bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leading causes of death in Vietnamese Americans: An ecological study based on national death records from 2005–2020
Authors: Tran Khoa , Shon HyeYuong , Phan Jonathan , Cheng Tina , Kim Gloria S. , Jamal Armaan , Srinivasan Malathi , Palaniappan Latha P. , Nguyen Linda , Huang Robert J. 
Published: May 2024

Background
Disaggregated data is a cornerstone of precision health. Vietnamese Americans (VietAms) are the fourth-largest Asian subgroup in the United States (US), and demonstrate a unique burden of disease and mortality. However, most prior studies have aggregated VietAms under the broader Asian American category for analytic purposes. This study examined the leading causes of death among VietAms compared to aggregated Asian Americans and non-Hispanic Whites (NHWs) during the period 2005–2020.

Methods
Decedent data, including underlying cause of death, were obtained from the National Center for Health Statistics national mortality file from 2005 to 2020. Population denominator estimates were obtained from the American Community Survey one-year population estimates. Outcome measures included proportional mortality, age-adjusted mortality rates per 100,000 (AMR), and annual percent change (APC) in mortality over time. Data were stratified by sex and nativity status. Due to large differences in age structure, we report native- and foreign-born VietAms separately.

Findings
We identified 74,524 VietAm decedents over the study period (71,305 foreign-born, 3,219 native-born). Among foreign-born VietAms, the three leading causes of death were cancer (26.6%), heart disease (18.0%), and cerebrovascular disease (9.0%). Among native-born VietAms the three leading causes were accidents (19.0%), self-harm (12.0%), and cancer (10.4%). For every leading cause of death, VietAms exhibited lower mortality compared to both aggregated Asians and NHWs. Over the course of the study period, VietAms witnessed an increase in mortality in every leading cause. This effect was mostly driven by foreign-born, male VietAms.

Conclusions and relevance
While VietAms have lower overall mortality from leading causes of death compared to aggregated Asians and NHWs, these advantages have eroded markedly between 2005 and 2020. These data emphasize the importance of racial disaggregation in the reporting of public health measures.
Eligibility for omecamtiv mecarbil in a real-world heart failure population: Data from the Swedish Heart Failure Registry
Authors: Lindberg Felix , Øigaard Natanael , Metra Marco , Rosano Giuseppe M. C. , Dahlström Ulf , Mol Peter , Hage Camilla , Lund Lars H. , Savarese Gianluigi 
Published: May 2024

Aims
We assessed eligibility for omecamtiv mecarbil (OM) in a real-world cohort with heart failure with reduced ejection fraction (HFrEF) according to the selection criteria of the GALACTIC-HF trial (trial scenario) and selected trial´s criteria more likely to impact real-world use (pragmatic scenario).

Methods and results
We included 31,015 patients with HFrEF lasting ≥3 months and registered in the Swedish HF registry between 2000–2021. Trial eligibility was calculated by applying all the GALACTIC-HF selection criteria. The pragmatic scenario considered only the New York Heart Association class, history of worsening HF, N-terminal pro-B-type natriuretic peptides (NT-proBNP), blood pressure and renal failure criteria defined as in the trial. Eligibility for OM in chronic HFrEF was 21% and 36% in the trial and pragmatic scenarios, respectively. Eligibility was higher in those with EF<30% (trial: 27%, pragmatic: 44%), in-patients (trial:30%, pragmatic:57%), severe HF (trial: 35%, pragmatic: 60%), NYHA class III-IV (trial: 26%, pragmatic: 45%), and NT-proBNP≥5,000pg/mL (trial: 30%, pragmatic: 51%). The criteria that most limited eligibility were history of a recent worsening HF event (60% eligible in chronic HFrEF), elevated NT-proBNP (82% eligible), and deviating blood pressure (82% eligible). Overall, eligible patients were characterized by more severe HF and higher CV event-rates in both scenarios, and higher comorbidity burden in the pragmatic scenario.

