bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electronic Assessment in Learning Institutions as an agent of Green Economy
Authors: Kosgey James 
Published: February 2025

Electronic assessment, also known as E-assessment is the use of technology to manage and deliver assessments which vary from multiple choice quizzes to essay based questions. E-learning has greatly contributed to wide use of online teaching but so far, E-assessment has not been widely embraced which could have contributed to efficiency in teaching, learning and assessment. The objective of this research was to: establish how students view the e-assessment website pages user interface; find out how system use of the e-assessment site contributed to overall usability, and to determine student perception towards online assessment. Qualitative research was used as a research design to establish the various e-assessment tools that are commonly used in learning institutions. Modular Object-Oriented Dynamic Learning Environment (Moodle) was found to be the common e-learning content management system that offered trainer friendly e-assessment platform. Questionnaires were used as a data collection tool to obtain data from 46 students on their views on e-assessment in learning based on User Interface and System Use Perspective. The sample was selected purposively from a population of students who had been exposed to e-assessment. The students reported that e-assessment was much better because of easy user interface, automated marking and immediate release of results. The institution would greatly benefit by saving costs for printing exams by fully implementing e-assessment. This paper addresses an evaluation of electronic assessment tools that are in use. It identifies the user interface issues that can be addressed as well as a couple of system use concerns. It identifies the need for constant feedback from the users of the system in order to improve electronic assessment.
The Influence of Stakeholders in Project Monitoring and Evaluation on Sustainability of Water Projects in Kwanza Sub-County Kenya
Authors: Aupe Naker Diana , Sagwa Evans Vidija 
Published: February 2025

The objective of the study was to find out the influence of stakeholders in project monitoring and evaluation on sustainability of water projects in Kwanza Sub-county. The study was guided by Community Participation Theory and Sustainability Theory. A descriptive survey research design was used. The target population of the study was 32,181 households in Kwanza Sub-County, Trans-Nzoia County. The researchers used the Sekaran sample size determination formula to obtain a sample size of 380 households. The researchers used simple random sampling to select the households. The study used a questionnaire to collect data. The researchers pre-tested the questionnaire on 38 households in the neighboring Kiminini Constituency. The researchers ensured and enhanced the validity of the data collection instrument by seeking advice from two experts on matters of water and irrigation. The researchers used the split-half method to compute the reliability of the instrument. The researchers observed ethical consideration such as informed consent, and confidentiality. Data analysis was aided by SPSS computer software. Quantitative data was analyzed using both descriptive and inferential statistics. Descriptive analysis generated frequencies, percentages, proportions, mean and standard deviation while inferential analysis generated Pearsonâ€™s correlation to show the association between the dependent and the independent variable. The study found that there was a significant moderate positive correlation between stakeholder participation in monitoring and evaluation and sustainability of water projects, where the Spearman's rho(r) = 0.496, p=0.010, CL=95%.The study recommends that the government and other development agencies should enhance stakeholder participation in project monitoring and evaluation for sustainability of water projects for faster realization of Kenya Vision 2030 goals. Further studies should be conducted to establish the moderating effect of project leadership on the relationship between stakeholder participation and sustainability of water projects in Kwanza Sub-County, Kenya
The Influence of Physical Facilities on the Teaching-Learning Process in Public Primary Schools in Bungoma County, Kenya
Authors: Etale Ochwada Youanita , Oseko Agnes , Murunga Felicity 
Published: February 2025

This paper presents the findings of a study undertaken to investigate the influence of sufficiency of physical facilities on the teaching-learning process in public primary schools in Bungoma South Sub-County, Bungoma County, Kenya. The findings of this study will be significant to the Ministry of Education in terms of providing additional information for policy formulation in public primary schools. Descriptive survey research design was used. The target population was the head teachers/deputy head teachers, class teachers, and pupils in the public primary schools in Bungoma South Sub-County, Bungoma County. A combination of stratified sampling, simple random sampling and purposive sampling were used. In a case where there was more than one stream in a class, simple random sampling was used to select one class teacher from each stream. A sample size of 30 % of the target population was used. Primary data was used and collected using questionnaires and focus group discussions. Results of this study showed that sufficiency of physical facilities - specifically adequacy of classrooms significantly affect the teaching-learning process. Those who reported having adequate classrooms performed better than those who reported inadequacy (Z=1.776, 0.046). The study concluded that among the physical facilities, adequacy of classrooms was the only factor that significantly affected teaching and learning whereby adequate classrooms positively affected, while inadequate classrooms negatively affected teaching and learning. The study therefore recommends that national and county governments should ensure that classrooms are adequate in public primary schools.
COMPARATIVE THERAPEUTIC POTENTIAL OF ANTIBIOTIC LOADED GOLD AND SILVER NANOCONJUGATES IN CANCER THERAPY
Authors: Zehra Dabeeran , Shumaila Usman  , Kauser Ismail  , Shamaila Khalid  , Syed Saud Hasan  , Sadia Arif  
Published: February 2025

