bluuebunny/crossref_metadata_2025_split huggingface dataset:
High plasma D-dimer levels correlate with ictal infarction and poor outcomes in spontaneous subarachnoid hemorrhage
Authors: Kobata Hitoshi , Sugie Akira , Tucker Adam , Sarapuddin Gemmalynn , Kimura Hitomi , Takeshita Hitoshi , Morihara Munenori , Kawakami Makiko 
Published: May 2024

Structured AbstractBACKGROUNDEarly brain injury (EBI) is the leading cause of poor outcomes in patients with spontaneous subarachnoid hemorrhage (sSAH). Plasma D-dimer levels and acute cerebral ischemia have been highlighted as relevant findings in EBI; however, their correlation has not been substantially investigated.METHODSThis retrospective, single-center cohort study was conducted at a tertiary emergency medical center from January 2004 to June 2022. Consecutive patients with sSAH who presented within 12 h of SAH ictus and underwent magnetic resonance imaging within 3 days were included. We assessed the correlation of plasma D-dimer levels with acute ischemic lesions detected on the diffusion-weighted images (DWI) and the clinical characteristics of patients.RESULTSAmong 402 eligible patients (mean age, 63.5 years; 62.7% women; median time from onset to arrival, 45.5 min), 140 (34.8%) had acute ischemic lesions. Higher plasma D-dimer levels linearly correlated with worse neurological grades, more severe SAH on initial CT, acute ischemic lesions, and poor outcomes, except for patients with neurogenic stunned myocardium. In the multivariate analysis, acute ischemic lesions were significantly associated with worse neurological grades, higher plasma D-dimer levels, bilateral loss of light reaction, and advanced age. The receiver operating characteristic curve analysis showed D-dimer levels as excellent predictors for acute ischemic lesions (area under the curve [AUC], 0.897; cut-off value, 5.7 µg/mL; p <0.0001) and unfavorable outcomes (AUC, 0.786; cut-off value, 4.0 µg/mL; p <0.0001).CONCLUSIONSHigh plasma D-dimer levels correlated with the appearance of acute ischemic lesions on DWI and were dose-dependently associated with worse neurological grades, more severe hemorrhage, and worse outcomes. Plasma D-dimer levels provide a valuable perspective on various issues in the acute phase of sSAH.
Deep Learning Detection of Subtle Torsional Eye Movements: Preliminary Results
Authors: Mukunda Krishna , Ye Tianyi , Luo Yi , Zoitou Asimina , Kwon Kyungmin (Esther) , Singh Richa , Woo JiWon , Sivakumar Nikita , Greenstein Joseph L. , Taylor Casey Overby , Kheradmand Amir , Green Kemar Earl 
Published: May 2024

ABSTRACTThe control of torsional eye position is a key component of ocular motor function. Ocular torsion can be affected by pathologies that involve ocular motor pathways, spanning from the vestibular labyrinth of the inner ears to various regions of the brainstem and cerebellum. Timely and accurate diagnosis enables efficient interventions and management of each case which are crucial for patients with dizziness, vertical double vision, or imbalance. Such detailed evaluation of eye movements may not be possible in all frontline clinical settings, particularly for detecting torsional abnormalities. These abnormalities are often more challenging to identify at the bedside compared to horizontal or vertical eye movements. To address these challenges, we used a dataset of torsional eye movements recorded with video-oculography (VOG) to develop deep learning models for detecting ocular torsion. Our models achieve 0.9308 AUROC and 86.79 % accuracy, leveraging ocular features particularly pertinent to tracking torsional eye position.
Perirhinal and postrhinal cortices are necessary for retrieving latently-acquired stimulus associations
Authors: Peng Xiangyuan , Burwell Rebecca D. 
Published: May 2024

AbstractThe perirhinal and postrhinal cortices reside in the parahippocampal region of the medial temporal lobe. They receive and process sensory information from cortical and subcortical sources and support hippocampal functions via direct connectivity and indirectly via the entorhinal cortex. Previous studies using the sensory preconditioning paradigm have shown that the perirhinal and postrhinal cortices are necessary for associating cues during preconditioning and retrieving the associations during conditioning. However, the question of whether these regions are also required for stimulus association retrieval during re-exposure to the preconditioning cue had not been addressed. Using a chemogenetic approach, we temporarily suppressed the perirhinal or postrhinal cortex in adult male rats during the preconditioning cue test phase. Both suppression groups showed impaired sensory preconditioning compared to sham surgery controls, as indicated by significantly reduced preferential responding. Implications of our findings are discussed in relation to the importance of the PER and POR in context processing and episodic-like memory in animal models.Significance statementAlthough Pavlovian conditioning between two stimuli is widely used in neuroscience, associative learning in the real-world is often too complex to be modeled by first-order conditioning alone. Proper responding may require integrating multiple associations via common elements, i.e. higher-order conditioning, the neural basis of which is not well understood. Whereas existing research indicates the perirhinal and postrhinal cortices in the medial temporal lobe contribute to certain forms of sensory preconditioning (SPC, a type of higher-order conditioning), we suggest their contributions lie in the encoding and retrieving latently acquired associations, processes which are central to all forms of SPC. We argue this interpretation also captures perirhinal and postrhinal contributions to contextual and episodic memory, hence offering a unifying explanation regarding the contributions of these cortices across multiple paradigms.
“Value” emerges from imperfect memory
Authors: Ramírez-Ruiz Jorge , Ebitz R. Becket 
Published: May 2024

