bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fetal Macrosomia: Demographic Analysis and Perinatal Performance in a Chinese Population
Authors: Li Dominic F. H. , Wong Vivian C. W. , Ma H. K. 
Published: August 2010

AbstractA retrospective analysis of the demographic and perinatal data of 332 macrosomic infants (≥3.8 kg) born of Chinese mothers in a teaching hospital in Hong Kong was performed. Results were compared with similar data from 334 normal weight infants (>2.5 to <3.8 kg) randomly selected in the same year. The incidence of fetal macrosomia was 5.7% of the annual deliveries. Significant maternal risk factors were increased maternal age, high pre‐pregnant weight and ponderal index, positive history of previous macrosomic babies and presence of maternal diabetes. The incidence of diabetes mellitus was 13.6%. Clinical suspicion of macrosomia before delivery was positive in only 31.0%, of cases. The uterine volume index (UVI) at term was calculated by the formula: UVI = (Fundal heightXAbdominal girth2/4π. When the UVI was >34.0 litres, the predictive value for macrosomia was 40% with a false positive rate of only 2.2%. Meconium stained liquor and caesarean section were more common. First stage of labour was comparable but second stage was significantly prolonged. Among macrosomic infants, male: female ratio was 1.7: 1. Birth trauma and neonatal jaundice were more common. Maternal diabetes is a significant contributory factor which may justify screening of the maternity population to allow early detection and treatment.
Ovarian Morphology and Histopathology in Post Pill Amenorrhea
Authors: Said Samy , Habashy Mostafa A. El , Osman Mohamed M. , Shams Ahmed T. , Madwar Amira Y. , Nayel Sayed A. 
Published: August 2010

AbstractThe morphological changes in the ovaries of 20 normal and 20 post pill amenorrhea cases were studied via laparoscopy. Ovarian biopsies were taken in some of them to study the histopathological changes. Again endometrial biopsies were taken to study the endometrial picture in cases of post pill amenorrhea and to determine the stage of the menstrual cycle in the normal controls. The ovaries were morphologically active in 13 normal control cases encountered during the late proliferative and the secretory phase. The ovaries in all cases of post pill amenorrhea, on the other hand, were resting and inactive. Ovarian biopsies confirmed the morphological findings. Regarding the endometrial biopsies, histological patterns coincided with the ovarian morphological findings in the normal controls. While the endometrium was resting in 14 and atrophic in 6 cases of post pill amenorrhea. The significance of these results were discussed.
Endometriosis in a Patient with Rudimentary Uterus and Absent Vagina: A Case Report
Authors: Buckshee Kamal , Dhond Abhey 
Published: August 2010

AbstractA 22‐year‐old female presented with primary amenorrhoea, congenital absence of vagina and rudimentary horn of the uterus. Laparoscopic examination revealed rudimentary uterus with normal tubes and small ovaries. She had 46 XX karyotype with normal intravenous pyelogram. At the time of vaginoplasty a small purple colour nodule was detected in the suburethral region, which was excised. Histopathological diagnosis of the nodule was endometriosis. Association of endometriosis with rudimentary uterus and absent vagina is a uniquefinding.
Pudendal Block: An Obstetric Procedure That Needs Critical Evaluation
Authors: Arulkumaran S. , Ingemarsson I. , Hamlett J. D. , Chua S. , Rydstrom H. , Ratnam S. S. 
Published: August 2010

