bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategic Action Line LI1: Personalised Production
Authors: Monti Marina , Auricchio Ferdinando , Ciarapica Filippo E. , Ghignone Antonello , Fornasiero Rosanna 
Published: June 2024

AbstractThe objective of this chapter is to describe the action line related to Personalised production (LI1). In particular, this chapter proposes research and innovation priorities aimed at promoting industrial systems and models for the efficient manufacture of customized products that can be reconfigured with fast turnarounds to meet specific requests fielded from individual customers or small groups, and that deliver a high level of integration with the customers in order to ensure they become the main actors of the resulting solution. These design and production systems must be conceived to have the capacity to be reconfigured for the manufacture of products that can be required in certain times of emergency (such as health emergencies) or in response to events that can cause a sudden shift in system priorities and require the industrial system to transfer its focus to different categories of products to those usually made. In this action line, it is important to research new supply chain management models and local manufacturing models as well as smart materials.
Strategic Action Line LI2: Industrial Sustainability
Authors: DeMartini Melissa , Colledani Marcello , Picone Nicoletta , Barberio Grazia , Parrini Mauro 
Published: June 2024

AbstractOver the past 20 years, sustainability has become a central issue on the manufacturing and political agenda, and it has recently grown in importance in light of increasingly powerful and devastating climate events. In this chapter, a strategic action line to support companies is proposed to implement industrial sustainability (LI2) by means of strategies, methods and tools to implement sustainable production processes at an environmental, economic and social level, reducing dependence on the external supply of critical production resources or on resources penalized by the laws in force. Priority research actions proposed concern new solutions to reduce noxious or polluting emissions from production processes; methods and techniques for strategic product-process evaluation from a Life-Cycle-Thinking perspective; technologies and processes for the reuse, re-manufacturing and recycling of products, components and materials from used products or maintenance processes; systems and methods for measuring and implementing Sustainable Supply Chains and Closed-Loop Supply Chains.
Strategic Action Line LI3: Factories for Humans
Authors: Dondo Paolo , Viscardi Michele , Viscardi Mauro , Cardinali Fabrizio , Chiabert Paolo , D’Orazio Tiziana , Melchiorri Claudio , Pellicciari Marcello , Peruzzini Margherita , Scandelli Nadia 
Published: June 2024

AbstractThe objective of this chapter is to describe the strategic action line related to the factories for humans (LI3). In particular, this chapter proposes research and innovation priorities aimed at designing and developing new solutions to enhance the role of human resources and their skills, and contribute to their satisfaction and wellbeing; research and experimentation of new technologies for reducing physical exertion, cooperation with advanced support systems, with collaborative robots and with AI-powered technologies; mapping of knowledge generated on the job, especially implicit knowledge, in a way that is compatible with privacy requirements, introducing advantages both on the human wellbeing front—whether the individuals are users, operators or managers—and in terms of business strategies and procedures. In this regard, innovative factories will need to be increasingly inclusive, strongly geared towards the engagement and participation of individuals (users, operators and managers). These models must take a human-centric approach to look into/investigate new technologies and all the dimensions through which the new factory is defined.
Tilted biorthogonal ensembles, Grothendieck random partitions, and determinantal tests
Authors: Gavrilova Svetlana , Petrov Leonid 
Published: June 2024

AbstractWe study probability measures on partitions based on symmetric Grothendieck polynomials. These deformations of Schur polynomials introduced in the K-theory of Grassmannians share many common properties. Our Grothendieck measures are analogs of the Schur measures on partitions introduced by Okounkov (Sel Math 7(1):57–81, 2001). Despite the similarity of determinantal formulas for the probability weights of Schur and Grothendieck measures, we demonstrate that Grothendieck measures are not determinantal point processes. This question is related to the principal minor assignment problem in algebraic geometry, and we employ a determinantal test first obtained by Nanson in 1897 for the $$4\times 4$$

4
×
4

problem. We also propose a procedure for getting Nanson-like determinantal tests for matrices of any size $$n\ge 4$$

n
≥
4

, which appear new for $$n\ge 5$$

n
≥
5

. By placing the Grothendieck measures into a new framework of tilted biorthogonal ensembles generalizing a rich class of determinantal processes introduced by Borodin (Nucl Phys B 536:704–732, 1998), we identify Grothendieck random partitions as a cross-section of a Schur process, a determinantal process in two dimensions. This identification expresses the correlation functions of Grothendieck measures through sums of Fredholm determinants, which are not immediately suitable for asymptotic analysis. A more direct approach allows us to obtain a limit shape result for the Grothendieck random partitions. The limit shape curve is not particularly explicit as it arises as a cross-section of the limit shape surface for the Schur process. The gradient of this surface is expressed through the argument of a complex root of a cubic equation.
The relationship between the attitudes of the use of AI and diversity awareness: comparisons between Japan, the US, Germany, and South Korea
Authors: Ikkatai Yuko , Itatsu Yuko , Hartwig Tilman , Noh Jooeun , Takanashi Naohiro , Yaguchi Yujin , Hayashi Kaori , Yokoyama Hiromi M. 
Published: June 2024

