bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential Responses to Heat Stress in Normal and Dwarf Chickens: Implications for Meat Quality and Immune Function
Authors: Nawaz Ali Hassan , Wang Fujian , Jiao Zhenhai , Zhang Weilu , Zheng Jiahui , Sun Junli , Zhu Zijing , Lin Shudai , Zhang Li , Lin Junyuan 
Published: May 2024

Abstract
This study investigated the impact of heat stress (HS) on meat quality, antioxidant ability, and immunity in normal and dwarf-size chickens. A total of 144 chickens, with 72 from the normal yellow chicken (NYC) strain and 72 from the dwarf yellow chicken (DYC) strain, were equally divided into groups exposed to heat stress (35±1°C for 8 hours daily) and those kept at 28±1°C as the control group. After seven days of treatment, meat color parameters, including lightness (L*-value), redness (a*-value), and yellowness (b*-value), were assessed. Histopathological examination was conducted on spleen tissues to assess structural changes. Gene expression analysis determined the expression levels of interleukin-4 (IL-4), IL-6, and liver catalase (CAT) related to immune response and antioxidant capacity. HS significantly affected meat color parameters, with an increase in lightness (L*-value) (P<0.01) and a decrease in redness (a*-value) (P<0.01) observed in breast and thigh muscles. Furthermore, HS led to increased drip loss (P<0.05), cooking loss (P<0.05), and shear force (P<0.01) in breast muscles. Histopathological examination of spleen tissues revealed varying degrees of lymphoid depletion, necrosis, fibrosis, and inflammatory cell infiltration in response to HS. Gene expression analysis showed that HS upregulated the expression of interleukin-4 (IL-4) and IL-6 in the spleen of NYC (P<0.05) but not in DYC. Additionally, HS reduced the expression of liver catalase (CAT) in NYC (P<0.05) but had no significant effect on DYC. These findings indicate that HS adversely affects meat quality, immune response, and antioxidant capacity in broilers, with normal-sized chickens being more susceptible to these effects compared to dwarf chickens. The results provide valuable insights into the differential responses of chicken strains to HS and underscore the importance of considering genetic factors in mitigating the negative impacts of heat stress on poultry production.
American Presidential Elections 2024: The Core Point of Future Geopolitical Changes
Authors: Tabatadze Dato 
Published: May 2024

Purpose: This research is focused on the ongoing Russia – Ukraine military conflict, which has already caused some significant changes in foreign policy priorities of major players of international political system.

Objective: The objective of this study is to investigate the impact of U.S. 2024 elections to the Russia – Ukraine military conflict outcomes with the aim of analyzing different foreign policy philosophies the two potential candidates have, that can have an effect not only on current Russo-Ukrainian conflict but on the whole global geopolitical situation in the current world.

Theoretical Framework: realism as an international relations theory with the system level analysis is used to explain current global geopolitical issues.

Method: The issue of methodology is decided according to the necessities of tasks of this article and is mostly based on data analyses, comparison of similarities or differences and case study.

Results and Discussion: the current work claims that the major war on the European continent disrupts the core security arrangements which has a shattering effects of unipolar liberal order and how much will this order be changed, is mainly depended on the dedication to it by the U.S.A, European union countries and their liberal democratic allies around the globe.

Research Implications: the research findings contribute in raising awareness of the current Ukraine conflict and accumulate the type of knowledge that enriches the political science with theoretical and practical value.
PENGARUH EMPLOYEE ENGAGEMENT DAN WORK-LIFE BALANCE YANG DI MEDIASI OLEH JOB SATISFACTION TERHADAP TURNOVER INTENTION
Authors: Yuliani Yuliani , Ekhsan Muhamad 
Published: May 2024

