bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mid‐trimester Acute Polyhydramnios and Fetal Sacro‐coccygeal Teratoma
Authors: Conaghan C. J. , MacLean A. B. , Duff G. B. , Bashford D. H. , Hunter Lauree A. 
Published: August 2010

AbstractA 31 year old patient presented in mid‐trimester with acute polyhydramnios and ankle oedema. Ultrasonography suggested a sacro‐coccygeal teratoma. Spontaneous abortion occurred and the diagnosis was confirmed.
Ethnic Birth Patterns and Fetal Outcome in Auckland and New Zealand in the 1970's and Their Medico‐social Implications: Part II Ethnicity and Medico‐Social Implications
Authors: Hutchison C. P. T. 
Published: August 2010

AbstractMaoris and New Zealand Pacific Islanders are steadily forming a larger portion of New Zealand̂s population. The purpose of this paper is to explore possible ethnic medico‐social disadvantages and propose remedial action. It appears Maoris and Pacific Islanders are disadvantaged in terms of health, education, employment/occupation, income and legal offending.In general, socio‐economic status, rather than ethnicity is the important factor in terms of health outcome. This paper proposes that health priorities be concentrated in the first five years of life and special effort must be directed towards the lower socio‐economic groups. Mechanisms to allow this are discussed.
Determinant Factors in Foetal Mortality Associated with Umbilical Cord Prolapse
Authors: Orhue Augustine A. E. , Unuigbe Jacob A. 
Published: August 2010

AbstractFifty cases of umbilical cord prolapse in a nine‐year period is analysed. The incidence was 0.21% and foetal mortality rate 28%. The Caesarian section rate was 86% and all live babies were delivered by Caesarian section.Analysis of the foetal mortalities revealed the following trend. Of the 18 patients who ruptured membranes spontaneously at home, foetal mortality was 66.6% as against 6.3% for those rupturing membranes in hospital. Of the 20 patients arriving hospital over two hours after the cord prolapse, 65% foetal mortality occurred. When the diagnosis delivery interval was beyond 30 minutes the foetal mortality for the 19 cases was 68.4%. Of the 19 cases where cord prolapse occurred with the Os uteri 8–10 centimeters dilated and had attempted vaginal delivery before Caesarian section, the foetal mortality was 57.9% as against 9.7% for the 31 cases where cord prolapse occurred with the Os uteri less than seven centimeters dilated and had a straight Caesarian section. Other contributing factors to foetal mortality were missed diagnosis of cord prolapse on admission, wrong judgement of the safest mode of delivery and undue delay of patient arrival in labour ward after cord prolapse.
Lack of HLA (A, B and C) Antigen Expression on the Cell Surface of Trophoblastic Tumors (Hydatidiform Moles and Choriocarcinoma)
Authors: Yamashita Kohki , Mure Kazuhide , Hayashi Hiroaki , Sagawa Tadashi , Ishikawa Mutsuo , Shimizu Tetsuya , Yoshiki Takashi 
Published: August 2010

AbstractTwo hydatidiform moles and a choriocarcinoma as well as three normal chorionic villi (control) were examined by an immunofluorescence method in order to investigate the expression of HLA (A, B and C) antigens on trophoblastic tumor cells.In the hydatidiform moles, HLA antigens were absent from trophoblastic cells of the molar villus, but present on cells in villous stroma in a manner similar to those in normal chorionic villus. In the choriocarcinoma, HLA antigens were virtually negative.These findings are consistent with a hypothesis that trophoblastic tumor does not express HLA antigens.
Fibrin Related Antigen: An Aid in Cytologically False Negative Effusion Fluid
Authors: Crandon Alex J. , Singh Pritam 
Published: August 2010

AbstractIn this study of F.R.Ag. levels in effusion fluid from 99 patients, it was found that the levels were higher in those patients with malignant disease (mode equals 1,024 mg/1) compared with patients with benign disease (mode equals 8 mg/1).Estimation of F.R.Ag. levels in effusion fluid using a simple inexpensive, commercial kit would appear to be of adjuvant value in assessing the nature of an effusion.
Uterine Cervical Cancer Associated with Eosinophilic Infiltration
Authors: Yang Li‐Chung , Lee Mu‐Soon , Tsai Chung‐Liang , Chang Chung‐Chuan , Lin Yun‐Nan , Hsu Chien‐Tien 
Published: August 2010

