bluuebunny/crossref_metadata_2025_split huggingface dataset:
A brief intervention to improve food allergy knowledge among US pediatricians: lessons learned
Authors: Springston Elizabeth E. , Lau Claudia H. , Patel Parav , Warrier Manoj R. , Sohn Min‐Woong , Pongracic Jacqueline , Gupta Ruchi S. 
Published: July 2012

AbstractObjective:  To evaluate a brief educational tool for pediatricians developed to address known gaps in food allergy knowledge.Study Design:  Pre‐ and post‐assessments were administered to a convenience sample of 61 US pediatricians completing the Food Allergy Comprehension Tool between February and March of 2010. McNemar’s and Wilcoxon signed rank tests were used to determine whether clinical knowledge of food allergy and level of comfort in caring for food‐allergic children increased significantly after reviewing the tool. Logistic regression models were used to measure the association of participant characteristics with increased knowledge and comfort.Results:  Sixty‐one percent of surveyed physicians answered more knowledge questions correctly after reviewing the tool. Significantly more participants correctly indicated that anaphylaxis poses the greatest threat to teenagers rather than young children, and correctly rejected chronic nasal problems as a symptom of food allergy (p < 0.05). Comfort in caring for food‐allergic children increased significantly on all items post‐intervention (p < 0.05). Odds of increased knowledge and comfort were significantly higher among pediatricians without previous training in food allergy.Conclusion:  The Food Allergy Comprehension Tool is a rapid way to address known knowledge gaps among pediatricians and to identify areas in need of further intervention. We recommend integration of the tool with current food allergy guidelines.
Japonica cultivars' susceptibility to the rice water weevil Lissorhoptrus oryzophilus (Coleoptera: Curculionoidea: Brachyceridae)
Authors: Lupi D. , Giudici M. L. , Cenghialta C. , Rocco A. , Jucker C. , Colombo M. 
Published: July 2012

AbstractItaly is the largest rice‐producing country in the European Union. In Italy, only japonica cultivars are listed in the Italian National Register. Almost all of the rice production is concentrated in the Po Valley, where the rice water weevil Lissorhoptrus oryzophilus Kuschel was first detected and settled. This study investigated the performance of this pest in terms of feeding, reproduction and plant injury on 10 rice cultivars chosen among the most widely grown in Italy. No‐choice experiments were conducted to evaluate the plant susceptibility to larval attack and to find out how cultivars can influence the adult leaf area consumption. The results gave evidence of different types of attack depending on the density of the insect (0.6 adults/plant vs. 0.9 adults/plant), the cultivar type and climatic conditions. Different cultivars with the same level of infestation gave different results in terms of productivity. Production was significantly affected by the larval presence in 4 of the 10 cultivars tested. A different population structure reflected a different damage severity. Statistically different values for total adult leaf area consumption were found according to adult female age and to the cultivar.
Successful treatment of a patient with tumor necrosis factor receptor‐associated periodic syndrome using a half‐dose of etanercept
Authors: Kusuhara Koichi , Hoshina Takayuki , Saito Mitsumasa , Ishimura Masataka , Inoue Hirosuke , Horiuchi Takahiko , Sato Tetsuji , Hara Toshiro 
Published: July 2012

AbstractTNF receptor‐associated periodic syndrome (TRAPS) is caused by mutations of TNFRSF1A gene and characterized by recurrent febrile episodes of prolonged duration and initial good response to steroids. Etanercept, a TNF blocker, has been used as a putative molecular‐targeted agent for TRAPS, with some patients showing limited efficacy. Here, we report a patient with TRAPS who recovered from steroid dependency by etanercept and kept remission with a reduced dose of etanercept. The pathophysiology of TRAPS still remains to be elucidated and several hypotheses have been proposed. In the most recent hypothesis, the concerted action of wild‐type and mutant TNF receptors plays an important role in provoking enhanced inflammation in TRAPS. The excellent response to etanercept in our patient suggested that there is heterogeneity in TRAPS patients in terms of the contribution of normal TNF signaling to autoinflammation.
Atomoxetine improves communication in a girl with semantic‐pragmatic disorder
Authors: Inoko Kayo , Kodaira Kayano , Osawa Makiko 
Published: July 2012

