bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Chronic Kidney Disease in Type 1 Diabetes Among Adults in the U.S.
Authors: Rossing Peter , Groop Per-Henrik , Singh Rakesh , Lawatscheck Robert , Tuttle Katherine R. 
Published: June 2024

OBJECTIVE
The prevalence of chronic kidney disease (CKD) in adults ≥18 years of age with type 1 diabetes in the U.S. was determined using National Health and Nutrition Examination Survey (NHANES) data.

RESEARCH DESIGN AND METHODS
A modified treatment-based algorithm applying a subset of NHANES diabetes questionnaires was used. The number of respondents with CKD and type 1 diabetes was weighted (extrapolated) to the U.S. population.

RESULTS
Based on data between 2015 and 2018, type 1 diabetes was identified in 47 out of 19,225 adults with evaluable kidney function data. CKD was present in 20 out of 47 people identified with type 1 diabetes. The weighted estimate of CKD in type 1 diabetes was 21.5%, corresponding to 258,196 (95% CI 71,189–445,203) people in the U.S.

CONCLUSIONS
Applying a conservative approach in our study indicates that CKD is common in adults with type 1 diabetes in the U.S.
The EU’s Digital Markets Act: Regulatory Reform, Relapse or Reversal?
Authors: Boscheck Ralf 
Published: June 2024

Abstract
As of 7 March 2024, the EU Commission began to enforce its controversial Digital Markets Act (DMA). This article sheds light on the recent debate. It lists the dos and don’ts of the DMA as well as stakeholder reactions to them before tracing some of the underlying motivations and reasoning that emerge from the EU’s current policy reversal with reference to dealing with abuse of dominant positions in line with Article 102 of the Treaty on the Functioning of the European Union. Following this, the paper reviews economic aspects of digital platforms, concerns about market foreclosure and essential facility as well as appropriate remedies before closing with a discussion of the challenges in stipulating and enforcing efficient rules to govern digital platforms. It is argued that the DMA ought to be rewritten to stipulate clear and cogent legal standards, return to a strengthened system of ex post control and provide platforms with the opportunity to deliver efficiency defenses as part of corporate self-regulation.
Criminal Law Assessments of the Exploitation of Prostitution Practised by Humanoid Robots
Authors: Lachowski Jerzy 
Published: June 2024

Abstract
The subject of this study is the criminal law issue of exploiting prostitution practised by humanoid robots. Interest in this issue stems from two main reasons. Firstly, the development of new technologies, including artificial intelligence capable of self-education, analysis of the surrounding reality, and decision-making necessitates the consideration of its legal subjectivity. Secondly, the emergence of brothels employing humanoid robots prompts reflection on the criminal responsibility of those who benefit from the prostitution facilitated by them. This article aims to highlight the phenomenon of using humanoid robots in prostitution, offer a criminal law assessment of such behaviour from the perspective of Polish criminal law, and suggest the direction for the development of domestic criminal law to accommodate this phenomenon in the future. Additionally, it addresses the issue of criminal liability for harm caused by a humanoid robot equipped with artificial intelligence while providing sexual services. The article predominantly employs the dogmatic-legal method, performing an exegesis of the provisions of Article 204 of the Criminal Code in the context of the issue signalled. The analyses have concluded that this norm does not encompass in which the perpetrator facilitates, induces prostitution of a humanoid robot or derives financial benefits from such activities, despite such behaviour being detrimental to morality, the fundamental good protected under Article 204 of the Criminal Code. De lege lata, a humanoid robot may also not be subject to criminal liability if it harms a person using its sexual services, as such an ‘essence’ does not align with the current structure of crime and the concept of criminal punishment. However, the liability of manufacturers or users of such devices is not ruled out. It should be noted that as humanoid robots become more autonomous, holding producers or users criminally liable for damages they cause becomes less justifiable, and the applicability of artificial intelligence liability similar to the criminal liability of legal persons becomes more relevant.
Fear and Agitation as the Normative Elements of Legitimate Self-Defence Excess
Authors: Grudecki MichaŁ , Sitarz Olga 
Published: June 2024

