bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biomimetic Ca‐P coatings incorporating bisphosphonates produced on starch‐based degradable biomaterials
Authors: Oliveira A. L. , Pedro A. J. , Arroyo C. Saiz , Mano J. F. , Rodriguez G. , Roman J. San , Reis R. L. 
Published: August 2009

AbstractIn this study, sodium clodronate, a well‐known therapeutic agent from the family of bisphosphonates (BPs), is incorporated in a biomimetic calcium phosphate (CaP) coating, previously formed on the surface of a starch‐based biomaterial by a sodium silicate methodology, as a strategy to develop a site‐specific drug delivery system for bone tissue regeneration applications. The effects on the resulting CaP coatings were evaluated in terms of morphology, chemistry, and structure. The dissolution of Ca and P from the coating and the release profiles of sodium clodronate was also assessed. As a preliminary approach, this first study also aimed at evaluating the effects of this BP on the viability of a human osteoblastic cell line since there is still little information available on the interaction between BPs and this type of cells. Sodium clodronate was successfully incorporated, at different doses, in the structure of a biomimetic CaP layer previously formed by a sodium silicate process. This type of BPs had a stimulatory effect on osteoblastic activity, particularly at the specific concentration of 0.32 mg/mL. It is foreseen that these coatings can, for instances, be produced on the surface of degradable polymers and then used for regulating the equilibrium on osteoblastic/osteoclastic activity, leading to a controlled regenerative effect at the interface between the biomaterial and bone. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010
Comparative study of toxic effects of zearalenone and its two major metabolites α‐zearalenol and β‐zearalenol on cultured human Caco‐2 cells
Authors: Abid‐Essefi S. , Bouaziz C. , Golli‐Bennour E. El , Ouanes Z. , Bacha Hassen 
Published: August 2009

AbstractZearalenone (ZEN) is a fusarotoxin converted predominantly into α‐zearalenol (α‐Zol) and β‐zearalenol (β‐Zol) by hepatic hydroxysteroid dehydrogenases. The feeding of naturally contaminated grains with ZEN was associated with hyperestrogenic and adverse effects on humans and animals. There is a lack of information on the attribution of the toxic effects of these toxins. One wonders if these effects are due to theparentmolecule (ZEN) or to its major metabolites (α‐Zol and β‐Zol). Using human Caco‐2 cells, we looked for the molecular mechanisms of toxicity of ZEN, α‐Zol, and β‐Zol. Toxicity effects were studied by MTT viability assay and oxidative stress induction by measuring malondialdehyde (MDA) generation. To check whether the oxidative stress induction was associated to DNA lesions, we looked for DNA fragmentation by means of the Comet and the diphenylamine assays. To specify cell death pathway, we investigated caspase‐3 activation, confirmed by poly(ADP‐ribose) polymerase cleavage and by Bcl‐2 depletion. Our results clearly demonstrated that ZEN as well as its two metabolites presented variable toxic effects. They induced cell death and an increase in MDA generation. These effects were associated to DNA fragmentation as well as caspase‐3 activation. The observed toxic effects seem to be relieved by the metabolism of ZEN into α‐Zol and β‐Zol. © 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol 23:233–243, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20284
Coumarin A/AA induces apoptosis‐like cell death in HeLa cells mediated by the release of apoptosis‐inducing factor
Authors: Álvarez‐Delgado Carolina , Reyes‐Chilpa Ricardo , Estrada‐Muñiz Elizabet , Mendoza‐Rodríguez C. Adriana , Quintero‐Ruiz Angelina , Solano José , Cerbón Marco A. 
Published: August 2009

