bluuebunny/crossref_metadata_2025_split huggingface dataset:
association between maternal oral bacteria with early childhood caries development in their children
Authors: Singh Shweta , Singh Neerja , S Sahana 
Published: June 2024

Objective: The objective of this prospective study was to investigate the association between maternal oral bacteria and the development of early childhood caries (ECC) in their children over a two-year period.
Methods: A cohort of mothers and their children was recruited during the prenatal period. Maternal oral samples were collected to assess the presence and abundance of specific cariogenic bacteria, including Streptococcus mutans and Lactobacillus species, using polymerase chain reaction (PCR) techniques. The children were followed up at regular intervals from birth until two years of age. Oral examinations were conducted to assess the presence and severity of ECC. Statistical analyses was performed to determine the association between maternal oral bacteria and ECC development in their children.
Results: The study included 98 mother-child pairs, with an average follow-up period of 24 months. The results demonstrated a significant association between maternal oral bacteria and ECC development in their children. Maternal colonization of cariogenic bacteria, particularly S. mutans, was found to be a strong predictor of ECC development in their offspring, even after adjusting for confounding factors such as maternal oral hygiene, socioeconomic status, and child's diet. Higher levels of S. mutans in maternal oral samples were associated with an increased risk of ECC in children at two years of age.
Conclusion: This prospective study provides evidence for an association between maternal oral bacteria and the development of early childhood caries in their children over a two-year period. Maternal colonization of cariogenic bacteria, especially Streptococcus mutans, was found to be a significant risk factor for ECC development. These findings highlight the importance of maternal oral health and the need for preventive measures targeting maternal oral bacteria to reduce the transmission and subsequent development of ECC in children. Early interventions, including oral hygiene education and preventive strategies, should be implemented to promote maternal oral health and improve oral health outcomes in children.
Comparative evaluation of efficacy of 2% lidocaine and 4% Articaine in paediatric patients during Needle insertion by Conventional and Alternative technique of local Anasthesia
Authors: Kulkarni Parimala , Sharma Rajesh , Bhat Manohar 
Published: June 2024

Background: Local anesthesia is an essential part of many dental procedures, particularly in pediatric patients who may be fearful or anxious during treatment. Two of the most commonly used local anesthetics are 2% lidocaine and 4% articaine, but there is ongoing debate about which one is more effective. Additionally, the technique used for administering local anesthesia can also impact pain perception during needle insertion. This topic aims to compare the efficacy of 2% lidocaine and 4% articaine, as well as to evaluate the pain perception of pediatric patients during needle insertion using both conventional and alternative techniques of local anesthesia.
Methodology: A total of 180 pediatric patients were included in the study, and they were randomly assigned to receive either 2% lidocaine or 4% articaine using either conventional or alternative techniques. The study included pediatric patients aged 4-12 years, who required dental treatment involving local anesthesia assigned to the following groups. Group 1: 2% lidocaine with conventional technique of local anesthesia; Group 2: 2% lidocaine with alternative technique of local anesthesia; Group 3: 4% articaine with conventional technique of local anesthesia; Group 4: 4% articaine with alternative technique of local anesthesia. Outcome assessed were onset and duration of anesthesia.
Results: The results showed that the use of 4% articaine was more effective in increasing the duration of anesthesia and a faster onset than 2% lidocaine, regardless of the technique used. Additionally, the alternative technique was found to be less painful than the conventional technique.
Conclusion: This study provides important insights into the use of local anesthesia in pediatric patients and highlights the potential benefits of using 4% articaine and alternative techniques for reducing pain and discomfort during needle insertion.
Passive Leg Movement as a Diagnostic Tool for Distinguishing Healthy Individuals from Those with Obstructive Sleep Apnea
Authors: Alyousif Zakaria A , Black Craig P , Wambold Suzanne , Khuder Sadik A. , Scheuermann Barry W 
Published: June 2024

Background – Obstructive Sleep Apnea (OSA) is linked with endothelial dysfunction, posing a significant risk for cardiovascular diseases. The non-invasive assessment of endothelial function through passive leg movement (PLM) offers a novel diagnostic avenue. This study explores PLM's efficacy in differentiating between healthy individuals and those with OSA, alongside evaluating the impact of oral vitamin C on endothelial function within these groups.