AbstractThe efficacy of pudendal block anaesthesia was evaluated in three centres by obstetric staff of different seniority. In one centre a Med‐E‐Jet which drives and disperses the drug at high velocity was used. The results obtained by objective testing of pain gave a complete bilateral block in 50% of cases. In 16.7% of the cases the block was adequate only on the left side with partial or no analgesia on the opposite side; the corresponding figure for the right side was 8.9%. The remaining 24.4% of cases needed additional local infiltration and was considered as failures.The seniority of the obstetric staff or the equipment used did not improve the results. The highest success rate was achieved by staff using the method routinely. Caution is expressed in performing trial of forceps or rotational forceps delivery under pudendal block anaesthesia without objectively testing for the results achieved by the block. Considering the success obtained in unilateral blockade there is room for improving the block achieved on both sides.
Comparison of Hysterosalpingography and Laparoscopy in the Evaluation of Tubal Factor
Authors: Dhaliwal Lakhbir Kaur , Khera Kamla Rani , Gupta Indu , Gupta Amar Nath 
Published: August 2010

AbstractDiagnostic findings obtained by hysterosalpingography and laparoscopy are compared in 200 cases. In 45.5% cases the results are in agreement. False positive results by HSG are found in 21.5% of subjects and 15% were false negative findings on HSG films. HSG holds a definite place in the initial diagnostic evaluation of the tubal factor in infertile women.
Fetal Supraventricular Tachycardia Associated with a True Knot of Umbilical Cord
Authors: Chen Shin‐Zon , Teshima Hideo , Matsuoka Ryo , Mori Hiroyuki , Kigawa Tomonori 
Published: August 2010

AbstractThe association of an abnormal fetal heart rate tracing with a true knot of umbilical cord has rarely been reported. Presented is the first case report of persistent fetal supraventricular tachycardia of 230 bpm with a second degree A‐V block due to tightening of a true knot of cord. The infant was delivered successfully by emergency cesarean section without any heart decompensation. The possible pathophysiology of the monitoring findings is discussed, with a review of the literature.
Human Endometrial Adenocarcinoma Cells in vitro Response to the Administration of Steroid Hormones
Authors: Nishiya Iwao , Sato Ken , Yoshizumi Noboru , Saito Satoshi 
Published: August 2010

AbstractThis study was organized to investigate the response of cultured human endometrial adenocarcinoma cells (SNG‐M and Ishikawa) treated with Estradiol‐17β (E2), Diethylstilbestrol (DES), Progesterone (P) and Medroxyprogesterone acetate (MPA) using a flow cytometer. It could be suggested that E2 and DES (1 μg/ml) caused a decrease in the Go + Gj phase cell counts and an increase in the S and G2 + M phase cell counts, whereas both P and MPA (10 μg/ml) caused an increase in the S phase cell counts, and a decrease of the Go + G1 and G2 + M phase cell counts in SNG‐M cells.However, in Ishikawa cells no remarkable changes were observed in the cell cycle after the treatment with these hormones. In SNG‐M as well as in Ishikawa, both P and MPA (10 üg/ml) caused a remarkable decrease in the relative RNA content.
Transplantation of Human Ovarian Pseudomyxoma Peritonei to Nude Mice and Sensitivity to Anticancer Agents
Authors: Yakushiji Michiaki , Miyahara Kenichi , Nishimura Haruo , Iwanaga Shigeaki , Kato Toshi 
Published: August 2010

AbstractHuman ovarian pseudomyxoma peritonei was successfully transplanted subcutane‐ously and intraperitoneally to nude mice. The intraperitoneal tumor system showed especially close similarities to human pseudomyxoma peritonei. Serum carcinoem‐bryonic antigen levels were high both in the human tumor donor and in the majority of the nude mice recipients.Using nude mice with intraperitoneally transplanted tumors, the effects of the new anticancer agents cisplatin and adriamycin were investigated. Both singly and in combination, the two agents were effective in inhibiting tumor proliferation.The histological effect was remarkable in the mice that received treatment with both agents in combination.Serum CEA levels tended to be lower in the cases with apparent histological evidence of tumor damage.
Primary Culture of Cells Derived from Human Myometrium: Both Myometrium and Cultured Cells Stained with Desmin by the Enzyme‐Labeled Antibody Method
Authors: Otsuka Haruo , Yoshida Kohji , Kusano Shuichi , Okamura Yasushi 
Published: August 2010