AbstractIn the past five years, 5 out of 999 cases of uterine cervical cancer (0.5%) were found to be associated with eosinophilia in the peripheral blood, the tumor itself and the regional lymph nodes irrespective of whether they were metastatic or non‐metastatic. In all five cases peripheral eosinophilia coincided with tumor eosinophilia. In four cases, no metastases were observed and eosinophilia came down to the normal range after operation. The patients are still living and well. In one case in which extensive node metastases and parametrial invasion were confirmed, eosinophilia remained abnormally high after the operation and the patient died in 2 years. Unlike the findings in the literature, our small series did not confirm a close link between peripheral eosinophilia and dissemination of malignancy but rather between both eosinophilia's. Our limited experience with this small series suggests that peripheral blood eosinophilia and tumor eosinophilia are not significant indicators for prognostication of malignancies as reports in the literature emphasize, but they can be used as a good tumor marker monitoring the progress or regress of malignancies when other causative factors for eosinophilia can be definitely excluded.
Localization OF HCGα and HCGβ in Trophoblastic Tumors
Authors: Kawagoe Koh , Mori Shigeo 
Published: August 2010

AbstractTissue distribution of the subunits of human chorionic gonadotropin (hCG), hCGα and hCGβ, in eight cases of trophoblastic tumors, including four cases of choriocarcinoma, two cases of invasive mole and two cases of hydatidiform mole, was studied by the immunoperoxidase method. In villous trophoblasts of hydatidiform mole, though distribution patterns in the cytoplasm differed, both hCGα and hCGβ were revealed to be located chiefly in the syncytiotrophoblast and to a lesser extent in the cytotrophoblast suggesting that hCG is not only localized but also synthesized mainly in the syncytiotrophoblast while the immature cytotrophoblast does not produce hCG. In invasive mole, villi were markedly degenerative, composed mostly of the syncytiotrophoblast with scarce intraplasmic hCGα. This condition of the villi is considered to be the result of intensive chemotherapy prior to operation, and may be explained by the so‐called cellular effect of transient increase of hCG in the serum during chemotherapy. In choriocarcinoma, strongly immunoreactive products of hCGα and hCGβ were observed in the syncytiotrophoblast‐like cells with several nuclei scattered like islands in the invading front. These findings are considered to be related to the local immunosuppressive effect of hCG on invasion and survival of choriocarcinoma cells analogous to the syncytiotrophoblast in the trophoblastic shell and column of normal pregnancy.
Foeto‐maternal Outcome following Vacuum Extraction:Recent Experience with 625 Consecutive Cases
Authors: Orhue Augustine A.E. 
Published: August 2010

AbstractSix hundred and twenty five consecutive vacuum extractions in an eight years period is reviewed. The overall success rate was 97 percent and 21.4 percent were done in the first stage of labour. The occurrence of a vesico‐vaginal fistula in 0.16% of cases is emphasised as a very serious maternal complications. The corrected perinatal mortality rate was 1.7% and major foetal scalp lesion occurred in 4.8% of cases.The vacuum extractor is presented as a safe instrument for use especially when positional problems are present in the shallow African pelvis. Extra care and experience is required for vacuum extraction in the first stage of labour especially with the extreme perineal muscle laxity in the grandmultipara in order to avoid serious damage to maternal tissues.Careful choice of patients and adherence to the principles of vacuum cup application and traction techniques are emphasised in order to reduce the incidence of foeto‐maternal complications.
Dose–response Relationship between Dose of Clomiphene Citrate and Incidence of Ovulation
Authors: Seki Katsuyoshi , Kato Koichi 
Published: August 2010

AbstractOne hundred and fifty anovulatory, infertile women were treated with clomiphene citrate in an individualized, graduated therapeutic regimen. Women with high serum follicle stimulating hormone or prolactin concentrations were not included. Ovulation was induced in 135 (90.0%) of the 150 women. Of the 55 women who achieved pregnancy, 50 (90.9%) did so at a dose of 150 mg for 5 days or less. Five pregnancies (9.1%) were achieved with higher doses. There was a significant correlation between the total dose of clomiphene citrate administered per cycle and the cumulative incidence of ovulation. There was also a significant relationship between the total dose of clomiphene per cycle and the cumulative incidence of pregnancy.
Mid‐pregnancy Amniocentesis
Authors: Ju Kap Soon , Lee Sun Kyung , Kim Seung Bo , Lee Jae Hyun 
Published: August 2010

AbstractThe follow‐up study on the outcome of mid‐pregnancy performed amniocentesis with or without ultrasound guidance is carried out from a total of 913 cases.The results are as follows;

