bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sándor Ferenczi et les principes d’une éthique du soin dans les pratiques éducatives
Authors: Kupermann Daniel , Dean-Gomes Gustavo 
Published: April 2024

Dans cet article, nous tentons d’expliciter les conséquences de l’application, dans le domaine de l’éducation, des principes d’une éthique du soin tels qu’ils sont développés dans la pensée du psychanalyste Sándor Ferenczi. En effet, on retrouve tout au long de son œuvre des réflexions sur l’éducation. Cependant, nous démontrerons que les principes d’hospitalité, d’empathie et de santé du soigneur, en particulier après le « tournant de 1928 » qu’il a opéré dans le champ de la psychanalyse, sont devenus des repères non seulement pour la pratique clinique, mais également pour aiguiller l’éthique des pratiques éducatives, en évitant le potentiel traumatique présent dans tout acte qui vise à transmettre un savoir.
Narrative interventions: Power sharing and boundary crossing in action
Authors: Jordan Esther Skelley , Stewart Linda S. 
Published: April 2024

This article reflects on the assumptions we make in the design of faculty and graduate student orientations and on the implementation of redesigned orientations that foreground participant narrative. When educational developers purposefully make space for participant stories at their orientations, it is a way not only to share power with graduate students and faculty but also to create a more inclusive environment and sense of belonging. We offer a reflection on educational developer and participant experiences of small narrative interventions in graduate student and faculty orientations at our university in 2021. We find that through foregrounding story sharing we were able to shift from assimilation to acculturation by including, cultivating, and honoring diverse views, creating community, and promoting agency.
Par la fenêtre ou par la porte
Authors: Ackermann Patrick , Bloc Jean-Pierre 
Published: April 2024

De 2019 à 2022, deux procès condamnent la direction de France Télécom-Orange et son P.-D.G. Didier Lombard pour « harcèlement moral institutionnel ». C’est une première en France, une victoire acquise par de longues luttes conduites par l’Intersyndicale après que le P.-D.G. ait organisé le « départ volontaire » de 22 000 salariés en les poussant Par la fenêtre ou par la porte à quitter l’entreprise. Les auteurs du film expliquent ici comment ils ont réalisé ce documentaire, quels objectifs ils ont poursuivis et quels dispositifs cinématographiques ils ont utilisés pour le rendre attractif afin qu’il soit vu par un large public. En creux, ce documentaire interroge les pratiques syndicales et les nouvelles voies à découvrir.
Déployer l’Ésat hors des murs suffit-il à déségréguer les travailleur·euse·s handicapé·e·s ?
Authors: Jaffrès Fanny 
Published: April 2024

La convention des Nations unies relatives aux droits des personnes handicapées (CDPH) de 2006 et ratifiée par la France en 2010 promeut le droit à l’inclusion en milieu ordinaire. En matière d’emploi et de travail, l’article 27 de cette convention défend le droit au travail des personnes handicapées sur la base de l’égalité avec les autres et la mise en œuvre de mesures appropriées pour répondre à leurs besoins spécifiques. Les établissements et services d’accompagnement par le travail (Ésat), comme l’ensemble des institutions spécialisées, se trouvent associés à une forme de ségrégation des personnes handicapées et sont donc remis en question. Pour répondre à l’objectif d’inclusion, les Ésat tendent alors à développer la mise à disposition en milieu ordinaire qui permet à des travailleur·se·s handicapé·es d’exercer une activité professionnelle chez un·e employeur·e ordinaire tout en restant rattaché·es à leur Ésat. Basé sur une recherche doctorale en sociologie conduite entre 2017 et 2021, cet article entend analyser ce dispositif en se demandant dans quelle mesure il permet de répondre à l’objectif d’inclusion auquel il prétend.
Rétrospective et Perspectives de la sociologie du travail en Éthiopie
Authors: Perrin-Joly Constance 
Published: April 2024

