bluuebunny/crossref_metadata_2025_split huggingface dataset:
White electroluminescent single‐polymer achieved by incorporating three polyfluorene blue arms into a star‐shaped orange core
Authors: Chen Lei , Li Pengcheng , Tong Hui , Xie Zhiyuan , Wang Lixiang , Jing Xiabin , Wang Fosong 
Published: April 2012

AbstractA series of star‐like dopant/host single‐polymer systems with a D‐A type star‐shaped orange core and three blue polyfluorene arms were designed and synthesized. Through tuning the doping concentration of the orange core and thermal annealing treatment of white polymer light‐emitting diodes based on them, highly efficient white electroluminescence has been achieved. A typical single‐layer device (ITO/PEDOT:PSS/polymer/Ca/Al) realized pure white emission with a luminous efficiency of 16.62 cd A−1, an external quantum efficiency of 6.28% and CIE coordinates of (0.33, 0.36) for S‐WP‐002TPB3 containing 0.02 mol % orange core. The high efficiency of the devices could be mainly attributed to the suppressed concentration quenching of the dopant units, more efficient energy transfer from polymer host to orange dopant and thermal annealing‐induced α‐phase polyfluorene (PF) self‐dopant in amorphous PF host. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Manipulation of the bioactivity of glucose oxidase via raft‐controlled surface modification
Authors: Luo Xiong , Liu Jingquan , Liu Guozhen , Wang Rui , Liu Zhen , Li Aihua 
Published: April 2012

AbstractIn this article, poly[poly(ethyleneglycol) acrylate] (polyPEG‐A) with mercaptothiazoline ester terminal group was synthesized directly by reversible addition fragmentation chain transfer (RAFT) polymerization using a mercaptothiazoline ester functional RAFT agent. The functional polyPEG‐A was then conjugated to glucose oxidase (GOx) via surface‐tethered amino groups through covalent amide coupling. Sorensenformaltitration assay revealed that GOx retained ∼14 free amino groups available for covalent modification. The conjugation reaction turned out to be efficient and mild. Colorimetric method was applied to evaluate the enzymatic activity of native GOx and its derivatives by introducing another enzyme, horseradish peroxidase. The modified GOx with polymeric chains exhibited reduced enzymatic activity toward the catalytical oxidation of glucose, but with significantly increased thermal stability and elongated lifetime. When GOx was modified with polyPEG‐A [molecular weight (MW), 45,000; polydispersity index, 1.12] the enzymatic activity was decreased to 37 U/mg, only 29% left. However, when incubated at 25 °C the modified GOx still retained 9.6% of its original bioactivity after 60 days, whereas the native GOx only lived for 29 days. The more polymer chains or the longer polymer chain attached, the more reduction of the enzymatic activity resulted, however, the longer the lifetime of the enzyme obtained. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Relevance of local parallel theory to the linear stability of laminar separation bubbles
Authors: Diwan Sourabh S. , Ramesh O. N. 
Published: April 2012

AbstractLaminar separation bubbles are thought to be highly non-parallel, and hence global stability studies start from this premise. However, experimentalists have always realized that the flow is more parallel than is commonly believed, for pressure-gradient-induced bubbles, and this is why linear parallel stability theory has been successful in describing their early stages of transition. The present experimental/numerical study re-examines this important issue and finds that the base flow in such a separation bubble becomes nearly parallel due to a strong-interaction process between the separated boundary layer and the outer potential flow. The so-called dead-air region or the region of constant pressure is a simple consequence of this strong interaction. We use triple-deck theory to qualitatively explain these features. Next, the implications of global analysis for the linear stability of separation bubbles are considered. In particular we show that in the initial portion of the bubble, where the flow is nearly parallel, local stability analysis is sufficient to capture the essential physics. It appears that the real utility of the global analysis is perhaps in the rear portion of the bubble, where the flow is highly non-parallel, and where the secondary/nonlinear instability stages are likely to dominate the dynamics.
Direct numerical simulation of a 30R long turbulent pipe flow at R+ = 685: large- and very large-scale motions
Authors: Wu Xiaohua , Baltzer J. R. , Adrian R. J. 
Published: April 2012

