bluuebunny/crossref_metadata_2025_split huggingface dataset:
A review of wearable sensors and systems with application in rehabilitation
Authors: Patel Shyamal , Park Hyung , Bonato Paolo , Chan Leighton , Rodgers Mary 
Published: April 2012

Abstract
The aim of this review paper is to summarize recent developments in the field of wearable sensors and systems that are relevant to the field of rehabilitation. The growing body of work focused on the application of wearable technology to monitor older adults and subjects with chronic conditions in the home and community settings justifies the emphasis of this review paper on summarizing clinical applications of wearable technology currently undergoing assessment rather than describing the development of new wearable sensors and systems. A short description of key enabling technologies (i.e. sensor technology, communication technology, and data analysis techniques) that have allowed researchers to implement wearable systems is followed by a detailed description of major areas of application of wearable technology. Applications described in this review paper include those that focus on health and wellness, safety, home rehabilitation, assessment of treatment efficacy, and early detection of disorders. The integration of wearable and ambient sensors is discussed in the context of achieving home monitoring of older adults and subjects with chronic conditions. Future work required to advance the field toward clinical deployment of wearable sensors and systems is discussed.
The Effect of Minocycline on the Masticatory Movements following the Inferior Alveolar Nerve Transection in Freely Moving Rats
Authors: Mostafeezur Rahman Md , Zakir Hossain Md , Yamada Yoshiaki , Yamamura Kensuke , Iwata Koichi , Sessle Barry J , Kitagawa Junichi 
Published: April 2012

Background: To determine the effects of inferior alveolar nerve transection (IAN-X) on masticatory movements in freely moving rats and to test if microglial cells in the trigeminal principal sensory nucleus (prV) or motor nucleus (motV) may be involved in modulation of mastication, the effects of microglial cell inhibitor minocycline (MC) on masticatory jaw movements, microglia (Iba1) immunohistochemistry and the masticatory jaw movements and related masticatory muscle EMG activities were studied in IAN-X rats. Results: The number of Iba1-immunoreactive (IR) cells both in prV and motV was significantly larger in IAN-X rats compared with sham rats on day 3 after IAN-X. The intraperitoneal (i.p.) administration of MC caused a significant reduction of the number of Iba1-IR cells both in prV and motV that was evident on day 14 after IAN-X. Furthermore, a significant reduction of the number of Iba1-IR cells could be observed in motV but not in prV after microinjection (m.i.) of MC into the motV of IAN-X rats. The rats also exhibited a significant decrease in the head-withdrawal threshold on the side ipsilateral to the IAN-X compared to the threshold before IAN-X and it lasted to day 14. In addition, IAN-X markedly affected the ability to rat to carry out mastication. The number of complete masticatory sequences was significantly decreased. Furthermore, the total masticatory sequence time and food preparatory (PP) period duration was significantly elongated in compared to sham rats. Although IAN-X significantly affected the total number of chewing cycles within the RC period of a masticatory sequence, it had no effect on the duration of the chewing cycles. On the other hand, systemic administration of MC (both i.p. and m.i.) in IAN-X rats significantly improved decreased head-withdrawal threshold and the impaired masticatory jaw movements. Conclusions: The present findings reveal that the strong modulation of masticatory jaw movements occurs following microglial cell activation after IAN-X, and the modulation recovers after inhibition of the microglial cell activation by MC, suggesting that microglial cell activation in the motV as well as in the prV has a pivotal role in modulating mastication following trigeminal nerve injury associated with orofacial neuropathic pain.
Effect of sequential treatment with syndrome differentiation on acute exacerbation of chronic obstructive pulmonary disease and "AECOPD Risk-Window": study protocol for a randomized placebo-controlled trial
Authors: Haifeng Wang , Jiansheng Li , Suyun Li , Xueqing Yu , Hailong Zhang , Zhiwan Wang , Qiyi Wu , Pankui Zhang , Zhongchao Wang , Fenglei Li , Haihong Yan 
Published: April 2012

