bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of integrating mowing and systemic herbicides applied with a weed wiper for Sporobolus indicus var. pyramidalis management in Florida
Authors: Dias Jose C.L.S. , Mncube Temnotfo L. , Sellers Brent A. , Ferrell Jason A. , Enloe Stephen F. , Vendramini Joao M.B. , Moriel Philipe 
Published: May 2024

AbstractGiant smutgrass [Sporobolus indicus (L.) R. Br. var. pyramidalis (P. Beauv.) Veldkamp] is an invasive species in grasslands, and herbicide application has been the most efficient management method to suppress this weed. Experiments were conducted in 2017 and 2018 to determine the effects of wiping glyphosate and hexazinone on S. indicus var. pyramidalis. A dose–response experiment using a handheld weed wiper was established with 20 treatments comprising two herbicides (glyphosate and hexazinone), uni- and bidirectional wiping methods, and 5 herbicide concentrations (6.25% v/v, 12.5% v/v, 25.0% v/v, 50.0% v/v, and 100% v/v basis). Data were collected 30 and 60 d after treatment (DAT). An ATV-mounted roto-type weed-wiper experiment was established in a strip-plot arrangement, with mowing as the horizontal strip, the wiping method (unidirectional vs. bidirectional) randomized as the vertical strip with three dosages of each herbicide for a total of 12 wiping treatments. Data were collected at 35 and 90 DAT. The percent plant mortality was calculated using differences in pre- and posttreatment plant counts. ANOVA and log-logistic linear regression were used to analyze the data. The dose–response experiment showed that S. indicus var. pyramidalis mortality increased with herbicide concentration, and mortality was greater with the bidirectional wiping method compared with the unidirectional method. Treatments wiped bidirectionally with glyphosate at 70% v/v, hexazinone at 30% v/v, and hexazinone at 60% v/v resulted in S. indicus var. pyramidalis mortality ranging from 75% to 98% by 90 DAT across all locations. The ATV-mounted weed-wiper experiment showed that mowing before herbicide application with weed wipers decreased the efficacy of both herbicides. Overall, both experiments indicate that S. indicus var. pyramidalis should be wiped bidirectionally using either glyphosate (70% v/v) or hexazinone (at least 30% v/v) to obtain satisfactory control. Further work should be conducted to determine whether seasonality impacts the response of S. indicus var. pyramidalis to mowing and the application of these herbicides.
Depressive symptoms in adolescence and adult educational and employment outcomes: a structured life course analysis
Authors: López-López José A. , Tilling Kate , Pearson Rebecca M. , Fazel Mina S. , Washbrook Elizabeth , Zhu Yiwen , Smith Brooke J. , Dunn Erin C. , Smith Andrew D. A. C. 
Published: May 2024

AbstractBackgroundDepression is a common mental health disorder that often starts during adolescence, with potentially important future consequences including ‘Not in Education, Employment or Training’ (NEET) status.MethodsWe took a structured life course modeling approach to examine how depressive symptoms during adolescence might be associated with later NEET status, using a high-quality longitudinal data resource. We considered four plausible life course models: (1) an early adolescent sensitive period model where depressive symptoms in early adolescence are more associated with later NEET status relative to exposure at other stages; (2) a mid adolescent sensitive period model where depressive symptoms during the transition from compulsory education to adult life might be more deleterious regarding NEET status; (3) a late adolescent sensitive period model, meaning that depressive symptoms around the time when most adults have completed their education and started their careers are the most strongly associated with NEET status; and (4) an accumulation of risk model which highlights the importance of chronicity of symptoms.ResultsOur analysis sample included participants with full information on NEET status (N = 3951), and the results supported the accumulation of risk model, showing that the odds of NEET increase by 1.015 (95% CI 1.012–1.019) for an increase of 1 unit in depression at any age between 11 and 24 years.ConclusionsGiven the adverse implications of NEET status, our results emphasize the importance of supporting mental health during adolescence and early adulthood, as well as considering specific needs of young people with re-occurring depressed mood.
TWISTED ACTIONS ON COHOMOLOGIES AND BIMODULES
Authors: SHCHIGOLEV VLADIMIR 
Published: May 2024

