bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations of accelerometer-measured physical activity and sedentary time with renal function and chronic kidney disease: a national population-based study
Authors: Suo Xiangying , Liu Yanhua , Amoah Adwoa Nyantakyiwaa , Bo Yacong , Lyu Quanjun 
Published: June 2024

IntroductionThere is limited information about the relationship between physical activity (PA) and sedentary behaviors in chronic kidney disease (CKD). Therefore, this study aims to explore the associations of accelerometer-measured PA and sedentary behaviors with CKD.MethodsA cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey in the 2003–2004 and 2005–2006 survey cycles. A uniaxial accelerometer measured physical activity (PA) and sedentary time (ST). The associations of PA and ST with estimated glomerular filtration rate (eGFR) and odds of CKD adopted the generalized linear regression, multivariable logistic regression, and isotemporal substitution models.ResultsA total of 5,990 adults with 605 CKD patients were included in this study. Compared with the individuals in the first quartile group, participants in the fourth quartile of low-intensity physical activity (LIPA), moderate to vigorous physical activity (MVPA), and ST were associated with 52% (35%, 65%) and 42% (14%, 62%) lower odds of CKD and 64% (17%, 131%) higher odds of CKD, respectively. Substituting 30 min/day of ST with equivalent LIPA/MVPA contributed to risk reduction in CKD.DiscussionThe findings suggest that increased LIPA and MVPA and reduced ST were associated with a lower risk of CKD and that replacing ST with LIPA may decrease the risk of CKD.
Natural history and surgical outcomes of Rathke’s cleft cysts: a Spanish multicenter study
Authors: Menéndez-Torre Edelmiro Luis , Gutiérrez-Hurtado Alba , Ollero María Dolores , Irigaray Ana , Martín Patricia , Parra Paola , González-Molero Inmaculada , Araujo-Castro Marta , Idrobo Cindy , Moure María Dolores , Molina Ana Rosa , Biagetti Betina , Iglesias Pedro , Paja Miguel , Villar-Taibo Rocío , Pena Alberto , Vicente Almudena , Guerrero-Pérez Fernando , Cordido Fernando , Aulinas Anna , Mateu Manel , Soto Alfonso 
Published: June 2024

Rathke’s cleft cysts (RCC) are a common type of lesion found in the sellar or suprasellar area. They are usually monitored clinically, but in some cases, surgery may be required. However, their natural progression is not yet well understood, and the outcomes of surgery are uncertain. The objective of this study is to evaluate the natural history of Rathke’s cleft cysts in patients who are clinically monitored without treatment, and to determine the outcomes of surgery and the incidence of recurrences over time.Design and patientsNational multicentric study of patients diagnosed of Rathke’s cleft cyst (RCC- Spain) from 2000 onwards and followed in 15 tertiary centers of Spain. A total of 177 patients diagnosed of RCC followed for 67.3 months (6–215) and 88 patients who underwent surgery, (81 patients underwent immediate surgery after diagnosis and 7 later for subsequent growth) followed for 68.8 months (3–235).ResultsThe cyst size remained stable or decreased in 73.5% (133) of the patients. Only 44 patients (24.3%) experienced a cyst increase and 9 of them (5.1%) experienced an increase greater than 3 mm. In most of the patients who underwent surgery headaches and visual alterations improved, recurrence was observed in 8 (9.1%) after a median time of 96 months, and no predictors of recurrence were discovered.ConclusionsRathke’s cleft cysts without initial compressive symptoms have a low probability of growth, so conservative management is recommended. Patients who undergo transsphenoidal surgery experience rapid clinical improvement, and recurrences are infrequent. However, they can occur after a long period of time, although no predictors of recurrence have been identified.
Rhizosphere Mortierella strain of alfalfa exerted weed growth inhibition by inducing expression of plant hormone-related genes
Authors: Du Taotao , Qu Xudong , Wang Yibo , Li Meixuan , Qie Xihu , Jin Jing , Gao Yuxuan , Wang Zengyu , Lin Kejian , Yang Chao , Sun Juan 
Published: June 2024