Abstract

Background
Frequent chronic obstructive pulmonary disease (COPD) exacerbation is a major cause of hospital admission and mortality. It has been reported that Traditional Chinese Medicine (TCM) may relieve COPD symptoms and reduce the incidence of COPD exacerbations, thus improving life quality of COPD patients. The acute exacerbation of COPD risk-window (AECOPD-RW) is the period after an exacerbation and before the patient returns to baseline. In the AECOPD-RW, patients are usually at increased risk of a second exacerbation, which may lead to hospital admission and high mortality. It may be beneficial for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients to receive interventions during AECOPD-RW. During exacerbations the treatment principle is to eliminate exogenous pathogens, whereas the AECOPD-RW treatment principle focuses on enhancing body resistance.

Methods/Design
A prospective, multi-center, single-blinded, double-dummy and randomized controlled clinical trial is being conducted to test the therapeutic effects of a sequential two stage treatment, which includes eliminating pathogen and strengthening vital qi with syndrome differentiation. A total of 364 patients will be enrolled in this study with 182 in each treatment group (TCM and control). Patients received medication (or control) according to their assigned group. TCM for AECOPD were administered twice daily to patients with AECOPD over 7 to 21 days, followed by TCM for AECOPD-RW over 28 days. All patients were followed for six months. The clinical symptoms, the modified medical research council dyspnea (MMRC) scale and exacerbations were used as the primary outcome measures. Pulmonary function, quality of life and mortality rate were used as secondary outcome measures.

Discussion
It is hypothesized that sequentially eliminating pathogens and strengthening vital qi treatments with syndrome differentiation will have beneficial effects on reducing the frequency and duration of acute exacerbation, relieving symptoms and improving quality of life for COPD patients.

Trial registration
This study is registered at ClinicalTrials.gov, ChiCTR-TRC-11001460.
Intravenous magnesium prevents atrial fibrillation after coronary artery bypass grafting: a meta-analysis of 7 double-blind, placebo-controlled, randomized clinical trials
Authors: Gu Wan-Jie , Wu Zhen-Jie , Wang Peng-Fei , Aung Lynn Htet Htet , Yin Rui-Xing 
Published: April 2012

Abstract

Background
Postoperative atrial fibrillation (POAF) is the most common complication after coronary artery bypass grafting (CABG). The preventive effect of magnesium on POAF is not well known. This meta-analysis was undertaken to assess the efficacy of intravenous magnesium on the prevention of POAF after CABG.

Methods
Eligible studies were identified from electronic databases (Medline, Embase, and the Cochrane Library). The primary outcome measure was the incidence of POAF. The meta-analysis was performed with the fixed-effect model or random-effect model according to heterogeneity.

Results
Seven double-blind, placebo-controlled, randomized clinical trials met the inclusion criteria including 1,028 participants. The pooled results showed that intravenous magnesium reduced the incidence of POAF by 36% (RR 0.64; 95% confidence interval (CI) 0.50-0.83; P = 0.001; with no heterogeneity between trials (heterogeneity P = 0.8, I
2 = 0%)).

Conclusions
This meta-analysis indicates that intravenous magnesium significantly reduces the incidence of POAF after CABG. This finding encourages the use of intravenous magnesium as an alternative to prevent POAF after CABG. But more high quality randomized clinical trials are still need to confirm the safety.
Epididymis rhabdomyoma: A case report and literature review
Authors: Han Yang , Qiu Xue-shan , Li Qing-chang , Han Yu-chen , Lin Xu-yong , Zhang Qing-fu , Wang Jian , Wang En-hua , Li Ze-liang 
Published: April 2012

Abstract
Genital rhabdomyoma is very rare tumor that usually occurs in the vulvar of young women. Epididymis rhabdomyoma in a young man is extremely uncommon and has rarely been reported. Here, we report a case of epididymis rhabdomyoma of a 17-year-old man and review the literatures.