Conclusion
Approximately 21% of real-world chronic HFrEF patients would be eligible for OM according to the GALACTIC-HF selection criteria, and 36% according to the criteria more likely to affect OM use in clinical practice. Criteria in both scenarios identified a patient-group with severe HF and high CV event-rates.
Validation of a Cantonese Version of the Amsterdam-Nijmegen Everyday Language Test (CANELT): A functional approach
Authors: Wong Winsy Wing Sze 
Published: May 2024

Background
The current study aimed to validate the Cantonese version of the Amsterdam-Nijmegen Everyday Language Test (CANELT), a functional communication assessment tool for Cantonese speakers with aphasia. A quantitative scoring method was adopted to examine the pragmatics and informativeness of the production of people with aphasia (PWA).

Method
CANELT was translated from its English version with cultural adaptations. The performance on the 20-item CANELT collected from 56 PWA and 100 neurologically healthy Cantonese-speaking controls aged 30 to 79 years was orthographically transcribed. Scoring was based on the completeness of the main concepts produced in the preamble and subsequent elaborations, defined as Opening (O) and New Information (NI). Measures examining the validity and reliability were conducted.

Results
An age effect was found in neurologically healthy controls, and therefore z scores were used for subsequent comparisons between neurologically healthy controls and PWA. The test showed strong evidence for known-group validity in both O [χ2 (2) = 95.2, p < .001] and NI [χ2 (2) = 100.4, p < .001]. A moderate to strong correlation was found between CANELT and standardized aphasia assessment tools, suggesting satisfactory concurrent validity. Reliability measures were excellent in terms of internal consistency (Cronbach’s α of .95 for both ‘O’ and ‘NI’), test-retest reliability (ICC = .96; p < .001), intra-rater reliability (ICC = 1.00; p < .001), and inter-rater reliability for O (ICC = .99; p < .001) and NI (ICC = .99; p < .001). Sensitivity and specificity for O are 97% and 76.8%, respectively, while for NI, a sensitivity of 95% and specificity of 91.1% were obtained.

Conclusions
Measures on validity and reliability yielded promising results, suggesting CANELT as a useful and reliable functional communication assessment for PWA. Its application in managing PWA and potential areas for development are discussed.
Value of Sonazoid-enhanced ultrasonography in characterizing indeterminate focal liver lesions on gadoxetic acid-enhanced liver MRI in patients without risk factors for hepatocellular carcinoma
Authors: Ban Ji Yoon , Kang Tae Wook , Jeong Woo Kyoung , Lee Min Woo , Park Boram , Song Kyoung Doo 
Published: May 2024

Purpose
To evaluate the added value of contrast-enhanced ultrasonography (CEUS) using Sonazoid in characterizing focal liver lesions (FLLs) with indeterminate findings on gadoxetic acid-enhanced liver MRI in patients without risk factors for hepatocellular carcinoma (HCC).

Methods
Patients who underwent CEUS using Sonazoid for characterizing indeterminate FLLs on gadoxetic acid-enhanced liver MRI were. The indeterminate FLLs were classified according to the degree of malignancy on a 5-point scale on MRI and combined MRI and CEUS. The final diagnosis was made either pathologically or based on more than one-year follow-up. The diagnostic performance was assessed using a receiver operating characteristic (ROC) curve analysis, and the net reclassification improvement (NRI) was calculated.

Results
A total of 97 patients (mean age, 49 years ± 16, 41 men, 80 benign and 17 malignant lesions) were included. When CEUS was added to MRI, the area under the ROC curve increased, but the difference was not statistically significant (0.87 [95% confidence interval {CI}, 0.77–0.98] for MRI vs 0.93 [95% CI, 0.87–0.99] for CEUS added to MRI, P = 0.296). The overall NRI was 0.473 (95% CI, 0.100–0.845; P = 0.013): 33.8% (27/80) of benign lesions and 41.2% (7/17) of malignant lesions were appropriately reclassified, whereas 10.0% (8/80) of benign lesions and 17.6% (3/17) of malignant lesions were incorrectly reclassified.

