bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Rh(III)‐Catalyzed Direct C—H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile.
Authors: Rakshit Souvik , Grohmann Christoph , Besset Tatiana , Glorius Frank 
Published: June 2011

AbstractEither olefinated benzamides or tetrahydroisoquinolones are formed from the reaction of benzamides and alkenes, depending on the N‐substituents.
ChemInform Abstract: Sequencing Cross‐Metathesis and Non‐Metathesis Reactions to Rapidly Access Building Blocks for Synthesis.
Authors: Sirasani Gopal , Paul Tapas , Andrade Rodrigo B. 
Published: June 2011

AbstractThe cross‐metathesis reactions between various olefins can be sequenced with a series of non‐metathesis reactions, such as the Wittig and Horner—Wadsworth—Emmons olefination to access stereodefined dienoates, the hydride‐mediated reduction to give trans‐allylic alcohols, the Evans aldol reaction to prepare diastereomerically pure syn‐propionate aldols and the Brown allyl‐ and Roush crotylboration to yield enantioenriched homoallylic alcohols (to be continued).
ChemInform Abstract: Catalytic Batch and Continuous Flow Production of Highly Enantioenriched Cyclohexane Derivatives with Polymer‐Supported Diarylprolinol Silyl Ethers.
Authors: Alza Esther , Sayalero Sonia , Cambeiro Xacobe C. , Martin‐Rapun Rafael , Miranda Pedro O. , Pericas Miquel A. 
Published: June 2011

AbstractThe known prolinol ether (Ia) and the new derivative (Ib) are tested in the enantioselective domino Michael—Knoevenagel reaction of aldehyde (II) with diester (III).
ChemInform Abstract: Superelectrophilic Iodination of Deactivated Arenes with Triiodoisocyanuric Acid.
Authors: da Ribeiro Rodrigo S. , Esteves Pierre M. , Mottos Marcio C. S. 
Published: June 2011

AbstractAn efficient and regioselective formation of iodoarenes (II), (IV), (VI), and (VIII) is presented.
ChemInform Abstract: Palladium(II)—NHC Complexes Containing Benzimidazole Ligand as a Catalyst for C—N Bond Formation.
Authors: Dogan Oeznur , Demir Serpil , Oezdemir Ismail , Cetinkaya Bekir 
Published: June 2011

AbstractThe title palladium—NHC complexes efficiently catalyze the N‐arylation of primary anilines to give triarylamines in good yields.
ChemInform Abstract: Citric Acid Catalyzed Beckmann Rearrangement, under Solvent‐Free Conditions.
Authors: Thopate Shankar Ramchandra , Kote Satosh Rajaram , Rohokale Sandeep Vasantrao , Thorat Nitin Madhukar 
Published: June 2011

AbstractThe protocol provides short reaction times, an easy work‐up along with mostly high yields.
ChemInform Abstract: Activation of Vinyl Iodides for the Highly Enantioselective Addition to Aldehydes.
Authors: DeBerardinis Albert M. , Turlington Mark , Pu Lin 
Published: June 2011

AbstractVinylzinc reagents, generated in situ, undergo enantioselective addition to aldehydes to yield allylic alcohols in the presence of chiral catalyst ABN.
ChemInform Abstract: The Coupling of Arylboronic Acids with Nitroarenes Catalyzed by Rhodium.
Authors: Zheng Xingwang , Ding Jinchang , Chen Jiuxi , Gao Wenxiao , Liu Miaochang , Wu Huayue 
Published: June 2011

AbstractThe reaction tolerates a wide range of electron‐donating and withdrawing groups in both reaction partners.
ChemInform Abstract: Highly Efficient Suzuki—Miyaura Coupling of Aryl Tosylates and Mesylates Catalyzed by Stable, Cost‐Effective [1,3‐Bis(diphenylphosphino)propane]nickel(II) Chloride [Ni(dppp)Cl2] with only 1 mol% Loading.
Authors: Gao Han , Li You , Zhou Yi‐Guo , Han Fu‐She , Lin Ying‐Jie 
Published: June 2011

