bluuebunny/crossref_metadata_2025_split huggingface dataset:
The routine use of a flumazenil infusion following percutaneous endoscopic gastrostomy placement to reduce early post-procedure mortality
Authors: Bosanko NC , Barrett D , Emm C , Lycett W , O’Toole S , Evans K , Hearing SD 
Published: June 2010

Objectives: Percutaneous endoscopic gastrostomy (PEG) insertion offers secure enteral nutrition, but there is a significant mortality associated with the procedure. We reviewed our sedation practice and the effect of yearly protocol changes to establish if the routine reversal of midazolam with a flumazenil infusion improved mortality. Methods: Since 2003 yearly protocol changes have been introduced, including pre-assessment and sedation reversal. We retrospectively audited one-week and one-month mortality and aspiration rates. Results: The average one-week mortality rate was 9.2%. The pooled death rates within the first week for patients prior to routine sedation reversal (n=522) was 10.7% and for patients who received routine reversal (n=144) was 5.4% (p=0.087). Within the first month, death rates were 26.3% prior to reversal and 21.4% in the sedation reversal group (p=0.30). Conclusions: The routine use of flumazenil infusion in appropriate patients is safe. Flumazenil infusion may have a role to play in selected patients at highest risk of aspiration. A prospective, randomised study is warranted.
pH‐Activated Near‐Infrared Fluorescence Nanoprobe Imaging Tumors by Sensing the Acidic Microenvironment
Authors: Li Cong , Xia Jinsong , Wei Xunbin , Yan Huihui , Si Zhan , Ju Shenghong 
Published: June 2010

AbstractImaging tumors in their early stages is crucial to increase the surviving rate of cancer patients. Currently most fluorescence probes visualize the neoplasia by targeting the tumor‐associated receptor over‐expressed on the cancer cell membrane. However, the expression level of these receptors in vivo is hard to predict, which limits their clinical translation. Furthermore, the signal output of these receptor‐targeting probes usually stays at a high level, which leads to a strong background signal in normal tissue due to non‐specific binding. In contrast to receptors, characteristics of the tumor microenvironment – such as acidosis – are pervasive in almost all solid tumors and can be easily accessed. In this work, a novel biodegradable nanoprobe InNP1 that demonstrates pH‐activated near‐infrared (NIR) fluorescence in both human glioblastoma U87MG cancer cells in vitro and the subcutaneous U87MG tumor xenografts in vivo is developed. Bio‐distribution, in vivo optical imaging, and autoradiography studies demonstrate that the pH‐activated NIR fluorescence is the dominant factor responsible for the high tumor/normal tissue (T/N) ratio of InNP1 in vivo. Overall, the work provides a nanoprobe prototype to visualize the solid tumor in vivo with high sensitivity and minimal systemic toxicity by sensing the tumor acidic microenvironment.
Construction and Characterization of Porous SiO2/Hydrogel Hybrids as Optical Biosensors for Rapid Detection of Bacteria
Authors: Massad‐Ivanir Naama , Shtenberg Giorgi , Zeidman Tal , Segal Ester 
Published: June 2010

AbstractThe use of a new class of hybrid nanomaterials as label‐free optical biosensors for bacteria detection (E. coli K12 as a model system) is demonstrated. The hybrids combine a porous SiO2 (PSiO2) optical nanostructure (a Fabry–Pérot thin film) used as the optical transducer element and a hydrogel. The hydrogel, polyacrylamide, is synthesized in situ within the nanostructure inorganic host and conjugated with specific monoclonal antibodies (IgGs) to provide the active component of the biosensor. The immobilization of the IgGs onto the hydrogel via a biotin‐streptavidin system is confirmed by fluorescent labeling experiments and reflective interferometric Fourier transform spectroscopy (RIFTS). Additionally, the immobilized IgGs maintain their immunoactivity and specificity when attached to the sensor surface. Exposure of these modified‐hybrids to the target bacteria results in “direct cell capture” onto the biosensor surface. These specific binding events induce predictable changes in the thin‐film optical interference spectrum of the hybrid. Preliminary studies demonstrate the applicability of these biosensors for the detection of low bacterial concentrations in the range of 103–105 cell mL−1 within minutes.
Cardiac tamponade or normal respiratory variation? An illustrative case of septal ablation for obstructive hypertrophic cardiomyopathy
Authors: Schwartzenberg Shmuel , Sorajja Paul 
Published: June 2010

