bluuebunny/crossref_metadata_2025_split huggingface dataset:
Informational Coping Style and Depressive Symptoms in Family Decision Makers
Authors: Hickman Ronald L. , Daly Barbara J. , Douglas Sara L. , Clochesy John M. 
Published: September 2010

Background
Overwhelmed family decision makers of chronically critically ill patients must comprehend vital information to make complex treatment decisions that are consistent with patients’ preferences. Exploration of informational coping styles of family decision makers may yield evidence for tailored communication practices supporting the psychological and informational needs of family decision makers.

Objectives
To describe patterns in the demographic characteristics and informational coping styles of family decision makers; to assess differences in informational satisfaction, role stress, and depressive symptoms between family decision makers classified as monitors and as blunters; and to describe the predictive associations between informational coping styles, informational satisfaction, and role stress on depressive symptoms in family decision makers.

Methods
A secondary data analysis of 210 family decision makers of cognitively impaired patients who required 3 days or more of mechanical ventilation. On enrollment, decision makers completed the abbreviated Miller Behavioral Style Scale to assess informational coping styles, the Critical Care Family Satisfaction Survey’s informational subscale to assess informational satisfaction, a single-item measure of role stress, and the Center for Epidemiological Studies Depression scale to assess depressive symptoms.

Results
No associations emerged between demographic characteristics and informational coping styles of family decision makers. Monitors had higher depression scores than did blunters. Both information coping style and informational satisfaction influenced depressive symptoms; however, role stress was the most significant predictor.

Conclusions
Family decision makers classified as monitors were at higher risk for depression than were those who seem to avoid information. Targeting monitors with additional psychological and informational support may mitigate their psychological impairment.
Perceived Support Among Families Deciding About Organ Donation for Their Loved Ones: Donor Vs Nondonor Next Of Kin
Authors: Jacoby Liva , Jaccard James 
Published: September 2010

BackgroundFamilies’ experiences in the hospital influence their decisions about donating organs of brain-dead relatives. Meeting families’ support needs during this traumatic time is an obligation and a challenge for critical care staff.Objectives(1) To elicit family members’ accounts of various types of support received and perceived quality of care for themselves and their loved ones when they made the donation decision, and (2) to examine the relationship between these factors and the families’ donation decision.MethodsRetrospective telephone interviews of 199 families from different regions of the country were completed. Aside from demographic data, the survey addressed perceptions of informational, emotional, and instrumental support and quality of care.ResultsOne hundred fifty-four study participants consented to donation; 45 declined. White next of kin were significantly more likely than African Americans to consent. Specific elements of reported support were significantly associated with consent to donate. Donor and nondonor families had differing perceptions of quality care for themselves and their loved ones. Receiving understandable information about organ donation was the strongest predictor of consent.ConclusionsSpecific supportive behaviors by staff as recounted by family members of potential donors were significantly associated with consent to donation. These behaviors lend themselves to creative training and educational programs for staff. Such interventions are essential not only for next of kin of brain-dead patients, but also for staff and ultimately for the public as a whole.
Informal Training in Staff Networks to Support Dissemination of Health Promotion Programs
Authors: Ramanadhan Shoba , Wiecha Jean L. , Gortmaker Steven L. , Emmons Karen M. , Viswanath Kasisomayajula 
Published: September 2010

Purpose. To study informal skill transfer via staff networks as a complement to formal training among afterschool childcare providers implementing a health promotion program. Design. Cross-sectional, sociometric network analysis. Setting. Boston Young Men's Christian Association (YMCA) afterschool programs implementing the iPLAY program. Participants. All 91 staff members at 20 sites were eligible; 80 completed the survey (88% response rate). Measures. At the network level, network density measured system-level connectedness. At the staff level, the independent variable was out degree, the number of individuals to whom respondents noted a program-related connection. The dependent variable was skill gains, the number of key implementation skills gained from the network. Analysis. We mapped the staff program-related social network. We utilized multiple linear regression to estimate the relationship between out degree and skill gains, and we adjusted for clustering of staff in sites. Results. Most staff (77%) reported gaining at least one skill from the network, but only 2% of potential network connections were established. The regression model showed that out degree (i.e., number of program-related contacts) was significantly associated with skill gains (β = .48, p < .01) independent of other variables. Conclusion. Informal skill transfer in staff networks may be a useful complement to formal training for implementation of health promotion programs, but informal skill transfer was likely underutilized in this network. Future research employing longitudinal and/or multisite data should examine these findings in greater detail.
Reliability and Validity of the Youth Asset Survey: An Update
Authors: Oman Roy F. , Vesely Sara K. , Tolma Eleni L. , Aspy Cheryl B. , Marshall LaDonna 
Published: September 2010

