bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Cavitand Supported Tetraphosphine: Cyclodextrin Offers a Useful Platform for Suzuki—Miyaura Cross‐Coupling.
Authors: Zaborova Elena , Deschamp Julia , Guieu Samuel , Bleriot Yves , Poli Giovanni , Menand Mickael , Madec David , Prestat Guillaume , Sollogoub Matthieu 
Published: November 2011

AbstractA new α‐cyclodextrin based tetraphosphine hybrid (CYTEP) is synthesized which displays exceptionally high TON (up to 340 000 000 000) and TOF numbers (up to 1 000 000 000 h‐1) in Suzuki—Miyaura coupling reactions.
ChemInform Abstract: Palladium‐Catalyzed Sonogashira Reactions of Aryl Amines with Alkynes via in situ Formation of Arenediazonium Salts.
Authors: Wu Xiao‐Feng , Neumann Helfried , Beller Matthias 
Published: November 2011

AbstractA novel protocol for the Pd‐catalyzed coupling of anilines with aromatic and aliphatic alkynes is described.
ChemInform Abstract: Gold‐Catalyzed Approach to Multisubstituted Fulvenes via Cycloisomerization of Furan/Ynes.
Authors: Chen Yifeng , Liu Yuanhong 
Published: November 2011

AbstractTreatment of enynes of type (III) and (VI) with AuCl(PPh3)/AgOTf in CH2Cl2 or THF allows a new and mild access to multisubstituted fulvenes bearing (E)‐ or (Z)‐alkene units.
ChemInform Abstract: Pd‐Catalyzed Cycloisomerization—Allylation of 4‐Alkynones: Synthesis of 5‐Homoallylfuran Derivatives.
Authors: Saito Akio , Enomoto Yohei , Hanzawa Yuji 
Published: November 2011

AbstractThe sequence affords 5‐homoallyl furans or dihydrofuran (V).
ChemInform Abstract: Chiral Biscinchona Alkaloid Promoted Asymmetric Allylic Alkylation of 3‐Substituted Benzofuran‐2(3H)‐ones with Morita—Baylis—Hillman Carbonates.
Authors: Liu Cong , Tan Bo‐Xuan , Jin Jia‐Lu , Zhang Yue‐Yan , Dong Nan , Li Xin , Cheng Jin‐Pei 
Published: November 2011

AbstractThe alkaloid efficiently promotes the coupling of 3‐substituted benzofuranones with carbonates giving 3,3‐disubstituted benzofuranones with moderate to high diastereo‐ and enantioselectivity.
ChemInform Abstract: Regioselective Oxidative Coupling Reactions of 3‐Substituted Thiophenes with Arylboronic Acids.
Authors: Schnapperelle Ingo , Breitenlechner Stefan , Bach Thorsten 
Published: November 2011

AbstractThe reaction of thiophene substrates bearing an ester or phosphonate groups proceeds with excellent regioselectivity at the C4 position.
ChemInform Abstract: o‐Iodoxybenzoic Acid (IBX): A Versatile Reagent for the Synthesis of N‐Substituted Pyrroles Mediated by β‐Cyclodextrin in Water.
Authors: Murthy S. Narayana , Nageswar Y. V. D. 
Published: November 2011

AbstractA new protocol allows the aromatization of various 1‐benzylpyrrolidines and L‐proline derivatives to afford the corresponding pyrroles.
ChemInform Abstract: A Facile Synthesis of Symmetrical and Unsymmetrical Bis(indolyl)acetamides Mediated by Protic Acid.
Authors: Shang Hai , Hao Fei‐Yue , Pan Li , Chen Hong , Cheng Mao‐Sheng 
Published: November 2011

