bluuebunny/crossref_metadata_2025_split huggingface dataset:
Red blood cell alloimmunization in transfusion‐dependent Egyptian patients with thalassemia in a limited donor exposure program
Authors: El Danasoury Azza S. , Eissa Doaa G. , Abdo Reham M. , Elalfy Mohsen S. 
Published: July 2011

BACKGROUND: Thalassemia is considered the most common hemoglobinopathy in Egypt and is one of its major health problems. Lifelong red blood cell (RBC) transfusion remains the main treatment for severe forms; however, RBC alloimmunization results as a complication of regular transfusions due to repeated exposure to foreign antigens. The objective was to compare the frequency of alloantibodies in a group of patients in a limited donor exposure program (LDEP) with those receiving RBCs from multiple donors in Egyptian transfusion‐dependent patients with thalassemia.STUDY DESIGN AND METHODS: A total of 235 regularly transfused patients with thalassemia were studied, 36 of which were on LDEP. All patients were investigated for the presence of RBC autoantibodies and alloantibodies, followed by antibody identification for positive patients.RESULTS: Forty‐six (19.5%) patients developed RBC alloantibodies. The most common clinically significant alloantibodies were directed against antigens in the Kell and Rh systems. Development of alloantibodies was associated with older age, higher transfusion frequency, and splenectomy. A trend toward lower alloimmunization was elicited in the LDEP group, where 8.3% (3/36) patients were alloimmunized compared to 21.6% (43/199) in the non‐LDEP one (p = 0.057).CONCLUSIONS: Examination of donor RBCs for presence of Kell and Rh(E) antigens before transfusion can help decrease RBC alloimmunization. Further larger studies are required to assess the frequency of alloantibody production in patients on LDEP.
Donation return time at fixed and mobile donation sites
Authors: Carey Patricia M. , High Patrick M. , Schlumpf Karen S. , Johnson Bryce R. , Mast Alan E. , Rios Jorge A. , Simon Toby L. , Wilkinson Susan L. ,   for the NHLBI Retrovirus Epidemiology Donor Study‐II (REDS‐II)
Published: July 2011

BACKGROUND: This study investigated the effect of blood donation environment, fixed or mobile with differing sponsor types, on donation return time.STUDY DESIGN AND METHODS: Data from 2006 through 2009 at six US blood centers participating in the Retrovirus Epidemiology Donor Study‐II (REDS‐II) were used for analysis. Descriptive statistics stratified by whole blood (WB), plateletpheresis (PP), and double red blood cell (R2) donations were obtained for fixed and mobile locations, including median number of donations and median interdonation interval. A survival analysis estimated median return time at fixed and mobile sites, while controlling for censored return times, demographics, blood center, and mandatory recovery times.RESULTS: Two‐thirds (67.9%) of WB donations were made at mobile sites, 97.4% of PP donations were made at fixed sites, and R2 donations were equally distributed between fixed and mobile locations. For donations at fixed sites only or alternating between fixed and mobile sites, the highest median numbers of donations were nine and eight, respectively, and the shortest model‐adjusted median return times (controlling for mandatory eligibility times of 56 and 112 days) were 36 and 30 days for WB and R2 donations, respectively. For PP donations, the shortest model‐adjusted median return time was 23 days at a fixed location and the longest was 693 days at community locations.CONCLUSION: WB, PP, and R2 donors with the shortest time between donations were associated with fixed locations and those alternating between fixed and mobile locations, even after controlling for differing mandatory recovery times for the different blood donation procedures.
Fluoroscopic Left Ventricular Lead Position and the Long‐Term Clinical Outcome of Cardiac Resynchronization Therapy
Authors: FOLEY PAUL W.X. , CHALIL SHAJIL , RATIB KARIM , SMITH RUSSELL , PRINZEN FRITS , AURICCHIO ANGELO , LEYVA FRANCISCO 
Published: July 2011

