bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Exposure of Coastal Inundation from Storm Surge in the Northern part of Malaysian Borneo
Authors: Osman N F , Saleh E , Sentian J 
Published: June 2024

Abstract
Coastal communities heavily rely on marine resources for their livelihoods. The rising occurrence of extreme weather events have affected both the coastal ecosystems and socio-economic activities. One of the most prevalent extreme events in Malaysia is the storm surge. This study aims to assess the extent of coastal inundation based on three storm surge scenarios (categories by Meteorological Department of Malaysia) and to determine the risk exposure ranking of nine study sites. Field trips and interviews were conducted from March 2020 to March 2023 in Kudat located at the northern part of Malaysian Borneo. One hundred respondents were surveyed using semi-structured open-ended questionnaires to evaluate the risk exposure of coastal inundation caused by storm surges. The findings revealed that Category 1 flooded certain sites of west (Kimihang) and east (Tajau Laut) sides of Kudat. The Category 2 have significantly flooded one site in the west side (Simpang Mengayau) of Kudat. While, for Category 3 of coastal inundation affected two sites in east sides of Kudat (Tanjong Kapor and Landung Ayang). These two sites in east sides of Kudat also experienced a high level of risk exposure due to the lack of diverse coastal ecosystems and high population density. While three sites in west side of Kudat (Kimihang, Kelambu and Simpang Mengayau) faced significant impacts on social services, particularly within the tourism sector. Despite relying on multiple livelihoods, these sites were susceptible to storm surges. Additionally, the increasing development for tourism purposes posed a threat to the richness of the ecosystem. This study suggests that certain sites in east side of Kudat (Tanjong Kapor and Landung Ayang) are highly exposed to risk and require measures for adaptation and mitigation.
Instrumentation for Monitoring and Early Warning of Tidal Flood Using ESP32S2 Microcontroller and A01NYUB Ultrasonic Sensor in Tambakrejo, Semarang
Authors: Susanti A F S , Putranto R T , Rahmadani M A , Mustaqim I , Saliyo A D S , Sazidah H , Hutahaean C A , Putri S A , Iriani R N , Mulyawan Z W , Kurniawan M W , Alimatunnisa I , Ginanjar S , Adiningsih S , Wirasatriya A , Kunarso  , Sugianto D N , Trianto A 
Published: June 2024

Abstract
A tidal flood early warning system is crucial to minimize the impact and loss in tidal flood-prone areas. This research proposes an instrumentation and information system for tidal flood early warning monitoring by optimizing tidal data in the local area. The efficiency of the instrumentation depends on the accuracy of the sensors installed. This research presents the testing and application of The A01NYUB ultrasonic sensor with The ESP32S2 microcontroller for real-time technology-based water level monitoring and The Internet of Things concept. The collected sensor data is analyzed with an algorithm that has also been proposed in this research. The results show that the ultrasonic sensors can provide a reliable and adequate tide monitoring scheme with an accuracy of RMSE value of 0.08943 and bias value of – 2×10−16. The developed system provides early warning when the sea level reaches 260-280 cm with the MSL datum reference value range of -20 cm to 40 cm. The system has been tested at the Fisherman Boat Harbor, Tambakrejo, Semarang, Central Java, Indonesia. The test has shown the system’s accuracy and has proven that the developed system will help minimize the impact of the tidal flood disaster.
Characteristics of internal waves in the Bali Sea from Sentinel-1A data and ocean modeling
Authors: Lukman A , Atmadipoera A S , Nugroho D , Harsono G 
Published: June 2024