AbstractDimerization of hydroxyindolylacetamides (I) and (V) leads to formation of symmetrical bis(indolyl)acetamides (II) and (VI), resp., while electrophilic substitution of indoles (III) and (VII) with indolylacetamides (I) give rise to unsymmetrical bis(indolyl)acetamides (IV) and (VIII).
ChemInform Abstract: Catalytic Enantioselective C—H Functionalization of Indoles with α‐Diazopropionates Using Chiral Dirhodium(II) Carboxylates: Asymmetric Synthesis of the (+)‐α‐Methyl‐3‐indolylacetic Acid Fragment of Acremoauxin A.
Authors: Goto Takayuki , Natori Yoshihiro , Takeda Koji , Nambu Hisanori , Hashimoto Shunichi 
Published: November 2011

AbstractThe title reaction provides a variety of N‐Mom‐protected α‐methyl‐3‐indolylacetates (III) in moderate enantioselectivities up to 86%.
ChemInform Abstract: Synthesis of Substituted 1,4,5,6‐Tetrahydrocyclopenta[b]pyrroles by Platinum‐Catalyzed Cascade Cyclization/Ring Expansion of 2‐Alkynyl‐1‐azaspiro[2.3]hexanes.
Authors: Yoshida Masahiro , Maeyama Yohei , Al‐Amin Mohammad , Shishido Kozo 
Published: November 2011

AbstractTetrahydroindoles like (XIV) are also available.
ChemInform Abstract: Tandem Indole C—H Alkenylation/Arylation for Tetra‐Substituted Alkene Synthesis.
Authors: Lopez Suarez Laura , Greaney Michael F. 
Published: November 2011

AbstractAlkynyl indoles such as (I), (IV), (VI) and (VIII) undergo a novel sequence of Pd‐catalyzed indole C—H activation/alkyne carbopalladation/arylation with diaryliodonium salts (II) furnishing the corresponding functionalized indole alkenes (III), (V), (VII) and (IX), resp., in good to high yields.
ChemInform Abstract: An Unexpected Result from the Reaction of Hydroxymethyl‐2‐oxazolidinones with Isocyanates.
Authors: Madesclaire M. , Leal F. , Weber V. , Decombat C. , Zaitsev V. P. , Zaitseva J. V. 
Published: November 2011

AbstractHydroxymethyl‐2‐oxazolidinones can react with aryl isocyanates at both the ring NH and OH‐group, unexpectedly.
ChemInform Abstract: Asymmetric Synthesis of Chiral δ‐Lactones Containing Multiple Contiguous Stereocenters.
Authors: Peed Jennifer , Dominguez Ignacio Perinan , Davies Iwan R. , Cheeseman Matt , Taylor James E. , Kociok‐Koehn Gabriele , Bull Steven D. 
Published: November 2011

AbstractThe cyclopropane ring opening reaction is mediated by Hg(O‐CO‐CF3)2, leads after demetalation to chiral δ‐lactones with multiple stereocenters.
ChemInform Abstract: Palladium‐Mediated Intramolecular Buchwald—Hartwig α‐Arylation of β‐Amino Esters: Synthesis of Functionalized Tetrahydroisoquinolines.
Authors: Reddy A Gopi Krishna , Krishna J. , Satyanarayana G. 
Published: November 2011

AbstractThe three‐step strategy involves reductive amination of aromatic aldehydes, addition of the resulting secondary amines to ethyl acrylate and final Buchwald—Hartwig cyclization.
ChemInform Abstract: Asymmetric Organocatalytic Synthesis of Complex Cyclopenta[b]quinoline Derivatives.
Authors: Jensen Kim L. , Dickmeiss Gustav , Donslund Bjarke S. , Poulsen Pernille H. , Joergensen Karl Anker 
Published: November 2011

AbstractVarious title systems bearing 5 stereogenic centers are prepared with excellent enantioselectivities in a one‐pot manner.
ChemInform Abstract: Synthesis of Furo[2,3‐c]pyridine.
Authors: Chang Meng‐Yang , Tai Hang‐Yi 
Published: November 2011

