bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between Serum IGF-1 and Diabetes Among U.S. Adults
Authors: Teppala Srinivas , Shankar Anoop 
Published: July 2010

OBJECTIVE
Serum insulin-like growth factor (IGF)-1 may have a role in the maintenance of glucose homeostasis. We examined the association between serum IGF-1 and diabetes in a representative sample of U.S. adults.

RESEARCH DESIGN AND METHODS
Third National Health and Nutrition Examination Survey (NHANES III) participants aged ≥18 years (n = 5,511) were the subjects of the study. The main outcome was the presence of diabetes (n = 387).

RESULTS
Lower serum IGF-1 levels were positively associated with diabetes after adjusting for age, sex, race/ethnicity, education, smoking, alcohol intake, BMI, hypertension, glomerular filtration rate, and serum cholesterol. Compared with quartile 4 of IGF-1 (referent), the odds ratio (OR) of diabetes associated with quartile 1 was OR 2.16 (95% CI 1.24–3.76); P-trend = 0.002. However, the observed association between IGF-1 and diabetes was present only in those &lt;65 years of age (OR = 3.05; P-trend = 0.006) and disappeared in those ≥65 years of age (OR = 0.51; P-trend = 0.18); P-interaction = 0.0056.

CONCLUSIONS
Low IGF-1 levels are associated with diabetes among young subjects.
Ketone and quinone-substituted polycyclic aromatic hydrocarbons in mussel tissue, sediment, urban dust, and diesel particulate matrices
Authors: Layshock Julie A. , Wilson Glenn , Anderson Kim A. 
Published: July 2010

Abstract
Polycyclic aromatic hydrocarbons (PAHs) substituted with a ketone or quinone functionality (OPAHs) may be important environmental contaminants. The OPAHs from environmental samples have demonstrated toxicity and may be more harmful than PAHs. Knowledge gaps concerning the occurrence of OPAHs in the total environment arise from analytical difficulties, as well as limited standards and methodologies. An optimized method was developed to quantify five ketone and four quinone OPAHs from matrices ranging from biological tissue to diesel particulates. Five National Institute of Standards and Technology Standard Reference Materials (SRMs) were analyzed. This is the first report of OPAH quantitation in SRM 2977 (mussel tissue), SRM 1944 (New York/New Jersey, USA waterway sediment), SRM 1975 (diesel extract), and SRM 1650b (diesel particulate matter) and among the few to report concentrations from SRM 1649 (urban dust). Furthermore, this is one of the first reports of OPAHs in biological tissue. Σ9OPAHs were 374 ± 59 mg/kg (mussel tissue), 5.4 ± 0.5 mg/kg (sediment), 16.9 ± 1.6 mg/kg (urban dust), 33.4 ± 0.4 mg/kg (diesel extract), and 150 ± 43 mg/kg (diesel particulate matter). In all SRMs, the levels of OPAHs were similar to or exceeded levels of PAHs. Of the OPAHs tested, the most frequently occurring in the environmental matrices were 9-fluorenone, 9,10-anthraquinone, benzofluorenone, and 7,12-benz[a]anthracenequinone. Environ. Toxicol. Chem. 2010;29:2450–2460. © 2010 SETAC
Effects of prenatal stress and exercise on dentate granule cells maturation and spatial memory in adolescent mice
Authors: Bustamante Carlos , Bilbao Pamela , Contreras William , Martínez Mauricio , Mendoza Antonio , Reyes Álvaro , Pascual Rodrigo 
Published: July 2010

AbstractExposure to prenatal stress (PS) increases the risk of developing neurobehavioral disturbances later in life. Previous work has shown that exercise can exert beneficial effects on brain damage; however, it is unknown whether voluntary wheel running (VWR) can ameliorate the neurobehavioral impairments induced by PS in adolescent offspring. Pregnant CF‐1 mice were randomly assigned to control (n = 5) or stressed (n = 5) groups. Pregnant dams were subjected to restraint stress between gestational days 14 and 21 (G14–21), whereas controls remained undisturbed in their home cages. On postnatal day 21 (P21), male pups were randomly assigned to the following experimental groups: control (n = 5), stressed (n = 5), and stressed mice + daily submitted to VWR (n = 4). At P52, all groups were behaviorally evaluated in the Morris water maze. Animals were then sacrificed, and Golgi‐impregnated granule cells were morphometrically analyzed. The results indicate that PS produced significant behavioral and neuronal impairments in adolescent offspring and that VWR significantly offset these deleterious effects.
Land Use Changes and Forest Degradation in a Himalayan Watershed: Analysis and Policy Alternatives
Authors: Sharma Rakesh Kumar , Sankhayan Prem Lall , Singh Ranveer 
Published: July 2010