Materials and Methods:
The study enrolled 26 male subjects, divided equally into healthy and OSA groups. PLM was performed using an isokinetic machine to assess femoral artery blood flow (FBF) and blood velocities (FBVs) via Doppler ultrasound. Subjects consumed 1000mg of oral vitamin C, with measurements repeated post-consumption. Data analysis involved repeated measures ANOVA to evaluate the diagnostic capability of PLM and the effect of vitamin C on FBF responses.
Results:
A significant difference in FBF was observed between OSA and healthy groups (healthy: 162.1 ml/min, OSA: 76.6 ml/min; p < 0.05), confirming PLM's diagnostic potential. However, vitamin C administration did not significantly alter FBF responses in OSA patients (pre-vitamin C: 76.6 ml/min, post-vitamin C: 79.9 ml/min; p > 0.05), challenging the anticipated benefits of oral vitamin C on endothelial function.
Conclusion:
PLM effectively distinguishes between healthy individuals and those with OSA, highlighting its diagnostic utility. Nonetheless, oral vitamin C did not improve endothelial dysfunction in OSA patients, suggesting the need for further research on alternative administration methods or dosages.
The Effects of High Intensity Interval Training (HIIT) on Asthmatic Adult Males
Authors: Alyousif Zakaria A , Black Craig P , Wambold Suzanne , Nawras Mohamad , Scheuermann Barry W 
Published: June 2024

Background – This study explored the effects of High-Intensity Interval Training (HIIT) on pulmonary function, exercise tolerance, and fractional concentration of exhaled nitric oxide (FeNO) in asthmatic and healthy adults. FeNO levels, associated with lung inflammation, are a diagnostic tool for asthma treatment, making this study significant for understanding HIIT's impact on asthma management.

Materials and Methods:
Fourteen male subjects (7 asthmatic, 7 healthy) participated in a two-week HIIT protocol. Pulmonary function was assessed using peak expiratory flow (PEF), forced vital capacity (FVC), and the FEV1/FVC ratio. FeNO was measured with a NIOX portable device. Subjects underwent a progressive exercise test on a cycle ergometer to determine peak oxygen uptake (VO2 peak), CO2 output (VCO2 peak), ventilation (VE), and time to exhaustion (TTE). HIIT sessions included warm-ups, 10 x 60-second high-intensity bouts with 60-second recovery intervals, and cool-downs. Intensity targeted 75% peak work rate (WR) for asthmatics and 80% for controls.
Results:
Significant differences were observed between groups in FeNO, VO2 peak, TTE, and peak WR, with no significant changes in pulmonary function measures. Pre-HIIT, asthmatics showed a mean FeNO of 28 ± 2 ppb compared to controls at 18 ± 1 ppb, with post-HIIT levels remaining stable. TTE and peak WR improved in both groups post-HIIT, indicating enhanced exercise tolerance and performance capacity. Specifically, asthmatics showed an increase in TTE from 691 ± 40 s to 781 ± 41 s and in peak WR from 175 ± 13 W to 203 ± 14 W.
Conclusion:
HIIT was well-tolerated by asthmatic subjects, leading to improved exercise tolerance, higher ventilation, CO2 output, and work rate performance, without significant changes in pulmonary function or FeNO levels. These findings suggest that HIIT can be a safe and effective exercise intervention for asthmatic individuals to enhance exercise performance.
Peculiar unión
Authors: Núñez García Itzel Carolina 
Published: June 2024

