bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical modeling and simulation of water hammer phenomena using the MacCormack method
Authors: Toumi Abdelouaheb , Sekiou Fateh , Afoufou Fateh 
Published: May 2024

ABSTRACT

Water hammer refers to pressure fluctuations caused by changes in fluid speed in hydraulic systems. This research proposes a model using the MacCormack method to study and control water hammer, specifically focusing on managing valve closure to reduce shock wave pressure during transient flow. Numerical simulations compare linear and quadratic closure laws for both rapid and gradual valve closure, with the goal of identifying the optimal laws. The findings show that with faster closure times, the overpressure at the valve section decreases linearly in the second quarter of the return period (t4). The application of the quadratic law results in reduced pressures at the valve compared to the linear law, with a maximum pressure difference of 0.05 bar between the highest and lowest values. When searching for the optimal valve closure law to mitigate overpressure, it is found that the exponent ‘m’ falls within the range of 1.117–1.599. As the slow closing time increases gradually, the range of variation for ‘m’ decreases. Furthermore, in the case of underpressure prevention, the exponent ‘m’ ranges from 0.95 to 1.419, and the range of ‘m’ remains relatively constant with the increase in closing time.
MiR-625-5p Modulates the Metastasis and Proliferation of Gastric Cancer Cells by Governing the M6A Demethylase ALKBH5
Authors: Jiang Wenjun , Guo Xiaodi , Ma Shanbo , Chang Yuanhong , Li Ya 
Published: May 2024

Background:
Gastric cancer is a prevalent malignant tumor globally, with metastasis and
recurrence serving as primary contributors to the diminished survival rates observed in patients with
advanced stages of the disease. Despite numerous investigations into the pathogenesis of gastric
cancer, the significance of m6A demethylase ALKBH5 in the initiation and progression of the disease
has been established, yet its precise mechanism remains incompletely understood.

Methods:
Immunohistochemistry was utilized for the evaluation of ALKBH5 expression in gastric
cancer tissues, while RT-qPCR and WB were employed for the analysis of ALKBH5 expression in
cells. Additionally, the levels of m6A methylation in RNA were assessed using the EpiQuikTM m6A
methylation quantitative assay kit. The proliferative and metastatic potentials of gastric cancer cells
were assessed using the CCK-8 and Transwell cell assays, respectively. The binding site between
miR-625-5p and ALKBH5 was predicted through the TargetScan website, and the interaction was
confirmed using a dual luciferase reporter assay.

Results:
The research findings indicated a significant increase in m6A methylation levels in gastric
cancer cells, concomitant with a substantial decrease in ALKBH5 expression. ALKBH5 can inhibit
the proliferation and metastasis of gastric cancer cells. Additionally, the interaction between miR-
625-5p and the 3'-UTR of ALKBH5 mRNA, resulting in the suppression of ALKBH5 expression,
was validated.

Conclusions:
Through its specific interaction with ALKBH5, miR-625-5p modulates the proliferation
and metastatic potential of gastric cancer cells, bridging a previously unexplored link in the
pathogenesis of gastric cancer between miR-625-5p and ALKBH5. This finding suggests that miR-
625-5p could be a potential target for treating gastric cancer, with the goal of enhancing patient outcomes
and quality of life.
Polymeric Nanoparticles for Wound Healing
Authors: Koliqi Rozafa , Uskokovic Vuk , Breznica Salmani Pranvera , Daka Grapci Arlinda , Mahapatra Chinmaya 
Published: May 2024

Abstract:
Skin injury is one of the most prevalent lesions in humans, and many such wounds, including
deep burns and chronic skin wounds, are notoriously difficult to heal. It has been established
by medical practitioners that current wound therapies are not perfectly effective and are far from satisfactory.
Meanwhile, nanotechnologies have made it possible to develop pharmaceutical formulations
that can elevate the effectiveness of conventional pharmacotherapies to entirely new heights.
Most nanostructured biomaterials used to treat wounds, including those that have helped establish
this fascinating subject, have been polymeric. The bibliographic analysis presented here shows a
steady growth in the research output of studies on the use of polymeric nanoparticles in wound healing
therapies. This article provides an overview of polymeric nanoparticles for the treatment of
wounds with an emphasis on different chemistries and polymer-drug combinations that have been
proven the most effective. The wound age, pathophysiology, wound healing treatments of the present
and past, as well as the physicochemical nature and methods for the synthesis of polymeric nanoparticles,
are all covered in the opening parts of the review. The existing polymeric nano-drug delivery
systems with the greatest promise for wound healing and skin regeneration are subsequently
addressed and their potentials summarized.
Social challenge stressors and work engagement: the moderating role of political skill
Authors: De Moraes Romulo Matos , Miranda Valtair Afonso , Istoe Rosalee Santos Crespo 
Published: May 2024