AbstractThis report describes the case of an ADHD girl (hereafter referred to as K) with semantic‐pragmatic disorder, she was treated with atomoxetine. K was a 9‐year‐old girl. She had difficulty understanding words or sentences, finding words, and producing sentences. K also displayed symptoms of severe inattentiveness. K was diagnosed with DSM‐IV‐defined1 ADHD, predominantly the inattentive type. Her communication impairment was considered symptomatic of semantic‐pragmatic disorder. K was started on atomoxetine, the dose was increased to 50 mg/day (dosage based on weight: 1.8 mg/kg). Her communication activities were improved a few weeks after atomoxetine 50 mg/day was administered. She was unable to organize information pertaining to words, and so could not use words in expressive language. These problems were mitigated through the administration of atomoxetine. Further prospective studies are needed to better understand the therapeutic effects of atomoxetine in patients with semantic‐pragmatic disorder.
Myocarditis in a pediatric case of pandemic 2009H1N1 influenza
Authors: Jibiki Toshiaki , Sakamoto Ryota , Nakaya Mitsuru , Kanazawa Masaki , Gotoh Fumihiro , Yamaguchi Seiichi , Kutsuna Satoru , Hashimoto Yuji , Anzai Satoshi , Abe Katsuaki 
Published: July 2012

AbstractWe report a 6‐year‐old boy with no major disease history or allergic conditions initially presented with pneumonia, progressed to acute respiratory distress syndrome and acute myocarditis caused by pandemic 2009H1N1 influenza diagnosed with RT‐PCR testing, successfully managed with mechanical ventilation and percutaneous cardiopulmonary support system. Marked transient elevation of IgE in acute phase of the disease and the subsequent diagnosis of atopic asthma in our patient suggested a possible role of an underlying allergic condition in the clinicopathological process. Critically ill 2009H1N1‐infected patient with acute respiratory failure should carefully be physiologically monitored together with serial assessment of biomarkers aiming at a favorable cardiac outcome by giving the timely diagnosis and intervention.
Recovery of evidence‐based practice
Authors: Gordon Sarah E. , Ellis Pete M. 
Published: July 2012

ABSTRACTConsumer recovery is now enshrined in the national mental health policy of many countries. If this construct, which stems from the consumer/user/survivor movement, is truly to be the official and formal goal of mental health services, then it must be the yardstick against which evidence‐based practice (EBP) is judged. From a consumer‐recovery perspective, this paper re‐examines aspects of services chosen for study, methodologies, outcomes measures, and standards of evidence associated with EBP, those previously having been identified as deficient and in need of expansion. One of the significant differences between previous investigations and the present study is that the work, writing, perspectives, and advocacy of the consumer movement has developed to such a degree that we now have a much more extensive body of material upon which to critique EBP and inform and support the expansion of EBP. Our examination reinforces previous findings and the ongoing need for expansion. The consumer recovery‐focused direction, resources, frameworks, and approaches identified through the present paper should be used to expand the aspects of services chosen for study, methodologies, outcomes measures, and standards of evidence. This expansion will ultimately enable services to practice in a manner consistent with the key characteristics of supporting personal recovery.
MODEL‐BASED DIRECT ESTIMATION OF SMALL‐AREA DISTRIBUTIONS
Authors: Salvati Nicola , Chandra Hukum , Chambers Ray 
Published: July 2012

SummaryMuch of the small‐area estimation literature focuses on population totals and means. However, users of survey data are often interested in the finite‐population distribution of a survey variable and in the measures (e.g. medians, quartiles, percentiles) that characterize the shape of this distribution at the small‐area level. In this paper we propose a model‐based direct estimator (MBDE, Chandra and Chambers) of the small‐area distribution function. The MBDE is defined as a weighted sum of sample data from the area of interest, with weights derived from the calibrated spline‐based estimate of the finite‐population distribution function introduced by Harms and Duchesne, under an appropriately specified regression model with random area effects. We also discuss the mean squared error estimation of the MBDE. Monte Carlo simulations based on both simulated and real data sets show that the proposed MBDE and its associated mean squared error estimator perform well when compared with alternative estimators of the area‐specific finite‐population distribution function.
Repetition and Spacing Effects on True and False Recognition in the DRM Paradigm
Authors: DUBUISSON JEAN‐BAPTISTE , FIORI NICOLE , NICOLAS SERGE 
Published: July 2012

