bluuebunny/crossref_metadata_2025_split huggingface dataset:
CEREBRAL PALSY IN IBADAN, NIGERIA
Authors: Nottidge Vidal A. , Okogbo Michael E. 
Published: July 2010

SUMMARYIn a three‐year study of cerebral palsy (CP)., CP accounted for 16·2 per cent of new referrals to a child neurology clinic. 63 per cent of these had potentially preventable causes (not including intracranial infections), associated with chronic shortage of care personnel and inadequate finances for effective rehabilitation services. It is suggested that training and deployment of nurse‐physiotherapists, combined with intensive health education, is a feasible solution to the problem.RÉSUMÉI.M.C. à Ibadan, au NigériaAu cows d'une etude de trois ans sur I'Infirmité motrice cérébrale (I.M.C.), celle‐ci était responsable de 16,2 pour cent des premières consultations dans un service de neurologie infantile. Dans 63 pour cent de ces cas, la cause était potentiellemerit évitatile (sans inclure les infections intra‐craniennes), associeéà un déficit chronique de soins par personnel et un financement insuffisant pour une rééducation efficace. Les auteurs pensent que la formation et la diffusion d'infirmières rééducatrices, associées à une éducation sanitaire intensive, est une solution realiste au problème.ZUSAIMMENFASSUNGCerebral pa rese in Ibadan, NigeriaBei einer dreijährigen Studie über Cerebralparese (CP) fand sich, daß 16·2 Prozent der Neuaufnahmen in einer neuropädiatrischen Klinik eine Cerebralparese hatten. 63 Prozent davon hätten möglicherweise verhindert werden können (intracranielle Infektionen ausgenommen), sie mußten im Zusammenhang mit chronischem Personalmangel und unzureichender finanzieller Unterstützung effektiver Rahabilitationsangebote gesehen werden. Die Autoren sind der Ansicht, daß die Ausbildung und Einstellung von Krankenschwester‐Physiotherapeuten, in Verbindung mit intensiver Gesundheitserziehung, eine mögliihe Lösung des Problems ist.RESUMENParálisis cerebral en Ibadan, NigeriaEn un estudio de tres años sobre la Parálisis Cerebral (PC), ésta constituía el 16,2 por ciento de los casos muevos vistos en una clínica neurológica. El 63 por ciento de ellos eran por causas potencalmente prevenibles (sin incluir las infecciones intracraneales), en asociación con una insuficiencia crónica de personal adecuado y una sjtuación financiera insuficiente para cubrir las necesidades de los servicios de rehabilitación. Se sugiere que una posible solución asequible debe consistir en el entrenamiento y expansión de las enfermeras‐fisioterapeutas, en combinación con una intensiva educación sanitaria.
IMPROVEMENT OF FUNCTIONAL SITTING POSITION FOR CHILDREN WITH CEREBRAL PALSY
Authors: Myhr Ulla , von Wendt Lennart 
Published: July 2010

SUMMARYTwenty‐three children with cerebral palsy were photographed and video‐filmed in six different sitting positions—including a hypothetical functional position—and the video‐films and photographs were analysed. It was found that pathological movements were minimised and postural control and arm and hand function best when the child was sitting in a forward‐tipped seat, with a firm backrest supporting the pelvis, arms supported against a table and feet permitted to move backward.RÉSUMÉVers une position assise fonctionnelle pour les enfonts IMCVingt‐trois enfants IMC ont kte photographie et pris en vidéo dans six positions différentes—incluant une position fonctionnelle hypothétique—et vidéos et photographies ont été analysees. II a été observé que les mouvements anormaux étaient minimises, le controle postural et les fonctions des mains et des bras optimisés, lorsque l'enfant était assis dans un siège incliné vers I'avant, un point d'appui ferme pour supporter le bassin, les bras supportés par une table et les pieds libres de se déplacer vers I'avant.ZUSAMMENFASSUNGFunktionelIe Sitzposition bei Kindern mit Cerebralparese23 Kinder mit Cerebralparese wurden in sechs verschiedenen Positionen photographiert und rnit der Videokamera gefilmt—einschlieljlich einer hypothetischen funktionellen Position. Die Videofilme und Photographien wurden analysiert. Man fand heraus, daß die pathologischen Bewegungen abnahmen und die Haltungskontrolle und die Arm—und Handfunktion am besten waren, wenn das Kind in einem nach vorn geneigten Sitz saß, mit einer festen Rückenstütze zur Stützung des Beckens, die Arme gegen einen Tisch gestützt und mit rückwärtiger Bewegungsfreiheit der Füße.RESUMENHacia una sedestación funcional en niños con parálisis cerebralVeintitrés niños con parálisis cerebral fueron fotografiados y videofilmados en seis posiciones diferentes, incluyendo una hipotética posicion funcional, analizándose las imagenes obtenidas. Se halló que los movimientos patológicos se minimizaban y que el control postural y la funcion del brazo y la mano mejoraban cuando el niño estaba sentado en un asiento inclinado hacia adelante, con un firme soDorte dorsal Dara descansar la pelvis, los brazos apoyados sobre una mesa y con los pies pudiédose mover hacia atrás
Effect of Early Corticosteroid Therapy for Landau‐Kleffner Syndrome
Authors: Lerman Pinclias , Lerman‐Sagie Tally , Kivity Sara 
Published: July 2010

