bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of supply chain partnership, cross-functional integration, responsiveness and resilience on competitive advantages: empirical evidence from Palestine
Authors: Badwan Nemer 
Published: May 2024

PurposeThe external business environment of the organization is always changing at a rapid pace. For a firm to adapt to changing client requirements, it must implement the right business procedures and strategies. To improve competitive advantage, this study investigates the roles that supply chain partnerships, cross-functional integration, responsiveness and resilience play in achieving competitive advantages in Palestine.Design/methodology/approachIndustrial institutions in Palestine constitute the study population. Data are collected by distributing surveys via Google Forms linked to manufacturers in industries such as the Leather and shoe Industry, metal industries, chemical industries, construction industries, textile industries, stone and marble industries, pharmaceutical industry, veterinary industry, food industry, plastic industry, paper industry, major advantages and disadvantages. The SEM-PLS approach is used to analyze the data.FindingsThe findings demonstrate that supply chain responsiveness, resilience and cooperation are all improved by cross-functional integration in inventory data integration and immediate operation. Supply chain partnerships improve the supply chain’s responsiveness, resilience and competitive advantage by involving partners in work teams and exchanging best practices. The enhancement of supply chain resilience and competitive advantage is influenced by the company’s capacity to act promptly in response to variations in demands.Research limitations/implicationsThis paper faces some limitations and it can be drawn as follows: To enhance supply chain risk management, the study continues to concentrate on manufacturing organizations that have internal integration. It also emphasizes the necessity of supply chain integration, which establishes direct connections with outside partners.Practical implicationsThe findings of this study suggest some policy implications, as follows: To provide the manufacturing sector with a competitive edge, operations supervisors must be able to track and assess processes to ensure they are meeting demand. Firms that possess the ability to adjust to novel procedures or advancements in technology gain a competitive edge by guaranteeing consistent and high-quality delivery of products.Originality/valueBy implementing IT integration, this study theoretically and practically advances the understanding of the resource-based view of competitive advantages. This study focuses on providing insights into the nature of the relationship between supply chain partnership, cross-functional integration, responsiveness and flexibility and competitive advantages in the manufacturing sector in the Palestinian market.
Biogeography and impact of nitrous oxide reducers in rivers across a broad environmental gradient on emission rates
Authors: Zhang Sibo , Xia Xinghui , Yu Leilei , Liu Shaoda , Li Xiaokang , Wang Junfeng , Zheng Yue , Han Lanfang , Tan Qian , Yang Zhifeng 
Published: May 2024

AbstractMicrobial communities that reduce nitrous oxide (N2O) are divided into two clades, nosZI and nosZII. These clades significantly differ in their ecological niches and their implications for N2O emissions in terrestrial environments. However, our understanding of N2O reducers in aquatic systems is currently limited. This study investigated the relative abundance and diversity of nosZI‐ and nosZII‐type N2O reducers in rivers and their impact on N2O emissions. Our findings revealed that stream sediments possess a high capacity for N2O reduction, surpassing N2O production under high N2O/NO3‐ ratio conditions. This study, along with others in freshwater systems, demonstrated that nosZI marginally dominates more often in rivers. While microbes containing either nosZI and nosZII were crucial in reducing N2O emissions, the net contribution of nosZII‐containing microbes was more significant. This can be attributed to the nir gene co‐occurring more frequently with the nosZI gene than with the nosZII gene. The diversity within each clade also played a role, with nosZII species being more likely to function as N2O sinks in streams with higher N2O concentrations. Overall, our findings provide a foundation for a better understanding of the biogeography of stream N2O reducers and their effects on N2O emissions.
Habitat conditions and not moss composition mediate microbial community structure in Swiss peatlands
Authors: Korn Rachel , Berg Christian , Bersier Louis‐Félix , Gray Sarah M. , Thallinger Gerhard G. 
Published: May 2024