Background: Nanomedicine is believed to be an emerging field to improve the efficacy of conventional chemotherapy. Nanoparticles (NPs), particularly drugs conjugated nanometals, have garnered attention as distinct drug carriers in terms of improved pharmacokinetic and pharmacodynamic properties compared to traditional formulations. This study aimed to investigate the potential of silver and gold-loaded antibiotic Azithromycin in demonstrating tumour-suppressing behaviour. Methods: Cells after being treated with different working concentrations of drugs/compounds Azithromycin, Au-Azithromycin and Ag-Azithromycin. After obtaining IC50 concentrations, treatment groups were further analysed for morphological changes under an inverted phase microscope after 24 and 48 hours of treatment. Finally RT-PCR (Reverse transcription polymerase chain reaction) was performed to evaluate the effect of these treatment groups on the regulation of Rapidly Accelerated Fibrosarcoma-1 (Raf-1), and Mitogen-Activated Protein Kinase 3 (MAPK3) involved in cancer proliferation. GAPDH was used as control gene which is a reference gene used in comparisons of gene expression data. Results: Compared to control, all the treatment groups showed very highly significant (p<0.001) down regulation of MAPK3 while Raf-1 exhibited highly significant (p<0.01) down regulation in all treatment groups. Conclusion: Azithromycin loaded with metallic nanoparticles such as gold and silver showed significant suppression of proliferative genes involved in the MAP kinase signalling pathway.
Pak J Physiol 2024;20(4):8-12, DOI: https://doi.org/10.69656/pjp.v20i4.1641
ENVELHECIMENTO SAUDÁVEL: AVANÇOS QUE APOIAM O CONSTRUTO DA CAPACIDADE INTRINSECA EM IDOSOS
Authors: Vasconcelos Kamilla de Brito , Costa Lilian Conceição Coelho 
Published: February 2025

Introdução: Em busca da promoção e preservação do envelhecimento saudável, novas estratégias de saúde têm sido empregadas, a capacidade intrínseca surge para reestruturar o que se conhecia como marcador de envelhecimento saudável, pois se baseia nas reservas biológicas residuais e não somente no número de comorbidades. Objetivo: Verificar estudos que apoiam a construção da avaliação da capacidade intrínseca como medida de envelhecimento saudável. Metodologia: Trata-se de uma revisão de literatura, do tipo scoping review, utilizando as bases de dados Medline, PEDro e Scielo. Resultados: Foram encontrados na primeira busca 96 artigos a respeito do tema, após a análise, restaram 36 artigos relevantes e posteriormente, após uma análise mais criteriosa, 13 artigos foram elegíveis para esta pesquisa. Considerações Finais: A capacidade intrínseca mostrou-se um instrumento promissor para a construção de estratégias que auxiliem na avaliação e ajudem a preservar o envelhecimento saudável.
Tratamento Intervencionista na Cirrose Hepática: Abordagens e Resultados
Authors: Costa Déborah Figueira da , Marini Karina Dupim , Baracat Maria Luiza Chaves , Oliveira Geórgia Terceiro de , Silva Fellipe Ariel de Lucena , Gonçalves Kethlen de Souza , Dantas Daniel Loureiro , Teixeira Beatriz Pessanha Dias , Detoni Ana Luísa Macacchero , Miranda Jéssica Lourenço , Martins Mariane Silva Oliveira , Carvalho Raissa de , Martins Jucemara Vieira , Oliveira Larissa Barbosa de , Infante Nathália Cristine Ferreira 
Published: February 2025