AbstractWhereas computational models of value-based decision-making generally assume that past rewards are perfectly remembered, biological brains regularly forget, fail to encode, or misremember past events. Here, we ask how realistic memory retrieval errors would affect decision-making. We build a simple decision-making model that systematically misremembers the timing of past rewards but performs no other value computations. We call these agents “Imperfect Memory Programs” (IMPs) and their single free parameter optimizes the trade-off between the magnitude of error and the complexity of imperfect recall. Surprisingly, we found that IMPs perform better than a simple agent with perfect memory in multiple classic decision-making tasks. IMPs also generated multiple behavioral signatures of value-based decision-making without ever calculating value. These results suggest that mnemonic errors (1) can improve, rather than impair decision-making, and (2) provide a plausible alternative explanation for some behavioral correlates of “value”.
Pregnant women as a sentinel population for genomic surveillance of malaria in the Democratic Republic of Congo
Authors: Onyamboko Marie , Wasakul Varanya , Bakomba Sarah Benie , Kayembe Daddy Kalala , Nzambiwishe Bejos Kifakiou , Ekombolo Pascal Epe , Badjanga Benjamen Basara , Maindombe Jean-Robert Moke , Ngavuka Jephte Ndundu , Lwadi Brunette Nsunda , Drury Eleanor , Ariani Cristina , Goncalves Sonia , Chamsukhee Vanapol , Waithira Naomi , Verschuuren Tess D. , Lee Sue J. , Miotto Olivo , Fanello Caterina 
Published: May 2024

AbstractGenomic surveillance is a valuable tool for detecting changes in the drug susceptibility of malaria parasites, allowing early modification of treatment strategies. However, implementation can be costly and problematic to set up in fragile and high-burden countries, especially when targeting cohorts of children. To address these challenges, we investigated whether in the Democratic Republic of Congo pregnant women attending antenatal care (ANC) services could act as a surrogate sentinel population. Between 2021 and 2023, we conducted a study in Kinshasa, targeting 4,001 pregnant women attending ANCs, and 2,794 children living in the same area. Blood samples from malaria-positive cases were genotyped using an amplicon sequencing platform, to allow comparisons ofPlasmodium falciparumgenomes between the two cohorts and estimations of drug-resistance mutations prevalence. Parasite populations sampled from the two cohorts exhibited highly similar allele frequencies at all tested loci, including drug resistance markers potentially under selection. Pregnant women did not have higher frequencies of sulphadoxine-pyrimethamine resistant haplotypes, which undermine preventive treatments, than children, and we did not find anykelch13mutation at significant frequency. Although parasite densities were lower in adults, the complexity of infection was similar to that in children. There was no evidence ofPlasmodium vivaxinfections in the study. A cohort of pregnant women produces highly similar results to those from children, allowing the implementation of simple and efficient genomic surveillance systems integrated into routine ANC activities, while benefitting women with diagnosis and treatment. ClinicalTrials.gov Identifier:NCT05072613.
Central bank digital currencies: a comprehensive systematic literature review on worldwide research emergence and methods used
Authors: Fahad Shah , Bulut Mehmet 
Published: May 2024

PurposeThe purpose of this paper is to review the literature on Central Bank Digital Currencies (CBDCs) in light of the increasing demand for digital payments globally. It aims to assess the global research landscape, methodologies and data utilized in CBDC studies as their popularity grows.Design/methodology/approachThe paper employs a systematic literature review (SLR) framework, utilizing the Scopus database to identify 323 studies related to Central Bank Digital Currency or CBDC. Through a thorough manual screening process, 169 studies were selected for inclusion. The research employs R, Biblioshiny and Excel for data evaluation, classifying the studies into three methodological categories: quantitative, qualitative and mixed approaches. This classification allows for a detailed assessment of the research techniques and data used in the literature on CBDCs.FindingsThe findings include a diverse range of research methodologies and data employed in CBDCs literature, highlighting the growing interest and depth of academic investigation into this area. By categorizing papers according to research technique, the study provides a comprehensive evaluation of the academic landscape regarding CBDC research. It offers valuable insights for researchers, policymakers and stakeholders, contributing to an enhanced understanding of the complexities and opportunities presented by the development and implementation of CBDCs.Originality/valueThis study’s originality lies in its rigorous and transparent methodology for data from CBDC studies, offering a solid framework for future research. By evaluating global research growth within an SLR framework and categorizing studies by research technique, it contributes uniquely to the academic discourse on digital currencies. The paper provides a critical resource for researchers, lawmakers and stakeholders, enriching the knowledge base on CBDCs and supporting informed decision-making in the context of digital financial innovation.
Impact of innovation, entrepreneurial orientation and entrepreneurial leadership on supply chain resilience in handicraft industry: moderating role of supply chain orientation
Authors: Yadav Uma Shankar , Tripathi Ravindra 
Published: May 2024