AbstractIt has been demonstrated that naturally occurring coumarins have strong biological activity against many cancer cell lines. In this study, we assessed the cytotoxicity induced by the naturally isolated coumarin A/AA in different cancer cell lines (HeLa, Calo, SW480, and SW620) and in normal peripheral‐blood mononuclear cells (PBMCs). Cytotoxicity was evaluated using the MTT assay. The results demonstrate that coumarin A/AA was cytotoxic in the four cancer cell lines tested and importantly was significantly less toxic in PBMCs isolated from healthy donors. The most sensitive cancer cell line to coumarin A/AA treatment was Hela. Thus, the programmed cell death (PCD) mechanism induced by this coumarin was further studied in this cell line. DNA fragmentation, histomorphology, cell cycle phases, and subcellular distribution of PCD proteins were assessed. The results demonstrated that DNA fragmentation, but not significant cell cycle disruptions, was part of the PCD activated by coumarin A/AA. Interestingly, it was found that apoptosis‐inducing factor (AIF), a proapoptotic protein of the mitochondrial intermembrane space, was released to the cytoplasm in treated cells as detected by the western blot analysis in subcellular fractions. Nevertheless, the active form of caspase‐3 was not detected. The overall results indicate that coumarin A/AA induces a caspase‐independent apoptotic‐like cell death program in HeLa cells, mediated by the early release of AIF and suggest that this compound may be helpful in clinical oncology. © 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol 23:263–272, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20288
Latin bitrades, dissections of equilateral triangles, and abelian groups
Authors: Drápal Aleš , Hämäläinen Carlo , Kala Vítězslav 
Published: August 2009

AbstractLet T=(T*, T▵) be a spherical latin bitrade. With each a=(a1, a2, a3)∈T* associate a set of linear equations Eq(T, a) of the form b1+b2=b3, where b=(b1, b2, b3) runs through T*\{a}. Assume a1=0=a2 and a3=1. Then Eq(T,a) has in rational numbers a unique solution \documentclass{article}\footskip=0pc\pagestyle{empty}\begin{document} $b_{i}=\bar{b}_{i}$\end{document}.
Suppose that \documentclass{article}\footskip=0pc\pagestyle{empty}\begin{document} $\bar{b}_{i}\not= \bar{c}_{i}$\end{document} for all b, c∈T* such that \documentclass{article}\footskip=0pc\pagestyle{empty}\begin{document} $\bar{b}_{i}\not= \bar{c}_{i}$\end{document} and i∈{1, 2, 3}. We prove that then T▵ can be interpreted as a dissection of an equilateral triangle. We also consider group modifications of latin bitrades and show that the methods for generating the dissections can be used for a proof that T* can be embedded into the operational table of a finite abelian group, for every spherical latin bitrade T. © 2009 Wiley Periodicals, Inc. J Combin Designs 18: 1–24, 2010
Correction to: “Transverse quadruple systems with five holes”
Authors: Keranen Melissa S. , Kreher Donald L. 
Published: August 2009

AbstractWe correct an error found in Keranen, Kreher, J Combin Designs 15 (2007), 315–340. © 2009 Wiley Periodicals, Inc. J Combin Designs 17: 492–495, 2009
Clinical psychology students' perceptions of diversity training: a study of exposure and satisfaction
Authors: Green Debbie , Callands Tamora A. , Radcliffe Alison M. , Luebbe Aaron M. , Klonoff Elizabeth A. 
Published: August 2009

AbstractThis study examined clinical psychology graduate students' definitions of diversity and their perceptions of their exposure to and satisfaction regarding their level of diversity training. Four hundred and ninety‐one students from Counsel of University Directors of Clinical Psychology (CUDCP) member programs completed an online survey. Overall, students perceived that their programs considered diversity narrowly, concentrating primarily on ethnicity, race, and culture to the neglect of sexual orientation, religion, language, and physical disability. Likewise, students expressed greater satisfaction with training regarding ethnicity/race and gender than broader areas of diversity, but rated the importance of addressing all areas of diversity as high. Although this study underscores the limited experience that students perceive they have had with various underrepresented groups, programs appear to have incorporated a variety of diversity training modalities that could be expanded upon to meet the interests of psychology students. © 2009 Wiley Periodicals, Inc. J Clin Psychol 65:1–15, 2009.
Family and community influences on educational outcomes among appalachian youth
Authors: Brown Ryan , Copeland William E. , Costello E. Jane , Erkanli Alaattin , Worthman Carol M. 
Published: August 2009