IntroductionWeeds are significant factors that detrimentally affect crop health and hinder optimal herbage yield. Rhizosphere microorganisms play crucial roles in plant growth, development, and nutrient uptake. Therefore, research focusing on weed control through the lens of microorganisms has emerged as a prominent area of study. The oil-producing fungus Mortierella, which is known for its numerous agricultural benefits, has garnered significant attention in recent years.MethodsIn this study, we conducted inoculation experiments in a controlled artificial culture climate chamber to investigate the effects of differential hormones and differentially expressed genes in the stems and leaves of Digitaria sanguinalis using Liquid Chromatography Tandem Mass Spectrometry and RNA-seq techniques, respectively. Additionally, Pearson’s correlation analysis was used to establish correlations between differential hormones and growth indicators of Digitaria sanguinalis.Results and discussionThe results demonstrated that inoculation with Mortierella sp. MXBP304 effectively suppressed aboveground biomass and plant height in Digitaria sanguinalis. Furthermore, there was significant upregulation and downregulation in the expression of genes involved in the synthesis and metabolism of phenylalanine and L-phenylalanine. Conversely, the expression of genes related to tryptophan, L-tryptophan, and indole was significantly downregulated. The addition of Mortierella sp. MXBP304 can influence the gene expression associated with phenylalanine and tryptophan synthesis and metabolism during Digitaria sanguinalis growth, subsequently reducing the relative contents of phenylalanine and tryptophan, thereby directly inhibiting Digitaria sanguinalis growth.
Development and validation of a nomogram predictive model for cognitive impairment in cerebral small vessel disease: a comprehensive retrospective analysis
Authors: Li Ning , Gao Yan , Li Li-tao , Hu Ya-dong , Ling Li , Jia Nan , Chen Ya-jing , Meng Ya-nan , Jiang Ye 
Published: June 2024

BackgroundCerebral small vessel disease (CSVD) is a common neurodegenerative condition in the elderly, closely associated with cognitive impairment. Early identification of individuals with CSVD who are at a higher risk of developing cognitive impairment is crucial for timely intervention and improving patient outcomes.ObjectiveThe aim of this study is to construct a predictive model utilizing LASSO regression and binary logistic regression, with the objective of precisely forecasting the risk of cognitive impairment in patients with CSVD.MethodsThe study utilized LASSO regression for feature selection and logistic regression for model construction in a cohort of CSVD patients. The model’s validity was assessed through calibration curves and decision curve analysis (DCA).ResultsA nomogram was developed to predict cognitive impairment, incorporating hypertension, CSVD burden, apolipoprotein A1 (ApoA1) levels, and age. The model exhibited high accuracy with AUC values of 0.866 and 0.852 for the training and validation sets, respectively. Calibration curves confirmed the model’s reliability, and DCA highlighted its clinical utility. The model’s sensitivity and specificity were 75.3 and 79.7% for the training set, and 76.9 and 74.0% for the validation set.ConclusionThis study successfully demonstrates the application of machine learning in developing a reliable predictive model for cognitive impairment in CSVD. The model’s high accuracy and robust predictive capability provide a crucial tool for the early detection and intervention of cognitive impairment in patients with CSVD, potentially improving outcomes for this specific condition.
Sleep and mental health during the COVID-19 pandemic: findings from an online questionnaire survey in China
Authors: Liu Xuqian , Liu Mingyue , Ai Guangyuan , Hu Naijun , Liu Wenhan , Lai Chao , Xu Feng , Xie Zhaohong 
Published: June 2024

IntroductionThe online study investigated the sleep, psychological conditions, and risk factors during the wave of transmission of COVID-19 since December 7, 2022.MethodsWe distributed questionnaires through networking mediums to residents to gather information about COVID-19 infection, sleep, and mental status.ResultsDuring the extraordinary period in China, 91.9% of 1094 participants claimed to be infected with COVID-19, 36.8% reported poor sleep quality, 75.9% reported anxiety, and 65.5% reported depression. In retrospect, people have experienced lower sleep quality, longer sleep latency, enhanced rising time, and decreased sleep efficiency after the infection wave. After adjusting confounding factors, the elderly, women, urban residents, people with comorbidity, anxiety, depression, stress state, and COVID-19 infection have high risks for sleep disorders during the period.DiscussionThe survey indicates that sleep disturbance caused by COVID-19 involves multiple dimensions, such as physiology, psychology, and society. The COVID-19 infection-related sleep problem should be taken seriously. Apart from conventional treatment, psychological issues of insomnia can not be ignored.
Linking preterm infant gut microbiota to nasograstric enteral feeding tubes: exploring potential interactions and microbial strain transmission
Authors: Jara J. , Alba C. , Del Campo R. , Fernández L. , Sáenz de Pipaón M. , Rodríguez J. M. , Orgaz B. 
Published: June 2024

