bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prefabricated Fibula Flap vs Bone-Driven and Delayed Implant Installation for Jaw Reconstruction
Authors: Tabet Paul , Bellavance Samuel , Harris Jeffrey R. , Ansari Khalid , Osswald Martin , Nayar Suresh , Seikaly Hadi 
Published: May 2024

ImportanceRestoration of dental occlusion and oral rehabilitation is the ultimate goal of functional jaw reconstruction.ObjectiveTo evaluate the prefabricated fibula flap (PFF) technique in occlusion-driven jaw reconstruction for benign or previously treated malignant disease.Design, Setting, and ParticipantsThis cohort study was conducted from January 2000 to December 2019 at the University of Alberta Hospital and Institute of Reconstructive Sciences in Medicine in Edmonton, Alberta, Canada, among patients who underwent PFF or bone-driven and delayed osseointegrated implant installation (BDD). Patients were followed up for a minimum of 1 year after occlusal rehabilitation. Data were analyzed from July 2021 to June 2022.ExposuresPatients underwent BDD or PFF, which consists of osseointegrated dental implant installation and skin grafting of the fibular bone 3 to 6 months before jaw tumor resection or defect reconstruction. The implant osseointegration is completed at the time of jaw reconstruction, allowing for full reconstruction, loading, and restoration of the dental occlusion in the immediate postoperative period.Main outcomes and MeasureSafety, effectiveness, accuracy, timeliness of occlusal reconstruction, and aesthetic appeal were compared between PFF and BDD. Groups were compared for the following variables: postoperative complications, number of bony segments used, number of procedures needed, total operative time, time to occlusal rehabilitation, and number of implants installed, exposed, lost, and used (ie, exposed implants – lost implants). Aesthetic appeal was assessed using standardized full-face and profile digital photographs taken before and 6 to 12 months after the operation and analyzed by 3 naive raters.ResultsAmong 9 patients receiving PFF (mean [SD] age, 43.3 [13.0] years; 7 men [77.8%]) and 12 patients receiving BDD (mean [SD] age, 41.9 [18.0] years; 8 men [66.7%]), the overall complication rate was similar (4 patients [44.4%] vs 3 patients [25.0%], respectively; relative risk, 1.78 [95% CI, 0.52 to 6.04]). The number of patients with implant loss was similar between PFF and BDD groups (0 patients vs 3 patients [25.0%], respectively; difference, −25.0 percentage points [95% CI, −48.4 to 9.7 percentage points]). PFF had a clinically meaningful faster mean (SD) occlusal rehabilitation compared with BDD (12.1 [1.9] months vs 60.4 [23.1] months; difference, −48.3 months [95% CI, −64.5 to −32.0 months]). The mean (SD) difference in preoperative to postoperative aesthetic score was similar between PFF and BDD groups (−0.8 [1.5] vs −0.2 [0.8]; difference, −0.6 [95% CI, −1.6 to 0.4]).Conclusions and RelevanceThis study found that PFF compared with BDD was a safe, effective, and aesthetic reconstructive option for patients with benign or previously treated jaw malignant tumors. This technique may provide rapid occlusal reconstruction and oral rehabilitation.
Feasibility of patient‐specific quality assurance (PSQA) for real‐time robotic stereotactic body radiotherapy (SBRT) based on tumor motion traces
Authors: Xu Qianyi , Fan Jiajin , Vinogradskiy Yevgeniy , Chawla Ashish K. , Kubicek Gregory , Yang Haihua , Huynh Kiet , LaCouture Tamara , Grimm Jimm , Nie Wei 
Published: May 2024

