bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factor Structure of the Mood and Anxiety Symptom Questionnaire does not Generalize to an Anxious/Depressed Sample
Authors: Boschen Mark J , Oei Tian P.S. 
Published: December 2009

Objective: The tripartite model of anxiety and depression has been proposed as a representation of the structure of anxiety and depression symptoms. The Mood and Anxiety Symptom Questionnaire (MASQ) has been put forwards as a valid measure of the tripartite model of anxiety and depression symptoms. This research set out to examine the factor structure of anxiety and depression symptoms in a clinical sample to assess the MASQ's validity for use in this population. Method: The present study uses confirmatory factor analytic methods to examine the psychometric properties of the MASQ in 470 outpatients with anxiety and mood disorder. Results: The results showed that none of the previously reported two-factor, three-factor or five-factor models adequately fit the data, irrespective of whether items or subscales were used as the unit of analysis. Conclusion: It was concluded that the factor structure of the MASQ in a mixed anxiety/ depression clinical sample does not support a structure consistent with the tripartite model. This suggests that researchers using the MASQ with anxious/depressed individuals should be mindful of the instrument's psychometric limitations.
Executive Functions in Obsessive–Compulsive Disorder: State or Trait Deficits?
Authors: Bannon Shelley , Gonsalvez Craig J. , Croft Rodney J. , Boyce Philip M. 
Published: December 2009

Objective: Despite the neuropsychology literature providing reliable evidence of impaired executive functions in obsessive–compulsive disorder (OCD), to date it has not been determined whether these deficits are trait-related (independent of symptomatology) or state-dependent (dependent on symptomatology). The current research examines the executive functions in OCD in a comprehensive manner and, for the first time, assesses the stability of these deficits over the developmental course of the disorder. Method: Using a cross-sectional design, Study 1 examined the executive functions (set shifting, inhibition, planning, verbal fluency and working memory) in 60 subjects (20 actively Symptomatic OCD, 20 Remitted OCD and 20 Panic Disorder). Using a longitudinal design, Study 2 reassessed a subsample of OCD subjects (participants in Study 1) once they reached remitted status. Results: Study 1 found that the OCD groups exhibited deficits in set shifting and inhibition relative to Panic Disorder controls; however, no deficits were observed in planning, verbal fluency or working memory. There were no differences found between the Symptomatic and Remitted OCD groups on any of the executive function measures. Study 2 found that the identified executive function deficits in individuals were stable over time and remained unchanged despite symptom remittance. Conclusion: Current results confirm the presence of specific executive function deficits in OCD, and indicate that these deficits are trait-like in nature.
Impact of a Crisis Assessment and Treatment Service on Admissions into an Acute Psychiatric Unit
Authors: Adesanya Adesina 
Published: December 2009

Objective: To assess the impact of a regional/rural crisis assessment and treatment service (CAT) on admissions into an acute adult inpatient psychiatric facility. Methods: Relevant data for admissions into an acute adult inpatient psychiatric facility in the 18 month periods before and after the establishment of a CAT were compared. Data extracted from available clinical records were transferred into an appropriately structured pro forma for statistical analysis. Results: There were 69 and 53 index inpatient unit admissions in the two time periods. The majority of these were for single, unemployed men aged in their 30s. Although statistically non-significant, the results appear to suggest that there were proportionately fewer readmissions and that admissions were likely to be influenced by illness severity and diagnostic considerations in the period following the establishment of the CAT. The establishment of CAT did not appear to have had much impact on the duration of psychiatric hospitalization. Conclusions: Crisis assessment and treatment services operating within a re-gional/rural integrated mental health setting appear to have only limited impact on hospitalization for psychiatric crisis presentations. There is a need for further studies looking at a broader range of outcome variables in the assessment of the impact of CAT on psychiatric hospitalization in such settings.
The Beyondblue Schools Research Initiative: Conceptual Framework and Intervention
Authors: Spence Susan , Burns Jane , Boucher Susan , Glover Sara , Graetz Brian , Kay Debra , Patton George , Sawyer Michael 
Published: December 2009