Background:
To determine the effects of left ventricular (LV) lead tip position on the long‐term outcome of cardiac resynchronization therapy (CRT).
Setting:
Cardiac device therapy center.
Patients:
Five hundred and fifty‐six patients (age 70.4 ± 10.7 years [mean ± standard deviation]).
Interventions:
CRT‐pacing or CRT‐defibrillation device implantation.
Main outcome measures:
Cardiovascular mortality and events over a maximum follow‐up period of 9.1 years.
Results:
Hazard ratios (HRs [95% 785]797) for cardiovascular mortality, adjusted for age, gender, QRS duration, heart failure etiology, New York Heart Association class, and presence of diabetes and atrial fibrillation, were derived for LV lead tip positions in terms of veins, circumferential, and longitudinal positions with respect to the LV chamber. For vein position, these were 1.07 (0.74–1.56) for anterolateral vein position and 1.24 (0.79–1.95) for the middle cardiac vein, compared with a posterolateral vein. For circumferential lead tip position, HRs were 1.56 (0.73–3.34) for anterolateral and 1.57 (0.76–3.25) for lateral, compared with posterior positions. For longitudinal lead tip positions, HRs were 1.02 (0.72–1.46) for basal and 1.21 (0.68–2.17) for apical, compared with mid‐ventricular positions. The risk of meeting the composite endpoints of cardiovascular death or hospitalizations for heart failure and death from any cause or hospitalizations for major adverse cardiovascular events was similar among the various LV lead tip positions.
Conclusions:
The position of the LV lead over the LV free wall, assessed by fluoroscopy, has no influence over the long‐term outcome of CRT. (PACE 2011; 34:1–13)
Tape Casting Thin, Continuous, Homogenous, and Flexible Tapes of ZrB2
Authors: Natividad Sylvia L. , Marotto Victoria R. , Walker Luke S. , Pham David , Pinc William , Corral Erica L. 
Published: July 2011

Using an organic solvent‐based formulation, flexible and homogeneous ZrB2 tapes were cast for potential use as advanced aerospace exploration vehicles. Dispersant concentrations were optimized for attrition‐milled ZrB2 powder using gravitational sedimentation and viscosity measurements. Tape cast slurry formulations with varying amounts of binder (6–8 vol%), plasticizer (7–11 vol%), and solids loading (20–23 vol%) were used to optimize the casting slurry. An optimal slurry formulation was determined based on cast tape uniform particle distribution and flexibility without cracking. Thermal gravimetric analysis of the optimized tape was used to create a binder burnout schedule that did not alter the tape structure or particle distribution. Our organic solvent‐based tape casting approach results in minimum oxygen contamination after colloidal processing and robust cast tapes with a thickness of 280 μm and green density of ~41% theoretic density after binder burnout.
High Concentration Substitutional N‐Doped TiO2 Film: Preparation, Characterization, and Photocatalytic Property
Authors: Jiang Xudong , Wang Yongqian , Pan Chunxu 
Published: July 2011

This article introduces a novel and valid process for preparing a high concentration substitutional N‐doped TiO2 photocatalytic film, i.e. firstly the titanium substrate was plasma nitrided and then the N‐doped TiO2 was synthesized on the surface of nitrided titanium by using micro‐arc oxidation. Compared with the traditional thermal annealing, the present process provides a possibility to increase the nitrogen doping concentration up to 3.21 at.% and x to 0.11 in TiO2–xNx, which exhibits a significant red‐shift in the band‐gap transition, narrow band gap to 2.6 eV, higher photo‐generated charge carrier density and improved photocatalytic property.
Immediate Fixed Implant Rehabilitation of the Atrophic Edentulous Maxilla after Bilateral Sinus Floor Augmentation: A 12‐Month Pilot Study
Authors: Pieri Francesco , Aldini Nicolò Nicoli , Fini Milena , Marchetti Claudio , Corinaldesi Giuseppe 
Published: July 2011

ABSTRACTPurposes: The aims of this study were to evaluate a surgical/prosthetic protocol for the immediate rehabilitation of the augmented edentulous maxilla, and to compare the outcomes of implants placed in grafted (test group) versus native (control group) sites in the same patients.Materials and Methods: Twenty patients were included in the study. Each patient was treated with a bilateral sinus augmentation procedure using a 50:50 composite graft of autogenous mandibular bone and bovine hydroxyapatite. Four to 5 months later, 155 implants (90 test and 65 control) were placed and restored with screw‐retained fixed definitive prostheses supported by titanium frameworks within 1 week. All patients were followed for 1 year. Implant stability quotient (ISQ) measurements and radiographic evaluation of the marginal bone resorption (MBR) were performed.Results: Two test implants failed in two patients, giving a cumulative 1‐year success rate of 98.7%; the prostheses success rate was 100%. Insertion torque and ISQ values for test implants were significantly lower than those for control implants (unpaired t‐test, p < .0001). The mean MBR around control and test implants at the 1‐year evaluation were similar (0.47 ± 0.25 mm and 0.43 ± 0.21 mm, respectively).Conclusions: The combination of implants placed in sinus‐grafted and native sites can be immediately loaded with a fixed full‐arch prosthesis and yield short‐term successful outcomes.
Acute Inflammatory Response to Laser‐Induced Micro‐ and Nano‐Sized Titanium Surface Features
Authors: Palmquist Anders , Johansson Anna , Suska Felicia , Brånemark Rickard , Thomsen Peter 
Published: July 2011