Abstract
Internal waves (IWs) that propagate into the Bali Sea are supposed to originate from the generating sill area in the southern part of the Lombok Strait. This study aims to investigate surface features and mechanism of IWs formation and propagation into the Bali Sea. The datasets are acquired from the Sentinel-1A imageries and CROCO model simulation. The results showed that solitary wave packets are spread over two areas: near Lombok Strait as generating area, and in the western and northern parts of the Bali Sea as propagating area. The length of IWs crests increased as they moved into the propagation area. The model showed that mixed semidiurnal tidal currents near the sill flow northward (southward) alternately during the flood (ebb) tidal period, resulting in the pycnocline deepening down to ~400 m near the northern sill area during the flood tide. Furthermore, the model demonstrated an alternating upward and downward movement of vertical currents components, associated with propagation of IWs’ crests and troughs along IWs pathway.
Silver nanoparticles alleviate the impact of soil contamination and wastewater irrigation on rosemary plants: modulating of gene expression and secondary metabolites
Authors: Al Kashgry Najla Amin T , Darwish Hadeer , Aljomiha Nouf A , Alharthi Sarah , Alayafi Aisha A M , Fallatah Ahmed M , El-Deeb Bahig A , Abd El-Gawad Hany G , Hewidy Mohammed , Al-Harbi Nadi Awad , Al-Qahtani Salem Mesfir , Alotaibi Modhi O , Algotiml Rabaa Abdullah , Noureldeen Ahmed 
Published: June 2024

Abstract
A number of obstacles, including irrigated wastewater and soil contamination, arise in the growth of aromatic and medicinal plants. This study aimed to reduce the effects of contaminated soil and wastewater irrigation on rosemary (Rosmarinus officinalis L.) plants by using biosynthesized silver nanoparticles (AgNPs) produced by the ginger (Zingiber officinale) plant extract. The AgNPs were characterized using Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR). The experimental design involved three distinct groups of plants: one group was irrigated with regular tap water, another group was rooted in soil contaminated by sewage-wastewater and irrigated with processed wastewater, and the final group consisted of plants grown in wastewater-contaminated soil, irrigated with processed wastewater, and sprayed with 200 mM l−1 AgNPs. The study also examined the impact of different treatments on gene expression and secondary metabolite levels in rosemary plants. According to HPLC investigations, nineteen phenol compounds and flavonoids were identified in a methanolic extract of rosemary that was grown in contaminated soil, irrigated with wastewater, and sprayed with AgNPs. Plants treated with wastewater and nanoparticles produced quantities of secondary compounds, including resvertol, vanillic acid, and gallic acid with 1.11, 0.15, and 0.01 mg g−1 respectively, which are all regarded as significant antioxidants employed in the pharmaceutical industry. Hexokinase synthase (HK), geranyl diphosphate synthase (GPPS), and linalool synthase (LS) coding genes were found to have highly expressed expressions when plants grown in contaminated soil, wastewater-irrigated plants, and nanoparticle-sprayed plants, respectively, at a 23.2- and 5.54-fold level, where the HK gene was 8.7 times more strongly expressed. Conversely, plants grown in contaminated soil and irrigated with treated wastewater showed downregulation of these genes. Conclusively, using silver nanoparticles significantly reduced the influence of wastewater pollution on secondary metabolites in rosemary plants, which was increased by the gene expression results and was completely consistent with HPLC analysis.
Horses, gender, and (queer) masculine desire, or how experimental found footage film recycles three Hollywood films
Authors: Boczkowska Kornelia 
Published: June 2024

Abstract
Although the experimental found footage film recycles Hollywood films so that the outcome may radically differ from the original story, there are no accounts on how it adapts images from mainstream cinema to represent human–animal relations, linking to gender and masculinity. To fill this gap, I discuss how experimental film Horsey recycles footage from three Hollywood productions—Reflections in a Golden Eye, The Swimmer, and The Black Stallion—to construct a new narrative, which displays a very close conformity to the prior text, shifting the focus to human–horse interactions. Raising questions about the traditional understanding, scope, and limits of adaptation in avant-garde film studies, Horsey fits in with the broader tradition of cinematic recycling of mainstream cinema as it exemplifies intertextuality as a direct form of quotation, taking quotation as appropriation through cuts, detournement, compilation and free association. Particularly, following Guy Barefoot’s understanding of adaptation as an intertextual form of recycling, Horsey is distinctive in its sole use of found footage from the three Hollywood films as it fully acknowledges the recycled material, strongly alluding to the original stories, and simultaneously re-processes them through a collage of pre-used footage, slow motion, washed-out colours, and an altered soundtrack. Despite appearing to merely extract images and sounds from Reflections, The Swimmer, and The Black Stallion, Horsey emerges as a productive site for recycling Hollywood cinema, placing it into new contexts and audio-visual configurations and offering more complex, engaging ways of looking at how humans connect to horses.
High Blood Pressure Is Associated With Lower Brain Volume and Cortical Thickness in Healthy Young Adults
Authors: Won Junyeon , Ashley John , Cardim Danilo , Vongpatanasin Wanpen , Zhang Rong 
Published: June 2024

Abstract

BACKGROUND
High blood pressure (BP) in middle-aged and older adults is associated with lower brain volume and cortical thickness assessed with structural magnetic resonance imaging (MRI). However, little evidence is available on young adults. We investigated the associations of high BP with brain volumes and cortical thickness in healthy young adults.

