bluuebunny/crossref_metadata_2025_split huggingface dataset:
MENTAL HEALTH PROFILE OF PROSPECTIVE STUDENTS OF THE FACULTY OF HEALTH SCIENCES AT WONOSOBO AL QUR'AN SCIENCE UNIVERSITY IN 2024
Authors: Sahli Muhamad 
Published: February 2025

Background: Students, typically aged 18-30, are individuals enrolled in higher education institutions and are granted special status due to their academic role. However, student life often involves heavy academic workloads, tight deadlines, and the constant pressure to perform well. These factors can take a toll on students' mental health, leading to stress, anxiety, and cognitive challenges. Objective: This study aimed to assess the mental health profile of prospective students at the Faculty of Health Sciences (FIKES), UNSIQ Wonosobo, in 2024. Methods: An analytic descriptive design was employed for this study, conducted at FIKES UNSIQ Wonosobo. The sample consisted of 160 prospective students from the regular class, selected using total sampling. Data was collected in September 2024 using a Self-Report Questionnaire that had been modified based on a literature review and validated for the study. Results: The study found that cognitive symptoms were most frequently reported by prospective students from the S1 Nursing program, with 24 respondents (70.5%) experiencing these symptoms. Many of these students had a vocational school (SMK) background (52.9%). Anxiety symptoms were also most prevalent among students from the S1 Nursing program, with 25 respondents (67.5%) affected. A majority of these students had a high school education background. These findings suggest a potential connection between educational background and the prevalence of mental health issues. This study underscores the mental health challenges faced by prospective students, emphasizing the need for support systems to help manage academic pressures and enhance student well-being.
Penerapan Akuntansi Forensik dalam Pendeteksian Kecurangan Melalui Psychological Capital Pada BPK RI Perwakilan Provinsi Sulawesi Barat
Authors: Edy Sri Amalia , AM Ahmad Mansur 
Published: February 2025

Fraud detection is action taken to discover fraud that has occurred or is occurring. In fraud Fraud detection is action taken to discover fraud that has occurred or is occurring. In fraud detection activities, auditors begin by identifying evidence that is an indication of the possibility of fraud. Therefore, auditors need the role of forensic accounting in tracing evidence aimed at solving financial problems which combines expertise in the fields of accounting, auditing and law which aims to prove the existence of fraudulent acts. The aim to be achieved is to see the influence of the application of forensic accounting on fraud detection through the auditor's psychological factors, namely psychological capital. This research focuses on detecting fraud committed by auditors at the Indonesian Financial Audit Agency Representative of West Sulawesi Province. The type of research used is quantitative research. The population in this study were all auditors at the BPK RI West Sulawesi Representative. The sampling technique used the sensis technique and the sample in this study was 51 people and used the quantitative method Structural Equation Modeling (SEM) with an intervening variable, namely psychological capital. The research results show that the application of forensic accounting has a positive and significant effect on fraud detection. Psychological capital has a positive and significant effect on fraud detection. Psychological capital has a positive and significant effect on fraud detection. Apart from that, this research can be used as input for auditors in their ability to prove the existence of fraud in the implementation of audit procedures.
Operasionalisasi dan Faktor-Faktor yang Mempengaruhi Efektivitas Audit Internal: Systematic Literature Review
Authors: Syafithri Yuyun , Wahyudi Tertiarto , Yusrianti Hasni , Meutia Inten 
Published: February 2025

The purpose of this study is to present how internal audit effectiveness can be operationalized. The researcher used a structured literature review method obtained from reputable electronic databases from 2019 to 2024 resulting in 35 studies selected based on inclusion and exclusion criteria. The findings of this study comprehensively present the developments, factors, indicators, and future research suggestions related to internal audit effectiveness. This study offers a contribution to research and practice related to improving internal audit effectiveness conducted in both the public and private sectors that can be used as a consideration for conducting future research in this area.
Challenging Perceptions: A Post-Representational Reading of The Fate of Fausto
Authors: Jordan Mairéad 
Published: February 2025

