bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short‐term recovery after subtotal and total abdominal hysterectomy—a randomised clinical trial
Authors: Persson P , Brynhildsen J , Kjølhede P ,   on behalf of the Hysterectomy Multicentre Study Group in South‐East Sweden
Published: January 2010

Please cite this paper as: Persson P, Brynhildsen J, Kjølhede P on behalf of the Hysterectomy Multicentre Study Group in South‐East Sweden. Short‐term recovery after subtotal and total abdominal hysterectomy—a randomised clinical trial. BJOG 2010;117:469–478.Objective  To determine whether the day‐by‐day postoperative recovery differs between women undergoing subtotal and total abdominal hysterectomy, and to analyse factors associated with postoperative recovery and sick leave.Design  A prospective, open, randomised multicentre trial.Setting  Seven hospitals and one private clinic in the south‐east of Sweden.Population  Two‐hundred women scheduled for hysterectomy for benign conditions were enrolled in the study, and 178 women completed the study. Ninety‐four women were randomised to subtotal abdominal hysterectomy; 84 women were randomised to total abdominal hysterectomy.Methods  The day‐by‐day recovery of general wellbeing was measured on a visual analogue scale in a diary 7 days preoperatively and 35 days postoperatively. Psychometric measurements included depression, anxiety and general psychological wellbeing.Main outcome measures  Effects of operating method and preoperative wellbeing on the day‐by‐day recovery and duration of sick leave.Results  No significant difference was found in the day‐by‐day recovery between operating methods. The day‐by‐day recovery of general wellbeing and duration of sick leave was strongly associated with the occurrence of minor complications, but not with major complications. The level of psychological wellbeing preoperatively was strongly associated with the day‐by‐day recovery of general wellbeing and duration of sick leave.Conclusions  Day‐by‐day recovery of general wellbeing is no faster in subtotal versus total abdominal hysterectomy. Independent of operation method there is an interaction between preoperative psychological wellbeing, postoperative recovery of general wellbeing and the duration of sick leave. Postoperative complications and preoperative psychological wellbeing are strong determinants for the duration of sick leave. There is a need for intervention studies with a focus on complications and preoperative wellbeing.
Are sexual problems more common in women who have had a tubal ligation? A population‐based study of Australian women
Authors: Smith A , Lyons A , Ferris J , Richters J , Pitts M , Shelley J 
Published: January 2010

Please cite this paper as: Smith A, Lyons A, Ferris J, Richters J, Pitts M, Shelley J. Are sexual problems more common in women who have had a tubal ligation? A population‐based study of Australian women. BJOG 2010;117:463–468.Objective  To investigate whether women who have had a tubal ligation are more likely to experience sexual problems than other women.Design  Population‐based telephone survey.Setting  Australia‐wide, including cities, regional towns, and rural areas.Population  A total of 3448 Australian women aged between 16 and 64 years.Methods  Women were surveyed using random‐digit dialling throughout 2004 and 2005.Main outcome measures  Prevalence of sexual problems and ratings of sexual satisfaction, relationship satisfaction, and sexual pleasure.Results  From a weighted sample of 2721 women, 447 (16.4%) reported having had a tubal ligation, with 85.0% currently aged between 40 and 64 years. Having a tubal ligation was not associated with any specific sexual problem, such as physical pain during sex or an inability to reach orgasm. In fact, after controlling for age and other sociodemographic differences, sterilised women were significantly less likely than non‐sterilised women to lack an interest in having sex (OR 0.69, 95% CI 0.54–0.89), to take ‘too long’ to reach orgasm (OR 0.69, 95% CI 0.50–0.96), to experience vaginal dryness during sex (OR 0.70, 95% CI 0.50–0.96), and to find sex unpleasurable (OR 0.64, 95% CI 0.46–0.90). Sterilised women were also more likely to experience extremely high levels of sexual satisfaction (OR 1.66, 95% CI 1.27–2.18), relationship satisfaction (OR 1.29, 95% CI 1.01–1.67), and sexual pleasure (OR 1.59, 95% CI 1.20–2.12).Conclusions  Our findings suggest no adverse effects, and possibly some benefits, for the sexual lives of women undergoing tubal ligation. These findings should be included with other educational material for couples considering sterilisation as a contraception option.
Evidence of placental haemorrhage and preterm delivery
Authors: Gargano JW , Holzman CB , Senagore PK , Reuss ML , Pathak DR , Williams MA , Fisher R 
Published: January 2010

