bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of In Utero Wi‐Fi Exposure on the Pre‐ and Postnatal Development of Rats
Authors: Poulletier de Gannes Florence , Haro Emmanuelle , Hurtier Annabelle , Taxile Murielle , Athane Axel , Ait‐Aissa Saliha , Masuda Hiroshi , Percherncier Yann , Ruffié Gilles , Billaudel Bernard , Dufour Philippe , Veyret Bernard , Lagroye Isabelle 
Published: February 2012

BACKGROUNDThe increase in exposure to the Wireless Fidelity (Wi‐Fi) wireless communication signal has raised public health concerns especially for young people. Animal studies looking at the effects of early life and prenatal exposure to this source of electromagnetic fields, in the radiofrequency (RF) range, on development and behavior have been considered as high priority research needs by the World Health Organization.METHODSFor the first time, our study assessed the effects of in utero exposure to a 2450 MHz Wi‐Fi signal (2 hr/day, 6 days/week for 18 days) on pregnant rats and their pups. Three levels in terms of whole‐body specific absorption rate were used: 0.08, 0.4, and 4 W/kg. The prenatal study on fetuses delivered by caesarean (P20) concerned five females/group. The dams and their offspring were observed for 28 days after delivery (15 females/group).RESULTSFor all test conditions, no abnormalities were noted in the pregnant rats and no significant signs of toxicity were observed in the pre‐ and postnatal development of the pups, even at the highest level of 4 W/kg.CONCLUSIONSIn the present study, no teratogenic effect of repeated exposures to the Wi‐Fi wireless communication signal was demonstrated even at the highest level of 4 W/kg. The results from this screening study aimed at investigating Wi‐Fi effects, strengthen the previous conclusions that teratology and development studies have not detected any noxious effects of exposures to mobile telephony‐related RF fields at exposure levels below standard limits.
Improvement of light emission of Mn‐doped Zn2SiO4 phosphors with sodium
Authors: Hu Yi , Yang Jen‐Pu , Liu Jiun‐Shing 
Published: February 2012

ABSTRACTMn‐doped willemite (Zn2SiO4:Mn) green phosphor were synthesized by sol–gel technology. The effect of the addition of sodium, as in the composition Zn(1.92 – X) NaXMn0.08SiO4, on the emission behavior was studied. FT–IR and EPR results revealed that sodium ion is incorporated into the lattice and results in the formation of isolated Mn2+ and Mn–Mn pairs. The maximum emission intensity of the sample under ultraviolet (UV) excitation occurred at the sodium concentration of x = ~0.03. The green emission at about 525 nm is assigned to Mn2+–Mn2+ pair centres on nearest neighbour Zn sites. The highest intensity of the green emission for x = ~0.03 is well close to the highest concentration of the Mn2+–Mn2+ pair. Copyright © 2012 John Wiley & Sons, Ltd.
Determination of arecoline in areca nut based on field amplification in capillary electrophoresis coupled with electrochemiluminescence detection
Authors: Xiang Qian , Gao Ying , Han Bingyan , Li Jing , Xu Yunhong , Yin Jianyuan 
Published: February 2012

ABSTRACTA sensitive capillary electrophoresis–electrochemiluminescence (CE–ECL) assay with an ionic liquid (IL) was developed for the determination of arecoline in areca nut. The IL, 1‐butyl‐3‐methylimidazolium tetrafluoroborate (BMImBF4), was an effective additive improved not only the separation selectivity but also the detection sensitivity of the analyte. BMImBF4 in the separation electrolyte made the resistance of the separation buffer much lower than that of the sample solution, which resulted in an enhanced field amplified electrokinetic injection CE. ECL intensity of arecoline is about two times higher than that of the analyte with phosphate–IL buffer system. Resolution between arecoline and other unknown compounds in real samples was improved. Under the optimized conditions (ECL detection at 1.2 V, 16 kV separation voltage, 20 mmol/L phosphate with 10 mmol/L BMImBF4 buffer at pH 7.50, 5 mmol/L Ru(bpy)32+ and 50 mmol/L phosphate buffer in the detection reservoir), a detection limit of 5 × 10–9 mol/L for arecoline was obtained. Relative standard deviations of the ECL intensity and the migration time were 4.51% and 0.72% for arecoline. This method was successfully applied to determination of the amount of arecoline in areca nut within 450 s. Copyright © 2012 John Wiley & Sons, Ltd.
Effect of Roux-en-Y gastric bypass on testosterone and prostate-specific antigen
Authors: Woodard G , Ahmed S , Podelski V , Hernandez-Boussard T , Presti J , Morton J M 
Published: February 2012