Abstract
The authors of this publication have explored the importance of justifying fear and agitation underpinning the transgression of necessary self-defence. According to Article 25 § 2 and 3 of the Criminal Code, they identified five scenarios, differing in how a perpetrator’s mental state is determined, affecting the criminal law consequences of unlawfully infringing on or exposing the aggressor’s legal interests. The authors validated the preliminary hypothesis that the legislator assumed legitimate self-defence excess results from fear or agitation due to the circumstances of the assault, necessitating procedural confirmation. Their occurrence leads to the defender’s impunity, regardless of the type of legal interests infringed and the extent of legitimate self-defence excess. A shortfall in the mental state circumstances of a defender, as referred to in Article 25 § 3 of the Criminal Code in a specific factual state, opens the possibility of applying a general, complementary provision, i.e., Article 25 § 2.
Criminalisation of the So-Called Forced Marriage in the Polish Criminal Law
Authors: Kosonoga-Zygmunt Julia 
Published: June 2024

Abstract
This article discusses the issue of so-called forced marriages, the criminalisation of which was introduced into Polish criminal legislation by the Act of 13 January 2023 amending the Code of Civil Procedure and some other acts. Introducing the provisions of Article 191b into the Criminal Code aims to fulfil the obligation arising from Article 37 of the Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence of 11 May 2011 (Journal of Laws of 2015, item 961). In addition to outlining the statutory features of new types of crimes, the article addresses issues such as criminal liability, the concurrence of regulations, and the issue of the so-called cultural defence.
Formation of Some Elements of the Right to Defence in Misdemeanour Proceedings
Authors: Sowiński Piotr Krzysztof 
Published: June 2024

Abstract
The text analyses normative solutions concerning the right to defence in Polish proceedings in cases of offences. It discusses the formation of selected elements of the right to defence, from the pre-war solutions to modern times. The author highlights the autonomy of the solutions in force in the 2001 Code of Proceedings in Misdemeanour Cases, and their similarities to the right to defence in criminal cases, constituting the most comprehensive model of this right.
Permission for Municipalities to Establish and Finance Prizes and Awards for Athletes in Electronic Sports
Authors: Kuczkowski Przemysław 
Published: June 2024

Abstract
The article, original in nature, was devoted to the issue of awards and prizes for e-sports players. The motivational financial instruments in question are regulated in the Sports Law, specifically in Article 31. The author has attempted to solve the legal problem of finding an answer to the question of the legal possibility for municipalities to establish and finance prizes and awards for e-sports players under Article 31 of the Sports Law. Due to the singular and causal works in the field of e-sports funding, which do not address the issue of establishing and funding prizes and awards for e-sports players under Article 31 of the Sports Act, the elaboration of this issue within the framework of the article will, in the author’s opinion, undoubtedly enrich the current literature on the subject.
The introductory considerations focus on presenting the essence of the definition of sport and attempt to qualify e-sports as a sport under the Sports Act, which is significant for the possibility of local authorities establishing prizes and awards. The key views of the literature, judicial decisions, and the state of the law in this area were presented. Investigations in this area have led to the conclusion that, with a few reservations, it is possible to qualify e-sport as a sport. Subsequently, the focus was on the legal aspects concerning the possibility for municipalities to establish and finance prizes and awards for e-sports players. The problem concerning the understanding of competition under the Sports Act was resolved, and it was pointed out that e-sports players, despite the lack of a Polish e-sports association, can participate in sports competitions under the Sports Act. In addition, the problematic premise concerning the importance of a given sport for a local authority has been clarified. The final considerations in this area have allowed de lege ferenda postulates to be formulated.
The analysis is based on legal norms and statements of doctrine and jurisprudence. The article contains considerations concerning the normative and dogmatic sphere as well as the sphere of law application by administrative courts. The research has a national character. In this article, the dogmatic-legal method has been applied, consisting of the analysis of legal regulations on the establishment and financing of awards and prizes for players of electronic sports.
The subject matter discussed is divided into several main editorial units. The different parts correspond to the main outline of the problem and its relation to important scientific and practical issues.
The Impact of the Kakhovka Dam Destruction on the Water Temperature in the Lower Reaches of the Dnipro River and the Former Kakhovske Reservoir
Authors: Vyshnevskyi Viktor І. , Shevchuk Serhii А. 
Published: June 2024