This study offers a counterpoint to the generalization of positive and linear effects resulting from challenge stressors in the workplace. The guiding objective was to verify whether social challenge stress impacts individuals' work engagement positively or negatively, according to the political skill degree available by professionals. We used moderation analysis and hierarchical regression to assess these relationships. The sample comes from civil servants of a Brazilian federal institution (N = 606). The results indicate that political skill moderates the relationship between social stress and engagement positively, except in cases where such skill is low, a situation in which the interaction becomes negative. The evidence also reveals that a positive curvilinear association better explains the association between social stress and work engagement. The findings suggest that the Challenge-Hindrance Stress Framework (CHF) has an application conditioned by the possible abilities that a given stressor demands to be evaluated as an obstacle or a challenge. We intended to extend the theory on stressors and contribute to the human resource management practice by elucidating conditions or portions of professionals in which the CHF does not apply or lacks contextualization.
A potential vorticity diagnostics package for MPAS-Atmosphere
Authors: Chasteen Manda B , Wong May W S , Szapiro Nicholas 
Published: May 2024

Ertel’s potential vorticity (PV) is an important quantity in atmospheric
dynamics that succinctly encompasses the principles of mass, momentum,
and energy conservation and is applicable to all scales of motion. In
this paper, we describe the implementation of a PV diagnostics package
into the atmospheric component of the Model for Prediction Across Scales
(MPAS), a fully compressible nonhydrostatic global model that enables
regional mesh refinement to convection-permitting resolutions and is
highly suited for studies on multiscale process interactions and
forecast error-growth dynamics.
The version of the PV diagnostics package emphasized herein will be
included in an upcoming MPAS release and significantly improves upon an
original version that was introduced in MPAS v5.0. Specifically, this
revised version enables the calculation of the full Eulerian PV budget
at each time step Δt (i.e., the instantaneous budget) and the
accumulation of PV tendencies throughout the model integration (i.e.,
the accumulated budget). Through the formulation of the discretized PV
budget equation and global simulations conducted on a 15–3-km
variable-resolution mesh, we demonstrate that the instantaneous PV
budget closes down to machine roundoff in both single- and
double-precisions. Further, we find that the PV budget computed using
accumulated PV tendencies leads to a small source of residual that
arises due to the inherent nonlinearity of PV, which leads to leads to
mathematical inconsistencies between the discretized equation for
calculating the PV budget over any arbitrary period longer than Δt and
that which results from accumulating the PV tendencies themselves over
successive time steps.
Pengaruh Kombinasi Populasi Tumpangsari Kedelai-Singkong pada Pertumbuhan dan Hasil Benih Tanaman Kedelai dan Hasil Umbi Singkong
Authors: Pramono Eko , Manik Tumiar Katarina B. , Hadi Muhammad Syamsoel , Salsabila Erika Fadia 
Published: May 2024

Intercropping soybeans with cassava can become one solution to increase the production of soybean in Indonesia. This research aimed to determine the most optimal population combination of soybean-cassava intercropping for the growth and yield of soybean seeds, cassava tuber yield, and land use efficiency (LUE).. The research was carried out on the farm land of the Main Seed Center in Sekincau District, West Lampung Regency, Lampung Province, Indonesia at -5°02’27” South and 104°18’16” East at elevation of 1173.1 meter from sea level and at the Seed and Plant Breeding Laboratory Faculty of Agriculture University of Lampung during June 2022 - February 2023. The four treatments of population combination of soybean-cassava intercropping were applied in a completely randomized block design (CRBD) and replicated five times in five blocks. The four population combination treatments of soybean-cassava intercropping were a) 100% soybean and 0% cassava (monoculture) (p₁), b) 67% soybean and 97% cassava (p₂), c) 67% soybean and 89% cassava (p₃), and d) 50% soybeans and 97% cassava (p₄). The growth and the seed yield per soybean stem of monoculture did not differ to those of the soybean-cassava intercropping, but the soybean seed yield per plot area of the intercropping was lower than those of monoculture. Its mainly due to the soybean population of the intercropping was lower compared to monoculture. All population combinations in soybean-cassava intercropping were effective in supporting the growth and yield of soybean seeds, but the population combination of 50% soybean and 97% cassava (p₄) was also effective in supporting cassava tuber yield, and had the highest land use efficiency among other population combinations. Key words: flowering age, plant height, seed weight, tuber weight of cassava
Implementation of Village Fund Allocation Policy to Realize Village Self-Reliance
Authors: Reginaldis Maria M , Supriyono Bambang , Setyowati Endah , Amin Fadilah 
Published: May 2024

