bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eliminating the Adverse Impact of Composition Modulation in Perovskite Light‐Emitting Diodes toward Ultra‐High Brightness and Stability
Authors: Li Zhiqi , Ren Zhiwei , Liang Qiong , Fong Patrick W. K. , Tian Jianjun , Li Gang 
Published: April 2024

AbstractExcess ammonium halides as composition additives are widely employed in perovskite light‐emitting diodes (PeLEDs), aiming to achieve high performance by controlling crystallinity and passivating defects. However, an in‐depth understanding of whether excess organoammonium components affect the film physical/electrical properties and the resultant device instability is still lacking. Here, the trade‐off between the performance and stability in high‐efficiency formamidinium lead iodide (FAPbI3)‐based PeLEDs with excess ammonium halides is pointed, and the underlying mechanism is explored. Systematic experimental and theoretical studies reveal that excess halide salt‐induced ion‐doping largely alters the PeLEDs properties (e.g., carrier injection, field‐dependent ion‐drifting, defect physics, and phase stability). A surface clean assisted cross‐linking strategy is demonstrated to eliminate the adverse impact of composition modulation and boost the operational stability without sacrificing the efficiency, achieving a high efficiency of 23.6%, a high radiance of 964 W sr−1 m−2 (The highest value for FAPbI3 based PeLEDs), and a prolong lifetime of 106.1 h at large direct current density (100 mA cm−2), concurrently. The findings uncovered an important link between excess halide salts and the device performance, providing a guideline for rational design of stable, bright, and high efficiency PeLEDs.
Ultra‐Highly Stiff and Tough Shape Memory Polyurea with Unprecedented Energy Density by Precise Slight Cross‐Linking
Authors: Chen Jiaoyang , Wang Zhifeng , Yao Bowen , Geng Yuhao , Wang Cheng , Xu Jianhua , Chen Tao , Jing Jiajie , Fu Jiajun 
Published: April 2024

AbstractShape memory polymers (SMPs) have attracted significant attention and hold vast potential for diverse applications. Nevertheless, conventional SMPs suffer from notable shortcomings in terms of mechanical properties, environmental stability, and energy density, significantly constraining their practical utility. Here, inspired by the structure of muscle fibers, an innovative approach that involves the precise incorporation of subtle, permanent cross‐linking within a hierarchical hydrogen bonding supramolecular network is reported. This novel strategy has culminated in the development of covalent and supramolecular shape memory polyurea, which exhibits exceptional mechanical properties, including high stiffness (1347 MPa), strength (82.4 MPa), and toughness (312.7 MJ m−3), ensuring its suitability for a wide range of applications. Furthermore, it boasts remarkable recyclability and repairability, along with excellent resistance to moisture, heat, and solvents. Moreover, the polymer demonstrates outstanding shape memory effects characterized by a high energy density (24.5 MJ m−3), facilitated by the formation of strain‐induced oriented nanostructures that can store substantial amounts of entropic energy. Simultaneously, it maintains a remarkable 96% shape fixity and 99% shape recovery. This delicate interplay of covalent and supramolecular bonds opens up a promising pathway to the creation of high‐performance SMPs, expanding their applicability across various domains.
Bioelectrochemical Sensing Using Benchtop Fabricated Nanoroughened Microstructured Electrodes
Authors: González‐Martínez Eduardo , González‐Martínez David A. , Moran‐Mirabal Jose M. 
Published: April 2024

AbstractCost‐effective miniaturized electrodes that maintain a high electroactive surface area (ESA) are needed for the widespread deployment of point‐of‐care sensors. Cost‐effective methods are recently developed to fabricate nanoroughened microstructured gold electrodes (NR‐MSEs) with ultrahigh ESA. In this work, the effectiveness of NR‐MSEs for bioelectrochemical enzymatic sensors is evaluated. A glucose sensor is constructed by first casting onto NR‐MSEs a solution containing reduced graphene oxide decorated with gold nanoparticles, glucose oxidase, and glutaraldehyde, followed by a solution containing ferrocene, and a layer of chitosan to prevent the leakage of sensor components. A urea biosensor is also fabricated using Nafion as a cationic exchanger for the electropolymerization of polyaniline, followed by the deposition of a composite containing urease, bovine serum albumin, and glutaraldehyde. The limit of quantification for both biosensors is below clinically relevant concentrations of the analytes in biofluids, 0.67 mm for glucose and 1.70 mm for urea. The sensors exhibit excellent performance in complex matrixes (human blood serum and wine for glucose and human blood serum and urine for urea), with recovery for spiked analytes in the range of 92–108%. It is anticipated that NR‐MSEs will expedite the development of highly sensitive bioelectrochemical sensors for use in resource‐limited settings.
Statistical Genomics Analysis of Simple Sequence Repeats from the Paphiopedilum Malipoense Transcriptome Reveals Control Knob Motifs Modulating Gene Expression
Authors: Liang Yingyi , Hao Jing , Wang Jieyu , Zhang Guoqiang , Su Yingjuan , Liu Zhong‐Jian , Wang Ting 
Published: April 2024