AbstractFor closed subgroups L and R of a compact Lie group G, a left L-space X, and an L-equivariant continuous map
$A:X\to G/R$
, we introduce the twisted action of the equivariant cohomology
$H_R^{\bullet }(\mathrm {pt},\Bbbk )$
on the equivariant cohomology
$H_L^{\bullet }(X,\Bbbk )$
. Considering this action as a right action,
$H_L^{\bullet }(X,\Bbbk )$
becomes a bimodule together with the canonical left action of
$H_L^{\bullet }(\mathrm {pt},\Bbbk )$
. Using this bimodule structure, we prove an equivariant version of the Künneth isomorphism. We apply this result to the computation of the equivariant cohomologies of Bott–Samelson varieties and to a geometric construction of the bimodule morphisms between them.
Temporal Pattern and Profile of a Coastal‐Deep Sea Conveyor at a Marginal Deep Oligotrophic Sea
Authors: Alkalay Ronen , Weinstein Yishai , Herut Barak , Ozer Tal , Zlatkin Olga , Bar Tslil , Berman‐Frank Ilana , Katz Timor 
Published: May 2024

AbstractSediment trap data set and 234Th profiles (deep water excesses and deficits) reveal that particulate organic carbon (POC) export at the highly oligotrophic Levantine Sea is dominated by lateral transport from the nearby margin. These intermediate nepheloid layers (INL) operate at multi‐depth, with the silt‐to‐clay size particulate matter (PM) fraction transported at water depths of about 100–500 m, while finer fraction arrives also at deeper depths. The shallow NIL is triggered by winter storms, manipulated by coastal flash floods and shelf resuspension and assisted by cross‐shore currents, which allow the arrival of PM at a distance of 50 km within about 10 days. The deeper INL could be related to sediments initially driven to depth by density currents. Our data show that inter‐annual differences in sediment trap fluxes were related to changes in both the intensity of coastal floods and current velocity. The frequent observation of deep‐water 234Th excesses during a (relatively) low export winter (2018) is related to lessened cleansing of the water column, that is, reduced removal of fine‐grained PM by sinking coarser‐grained material. These observations highlight the importance of winter storm intensity in the POC budget of marginal seas like the Levantine Basin (LB) even in areas with limited river discharge. This further suggests that the anticipated increase in extreme weather events due to the on‐going climate change should have an impact on this coastal‐deep sea conveyor and on POC export in the LB.
Evaluation of Precipitation Forecast by the Operational China Meteorological Administration Mesoscale Model During the 2020 Meiyu Period
Authors: Shi Wenru , Zhu Kefeng , Li Xin , Zhang Bing 
Published: May 2024

AbstractThis study evaluated the precipitation forecast produced by the operational China Meteorological Administration Mesoscale model (CMA‐MESO) during the “super violent” Meiyu season of 2020. Generally, CMA‐MESO, which runs with ∼3‐km‐grid resolution, is able to reproduce the distribution and diurnal variation of precipitation. However, the precipitation amount is greatly overestimated, especially in eastern coastal areas of China. Precipitation in that region usually occurs with two peaks: one in the morning that mostly reflects organized precipitation systems, and the other in the afternoon generated mostly by local convection. Analyses showed that overestimation of low‐level wind speed is the main reason for the overestimation of precipitation. CMA‐MESO produces low‐level winds that are overly strong, which greatly enhance the predicted convergence at night, leading to overestimation of precipitation. Additionally, the stronger wind speed increases the estimated transport of water vapor to the eastern coastal area, producing fake convection near the coastal mountains as the perturbed wind direction turns toward the mountain area in the afternoon. In comparison with ERA5, CMA‐MESO tends to overestimate (underestimate) the temperature in the northwest (southeast), and the larger temperature gradient increases the pressure gradient, resulting in the stronger low‐level wind speed.
Mutations in the U4 snRNA gene RNU4-2 cause one of the most prevalent monogenic neurodevelopmental disorders
Authors: Greene Daniel , Thys Chantal , Berry Ian R. , Jarvis Joanna , Ortibus Els , Mumford Andrew D. , Freson Kathleen , Turro Ernest 
Published: May 2024

