bluuebunny/crossref_metadata_2025_split huggingface dataset:
Initial stability and bone strain evaluation of the immediately loaded dental implant: an in vitro model study
Authors: Huang Heng‐Li , Chang Yin‐Yu , Lin Dan‐Jae , Li Yu‐Fen , Chen Kuan‐Ting , Hsu Jui‐Ting 
Published: November 2010

AbstractObjectives: The aim of this study was to evaluate the effects of cortical bone thickness and trabecular bone elastic modulus on the strain in the bone surrounding an immediately loaded implant. We also examined the correlations between bone structure and the following indices of primary implant stability: insertion torque value (ITV), Periotest value (PTV), and implant stability quotient (ISQ).Material and methods: The ITV, PTV, and ISQ were measured in 24 artificial jaw bone models representing cortical bone with four thicknesses (0, 1, 2, and 3 mm) and trabecular bone with four elastic moduli (137, 47.5, 23, and 12.4 MPa). Two loading conditions were applied (force of 130 N applied vertically and at 45° laterally), and the strains in the crestal region were measured by rosette strain gauges with a data acquisition system.Results: When the cortical bone thickness and the elastic modulus of trabecular bone decreased, the bone strains increased by 10.3–52.1% and 39–73.1%, respectively, for vertical loading and by 35–62% and 42.4–56.2% for lateral loading. The cortical bone thickness has a stronger correlation (R2=0.95–0.71) with ITV, PTV, and ISQ than the elastic modulus of trabecular bone (R2=0.89–0.59).Conclusions: The initial stability at the time of implant placement is influenced by both the cortical bone thickness and the elastic modulus of trabecular bone; however, these parameters are not totally linearly correlated with ITV, PTV, and ISQ. The placement of an immediately loaded implant in cases with thin cortical bone and/or weak trabecular bone can induce extreme bone strains and may increase the risk of implant failure. To cite this article:
Huang H‐L, Chang Y‐Y, Lin D‐J, Li Y‐F, Chen K‐T, Hsu J‐T. Initial stability and bone strain evaluation of the immediately loaded dental implant: an in vitro model study. Clin. Oral Impl. Res. 22, 2011; 691–698 doi: 10.1111/j.1600‐0501.2010.01983.x
Satisfaction Profiles in Men Using Intracavernosal Injection Therapy
Authors: Hsiao Wayland , Bennett Nelson , Guhring Patricia , Narus Joseph , Mulhall John P. 
Published: November 2010

ABSTRACT

Introduction
Intracavernosal injection therapy (ICI) is a well-established second-line therapy used in the treatment of erectile dysfunction (ED). Controversy exists as to whether oral phosphodiesterase type 5 inhibitors (PDE5i) or injection therapy lead to higher satisfaction.

Aim
This study addressed ICI satisfaction in a modern cohort of patients in the PDE5i era.

Methods
Patients on ICI for at least 6 months were included in our study. Patients were administered the International Index of Erectile Function (IIEF) at the initial visit. On subsequent visits, patients were administered the IIEF and the Erection Hardness Scale (EHS).

Main Outcome Measures
Study end points were change in baseline scores in the satisfaction domains (SD) of the IIEF, type of injection medication used, and predictors of satisfaction. Multiple logistic regressions were performed for predictors of satisfaction.

Results
One hundred twenty-two patients met inclusion criterion. Mean time to follow-up was 25 ± 12 months (range 6–106 months). Sixty-five percent of patients continued injections at the time of follow-up. When SD scores were examined, intercourse SD scores increased from 4.8 ± 1.7 at baseline to 12.3 ± 3.1 (P &lt; 0.01); overall SD scores increased from 4.1 ± 1.8 to 7.2 ± 2.0 (P &lt; 0.05). On multivariate analysis, predictors of satisfaction included older age (odds ratio [OR] = 2.1), younger partner age (OR = 2.5), clinically significant increase in the erectile function domain score (OR = 3.1), and attainment of a “fully rigid” erection (EHS 4) (OR = 6.8).

Conclusions
We have evaluated satisfaction in a modern cohort of ICI patients. While dropout rates are significant, for those patients who continue to inject, we have found high levels of satisfaction using the IIEF, the gold standard for evaluation of erectile function. On multivariate analysis, we found that older age, younger partner age, and fully rigid erections were predictors of increased satisfaction. ICI remains a robust second-line therapy in the treatment of ED even in the era of PDE5i.
The Impact of Oral ED Medication on Female Partners’ Relationship Satisfaction
Authors: McCabe Marita P. , O’Connor Elodie J. , Conaglen John V. , Conaglen Helen M. 
Published: November 2010

ABSTRACT

Introduction
Research has demonstrated that erectile dysfunction (ED) is a couple’s problem, and that treatment for this condition is likely to impact on the man and his partner.

