bluuebunny/crossref_metadata_2025_split huggingface dataset:
Water quality evaluation based on water quality index and multiple linear regression: A research on Hanyuan Lake in southern Sichuan Province, China
Authors: Su Kai , Peng Zhongshan , Zhu Dan , Liu Ruiqian , Wang Qin , Cao Rong , He Jun 
Published: May 2024

AbstractThis study aims to understand the changes in the water quality of Hanyuan Lake and to show these changes over time. In this study, monthly sampling was conducted at three sampling sites in Hanyuan Lake, and water samples were measured for water quality indicators in the laboratory according to the methods specified in the Environmental Quality Standards for Surface Water (GB3838‐2002). Based on the monitoring data from January to December 2019, the WQI comprehensive evaluation method was used to conduct multiple linear stepwise regression analysis, extract key indicators, and establish the WQImin model. The results show that according to the WQI comprehensive evaluation method, the WQI values of Hanyuan Lake are all above 90, and the grade is excellent. The overall water quality of Hanyuan Lake is excellent, and most of the water quality indexes reach the Class I standard in the Environmental Quality Standards for Surface Water (GB3838‐2002). WQImin1 (R2 = 0.86, p < 0.001, PE = 4.28) as the best WQImin model. In this study, a model with fewer parameters was established by multiple linear regression method, which is conducive to better monitoring of water quality at monitoring stations while saving costs.Practitioner Points
According to the WQI comprehensive evaluation method, the WQI values of Hanyuan Lake are all above 90, the rating is excellent.
From January 2019 to September 2020, the monthly change trend of each section is roughly the same, showing a trend of first decreasing, then rising, then decreasing, and finally rising and flattening.
The WQImin model was developed to completely describe the change in the water body.
Replicating Current Procedural Terminology code assignment of rhinology operative notes using machine learning
Authors: Cheng Christopher P. , Sicard Ryan , Vujovic Dragan , Vasan Vikram , Choi Chris , Lerner David K. , Iloreta Alfred‐Marc 
Published: May 2024

AbstractObjectivesDocumentation and billing are important and time‐consuming parts of an otolaryngologist's work. Given advancements in machine learning (ML), we evaluated the ability of ML algorithms to use operative notes to classify rhinology procedures by Current Procedural Terminology (CPT®) code. We aimed to assess the potential for ML to replicate rhinologists' completion of their administrative tasks.Study DesignRetrospective cohort study.SettingUrban tertiary hospital.MethodsA total of 594 operative notes from rhinological procedures across six CPT codes performed from 3/2017 to 4/2022 were collected from 22 otolaryngologists. Text was preprocessed and then vectorized using CountVectorizer (CV), term frequency‐inverse document frequency, and Word2Vec. The Decision Tree, Support Vector Machine, Logistic Regression and Naïve Bayes (NB) algorithms were used to train and test models on operative notes. Model‐classified CPT codes were compared to codes assigned by operating surgeons. Model performance was evaluated by area under the receiver operating characteristic curve (ROC‐AUC), precision, recall, and F1‐score.ResultsPerformance varied across vectorizers and ML algorithms. Across all performance metrics, CV and NB was most overall the best combination of vectorizer and ML algorithm across CPT codes and produced the single best AUC, 0.984.ConclusionsIn otolaryngology applications, the performance of basic ML algorithms varies depending on the context in which they are used. All algorithms demonstrated their ability to classify CPT codes well as well as the potential for using ML to replicate rhinologists' completion of their administrative tasks.
Technical details of robotic pancreatojejunostomy using a modified Blumgart anastomosis: Thread manipulation using gauze and an assisted port
Authors: Uchida Yuichiro , Takahara Takeshi , Mizumoto Takuya , Nishimura Akihiro , Mii Satoshi , Iwama Hideaki , Kojima Masayuki , Kato Yutaro , Uyama Ichiro , Suda Koichi 
Published: May 2024

