bluuebunny/crossref_metadata_2025_split huggingface dataset:
Local Detection of Ground Coupled Acoustic Waves with Seismic Arrays and Their Potential Role in the Discrimination of Explosions and Earthquakes
Authors: Adedeji Olumide , Schmandt Brandon 
Published: May 2024

Abstract
Acoustic waves are widely used to characterize explosive sources such as volcanoes, meteorites, and controlled explosions. This study examines the potential role of ground coupled airwaves (GCA), which effectively propagate at acoustic speeds (∼0.34 km/s) before coupling to the ground near seismometers, in aiding local discrimination between low-yield explosions in shallow boreholes and earthquakes. GCA generated by shallow borehole explosions from the 2014 imaging magma under St. Helens experiment (ML 0.9–2.3) and earthquakes (ML 2–3.4) from 2014 to 2016, were recorded by various seismometers at &lt;150 km source–receiver distance. Potential GCA are analyzed using arrays of broadband seismometers (number of seismometers, n = 85), nodal seismometers with 10-Hz geophones atop the surface (n = 904), and Texan dataloggers with shallowly buried 4.5-Hz geophones (n = 2535). Array-based detections are defined using the distributions of short-time average over long-time average functions in time windows during and adjacent to the predicted GCA arrival for direct source–receiver transmission. GCA are detected for 14 of 23 borehole explosions and 0 of 34 earthquakes. All detections occurred during times of low-mean wind speed (&lt;0.5 m/s) at ground-based weather stations. GCA amplitudes exhibit strong spatial variability, and the number of spatially distributed receivers appears more important for GCA detection than the type of seismometer installation. GCA detections were compared with seismic P/S amplitude ratios, which are a common source discriminant, and field logs of whether the borehole explosions ejected any mass or deformed the surface. No clear correlation was found with either type of source information, suggesting that heterogeneous propagation and near-receiver effects like wind noise are more influential than variations in source processes among the 23 explosions. Our results indicate that local seismic detection of GCA may valuably complement discrimination metrics like P/S ratios, with a low tendency for false-positive indications of explosions but a high tendency for false negatives.
Pengaruh Work From Home terhadap Job Satisfaction yang Dimediasi Work Life Balance dan Dampaknya terhadap Employee Performance Industri Perbankan di Jakarta
Authors: Wahyuni Siti , Tanuwijaya Justine , Gayatri Aisyah , Maulana Adam , Mirici Ismail Hakki 
Published: May 2024

This study aimed to analyze the effect of work from home on job satisfaction mediated by work life balance and its impact on employee performance in the banking industry in Jakarta with the variables work from home, job satisfaction, and organizational identification as independent variables and employee performance as the dependent variable, work life balance as a mediating variable. The method used in sampling in this study was purposive sampling with a total of 200 employees as respondents. Hypothesis testing using the AMOS analysis tool. The results of testing the hypothesis in this study show that work from home has a positive effect on work life balance, work from home has a positive effect on job satisfaction, work life balance has a positive effect on job satisfaction, there is a work from home effect on job satisfaction which mediated by work life balance, job satisfaction has a positive effect on organizational identification, and organizational identification has a positive effect on employee performance.
Keywords: Work From Home, Work Life Balance, Job Satisfaction and Organizational Identification, Employee Performance
Analisis Putusan Banding Pengadilan Pajak Sengketa Nilai Pabean: Studi Kasus di KPU BC Tipe A Tanjung Priok
Authors: Sholihin Ahmad , Nuryanah Siti 
Published: May 2024

This study aims to evaluate and mitigate the factors causing the low victory of KPU BC Type A Tanjung Priok in the customs value dispute at the Tax Court. This study is qualitative with triangulation method of content analysis and interview. Data is obtained from the tax court decision on the customs value dispute for the period 2018 to 2020. The study found that factors that cause the low winnings on customs value disputes are the low effectiveness of collecting transaction evidence at the time of objection and the limitations of testing the validity of the evidence submitted by the Appellant during the appeal hearing process. This study provide a practical implication that KPU BC Type A Tanjung Priok can conduct further action to mitigate the loss of the appeal hearing for the customs value dispute by for example optimizing data requests to the applicant during the objection process, coordinating with the Document Examiner Officer (Pejabat Fungsional Pemeriksa Dokumen - PFPD) to improve the objection decision, and evaluating tax court decisions.
Keywords: Tax Dispute, Tax Court, Tax Appeal, Customs
Automatically targeting the dorsolateral subthalamic nucleus for functional connectivity-guided rTMS therapy
Authors: Zhao Na , Qiao Yang , Yue Juan , Jing Ying , Ge Qiu , Zhang Meng , Zhang Jianguo , Zhen Yuan , Xiang Yu-Tao , Wang Jue , Zang Yu-Feng 
Published: May 2024