Abstract
The results of the studies devoted to the consequences of the Kakhovka dam destruction and the empting of the Kakhovske reservoir are presented. The water regime of the lower reaches of the Dnipro River was studied, in particular, the water temperature. The remote sensing data on spatial features of water temperature are given. Significant changes in water temperature are shown both in the lower reaches of the Dnipro River and in the former Kakhovske reservoir. In the first days after the destruction of the dam, due to the mixing, the surface water temperature at the mouth of the Dnipro River dropped significantly. Then the water temperature in the lower reaches of the river approached to that one observed before the destruction. In turn, the former Kakhovske reservoir became a network of river branches and lakes that cannot be compared with the former reservoir. The Dniprovske Reservoir, located upstream, affects the water temperature of this territory, especially the largest branch.
VOSviewer Analysis of Studies on Software Selection in the Logistics Sector
Authors: Doganer Duman Bukra , Adak Mehmet , Güleç Alican 
Published: June 2024

Abstract
Outsourcing in logistics is an important step to reduce costs and increase operational efficiency. In this sense, it is possible to come across outsourcing in many areas of logistics processes. One of the outsourcing steps is the decision to select the software. Choosing the right software can affect the market share of the organization and the implementation time, effort, and cost. The findings of this research will help the marketing and sales teams of software product companies to develop key points and also enable end users to make informed decisions in selecting software packages for the organization. In this study, the studies in the literature were examined through the Scopus database, and co-citation analysis was performed using the VOSviewer program. As a result of the analysis, the articles analyzed were divided into four clusters and explained.
Pathophysiology of paraneoplastic rheumatologic syndromes- could be involved in the diagnosis of a pulmonary adenocarcinoma?
Authors: Budin Corina Eugenia , Pătrîntașu Dariana Elena , Hédi-Katalin Sárközi , Cocuz Iuliu Gabriel , Ianoși Edith Simona , Cotoi Ovidiu Simion 
Published: June 2024

Abstract
Paraneoplastic syndromes are diseases caused by malignancies without direct anatomical relationship with it and it is crucial to realize that paraneoplastic phenomena are not caused by metastases. A paraneoplastic phenomenon can be the first indicator of cancer in an undiagnosed individual, and in severe cases lead to fatality. Various paraneoplastic rheumatological syndromes are associated with malignant neoplasms. Although they occur within various forms of malignancy, they most often suceed lung cancer, and adenocarcinoma stands out as the most prevalent histological subtype within pulmonary cancer. This article focuses on the understanding of paraneoplastic syndromes, particularly regarding paraneoplastic rheumatic syndromes due to their challenging differentiation from idiopathic rheumatic disorders.
Systemic inflammation and obstructive sleep apnea syndrome (OSA): the role of C–reactive protein (CRP)
Authors: Pintilie Adriana-Loredana , Zabara-Antal Andreea , Vasilache-Antohi Paula , Tau Victoria , Stoian Adelina , Trofor Antigona Carmen , Crisan-Dabija Radu 
Published: June 2024

Abstract
The presence of sleep-related disorders, particularly obstructive sleep apnea syndrome (OSA), instigates pathological changes during sleep, giving rise to frequent hypoxic episodes that generate elevated levels of a broad spectrum of inflammatory cytokines. C-reactive protein (CRP), a biomarker signifying the presence and intensity of inflammation, is frequently detected in elevated serum or plasma concentrations, correlating with the number of respiratory events, especially in moderate and severe forms, across both adults and children. Various available therapeutic approaches demonstrate the capacity to diminish serum levels, although the minimum duration of usage typically extends between 2-6 months. In the case of older individuals, OSA commonly coexists with additional conditions, further augmenting the baseline inflammatory level. This accelerated disease progression amplifies mortality rates, incurs heightened costs, and significantly diminishes the overall quality of life.
Enhancing Pulmonary Care: The Pivotal Role of Segmentation and Automated Analysis in Advanced Pulmonary Imaging
Authors: Gheorghiu Radu Marian , Tita Alexandra , Stan Iustina Violeta , Comanici Valentina Daniela , Craiu Mihai 
Published: June 2024