AbstractA highly effective, inexpensive catalyst for the Suzuki—Miyaura cross coupling, namely NiCl2(dppp), is presented.
ChemInform Abstract: The Polyethylene Glycol—Sodium Dodecylsulfate—PdCl2—Water Supramolecular Catalytic System for the Suzuki Reaction.
Authors: Ibragimova Alsu I. , Vagapova Guzalia I. , Gainanova Gulnara A. , Syakaev Victor V. , Zakharov Valery M. , Rizvanov Ildar Kh. , Zakharova Lucia Ya. , Latypov Shamil K. , Konovalov Alexander I. 
Published: June 2011

AbstractThe catalytic system can be reused with only a small loss of activity.
ChemInform Abstract: H3PW12O40‐Catalyzed Alkylation of Arenes and Diveratrylmethanes: Convenient Routes to Triarylmethanes and to Symmetrical and Unsymmetrical 9,10‐Diaryl‐2,3,6,7‐tetramethoxyanthracenes.
Authors: Mohammadpoor‐Baltork Iraj , Moghadam Majid , Tangestaninejad Shahram , Mirkhani Valiollah , Mohammadiannejad‐Abbasabadi Kazem , Khavasi Hamid R. 
Published: June 2011

AbstractAn efficient and green method for the solventless synthesis of triarylmethanes and difurylarylmethanes under thermal and microwave irradiation conditions in the presence of the reusable catalyst H3PW12O40 is developed.
ChemInform Abstract: Efficient and Chemoselective Methods for the Synthesis of Some Isobenzofuran and Spiro[isobenzofuran‐1,2′‐pyrrole] Derivatives.
Authors: Mohammadizadeh Mohammad R. , Firoozi Neda , Aradeh R. 
Published: June 2011

AbstractThe title compounds are obtained via oxidative cleavage of vicinal dihydroxyindenopyrrolones with lead tetraacetate.
ChemInform Abstract: Enantioselective Rhodium‐Catalyzed Allylic C—H Activation for the Addition to Conjugated Dienes.
Authors: Li Qian , Yu Zhi‐Xiang 
Published: June 2011

AbstractThe optimized conditions afford the cyclized products with moderate to good enantioselectivity in a highly diastereoselective manner (d.e < 90%).
ChemInform Abstract: Sequential One‐Pot Ruthenium‐Catalyzed Azide—Alkyne Cycloaddition from Primary Alkyl Halides and Sodium Azide.
Authors: Johansson Johan R. , Lincoln Per , Norden Bengt , Kann Nina 
Published: June 2011

AbstractIt allows a simple and practical access to various 1,2,3‐triazoles.
ChemInform Abstract: Synthesis of 6,8‐Diarylimino‐7H‐pyrano[3,2‐c:5,6‐c′]dicoumarins; Chemoselective Hydrolysis of the Ether‐ and Imino‐Functions.
Authors: Maiti Sourav , Panja Suman Kalyan , Bandyopadhyay Chandrakanta 
Published: June 2011

AbstractIf compound (II) is treated with glacial acetic acid under reflux conditions the original starting material (I) is regenerated.
ChemInform Abstract: Oxidation of 1‐Benzyldihydroisoquinolines or 1‐Benzyltetrahydroisoquinolines with Dioxygen to 1‐Benzoylisoquinolines.
Authors: Gan Haifeng , Lu Yunyu , Huang Yue , Ni Lijun , Xu Jinyi , Yao Hequan , Wu Xiaoming 
Published: June 2011

AbstractA mild process is developed with molecular oxygen as the sole oxidant to furnish 1‐benzoylquinolines as synthons of natural products and pharmaceuticals.
ChemInform Abstract: Fused Phenanthridines: Domino Cyclization of 1,6‐Diynes with Bromo(iso)quinoline.
Authors: Hu Yimin , Sun Yongjie , Hu Jiping , Zhu Tao , Yu Tao , Zhao Quansheng 
Published: June 2011

