bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Study on The Clinical Medical Students' Awareness of Cardiopulmonary Resuscitation- A Comparative Study Between Syrian Private University and Damascus University
Authors: Abdullah Nour Alhouda Mahmoud , Rhibani Lubna Mohamad Hassan , Rekmani Najwa fajr 
Published: April 2024

Abstract

Background:
The importance of this research lies in that it sheds light on a significant medical issue, that is clinical medical students’ awareness of cardiopulmonary resuscitation, as well as comparing this awareness between two major universities in Syria, namely Damascus university and Syrian Private university (SPU). The purposes of this research are to determine the knowledge score on this issue, indicate its importance in practical life, reveal the weak cognitive points, and compare this awareness between the two universities, in an attempt to correct the defect and restore the deficiency in order to achieve a healthier and safer life.
Materials and Methods:
A cross-sectional study was conducted on a sample of clinical medical students at both Damascus university and SPU, by randomly publishing a questionnaire among these students over a period of time spanning from 24/10/2023 to 7/1/2024.
Results:
The sample included 445 students, most of whom were at Damascus university with a percentage of 64% and 58.9% of the sample were female. The results have showed that knowledge score at Damascus university is higher than that at SPU, with the first recording 7.35 points out of 10 and the latter recording 4.15
Conclusion:
This study reveals the number of flaws in the awareness of cardiopulmonary resuscitation among medical students, who are supposed to be the most educated people on this extremely important medical procedure; since correct knowledge and application of it in the appropriate time can help save the lives of many people.
Does Eta Protein Differentiate Rheumatoid Arthritis from Psoriatic Arthritis?
Authors: Kor Ahmet , Orhan Kevser , Maraş Yüksel , Oğuz Esra Fırat , Unan Mehtap Kalçık , Dilek Gamze , Erten Şükran , Nas Kemal 
Published: April 2024

Aim:
The clinical symptoms and laboratory markers of Rheumatoid Arthritis
(RA) and Psoriatic Arthritis (PsA) can be very similar, so making a differential diagnosis
between these two diseases is often difficult. Serological parameters to be used in differential
diagnosis can guide the clinician. This study aimed to investigate the usability
of 14-3-3η (eta) protein as a biomarker in the differential diagnosis of PsA and RA, and
the relationships between eta protein and disease activity scores and joint erosions in
PsA and RA.

Methods:
54 PsA patients, 53 RA patients, and 56 healthy individuals were included in
this study. The ELISA (Enzyme-Linked ImunoSorbent Assay) kit was used as a quantitative
sandwich enzyme immunoassay technique to detect human eta protein levels. Receiver-
operating Characteristic (ROC) curves analysis was used to determine the sensitivity
and specificity of the eta protein.

Results:
Eta protein levels were found to be significantly higher in the RA group than in
the PsA [B: -0.341, OR (95% CI): 0.711 (0.556-0.909), p: 0.007] and control [B: -0.225,
OR (95% CI): 0.798 (0.641-0.995), p: 0.045] groups. Eta protein median values were significantly
higher in patients with joint erosion than in those without [β= 0.151, OR (95%
CI): 1.163 (1.003-1.349), p: 0.046].

Conclusion:
Eta protein levels are higher in the serum of RA patients than PsA and are
associated with joint erosion. Eta protein may be a potential biomarker in the differential
diagnosis of RA and PsA. It may represent a possible therapeutic step in the pathophysiological
pathways in the development of joint erosion.
Preparation and Physicochemical Properties of a Thermosensitive Hydrogel-based Lipopeptide Biosurfactant
Authors: Afsharipour Sepehr , Estabragh Mohammad Amin Raeisi , Namaki Amirhossein , Ohadi Mandana , Moshafi Mohammad Hassan , Banat Ibrahim M. , Dehghannoudeh Gholamreza 
Published: April 2024

Background:
Temperature-sensitive (thermo-sensitive) formulations are a novel drug
delivery dosage form that shows bio-inspired behavior in various applications. The structure and
properties of a thermosensitive polymer are critical in designing an intelligent biometric polymer that
contains lipopeptide biosurfactants.

