bluuebunny/crossref_metadata_2025_split huggingface dataset:
43: DESIGNING EVIDENCE BASED RISK ASSESSMENT SYSTEM FOR CANCER SCREENING AS AN APPLICABLE APPROACH FOR THE ESTIMATING OF TREATMENT ROADMAP
Authors: Maserat Elham , Safdari Reza , Aghdaei Hamid Asadzadeh , khoshsirat Alireza , Zali Mohammad Reza 
Published: May 2024

Background and aims:Prevention of cancer and risk assessment activity is highly information – intensively task, yet health care providers don't have appropriate technologies available to access, manage and interpret varied information. Also decision making modalities for cancer screening for many conditions and different stages have become increasingly complex. Evidence based systems facilitate decision making for the delivery of cancer screening services. The aim of this article is to designing evidence based Risk assessment system for cancer screening.Methods:This was a developing study. The first phase was a comparative study that performed by using secondary data extracted from literature review. Three courtiers (Canada, Australia and United States) were selected from 25 countries that are member in the international Cancer Screening Network (ICSN). National guidelines of colorectal cancer screening were approved in the next step. The scond phase was estimating of survival rate of covered populations. The Naive Bayes classifier was selected as one of the data mining technique for estimating. Finally evidence based hybrid decision support system was implemented. Programming language of designed web base system is Javascript. An integrated development environment (IDE) and database of system are respectively Jetbrain webstorm and MySQL.Results:In this study, screening evidence base system was surveyed of six dimensions. These dimensions were general specification, functions, technologies, data resources, users, manual and standards of screening information system. We approved four risk assessment guidelines (High risk, increased, average and low risk), clinical criteria for hereditary syndromes and roadmap of genetic and pathologic analysis. Designed intelligent hybrid system is integrated with registry system. This web base system has detected risk assessment groups by approved guidelines. This system determined 595 individuals with high risk, 185 individuals with increased risk, 20 individuals with average risk and 16 individuals with low risk up to July 30, 2016. Also screening recommendation screening of system was demonstrated by risk groups. Precision of system for detecting of risk groups was 100%. Evidence based system has estimated survival rates of covered populations with precision of 95.6%.Conclusion:This review was presented that evidence based system has improved real-time decision making process. This system has managed vast operation of cancer screening. One of the suggestions for future research is the national integrated evidence based network for all cancers.
47: DOWNSIZING OF PUBLIC HOSPITALS IN TABRIZ AND ARDABIL CITIES
Authors: Mousazadeh Yalda , beyrami Hosein Jabbari 
Published: May 2024

Background and aims:many countries use different strategies for example downsizing in order to optimal use of resources and reduce costs. Therefore, this study was implemented to evaluate of different downsizing methods in public hospitals of Tabriz and Ardabil cities.Methods:This study was a descriptive study that was conducted in 2015 and 2016 in order to identify of downsizing methods in public hospitals in Tabriz and Ardabil cities. A self-made questionnaire was used to data collection. Its content validity was approved by five university professors in health economic and health services management. SPSS 20 software and descriptive statistics was used for data analysis.Results:A total of 13 of downsizing methods, 11 methods were used in Tabriz hospitals and 6 methods were used in Ardabil hospitals. Outsourcing and cooperation between hospitals were the most frequent methods. Cost reduction was the most important goal of downsizing. Also, performance evaluation was the most important control mechanism after downsizing.Conclusion:The findings showed that the downsizing method specially Outsourcing and cooperation have been used widely in public hospitals of Tabriz and Ardabil universities of medical sciences. It seems precise planning, variety and hospital circumstances are important factors in achieving the downsizing goals.
49: EFFECT OF GREEN TEA ON LIVER ENZYMES IN RAT HEPATIC FIBROSIS MODEL
Authors: Dorreyatim Seyed Sina , Bavil Fariba Mirzaee 
Published: May 2024

