bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intermuscular coherence as an early biomarker for amyotrophic lateral sclerosis: The protocol for a prospective, multicenter study
Authors: Issa Naoum P. , Aydin Serdar , Polley Eric , Carberry Nathan , Garret Mark A. , Smith Sean , Habib Ali A. , Baumgartner Nicholas W. , Soliven Betty , Rezania Kourosh 
Published: May 2024

Objective
To describe the protocol of a prospective study to test the validity of intermuscular coherence (IMC) as a diagnostic tool and biomarker of upper motor neuron degeneration in amyotrophic lateral sclerosis (ALS).

Methods
This is a multicenter, prospective study. IMC of muscle pairs in the upper and lower limbs is gathered in ∼650 subjects across three groups using surface electrodes and conventional electromyography (EMG) machines. The following subjects will be tested: 1) neurotypical controls; 2) patients with symptomatology suggestive for early ALS but not meeting probable or definite ALS by Awaji Criteria; 3) patients with a known ALS mimic. The recruitment period is between 3/31/2021 and 12/31/2025. Written consent will be sought from the subject or the subject’s legally authorized representative during enrollment.

Results
The endpoints of this study include: 1) whether adding IMC to the Awaji ALS criteria improve its sensitivity in early ALS and can allow for diagnosis earlier; 2) constructing a database of IMC across different ages, genders, and ethnicities.

Significance
This study may validate a new inexpensive, painless, and widely available tool for the diagnosis of ALS.
Ultrasound-guided percutaneous biopsy for focal liver lesions: Adverse events and diagnostic yield in a single-centre analysis
Authors: Pöschel Theresa , Blank Valentin , Schlosser Tobias , Lingscheidt Thomas , Böhlig Albrecht , Wiegand Johannes , Karlas Thomas 
Published: May 2024

Purpose
Ultrasound-guided biopsy of focal liver lesions (FLL) is a well-established procedure with crucial impact on therapeutic decisions. The safety and accuracy depend on needle type, tumour location and comorbidities. Modern oncological concepts often require large tumour specimens which may increase the procedural risk.

Materials and methods
We retrospectively collected data from consecutively scheduled ultrasound-guided FLL biopsies performed in an interdisciplinary ultrasound unit at a university hospital from 2015–2020. We analysed complication rates, diagnostic accuracy, and patient outcome in a one-year period.

Results
Of 426 scheduled interventions, 339 were included: 322 primary biopsies (40% female, median age 65 years, median BMI 25.4 kg/m2) and 17 rebiopsies in cases with undetermined diagnosis. Indications comprised 309 (96%) cases with suspected malignant lesions. Important comorbidities were type 2 diabetes (n = 107, 33%) and cirrhosis (n = 64, 20%). A conclusive histopathological diagnosis was achieved in 270 (84%) cases with a weak association with lesion size (OR 1.12 per cm, 95%CI 0.99–1.27). Greater BMI (OR 0.60 per 10 BMI points, 95%CI 0.34–1.05) showed a trend towards an insufficient diagnosis. Relevant complications occurred in 8 (2.5%) cases (2 major; 1 life-threatening). Multiple passes showed a trend towards adverse events (OR 2.32 for > 1 pass, 95%CI 0.99–5.42). 93 (29%) patients died during a median follow-up of 171 days.

Conclusion
Ultrasound-guided FLL biopsy is an efficient and safe diagnostic measure. The limitations of the procedure and its associated risks should be considered in patients with advanced malignancies.
Combining sentiment analysis and text mining with content analysis of farm vet interviews on mental wellbeing in livestock practice
Authors: Duncan Andrew J. , Henry Madeleine K. , Lamont Kate 
Published: May 2024

Background
The aim of the How Farm Vets Cope project was to co-design, with farm veterinary surgeons, a set of web-based resources to help them and others deal with the different situations that they can face. As part of the wider project, participants were recruited for one-to-one semi-structured phone interviews. These interviews focused on elements of job satisfaction and how the participants coped during periods of poor mental wellbeing or with setbacks and failure.

Methods
Transcripts of these interviews were analysed using both quantitative methods of sentiment analysis and text mining, including term frequency/inverse document frequency and rapid automated keyword extraction, and qualitative content analysis. The twin aims of the analysis were identifying the important themes discussed by the participants and comparing the results of the two methods to see what differences, if any, arose.

