bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and trends in physical therapy interventions for erectile dysfunction: A Scopus‐based bibliometric analysis (1989–2022)
Authors: Alzharani Abdulaziz Ali Y. , Alshami Ali M. , Khan Muhammad Ajmal , Siddique Nadeem , Abualait Turki 
Published: May 2024

AbstractBackgroundErectile dysfunction (ED) is a condition that affects many males. Physical therapy (PT) is the one potential treatment for ED that may improve blood flow, muscle strength, and other factors that may contribute to the issue. Data on the prevalence and trends of research on PT for ED are lacking.ObjectiveThis study aimed to evaluate the literature trends in PT for ED via bibliometric and visualized analysis.MethodsData on publications were collected from Scopus covering the period between 1989 and 2022. To refine the data, bibliometric analyses were conducted using Microsoft Access, Microsoft Excel, an online visualization platform, and BiblioAnalytics. Power BI and Bibliomaster were used to generate figures and tables, while Biblioshiny and VOSviewer were used for visualization.ResultsA total of 494 documents were identified. The year 2019 generated the largest number of publications, with a total of 54. These studies have received 12,917 citations related to PT for ED. The most common document type was the original article with 283 publications. The University of California, USA, was the most productive institution on this topic, with 21 publications and 2,035 citations. The USA led all countries with 114 publications on the topic. The Journal of Sexual Medicine secured the top ranking with an h‐index of 18. The main topics studied were erectile dysfunction, shockwave therapy, and physiotherapy.ConclusionThe number of publications on PT for ED has demonstrated an upward trend over the last three decades.
Family integrated care: State of art and future perspectives
Authors: Moreno‐Sanz Bárbara , Alferink Milène Tirza , O'Brien Karel , Franck Linda S. 
Published: May 2024

AbstractFamily integrated care (FICare) represents a contemporary approach to health care that involves the active participation of families within the healthcare team. It empowers families to acquire knowledge about the specialised care required for their newborns admitted to neonatal intensive care unit (NICU) and positions them as primary caregivers. Healthcare professionals in this model act as mentors and facilitators during the hospitalisation period. This innovative model has exhibited notable enhancements in both short‐ and long‐term health outcomes for neonates, alongside improved psychological well‐being for families and heightened satisfaction among healthcare professionals. Initially designed for stable premature infants and their families, FICare has evolved to include critically ill premature and full‐term infants. Findings from recent studies affirm the safety and feasibility of FICare as a NICU‐wide model of care, benefiting all infants and families. The envisioned expansion of FICare focusses on sustainability and extending its implementation, recognising the necessity for tailored adaptations to suit varying diverse cultural and socio‐economic contexts.
Weekly information communication technology availability demand and family experiences in dual‐earner couples: A perspective from the spillover–crossover model
Authors: Zhang Zhenduo , Xiao Huan , Zheng Junwei , Shen Yifei , Sun Xiuxia 
Published: May 2024

AbstractThe prevalence of information communication technology (ICT) enables employees to conveniently communicate with coworkers and clients regardless of time and place. However, recent studies have revealed a negative side of ICT use, especially its capacity to invade the family domain. This study was developed based on the spillover–crossover model (SCM) to test how ICT availability demand shapes employees' family experiences and how this demand crosses over to spouses. A total of 961 cases nested in 101 dual‐earner couples were collected using a 10‐week experience sampling method. Multilevel structural equation modelling revealed that (1) employees' work interference with family (WIF) mediated the indirect impact of employees' ICT availability demand on their family satisfaction and family undermining; (2) employees' WIF mediated the indirect impact of employees' ICT availability demand on their spouses' family satisfaction and family undermining; and (3) employees' ICT control buffered these two indirect relationships by which employees' ICT availability demand impacted their own and their spouses' family satisfaction and family undermining. This research elaborates on the spillover and crossover process through which ICT availability demand shapes family experience, thus contributing to the literature on ICT availability demand and the SCM.
The Burden of the Ego‐Ideal and the Refusal of Development
Authors: Rigg Peter 
Published: May 2024

