bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dialogue in the Dark Malaysia: reimagining an inclusive society through social innovation
Authors: Chong Yit Sean , Teh Yong Yuan 
Published: May 2024

Research methodology
This case was developed via primary data collected from personal (one to one) interview with the CEO and founder of Dialogue in the Dark Malaysia (Dialogue Malaysia), Stevens Chan. With Stevens’ contact, the authors also conducted personal interviews with Kaye Chan (co-founder and wife of Stevens Chan), Lynn Foo (project manager since inception until early 2022) and Dr Foo Yin Fah (academic researcher in social entrepreneurship and advisor for Dialogue Malaysia). Secondary data included reports on visually impaired context in Malaysia, Dialogue Malaysia’s annual reports and online articles. Prior to the primary data collection, the authors obtained ethics approval from the University Human Ethics Committee (Project ID: 35461).

Case overview/synopsis
This case narrative focuses on Stevens Chan, a blind social entrepreneur who champions the empowerment of the disabled and marginalised community. Through a social franchising model, Stevens founded Dialogue in the Dark Malaysia in 2012. As a social start-up, Stevens showcases the strengths of blind and visually impaired individuals through transformative experiential encounters and reimagining future possibilities. Although there are constant challenges in securing financial and human capital, Stevens never lacks psychological capital, characterised by hope, self-efficacy, optimism and resilience. His vision is to educate society on the power of empathy (and not sympathy) and to create a holistic experience of celebrating diversity and inclusion through an innovative discovery centre, where the elderly and the disabled community (including the deaf, mute and those with mobility issues) share their lives with the public through fun activities. However, the future of this social enterprise is uncertain, and this case invites participants to embark on this journey with Stevens to uncover future pathways for growth and social impact.

Complexity academic level
The case is tailored for higher level undergraduates and entry-level and mid-level managers of executive education programs.
Implementing Lean 4.0: a review of case studies in pharmaceutical industry transformation
Authors: Tetteh-Caesar Michelle Grace , Gupta Sumit , Salonitis Konstantinos , Jagtap Sandeep 
Published: May 2024

PurposeThe purpose of this systematic review is to critically analyze pharmaceutical industry case studies on the implementation of Lean 4.0 methodologies to synthesize key lessons, benefits and best practices. The goal is to inform decisions and guide investments in related technologies for enhancing quality, compliance, efficiency and responsiveness across production and supply chain processes.Design/methodology/approachThe article utilized a systematic literature review (SLR) methodology following five phases: formulating research questions, locating relevant articles, selecting and evaluating articles, analyzing and synthesizing findings and reporting results. The SLR aimed to critically analyze pharmaceutical industry case studies on Lean 4.0 implementation to synthesize key lessons, benefits and best practices.FindingsKey findings reveal recurrent efficiency gains, obstacles around legacy system integration and data governance as well as necessary operator training investments alongside technological upgrades. On average, quality assurance reliability improved by over 50%, while inventory waste declined by 57% based on quantified metrics across documented initiatives synthesizing robotics, sensors and analytics.Research limitations/implicationsAs a comprehensive literature review, findings depend on available documented implementations within the search period rather than direct case evaluations. Reporting bias may also skew toward more successful accounts.Practical implicationsSynthesized implementation patterns, performance outcomes and concealed pitfalls provide pharmaceutical leaders with an evidence-based reference guide aiding adoption strategy development, resource planning and workforce transitioning crucial for Lean 4.0 assimilation.Originality/valueThis systematic assessment of pharmaceutical Lean 4.0 adoption offers an unprecedented perspective into the real-world issues, dependencies and modifications necessary for successful integration, absent from conceptual projections or isolated case studies alone until now.
Deconstructing digital nomads: are they the last frontiers of the post-tourist?
Authors: Kaya Sayarı Burcu , Coşkun İnci Oya 
Published: May 2024

PurposeThis research aims to scrutinize the dwelling of digital nomads in postmodernism’s social, cultural and political context and to illuminate their post-tourist characteristics.Design/methodology/approachUsing a conceptual approach and sociological considerations, the study closely investigates the characteristics of digital nomads and offers a postmodernist ontological, epistemological and methodological stance.FindingsThe study highlights the ambiguity of the concepts of digital nomadism and tourism. Furthermore, since every digital nomad is a potential tourist with a work-leisure balance, it points out the need to grasp tourism and work from a different perspective than the dichotomy of modernism.Research limitations/implicationsThe postmodernist perspective offers a fruitful approach to illuminate the social conditions in which digital nomads dwell and concomitantly encompasses the tourist and nomad by rejecting dichotomies. The study also points out the need to place the agency of digital nomads in a broader context and analyze these mobilities from local and global interactions in addition to the nomads' point of view.Originality/valueThis study provides a new perspective on the relationship between digital nomads, postmodern conditions and their role as post-tourists.
Equivalent mating system parameters in post‐mining and undisturbed native plant populations confirms restitution of bird‐pollinator function
Authors: Krauss Siegfried , Anthony Janet , Lapenzee Suzanne , Ritchie Alison , Elliott Carole , Dobrowolski Mark P. , Standish Rachel 
Published: May 2024