Le travail n’est pas un sujet central de la recherche en Éthiopie alors que le pays est traversé par d’importants changements dans le monde professionnel. Cet article s’attache à décrire l’organisation de la recherche éthiopienne pour comprendre le caractère restreint de la production en sociologie du travail. La recherche reste structurée sous l’angle du développement. L’article propose trois perspectives dans lesquels d’importants travaux émergent ou méritent d’être redécouverts : une sociohistoire des premiers établissements industriels, des ouvriers et de leurs mobilisations ; une analyse des parcours et de l’expérience des salarié·es dans les nouvelles industries ; un regard sur le rapport au travail et les segmentations qui le traversent, en particulier sous l’angle du genre.
Long-term outcome of pulmonary involvement in patients with coronavirus disease 2019: The role of high-resolution computed tomography and functional status – A prospective single-center observational study
Authors: Imtiaz Sadia , Batubara Enas M , Abuelgasim Mohammed H , Alabad Mahdi M , Alyousef Lujain Mahmoud , Alqahtani Nayef H , Sabbagh Alaa Y , Alharbi Fawaz A , Ibrahim Ahmed S 
Published: April 2024

BACKGROUND:
Since its first outbreak, coronavirus disease 2019 (COVID-19) has led to a great deal of published literature highlighting the short-term determinants of morbidity and mortality. Recently, several studies have reported radiological and functional sequelae from 3 months to 1 year among hospitalized COVID-19 survivors; however, long-term (more than 1 year) respiratory consequences in this population remain to be evaluated.

OBJECTIVE:
To assess the long-term radiological and pulmonary function outcomes of patients with COVID-19 2 years after resolution of the initial infection.

METHODS:
Hospitalized COVID-19 patients with moderate to severe disease who survived acute illness were included in this prospective and partially retrospective study. Clinical assessment, laboratory tests, high-resolution computed tomography scans, and pulmonary function tests (PFTs) were performed at baseline, followed by radiological and lung function assessments at 6 and 24 months.

RESULTS:
Among 106 enrolled participants (mean age 62 ± 13.5 years; males: 61), 44 (41.5%) and 27 (25.4%) underwent radiological assessment at 6 and 24 months, respectively. Overall, 22.6% (24) of patients had residual radiological abnormalities. Overt fibrosis was observed in 12.2% of patients. Computed tomography disease severity and extent diminished significantly at 6 (13 ± 6, P < 0.001) and 24 months (11 ± 6, P < 0.001) from baseline. PFTs were performed in 65 (61.3%), 22 (20.7%), and 34 (32%) patients at baseline, 6 and 24 months, respectively. Impaired diffusion capacity (median diffusion capacity for carbon monoxide: 60%, interquartile range [IQR]: 51–80), restrictive lung defect (mean total lung capacity: 73.4% ± 18% predicted), and reduced exercise tolerance (median 6-min walk distance: 360 m, IQR: 210–400) were the predominant features at baseline. With the exception of exercise tolerance, a statistically significant improvement was observed in lung function parameters at the extended follow-up (2 years).

CONCLUSIONS:
Hospitalized COVID-19 survivors are at increased risk of developing long-term pulmonary complications, including lung fibrosis. A protocol-based approach to the management of post-COVID-19 patients is mandatory to improve future outcomes.
Continuous positive airway pressure combined with small-tidal-volume ventilation on arterial oxygenation and pulmonary shunt during one-lung ventilation in patients undergoing video-assisted thoracoscopic lobectomy: A randomized, controlled study
Authors: Yang Yudie , Jia Dong , Cheng Lu , Jia Ke , Wang Ji 
Published: April 2024

BACKGROUND:
One-lung ventilation (OLV) is frequently applied during video-assisted thoracoscopic surgery (VATS) airway management to collapse and isolate the nondependent lung (NL). OLV can give rise to hypoxemia as a result of the pulmonary shunting produced. Our study aimed to assess the influence of continuous positive airway pressure (CPAP) combined with small-tidal-volume ventilation on improving arterial oxygenation and decreasing pulmonary shunt rate (QS/QT) without compromising surgical field exposure during OLV.

METHODS:
Forty-eight patients undergoing scheduled VATS lobectomy were enrolled in this research and allocated into three groups at random: C group (conventional ventilation, no NL ventilation intervention was performed), LP group (NL was ventilated with lower CPAP [2 cmH2O] and a 40–60 mL tidal volume [TV]), and HP group (NL was ventilated with higher CPAP [5 cmH2O] and a 60–80 mL TV). Record the blood gas analysis data and calculate the QS/QT at the following time: at the beginning of the OLV (T0), 30 min after OLV (T1), and 60 min after OLV (T2). Surgeons blinded to ventilation techniques were invited to evaluate the surgical fields.