Purpose. Improve and expand an existing youth asset scale. Design. Consisted of seven steps: (1) review of poorer-performing items and constructs, (2) literature review for relevant new asset constructs/items, (3) review of revised instrument by panel of experts, (4) qualitative review through focus group research, (5) pilot-test of instrument, (6) evaluation of the performance of the instrument in a longitudinal study, and (7) conduct of test-retest analysis. Subjects/Setting. Youth (N = 1111) recruited through canvassing of randomly selected census tracts and blocks. Measures. Youth Asset Survey (YAS). Analysis. Factor analysis was conducted on 50% of the baseline data and repeated on the second half of the baseline data. Correlations were computed for the test-retest analysis. Results. Following modifications to the YAS based upon qualitative research, the survey was administered to youth (mean age, 14.3years; 53% female; 39% white, 28% Hispanic, 23% African-American, 9% other). Cronbach α = .55–.92. A majority (27 of 34) of α ≥ .65. All items loaded on one construct at α ≥ .40. The final results yielded 17 constructs assessed via 61 items. Spearman correlations and intraclass correlations ranged from .60 to .82 and .58 to .87, respectively. Conclusion. The results generally suggest that the expanded YAS is a reliable and valid measure of assets.
Emotional Health and Weight Gain: A Prospective Study of Midlife Women
Authors: Tucker Larry A. , Earl Ann Bahr 
Published: September 2010

Purpose. Investigate the extent to which risk of weight gain is affected by emotional health. Also, determine the influence of age, baseline weight, physical activity (PA), energy intake, and changes in PA and energy intake on the relationship between emotional health and weight gain. Design. Prospective cohort. Setting. Two metropolitan areas in the Mountain West. Subjects. Total of 256 middle-aged, apparently healthy women. Measures. Emotional health was assessed using the General Well-Being Schedule. PA was measured using Actigraph accelerometers. Energy intake was measured using 7-day weighed food records. All assessments were taken at baseline and again at the follow-up approximately 2 years later. Analysis. Relative risk (RR) was calculated using incidence data. Results. With no variables controlled, women with less than positive (LTP) emotional health had 59% greater risk of weight gain (≥ 2 kg) than women with positive emotional health (RR, 1.59; 95% confidence intervals [CI], 1.04–2.44). After adjustments for each potential confounder individually, risk of weight gain did not change significantly. However, adjusting for all of the potential confounders simultaneously weakened the risk of weight gain (RR, 1.43; 95% CI, .93–2.21). Risk of weight gain (≥ 2 kg) was no greater in depressed women compared with their counterparts. Conclusion. Middle-aged women with LTP emotional health are at significantly increased risk of weight gain over time compared with women with positive emotional health.
Evaluation of Computerized Free Text Sign-Out Notes
Authors: Weinberg S.T. , Lorenzi N.M. , Waitman L.R. , Campion T.R. 
Published: September 2010