METHODS
This cross-sectional study included 1,095 young adults (54% women, 22–37 years) from the Human Connectome Project (HCP) who self-reported not having a history of hypertension or taking antihypertensive medications. Brachial systolic (SBP) and diastolic BP (DBP) were measured with a semi-automatic or manual sphygmomanometer during study visits. Structural MRI was used to measure gray matter (GM) and white matter (WM) volume and mean cortical thickness. Associations of BP and hypertension stage with total and regional brain volumes and cortical thickness were analyzed using linear regression and analysis of covariance (ANCOVA) after adjusting for age, sex, education years, body mass index (BMI), smoking, alcohol consumption history, zygosity, and total intracranial volume.

RESULTS
SBP and DBP were (mean ± SD) 123.6 ± 14.2 and 76.5 ± 10.6 mm Hg, respectively, (n = 1,095). High DBP was associated with lower total GM (P = 0.012), cortical GM (P = 0.004), subcortical GM (P = 0.012), and total WM volumes (P = 0.031). High SBP and DBP were associated with lower regional cortical volume and cortical thickness.

CONCLUSIONS
These findings suggest that high BP may have deleterious effects on brain health at the early stage of adulthood.
Adaptive Steroid Tapering Impedes Corticosteroid-free Remissions Compared with Forced Tapering in Clinical Trials of Ulcerative Colitis
Authors: Narula Neeraj , Hamam Hasan , Liu Jasmine , Wong Emily C L , Marshall John K , Jairath Vipul , Hanauer Stephen B , Reinisch Walter , Dulai Parambir S 
Published: June 2024

Abstract

Introduction
It is unclear if steroid tapering protocols can affect clinical trial outcomes in ulcerative colitis [UC], particularly fixed versus adaptive steroid tapering. Fixed steroid tapering involves incremental dose decreases at prespecified intervals, and adaptive steroid tapering uses investigator discretion as determined by the patient’s response.

Methods
In this post-hoc analysis from six clinical trials of UC [VARSITY, ACT 1, PURSUIT, GEMINI1, OCTAVE, and ULTRA2], responders to induction therapy with baseline corticosteroid use were considered as the primary population of interest. Adjustments were made to account for treat-through versus re-randomisation designs, and multivariate regression was performed to account for other potential confounding variables. The primary outcome was corticosteroid-free clinical remission [CR] at 1 year, and secondary outcomes were CR and endoscopic improvement.

Results
There was a total of 861 patients who had achieved clinical response after induction and were using corticosteroids. Within multivariate analysis, patients using adaptive steroid tapering regimens were less likely to achieve corticosteroid-free CR at 1 year (odds ratio [OR] 0.66 [95% confidence interval, CI, 0.48-0.92], p = 0.015) but had increased odds for achieving CR at 1 year (OR 1.9 [95% CI 1.43-2.52], p &lt; 0.001). The steroid tapering regimen was not associated with achievement of endoscopic improvement at 1 year.

Conclusions
Among patients with UC on corticosteroids in clinical trials, patients using adaptive steroid weaning regimens were less likely to achieve corticosteroid-free CR at 1 year but more likely to achieve CR at 1 year. Consideration should be given to implementing mandatory fixed steroid weaning protocols in future clinical trials of UC.
Global Englishes-oriented teacher education: lasting shifts
Authors: Schreiber Brooke R , Jansz Mihiri 
Published: June 2024