Background and aims:Green tea is a popular beverage in the world, especially Asia. Beneficial effects of it have studied in the prevention and treatment of diseases. There are few studies about impact of green tea on hepatic diseases, thus we decided to investigate its impact on liver fibrosis.Methods:Forty male wistar rats were randomly divided into five groups: control group, GTE (green tea extract) group that received GTE powder dissolved in distilled water at doses of 125 mg/kg body weight orally for four weeks, fibrosis group, that was injected carbon tetrachloride (CCl4)1ml/kg/IP (diluted in corn oil), 3 times per week for 4 weeks, GTE+CCl4 group that received GTE and CCl4 at the same time and corn oil group was administered corn oil 1 mL/kg body weight three times a week for four weeks. In the end of study, the rats were sacrificed to measure serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP).Results:The fibrosis group showed an increase in ALT, AST and ALP levels in comparison with the control group (P<0.01). Green tea reduced all of enzymes in fibrosis model significantly (P<0.05). GTE and corn oil had no effect on the enzymes in normal conditions.Conclusion:According to obtained results, GTE decrease liver enzymes in situations fibrosis. So it is suggested that the use of green tea can be useful in reduction of liver injuries.
68: FACTORS AFFECTING THE KNOWLEDGE TRANSLATION: A QUALITATIVE STUDY AMONG FACULTY MEMBERS
Authors: Kakemam Edris , Sokhanvar Mobin , Arab-Zozani Morteza , Naderi Bahar 
Published: May 2024

Background and aims:When the results of researches be used in the field and suggested ideas come into force, it can be said the purpose of research was achieved. This study was conducted to extract the factors affecting the knowledge translation from faculty member`s perspective.Methods:This qualitative study was done in 2016 among faculty members of Tehran University of Medical Sciences. The sample number was based on data saturation. So the semi-structured interview was conducted with 18 faculty members. The interview set between 45–60 minutes. Note taking and audio type were used to data gathering. Content analysis was done by using MAXQDA-10.Results:The mean interview duration was 52 minutes. The 55.5 percent of participants were men and mean age of all participates was 42.6 years. 41 original codes were obtained from the review of transcripts. In the second step those codes were placed in 11 main categories based on codes content convergence. Finally, 5 main themes were extracted from categories combination based on theirs overlap. These themes included database and information availability, social and organizational culture, social capital, personal factors, and organizational factors.Conclusion:Knowledge translation is necessary to utilize studies result. In this regard attention to affecting factors is important to deal properly and successful knowledge translation.
83: IS DIFFERENT OF THE NURSES AND NURSING STUDENTS' PERSPECTIVE ABOUT PROFESSIONAL VALUES?
Authors: Poorchangizi Batool , Farokhzadian Jamileh , Borhani Fariba , Abbaszadeh Abbas , Mirzaee Moghaddameh 
Published: May 2024

Background and aims:Each professional group has its basic standards which are called the professional values and are considered the guides and motivation for individual professional behavior. Commitment to values is very important issue in health care that changing rapidly. The aim of this study was to examine the professional values from perspective of nurses and nursing students.Methods:This study was a descriptive-analytical research. By stratified random sampling method participated 250 nurses from hospitals affiliated to University of Medical Sciences and 100 baccalaureate nursing students of a school in Kerman, Iran in 2016. Data were collected by Persian version of the Nurses Professional Values Scale-Revised (NPVS-R) Weis and Schank. This instrument consisted 26-item in the five dimensions (Caring, Activism, Trust, Professionalism and Justice) at five- point Likert-Scale format (from not important to very important). Data analyzed by SPSS version 19.Results:The results showed that there was no significant difference between the mean scores of professional values of nurses (102/57±11/94) and students (101/79±12/42). The most important values of nurses and students, included “maintain confidentiality of patient” (from caring dimension), “safeguard patient's right to privacy” (from caring dimension), and the least important values in both groups were related to activism and professionalism dimensions for example participating in nursing research and/or implement research findings appropriate to practice and participating in peer review.Conclusions:The high total score of professional values of nurses and nursing students in this study represent most orientation nurses. Recommended to educators to pay more attention to these values in theoretical and clinical training of nursing students in particular values associated with social and political issues that there are related to activism and professionalism dimensions until through the teaching these values helped to promotion the nursing profession and also emphasized to the role continuing education in learning and instill professional values to nurses, according to emerging ethical challenges.
87: KNOWLEDGE, ATTITUDE, AND PRACTICE OF EVIDENCE-BASED MEDICINE AMONG PHYSICIANS: A SYSTEMATIC REVIEW
Authors: Barzkar Farzaneh , Baradaran Hamidreza 
Published: May 2024