Objectives:
In this study, thermo-sensitive hydrogels with lipopeptide biosurfactants as a potential
wound dressing dosage form were formulated and examined regarding physicochemical properties.

Methods:
The lipopeptide biosurfactants were isolated from the Acinetobacter junni B6 bacterial
strain and loaded on a formulation of poloxamer 407® and carboxymethyl cellulose as a gelling
agent. Numerous experiments were carried out to evaluate the physicochemical properties of these
formulations, such as the stability, spreadability, release profile, and kinetic.

Results:
The formulation (Poloxamer 407® (19% w/v), carboxymethyl cellulose (2% w/v), lipopeptide biosurfactants (5mg/mL), benzyl alcohol (1% v/v), and 0.1mL polyethylene glycol 400) was
select as the optimum formulation. The selected formulation released 26.9% of the lipopeptide biosurfactants with anomalous transport kinetics after 10 hours.

Conclusions:
The results showed that a thermo-sensitive formulation could help achieve a sustained
release of lipopeptide biosurfactants and potentially be used as a dressing formulation for wounds in
future studies.
Adolescents' Knowledge and Attitudes about Contraception, Sexuality, Sexually Transmitted Diseases, and Pelvic Health
Authors: Erceg Ivkosic Ivana , Fures Rajko , Bojcic Ruzica , Hrgovic Zlatko , Fures Dora , Cosic Vesna , Lez Cvjetko , Stanic Zana , Bulic Luka 
Published: April 2024

Background:
Sexually Transmitted Infections (STIs) can cause serious health complications, including pelvic inflammatory disease, infertility, ectopic pregnancy, adverse pregnancy outcomes, and cervical cancer. Adolescents and young adults are particularly vulnerable to STIs due to
risk-taking behaviors, multiple sexual partners, and inconsistent condom use. Our study aimed to
examine the knowledge about contraceptive methods and sexually transmitted infections, and attitudes toward sexual health education among adolescents in Croatia.

Methods:
The participants were high school students aged 16 to 18 years. The study was conducted
at Antun Gustav Matoš Gymnasium, Zabok. We obtained study data via an anonymous survey.

Results:
The study included 204 adolescents in their final years of high school. The total number of
adolescents who had sexual intercourse was 47 (23%). The percentage of sexually active female
and male adolescents was 21% and 27%, respectively. In the surveyed group of adolescents, 86%
had never heard of subcutaneous progestin implants and 72% had never heard of contraceptive
sponges. All adolescents had heard of oral contraceptives and condoms. In the surveyed group of
adolescents, 58% had never heard of trichomoniasis and 10% had never heard of HSV. All adolescents had heard of HIV and syphilis. A total of 147 (72%) of the surveyed adolescents believed it as
necessary to provide health education in schools.

Conclusion:
The initiation of sexual activity among adolescents in Croatia remains unchanged
when compared to previous studies. Their current knowledge of sexually transmitted diseases and
contraceptive methods should be improved through continuous, well-designed, and comprehensive
sexual health education.
Validating the Distinctiveness of the Omicron Lineage within the SARS-CoV-2 based on Protein Language Models
Authors: Dong Ke , Gao Jingyang 
Published: April 2024

Introduction:
Variants of concern were identified in severe acute respiratory syndrome
coronavirus 2, namely Alpha, Beta, Gamma, Delta, and Omicron. This study explores the mutations
of the Omicron lineage and its differences from other lineages through a protein language model.

Methods:
By inputting the severe acute respiratory syndrome coronavirus 2 wild-type sequence into
the protein language model evolving pre-trained models-1v, this study obtained the score for each
position mutating to other amino acids and calculated the overall trend of a new variant of concern
mutation scores.

Results:
It is found that when the proportion of unobserved mutations to observed mutations is 4:15,
Omicron still generates a large number of newly emerging mutations. It was found that the overall
score for the Omicron family is low, and the overall ranking for the Omicron family is low.