AbstractRecent technological advances have accelerated the use of artificial intelligence (AI) in the world. Public concerns over AI in ethical, legal, and social issues (ELSI) may have been enhanced, but their awareness has not been fully examined between countries and cultures. We created four scenarios regarding the use of AI: “voice,” “recruiting,” “face,” and “immigration,” and compared public concerns in Japan, the US, Germany, and the Republic of Korea (hereafter Korea). Additionally, public ELSI concerns in respect of AI were measured using four items: ethics, tradition, law and social benefit. Respondents with AI knowledge tended to exhibit stronger concern about ELSI in various situations. In terms of law concerns, Japanese respondents displayed greater concerns. In contrast, the US, when compared Japan, expressed a relatively optimistic view of the current law landscape. Regarding social benefits, Korea, compared to Japan, exhibited a more positive outlook, whereas Germany, in comparison to Japan, expressed heightened concerns about it across different scenarios.
Studies on the mechanisms of action of MR33317
Authors: Neumann Joachim , Hesse C. , Yahiaoui S. , Dallemagne P. , Rochais C. , Hofmann B. , Gergs U. 
Published: June 2024

AbstractMR33317 was synthesized as an acetylcholinesterase-inhibitor and an agonist at brain 5-HT4-receptors. MR33317 might be used to treat Morbus Alzheimer. This therapeutic action of MR33317 might be based on MR33317´s dual synergistic activity. We tested the hypothesis that MR33317 also stimulates 5-HT4-receptors in the heart. MR33317 (starting at 10 nM) increased force of contraction and beating rate in isolated atrial preparations from mice with cardiac confined overexpression of the human 5-HT4-serotonin receptor (5-HT4-TG) but was inactive in wild type mouse hearts (WT). Only in the presence of the phosphodiesterase III-inhibitor cilostamide, MR33317 raised force of contraction under isometric conditions in isolated paced (1 Hz) human right atrial preparations (HAP). This increase in force of contraction in human atrium by MR33317 was attenuated by 10 µM tropisetron or GR125487. These data suggest that MR33317 is an agonist at human 5-HT4-serotonin receptors in the human atrium. Clinically, one would predict that MR33317 may lead to atrial fibrillation.
Feminization of the Forehead: A Scoping Literature Review and Cohort Study of Transfeminine Patients
Authors: Khetpal Sumun , Dahoud Fadi , Elias Aura , Sasson Daniel C. , Wolfe Erin M. , Lee Justine C. 
Published: June 2024

Abstract
Background
Facial feminization may be performed to alleviate gender dysphoria among transfeminine patients. The upper third of the face has several characteristics, including hairline shape and position, brow position, and forehead protrusion, that may confer feminine identity. The purpose of this study is to conduct a scoping literature review of techniques performed for forehead feminization and to additionally study clinical outcomes within an institutional cohort.

Methods
A systematic literature review was conducted to review articles that discussed techniques and clinical outcomes associated with procedures performed for feminization of the upper third of the face. A retrospective review of patients undergoing such procedures by the senior author was then conducted. Variables collected included demographic factors, operative details, and postoperative outcomes such as complications, revisions, and re-operations.

Results
Initial review yielded sixty-seven articles. Title and abstract review followed by standardized application of inclusion and exclusion criteria resulted in a total of twenty-two studies for analysis. Priorities of forehead feminization entail frontal bossing reduction, frontonasal angle widening, orbital contouring, brow lifting, and hairline advancement. Eighty-five patients were included for analysis. The majority were of Caucasian race (56%) and had type 3 forehead classification (92%). The average planned setback of the anterior table was 4.12 mm.

Conclusions
The core tenets of the feminization of the forehead lie in the overall creation of a harmonic curvature of the forehead with other facial features. Our multi-pronged analysis presents an updated review of these principles, which may help plastic surgeons in performing procedures to feminize the upper third of the face.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to Table of Contents or online Instructions to Authors www.springer.com/00266.
Gaze-contingent adaptation of VR stereo parameters for cybersickness prevention
Authors: Terzioğlu Berkay , Celikcan Ufuk , Capin Tolga Kurtulus 
Published: June 2024