Objective: To describe the rationale, conceptual framework and content of the intervention for the beyondblue Schools Research Initiative. Conclusions: The beyondblue Schools Research Initiative aims to prevent the development of depression in young people through increasing individual and environmental protective factors within the school context. The model draws on evidence that demonstrates the important role played by individual and environmental characteristics in buffering the impact of adversity. The school provides a forum in which both individual and environmental change may be produced in order to increase some of these key protective characteristics. The project also draws together health, education and other key services to provide more effective pathways to enable young people to receive professional help when required.
Mental Health Research in General Practice
Authors: Minas Harry , Klimidis Steven , Kokanovic Renata 
Published: December 2009

Objective: To explore problems in carrying out a mental health research project in the general practice setting. Method: Open-ended interviews were conducted with general practice stakeholders, focusing on impediments to the conduct of mental health research in general practice and possible means for improving the participation of general practitioners in such research. Participants in the consultations were members of ?ve divisions of general practice, senior staff within an academic department of general practice, four general practitioners and a research group engaged with general practice research. The discussions were recorded in detailed interview notes, and key issues and themes emerging from consultations were derived by the researchers. Results: Three main themes summarized most of the issues reported through the consultations, including structural issues (e.g. disruption of practice, time limitations and lack of remuneration), process issues (e.g. researcher–general practice communication, researcher-imposed issues and need for partnerships) and content issues (e.g. study design, study procedures and methods). Conclusions: The consultations revealed similar ?ndings to previously published reports concerning general practice research, with an emphasis on the need for partnerships between researchers and general practice organizations in the conduct of such research.
A Model of Supervision in Mental Health for General Practitioners
Authors: Hodgins Gene , Judd Fiona , Kyrios Michael , Murray Greg , Cope Andrew , Sasse Christina 
Published: December 2009

Objective: If general practitioners (GPs) are to provide effective ongoing care to patients with mental health difficulties, it is argued that they need access to effective supervision. This paper aims to describe a specific framework for the provision of supervision to GPs involved in mental health-related work in a rural area. Conclusions: An innovative model of supervision is currently being trialled with GP practices in the Bendigo area of country Victoria. It is essential for a formal supervision framework to be available for GPs in mental health, so that effective outcomes in primary mental health care are maximized, facilitating better support for GPs and better outcomes for patients with mental health difficulties.
The New South Wales Inebriates Act: Going, Going, Gone?
Authors: Shea Peter 
Published: December 2009

Objective: To describe how the use of psychiatric hospitals as institutions for inebriates came about in New South Wales. Conclusions: A so-called ‘temporary’ solution to a political problem in 1929 led to the psychiatric hospitals in New South Wales becoming repositories for inebriates for the next 75 years. This unsatisfactory situation may be about to change.
Discovery of a novel type of body scale in the marine dinoflagellate, Amphidinium cupulatisquama sp. nov. (Dinophyceae)
Authors: Tamura Maiko , Takano Yoshihito , Horiguchi Takeo 
Published: December 2009

SUMMARYA new species of Amphidinium, A. cupulatisquama Tamura et Horiguchi, from sand samples from Ikei Island, Okinawa Prefecture in subtropical Japan, is described based on light, scanning and transmission electron microscopy and the partial sequencing of the large subunit rDNA gene. The species has a typical morphology for the genus, but is distinguished from previously described species by having a combination of the following characteristics: (i) a relatively large cell (over 30 µm in length); (ii) possessing an eyespot on the dorsal side of the cingulum; (iii) the longitudinal flagellum emerging from a point close to the cingulum; (iv) cell division taking place in the motile phase; and (v) possessing body scales. This is the third species of this genus to possess body scales. The body scales of A. cupulatisquama are uniform and cup‐shaped in side view and elliptical in face view. Their dimensions are 136.4 nm by 91.0 nm by 81.8 nm high. In side view, the scale is seen to have a thick lower half and a thin upper half. This scale type is very different from those of previously reported Amphidinium species (HG114 and HG115). The molecular tree indicated that A. cupulatisquama and the two other strains of body scale‐bearing Amphidinium are distantly related within the Amphidinium clade.
ENDOPHTHALMITIS FOLLOWING CATARACT EXTRACTION
Authors: McCLELLAN K. , COSTER D. J. , BADENOCH P. R. , SANDERS R. , CHANDRARATNAM E. , KUPA A. 
Published: December 2009