AbstractFully developed incompressible turbulent pipe flow at Reynolds number ${\mathit{Re}}_{D} = 24\hspace{0.167em} 580$ (based on bulk velocity) and Kármán number ${R}^{+ } = 684. 8$ is simulated in a periodic domain with a length of $30$ pipe radii $R$. While single-point statistics match closely with experimental measurements, questions have been raised of whether streamwise energy spectra calculated from spatial data agree with the well-known bimodal spectrum shape in premultiplied spectra produced by experiments using Taylor’s hypothesis. The simulation supports the importance of large- and very large-scale motions (VLSMs, with streamwise wavelengths exceeding $3R$). Wavenumber spectral analysis shows evidence of a weak peak or flat region associated with VLSMs, independent of Taylor’s hypothesis, and comparisons with experimental spectra are consistent with recent findings (del Álamo & Jiménez, J. Fluid Mech., vol. 640, 2009, pp. 5–26) that the long-wavelength streamwise velocity energy peak is overestimated when Taylor’s hypothesis is used. Yet, the spectrum behaviour retains otherwise similar properties to those documented based on experiment. The spectra also reveal the importance of motions of long streamwise length to the $uu$ energy and $uv$ Reynolds stress and support the general conclusions regarding these quantities formed using experimental measurements. Space–time correlations demonstrate that low-level correlations involving very large scales persist over $40R/ {U}_{\mathit{bulk}} $ in time and indicate that these motions convect at approximately the bulk velocity, including within the region approaching the wall. These very large streamwise motions are also observed to accelerate the flow near the wall based on force spectra, whereas smaller scales tend to decelerate the mean streamwise flow profile, in accordance with the behaviour observed in net force spectra of prior experiments. Net force spectra are resolved for the first time in the buffer layer and reveal an unexpectedly complex structure.
Acute and chronic watercress supplementation attenuates exercise-induced peripheral mononuclear cell DNA damage and lipid peroxidation
Authors: Fogarty Mark C. , Hughes Ciara M. , Burke George , Brown John C. , Davison Gareth W. 
Published: April 2012

Pharmacological antioxidant vitamins have previously been investigated for a prophylactic effect against exercise-induced oxidative stress. However, large doses are often required and may lead to a state of pro-oxidation and oxidative damage. Watercress contains an array of nutritional compounds such as β-carotene and α-tocopherol which may increase protection against exercise-induced oxidative stress. The present randomised controlled investigation was designed to test the hypothesis that acute (consumption 2 h before exercise) and chronic (8 weeks consumption) watercress supplementation can attenuate exercise-induced oxidative stress. A total of ten apparently healthy male subjects (age 23 (sd4) years, stature 179 (sd10) cm and body mass 74 (sd15) kg) were recruited to complete the 8-week chronic watercress intervention period (and then 8 weeks of control, with no ingestion) of the experiment before crossing over in order to compete the single-dose acute phase (with control, no ingestion). Blood samples were taken at baseline (pre-supplementation), at rest (pre-exercise) and following exercise. Each subject completed an incremental exercise test to volitional exhaustion following chronic and acute watercress supplementation or control. The main findings show an exercise-induced increase in DNA damage and lipid peroxidation over both acute and chronic control supplementation phases (P< 0·05v.supplementation), while acute and chronic watercress attenuated DNA damage and lipid peroxidation and decreased H2O2accumulation following exhaustive exercise (P< 0·05v.control). A marked increase in the main lipid-soluble antioxidants (α-tocopherol, γ-tocopherol and xanthophyll) was observed following watercress supplementation (P< 0·05v.control) in both experimental phases. These findings suggest that short- and long-term watercress ingestion has potential antioxidant effects against exercise-induced DNA damage and lipid peroxidation.
Cloning and characterization of three chemosensory proteins from Spodoptera exigua and effects of gene silencing on female survival and reproduction
Authors: Gong L. , Luo Q. , Rizwan-ul-Haq M. , Hu M.-Y. 
Published: April 2012

