bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co@C Nanocatalyst: Enhanced Activation of Peroxymonosulfate for Paracetamol Degradation
Authors: Guan Xiaotong , Li Liang , Jiang Yu , Zheng Boyu , Gu Xinyue , Liu Yuelei , Yu Lai 
Published: May 2024

A core–shell Co@C composite catalyst was prepared, characterized and used to activate peroxymonosulfate (PMS) for the degradation of paracetamol in water. Hybridized structures containing Co and graphitized carbon act as independent active sites for PMS activation initiating both radical and nonradical oxidation. A 91.57% paracetamol removal was reached in the Co@C/PMS system at 60 min. Radical quenching and electron paramagnetic resonance (EPR) tests show that nonradical 1O2 played predominant roles in the advanced oxidation process, while the other three radicals [Formula: see text], •OH and [Formula: see text]. also played a certain role in paracetamol degradation. After four cycles, the degradation could still reach 70%, which proves that the Co@C composite catalyst exhibits good stability.
Avoiding the ‘Backfire Problem’: How Martin Luther King Jr. came to Ground his Nonviolent Activism in Personalism
Authors: Wilson Paul E. 
Published: May 2024

Abstract
Dr. Martin Luther King Jr. appears to have preferred nonviolent tactics for social justice that sidestepped the backfire problem. Given that he deployed approximately twenty-five nonviolent tactics, the number of options he chose not to deploy greatly outnumbers those he did deploy. Why? Both his circumstances and his philosophy shaped his preferences for nonviolent tactics. First, I explore how his preferred tactics embodied the praxis of his nonviolent personalism. Second, I explore the early introduction of King to pacifism and how this evolved during his graduate studies at Boston University. Third, I suggest that King drew upon his commitment to personalism to develop pragmatically his own approach to nonviolent activism, and that when King visited India, he was seeking practical support for his praxis of nonviolent activism. Finally, I reflect on how King’s praxis of nonviolent activism aimed to avoid the backfire problem.
Performance and Return to Play After Surgery for Thoracic Outlet Syndrome in Professional Baseball Players: A Matched Cohort Analysis
Authors: Chauhan Aakash , Chalmers Peter N. , Erickson Brandon J. , Thompson Robert , Pearl Gregory J. , Romeo Anthony A. , Hoenecke Heinz R. , Ma Kevin , Tenner Zachary , Fronek Jan 
Published: May 2024

Background: Thoracic outlet syndrome (TOS) remains a rare diagnosis but is being recognized as a cause of upper extremity dysfunction in professional baseball players. Purpose/Hypothesis: The purpose was to determine performance and return-to-play (RTP) outcomes in professional baseball players after surgical treatment of TOS. The hypothesis was that there would be a high RTP rate in professional baseball players after TOS surgery with no statistical differences in performance between pitchers who had TOS surgery and matched controls. Study Design: Cohort study; Level of evidence, 3. Methods: All professional baseball players who underwent surgical treatment of TOS between 2010 and 2017 were identified using the Major League Baseball Health and Injury Tracking System database. Demographic and performance data (before and after surgery) for each player were recorded. Performance variables were then compared between players who underwent TOS surgery and matched controls. The matching criteria were no history of previous surgeries on affected arm, age at time of surgery, throwing side, level of play (Major or Minor League Baseball), and years of experience playing professional baseball. Results: Overall, 52 players underwent surgery for TOS, of whom 46 (88%) were pitchers. The type of TOS was neurogenic in 69% and venous in 29%. One player had arterial TOS. After TOS surgery, 79% of players returned to play at the same or higher level (RTSP) by 9.5 months and played ≥3 years after surgery. No differences were found in RTSP rate based on the type of TOS. No statistical difference was found in RTP rates between major and minor league players. Pitchers had a 76% RTSP, which was similar to the natural attrition for control pitchers ( P = .874). After TOS surgery, pitchers saw a decline in several performance metrics, but these declines were not different from those of control pitchers, indicating that the decline in performance after TOS surgery was no faster than is seen in healthy professional pitchers as they age. Conclusion: The rate of RTSP after surgery for TOS in professional baseball players was 79%. There was no difference in RTP based on the type of TOS. Pitchers who underwent surgery for TOS had no significant differences in pitching performance metrics after surgery compared with matched controls.
Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease
Authors: Savvopoulos Symeon , Hatzikirou Haralampos , Jelinek Herbert F 
Published: May 2024

