bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deleuze’s zeroness and Peirce’s pure zero regarding the expansion of semiotics’ categorial frame
Authors: Cardoso Jr. Helio Rebello 
Published: April 2024

Abstract
Deleuze (1925–1995), in the early 1980s, adopts Peirce’s (1839–1914) semiotics in order to classify the signs that the images of the cinema display. Aiming at insufflating the Peircean principles with the movement that animates the images of cinema, he provides Peirce’s triadic logic with a new category – Zeroness – which stands for the semiotic movement of cinematic images. Deleuze’s new category has impacts on the main domains of Peirce’s philosophy. Accordingly, our inquiry will focus on the irradiation of Zeroness over the (a) system of categories, the (b) Peircean phenomenology (phaneroscopy), the (c) generative categorial role, the (d) semiotic effectiveness, the (e) doctrine of continuity, and the (f) logic of relatives. This article will show that for Deleuze nearly like more recent Peircean scholarship: (a) zeroth state holds a categorial status, (b) some phenomenon instantiates zeroth state, (c) zeroth state plays a generative role regarding Peirce's categories, (d) zeroth state as a phenomenological category is semiotically effective, (e) zeroth state and the doctrine of continuity, and (f) zeroth state is a “medad.” In order to assess these topics, we recover Deleuze’s advances on Peirce’s philosophy and confront them with the Peircean studies on the zeroth state. Finally, we will see that Deleuze, far from being a Peircean scholar, developed the importance of the zeroth state for Peirce’s semiotics in advance to the subsequent Peircean scholarship. Reciprocally, most of Deleuzian scholars understimate the importance of Peirce for Deleuze’s semiotics.
Study on modified graphene oxide-based emulsion cleaner for oily sludge
Authors: Zheng Shuang , Li Xin , Chen Yang , Zhu Rongjiao , Feng Xia 
Published: April 2024

Abstract
Oily sludge is a complex system that is inevitably generated during the process of oil extracting and processing. It will cause serious environmental pollution and waste of resources if untreated sludge is discharged. In this paper, a composite emulsion cleaner based on modified graphite oxide and surfactants was developed for cleaning oily sludge. First, graphite oxide (GO) was functionally modified with butylamine, and its structures were verified by Fourier transform infrared spectroscopy (FTIR), X-ray electron spectroscopy (XPS), thermogravimetric analysis (TGA), and environmental scanning electron microscopy (SEM). Then, the oil-in-water composite emulsion cleaner was prepared by using butylamine modified graphite oxide and surfactants. The conditions for emulsion preparation and oil sludge cleaning were modelled and optimized by the response surface methodology. The obtained optimal formulations were: surfactant content was 2.17 ‰ with SDS/AEO-3 ratio of 9:1, GO-A4 content was 0.96 ‰, water-oil ratio was 5:5, and the oil removal rate was 97.45 %. The optimal cleaning conditions were: liquid-solid ratio of 3.2:1, cleaning time of 32 min, cleaning temperature of 28.7 °C, and oil removal rate of 99.02 %. The solid sediments were characterized by FTIR and SEM, which proved the feasibility of cleaning oily sludge with the emulsion.
Association between weight-adjusted-waist index and depression: a cross-sectional study
Authors: Fei Sun , Liu Min , Shanshan Hu , Xie Ruijie , Danni Wu , Ningying Zhou 
Published: April 2024

Background
Depression has become a multifaceted global health issue, with complex connections to obesity. Weight-adjusted-waist index (WWI) can effectively evaluate central obesity, but the relationship between WWI and depression has not been well studied. The study aims to investigate the potential correlation between these two health parameters.

Methods
According to the data from National Health and Nutrition Examination Survey, this cross-sectional study used multiple regression analysis, subgroup analysis, and smooth curve fitting to explore the relationship between WWI and depression. The assessment ability of WWI was evaluated and compared to other obesity indicators using the receiver operating characteristic (ROC) curve.