Introduction: The welfare of rural communities in developing countries such as Indonesia is a significant concern for the government. Therefore, the government's implementation of policies related to village fund allocation is expected to enhance the welfare of village communities. However, in practice, this policy has not yet brought about significant changes in the local communities, particularly in achieving village self-reliance.

Literature review: Policy implementation from the Triangle Model perspective is an approach developed by Walt & Gilson, (1994) which emphasizes four main stages in the policy process, namely agenda setting, formulation, implementation and evaluation. The agenda setting stage involves the selection of various problems faced by society to become the focus of decision makers. Next, in the formulation stage, legislative and decision-making bodies design and ratify policies. The implementation process is carried out by the government, followed by an evaluation stage that assesses the impact of the policy.

Method: This article aims to examine the process of implementing village fund allocation policies using the triangle analysis model (Buse et al., 2005) .The research informants comprised 23 individuals.

Result and Discussion: The results of this study indicate that the objectives of implementing village fund allocation in the Semangga district are known to the implementers/actors, as well as the benefits of village fund allocation being perceived by the village communities. However, the policy implementers lack effective communication to convince and educate the village communities. Additionally, there is a need to enhance human resource commitment and allocate additional funds to advance the villages towards self-reliance.

Conclusion: The findings of this study specifically demonstrate the real conditions in the research location regarding village fund allocation. This article presents opportunities for further research using the triangle analysis model in the implementation of village fund allocation policies.
Promoting Sustainability in Manufacturing Companies in Coahuila, Mexico: Integrating Sustainable Practices Into Organizational Culture
Authors: Morejón Victor Manuel Molina , Cano Lucila Zárraga , Sandoval Enrique Corona 
Published: May 2024

Objective: The objective is to obtain the validity of the relationships between the four factors of Denison's model: involvement, consistency, adaptability, and mission, and their impact on sustainability.

Theoretical Framework: This article explores the competitive role of organizational culture in sustainability in the northern state of Mexico, characterized by manufacturing processes in which waste, energy, and water manifested as significant components of the region and the country.

Method: The data were collected with the application of the standardized questionnaire called Denison Organizational Culture Survey and its impact on the sustainability indicators of the Global Reporting Initiative, applying a structural equation model based on SmartPLS 4. 0.

Research Implications: The best results obtained in companies where external focus prevails, with stability and flexibility, that is, with an organizational culture where mission and adaptability are pillars.

Originality/Value: The conclusions highlight contributions to the academic and business environment, applying a model that makes visible aspects challenging to assimilate in management due to the intangibility of the organizational culture.
Meta Analysis of The Relationship Between Corporate Social Responsibility and Tax Aggressiveness
Authors: Widuri Retnaningtyas , Subroto Bambang , Saraswati Erwin , Rusydi Mohamad Khoiru 
Published: May 2024

Objective: The objective of this study is to investigate the relationship between corporate social responsibility and tax aggressiveness, with the aim of looking at the firmness of the relationship.

Theoretical Framework: This study aims to examine the strength and reliability of the connection between corporate social responsibility (CSR) and aggressive tax dodging actions through the utilization of a meta-analysis methodology.

Method: The quantitative method used is a meta-analysis approach of 61 studies and 228 observations.

Results and Discussion: The results of this study found a firm relationship between corporate social responsibility and tax aggressiveness. Through a meta-analysis, the results of the negative relationship between CSR and tax agressiveness were obtained. The next result was to confirm that the heterogeneity of previous research results related to CSR, and tax agresiveness was due to the diversity of CSR measurement strategies and characteristics of the state legal system.

