bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smart Self‐Healing Bituminous Material Modified by Shape Memory Polymer of Polynorbornene
Authors: Shao Rong‐Yue , Xing Qin‐Yu , Wang Xin‐Yu , Su Jun‐Feng 
Published: February 2025

ABSTRACTShape memory polymers can be used to improve the self‐healing capability of materials. The aim of this work is to investigate the physicochemical characteristics and self‐healing capability of bituminous material blending with the shape memory polymer of polynorbornene. FT‐IR results indicated the presence of chemical links between functional groups between polynorbornene and bitumen. The ultrathin slice SEM image of the blend showed that polynorbornene and bitumen were compatible. The DSC curve of the blend sample only had one absorption peak, indicating their partially compatibility. The blending of polynorbornene dramatically increases bitumen's thermal stability, raising the bitumen blend's decomposition temperature to 320°C. The tensile strength of the blends at the same temperature also increases sharply. The change results in physical parameters indicated that the polynorbornene addition had increased the hardness and thermal stability of the blends. Rheological tests also demonstrated that adding the polynorbornene significantly increased the complex shear modulus (G*) values of blend samples, indicating that under the same temperature conditions, the polynorbornene significantly improved the deformation resistance of bitumen. The test results of deformation recovery capability indicated that the blends possessed rapid shape memory function. The excellent shape memory function of polynorbornene endowed bitumen with a multi‐self‐healing capability enhancement.
SDP‐based analysis and control of the response peak of discrete‐time uncertain systems via head/tail partition
Authors: Chesi Graziano , Shen Tiantian 
Published: February 2025

ABSTRACTThis paper addresses the problems of analyzing and controlling the response peak of a discrete‐time uncertain linear system. A novel approach is proposed for the analysis problem based on the solution of a semidefinite program (SDP). The novel idea consists of splitting the response into two temporal parts, head and tail, which are analyzed via inspection of the response formula and via quadratic Lyapunov functions polynomially parameterized by the uncertainty. This approach is extended to deal with the control problem by proposing two strategies, one based on a nonconvex search obtained by alternately freezing some decision variables and the other one based on a convex search obtained by constructing a controller‐dependent index. The proposed approach has key advantages with respect to the existing methods, which may be conservative, or inapplicable, or computationally prohibitive.
Tube‐based stochastic model predictive control leveraging Gaussian process regression for linear systems with bounded additive uncertainties
Authors: Li Fei , Wu Chao , Cui Fangyin , Li Jianfeng , Duan Xiaoming , Song Lijun , Ji Xuande 
Published: February 2025

AbstractThis paper presents an adaptive tube‐based stochastic model predictive control algorithm for linear systems with state‐dependent additive uncertainties. Specifically, the uncertainty of the system is modeled using Gaussian process regression, and the information predicted by Gaussian process regression online is leveraged to establish a confidence region for the uncertainty. By employing this confidence region, the time‐varying probabilistic reachable set, referred to as a tube, is computed. Subsequently, the Gaussian process‐based stochastic model predictive control algorithm is devised by employing the probabilistic reachable set to redefine the state constraint. Furthermore, the recursive feasibility of the algorithm and the stability of the closed‐loop system are proved. Finally, the effectiveness and superiority over existing methods are validated by numerical simulations.
Gedanken zum Planen und Erhalten von Bauwerken
Authors: Kreuzinger Heinrich 
Published: February 2025

AbstractIn diesem Beitrag werden stichpunktartig einige wesentliche Aspekte der Arbeit von Professor Stefan Winter an der Technischen Universität München unter dem Leitgedanken „Bauwerke planen und erhalten“ genannt. Ziel aller am Bau Beteiligten ist es, Bauwerke so zu entwerfen, dass sie sicher, langlebig und wirtschaftlich sind und die Umwelt möglichst wenig belasten. Insbesondere der Baustoff Holz kann hier einen wertvollen Beitrag leisten. Voraussetzungen dafür sind eine fundierte Ausbildung der Ingenieure, klare Normen und Zulassungen, zuverlässige Prüfung der Unterlagen und Baustoffe sowie die regelmäßige Wartung bestehender Bauwerke. Professor Stefan Winter hat mit seinem Engagement als Bauingenieur und Hochschullehrer entscheidend zur Erreichung dieser Ziele beigetragen.
Von smartBRIDGE Hamburg zum Digitalen Zwilling Haupthafenroute im Hamburger Hafen
Authors: Schwarz Niklas , Petersen‐Tulipan Matthias 
Published: February 2025