ABSTRACTAgriculture, horticulture, and forestry are the mainstays of the economy of the Indian state of Himachal Pradesh. The economic, technological, and institutional factors that affect land use need to be analyzed in a holistic way, especially in view of fast changing cropping patterns and declining forest density. The use of a bio-economic programming model incorporating economic and ecological factors appears to be a highly attractive tool for analysis at a micro watershed scale. The objective function of the model is to maximize the discounted gross margins from different sets of activities, namely, agricultural, livestock, and forestry over a 20 year model horizon. The model becomes non-linear by incorporating a variance and co-variance matrix of gross returns over the last five years. The model investigates the effects of alternate policy scenarios on income levels, cropping patterns, biomass use and its growth, and labour and capital requirements over next 20 years by using the General Algebraic Modelling Systems (GAMS). The biomass growth is based on a logistic growth model. Though there is a sharp increase in income by replacing traditional crops with horticultural crops, such changes are also accompanied with increased income risk. Results show a diversification strategy on the part of farmers in the study watershed rather than only maximizing profits. The biomass growth becomes sustainable if there is an increase in emigration rate, use of liquefied petroleum gas (LPG), and substitution of improved livestock. More such response through government policies can improve long term sustainability.
Social Norms, Social Capital, and the Sustainability of Small Scale Economies
Authors: Ranjan Ram 
Published: July 2010

ABSTRACTThis paper develops a conceptual model to link social norms and social capital with key socio-ecological characteristics of small scale economies in order to derive implications for the sustainability of natural resources and survival of these economies. Specifically, the extent of punishment required to deter defection is derived as a function of group size, rewards from defection, resource stock, and the risk of groundwater loss. Social norms which ordain collective participation and punishments can be endogenous, dynamic, and exhibit resilience. The implication of these possibilities on the sustainability of small scale economies is also evaluated.
Analyzing Water Institutions in the 21st Century: Guidelines for Water Researchers and Professionals
Authors: Poirier Bryan A. , de Loë Robert C. 
Published: July 2010

ABSTRACT
Institutional barriers (as opposed to technical challenges) were identified in the early 1980s as being at the root of many of the world's most challenging water resource problems. To what extent does this claim hold true today? We investigate and report on some major developments which have occurred in the field of institutional analysis over the past 25 years. An article published by Helen Ingram and colleagues in 1984 offering practical advice for water planners undertaking institutional analyses, provides the lens through which we examine changes in the field. Major developments since that article was published include an increasing sensitivity to the importance of context, a heightened awareness of the complex nature of social-ecological systems, and a growing appreciation of the dynamic nature of institutions. Much of the advice offered by Ingram and her colleagues continues to be sound, but we suggest that new insights from the past 25 years of work in this field can enhance the challenge of institutional analyses.
Effects of Renewable Energy Policies on Wind Industry Development in the US
Authors: Adelaja Adesoji , Hailu Yohannes G. , McKeown Charles H. , Tekle Ahadu T. 
Published: July 2010

ABSTRACT
To spur on renewable energy development, some US states have adopted Renewable Portfolio Standards (RPS) and related policies. Previous studies have examined the factors that lead to such policy adoption, but offer limited empirical evidence on the effects on renewable energy development. We intend to close this gap through empirical analysis. Results suggest that RPS adoption and the stringency of its inherent characteristics were dominant in spurring wind energy development, and that state wind energy potential, economic and market characteristics, energy portfolio, and political structure had significant impacts. Thus, policy and politics matter more than nature in driving wind energy deployment.
Social Movements' Pressure Strategies during Forest Disputes in Finland
Authors: Sarkki Simo , Heikkinen Hannu I. 
Published: July 2010

ABSTRACTEnvironmental non-governmental organizations (ENGOs) and rural social movements have become influential actors in natural resource governance. This article analyzes forestry dispute strategies in three cases from northern Finland, applying Actor-Network Theory (ANT), with special attention to its concept of translation, to analyze emerging multilevel stakeholder networks that include both human actors and non-human interests. Our particular focus is on the race for spokesman status on behalf of such ‘third parties’. We find that the more heterogeneous actor-networks the stakeholders build, the better opportunities they have to reach their goals. Successful strategies build environmental policy actor-networks in particular by combining different levels of human interests with different ecological arguments.
On reverse engineering of gene interaction networks using time course data with repeated measurements
Authors: Morrissey E. R. , Juárez M. A. , Denby K. J. , Burroughs N. J. 
Published: July 2010