AbstractInsect chemosensory proteins (CSPs) are supposed to transport hydrophobic chemicals to receptors on sensory neurons. However, CSPs are broadly expressed in various insect tissues, suggesting their involvement in the physiological processes beyond chemoreception. So, the exact physiological roles of CSPs in insects still need to be unraveled. In this study, three full-length of CSP genes from Spodoptera exigua have been cloned and characterized. The deduced amino acid sequences of SexiCSP1, SexiCSP2 and SexiCSP3 revealed open reading frames of 128, 128 and 126 amino acids, respectively, with four conserved cysteine residues. The expression patterns of the three SexiCSPs were further investigated by real-time PCR. Three SexiCSPs were expressed in antennae, heads, legs, wings, thoraxes, abdomens, testes and ovaries, with the highest expression level in female and male antennae. Furthermore, all three SexiCSPs mRNA were distributed extensively in the tested development stages with the highest expression level in pupae. RNAi-based gene silencing study resulted in a dramatic reduction of corresponding mRNA in female S. exigua after injection with dsRNA of all three SexiCSPs. Consequentially, 42.5% of mortalities, 68.3% (compare to DEPC water injected control) and 71.4% (compare to uninjected control) oviposition inhibition, and significantly effected egg hatching were observed in the female S. exigua injected with dsSexiCSP3 as compared to control treatments. On the other hand, dsSexiCSP1 and dsSexiCSP2 injected female adults did not show effects on survival and reproduction. Our study confirms the utility of RNAi approach to functional characterization of CSP genes in S. exigua and provides a starting point for further studies on female survival and reproduction in this insect. It also reveals the potential pest controlling method, as insect behavior regulation agent that disrupts the expression of chemosensory proteins.
Playing Ball in Greek Antiquity
Authors: O'SULLIVAN LARA 
Published: April 2012

Among the plethora of minor players whose names intrude briefly into the historical record of the age of Alexander the Great is Aristonicus of Carystus. A member of Alexander's entourage, he clearly attained some standing in his own right, and at least some of that renown derived, it seems, from his prowess as a ball-player. Thus one of the interlocutors in Athenaeus' Deipnosophistai reports of his honouring at Athens (1.19a) thatἈριστόνικον τὸν Καρύστιον, τὸν Ἀλεξάνδρου σϕαιριστήν, Ἀθηναῖοι πολίτην ἐποιήσαντο διὰ τὴν τέχνην καὶ ἀνδριάντα ἀνέστησαν.The Athenians made Aristonicus the Carystian, Alexander's ball-player, a citizen of their city on account of his skill, and they erected a statue to him.
Does Issue Linkage Work? Evidence from European Alliance Negotiations, 1860 to 1945
Authors: Poast Paul 
Published: April 2012

AbstractThough scholars widely claim that issue linkage—the simultaneous negotiation of multiple issues for joint settlement—can help states conclude international agreements, there exist some notable skeptics. Resolving this debate requires empirical evidence. However, beyond a few case studies, there exists no direct and systematic evidence that issue linkages actually increase the probability of agreement. I address this lack of direct and systematic evidence by combing original data on failed alliance negotiations with data from the Alliance Treaty Obligations and Provisions (ATOP) database. Using matching techniques, I find that, for alliance negotiations between 1860 to 1945, offers of trade linkage did substantially increase the probability of agreement. Besides confirming issue linkage's ability to help clinch an agreement, this article's research design and evidence have far-reaching implications for the study of negotiations and alliances. The research design illustrates the value of considering the “dogs that didn't bark” as it identifies both successful andfailednegotiations. The article's evidence explains the high rate of alliance compliance identified by previous scholars and highlights a need to rethink the alliance formation process.
Origins of the Russian Antarctic expedition: 1819–1821
Authors: Tammiksaar Erki , Kiik Tarmo 
Published: April 2012