AbstractPeatlands, one of the oldest ecosystems, globally store significant amounts of carbon and freshwater. However, they are under severe threat from human activities, leading to changes in water, nutrient and temperature regimes in these delicate systems. Such shifts can trigger a substantial carbon flux into the atmosphere and diminish the water‐holding capacity of peatlands. Microbes associated with moss in peatlands play a crucial role in providing these ecosystem services, which are at risk due to global change. Therefore, understanding the factors influencing microbial composition and function is vital. Our study focused on five peatlands along an altitudinal gradient in Switzerland, where we sampled moss on hummocks containing Sarracenia purpurea. Structural equation modelling revealed that habitat condition was the primary predictor of community structure and directly influenced other environmental variables. Interestingly, the microbial composition was not linked to the local moss species identity. Instead, microbial communities varied significantly between sites due to differences in acidity levels and nitrogen availability. This finding was also mirrored in a co‐occurrence network analysis, which displayed a distinct distribution of indicator species for acidity and nitrogen availability. Therefore, peatland conservation should take into account the critical habitat characteristics of moss‐associated microbial communities.
Alien range size, habitat breadth, origin location, and domestication of alien species matter to their impact risks
Authors: WANG Siqi , LI Wenhao , ZHANG Jiaqi , LUO Zexu , LI Yiming 
Published: May 2024

AbstractInvasive alien species are a major driver of biodiversity loss. Currently, the process of biological invasions is experiencing a constant acceleration, foreshadowing a future increase in the threat posed by invasive alien species to global biodiversity. Therefore, it is necessary to assess the impact risks of invasive alien species and related factors. Here, we constructed a dataset of negative environmental impact events to evaluate the impact risks of alien species. We collected information on 1071 established alien terrestrial vertebrates and then gathered negative environmental impacts for 108 of those species. Generalized linear mixed‐effects model and phylogenetic generalized least‐squares regression model were used to examine the characteristic (including life‐history traits, characteristics related to distribution, and introduction event characteristics) correlates of species’ impact risks at the global scale for 108 established alien terrestrial vertebrates (mammals, birds, reptiles and amphibians). Our results showed that a total of 3158 negative environmental impacts were reported for 108 harmful species across 71 countries worldwide. Factors associated with impact risks varied slightly among taxa, but alien range size, habitat breadth, origin location, and domestication were significantly correlated with impact risks. Our study aims to identify the characteristics of alien species with high‐impact risks to facilitate urgent assessment of alien species and to protect the local ecological environment and biodiversity.
LEMD2‐associated progeroid syndrome: Expanding the phenotype of the nuclear envelopathy caused by a defect in LEMD2 gene
Authors: Matter Alyssia , Kaufman Christina , Zürcher Nadia , Lenggenhager Daniela , Grehten Patrice , Bartholdi Deborah , Horka Laura , Häberle Johannes , Makris Georgios 
Published: May 2024

AbstractNuclear envelopathies are rare genetic diseases that compromise the integrity of the nuclear envelope. Patients with a defect in LEM domain nuclear envelope protein 2 (LEMD2) leading to LEMD2‐associated progeroid syndrome are exceedingly scarce in number, yet they exhibit shared clinical features including skeletal abnormalities and a prematurely‐aged appearance. Our study broadens the understanding of LEMD2‐associated progeroid syndrome by detailing its phenotypic and molecular characteristics in the first female and fourth reported case, highlighting a distinct impact on metabolic functions. The patient's history revealed growth delay, facial and skeletal abnormalities, and recurrent abdominal pain crises caused by hepatomegaly. Comparisons with the previously documented cases emphasized similarities in skeletal and facial features while showcasing unique variations, notably in cardiac and hepatic manifestations. In vitro experiments conducted on patient‐derived peripheral blood and urinary epithelial cells and LEMD2‐downregulated HepG2 cells confirmed abnormalities in the structure of the nuclear envelope in all three tissue‐types. Overall, our work offers a comprehensive profile of a patient with LEMD2‐related syndrome, emphasizing the hepatic involvement in the disease and broadening our understanding of clinical and molecular implications. This study not only contributes specific insights into LEMD2‐related conditions but also underscores potential therapeutic paths for disorders affecting nuclear envelope dynamics.
Obsidian in the Caribbean islands? Mysterious Ceramic Age glass artefacts in the Lesser Antilles
Authors: Leck Arthur , Bellot‐Gurlet Ludovic , Carazzo Guillaume , Gratuze Bernard , Langlade Jessica , Le Bourdonnec François‐Xavier , Leandri Céline , Shearn Isaac , Stouvenot Christian , Queffelec Alain 
Published: May 2024

