bluuebunny/crossref_metadata_2025_split huggingface dataset:
Femmes et richesse : au-delà du PIB
Authors: Jany-Catrice Florence , Méda Dominique 
Published: November 2011

Résumé La mesure actuellement la plus utilisée pour recenser la richesse d’un pays est le Produit intérieur brut, qui représente la valeur monétaire des biens et services fabriqués une année donnée. Cet indicateur a été inventé au sortir de la Seconde Guerre mondiale. Comme tous les indicateurs il est issu de « conventions », parmi lesquelles celle de ne pas considérer comme faisant partie de la richesse nationale les activités réalisées au sein du foyer, qui ont très longtemps été prises en charge par les seules femmes et dont la répartition reste encore aujourd’hui très déséquilibrée entre les femmes et les hommes. L’article vise dans un premier temps à revenir sur les raisons – implicites ou explicites – de cette exclusion. Il présente ensuite une des manières de faire justice à un certain nombre de revendications féministes qui considèrent légitime de prendre au moins la mesure de la contribution de la production domestique à la richesse nationale en réalisant une estimation monétaire de celle-ci. Après avoir envisagé les différentes méthodes d’estimation, jusqu’à la plus récente, proposée par la Commission Stiglitz et l’ ocde , ainsi que les avantages et inconvénients de celles-ci, nous analysons dans une dernière partie une autre manière de dépasser les limites intrinsèques au pib : le développement de nouveaux indicateurs plus axés sur la santé sociale, en envisageant, de manière exploratoire, les modalités d’une meilleure prise en compte des inégalités entre femmes et hommes.
Pathogenic and Protective Functions of TNF in Neuroinflammation Are Defined by Its Expression in T Lymphocytes and Myeloid Cells
Authors: Kruglov Andrey A. , Lampropoulou Vicky , Fillatreau Simon , Nedospasov Sergei A. 
Published: November 2011

Abstract
TNF displays pathogenic activities in many autoimmune disorders. However, anti-TNF therapy in multiple sclerosis patients failed because of poorly understood reasons. We used a panel of gene-targeted mice that allowed cell-type specific ablation of TNF to uncover pathogenic and protective contributions of this cytokine during autoimmune disease of the CNS. T cells and myeloid cells were found to be critical cellular sources of TNF during experimental autoimmune encephalomyelitis (EAE). TNF produced by myeloid cells accelerated the onset of disease by regulation of chemokine expression in the CNS, driving the recruitment of inflammatory cells into the target organ. TNF produced by T cells exacerbated the damage to the CNS during EAE by regulating infiltration of inflammatory myeloid cells into the CNS. In secondary lymphoid organs, TNF expressed by myeloid cells and T cells acted in synergy to dampen IL-12p40 and IL-6 production by APCs, subsequently inhibiting the development of encephalitogenic T cell responses of Th1 and Th17 types. This dual role of TNF during EAE (protective in lymphoid organs and pathogenic in CNS) suggests that global TNF blockade might be inefficient in multiple sclerosis patients because augmented autoreactive T cell development in lymphoid tissues might overwhelm the beneficial effects resulting from TNF inhibition in the CNS.
Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus
Authors: Kahlenberg J. Michelle , Thacker Seth G. , Berthier Celine C. , Cohen Clemens D. , Kretzler Matthias , Kaplan Mariana J. 
Published: November 2011

Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous manifestations including severe organ damage and vascular dysfunction leading to premature atherosclerosis. IFN-α has been proposed to have an important role in the development of lupus and lupus-related cardiovascular disease, partly by repression of IL-1 pathways leading to impairments in vascular repair induced by endothelial progenitor cells (EPCs) and circulating angiogenic cells (CACs). Counterintuitively, SLE patients also display transcriptional upregulation of the IL-1β/IL-18 processing machinery, the inflammasome. To understand this dichotomy and its impact on SLE-related cardiovascular disease, we examined cultures of human and murine control or lupus EPC/CACs to determine the role of the inflammasome in endothelial differentiation. We show that caspase-1 inhibition improves dysfunctional SLE EPC/CAC differentiation into mature endothelial cells and blocks IFN-α–mediated repression of this differentiation, implicating inflammasome activation as a crucial downstream pathway leading to aberrant vasculogenesis. Furthermore, serum IL-18 levels are elevated in SLE and correlate with EPC/CAC dysfunction. Exogenous IL-18 inhibits endothelial differentiation in control EPC/CACs and neutralization of IL-18 in SLE EPC/CAC cultures restores their capacity to differentiate into mature endothelial cells, supporting a deleterious effect of IL-18 on vascular repair in vivo. Upregulation of the inflammasome machinery was operational in vivo, as evidenced by gene array analysis of lupus nephritis biopsies. Thus, the effects of IFN-α are complex and contribute to an elevated risk of cardiovascular disease by suppression of IL-1β pathways and by upregulation of the inflammasome machinery and potentiation of IL-18 activation.
Availability of Lactation Counseling Services Influences Breastfeeding among Infants Admitted to Neonatal Intensive Care Units
Authors: Castrucci Brian C. , Hoover Kathleen L. , Lim Suet , Maus Katherine C. 
Published: November 2011

Purpose. To assess the association between the presence of international board-certified lactation consultant (IBCLC) services at a delivery hospital and the breastfeeding practices of women whose infants required neonatal intensive care unit (NICU) admission. Design. Cross-sectional study using population-level data. Setting. Philadelphia, Pennsylvania. Subjects. 2132 infants admitted to the NICU. Measures. Breastfeeding at hospital discharge was measured with the question, “Is the infant being breastfed?” Delivery hospitals were dichotomized as to the presence or absence of an IBCLC on staff. Analysis. Logistic regression was used to assess the relationship between breastfeeding at discharge and the presence of an IBCLC at the delivery facility while adjusting for maternal characteristics and birth outcomes. Results. Among mothers of infants admitted to the NICU, breastfeeding rates among mothers who delivered at hospitals with an IBCLC were nearly 50% compared with 36.9% among mothers who delivered at hospitals without an IBCLC. The adjusted odds of breastfeeding initiation prior to hospital discharge were 1.34 (95% confidence interval = 1.03, 1.76) times higher for women who delivered at a facility with an IBCLC. Conclusions. To increase breastfeeding rates among the NICU population, these findings support the need for universal availability of IBCLCs at delivery facilities that have NICUs.
Use of Medicare Summary Notice Inserts to Generate Interest in the Medicare Stop Smoking Program
Authors: Maglione Margaret , Larson Carrie , Giannotti Tierney , Lapin Pauline 
Published: November 2011

Purpose. Evaluations of outreach strategies that effectively and efficiently reach the senior population often go unreported. The Medicare Stop Smoking Program (MSSP) was a seven-state demonstration project funded by the Centers for Medicare and Medicaid Services. The 1-year recruitment plan for MSSP included a multifaceted paid media campaign; however, enrollment was slower than anticipated. The purpose of this substudy was to test the effects of including envelope-sized advertisement inserts with Medicare Summary Notices (MSNs) as a supplemental recruitment strategy. Methods. Information obtained from enrollees on where they had learned about the program as well as overall enrollment rates were analyzed and compared with the time periods during which the inserts were included in MSN mailings. Results. Average call volume to the enrollment center increased by 65.7% in Alabama, the pilot state, and by more than 200% in the subsequent demonstration states. Despite the introduction of the MSN inserts late in the recruitment period, 32.2% of the 7354 total enrollees stated that they learned about the project through the inserts. Conclusions. This recruitment method is highly recommended as a cost-effective way to reach the senior population.
Attributes of Environments Supporting Walking
Authors: Moudon Anne Vernez , Lee Chanam , Cheadle Allen D. , Garvin Cheza , Johnson Donna B. , Schmid Thomas L. , Weathers Robert D. 
Published: November 2011