AbstractThis study provides an account of the way shame, intrusion or other adverse experiences in early childhood can prevent genuine identification with an ego‐ideal, which is felt to be a burden. I argue that the ego‐ideal is necessary to impel the individual towards continual growth and that its absence vitiates the formation of a durable ego. The paper points out the consequences for the subject, which include incapacitation of the ego and the desire to circumvent life.
Motor coordination induces social identity—A novel paradigm for the investigation of the group performance‐identity link
Authors: Krishna Anand , Götz Felix J. 
Published: May 2024

AbstractJoint action theorizing implies that any coordinated behaviour that induces co‐representation with a partner should increase social identification, especially when the associated actions require a high degree of coordination and are experienced as being performed effectively. The current research provides a first test of this new theoretical prediction for complementary (rather than synchronous) joint actions. In each of two pre‐registered experiments establishing a novel paradigm, participants performed a digital joystick task with a joint performance goal with three different partners. The task varied in coordination requirements across partners. In Experiment 1, results showed that when task segments were discrete between partners, they identified less as a group than when they had to coordinate their behaviour. Surprisingly, although constant coordination increased co‐representation relative to intermittent coordination, it did not correspondingly increase social identification. However, performance correlated positively with identification; as performance was worse when participants had to coordinate, this may explain the results. Experiment 2 showed that performance is causally linked to identification when coordination is necessary. Taken together, our results suggest that experiencing effective coordination leads to greater social identification. In general, paradigms capable of examining the perceptual and motor aspects of collective behaviour may offer a new perspective on social identification in general and the performance‐identification link in particular.
A comprehensive overview of metaplastic breast cancer: Features and treatments
Authors: Yan Qiaoke , Deng Yuwei , Zhang Qingyuan 
Published: May 2024

AbstractMetaplastic breast cancer is a rare, aggressive, and chemotherapy‐resistant subtype of breast cancers, accounting for less than 1% of invasive breast cancers, characterized by adenocarcinoma with spindle cells, squamous epithelium, and/or mesenchymal tissue differentiation. The majority of metaplastic breast cancers exhibit the characteristics of triple‐negative breast cancer and have unfavorable prognoses with a lower survival rate. This subtype often displays gene alterations in the PI3K/AKT pathway, Wnt/β‐catenin pathway, and cell cycle dysregulation and demonstrates epithelial–mesenchymal transition, immune response changes, TP53 mutation, EGFR amplification, and so on. Currently, the optimal treatment of metaplastic breast cancer remains uncertain. This article provides a comprehensive review on the clinical features, molecular characteristics, invasion and metastasis patterns, and prognosis of metaplastic breast cancer, as well as recent advancements in treatment strategies.
Identifying Deficiencies in Children's Residential Care in Finland: Inspectors' Views on Working With Information
Authors: Repo Jenni 
Published: May 2024

ABSTRACTAbusive and illegal practices in residential care are a recognised issue in child welfare internationally; thus, the question of how these institutions are supervised is important. However, children's residential care is complex by nature, making its supervision a challenging task. This article examines residential care supervision by looking at the ‘knowledge work’ that two central legality supervisors in Finland—the Parliamentary Ombudsman and Regional State Administrative Agencies—conduct when inspecting children's residential homes. Here, ‘knowledge work’ refers to the process of working with information to identify deficiencies in care. Eleven interviews and 16 inspection reports are analysed with a focus on the nature of the information that these supervisors gather when inspecting residential units and how they evaluate the significance and reliability of the information. The results show that to complete their institutional task, the inspectors gather information from various sources, including documents and interviews with children. The significance of the information is then assessed by comparing it with legislation and the supervisory mandate, and its reliability is verified by considering the diverse information sources as a whole collection of information. The results suggest that how well ‘knowledge work’ is conducted highly affects the impact of supervision.
The biological behavior and clinical outcome of pituitary adenoma are affected by the microenvironment
Authors: Li Yuhe , Ren Xiufang , Gao Wei , Cai Ruikai , Wu Jianqi , Liu Tianqi , Chen Xin , Jiang Daoming , Chen Chong , Cheng Quan , Wu Anhua , Cheng Wen 
Published: May 2024