AbstractMost people with intellectual disability (ID) do not receive a molecular diagnosis following genetic testing. To identify new etiologies of ID, we performed a genetic association analysis comparing the burden of rare variants in 41,132 noncoding genes between 5,529 unrelated cases and 46,401 unrelated controls. RNU4-2, which encodes U4 small nuclear RNA, a critical component of the spliceosome, was the most strongly associated gene. We implicated de novo variants among 47 cases in two regions of RNU4-2 in the etiology of a syndrome characterized by ID, microcephaly, short stature, hypotonia, seizures and motor delay. We replicated this finding in three collections, bringing the number of unrelated cases to 73. Analysis of national genomic diagnostic data showed RNU4-2 to be a more common etiological gene for neurodevelopmental abnormality than any previously reported autosomal gene. Our findings add to the growing evidence of spliceosome dysfunction in the etiologies of neurological disorders.
Advancements in polyol synthesis: expanding chemical horizons and Néel temperature tuning of CoO nanoparticles
Authors: Baričić Miran , Nuñez Jorge M. , Aguirre Myriam H. , Hrabovsky David , Seydou Mahamadou , Meneghini Carlo , Peddis Davide , Ammar Souad 
Published: May 2024

AbstractThe polyol synthesis of CoO nanoparticles (NPs) is typically conducted by dissolving and heating cobalt acetate tetrahydrate and water in diethylene glycol (DEG). This process yields aggregates of approximately 100 nm made of partially aligned primary crystals. However, the synthesis demands careful temperature control to allow the nucleation of CoO while simultaneously preventing reduction, caused by the activity of DEG. This restriction hinders the flexibility to freely adjust synthesis conditions, impeding the ability to obtain particles with varied morpho-structural properties, which, in turn, directly impact chemical and physical attributes. In this context, the growth of CoO NPs in polyol was studied focusing on the effect of the polyol chain length and the synthesis temperature at two different water/cations ratios. During this investigation, we found that longer polyol chains remove the previous limits of the method, allowing the tuning of aggregate size (20–150 nm), shape (spherical-octahedral), and crystalline length (8–35 nm). Regarding the characterization, our focus revolved around investigating the magnetic properties inherent in the synthesized products. From this point of view, two pivotal findings emerged. Firstly, we identified small quantities of a layered hydroxide ferromagnetic intermediate, which acted as interference in our measurements. This intermediate exhibited magnetic properties consistent with features observed in other publications on CoO produced in systems compatible with the intermediate formation. Optimal synthetic conditions that prevent the impurity from forming were found. This resolution clarifies several ambiguities existing in literature about CoO low-temperature magnetic behavior. Secondly, a regular relationship of the NPs' TN with their crystallite size was found, allowing us to regulate TN over ~ 80 K. For the first time, a branching was found in this structure-dependent magnetic feature, with samples of spheroidal morphology consistently having lower magnetic temperatures, when compared to samples with faceted/octahedral shape, providing compelling evidence for a novel physical parameter influencing the TN of a material. These two findings contribute to the understanding of the fundamental properties of CoO and antiferromagnetic materials.
Linking periodontitis with 20 cancers, emphasis on oropharyngeal cancer: a Mendelian randomization analysis
Authors: Xiong Jun , Liu Hao , Li Conghua , Li Yong , Feng Jiali 
Published: May 2024

AbstractWhile associations between periodontitis and an elevated risk of cancer have been suggested, the results of existing observational studies have been inconsistent, also leaving room for further investigation into the underlying mechanisms. This study was designed to delve into the possible causal link between periodontitis and 20 standard cancers while concurrently identifying potential mediators. We initiated a Mendelian randomization analysis that drew from either publicly accessible or personally obtained genome-wide association study (GWAS) datasets. The inverse variance weighting (IVW) method served as our primary tool for analysis. To ensure the strength and consistency of our results, we implemented additional strategies, including weighted median, weighted mode, MR-Egger regression, and MR pleiotropy residual sum and outlier (MR-PRESSO), bolstered by funnel plots. Our analysis unveiled an elevated risk of head and neck cancer concomitant with periodontitis (p = 0.041, OR 0.999, 95% CI 0.999–1.000), specifically a heightened risk of oropharyngeal cancer (p = 0.022, OR 0.999, 95% CI 0.999–1.000). As a result of probing into potential mediators, Fusobacterium nucleatum emerged as a likely intermediary in the promoting effect of periodontitis on oropharyngeal cancer (p = 0.021, OR 0.999, 95% CI 0.998–1.000). Inversely, basal cell carcinoma and endometrial cancer demonstrated an association with an increased incidence of periodontitis (basal cell carcinoma: p = 0.020, OR 0.987, 95% CI 0.976–0.998; endometrial cancer: p = 0.027, OR 0.984, 95% CI 0.970–0.998). However, periodontitis exerted no significant causal impact on the 19 other common cancers or the three subtypes of head and neck cancer. To conclude, our results support the theory that periodontitis contributes to an enhanced risk of head and neck cancer, particularly oropharyngeal cancer, with Fusobacterium nucleatum functioning as a potential intermediary.
The association between overactive bladder and systemic immunity-inflammation index: a cross-sectional study of NHANES 2005 to 2018
Authors: Wei Baian , Zhao Ying , Lin Pinli , Qiu Wenqiang , Wang Shusheng , Gu Chiming , Deng Lili , Deng Tewei , Li Siyi 
Published: May 2024

