bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wybrane aspekty dostępu do infrastruktury kolejowej i sądowej kontroli rozstrzygnięć w tych sprawach
Authors: Frey Robert , Małecka Elżbieta 
Published: June 2024

Zgodnie z ustawą o transporcie kolejowym Prezes Urzędu Transportu Kolejowego może wydawać decyzje normujące dostęp do infrastruktury kolejowej. Rozwiązanie to stanowi element ochrony przedsiębiorców przed praktykami monopolistycznymi oraz rozwija konkurencję na rynku przewozów kolejowych. Konstrukcja dostępu jest związana z doktryną essentials facilities i została zapoczątkowana w prawie USA.
Celem opracowania jest ukazanie rozwiązań prawnych związanych z dostępem do infrastruktury kolejowej oraz możliwości kontroli sądowej rozstrzygnięć w tych sprawach.
Z analizy przepisów prawa UE, prawa polskiego oraz wydanych przez Prezesa UTK decyzji wynika, że pomimo przyjęcia w prawie polskim rozwiązań wypływających z kolejnych pakietów liberalizacyjnych sektora kolejowego przepisy te tylko częściowo spełniają swoją rolę.
Kemampuan Komunikasi Matematis Siswa pada Materi Penyajian Data di Desa Bojong
Authors: Indriani Hanisah , Noordyana Mega Achdisty 
Published: June 2024

Kemampuan komunikasi matematis akan membuat seseorang bisa menggunakan matematika untuk kepentingan sendiri maupun orang lain sehingga akan meningkatkan sikap positif terhadap matematika. Kemampuan komunikasi matematis siswa pada umumya masih rendah, baik secara lisan maupun tulisan. Rendahnya komunikasi matematis terlihat karena siswa sangat jarang mengemukakan ide-ide matematikanya secara lisan dengan bahasa matematika yang tepat. Tujuan penelitian ini adalah untuk memperoleh deskripsi kemampuan komunikasi matematis siswa MTs kelas VIII pada materi Penyajian Data. Metode penelitian adalah deskriptif kualitatif. Teknik pengumpulan data mencakup observasi, tes, wawancara, instrumen pengumpulan data dan dokumentasi, dengan teknik analisis data menggunakan model analisis Milles dan Huberman. Subjek penelitian adalah lima orang siswa MTs kelas VIII tahun ajaran 2020/2021. Berdasarkan hasil penelitian menunjukkan bahwa subjek penelitian belum menguasai semua indikator kemampuan komunikasi matematis. Hal ini terlihat dari hasil jawaban subjek penelitian yang masih banyak melakukan kesalahan ketika menjawab soal yang diberikan.
Mathematical communication skills will enable someone to use mathematics for their own benefit and for others so that it will increase positive attitudes towards mathematics. In general, students' mathematical communication skills are still low, both orally and in writing. The low level of mathematical communication can be seen because students rarely express their mathematical ideas orally with the right mathematical language. The purpose of this study was to obtain a description of the mathematical communication skills of class VIII MTs students on data presentation material. The research method is descriptive qualitative. Data collection techniques include observation, tests, interviews, data collection instruments and documentation, with data analysis techniques using Milles and Huberman analysis models. The research subjects were five MTs grade VIII students for the 2020/2021 academic year. Based on the results of the study showed that the research subjects had not mastered all indicators of mathematical communication skills. This can be seen from the results of the answers of research subjects who still make many mistakes when answering the questions given.
Assessment of the ecological plasticity of cocksfoot specimens in the Komi Republic
Authors: Tulinov A. G. , Kosolapova T. V. 
Published: June 2024