AbstractBackgroundObese men have lower serum levels of testosterone, dehydroepiandrosterone (DHEA) and prostate-specific antigen (PSA), but an increased risk of dying from prostate cancer. The aim of this study was to examine the effect of surgically induced weight loss on serum testosterone, DHEA and PSA levels in obese men.MethodsConsecutive men undergoing Roux-en-Y gastric bypass (RYGB) participated in a prospective, longitudinal study. Main outcomes were changes were body mass index (BMI), percentage excess weight loss, serum levels of testosterone, DHEA and PSA, PSA mass and plasma volume, measured before operation and 3, 6 and 12 months later.ResultsIn 64 patients, mean BMI fell from 48·2 kg/m2 before operation to 39·2, 35·6 and 32·4 kg/m2 at 3, 6 and 12 months after RYGB. Testosterone levels rose significantly from 259 ng/dl to 386, 452 and 520 ng/dl respectively. Serum PSA levels increased significantly from 0·51 ng/ml to 0·67 ng/ml at 12 months. There were no significant changes in DHEA or PSA mass.ConclusionRYGB normalizes the serum testosterone level. PSA levels increase with weight loss and may be inversely correlated with changes in plasma volume, indicating that PSA levels may be artificially low in obese men owing to haemodilution.
Compatibility of the HINTEGRA prostheses with Korean ankles as evaluated on the basis of cadaveric measurements
Authors: Eun Sang Soo , Lee Woo‐Chun , Lee Sang‐Ho , Paik Doo Jin , Hwang Young‐Il 
Published: February 2012

AbstractThe purpose of this study was to obtain anatomical measurements of the distal tibia and talus of Korean ankles and to evaluate, based on those measurements, the compatibility of the HINTEGRA prostheses in the context of total ankle replacement (TAR). We measured the length, width, height, and angles of the distal tibia and talus of 51 cadavers and compared these measurements with the corresponding dimensions of the HINTEGRA prostheses. The male ankles were larger than the female ones as was expected, but their overall shapes did not differ, which fact validates use of the prostheses irrespective of patients' sex. The dimensions of the talus itself did not differ significantly from those previously reported for American whites and blacks and South African whites. This might suggest a possibility that the HINTEGRA prostheses, being used in these countries, would be compatible to Korean ankles, too. In fact, the length range of the talar components was generally compatible with those derived from cadaveric measurements of the trochlea. However, the widths of the tibial and talar components were not completely compatible to Korean ankles. Above all, the length of the large‐sized tibial components was much longer than the largest ankles, which would confine the choice of prosthesis mainly to small‐sized ones for arthroplasty in Korea. Even though these prostheses are currently used, some modifications are needed to extend their usability in Korea, such as shortening and width/length ratio adjustment of the tibial component, and of the talar component accordingly. Clin. Anat. 25:1087–1092, 2012. © 2012 Wiley Periodicals, Inc.
Sonogashira–Hagihara Coupling towards Diaryl Alkynes Catalyzed by FeCl3⋅6 H2O/Cationic 2,2'‐Bipyridyl
Authors: Hung Tzu‐Ting , Huang Chun‐Min , Tsai Fu‐Yu 
Published: February 2012

AbstractEfficient and environmentally benign one‐pot Sonogashira–Hagihara coupling of aryl iodides with 4‐aryl‐2‐methylbut‐3‐yn‐2‐ols catalyzed by an FeCl3⋅6 H2O/cationic 2,2'‐bipyridyl system in water under air in the presence of zinc powder reductant was performed. Various aryl iodides and 4‐aryl‐2‐methylbut‐3‐yn‐2‐ols were used as reactants, which afforded moderate to high yields of cross‐coupled products. Although alkyl‐substituted 2‐methylbut‐3‐yn‐2‐ol could not be coupled with aryl iodides, the use of alkyl terminal alkynes under similar conditions provided the corresponding products in moderate yields. This reaction protocol was also used to synthesize both symmetric and asymmetric 1,4‐diarylbuta‐1,3‐diynes. This one‐pot iron‐catalyzed Sonogashira–Hagihara coupling reaction progressed without the use of an organic solvent, a copper cocatalyst, or an inert atmosphere, rendering it an environmentally friendly method with potential for practical applications.
CO2 Capture in SOFC by Vapor Condensation and CH4 Production in SOEC Storing Excess Electricity
Authors: Schlitzberger C. , Brinkmeier N. O. , Leithner R. 
Published: February 2012