AbstractTo evaluate the characteristics of myometrial cells, we studied primary cultures of cells obtained from uterine muscle.The myometrium was cut into small pieces and suspended in a trypsin solution. The primary cell culture, as a monolayer, could be passaged four times.To confirm that the cultured cells were derived from myometrium, both the myometrium and the cells were stained with desmin by the enzyme‐labeled antibody method. These were all positive. As a result, we confirmed that the cultured cells were derived from myometrium.
Delivery Following Removal and Chemotherapy of Ovarian Endodermal Sinus Tumor
Authors: Matsuoka Ryo , Kaneda Sachie , Teshima Hideo , Koike Sadanori , Mizutani Katsumi , Mori Hiroyuki , Kigawa Tomonori , Yamamoto Masashiro , Maruyama Takayoshi 
Published: August 2010

AbstractA case of delivery after treatment of an ovarian endodermal sinus tumor (stage lc) is reported. The patient was a 27‐year‐old Japanese woman who showed a rapid decrease in α‐fetoprotein after the operation and chemotherapy. Three years later, she became pregnant and bore a female baby without any malformation at full term.
Variants of 61 Cases with Gonadal Dysgenesis
Authors: Yang Yu‐Shih , Huang Jaou‐Chen , Lee Tzu‐Yao 
Published: August 2010

AbstractSixty‐one patients with gonadal dysgenesis were grouped under chromosomally incompetent ovarian failure (CIOF) and chromosomally competent ovarian failure (CCOF) according to their karyotypes. Forty‐one patients (67.2%) belong to CIOF, including: 12 cases (19.7%) with 45X; 22 cases (36.1%) with 45X/46XX; One case (1.6%) with 45X/46XX/47XXX; One case (1.6%) with 46X, i (Xq); 4 cases (6.6%) with 45X/46XY and one case (1.6%) with 46XY/47XYY. Twenty patients (32.8%) belong to CCOF including 16 cases (26.2%) with 46XX and 4 cases (6.6%) with 46XY. Various degree of phenotypic expression in different chromosomal complements were noted. Patients without X chromosome material were more likely to have complete picture of the Turner stigmata. Cases with mosaic pattern such as 45X/46XX retained some degree of fertility, prenatal genetic counselling should be advised in these cases because their progeny had higher incidence of chromosomal anomalies. As high incidence of germ cell tumors may arise from streak gonads of individuals with a Y chromosome, bilateral gonadectomy should be performed in every case as soon as possible if the diagnosis was confirmed.
Cystic Hygroma Presenting as a Case of Shoulder Dystocia in Labour
Authors: Rachagan S. P. , Yusof Khairuddin , Pathmanathan R. 
Published: August 2010

AbstractA case of a fetus with cystic hygroma presenting as shoulder dystocia in second stage of labour is presented. The use of destructive operations viz. cleidotomy and decapitation, in modern day obstetric practice and the pathology of cystic hygroma is discussed.
Hydatidiform Mole: Patient Profile and the Impact of Prophylactic Chemotherapy at the Philippine General Hospital, 1975–1983
Authors: Isidro‐Gutierrez Rosario F. , Palo‐Garcoa Fe , Blanco‐Capito Lourdes R. 
Published: August 2010

AbstractThe clinical profile of patients with hydatidiform mole admitted to the Philippine General Hospital is presented.In this study prophylactic chemotherapy for hydatidiform mole had its advantages and its risks. It reduced the development of post‐molar non‐metastatic trophoblastic disease (NMTD) and metastatic trophoblastic disease (MTD). However, it also showed that toxicity to methotrexate could be severe even with the first course. At the Philippine General Hospital the authors found it advisable to limit its use to patients who are at greater risk of developing trophoblastic sequelae.
A Comparative Study of Intrauterine Fetal Resuscitation by β‐Stimulant and O2 Inhalation
Authors: Hidaka Atsuo , Komatani Mitsuo , Ikeda Haruki , Kitanaka Takashi , Okada Kazume , Sugawa Tadashi 
Published: August 2010