AbstractCardiac tamponade can be a lethal complication in the cardiac catheterization laboratory. Patients with obstructive hypertrophic cardiomyopathy are particularly vulnerable to the hemodynamic effects of tamponade because of their heightened sensitivity to ventricular load in the generation of forward stroke volume. Cardiac tamponade should be distinguished from the normal effects of respiration on dynamic outflow tract obstruction in these patients. This recognition not only ensures an accurate hemodynamic diagnosis, but it also will expedite timely therapy for patients in need. © 2010 Wiley‐Liss, Inc.
A novel 14F endograft for abdominal aortic aneurysm: First in man
Authors: Laborde Jean Claude , Kipshidze Nickolas , Ruiz Carlos E. 
Published: June 2010

AbstractObjective: This study evaluated the feasibility of percutaneous endovascular treatment of infra‐renal abdominal aortic aneurysm (AAA) using the novel low profile modular Tripelay system (Tripelay, France). Background: Endovascular aortic aneurysm treatment (EVAR) has become more widely used as early mortality has been significantly reduced. Also, percutaneous access has become possible with the introduction of vascular closure devices and with the initial reduction in size of delivery catheters. However, percutaneous access is not commonly used and anatomical considerations, such as access vessel size and tortuousities, preclude a number of patients from being efficiently treated with EVAR. Methods: The novel Tripelay system enables two semicircular preshaped self‐expandable stentgrafts to be positioned side by side on the aneurysm neck extending into the iliac arteries. Each stentgraft being smaller than the target vessel diameter, the delivery catheter is reduced in size (14F) and accommodates with smaller and more tortuous access vessels than conventional devices. This device was used to treat a 57‐year‐old male patient with significant comorbidities (previous coronary artery bypass grafting (CABG) and abdominal surgeries, smoking, hypertension, obesity, hyperlipidemia). Percutaneous access was made on both femoral arteries. The device was inserted, positioned, and deployed as planned. Iliac extensions were used bilaterally. Results: The EVAR procedure was performed successfully, and the patient was discharged on day 6. Follow‐up computed tomography scans at 1, 6, and 12 months revealed perfect exclusion of the aneurysm sac, patent stentgraft, and vessels, and no prosthesis migration, endoleaks or stent fracture were observed. The patient remained asymptomatic and reported no adverse events during that period. Conclusion: The Tripelay system seemed as an effective and user friendly tool for treatment of AAAs. Of course, this procedure still needs further clinical evaluation with more cases and longer follow‐up to confirm long‐term efficacy and safety of this device. © 2010 Wiley‐Liss, Inc.
Use of a self‐expanding super‐elastic all‐metal endoprosthesis; To treat degenerated SVG lesions: The SESAME first in man trial
Authors: Abizaid Alexander , Weiner Bonnie , Bailey Steven R. , Londero Hugo 
Published: June 2010

AbstractWe prospectively evaluated a novel nano‐synthesized, membrane‐covered self‐expanding super‐elastic all‐metal endoprosthesis stent (SESAME Stent™) in patients undergoing percutaneous intervention (PCI) of degenerated saphenous vein graft (SVG) lesions. Methods: SESAME investigators prospectively enrolled 20 patients/21 lesions at 2 outside United States (OUS) centers, between February 2005 and August 2005. Patients underwent elective intervention of symptomatic SVG lesions with ≥50% stenosis. PCI was performed without embolic protection devices. The primary end point was technical and procedural success. Secondary end points included major adverse cardiac events (MACE) at 30 days and 9 months. Results: Twenty patients (twenty‐one SVG lesions) received SESAME stents. The acute success was 100%. No procedural or in hospital complications occurred. One patient underwent a planned staged PCI at 28 days in a separate SVG. Follow‐up was present in 20 patients at 30 days, with clinical (n = 19) and angiographic evaluation (18 patients/19 lesions) at 9 months. No MACE events occurred at 30 days. At 9 months, 3 patients underwent repeat PCI. One TLR (restenosis at the overlap of two stents) and two nonindex lesion TVR for a MACE rate of 14% at 9 months. Conclusions: This study demonstrated the ABPS SESAME Stent™ has excellent acute success, low 30 day MACE rates and 9 month patency of the SESAME is similar to balloon expandable stents without embolic protection.© 2010 Wiley‐Liss, Inc.
Selective drug‐eluting stent implantation for high‐risk patients with acute ST‐elevation myocardial infarction: Rationale and safety
Authors: Prasad Sandhir B. , David Thomas , Malaiapan Yuvaraj , Cameron James D. , Meredith Ian T. 
Published: June 2010

