bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymorphisms in the CASPASE Genes and Survival in Patients With Early-Stage Non–Small-Cell Lung Cancer
Authors: Yoo Seung Soo , Choi Jin Eun , Lee Won-Kee , Choi Yi-Young , Kam Sin , Kim Min Jung , Jeon Hyo-Sung , Lee Eung-Bae , Kim Dong Sun , Lee Myung-Hoon , Kim In-San , Jheon Sanghoon , Park Jae Yong 
Published: October 2009

Purpose This study was conducted to determine the impact of potentially functional polymorphisms in the CASPASE (CASP) genes on the survival of early-stage non–small-cell lung cancer (NSCLC) patients. Patients and Methods Four hundred eleven consecutive patients with surgically resected NSCLC were enrolled. Nine potentially functional polymorphisms in the CASP3, CASP7, CASP8, CASP9, and CASP10 genes were investigated. The genotype and haplotype associations with overall survival (OS) and disease-free survival (DFS) were analyzed. Results Patients with the rs2227310 GG genotype had a significantly decreased OS and DFS compared with patients with the CC + CG genotype (adjusted hazard ratio [aHR] for OS, 1.67; 95% CI, 1.19 to 2.35; P = .003; aHR for DFS, 1.62; 95% CI, 1.19 to 2.22; P = .002). The rs4645981C>T genotype also had a significant effect on OS and DFS (under a recessive model; aHR for OS, 2.00; 95% CI, 1.04 to 3.85; P = .04; aHR for DFS, 2.76; 95% CI, 1.58 to 4.80; P = .0003). When the rs2227310 and rs4645981 genotypes were combined, patients with one or two bad genotypes had worse OS and DFS compared with those who had zero bad genotypes (aHR for OS, 1.75; 95% CI, 1.25 to 2.45; P = .001; aHR for DFS, 1.66; 95% CI, 1.23 to 2.26; P = .001). Conclusion The CASP7 rs2227310 and CASP9 rs4645981 polymorphisms may affect survival in early-stage NSCLC. The analysis of these polymorphisms can help identify patients at high risk for a poor disease outcome.
Reversible Conversion of Tetranuclear, Trinuclear, and Mononuclear Palladium(II) Complexes with d-Penicillaminate
Authors: Yoshinari Nobuto , Hirai Yusuke , Kawamoto Tatsuya , Igashira-Kamiyama Asako , Tsuge Kiyoshi , Konno Takumi 
Published: October 2009

Abstract
The 1:1 reaction of [PdCl4]2− with d-penicillamine (d-H2pen) gave a S-bridged tetranuclear complex, [Pd4Cl4(d-Hpen)4] ([1]). Complex [1] was converted to a S-bridged trinuclear complex, [Pd3(d-pen)3] ([2]), which was further converted to a mononuclear complex, K2[Pd(d-pen)2] (K2[3]). The reverse conversion of [2] to [1] was also achieved.
Generations and Reactions of N-(t-Butylsulfonyl)aziridinyllithiums Using Microreactors
Authors: Nagaki Aiichiro , Takizawa Eiji , Yoshida Jun-ichi 
Published: October 2009

Abstract
N-tert-Butylsulfonyl(Bus)-α-phenylaziridinyllithium was effectively generated by the reaction of N-Bus-2-phenylaziridine with n-BuLi in a microflow system at −28 °C, although much lower temperatures such as −78 °C are needed for batch reactors. Subsequent reactions with various electrophiles gave the corresponding α-substituted N-Bus-2-phenylaziridines. Deprotonation of N-Bus-aziridine with s-BuLi was also achieved by using a microflow system at −78 °C, and the reaction of the resulting N-Bus-aziridinyllithium with electrophiles gave the substituted N-Bus-aziridines.
Bisphenol A Weakens Calcium Binding Affinity of Sites III and IV in C-Terminal Domain of Bovine Brain Calmodulin
Authors: Murayama Koichi , Sonoyama Masashi , Terada Tomoyoshi , Yokoyama Yasunori , Nara Masayuki , Tomida Mihoko , Matsuda Sadayuki 
Published: October 2009

Abstract
Ca2+-binding affinity of sites III and IV in C-terminal domain of calmodulin in the presence and absence of BPA using intrinsic Tyr fluorescence is reported. The titration curves were lower shifted for Ca2+ affinity in the presence of BPA, and Gibbs energy of calcium binding to both sites decreased. These results suggest that BPA weakens the Ca2+ affinity of domains III and IV of calmodulin.
Fabrication of a Thermoresponsive Surface by Photocrosslinking Amphiphilic Poly(amino acid)s
Authors: Takeuchi Yasushi , Tsujimoto Takashi , Uyama Hiroshi 
Published: October 2009