AbstractPurposeTo design a patient specific quality assurance (PSQA) process for the CyberKnife Synchrony system and quantify its dosimetric accuracy using a motion platform driven by patient tumor traces with rotation.MethodsThe CyberKnife Synchrony system was evaluated using a motion platform (MODUSQA) and a SRS MapCHECK phantom. The platform was programed to move in the superior‐inferior (SI) direction based on tumor traces. The detector array housed by the StereoPhan was placed on the platform. Extra rotational angles in pitch (head down, 4.0° ± 0.15° or 1.2° ± 0.1°) were added to the moving phantom to examine robot capability of angle correction during delivery. A total of 15 Synchrony patients were performed SBRT PSQA on the moving phantom. All the results were benchmarked by the PSQA results based on static phantom.ResultsFor smaller pitch angles, the mean gamma passing rates were 99.75% ± 0.87%, 98.63% ± 2.05%, and 93.11% ± 5.52%, for 3%/1 mm, 2%/1 mm, and 1%/1 mm, respectively. Large discrepancy in the passing rates was observed for different pitch angles due to limited angle correction by the robot. For larger pitch angles, the corresponding mean passing rates were dropped to 93.00% ± 10.91%, 88.05% ± 14.93%, and 80.38% ± 17.40%. When comparing with the static phantom, no significant statistic difference was observed for smaller pitch angles (p = 0.1 for 3%/1 mm), whereas a larger statistic difference was observed for larger pitch angles (p < 0.02 for all criteria). All the gamma passing rates were improved, if applying shift and rotation correction.ConclusionsThe significance of this work is that it is the first study to benchmark PSQA for the CyberKnife Synchrony system using realistically moving phantoms with rotation. With reasonable delivery time, we found it may be feasible to perform PSQA for Synchrony patients with a realistic breathing pattern.
Calculation method for novel upright CT scanner isodose curves
Authors: Kissick Michael W. , Panaino Costanza , Criscuolo Anthony , Hayes John , Hoffman Carson , Mackie Rockwell , Schreuder Andries N. 
Published: May 2024

AbstractPurposeA computational method based on Monte‐Carlo calculations is presented and used to calculate isodose curves for a new upright and tilting CT scanner useful for radiation protection purposes.MethodsThe TOPAS code platform with imported CAD files for key components was used to construct a calculation space for the scanner. A sphere of water acts as the patient would by creating scatter out of the bore. Maximum intensity dose maps are calculated for various possible tilt angles to make sure radiation protection for site planning uses the maximum possible dose everywhere.ResultsThe resulting maximum intensity isodose lines are more rounded than ones for just a single tilt angle and so closer to isotropic. These maximum intensity curves are closer to the isotropic assumption used in CTDI or DLP based methods of site planning and radiation protection. The isodose lines are similar to those of a standard CT scanner, just tilted upwards. There is more metal above the beam that lessens the dose above versus below isocenter.ConclusionAside from the orientation, this upright scanner is very similar to a typical CT scanner, and nothing different for shielding needs to be done for this new upright tilting CT scanner, because an isotropic scatter source is often assumed for any CT scanner.
Development of a phantom for assessing the precision of setup in skin mark‐less surface‐guided radiotherapy
Authors: Saito Masahide , Ueda Koji , Nemoto Hikaru , Onishi Yoshiko , Suzuki Hidekazu , Suzuki Toshihiro , Sano Naoki , Komiyama Takafumi , Marino Kan , Onishi Hiroshi 
Published: May 2024

