bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can slide positivity rates predict malaria transmission?
Authors: Bi Yan , Hu Wenbiao , Liu Huaxin , Xiao Yujiang , Guo Yuming , Chen Shimei , Zhao Laifa , Tong Shilu 
Published: April 2012

Abstract

Background
Malaria is a significant threat to population health in the border areas of Yunnan Province, China. How to accurately measure malaria transmission is an important issue. This study aimed to examine the role of slide positivity rates (SPR) in malaria transmission in Mengla County, Yunnan Province, China.

Methods
Data on annual malaria cases, SPR and socio-economic factors for the period of 1993 to 2008 were obtained from the Center for Disease Control and Prevention (CDC) and the Bureau of Statistics, Mengla, China. Multiple linear regression models were conducted to evaluate the relationship between socio-ecologic factors and malaria incidence.

Results
The results show that SPR was significantly positively associated with the malaria incidence rates. The SPR (β = 1.244, p = 0.000) alone and combination (SPR, β = 1.326, p < 0.001) with other predictors can explain about 85% and 95% of variation in malaria transmission, respectively. Every 1% increase in SPR corresponded to an increase of 1.76/100,000 in malaria incidence rates.

Conclusion
SPR is a strong predictor of malaria transmission, and can be used to improve the planning and implementation of malaria elimination programmes in Mengla and other similar locations. SPR might also be a useful indicator of malaria early warning systems in China.
Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers
Authors: Yang Xiaohong R , Figueroa Jonine D , Falk Roni T , Zhang Hong , Pfeiffer Ruth M , Hewitt Stephen M , Lissowska Jolanta , Peplonska Beata , Brinton Louise , Garcia-Closas Montserrat , Sherman Mark E 
Published: April 2012

Abstract
Introduction
Involution of terminal duct lobular units (TDLUs), the structures that give rise to most breast cancers, has been associated with reduced breast cancer risk. Data suggest that the etiology and pathogenesis of luminal A and core basal phenotype (CBP) breast cancers differ, but associations with TDLU involution are unknown. Accordingly, we performed a masked microscopic assessment of TDLU involution in benign tissues associated with luminal A and CBP breast cancers diagnosed among women less than age 55 years.

Methods
Cases were participants in a population-based case-control study conducted in Poland. Increased TDLU involution was defined as fewer acini per TDLU or shorter TDLU diameter. Luminal A was defined as estrogen receptor (ER) positive and/or progesterone receptor (PR) positive and human epidermal growth factor receptor 2 (HER2) negative and CBP as negative for ER, PR, and HER2 with expression of basal cytokeratins or epidermal growth factor receptor (EGFR). We performed logistic regression to evaluate associations between TDLU involution and tumor subtypes, adjusted for clinical characteristics and breast cancer risk factors.

Results
Among 232 luminal A and 49 CBP cancers associated with evaluable TDLUs, CBP tumors were associated with significantly greater average number of acini per TDLU (odds ratio (OR) = 3.36, 95% confidence interval (CI) = 1.36 to 8.32, P = 0.009) and larger average TDLU diameter (OR = 2.49, 95% CI = 1.08 to 5.74, P = 0.03; comparing highest to lowest group, adjusted for age and study site).

Conclusions
We suggest that TDLU involution is less marked in benign tissues surrounding CBP as compared to luminal A cancers, which may reflect differences in the etiology and pathogenesis of these tumor subtypes.
Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study
Authors: Terblanche Marius , Kruger Peter , Gangi Stefania di , Gearay Sadiq , Gilfeather Lynn , Ferguson Niall D , Pearse Rupert , Beale Richard , Rhodes Andrew , Brett Stephen J , McAuley Daniel F 
Published: April 2012

Abstract
Introduction
Many supposed low-risk intensive care unit (ICU) admissions develop acute organ failure (AOF). Identifying patients at high risk of developing AOF and targeting them with preventative strategies may be effective. Our study question was: in a population of ICU patients receiving positive pressure respiratory support (invasive or non-invasive) in the absence of non-respiratory AOF, what is the 14-day incidence of, risk factors for and time to acute organ failure?

Methods
In an international prospective cohort study, patients receiving positive pressure respiratory support (invasive or non-invasive) in the absence of non-respiratory AOF were enrolled and followed for 14 days. The primary outcome measure was the incidence of any AOF (defined as SOFA 3 to 4) during follow-up.