Di era globalisasi saat ini, pengelolaan sumber daya manusia menjadi faktor krusial bagi kesuksesan sebuah perusahaan. Jika pengelolaan sumber daya manusia tidak berhasil, perusahaan harus berupaya mempertahankan karyawannya karena karyawan cenderung ingin mengundurkan diri. Keterlibatan karyawan dalam perusahaan berkaitan erat dengan rendahnya keinginan karyawan untuk meninggalkan perusahaan tersebut. Karyawan yang mampu menyeimbangkan pekerjaan dan kehidupan pribadinya mungkin memiliki keinginan yang sangat rendah atau bahkan tidak ada untuk pindah ke tempat lain. Namun, semakin tinggi kepuasan karyawan terhadap pekerjaannya, semakin besar pula keinginannya untuk meninggalkan perusahaan. Penelitian ini dilakukan untuk memahami pengaruh keterlibatan karyawan, keseimbangan kehidupan kerja, serta kepuasan kerja terhadap niat berpindah karyawan PT. EPS Indonesia. Data awal penelitian diperoleh melalui penyebaran kuesioner kepada seluruh karyawan di perusahaan tersebut, dengan menerapkan sampling purposive yang menghasilkan 80 responden. Analisis data kuantitatif dilakukan menggunakan Structural Equation Modeling dengan aplikasi SmartPLS versi 3.0. Hasil penelitian menunjukkan bahwa kepuasan kerja karyawan tidak berdampak signifikan terhadap niat berpindah, dan kepuasan kerja juga tidak memediasi hubungan antara keterlibatan karyawan serta keseimbangan kehidupan kerja dengan niat berpindah. Temuan penelitian ini diharapkan dapat memberikan masukan bagi PT. EPS Indonesia.

In the current era of globalization, human resource management is a crucial factor for the success of a company. If human resource management is not successful, companies must try to retain their employees because employees tend to want to resign. Employee engagement in the company is closely related to the low desire of employees to leave the company. Employees who are able to balance their work and personal lives may have very low or no desire to move elsewhere. However, the higher the employee's satisfaction with their job, the greater the desire to leave the company. This study was conducted to understand the influence of employee engagement, work-life balance, and job satisfaction on the intention to move of PT EPS Indonesia employees. The initial research data was obtained through distributing questionnaires to all employees in the company, by applying purposive sampling which resulted in 80 respondents. Quantitative data analysis was conducted using Structural Equation Modeling with the SmartPLS version 3.0 application. The results showed that employee job satisfaction did not have a significant impact on turnover intention, and job satisfaction also did not mediate the relationship between employee engagement and work-life balance with turnover intention. The findings of this study are expected to provide input for PT EPS Indonesia.
THE IMPACT OF TUNNELING INCENTIVE, BONUS MECHANISM, TAX MINIMIZATION, AND MULTINATIONALITY TO TRANSFER PRICING
Authors: Pranatio Britney , Sutrisno Paulina 
Published: May 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh tunneling incentive, mekanisme bonus, tax minimization, multinationality, leverage dan intangible asset terhadap keputusan transfer pricing pada perusahaan consumer cyclicals dan non-cyclicals yang terdaftar di Bursa Efek Indonesia. Penelitian ini dilakukan karena masih terdapat ketidakkonsistenan pada hasil penelitian sebelumnya dan dilakukan pada periode setelah terjadinya COVID-19 yang menyebabkan adanya beberapa perubahan aturan tarif perpajakan di Indonesia. Populasi dalam penelitian ini adalah seluruh perusahaan dalam sektor consumer cyclicals dan non-cyclicals yang terdaftar di Bursa Efek Indonesia dari tahun 2020 hingga 2022. Sampel penelitian diperoleh menggunakan metode purposive sampling, yang terdiri atas 59 perusahaan yang memenuhi kriteria sampling, dengan jumlah data 236. Pengujian statistik dalam penelitian ini menggunakan metode regresi berganda. Hasil penelitian menunjukkan bahwa multinationality memiliki pengaruh positif terhadap transfer pricing. Namun demikian tunneling incentive, mekanisme bonus, tax minimization, leverage, dan intangible asset tidak berpengaruh terhadap transfer pricing.

This study aims to assess the impact of tunneling incentives, bonus mechanisms, tax minimization, multinationality, leverage, and intangible assets on the decision-making process of transfer pricing in consumer cyclical and non-cyclical companies listed on the Indonesian Stock Exchange. This research was conducted to address the contradictions found in prior research results. It was conducted during the post-COVID-19 period, which witnessed various modifications in the tax rate rules in Indonesia. The population for this study comprises all companies in the consumer cyclical and non-cyclical sectors listed on the Indonesia Stock Exchange from 2020 to 2022. The research sample was acquired using purposive sampling, involving 59 companies that satisfy the sampling requirements, resulting in 236 data points. The study employed the multiple regression approach for statistical testing. The research findings indicate that multinationality has a favorable impact on transfer pricing. However, the concepts of tunneling incentive, bonus mechanism, tax minimization, leverage, and intangible assets do not influence transfer pricing.
Morphometric analysis of transsphenoidal surgery in Peruvian population
Authors: Yataco-Wilcas Christian Alexander , Diaz-Llanes Bruno Eduardo , Coasaca-Tito Yosimar Salomon , Lengua-Vega Luis Alberto , Salazar-Campos Cristian Eugenio 
Published: May 2024

Background:
Transsphenoidal surgery has become a key element in the approach to skull base pathologies. The objective of the study was to explore the morphometry of the sphenoidal region in the Peruvian population, with an emphasis on understanding its specific anatomical characteristics and providing quantitative data for the planning of transsphenoidal surgery.