Aim
The current study utilized a qualitative approach to evaluate the impact of treatment for ED on the female partner’s perception of changes in the relationship.

Main Outcome Measures
Analyses of the transcripts from the interviews.

Methods
In total, 96 men were treated for ED using tadalafil and then sildenafil (or vice versa) each for 3 months. Their female partners were interviewed 3 months after the commencement of treatment.

Results
The findings demonstrated an overall positive effect of the treatment. Female partners perceived improvements in emotional closeness, and communication, and reported that their relationship was more loving, less stressful, and more stable.

Conclusions
This study demonstrates the positive effects of treatment for ED on the female partner; in particular, on her perception of the quality of her relationship.
Five-Year Follow-Up of Peyronie’s Graft Surgery: Outcomes and Patient Satisfaction
Authors: Chung Eric , Clendinning Eric , Lessard Lauren , Brock Gerald 
Published: November 2010

ABSTRACT

Introduction
Graft surgery for Peyronie’s disease (PD) is associated with significant long-term risks.

Aim
To evaluate the clinical and functional outcomes of graft repairs with a minimum of 5-year follow-up.

Methods
A retrospective review of database and third party telephone survey was undertaken in all men who underwent reconstructive graft procedures for PD between May 1999 and May 2005.

Main Outcome Measures
Patient demographics, International Index of Erectile Function (IIEF-5) scores, and penile Doppler ultrasonography were performed preoperative. Follow-up assessments included surgical outcomes and overall patient satisfactions.

Results
A total of 86 patients with an average age of 54.6 (34 to 73) years underwent Peyronie’s graft repair. The average follow-up was 98 (61 to 120) months. Twenty patients received dermal graft whereas 33 patients underwent Tutoplast graft and 33 patients had Stratasis small intestinal submucosa graft. Penile curvature greater than 60 degrees was more common in the Tutoplast and Stratasis groups. Twelve patients used phosphodiesterase type 5 inhibitors or intracavenous agents preoperatively. At the time of review, only 46 (53%) patients were able to be contacted and consented for telephone interview. Although 6 months of postoperative follow-up showed excellent resolution, or significantly less, penile curvature, this figures decreased to 50% in dermal, 87% in Tutoplast, and 76% in Stratasis patients. Further penile length shortening was also reported on patient self-assessment at the recent follow-up. Worsening of IIEF-5 scores were noted with the development of erectile dysfunction was more pronounced in the diabetic cohort (P &lt; 0.01). The overall satisfaction on a 5-point scale was 2.6 with more than 65% of patients dissatisfied with the outcomes of the Peyronie’s graft surgery.

Conclusions
The recurrence of penile curvature, penile length loss, and the new-onset of ED are not uncommon sequelae and are associated with a significant patient dissatisfaction rate when a 5-year follow-up is achieved.
Measuring Acceptance of Milk and Milk Substitutes Among Younger and Older Children
Authors: Palacios Orsolya M. , Badran Joseph , Spence Lisa , Drake Mary Anne , Reisner Michele , Moskowitz Howard R. 
Published: November 2010

Abstract:  Appropriate nutrient‐dense foods and beverages are crucial for children for proper growth and development and to develop healthful lifelong habits. This study investigated children's (ages 8 to 16 y old) perception of sensory intensity, attribute liking and overall liking of unflavored and chocolate lactose‐free cow's milk and soy beverages. Products were not identified as to whether they were soy or milk. Children showed greater acceptance of lactose‐free cow's milk compared to milk substitute beverages, within flavor category. No differences in acceptance emerged by ethnic group (Caucasian, African American, Hispanic), but a large difference emerged by age group. All product acceptance differences perceived by older children reoccurred among the younger children and in the same direction, but the older children used a larger range of numbers, especially at the lower end, rather than at the higher end of acceptance. The effect of age is not a simple scaling bias but may suggest a reduced criticism by younger respondents of less‐acceptable products.Practical Application:  Appropriate nutrient‐dense foods and beverages are crucial for children. The prevalence of actual or self‐perceived lactose intolerance is a barrier for traditional fluid milk intake. This study evaluated acceptance by children of different ages for lactose free cow's milk and milk substitute soy beverages. While no differences in acceptance emerged by ethnic group (Caucasian, African American, Hispanic), large differences were noted among the age groups. Liking scores for lactose‐free cow's milk were higher than scores for milk substitute beverages, when the nature of the product was not identified. Younger children (ages 8 to 12 y old) tend to rate unacceptable products less critically, which means that manufacturers may mistakenly accept a poor tasting product based on these ratings.
Consumer Preferences for Fresh Tomato at the European Scale: A Common Segmentation on Taste and Firmness
Authors: Causse Mathilde , Friguet Chloé , Coiret Clément , Lépicier Mélanie , Navez Brigitte , Lee Monica , Holthuysen Nancy , Sinesio Fiorella , Moneta Elisabetta , Grandillo Silvana 
Published: November 2010