AbstractA practical and efficient domino method for the synthesis of fused phenanthridines is developed.
ChemInform Abstract: One‐Pot Multistep Synthesis of 3‐Aminoindolizine Derivatives.
Authors: Li Lianhai , Chua Waepril Kimberly S. 
Published: June 2011

AbstractVarious 2‐carbonyl substituted pyridines react with nitriles (II) in the presence of Hantzsch ester as a mild hydride transfer reagent and pyridinium acetate as the catalyst to give the medicinally important target structures.
ChemInform Abstract: Synthesis, Hypoxia‐Selective Cytotoxicity of New 3‐Amino‐1,2,4‐benzotriazine‐1,4‐dioxide Derivatives.
Authors: Xia Qing , Zhang Ling , Zhang Jun , Sheng Rong , Yang Bo , He Qiaojun , Hu Yongzhou 
Published: June 2011

AbstractCompounds (V b), (V d) and (V e) exhibit the same or higher cytotoxic activities against K562 and SMMC‐7721 cell lines compared to tirapazamine.
ChemInform Abstract: Nano Fe3O4 as Magnetically Recyclable Catalyst for the Synthesis of α‐Aminophosphonates in Solvent‐Free Conditions.
Authors: Reddy B. V. Subba , Krishna A. Siva , Ganesh A. V. , Kumar G. G. K. S. Narayana 
Published: June 2011

AbstractThree component condensation of aldehydes or ketones with amines and diethylphosphite in high yields and short reaction times affords the biologically important target compounds.
ChemInform Abstract: A Concise Total Synthesis of (.+‐.)‐Cipadonoid B from Synthetic Azedaralide.
Authors: Faber Jonathan M. , Williams Craig M. 
Published: June 2011

AbstractA ketal Claisen rearrangement is utilized to build up the tetranortriterpene cipadonoid B (III) from azedaralide (II) in a one‐pot cascade reaction.
ChemInform Abstract: Improved Synthesis of 5‐Hydroxymethyl‐2′‐deoxycytidine Phosphoramidite Using a 2′‐Deoxyuridine to 2′‐Deoxycytidine Conversion Without Temporary Protecting Groups.
Authors: Hansen Anders S. , Thalhammer Armin , El‐Sagheer Afaf H. , Brown Tom , Schofield Christopher J. 
Published: June 2011

AbstractAn improved strategy for the synthesis of protected 5‐hydroxymethyl‐2′‐deoxycytidine phosphoramidite (XI), useful for site‐specific incorporation into oligonucleotides, is described.
Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection
Authors: Pyrgaki Christina , Bannister Steve J. , Gera Lajos , Gerber John G. , Gal Joseph 
Published: June 2011

AbstractItraconazole is an antifungal drug widely used in a variety of fungal infections, which have become a significant public‐health problem in recent decades. Itraconazole is a chiral drug consisting of two diastereoisomeric racemates, i.e., four stereoisomers. Data in the literature suggests that stereochemistry may play a significant role in the action and disposition of the drug and therefore stereoselective analytical methods for the determination of the drug in biological fluids are needed for the elucidation of that role. We report a stereoselective HPLC method that incorporates solvent extraction, the use of an internal standard, two chiral stationary phases in series, and fluorescence detection. The procedure is enantioselective and partially diastereoselective and provides the concentrations in blood plasma of the two epimer mixtures 2R,4S,2'R/2R,4S2'S and 2S,4R,2'R/2S,4R,2'S, respectively, each of which is a combination of the two epimers that differ in the configuration at the sec‐butyl group. The analytical method has suitable sensitivity, recovery, precision, and accuracy. Analysis of the plasma of a human subject six hours after the oral administration of a single 200‐mg dose of itraconazole showed a 3.4‐fold difference between the concentrations of the epimer mixtures. The method has certain advantages over the published alternative procedure that uses LC‐MS. Chirality 2011. © 2011 Wiley‐Liss, Inc.
Kupfer
Authors: Schwedt Georg 
Published: June 2011