AbstractBackgroundsPancreatojejunostomy is a technically demanding procedure during robotic pancreaticoduodenectomy (RPD). Modified Blumgart anastomosis (mBA) is a common method for the pancreatojejunostomy; however, the technical details for robotic mBA are not well established. During RPD, we performed a mBA for the pancreatojejunostomy using thread manipulation with gauze and an additional assist port.MethodsPatients who underwent robotic pancreatoduodenectomy at Fujita Health University from November 2009 to May 2023 were retrospectively investigated, and technical details for the robotic‐modified Blumgart anastomosis were demonstrated.ResultsAmong 78 patients who underwent RPD during the study period, 33 underwent robotic mBA. Postoperative pancreatic fistula (POPF) occurred in six patients (18%). None of the patients suffered POPF Grade C according to the international study group of pancreatic surgery definition. The anastomotic time for mBA was 80 min (54–125 min).ConclusionRobotic mBA resulted in reasonable outcomes. We propose that mBA could be used as one of the standard methods for robotic pancreatojejunosotomy.
Higher-derivative corrections to flavoured BPS black hole thermodynamics and holography
Authors: Cassani Davide , Ruipérez Alejandro , Turetta Enrico 
Published: May 2024

Abstract
A Cardy-like regime of the four-dimensional superconformal index has been shown to be governed by ’t Hooft anomalies and to single out a large-N saddle carrying the Bekenstein-Hawking entropy of dual supersymmetric black holes in AdS5. For the universal index where no flavour fugacities are turned on, this correspondence has been improved by matching the first subleading corrections to the saddle-point action with the four-derivative corrections to the black hole action in minimal gauged supergravity, as well as the respective corrected entropies. Here, we extend this match by including flavour symmetries. We consider five-dimensional gauged supergravity with vector multiplet and four-derivative couplings, and provide an effective theory reproducing the ’t Hooft anomalies of the R- and flavour symmetries of generic holographic superconformal field theories at next-to-leading order in the large-N expansion. Then we focus on a specific model dual to ℂ3/ℤν quiver gauge theories, where the ’t Hooft anomaly coefficients receive simple but sufficiently generic corrections. In this model, we evaluate the four-derivative corrections to the on-shell action of the supersymmetric multi-charge black hole, showing agreement with the flavoured Cardy-like formula from the index. We give a prediction for the corrected entropy of the supersymmetric black hole and discuss the general validity of our results. Taking the limit of infinite AdS5 radius, we also obtain four-derivative corrections to the action and entropy of supersymmetric asymptotically flat black holes.
A neutrino floor for the Migdal effect
Authors: Herrera Gonzalo 
Published: May 2024

Abstract
Neutrino-nucleus scatterings in the detector could induce electron ionization signatures due to the Migdal effect. We derive prospects for a future detection of the Migdal effect via coherent elastic solar neutrino-nucleus scatterings in liquid xenon detectors, and discuss the irreducible background that it constitutes for the Migdal effect caused by light dark matter-nucleus scatterings. Furthermore, we explore the ionization signal induced by some neutrino electromagnetic and non-standard interactions on nuclei. In certain scenarios, we find a distinct peak on the ionization spectrum of xenon around 0.1 keV, in clear contrast to the Standard Model expectation.
A bone remodeling approach encoding the effect of damage and a diffusive bio-mechanical stimulus
Authors: Addessi Daniela , D’Annibale Francesco , Placidi Luca , Giorgio Ivan 
Published: May 2024

AbstractThe paper focuses on the effect of damage on the bone remodeling process. This is a crucial, although complex, aspect. A one-dimensional continuous deformable body is employed to model living bone tissue. The model incorporates the bone functional adaptation through an evolution law for an effective elastic modulus driven by mechanical feedback via a mechano-transduction diffusive signal. This type of information transduction, i.e., diffusion, is essential for the model to take into account remodeling in the case of minor injury or pathology-affected regions where there is no signal production. In addition, the model is able to also take into account potential tissue damage that may evolve over time according to a suitable evolution law. To illustrate the capability of the model to describe the mentioned complex coupled phenomena, numerical tests have been performed encompassing high external loads causing the onset of damage and cyclic loading for healing. The numerical simulations carried out via finite-element analyses yield insights into the mechanisms of bone remodeling, with the final goal of aiding clinical decisions and implant designs for bone health and repair. Overall, a key aspect of the paper is to highlight the feasibility of modeling the evolution in bone elasticity arising from the combined effect of damage and remodeling.
Existence and nonexistence of solutions for the mean curvature equation with weights
Authors: Filippucci Roberta , Zheng Yadong 
Published: May 2024

