bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soft skills development in the process of teaching “Tourism” students a foreign language
Authors: Bortnikova T. G. , Dolzhenkova M. I. 
Published: May 2024

Importance. Soft skills formation as a part of teaching a foreign language to students of the educational direction “Tourism” contributes to communication skills, empathy, creativity and flexibility of thinking, which are necessary in their future professional activities. The purpose of this study is: 1) analysis of the goals of teaching a foreign language and their correlation with the process of developing hard and soft skills; 2) conducting an empirical study to test the possibility of developing soft skills when teaching a foreign language; 3) identification of significant issues related to the interpretation and use of various cultural codes in communication activities. Attention is focused on the fact that behavioral stereotypes can be variably interpreted depending on which linguistic and cultural communities the communicants belong to. It is emphasized that familiarity with the cultural codes of the studied language and trainings on the development of soft skills can significantly improve the decoding and communicative abilities of students in the process of working with the material for creating advertising texts of tourist destinations and excursion programmes.Materials and Methods. The experiment is carried out at Derzhavin Tambov State University with the aim of compiling on its basis fragments of research based on the relevance of the topic, a review of scientific literature (definitions and experimental data published in this field of knowledge), selection of bibliography and results’ analysis of its experimental verification. The experiment is based on the use of foreign languages teaching methods. The criteria for selecting educational material are texts related to the popularization and advertising of tourist destinations and step-by-step training is aimed at developing soft skills within the framework of game-based educational activities.Results and Discussion. Step-by-step training has shown its success in solving a number of assigned tasks. Students become more flexible in the communication process, showing the correct reactions in accordance with the situation and the target audience, the skills of formulating and implementing communication goals are developed (in such aspects as informational, informative, normative), choosing and using established constructs within the framework of the relevant situation, analysis and synthesis of the results of the dialogue.Conclusion. Based on the results of the experiment, the conclusion is made about the significant didactic potential for soft skills formation within teaching a foreign language. The cognitive and affective aspects of student training have been identified, contributing to the soft skills development. Specific stages of work are proposed, combining various forms of presenting information, professional competence and maintaining successful dialogue with different linguistic and cultural groups in a foreign language.
Typology of speech errors by native speakers (on the example of the French language)
Authors: Zykova A. V. , Nezhina L. A. 
Published: May 2024

Importance. The characteristics of the concepts “linguistic errors” and “linguistic norm” (subjective and objective) in the process of teaching native and foreign languages are given, which determines the significance of work in the modern multicultural space. The definitions of “speech culture” and “usus” are considered, and a typology of speech errors is described, which is divided according to aspects of the language: phonetics, grammar and vocabulary (stylistics).Research Methods. Examples of speech errors by French speakers are presented and analyzed based on the analysis of statistical data conducted by the French publications Le Figaro, Le Conseil Rédaction, Toploc, which clearly demonstrate how the language norm manifests itself and works.Results and Discussion. The conditions for describing the comparative and comparative analysis of contacting languages are substantiated as an important condition for identifying language difficulties and errors in language structures for the further application of this knowledge in the methodology of teaching both the native language and French and other foreign languages.Conclusion. The knowledge gained will allow students to improve their sociolinguistic competencies in the future, and the results of the study can be used in revising existing programs for the French language and organizing training in a more detailed consideration of the methodological support for teaching French: creating teaching aids, developing video materials and control.
Relationship between permanent upper anterior teeth and anthropometric facial measures in different populations
Authors: Longhi Maria Tereza de Moraes , Silva Rafaella Ugrin de Oliveira , Almeida Sâmara Cafa Silva , Esteves Alessandra , Rossi-Júnior Wagner Costa , Figueiredo Camila Helena Machado da Costa , Andrade Ana Luiza Dias Leite de 
Published: May 2024

