bluuebunny/crossref_metadata_2025_split huggingface dataset:
Satisfaction strength and intention to purchase a new product
Authors: Tudoran Ana Alina , Olsen Svein Ottar , Dopico Domingo C. 
Published: May 2012

ABSTRACTThis study examines the role of satisfaction strength on the correspondence between reported satisfaction and intention to purchase a new product. The market testing underlying this study analyzes the market opportunities for a novel prototype. The research was conducted at a central location with 239 randomly selected consumers. Results indicate that (un)certainty, ambivalence, and importance cognitions and feelings significantly moderate the relationship between reported satisfaction and individuals' intention to purchase. For example, the association between consumers' reported satisfaction level and purchasing intention of the new product is weaker as uncertainty increases. Significant moderated‐mediation and mediated‐moderation effects were also found with Structural Equation Modelling. Judgments of ambivalence moderate the satisfaction–purchasing intention relationship through the mediating effect of importance. (Un)certainty fully mediates the moderating effect of importance on the satisfaction–purchasing intention link. The research validates the usefulness of assessing the satisfaction strength concept and illustrates its potential as a better predictor of intentions than satisfaction level alone. The study argues on the nomological validity of the satisfaction construct and reveals that assessment of satisfaction strength should support the management goal of identifying truly satisfied customers. Copyright © 2012 John Wiley & Sons, Ltd.
Does an iPod make you happy? An exploration of the effects of iPod ownership on life satisfaction
Authors: Cockrill Antje 
Published: May 2012

ABSTRACTThe Apple iPod is currently the undisputed leading product in the global MP3 player market. This competitive advantage is due to the design, high functionality, and perhaps most importantly, the ‘cool factor’ which Apple has managed to obtain with its products. This study explores if owning an iPod (as opposed to another brand of MP3 player) makes a difference in the perception of general life satisfaction. Using Diener et al.'s generic satisfaction with life scale (SWLS) to measure the dependent variable life satisfaction, a model with the key concepts usage, benefits, peer influence, design, iPod phenomenon, and iPod bubble has been developed and tested in a variety of ways, including regression analysis. The sample consisted of a multinational sample of 240+ young adults, aged 18–35 years. The demographic profiles of iPod and non‐iPod owners were very similar, but for iPod owners, 23 per cent of the variance in overall life satisfaction is explained by the key concepts used in this research. Key influencing variables for iPod owners are peer influence and design. For non‐iPod owners, the amount of variance explained by the independent variables was negligible. iPod owners also considered their MP3 players to be much ‘cooler’ than did non‐iPod owners. This article considers the managerial implications of these findings for Apple and for competing brands. The social implications of these findings and their significance are also discussed, and several potential areas for further research are highlighted. Copyright © 2012 John Wiley & Sons, Ltd.
Plasmonic Trapping with a Gold Nanopillar
Authors: Wang Kai , Crozier Kenneth B. 
Published: May 2012

AbstractAn improved ability to manipulate nanoscale objects could spur the field of nanotechnology. Optical tweezers offer the compelling advantage that manipulation is performed in a non‐invasive manner. However, traditional optical tweezers based on laser beams focused with microscope lenses face limitations due to the diffraction limit, which states that conventional lenses can focus light to spots no smaller than roughly half the wavelength. This has motivated recent work on optical trapping based on the sub‐wavelength field distributions of surface plasmon nanostructures. This approach offers the benefits of higher precision and resolution, and the possibility of large‐scale parallelization. Herein, we discuss the fundamentals of optical manipulation using surface plasmon resonance structures. We describe two important issues in plasmonic trapping: optical design and thermal management strategies. Finally, we describe a surface plasmon nanostructure, consisting of a gold nanopillar that takes these issues into consideration. It is shown to enable the trapping and rotation (manual and passive) of nanoparticles. Methods by which this concept can be extended are discussed.
Controllable synthesis of well‐aligned CuO nanotube arrays using porous alumina templates
Authors: Zhu Y. F. , Zhou G. H. , Lin Y. B. , Liu L. 
Published: May 2012

