bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transfert et vécu du temps avec les patients Alzheimer
Authors: Payan Ségolène , Majid Safouane Abdel 
Published: January 2011

Soumis à des figures singulières de la condensation et du déplacement, le discours des patients Alzheimer dits déments, et leur rapport au temps traduisent les effets de l’âge, des pertes successives et des remaniements que connaît la sphère objectale, ainsi que celles de ses modalités structurelles de liaisons aux autres. Une concomitance dans l’éclipse du sujet s’observe avec la perte progressive des coordonnées de l’autre dans son économie psychique. Comment face aux modalités singulières de dénouement-dénouage, qu’impose « l’expérience du vieillir » jusque dans la chaîne signifiante et la structure du sujet, et à partir de la psychanalyse, écouter quelque chose qui ne se dit que sous forme de reste et de débris. Comment retrouver les traces de la subjectivité dans un discours qui ne semble plus faire récit, car marqué par la déliaison et la discontinuité ? Quelles en sont les implications et incidences dans le transfert et les options thérapeutiques ?
Le transfert en psychanalyse d'enfant
Authors: Fessaguet Dominique 
Published: January 2011

Le récit « Le Petit Prince » de Saint-Exupéry va servir de fresque métaphorique pour une aventure analytique singulière entre un adulte et un enfant. Il s’agit d’un enfant qui poursuit son chemin en étroite collaboration, voire tient son analyse d’une « main de maître ». Le conte offrira les facettes d’une relation transféro-contre-transférentielle sous les augures de la « chimère » terme emprunté à M de M’Uzan, pour sortir ensuite de cette relation aux objets partiels, et ouvrir les espaces nécessaires au « Petit Prince » pour métaboliser sa relation d’amour à la rose et repartir dans son monde.
Hypnose et fascination collective : métapsychologie des processus d'adhésion à la scientologie – l'envers du discours psychanalytique
Authors: Lamote Thierry , Mary Arthur 
Published: January 2011

Un rapprochement quelque peu abusif tend à assimiler l’audition, psychothérapie de la Scientologie inspirée de la méthode cathartique de J. Breuer, à une variante de la cure psychanalytique. Nous montrerons comment les processus psychiques en jeu dans la Scientologie s’organisent suivant une « discursivité » à situer à l’envers du discours analytique. Malgré la technique hypnotique sur laquelle elle s’appuie, les modalités spécifiques de l’« audition » empêchent que s’initie un transfert entre l’audité et l’auditeur. Ce dispositif thérapeutique d’évacuation du transfert mis au cœur de la Scientologie induit des effets d’adhésion à la théorie et au groupe sans pour autant qu’une figure de meneur soit nécessaire. La secte fondée par L. Ron Hubbard propose ainsi un régime métapsychologique original dans lequel la fascination collective pour un tenant lieu de l’Idéal du moi se renverse en une intériorisation surmoïque (et impersonnelle) des exigences de la Scientologie. Nous montrerons comment le traitement du transfert et l’éthique qui le sous-tend distinguent le mieux la cure freudienne de la cure hubbardienne.
Le rendez-vous de Königsberg
Authors: Assoun Paul-Laurent 
Published: January 2011

En partant de l’événement de la supervision, il s’agit de situer la temporalité spécifique du transfert, entre répétition et événement, continuum et discontinuité. Si le système inconscient est « hors-temps », c’est dans la cure qu’il se « ré-historicise ». Le « transfert en différé », reconstruit dans la « supervision » ou « contrôle », permet de le réexpérimenter. Entre les deux adages – « tout ce qui n’est pas déclinable » comme référable au transfert et « avec le temps tout deviendra clair » – se déploie ce temps d’avènement de l’objet pour le désir, par la fonction du tiers. Les pas en mènent à Königsberg, cette ville dont Freud, lors d’une supervision décisive de Lou Salomé, fait le lieu d’échéance spatio-temporel du transfert. Un certain symptôme somatique résiduel vient signer la dépendance transférentielle : savoir la reconnaître, c’est être à la hauteur du « rendez-vous de Königsberg », cette ville qui a donné lieu à une énigme logique qui trouve une résonance saisissante dans l’acte analytique.
Association of Insulin Resistance with Serum Interleukin-6 and TNF-α Levels during Normal Pregnancy
Authors: Jahromi Abdolreza Sotoodeh , Zareian Parvin , Madani Abdolhossein 
Published: January 2011