Abstract:  Although tomato flavor has not been a major goal for breeders, nowadays it becomes important as it is a subject of consumer complaint. A better knowledge of tomato consumer preferences, at the European level, should provide the basis for improvement of fruit quality and for market segmentation. In the framework of a large European project, 806 consumers from 3 countries, The Netherlands, France, and Italy, were presented with a set of 16 varieties representing the diversity of fresh tomato offer in order to evaluate their preferences. In parallel, sensory profiles were constructed by expert panels in each country. Preference maps were then constructed in each country revealing the structure of consumer preferences and allowing identification of the most important characteristics. Then a global analysis revealed that preferences were quite homogeneous across countries. This study identified the overall flavor and firmness as the most important traits for improving tomato fruit quality. It showed that consumer preferences from different European countries, with different cultures and food practices, are segmented following similar patterns when projected onto a common referential plan. Moreover, the results clearly showed that diversification of taste and texture is required to satisfy all consumers’ expectations as some consumers preferred firm tomatoes, while others preferred melting ones and were more or less demanding in terms of sweetness and flavor intensity. Detailed comparisons also showed the importance of the fruit appearance in consumer preference.Practical Application:  The consumer preferences for fresh market tomato were studied in 3 European countries. The main descriptors for further breeding for consumer satisfaction were identified. Four clusters of consumers were identified in the overall analysis, the 3 countries contributing the same way to each cluster. The impact of appearance in the preferences was also underlined.
Enumeration of Fungi in Fruits by the Most Probable Number Method
Authors: Watanabe Maiko , Tsutsumi Fumiyuki , Lee Ken‐ichi , Sugita‐Konishi Yoshiko , Kumagai Susumu , Takatori Kosuke , Hara‐Kudo Yukiko , Konuma Hirotaka 
Published: November 2010

Abstract:  In this study, enumeration methods for fungi in foods were evaluated using fruits that are often contaminated by fungi in the field and rot because of fungal contaminants. As the test methods, we used the standard most probable number (MPN) method with liquid medium in test tubes, which is traditionally used as the enumeration method for bacteria, and the plate‐MPN method with agar plate media, in addition to the surface plating method as the traditional enumeration method for fungi. We tested 27 samples of 9 commercial domestic fruits using their surface skin. The results indicated that the standard MPN method showed slow recovery of fungi in test tubes and lower counts than the surface plating method and the plate‐MPN method in almost all samples. The fungal count on the 4th d of incubation was approximately the same as on the 10th d by the surface plating method or the plate‐MPN method, indicating no significant differences between the fungal counts by these 2 methods. This result indicated that the plate‐MPN method had a number agreement with the traditional enumeration method. Moreover, the plate‐MPN method has a little laborious without counting colonies, because fungal counts are estimated based on the number of plates with growing colonies. These advantages demonstrated that the plate‐MPN method is a comparatively superior and rapid method for enumeration of fungi.Practical Application:  This article would give the benefit for application of techniques for food safety of fungi, because this article indicated that the plate‐MPN method is a superior and rapid method for enumeration of fungi.
GC‐MS Determined Distribution of Urinary Equol Producers as Affected by Age, Gender, and Repeated Ingestions of Soymilk
Authors: Ko Ting‐Fu , Tsai Hui‐Su , Lin Shu‐Mei , Liu Chi‐Dong , Learn Show‐Phon , Chiou Robin Y.Y. 
Published: November 2010