AbstractThe Caribbean islands witnessed a population expansion of ceramic‐using horticulturalists during the Early Ceramic Age (ca. 500 BC to 750 AD) from the Orinoco Valley to Puerto Rico. We examined 18 lithic artefacts from Guadeloupe and Dominica initially thought to be obsidian, a material believed to be absent from those islands. We investigated the volcanic or meteoritic origin of this unique and yet unknown material through observation (binocular, SEM, microtomography) and geochemical analyses (PIXE, SEM‐EDS, ED‐XRF, EPMA, LA‐ICP‐MS). Elemental analyses rule out the hypothesis of an origin from a meteoritic impact (i.e. identification as tektites). Most of the artefacts have an andesitic composition (<63% SiO2), which appears to be unique among ‘massive’ glasses. The only artefact with a rhyolitic composition has been traced back to the Guadeloupe's Volcan du Tuf, where glassy fragments have been collected and analysed. The geological source of the other vitreous artefacts that exhibit an andesitic composition could be from a sublocal subduction‐arc volcanism (maybe from Martinique), although no volcanic vitreous material of this kind has ever been reported worldwide. These results once again highlight the regional mobility of Early Ceramic populations and the production of standard lithic products using a highly original, albeit low‐quality, local lithic resource, and provide valuable references for future identification of similar materials.
A Bayesian alternative for aoristic analyses in archaeology
Authors: Crema Enrico R. 
Published: May 2024

AbstractAoristic analysis is often used to handle chronological uncertainties of datasets where scientific dates (e.g., 14C and OSL) are unavailable, and observations are described by association to archaeological periods or phases. Although several advances have been made over the last 2 decades, the basic principle of this approach remains fundamentally the same. Temporal windows of analyses are first divided into regularly sized time blocks, and probability weight is assigned to each of these for every observation. Weights are then aggregated by time block, and the resulting vector of summed probabilities is interpreted as a curve representing changes in the intensity over time of a particular phenomenon. This paper reviews the basic principles and assumptions of aoristic analyses in archaeology, highlighting several issues with its application and interpretation, advocating for a Bayesian alternative implemented via baorista, a new package written in R statistical computing language. The robustness of the proposed solution is evaluated through a series of experiments based on simulated datasets, which showcase key advantages over aoristic analysis. Two specific solutions are considered: a parametric approach where data are fitted to specific growth models and a nonparametric approach that allows for the visualisation of the changing frequencies of events, accounting for sampling error and the peculiarities of archaeological periodisation.
The Mediating Role of Moral Disengagement in the Association Between Maltreatment and Bullying Perpetration: Testing the Differences of Gender and Household Registration
Authors: Fan Xiaoyan 
Published: May 2024

ABSTRACTAlthough previous studies have indicated that adverse childhood experiences profoundly impact children's psychological and behavioural development, comprehensive investigations into the direct and indirect mechanisms through which maltreatment affects bullying perpetration among Chinese children are lacking. This study aims to explore the effect of maltreatment on children's bullying perpetration and the potential mediating role of moral disengagement. Moreover, the gender and household registration differences in the associations are also investigated. Employing a multistage cluster sampling method, 1318 questionnaires were collected (612 males, 706 females, mean age = 15). Structural equation modelling was used to analyse the hypothesized theoretical model. The findings reveal that the experiences of maltreatment in early childhood directly influence children's bullying perpetration, with moral disengagement potentially mediating this association. Furthermore, substantial gender disparities exist in the effect of maltreatment on bullying perpetration, and notable variations based on household registration are observed in the association of maltreatment on children's moral disengagement. These findings enhance our understanding of how childhood maltreatment affects children's bullying perpetration and offer valuable insights for the development of social policy and intervention programmes targeting child maltreatment and school bullying.
The Sultan Mehmed the Conqueror Museum: The museumization of a cultural asset for an Ottoman conqueror
Authors: Diker Hasan Fırat 
Published: May 2024