IntroductionPreterm birth is a growing problem worldwide. Staying at a neonatal intensive care unit (NICU) after birth is critical for the survival of preterm infants whose feeding often requires the use of nasogastric enteral feeding tubes (NEFT). These can be colonized by hospital-associated pathobionts that can access the gut of the preterm infants through this route. Since the gut microbiota is the most impactful factor on maturation of the immune system, any disturbance in this may condition their health. Therefore, the aim of this study is to assess the impact of NEFT-associated microbial communities on the establishment of the gut microbiota in preterm infants.Material and methodsA metataxonomic analysis of fecal and NEFT-related samples obtained during the first 2 weeks of life of preterm infants was performed. The potential sharing of strains isolated from the same set of samples of bacterial species involved in NICU's outbreaks, was assessed by Random Amplification of Polymorphic DNA (RAPD) genotyping.ResultsIn the samples taken 48 h after birth (NEFT-1 and Me/F1), Staphylococcus spp. was the most abundant genera (62% and 14%, respectively) and it was latter displaced to 5.5% and 0.45%, respectively by Enterobacteriaceae. Significant differences in beta diversity were detected in NEFT and fecal samples taken at day 17 after birth (NEFT-3 and F3) (p = 0.003 and p = 0.024, respectively). Significant positive correlations were found between the most relevant genera detected in NEFT-3 and F3. 28% of the patients shared at least one RAPD-PCR profile in fecal and NEFT samples and 11% of the total profiles were found at least once simultaneously in NEFT and fecal samples from the same patient.ConclusionThe results indicate a parallel bacterial colonization of the gut of preterm neonates and the NEFTs used for feeding, potentially involving strain sharing between these niches. Moreover, the same bacterial RAPD profiles were found in neonates hospitalized in different boxes, suggesting a microbial transference within the NICU environment. This study may assist clinical staff in implementing best practices to mitigate the spread of pathogens that could threaten the health of preterm infants.
Low-frequency weak electric field measurement based on Rydberg atoms using cavity-enhanced three photon system
Authors: Xiao Dongping , Shi Zhuxin , Chen Lin , Yan Sheng , Xu Lanxin , Zhang Huaiqing 
Published: June 2024

Introduction: Rydberg atoms are ideal for measuring electric fields due to their unique physical properties. However, low-frequency electric fields below MHz can be challenging due to the accumulation of ionized free electrons on the atomic vapor cell’s surface, acting as a shield.Method: This paper proposes a Cavity-enhanced three-photon system (CETPS) measurement scheme, which uses a long-wavelength laser to excite the Rydberg state, reducing atomic ionization and enhancing detection spectrum resolution. A theoretical model is proposed to explain the quantum coherence effect of the light field, measured electric field, and the atomic system.Result: The results show that the proposed scheme significantly increases the electromagnetically induced transparency (EIT) spectral peak and narrows the spectral width, resulting in the maximum slope increasing by more than an order of magnitude.Discussion: The paper also discusses the impact of the Rabi frequency of the two laser fields and the coupling coefficient of the optical cavity on the transmission spectrum amplitude and linewidth, along with the optimal configuration of these parameters in the CEPTS scheme.
The influence of body image on psychological symptomatology in breast cancer women undergoing intervention: a pre-post study
Authors: Verri Veronica , Pepe Ilaria , Abbatantuono Chiara , Bottalico Morena , Semeraro Cristina , Moschetta Marco , De Caro Maria Fara , Taurisano Paolo , Antonucci Linda Antonella , Taurino Alessandro 
Published: June 2024

