bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lattice Strain with Stabilized Oxygen Vacancies Boosts Ceria for Robust Alkaline Hydrogen Evolution Outperforming Benchmark Pt
Authors: Liu Xiaojing , Wei Shuaichong , Cao Shuyi , Zhang Yongguang , Xue Wei , Wang Yanji , Liu Guihua , Li Jingde 
Published: June 2024

AbstractEarth‐abundant metal oxides are usually considered as stable but catalytically inert toward hydrogen evolution reaction (HER) due to their unfavorable hydrogen intermediate adsorption performance. Herein, a heavy rare earth (Y) and transition metal (Co) dual‐doping induced lattice strain and oxygen vacancy stabilization strategy is proposed to boost CeO2 toward robust alkaline HER. The induced lattice compression and increased oxygen vacancy (Ov) concentration in CeO2 synergistically improve the water dissociation on Ov sites and sequential hydrogen adsorption at activated Ov‐neighboring sites, leading to significantly enhanced HER kinetics. Meanwhile, Y doping offers stabilization effect on Ov by its stronger Y─O bonding over Ce─O, which endows the catalyst with excellent stability. The Y,Co‐CeO2 electrocatalyst exhibits an ultra‐low HER overpotential (27 mV at 10 mA cm−2) and Tafel slope (48 mV dec−1), outperforming the benchmark Pt electrocatalyst. Moreover, the anion exchange membrane water electrolyzer incorporated with Y,Co‐CeO2 achieves excellent stability of 500 h under 600 mA cm−2. This synergistic lattice strain and oxygen vacancy stabilization strategy sheds new light on the rational development of efficient and stable oxide‐based HER electrocatalysts.
Advanced Design and Manufacturing Approaches for Structures with Enhanced Thermal Management Performance: A Review
Authors: Sun Qidong , Zhi Geng , Zhou Sheng , Dong Xu , Shen Qianye , Tao Ran , Qi Junfeng 
Published: June 2024

AbstractAdvanced design methods and manufacturing techniques are crucial for developing thermal management structures, essential for the efficient operation of complex equipment. This study provides a thorough review of design methodologies and advanced manufacturing technologies for thermal management materials and structures. It identifies key challenges and critically evaluates the integration of innovative design principles, such as biomimicry and topology optimization, into thermal management solutions. The analysis delves into the evolution of design theories and preparation techniques, with a specific focus on modern needs and research directions, particularly highlighting components fabricated using additive manufacturing and their effectiveness in meeting advanced thermal management requirements. Current research focuses on designing structures tailored to various cooling methods, including air‐cooling, liquid‐cooling, heat exchanger cooling, and heat pipe cooling. These designs utilize phase change materials, electrocaloric cooling, and thermoelectric cooling materials to achieve optimal thermal management performance. Additionally, emerging innovations like solid‐liquid mixed heat transfer and the elastocaloric effect are garnering increased interest. Enhancing the design of thermal management structures through rigorous numerical simulations is critical for improving engineering applicability. However, overcoming challenges related to the commercialization and practical utilization of these advanced structures remains a pressing need.
Engineered Graphene Material Improves the Performance of Intraneural Peripheral Nerve Electrodes
Authors: Rodríguez‐Meana Bruno , del Valle Jaume , Viana Damià , Walston Steven T. , Ria Nicola , Masvidal‐Codina Eduard , Garrido Jose A. , Navarro Xavier 
Published: June 2024