ABSTRACTIn 1819, the Russian government launched two expeditions: the first squadron of two ships departed to explore the southern polar areas, and the second set out for the northern polar areas. The expedition to the southern polar areas took place under the command of Fabian Gottlieb von Bellingshausen. Up to the present day, very little information is available, from the Russian literature, about the initiator and main goals of the expedition. At the same time, the travels and main results of the expedition have been widely popularised, but not necessarily accurately, in Russian as well as in English. On the basis of recently discovered documents, this article attempts to establish who the initiator of these Russian expeditions was, how the expeditions were prepared, and whether the main tasks of the expeditions were realised. The conclusion is that Jean-Baptiste Prevost de Sansac, Marquis de Traversay was the initiator of the Russian Antarctic expedition, not the Russian navigators Adam Johan von Krusenstern, Otto von Kotzebue, Gavrila A. Sarychev or Vasilii M. Golovnin as stated in Soviet publications. The real aim of the expedition was to discover the Antarctic continent which would have added glory to de Traversay as well as to Emperor Alexander I and, in a wider sense, also to the Russian empire. All dates are given according to the old style calendar. The difference with the new style calendar is 12 days.
Depressive symptoms are associated with weight gain among women
Authors: Sutin A. R. , Zonderman A. B. 
Published: April 2012

BackgroundMany studies have linked depression and obesity; few have more than two assessments of depressive symptoms and adiposity to address the potential bidirectional relationship between adiposity and depressive symptoms from young adulthood through old age. We tested whether baseline depressive symptoms are associated with changes in weight, whether baseline adiposity is associated with changes in depressive symptoms, and whether these associations vary by sex.MethodParticipants (n=2251; 47% female) were from the Baltimore Longitudinal Study of Aging (BLSA). Using hierarchical linear modeling (HLM) on 30 years of data, the trajectory of adiposity and depressive symptoms over adulthood was estimated from >10 000 observations (mean=4.5 assessments per participant) of body mass index (BMI; kg/m2), waist circumference and hip circumference and >10 000 observations (mean=4.5 assessments per participant) of the Center for Epidemiological Studies Depression Scale (CES-D). Baseline depressive symptoms and adiposity were then tested as predictors of the trajectory of adiposity and depressive symptoms respectively. Additional analyses tested for sex-specific associations.ResultsSex moderated the association between depressive symptoms and weight gain such that women who experienced depressed affect had greater increases in BMI (binteraction=0.12, s.e.=0.04), waist (binteraction=0.22, s.e.=0.10) and hip circumference (binteraction=0.20, s.e.=0.07) across the adult lifespan, controlling for relevant demographic and behavioral covariates. Baseline adiposity was unrelated to the trajectory of depressive symptoms (median b=0.00) for both sexes.ConclusionsWomen who experience symptoms of depression tend to gain more weight across adulthood than men who experience such symptoms. Whether an individual was normal weight or overweight was unrelated to changes in depressive symptoms across adulthood.
The causal relationships between neurocognition, social cognition and functional outcome over time in schizophrenia: a latent difference score approach
Authors: Hoe M. , Nakagami E. , Green M. F. , Brekke J. S. 
Published: April 2012

BackgroundSocial cognition has been identified as a significant construct for schizophrenia research with relevance to diagnosis, assessment, treatment and functional outcome. However, social cognition has not been clearly understood in terms of its relationships with neurocognition and functional outcomes. The present study sought to examine the empirical independence of social cognition and neurocognition; to investigate the possible causal structure among social cognition, neurocognition and psychosocial functioning.MethodThe sample consists of 130 individuals diagnosed with schizophrenia. All participants were recruited as they were admitted to four community-based psychosocial rehabilitation programs. Social cognition, neurocognition and psychosocial functioning were measured at baseline and 12 months. The empirical independence of social cognition and neurocognition was tested using confirmatory factor analysis (CFA) and the possible causal structure among social cognition, neurocognition and psychosocial functioning was investigated using latent difference score (LDS) analysis.ResultsA two-factor model of social cognition and neurocognition fit the data very well, indicating the empirical independence of social cognition, whereas the longitudinal CFA results show that the empirical independence of neurocognition and social cognition is maintained over time. The results of the LDS analysis support a causal model that indicates that neurocognition underlies and is causally primary to social cognition, and that neurocognition and social cognition are causally primary to functional outcome.ConclusionsSocial cognition and neurocognition could have independent and distinct upward causal effects on functional outcome. It is also suggested that the approaches for remediation of neurocognition and social cognition might need to be distinct.
LOVE/SICK: A CONVERSATION WITH ANGELA ELLSWORTH
Authors: Takemoto Tina 
Published: April 2012