Aim: Many resting-state functional magnetic resonance imaging (rs-fMRI) studies have provided evidence that repetitive transcranial magnetic stimulation (rTMS) exerts treatment effects via functional connectivity (FC) from a superficial stimulation target to a deep effective region. The dorsolateral subthalamic nucleus (DL-STN) is an effective target in deep brain stimulation surgery for Parkinson’s disease (PD), but its targeting highly depends on well-trained neurosurgeons and is not easily used for FC-guided rTMS. We aimed to devise a method for automatically localizing the DL-STN, and further develop a one-stop plug-in of rs-fMRI FC analysis to assist future individualized FC-guided rTMS.
Methods: Based on structural and iron-sensitive MRI of 78 participants, two raters defined the DL-STN coordinates with very high reliability. The averaged coordinates in the standard Montreal Neurological Institute (MNI) space were: left DL-STN, x: -11.89 ± 0.82, y: -14.51 ± 1.00, and z: -6.40 ± 1.01 and the right DL-STN, x: 12.53 ± 0.77, y: -13.97 ± 0.86, and z: -6.57 ± 0.99. As the individual distances from the averaged coordinates were less than 3 mm (within one voxel for most rs-fMRI studies) for all 78 participants, we defined the average coordinates as AutoSTN. We then developed a one-stop plug-in named Connectivity and Coordinates Converting Assistant Toolbox (CC-CAT) and performed AutoSTN FC analysis.
Results: The AutoSTN seed showed significant FC with the motor cortices in all participants.
Conclusion: The AutoSTN-based rs-fMRI FC could guide future rTMS on PD. The one-stop plug-in CC-CAT can be used for any FC-guided rTMS treatment.
Heme oxygenase-1 is involved in the erastin-induced ferroptosis in acute myeloid leukemia cells
Authors: Zhao Jingyuan , Tian Siyu , Liu Jinnan , Liu Sichu , Ma Xiaolu , Yuan Hong 
Published: May 2024

Abstract

Emerging evidences have suggested that ferroptosis is one of the targeted mechanisms in tumor therapy. However, whether erastin can induce ferroptosis in acute myeloid leukemia (AML) and the potential mechanisms remains to be explored. CCK8 assay was first used to detect the toxicity of erastin to human promyelocytic leukemia cells (HL60), and the toxicological effect of erastin on HL60 cells performed a significant dose-dependent manner. Ferroptosis in HL60 was affirmed through the manifestation of mitochondrial ultrastructural damage, accumulation of reactive oxygen species (ROS) and malondialdehyde (MDA), depletion of glutathione (GSH) and glutathione peroxidase (GPX)4. Proteomics analysis identified heme oxygenase-1 (HO-1) as a key protein involved in the ferroptosis pathway. Further experiments showed that activation of HO-1 with Hemin worsened erastin-induced ferroptosis, while inhibition of HO-1 with Znpp partially alleviated it , without affecting protein levels of P62, LC3B, and nuclear receptor coactivator (NCOA)4. Thus, our study has indicated that erastin significantly induced ferroptosis in HL60 cells, which can be reversed by ferrostatin-1 (Fer-1). Overexpression of HO-1 deteriorates erastin-induced ferroptosis, which can be partially alleviated by inhibition of HO-1 independent on ferritinophagy. Ferroptosis, as a new cell death mechanism, may provide new clues and strategies for the treatment of AML.
A remote health intervention to reduce impairing post-concussional mild-to-moderate symptoms in adults (GAIN Lite): Study protocol for a parallel group randomised trial
Authors: Pedersen Sedsel Kristine Stage , Thastum Mille Møller , Odgaard Lene , Næss-Schmidt Erhard Trillingsgaard , Pedersen Carsten Bøcker , Nygaard Charlotte , Pallesen Hanne , Silverberg Noah D , Brunner Iris 
Published: May 2024