Relevance. Analyzing the modern requirements of agricultural producers of livestock products for varieties of perennial forage crops, we can identify a number of their main criteria. These are economically valuable traits (high yield, quality indicators, disease resistance), and the length of years spent in grass, and most importantly, high adaptability to the biotic and abiotic environmental factors in which this crop is cultivated.Methods. In the study, which included two stages, an analysis was carried out in a collection nursery of eleven cocksfoot (Dactylis glomerata L.) samples from the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR) (St. Petersburg) of various ecological and geographical origins, geographically related to the northern, arctic region of the Russian Federation (2016–2018) and four numbers of the breeding nursery selected for further testing (2020–2022) according to environmental parameters plasticity, stability and adaptability.Results. Based on the results of research in 2016–2018 of a promising forage cocksfoot crop, it was established that the most valuable breeding material for further hybridization are the varieties Dvina (Russia) and Haka (Finland), which showed a high average yield of two cuttings of green mass – 20.0–20.5 t/ha. Of the cultivars under consideration in 2020–2022, CH-185 (bi – 0.94, σd2 – 0.93) was classified as the most plastic and stable; sample CH-188 (Xsr. – 42.9 t/ha) exceeded the standard Neva (Russia) variety in terms of dry weight yield for two mowing by 2.1 t/ha, and in terms of yield seeds – 40.5 g/m2.
Intensification of the fermentation process of a plant-based drink with complex starter «Bifido Plus»
Authors: Popova N. V. , Kameneva K. S. , Vasiliev A. K. 
Published: June 2024

Relevance. Developing the concept of optimal healthy nutrition increases the demand for the development and production of fortified and functional food products. We propose to use plant-based drinks as a food system for obtaining a probiotic product, which is a source of a number of nutrients. Because the environment in plants isn’t usually good for growing lactic acid bacteria, it’s important to look into different ways to start lactic acid fermentation in these kinds of places.The purpose of these studies is to evaluate ways to intensify the fermentation process of a vegetable drink with a complex starter culture «Bifido plus».Мethods. Research methods include assessment of the increase in microbial biomass, accumulation of lactic acid and exopolysaccharides, and changes in acidity and viscosity of the probiotic drink.Results. The possibility of adaptation of the starter «Bifido Plus» in a plant environment was established, and ultrasonic exposure and the addition of inulin promoted the activation of the fermentation process. In particular, the addition of inulin shortens the lag phase by 0.85 ± 0.05 hours, and exposure to ultrasound treatment increases it by 2.1 ± 0.2 hours. At the same time, the subsequent increase in the volume of biomass accumulation in the sample of the probiotic drink subjected to ultrasound exposure was 60–313% and 28–44% under the influence of inulin. The introduction of inulin and exposure to ultrasound also activate a change in titratable acidity, on average, by 3–15%, the accumulation of lactic acid by 38.7–68%, and the accumulation of exopolysaccharides by 27.3–58.8% relative to the control sample. So, the research results show that ultrasound and inulin can be used to start the fermentation process in plant media. The research was supported by a grant from the Russian Science Foundation (RSF) within the framework of project 23-26-10063.
A Mixed-methods Investigation of the Implications of Cancel Culture for North American Crisis Communications Practitioners
Authors: Brady Anthony 
Published: June 2024

<p>The development of cancel culture theory is imperative for contemporary crisis communications practitioners given the newfound speed and scale of digitally mediated content circulation and elevated frequency of cancellations. Using a mixed-methods approach, this MRP analyzed ten North American corporate cancel culture cases to evaluate the applicability of crisis communication literature to cancel culture and illuminate the stages of a cancelling event. Quantitative hashtag volume data was sourced using Twitter API as scholars have cited Twitter as the preferred platform to initiate a cancelling. Thematic analysis was used to detect themes contained within the sourced corporate communications snippets. A six-stage cycle was conceptualized for an algorithmically induced cancelling on Twitter using polynomial regression analysis. The themes inductively generated through thematic analysis were consistent with crisis communication best practices apart from the antithetical Hold Your Ground theme. </p>
Jet Ice Research Chair in Sustainable Materials Chemistry. TECHNICAL REPORT Y2Q1
Authors: Impellizzeri Stefania , Ortiz Rodriguez Pedro , Hutchins Ryan 
Published: June 2024

<p>The uploaded document is a technical report dated January 10, 2024. The report outlines the research progress and findings and covers two main sections: </p>
<p><br></p>
<p>JI0001: This section discusses the materials research and development efforts for ice paints. </p>
<p><br></p>
<p>JI0002: This part focuses on the quality of water used in ice making. It examines the impact of different types of water contamination and the methods used to purify the water. </p>
Jet Ice Research Chair in Sustainable Materials Chemistry. TECHNICAL REPORT Y2Q2
Authors: Impellizzeri Stefania , Ortiz Rodriguez Pedro , Hutchins Ryan 
Published: June 2024

