bluuebunny/crossref_metadata_2025_split huggingface dataset:
Docência universitária e formação pedagógia: reflexões e perspectivas
Authors: Gomes Edilene Batista , Carvalho Kely Rejane Souza dos Anjos de , Santos Jocyleia Santana dos , Macedo Maria de Lourdes Leoncio , Gomes Darlene Araújo , Carvalho Isabella Cristina Aquino , Leitão Keyliane dos Anjos , Carvalho Junior Ciro Ferreira de 
Published: February 2025

A docência universitária tem sido objeto de estudo em diversas pesquisas realizadas no contexto atual. Diante disso, o presente estudo visa contribuir com reflexões a respeito da formação pedagógica de professores para a docência universitária. Considera-se como aspectos bastante relevantes as discussões acerca dos objetivos e concepções que orientam a formação de professores. A partir de então, questionou-se: como são constituídos os saberes profissionais dos professores universitários? Qual o papel da universidade na formação pedagógica dos professores? E, para responder a esses questionamentos, realizou-se uma pesquisa bibliográfica com a finalidade de delinear os processos que orientam o fazer pedagógico do professor do ensino superior. O estudo em questão foi baseado em autores como Masetto (1998, 2020), Cunha (1998, 2005, 2008), Pimenta e Anastasiou (2014), dentre outros que discutem a temática. Por meio da pesquisa realizada, constatou-se que os saberes docentes são constituídos por diversos meios, como programas de formação continuada, estágio de docência, valorização profissional, e que a universidade é um fator relevante no processo de formação pedagógica do professor, pois, ao oferecer programas de formação, esses se tornarão subsídios para o desenvolvimento profissional.
THE GENDER-SPECIFIC SURVIVAL RATES AMONG PEOPLE LIVING WITH HIV ON ANTIRETROVIRAL THERAPY IN THE KYRGYZ REPUBLIC
Authors: Shabdan k.Z. , Omonov I. , Djumagulova A. , Abdyraeva B. 
Published: February 2025

In the Kyrgyz Republic for the entire period as of 12/31/2023, 13 289 people were living with HIV infection. Testing, treatment, and viral load suppression cascades are 70 - 79 - 90. Treatment approaches and low immune status affect the survival rate of PLHIV receiving ART. The purpose of this study is to conduct a survival analysis in HIV-infected patients on ART as well as to evaluate the efficacy of the treatment depending on gender. Data of 13 289 registered cases in the Kyrgyz Republic among patients of 18 years and older on ART was processed. An analysis of viral loads, the level of CD4 and death rates was carried out at different periods of duration of ART. The duration of ART influences survival rates positively, the latter being higher in women. Women achieve virological effectiveness at the start of ART faster than men. Virological and immunological effectiveness among women on ART is higher than among men. Timely initiated ART increases survival rates, especially among women.
В Кыргызской Республике за весь период по состоянию на 31.12.2023 с ВИЧ-инфекцией проживало 13 289 человек. Каскады тестирования, лечения и подавления вирусной нагрузки составляют 70–79–90. Целью исследования является проведение анализа выживаемости ВИЧ-инфицированных пациентов на АРТ, а также оценка эффективности лечения в зависимости от пола. Использованы данные 13 289 зарегистрированных случаев по состоянию на 31.12.2023 года среди пациентов 18 лет и старше на АРТ. Анализ вирусной нагрузки, уровня CD4 клеток и смертности проводился в разные периоды длительности АРТ. Продолжительность АРТ положительно влияет на выживаемость, причем последняя выше у женщин. Иммунологическая и вирусологическая эффективность у женщин, получающих АРТ, выше, чем у мужчин. Своевременно начатая АРТ повышает выживаемость, особенно среди женщин.
Кыргыз Республикасында 12/31/2023 күнгө ылайык 13 289 адам АИВ инфекциясы менен жашайт. Тестирлөө, дарылоо жана вирустук басмырлоо көрсөткүчү 70-79-90. Изилдөөнүн максаты - АРТдагы АИВ менен жашап кетүү көрсөткүчтөрүн анализдөө жана жынысына жараша дарылоонун натыйжалуулугун эсептөө. Кыргыз Республикасынын АРТ алган 18 жаштан жогорку 13 289 кишинин маалыматы колдонулду. Вирустук басмырлоо, CD4 клеткаларынын деңгээли жана өлүм көрсөткүчтөрүнун анализи АРТ процессинин ар башка мөөнөттөрүндө жүргүзүлдү. АРТ мөөнөтү жашап кетүү көрсөткүчүнө жакшы таасир этет, өзгөчө аялдарда. АРТ алгандардын ичинен аялдарда иммундук жана вирустук эффективдүүлүк эркектерге караганда жогору. Убагында башталган АРТ жашап кетүү көрсөткүчүн жакшыртат, өзгөчө аялдарда.
Sociological Sierra Leonean Biology: A Discernment of Communal Mortal Growth and Social Demeanor
Authors: Bangura Mohamed 
Published: February 2025