As the ‘greening’ of literature for children and young adults continues apace in a time of climate crisis, much research in the field adopts interpretative approaches that analyse representations of nature and the non-human in literature for children and young adults. This article adopts an alternative post -representational approach in its exploration of entanglements of materiality, aesthetics, and paratextuality in The Fate of Fausto by author–illustrator Oliver Jeffers. 1 I argue that The Fate of Fausto presents a performative, material-discursive space, demonstrating intra-actions between creator, process, product, and reader that transcend a limited representational analysis. I propose that this entangled analysis provides deeper insight into the transformative potential of visual literature in reshaping the young reader's perceptions of the world, and also demonstrates the efficacy of a post-representational approach in revealing such potential. The adoption of this approach could yield fruitful results in future ecocritical research on visual narratives for children and young adults.
International Civil Law Aspects of International Marriage: A Comparative Perspective of Indonesian and Japanese Law
Authors: Sugiastuti Natasya Yunita , Rudyanto Bambang , Dancar Aleksander 
Published: February 2025

International marriage is a marriage between two parties with different nationalities. As every country has its own civil law that regulates marriage, international marriage involves aspects of international civil law. This study raises two key issues: first, the determination of applicable laws related the material and formal conditions of marriage; and second, the citizenship of spouses as well as children in an international marriage. The discussionadopts a comparative perspective, focusing on Indonesian and Japanese legal systems. Â Â This study employs normative legal research, utilizing a statutory and comparative approach, analyzing primary, secondary, and tertiary legal materials through qualitative methods and inductive conclusions. Results of the study indicate conceptual similarities between Indonesian and Japanese law in the area under study. First, material conditions of international/mixed marriage are determined based on the principle of lex patriae, while formal conditions are based on the lex loci celebration. principle Second, international marriage does not cause the spouses to automatically lose their own or obtain the citizenship of their spouse but can only obtain the citizenship of their spouse through a naturalization application. Children born in international marriages obtain citizenship based on the principle of ius sanguinis, and if this leads to dual citizenship, within a certain period of time the child must choose one of the nationalities. The existing literature concerning international marriage indicates that there is a gap of research with comparative approach between Indonesian and Japanese law. Thus, in addition to enriching the study of law related to international marriage, the results of this study can be used as educational materials for the Indonesian diaspora in Japan and vice versa.
Insight into loading, release, and anticancer activities of the methanol hybridized glauconite nano-sheets as a potential carrier of cisplatin: equilibrium and release kinetics
Authors: Alfassam Haifa E. , Nasser Nourhan , Othman Sarah I. , Alharbi Hanan M. , Alenazi Noof A. , Rudyani Hassan A. , Allam Ahmed A. , Al Zoubi Wail , Abukhadra Mostafa R. 
Published: February 2025

Advanced silicate nano-sheets as exfoliated and separated layers were developed from natural glauconite and hybridized with methanol, producing a methoxy exfoliated structure (Mth/EXGL). The structure was assessed as an enhanced carrier of the cisplatin drug (CSPN) with significant loading, release, and cytotoxicity properties. The methoxy form of exfoliated glauconite showed better loading properties (327.7 mg/g) than the exfoliated sample (202.4 mg/g) as well as the raw sample (119.3 mg/g). This enhancement was assigned to the incorporated active loading centers after the methanol hybridization step, which is in agreement with the steric studies and determined active site density (Nm = 45.5 mg/g (Mth/EXGL), 38.4 mg/g (EXGL), and 26.3 mg/g (glauconite). Moreover, each site across the interface of Mth/EXGL has the capacity to be loaded with 8 CSPN molecules, donating multi-molecular mechanisms and their loading in vertical orientation. The CSPN loading energy value (&lt;8 kJ/mol) into Mth/EXGL reflected the dominant impact of the physical mechanisms, including electrostatic attractions and hydrogen bonding. The recognized release profile demonstrates continuous and controlled behavior that can extend up to 110 h at pH 7.4 and 170 h at pH 5.5. This releasing behavior is regulated by two main processes (diffusion and erosion) based on the release kinetic findings. Also, Mth/EXGL as a carrier of CSPN induces its cytotoxic effect on human cervical epithelial tumors (HeLa) (0.65% cell viability) as compared to the free form of CSPN (6.6% cell viability). The Mth/EXGL is recommended as a delivery system for CSPN considering its determined loading, release, and cytotoxicity properties.
Pulsed field ablation for atrial fibrillation: a comprehensive bibliometric analysis of research trends and emerging Frontiers
Authors: Li Li , Xie Bin 
Published: February 2025

