bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUbLs in chromatin and genome stability
Authors: Garza Renee , Pillus Lorraine 
Published: July 2012

AbstractChromatin structure and function is based on the dynamic interactions between nucleosomes and chromatin‐associated proteins. In addition to the other post‐translational modifications considered in this review issue of Biopolymers, ubiquitin and SUMO proteins also have prominent roles in chromatin function. A specialized form of modification that involves both, referred to as SUMO‐targeted ubiquitin ligation, or STUbL [Perry, Tainer, and Boddy, Trends Biochem Sci, 2008, 33, 201–208], has significant effects on nuclear functions, ranging from gene regulation to genomic stability. Intersections between SUMO and ubiquitin in protein modification have been the subject of a recent comprehensive review [Praefcke, Hofmann, and Dohmen, Trends Biochem Sci, 2012, 37, 23–31]. Our goal here is to focus on features of enzymes with STUbL activity that have been best studied, particularly in relation to their nuclear functions in humans, flies, and yeasts. Because there are clear associations of disease and development upon loss of STUbL activities in metazoans, learning more about their function, regulation, and substrates will remain an important goal for the future. © 2012 Wiley Periodicals, Inc. Biopolymers 99: 146–154, 2013.
Three‐dimensional nanocharacterization of porous hydrogel with ion and electron beams
Authors: Al‐Abboodi Aswan , Fu Jing , Doran Pauline M. , Chan Peggy P.Y. 
Published: July 2012

AbstractPorous hydrogels provide an excellent environment for cell growth and tissue regeneration, with high permeability for oxygen, nutrients, and other water‐soluble metabolites through their high water‐content matrix. The ability to image three‐dimensional (3D) cell growth is crucial for understanding and studying various cellular activities in 3D context, particularly for designing new tissue engineering scaffold, but it is still challenging to study cell‐biomaterial interfaces with high resolution imaging. We demonstrate using focused ion beam (FIB) milling, electron imaging, and associated microanalysis techniques that novel 3D characterizations can be performed effectively on cells growing inside 3D hydrogel scaffold. With FIB‐tomography, the porous microstructures were revealed at nanometer resolution, and the cells grown inside. The results provide a unique 3D measurement of hydrogel porosity, as compared with those from porosimetry, and offer crucial insights into material factors affecting cell proliferation at specific regions within the scaffold. We also proved that high throughput correlative imaging of cell growth is viable through a silicon membrane based environment. The proposed approaches, together with the protocols developed, provide a unique platform for analysis of the microstructures of novel biomaterials, and for exploration of their interactions with the cells as well. Biotechnol. Bioeng. 2013; 110: 318–326. © 2012 Wiley Periodicals, Inc.
Sulfonyl Fluoride‐Based Prosthetic Compounds as Potential 18F Labelling Agents
Authors: Inkster James A. H. , Liu Kate , Ait‐Mohand Samia , Schaffer Paul , Guérin Brigitte , Ruth Thomas J. , Storr Tim 
Published: July 2012

