bluuebunny/crossref_metadata_2025_split huggingface dataset:
Urinary extracellular vesicle-derived miR-126-3p predicts lymph node invasion in patients with high-risk prostate cancer
Authors: Dong Liang , Hu Cong , Ma Zehua , Huang Yiyao , Shelley Greg , Kuczler Morgan D. , Kim Chi-Ju , Witwer Kenneth W. , Keller Evan T. , Amend Sarah R. , Xue Wei , Pienta Kenneth J. 
Published: June 2024

AbstractTo investigate extracellular vesicles (EVs), biomarkers for predicting lymph node invasion (LNI) in patients with high-risk prostate cancer (HRPCa), plasma, and/or urine samples were prospectively collected from 45 patients with prostate cancer (PCa) and five with benign prostatic hyperplasia (BPH). Small RNA sequencing was performed to identify miRNAs in the EVs. All patients with PCa underwent radical prostatectomy and extended pelvic lymph node dissection. Differentially expressed miRNAs were identified in patients with and without pathologically-verified LNI. The candidate miRNAs were validated in low-risk prostate cancer (LRPCa) and BPH. Four miRNA species (e.g., miR-126-3p) and three miRNA species (e.g., miR-27a-3p) were more abundant in urinary and plasma EVs, respectively, of patients with PCa. None of these miRNA species were shared between urinary and plasma EVs. miR-126-3p was significantly more abundant in patients with HR PCa with LNI than in those without (P = 0.018). miR-126-3p was significantly more abundant in the urinary EVs of patients with HRPCa than in those with LRPCa (P = 0.017) and BPH (P = 0.011). In conclusion, urinary EVs-derived miR-126-3p may serve as a good biomarker for predicting LNI in patients with HRPCa.
“I was always told to fit in, but never to excel”: Men’s Post-Migration Practices of Success in the Public Sector
Authors: Talmi-Cohn Ravit , Chachashvili-Bolotin Svetlana 
Published: June 2024

AbstractWhat post-migration practices of success at the labor market do migrants employ on their way to attaining senior professional positions? This paper offers new insights to the study of migration by focusing on success and masculinity among Ethiopian men, a marginalized group in the Israeli labor market. Using findings from 27 semi-structured interviews and six semi-structured interviews with experts or professionals, we investigate the relationships between career success, gender, and migration through a transnational perspective. Migrant success continues to be assessed and viewed primarily through the lenses of the nation-state and integration, in comparison to the native population in general and in the labor market in particular. This paper analyzes the post-migration practices of success described by migrant men who have achieved senior positions in the public sector, with the aim of illuminating the mechanisms and circumstances, as they understand them, that contribute to achieving success. The findings challenge the concept of integration in the context of migrant men’s success which defines success as fitting in and mediocrity rather than excellence both on the personal and societal level. Although limited to Ethiopian men who have achieved labor market success, this study provides an opportunity to demonstrate the value of examining migrant men’s success from the perspective of cultural capital and views migration masculinity as a dynamic concept.
New liver window width in detecting hepatocellular carcinoma on dynamic contrast-enhanced computed tomography with deep learning reconstruction
Authors: Okimoto Naomasa , Yasaka Koichiro , Cho Shinichi , Koshino Saori , Kanzawa Jun , Asari Yusuke , Fujita Nana , Kubo Takatoshi , Suzuki Yuichi , Abe Osamu 
Published: June 2024