AbstractLimb neuroprostheses aim to restore motor and sensory functions in amputated or severely nerve‐injured patients. These devices use neural interfaces to record and stimulate nerve action potentials, creating a bidirectional connection with the nervous system. Most neural interfaces are based on standard metal microelectrodes. In this work, a new generation of neural interfaces which replaces metals with engineered graphene, called EGNITE, is tested. In vitro and in vivo experiments are conducted to assess EGNITE biocompatibility. In vitro tests show that EGNITE does not impact cell viability. In vivo, no significant functional decrease or harmful effects are observed. Furthermore, the foreign body reaction to the intraneural implant is similar compared to other materials previously used in neural interfaces. Regarding functionality, EGNITE devices are able to stimulate nerve fascicles, during two months of implant, producing selective muscle activation with about three times less current compared to larger microelectrodes of standard materials. CNAP elicited by electrical stimuli and ENG evoked by mechanical stimuli are recorded with high resolution but are more affected by decreased functionality over time. This work constitutes further proof that graphene‐derived materials, and specifically EGNITE, is a promising conductive material of neural electrodes for advanced neuroprostheses.
Prospects and Strategies for Single‐Crystal NCM Materials to Solve All‐Solid‐State Battery Cathode Interface Problems
Authors: Bai Xiaoyu , Xie Fang , Zhang Ziyang , Cao Minglei , Wang Qin , Wang Shiwen , Liu Chenyu , Su Xin , Lin Zhan , Cui Guanglei 
Published: June 2024

AbstractIn the ongoing quest to develop lithium‐ion batteries with superior capacity and enhanced safety, the focus has shifted toward all‐solid‐state batteries (SSBs) and nickel‐rich cathode materials. Despite their promise, these technologies face significant interface challenges, notably poor contact and low ion transport efficiency, leading to substantial stability issues. This review aims to provide a comprehensive analysis of both the advantages and the challenges associated with all‐solid‐state batteries. In addition, it discusses the benefits of single‐crystal application in SSBs, in terms of their kinetic performance, mechanical properties, and stability. The review concludes by proposing various strategies to optimize single‐crystal technologies, targeting the development of efficient nickel‐rich single‐crystal materials for use in all‐solid‐state batteries. These approaches offer the potential to address the core challenges currently faced by SSBs and pave the way for the next generation of high‐performance batteries.
A Hydridoaluminate Additive Producing a Protective Coating on Ni‐Rich Cathode Materials in Lithium‐Ion Batteries
Authors: Forero‐Saboya Juan , Moiseev Ivan A. , Vlara Marina‐Lamprini , Foix Dominique , Deschamps Michael , Abakumov Artem M. , Tarascon Jean‐Marie , Mariyappan Sathiya 
Published: June 2024

AbstractTo enhance the energy density of Li‐ion batteries, high‐capacity and high‐voltage cathode materials are needed. Recently, Ni‐rich layered oxides have attracted attention as they can offer ≈200 mAh g−1 when cycled up to 4.3 V. However, cycling these materials in their full capacity range often leads to excessive reactivity with the electrolyte, resulting in particle cracking, transition metal dissolution, and oxygen loss. In this study, the use of lithium hydridoaluminates as electrolyte additives is explored for lithium‐ion batteries based on nickel‐rich cathode materials. Being mild reducing agents, these additives act as HF scavengers, avoiding transition metal dissolution from the cathode. Additionally, their oxidation results in the formation of an Al‐rich protective layer on the cathode, which dampens the surface reactivity, preventing surface reconstruction and impedance build‐up. This study further stresses the important role of the cathode‐electrolyte interface phenomena on the capacity degradation of Ni‐rich cathode materials and provides a novel avenue for controlling this reactivity, thus extending their cycling life.
Sulfur source effects on soil, vegetation indices, biomass, and uptake in potato
Authors: Sharma Ayush K. , Sandhu Amanpreet Kaur , Sidhu Simranpreet Kaur , Riley Simon , Griffin Winniefred , de Sa Leitão Diego Arruda Huggins , Zotarelli Lincoln , Sharma Lakesh K. 
Published: June 2024

