bluuebunny/crossref_metadata_2025_split huggingface dataset:
A nomogram for predicting the probability of femoral head collapse in convalescent SARS patients with glucocorticoid-induced osteonecrosis of the femoral head: an 18-year population-based retrospective cohort study
Authors: Qu Rundong , Gao Fuqiang , Sun Wei , Li Zirong 
Published: May 2024

BackgroundThis study aimed to develop a nomogram capable of predicting the probability of femoral head collapse based on an 18-year follow-up cohort of convalescent severe acute respiratory syndrome (SARS) patients with glucocorticoid-induced osteonecrosis of the femoral head (ONFH).MethodsData on the natural history of 120 patients (205 hips) who underwent glucocorticoid-induced ONFH at China-Japan Friendship Hospital (CJFH) in 2003 were retrospectively collected. Follow-up was conducted from June 2003 to October 2021. A nomogram was developed in a training cohort and validated in another cohort.ResultsA total of 205 hips were included for analysis, with 143 hips in the training cohorts and 62 hips in the validation cohorts. After 18 years of follow-up, 53 femoral heads collapsed, while 152 femoral heads spontaneously repaired to some extent (necrotic areas reduced or vanished). Following multivariate regression analysis, the Association Research Circulation Osseous (ARCO) staging, necrosis index (NI), and CJFH Classification were entered into the nomogram. The nomogram showed robust discrimination, with an AUC of 0.907 (95% CI: 0.85–0.96). The calibration curves showed an agreement between the probability as predicted by the nomogram and the actual probability. Application of the nomogram in the validation cohort also yielded good discrimination (AUC, 0.876, 95% CI: 0.7751–0.9761) and calibration.ConclusionThe nomogram successfully predicted femoral head collapse in glucocorticoid-induced ONFH. With the nomogram, the prognosis for an individual patient with glucocorticoid-induced ONFH can be determined, which can lead to a rational therapeutic choice.
PROGRAM PEMBELAJARAN DAN PEMBERDAYAAN KEPADA MASYARAKAT DI KAMPUNG KAMNO SARI, PAPUA SELATAN
Authors: Simangunsong Ika trisni , Irsyam Muhammad , Ratna Sari Puji , Jamlean Veronika 
Published: May 2024

Kegiatan pengabdian ini merupakan aktualisasi dari program KKN. KKN menjadi perwujudan pemberdayaan sumber daya manusia (SDM) dalam kurikulum pendidikan tinggi. Interaksi mahasiswa di masyarakat sebagai kelas kontekstual untuk belajar, dan wahana pendekatan melalui lintas keilmuwan yang bermanfaat bagi sasaran masyarakat. Tim terdiri atas 10 orang mahasiswa, dan 1 orang dosen. Pelaksanaan selama 30 hari di Kampung Kamno Sari, Distrik Jagebob, Provinsi Papua Selatan. Metode pengabdian dilakukan dengan tahapan observasi, perencanaan, pelaksanaan, dan evaluasi. Observasi dilakukan dengan tehnik wawancara dan pengamatan langsung. Perencanaan dilakukan setelah diperoleh masalah yang dapat diselesaikan oleh tim dengan melihat urgensi, latar belakang rumpun keilmuwan, dan kemampuan tim. Pelakasanaan kegiatan meliputi program pembelajaran komputer dasar bagi anak sekolah, pemberdayaan masyarakat dalam pembuatan naget, serta pembuatan papan identitas jalan. Evaluasi program diperoleh dengan mendapatkan masukan dari kepala desa, dan masyarakat sebagai bahan masukan bagi mahasiswa, dosen, dan juga Universitas. Dana program bersumber dari DIPA Universitas Musamus Tahun Anggaran 2024. Program ini disambut baik oleh pemerintah desa, dan masyarakat. Kebermanfaatannya dapat dirasakan secara langsung oleh masyarakat.
الرقابة القضائية على تنفيذ حكم التحكيم في منازعات العقود الإدارية (دراسة مقارنة)
Authors: العرسان زياد أحمد 
Published: May 2024

