bluuebunny/crossref_metadata_2025_split huggingface dataset:
Equine paranasal sinus disease: A long‐term study of 200 cases (1997–2009): Ancillary diagnostic findings and involvement of the various sinus compartments
Authors: DIXON P. M. , PARKIN T. D. , COLLINS N. , HAWKES C. , TOWNSEND N. , TREMAINE W. H. , FISHER G. , EALEY R. , BARAKZAI S. Z. 
Published: August 2011

SummaryReasons for performing study: There is a lack of objective information on the value of ancillary diagnostic techniques used to investigate equine sinus disease, and also on which sinus compartments are commonly affected in this disorder.Objectives: To record the ancillary diagnostic findings used to investigate equine sinus disease and to document which compartments are affected.Materials and methods: The clinical case records of 200 consecutive cases of sinus disease, including subacute (<2 months' duration) primary (n = 52); chronic (>2 months' duration) primary (n = 37); dental (n = 40); traumatic (n = 13); sinus cyst (n = 26); sinus neoplasia (n = 10); dental related oromaxillary fistula (n = 8); mycotic sinusitis (n = 7) and intra‐sinus progressive ethmoid haematoma (n = 7) were retrospectively examined.Results: Nasal endoscopy showed exudate draining from the sino‐nasal ostia in 88% of cases and a sino‐nasal fistula was present in 15% of cases. Sinoscopy was performed in 79% of cases and was of great diagnostic value. More recently, 22% of cases had fenestration of the ventral conchal bulla performed to allow sinoscopy of the rostral sinus compartments. Radiography was performed in 97% of cases and showed intra‐sinus fluid lines to be common (69% prevalence) in subacute primary sinusitis. Radiographic dental apical changes were not specific to dental sinusitis, e.g. 29% of chronic primary sinusitis cases had radiographic dental changes. Scintigraphy was performed in 20% of cases and was helpful in identifying dental apical changes when radiography was inconclusive. Overall, the caudal maxillary (78% involvement) and rostral maxillary (61%) sinuses were most commonly affected, with the ventral conchal sinus (VCS) (54% involvement) and conchofrontal sinuses (48%) less so. The VCS showed the greatest tendency to contain inspissated pus (present in 46% of all affected VCS).Conclusions: Nasal endoscopy, sinoscopy and skull radiography are of great value in diagnosing the presence and causes of equine sinus disease.
Equine paranasal sinus disease: A long‐term study of 200 cases (1997–2009): Treatments and long‐term results of treatments
Authors: DIXON P. M. , PARKIN T. D. , COLLINS N. , HAWKES C. , TOWNSEND N. , TREMAINE W. H. , FISHER G. , EALEY R. , BARAKZAI S. Z. 
Published: August 2011

SummaryReasons for performing study:There is limited objective information available on the treatment and the long‐term response to treatment of the different types of equine sinus disease.Objectives:To document the treatments and long‐term response to these treatments in 200 cases of equine sinus disease (1997–2009).Methods:The treatments of horses affected with subacute primary sinusitis (n = 52); chronic primary sinusitis (n = 37); dental sinusitis (n = 40); sinus cyst (n = 26); traumatic (n = 13); dental‐related oromaxillary fistula (n = 8); sinus neoplasia (n = 10); mycotic sinus disease (n = 7); and intrasinus progressive ethmoid haematoma (n = 7) and the long‐term response to these treatments were retrospectively reviewed.Results:Treatments evolved throughout the study and latterly were as conservative as possible, including sinoscopic lavage and standing sinusotomy, with a maxillary sinusotomy approach preferred for the mainly mature horses treated in this study. Removal of intrasinus inspissated pus, including transendoscopically (by sinusotomy and via existing sinonasal fistulae), was the main treatment for chronic primary sinusitis and sinonasal fistulation was seldom performed latterly. Attempted oral extraction of infected cheek teeth, even if unsuccessful, facilitated subsequent dental repulsion, resulting in few post operative problems. Sinus cyst removal carried an excellent prognosis. Except for cases of sinus neoplasia (only 22% cured), an excellent long‐term response to treatment (91% fully cured, 7% partially cured) was obtained for all other types of sinus disease following a median of one treatment.Conclusions:More conservative treatments, including removal of intrasinus inspissated pus by sinoscopy, pre‐existing sinonasal fistula or sinusotomy, are effective for chronic primary sinus disease. Standing sinusotomy, mainly using a small maxillary site, was suitable for most cases of sinus disease in mature horses.
Pythium aphanidermatum Infection following Combat Trauma
Authors: Calvano Tatjana P. , Blatz Peter J. , Vento Todd J. , Wickes Brian L. , Sutton Deanna A. , Thompson Elizabeth H. , White Christopher E. , Renz Evan M. , Hospenthal Duane R. 
Published: August 2011