Conclusions
Although performing CEUS with Sonazoid did not significantly improve the overall diagnostic performance in characterizing indeterminate FLLs on gadoxetic acid-enhanced liver MRI in patients without risk factors for HCC, it may increase radiologist’s confidence in classifying FLLs.
Women, Feminism and Italian Cinema: Archives from a Film Culture, Dalila Missero (2022)
Authors: Bonifazio Paola 
Published: May 2024

Review of: Women, Feminism and Italian Cinema: Archives from a Film Culture, Dalila Missero (2022)
Edinburgh: Edinburgh University Press, 200 pp.,
ISBN 978-1-47446-324-9, p/bk, £19.99
Anti-diabetic activity-guided isolation of α-amylase and α-glucosidase inhibitory terpenes from Capsella bursa-pastoris Linn.
Authors: Dar Mohd Akbar , Siddiqui Nasir A. , Mir Showkat R. , Akbar Seema , Mothana Ramzi A. , Masoodi Mubashir H. 
Published: May 2024

Abstract
The hypoglycaemic and hypolipidemic potential of ethanol extract of C. bursa-pastoris (ECbp) in streptozotocin (STZ)-provoked diabetic rats was evaluated, and compounds with their α-amylase and α-glucosidase inhibitory potential were isolated. Acute oral toxicity was evaluated in rats. Streptozotocin (STZ) (50 mg/kg body weight) was injected intraperitoneally into rats for diabetes induction. In diabetic rats, ECbp (0.2 g/kg b.w, p.o.) was administered orally for 21 days, and its outcome on blood glucose levels and body weight was observed on a weekly basis besides lipid profile. Compound isolation from ECbp was performed using column chromatography. Oral feeding of ECbp did not produce any toxic effects or death at a dose of 2,000 mg/kg body weight. A serum glucose reduction trend was observed in rats fed with glucose pre-treated with 200 mg/kg b.w. ECbp also appreciably (p < 0.001, p < 0.01, and p < 0.05) diminished raised blood glucose with decreased blood cholesterol levels and led to increased serum high-density lipoprotein levels in comparison to diabetic control rats. Body weight levels were considerably higher (p < 0.05) in diabetic rats treated with ECbp than in diabetic control rats. Isolation of two terpene derivatives (ECbp-1 and ECbp-2) was performed using ECbp, which exhibits significant α-amylase and α-glucosidase inhibition.
Massive fetal goiter treated by intra-amniotic injection of levothyroxine: a case report
Authors: Tamura Nami , Yamamoto Yuka , Takeda Jun , Ishigami Junpei , Suganuma Hiroki , Shimizu Toshiaki , Itakura Atsuo 
Published: May 2024

Abstract

Objectives
Fetal dyshormonogenetic goiter is a rare condition associated with perinatal complications and sequelae in infants. Although prenatal management remains controversial, further evidence is required for optimal management.

Case presentation
A 30-year-old pregnant woman with no history of thyroid disease was referred to our hospital with polyhydramnios. Fetal ultrasonography revealed fetal goiter. Cordocentesis revealed increased thyroid-stimulating hormone (TSH) and low levels of free thyroxine 4 (fT4), which was the basis of diagnosis of fetal hypothyroidism. Intra-amniotic injections of levothyroxine were administered, resulting in a reduction in the goiter size, amount of amniotic fluid, and level of maternal TSH. The mother was euthyroid during pregnancy. The infant was delivered vaginally at full term with a normal thyroid size and no respiratory disorders except hypothyroidism. At 2 years of age, her neurodevelopment is normal.