<p>The uploaded document is a technical report dated April 18, 2024. The report outlines the research progress and findings and covers two main sections: </p>
<p><br></p>
<p>JI0001: This section discusses the materials research and development efforts for ice paints. </p>
<p><br></p>
<p>JI0002: This part focuses on the quality of water used in ice making. It examines the impact of different types of water contamination and the methods used to purify the water. </p>
Hidden Themes in Game: To Enlighten Climate Change Issues Through a Text-based Adventure Game
Authors: Lone Soha 
Published: June 2024

<p>Games have always been there, but sometimes, people may not realize that few might even try to communicate with them about a problem like a climate change that developers might be too afraid to speak publicly because of the fear of a backlash. This paper examines how different game developers incorporate social issues into their storylines and how they can create an impact on the human mind Getting inspiration from a few games like Call of Duty and Horizon Zero Dawn and using the secondary resources, I have developed my own game, Whispers from the Meadows on Figma. This text-based adventure game takes the players through its interactive storyline. It discusses the chaos caused by an organization known as Seductores, which is the primary reason behind the climate change in that Kingdom. Furthermore, it was also observed that graphics, in this case, matters a lot as it was one of the first things that kept the audience engaged throughout the game. Many people mentioned that merging two genres, in this case, text-based and adventure, was captivating. When told about how real-life events inspired the stories, nearly all respondents had no clue of the impact climate change is having on our world or what the experts are telling them for the future if they do not act on climate change quickly. Hence, the goal of this research is to create awareness about this imminent issue in such a way that the players do not feel overwhelmed by it and, instead, by playing this game, feel more motivated and willing to learn more about climate change and how they can battle with it. </p>
Authentok: Uncovering The Authenticity of Lifestyle Tiktoking
Authors: Scarcello Madeline 
Published: June 2024

<p>Alongside the accelerated rise of the popular short-form video app, TikTok has emerged the phenomenon of Lifestyle TikTokers. Lifestyle TikTokers are social media influencers who post daily visual narrations of their seemingly idyllic lives on TikTok. As Lifestyle TikToking grows in popularity, so do the audiences observing these videos. However, unlike other TikTokers with distinctive niches, Lifestyle TikTokers gain their followings by posting aesthetically pleasing and desirable TikToks of what is presumed to be their authentic daily lives. Drawing on previously researched information regarding authenticity and influencer culture, as well as popular Lifestyle TikTok accounts, and conducting first-hand descriptive research, this study reveals that Lifestyle TikToking is not nearly as authentic as it appears to viewers. It argues that multiple factors go into the planning, filming, and editing of these TikToks' which ultimately hinders the validity and authenticity of these posts. </p>
Experimenting With Branching Narratives in Video Form on Streaming Platforms
Authors: Zhang Genyu 
Published: June 2024

<p>With a focus on branching narratives in video form on streaming platforms, or more colloquially, interactive films and series, this research aims to understand how certain formal and creative decisions impact aspects of interactor experiences after the high-profile release of Black Mirror: Bandersnatch. By collecting user tweets and developing a descriptive framework for the subjects' formal traits, it attempts to reveal the connections between them. The 4 selected titles respectively employ a unique set of creative choices and receive varying user response. They not only support how certain creators' choices negotiate the experience, but also reveal the wide variety of contexts in which video-based branching narratives are produced and consumed. From there, the research paints a big picture of the development of live-action interactive titles released between 2019 and 2021. </p>
New Atheism and the Criticism of Islam
Authors: Taira Teemu 
Published: June 2024

