bluuebunny/crossref_metadata_2025_split huggingface dataset:
Entomotoxic action of Sambucus nigra agglutinin i in Acyrthosiphon pisum aphids and Spodoptera exigua caterpillars through caspase‐3‐like‐dependent apoptosis
Authors: Shahidi‐Noghabi Shahnaz , Van Damme Els JM , Mahdian Kamran , Smagghe Guy 
Published: September 2010

AbstractIn this project, the toxicity and mechanism of action of the ricin‐B‐related lectin SNA‐I from elderberry (Sambucus nigra) in the pea aphid (Acyrthosiphon pisum) and the beet armyworm (Spodoptera exigua), two important pest insects in agriculture, were studied. SNA‐I is a chimeric lectin belonging to the class of ribosome‐inactivating proteins and consists of an A‐chain with N‐glycosidase activity and a carbohydrate‐binding B‐chain. Incorporation of 2 mg/ml of SNA‐I in the diet of neonates and adults of A. pisum caused 40–46% mortality within 2 days, while in third instars of S. exigua, the larval biomass was significantly reduced by 12% after feeding for 3 days on a diet containing 5 mg/g of SNA‐I. Interestingly, extracts of the (mid)gut of treated A. pisum and S. exigua demonstrated DNA fragmentation and this was accompanied with an increase in caspase‐3‐like activity. The involvement of cell death or apoptosis in the entomotoxicity of SNA‐I through induction of caspase‐3‐like activity was also confirmed by addition of the permeable caspase‐3 inhibitor III in the diet, leading to a rescue of the treated aphid neonates. Finally, similar to the chimeric lectin SNA‐I, the hololectin SNA‐II, consisting of two carbohydrate‐binding B‐chains caused high mortality to neonate A. pisum aphids with an LC50 of 1.59 mg/ml, suggesting that the entomotoxic action of the lectins under study mainly relies on their carbohydrate‐binding activity. © 2010 Wiley Periodicals, Inc.
An effective radius of the sea surface enthalpy flux for the maintenance of a tropical cyclone
Authors: Miyamoto Y. , Takemi T. 
Published: September 2010

AbstractThis study found that there is a radius within which the sea surface flux for moist enthalpy plays a vital role in determining the intensity of a tropical cyclone. From the results of the numerical experiments using an axisymmetric nonhydrostatic model, it was shown that when the sea surface fluxes are modified within the radius, the intensity suddenly changes on a short timescale. As long as the surface enthalpy flux diminishes outside this radius, the tropical cyclone intensity does not decrease. In the simulated tropical cyclone, this radius locates 7–8 times the radius of the maximum wind speed. Copyright © 2010 Royal Meteorological Society
Therapeutic ultrasound to noninvasively create intracardiac communications in an intact animal model
Authors: Owens Gabe E. , Miller Ryan M. , Ensing Greg , Ives Kimberly , Gordon David , Ludomirsky Achi , Xu Zhen 
Published: September 2010

AbstractObjective: To determine if pulsed cavitational ultrasound therapy (histotripsy) can accurately and safely generate ventricular septal defects (VSDs) through the intact chest of a neonatal animal, with the eventual goal of developing a noninvasive technique of creating intra‐cardiac communications in patients with congenital heart disease. Background: Histotripsy is an innovative ultrasonic technique that generates demarcated, mechanical tissue fractionation utilizing high intensity ultrasound pulses. Previous work has shown that histotripsy can create atrial septal defects in a beating heart in an open‐chest canine model. Methods: Nine neonatal pigs were treated with transcutaneous histotripsy targeting the ventricular septum. Ultrasound pulses of 5‐μsec duration at a peak negative pressure of 13 MPa and a pulse repetition frequency of 1 kHz were generated by a 1 MHz focused transducer. The procedure was guided by real‐time ultrasound imaging. Results: VSDs were created in all pigs with diameters ranging from 2 to 6.5 mm. Six pigs were euthanized within 2 hrs of treatment, while three were recovered and maintained for 2–3 days to evaluate lesion maturation and clinical side effects. There were only transient clinical effects and pathology revealed mild collateral damage around the VSD with no significant damage to other cardiac or extra‐cardiac structures. Conclusions: Histotripsy can accurately and safely generate VSDs through the intact chest in a neonatal animal model. These results suggest that with further advances, histotripsy can be a useful, noninvasive technique to create intracardiac communications, which currently require invasive catheter‐based or surgical procedures, to clinically stabilize newborn infants with complex congenital heart disease. © 2010 Wiley‐Liss, Inc.
Expanding the base for teaching of percutaneous coronary interventions: The explicit approach
Authors: Lanzer Peter , Prechelt Lutz 
Published: September 2010