OverviewThe purpose of this study was to evaluate the role of Tumor Necrosis Factor-α (TNF-α) in insulin resistance (IR) during normal pregnancy.ApproachThis cross sectional study was carried out on 86 healthy pregnant women including 26, 23 and 37 individuals in the 1st, 2nd and 3rd trimesters, respectively, and in 21 healthy non pregnant women. Serum TNF-α concentration was measured by Enzyme Linked Immunosorbent Assay (ELISA) method.ResultsThere were significant differences between serum TNF-α and IL-6 levels in pregnant women as compared with maternal healthy controls. There was significant correlation between gestational age and Body Mass Index (BMI) (r = 0.28, P = 0.01). There was no significant correlation between gestational age and insulin resistance (IR). We also did not find correlations between IR and TNF-α and IR and IL-6 in pregnant women.ConclusionIn conclusion, our findings suggest that TNF-α and IL-6 are not greatly contributed to pregnancy induced insulin resistance in normal pregnancy.
Use of Prothrombin Complex Concentrate for Vitamin K Antagonist Reversal before Surgical Treatment of Intracranial Hemorrhage
Authors: Wong Yun 
Published: January 2011

Background Oral anticoagulant therapy (OAT) is used to prevent/treat thromboembolism. Major bleeding is common in patients on OAT; eg, warfarin increases intracranial hemorrhage (ICH) risk. Case A 71-year-old male on warfarin (to reduce stroke risk) presented at Accident and Emergency Minor Injuries Unit with headache after reportedly sounding ‘drunk’. On triage, the patient appeared lucid and well. However, International Normalized Ratio (INR) was 4.1. Head computed tomography (CT) indicated a large right-sided subdural hematoma. Prothrombin complex concentrate (PCC; Beriplex® P/N, CSL Behring) with vitamin K normalized the INR within minutes of administration. The patient underwent neurosurgery without complications, and was discharged after 5 days, with no residual neurological symptoms. Conclusions ICH patients can present with no neurological signs. In OAT patients with headache, INR must be established; if ≥ 3.0, normalization of INR and head CT are essential. PCC is the best option to rapidly reverse anticoagulation and correct INR pre-surgery.
Commentary on "Anisotropic finite-size scaling of an elastic string at the depinning threshold in a random-periodic medium"
Authors: Fedorenko Andrei 
Published: January 2011

A Commentary on the paper by S. Bustinagorry and A. B. Kolton [Pap. Phys. 2, 020008 (2010)].Received: 25 November 2010, Accepted: 6 January 2011; Edited by: A. Vindigni; DOI: 10.4279/PIP.020009
Late-onset Candida Keratitis after Descemet Stripping Automated Endothelial Keratoplasty: Clinical and Confocal Microscopic Report
Authors: Ortiz-Gomariz Amanda , Higueras-Esteban Alejandro , Gutiérrez-Ortega Ángel Ramón , González-Méijome José M. , Arance-Gil Angeles , Villa-Collar César 
Published: January 2011

Purpose TO report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). Methods We performed clinical and confocal scan on a patient who underwent DSAEK and phacoemulsification for Fuchs endothelial dystrophy and cataract. Results A 76-year-old woman who underwent uneventful DSAEK and phacoemulsification presented with white to cream deposits 3 months after DSAEK. Confocal microscopy showed a hyperintense deposit at the lenticule and interface. Confocal scan also disclosed intense haze and inflammation at the interface and clusters of hyperreflective round structures resembling epithelial cells within the interface area. No signs of hyphae-like structures were seen. Late-onset symptoms misled us into a bacterial chronic endophthalmitis diagnosis, and the patient was started on topical and systemic antibiotics. Despite intense antibiotic therapy, the patient developed severe endophthalmitis, so we performed anterior vitrectomy and the donor lenticule was removed. Microbiology results from the removed lenticule showed infection by C albicans. Antifungal therapy with systemic and topical voriconazole controlled the infection. Conclusions Candida interface keratitis is possible after DSAEK. The posterior location of infected tissue poses diagnostic and therapeutic challenges. In our case, the late onset of the symptoms and not performing corneoscleral rim cultures delayed correct diagnosis. This is the first reported case of post-DSAEK Candida keratitis with confocal microscopy images. A hyperintense granular deposit was seen at the lenticule and interface with confocal microscopy. We also observed intense haze, granular round structures resembling epithelial cells, and hyperreflective needle-shaped material at the interface. No hyphae-like structures were seen with confocal imaging.
Antihypertensive Medications and Eczematous Dermatitis in Older Adults
Authors: Ye Morgan , Chan Leslie N. , Douglas Ian , Margolis David J. , Langan Sinéad M. , Abuabara Katrina 
Published: May 2024