En la naturaleza, principalmente en las plantas, existen pequeños seres conocidos como hongos endófitos. Estos amigos casi invisibles, ayudan a las plantas a ser fuertes y saludables. ¿Quieres saber más? Te invito a seguir leyendo y aprendiendo sobre los hongos endófitos.
MANAJEMEN RESIKO PENYAKIT TIDAK MENULAR (PTM) PADA MASYARAKAT MARGINAL DI YOGYAKARTA
Authors: Permina* Yullya , Intening Vivi Retno , Sudarta I Wayan 
Published: June 2024

Penyakit Tidak Menular merupakan tantangan kesehatan utama di seluruh dunia, yang sering kali disebabkan oleh faktor-faktor yang dapat dimodifikasi seperti gaya hidup dan lingkungan. PTM menjadi masalah kesehatan masyarakat yang serius karena memiliki tingkat morbiditas (kesakitan) dan mortalitas (kematian) yang tinggi di seluruh dunia. Beberapa contoh PTM termasuk penyakit hipertensi, diabetes melitus, stroke, dan penyakit pernapasan kronis. kegiatan pengabdian masyarakat tentang penyuluhan manajemen resiko PTM, screening kesehatan serta senam untuk peningkatan kesehatan belum pernah didapatkan. Tujuan dari pengabdian ini adalah mengingkatkan pengetahuan tentang manajemen resiko Penyakit Tidak Menular pada masyarakat maarginal di Yogyakarta. Metode pelaksanaan dengan melakukan screening kesehatan pengukuran tekanan darah dan gula dara sesaat (GDS), ceramah, senam dan diskusi. Hasil nilai sebelum dilakukan edukasi adalah 18 dan sesudah edukasi 26. Pengethauan yang dimiliki oleh manusia merupakan upaya mencari kebenaran dan solusi untuk masalah adalah bagian dari kodrat manusia. Ini mencerminkan sifat dasar manusia yang selalu ingin tahu, belajar, dan berkembang Kesimpulannya adalah kegiatan pengabdian ini dapat berjalan dengan baik, Masyarakat antusias mengikuti setiap kegiatan yang telah dilaksanakan, semakin memahami tentang bagaimana melakukan manajemen resiko PTM
RELEVANSI TEORI, IDEOLOGI DAN TEOLOGI DALAM FILSAFAT EKONOMI ISLAM
Authors: Ajeung Syilva Syara Noor Silmi Sudrajat  , Ai Reni Ratnasari1  
Published: June 2024

Abstract:

The relationship between theory, ideology and theology in Islamic economic philosophy creates a strong foundation for building an economic system based on Islamic values. This creates hope for achieving a balance between economic growth and social justice.
This journal examines the complex relationship between theory, ideology and theology in the context of Islamic economic philosophy. Islamic economic philosophy is a scientific discipline that combines economic principles with the teachings of the Islamic religion. In this research, the author uses a historical approach, a comparative or comparison approach and the researcher also uses a conceptual approach. This is done to dig deeper into the relationship between theory, ideology and theology of Islamic economic philosophy. This paper seeks to explain how Islamic economic theory is not only based on conventional economic principles, but is also reflected in deep Islamic ideology and theology.

Keywords: Islamic Economics, Economic Theory, Economic Ideology, Islamic Theology.

Abstrak:

Keterkaitan antara teori, ideologi, dan teologi dalam filsafat ekonomi Islam menciptakan landasan yang kuat untuk membangun sistem ekonomi yang berlandaskan pada nilai-nilai Islam. Hal ini menciptakan harapan untuk mencapai keseimbangan antara pertumbuhan ekonomi dan keadilan sosial.
Jurnal ini mengkaji keterkaitan yang kompleks antara teori, ideologi, dan teologi dalam konteks filsafat ekonomi Islam. Filsafat ekonomi Islam adalah disiplin ilmu yang menggabungkan prinsip ekonomi dengan ajaran-ajaran agama Islam. Dalam penelitian ini penulis menggunakan pendekatan historis, pendekatan komparatif atau perbandingan dan juga peneliti gunakan pendekatan konseptual hal ini dilakukan untuk menggali lebih dalam dan mengenai keterkaitan antara teori, ideologi dan teologi filsafat ekonomi islam. Tulisan ini berusaha untuk menjelaskan bagaimana teori ekonomi Islam tidak hanya didasarkan pada prinsip-prinsip ekonomi konvensional, tetapi juga tercermin dalam ideologi dan teologi Islam yang mendalam.