AbstractIn this paper we study existence and nonexistence of positive radial solutions of a Dirichlet problem for the prescribed mean curvature operator with weights in a ball with a suitable radius. Because of the presence of different weights, possibly singular or degenerate, the problem under consideration appears rather delicate, it requires an accurate qualitative analysis of the solutions, as well as the use of Liouville type results based on an appropriate Pohozaev type identity. In addition, sufficient conditions for global solutions to be oscillatory are given.
Simultaneous quantification of terpenes and cannabinoids by reversed-phase LC-APCI-MS/MS in Cannabis sativa L. samples combined with a subsequent chemometric analysis
Authors: Raeber Justine , Poetzsch Michael , Schmidli Anina , Favrod Sina , Steuer Christian 
Published: May 2024

AbstractCannabis sativa L. has been the most discussed medicinal plant in recent years. In particular, the dynamic shift from a formerly illicit and tightly controlled substance to a plant recognized for both medicinal and recreational purposes has brought C. sativa into the global spotlight. Due to the ongoing international legalization processes, fast and convenient analytical methods for the quality control of C. sativa flowers for medicinal and recreational purposes are of tremendous interest. In this study, we report the development and validation of a liquid chromatography-tandem mass spectrometry (LC–MS/MS)-based method applying atmospheric pressure chemical ionization (APCI) to fully quantify 16 terpenes and 7 cannabinoids including their acidic forms by a single chromatographic method. The method presented here is unique and simple, as it eliminates the need for derivatization reactions and includes the unconventional analysis of volatile compounds by liquid chromatography. Samples were prepared by a simple and fast ethanolic extraction. Separation was accomplished within 25 min on a reversed-phase C18 column. Method validation was conducted according to international guidelines regarding selectivity, accuracy, precision, robustness, and linearity. Detection was done in multiple reaction monitoring, which allowed the simultaneous quantification of co-eluting analytes applying two selective mass transitions. In addition, due to reproducible in-source decarboxylation, the acidic forms of cannabinoids were reliably quantified using mass transitions of the neutral forms. The accuracy given as the bias was below 15% for all analytes. Matrix effects for cannabinoids were studied by spiking Humulus lupulus extracts with the analytes at varying concentrations. APCI did not show susceptibility toward ion suppression or enhancement. In addition, the recovery effect after spiking was between 80 and 120% for terpenes. Further, 55 authentic C. sativa extracts were fully quantified, and the obtained results for the terpene profiles were compared to state-of-the-art gas chromatography coupled to flame ionization detection. Comparable results were achieved, emphasizing the method’s applicability for cannabinoids and terpenes. Further, acquired metabolite patterns for C. sativa samples were studied, identifying a relationship between cannabinoid and terpene patterns, as well as the abundance of myrcene in CBD-dominant C. sativa strains.
Graphical Abstract
The Causal Relationship between PCSK9 Inhibitors and Osteoporosis Based on Drug-Targeted Mendelian Combined Mediation Analysis
Authors: Zhang Naidan , Ji Chaixia , Liu Li , Ye Ermei , Yuan Chengliang 
Published: May 2024