Summary
Background: Standardization of sign-out, the transfer of patient information and responsibility between inpatient providers at shift change, is a Joint Commission National Patient Safety Goal intended to improve communication and reduce risk of error. Computerized systems with free text data entry and limited structure allow clinicians to generate sign-out notes in a variety of ways.
Objective: The literature lacks a systematic exploration of the range of content generated by users of computerized sign-out systems. The goal of this study was to determine if and how clinicians record standardized sign-out information using a system with free text data entry and limited structure.
Methods: Using qualitative methods, we reviewed free text sign-out notes for 730 patient cases across 39 hospital units at an academic medical center.
Results: Two categories of information expression emerged from analysis: patient treatment— comprised of patient summaries, awareness items, and action items—and care team coordination— consisting of discharge information, contact information, and social concerns. A third category describing the format of sign-out note content, presentation of information, also emerged. Location and structure of information varied, but sign-out note content for some hospital units exhibited specific characteristics and was relatively standardized.
Conclusion: Findings provide a baseline understanding of computerized free text sign-out note content. Sign-out notes contained a synthesis of data from disparate sources. We recommend formalizing existing unit-specific content standardization and system use patterns to reduce sign-out note variability and improve communication.
Morpho‐functional modifications of human neutrophils induced by aqueous cigarette smoke extract: comparison with chemiluminescence activity
Authors: Zappacosta B. , Martorana G.E. , Papini S. , Gervasoni J. , Iavarone F. , Fasanella S. , Giardina B. , De Sole P. , Persichilli S. 
Published: September 2010

ABSTRACTCigarette smoking plays an important role as a cause of morbidity and mortality in humans, involving respiratory, cardiovascular, digestive and reproductive systems. Tobacco smoke contains a large number of molecules, some of which are proven carcinogens. Although not fully understood, polymorphonuclear leukocytes seem to play a crucial role in the mechanisms by which tobacco smoke compounds are implicated in smoke‐related diseases. In this paper the effects of an aqueous cigarette smoke extract on the expression of adhesion molecules of polymorphonuclear leukocytes together with the changes in the cell morphology have been related to the chemiluminescence activity. The results obtained show that polymorphonuclear leukocytes treated with aqueous cigarette smoke extract are significantly impaired, as suggested by the changes of chemiluminescence activity, of membrane receptors (CD18, CD62), myeloperoxidase expression and of cell morphology. Altogether the present data indicate that treated polymorphonuclear leukocytes are ineffectively activated and therefore unable to phagocytize zymosan particles. Copyright © 2010 John Wiley & Sons, Ltd.
Development of chemiluminescence method for determination of 10‐hydroxycamptothecin based on luminol–[Ag(HIO6)2]5− reaction in alkaline solution
Authors: Sun Hanwen , Chen Peiyun , Shi Shasha , Li Liqing 
Published: September 2010

ABSTRACTA novel chemiluminescence (CL) method was developed for the determination of 10‐hydroxycamptothecin(HCPT) based on the CL reaction between [Ag(HIO6)2]5− and luminol in alkaline solution. CL emission of Ag(III) complex–luminol in alkaline medium was very different from that in acidic medium. A possible mechanism of enhanced CL emission was suggested. The enhanced effect of HCPT on CL emission of the [Ag(HIO6)2]5−–luminol system was found. The enhanced degree of CL emission was proportional to HCPT concentration. The effect of the reaction conditions on CL emission was examined. Under optimal conditions, the limit of detection was 6.5 × 10−9 g mL−1. The proposed method was applied for the determination of HCPT in real samples with the recoveries of 93.2–109% with the RSD of 1.7–3.3%. Copyright © 2010 John Wiley & Sons, Ltd.
Capillary electrophoresis analysis of isoniazid using luminol‐periodate potassium chemiluminescence system
Authors: Liu Ying , Fu Zhifeng , Wang Lin 
Published: September 2010

ABSTRACTA rapid and simple capillary electrophoresis method coupled with chemiluminescent (CL) detection was proposed for analysis of isoniazid (ISO) based on the enhancement effect of ISO to CL emission of luminol‐periodate potassium reaction. Under the optimal conditions, ISO can be assayed in the range of 7.0 × 10−7 to 3.0 × 10−5 g mL−1 (R2 = 0.9990) with a limit of detection of 3.0 × 10−7 g mL−1 (signal‐to‐noise ratio of 3). The whole analysis process can be completed within 2.5 min with a theoretical plate number of 6258. The relative standard deviations of the signal intensity and the migration time were 3.1 and 1.4% for a standard sample at 1.0 × 10−5 g mL−1 (n = 5), respectively. The presented novel strategy was successfully applied to the determination of ISO in commercial pharmaceutical preparations and spiked human serum samples. Copyright © 2010 John Wiley & Sons, Ltd.
Bacillus subtilis pgsE (Formerly ywtC) stimulates poly‐γ‐glutamate production in the presence of zinc
Authors: Yamashiro Daisuke , Yoshioka Megumi , Ashiuchi Makoto 
Published: September 2010