Dubuisson, J.‐B., Fiori, N. & Nicolas, S. (2012) Repetition and spacing effects on true and false recognition in the DRM paradigm. Scandinavian Journal of Psychology 53, 382–389.With the Deese‐Roediger‐McDermott (DRM) paradigm, the repetition effect on false memory had never been clarified. More importantly, the spacing effect on false memory was never directly investigated. So, we carried out two experiments to examine these effects on true and false recognition. In experiment 1, participants studied DRM lists which were presented one, three or five times. In experiment 2, we manipulated the repetition mode (massed vs. spaced with a short interval or a long interval) to explore the spacing effect. The results showed that true recognition increased monotonically with list repetition (experiment 1) and repetition spacing (experiment 2). The most striking finding was a similar spacing effect but no repetition effect on false recognition. Thus, these results were principally discussed in the light of the activation‐monitoring framework.
Youth Crime and Education Expansion
Authors: Machin Stephen , Vujić Sunčica , Marie Olivier 
Published: July 2012

Abstract
We present new evidence on the causal impact of education on crime, by considering a large expansion of the UK post-compulsory education system that occurred in the late 1980s and early 1990s. The education expansion raised education levels across the whole education distribution and, in particular for our analysis, at the bottom end enabling us to develop an instrumental variable strategy to study the crime- education relationship. At the same time as the education expansion, youth crime fell, revealing a significant cross-cohort relationship between crime and education. The causal crime reducing effect of education is estimated to be negative and significant, and considerably bigger in (absolute) magnitude than ordinary least squares estimates. The education boost also significantly impacted other productivity-related economic variables (qualification attainment and wages), demonstrating that the incapacitation effect of additional time spent in school is not the sole driver of the results.
Evaluation of 5‐Year Risk of Cardiovascular Events in Patients after Acute Myocardial Infarction Using Synchronization of 0.1‐Hz Rhythms in Cardiovascular System
Authors: Kiselev Anton R. , Gridnev Vladimir I. , Prokhorov Mikhail D. , Karavaev Anatoly S. , Posnenkova Olga M. , Ponomarenko Vladimir I. , Bezruchko Boris P. , Shvartz Vladimir A. 
Published: July 2012

Background: Synchronization between 0.1‐Hz rhythms in cardiovascular system is deteriorated at acute myocardial infarction (AMI) leading to a disruption of natural functional couplings within the system of autonomic regulation.Objective: This study evaluates the prognostic value of autonomic regulation indices for the 5‐year risk of fatal and nonfatal cardiovascular events in patients after AMI.Methods and Results: We studied 125 patients (53 [42%] female) after AMI aged between 30 and 83 years. The period of observation was 5 years with checkpoints at the first week after AMI and after each year after AMI. We compared the prognostic value of established clinical characteristics and degree S of synchronization between 0.1‐Hz rhythms in heart rate and microcirculation for evaluation of the 5‐year risk of mortality and recurrent myocardial infarction (MI) in patients after AMI. Acute heart failure Killip 2–4 at AMI and S < 20% at the first week after AMI were identified as the most important factors for evaluation of the risk of 5‐year mortality in patients after AMI (χ2= 14.2, P = 0.003). Sensitivity and specificity of low S (<20%) at the first week after AMI were 76% and 43%, respectively. For evaluation of the 5‐year risk of recurrent MI index S had no advantage over established clinical characteristics.Conclusion: The value of S below 20% in patients with AMI is a sensitive marker of high risk of mortality during the subsequent five years. It is characterized by better prognostic value than most of established clinical characteristics.
Enhancing the Reliability in the Noninvasive Measurement of the His Bundle Magnetic Field Using a Novel Signal Averaging Methodology
Authors: Senthilnathan Sengottuvel , Chandrasekaran Parasakthi , Narayanan Mariyappa , Patel Rajesh , Katholil Gireesan , Janawadkar Madhukar P. , Thimmakudy Radhakrishnan S. , Thoddi Muralidharan R. 
Published: July 2012