AbstractThe facile synthesis of furopyridine (VIII) is achieved in five steps from the known piperidinone (I) via Wittig olefination, intramolecular cyclization of (III) by treatment with Ph‐Se‐Cl, NaJO4‐mediated oxidative dehydroselenylation, furan ring formation by reduction, and finally, aromatization.
ChemInform Abstract: Investigating N‐Methoxy‐N′‐aryl Ureas in Oxidative C—H Olefination Reactions: An Unexpected Oxidation Behavior.
Authors: Willwacher Jens , Rakshit Souvik , Glorius Frank 
Published: November 2011

AbstractDihydroquinazolinones are prepared from a 2:1 stoichiometric ratio of ureas (I) or (IX) and acrylates or related olefins in the presence of a rhodium catalyst.
ChemInform Abstract: Three‐Component Tandem Reaction Involving Acid Chlorides, Terminal Alkynes, and Ethyl 2‐Amino‐1H‐indole‐3‐carboxylates: Synthesis of Highly Diversified Pyrimido[1,2‐a]indoles via Sequential Sonogashira and [3 + 3] Cyclocondensation Reactions.
Authors: Gupta Sahaj , Sharma Sudhir K. , Mandadapu Anil K. , Gauniyal Harsh M. , Kundu Bijoy 
Published: November 2011

AbstractAlkynone formation according to A) is followed by cyclocondensation according to B) to produce the heterocyclic system (IV)(18 examples).
ChemInform Abstract: A Practical Synthesis of Novel Rho‐Kinase Inhibitor, (S)‐4‐Fluoro‐5‐(2‐methyl‐1,4‐diazepan‐1‐ylsulfonyl)isoquinoline.
Authors: Gomi Noriaki , Ohgiya Tadaaki , Shibuya Kimiyuki , Katsuyama Jyunji , Masumoto Masayuki , Sakai Hitoshi 
Published: November 2011

AbstractThe synthesis of the novel inhibitor (VII) is achieved in multi‐kilogram scale overcoming two major issues: the need of developing a regioselective chlorosulfonylation reaction at C‐5 of fluoroisoquinoline and the stereochemical purity in the asymmetric construction of the methyldiazepane moiety.
ChemInform Abstract: Directed ortho‐Metalation—Cross Coupling Strategies. One‐Pot Suzuki Reaction to Biaryl and Heterobiaryl Sulfonamides.
Authors: Schneider Cedric , Broda Ellen , Snieckus Victor 
Published: November 2011

AbstractThe method is developed to prepare ortho‐boropinacolato aryl‐ and heteroaryl sulfonamides which can be used directly in one‐pot Suzuki couplings with aryl‐ and heteroaryl halides.
ChemInform Abstract: Ultrasound‐Assisted One‐Pot Synthesis of α‐Oxycarbanilinophosphonates via a Three‐Component Condensation of an Aldehyde, Diethyl Phosphite and an Isocyanate under Solvent‐Free Conditions.
Authors: Kaboudin Babak , Fallahi Maryam 
Published: November 2011

AbstractThe preparation of the synthetically important phosphonates becomes possible under mild conditions and no tar formation is observed.
ChemInform Abstract: A New Series of 2‐Alkoxy(aralkoxy)‐[1,2,4]triazolo[1,5‐a]quinazolin‐5‐ones as Adenosine Receptor Antagonists.
Authors: Al‐Salahi Rashad , Geffken Detlef , Koellner Maria 
Published: November 2011

AbstractAll compounds (I)‐(IV) are tested for their affinity at the adenosine receptor subtypes A1, A2A, and A2B.
Microstructures for the Catalytic Hydrogen Generation from Ethanol
Authors: Ehrich Heike , Jähnisch Klaus 
Published: November 2011