AbstractObjectives:Accelerate and improve the training and learning process of operators performing percutaneous coronary interventions (PCI).Background:Operator cognitive, in particular decision‐making skills and technical skills are a major factor for the success of coronary interventions. Currently, cognitive skills are commonly developed by three methods: (1) Cognitive learning of rules for which statistical evidence is available. This is very incomprehensive and isolates cognitive learning from skill acquisition. (2) Informal tutoring received from experienced operators, and (3) personal experience by trial‐and‐error are both very slow.Methods:We propose in this concept article a conceptual framework to elicit, capture, and transfer expert PCI skills to complement the current approach. This includes the development of an in‐depth understanding of the nature of PCI skills, terminology, and nomenclature needed to streamline communication, propensity of reproducible performance assessment, and in particular an explication of intervention planning and intra‐intervention decision‐making. We illustrate the impact of improved decision‐making by simulation results based on a stochastic model of intervention risk.Results:We identify several key concepts that form the basis of this conceptual framework, in particular different risk types and the notions of strategy, interventional module, and tactic.Conclusions:The increasing complexity of cases have brought PCI to the point where the decision‐making skills of master operators need to be made explicit to make them systematically learnable such that the skills of beginner and intermediate operators can be improved much faster than is currently possible. © 2010 Wiley‐Liss, Inc.
Long‐term outcomes of intraoperative pulmonary artery stent placement for congenital heart disease
Authors: Angtuaco Michael J. , Sachdeva Ritu , Jaquiss Robert D.B. , Morrow W. Robert , Gossett Jeffrey M. , Fontenot Eudice , Seib Paul M. 
Published: September 2010

AbstractObjective:Our objective was to examine long‐term outcomes of intraoperative pulmonary artery stents and determine risk factors for reintervention Background:Short‐term outcomes of intraoperative pulmonary artery stents have been reported previously. However, long‐term results are unknown. Methods: We conducted a retrospective review of patients who underwent intraoperative pulmonary artery stent placement for branch pulmonary artery stenosis. Results: Ninety‐six stents were implanted intraoperatively in 67 patients. Twenty‐seven patients received two or more stents at initial intervention. Median patient age at initial stent placement was 1.8 years. Median post‐inflation diameter was 8 mm. At a mean follow‐up of 7.6 ± 4.5 years, 49% of stents required reintervention (balloon angioplasty at catheterization in 28 patients and surgical revision in 19 patients). Actuarial freedom from reintervention at 2, 5, and 10 years was 68%, 49%, and 40%, respectively. In univariate analysis of time to first reintervention, age at implantation < 2 yrs (P < 0.0009) and initial post‐inflation stent diameter < 10 mm (P < 0.0002) were associated with risk for reintervention. Multivariable Cox regression analysis showed age < 2 years (P < 0.005) and diagnosis of tetralogy of Fallot (p < 0.002) or truncus arteriosus (P < 0.007) to be significant risk factors for reintervention. Conclusion: Intraoperative placement of stents in the pulmonary arteries is an alternative to surgical angioplasty, but is associated with a high incidence of reintervention. Age < 2 years and the diagnosis of tetralogy of Fallot or truncus arteriosus are risk factors for reintervention. © 2010 Wiley‐Liss, Inc.
Percutaneous revascularization of long femoral artery lesions for claudication
Authors: Connors Gerard , Todoran Thomas M. , Engelson Brian A. , Sobieszczyk Piotr S. , Eisenhauer Andrew C. , Kinlay Scott 
Published: September 2010