Kata Kunci : Ekonomi Islam, Teori Ekonomi, Ideologi Ekonomi, Teologi Islam.
Associations of age at diagnosis of breast cancer with incident myocardial infarction and heart failure: A prospective cohort study
Authors: Liang Jie , Pan Yang , Zhang Wenya , Gao Darui , Wang Yongqian , Xie Wuxiang , Zheng Fanfan 
Published: June 2024

Background:The associations of age at diagnosis of breast cancer with incident myocardial infarction (MI) and heart failure (HF) remain unexamined. Addressing this problem could promote understanding of the cardiovascular impact of breast cancer.Methods:Data were obtained from the UK Biobank. Information on the diagnosis of breast cancer, MI, and HF was collected at baseline and follow-ups (median = 12.8 years). The propensity score matching method and Cox proportional hazards models were employed.Results:A total of 251,277 female participants (mean age: 56.8 ± 8.0 years), of whom 16,241 had breast cancer, were included. Among breast cancer participants, younger age at diagnosis (per 10-year decrease) was significantly associated with elevated risks of MI (hazard ratio [HR] = 1.36, 95% confidence interval [CI] 1.19–1.56, p<0.001) and HF (HR = 1.31, 95% CI 1.18–1.46, p<0.001). After propensity score matching, breast cancer patients with younger diagnosis age had significantly higher risks of MI and HF than controls without breast cancer.Conclusions:Younger age at diagnosis of breast cancer was associated with higher risks of incident MI and HF, underscoring the necessity to pay additional attention to the cardiovascular health of breast cancer patients diagnosed at younger age to conduct timely interventions to attenuate the subsequent risks of incident cardiovascular diseases.Funding:This study was supported by grants from the National Natural Science Foundation of China (82373665 and 81974490), the Nonprofit Central Research Institute Fund of Chinese Academy of Medical Sciences (2021-RC330-001), and the 2022 China Medical Board-open competition research grant (22-466).
Instandhaltung und statische Sicherung der Stadtpfarrkirche von Pfaffenhofen an der Ilm
Authors: Rehm Jörg , Barthel Rainer , Maus Helmut 
Published: May 2012

AbstractÜber dem Hauptschiff der Stadtpfarrkirche St. Johannes Baptist in Pfaffenhofen an der Ilm befindet sich ein über 520 Jahre altes Dachwerk. Das Sparrendach mit zweifach stehendem Stuhl entstand im Zuge des spätgotischen Ausbaus der Kirche am Ende des 15. Jahrhunderts und wurde bei der Erweiterung der Kirche um 1910 nach Westen ergänzt. Der Dachstuhl über dem Chorbereich wurde bereits vor 1900 erneuert. Durch Feuchteeinwirkung im Bereich der Fußpunkte war der älteste Teil des Dachstuhls in seiner Tragfähigkeit stark beeinträchtigt. Weiterhin wurden Verformungen und komplexe Rissbilder an den aufgehenden Wänden und den Gewölben festgestellt, die in einer sorgfältigen Schadensaufnahme dokumentiert wurden. Der Kirchenraum mit seiner frühbarocken Stuckausstattung stellte hohe Anforderungen an das Instandsetzungskonzept, bei dem es gleichermaßen um die Behebung lokaler Schädigungen wie um die Sicherung der aufgehenden Wände im Ganzen ging. Alle Maßnahmen konnten mit dem Ziel der größtmöglichen Erhaltung historischer Substanz geplant und ausgeführt werden. In einem weiteren Bauabschnitt ist noch die Teilunterfangung des Chores vorgesehen. Erst nach dieser Maßnahme wird die Innenrestaurierung in Angriff genommen.Repair and static saving of the main church of Pfaffenhofen/Ilm, GermanyThe main nave of St. Johannes Baptist in Pfaffenhofen a. d. Ilm still possesses its historic roof structure from the late 15th century. The couple roof with its main trusses was erected during the building's late gothic extension. its western part as added in 1910 after the historic model; the roof above the sanctuary was rebuild in around 1900. A series of damage made a thorough restoration of the church inevitable: the roof trusses' base joints were decayed, and the walls and vaults showed cracks and deformations. In a thorough survey, the damage was systematically recorded and its causes analyzed. The preservation of the church's valuable interior its 17th century stucco made special care during the restoration necessary: all measures were planned and carried out with a special focus on the conservation of historic substance. The underpinning of the sanctuary will follow in the next construction phase; the restoration of the interior is intended as the final step.
Kolkbildung an komplexen Gründungsstrukturen für Offshore‐Windenergieanlagen
Authors: Stahlmann Arne , Schlurmann Torsten 
Published: May 2012

