bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successes and lessons learned from a mobile health behavior intervention to reduce pain and improve health in older adults with obesity and chronic pain: a qualitative study
Authors: Brooks Amber K. , Athawale Abha , Rush Virginia , Yearout Abigail , Ford Sherri , Rejeski W. Jack , Strahley Ashley , Fanning Jason 
Published: April 2024

IntroductionChronic pain is a prevalent issue among older adults in the United States that impairs quality of life. Physical activity has emerged as a cost-effective and non-pharmacological treatment for chronic pain, offering benefits such as improved physical functioning, weight loss, and enhanced mood. However, promoting physical activity in older individuals with chronic pain is challenging, given the cyclical relationship between pain and sedentary behavior. The Mobile Intervention to Reduce Pain and Improve Health (MORPH) trial was designed as an innovative, mobile health (mHealth) supported intervention to address this issue by targeting daylong movement, weight loss, and mindfulness to manage pain in older adults with chronic multisite pain. The objective of this paper is to provide the result of a qualitative analysis conducted on post-intervention interviews with MORPH participants.MethodsAt the conclusion of the MORPH study, 14 participants were interviewed regarding their experience with the program. All interviews were conducted by phone before being transcribed and verified. A codebook of significant takeaways was created based on these accounts. Summaries were further synthesized into themes using the principles of thematic analysis.ResultsThree key themes of the MORPH intervention emerged from the qualitative interviews: MORPH technology (smart scales, Fitbit, MORPH Companion App) facilitated program adherence and accountability; MORPH intervention components (food tracking and mindfulness activities) facilitated program adherence and awareness, respectively; and, group meetings provided motivational support and accountability. Mobile health technologies, including a dedicated MORPH app, facilitated self-monitoring strategies, helped to break the cycle of old habits, and provided participants with immediate feedback on successes; however, technical issues required timely support to maintain engagement. Food tracking contributed to adherence and accountability for weight loss. Mindfulness activities increased participants’ awareness of anxiety provoking thoughts and pain triggers. Finally, social support via group meetings and connection, played a crucial role in behavior change, but participants noted consistency in the delivery medium was essential to fostering genuine connections.ConclusionOverall, the study results highlight the key considerations related to program technology, intervention components, and the value of social support that can help to guide the development of future interventions similar to MORPH.
Efficacy and safety of esketamine for pediatric gastrointestinal endoscopy: a meta-analysis and trial sequential analysis
Authors: Yu Yunfeng , Deng Juan , Tong Keke , Yin Yuman , Yu Rong , Tan Chuanchuan 
Published: April 2024

Objective:The role of esketamine in pediatric gastrointestinal endoscopy is still unclear. This study aims to evaluate the efficacy and safety of esketamine for pediatric gastrointestinal endoscopy.Methods:Clinical trials of esketamine for pediatric gastrointestinal endoscopy were searched in eight common databases, up to October 2023. These clinical trials were included in the meta-analysis and trial sequential analysis (TSA). The risk ratio (RR) and weighted mean difference (WMD) were used as the effect sizes for dichotomous variables and continuity variables, respectively. When the heterogeneity test showed I2 &lt; 50%, the fixed effects model was used for the meta-analysis and TSA; Otherwise, the random effects model was used for them.Results:In terms of efficacy endpoints, the meta-analysis showed that compared with placebo or blank, esketamine significantly decreased recovery time by 2.34 min (WMD −2.34; 95% Confidence interval [CI] −3.65, −1.02; p = 0.0005) and propofol consumption by 0.70 mg/kg (WMD −0.70; 95% CI −0.98, −0.43; p &lt; 0.00001), and increased mean heart rate by 4.77 beats/min (WMD 4.77; 95% CI 2.67, 6.87; p &lt; 0.00001) and mean arterial pressure by 3.10 mmHg (WMD 3.10; 95% CI 1.52, 4.67; p = 0.0001), while induction time and mean blood oxygen remained comparable. TSA indicated conclusive evidence for these benefits. In terms of safety endpoints, the meta-analysis revealed that esketamine significantly reduced involuntary movements by 59% (RR 0.41; 95% CI 0.22, 0.76; p = 0.005) and choking by 51% (RR 0.49; 95% CI 0.26, 0.92; p = 0.03), while significantly increasing dizziness by 98% (RR 1.98; 95% CI 1.11, 3.56; p = 0.02) and there were no significant differences in total adverse events, respiratory depression, and vomiting. TSA demonstrated conclusive evidence for involuntary movements and dizziness. Low-dose analysis showed that esketamine at ≤0.3 mg/kg significantly reduced recovery time, propofol consumption and involuntary movements, and significantly increasing mean heart rate, with no increase in dizziness. The Begg’s test (p = 0.327) and the Egger’s test (p = 0.413) indicated no significant publication bias, yet the funnel plot suggested potential publication bias.Conclusion:Esketamine is an effective adjuvant anesthesia for children undergoing gastrointestinal endoscopy. However, the general dose of esketamine may increase the risk of dizziness, which can be avoided by administering a low dose (≤0.3 mg/kg).
Voluntary wheel running reduces tumor growth and increases capillarity in the heart during doxorubicin chemotherapy in a murine model of breast cancer
Authors: Uurasmaa Tytti-Maria , Ricardo Chloé , Autio Anu , Heinonen Ilkka H. A. , Rundqvist Helene , Anttila Katja 
Published: April 2024