Results
Analysis using the afinn and nrc sentiment lexicons identified emotional themes of anticipation and trust. Rapid automated keyword extraction highlighted issues around age of vets and support, whilst using term frequency/inverse document frequency allowed for individual themes, such as religion, not present across all responses, to be identified. Content analysis supported these findings, pinpointing examples of trust around relationships with farmers and more experienced vets, along with some examples of the difference good support networks can make, particularly to younger vets.

Findings
This work has confirmed previous results in identifying the themes of trust, communication and support to be integral to the experience of practicing farm veterinary surgeons. Younger or less experienced vets recognised themselves as benefiting from further support and signposting, leading to a discussion around the preparation of veterinary students for entry into a farm animal vet practice. The two different approaches taken showed very good agreement in their results. The quantitative approaches can be scaled to allow a larger number of interviews to be utilised in studies whilst still allowing the important qualitative results to be identified
O IMPACTO DAS TEMPERATURAS EXTREMAS NA MORTALIDADE POR INFARTO NO MIOCÁRDIO NO MUNICIPIO DE SÃO PAULO.
Authors: Ikefuti Priscilla Venâncio 
Published: May 2024

O Infarto Agudo no Miocardio (IAM) é uma doença cardiovascular que acomete o coração altamente letal, sendo a maior causa de mortalidade no Brasil e no mundo. O IAM é uma doença crónica multicausal, onde hábitos não saudaveis do individuo está relacionado a elevada incidencia dos casos. Outros fatores que contribuem para o aumento dos casos de IAM são os de cunho ambiental como a temperatura e a poluição. Analisar a associação entre a mortalidade do Infarto no Miocardio (IAM) com valores extremos de temperatura, a partir do uso de modelos lineares generalizados (GLM). Foram utilizados dados de mortalidade por IAM coletados através do Programa Municipal de Informação sobre Mortalidade (PRO-AIM) que monitora diariamente registros de mortalidade de diversos casos no município de São Paulo. Foram utilizados os dados diários de mortalidade do capitulo IX – Doenças do Aparelho Circulatório classificados pelo Código Internacional de Doenças (CID-10) e dentro desse capitulo selecionamos o conjunto (I-20 a I-25) que corresponde as doenças ligadas ao (IAM) no período de 1999 a 2014. Os dados meteorológicos foram adquiridos na estação meteorológica do Instituto de Astronomia e Geofísica (IAG) da Universidade de São Paulo (USP). Para analisar a associação da mortalidade com as temperaturas foi utilizado um modelo linear generalizado empregando-se o método de quasi-Poisson e os modelos de lags distribuídos. Como resultado encontramos risco relativo alto (RR=1,20; IC: 1,04 – 1,49) para o frio, onde o risco aumentado esteve presente nos 21 dias de defasagem apos exposição, já para o calor, o risco foi registrado para temperaturas acima de 33ºC para os primeiros días de exposição a temperatura. Tendo em vista que o atendimento de urgência para os casos de IAM pode evitar óbitos, a melhor compreensão da importância do clima pode permitir o desenvolvimento de sistemas de alertas junto aos serviços de atendimento de urgência e o direcionamento de campanhas para a prevenção dos fatores de risco evitáveis.
Exploring the impact of vitamin D on tendon health: a comprehensive review
Authors: Tarantino Domiziano , Mottola Rosita , Sirico Felice , Corrado Bruno , Ruosi Carlo , Saggini Raoul , Pellegrino Raffaello 
Published: May 2024

Abstract
Tendons are vital components of the musculoskeletal system, facilitating movement and supporting mechanical loads. Emerging evidence suggests that vitamin D, beyond its well-established role in bone health, exerts significant effects on tendon physiology. The aim of this manuscript is to review the impact of vitamin D on tendons, focusing on its mechanisms of action, clinical implications, and therapeutic applications. A comprehensive search of scientific electronic databases was conducted to identify articles on the effects of vitamin D on tendon health. Fourteen studies were included in this review. Five studies were performed in vitro, and nine studies were conducted in vivo. Despite some conflicting results, the included studies showed that vitamin D regulates collagen synthesis, inflammation, and mineralization within tendons through its interaction with vitamin D receptors. Epidemiological studies link vitamin D deficiency with tendon disorders, including tendinopathy and impaired healing. Supplementation with vitamin D shows promise in improving tendon strength and function, particularly in at-risk populations such as athletes and the elderly. Future research should address optimal supplementation strategies and explore the interplay between vitamin D and other factors influencing tendon health. Integrating vitamin D optimization into clinical practice could enhance tendon integrity and reduce the burden of tendon-related pathologies.
Counterfactual language, emotion, and perspective: a sentence completion study during the COVID-19 pandemic
Authors: Rotter Stephanie , Liu Mingya 
Published: May 2024