AbstractSulfur (S) is necessary for amino acid production, disease resistance, protein synthesis, and nitrogen assimilation in plants. We tested the performance of three S sources (magnesium sulfate [EPTOP], gypsum, and ammonium sulfate [AS]) at two different rates (45 and 90 kg S ha−1) on soil S availability, vegetative indices (VIs), above‐ and belowground biomass (BGB), and potato (Solanum tuberosum L.) S uptake. For VIs such as normalized difference vegetative index, normalized difference red‐edge index, and chlorophyll content, the maximum values were reported when gypsum and EPTOP were applied compared to AS. These differences were decreased later in the season. Significant interaction effects were reported among sites, sampling events, and sites and S sources for aboveground biomass (AGB). Similar trends were reported for the BGB, where the significant interaction effect was reported among the S sources and sampling event and S sources and sites. The AGB S uptake was affected due to the sites and sampling event. However, BGB S uptake was influenced by the interactive effect of S sources, sites, and sampling events. The VIs did not have a significant association between soil S concentration and AGB S uptake. It was found that the field history had a notable effect on the crop responses to variable S sources. In conclusion, applying S rates and sources has distinct responses, which depend on soil history and chemical properties, and that should be considered when making choices for S application in potatoes.
Palladium‐Catalyzed Synthesis of 1‐Alkyl‐5‐Arylpyrazoles: The Auto‐Tandem Catalysis for C−C Bond Cleavage/Heck Arylation
Authors: Fujioka Hiroki , Yasui Motohiro , Hamada Shohei , Takeda Norihiko , Kobayashi Yusuke , Furuta Takumi , Ueda Masafumi 
Published: June 2024

AbstractThe regioselective synthesis of 1‐alkyl‐5‐arylpyrazoles, which are potential drug candidates, has been difficult to achieve thus far. In this study, we developed an auto‐tandem Pd‐catalyzed C−C bond cleavage/Heck arylation of N‐cyclopropylhydrazones followed by cycloisomerization to afford diverse 1‐alkyl‐5‐arylpyrazoles. This step‐economical synthesis involves the cleavage of two C−H bonds and one C−C bond as well as the incorporation of directing groups. The identification of the reaction intermediates indicated an auto‐tandem catalytic pathway. The further transformation of products to 1,4,5‐substituted pyrazole and functional group transformations were carried out.
Amphiphilic Polymer Electrolyte Blocking Lattice Oxygen Evolution from High‐Voltage Nickel‐rich Cathodes for Ultra‐Thermal Stabile Batteries
Authors: Chen Jialiang , Lin Yan , Li Qiang , Ren Hao , Zhang Linchen , Sun Yuanyuan , Zhang Siyu , Shang Xinchao , Zhou Weidong , Wu Mingbo , Li Zhongtao 
Published: June 2024

AbstractNi‐rich cathodes have been intensively adopted in Li‐ion batteries to pursuit high energy density, which still suffering irreversible degradation at high voltage. Some unstable lattice O2− species in Ni‐rich cathodes would be oxidized to singlet oxygen 1O2 and released at high volt, which lead to irreversible phase transfer from the layered rhombohedral (R) phase to a spinel‐like (S) phase. To overcome the issue, the amphiphilic copolymers (UMA‐Fx) electrolyte were prepared by linking hydrophobic C−F side chains with hydrophilic subunits, which could self‐assemble on Ni‐rich cathode surface and convert to stable cathode–electrolyte interphase layer. Thereafter, the oxygen releasing of polymer coated cathode was obviously depressed and substituted by the Co oxidation (Co3+→Co4+) at high volt (>4.2 V), which could suppressed irreversible phase transfer and improve cycling stability. Moreover, the amphiphilic polymer electrolyte was also stable with Li anode and had high ion conductivity. Therefore, the NCM811//UMA‐F6//Li pouch cell exhibited outstanding energy density (362.97 Wh/kg) and durability (cycled 200 times at 4.7 V), which could be stalely cycled even at 120°C without short circuits or explosions.
Collective and Diverted Total Synthesis of the Strasseriolides: A Family of Macrolides Endowed with Potent Antiplasmodial and Antitrypanosomal Activity
Authors: Isak Daniel , Schwartz Leyah A. , Schulthoff Saskia , Pérez‐Moreno Guiomar , Bosch‐Navarrete Cristina , González‐Pacanowska Dolores , Fürstner Alois 
Published: June 2024

