bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does the suprapatellar nailing technique address the issue of malunion in segmental tibial fractures?
Authors: Magadum Sunil Dhondiram , Jasti Ramprasad , Mohandas Prithvi , Nandipalli Akilesh Kumar , Ragavan Mahesh Karthik 
Published: June 2024

: Segmental tibia fractures are caused by high-velocity trauma. They are often associated with soft tissue and other systemic injuries leading to higher complications rates. In this study, we aimed to analyse the clinical, functional and radiological outcome including the incidence of malunion in these fracture following suprapatellar nailing. We retrospectively analysed 55 patients from January 2016 to January 2020 who underwent suprapatellar nailing using two different nailing systems at a single tertiary care trauma centre. Periodic follow-ups were done to evaluate the union rates, the functionality of the limb and associated complications like malunion. Average time of union overall was 26 weeks with closed fractures healing at an average of 22 weeks and open fractures healing at an average of 33 weeks. The average functional score using LEFS at the end of one year was 86% with 89% of the patients having good to excellent functional outcome. We had 22 cases of the delayed union out of which only 5 cases required secondary procedures to aid in the union. Malalignment was noted in 1 case. All fractures included in this study eventually healed at the final follow up. Anterior knee pain was reported in 3.6% of the cases.: We recommend suprapatellar nailing in all segmental tibial fractures irrespective of the type of injury as it reduced the rate of malunion and anterior knee pain, without compromising on union rates and functional outcome.
Management of a Giant Cell tumors with megaprosthesis in a resource-limited setting
Authors: Augustus Megan , Ali Allan , Beharry Allan , Armorer David , Lousaing Derrick 
Published: June 2024

Giant Cell Tumors (GCTs) of bone are primary bone tumors that are benign. They are biologically aggressive and have metastatic potential after malignant transformation. There have been several cases of GCTs described in the medical literature. The management of juxta-articular GCTs in the young population is one of the greatest challenges in orthopaedic oncology. Amputations were once the standard treatment for malignant bone tumours. Advances in orthopaedic surgical techniques and bioengineering have made limb-sparing surgery a viable treatment option. Limb- salvage surgery is considered safe and is routinely undertaken for 90% of cases of bone tumors. The advances in orthopaedic surgical techniques and bioengineering of prosthesis have made this a viable option for these complex cases.Staging is performed using the Campanacci Radiographic Classification System and this is based on the radiological findings of the GCT. This staging system is used to guide the planning of the initial surgical management. Campanacci Stage III GCTs are aggressive lesions thus En bloc resection and reconstruction have been proposed as the choice of treatment. This is done with the goal of joint preservation as well as reducing the risk of recurrence. This case report highlights the challenges in the management of a Campanacci Grade III GCT of the distal femur. A mega prosthesis or endoprosthesis is a viable first-line treatment for oncological patients with significant bone and soft tissue loss. Oncological clearance was achieved then by the customized megaprosthesis was assembled and set in place. Procurement of this custom-made megaprosthesis during the COVID-19 pandemic was particularly challenging.
Monetary and Fiscal Policy Interactions and the Impact of the COVID-19 Pandemic
Authors: Burdekin Richard , Horan John , Tao Ran 
Published: June 2024

Although the onset of the pandemic pressured monetary and fiscal policy across the globe, deficit finance was aided by the large, established debt markets in countries like the United States. The expansionary efforts in emerging markets like Latin America put greater strains on their more limited capacity. Our study analyzes data from seven Latin American countries, three European countries, three Asian countries, and the United States. We utilize panel vector autoregressive (VAR) models to explore the dynamic interactions and feedback mechanisms among the policy variables, while accounting for unobserved country-specific effects. Our results demonstrate strong and significant interactions between monetary and fiscal policy around the time of the pandemic, with the primary causal effects running from fiscal to monetary policy. Additionally, our results yield evidence of countercyclical policy reactions to inflation for both monetary and fiscal policy over the pandemic period.
STUDENT PERCEPTION OF THE NEW PARADIGM INDEPENDENT CURRICULUM AT PIAUD
Authors: Windasari Indriana Warih 
Published: June 2024