AbstractNucleophilic incorporation of [18F]F− under aqueous conditions holds several advantages in radiopharmaceutical development, especially with the advent of complex biological pharmacophores. Sulfonyl fluorides can be prepared in water at room temperature, yet they have not been assayed as a potential means to 18F‐labelled biomarkers for PET chemistry. We developed a general route to prepare bifunctional 4‐formyl‐, 3‐formyl‐, 4‐maleimido‐ and 4‐oxylalkynl‐arylsulfonyl [18F]fluorides from their sulfonyl chloride analogues in 1:1 mixtures of acetonitrile, THF, or tBuOH and Cs[18F]F/Cs2CO3(aq.) in a reaction time of 15 min at room temperature. With the exception of 4‐N‐maleimide‐benzenesulfonyl fluoride (3), pyridine could be used to simplify radiotracer purification by selectively degrading the precursor without significantly affecting observed yields. The addition of pyridine at the start of [18F]fluorination (1:1:0.8 tBuOH/Cs2CO3(aq.)/pyridine) did not negatively affect yields of 3‐formyl‐2,4,6‐trimethylbenzenesulfonyl [18F]fluoride (2) and dramatically improved the yields of 4‐(prop‐2‐ynyloxy)benzenesulfonyl [18F]fluoride (4). The N‐arylsulfonyl‐4‐dimethylaminopyridinium derivative of 4 (14) can be prepared and incorporates 18F efficiently in solutions of 100 % aqueous Cs2CO3 (10 mg mL−1). As proof‐of‐principle, [18F]2 was synthesised in a preparative fashion [88(±8) % decay corrected (n=6) from start‐of‐synthesis] and used to radioactively label an oxyamino‐modified bombesin(6–14) analogue [35(±6) % decay corrected (n=4) from start‐of‐synthesis]. Total preparation time was 105–109 min from start‐of‐synthesis. Although the 18F‐peptide exhibited evidence of proteolytic defluorination and modification, our study is the first step in developing an aqueous, room temperature 18F labelling strategy.
Controllable Fabrication of TiO2 1D‐Nano/Micro Structures: Solid, Hollow, and Tube‐in‐Tube Fibers by Electrospinning and the Photocatalytic Performance
Authors: Lang Leiming , Wu Di , Xu Zheng 
Published: July 2012

AbstractThe solid, hollow, and tube‐in‐tube porous nanofiber structures of TiO2 are synthesized successfully by a simple non‐coaxial electrospinning method without using a complicated coaxial jet head, combined with adjusting the concentration of the TiO2 precursor and the pinhole diameter of the jet head and by final calcination. The formation mechanisms of different structured TiO2 fibers are discussed in detail. This method is facile and effective, and easy to scale up. Furthermore, it is a versatile method for constructing tube‐in‐tube fibers of other metal oxides such as ZrO2, SiO2, SnO2, and In2O3. The photocatalytic activity of tubular TiO2 nanofibers for the degradation of 2‐chlorophenol and 2,4‐dichlorophenol under UV or visible‐light irradiation is better than the one of commercial available TiO2 powder, rutile, and anatase TiO2 fibers.
Functionalization of Diameter‐Sorted Semiconductive SWCNTs with Photosensitizing Porphyrins: Syntheses and Photoinduced Electron Transfer
Authors: Das Sushanta K. , Sandanayaka Atula S. D. , Subbaiyan Navaneetha K. , Zandler Melvin E. , Ito Osamu , D'Souza Francis 
Published: July 2012

AbstractCovalent functionalization of diameter sorted SWCNTs with porphyrins (MP), and photochemistry to establish nanotube diameter‐dependent charge separation efficiencies are reported. The MP–SWCNT(n,m) [M=2 H or Zn, and (n,m)=(7,6) or (6,5)] nanohybrids are characterized by a variety of spectroscopic, thermogravimetric, TEM imaging techniques, and also by DFT MO calculations. The thermogravimetric, Raman and fluorescence studies reveal the presence of a moderate number of porphyrins on the SWCNT surface. The MO results suggest charge separation (CS) via the excited state of MP. Time‐resolved fluorescence studies reveal quenching of the singlet excited state of the MP with SWCNT(n,m), giving the rate constants of charge separation (kCS) in the range of (4–5)×109 s−1. Nanosecond transient absorption measurements confirm the charge‐separated radical cation and the radical anion as [MP.+–SWCNT.−] with their characteristic absorption bands in the visible and near‐IR regions. The charge separated states persist for about 70–100 ns thus giving an opportunity to utilize them to build photoelectrochemical cells, which allowed us to derive the structure–reactivity relationship between the nature of porphyrin and diameter of the employed nanotubes.
Stereoselective Preparation of (E)‐Configured 1,2‐Disubstituted Propenes from Two Aldehydes by a Two‐Carbon Stitching Strategy: Convergent Synthesis of 18,21‐Diisopropyl‐Geldanamycin Hydroquinone and Its C7 Epimer
Authors: Hampel Thomas , Neubauer Thomas , van Leeuwen Thomas , Bach Thorsten 
Published: July 2012