AbstractIn order to further enhance the performance of CuO in currently existing applications, well‐aligned CuO nanotube arrays with different diameters were fabricated. During the synthesis process, porous anodic alumina films were fabricated, and then the synthesis of CuO nanotube arrays was realized by using the obtained porous anodic alumina films as templates. The morphology and structure of the obtained products has been confirmed by field‐emission scanning electron microscopy, transmission electron microscopy and X‐ray diffraction measurements. Due to the large surface area of the synthesized products, the prepared CuO nanotube arrays may have potential applications in catalyzing and gas sensing area.
Effect of anisotropic incidence and atomic arrangement of CoFe system magnetic thin films for the gigahertz frequency in the carousel sputtering method
Authors: Imaizumi Ryoichi , Munakata Makoto , Ohkoshi Masatoshi , Maki Kouichirou 
Published: May 2012

AbstractTo increase the uniaxial magnetic anisotropy in thin‐film materials is a key issue for micro‐magnetic devices driven at gigahertz frequencies. It is known that an especially large uniaxial magnetic anisotropy is induced only by the carousel sputtering method. In this paper, the atomic deposition process of CoFeB and CoFe films was analyzed by using a simulation of kinetic theory of gases. The results showed that the sputtered particles had markedly anisotropic incidence on the substrate, leading to different atomic distances with respect to the direction of incidence, resulting in a magnetioelastic effect. These sputtered particles with anisotropic incidence are a main cause of the higher uniaxial magnetic anisotropy of the films. © 2012 Wiley Periodicals, Inc. Electron Comm Jpn, 95(6): 58–65, 2012; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10426
Perylenequinones: Isolation, Synthesis, and Biological Activity
Authors: Mulrooney Carol A. , O'Brien Erin M. , Morgan Barbara J. , Kozlowski Marisa C. 
Published: May 2012

AbstractThe perylenequinones are a class of natural products characterized by a pentacyclic conjugated chromophore giving rise to photoactivity. Potentially useful light‐activated biological activity, targeting protein kinase C (PKC), has been identified for several of the natural products. Recently discovered new members of this compound class, as well as several related phenanthro‐perylenequinones, are reviewed. Natural product modifications that improve biological profiles are outlined, as well as avenues for the total synthesis of analogs not available from the natural product series. An overview of structure/function relationships is provided.
Oxidative Ring Opening of 1,3‐Diarylbenzo[c]heterocycles Using m‐CPBA: Preparation of 1,2‐Diaroylbenzenes
Authors: Nandakumar Meganathan , Sivasakthikumaran Ramakrishnan , Mohanakrishnan Arasambattu K. 
Published: May 2012

AbstractAn unprecedented oxidative cleavage of benzo[c]heterocycles using m‐CPBA is reported. The reaction of 1,3‐diaryl benzo[c]heterocycles with m‐CPBA (meta‐chloroperoxybenzoic acid) at room temperature for 5 min led to the formation of 1,2‐diaroylbenzenes in good to excellent yields.
Several mechanisms lead to the inactivation of the CDKN2A (P16), P14ARF, or CDKN2B (P15) genes in the GCB and ABC molecular DLBCL subtypes
Authors: Guney Suzan , Jardin Fabrice , Bertrand Philippe , Mareschal Sylvain , Parmentier Françoise , Picquenot Jean‐Michel , Tilly Hervé , Bastard Christian 
Published: May 2012

AbstractDiffuse large B‐cell lymphoma (DLBCL) represents the most frequent type of aggressive lymphoma. Deletions of the CDKN2A locus, encoding the proteins CDKN2A (P16), P14ARF, and of the CDKN2B locus, encoding the protein CDKN2B (P15), affect one‐third of DLBCL patients. Although other mechanisms that decrease gene expression have been reported, such as promoter methylation, the prognostic value of these mechanisms is still unclear. We studied the deletion and methylation status of these genes in 171 patients and correlated the genomic results with their mRNA expression level and clinical outcome. CDKN2A, P14ARF, and CDKN2B deletions were significantly correlated with decreased mRNA expression (P < 0.0001, P < 0.0001, and P = 0.0148, respectively). P14ARF was methylated in only two patients (1.3%), whereas CDKN2A and CDKN2B were methylated in 36.7 and 31.4% of patients, respectively. Methylation levels greater than 25% were associated with decreased expression of CDKN2A (P = 0.0169). CDKN2A and CDKN2B inactivation by deletion or methylation was observed in 42.7 and 37.4% of cases, respectively. Including P14ARF deletions, we identified an inactivating mechanism for at least one of these genes in 47% of patients. Although gene inactivation was not correlated with the international prognostic index, P14ARF and CDKN2B inactivation was significantly associated with shorter survival (P = 0.0048 and P = 0.0413, respectively), whereas CDKN2A was not (P = 0.085). Low mRNA expression levels of these genes were correlated with the ABC phenotype. Furthermore, our results show that an inactivating methylation was more frequent in the GCB phenotype. © 2012 Wiley Periodicals, Inc.
Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations
Authors: López Cristina , Delgado Julio , Costa Dolors , Conde Laura , Ghita Gabriela , Villamor Neus , Navarro Alba , Cazorla Maite , Gómez Cándida , Arias Amparo , Muñoz Concha , Baumann Tycho , Rozman María , Aymerich Marta , Colomer Dolors , Cobo Francesc , Campo Elías , López‐Guillermo Armando , Montserrat Emili , Carrió Ana 
Published: May 2012