This research aims to determine the perceptions of PIAUD undergraduate students regarding the new paradigm of an independent curriculum at the Early Childhood Education level. Data collection used an open questionnaire using purposive sampling techniques. The Method uses a descriptive qualitative with a case study. The location used is in the Early Childhood Islamic Education Study Program (PIAUD) Muhammadiyah Probolinggo Islamic College. The research subjects were all students of the 4th semester Islamic Early Childhood Education study program, totaling 19 people who took the Early Childhood Learning Design course. The result shows that the content and structure of the independent curriculum are substantively more simple and deeper, because it is focuses on the self-development of students, students have diverse opinions regarding the independent curriculum where in learning the Independent curriculum students are trained to express opinions with more critical, creative, and motivated in solving every learning challenge they face, and teachers are required to be more creative in determining and designing learning activities by adjusting the conditions and needs of each class.
Pengaruh Aplikasi Larutan Bawang Putih (Allium sativum) Terhadap Intensitas Serangan Hama Daun Pada Tanaman Pakcoy (Brassica rapa L)
Authors: Ramadhani Eza Galang , Rosa Helda Orbani , Pramudi Muhammad Indar 
Published: June 2024

Tanaman pakcoy (Brassica rapa L.) merupakan tanaman yang bisa ditanam pada dataran rendah atau tinggi. Namun cocok ditanam pada daerah dengan ketinggian 100-500 m diatas permukaan laut. Pestisida nabati larutan bawang putih (Allium sativum) dapat menjadi alternatif dalam menekan hama daun pada tanaman pakcoy (Brassica rapa L.). Hasil penelitian menunjukkan aplikasi larutan bawang putih pada perlakuan C (15%) dan D (20%) efektif dalam menekan serangan hama daun pada tanaman pakcoy sebesar 19,25% dan 19,50%.
Efektivitas Tanaman Bintaro (Cerbera manghas) dalam Menekan Serangan Penyakit Moler pada Bawang Merah (Allium ascalonicum L.) di Lahan Gambut
Authors: Dayatullah Dayatullah , Salamiah Salamiah , Aidawati Noor 
Published: June 2024

Bawang merah yang sejak lama dibudidayakan secara intensif oleh petani dan merupakan bagian dari kategori Bumbu Nonsubstitusi yang digunakan untuk penyedap rasa bahan makanan maupun obat tradisional Ini adalah salah satu komoditas sayuran utama. Dalam proses produksinya ditemukan berbagai gangguan, diantaranya yaitu serangan patogen penyebab penyakit moler. Penelitian ini akan mengkaji efektivitas larutan tanaman bintaro dalam menurunkan intensitas serangan penyakit Moler pada tanaman bawang merah di lahan gambut. Penelitian dilakukan di Laboratorium Fitopatologi, Fakultas Pertanian, Universitas Lambung Mangkurat, Banjarbaru dan di Desa Tegal Arum, Kecamatan Landasan Ulin, Kota Banjarbaru, Kalimantan Selatan, pada bulan Juni hingga Oktober 2022.Rancangan acak lengkap yang terdiri dari 4 perlakuan dan 5 ulangan digunakan dalam penelitian ini. Perlakuan yang diuji yaitu aplikasi buah bintaro tua, buah bintaro muda, daun bintaro ditambah 1 perlakuan kontrol. Aplikasi pestisida nabati dilakukan dengan mengocorkan larutan ke permukaan tanah tiap-tiap tanaman bawang merah sebanyak 5 ml per tanaman yang dilakukan sebanyak 7 kali dengan interval pemberian selama 1 minggu. Parameter yang diamati adalah intensitas serangan penyakit moler, jumlah umbi, berat basah umbi dan diameter umbi bawang merah. Hasil dari penelitian telah menunnjukkan bahwa masa inkubasi patogen penyebab penyakit moler adalah 14 hari. Aplikasi larutan tanaman bintaro tidak mampu menekan kejadian penyakit moler bawang merah di lahan gambut dan tidak mampu meningkatkan jumlah umbi bawang merah, akan tetapi aplikasi buah bintaro tua, mampu meningkatkan bobot basah umbi sebesar 41kg/ha dan diameter umbi sebesar 2%.
Manufacturing the activated carbon catalyst of impregnated palm core shells for biodiesel production
Authors: Rifki Ahmad , Zamhari Mustain , Purnamasari Indah 
Published: June 2024