Out of 473 pregnancy without ultrasound guidance and 440 with ultrasound guidance, there were observed full term deliveries in 457 (96.6%) and 419 (95.2%), premature deliveries in 8 (1.69%) and 12 (2.72%), immature deliveries in 2 (0.4%) and 3 (0.68%), spontaneous abortions in 3 (0.63%) and 0, and induced abortions in 3 (0.6%) and 6 (1.36%) respectively.
The perinatal mortality was 27.48 in cases of amniocentesis without ultrasound guidance and 13.63 in cases of amniocentesis with ultrasound guidance.
The 0.03 percent of the pregnant women having amniocentesis without ultrasound guidance had spontaneous abortions from 10 to 60 days after amniocentesis. No abortions from the cases with ultrasound guidance was observed.
A total of 9 cases had induced abortion. Seven cases were prenatally diagnosed fetal anomalies. Six were chromosomal anomalies and one anencephalic fetus.
No specific infant diseases were observed and the upper respiratory infections were the most common disease from both groups. An infant died of pneumonia in each group.
Out of a total of 913 pregnancies, 12 cases (1.3%) showed anomalies. Only 5 cases gave births and 2 of them, a cleft palate and a Polydactyly were survived.
The 29 cases (6%) out of 473 cases without ultrasound guidance and the 74 cases (16.8%) out of 440 cases with ultrasound guidance complained after amniocetesis such as abdominal pain in most, amniotic leakage and vaginal spotting. One case with amniotic fluid leakage wanted to be aborted, and two with vaginal spotting were turned out to be placenta previa and hydatidiform mole.
Complications of Laparoscopy
Authors: Patel Dina N. , Parikh Mahendra N. , Nanavati Murai S. , Jussawalla Mehernosh J. 
Published: August 2010

AbstractThis study presents the analysis of 8,600 cases of laparoscopy both diagnostic and operative carried out by the Nowrosjee Wadia Maternity Hospital and Post Graduate Institute, Bombay. Of these, 2,300 cases were performed at the hospital and 6,300 cases at various camps all over India. Variety of complications noted in these cases have been evaluated.
Diagnostic Colposcopy in Adenocarcinoma of the Uterine Cervix
Authors: Ueki Minoru , Maeda Takayoshi , Sano Takashi , Sugimoto Osamu 
Published: August 2010

AbstractAlthough the incidence of adenocarcinoma of the cervix is 5% or more of all cases of cervical carcinoma, colposcopical studies of this lesion have never been reported systematically. We observed the colposcopic findings in 52 cases of cervical adenocarcinoma. The findings of cervical adenocarcinoma on colposcopy and of endometrial carcinoma on hysteroscopy were compared to confirm the diagnosis.In the early stages of cervical adenocarcinoma, papillary findings, transformation zone‐like findings, a combination of these findings, granulation‐like findings, and atypical vessels were observed. The lesions tended to bleed and secrete mucus, and root‐like, wastethread‐like, glomerular, tendril‐like and corkscrew‐like vessels were seen. In advanced stages, the lesion tended to be a necrotic mass with a collapsed surface. In some adenosquamous carcinomas, white epithelium, mosaic, and punctation were observed, but these were not seen in true adenocarcinomas.These surface and capillary characteristics resemble the hysteroscopic findings of endometrial carcinoma.
Menstrual Disorders in Adolescence
Authors: Mukherji Joydev , Chowdhury N.N. Roy 
Published: August 2010

AbstractOf 380 adolescents who attended Eden Hospital, Calcutta Medical College, India, over a 9 month period, 215 had some menstrual problem. There were 75 cases with primary amenorrhoea, 28 with secondary amenorrhoea, 42 with oligomenorr‐hoea, and 70 with excessive bleeding.Primary amenorrhoea stood out as the commonest serious disorder. Leaving aside delayed menarche, majority of its causes including Mullerian Tract abnormalities, Gonadal dysgenesis and chromosomal aberrations are determined in utero. These require only modest skill for diagnosis and are mostly absolute barriers to fertility.Secondary amenorrhoea although potentially less serious requires more investigations. Nutritional disturbances, polycystic ovarian disease, and genital tuberculosis are important causes.Oligomenorrhoea', commoner than secondary amenorrhoea may be paraphysi‐ological during early adolescence. However severe oligomenorrhoea may have causes similar to secondary amenorrhoea.Puberty menorrhagia is the commonest cause for emergency hospital admission in teenagers. Although most cases are dysfunctional, the organic causes should be carefully excluded.
Ultrasonic Evaluation and Classification of Ovarian Tumors
Authors: Vera Ma. Trinidad R. , Okai Takashi , Mukubo Masaaki , Kozuma Shiro , Maeda Tsukio , Mizuno Masahiko 
Published: August 2010