AbstractBei der Gründung von Offshore‐Strukturen kommt es oftmals zu einer Ausbildung von Kolken um die Gründungsbauwerke, die einen erheblichen Einfluss auf die Standsicherheit und Gebrauchstauglichkeit der Anlagen haben können. Für komplexe Strukturen liegen derzeit noch keine ausreichenden Erkenntnisse zur Kolkbildung für die Bemessung vor. Im Zuge umfassender Untersuchungen werden daher die Kolkphänomene um komplexe Gründungen wie den Tripod detailliert erforscht und analysiert, um so physikalische Prozesse und Einflussgrößen genauer beschreiben zu können. Als Untersuchungsinstrument dienen hierbei Messdaten aus klein‐ und großskaligen physikalischen Modellversuchen, numerische CFD‐Simulationen sowie Naturmessdaten, aus denen sich insgesamt eine Variabilität der Kolkbildung in Abhängigkeit der Randbedingungs‐ und Strukturparameter mit größten Kolktiefen unterhalb der Tripod‐Struktur abzeichnen.Investigations on scour at tripod foundationsRegarding offshore constructions, in most cases scouring occurs around the foundation, considerably influencing the stability and usability of the structure. There is still a lack in knowledge of scour progression for complex foundations at present, which is however necessary for the dimensioning of the construction. Therefore comprehensive investigations are carried out, mainly focusing on the scouring phenomena at complex foundations like the tripod, in order to describe physical processes and influencing factors. The investigation method consists of a unique combination of small and large scale physical modeling, numerical CFD simulations and in‐situ measured scour data, which generally show a variability of scouring depending on load boundary conditions and structural parameters with largest scours measured under the tripod structure.
Nachbildung der Hydroabrasionsbeanspruchung im Laborversuch
Authors: Helbig Ulf , Horlacher Hans.‐B. , Stamm Jürgen , Bellmann Claudia , Butler Marko , Mechtcherine Viktor 
Published: May 2012

