bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jean-Pierre Brisset et « la folie de l'insolite » considérée du point de vue de Marcel Duchamp, d'André Breton, de Raymond Queneau, de Michel Foucault et de quelques autres
Authors: Décimo Marc 
Published: July 2012

Duchamp et Breton ont été fascinés par la littérature de Jean-Pierre Brisset, toute leur vie. Ils ont entrepris d’en parler, de l’exporter, de le rééditer, d’écrire sur, de promouvoir sa pensée. Queneau s’est passionné pour les « fous littéraires » avant d’adopter une attitude plus contrastée. Michel Foucault l’a préfacé. Quels points de vue ont-ils chacun favorisé face à cet ensemble de textes qui sont le fait d’un paraphrène ? Duchamp et Breton et les autres furent-ils des lecteurs « freudiens » (ou pas) de Brisset ?
Surréel et romantisme dans la langue allemande
Authors: Bonnellier Roseline 
Published: July 2012

Freud est un écrivain de langue allemande. En France, le surréalisme est un signe avant-coureur et un « révélateur » subconscient après coup pour la psychanalyse de son héritage « romantique ». Freud s’est arrêté chez Goethe, au « niveau de la langue » du classico-romantisme allemand. La théorie de l’Œdipe freudien en apporte la preuve « scientifique ». Hölderlin ouvre cependant à l’analyse d’un complexe d’Œdipe « inconscient » plus infini.
Revision Surgery for a Dislocated Constrained Total Knee Arthroplasty
Authors: Hagedorn Jonathan , Levine Brett R. 
Published: July 2012

Knee dislocation after revision total knee arthroplasty (TKA) is a dangerous, albeit rare, injury that can lead to neurovascular compromise and permanent disability. A paucity of peer-reviewed literature exists regarding this complication after revision TKA. Tibiofemoral dislocation commonly occurs with minimal trauma, such as rising from a seated position, and is commonly associated with a flexion–extension gap mismatch. Prompt diagnosis and expedited treatment of this complication is necessary to minimize the risk of adjacent neurovascular structures. Acute management involves attempted reduction, knee stabilization, and thorough neurovascular workup. Long-term management may require revision surgery, with the level of articular constraint necessary being determined intraoperatively.
This article describes 2 cases of relatively atraumatic knee dislocations after revision TKA involving the same semiconstrained components. Patient 1 was a 68-year-old man who sustained an atraumatic posterior knee dislocation 2 months after revision TKA. Patient 2 was a 55-year-old woman who presented after an atraumatic posterior knee dislocation 6 months after revision TKA. In both patients, a semiconstrained construct was used with corresponding revision components prior to dislocation. This article includes a synopsis of solutions for flexion–extension gap balancing and a review of the literature regarding this uncommon complication.
Anconeus Epitrochlearis as a Source of Medial Elbow Pain in Baseball Pitchers
Authors: Li Xinning , Dines Joshua S. , Gorman Matthew , Limpisvasti Orr , Gambardella Ralph , Yocum Lou 
Published: July 2012

Medial elbow pain is reported in 18% to 69% of baseball players aged of 9 and 19 years. This is due to the large valgus stresses focused on the medial side of the elbow during overhead activities. In overhead throwers and pitchers, pain can be attributed to valgus extension overload with resultant posteromedial impingement, overuse of the flexor–pronator musculature resulting in medial epicondylitis, or occasional muscle tears or ruptures. The anconeus epitrochlearis is a known cause of cubital tunnel syndrome and has been postulated as a source of medial elbow pain in overhead athletes.
This article describes the cases of 3 right-handed baseball pitchers with persistent right-sided medial elbow pain during throwing despite a prolonged period of rest, physical therapy, and nonsteroidal anti-inflammatory drugs. Two patients had symptoms of cubital tunnel syndrome as diagnosed by electromyogram and nerve conduction studies and the presence of the anconeus epitrochlearis muscle per magnetic resonance imaging. All patients underwent isolated release of the anconeus muscle without ulnar nerve transposition and returned to their previous levels of activity.
The diagnosis and treatment of pitchers who present with medial-sided elbow pain can be complex. The differential should include an enlarged or inflamed anconeus epitrochlearis muscle as a possible cause. Conservative management should be the first modality. However, surgical excision with isolated release of the muscle can be successful in returning patients with persistent pain despite a trial of conservative management to their previous levels of function.
Fibromyxoma of the Axis
Authors: Mavrogenis Andreas F. , Casadei Roberto , Gambarotti Marco , Ruggieri Pietro 
Published: July 2012