Abstract
In 2020, the COVID-19 pandemic turned into a global crisis. Focusing on the deterioration in people’s mental health, we conducted two experiments, one in Germany and one in the UK, in January and February 2021, when both countries were in lockdown. Using a COVID-19-themed sentence completion task, we tested the direction of counterfactual thoughts in relation to egocentric (self-focused) versus non-egocentric (other-focused) perspective-taking. Results show that in both samples, more upward counterfactuals (mental simulation of better counterfactual worlds, relating to negative emotions) than downward counterfactuals (mental simulation of worse counterfactual worlds, relating to positive emotions) were produced in the egocentric condition. An opposite pattern was found in the non-egocentric condition. We conclude that emotions as expressed in counterfactual language are perspective-dependent.
Control of Remote Workers by Means of Artificial Intelligence
Authors: Sierocka Iwona 
Published: May 2024

Abstract
Remote work, by its very nature, is characterised by the performance of the duties of the employment relationship, in whole or in part, at a place chosen by the employee, at a time agreed upon with the employer. Despite the fact that the employee performs his/her work outside the employer’s place of business, he/she remains under the employer’s control. The issues under consideration here are the scope of this control and the manner in which it is carried out. In my deliberations, I focus on control performed with the use of algorithmic technologies, in particular artificial intelligence, for which a Regulation of the European Parliament and of the Council Laying Down Harmonised Provisions on Artificial Intelligence (Artificial Intelligence Act) was adopted on 23 June 2023.
The Impact of the DAC7 Directive on the Functioning of Platforms and Platform Operators, from the Perspective of the Legal Model of Their Collaboration with Individuals
Authors: Nyka Maciej , Zapolska Karolina 
Published: May 2024

Abstract
In order to achieve the main objective of sealing the tax system, Council Directive (EU) 2021/514 of 22 March 2021 Amending Directive 2011/16/EU on Administrative Cooperation in the Field of Taxation (DAC7) introduces an obligation to report income obtained by sellers via a digital platform in one of the Member States. However, the implementation of the provisions of DAC7 in the field of reporting also has non-fiscal consequences. The DAC7 Directive interferes in the way sales platforms function, imposing additional obligations on them which are closer to models of cooperation in employer–employee relations than in B2B relations.
An Institutional Perspective on the Number of Stent Retriever Pass and Rate of Recanalization in Mechanical Thrombectomy for Acute Ischemic Stroke: When to Stop?
Authors: Bheru Dan Charan  , Gaikwad Shailesh B , Jain Savyasachi , Garg Ajay , Devarajan Sebastian Leve Joseph , Srivastava MV Padma , Bhatia Rohit , Pandit Awadh Kishore , Kale Shashank Sarad 
Published: May 2024

Background and purpose: Mechanical thrombectomy is the standard treatment modality for flow restoration in acute ischemic stroke. In cases of persistent occlusion, the optimal number of retrieval attempts before considering procedure termination is currently undetermined and is a topic for research. Therefore in this study, we studied the impact of the number of stent retrieval maneuvers on the recanalization of vessels.Methods: In this retrospective single-center observational study we included 52 patients with large vessel occlusion who underwent stent retriever mechanical thrombectomy. Successful recanalization rate was defined as modified TICI (Thrombolysis in Cerebral Infarction) 2b or 3.Result: The overall successful recanalization rate was 44.24%. The recanalization rate per stent retrieval attempt was the highest in 1st attempt (28.84%) and no recanalization was observed with the 3rd, 5th, and 6th attempts (p<0.001). At most 6 retrieval attempts were used.Conclusions: After two retrieval attempts, 91% of the patients were successfully recanalized and other after the 5th attempt could not result in recanalization.
Mechanical Thrombectomy in Medium Vessels Occlusion (MeVOs): An Institutional Experience with M2 Divisions of Middle Cerebral Artery
Authors: Bheru Dan Charan  , Gaikwad Shailesh B , Jain Savyasachi , Garg Ajay , Devarajan Sebastian Leve Joseph , Srivastava M V Padma , Bhatia Rohit , Pandit Awadh Kishore , Kale Shashank Sarad 
Published: May 2024