PurposeThe study aims to explore dynamic capabilities such as innovation, entrepreneurial leadership, absorptive capability, and the dimension of entrepreneurial orientation in the handicraft sector to enhance supply chain resilience and innovation during unprecedented times. This study also used innovation as a mediating construct and supply chain orientation as a moderating construct.Design/methodology/approachWe gathered data from the handicraft sector in the Uttar Pradesh (UP) in India using a pretested questionnaire. We used variance-based partial least squares structural equation modelling (PLS-SEM) to test our research hypotheses.FindingsOur study indicates that to enhance innovation and improve supply chain resilience, firms should focus on developing dynamic capabilities such as entrepreneurial leadership, absorptive capacity, artificial intelligence (AI), innovativeness, risk-taking ability, and protectiveness. The study highlights the significant role of dynamic capabilities in the handicraft sector during times of crisis, enabling innovation and resilience to risk.Practical implicationsThe study highlights the significant role of dynamic capabilities in the handicraft sector during times of crisis, enabling innovation and resilience to risk.Originality/valueThis study provides significant insights into the current understanding of dynamic capability theory and supply chain orientation and expands upon the existing literature in this field. It comprehensively analyses the latest research and advances knowledge in this area.
Does off-farm work induce farmland abandonment? Evidence from China
Authors: Zheng Linyi 
Published: May 2024

PurposeThis study investigates whether, how and under what circumstances off-farm work induces farmland abandonment, which is of great importance for developing countries to cope with food security.Design/methodology/approachExploiting large-scale panel data from the newly released Chinese Family Database, this study employs a two-way fixed effects model to empirically estimate the causal relationship between off-farm work and farmland abandonment.FindingsIn the context of large-scale labor migration in rural China, current off-farm work leads to an increase in the probability and area of farmland abandoned due to insufficient agricultural labor. However, off-farm work does not harm farm households in plain areas, or villages with land rental markets, abundant agricultural labor, and agricultural machinery, while it harms others. Moreover, farmers who work off-farm in the local area are less likely to abandon their farmland than those in other areas. Additionally, when the number of off-farm workers in a household exceeds two, the probability and area of farmland abandonment will miraculously decline, as the household will no longer live entirely on agriculture.Originality/valueThis study may fill the gap in clarifying the relationship between off-farm work and farmland abandonment, and identify scenarios where off-farm work may not cause farmland abandonment through multiple dimensions, providing insights into the governance of farmland abandonment during rural-urban transformation in developing countries.
Place-based rural development programs and the labor allocation of farm households
Authors: Liu Jhih-Yun , Lee Brian , Chang Hung-Hao 
Published: May 2024

PurposeRural development programs are widely used policy instruments mitigating rural-urban economic disparities. Yet, little research has examined their effect on rural labor. This study fills this knowledge gap by quantifying the causal impact of such programs on the labor allocation of farm households in Taiwan.Design/methodology/approachA theoretical framework based on the agricultural household model is constructed to guide the empirical specification. A unique dataset compiles administrative data on the program’s subsidies with farm household surveys across seven years. To cope with endogeneity bias, an instrumental variables model is applied. The eligibility rule for a township to participate in the program is used as the instrument.FindingsWe find that the program increases the labor supply of farm household members. These effects are more pronounced for off-farm work, particularly non-heads of farm households. The program’s subsidies supporting culture and promotion-related activities have larger effects. Finally, females benefited more from the program.Originality/valueWe focus on farm households since this group is the target of place-based rural development programs. In addition, we identify the causal impact of place-based development programs on rural labor. Finally, this study is relevant to the literature on intra-household models by demonstrating that place-based rural development programs can affect the labor supply of farm household members.
Recommended information adoption by university students in their study/research
Authors: Zha Xianjin , Lu Zeyu , Yan Yalan 
Published: May 2024

Purpose
For undergraduate and graduate students in universities, social media are playing an important role in their study/research because a large amount of academic information has been accumulated on social media. Indeed, social media are complementing university libraries. Given that intelligent recommender systems have been widely implemented on social media, this paper aims to examine the adoption mechanism of intelligently recommended information by university students in their study/research.

