bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biotechnological Advances in Enzymatic Hydrolysis and Fermentation for Edible Insects: Functionality, Acceptability, and Safety
Authors: Mittal Ravi K. , Krishna Gaurav , Sharma Vikram 
Published: June 2024

Objective:
This review paper examines biotechnological methods for enhancing edible
insects using enzymatic hydrolysis and fermentation. Evaluations involve improving functionality,
analyzing consumer acceptability elements, guaranteeing safety and quality, negotiating
regulatory frameworks, and suggesting field breakthroughs and applications.

Methods:
Our method comprises a thorough literature analysis and academic database searches
for edible insect enzymatic hydrolysis and fermentation investigations. Based on gaps in the
literature, we investigate edible insect safety, consumer acceptability, and legal and regulatory
issues.

Results:
The results show biotechnological advances in enzymatic hydrolysis and fermentation
for edible insect functioning. Sensory and cultural aspects affect consumer acceptability. To
ensure edible insect product safety, hazards and pollutants are addressed. The legal analysis
highlights compliance issues and possibilities.

Conclusion:
This review shows how enzymatic hydrolysis and fermentation improve edible
insect functioning, safety, and nutrition. The review includes consumer acceptability dynamics,
legal issues, and safety analysis.
Preparation and Characterization of PVA Composite Membranes with
TiO2 and TiO2/ZrO2 Nanoparticles: A Comparative Study
Authors: Mehto Akanksha , Chauhan Jyotsna , Mehto Varsha R. 
Published: June 2024

Background::
This study presents the successful fabrication of composite membranes
composed of polyvinyl alcohol (PVA) polymer blended with titanium dioxide (TiO2) nanoparticles
and a combination of titanium dioxide/zirconium dioxide (TiO2/ZrO2) nanoparticles. The features
of composite membranes were analyzed with a specific focus on comparing the characteristics of
PVA/TiO2 and PVA/TiO2/ZrO2 composite membranes.

Methods::
TiO2 and ZrO2 nanoparticles were prepared using the sol-gel method. PVA/TiO2 and
PVA/TiO2/ZrO2 composite membranes were fabricated utilizing the solution casting method. A
controlled method of production of nanoparticles and their uniform dispersion inside the polymer
matrix are the key components contributing to the success of this approach. TiO2 and ZrO2 nanoparticles
and their composite membranes were characterized through various characterization
methods encompassing X-ray diffraction (XRD) study, UV-visible absorption spectroscopy, photoluminescence
(PL) spectroscopy, transmission electron microscopy (TEM), Fourier-transform
infrared (FTIR) spectroscopy and atomic force microscopy (AFM) analysis.

Results::
The XRD study revealed improved crystallinity in composite membranes. The
PVA/TiO2/ZrO2 membrane possessed a greater level of crystallinity than the PVA/TiO2 membrane.
The composite membranes exhibited enhanced absorption and PL behaviour. The FTIR spectra
revealed the creation of a charge-transfer complex among the PVA, TiO2 and ZrO2. The AFM
study indicates that surface roughness increases after doping

Conclusions::
Good concurrence is established between grain size calculated by XRD and TEM.
PVA/TiO2/ZrO2 exhibits more improved characteristics than PVA/TiO2 because of the composite
versatile properties resulting from the combining of two inorganic structural components with polymer.
Such characteristics render it an appealing option for optical and optoelectronic device applications.
Optic Disc Infiltration as a First Sign of Acute Lymphoblastic Leukemia Relapse: A Case Report
Authors: Alamri Saeed S. , Jammah Abdullah A. , AlKhaldi Saleh A. , AlKharashi Abdulkarim A. , Aljatham Adel A. 
Published: June 2024

Introduction
This case report presents a unique manifestation of relapsed B-cell Acute Lymphoblastic Leukemia (ALL) involving the ocular system. This study contributes to the scientific literature by providing documented evidence of ocular complications, specifically central retinal vein occlusion (CRVO), central retinal artery occlusion (CRAO), and optic nerve infiltration, in a patient experiencing the relapse of ALL.

