bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Stereoselectivity in the Synthesis of 2‐Azetidinones from Ketenes and Imines via the Staudinger Reaction
Authors: Xu Jiaxi 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hybrid Antioxidants
Authors: Burlakova E. B. , Molochkina E. M. , Nikiforov G. A. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in the Use of Organozinc Halides
Authors: Hamilton Patrick N. , Burkhardt Elizabeth R. , Matos Karl 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: All Kinds of Reactivity: Recent Breakthroughs in Metal‐Catalyzed Alkyne Chemistry
Authors: Anaya de Parrodi Cecilia , Walsh Patrick J. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition‐Metal‐Catalyzed Enantioselective Synthesis of Compounds with Non‐Centrochirality
Authors: Ogasawara Masamichi , Watanabe Susumu 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Efforts Towards the Synthesis of the Complex Diterpene Providencin
Authors: Gaich Tanja , Weinstabl Harald , Mulzer Johann 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Deuteration in Organic Chemistry
Authors: Graening Timm 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Another Ten Stories in Antiviral Drug Discovery. Part C. “Old” and “New” Antivirals, Strategies, and Perspectives
Authors: De Clercq Erik 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in Exploring Heterocyclic Dienoxysilane Nucleophiles in Asymmetric Synthesis
Authors: Casiraghi Giovanni , Zanardi Franca , Battistini Lucia , Rassu Gloria 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermodynamics of Nanosystems with a Special View to Charge Carriers
Authors: Maier Joachim 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Photochromism Based on 6π‐Electrocyclization
Authors: Yokoyama Yasushi 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Kinetics of Protein Structural Changes
Authors: Marchal Stephane , Font Josep , Ribo Marc , Vilanova Maria , Phillips Robert S. , Lange Reinhard , Torrent Joan 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solid‐State Photophysical Properties and Functional Characteristics of Heterocyclic Quinol‐Type Fluorescent Hosts with Clathrate‐Forming Ability
Authors: Ooyama Yousuke , Yoshida Katsuhira 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isoflavonoids of the Leguminosae
Authors: Veitch Nigel C. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural and Functional Analogues of the Active Sites of the [Fe]‐, [NiFe]‐, and [FeFe]‐Hydrogenases
Authors: Tard Cedric , Pickett Christopher J. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optical Signatures of Molecular Dissymmetry: Combining Theory with Experiments to Address Stereochemical Puzzles
Authors: Mukhopadhyay Parag , Wipf Peter , Beratan David N. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Unified View of Surface‐Enhanced Raman Scattering
Authors: Lombardi John R. , Birke Ronald L. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Decreased cancer survival in individuals separated at time of diagnosis
Authors: Sprehn Gwen C. , Chambers Joanna E. , Saykin Andrew J. , Konski Andre , Johnstone Peter A. S. 
Published: August 2009

AbstractBACKGROUND:It long has been recognized that married patients have improved cancer survival when compared with unmarried patients. This has been postulated as being due to increased support, potentially leading to better compliance with therapy. Conversely, some data exist pointing to a relationship between marital discord and decreased immunity. We examined whether unmarried patients have a different prognosis by whether they are 1) never married, 2) divorced, 3) widowed, or 4) separated at time of diagnosis.METHODS:The public access data of the Surveillance, Epidemiology and End Results (SEER) registry were queried for cancer survival across all 17 registries between 1973 and 2004. SEER last updated data in April 2007. Records of 3.79 million patients were included in the analysis. We specifically analyzed 5‐year and 10‐year relative survival (RS; 5yRS, 10yRS), defined as observed survival divided by observed survival of an age‐matched, race‐matched, and gender‐matched population without disease, for all cancer patients by marital status, with specific subset analyses as indicated.RESULTS:Among unmarried patients, those separated at time of diagnosis had the lowest survival, followed by widowed, divorced, and never married patients. 5‐year and 10‐year RS of separated patients was 72% and 64% than that of married patients, respectively. This relationship persists when data are analyzed by gender.CONCLUSIONS:Separated marital status is associated with a significant decrement in cancer survival, even in comparison with other unmarried groups. While other socioeconomic variables could contribute to this phenomenon, further research into the immunologic correlates of the acutely stressful condition of marital separation should be conducted. Cancer 2009. © 2009 American Cancer Society.
Trends in survival after diagnosis with hematologic malignancy in adolescence or young adulthood in the United States, 1981‐2005
Authors: Pulte Dianne , Gondos Adam , Brenner Hermann 
Published: August 2009