Design/methodology/approach
Building upon the updated information system success model and herding theory, this study developed a research model to examine the determinants of recommended information adoption in mobile applications for social media. Data were collected through an online questionnaire and analyzed with partial least squares structural equation modelling.

Findings
The results suggest that herding belief is a valid second-order construct, comprising two first-order dimensions of imitating others and discounting their own information. Information quality, system quality and service quality directly impact satisfaction with the intelligent recommender system. Furthermore, satisfaction with the intelligent recommender system and herding belief directly impact recommended information adoption by university students in their study/research.

Originality/value
This study draws on the updated information system success model and incorporates herding belief as an extended component to investigate recommended information adoption, providing a new lens for understanding recommended information adoption by university students in their study/research.
Glass ceiling in Nigeria’s banking sector: perspectives of senior male employees
Authors: Pepple Dennis Gabriel , Oseghale Raphael , Nmecha Eleanor 
Published: May 2024

Purpose
This study aims to examine senior male employees’ perspectives on the glass ceiling in the Nigerian banking sector.

Design/methodology/approach
The data were collected qualitatively using interviews with 43 senior male employees in four Nigerian banks.

Findings
This study finds that senior male employees acknowledge the challenges their female counterparts face concerning promotion. Senior male employees’ views on the value of gender-diverse leadership underscore the illusion of a “level playing field” because of a gender-neutral performance policy and a family–friendly policy for women. Nonetheless, the study notes a divergence in senior male employees’ perspectives about the professional progression of female employees (based majorly on age and ethnicity). The study concludes that the organisational culture and leadership that underpin poor female career progression are embedded in and driven by the culture in the empirical context.

Originality/value
The examination of senior male employees’ perspectives on the glass ceiling in the Nigerian banking sector offers significant theoretical and practical contributions to the extant literature on gendered occupational segregation by providing unique insights into how patriarchal societal and occupational culture, as well as (limited) family–friendly policies for women, influence the configuration of men’s views of gendered occupational segregation in the Nigerian banking sector.
Gender equity in evaluating higher education faculty competency in Dubai: views from first-year undergraduate students
Authors: Alansaari Hamda , Essary Jessica 
Published: May 2024

PurposeThis study aims to examine the perceptions of male and female Emirati students regarding the competency of male and female faculty members in general introductory courses at a higher education institution in Dubai, which follows a policy of segregating undergraduates by sex.Design/methodology/approachUsing a purposive research design, the study employs focus-group data to investigate the viewpoints of two groups of first-year undergraduates in Dubai (n = 2,43) on the role of gender in shaping their perceptions of faculty competency. Additionally, the researchers utilized open and axial coding schemes to analyze gender perceptions, revealing distinct patterns and thematic outcomes.FindingsThe findings highlight the presence of hidden gender stereotypes that can potentially impact the development of pedagogical relationships in higher education. Based on these findings, the study recommends ways in which students, educators, and administrators may mitigate gender-related bias in faculty evaluations.Originality/valueFurthermore, these insights were designed to contribute to fostering a more equitable educational environment in higher education institutions.
Panarchy theory: myth or reality? Empirical evidence of the socio-ecological nature of supply chains
Authors: Madonna Alice , Boffelli Albachiara , Kalchschmidt Matteo 
Published: May 2024

PurposeThis study builds on the panarchy theory by viewing the supply chain as a socio-ecological system and further expands it by considering the within-level linkages internal to the supply chain level. Three types of linkages are considered: the two cross-level linkages with the planetary and the political-economic levels and the supply chain within-level linkages. The research questions are addressed using the data gathered by the Carbon Disclosure Project within its Supply Chain Programme.Design/methodology/approachThis work aims to study, applying the lens of panarchy theory, how the planetary and the political-economic levels affect the supply chain within-level linkages for sustainability. Furthermore, the difference in how these cross-level linkages influence focal firms and first-tier suppliers is explored.FindingsThe results show that considering the planetary-supply chain linkage, climate change risk exposure is likelier to foster within-level linkages with buyers than with suppliers. Further, climate change mitigation investments have different roles in the different tiers: focal firms are pushed to strengthen the linkages with their suppliers when they lose efficacy in improving their carbon performance, whereas first-tier suppliers exploit investments to gain legitimacy. Discussing the political-economic level effect, perceptions from first-tier suppliers could be two-fold: they could perceive a mandating power mechanism or exploit policymakers’ knowledge to advance their capabilities.Originality/valueThe results contribute to the sustainable supply chain management literature by providing empirical evidence of the cross-level linkages theorised by the panarchy theory. Moreover, the concept of within-level linkages is proposed to apply the theory in this field.