AbstractDas seit fast 200 Jahren bestehende Mineralogische Museum der Universität Bonn, das 1874 eine bedeutende Sammlung vom Gründer des heutigen Rheinischen Mineralien‐Kontors A. Krantz erhielt, zeigt unter anderem systematisch geordnet Minerale zu ausgewählten chemischen Elementen. Sie werden in dieser Serie zum Internationalen Jahr der Chemie 2011 näher vorgestellt.
Oxime‐Based Click Chemistry in the Development of 3‐Isoxazolecarboxylic Acid Containing Inhibitors of Yersinia pestis Protein Tyrosine Phosphatase, YopH
Authors: Bahta Medhanit , Burke Terrence R. 
Published: June 2011

AbstractThe pathogenicity of Yersinia pestis relies on several effector proteins including YopH, a protein tyrosine phosphatase (PTP). We previously screened a library of analogues based on the ubiquitous PTP substrate para‐nitrophenylphosphate (pNPP) and found that incorporation of a 3‐phenyl substituent to give 6‐nitro‐[1,1′‐biphenyl]‐3‐yldihydrogen phosphate (1) enhanced affinity. Herein we report the conversion of 1 from a substrate into an inhibitor by replacing the hydrolysable phosphoryl group with a 3‐isoxazolecarboxylic acid moiety and by introduction of an aminooxy group and subsequent diversification using oxime‐based click chemistry. This approach led to the identification of non‐promiscuous bidentate YopH inhibitors with affinity in the low micromolar range.
Evaluation of a scoring system for predicting lymph node malignancy in ultrasound guided fine needle aspiration practice
Authors: Wu Maoxin , Chen Hua , Zheng XiaoYong , Burstein David E. , Aisner Dara 
Published: June 2011

Ultrasound‐guided fine needle aspiration (USG‐FNA) has enabled cytopathologists to accurately diagnose smaller or non‐palpable lymph nodes (LN) on a regular basis. Pre‐FNA clinical and ultrasonographic factors, such as a patient's age, ratio of short to long axis diameter (S/L ratio), internal echogenicity, and the vascular pattern of a LN, are reported to be able to predict the benign or malignant nature of a LN. This study is designed to test the formula “0.06 × (age) + 4.76 × (S/L ratio) + 2.15 × (internal echo) + 1.80 × (vascular pattern)” generated from the study of Liao et al. as a scoring system for predicting LN malignancy in a cytopathologist operated USG‐FNA practice.Eighty‐three reports of USG‐FNA of LNs issued between 7/1/2008 and 4/28/2010 were reviewed. Patient's age, S/L ratio, internal echo, and vascular pattern were used to generate scores based on the aforementioned formula. A score of seven was used as a cutoff for predicting benign (<7) and malignant (>7) LNs. FNA cytology diagnosis, flow cytometric analysis as well as subsequent surgical diagnosis in some cases served as gold standard for statistical analysis.Among 46 USG‐FNA of LNs with scores > 7, 38 were malignant and eight were benign. All 37 USG‐FNA of LNs with scores < 7 were proven to be benign. The scoring system achieved 100% sensitivity, 82% specificity, 83% positive predictive value, 100% negative predictive value, and 90% accuracy. Further study of the eight “false‐positive” cases revealed that three of them (37.5%) were found to be malignant in follow‐up FNA and/or surgical biopsy.This scoring system may serve as a complementary tool in determining how aggressive a FNA procedure should be performed, how a FNA sample of LN should be triaged for ancillary study, and how closely a patient with lymphadenopathy should be followed up. Diagn. Cytopathol. 2013;41:1100–1106. © 2011 Wiley Periodicals, Inc.
Division of labor between subsets of lymph node dendritic cells determines the specificity of the CD8+ T‐cell recall response to influenza infection
Authors: Suárez‐Ramírez Jenny E. , Wu Tao , Lee Young‐Tae , Aguila Carolina C. , Bouchard Keith R. , Cauley Linda S. 
Published: June 2011

