bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Efficient and Selective Synthesis of Alkoxy‐Substituted Di(pyridin‐2‐yl)amines and N‐Arylpyridin‐2‐ylamines.
Authors: Grig‐Alexa Irina‐Claudia , Simionescu Iuliana , Patriciu Oana , Massip Stephane , Finaru Adriana‐Luminita , Jarry Christian , Leger Jean‐Michel , Guillaumet Gerald 
Published: July 2012

AbstractUnexpected products (IV) and (VII) are formed during the reduction of the nitro group of substrates (I) in different alcohols.
ChemInform Abstract: FeF3 as a Novel Catalyst for the Synthesis of Polyhydroquinoline Derivatives via Unsymmetrical Hantzsch Reaction.
Authors: Surasani Rajendra , Kalita Dipak , Rao A. V. Dhanunjaya , Yarbagi Kaviraj , Chandrasekhar K. B. 
Published: July 2012

AbstractFour‐component condensation of β‐keto compounds (I), aromatic aldehydes (II), acetoacetate (III) and ammonium acetate in the presence of iron trifluoride affords the polyhydroquinolines (IV) in high yields and short reaction time.
ChemInform Abstract: Revisit to the Biginelli Reaction: A Novel and Recyclable Bioglycerol‐Based Sulfonic Acid Functionalized Carbon Catalyst for One‐Pot Synthesis of Substituted 3,4‐Dihydropyrimidin‐2‐(1H)‐ones.
Authors: Konkala Karnakar , Sabbavarapu Narayana Murthy , Katla Ramesh , Durga Nageswar Yadavalli Venkata , Reddy T Vijai Kumar , Devi Bethala L. A. Prabhavathi , Prasad Rachapudi B. N. 
Published: July 2012

Abstractthe catalyst material is prepared by in situ partial carbonization and sulfonylation from biobased glycerol (biodiesel by‐product or waste from fat splitting) and successfully applied to the Biginelli reaction.
ChemInform Abstract: Efficient One‐Pot Synthesis of Cyclic β‐Enaminoamides by Thermal Wolff Rearrangement of Cyclic 2‐Diazo‐1,3‐dicarbonyls and Conversion to Uracil Derivatives.
Authors: Neupane Pratik , Li Xin , Jung Jae Hak , Lee Yong Rok , Kim Sung Hong 
Published: July 2012

AbstractThe presented simple synthesis of the title compounds starts from the readily available cyclic diazodicarbonyls (I), (VI), and (IX).
ChemInform Abstract: Highly Enantioselective Synthesis of 2,3‐Dihydroquinazolinones Through Intramolecular Amidation of Imines.
Authors: Prakash Muthuraj , Kesavan Venkitasamy 
Published: July 2012

AbstractA Sc‐catalyzed tandem imination/intramolecular amidation of anthranilamide with different aldehydes can be achieved with good to excellent enantioselectivity in the presence of an inda‐pybox catalyst.
ChemInform Abstract: Transition‐Metal‐Free Intramolecular N‐Arylations.
Authors: Thome Isabelle , Bolm Carsten 
Published: July 2012

AbstractPhenoxazines and related pyrido analogues are prepared by metal‐free base promoted cyclization of N‐acetylated (2‐iodoaryloxy) anilides of type (I) and (III).
ChemInform Abstract: Microwave Assisted Synthesis of 3‐Benzazepine‐2‐ones as Building Blocks for 2,3‐Disubstituted Tetrahydro‐3‐benzazepines.
Authors: Sarkar Soumya , Husain Syed Masood , Schepmann Dirk , Froehlich Roland , Wuensch Bernhard 
Published: July 2012

AbstractThe compounds (VI) are investigated for their affinities toward σ1 and σ2 receptors in competitive receptor binding studies.
ChemInform Abstract: Cascade Intermolecular Michael Addition—Intramolecular Azide/Internal Alkyne 1,3‐Dipolar Cycloaddition Reaction in One Pot.
Authors: Arigela Rajesh K. , Mandadapu Anil K. , Sharma Sudhir K. , Kumar Brijesh , Kundu Bijoy 
Published: July 2012