AbstractEine hochwertige und leistungsfähige Infrastruktur ist das Rückgrat einer gut funktionierenden Volkswirtschaft. Um diesem Anspruch gerecht zu werden, stehen die Betreiber der Infrastruktur in Deutschland vor großen Herausforderungen. Eine alternde Infrastruktur trifft auf stark wachsende Verkehrsbelastungen. Gleichzeitig ist lt. dem UN Global Status Report for Buildings and Construction 2020 die Baubranche verantwortlich für ca. 40 % der globalen CO2‐Emissionen. In Zeiten des bevorstehenden Klimawandels steigt der Druck, Infrastruktur nachhaltig und umweltschonend zu erhalten. Ein valider Ansatz, um Verbesserungspotenziale zu heben, ist die Nutzung digitaler Technologien und effizienter Arbeitsmethoden. Der folgende Beitrag beschäftigt sich mit dem Einsatz von Digitalen Zwillingen von Infrastrukturbauwerken in der Hamburg Port Authority (HPA). Zuerst wird smartBRIDGE Hamburg vorgestellt – der Digitale Zwilling der Köhlbrandbrücke. smartBRIDGE Hamburg zeigt das Potenzial eines digitalen Erhaltungsmanagements und generiert einen objektiven Bauwerkszustand mithilfe analoger und digitaler Daten. Basierend auf diesen Erfahrungen hat ein interdisziplinäres Autor:innen‐Team, bestehend aus dem Bundesministerium für Digitales und Verkehr (BMDV), BIM.Hamburg und Marx Krontal Partner, den Beitrag „Digitaler Zwilling von Brücken: Beitrag zum Masterplan Digitaler Zwilling Bundesfernstraßen“ verfasst. Zusätzlich zum Beitrag wird ein Reallabor zur Verfügung gestellt, welches das Prinzip Digitaler Zwilling erlebbar macht. Im Januar 2024 hat Bundesminister Dr. Volker Wissing das Reallabor und den Beitrag veröffentlicht. Als Fortsetzung der guten Kooperation zwischen BMDV und BIM.Hamburg wird in der HPA der Digitale Zwilling der Hamburger Haupthafenroute entwickelt.
Tracing interpersonal emotion regulation, behavioural emotion regulation strategies, hopelessness and vocabulary retention within Bing vs. ChatGPT environments
Authors: Wang Meiping , Akhter Shamim 
Published: February 2025

AbstractDespite the growing integration of artificial intelligence (AI) in language education, limited research has explored its impact on emotional regulation and vocabulary retention, particularly in English as a foreign language (EFL) contexts. This study addressed this gap by comparing the effects of Bing and ChatGPT environments on interpersonal emotion regulation (IER), behavioural emotion regulation strategies (BERS), hopelessness and vocabulary retention among 458 upper‐intermediate Chinese EFL learners. Participants were divided into three groups: Bing, ChatGPT and a control group (CG) receiving traditional instruction. Both AI‐supported groups engaged with identical content and tasks on their respective platforms, while the CG followed a conventional curriculum. A mixed‐methods design was employed, incorporating quantitative pre‐ and post‐tests and qualitative semi‐structured interviews. The one‐way ANOVA results revealed that both AI groups significantly outperformed the CG across all measures, with no statistical difference between Bing and ChatGPT groups. The learners in AI‐supported conditions reported reduced hopelessness and improved IER and BERS, alongside notable vocabulary retention. In agreement with the quantitative results, the qualitative findings highlighted the engaging and supportive nature of AI environments, which led to improved IER, BERS and vocabulary retention and reduced hopelessness in the EFL learners. These results suggest that integrating AI tools like Bing and ChatGPT in EFL classrooms can enhance emotional well‐being and language acquisition, offering valuable pedagogical insights for educators seeking to leverage technology in language instruction.
Assessment of an activity that promotes community building, inclusion, and perseverance in introductory college biology courses
Authors: Bocetti Julie M. , Alvarez Valentina , Elmore Donald E. , Matthews Adam G. W. 
Published: February 2025