AbstractSimple sequence repeats (SSRs) are found in nonrandom distributions in genomes and are thought to impact gene expression. The distribution patterns of 48 295 SSRs of Paphiopedilum malipoense are mined and characterized based on the first full‐length transcriptome and comprehensive transcriptome dataset from 12 organs. Statistical genomics analyses are used to investigate how SSRs in transcripts affect gene expression. The results demonstrate the correlations between SSR distributions, characteristics, and expression level. Nine expression‐modulating motifs (expMotifs) are identified and a model is proposed to explain the effect of their key features, potency, and gene function on an intra‐transcribed region scale. The expMotif‐transcribed region combination is the most predominant contributor to the expression‐modulating effect of SSRs, and some intra‐transcribed regions are critical for this effect. Genes containing the same type of expMotif‐SSR elements in the same transcribed region are likely linked in function, regulation, or evolution aspects. This study offers novel evidence to understand how SSRs regulate gene expression and provides potential regulatory elements for plant genetic engineering.
HOXA‐AS2 Epigenetically Inhibits HBV Transcription by Recruiting the MTA1‐HDAC1/2 Deacetylase Complex to cccDNA Minichromosome
Authors: Qin YiPing , Ren JiHua , Yu HaiBo , He Xin , Cheng ShengTao , Chen WeiXian , Yang Zhen , Sun FengMing , Wang ChunDuo , Yuan SiYu , Chen Peng , Wu DaiQing , Ren Fang , Huang AiLong , Chen Juan 
Published: April 2024

AbstractPersistent transcription of HBV covalently closed circular DNA (cccDNA) is critical for chronic HBV infection. Silencing cccDNA transcription through epigenetic mechanisms offers an effective strategy to control HBV. Long non‐coding RNAs (lncRNAs), as important epigenetic regulators, have an unclear role in cccDNA transcription regulation. In this study, lncRNA sequencing (lncRNA seq) is conducted on five pairs of HBV‐positive and HBV‐negative liver tissue. Through analysis, HOXA‐AS2 (HOXA cluster antisense RNA 2) is identified as a significantly upregulated lncRNA in HBV‐infected livers. Further experiments demonstrate that HBV DNA polymerase (DNA pol) induces HOXA‐AS2 after establishing persistent high‐level HBV replication. Functional studies reveal that HOXA‐AS2 physically binds to cccDNA and significantly inhibits its transcription. Mechanistically, HOXA‐AS2 recruits the MTA1‐HDAC1/2 deacetylase complex to cccDNA minichromosome by physically interacting with metastasis associated 1 (MTA1) subunit, resulting in reduced acetylation of histone H3 at lysine 9 (H3K9ac) and lysine 27 (H3K27ac) associated with cccDNA and subsequently suppressing cccDNA transcription. Altogether, the study reveals a mechanism to self‐limit HBV replication, wherein the upregulation of lncRNA HOXA‐AS2, induced by HBV DNA pol, can epigenetically suppress cccDNA transcription.
Hemodynamic Bedside Monitoring Instrument with Pressure and Optical Sensors: Validation and Modality Comparison
Authors: Kaisti Matti , Panula Tuukka , Sirkiä Jukka‐Pekka , Pänkäälä Mikko , Koivisto Tero , Niiranen Teemu , Kantola Ilkka 
Published: April 2024