AbstractPCSK9 inhibitors have been shown to lower serum low density lipoprotein cholesterol (LDL-C) levels and are considered integral in the treatment of cardiovascular diseases. However, the potential association between PCSK9 inhibitors and osteoporosis is unclear now. In this study, drug-targeted mendelian randomization (MR) was utilized in conjunction with mediation analysis including bone mineral density (BMD), total 25-hydroxyvitamin D (T25(OH)D) levels and calcium supplementation to investigate the causal relationship between PCSK9 inhibitors and osteoporosis. The LDL-C level was chosen as the exposure variable in a sample size of 173,082 individuals. We conducted a MR analysis on the relationship between PCSK9 inhibitors and osteoporosis, elucidating the mediators involved. Utilizing the inverse variance weighted (IVW) method, we found the risk of osteoporosis was reduced by 0.6% in those who used PCSK9 inhibitors compared with non-users (OR: 0.994, 95%CI: 0.991–0.998, P < 0.001). In people aged 30–45 years, the risk of low BMD was 1.176 times higher among PCSK9 inhibitor users compared to non-users (OR: 1.176, 95%CI: 1.017–1.336, P = 0.045). Conversely, people aged 45–60 years who used PCSK9 inhibitors had a 14.9% lower risk of low BMD compared to non-users (OR: 0.851, 95%CI: 0.732–0.968, P = 0.007). Mediation analysis revealed that 43.33% of the impact of PCSK9 inhibitors on osteoporosis was mediated through BMD levels, with the remaining 56.67% being a direct effect. Effects of PCSK9 inhibitors on BMD levels varied in different ages. In addition, the risk of high serum T25(OH)D levels were 1.091 times among PCSK9 inhibitor users compared to non-users (OR: 1.091, 95%CI: 1.065–1.112, P < 0.001), providing valuable insights for clinicians.
Dissecting the role of soybean rhizosphere-enriched bacterial taxa in modulating nitrogen-cycling functions
Authors: Wang Tianshu , Gao Miao , Shao Weiwei , Wang Li , Yang Chunyan , Wang Xing , Yao Shuihong , Zhang Bin 
Published: May 2024

Abstract
Crop roots selectively recruit certain microbial taxa that are essential for supporting their growth. Within the recruited microbes, some taxa are consistently enriched in the rhizosphere across various locations and crop genotypes, while others are unique to specific planting sites or genotypes. Whether these differentially enriched taxa are different in community composition and how they interact with nutrient cycling need further investigation. Here, we sampled bulk soil and the rhizosphere soil of five soybean varieties grown in Shijiazhuang and Xuzhou, categorized the rhizosphere-enriched microbes into shared, site-specific, and variety-specific taxa, and analyzed their correlation with the diazotrophic communities and microbial genes involved in nitrogen (N) cycling. The shared taxa were dominated by Actinobacteria and Thaumarchaeota, the site-specific taxa were dominated by Actinobacteria in Shijiazhuang and by Nitrospirae in Xuzhou, while the variety-specific taxa were more evenly distributed in several phyla and contained many rare operational taxonomic units (OTUs). The rhizosphere-enriched taxa correlated with most diazotroph orders negatively but with eight orders including Rhizobiales positively. Each group within the shared, site-specific, and variety-specific taxa negatively correlated with bacterial amoA and narG in Shijiazhuang and positively correlated with archaeal amoA in Xuzhou. These results revealed that the shared, site-specific, and variety-specific taxa are distinct in community compositions but similar in associations with rhizosphere N-cycling functions. They exhibited potential in regulating the soybean roots’ selection for high-efficiency diazotrophs and the ammonia-oxidizing and denitrification processes. This study provides new insights into soybean rhizosphere-enriched microbes and their association with N cycling.

Key points
• Soybean rhizosphere affected diazotroph community and enriched nifH, amoA, and nosZ.
• Shared and site- and variety-specific taxa were dominated by different phyla.
• Rhizosphere-enriched taxa were similarly associated with N-cycle functions.
Peroperative Cooling in Rhinoplasty: Does it Differ?
Authors: Turhal Goksel , Berber Veysel , Isler Efe , Gode Sercan 
Published: May 2024