IntroductionBody image concerns related to breast cancer surgery may challenge patients’ quality of life and their treatment outcomes, thus representing a key aspect to be assessed in the psycho-oncological settings. The present longitudinal study is aimed to (1) investigate the association between preoperative body image and postoperative psychological symptoms in breast cancer patients; (2) explore the impact of pre−/post-surgery variation in body image on psychological symptomatology.MethodsN = 72 women undergoing breast cancer surgery were preoperatively screened (T1) using the Body Uneasiness Test (BUT) and were assessed postoperatively (T2) using the Symptom Checklist-90 Revised (SCL-90-R) and re-administered the BUT. Spearman’s correlation was used to investigate the relationship between age, preoperative body image and postoperative psychological symptoms, and variation in body image. To predict post-surgical psychological symptomatology, two separated multiple regression models were used to evaluate preoperative body image and its variation after surgery controlling for covariates (i.e., education; intervention type). P significance was set as 0.05 for all analyses and adjusted for multiple comparisons.ResultsAt T1, anxiety in relation to body image scores emerged as the most frequently experienced psychological symptomatology after surgery (all adjusted p &lt; 0.05). Significant correlations were observed between all SCL-90-R scores at T2 and avoidance behaviors and depersonalization scores at T1. The associations were most significantly strong for somatization, depression, anxiety, and hostility (all adjusted p &lt; 0.05). However, change in body image between pre- and post-intervention was not associated with psychological symptomatology at T2 (all adjusted p &gt; 0.05). Pre-surgery body avoidance was significantly associated with post-intervention psychological symptoms (SOMβ = 0.453, p = 0.0001; DEPβ = 0.507, p = 0.0001; AXβ = 0.459, p = 0.0001; HOSβ = 0.410, p=. 0001). However, increased weight phobia between pre- and post-surgery was statistically associated with increased somatization, anxiety, depression and hostility at T2 (βSOM = 0.439, p = 0.0001; βDEP = 0.454, p = 0.0001; βANX = 0.471, p = 0.0001).DiscussionOverall, pre−/post-intervention body concerns were significantly associated with primary psychological symptoms in breast cancer patients undergoing surgery. Higher levels of body avoidance and weight phobia were significantly associated with the primary psychological dimensions assessed. As body concerns might act as quality-of-life predictors, their evaluation is crucial in fostering patients’ well-being and treatment adherence.
Construction of PARI public health education programs for Chinese undergraduates: a Delphi study
Authors: Kong Yuzhe , Xu Haitao , Li Chuyan , Yang Yang , Zhu Xiaoyi , Zuo Yu 
Published: June 2024

ObjectivesThe objective of this study is to develop a consensus among experts on a comprehensive and scientifically sound physical activity-related injuries (PARI) public health education program specifically tailored for undergraduates.MethodsThis study designed three rounds of expert consultation by using a Delphi method. A panel of 30 experts from the fields of public health education, sports medicine, anesthesia pain, emergency medicine, and emergency nursing participated in the study.ResultsThis study successfully established a consensus among experts on the goals, content, teaching methods, and time allocation for the PARI Public Health Education Program for undergraduates. The program encompasses 10 objectives divided into 2 main categories: professional knowledge and skill goals. In terms of content, it includes 5 primary indicators, 22 secondary indicators, and 56 detailed tertiary indicators. Six teaching methods were identified as suitable. Additionally, a typical 60-min educational session was segmented into eight parts, with a proposed time arrangement for each, ensuring comprehensive coverage of all topics.ConclusionThe consensus achieved in this study on the PARI Public Health Education Program for undergraduates lays a crucial foundation for the advancement of health literacy and proactive health management within this demographic. We presented a comprehensive framework for PARI public health education, integrating diverse learning methods and content areas. This systematic approach not only enriched the resources available for undergraduate health education, especially of PARI but also had the potential to significantly impact the implementation and effectiveness of health promotion strategies.
Dentifragilones A–B and Other Benzoic Acid Derivatives from the European Basidiomycete Dentipellis fragilis
Authors: Sum Winnie Chemutai , Ebada Sherif S. , Ibrahim Mahmoud A. A. , Kellner Harald , Stadler Marc 
Published: June 2024

A chemical and biological exploration of the European polypore Dentipellis fragilis afforded two previously undescribed natural products (1 and 2), together with three known derivatives (3–5). Chemical structures of the isolated compounds were confirmed through 1D/2D NMR spectroscopic analyses, mass spectrometry, and by comparison with the reported literature. The relative and absolute configurations of 1 were determined according to the ROESY spectrum and time-dependent density functional theory electronic circular dichroism (TDDFT-ECD), respectively. Furthermore, the absolute configuration of dentipellinol (3) was revisited and revealed to be of (R) configuration. All the isolated compounds were assessed for their cytotoxic and antimicrobial activities, with some being revealed to have weak to moderate antimicrobial activity, particularly against Gram-positive bacteria.
The Empire-Universe and Its area. On the Application of the Concept of State-Civilization to the History of Byzantium
Authors: Кузенков П.В. 
Published: June 2024