BackgroundAtrial fibrillation (AF) is the most prevalent cardiac arrhythmia worldwide, posing significant health burdens. Pulsed field ablation (PFA) is an emerging non-thermal technique that is gaining traction due to the ability to selectively target myocardial cells and minimize damage to surrounding tissues. We conducted a comprehensive bibliometric analysis of PFA use in AF treatment to map research trends, collaborations, and future directions.MethodsWe extracted data from the Web of Science Core Collection on September 6, 2024, using search terms related to PFA and AF. Publication trends, citation trajectories, collaborative networks, and keyword co-occurrences were analyzed utilizing tools such as Bibliometrix R, VOSviewer, and CiteSpace.ResultsIn total, 217 publications were retrieved. The number of publications increased rapidly from 2019 to 2024, with a notable surge occurring after 2022. Contributions from the United States, Germany, and China accounted for more than 60% of all publications. The institution with the largest output was The Icahn School of Medicine at Mount Sinai. The most productive journals were Europace and the Journal of Interventional Cardiac Electrophysiology. Prolific authors were identified, underscoring significant international collaborations. The most cited publications highlighted the efficacy and safety of PFA. Keywords with strong recent citation bursts included “tissue”, “cardiomyopathy”, and “closed chest ablation”.ConclusionPFA is becoming established as a viable alternative for AF ablation, showing promising safety and efficacy. This bibliometric analysis confirmed the growing scientific interest and collaborative efforts in this field, suggesting that robust future developments will occur.
Assessment of postoperative prognosis in patients with acute ST-segment elevation myocardial infarction after PCI using LRP1
Authors: Guan Jingwen , Xu Yikang , Liu Limin , Su Mengran , Ma Jingru 
Published: February 2025

PurposeTo evaluate the prognostic value of Low-density lipoprotein receptor-related protein 1 (LRP1) in patients with acute ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI).MethodThis prospective study included 96 STEMI patients who underwent PCI and 19 control subjects with normal coronary arteries. Coronary blood was taken from both groups, and LRP1 expression levels were quantified using real-time quantitative PCR (qPCR). The STEMI patients were stratified into low, middle, and high LRP1 groups based on tertiles of LRP1 expression. The primary endpoint was the occurrence of major adverse cardiovascular events (MACE) during a six-month follow-up period post-PCI.ResultsLRP1 expression in arterial blood was significantly lower in the STEMI group [0.63(0.23,1.1)] compared to the control group [1.5(0.84,1.85)] (P &lt; 0.05). The incidence of MACE showed an increasing trend across the LRP1 tertiles: 6.7% (95% CI: 1.9–21.3%) in the low LRP1 group, 22.6% (95% CI: 11.4–39.8%) in the middle LRP1 group, and 41.9% (95% CI: 26.4–59.2%) in the high LRP1 group. The high LRP1 group exhibited a significantly higher MACE rate compared to the low LRP1 group (P &lt; 0.05). Spearman's rank correlation analysis revealed positive correlations between LRP1 and both NT-proBNP and cTnT (r = 0.349, 95% CI: 0.156–0.515, P &lt; 0.001; r = 0.328, 95% CI: 0.133–0.497, P = 0.001, respectively), and a negative correlation with LVEF values (r = −0.285, 95% CI: −0.460 to −0.087, P = 0.006). Receiver operating characteristic (ROC) analysis identified an LRP1 expression threshold of 0.79 for predicting MACE within six months post-PCI, with a sensitivity of 81.8% (95% CI: 61.5–92.7%), a specificity of 70% (95% CI: 58.5–79.5%), and an area under the curve (AUC) of 0.789 (95% CI: 0.688–0.890, P &lt; 0.001).ConclusionLRP1 expression appears to be an independent predictor of MACE in STEMI patients and may have prognostic value for short-term outcomes following PCI.
Association of serum inflammatory markers in early-pregnancy with the risk for gestational diabetes mellitus: a prospective cohort in Shenzhen, China
Authors: Wang Yijin , Ren Qinqin , Yuan Hui , Wang Yang , Liu Yao , Wei Yuanhuan , Sun Ruifang , Yang Hongguang , Tian Ping , Yang Jianjun , Deng Guifang 
Published: February 2025