Please cite this paper as: Gargano J, Holzman C, Senagore P, Reuss M, Pathak D, Williams M, Fisher R. Evidence of placental haemorrhage and preterm delivery. BJOG 2010;117:445–455.Objective  To evaluate evidence of placental haemorrhage (PH) obtained through maternal interviews, patient charts and placental pathology examinations as potential indicators of a ‘bleeding pathway’ to preterm delivery (PTD).Design  Prospective cohort.Setting  Fifty‐two clinics in five communities in Michigan, USA (1998–2004).Population  A subset (n = 996) of cohort participants with complete placental pathology data.Methods  First‐trimester bleeding and placental abruption were ascertained by mid‐trimester interviews and chart review, respectively. Disc‐impacting blood clot was defined as a gross placental examination finding of a blood clot impacting adjacent tissue. Microscopic haemorrhage was defined as ‘high’ (top quintile) scores on an aggregate measure of placental pathology findings suggestive of atypical maternal vessel haemorrhage. These four PH indicators were compared with one another and with risk of PTD assessed by logistic regression analyses.Main outcome measures  Preterm delivery and PTD subtypes (i.e. <35 weeks, 35–36 weeks; spontaneous, medically indicated) compared with term deliveries.Results  Placental abruption cases had 2.3‐fold to 5.5‐fold increased odds of the other three PH indicators. Disc‐impacting blood clots and microscopic haemorrhage were associated with one another (odds ratio [OR] = 4.6), but not with first‐trimester bleeding. In a multivariable model that included all four PH indicators and confounders, risk of PTD < 35 weeks was elevated with first‐trimester bleeding (OR = 1.9 [1.0, 3.4]), placental abruption (OR = 5.2 [1.7, 16.2]), disc‐impacting blood clots (OR = 2.3 [1.0, 5.0]) and microscopic haemorrhage (OR = 2.4 [1.4, 4.2]).Conclusions  Multiple clinical and subclinical PH indicators are associated with PTD, particularly early PTD.
The interrelationship of complement‐activation fragments and angiogenesis‐related factors in early pregnancy and their association with pre‐eclampsia
Authors: Lynch AM , Murphy JR , Gibbs RS , Levine RJ , Giclas PC , Salmon JE , Holers VM 
Published: January 2010

Please cite this paper as: Lynch A, Murphy J, Gibbs R, Levine R, Giclas P, Salmon J, Holers V. The interrelationship of complement‐activation fragments and angiogenesis‐related factors in early pregnancy and their association with pre‐eclampsia. BJOG 2010; 117:456–462.Objective  To determine the interrelationships during early pregnancy of complement‐activation fragments Bb, C3a and sC5b‐9, and angiogenesis‐related factors placental growth factor (PiGF), soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and soluble endoglin (sEng), and their associations with pre‐eclampsia.Design  Prospective cohort study.Setting  Denver complement study (June 2005–June 2008).Population  A total of 668 pregnant women with singleton gestations, recruited between 10 and 15 weeks of gestation.Methods  Using univariable and multivariable logistic regression analysis, concentrations of complement‐activation fragments and angiogenesis‐related factors were compared between 10 and 15 weeks of gestation in women who subsequently did or did not develop pre‐eclampsia. Interrelationships between these variables were tested using the non‐parametric Spearman rank correlation coefficient.Main outcome measure  Pre‐eclampsia. The association of complement‐activation fragments and angiogenesis‐related factors with obesity was also examined.Results  The mean (±SD) levels of complement Bb in early pregnancy among women who did and did not develop pre‐eclampsia were 0.84 (±0.26) μg/ml and 0.69 (±0.2) μg/ml, respectively (P = 0.001). Concentrations of PiGF were significantly (P = 0.01) lower (31 ± 12 pg/ml) in early pregnancy in the pre‐eclamptic group of women, as compared with the normotensive group (39 ± 32 pg/ml). The adjusted odds ratio (AOR) of Bb and PiGF were 2.1 (CI = 1.4–3.1, P < 0.0003) and 0.2 (CI = 0.07–0.7, P = 0.01), respectively. There was no significant difference in the levels of C3a, sC5b‐9, sFlt‐1 and sEng in early pregnancy among women who developed pre‐eclampsia, compared with women who remained normotensive during pregnancy. Higher levels of Bb (P = 0.0001) and C3a (P = 0.03), and lower levels of sFlt‐1 (P = 0.0002) and sEng (P = 0.0001) were found among women with obesity, compared with non‐obese controls. No meaningful relationships were found between the complement‐activation fragments and the angiogenesis‐related factors.Conclusions  In this cohort during early pregnancy, increased concentrations of complement‐activation factor Bb and lower concentrations of PiGF were associated with the development of pre‐eclampsia later in pregnancy.
CEO Pay‐For‐Performance Heterogeneity Using Quantile Regression
Authors: Hallock Kevin F. , Madalozzo Regina , Reck Clayton G. 
Published: January 2010

