bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study
Authors: Mouzopoulos George , Vasiliadis George , Lasanianos Nikolaos , Nikolaras George , Morakis Emanouil , Kaminaris Michalis 
Published: August 2009

Abstract

Background
Recent studies have indicated that unmanaged pain, both acute and chronic, can affect mental status and might precipitate delirium, especially in elderly patients with hip fractures. The aim of this study was to assess the effectiveness of fascia iliaca compartment block (FICB) for prevention of perioperative delirium in hip surgery patients who were at intermediate or high risk for this complication.

Materials and methods
On admission, all included patients were divided into three groups according to low, intermediate or high risk for perioperative delirium. Eligible patients (those classified as at intermediate or high risk for developing delirium) were sequentially randomly assigned to study treatment (FICB prophylaxis or placebo) according to a computer-generated randomization code. The primary outcome was perioperative delirium. Diagnosis of the syndrome was defined using the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) and Confusion Assessment Method (CAM) criteria. Secondary outcome variables were severity of delirium and delirium duration.

Results
Delirium occurred in 33 (15.94%) out of 207 patients randomized to FICB prophylaxis or the placebo group. Incidence of delirium in the FICB prophylaxis group was 10.78% (11/102), significantly different from the incidence (23.8%, 25/105) in the placebo group [relative risk 0.45, 95% confidence interval (CI) 0.23–0.87]. Nine of 17 patients with high risk for delirium and included in the FICB prophylaxis group developed delirium, whereas 10 of 16 high-risk patients included in the placebo group became delirious (relative risk 0.84, CI 0.47–1.52). Two of 85 patients with intermediate risk for delirium and included in the FICB prophylaxis group developed delirium, whereas 15 of 89 intermediate-risk patients included in the placebo group became delirious (relative risk 0.13, CI 0.03–0.53). Severity of delirium according to the highest value of the DRSR-98 during an episode with delirium in patients in the FICB prophylaxis group was on average 14.34, versus 18.61 in the placebo group (mean difference 4.27, 95% CI 1.8–5.64, P < 0.001). Mean duration of delirium in the FICB prophylaxis group was significantly shorter than in the placebo group (FICB 5.22 days versus placebo 10.97 days, 95% CI 3.87–7.62, P < 0.001).

Conclusion
No significant difference was found among high-risk patients between FICB prophylaxis and placebo groups in terms of delirium incidence. However, FICB prophylaxis significantly prevented delirium occurrence in intermediate-risk patients. Thus FICB prophylaxis could be beneficial, particularly for intermediate-risk patients.
Challenges Faced by Genetics Service Providers’ Practicing in a Culturally and Linguistically Diverse Population: An Australian Experience
Authors: Saleh Mona , Barlow‐Stewart Kristine , Meiser Bettina , Muchamore Ian 
Published: August 2009

AbstractThis paper explores the perceived challenges facing clinical genetics practitioners in multicultural Australia. Focus groups conducted with 53 practitioners explored: 1) participants’ experiences and definitions of cultural diversity; 2) their use of educational resources with clients; 3) their experiences with culturally diverse groups/individuals in practice; 4) their experiences working with interpreters; and 5) the impact culturally specific educational training and/or experiential learning had on their confidence or practice when dealing with culturally diverse clients. Participants viewed culture as extending beyond traditional definitions such as ethnicity, language and religion. Most respondents had experienced positive results working with health care interpreters, although at times, this was a challenge for the family as they preferred privacy and the use of family members as interpreters. Another commonly reported challenge was the limited availability of reliable, culturally appropriate translated resources. Some participants expressed concern that learning theories about specific cultures may lead to stereotypes and that opportunities for formal cultural competence training were limited. Recommendations for practice include the targeting of educational resources to meet the needs of a diverse community and placing cultural competence on the agenda for ongoing training and maintenance of professional standards for clinical genetics practitioners to avoid the current ad hoc approach.
Acute citalopram administration may disrupt contextual information processing in healthy males
Authors: Almeida S. , Glahn D.C. , Argyropoulos S.V. , Frangou S. 
Published: August 2009