AbstractThe strasseriolide macrolides show promising in vitro and in vivo activities against P. falciparum and T. cruzi, the parasites causing malaria and Chagas disease, respectively. However, the as yet poor understanding of structure/activity relationships and the fact that one family member proved systemically toxic for unknown reasons render a more detailed assessment of these potential lead compounds difficult. To help overcome these issues, a collective total synthesis was devised. The key steps consisted of a ring closing alkyne metathesis (RCAM) reaction to forge a common macrocyclic intermediate followed by a hydroxy‐directed ruthenium catalyzed trans‐hydrostannation of the propargyl alcohol site thus formed. The resulting alkenyltin derivative served as the central node of the synthesis blueprint, which could be elaborated into the natural products themselves as well as into a set of non‐natural analogues according to the concept of diverted total synthesis. The recorded biological data confirmed the potency of the compounds and showed the lack of any noticeable cytotoxicity. The “northern” allylic alcohol subunit was recognized as an integral part of the pharmacophore, yet it provides opportunities for chemical modification.
Interpretable Data‐Driven Descriptors for Establishing the Structure‐Activity Relationship of Metal–Organic Frameworks Toward Oxygen Evolution Reaction
Authors: Zhou Jian , Xu Liangliang , Gai Huiyu , Xu Ning , Ren Zhichu , Hou Xianbiao , Chen Zongkun , Han Zhongkang , Sarker Debalaya , Levchenko Sergey V. , Huang Minghua 
Published: June 2024

AbstractThe development of readily accessible and interpretable descriptors is pivotal yet challenging in the rational design of metal–organic framework (MOF) catalysts. This study presents a straightforward and physically interpretable activity descriptor for the oxygen evolution reaction (OER), derived from a dataset of bimetallic Ni‐based MOFs. Through an artificial‐intelligence (AI) data‐mining subgroup discovery (SGD) approach, a combination of the d‐band center and number of missing electrons in eg states of Ni, as well as the first ionization energy and number of electrons in eg states of the substituents, is revealed as a gene of a superior OER catalyst. The found descriptor, obtained from the AI analysis of a dataset of MOFs containing 3–5d transition metals and 13 organic linkers, has been demonstrated to facilitate in‐depth understanding of structure–activity relationship at the molecular orbital level. The descriptor is validated experimentally for 11 Ni‐based MOFs. Combining SGD with physical insights and experimental verification, our work offers a highly efficient approach for screening MOF‐based OER catalysts, simultaneously providing comprehensive understanding of the catalytic mechanism.
Production and comprehensive characterization of PVA/chitosan transdermal composite mats loaded with bioactive curcumin; evaluation of its release kinetics, antioxidant, antimicrobial, and biocompatibility features
Authors: Ciftci Fatih , Özarslan Ali Can , Evcimen Duygulu Nilüfer 
Published: June 2024