Results
This study analyzed 38,154 participants. Higher WWI is associated with higher depression scores (β = 0.41; 95% CI, 0.36–0.47). After adjusting for various confounding factors, the positive correlation between WWI and depression remained significant (P for trend < 0.0001). Nonlinear positive correlation was detected with a breakpoint of 11.14. ROC analysis shows that compared to other obesity indicators (ROCWWI = 0.593; ROCBMI = 0.584; and ROCWC = 0.581), the correlation between WWI and depression has better discrimination and accuracy. DII mediated 4.93%, SII mediated 5.08%, and sedentary mediated 0.35% of the total association between WWI and depression.

Conclusion
WWI levels were related to an increased likelihood of depression and showed a stronger relationship than BMI and waist circumference. Our findings indicated that WWI may serve as a simple anthropometric index to evaluate depression.
Pro-opiomelanocortin and ACTH–cortisol dissociation during pediatric cardiac surgery
Authors: Téblick Arno , Vanhorebeek Ilse , Derese Inge , Jacobs An , Haghedooren Renata , Maebe Sofie , Zeilmaker-Roest Gerdien A , Wildschut Enno D , Langouche Lies , Van den Berghe Greet 
Published: April 2024

In critically ill adults, high plasma cortisol in the face of low ACTH coincides with high pro-opiomelanocortin (POMC) levels. Glucocorticoids further lower ACTH without affecting POMC. We hypothesized that in pediatric cardiac surgery-induced critical illness, plasma POMC is elevated, plasma ACTH transiently rises intraoperatively but becomes suppressed post-operatively, and glucocorticoid administration amplifies this phenotype. From 53 patients (0–36 months), plasma was obtained pre-operatively, intraoperatively, and on post-operative days 1 and 2. Plasma was also collected from 24 healthy children. In patients, POMC was supra-normal pre-operatively (P < 0.0001) but no longer thereafter (P > 0.05). ACTH was never high in patients. While in glucocorticoid-naive patients ACTH became suppressed by post-operative day 1 (P < 0.0001), glucocorticoid-treated patients had already suppressed ACTH intraoperatively (P ≤ 0.0001). Pre-operatively high POMC, not accompanied by increased plasma ACTH, suggests a centrally activated HPA axis with reduced pituitary processing of POMC into ACTH. Increasing systemic glucocorticoid availability with glucocorticoid treatment accelerated the suppression of plasma ACTH.

Significance statement
Glucocorticoids are often administered during pediatric cardiac surgery. In critically ill children, endogenous systemic glucocorticoid availability is elevated already upon ICU admission while ACTH levels are normal. This hormonal constellation suggests the presence of active feedback inhibition of ACTH. In this study, we have documented that intraoperative administration of glucocorticoids accelerates the suppression of ACTH, resulting in low plasma ACTH already upon ICU admission. Pre-operative plasma POMC, the ACTH precursor, but not ACTH, was increased. This is compatible with a centrally activated HPA axis prior to surgery in young children but reduced processing of POMC into ACTH within the pituitary. These findings suggest that glucocorticoid treatment in the context of pediatric cardiac surgery may amplify pre-existing impaired pituitary processing of the prohormone POMC.
Community perspectives on COVID-19 outbreak and public health: Inuit positive protective pathways and lessons for Indigenous public health theory
Authors: Healey Akearok Gwen K. , Rana Zoha 
Published: April 2024

Abstract
Objectives
Indigenous public health theory and the voices of Canadian Indigenous communities remain under-represented in the literature despite the Canadian Truth and Reconciliation Calls to Action, and the perspectives of Inuit are further under-represented in this literature. The goal of this paper is to explore the perspectives of Iqalungmiut (people of Iqaluit), frontline staff, and decision-makers on the management of the COVID-19 outbreak in Iqaluit in April to June 2021 and to identify lessons learned and contributions to public health policy and practice specific to Inuit populations in Canada.

Methods
This study used the Piliriqatigiinniq Community Health Research Model which was developed by Nunavummiut to guide community-based health and well-being research. Interviews were conducted with 44 individuals: 22 community members and shelter users; 17 frontline workers; and 5 decision-makers representing municipal and territorial government. Participants were asked about their experiences during the outbreak, sources of information, and strengths and challenges during outbreak management.

Results
Challenges included overcrowding, physical disconnection from family members, and mental health and trauma. Community-identified strengths included strong interagency cooperation, food hamper and COVID-19 care kit deliveries, and travel restrictions. Several Inuit positive health-protective pathways were identified including
"Image missing"Ilaginniq;
"Image missing"Silativut;
"Image missing"Inuuqatigiittiarniq;
"Image missing"Piliriqatigiinniq;
"Image missing"Ikajurniq; and
"Image missing"Pijitsirniq.