AbstractSelective serotonin reuptake inhibitors (SSRI) are the most commonly prescribed antidepressants. It has been suggested however that SSRI administration may affect response inhibition and contextual processing but the available evidence is minimal. Therefore, the purpose of this study was to identify the effect size of acute (within 24 hours) and chronic (28 days) administration of the highly selective SSRI, Citalopram, compared to placebo on response inhibition (measured by the Degraded Symbol Continuous Performance Task [DS-CPT]) and contextual processing (assessed using a Delayed Non-Matching to Sample Task [DNMS]) in healthy males (n = 20) using a randomised double-blind design. We found no effect of Citalopram on participants’ performance on the DS-CPT which suggests either that SSRIs do not affect response inhibition or that this measure is insensitive to any potential disinhibition effects of SSRI. Acute, but not chronic, Citalopram administration was associated with a measurable decrement in the DNMS suggestive of a negative impact of SSRI administration on contextual processing at least during treatment initiation. These findings provide a useful guide for designing future studies in clinical populations.
The immune response to and immunomodulation byHymenolepis diminuta
Authors: McKAY DEREK M. 
Published: August 2009

SUMMARYAnalyses of laboratory-based helminth-rodent model systems have been immensely useful in delineating the workings of the mammalian immune system. Investigations in the 1970s–1980s on the fate of the rat tapeworm,Hymenolepis diminuta, in rats and mice and the systemic and local responses evoked following infection have contributed directly to our knowledge of how permissive and non-permissive hosts respond to the challenge of infection with a helminth parasite. This convenient laboratory model system has, in the authors' opinion, regrettably received considerably less attention in recent years. With the goal of highlighting the utility of this model system, data is presented on: (1) the immune and enteric responses of rats and mice to infection withH. diminuta; (2) the ability of excretory or secretory products derived fromH. diminutato significantly reduce T cell and macrophage activationin vitro; and (3) how assessment ofH. diminuta-rodent models can be used to identify immune effector or regulatory mechanisms that can be translated into novel treatments for inflammatory and autoimmune disorders.
Symptom dimensions of post-myocardial infarction depression, disease severity and cardiac prognosis
Authors: Martens E. J. , Hoen P. W. , Mittelhaeuser M. , de Jonge P. , Denollet J. 
Published: August 2009

BackgroundIndividual symptoms of post-myocardial infarction (MI) depression may be differentially associated with cardiac prognosis, in which somatic/affective symptoms appear to be associated with a worse cardiovascular prognosis than cognitive/affective symptoms. These findings hold important implications for treatment but need to be replicated before conclusions regarding treatment can be drawn. We therefore examined the relationship between depressive symptom dimensions following MI and both disease severity and prospective cardiac prognosis.MethodPatients (n=473) were assessed on demographic and clinical variables and completed the Beck Depression Inventory (BDI) within the first week of hospital admission for acute MI. Depressive symptom dimensions were associated with baseline left ventricular ejection fraction (LVEF) and prospective cardiac death and/or recurrent MI. The average follow-up period was 2.8 years.ResultsFactor analysis revealed two symptom dimensions – somatic/affective and cognitive/affective – in the underlying structure of the BDI, identical to previous results. There were 49 events attributable to cardiac death (n=23) or recurrent MI (n=26). Somatic/affective (p=0.010) but not cognitive/affective (p=0.153) symptoms were associated with LVEF and cardiac death/recurrent MI. When controlling for the effects of previous MI and LVEF, somatic/affective symptoms remained significantly predictive of cardiac death/recurrent MI (hazard ratio 1.31, 95% confidence interval 1.02–1.69, p=0.038). Previous MI was also an independent predictor of cardiac death/recurrent MI.ConclusionsWe confirmed that somatic/affective, rather than cognitive/affective, symptoms of depression are associated with MI severity and cardiovascular prognosis. Interventions to improve cardiovascular prognosis by treating depression should be targeted at somatic aspects of depression.
There's no contest: Human sex differences are sexually selected
Authors: Pound Nicholas , Daly Martin , Wilson Margo 
Published: August 2009