AbstractA comparative study of intrauterine fetal resuscitation by administration of β‐stimulant and maternal oxygen inhalation was performed. Type II dips in labor recovered in 18% (8/44) of the cases after maternal O2 inhalation; the effectiveness of this therapy was apparent in only the 1st stage of labor.The administration of β‐stimulant (5 mg Isoxsuprine + 20 ml of 5% glucose solution) brought about recovery from fetal distress in 95% (54/57) of cases, but its effective duration was less than 30 minutes.
Tubal Pregnancy Following Laparoscopic Sterilisation
Authors: Iype Elizabeth , Nair V. Rajasekharan , Girija B. 
Published: August 2010

AbstractEctopic pregnancy following tubectomy is a well recognised entity whereas ectopic following laparoscopic sterilisation with silastic band application is not reported so far. The present paper deals with 3 cases of tubal gestation following silastic band application which occurred in a series of 22,000 cases done by the authors over a S‐year period.
Plasma Prolactin and Dehydroepiandrosterone Sulfate Levels in Polycystic Ovarian Disease
Authors: Lee Jin Yong , Yoon Byung Koo , Moon Shin Yong , Kim Jung Gu , Chang Yoon Seok 
Published: August 2010

AbstractThis study was undertaken to evaluate the prevalence rate of hyperprolactinemia (HPRL) in polycystic ovarian disease (PCOD), and to ascertain the effect of HPRL on androgen production of the adrenal cortex as well as the adrenal participation in PCOD by measuring plasma dehydroepiandrosterone sulfate (DHEAS). This study included 43 patients with PCOD and 20 normal control women. HPRL was found in 7 (16.3%) of 43 patients with PCOD. The mean plasma DHEAS level was significantly higher in patients with hyperprolactinemic PCOD than in patients with nor‐moprolactinemic PCOD. A significant positive correlation was found between plasma prolactin (PRL) and DHEAS value in the hyperprolactinemic group. [The mean plasma DHEAS concentration was significantly elevated in patients with PCOD than in normal controls. Hirsute PCOD patients had a significantly higher mean plasma level of DHEAS than non‐hirsute group. These data show a distinct profile of androgen levels in patient with PCOD and suggested that higher levels of PRL in PCOD is significantly associated with elevated DHEAS.
Immunocytochemical Study of the Placenta of a Twin Pregnancy with a Retained Dead Fetus
Authors: Ikarashi Toshihiko , Takeuchi Shoshichi , Ohnishi Yoshihisa 
Published: August 2010

AbstractA placenta of a twin pregnancy with a retained dead fetus (RDFt) was studied im‐munohistochemically by comparison with controls consisting of 9 other placentae with a retained dead fetus (RDF) and 20 placentae without an intrauterine fetal death (IUFD) (control placentae without IUFD). By immunohistochemical examination, immunoglobulins were found in villous syncytiotrophoblasts and villous endothelial cells. The positive reactions were, furthermore, diminished by pretreatment with ammonium thiocyanate by immunoelectron microscopy, so that the immunoglobulin binding to chorionic villi were regarded as one of nonspecific bindings. However, a strongly positive immunoreaction for IgG remained in the specimens from the placenta of RDFt after pretreatment with ammonium thiocyanate. The findings indicate that an immunological injury of a placenta is provoked in RDFt.
Interaction between Opioid Peptides and Monoamines in the Regulation of Gonadotropin Secretion in the Female Rat
Authors: Kawagoe Shinnosuke , Hiroi Masahiko 
Published: August 2010