Background: Type 2 diabetes mellitus (T2DM) are 90% of diabetes cases, and its prevalence and incidence, including comorbidities, are rising worldwide. Clinically, diabetes and associated comorbidities are identified by biochemical and physical characteristics including glycemia, glycated hemoglobin (HbA1c), and tests for cardiovascular, eye and kidney disease. Objectives: Diabetes may have a common etiology based on inflammation and oxidative stress that may provide additional information about disease progression and treatment options. Thus, identifying high-risk individuals can delay or prevent diabetes and its complications. Design: In patients with or without hypertension and cardiovascular disease, as part of progression from no diabetes to T2DM, this research studied the changes in biomarkers between control and prediabetes, prediabetes to T2DM, and control to T2DM, and classified patients based on first-attendance data. Control patients and patients with hypertension, cardiovascular, and with both hypertension and cardiovascular diseases are 156, 148, 61, and 216, respectively. Methods: Linear discriminant analysis is used for classification method and feature importance, This study examined the relationship between Humanin and mitochondrial protein (MOTSc), mitochondrial peptides associated with oxidative stress, diabetes progression, and associated complications. Results: MOTSc, reduced glutathione and glutathione disulfide ratio (GSH/GSSG), interleukin-1β (IL-1β), and 8-isoprostane were significant ( P < .05) for the transition from prediabetes to t2dm, highlighting importance of mitochondrial involvement. complement component 5a (c5a) is a biomarker associated with disease progression and comorbidities, gsh gssg, monocyte chemoattractant protein-1 (mcp-1), 8-isoprostane being most important biomarkers. Conclusions: Comorbidities affect the hypothesized biomarkers as diabetes progresses. Mitochondrial oxidative stress indicators, coagulation, and inflammatory markers help assess diabetes disease development and provide appropriate medications. Future studies will examine longitudinal biomarker evolution.
Sex differences in histopathological markers of cerebral amyloid angiopathy and related hemorrhage
Authors: Koemans Emma A , Perosa Valentina , Freeze Whitney M , Lee Hang , Kozberg Mariel G , Coughlan Gillian T , Buckley Rachel F , Wermer Marieke JH , Greenberg Steven M , van Veluw Susanne J 
Published: May 2024

Background: Men with cerebral amyloid angiopathy (CAA) may have an earlier onset of intracerebral hemorrhage and a more hemorrhagic disease course compared to women. In this cohort study, we investigated sex differences in histopathological markers associated with amyloid-β burden and hemorrhage in cognitively impaired individuals and patients with CAA, using neuropathological data from two autopsy databases. Methods: First, we investigated presence of parenchymal (Thal score) and vascular amyloid-β (CAA severity score) in cognitively impaired individuals from the National Alzheimer’s Coordinating Center (NACC) neuropathology database. Next, we examined sex differences in hemorrhagic ex vivo magnetic resonance imaging (MRI) markers and local cortical iron burden and the interaction of sex on factors associated with cortical iron burden (CAA percentage area and vessel remodeling) in patients with pathologically confirmed clinical CAA from the Massachusetts General Hospital (MGH) CAA neuropathology database. Results: In 6120 individuals from the NACC database (45% women, mean age 80 years), the presence of parenchymal amyloid-β (odds ratio (OR) (95% confidence interval (CI)) =0.68 (0.53–0.88)) but not vascular amyloid-β was less in men compared to women. In 19 patients with definite CAA from the MGH CAA database (35% women, mean age 75 years), a lower microbleed count (p < 0.001) but a higher proportion of cortical superficial siderosis and a higher local cortical iron burden was found in men (p < 0.001) compared to women. CAA percentage area was comparable in men and women (p = 0.732). Exploratory analyses demonstrated a possible stronger negative relation between cortical CAA percentage area and cortical iron density in men compared to women (p = 0.03). Conclusion: Previously observed sex differences in hemorrhage onset and progression in CAA patients are likely not due to differences in global CAA severity between men and women. Other factors, such as vascular remodeling, may contribute, but future studies are necessary to replicate our findings in larger data sets and to further investigate the underlying mechanisms behind these complex sex differences.
Artificial Intelligence Language Models Are Useful Tools for Patients Undergoing Total Ankle Replacement
Authors: Samsonov Alan P. , Habibi Akram , Butler James J. , Walls Raymond J. , Kennedy John G. 
Published: May 2024