AbstractAn evolutionary psychological perspective drawing on sexual selection theory can better explain sex differences in aggression and violence than can social constructionist theories. Moreover, there is accumulating evidence that, in accordance with predictions derived from sexual selection theory, men modulate their willingness to engage in risky and violent confrontations in response to cues to fitness variance and future prospects.
The multiple adaptive problems solved by human aggression
Authors: Buss David M. 
Published: August 2009

AbstractHuman psychology contains adaptations to deploy aggression as one solution to many distinct adaptive problems. These include expropriating resources, defending against incursions, establishing encroachment-deterring reputations, inflicting costs on rivals, ascending dominance hierarchies, dissuading partner defection, eliminating fitness-draining offspring, and obtaining new mates. Aggression is not a singular strategy. Comprehensive theories must identify the “design features” of multiple adaptations for aggression.
Moderators of sex differences in sexual selection theory
Authors: Pellegrini Anthony D. 
Published: August 2009

AbstractArcher recognizes that sexual selection theory is sensitive to the effects of ecologies on sex differences, yet he does not explain the impact of such variation. For example, to what degree are there sex differences in aggression in polygynous and monogamous societies? I demonstrate how differences in mating perceptions affect the traditional dichotomy that males compete for and females choose mates.
Does sexual selection explain human sex differences in aggression?
Authors: Archer John 
Published: August 2009

AbstractI argue that the magnitude and nature of sex differences in aggression, their development, causation, and variability, can be better explained by sexual selection than by the alternative biosocial version of social role theory. Thus, sex differences in physical aggression increase with the degree of risk, occur early in life, peak in young adulthood, and are likely to be mediated by greater male impulsiveness, and greater female fear of physical danger. Male variability in physical aggression is consistent with an alternative life history perspective, and context-dependent variability with responses to reproductive competition, although some variability follows the internal and external influences of social roles. Other sex differences, in variance in reproductive output, threat displays, size and strength, maturation rates, and mortality and conception rates, all indicate that male aggression is part of a sexually selected adaptive complex. Physical aggression between partners can be explained using different evolutionary principles, arising from the conflicts of interest between males and females entering a reproductive alliance, combined with variability following differences in societal gender roles. In this case, social roles are particularly important since they enable both the relatively equality in physical aggression between partners from Western nations, and the considerable cross-national variability, to be explained.
THE ART OF WAR: IMAGERY OF THE UPPER TEMPLE OF THE JAGUARS, CHICHEN ITZA
Authors: Ringle William M. 
Published: August 2009

AbstractThis paper reexamines the art and architecture of the Upper Temple of the Jaguars, Chichen Itza, in light of new unpublished digital images of Adela Breton's copies of the murals. Following discussion of the construction date of the building and previous interpretations of the murals, examination of costume, setting, and house form suggests that rather than depicting mythic or symbolic episodes, these murals illustrate actual military encounters between Chichen and its enemies. The occasion for their production seems to be the utilization of the Upper Temple of the Jaguars by a specific sector of Chichen Itza's military, perhaps for rites of investiture. This sector is argued to have been associated with the Cloud Serpent, either as the title of its leader or as a patron deity, and the structure itself is perhaps related to later Nahua buildings associated with penitential rites involving warfare and investiture.
GROUND PLATFORM PREPARATION AND THE “BANALIZATION” OF THE PRISMATIC BLADE IN WESTERN MESOAMERICA
Authors: Healan Dan M. 
Published: August 2009