Background and aims:Evidence-based practice, defined as the systematically reviewing, appraising and using clinical research findings to aid the delivery of optimum clinical care to patients, has been encouraged among physicians worldwide. We conducted a systematic review of articles assessing knowledge, attitude, and practice (KAP) of graduate physicians towards evidence-based medicine (EBM) and the barriers to the implementation of EBM.Methods:Medline, Google Scholar, and ERIC were searched systematically with appropriate search terms up to February 2016. References of the articles detected by search were screened for any missed articles evaluating knowledge, attitude, or practice of EBM among physicians. Studies with a qualitative design and those merely evaluated implementation of clinical practice guidelines were excluded based on abstracts. The studies were assessed regarding their instruments.Results:Out of 46 articles finally included in our study, 15 studies evaluated the study parameters among primary care physicians and the remaining studies evaluated residents (n=12) and specialists. The most commonly used (n=23) questionnaire was the one developed by McColl et al in 1998 which evaluated self-reported awareness, attitudes, and barriers towards EBM. Regarding the tools that assess knowledge, attitude, and practice of EBM, we found that the current questionnaires may have relatively adequate strength to measure attitude, but are subjective and indirect measures of awareness rather than knowledge. Moreover, some of the less commonly used tools were more objective and practical than the ones most commonly used.The physicians have a generally positive attitude towards EBM and most of them believe that its implementation improves patient care. However their self-reported awareness and knowledge regarding common terms used in EBM and the main databases is generally poor. Both knowledge and attitude have improved through years after the introduction of EBM and specialists generally have a more positive attitude and better knowledge towards EBM than primary care physicians.Conclusion:Findings from our review indicate that in spite of the increasingly more positive attitude towards EBM among physicians, their knowledge and practice remain relatively poor. Also, there is need for updated more objective tools for the assessment of EBM knowledge, attitude, and practice among physicians
9: ADAPTATION OF PREGNANCY RISK ASSESSMENT MONITORING SYSTEM (PRAMS) AND PROVIDE A MODEL ON IT
Authors: Kharaghani Roghieh , Shariati Mohammad , Keramat Afsaneh , Yunesian Masud , Moghisi Alireza 
Published: May 2024

Background and aims:A surveillance system helps to detect epidemics and the pattern of the problems incidence in the community and it is essential part of evidence based decision making process. This study aimed to adapt of PRAMS and provide a model on it.Methods:This study was performed in 7 steps as follows: Surveillance systems in pregnancy were reviewed and appropriate system was selected for Iran by nominal group technique. Two comparative studies were conducted to determine the similarities and differences between Iran and the selected community. PRAMS method and system were adapted based on the results of the comparative studies and experts opinions. The study tool was adapted. A field trial was conducted to assess adapted PRAMS feasibility based on TELOS (technical, economic, legal, operational, and schedule) model in the city of Shahriar, located in the west of Tehran, and to compare data collection methods. Then, based on the results and consultation with related executive managers, the final model of PRAMS was suggested for Iranian health system.Results:Review of the surveillance systems in pregnancy, identified six models. The results of the nominal group technique showed that, the appropriate model for Iran is PRAMS. Based on the comparative studies and expert opinions, the appropriate system and method for program was as follows: the sampling frame was composed of data in thyroid screening forms and hospital records, the sampling method was systematic, data collection methods were home and phone based surveys, and participants were women within 2 to 6 months postpartum who had a live or still birth. The study tool was adapted. Thirty-seven health volunteers collected the data in this study (technical feasibility). Any home based completed questionnaire cost 2.45 and a phone cost 1.89 USD. Many indices were achieved from the study, which were worth much more than the expenses (economic feasibility). The project was consistent with legal requirements (legal feasibility). There was no statistically significant differences in mother's participation rate between phone (90.9%) and home visit (92.8%) groups and about 90.8% of different sections of the questionnaire were completed (operational feasibility). All data collection processes took 35 days (schedule feasibility). Based on the study results, the appropriate model of surveillance system was suggested with the goals of reducing infant morbidity and mortality and promoting maternal health by influencing maternal and child health programs, and maternal behaviors during pregnancy and early infancy.Conclusion:The adapted PRAMS could be considered feasible in Iran and may offer a potential solution to some data deficits in maternal and child health indicators. Moreover, by monitoring pregnancy risks and outcomes, we can assess, analyses, and modify the current prenatal care program through PRAMS widespread and periodic implementation.
97: POSITIVE RELIGIOUS COPING AS A PREDICTOR FOR IMPROVEMENT OF MENTAL HEALTH AMONG UNIVERSITY STUDENTS
Authors: Taheri-Kharameh Zahra , Hazavehei Mohammad Mahdi 
Published: May 2024