Abstract

Background: Mild traumatic brain injury, commonly known as concussion, has been estimated to be around 600 per 100.000 yearly in Denmark, and 30-50 million new cases worldwide. Although complete resolution normally occurs within a few weeks, up to a third develop persistent post-concussion symptoms (PPCS) beyond 3 months. However, evidence for effective treatment strategies is scarce. The objective of this study is to evaluate the efficacy of the novel intervention GAIN Lite added to enhanced usual care (EUC) for adults with mild-to-moderate PPCS compared to EUC only.
Methods: An open-label, parallel-group, two-arm randomized controlled superiority trial (RCT) with 1:1 allocation ratio. Participants will be randomly assigned to either: 1) EUC or; 2) GAIN Lite added to EUC. GAIN Lite is characterized as a complex intervention and has been developed, feasibility-tested, and process evaluated before effect evaluation in the RCT. Sixty-six participants will be recruited to each group. Potential participants will be identified through the hospital's Business Intelligence portal of the Central Denmark Region or referred by general practitioners within 2-4 months post-concussion. Primary outcomes are mean changes in PPCS and limitations in daily life from baseline to 24 weeks after baseline
Discussion: GAIN Lite is a low-intensity intervention for adults with mild-to-moderate PPCS. Offering a remote intervention may improve access to rehabilitation and prevent chronification for individuals with mild-to-moderate PPCS. Moreover, GAIN Lite will facilitate access to healthcare, especially for those with transportation barriers. Overall, GAIN Lite may provide an accessible, flexible, and convenient way to receive treatment based on sound theories and previous evidence of effective interventions for adults with mild-to-moderate PPCS.
Trial Registration: URL: ClinicalTrials.gov Identifier:NCT05233475. Registered on 10th of February 2022.
The influence of environmental factors related to Juvenile Dermatomyositis (JDM), its course and refractoriness to treatment.
Authors: Valoes Clarissa C.M. , Arabi Tamima M. , Braga Alfésio L.F. , Campos Lucia M.A. , Kozu Katia T. , Aikawa Nadia E. , Silva Clovis A. , Farhat Sylvia C.L. , Elias Adriana M. 
Published: May 2024

Abstract

Objective To evaluate the influence of environmental factors and prematurity relating to juvenile dermatomyositis (JDM), its course and refractoriness to treatment.Methods A case-control study with 35 patients followed up at a tertiary hospital and 124 healthy controls, all residents in metropolitan area of São Paulo city. Patients were classified according to monocyclic, polycyclic or chronic disease courses and refractoriness to treatment. The daily concentrations of pollutants (inhalable particulate matter-PM10, sulfur dioxide-SO2, nitrogen dioxide-NO2, ozone-O3 and carbon monoxide-CO) were provided by the Environmental Company of São Paulo. Data from the population were obtained through a questionnaire.Results Fifteen patients had monocyclic course, and 19 polycyclic/chronic courses. Eighteen patients were refractory to treatment. Maternal occupational exposure to inhalable agents (OR = 17.88; IC 95% 2.15-148.16, p = 0.01) and exposure to O3 in the fifth year of life (third tertile > 86.28µg/m3; OR = 6.53, IC95% 1.60-26.77, p = 0.01) were risk factors for JDM in the multivariate logistic regression model. The presence of a factory/quarry at a distance farther than 200 from daycare/school (OR = 0.22; IC 95% 0.06–0.77; p = 0.02) was a protective factor in the same analysis. Prematurity, exposure to air pollutants/cigarette smoke/sources of inhalable pollutants in the mother's places of residence and work during the gestational period were not associated with JDM. Prematurity, maternal exposure to occupational pollutants during pregnancy as well as patient’s exposure to ground-level pollutants up to the fifth year of life were not associated with disease course and treatment refractoriness.Conclusion Risk factors for JDM were maternal occupational exposure and exposure to O3 in the fifth year of life.
Biomonitoring of Yozgat Çamlık National Park’s Anthropogenic Microfiber Pollution: A Comprehensive Analysis of Lichen-Supported Air Quality Assessment and Microplastic Composition Insights
Authors: Kocakaya Zekiye , Yılmaz Erkan , Duman Fatih , Kocakaya Mustafa , Pekdemir Sami 
Published: May 2024