AbstractChanging a window width (WW) alters appearance of noise and contrast of CT images. The aim of this study was to investigate the impact of adjusted WW for deep learning reconstruction (DLR) in detecting hepatocellular carcinomas (HCCs) on CT with DLR. This retrospective study included thirty-five patients who underwent abdominal dynamic contrast-enhanced CT. DLR was used to reconstruct arterial, portal, and delayed phase images. The investigation of the optimal WW involved two blinded readers. Then, five other blinded readers independently read the image sets for detection of HCCs and evaluation of image quality with optimal or conventional liver WW. The optimal WW for detection of HCC was 119 (rounded to 120 in the subsequent analyses) Hounsfield unit (HU), which was the average of adjusted WW in the arterial, portal, and delayed phases. The average figures of merit for the readers for the jackknife alternative free-response receiver operating characteristic analysis to detect HCC were 0.809 (reader 1/2/3/4/5, 0.765/0.798/0.892/0.764/0.827) in the optimal WW (120 HU) and 0.765 (reader 1/2/3/4/5, 0.707/0.769/0.838/0.720/0.791) in the conventional WW (150 HU), and statistically significant difference was observed between them (p < 0.001). Image quality in the optimal WW was superior to those in the conventional WW, and significant difference was seen for some readers (p < 0.041). The optimal WW for detection of HCC was narrower than conventional WW on dynamic contrast-enhanced CT with DLR. Compared with the conventional liver WW, optimal liver WW significantly improved detection performance of HCC.
A Taxonomy of Explanation Types and Need Indicators in Human–Agent Collaborations
Authors: Wachowiak Lennart , Coles Andrew , Canal Gerard , Celiktutan Oya 
Published: June 2024

AbstractIn recent years, explanations have become a pressing matter in AI research. This development was caused by the increased use of black-box models and a realization of the importance of trustworthy AI. In particular, explanations are necessary for human–agent interactions to ensure that the user can trust the agent and that collaborations are effective. Human–agent interactions are complex social scenarios involving a user, an autonomous agent, and an environment or task with its own distinct properties. Thus, such interactions require a wide variety of explanations, which are not covered by the methods of a single AI discipline, such as computer vision or natural language processing. In this paper, we map out what types of explanations are important for human–agent interactions, surveying the field via a scoping review. In addition to the typical introspective explanation tackled by explainability researchers, we look at assistive explanations, aiming to support the user with their task. Secondly, we survey what causes the need for an explanation in the first place. We identify a variety of human–agent interaction-specific causes and categorize them by whether they are centered on the agent’s behavior, the user’s mental state, or an external entity. Our overview aims to guide robotics practitioners in designing agents with more comprehensive explanation-related capacities, considering different explanation types and the concrete times when explanations should be given.
Familien(er)leben in Erwerbsarmut
Authors: Vogel Campanello Margot , Bombach Clara , Schneider Lea , Burri Melodie 
Published: June 2024

ZusammenfassungDie vom Schweizerischen Nationalfonds finanzierte Studie hat zum Ziel, die Auswirkungen von Erwerbsarmut auf das Familien(er)leben, insbesondere die damit verbundene Sorgearbeit sowie die Perspektive der Kinder und Eltern, zu untersuchen. Anhand eines qualitativen, multiperspektivistischen Vorgehens wird nach dem subjektiven Erleben der Familienmitglieder aus 42 Haushalten gefragt. Das Projekt generiert Wissen über die von Erwerbsarmut betroffenen Familien und gibt dabei Kindern eine eigene von den Eltern unabhängige Stimme. Es trägt zu einer Sensibilisierung prekärer Lebenslagen bei und schafft Voraussetzungen dafür, strukturelle Bedingungen des Aufwachsens von Kindern zu verbessern.
Modulation of Mouse Dendritic Cells In Vitro by Lactobacillus gasseri Postbiotic Proteins
Authors: Luongo Diomira , De Sena Vincenzo , Maurano Francesco , Rossi Mauro 
Published: June 2024