AbstractBACKGROUND:There are few population‐based studies of long‐term survival of adolescents and young adults with hematologic malignancies; most pertain to patients diagnosed in the 1990s or earlier. Period analysis was used to obtain up‐to‐date information on survival expectations of adolescents and young adults diagnosed with hematologic malignancies through the early 21st century.METHODS:Period analysis was used to calculate 5‐ and 10‐year relative survival for adolescents and young adults diagnosed with Hodgkin lymphoma (HL), non‐Hodgkin lymphoma (NHL), acute lymphoblastic leukemia (ALL), acute myeloblastic leukemia (AML), and chronic myelocytic leukemia (CML) for 5 5‐year periods from 1981‐1985 to 2001‐2005, using data from the Surveillance, Epidemiology, and End Results database.RESULTS:Survival strongly improved for each of the 5 hematologic malignancies. Increases in 10‐year relative survival between 1981‐1985 and 2001‐2005 were as follows: HL, from 80.4% to 93.4%; NHL, from 55.6% to 76.2%; ALL, from 30.5% to 52.1%; AML, from 15.2% to 45.1%; CML, from 0 to 74.5% (P < .001 in all cases). However, although survival improved steadily throughout the period examined for the lymphomas and CML, survival was stable during the late 1990s and early 21st century for the acute leukemias.CONCLUSIONS:Survival expectations for adolescents and young adults with hematologic malignancies have strongly improved since the 1980s. However, with the exception of HL, survival rates have not reached the levels observed for children diagnosed with these malignancies, and survival expectations for patients with acute leukemia have stabilized at relatively low levels. Cancer 2009. © 2009 American Cancer Society.
Atomic Layer Deposition of Ta2O5/Polyimide Nanolaminates
Authors: Salmi Leo D. , Puukilainen Esa , Vehkamäki Marko , Heikkilä Mikko , Ritala Mikko 
Published: August 2009

AbstractTa2O5/polyimide nanolaminates are deposited at 170 °C by atomic layer deposition (ALD). The precursors are tantalum ethoxide and water for Ta2O5, and pyromellitic dianhydride (PMDA) and diaminohexane (DAH) for polyimide. The nanolaminates are characterized by X‐ray reflection (XRR), field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM), capacitance and current‐voltage measurements, and nanoindentation. The layered structure is confirmed by the XRR data and FESEM images. By controlling the relative thicknesses of the Ta2O5 and polyimide layers, the dielectric and mechanical properties of the nanolaminates are tailored over wide ranges. Dielectric properties of the nanolaminates are improved compared to bare Ta2O5 and polyimide films. Elasticity of the nanolaminate films increases with the polyimide content.
Organ patterning in the adult stage: The role of Wnt/β‐catenin signaling in liver zonation and beyond
Authors: Gebhardt Rolf , Hovhannisyan Amalya 
Published: August 2009

AbstractWnt/β‐catenin signaling has been found to play key roles in metabolic zonation of adult liver, regeneration, and hepatocellular carcinogenesis. In this review, recent progress in this field is summarized, in particular the rapidly growing knowledge about the various interactions of β‐catenin with many transcription factors involved in controlling metabolism. These interactions may provide the basis for understanding how the wide range of activities of Wnt/β‐catenin signaling is differentially interpreted. Based on these results, a three‐level mode for the molecular interpretation of β‐catenin activity gradients in liver is proposed favoring cell differentiation, metabolic zonation, and proliferation. While derangement of the combinatorial interplay of the various transcription factors with β‐catenin at the intermediary activity level may contribute to the development of metabolic diseases, extremely high activation of β‐catenin may eventually lead to initiation and progression of hepatocellular tumors. Developmental Dynamics 239:45–55, 2010. © 2009 Wiley‐Liss, Inc.
The trimeric G protein Go inflicts a double impact on axin in the Wnt/frizzled signaling pathway
Authors: Egger‐Adam Diane , Katanaev Vladimir L. 
Published: August 2009