AbstractThe title compounds were synthesized in a longest sequence of 27 linear steps and with an overall yield of 2.9 and 3.9 %. In the course of the synthesis, two aldehydes representing carbon fragments C1C7 (Eastern fragment) and C9C21 (Western fragment) were prepared from D‐mannitol, each of which incorporated a key stereogenic center at the respective secondary methyl ether group (C6, C12) from the chiral pool material. The assembly of the two aldehydes was achieved employing α‐chloroethyl magnesium chloride as a two‐carbon building block. The carbenoid reagent was generated from α‐chloroethyl para‐tolylsulfoxide by sulfoxide–magnesium exchange and it added smoothly to the highly sensitive aldehyde of the Eastern fragment (C1C7). Upon oxidation, an α‐chloroethyl ketone was generated, which underwent a clean and high‐yielding reductive SmI2‐promoted addition to the other aldehyde fragment. Dehydration delivered the key double bond between C8 and C9 in an overall yield of 72 % over four steps. The method was shown to be generally applicable to the racemization‐free conversion of several aldehydes into the respective α‐chloroethyl ketone (11 examples, 64–95 %) and to the coupling protocol (5 examples, 66–90 %). The further course of the geldanamycin hydroquinone synthesis included a diastereoselective reduction at C7 and the implementation of the amino group at C20. Since deprotection of the two isopropyl protecting groups could not be achieved in significant yields, the structure of 18,21‐diisopropyl‐geldanamycin hydroquinone was proven by its independent synthesis from the natural product.
ChemInform Abstract: (Ni,Mg)3Si2O5(OH)4 Solid‐Solution Nanotubes Supported by Sub‐0.06 wt% Palladium as a Robust High‐Efficiency Catalyst for Suzuki—Miyaura Cross‐Coupling Reactions.
Authors: Zhu Wancheng , Yang Yan , Hu Shi , Xiang Guolei , Xu Biao , Zhuang Jing , Wang Xun 
Published: July 2012

Abstract(Ni1‐xMgx)3Si2O5 (OH)4 solid solution nanotubes with tunable compositions are hydrothermally synthesized from aqueous solutions containing appropriate amounts of Mg(NO3)2, NiCl2, Na2O·nSiO3 (n = 3.1—3.4), and NaOH (autoclave, 210 °C, 24 h).
ChemInform Abstract: Extended Structure Constructed from Organic Ligands Functionalized Sandwich‐Type Tungstoferrates.
Authors: Wang Zhi‐Shu , Zhang Zhi‐Ming , Han Xin‐Bao , Zhang Huan , Wang En‐Bo 
Published: July 2012

AbstractThe new compounds (H2enMe) 5{FeIII2FeII2 (HenMe)2 [B‐α‐FeW9O34] 2}·12H2O (I) (enMe: 1,2‐diaminopropane) and (H2enMe)3FeII (enMe)2H2{FeIII2Fe II2 (HenMe)2[B‐α‐FeW9O34 ]2}·13H2O (II) are hydrothermally synthesized from mixtures of Na9[SbW9O33], Fe3+, and enMe (150—160 °C).
ChemInform Abstract: Asymmetric Hydrosilane Reduction of Ketones Catalyzed by an Iridium Complex Bearing a Hydroxyamide‐Functionalized NHC Ligand.
Authors: Kawabata Shun , Tokura Hiromu , Chiyojima Hiroyuki , Okamoto Masaki , Sakaguchi Satoshi 
Published: July 2012

AbstractThe air‐ and moisture‐stable isoleucinol‐derived iridium carbene complex IRI in combination with AgBF4 efficiently catalyzes the stereoselective reduction of a variety of acetophenone derivatives and analogues at room temperature.
ChemInform Abstract: Synthesis of Chiral β‐ and γ‐Amino Ethers, Morpholines, and Their Homologues via Nucleophilic Ring‐Opening of Chiral Activated Aziridines and Azetidines.
Authors: Ghorai Manas K. , Shukla Dipti , Bhattacharyya Aditya 
Published: July 2012