Editor's Note: In this previously unpublished conversation from 2007, Tina Takemoto and Angela Ellsworth discuss their collaboration during a period when Ellsworth was diagnosed with and underwent treatment for Hodgkin's lymphoma. For those compelling collaborations, the artists confronted the effects of diagnosis and prognosis on the experience of embodiment, the gendered and racialized practices of medical care, and the limits of empathy in communicating across illness/health. In this conversation, Takemoto and Ellsworth reconvene after a crisis in their collaborations to work through the complications that arose for each in their attempts to stage and manage performances that would make a difference in the treatment of cancer. This interview was conducted in New York City on 16 September 2007.
Pulse oximetry home monitoring in infants with single-ventricle physiology and a surgical shunt as the only source of pulmonary blood flow
Authors: Öhman Annika , Strömvall-Larsson Eva , Nilsson Boris , Mellander Mats 
Published: April 2012

AbstractBackgroundShunt occlusion is a major cause of death in children with single ventricle. We evaluated whether one daily measurement of oxygen saturation at home could detect life-threatening shunt dysfunction.MethodsA total of 28 infants were included. Parents were instructed to measure saturation once daily and if less than or equal to 70% repeat the measurement. Home monitoring was defined as positive when a patient was admitted to Queen Silvia Children's Hospital because of saturation less than or equal to 70% on repeated measurement at home. A shunt complication was defined as arterial desaturation and a narrowing of the shunt that resulted in an intervention to relieve the obstruction or in death. Parents’ attitude towards the method was investigated using a questionnaire.ResultsA shunt complication occurred out of hospital eight times in eight patients. Home monitoring was positive in five out of eight patients. In two patients, home monitoring was probably life saving; in one of them, the shunt was replaced the same day and the other had an emergency balloon dilatation of the shunt. In three out of eight patients, home monitoring was negative; one had an earlier stage II and survived, but two died suddenly at home from thrombotic shunt occlusion. On seven occasions in three patients home monitoring was positive but there was no shunt complication. The method was well accepted by the parents according to the results of the questionnaire.ConclusionHome monitoring of oxygen saturation has the potential to detect some of the life-threatening shunt obstructions between stages I and II in infants with single-ventricle physiology.
QP and QS in the upper mantle beneath the Iberian peninsula from recordings of the very deep Granada earthquake of April 11, 2010
Authors: Mancilla F. , Del Pezzo E. , Stich D. , Morales J. , Ibañez J. , Bianco F. 
Published: April 2012

Granada (Southern Spain) is a place of rare and enigmatic very deep focus earthquakes, the last one on April 11, 2010, with magnitude of 6.3 and depth of 620 km. We use regional broadband recordings to estimate QP and QSin the mantle for frequencies between 0.25 and 8 Hz, computing the spectra of the direct P‐ and S‐waves with their early P‐ and S coda. We use the spectral decay method, constraining crustalQ to values given in the literature. We obtain robust estimates of QP in 6 frequency bands (0.25, 0.5,1, 2, 4 and 8 Hz) and of QS in 4 bands (0.25, 0.5,1, 2 Hz). QP in the mantle ranges from 13 at 0.25 Hz to 346 at 8 Hz and QS from 59 at 0.25 to 183 at 2 Hz. The frequency dependence is well fitted by Q = Q0fα with α equal to 0.6 for QS and 1.0 for QP, and Q0 equal to 109 for QS and 63 for QP. The QP/QS ratio is less than 1. These are extreme values within the ranges of mantle Q, QP/QS and αvalues reported in the literature, indicating strong scattering attenuation and absence of melt. We propose that such values, rather than being an exception, may approximate the average upper mantle, with solid olivine composition and small‐scale heterogeneity.