AbstractBackgroundSurface‐guided radiotherapy (SGRT) is adopted by several institutions; however, reports on the phantoms used to assess the precision of the SGRT setup are limited.PurposeThe purpose of this study was to develop a phantom to verify the accuracy of the irradiation position during skin mark‐less SGRT.MethodsAn acrylonitrile butadiene styrene (ABS) plastic cube phantom with a diameter of 150 mm on each side containing a dummy target of 15 mm and two types of body surface‐shaped phantoms (breast/face shape) that could be attached to the cube phantom were fabricated. Films can be inserted on four sides of the cubic phantom (left, right, anterior and posterior), and the center of radiation can be calculated by irradiating the dummy target with orthogonal MV beams. Three types of SGRT using a VOXELAN‐HEV600M (Electronics Research&Development Corporation, Okayama, Japan) were evaluated using this phantom: (i) SGRTCT—a SGRT set‐up based solely on a computed tomography (CT)‐reference image. (ii) SGRTCT + CBCT—a method where cone beam computed tomography (CBCT) matching was performed after SGRTCT. (iii) SGRTScan—a resetup technique using a scan reference image obtained after completing the (ii) step.ResultsBoth the breast and face phantoms were recognized in the SGRT system without problems. SGRTScan ensure precision within 1 mm/1° for breast and face verification, respectively. All SGRT methods showed comparable rotational accuracies with no significant disparities.ConclusionsThe developed phantom was useful for verifying the accuracy of skin mark‐less SGRT position matching. The SGRTScan demonstrated the feasibility of achieving skin‐mark less SGRT with high accuracy, with deviations of less than 1 mm. Additional research is necessary to evaluate the suitability of the developed phantoms for use in various facilities and systems. This phantom could be used for postal surveys in the future.
Advances in Bioadhesive Hydrogels for Musculoskeletal Tissue Application
Authors: Zhang Fang‐Xue , Chien Meng‐Han , Fan Qing‐rui , Jiang Dong 
Published: May 2024

AbstractThe musculoskeletal system, which is responsible for weight‐bearing, movement, and organ protection, faces many disorders arising from injuries, diseases, and trauma that affect millions of people worldwide, resulting in a decreased quality of life and socioeconomic burden. Tissue engineering is at the forefront of current research on tissue regeneration and demonstrates great potential for musculoskeletal tissue repair. Among the numerous grafts available, adhesive hydrogels have demonstrated potential for tissue applications. Despite the surge in the development of bioadhesive hydrogel formulations in recent years, the absence of an evaluation protocol for their formulation has led to the emergence of numerous similar products that do not fully meet the clinical requirements for applicability in musculoskeletal tissue regeneration. This review aims to address this gap by first discussing the design considerations for an ideal bioadhesive hydrogel relevant to successful musculoskeletal tissue repair. By thoroughly reviewing recent research advances in bioadhesive hydrogels, with a particular focus on their applications in facilitating musculoskeletal tissue repair, improvements are proposed in the current evaluation criteria for the development of novel bioadhesive hydrogels for musculoskeletal tissue applications, and several key challenges and research directions for their implementation are summarized.
Efficient Carbon‐Based Hole‐Conductor‐Free Printable Mesoscopic Perovskite Solar Cells via a Multifunctional Fluorinated Molecule
Authors: Xiang Junwei , Cheng Yanjie , Zhang Guodong , Liu Zhiyang , Han Chuanzhou , Gao Qiaojiao , Wang Chaoyang , Xie Jiayu , Li Shiang , Zhou Zijian , Liu Jing , Lu Xinhui , Mei Anyi , Zhou Yinhua , Han Hongwei 
Published: May 2024

AbstractBenefiting from their simple and cost‐effective fabrication procedures, printable mesoscopic perovskite solar cells (p‐MPSCs) exhibit substantial potential for large‐scale production. In p‐MPSCs, the thickness of the perovskite filled in the TiO2 and ZrO2 mesoporous layers is ≈3 µm. Therefore, the perovskite crystallization process is more intricate and challenging in the mesoporous structure than the general planar thin film (0.3–0.5 µm). In this work, a multifunctional fluorinated molecule is applied to work as an additive to improve the perovskite crystallization, enhance the device efficiency, and elevate the operational stability. This additive forms robust coordination between its carbonyl groups and uncoordinated Pb2+, thereby effectively passivating defects. The hydrophobic properties of the fluorinated molecule contribute to the device's water‐resistant capability and long‐term operational stability. With these synergistic effects, the power conversion efficiency (PCE) of small‐area cells (0.1 cm2) reaches 20.15% under 1 sun illumination. Large‐area modules (56.4 cm2) are fabricated and exhibit a PCE of 15.41%.
Tensile Control of Vibrational Strong Light‐Matter Coupling with Flexible Polyester Films
Authors: Akinoglu Goekalp Engin , Quan Dali , Rokhsat Eliza , Hutchison James Andell 
Published: May 2024