RESULTS:
The demography data of the three groups were consistent with the surgical data. At T1, PaO2 in the HP group was substantially higher compared to the C group (P < 0.05), while there was no significant difference in the LP group (P > 0.05). At T1-T2, PaCO2 in the LP and HP groups was significantly less than that in the C group (P < 0.05). At T1, the QS/QT values of groups C, LP, and HP were 29.54 ± 6.89%, 22.66 ± 2.08%, and 19.64 ± 5.76%, respectively, and the QS/QT values in the LP and HP groups markedly reduced (P < 0.01). The surgical field’s evaluation by the surgeon among the three groups was not notable (P > 0.05).

CONCLUSION:
CPAP combined with small-tidal-volume ventilation effectively improved arterial oxygenation and reduced QS/QT and PaCO2 without compromising surgical field exposure during OLV. Among them, 5 cmH2O CPAP + 60–80 ml TV ventilation had a better effect on improving oxygenation.
Role of impulse oscillometry together with diffusing capacity of the lungs for carbon monoxide and high-resolution computed tomography for the chest in early diagnosis of interstitial lung disease in patients with connective tissue diseases
Authors: Hiekal Abdel HMS , Dayem Aya MMA , Gomaa Ashraf A , Mohamed Mohamed R , Ali Wafaa R , Hendawy Mahmoud M 
Published: April 2024

Abstract

Background
Connective tissue diseases (CTDs) are systemic autoimmune disorders characterized by repeated lung involvement. Interstitial lung disease (ILD) can arise from nearly any CTD, imposing a significant burden on patients and strongly affecting their prognosis. Addressing the gaps in early diagnosis, monitoring, and treatment of these patients requires a comprehensive and multidisciplinary approach for optimal management.

Aim
To find the best modality for early diagnosis of ILD in patients with connective tissue disorders through the use of diffusing capacity of the lungs for carbon monoxide (DLCO), impulse oscillometry (IOS) and high-resolution computed tomography (HRCT) chest.

Patients and methods
This study was cross-sectional, analytical, and observational was conducted on 60 patients who were diagnosed with CTD, during the period from March 2022 to March 2023, who were admitted to Chest and Rheumatology Department or outpatient clinics visitors, to Ain Shams University Hospitals.

Results
The sensitivity of DLCO, HRCT, and IOS in detecting interstitial affection in CTD patients was 90, 81.5, and 72.2%, respectively.
There is high statistical significance between DLCO and both CT chest and IOS in detecting ILD in CTD patients.
There is a highly significant correlation between DLCO with Spirometric parameters (forced vital capacity, forced expiratory volume 1 s) and between DLCO with IOS parameters (actual ×5).

Conclusion
ILD should always be considered in patients with CTD. Diagnosis of CTD-ILD is challenging so early diagnosis of ILD using DLCO, HRCT chest or by using IOS is important as it could affect therapy plans.
Outcome of Acinetobacter baumannii Ventilator Associated Pneumonia in Upper Egypt: does the resistance profile play a role?
Authors: Abdel-Rahim Mona H , Abd–ElNasser Randa A , Hassnein Khaled M , Mahmoud Manal A , Elkhawaga Amal A 
Published: April 2024

Abstract

Background
Ventilator-associated pneumonia (VAP) due to drug resistant Acinetobacter baumannii (A. baumannii) is a challenging nosocomial problem associated with increased morbidity and risk of mortality.

Objective
This study aimed to investigate plasmid mediated quinolone resistance genes (PMQR) as a mechanism of resistance transmission, risk factors and outcome of A. baumannii VAP.

Methods
This prospective cohort study included 100 VAP patients between October 2020 and December 2022. Microbiological confirmation of A. baumannii. was done and PMQR genes were exposed by polymerase chain reaction (PCR). Pneumonia severity index (PSI), risk factors for developing drug resistant A. baumannii VAP, and the outcome were studied.

Results
The proportions of drug sensitive (DS), multidrug (MDR), extensive drug (XDR), and pan drug (PDR) resistant A. baumannii were 14%, 35%, 50%, and 1%, respectively. Majority of PSI classes IV and V showed XDR (66%) and PDR (100%) isolates. Detection of qnrA, qepA and aac(6′)-Ib-cr genes was predominant in PSI classes IV and V. The in-hospital mortality for MDR, XDR, and PDR was 22.7%, 70.5%, and 2.3%, respectively. ICU duration, prior use of carbapenems and use more than 2 antibiotics prior to VAP were risk factors for developing MDR A. baumannii while septic shock, multilobar chest radiography (CXR) infiltration and PSI class were predictors of in-hospital mortality.