Fibromyxoma of bone is a rare benign tumor of fibrous tissue origin. The typical location is the jaws. Sporadic extragnathic cases have been reported, but fibromyxoma of the spine has not been reported. The histological appearance of fibromyxoma is benign and includes abundant extracellular fibrous and myxoid stroma with varying amounts of calcification and ossification. Myxoid changes are usually extensive. Extragnathic fibromyxoma of bone should be distinguished from benign cartilage-forming bone tumors, such as chondromyxoid and myxoid chondrosarcoma and myxoma of bone. It has also been suggested that fibromyxoma is a variant of myxoid fibrous dysplasia, whereas other authors reported extragnathic fibromyxoma resulting from myxoid degeneration of bone tumors, such as chondrosarcoma or fibrosarcoma. The overtreatment of patients with fibromyxoma of bone due to an aggressive imaging appearance should be avoided; the prognosis is excellent compared with the jaw variant and depends on the location and extent of the tumor.
This article describes a case of a 21-year-old woman with fibromyxoma of bone originating from the spinous process of the axis. Clinical examination showed a tender mass in the midline of the posterior aspect the neck and slight limitation of neck range of motion; neurologic examination was normal. Diagnosis was obtained with a preoperative biopsy. Marginal excision of the lesion with posterior laminectomy of the axis was performed. The facets were preserved, and no fusion was performed. At last follow-up 2 years after diagnosis and treatment, the patient was asymptomatic with no evidence of local recurrence.
Lumbar Decompression and Fusion in a Centenarian
Authors: Garcia Ryan M. , Belding Jonathan , Bohlman Henry H. 
Published: July 2012

The incidence of chronic and debilitating conditions in the aging population is steadily increasing, and the treatment of extreme elderly patients with spinal conditions can be challenging. Spinal stenosis and spondylolisthesis can dramatically affect patient quality of life, and patients commonly seek a surgical solution for their condition. Many extreme elderly patients are cautioned against surgery secondary due to their high complication and in-hospital mortality rates when compared with younger patients.
This article describes the oldest patient (101 years old) in the English literature with severe spinal stenosis and spondylolisthesis who underwent primary lumbar decompression and fusion. His symptomatology dramatically affected his quality of life, and he was denied surgical care at another institution secondary to his advanced age and high potential risks. A successful outcome was ultimately achieved, and he was able to return to a higher level of physical functioning and social participation prior to his death of unrelated causes 3 years later.
This case questions the strict indications of surgery in less-than-ideal and extreme elderly surgical candidates. The authors believe that surgery should not be denied in extreme elderly patients who have failed conservative treatment modalities and continue to have functional impairments. Successful spinal surgery may allow extreme elderly patients an improved quality to the remainder of their life.
Apatite Formation on Nanomaterial Calcium Phosphate/poly-DL-lactide-co-glycolide in Simulated Body Fluid
Authors: Vukelić Marija Đ. , Mitić Žarko J. , Miljković Miroslav S. , Živković Jelena M. , Ignjatović Nenad L. , Uskoković Dragan P. , Živanov-Čurlis Jelena Ž. , Vasiljević Perica J. , Najman Stevo J. 
Published: July 2012

Simulated body fluid (SBF) is an artificial fluid which has ionic composition and ionic concentration similar to human blood plasma. Purpose This paper compares the interaction between the nanomaterial containing calcium phosphate/poly-DL-lactide-co-glycolide (N-CP/PLGA) and SBF, in order to investigate whether and to what extent inorganic ionic composition of human blood plasma leads to the aforementioned changes in the material. Methods N-CP/PLGA was incubated for 1, 2, 3, and 5 weeks in SBF. The surface of the material was analyzed on SEM-EDS and FTIR spectrometer, while SBF was subjected to pH and electrical conductivity measurement. Results Our results indicate that dissolution of the polymer component of the material N-CP/PLGA and precipitation of the material similar to hydroxyapatite on its surface are based on the morphologic changes seen in this material. Conclusions The mechanism of the apatite formation on the bioceramic surface was intensively studied and was considered crucial in designing the new biomaterials. The results obtained in this work indicate that N-CP/PLGA may be a good candidate for application to bone regeneration.
Correlation between brain injury and dysphagia in adult patients with stroke
Authors: Jurkiewicz Ari Leon , Santos Rosane Sampaio , Furkim Ana Maria , Massi Giselle , Pinto Gisele Sant Ana , Lange Marcos Christiano , Nunes Maria Cristina de Alencar 
Published: July 2012