Abstract

The restoration of diverse self‐sustaining ecosystems requires re‐establishment of functional interactions among species. For plant communities, pollinators are usually essential for pollination, seed set and seed quality. A common assumption in ecological restoration for plants pollinated by animals is one of ‘build it and they will come’, which is rarely tested. Beyond seed set, there may be negative genetic consequences for seed quality if pollinators and their behaviour do not reflect those in reference populations.

Here, we conduct an ecological genetic assessment of seed quality via mating system parameters in Lambertia multiflora (Proteaceae), a species dependent on nectar‐feeding birds for pollination. Four populations of L. multiflora in disturbed sites that were rehabilitated following mineral sands mining were compared with four native reference populations, near Eneabba, Western Australia. In each population, approximately 10 offspring from each of 10 maternal plants were genotyped with 11 highly polymorphic microsatellite markers.

From these data, genetic diversity and mating system parameters were assessed, and found to be equivalent across all populations. Mean allelic diversity and heterozygosity across loci were very high. All populations were completely outcrossing with no bi‐parental inbreeding. Mean correlated paternity, sibship and effective population size estimates for restored and natural populations were not significantly different and reflected uniformly high paternal diversity and wide outcrossing. Equivalent genetic results for restored and natural reference populations indicate successful restitution of bird‐pollinator services for L. multiflora in these post‐mining rehabilitation sites.

Synthesis and applications. Reviewing our results with other published studies to date suggests a resilience of bird‐pollinator services in restored plant communities. These findings provide some reassurance to restoration practitioners working in these global south systems where bird pollination is a feature, at least for similar landscape scenarios. Our study also highlights the global contribution of ecological genetics to the objective assessment of functional species interactions in ecological restoration, an increasingly important goal of land managers and regulators seeking to improve restoration standards.
Reform and reverberation: Australian aged care policy changes and the unintended consequences for allied health
Authors: Gibson Diane , Isbel Stephen 
Published: May 2024

AbstractIntroductionAllied health has a valuable role in providing services to people living in residential aged care. The recent Royal Commission into Aged Care Quality and Safety included several important recommendations relating to the nursing, personal care, and allied health workforce and the care that they provide. The purpose of this paper is to review these recommendations and the Australian Government's policy responses and explore the emerging changes in allied health service provision in residential aged care.MethodsData from the four available Quarterly Financial Reports from the 2022–2023 financial year were extracted and analysed in relation to staff costs and time per person per day across personal care, nursing, and allied health workers. Supplementary data sources including the 2020 Aged Care Workforce Census were accessed to provide contextual data relating to individual allied health professions, including occupational therapy.ResultsThe analysis shows a modest increase in median registered nurse minutes per person per day, and cost per person per day, from the first to second quarter, and again in the third and fourth. By contrast, median time and cost for allied health declined. From 5.6 minutes per person per day in the first quarter, reported allied health minutes fell to 4.6 minutes per person per day in the second quarter, an 18% decrease, and by the fourth quarter was 4.3 minutes per person per day. This is just over half the Australian average of 8 minutes reported to the RCACQS in 2019.ConclusionUnder recent residential aged care reforms, aged care providers have regulatory incentives to concentrate their financial resources on meeting the mandated care hours for registered nurses, enrolled nurses, personal care workers, and assistants in nursing. These same reforms do not mandate minutes of allied health services. Although providers of residential aged care in Australia continue to employ and value allied health, we argue that mandating care minutes for personal and nursing care without mandating the provision of allied health creates a perverse incentive whereby access to allied health services is unintentionally reduced.
On the measurement of corporate governance and its impact on bank profitability and credit risk: The case of Tunisian listed banks
Authors: Jmaii Amal , Zaafouri Noomene , Mehri Hella Guerchi 
Published: May 2024