Background: Extraction of the weak electrical activity of the “His Bundle” (HB) by noninvasive methods has not been very successful in the past. The study reassesses the use of signal averaged magnetocardiography (SAMCG), overcoming some of the limitations in earlier studies including in the signal averaging methodology.Methods: SAMCG on healthy subjects (14 male and 1 female) were performed using R‐peak as the fiducial point in all cases and also using QRS‐onset as the fiducial point in select cases.Results: A conspicuous feature (H) with a magnitude up to 200 femto Tesla (fT) attributed to the HB activity was observed in the PR segment at several spatial positions on the thorax, with onset at 35–50 ms before the QRS‐onset (V) in 15 out of 18 trials constituting 83% of cases studied. The QRS‐onset as the fiducial point resolved the feature better compared to the conventionally used R‐peak, especially in trials exhibiting spread in heart rate (HR). This is attributed to the fluctuations in QonRD (the time interval between QRS‐onset and R‐peak) compared to the temporal stability of the H‐V duration.Conclusions: SAMCG reveals a well‐resolved H feature. The double hump morphology of the feature extended at least up to a frequency of 150 Hz. The importance of the choice of QRS‐onset as the fiducial point is unequivocally demonstrated, illustrated by measurements on subjects exhibiting considerable heart rate variability. The latter has a general validity and should be applicable to SAECG as well.
P‐Wave Morphologic Characteristics Predict Cardiovascular Events in a Community‐Dwelling Population
Authors: Kabutoya Tomoyuki , Ishikawa Shizukiyo , Ishikawa Joji , Hoshide Satoshi , Kario Kazuomi 
Published: July 2012

Background: There have been few reports on the relationship between P‐wave characteristics and long‐term cardiovascular events.Methods: A nested case‐control study was conducted as part of the Jichi Medical School cohort study, which enrolled 12,490 subjects in a community‐dwelling population. The mean follow‐up period was 10.7 years. The P‐wave characteristics of 526 patients who suffered cardiovascular events (fatal/nonfatal stroke, fatal/nonfatal myocardial infarction, and sudden death) within the follow‐up period (case group) were compared with those of 1578 matched controls (control group). The P‐wave morphology was classified as normal, deflected, and notched type in precordial leads. A broad P wave was defined as a maximum P‐wave duration of more than 120 ms in any of the 12 leads.Results: The mean age was 64 ± 8 years and the percentage of males was 54% in both groups. A notched P wave at baseline was observed in 10.1% of the case group and 6.0% of the control group (P = 0.001). A notched P wave was a significant predictor of cardiovascular events after adjustment for covariates (odds ratio = 1.59; 95% confidence interval = 1.08–2.33). Among the patients with left ventricular hypertrophy as evaluated by the Sokolow–Lyon criteria or Cornell product criteria, there was no significant difference in cardiovascular events between those with and those without a notched P wave, but in the absence of left ventricular hypertrophy, patients with a notched P wave suffered more cardiovascular events than those without a notched P wave by each criteria.Conclusion: P‐wave morphologic characteristics were effective for predicting cardiovascular events.
Synthesis of Porous Alumina Assisted by Resorcinol–Formaldehyde Gel
Authors: Chantam Pamornrat , Pavarajarn Varong 
Published: July 2012

Porous alumina with interconnected structure is synthesized by a simple approach assisted by a polycondensation of resorcinol–formaldehyde (RF) mixture. The results show significant increase in surface area because of the porous network of the RF gel and the effectiveness of the RF gel in retarding growth of alumina grains during calcination. The product obtained has the surface area of 68 m2/g even after the calcination at 1200°C to convert it to α‐alumina, whereas the surface area of the product prepared without the RF gel is only 10 m2/g. Nevertheless, the process is not direct templating technique since the interaction between the precursor of alumina, i.e., aluminum acetylacetonate (Al(acac)3), and the RF mixture occurs and alters the gel structure. The formation of alumina clusters via the sol‐gel process takes place as the network of RF gel is progressively formed.
What is pain? A phenomenological approach to understanding
Authors: Nay Rhonda , Fetherstonhaugh Deirdre 
Published: July 2012