ABSTRACT

Pythium aphanidermatum
is a fungus-like plant pathogen which has never been reported as a cause of human infection. We report a case of
P. aphanidermatum
invasive wound infection in a 21-year-old male injured during combat operations in Afghanistan.
Pyrosequencing for Rapid Molecular Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Strains and Clinical Specimens
Authors: García-Sierra N. , Lacoma A. , Prat C. , Haba L. , Maldonado J. , Ruiz-Manzano J. , Gavin P. , Samper S. , Ausina V. , Domínguez J. 
Published: August 2011

ABSTRACT

The aim of this study was to evaluate a pyrosequencing method for the detection of
Mycobacterium tuberculosis
isolates resistant to rifampin and isoniazid using both clinical strains and clinical samples, comparing the results with those of the Bactec 460TB and GenoType MTBDR
plus
assays. In comparison to Bactec 460TB as the gold standard, the sensitivity of pyrosequencing for detecting isoniazid and rifampin resistance was 76.9% and 97.2%, respectively, for clinical strains, and the specificity was 97.2 and 97.9%, respectively. For clinical specimens, the sensitivity and specificity for both drugs were 85.7% and 100%, respectively. The overall concordance between pyrosequencing and the GenoType MTBDR
plus
assay for clinical strains was 99.1%, and for clinical samples, it was 98.2%. Pyrosequencing is a valuable tool for rifampin and isoniazid resistance detection.
Lifestyle and self-rated health: a cross-sectional study of 3,601 citizens of Athens, Greece
Authors: Darviri Christina , Artemiadis Artemios K , Tigani Xanthi , Alexopoulos Evangelos C 
Published: August 2011

AbstractBackgroundSelf-rated health (SRH) is a popular health measure determined by multiple factors. International literature is increasingly focusing on health-related behaviors such as smoking, dietary habits, physical activity, even religiosity. However, population-based studies taking into account multiple putative determinants of SRH in Greece are scarce. The aim of this study was to clarify possible determinants of SRH with an emphasis on the relationship between SRH and lifestyle variables in a large sample of urban citizens.MethodsIn this one-year cross-sectional study, a stratified random sample of 3,601 urban citizens was selected. Data were collected using an interview-based questionnaire about various demographic, socioeconomic, disease- and lifestyle related factors such as smoking, physical activity, dietary habits, sleep quality and religiosity. Multivariate logistic regression was used separately in three age groups [15-29 (N = 1,360), 30-49 (N = 1,122) and 50+ (N = 1,119) years old] in order to identify putative lifestyle and other determinants of SRH.ResultsReporting of good SRH decreased with age (97.1%, 91.4% and 74.8%, respectively). Overall, possible confounders of the lifestyle-SRH relationship among age groups were sex, education, hospitalization during the last year, daily physical symptoms and disease status. Poor SRH was associated with less physical activity in the 15-29 years old (OR 2.22, 95%CI 1.14-4.33), with past or heavy smoking, along with no sleep satisfaction in the 30-49 years old (OR 3.23, 95%CI 1.35-7.74, OR 2.56, 95%CI 1.29-5.05, OR 1.79, 95%CI 1.1-2.92, respectively) and with obesity and no sleep satisfaction in the 50+ years old individuals (OR 1.83, 95%CI 1.19-2.81, OR 2.54, 95%CI 1.83-3.54). Sleep dissatisfaction of the 50+ years old was the only variable associated with poor SRH at the 0.001 p level of significance (OR 2.45, 99%CI 1.59 to 3.76). Subgroup analyses of the 15-19 years old individuals also revealed sleep dissatisfaction as the only significant variable correlated with SRH.ConclusionsSlight differences in lifestyle determinants of SRH were identified among age groups. Sleep quality emerged as an important determinant of SRH in the majority of participants.
Chemical and biological evaluation of scandium(III)-polyaminopolycarboxylate complexes as potential PET agents and radiopharmaceuticals
Authors: Huclier-Markai S. , Sabatie A. , Ribet S. , Kubícek V. , Paris M. , Vidaud C. , Hermann P. , Cutler C. S. 
Published: August 2011