Abstract
Despite a growing body of research demonstrating the pluralistic nature of English today, ELT globally still tends to uphold traditional ‘native-speaker’ norms. A Global Englishes language teaching (GELT) approach to teacher education is one way of breaking down that gap, yet it is not well known how the effects of this approach might hold up over time. This article reports on a study of three Sri Lankan teachers who participated in a GELT-oriented pedagogic innovation in 2017 communicating with a diverse group of speakers in the United States. Using interview data, this article discusses how, three years later, their experiences may have affected their pedagogic beliefs and practices. The teachers reported changes such as greater tolerance for informal language, a desire to bring ‘real world’ communication into language classrooms, and an openness to diversity in pronunciation as a means of reducing student anxiety about speaking. These small, meaningful shifts support the value of small-scale GELT teacher education innovations in the long term.
Home Through Their Eyes: A Qualitative Exploration of the Meaning of Home for Persons With Dementia and Impact of Physical Environment During Meaning-Making
Authors: Wang Wenjin , Roumell Elizabeth , Xu Chuanyue , Lu Zhipeng 
Published: June 2024

Abstract

Objectives
This study aimed to examine the meaning of home for persons with dementia and the role of the physical environment during their meaning-making process. In response to a growing number of persons with dementia, there has been a strong advocacy for prioritizing the development of dementia-friendly environments within design practice and research agendas, for which “home” has become one of the important loci. However, of the limited studies on the meaning of home from the perspective of those individuals who continue to live in their own homes after developing dementia, even fewer addressed this issue within the Chinese context.

Methods
Five dyads, persons with dementia and their family caregivers, participated in the qualitative phenomenology study. Ten home visits–2 visits per dyad–were conducted, during which interview data, photographs, and field notes were collected. Phenomenological analysis was applied within and across the data sets.

Results
Three key themes emerged—“Three Dimensions of Home” revealed that “home” goes beyond physical residence and immediate family connections, including meaningful objects and places, enduring relationships, self-identity, and lived experiences.; “The Impact of Physical Environment” and “The Impact of Cognitive Impairment” showed the complex interactions between the environment, cognitive impairment, and meaning-making.

Discussion
An exploration of the essence of meaning of home within the Chinese context, in person–environment relationships with dementia progression, and implications for future research and practice on dementia-related environments and care were further discussed. This study contributes insights into enhancing the well-being of persons with dementia and benefiting their caregivers.
Target Trial Emulation: Improving the Quality of Observational Studies in Inflammatory Bowel Disease Using the Principles of Randomized Trials
Authors: Honap Sailish , Danese Silvio , Peyrin-Biroulet Laurent 
Published: June 2024

Abstract
The past decade has seen a substantial increase in the number of randomized controlled trials (RCTs) conducted in inflammatory bowel disease (IBD). Randomized controlled trials are the gold standard method for generating robust evidence of drug safety and efficacy but are expensive, time-consuming, and may have ethical implications. Observational studies in IBD are often used to fill the gaps in evidence but are typically hindered by significant bias. There are several approaches for making statistical inferences from observational data with some that focus on study design and others on statistical techniques. Target trial emulation is an emerging methodological process that aims to bridge this gap and improve the quality of observational studies by applying the principles of an ideal, or “target,” randomized trial to routinely collected clinical data. There has been a rapid expansion of observational studies that have emulated trials over the past 5 years in other medical fields, but this has yet to be adopted in gastroenterology and IBD. The wealth of nonrandomized clinical data available through electronic health records, patient registries, and administrative health databases afford innumerable hypothesis-generating opportunities for IBD research. This review outlines the principles of target trial emulation, discusses the merits to IBD observational studies in reducing the most common biases and improving confidence in causality, and details the caveats of using this approach.
Burrowing Constrains the Phenotypic Diversity of Fossorial Crayfish
Authors: Delekta Emmy M , Kolmann Matthew A 
Published: June 2024