Background Artificial intelligence (AI) large language models (LLMs), such as Chat Generative Pre-trained Transformer (ChatGPT), have gained traction as both augmentative tools in patient care but also as powerful synthesizing machines. The use of ChatGPT in orthopaedic foot and ankle surgery, particularly as an informative resource for patients, has not been described to date. The purpose of this study was to assess the quality of information provided by ChatGPT in response to commonly asked questions about total ankle replacement (TAR). Methods ChatGPT was asked 10 frequently asked questions about TAR in a conversational thread. Responses were recorded without follow-up, and subsequently graded A, B, C, or F, corresponding with “excellent response,” “adequate response needing mild clarification,” “inadequate response needing moderate clarification,” and “poor response needing severe clarification.” Results Of the 10 responses, 2 were grade “A,” 6 were grade “B,” 2 were grade “C,” and none were grade “F.” Overall, the LLM provided good-quality responses to the posed prompts. Conclusion. Overall, the provided responses were understandable and representative of the current literature surrounding TAR. This study highlights the potential role LLMs in augmenting patient understanding of foot and ankle operative procedures. Levels of Evidence: IV.
Maternal satisfaction on delivery service and associated factors among mothers delivered at Arba Minch town governmental health facilities, South Ethiopia: A cross-sectional study
Authors: Ezo Elias , Getachew Hana , Degefu Sindu , Ashager Kidist 
Published: May 2024

Objective: To assess maternal satisfaction with delivery service and associated factors among mothers delivered at Arba Minch town governmental health facilities, South Ethiopia, 2022. Methods: A facility-based cross-sectional design study was conducted from 1 April to 30 June 2022. The total sample size was 320. A systematic random sampling technique was used to select mothers. Data were entered using Epi-data Version 3.1 and exported to SPSS Version 25 for analysis. Multicollinearity was considered using a variance inflation factor. The goodness of fit test was done using the Hosmer–Lemeshow model. Binary logistic regression was done, and variables with a p-value of <0.25 in the bivariable analysis were taken into the multivariable analysis. Statistically significant was declared at a p-value of <0.05 with an adjusted odds ratio and 95% confidence interval. Result: The maternal satisfaction with delivery service was 75.0% (95% CI: 70.3%–79.4%). Being urban residence (AOR: 4.15, 95% CI: 1.87–9.19), absence of anemia during pregnancy (AOR: 2.38, 95% CI: 1.07–5.29), absence of antepartum hemorrhage (AOR: 2.96, 95% CI: 1.35–6.50), induction to onset labor (AOR: 0.08, 95% CI: 0.02–0.39), female sex of the newborn (AOR: 0.33, 95% CI: 0.15–0.72), absence of fetal distress during labor (AOR: 5.01, 95% CI: 1.69–14.86), absence of intrauterine meconium release (AOR: 2.77, 95% CI: 1.02–7.63), and presence of privacy measures during examination (AOR: 3.11, 95% CI: 1.37–7.04) were associated with maternal satisfaction. Conclusion and recommendation: About 8 in 10 mothers are satisfied with the delivery service. Residence, anemia during pregnancy, antepartum hemorrhage, the onset of labor, sex of the newborn, fetal distress during labor, intrauterine meconium release, and privacy measures during examination are associated with maternal satisfaction with delivery services. Therefore, preventing anemia during pregnancy and antepartum hemorrhage, minimizing induction of labor, preventing fetal distress and intrauterine meconium release during labor, and taking privacy measures during examination might enhance maternal satisfaction with delivery services.
How Does Financial Flexibility Strategy Impact on Risk Management Effectiveness?
Authors: Nguyen Quang Khai 
Published: May 2024