IntroductionThe systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) have recently been reported as novel inflammatory markers of diabetes. However, the associations of SII and SIRI with the risk of gestational diabetes mellitus (GDM) are unclear. In our study, we explored the association between the SII and SIRI in early pregnancy and the risk of GDM in pregnant women.MethodsA prospective cohort of 1,505 pregnant women were recruited at 6–13 weeks of gestation in 2019 and 2020 in Shenzhen, China. SII and SIRI were determined by calculating the composite inflammation indicators from routine blood test results at 6–13 weeks of gestation, and an oral glucose tolerance test was conducted at 24–28 weeks of gestation to diagnose GDM. Logistic regression was used to analyse the correlations between the incidence of GDM and SII and SIRI. Using a restriction cubic spline with baseline SII and SIRI as continuous variables, the dose–response associations between the incidence of GDM and SII and SIRI were explored.ResultsFollowing Ln-transformation of the SII and SIRI, multivariate models showed that Ln (SII) (odds ratio [OR] = 1.759; 95% confidence interval [CI]: 1.272–2.432) and Ln (SIRI) (OR = 1.556; 95% CI: 1.187–2.042) were positively associated with the risk of GDM in a dose-dependent manner. The OR for the highest quartile of SII compared with the lowest quartile for the risk of GDM was 2.080 (95% CI: 1.447–2.990), and the OR for the highest quartile of SIRI compared with the lowest quartile was 1.694 (95% CI: 1.170–2.452). The restricted cubic spline model confirmed a linear association between Ln (SII) and Ln (SIRI) with the risk of GDM (p-nonlinear &gt; 0.05).DiscussionHigher SII and SIRI in early pregnancy are associated with an increased risk of GDM. As novel, valuable, and convenient indicators of inflammation, SII and SIRI could be used to a potential predictor for GDM in early pregnancy.
Efficacy and safety of parathyroid perfusion assessment by fine-needle prick during thyroid surgery: a prospective study
Authors: Wang Peisong , Xue Haowen , Wang Xin , Xue Shuai 
Published: February 2025

ObjectiveThis prospective study aimed to analyze the efficacy and safety of fine-needle prick (FNP) in the assessment of parathyroid gland (PG) perfusion during thyroid surgery.MethodsA total of 147 patients with papillary thyroid carcinoma (PTC) who underwent lobectomy with therapeutic unilateral central lymph node dissection (CLND) performed by the same surgeon at the First Hospital of Jilin University between June and September 2024 were included in this prospective study. Following removal of the thyroid and unilateral central lymph nodes, indocyanine green (ICG) was prepared and administered intravenously. Fluorescence signals and images were captured using a near-infrared system to obtain the ICG1 score. Approximately 5–10 min thereafter, the fluorescent signal dissipated, after which the preserved PG was evaluated using FNP. An FNP score was established based on oozing blood from the parathyroid. After hemostasis was achieved by compression with gauze, ICG was reinjected to reassess PG perfusion, which yields the ICG2 score.ResultsIn 13 patients, only one parathyroid was identified, while the other was inadvertently excised during surgery. A total of 269 (95.73%) parathyroids were evaluated, with consistent scores observed between the use of the ICG1 and FNP methods. However, in six congested PGs with a darkened appearance, the FNP method could not accurately assess blood supply due to the slow oozing of accumulated blood following the procedure. The Spearman’s correlation coefficient between the ICG1 and FNP methods was 0.973 (p &lt; 0.001), demonstrating strong concordance in determining PG blood supply. Furthermore, the identical ICG1 and ICG2 scores indicated that FNP did not adversely affect PG perfusion.ConclusionThe FNP test could represent a safer, simpler, and more reliable alternative to ICG for the assessment of PG perfusion. However, further validation in patients undergoing total thyroidectomy and bilateral CLND is warranted.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR2400084531.
The value of targeted CXCR4 18F-AlF-NOTA-pentixafor PET/CT for subtyping primary aldosteronism
Authors: Peng Yushi , Chen Fangansheng , Yao Rui , Lan Junping , Fu Yinuo , Ye Kaifeng , Wang Zhiqiang , Zhao Qianxiu , Ji Xiaowei , Xia Kang , Zhu Guoqing , Zheng Kewen , Gu Xuemei , Tang Kun 
Published: February 2025