AbstractRecent research has shown how quantifiable aspects of community context affect a wide range of behaviors and outcomes. Due partially to the historical development of this field, currently published work focuses on urban rather than rural areas. We draw upon data from a longitudinal study of families and health in Appalachia—the Great Smoky Mountains Study (GSMS), and an ethnographically based interview tool—the Life Trajectory Interview for Youth (LTI‐Y), to examine the impact of community and family poverty and educational attainment on educational goals and attainment among rural white youth (n=200). Exposure to family poverty and more educated parents were associated with youths' educational attainment. Meanwhile, both community education levels and parental education were associated with college goal‐setting. These relationships were particularly strong among rural white males. This evidence suggests that more attention should be focused on how rural environments affect the lives and life chances of their inhabitants. © 2009 Wiley Periodicals, Inc.
Translational research in action: implementation of the communities that care prevention system in 12 communities
Authors: Fagan Abigail A. , Hanson Koren , Hawkins J. David , Arthur Michael W. 
Published: August 2009

AbstractTranslational research (Pentz, Jasuja, Rohrbach, Sussman, & Bardo, 2006; Woolf, 2008) is concerned with moving advances in prevention science into everyday practice in communities, yet there are few models for ensuring this transfer of knowledge. Communities That Care (CTC) provides a planned, structured, and data‐driven system that trains community prevention coalitions to select evidence‐based programs and replicate them with strong implementation fidelity. In this article, the authors describe the implementation of the CTC prevention system over a 5‐year period in 12 communities participating in the Community Youth Development Study.The results indicated that the intervention communities enacted, on average, 90% of the core components of the CTC system, and achieved high rates of implementation fidelity when replicating a variety of school, afterschool, and parent training programs. These results held over time; communities successfully launched their prevention coalitions and programs and maintained the quality of their prevention services over 5 years. These results indicate that the CTC system can be used to foster translational research. © 2009 Wiley Periodicals, Inc.
Network structural influences on the adoption of evidence‐based prevention in communities
Authors: Fujimoto Kayo , Valente Thomas W. , Pentz Mary Ann 
Published: August 2009

AbstractThis study examined the impact of key variables in coalition communication networks, centralization and density, on the adoption of evidence‐based substance abuse prevention. Data were drawn from a network survey and a corresponding community leader survey that measured leader attitudes and practices toward substance abuse prevention programs. Two types of coalition networks were measured: advice‐seeking and discussion relations. For each community, we computed network‐level measurements (n=20), and then used multiple linear regression. Results showed that adoption outcomes were associated with a decrease in centralization for the advice network and an increase in centralization for the discussion network, controlling for density. This suggests that community coalitions might consider decreasing their network density in such a manner that distributes power and influence among a broader base of coalition members to seek advice about programs while simultaneously discussing these programs in a more concentrated group to facilitate decisions about which programs to adopt. © 2009 Wiley Periodicals, Inc.
Promoting wellness: integrating community and positive psychology
Authors: Schueller Stephen M. 
Published: August 2009

AbstractMany psychological researchers and practitioners aim to promote the wellness of individuals and communities. Community psychology has a rich theoretical tradition related to building competencies and promoting adaptive functioning. Many of these theories, however, have limited empirical support. Recently, the field of positive psychology has pushed for research investigating three areas related to optimal psychological functioning: positive emotions, positive character traits, and positive institutions. Although this call for research has advanced the study of individual well‐being, positive psychology researchers have largely ignored positive institutions. This article aims to tie together the themes and theories of community psychology and positive psychology and highlight how a synthesis of the fields can help better promote community wellness. © 2009 Wiley Periodicals, Inc.
Escaping homelessness: anticipated and perceived facilitators
Authors: Patterson Allisha , Tweed Roger 
Published: August 2009