SUMMARYFour children treated for seizures between 1980 and 1986 were diagnosed as having Landau‐Kleffner syndrome (acquired aphasia with convulsive disorder), following the onset of aphasia. They received early and prolonged ACTH or corticosteroid therapy, with high initial doses. In all four cases the EEG promptly became normal, with subsequent long‐lasting remission of the aphasia and improvement of seizure control. Three to six years after discontinuation of hormone therapy the children are off medication and free from seizures and language disability.RÉSUMÉEffets du traitement précoce par corticostéroïdes dans le syndrome de Landay‐KleffnerUn diagnostic de syndrome de Landau‐Kleffner (aphasie acquise et convulsions) a été porté chez quatre enfants traités pour crises comitiales entre 1980 et 1986, à la suite du diagnostic d'aphasie. Ces enfants reçurent un traitment précoce et prolongé par ACTH ou corticostéroïdes, avec des doses initiales élévees. Dans les quatre cas, l'EEG fut rapidement normalisé, avec une rémission ultérieure de longue durée de l'aphasie et amélioration du controle des crises. Trois à six ans après la cessation du traitement hormonal, les enfants sont sans traitement, sans crises ni troubles de langage.ZUSAMMENFASSUNGDie Wirkumg frühzeitiger Corticoidtherapie beim Landau‐Kleffner SyndromBei vier Kindern, die in den Jahren 1980 bis 1986 wegen Krampfanfällen behandelt wurden, wurde mit dem Auftreten einer Aphasie die Diagnose Landau‐Kleffner Syndrome (erworbene Aphasie mit Krampfleiden) gestellt. Sie bekamen frühzeitig und über längere Zeit ACTH oder Corticoide in hoher Anfangsdosis. In allen vier Fällen normalisierte sich das EEG sofort, und es folgte eine anhaltende Remission der Aphasie und eine bessere Anfallskontrolle. Drei bis sechs Jahre nach dem Absetzen der Hormontherapie sind die Kinder ohne Medikamente, anfallsfrei und ohne Sprachbehinderung.RESUMENEl efecto de la terapia precoz con corticosteroides en el sindrome de Landau‐KleffnerCuatro niños tratados por convulsiones entre 1980 y 1986 fueron diagnosticados de sindrome de Landau‐Kleffner (afasia adquirida con alteración convulsiva) a consecuencia del inicio de una afasia. Recíbieron una terapia precoz y prolongada con ACTH o con corticoides con dosis iniciales altas. En los cuatro casos el EEG se normalizó rápidamente con una remisión posterior de larga duración de la afasia y mejoría en el control de las convulsiones. Tres y seis años después de interrumpir la hormonoterapia los niños no toman ninguna medicación y estan libres de convulsiones y alteraciones en el lenguaje.
PURINE METABOLITES AND PYRIMIDINE BASES IN CEREBROSPINAL FLUID OF CHILDREN WITH SIMPLE FEBRILE SEIZURES
Authors: Rodríguez‐Núñez Antonio , Camiña Félix , Lojo Santiago , Rodríguez‐Segade Santiago , Castro‐Gago Manuel 
Published: July 2010