Introduction: In the literature, the incidence of oropharyngeal dysphagia in patients with cerebrovascular accident (AVE) ranges 20–90%. Some studies correlate the location of a stroke with dysphagia, while others do not.
Objective: To correlate brain injury with dysphagia in patients with stroke in relation to the type and location of stroke.
Method: A prospective study conducted at the Hospital de Clinicas with 30 stroke patients: 18 women and 12 men. All patients underwent clinical evaluation and swallowing nasolaryngofibroscopy (FEES®), and were divided based on the location of the injury: cerebral cortex, cerebellar cortex, subcortical areas, and type: hemorrhagic or transient ischemic.
Results: Of the 30 patients, 18 had ischemic stroke, 10 had hemorrhagic stroke, and 2 had transient stroke. Regarding the location, 10 lesions were in the cerebral cortex, 3 were in the cerebral and cerebellar cortices, 3 were in the cerebral cortex and subcortical areas, and 3 were in the cerebral and cerebellar cortices and subcortical areas. Cerebral cortex and subcortical area ischemic strokes predominated in the clinical evaluation of dysphagia. In FEES®, decreased laryngeal sensitivity persisted following cerebral cortex and ischemic strokes. Waste in the pharyngeal recesses associated with epiglottic valleculae predominated in the piriform cortex in all lesion areas and in ischemic stroke. A patient with damage to the cerebral and cerebellar cortices from an ischemic stroke exhibited laryngeal penetration and tracheal aspiration of liquid and honey.
Conclusion: Dysphagia was prevalent when a lesion was located in the cerebral cortex and was of the ischemic type.
Auditory middle latency response in children with learning difficulties
Authors: Frizzo Ana Claudia Figueiredo , Issac Myriam Lima , Pontes-Fernandes Angela Cristina , Menezes Pedro de Lemos , Funayama Carolina Araújo Rodrigues 
Published: July 2012

Introduction: This is an objective laboratory assessment of the central auditory systems of children with learning disabilities.
Aim: To examine and determine the properties of the components of the Auditory Middle Latency Response in a sample of children with learning disabilities.
Methods: This was a prospective, cross-sectional cohort study with quantitative, descriptive, and exploratory outcomes. We included 50 children aged 8–13 years of both genders with and without learning disorders. Those with disorders of known organic, environmental, or genetic causes were excluded.
Results and Conclusions: The Na, Pa, and Nb waves were identified in all subjects. The ranges of the latency component values were as follows: Na = 9.8–32.3 ms, Pa = 19.0–51.4 ms, Nb = 30.0–64.3 ms (learning disorders group) and Na = 13.2–29.6 ms, Pa = 21.8–42.8 ms, Nb = 28.4–65.8 ms (healthy group). The values of the Na-Pa amplitude ranged from 0.3 to 6.8 ìV (learning disorders group) or 0.2–3.6 ìV (learning disorders group). Upon analysis, the functional characteristics of the groups were distinct: the left hemisphere Nb latency was longer in the study group than in the control group. Peculiarities of the electrophysiological measures were observed in the children with learning disorders. This study has provided information on the Auditory Middle Latency Response and can serve as a reference for other clinical and experimental studies in children with these disorders.
Rehabilitation of oropharyngeal dysphagia in children with cerebral palsy: A systematic review of the speech therapy approach
Authors: Santos Rosane Sampaio , Hirata Gisela Carmona 
Published: July 2012