AbstractThe simple and efficient synthesis of the highly complex N‐heterocyclic system proceeds via Michael addition of 2‐alkynylindoles with nitroalkenes and subsequent intramolecular azide/alkyne 1,3‐dipolar cycloaddition.
ChemInform Abstract: Unexpected Copper(II) Catalysis: Catalytic Amine Base Promoted β‐Borylation of α,β‐Unsaturated Carbonyl Compounds in Water.
Authors: Thorpe Steven B. , Calderone Joseph A. , Santos Webster L. 
Published: July 2012

AbstractUnexpectedly simple conditions are developed which render possible the β‐borylation of a variety of α,β‐unsaturated carbonyl compounds.
ChemInform Abstract: Synthesis of CF3‐Containing α‐Alkynyl‐α‐aminophosphonates by Sonogashira Cross‐Coupling Reaction.
Authors: Zotova Maria A. , Vasilyeva Tamara P. , Peregudov Alexander S. , Osipov Sergey N. 
Published: July 2012

Abstractα‐CF3‐α‐Aminophosphonate derivatives (III) and (VI) comprising an arylalkynyl moiety at the α‐carbon atom are prepared via palladium‐catalyzed cross‐coupling of the corresponding terminal alkynes (I) and (V) with aryl iodides (II).
ChemInform Abstract: A Facile Synthesis of Aminomethylene Bisphosphonates Catalyzed by Ytterbium Perfluorooctanoate under Ionic Liquid Condition.
Authors: Reddy Mudumala Veera Narayana , Kim Jongsik , Jeong Yeon Tae 
Published: July 2012

AbstractAn environmentally benign and practically feasible method for the synthesis of aminomethylene bisphosphonates (IV) is developed.
ChemInform Abstract: Efficient Synthesis of Succinate Derivatives Using Mercaptoalkanols or Mercaptophenols.
Authors: Hajinasiri Rahimeh , Hossaini Zinatossadat , Rostami‐Charati Faramarz , Mirzaie Roghaye , Ahmadpoor Sara 
Published: July 2012

AbstractThe one‐pot synthesis of diastereomeric dialkyl 2‐(diphenoxyphosphoryl)‐3‐sulfanylsuccinate derivatives (IV) and (V) is reported and a plausible reaction mechanism is outlined.
ChemInform Abstract: Base‐Mediated Tandem Reaction of α‐Aryloxyacetophenones with Phosphonates: Selective Synthesis of Enol Phosphates.
Authors: Song Ren‐Jie , Liu Yan‐Yun , Wu Ji‐Cheng , Xie Ye‐Xiang , Deng Guo‐Bo , Yang Xu‐Heng , Liu Yu , Li Jin‐Heng 
Published: July 2012

AbstractA novel, simple method is developed for the synthesis of enol phosphates.
ChemInform Abstract: Exploration of α‐Aminophosphonate N‐Derivatives as Novel, Potent and Selective Inhibitors of Protein Tyrosine Phosphatases.
Authors: Wang Qingming , Zhu Miaoli , Zhu Ruiting , Lu Liping , Yuan Caixia , Xing Shu , Fu Xueqi , Mei Yuhua , Hang Qingwei 
Published: July 2012

AbstractDifferent synthetic strategies are used for the synthesis of various α‐aminophosphonates.
ChemInform Abstract: Preparation of Functional Phosphorus Zwitterions from Activated Alkanes, Aldehydes, and Tributylphosphine: Synthesis of Polysubstituted Furo[3,2‐c]coumarins.
Authors: Lee Chia‐Jui , Jang Yeong‐Jiunn , Wu Zong‐Ze , Lin Wenwei 
Published: July 2012

AbstractA general procedure allows the synthesis of new types of highly functionalized title compounds.
ChemInform Abstract: Advanced Preparation of Functionalized Triarylbismuths and Triheteroaryl‐Bismuths: New Scope and Alternatives.
Authors: Urgin Karene , Aube Christophe , Pichon Christophe , Pipelier Muriel , Blot Virginie , Thobie‐Gautier Christine , Leonel Eric , Dubreuil Didier , Condon Sylvie 
Published: July 2012