AbstractBackground: A selective policy of drug‐eluting stent (DES) implantation in ST‐elevation myocardial infarction (STEMI) patients at high risk of restenosis may maximize the benefit from restenosis reduction and minimize risk from late stent thrombosis (LaST). Objectives: We sought to prospectively determine the safety of selective DES implantation for long lesions (>20 mm), small vessels (<2.5 mm) and diabetic patients in patients with STEMI using a prospective single‐center registry. Methods: A total of 252 patients who underwent primary PCI between January 2005 and December 2006 were included: 126 consecutive patients receiving DES were compared with 126 age‐, sex‐, and vessel‐matched controls with STEMI who received bare‐metal stents. Composite major adverse cardiovascular events (MACE) (death, AMI, and target vessel revascularization) were used as the primary outcome measure. Results: Baseline clinical and angiographic characteristics and outcomes were similar between groups except for the prespecified diabetes, lesion length, and maximum stent diameter. Long‐term outcomes at a median follow up of 34 ± 6 months showed significant reductions in reinfarction (2% vs. 11%, P = 0.03), target vessel revascularization (TVR) (10% vs. 24%, P = 0.02), and composite MACE (18% vs. 31%, P = 0.03) with DES, with no excess of death (9% vs. 7%, P = NS) or LaST (2% vs. 1%, P = NS). In a Cox multivariate model, clopidogrel cessation at long‐term follow‐up was the most powerful predictor of hierarchical MACE (HR: 5.165; 95%CI: 2.019–13.150, P = 0.001). Conclusions: Selective DES implantation in patients with high‐risk STEMI appears safe, and exposes fewer patients to the risk of LaST. A randomized comparison of selective versus routine DES use in patients with STEMI should be considered. © 2010 Wiley‐Liss, Inc.
ChemInform Abstract: Comparison of the Manganese Cluster in Oxygen‐Evolving Photosystem II with Distorted Cubane Manganese Compounds Through X‐Ray Absorption Spectroscopy.
Authors: Cinco Roehl M. , Rompel Annette , Visser Hendrik , Aromi Guillem , Christou George , Sauer Kenneth , Klein Melvin P. , Yachandra Vittal K. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: GaN Derived from Carbodiimide‐Based Polymer Precursors.
Authors: Rodewald Dieter , Bill Joachim , Beck Ulrich , Puchinger Manfred , Wagner Thomas , Greiner Axel , Aldinger Fritz 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: trans‐2,5‐Dialkylpyrrolidinyl‐Containing Phosphinamines. Synthetic and Mechanistic Studies in Pd‐Catalyzed Asymmetric Allylic Alkylation.
Authors: Cahill John P. , Cunneen Deirdre , Guiry Patrick J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transfer of Chirality in Radical Cyclizations. Cyclization of o‐Haloacrylanilides to Oxindoles with Transfer of Axial Chirality to a Newly Formed Stereocenter.
Authors: Curran Dennis P. , Liu Weidong , Chen Christine Hiu‐Tung 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Alkylation of Aromatic Aldehydes with Diethylzinc Catalyzed by a Fluorous BINOL—Ti Complex in an Organic and Fluorous Biphase System.
Authors: Nakamura Yutaka , Takeuchi Seiji , Ohgo Yoshiaki , Curran Dennis P. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dipolar Cycloadditions. Part 115. Cycloadditions of Thiocarbonyl Ylides with N‐Sulfinylamines.
Authors: Huisgen Rolf , Mloston Grzegorz , Polborn Kurt 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Amphiphilic Cleavage of γ‐Iodo Carbonyl Substrates with Aluminum Tris(2,6‐diphenylphenoxide)/t‐BuLi System.
Authors: Kondo Yuichiro , Kon‐i Kana , Ooi Takashi , Maruoka Keiji 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ring Closing Metathesis of Phenyl‐Substituted Dienes.