Abstract

The use of bioindicator organisms such as lichens has been a longstanding field of study to demonstrate levels of environmental pollution, as they are sensitive to air pollution but can also withstand and live in polluted environments, making them ideal for assessing air pollution levels. This study aimed to measure the level of anthropogenic microfibres, a type of microplastic, in lichen samples collected from Yozgat Çamlık National Park (Turkey). In the Yozgat Çamlık National Park region, 3 groups have been formed, starting from the region where the people are most crowded, towards the far regions where fewer people set foot. A comparative study was carried out in terms of the type and number of anthropogenic microfibres in lichen samples taken from these regions. In order to take anthropogenic microfibres from lichen samples into the analysis environment, a wet peroxide oxidation was used, followed by passing the fibres through special filters. Rose Bengal staining method was used to separate the synthetic material from the organic material. Stereo microscope was used to determine their size and color. Anthropogenic microfibres ranging from 0.15 to 4.2 mm in length were found. The study revealed that blue microfibres was the most one in three regions. To identify the plastic type, Fourier-transform infrared spectrometer (FT-IR) with microscope property and micro-Raman spectrometer were conducted, and the obtained results were compared with literature studied and FTIR library to determine the plastic types. Based on the results, the most commonly found microplastics in the study area were Polyurethane (42%), Acrylonitrile Butadiene Styrene (25%), and Polyethylene Terephthalate (13%), respectively. The obtained all results reinforces the potential applicability of lichens as a reliable tool for biomonitoring atmospheric microfibres deposition. Consequently, the findings highlight the significance of using lichens as bioindicators to evaluate the levels of air pollution in a particular region and determine the effectiveness of pollution mitigation efforts.
Treatment of Paravertebral Arteriovenous Fistula with detachable coils plus Onyx Embolization : Case Report
Authors: Li Can , Li Xi feng , Feng Xin , Liu Wen chao , Li Ran , Guo Shen quan 
Published: May 2024

Abstract

The patient, a 47-year-old female, presented with a four-year history of recurrent dizziness that worsened over the past four months and experienced an intracranial murmur in the last month. Magnetic resonance imaging and cerebral digital subtraction angiography confirmed the presence of paravertebral arteriovenous fistula. This patient exhibited smooth recovery following endovascular intervention involving detachable coils plus Onyx.
Lateral Motor Column specific expression of Sonic Hedgehog contributes to maintenance and scaling of pMN progenitor cell populations during oligodendrogenesis
Authors: Kottmann Andreas , Starikov Lev , Ghinia-Tegla Miruna 
Published: May 2024

Abstract

Motor neurons (MNs) and oligodendrocyte precursor cells (OPCs) emerge sequentially from the pMN precursor domain during spinal cord development. MNs diversify into muscle specific subtypes and settle in stereotypic locations in the ventral horns. In contrast, OPCs are mobile and appear to evenly populate the parenchyma. Whether earlier born MNs influence OPC production is controversial. We found that Sonic Hedgehog signaling emanating from nascent MNs of the lateral motor column is critical for maintaining a larger and more yielding pMN domain at limb levels compared to trunk levels during OPC production. Reduced Shh signaling resulted in unrecoverable diminishment of pMN domain based OPC production leaving the spinal cord impoverished of OPC. Our results suggest that production of OPC at limb levels is contingent on completion of MN production.
Association between frailty and chronic kidney disease: Findings from CHARLS
Authors: Yuan Jiamin , liu fang 
Published: May 2024

Abstract

Objectives: To investigate prevalence of frailty in CKD individuals and the relationship between frailty and CKD based on a large, nationally representative survey.
Design: Retrospective cohort study.
Participants: The participants were 4231 adults aged ≥50 years from the China Health and Retirement Longitudinal Study (CHARLS).
Measurements: Based on the FRAIL scale, frailty and prefrailty were defined. CKD was defined as eGFR less than 60 mL/min/1.73m2, calculated according to the CKD Epidemiology Collaboration (CKD-EPI) equation, or self-reported CKD. Logistic regression models were conducted to analyze the cross-sectional relationship between frailty and CKD. Cox proportional hazards regression models were used to examine the effect of frail status and frail components on CKD.
Results: We found that prevalence of frailty in CKD individuals was 13.9% while in patients without CKD was 8.4%. The prevalence of CKD in robust group was 6.0%, in prefrail group was 10.1% and in frail group was 14.0%. In frail status, after adjusted, the incidence of CKD was 1.713 (95% CI 1.109-2.646) in the frail group compared with robust group (P =0.015). While there was no statistical difference in the incidence of CKD among the prefrail group and robust group. In frail components, after adjusted, weight loss was associated with higher risk of CKD [HR (95% CI): 1.617 (1.170-2.235)].
Conclusion: The prevalence of frailty was relatively high in the population. In frail status, both prefrail and frail were associated with a higher risk of CKD. In frail components, weight loss was associated with an increase incidence of CKD. Frailty is reversible, so early identification of frailty may reduce the incidence of CKD and improve the adverse consequences associated with CKD.
Identifying the Medications with the Greatest Reduction in Mortality in Coronary Artery Dissection
Authors: Kazi Usman , Al-Nasseri Abraheim , Leavitt Nathaniel , Ho Huy , Cromwell Ryan , Reed Hunter , Zeidan Zeid , Pasupuleti Suman 
Published: May 2024