Abstract
Scandium isotopes (44Sc, 47Sc) are more available and their properties are convenient for either PET imaging or radiotherapy. To use them in nuclear medicine, ligands forming complexes with a high stability are necessary. Available experimental data on stability constants for complexes of ligands such as EDTA, DTPA, DOTA, NOTA and TETA with various metal ions have been published. But scandium is the exception since scarce data is available in the literature. Values of stability constants of Sc(III) with the ligands were determined by free-ion selective radiotracer extraction, complemented by 45Sc NMR and potentiometry data. The thermodynamic stability of the Sc-complexes increases in the order TETA < NOTA < EDTA < DTPA < DOTA. The in vitro stability of the Sc(III) complexes was studied in the presence of hydroxyapatite and rat serum to estimate their in vivo stability. The most stable complex was shown to be Sc-DOTA.
Optical and Crystallographic Studies of Ion-Implanted Relaxor Ferroelectric Lead Zinc Niobate for Single-Crystal Layer Transfer
Authors: Levy M. , Moran P. D. 
Published: August 2011

AbstractLayer separation of He+-ion implanted relaxor ferroelectric films (0.955)[Pb(Zn1/3Nb2/3)O3]–(0.045)[PbTiO3] (0.955PZN-0.045PT) has recently been reported in the literature.[1,2] Here we report on optical and X-ray diffraction analysis of the implanted material prior to separation. The formation of optical waveguides as a result of He+-ion implantation enables us to probe the sacrificial layer. A large refractive index contrast is observed between this layer and the film. Significant tetragonal distortions are also seen in the waveguide region (“the film”). Rapid thermal processing (RTP) significantly changes the peak position of the index contrast profile, possibly indicating a large redistribution of stress by He evolution in the sacrificial layer. A commensurate reduction in tetragonal distortion and local strain distribution in the waveguide region to values close to those observed before implantation is measured by triple crystal high resolution X-ray diffraction.
Prominent Decrease of Superior Midperipheral Endothelial Cell Density After Iris-fixated Phakic Intraocular Lens Implantation
Authors: Kim Jae Hoon , Choi Bong Joon , Roh Hyunseok , Kim Eung Kweon , Kim Tae-im 
Published: August 2011

PURPOSE:
To evaluate changes in endothelial cell density (ECD) in the corneal region after implantation of an iris-fixated phakic intraocular lens (PIOL).

METHODS:
Forty-five eyes of 25 myopic patients implanted with Artisan iris-fixated PIOLs (Ophtec BV) and 30 eyes of 15 myopic controls were enrolled. Corneal ECD and the distance between endothelium and the PIOL optic were evaluated in five different regions (central, nasal, superior, temporal, and inferior) using noncontact specular microscopy and rotating Scheimpflug imaging.

RESULTS:
In PIOL-implanted patients, significant differences between the ECD in the superior region, compared with the lowest ECD in any region, and the ECD of the central region, compared with that of the region with highest ECD, were evident. When PIOL-implanted eyes were divided based on time since operation, a significant difference was observed only in patients for whom at least 48 postoperative months had elapsed. In untreated myopic controls, the greatest ECD was observed at the superior cornea. The distance between the central corneal endothelium and PIOL was significantly longer than that of the peripheral locations.

CONCLUSIONS:
The extent of ECD decrease was not consistent throughout the cornea after implantation of an iris-fixated PIOL. Therefore, ECD measurement not only at the corneal center but also at midperipheral corneal locations, especially in the superior cornea, may be important in patients with irisfixated PIOLs.
ChemInform Abstract: Palladium‐Catalyzed, One‐Pot , Three‐Component Approach to α‐Alkynyl Indoles from o‐Bromo‐(2,2‐dibromovinyl)benzenes, Terminal Alkynes and Arylamines.
Authors: Liang Yun , Meng Tianhao , Zhang Hui‐Jun , Xi Zhenfeng 
Published: August 2011

AbstractA variety of alkynyl indoles is obtained from polyhalo compounds (I) and (VIII), arylamines (II) and (V), and alkynes (III) and (VI).
Leukoflow: Multiparameter extended white blood cell differentiation for routine analysis by flow cytometry
Authors: van de Geijn Gert‐Jan , van Rees Vincent , van Pul‐Bom Natasja , Birnie Erwin , Janssen Hans , Pegels Hans , Beunis Marlène , Njo Tjin 
Published: July 2011