AbstractResults from two independent clinical validation studies for measuring hemodynamics at the patient's bedside using a compact finger probe are reported. Technology comprises a barometric pressure sensor, and in one implementation, additionally, an optical sensor for photoplethysmography (PPG) is developed, which can be used to measure blood pressure and analyze rhythm, including the continuous detection of atrial fibrillation. The capabilities of the technology are shown in several form factors, including a miniaturized version resembling a common pulse oximeter to which the technology could be integrated in. Several main results are presented: i) the miniature finger probe meets the accuracy requirements of non‐invasive blood pressure instrument validation standard, ii) atrial fibrillation can be detected during the blood pressure measurement and in a continuous recording, iii) a unique comparison between optical and pressure sensing mechanisms is provided, which shows that the origin of both modalities can be explained using a pressure‐volume model and that recordings are close to identical between the sensors. The benefits and limitations of both modalities in hemodynamic monitoring are further discussed.
Antimicrobial and Antiviral Nanofibers Halt Co‐Infection Spread via Nuclease‐Mimicry and Photocatalysis
Authors: Yao Jieran , Luo Zhenhong , Lin Jiaying , Meng Na , Guo Jiangna , Xu Hui , Shi Rongwei , Zhao Linhui , Zhou Jiateng , Yan Feng , Wang Bin , Mao Hailei 
Published: April 2024

AbstractThe escalating spread of drug‐resistant bacteria and viruses is a grave concern for global health. Nucleic acids dominate the drug‐resistance and transmission of pathogenic microbes. Here, imidazolium‐type poly(ionic liquid)/porphyrin (PIL‐P) based electrospun nanofibrous membrane and its cerium (IV) ion complex (PIL‐P‐Ce) are developed. The obtained PIL‐P‐Ce membrane exhibits high and stable efficiency in eradicating various microorganisms (bacteria, fungi, and viruses) and decomposing microbial antibiotic resistance genes and viral nucleic acids under light. The nuclease‐mimetic and photocatalytic mechanisms of the PIL‐P‐Ce are elucidated. Co‐infection wound models in mice with methicillin‐resistant S. aureus and hepatitis B virus demonstrate that PIL‐P‐Ce integrate the triple effects of cationic polymer, photocatalysis, and nuclease‐mimetic activities. As revealed by proteomic analysis, PIL‐P‐Ce shows minimal phototoxicity to normal tissues. Hence, PIL‐P‐Ce has potential as a “green” wound dressing to curb the spread of drug‐resistant bacteria and viruses in clinical settings.
Light‐Intensity Switching of Graphene/WSe2 Synaptic Devices
Authors: Tang Hongyu , Anwar Tarique , Jang Min Seok , Tagliabue Giulia 
Published: April 2024

Abstract2D van der Waals heterojunctions (vdWH) have emerged as an attractive platform for the realization of optoelectronic synaptic devices, which are critical for energy‐efficient computing systems. Photogating induced by charge traps at the interfaces indeed results in ultrahigh responsivity and tunable photoconductance. Yet, optical potentiation and depression remain mostly modulated by gate bias, requiring relatively high energy inputs. Thus, advanced all‐optical synapse switching strategies are still needed. In this work, a reversible switching between positive photoconductivity (PPC) and negative photoconductivity (NPC) is achieved in graphene/WSe2 vdWH solely through light‐intensity modulation. Consequently, the graphene/WSe2 synaptic device shows tunable optical potentiation and depression behavior with an ultralow power consumption of 127 aJ. The study further unravels the complex interplay of gate bias and incident light power in determining the sign and magnitude of the photocurrent, showing the critical role of charge trapping and photogating at interfaces. Interestingly, it is found that switching between PPC to NPC can be also obtained at 0 mV drain‐source voltage. Overall, the reversible potentiation/depression effect based on light intensity modulation and its combination with additional gate bias tunability is very appealing for the development of energy‐efficient optical communications and neuromorphic computing.
Non‐Invasive Hemodynamic Monitoring System Integrating Spectrometry, Photoplethysmography, and Arterial Pressure Measurement Capabilities
Authors: Sirkiä Jukka‐Pekka , Panula Tuukka , Kaisti Matti 
Published: April 2024