AbstractBackgroundPituitary adenoma is one of the most common brain tumors. Most pituitary adenomas are benign and can be cured by surgery and/or medication. However, some pituitary adenomas show aggressive growth with a fast growth rate and are resistant to conventional treatments such as surgery, drug therapy, and radiation therapy. These tumors, referred to as refractory pituitary adenomas, often relapse or regrow in the early postoperative period. The tumor microenvironment (TME) has recently been identified as an important factor affecting the biological manifestations of tumors and acts as the main battlefield between the tumor and the host immune system.Main bodyIn this review, we focus on describing TME in pituitary adenomas and refractory pituitary adenomas. Research on the immune microenvironment of pituitary adenomas is currently focused on immune cells such as macrophages and lymphocytes, and extensive research and experimental verifications are still required regarding other components of the TME. In particular, studies are needed to determine the role of the TME in the specific biological behaviors of refractory pituitary adenomas, such as high invasion, fast recurrence rate, and high tolerance to traditional treatments and to identify the mechanisms involved.ConclusionOverall, we summarize the similarities and differences between the TME of pituitary adenomas and refractory pituitary adenomas as well as the changes in the biological behavior of pituitary adenomas that may be caused by the microenvironment. These changes greatly affect the outcome of patients.
CD22 blockade aggravates EAE and its role in microglia polarization
Authors: Xiang Weiwei , Wang Kan , Han Lu , Wang Ze , Zhou Zhiyang , Bai Shuwei , Peng Jing , Xie Chong , Guan Yangtai 
Published: May 2024

AbstractAimsMultiple sclerosis (MS) is a neuroinflammatory demyelinating disease. Microglia are reportedly involved in the pathogenesis of MS. However, the key molecules that control the inflammatory activity of microglia in MS have not been identified.MethodsExperimental autoimmune encephalomyelitis (EAE) mice were randomized into CD22 blockade and control groups. The expression levels of microglial CD22 were measured by flow cytometry, qRT–PCR, and immunofluorescence. The effects of CD22 blockade were examined via in vitro and in vivo studies.ResultsWe detected increased expression of microglial CD22 in EAE mice. In addition, an in vitro study revealed that lipopolysaccharide upregulated the expression of CD22 in microglia and that CD22 blockade modulated microglial polarization. Moreover, an in vivo study demonstrated that CD22 blockade aggravated EAE in mice and promoted microglial M1 polarization.ConclusionCollectively, our study indicates that CD22 may be protective against EAE and may play a critical role in the maintenance of immune homeostasis in EAE mice.
Safety and efficacy of three‐dimensional versus two‐dimensional endoscopy in otolaryngology surgery and training: A systematic review
Authors: Ban Yuxin , Mcneely Brendan , Chadha Neil K. , Felton Mark 
Published: May 2024

AbstractObjectiveThree‐dimensional (3D) endoscopy has been developed to provide depth perception to allow for improved visualisation during otolaryngology surgery. We conducted a systematic review to determine the surgical safety and efficacy of 3D endoscopy in comparison to two‐dimensional (2D) endoscopy in performing otolaryngology procedures, and the role of 3D endoscopy as a training tool for novice otolaryngology surgeons.MethodsPrimary studies were identified through MEDLINE, Embase and Web of Science databases, which were searched for articles published through June 2022 that compared the outcomes of 2D and 3D endoscopy in otolaryngology surgical procedures or otolaryngology‐relevant simulations. Candidate articles were independently reviewed by two authors.ResultsA total of 18 full‐text articles met inclusion criteria for this study. In clinical trials (n = 8 studies, 362 subjects), there were no significant differences in performance time, intraoperative or postoperative complications with 3D endoscopes when compared to 2D. In simulation studies (n = 10 studies, 336 participants), 3D endoscopes demonstrated a decreased error rate (n = 5 studies) and shorter performance time (n = 3 studies). Studies also reported improved depth perception (n = 14 studies) and visualisation preference (n = 5 studies) with 3D over 2D systems. The 3D systems were found to have a shorter learning curve and better manoeuvrability among novice surgeons.Conclusion3D endoscopy showed equivalent safety and efficacy compared to 2D endoscopy in otolaryngology surgery. The improved depth perception and performance for novices using 3D endoscopes suggests the technology may be superior to 2D endoscopes as a training tool for otolaryngology surgeons.
Cost‐utility analysis and drug pricing for tirzepatide for type 2 diabetes in the Chinese market compared with semaglutide
Authors: Hu Shanshan , Shi Chenyang , Ma Yuhang , Wang Shuowen , Gu Shengying , Qi Chendong , Fan Guorong 
Published: May 2024

