bluuebunny/crossref_metadata_2025_split huggingface dataset:
To What Extent Does Green Finance Influence Carbon Intensity: The Role of Green Innovation and Industrial Structure
Authors: Chen Jingpeng , Lin Haiying , Wang Yidi , Cai Zigong 
Published: May 2024

Abstract

Against the backdrop of global climate change and slowing economic growth, nations are urgently seeking strategies to both stimulate economic recovery and reduce carbon intensity (CI). In this context, China has prioritized the expansion of green finance as a pivotal mechanism for fostering green transformation and securing sustainable growth. This study delves into the effect of green finance on China's CI. Employing an empirical analysis across 30 Chinese provinces from 2007 to 2020, this paper leverages the entropy method to forge a comprehensive green finance indicator. The findings show green finance diminishing CI, predominantly driven by green innovation and industrial structure. Further examination using the threshold effect model reveals a pronounced threshold impact of green innovation and industrial structure on the efficacy of green finance in reducing CI, with the inhibitory effect of green finance peaking within an optimal threshold range. The heterogeneity test reveals that, compared to the western and northeastern regions, green finance has a more pronounced inhibitory effect on CI in the eastern and central regions. The research findings of this paper provide a perspective on how green finance facilitates the reduction of regional CI.
Parent-Mediated Eye Gaze Intervention in Young Autistic Children: ADOS-BOSCC Outcome Study
Authors: Husu Elina , Helminen Terhi M. , Muuvila Mari , Lauttia Jenni , Eriksson Kai , Nevalainen Jaakko , Kylliäinen Anneli 
Published: May 2024

Abstract

This study investigated the generalisation of a brief parent-mediated eye gaze intervention outcome across communication partners and different aspects of social behaviour in preschool-aged autistic children. ADOS-BOSCC change scores were compared between intervention and control groups in the short-term and long-term, showing no significant differences in domain-level changes. Item-level findings indicate that intervention showed generalisation of eye gaze across communication partners in the semi-structured researcher-child interaction after the intervention. Interestingly, the intervention seemed to partly alter the course of generalisation development in gestures and integration of vocal and non-vocal communication. Intervention temporarily slowed the progress in these areas, as evidenced in the control group’s greater improvement in the short-term. However, in the long-term, the intervention group achieved the same level as the control group in the gestures and integration. Overall, results indicate that parent-mediated interventions can facilitate the generalisation of children’s learning in targeted social skills across different contexts.
Novel insights into causal effects of lipid and lipid-lowering targets with autoimmune thyroid disease: A Mendelian randomization study
Authors: Su Chang , Tian Juan , He Xueqing , Chang Xiaona , Wang Guang , Liu Jia 
Published: May 2024

Abstract

Background: Dyslipidemia has been implicated in the pathogenesis of several diseases, including thyroid dysfunction and immune disorders. However, whether circulating lipids and long-term use of lipid-lowering drugs influence the development of autoimmune thyroid disease (AITD) remains unclear.
Methods: Two-sample and two-step Mendelian randomization (MR) studies were performed to assess the causal relationships between circulating lipids (LDL-C, TC, TG, and ApoB) and seven lipid-lowering drug targets (ApoB, CETP, HMGCR, LDLR, NPC1L1, PCSK9, and PPARα) with AITD. Mediation analyses were conducted to explore potential mediating factors.
Results: There was no clear causality between circulating lipids (ApoB, LDL-C, TC, and TG) and AITD (p > 0.05). ApoB inhibition is related to a reduced risk of autoimmune thyroiditis (AT) (OR = 0.462, p= 0.046), while PCSK9 inhibition is related to reduced Graves' disease (GD) risk (OR = 0. 551, p = 0.033). Moreover, PCSK9 inhibition (OR = 0.735, p = 0.003), LDLR inhibition (OR = 0.779, p = 0.027), and NPC1L1 inhibition (OR = 0.599, p = 0.016) reduced the risk of autoimmune hypothyroidism (AIH). Mediation analysis showed that NPC1L1 inhibition and PCSK9 inhibition exerted effects on AIH through IL-4 and FGF-19 levels. And the effect of PCSK9inhibition on GD through TNF-β levels.
Conclusions: There was no clear causality between circulating lipids (ApoB, LDL-C, TC, and TG) and AITD. Lipid-lowering drug target gene inhibitors reduced the AITD risk by modulating inflammatory factors.
Structural insights into transcription regulation of the global virulence factor PhoP from Mycobacterium tuberculosis
Authors: Shi Jing , Song Qian , Feng Zhenzhen , Wen Aijia , Liu Tianyu , Xu Liqiao , Ye Zonghang , Xu Simin , Gao Fei , Xiao Liuxiang , Zhu Jiapeng , Das Kalyan , Zhao Guo-Ping , Feng Yu , Lin Wei 
Published: May 2024