Case Presentation
A 17-year-old male with a history of B-cell ALL presented with decreased vision in the right eye. Clinical examination revealed CRVO, CRAO, and optic nerve infiltration by leukemic cells. Imaging studies confirmed the presence of a retro-orbital mass and subretinal choroidal involvement. Bone marrow aspiration and biopsy confirmed relapsed of ALL. The patient was subsequently referred for further management.

Conclusion
This case highlights the importance of considering ocular manifestations, such as CRVO, CRAO, and optic nerve infiltration, in patients with relapsed ALL. Ophthalmological evaluation should be included in the follow-up and management of ALL patients to detect and manage ocular complications promptly. Early recognition and treatment of ocular manifestations can improve outcomes and quality of life for these patients.
A New Consistent Concept Between the I-change Model and the Transtheoretical Outcome to Imply the Leading Guideline of Depression Behavior Health Change Using Social Media
Authors: Nusawat Piangruthai , Leelasantitham Adisorn 
Published: June 2024

Introduction
The number of patients suffering from depression is growing. It has become a serious global public health issue affecting individuals of all ages, contributing to the primary causes of disabilities and suicides. Therefore, proper care and treatment for patients with depression have become unprecedentedly important.

Objective
The main objective of this study was to present a new, consistent conceptual model for changing the health behavior of patients with depression using social media by combining factors from the I-change model theory with the transtheoretical outcome of behavioral health change and to present guidelines that have implications for practice.

Methods
The research design is quantitative, in which data are collected from a questionnaire according to the proposed conceptual model. One hundred and eighty patients with mild and moderate depression who were aged 18 years and over were recruited using simple random sampling, and the data were analyzed using structural equation modelling.

Results
The results of the study from the perspective of patients with depression found that all elements of the I-change model information, awareness, motivation, intention, and action can explain the consistent relationship between the I-change model factors and the transtheoretical outcome, which represents a related relationship in terms of theory.

Conclusion
Based on the transtheoretical model, the results can be translated into practice for changing health behavior in patients with depression, which may lead to guidelines for designing and implementing treatments targeting behavior modifications in such patients, their caregivers, and other parties involved. Guidelines based on the findings of this study can help reduce the risks of the use of social media in such patients and provide psychiatric knowledge to those involved in the treatment processes. Such guidelines may improve the effectiveness of treatment programs targeting behavior change in patient care.
Respon Pertumbuhan dan Hasil Empat Varietas Bayam Merah (Amaranthus tricolor L.) dengan Pemberian Beberapa Dosis PGPR
Authors: Bellindga Rud Yulika Putri  , Yulianah Izmi 
Published: June 2024

Bayam merah dikenal sebagai sumber makanan yang kaya akan sumber protein, vitamin A, B dan C serta mengandung garam mineral seperti fosfor, kalsium dan zat besi. Pemanfaatan PGPR dan varietas unggul untuk meningkatkan produksi bayam merah. Tujuan dari penelitian ini untuk Mempelajari respon pertumbuhan dan hasil beberapa varietas bayam merah terhadap pemberiaan beberapa dosis PGPR. Penelitian dilaksanakan pada bulan Mei – Juni 2023 di lahan yang bertempat di Desa Duyung, Kecamatan Takeran, Kabupaten Magetan. Bahan yang digunakan adalah benih tanaman bayam merah dengan 4 jenis varietas yaitu varietas Mira, varietas Baret Merah, varietas Red Lady, varietas Manila dan larutan PGPR. Metode penelitian menggunakan Rancangan Acak Kelompok (RAK) yang terdiri dari 2 faktor perlakuan 3 kali ulangan. Data hasil pengamatan dianilisis menggunakan analisi ragam (ANOVA) dan uji lanjut menggunakan BNJ dengan Taraf 5%. Terdapat respon terhadap varietas bayam merah dengan pemberian dosis PGPR (Plant Growth Promoting Rhizobacteria) terhadap pertumbuhan dan hasil tanaman. Respon varietas bayam merah dengan pemberian PGPR terhadap hasil yang didapat tidak berbeda dengan perlakuan tanpa pemberian PGPR (kontrol).