Virtual slide

The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1177628224692794
Teaching human parasitology in China
Authors: Zhao Guanghui , He Shenyi , Chen Lin , Shi Na , Bai Yang , Zhu Xing-Quan 
Published: April 2012

Abstract
China has approximately one-fifth of the world’s population. Despite the recent success in controlling major parasitic diseases, parasitic diseases remain a significant human health problem in China. Hence, the discipline of human parasitology is considered as a core subject for undergraduate and postgraduate students of the medical sciences. We consider the teaching of human parasitology to be fundamental to the training of medical students, to the continued research on parasitic diseases, and to the prevention and control of human parasitic diseases. Here, we have summarized the distribution of educational institutions in China, particularly those that teach parasitology. In addition, we have described some existing parasitology courses in detail as well as the teaching methods used for different types of medical students. Finally, we have discussed the current problems in and reforms to human parasitology education. Our study indicates that 304 regular higher education institutions in China offer medical or related education. More than 70 universities have an independent department of parasitology that offers approximately 10 different parasitology courses. In addition, six universities in China have established excellence-building courses in human parasitology.
Early neurovascular uncoupling in the brain during community acquired pneumonia
Authors: Rosengarten Bernhard , Krekel Dennis , Kuhnert Stefan , Schulz Richard 
Published: April 2012

Abstract
Introduction
Sepsis leads to microcirculatory dysfunction and therefore a disturbed neurovascular coupling in the brain. To investigate if the dysfunction is also present in less severe inflammatory diseases we studied the neurovascular coupling in patients suffering from community acquired pneumonia.

Methods
Patients were investigated in the acute phase of pneumonia and after recovery. The neurovascular coupling was investigated with a simultaneous electroencephalogram (EEG)-Doppler technique applying a visual stimulation paradigm. Resting EEG frequencies, visual evoked potentials as well as resting and stimulated hemodynamic responses were obtained. Disease severity was characterized by laboratory and cognitive parameters as well as related scoring systems. Data were compared to a control group.

Results
Whereas visually evoked potentials (VEP) remained stable a significant slowing and therefore uncoupling of the hemodynamic responses were found in the acute phase of pneumonia (Rate time: control group: 3.6 ± 2.5 vs. acute pneumonia: 1.6 ± 2.4 s; P < 0.0005). In the initial investigation, patients who deteriorated showed a decreased hemodynamic response as compared with those who recovered (gain: recovered: 15% ± 4% vs. deteriorated: 9% ± 3%, P < 0.05; control: 14% ± 5%). After recovery the coupling normalized.

Conclusions
Our study underlines the role of an early microcirculatory dysfunction in inflammatory syndromes that become evident in pre-septic conditions with a gradual decline according to disease severity.
Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis
Authors: Oehlers Stefan H. , Flores Maria Vega , Hall Christopher J. , Crosier Kathryn E. , Crosier Philip S. 
Published: April 2012

Summary
Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking retinoid treatment to IBD; however, there is little direct evidence for this interaction. The zebrafish larva is an emerging model system for investigating the pathogenesis of IBD. Importantly, this system allows components of the innate immune system, including mucus physiology, to be studied in isolation from the adaptive immune system. This study reports the characterization of a novel zebrafish larval model of IBD-like enterocolitis induced by exposure to dextran sodium sulfate (DSS). The DSS-induced enterocolitis model was found to recapitulate several aspects of the zebrafish trinitrobenzene-sulfonic-acid (TNBS)-induced enterocolitis model, including neutrophilic inflammation that was microbiota-dependent and responsive to pharmacological intervention. Furthermore, the DSS-induced enterocolitis model was found to be a tractable model of stress-induced mucus production and was subsequently used to identify a role for retinoic acid (RA) in suppressing both physiological and pathological intestinal mucin production. Suppression of mucin production by RA increased the susceptibility of zebrafish larvae to enterocolitis when challenged with enterocolitic agents. This study illustrates a direct effect of retinoid administration on intestinal mucus physiology and, subsequently, on the progression of intestinal inflammation.
Renal Cell Carcinoma Associated With Transcription Factor E3 Expression and Xp11.2 Translocation
Authors: Klatte Tobias , Streubel Berthold , Wrba Friedrich , Remzi Mesut , Krammer Barbara , de Martino Michela , Waldert Matthias , Marberger Michael , Susani Martin , Haitel Andrea 
Published: April 2012