Results
A total of 123 of 766 screened patients (16.1%) were enrolled. Data are reported for 121 patients. In total, 45 out of 121 patients (37.2%) developed AOF. Mortality rates were higher in those with AOF: 17.8% versus 4.0% OR 5.11, P = 0.019) for ICU mortality; and 28.9% versus 11.8% (OR 2.80, P = 0.019) for hospital mortality. Median ICU length of stay was also longer in those with AOF (11 versus 3.0 days; P < 0.0001). Hypoxemic respiratory failure (P = 0.001) and cardiovascular dysfunction (that is, SOFA 1 to 2; P = 0.03) were associated with AOF. The median time to first AOF was two days.

Conclusions
Patients receiving positive (invasive or non-invasive) pressure respiratory support in the absence of non-respiratory AOF are commonly admitted to ICU; AOF is frequent in these patients. Organ failure developed within a short period after admission. Hypoxemic respiratory failure and cardiovascular dysfunction were strongly associated with AOF.
Safety of Low Doses of Quetiapine When Used for Insomnia
Authors: Coe Holly V , Hong Irene S 
Published: April 2012

Objective: To evaluate the safety of low doses of quetiapine when used for insomnia. Data Sources: A literature search was performed using PubMed and EMBASE (January 1990-November 2011) using the terms quetiapine, insomnia, sleep, low-dose, subtherapeutic, safety, and weight gain. Study Selection And Data Extraction:: Two prospective trials were identified that evaluated the effect of quetiapine in primary insomnia. In addition, 2 retrospective cohort studies were identified that evaluated the safety of low doses of quetiapine when used for Insomnia. Several case reports on adverse effects with low doses of the drug were also Included. Data Synthesis: Quetiapine is commonly used off-label for treatment of insomnia. When used for sleep, doses typically seen are less than the Food and Drug Administration-recommended dosage of 150-800 mg/day; those evaluated in the studies reviewed here were 25-200 mg/day). At recommended doses, atypical antipsychotics such as quetiapine are associated with metabolic adverse events (diabetes, obesity, hyperlipidemia). Adverse effects in the prospective trials were patient-reported and were minor, including drowsiness and dry mouth; however, tha trials were limited by their small sample size and short duration. The retrospective cohort studies found that quetiapine was associated with significant increases in weight compared to baseline. Serious adverse events identified from case reports included fatal hepatotoxicity, restless legs syndrome, akathisia, and weight gain. Conclusions: There are potential safety concerns when using low-dose quetiapine for treatment of insomnia. These concerns should be evaluated in further prospective studies. Based on limited data and potential safety concerns, use of low-dose quetiapine for insomnia is not recommended.
Factors Associated with Reported Preventable Adverse Drug Events: A Retrospective, Case-Control Study
Authors: Beckett Robert D , Sheehan Amy Heck , Reddan Jennifer G 
Published: April 2012

Background: It has been reported that error occurs at some point during the medication use process in approximately 6% of medication doses administered in the inpatient setting. An estimated 1-10% of medication errors lead to patient harm; however, factors affecting the risk of harm from a medication error are undefined in the literature. Objective: To identify independent factors affecting the risk of reported preventable adverse drug events (ADEs) (ie, medication errors contributing to patient harm) compared to medication errors that did not contribute to patient harm in a diverse patient population. Methods: This was a retrospective, case-control study conducted at 3 hospitals within a large health system. Medication error reports from July 1, 2009, through June 30, 2010, were assessed. All reported medication errors determined to have contributed to patient harm were matched 1:1 with a medication error that did not contribute to harm. Data collected through review of the incident report and medical record included patient, provider, medication, and other related factors. Multivariable logistic regression was used to determine the relationship of potential factors to patient harm. Results: Of 4321 medication errors reported at study sites, 182 (4%) contributed to patient harm. Factors associated with increased independent risk of harm were 30-day readmission, time of day 0300-0659, and Institute for Safe Medication Practices (ISMP) high-alert medications. Factors associated with decreased independent risk of harm were multiple medication errors, occurrence during February or April, dispensing errors, and pharmacist review of medication order. Conclusions: Health systems should develop programs to promote safe, conscientious use of ISMP high-alert medications, promote pharmacist review, control the use of cabinet overrides, and direct provider attention toward recently admitted patients. Efforts should be made to determine factors associated with risk of harm at local levels.
On the Complexation of Some Divalent Metal Cations with Beauvericin in Nitrobenzene Saturated with Water
Authors: Makrlík Emanuel , Selucký P. , Vaňura P. , Toman Petr 
Published: April 2012