AbstractWe provide some examples of how quantile regression can be used to investigate heterogeneity in pay‐firm size and pay‐performance relationships for U.S. CEOs. For example, do conditionally (predicted) high‐wage managers have a stronger relationship between pay and performance than conditionally low‐wage managers? Our results using data over a decade show, for some standard specifications, there is considerable heterogeneity in the returns‐to‐firm performance across the conditional distribution of wages. Quantile regression adds substantially to our understanding of the pay‐performance relationship. This heterogeneity is masked when using more standard empirical techniques.
Signaling, Free Cash Flow and “Nonmonotonic” Dividends
Authors: Fuller Kathleen , Blau Benjamin M. 
Published: January 2010

AbstractMany argue that dividends signal future earnings or dispose of excess cash. Empirical support is inconclusive, potentially because no model combines both rationales. This paper does. Higher quality firms pay dividends to eliminate the free cash‐flow problem, while firms that outsiders perceive as lower quality pay dividends to signal future earnings and reduce the free cash‐flow problem. In equilibrium, dividends are nonmonotonic with respect to the signal observed by outsiders; the highest quality firms pay smaller dividends than lower perceived quality firms. The model reconciles the existing literature and generates new empirical predictions that are tested and supported.
Dividends versus Share Repurchases Evidence from Canada: 1985–2003
Authors: Kooli Maher , L'Her Jean‐François 
Published: January 2010

AbstractThis paper provides out‐of‐sample evidence on the payout policy in Canada during the 1985–2003 period. First, we show that the proportion of nonfinancial firms paying dividends has decreased, while the proportion initiating repurchase programs has increased. We also show that Canadian firms paying dividends and repurchasing shares are extremely concentrated. Second, we focus on the factors that could affect the choice between repurchases and dividends. We find that dividends and repurchases are used by different types of firms. While we do not confirm the financial flexibility hypothesis, our results are consistent with the substitution hypothesis after controlling for selection bias and endogeneity.
The Ex‐dividend Day: Action On and Off the Danish Exchange
Authors: Akhmedov Umid , Jakob Keith 
Published: January 2010

AbstractWe examine ex‐dividend day behavior on the Copenhagen Stock Exchange. We report price‐drop ratios of 32% and 18% for close‐to‐close and close‐to‐open samples, respectively, well below the ratios observed in the United States. Our findings are generally consistent with limit order adjustment explanations from recent literature. In Denmark, a unique average price trading opportunity makes it possible for investors to capture dividends without directly altering supply or demand in the regular market, and therefore not necessarily driving the price‐drop ratios toward one.
Debt Issuance in the Face of Tax Loss Carryforwards
Authors: Anderson Anne‐Marie , Nayar Nandu 
Published: January 2010

AbstractWe examine the market impact of issuances of public and private debt by firms with sizeable tax loss carryforwards (TLCFs). Public issuances are met with a significantly negative stock price reaction, while private placements are associated with a positive marginally significant stock price reaction. After controlling for asymmetric information proxies, the stock price reaction to the debt issuance is more negative, the larger the TLCF. The evidence suggests that debt financing is suboptimal when issuers have large TLCFs, which in turn, supports the relevance of taxes for debt usage.
Investors' Use of Historical Forecast Bias to Adjust Current Expectations
Authors: Kwag Seung‐Woog (Austin) , Shrieves Ronald E. 
Published: January 2010