AbstractWasserstoff für Brennstoffzellensysteme wurde durch katalytische Wasserdampfreformierung von Ethanol in Mikrostrukturreaktoren erzeugt. Der Einfluss der Reaktionstemperatur, der Kontaktzeit und des molaren Steam/Carbon‐Verhältnisses (S/C) auf die Reaktion wurde untersucht. Der auf der Mikrostruktur beschichtete Co/ZnO‐Katalysator zeigte eine hohe Aktivität und Selektivität, die Wasserstoffausbeute betrug bis zu 5,2 mol mol–1 Ethanol. Ethanol wurde bei kurzer Kontaktzeit (W/F 25 g min mol–1) und 600 °C bei S/C‐Verhältnissen von 4,9 bis 6,5 vollständig umgesetzt.
A performance evaluation framework for packet scheduling algorithms in wireless system
Authors: Zhao X. , Liang H. 
Published: November 2011

SUMMARYThe question of how to evaluate wireless packet scheduling algorithms with a comprehensive consideration of different performance metrics is investigated in this paper. By studying the intrinsic relationship between system throughput and fairness, a performance evaluation problem for packet scheduling algorithms in a wireless system is formulated. Through the use of nonlinear programming method, the performance evaluation framework for weighted‐type packet scheduling algorithms can be established. The performances of some typical packet scheduling algorithms for multiuser wireless communications are also evaluated in this framework as examples. Copyright © 2011 John Wiley & Sons, Ltd.
CD304 is preferentially expressed on a subset of B‐lineage acute lymphoblastic leukemia and represents a novel marker for minimal residual disease detection by flow cytometry
Authors: Solly Françoise , Angelot Fanny , Garand Richard , Ferrand Christophe , Seillès Estelle , Schillinger Françoise , Decobecq Agnès , Billot Maryse , Larosa Fabrice , Plouvier Emmanuel , Deconinck Eric , Legrand Faezeh , Saas Philippe , Rohrlich Pierre‐Simon , Garnache‐Ottou Francine 
Published: November 2011

AbstractMinimal residual disease (MRD) has emerged as a major prognostic factor for monitoring patients with B‐lineage acute lymphoblastic leukemia (B‐ALL). The quantification of MRD by flow cytometry (FC) is based on the identification of a leukemia‐associated phenotype (LAP). Because phenotypic switch is common during treatment, multiple LAPs must be available and used for MRD detection over time. We evaluated the potential usefulness of CD304 as a new marker for monitoring MRD. CD304 was expressed in 48% of B‐ALL (24/50) with discriminative fluorescence intensity compared with CD304‐negative normal B‐cell precursors (n = 15). The sensitivity of CD304‐based MRD detection reached 10−4, as with some of established LAPs. The stability of CD304 expression evaluated during therapy and at relapse confirms the usefulness of this marker for MRD quantification. Finally, CD304 was repeatedly expressed in patients with TEL‐AML1 gene rearrangement, which warrants further investigation on its potential relevance as a prognosis marker or therapeutic target. © 2011 International Society for Advancement of Cytometry
Relaxor Behavior in a New Aurivillius Oxide – Bi2La0.5Sr0.5Nb1.75Sc0.25O9
Authors: Sivakumar Thathan , Itoh Mitsuru 
Published: November 2011

AbstractA new relaxor type n = 2 Aurivillius oxide material,Bi2La0.5Sr0.5Nb1.75Sc0.25O9 (I), containing heterovalent A and B site cations was synthesized by standard solid‐state reaction. The crystal structure of I was determined by Rietveld refinement of the powder X‐ray diffraction data in the polar A21am space group [a = 5.5152(5) Å, b = 5.5199(5) Å, c = 25.1982(12) Å; V = 767.12(10) Å3] at room temperature. Dielectric measurements for I reveal broad dielectric maxima that shift to higher temperature with increasing frequency. The dielectric maximum temperature (Tmax) at 100 kHz for I is 468 K, which is higher than that of the well‐known relaxor type Aurivillius oxide BaBi2Ta2O9. The relaxation parameter (γ), obtained from a modified Curie–Weiss law for I, is 1.91. The piezoelectric coefficient (d33) and remanent polarization (Pr) for the poled sample of I are 3 pC/N and 5.7 μC/cm2, respectively.
Development of a New Coated Graphite Phenylephrine Potentiometric Sensor and Its Applications to Pharmaceutical and Biological Analysis
Authors: Soleymanpour Ahmad , Abdifar Sorush , Bani Reza 
Published: November 2011