Abstract
The main causes of ecchymosis and edema are osteotomy (bone manipulation), dissection of subcutaneous tissue, and skin manipulation in the rhinoplasty procedure. Eyelid edema following surgery can potentially affect visual acuity, particularly during the initial twenty-four hours after the procedure. These may also delay the patient’s return to their normal social life therefore hampering their quality of life. Various surgical and medical methods have been reported to address these issues. This study aimed to compare the effects of using cold saline (0–4 °C) versus room temperature saline (20–25 °C) irrigation throughout the surgery on postoperative edema, ecchymosis, and pain. Fifty patients who underwent open-approach primary rhinoplasty between August 2022 and August 2023 at a tertiary academic center were included. Fifty patients were randomly divided into two groups depending on using cold saline (0–4 °C) (group 1) or room temperature saline (20–25 °C) (group 2) during surgical site irrigation. Patients were assessed for pain, edema, and bruising using a VAS (Visual Analog Scale) on the second and seventh postoperative days. Visual analog score (VAS) was used for subjective outcome analyses. Each patient scored the severity of their periorbital ecchymosis on day two and seven. Periorbital ecchymosis was also evaluated on the second and seventh postoperative days using the SPREE (Surgeon Periorbital Rating of Edema and Ecchymosis) scale. On the second postoperative day, the VAS pain score in group 1, where cold water was used, was found to be statistically and significantly different from the control group (group 2) (p < 0.05). However, there was no statistically significant difference between both groups when comparing the VAS pain scores on the seventh postoperative day. Regarding the VAS ecchymosis score on the seventh postoperative day, there was a statistically significant difference favoring group 1 (p < 0.05). The SPREE scale data also indicated that group 1 had significantly lower scores on the seventh day (p < 0.05). While the SPREE scores on the second day were lower in group 1 than in group 2, this difference did not reach statistical significance (p = 0.061). The findings from our study show that cold saline irrigation may contribute to intraoperative hemostasis by inducing local vasoconstriction. We observed that intraoperative bleeding decreased with the use of cold saline. This approach has the potential to improve patient satisfaction and overall quality of life by reducing postoperative ecchymosis without significantly increasing the cost of the surgical procedure.

Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Comparison of Resorption in Autogenous Dorsal Onlay Cartilage Grafts: An Experimental Study
Authors: Öner Fatih , Kozan Günay 
Published: May 2024

Abstract
Objectives
The present study was designed to compare the graft resorption characteristics of autogenous cartilage from the septum, auricle, and costal in the superficial muscular aponeurotic system of the nasal dorsum of the rabbit model.

Methods
Equal-sized perichondrium-free septal, auricular, and costal cartilage grafts were collected from fifteen New Zealand white rabbits. Cartilage grafts were taken at the scale of two grafts from each animal’s ear, two from its costal part, and one from its septum. Costal cartilage grafts that were shaped with a micro-motor device and monopolar electrocautery, elastic cartilage grafts that were shaped with a micro-motor device and monopolar electrocautery, and septal cartilage grafts that were shaped with a scalpel were all implanted into the dorsum of rabbit’s noses to create five groups. All autogenous cartilage tissues were removed 3 months later. Cartilages were evaluated for histological features, graft mass, and chondrocyte density resorption.

Results
The elastic cartilage group, where electrocautery was used to shape the cartilage, had a higher resorption score than the other groups. The costal cartilage graft shaped with a micro-motor was also observed to have the best cartilage regeneration score.

Conclusion
We observed that the resorption of costal cartilage was lower than that of ear and septum cartilage. It was determined that micro-motor application for the shaping process caused less resorption and stimulated more regeneration than cautery application.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Soil chemical properties associated with penguin carrion in Barton Peninsula, King George Island, Antarctica
Authors: Zaini Nur Adilla , Ismail Siti Sofo , Low Van Lun , Mahmud Mohd Hafizi , Houssaini Jamal , Lee Won Young , Heo Chong Chin 
Published: May 2024

AbstractCarrion decomposition has a significant impact on soil chemical profiles. However, soil nutrient research associated with animal carcasses in Antarctica has been relatively scarce, and the effect of penguin carrion decomposition on soil chemical composition is largely unknown. We aimed to determine Antarctica’s soil chemistry profiles associated with penguin carrion. Soil samples were collected from a penguin rookery near King Sejong Station, Barton Peninsula, King George Island, Antarctica. Dry combustion methods were used to identify soil nitrogen and sulfur, while ammonia, nitrate, and phosphate were determined colorimetrically using a spectrophotometer. In addition, total carbon, pH, electrical conductivity, soil moisture, and soil porosity were also determined. Overall, soil chemical properties were not significantly different between the stages of decomposition and the sampling locations. These findings suggest that nutrients from penguin carrion disperse and leach in limited quantities into the soil, probably due to the active scavenging activities by vertebrate scavengers and the slower decomposition rate resulting from cold temperatures in the Antarctic region.