This research aims to produce activated carbon-based heterogeneous catalyst derived from palm kernel shells impregnated with a KOH solution and to determine the effects of the concentration of the KOH solution and the time period during impregnation. The variables observed included KOH concentration and impregnation time. The impregnation process used KOH solution with the solution concentrations of 1N, 2N, 3N, 4N and 5N with impregnation process within 18 hours, 21 hours and 24 hours. AAS, FTIR and SEM were analyzed after impregnation with different concentrations and times. The results of the analysis of potassium metal showed the highest absorption occurred at a concentration of 5N within 21 hours at 25.4570%. The application of the activated carbon catalyst from palm kernel shells was conducted in making biodiesel. The process of making biodiesel was carried out with a reaction time of 120 minutes at a temperature of 60℃ with a molar ratio of 1: 12 using a catalyst of 2% (% w/w). Biodiesel yield testing referred to SNI 04-7182-2015. The analysis results obtained showed 879 kg/m3 density, 6.1 cst viscosity, 0.5 acid number, and 174℃ flash point.
KOMPARASI KONSENTRASI HIDROGEN SENSOR MQ-2 TERHADAP LUAS DAN WARNA NYALA API HASIL ELEKTROLISIS AIR
Authors: Mbulu Bernardus Crisanto Putra , Danang Murdiyanto  , Anggara Mietra 
Published: June 2024

Hidrogen merupakan bahan bakar yang banyak dikembangkan saat ini, sebagai pengganti bahan bakar fosil yang semakin menipis. Salah satu cara untuk memproduksi bahan bakar hidrogen, dapat dilakukan melalui metode elektrolisis menggunakan generator HHO dengan bahan dasar air. Penelitian ini bertujuan untuk mengetahui berapa besar produksi hidrogen dari setiap larutan elektrolit, yang dikomparasi dengan luas dan warna api yang dihasilkan. Perbandingan setiap larutan elektrolit berasal dari perbandingan mol zat terlarut dan zat pelarut () yaitu 1:12, dengan zat terlarut yang digunakan adalah NaCl, dan . Konsentrasi gas hidrogen yang dihasilkan dideteksi menggunakan sensor MQ-2, sedangkan luas dan warna api didapatkan melalui hasil video pembakaran berdurasi 20 menit yang dijadikan 100 frame foto pada setiap larutan elektrolit. Hasil dari penelitian ini didapatkan rerata produksi hidrogen untuk zat terlarut NaCl sebesar 891,0 ppm dan luas nyala api 12,64 mm2 tanpa warna biru, zat terlarut sebesar 917,33 ppm luas nyala api 16,46 mm2 dengan 40,52% warna biru, serta zat terlarut sebesar 980,67 ppm luas nyala api 17,47 mm2 dengan 76,19% warna biru
Effects of ultrasound-guided serratus plane block combined with general anesthesia on postoperative early quality of recovery and analgesia in patients undergoing transapical transcatheter aortic valve implantation surgery: a randomized controlled trial
Authors: xiao cheng , Chen Fang , Cao Lei , Yang Ming , Tan Yuting , Lin Guoyun , Yang Guiyin , Jing Sheng , Li Hong 
Published: June 2024

Abstract

Background
Compared to traditional thoracotomy, transapical transcatheter aortic valve implantation (TAVI) surgery offers reduced trauma and faster recovery, fostering the adoption of enhanced recovery after surgery (ERAS) protocols in cardiac surgery. Despite these advancements, postoperative pain management has received insufficient attention. The potential effects of multi-mode analgesia, including ultrasound-guided serratus anterior plane block (SAPB), on postoperative pain and early quality of recovery have not been widely studied, lacking comprehensive prospective evidence. Therefore, this study aims to investigate the impact of SAPB combined with general anesthesia on early recovery quality and analgesic efficacy in transapical TAVI patients.
Methods
This prospective, randomized controlled study will enroll 70 patients undergoing transapical TAVI, randomly allocated to either the SAPB group or the control group. The primary outcome, assessed using quality of recovery-40 (QOR-40) scale, focuses on the quality of recovery at 24 h and 48 h postoperatively. Secondary outcomes include the visual analog scale (VAS) pain scores at rest and during coughing at 6 h, 12 h, 24 h, and 48 h after surgery, frequency of patient-controlled analgesia (PCA) utilization at 24 h and 48 h, opioid consumption at 24 h and 48 h, time and frequency of rescue analgesia and severe pain at 24 h and 48 h, incidence of nausea and vomiting at 48 h after surgery and dosage of antiemetic drugs.
Discussion
The purpose of our study is to evaluate the effects of ultrasound-guided SAPB combined with general anesthesia on postoperative early quality of recovery and analgesia in transapical TAVI patients. The results obtained may provide valuable insight for the implementation of multi-mode analgesia and enhanced ERAS in this specific patient population.
Trial registration
China Clinical Trial Register ChiCTR2300068584. Registered on 24 February 2023.
‎An effective computational approach based on‎ ‎new multi-step collocation method for solving integral-algebraic equations‎
Authors: ‎Kamil S‎afaa Hussein , Pishbin Saeed , Darania Parviz 
Published: June 2024