AbstractSimple CO2 capture in combined solid oxide fuel cell (SOFC) gasification or reforming (of hydrocarbons – fossil or biomass) cycles by condensing the water vapor of the anode exhaust gas after CO shifting and H2 recycling by a membrane is simulated. High efficiency of about 60 % is demonstrated. The separated CO2 can be stored in a two‐chamber tank at the same pressure and temperature as methane on the two sides of a flexible membrane which divides the tank into chambers since 1 mol CH4 results in 1 mol CO2. In a solid oxide electrolyzer cell (SOEC), CO2 and steam can be recombined to CH4 using excess electricity, e.g., produced by wind or solar power, and O2 is left over. Thus, excess electricity can be stored chemically. Such a cycle allows hybrid vehicles with SOFC as range extender, running as zero‐emission vehicles also when using natural gas.
Dual Emission from Rhenium(I) Complexes Induced by an Interligand Aromatic Interaction
Authors: Morimoto Tatsuki , Ito Megumi , Koike Kazuhide , Kojima Tatsuhiro , Ozeki Tomoji , Ishitani Osamu 
Published: February 2012

AbstractA series of rhenium(I) diimine complexes cis,trans‐[Re(dmb)(CO)2(PR1R2R3)(PR4R5R6)]+ (dmb=4,4′‐dimethyl‐2,2′‐bipyridine, Rn=phenyl or alkyl), each of which bears two phosphine ligands with various numbers of phenyl groups, has been synthesized by using the photochemical ligand‐substitution reaction. Detailed studies of the structural features, not only in the crystal but also in solution, indicate that the number of phenyl groups is a crucial factor in controlling the rotational conformation of the phosphine ligands, which in turn determines the extent of the π–π interaction between the aromatic diimine ligand and the phenyl group(s). The π–π interaction strongly affected both electrochemical and photophysical properties: 1) the oxidation power of the Re complex became stronger, 2) the lifetime of the excited state became longer, and 3) the Stokes shift between the 1MLCT absorption band and emission from the corresponding 3MLCT excited state became smaller. In particular, the diphenyl and triphenyl phosphine had much greater influence on the properties than the monophenyl phosphine ligand. Dual emission was observed from the different rotational conformers of the complexes with an intermediate number of phenyl groups in the phosphine ligands.
ChemInform Abstract: Molecular Engineering Design to Resolve the Layering Habit and Polymorphism Problems in Deep UV NLO Crystals: New Structures in MM′Be2B2O6F (M: Na, M′: Ca; M: K, M′: Ca, Sr).
Authors: Huang Hongwei , Yao Jiyong , Lin Zheshuai , Wang Xiaoyang , He Ran , Yao Wenjiao , Zhai Naixia , Chen Chuangtian 
Published: February 2012

AbstractNaCaBe2B2O6F (I), KCaBe2B2O6F (II), and KSrBe2B2O6F (III) are prepared by solid state reaction using CaCO3, SrCO3, BeO, B2O3, NaF, KF, CaF2, and SrF2 as starting materials (710—740 °C, 48 h).
ChemInform Abstract: Metal Oxidation with N2O5: The Nitrosylium Nitrates (NO)Cu(NO3)3, (NO)2[Zn(NO3)4] and (NO)6 [Ni4(NO3)12] (NO3)2·(HNO3).
Authors: Gagelmann Steffen , Riess Katja , Wickleder Mathias S. 
Published: February 2012