AbstractFor much of their history, prismatic blades were a relatively scarce item whose restricted occurrence suggested they functioned as prestige or luxury items. Some time prior to the Postclassic period, however, they became a widespread, ubiquitous, and mundane commodity in Mesoamerica, as indicated by ethnohistorical accounts as well as archaeological evidence. This occurred around the same time that blademakers began to prepare core platforms by pecking and grinding, a labor intensive process whose advantages are presumed to have played the primary role. The specific causal relationships involved, however, appear to pertain less to factors of increased productivity on the part of individual blademakers than to those of skill, as suggested by comparisons between core/blade technology used in areas close to obsidian sources and those used at sites further removed from the sources.
CRAFT PRODUCTION IN A CENTRAL MEXICAN MARKETPLACE
Authors: Hirth Kenneth 
Published: August 2009

AbstractThe marketplace was an important institution for household provisioning and elite resource conversion in pre-Hispanic Mesoamerica. Despite their importance, marketplaces are difficult to identify because exchange relationships are generally invisible in the archaeological record. This study examines the evidence for marketplaces at the Epiclassic period site of Xochicalco, Morelos, Mexico. It explores the role of craft production in the marketplace as a possible indicator of market activity. Excavations in a suspected market area at Xochicalco uncovered evidence for the production of obsidian prismatic blades on the floor of a public plaza. The results of these explorations are discussed and it is concluded that craft production can be a useful indicator for market activity if production debitage is found in primary contexts in public plazas.
Conflict-Free Colourings of Graphs and Hypergraphs
Authors: PACH JÁNOS , TARDOS GÁBOR 
Published: August 2009

A colouring of the vertices of a hypergraphHis calledconflict-freeif each hyperedgeEofHcontains a vertex of ‘unique’ colour that does not get repeated inE. The smallest number of colours required for such a colouring is called theconflict-free chromatic numberofH, and is denoted by χCF(H). This parameter was first introduced by Even, Lotker, Ron and Smorodinsky (FOCS2002) in ageometricsetting, in connection with frequency assignment problems for cellular networks. Here we analyse this notion for general hypergraphs. It is shown that$\chi_{\rm CF}(H)\leq 1/2+\sqrt{2m+1/4}$, for every hypergraph withmedges, and that this bound is tight. Better bounds of the order ofm1/tlogmare proved under the assumption that the size of every edge ofHis at least 2t− 1, for somet≥ 3. Using Lovász's Local Lemma, the same result holds for hypergraphs in which the size of every edge is at least 2t− 1 and every edge intersects at mostmothers. We give efficient polynomial-time algorithms to obtain such colourings.Our machinery can also be applied to the hypergraphs induced by the neighbourhoods of the vertices of a graph. It turns out that in this case we need far fewer colours. For example, it is shown that the vertices of any graphGwith maximum degree Δ can be coloured with log2+εΔ colours, so that the neighbourhood of every vertex contains a point of ‘unique’ colour. We give an efficient deterministic algorithm to find such a colouring, based on a randomized algorithmic version of the Lovász Local Lemma, suggested by Beck, Molloy and Reed. To achieve this, we need to (1) correct a small error in the Molloy–Reed approach, (2) restate and re-prove their result in adeterministicform.
Diet and cancer in Mediterranean countries: carbohydrates and fats
Authors: Bosetti Cristina , Pelucchi Claudio , La Vecchia Carlo 
Published: August 2009