ImportanceRates of physician-diagnosed eczema have been increasing among older adults, but little is known regarding the pathophysiologic processes and best treatments in this subgroup. Preliminary data suggest that medications—antihypertensive medications in particular—may contribute to eczematous dermatitis; however, there are limited population-based data on the proportion of eczematous dermatitis diagnoses among older adults that may be attributed to antihypertensive drugs.ObjectivesTo determine whether antihypertensive drug use is associated with eczematous dermatitis in older adults.Design, Settings, and ParticipantsThis was a longitudinal cohort study of a population-based sample of individuals 60 years and older without a diagnosis of eczematous dermatitis at baseline. It was conducted at primary care practices participating in The Health Improvement Network in the United Kingdom from January 1, 1994, to January 1, 2015. Data analyses were performed from January 6, 2020, to February 6, 2024.ExposureExposure date by first prescription for an antihypertensive drug within each drug class.Main outcome measuresNewly active eczematous dermatitis was based on the first date for 1 of the 5 most common eczema codes used in a previously validated algorithm.ResultsAmong the total study sample of 1 561 358 older adults (mean [SD] age, 67 [9] years; 54% female), the overall prevalence of eczematous dermatitis was 6.7% during a median (IQR) follow-up duration of 6 (3-11) years. Eczematous dermatitis incidence was higher among participants receiving antihypertensive drugs than those who did not (12 vs 9 of 1000 person-years of follow-up). Adjusted Cox proportional hazard models found that participants who received any antihypertensive drugs had a 29% increased hazard rate of any eczematous dermatitis (hazard ratio [HR], 1.29; 95% CI, 1.26-1.31). When assessing each antihypertensive drug class individually, the largest effect size was observed for diuretic drugs (HR, 1.21; 95% CI, 1.19-1.24) and calcium channel blockers (HR, 1.16; 95% CI, 1.14-1.18), and the smallest effect sizes were for angiotensin-converting enzyme inhibitors (HR, 1.02; 95% CI, 1.00-1.04) and β-blockers (HR, 1.04; 95% CI, 1.02-1.06).Conclusions and RelevanceThis cohort study found that antihypertensive drugs were associated with a small increased rate of eczematous dermatitis, with effect sizes largest for calcium channel blockers and diuretic drugs, and smallest for angiotensin-converting enzyme inhibitors and β-blockers. Although additional research is needed to understand the mechanisms underlying the association, these data could be helpful to clinicians to guide management when a patient presents with eczematous dermatitis in older age.
Cognitive Euroscience in Croatia: Price estimations in the new and old currency in the face of inflation
Authors: Beg Mia Šetić , Domijan Dražen 
Published: May 2024

AbstractDo customers convert values to a familiar currency (rescaling hypothesis) or do they learn item‐price pairs (relearning hypothesis) when they estimate the prices of consumer goods and services in a currency they are unfamiliar with? We addressed this question by replicating the study conducted in Portugal and Austria in 2001 and 2002, around the time when these countries switched to the euro (Marques & Dehaene, Journal of Experimental Psychology: Applied, 2004, 10, 148–155). The study was made in Croatia where university students (N = 181) were asked to estimate the typical price of a set of 60 items from November 2022 to June 2023, around the time at which changeover to the euro took place. The results support the rescaling hypothesis by showing concurrent improvements in the precision of price estimates for frequently and rarely bought items. The reliance on rescaling is probably caused by a high inflation that accompanied a changeover to the euro in Croatia.
Molecular Design and Organic Photovoltaic Applications of Carboxylate‐Functionalized P‐type Polymers
Authors: Du Mengzhen , Li Xianda , Mu Chenyu , Zhou Bingjie , Cong Peiqing , Liu Hongxing , Tang Ailing , Liu Yingliang , Zhou Erjun 
Published: May 2024