Introduction: There are an estimated 30,000–40,000 new cases of cerebral palsy per year in Brazil. Motor disorders caused by cerebral palsy can lead to dysphagia as they may alter the preparatory, oral, pharyngeal, and esophageal phases.
Aim: To identify existing rehabilitation methods of swallowing disorders in cerebral palsy, with emphasis on the pursuit of research using the Bobath concept, the Castillo Morales concept, oral sensorimotor therapy, and continuing education.
Summary of the findings: We performed a systematic review of the medical and speech therapy literature on the rehabilitation of oropharyngeal dysphagia in children with cerebral palsy spanning 1977–2010 and from all languages and nations. Among the 310 articles retrieved, only 22 (7.09%) addressed therapeutic rehabilitation of oropharyngeal dysphagia in children with cerebral palsy. Of the 22 reports, 12 (54.5%) were from Canada, 3 (13.6%) were from Japan, 2 (9%) were from Brazil, 2 (9%) were from Germany, 1 (4.5%) was from the USA, 1 (4.5%) was from the United Kingdom, and 1 (4.5%) was from Poland. Of these reports, 63.6% used oral sensorimotor therapy as a therapeutic method, 36.3% reported continuing education as a therapeutic approach, and only 18.1% and 9% used the Bobath concept and Castillo Morales concept, respectively.
Conclusion: Even with a constantly increasing cerebral palsy population, few studies include (re)habilitation in the treatment of oropharyngeal dysphagia in these children.
Partial glossectomy as an auxiliary method to orthodontic treatment of dentofacial deformity
Authors: Dedivitis Rogério Aparecido , Salmen Fued Samir 
Published: July 2012

Introduction: macroglossia is a condition which influences the size and shape of the teeth employed due to the forces on teeth.
Objective: To establish bases for the indication of partial glossectomy associated with orthodontic treatment and surgical dento-facial deformity in patients without tumors and Down syndrome as a cause of macroglossia.
Case reports: Three patients underwent orthognathic surgery associated with partial glossectomy under general anesthesia. All patients had macroglossia relative and underwent clinical assessment taking into account the respiratory function, swallowing and speech deficits and radiological evaluation. The technique used consist of segmental resection along the median raphe of the tongue and suture by planes. We used rigid skeletal fixation with titanium plates and screws so that patients could stay without intermaxillary block in the immediate postoperative period. Were followed over five years. The symptoms regressed completely and all skeletal segments remained stable.
Discussion: The decision to refer the patient to partial glossectomy should be based on the volume of the language, mobility, position, function, symptoms, speech intelligibility, skeletal anterior open bite, interference in orthodontic treatment, drooling, swallowing and tongue trauma applicant.
Croissance, redistribution et lutte contre la pauvreté : l’évolution non linéaire de l’approche de la Banque mondiale
Authors: Ehrhart Christophe 
Published: July 2012

Cet article passe en revue 60 années d’activités de la Banque mondiale, en mettant l’accent sur les variations dans le temps de son attitude face au combat contre la pauvreté. Durant les années cinquante et soixante, la Banque mondiale considérait que le meilleur moyen de lutter contre la pauvreté consistait à créer les conditions d’une croissance la plus forte possible en procédant à des investissements lourds dans les infrastructures physiques. Toutefois, devant la persistance de la pauvreté de masse et de fortes inégalités dans bon nombre de pays en développement malgré des performances assez satisfaisantes en termes de croissance, la Banque mondiale plaça, dès la fin des années soixante, et pour la première fois, « la guerre contre la pauvreté » au centre de son agenda puis elle s’efforça d’élaborer, pendant les années soixante-dix, de nouvelles stratégies de croissance qui soient plus favorables pour les pauvres. Sous l’ère de l’ajustement structurel, la vision de la Banque mondiale a connu également de nombreuses modifications. Durant la première moitié des années quatre-vingt, dans un contexte de crise de la dette, la Banque mondiale a été conduite à reléguer l’objectif de réduction de la pauvreté au second plan, au profit de la restauration des équilibres macroéconomiques et du potentiel de croissance des pays en difficulté. Cependant, en réponse à la critique des coûts sociaux de ses programmes d’ajustement, l’institution financière internationale a réaffirmé son engagement à lutter contre la pauvreté en accordant, dès la fin des années quatre-vingt, une plus grande importance aux conséquences sociales de l’ajustement à court terme et surtout en proposant par la suite de nouvelles stratégies de lutte contre la pauvreté à long terme.
Abacavir alters the transcription of inflammatory cytokines in virologically suppressed, HIV‐infected women
Authors: MacLeod Iain J , Rowley Christopher F , Lockman Shahin , Ogwu Anthony , Moyo Sikhulile , van Widenfelt Erik , Mmalane Mompati , Makhema Joseph , Essex M , Shapiro Roger L 
Published: July 2012