Conclusions
Intra-amniotic injections of levothyroxine for fetal hypothyroidism with massive goiter and polyhydramnios may improve perinatal outcomes.
Die bilingue Opfertafel der Tasuchion aus dem Fayum (Berlin, Ägyptisches Museum ÄM 11631)
Authors: Moje Jan , Gerhardt Marius 
Published: May 2024

Summary
Publication of an early Roman offering table for the woman Tasouchion. The table probably came from the Fayum and was inscribed with a rare bilingual Hieroglyphic-Greek inscription. The Hieroglyphic text contains a ritual, while the Greek text offers a Greek version of the well-known and wide-spread Latin epitaph sit tibi terra levis. Both texts are analyzed in the context of ancient funerary practices.
Neonatal and Obstetrical Outcomes of Pregnancies Complicated by Alloimmunization
Authors: Bahr Timothy M. , Tweddell Sarah M. , Zalla Jennifer M. , Dizon-Townson Donna , Ohls Robin K. , Henry Erick , Ilstrup Sarah J. , Kelley Walter E. , Ling Con Yee , Lindgren Peter C. , O’Brien Elizabeth A. , Christensen Robert D. 
Published: May 2024

BACKGROUND AND OBJECTIVES
Despite advances in the prevention of rhesus (Rh)(D) alloimmunization, alloantibodies to Rh(D) and non-Rh(D) red blood cell antigens continue to be detected in ∼4% of US pregnancies and can result in hemolytic disease of the fetus and newborn (HDFN). Recent reports on HDFN lack granularity and are unable to provide antibody-specific outcomes. The objective of this study was to calculate the frequency of alloimmunization in our large hospital system and summarize the outcomes based on antibody specificity, titer, and other clinical factors.

METHODS
We identified all births in a 6-year period after a positive red blood cell antibody screen result during pregnancy and summarized their characteristics and outcomes.

RESULTS
A total of 707 neonates were born after a positive maternal antibody screen result (3.0/1000 live births). In 31 (4%), the positive screen result was due to rhesus immune globulin alone. Of the 676 neonates exposed to alloantibodies, the direct antibody test (DAT) result was positive, showing antigen-positivity and evidence of HDFN in 37% of those tested. Neonatal disease was most severe with DAT-positive anti-Rh antibodies (c, C, D, e, E). All neonatal red blood cell transfusions (15) and exchange transfusions (6) were due to anti-Rh alloimmunization. No neonates born to mothers with anti-M, anti-S, anti-Duffy, anti-Kidd A, or anti-Lewis required NICU admission for hyperbilirubinemia or transfusion.

CONCLUSIONS
Alloimmunization to Rh-group antibodies continues to cause a majority of the severe HDFN cases in our hospital system. In neonates born to alloimmunized mothers, a positive DAT result revealing antigen-positivity is the best predictor of anemia and hyperbilirubinemia.
Implementasi Manajemen Strategis Pada Lembaga Wilayatul Hisbah Dalam Penegakan Syariat Islam di Kota Aceh
Authors: Chysara Daris Iqbal , Yuliani Yuliani , Rustandi Ridwan 
Published: May 2024

Aceh is an area that is given the authority to regulate and implement the law in accordance with Islamic law in the life of its own government. This study aims to find out and understand how the formulation of the Wilayatul Hisbah strategy in Banda Aceh City in the Enforcement of Islamic Law, Knowing the implementation of the Wilayatul Hisbah strategy in Banda Aceh City, and knowing the evaluation of strategies carried out by the Wilayatul Hisbah Institution of Banda Aceh City which is oriented towards the enforcement of Islamic law in Banda Aceh. The research method used is descriptive method with a qualitative approach. The formulation and implementation carried out by the Wilayatul Hisbah institution of Banda Aceh City has been carried out in accordance with the basic values of strategic management governance, quality and justice.
mTORc2 in Distal Convoluted Tubule and Renal K+ Excretion during High Dietary K+ Intake
Authors: Duan Xin-Peng , Zheng Jun-Ya , Jiang Shao-Peng , Wang Ming-Xiao , Zhang Chengbiao , Chowdhury Tanzina , Wang Wen-Hui , Lin Dao-Hong 
Published: May 2024

Key Points

High K stimulates mechanistic target of rapamycin complex 2 (mTORc2) in the distal convoluted tubule (DCT).Inhibition of mTORc2 decreased the basolateral Kir4.1/Kir5.1 and Na-Cl cotransporter in the DCT.Inhibition of mTORc2 of the DCT compromised kidneys' ability to excrete potassium during high K intake.

