bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between Beighton score, genders, body mass index, and quadriceps angle in East Java Training Athletes
Authors: Sapril Abdul , Subadi Imam , Pawana I Putu Alit , Poerwandari Dewi , Wardani Nurul Kusuma , Melaniani Soenarnatalina 
Published: May 2024

Link of Video Abstract: https://youtu.be/BQ3uiW1O8GQ

Background: The quadriceps angle (Q-angle) affect the biomechanics of the lower extremities and is important in assessing the knee joint function. Increasing Q-angle can increase the risk of knee injury and also the chance of an athlete withdrawing from training or competition. Ligament laxity, gender, and high body mass index are proposed as risk factors for increasing Q-angle. Only a few research have investigated the correlation between these risk factors and Q-angle in competitive athletes, especially in Indonesia. This study aims to determine the correlation between Beighton score, genders, body mass index and Q-angle in competitive athletes in Indonesia.
Method: This study was a non-reactive study that used medical records from 94 competitive athletes collected to determine the subjects’ characteristics and research variables. The sampling technique was proportional random sampling. Ordinal regression tests were performed to assess the correlation between Q-angle and Beighton Score, Genders, and Body Mass Index in competitive athletes.
Result: There is a significant correlation between Beighton score and Q-angle in the supine position (p=0.000, R=2.829) and standing position (p=0.000, R=2.839), as well as body mass index and Q-angle in the supine position (p=0.003, R=0.23) and standing position (p=0.002, R=0.259), but there is no significant correlation between genders and Q-angle in the supine position (p=0.262, R=0.517) and standing position (p=0.235, R=0.550).
Conclusion: In competitive athletes, there is a strong correlation between Beighton score and Q-angle in both positions, as well as body mass index in both positions; nevertheless, there is no correlation between genders and Q-angle.
High-risk human papillomavirus prevalence among patients with cervical cancer at Moewardi General Hospital in Surakarta, Indonesia
Authors: Brian Wasita  , Suyatmi  , Riza Novierta Pesik  , Ratih Dewi Yudhani  , Nanang Wiyono  , Rachmi Fauziah Rahayu  , Kristanto Yuli Yarso  
Published: May 2024

Link of Video Abstract: https://www.youtube.com/watch?v=Ryf_-hvseVc

Introduction: In Indonesia, cervical cancer is the second most prevalent type of cancer among the general population. Cervical cancer has the second-highest mortality rate of all cancers. Infection with the Human Papilloma Virus (HPV) is one of the causes that starts the growing phase of cervical cancer. The purpose of this study, therefore, is to determine the prevalence of HPV infection in patients with cervical cancer who were examined at Dr. Moewardi Hospital and lived in the ex-Surakarta Residency.
Methods: Cervical tissue biopsy at the Anatomical Pathology Installation of Dr. Moewardi General Hospital Surakarta which had been diagnosed as cervical cancer was examined by the detection of E6 protein from HPV 16 and HPV 18 using immunohistochemical staining techniques. The data obtained would be analyzed based on the characteristics of the patient's age and the degree of histopathological malignancy with a p-value < 0.05 deemed significant.
Results: Overall, the prevalence of high-risk HPV infection was 77.8% (35/45), with women aged between 41-55 years having the highest prevalence of HPV infection (45.7, 16/35), followed by women aged 56-70 (42.9%), women over 70 (8.6%) and women under 40 (2.9%). The results of statistical tests showed that no significant relationship was found between HPV infection and age (p = 0.428). High-risk HPV infection was most prevalent in the poorly differentiated group (54.3%), followed by the well-differentiated group (34.3%) and the moderately differentiated group (11.4%). The results of statistical tests revealed a significant association between HPV infection and tumor grade (p = 0.027).
Conclusion: To lower patient morbidity and mortality, it is crucial to receive a prophylactic HPV vaccine due to the incidence of HPV 16 and 18 infections in patients with cervical cancer at the Regional Hospital Dr. Moewardi Surakarta, with a prevalence of 77.8%.
Factors attributed to depressive symptoms in women coping with infertility during the pandemic of COVID-19
Authors: Maidarti Mila , Bailie Emily , Siregar Aprilia , Garinasih Prini Diandara , Silvana Vita , Harzif Achmad Kemal , Pratama Gita , Sumapraja Kanadi , Muharam R , Hestiantoro Andon , Wiweko Budi 
Published: May 2024