Research Implications: This research has provided input into the fields of accounting and taxation by giving confidence in the relationship between aggressive tax behavior and the existence of disclosures of social responsibility

Originality/Value: This research is one of several studies using a meta-analysis approach. Different from other topics raised using this approach, in this research, the emphasis of the study is on the disclosure of CSR, which is correlated with the degree of the tendency of aggressive tax behavior or activities. The study also uses moderators that have not been used in previous meta-analysis studies, namely state law characteristics.
اختيارات ابن القَرَّاب النحوية في اسناد الفعل الى الضمائر
Authors: صالح عبد محمود , طـه حـســن عـلـي 
Published: May 2024

قد تطلب عملنا في هذا البحث والذي وسمناه بـ(اختيارات ابن القَرَّاب النحوية في اسناد الأفعال الى الضمائر), أن يتضمن مقدمة ذكرت فيها اسم البحث والمنهج الذي سرت عليه فيه فقد كان منهج البحث قائما على ذكر المسألة، وبعدها الآية القرآنية التي تخص المسألة المذكورة، وتخريج القراءة من كتب القراءات، ومن ثم حجة كل قراءة، على أن تقدَّم القراءة غير المختارة، والتأصيل الصرفي للمسألة، ومن ثم التنظير لها، وعند الانتهاء من عرض وتحليل المسألة أقدِّم رأياً لي أحياناً, وقد قسَّمته على مباحث ثلاثة, الاول: اسناد الفعل الى المتكلم, والثاني: اسناد الفعل الى المخاطب, والثالث: اسناد الفعل الى الغائب, ومن ثم خاتمة تضمنت النتائج التي توصلنا اليها من خلال هذا البحث, والمصادر التي اعتمدناها فيه.
انتخابات عام 1994 وتولي أنجيلا ميركل منصب وزارة البيئة
Authors: عبد صالح مروج هادي , عبد الرحمن حارث 
Published: May 2024

في الانتخابات العامة لعام 1994 في ألمانيا، فازت الحزب الديمقراطي الاجتماعي (SPD) بزعامة هلموت كول (Helmut Kohl) بأغلبية الأصوات. وقد شكل حكومة تعاونية مع الحزب الاشتراكي الديمقراطي (FDP). تميّزت هذه الانتخابات بأهمية كونها ساهمت في تحديد السياسة الداخلية والخارجية لألمانيا في الفترة التي تلت انتهاء الحرب الباردة.
في العام نفسه، تم تعيين أنجيلا ميركل وزيرة للبيئة وحماية الطبيعة وسلامة الرياضة في حكومة مقاطعة سكسونيا السفلى. كانت هذه الخطوة أولى خطواتها نحو توليها المناصب الحكومية العليا في ألمانيا. وقد قادت ميركل جهوداً حثيثة للحفاظ على البيئة وتعزيز الاستدامة، وذلك من خلال التركيز على قضايا مثل الحفاظ على الموارد الطبيعية ومكافحة التلوث.
تولت ميركل منصب وزيرة البيئة في ظل أزمة البيئة التي كانت تشهدها أوروبا، حيث كانت هناك مخاوف متزايدة بشأن تغير المناخ وتلوث الهواء والمياه. قادت ميركل جهوداً لوضع استراتيجية واضحة لحماية البيئة وتعزيز الوعي بقضايا البيئة، مما جعلها شخصية بارزة في المجال البيئي.
بالإضافة إلى دورها في الحكومة المحلية، استمرت أنجيلا ميركل في تطوير مسيرتها السياسية وأصبحت فيما بعد أول امرأة تشغل منصب مستشارة لألمانيا. تميزت فترة حكم ميركل بالتحديات الدولية والداخلية، واتخذت قرارات هامة في مختلف المجالات، مما جعلها واحدة من الشخصيات السياسية البارزة عالمياً.
أثر تصميم تعليمي وفق انماط التعلم لأنموذج (felder & solman) في التفكير الحاذق لدى طلبة المرحلة الثانوية في مادة الرياضيات
Authors: مضحي ندى شحاذه 
Published: May 2024

هدف البحث التعرف الى أثر تصميم تعليمي وفق انماط التعلم لأنموذج (felder & solman) في التفكير الحاذق لدى طلبة المرحلة الثانوية في مادة الرياضيات, ولتحقيق هدف اعتـمدت الباحثة التصميم التجريبي ذي الاختبار البعدي للمجموعتين متكافئتين ,لقد تم مكافئة بـ(المعرفة السابقة, الذكاء, والتحصيل السابق ) ,وتكونت العينة من (67) طالبة بواقع (35)طالبة للمجموعة التجريبية و(32) طالبة للمجموعة الضابطة, وتـم اعداد اختبار للتفكير الحاذق لطــالبات الصف الرابع العلمي المكون من (35) فقرة ,وتم استخراج الصدق والثبات وكانت جيدة وتم استخدام الوسائل الاحصائية المناسبة.
Aromaterapia como prática não farmacológica para manejo da dor em crianças
Authors: Chammaa Aya , Zilly Adriana , Luz Larissa Djanilda Parra da , Tibes-Cherman Chris Mayara 
Published: May 2024