AbstractWe describe a case of bacterial endophthalmitis complicating routine cataract extraction and intraocular lens implantation in a 97‐year‐old woman. The ocular and systemic factors that may have predisposed to intraocular infection in this case, and the possibility of predicting these pre‐operatively, are discussed.
Sex differences in language first appear in gesture
Authors: Özçalışkan Şeyda , Goldin‐Meadow Susan 
Published: December 2009

AbstractChildren differ in how quickly they reach linguistic milestones. Boys typically produce their first multi‐word sentences later than girls do. We ask here whether there are sex differences in children’s gestures that precede, and presage, these sex differences in speech. To explore this question, we observed 22 girls and 18 boys every 4 months as they progressed from one‐word speech to multi‐word speech. We found that boys not only produced speech + speech (S+S) combinations (‘drink juice’) 3 months later than girls, but they also produced gesture + speech (G+S) combinations expressing the same types of semantic relations (‘eat’ + point at cookie) 3 months later than girls. Because G+S combinations are produced earlier than S+S combinations, children’s gestures provide the first sign that boys are likely to lag behind girls in the onset of sentence constructions.
Learning design and assessment with e‐tivities
Authors: Armellini Alejandro , Aiyegbayo Olaojo 
Published: December 2009

AbstractThis paper reported on the findings of research into innovation in e‐learning design and assessment through the development and implementation of online learning activities (e‐tivities). The focus of the study was on Carpe Diem as a process to enable academic course teams to seize 2 days to design and embed pedagogically appropriate e‐tivities into their courses. The study also addressed the use of technology in the design of e‐tivities and the level of tutor and learner engagement with them during course delivery. Six academic course teams representing three disciplines at four British universities took part in this 12‐month study. Cognitive mapping was the main research methodology used. The results suggested that Carpe Diem is an effective and powerful team‐based process to foster pedagogical change and innovation in learning design and assessment practices. The e‐tivities designed during Carpe Diem were successfully used primarily for learning and formative assessment, and exceptionally for summative assessment. Web 2.0 tools, especially wikis, were employed to enable collaborative online learning and were prominent in the new designs. The tutors' e‐moderation skills were key to engage learners and thus capitalise on the benefits of e‐tivities.
AMACR is not applicable as a diagnostic tool in hepatocellular carcinoma
Authors: WILLEMOE GRO LINNO , VAINER BEN 
Published: December 2009

Willemoe GL, Vainer B. AMACR is not applicable as a diagnostic tool in hepatocellular carcinoma. APMIS 2010; 118: 85–90.α‐methylacyl coenzyme A racemase (AMACR or P504S) is a mitochondrial and peroxisomal protein present in a variety of human cells. Demonstration of increased expression is used diagnostically in prostatic adenocarcinoma. AMACR is also produced by normal hepatocytes and it has been postulated that the demonstration of AMACR expression or its pattern of distribution is useful in the diagnosis of hepatocellular carcinoma (HCC) (Jiang et al., Hum Pathol 2003;34, Guzman et al., Appl Immunohistochem Mol Morphol 2006;14, Li et al., J Exp Clin Cancer Res 2008;27). The aim of the present study was to evaluate whether immunohistochemical staining for AMACR can be used in a routine histopathologic setting. Immunohistochemical staining for AMACR was performed on paraffin‐embedded tissue from livers resected for HCC during 1980–2006 at Rigshospitalet, Copenhagen, Denmark (n = 44). Tumor sections as well as surrounding non‐neoplastic tissues were studied. In both tumor and non‐tumor tissues, intracellular localization and staining pattern were assessed and the staining intensity of AMACR was graded. The fraction of stained tumor cells was not significantly different from that of stained non‐tumor cells in the same patients (p = 0.97). A significantly lower staining intensity was observed in clear cell areas (p = 0.005), but the AMACR expression did not correlate with the HCC type and could not distinguish neoplastic from non‐neoplastic liver cells. AMACR is not applicable as a tool in the histopathologic diagnosis of HCC.
EFFECT OF CRYOPROTECTANT MIXTURES ON RHEOLOGICAL PROPERTIES OF FRESH AND FROZEN/THAWED MASHED POTATOES
Authors: ALVAREZ MARÍA DOLORES , FERNÁNDEZ CRISTINA , CANET WENCESLAO 
Published: December 2009