AbstractOne study with two distinct sections was conducted to identify factors facilitating escape from homelessness. In Section 1, 58 homeless individuals rated possible facilitators of escape (factors they believed would help them become more independent and self‐sufficient). In Section 2, 80 participants who had already exited homelessness rated the same facilitators (factors that would have helped them become more independent and self‐sufficient) and the importance of actual factors that facilitated escape. When rating factors in the hypothetical, both groups rated obtaining housing as being particularly important for facilitating movement toward independence. People formerly homeless who reported perceived facilitators of escape, however, also reported that their escape was facilitated by realization of their own abilities and potential to offer something to the world. The findings have implications for the design of community interventions helping individuals who are homeless. © 2009 Wiley Periodicals, Inc.
Initial evaluation of a cultural approach to implementation of evidence‐based parenting interventions in American Indian communities
Authors: Dionne Renda , Davis Betsy , Sheeber Lisa , Madrigal Luke 
Published: August 2009

AbstractThe current investigation puts forth the authors' conceptualization of a cultural approach to implementing evidence‐based practices with American Indian (AI) families. Their approach involves two phases, the motivational phase, which sets an historical context for current difficulties; and the intervention phase, which links evidence‐based skills with cultural traditions, beliefs, and values. Herein, they present preliminary evidence for the efficacy of the intervention phase, overlaid onto the Incredible Years parenting program (Webster‐Stratton, 1992). Forty‐nine families with American Indian children, ages 3–11 (26 boys), participated in the study; all families participated in the motivational phase and were subsequently randomized to the culturally linked intervention or a control condition. Significant pre‐ and postimprovements in parenting and child behavior were observed in the intervention group. Moreover, a majority of participants reported high levels of satisfaction with the intervention. Results are discussed in relation to approaches to respectful implementation of mainstream, evidence‐based interventions in Indian Country. © 2009 Wiley Periodicals, Inc.
Resilience factors in families living with people with mental illnesses
Authors: Jonker Liezl , Greeff Abraham P. 
Published: August 2009

AbstractIn South Africa, a substantial burden is placed on families living with people with mental illnesses. The aim of this study was to identify resilience factors in families living in an underprivileged area, caring for people with mental illnesses. Data was obtained from family representatives (N=34) using semistructured interviews and a set of seven self‐report, quantitative questionnaires during the course of a once‐off interview. The results of the qualitative analysis show that the most commonly cited resilience factors are religion and spirituality, and personal characteristics of individual family members. Both these factors were cited by 67.6% of the participants. The results of the Spearman correlations showed that the factor that displayed the strongest relationship with family adaptation was the quality of communication in the family unit. © 2009 Wiley Periodicals, Inc.
Community violence exposure and aggression among urban adolescents: testing a cognitive mediator model
Authors: McMahon Susan D. , Felix Erika D. , Halpert Jane A. , Petropoulos Lara A. N. 
Published: August 2009

AbstractPast research has shown that exposure to violence leads to aggressive behavior, but few community‐based studies have examined theoretical models illustrating the mediating social cognitive processes that explain this relation with youth exposed to high rates of violence. This study examines the impact of community violence on behavior through cognitive mediators: normative beliefs about aggression and self‐efficacy to control aggression. Self‐report surveys were completed by two samples (cross‐sectional and longitudinal) of early adolescent, urban African American youth. Structural equation modeling was used to evaluate a theoretical model, and results demonstrated a good fit with both samples; that is more exposure to community violence was associated with more retaliatory beliefs supporting aggression, which led to less self‐efficacy to control aggression, which led to more aggressive behavior. These findings are examined in the context of community factors, and implications for prevention and intervention are discussed. © 2009 Wiley Periodicals, Inc.
Cubic graphs with most automorphisms
Authors: van Opstall Rev. Michael A. , Veliche Răzvan 
Published: August 2009

AbstractWe give a sharp bound for the order of the automorphism group of a connected simple cubic graph on a given number of vertices. For each number of vertices we construct a graph, unique in special cases, attaining the bound. © 2009 Wiley Periodicals, Inc. J Graph Theory 64: 99–115, 2010
Base pairs and pseudo pairs observed in RNA–ligand complexes
Authors: Kondo Jiro , Westhof Eric 
Published: August 2009