AbstractExtended exposure to virtual reality displays has been linked to the emergence of cybersickness, characterized by symptoms such as nausea, dizziness, fatigue, and disruptions in eye movements. The main objective of our study is to examine the effects of real-time fine-tuning of stereo parameters and blurriness in virtual reality on the discomfort level of users who are experiencing motion sickness triggered by the display. Our hypothesis proposes that by dynamically correcting the rendering settings, the symptoms of motion sickness can be relieved and the overall VR user experience can be improved. Our methodology commences with a prediction model for the comfort level of the viewer based on their gaze parameters, such as pupil diameter, blink count, gaze position, and fixation duration. We then propose a method to dynamically adapt the stereoscopic rendering parameters by considering the predicted comfort level of the viewer.
Exploring the utility of retinal optical coherence tomography as a biomarker for idiopathic intracranial hypertension: a systematic review
Authors: Prem Senthil Mallika , Anand Saumya , Chakraborty Ranjay , Bordon Jose Estevez , Constable Paul A. , Brown Shannon , Al-Dasooqi Dalia , Simon Simu 
Published: June 2024

AbstractThis study aimed to examine the existing literature that investigated the effectiveness of optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) as a biomarker for idiopathic intracranial hypertension (IIH). Our search was conducted on January 17th, 2024, and included the databases, Medline, Scopus, Embase, Cochrane, Latin American and Caribbean Health Sciences Literature (LILACS), International Standard Randomized Controlled Trial Number (ISRCTN) registry, and the International Clinical Trials Registry Platform (ICTRP). Our final review included 84 articles. In 74 studies, OCT was utilized as the primary ocular imaging method, while OCT-A was employed in two studies including eight studies that utilized both modalities. Overall, the results indicated that IIH patients exhibited significant increases in retinal nerve fiber layer (RNFL) thickness, total retinal and macular thickness, optic nerve head volume, and height, optic disc diameter and area, rim area, and thickness compared to controls. A significant correlation was observed between cerebrospinal fluid (CSF) pressure and OCT parameters including RNFL thickness, total retinal thickness, macular thickness, optic nerve head volume, and optic nerve head height. Interventions aimed at lowering CSF pressure were associated with a substantial improvement in these parameters. Nevertheless, studies comparing peripapillary vessel density using OCT-A between IIH patients and controls yielded conflicting results. Our systematic review supports OCT as a powerful tool to accurately monitor retinal axonal and optic nerve head changes in patients with IIH. Future research is required to determine the utility of OCT-A in IIH.
Treadmill-walking impairs visual function in early glaucoma and elderly controls
Authors: Beyer Rosalie , Al-Nosairy Khaldoon O. , Freitag Constantin , Stolle Francie H. , Behrens Martin , Prabhakaran Gokulraj T. , Thieme Hagen , Schega Lutz , Hoffmann Michael B. 
Published: June 2024

Abstract
Aims
Impaired vision is an additional risk factor in elderly for falls. We investigated the hypothesis that treadmill (TM) walking affects visual function in both healthy elderly and those with early-moderate visual dysfunction due to glaucoma.

Methods
Thirty healthy controls (HC) aged 64–83 years and 18 glaucoma patients (GLA) aged 62–82 years participated in this cross-sectional study. The impact of TM-walking on visual function was assessed binocularly for (i) best-corrected visual acuity (BCVA) with and without crowding effect, (ii) contrast sensitivity (CS), and (iii) and visual field (mean deviation, VF-MD). Visual function was tested while participants were standing or during TM-walking for 2 speed conditions: (i) fast walking at their preferred speed and (ii) walking at a fixed speed of 3.5 km/h.

Results
GLA, most with early-moderate VF loss, performed equally well as HC. Independent of GROUP, an impact of SPEED on visual functions was statistically evident with large statistical effect size for (i) both types of BCVA with a mean loss of 0.02–0.05 logMAR (η2 = 0.41) and (ii) VF-MD with mean loss of 1 dB (η2 = 0.70), but not for CS.

Conclusions
Here, we introduce a paradigm for the assessment of visual function during walking. We provide proof-of-concept that our approach allows for the identification of walking induced visual function loss, i.e., a deterioration of BCVA and VF-sensitivity during TM-walking in both groups. It is therefore of promise for the investigation of the relation of vision impairment and mobility, ultimately the increased frequency of falls in advanced glaucoma.
Uncovering the neural control of laryngeal activity and subglottic pressure in anaesthetized rats: insights from mesencephalic regions
Authors: González-García M. , Carrillo-Franco L. , Morales-Luque C. , Ponce-Velasco M. , Gago B. , Dawid-Milner M. S. , López-González M. V. 
Published: June 2024