ABSTRACT Hydrocolloids and protein were added to fresh (F) and frozen/thawed (F/T) mashed potatoes in the form of mixtures of: (1) amidated low‐methoxyl (ALM) pectin and xanthan gum (XG); (2) kappa‐carrageenan (k‐C) and XG; and (3) sodium caseinate (SC) and XG. F and F/T mashed potatoes without added biopolymers and with XG at 1.5 g/kg were also analyzed. Flow curves fit the power law and Casson models well – and preferentially the first of these. The Cox–Merz rule was not applicable to the steady and dynamic shear data on all of the mashed potatoes. In the F products, the departure of mashed potatoes–biopolymer mixtures from the Cox–Merz rule was XG concentration‐dependent. It was concluded that most of the F mashed potatoes followed the linear modified Cox–Merz rule, with η*(ω) and ηa() well superimposed. However, after processing, the linearity – or otherwise of the relationship between viscosities – was more dependent on the type of biopolymer mixture. Also, in the case of the F/T mashed potatoes without added biopolymers and with added ALM/XG binary mixtures, the relationships may be considered linear. Conversely, in the case of F/T mashed potatoes with added XG alone and mixed with k‐C and SC, small amplitude dynamic properties cannot be used directly to predict changes in texture perceived in the mouth given that the relationship between these properties and steady shear measurements is nonlinear. The effects of addition of either XG alone or binary mixtures to F and F/T mashed potatoes were very dependent on the magnitude of the strain deformation applied to the system (i.e., low strain in oscillatory shear and high strain in steady shear).PRACTICAL APPLICATIONSMashed potato can be a suitable food for freezing as a ready‐meal component or as a single product in the form of potato gratin. Freezing and thawing processes reduce most of the quality parameters measured in the product. One way of minimizing damage from freezing and thawing is to incorporate cryoprotectants to alter crystal shapes. Previous studies have shown that xanthan gum (XG) is preferred for sensory purposes because of its creamy mouthfeel. The result of this study could serve as a guide for thickening of mashed potatoes by addition of a kappa‐carrageenan (k‐C)/XG blend, and also for softening of the product by addition of a sodium caseinate (SC)/XG mix together. These data have served as a resource in order to further explore the utilization of XG mixed with either k‐C or SC in developing commercially prepared frozen/thawed mashed potatoes.
Hypericin Hydroquinone: Potential as a Red‐Far Red Photosensitizer?
Authors: Theodossiou Theodossis A. , Tsiourvas Dimitris , Hothersall John S. 
Published: December 2009

AbstractHypericin hydroquinone is the product of two‐electron reduction of hypericin (quinone), a potent phenanthroperylenequinone photosensitizer. In contrast to the quinone, the hydroquinone exhibits strong absorbance in the far‐red spectral region. Herein we provide initial evidence on the potential of hypericin hydroquinone as a far‐red photosensitizer.
Updated Functional Classification of β-Lactamases
Authors: Bush Karen , Jacoby George A. 
Published: December 2009

ABSTRACT
Two classification schemes for β-lactamases are currently in use. The molecular classification is based on the amino acid sequence and divides β-lactamases into class A, C, and D enzymes which utilize serine for β-lactam hydrolysis and class B metalloenzymes which require divalent zinc ions for substrate hydrolysis. The functional classification scheme updated herein is based on the 1995 proposal by Bush et al. (K. Bush, G. A. Jacoby, and A. A. Medeiros, Antimicrob. Agents Chemother. 39:1211-1233, 1995). It takes into account substrate and inhibitor profiles in an attempt to group the enzymes in ways that can be correlated with their phenotype in clinical isolates. Major groupings generally correlate with the more broadly based molecular classification. The updated system includes group 1 (class C) cephalosporinases; group 2 (classes A and D) broad-spectrum, inhibitor-resistant, and extended-spectrum β-lactamases and serine carbapenemases; and group 3 metallo-β-lactamases. Several new subgroups of each of the major groups are described, based on specific attributes of individual enzymes. A list of attributes is also suggested for the description of a new β-lactamase, including the requisite microbiological properties, substrate and inhibitor profiles, and molecular sequence data that provide an adequate characterization for a new β-lactam-hydrolyzing enzyme.
A semantic-based framework for multimedia management and interoperability
Authors: Tsinaraki Chrisa , Christodoulakis Stavros 
Published: December 2009