Abstract

Mycobacterium tuberculosis (Mtb), remaining as the leading cause of the worldwide threat Tuberculosis, relies heavily on its transcriptional reprogramming of diverse stress genes to swiftly adapt to adverse environments and ensure infections. The global virulence factor PhoP plays a pivotal role in coordinating transcription activation or repression of the essential phosphate-nitrogen metabolic remodeling genes. However, what defines PhoP to deferentially act as an activator or a repressor remains largely unexplored. Here, we determine one cryo-EM structure of Mtb RNAP-promoter open complex, three cryo-EM structures of PhoP-dependent transcription activation complexes (PhoP-TACs) consisting of Mtb RNA polymerase (RNAP), different number of PhoP molecules binding to different types of well-characterized consensus promoters, and one cryo-EM structure of Mtb PhoP-dependent transcription repression complex (PhoP-TRC) comprising of Mtb RNAP, PhoP, the nitrogen metabolism regulator GlnR and their co-regulated promoter. Structural comparisons reveal phosphorylation of PhoP is required for stabilization of PhoP-TACs, PhoP specifically recognizes promoters as novel tandem dimers and recruits RNAP through extensively interacting with its conserved β flap and σAR4 domains. Strikingly, the distinct promoter spacer length and PhoP-GlnR interactions in PhoP-TRC constrain the upstream DNA into a distinct topology and retain PhoP in a novel ‘dragging repression mode’. Collectively, these data highlight the dual regulatory mechanisms of PhoP-dependent transcription regulation in governing stress adaptation. These findings provide structural basis for developing potential anti-tuberculosis drugs and/or interventions.
Hormones and human capital
Authors: Taylor Leon , Korosteleva Anastassiya 
Published: May 2024

Abstract

Do hormones determine human capital by rewarding learning? The key prediction that the paper tests is that real gross domestic product, in total or per capita terms, which is indirectly produced by hormones, correlates positively with life expectancy. This would be because the biological justification of hormones is to enable the species to flourish. We develop a dynamic optimization model of how hormones affect life expectancy and test a reduced form of it with a panel dataset of 181 countries over the period from 2015 through 2020, yielding more than a thousand observations. Independent variables include the growth rate of GDP (which is a proxy for the growth rate of hormones), the share of youths in the national population (an alternative proxy for the growth rate of hormones), the share of middle-aged adults in the population (which measures family learning about health, which can increase life expectancy), the rate of enrollment in secondary schools among age-eligible youths (which measures general education), the female share of the population (which measures the impact on life expectancy of hormones that promote trust, such as oxytocin), the infant mortality rate, and country fixed effects. All data are from the World Development Indicators of the World Bank. We conclude that institutions may account for more of the economic impacts on life expectancy than hormones do.
Code: 10, 20, 30
Climate change in the Upper Paraguay Basin and hydrological impacts on the Pantanal
Authors: Ferreira Filipe Henrique Miranda , Cabral de Sousa Júnior Wilson , Bressiani Danielle , Manoel Mendes Filho Walter , Aparecido Gonçalves Demerval 
Published: May 2024

ABSTRACT
This study analyzed the impact of climate change on the hydrological conditions of the Upper Paraguay Basin, which has as its outlet the river channel in the municipality of Cáceres – Mato Grosso, Brazil, close to the plateau/Pantanal plain divide. Using the SWAT+ hydrological model and projections from the HADGEM and MIROC models, different flow scenarios were simulated under radiative concentration thresholds (RCP) 4.5 and 8.5. The results showed an average annual reduction of 44.07% in HADGEM 4.5, 51.00% in HADGEM 8.5, 37.35% in MIROC 4.5, and 39.12% in MIROC 8.5 inflows. The results are crucial for the management of water resources, the operation of the Paraguay-Paraná Waterway, and the resilience of the ecosystem, helping decision-making and management considering the predicted climate and hydrological changes.
Building resilience to multiple climate-change-related risks in QwaQwa using the community capitals approach
Authors: Muyambo Fumiso , Belle Johanes , Nyam Yong , Orimoloye Israel 
Published: May 2024