Aim: The main purpose of this study was to conduct a narrative review investigating the possible relationship between permanent maxillary anterior teeth and anthropometric facial parameters in different populations. Methods: Searches were performed in the PubMed, BVS (Biblioteca Virtual em Saúde) and SciELO databases to identify relevant scientific articles using the following search terms: “maxillary anterior teeth”, “facial measurements” and “anthropometry”, in such a way that 218 publications were found. After application of inclusion and exclusion criteria, 13 publications remained for full-text reading. Results: All studies involved male and female samples and it was notorious that male measurements were unanimously higher than those obtained in the opposite sex. The age of the analyzed participants ranged from 17 to 60 years; however, a mean age of 18 to 25 years was the most investigated in literature. In addition, facial measurements including the bizygomatic width, interpupillary distance, intercanthal distance, interalar width and intercommissural width have been proposed to help determine the correct size of anterior teeth. Conclusion: It was concluded that despite the limited number of studies, some factors that influence dental and facial dimensions, such as sex and age, can be identified. However, there is no standardization of the facial or dental parameters used in the studies, a fact that makes it difficult to establish a universal ratio for clinical dental practice.
Discoveries in Transforming Student Engagement through Full-Day School Learning Motivation Research
Authors: Azizah Siti Hidayatul , Widyastuti Widyastuti 
Published: May 2024

This study examines the learning motivation levels among high-grade students at SD Islam Sabilillah Sidoarjo, utilizing a descriptive quantitative research approach with a sample size of 217 out of a total population of 506 students. Data analysis via descriptive statistical tests revealed that 68% of students demonstrated a moderate level of learning motivation, while 19% exhibited a high level and 13% had a low level. These findings highlight the students' ability to sustain learning motivation during academic activities at school and offer insights for enhancing motivation strategies in full-day school settings, with implications for educational institutions and policymakers.

Highlight:

Quantitative assessment of learning motivation in full-day school students.
Representative sample selection via proportionate stratified random sampling.
Insights for educational strategies and improved student engagement outcomes.

Keyword: Learning Motivation, Full-Day School, Student Engagement, Descriptive Quantitative Research, Educational Strategies
Decadal Land Use and Land Cover Transformation in Shaheed Bhagat Singh Nagar of Punjab Based on Geospatial Technology
Authors: Sohal Jaskaran Singh , Kaushal Arun , Arora Mohit , Loshali Dikesh Chandra 
Published: May 2024

Abstract

Land use and land cover (LU/LC) is observed to be the primary factor of environmental change on a worldwide scale. Timely and accurate information on LU/LC is very important for efficient planning and management activities. The present study mainly focused on land use and land cover change analysis in district Shaheed Bhagat Singh Nagar of Punjab using remote sensing and geospatial technology. Satellite data of IRS P6 LISS-III (2012 and 2022) were analysed for LU/LC mapping using visual interpretation techniques. The study area was divided into seven LU/LC classes i.e.: agriculture, built-up, waterbody, forest/tree clad area, riverine sand, algae bloom and fallow land /barren land/waste land in which agriculture covers maximum while riverine sand covers minimum area. Satellite derived NDVI and NDWI has been used to derive the spatial variability of vegetation and water. In decadal change the alterations encompass positive trends such as increased agricultural area (31.29%), as well as negative trends including decreased algae bloom (59.82%). Overall accuracy for LISS-III 2012 and LISS-III 2022 were 88.3% and 86.66% respectively with kappa coefficient value as 0.86, and 0.83, respectively. Hotspot areas with major changes were seen in Block Nawanshahr with major increase in built-up area, as well as in Block Saroya and Balachaur of study area with major decrease in Forest area.
Chimp Optimization Algorithm Contribution Support To Increases Energy Efficiency In UWASN
Authors: Kannappan A , Kolagani Nagesh 
Published: May 2024