BackgroundAbacavir (ABC) may be associated with a small, increased risk of myocardial infarction in HIV‐infected adults, possibly related to cytokine‐mediated inflammation.MethodsTo evaluate the induction of inflammatory cytokine transcription by ABC, we used samples from women randomized to receive zidovudine/lamivudine/ABC (Trizivir) or lopinavir/ritonavir and zidovudine/lamividine (Kaletra/Combivir) from the third trimester through six‐months postpartum for the prevention of mother‐to‐child transmission (PMTCT). Women were matched by CD4 count and baseline HIV RNA. All women attained viral suppression (<50 copies/ml) by the time of sampling.ResultsFour cytokines showed a difference in expression between the treatment arms, all in a proinflammatory direction for the ABC arm: CD40LG 1.82‐fold, (p=.027); IL‐8 3.16‐fold (p=.020); LTA 2.82‐fold, (p=.008); and CCL5 −1.67‐fold, (p=.035). At 12‐months postpartum, 6‐months after antiretroviral discontinuation, cytokine expression was similar by treatment arm.ConclusionsWe conclude that ABC may upregulate proinflammatory cytokines at the transcriptional level in this population.
Immobilization/stabilization of acid urease on Eupergit® supports
Authors: Bortone Nadia , Fidaleo Marcello , Moresi Mauro 
Published: July 2012

AbstractThe adsorption capacity and immobilization rate of two Eupergit® supports for acid urease was studied by varying the ionic strength and enzyme preparation concentration in the immobilizing solution at pH 7. Eupergit® C250 L yielded a series of derivatives with enzyme loadings (YP/B) ranging from 48 to 171 mg of bovine serum albumin equivalent (BSAE) per gram of dry support (ds). Use of drastic postimmobilization conditions at pH 9 for 3–9 days yielded a slight decrease (8–14%) in the initial activity of immobilized enzymes and a limited increase in the stabilization factor (1.1–1.5), as assessed by accelerated aging tests at 65°C. Further storage tests at 4°C in the wet state showed that the activity of several derivatives either stabilized or not was practically constant for as long as 547 days. Both free enzyme and immobilized acid urease derivatives exhibited a kinetic pattern of the Michaelis–Menten type. Using the Eadie–Hofstee diagram, the specific ammonia formation rate constant for free (kcat) or immobilized (k′cat) enzyme resulted to be little affected by immobilization (kcat ≈ k′cat ≈ 18.86 ± 0.34 IU/mg BSAE), whereas the apparent Michaelis constant for immobilized enzymes exhibited a statistically significant increase at P < 0.05 from the intrinsic value (2.55 ± 0.14 mM) for free enzyme to 5.38 ± 0.87 mM as YP/B increased to 171 mg BSAE/g ds. By estimating the observable Thiele modulus (ϕobs), the activity of the biocatalyst with the greatest enzyme loading at the lowest urea concentrations tested (0.833 mM) was reduced by a factor of about 2 due to internal diffusional limitations. By operating in the pseudofirst‐order regime with immobilized derivatives at YP/B about 126 mg BSAE/g ds, their activity after grinding was no more limited by intraparticle diffusion and approached the value for free enzyme. © 2012 American Institute of Chemical Engineers Biotechnol. Prog., 2012
Novel Dual‐Site‐Binding Neuraminidase Inhibitor from Virtual Screening by Pharmacophore and Molecular Dynamics Methods
Authors: Huang Kun , Wu Xiaowen , Jiang Zhengyu , Sun Haopeng , You Qidong 
Published: July 2012

AbstractNeuraminidase is a significant anti‐influenza target that plays crucial role in virus replication cycle. The discovery of 150‐cavity in Group‐1 neuraminidase provides us a novel mentality of designing inhibitor which can bind with both conserved site and 150‐cavity. In order to discover novel dual‐site‐binding inhibitors, a 3D chemical‐feature‐based pharmacophore model was established to cover dual‐site in neuraminidase. The dual‐site‐binding model was consistent in predicting the binding conformation of Group‐1 neuraminidase inhibitor and applied for virtual screening of Specs database. Compound 4 (ZINC05790048) that aligned well to the model was selected after multiple filtrations for molecular dynamics simulations, indicating improved binding energy with neuraminidase. It can sever as the lead compound for a novel series of inhibitors.