AbstractDer Oberflächenverschleiß von Wasserbauwerken resultiert zu einem hohen Maße aus hydroabrasiver Belastung infolge Überströmung mit feststoffbehaftetem Wasser. Hierbei spielen auf der Einwirkseite die Fließverhältnisse, die Feststoffart, ‐form und ‐zusammensetzung sowie die Zeitdauer der Exposition eine maßgebliche Rolle. Als schwierig erweisen sich unter anderem eine realitätsnahe versuchstechnische Nachbildung sowie ein Vergleich bzw. eine Übertragbarkeit der Verschleißzustände zwischen Modellversuch und Natur. Die experimentellen Untersuchungen zum Einfluss einiger maßgebender Parameter auf die Betonschädigung wurden im ersten Teil des Aufsatzes beschrieben. In diesem, zweiten Teil des Aufsatzes wird ein auf der Basis der gewonnenen Erkenntnisse und Daten entwickelter Korrelationsansatz vorgestellt, mit dem es nun möglich ist, unter Berücksichtigung der Schwere‐ und Turbulenzverhältnisse sowie der mittleren Korndurchmesser gegenseitige Beziehungen zwischen verschiedenen Hydroabrasionsregimen aufzustellen und eine modellbasierte Prognose des Betonverschleißes vorzunehmen.Simulation of hydro‐abrasion loading in the laboratory. Part 2 – correlation of wear and approaches of predictionThe wear of hydraulic structures is to a great extent caused by hydroabrasive loading. The degree of exposure to such wearing action mostly depends on the flowing waters characteristics, the type, shape and composition of the transported solid phase (sediments) as well as the duration of the exposure. It is also difficult to simulate the hydroabrasive process realistically under laboratory conditions, so that different states of wear as observed in experiments could be compared to or transformed into the real hydroabrasive situations in the practice of construction. The first part of this paper presented the results of own experimental investigations on the effects of various decisive parameters on the concrete degradation due to hydroabrasion. Based on the attained comprehension and data a correlation approach was developed, which enables to estimate the concrete wear under consideration of gravitation and turbulence conditions as well as mean grain diameter. This work is presented in this second part of the paper.
Erneuerung des Rheinhafens Bendorf
Authors: Dormann Michael , Herbort Johannes 
Published: May 2012

AbstractIm Dezember 2010 begannen die Bauarbeiten zur Erneuerung der Umschlagufer im Rheinhafen Bendorf. Im Rahmen dieser Baumaßnahme werden die über 80 bis 110 Jahre alten Uferwände des Hafens auf einer Länge von 430 m durch eine neue vorgesetzte Stahlspundwand ersetzt, weiterhin werden zwei Gefahrgutliegeplätze für Tankschiffe um weitere Anlegedalben verlängert und mit zusätzlichen Landgängen ausgestattet. Die Hafensohle wird auf einer Fläche von ca. 65000 m2 vertieft und damit an den bereits erfolgten Mittelrheinausbau angepasst. Mit Geländeauffüllungen bis zu 4 m Höhe wird eine neue ca. 12000 m2 große hochwassersichere Lager‐ und Umschlagfläche geschaffen. Die neuen Betriebsflächen erhalten eine Oberflächenbefestigung aus Verbundsteinpflaster und ein neues Entwässerungssystem einschließlich eines Regenrückhalte‐ und Absetzbeckens. Sämtliche Arbeiten müssen unter laufendem Hafenbetrieb erfolgen. Inzwischen sind der erste Bauabschnitt der neuen Uferspundwand einschließlich der hochwassersicheren Betriebsfläche sowie die Verlängerung der Gefahrgutliegeplätze fertiggestellt, in der ersten Jahreshälfte 2012 werden sämtliche Arbeiten abgeschlossen sein. Nach der Fertigstellung steht der Rheinhafen Bendorf GmbH ein moderner und leistungsfähiger Binnenhafen mit deutlich verbesserten Bedingungen für die Berufsschifffahrt und die Umschlagbetriebe zur Verfügung.Renewal of the Rhine‐Port Bendorf – Modernization of an over 100‐year old inland portIn December the construction work for the renewal of the handling quays in the Rhine‐Port Bendorf started. The 80 – 110 years old bank walls will be replaced by a steel sheet piling with a length of 430 m. Also two berths for tankers will be extended by further mooring dolphins and equipped with additional gangways. A 65000 m2 area of the harbour floor will be deepened and thus adapted to the improvement of the Middle Rhine. A new flood‐proof storage and handling area of about 12000 m2 will be created by means of landfills up to 4 m height. These new areas will get a surface with interlocking paving stones and a new drainage system including a rain detention and settling basin. The total work has to be carried out during full harbour operation. Meanwhile the first construction phase of the new sheet piling including the flood‐proof area and the extension of the berths are finished, by the end of June 2012 the total work will be completed. Upon completion the Rhine‐Port Bendorf will be a modern and efficient inland harbour with clearly improved conditions for the ship's crews and the handling companies.