AbstractChronic lymphocytic leukemia (CLL) is the most common leukemia among adults in Western countries. Chromosomal abnormalities commonly found using conventional cytogenetics and FISH are del(11)(q22‐23), trisomy 12, del(13)(q14), and del(17)(p13). Trisomy 12 is the most frequent numerical abnormality in CLL. It can appear isolated or associated with other chromosomal aberrations, including t(14;18)(q32;q21) and trisomy 18. The aim of this study was to determine whether CLL patients with isolated trisomy 12 or associated with other chromosomal alterations have different clinico‐pathological features, including a different distribution NOTCH1 mutation. Patients were classified into four groups: Group 1, isolated trisomy 12 (n = 14); Group 2, trisomy 12 plus trisomy 18 (n = 4); Group 3, trisomy 12 plus t(14;18) (n = 8); and Group 4: patients with trisomy 12 plus other abnormalities not involving BCL2 (n = 28). The Binet stage and expression of ZAP70 were significantly different among cytogenetic groups. NOTCH1 mutations were detected in 6/12 (50%) patients from Group 1, 4/25 (16%) patients from Group 4, and in no patient from groups 2 and 3 (P = 0.020). Patients in Group 2 had a more rapid disease progression (median Treatment‐free Survival 2 months) as against patients from Groups 1 (50 months), 3 (69 months), or 4 (68 months; P = 0.001). These findings indicate that the distribution of NOTCH1 mutations in CLL with trisomy 12 is heterogeneous and that the presence of additional chromosomal abnormalities such as trisomy 18 could change the prognosis of these patients. © 2012 Wiley Periodicals, Inc.
CIGARETTE QUITLINES, TAXES, AND OTHER TOBACCO CONTROL POLICIES: A STATE‐LEVEL ANALYSIS
Authors: Brown Henry Shelton , Karson Steve 
Published: May 2012

ABSTRACTThis paper estimates monthly quitline calls using panel data at the state level from January 2005 to June 2010. Calls to state quitline numbers (or 1‐800‐QUITNOW) were measured per million adult smokers in each state. The policies considered include excise taxes, workplace and public smoking bans, and a Peter Jennings television‐based program warning of the health risks of smoking. We found that people anticipating increases in prices begin attempting to quit by calling quitlines. Finally, the Peter Jennings media campaign was highly correlated with quitline calls. Copyright © 2012 John Wiley & Sons, Ltd.
Evaluation of data quality at the Gambia national cancer registry
Authors: Shimakawa Yusuke , Bah Ebrima , Wild Christopher P. , Hall Andrew J. 
Published: May 2012

AbstractThe Gambia National Cancer Registry (GNCR) is one of the few nationwide population‐based cancer registries in sub‐Saharan Africa. Most registries in sub‐Saharan Africa are limited to cities; therefore, the GNCR is important in providing estimates of cancer incidence in rural Africa. Our study assesses the quality of its data. The methods proposed by Bray and Parkin, and Parkin and Bray (Eur J Cancer 2009;45:747–64) were applied to the registry data from 1990 to 2009 to assess comparability, validity and completeness. The system used for classification and coding of neoplasms followed international standards. The percentage of cases morphologically verified was 18.1% for men and 33.1% for women, and that of death certificate only cases was 6.6 and 3.6%, respectively. Incidence rates in rural regions were lower than in the urban part of the country, except amongst young male adults. Comparison with other West African registries showed that the incidences of liver and uterine cervical cancer were comparable, but those of prostate and breast in The Gambia were relatively low. The overall completeness was estimated at 50.3% using the capture–recapture method. The GNCR applies international standard practices to data collection and handling, providing valuable data on cancer incidence in sub‐Saharan Africa. However, the data are incomplete in the rural and elderly populations probably because of health care access and use.
Dexamethasone‐incorporated nanofibrous meshes for antiproliferation of smooth muscle cells: Thermally induced drug‐loading strategy
Authors: Son Young Ju , Yoo Hyuk Sang 
Published: May 2012