AbstractThe construction and performance characteristics of a coated graphite phenylephrine‐selective electrode based on incorporation of the ion‐association complex of phenylephrine‐tetraphenylborate in plasticized PVC matrix was studied. The electrode exhibited a Nernstian slope of 59.0 mV/decade to phenylephrine over a wide concentration range from 3.0×10−6 to 5.6×10−2 M with a low detection limit of 1.5×10−6 M. The proposed electrode manifested advantages of fast response, long life time and, most important, good selectivities for phenylephrine relative to a wide variety of common foreign inorganic cations, anions and also organic species. The electrode was successfully applied to determine phenylephrine in adult cold tablets, phenylephrine eye‐drops and also blood serum samples. The inclusion complex formation between α‐ and β‐cyclodextrine and phenylephrine was studied potentiometrically by the proposed electrode.
Rapid Flow Injection Electrochemical Detection of Arochlor 1242 Using Stabilized Lipid Membranes with Incorporated Sheep anti‐PCB Antibody
Authors: Michaloliakos Antonis I. , Nikoleli Georgia‐Paraskevi , Siontorou Christina G. , Nikolelis Dimitrios P. 
Published: November 2011

AbstractThis work describes a novel electrochemical biosensor based on a supported polymerized lipid film with incorporated Sheep anti‐PCB antibody for the rapid detection of arochlor 1242 in flowing solution streams. The antibody was incorporated into the lipid film during polymerization. Injections of antigen were made into flowing streams of a carrier electrolyte solution. Experiments were done in a stopped‐flow mode using lipid mixtures containing 15 % (w/w) dipalmitoylphosphatidic acid (DPPA) to provide only a single transient current signal with a magnitude related to the antigen concentration. Lipid films containing 35 % DPPA were used to examine regeneration of the active sites of antibody after complex formation by washing with the carrier electrolyte solution. Repetitive cycles of injection of antigen have shown that the maximum number of cycles is about 5.
Multioperational Oxidase Biosensors Based on Carbosilane Dendrimers with Interacting Ferrocenes
Authors: García Martínez M. , Alonso B. , Casado C. M. , Losada J. , García Armada M. P. 
Published: November 2011

AbstractThe bioelectrocatalytical properties and kinetic characteristics of new oxidase biosensors based on two different carbosilane dendrimers are described. The best glucose biosensor developed displayed, in an ascorbate interference free work potential interval, a strictly linear range from 0 to 4.0 mM, a detection limit of 40,6 μM and a response time less than 3 s. The lactate biosensor displayed a linear range from 0 to 0.8 mM, a detection limit of 0.73 µM and a response time less than 2 s. The apparent Michaelis–Menten constants were calculated to be 4.39 mM and 2.08 mM respectively, according to Lineweaver–Burk equation.
Removal of surfactant dodecylbenzenesulfonate by consecutive use of ozonation and biodegradation
Authors: Rivera‐Utrilla José , Bautista‐Toledo María I. , Sánchez‐Polo Manuel , Méndez‐Díaz José D. 
Published: November 2011

AbstractSuccessful surfactant removal from wastewater is often limited by the high concentration of the surfactant. The use of advanced oxidation processes can be the key to aid biological treatment of water containing high amounts of surfactants. The present study analyzes the biodegradation of the anionic surfactant sodium dodecylbenzenesulfonate (SDBS) and the effects of its combination with ozonation. SDBS pre‐ozonation favors the metabolism by microorganisms. Experimental results indicate that the application of a concentration of up to 60 μM of ozone for 60 min, prior to contact with microorganisms, increases the percentage of SDBS removed by biodegradation alone. These results demonstrate that the removal of SDBS and of the total organic carbon is increased by the consecutive use of ozonation and biodegradation.
Structural Magnetic Resonance Imaging in Eating Disorders: A Systematic Review of Voxel‐Based Morphometry Studies
Authors: Van den Eynde Frederique , Suda Masashi , Broadbent Hannah , Guillaume Sébastien , Van den Eynde Magali , Steiger Howard , Israel Mimi , Berlim Marcelo , Giampietro Vincent , Simmons Andrew , Treasure Janet , Campbell Iain , Schmidt Ulrike 
Published: November 2011