Abstract
Motivation: Gene expression measurements are the most common data source for reverse engineering gene interaction networks. When dealing with destructive sampling in time course experiments, it is common to average any available measurements for each time point and to treat this as the actual time series data for fitting the network, neglecting the variability contained in the repeated measurements. Proceeding in such a way can affect the retrieved network topology.
Results: We propose a fully Bayesian method for reverse engineering a gene interaction network, based on time course data with repeated measurements. The observations are treated as surrogate measurements of the underlying gene expression. As these measurements often contain outliers, we use a non-Gaussian specification for dealing with measurement error. The network interactions are assumed linear and an autoregressive model is specified, augmented with indicator variables that allow inference on the topology of the network. We analyse two in silico and one in vivo experiments, the latter dealing with the circadian clock in Arabidopsis thaliana. A systematic attenuation of the estimated regulation strengths and a concomitant overestimation of their precision is demonstrated when measurement error is disregarded. Thus, a clear improvement in the inferred topology for the synthetic datasets is demonstrated when this is included. Also, the influence of outliers in the retrieved network is demonstrated when using the in vivo data.
Availability: Matlab code and data used in the article are available from http://go.warwick.ac.uk/majuarez/home/materials.
Contact: m.a.juarez@warwick.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
Multiple gene expression profile alignment for microarray time-series data clustering
Authors: Subhani Numanul , Rueda Luis , Ngom Alioune , Burden Conrad J. 
Published: July 2010

AbstractMotivation: Clustering gene expression data given in terms of time-series is a challenging problem that imposes its own particular constraints. Traditional clustering methods based on conventional similarity measures are not always suitable for clustering time-series data. A few methods have been proposed recently for clustering microarray time-series, which take the temporal dimension of the data into account. The inherent principle behind these methods is to either define a similarity measure appropriate for temporal expression data, or pre-process the data in such a way that the temporal relationships between and within the time-series are considered during the subsequent clustering phase.Results: We introduce pairwise gene expression profile alignment, which vertically shifts two profiles in such a way that the area between their corresponding curves is minimal. Based on the pairwise alignment operation, we define a new distance function that is appropriate for time-series profiles. We also introduce a new clustering method that involves multiple expression profile alignment, which generalizes pairwise alignment to a set of profiles. Extensive experiments on well-known datasets yield encouraging results of at least 80% classification accuracy.Contact: lrueda@uwindsor.caSupplementary information: Supplementary data are available at Bioinformatics online.
Evidence for Light Wavelength-Specific Photoelectrophysiological Signaling and Memory of Excess Light Episodes in Arabidopsis
Authors: Szechyńska-Hebda Magdalena , Kruk Jerzy , Górecka Magdalena , Karpińska Barbara , Karpiński Stanisław 
Published: July 2010

Abstract
Although light is essential for photosynthesis, excess light can damage the photosynthetic apparatus and deregulate other cellular processes. Thus, protective integrated regulatory responses that can dissipate excess of absorbed light energy and simultaneously optimize photosynthesis and other cellular processes under variable light conditions can prove highly adaptive. Here, we show that the local and systemic responses to an excess light episode are associated with photoelectrophysiological signaling (PEPS) as well as with changes in nonphotochemical quenching and reactive oxygen species levels. During an excess light incident, PEPS is induced by quantum redox changes in photosystem II and in its proximity and/or by changes in glutathione metabolism in chloroplasts. PEPS is transduced, at least in part, by bundle sheath cells and is light wavelength specific. PEPS systemic propagation speed and action potential are dependent on ASCORBATE PEROXIDASE2 function. Excess light episodes are physiologically memorized in leaves, and the cellular light memory effect is specific for an excess of blue (450 nm) and red (650 nm) light of similar energy. It is concluded that plants possess a complex and dynamic light training and memory system that involves quantum redox, reactive oxygen species, hormonal, and PEPS signaling and is used to optimize light acclimation and immune defenses.
Fast Diploidization in Close Mesopolyploid Relatives ofArabidopsis
Authors: Mandáková Terezie , Joly Simon , Krzywinski Martin , Mummenhoff Klaus , Lysak Martin A. 
Published: July 2010

AbstractMesopolyploid whole-genome duplication (WGD) was revealed in the ancestry of Australian Brassicaceae species with diploid-like chromosome numbers (n = 4 to 6). Multicolor comparative chromosome painting was used to reconstruct complete cytogenetic maps of the cryptic ancient polyploids. Cytogenetic analysis showed that the karyotype of the Australian Camelineae species descended from the eight ancestral chromosomes (n = 8) through allopolyploid WGD followed by the extensive reduction of chromosome number. Nuclear and maternal gene phylogenies corroborated the hybrid origin of the mesotetraploid ancestor and suggest that the hybridization event occurred ~6 to 9 million years ago. The four, five, and six fusion chromosome pairs of the analyzed close relatives of Arabidopsis thaliana represent complex mosaics of duplicated ancestral genomic blocks reshuffled by numerous chromosome rearrangements. Unequal reciprocal translocations with or without preceeding pericentric inversions and purported end-to-end chromosome fusions accompanied by inactivation and/or loss of centromeres are hypothesized to be the main pathways for the observed chromosome number reduction. Our results underline the significance of multiple rounds of WGD in the angiosperm genome evolution and demonstrate that chromosome number per se is not a reliable indicator of ploidy level.
Towards a cross‐cultural typology of trust in B2B food trade
Authors: Jan Hofstede Gert , Fritz Melanie , Canavari Maurizio , Oosterkamp Elsje , van Sprundel Gert‐jan 
Published: July 2010