Abstract
A novel and convenient system to immobilize thermoresponsive poly(aspartic acid) derivatives on polystyrene surfaces was developed. Photoimmobilization of the thermoresponsive polymer was achieved by the partial introduction of cinnamoyl groups into the thermoresponsive poly(aspartic acid), following UV irradiation of the spin-coated thin layer. The thermoresponsive change of the surface properties was evaluated by the surface contact angle.
Evaluation of Compliance with Osteoporosis Treatment Guidelines After Initiation of a Pharmacist-Run Osteoporosis Service at a Family Medicine Clinic
Authors: Hall Larissa N , Shrader Sarah P , Ragucci Kelly R 
Published: October 2009

Background: Osteoporosis affects more than 10 million Americans, and fracture complications are devastating to patients and society. Despite the availability of guidelines and performance measures, osteoporosis is not optimally managed. Pharmacists have been pivotal in management of other disease states, and a multidisciplinary approach to osteoporosis management may improve patient outcomes. Objective: To establish a pharmacist-run osteoporosis service at a family medicine clinic and to evaluate short-term compliance with osteoporosis treatment guidelines before and after initiation of the service. Methods: A pharmacist-run osteoporosis service was established in October 2008. Adults with the diagnosis of osteoporosis before initiation of the service were included in evaluation of short-term compliance with treatment guidelines, including appropriate dual-energy X-ray absorptiometry (DEXA) scan frequency, pharmacotherapy, calcium and vitamin D supplementation, and nonpharmacologic education. Of 42 referred patients, 22 were eligible for inclusion. A retrospective chart review was conducted, and patients served as their own controls, with data from before and after establishment of the service evaluated. Results: Of the 22 patients evaluated, 8 (36%) received DEXA scans at the appropriate frequency before the service was established, versus 18 (82%) after the service was initiated. Seven (32%) patients were taking appropriate pharmacotherapy before the service, versus 17 (77%) after the service. Nine (41%) patients were taking calcium and vitamin D before the service, versus 22 (100%) after the service. Three (33%) of these patients were taking the appropriate dose and salt of calcium before the service, versus 20(91%) after the service. Five (56%) of the 9 patients were taking the appropriate vitamin D dose before the service, versus 21 (95%) after the service. No patient had documented nonpharmacologic education prior to the service, compared with all patients after the service. All differences were significant (p < 0.05). Conclusions: A pharmacist-run osteoporosis service significantly improved short-term compliance with guidelines, including appropriate DEXA scan frequency, pharmacotherapy, calcium and vitamin D supplementation, and nonpharmacologic education.
X-Ray Fluorescence Analysis of the Light Elements in Rocks and Minerals
Authors: Rose Harry J. , Adler Isidore , Flanagan Francis J. 
Published: October 2009

Recent advances in the x-ray fluorescence analysis of the light elements offer the advantage of speed and an accuracy approaching that of wet chemical procedures In addition to Fe, Mn, Ti, Ca, and K, the elements P, Si, Al, and Mg, previously considered too light to be determined quantitatively, can now be included in the scheme of analysis X-ray fluorescence analysis of these light elements is primarily confined to layers close to the surface, with the attendant problems of particle size, mineralogic history, and absorption differences owing to compositional variation among samples Fusion of the sample with a suitable flux eliminates problems of particle size and mineralogic differences Simple fusion, however, does not eliminate absorption differences due to variation in matrix By introducing into the fusion melt a strong absorber (La2O3) for the light elements, the variation in concentration of absorbing elements in the unknown sample will not materially affect the overall absorption of the fused mass for the elements being determined This permits the use of a single set of standards regardless of the rock type to be analyzed The x-ray fluorescence method has been applied to the analysis of a wide variety of rock types such as granite, diabase, dunite, limestone, dolomite, and phosphate rock, with results that compare favorably with chemical values
The Infrared Spectra of Some Acenaphthenes, Biphenyls, Fluorenes, Indans, Naphthalenes, and Tetralins
Authors: Hume Janis M. , Jenkins Gilbert I. 
Published: October 2009