AbstractBackground: Angioplasty and stenting are preferred treatments for revascularizing femoral artery lesions up to 100 mm, but surgical bypass is recommended for longer lesions. We assessed long‐term patency after percutaneous revascularization of long femoral artery lesions for claudication with intensive out‐patient surveillance. Methods: We followed a cohort of 111 consecutive patients receiving angioplasty or stenting in 142 limbs in two institutions. Patients were followed for 2.5 years, and event curves and multivariable survival analysis used to compare outcomes in three groups according to lesion length (< 100 mm, 100–200 mm, and greater than 200 mm). Failed patency was defined as recurrence of symptoms with a decline in ankle brachial index, or stenosis identified by duplex ultrasound, or reintervention. Results: Compared to lesions less than 100 mm, longer lesions had higher failed primary patency (100–200 mm: HR = 2.0, P = 0.16, >200 mm: HR = 2.6, P = 0.03). Failed secondary patency was similar for short and intermediate lesions (< 5% incidence), but trended higher for lesions >200 mm (HR = 4.2, P = 0.06). An initial procedure residual stenosis greater than 20% was the only significant multivariable factor related to poorer long‐term patency (HR = 15.8, P = 0.003). Compared to short lesions, the gain in long‐term patency with out‐patient surveillance and reintervention was higher for longer lesions and significantly so for intermediate lesions (100–200 mm = 23% versus <100 mm = 8%, P = 0.041). Conclusion: Percutaneous treatment of long femoral artery lesions can provide acceptable long‐term patency for patients with claudication when out‐patient surveillance is used to identify patients who require repeat interventions. Future long‐term studies should consider overall patency encompassing more than one percutaneous reintervention. © 2011 Wiley‐Liss, Inc.
The effect of CTO recanalization on FFR of the donor artery
Authors: Sachdeva Rajesh , Uretsky Barry F. 
Published: September 2010

AbstractThis case illustrates that fractional flow reserve (FFR) in addition to the severity and length of the coronary stenosis is critically dependent on the extent of viable myocardium perfused. In the presented case, the left anterior descending artery (LAD) that had modest angiographic stenosis supplied collaterals to the entire left ventricle. After recanalization of chronic total occlusions (CTO) of the right and circumflex arteries, FFR in the LAD had normalized. © 2011 Wiley‐Liss, Inc.
Transapical repair of mitral valve paravalvular leakage using 3‐D transesophageal guidance
Authors: Swaans Martin J. , Post Martijn C. , Ten Berg Jurien M. 
Published: September 2010

AbstractWe report a case where transapical access with real time 3D transesophageal echocardiographic guidance is used for repair of a mitral valve paravalvular leakage. The transapical approach is a new, elegant, and relative safe alternative for repair of a paravalvular defect in high‐risk patients. The use of real time 3DTEE for guiding the procedure provides the operator fast and complete information about the leakage, and allowing online monitoring of the procedure. © 2010 Wiley‐Liss, Inc.
Multicatalysis: Advancing Synthetic Efficiency and Inspiring Discovery
Authors: Ambrosini Lisa M. , Lambert Tristan H. 
Published: September 2010

AbstractHeavy reliance on iterative synthetic strategies represents one of the most serious drawbacks of modern organic synthesis. There has been increasing interest of late in the development of processes that attempt to alleviate this dependence by achieving multiple transformations in a single vessel, thereby circumventing the need for intermittent isolation and purification. One such strategy is encompassed by the term multicatalysis, an approach wherein multiple catalytic reactions are executed in a single flask, either in tandem or sequentially. In this Minireview, some recent efforts in the field of multicatalysis, including our own work, are discussed. In addition, a case regarding the need for consistent terminology in this rapidly developing field is advanced.
Chiral Mesoporous Organosilica Nanospheres: Effect of Pore Structure on the Performance in Asymmetric Catalysis
Authors: Liu Xiao , Wang Peiyuan , Zhang Lei , Yang Jie , Li Can , Yang Qihua 
Published: September 2010