Interoperable, semantic-based audiovisual content services are necessary in the open Internet environment, where the volume of the available audiovisual information is growing rapidly. Such services can be built on top of structured, semantic-based audiovisual content descriptions. This thesis focuses on the representation and management of the audiovisual content semantics. The representation and management of the audiovisual content semantics are based on the dominant standards for audiovisual content description and ontology representation which are, respectively, the MPEG-7 and the OWL. In particular, the following components have been developed for the representation and management of the audiovisual content semantics:
• An MPEG-7 based model that allows: (a) The representation of the audiovisual content semantics; and (b) The representation of domain ontologies that extend the generalpurpose MPEG-7 semantics with domain knowledge and may be utilized in the audiovisual content description.
• An ontological infrastructure, which allows the representation and management of the audiovisual content semantics. This ontological infrastructure represents the MPEG-7 semantics and allows their extension with application-specific and domain-specific knowledge.
• A mapping model that allows interoperability support between MPEG-7 and OWL. This model maps the MPEG-7 constructs to OWL constructs and allows the transformation of OWL domain ontologies and OWL/RDF audiovisual content descriptions into MPEG-7 descriptions.
Numerical Investigation of Spectral Evolution of Wind Waves. Part I: Wind-Input Source Function
Authors: Tsagareli K. N. , Babanin A. V. , Walker D. J. , Young I. R. 
Published: December 2009

Abstract
This paper is dedicated to the investigation and calibration of the parameterized form for the wind-input source term Sin proposed earlier on the basis of field observations at Lake George, Australia. The main objective of this study was to obtain spectral forms for the wind-input source function Sin, which incorporates the novel observation-based features and at the same time satisfies the important physical constraint that the total integrated wind input must agree with independently observed magnitudes of the wind stress. Within this approach, a new methodology, a dynamic self-adjusting routine, was developed for correction of the wind-input source function Sin. This correction involves a frequency-dependent adjustment to the growth rate γ( f ), based on extrapolations from field data. The model results also show that light winds require higher-rate adjustments of the wind input than strong winds.
Triclinic titanite from the Heftetjern granitic pegmatite, Tørdal, southern Norway
Authors: Lussier A. J. , Cooper M. A. , Hawthorne F. C. , Kristiansen R. 
Published: December 2009

AbstractTwo crystals from a sample of titanite from the Heftetjern granitic pegmatite, Tørdal, southern Norway, were extracted for structure analysis and shown to have triclinic symmetry. Unit-cell parameters are as follows:a= 7.0696(4) Å,b= 8.7167(5) Å,c= 6.5695(3) Å, α = 89.7372(11)°, β = 113.7607(10)°, γ = 90.2929(13)°,V= 370.52(6) Å3for one crystal anda= 7.0612(5) Å,b= 8.7102(6) Å,c= 6.5628(4) Å, α = 89.7804(16)°, β = 113.7713(13)°, γ = 90.2502(16)°,V= 369.39(7) Å3for the other. The interaxial angles α and γ deviate from the value of 90° required for monoclinic symmetry by ~200–250 standard deviations. The single-crystal X-ray intensities were averaged in both monoclinic and triclinic Laue symmetries, givingR(merge) values of ~14% and ~1.3% respectively. For both crystals, more than 50 reflections withI> 3σIviolated the criterion for the presence of thea-glide required for monoclinicA2/asymmetry. Both crystals were refined in the space groupAwithZ= 4, and finalR1indices are 4.4% and 4.7% (wR2= 8.4 and 8.9%) respectively. The composition of one crystal was determined by electron microprobe analysis: Ca[Ti0.623Ta0.105Nb0.018Al0.137Fe0.0463+Sn0.0834+]Σ=1.012(SiO4)O. The characteristic corner-sharing [MO5] chains of identical octahedra observed in monoclinic titanite become chains of alternating M(1) and M(2) octahedra of different size, with the stronger X-ray scattering constituents concentrated at the M(2) site. Short-range bond-valence considerations suggest that theMcations will order as Al—O—Ta in adjacent octahedra, and when present in sufficient amounts, will couple along the chain to break long-range monoclinic symmetry.