One of the ideas in the debates concerning anti-Islamic activities is that atheists, especially prominent celebrity atheists – commonly known as ‘New Atheists’ – have provided support and justification for anti-Islamic attitudes and activities. Given that Sam Harris, one of the so-called New Atheists, stated that he started writing his first book, The End of Faith (2004), immediately after the 9/11 attacks, criticism of Islam is expected to be prevalent among some atheists. The more interesting questions, however, concern what kind of criticism there is, how to make sense of its reasons and motivations, whether it dominates the New Atheist agenda (as some argue), and whether the criticism has been somehow influential in various localities. In examining New Atheist publications and their possible presence at the local level, particularly in Finland, this article suggests that an exceptionally pronounced anti-Islamic approach applies mainly to Harris rather than to New Atheism as a whole. Instead, several other significant aspects come into play, highlighted by other New Atheists, and this is largely true of local atheist activism too. Thus, while a weak link between New Atheists and anti-Islamic activities can be made because of their promotion of strong criticism of religion, New Atheism is not the key to understanding such activities, at least in the Finnish context.
A machine learning model based on clinical features and ultrasound radiomics features for pancreatic tumor classification
Authors: Yao Shunhan , Yao Dunwei , Huang Yuanxiang , Qin Shanyu , Chen Qingfeng 
Published: June 2024

ObjectiveThis study aimed to construct a machine learning model using clinical variables and ultrasound radiomics features for the prediction of the benign or malignant nature of pancreatic tumors.Methods242 pancreatic tumor patients who were hospitalized at the First Affiliated Hospital of Guangxi Medical University between January 2020 and June 2023 were included in this retrospective study. The patients were randomly divided into a training cohort (n=169) and a test cohort (n=73). We collected 28 clinical features from the patients. Concurrently, 306 radiomics features were extracted from the ultrasound images of the patients’ tumors. Initially, a clinical model was constructed using the logistic regression algorithm. Subsequently, radiomics models were built using SVM, random forest, XGBoost, and KNN algorithms. Finally, we combined clinical features with a new feature RAD prob calculated by applying radiomics model to construct a fusion model, and developed a nomogram based on the fusion model.ResultsThe performance of the fusion model surpassed that of both the clinical and radiomics models. In the training cohort, the fusion model achieved an AUC of 0.978 (95% CI: 0.96–0.99) during 5-fold cross-validation and an AUC of 0.925 (95% CI: 0.86–0.98) in the test cohort. Calibration curve and decision curve analyses demonstrated that the nomogram constructed from the fusion model has high accuracy and clinical utility.ConclusionThe fusion model containing clinical and ultrasound radiomics features showed excellent performance in predicting the benign or malignant nature of pancreatic tumors.
Anoikis resistance regulates immune infiltration and drug sensitivity in clear-cell renal cell carcinoma: insights from multi omics, single cell analysis and in vitro experiment
Authors: Wen Xiangyang , Hou Jian , Qi Tiantian , Cheng Xiaobao , Liao Guoqiang , Fang Shaohong , Xiao Song , Qiu Longlong , Wei Wanqing 
Published: June 2024

BackgroundAnoikis is a form of programmed cell death essential for preventing cancer metastasis. In some solid cancer, anoikis resistance can facilitate tumor progression. However, this phenomenon is underexplored in clear-cell renal cell carcinoma (ccRCC).MethodsUsing SVM machine learning, we identified core anoikis-related genes (ARGs) from ccRCC patient transcriptomic data. A LASSO Cox regression model stratified patients into risk groups, informing a prognostic model. GSVA and ssGSEA assessed immune infiltration, and single-cell analysis examined ARG expression across immune cells. Quantitative PCR and immunohistochemistry validated ARG expression differences between immune therapy responders and non-responders in ccRCC.ResultsARGs such as CCND1, CDKN3, PLK1, and BID were key in predicting ccRCC outcomes, linking higher risk with increased Treg infiltration and reduced M1 macrophage presence, indicating an immunosuppressive environment facilitated by anoikis resistance. Single-cell insights showed ARG enrichment in Tregs and dendritic cells, affecting immune checkpoints. Immunohistochemical analysis reveals that ARGs protein expression is markedly elevated in ccRCC tissues responsive to immunotherapy.ConclusionThis study establishes a novel anoikis resistance gene signature that predicts survival and immunotherapy response in ccRCC, suggesting that manipulating the immune environment through these ARGs could improve therapeutic strategies and prognostication in ccRCC.
Development of the CDISC Pediatrics User Guide: a CDISC and conect4children collaboration
Authors: Owen John , Sen Anando , Aurich Beate , Engel Corinna , Cavallaro Giacomo , Degraeuwe Eva , Kalra Dipak , Cornet Ronald , Walsh Melissa , Berkery Teresa , Palmeri Avril , Mahler Fenna , Malik Salma , Persijn Laura , Amadi Chima , Thuet Jacques , Woodworth Simon , Nally Sinead , Leary Rebecca , Marshall Richard , Straub Volker 
Published: June 2024