AbstractCommunity, inclusion, and perseverance are essential for student success in STEM. To promote these values, we developed two discussion‐based activities for implementation in introductory college STEM courses. Both activities incorporate watching videos that portray scientists telling the stories of their career trajectory, in‐class discussions, and individual reflection. The first activity addresses community building and inclusion in the classroom, while the second activity focuses on perseverance and student definitions of success. These activities were fully implemented into sections of introductory biology during the 2020–2021 academic year. We assessed how effectively these activities addressed their learning goals through analysis of student written responses and a survey given before and after activities. Overall, the activities were successful helping students achieve learning goals related to community, inclusion and perseverance.
Systematic Investigation of Metabolism and Potential Pharmacological Mechanism of Tanreqing Injection to Human Lower Respiratory Tract Infection Based on UPLC–Q–TOF–MSE and Network Pharmacology
Authors: Wang Huanlu , Mai Xi , Jing Yan , Liu Shuhao 
Published: February 2025

ABSTRACTTanreqing injection (TRQI), a well‐known traditional Chinese medicine, has a marked curative effect on lower respiratory tract infections. A strategy using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry (UPLC–Q–TOF–MSE) for rapid identification of metabolites from TRQI was proposed by UNIFI informatics platform combined with multiple data processing techniques. Target prediction was then performed based on the original compounds in vivo, and a network between the active compounds and common targets was established using Cytoscape v3.9.0. As a result, 64 original compounds were characterized in TRQI, and 54 original compounds and 76 metabolites of TRQI were detected in human plasma and urine, two of which (M28 and M45) were novel metabolites. A novel metabolic pathway for lonicerin was identified. The compound‐target‐pathway network identified 22 target genes and 20 signaling pathways that were linked to these mechanisms. The key mechanism is related to the JAK‐STAT signaling pathway and PI3K‐Akt signaling pathway. The bioactive ingredients and mechanisms of action of TQRI against lower respiratory tract infections based on original compounds in vivo were explored through network pharmacology and molecular docking. This is the first study in which the mechanism of action of TRQI in humans has been clarified.
Meta‐Analysis of the Safety and Efficacy of Intensive Blood Pressure Control After Thrombectomy
Authors: Bao Qiang Ji , Li Yi Ming , Wu Xinting , Li Yun Ting , Huang Xiao Long , Zhou Hui , Zhang Xiao Qiang , Wang Xue Jun 
Published: February 2025

ABSTRACTPurposeAfter successful endovascular treatment of acute ischemic stroke, there remains considerable controversy surrounding the efficacy of intensified blood pressure control therapy. Presently, numerous randomized controlled trials have yielded diverse findings. Thus, our objective is to consolidate all current randomized controlled trial data to evaluate whether intensified systolic blood pressure targets, in comparison to standard targets, offer superior safety and efficacy.MethodsBy searching the EMBASE, PubMed, and Cochrane Library databases, we identified randomized controlled trials comparing standard blood pressure control to intensified blood pressure control in patients with acute ischemic stroke undergoing endovascular thrombectomy (EVT). Efficacy outcomes included favorable clinical outcomes (defined as a modified Rankin Scale (mRS) score of 0–2 at 90 days), excellence clinical outcomes (defined as an mRS score of 0–1 at 90 days), and 90‐day mortality. Safety outcomes included symptomatic intracranial hemorrhage (sICH). The relationship between standard and intensified blood pressure control post‐EVT and the prognosis of patients with acute ischemic stroke undergoing endovascular thrombectomy was expressed using risk ratios (RR) and their corresponding 95% confidence intervals (95% CI).ResultsThe analysis encompassed four studies involving a total of 753 patients. After sensitivity analysis and exclusion of literature with significant heterogeneity, it was revealed that compared to intensified blood pressure control, standard blood pressure control was associated with excellent clinical outcomes RR of 0.81 (95% confidence interval [CI]: 0.73–0.90; p < 0.05; I2 = 25%). However, no significant correlation was found for favorable clinical outcomes, 90‐day mortality, and safety outcomes including symptomatic intracranial hemorrhage.ConclusionsAfter careful analysis, our conclusion is that intensified blood pressure control, compared to standard blood pressure control following endovascular treatment in acute stroke patients, does not yield better clinical outcomes and may even lead to inferior ones. Moreover, there is no significant disparity in terms of safety between the two approaches.
Exploring the Effects of Cerebellar tDCS on Brain Connectivity Using Resting‐State fMRI
Authors: Catoira Beatriz , Lombardo Debora , De Smet Stefanie , Guiomar Raquel , Van Schuerbeek Peter , Raeymaekers Hubert , Deroost Natacha , Van Overwalle Frank , Baeken Chris 
Published: February 2025

