bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel composite nanofilm of electropolymerization and self‐assembling on AA5052 surface as anticorrosion coating
Authors: Wang Fang , Liu Junjun , Li Yanni , Wang Yabin 
Published: September 2011

AbstractElectropolymerization nanofilm was prepared by cyclic voltammogram with 6N,N‐diallylamino‐1,3,5‐triazine‐2,4‐dithiol monosodium (DAN) on the AA5052 surface in 0.15M NaNO2 at 10°C, then octyl‐triethoxysilane (OTES) film was fabricated on the poly(6N,N‐diallylamino‐1,3,5‐triazine‐2,4‐dithiol) nanofilm (PDA) covered AA5052 surface by self‐assembling method to obtain the composite polymeric nanofilm (C‐PDA/OTES). The composite polymeric nanofilm was characterized by means of FTIR spectra, scanning electron microscope (SEM), contact angle, and potentiodynamic polarization. The results showed that the C‐PDA/OTES covered surface was more homogenous, compact, hydrophobic compared with PDA covered surface and had excellent protection efficiency. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Improving the thermal and mechanical properties of poly(propylene carbonate) by incorporating functionalized graphite oxide
Authors: Bian J. , Wei X.W. , Gong S. J. , Zhang H. , Guan Z. P. 
Published: September 2011

AbstractPoly(propylene carbonate) (PPC) is a new biodegradable aliphatic polycarbonate. However, the poor thermal stability, low glass transition temperatures (Tg), and relatively low mechanical property have limited its applications. To improve the thermal and mechanical properties of PPC, functionalized graphite oxide (MGO) was synthesized and mixed with PPC by a solution intercalation method to produce MGO/PPC composites. A uniform structure of MGO/PPC composites was confirmed by X‐ray diffraction and scanning electron microscope. The thermal and mechanical properties of MGO/PPC composites were investigated by thermal gravimetric analysis, differential scanning calorimetric, dynamic mechanical analysis, and electronic tensile tester. Due to the nanometer‐sized dispersion of layered graphite in polymer matrix, MGO/PPC composites exhibit improved thermal and mechanical properties than pure PPC. When the MGO content is 3.0 wt %, the MGO/PPC composites shows the best thermal and mechanical properties. These results indicate that nanocomposition is an efficient and convenient method to improve the properties of PPC. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Improvement of the interfacial adhesion between PBO fibers and PPESK matrices using plasma‐induced coating
Authors: Zhang Xiangyi , Chen Ping , Kang Xiaotao , Chen Mingxin , Wang Qian 
Published: September 2011

AbstractThis work deals with the plasma‐induced coating process on the surface of PBO fibers to obtain a strong interfacial adhesion between the poly(p‐phenylene benzobisoxazole) (PBO) fibers and the poly(phthalazinone ether sulfone ketone) (PPESK) matrices. The process consisted of four steps: (a) plasma preactivation of PBO fibers; (b) immersion in an epoxy resin solution; (c) drying and then soaking with the PPESK solution; (d) shaped by compression molding technique. The orthogonal experiments used in this study enable the determination of the significant experimental parameters that influence efficiency of the process by comparing the values of ILSS. The order of their influences was the concentration > power > treating time > treating pressure. The results of the interlaminar shear strength (ILSS) and water absorption showed that the ILSS of the composite increased by 56.5% after coating, meanwhile the water absorption declined to 0.32%. The changes of the surface chemical composition, the surface morphology, and the surface free energy of fibers were studied by FTIR spectroscopy, atomic force microscope (AFM), and dynamic contact angle analysis (DCAA), respectively. Fracture mechanism of the composite was examined by scanning electron microscope (SEM). The results indicated that plasma‐induced coating process was an efficient method to enhance the interfacial adhesion of PBO fibers and PPESK matrices. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Sequential interpenetrating polymer networks of novolac resin and poly(2‐ethyl hexyl acrylate)—thermal, mechanical, and morphological study
Authors: Goswami Sudipta , Maji Sanjoy K. 
Published: September 2011