Purpose. This study established a framework to audit environments supporting walking in neighborhoods. Design. Cross-sectional analysis using a telephone survey and 200 objective environmental variables. Setting. Urbanized King County, WA. Subjects. 608 randomly sampled adults. Measures. Walking measures constructed from survey questions; objective environmental measures taken from parcel-level databases in Geographic Information Systems. Analysis. Multinomial models estimated the odds of people engaging in moderate walking (< 149 min/wk) and in walking sufficiently to meet recommendations for health (150+min/wk), relative to not walking; and in walking sufficiently, relative to walking moderately. A base model consisted of survey variables, and final models incorporated both survey and environmental variables. Results. Survey variables strongly associated with walking sufficiently to enhance health included household income, not having difficulty walking, using transit, perceiving social support for walking, walking outside of the neighborhood, and having a dog (p < .01). The models isolated 14 environmental variables associated with walking sufficiently (pseudo R2 up to 0.46). Measures of distance to neighborhood destinations dominated the results: shorter distances to grocery stores/markets, restaurants, and retail stores, but longer distances to offices or mixed-use buildings (p < .01 or .05). The density of the respondent's parcel was also strongly associated with walking sufficiently (p < .01). Conclusions. The study offered valid environmental measures of neighborhood walkability.
The Health Benefits of Moderate Drinking Revisited: Alcohol Use and Self-Reported Health Status
Authors: French Michael T. , Zavala Silvana K. 
Published: November 2011

Purpose. To examine the association between alcohol use and self-reported health status. In particular, we sought to determine whether moderate drinkers are more likely to self-report above-average health status compared with other current drinkers, former drinkers, and lifetime abstainers. Design. Cross-sectional survey. Setting. Continental United States. Subjects. The sample adult component of the 2002 U.S. National Health Interview Survey (n = 31,044), representative of the U.S. noninstitutionalized civilian household population. Measures. Dichotomous measure of above-average self-reported health status relative to all other health states. Several measures characterized alcohol use patterns (i.e., continuous and categorical measure of alcohol use, a proxy measure of problem drinking, former drinking, lifetime abstaining). Chronic health conditions and various demographic and lifestyle factors were included as covariates in all regression models. Results. For both men and women, current moderate drinkers had the highest odds (OR = 1.27 for men, p < .01; OR = 2.03 for women, p < .01) of reporting above-average health status compared with other current drinkers, former drinkers, and lifetime abstainers. The odds dropped to 1.12 and 1.34, respectively, when all past-year drinkers were collapsed into a single group. Conclusion. Moderate alcohol consumption was associated with the highest odds of reporting above-average health status, even after controlling for chronic health conditions and demographic and lifestyle factors associated with health.
Relationship of Stages of Change to Attendance in a Diabetes Prevention Program
Authors: Helitzer Deborah L. , Peterson Arlana Bobo , Sanders Margaret , Thompson Janice 
Published: November 2011

Purpose. To determine whether preintervention stage-of-change measures are indicative of subsequent attendance at diabetes prevention intervention sessions. Design. Cross-sectional. Setting. Local community. Subjects. Seventy-five adult American Indian women participated. Measures. Attendance, stage-of-change questions for seven diabetes prevention behaviors, and mean stage-of-change score to reflect the combined stages of change for all behaviors. Analysis. Univariate analyses for stage-of-change distribution and Fisher's exact test and prevalence ratios for the association between attendance and stage of change. Results. Participants' readiness for change at baseline was distributed across all stages of change. The most common stage was preparation. There was a significant relationship between the mean stage-of-change scores and attendance. Participants with lower mean stage-of-change scores (mean ± SE, 3.03 ± 0.13) were less likely to attend all 5 sessions than those with higher mean stage-of-change scores (mean ± SE, 3.38 ± 0.10) (p = .04). Participants in the action category (preparation, action, and maintenance stages) before the intervention were 6.7 (95% confidence interval, 1.0– 44.1; p < .01) times more likely to be high attenders than those in the preaction category (precontemplation and contemplation stages) before the intervention. Conclusions. Findings from this study suggest that stage of change may be a good predictor of attendance at diabetes prevention intervention sessions and have implications for intervention design and assessment. The mean stage-of-change score may be a more stable estimate of stage of change.
Manager Beliefs regarding Worksite Health Promotion: Findings from the Working Healthy Project 2
Authors: Linnan Laura , Weiner Bryan , Graham Amanda , Emmons Karen 
Published: November 2011