AbstractTreatment of activated aziridines and azetidines with alcohols in the presence of Bu4NHSO4 and Cu(OTf)2 allows a simple, highly diastereo‐ and enantioselective access to β‐ and γ‐amino ethers.
ChemInform Abstract: Catalytic Oxidation of Silyl Enol Ethers to 1,2‐Diketones Employing Nitroxyl Radicals.
Authors: Hayashi Masaki , Shibuya Masatoshi , Iwabuchi Yoshiharu 
Published: July 2012

AbstractA novel method allows the synthesis of 1,2‐diketones under mild conditions through nitroxyl‐radical catalyzed oxidation of silyl enol ethers with magnesium monoperoxyphthalate as the oxidant.
ChemInform Abstract: Cyclopentadienyl—NHC Iron Complexes for Solvent‐Free Catalytic Hydrosilylation of Aldehydes and Ketones.
Authors: Bezier David , Jiang Fan , Roisnel Thierry , Sortais Jean‐Baptiste , Darcel Christophe 
Published: July 2012

AbstractIn most cases, the reaction of ketones can be performed at 50°C.
ChemInform Abstract: Fe‐Catalyzed Allylic C—C‐Bond Activation: Vinylcyclopropanes as Versatile a1,a3,d5‐Synthons in Traceless Allylic Substitutions and [3 + 2]‐Cycloadditions.
Authors: Dieskau Andre P. , Holzwarth Michael S. , Plietker Bernd 
Published: July 2012

AbstractThe low‐valent iron complex Bu4N[Fe(CO)3(NO)] catalyzes the traceless allylic substitution of vinylcyclopropanes with different nucleophiles to afford acyclic olefins with high E‐selectivity.
ChemInform Abstract: A General and Efficient Aldehyde Decarbonylation Reaction by Using a Palladium Catalyst.
Authors: Modak Atanu , Deb Arghya , Patra Tuhin , Rana Sujoy , Maity Soham , Maiti Debabrata 
Published: July 2012

AbstractA wide range of substrates are decarbonylated, without the need for an exogenous ligand for palladium as well as CO‐scavenger.
ChemInform Abstract: Efficient Preparation of β‐Branched γ,δ‐Unsaturated Esters Through Copper‐Catalyzed Allylic Alkylation of Ketene Silyl Acetal.
Authors: Li Dong , Ohmiya Hirohisa , Sawamura Masaya 
Published: July 2012

AbstractA scalable copper‐catalyzed γ‐selective and (E)‐stereospecific allylic alkylation of allylic phosphates (I) and (IV) with ketene silylacetal (II) is described.
ChemInform Abstract: Direct Allylic Amination of Allylic Alcohols with Aromatic/Aliphatic Amines Using Pd/TPPTS as an Aqueous Phase Recyclable Catalyst.
Authors: Wagh Yogesh S. , Sawant Dinesh N. , Dhake Kishor P. , Bhanage Bhalchandra M. 
Published: July 2012

AbstractTitle reaction is highly chemoselective towards monoallylation of primary amines and proceeds for a diversity of functionalized and sterically hindered aromatic and aliphatic amines.
ChemInform Abstract: Asymmetric Copper‐Catalyzed Addition of Grignard Reagents to Aryl Alkyl Ketones.
Authors: Madduri Ashoka V. R. , Harutyunyan Syuzanna R. , Minnaard Adriaan J. 
Published: July 2012

AbstractThe first enantioselective title reaction to the aryl alkyl ketones is presented.
ChemInform Abstract: Synthesis of β‐Hydroxy and β‐Amino Ketones from Allylic Alcohols Catalyzed by Ru(η5‐C5Ph5)(CO)2Cl.
Authors: Bartoszewicz Agnieszka , Jezowska Martina M. , Laymand Kevin , Moebus Juri , Martin‐Matute Belen 
Published: July 2012