AbstractPoly‐γ‐glutamate (PGA) is a versatile nylon‐like material, and enhanced production of PGA is required for various bio‐industrial applications. In this study, we first examined the effects of available sugars on the production of Bacillus subtilis PGA, and demonstrated the good applicability of pentoses (e.g., D‐xylose). Then, we characterized the pgsE gene of B. subtilis, which encodes a 6.5‐kDa protein of 55 amino acids (PgsE), as a genetic tool for increasing the yield of PGA without changing its structural features (e.g., polymer stereochemistry and molecular size distribution). In the presence of Zn2+, the induction of PgsE tripled the PGA productivity of B. subtilis subsp. chungkookjang. This finding will contribute to the establishment of an improved PGA‐production system. Biotechnol. Bioeng. 2011; 108:226–230. © 2010 Wiley Periodicals, Inc.
Modulation of viability of live cells by focused ion‐beam exposure
Authors: Shinada Takahiro , Akimoto Takayuki , Zhu Yanwei , Goke Hisa , Ohdomari Iwao 
Published: September 2010

AbstractIntroduction of membrane‐impermeant substances into living cells is the key method to understand contemporary cellular processes by investigating cellular responses and phenotypes. Here, we performed gold ion beam exposure into live cells by using the focused ion beam implantation method, which was originally developed to precisely control semiconductor device performances. We evaluated the viability of the gold‐irradiated cells by measuring the concentration of adenosine triphosphate (ATP), which is an intracellular energy source produced in the mitochondrial membrane. The viability of the irradiated cells was found to be 20% higher than that of the unirradiated control cells. The atoms might promote the energy generating processes within the mitochondrion. Our results suggest that the viability of living cells can be modulated by accurately controlling the dopant atom numbers. Our technique may be considered as a potential tool in life and medical sciences to quantitatively elucidate the dose‐dependent effects of dopants. Biotechnol. Bioeng. 2011; 108:222–225. © 2010 Wiley Periodicals, Inc.
Increasing cellulose accessibility is more important than removing lignin: A comparison of cellulose solvent‐based lignocellulose fractionation and soaking in aqueous ammonia
Authors: Rollin Joseph A. , Zhu Zhiguang , Sathitsuksanoh Noppadon , Zhang Y.‐H. Percival 
Published: September 2010

AbstractWhile many pretreatments attempt to improve the enzymatic digestibility of biomass by removing lignin, this study shows that improving the surface area accessible to cellulase is a more important factor for achieving a high sugar yield. Here we compared the pretreatment of switchgrass by two methods, cellulose solvent‐ and organic solvent‐based lignocellulose fractionation (COSLIF) and soaking in aqueous ammonia (SAA). Following pretreatment, enzymatic hydrolysis was conducted at two cellulase loadings, 15 filter paper units (FPU)/g glucan and 3 FPU/g glucan, with and without BSA blocking of lignin absorption sites. The hydrolysis results showed that the lignin remaining after SAA had a significant negative effect on cellulase performance, despite the high level of delignification achieved with this pretreatment. No negative effect due to lignin was detected for COSLIF‐treated substrate. SEM micrographs, XRD crystallinity measurements, and cellulose accessibility to cellulase (CAC) determinations confirmed that COSLIF fully disrupted the cell wall structure, resulting in a 16‐fold increase in CAC, while SAA caused a 1.4‐fold CAC increase. A surface plot relating the lignin removal, CAC, and digestibility of numerous samples (both pure cellulosic substrates and lignocellulosic materials pretreated by several methods) was also developed to better understand the relative impacts of delignification and CAC on glucan digestibility. Biotechnol. Bioeng. 2011; 108:22–30. © 2010 Wiley Periodicals, Inc.
Intraoperative assessment of sentinel lymph nodes in breast cancer
Authors: Layfield D M , Agrawal A , Roche H , Cutress R I 
Published: September 2010

Abstract

Background
Sentinel lymph node biopsy (SLNB) reduces the morbidity of axillary clearance and is the standard of care for patients with clinically node-negative breast cancer. The ability to analyse the sentinel node during surgery enables a decision to be made whether to proceed to full axillary clearance during primary surgery, thus avoiding a second procedure in node-positive patients.