AbstractCytotoxic T lymphocytes (CTLs) are important targets for vaccines against a wide variety of infections that enter the body via mucosal tissues. To induce effective immunity these vaccines must include the most protective epitopes and elicit rapid recall responses at the site of infection. Although live attenuated viruses are sometimes used to induce cellular immunity against recurrent influenza infections, the mechanisms that determine the magnitude of the response to individual viral components are very poorly defined. Heterosubtypic infections in C57BL/6 mice illustrate an additional level of complexity, when the antigen specificity of the response shifts dramatically between primary and secondary challenge. This model provides a unique opportunity to identify the mechanisms that regulate memory CD8+ T‐cell reactivation in vivo and control the specificity of the recall response by pathogen‐specific CTL. We show that multiple factors contribute to the changing pattern of immunodominance during secondary infection, including the location of the memory CD8+ T cells at the time of reinfection and their ability to directly recognize migratory CD103+ DCs as they arrive in the lung draining LN.
Novel Quinidine‐Derived Organocatalysts for the Asymmetric Substitutions of O‐Boc‐Protected Morita–Baylis–Hillman Adducts
Authors: Pei Cheng‐Kui , Zhang Xiu‐Chun , Shi Min 
Published: June 2011

AbstractA series of novel quinidine‐derived organocatalysts was synthesized and utilized for the asymmetric substitution of O‐Boc‐protected Morita–Baylis–Hillman adducts with various carbamates and tosylcarbamates, affording the corresponding products in good to high yields (up to 91 % yield) with moderate to high ee values (up to 96 % ee) under mild conditions.
A novel approach to the electrical safety of low‐voltage installations: the TN‐Island grounding system
Authors: Parise Giuseppe , Mitolo Massimo 
Published: June 2011

SUMMARYTN‐Island grounding system is an effective way to both protect persons from shock hazard in installations with limited demand load and greatly limit electrical interferences among systems. This distribution system, which utilizes separation transformers, grounded on the secondary sides, allows one to supply loads broken into “islands” as independent electrical areas. TN‐Island fits best the supply of electrical installations in particular locations like moored pleasure crafts in marinas, fish farms, fish tanks, refrigerated containers in seaports, data centers, and construction sites. Additionally, by introducing the TN‐Island to provide power to dwelling units, regardless of their existing electrical distribution system, we can improve electrical safety and, at the same time, increase reliability since the “islands” are not electrically interfering with each other. Last but not least, the TN‐Island system, allows one to develop “hybrid” systems just for restricted electrical areas, for example, dwelling units, and can lead to a free choice of systems and standards (i.e., NEC‐USA and IEC‐UE). This would eliminate technical obstacles and discourage market barriers. Such a process is as crucial as it is inevitable, as a consequence of the current world globalization. This could promote electrical safety, better functionality, and lower costs. Copyright © 2011 John Wiley & Sons, Ltd.
A high order spectral volume solution to the Burgers' equation using the Hopf–Cole transformation
Authors: Kannan Ravi , Wang Z.J. 
Published: June 2011

SUMMARYA limiter free high order spectral volume (SV) formulation is proposed in this paper to solve the Burgers' equation. This approach uses the Hopf–Cole transformation, which maps the Burgers' equation to a linear diffusion equation. This diffusion equation is solved in an SV setting. The local discontinuous Galerkin (LDG) and the LDG2 viscous flux discretization methods were employed. An inverse transformation was used to obtain the numerical solution to the Burgers' equation. This procedure has two advantages: (i) the shock can be captured, without the use of a limiter; and (ii) the effects of SV partitioning becomes almost redundant as the transformed equation is not hyperbolic. Numerical studies were performed to verify. These studies also demonstrated (i) high order accuracy of the scheme even for very low viscosity; (ii) superiority of the LDG2 scheme, when compared with the LDG scheme. In general, the numerical results are very promising and indicate that this procedure can be applied for obtaining high order numerical solutions to other nonlinear partial differential equations (for instance, the Korteweg–de Vries equations) which generate discontinuous solutions. Copyright © 2011 John Wiley & Sons, Ltd.
Alumina–Carbon Nanofibers Nanocomposites Obtained by Spark Plasma Sintering for Proton Exchange Membrane Fuel Cell Bipolar Plates
Authors: Borrell A. , Torrecillas R. , Rocha V. G. , Fernández A. 
Published: June 2011