AbstractThis paper explores the influence of corporate governance on the profitability and credit risk of a sample of listed banks in Tunisia. The methodology involves two main steps. Firstly, principal component analysis is employed to construct a novel governance index, assessing the quality of both internal and external bank governance. This index takes into account the degree of compliance and application of directives and laws mandated by the Tunisian Central Bank regarding banking governance. In the second step, panel data analysis is conducted to scrutinize the impact of internal and external governance mechanisms on the profitability and risk of Tunisian banks. The results reveal that as the governance index increases, the profitability of banks improves in terms of return on assets and stock market performance. Additionally, a higher governance index is correlated with a reduction in credit risks, as indicated by lower instances of non‐performing loans and an increased rate of coverage for classified debts. To enhance the robustness of our results, we calculate a standard governance score based on existing empirical literature. Furthermore, to account for potential endogeneity, we employ the two‐step system generalized method of moments.
Follow the media? News environment and public concern about immigration
Authors: CARVALHO JOÃO , CARMO DUARTE MARIANA , RUEDIN DIDIER 
Published: May 2024

AbstractImmigration is a hot topic in Europe, but research on the media effects on public attention to immigration remains limited. We examine how media coverage affects the degree of importance attached to immigration in seven Western European Union member states. Data come from an extensive analysis of claims in printed newspapers, and the Eurobarometer (2002–2009). The continuous sample of news coverage is aggregated into a biannual panel, and we relate these data to citizens’ perceptions of the most important issues in their country 6 months later (lagged). The public consider immigration more important than other policy‐related issues when there is an increase in the volume of news and more political claims on the topic in the media. The media environment appears to be an exogenous actor that can have agenda‐setting effects on public concern about immigration. Our results highlight limitations of both the ‘policy‐gap’ thesis and thermostatic models of policy making.
The substantive representation of men: Intersectionality, masculinities, and men's interests
Authors: MURRAY RAINBOW 
Published: May 2024

AbstractMen's numerical over‐representation in politics leads to complacency regarding their substantive representation. Yet the men in politics are not descriptively representative of most men and are drawn disproportionately from the most socially privileged groups. Building on theories of representation, intersectionality and masculinities, I argue that men have gendered representational needs that are not adequately met. Power structures among men leave many men marginalized and/or subordinated, and disincentivize the privileged men in power from defending disadvantaged men's interests. Masculinist cultures within politics inhibit discussion of male vulnerability and further undermine the substantive representation of men. I make the case forwhywe should study men's substantive representation and then showhowwe could do so. I propose a groundbreaking research agenda for identifying and measuring men's diverse representational needs, recognizing how these are shaped by gender and its intersection with other identities. Combining insights from objectivist, constructivist and intersectional approaches, I develop a framework for measuring the substantive representation of men that exploreswhorepresents men, whichideologyinforms their claims,which menare included and excluded and whether thegoalsof representation are to transform or uphold the status quo. I offer several illuminations of policies where different men have distinct gendered needs, and offer an extended example using educational outcomes in the United Kingdom to illustrate how privileged men are not effective representatives of disadvantaged men. This article builds the normative case and offers the theoretical tools for addressing an important gap in the study of representation.
KIAA1429 regulates lung adenocarcinoma proliferation and metastasis through the PI3K/AKT pathway by modulating ARHGAP30 expression
Authors: Guo Wei , Wang Tan , Huai Qilin , Guo Lei , Wang Xiaobing , He Jie 
Published: May 2024

AbstractBackgroundAlterations in epigenetic factors are recognized as key contributors to the emergence of human cancer. The active and reversible alteration of N6‐methyladenosine (m6A) RNA is crucial for controlling gene activity and determining cellular destiny. Even with these insights, the triggering of KIAA1429 (also called VIRMA) and its role in lung adenocarcinoma (LUAD) is mostly unclear. As a result, the objective of this study was to elucidate how KIAA1429 contributes to cancer development in LUAD.MethodsThis study utilized multiple methods for investigation, encompassing the in vitro functional examination of KIAA1429 in lung adenocarcinoma cells, transcriptome sequencing, methylation RNA immunoprecipitation sequencing (MeRIP‐seq), as well as RNA stability tests to ascertain the half‐life and stability of the target genes.ResultsThe results indicated that modifying the expression of KIAA1429 regulated the proliferation and metastasis of LUAD. By employing transcriptome sequencing alongside MeRIP‐seq analysis, the research pinpointed genes affected by m6A alterations triggered by KIAA1429. In a more detailed manner, it was discovered that KIAA1429 plays a regulatory role in the expression of ARHGAP30. Suppressing KIAA1429 results in reduced m6A levels in the mRNA of the target gene ARHGAP30, boosting its stability and expression, thus inhibiting tumor proliferation and metastasis.ConclusionThis study revealed the activation mechanism and pivotal function of KIAA1429 in LUAD tumor development, paving the way for molecular‐based interventions for LUAD.
Overcoming the lack of distribution data for range‐restricted habitat specialist frogs
Authors: Barata Izabela M. , Uhlig Vivian M. , Cortês Lara G. , Fath Franciele , Griffiths Richard A. 
Published: May 2024