Abstract(R)‐(+)‐1,1′‐Bi‐2‐naphthol ((R)‐(+)‐Binol)‐functionalized (Binol=2,2′‐dihydroxy‐1,1′‐binaphthyl) chiral mesoporous organosilica nanospheres with uniform particle size (100 to 300 nm) have been synthesized by co‐condensation of tetraethoxysilane and (R)‐2,2′‐di(methoxymethyl)oxy‐6,6′‐di(1‐propyl trimethoxysilyl)‐1,1′‐binaphthyl in a basic medium with cetyltrimethylammonium bromide as the template. Nanospheres with a radiative 2D hexagonal channel arrangement exhibit higher enantioselectivity and turnover frequency than those with a penetrating 2D hexagonal channel arrangement (94 versus 88 % and 43 versus 15 h−1, respectively) in the asymmetric addition of diethylzinc to aldehydes. In addition, under similar conditions, the enantioselectivity of the nanospheres can be greatly improved as the structural order of the framework increases. These results clearly show that the structural order of nanospheres affects enantioselective reactions. The enantioselectivity of the nanospheres synthesized by the co‐condensation method is higher than that of nanospheres prepared by a grafting method and even higher than that of their homogeneous counterpart. These results indicate that the bite angle of (R)‐(+)‐Binol bridging in a more rigid porous network is in a more favorable position for achieving higher enantioselectivity. The efficiency of a co‐condensation method for the synthesis of high‐performance heterogeneous asymmetric catalysts is also reported.
A Brush‐Gel/Metal‐Nanoparticle Hybrid Film as an Efficient Supported Catalyst in Glass Microreactors
Authors: Costantini Francesca , Benetti Edmondo M. , Tiggelaar Roald M. , Gardeniers Han J. G. E. , Reinhoudt David N. , Huskens Jurriaan , Vancso G. Julius , Verboom Willem 
Published: September 2010

AbstractA polymer‐brush‐based material was applied for the formation and in situ immobilization of silver and palladium nanoparticles, as a catalytic coating on the inner wall of glass microreactors. The brush film was grown directly on the microchannel interior by means of atom‐transfer radical polymerization (ATRP), which allows control over the polymer film thickness and therefore permits the tuning of the number of nanoparticles formed on the channel walls. The wide applicability of the catalytic devices is demonstrated for the reduction of 4‐nitrophenol and for the Heck reaction.
Synthesis of a GaN Cage Compound with a Hydrazinetetraide Fragment, [NN]4−, Stabilised by Six Gallium Atoms
Authors: Uhl Werner , Rezaeirad Babak , Layh Marcus , Hagemeier Elke , Würthwein Ernst‐Ulrich , Ghavtadze Nugzar , Kuzu Istemi 
Published: September 2010

AbstractThermolysis of the bicyclic gallium hydrazide [(GaMe2)4(NHNMe)(NHNHMe)2] (1) yielded the unique cage compound [(GaMe)4(GaMe2)4(N2)(NHNMe)4] (2). Compound 2 contains a remarkable hydrazinetetraide moiety, [NN]4−, as the central structural motif which is stabilised by coordination to six gallium atoms.
Tribenzotriquinacenes Based on Regioselective Bis‐formylation: Optical Resolution and Absolute Configuration of Inherently Chiral Derivatives and Synthesis of the First Cyclophane‐Type Tribenzotriquinacene Dimers
Authors: Wang Tao , Hou Qin‐Qing , Teng Qing‐Feng , Yao Xiao‐Jun , Niu Wen‐Xue , Cao Xiao‐Ping , Kuck Dietmar 
Published: September 2010