AbstractThis systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel‐based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta‐analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
Revisiting psychophysical work on the quantitative and qualitative odour properties of simple odour mixtures: a flavour chemistry view. Part 1: intensity and detectability. A review.
Authors: Ferreira Vicente 
Published: November 2011

ABSTRACTThe different psychophysical studies carried out on the quantitative properties of binary mixtures are reviewed. Results from 520 mixtures have been reprocessed and plotted together. The most likely outcome of a binary mixture of two different odorants at supra‐threshold levels is a significant reduction of its odour intensity not only with respect to the total addition of intensities, but also to what could be expected from an auto‐addition following Stevens's law. Half of the mixtures behave asymmetrically, so that one of the odorants can reduce the overall odour intensity of the mixture more efficiently than the other. This is most frequent when there is a marked difference in the hedonic character of the odorants, and the least pleasant odorant plays the role of suppressor. Such suppression can be quantitatively relevant. The addition of the third, fourth or fifth isointense constituent do not cause any further intensity increase, which indicates the existence of strong signal compression mechanisms at supra‐receptor level. Synergism is highly infrequent and may be linked to the appearance of new odour concepts. In the case of mixtures of sub‐threshold odorants, the oldest reports are based on the odour activity value concept, and, in general, show the existence of a certain degree of cooperation between the components of the mixture. The most recent research makes use of detectability functions and probabilistic considerations and has demonstrated that cooperation can be categorized as hypoaddition, perfect addition (independence of response) or even synergy. Hypoaddition is most frequent at higher concentrations. Some reports suggest that hypoaddition is related to the structural similarity but results are not conclusive. Other reports demonstrate that under or peri‐threshold odorants are able to introduce significant qualitative and quantitative changes on supra‐threshold odour solutions. So far it is not feasible to assess when and why this enhancing effect takes place. It can be hypothesized that the answer will require an integral treatment of quality and intensity. Copyright © 2011 John Wiley & Sons, Ltd.
Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation
Authors: Brekke Eva , Walls Anne B. , Nørfeldt Lasse , Schousboe Arne , Waagepetersen Helle S. , Sonnewald Ursula 
Published: November 2011

AbstractPyruvate carboxylation (PC) is thought to be the major anaplerotic reaction for the tricarboxylic acid cycle and is necessary for de novo synthesis of amino acid neurotransmitters. In the brain, the main enzyme involved is pyruvate carboxylase, which is predominantly located in astrocytes. Carboxylation leads to the formation of oxaloacetate, which condenses with acetyl coenzyme A to form citrate. However, oxaloacetate may also be converted to malate and fumarate before being regenerated. This pathway is termed the oxaloacetate‐fumarate‐flux or backflux. Carbon isotope‐based methods for quantification of activity of PC lead to underestimation when backflux is not taken into account and critical errors have been made in the interpretation of results from metabolic studies. This study was conducted to establish the degree of backflux after PC in cerebellar and neocortical astrocytes. Astrocyte cultures from cerebellum or neocortex were incubated with either [3‐13C] or [2‐13C]glucose, and extracts were analyzed using mass spectrometry or nuclear magnetic resonance spectroscopy. Substantial PC compared with pyruvate dehydrogenase activity was observed, and extensive backflux was demonstrated in both types of astrocytes. The extent of backflux varied between the metabolites, reaffirming that metabolism is highly compartmentalized. By applying our calculations to published data, we demonstrate the existence of backflux in vivo in cat, rat, mouse, and human brain. Thus, backflux should be taken into account when calculating the magnitude of PC to allow for a more precise evaluation of cerebral metabolism. © 2011 Wiley Periodicals, Inc.