Background
Renal mechanistic target of rapamycin complex 2 (mTORc2) plays a role in regulating renal K+ excretion (renal-EK) and K+ homeostasis. Inhibition of renal mTORc2 causes hyperkalemia due to suppressing epithelial Na+ channel and renal outer medullary K+ (Kir1.1) in the collecting duct. We now explore whether mTORc2 of distal convoluted tubules (DCTs) regulates basolateral Kir4.1/Kir5.1, Na-Cl cotransporter (NCC), and renal-EK.

Methods
We used patch-clamp technique to examine basolateral Kir4.1/Kir5.1 in early DCT, immunoblotting, and immunofluorescence to examine NCC expression and in vivo measurement of urinary K+ excretion to determine baseline renal-EK in mice treated with an mTORc2 inhibitor and in DCT-specific rapamycin-insensitive companion of mTOR knockout (DCT-RICTOR-KO) mice.

Results
Inhibition of mTORc2 with AZD8055 abolished high-K+–induced inhibition of Kir4.1/Kir5.1 in DCT, high potassium–induced depolarization of the DCT membrane, and high potassium–induced suppression of phosphorylated Na-Cl cotransporter (pNCC) expression. AZD8055 stimulated the 40-pS inwardly rectifying K+ channel (Kir4.1/Kir5.1-heterotetramer) in early DCT in the mice on overnight high potassium intake; this effect was absent in the presence of protein kinase C inhibitors, which also stimulated Kir4.1/Kir5.1. AZD8055 treatment decreased renal-EK in animals on overnight high-potassium diet. Deletion of RICTOR in the DCT increased the Kir4.1/Kir5.1-mediated K+ currents, hyperpolarized the DCT membrane, and increased the expression of pWNK4 and pNCC. Renal-EK was lower and plasma K+ was higher in DCT-RICTOR-KO mice than corresponding control mice. In addition, overnight high-potassium diet did not inhibit Kir4.1/Kir5.1 activity in the DCT and failed to inhibit the expression of pNCC in DCT-RICTOR-KO mice. Overnight high potassium intake stimulated renal-EK in control mice, but this effect was attenuated in DCT-RICTOR-KO mice. Thus, overnight high potassium intake induced hyperkalemia in DCT-RICTOR-KO mice but not in control mice.

Conclusions
mTORc2 of the DCT inhibits Kir4.1/Kir5.1 activity and NCC expression and stimulates renal-EK during high potassium intake.
Investigating the Relationship between Religiosity and Post-Traumatic Stress Disorder in Mothers of Children with Cancer Admitted to t Pediatric Oncology Department of Shahid Sadoughi Hospital , Yazd , 2019
Authors: Pourmovahed Zahra , Mirtezerjani Motahareh Sadat , Ardian Nahid , Akhondzardini Razieh 
Published: May 2024

Introduction: Religiosity can help in adapting to difficult situations and provide better care. Therefore, this study was conducted to determine the relationship between religiosity and post-traumatic stress disorder in mothers of children with cancer.
Methods: This was a cross-sectional and descriptive-correlational study conducted on 115 mothers of children with cancer who were admitted to Shahid Sadoughi Hospital, in Yazd, in 2019. Sampling was done through convenience sampling method. Data collection tools were the demographic information questionnaire, and Mississippi PTSD and Glock and Stark questionnaires. . Descriptive (mean and standard deviation) and analytical (Pearson's correlation, chi-square) statistical tests and indicators were used; data were investigated and statistically analyzed using SPSS 21 software with a confidence level of 95%.
Results: The findings showed that in the post-traumatic stress disorder questionnaire, the average score was 97/61±36/78 and the average score of the religiosity questionnaire was 26/77±61/85. Pearson's correlation coefficient showed a negative relationship between religiosity and PTSD (p= 0/160, r= -0/132). The average score of PTSD and religiosity among mothers was not significantly different according to various variables such as mother's occupation, child's gender, and education level. The difference in the average score of PTSD in mothers was different according to the characteristics such as education level and occupation. The average score of religiosity was more different when comparing working mothers with housewives. The average stress score after the accident showed a greater difference in mothers according to the type of child's illness. The average PTSD score was 83/87±25/79 for neuroblastoma and 92/33±24/98 for solid tumor disease.
Conclusion: PTSD among mothers was close to the cut-off point for the disorder. Although there was no significant relationship between PTSD and mothers' religiosity, it can be said that the severity of mental situation of mothers with severe cancer was effective in the study.
SUBJETIVIDAD EN LA NARRACIÓN: EL IMPERFECTO EN EL ESPAÑOL PERUANO AMAZÓNICO
Authors: Jara Yupanqui Ileana Margarita 
Published: May 2024