Purpose. To explore differences in manager beliefs about worksite health promotion programs (HPPs). Design. Cross-sectional written survey. Setting. Twenty-four manufacturing worksites, with 11,811 employees and 1719 eligible managers. Subjects. Sixty-six percent (1133/1719) of managers completed the survey; 1047 managers were categorized by level (169 senior, 567 middle, and 311 line supervisors). Analysis. Results are reported on overall manager beliefs (and by manager level) about importance, efficacy, barriers, and benefits of HPPs. Multilevel analysis modeled the influence of manager level, age, and experience with HPPs on beliefs about HPPs, while accounting for worksite-level effects. Results. Seventy-five percent of managers believed that offering HPPs is highly important. Eighty percent believed that HPPs improved employee health, 68% believed that they reduced health care costs, and 67% believed that they improved employee morale. Few significant differences by manager level were observed on the perceived importance of health promotion, employer responsibilities for health promotion and protection, and efficacy of health promotion strategies or perceived benefits. Senior managers (vs. line supervisors) were significantly less likely to believe that space or cost was a barrier to offering HPPs and were less likely than middle managers or line supervisors to believe that production conflicts were barriers to offering HPPs. Conclusion. Targeted interventions to address manager beliefs, including differences by age, experience, and manager level, are worth consideration when planning worksite HPPs.
Active Neighborhood Checklist: A User-Friendly and Reliable Tool for Assessing Activity Friendliness
Authors: Hoehner Christine M. , Ivy Andrae , Ramirez Laura K. Brennan , Handy Susan , Brownson Ross C. 
Published: November 2011

Purpose. To test the reliability of the Active Neighborhood Checklist (the Checklist), a user-friendly audit tool for assessing neighborhood environmental supports for physical activity. Methods. Sixty-four street segments in St. Louis and southeastern Missouri were selected among diverse areas that varied with respect to socioeconomic levels, urbanization, and land use. Fifteen public health researchers and seven community stakeholders conducted audits in April 2005 following a two-hour training session. Interrater reliability was measured for the items in each section of the Checklist (land use characteristics, sidewalks, shoulders and bike lanes, street characteristics, and quality of the environment for a pedestrian) using observed agreement and the k statistic. Results. The mean observed agreement for 57 evaluated items was 0.87 (range, 0.61–1.00). The mean k statistic was 0.68 (range, 0.21–1.00). Discussion. With minimal training of the auditors, the Checklist demonstrated strong reliability. Future studies are needed to provide information about its usability for various stakeholders and across different settings.
Performance of Imaging Devices versus Optic Disc and Fiber Layer Photography in a Clinical Practice Guideline for Glaucoma Diagnosis
Authors: Güerri Noemi , Polo Vicente , Larrosa Jose M. , Ferreras Antonio , Fuertes Isabel , Pablo Luis E. 
Published: November 2011

Purpose To compare the performance of Moorfields Regression Analysis (MRA) and optical coherence tomography (OCT) with that of photographic evaluation of the optic nerve head and retinal nerve fiber layer (RNFL) in the application of the Finnish Evidence-Based Guideline for Open-Angle Glaucoma (FEBG-OAG). Methods Patients referred for glaucoma evaluation (n=312) and subjects selected from the general population (n=41) were included in the study. All subjects underwent ophthalmic evaluation, optic nerve head stereophotography, monochromatic RNFL photography, Heidelberg retina tomography, OCT, and laser polarimetry evaluation. The subjects were classified based on stereophotographic or MRA and OCT results by applying the FEBG-OAG. Results The specificity of the FEBG-OAG for detecting normal patients (stereophotography and imaging devices) was 78% (strict criteria) and 100% (liberal criteria). Agreement between the stereophotographic evaluation and evaluation based on MRA and OCT was 70.2%. Classification of subjects with similar management advice based on these evaluations had 70.5% agreement. Central corneal thickness was a confounding factor in glaucoma diagnosis. Large optic disc sizes played a major role in misleading the diagnosis compared to small discs. Conclusions Central corneal thickness and large optic disc size are confounding factors in glaucoma diagnosis. Moorfields Regression Analysis and OCT allow for objective implementation of the FEBG-OAG compared to conventional stereophotographic evaluation of the neuroretinal structures.
Molecularly‐Engineered Lubricants: Synthesis, Activation, and Tribological Characterization of Silver Complexes as Lubricant Additives
Authors: Twist Christina P. , Seyam Afif M. , Chen Changle , Kim Myung‐Gil , Weberski Michael P. , Ren Ning , Marks Tobin J. , Chung Yip‐Wah , Wang Q. Jane 
Published: November 2011