Kata Kunci: Bayam Merah, PGPR, Hasil, Varietas.
Development and Validation of a Measure for Seeking Health Information in the Diabetes Online Community: Mixed Methods Study
Authors: Hughes Allyson S , Beach Sarah , Vasistha Spruhaa , Heydarian Nazanin , Morera Osvaldo 
Published: June 2024

Background
Individuals with chronic diseases often search for health information online. The Diabetes Online Community (DOC) is an active community with members who exchange health information; however, few studies have examined health information brokering in the DOC.

Objective
The aim of this study was to develop and validate the Attitudes Toward Seeking Health Information Online (ATSHIO) scale in a sample of adults with type 1 diabetes (T1D).

Methods
People with T1D were recruited through the DOC, specifically Facebook and Twitter. They were provided with a Qualtrics link to complete the survey. This was a mixed methods study that used thematic analysis along with existing theory and formative research to design the quantitative ATSHIO scale.

Results
A total of 166 people with T1D participated in this study. Confirmatory factor analyses determined a 2-factor scale (Trusting and Evaluating Online Health Information in the DOC and Engaging With Online Health Information in the DOC) with good convergent validity and discriminant validity. Correlations were found between social support, online health information–seeking, diabetes distress, and disease management.

Conclusions
The ATSHIO scale can be used to investigate how people with diabetes are using the internet for obtaining health information, which is especially relevant in the age of telehealth and Health 2.0.
The Willingness of Doctors to Adopt Artificial Intelligence–Driven Clinical Decision Support Systems at Different Hospitals in China: Fuzzy Set Qualitative Comparative Analysis of Survey Data (Preprint)
Authors: Yu Zhongguang , Hu Ning , Zhao Qiuyi , Hu Xiang , Jia Cunbo , Zhang Chunyu , Liu Bing , Li Yanping 
Published: June 2024

BACKGROUND

Artificial intelligence–driven clinical decision support systems (AI-CDSSs) are pivotal tools for doctors to improve diagnostic and treatment processes, as well as improve the efficiency and quality of health care services. However, not all doctors trust artificial intelligence (AI) technology, and many remain skeptical and unwilling to adopt these systems.

OBJECTIVE

This study aimed to explore in depth the factors influencing doctors’ willingness to adopt AI-CDSSs and assess the causal relationships among these factors to gain a better understanding for promoting the clinical application and widespread implementation of these systems.

METHODS

Based on the unified theory of acceptance and use of technology (UTAUT) and the technology-organization-environment (TOE) framework, we have proposed and designed a framework for doctors’ willingness to adopt AI-CDSSs. We conducted a nationwide questionnaire survey in China and performed fuzzy set qualitative comparative analysis to explore the willingness of doctors to adopt AI-CDSSs in different types of medical institutions and assess the factors influencing their willingness.

RESULTS

The survey was administered to doctors working in tertiary hospitals and primary/secondary hospitals across China. We received 450 valid responses out of 578 questionnaires distributed, indicating a robust response rate of 77.9%. Our analysis of the influencing factors and adoption pathways revealed that doctors in tertiary hospitals exhibited 6 distinct pathways for AI-CDSS adoption, which were centered on technology-driven pathways, individual-driven pathways, and technology-individual dual-driven pathways. Doctors in primary/secondary hospitals demonstrated 3 adoption pathways, which were centered on technology-individual and organization-individual dual-driven pathways. There were commonalities in the factors influencing adoption across different medical institutions, such as the positive perception of AI technology’s utility and individual readiness to try new technologies. There were also variations in the influence of facilitating conditions among doctors at different medical institutions, especially primary/secondary hospitals.

CONCLUSIONS

From the perspective of the 6 pathways for doctors at tertiary hospitals and the 3 pathways for doctors at primary/secondary hospitals, performance expectancy and personal innovativeness were 2 indispensable and core conditions in the pathways to achieving favorable willingness to adopt AI-CDSSs.
Revealing hidden biodiversity: Novel insights on Reptile and Amphibian Distribution in Western Ecuador
Authors: Cruz-García Keyko , Zapata-Salvatierra Natalia , Sánchez-Nivicela Juan C. , Chauca Nadia , Matecki Sascha , Perez-Correa Julian 
Published: June 2024