A systematic study has been made of all of the available infrared spectra of acenaphthenes, biphenyls, fluorenes, indans, naphthalenes and tetralins. Bar charts giving the wavelengths between 8 and 1 5 microns at which the bands occur in the spectrum of each compound and also their approximate intensities have been prepared for each of the six groups of compounds and spectral/structural correlations derived from them The correlations together with those already established for alkylbenzenes should be useful in the identification of aromatic hydrocarbons in petroleum fractions and other hydrocarbon mixtures Some acenaphthenes, fluorenes, and naphthalenes have also been examined in the 15 to 22 microns region.
Mechanisms of Interactions of Alkali and Alkaline Earth Elements in Flame Photometry
Authors: Johnson Russell W. , Schrenk W. G. 
Published: October 2009

Cationic interactions in flame photometry were investigated to study some of the factors that cause enhancements of spectral lines. Interactions of the alkali and alkaline earth metals in an oxygen-acetylene flame have indicated that several mechanisms may be responsible for enhancement Where conditions are proper, enhancements of emissions of cations may be a combination of at least three factors a) the effect of electron concentration from an easily ionized extraneous element on the ground state population of the test element, b) the effect of transfer of energy by radiation and c) the effect of transfer of energy due to collisions with excited atoms The effect of the electron concentration on the suppression of the ionization of the test element was the predominant mechanism by which enhancement occurred in most systems studied. However, in the study of the effect of potassium on rubidium direct evidence was obtained of excitation by transfer of radiant energy Indirect evidence of enhancement due to transfer of energy by collision also was observed in the same system.
Die Entstehung des periphrastischen Perfekts mit haben und sein im Deutschen – eine längst beantwortete Frage?
Authors: Öhl Peter 
Published: October 2009

Abstract
The rise of the periphrastic perfect tenses – past participle + have or be – is a phenomenon for which the analysis is especially promising with regards to the research on grammaticalisation. Firstly, it involved several steps of syntactic reanalysis and lexical recategorisation leading to a construction-specific auxiliary verb form. This allows for conclusions to be drawn about processes involved in grammaticalisation in general. Secondly, it is a grammatical change in which both Germanic and Romance languages converged. This allows for conclusions about universal conditions underlying such kinds of change. Thirdly, in German, the rise occurred rather late and within a relatively short period of time. This allows for the observation of the periphrasis in statu nascendi. In this paper, the grammaticalisation process is modeled and explained in a formal framework of generative syntax, also taking into account performance-based changes and contextual aspects providing the conditions for the relevant changes in the grammar. The main claim is that this process of grammaticalisation was terminated by an abrupt parametric change, leading to a syntactically reanalysed form of analytic inflection and the recategorisation of have as an auxiliary. The result was a full paradigm of periphrastic perfect tense. The preconditions for this grammatical change were provided by a sequence of performance-based changes and minor formal reanalyses, giving the process its gradual nature.
Diversity of the Arabidopsis Mitochondrial Genome Occurs via Nuclear-Controlled Recombination Activity
Authors: Arrieta-Montiel Maria P , Shedge Vikas , Davila Jaime , Christensen Alan C , Mackenzie Sally A 
Published: October 2009

Abstract
The plant mitochondrial genome is recombinogenic, with DNA exchange activity controlled to a large extent by nuclear gene products. One nuclear gene, MSH1, appears to participate in suppressing recombination in Arabidopsis at every repeated sequence ranging in size from 108 to 556 bp. Present in a wide range of plant species, these mitochondrial repeats display evidence of successful asymmetric DNA exchange in Arabidopsis when MSH1 is disrupted. Recombination frequency appears to be influenced by repeat sequence homology and size, with larger size repeats corresponding to increased DNA exchange activity. The extensive mitochondrial genomic reorganization of the msh1 mutant produced altered mitochondrial transcription patterns. Comparison of mitochondrial genomes from the Arabidopsis ecotypes C24, Col-0, and Ler suggests that MSH1 activity accounts for most or all of the polymorphisms distinguishing these genomes, producing ecotype-specific stoichiometric changes in each line. Our observations suggest that MSH1 participates in mitochondrial genome evolution by influencing the lineage-specific pattern of mitochondrial genetic variation in higher plants.
Disaster Preparedness in Pediatric Type 1 Diabetes Mellitus
Authors: Renukuntla Venkat S. , Hassan Krishnavathana , Wheat Suzanne , Heptulla Rubina A. 
Published: October 2009