AbstractMany machines operate in harsh environments where elevated temperatures require careful consideration of the lubricant for optimal performance. Lubricant additives can be designed to improve properties of base oil at specific temperature ranges. In the present work, two [tris(phosphino)borate]AgL (L = PEt3; NHC) complexes are synthesized and added to engine oil at various concentrations. The complexes thermolyze between 200 and 300 °C, yielding metallic Ag. A mixture of engine oil and the silver‐based nanoparticles provides fully flooded lubrication for pin‐on‐disk friction tests. A thermo‐elastohydrodynamic model for point contact is utilized to predict the pin loads at which flash temperatures between 200 and 300 °C occur, thus inducing thermal decomposition of the complexes. Results of the friction tests and wear measurements indicate a significant reduction in wear at 0.5–1.0% Ag complex weight concentrations and little change in friction. The improved wear performance is attributed to the thermolysis and deposition of the silver‐based complexes in the wear scar, as confirmed by energy‐dispersive X‐ray analysis.
Diastereo‐ and Enantioselective Synthesis of a Novel Tetracyclic Ring System via an Organocatalytic One‐Pot Reaction
Authors: Yu De‐Feng , Wang Yao , Xu Peng‐Fei 
Published: November 2011

AbstractAn efficient , asymmetric, one‐pot synthesis of a novel tetracyclic ring system incorporating both chroman and bicyclo[2.2.2]octane structural units was established through sequential reaction of nitroolefin enoates and α,β‐unsaturated ketones. Six stereogenic centers including two quaternary stereocenters were formed with excellent diastereo‐ and enantioselectivity.
Iron‐Catalyzed CH Fuctionalization of Indoles
Authors: Cai Yan , Zhu Shou‐Fei , Wang Guo‐Peng , Zhou Qi‐Lin 
Published: November 2011

AbstractAn easily available iron catalyst was developed to accomplish the CH functionalization of indoles with α‐aryl‐α‐diazoesters in high yields under mild conditions. The asymmetric CH functionalization of indoles was also realized by using iron complexes of chiral spiro bisoxazolines with up to 78% ee.
Reusable and Sustainable Nanostructured Skeleton Catalyst: Heck Reaction with Nanoporous Metallic Glass Pd (PdNPore) as a Support, Stabilizer and Ligand‐Free Catalyst
Authors: Kaneko Tetsuro , Tanaka Shinya , Asao Naoki , Yamamoto Yoshinori , Chen Mingwei , Zhang Wei , Inoue Akihisa 
Published: November 2011

AbstractNanoporous metallic glass palladium (PdNPore), which was fabricated by de‐alloying of a glassy metallic alloy Pd30Ni50P20, exhibited a remarkable catalytic activity for the Heck reaction of versatile aryl iodides and aryl bromides. Moreover, the PdNPore can be reused several times without a significant loss of catalytic activity, and the PdNPore has ahigher resistance to leaching than palladium black and palladium on carbon.
Two large‐scale surveys on community attitudes toward an opt‐out biobank
Authors: Brothers Kyle B. , Morrison Daniel R. , Clayton Ellen W. 
Published: November 2011

AbstractAlthough US research regulations allow for de‐identified biorepositories to be developed without formal informed consent from the patients whose samples are included, it is unknown whether this model will be well‐received by community members. Based on early evidence that such a biobank could be successful if patients who object have the opportunity to opt‐out, Vanderbilt University developed a biorepository named BioVU that follows this model. This study reports the findings from two large‐scale surveys among communities important to this biorepository. In the first, a population‐based phone survey of Nashville residents, we found that approval for BioVU is high (93.9%) and that this approval is similar among all population groups. A hypothetical biobank that does not obtain some form of written permission is much less well received. In the second, an online survey of Vanderbilt University faculty and staff, we found a higher level of support for BioVU (94.5%) among faculty and staff working throughout the university. In this survey, employees least likely to approve of BioVU are those employees who prefer not to receive medical care at Vanderbilt University. These surveys demonstrate the highest level of approval for a genomic biobank ever reported in the literature, even among groups traditionally cautious about such research. This high level of approval may reflect increasing comfort with genomic research over time combined with the effect that trust in a specific institution can have on approval for an operating biobank compared with approval of a hypothetical biobank. © 2011 Wiley Periodicals, Inc.