In the context of emerging countries trying to attract foreign investors, building governance strategies and risk management of firms is an increasing concern. This study investigates the impact of financial flexibility strategies on the risk management effectiveness of firms and mechanism of these impacts by focusing on Vietnamese listed firms by applying the fixed effect and system GMM methods on a sample of 635 Vietnamese listed firms during the 2010 to 2021 period to derive empirical models under the high risk-high return approach. We also applied robustness tests to ensure that the results are reliable. We also investigate the level of risk management effectiveness among these firms during the 2010 to 2021 period. We found that financial flexibility strategies negatively impact risk management effectiveness of firms through reducing both firm risk and firm performance. Furthermore, we found that the degree of risk management effectiveness differs between low- and high-risk firms in Vietnam, with low-risk firms displaying more effective risk management compared to high-risk firms. Our research shows that financial flexibility strategies are not conducive to risk management effectiveness; however, firms can control the impact of flexibility strategies on risk management by controlling firm performance and risk. JEL Classification: G30, G32, G39
The association between alcohol consumption and pulmonary function: a scoping review
Authors: Nielsen Line Bjerrehave , Johansen Maria Oxbøl , Riddersholm Signe Juul , Weinreich Ulla Møller 
Published: May 2024

Introduction:The health effects of alcohol are well established but the influence on pulmonary function remains debated. Studies indicate that small amounts of alcohol are beneficial and heavy consumption is harmful, suggesting a U-shaped association. Our objective is to determine whether there is an association between alcohol intake and changes in pulmonary function parameters, exploring the potential protective effect of moderate alcohol consumption and the harm caused by heavy drinking.Methods:A comprehensive search from PubMed, Embase, Cochrane and CINAHL was carried out, and studies were evaluated using the JBI methodological framework for scoping reviews. Two independent reviewers conducted parallel screening and data extraction. A data extraction form was utilised to organise key themes, with qualitative analysis and visual representation of the results.Results:Among 4427 screened abstracts, 179 underwent full-text review, resulting in 30 eligible studies. Of these, 10 showed a negative effect, nine reported no impact, nine exhibited a positive effect and two indicated a nonlinear U-shaped association between alcohol consumption and pulmonary function parameters.Conclusion:While the U-shaped curve hypothesis remains unconfirmed by the current literature, there are notable associations. Heavy alcohol consumption appears to negatively affect pulmonary function, while low to moderate intake shows a positive influence in included studies. However, the diversity in study quality, the nonstandardised alcohol intake quantification and the confounding role of smoking challenge definitive conclusions. The need for consistent, long-term international studies is evident to further explore this relationship while addressing the complex interplay between alcohol and smoking.
Impact of silver nanoparticles on secondary metabolite composition and toxicity in anise (Pimpinella anisum L.) callus culture
Authors: Ulusoy Esma , Bozkurt Aysenur , Durmaz Sumeyye , Servi Huseyin , Vardar Filiz , Erisen Semiha 
Published: May 2024

Abstract
Background
There are numerous challenges associated with producing desired amounts of secondary metabolites (SMs), which are mostly unique and cannot be chemically synthesized. Many studies indicate that nanoparticles (NPs) can boost the production of SMs. Still, the precise manner in which NPs induce metabolic changes remains unidentified. This study examines the influence of eco-friendly silver NPs (AgNPs) on the chemical makeup and toxicity of Pimpinella anisum L. (anise).