Link of Video Abstract: https://youtu.be/2L4njgfd3SE

Background: The dissemination of coronavirus disease (COVID-19) has led to delayed infertility treatment and fear of contracting the virus which can affect the mental status of women with infertility. This research aimed to investigate whether fear, depression, perceptions, and knowledge related to COVID-19 affected infertility patients in seeking treatment and analyzed factors associated with depression during COVID-19 pandemic.
Method: This is a cross-sectional study utilizing an electronic survey distributed to infertility patients attending fertility services between May and July 2021. The primary outcomes were demographic characteristics, clinical parameters of infertility, depressive symptoms based on the Patient Health Questionnaire-9 (PHQ-9) score, and fear of COVID-19 scale (FCV-1 and FCV-2).
Results: A total of 533 patients were included. The fear of infertility treatment suspension due to COVID-19 was perceived by 34.1% of patients. The mean Patient Health Questionnaire-9 (PHQ-9) score was 4.55 ± 4.248, with mild depression occurring in 33.4% of patients. Low income, delayed treatment, and fear of COVID-19 scale (FCV-1) score together could significantly predict depression status. Despite the pandemic, 94.7% of patients decided to continue the treatment.
Conclusion: The COVID-19 pandemic has given rise to stressors that may aggravate the psychological condition of women with infertility. However, the enthusiasm to continue the treatment remains undisturbed. It is imperative to offer emotional support and address the consequences of COVID-19 infection in women with infertility during the pandemic era.
A patient with large ostium primum atrial septal defect who underwent open heart surgical closure with pericardial patch: a case report
Authors: Rampengan Starry Homenta , Rosmaningtyas Christina Ayu Ariani 
Published: May 2024

Introduction: Atrial septal defect (ASD) is one of the most common congenital heart diseases and often diagnosed in adulthood. ASD represents a spectrum of disease with symptoms that vary from asymptomatic to right-sided cardiac volume overload, pulmonary arterial hypertension and atrial arrhythmias depending on the size of the defect, size of the shunt and associated anomalies. We reported a patient with large ostium primum ASD who underwent surgical closure with a pericardial patch.
Case Description: A 18 years old man came with chief complaint of abnormal ECG results of the screening examination of police candidates from Bhayangkara Hospital Manado. The patient had no complaints during admission. The patient could still carry out daily activities without any obstacles. The patient also could do high intensity sport without complaints of shortness of breath, heavy chest, or headaches. .Electrocardiogram (ECG) examination showed sinus rhythm, heart rate 74 beats per minute, left anterior fascicular block (LAFB), complete right bundle branch block (RBBB) and fragmented QRS at inferior leads. Transthoracic and transesophageal echocardiography revealed large ostium primum ASD L-R shunt. Open heart ASD surgical closure with pericardial patch was done with good results and no residual shunt.
Conclusion: Large ostium primum ASD are associated with significant systemic-to-pulmonary shunts that results in desaturation requiring surgical closure. Large shunt of ASD patients who have a dilated right heart are associated with increased age-related morbidity and mortality. ASD with right heart dilatation should be considered for closure once the diagnosis is established regardless of the patient's age.
The correlation between interleukin-6 (IL-6) level and high sensitivity C-reactive protein (hs-CRP) level in acne vulgaris
Authors: Nauli Agnes , Putra Imam Budi , Jusuf Nelva Karmila 
Published: May 2024

Link of Video Abstract: https://youtu.be/nzfZMVQs6Cs

Background: Acne vulgaris (AV) is a common inflammation of the pilosebaceous unit. Inflammation is one of the four important factors in the genesis of AV. Interleukin-6 (IL-6) is a powerful major inducer of C-reactive protein (CRP) production and a proinflammatory cytokine. High sensitivity C-reactive protein (hs-CRP) levels can detect very low CRP concentrations. The purpose of this research is to ascertain whether the levels of IL-6 and hs-CRP in AV are related.
Methods: Forty-five subjects over 18 who had AV and 45 subjects who did not have AV served was included in this observational analytic research. IL-6 and hs-CRP levels are measured while the subject is examined, and basic statistics are recorded. Mann-Whitney and Spearman correlation tests were used to evaluate the data.
Results: In this study, AV was more dominant in women, consisting of 30 people (66.7%). The highest age in the study group was aged 18–22 years, comprising 25 people (56%). The mean IL-6 level in the AV group was 63.3 ng/L, and the control group, with an average value of 56.9 ng/L, showed a significant difference (p=0.014). There were substantial differences between the AV and control groups, as evidenced by the average hs-CRP levels of 5.48 ng/mL in the AV group and 4.27 ng/mL in the control group (p<0.001). Between the AV and control groups, there is a significant positive association between IL-6 and hs-CRP levels (r=0.700; p<0.001).
Conclusion: There is a strong correlation between IL-6 and hs-CRP levels in AV.
Community behavioral change and attitudes on the health protocol during the Covid-19 vaccination period and level 1 restriction (PPKM)
Authors: Sulistyowati Reny , Khoirunnisa  , Ardiyani Vissia Didin , Syam’ani  
Published: May 2024