AbstractInterpenetrating polymer networks (IPN) of novolac/poly (2‐ ethyl hexyl acrylate) (PEHA) have been prepared via in situ sequential technique of IPN formation. Full and semi‐IPNs were prepared with different blend ratios (w/w) e.g., 90 : 10, 80 : 20, and 70 : 30 in which the major constituent was novolac resin. A gradual decrease in specific gravity and hardness values was observed with increase in PEHA incorporation. A steady decrease in crosslink density with increase in PEHA fraction in the IPNs was quite evident. The IPNs were characterized with respect to their mechanical properties, e.g., ultimate tensile strength, percentage elongation at break, modulus, and toughness. Thermal behavior was studied by differential scanning calorimetry and thermogravimetric analysis. A plasticizing influence of PEHA on the rigid, brittle, and hard matrix of crosslinked phenolic resin is evidenced from the mechanical and thermal properties. The two‐phase surface morphology is revealed by scanning electron microscope. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
The water state in crosslinked poly(vinyl alcohol)–collagen hydrogel and its swelling behavior
Authors: Lin Hai , Dan Weihua , Dan Nianhua 
Published: September 2011

AbstractPoly vinyl alcohol (PVA) with pendent carboxyl group was synthesized and verified. The collagen was chemical crosslinked with the produced PVA under the help of crosslinker. Then, the PVA–collagen hydrogels were prepared through the repeated freezing–thawing. Since the water states in hydrogels play an important role in the performance of the product, thermogravimetric (TG) analysis and differential scanning calorimeter (DSC) were conducted to study the different states of water. The results indicated that the weight ratio of nonfreezable water to dry gel in PVA–collagen hydrogels was about 25%. Meanwhile, the swelling behaviors in distilled water and 0.9% saline were studied. The one‐phase exponential associate equation can fit the process very well. Calculated from the simulation equation, the swelling ratios at equilibrium in distilled water and saline were 14.353 g/g dry gel and 14.205 g/g dry gel, respectively. The results illustrated that the ions in solution would decrease the swelling ratio of the hydrogel. At the same time, the lyophilization might have slighter influence to the microstructure of hydrogels and should be more suitable for the swelling research than heat drying. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Synthesis and Anticancer Activity of 13‐Membered Cyclic Enediynes
Authors: Sharma Mukul , Joshi Mukesh C , Kumar Vineet , Malhotra Sanjay V. , Rawat Diwan S. 
Published: September 2011

AbstractWe herein describe the synthesis of 15 novel 13‐membered cyclic enediyne derivatives using simple and straightforward approach. Representative examples were screened for their anticancer activities on 60 different human tumor cell lines representing various histologies viz. leukemia, melanoma, and cancers of lung, colon, kidney, ovary, breast, prostate, and central nervous system. The enediyne derivatives with halogen substitutions, especially fluorides were found to be active against most of the cell lines. The initial results indicates marginal to good inhibition for the growth of tumor cells for several cell lines, which shows the potential of these class of compound towards anticancer application.
Primary central nervous system vasculitis presenting with intracranial hemorrhage
Authors: Salvarani Carlo , Brown Robert D. , Calamia Kenneth T. , Christianson Teresa J. H. , Huston John , Meschia James F. , Giannini Caterina , Miller Dylan V. , Hunder Gene G. 
Published: September 2011

AbstractObjectiveTo describe a subset of cases in a large retrospectively identified cohort of patients with primary central nervous system vasculitis (PCNSV) who present with intracranial hemorrhage.MethodsThe study consisted of a cohort of 131 consecutive patients with PCNSV who were seen at the Mayo Clinic over a 25‐year period from 1983 to 2007. The diagnosis of PCNSV was based on findings of brain or spinal cord biopsy, cerebral angiography, or both. Intracranial hemorrhage at presentation was defined as the presence of intracerebral or subarachnoid hemorrhage on computed tomography or magnetic resonance imaging (MRI) of the brain within 3 months of the date of PCNSV diagnosis. The clinical, laboratory, radiologic, and pathologic findings, therapy, and outcomes in patients presenting with intracranial hemorrhage were compared with those without intracranial hemorrhage.ResultsSixteen patients (12.2%) had evidence of intracranial hemorrhage at or near the time of diagnosis. Twelve patients had intracerebral hemorrhage, and 4 had subarachnoid hemorrhage. Twelve patients were diagnosed by findings on angiography and 4 by findings on CNS biopsy. Compared with the 115 patients without intracranial hemorrhage, the 16 patients presenting with intracranial hemorrhage were more frequently women, less frequently had altered cognition, a persistent neurologic deficit, or stroke at presentation, less frequently had MRI evidence of cerebral infarctions, and less frequently needed therapy at last followup. A necrotizing histopathologic pattern of vasculitis was observed in 3 of the 4 patients with positive biopsy findings (75%).ConclusionOur findings suggest that intracranial hemorrhage may not be an infrequent occurrence in early PCNSV. Necrotizing vasculitis may be a predominant histopathologic pattern.
A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease
Authors: Sawalha Amr H. , Hughes Travis , Nadig Ajay , Yılmaz Vuslat , Aksu Kenan , Keser Gokhan , Cefle Ayse , Yazıcı Ayten , Ergen Andaç , Alarcón‐Riquelme Marta E. , Salvarani Carlo , Casali Bruno , Direskeneli Haner , Saruhan‐Direskeneli Güher 
Published: September 2011