Conclusion
Outbreaks of infectious illness are not new to Nunavut communities and Inuit protective pathways have and continue to be critical avenues to adapt to and mitigate such challenges. This exploratory study provides clear direction for Inuit public health policy and practice in Canada, while contributing to the body of literature on Indigenous public health theory.
Intercultural Interaction of Russian and Foreign Students: Major Categories in the Problem Area of Pedagogical Research
Authors: Ильязова М.Д. , Абдуллаева А.С. , Айналиева А.Р. 
Published: April 2024

Организация совместной деятельности студентов – представителей разных стран и разных культур требует создания образовательной среды, построенной на принципах толерантности. Исследование педагогических условий организации межкультурного взаимодействия российских и иностранных студентов в образовательном пространстве вуза – актуальная задача. Определены ключевые категории, которые образуют проблемное поле таких исследований: «межкультурное взаимодействие», «педагогическая ситуация межкультурного взаимодействия», «межкультурная толерантность студента». Выявлены основания для определения содержания понятия «межкультурная толерантность студента». Представлено определение понятия «толерантное поведение субъекта межкультурного взаимодействия». В структуре межкультурной толерантности студента выделаны компоненты – когнитивный, аффективный и конативный. Определены два класса педагогических условий формирования межкультурной толерантности студентов.
Organizing joint activities of students representing different countries and different cultures requires the creation of an educational environment built on the principles of tolerance. The study of pedagogical conditions for organizing intercultural interaction between Russian and foreign students in the educational space of a university is an urgent task. The key categories that form the problem field of such research are identified: “intercultural interaction”, “pedagogical situation of intercultural interaction”, “student’s intercultural tolerance”. The grounds for determining the content of the concept “intercultural tolerance of a student” have been identified. A definition of the concept of “tolerant behavior of a subject of intercultural interaction” is presented. The structure of a student’s intercultural tolerance includes components – cognitive, affective and conative. Two classes of pedagogical conditions for the formation of intercultural tolerance among students have been identified.
Students’ Attestation in Modern Conditions: From Increasing the Effectiveness of Assessment to Trusting Assessments
Authors: Малыгин А.А. 
Published: April 2024

Смена парадигмы в высшем образовании, переход на компетентностно ориентированные образовательные стандарты заставляют переосмысливать аттестационные процедуры, по результатам которых делаются выводы о качестве образования и принимаются управленческие решения. Законодательные требования соблюдения принципов объективности и независимости при итоговой аттестации студентов возможно достичь, если обратиться к методологии образовательных измерений, повышая эффективность оценочных процедур и обеспечивая справедливость и доверие к их результатам. В отличие от традиционных форматов проведения государственного экзамена на итоговой аттестации предлагаемое адаптивное оценивание привлекательно с позиций получения точных оценок об уровне подготовленности или сформированности компетенций студентов за счет оптимизации количества заданий и создания «ситуации успеха» для каждого аттестуемого в процессе измерения. Такой подход позволяет также реализовать гуманистические цели контрольно-оценочной деятельности в образовании.
A paradigm shift in higher education, the transition to competency-based educational standards, forces us to rethink certification procedures, based on the results of which conclusions are drawn about the quality of education and management decisions are made. Legislative requirements for observing the principles of objectivity and independence in the final assessment of students can be achieved by turning to the methodology of educational measurements, increasing the efficiency of assessment procedures and ensuring fairness and trust in their results. In contrast to traditional formats for conducting a state exam at the final certification, the proposed adaptive assessment is attractive from the standpoint of obtaining accurate assessments of the level of preparedness or maturity of students’ competencies by optimizing the number of tasks and creating a “success situation” for each person being certified in the measurement process. This approach also makes it possible to realize the humanistic goals of control and evaluation activities in education.
Strengthening digital transformation in adult education organisations
Authors: Gródek-Szostak Zofia , Niemczyk Agata , Siguencia Luis Ochoa , Suder Marcin , Handzel Jarosław A. 
Published: April 2024