AbstractA ruthenium‐catalyzed tandem isomerization/C—C bond formation reaction is applied to the synthesis of the title compounds, respectively.
ChemInform Abstract: Stereoselective Synthesis of α,β‐Unsaturated Carboxylic Acids from Alkynes Using the Fe(CO)5/t‐BuOK/AcOH/CH2Cl2 Reagent System.
Authors: Beesu Mallesh , Periasamy Mariappan 
Published: July 2012

AbstractA simple, one‐pot procedure for the synthesis of (E)‐2,3‐disubstituted acrylic acids from alkynes proceeds via formation of Fe(CO)4‐ intermediates.
ChemInform Abstract: Copper‐Mediated Sequential Cyanation of Aryl C—B and Arene C—H Bonds Using Ammonium Iodide and DMF.
Authors: Kim Jinho , Choi Jiho , Shin Kwangmin , Chang Sukbok 
Published: July 2012

AbstractBoronic acids, boronate esters, borate salts, and electron‐rich arenes are efficiently cyanated with high functional group tolerance using a new oxidative procedure with NH4I (N source) and DMF (C source).
ChemInform Abstract: CeO2‐Catalyzed One‐Pot Selective Synthesis of Esters from Nitriles and Alcohols.
Authors: Tamura Masazumi , Tonomura Takuya , Shimizu Ken‐ichi , Satsuma Atsushi 
Published: July 2012

AbstractCeric oxide is a reusable catalyst for the preparation of esters (III) by solvent‐free reaction of nitriles (I) with alcohols (II).
ChemInform Abstract: Copper‐Catalyzed Direct Thiolation of Pentafluorobenzene with Diaryl Disulfides or Aryl Thiols by C—H and C—F Bond Activation.
Authors: Yu Chuanming , Zhang Cuiling , Shi Xiangjun 
Published: July 2012

AbstractUnder optimized conditions, bisulfides (III) are formed by activation of the C—H and the C—F bond of fluorobenzene (I).
ChemInform Abstract: Unification of Anion Relay Chemistry with the Takeda and Hiyama Cross‐Coupling Reactions: Identification of an Effective Silicon‐Based Transfer Agent.
Authors: Smith Amos B. III , Hoye Adam T. , Martinez‐Solorio Dionicio , Kim Won‐Suk , Tong Rongbiao 
Published: July 2012

AbstractAn efficient method for the cross coupling reaction of aryl‐ and alkenyllithium reagents with aryl and alkenyl halides is presented.
ChemInform Abstract: One‐Pot Three‐Component Synthesis of β‐Acetamido Carbonyl Compounds Catalyzed by Heteropoly Acids.
Authors: Javid Ali , Heravi Majid M. , Bamoharram Fatemeh F. 
Published: July 2012

Abstractβ‐Acetamido carbonyl compounds (IV) are obtained via a new Mannich‐type three‐component reaction of various aromatic aldehydes, acetamide, and dimedone.
ChemInform Abstract: Design of Main‐Chain Polymer of Chiral Imidazolidinone for Asymmetric Organocatalysis Application.
Authors: Haraguchi Naoki , Kiyono Hitomi , Takemura Yu , Itsuno Shinichi 
Published: July 2012

AbstractChiral imidazolinones are incorporated into the main‐chain of the polymer by ionic bonding.
ChemInform Abstract: Asymmetric Michael Addition Reactions Between 3‐Substituted Benzofuran‐2(3H)‐ones and 1,1‐Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups.
Authors: Li Xin , Zhang Yue‐Yan , Xue Xiao‐Song , Jin Jia‐Lu , Tan Bo‐Xuan , Liu Cong , Dong Nan , Cheng Jin‐Pei 
Published: July 2012