أصبح التحكيم النظام القانوني البديل لحسم منازعات العقود الإدارية, إلا أن ذلك لا يعني انفصاله بشكل نهائي عن قضاء الدولة, حيث يوجد بينهما علاقة وثيقة ولا سيما فيما يمارسه قضاء الدولة على التحكيم من رقابة على تنفيذ حكم التحكيم في منازعات هذه العقود, وتبين لنا مشروعية الرقابة على تنفيذ حكم التحكيم لعدة مبررات لعل أهمها أن هذا الحكم عمل إنساني يرد عليه الغلط فلا بد من تمكين الخصم من تفادي الضرر بفرض هذه الرقابة عليه بقصد إصلاحه, كما تعرضنا لبحث صور الرقابة القضائية الشكلية والموضوعية وأيدنا أن تكون هذه الرقابة بصورتيها جدية وفعالة وليست محدودة على الفحص الظاهري لتنفيذ حكم التحكيم, وبحثنا حدود الرقابة القضائية في مرحلة تنفيذ حكم التحكيم, وظهر لنا أن المشرع الفرنسي والمصري والسوري منح الاختصاص في الرقابة على تنفيذ حكم التحكيم للقضاء الإداري لأنه الأقدر على ممارسة هذه الرقابة من القضاء العادي, ومن أجل استصدار أمر تنفيذ حكم التحكيم اجمعت التشريعات على أن لا يكون هذا الحكم مخالفاً للنظام العام, وأخيراً تبين لنا أنه يجوز في فرنسا ومصر الطعن في القرار الصادر برفض تنفيذ حكم التحكيم، أما فيما يتعلق بالقرار الصادر بتنفيذ هذا الحكم، فقد لم يجز المشرع الفرنسي ذلك في فرنسا أما في الخارج أجاز ذلك بالاستئناف،, أما المشرع المصري فلم يجز ذلك مطلقاً. أما في التشريع السوري فلم يسمح الاجتهاد بالطعن بإكساء صيغة التنفيذ لحكم المحكمين وانتقدنا ذلك واقترحنا السماح بالطعن به لكونه حكماً قضائياً من كل الوجوه.
Modelling Definition in Mechanical Engineering Texts Viewed from SFL
Authors: Khorina Mulyati 
Published: May 2024

Introductory textbooks of undergraduate students contain commonly accommodate numerous technical terms which are commonly in form of abstract nouns. The technical terms naturally represent the knowledge of the discipline which serve to build the knowledge of the field. Unfortunately, the technical terms tend to use abstract words which require definition to understand them. Hence, understanding the construction of a definition will help the learners of the field understand the texts. Therefore, the purpose of this study was to investigate the construction of definition appearing in technical terms appearing in disciplinary texts, like mechanical engineering textbooks. The qualitative data were collected from introductory textbooks of mechanical engineering. The results of analysis using Systemic Functional Linguistics (SFL) reveal several findings. First, definition is realized by clause complex consisting of main clause and subordinate clause. Consequently, the clause has hypotactic relation and semantic one. The main clause is realized by intensive clause with relational process realized by some lexical verbs. Whereas subordinate clause is realized by non-finite or finite clause of possessive or circumstantial clause. The subordinate clause semantically serves as elaboration of the Thing in the main clause. The elaboration can be formed as function/properties/duration/condition/results which make the Thing in the main clause definite. Based on these findings, definition can be formulated as intensive clause (main clause) + possessive/circumstantial clause of non-finite/finite clause (subordinate clause). The findings also have implication on ESP or EAP learning which can help learners in academic reading and writing.
DAPATKAH PROFITABILITAS MEMPENGARUHI HARGA SAHAM?
Authors: Putri Ferica Christinawati 
Published: May 2024