Abstract:  Status of equol excretion is likely a reflection of incidence risk of sex‐hormone related diseases and deserves research attention. In this study, urine samples collected from 182 volunteers after soymilk ingestion were subjected to equol quantification using GC‐MS. As categorized into male, female, and both genders and each category further classified into 6 age (year) categories, namely, <20, 21 to 30, 31 to 40, 41 to 50, >51 and overall, a trend indicating that the younger age the higher equol producer ratio was observed. For the >51 subjects, the corresponding producer ratios of males and females were 35.3% and 50.0%, respectively. Among the volunteers, 20 nonproducers were further recruited to ingest 1000 mL soymilk weekly for 16 wk and urines were analyzed bi‐weekly. As resulted, 8 of 20 nonproducers were induced to become equol producers. The observed change of nonproducers to equol producers induced by repeating ingestions of soymilk is of merit from the viewpoint of healthcare.Practical Application:  Excretion of equol after ingestion of isoflavones‐containing foods is likely to bear lower incidence risk of sex‐hormone related diseases, which attracts public attention. Based on observed possibility that nonproducers could be induced to become equol producers by repeating ingestions of soymilk, frequent intake of soybean‐derived foods is recommended.
Carboxymethyl Cellulose Coating and Low‐Dose Gamma Irradiation Improves Storage Quality and Shelf Life of Pear (Pyrus Communis L., Cv. Bartlett/William)
Authors: Hussain Peerzada R. , Meena Raghuveer S. , Dar Mohd A. , Wani Ali M. 
Published: November 2010

Abstract:  Carboxymethyl cellulose (CMC) coatings alone and in combination with gamma irradiation were tested for maintaining the storage quality and extending shelf life of pear. Matured green pears were CMC coated at levels 0.25% to 1.0% w/v and gamma irradiated at 1.5 kGy. The treated fruit including control was stored under ambient (temperature 25 ± 2 °C, RH 70%) and refrigerated (temperature 3 ± 1 °C, RH 80%) conditions. Irradiation alone at 1.5 kGy gave 8 and 4 d extension in shelf life of pear following 45 and 60 d of refrigeration, respectively. CMC coating at 1.0% w/v was effective in giving 6 and 2 d extension in shelf life of pear following 45 and 60 d of refrigeration, respectively. All combinatory treatments delayed the decaying of pear during postrefrigerated storage, but combination of 1.0% w/v CMC and 1.5 kGy irradiation proved significantly (P≤ 0.05) effective in maintaining the storage quality and delaying the decaying of pear. The above combinatory treatment gave an extension of 12 and 6 d in shelf life of pear during postrefrigerated storage at 25 ± 2 °C, RH 70% following 45 and 60 d of refrigeration.Practical Application:  Among the Pear varieties grown in the state of Jammu and Kashmir, William pear has 2nd leading position next to apple both in terms of cultivation and production. Being a climacteric fruit, it has short shelf life due to its fast ripening behavior. The short shelf life is a major constraint in the marketing chain of the produce. Microbial contamination of the produce also results in losses and poses potential health risks. We have evaluated the use of combinatory treatment of carboxymethyl cellulose coating (1.0% w/v CMC) and low‐dose gamma irradiation (1.5 kGy) to extend the shelf life of William pear. We found that the combinatory treatment of CMC coating (1.0% w/v) and low‐dose irradiation (1.5 kGy) appears to be promising method for improving the storage quality and extending the shelf life of the William pear. The combinatory treatment can be applied so as to facilitate servicing to farther markets.
Engineered Tissue Scaffolds With Variational Porous Architecture
Authors: Khoda A. K. M. B. , Ozbolat Ibrahim T. , Koc Bahattin 
Published: November 2010

Abstract
This paper presents a novel computer-aided modeling of 3D tissue scaffolds with a controlled internal architecture. The complex internal architecture of scaffolds is biomimetically modeled with controlled micro-architecture to satisfy different and sometimes conflicting functional requirements. A functionally gradient porosity function is used to vary the porosity of the designed scaffolds spatially to mimic the functionality of tissues or organs. The three-dimensional porous structures of the scaffold are geometrically partition into functionally uniform porosity regions with a novel offsetting operation technique described in this paper. After determining the functionally uniform porous regions, an optimized deposition-path planning is presented to generate the variational internal porosity architecture with enhanced control of interconnected channel networks and continuous filament deposition. The presented methods are implemented, and illustrative examples are presented in this paper. Moreover, a sample optimized tool path for each example is fabricated layer-by-layer using a micronozzle biomaterial deposition system.
Nonlinear time-dependent density functional theory investigation and visualization of ionizations in CO2 — Effects of laser intensities and molecular orientations
Authors: Fowe Emmanuel Penka , Bandrauk André Dieter 
Published: November 2010