Link of Video Abstract: https://youtu.be/j5NtdcbvTE4

Background: Concern for behavior change in compliance with health protocols during this pandemic continues to increase, especially when the coronavirus disease (COVID-19) vaccination is carried out. During the initial pandemic, the public perceived it as risky to be infected with COVID-19. However, this situation manifests itself in the emergence of a phase where public awareness of wearing masks, maintaining distance, and washing hands is decreasing. This study aimed to understand the impact of implementing the vaccine on the compliance behavior of wearing masks, washing hands, and keeping a distance, as well as attitudes towards behavior complying with health protocols during the COVID-19 vaccination period and the implementation of level 1 restriction on community activities (PPKM).
Method: We used a cross-sectional design, recruiting 110 respondents at the Menteng Primary Health Care Center, Palangka Raya City. Recruited patients were those over 18 years of age. This research instrument is an adaptation of several research questionnaires carried out in Indonesia, and we asked respondents using Indonesian.
Results: Of the 110 respondents, 59.1% were dominated by women, and 61.8% were in the 17-25 age group. A total of 106 respondents (96.4%) revealed that they had received information regarding health protocols. More than 70% obtained information from television (77.3%). Only half of the respondents received the 3rd dose or booster I. Knowledge was not the dominant factor influencing adherence to health protocols, but people's attitudes towards the Covid-19 health protocol. No relationship was found between knowledge and people's behavior toward health protocols.
Conclusion: Most of the respondents (80%) still adhere to health protocols as recommended by the government even though 74.5% of the people have received the 2nd and booster doses of the vaccine.
Impact of ability and willingness to pay for health insurance in Indonesia
Authors: Busyra Anwar , Ibrahim Roszita , Aizuddin Azimatun Noor , Hassan Nor Haty , Irwan Saputra  
Published: May 2024

Link of Video Abstract: https://youtu.be/w1aBTIalQSYOne way the community is financially protected from unforeseen health risks is through health insurance. The ability and willingness to pay for health insurance has been linked to improvements in public health, including better access to healthcare services, better public health, and financial protection from health risks, according to earlier research. Since 2014, Indonesia has had a government health insurance scheme under the National Health Insurance (JKN) program with the goal of enhancing community welfare and health access. However, despite the benefits provided by the JKN program, many people are still not registered and have not received benefits from the program. Recent studies have shown that high health insurance costs remain the main obstacle for people with low income to buy health insurance. The aim of this study was to identify the ability and willingness to pay for social insurance premiums in the framework of the National Health Insurance System. Utilizing the terms "impact of ability," "willingness," and "health insurance," the database search includes Google Scholar, ScienceDirect, and PubMed. The last step is to choose the articles that meet the criteria, which include being published between 2011 and 2022 and having the complete text accessible. The criteria for including 13 articles were met. According to the review's findings, the majority of publications link knowledge, income, how people view health care, and family support to health insurance payment compliance. Additionally, there are barriers and constraints affecting participation in National Health Insurance (NHI), such as registration procedures, benefits received, premiums, and private insurance ownership. There are several factors that affect compliance with health insurance payment, including knowledge, income, perception of health services, and family support.
Impact of preeclampsia on the outcome of COVID-19 infection
Authors: Djuanda Jonathan Kevin , Akbar M. Aldika , Sulistyono Agus , Aditya Rozi , Ernawati  
Published: May 2024