We present notable distributional updates for 13 species from western
Ecuador (six amphibians amphand seven reptiles). Our findings include
the northernmost confirmed sighting of of Pristimantis kuri
(Yánez-Muñoz et al. 2016) and the southernmost documented appearance of
Imantodes inornatus (Boulenger 1896)
and and Lepidoblepharis buchwaldi (Werner 1910). Additionally, we
document new records and notes of distribution range
of of Agalychnis spurrelli (Boulenger
1913), 1913), Hyloscirtus alytolylax (Duellman
1972), 1972), Engystomops montubio (Ron et al.
2004), 2004), Pristimantis nyctophylax (Lynch
1976), 1976), Pristimantis walkeri (Lynch
1974), 1974), Chironius flavopictus (Werner
1909), 1909), Chironius grandisquamis (Peters
1869), 1869), Dendrophidion graciliverpa (Cadle
2012), 2012), Ninia atrata (Hallowell 1845),
and and Urotheca fulviceps (Cope 1886). These observations
significantly contribute to filling information gaps in our
understanding of these species’ distributions. The data, derived from
samples collected across diverse forested areas in the western region of
Ecuador (provinces of Cañar, Guayas, El Oro, and Los Rios), provide
valuable insights into the ecology and conservation of these species.
Hard to face: High rejection sensitivity is associated with preconscious attentional biases to contemptuous facial expressions
Authors: Boland Alexa , Bergmann Summer , Beckes Lane , Harris Joseph 
Published: June 2024

The impact of social rejection varies significantly across individuals,
and can have dire consequences for interpersonal relationships. Previous
research suggests that those higher in rejection sensitivity (RS) show a
hypervigilance to socially-rejecting cues, though results have been
mixed. Participants (n = 36) with Adult Rejection Sensitivity
Questionnaire (A-RSQ) scores in the top (n = 17) and bottom (n = 19)
third of the qualified recruited sample (n = 66) completed two tasks
probing attentional responses to neutral, disgusted, and contemptuous
facial expressions. A novel adaptive staircasing task revealed a greater
attentional bias toward contemptuous faces among high-RS viewers
relative to disgusted and neutral expressions, a pattern not seen among
low-RS viewers. Event-related potential measures revealed distinct
responses to contemptuous faces among high-RS viewers at early stages,
followed by later enhancements to affectively-valenced faces more
generally. Our results show that high-RS viewers process facial
expressions distinctly from those lower in RS and suggest that
contemptuous faces constitute a valid stimulus for isolating social
rejection sensitivity effects.
Patience is Key: The Time It Takes to See Benefits from Continuous Auditing
Authors: Eulerich Marc , Fligge Benjamin , López Kasper Vanessa I. , Wood David A. 
Published: June 2024

SYNOPSIS
Despite research showing numerous benefits of continuous auditing, uptake by internal audit functions has been quite slow. Using a case study approach and field data from a multinational company, we study two possible reasons for the slow uptake of continuous auditing: (1) the time it takes for continuous auditing to result in measurable reductions in audit risks and (2) that not every type of risk is equally likely to improve from continuous auditing. In our case company, it takes three years (on average) before observing significant risk reductions from implementing continuous auditing. We also find that the benefits of implementing continuous auditing vary by risk factor, ranging from no improvement to 51.6 percent for each additional year of continuous auditing use. These findings can provide internal auditors with a realistic expectation of the benefits and limitations, as well as the timetable for realizing benefits, when adopting continuous auditing.
Data Availability: The data used in this study cannot be made publicly available due to confidentiality agreements with the participating organization.
JEL Classifications: M42; G32.
Application of Distilled Liquid Smoke on the Chemical Characteristics of Skipjack Fish Sausage
Authors: Bora Naema , Bunga Senni J. 
Published: June 2024

Smoked sausage is a popular food among people due to its distinctive aroma and taste. Generally, smoked sausages are made using traditional smoking methods. Since the advent of liquid smoke technology, the processing of smoked fish sausages can be done more practically and safely by immersing them in liquid smoke. The aim of this research was to determine the effect of the application of liquid smoke quality and liquid smoke concentration on the chemical characteristics of liquid smoked skipjack tuna sausage. The experiment was executed using a factorial CRD (Completely Randomized Design) with two factors: the quality of liquid smoke, consisting of grade 1, grade 2, and grade 3; and the concentration, consisting of 15%, 25%, and 35% by volume. The results of the study showed that the quality of liquid smoke grades 2, along with a liquid smoke concentration of 25%, can significantly increase the water content, pH, protein content, total acid, and the texture of liquid smoked skipjack tuna fish sausage. Keywords: Chemical characteristics, Fish sausage, Liquid smoke, Distilled liquid smoke.
Breaking The Limitations of Distribution: Creating an Integrated Solution with Saving Matrix and Net Present Value
Authors: Astari Alifah Nur , Fauzi Muchammad 
Published: June 2024