Abstract

Underwater wireless Acoustic sensor network (UWASN) is employed to communicate between anchor nodes and the sink nodes. In this work, a novel Chimp optimization algorithm is deployed for underwater routing protocol communication, aiming to improve energy efficiency, packet delivery ratio, and throughput. In Chimp, the energy Optimization Algorithm solves the problems of propagation delay and improves battery life, network lifetime, and throughput. The proposed algorithm shows a better result in energy efficiency when compared to the existing buffalo algorithm, resulting in a Mean Delay of 79.17% and propagation delay of 74.35% than the existing counterpart. Especially compared to the buffalo algorithm, the Chimp algorithm has higher decision-making capacity and extended node range. The node range is set from 0 to 100, and the node performance is evaluated using MATLAB simulation software tools
High-Dimensional Semi-Parametric Model StatisticalInference for Model-Free and FDR Controlled Risk FeatureSelection
Authors: song xue-ting , lu zi-tong , gao yu-fan , Xiao Jian 
Published: May 2024

Abstract

Developing high-dimensional statistical inference method to identify the individual features associated with the response is very important in analyzing large-scale datasets from economics, finance, medicine, cancer studies, bioinformatics. However, themodern data sets collected often not only own the high-dimension property but alsoexhibit unknown relationships between the response and its explanatory features.Reliable statistical inference depends on an accurate modeling for the observed data.Such an involved modelling task can be done by the state-of-the-art semi-parametricmodel with few model assumptions. In this paper, based on high-dimensionalsemi-parametric model, we utilize the estimators of unknown parameters’ directions andsymmetrized data aggregation approach to develop a novel and model-free featureselection method for achieving fine-mapping of risk features while controlling the falsediscovery rate (FDR) of selection. The proposed method can be applied for the analysisof both continuous and discrete response data sets. The results of simulation studiesdemonstrate the proposed method has robust feature selection performance whilecontrolling FDR very well. The analysis results of a real ocean microbiome dataindicate our method indeed is effective to detect risk features.
Molecular cloning and characterization of a brassinosteriod biosynthesis-related gene PtoCYP90D1 from Populus tomentosa
Authors: Liu Yang , Tian Songqun , Tang Hu , Yao Xinzhuan 
Published: May 2024

Abstract

Brassinosteroids (BRs), one of the major classes of phytohormones are essential for various processes of plant growth, development, and adaptations to biotic and abiotic stresses. In Arabidopsis, AtCYP90D1 acts as a bifunctional cytochrome P450 monooxygenase, catalyzing C-23 hydroxylation in the brassinolide biosynthetic pathway. The present study reports the functional characterizations of PtoCYP90D1, one of the AtCYP90D1 homologous genes from Populus tomentosa. The qRT-PCR analysis showed that PtoCYP90D1 was highly expressed in roots and old leaves. Overexpression of PtoCYP90D1 (PtoCYP90D1-OE) in poplar promoted growth and biomass yield, as well as increased xylem area and cell layers. Transgenic plants exhibited a significant increase in plant height and stem diameter as compared to the wild type. In contrast, the CRISPR/Cas9-generated mutation of PtoCYP90D1 (PtoCYP90D1-KO) resulted in significantly decreased biomass production in transgenic plants. Further studies revealed that cell wall components increased significantly in PtoCYP90D1-OE lines but not in PtoCYP90D1-KO lines, as compared to wild-type plants. Overall, the findings indicate a positive role of PtoCYP90D1 in improving growth rate and elevating biomass production in poplar, which will have positive implications for its versatile industrial or agricultural applications.
Differential Genotoxicity of Polygoni Multiflori in Rat and Human: Insights from Ames Test and S9 Metabolic Activation System
Authors: Bak Su-Min , Back Seng-Min , Kim Da Yeon , Jeung Na-Young , Kim Nan-Young , Han Kang-Hyun , Kim Yong-Bum , Lee Byoung-Seok , Park Jun Hong , Cho Hee Jun , Lee Hee Gu , Ozden Ozkan , Park Seong-Hoon , Jung Soyoung 
Published: May 2024

