bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of the Extent of Surgical Resection on Survival and Quality of Life in Patients with Supratentorial Glioblastomas and Anaplastic Astrocytomas
Authors: Ammirati Mario , Vick Nicholas , Youlian Liao , Ivan Ciric , Mikhael Michael 
Published: May 2010

Abstract
Thirty-one patients operated upon for supratentorial glioblastomas or anaplastic astrocytomas were studied to evaluate the effect of the extent of surgical resection on the length and quality of survival. The median age was 50 years and the median preoperative Karnofsky rate was 80. Twenty-one patients (68%) had glioblastoma multiforme, and 10 patients (32%) had anaplastic astrocytoma. Early postoperative enhanced computed tomography was used to determine the extent of tumor resection. Gross total tumor resection was accomplished in 19 patients (61%), and subtotal resection was performed in 12 patients (39%). The two groups were comparable regarding age, sex, pathological condition, preoperative Karnofsky rating, tumor location, postoperative radiation therapy, and postoperative chemotherapy (P &gt; 0.05). The gross total resection group lived longer than the subtotal resection group by life table analysis (P &lt; 0.001; median survival of 90 and 43 weeks, respectively). Postoperatively, the mean functional ability measured by the Karnofsky rating was significantly increased in the gross total resection group (P = 0.006), but not in the subtotal resection group (P &gt; 0.05). The difference in degree of change between preoperative and postoperative Karnofsky rating in the two groups was statistically significant (P = 0.002). The gross total resection group spent significantly more time after the operation in an independent status (Karnofsky rating ≥ 80) compared to the subtotal resection group (P = 0.007; median time of 185 and 12.5 weeks, respectively). Gross total resection of supratentorial glioblastomas and anaplastic astrocytomas is feasible and is directly associated with longer and better survival when compared to subtotal resection.
Long Term Results of Transsphenoidal Adenomectomy in Patients with Cushing's Disease
Authors: Nakane Toshichi , Kuwayama Akio , Watanabe Masao , Takahashi Tatsuo , Kato Tetsuo , Ichihara Kaoru , Kageyama Naoki 
Published: May 2010

Abstract
As part of an ongoing series, 100 patients with Cushing's disease underwent transsphenoidal operations. Pituitary adenomas were confirmed in 93 patients, and initial remission was achieved in 86 (92%) of them. Hypercortisolemia was not corrected in 7 patients, and in 4 this was due to invasive adenomas. These patients were subjected to irradiation, medical treatment, or both after operation. Only 7 of the 100 patients had no pituitary adenoma found at operation, and they obtained no clinical remission even after partial or subtotal hypophysectomy. Follow-up review, with an emphasis on endocrinological studies, was performed on these patients for a mean period of 38 months. Seventy-eight patients were in long term remission after operation and had restoration of noncorticotropic hormone secretion as well as pituitary-adrenal function. Recurrence was noted in 8 patients after 19 to 82 months in remission. In all of these patients, pituitary adenomas were verified by reoperation and no case of corticotrophic cell hyperplasia was noted. We conclude that late recurrence of Cushing's disease may occur after adenoma removal and is due to the regrowth of adenoma cells left behind in the peritumoral tissue at the first operation. In view of the overall remission rate, transsphenoidal adenomectomy is considered a highly effective treatment for Cushing's disease.
Spinal Cord Decompression for Gaucher's Disease
Authors: Goldblatt Jack , Keet Peter , Dall Desmond 
Published: May 2010

Abstract
We report an individual with Type I nonneuronopathic Gaucher's disease who experienced the rare complication of spinal cord compression secondary to a sclerotic vertebral fracture. He successfully underwent anterolateral spinal cord decompression and spinal fusion despite the severity of his generalized skeletal disease.
Spinal Cord Proliferative Sparganosis in Taiwan: A Case Report
Authors: Lo Yuk-keung , Chao David , Yan Sui-hang , Liu Hsiu-chi , Chu Fu-li , Huang Chun-I , Chang Tsuen , Liu Hung-cheng 
Published: May 2010