PT BCD is one of the large pharmaceutical companies in Bandung, West Java which plays the role of main distributor. PT BCD is facing a problem related to its company logistics. The problem in question is in the form of customer complaints that reflect a bad image for the company, especially regarding on-time delivery. Many of these complaints came from outlets in the central rayon area consisting of RS A, RS B, RS C, Pharmacy D, Pharmacy E, Pharmacy F, PBF G, PBF H, and PBF I. In an effort to overcome this problem, the management plans to launch a program called same-day delivery service so it is necessary to carry out research that integrates the saving matrix method to determine the most optimal distribution route for pharmaceutical products so that the distance traveled in delivery is the shortest as well as carrying out mathematical considerations regarding fleet investment decisions based on which offers are available. Provides the greatest savings using the total cost of ownership (TCO) net present value method approach. From the results of the analysis of the two integrated methods, a picture of the decision in the form of the most optimal route based on the saving matrix analysis is obtained, namely PT BCD – RS A – RS B – PBF G – PBF H – PBF I – Apotek F – RS C – Apotek E – Apotek D – PT BCD with the decision to procure a fleet in the form of purchasing an L300 type box car. Keywords: Logistic, Net Present Value, Same Day Delivery, Saving Matrix
Peran Religious Coping terhadap Psychological Distress pada Mahasiswa: Scooping Review
Authors: Ayun Qurrotu , Taufik Taufik , Ruhaena Lisnawati 
Published: June 2024

Psychological distress atau tekanan psikologis adalah permasalahan umum yang dialami oleh mahasiswa ditandai dua gejala utama yaitu kecemasan dan depresi. Salah satu cara untuk mengurangi gejala psychological distrees adalah menggunakan religious coping. Tujuan dalam penelitian ini adalah melakukan review studi literatur mengenai peran religious coping terhadap psychological distress. Penelitian ini menggunakan metode scooping review berdasarkan petunjuk PRISMA dan penelusuran artikel melalui tiga database yaitu scopus, sciencedirect serta tandfonline. Pencarian menggunakan kata kunci religious coping, psychological distress serta student college. Artikel dipilih dari publikasi kurun waktu 2012-2023, open access serta berbahasa ingris. Hasil penelitian didapatkan 12 artikel yang relevan mengenai peran religious coping terhadap psychological distresspada mahasiswa. Secara keseluruhan, hasil analisis menyebutkan bahwa religious coping berkorelasi negatif dengan gejala psychological distress. Latar belakang mahasiwa (asal negara, agama, faktor penyebab psychological distress) juga mempengaruhi penggunaan religious coping.
Optimizing BT-1804 Product Quality with Six Sigma Approach
Authors: Apriani Ratna Agil , Basuki Demas Emirbuwono , Handayani Dwi , Wibowo Latifah Fitri Nuraida 
Published: June 2024

PT. Bakrie Autoparts produced BT-1804 products for 12 months, and of the 9537 units produced, there were 3572 product defects with various types of defects. Therefore, Six Sigma with DMAIC is used to minimize defect problems. In stages, define used Critical to Quality (CTQ), where 16 types of potential defects were found in the BT-1804 product. At stage Measure, the Pareto diagram measures the highest frequency of defects and the improvements needed. At stageAnalyze used the Fishbone Diagram, where this method focuses on repairing 1 type of defect in BT-1804, which is the type of machining defect that is the dominant defect. At stageImprove, correcting the root of the problem with FMEA (Failure Mode and Effect Analysis), where it was found that inaccurate machine settings had the highest RPN value of 100. So, suggestions were given by providing knowledge in the form of training related to production mechanisms and providing supervision of operator performance during the machine setting process. Keywords: Quality Improvement, Six Sigma, DMAIC; Failure Mode and Effect Analysis