ABSTRACTBackground: The inflammatory process induced by implant surfaces is an important component of the tissue response, where limited knowledge is available regarding the role of surface topography. With laser ablation, a combined micro‐ and nanoscale surfacemodification could be created, which have been shown to enhance bone growth and biomechanical stability in vivo.Purpose: The aim of this article was to evaluate the early in vivo inflammatory response to laser‐modified titanium disks, with machined titanium disks and sham operation sites serving as controls.Materials and Methods: Circular disks were installed in a subcutaneous rat model for 24 and 72 hours, where the cell number, cell types, and cytokine levels were evaluated.Results: The results revealed that significantly fewer inflammatory cells (mononuclear and polymorphonuclear) were attracted to the sites with the laser‐modified implants compared with the machined titanium implants. Similar concentrations of pro‐inflammatory cytokines (TNF‐a and MCP‐1), together with slightly higher cell viability, were observed around the laser‐modified surface compared with the machined surface.Conclusions: The results in the present study suggest that the combination of surface micro and nano features of the laser‐treated surface contributes to the downregulation of early inflammatory events.
A Hydrophilic Dental Implant Surface Exhibit Thrombogenic Properties In Vitro
Authors: Hong Jaan , Kurt Seta , Thor Andreas 
Published: July 2011

ABSTRACTBackground: Surface modifications of dental implants have gained attention during several years and the thrombotic response from blood components with these materials has become more important during recent years.Purpose: The aims of this study were to evaluate the thrombogenic response of whole blood, in contact with clinically used dental surfaces, Sandblasted Large grit Acid etched titanium (SLA) and Sandblasted Large grit Acid etched, and chemically modified titanium with hydrophilic properties (SLActive).Methods: An in vitro slide chamber model, furnished with heparin, was used in which whole blood came in contact with slides of the test surfaces. After incubation (60‐minute rotation at 22 rpm in a 37°C water bath), blood was mixed with ethylenediaminetetraacetic acid (EDTA) or citrate, further centrifuged at +4°C. Finally, plasma was collected pending analysis.Results: Whole blood in contact with surfaces resulted in significantly higher binding of platelets to the hydrophilic surface, accompanied by a significant increase of contact activation of the coagulation cascade. In addition, the platelet activation showed a similar pattern with a significant elevated release of β‐TG from platelet granule.Conclusions: The conclusion that can be drawn from the results in our study is that the hydrophilic modification seems to augment the thrombogenic properties of titanium with implications for healing into bone of, that is titanium dental implants.
An Interdisciplinary Treatment Approach Combining Orthodontic Forced Eruption with Immediate Implant Placement to Achieve a Satisfactory Treatment Outcome: A Case Report
Authors: Chou Yu‐Hsiang , Du Je‐Kang , Chou Szu‐Ting , Hu Kai‐Fang , Tsai Chi‐Cheng , Ho Kun‐Yen , Wu Yi‐Min , Ho Ya‐Ping 
Published: July 2011

ABSTRACTBackground: Periodontal disease often results in severely bony defects around the teeth and leads to eventual extraction. Remaining bone morphology often compromises ideally restoration‐driven positions and deteriorates the success rates for dental implants.Purpose: The present investigation illustrates the clinical outcome of immediately installing an implant following orthodontic forced eruption and atraumatic extraction.Material and Methods: The subject of this study is a 40‐year‐old Asian female with a right mandibular first molar that had a deep probing depth on the mesial side and mobility. Via the aid of radiographic examination, the tooth that had an angular bony defect and apical lesion was diagnosed as having deep caries and chronic periodontitis with a poor prognosis. After consultation with the patient, we developed a treatment plan incorporating a forced eruption with immediate implantation, intended to augment the alveolar bone volume and increase the width of keratinized gingivae, in a nonsurgical manner.Results: Following 12 months of orthodontic treatment, the tooth was successfully moved occlusally in conjunction with an 8 mm vertical interdental bone augmentation. Because of sufficient volume of bone and satisfactory gingival dimensions, the implant showed adequate initial stability in the correct position to facilitate physiological and aesthetic prerequisites. After 6 months of ossteointegration, a customized impression coping was utilized to transfer the established emergence profile to a definitive cast for the fabrication of a customized abutment. The final prosthesis was made using a customized metal abutment and ceramometal crown.Conclusion: In the face of difficult clinical challenges, meticulous inspection and a comprehensive treatment plan were crucial. Interdisciplinary treatment through the careful integration of multiple specialists suggests the possibility of optimal results with high predictability.
Comparison between Conventional and Piezoelectric Surgical Tools for Maxillary Sinus Floor Elevation. A Randomized Controlled Clinical Trial
Authors: Rickert Daniela , Vissink Arjan , Slater James J.R. Huddleston , Meijer Henny J.A. , Raghoebar Gerry M. 
Published: July 2011