AbstractObjectiveUsing a genome‐wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behçet's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.MethodsWe studied a total of 676 Behçet's disease patients and 1,096 controls. The discovery set included 156 patients and 167 controls from Turkey, and the replication sets included 376 patients and 369 controls from Turkey and 144 patients and 560 controls from Italy. Genotyping of 14 single‐nucleotide polymorphisms (SNPs) within and around UBAC2 was performed using TaqMan SNP genotyping assays.ResultsThe genetic association between Behçet's disease and UBAC2 was established, replicated, and confirmed (meta‐analysis odds ratio 1.84, P = 1.69 × 10−7). Haplotype analysis identified both a disease‐risk haplotype and a protective haplotype (P = 0.00014 and P = 0.0075, respectively). Using conditional haplotype analysis, we identified the SNP rs7999348 (A/G) within UBAC2 as the most likely SNP with a genetic effect independent of the haplotypic effect formed by the remaining associated SNPs in this locus. Indeed, we demonstrated that rs7999348 tags a functional variant associated with increased messenger RNA expression of a UBAC2 transcript variant in peripheral blood mononuclear cells of individuals homozygous for the Behçet's disease–associated “G” allele. Further, our data suggested the possibility of multiple genetic effects that increase susceptibility to Behçet's disease in the UBAC2 locus.ConclusionWe established and confirmed the genetic association between UBAC2 and Behçet's disease in 3 independent sets of patients and controls. We identified the minor allele in rs7999348 as a disease‐risk allele that tags altered UBAC2 expression.
Localized expression of tenascin in systemic sclerosis–associated pulmonary fibrosis and its regulation by insulin‐like growth factor binding protein 3
Authors: Brissett Monique , Veraldi Kristen L. , Pilewski Joseph M. , Medsger Thomas A. , Feghali‐Bostwick Carol A. 
Published: September 2011

AbstractObjectiveTo determine the role of insulin‐like growth factor binding protein 3 (IGFBP‐3) in mediating the effects of transforming growth factor β (TGFβ) on tenascin‐C (TN‐C) production and to assess the levels of TN‐C in vivo in patients with systemic sclerosis (SSc)–associated pulmonary fibrosis.MethodsHuman primary lung fibroblasts were stimulated with TGFβ or IGFBP‐3 in the presence or absence of specific small interfering RNAs and chemical inhibitors of the signaling cascade. TN‐C levels in lung tissue specimens obtained from patients with SSc‐associated pulmonary fibrosis were assessed using immunohistochemical analysis and were compared with the levels in specimens obtained from normal donors. TN‐C levels were quantified in sera from normal donors and patients with SSc with or without pulmonary fibrosis, using an enzyme‐linked immunosorbent assay.ResultsIGFBP‐3 mediated the induction of TN‐C by TGFβ. Direct induction of TN‐C by IGFBP‐3 occurred in a p38 MAP kinase–dependent manner. TN‐C levels were abundant in lung tissues from patients with SSc and were localized to subepithelial layers of the distal airways. No TN‐C was detectable around the proximal airways. Patients with SSc‐associated pulmonary fibrosis had significantly higher levels of circulating TN‐C compared with SSc patients without pulmonary fibrosis. Longitudinal samples obtained from patients with SSc before and after the onset of pulmonary fibrosis showed increased levels of TN‐C after the onset of pulmonary fibrosis.ConclusionIGFBP‐3, which is overexpressed in fibrotic lungs, induces production of TN‐C by subepithelial fibroblasts. The increased lung tissue levels of TN‐C parallel the levels detected in the sera of SSc patients with pulmonary fibrosis, suggesting that TN‐C may be a useful biomarker for SSc‐related pulmonary fibrosis.
Treatment with tumor necrosis factor inhibitors and the risk of acute coronary syndromes in early rheumatoid arthritis
Authors: Ljung Lotta , Simard Julia F. , Jacobsson Lennart , Rantapää‐Dahlqvist Solbritt , Askling Johan ,   Anti‐Rheumatic Therapy in Sweden (ARTIS) Study Group
Published: September 2011