Synopsis
Strong selective pressure on phenotype can arise when habitat transitions fundamentally alter the physical media in which animals live, such as the invasion of land by lobe-finned fishes and insects. When environmental gradients differ drastically among habitats and multiple lineages transition between these habitats, we expect phenotypic convergence to be prevalent. One transition where widespread convergence has been observed is the shift from aboveground to subterranean environments in fossorial animals. Subterranean environments are low-light, confined spaces and tend to be hypoxic or anoxic, not to mention that the act of burrowing itself demands morphological specializations for excavation. Research suggests burrowing promotes morphological convergence in crayfish, with non-burrowing forms having a dorsoventrally compressed carapace and long, slender claws (chelae), while primary burrowing forms have a dorsolaterally compressed carapace and shorter, more powerful claws. However, earlier ecomorphological comparisons relied on qualitative rather than quantitative assessments of phenotypic differences. This study tested for convergence in North American crayfishes using a geometric morphometric approach. We photographed the carapace and claw for representative species across 13 North American genera. We hypothesized that crayfishes that occur in similar habitats and exhibit similar burrowing behaviors, would converge in their carapace and claw shapes. We found evidence for convergence in carapace and claw morphologies in burrowing crayfishes. However, claw phenotypes did not converge as strongly as carapace shape, an example of “imperfect” or “incomplete” convergence we attribute to the multiple competing demands on claw form and function. We argue that nuances in habitat characteristics, like soil type or compaction, make complete convergence unlikely for range- and dispersal-limited fossorial crayfishes.
miRNome Profiling of Extracellular Vesicles in Patients With Severe COVID-19 and Identification of Predictors of Mortality
Authors: Sánchez-de Prada Laura , García-Concejo Adrián , Tamayo-Velasco Álvaro , Martín-Fernández Marta , Gonzalo-Benito Hugo , Gorgojo-Galindo Óscar , Montero-Jodra A , Peláez María Teresa , Martínez Almeida Iciar , Bardají-Carrillo Miguel , López-Herrero Rocío , Román-García Patricia , Eiros José María , Sanz-Muñoz Iván , Aydillo Teresa , Jiménez-Sousa María Ángeles , Fernández-Rodríguez Amanda , Resino Salvador , Heredia-Rodríguez María , Bernardo David , Gómez-Sánchez Ester , Tamayo Eduardo 
Published: June 2024

Abstract

Background
Extracellular vesicles (EVs), containing microRNAs (miRNAs) and other molecules, play a central role in intercellular communication, especially in viral infections caused by SARS-CoV-2. This study explores the miRNA profiles in plasma-derived EVs from patients with severe COVID-19 vs controls, identifying potential mortality predictors.

Methods
This prospective study included 36 patients with severe COVID-19 and 33 controls without COVID-19. EV-derived miRNAs were sequenced, and bioinformatics and differential expression analysis between groups were performed. The plasma miRNA profile of an additional cohort of patients with severe COVID-19 (n = 32) and controls (n = 12) was used to compare with our data. Survival analysis identified potential mortality predictors among the significantly differentially expressed (SDE) miRNAs in EVs.

Results
Patients with severe COVID-19 showed 50 SDE miRNAs in plasma-derived EVs. These miRNAs were associated with pathways related to inflammation and cell adhesion. Fifteen of these plasma-derived EV miRNAs were SDE in the plasma of severe cases vs controls. Two miRNAs, hsa-miR-1469 and hsa-miR-6124, were identified as strong mortality predictors with an area under the receiver operating characteristic curve of 0.938.

Conclusions
This research provides insights into the role of miRNAs within EVs in severe COVID-19 and their potential as clinical biomarkers for mortality.
Biology, ecology, host range, and management approaches for Monolepta spp. (Coleoptera: Chrysomelidae), emerging threats to crops
Authors: Ramzan Muhammad , Khashaveh Adel , Yi Chaoqun , Shan Shuang , Tang Ziyi , Liu Wentao , Khan Khalid Ali , Zhang Yongjun 
Published: June 2024

Abstract
Monolepta signata, Monolepta hieroglyphica, and Monolepta quadriguttata are highly destructive agricultural pests in East and Southeast Asia, causing considerable economic losses by damaging a variety of crops in China, including soybeans, corn, cotton, rice, and vegetables. Despite numerous studies to prevent and control their spread, these pests continue to pose a severe agricultural issue demanding attention. This review focuses on the latest research concerning the biology, hosts, and prevention of these beetles. We also explore the biotic and abiotic factors influencing the population dynamics of these pests. While insecticides are commonly employed to manage these beetles, options for suppressing adult beetles and grubs are limited. Despite ongoing regulatory efforts, these beetles remain a significant threat to several crops, including cotton and corn. Researching the pests’ interactions with predators, parasitoids, and host plants in their ecosystem can provide valuable insights into their ecological roles and potential control methods.