Conclusion:
Mutations in the Omicron lineage are different from amino acid mutations in other lineages.
The findings of this paper deepen the understanding of the spatial distribution of spike protein
amino acid mutations and overall trends of newly emerging mutations corresponding to different
variants of concern. This also provides insights into simulating the evolution of the Omicron lineage.
Comparative characteristics of the effectiveness of spinal anesthesia based on bupivacaine in combination with different intrathecal doses of dexmedetomidine
Authors: Shchegolkov E.E. , Loskutov O.A. 
Published: April 2024

Background. To increase the quality of a block, corresponding adjuvants are used intrathecally. However, currently, the interrelation between different doses of intrathecal dexmedetomidine as an adjuvant, differential analgesia, and the effectiveness of a spinal block is not adequately elucidated. The purpose: to conduct a comparative analysis on the effectiveness of motor (MB) and sensory block (SB), as well as to evaluate the clinical efficiency of analgesia during spinal anesthesia based on bupivacaine in combination with various intrathecal doses of dexmedetomidine. Materials and methods. The study included 150 patients with a mean age of 41.3 ± 8.2 years who underwent biportal endoscopic discectomy. Participants were divided into the following groups: group 1 (n = 30) — intrathecal administration of 2.5 ml bupivacaine combined with intrathecal administration of 2.5 µg dexmedetomidine; group 2 (n = 30) — intrathecal use of 2.5 ml bupivacaine with intrathecal administration of 5 µg dexmedetomidine; group 3 (n = 30) — intrathecal administration of 2.5 ml bupivacaine combined with intrathecal administration of 10 µg dexmedetomidine. In the groups, the sensory and motor status of patients and the level of analgesia were assessed. Results. The time of a SB onset was 22.78 ± 2.04 % higher in group 1 than in group 2 and 37.42 ± 2.75 % higher compared to group 3. The time of a MB onset in group 1 was 9.16 ± 1.32 % higher than in group 2 and 20.17 ± 2.36 % higher compared to group 3. In group 1, the time of a two-segment sensory regression was 21.38 ± 2.18 % lower than in group 2 and 36.40 ± 2.81 % lower than in group 3. The duration of a MB in group 3 was 18.23 ± 2.21 % higher compared to group 2 and 42.39 ± 3.05 % higher than in group 1. In group 3, the indicators of differential analgesia were 110.74 ± 4.53 % higher compared to group 2 and 202.39 ± 5.72 % higher than in group 1. Conclusions. Increasing the intrathecal dose of dexmedetomidine resulted in a reduction in the time of a sensory block onset, while the duration of a motor block increased. The indicators of analgesia duration also directly proportionally increased with the escalation of dexmedetomidine dosage.
Analysis of volatile compounds in roasted Liberica Coffee in the Philippines by gas chromatography mass spectrometry
Authors: Dimaano Francesca Villamin , Barcelon Eufemio G , Braga Jason , Braga Jason , Mojica Analyn 
Published: April 2024

The study is aimed at evaluating volatile compounds of Liberica coffee (Coffea liberica) collected from Lipa Batangas. Sample analysis was performed using Static Headspace Gas Chromatography. The roasting process also generated furans, pyridines, aldehydes ,and pyrazines potent volatile compounds in Liberica beans including unique volatile compounds including Terpinene 4-acetate (0.65%) and trans-β-Ocimene (0.47%). Furthermore, the presence of the abovementioned compounds revealed the essential marker as Liberica coffee beans. This finding may help to add more information with regards to the volatile compounds of Liberica Coffee.
Religious Moderation and Family Resilience in the City of Malang, Indonesia: The Historical Perspectives of the Islamic Law
Authors: Fadil Fadil , Marwinata Pepy , Jannah Shofiatul , Siroj A. Malthuf 
Published: April 2024