OBJECTIVE: The goal was to assess emergency preparedness among families caring for children with type 1 diabetes mellitus.
METHODS: A total of 115 English-speaking families caring for children with type 1 diabetes mellitus who were attending the diabetes clinic at Texas Children's Hospital agreed to a questionnaire study designed to ascertain their level of preparedness for a disaster or emergency. The study was conducted from June through September 2008 and ended just before Hurricane Ike made landfall.
RESULTS: Families were better prepared for self-management of diabetes, compared with general disaster preparedness. Sixty-two percent of the families were generally unprepared for a major disaster. For self-management of diabetes specifically, however, 75% of families had adequate supplies to maintain care for 3 days. Families in higher and moderate socioeconomic status strata were better equipped for an emergency (P &lt; .002). Preparedness was found to be independent of age, gender, ethnicity, and previous experience of a disaster.
CONCLUSION: Disaster preparedness still lags in families of lower socioeconomic status.
Audio-Recorded Guided Imagery Treatment Reduces Functional Abdominal Pain in Children: A Pilot Study
Authors: van Tilburg Miranda A.L. , Chitkara Denesh K. , Palsson Olafur S. , Turner Marsha , Blois-Martin Nanette , Ulshen Martin , Whitehead William E. 
Published: October 2009

OBJECTIVE: This study was designed to develop and to test a home-based, guided imagery treatment protocol, using audio and video recordings, that is easy for health care professionals and patients to use, is inexpensive, and is applicable to a wide range of health care settings.
METHODS: Thirty-four children, 6 to 15 years of age, with a physician diagnosis of functional abdominal pain were assigned randomly to receive 2 months of standard medical care with or without home-based, guided imagery treatment. Children who received only standard medical care initially received guided imagery treatment after 2 months. Children were monitored for 6 months after completion of guided imagery treatment.
RESULTS: All treatment materials were reported to be self-explanatory, enjoyable, and easy to understand and to use. The compliance rate was 98.5%. In an intention-to-treat analysis, 63.1% of children in the guided imagery treatment group were treatment responders, compared with 26.7% in the standard medical care–only group (P = .03; number needed to treat: 3). Per-protocol analysis showed similar results (73.3% vs 28.6% responders). When the children in the standard medical care group also received guided imagery treatment, 61.5% became treatment responders. Treatment effects were maintained for 6 months (62.5% responders).
CONCLUSION: Guided imagery treatment plus medical care was superior to standard medical care only for the treatment of abdominal pain, and treatment effects were sustained over a long period.
Intimate Partner Violence and Death Among Infants and Children in India
Authors: Ackerson Leland K. , Subramanian S. V. 
Published: October 2009

OBJECTIVE: The goal was to test the association between maternal intimate partner violence (IPV) victimization and child death.
METHODS: Information was collected regarding 39096 children &lt;60 months of age in the nationally representative 2005–2006 National Family Health Survey of India. The exposures were maternal reports of physical, sexual, psychological, and any IPV. Outcomes included infant (0 to &lt;12 months), older child (12 to &lt;60 months), and any child (0 to &lt;60 months) deaths.
RESULTS: Maternal experience of physical IPV was associated with increased mortality rates among all children (risk ratio [RR]: 1.21 [95% confidence interval [CI]: 1.13–1.30]), infants (RR: 1.24 [95% CI: 1.01–1.53]), and older children (RR: 1.25 [95% CI: 1.00–1.56]). Sexual and psychological IPV were less strongly associated with child death. The associations between maternal IPV and death did not differ according to the child's gender.
CONCLUSION: The robust association between exposure to household IPV and infant and child death could be attributable to the mother's inability to care for her child, psychological stress associated with witnessing violence, and the use of maternal violence victimization as a proxy for child violence victimization.
Growth and low temperature photoluminescence of silicon nanowires for different catalysts
Authors: Demichel Olivier , Oehler Fabrice , Calvo Vincent , Noé Pierre , Besson Adrien , Pauc Nicolas , Gentile Pascal , Baron Thierry , Magnea Noël 
Published: October 2009

AbstractWe report the growth of silicon nanowires (SiNWs) by chemical vapor deposition (CVD) with several catalysts. We performed low temperature photoluminescence (PL) experiments on as-grown SiNWs for the following catalysts: Au, Cu, TiSi, PdSi and PtSi. Nanowires are chemically treated with an aqua regia solution to remove the catalyst droplets, this step is followed by a thermal oxidation process. We compared the PL of as-grown and processed SiNWs for each catalyst.
Using CAD-CAM Technology for the Full-Mouth, Fixed, Retrievable Implant Restoration: A Clinical Report
Authors: Piermatti Jack 
Published: October 2009