Este artículo analiza los usos del Imperfecto del indicativo en el español peruano amazónico, una variedad formada en situación de intenso contacto lingüístico. Típicamente el Imperfecto porta valor durativo por oposición al sentido puntual del pretérito, valor continuo en contraste al carácter delimitativo del segundo y valor indefinido en referencia a una situación pasada no específica, a diferencia del Pretérito que alude a la totalidad del evento (García Fernández, 2008; Cipria y Roberts, 2001, p. 300). Usando como marco de referencia los enfoques teóricos temporal, aspectuales, y con énfasis en el contexto y el discurso (Rojo, 1990, 1999; García Fernández, 2008; Hopper y Thompson 1980, p. 251; Fleischman, 1990, p.168), se examinan usos prototípicos y atípicos del Imperfecto. Estos últimos consisten en poner los eventos en primer plano, una función usualmente desempeñada por el Pretérito. El examen de los datos muestra que los valores del Imperfecto están constreñidos por el aspecto léxico del verbo, los modificadores adverbiales temporales, el tipo de estructura narrativa en el que aparecen (Labov y Waletzky, 1997[1967], p. 3). Estos son empleados con propósitos pragmáticos que manifiestan la subjetividad del narrador. Los datos consisten en narraciones de experiencias personales a hablantes monolingües recogidas a través de entrevistas sociolingüísticas conducidas en la ciudad de Iquitos, Perú.
SOBRE METÁFORA E LINGUAGEM: A ESTILÍSTICA DA RETÓRICA CLÁSSICA CICERONIANA EM PERSPECTIVA
Authors: Jesus Carlos Renato Rosário de 
Published: May 2024

Este trabalho constitui parte de nossas pesquisas sobre a prosa rítmica na Antiguidade clássica e lida com os recursos retóricos propostos e utilizados por Cícero no discurso oratório, conforme tratado pelo orador romano na sua obra Orator. Para este momento, estabelecemos um recorte em que seja possível verificar o papel das figuras (gr. ???????, schémata) – com ênfase na metáfora – na organização da elocutio, incluindo aí a importância e a relação da metáfora na linguagem poética, passando pela sua percepção rítmica, exemplificada em sua ligação com a música, até a discussão acerca de sua relevância no eixo mais complexo da linguagem enquanto sistema de signos. Esperamos deixar evidente que os usos da metáfora no discurso oratório movimentam as emoções do auditório, pois o sentido que lhes é atribuído, tanto da parte do orador, quanto da parte do auditório, funciona como um mecanismo cognitivo, envolto no sistema linguístico da própria língua, a qual, por sua vez, favorece tais usos, interligando-os às diversas formas de expressividade artística (poesia, música), além de possibilitar-lhes o gerenciamento dos (pluri)significados que lhes são disponíveis.
DOS PÉS COMO DILDO: UMA ANÁLISE CONTRASSEXUAL DA POESIA DE GLAUCO MATTOSO
Authors: CERDEIRA JOÃO PEDRO 
Published: May 2024

Este artigo tem como objetivo discutir os aspectos queer no interior da poesia do escritor brasileiro Glauco Mattoso, a partir de elementos como a violência e da podolatria - amplamente presentes no trabalho do autor. Para tal empreitada, nos valeremos principalmente dos conceitos de “contrassexualidade” e “dildo” cunhados pelo filósofo Paul Beatriz Preciado em seu Manifesto Contrassexual (2014) como chaves de leitura para a obra de Mattoso.