AbstractEnantiomerically pure tribenzotriquinacenes (TBTQs) bearing two monofunctionalized aromatic nuclei were synthesized for the first time and their optical properties and absolute configuration determined. A remarkably regioselective bis‐formylation of the fully bridgehead methylated parent TBTQ hydrocarbon with MeOCHCl2/TiCl4 afforded a mixture of two Cs‐symmetrical (achiral) difunctionalized derivatives together with one C1‐symmetrical (chiral) isomer. Reduction and subsequent column chromatography furnished the three respective benzylic TBTQ dialcohols. Optical resolution of the racemic 2,6‐bis(hydroxymethyl) derivative was achieved via the diastereomeric (R)‐1,1′‐bi‐2‐naphthol ethers and the absolute configuration of the enantiomers was determined by CD exciton model analysis. The electronic circular dichroism (ECD) spectra and the specific rotation of the enantiomers were found to agree with the results of DFT calculations. Among the Cs‐symmetrical isomers, the “proximal” 2,11‐dialdehyde and the corresponding benzylic dialcohol were identified by 2D NMR spectroscopy and X‐ray crystallographic analysis, respectively, and used as the starting point for the synthesis of several novel dithiametacyclophanes. These include the first “dimeric” tribenzotriquinacene‐based cyclophanes bearing the bowls of the two TBTQ units attached to each other in a syn (concave–concave) or anti (convex–concave) configuration. The usefulness of such thiacyclophanes as fluorescent chemosensors for different metal ions is also demonstrated.
Homoleptic Zincate‐Promoted Room‐Temperature Halogen–Metal Exchange of Bromopyridines
Authors: Chau Nguyet Trang Thanh , Meyer Maxime , Komagawa Shinsuke , Chevallier Floris , Fort Yves , Uchiyama Masanobu , Mongin Florence , Gros Philippe C. 
Published: September 2010

AbstractHomoleptic lithium tri‐ and tetraalkyl zincates were reacted with a set of bromopyridines. Efficient and chemoselective bromine–metal exchanges were realized at room temperature with a substoichiometric amount of nBu4ZnLi2⋅TMEDA reagent (1/3 equiv; TMEDA=N,N,N′,N′‐tetramethylethylenediamine). This reactivity contrasted with that of tBu4ZnLi2⋅TMEDA, which was inefficient below one equivalent. DFT calculations allowed us to rationalize the formation of N⋅⋅⋅Li stabilized polypyridyl zincates in the reaction. The one‐pot difunctionalization of dibromopyridines was also realized using the reagent stoichiometrically. The direct creation of CZn bonds in bromopyridines enabled us to perform efficient Negishi‐type cross‐couplings.
ChemInform Abstract: Structure of Sr3Sc(BO3)3.
Authors: THOMPSON P. D. , KESZLER D. A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Thallium Sulfarsenites Tl3AsS3 and TlAsS2 (Thallium(I)‐ Thioarsenates(III)): Structural Characterization and Syntheses.
Authors: YANG Z.‐M. , PERTLIK F. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gas‐Phase IR Spectrum of 7‐Azaindole. Scaled Quantum Mechanical Force Field and Complete Spectrum Assignment.
Authors: CANE E. , PALMIERI P. , TARRONI R. , TROMBETTI A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isolation of a Protonated Silanol: tBu3Si(OH2)+.
Authors: XIE Z. , BAU R. , REED C. A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Synthesis of Silanes with a Stereogenic Center at Silicon via Hydrosilylation of Symmetric Ketones with Prochiral Diaryl Silanes Catalyzed by BINAP‐Rh(I) Complexes.
Authors: OHTA T. , ITO M. , TSUNETO A. , TAKAYA H. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Optically Active Aziridine Carboxylates by Lipase‐ Catalyzed Alcoholysis.
Authors: MARTRES M. , GIL G. , MEOU A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Introduction of Carbon‐Carbon Bond via Nucleophilic Aromatic Substitution.
Authors: ARTAMKINA G. A. , BELETSKAYA I. P. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactions of 1,1,2,4,4‐Pentachloro‐1‐buten‐3‐one with Mono‐ and Bifunctional Nucleophilic Reagents.
Authors: POTKIN V. I. , KABERDIN R. V. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (2 + 2) Photocycloaddition of Cinnamyloxy Silanes.
Authors: WARD S. C. , FLEMING S. A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reductive Cleavage of C‐S Bond by Samarium Diiodide: A Novel Method for the Synthesis of Disulfides and Thiolesters.
Authors: JIA X. , ZHANG Y. , ZHOU X. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.