SUMMARYAdenosine monophosphate, inosine monophosphate, inosine, adenosine, guanosine, adenine, guanine, hypoxanthine, xanthine, uric acid and pyrimidine bases were determined in the CSF of 18 children after simple febrile seizures and in a control group. There was no statistically significant difference between the two groups for any of these metabolites. This suggests that simple febrile seizures neither significantly disturb the metabolism of nucleotides, nucleosides or bases, nor significantly deplete neuron adenosine triphosphate ATP levels.RÉSUMÉ Métabolites puriques et bases pyrimidiques dans le LCR d'enfant avec crises hyperthermiques L'adénosine monophosphate, l'inosine monophosphate, l'inosine, l'adénosine, la guanosine, l'adénine, la guanine, l'hypoxanthine, la xanthine, l'acide urique et les bases pyrimidiques ont été mesurés dans le LCR de 18 enfants après crises comitiales hyperthermiques simples et dans un groupe contrôle. II n'y avait de différences significatives entre les deux groupes pour aucun des métabolites. Cela suggère que les crises hyperthermiques simples ne perturbent pas le métabolisme des nucléotides des nucléosides ou des bases et n'abaissent pas significativement les taux d'adénosine triphoshate (ATP) neuronique.ZUSAMMENFASSUNG Purinmetabolite und Pyrimidinbasen im Liquor von Kindern mit einfachen Fieberkrämpfen Adenosinmonophosphat, Inosinmonophosphat, Inosin, Adenosin, Guanosin, Adenin, Guanin, Hypoxanthin, Xanthin, Harnsäure und Pyrimidinbasen wurden im Liquor von 18 Kindern mit einfachen Fieberkrämpfen und bei Kontrollkindern bestimmt. Für keinen dieser Metaboliten fand sich zwischen den beiden Gruppen ein signifikanter Unterschied. Das bedeutet, daß einfache Fieberkrämpfe weder den Metabolismus von Nukleotiden, Nukleosiden oder Basen signifikant stören, noch die neuronalen Adenosintriphosphatspiegel (ATP) signifikant verändern.RESUMEN Metabolitos púricos y bases pirimidínicas en el LCR de niños con convulsiones febriles simples Se determinaron adenosina monofosfato, inosina monofosfato, inosina, adenosina, guanosina, guanina, hipoxantina, xantina, acido, úrico y bases pirimidinicas en el LCR de niños tras convulsiones febriles simples, así como en un grupo control. No había diferencia estadísticamente significativa entre ambos grupos para ninguno de los metabolitos citados. Esto sugiere que las convulsiones febriles simples no alteran el metabolismo de los nucleótidos, nucleósidos o bases, ni ocasiona ninguna depleción significativa en los niveles neuronales de adenosin trifosfato ATP.
Krabbe Disease in Monozygotic Triplets
Authors: Arroyo Hugo A. , Grippo Jorge , Taratuto Analia , Duffau Jorge , Chamoles Nestor 
Published: July 2010

SUMMARYThe authors report an extremely rare case of monozygotic triplets with globoid cell leukodystrophy (Krabbe disease). Born to healthy, non‐related, heterozygous parents, all three girls presented with typical signs of β‐galactocerebrosidase deficiency before one year of age and died within the first 41 months of life. The literature is briefly reviewed.RÉSUMÉMaladie de Krabbe chez des triplets monozygotesLes auteurs rapportent le cas extrèmement rare de triplets monozygotes atteints de leucodystrophie à cellules globoïdes (Maladie de Krabbe). Nées de parents en bonne santé, hétérozygotes non consanguins, les trois filles ont présenté les signes typiques d'une déficience en β‐galactocérébrosidase avant l'âge d'un an et moururent durant les 41 premiers mois de vie. Une brève revue de la littérature est faite.ZUSAMMENFASSUNGKrabbe Syndrom bei monozygoten DrillingenDie Autoren berichten über einer äußerst seltenen Fall von monozygoten Drillingen mit einer Globoidzell‐Leukodystrophie (Krabbe Syndrom). Als Kinder gesunder, nicht verwandter, hetrozygoter, Eltern zeigten alle drei Mädchen bereits im erstan Lebensjahr die typischer Symptome eines β‐Galaktocerebrosidasemangels und starben innerhalb der ersten 41 Lebensmonate. Es wird ein kurzer Literaturüberblick gegeben.RESUMENEnfermedad de Krabbe en trillizas monozigotasLos autores presentan una caso extremadamente raro de triplete monozigotas con leucodistrofia de células globoides (enfermedad de Krabbe). Nacidas de padres sanos, no consanguineos, heterozigotas, las tres niños presentaban signos típicos de deficiencia de β‐galactocerebrosidasa antes del año de edad y fallecieron dentro de los 41 meses de vida. Se revisa brevemente la literatura.
The Surgical Management of Drooling
Authors: BURTON MARTIN J. 
Published: July 2010