O presente estudo revisou o tratamento intervencionista na cirrose hepática, utilizando uma abordagem de revisão integrativa. O objetivo foi avaliar a eficácia e os desfechos clínicos das diferentes estratégias intervencionistas no manejo da cirrose hepática. A metodologia consistiu em uma revisão integrativa realizada nas bases de dados Scientific Electronic Library Online (SCIELO), Cochrane e Medline, utilizando descritores de ciências da saúde relacionados ao tema, como “Liver Cirrhosis”, “Case Management” e “Patient Care”. Os resultados mostraram que o tratamento intervencionista na cirrose hepática pode melhorar a função hepática e reduzir complicações, proporcionando melhor controle da doença. As abordagens terapêuticas demonstraram eficácia em estágios avançados, promovendo alívio dos sintomas e melhor qualidade de vida.
Planteamiento estratégico del producto vino tinto soprano en tiendas TUTI
Authors: Campozano Baquerizo Nathaly Geanella , Astudillo Naranjo Laura Marivel , Valarezo Perugachi José Luis 
Published: February 2025

El consumidor no solo busca buen precio, sino también calidad, facilidad en el sistema de compras y que el producto complemente una emotividad en su momento de consumirlo. Por ello, se ve obligado a buscar productos que cumplan sus necesidades y expectativas. Por esta razón, desde hace algunos años los mismos fabricantes han hecho un gran cambio en la presentación y publicidad de sus marcas más reconocidas, buscando la diferenciación de sus competidores y un mayor acercamiento al posicionamiento de la marca en la mente del consumidor (Cuenca et al., 2020). La presente propuesta tiene como objetivo desarrollar el planeamiento estratégico del producto vino tinto “soprano” en tiendas TUTI Babahoyo, Ecuador. Se realizo una metodología explicativa con un diseño descriptivo. La muestra para nuestro proyecto consistió en 50 clientes que compran el vino en la tienda TUTI Babahoyo Mamey en el 2024, para analizar las razones por las cuales ellos deciden comprar ese producto y compararlo con nuestro diseño y planificación de este producto que ha caracterizado en ser popular. Se realizo el análisis de las encuestas, el resumen y reporte de datos, para mostrar la información de una forma más completa; también se ejecutará un análisis previo para codificar los datos de las encuestas y su respectivo procesamiento para conducir a una mejor comprensión de los datos de estudio y por último se esbozó un marco analítico representado por tablas, gráficas y perfiles para organizar los resultados. El vino tinto soprano es un vino que cubre las necesidades y demanda del mercado local: un vino fresco, moderno y fácil de beber. Existe un alto índice de conocimiento de este vino en el mercado local con un 98 %, mientras que solo el 2 % desconoce el vino tinto soprano. En relación a las personas encuestadas se pudo evidenciar que el 100 % les ha gustado el vino tinto soprano en su consumo. Los puntos cualitativos preferidos por los consultados del producto son es barato (80 %), es de calidad (10 %), me gusta (10 %), ninguna (0 %). El consumidor compraría a un precio económico $4 el 92 % de los encuestados, mientras que otros comprarían a $ 3.50 (6 %) y a $ 5. 00 (2 %). El 60 % de los encuestados en tiendas Tuti compran entre 1-2 botellas al día, con lo cual existe una buena demanda del producto, mientras que otras personas comprarían entre 3-4 botellas al día (24 %) y otros más de >4 botellas al día (16 %). El ciclo de vida del vino soprano está dividido en tres etapas principales: La viticultura, es decir, el cultivo de la uva; La elaboración del vino y su embotellado y La distribución y venta. La marca de vino tinto soprano expendida en la tienda Tuti Babahoyo Mamey, es un producto que responde a una demanda exigida por los del vino tinto soprano, lo cual refleja la calidad y el precio accesible para los consumidos que prefieren este producto.
Educación ambiental a través de las redes sociales, un análisis bibliométrico
Authors: Herrera Cuéllar Tatiana , Losada Salgado Néncer 
Published: February 2025