Methods:
A cross-sectional study included a random sample of 81 cases of healthy individuals who presented to the Radiology Department of a Private Hospital Center in Peru over 1 year. Skull computed tomography scans without contrast were performed, and a detailed morphometric analysis was conducted by an expert neurosurgeon, including measurements of four parameters to evaluate the anatomy of the craniofacial region.

Results:
Most participants exhibited complete sellar pneumatization, followed by incomplete sellar pneumatization, while conchal pneumatization was rare. Significant differences were found between men and women in the distance from the nasal opening to the dorsum of the sella turcica. No significant gender differences were observed in other anatomical measurements or significant changes with age in anatomical measurements.

Conclusion:
Morphometric analysis provides crucial data for the precise customization of surgical interventions in the Peruvian population, especially in transsphenoidal surgery. The results highlight the importance of considering individual anatomical differences and gender variability during surgical planning. Morphometry emerges as a valuable tool to enhance the quality and safety of transsphenoidal surgery by adapting surgical strategies to the specific anatomical dimensions of each patient.
Effect of Comprehensive Nursing Intervention in Patients with Urinary Incontinence After Radical Prostatectomy
Authors: Zhong Haiqin 
Published: May 2024

Objective: To explore and analyze the clinical effect of comprehensive nursing intervention in patients with urinary incontinence after radical prostatectomy. Methods: 84 patients with urinary incontinence after radical prostatectomy admitted to the Urology Department between May 2021 and May 2023 were included in this study. The patients were divided into a comprehensive group and a control group, with 42 cases in each group through a double-blind mechanism. The comprehensive group received comprehensive nursing care, and the control group received primary nursing care. The duration of indwelling urinary catheters and urinary incontinence; psychological performance and living conditions were compared between the two groups. Results: The duration of the indwelling urinary catheter and urinary incontinence of the patients in the comprehensive group were significantly shorter than that in the control group (P < 0.05). Before nursing, there was no statistically significant difference in the anxiety, depression, and other psychological manifestations between the two groups (P > 0.05); after nursing, the comprehensive group’s anxiety, depression, and other psychological manifestations of the comprehensive group were significantly lower than those of the control group (P < 0.05). Before nursing, there was no statistically significant difference in the physical function, mental state, emotional state, and physical recovery of the patients between both groups (P > 0.05); after nursing, the physical function, mental state, emotional state, physical recovery of the patients in the comprehensive group were significantly better than those of the control group. Besides, the living conditions of the patients in the comprehensive group were also significantly better than the control group’s (P < 0.05). Conclusion: Comprehensive nursing intervention can effectively improve symptoms of urinary incontinence after radical prostatectomy, reduce inner pressure, and improve living standards.
Application Value of Nursing Intervention for Patients with Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)
Authors: Shan Haixia , Zhou Wei , Cai Yanyan , Zhou Fang , Hu Yuling 
Published: May 2024

Objective: To explore and analyze the application value of nursing intervention for patients with pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). Methods: From May 2022 to May 2023, 100 patients with pancreatitis after ERCP who were admitted to the General Surgery Department of our hospital were selected as the research objects, they were divided into a research group and a general group by flipping coins, with 50 cases in each group. The research group received nursing intervention, and the general group received general nursing. The postoperative index recovery time, quality of life, and emotional performance were compared between the two groups. Results: The blood amylase recovery time, abdominal pain recovery time, white blood cell recovery time, and hospitalization time in the research group were significantly lower than those in the general group (P < 0.05). Before intervention, the physical function, social factors, physiological performance, emotional state, and other quality of life indicators were compared between the groups, and there was no statistically significant difference (P > 0.05); after intervention, the mentioned quality of life indicators were significantly better than that of the general group (P < 0.05). Before intervention, the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores between the groups were compared, and there was no statistically significant difference (P > 0.05); after intervention, the SAS and SDS scores of the research group were significantly better than those of the general group (P < 0.05). Conclusion: The application of nursing intervention in patients with pancreatitis after ERCP has high clinical value and specific practical significance.
Ukázka působení a činnosti pražského arcibiskupství za arcibiskupa Zbyňka Berky z Dubé a Lipé
Authors: Syslová Anna 
Published: May 2024