AbstractAimTo investigate the most matchable price of tirzepatide (TIRZ) compared with semaglutide (SEMA) in the treatment of type 2 diabetes in China.MethodsThe patient cohort and clinical efficacy data were derived from the SURPASS‐2 trial. Cost‐utility analysis and a binary search were performed to identify the most matchable price of TIRZ from a Chinese healthcare provider's perspective.ResultsAfter lifetime simulation, the quality‐adjusted life years of TIRZ 5, 10, 15 mg and SEMA 1 mg were 11.17, 11.21, 11.27 and 11.12 years, respectively. Despite an initial assumption that the annual cost of TIRZ equals that of SEMA, our analysis revealed that TIRZ is probably more cost‐effective than SEMA. A thorough evaluation of pricing showed that the cost ranges for TIRZ at doses of 5, 10 and 15 mg were $1628.61‐$1846.23, $1738.40‐$2140.95 and $1800.30‐$2430.81, respectively. After adjustment in the univariate sensitivity analysis, the cost ranges for TIRZ 5, 10 and 15 mg were $1542.68‐$1757.57, $1573.00‐$1967.16 and $1576.54‐$2133.96, respectively. These cost intervals were validated through robust probabilistic sensitivity analysis and scenario analysis, except for the cost range for TIRZ 5 mg.ConclusionsThis study shows that, using SEMA as a reference, the annual costs for TIRZ 10 and 15 mg are $1573.00‐$1967.16 and $1576.54‐$2133.96, respectively, for patients with type 2 diabetes in China.
Cardiometabolic factors and population risks of cardiovascular disease in community‐dwelling adults with varied blood pressure statuses
Authors: Qiu Weida , Cai Anping , Nie Zhiqiang , Wang Jiabin , Ou Yanqiu , Feng Yingqing 
Published: May 2024

AbstractAimsTo examine the differential associations between cardiometabolic risk factors and cardiovascular disease (CVD), and to evaluate the population‐attributable fractions (PAFs) for CVD among community‐dwelling adults with varied blood pressure (BP) statuses.MethodsThis prospective cohort study included participants without prevalent CVD from a subcohort of the China Patient‐Centred Evaluative Assessment of Cardiac Events Million Persons Project. Participants were divided into four BP groups according to the American College of Cardiology/American Heart Association guidelines. The study exposure comprised the selected cardiometabolic risk factors, including waist circumference (WC), body mass index, (BMI) heart rate, fasting blood glucose (FBG), low‐density lipoprotein cholesterol, and remnant cholesterol. The outcome was hospitalizations for CVD. Cox proportional hazard models were conducted, and the PAFs were calculated in the analysis.ResultsAmong the 94 183 participants (39.0% were men, mean age: 54.2 years), 26.6% had Stage 1 hypertension and 30.8% had Stage 2 hypertension. A total of 6065 hospitalizations for CVD were captured after a median follow‐up of 3.5 years. BP (per 1‐standard deviation [SD]: hazard ratio [HR] 1.34, 95% confidence interval [CI] 1.29, 1.40), FBG (per 1‐SD: HR 1.16, 95% CI 1.14, 1.19) and WC (per 1‐SD: HR 1.41, 95% CI 1.36, 1.47) were three major contributors to CVD events. BP status significantly modified the associations of abdominal obesity, suboptimal BMI, suboptimal heart rate and abnormal FBG with CVD, with stronger associations with CVD observed in optimal BP groups compared to hypertensive groups (p for risk factor‐by‐BP group interaction <0.05). Participants with all cardiometabolic risk factors were at the highest risk for CVD, accounting for 35.6% (95% CI 30.0, 40.8) of the PAF for CVD. Among the risk factors, BP control explained the highest PAF for CVD (15.1%, 95% CI 8.2, 21.4) The overall PAFs of cardiometabolic risk factors for CVD were higher among the normotensive participants compared to the hypertensive participants.ConclusionsThe awareness and control rates of hypertension were extremely low among Southern Chinese adults. BP status significantly modified the associations between cardiometabolic risk factors and CVD, and the overall PAFs for CVD were higher among people with normal BP. Dedicated efforts are needed to improve the management of cardiometabolic factors.
Cognitive brain activity before and after surgery in meningioma patients
Authors: Schouwenaars Irena T. , de Dreu Miek J. , Rutten Geert‐Jan M. , Ramsey Nick F. , Jansma J. Martijn 
Published: May 2024