AbstractWith over 40% of species threatened with extinction, the distributional range of most amphibians is still unknown, generating uncertainty whether species are naturally rare, under‐sampled, or difficult to detect. We implemented a modelling approach that uses bromeliads as surrogates to predict the distribution of habitat specialist frogs that lack distributional data. We aimed to predict and survey potential new sites for the occurrence of a rare and microendemic bromeliad‐dwelling frog from the Atlantic Rainforest of Brazil. We used Maxent to predict suitable areas based on climate and topographic profiles, combined with 21 occurrence records of bromeliads within which our target frog species (Crossodactylodes itambe) is strictly restricted. The bromeliad‐based models identified four areas potentially suitable, and subsequent surveys revealed an entirely new species of a rare bromeliad‐dwelling frog in one of the areas. We demonstrate that using easy‐to‐survey surrogate species that have a strong relationship with species that are hard to detect has enormous potential to reveal crucial information on the potential ranges and distribution of cryptic taxa. Such a surrogate modelling approach could be extended to other habitat specialist species that lack distribution data, such as amphibians restricted to specific refugia and/or reproduction sites. This could improve the targeting of surveys and increase understanding of the patterns of rarity and the drivers of species distribution, especially for areas with high endemicity and range‐restricted frogs.
Genomic analysis of inbreeding level, kinship and breed relationships in Creole cattle from South America
Authors: Marcuzzi O. , Calcaterra F. , Loza Vega A. , Ortega Masagué M. F. , Armstrong E. , Pereira Rico J. A. , Jara E. , Olivera L. H. , Peral García P. , Giovambattista G. 
Published: May 2024

AbstractThe conservation of animal genetic resources refers to measures taken to prevent the loss of genetic diversity in livestock populations, including the protection of breeds from extinction. Creole cattle populations have suffered a drastic reduction in recent decades owing to absorbent crosses or replacement with commercial breeds of European or Indian origin. Genetic characterization can serve as a source of information for conservation strategies to maintain genetic variation. The objective of this work was to evaluate the levels of inbreeding and kinship through the use of genomic information. A total of 903 DNAs from 13 cattle populations from Argentina, Bolivia and Uruguay were genotyped using an SNP panel of 48 K. Also, a dataset of 76 K SNPs from Peruvian Creole was included. Two inbreeding indices (FROH and Fhat2) and kinship relationships were calculated. In addition, effective population size (Ne), linkage disequilibrium, population composition and phylogenetic relationships were estimated. In Creole cattle, FROH ranged from 0.14 to 0.03, and Fhat2 was close to zero. The inferred Ne trends exhibited a decline toward the present for all populations, whereas Creole cattle presented a lower magnitude of Ne than foreign breeds. Cluster analysis clearly differentiated the taurine and Zebu components (K2) and showed that Bolivian Creole cattle presented Zebu gene introgression. Despite the population reduction, Creole populations did not present extreme values of consanguinity and kinship and maintain high levels of genetic diversity. The information obtained in this work may be useful for planning conservation programmes for these valuable local animal genetic resources.
The burden of atopic dermatitis in Australia: Medical care, treatment satisfaction, financial impact, long‐term control and quality of life
Authors: Howie Lynita , Orevillo Kara , Tu Michelle , Schwartz Alan , Funk Melanie , Talent Cheryl , Capozza Korey 
Published: May 2024

AbstractAtopic dermatitis patients and caregivers experience a high physical, mental and financial burden in Australia. We outline how the current care model impacts disease management and patients' quality of life via a survey of 265 Australian patients and caregivers to capture the experience of managing atopic dermatitis (AD) in Australia. Patients report an unsatisfactory quality of life and a high burden of disease with poor long‐term control and low treatment satisfaction. They also reported changing spending and saving patterns to fund medical care. Patient experience improves with more specialised care that incorporates shared decision‐making and patient/caregiver training beyond the clinic visit. These results highlight the need for improved general practitioner (GP) education, expedited access to medical specialists, greater patient involvement in treatment choices and more financial assistance to improve the experience of Australian patients and caregivers.
An enhanced refresher on discounted net present value computations with an additional focus on risk and uncertainty
Authors: Foley Maggie , Wang Shuangjin 
Published: May 2024

AbstractDiscounted present value (DPV) calculations have appeared in textbooks as well as numerous peer‐reviewed journal articles. Such articles address a wide variety of topics/issues, ranging from migration to educational pursuit to investment in new plant and equipment to the NFL draft. Recognizing the remarkably versatile and useful tools that the DPV concepts are to valuation and intelligent decision‐making, some years ago, the Harvard Business Review published a discussion by Gallo of the derivation and uses of DPVs (and NPVs). This note extends and corrects the analysis in Gallo so as to make it more accurate and useful to the reader.