Abstract
A 43-year-old woman suffered from low back pain and bilateral footdrop. A cisternal myelogram unexpected revealed multiple filling defects in the spinal canal extending from the lower cervical region to the caudal equina. Diagnostic exploration revealed numerous cystic organisms adhering to the spinal cord and nerve roots. Histopathological examination showed these organisms to be proliferative sparganum cestode larvae. Although these cestode larval infections have been reported a dozen times in humans from various parts of the world, this is probably the first reported case of spinal cord infection.
Multiple Sclerosis Plaque Simulating Cerebral Tumor: Case Report and Review of the Literature
Authors: Mastrostefano Roberto , Occhipinti Emanuele , Bigotti Giulio , Pompili Alfredo 
Published: May 2010

Abstract
Multiple sclerosis rarely may present as a focal cerebral mass with clinical features and computed tomographic scan appearances of cerebral tumor. Distinguishing between these can be difficult or impossible. We report a case of a multiple sclerosis plaque involving the parietal lobe with mass effect; clinical and radiological features had led to a diagnosis of cerebral tumor.
Demyelinating Disease of Corpus Callosum Presenting as Glioma on Magnetic Resonance Scan: A Case Documented with Pathological Findings
Authors: Kalyan-Raman Uma P. , Garwacki Dennis J. , Elwood Patrick W 
Published: May 2010

Abstract
Magnetic resonance imaging (MRI) has improved the diagnosis of several pathological entities of the brain. MRI especially has been credited with distinguishing demyelinating diseases of the central nervous system from other diseases. The presence of a mass effect in a demyelinating disorder, however, makes difficult the distinction between tumor and a demyelinating disease. We report a case of a demyelinating disorder simulating an infiltrating glioma of the corpus callosum on MRI scan, resulting in surgical intervention. To our knowledge, this is the first case to be reported with MRI and documented pathological findings.
Spinal Cord Stimulation for Amelioration of Spasticity: Experimental Results
Authors: Maiman Dennis J. , Myklebust Joel B. , Barolat-Romana Giancarlo 
Published: May 2010

Abstract
Fourteen cats underwent 500-g/cm dorsal impact injuries to the spinal cord and the placement of stimulating electrodes above and below the level of injury at T8. After recovery from the surgical procedure and the development of spasticity, each animal participated in several trials of spinal cord stimulation (SCS). Cord stimulation was provided above or below the level of injury using currents of less than 0.75 mA at 100 Hz. Electromyogram changes in hamstring and quadricep muscles (during spasms induced by dorsiflexion of the paw) were monitored. All animals showed complete paraplegia and, at 3 weeks, severe spasms. Spasticity was aggravated by SCS delivered above the level of injury. Spasms were markedly suppressed by monopolar stimulation delivered below the level of the lesion. Effects were maximal with the negative electrode applied to the cord and were slightly less with reversal of polarity. Muscle excitation was seen before diminution of spasms when bipolar currents were used. All effects lasted only as long as currents were delivered. These animal trials suggest that the effects of SCS are directly related to the current and its type. Beneficial effects were seen only when currents were delivered below the level of injury; this suggests that SCS activates local inhibitory processes or depolarizes local excitatory pathways. The poor results with bipolar stimulation do not support action on a multisynaptic cord system in short term stimulation.
Hydrosyringomyelia and Its Management in Childhood
Authors: Hoffman Harold J. , Neill John , Crone Kerry R. , Hendrick Bruce E. , Humphreys Robin P. 
Published: May 2010

Abstract
Syringomyelia, once regarded as a degenerative disease of adults, is now recognized to be a disorder usually associated with the Chiari malformation and occurring in patients of all ages. We have reviewed 47 patients with syringomyelia treated on the Neurosurgical Service at the Hospital for Sick Children during the years 1977 to 1985. Twelve of these patients had a Chiari I malformation, 30 had a Chiari II malformation, and 5 had an acquired Chiari malformation. Thirty-one of these patients were treated by decompression of the Chiari malformation and plugging of the obex, 5 were treated by a simple posterior fossa decompression, 9 were treated by shunting of the syringomyelic cavity, and 2 were treated by a combined decompression of the posterior fossa and shunting of the syrinx. The Gardner procedure (decompression of the Chiari malformation and plugging of the obex) was the procedure most commonly used in managing our group of patients and resulted in improvement in over 70% of patients.
Comparative Evaluation of Intracranial Epidermoid Tumors with Computed Tomography and Magnetic Resonance Imaging
Authors: Olson Jeffrey J. , Beck David W. , Crawford Stephen C. , Menezes Arnold H. 
Published: May 2010