IntroductionThe conect4children (c4c) project aims to facilitate efficient planning and delivery of paediatric clinical trials. One objective of c4c is data standardization and reuse. Interoperability and reusability of paediatric clinical trial data is challenging due to a lack of standardization. The Clinical Data Interchange Standards Consortium (CDISC) standards that are required or recommended for regulatory submissions in several countries lack paediatric specificity with limited awareness within academic institutions. To address this, c4c and CDISC collaborated to develop the Pediatrics User Guide (PUG) consisting of cross-cutting data items that are routinely collected in paediatric clinical trials, factoring in all paediatric age ranges.Methods and ResultsThe development of the PUG consisted of six stages. During the scoping phase, subtopics (each containing several clinically relevant concepts) were suggested and debated for inclusion in the PUG. Ninety concepts were selected for the modelling phase. Concept maps describing the Research Topic and representation procedure were developed for the 19 concepts that had no (or partial) previous modelling in CDISC. Next, metadata and implementation examples were developed for concepts. This was followed by a CDISC internal review and a public review. For both these review stages, the feedback comments were either implemented or rejected based on budget, timelines, expert review, and scope. The PUG was published on the CDISC website on February 23, 2023.DiscussionThe PUG is a first step in bridging the lack of child specific CDISC standards, particularly within academia. Several academic and industrial partners were involved in the development of the PUG, and c4c has undertaken multiple steps to publicize the PUG within its academic partner organizations – in particular, the European Reference Networks (ERNs) that are developing registries and dictionaries in 24 disease areas. In the long term, continued use of the PUG in paediatric clinical trials will enable the pooling of data from multiple trials, which is particularly important for medical domains with small populations.
Feasibility study of high-power electron linac for clinical X-ray ROAD-FLASH therapy system
Authors: Kutsaev Sergey V. , Agustsson Ronald , Boucher Salime , Carriere Paul , Ghoniem Nasr , Kaneta Kenichi , Kravchenko Maksim , Li Alan , Moro Adam , Patel Sohun , Sheng Ke 
Published: June 2024

Introduction: This study examines how a practical source of X-ray radiation, capable of delivering unprecedented X-ray of 100 Gy/s at 1 m for X-ray FLASH radiotherapy can be designed.Methods: We proposed the design of a linac, capable of accelerating 18 MeV 8 mA electron beam with further conversion to bremsstrahlung X-rays. The design is based on L-band traveling wave accelerating structures with high power efficiency, operating in a short-burst/long-pulse regime that allows operating power supply in a regime, beyond its specifications.Results: This study demonstrates the feasibility of a high-power linac for a clinical X-ray FLASH therapy system, using detailed analysis and simulations. Despite ∼500x higher output than a standard clinical linac, the design utilizes available accelerator components for maximal practicality.Discussion: Recent studies have demonstrated that the FLASH effect that allows to effectively kill tumor cells while sparing normal tissue occurs when large dose rates (≥40 Gy/s) are delivered in less than 1 s. Photons are very attractive since modest energies of several MeV are needed, which can be achieved with compact and cost-efficient accelerators. However, since the efficiency of electron-to-photon conversion is only a few percent, the required beam intensity must be an order of magnitude higher than that state-of-the-art accelerators can provide. The proposed ROAD-FLASH accelerator layout allows achieving both the FLASH dose rate and superior dose conformity, comparing to the similar projects. The current paper focuses on providing a technical roadmap for building an economical and practical linear accelerator for ROAD X-ray FLASH delivery.