Abstract

The Ames test is used worldwide to initially screen the mutagenic potential of new chemicals. In the standard Ames test, S. typhimuriumstrains (TA100, TA98, TA1535, and TA1537) and Escherichia coli (WP2uvrA) are treated with substances with/without cytochrome P450s (CYPs)-induced rat S9 fractions for identifying mutagens and pro mutagens. However, many substances show completely different toxicity patterns depending on whether the liver S9 fraction belongs to rats or humans. The natural product Polygoni Multiflori Radix(PMR)can also show bacterial reverse mutation, followed by the rat or human liver S9 fraction. While PMR elicits reverse mutations in the TA1537 strain in rat liver S9 but not in human liver S9, this mechanism has not been verified yet. To explain this, the differences in metabolic enzymes compositions commonly observed between rats and humans have been implicated. This study aimed to explore the key factors that cause differences in the genotoxicity of PMR between rat and human liver S9 metabolic enzymes. The results of next-generation sequencing (NGS) analysis showed that both rat and human metabolic enzymes caused similar mutations in TA1537. However, when the metabolic enzymes in each S9 fraction were analyzed using ion mobility tandem mass spectrometry (IM-MS), rat- and human-specific enzymes were identified among the cytochrome (CYP) family, especially aryl hydrocarbon receptor (AHR)-related CYPs. These findings suggest that CYP1A1 isoforms contribute to the mechanism of PMR in the Ames test. Therefore, an invitro Ames test might be more reliable in predicting genotoxicity for both rodents and humans. This will also help overcome the limitations of laboratory animal-based toxicity evaluations, which provide unreliable results due to interspecies differences between humans and rodents.
Tectonic control on great earthquake periodicity in south-central Chile.
Authors: Melnick Daniel , Aedo Diego , Cisternas Marco , Brill Dominik 
Published: May 2024

Abstract

Multi-millennial records of great megathrust earthquakes have highlighted differences in periodicity and recurrence behavior. Understanding tectonic processes responsible for these differences is relevant for fault mechanics and hazard models. Here, we present a new paleoseismic record inferred from raised beach ridges in the 2010 Maule earthquake (Mw 8.8) segment in south-central Chile that includes 24 interseismic periods over 4.5 kyr suggesting a weakly-periodic recurrence behavior. In turn, great earthquakes in the adjacent 1960 Valdivia earthquake (Mw 9.5) segment occurred with periodic recurrence over the same period. Both segments have similar amounts of trench sediments as well as rheological and geometrical boundary conditions, but Maule has a wider frontal accretionary wedge and several splay faults rooted in the seismogenic zone whereas Valdivia lacks splay faults and trench sediments are mostly subducted and underplated. These differences may have an impact on upper-plate compliance and megathrust friction, affecting earthquake size and recurrence periodicity.
Exploration and practice of "disease—drug" potential association prediction based on "Swanson framework+Bioinformatics"—a case study of Autism Spectrum Disorder
Authors: Lv Yanhua , Yuan Yuyang , Zhong Xiaoyun , Zhao Hongxia , Qu Baoqiang , Lu Xuechun , Yu Qi 
Published: May 2024