AbstractAdult female rats were injected with 15 μg β‐endorphin twice, at 12: 00 and 15: 00, on the day of proestrus, with or without pretreatment with the antiserotonergic drugp‐chlorophenylalanine (PCPA, 300 mg/kg) or the anticholinergic drug atropine sulfate (150mg/kg). Administration of β‐endorphin alone caused a slight decrease in pre‐ovulatory LH release and blocked ovulation in 4 of the 10 animals. Pretreatment with PCPA, but not atropine, completely blocked the β‐endorphin action. Injection with naloxone (2 mg/kg) induced a significant increase in serum LH levels 60 minutes later in immature female rats. The naloxone‐induced LH rise was reduced by concomitant intraperitoneal administration of β‐endorphin (200 μg/kg). This β‐endorphin inhibition of naloxone action was, however, completely abolished by pretreatment with PCPA, while PCPA showed a tendency to potentiate the LH response to naloxone alone. These results suggest that serotonergic systems participate in the mechanisms whereby β‐endorphin suppresses LH secretion. In addition, the stimulatory action of naloxone on LH secretion was markedly suppressed when reserpine (2 mg/kg) or phenoxybenzamine (20 mg/kg), all antinoradrenergic drugs, were first administered, suggesting that the naloxone action to promote LH release is mediated in part via hypothalamic noradrenergic systems.
Catecholamine Concentrations of Fetal Blood and Amniotic Fluid during Labor
Authors: Mitsutani Hiroshi , Kudo Takafumi , Kishimoto Yasuo 
Published: August 2010

AbstractCatecholamine concentrations in the amniotic fluid and in the umbilical arterial plasma obtained from 52 full term deliveries were determined by radioenzymatic assay. Umbilical arterial blood pH and PO2 were also measured. There were significant correlations between umbilical arterial plasma catecholamine concentrations and pH and PO2. Significant correlations were also observed for fetal blood pH and PO2 versus amniotic fluid norepinephrine levels (pH: r = ‐ 0.340, n = 52, p<0.05 PO2: r= ‐0.351, n = 52, p<0.05) but not epinephrine levels. Moreover, there were significant positive correlations between the catecholamine concentrations in the umbilical arterial plasma and in the amniotic fluid (norepinephrine: r = 0.372, n = 52, p<0.05 epinephrine: r = 0.359, n = 52, p<0.05). These results indicate that amniotic fluid catecholamine concentrations, especially norepinephrine, reflect fetal sympathoadrenal activity which responds to acidosis and hypoxia. Amniotic fluid catecholamine levels are an indicator of fetal condition and fetal stress during labor.
Ultrasonically Guided Collection of Preovulatory Oocytes as a Feasible Alternative to Laparoscopic Procedure for Human in vitro Fertilization
Authors: Mao K. , Tam P. , Haines C. 
Published: August 2010

AbstractThe laparoscopic procedure has been widely used as the means for the collection of preovulatory oocytes for in vitro fertilization.1,2) The success of in vitro fertilization (IVF) depends largely on the accurate timing and collection of the maximal number of preovulatory oocytes in each treatment cycle. The laparoscopic procedure often achieves a high rate of oocyte recovery, usually at the first aspiration of the follicle, or during the next 3 flushings. The rate on a per follicle basis as reported in the literature varies from 60%3) in the early days of human IVF to about 80% recently.1,2,4–6) An alternative approach to collect preovulatory oocytes by percutaneous aspiration of the follicle via an ultrasonically guided needle has recently been introduced.7′8′ An overall success rate of 52–77% per follicle and 73–91% per treatment cycle was reported9,10) suggesting that the ultrasonic method is an equally efficient method of collection of the oocytes for in vitro fertilization. Both methods were employed in the IVF program offered by the Department of Obstetrics and Gynaecology in the Prince of Wales Hospital. We report here the preliminary results of oocyte collection during the first half‐year of our program. Of particular interest was a case in which a successful ultrasonic collection was made immediately after an aborted laparoscopic attempt.
The Diabetic Pregnancy: Review of Management and Resutls over Seven‐Year Period
Authors: Mittal Suneeta , Agarwal Neera , Buckshee Kamal 
Published: August 2010