SummaryAs with all branches of surgery, selection of the appropriate operative procedure for a particular patient involves careful weighing of all the alternatives and full discussion with the patient and carers. Each of the procedures described has its devotees and detractors. For an individual patient, however, the risks of each, the likely postoperative course and the results of the surgery‐both in terms of the expected chance of improvement in drooling and the presence or otherwise of residual scarring or taste‐must be balanced to determine the optimum plan for treatment.The long‐term results of submandibular duct transposition for drooling in the author's own institution have recently been reported41. An initial improvement in the drooling of all patients was maintained for at least two years in 17 of 20 patients. Only two patients experienced complications requiring further surgery (ranulas in each case). It is suggested that these very satisfactory results, achieved without external scarring and without compromising the sense of taste, support the contention that submandibular duct transposition is the surgical treatment of choice for children and young people with cerebral palsy who drool excessively.
Positional Asphyxia in Individuals with Severe Cerebral Palsy
Authors: Brogan Thomas , Fligner Corrinne L. , McLaughlin John F. , Feldman Kenneth W. , Kiesel Eric L. 
Published: July 2010

SUMMARYThe authors report the accidental death by positional asphyxia of three individuals with cerebral palsy occurring after they had been placed in bed for the night. During the five‐year period between 1984 and 1989, 12 per cent of deaths from positional asphyxia in King County, Washington, involved individuals with cerebral palsy. Such accidents are similar to those occurring among healthy young children, perhaps because both groups have limited motor skills. Further research into accidents among disabled persons may clarify their special risks and possibly lead to modifications in bed design.RÉSUMÉAsphyxie de position chez certains grands I.M.O.C.Les auteurs ràpportent la mort accidentelle par asphyxie de position de trois I.M.O.C. après qu'ils aient été mis au lit pour la nuit. Durant la période de cinq ans, entre 1984 et 1989, 12 pour cent des décès par asphyxie de position dans le comté de King, Washington, concernaient des I.M.O.C. De tels accidents sont comparables à ceux qui surviennent chez de très jeunes enfants en bonne santé, peut‐être du fait d'un caractère commun de capacités motrices Iimitées. Des recherches ultérieures sur les accidents chez les personnes atteintes d'incapacité devraient préciser les risques propres et peutêtre conduire à une modification de l'architecture des lits.ZUSAMMENFASSUNGPositionsasphyxie bei Patienten mit schwerer CerebralpareseDie Autoren berichten über den plötzlichen Tod durch Positionsasphyxie bei drei Patienten mit Cerebralparese, nachdem sie zur Nacht ins Bett gelegt worden waren. In den fünf Jahren von 1981 bis 1989 waren im King County, Washington, 12 Prozent der Todesfälle durch Positionsasphyxie Patienten mit Cerebralparese. Solche Unglücksfälle ähneln denen, die bei gesunden Kleinkindern auftreten, vielleicht weil beide Gruppen begrenzte motorische Fähigkeiten besitzen. Weitere Untersuchungen von Unglücksfällen bei behinderten Patienten können eventuell ihre besonderen Risiken aufklären und möglicherweise dazu führen, adß die Bettform modifiziert wird.RESUMENAsfixia posicional en individuos con parálisis cerebral graveLos autores refieren la muerte accidental por asfixia posicional de tres casos con parálisis cerebral, después de haber sido colocados en la cama para pasar la noche. En el periodo de cinco años entre 1984 y 1989 el 12 por ciento de asfixias posicionales en el condado de King, Washington, tuvo lugar en individuos con parálisis cerebral. Estos accidentes son semejantes a los ocurridos en niños pequeños sanos, tal vez porque ambos grupos tienen una limitación de la capacidad motora. Una investigación de los accidentes acaecidos en personas minusválidas puede esclarecer sus riesgos especiales y posiblemente lleve a modificar el diseño de las camas.
Architecture of the medial gastrocnemius in children with spastic diplegia
Authors: Shortland Adam P , Harris Charlotte A , Gough Martin , Robinson Richard O 
Published: July 2010

Due to an error in the December 2001 version of this article the corrected version is published below.Ultrasound images were obtained of the medial gastrocnemius at different ankle joint positions with the knee extended. Fascicle length and deep fascicle angle were measured in five normally developing adults (mean age 33 years, age range 24 to 36 years) and in five normally developing children (mean age 7.8 years, age range 7 to 11 years), and in seven children with spastic diplegia (mean age 10 years, age range 6 to 13 years). These architectural variables were similar in the groups of normally developing adults and children. Importantly, no statistical difference could be found between the normally developing children and those with diplegia for fascicle length. Deep fascicle angles were reduced significantly in the clinical group at a particular ankle joint angle but not at the resting angles. The difference in deep fascicle angles is explained as a function of resting muscle length and is not attributed any clinical importance. Our results do not explain the structural origin of muscle contracture explicitly. However, they do indicate that most of the fixed shortness in the medial gastrocnemii of ambulant children with spastic diplegia is not due to reduced muscle fibre length. We suggest that muscle contracture may be better explained in terms of shortness of the aponeuroses of pennate muscles, such as the medial gastrocnemius, through reduced muscle fibre diameter.
Early Ordovician U‐Pb metamorphic ages of the eclogite‐bearing Seve Nappes, Northern Scandinavian Caledonides
Authors: ESSEX R. M. , GROMET L. P. , ANDRÉASSON P.‐G. , ALBRECHT L. 
Published: July 2010