AbstractN2O5 is prepared by reaction of fuming HNO3 with P4O10 and directly condensed on the metal powders.
ChemInform Abstract: α‐Diketones as Acyl Anion Equivalents: A Non‐Enzymatic Thiamine‐Promoted Route to Aldehyde—Ketone Coupling in PEG400 as Recyclable Medium.
Authors: Bortolini Olga , Fantin Giancarlo , Fogagnolo Marco , Giovannini Pier Paolo , Venturi Valentina , Pacifico Salvatore , Massi Alessandro 
Published: February 2012

AbstractThe homocoupling reaction of α‐diketones, e.g. (I), is smoothly mediated by thiazolium salt HETP or, more conveniently, by catalytic amounts of commercially available thiazolium salt HEBT.
ChemInform Abstract: A Novel Efficient and Chemoselective Method for the Reduction of Nitriles Using the System Silane/Oxo‐Rhenium Complexes.
Authors: Cabrita Ivania , Fernandes Ana C. 
Published: February 2012

AbstractTitle reaction tolerates a wide range of functional groups, including aromatic halides, sulfone, sulfonamide and (thio)ether groups.
ChemInform Abstract: An Efficient Pd‐Catalyzed Coupling of Hydrazine Derivatives with Aryl Halides.
Authors: Ma Fang‐Fang , Peng Zhi‐Yong , Li Wan‐Fang , Xie Xiao‐Min , Zhang Zhaoguo 
Published: February 2012

AbstractA convenient protocol is developed to give a variety of ortho‐, meta‐, and para‐substituted N‐arylhydrazines.
ChemInform Abstract: The Hydroamination of Alkenes with Sulfonamides Catalyzed by the Recyclable Silica Gel Supported Triflic Acid.
Authors: Liu Pei Nian , Xia Fei , Zhao Zheng Le , Wang Qing Wei , Ren Yu Jie 
Published: February 2012

AbstractTwo versions including triflic acid adsorbed on silica gel are used for the title reaction and generally similar yields are produced.
ChemInform Abstract: Stereocontrolled Formation of Styrenes by Pd(0)‐Catalyzed Cross‐Coupling of Photoactivated (E)‐Alkenylgermanes with Aryl Bromides.
Authors: Tseng Chih‐Chung , Li Mungyuen , Mo Bingli , Warren Sarah A. , Spivey Alan C. 
Published: February 2012

AbstractThe use of PCy3.HBF4 instead of P(o‐tolyl)3 gives higher (E)‐selectivity, cf.
ChemInform Abstract: Carbon Dioxide Mediated Synthesis of 3(2H)‐Furanones from Diyne Alcohols.
Authors: Yuan Gaoqing , He Zaijun , Zheng Junhua , Chen Zhengwang , Huang Huawen , Shi Dabin , Qi Chaorong , Jiang Huanfeng 
Published: February 2012

AbstractThe metal‐free procedure renders possible the preparation of various furanone structures bearing a benzylic side chain.
ChemInform Abstract: Water‐Compatible One‐Pot Organocatalytic Asymmetric Synthesis of Cyclic Nitrones. Application in Intramolecular 1,3‐Dipolar Cycloaddition.
Authors: Sadaba David , Delso Ignacio , Tefero Tomas , Merino Pedro 
Published: February 2012

AbstractA series of enantiopure five‐membered cyclic nitrones (III) is synthesized through asymmetric Michael addition of enolizable aldehydes to nitroalkenes followed by one‐pot Zn‐promoted reductive cyclization.
ChemInform Abstract: Syntheses of Indolo[3,2,1‐d,e]phenanthridines and Isochromeno[3,4‐a]carbazoles: Palladium‐Catalyzed Intramolecular Arylation via C—H Functionalization.
Authors: Yamuna Ezhumalai , Zeller Matthias , Prasad Karnam Jayarampillai Rajendra 
Published: February 2012

AbstractThe title compounds (IV) and (VII) are easily prepared by alkylation of appropriate carbazole‐type precursors with o‐bromobenzyl bromide and following Pd‐catalyzed cyclization.
ChemInform Abstract: Discovery of Novel Hepatoselective HMG‐CoA Reductase Inhibitors for Treating Hypercholesterolemia: A Bench‐to‐Bedside Case Study on Tissue Selective Drug Distribution.
Authors: Pfefferkorn Jeffrey A. , et al. et al. 
Published: February 2012