AbstractEcho pattern classification for ovarian tumors was devised to evaluate ovarian tumors pre‐operatively, distinguishing malignant ones from the benign tumor. The study covered a period of 8 years, for which 182 cases of ovarian tumor were initially evaluated to devise and test the classification, after which another set of 198 cases diagnosed as ovarian tumor by ultrasound was studied to determine its use in the clinics. The classification consisted of 6 patterns and 2 or 3 sub‐groups for each pattern. The probability of the tumor to be benign was high if it fell in patterns I, II, III, and IV‐A and to be malignant if it fell in patterns IV‐B, V, and VI. The percentage of accuracy of diagnosing malignant ovarian tumor was 89.36% with a low rate (0.65%) of false negative diagnosis. Histologic and echo pattern correlation was high. The results suggest the usefulness of the classification in clinical setting.
Demonstration of Immunoreactive LHRH in the Human Ovaries by Peroxidase Immunocytochemistry
Authors: Huang Hung June , Ishimaru Tadayuki , Yamabe Tooru 
Published: August 2010

AbstractThe distribution of immunoreactive LHRH in the human ovary was examined using paraffin sections by peroxidase immunocytochemistry. Immunoreactive LHRH is seen in the granulosa cells of mature follicles, and in the theca interna cells of atretic follicles. But the immunoreactive LHRH is not found in the theca interna cells or stromal components of mature follicles, and in the granulosa cells or stromal components of atretic follicles. There may be a possibility that immunoreactive LHRH serves as a paracrine modulator in follicular maturation.
Lung Surfactant Apoprotein and Phosphatidylglycerol in Amniotic Fluid for Prediction of Respiratory Distress Syndrome
Authors: Dhall Kamala , Majumdar Sidhartha , Narang Anil , Rupinder Raj 
Published: August 2010

AbstractThe proteins (Apoproteins) of adult human lung surface active material were separated by Sephadex G‐200 gel chromatography into four components. Fraction IV showed heterogeneity of three different proteins by disc gel electrophoresis and other fractions provided single proteins.Immunochemical analysis suggested that the protein of fraction II appeared in the lung tissue of neonate and adult whereas the proteins of fraction IV appeared in only adult lung tissue and of fraction I was present in lung tissue of prematue baby, neonate and adult. Since the protein of fraction II appeared in neonatal lung tissue and was the major component of lung surfactant active material, this protein in amniotic fluid was immunoassayed semiquantitatively to predict the fetal lung maturation in normal and abnormal pregnancy. Using a scoring system for the concentration of this protein in amniotic fluid, fetal lung immaturity was predicted in two cases which later on developed respiratory distress syndrome.The results of lung apoprotein were statistically compared with PG values and L/S ratio carried out in the same amniotic fluid samples.
A Case of Pelvic Arteriovenous Fistula
Authors: Kigawa Junzo , Makio Akira , Torii Yuuichi , Narita Kiyoji , Aoki Satoru 
Published: August 2010

AbstractArteriovenous fistulas in the female pelvis are rare, except in intrautenne cirsoid aneurysma. There are only two cases, including this case, of A‐V fistulas which become evident during the postpartum period in the literature. The patient began to experience left abdominal pain in 6th month after childbirth and an A‐V fistula between the left internal iliac artery and vein was detected by arteriography. Ligature of the left internal artery and left paravaginal vein was followed by an uneventful postoperative course.
In vitro Fertilization Applied for Tubal and Non‐Tubal Causes of Infertility
Authors: Yovich John L. , Yovich Jeanne M. , Tuvik Ann I , Junk Stephen , Bootsma Barbara , PhD Phillip L. Matson 
Published: August 2010

AbstractA combined service and research program of IVF‐ET was established at PIVET Laboratory, Perth, Western Australia in 1981. By May 1985, 592 couples have had a mean of 1.66 treatment cycles with a total of 140 pregnancies achieved (23.7% per couple). The earliest cases were treated for occlusive tubal disease, but increasingly, a wide range of infertility disorders have been managed by IVF‐ET. The pregnancy rate achieved for tubal disease was 23.3%. Rates are significantly lower in women with endometriosis (9.1%; p<0.01) and significantly higher where the woman has no recognizable factor (including those treated for failed artificial insemination by donor semen) and those with circulating antispermatozoal antibodies (up to 47.6%; p<0.001). With regard to male factors, applying the treatment methods described, pregnancy rates did not vary between groups (mean 23.7%) although donor semen was used where an insufficient number of motile spermatozoa was obtained from husband's semen.
Characteristics of Anticellular Activities of Human Recombinant Interferon γ on Gynecological Malignancies: In vitro Sensitivity
Authors: Iwasaka Tsuyoshi , Yoshimura Takahiro , Sugimori Hajime 
Published: August 2010