Social inclusion is an important aspect of any society as it helps to create a sense of belonging and togetherness. It allows individuals to form meaningful relationships with others, while enabling them to make a meaningful contribution to their local communities. Social inclusion has many benefits that can help improve the well-being of both the included and the excluded. One of the benefits of social inclusion is increased access to resources such as education, healthcare, employment opportunities, and other basic needs that may be difficult or impossible for some people to access without community or peer support.
By providing these resources through community programmes like mentoring initiatives or job training, individuals are more likely to succeed than if they were left on their own without the help of others. Additionally, this support often leads to improved mental health outcomes due to increased self-esteem. Another benefit associated with social inclusion is the reduction of stigma around certain problems, such as poverty or homelessness, by promoting understanding between different social groups. When members of marginalised groups are able to participate fully in mainstream activities, they feel accepted despite their differences from the majority of society, leading to greater empathy on both sides.
This article presents experiences from the project Empower adult educators to support digital social inclusion 2022-1-PL01-KA220-ADU-000088404 [DigIN Project], which aims to improve the capacity of educators and adult education organisations to support them in becoming active users of technology.
DPA-2: Towards a universal large atomic model for molecular and materials simulation
Authors: Wang Han , Zhang Duo , Liu Xinzijian , Zhang Xiangyu , Zhang Chengqian , Cai Chun , Bi Hangrui , Du Yiming , Qin Xuejian , Huang Jiameng , Li Bowen , Shan Yifan , Zeng Jinzhe , Zhang Yuzhi , Liu Siyuan , Li Yifan , Chang Junhan , Wang Xinyan , Zhou Shuo , Liu Jianchuan , Luo Xiaoshan , Wang Zhenyu , Jiang Wanrun , Wu Jing , Yang Yudi , Yang Jiyuan , Yang Manyi , Gong Fu-Qiang , Zhang Linshuang , Shi Mengchao , Dai Fu-Zhi , York Darrin , Liu Shi , Zhu Tong , Zhong Zhicheng , Lv Jian , Cheng Jun , Jia Weile , Chen Mohan , Ke Guolin , E Weinan , Zhang Linfeng 
Published: April 2024

Abstract

The rapid development of artificial intelligence (AI) is driving significant changes in the field of atomic modeling, simulation, and design. AI-based potential energy models have been successfully used to perform large-scale and long-time simulations with the accuracy of ab initio electronic structure methods. However, the model generation process still hinders applications at scale. We envision that the next stage would be a model-centric ecosystem, in which a large atomic model (LAM), pre-trained with as many atomic datasets as possible and can be efficiently fine-tuned and distilled to downstream tasks, would serve the new infrastructure of the field of molecular modeling. We show that DPA-2 can accurately represent a diverse range of chemical systems and materials, enabling high-quality simulations and predictions with significantly reduced efforts compared to traditional methods. Our approach paves the way for a universal large atomic model that can be widely applied in molecular and material simulation research, opening new opportunities for scientific discoveries and industrial applications.
Experimental study of Adsorption Performance on Single layer Desiccant Materials
Authors: Balthazar Pravinth , Hwa Yu Kok , Ismail Mohd Azmi 
Published: April 2024

Abstract

This paper presents an experimental study of the adsorption performance of a solid desiccant pack porous bed. Activated alumina, Desiccant clay, and Silica gel are arranged as single-layer desiccant beds. Experiments have been conducted under warm and humid climate conditions and for various Reynolds numbers between 5300 and 18600. Activated alumina, Silica gel, and Desiccant clay show 5.4, 4.6, and 3.4 times higher adsorption coefficients at Reynolds number 18,600 than at Reynolds number 5,300. The adsorption coefficient is inversely proportional to time and Reynolds number irrespective of climate conditions and desiccant materials. Silica gel adsorbed the highest humidity under warm, humid climate conditions compared to Activated alumina and Desiccant clay. However, Desiccant clay is the most energy-efficient moisture adsorption material for Reynolds numbers lower than 12000, and the contrary is applicable for Silica gel. Silica gels’ pressure drop is, on average, 29.6% and 51.9% higher than Activated alumina and Desiccant clay.
Soybean residues assisted g-C3N4/SiC photocatalyst prepared from waste materials: Synthesis, characterization, and application of tetracycline photodegradation irradiated with simulated sunlight
Authors: Dai Yung-Dun , Chou You-Lin , Hung Chung-Hsuang , Yuan Ching 
Published: April 2024