Abstract

Objective
Compared to traditional intermediate concepts, specific bioinformatics entities are more informative and higher directional. This study is based on the BITOLA system and combines bioinformatics methods to determine the intermediate concept which is key to improve efficiency of Literature-based Knowledge Discovery, proposes the concept of "Swanson framework + Bioinformatics", and conducts practice of Literature-based Knowledge Discovery to improve the scientificity and efficiency of research and development.
Methods
Firstly, detected the disease related genes (i.e. differentially expressed genes) according to the results of gene functional analysis as intermediate concepts to carry out Literature-based Knowledge Discovery. Taking the disease "Autism Spectrum Disorder(ASD)" as an example, the potential "disease-drug" association was predicted, and the predicted drugs were verified from the perspective of bioinformatics.
Results
Two drugs potentially associated with ASD were found: fish oil and forskolin, which were closely related to ASD in bioinformatics analysis results and literature verification.The two "disease-drug" association results showed better scientificity. The BIOINF-ABC+ model improves the accuracy of calculations by 76% compared to using the BITOLA system alone.In addition, it also shows high accuracy and credibility in literature verification.
Conclusion
The BIOINF-ABC+ model based on the "Swanson framework + Bioinformatics" has good practicality, applicability, and accuracy in conducting "disease-drug" association prediction in the biomedical field, and can be used for mining "disease-drug" relationships.
Increased non-relapse mortality in older people with allogeneic hematopoietic stem cell transplantation using fludarabine and myeloablative dose of busulfan-based regimen
Authors: Shinohara Akihito , Shindo Michiho , Sakaida Emiko , Uchida Naoyuki , Fukushima Kentaro , Nakazawa Hideyuki , Serizawa Kentaro , Kanda Yoshinobu , Kawakita Toshiro , Ikeda Takashi , Ohigashi Hiroyuki , Ito Ayumu , Wakayama Toshio , Matsuoka Ken-ichi , Fukuda Takahiro , Tanaka Junji , Atsuta Yoshiko , Nakasone Hideki 
Published: May 2024

Abstract

Fludarabine and myeloablative doses of busulfan-based regimens (FluBu4) are used in a wide age range as a reduced toxicity conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT). However, their tolerability in older people has not been adequately examined. This retrospective study analyzed data from Transplant Registry Unified Management Program in Japan. Patients who were >15 years old (y/o), had hematological malignancies, and received their first HSCT using FluBu4 between 2006 and 2017 were included. They were categorized into the younger group (<60 y/o, N = 1295) and the older group (≥60 y/o, N = 993). The 3-year overall survival (OS) rate after HSCT was significantly worse in the older group than in the younger group (P < 0.01, 39.9% versus 48.5%). The 3-year non-relapse mortality (NRM) was significantly higher in the older group than in the younger group (P < 0.01, 30.9% versus 23.0%), and the 3-year cumulative incidence of relapse was comparable between the groups. According to the multivariate analysis, age ≥ 60 years was significantly associated with poor OS (P < 0.01) and high NRM (P < 0.01). In subgroup analysis of the older group, the use of additional chemotherapeutic drugs to FluBu4 was significantly associated with poor OS (P = 0.01) and high NRM (P < 0.01). Total body irradiation was significantly associated with high NRM (P < 0.01) and 1-year incidence of sinusoidal obstruction syndrome (P < 0.01) but not with OS. Thus, FluBu4 should be used with caution in older people.
Potential application of bulk RNA sequence in MPNs clinic routine
Authors: Li Shenglong , Wu Sanyun , Xu Mingli , Li Xuedong , Zuo Xuelan , Wang Yingying 
Published: May 2024

Abstract

Philadelphia chromosome negative myeloproliferative neoplasms is a chronic hematological malignancy caused by driven mutations and non-driven mutations. It is considered tumor inflammatory disease, which characterized by dysregulated immune system including aberrant cytokine and abnormal immune cell. A comprehensive view of gene mutation and immune state for each classic myeloproliferative neoplasm patient during different disease stages is highly valuable in guiding treatment choice. Single cell RNA sequence, spatial transcriptome, mass cytometer and multiplex immune staining are very performant in exploring integrative gene mutation and/or immune landscape in oncology, However, they are not used in clinic routine because of its high cost and/or its high dependance of expertise. Bulk RNA sequence could be widely used in clinic with advantage of relative low cost. Furthermore, bioinformatic science progress rends possible to identify gene mutation and immune related genes with bulk RNA sequences simultaneously, this work aims to explore the potential value in interpretating gene mutation and immune landscapes of classic myeloproliferative neoplasm with bulk RNA sequence.