Abstract

‎Some efficient numerical schemes have been used to solve integral algebraic equations (IAEs)‎. ‎In this article‎, ‎in order to find higher order method with an extensive accuracy‎, ‎new multi-step collocation method is developed for the numerical solution of IAEs‎. ‎The convergence of the proposed method is investigated and convergence orders are determined‎. ‎Two examples have been thoroughly examined to validate theoretical advancements in practical application‎. ‎Also‎, ‎we apply one-step and multi-step collocation methods to solve IAEs and compare numerical results to‎ ‎show the efficiency and high accuracy of the proposed method‎.
AMS subject classifications: 65R20, 45F15.
The INtegrating CuLtUral aspects into Diabetes Education (INCLUDE) study: protocol for a multi-level, mHealth-based intervention to prevent diabetes in Chinese immigrants
Authors: Hu Lu , Lin Nelson , Shi Yun , Cao Jiepin , Sevick Mary Ann , Li Huilin , Beasley Jeannette , Levy Natalie , Tamura Kosuke , Xu Xinyi , Jiang Yulin , Ong Iris , Yang Ximin , Bai Yujie , Su Liwen , Chan Sze Wan (Celine) , Yi Stella 
Published: June 2024

Abstract

Background: Type 2 diabetes (T2D) contributes to significant morbidity and mortality for Chinese immigrants in the United States, exacerbated by social determinants of health (SDOH) such as language barriers, limited access to healthy foods, or low health literacy.
Objective: The goal of the INtegrating CuLtUral aspects into Diabetes Education (INCLUDE) study is to test a social media-based intervention adapting the Diabetes Prevention Program (DPP) for Chinese immigrants alongside a culturally adapted community-supported agriculture (CSA) program. We report the protocol for the INCLUDE study.
Methods: INCLUDE is a three-year randomized controlled trial (n=150). Participants with prediabetes or at risk for T2D are enrolled and randomized into either the control or intervention group (n=75 each). Participants from the intervention group receive 2-3 culturally tailored, in-language DPP videos weekly for 12 weeks, and biweekly phone calls from bilingual study staff to review video content, support goal setting, and to assess and address SDOH-related barriers such as food insecurity. Intervention participants will also be given produce for 10 weeks as part of the CSA program. Weight (primary outcome), self-efficacy, diet, physical activity, and food insecurity (secondary outcomes) are measured at baseline, 3-month, and 6-month intervals. Splined linear mixed models will be used to examine group differences in longitudinal weight and other secondary outcomes. The INCLUDE study was approved by the Institutional Review Board at the NYU Grossman School of Medicine.
Trial registration: This study was registered at ClinicalTrials.gov (NCT05492916; registered 08/09/2022).
Discussion: The INCLUDE study will serve as an innovative model for culturally adapted multi-level interventions for underserved communities previously unable to access evidence-based diabetes prevention initiatives. Aligning with several national calls for multi-level interventions, the INCLUDE intervention will provide critical data that will inform how researchers and public health professionals address SDOH barriers faced by underserved populations and prevent diabetes.
Developing Normative Reference Values for Nerve Conduction Studies of Commonly Tested Nerves in the Bangladeshi Population
Authors: Alam S. K. M. , Siddik S. H. , Ferdousi Mariya , Deeba F. 
Published: June 2024

Abstract

This paper aims to establish normative reference values for nerve conduction studies specific to the Bangladeshi population. Data were collected from 258 healthy subjects, who were grouped by age and sex. We examined both motor and sensory nerves in the arms, taking into account factors such as age and sex. The findings of the current study are compared with international data published previously, highlighting significant differences. Normal reference values are presented in the form of the 95th percentile for distal latencies and the 5th percentile for amplitudes and conduction velocities. This study will assist neurophysicians in more accurately diagnosing and treating nerve conditions in Bangladesh.
The effect of paeoniflorin on the rewarding effect of METH and the associated cognitive impairment in mice
Authors: Gong Xinshuang , Yang Xiangdong , Yu Zhaoying , Lin Shujun , Zou Zhiting , Qian Liyin , Ruan Yuer , Si Zizhen , Zhou Yi , Li Yu Liu 
Published: June 2024