Penelitian ini bertujuan untuk mengetahui pengaruh rasio profitabilitas yang terdiri dari : ROA, ROE, NPM, GPM dan EPS terhadap harga saham.Â Penelitian ini menggunakan data sekunder melalui sumber data dan bursa efek indonesia yang telah dipublikasikan oleh perusahaan manufaktur sebanyak 117 perusahaan dalam Penelitian ini dilakukan dalam jangka waktu penelitian selama tahun 2016-2020. Teknik analisis dalam penelitian ini menggunakan Structural Equation Modelling-Partial Least Square (SEM-PLS). Hasil penelitian menyatakan bahwa ROA dan EPS berpengaruh Â positif terhadap harga saham sedangkan ROE, NPM dan GPM tidak berpengaruh positif terhadap harga saham. Â
Deposition of a polymer thin film on a silver surface for surface plasmon sensing
Authors: Abe Akinari , Chakraborty Ipsita , Matsubayashi Daiki , Noguchi Tsuyoshi , Okino Akitoshi , Kano Hiroshi 
Published: May 2024

Abstract
We report a deposition method of a polymer thin film on the silver surface of a surface plasmon sensor for preventing sensitivity degradation in refractive index measurements due to the poor chemical stability of the silver. The deposition of a poly(methyl methacrylate) thin film with a ∼15 nm thickness was conducted by employing a spin coating technique along with a hydrophilicity enhancement of the silver surface using an atmospheric low-temperature plasma treatment. We experimentally verified the thickness by measuring the propagation constant of the surface plasmon. The measured propagation constants that showed the standard deviation at the order of 10−4 indicated microscopical uniformity. Furthermore, the reproducibility of thickness was experimentally verified.
PENINGKATAN KETERAMPILAN MENGOLAH PANGAN LOKAL MELALUI KEGIATAN BINA GIZI DI WILAYAH LOKUS STUNTING DESA SUKAJADI KECAMATAN CISAYONG KABUPATEN TASIKMALAYA
Authors: Sumarto  , Nuraeni Irma , Karimah Ima , Setiawati Dina , Hadiningsih Naning 
Published: May 2024

Permasalahan stunting di wilayah lokus stunting di Desa Sukajadi, Kecamatan Cisayong, Kabupaten Tasikmalaya masih tinggi. Salah satu faktor langsung penyebab stunting pada balita adalah asupan gizi dan faktor tidak langsung adalah penghasilan atau ekonomi keluarga. Sehingga perlu upaya terpadu dengan salah satunya melalui pendidikan gizi untuk meningkatkan pengetahuan dan keterampilan para kader calon pengusaha dalam mengolah pangan lokal yang ada di sekitarnya. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan dan keterampilan sasaran dalam mengolah pangan lokal berbasis sayuran. Metode intervensi adalah dengan pendidikan gizi melalui ceramah dan demonstrasi. Perubahan pengetahuan diukur melalui pre-test dan post-test. Variabel keterampilan diukur melalui observasi. Hasil pengabdian kepada masyarakat menunjukkan bahwa pengetahuan peserta tidak berubah dengan nilai yang baik yaitu 90. Peserta meningkatkan keterampilannya dalam mengolah sistik dari bahan baku sayur yaitu wortel, ubi ungu, dan bayam. Perlu dilakukan kegiatan lebih lanjut dalam pengembangan usaha melalui pendampingan perolehan izin edar dan survei pasar.
Corundum in Sulfide Ore at the Thompson Mine, Manitoba, Canada: An Unusual Occurrence of Cr- and Ni-Bearing Corundum
Authors: Belley Philippe M. , Onodenalore Ofure C. , Bleeker Wouter 
Published: May 2024