AbstractObjectiveSeveral aspects of the diet characteristic of the Mediterranean countries are considered favourable not only on cardiovascular disease, but also on cancer risk. We considered some aspects of the Mediterranean diet (including, in particular, the consumption of olive oil and carbohydrates) on cancer risk.Design, Setting and SubjectsData were derived from a series of case-control studies, conducted in Italy since the early 1990s, on over 10 000 cases of thirteen cancer sites and over 17 000 controls.ResultsOlive oil, and other mono- and unsaturated fats, appear to be favourable indicators of breast, ovarian, colorectal, but mostly of upper aero-digestive tract cancers. Whole grain foods are also related to reduced risk of upper aero-digestive tract and various other cancers. In contrast, refined grain intake and, consequently, glycaemic index and glycaemic load were associated to increased risk for several cancer sites. Fish, and hence a diet rich in n-3 polyunsaturated fatty acids, tended to be another favourable diet indicator, while frequent red meat intake was directly related to some common neoplasms. An a priori defined Mediterranean diet score was inversely related to upper digestive and respiratory tract cancers.ConclusionsThese data provide additional evidence that major characteristics of the Mediterranean diet favourably affect cancer risk.
Mediterranean diet, culture and heritage: challenges for a new conception
Authors: Xavier Medina F 
Published: August 2009

AbstractThe aim of the present article is to discuss the role of the Mediterranean diet as a part of Human Culture and Intangible Cultural Heritage. Until the present, Mediterranean diet has been observed as a healthy model of medical behaviour. After its proposal as a Cultural Heritage of the Humanity at UNESCO (United Nations Educational, Scientific and Cultural Organization), Mediterranean diet is actually being observed as a part of Mediterranean culture and starting its concept as an equivalent of Mediterranean Cultural Food System or Mediterranean Culinary System. At the candidacy of Mediterranean diet as a World Cultural Intangible Heritage to be presented at UNESCO in 2008, this new conception is making sense. A new point of view that will be capital in the future discussions about the Mediterranean diet, their challenges and their future perspectives.
The Mediterranean diet: does it have to cost more?
Authors: Drewnowski Adam , Eichelsdoerfer Petra 
Published: August 2009

AbstractObjectiveTo test the viability of the Mediterranean diet as an affordable low-energy-density model for dietary change.DesignFoods characteristic of the Mediterranean diet were identified using previously published criteria. For these foods, energy density (kJ/100 g) and nutrient density in relation to both energy ($/MJ) and nutrient cost were examined.ResultsSome nutrient-rich low-energy-density foods associated with the Mediterranean diet were expensive, however, others that also fit within the Mediterranean dietary pattern were not.ConclusionsThe Mediterranean diet provides a socially acceptable framework for the inclusion of grains, pulses, legumes, nuts, vegetables and both fresh and dried fruit into a nutrient-rich everyday diet. The precise balance between good nutrition, affordability and acceptable social norms is an area that deserves further study. The new Mediterranean diet can be a valuable tool in helping to stem the global obesity epidemic.
Prenatal and childhood Mediterranean diet and the development of asthma and allergies in children
Authors: Chatzi Leda , Kogevinas Manolis 
Published: August 2009

AbstractObjectiveTo discuss current evidence about the relation between prenatal and childhood Mediterranean diet, and the development of asthma and allergies in children.DesignReview of the literature.Setting and resultsFour recent studies conducted in Mediterranean countries (Spain, Greece) and one conducted in Mexico evaluated the association between childhood Mediterranean diet and asthma outcomes in children. All of the studies reported beneficial associations between a high level of adherence to the Mediterranean diet during childhood and symptoms of asthma or allergic rhinitis. Individual foods or food groups contributing to the protective effect of Mediterranean diet included fish, fruits, vegetables, legumes, nuts and cereals, while detrimental components included red meat, margarine and junk food intake.Two studies focused on prenatal Mediterranean diet: the first is a birth cohort in Spain that showed a protective effect of a high adherence to the Mediterranean diet during pregnancy on persistent wheeze, atopic wheeze and atopy at the age of 6·5 years; while the second is a cross-sectional study in Mexico, collecting information more than 6 years after pregnancy, that showed no associations between maternal Mediterranean diet during pregnancy and allergic symptoms in childhood except for current sneezing.ConclusionsFindings from recent studies suggest that a high level of adherence to the Mediterranean diet early in life protects against the development of asthma and atopy in children. Further studies are needed to better understand the mechanisms of this protective effect, to evaluate the most relevant window of exposure, and to address specific components of diet in relation to disease.