ABSTRACTAim: The aim of this study was to assess the performance of conventional rotative instruments and a piezoelectric device for maxillary sinus floor elevation surgery, and to assess whether application of a resorbable membrane reduces resorption of an augmented site in a randomized clinical trial.Materials and Methods: Thirty‐six consecutive patients (59.2 ± 10.7 years, range 38–76 years) needing bilateral sinus floor elevation surgery agreed to participate in this study. In a parallel split mouth design randomized clinical trial, in which the allocation of the surgical technique to be used on the determined sites was randomly assigned, one site was always treated with conventional rotative instruments (control group) and the other site with piezosurgery (test group). In addition, in a random order, the grafted sites were covered with a collagen membrane or no membrane. After a healing period of 3–4 months implants were placed.Results: Comparison of clinical features of the test and control sites revealed no differences with regard to wound healing and complications (perforations of the sinus membrane) during or postsurgery (p = .458, p = 1.0, respectively). A clinically insignificant, but statistically shorter operation time was observed when using conventional rotative instruments (11.1 ± 2.4 minutes) than using piezosurgery (15.1 ± 2.9 minutes; p < .001). In both groups, application of a resorbable membrane did not result in less horizontal bone resorption (membrane: 1.43 mm, no membrane: 1.06 mm; p = .062); All 193 implants could be placed with primary stability. One year after functional loading, survival rate was 100%.Conclusion: It can be concluded that, for maxillary sinus floor elevation surgery, a piezoelectric device shows no advantages over rotative instruments as well as that placement of a barrier membrane did not reduce resorption of the augmented site.
Seven‐Year Follow‐Up Results of TiUnite Implants Supporting Mandibular Overdentures: Early versus Delayed Loading
Authors: Turkyilmaz Ilser , Tozum Tolga F. , Fuhrmann Dana M. , Tumer Celal 
Published: July 2011

ABSTRACTBackground and Purpose: Implant‐supported mandibular overdentures have recently become a popular treatment alternative for edentulous patients desiring increased retention of complete dentures. The goal of this study was to evaluate and present treatment outcomes of mandibular overdentures retained by two unsplinted, early‐loaded implants and compare these results with those for delayed‐loaded implants.Material and Methods: Twenty‐six edentulous patients had two interforaminal implants placed with a one‐stage protocol. The patients were each treated with a mandibular overdenture supported by ball abutments. In the test group, the overdenture was loaded 1 week after surgery and in the control group, the overdenture was loaded 3 months after surgery. Standardized clinical and radiographic parameters were recorded at surgery, and after 3, 6, 12, and 18 months, and 2, 3, 4, 5, and 7 years.Results: Because two patients did not make the 7‐year recall, only 24 patients (48 implants) were evaluated in this study. No implants were lost, and 1.31 ± 0.2 mm marginal bone resorption was noted for all implants after 7 years. Implant stability measurements, clinical peri‐implant parameters and marginal bone levels exhibited no statistically significant differences between the two groups over 7 years.Conclusion: The results of this clinical trial show that there is no significant difference in the clinical and radiographic outcomes of patients treated with mandibular overdentures supported by TiUnite implants that are either early or delayed loaded.
Efficiency and Thermal Changes during Implantoplasty in Relation to Bur Type
Authors: Sharon Eldad , Shapira Lior , Wilensky Asaf , Abu‐hatoum Rami , Smidt Ami 
Published: July 2011