AbstractRecently, researchers have shown increasing interest in incorporating bioactive substances with therapeutic properties into fiber‐structured mat biomaterials, which are favored as tissue scaffolds for wound healing applications. In this study, curcumin (Cur)‐loaded polyvinyl alcohol (PVA)/chitosan (CS) composite mats were produced using the electrospinning method and followed by the freeze‐drying method. Scanning electron microscope images proved the homogeneous structure of the composite mats, and Fourier transform infrared spectroscopy analysis showed that the Cur‐loaded composite mats were successfully produced. The antibacterial activity of Cur‐loaded PVA/CS composite mats was evaluated against Escherichia coli and Staphylococcus aureus, and the results showed that the antibacterial activity of the composite mats increased with the addition of Cur. Furthermore, the antioxidant test, release kinetics tests, and in vitro biocompatibility studies such as cytotoxicity, staining, and scratch assay of Cur‐loaded PVA/CS composite mats were carried out. The results showed that adding Cur enhanced the bioactivity of PVA10/CS10 composite mats. Further, the biocompatibility findings indicated that 10Cur‐PVA10/CS10 exhibited the highest viability value throughout all incubation periods compared with the other samples. Moreover, the highest rate of scratch closure on the 10Cur‐PVA/10/CS10 composite mats was observed at the end of 24 h compared with the other composite mats. These findings indicate that the Cur‐loaded PVA10/CS10 composite mats significantly positively impact cell migration and wound healing, making them a promising candidate as transdermal composite mats for tissue engineering and wound care applications.
Ultra‐Inclined Nanocolumnar ZnO Films Sputtered Using a Novel Masking Configuration Providing Controlled and Restricted Oblique Angle Deposition for Enhanced Sensing Platforms
Authors: Pelayo Garcia M. , Gibson D. , McAughey K. L. , Hughes D.A. , García Núñez C. 
Published: June 2024

AbstractOblique angle deposition (OAD) of inclined thin films is mainly performed using electron beam evaporation due to its accurate point source control over the incoming evaporated flux angle α, leading to thin films with a nanocolumnar inclination angle β. However, the utilization of magnetron sputtering (MS) with an extended source for OAD is not extensively studied and reported. This work presents a thorough analysis of ZnO inclined thin films deposited by a novel restricted DC‐reactive MS‐OAD technique. OAD‐inclined films are deposited at α ranged 60°‐88°, where incoming flux is restricted using a patented masking configuration enabling tunable control of deposited nanocolumn angular range. The described technique provides accurate control over the resulting β (99.5% reproducibility), allowing demonstrated βmaxof 47.3°, close to theoretical limits predicted for ZnO. The approach discussed here probes enhanced control of β comparable to that observed in evaporation, however using an extended source, resulting in high‐quality reproducible nanocolumnar‐inclined films. The mentioned improvements result from the exploration of operational parameters such as magnetron power, working pressure, and chamber temperature, as well as the design of the restricting configuration and substrate holders and their influence on the resulting inclined thin film crystallinity, and morphology.
Coumarin‐modified ruthenium complexes: Synthesis, characterization, and antiproliferative activity against human cancer cells
Authors: Jakopec Silvio , Hamzic Lejla F. , Bočkor Luka , Car Iris , Perić Berislav , Kirin Srećko I. , Sedić Mirela , Raić‐Malić Silvana 
Published: June 2024

AbstractAmong ruthenium complexes studied as anticancer metallodrugs, NKP‐1339, NAMI‐A, RM175, and RAPTA‐C have already entered clinical trials due to their potent antitumor activity demonstrated in preclinical studies and reduced toxicity in comparison with platinum drugs. Considering the advantages of ruthenium‐based anticancer drugs and the cytostatic activity of organometallic complexes with triazole‐ and coumarin‐derived ligands, we set out to synthesize Ru(II) complexes of coumarin‐1,2,3,‐triazole hybrids (L) with the general formula [Ru(L)(p‐cymene)(Cl)]ClO4. The molecular structure of the complex [Ru(2a)(p‐cymene)(Cl)]ClO4 (2aRu) was determined by single‐crystal X‐ray diffraction, which confirmed the coordination of the ligand to the central ruthenium(II) cation by bidentate mode of coordination. Coordination with Ru(II) resulted in the enhancement of cytostatic activity in HepG2 hepatocellular carcinoma cells and PANC‐1 pancreatic cancer cells. Coumarin derivative 2a positively regulated the expression and activity of c‐Myc and NPM1 in RKO colon carcinoma cells, while the Ru(II) half‐sandwich complex 2cRu induced downregulation of AKT and ERK signaling in PANC‐1 cells concomitant with reduced intracellular levels of reactive oxygen species. Altogether, our findings indicated that coumarin‐modified half‐sandwich Ru(II) complexes held potential as anticancer agents against gastrointestinal malignancies.
Efficient Near‐Infrared Fluorophores Based on Cyanostyrene Derivatives for Two‐Photon Fluorescence Bioimaging
Authors: Ren Xue , Liu Yanhong , Zhang Chao , Wu Zhiyuan , Shi Haotian , Zhang Xiyun , Zhang Song , Xu Bin , Tian Huimin , Tian Wenjing , Wang Yulin 
Published: June 2024