AbstractConversion to a museum is a common destiny of many cultural assets that cannot continue to serve their original functions. They are usually re‐functioned to provide public benefits in return for the expenditures made for their preservation. However, their architectural features may not always meet the expected results when functioning as a museum. The spatial limitations arising in such conversions are the main design gaps in the museumization projects. This article aims to address these gaps using a sample project of a museum on Sultan Mehmed the Conqueror converted from a medieval education structure.
Inclisiran in individuals with diabetes or obesity: Post hoc pooled analyses of the ORION‐9, ORION‐10 and ORION‐11 Phase 3 randomized trials
Authors: Leiter Lawrence A. , Raal Frederick J. , Schwartz Gregory G. , Koenig Wolfgang , Ray Kausik K. , Landmesser Ulf , Han Jackie , Conde Lorena Garcia , Wright R. Scott 
Published: May 2024

AbstractAimsTo conduct a pooled analysis of Phase 3 trials investigating the efficacy and safety of inclisiran across glycaemic and body mass index (BMI) strata.Materials and MethodsParticipants were randomized 1:1 to receive 300 mg inclisiran sodium or placebo twice yearly, after initial and 3‐month doses up to 18 months, with background oral lipid‐lowering therapy. Analyses were stratified by glycaemic status (normoglycaemia, prediabetes, and diabetes) or BMI (<25, ≥25 to <30, ≥30 to <35, and ≥35 kg/m2). Co‐primary endpoints were percentage and time‐adjusted percentage change in low‐density lipoprotein (LDL) cholesterol from baseline. Safety was also assessed.ResultsBaseline characteristics were balanced between treatment arms and across strata. Percent LDL cholesterol change (placebo‐corrected) with inclisiran from baseline to Day 510 ranged from −47.6% to −51.9% and from −48.8% to −54.4% across glycaemic/BMI strata, respectively. Similarly, time‐adjusted percentage changes after Day 90 and up to Day 540 ranged from −46.8% to −52.0% and from −48.6% to −53.3% across glycaemic/BMI strata, respectively. Inclisiran led to significant reductions in proprotein convertase subtilisin/kexin type 9 and other atherogenic lipids and lipoproteins versus placebo across the glycaemic/BMI strata. The proportions of individuals achieving LDL cholesterol thresholds of <1.8 mmol/L and <1.4 mmol/L with inclisiran increased with increasing glycaemic and BMI strata. Across the glycaemic/BMI strata, a higher proportion of individuals had mild/moderate treatment‐emergent adverse events (TEAEs) at the injection site with inclisiran (2.8%–7.7%) versus placebo (0.2%–2.1%).ConclusionInclisiran provided substantial and sustained LDL cholesterol lowering across glycaemic/BMI strata, with a modest excess of transient mild‐to‐moderate TEAEs at the injection site.
Does community resilience affect household asset portfolio choices?
Authors: Zheng Yi 
Published: May 2024

AbstractThis paper identifies a positive (negative) relationship between community resilience and household stock market participation (deposit flows). These relationships are less pronounced for higher‐income and married households, indicating an income channel and a marriage channel, respectively. Furthermore, compared to white and Asian households, black households are more sensitive to the effects of community resilience on household investments and deposit flows. Overall, our findings suggest that improvements in people's preparedness for, resilience against, and recovery from potential hazardous events and natural disasters shift households' asset portfolio choices from safe savings to risky stock investments.
Efficacy and safety of dolutegravir/lamivudine in virologically suppressed female participants: week 48 data from the pooled TANGO and SALSA studies
Authors: Katlama C. , Bisshop F. , Bogner J. , Pérez Elías M. J. , Di Giambenedetto S. , Clarke E. , Hodder S. , Nwokolo N. , Ait‐Khaled M. , Oyee J. , Grove R. , Wynne B. , Okoli C. , Jones B. , Kisare M. 
Published: May 2024