AbstractDifferential white blood cell count (dWBC) is a frequently used diagnostic tool. For most patient samples an automated blood counter produces a five‐part differential count. If this dWBC does not meet pre‐set criteria, microscopic dWBC is performed. Microscopy is labor intensive and requires sustained training of technicians. Inter‐observer variation and statistical variation are significant, due to limited numbers of cells counted. Flow cytometry is a candidate reference method for dWBC. Advantages are immunological definitions and large number of measured cells. Our goal was to replace (part of) the microscopic dWBC by a flow cytometric dWBC, that gives additional information on blasts, myeloid precursors, and lymphocyte subsets. We designed a cocktail of antibodies (CD4, CD14, CD34, CD16, CD56, CD19, CD45, CD138, CD3, and CD71) combined with a gating strategy and flow cytometric protocol for easy identification of leukocyte populations. This assay, called Leukoflow, requires low sample volume, has few manual handling steps, and a potential turn‐around‐time shorter than 2 h. We determine percentages and absolute concentrations of at least 13 different cell populations. For quantification of normoblasts a second flow cytometric staining was designed. We compared microscopic dWBC with that of the automated blood counter and Leukoflow for normal and abnormal blood samples. Leukoflow results correlate well with the automated blood counter for leukocytes, neutrophils, eosinophils, monocytes, and lymphocytes. Correlation with manual dWBC is lower. Blast counts reported by Leukoflow suffer less from inter‐observer variation compared to manual dWBC. In addition to microscopic or cytometric dWBC‐techniques T‐lymphocytes, CD4‐T‐lymphocytes, B‐lymphocytes, NK‐cells, myeloid progenitors, plasma cells, and blasts are determined by Leukoflow. These populations give potential useful clinical information and are subject for future studies focusing on the additional clinical value. Leukoflow is a highly interesting and promising technique for clinical laboratories. © 2011 International Society for Advancement of Cytometry
Relation between volumetric changes of unsaturated polyester resin and surface finish quality of fiberglass/unsaturated polyester composite panels
Authors: Khoun Loleï , Palardy Geneviève , Hubert Pascal 
Published: August 2011

AbstractResin dimensional changes, including cure shrinkage and thermal expansion, highly influence the surface finish quality of composite parts. Low profile additives (LPA) are commonly incorporated in unsaturated polyester (UP) resins to compensate for resin shrinkage and obtain a high quality surface finish. In this study, the dimensional change of an UP resin with different LPA contents was characterized. Both resin cure shrinkage and resin thermal expansion were measured. A simple methodology was then developed to estimate the surface finish quality of panels, manufactured by resin transfer molding (RTM), based on the prediction of part thickness variation during the process. Results show good agreement with the experimental investigations. POLYM. COMPOS., 2011. © 2011 Society of Plastics Engineers
Selective neurocognitive impairments in adolescents with major depressive disorder
Authors: Han Georges , Klimes‐Dougan Bonnie , Jepsen Susie , Ballard Kristin , Nelson Megan , Houri Alaa , Kumra Sanjiv , Cullen Kathryn 
Published: July 2011

ABSTRACTThis study investigated whether major depression in adolescence is characterized by neurocognitive deficits in attention, affective decision making, and cognitive control of emotion processing. Neuropsychological tests including the Wechsler Abbreviated Scale of Intelligence, the Continuous Performance Test–Identical Pairs, the Attention Network Test, the Iowa Gambling Task, the Emotional Go‐NoGo Task, and the Face Go‐NoGo Task were administered to adolescents with Major Depressive Disorder (MDD) (n = 31) and psychiatric diagnosis free controls (n = 30). Findings indicated that compared with controls, depressed adolescents exhibited impaired sustained attention; a gender by group interaction on affective decision making such that depressed males tended to make less advantageous choices on the IGT; and an inverse pattern of correlations between depressive symptom counts and reaction time to affective stimuli, characterizing greater affective reactivity in depressed adolescents. Findings demonstrate that adolescents with MDD display selective neurocognitive impairments on tasks capturing ‘cool’ and ‘hot’ executive functioning.
Falls in Multiple Sclerosis
Authors: Matsuda Patricia N. , Shumway‐Cook Anne , Bamer Alyssa M. , Johnson Shana L. , Amtmann Dagmar , Kraft George H. 
Published: July 2011