Religious moderation is a moderate attitude or perspective in religion that is fair and balanced. A moderate mindset and behavior in the family is very significant for married couples to avoid things that can damage the honor and dignity of the family. The research method used is an empirical legal study with an approach to the history of Islamic law. Data was collected through in-depth interviews with a number of informants namely, academics, housewives, teachers and self-employed people. While document studies are carried out by analyzing journal articles, books and various references related to the discussion. The research found that a moderate religious perspective and attitude are critical for family life. Family resilience strategies include belief systems, organizational processes, communication processes, and problem solvers. Among the materials that are very important for strengthening religious moderation in the family are tolerance, leadership in the family, division of roles in the family, equal relations between a husband and a wife, respect for the existence and quality communication of all family members, and cultivating negotiation in decision-making, And no less important is a moderate religious understanding. In terms of the Islamic law history, several families, such as the Prophet Ibrahim’s family, the Imran family (Alu Imran), and the Prophet Muhammad PBUH, can be used as examples of cultivating the true values of monotheism, humanity, social solidarity, and even purity and self-respect. Meanwhile, in Indonesia, the family of Hadaratus Sheikh KH. Hasyim Asyari, the founder of Nahdlatul Ulama can be used as an example who gives birth to children and grandchildren and even families who have a sense of nationalism, religion, humanism, pluralism and social solidarity.
PENGARUH METODE INKUIRI DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR LISTRIK STATIS DALAM PEMBELAJARAN IPA
Authors: - Sutarto - , M Damris - , - Khairinal - 
Published: April 2024

The aims of this study were to answer the following questions: (1) Is there any significant influence of applying inquiry approach on studentsâ€™ achievements in teaching static electricity? (2) Is there any significant influence of studentsâ€™ motivation on their achievements? (3) Is there any significant influence of applying inquiry approach on studentsâ€™ achievements of two groups of students owning high and low motivation? (4) Is there any interaction between inquiry approach and motivation on studentsâ€™ achievements? Two groups of students of SMPN 17 Sarolangun were taught by means of inquiry and conventional approach in studying static electricity separately. A pretest and posttest were administered by means of objective tests and studentsâ€™ motivation were measured by means of questionaire of Likert scale of 5. The study revealed that studentsâ€™ achievements of experimental groupÂ is higher than the control group. In addition, the students with high level of motivation also showed higher achievements than the students with low level of motivation. Moreover, there is no interaction between inquiry approach and learning motivation on studentsâ€™ achievements in studying static electricity. Keywords: effect of inquiry method, motivation, studentsâ€™ achievements, static electricity
Effects of kinematics and kinetics parameters of the vertical drop jump test on differences between the sexes and dominant and non-dominant feet
Authors: Sudo Daisuke , Hosokawa Masato , Maeda Yusuke 
Published: April 2024

Abstract

Study aim: This study clarified the relationship between sex and dominant and non-dominant feet during landing movements in the vertical drop jump (VDJ).

Materials and methods: The participants were 16 healthy adults (8 men, 8 women) with no orthopedic history. A three-dimensional motion analyzer and a floor reaction force meter were used for measurement. The exercise task was a VDJ in which the participants jumped from a 30-cm-high platform, and the relationship between sex, dominant leg, and non-dominant leg was compared.

Results: In terms of joint angle, the main effect of sex on the internal/external knee joint angle was observed. No significant differences were observed in the other parameters.

Conclusions: A sex difference was found in the internal/external angles of the knee joint during the landing of the VDJ from 30 cm. However, there were no differences in the kinematic and kinetic data between the dominant and non-dominant legs.
Justification of Technological and Design Parameters of Polder Drainage Systems by an Optimization Approach
Authors: Volk Pavlo , Rokochynskiy Anatoliy , Volk Liubov , Chugai Yevhen , Tykhenko Ruslan , Openko Ivan , Tykhenko Olha 
Published: April 2024