AbstractOrganic fluorescent materials with red/near‐infrared (NIR) emission are highly promising for use in biotechnology due to their exceptional advantages. However, traditional red/NIR fluorophores often exhibit weak emission at high concentrations or in an aggregated state due to the aggregate‐caused quenching effect, which severely limits their applicability in biological imaging. To address this challenge, we developed a series of cyanostyrene derivatives with aggregation‐induced emission characteristics, including 2,3‐Bis‐(4‐styryl‐phenyl)‐but‐2‐enedinitrile (DPB), 2,3‐Bis‐{4‐[2‐(4‐methoxy‐ phenyl)‐vinyl]‐phenyl}‐but‐2‐enedinitrile (DOB), 2,3‐Bis‐{4‐[2‐(4‐diphenylamino‐ phenyl)‐vinyl]‐phenyl}‐but‐2‐enedinitrile (DTB), and 2,3‐Bis‐[4‐(2‐{4‐[phenyl‐ (4‐triphenylvinyl‐phenyl)‐amino]‐phenyl}‐vinyl)‐ phenyl]‐but‐2‐enedinitrile (DTTB). Notably, these compounds exhibited intense solid state fluorescence owing to AIE effect, especially DTTB shows NIR emission with high solid state quantum efficiency (712 nm, ΦF=14.2 %). Then we prepared DTTB@PS‐PEG NPs nanoparticles by encapsulating DTTB with the amphiphilic polymer polystyrene‐polyethylene glycol (PS‐PEG). Importantly, DTTB@PS‐PEG NPs exhibited highly efficient NIR luminescence (ΦF=28.7 %) and a large two‐photon absorption cross‐section (1900 GM) under 800 nm laser excitation. The bright two‐photon fluorescence of DTTB@PS‐PEG indicated that it can be a highly promising candidate for two‐photon fluorescence probe. Therefore, this work provides valuable insights for the design of highly efficient and NIR‐emitting two‐photon fluorescent probes.
The last straw: Exploring COVID‐19 anxiety, bullying victimization, and teacher emotional violence in Chinese adolescents' perpetrators cyberbullying
Authors: Zhang Yuchi , Ding Min , Zhou Ping 
Published: June 2024

AbstractThe positive relationship between coronavirus disease 2019 (COVID‐19)‐related psychological distress and adolescents' cyberbullying behaviours has garnered attention. Although the global COVID‐19 pandemic has ended, examining adolescents' cyberbullying behaviours in the context of this disaster and revealing the potential complex interaction effects of COVID‐19 anxiety and peer and teacher factors on adolescents' cyberbullying behaviours, especially in non‐Western cultural contexts, hold inspirational value for developing more effective prevention or intervention programs for future disasters. We examined the moderation effects of bullying victimization and teachers' emotional violence (TEV) on the association between COVID‐19 anxiety and cyberbullying among adolescents in China. Data were collected from a recruited sample of 514 junior high school students in Beijing, China. Adolescent anxiety about COVID‐19 was positively correlated with cyberbullying. The moderating effects of the TEV and bullying victimization on the association between COVID‐19 anxiety and cyberbullying among adolescents were significant. The positive link between COVID‐19 anxiety and cyberbullying was stronger among adolescents with high bullying victimization and TEV. This study offers preliminary evidence on the risk of TEV and bullying victimization in the association between COVID‐19 anxiety and cyberbullying in Eastern cultures. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.