Abstract
From extraction experiments and γ-activity measurements, the exchange extraction constants corresponding to the general equilibrium M2+(aq)+1·Sr2+(nb)⇆1·M2+(nb)+ Sr2+(aq) taking place in the two–phase water-nitrobenzene system (M2+ߙ=ߙMg2+, Ca2+, Ba2+, Pb2+, Zn2+, Mn2+; 1ߙ=ߙbeauvericin; aqߙߙ=ߙaqueous phase, nbߙ=ߙnitrobenzene phase) were determined. Moreover, the stability constants of the 1·M2+ complexes in water-saturated nitrobenzene were calculated; they were found to increase in the cation series of Mg2+, Zn2+< Mn2+< Pb2+< Ba2+< Ca2+.
Synthesis of Colloidal InP/ZnS Nanocrystals for a Photosensitizer
Authors: Lee Seungyong , Reddy Vanga R. , Wu Jiang , Eyi Rick , Manasreh Omar 
Published: April 2012

ABSTRACTIts intrinsic nontoxicity makes the direct band gap InP/ZnS core/shell be one of the most promising semiconductor nanocrystals for optoelectric applications, with the advantage of tuning the optical absorption range in the desired solar spectrum region. Highly luminescent and monodisperse InP/ZnS nanocrystals were synthesized in a non-coordinating solvent under a thorough degassing process. By varying synthesis scheme, different size InP/ZnS nanocrystals were grown. For the purpose of ensuring air stability, ZnS shell was grown. This ZnS shell improves the chemical stability in terms of oxidation prevention. Measurements of absorption and emission were performed on different InP/ZnS nanocrystals with different sizes. As expected, the measurements show a red-shift as the size of the InP/ZnS nanocrystals increased.
First report on the importance of alien gobiids in the diet of native piscivorous fishes in the lower Vistula River (Poland)
Authors: Płąchocki Dariusz , Kobak Jarosław , Kakareko Tomasz 
Published: April 2012

Abstract
We conducted a snapshot study to check the importance of non-native Ponto-Caspian gobies (monkey and racer goby) in the diet of native obligate (northern pike, pikeperch) and facultative (Eurasian perch) predators in the Vistula River 3–4 years after the appearance of aliens. In total 71 fish with non-empty stomachs, taken randomly from net catches from various parts of the river were analyzed, including 32 pike, 20 pikeperch and 19 perch specimens. We found that gobiids prevailed in the diet of smaller (<30 cm standard length, SL) individuals of pike and pikeperch, as well as larger (>15 cm SL) specimens of perch, although the effect of predator size on the presence of gobiids in the diet was not significant in the case of perch. Our results indicate that gobiids as a prey fish can stimulate considerable changes in local food webs, which require further studies.
Dynamique des couples et thérapie dans les cas de cancer
Authors: Möhring Peter 
Published: April 2012

Résumé Dans ce travail, l’auteur présente un des cas de thérapie de couple où l’un des partenaires a souffert de cancer. Je montre comment la maladie s’insinue dans la dynamique psychique du couple et dans la structure de ses conflits inconscients. Une maladie qui menace la vie est un défi pour le lien de couple. Cela peut conduire à une relation plus étroite entre les partenaires, mais aussi susciter de la peur, de la rage et faire surgir les conflits latents. En conséquence, les besoins thérapeutiques peuvent être très différents et le thérapeute doit être très souple pour s’adapter aux besoins du couple, notamment selon les signes de stabilisation thérapeutique. L’auteur donne aussi quelques commentaires sur des aspects particuliers du contre-transfert. En préliminaire, il présente le lien d’amour inconscient comme la base de la relation de couple et ensuite cinq lignes directrices pour comprendre la dynamique des couples et l’insérer dans un registre psychanalytique. Il différencie : la transmission générationnelle, la distribution des rôles en famille, les modalités de lien, le niveau structurel et le point de vue de l’adaptation. Selon ces lignes directrices, il peut développer un schéma diagnostique qui me permet de comprendre des configurations psychodynamiques importantes et de décider quelle sorte de perspective thérapeutique peut être pratiquée, de conceptualiser l’évolution et les progrès dans le processus thérapeutique.
La haine de la descendance ou le fantasme de la bombe à retardement
Authors: Talpin Jean-Marc 
Published: April 2012

Résumé Diverses situations culturelles et cliniques nous confrontent au fantasme (ici appelé « fantasme de la bombe à retardement ») du vieillard ou du sujet en fin de vie de détruire post mortem sa famille soit en la privant d’héritage soit au contraire en effectuant des révélations traumatiques. Ce fantasme est exploré dans ses causes (narcissisme, emprise, angoisse de mort, haine vis-à-vis des survivants) et dans ses conséquences sur chacun et sur l’appareil psychique familial.
Le jeu en thérapie familiale psychanalytique
Authors: Granjon Evelyn 
Published: April 2012