Objetivo: analisar estudos realizados sobre o uso de aromaterapia como prática não farmacológica para manejo da dor em crianças. Métodos: trata-se de uma revisão integrativa acerca do assunto relacionado ao uso da aromaterapia no setor pediátrico. Foram realizadas buscas nos periódicos SciELO, PubMed e Medline de artigos publicados entre o ano de 2013 e 2023. Resultados: a partir da pesquisa nas bases de dados estabelecidas, foram identificados 395 estudos. Os títulos e resumos dos mesmos foram lidos, seguindo os critérios de inclusão e exclusão, resultando na exclusão de 342 artigos que não abordaram a aromaterapia na pediatria na primeira análise. Na segunda análise, procedeu-se à exclusão de outros nove artigos, resultando em nove artigos incluídos na pesquisa. Considerações Finais: a aromaterapia, especialmente com óleo de lavanda, pode ser uma opção promissora e complementar no manejo da dor e no aumento do bem-estar em diversos cenários clínicos, embora seja importante considerar a individualidade de cada paciente e contexto ao aplicar essa abordagem terapêutica.
Enfrentamento ao ageísmo por meio das relações intergeracionais frente à transição demográfica
Authors: Lopes Clara Sobreira Dias , Gonçalves Emanuelle Cristina Soares , Oliveira Lorena Amaral de , Fernandes Maria Teresinha de Oliveira , Horta Natália de Cássia , Souza Marina Celly Martins Ribeiro de 
Published: May 2024

Objetivo: Identificar ferramentas de enfrentamento ao ageísmo desenvolvidas por meio das relações intergeracionais frente à transição demográfica. Métodos: Trata-se de revisão integrativa em que foram selecionados 21 artigos na Web of science, Pubmed, Embase, Portal Capes e Scopus. Resultados: Observou-se que quanto maior o contato com a população idosa e mais conhecimento sobre o envelhecimento, seja no meio educacional, familiar, ou dos profissionais cuidadores, menos estereótipos negativos são vistos em relação às pessoas mais velhas. A promoção de relações intergeracionais no ambiente familiar e no mercado de trabalho foi outra importante ferramenta no combate ao idadismo, especialmente no contexto da pandemia da COVID-19. Os efeitos positivos da autopercepção do envelhecimento foram observados em pessoas que vivem em regiões com envelhecimento populacional lento. Considerações finais: Quanto maior o conhecimento sobre o processo de envelhecimento e contato com pessoas idosas, mais atitudes e visões positivas em relação a esse grupo foram agregadas enquanto ferramentas de enfrentamento ao idadismo em vários espaços sociais. Como limitação do estudo, destaca-se a escassez de publicações sobre as relações intergeracionais e seu impacto na redução do ageísmo após a pandemia da COVID-19.
Culto da Razão como Fundamento da República" de Alain (Émile Chartier)
Authors: Lacour Philippe , Oliveira Chaia Jade , Mendes Sbervelheri Mariana , Alves Teixeira Michelly , Santos dos Prazeres Rogério 
Published: May 2024

O texto aqui traduzido foi publicado originalmente na Revue de Métaphysique et de Morale, em janeiro de 1901. Trata-se de uma crônica de Alain, pseudônimo utilizado por Émile Chartier, no qual busca afirmar que a Razão seria o instrumento mais eficaz de uma dada ordem social. A Razão seria, portanto, o verdadeiro Deus e seria justo dizer que se deve um Culto à ela. A tradução foi realizada pelo do Grupo de Tradução do Departamento de Filosofia da Universidade de Brasília, coordenado pelo Professor Philippe Lacour. O grupo se propõe a traduzir regularmente obras de filosofia ainda inéditas em língua portuguesa e disponibilizá-las em periódicos de acesso livre. O trabalho de tradução é produzido de maneira colaborativa através da plataforma digital TraduXio (https://traduxio.org/).