AbstractWe explore the extent to which investor response to earnings information differs in the presence of historical bias in earnings forecasts. Overall, the results are consistent with the notion that investors take historical forecast bias into account when interpreting information in earnings announcements and that the market's reaction to forecast errors is larger (less negative) when forecasts are historically more optimistic and suggests that the functional form commonly used in the earnings response literature does not appropriately capture the effect of real unexpected earnings information (i.e., investors' expectation errors as opposed to analysts' forecast errors) on stock returns.
Changes in the Information Efficiency of Stock Prices: Additional Evidence
Authors: DeFusco Richard A. , Mishra Suchi , Raghunandan K. 
Published: January 2010

AbstractPrevious research shows, using data from three quarters after the implementation of regulation fair disclosure (Reg FD), that there is an improvement in the informational efficiency of stock prices after Reg FD. We compare the informational efficiency of stock prices in four pre‐Reg FD quarters (1999–2000) and 12 post‐Reg FD quarters (2002–2005). The improvement in the informational efficiency of stock prices previously reported in the immediate aftermath of Reg FD persists in later periods.
A Note on Affordability and the Optimal Share Price
Authors: Chittenden William T. , Payne Janet D. , Toles J. Holland 
Published: January 2010

AbstractDespite the increase in institutional ownership, decreased trading costs, and increased real personal savings, we find that the average stock price is lower today than it was in the 1920s. In the aggregate, the propensity to split is a function of recent market performance, personal savings, and the desirability of appearing to be a small firm. Our results indicate that, after decades of inflation and the average stock price falling, splitting stocks to return to an “affordable” trading range must be rejected as an explanation. This suggests that other economic forces are behind splits, whether traditional or behavioral in nature.
Modulation of platelet activation and initial cytokine release by alloplastic bone substitute materials
Authors: Klein M. O. , Kämmerer Peer W. , Scholz Thomas , Moergel Maximilian , Kirchmaier Carl Maximilian , Al‐Nawas Bilal 
Published: January 2010

AbstractObjectives: Platelet‐derived cytokines play a crucial role in tissue regeneration. In regenerative dental medicine, bone substitute materials (BSM) are widely used. However, initial interactions of BSM and platelets are still unknown. The aim of this study was to evaluate the potential of platelet activation and subsequent initial cytokine release by different commercial alloplastic BSM.Material and methods: Eight commercial BSM of different origins and chemical compositions (tricalcium phosphate, hydroxyapatite, bioactive glass: SiO2 and mixtures) were incubated with a platelet concentrate (platelet‐rich plasma, PRP) of three healthy volunteers at room temperature for 15 min. Platelet count, aggregation, degranulation (activated surface receptor CD62p) and cytokine release (Platelet‐derived growth factor, Vascular endothelial growth factor) into the supernatant were quantified. Highly thrombogenic collagen served as a reference.Results: The investigated PRP samples revealed different activation patterns when incubated with different BSM. In general, SiO2‐containing BSM resulted in high platelet activation and cytokine release. In detail, pure bioactive glass promoted platelet activation most significantly, followed by hybrid BSM containing lower ratios of SiO2. Additionally, we found indications of cytokine retention by BSM of large specific surfaces.Conclusions: Platelet activation as well as consecutive storage and slow release of platelet‐derived cytokines are desirable attributes of modern BSM. Within the limits of the study, SiO2‐containing BSM were identified as promising biomaterials. Further investigations on cytokine adsorption and cytokine release kinetics by the respective BSM have to be conducted. To cite this article:
Klein MO, Kämmerer PW, Scholz T, Moergel M, Kirchmaier CM, Al‐Nawas B. Modulation of platelet activation and initial cytokine release by alloplastic bone substitute materials. Clin. Oral Impl. Res. 21, 2010; 336–345 doi: 10.1111/j.1600‐0501.2009.01830.x
Osseointegration of one‐piece zirconia implants compared with a titanium implant of identical design: a histomorphometric study in the dog
Authors: Koch F. P. , Weng D. , Krämer S. , Biesterfeld S. , Jahn‐Eimermacher A. , Wagner W. 
Published: January 2010