Link of Video Abstract: https://youtu.be/Pp9SqvVDzlw

Backgrounds: The COVID-19 outbreaks began at 2020 and spreading fast throughout the world. Infection in pregnancy is associated with increasing number of mortality and morbidity reports as well as increasing reports of preeclampsia (PE) cases complicating the cases. This study aimed to analyze the impact of preeclampsia on the outcome of COVID-19 patients during pregnancy and determine the effect of these variables on maternal and neonatal morbidity and mortality.
Methods: A retrospective study was performed on 711 COVID-19 patients admitted at Dr. Soetomo Hospital during 2020 - 2021. Demographic, clinical, laboratory, complication, and patient outcomes data were collected. Patients were then classified as COVID-19 with preeclampsia and COVID-19 without preeclampsia. Data were collected from hospital medical records, and statistical analysis was carried out to analyze these variables.
Results: We reported 711 pregnant patients with COVID-19, of which 510 patients (72%) had no preeclampsia and 201 patients (28%) had preeclampsia. There were statistically significant differences in maternal age, referral status, gestational age at admission, comorbidities, complications, and symptoms of COVID-19. COVID-19 with PE had higher comorbidities and severe performance than COVID-19 without PE : > 50% were preterm pregnancy, oxygen saturation < 90% on admission reported on 5.9% cases, 35.8% had symptoms, 20.4 % cases suffered severity/ critical condition, 24.4% need ventilation support. However, there was no significant difference in maternal death cases between COVID-19 with and without PE. Risk analysis shows an increased risk of morbidity in pregnant patients with COVID-19 infection: pulmonary edema, critical condition, ICU admission, and Ventilation needed with OR 18.9, 12.5, 5.1, and 2.7, respectively.
Conclusion: Preeclampsia increases the risk of morbidity in COVID-19 pregnant patients.
Comparative study on albumin, C-Reactive Protein (CRP) and D-dimer in chronic hemodialysis patients with COVID-19
Authors: Robinson Robinson , Pratama Kevin Gracia , Aditiawardana  
Published: May 2024

Link of Video Abstract: https://youtu.be/-i3vr4qpQUU

Background: Chronic kidney disease (CKD) patients on hemodialysis are more susceptible to COVID-19 infections. Mortality and morbidity rate are higher in this population. Thus, it is critical to understand which parameters are associated with mortality in this population. C-reactive protein (CRP), albumin, and d-dimer were shown in several studies to be associated with mortality in COVID-19-infected hemodialysis patients.
Methods: This study was a comparative observational, retrospective study from the medical records of Dr. Soetomo General Hospital in Surabaya, Indonesia. Chronic kidney disease patients on maintenance hemodialysis who tested positive for COVID-19 from June 2020 to January 2021 and underwent treatment in the isolation ward were included in this study. Data were analyzed using SPSS version 21.0 for Windows.
Results: The non-survivor groups have statistically significant lower albumin (2.78 (2.21-3.40) g/dL vs. 3.20 (2.45-3.80) g/dL; p=0.040) and higher CRP (10.40 (4.10-28.6) mg/L vs. 3.20 (0.10-80.0) mg/L; p=0.020) compared to the survivor group (Table 2). D-dimer value has no significant difference between the non-survivor and survivor groups (4,290 (190-18,310) ng/mL vs. 2,630 (190-19,430) ng/mL; p=0.140)
Conclusion: Non-survivor CKD patients with COVID-19 infections have significantly lower serum albumin and higher CRP concentrations. There is no significant difference in D-dimer concentrations in the survivor and non-survivor groups.
Epigallocatechin gallate effect on Interleukin-1 and MMP-9 expression as Pseudomonas aeruginosa keratitis adjuvant therapy
Authors: Urolita Tarosa Yodia , Fathimah Fariztah Sukainah Nur , Karima Annisa , Nurwasis  , Zuhria Ismi 
Published: May 2024