AbstractCurrent research indicate that inflammation is linked to the development of overactive bladder (OAB). The aim of this study was to examine the correlation between OAB and the systemic immunity-inflammation index (SII) in the USA. We analyzed data from 31,881 participants in the National Health and Nutrition Examination Survey 2005–2018. SII, calculated as platelet count × neutrophil count/lymphocyte count, was categorized into quartiles. OAB was defined by the presence of urge urinary incontinence and nocturia. Weighted logistic regression models were used to examine the independent relationship between SII and OAB, adjusting for demographic factors, kidney function, and diabetes status. The results showed that each tenfold increase in log-transformed SII was associated with an 18% higher odds of OAB (OR 1.18, 95% CI 1.08–1.28) in the fully adjusted model. Compared to the lowest SII quartile, the highest quartile had a 28% increased OAB risk (OR 1.28, 95% CI 1.12–1.47). The positive association between SII and OAB risk was consistently observed across subgroups stratified by age, sex, race, marital status, education, and poverty level. Our study reveals a positive correlation between SII levels and OAB, indicating that higher SII levels are associated with an increased likelihood of developing OAB.
Bone turnover prediction in patients with chronic kidney disease (CKD) undergoing hemodialysis using shortened dynamic 18F-NaF PET/CT Ki–Patlak
Authors: Sanoesan Viyada , Phannajit Jeerath , Kingpetch Kanaungnit , Sawatnatee Thunyaluk , Phromphao Benchamat , Susantitaphong Paweena , Sukprakun Chanan , Khamwan Kitiwat 
Published: May 2024

AbstractThis study investigated whether Ki–Patlak derived from a shortened scan time for dynamic 18F-NaF PET/CT in chronic kidney disease (CKD) patients undergoing hemodialysis can provide predictive accuracy comparable to that obtained from a longer scan. Twenty-seven patients on chronic hemodialysis, involving a total of 42 scans between December 2021 and August 2023 were recruited. Dynamic 18F-NaF PET/CT scans, lasting 60–90 min, were immediately acquired post-injection, covering the mid-twelfth thoracic vertebra to the pelvis region. Ki–Patlak analysis was performed on bone time–activity curves at 15, 30, 45, 60, and 90 min in the lumbar spine (L1–L4) and both anterior iliac crests. Spearman’s rank correlation (rs) and interclass correlation coefficient were used to assess the correlation and agreement of Ki–Patlak between shortened and standard scan times. Bone-specific alkaline phosphatase (BsAP) and tartrate-resistant acid phosphatase isoform 5b (TRAP5b) were tested for their correlation with individual Ki–Patlak. Strong correlations and good agreement were observed between Ki–Patlak values from shortened 30-min scans and longer 60–90-min scans in both lumbar spine (rs = 0.858, p < 0.001) and anterior iliac crest regions (rs = 0.850, p < 0.001). The correlation between BsAP and Ki–Patlak in the anterior iliac crests was weak and statistically insignificant. This finding suggests that a proposed shortened dynamic 18F-NaF PET/CT scan is effective in assessing bone metabolic flux in CKD patients undergoing hemodialysis, offering a non-invasive alternative approach for bone turnover prediction.
Recent Advances in Ligand-Controlled Regio- or Stereodivergent Transition-Metal-Catalyzed Hydroelementation (H[E]) (E = H, B, Si, Ge) of C–C Unsaturated Systems
Authors: Park Sehoon 
Published: May 2024