AbstractNovel methods are developed for the preparation of the synthetically important bismuth agents.
ChemInform Abstract: Synthesis of Thioglycosides from Propargyl Glycosides Exploiting Alkynophilic Gold Catalyst.
Authors: Vidadala Srinivasa Rao , Thadke Shivaji A. , Hotha Srinivas , Kashyap Sudhir 
Published: July 2012

AbstractA mild method for the preparation of thioglycosides (14 examples) is presented.
ChemInform Abstract: Cytotoxic Xanthone Glycosides from Aerial Part of Centaurium spicatum.
Authors: Allam Ahmed E. , El‐Shanawany Mohamed A. , Backheet Enaam Y. , Nafady Alaa M. , Takano Fumihide , Ohta Tomihisa 
Published: July 2012

AbstractNew xanthone glycoside (I) and two known xanthones are isolated from title plant.
ChemInform Abstract: Identification and Evaluation of Apoptotic Compounds from Garcinia oligantha.
Authors: Gao Xue‐Mei , Yu Ting , Cui Ming‐zhu , Pu Jian‐Xin , Du Xue , Han Quan‐bin , Hu Qiu‐fen , Liu Tian‐Cheng , Luo Kathy Qian , Xu Hong‐Xi 
Published: July 2012

AbstractOliganthins A (I), B (II), C (III) and D (IV) as well as the known gaudichaudione H are isolated from the stems of the title species.
ChemInform Abstract: Biologically Active Secondary Metabolites from Fungi. Part 51. Phomopsinones A—D: Four New Pyrenocines from Endophytic Fungus Phomopsis sp.
Authors: Hussain Hidayat , Krohn Karsten , Ahmed Ishtiaq , Draeger Siegfried , Schulz Barbara , Di Pietro Sebastiano , Pescitelli Gennaro 
Published: July 2012

Abstractisolation, structure elucidation and antifungal activity of phomopsinones A (I), B (IIa), C (IIc), and D (III)
ChemInform Abstract: Site‐Directed Spin Labelling of Nucleic Acids
Authors: Shelke Sandip A. , Sigurdsson Snorri Th. 
Published: July 2012

AbstractReview: covalent labelling by post‐synthetic spin labelling or during oligonucleotide synthesis and non‐covalent labelling by mixing the spin label with the nucleid acid immediately prior to the EPR measurement; ca. 150 refs.
ChemInform Abstract: The Chemistry of Localized Singlet 1,3‐Diradicals (Biradicals): From Putative Intermedates to Persistent Species and Unusual Molecules with a π‐Single Bonded Character
Authors: Abe Manabu , Ye Jianhuai , Mishima Megumi 
Published: July 2012

AbstractReview: about 100 refs.
Kinetic Considerations on Thermophilic Digestion of Maize Silage at Different Feeding Modes
Authors: Golkowska Katarzyna , Sibisi‐Beierlein Nonjabulo , Greger Manfred 
Published: July 2012

AbstractDigestion of maize silage in batch, semi‐batch and continuous mode was investigated under similar experimental conditions with the aim to compare the degradation kinetics. The modeling with the 1st order equation shows that despite the ensiling pre‐treatment the disintegration/hydrolysis step determines the total degradation rate of the substrate. The results confirmed an extremely high adaptation capability of anaerobic biocenosis to increased feeding frequency, rather than to higher but less frequent loadings. 2 – 3 times higher degradation rates were observed for tripled feeding frequency. On the other hand, an increase in organic loading within the same feeding mode always resulted in reduction of digestion rate.
Fixed bed and reduced lumped diffusion model parameter estimation of copper biosorption using Aspergillus niger biomass
Authors: Mukhopadhyay Mausumi , Kaur Tejinder , Khanna Richa 
Published: July 2012