AbstractNeuropsychological studies have demonstrated that meningioma patients frequently exhibit cognitive deficits before surgery and show only limited improvement after surgery. Combining neuropsychological with functional imaging measurements can shed more light on the impact of surgery on cognitive brain function. We aimed to evaluate whether surgery affects cognitive brain activity in such a manner that it may mask possible changes in cognitive functioning measured by neuropsychological tests. Twenty‐three meningioma patients participated in a fMRI measurement using a verbal working memory task as well as three neuropsychological tests focused on working memory, just before and 3 months after surgery. A region of interest based fMRI analysis was used to examine cognitive brain activity at these timepoints within the central executive network and default mode network. Neuropsychological assessment showed impaired cognitive functioning before as well as 3 months after surgery. Neuropsychological test scores, in‐scanner task performance as well as brain activity within the central executive and default mode network were not significantly different between both timepoints. Our results indicate that surgery does not significantly affect cognitive brain activity in meningioma patients the first few months after surgery. Therefore, the lack of cognitive improvement after surgery is not likely the result of compensatory processes in the brain. Cognitive deficits that are already present before surgery appear to be persistent after surgery and a considerable recovery period. Our study shows potential leads that comprehensive cognitive evaluation can be of added value so that cognitive functioning may become a more prominent factor in clinical decision making.
Diversity inhibits foliar fungal diseases in grasslands: Potential mechanisms and temperature dependence
Authors: Zhang Peng , Jiang Hongying , Liu Xiang 
Published: May 2024

AbstractA long‐standing debate exists among ecologists as to how diversity regulates infectious diseases (i.e., the nature of diversity‐disease relationships); a dilution effect refers to when increasing host diversity inhibits infectious diseases (i.e., negative diversity‐disease relationships). However, the generality, strength, and potential mechanisms underlying negative diversity‐disease relationships in natural ecosystems remain unclear. To this end, we conducted a large‐scale survey of 63 grassland sites across China to explore diversity‐disease relationships. We found widespread negative diversity‐disease relationships that were temperature‐dependent; non‐random diversity loss played a fundamental role in driving these patterns. Our study provides field evidence for the generality and temperature dependence of negative diversity‐disease relationships in grasslands, becoming stronger in colder regions, while also highlighting the role of non‐random diversity loss as a mechanism. These findings have important implications for community ecology, disease ecology, and epidemic control.
Multinational enterprises' lobbying and foreign subsidiary performance: Evidence from the U.S. in the context of the global financial crisis
Authors: Shirodkar Vikrant , Konara Palitha 
Published: May 2024

AbstractWhether corporate political activity (CPA) benefits firm performance is contested in the literature. However, the CPA‐performance relationship has been less explored in the international business context or in the context of macroeconomic shocks—notably the global financial crisis—during which multinational enterprises (MNEs) may be forced to revisit their market and non‐market strategies. In this study, we draw upon insights from the institutional theory and legitimacy perspectives to argue that the performance consequences of MNEs' lobbying in a host market are contingent upon the MNE's experience of operating in the host market, their lobbying frequency, and the subsidiary's technological intensity. The empirical analysis used to test our hypotheses is based on a panel dataset of 224 subsidiaries of foreign MNEs operating in the United States, spanning the 8‐year period 2005–2013, covering the years of the financial crisis. We find support for most of our hypotheses and contribute to the performance implications of CPA in international business contexts.