Abstract
The diagnosis of intracranial epidermoid tumors with computed tomography (CT) is often difficult because of indistinct margins, close proximity to the skull base, and a density similar to that of cerebrospinal fluid (CSF). Recent experience with six histologically confirmed epidermoid tumors served to emphasize the value of magnetic resonance (MR) imaging in studying these lesions. MR images were obtained using varying spin echo and inversion recovery techniques with a 0.5-tesla superconducting magnet. CT with and without enhancement had been performed in each case. In Case 1, CT showed an ill-defined left cerebellopontine angle hypodensity. MR imaging clearly showed the presence of abnormal tissue at that location. Case 2 showed a CSF density mass in the right upper posterior fossa. MR imaging of that area showed a variegated signal of a mass extending supratentorially. CT of Case 3 showed a left medial middle fossa hypodensity with an enhancing rim. MR imaging showed a clearly extraaxial mass in that location. In Case 4, a diffuse cerebellar hemispheric hypodensity was observed on CT and was clearly demarcated by MR studies. A huge lesion, thought initially to be an arachnoid cyst on CT of Case 5, was seen on MR imaging to be a large, extraventricular mass displacing the temporal lobe. Finally, CT in Case 6 was suggestive of a poorly demarcated right cerebellopontine angle lesion, which was seen on MR images to be extraaxial, displacing the brain stem. Various MR images more clearly demonstrate the extent of abnormal tissue than CT of epidermoid tumors. Although it does not give a specific tissue diagnosis, MR is of great value in planning the optimal surgical approach to these lesions.
“Giant Pneumoaneurysm” after Combined Internal Carotid Artery Occlusion and Extracranial-Intracranial Anastomosis
Authors: Inagawa Tetsuji , Ogasawara Hidenori , Kamiya Kazuko , Taguchi Haruyoshi 
Published: May 2010

Abstract
A patient with a giant aneurysm of the internal carotid artery (ICA) was treated by combined ICA occlusion in the neck and superficial temporal artery to middle cerebral artery anastomosis. Six months after complete closure of the ICA, the patient had episodes of nasal discharge mixed with dark red, old blood. Computed tomographic scan demonstrated that the lumen of the giant aneurysm was filled with a large amount of air, which communicated with the nasal cavity. Not finding a similar case in the literature, we named this entity “giant pneumoaneurysm.” After direct operation, the giant pneumoaneurysm collapsed. This unusual complication may be due to a decrease of blood supply to the aneurysmal wall through the vasa vasorum.
Demonstration by Magnetic Resonance of Symptomatic Spinal Epidural Lipomatosis
Authors: Healy Mark E. , Hesselink John R. , Ostrup Richard C. , Alksne John F. 
Published: May 2010

Abstract
In patients with Cushing's syndrome or morbid obesity, excessive accumulation of fat in the hips, upper back, abdomen, and mediastinum is well known (1, 3, 7). Excessive deposition of fat in the epidural space is less common, but must be recognized as a potential cause of neurological deficit (1-8). We report a patient with iatrogenic Cushing's syndrome, in whom magnetic resonance imaging (MRI) established the specific diagnosis of spinal cord compression secondary to excess epidural fat.
Myelopathy Due to Diffuse Thickening of the Cervical Dura Mater in Maroteaux-Lamy Syndrome: Report of a Case
Authors: Tamaki Norihiko , Kojima Noriaki , Tanimoto Michinori , Suyama Touru , Matsumoto Satoshi 
Published: May 2010

Abstract
A rare case of diffuse thickening of the cervical dura mater leading to cord compression in Maroteaux-Lamy syndrome (mucopolysaccharidosis VI) is reported. Spinal computed tomographic scans after intrathecal metrizamide injection and magnetic resonance images are shown. This condition presents as cervical myelopathy. Early decompression can be beneficial for patients with this infrequent metabolic disorder.
Tumors of the Brachial Plexus
Authors: Lusk Michael D. , Kline David G. , Garcia Carlos A. 
Published: May 2010