AbstractA protocol for the diagnosis and management of diabetes during pregnancy is outlined Improved results have been obtained by strict antepartum surveillance, planned induction and careful monitoring during labour. A close co‐operation between obstetrician, endocrinologist and neonatologist has improved the metabolic control as well as the fetal salvage rate.Data of 109 patients with diabetes during pregnancy over a 7‐year period has been analysed. In spite of intensive monitoring 21.6% cases developed pre‐eclamptic toxaemia and 5 intrauterine fetal deaths occured. Perinatal salvage rate was better following caesarean section. The caesarean rate was 38.3% and overall perinatal mortality was 16.0%.
An Unusual Presentation of Herpes Gestationis
Authors: Lao Terence T. H. , Chang Allan M. Z. 
Published: August 2010

AbstractA Chinese woman with herpes gestationis is reported Because of the unusual features, the diagnosis was not made until the last trimester. A healthy 3.1 kg baby was delivered at term and there was no postpartum relapse. The various reported incidence of this condition may be related to mild and atypical forms which have been un‐diagnosed. The importance of immunofluorescence staining in skin biopsy is stressed, and the significance of the diagnosis is discussed with a review of the literature.
Eclamptic Pregnancies: The Influence of the Fetus and Antenatal Complications
Authors: Lao T.T.H. , Chin R.K.H. , Leung B.F.H. 
Published: August 2010

AbstractTwenty‐four eclamptic pregnancies over a 6‐year period were studied. These pregnancies were associated with a high incidence of certain antenatal complications, especially hyperemesis gravidarum, vaginal bleeding and urinary tract infection. There was also a high incidence of fetal abnormalities, including 2 cases of hydrops fetalis due to haemoglobin Bart's disease. The occurrence of these complications should alert the obstetrician to monitor these pregnancies carefully for the subsequent development of pre‐eclampsia and eclampsia.
Secondary Syphilis with Extensive Cervical Lesion
Authors: Iwasaka Tsuyoshi , Ikeda Noribumi , Sugimori Hajime 
Published: August 2010

AbstractA case of secondary syphilis which involved the uterine cervix is presented. This case was suspected to be invasive cervical carcinoma by macroscopic and colposcopic examinations, but cytologic and histologic preparations revealed syphilitic granuloma. Clinical process and serologic tests confirmed this. Computer tomography revealed swelling of para‐aortic lymphnodes as well as inguinal lymphnodes.
Seminal Plasma Fructose: Glucose Ratio as an Index of Spermatozoa Motility
Authors: Legge Michael , Hammond Erin M. , Newsome Tina J. 
Published: August 2010

AbstractSeminal plasma from 57 donors was analyzed. Of these 34 were normal, 16 abnormal and 7 had normal motility but other parameters were abnormal. A fructose: glucose ratio performed on each sample indicated a close correlation with motility. The 16 abnormal samples had a significantly lower fructose: glucose ratio than the other 2 groups tested.
Effect of Actinomycin D and Puromycin upon Basal and LH‐Induced Steroidogenesis by Hamster Follicles in Culture
Authors: Matson Phillip L. , Collins W. P. 
Published: August 2010

AbstractThe role of protein synthesis in modulating steroid production by preovulatory hamster follicles (591–740 μm) was investigated in vitro using selective inhibitors of transcription (actinomycin D; 8 μg/ml) and translation (puromycin; 80 μg/ml). The results showed:

basal oestradiol production was increased in the presence of either actinomycin D or puromycin, suggesting the existence of a protein inhibitor of oestrogen synthesis;
the initial stimulatory action of LH upon steroidogenesis is abolished by puromycin but not actinomycin D, suggesting that the synthesis of new protein is required but not new mRNA; and
the preovulatory ovarian follicle grown in a defined culture medium is a good model system to study the hormonal regulation of gene expression.