Sociological and biological developments are broadly identified as considerations of communal mortal growth, wellness, and socio-economic achievements over social existence cycle, but Sierra Leoneans awareness of the fundamental routes and procedures stays restricted. To handle this sociological crack, the sociological researcher interpret the sociobiology way as one that theorizes the sociological and biological as collectively forming, and that outlines on clones and approaches from the neuroscience and communal or sociology. By importing biology into the Sierra Leonean sociology, sociologists can enlighten tools via which psychosocial, socioeconomic, and other communal elements form mortal Sierra Leonean social growth. Immunology is a social biology, and functional initiatives can consequently recognize manners of sociological spaces that are damaging, as well as gainful, with regard social health. By accompanying behavioral psychology thoughts and sociological inquiry strategies to biology and biomedicine, the sociological researcher inspire a philosophical switch that focuses contextual and social elements as significant causations of mortal biology and social health. The sociobiology avenues also reinforces the significance of the existence social cycle, as evaluations of both sociological and biological characteristics around mortal social growth over time, and across procreations, are required to accomplish a complete comprehension of bodily and social health. The sociological researcher concludes with a concise discourse of the inquiry, which expose the worth of a sociobiology highway to know the avenues connecting social hierarchy, health, and biology over Sierra Leonean social existence and social cycle.
Evaluation of the Outcome of the Middle Turbinate Medialization (Fixation to Nasal Septum) by Various Surgical Technique
Authors: Alhaideri Ali Jameel , Al-Hassani Jaafer Mohammed Kadhim , Alkhazraji Zeena Jamal 
Published: February 2025

The primary objectives and essential aspects of ESS are to facilitate the proper drainage and ventilation of the afflicted groups of paranasal sinuses. The size and location of the middle turbinate directly impact the drainage of all paranasal sinuses.
A prospective study has been conducted in the otolaryngology department at Al-Imamain Al-kadhmain teaching hospital from September 2021 to May 2023 on 180 selected patients, divided into three groups; each contains sixty patients with the following specific surgical intervention: group I: medialization of the middle turbinate only, group II: medialization of the middle turbinate with fixation to the nasal septum, and group III: medialization of the middle turbinate with fixation to the nasal septum by trans-septal sutures. Postoperatively, follow-up was done weekly during the 1st month and every 2 weeks during the 2nd month by assessing symptom improvement and nasal endoscopic findings. The findings showed that one hundred (55.6%) patients were males and eighty (44.4%) patients were females. The patients' ages varied from 20 to 48 years (mean ± SD = (33.45 ± 8.95) years). Post-operative improvement of presenting symptoms in order of sequence from higher to lower were as follows: nasal obstructions (74%), nasal discharge (74%), facial pain (70%), smell disorders (61%), and headache (53%).
The current study concluded that the technique of middle turbinate medialization promotes effective drainage and ventilation, allowing for long-term monitoring and post-surgical suction clearing. Although it has its limits, the suturing method of the middle turbinate (conchopexy) is an efficient technique for preventing lateralization of the middle turbinate. This method has demonstrated superior overall outcomes when compared to iatrogenic adhesion (Bolgerization).
Utilización de Educaplay en la enseñanza del inglés como lengua extranjera
Authors: Rincón Zambrano Rodrigo Alexander , Amén Mora Paúl Geovanny , Santos Mera Lisbeth Madelayne , Solórzano Álava Wilter Leonel 
Published: February 2025