В современной науке все более широко и плодотворно разрабатывается концепт «государства-цивилизации», который в последнее время активно используется, в частности, в официальных документах. Именно в этом ракурсе следует, по нашему убеждению, вести анализ феномена Византийской империи. Это, в свою очередь, ставит ряд нетривиальных исследовательских задач, актуальных не только для исторической науки, но и для изучения современных цивилизационных процессов. Одной из таких задач является реконструкция политико-географических представлений, в рамках которых происходило становление и развитие военно-административных и церковных институций средневековой восточнохристианской цивилизации — «византийского мира». В тесной взаимосвязи с этой задачей находится и проблема выявления динамики соотношений политического, церковного и культурного планов в исторической географии Византии.
In modern science, the concept of «state-civilization» is being increasingly and fruitfully developed, which has recently been actively used, in particular, in official documents. It is from this perspective that, in our opinion, one should analyze the phenomenon of the Byzantine Empire. This, in turn, poses a number of nontrivial research problems that are relevant not only for historical science, but also for the study of modern civilizational processes. One of these tasks is the reconstruction of political and geographical ideas within which the formation and development of military-administrative and church institutions of the medieval Eastern Christian civilization — the «Byzantine world» — took place. Closely related to this task is the problem of identifying the dynamics of the relationships between the political, church and cultural plans in the historical geography of Byzantium.
Gender Perspectives on Job Satisfaction and Motivation Among Librarians: A Survey of National Library Services of Kenya
Authors: Ondabu Lilian , Njoroge Rose 
Published: June 2024

Job satisfaction is simply how a person feels regarding their work r job High sense of job satisfaction among librarians always results to higher productivity in Public libraries (Yaya, 2019). The study’s aim was to relate extensiveness of job satisfaction in Kenyan public libraries based on gender of the librarian. The study aims at finding out the gender perspectives on job satisfaction of librarians at Kenya National Library Service (KNLS). The study establish how pay, promotion, supervision and working conditions and gender affects job satisfaction and motivation between female and male librarians. Descriptive survey design method was adopted allow for an extensive review of the study phenomenon. Cluster sampling was used to select 8 KNLS branch libraries from the 8 regions in Kenya namely; Eastern, Western, Nairobi, Rift valley, Nyanza, North Eastern, Costal and Central region. Simple random sampling was applied to pick one library in regions with more than one KNLS branch libraries. The Sample size studied was made of 120 librarians; 69 female librarians and 51 male librarians. Primary data was collected using questionnaires from both female and male librarians at KNLS. Collected data was processed and analysed using descriptive and Pearson chi square was used to test the difference between female and male librarians’ perspectives on job satisfaction and motivation. The mean of job satisfaction on pay, promotion, supervision as well as working conditions were higher among the females (3.733, 3.9533, 39533 3.6286 respectively) than the males (3.6963, 3.8711, 3.9181 and 4.0357 respectively). The research findings indicate that there was no significant difference on job satisfaction between female and male librarians at Kenya National Library Service. The study also concluded that there is no significant difference in the overall job satisfaction. It is however essential that librarian are treated equally irrespective of their gender.
رقمنة المالية العامة وتأثيرها في فاعلية السياسة المالية تجارب مختارة مع إشارة خاصة الى العراق
Authors: الجابري قصي , المهداوي وفاء 
Published: June 2024

تٌعد رقمنة المالية العامة من أحدث التطورات الناجمة عن الثورة الصناعية الرابعة بما تتضمنه من ابتكارات تكنولوجية في شتى مجالات الإنفاق الحكومي وتحصيل الإيرادات الحكومية وصنع السياسات المالية . وتحاول دول العالم اتخاذ ما يلزم لرقمنة أدائها المالي في سبيل زيادة قدرتها على جمع المعلومات المالية بسرعة وسهولة واتخاذ القرارات من أجل زيادة فاعلية السياسة المالية نحو تحقيق أهدافها . ومن الدول الجديرة بالبحث هي دولة الأمارات العربية المتحدة والهند لكون هاتين الدولتين قد حصلتا على تصنيف متميز في مؤشر نضوج التكنولوجيا الحكومي إذ سيحاول البحث الكشف عن نقاط تميز هاتين التجربتين . كما تناول البحث التجربة العراقية في مجال رقمنة المالية العامة لتقييم هذه التجربة ولبيان إمكانية تطورها.