AbstractPreviously, a geometric nomenclature was proposed in which RNA base pairs were classified by their interaction edges (Watson–Crick, Hoogsteen or sugar‐edge) and the glycosidic bond orientations relative to the hydrogen bonds formed (cis or trans). Here, base pairs and pseudo pairs observed in RNA–ligand complexes are classified in a similar manner. Twenty‐one basic geometric families are geometrically possible (18 for base pairs formed between a nucleic acid base and a ligand containing heterocycle and 3 families for pseudo pairs). Of those, 16 of them have been observed in X‐ray and/or NMR structures. Copyright © 2009 John Wiley & Sons, Ltd.
A high‐throughput method for controlled hot‐spot fabrication in SERS‐active gold nanoparticle dimer arrays
Authors: Alexander Kristen D. , Hampton Meredith J. , Zhang Shunping , Dhawan Anuj , Xu Hongxing , Lopez Rene 
Published: August 2009

AbstractWe present a high‐throughput method for fabricating large arrays of surface‐enhanced Raman scattering (SERS) active gold dimers. Using a large‐area/low‐cost nanopatterning method in conjunction with a meniscus force deposition technique, we were able to create large arrays of uniformly spaced nanoclusters comprising two 60‐nm gold nanospheres. Raman measurements of a thiophenol monolayer deposited on smaller scale arrays of aligned dimers yielded enhancement factors as high as 109. Polarization‐controlled measurements show spectral peak heights to be 10–100 times smaller when the incident beam is polarized perpendicularly to the dimer axis, confirming that the measured enhancements arise from the ‘hot spots’ between the two nanospheres. Copyright © 2009 John Wiley & Sons, Ltd.
Surface‐enhanced Raman scattering and density functional theory studies of bis(4‐aminophenyl)sulfone
Authors: Diaz‐Fleming Guillermo , Célis Freddy , Fredes Carlos , Campos‐Vallette Marcelo , Aliaga Alvaro E. , Koch Rainer 
Published: August 2009

AbstractRaman and surface‐enhanced Raman scattering (SERS) spectra of dapsone by using colloidal silver nanoparticles have been recorded. Density functional theory was used for the optimization of ground state geometries and simulation of the vibrational spectrum of this molecule. The SERS spectrum with a large silver cluster as a model metallic surface was simulated for the first time. Taking into account the experimental and calculated Raman as well as the SERS normal modes and the corresponding assignments, along with the modeling of the free dapsone and the one in the presence of the colloidal silver nanoparticles, the importance of the sulfone group on the SERS effect in dapsone was inferred. Copyright © 2009 John Wiley & Sons, Ltd.
The comparison of biosorption of nutritionally significant minerals in single‐ and multi‐mineral systems by the edible microalga Spirulina sp.
Authors: Zieliñska Agnieszka , Chojnacka Katarzyna 
Published: August 2009

AbstractBACKGROUND: This paper deals with the biosorption process as a method of enrichment of natural biomass of the edible microalga Spirulina sp. with microelement metal ions, which is of significance in terms of animal nutrition. The influence of the following process parameters was studied for the biosorption of Cr(III): pH and biomass concentration on kinetics and equilibrium of biosorption. The enrichment process were performed in single‐ and multi‐mineral systems for nutritionally significant minerals such as Cu(II), Mn(II), Co(II), Zn(II) and Cr(III) under the conditions that were determined for Cr(III).RESULTS: The best operational parameters for the process were selected as pH 5 and Cs 1 g L−1. The maximum biosorption capacity 71.2 mg g−1, 18.4 mg g−1, 83.9 mg g−1, 31. 8 mg g−1 and 26.5 mg g−1, were reached for Cu(II), Mn(II), Co(II), Zn(II) and Cr(III), respectively. To cover 100% of animal demand on microelements, 4.91 g of the preparation for laying hens and 9 g for swine of enriched microalgae in the single‐metal system should be added to 1 kg of fodder. In the multi‐metal system the competition between microelements was high enough to make it impossible to reach a suitable ratio between bound metal ions.CONCLUSIONS: Two methods of production of mineral feed additives were proposed: a single‐metal system and a multi‐metal system. Performing the biosorption process in the single‐metal system enabled the preparation of additives with the desired composition. Carrying out biosorption in the multi‐metal system is easier, technologically, but the ratio of bound microelements is difficult to predict. Copyright © 2009 Society of Chemical Industry