AbstractThe Wnt/Frizzled signaling pathway plays crucial roles in animal development and is deregulated in many cases of carcinogenesis. We and others have previously demonstrated that Frizzled proteins initiating the intracellular signaling are typical G protein–coupled receptors and rely on the trimeric G protein Go for Wnt transduction in Drosophila. However, the mode of action of Go and its interplay with other transducers of the pathway such as Dishevelled and Axin remained unclear. Here we show that the α‐subunit of Go directly acts on Axin, the multidomain protein playing a negative role in the Wnt signaling. Gαo physically binds Axin and re‐localizes it to the plasma membrane. Furthermore, Gαo suppresses Axin's inhibitory action on the Wnt pathway in Drosophila wing development. The interaction of Gαo with Axin critically depends on the RGS domain of the latter. Additionally, we show that the βγ‐component of Go can directly bind and recruit Dishevelled from cytoplasm to the plasma membrane, where activated Dishevelled can act on the DIX domain of Axin. Thus, the two components of the trimeric Go protein mediate a double—direct and indirect—impact on different regions of Axin, which likely serves to ensure a robust inhibition of this protein and transduction of the Wnt signal. Developmental Dynamics 239:168–183, 2010. © 2009 Wiley‐Liss, Inc.
Xenopus Insm1 is essential for gastrointestinal and pancreatic endocrine cell development
Authors: Horb Lori Dawn , Jarkji Zeina H. , Horb Marko E. 
Published: August 2009

AbstractIn mammals, it has been well established that gastrointestinal and pancreatic endocrine cells are specified by a cascade of different transcription factors, but whether these same pathways (or linear relationships) operate in Xenopus is currently unknown. We recently identified the endocrine‐specific zinc finger transcription factor insulinoma associated protein 1 (insm1) as a dorsal‐enriched gene. We found that insm1 is expressed in the dorsal pancreas as early as NF28, making it one of the earliest markers to be localized to the dorsal pancreas. Through morpholino‐mediated knockdown, we demonstrate that insm1 is essential for proper specification of both gastrointestinal and pancreatic endocrine cells. In addition, we place insm1 downstream of ngn3 and upstream of pax6 and neuroD in the endocrine cell transcription factor cascade. These are the first results showing that the endodermal endocrine cell development in Xenopus uses the same transcriptional cascade as in mammals. Developmental Dynamics 238:2505–2510, 2009. © 2009 Wiley‐Liss, Inc.
Platelet‐derived growth factor is involved in the differentiation of second heart field‐derived cardiac structures in chicken embryos
Authors: Bax Noortje A.M. , Lie‐Venema Heleen , Vicente‐Steijn Rebecca , Bleyl Steven B. , Van Den Akker Nynke M.S. , Maas Saskia , Poelmann Robert E. , Gittenberger‐de Groot Adriana C. 
Published: August 2009

AbstractFor the establishment of a fully functional septated heart, addition of myocardium from second heart field‐derived structures is important. Platelet‐derived growth factors (PDGFs) are known for their role in cardiovascular development. In this study, we aim to elucidate this role of PDGF‐A, PDGF‐C, and their receptor PDGFR‐α. We analyzed the expression patterns of PDGF‐A, ‐C, and their receptor PDGFR‐α during avian heart development. A spatiotemporal pattern of ligands was seen with colocalization of the PDGFR‐α. This was found in second heart field‐derived myocardium as well as the proepicardial organ (PEO) and epicardium. Mechanical inhibition of epicardial outgrowth as well as chemical disturbance of PDGFR‐α support a functional role of the ligands and the receptor in cardiac development. Developmental Dynamics 238:2658–2669, 2009. © 2009 Wiley‐Liss, Inc.
Cardiac neural crest and outflow tract defects in Lrp6 mutant mice
Authors: Song Lanying , Li Yunhong , Wang Kai , Zhou Chengji J. 
Published: August 2009

AbstractThe role of a key Wnt coreceptor Lrp6 during heart development remains unclear. Here we show that ablation of Lrp6 in mice causes conotruncal anomalies including double‐outlet right ventricle (DORV), outflow tract (OFT) cushion hypoplasia, and ventricular septal defect (VSD). Cardiac neural crest cells are specifically lost in the dorsal neural tube and caudal pharyngeal arches of the mutant embryos. We also demonstrate that Lrp6 is required for proliferation and survival of cardiac progenitors and for the expression of Isl1 in the secondary heart field. Other known cardiogenic regulators such as Msx1, Msx2, and Fgf8 are also significantly diminished in the mutant pharyngeal arches and/or OFT. Unexpectedly, the myocardium differentiation factors Mef2c and Myocardin are upregulated in the mutant OFT. Our results indicate that Lrp6 is essential for cardiac neural crest and OFT development upstream of multiple important cardiogenic genes in different cardiac lineage cells during early cardiogenesis. Developmental Dynamics 239:200–210, 2010. © 2009 Wiley‐Liss, Inc.
Enucleation of feeder cells and egg cells with psoralens
Authors: McGarry Thomas J. , Bonaguidi Michael , Lyass Ljuba , Kessler John A. , Bodily Jason M. , Doglio Lynn 
Published: August 2009