ABSTRACTPurposeThe cerebellum's role extends beyond motor control, impacting various cognitive functions. A growing body of evidence supports the idea that the cerebellum optimizes performance across cognitive domains, suggesting critical connectivity with the neocortex. This study investigates how cerebellar transcranial direct current stimulation (tDCS) targeting the right Crus II region modulates functional brain connectivity.MethodUsing a within‐subject design, 21 healthy participants underwent both sham and anodal cerebellar tDCS at 2 mA during 20 min of concurrent resting‐state fMRI sessions. Data was preprocessed, and connectivity changes were examined using seed‐to‐voxel analysis. Given the potential impact of cerebellar dysfunctions on symptoms associated with autism spectrum disorders, we also assessed how individual autism quotient (AQ) scores might influence cerebellar functional connectivity. Moreover, electrical field simulations were computed for each participant to explore the effects of individual differences.FindingsResults indicated increased functional connectivity between the cerebellar Crus II and the right inferior frontal gyrus (IFG) during active tDCS compared to sham stimulation. The IFG (part of the Action Observation Network) plays a crucial role in understanding the actions and intentions of others, implicating the cerebellum in higher‐order cognitive processes. In addition, linear mixed‐effects models revealed an interaction between electric field strength and AQ scores, suggesting that functional connectivity changes are based on individual psychobiological differences.ConclusionCerebellar tDCS significantly altered functional brain connectivity, particularly between the cerebellar Crus II and the IFG, both involved in social cognition. These findings contribute to our understanding of the cerebellum's role beyond motor control, highlighting its impact on cognitive and social processes and its potential for therapeutic applications, such as autism spectrum disorders.
Exploring the Relationship Between Serum Neuronal Pentraxin 2 and Poststroke Cognitive Impairment in Patients With First‐Episode Acute Ischemic Stroke
Authors: Li Jie , Ma Wenyang , Gu Shiyuan 
Published: February 2025

ABSTRACTBackground and Objective: Neuronal pentraxin 2 (NPTX2) is associated with cognitive impairment in some neurodegenerative diseases. However, few studies focused on the association between NPTX2 and poststroke cognitive impairment (PSCI). Hence, this study aimed to investigate the association between serum NPTX2 levels and PSCI.Methods: A total of 134 participants with acute ischemic stroke (AIS) and 42 normal controls were enrolled in this study. Admission baseline information was collected, and serum NPTX2 levels were determined within 24 h using enzyme‐linked immunosorbent assay (ELISA) at hospital admission. All subjects were evaluated for cognitive function using the MoCA (Montreal Cognitive Assessment) scale at 3 months after stroke onset, and patients with AIS were divided into PSCI and PSNCI (poststroke no cognitive impairment) groups, with a total MoCA score < 26 defined as PSCI. This study analyzed the relationship between serum NPTX2 and MoCA score and the risk factors of PSCI. The receiver operating characteristic (ROC) curve was to evaluate the diagnostic value of serum NPTX2 levels on PSCI.Results: Among the 134 AIS participants, 53 (38.8%) patients suffered from PSCI at 3 months after stroke onset. The serum levels of NPTX2 in the PSCI group, PSNCI group, and normal controls group were significantly different (p < 0.05). The serum NPTX2 levels in the PSCI and PSNCI groups were higher than normal control group, and the serum NPTX2 levels in the PSCI group were lower than PSNCI group (p < 0.05). Serum NPTX2 levels were positively correlated with the total score of MoCA (r = 0.329, p < 0.01), and also positively correlated with some subcognitive domains of MoCA (visuospatial and executive functions, naming, delayed memory, and attention). ROC curve indicated that serum NPTX2 predicted cognitive impairment in AIS patients. Multivariate Logistic regression analysis indicated serum NPTX2 was an independent protective factor for PSCI (odds ratio [OR] = 0.075, 95% CI 0.010–0.812, p < 0.01).Conclusions: Lower serum NPTX2 levels were associated with PSCI within 3 months in patients with first‐episode AIS. Lower levels of serum NPTX2 may be associated with impairment in visuospatial and executive functions, naming, delayed memory, and attention, while a further larger‐scale study is needed to verify our findings.
Cross‐Modal Transfer Effects of the Go/No‐Go Training With Visual Stimuli
Authors: Hori Maiko , Kojima Sho , Onishi Hideaki 
Published: February 2025