AbstractObjectiveRheumatoid arthritis (RA) is associated with an increased risk of ischemic heart disease, in both early and established RA. Data on the risk of ischemic heart disease in relation to therapy with tumor necrosis factor (TNF) antagonists (anti‐TNF) are conflicting in patients with established RA and essentially lacking in those with early RA. In established RA, the risk of myocardial infarction has been linked to the response to anti‐TNF therapies. The aim of this study was to determine the risk of acute coronary syndromes (ACS) in patients with early RA in relation to treatment with, and response to, anti‐TNF.MethodsA cohort consisting of patients in whom RA was diagnosed between 1999 and 2007 was identified from the Swedish Rheumatology Register (n = 6,000), from which information on disease activity and pharmacologic treatments was extracted. In a cohort study, the risk of first occurrence of an ACS was compared between patients treated with anti‐TNF and those without exposure to anti‐TNF, using hazard ratios (HRs). In a nested case–control study, the relationship between response to anti‐TNF according to the European League Against Rheumatism (EULAR) response criteria and the risk of ACS was investigated.ResultsIn the cohort study, treatment with anti‐TNF was not related to any statistically significant alteration in the risk of ACS (HR 0.80, 95% confidence interval [95% CI] 0.52–1.24). In the nested case–control study, a good or moderate EULAR treatment response at 3 months and at 6 months was not associated with a risk of ACS (odds ratio [OR] 1.7, 95% CI 0.5–5.1 and OR 1.5, 95% CI 0.3–6.9, respectively), when adjusted for disease activity before treatment start.ConclusionIn this study of patients treated with anti‐TNF within the first years of RA, neither treatment with, nor response to, anti‐TNF therapy could be linked to any statistically significant decrease in the risk of ACS.
The relationship of vibratory perception to dynamic joint loading, radiographic severity, and pain in knee osteoarthritis
Authors: Shakoor Najia , Lee Kristin J. , Fogg Louis F. , Wimmer Markus A. , Foucher Kharma C. , Mikolaitis Rachel A. , Block Joel A. 
Published: September 2011

AbstractObjectivePatients with knee osteoarthritis (OA) have been shown to have somatosensory deficits of the lower extremity. This study was designed to assess the association of these deficits with dynamic joint loading and their relationship to the structural and symptomatic severity of knee OA.MethodsSubjects with symptomatic knee OA underwent evaluation of the vibratory perception threshold (VPT) using a biothesiometer at 5 sites at the lower extremity. Dynamic joint loading was assessed through gait analyses. Knee pain was evaluated using a visual analog scale score for pain based on the Western Ontario and McMaster Universities OA Index. Radiographic severity of knee OA was assessed using the Kellgren/Lawrence (K/L) grading scale on radiographs obtained with the knee in a standing position.ResultsDynamic knee joint loading was directly associated with the VPT at the metatarsophalangeal (MTP) joint (Spearman's rho = 0.384, P = 0.033), indicating that the worse the vibratory sense, the higher the knee load during gait. The K/L severity grade was directly associated with the VPT at the MTP joint and lateral femoral condyle, after adjustment for age, sex, body mass index, and knee pain. After adjustment for confounders, there were no significant associations observed between the VPT and pain at any of the sites tested.ConclusionThese findings demonstrate an association between greater somatosensory deficits and higher dynamic loads in OA. They also demonstrate structural consequences associated with somatosensory deficits in OA, since the extent of sensory loss directly correlated with the radiographic severity of knee OA. However, there was no relationship observed between vibratory sense and symptomatic knee OA pain.
A new approach for Arabic text classification using Arabic field‐association terms
Authors: Atlam El‐Sayed , Morita Kazuhiro , Fuketa Masao , Aoe Jun‐ichi 
Published: September 2011