Abstract
Over a 17-year period, 56 patients with 57 tumors involving the brachial plexus were operated upon. The 40 neural sheath tumors included 26 neurofibromas, 8 schwannomas, 4 malignant neural sheath tumors, 1 fibrosarcoma, and 1 meningioma. Nine of the neurofibromas were associated with von Recklinghausen's disease (VRD), and 2 others were what was termed regionalized neurofibromatosis characterized by involvement of one limb with extension along the course of one or more plexus elements. Seventeen tumors were not of neural sheath origin; 7 were benign and 10 were metastatic malignant tumors compressing or invading the plexus. Benign neurofibromas and malignant sheath tumors almost always presented with pain or functional neural deficit, whereas schwannomas often presented with a palpable mass as their only initial symptom. Patients with solitary neurofibromas were significantly older, often female, and more likely to have tumor on the right side than patients with schwannomas, malignant neural sheath tumors, or neurofibromas associated with VRD. Solitary neurofibromas could often be totally resected without added deficit by sacrificing fascicles entering and leaving tumor that were determined to be “nonfunctional” by intraoperative nerve action potential recordings. Resection of neurofibromas associated with VRD sometimes but not always resulted in significant loss. Operation is nonetheless recommended, especially when malignancy is suspected because of rapidly increasing size, when severe pain or neural deficit is present, or when compression of adjacent plexus elements is a concern. Schwannomas and benign non-neural sheath tumors can usually be extirpated without damage to plexus elements. Forequarter amputation is advised for malignant intrinsic tumors involving distal plexus elements even though gross total resection seems feasible.
Somatosensory Evoked Potential Monitoring of Temporary Middle Cerebral Artery Occlusion during Aneurysm Operation
Authors: Mooij Jan J. A. , Buchthal Anna , Belopavlovic Milan 
Published: May 2010

Abstract
Somatosensory evoked potentials (SEPs) in response to median nerve stimulation were used as a guide to cortical function during temporary occlusion of the distal M1 segment of the middle cerebral artery (MCA) in the surgical treatment of five large aneurysms of the MCA bifurcation. MCA occlusion times ranged from 8 to 19 minutes under moderate hypothermia at 28.8° to 30.3°C. SEPs were preserved for variable times during MCA occlusion, ranging from no increase in latency after 13 minutes of occlusion to severe deterioration after 6 minutes. In no case was MCA occlusion maintained for longer than 3 minutes in the presence of a severely disturbed SEP. Recovery of the SEP to its preoperative relationship with that of the nonoperated hemisphere was seen in all cases before the end of operation. All patients were awake after rewarming at the end of operation without any neurological deficit. Monitoring the SEP pertaining to the territory of a cerebral artery during its temporary occlusion can help avoid ischemic damage and will allow the surgeon to take advantage of the several benefits of this technique in aneurysm surgery. (Neurosurgery 21:492-496, 1987)
Sciatica and Epidural Gas
Authors: Beatty Robert A. 
Published: May 2010

Abstract
Epidural gas in the patient with sciatica can sometimes provide a clue that there is a surgically treatable lesion. Our patient had the sudden onset of sciatica at night, which was relieved by walking. An intraspinal synovial cyst was associated with epidural gas. (Neurosurgery 21:537-539, 1987)
Cerebellar Abscess: The Impact of Computed Tomographic Scanning
Authors: van Dellen James Rikus , Bullock Ross , Postma Martinus Hermannus 
Published: May 2010

Abstract
Thirty-four cases of cerebellar abscess, diagnosed by computed tomographic (CT) scanning, were managed according to a standard protocol during a 4-year period. Triple high dosage intravenous antibiotics were used, open catheter drainage of the abscess was instituted, and external ventricular drainage was added if obvious hydrocephalus was present. Seventeen patients made a good recovery, and five remained minimally disabled. Ten patients died, and two were left severely disabled. A relationship between the level of consciousness on admission and final outcome was established. In addition, two particular CT scan features (viz. the presence of hydrocephalus and the stage of the abscess) were significant adverse prognostic factors. (Neurosurgery 21:547-550, 1987)
Solitary Plasmacytoma of the Calvarium: Two Cases Treated by Operation Alone
Authors: Arienta Cesare , Caroli Manuela , Ceretti Laura , Villani Roberto 
Published: May 2010

Abstract
Two cases of solitary plasmacytoma of the calvarium operated on with radical removal are reported. The two patients were not submitted to postoperative radiotherapy, unlike other cases reported in the literature. The authors stress that soiltary plasmacytoma of the calvarium may have a good prognosis if radically removed, and in these cases radiotherapy is not necessary. (Neurosurgery 21:560-563, 1987)
Unilateral Normal Perfusion Pressure Breakthrough after Carotid Endarterectomy: Case Report
Authors: Andrews Brian T. , Levy Michael L. , Dillon William , Weinstein Philip R. 
Published: May 2010