AbstractDifferent lactobacilli are probiotics for their beneficial effects that confer to the host. Recently, some of these effects were associated with released metabolic products/constituents (postbiotics). In the present study, the potential immunomodulatory capacity of the probiotic Lactobacillus gasseri OLL2809 cell-free supernatant (sup) was investigated in murine bone marrow-derived dendritic cells (DCs). Bacteria induced significantly higher expression of all examined cytokines than those induced by the stimulatory lipopolysaccharide (LPS) itself. On the contrary, sup only induced the anti-inflammatory IL-10 similarly to LPS, whereas IL-12 and IL-6 secretions were stimulated at a lower level. Moreover, sup reduced the surface expression of the analyzed co-stimulatory markers CD40, CD80, and CD86. Treatments of sup with different digestive enzymes indicated the proteinaceous nature of these immunomodulatory metabolites. Western blot and immunoadsorption analyzes revealed cross-reactivity of sup with the surface-layer proteins (SLPs) isolated from OLL2809. Therefore, we directly tested the ability of OLL2809 SLPs to stimulate specifically cytokine expression in iDCs. Interestingly, we found that all tested cytokines were induced by SLPs and in a dose-dependent manner. In conclusion, our results highlighted distinct immune properties between L. gasseri OLL2809 and its metabolites, supporting the concept that bacterial viability is not an essential prerequisite to exert immunomodulatory effects.
Ochrobactrum Bacterial Mediated pH Dependent Synthesis of Silver Oxide Nanoparticles
Authors: Ndulini Sinqobile Fanele , Mthembu Mathews Simon , Pullabhotla Viswanadha Srirama Rajasekhar 
Published: June 2024

AbstractGreen synthesis of nanoparticles from bacterial origin has become popular due to the advantages associated with it. Ochrobacrtum species supernatant of various pH (4, 7 and 10) was subjected to a filtered 1.0 mM AgNO3 solution, and the mixture was incubated at 37 ℃ for 48 h. This was done to reduce silver ions into elemental silver to form nanoparticles. Nanoparticles were harvested by centrifugation and were characterized using various analytical techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDX), transmission electron microscopy (TEM) and thermogravimetric analysis (TGA). Crystallographic studies revealed that the synthesized AgNPs were of face centered cubic crystalline phase. Silver nanoparticles with the average sizes of 55, 41 and 32 nm were obtained for Ochrobactrum anthropi silver nanoparticles synthesized at pH 4, 7 and 10 (OA4, OA7 and OA10) respectively. Ochrobactrum oryzae AgNPs synthesized at pH 4, 7 and 10 (OO4, OO7 and OO10) were 55, 37 and 43 nm respectively. A statistically significant particle size distribution was noted for both OA and OO AgNPs. Elemental analysis showed main elements to be C, O, Cl and Ag with Ag dominating. The bigger sizes of AgNPs produced under acidic conditions attributed to their ability to survive high temperatures up to 600 ℃.
Recent advances in solar still technology for solar water desalination
Authors: Tony Maha A. , Nabwey Hossam A. 
Published: June 2024

AbstractWater is signified as the gift of nature. However, modern societies are in tremendous need of fresh water due to the abundant industrial sector and factory growth that is leading to more and more such natural resource pollution. Also, there are global arid and desert areas where there are fewer regular rainfalls besides groundwater scarcity. Additionally, although there are abundant water bodies, most of them are not suitable for domestic irrigation, and especially for drinking purposes since they are brackish or saline water. Thus, water desalination is essential with no impact on the environment. Solar desalination is proven to be a sustainable and reasonable way for producing potable water. Numerous sorts of solar stills are introduced, and the most exhibited one is the conventional type of solar still, that is, so-called basin solar still. However, the low productivity of such solar still is signified as its major concern. Researchers have made their efforts to improve the productivity of solar stills through various designs and operating parameters. This detailed review is mainly focused on the various types of solar stills, their analyses and the status of several solar distillers. Throughout the entire work, it is confirmed and recommended to enhance the performance through advanced modifications that are also discussed. Such modifications are including advanced designs such as pyramid triangular solar stills, tubular, double basins and hemispherical and spherical solar stills. Also, integrated systems stills are recommended, such as connected solar stills with photo voltaic cells (PVC) or solar collectors to increase productivity.
Change in Microstructure, Mechanical Strength, Fire Resistance, and Radiation Attenuation Properties of Gypsum Plaster with Boric Acid
Authors: Arnavutoglu Emre , Arbag Huseyin , Koyuncu Dilsad Dolunay Eslek 
Published: June 2024