Příspěvek je sondou do církevních a náboženských poměrů přelomu 16. a 17. století z perspektivy pražského arcibiskupství prostřednictvím osoby desátého pražského arcibiskupa Zbyňka Berky z Dubé a Lipé (1551–1606). Je představeno arcibiskupovo rodinné zázemí, mocenské pozice nejbližších příbuzných a jeho cesta za církevními beneficii, která je zakončena rokem 1592 a ziskem svatovojtěšského stolce. Následná stěžejní pasáž pojednává o Berkově rekatolizační činnosti a s ní spojené působení nunciů na pražském císařském dvoře. Článek nastiňuje složitou náboženskou situaci doby a způsoby aplikovaného rekatolizačního postupu, který se snaží interpretovat na základě rozboru arcibiskupské korespondence.
Litevci, Estonci a Lotyši: udávání tempa glasnosti a perestrojky v sovětské historiografii
Authors: Lipinsky Jan 
Published: May 2024

Litevci, Estonci a Lotyši: udávání tempa glasnosti a perestrojky v sovětské historiografiiEstonsko, Lotyšsko a Litva byly v důsledku paktu Ribbentrop-Molotov začleněny do Sovětského svazu, čímž se obyvatelé Pobaltí stali národnostními menšinami v rámci sovětského státu. Od druhé světové války bojovaly pobaltské národy proti sovětské hegemonii za zachování své národní identity a znovuzískání suverenity. V tomto boji hrálo stále větší roli připomínání historie, zejména pokud jde o roky 1939 a 1940. Od osmdesátých let 20. století umožnilo úsilí pobaltských zemí stále svobodnější historiografickou a politickou diskuzi. Tyto debaty, prezentace a publikace ukázaly, jak procesy zdola mohou určovat trendy, ovlivňovat politické programy a položit základy pro osvobození jak svých pobaltských vlastí od sovětské hegemonie, tak sovětsko-ruské historiografie od totalitních direktiv. Litevci, Estonci a Lotyši udávali tempo sovětské historiografii v gorbačovské éře. Našli svůj politický hlas a vydláždili cestu svobodné pobaltské budoucnosti.
Anorectal lymphogranuloma venereum among men who have sex with men: a 3-year nationwide survey, France, 2020 to 2022
Authors: Peuchant Olivia , Laurier-Nadalié Cécile , Albucher Laura , Balcon Carla , Dolzy Amandine , Hénin Nadège , Touati Arabella , Bébéar Cécile ,   on behalf of the Anachla study group
Published: May 2024

Background
In France, lymphogranuloma venereum (LGV) testing switched from universal to selective testing in 2016.

Aim
To investigate changes in LGV-affected populations, we performed a nationwide survey based on temporarily reinstated universal LGV testing from 2020 to 2022.

Methods
Each year, during three consecutive months, laboratories voluntarily sent anorectal Chlamydia trachomatis-positive samples from men and women to the National Reference Centre for bacterial sexually transmitted infections. We collected patients’ demographic, clinical and biological data. Genovars L of C. trachomatis were detected using real-time PCR. In LGV-positive samples, the ompA gene was sequenced.

Results
In 2020, LGV positivity was 12.7% (146/1,147), 15.2% (138/907) in 2021 and 13.3% (151/1,137) in 2022 (p > 0.05). It occurred predominantly in men who have sex with men (MSM), with rare cases among transgender women. The proportion of HIV-negative individuals was higher than that of those living with HIV. Asymptomatic rectal LGV increased from 36.1% (44/122) in 2020 to 52.4% (66/126) in 2022 (p = 0.03). Among users of pre-exposure prophylaxis (PrEP), LGV positivity was 13.8% (49/354) in 2020, 15.6% (38/244) in 2021 and 10.9% (36/331) in 2022, and up to 50% reported no anorectal symptoms. Diversity of the LGV ompA genotypes in the Paris region increased during the survey period. An unexpectedly high number of ompA genotype L1 variant was reported in 2022.