Abstract
In the field of medical imaging, techniques like computed tomography (CT), magnetic resonance imaging (MRI), and X-rays are essential for diagnosing and monitoring diseases, particularly in pulmonary pathology. A significant development in this area is the application of automated segmentation and machine learning, enhancing the accuracy in diagnosing lung diseases, such as lung cancer. However, there remains a knowledge gap in fully understanding the potential and limitations of these technologies, especially across diverse clinical conditions and datasets. To address this gap, the paper delves into the integration of artificial intelligence with conventional imaging techniques, focusing primarily on the use of convolutional neural networks (CNNs) and transformer-based models in automated segmentation. This approach is pivotal in improving the detection rates and accuracy of diagnoses in complex pulmonary diseases. Findings indicate that AI-enhanced imaging significantly advances the early detection of pulmonary diseases, notably lung cancer, and reduces the time until diagnosis. Yet, challenges such as the necessity for diverse and comprehensive training data and the generalizability of algorithms, persist. Moreover, ethical considerations in the deployment of AI technologies in healthcare are crucial. In conclusion, while these technologies mark substantial progress in pulmonary imaging, it is essential to find the balance between technological advancements and ethical considerations. This balance is key to ensuring effective and equitable healthcare, maximizing the benefits of AI in medical imaging while maintaining patient trust and privacy.
DLCO and Spirometry in non-small cell lung cancer patients receiving EGFR-TKI in Indonesia
Authors: Sutarto Riyadi , Yunus Faisal , Zaini Jamal , Faisal Hana Khairina Putri 
Published: June 2024

Abstract

Introduction
EGFR-TKI is the treatment of choice in non-small cell lung cancer (NSCLC) with EGFR mutation in exon 19 or 21. The influence of EGFR-TKI therapy on lung function is still unrecognizable in NSCLC patients.

Objectives
This prospective study aims to examine the influence of EGFR-TKI therapy on lung function of lung adenocarcinoma patients with a single mutation in EGFR exon 19 or 21 at Persahabatan National Respiratory Center Hospital Jakarta, Indonesia. The pulmonary function test (PFT), including spirometry and diffusing capacity (DLCO), was performed before and after three months of EGFR-TKI therapy. After three months, the patients were divided into groups based on the Response Evaluation Criteria in Solid Tumors (RECIST) criteria and the change of PFT was compared before and after therapy.

Results
Among twenty lung cancer patients enrolled, we found increase of predicted mean FVC value from 60.6% to 68.25% (p=0.03), mean predicted FEV1 value from 59.7% to 67.05% (p=0.036), mean DLCO from 11.55 ml/minute/mmHg to 13.72 ml/min/mmHg (p=0.004), and predicted DLCO from 53.4% to 63.85% (p=0.03). The increase of mean predicted DLCO was greatest in the partial response group, which was 16.43% (p=0.056).

Conclusion
This study found that the majority of NSCLC patients with single EGFR exon 19 or 21 mutation had significantly improved lung function after EGFR-TKI therapy. Lung function test might become a beneficial tool to evaluate the effectiveness of EGFR-TKI in NSCLC patients, especially in clinical setting where computerized tomography (CT) scan is not available.
Blue light and its effects on sleep
Authors: Diaconu George-Alexandru , Iordăchel Cătălina Maria , Coca Cătălin , Feraru Nicolae , Gheorghevici Constantin , Zisu Dănuț , Emilia Șandru , Burdușel Beatrice , Popa Andreea , Munteanu Ioana 
Published: June 2024