Résumé Le jeu en famille est signe d’un bon fonctionnement de l’ Appareil Psychique Familial : ancré dans la culture, il est en rapport avec la « pensée familiale », aide à la construction de la temporalité et participe à la transmission psychique. Le jeu apparaît comme régulateur et organisateur de la vie psychique familiale. C’est une activité récréative et créative qui se joue dans les relations familiales et trouve sa source dans les liens familiaux. Les jeux en famille permettent que se raconte une histoire pour que se dise l’histoire : ils participent à la fonction mythopoïétique du groupe. Cependant, certaines familles semblent avoir perdu leurs possibilités de jouer ou en paraissent incapables. Tristesse, agir répétitifs et violence remplacent sourires et dires. La Thérapie Familiale Psychanalytique permet à ces familles, dans un espace groupal et grâce à un travail psychanalytique, de retrouver leurs capacités de représentation et leurs qualités ludiques, conditions nécessaires d’un bon fonctionnement psychique de chacun et de l’ensemble.
Travail du jeu et retissage d'un roman familial quand la filiation paternelle est désertée
Authors: Loncan Anne 
Published: April 2012

Résumé En se référant aux théories de la psychanalyse familiale, l’auteur présente la place que prend le jeu dans ce cadre, où il s’insère naturellement comme expérience de l’intersubjectivité. À travers l’exemple d’une famille monoparentale « amputée d’une lignée », sont présentés certains fragments décisifs pour l’élaboration psychique groupale. La construction du soi familial en sera favorisée, pour peu que le déni ait fait place à la reconnaissance de la douleur originaire liée à l’expérience esthétique, ici concomitante de la perte des origines du côté paternel.
Sacrifier les sacrifices de la guerre
Authors: Hauerwas Stanley , Chalamet Christophe 
Published: April 2012

Résumé Réfléchir sur les aspects moraux de la guerre a peu d’impact sur le déroulement concret d’une guerre, bien qu’il soit toujours important de travailler la notion de guerre juste. La guerre a fasciné notre imaginaire, si bien que pacifisme et non-violence posent mal le problème. Pour James, supprimer la guerre requiert que l’on préserve les vertus inhérentes à la guerre. Dans cet article, il s’agit plutôt de montrer la nécessité de sacrifier notre refus de tuer. Le malaise chrétien face à la guerre est, en réalité, d’ordre liturgique. En Amérique, le sacrifice de soi est une donnée centrale de la religion civile. Les chrétiens doivent se rappeler que le seul critère du vrai n’est pas ce pour quoi il vaut la peine de tuer, mais ce pour quoi il vaut la peine de mourir. Il n’y a pas de manière plus éthique de conduire une guerre. L’alternative chrétienne est liturgique et ecclésiale. Le Christ a « englouti » l’acte de tuer de sorte que nous puissions vivre à nouveau en paix. Nous ne sommes donc plus condamnés à tuer.
La notion néotestamentaire de diakonia
Authors: Nebel Mathias 
Published: April 2012

Résumé La notion néotestamentaire de diakonia a été mal interprétée, si bien qu’une relecture de cette notion à la lumière de l’avènement en Jésus Christ du règne du Messie attendu par Israël s’impose. Ajoutons que la diakonia a acquis une consistance théologique spécifique. Elle n’est pas le simple « service des tables » popularisé par la pratique pastorale. Selon Beyer, il s’agit d’un amour humble et diligent pour le prochain, spécialement le plus démuni. En Allemagne, l’Église a développé plusieurs institutions nouvelles sur la base de cette acception. La traduction de Collins crée une efflorescence de nouvelles significations (action salvifique, service eucharistique, serviteur souffrant, etc.). Plusieurs péricopes évangéliques sont à travailler : Mc 10, 41-45 ; Lc 22, 24-27 ; Jn 18, 33-37 et Mt 25. Diakonia ou diakonein désignent la mission du Christ en tant qu’il accomplit le service du Père. Il convient de reparcourir l’exercice du pouvoir en Israël tel que le rapporte l’Ancien Testament : le roi d’Israël est roi comme diakon . Le Jésus de Matthieu se situe évidemment dans la lignée davidique. Sa Passion représente une diaconie royale paradoxale. L’Église participe de la diaconie du Christ. Le texte du lavement des pieds en Jn 13 est, à cet égard, le texte de référence. C’est ici que se construit la synonymie entre diaconia et ministerium . Mt 25 fonde ce que nous appelons aujourd’hui l’option préférentielle pour les pauvres.
Les dirigeants des entreprises familiales en France, 1970-2010
Authors: Daumas Jean-Claude 
Published: April 2012