La Educación Ambiental es concebida como una estrategia que permite mejorar las actitudes del ser humano con la naturaleza (Amézquita et al., 2023), sus conocimientos y prácticas ambientales (Hungerford et.al., 2013). La Educación Ambiental no solo busca transmitir conocimientos, sino también fomentar valores y habilidades que promuevan la acción proambiental. En este contexto, las redes sociales han adquirido una importancia creciente, convirtiéndose en un canal de comunicación clave para el intercambio de conocimientos, el fortalecimiento de la conciencia ambiental y la movilización de audiencias a nivel global (Carvalho et al., 2021). El presente artículo tiene como objetivo identificar las tendencias de investigación sobre educación ambiental a través de las redes sociales. Para ello, se emplearon los datos de la base Scopus, abarcando un periodo entre 2012 y 2024. La muestra final incluyó 69 artículos, que fueron procesados mediante los softwares VOSviewer, el paquete R bibliometrix y la aplicación Biblioshiny. Entre los hallazgos más destacados, la revista Sustainability se posiciona como la principal fuente de publicaciones sobre este tema, con 11 artículos desde el 2012. El autor con más publicaciones en esta área es Wang Y. et al., (2024), quien ha realizado múltiples contribuciones al campo. Asimismo, el artículo más citado corresponde a Rahim et al., (2012), con un total de 53 citas. Las palabras de mayor coocurrencia incluyen "social media", "environmental education" y "sustainability". Las redes sociales han emergido como un medio eficaz y flexible para la educación ambiental, facilitando el acceso a contenidos pedagógicos, promoviendo la interacción social y el activismo digital, y ampliando las posibilidades de investigación y enseñanza.
Blockchain-based System for Secure Generation and Certification of Bank Cheques
Authors: Bello Abdou Wahidi , Djara Tahirou , Ceci Mohamed Salim Sidi 
Published: February 2025

Cheques are a means of payment. It is a vehicle for so-called scriptural money. Because of its cashless nature, cheques are subject to shortcomings in terms of both security and ease of use. This article presents a system for dematerialising cheques, facilitating their certification and tracking through the use of revolutionary web3 technologies such as blockchain, interplanetary file systems and decentralised applications. The system relies on the Ethereum blockchain, whose Proof-of-Work (PoW) consensus mechanism guarantees the security and integrity of transactions through decentralized block validation. Until now, issuing a cheque has required the physical contribution and presence of both the drawer and the bearer. We enable the drawer to digitally issue and manage a cheque, as well as the possibility of designating the bearer or not. For the account manager, the possibility of better satisfying the customer's needs by optimising processing time and automating tasks that do not require his or her involvement. The system also optimises processing time and eliminates the risks associated with physical cheques, offering a more secure and efficient alternative. All these operations, of course, take place in a secure environment, a security offered by the blockchain with its use of cryptography and decentralised file system.
Transient, Image‐Guided Gel‐Dissection for Percutaneous Thermal Ablation
Authors: Liu Kathy , Russo Mario , Ellis Joshua S. , Capua John Di , Wu Dufan , Smolinski‐Zhao Sara , Kalva Sanjeeva , Arellano Ronald S. , Irani Zubin , Uppot Raul , Linderman Stephen W. , Gupta Rajiv , Aizenberg Joanna , Srinivasan Shriya , Som Avik 
Published: April 2024

AbstractImage‐guided tumor ablative therapies are mainstay cancer treatment options but often require intra‐procedural protective tissue displacement to reduce the risk of collateral damage to neighboring organs. Standard of care strategies, such as hydrodissection (fluidic injection), are limited by rapid diffusion of fluid and poor retention time, risking injury to adjacent organs, increasing cancer recurrence rates from incomplete tumor ablations, and limiting patient qualification. Herein, a “gel‐dissection” technique is developed, leveraging injectable hydrogels for longer‐lasting, shapeable, and transient tissue separation to empower clinicans with improved ablation operation windows and greater control. A rheological model is designed to understand and tune gel‐dissection parameters. In swine models, gel‐dissection achieves 24 times longer‐lasting tissue separation dynamics compared to saline, with 40% less injected volume. Gel‐dissection achieves anti‐dependent dissection between free‐floating organs in the peritoneal cavity and clinically significant thermal protection, with the potential to expand minimally invasive therapeutic techniques, especially across locoregional therapies including radiation, cryoablation, endoscopy, and surgery.
Bioinspired Flexible Hydrogelation with Programmable Properties for Tactile Sensing
Authors: Wang Yunxiao , Geng Qiang , Lyu Hao , Sun Wuxuepeng , Fan Xinyuan , Ma Kang , Wu Kai , Wang Jinhe , Wang Yancheng , Mei Deqing , Guo Chengchen , Xiu Peng , Pan Dingyi , Tao Kai 
Published: April 2024