AbstractIn this study, the effect of boric acid addition on the microstructure of gypsum plaster was investigated to determine an environmentally friendly gypsum additive that may enhance mechanical strength, fire resistance, and X-ray radiation attenuation properties. The mechanical strengths of bare gypsum and boric acid-added (0–0.5% by weight with respect to gypsum amount) gypsum plasters were evaluated in terms of compressive and bending strengths. The effects of the different addition procedures of boric acid (0.1% by wt.) on the fire resistance of the gypsum plasterboard were also evaluated. X-ray radiation attenuation properties of boric acid-added (0.1% by wt.) gypsum plasterboard were investigated as well. XRD, ATR-FTIR, Helium pycnometer, N2 adsorption–desorption, and SEM analysis were performed to determine the microstructural properties of gypsum plaster. XRD and ATR-FTIR analysis revealed that boric acid did not change the calcium sulfate dihydrate structure of gypsum plaster. Whereas, Helium pycnometer, N2 adsorption–desorption, and SEM analysis showed that the physical properties of gypsum changed with an increase in pore volume, skeletal density, and particle size after boric acid addition. The increase in the pore volume and particle size decreased the mechanical strength of gypsum. However, boric acid addition on the gypsum plaster plate, especially using the spraying method, enhanced the fire resistance of gypsum. Additionally, boric acid slightly enhanced the X-ray radiation attenuation properties (0.7%) of the gypsum plasterboard.
The governance models vs. the development courses of the mining sector: cases of Indonesia and the Philippines
Authors: Liao Janet Xuanli , Zhang Weibo 
Published: June 2024

AbstractIndonesia and the Philippines have shared similar history, geological condition, and economic structure. Located in Southeast Asia, both countries have rich reserves of metallic minerals. They have also experienced changes of political system in the post-WWII era, from an authoritarian regime to a democracy, and have both pursued a neoliberal economic policy since the 1980s.​ However, the shared commonalities have not led to a similar development path of the mining industry in the two countries. Our research was aimed to reveal the key factors that caused the divergence of the mining development in Indonesia and the Philippines, from three main aspects: the evolution of the political system, the economic and mining policies adopted by the two governments, and the role of the mining regulations. The main question asked was that “Why did the similar political systems and economic policy fail to create a convergent path for mining development in the two neighbors?” The research has proved the validity of our hypothesis: the distinct political objectives and economic circumstances have impacted the implementation of the Neoliberal economic policy in the two countries. To a less extent, the scale of the mining industry in their respective economies and the different features of their respective colonial past were partially responsible as well.
Boron adsorption studies of poly(styrene-glycidyl methacrylate) latex: effect of modification agents
Authors: Tuncer Cansel , Işık Meliha 
Published: June 2024

AbstractPoly(styrene-glycidyl methacrylate) (PSGMA) latex was synthesized by emulsion polymerization method. PSGMA latex was modified with N-methyl-d-glucamine (NMDG), 1,2-bis(3-aminopropylamino)ethane (BAPE), N-(2-hydroxyethyl)ethylenediamine (HEA), and N,N'-dimethylethylenediamine (NMEA). The presence of N amount varying between 2.1 and 4.4% in the results of elemental analysis showed that the modification was successful. Boron adsorption studies were carried out using these modified latexes. The study was carried out using the curcumin method by UV–vis spectrophotometry. For the most effective adsorption process, at pH value of 9, the boron concentration was 10 ppm and the contact time was 60 min. It was found that latex modified with NMDG had a higher adsorption capacity (0.195 mmol/g) than other modified latexes. Particle sizes were determined by dynamic light scattering spectrometry and scanning electron microscopy (SEM) analyses. The particle diameter of PSGMA latex was found to be approximately 140 nm in SEM analysis and the particles were almost monodisperse. After PSGMA latex was modified with NMDG, BAPE, HEA, and NMEA agents and boron adsorption was performed, it was observed that the particle diameters increased to approximately 170, 270, 220, and 260 nm, respectively. An elemental analyzer was used to determine the %N of the structures. The %B2O3 of the structures was determined with a thermogravimetric analyzer. While thermal analysis studies showed that organic components were completely removed from the structure at 700 °C, residues ranging from 4.8 to 10.4% (%B2O3) were found in boron adsorption polymers. The %B amounts were determined with an inductively coupled plasma mass spectroscopy device. It was observed that the amount of adsorbed boron varied between 0.42 and 0.95%, and the highest amount of %B belonged to latex modified with NMDG due to its very simple structure and the location of the –OH groups.
Graphical Abstract
Impact of the Relational, Built, Community, and Policy/Political Environments on Immigrant Child Health: A Narrative Review
Authors: Zuckerman Anna , Nagin Perry , Ibrahim Anisa , Green Andrea E. , Dawson-Hahn Elizabeth E. 
Published: June 2024

Abstract
Purpose of Review
We summarize recent evidence describing how the health of first-generation immigrant children (FGIC) is influenced by the relational, built, community, and policy/political environments after migration to the United States.