Time-dependent density functional theory (TDDFT) studies of the ionization of CO2 by intense laser pulses Io ≥ 1 × 1014 W/cm2, at 800 nm are presented using the LB94 and the LDA potentials. Results reveal that for lower laser peak intensity, Io = 3.5 × 1014 W/cm2, the highest occupied molecular orbital (HOMO) contributes significantly to ionization owing to its lower ionization potential (IP), whereas the inner orbitals play the important role for higher laser peak intensities. Even though such lower orbitals have higher IP, the ionization process occurs when orbital densities are maximum along the direction of the laser field polarization. These findings are confirmed through the analysis of the images from the time-dependent electron localization function (TDELF) and the spectra of higher order harmonic generation (HOHG). Additionally, in spite of the IP difference between Kohn–Sham orbitals from LDA and LB94 potentials, our results show almost the same trend for both.
Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma
Authors: Auwerda Johannes , Yuana Yuana , Osanto Susanne , de Maat Moniek , Sonneveld Pieter , Bertina Rogier , Leebeek Frank 
Published: November 2010

SummaryMultiple myeloma (MM) is associated with an increased risk of venous thromboembolic (VTE) complications. Aim of this study was to measure microparticle-associated tissue factor (MP-TF) activity in patients with newly diagnosed MM before and after chemotherapy and to investigate whether MP-TF activity is associated with VTE. MP-TF activity was assessed in 122 newly diagnosed MM patients who were eligible for combination chemotherapy. MP-TF activity levels (17.6 fM Xa/min [8.6–33.2] (median [IQR]) were higher in untreated MM patients compared to normal healthy volunteers (4.1 fM Xa/min [2.3–6.6], p <0.001). MP-TF activity prior to the start of treatment was not different between patients who developed a VTE during follow-up (n=15) and those who did not (n=107). In 75 patients in whom plasma was obtained before and after chemotherapy, MP-TF activity decreased significantly (from 17.4 [10.2–32.8] to 12.0 [7.0–18.5] fM Xa/min, P=0.006). MP-TF activity remained, however, elevated in patients who developed VTE (15.1 [10.3–25.2]), in contrast to patients not developing VTE (11.4 [7.0–25.2], P<0.001). In conclusion, MP-TF activity is increased in patients with MM. Whether MP-TF activity has a pathogenetic role in VTE in MM patients remains to be established in future studies.
Role of intramural platelet thrombus in the pathogenesis of wall rupture and intra-ventricular thrombosis following acute myocardial infarction
Authors: Shan Leonard , Gao Xiao-Ming , Kiriazis Helen , Liu Yang , Lobo Abhirup , Head Geoffrey , Dart Anthony , Du Xiao-Jun 
Published: November 2010

SummaryLeft ventricular thrombus (LVT) and rupture are important mechanical complications following myocardial infarction (MI) and are believed to be due to unrelated mechanisms. We studied whether, in fact, wall rupture and LVT are closely related in their pathogenesis with intramural platelet thrombus (IMT) playing a pivotal role. Male 129sv and C57Bl/6 mice underwent operation to induce MI, and autopsy was performed to confirm rupture deaths. Haemodynamic features of rupture events were monitored by telemetry in conscious mice. Detailed histological examination was conducted with special attention to the presence of IMT in relation to rupture location and LVT formation. IMT was detected in infarcted hearts of 129sv (82%) and C57Bl/6 (39%) mice with rupture in the form of a narrow streak spanning the wall or an occupying mass dissecting the infarcted myofibers apart. IMT often contained dense inflammatory cells and blood clot, indicating a dynamic process of thrombus formation and destruction. Notably, IMT was found extending into the cavity to form LVT. Haemodynamic monitoring by telemetry revealed that rupture occurred either as a single event or recurrent episodes. Importantly, the anti-platelet drug clopidogrel, but not aspirin, reduced the prevalence of rupture (10% vs. 45%) and IMT, and suppressed the degree of inflammation. Thus, IMT is a key pathological element in the infarcted heart closely associated with the complications of rupture and LVT. IMT could be either triggered by a wall tear or act as initiator of rupture. IMT may propagate towards the ventricular chamber to trigger LVT.