Abstract
Short wavelenght light (blue light) contributes to dysregulations of the circadian cycles. In an era where most of the light sources were replaced by Light Emitting Diodes (LEDs), a new problem regarding sleep quality and nictemeral cycle appears. Even though blue light is currently being used a treatment for sleep dysregulations and insomnia (through cycle altering), this stimuli activates the melanopsin secretory mechanism via photoreceptor cells and thus supresses the pineal secretion of melatonin. Melatonin plays a crucial role in provoking pre-sleep symptoms, inducing and maintaining sleep, improving sleep quality and multiple other effects dependant to the organ, such as being an antioxidant or its protective atribute against diabetes. This paper is a general review of the literature and brings to a single place multiple studies about the importance of sleep, physiology of melatonin secretion and the effect of light exposure on those aforementioned.
Severe restrictive syndrome in context of bilateral diaphragmatic paralysis - case series
Authors: Diaconu Lorena-Nicoleta , Bobocea Raluca , Macri Anca , Valu Bianca , Popa Ionela 
Published: June 2024

Abstract
The authors present a miniseries of two clinical cases of bilateral diaphragmatic paralysis, of different etiologies, which provide the opportunity to discuss the particularities of the clinical manifestations, the paraclinical investigations necessary to establish a positive diagnosis, the elements of differential diagnosis, the general therapeutic principles addressed to respiratory failure secondary to diaphragmatic paralysis.
Interstitial lung diseases computer-aided imaging diagnosis, using complex networks
Authors: Adriana Trușculescu , Versavia Ancușa , Laura Broască , Diana Manolescu , Camelia Pescaru , Cristian Oancea 
Published: June 2024

Abstract
The article aims to explore how a Complex Network (CN) computer-aided technique targeted for interstitial lung disease (ILD) approach can enhance the work of clinicians and if a CN-based computer-aided diagnosis can provide new data to help manage ILDs more successfully. The CN technique is used to evaluate the progression of the disease by analyzing relevant axial HRCT slices and dynamic CN evaluation using the relative speed for each layer. The article presents the results from a study of 65 patients with interstitial lung disease (ILD), comprising 18 females with a mean age of 59.35 years (ranging from 34 to 76). The initial clinical diagnosis was idiopathic pulmonary fibrosis (IPF) in 28 patients (43.07%), Non-Specific Interstitial Pneumonia (NSIP) in 11 patients, and other ILDs in the remaining patients. Each CT scan fulfilled the criteria for high-resolution CT with constant characteristics across the group. All patients underwent imagistic follow-up for at least 11 months, and additional data were provided for each investigation. The cohort was chosen based on concordant lung function decline and imaging evolution decline. The article concludes that the complex network approach provides both a qualitative visual map and quantitative metrics to enhance ILD diagnosis and progression tracking. The results suggest that a CN-based computer-aided diagnosis can provide new required data to manage ILDs more effectively. This approach may enable clinicians to make more precise conclusions regarding the structure of the analyzed lung area, which can help tailor disease management strategies to individual patient profiles.
Baseline characteristics in patients with interstitial lung diseases as predictors for progression: a real life study
Authors: Teodorescu-Drăghicescu Ștefan , Strâmbu Irina 
Published: June 2024

Abstract
Interstitial lung diseases (ILDs) comprise a large number of different diseases, some of the patients having a progressive evolution toward irreversible fibrosis. The aim of this study is to identify baseline clinical, functional, and imaging characteristics at the date of the diagnosis, that could predict the evolution toward fibrosis.
This is a retrospective descriptive study that included 126 patients diagnosed and followed-up in Department 5 of the Institute of Pneumophtisiology “Marius Nasta” Bucharest between 2014 and 2022.
The authors recorded baseline demographics, symptoms, lung function tests (forced vital capacity – FVC and diffusion capacity – DLCO), high resolution CT (HRCT) imaging features. Patients were followed-up at 6 and 12 months. According to decline in lung function or imaging worsening, patients were divided in2 groups: progressors (60 patients) and non-progressors (26 patients). Baseline characteristics of the 2 groups were compared.
Results: There is an important delay since onset of symptoms to diagnosis (a mean of 17 months). Lower baseline FVC, smoking history, presence of traction bronchiectasis and/or honeycombing and male gender were associated to progressive lung fibrosis.