AbstractThe significant progress of p‐type and n‐type active layer materials in the past several years has pushed the power conversion efficiency (PCE) of organic solar cells (OSCs) toward 19%. Due to the relatively low synthesis cost and simple synthesis method of carboxylate‐containing building blocks, including thiophene, thieno[3,2‐b]thiophene, thieno[3,4‐b]thiophene, furan, pyrazine, benzodithiophene, benzothiazole, quinoxaline, etc., are widely used to construct p‐type photovoltaic polymers. These resulting carboxylate‐bearing polymers present downward energy levels, high absorption coefficient, narrow bandgap, high hole mobility, and strong aggregation behavior, which have dabbled in the fabrication of mechanically stretchable, semitransparent, indoor, and tandem OSCs, etc., and produce excellent photovoltaic performance. The low‐cost carboxylate‐containing copolymers exhibit a satisfying PCE approaching 17%, and the random terpolymer systems achieve a high PCE over 19%. This review focuses on the progress of carboxylate‐containing photovoltaic polymers, summarizes the molecular characteristics, discusses their structure‐performance relationship, and offers a summary and outlook on the challenges for future molecular development.
Multifunctional Conductive Hydrogel Interface for Bioelectronic Recording and Stimulation
Authors: Tang Hao , Li Yuanfang , Liao Shufei , Liu Houfang , Qiao Yancong , Zhou Jianhua 
Published: May 2024

AbstractThe past few decades have witnessed the rapid advancement and broad applications of flexible bioelectronics, in wearable and implantable electronics, brain–computer interfaces, neural science and technology, clinical diagnosis, treatment, etc. It is noteworthy that soft and elastic conductive hydrogels, owing to their multiple similarities with biological tissues in terms of mechanics, electronics, water‐rich, and biological functions, have successfully bridged the gap between rigid electronics and soft biology. Multifunctional hydrogel bioelectronics, emerging as a new generation of promising material candidates, have authentically established highly compatible and reliable, high‐quality bioelectronic interfaces, particularly in bioelectronic recording and stimulation. This review summarizes the material basis and design principles involved in constructing hydrogel bioelectronic interfaces, and systematically discusses the fundamental mechanism and unique advantages in bioelectrical interfacing with the biological surface. Furthermore, an overview of the state‐of‐the‐art manufacturing strategies for hydrogel bioelectronic interfaces with enhanced biocompatibility and integration with the biological system is presented. This review finally exemplifies the unprecedented advancement and impetus toward bioelectronic recording and stimulation, especially in implantable and integrated hydrogel bioelectronic systems, and concludes with a perspective expectation for hydrogel bioelectronics in clinical and biomedical applications.
Advances in Flexible Magnetosensitive Materials and Devices for Wearable Electronics
Authors: Yang Huali , Li Shengbin , Wu Yuanzhao , Bao Xilai , Xiang Ziyin , Xie Yali , Pan Lili , Chen Jinxia , Liu Yiwei , Li Run‐Wei 
Published: May 2024

AbstractEmerging fields, such as wearable electronics, digital healthcare, the Internet of Things, and humanoid robots, highlight the need for flexible devices capable of recording signals on curved surfaces and soft objects. In particular, flexible magnetosensitive devices garner significant attention owing to their ability to combine the advantages of flexible electronics and magnetoelectronic devices, such as reshaping capability, conformability, contactless sensing, and navigation capability. Several key challenges must be addressed to develop well‐functional flexible magnetic devices. These include determining how to make magnetic materials flexible and even elastic, understanding how the physical properties of magnetic films change under external strain and stress, and designing and constructing flexible magnetosensitive devices. In recent years, significant progress is made in addressing these challenges. This study aims to provide a timely and comprehensive overview of the most recent developments in flexible magnetosensitive devices. This includes discussions on the fabrications and mechanical regulations of flexible magnetic materials, the principles and performances of flexible magnetic sensors, and their applications for wearable electronics. In addition, future development trends and challenges in this field are discussed.
Antiferroelectric Ceramics for Energy‐Efficient Capacitors by Theory‐Guided Discovery
Authors: Gaur Anand P. S. , Choudhary Renu , Liu Binzhi , Mudryk Yaroslav , Johnson Duane D. , Cui Jun , Tan Xiaoli 
Published: May 2024