Abstract
The authors report a case of unilateral malignant cerebral edema that occurred after the removal of a high grade atheromatous lesion of the ipsilateral internal carotid artery. A form of unilateral normal perfusion pressure breakthrough caused by postischemic impairment of cerebrovascular autoregulation and exacerbated by systemic hypertension is thought to have contributed to this complication. Control of the hypertension and treatment of the cerebral edema with mannitol and dexamethasone led to a complete neurological recovery. (Neurosurgery 21:568-571, 1987)
Anterior Inferior Cerebellar Artery Aneurysm, Carotid Bifurcation Aneurysm, and Dural Arteriovenous Malformation of the Tentorium in the Same Patient
Authors: Kaech Denis , de Tribolet Nicolas , Lasjaunias Pierre 
Published: May 2010

Abstract
An exceptional combination of intracranial vascular malformations is reported: distal anterior inferior cerebellar artery (AICA) aneurysm, carotid bifurcation aneurysm, and dural arteriovenous malformation (DAVM) of the tentorium. The AICA aneurysm was the source of recurrent subarachnoid and cerebellar hemorrhage, revealed only after repeated vertebral angiography. After external drainage of associated hydrocephalus, both aneurysms were successfully clipped and the dural malformation was subtotally embolized. The literature concerning AICA aneurysms, DAVMs, and combined intracranial vascular malformations is reviewed and discussed. (Neurosurgery 21:575-582, 1987)
Intracerebral Hemorrhage and Hematoma in Behçet's Disease: Case Report
Authors: Altinörs Nur , Şenveli Engin , Arda Nuri , Türker Ayhan , Kars Zafer , çinar Nusret , özkan Seyhan 
Published: May 2010

Abstract
The authors describe a patient with Behçet's disease who suffered from intracerebral hemorrhage 2½ years after the initial diagnosis. There is strong evidence that this situation is not merely a coincidence; rather, these two abnormalities have a cause and effect relationship. (Neurosurgery 21:582-583, 1987)
Intrasellar Tuberculoma: Case Report
Authors: Esposito Vincenzo , Fraioli Bernardo , Ferrante Luigi , Palma Lucio 
Published: May 2010

Abstract
We report a unique case of exclusively intrasellar tuberculoma. The patient was operated on by the transsphenoidal approach, which allowed total removal of the lesion and prevented cerebrospinal fluid contamination. After histological diagnosis, the patient was treated with isoniazid, 300 mg daily for 3 months, as prophylaxis against tuberculous meningitis. (Neurosurgery 21:721-723, 1987)
Subdural Empyema Occurring 20 Years after Trauma: Case Report
Authors: Tokoro Kazuhiko , Yamataki Akira , Nakajima Fumoto 
Published: May 2010

Abstract
The authors report a case of subdural empyema that occurred 20 years after a severe closed head injury and was treated surgically with good results. Traumatic subdural empyema of this late onset is rare. The literature is reviewed, and the mechanism of a delayed presentation is discussed. (Neurosurgery 21:724-726, 1987)
Neurinoma of the Trigeminal Root Presenting as Atypical Trigeminal Neuralgia: Diagnostic Values of Orbicularis Oculi Reflex and Magnetic Resonance Imaging
Authors: Tanaka Akira , Maruta Yoshirou , Maruta Yoshirou 
Published: May 2010

Abstract
A case of trigeminal root neurinoma presenting as atypical trigeminal neuralgia was reported. The orbicularis oculi reflex was absent on the affected side, but reappeared after operation. The demonstration of the tumor was much clearer on magnetic resonance imaging. The usefulness of these electrophysiological and radiological studies in differentiating varied entities of trigeminal neuralgia is stressed. (Neurosurgery 21:733-736, 1987)
Middle Fossa Facial Schwannoma Removed Via the Intracranial Extradural Approach: Case Report and Review of the Literature
Authors: Rosenblum Bruce , Davis Raphael , Camins Martin 
Published: May 2010

Abstract
A case of an intracranial facial schwannoma originating from the geniculate ganglion in a patient without neurofibromatosis is presented. Preoperative diagnosis and determination of site of origin along the facial nerve course is stressed through analysis of radiographic and clinical features. The tumor was completely removed using an intracranial, extradural approach. (Neurosurgery 21:739-741, 1987)