Abstract
A novel type of corundum host environment is described from the Thompson Mine, northern Manitoba, where corundum occurs within a high-grade metamorphic reaction zone between boudinaged metaperidotite bodies, sulfide ore, and Al-rich pelitic schist of the Pipe Formation (Ospwagan Group). Zoned corundum porphyroblasts, up to 20 mm across, contain coevally formed sulfide inclusions, zircon, rutile, abundant exsolved rutile needles, and secondary sulfide inclusions formed within fractures. Retrograde alteration products of corundum include greenish muscovite (in contact with the schist) and diaspore (in contact with sulfides). The median concentrations of trace elements in Thompson corundum are as follows (in µg/g): 119 Mg, 1720 Ti, 69.9 V, 390 Cr, 8.2 Mn, 1924 Fe, 9.1 Ni, and 106 Ga. The geochemical signature of Thompson corundum (enrichment in Fe, Cr, and Ni) resembles that of ruby in other metamorphic and metasomatic mafic-ultramafic-hosted deposits, and the Cr concentration is comparable to the low range of rubies. Thompson corundum contains high Ni concentrations relative to most Cr-enriched corundum occurrences, a result of formation in an exceptionally Ni-rich environment. The high abundance of exsolved rutile inclusions imparts a dominantly brownish-gray color to the corundum, which precludes it from being of gem quality. Chromium-bearing corundum has been suggested as a possible indicator mineral for metamorphosed massive sulfide deposits, however, it is an indirect indicator that risks yielding false positives. Further investigation into Ni concentrations in corundum, a potential indicator of formation in a Ni-rich environment, is recommended.
Units of fibrinolytic system in mice with urokinase gene knockout in presence of growing B16/F10 melanoma
Authors: Frantsiyants E. M. , Bandovkina V. A. , Surikova E. I. , Kaplieva I. V. , Pogorelova Yu. A. , Neskubina I. V. , Trepitaki L. K. , Cheryarina N. D. , Ushakova N. D. , Ishonina O. G. , Gusareva M. A. , Udalenkova I. A. 
Published: May 2024

Purpose of the study. Was to reveal the effect of urokinase gene knockout in male and female mice with transplanted B16/F10 melanoma on the functions of the fibrinolytic system units.Materials and methods. Male and female mice were used: main group with genetically modified mice C57BL/6-Plautm1. 1Bug – ThisPlauGFDhu/GFDhu (uPA-/-); control group with С57Bl/6 (uPA+/+) mice. B16/F10 melanoma was transplanted by the standard methods to the animals, and levels of plasminogen (PG), plasmin (PAP), urokinase receptor uPAR, content (AG) and activity (act) of uPA, t-P A and PAI-I were measured with ELISA (Cussabio, China) in 10 % tumor homogenates and peritumoral area after 3 weeks of tumor growth.Results. The activity and levels of urokinase in intact uPA-/- animals were significantly (by 100–860 times) inhibited, compared to uPA+/+, but uPAR levels were unchanged in females and were 1.9 times lower in males. PAP levels in uPA-/- mice were 2.1–4.2 times higher than in uPA+/+ animals. The growth of B16/F10 melanoma in uPA-/- mice was slower and metastasizing was suppressed, but their survival was not improved. The dynamics of changes in components of the fibrinolytic system in presence of melanoma growth differed in uPA-/- mice, compared to uPA+/+ animals: PAP levels in tumor samples decreased by over 2 times, uPA levels and activity were not increased, PAI was practically unchanged, but activity of t-P A elevated by 3.8–8.2 times, as well as in uPA+/+ mice.Conclusion. Despite the suppression of the growth and metastasis of the primary tumor nodes in uPA-/- mice, their average survival was not improved, which indicates that the mechanisms of tumor are complex and there are alternative biological pathways supporting melanoma to survive in conditions of the urokinase gene knockout.
Hypoxia effect on proliferative activity of cells in orthotopic xenograft of hepatocellular carcinoma of the liver in the experiment
Authors: Kecheryukova T. M. , Trifanov V. S. , Shulg A. A. , Goncharova A. S. , Gurova S. V. , Ulyanova E. P. , Maksimov A. Yu. 
Published: May 2024