AbstractPluronic‐immobilized nanofibrous meshes were tailored for thermally induced incorporation of dexamethasone. A diblock copolymer composed of poly(e‐caprolactone)‐poly (ethyleneglycol) (NH2) (PCL‐PEG (NH2)) was electrospun to a nanofibrous mesh, and Pluronic was subsequently surface‐immobilized on the mesh in aqueous phase. Surface‐wettability analysis and 1H NMR spectroscopy confirmed surface‐decoration of nanofibrous meshes with Pluronic moieties depending on the blend ratios of PCL‐PEG(NH2). Fluorescently‐labeled micelles were incorporated in the nanofibrous meshes by temperature modulation and showed attenuated release profiles of the micelles were for 1 month. The suppression degree of drug‐loaded micelle releases was proportional to the blend ratio of PCL‐PEG(NH2). Dexamethasone was formulated into micellar nanoaggregates, and the dexamethasone micelles‐loaded nanofibrous meshes were used for antiproliferation studies of smooth muscle cells. Flow cytometric analysis of the arrested cells at a G0–G1 phase revealed that the dexamethasone micelles‐loaded nanofibrous meshes effectively controlled proliferation of the smooth muscle cells when cells were cultivated with the nanofibrous meshes. The antiproliferation effects of the nanofibrous meshes were closely correlated to the release profiles of the micelles from the nanofibrous meshes with different blend ratios. Thus, dexamethasone‐incorporated nanofibrous meshes can be potentially used for treatments of restenosis after percutaneous transluminal coronary angioplasty. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A 100A:2678–2685, 2012.
Sustained delivery of paclitaxel using thermogelling poly(PEG/PPG/PCL urethane)s for enhanced toxicity against cancer cells
Authors: Loh Xian Jun , Yee Benjamin Jia Han , Chia Fu Siong 
Published: May 2012

AbstractA multiblock poly(ether ester urethane)s comprising poly(ε‐caprolactone), poly(ethylene glycol), and poly(propylene glycol) segments was synthesized. The aqueous copolymer solution exhibited thermogelling behavior at a critical gelation concentration of 3 wt %. The chemical structure and molecular characteristic of the copolymers were studied by gel permeation chromatography, NMR, and fourier transform infrared spectroscopy (FTIR). Rheological characterizations on the thermogel were carried out. Drug release studies using paclitaxel showed that sustained drug release of more than 2 weeks can be achieved with this system. The paclitaxel‐loaded gels showed efficiency in the control of the growth of HeLa cells when compared with the paclitaxel dissolved in solution or paclitaxel encapsulated in Pluronics F127. The results demonstrated that the copolymers could be potentially used in chemotherapeutic applications. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A 100A:2686–2694, 2012.
Titania‐polymeric powder coatings with nano‐topography support enhanced human mesenchymal cell responses
Authors: Mozumder Mohammad Sayem , Zhu Jesse , Perinpanayagam Hiran 
Published: May 2012

AbstractTitanium implant osseointegration is dependent on the cellular response to surface modifications and coatings. Titania‐enriched nanocomposite polymeric resin coatings were prepared through the application of advanced ultrafine powder coating technology. Their surfaces were readily modified to create nano‐rough (<100 nm) surface nano‐topographies that supported human embryonic palatal mesenchymal cell responses. Energy dispersive x‐ray spectroscopy confirmed continuous and homogenous coatings with a similar composition and even distribution of titanium. Scanning electron microscopy (SEM) showed complex micro‐topographies, and atomic force microscopy revealed intricate nanofeatures and surface roughness. Cell counts, mitochondrial enzyme activity reduction of yellow 3‐(4,5‐dimethythiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide (MTT) to dark purple, SEM, and inverted fluorescence microscopy showed a marked increase in cell attachment, spreading, proliferation, and metabolic activity on the nanostructured surfaces. Reverse Transcription‐ Polymerase Chain Reaction (RT‐PCR) analysis showed that type I collagen and Runx2 expression were induced, and Alizarin red staining showed that mineral deposits were abundant in the cell cultures grown on nanosurfaces. This enhancement in human mesenchymal cell attachment, growth, and osteogenesis were attributed to the nanosized surface topographies, roughness, and moderate wetting characteristics of the coatings. Their dimensional similarity to naturally occurring matrix proteins and crystals, coupled with their increased surface area for protein adsorption, may have facilitated the response. Therefore, this application of ultrafine powder coating technology affords highly biocompatible surfaces that can be readily modified to accentuate the cellular response. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A 100A:2695–2709, 2012.
A multinational study to develop universal standardization of whole-body bone density and composition using GE Healthcare Lunar and Hologic DXA systems
Authors: Shepherd John A , Fan Bo , Lu Ying , Wu Xiao P , Wacker Wynn K , Ergun David L , Levine Michael A 
Published: May 2012