AbstractA bifunctional Cinchona alkaloid‐based organocatalyst efficiently catalyzes the asymmetric Michael addition of 3‐substituted benzofuranones (I) and (IV) with bis(phenylsulfonyl)ethylene (II).
ChemInform Abstract: Reaction of 2‐Aminobenzamides with Indoline‐2,3‐dione in an Ionic Liquid in the Presence and Absence of Iodine.
Authors: Sheng Jie , Yang Ke , Zhang Mei‐Mei , Wang Xiang‐Shan 
Published: July 2012

AbstractIodine is assumed to act as mild Lewis acid catalyst to facilitate the dehydration of α‐hydroxyamine derivatives (III).
ChemInform Abstract: Diastereo‐ and Enantioselective [3 + 2] Cycloaddition Reaction of Morita—Baylis—Hillman Carbonates of Isatins with N‐Phenylmaleimide Catalyzed by Me‐DuPhos.
Authors: Wang Yan , Liu Li , Zhang Tao , Zhong Neng‐Jun , Wang Dong , Chen Yong‐Jun 
Published: July 2012

AbstractThe reaction allows an efficient access to optically active spirocyclic oxindoles of biological interest.
ChemInform Abstract: Synthesis of Terphenyl Benzimidazoles as Tubulin Polymerization Inhibitors.
Authors: Kamal Ahmed , Reddy M. Kashi , Shaik Thokhir B. , Rajender Rajender , Srikanth Y. V. V. , Reddy V. Santhosh , Kumar G. Bharath , Kalivendi Shasi V. 
Published: July 2012

AbstractA library of a new class of benzimidazoles (VII) (30 examples) is designed, synthesized and evaluated for their anticancer activity.
ChemInform Abstract: A Novel Three‐Component [3 + 2] Cycloannulation Process for the Rapid and Highly Stereoselective Synthesis of Pyrrolobenzoxazoles.
Authors: Boomhoff Michael , Schneider Christoph 
Published: July 2012

AbstractFour new σ‐bonds and two chiral centers are formed by the title reaction of to give pyrrolobenzoxazoles as single diastereomers.
ChemInform Abstract: Synthesis of 1,5‐Disubstituted 1H‐Tetrazole Derivatives via a Three‐Component Reaction of Carbodiimides, Isocyanides, and Trimethylsilyl Azide.
Authors: Kazemizadeh Ali Reza , Hajaliakbari Nasrin , Hajian Roghayeh , Shajari Nahid , Ramazani Ali 
Published: July 2012

AbstractThe mild and efficient synthesis of the title compounds (III) is presented including an easy work‐up and without the need of any purification.
ChemInform Abstract: Enantioselective Synthesis of 3,4‐Dihydropyran Derivatives via Organocatalytic Michael Reaction of α,β‐Unsaturated Enones.
Authors: Liu Yangbin , Liu Xiaohua , Wang Min , He Peng , Lin Lili , Feng Xiaoming 
Published: July 2012

AbstractThe catalyst system efficiently promotes the asymmetric addition of enones to cyclic 1,3‐diones to form chromenone derivatives like (III) and (VI) and the anticoagulant warfarin (VIII).
ChemInform Abstract: One‐Pot Synthesis of Thiazolo[3,2‐α]pyridine Derivatives Catalyzed by Ionic Liquids.
Authors: Chen Hai‐Liang , Guo Hong‐Yun 
Published: July 2012

AbstractThree‐component reaction between methyl thioglycolate (I), aromatic aldehydes (III), and malononitrile or ethyl cyanoacetate (II) catalyzed by hydroxyethylammonium acetate provides a novel access towards title thiazolopyridines (IV).
ChemInform Abstract: Light‐Induced Free Radical Oxidation of 2‐Oxo‐1,2,3,4‐tetrahydropyrimidines.
Authors: Memarian Hamid Reza , Hejazi Leila , Farhadi Asadallah 
Published: July 2012

AbstractThe dehydrogenation of title tetrahydropyrimidinones (I) and (III) proceeds smoothly by UV‐irradiation in the presence of benzoyl peroxide under argon atmosphere.
ChemInform Abstract: Hydroxyl May Not Be Indispensable for Raltegravir: Design, Synthesis and SAR Studies of Raltegravir Derivatives as HIV‐1 Inhibitors.
Authors: Wang Ziwen , Wang Mingxiao , Yao Xue , Li Yue , Qiao Wentao , Geng Yunqi , Liu Yuxiu , Wang Qingmin 
Published: July 2012