AbstractObjectivesWomen represent >50% of people with HIV globally but have historically been underrepresented in clinical trials. We evaluated the efficacy and safety of switching to dolutegravir/lamivudine (DTG/3TC) vs continuing their current antiretroviral regimen (CAR) by sex assigned at birth (female and male) in virologically suppressed adults with HIV‐1 without prior virological failure in a pooled analysis of two randomized controlled trials.MethodsThis analysis included 48‐week data from the phase 3 TANGO and SALSA studies. Primary and key secondary endpoints included proportions of participants with HIV‐1 RNA ≥50 and <50 copies/mL at week 48, respectively. Safety was also assessed.ResultsOf 1234 participants, 250 (DTG/3TC, n = 133; CAR, n = 117) were female at birth. Week 48 proportions of participants with Snapshot HIV‐1 RNA ≥50 copies/mL were similar regardless of sex at birth (DTG/3TC vs CAR: female, <1% [1/133] vs 2% [2/117]; male, <1% [1/482] vs <1% [3/502]). Proportions with HIV‐1 RNA <50 copies/mL were high across sexes and treatment groups (DTG/3TC vs CAR: female, 91% [121/133] vs 89% [104/117]; male, 94% [455/482] vs 94% [471/502]). Immunological response with DTG/3TC was slightly higher in female participants. Incidences of adverse events leading to withdrawal and serious adverse events were low and comparable between treatment groups and across sexes. Weight gain was higher with DTG/3TC than with CAR among female participants aged ≥50 years (treatment difference 2.08 kg [95% confidence interval 0.40–3.75]).ConclusionsResults confirm the robustness of DTG/3TC as a switch option in virologically suppressed females with HIV‐1, with outcomes similar to those in males.
Anatomical outcomes and complications of sacrocolpopexy using Surelift Uplift mesh: A multicentric observational study
Authors: Calleja Hermosa Paola , Sánchez Guerrero Clara , Viegas Vanessa , Rebassa LLul Miguel , Jiménez Cidre Miguel , Morán Pascual Eduardo , Errando Smet Carlos , Arlandis Guzmán Salvador , Martínez Cuenca Esther , Gómez de Vicente José Miguel , Ruiz Hernández Mercedes , Casado Varela Javier , Mora Gurrea Jorge , Pérez Polo María , López‐Fando Lavalle Luis 
Published: May 2024

ObjectiveThe study evaluated the anatomical and functional outcomes, as well as the safety data of laparoscopic sacrocolpopexy (LSC) for pelvic organ prolapse (POP) using a lightweight macroporous mesh.MethodsA multicentric observational study was developed including five expert centers between March 2011 and December 2019. Inclusion criteria were female patients with symptomatic ≥stage II POP (POP‐Q classification), who underwent a LSC. A lightweight and macroporous mesh device (Surelift Uplift) was used. Baseline anatomical positions were evaluated using POP‐Q stage. The anatomical outcomes and procedural complications were assessed during the postoperative period. Primary outcomes were anatomical success, defined as POP‐Q stage ≤I, and subjective success, defined as no bothersome bulge symptoms, and no repeat surgery or pessary use for recurrent prolapse.ResultsA total of 325 LSCs were analyzed with a median patient age of 66 (interquartile range [IQR] 61–73). After a median follow‐up of 68 months (IQR 46.5–89), anatomical success was found in 88.9%, whereas subjective success was seen in 98.5% of the patients. Recurrent prolapse presented as cystocele (1.5%). Reported complications were bladder (4.6%) or rectum lesions (0.6%), de novo urinary incontinence (12.9%), and mesh extrusion (1.2%).ConclusionsLSC provides significant clinical improvement and excellent anatomical results, with a low risk of serious complications for women with ≥2 grade POP in a real clinical practice setting.
Longest recorded migration of a silky shark (Carcharhinus falciformis) reveals extensive use of international waters of the Tropical Eastern Pacific
Authors: Salinas‐de‐León Pelayo , Vaudo Jeremy , Logan Ryan , Suarez‐Moncada Jenifer , Shivji Mahmood 
Published: May 2024

AbstractDespite being a heavily fished species, little is known about the movements of silky sharks (Carcharhinus falciformis). In this study, we report the longest (in duration and distance traveled) and most spatially extensive recorded migration for a silky shark. This shark, tagged with a fin‐mount satellite transmitter at the Galapagos Islands, traveled >27,666 km over 546 days, making two westerly migrations into international waters as far as 4755 km from the tagging location. These extensive movements in an area with high international fishing effort highlights the importance of understanding silky shark migrations to inform management practices.