AbstractReplacement of the pyrrole core of atorvastatin with five‐membered heterocycles and further improvement of the hepatoselectivity of the resulting pyrazole‐based HMG‐CoA inhibitor candidate lead to imidazole‐based HMG‐CoA reductase inhibitors such as (I).
ChemInform Abstract: Synthesis of 2‐(1H‐1,2,3‐Triazol‐1‐yl)‐1,4‐naphthoquinones from 2‐Azido‐1,4‐naphthoquinone and Terminal Alkynes.
Authors: do Nascimento Wilson Silva , Camara Celso Amorim , Nascimento de Oliveira Ronaldo 
Published: February 2012

AbstractThe optimized conditions allow the preparation of the triazoles in a regioselective manner including the sugar derivative (V).
ChemInform Abstract: Catecholthioether Derivatives: Preliminary Study of in vitro Antimicrobial and Antioxidant Activities.
Authors: Adibi Hadi , Rashidi Atefeh , Khodaei Mohammad Mehdi , Alizadeh Abdolhamid , Majnooni Mohammad Bagher , Pakravan Narges , Abiri Ramin , Nematollahi Davood 
Published: February 2012

Abstract8 Aromatic catecholthioethers of type (III) or (V) (no yields given) are prepared by anodic oxidation.
ChemInform Abstract: Direct Transformation of Baylis—Hillman Acetates into N‐Substituted Quinolones Through an SN2′→SNAr→ (Δ3.4—Δ2,3 Shift) → Oxidation Sequence.
Authors: Napoleon John Victor , Manheri Muraleedharan Kannoth 
Published: February 2012

AbstractA reaction pathway is developed to access 4‐ and 2‐quinolones in low to moderate yields.
ChemInform Abstract: A Novel Approach for Synthesis of 3‐Amino‐5‐aryl‐2,5‐dihydropyridazines Using Onium Salt as Soluble Support.
Authors: Gao Meng , Lu Cui Fen , Yang Gui Chun , Chen Zu Xing 
Published: February 2012

AbstractThe conversion of the onium salt (III) into the title compounds involves Knoevenagel condensation with aromatic aldehydes, Michael addition with phenylhydrazone (III) and cleavage from the support using triethylamine in ethanol.
ChemInform Abstract: Synthesis and in vitro Antiprotozoal Activities of 5‐Phenyliminobenzo[a]phenoxazine Derivatives.
Authors: Shi Xue‐Liang , Ge Jian‐Feng , Liu Bao‐Qiang , Kaiser Marcel , Wittlin Sergio , Brun Reto , Ihara Masataka 
Published: February 2012

AbstractNotably, benzo[a]phenoxazines (IIIb) and (IIIc) with methoxyphenylimino groups in 5‐position show good in vitro antiprotozoal activity against P.
ChemInform Abstract: A Convenient Method to Access Long‐Chain and Functionalized Mixed Methylphosphonate Esters and Their Application in the Synthesis of Ionic Liquids.
Authors: Sachnov Swetlana J. , Schulz Peter S. , Wasserscheid Peter 
Published: February 2012

AbstractThe solvent‐free reaction of ionic liquid (I) with alkyl halides (II) leads to the mixed methylphosphonate esters (III), which are used for the synthesis of novel methylphosphonate ionic liquids such as (V) and (VII).
ChemInform Abstract: Synthesis of Diaryl Selenides Using Electrophilic Selenium Species and Nucleophilic Boron Reagents in Ionic Liquids.
Authors: Freitas Camilo S. , Barcellos Angelita M. , Ricordi Vanessa G. , Pena Jesus M. , Perin Gelson , Jacob Raquel G. , Lenardao Eder J. , Alves Diego 
Published: February 2012

AbstractImidazolium ionic liquids efficiently promote the selective synthesis of unsymmetrical diaryl selenides under mild conditions.
ChemInform Abstract: Antioxidative Sesquiterpenes from Artemisia iwayomogi.
Authors: Ding Yan , Kim Jeong Ah , Yang Seo Young , Kim Won‐Ki , Lee Sang Hyun , Jang Hae Dong , Kim Young Ho 
Published: February 2012