Results
AgNPs were introduced into anise callus cultures at different concentrations (0, 1.0, 5.0, 10, and 20 mg/L). The induced oxidative stress was tracked over intervals of 7, 14, 28, and 35 days. Chemical composition evaluations were carried out on the 35th day. Within the first 14 days, plant stress was evident, though the plant adapted to the stress later on. Notably, the plant showed high tolerance at 1 mg/L and 5 mg/L concentrations despite increased toxicity levels. However, relatively high toxicity levels were identified at 10 and 20 mg/L. The AgNP-induced stress significantly impacted anise SMs, particularly affecting fatty acid content. In the 10 and 20 mg/L AgNP groups, essential metabolites, including palmitic and linoleic acid, showed a significant increase. Polyunsaturated (omega) and monounsaturated fatty acids, vital for the food and pharmaceutical industries, saw substantial growth in the 1 and 5 mg/L AgNP groups. For the first time, vanillyl alcohol and 4-Hydroxybenzoic acid were detected along with various phenolic compounds, such as t-anethole, Salicylic acid, and Thiamazole.

Conclusion
AgNPs can function as an elicitor to efficiently generate essential SMs such as omegas and phenolic compounds in anise callus culture. This study explores the application of AgNPs as plant elicitors in anise SM production, offering invaluable insight into potential uses.
Sexually transmitted infections, the epidemic that persists after the COVID-19 pandemic: an analysis of the primary care electronic health records covering about 5 million people in Catalonia
Authors: Guiriguet Carolina , Alberny Mireia , Mora Núria , Rebagliato Oriol , Roca Carme , Fina Francesc , Fàbregas Mireia , Benítez Mència , de la Poza Mariam , Medina Manuel , Flayeh Souhel , Pedrazas David , Sabatés Montserrat , Coma Ermengol 
Published: May 2024

Abstract
Background
The aim of our study is to analyse the trends in the diagnosis of sexually transmitted infections (STIs) during the COVID-19 pandemic.

Methods
We conducted an observational retrospective population-based study using data from primary care electronic health records spanning from January 2016 to December 2022 (involving 5.1 million people older than 14 years). We described the daily number of new STI diagnoses from 2016 to 2022; as well as the monthly accumulation of new STI diagnoses for each year. We compared the monthly averages of new diagnoses in 2019, 2020, 2021 and 2022 using the T-test. Finally, we performed a segmented regression analysis of the daily number of STI diagnoses.

Results
We analysed 200,676 new STI diagnoses. The number of diagnoses abruptly decreased coinciding with the lockdown. Overall in 2020, we observed a reduction of 15%, with higher reductions for specific STIs such as gonorrhoea (-21%), chlamydia (-24%), and HIV (-31%) compared to 2019. Following this drastic drop, which was temporarily associated with the lockdown, we observed a rapid rebound. In 2021, the number of STI diagnoses was similar to that of 2019. Notably, we found a considerable increase in 2022, particularly for non-specific STI, which lack laboratory confirmation (67% increase). HIV was the only STI with a reduction of up to -38% in diagnoses at the end of 2022 compared to 2019.

Conclusions
After a significant reduction in 2020, the number of STIs recorded in primary care rapidly rebounded, and the current trend is similar to that of 2019, except for HIV. These findings underscore the dynamic impact of the COVID-19 pandemic on STI diagnoses and highlight the importance of ongoing monitoring and public health interventions in the post-pandemic period.
Progressive multifocal leukoencephalopathy in a patient with B-cell chronic lymphocytic leukemia after COVID-19 vaccination, complicated with COVID-19 and mucormycosis: a case report
Authors: Amirifard Hamed , Shahbazi Mojtaba , Farahmand Ghasem , Ranjbar Zahra , Kaeedi Maryam , Heydari Havadaragh Sanaz 
Published: May 2024

Abstract
Background
Progressive multifocal leukoencephalopathy (PML) is a rare and fatal opportunistic viral demyelinating infectious disease of the central nervous system (CNS). There are various clinical presenting symptoms for the disease.

Case presentation
This paper presents a clinical case of PML in a patient with B-Chronic lymphocytic leukemia (B-CLL), previously treated with Chlorambucil, later complicated later with COVID-19 and mucormycosis.

Conclusion
PML can develop in the setting of cellular immune dysfunction. Late diagnosis of this disease based on nonspecific symptoms is common, therefore when we face a neurological complication in a CLL or immunocompromised patient, we should consider PML infection. A remarkable feature of this case is the possible triggering effect of COVID-19 vaccination for emergence of PML as the disease can be asymptomatic or sub-clinical before diagnosis.