Authors: Bujard M. , Briot A. , Gouverneur V. , Mioskowski C. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phosphorylated Azoles. Part 2. Phosphorylation of 1‐Alkylimidazoles and 1‐Alkylbenzimidazoles with Phosphorus(III) Halides in the Presence of Bases.
Authors: Tolmachev Andrej A. , Yurchenko Aleksandr A. , Merculov Anatolij S. , Semenova Marina G. , Zarudnitskii Evgenij V. , Ivanov Vladimir V. , Pinchuk Aleksandr M. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Stereospecific, Intermolecular Biaryl‐Coupling Approach to Korupensamine A en Route to the Michellamines.
Authors: Lipshutz Bruce H. , Keith John M. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Chemoselective α‐Diazo Carbonyl Insertion Reactions into N—H and S—H Bonds Catalyzed by [RuCl(η5‐C5H5) (PPh3)2].
Authors: Del Zotto Alessandro , Baratta Walter , Rigo Pierluigi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of gem‐Dinitro Compounds with a Three‐Membered Cycle.
Authors: Moiseev I. K. , Mratkhuzina T. A. , Balenkova E. S. , Makarova N. V. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Effect of Lewis Acids on the Pinacol Homocoupling Reaction of Aldehydes Promoted by Samarium Diiodide.
Authors: Annunziata Rita , Benaglia Maurizio , Cinquini Mauro , Raimondi Laura 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of β‐Sultams Using Chiral Tricarbonyl(η6‐arene)chromium(0) Complexes.
Authors: Baldoli Clara , Del Buttero Paola , Perdicchia Dario , Pilati Tullio 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2,2‐Dimethyl‐2,3‐dihydrofuran, a New Substrate for Intermolecular Asymmetric Heck Reactions.
Authors: Hennessy Alan J. , Malone Yvonne M. , Guiry Patrick J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Cylindrical Cavity with Two Different Hydrogen‐Binding Boundaries: The Calix[4]arene Skeleton Screwed onto the meso‐Positions of the Calix[4]pyrrole.
Authors: Bonomo Lucia , Solari Euro , Toraman Guelsen , Scopelliti Rosario , Latronico Mario , Floriani Carlo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unambiguous Characterization of Dienylimines as Intermediates in Fischer Indolization of o‐Substituted N‐Trifluoroacetyl Enehydrazines.
Authors: Miyata Okiko , Kimura Yasuo , Naito Takeaki 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metronidazole Derivatives with Intramolecular Equivalents of Reduction.
Authors: Goerlitzer K. , Klanck S. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Cost‐Efficient Synthesis of Simvastatin via High‐Conversion Methylation of an Alkoxide Ester Enolate.
Authors: Thaper Rajesh K. , Kumar Yatendra , Kumar S. M. Dileep , Misra Satyananda , Khanna Jag Mohan 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Purines and Azapurines.
Authors: Shishoo C. J. , Jain K. S. , Jain S. R. , Shirsath V. S. , Ravikumar T. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactions of the Carbanions of Substituted 2‐Cyanopropionamides and 2‐Cyanothiopropionamides: O‐ and S‐Methylation with Methyl Trifluoromethanesulfonate.
Authors: Gololobov Yuri G. , Kuzminseva Irina , Khroustalyov Viktor , Petrovskii Pavel V. , Griffiths D. Vaughan 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: X‐Ray Study of the Spinel LiMn2O4 at Low Temperatures.
Authors: Rousse G. , Masquelier C. , Rodriguez‐Carvajal J. , Elkaim E. , Lauriat J.‐P. , Martinez J. L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 89Y MAS NMR in Red Phosphor, Eu‐Doped Y2O2S. Assignment of Peaks Shifted by Paramagnetic Eu3+, Spin Lattice Relaxation Time, and Eu Distribution.
Authors: Harazono Toshie , Adachi Ryuji , Kijima Naoto , Watanabe Tokuko 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.