AbstractPolaritons are generated by strong interaction between photons and matter, with the hybridization fundamentally changing the energy landscape of the system. Future exploitation of polaritons will benefit from implementing low‐cost, flexible, and easily tuneable configurations, as electronics have before. Here, coherent coupling of the carbonyl stretch vibrations of polyester (poly(ethylene terephthalate), PET) films to the optical modes of a Fabry–Perot (FP) cavity is presented, in which the FP cavity is directly formed on flexible, free‐standing, and commercially available PET films. For 2‐µm thick PET films, the carbonyl stretch vibration of the PET overlaps with the half‐wavelength FP cavity mode, leading to the coupling of the two modes, a Rabi splitting above 160 cm−1, and associated anticrossing in angular dispersion measurements. The study demonstrates dynamic control of light‐matter interaction strength by modulating film thickness under tension, finding that a 25% tensile stretch can tune the light‐matter interaction from 20:80 mixing to near‐perfect 50:50 hybridization at normal incidence. These findings are discussed in the context of future foldable/twistable/wearable polaritonic devices.
Critical Factors Contributing to the Thermal Runaway of Thiophosphate Solid Electrolytes for All‐Solid‐State Batteries
Authors: Kim Taehun , Chang Hongjun , Song Gawon , Lee Suyeon , Kim Kanghyeon , Lee Seonghyun , Moon Janghyuk , Lee Kyu Tae 
Published: May 2024

AbstractAlthough all‐solid‐state batteries are suggested as a means to tackle the safety concerns associated with current Li‐ion batteries, there is presently a lack of comprehensive understanding regarding their thermal safety. In this context, critical factors contributing to the thermal runaway of thiophosphate solid electrolytes with charged Li1‐xNi0.8Co0.1Mn0.1O2 (NCM) under thermal and mechanical abuse conditions are demonstrated, considering parameters such as heating rate under thermal abuse conditions and the hybridization of S atom in structure. In particular, the thermal behavior of various solid electrolytes, including thiophosphates, thioantimonates, and halides, is investigated to clarify critical elements in Li6PS5Cl (LPSCl) contributing to its thermal instability when combined with charged NCM. Various ex situ analyses, along with density functional theory calculations, reveal a correlation between the hybridization of S atoms and the thermal instability of solid electrolytes, suggesting that sulfur acts as a key element triggering the thermal runaway of sulfide‐based solid electrolytes.
Water‐Mediated On‐Demand Detachable Solid‐State Adhesive of Porous Hydroxyapatite for Internal Organ Retractions
Authors: Okada Masahiro , Xie Shi Chao , Kobayashi Yusuke , Yanagimoto Hiroaki , Tsugawa Daisuke , Tanaka Masaru , Nakano Takayoshi , Fukumoto Takumi , Matsumoto Takuya 
Published: May 2024

AbstractNovel adhesives for biological tissues offer an advanced surgical approach. Here, the authors report the development and application of solid‐state adhesives consisting of porous hydroxyapatite (HAp) biocompatible ceramics as novel internal organ retractors. The operational principles of the porous solid‐state adhesives are experimentally established in terms of water migration from biological soft tissues into the pores of the adhesives, and their performance is evaluated on several soft tissues with different hydration states. As an example of practical medical utility, HAp adhesive devices demonstrate the holding ability of porcine livers and on‐demand detachability in vivo, showing great potential as internal organ retractors in laparoscopic surgery.
Water‐Responsive Self‐Contractive Silk‐Based Skin Anti‐Aging Tensioners with Customizable Biofunctions
Authors: Xie Yating , Geng Lele , Ni Siyuan , Ni Wei , He Ruizhe , Liu Tiantian , Zhang Gai , Tao Tiger H. , Liu Keyin , Peng Yinbo 
Published: May 2024