ABSTRACT
QwaQwa, in South Africa, experiences high exposure to multiple climate-change impacts. The area is particularly vulnerable to the effects of climate change. As such, this paper aims to assess community resilience, estimate the risk of multiple-climate change impacts in QwaQwa, and propose strategies to reduce risk and build resilience. Data were collected using a household survey and key informant interviews with a sample of 349 participants. An indicator method, based on the Community Capitals Framework, was used to measure resilience and estimate risk. The composite resilience indicators were weighted using principal component analysis. The Cronbach's alpha (α) test indicated a very good internal consistency in the scaled items. The results indicated that medium resilience to climate-change impacts in QwaQwa was mostly driven by access to all six capitals measured in this study: natural, human, social, financial, political, and infrastructural capitals. The multi-hazard risk estimate resulted in a very high index of 4.1. These results were validated at a stakeholder workshop. Strategies that use nature-based solutions, training and education for people of all ages, sectors and professions, and increased community and local government cooperation were deemed essential for boosting resilience and reducing disaster risks in the area.
Functional and financial analysis of an inclined step solar desalination using phase change nanomaterials
Authors: Mahal Ahmed , Al-Haideri Maysoon , Alkhouri Anas , Obaidullah Ahmad J. , Duan Meitao 
Published: May 2024

ABSTRACT
Recent decades have seen a shortage of water, which has led scientists to concentrate on solar desalination technologies. The present study examines the solar water desalination system with inclined steps, while considering various phase change materials (PCMs). The findings suggest that the incorporation of PCM generally enhances the productivity of the solar desalination system. Additionally, the combination of nanoparticles has been used to PCM, which is a popular technique utilized nowadays to improve the efficiency of these systems. The current investigation involves the transient modeling of a solar water desalination system, utilizing energy conservation equations. The equations were solved using the Runge–Kutta technique of the ODE23s order. The temperatures of the salt water, the absorbent plate of the glass cover, and the PCM were calculated at each time. Without a phase changer, the rate at which fresh water is produced is around 5.15 kg/m2·h. The corresponding mass flow rates of paraffin, n-PCM I, n-PCM III, n-PCM II, and stearic acid are 22.9, 28.9, 5.9, 11.9, and 73 kg/m2·h. PCMs, with the exception of stearic acid, exhibit similar energy efficiency up to an ambient temperature of around 29°. However, at temperatures over 29°, n-PCM II outperforms other PCM.
Analisa Rembesan Terhadap Terjadinya Piping pada Bendungan Cijurey Kabupaten Bogor Provinsi Jawa Barat
Authors: Denny Ahmad Fauzi  , Suwanto Marsudi  , Evi Nur Cahya  
Published: May 2024

Bendungan Cijurey merupakan bendungan tipe beton gravitasi atau tipe RCC dengan material beton yang memiliki nilai permeabilitas rendah. Secara struktur, tipe RCC memiliki lift joint yang rawan dilalui oleh air sehingga dapat menyebabkan rembesan. Bendungan ini terletak pada lapisan tanah yang mendominasi yaitu batulempung dan batupasir, dimana memiliki nilai permeabilitas yang berbeda dengan daya dukung yang rendah, selain itu debit rembesan yang terjadi akan memiliki pola yang berbeda. Analisa rembesan dan piping menggunakan bantuan software Geostudio SEEP/W. Hasil
analisa debit rembesan yang terjadi untuk kondisi normal (El. +286 m) yaitu 0,00196 m3 /dt dan untuk kondisi banjir 0,002 m3/dt dan untuk kondisi banjir (El. +288,28 m) yaitu 0,00076 m 3 /dt. Nilai faktor keamanan terhadap piping yaitu untuk kondisi normal (El. +286 m) yaitu 10,75 > 4 dan untuk kondisi muka air banjir (El. +288,28 m) yaitu 10,33 > 4, dapat dikatakan bendungan aman terhadap terjadinya piping.
Meta-Analysis and Systematic Review of the Role of Appendectomy in the Pathogenesis of Colorectal Cancer
Authors: Nezhad M.I. A. , Yabandeh N. P. 
Published: May 2024