AbstractIn this study, fixed bed model and reduced lumped diffusion model were used to explain biosorption behaviour of Cu (II) in a continuous column of Aspergillus niger biomass. The breakthrough time was evaluated for both models as a function of influent flow rate and bed height for a feed solution at 10 mg/L metal ion concentration and compared with experimental results. MATLAB was used to solve the partial differential equations and breakthrough curve was plotted. The breakthrough time obtained experimentally was comparable with data evaluated by these models. It was observed that fixed bed model and reduced lumped diffusion model can predict column dynamics more accurately at high flow rate, that is, at 9.8 mL/min for all (2.1, 3.1, and 4.1 cm) bed heights. © 2011 Canadian Society for Chemical Engineering
A generic method for measuring the potential number of structure‐preserving transformations
Authors: Neuman Yair , Cohen Yohai , Bekerman Zvi , Nave Ophir 
Published: July 2012

AbstractIn many fields of psychology, it may be interesting to measure the potential number of structure‐preserving transformations that exist between succeeding structures. The aim of this article is to present a methodology for measuring the potential number of structure‐preserving transformations between succeeding structures and to illustrate the applicability of the methodology through a case study. The article concludes by discussing the lessons and implications of the proposed methodology for microgenetic research. © Wiley Periodicals, Inc. Complexity, 2012
Control of the phase composition and morphology of a Cu‐Sb eutectic alloy via liquid‐liquid structure transition
Authors: Huang Zhong‐Yue , Zu Fang‐Qiu , Li Xiao‐Yun 
Published: July 2012

AbstractThe current paper focuses on the solidification characteristics of a Cu‐Sb eutectic alloy in its different liquid states. Liquid alloy resistivity‐temperature patterns suggest an irreversible temperature‐induced liquid‐liquid structure transition (TI‐LLST), and a reversible TI‐LLST occurred during the heating‐cooling runs. A set of solidification experiments was conducted based on the results. The irreversible TI‐LLST caused an enhanced solidification undercooling, increased solidification rate, refined regular eutectic morphologies, and absence of a pre‐eutectic Cu2Sb phase. The reversible TI‐LLST resulted in different phase compositions and eutectic structures. The mechanisms behind these transitions are also briefly discussed.
Capsule‐like α‐Fe2O3 nanoparticles: Synthesis, characterization, and growth mechanism
Authors: Su Changhua , Wang Hui 
Published: July 2012

AbstractUniform capsule‐like α‐Fe2O3 particles were synthesized via a simple hydrothermal method, employing FeCl3 and CH3COONa as the precursors and sodium dodecyl sulfate (SDS) as soft template. X‐ray powder diffraction (XRD), field emission scanning electron microscopy (FE‐SEM), transmission electron microscopy (TEM), and high‐resolution transmission electron microscopy were used to characterize the structure of synthesized products. Some factors influencing the formation of capsule‐like α‐Fe2O3 particles were systematically investigated, including different kinds of surfactants, the concentration of SDS, and reaction times. The investigation on the evolution formation reveals that SDS was critical to control the morphology of final products, and a possible five‐step growth mechanism was presented by tracking the structures of the products at different reaction stages.
Brittleness of protein crystals
Authors: Nanev C. N. 
Published: July 2012

AbstractA simple technique for studying the brittleness of small crystals is reported. The limits of fracture toughness of tetragonal hen‐egg white lysozyme crystals, oriented with their c‐axis normally to the substrate, were measured. The strong mechanics anisotropy of those crystals was confirmed. The role of the water present in the protein crystal lattice was re‐considered in seek for a more holistic understanding of the process, the idea being that the intra‐crystalline solution sustains the globular protein molecules in their native configuration. Also it is argued that this water may contribute for holding together the huge bio‐molecules in the crystal lattice (that is to act as additional “glue” in the crystal). The hypothesis is that dynamic chains of H‐bonds in the intra‐crystalline water are likely to be prolonged to connect protein‐to‐water‐to‐protein.
Online analytical investigations on solvent‐, temperature‐ and water vapour‐induced phase transformations of citric acid
Authors: Helmdach L. , Feth M. P. , Ulrich J. 
Published: July 2012