ObjectiveTo examine incidence, associated factors, and health care provider (HCP) response to falls in persons with multiple sclerosis (MS).DesignCross‐sectional retrospective design.SettingCommunity setting.ParticipantsFour hundred seventy‐four persons with MS.MethodsMailed survey questionnaire examined incidence, risk factors, and HCP response to falls in persons with MS who were dwelling in the community. Univariate and multiple ordinal regression analysis identified variables associated with single and multiple falls.Main Outcome MeasurementsFalls, causes and perceived reasons for falls, and HCP response.ResultsA total of 265 participants (58.2%) reported one or more falls in the previous 6 months, and 58.5% of falls were medically injurious. Trips/slips while walking accounted for 48% of falls. Factors associated with falls included use of a cane or walker (odds ratio [OR] 2.62; 95% confidence interval [CI] 1.66‐4.14), income <$25,000 (OR 1.85; 95% CI 1.13‐3.04), balance problems (OR 1.28; 95% CI 1.11‐1.49), and leg weakness (OR 1.26; 95% CI 1.09‐1.46). Fifty‐one percent of those who fell (135/265) reported speaking to an HCP about their falls; recommended strategies included safety strategies (53.2%), use of gait assistive devices (42.1%), exercise/balance training (22.2%), and home modifications (16.6%).ConclusionsFactors associated with falls in persons with MS are similar to those in other populations with neurologic diseases. Despite the high incidence of falls, fewer than 50% of people with MS receive information about prevention of falls from an HCP.
Proceedings From the Ice Hockey Summit on Concussion: A Call to Action
Authors: Smith Aynsley M. , Stuart Michael J. , Greenwald Richard M. , Benson Brian W. , Dodick David W. , Emery Carolyn , Finnoff Jonathan T. , Mihalik Jason P. , Roberts William O. , Sullivan Carol‐Anne , Meeuwisse Willem H. 
Published: July 2011

ObjectiveThe objective of this proceeding is to integrate the concussion in sport literature and sport science research on safety in ice hockey to develop an action plan to reduce the risk, incidence, severity, and consequences of concussion in ice hockey.MethodsA rationale paper outlining a collaborative action plan to address concussions in hockey was posted for review 2 months before the Ice Hockey Summit: Action on Concussion. Focused presentations devoted specifically to concussion in ice hockey were presented during the Summit, and breakout sessions were used to develop strategies to reduce concussion in the sport. This proceedings and a detailed scientific review (a matrix of solutions) were written to disseminate the evidence‐based information and resulting concussion reduction strategies. The manuscripts were reviewed by the authors, advisers, and contributors to ensure that the opinions and recommendations reflect the current level of knowledge on concussion in hockey.ResultsSix components of a potential solution were articulated in the Rationale paper and became the topics for breakout groups that followed the professional, scientific lectures. Topics that formed the core of the action plan were metrics and databases; recognizing, managing, and returning to play; hockey equipment and ice arenas; prevention and education; rules and regulations; and expedient communication of the outcomes. The attendees in breakout sessions identified action items for each section. The most highly ranked action items were brought to a vote in the open assembly by using an Audience Response System. The strategic planning process was conducted to assess the following: Where are we at? Where must we get to? What strategies are necessary to make progress on the prioritized action items?ConclusionsThree prioritized action items for each component of the solution and the percentage of the votes received are listed in the body of this proceeding.
An Iron Age Mirror from Ruxox, Maulden, Bedfordshire
Authors: Burleigh Gilbert , Megaw Vincent 
Published: July 2011

AbstractThis short note puts on record three fragments of an Iron Age decorated mirror found in 1998 in a field near Ruxox Farm, in the parish of Maulden, Bedfordshire, the fifth such mirror to be recorded from that county. The significance of the find is discussed within the context of the overall archaeology of the Ruxox area and compared to other mirror finds from the region.
THE CLASSIFICATION OF SOME MODULAR FROBENIUS GROUPS
Authors: FAN JUANJUAN , DU NI , ZENG JIWEN 
Published: July 2011

AbstractFix a prime number p. Let G be a p-modular Frobenius group with kernel N which is the minimal normal subgroup of G. We give the complete classification of G when N has three, four or five p-regular conjugacy classes. We also determine the structure of G when N has more than five p-regular conjugacy classes.