AbstractAll the sesquiterpenes isolated (8 examples) except for compound (V), exhibit significant radical‐scavening capacity and reducing capacity.
ChemInform Abstract: Secoiridoid Glucosides and Related Compounds from Syringa reticulata and Their Antioxidant Activities
Authors: Bi Xueyan , Li Wei , Sasaki Tatsunori , Li Qin , Mitsuhata Naoko , Asada Yoshihisa , Zhang Qingbo , Koike Kazuo 
Published: February 2012

Abstractisolation, structures and superoxide anion scavenging activity of seventeen compounds including the novel oleoside‐type secoiridoid glucoside, reticuloside (I)
ChemInform Abstract: Antimycins A19 and A20, Two New Antimycins Produced by Marine Actinomycete Streptomyces antibioticus H74‐18.
Authors: Xu Lin‐Ya , Quan Xue‐Sheng , Wang Chen , Sheng Hui‐Fang , Zhou Guang‐Xiong , Lin Bi‐Run , Jiang Ren‐Wang , Yao Xin‐Sheng 
Published: February 2012

AbstractThe two new antimycin antibiotics antimycin A19 (Ia) and antimycin A20 (Ib) are isolated from a cultured broth of the marine actinomycete Streptomyces antibioticus H74‐18 along with 5 known antimycins.
ChemInform Abstract: A New Cytotoxic Indole‐3‐ethenamide from the Halotolerant Fungus Aspergillus sclerotiorum PT06‐1.
Authors: Wang Hui , Zheng Jin‐Kai , Qu Hai‐Jun , Liu Pei‐Pei , Wang Yi , Zhu Wei‐Ming 
Published: February 2012

AbstractThe new indole derivative (I) is isolated along with two known compounds from the ethyl acetate extract of Aspergillus sclerotiorum PT06‐1 in a hypersaline nutrient‐rich medium.
In situ upgrading of bitumen and heavy oils via nanocatalysis
Authors: Almao P. Pereira 
Published: February 2012

AbstractThermal in situ bitumen production has introduced a different engineering approach compared to conventional oil exploitation. Steam injection for example, allows the development of a relatively confined liquid and gas chamber surrounding and along the length of the production wells. This heated place can be converted into a reactor for upgrading processes founding expectations of extensive reservoir upgrading of unconventional oils reducing the total energy currently required to both exploit the reservoir and surface upgrade the produced bitumen. These could also selectively transform contaminants into harmless products remaining in the reservoir. This article highlights the nanocatalytic in situ upgrading paths that may result in economical and environmentally efficient oil sands exploitation. © 2012 Canadian Society for Chemical Engineering
Discovery of Novel 2‐N‐Aryl‐Substituted Benzenesulfonamidoacetamides: Orally Bioavailable Tubulin Polymerization Inhibitors with Marked Antitumor Activities
Authors: Liu Zulong , Zhou Zuyu , Tian Wei , Fan Xing , Xue Ding , Yu Long , Yu Qiang , Long Ya‐Qiu 
Published: February 2012

AbstractThe discovery and optimization of a series of 2‐N‐aryl‐substituted benzenesulfonamidoacetamides as novel tubulin polymerization inhibitors are described. Pharmacophore exploration of hit compound AH‐487 identified the optimal structure of N‐heteroaryl‐2‐(4‐methoxy‐N‐(3‐(trifluoromethyl)phenyl)phenylsulfonamido)acetamide as a potent antimitotic agent. Subsequent lead compounds 4 b and 4 c, with N‐4‐aminophenyl and N‐1H‐indol‐5‐yl substitutions at the acetamide position, respectively, were shown to induce cell‐cycle arrest at the G2/M phase and lead to an accumulation of HeLa cells in the sub‐G1 phase. More significantly, these lead compounds (3 c, 4 b, and 4 c) exhibit impressive cytotoxicity against a panel of cancer cells including P‐glycoprotein‐overexpressing MDR‐positive cells, with potency greater than or equal to clinically studied benzenesulfonamide E7010. Mechanistic studies demonstrated that derivatives of AH‐487 disrupt mitotic spindles by inhibiting microtubule polymerization and induce apoptosis via induction of Bcl‐2 phosphorylation in tumor cells. The optimized leads 4 b and 4 c strongly inhibited the growth of human hepatocellular carcinoma cells in a mouse xenograft model.