AbstractIt was demonstrated exemplarily for the crystallization of citric acid that the usage of an ultrasound device as well as Raman spectroscopy enables the inline measurement and the control of phase transitions. The influence of different solvent compositions (water and ethanol‐water) on the crystallization of citric acid was investigated. By increasing the ethanol content the transformation point was shifted towards higher temperatures. In addition, a strong impact on the nucleation point as well as on the crystal habit was detected in ethanol‐water mixtures. The results lead to the assumption that a citric acid solvate exists, which is, however, highly unstable upon isolation from mother liquor and converts fast into the known anhydrate or monohydrate forms of citric acid. The presence of such a solvate, however, could not be proven during this study. Furthermore, factors such as temperature and humidity which might influence the phase transition of the solid product were analyzed by Hotstage‐Raman Spectroscopy and Water Vapor Sorption Gravimetry‐Dispersive Raman Spectroscopy. Both, tempereature as well as humidity show a strong influence on the behaviour of CAM.
How much can the orientation of G's eigenvectors tell us about genetic constraints?
Authors: Berner Daniel 
Published: July 2012

AbstractA key goal in evolutionary quantitative genetics is to understand how evolutionary trajectories are constrained by pleiotropic coupling among multiple traits. Because studying pleiotropic constraints directly at the molecular genetic level remains very difficult, several analytical approaches attempt to draw conclusions about constraints by relating the orientation of the eigenvectors of the traits' (co)variance matrix to vectors of multivariate selection. On the basis of explicit models of genetic architecture, I here argue that the value of such approaches is greatly overestimated. The reason is that eigenvector orientation can be highly unstable and lack a biologically meaningful relationship with the underlying traits' genetic architecture. Genetic constraints are more profitably explored through experimental approaches avoiding the mathematical abstraction inherent in eigenanalysis.
Subsequent Chemical Reactions of Photochromic 4,5‐Dibenzothienylthiazoles
Authors: Nakagawa Hisako , Nakashima Takuya , Kawai Tsuyoshi 
Published: July 2012

Abstract4,5‐Dibenzothienylthiazole derivatives having leaving groups at the reactive 2‐positions of benzothiophene rings have been synthesized, and their photochromic ring‐closing reaction followed by spontaneous elimination and substitution reactions have been studied. A 4,5‐dibenzothienylthiazole having an ethoxy group and a hydrogen atom at each 2‐position of the benzothienyl ring underwent elimination to generate a condensed aromatic structure upon the addition of acid. 4,5‐Dibenzothienylthiazoles having an ethoxy or methyl groups at the 2‐position of the benzothienyl rings showed photochromism both in hexane and in methanol solutions with photocyclization quantum yields as high as 60 %. Upon the addition of acid to the methanol solutions of closed‐ring isomers of dibenzothienylthiazoles, the substitution of the ethoxy group with a methoxy group occurred. The generation and rearrangement of the carbocation intermediate formed by elimination of the ethoxy group from the closed‐ring isomers were apparent from the chemical structure of methoxy‐substituted products.
Impact of Fasting on Food Craving, Mood and Consumption in Bulimia Nervosa and Healthy Women Participants
Authors: Moreno‐Domínguez Silvia , Rodríguez‐Ruiz Sonia , Fernández‐Santaella M. Carmen , Ortega‐Roldán Blanca , Cepeda‐Benito Antonio 
Published: July 2012