Purpose of the study. The purpose of this research was to investigate the effect of in vivo hypoxic conditions on the proliferative potential of HepG2 liver cancer cells.Materials and methods. Human liver cancer cells of the HepG2 line have been cultured. The HepG2 cell suspension was injected subcutaneously into mice in an amount of 5 × 106 to obtain a xenograft. Tumor nodes that had reached the required size were divided into fragments and transplanted into the orthotopic site. Balb/c nude mice with implanted HepG2 liver cancer xenograft were used in this experiment. The mice with tumor implanted in the liver were divided into two groups, intact and hypoxic. Mice from the second group underwent liver blood flow reduction by occlusion of the portal triad for 20 minutes. Tumor nodes were extracted for histological and immunohistochemical staining for proliferation marker Ki-67 on the 4th day after the procedures. The proportion of positively stained cells was calculated, and the results were statistically analyzed using the Statistica 10.0 software.Results. Orthotopic models of liver cancer in Balb/c Nude mice were obtained. Histological and immunohistochemical studies were carried out. Histological analysis showed that hepatocellular carcinoma is characterized by an average degree of differentiation. In the tissues of these xenografts, by using immunohistochemical analysis for the proliferation marker Ki-67, it was possible to identify statistically significant differences between the two groups, i.e. intact and the one with reduction of blood flow. The proportion of immunopositive cells was 65 [65–70] % and 19 [15–25] %, respectively.Conclusion. A tendency to decreased proliferative activity of tumor cells after hepatic blood flow reduction, i.e. hypoxia exposure, was demonstrated. Our data indicate that the proliferative activity of tumor cells is directly related to the microenvironment, and to the hypoxic environment in particular. Further study of the effect of hypoxia on the processes of growth and development of malignant tumors may contribute to a deeper understanding of the biological features of tumors and their treatment.
Dynamics of saliva cytokine levels during intraoperative photodynamic therapy in patients with locally advanced oral cancer
Authors: Komarova E. Yu. , Zlatnik E. Yu. , Komarova E. F. , Novikova I. A. , Dzhenkova E. A. , Engibaryan M. A. , Sagakyants A. B. , Pozdnyakova V. V. , Rozenko L. Ya. 
Published: May 2024

Purpose of the study. Assessment of the level of certain cytokines in the saliva of patients with primary locally advanced cancer of the oral mucosa in addition to surgical treatment with intraoperative PDT (IPDT).Patients and methods. Patients with primary locally advanced cancer of the oral mucosa T3-4aN0-2M0 were divided into 2 groups: the main group (30 patients) underwent radical tumor removal supplemented with IPDT and the control group (30 patients) without addition. IPDT was performed using Latus-T (farah) and a chlorin E6 photosensitizer. Cytokine levels were determined in unstimulated whole saliva the day before, on the 3rd and on the 7th day after the operation by the ELISA multiplex analysis method.Results. A similar dynamic of the cytokine profile of patients of both groups was shown: on the 3rd day after surgery, the levels of G-CSF, IL-6, MIP-1β increased, and GM-CSF and IFN-γ decreased compared with baseline values. On the 7th day, the dynamics of G-CSF, GM-CSF, IL-6 persisted, while IL-8, IL-10, IL-12 changed to the opposite.Intergroup differences were revealed in the level of IL-1β - on day 3, an increase in the main group and a decrease in the control group. The level of IL-7 on day 7 decreased sharply in the control group and increased statistically significantly in patients receiving IPDT. The main group showed a 4.8-fold increase in IL-8 on day 3 and its 3.6-fold drop on day 7 with the opposite dynamics in the control group. The TNF-α level increased only in the main group on day 7, and in the control group it decreased by 3 and recovered on day 7. On day 3, the MCP-1 level increased in the main group and decreased in the control group. The level of IL-17 in the main group increased on the 3rd day with a further decrease below the baseline, and in the control group it decreased on the 3rd day, followed by a recovery on the 7th. An increase in IL-5 and IL-13 levels on day 3 was noted only in the control group, however, the level of IL-5 in both study periods in the main group was lower than in the control group.Conclusion. IPDT in patients with primary locally advanced oral cancer causes changes in the cytokine composition of saliva during the first week after surgery, some of which can be associated with an elongation of the relapse-free period in such patients.
PENGEMBANGAN POTENSI KEARIFAN LOKAL YANG MENDUKUNG PARIWISATA DI KAMPUNG TUA PATAM LESTARI KELURAHAN PATAM LESTARI KECAMATAN SEKUPANG KOTA BATAM
Authors: Fairuzzabadi  , Herman Suranta Ginting  , Yuanita FD Sidabutar  , Malahayati Rusli Bintang  
Published: May 2024