ABSTRACTIntroductionMotor task performance guided by one sensory modality (e.g., visual stimuli) can be improved by training; however, whether this training can also improve performance on the same task guided by another sensory modality remains uncertain (e.g., tactile stimuli). This study examined the effects of Go/No‐go task training using visual stimulus cues on Go/No‐go task performance using tactile cues and whether training also influences the dominance of the sensory modality.MethodsGo/No‐go tasks and a temporal order judgment (TOJ) task were performed by 24 right‐handed, healthy adults on days 1 and 5 of the 5‐day experiment. Furthermore, a subpopulation (the training group) practiced the Go/No‐go task with visual stimulus cues on days 2–4, whereas the remaining control group did not practice the task.ResultsThe training group demonstrated significantly reduced reaction times (RTs) on both the visual and tactile Go/No‐go tasks by day 5, whereas the control group demonstrated significantly reduced RTs only on the tactile Go/No‐go task. The RT change was also significantly greater in the training group than in the control group for both modalities. Conversely, no significant change in the TOJ for visual and tactile stimuli was observed between the groups.ConclusionThese results indicate that motor training with visual guidance can improve performance on the same task guided by tactile stimuli, possibly due to neuroplastic changes in the multimodal association cortices.
Somatosensory‐Thalamic Functional Dysconnectivity Associated With Poststroke Motor Function Rehabilitation: A Resting‐State fMRI Study
Authors: Zhang Haojie , Zhao Jun , Fan Lingzhong , Gao Chaohong , Li Fang , Liu Jingya , Bai Chen , Li Xingzhu , Li Bingjie , Zhang Tong 
Published: February 2025

ABSTRACTBackgroundThe thalamus plays a pivotal role in functional brain networks, yet its contribution to motor function recovery following stroke remains elusive. We aim to explore changes in thalamocortical functional connectivity poststroke and its correlation with motor function.MethodsThirty‐nine subacute ischemic stroke patients and 32 healthy individuals underwent resting‐state functional magnetic resonance imaging (MRI). The Fugl–Meyer Assessment (FMA) was employed to evaluate upper and lower extremity motor function before and 1 year after stroke rehabilitation. The ipsilesional thalamus and contralesional thalamus were parceled into functional regions of interest (ROIs) based on connectivity with six cortical ROIs: prefrontal, motor, temporal, posterior parietal, somatosensory, and occipital cortex. Functional connectivity between each cortical ROI and its corresponding thalamic ROI was calculated and compared between groups. Differences identified in the ROI‐to‐ROI analysis were further investigated through seed‐to‐voxel whole‐brain connectivity analyses to pinpoint thalamic dysconnectivity. Correlations with upper and lower extremity motor function were also analyzed.ResultsSignificant changes in thalamocortical functional connectivity were observed after stroke in ROI‐to‐ROI analysis, with bilateral somatosensory‐thalamic connectivity decreased and ipsilesional temporal‐thalamic and bilateral occipital‐thalamic connectivity increased. Seed‐to‐voxel analysis localized ipsilesional thalamic hypoconnectivity to the ipsilesional rolandic operculum and ipsilesional precentral gyrus. Ipsilesional somatosensory‐thalamic connectivity was positively correlated with baseline upper extremity FMA scores and negatively correlated with upper extremity motor function change rate at 1‐year postdischarge.ConclusionsThis study provides new insights into the role of the thalamus in motor function recovery after stroke, offering preliminary evidence for its potential as a therapeutic target in poststroke rehabilitation.