AbstractMinimally invasive and non‐invasive hemodynamic monitoring technologies have recently gained more attention, driven by technological advances and the inherent risk of complications in invasive techniques. In this article, an experimental non‐invasive system is presented that effectively combines the capabilities of spectrometry, photoplethysmography (PPG), and arterial pressure measurement. Both time‐ and wavelength‐resolved optical signals from the fingertip are measured under external pressure, which gradually increased above the level of systolic blood pressure. The optical channels measured at 434–731 nm divided into three groups separated by a group of channels with wavelengths approximately between 590 and 630 nm. This group of channels, labeled transition band, is characterized by abrupt changes resulting from a decrease in the absorption coefficient of whole blood. External pressure levels of maximum pulsation showed that shorter wavelengths (<590 nm) probe superficial low‐pressure blood vessels, whereas longer wavelengths (>630 nm) probe high‐pressure arteries. The results on perfusion indices and DC component level changes showed clear differences between the optical channels, further highlighting the importance of wavelength selection in optical hemodynamic monitoring systems. Altogether, the results demonstrated that the integrated system presented has the potential to extract new hemodynamic information simultaneously from macrocirculation to microcirculation.
2D Halide Perovskites for High‐Performance Resistive Switching Memory and Artificial Synapse Applications
Authors: Li Bixin , Xia Fei , Du Bin , Zhang Shiyang , Xu Lan , Su Qiong , Zhang Dingke , Yang Junliang 
Published: April 2024

AbstractMetal halide perovskites (MHPs) are considered as promising candidates in the application of nonvolatile high‐density, low‐cost resistive switching (RS) memories and artificial synapses, resulting from their excellent electronic and optoelectronic properties including large light absorption coefficient, fast ion migration, long carrier diffusion length, low trap density, high defect tolerance. Among MHPs, 2D halide perovskites have exotic layered structure and great environment stability as compared with 3D counterparts. Herein, recent advances of 2D MHPs for the RS memories and artificial synapses realms are comprehensively summarized and discussed, as well as the layered structure properties and the related physical mechanisms are presented. Furthermore, the current issues and developing roadmap for the next‐generation 2D MHPs RS memories and artificial synapse are elucidated.
A Scalable and Robust Personal Health Management Textile with Multiple Desired Thermal Functions and Electromagnetic Shielding
Authors: Tang Litao , Lyu Bin , Gao Dangge , Zhou Yingying , Wang Yunchuan , Wang Fangxing , Jia Zhangting , Fu Yatong , Chen Ken , Ma Jianzhong 
Published: April 2024

AbstractThe development of functional textiles combining conventional apparel with advanced technologies for personal health management (PHM) has garnered widespread attention. However, the current PHM textiles often achieve multifunctionality by stacking functional modules, leading to poor durability and scalability. Herein, a scalable and robust PHM textile is designed by integrating electrical, radiative, and solar heating, electromagnetic interference (EMI) shielding, and piezoresistive sensing performance onto cotton fabric. This is achieved through an uncomplicated screen‐printing process using silver paste. The conductivity of the PHM textile is ≈1.6  × 104 S m−1, ensuring an electric heating temperature of ≈134 °C with a low voltage of 1.7 V, as well as an EMI shielding effectiveness of ≈56 dB, and human motion monitoring performance. Surprisingly, the radiative/solar heating capability of the PHM textile surpasses that of traditional warm leather. Even after undergoing rigorous physical and chemical treatments, the PHM textile maintains terrific durability. Additionally, the PHM textile possesses maneuverable scalability and comfortable wearability. This innovative work opens up new avenues for the strategic design of PHM textiles and provides an advantageous guarantee of mass production.
Advanced Multifunctional Hydrogels for Enhanced Wound Healing through Ultra‐Fast Selenol‐SNAr Chemistry
Authors: Wu Yan , Bei Ying , Li Wenjing , Lu Weihong , Zhu Jian , Zhang Zhengbiao , Zhang Tinglin , Liu Sen , Chen Kaiyuan , Jin Hong , Li Luxin , Li Meng , Gao Jie , Pan Xiangqiang 
Published: April 2024