ABSTRACTBackground: Implantoplasty is one of the options in treating peri‐implantitis. The efficacy of the dental bur used can reduce the time needed for the procedure and, as a consequence, minimize the risk of overheating that can negatively affect the remaining bone surrounding the implant.Purpose: The aim of this study was to evaluate the efficacy of three dental burs in removing implant substance (titanium) and to determine the amount of heat generated by each bur.Materials and Methods: Four burs with different surface properties (diamond, diamond – Premium Line, carbide, and smooth bur – control [Strauss Co., Raanana, Israel]) were attached to a high‐speed handpiece and applied to a titanium implant for a total of 60 seconds after cooling by water spray. Variations in temperature were recorded every 5 seconds, and the amount of implant substance removed (reduction in weight of the implant) was evaluated.Results: The diamond Premium Line bur removed 59.24 mg; carbide, 29.39 mg; diamond, 11.35 mg; and smooth bur (control) 0.19 mg, statistically significant. Only minimum thermal changes (∼1.5°C) were recorded for all four burs.Conclusions: There are considerable differences in efficiency of different burs working on titanium. Selecting the proper bur can reduce working time. Under proper cooling conditions, implantoplasty does not generate excess temperature increases that can damage soft tissue or bone surrounding the treated implant.
A Retrospective Analysis of Early and Immediately Loaded Osseotite Implants in Cross‐Arch Rehabilitations in Edentulous Maxillas and Mandibles Up to 7 Years
Authors: Browaeys Hilde , Defrancq Joel , Dierens Melissa C.A. , Miremadi Resa , Vandeweghe Stefan , Van de Velde Tommie , De Bruyn Hugo 
Published: July 2011

ABSTRACTBackground: Immediate loading of full‐arch restorations yields good results in selected cases, but long‐term follow‐up and the outcome in compromised bone are scarcely evaluated.Purpose: To evaluate immediately loaded Osseotite implants (Biomet 3i, Palm Beach, FL, USA) installed in healed or grafted bone, with regard to implant survival and peri‐implant bone loss up to 7 years in function.Materials and Methods: Information was retrospectively retrieved from 83 patients' records with 749 Osseotite implants supporting immediately loaded semipermanent full‐arch acrylic restorations. Five hundred sixty‐eight (75.8%) implants were placed in healed bone and 181 (24.2%) in augmented bone, regenerated with sinus lifting and/or onlay/inlay grafts with/without biomaterials and membranes. Implant survival and success based on radiological peri‐implant bone loss were registered. Wilcoxon rank sum tests evaluated peri‐implant bone loss in compromised versus healed bone or between jaws or time intervals with p < .05 as statistically significant.Results: Sixteen of 749 implants failed (2.1%), 11/343 in maxilla (3.2%) and 5/406 (1.2%) in mandible. After 7 years, the cumulative failure rate was 9%. Mean peri‐implant bone loss increased to 1.2 mm (SD 1.0) during the first 2 years but remained unchanged thereafter. Around implants in grafted bone, on average, 0.3 mm more bone loss was found.Conclusion: The Osseotite implants offer a predictable long‐term outcome in terms of implant survival and stable peri‐implant bone under immediate loading even in grafted bone. However, the high incidence of technical repair because of fractures of the semipermanent provisionals requires attention because it may be negative from a cost‐benefit perspective. Implants in grafted bone show a tendency to a more pronounced initial bone remodeling without clinical consequence in the long term.
On the occupation of X-ray-selected galaxy groups by radio active galactic nuclei since z = 1.3
Authors: Smolčić V. , Finoguenov A. , Zamorani G. , Schinnerer E. , Tanaka M. , Giodini S. , Scoville N. 
Published: July 2011

Abstract
Previous clustering analysis of low-power radio active galactic nuclei (AGNs) has indicated that they preferentially live in massive groups. The X-ray surveys of the Cosmic Evolution Survey (COSMOS) field have achieved a sensitivity at which these groups are directly detected out to z = 1.3. Making use of the surveys Chandra, XMM–Newton and VLA-COSMOS, we identify radio AGN members [1023.6≲ L1.4 GHz/(W Hz−1) ≲ 1025] of galaxy groups (1013.2≲ M200/M⊙≲ 1014.4; 0.1 &lt; z &lt; 1.3) and study (i) the radio-AGN–X-ray group occupation statistics as a function of group mass; and (ii) the distribution of radio AGNs within the groups. We find that radio AGNs are preferentially associated with galaxies close to the centre (&lt;0.2r200). Compared to our control sample of group members matched in stellar mass and colour to the radio-AGN host galaxies, we find a significant enhancement of radio-AGN activity associated with 1013.6≲ M200/M⊙≲ 1014 haloes. We present the first direct measurement of the halo occupation distribution (HOD) for radio AGNs, based on the total mass function of galaxy groups hosting radio AGNs. Our results suggest a possible deviation from the usually assumed power-law HOD model. We also find an overall increase in the fraction of radio AGNs in galaxy groups (&lt;1r200), relative to that in all environments.