Background: Mechanical thrombectomy has been established as a safe, standard and effective treatment option for occlusions of the proximal segment of the middle cerebral artery (MCA), as demonstrated in numerous studies. However, performing thrombectomy in the M2 divisions of MCA presents inherent challenges. In this institutional experience, we aim to delineate the recanalisation rates achieved through mechanical thrombectomy in cases involving the M2 segment of the MCA.Methods: We conducted a retrospective analysis of patients who underwent thrombectomy due to M2 MCA occlusions in the period from January 2018 to December 2021. Various factors affecting recanalisation rates were assessed.Results: A total of 15 patients with M2 segment occlusions of the middle cerebral artery were included in the study, comprising 11 in the superior division and 4 in the inferior division. The successful recanalisation rate was 72.33%, with notably higher success observed in cases of inferior division occlusion. The primary outcome of our study was the mTICI recanalisation status, categorised as successful recanalisation (mTICI = 2b or mTICI = 3) and unsuccessful recanalisation (mTICI = 1 or mTICI = 2a) and mRS at 6 months. None of the predictors assessed reached statistical significance.Conclusions: Mechanical thrombectomy demonstrates favourable efficacy and recanalisation rates in cases of M2 MCA division occlusion. Notably, inferior division occlusions exhibit a higher likelihood of successful recanalisation.
Double Parathyroid Adenoma Presenting as One Mass: A Case Report
Authors: Petruokaitė Rugilė , Eismontas Vitalijus , Samalavičius Narimantas Evaldas 
Published: May 2024

Background and Objectives: Primary hyperparathyroidism is a common endocrinological condition, which is usually caused by solitary parathyroid adenoma. The aim of this article is to present a case of double adenoma presenting as one and literature review on this topic.Case presentation: 56 years old female suffering from generalized fatigue, bone pain, unstable body weight and palpitations was diagnosed with primary hyperparathyroidism. Further investigation revealed elevated parathyroid hormone (PTH), ionized and total calcium levels. Imaging showed two adenomas merging into one. Parathyroidectomy was performed and final intraoperative PTH (IOPTH) decreased by 71.6%. Parathyroid adenoma measuring 40 mm x 15 mm x 11 mm and weighing 1 g 483 mg was excised. 7 weeks after surgery patient was feeling well but her PTH level was elevated again.Conclusions: As far as we know, the double parathyroid adenoma presented in this case report is the largest reported in the Northern Europe and the first one that presents as one mass within the region. Double adenoma increases the risk of recurrent primary hyperparathyroidism (PHPT) and requires more careful and longer follow up after surgery than solitary adenomas. Final IOPTH must decrease by at least 50% within 10 minutes. This case shows that despite final IOPTH drop by more than 50%, after few weeks normocalcemic elevated parathyroid hormone (NCePTH) phenomenon was noticed. This phenomenon does not indicate surgical failure.
Shaping Civil Liability in the Digital Age: AILD and the Revisited PLD
Authors: Rimkutė Deimantė 
Published: May 2024

This article assesses two proposals for directives put forward by the European Commission: The Artificial Intelligence Liability Directive and the revised Product Liability Directive. The first part of the article introduces and compares the two proposals for directives. The subsequent part assesses the key elements of the Directives, including the scope of the application; the proposed changes to procedural law (disclosure of evidence, presumptions); and the rules of the revised Product Liability Directive on the identification of product defects. The article concludes with suggested improvements to the proposals for both Directives.
Description of a new species of the cleptoparasitic bee genus Tetralonioidella Strand, 1914 (Hymenoptera: Apidae: Melectini) from India
Authors: Dohling Pynhunlin Nola Kharkrang , Dey Debjani 
Published: May 2024

AbstractA new species of the cleptoparasitic bee genus Tetralonioidella Strand, 1914, collected from Meghalaya, India is described. Only two species occur in India, namely Tetralonioidella himalayana (Bingham, 1897) and Tetralonioidella tricolor (Lieftinck, 1972). The new species, Tetralonioidella meghalayensis Dohling & Dey sp. n., is the third species of Tetralonioidella Strand, 1914 discovered in India. An updated checklist of species along with identification keys to female species of the genus Tetralonioidella from India are given. Illustrations of the female specimens studied are also provided.
Zabójstwo Prezydenta Polski Gabriela Narutowicza w 1922 roku. Refleksje z perspektywy stulecia
Authors: Pleskot Patryk 
Published: May 2024