Abstract
Computer-assisted design (CAD) and computer-assisted manufacture (CAM) are technologic advancements used in dentistry today. These technologies have been developed to fabricate a complete arch substructure from a solid piece of titanium for a fixed, screw-retained implant-supported prosthesis. This clinical report demonstrates a treatment approach which uses CAD-CAM technology to incorporate a milled, titanium framework with retrievable metal ceramic crowns.
Evaluation of Zooplankton in Hatchery Diets for Channel Catfish Fry
Authors: Mischke Charles C , Wise David J , Byars Todd S 
Published: October 2009

Abstract
The efficacy of zooplankton as a supplemental hatchery diet for fry of channel catfish Ictalurus punctatus was evaluated. When a commercial diet is used as a reference, fry fed exclusively on zooplankton—either live or dried—performed poorly in their growth rate. However, when live or dried zooplankton were fed to fry in conjunction with the commercial diet, fry weight increased 40–50% over the weight of fry fed the commercial diet alone in a 19-d feeding trial. Data from this study indicate that zooplankton may serve as a sustainable and reliable supplement during hatchery production. These data also reaffirm the importance of zooplankton as a feed source in the growth of channel catfish fry. Zooplankton are important in catfish fry culture, and when zooplankton are present with commercial diets, improved growth results. Based on results of this study, supplemental feeding of zooplankton to hatchery fry and managing fry ponds for increased zooplankton densities should increase fry growth during the nursery phase of culture.
Comparative Swimming Performance of Juvenile Blue Catfish and Hybrid Catfish
Authors: Beecham Rachel Venn , Minchew C Douglas , Parsons Glenn R , LaBarre Susan B 
Published: October 2009

Abstract
We compared the swimming performance of juvenile blue catfish Ictalurus furcatus and hybrid catfish (female channel catfish I. punctatus × male blue catfish) using a protocol in which fish were forced to swim at a fixed velocity and their time to fatigue recorded at speeds of 30–120 cm/s. Hybrid catfish swam significantly longer than blue catfish at all of the speeds tested except 30 and 40 cm/s. The maximum sustained swimming speed (no fatigue in times ≥200 min) was 30 and 40 cm/s for blue catfish and hybrid catfish, respectively. The maximum prolonged swimming speed (fatigue in times &gt;20 s but &lt;200 min) was 100 cm/s for blue catfish and 120 cm/s for hybrid catfish. The burst swimming speed (fatigue in times &lt;20 s) for blue catfish was 110 cm/s. The burst swimming speed for hybrid catfish was not determined; however, it is higher than its maximum prolonged swimming speed of 120 cm/s (highest speed tested). Hybrid catfish were able to swim longer before fatiguing than were blue catfish at 50 cm/s (156 versus 97 min) and at 60 cm/s (33 versus 6 min). Both blue catfish and hybrid catfish fatigued in less than 5 min at 70 cm/s, less than 3 min at 80 cm/s, and less than 60 s at 110 cm/s. No blue catfish swam at 120 cm/s while hybrids swam for 26 s at that speed. The results of this study will help fish producers understand the relationship between the speed of water currents produced by various aeration equipment and fatigue in pond-raised blue and hybrid catfish fingerlings.
Characterization of Red Drum Microsatellite Markers in Spotted Seatrout
Authors: Renshaw Mark A , Gawriluk Tom R , Gold John R 
Published: October 2009

Abstract
Polymerase chain reaction primers for a total of 132 nuclear-encoded microsatellites originally developed from genomic libraries for red drum Sciaenops ocellatus produced reliable and consistent amplifications in the closely related spotted seatrout Cynoscion nebulosus. Thirty-three of the primers amplified microsatellites that were monomorphic among a sample of 30 individuals, while 12 of the remaining 99 polymorphic loci exhibited possible null alleles. This provides a set of 87 microsatellite loci that will be highly useful in future genetic studies related to the stock enhancement and culture of spotted seatrout. Spotted seatrout comprise an important recreational fishery in the bays and estuaries in U.S. waters of the Gulf of Mexico and western Atlantic Ocean, and stock enhancement via supplementation with hatchery-reared individuals is ongoing, planned, or under consideration in several southern states.