AbstractObjective: The aim of this study was to evaluate osseointegration of one‐piece zirconia vs. titanium implants depending on their insertion depth by histomorphometry.Material and methods: Four one‐piece implants of identical geometry were inserted on each side of six mongrel dogs: (1) an uncoated zirconia implant, (2) a zirconia implant coated with a calcium‐liberating titanium oxide coating, (3) a titanium implant and (4) an experimental implant made of a synthetic material (polyetheretherketone). In a split‐mouth manner they were inserted in submerged and non‐submerged gingival healing modes. After 4 months, dissected blocks were stained with toluidine blue in order to histologically assess the bone‐to‐implant contact (BIC) rates and the bone levels (BL) of the implants.Results: All 48 implants were osseointegrated clinically and histologically. Histomorphometrically, BL in the crestal implant part did not differ significantly with regard to material type or healing modality. The submerged coated zirconia implants tended to offer the most stable crestal BL. The histometric results reflected the different healing modes by establishing different BL. The median BIC of the apical implant part of the zirconia and titanium group amounted to 59.2% for uncoated zirconia, 58.3% for coated zirconia, 26.8% for the synthetic material and 41.2% for titanium implants.Conclusions: Within the limits of this animal study, it is concluded that zirconia implants are capable of establishing close BIC rates similar to what is known from the osseointegration behaviour of titanium implants with the same surface modification and roughness. To cite this article:
Koch FP, Weng D, Krämer S, Biesterfeld S, Jahn‐Eimermacher A, Wagner W. Osseointegration of one‐piece zirconia implants compared with a titanium implant of identical design: a histomorphometric study in the dog. Clin. Oral Impl. Res. 21, 2010; 350–356. doi: 10.1111/j.1600‐0501.2009.01832.x
Transference of virtual planning and planning over biomedical prototypes for dental implant placement using guided surgery
Authors: Viegas Vinicius Nery , Dutra Vinicius , Pagnoncelli Rogério Miranda , De Oliveira Marília Gerhardt 
Published: January 2010

AbstractObjectives: This study evaluated the transference of virtual planning and planning over biomedical prototypes for dental implant placement using guided surgery.Material and methods: This experiment was conducted with 11 identical replicas of a human edentulous mandible. For each mandible, models and surgical guides were manufactured using stereolithography. Simulated surgeries were performed on the prototypes. Following this, the implants were placed in the mandible replicas. Superposition of the tridimensional pre‐ and postoperative models was used for virtual evaluation. The real evaluation was conducted by linear measurements directly on the models.Results: The variations in angles and distances between the coronal, central and apical regions of the 22 implants evaluated in this study had mean values <1.45° and 0.41 mm. The correlations between the positions of implant beds in each mandible were fair to very good, according to the distance analyzed and the interpretation guidelines used.Conclusions: According to the results of this study, the variations found in the transference of dental implant positioning to the operative field, determined during virtual planning and obtained in surgeries simulated with biomedical prototypes, confirm the reliability of guided surgery techniques in implantology. To cite this article:
Viegas VN, Dutra V, Pagnoncelli RM, de Oliveira MG. Transference of virtual planning and planning over biomedical prototypes for dental implant placement using guided surgery. Clin. Oral Impl. Res. 21, 2010; 290–295. doi: 10.1111/j.1600‐0501.2009.01833.x
Tolerance within a surgical guide
Authors: Van Assche N. , Quirynen M. 
Published: January 2010

Abstract:Background: Recently, guided surgery has been introduced and several papers verified its accuracy.Aim: While those studies reported on the accuracy of the entire procedure, this experiment wanted to make clinicians aware of the amount of the deviation that can already occur during the drilling procedure alone, due to the tolerance of the drill in the drill key.Material and methods: Drilling was executed in plexi‐glass with a maximal inclination of the drills within the drill keys.Results: A mean deviation in angulation of 4.7° occurred with a mean horizontal deviation at the implant shoulder of 0.8 mm and 1.8 mm at the apex of 13 mm implant. The deviation was further dependent of the implant length, the distance of the sleeve above the bone and the respective guiding system.Discussion: Increasing the height of the drill key will minimize the inaccuracy.Conclusions: The results from this experiment showed the importance of keeping the drill parallel to the guide in a centric position. To cite this article:
Van Assche N, Quirynen M. Tolerance within a surgical guide. Clin. Oral Impl. Res. 21, 2010; 455–458. doi: 10.1111/j.1600‐0501.2009.01836.x