Pariwisata merupakan salah satu sektor pembangunan di bidang ekonomi. Sektor pariwisata di Indonesia saat ini diandalkan sebagai sektor alternatif yang diharapkan dapat memberikan kontribusi terhadap pertumbuhan perekonomian Negara. Pengembangan sektor pariwisata menjadi salah satu program unggulan dalam usaha pembangunan daerah yang juga diharapkan dapat memberikan konstribusi terhadap penerimaan Pendapatan Asli Daerah (PAD) dan menciptakan lapangan kerja di daerah. Pengembangan pariwisata di daerah juga dapat dilakukan dengan mengembangkan potensi-potensi kearifan lokal yang terdapat di daerah tersebut. Potensi kearifan lokal yang mendukung pengembangan pariwisata di daerah menjadi bagian dari produk kreativitas manusia yang juga memiliki nilai ekonomi. Tujuan penelitian adalah menganalisis potensi-potensi kearifan lokal yang dapat dimanfaatkan untuk pengembangan pariwisata berbasis kearifan lokal di Kota Batam, khususnya di wilayah Kampung Tua Patam Lestari yang dapat dikemas dalam bentuk wisata kuliner, wisata bahari dan wisata budaya. Metode penelitian yang digunakan adalah analisis diskriftif yang mendeskripsikan temuan-temuan penelitian berdasarkan data-data yang dianalisis dan kemudian dilakukan penelitian secara mendetail. Sedangkan metode analisa yang digunakan adalah analisa Sternght, Weakness, Opportunity and Threats (SWOT). Analisa SWOT digunakan untuk menganalisa potensi dan permasalahan yang mendukung pengembangan pariwisata berbasis kearifan lokal di Kampung Tua Patam Lestari. Penelitian ini dilakukan untuk menghasilkan sebuah model alternatif yang dapat digunakan dalam pengembangan pariwisata di wilayah Kota Batam. Potensi kearifan lokal di Kampung Tua Patam Lestari dapat dikembangkan dan dijadikan peluang untuk dapat meningkatkan kesejahteraan masyarakat sekitarnya, juga bermanfaat untuk melestarikan budaya dan ciri khas melayu di Kota Batam.
Konseling Islam Melalui Terapi Berpikir Positif untuk Mengelola Stres Ketua Himpunan dan Organisasi
Authors: Rasyadi Ahmad Fitra , Wardana Mustahar Ali 
Published: May 2024

This research aims to determine the process and results of Islamic Counseling through Positive Thinking Therapy to Manage Stress for the General Chair of HMP and UKM at the Faculty of Da'wah and Communication (FDK) Islamic State University of Sunan Ampel Surabaya (UINSA). This problem was answered by researchers using qualitative research methods by case study analysis general chairs of HMP and UKM at FDK UINSA. The analysis used observation and interview techniques. The counseling process used cognitive restructuring to manage stress of the general chairs of HMP and UKM by changing negative perceptions into positive using thought records. The results of positive thinking therapy showed that there was a change in the connotation of negative thoughts which have been successfully transferred into positive thoughts by the counselee untill can suppress stress due to problems that arise and are felt by the counselee.
Detecting the Early Optical Flashes of Gamma-Ray Bursts with Small Telescope Arrays
Authors: Sadeh Iftach 
Published: May 2024

Abstract
We present an observational approach for the independent detection of the early optical emission of long gamma-ray bursts (GRBs). For this purpose, we explore the potential of the Large Array Survey Telescope (LAST). This array of small optical telescopes can be used to scan a wide region of the sky, and to focus on a smaller field of view with increased sensitivity, as needed. The modularity of the array facilitates dynamic scanning of multiple fields, by shifting telescope pointing directions with high cadence. This can significantly increase the effective sky-coverage of a blind survey on short timescales. For events associated with gamma-ray counterparts, the valuable early time data can supplement high-energy observations. Regardless of gamma-ray association, detections can potentially be used to explore various phenomena associated with GRBs, such as orphan afterglows; dirty fireballs; and choked jets. We simulate a sample of GRBs and their respective optical signals at early times. After accounting for dynamic cadence, the light curves are given as input to a machine-learning classifier, used to identify astrophysical transients. We find that, by dedicating half of an LAST array to a blind search, one would expect to independently detect 7–11 GRBs yr–1, corresponding to an approximate intrinsic event rate of 0.12 deg–2 yr–1.