AbstractAntiferroelectric ceramics, via the electric‐field‐induced antiferroelectric (AFE)–ferroelectric (FE) phase transitions, show great promise for high‐energy‐density capacitors. Yet, currently, only 70–80% energy release is found during a charge–discharge cycle. Here, for PbZrO3‐based oxides, geometric nonlinear theory of martensitic phase transitions is applied (first used to guide supercompatible shape‐memory alloys) to predict the reversibility of the AFE–FE transition by using density‐functional theory to assess AFE/FE interfacial lattice‐mismatch strain that assures ultralow electric hysteresis and extended fatigue lifetime. A good correlation of mismatch strain with electric hysteresis, hence, with energy efficiency of AFE capacitors is observed. Guided by theory, high‐throughput material search is conducted and AFE compositions with a near‐perfect charge–discharge energy efficiency (98.2%), i.e., near‐zero hysteresis are discovered. And the fatigue life of the capacitor reaches 79.5 million charge–discharge cycles, a factor of 80 enhancement over AFE ceramics with large electric hysteresis.
Metal Nanoparticle‐Catalyzed Alkyne Cyclization for the Synthesis of Heterocycles
Authors: Tang Xiao , Jiang Yukang , Song Liangliang , Van der Eycken Erik V. 
Published: May 2024

AbstractHeterocycles are important compounds existed in diverse advanced chemicals, functional materials, bioactive molecules and natural products. Different strategies through transition metal‐catalyzed alkyne cyclization have been developed to synthesize various heterocycles. The merger of alkyne cyclization and metal nanoparticle catalysis has emerged as an important approach to diverse heterocycles. By using different kinds of metal nanoparticle catalysts, such as gold, silver, copper and palladium nanoparticles, a number of heterocycles are prepared with high yield and selectivity in a green, sustainable and highly efficient manner. This review summarizes and discusses recent achievements in metal nanoparticle‐catalyzed alkyne cyclization for the synthesis of heterocycles.
Rare Earth Nanoprobes for Targeted Delineation of Triple Negative Breast Cancer and Enhancement of Radioimmunotherapy
Authors: Ming Zi‐He , Zhang Yong‐Qu , Song Liang , Chen Min , Lin Lin‐Ling , He Yue‐Yang , Liu Wan‐Ling , Zhu Yuan‐Yuan , Zhang Yun , Zhang Guo‐Jun 
Published: May 2024

AbstractRadiotherapy demonstrates a synergistic effect with immunotherapy by inducing a transformation of “immune cold” tumors into “immune hot” tumors in triple negative breast cancer (TNBC). Nevertheless, the effectiveness of immunotherapy is constrained by low expression of tumor‐exposed antigens, inadequate inflammation, and insufficient tumor infiltrating lymphocyte (TILs). To address this predicament, novel lutecium‐based rare earth nanoparticles (RENPs) are synthesized with the aim of amplifying radiation effect and tumor immune response. The nanoprobe is characterized by neodymium‐based down‐conversion fluorescence, demonstrating robust photostability, biocompatibility, and targetability. The conjugation of RENPs with a CXCR4 targeted drug enables precise delineation of breast tumors using a near‐infrared imaging system and improves radiation efficacy via lutetium‐based radio‐sensitizer in vivo. Furthermore, the study shows a notable enhancement of immune response through the induction of immunogenic cell death and recruitment of TILs, resulting in the inhibition of tumor progression both in vitro and in vivo models following the administration of nanoparticles. Hence, the novel multifunctional nanoprobes incorporating various lanthanide elements offer the potential for imaging‐guided tumor delineation, radio‐sensitization, and immune activation post‐radiation, thus presenting an efficient radio‐immunotherapeutic approach for TNBC.
Carbon Binder Domain Inhomogeneity in Silicon‐Monoxide/Graphite Composite Anode by 2D Multiphysics Modeling
Authors: Gao Xiang , Xu Jun 
Published: May 2024

AbstractThe Carbon‐binder domain (CBD) plays a pivotal role in the performance of lithium‐ion battery electrodes. The heterogeneous distribution of CBD across the electrode has garnered significant attention. However, a thorough understanding of how this CBD inhomogeneity affects anode performance remains a crucial pursuit, especially when considering the inherent material variations present in the SiO/Graphite (SiO/Gr) composite anode. In this study, an electro‐chemo‐mechanical model is established that provides a detailed geometric description of the particles. This model allows to quantitatively uncover the effects of CBD inhomogeneity on the fundamental behaviors of the SiO/Gr composite anode. The findings indicate that reducing the proportion of CBD in the upper domain (near the anode surface) compared to the lower domain (near the current collector) positively influences electrochemical performance, particularly in terms of capacity and Li plating. However, such an arrangement introduces potential risks of mechanical failures, and it is recommended to incorporate a higher proportion of CBD alongside the SiO particles. Finally, an anode design with a lower CBD proportion in the upper domain exhibits superior rate performance. This study represents a pioneering modeling exploration of CBD inhomogeneity, offering a promising multiphysics model with significant potential for informing advanced battery design considerations.