Z geopolitycznego punktu widzenia rok 1922 może być postrzegany jako pierwszy „zwykły” rok w historii odrodzonej Rzeczpospolitej. Walki zbrojne zostały zakończone, granice ustalone i obronione. Niemniej z trudem osiągnięte, stosunkowe bezpieczeństwo zewnętrzne wywołało prawdziwą erupcję problemów wewnętrznych. Po pozbyciu się wspólnego wroga (przede wszystkim Sowietów) obudziły się demony, uśpione we wcześniejszych dziesięcioleciach z powodu nieistnienia państwowości polskiej. Duszny klimat osiągnął punkt szczytowy w ostatnim kwartale 1922 r., wraz z wyborami parlamentarnymi i prezydenckimi. Wyniki wyborów rozczarowały zarówno prawicę, jak i lewicę, okazały się za to stosunkowo korzystne dla mniejszości etnicznych. Napięta atmosfera, zaogniana przez agresywne media, owocowała walkami ulicznymi oraz wzrostem nastrojów antysemickich i nacjonalistycznych. Doprowadziło to do zbrodni: 16 grudnia Eligiusz Niewiadomski – fanatyczny, sfrustrowany nacjonalista – zamordował pierwszego w historii prezydenta Polski: Gabriela Narutowicza, zwolennika tolerancji i liberalizmu, wybranego raptem kilka dni wcześniej. Taki był tragiczny rezultat przemocy politycznej – zjawiska, które manifestuje się również współcześnie.
Roman Dmowski o Ukrainie – profetyczna projekcja realizmu politycznego
Authors: Borkowski Kamil 
Published: May 2024

Celem artykułu jest omówienie najważniejszych założeń wątku ukraińskiego w refleksji geopolitycznej Romana Dmowskiego. Autor zamierza wykazać, że rozważania Dmowskiego cechuje wyjątkowa trafność spostrzeżeń dotyczących zagadnień narodu i państwa ukraińskiego w kontekście ich wpływu na pozycję Rosji, Polski i Niemiec, a tym samym na europejskie i światowe środowisko bezpieczeństwa. Podejmując próbę analizy powyższego przedmiotu badań podkreślenia wymaga fakt, iż od jego publikacji minęło ponad 90 lat, a mimo to nie stracił on na aktualności, dowodząc tym samym słuszności postawionych tez. Uwzględniając bieżące, dramatyczne wydarzenia za naszą wschodnią granicą oraz skalę potencjalnego ryzyka jakie generują nie tylko w wymiarze regionalnym, ale również globalnym wydaje się uzasadnionym sięgnięcie do Kwestii ukraińskiej jako cennego źródła wiedzy na temat przyczyn obecnego konfliktu oraz jego możliwych konsekwencji.
PROSPECTIVE TEACHERS' PERSPECTIVES ON PEDAGOGICAL CHALLENGES EXPERIENCED DURING WORK-BASED LEARNING
Authors: Margeviča-Grinberga Ieva , Šūmane Ilze 
Published: May 2024

This study investigates prospective teachers' perspectives regarding pedagogical issues and evaluates their readiness to address these challenges during instructional practice. The research investigates the experiences and perspectives of 67 students currently enrolled in teacher education programmes by employing a narrative content analysis methodology. The results point to several significant areas of concern among prospective teachers. Initially, classroom management emerged as a primary challenge, with many students expressing anxiety about efficiently managing diverse classroom dynamics and maintaining discipline. This problem indicates the need to pay more attention to classroom management strategies in study courses. Furthermore, the findings emphasize difficulties in effectively differentiating instruction to meet the diverse needs of learners. It was indicated that there is a need for more concentrated training in inclusive teaching methods since students voiced worries about their capacity to adjust teaching approaches to accommodate a variety of learning styles and abilities. The study suggests that prospective teachers are generally enthusiastic about their future careers but also recognize significant pedagogical challenges. To properly prepare future educators for the realities of the classroom, these findings have implications for teacher education programmes. They indicate a need for a more specific focus on practical skills such as classroom management and inclusive teaching practices.