Link of Video Abstract: https://youtu.be/Ja9klXNlw5A

Background: Keratitis Pseudomonas aeruginosa is the most frequently occurring eye infection. It is a rapidly developing condition that can lead to ocular infections (endophthalmitis) and corneal perforation resulting in vision loss. Although prompt administration of antibiotics can effectively kill the bacteria, the corneal damage caused by toxins persists. The following inflammatory process results in corneal thinning, fibrosis, and eventual perforation.
Methods: This study is a literature review to support future experimental studies which will be conducted to examine the expression of IL-1b and MMP-9 on pseudomonas keratitis after administration of EGCG.
Results: Interleukin-1ß is a proinflammatory cytokine secreted by various immune cells in response to acute and chronic inflammation. At the same time, matrix metalloproteinase (MMP) is a group of proteolytic enzymes involved in the pathophysiology of various ocular surface diseases. Epigallocatechin gallate (EGCG) is the major polyphenol compound in green tea, produced from the Camellia sinensis plant. Recent studies suggest that EGCG has anti-inflammatory and antioxidant effects on various cell types, including the cornea. EGCG inhibits IL-1β, which induces the activation of the NF-kB signaling pathway, which may explain the decrease in uPA expression and the reduction of collagen degradation by corneal fibroblasts. EGCG inhibits the activation of pro-MMP 9 produced by corneal fibroblasts in response to IL-1β stimulation, and this effect is mediated by the inhibition of uPA upregulation without a significant impact on pro-MMP 9 expressions.
Conclusion: Epigallocatechin gallate (EGCG) in Camellia sinensis extract has the potential as an alternative adjuvant therapy for bacterial keratitis because it has antibacterial, anti-inflammatory and antioxidant effects.
Surgical epidemiology of spinal cord tumors at Dr. Kariadi Hospital, Semarang, Indonesia
Authors: Utomo Endi Suryo , Arianto Happy Kurnia Broto , Risdianto Ajid , Priambada Dody , Andar Erie Bambang Priyono Setyabudi , Muttaqin Zainal , Arifin Muhamad Thohar , Prihastomo Krisna Tsaniadi , Bakhtiar Yuriz 
Published: May 2024

Link of Video Abstract: https://youtu.be/JhROjWPKuAc

Background: Primary spinal cord tumors are rare central nervous system tumors that could develop at any age and have different management strategies based on the histopathological types. However, there is a lack of literature in Indonesia regarding the epidemiology and surgical treatment of patients with spinal cord tumors. This study aims to review and address the incidence of primary spinal cord tumors in Dr. Kariadi Hospital, Semarang.
Methods: A retrospective descriptive study was conducted using medical records of patients with spinal cord tumors at Dr. Kariadi Hospital, Semarang, Central Java, from 2019 to 2022. The frequency of each tumor, classified by gender, age, histologic type, anatomical position, and location based on vertebral segment, was analyzed to provide a descriptive result. Data were analyzed using SPSS version 25.0 for Windows.
Results: A total of 125 patients were identified with the mean age of patients being 43.95 ± 15.28 years old and a slight predominance of males (52.00%). Schwannoma (26.40%) and meningioma (24.80%) were the two most common histological types of tumors. Most of the tumor was intradural extramedullary (47.20%) and at the level of thoracic vertebrae (46.80%). The histologic type of the tumors was found to be associated with the patient’s age and the tumor’s anatomical position.
Conclusion: The incidence of spinal cord tumors in Dr. Kariadi Hospital, Semarang, is dominated by meningioma and schwannoma, mostly located at the thoracal level with an intradural extramedullary position. There is a significant association between the histological type of tumor and the patient's age and the location of the tumor
Subcutaneous emphysema and pneumocephalus following Ventriculoperitoneal Shunt (VPS) surgery for hydrocephalus: a case report
Authors: Parenrengi Muhammad Arifin , Hakim Muhammad Wildan , Suryaningtyas Wihasto 
Published: May 2024

Link Video Abstract: https://youtu.be/vfAwOXSjbCE

Background: Hydrocephalus is still commonly found in pediatric neurosurgery managed by endoscopic third ventriculostomy (ETV) and Ventriculoperitoneal Shunt (VPS). Subcutaneous emphysema and pneumocephalus as a complication of VPS surgery is rare. Subcutaneous emphysema is the presence of air in the skin, while pneumocephalus is the presence of air in the intracranial space. This case study aims to evaluate subcutaneous emphysema and pneumocephalus following ventriculoperitoneal shunt surgery for hydrocephalus.
Case Presentation: We report an 11-month-old girl with hydrocephalus due to aqueductal stenosis who postoperatively had subcutaneous emphysema and pneumocephalus. 1 week after VPS insertion, there was a crepitation under the skin of the neck and chest. The patient occasionally appeared breathless and had a fever. The respiratory rate increased with rales on the right lung, along with the gradually decreased consciousness, and the abdominal wound slowly became dehiscent. There was subcutaneous emphysema along the shunt track and pneumocephalus.
Conclusion: The interest, in this case, could be that of the patient’s other morbid conditions, including pneumonia and the dehiscent abdominal wound on the post-VP shunt insertion incision that may have also contributed to causing the subcutaneous emphysema and pneumocephalus.