Abstract
Dual-energy x-ray absorptiometry (DXA) is used to assess bone mineral density (BMD) and body composition, but measurements vary among instruments from different manufacturers. We sought to develop cross-calibration equations for whole-body bone density and composition derived using GE Healthcare Lunar and Hologic DXA systems.
This multinational study recruited 199 adult and pediatric participants from a site in the US (n = 40, ages 6 through 16 years) and one in China (n = 159, ages 5 through 81 years). The mean age of the participants was 44.2 years. Each participant was scanned on both GE Healthcare Lunar and Hologic Discovery or Delphi DXA systems on the same day (US) or within 1 week (China) and all scans were centrally analyzed by a single technologist using GE Healthcare Lunar Encore version 14.0 and Hologic Apex version 3.0. Paired t-tests were used to test the results differences between the systems. Multiple regression and Deming regressions were used to derive the cross-conversion equations between the GE Healthcare Lunar and Hologic whole-body scans.
Bone and soft tissue measures were highly correlated between the GE Healthcare Lunar and Hologic and systems, with r ranging from 0.96 percent fat [PFAT] to 0.98 (BMC). Significant differences were found between the two systems, with average absolute differences for PFAT, BMC, and BMD of 1.4%, 176.8 g and 0.013 g/cm2, respectively. After cross-calibration, no significant differences remained between GE Healthcare Lunar measured results and the results converted from Hologic.
The equations we derived reduce differences between BMD and body composition as determined by GE Healthcare Lunar and Hologic systems and will facilitate combining study results in clinical or epidemiological studies. © 2012 American Society for Bone and Mineral Research.
Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men
Authors: LeBrasseur Nathan K , Achenbach Sara J , Melton L Joseph , Amin Shreyasee , Khosla Sundeep 
Published: May 2012

Abstract
Skeletal muscle and bone form highly-integrated systems that undergo significant age-related changes, but the relationships between muscle mass and trabecular versus cortical bone or trabecular microarchitecture have not been systematically investigated. Thus, we examined the association between appendicular skeletal muscle mass (ASM) relative to height squared (relative ASM) and bone parameters at several sites assessed by conventional as well as high-resolution peripheral QCT in a cohort of 272 women and 317 men aged 20 to 97 years. In women, relative ASM was associated with cortical thickness (CtTh) at the femoral neck, lumbar spine, radius, and tibia (age-and physical activity adjusted r = 0.19–0.32; all p &lt; 0.01). Relative ASM was also associated with trabecular volumetric bone mineral density (vBMD) at the femoral neck and spine (all p &lt; 0.05), and trabecular bone volume to tissue volume (BV/TV), number (TbN), thickness (TbTh), and separation (TbSp) at the radius (all p ≤ 0.05). In all men, relative ASM was associated with CtTh at all sites (age- and physical activity–adjusted r = 0.17–0.28; all p &lt; 0.01). Associations between relative ASM and trabecular vBMD at the spine in men were lost after adjusting for age; however, relative ASM was associated with trabecular vBMD at the femoral neck and TbN and TbSp at the radius (all p &lt; 0.01). We also investigated circulating factors associated with bone health that may be indicative of relative ASM and found that serum insulin-like growth factor (IGF) binding protein-2 (IGFBP-2) levels were the most robust negative predictors of relative ASM in both sexes. Collectively, these data add to the growing body of evidence supporting the highly-integrated nature of skeletal muscle and bone, and provide new insights into potential biomarkers that reflect the health of the musculoskeletal system. © 2012 American Society for Bone and Mineral Research.