Introduction: The possible beneficial effects of physical activity during doxorubicin treatment of breast cancer need further investigation as many of the existing studies have been done on non-tumor-bearing models. Therefore, in this study, we aim to assess whether short-term voluntary wheel-running exercise during doxorubicin treatment of breast cancer-bearing mice could induce beneficial cardiac effects and enhance chemotherapy efficacy.Methods: Murine breast cancer I3TC cells were inoculated subcutaneously to the flank of female FVB mice (n = 16) that were divided into exercised and non-exercised groups. Two weeks later, doxorubicin treatment was started via intraperitoneal administration (5 mg/kg weekly for 3 weeks). Organs were harvested a day after the last dose.Results: The tumor volume over time was significantly different between the groups, with the exercising group having lower tumor volumes. The exercised group had increased body weight gain, tumor apoptosis, capillaries per cardiomyocytes, and cardiac lactate dehydrogenase activity compared to the unexercised group, but tumor blood vessel density and maturation and tumor and cardiac HIF1-α and VEGF-A levels did not differ from those of the non-exercised group.Discussion: We conclude that even short-term light exercise such as voluntary wheel running exercise can decrease the subcutaneous mammary tumor growth, possibly via increased tumor apoptosis. The increase in cardiac capillaries per cardiomyocytes may also have positive effects on cancer treatment outcomes.
Association between sports participation and resilience in school-attending students: a cross-sectional study
Authors: Sheng Xinxin , Liang Kaixin , Li Kai , Chi Xinli , Fan Huiying 
Published: April 2024

AimThis research sought to identify the association between sports participation and resilience in children and adolescents as a means to enhance mental health.MethodsA comprehensive survey was carried out, encompassing primary, middle, and high school students from chosen educational institutions. The analytical sample comprised 67,281 students of school age. Sports participation and resilience were evaluated using validated assessment tools, while relevant covariates, such as sex and school grade, were assessed through self-reported questionnaires. Generalized Linear Models were applied to ascertain the association between sports participation and resilience for the entire sample, and separately for subgroups divided by gender or school grade, after controlling for covariates.ResultsAmong the 67,281 school students, males constituted 51.9% of the sample. Approximately 47.1% of the entire sample reported no sports participation, and the average resilience score was 24.7. The regression model analysis revealed that, in the entire sample, increased in sports participation was linked to higher resilience scores (odds ratio [OR] for 1–3 times per month: 1.20, 95%CI: 1.16–1.24; OR for 1–2 times per week: 1.38, 95%CI: 1.33–1.43; OR for 3 times or more per week: 1.72, 95%CI: 1.65–1.79). Analyses stratified by gender and school grade indicated that sports participation was consistently associated with greater resilience.ConclusionThis study provides cross-sectional evidence supporting the positive association between sports participation and the resilience of children and adolescents, underscoring the potential of encouraging sports participation as a strategy for promoting mental health resilience. The findings presented herein should be subject to further confirmation or refutation in future research endeavors.
Female blind baseball players against gender discrimination: the “red diamonds” experience
Authors: Carretti Giuditta , Russo Pippo , Manetti Mirko , Marini Mirca 
Published: April 2024