ObjectiveThe study aimed to investigate the diagnostic value of 18F-AlF-NOTA-Pentixafor PET/CT in subtyping primary aldosteronism (PA).MethodsThis study enrolled 88 patients with PA or nonfunctional adenoma (NFA) for 18F-Pentixafor PET/CT scan. Of these, 20 patients underwent adrenal venous sampling (AVS), and 65 underwent adrenalectomy and postoperative follow-up.ResultsIn 88 patients, 76 were diagnosed with unilateral PA (UPA), 4 were diagnosed with bilateral PA (BPA), and 8 were diagnosed with NFA, resulting in a total of 95 lesions. To identify UPA, visual analysis received a specificity of 94.12% and a sensitivity of 89.74%. The optimal cutoff values for SUVmax at 5.45, the lesion-to-normal adrenal ratio (LAR) at 1.43, and lesion-to-liver ratio (LLR) all yielded a specificity of 100% and a sensitivity of 79.49%, 83.33%, and 80.77%, respectively. In 15 adrenal lesions with similar uptake to contralateral and adjacent normal adrenal tissue (defined as warm lesions), 7 were confirmed as UPA, 4 were confirmed as BPA, and 4 were confirmed as NFA. Furthermore, among the 20 patients who underwent AVS, the concordance rate of AVS and PET/CT visual analysis for PA subtyping was 65.00%.ConclusionsThe CXCR4-targeted 18F-AlF-NOTA-pentixafor PET/CT is a valuable noninvasive tool for diagnosing UPA, demonstrating high sensitivity and specificity. More attention should be paid to warm adrenal lesions for their high diagnostic ambiguity probability.
Association between female waist-hip ratio and live birth in patients undergoing in vitro fertilization: a retrospective cohort study
Authors: Ye Mingming , Yang Yingying , Cai Chenting , Li Zhen , Qiu Andong , He Jia , Ma Jing , Bukulmez Orhan , Norman Robert J. , Teng Xiaoming , Chen Miaoxin 
Published: February 2025

BackgroundMaternal obesity is associated with adverse pregnancy outcomes. It negatively affects IVF/ICSI outcomes and offspring health. However, it is unclear whether waist-hip ratio (WHR) has an impact on outcomes of in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles.MethodsA retrospective cohort study screened 943 patients who underwent IVF/ICSI treatment between February and June 2020 in Shanghai, China, and 828 patients were finally included in the analyses. The body weight, height, waist circumference and hip circumference were measured before ovarian stimulation, and their IVF/ICSI outcomes were followed up. The cut-off point of WHR was determined by the area under the receiver operating characteristic (ROC) curve. Live birth rate from the first embryo transfer cycle was the primary outcome. The secondary outcomes included cumulative live birth, miscarriage rate and birthweight.ResultsWomen with relatively high WHR (≥0.783) showed lower live birth rate (adjusted odds ratio (aOR): 0.657, 95%CI: 0.466-0.926), lower cumulative live birth rate (aOR: 0.580, 95%CI: 0.413-0.814), and higher miscarriage rate (aOR=2.865, 95%CI: 1.300-6.316) as compared with those with low WHR (&lt;0.783), independently of BMI. Joint WHR and BMI analyses showed that, compared with the reference group (those with low WHR and normal weight), those with high WHR and normal BMI had lower live birth rate (aOR=0.653, 95%CI: 0.447-0.954) and cumulative live birth rate (aOR=0.600, 95%CI: 0.413-0.872), and higher miscarriage rate (aOR=2.865, 95%CI: 1.229-6.676), Whereas the patients with both high WHR and high BMI only showed a significant lower cumulative live birth rate (aOR=0.612, 95%CI: 0.404-0.926). Moreover, there was no significant association between BMI and pregnancy outcomes, or between maternal WHR and birth weights.ConclusionsOur results demonstrated that higher WHR was associated with lower fecundability in women undergoing IVF/ICSI cycles, independently of BMI. Interestingly, the adverse effects of central obesity were more evident in patients with lower BMI. Thus WHR appears to be a better predictor of female fertility treatment outcomes as compared with BMI.