AbstractThere is an increasing demand of multifunctional materials for a wide variety of technological developments. Bipolar plates for proton exchange membrane fuel cells are an example of complex functionality components that must show among other properties high mechanical strength, electrical, and thermal conductivity. The present research explored the possibility of using alumina–carbon nanofibers (CNFs) nanocomposites for this purpose. In this study, it was studied for the first time the whole range of powder compositions in this system. Homogeneous powders mixtures were prepared and subsequently sintered by spark plasma sintering. The materials obtained were thoroughly characterized and compared in terms of properties required to be used as bipolar plates. The control on material microstructure and composition allows designing materials where mechanical or electrical performances are enhanced. A 50/50 vol.% alumina–CNFs composite appears to be a very promising material for this kind of application.
The caranto paleosol and its role in the early urbanization of Venice
Authors: Donnici Sandra , Serandrei‐Barbero Rossana , Bini Claudio , Bonardi Maurizio , Lezziero Alberto 
Published: June 2011

AbstractAs rising sea level threatens Venice, there is a need to construct a historical framework for interpreting modern environmental changes. Environmental conditions that would later help support Venice's urbanization were established during the Late Glacial period when calcic soils began to develop in the Venetian alluvial paleoplain. A calcic paleosol, buried by Middle to Late Holocene marine transgressive deposits, represents a subsurface layer long known in the Venice area as “caranto.” Referenced in the ancient chronicles of architects and builders, the caranto exhibits relatively high compressive and shear strength, making it an important substrate for supporting building foundations, some dating back to the Gothic era (12th–15th centuries A.D.). Hence, the caranto paleosol documents local post‐glacial environmental changes while playing an important role in Venetian building construction and human settlement. Here we provide geochemical, sedimentological, paleoecological, and chronological analyses of the caranto paleosol and related deposits based on recent coring of the Venetian Lagoon. © 2011 Wiley Periodicals, Inc.
Mesenchymal stem cell seeding promotes reendothelialization of the endovascular stent
Authors: Wu Xue , Wang Guixue , Tang Chaojun , Zhang Dechuan , Li Zhenggong , Du Dingyuan , Zhang Zhengcai 
Published: June 2011

AbstractThis study is designed to make a novel cell seeding stent and to evaluate reendothelialization and anti‐restenosis after the stent implantation. In comparison with cell seeding stents utilized in previous studies, Mesenchymal stem cells (MSCs) have advantages on promoting of issue repair. Thus it was employed to improve the reendothelialization effects of endovascular stent in present work. MSCs were isolated by density gradient centrifugation and determined as CD29+CD44+CD34− cells by immunofluorescence and immunocytochemistry; gluten and polylysine coated stents were prepared by ultrasonic atomization spray, and MSCs seeded stents were made through rotation culture according to the optimized conditions that were determined in previous studies. The results from animal experiments, in which male New Zealand white rabbits were used, show that the reendothelialization of MSCs coated stents can be completed within one month; in comparison with 316L stainless steel stents (316L SS stents) and gluten and polylysine coated stents, the intimal hyperplasia and in‐stent restenosis are significantly inhibited by MSCs coated stents. Endovascular stent seeded with MSCs promotes reendothelialization and inhibits the intimal hyperplasia and in‐stent restenosis compared with the 316L SS stents and the gluten and polylysine coated stents. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: , 2011.