AbstractField‐association (FA) terms give us the knowledge to identify document fields using a limited set of discriminating terms. Although many earlier methods tried to extract automatically relevant FA terms to build a comprehensive dictionary, the problem lies in the lack of an effective method to extract automatically relevant FA terms to build a comprehensive dictionary. Moreover, all previous studies are based on FA terms in English and Japanese, and the extension of FA terms to other languages such as Arabic could benefit future research in the field. We present a new method to build a comprehensive Arabic dictionary using part‐of‐speech, pattern rules, and corpora in Arabic language. Experimental evaluation is carried out for various fields using 251 MB of domain‐specific corpora obtained from Arabic Wikipedia dumps and Alhayah news selected average of 2,825 FA terms (single and compound) per field. From the experimental results, recall and precision are 84% and 79%, respectively. We propose amended text classification methodology based on field association terms. Our approach is compared with Nave Bayes (NB) and kNN classifiers on 5,959 documents from Wikipedia dumps and Alhayah news. The new approach achieved a precision of 80.65% followed by NB (72.79%) and kNN (36.15%).
Z‐DNA Recognition in B‐Z‐B Sequences by a Cationic Zinc Porphyrin
Authors: D'Urso Alessandro , Holmes Andrea E. , Berova Nina , Balaz Milan , Purrello Roberto 
Published: September 2011

AbstractFor the first time it has been shown by spectroscopic studies such as circular dichroism and UV/Vis that cationic zinc porphyrin serves as a selective spectroscopic sensor that is able to recognize short left‐handed Z‐DNA tracts embedded in the B‐Z‐B sequences.
Desorption Dynamics, Internal Energies, and Imaging of Organic Molecules from Surfaces with Laser Desorption and Vacuum Ultraviolet (VUV) Photoionization
Authors: Kostko Oleg , Takahashi Lynelle K. , Ahmed Musahid 
Published: September 2011

AbstractThere is enormous interest in visualizing the chemical composition of organic material that comprises our world. A convenient method to obtain molecular information with high spatial resolution is imaging mass spectrometry. However, the internal energy deposited within molecules upon transfer to the gas phase from a surface can lead to increased fragmentation and to complications in analysis of mass spectra. Here it is shown that in laser desorption with postionization by tunable vacuum ultraviolet (VUV) radiation, the internal energy gained during laser desorption leads to minimal fragmentation of DNA bases. The internal temperature of laser‐desorbed triacontane molecules approaches 670 K, whereas the internal temperature of thymine is 800 K. A synchrotron‐based VUV postionization technique for determining translational temperatures reveals that biomolecules have translational temperatures in the range of 216–346 K. The observed low translational temperatures as well as their decrease with increased desorption laser power is explained by collisional cooling. An example of imaging mass spectrometry on an organic polymer by using laser‐desorption VUV postionization shows 5 μm feature details while using a 30 μm laser spot size and 7 ns pulse duration. Applications of laser‐desorption postionization to the analysis of cellulose, lignin, and humic acids are briefly discussed.
Synthesis and Applications of Tricarbonyliron Complexes of Dendralenes
Authors: Toombs‐Ruane Henry , Osinski Nik , Fallon Thomas , Wills Cindy , Willis Anthony C. , Paddon‐Row Michael N. , Sherburn Michael S. 
Published: September 2011

Abstract[3]Dendralene and [4]dendralene are converted smoothly into tricarbonyliron complexes. The structures of four complexes analyzed by DFT and single‐crystal X‐ray analysis show that, in contrast to free hydrocarbons, complexed dendralenes prefer a roughly in‐plane conformation. The complexes are stable towards Fe(CO)3 group migration up to 150 °C. The synthetic value of Fe(CO)3 complexation in the dendralene series is demonstrated through a variety of selective synthetic manipulations (Diels–Alder reaction, dipolar cycloaddition, Simmons–Smith cyclopropanation, dihydroxylation, olefin cross metathesis) that are not achievable by direct transformation of the free hydrocarbons. Application to the synthesis of a previously unreported, highly reactive linear/cross‐conjugated hydrocarbon is also described.
Simultaneous stabilization of full state information Linear Time‐Invariant systems
Authors: Galindo R. 
Published: September 2011

AbstractSingle necessary and sufficient stability conditions, are presented, for a common Linear Time‐Invariant (LTI) controller that simultaneously stabilizes each of a given family of LTI plants. It is assumed that the strictly proper, lumped and LTI plants have stabilizable realizations and are strongly stabilizable, and that the state‐space dimensions of the plants do not change, are even and are double the input‐space dimensions of the plants. The stabilizing controller is designed for a nominal plant and its free parameter is fixed assuring stability for all the plants, and assuring a stable controller. The stability conditions for simultaneous stabilization are based on the parity interlacing property, on a matrix that must be unimodular and on an analytical expression of the stabilizing controllers.Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society