AbstractTo assess the possible interactions between the dorsolateral periaqueductal gray matter (dlPAG) and the different domains of the nucleus ambiguus (nA), we have examined the pattern of double-staining c-Fos/FoxP2 protein immunoreactivity (c-Fos-ir/FoxP2-ir) and tyrosine hydroxylase (TH) throughout the rostrocaudal extent of nA in spontaneously breathing anaesthetised male Sprague–Dawley rats during dlPAG electrical stimulation. Activation of the dlPAG elicited a selective increase in c-Fos-ir with an ipsilateral predominance in the somatas of the loose (p < 0.05) and compact formation (p < 0.01) within the nA and confirmed the expression of FoxP2 bilaterally in all the domains within the nA. A second group of experiments was made to examine the importance of the dlPAG in modulating the laryngeal response evoked after electrical or chemical (glutamate) dlPAG stimulations. Both electrical and chemical stimulations evoked a significant decrease in laryngeal resistance (subglottal pressure) (p < 0.001) accompanied with an increase in respiratory rate together with a pressor and tachycardic response. The results of our study contribute to new data on the role of the mesencephalic neuronal circuits in the control mechanisms of subglottic pressure and laryngeal activity.
Assessing volumes of tephra fallout deposits: a simplified method for data scarcity cases
Authors: Sulpizio Roberto , Costa Antonio , Massaro Silvia , Selva Jacopo , Billotta Elisabetta 
Published: June 2024

AbstractA new method for assessing volumes of tephra deposits based on only two thickness data is presented. It is based on the assumptions of elliptical shape for isopachs, a statistical characterization of their eccentricity, and an empirical relationship between their deposit thinning length scale and volumes. The method can be applied if the pair of thickness data are sufficiently distant from the volcano source, with a minimum distance ratio larger than 2. The method was tested against about 40 published volumes, from both equatorial belt and mid-latitude volcanoes. The results are statistically consistent with the published results, demonstrating the usefulness of the method. When applied in forward, the model allowed us to calculate the volume for some important tephra layers in the Mediterranean tephrostratigraphy, providing, for the first time, an assessment of the size of these eruptions or layers.
Feeling of pulsations in artificial arteries with a real time haptic feedback laparoscopic grasper: a validation study
Authors: Vleugels Michel P. H. , Rahimi Masie 
Published: June 2024

Abstract
Introduction
Despite the advancements in technology and organized training for surgeons in laparoscopic surgery, the persistent challenge of not being able to feel the resistance and characteristics of the tissue, including pulsations, remains unmet. A recently developed grasper (Optigrip®) with real time haptic feedback, based on photonic technology, aims to address this issue by restoring the tactile sensation for surgeons. The key question is whether pulsations can be detected and at what minimal size level they become clinical significant.

Methods
To simulate arterial conditions during laparoscopic procedures, four different silicone tubes were created, representing the most prevalent arteries. These tubes were connected to a validated pressure system, generating a natural pulse ranging between 80 and 120 mm Hg. One control tube without pressure was added. The surgeons had to grasp these tubes blindly with the conventional grasper or the haptic feedback grasper in a randomized order. They then indicated whether they felt the pressure or not and the percentage of correct answers was calculated.

Results
The haptic grasper successfully detected 96% of all pulsations, while the conventional grasper could only detect 6%. When considering the size of the arteries, the Optigrip® identified pulsations in 100% the 4 and 5 mm arteries and 92% of the smallest arteries. The conventional grasper was only able to feel the smallest arteries in 8%. These differences were highly significant (p < 0.0001).

Conclusion
This study demonstrated that the newly developed haptic feedback grasper enables detection of arterial pulsations during laparoscopy, filling an important absence in tactile perception within laparoscopic surgery.
Numerical Modelling of the Influence of Tidal Stresses on Fracture Patterns on the Surface of Europa
Authors: Walding John C. , Paluszny Adriana , Zimmerman Robert W. 
Published: June 2024

AbstractJupiter’s satellite Europa is covered by an ice shell exhibiting many surface features, including linear structures called lineae, which in this work are treated as fractures. A three-dimensional finite-element simulator is used to numerically model fracture nucleation, growth, and interaction, assuming the ice is an isotropic, linear elastic medium. Tidal stresses are exerted upon the ice through the Jovian orbital relationship. These stresses are calculated using a closed-form model derived from first principles. The fractures grow in response to stress concentration around their tips, and a damage criterion models the weakening of the ice matrix. Three-dimensional non-planar multiple fracture growth is modelled as a function of geometric multi-modal stress intensity factors computed at the fracture tips. Fracturing is evaluated over multi-scale periods, from days to millions of years, thus capturing multiple tidal effects. Fracture behaviour is modelled across the Europan surface in one domain. The patterns are dense clusters of lineae about the stress maxima with diffuse fracturing in outlying regions. Fractures are also modelled in the vicinity of subsurface meltwater lenses, where fractures form parallel to the surface in contrast to the usual perpendicular orientation. The resultant fracture patterns are qualitatively compared against images from NASA’s Galileo mission. This work contributes to the understanding of Europan lineae by illustrating how they behave in a fracture mechanics framework, and suggests interesting results regarding lineae interaction with meltwater lenses. This work is also a proof of concept for this modelling approach, and will serve as the framework for future work.