BackgroundSport has the well-known power of improving body awareness, self-esteem, and social interaction, thus promoting quality of life and psychophysical wellbeing. Specifically referring to adapted disciplines, habitual practice often becomes an effective integration and self-efficacy booster. Among disabilities, visual impairment deeply alters body image perception, autonomy, and environmental/social interaction heavily reducing sport or leisure involvement opportunities. In particular, visually impaired women represent one of the most vulnerable categories to gender and disability discrimination. Moreover, even when congenitally sightless, they perceive social pressure of mainstream beauty ideals, mostly spread by media, comparable to their sighted peers. On these premises and the previously demonstrated psychophysical benefits of Italian blind baseball practice on this target population, the present study aimed to deepen the social and educative potentialities of such adapted sport applying a more sociological research approach.MethodsThe “red diamonds” event, namely, the first ever female blind baseball match, was the setting for the administration of our structured online survey. In detail, our survey comprised different evaluation tools such as the 18-item Psychological Well-Being Scale, the 12-item Short Form questionnaire, the Dresden Body Image questionnaire, the Rosenberg Self-Esteem Scale, and sociological model designed questions. Quality of life, psychological wellbeing, self-esteem, body image, and perceived female sport psychological violence were investigated in the whole women sample (n = 33) voluntarily adhering to the game.ResultsSurvey results revealed no statistically significant differences between visually impaired players (n = 13; mean age: 32.84 ± 12.05 years) and sighted on-field subjects (i.e., coaches, assistants, and referees; n = 20; mean age: 47.15 ± 12.31 years) in almost all the inquired variables, thus remarking the social and functional benefits of adapted sport through the “dual embodiment” and empowerment phenomenon.ConclusionsGiven that the event was inspired by and performed on the World Day against women violence, our study deepened not only the topic of disability discrimination but also the currently alarming gender-related one. In such a context, the present research might provide interesting cues for further investigations on disability and gender disparities in sports, hence spreading interest in this under-investigated field. In perspective, the “red diamonds” experience could also contribute to inspiring and progressively developing educative tools against any kind of discrimination by promoting integration and social growth through regular sports practice.
The earliest private statue of ancient Egypt. A re-examination of the statue of Hetepdief
Authors: Allan Scott J. 
Published: April 2024

La statue de Hetepdief n’a jamais été complètement publiée, ce qui a conduit à des interprétations erronées de l’inscription sur la base et de son identification. La présente étude fournit pour la première fois un dessin détaillé de cette inscription afin d’apporter une meilleure compréhension de la statue et de fournir des informations nouvelles sur la partie épigraphiée. Les caractéristiques inhabituelles de l’inscription distinguent cette statue des autres sculptures de la I re dynastie et de l’Ancien Empire. Elle inclut la seule utilisation connue d’une spatule (oiseau) comme un hiéroglyphe phonétique ainsi que des lignes de texte inversées, face à la statue plutôt qu’au spectateur, pratiques qui n’apparaissent dans aucune autre œuvre pour la période considérée. La datation proposée à partir du dernier roi mentionné, Ninetjer, fait de cette sculpture la première statue privée et le premier texte complet attesté. Bien que le nom du personnage, Hetepdief, ne puisse être clairement confirmé, son association avec le pr-dšr, l’absence de titre religieux explicite, doivent minimiser son identification en tant que prêtre.
Fabulæ Æsopiæ, non Æsopi. Recherche sur la terminologie fabulaire jusqu’à Phèdre
Authors: Cusset Sara 
Published: April 2024

This paper investigates the terminology referring to the fable in Antiquity until
Phaedrus who first drew a definite distinction between Aesop’s fables (fabulæ Æsopi) and Aesopic fables (fabulæ Æsopiæ). It tries to understand if the Phaedrian denomination marks a turning point in the history of fable ¢ making a genre out of it ¢, and to what extent this approach denotes on Phaedrus’ behalf a new generic awareness.
Les faisceaux des licteurs dans l’Ab Vrbe condita de Tite-Live : rôle politique et puissance symbolique des emblèmes du pouvoir
Authors: Cailleux Fanny 
Published: April 2024