Este trabajo analiza el uso de Educaplay como herramienta innovadora para enseñar inglés. Educaplay es una plataforma online que permite crear actividades educativas interactivas como crucigramas, juegos de memoria y tests, haciendo el aprendizaje más atractivo. Las ventajas de usar Educaplay en clases de inglés incluyen una mejor retención de vocabulario y gramática, mayor motivación estudiantil a través de la gamificación, y la posibilidad de adaptar las actividades a distintos niveles. La plataforma también ofrece retroalimentación inmediata, reforzando el aprendizaje. Se presentarán ejemplos prácticos de actividades en Educaplay para desarrollar diversas habilidades lingüísticas, así como estrategias para incorporar la plataforma en la planificación de clases y evaluación. Se propone Educaplay como un recurso valioso para profesores de inglés, combinando interactividad, motivación y adaptabilidad para mejorar la enseñanza y el aprendizaje. El presente trabajo es resultado del proyecto de investigactión titulado "Perfeccionamiento de las prácticas pedagógicas en las instituciones educativas de la zona sur de Manabí" y también contriubuye como parte de los resultado del proyecto de vinculación titulado "Tareas dirigidas y apoyo Psicopedagógico para fortalecer el aprendizaje de los alumnos en la Educación básica Pública de Jipijapa Fase II 2024"
Racial and Ethnic and Rural Variations in Access to Primary Care for Veterans Following the MISSION Act
Authors: Rosen Amy K. , Beilstein-Wedel Erin , Shwartz Michael , Davila Heather , Gurewich Deborah 
Published: June 2024

ImportanceThe 2018 Veterans Affairs Maintaining Internal Systems and Strengthening Integrated Outside Networks (VA MISSION) Act was implemented to increase timely access to care by expanding veterans’ opportunities to receive Veterans Affairs (VA)–purchased care in the community (community care [CC]). Because health equity is a major VA priority, it is important to know whether Black and Hispanic veterans compared with White veterans experienced equitable access to primary care within the VA MISSION Act.ObjectiveTo examine whether utilization of and wait times for primary care differed between Black and Hispanic veterans compared with White veterans in rural and urban areas after the implementation of the VA MISSION Act.Design, Setting, and ParticipantsThis cross-sectional study used VA and CC outpatient and consult data from the VA’s Corporate Data Warehouse for fiscal years 2021 to 2022 (October 1, 2020, to September 30, 2022). Separate fixed-effects multivariable models were run to predict CC utilization and wait times. Each model was run twice, once comparing Black and White veterans and then comparing Hispanic and White veterans. Adjusted risk ratios (ARRs) were calculated for Black and Hispanic veterans compared with White veterans within rurality status for both outcomes.Main Outcomes and MeasuresVA and CC primary care utilization as measured by primary care visits (utilization cohort); VA and CC primary care access as measured by mean wait times (access cohort).ResultsA total of 5 046 087 veterans (994 517 [19.7%] Black, 390 870 [7.7%] Hispanic, and 3 660 700 [72.6%] White individuals) used primary care from fiscal years 2021 to 2022. Utilization increased for all 3 racial and ethnicity groups, more so in CC than VA primary care. ARRs were significantly less than 1 regardless of rurality status, indicating Black and Hispanic veterans compared with White veterans were less likely to utilize CC for primary care. There were 468 246 primary care consultations during the study period. The overall mean (SD) wait time was 33.3 (32.4) days. Despite decreases in wait times over time, primary care wait times remained longer in CC than in VA. Black veterans compared with White veterans had significantly longer wait times in CC (ARRs &amp;gt;1) but significantly shorter wait times in VA (ARRS &amp;lt;1) regardless of rurality status in VA and CC. CC wait times for Hispanic veterans compared with White veterans were longer in rural areas only and in VA rural and urban areas (ARRs &amp;gt;1).Conclusion and RelevanceThe results of this cross-sectional study suggest that additional research should explore the determinants and implications of utilization differences among Black and Hispanic veterans compared with White veterans. Efforts to promote equitable primary care access for all veterans are needed so that policy changes can be more effective in ensuring timely access to care for all veterans.
A Self-Guided Internet-Based Intervention for the Reduction of Gambling Symptoms
Authors: Rolvien Lara , Buddeberg Lisa , Gehlenborg Josefine , Borsutzky Swantje , Moritz Steffen 
Published: June 2024