Conclusion
In rectal samples from MSM in France, LGV positivity was stable, but the proportion of asymptomatic cases increased in 2022. This underscores the need of universal LGV testing and the importance of continuous surveillance.
Pengaruh Profesional Identity pada Turnover Intention dengan Employee Enggagement dan Job Satisfaction sebagai Variabel Mediasi
Authors: Missye Missye , Hosen Chandra 
Published: May 2024

<p><em> </em><em>The high level of employee turnover intention is an important problem for companies. Companies to make efforts to increase job satisfaction and employee engagement in their work, so that it will have an impact on reducing turnover intentions. Research was conducted on employees to analyze the influence of professional identity on turnover intention with employee engagement and job satisfaction as mediation. This research uses a quantitative approach using a questionnaire filled out by 42 respondents who work at company.. techniques </em><em>probability sampling</em><em> with simple random sampling. The results show that professional identity, job satisfaction and work engagement have a negative influence on turnover intention. </em>Meanwhile, professional identity has a positive effect on employee engagement and job satisfaction. <em>Job satisfaction and employee engagement are able to mediate the influence of professional identity on turnover intention. In an effort to minimize employees turnover intention , companies need to improve their professional identity, which can have an impact on employee engagement and employee job satisfaction which will have the effect of lowering turnover intention.</em></p>
IMPLEMENTASI TEKNOLOGI AUDIT DALAM ERA DIGITAL
Authors: Okinaldi Jefri , Aziza Nurna 
Published: May 2024

Latar Permasalahan ini adalah Implementasi teknologi audit dalam era digital telah menjadi sorotan utama dalam dunia bisnis dan praktik audit. Dalam konteks ini, organisasi bisnis dan praktisi audit semakin mengadopsi teknologi canggih, seperti analisis data, kecerdasan buatan, dan perangkat lunak audit yang terintegrasi. Dalam penelitian ini, peneliti mempergunakan metode kualitatif. Pemilihan metode kualitatif atas dasar penggunaan teknik pengumpulan data dengan kajian teoretis. Penggunaan kajian teoretis ini bermaksud untuk menyelesaikan masalah yang ada di dalam penelitian sesuai sumber dan berpatokan pada penelitian sebelumnya. Hasil penelitian sebelumnya akan peneliti kumpulkan dan melalui tahap analisis supaya memperoleh simpulan. Perkembangan teknologi amat memengaruhi auditor guna membantu auditor dalam pengambilan keputusan. Kehadiran teknologi informasi yang berkembang seperti sekarang, auditor perlu memahami perihal sistem komputer, mengingat sistem ini berdampak signifikan terhadap cara atau prosedur pengambilan keputusan yang dipergunakan oleh auditor.
The Evolution of Nadofaragene Firadenovec: A Review and the Path Forward
Authors: Steinmetz Alexis R. , Mokkapati Sharada , McConkey David , Dinney Colin P. 
Published: May 2024

BACKGROUND: The intravesical gene therapy nadofaragene firadenovec (rAd-IFNα/Syn3) was FDA approved in 2022 for non-muscle invasive bladder cancer (NMIBC) unresponsive to frontline treatment with BCG, and the first gene therapy developed for bladder cancer. This non-replicating recombinant adenovirus vector delivers a copy of the human interferon alpha-2b gene into urothelial and tumor cells, causing them to express this pleotropic cytokine with potent antitumor effects. OBJECTIVE: To provide a historical overview describing how several decades of preclinical and clinical studies investigating the role of interferon in the treatment of bladder cancer ultimately led to the development of gene therapy with nadofaragene for NMIBC. METHODS: We conducted a review of the literature using PubMed, Google Scholar, and ClinicalTrials.gov to summarize our knowledge of the evolution of interferon-based therapy in NMIBC. RESULTS: The FDA approval of this therapy represents an important landmark in urologic oncology and several decades of research dedicated to the study of interferon’s direct and indirect antitumor properties in NMIBC. The data gathered from the phase 1, 2, and 3 clinical trials continue to provide additional insights into the precise mechanisms underlying both the efficacy of and resistance to nadofaragene. CONCLUSIONS: Nadofaragene leverages the cytotoxic, anti-angiogenic, and immune-modulatory roles of interferon to effectively treat NMIBC that is resistant to BCG. Ongoing studies of resistance mechanisms and prognostic biomarkers have been promising; these will ultimately improve patient selection and allow for the modulation of factors in the tumor or immune microenvironment to further increase therapeutic response.