ABSTRACT Eclogite‐grade metamorphism of the Seve Nappe Complex (SNC) in Norrbotten, Sweden, records the attempted subduction of the Baltic continental margin during the early Palaeozoic evolution of the Iapetus Ocean. Metamorphic titanite sampled from several calcsilicate gneisses of the SNC in Norrbotten occurs as part of a prograde, eclogite facies metamorphic mineral assemblage and yields concordant to nearly concordant U/Pb ages of 500–475 Ma. Later structural disruption of these rocks occurred during the Siluro‐Devonian Scandian phase of the Caledonide orogeny, but the U/Pb systematics show no evidence of a second generation (metamorphic or recrystallized) of titanite, or of post‐Early Ordovician disturbance through Pb loss. Hence the U/Pb ages are believed to record the time of prograde mineral growth during eclogite facies metamorphism of the SNC.These results support earlier Sm/Nd and 40Ar/39Ar studies indicating an Early Ordovician metamorphic age for the eclogitic Norrbotten SNC, and confirm the Early Ordovician destruction of at least this segment of the Palaeozoic passive margin of Baltica. These results indicate that the SNC in the northern Scandinavian Caledonides was subducted and metamorphosed to high grade some 50–70 Myr prior to the high‐grade metamorphism of the SNC in the central Scandinavian Caledonides. This result requires significantly different early Palaeozoic tectonic histories for rocks mapped as SNC in the northern Caledonides and those in the central Caledonides, despite a seemingly similar tectonostratigraphic position and broadly similar high‐grade metamorphism.
Metamorphic petrology and zircon geochronology of high‐grade rocks from the central Mozambique Belt of Tanzania: crustal recycling of Archean and Palaeoproterozoic material during the Pan‐African orogeny
Authors: Sommer H. , Kröner A. , Hauzenberger C. , Muhongo S. , Wingate M. T. D. 
Published: July 2010

AbstractNew data on the metamorphic petrology and zircon geochronology of high‐grade rocks in the central Mozambique Belt (MB) of Tanzania show that this part of the orogen consists of Archean and Palaeoproterozoic material that was structurally reworked during the Pan‐African event. The metamorphic rocks are characterized by a clockwiseP–Tpath, followed by strong decompression, and the time of peak granulite facies metamorphism is similar to other granulite terranes in Tanzania. The predominant rock types are mafic to intermediate granulites, migmatites, granitoid orthogneisses and kyanite/sillimanite‐bearing metapelites. The meta‐granitoid rocks are of calc‐alkaline composition, range in age from late Archean to Neoproterozoic, and their protoliths were probably derived from magmatic arcs during collisional processes. Mafic to intermediate granulites consist of the mineral assemblage garnet–clinopyroxene–plagioclase–quartz–biotite–amphibole ± K‐feldspar ± orthopyroxene ± oxides. Metapelites are composed of garnet‐biotite‐plagioclase ± K‐feldspar ± kyanite/sillimanite ± oxides. Estimated values for peak granulite facies metamorphism are 12–13 kbar and 750–800 °C. Pressures of 5–8 kbar and temperatures of 550–700 °C characterize subsequent retrogression to amphibolite facies conditions. Evidence for a clockwiseP–Tpath is provided by late growth of sillimanite after kyanite in metapelites. Zircon ages indicate that most of the central part of the MB in Tanzania consists of reworked ancient crust as shown by Archean (c. 2970–2500 Ma) and Palaeoproterozoic (c. 2124–1837 Ma) protolith ages. Metamorphic zircon from metapelites and granitoid orthogneisses yielded ages ofc. 640 Ma which are considered to date peak regional granulite facies metamorphism during the Pan‐African orogenic event. However, the available zircon ages for the entire MB in East Africa and Madagascar also document that peak metamorphic conditions were reached at different times in different places. Large parts of the MB in central Tanzania consist of Archean and Palaeoproterozoic material that was reworked during the Pan‐African event and that may have been part of the Tanzania Craton and Usagaran domain farther to the west.