ImportanceMost individuals with problem gambling or gambling disorder remain untreated due to barriers to treatment. Limited research exists on alternative treatments.ObjectiveTo investigate the efficacy of a self-guided internet-based intervention for individuals with gambling problems and to identify potential outcome moderators.Design, Setting, and ParticipantsThis single-center randomized clinical trial was conducted from July 13, 2021, to December 31, 2022, at the University Medical Center Hamburg-Eppendorf. Participants were recruited across Germany for 2 assessments (before intervention [t0] and 6 weeks after intervention [t1]). Eligible participants were individuals aged 18 to 75 years with gambling problems, internet access, German proficiency, and willingness to participate in 2 online assessments.InterventionThe self-guided internet-based intervention was based on cognitive behavioral therapy, metacognitive training, acceptance and commitment therapy, and motivational interviewing.Main Outcome and MeasuresThe primary outcome was change in gambling-related thoughts and behavior as measured with the pathological gambling adaption of the Yale-Brown Obsessive-Compulsive Scale. Secondary outcomes were change in depressive symptoms, gambling severity, gambling-specific dysfunctional thoughts, attitudes toward online interventions, treatment expectations, and patient satisfaction.ResultsA total of 243 participants (154 [63.4%] male; mean [SD] age, 34.73 [10.33] years) were randomized to an intervention group (n = 119) that gained access to a self-guided internet-based intervention during 6 weeks or a wait-listed control group (n = 124). Completion at t1 was high (191 [78.6%]). Results showed a significantly greater reduction in gambling-related thoughts and behavior (mean difference, −3.35; 95% CI, −4.79 to −1.91; P &amp;lt; .001; Cohen d = 0.59), depressive symptoms (mean difference, −1.05; 95% CI, −1.87 to −0.22; P = .01; Cohen d = 0.33), and gambling severity (mean difference, −1.46; 95% CI, −2.37 to −0.54; P = .002; Cohen d = 0.40) but not in gambling-specific dysfunctional thoughts (mean difference, −1.62; 95% CI, −3.40 to 0.15; P = .07; Cohen d = 0.23) favoring the intervention group. Individuals in the intervention group who had a positive treatment expectation and more severe gambling-specific dysfunctional thoughts and gambling symptoms benefited more on the primary outcome relative to the control group.Conclusions and RelevanceIn this randomized clinical trial, the effectiveness of a self-guided internet-based intervention for individuals with self-reported problematic gambling behavior was demonstrated when measured 6 weeks after start of the intervention. The study’s findings are particularly relevant given the increasing need for accessible and scalable solutions to address problematic gambling.Trial Registrationbfarm.de Identifier: DRKS00024840
Advances in Vascular Diagnostics using Magnetic Particle Imaging (MPI) for Blood Circulation Assessment
Authors: Pacheco Marisa O , Gerzenshtein Isabelle K , Stoppel Whitney L , Rinaldi‐Ramos Carlos M 
Published: June 2024

AbstractRapid and accurate assessment of conditions characterized by altered blood flow, cardiac blood pooling, or internal bleeding is crucial for diagnosing and treating various clinical conditions. While widely used imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound offer unique diagnostic advantages, they fall short for specific indications due to limited penetration depth and prolonged acquisition times. Magnetic particle imaging (MPI), an emerging tracer‐based technique, holds promise for blood circulation assessments, potentially overcoming existing limitations with reduction in background signals and high temporal and spatial resolution, below the millimeter scale. Successful imaging of blood pooling and impaired flow necessitates tracers with diverse circulation half‐lives optimized for MPI signal generation. Recent MPI tracers show potential in imaging cardiovascular complications, vascular perforations, ischemia, and stroke. The impressive temporal resolution and penetration depth also position MPI as an excellent modality for real‐time vessel perfusion imaging via functional MPI (fMPI). This review summarizes advancements in optimized MPI tracers for imaging blood circulation and analyzes the current state of pre‐clinical applications. This work discusses perspectives on standardization required to transition MPI from a research endeavor to clinical implementation and explore additional clinical indications that may benefit from the unique capabilities of MPI.
Effective Self‐Powered Semimetal TaTe2 Photodetector with the Thermal Localization Photothermoelectric Effect from Ultraviolet to Mid‐Infrared Range
Authors: Xia Cong , Yu Tong , Liu Jianying , Li Xin , Wang Jiajia , Ma Shihui , Yang Guangsai , Qiu Hailong , Hu Zhanggui , Ye Ning , Wang Jiyang , Wu Yicheng 
Published: June 2024