AbstractThe cell nucleus must be inactivated or destroyed in order to generate feeder layers for cultured cells or to prepare recipient egg cells for nuclear transfer. Existing enucleation techniques are either cumbersome or employ toxic chemicals. Here we report a new method to enucleate cells by treatment with a psoralen and long‐wave ultraviolet light. The technique is >90% efficient and causes little cytoplasmic damage to the treated cell. We have used psoralen treatment to enucleate a wide variety of cells, including eggs, sperm, HeLa cells, and fibroblasts. Colonies of human embryonic stem cells (hESCs) and human keratinocyte precursors grown on psoralen‐treated feeders are indistinguishable from those grown on gamma‐irradiated or mitomycin C‐treated cells. Psoralen enucleation provides a rapid, simple, and non‐toxic method to generate feeder cells. The technique is also useful for nuclear transfer studies in species with large eggs whose cleavage divisions are not regulated by cell‐cycle checkpoints. Developmental Dynamics 238:2614–2621, 2009. © 2009 Wiley‐Liss, Inc.
Water‐Soluble Calix[4]resorcinarenes with Hydroxyproline Groups as Chiral NMR Solvating Agents for Phenyl‐ and Pyridyl‐Containing Compounds
Authors: Hagan Kaitlin A. , O'Farrell Courtney M. , Wenzel Thomas J. 
Published: August 2009

AbstractA series of water‐soluble sulfonated calix[4]resorcinarenes with L‐proline, cis‐4‐hydroxy‐d‐ and ‐L‐proline, trans‐4‐hydroxy‐L‐proline and trans‐3‐hydroxy‐L‐proline are evaluated as chiral NMR solvating agents. The changes in chemical shifts and enantiomeric discrimination in the 1H NMR spectra of a variety of phenyl‐ and pyridyl‐containing compounds are reported. Substrates associate by insertion of the phenyl or pyridyl ring into the cavity of the calix[4]resorcinarene. Series of compounds with methylbenzylamine and benzyl alcohol units are among those examined. For many compounds, the calix[4]resorcinarenes with the hydroxyproline groups are more effective chiral NMR solvating agents than the corresponding proline derivative. The trans‐4‐ and trans‐3‐hydroxy‐L‐proline derivatives are especially effective as chiral NMR solvating agents. Enantiomeric discrimination in the 1H NMR spectra is often large enough to facilitate the analysis of enantiomeric purity.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
A Novel Way to Improve Sulfate Recognition
Authors: Shishkanova Tatiana V. , Sykora David , Vinšová Hana , Král Vladimír , Mihai Iulia , Gospodinova Natalia P. 
Published: August 2009

AbstractWe report a novel way to improve the recognition of highly hydrated sulfate anions. It is shown that polyaniline (PANI) layer deposited on the poly(vinyl chloride) (PVC) membrane favors transport of highly hydrated anions due to stronger PANI hydration in their presence.
Polymeric Membrane Ion‐Selective Electrode for Butyrylcholinesterase Based on Controlled Release of Substrate
Authors: Ding Jiawang , Qin Wei 
Published: August 2009

AbstractA butyrylcholine selective polymeric membrane electrode using o‐β‐cyclodextrin as ionophore is described as a reagent controlled‐release system for reagentless detection of butyrylcholinesterase. Butyrylcholine released across the membrane from inner filling solution of the ion selective electrode is consumed by reaction of the enzyme in sample solution and the concentration of butyrylcholine at the membrane surface can be sensed potentiometrically. The electrode with 0.01 M butyrylcholine in the inner solution yields a potential that varies linearly with butyrylcholinesterase concentration over the range of 0.0075–0.15 U mL−1 in 0.02 M of pH 7.4 sodium phosphate buffer solution. This approach can also be used to analyze butyrylcholinesterase inhibitors such as organophosphate pesticides. The inhibition percentage of parathion is proportional to its concentration in the range of 0.05–0.5 ng mL−1 with a detection limit of 0.03 ng mL−1.