AbstractResearchers have found that dietary restraint increases food cravings and may contribute to loss of control over eating. Negative mood states often precede food cravings and binge eating. In the present study, we tested the influence of a prolonged food deprivation period over emotional states and food cravings. Twenty‐one bulimia nervosa participants and 20 healthy women participants were asked to refrain from any eating for 20 hours and reported, at baseline, after 6 hours and at the end of the fasting period, their mood and craving states. Food consumption was also measured. Fasting increased food cravings in both groups but increased negative mood in healthy women only. Bulimia nervosa participants reported improved mood following food deprivation. Whereas Bulimia nervosa and healthy women participants ate moderate and similar amounts of food following the 20‐hour fasting period, food cravings were significantly associated with the number of calories ingested. These findings are congruent with self‐regulation theories that predict that prolonged fasting may reduce negative emotions in women with bulimia nervosa. Copyright © 2012 John Wiley & Sons, Ltd and Eating Disorders Association.
is your INTERVIEW showing?
Authors: HOOK JEANETTE WINIFRED 
Published: July 2012

I never obtained in high school any real help or advice although I did have adjustment problems. A good interviewer or adviser could have helped considerably.An adviser or counselor should be more congenial to the person being interviewed and not think an interview to be just another phase of his work and think he is obligated to be nice and talk with the interviewee.
XO: An extended ONIOM method for accurate and efficient modeling of large systems
Authors: Guo Wenping , Wu Anan , Zhang Igor Ying , Xu Xin 
Published: July 2012

AbstractCalculation of large complex systems remains to be a great challenge, where there is always a trade‐off between accuracy and efficiency. Recently, we proposed the extended our own n‐layered integrated molecular orbital (ONIOM) method (XO) (Guo, Wu, Xu, Chem. Phys. Lett. 2010, 498, 203) which surmounts some inherited limitations of the popular ONIOM method by introducing the inclusion‐exclusion principle used in the fragmentation methods. The present work sets up general guidelines for the construction of a good XO scheme. In particular, force‐error test is proposed to quantitatively validate the usefulness of an XO scheme, taking accuracy, efficiency and scalability all into account. Representative studies on zeolites, polypeptides and cyclodextrins have been carried out to demonstrate how to strive for high accuracy without sacrificing efficiency. As a natural extension, XO is applied to calculate the total energy, fully optimized geometry and vibrational spectra of the whole system, where ONIOM becomes inapplicable. © 2012 Wiley Periodicals, Inc.
The evolving field of induced pluripotency: Recent progress and future challenges
Authors: Sommer Cesar A. , Mostoslavsky Gustavo 
Published: July 2012

AbstractThe derivation of patient‐specific pluripotent cell lines through the introduction of a few transcription factors into somatic cells has opened new avenues for the study and treatment of human disorders. Induced pluripotent stem cells (iPSCs) and their derivatives offer a unique platform for disease modeling, drug discovery and toxicology, as well as an invaluable source of cells for regenerative therapies. Here, we provide an overview of the various strategies currently available for iPSC generation, highlighting recent advances and discussing some of the challenges faced in harnessing the true potential of iPSCs for biomedical research and therapeutic applications. J. Cell. Physiol. 228: 267–275, 2013. © 2012 Wiley Periodicals, Inc.
Peripheral blood mononuclear cells enhance the anabolic effects of platelet‐rich plasma on anterior cruciate ligament fibroblasts
Authors: Yoshida Ryu , Murray Martha M. 
Published: July 2012

AbstractUse of platelet‐rich plasma (PRP) has shown promise in various orthopaedic applications, including treatment of anterior cruciate ligament (ACL) injuries. However, various components of blood, including peripheral blood mononuclear cells (PBMCs), are removed in the process of making PRP. It is yet unknown whether these PBMCs have a positive or negative effect on fibroblast behavior. To begin to define the effect of PBMCs on ACL fibroblasts, ACL fibroblasts were cultured on three‐dimensional collagen scaffolds for 14 days with and without PBMCs. ACL fibroblasts exposed to PBMCs showed increased type I and type III procollagen gene expression, collagen protein expression, and cell proliferation when the cells were cultured in the presence of platelets and plasma. However, addition of PBMCs to cells cultured without platelets had no effect. The increase in collagen gene and protein expression was accompanied by an increase in IL‐6 expression by the PBMCs with exposure to the platelets. Our results suggest that the interaction between platelets and PBMCs leads to an IL‐6 mediated increase in collagen expression by ACL fibroblasts. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31:29–34, 2012