Abstract

Coronary artery dissection (CD) is a potentially fatal complication, usually arising either spontaneously or iatrogenically. Therefore, identifying treatment methods that reduce mortality is of great importance. The American College of Cardiology recommendations stipulate that patients who have experienced CD may benefit from beta-blocker therapy, as beta-blockers have been shown to reduce the incidence of recurrent CD. Currently, there is little published data in support of beta-blockers providing mortality reduction for CD. Given the significant risk of mortality from CD, we aimed to test the veracity of these recommendations using a retrospective multicenter study as well as having a main objective of exploring means to lower mortality in CD. We extracted data from 1190 patients with the diagnosis of CD. Our patients were identified and stratified based on common lab values and cardioprotective medications they were taking. Our data revealed that the odds ratio for mortality in patients with CD while on beta blockers was 0.375 (p-value 0.0009, confidence interval 0.210–0.669), and while on ACEi/ARBs was 0.447 (p-value 0.0077, confidence interval 0.247–0.808). These results indicate a significant reduction in mortality in patients who are taking beta-blockers and/or ACEi/ARB medications after being diagnosed with CD. Our data can be viewed as supportive of the current recommendation for the primary use of beta-blockers in patients with spontaneous CD, as well as suggesting angiotensin receptor blockers and angiotensin-converting enzyme inhibitors as possible additional therapies.
Patients’ perceptions of the efficacy, safety, and quality of the evidence of medicinal cannabis: a survey of Australian cancer patients.
Authors: Taylor Joseph , Fradgley Elizabeth , britton Ben , Martin Jennifer , Lucas Catherine , Carlson Melissa , Bridge Paula , Morris Sarah , Watts Gareth , Lynam James 
Published: May 2024

Abstract

Purpose: Despite the increased demand [8], and accessibility [5], to medical cannabis (MC) there is a general consensus among physicians that evidence on its efficacy [10,12,13], and safety [4,11], is lacking. Although research has explored medical professionals’ perceptions of MC [10, 12,13], to our knowledge there is minimal research exploring patients’ perceptions; particularly in an Australian cancer setting [14,15,16,17]. We therefore aimed to explore patients’ perceptions of the efficacy, safety, and evidence for MC.
Methods: A prospective cross-sectional questionnaire of Australian cancer patients attending adult oncology outpatient clinics in the Hunter New England Local Health District. Patients were 18 years, or older, and had a confirmed diagnosis of cancer (solid or haematological).
Results: 19% of our cohort were using MC. Despite using for symptom control such as pain (61%), and, in some cases perceived anti-cancer activity (12% to cure and 16% to slow the cancer); a minority of users believed that the evidence for either of these indications was of high quality (28% and 29% respectively). A minority of users (31%) were receiving information on MC from clinicians. Most instead rely on resources such as TV, friends, family, social media and websites.
Conclusion: This study demonstrated current real world cancer patients’ perceptions on: the evidence for MC, the sources of information used to shape their health beliefs, and compares users to non-users. The results highlight the need for treating teams to combat potential misinformation that patients may be accessing on MC and provide information on treatments with greater evidence.
Synthesis and Optical Properties of Co-Polycarbonate Containing Cardo Structure and Binaphthalene Structure
Authors: Li Chen , Wang Qingyin , Wang Gongying 
Published: May 2024

Abstract

In this paper, molten transesterification was used with diphenyl carbonate (DPC), 9,9'-bis[6-(2-hydroxyethoxy)naphthyl]fluorene (BNEF), 2,2'-bis(2-hydroxyethoxy)-1,1'-binaphthalene (BHEBN) were used as the polymeric monomers to prepare a series of co-polycarbonates with different molar feeding ratios. It is found that when the molar ratio of BHEBN and BNEF is 6:4, the copolymer has more comprehensive properties. The Mn of the copolymer is 23000 Mn, the Mw is 40700, and the PDI is 1.77. The glass transition temperature is 147.6℃, the initial thermal decomposition temperature (Td,5%) is 338.9℃, the refractive index is 1.6753, the Abbe number is 18.7, and the light transmittance is 86.23%.