AbstractThe anticellular activity of recombinant human interferon γ (RelFN‐γ) against cultured human cell lines established from gynecological malignancies was compared with that of natural human fibroblast interferon‐β (IFN‐β) and the in vitro anticellular action of RelFN‐γ was characterized. The anticellular spectrum of ReIFN‐γ' against 8 gynecological cancer cell lines was basically similar to that of IFN‐β, though RelFN‐γ was more effective in inhibiting the growth of these cell lines. It was also revealed that the inhibitory activity against cell growth induced by ReIFN‐γ was relatively long‐lasting and stable, and that RelFN‐γ but not IFN‐β had cytotoxic activity.
Diagnostic Laparoscopy in Gynecologic Disorders
Authors: Chang Yoon Seok , Lee Jin Yong , Moon Shin Yong , Kim Jung Gu 
Published: August 2010

AbstractA clinical analysis of 3015 consecutive cases of diagnostic laparoscopy performed from June 1974 to May 1985 was done. Infertility was the leading indication (68.1%). The pelvic abnormalities were found in 84.5% of 2053 infertile patients. Tubal occlusion and pelvic adhesion were the most common abnormalities. With regard to the tubal patency, there was agreement between laparoscopic and hysterosalpingographic findings in 77.5% of 1267 infertile patients. In 54.5% of 244 patients with suspected ectopic pregnancy, the diagnosis was confirmed. The error in prelaparoscopic diagnosis of obscure pelvic mass was 31% and unwarranted surgery was avoided in 18.3% following laparoscopy.
Catheterization of Urinary Bladder before Major Gynaecological Surgery
Authors: Malik Lala Rukh 
Published: August 2010

AbstractBetween 1979 and 1983, 1,292 cases who underwent major gynaecological operations in the Department of Obstetrics and Gynaecology, Khyber Hospital, Peshawar, were studied. One group (777 cases) had catheterization of bladder whereas the other group (515 cases) emptied their bladders immediately before anaesthesia and were not catheterized. There was no significant difference in the number of cases of retention of urine and bladder injury between the 2 groups except that in cases of laparotomy there were significantly fewer cases of retention in the non‐catheterized patients (P = 0.05).
Intrauterine Growth Retardation: A Comparative Study of the Perinatal Outcome
Authors: Nagarkatti Rajendra S. , Pandit R. D. 
Published: August 2010

AbstractA comparative study of the perinatal outcome, in 60 cases of intrauterine growth retardation (I.U.G.R.) which were antenatally monitored through clinical examinations and investigations, as against 60 cases which were not diagnosed and therefore remained unmonitored, was carried out. Besides epidemiological characteristics like age and parity, special attention was paid to antenatal care received by both groups, etiological factors involved, the time and method of diagnosis and the special investigations used. Only 18% in the unmonitored group, as compared to 33% in the monitored group required operative interference during delivery. The incidence of macerated and fresh stillbirths was 4 times more in the unmonitored group. The incidence of neonatal complications and neonatal deaths also showed a threefold increase in the unmonitored group. Only 53% in the unmonitored group as compared to 90% in the monitored group had a successful perinatal outcome, aptly depicting the value of prompt diagnosis and management of I.U.G.R.
Properties of Ectopic Proteins Synthesis in vitro by Human Cervical Carcinoma Cells
Authors: Chao Kuan‐Chong , Ng Heung‐Tat , Chang Chi‐Ching , Hu Cheng‐Po , Chang Chung‐Ming 
Published: August 2010

AbstractTwo ectopic proteins, carcinoembryonic antigen (CEA) and ferritin, were synthesized in the culture media from a newly established cervical cancer cell line as measured by radioimmunoassay. The cervical cancer cell line, designated CC‐7T, produced CEA and ferritin ectopically in vitro in increasing quantities as cultures proceeded. In control studies, cultured fibroblasts did not have this secreting phenomenon. The amount of CEA and ferritin production by CC‐7T cells depended upon the cell density, nutrient availability, and the accumulation of waste products. Our findings indicate that CEA and ferritin were directly secreted by cervical cancer cells from cell line CC‐7T. This cell line should be a useful tool for studies of the mechanism of re‐expression of the oncodevelopmental genes which are responsible for the proteins' production. We also presume that there is a parallelism between the ectopic protein production and the advancement of the tumor process in positive cervical cancer patients making them excellent tumor markers for clinical monitoring of patients.