AbstractTactile sensing requires integrated detection platforms with distributed and highly sensitive haptic sensing capabilities along with biocompatibility, aiming to replicate the physiological functions of the human skin and empower industrial robotic and prosthetic wearers to detect tactile information. In this regard, short peptide‐based self‐assembled hydrogels show promising potential to act as bioinspired supramolecular substrates for developing tactile sensors showing biocompatibility and biodegradability. However, the intrinsic difficulty to modulate the mechanical properties severely restricts their extensive employment. Herein, by controlling the self‐assembly of 9‐fluorenylmethoxycarbonyl‐modifid diphenylalanine (Fmoc‐FF) through introduction of polyethylene glycol diacrylate (PEGDA), wider nanoribbons are achieved by untwisting from well‐established thinner nanofibers, and the mechanical properties of the supramolecular hydrogels can be enhanced 10‐fold, supplying bioinspired supramolecular encapsulating substrate for tactile sensing. Furthermore, by doping with poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) and 9‐fluorenylmethoxycarbonyl‐modifid 3,4‐dihydroxy‐l‐phenylalanine (Fmoc‐DOPA), the Fmoc‐FF self‐assembled hydrogels can be engineered to be conductive and adhesive, providing bioinspired sensing units and adhesive layer for tactile sensing applications. Therefore, the integration of these modules results in peptide hydrogelation‐based tactile sensors, showing high sensitivity and sustainable responses with intrinsic biocompatibility and biodegradability. The findings establish the feasibility of developing programmable peptide self‐assembly with adjustable features for tactile sensing applications.
Fluorinated Organic Polymers for Cancer Drug Delivery
Authors: Xin Jingrui , Lu Xue , Cao Jimin , Wu Weihui , Liu Qian , Wang Deping , Zhou Xin , Ding Dan 
Published: April 2024

AbstractIn the realm of cancer therapy, the spotlight is on nanoscale pharmaceutical delivery systems, especially polymer‐based nanoparticles, for their enhanced drug dissolution, extended presence in the bloodstream, and precision targeting achieved via surface engineering. Leveraging the amplified permeation and retention phenomenon, these systems concentrate therapeutic agents within tumor tissues. Nonetheless, the hurdles of systemic toxicity, biological barriers, and compatibility with living systems persist. Fluorinated polymers, distinguished by their chemical idiosyncrasies, are poised for extensive biomedical applications, notably in stabilizing drug metabolism, augmenting lipophilicity, and optimizing bioavailability. Material science heralds the advent of fluorinated polymers that, by integrating fluorine atoms, unveil a suite of drug delivery merits: the hydrophobic traits of fluorinated alkyl chains ward off lipid or protein disruption, the carbon–fluorine bond's stability extends the drug's lifecycle in the system, and a lower alkalinity coupled with a diminished ionic charge bolsters the drug's ability to traverse cellular membranes. This comprehensive review delves into the utilization of fluorinated polymers for oncological pharmacotherapy, elucidating their molecular architecture, synthetic pathways, and functional attributes, alongside an exploration of their empirical strengths and the quandaries they encounter in both experimental and clinical settings.
Dual‐Function Electrolyte Additive Design for Long Life Alkaline Zinc Flow Batteries
Authors: Ling Rene , Zhu Zixuan , Peng Kang , Fang Junkai , Zou Wenhao , Li Qixuan , Liu Yulin , Zhu Qinshan , Lin Ning , Xu Tongwen , Yang Zhengjin 
Published: April 2024

AbstractAlkaline zinc‐based flow batteries (AZFBs) have emerged as a promising electrochemical energy storage technology owing to Zn abundance, high safety, and low cost. However, zinc dendrite growth and the formation of dead zinc greatly impede the development of AZFBs. Herein, a dual‐function electrolyte additive strategy is proposed to regulate zinc nucleation and mitigate the hydroxide corrosion of zinc depositions for stable AZFBs. This strategy, as exemplified by urea, introduces an electrolyte additive to coordinate with Zn2+/Zn with proper strength, slowing zinc deposition kinetics to induce uniform nucleation and protecting the deposited zinc surface from attack by hydroxide ions through preferable adsorption. The zincate complexes with urea are identified to be Zn(OH)2(urea)(H2O)2 and Zn2(OH)4(H2O)4(urea), which exhibit slow zinc deposition kinetics, allowing instantaneous nucleation. Calculation results reveal an additional energy barrier of 1.29 eV for the subsequent adsorption of an OH− group when a urea molecule absorbs on the zinc cluster, significantly mitigating the formation of dead zinc. Consequently, prolonged cell cycling of the prototype alkaline zinc‐iron flow battery demonstrates stable operation for over 130 h and an average coulombic efficiency of 98.5%. It is anticipated that this electrolyte additive strategy will pave the way for developing highly stable AZFBs.