Abstract
We studied the characteristics and prognosis of renal cell carcinoma (RCC) associated with Xp11.2 translocation and transcription factor E3 (TFE3) expression and determined the need for genetic analysis in routine diagnostics. Of 848 consecutive cases, 75 showed microscopic features suggestive of Xp11.2 translocation RCC or occurred in patients 40 years or younger. Of these cases, 17 (23%) showed strong nuclear TFE3 immunostaining, which was associated with more advanced tumors and inverse prognosis in univariate (P = .032) but not multivariate (P = .404) analysis. With fluorescence in situ hybridization and polymerase chain reaction, only 2 cases showed alterations of the X chromosome and the ASPL-TFE3 gene fusion, respectively. In our laboratory, the predictive value of TFE3 expression for the Xp11.2 translocation was 12%. Strong nuclear TFE3 expression is associated with metastatic spread and a poor prognosis. In our laboratory, TFE3 is not diagnostic for Xp11.2 translocation RCC. Diagnosis of Xp11.2 translocation RCC may be made only genetically.
New Gymnamoebae Species (Gymnamoebia) in the Fauna of Ukraine
Authors: Patsyuk M. 
Published: April 2012

New Gymnamoebae Species (Gymnamoebia) in the Fauna of Ukraine
Information is given on new in the fauna of Ukraine gymnamoebae species: Saccamoeba stagnicola Page, 1974; Mayorella sp.; Korotnevella sp.; Paradermamoeba levis Smirnov et Goodkov, 1994; Paradermamoeba valamo Smirnov et Goodkov, 1993 and Stenamoeba stenopodia Smirnov, Nassonova, Chao et Cavalier-Smith, 2007.
New and Formerly Unknown Ormyridae Species from the United Arab Emirates (Hymenoptera, Chalcidoidea)
Authors: Zerova M. , Seryogina L. , Van Harten A. 
Published: April 2012

New and Formerly Unknown Ormyridae Species from the United Arab Emirates (Hymenoptera, Chalcidoidea)
Three new species (Ormyrus qurrayahi Zerova, sp. n., O. punctellus Zerova, sp. n. and O. novus Zerova, sp. n.) are described. Two first species belong to diffinis species group (female gaster without dorsal median keel). O. novus sp. n. belongs to orientalis species group (female gaster with dorsal median keel). In addition, two Palaearctic species of the genus Ormyrus are recorded from the United Arab Emirates for the first time. A key to Palaearctic Ormyrus species is provided.
First Record of the Boreal-Arctic Marine Leech Mysidobdella Borealis (Hirudinida, Piscicolidae) from the Southern Bay of Biscay
Authors: Utevsky S. , Sorbe J. 
Published: April 2012

First Record of the Boreal-Arctic Marine LeechMysidobdella Borealis(Hirudinida, Piscicolidae) from the Southern Bay of BiscayFour individuals of the marine fish leechMysidobdella borealis(Johansson, 1898) were sampled from the mysidsSchistomysis parkeriNorman, 1892 from the swash zone of Hendaye beach, France. This is the only known so far boreal-arctic piscicolid species occurring from the southern Bay of Biscay to the Kara Sea.
Reassesment of the Spider Genus Clubiona (Aranei, Clubionidae)
Authors: Mikhailov K. 
Published: April 2012

Reassesment of the Spider Genus Clubiona (Aranei, Clubionidae)
The spider genus Clubiona Latreille, 1804 is reestablished in its traditional scope. Taxonomical characters of infrageneric groupings are discussed. Tribes within the Clubioninae sensu Wunderlich (2011) are not accepted. Diagnosis and short description of Clubiona s. l., as well as a provisional key to clubionid genera, are provided. The following synonymies are established: Epiclubiona Lohmander, 1945, syn. n.; Euryclubiona Lohmander, 1945, syn. n.; Gauroclubiona Lohmander, 1945, syn. n.; Heteroclubiona Lohmander, 1945, syn. n.; Hyloclubiona Lohmander, 1945 syn. n.; Microclubiona Lohmander, 1945, syn. n.; Porrhoclubiona Lohmander, 1945, syn. n.; Anaclubiona Ono, 2010, syn. n.; Breviclubiona Wunderlich, 2011, syn. n.; Marmorclubiona Wunderlich, 2011, syn. n. = Clubiona Latreille, 1804, s. l.
Basic Hope And Generativity In Middle Adulthood
Authors: Wojciechowska Ludwika 
Published: April 2012