Abstract
A system optimization method was used, which consists in the consistent justification of optimal technological and constructive solutions and parameters of drainage polder systems during the development of their projects. This is done in compliance with modern economic and environmental requirements according to criteria and models for di erent levels of management decision-making over time (project, planned operation). Based on the performed relevant predictive and optimization calculations for the conditions of the real object, the following three tasks have been accomplished. (1) The optimal pump module at the stage of operation for the existing polder drainage system has been substantiated. (2) The design of the pumping unit and the parameters of its components during the reconstruction of the polder drainage system have been improved. This made it possible to reduce the load on the pumping equipment, the duration of its operation, and the cost of electricity by 20–40%, depending on the water level of the year. The improvement was carried out by the diversion of the corresponding part of the surface runo with additionally introduced gravity elements in the form of a puncture in the body of the protective dam and a siphon intake. (3) We have substantiated the optimal water regulation technology for the existing polder drainage system in modern and forecast weather and climate conditions, which will ensure the maintenance of the necessary water-air regime of the drained soils in di erent phases of the growing season of agricultural crops. This will make it possible, on demand, to increase the energy and general environmental and economic e ciency during their creation and functioning of the polder drainage system in accordance with modern changing conditions.
Optimization of food-grade bioactive compound extraction from plant sources by response surface methodology approach: A comprehensive review
Authors: Karabegoić Ivana , Stojanović Sandra Stamenković , Mančić Stojan , Đorđević Natalija , Malićanin Marko , Danilović Bojana 
Published: April 2024

Abstract
This comprehensive review delves into the extensive application of response surface methodology (RSM), a prominent mathematical and statistical technique, for modeling and optimizing the extraction of food-grade bioactive compounds from plant sources. The paper elucidates the optimization approach, covering experimental design, empirical models for response prediction, and the utilization of the desirability function for multiple response optimization. RSM provides a contemporary means to concurrently analyze and optimize various factors, presenting mathematical models for enhancing extraction processes efficiently. The review showcases RSM applications in traditional extraction techniques such as classical solvent extraction, Soxhlet extraction, and hydrodistillation, with a focus on factors like extraction time, temperature, ratio of plant material to solvent, and solvent concentration. The economic feasibility of RSM-optimized extraction processes is discussed, encompassing considerations of processing time, solvent consumption, and overall cost reduction. Critical aspects and challenges related to RSM implementation in extraction optimization are addressed, underscoring the significance of appropriate experimental design, model accuracy, and the incorporation of multiple responses for comprehensive optimization. The review concludes by emphasizing the pivotal role of RSM in guiding rational and efficient extraction processes for various valuable natural compounds from plant materials.
How do Porosity, Size and Interconnectivity of Pores Influence The Values of the Archie Equation Exponents in Carbonate and Sandy Rocks?
Authors: Batista Juliana Targino , Soares José Agnelo , Sobrinho Anne Beatrice Guedes , Moraes Nathália Amorim Lima de 
Published: April 2024

Objective: The aim of this study is to investigate the exponents of the Archie equation in order to support the evaluation of hydrocarbon or groundwater reserves through electrical resistivity measurements of subsurface rocks.

Theoretical Framework: The Archie equation describes the relationship between the electrical resistivity of a rock and its water saturation and depends on the cementation (m) and saturation (n) exponents. Several authors state that electrical resistivity and the exponents m and n depend on the size, geometry, and connectivity of the pores.

Method: This article applies the finite element method to simulate the propagation of the electric field in digital rock models and thus evaluate the Archie exponents.

Results and Discussion: Our results indicate that the relationship between these exponents and pore attributes is different for values below or above a threshold. The variables with the greatest influence on m are the porosity of macropores and their interconnectivity, as well as the volumetric fraction of the microporous phase. As for the saturation exponent, the variables with the greatest influence are the porosity of macropores and the interconnectivity of both potentially conductive domains.

Research Implications: The practical and theoretical implications of this research are discussed, providing insights into how the results can be applied or influence practices in the field of underground natural resource assessment. These implications may cover the sectors of hydrocarbon production, groundwater, geo-environmental investigations, and geotechnical studies.

Originality/Value: This study contributes to the literature by presenting an innovative method for determining the exponents of the Archie equation. The relevance and value of this research are evidenced by its high economic impact on the aforementioned sectors and by its applicability anywhere.