Aim. Given the potential for physiological alterations in the gastrointestinal tract following appendix removal, which may influence carcinogenesis, we embarked on a systematic review and meta-analysis to explore the possible association between appendectomy and the subsequent risk of colorectal cancer (CRC).Methods. Our systematic investigation utilized sources including the Cochrane Library, Embase, PubMed, ClinicalTrials.gov, and Web of Science, covering research up to February 1, 2023. We assessed the impact of appendectomy on colorectal cancer, employing a random effects model to calculate the pooled hazard ratio (HR) for developing CRC post-appendectomy and its 95 % confidence interval (CI).Results. This review and meta-analysis incorporated a total of 10 studies, comprising 1,001,693 cases of appendectomy and 39,463 instances of CRC. The meta-analysis revealed a pooled HR of 1.04 (95 % CI: 1.0–1.08) for developing CRC following appendectomy. Notably, the HR for CRC development increased to 1.20 (95 % CI: 0.69–1.69) when considering only cases with more than 10 years of follow-up.Conclusion. The findings indicate a marginally increased risk of colorectal cancer in cases without a specified follow-up period. However, this elevated risk did not persist over the long term (exceeding 10 years). The heterogeneity of the included studies appears to have influenced our results. Nevertheless, it is advisable for physicians to weigh the potential benefits of alternative therapies and consider the future complications that may arise from an unnecessary appendectomy.
Accounting on Czech Noble Estates during the Agricultural Revolution
Authors: Slavíčková Pavla 
Published: May 2024

ABSTRACT
The paper follows Edwards’ (2011) findings published in the Accounting Historians Journal concerning the persistence of a simpler style of bookkeeping in practice instead of double-entry accounting, even in the period of growth of the capitalist mode of economy. The article supports the conclusion about the use of accounting for managerial purposes by examining the content of treatises written by members of the Puteani family, who fundamentally influenced accounting on noble estates in the Czech Lands during the agricultural revolution (late 1700s–1870s). The paper describes the structure and essence of cameralist accounting, which replaced the older bookkeeping style and was preferred over double-entry accounting by landowners. It demonstrates that cameralist accounting became an integrated part of the reforms applied at Czech noble estates during the agriculture revolution due to its objectives, which fully corresponded with the purposes of the owners for the management and development of their estates.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: N83; N13; M41; O16.
Evaluation of anchorage loss after en masse retraction in orthodontic patients with maxillary protrusion using friction vs frictionless mechanics: randomized clinical trial
Authors: Attia Amr Mahmoud , Shibl Leena A. , Dehis Heba M. , Mostafa Yehya A. , El-beialy Amr R. 
Published: May 2024

ABSTRACT

Objectives
To evaluate anchorage loss after en masse retraction in bimaxillary dentoalveolar protrusion patients using friction vs frictionless mechanics.

Materials and Methods
Thirty patients with bimaxillary dentoalveolar protrusion needing extraction of upper first premolars and en masse retraction with maximum anchorage were included in this two-arm, parallel, single-center, single-blinded randomized clinical trial with a 1:1 allocation ratio using fully sealed opaque envelopes. Friction group retraction utilized elastomeric power chain between miniscrews and hooks crimped mesial to upper canines on 17 × 25 stainless steel archwire. Frictionless group used customized T-loop springs loading upper first molars indirectly anchored to miniscrews. Activation was every 4 weeks until full retraction. The primary outcome assessed was anchorage loss evaluated at cusp tip and root apex of the first molar. First molar rotation, incisor tip and torque, and root resorption of anterior teeth were evaluated on digital models and cone beam computed tomography taken before and after space closure.

Results
Anchorage loss at crown of first molar was significantly more in frictionless group by 2.1 mm (95% CI = −0.4 to 3.5), (P = .014), while there was no significant difference in anchorage loss at root apex between groups. Significant mesial in molar rotation of 6.672° (95% CI = 12.2–21.2), (P = 0.02) was greater in the frictionless group. Both groups showed comparable tip, torque, and root resorption values. No severe harms were reported. There was mild gingival overgrowth and inflammation in the frictionless group due to T-loop irritation.