This article shows that it is possible to study some aspects of Livy’s political message through the images used by the historian in his Ab Vrbe condita. Among these, the image of the fasces, carried by the lictors who surrounded the magistrates with imperium,
reveals an important reflection on the usurpation of power and on the sovereignty of the Roman people. Through this image, Livy’s work, inspired by the atmosphere of violence of the end of the Republic, teaches to the future leaders of Rome a lesson about what constitutes a legitimate form of power.
El desenvolvimiento de la industria textil latinoamericana en los siglos XIX y XX
Authors: Belini Claudio , Deliberali Marson Michel 
Published: April 2024

El desarrollo de la industria textil desempeñó un papel central en los procesos de industrialización a escala mundial. En América Latina, ese papel fue también de importancia y la rama textil lideró los primeros pasos de la industria manufacturera de la región, con las particularidades que tuvo el proceso de industrialización. A principios del siglo XX, en América Latina, la industria textil y de la confección ocupaba el segundo lugar después de la industria de alimentos y bebidas (Bulmer-Thomas, 2014, pp. 146-147).
En el contexto de la integración al mercado mundial como economías primario exportadoras, donde varias naciones latinoamericanas eran productoras de algodón y lana, la producción de textiles se transformó del siglo XIX con las primeras manifestaciones de una industria moderna para abastecer la demanda de los mercados domésticos en las economías más grandes de la región. A pesar del avance de la industria textil a finales del siglo XIX y principios del XX, algunos países latinoamericanos, como Argentina y Brasil, figuraban entre los principales importadores de hilados y tejidos de algodón del mundo en 1910 (Clark, 2007, p. 316), con una gran posibilidad de crecimiento para la producción industrial nacional a lo largo del siglo XX. Continuidades y rupturas, viejas y nuevas formas de organización productiva, cambios tecnológicos y políticas económicas permitieron el desarrollo de esa rama en el siglo XIX y comienzos del siglo XX en Brasil y México, y más tardíamente en la Argentina y el Uruguay.
The Importance of Optical Wavelength Data on Atmospheric Retrievals of Exoplanet Transmission Spectra
Authors: Fairman Charlotte , Wakeford Hannah R. , MacDonald Ryan J. 
Published: April 2024

Abstract
Exoplanet transmission spectra provide rich information about the chemical composition, clouds, and temperature structure of exoplanet atmospheres. Most exoplanet transmission spectra only span infrared wavelengths (≳1 μm), which can preclude crucial atmospheric information from shorter wavelengths. Here, we explore how retrieved atmospheric parameters from exoplanet transmission spectra change with the addition of optical data. From a sample of 14 giant planets with transit spectra from 0.3–4.5 μm, primarily from the Hubble and Spitzer space telescopes, we apply a free chemistry retrieval to planetary spectra for wavelength ranges of 0.3–4.5 μm, 0.6–4.5 μm, and 1.1–4.5 μm. We analyze the posterior distributions of these retrievals and perform an information content analysis, finding wavelengths below 0.6 μm are necessary to constrain cloud scattering slope parameters (

log
a

and γ) and alkali species Na and K. There is limited improvement in the constraints on the remaining atmospheric parameters. Across the population, we find that limb temperatures are retrieved colder than planetary equilibrium temperatures but have an overall good agreement with Global Circulation Models. As the JWST extends to a minimum wavelength of 0.6 μm, we demonstrate that exploration into complementing JWST observations with optical HST data is important to further our understanding of aerosol properties and alkali abundances in exoplanet atmospheres.
A Perfect Tidal Storm: HD 104067 Planetary Architecture Creating an Incandescent World
Authors: Kane Stephen R. , Fetherolf Tara , Li Zhexing , Polanski Alex S. , Howard Andrew W. , Isaacson Howard , Močnik Teo , Welter Sadie G. 
Published: April 2024