Abstract

Chronic exposure to methamphetamine (METH) has been suggested to cause METH use disorder and severe cognitive impairment. Paeoniflorin (PF) is a monoterpenoid glycoside with various beneficial effects, including anti-inflammatory, antioxidant and antidepressant. The current study was designed to investigate the effect of PF on the rewarding effect of METH and the associated cognitive impairment, using the animal model of conditioned place preference, new location reorganization test, new object reorganization test and Y-maze test. METH induced conditioned place preference, accompanied by increased expression of synapse-associated proteins in the ventral target areas (VTA) and nucleus accumbens (NAc). In addition, METH induced significant cognitive impairment and decreased the expression of synapse-associated proteins in the hippocampus (Hip). Administration of PF decreased the rewarding effect of METH and the expression of synapse-associated proteins in the VTA or NAc. PF was also effective to improve METH-induced cognitive impairment by upregulating the expression of synapse-associated proteins in the Hip. Therefore, PF could be a potential agent for the treatment of METH use disorder and the associated cognitive impairment.
Factors influencing operative time for mini-endoscopic combined intrarenal surgery (ECIRS) for renal stones: A multi-center cohort study
Authors: Ito Hiroki , Fukuda Tetsuo , Yamamichi Fukashi , Watanabe Takahiko , Shibata Yosuke , Tabei Tadashi , Inoue Takaaki , Matsuzaki Junichi , Kobayashi Kazuki 
Published: June 2024

Abstract

Mini-endoscopic combined intrarenal surgery (ECIRS) offers improved advantages in the treatment of renal stones. However, the factors influencing the operative time remain poorly understood. This study aimed to identify the factors that enhance treatment planning and minimize complications. Clinical data from consecutive patients who underwent mini-ECIRS for renal stones and achieved a stone-free status between 2015 and 2021 at three high-volume centers in Japan were analyzed. The final treatment outcome was evaluated by computed tomography imaging at postoperative 1 month, and a successful outcome was defined as complete stone-free or residual stone fragments ≤ 4 mm. Logistic and linear regression models were used to predict the operative duration of mini-ECIRS. An operative time of > 120 min was significantly associated with punctured pole and body mass index (BMI), and septic shock was only observed in patients with operative times of > 120 min. The multivariate model for the operative time for mini-ECIRS identified five clinical factors: punctured pole, number of stones, number of involved calyces, BMI, and preoperative nephrostomy. We believe these findings will help surgeons and patients plan suitable treatment strategies, predict the additional need for a second mini-ECIRS or retrograde intrarenal surgery alone, and avoid severe complications.
The prognosis of ex-utero intrapartum treatment for CDH: a retrospective study
Authors: Chen Lujiao , Yang Mengmeng , Chen Yuan , Zhao Baihui , Lv Changcheng , Huang Jinjin , Tan Zheng , Luo Qiong 
Published: June 2024

Abstract

Background
To explore the impact of ex-utero intrapartum treatment (EXIT) on the prognosis of fetuses antenatally diagnosed with congenital diaphragmatic hernia (CDH).
Methods
We retrospectively reviewed the clinical data of 76 patients with CDH. All patients were divided into two groups: the EXIT group and the non-EXIT group. The propensity score matching (PSM) was performed. The primary outcome was survival at 28-day after birth. The neonatal outcomes were evaluated.
Results
There were 7 fetuses who received EXIT and 7 fetuses who did not receive EXIT were matched by PSM. There were no differences in the first diagnosed gestational age of CDH, location of hernia, presence of liver hernia, the lowest o/e LHR during pregnancy, premature birth, and fetal birth weight between the two groups. All the patients in the two groups were survival beyond 28-day after birth. The duration of mechanical ventilation was shorter in the EXIT group (1 day) compared to the non-EXIT group (3 days) (P = 0.03). The surgical operation costs were lower in the EXIT group (1748.00 RMB) compared to the non-EXIT group (3325.00 RMB, P = 0.002).
Conclusions
Performing the EXIT for repairing defects and establishing an airway is a safe and effective method for treating CDH, which can reduce postoperative ventilator usage time and surgical-related costs.