AbstractSkin anti‐aging treatments have become increasingly popular. Currently, the prevalent treatment method involves implanting skin tension regulation threads (skin lifting threads) under the skin, and radiofrequency treatments. In this study, inspired by the natural supercontraction of spider silk, the molecular structure of silk fibroin fibers is modulated into an oriented configuration. This modification endows silk proteins with water‐responsive self‐contraction capabilities, leading to the development of innovative self‐contracting silk‐based skin tensioners (SSSTs). To align with clinical requirements, skin tension regulation materials are functionalized by testing for their self‐contraction, near‐infrared laser heating function, and bacteriostatic properties. The SSSTs exhibited remarkable self‐contraction properties, drug‐loading and sustained‐release capabilities, notable antibacterial effects, controllable degradation, and good biocompatibility. Moreover, the near‐infrared light heating function effectively increased subcutaneous temperature, demonstrating its potential for enhancing and prolonging skin lifting effects. Therefore, SSSTs can be applied for skin tension regulation to improve and delay skin aging. The results may pave the way for novel strategies in skin rejuvenation, with broad implications for the field of skin anti‐aging.
Single‐Step Control of Liquid–Liquid Crystalline Phase Separation by Depletion Gradients
Authors: Lin Dongdong , Bagnani Massimo , Almohammadi Hamed , Yuan Ye , Zhao Yufen , Mezzenga Raffaele 
Published: May 2024

AbstractFine‐tuning nucleation and growth of colloidal liquid crystalline (LC) droplets, also known as tactoids, is highly desirable in both fundamental science and technological applications. However, the tactoid structure results from the trade‐off between thermodynamics and nonequilibrium kinetics effects, and controlling liquid–liquid crystalline phase separation (LLCPS) in these systems is still a work in progress. Here, a single‐step strategy is introduced to obtain a rich palette of morphologies for tactoids formed via nucleation and growth within an initially isotropic phase exposed to a gradient of depletants. The simultaneous appearance is shown of rich LC structures along the depleting potential gradient, where the position of each LC structure is correlated with the magnitude of the depleting potential. Changing the size (nanoparticles) or the nature (polymers) of the depleting agent provides additional, precise control over the resulting LC structures through a size‐selective mechanism, where the depletant may be found both within and outside the LC droplets. The use of depletion gradients from depletants of varying sizes and nature offers a powerful toolbox for manipulation, templating, imaging, and understanding heterogeneous colloidal LC structures.
Side Reactions/Changes in Lithium‐Ion Batteries: Mechanisms and Strategies for Creating Safer and Better Batteries
Authors: Du Hao , Wang Yadong , Kang Yuqiong , Zhao Yun , Tian Yao , Wang Xianshu , Tan Yihong , Liang Zheng , Wozny John , Li Tao , Ren Dongsheng , Wang Li , He Xiangming , Xiao Peitao , Mao Eryang , Tavajohi Naser , Kang Feiyu , Li Baohua 
Published: May 2024