Background and aims:Religious Coping is known as a main resource influencing for adjustment and managing appropriately the problems and stressors, that it seems to be an inseparable component in mental health literature in recent years. This study was carried out to investigate the religious Coping and mental health in the students of the Qom University of Medical Sciences.Methods:In this descriptive and analytical study, 138 students of the Qom University of Medical Sciences were selected via random sampling methods. These students completed the Brief religious Coping scale (RCOPE) and General Health Questionnaire (GHQ-12). Data were analyzed in SPSS 16 software environment utilizing descriptive statistics and the Independent t-test, ANOVA, Pearson correlation coefficient and regression analysis.Results:Mean and standard deviations of religious coping well-being and mental health scores were 24.63±2.07 and 12.62±6.39. 47.8 percent of students have higher mean score in positive religious coping and the portion about negative religious coping was 48.5 percent. The results of multiple liner regression showed that positive religious Coping was significantly associated with general health (β=0.37;p=0.0001) related to the mental health component as well as controlling for demographic variables. There were no significant correlations between negative positive religious and psychological distress.Conclusion:The findings indicated that positive religious coping was associated significantly with better general health spatially mental health of students. Another word, positive religious Coping was respectively the most important factor for religious-spiritual components which may improve mental health in students.
Lipid profile alterations in non-infectious uveitis: correlation with quantitative optical coherence tomography angiography parameters
Authors: Shen Junhui , Qin Guangming , Feng Lei 
Published: May 2024

Background/aimsLipid profiles have been changed in numerous chronic conditions. The impact of uveitis on lipid metabolism remains unclear.MethodsThis is a cross-sectional study included 416 patients with non-infectious uveitis (NIU) and 416 healthy subjects. Standard techniques were used to measure total cholesterol (TC), triglycerides (TG), high-density lipoprotein-cholesterol (HDLc), low-density lipoprotein-cholesterol (LDLc) levels. Quantitative optical coherence tomography angiography (OCTA) parameters were obtained from 500 eyes in each group. Correlation analysis examined the relationship between lipid profile and OCTA parameters.ResultsPatients with NIU exhibited significantly elevated TC, TG and LDLc levels compared with controls (p=0.003; p<0.001; p<0.001, respectively). Subgroup analysis revealed that HDLc was significantly lower in Behçet’s disease (p=0.024) compared with controls. Vascular density (VD) in the superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaris and optic disk were significantly decreased in NIU eyes (p<0.05, respectively) compared with controls. HDLc exhibited a significant negative correlation with VDs in the whole and parafovea SCP (r=−0.489, p=0.008; r=−0.480, p=0.0026, respectively), while LDLc showed a significant positive correlation with VDs in the whole and parafovea DCP in NIU patients (r=0.576, p=0.032; r=0.267, p=0.034, respectively).ConclusionsThe lipid profile is altered in NIU, and there are correlations between HDLc and LDLc levels and VD as measured by OCTA. Lipid profile analysis may offer valuable insights into evaluating vascular and metabolic aspects of NIU.
Use of digital technologies for staff education and training programmes on newborn resuscitation and complication management: a scoping review
Authors: Horiuchi Sayaka , Soller Tasmyn , Bykersma Chloe , Huang Shan , Smith Rachel , Vogel Joshua P 
Published: May 2024