Methods
Current evidence for intraoperative sentinel node analysis following SLNB in breast cancer was reviewed and evaluated, based on articles obtained from a MEDLINE search using the terms ‘sentinel node’, ‘intra-operative’ and ‘breast cancer’.

Results and conclusion
Current methods for evaluating the sentinel node during surgery include cytological and histological techniques. Newer quantitative molecular assays have been the subject of much recent clinical research. Pathological techniques of intraoperative SLNB analysis such as touch imprint cytology and frozen section have a high specificity, but a lower and more variably reported sensitivity. Molecular techniques are potentially able to sample a greater proportion of the sentinel node, and could have higher sensitivity.
HPLC method development and validation of cytotoxic agent phenyl‐heptatriyne in Bidens pilosa with ultrasonic‐assisted cloud point extraction and preconcentration
Authors: Trivedi Priyanka , Kumar Jonnala Kotesh , Negi Arvind Singh , Shanker Karuna 
Published: September 2010

AbstractExtraction and pre‐concentration of a bioactive marker compound, phenyl‐1,3,5‐heptatriyne from Bidens pilosa, prior to HPLC has been demonstrated using both organic and ecofriendly solvents. Non‐ionic surfactants, viz. Triton X‐100, Triton X‐114 and Genapol X‐80, were used for extraction. No back‐extraction or liquid chromatographic steps were required to remove the target phytochemical from the surfactant‐rich extractant phase. The optimized cloud point extraction procedure has been shown to be a potentially useful methodology for the preconcentration of the target analyte, with a preconcentration factor of 4–99. Moreover, the method is simple, sensitive, rapid and consumes lesser solvent than traditional methods. An isocratic chromatographic separation and quantitation was accomplished on a C18 column with acetonitrile–acidified aqueous as mobile phase at a flow rate of 1.0 mL/min, UV detection at 254 nm and specificity with photo diode‐array detector (PDA) and MS. Under the optimum experimental conditions recovery was satisfactory (99.18–100.33%) without interference from the surfactant. The method seems to be reliable with intraday precision and interday precision below 2.0%. Good linearity was obtained in the working range from 7.5 to 30 µg/mL with correlation coefficient >0.99. The limits of detection and quantitation were 1.84 and 6.13 µg/mL, respectively. The method was validated following international guidelines and successfully applied for quantitative assays of cytotoxic compound phenyl‐1,3,5‐heptatriyne in Bidens pilosa. Copyright © 2010 John Wiley & Sons, Ltd.
Shedding new light on Hierarchical Principal Component Analysis
Authors: Hanafi Mohamed , Kohler Achim , Qannari El Mostafa 
Published: September 2010

AbstractHierarchical Principal Component Analysis (HPCA) is a multiblock method which is designed to reveal covariant patterns between and within several multivariate datasets. The computation of the parameters of this method, namely block scores, block loadings, global loadings and global scores, is based on an iterative procedure. However, very few properties are known regarding the convergence of this iterative procedure. The paper discloses a monotony property of HPCA and exhibits an optimization criterion for which HPCA algorithm provides a monotonic convergent solution. This makes it possible to shed a new light on this method of analysis by showing new properties and pinpointing its relation to existing methods such as Common Component and Specific Weights Analysis (CCSWA), INDSCAL and PARAFAC Models. Copyright © 2010 John Wiley & Sons, Ltd.
ChemInform Abstract: Synthesis and Antiinflammatory Activity of 2,6‐Bis‐tert‐Butylphenol Derivatives.
Authors: TAIT A. , PARENTI C. , ZANOLI P. , VENERI C. , TRUZZI C. , BRANDOLI C. , BARALDI M. , DI BELLA M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Properties of Organic Liquids that are Relevant to Their Use as Solvating Solvents
Authors: MARCUS Y. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.