Basic Hope And Generativity In Middle Adulthood
The aim of the presented research was to investigate the relationship between the level of basic hope and the level and type of generativity in persons in middle adulthood. Hypotheses were posited and a positive correlation relationship was expected between basic hope and generativity, as well as a stronger relationship between those variables in the group of women than in the group of men, as well as a stronger relationship in the group of persons with a higher level of education than in the group of persons with a lower level of education. A sample of 120 persons was studied, of which 70 were women and 50 constituted men aged between 40-65 years. Two measurement instruments were used - one to diagnose generativity (author's own instrument), and the second to measure basic hope devised by Trzebiński and Zięba. The results of the conducted research have confirmed the posited hypotheses.
The Significance Of Adolescent's Value System In Creating Concept About Their Own Life
Authors: Czerwińska-Jasiewicz Maria 
Published: April 2012

The Significance Of Adolescent's Value System In Creating Concept About Their Own Life
This paper presents a study on the significance of adolescent's value system in creating concept about their own life in the process of planning their own future. A hypothetical model of this concept is analysed, which identifies such main components as: preferred life style, life goals and plans, and decisions concerning their own future. This model acknowledges values as the main criterion in creating this concept as they form the base for defining a person's preferred life style, their formulation of life goals and plans and the undertaking of important decisions concerning their future (Czerwińska-Jasiewicz, 2005). The propounded author's own model of adolescents' concepts about their own future has been based on the notion of J. Piaget (Inhelder, Piaget, 1970), concerning adolescents creating a "programme" of their own life, as a specific developmental task during adolescence. The statement that the "programme" of adolescents' own lives is based on a given value scale on which certain ideals and goals can be placed above others seems particularly significant in this concept. The discussion presented herein is based on the above statement. The creation by me of the above model was further inspired by the theoretical concepts and the research programmes concerning the future orientation of adolescents, their goals and life plans and values (Nuttin, 1980; Niemczyński, 1980, 1988; Nurmi, 1991; Matusewicz, 1975; Mądrzycki, 1996; Zaleski, 1991; Trempała, 1996, 2000).
Humor From The Perspective Of Positive Psychology. Implications For Research On Development In Adulthood
Authors: Radomska Anna 
Published: April 2012

Humor From The Perspective Of Positive Psychology. Implications For Research On Development In Adulthood
The purpose of the article is the presentation of the ways that humor was understood within the current of positive psychology; the state and advances of research on the significance of this property in achieving and safeguarding a "good life" as well as the legitimacy and possibility of applying the theoretical and research approach devised by the mentioned orientation approaches to issues connected with humor to the field of developmental psychology during the life course. A conceptualisation of humor was presented as a character strength comprising the virtue of transcendence in the approach of Peterson and Seligman, a composite of wisdom in the concept of Webster and of a thinking style, experiencing and action in the theory of Martin. A review of research was then undertaken: humor as a virtue imbuing property; humor correlates understood from the perspective of positive psychology; manifestations of its regulative role and individual differences in humor as a resource contributing to individual growth. In the closing paragraphs a suggestion was formulated regarding humor research as a resource that supports positive development, namely, the fulfilment of developmental tasks, overcoming developmental crises and coping with problems connected with ageing.
Belief in the causative power of words as a manifestation of magical thinking in late childhood
Authors: Bieńkowska Agnieszka 
Published: April 2012

Belief in the causative power of words as a manifestation of magical thinking in late childhood
The purpose of the research was to present one of the manifestations of magical thinking in late childhood, i.e. belief in the causative power of words, and relations between this phenomenon and language. One hundred and three primary school students (43 girls and 60 boys), grades 4 to 6, aged 10 to 13 were studied. A significant relation was found between belief in the direct effect of words on reality, and correct comprehension and number of phraseological units concerning the causative power of words.