PurposeThis paper aims to develop a hierarchical typology of trust elements for business‐to‐business trade among European companies in the food sector.Design/methodology/approachThe paper integrates desk research literature study and a qualitative survey of food industry companies. An extensive literature review about inter‐organizational trust lays a foundation for designing a draft typology based on previous studies, with special attention paid to the influence of culture. Fine‐tuning and validation of the typology is achieved through an exploratory field study based on 18 qualitative in‐depth interviews with key informants in five EU countries, involving practitioners from the fresh fruit and vegetable, grain, meat and olive supply chains.FindingsA detailed typology of trust is developed. Although it is highly specific to the food industry, it is designed to be neutral to culture and sector, thus allowing the identification of differences in culture when dealing with trust building elements in different sectors in the food supply chain.Research limitations/implicationsSince the buyer's perspective is adopted in this paper, further research is needed to validate the typology on the seller side. The typology developed here must also be tested in practice, for instance within a descriptive research quantitative study, aimed at quantifying the relative importance of the different trust elements.Practical implicationsThe typology stimulates the consideration of cross‐cultural or cross‐sector differences in the salience of trust attributes and its construction process confirms that reputation management is an extremely important determinant of success or failure. It can serve as a checklist for any company that is interested in improving its relationships with suppliers or buyers.Originality/valueThe paper adds to the body of knowledge about inter‐organizational trust, providing researchers with a useful tool for conducting experimental research on trust creation mechanisms.
Consumption of graham snacks in after‐school snack programs based on whole grain flour content
Authors: Sadeghi Leila , Marquart Len F. 
Published: July 2010

PurposeThe 2005Dietary Guidelines for Americansrecommend that children consume at least three daily servings of whole grains. Data from a pilot after‐school program indicated that graham snacks, containing 5 g whole wheat per serving, were consumed in the range of 73‐88 percent, similar to the refined grain counterpart. This paper aims to examine whether a full serving (16 g) of whole grain delivered in a graham snack is acceptable as tested among children participating in an after‐school snack program.Design/methodology/approachSubjects included ∼100 children (grades K‐6) participating in after‐school snack programs. Over eight weeks, children were offered graham snacks containing 5, 8, 12, and 16 g whole wheat flour per 30 g serving. Plate waste was used to measure graham snack consumption, as children placed their unfinished snacks in a receptacle and waste was measured after each session. At week nine, a subgroup of children participated in taste tests and rated each snack for liking on a nine‐point hedonic scale. Another subgroup was enrolled in group interviews to provide input about their perceptions of the products' quality and suggestions for improvement.FindingsConsumption for the 5, 8, 12, and 16 g graham snacks was 80, 76, 79, and 80 percent, respectively. The taste tests results showed no significant difference in rating of the four‐graham snacks. The focus groups indicated that overall, the products are well‐liked, particularly for texture.Originality/valueThis paper suggests that graham snacks can contribute a significant dietary source, nearly one full serving of whole grain when offered in children's natural environment through an after‐school snack program.
The influence of test situation and satisfaction with preparation on evaluation and intention to consume a new seafood product
Authors: Heide Morten , Ottar Olsen Svein , Calvo Dopico Domingo 
Published: July 2010

PurposeThe general purpose of this paper is to investigate how a newly developed burger made of seafood is perceived in different test situations. In addition, the influence of satisfaction with preparation on the evaluative outcome is explored.Design/methodology/approachData were collected from two different test situations; a home use test, and a canteen test among young Spanish consumers. Multiple measures of the constructs were used to test for construct reliability, validity and measurement invariance in two different consumption situations. The data were analysed by LISREL and ANOVA.FindingsNo differences in attitudes and intention to consume the fish burger are found for the different test situations. However, satisfaction with preparation did have a significant impact on evaluation and intention in the home situation, even though perceived preparation skill is the same.Originality/valueThis paper contributes to the existing literature on how different test locations influence product evaluation. First, methodologically, it uses multiple measures of the key dependent variables, attitude and intention, and tests for validity, reliability, and measurement invariance to approach survey context effects in different test situations. Second, theoretically, the paper also shows how the impact of satisfaction with the preparation can influence evaluation and intention to consume a new product in a home test situation.