AbstractA variety of raltegravir derivatives such as (I) and (II) is synthesized and systematically evaluated for their anti‐HIV activity.
ChemInform Abstract: Design and Synthesis of New 1,3‐Benzdiazinan‐4‐one Derivatives as Selective Cyclooxygenase (COX‐2) Inhibitors.
Authors: Zarghi Afshin , Zebardast Tannaz , Hajighasemali Fatemeh , Alipoor Eskandar , Daraie Bahram , Hedayati Mehdi 
Published: July 2012

AbstractTwo series of regioisomeric title compounds of type (V) and (IX) are prepared and tested for their cyclooxygenase‐2 (COX‐2) inhibitory activities.
ChemInform Abstract: Efficient Synthesis of Mono‐ and Disubstituted 2,3‐Dihydroquinazolin‐4(1H)‐ones Using Copper Benzenesulfonate as a Reusable Catalyst in Aqueous Solution.
Authors: Wang Min , Zhang Ting T. , Liang Yan , Gao Jing J. 
Published: July 2012

AbstractThe Cu(II)‐catalyzed one‐pot, three‐component cyclocondensation of isatoic anhydride, aromatic aldehydes, and ammonium salt or primary amines affords dihydroquinazolinone derivatives in excellent yields.
ChemInform Abstract: Regioselective Reduction of 3‐Substituted N‐Acylpyrazinium Salts Toward the Synthesis of 1,2‐Dihydropyrazines.
Authors: Williams Alfred L. , Hilaire Valentine R. St. , Lee Tina 
Published: July 2012

AbstractIn the presence of Bu3SnH, N‐acylpyrazinium salts bearing an electron‐donating group in position 3 undergo regioselective reduction yielding 1,2‐dihydropyrazines.
ChemInform Abstract: PhI(OAc)2‐Mediated One‐Pot Synthesis of Benzoxazinones from Anthranilic Acids and Aromatic Aldehydes.
Authors: Xie Yuanyuan , Wang Suping 
Published: July 2012

AbstractA completely new route to benzoxazinones (III) is developed, involving Schiff base formation from anthranilic acids (I) and aromatic aldehydes, followed by oxidative cyclization reaction.
ChemInform Abstract: Synthesis, Characterization and Potential Anticonvulsants Activity of Various 3‐(Substituted)‐benzylidene‐7‐chloro‐5‐phenyl‐1,3‐dihydro‐benzo[e] [1,4]diazepin‐2‐one.
Authors: Ahmad Bahar , Rashid Mohd , Husain Asif , Mishra Ravinesh 
Published: July 2012

AbstractNovel 3‐benzylidene‐benzodiazepines (III) are synthesized and tested for their anticonvulsant potency.
ChemInform Abstract: Concise Synthesis of 2‐Benzazepine Derivatives and Their Biological Activity.
Authors: So Masahiro , Kotake Tomoko , Matsuura Kenji , Inui Makoto , Kamimura Akio 
Published: July 2012

AbstractThe derivatives (VIb) and (R)‐ and (S)‐(IXa) are found to stimulate wound healing.
ChemInform Abstract: Convenient Synthesis of α‐Perfluoroaryl and α‐Perfluorohetaryl Substituted α‐Aminomethanephosphonates.
Authors: Goulioukina Nataliya S. , Mitrofanov Alexander Y. , Beletskaya Irina P. 
Published: July 2012

AbstractThe potassium salt of phosphoglycine Schiff base (III) is a suitable nucleophile for the direct preparation of the phosphonic analogues of α‐C‐perfluoro(het)aryl‐substituted glycine esters via SNAr reaction with perfluoro(het)arenes (IV), providing title compounds (V) under mild conditions in satisfactory yields and high regioselectivity.