nay r. & fetherstonhaugh d. (2012) What is pain? A phenomenological approach to understanding. International Journal of Older People Nursing7, 233–239  doi: 10.1111/j.1748‐3743.2012.00329.xPain is an individual experience. This paper presents four phenomenological accounts of pain which describe: the pain at the time of the experience; the meaning the pain had at the time of the experience (reflection in); and the meaning of the experience looking back on it (reflection upon). Specifically, the accounts describe pain that is emotional, cognitive and physical (acute and chronic). By exploring the essence of pain using very personal accounts, we encourage nurses to reflect on how their own understanding of pain and individual responses to pain can impact on how they in turn recognise, assess and manage pain in older people and especially those living with dementia. Paper 1 highlights the under‐assessment of pain in older people with dementia. By confronting readers with this paper’s phenomenological approach, it is hoped that they will be challenged to address this situation.
Pain and dementia – an application to practice: an example
Authors: Wall Sharon , White Tom 
Published: July 2012

wall s. & white t. (2012) Pain and dementia – an application to practice: an example. International Journal of Older People Nursing7, 227–232  doi: 10.1111/j.1748‐3743.2012.00330.xThere are fundamental clinical implications around assessment and evaluation of pain as well as management strategies for pain that have the potential of impacting and improving client outcomes. It is these principles that have been used to develop a training module on pain and dementia with widespread application to a range of settings. This study serves to provide an overview of this process as it translates evidence of pain in people living with dementia to practice for clinicians working in the field.
Pain and dementia: an overview of the literature
Authors: McAuliffe Linda , Brown Donna , Fetherstonhaugh Deirdre 
Published: July 2012

mcauliffe l., brown d. & fetherstonhaugh d. (2012) Pain and dementia: an overview of the literature. International Journal of Older People Nursing7, 219–226  doi: 10.1111/j.1748‐3743.2012.00331.xThis paper discusses how pain and its undertreatment impacts upon older people with dementia. It outlines how the contributing factors to the underassessment of pain are numerous and includes dementia‐related factors (such as loss of communication ability) and health professional–related factors (such as inappropriate or non‐application of a pain‐assessment tool and deficit knowledge regarding pain mechanisms and/or dementia). Pharmacological and non‐pharmacological treatment options for pain are noted as important but are not the focus of this paper.
The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post‐radiotherapy
Authors: Gunjur Ashray , Bressel Mathias , Ryan Gail 
Published: July 2012

AbstractIntroductionTo determine whether the pattern of progressive disease (PD) for glioblastoma multiforme (GBM) patients has changed with the introduction of the current standard of care protocol – postoperative conformal radiotherapy to a dose of 60 Gray in 30 fractions with concurrent low‐dose (75–100 mg/m2) temozolomide, followed by six cycles of adjuvant high‐dose (150–200 mg/m2) temozolomide – as compared with radiotherapy alone.MethodsFor GBM patients commencing combined modality treatment between October 2005 and August 2009, the MRI scan confirming progression (if any) was co‐registered with the original planning CT scan, and progression site(s) marked. Coverage of the composite progression volume (PDvol) by the original 95% prescription isodose volume was obtained from dose‐volume histogram (DVH) data, and assigned as ‘central’, ‘in field’, ‘marginal’ and ‘out of field’, corresponding to >95%, >80%, 20–80% and <20% coverage.ResultsOf 68 consecutive patients identified, 54 (79.4%) had documented PD. Of the 47 (87%) evaluable patients, 43 (91%) had in field progression with 36 (77%) of these being central. Of the remaining four cases, three (6%) had marginal progression, and only one patient (2%) had out of field progression. Median overall and progression‐free survival were 11.6 and 6.6 months, respectively.ConclusionThe pattern of progression in our GBM patients does not appear to have been altered by the addition of temozolomide. The overwhelming majority of first PD occurred within the original radiotherapy planning target volume, as is the case in patients treated with radiotherapy alone. Major changes to radiotherapy volumes are not indicated, with alternative strategies required to improve outcomes.