Abstract

This study employed the reproduced carbon black, waste silicon materials, and soybean residue to develop an environmentally friendly O-gC3N4/SiC composite photocatalyst and evaluated the corresponding photodegradation performance of tetracycline (TC). Initially, the reproduced carbon black was soaked in nitric acid to eliminate impurities, which resulted in the lowest ash content (7.86%). Soybean residue is a vital replacement for melamine during the preparation of graphitic carbon nitride. The characteristics of the synthesized SiC, O-gC3N4, and O-gC3N4/SiC photocatalysts were verified through TEM, XRD, and Fourier-transform infrared spectroscopy. The characteristic wavelength of the O-gC3N4/SiC photocatalysts was 523–541 nm, indicating that visible light triggers the photocatalytic reaction. The composites of soybean residue and SiC enhanced TC degradation, resulting in the best degradation rate of 89.5% with an initial first-order reaction rate constant of 2.01 × 10− 2 1/min for O0.10M0.90SC5 photocatalysts. Free radical trapping experiments determined the electron holes (h+) and OH· as the primary free radicals responsible for TC degradation, whereas O2−· played a relatively minor role. A photodegradation mechanism for O-gC3N4/SiC was also proposed. The prepared O-gC3N4/SiC photocatalysts are promising candidates for sustainable applications.
miR-340-3p-modified bone marrow mesenchymal stem cell-derived exosomes inhibit ferroptosis through METTL3-mediated m6A modification of HMOX1 to promote recovery of injured rat uterus
Authors: Yang Fu , xiao bang , Zhu Yiqing , Liu Meng , Chen Meiting , Huang Chao , Xu Dabing , Wang Fang , Sun Shuhan , Huang Jinfeng , Sun Ningxia 
Published: April 2024

Abstract

Background
Ferroptosis is associated with the pathological progression of hemorrhagic injury and ischemia-reperfusion injury. According to our previous study, exosomes formed through bone marrow mesenchymal stem cells modified with miR-340-3p (MB-exos) can restore damaged endometrium. However, the involvement of ferroptosis in endometrial injury and the effect of MB-exos on ferroptosis remain elusive.
Methods
The endometrial injury rat model was developed. Exosomes were obtained from the supernatants of BMSCs and miR-340/BMSCs through differential centrifugation. We conducted RNA-seq analysis on endometrial tissues obtained from the PBS and MB-exos groups. Ferroptosis was induced in ESCs by treating them with erastin or RSL3, followed by treatment with B-exos or MB-exos. We assessed the endometrial total m6A modification level after injury and subsequent treatment with B-exos or MB-exos by methylation quantification assay. We performed meRIP-qPCR to analyze m6A modification-regulated endogenous mRNAs.
Results
We reveal that MB-exos facilitate the injured endometrium to recover by suppressing ferroptosis in endometrial stromal cells. The injured endometrium showed significantly upregulated N6-methyladenosine (m6A) modification levels; these levels were attenuated by MB-exos through downregulation of the methylase METTL3. Intriguingly, METTL3 downregulation appears to repress ferroptosis by stabilizing HMOX1 mRNA, thereby potentially elucidating the mechanism through which MB-exos inhibit ferroptosis in ESCs. We identified YTHDF2 as a critical m6A reader protein that contributes to HMOX1 mRNA degradation. YTHDF2 facilitates HMOX1 mRNA degradation by identifying the m6A binding site in the 3ʹ-untranslated regions of HMOX1. In a rat model, treatment with MB-exos ameliorated endometrial injury-induced fibrosis by inhibiting ferroptosis in ESCs. Moreover, METTL3 short hairpin RNA-mediated inhibition of m6A modification enhanced the inhibitory effect of MB-exos on ferroptosis in endometrial injury.
Conclusions
Thus, these observations provide new insights regarding the molecular mechanisms responsible for endometrial recovery promotion by MB-exos and highlight m6A modification-dependent ferroptosis inhibition as a prospective therapeutic target to attenuate endometrial injury.