AbstractLithium‐ion batteries (LIBs), in which lithium ions function as charge carriers, are considered the most competitive energy storage devices due to their high energy and power density. However, battery materials, especially with high capacity undergo side reactions and changes that result in capacity decay and safety issues. A deep understanding of the reactions that cause changes in the battery's internal components and the mechanisms of those reactions is needed to build safer and better batteries. This review focuses on the processes of battery failures, with voltage and temperature as the underlying factors. Voltage‐induced failures result from anode interfacial reactions, current collector corrosion, cathode interfacial reactions, overcharge, and over‐discharge, while temperature‐induced failure mechanisms include SEI decomposition, separator damage, and interfacial reactions between electrodes and electrolytes. The review also presents protective strategies for controlling these reactions. As a result, the reader is offered a comprehensive overview of the safety features and failure mechanisms of various LIB components.
Stable Oxyhalide‐Nitride Fast Ionic Conductors for All‐Solid‐State Li Metal Batteries
Authors: Ma Baochen , Li Ruhong , Zhu Haotian , Zhou Tao , Lv Ling , Zhang Haikuo , Zhang Shuoqing , Chen Long , Wang Jinze , Xiao Xuezhang , Deng Tao , Chen Lixin , Wang Chunsheng , Fan Xiulin 
Published: May 2024

AbstractRechargeable all‐solid‐state lithium metal batteries (ASSLMBs) utilizing inorganic solid‐state electrolytes (SSEs) are promising for electric vehicles and large‐scale grid energy storage. However, the Li dendrite growth in SSEs still constrains the practical utility of ASSLMBs. To achieve a high dendrite‐suppression capability, SSEs must be chemically stable with Li, possess fast Li transfer kinetics, and exhibit high interface energy. Herein, a class of low‐cost, eco‐friendly, and sustainable oxyhalide‐nitride solid electrolytes (ONSEs), denoted as LixNyIz‐qLiOH (where x = 3y + z, 0 ≤ q ≤ 0.75), is designed to fulfill all the requirements. As‐prepared ONSEs demonstrate chemically stable against Li and high interface energy (>43.08 meV Å−2), effectively restraining Li dendrite growth and the self‐degradation at electrode interfaces. Furthermore, improved thermodynamic oxidation stability of ONSEs (>3 V vs Li+/Li, 0.45 V for pure Li3N), arising from the increased ionicity of Li─N bonds, contributes to the stability in ASSLMBs. As a proof‐of‐concept, the optimized ONSEs possess high ionic conductivity of 0.52 mS cm−1 and achieve long‐term cycling of Li||Li symmetric cell for over 500 h. When coupled with the Li3InCl6 SSE for high‐voltage cathodes, the bilayer oxyhalide‐nitride/Li3InCl6 electrolyte imparts 90% capacity retention over 500 cycles for Li||1 mAh cm−2 LiCoO2 cells.
Constructing High‐Active Surface of Plasmonic Tungsten Oxide for Photocatalytic Alcohol Dehydration
Authors: Tian Dehua , Liu Xiaolei , Li Juan , Wang Zeyan , Cai Xiaoyan , Chen Jiangyi , Jin Hao , Li Baojun , Lou Zaizhu 
Published: May 2024

AbstractPlasmonic semiconductors with broad spectral response hold significant promise for sustainable solar energy utilization. However, the surface inertness limits the photocatalytic activity. Herein, a novel approach is proposed to improve the body crystallinity and increase the surface oxygen vacancies of plasmonic tungsten oxide by the combination of hydrochloric acid (HCl) regulation and light irradiation, which can promote the adsorption of tert‐butyl alcohol (TBA) on plasmonic tungsten oxide and overcome the hindrance of the surface depletion layer in photocatalytic alcohol dehydration. Additionally, this process can concentrate electrons for strong plasmonic electron oscillation on the near surface, facilitating rapid electron transfer within the adsorbed TBA molecules for C‐O bond cleavage. As a result, the activation barrier for TBA dehydration is significantly reduced by 93% to 6.0 kJ mol−1, much lower than that of thermocatalysis (91 kJ mol−1). Therefore, an optimal isobutylene generation rate of 1.8 mol g−1 h−1 (selectivity of 99.9%) is achieved. A small flow reaction system is further constructed, which shows an isobutylene generation rate of 12 mmol h−1 under natural sunlight irradiation. This work highlights the potential of plasmonic semiconductors for efficient photocatalytic alcohol dehydration, thereby promoting the sustainable utilization of solar energy.