AbstractReductive functionalization of C–C unsaturated systems, including alkenes and alkynes, with a range of hydroelements (H[E]) is one of the most fundamental and highly practical methods for the synthesis of functionalized hydrocarbons. Since the resultant hydrocarbon products have strong applicability as synthetic intermediates, numerous homogeneous organo(metallic) catalysts have been intensively utilized to date for reductive functionalization reactions. In particular, well-defined transition-metal-based catalysts capable of controlling the regio- or stereoselectivity of a product by harnessing the addition of H[E] (E = H, B, Si, Ge) into Cα–Cβ unsaturated bonds have drawn special attention. In this review, we describe recent examples of transition-metal catalytic systems (M = Fe, Co, Rh, Pd, Ni) for regio- or stereodivergent hydroelementation reactions of (conjugated) alkenes, alkynes, and allenes to give a pair of isomeric products in high selectivities from the same starting compounds simply by variation of the ligand. Mechanistic aspects of the ligand-controlled selectivity divergence are discussed in detail on the basis of experimental observations and/or computational insights.1	Introduction2	Hydroelementation of Alkenes and Alkynes3	Hydroelementation of Conjugated Dienes and Diynes4	Hydroelementation of Allenes5	Summary and Outlook
Dravet Syndrome: An Electroclinical, Genetic, Treatment, and Outcome Study of 35 Patients in Argentina
Authors: Caraballo Roberto H. , Veneruzzo Gabriel , Loos Mariana , Reyes Gabriela , Juanes Matías , Martín Eugenia , Melgarejo Duarte Sergio , Touzón María Sol , Alonso Cristina 
Published: May 2024

AbstractWe analyzed the electroclinical features, molecular findings, treatment, disease course, and outcomes of patients with Dravet syndrome (DS) with positive genetic markers seen at a public hospital in Argentina. A retrospective study was conducted assessing the clinical records of 44 patients who met the diagnostic criteria for DS according to the 2022 classification of epilepsy of the International League Against Epilepsy seen at our center between March 2018 and June 2023. Of 44 patients, 35 (18 males and 17 females), in whom genetic studies yielded positive results, were included. Median age was 9 years (range 4 to 16 years), and the median time of follow-up was 10 years (range 3 to 14 years). The mean age at onset was 7 months. The first seizure was associated with febrile illness in all patients, and in 11 (31.4%), seizures were immediately preceded by either infectious disease or vaccination. Heterozygous pathogenic/likely pathogenic SCN1A variants were detected in 32 of the original 44 patients (73%), of which 47% were novel. Variants in other genes related to DS (HCN1, STXB1, and SCN1B) were identified in three patients. Cognitive delay and motor impairment were found to be more severe in patients that had multiple and drug-resistant seizures and in those who had the complete phenotype with myoclonic seizures. Novel SCN1A gene variants were identified in nearly half of the patients. The prognosis for cognitive development is unfavorable. Seizures are not well controlled with antiseizure medications and early treatment with ketogenic dietary therapy as well as cannabidiol should be considered.
Opportunities and Challenges for Malta’s Cruise Tourism and Its Growth Potential
Authors: Antonellini Luca 
Published: May 2024

Summary
This case study provides an analysis of cruise tourism in Malta for the period from 2002 to 2033, with a specific focus on the year 2023. Malta has experienced a significant growth in cruise tourism over the years, predominantly attributable to the expansion of its home-port function and to the growth in average ship capacity. The comprehensive examination of cruise traffic in 2023 was conducted by employing a range of assessments, including market-related evaluations, and passenger and ship segmentation. A projection of cruise traffic for the ensuing decade was developed. Additionally, a thorough examination was undertaken of the principal tourist attractions in Malta, with attention given to those that are negatively impacted by the problem of overtourism. Furthermore, potential resolutions are proposed with the additional objective of enhancing the destination’s environmental sustainability.

Information
© The Author 2024
Direct inversion of the Longitudinal ray transform for 2D residual elastic strain fields
Authors: Wensrich C M , Holman S , Courdurier M , Lionheart W R B , Polyakova A P , Svetov I E 
Published: May 2024

Abstract
We examine the problem of Bragg-edge elastic strain tomography from energy resolved neutron transmission imaging. A new approach is developed for two-dimensional plane-stress and plane-strain systems whereby elastic strain can be reconstructed from its Longitudinal ray transform (LRT) as two parts of a Helmholtz decomposition based on the concept of an Airy stress potential. The solenoidal component of this decomposition is reconstructed using an inversion formula based on a tensor filtered back projection (FBP) algorithm whereas the potential part can be recovered using either Hooke’s law or a finite element model of the elastic system. The technique is demonstrated for two-dimensional plane-stress systems in both simulation, and on real experimental data. We also demonstrate that application of the standard scalar FBP algorithm to the LRT in these systems recovers the trace of the solenoidal component of strain and we provide physical meaning for this quantity in the case of 2D plane-stress and plane-strain systems.