Conclusions
VAP caused by MDR, XDR and PDR isolates of A. baumannii which harbors qnrA, qepA and aac(6’)-Ib-cr PMQR genes showed higher PSI classes and increased in-hospital mortality. The number of PMQR genes in A. baumannii isolates, ICU days, use of more than 2 antibiotics, and use of carbapenem prior to VAP, were independent risk factors for the development of drug resistant A. baumannii VAP.
Volume support ventilation versus pressure support ventilation as a weaning mode of mechanically ventilated patients with chronic obstructive pulmonary disease
Authors: Ghanem Maha K , Makhlouf Hoda A , Taghyan Alaa M , Hassan Ali A 
Published: April 2024

Abstract

Background
A dual controlled ventilatory mode called volume support ventilation (VSV) is anew mode, which is intended to speed up weaning and encourage spontaneous breathing. The purpose of the study was to compare the effectiveness of pressure support ventilation (PSV) and VSV in weaning patients with chronic obstructive pulmonary disease (COPD) who are mechanically ventilated.

Patients and methods
Fifty COPD patients admitted to the respiratory ICU were enrolled. Patients were assigned randomly to either PSV or VSV as a weaning mode. Patients were checked on at intervals of 30, 60 min, and 24 h. Results of weaning and hospital outcomes were recorded.

Results
Compared with PSV, VSV showed significant shorter weaning duration (12.76 ± 8.02 vs. 18.56 ± 5.97 h, P=0.04). Moreover, there was a higher successful extubation rate of 80% for VSV group compared with 76% for PSV, with the same complications and death rate between the two groups.

Conclusion
When compared to PSV mode, VSV mode was a safer, more dependable strategy that may be used responsibly for weaning trials in COPD patients. It also has the potential to shorten ICU stays and weaning times.
MMP-7, RANKL mRNA expression in the gingival tissue correlates with periodontitis: An in vivo study
Authors: Khuda Fazle , Baharin Badiah , Anuar Nur N. M. , Jayusman Putri A. , Nasruddin Shaqinah N. 
Published: April 2024

Introduction
MMP-7 supports the immune response and can have both beneficial and destructive effects. As part of the innate host defense, MMP-7 is connected to the mucosal antimicrobial defense. Even though research on other Matrix metalloproteinase (MMPs) is well-established, understanding MMP-7 expression is required to establish an improved diagnostic strategy. This research investigates the mRNA expression of MMP-7 and RANKL by RT-qPCR assay.

Methods and material
Twelve male Sprague Dawley rats were allocated into three groups, no treatment, experimental (7 and 14 days). Periodontitis is induced by sterile wire insertion (0.2 mm) and Enterococcus faecalis inoculation within the gingival sulcus situated between the maxillary right 1st and 2nd molar tooth regions. Following euthanasia, tissue samples from the maxillary gingiva and maxillary jaw were extracted for quantitative real-time PCR assay and histopathological assessment.

Results
Results showed that at 7 days, there was significant upregulation of MMP-7, which was downregulated in 14 days, as well as migration of the junctional epithelium, attachment loss, inflammatory cells, and fibroblasts, as observed by histological analysis.

Conclusions
Thus, the study suggests that MMP-7 is associated with the progression of periodontitis.
Hepatoprotective effect of jojoba oil against lead-induced toxicity in rats
Authors: El-Saeed Rasha A. , El-Khawaga Omali Y. 
Published: April 2024

Background
Previous investigations showed that jojoba oil exhibited a protective effect against hepatotoxicity caused by different toxicants, however, to the best of our knowledge, no prior research has been done to determine the effectiveness of jojoba oil in protecting against lead toxicity.

Objective
This study assessed the hepatoprotective properties of jojoba oil against lead toxicity in rats.