Recent Findings
FGIC health is promoted and strengthened by family values, cultural ties, and positive peer relationships, while prior trauma, stressors in family relationships and discrimination detract from physical and mental health. While individual circumstances vary, some FGIC experience substandard built environments associated with poverty, including housing insecurity, food insecurity, and toxin exposures. Within community environments, FGIC receive support from their cultural communities, but may face challenges in navigating complex education and health systems. The policy/political environment often negatively impacts FGIC’s mental health and their ability to access medical and social services.

Summary
Healthcare provider awareness about health promoting and detracting factors for FGIC across multiple environments after migration can help inform comprehensive, trauma-informed care.
Update on Coagulation Monitoring in Liver Transplantation
Authors: Thiele Eryn L. , Forkin Katherine T. 
Published: June 2024

Abstract
Purpose of Review
This article provides an update on coagulation monitoring for patients undergoing liver transplantation and focuses on emerging data from the newest generation of viscoelastic testing devices.

Recent Findings
New generation, cartridge-based viscoelastic testing (VET) devices (TEG 6s, ROTEM sigma, Quantra with QStat cartridge) offer less inter-operator variability with greater ease of use and application at the point of care. Data on use of these cartridge-based VET devices in liver transplantation is limited.

Summary
The coagulopathy of liver disease affects both procoagulant and anticoagulant factors, resulting in a ‘rebalanced hemostasis’. The phases of liver transplantation present unique and dynamic challenges to blood management in these patients. VET is the preferred method of coagulation monitoring in liver transplantation with demonstrated benefits in decreased blood transfusion requirements, blood loss, and cost. Newer cartridge-based VET technologies have purported improvements over older technologies. More thorough investigation is needed in the use of these newer VET devices in liver transplantation.
Understanding watershed sources of pollution in Vinh Long Province, Vietnamese Mekong Delta
Authors: Bao Vo Quoc , Van Toan Pham , Van Tuyen Nguyen , Hoang Hong Minh , Du Le Van , Downes Nigel K. , Tri Van Pham Dang 
Published: June 2024

AbstractWe explore point source (PS) and non-point source (NPS) pollution impacts on surface water quality in Vinh Long Province, Vietnam. We used data from 60 surface water quality monitoring stations across dry, transitional, and wet seasons from 2017 to 2021, in addition to sampling data collected from 12 wastewater outlets from June to October 2021 to determine the sources of pollution loads. Surface water quality was assessed using both the water quality index (WQI) and the Vietnamese standards QCVN 08:2015, whilst cluster analysis (CA) and principal components analysis (PCA) were used to evaluate spatial variation and key influencing factors. We observed seasonal variation in surface water quality, with a decline in quality during the rainy season. Moreover, the water quality parameters such as chemical oxygen demand (COD), biochemical oxygen demand (BOD5), total nitrogen (TN), and total phosphorus (TP) frequently exceeded the QCVN 08:2015 standard. Across, the different monitoring fixed points and seasons, COD levels were found to range from 8.94 to 15.14 mg/L, while TN levels varied between 0.24 and 0.53 mg/L. The cluster analysis categorized the monitoring fixed points into three groups, based on their water quality parameters, while PCA identified four principal components that explain 69% of the variance, distinguishing between pollution sources and seasonal factors. Our findings emphasize that poor water quality in many areas is affected by non-point source pollution, underscoring the need for watershed and land management. The results and applied methodologies provide insights for watershed management, policy development, and adaptation, applicable to regions facing similar environmental challenges.