BackgroundPoor-quality care is linked to higher rates of neonatal mortality in low-income and middle-income countries (LMICs). Limited educational and upskilling opportunities for healthcare professionals, particularly those who work in remote areas, are key barriers to providing quality neonatal care. Novel digital technologies, including mobile applications and virtual reality, can help bridge this gap. This scoping review aims to identify, analyse and compare available digital technologies for staff education and training to improve newborn care.MethodsWe conducted a structured search of seven databases (MEDLINE (Ovid), EMBASE (Ovid), EMCARE (Ovid), Global Health (CABI), CINAHL (EBSCO), Global Index Medicus (WHO) and Cochrane Central Register of Controlled Trials on 1 June 2023. Eligible studies were those that aimed to improve healthcare providers’ competency in newborn resuscitation and management of sepsis or respiratory distress during the early postnatal period. Studies published in English from 1 January 2000 onwards were included. Data were extracted using a predefined data extraction format.ResultsThe review identified 93 eligible studies, of which 35 were conducted in LMICs. E-learning platforms and mobile applications were common technologies used in LMICs for neonatal resuscitation training. Digital technologies were generally well accepted by trainees. Few studies reported on the long-term effects of these tools on healthcare providers’ education or on neonatal health outcomes. Limited studies reported on costs and other necessary resources to maintain the educational intervention.ConclusionsLower-cost digital methods such as mobile applications, simulation games and/or mobile mentoring that engage healthcare providers in continuous skills practice are feasible methods for improving neonatal resuscitation skills in LMICs. To further consider the use of these digital technologies in resource-limited settings, assessments of the resources to sustain the intervention and the effectiveness of the digital technologies on long-term health provider performance and neonatal health outcomes are required.
Predictive value of laboratory indicators for in-hospital death in children with community-onset sepsis: a prospective observational study of 266 patients
Authors: Liu jing , Hui Qin , Lu Xiuxiu , Li Wei , Li Ning , Chen Yuanmei , Zhang Qi 
Published: May 2024

Background and objectivesThis study aimed to identify predictors of sepsis-associated in-hospital mortality from readily available laboratory biomarkers at onset of illness that include haematological, coagulation, liver and kidney function, blood lipid, cardiac enzymes and arterial blood gas.MethodsChildren with sepsis were enrolled consecutively in a prospective observational study involving paediatric intensive care units (PICUs) of two hospitals in Beijing, between November 2016 and January 2020. The data on demographics, laboratory examinations during the first 24 hours after PICU admission, complications and outcomes were collected. We screened baseline laboratory indicators using the Least Absolute Shrinkage and Selection Operator (LASSO) analysis, then we constructed a mortality risk model using Cox proportional hazards regression analysis. The ability of risk factors to predict in-hospital mortality was evaluated by receiver operating characteristic (ROC) curves.ResultsA total of 266 subjects were enrolled including 44 (16.5%) deaths and 222 (83.5%) survivors. Those who died showed a shorter length of hospitalisation, and a higher proportion of mechanical ventilation, complications and organ failure (p<0.05). LASSO analysis identified 13 clinical parameters related to prognosis, which were included in the final Cox model. An elevated triglyceride (TG) remained the most significant risk factor of death (HR=1.469, 95% CI: 1.010 to 2.136, p=0.044), followed by base excess (BE) (HR=1.131, 95% CI: 1.046 to 1.223, p=0.002) and pH (HR=0.95, 95% CI: 0.93 to 0.97, p<0.001). The results of the ROC curve showed that combined diagnosis of the three indicators—TG+BE+pH—has the best area under the curve (AUC) (AUC=0.77, 95% CI: 0.69 to 0.85, p<0.001), with a 68% sensitivity and 80% specificity.ConclusionLaboratory factors of TG, BE and pH during the first 24 hours after intensive care unit admission are associated with in-hospital mortality in PICU patients with sepsis. The combination of the three indices has high diagnostic value.