Résumé Le capitalisme familial a longtemps eu mauvaise réputation mais, depuis les années 1990, de nombreuses recherches ont abouti, dans tous les pays, à sa réhabilitation : non seulement les firmes familiales sont les plus nombreuses mais leurs performances sont supérieures à celles des entreprises managériales. L’objectif de cet article est de cerner la spécificité des dirigeants familiaux par rapport aux managers salariés en s’interrogeant sur l’influence de l’union structurelle de la famille et de l’entreprise sur leurs comportements dans deux domaines : l’exercice du pouvoir dans l’entreprise et le mode de gestion. L’article ne substitue pas un discours systématiquement laudateur fondé sur l’accumulation de success stories à l’image caricaturale de dirigeants familiaux globalement défaillants, mais vise à en comprendre la logique dans toute sa complexité. Il est centré sur les grandes entreprises pour une double raison : la documentation les concernant est plus abondante que pour les PME et leur importance a longtemps été sous-estimée.
Les petits patrons en France au 20e siècle ou les atouts du flou
Authors: Zalc Claire 
Published: April 2012

Résumé Les petits patrons ont pendant longtemps fait figure de parents pauvres de l’historien(ne) contemporanéiste. Il serait erroné d’en dire autant aujourd’hui : depuis trente ans, le vide historiographique a commencé d’être comblé. Cet article se présente comme un bilan des travaux qui ont contribué à renouveler l’histoire du petit patronat en France au 20 e siècle sous l’influence, notamment, des autres sciences sociales. Les connaissances accumulées abordent un certain nombre de questions : le rapport au politique et à l’État, la thématique des mobilités sociales ou encore le rôle des réseaux et insertions sociales dans le fonctionnement des petites entreprises. Mais l’ensemble des travaux se heurte à la même difficulté : l’hétérogénéité essentielle du monde des petits patrons. Quêtes d’unité et de reconnaissance, porosités des frontières, malléabilité des structures, le petit patronat se définit par son flou qui n’est pas sans présenter un certain nombre d’atouts.
A rare case of peripheral T-cell lymphoma in 1-year-old child
Authors: Kandakumar Vignesh , Ganesan Prasanth , Bajpai Peush , Rajendranath Rejiv , Tenali Sagar , Majhi Urmila , Sivaprakasam Ponni 
Published: April 2012

AbstractPeripheral T-cell lymphoma (PTCL) represents approximately 12% of lymphoid neoplasms. They are even rarer in children and represent only 1% of Non-Hodgkin′s lymphoma in this age group. We report a case of PTCL in a 1-year-old female child for its rarity.
A Mito-Style Structure at Chavín De Huántar: Dating and Implications
Authors: Contreras Daniel A. 
Published: April 2012

AbstractExcavations west of the monumental core at Chavín de Huántar, Peru in 2005 revealed a well-preserved plastered structure with a central circular hearth, in the style of the Mito Architectural Tradition. This find challenges standard definitions of both the Mito Tradition and Chavín itself. I discuss the material remains and associated radiocarbon dates from this feature, and use these new data to re-assess Chavín’s involvement in interregional networks and its relationship to earlier ceremonial centers in the Central Andean highlands.
Cultural Transformations of the Chanka Homeland (Andahuaylas, Peru) During the Late Intermediate Period (A.D. 1000–1400)
Authors: Bauer Brian S. , Kellett Lucas C. 
Published: April 2012

AbstractOne of the largest demographic shifts to occur in Andean prehistory took place during the Late Intermediate Period (A.D. 1000–1400). Across a large expanse of the central Andes a vast number of lower elevation settlements were abandoned and local populations were concentrated in newly constructed, defensibly positioned sites, located along high ridges. In this article we examine this dramatic settlement shift in relation to the Chanka ethnic group that occupied the Andahuaylas region (Department of Apurimac, Peru). The results indicate that the shift from valley to hilltop settlements in the Andahuaylas region occurred around A.D. 1000. We propose that the shift reflects an increased dependency on agro-pastoralism that resulted from a period of climate change. We also suggest that in this region of the Andes the shift was augmented by growing levels of political competition after the dissolution of the Wari Empire and that current models, which situate the Chanka as a uniquely powerful ethnic group at the time of the Inca expansion, need to be reexamined.