Conclusions
Extra anchorage considerations are needed during en masse retraction when frictionless mechanics is implemented as higher anchorage loss and molar rotation were detected. No difference in tip, torque, and root resorption was observed.
Simulation Research on Logistics Distribution Path Based on Colony Intelligence Optimisation
Authors: Liu Xiaoling , Xu Jing 
Published: May 2024

Abstract
In light of the growing emphasis on “logistics integration,” this paper contends that the logistics network system requires comprehensive integration and optimization. We propose the use of the Bacterial Foraging Optimization (BFO) algorithm to enhance the Vehicle Routing Problem (VRP). The penalty function method is employed to direct the BFO algorithm in identifying the optimal vehicle path encoding and to improve the convergence operations for logistics distribution. This study analyzes the fundamental characteristic elements of the VRP, introduces a basic model for the VRP, and develops a logistics distribution path optimization model that minimizes the total cost by thoroughly considering the expenses associated with cold chain low-carbon logistics distribution. A simulation environment is established, and algorithm parameters are set to determine the optimal solutions for both the BFO and the Improved BFO (IBFO) algorithms in the test function. An example is selected for practical application, wherein the design of the distribution center and points is carried out, and the colony intelligence optimization algorithm is applied to simulate the logistics and distribution paths. Combined with the specific case of cold chain distribution of food, the optimization of the cold chain logistics distribution path is solved. In the case study, when the carbon penalty coefficient is ε = 15, the optimal logistics and distribution site selection program is Guangxi and Guizhou, and the total cost of the supply chain is 16,363,365.92 yuan. At this time, the supply chain cost is optimal. Compared with the carbon penalty coefficient ε = 20, the economic cost increased by 70152.24 yuan, but the carbon emission decreased by 1890.9 kg. The optimization of logistics and distribution processes encourages enterprises to develop strategies that promote low carbon and environmental protection and achieve better economic and ecological outcomes.
Identification and Validation of New Reference Genes for Normalization of Gene Expression in Flower and Berry Developmental Stages of Interspecific Grape Hybrid V. vinifera (L.) × V. labrusca (L.)
Authors: Chavan Siddhi , Khatal Anil , Phalake Satish , Tetali Sujata , Patil Ravindra 
Published: May 2024

Abstract
In quantitative reverse transcription polymerase chain reaction (qRT-PCR), normalizing target gene expression using a reference gene is an indispensable step to control the variability of RNA extraction yield, RNA integrity, reverse transcription efficiency, and PCR amplification. In the present study, we identified candidate reference genes with stable expression during grapes’ flowering and berry development stages. Ten genes, including ACT, CYP5, RLI, TUB, UBC, UBC17, UBC60, UFD1, VAG, and ZNF with relatively stable expression, were selected based on RNAseq data generated earlier in grape hybrid ‘ARI 516’. The expression of these candidate genes was tested at different stages of flowering and grape berry development. Five different algorithms such as RefFinder, geNorm, NormFinder, BestKeeper, and the comparative ΔCq method were used to test the expression stability of candidate genes. A comprehensive ranking obtained by RefFinder showed that UBC17, RLI, and ZNF were the most stable reference genes during flower and berry development stages. UBC17, RLI, and ZNF were calibrators to normalize the expression of VvAGL11 as a target gene to validate the worthiness of identified reference genes. The result demonstrated that newly identified reference genes could be successfully used to normalize the expression of the target gene accurately. These reference genes will provide more choices for selecting appropriate reference genes to normalize gene expression in grapes.
The association of rationed nursing care and the level of teamwork in acute care setting: a cross-sectional study
Authors: Kohanová Dominika , Solgajová Andrea , Bartoníčková Daniela 
Published: May 2024

Abstract

Aim. To explore the association of rationed nursing care and the level of teamwork from the perspective of nurses working in an acute care setting in Slovakia.

Material and methods. The descriptive cross-sectional study was conducted between November 2022 and February 2023. Data collection was carried out using a set of questionnaires that involved the Basel Extent of Rationing of Nursing Care – Revised (BERNCA-R) and the Nursing Teamwork Survey (NTS) to explore the level of teamwork. The sample consisted of 206 nurses from three district hospitals from Slovakia.

Results. The mean score of the BERNCA-R was 2.11 (SD = 0.65) and for NTS, it was 3.64 (SD = 0.35). A statistically significant association was found between rationed nursing care and the level of teamwork, more specifically, Trust (r = -0.583), Team orientation (r = -0.381), Backup (r = -0.657), Shared mental model (r = -0.768), and Team leader (r = -0.535) and the overall score of the NTS (r = -0.174).

Conclusions. These findings underscore the importance of addressing the phenomenon of rationed nursing care among registered and practical nurses to foster better teamwork and enhance patient care outcomes in acute care settings.