AbstractFabrication of versatile hydrogels in a facile and effective manner represents a pivotal challenge in the field of biomaterials. Herein, a novel strategy is presented for preparing on‐demand degradable hydrogels with multilevel responsiveness. By employing selenol‐dichlorotetrazine nucleophilic aromatic substitution (SNAr) to synthesize hydrogels under mild conditions in a buffer solution, the necessity of additives or posttreatments can be obviated. The nucleophilic and redox reactions between selenol and tetrazine culminate in the formation of three degradable chemical bonds—diselenide, aryl selenide, and dearomatized selenide—in a single, expeditious step. The resultant hydrogel manifests exceptional adaptability to intricate environments in conjunction with self‐healing and on‐demand degradation properties. Furthermore, the resulting material demonstrated light‐triggered antibacterial activity. Animal studies further underscore the potential of integrating metformin into Se‐Tz hydrogels under green light irradiation, as it effectively stimulates angiogenesis and collagen deposition, thereby fostering efficient wound healing. In comparison to previously documented hydrogels, Se‐Tz hydrogels exhibit controlled degradation and drug release, outstanding antibacterial activity, mechanical robustness, and bioactivity, all without the need for costly and intricate preparation procedures. These findings underscore Se‐Tz hydrogels as a safe and effective therapeutic option for diabetic wound dressings.
Facile Lithium Densification Kinetics by Hyperporous/Hybrid Conductor for High‐Energy‐Density Lithium Metal Batteries
Authors: Han Dong‐Yeob , Kim Saehun , Nam Seoha , Lee Gayoung , Bae Hongyeul , Kim Jin Hong , Choi Nam‐Soon , Song Gyujin , Park Soojin 
Published: April 2024

AbstractLithium metal anode (LMA) emerges as a promising candidate for lithium (Li)‐based battery chemistries with high‐energy‐density. However, inhomogeneous charge distribution from the unbalanced ion/electron transport causes dendritic Li deposition, leading to “dead Li” and parasitic reactions, particularly at high Li utilization ratios (low negative/positive ratios in full cells). Herein, an innovative LMA structural model deploying a hyperporous/hybrid conductive architecture is proposed on single‐walled carbon nanotube film (HCA/C), fabricated through a nonsolvent induced phase separation process. This design integrates ionic polymers with conductive carbon, offering a substantial improvement over traditional metal current collectors by reducing the weight of LMA and enabling high‐energy‐density batteries. The HCA/C promotes uniform lithium deposition even under rapid charging (up to 5 mA cm−2) owing to its efficient mixed ion/electron conduction pathways. Thus, the HCA/C demonstrates stable cycling for 200 cycles with a low negative/positive ratio of 1.0 when paired with a LiNi0.8Co0.1Mn0.1O2 cathode (areal capacity of 5.0 mAh cm−2). Furthermore, a stacked pouch‐type full cell using HCA/C realizes a high energy density of 344 Wh kg−1cell/951 Wh L−1cell based on the total mass of the cell, exceeding previously reported pouch‐type full cells. This work paves the way for LMA development in high‐energy‐density Li metal batteries.
Fundamental Aspects of Conduction in Charged ErMnO3 Domain Walls
Authors: McCartan James , Turner Patrick W. , McConville James P. V. , Holsgrove Kristina , Cochard Charlotte , Kumar Amit , McQuaid Raymond G. P. , Meier Dennis , Gregg J. Marty 
Published: April 2024

AbstractIt is now well‐established that ferroelectric domain walls, at which there are discontinuities in polarization, are usually electrically conducting. Yet, there is a dearth of rather basic information on the physics underpinning conductivity. Here, Kelvin Probe Force Microscopy (KPFM)‐based experiments are reported, which allow significant new insights regarding charge transport at domain walls in ErMnO3. In one set of experiments, KPFM is used to spatially map the Hall potential, developed at the surface of polished single crystals. These maps provide direct experimental evidence that n‐type head‐to‐head domain walls arise in otherwise p‐type material. In another set of experiments, the geometry for current flow is restricted, by cutting sub‐micron thick lamellar slices of ErMnO3 (using a Focused Ion Beam microscope). Separate contacts are made to n and p‐type walls and the potential profiles, when driving source‐drain currents, are measured (again using KPFM). Current‐electric field functions showed Ohmic behaviour for p‐type walls, with an intrinsic room temperature conductivity value of ≈0.4Sm−1. The n‐type walls showed non‐Ohmic behaviour and a significantly lower conductivity, supporting the prediction that electrons are in a polaronic state; an upper bound for the room temperature conductivity of the domains themselves is ≈6 × 10−6Sm−1 at 0.1 MVm−1.