Abstract
The discovery of planetary systems beyond the solar system has revealed a diversity of architectures, most of which differ significantly from our system. The initial detection of an exoplanet is often followed by subsequent discoveries within the same system as observations continue, measurement precision is improved, or additional techniques are employed. The HD 104067 system is known to consist of a bright K-dwarf host star and a giant planet in a ∼55 days period eccentric orbit. Here we report the discovery of an additional planet within the HD 104067 system, detected through the combined analysis of radial velocity (RV) data from the High Resolution Echelle Spectrometer and High Accuracy Radial velocity Planet Searcher instruments. The new planet has a mass similar to Uranus and is in an eccentric ∼14 days orbit. Our injection-recovery analysis of the RV data exclude Saturn-mass and Jupiter-mass planets out to 3 au and 8 au, respectively. We further present Transiting Exoplanet Survey Satellite observations that reveal a terrestrial planet candidate (R

p
= 1.30 ± 0.12 R
⊕) in a ∼2.2 days period orbit. Our dynamical analysis of the three planet model shows that the two outer planets produce significant eccentricity excitation of the inner planet, resulting in tidally induced surface temperatures as high as ∼2600 K for an emissivity of unity. The terrestrial planet candidate may therefore be caught in a tidal storm, potentially resulting in its surface radiating at optical wavelengths.
Probing Turbulent Scattering Effects on Suprathermal Electrons in the Solar Wind: Modeling, Observations, and Implications
Authors: Zaslavsky Arnaud , Kasper Justin C. , Kontar Eduard P. , Larson Davin E. , Maksimovic Milan , Marques José M. D. C. , Nicolaou Georgios , Owen Christopher J. , Romeo Orlando , Whittlesey Phyllis L. 
Published: April 2024

Abstract
This study explores the impact of a turbulent scattering mechanism, akin to those influencing solar and galactic cosmic rays propagating in the interplanetary medium, on the population of suprathermal electrons in the solar wind. We employ a Fokker–Planck equation to model the radial evolution of electron pitch angle distributions under the action of magnetic focusing, which moves the electrons away from isotropy, and of a diffusion process that tends to bring them back to it. We compare the steady-state solutions of this Fokker–Planck equation with data obtained from the Solar Orbiter and Parker Solar Probe missions and find a remarkable agreement, varying the turbulent mean free path as the sole free parameter in our model. The obtained mean free paths are of the order of the astronomical unit, and display weak dependence on electron energy within the 100 eV–1 keV range. This value is notably lower than Coulomb collision estimates but aligns well with observed mean free paths of low-rigidity solar energetic particle events. The strong agreement between our model and observations leads us to conclude that the hypothesis of turbulent scattering at work on electrons at all heliospheric distances is justified. We discuss several implications, notably the existence of a low Knudsen number region at large distances from the Sun, which offers a natural explanation for the presence of an isotropic “halo” component at all distances from the Sun—electrons being isotropized in this distant region before traveling back into the inner part of the interplanetary medium.
The First Spatially Resolved Detection of 13CN in a Protoplanetary Disk and Evidence for Complex Carbon Isotope Fractionation
Authors: Yoshida Tomohiro C. , Nomura Hideko , Furuya Kenji , Teague Richard , Law Charles J. , Tsukagoshi Takashi , Lee Seokho , Rab Christian , Öberg Karin I. , Loomis Ryan A. 
Published: April 2024

Abstract
Recent measurements of carbon isotope ratios in both protoplanetary disks and exoplanet atmospheres have suggested a possible transfer of significant carbon isotope fractionation from disks to planets. For a clearer understanding of the isotopic link between disks and planets, it is important to measure the carbon isotope ratios in various species. In this paper, we present a detection of the 13CN N = 2 − 1 hyperfine lines in the TW Hya disk with the Atacama Large Millimeter/submillimeter Array. This is the first spatially resolved detection of 13CN in disks, which enables us to measure the spatially resolved 12CN/13CN ratio for the first time. We conducted nonlocal thermal equilibrium modeling of the 13CN lines in conjunction with previously observed 12CN lines to derive the kinetic temperature, H2 volume density, and column densities of 12CN and 13CN. The H2 volume density is found to range between (4 − 10) × 107 cm−3, suggesting that CN molecules mainly reside in the disk's upper layer. The 12CN/13CN ratio is measured to be

70

−
6

+
9

at 30 < r < 80 au from the central star, which is similar to the 12C/13C ratio in the interstellar medium. However, this value differs from the previously reported values found for other carbon-bearing molecules (CO and HCN) in the TW Hya disk. This could be self-consistently explained by different emission layer heights for different molecules combined with preferential sequestration of 12C into the solid phase toward the disk midplane. This study reveals the complexity of the carbon isotope fractionation operating in disks.