Materials and methods
The study included four groups, each consisting of six Sprague Dawley male rats, and orally administered jojoba oil (JO group), lead acetate (LA group), and lead acetate plus jojoba oil (protective group)

Results and conclusion
The results showed that lead acetate-induced hepatotoxic effects were revealed by increased serum alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase activities with hepatic histomorphological changes. There was a significant increase in serum total cholesterol, triglycerides, and low-density lipoprotein-cholesterol, while levels of high-density lipoprotein-cholesterol significantly declined compared to normal rats. Additionally, lead acetate triggered oxidative damage of hepatocytes, evidenced by a significant increase of malondialdehyde levels and a decrease of reduced glutathione levels and activities of superoxide dismutase and glutathione S-transferase. Administration of lead was associated with a change in the distribution of cells over different cell cycle phases, characterized by a marked increase in the sub G1 cell population and a significant decrease in the G0/G1 cell population. Supplementation of jojoba oil with lead acetate relieved the toxic impacts of lead acetate with an enhancement of the liver enzyme activities, antioxidant status, lipid profile parameters, and histopathological alterations. In conclusion, jojoba oil might be an effective natural product that offers a promising preventive action towards lead-induced liver damage in rats.
Autoantibodies in epileptic patients indicate the autoimmune epilepsy
Authors: Naser Hajer N. , Ali Naael H. , Derraj Maysoon K. 
Published: April 2024

Background
Epilepsy is a multifaceted neurological condition marked by recurring seizures. Delving into the functions of VGKC (voltage-gated potassium channels), AMPA GluR3 (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit 3), GAD65 (glutamate decarboxylase 65), and LGI1 (leucine-rich glioma-inactivated 1) in epilepsy yields significant perspectives into the fundamental immunological mechanisms of this disorder.

Objective
The study target was to assess the clinical significance of neural autoantibody biomarkers in patients with epilepsy and determine the types of autoimmune epilepsy.

Materials and methods
A case–control study that comprised 50 epilepsy patients (33 males and 17 females) and 40 controls (21 males and 19 females), the patients and controls attending Basrah Teaching Hospital between November 2022 and March 2023, Basrah City, Southern Iraq. The control age ranged from 2 to 62 years and patients’ age 2–68 years were considered the control group in this study. The VGKC, AMPA GluR3, GAD65, and LGI1 were measured using the sandwich ELISA technique.

Results and conclusion
There is no statistically significant difference between the patients and control group for VGKC, GAD65, and LGI1 (P=0.460, P=0.061, and P=0.440, respectively), while there is a statistically significant difference between the patients and the control group for AMPA GluR3 (P=0.012). GAD65 appeared an elevation in epilepsy patients but was not statistically significant. This upregulation may contribute to the hyperexcitability observed in the epileptic brain and potentially play a role in seizure generation and propagation.
Silica nanoparticles improve growth, chemical bioactive, and antioxidant enzyme activity of Dianthus caryophyllus L., plant
Authors: El-Sayed Iman M. , Soliman Dina M. 
Published: April 2024

Background
Nanotechnology has provided innovative use of various materials with unique properties. These substances may react positively in plants, and the induction of bioactive compounds and antioxidant activity is particularly remarkable. Ornamental plant production is a positive economic activity of great interest, especially Carnation (Dianthus caryophyllus L.). This plant is more attractive for its various colors, but the flower quality and its longevity can diminish very fast. Thus, examining methods capable of improving flower quality and vase life is crucial. Additionally, carnation can be used to treat coronary and nervous disorders. Carnation contains compounds that calm the nervous system and minimize swelling and inflammation.

Objective
This research aimed to evaluate the effect of silica nanoparticles (SiO2 NPs) on the growth, bioactive chemical analysis, enzyme activity, and antioxidant accumulation.

Material and methods
The different rates of SiO2 NPs (0, 150, and 300 ppm) were used in two ways: foliar spray and soil drench; it was applied 3 times. The first application was after 3 weeks of transplanting and repeated with 21-day intervals.

Results and conclusion
The results showed that foliar application of SiO2 NPs increased all morphological and flowering traits compared with drench and the control, higher levels of photosynthetic pigments and anthocyanin, greater total phenols, total sugars, and total free amino acids were obtained from plants treated with foliar spray 300 ppm followed than 150 ppm. In addition, the greatest levels of enzyme activity were recorded with plants treated with foliar spray of SiO2 NPs at a rate of 300 ppm, as well as improved anatomical structure of the stem and stomata properties compared with the drench method and control. Similarly, SiO2 NPs application method is more critical than their concentration. Therefore, it is recommended that foliar spraying of SiO2 NPs at 300 ppm can enhance plant growth, flowering, bioactive compounds, enzyme activity, and anatomical structure of the stem of carnation plants while adding SiO2 NPs drench at a rate of 150 ppm had rather acceptable findings.