AbstractUltra‐broadband photodetectors based on semimetal crystals have recently become popular because of their gapless band structures. In particular, semimetal crystals have large carrier mobility or high Seebeck coefficient; this almost eliminates the possibility of using semimetal crystals as photodetectors. In addition, a larger temperature gradient can cause photocurrent generation based on the photothermoelectric effect. Surprisingly, the TaTe2 crystal has a huge absorption coefficient (≈104 cm−1), a minimal specific heat (≈0.172 J g−1 K−1), and a low thermal conductivity (0.3 W m−1 K−1), which is beneficial for generating a high photothermal conversion efficiency of 30.2%, despite its small Seebeck coefficient, and achieving a large temperature gradient occurs for the heat generated by external illumination. Herein, the possibility of photoresponse based on the TaTe2 detector is explored, which has a low carrier mobility (≈10 cm2 V−1 s−1) and a small Seebeck coefficient (≈7.1 µV K−1). The self‐powered TaTe2 photodetector can also provide a competitive photoresponse range from 355 to 2715 nm and exhibit a maximum responsivity of 1.1 mA W−1 with a detectivity of 4.7 × 108 Jones at 455 nm. This study provides a new design scheme and operating mechanism for semimetal photodetectors and enriches semimetal crystal photodetectors.
Stabilization of Quantum‐Confined Anisotropic CsPbI3 Nanoplatelets by Solid‐Phase Metal Iodide Crude Reaction for Color‐Pure Red Emission
Authors: Solari Simon F. , Wieczorek Alexander , Marcato Tommaso , Wörle Michael , Krumeich Frank , Li Yen‐Ting , Chiu Yu‐Cheng , Siol Sebastian , Shivarudraiah Sunil B. , Shih Chih‐Jen 
Published: June 2024

AbstractQuantum‐confined CsPbI3 perovskite nanoplatelets (NPLs) are highly desirable for optoelectronic applications owing to their anisotropic electronic properties that substantially boost the light outcoupling efficiency in light‐emitting diodes (LEDs). However, the structural instability of the emissive CsPbI3 phases makes it degrade rapidly to the non‐emissive δ‐phase under ambient conditions. Here, the study presents a synthetic approach to produce spectrally stable CsPbI3 nanoplatelets (NPLs) through solid‐phase crude reactions with metal iodide powders, MI2 (M2+ = Mn2+ or Zn2+). The synthesized NPLs exhibit narrow and color‐pure red emission with high photoluminescence (PL) quantum yields (QYs, ηPL) of up to 85%. Systematic investigations into the surface chemistry of NPLs reveal that metal iodide treatment stabilizes anisotropic CsPbI3 NPLs via surface passivation with metal and halide ions, substantially hindering from the formation of non‐emissive yellow phase. The anisotropic NPLs display signatures of spontaneous self‐assembly in spin‐casted films, which yield strong emission anisotropy, with up to 82% of the transition dipoles being horizontally oriented with respect to the substrate, as revealed by the back focal plane (BFP) imaging. The results presented here shed light on solid‐phase approaches for the preparation of quantum‐confined nanocrystals (NCs) with desirable geometry, which boost the light outcoupling efficiency in LEDs.
Assembly of Functionalized 3,4‐Fused Tricyclic Benzosultams via Radical‐Promoted Cascade Reactions
Authors: Reddy Chada Raji , Kumari Ankita , Sagar Banoth Karuna , Patil Amol D. 
Published: June 2024

AbstractA tandem oxidative radical functionalization/annulation of N‐acryloyl amino saccharin is disclosed. This strategy allows the facile construction of diversely functionalized 3,4‐fused tricyclic benzosultams that previously have not been reported. A wide range of functionalities were installed through the formation of C−C, C−S and C−P bond enabled by the respective radicals.
Bacterial Influence on Pharmacokinetics of Tacrolimus and Sulfasalazine through Regulation of Host Metabolism
Authors: Cooper David A. , Bhushan Abhinav 
Published: June 2024

AbstractThe unpredictable oral bioavailability of established drugs like tacrolimus and sulfasalazine presents a significant clinical challenge. This variability can lead to either toxicity or insufficient therapeutic effect. It is known that alterations in drug transporters and metabolic enzymes influence drug bioavailability. Recent evidence suggests that the indirect metabolism by gut microbes could influence transporters and enzymes which can affect the bioavailability of oral drugs. In this study, the pharmacokinetics of tacrolimus and sulfasalazine are modeled under varying host colonic conditions induced by the bacteria E. coli Nissle 1917 and Bifidobacterium adolescentis. Insight is provided into the sensitivity of pharmacokinetics to the bacterial influence on expression of intestinal drug transporters and cytochrome p450 enzymes. Our findings demonstrate that bacterial modulation reduces tacrolimus peak blood concentration compared to healthy renal transplant patients. Conversely, bacterial presence leads to a two‐fold increase in sulfasalazine's peak plasma concentration compared to healthy subjects. These results suggest that incorporating the gut bacteria's influence on colonic transporters and enzymes can improve the explanation of pharmacokinetic variability. This approach has the potential to refine pharmacokinetic models and ultimately address the challenge of variable oral drug bioavailability.