bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonconservative QFT bounds for tracking error specifications
Authors: Elso Jorge , Gil‐Martínez Montserrat , Garcia‐Sanz Mario 
Published: October 2011

SUMMARYAn alternative to the traditional QFT tracking problem, in which upper and lower tolerances are imposed on the magnitude of the tracking transfer function, is to define the robust specification as a boundary on the deviation of such function from a predefined model. However, previous research exploring this approach reveals a certain overdesign and dependence on the choice of the nominal plant. This paper establishes a necessary condition on the controller from tracking error specifications. With this condition, the controller bounds introduce no overdesign, and the resulting two‐degrees‐of‐freedom design is independent of the choice of the nominal plant, similar to the traditional approach. Copyright © 2011 John Wiley & Sons, Ltd.
Adaptive pattern mining model for early detection of botnet‐propagation scale
Authors: Kim Do Hoon , Lee Taek , Kang Jaewoo , Jeong Hyunchoel , In Hoh Peter 
Published: October 2011

ABSTRACTBotnets are a disastrous threat because they execute malicious activities such as distributed denial‐of‐service, spam email, malware downloads (such as eggdownloads), and spying by exploiting zombie PCs under their control. Botnets infect PCs on a huge scale by initially scanning the service ports of vulnerable applications for the purpose of propagation, which is leveraged as the size of the botnet increases. Therefore, it is of crucial importance to detect botnet‐propagation activities early and to determine the expectedsize of the attack. To address this issue, this paper proposes to recreate botnets' port‐scanning patterns using a simple text classifier that represents these patterns as a kind of matrix. The patterns obtained are then used to train a hidden Markov model and to perform early detection using the trained model. Early detection is achievable by catching the onset of suspicious propagation immediately, and a size estimate is obtained by monitoring fluctuations in botnet size. With this approach, early‐detection rates increased to more than 30.6% on average, with a low false negative rate (less than 6%) and an F‐measure greater than 96%. This significant improvement in performance will contribute to preventing botnet propagation in its earliest stages. Copyright © 2011 John Wiley & Sons, Ltd.
Fathers of Children with Disabilities: Stress and Life Satisfaction
Authors: Darling Carol A. , Senatore Natalie , Strachan John 
Published: October 2011

AbstractAs the role of fathers within families continues to evolve, understanding how these changes impact life satisfaction is needed. This is especially relevant for fathers who have children with disabilities; therefore, this study sought to understand the group differences between fathers of children with and without disabilities. A survey design was used that involved 85 fathers of children with disabilities and 121 fathers of children without disabilities. Analyses indicated that fathers of children with disabilities experienced greater stress in daily parenting hassles, family life events and changes, parenting stress and health stress. In comparison, fathers with children who did not have disabilities had a higher level of coping and greater satisfaction with life. A path‐analysis model based on family stress theory indicated that whether or not fathers had children who were disabled was a major contributor to life satisfaction followed by parenting stress and stress from family life events and changes. These findings provide implications for future research and practice. Copyright © 2011 John Wiley & Sons, Ltd.
An evidence‐based model of distributed software development project management: results from a systematic mapping study
Authors: da Silva Fabio Q. B. , Prikladnicki Rafael , França A. César C. , Monteiro Cleviton V. F. , Costa Catarina , Rocha Rodrigo 
Published: October 2011

ABSTRACTDistributed software development (DSD) has intensified over the past few years, and DSD project management is more complex than collocated project management. However, no systematic research effort has focused on aggregating evidence from the scientific literature to build models to support project management on DSD context. For these reasons, the goal of this paper is to build an evidence‐based model of DSD project management from the research findings about challenges of DSD and the practices, models and tools proposed and used to overcome these challenges. We based the construction of this model on the evidence collected and synthesized by a comprehensive systematic mapping study of 70 research papers published between 1997 and 2009. We believe that our results can help practitioners and researchers to better understand the challenges and implement more effective solutions to improve project management within distributed project management teams. These results also provide a mapping of the research about DSD project management, identifying areas where further research is needed. Copyright © 2011 John Wiley & Sons, Ltd.
Path planning using a mobile anchor node based on trilateration in wireless sensor networks
Authors: Han Guangjie , Xu Huihui , Jiang Jinfang , Shu Lei , Hara Takahiro , Nishio Shojiro 
Published: October 2011

ABSTRACTIn wireless sensor networks (WSNs), many applications require sensor nodes to obtain their locations. Now, the main idea in most existing localization algorithms has been that a mobile anchor node (e.g., global positioning system‐equipped nodes) broadcasts its coordinates to help other unknown nodes to localize themselves while moving according to a specified trajectory. This method not only reduces the cost of WSNs but also gets high localization accuracy. In this case, a basic problem is that the path planning of the mobile anchor node should move along the trajectory to minimize the localization error and to localize the unknown nodes. In this paper, we propose a Localization algorithm with a Mobile Anchor node based on Trilateration (LMAT) in WSNs. LMAT algorithm uses a mobile anchor node to move according to trilateration trajectory in deployment area and broadcasts its current position periodically. Simulation results show that the performance of our LMAT algorithm is better than that of other similar algorithms. Copyright © 2011 John Wiley & Sons, Ltd.
Craftsmen, upstarts and Sufis in the late Mamluk period
Authors: Behrens-Abouseif Doris 
Published: October 2011

AbstractThis article explores the careers of craftsmen and other commoners, who succeeded in joining the bureaucratic system and occupying high positions in the Mamluk administrative establishment, eventually acquiring great power and even political authority. At the same time Sufi shaykhs, also men of common origin and beneficiaries of Mamluk philanthropy, emerged as mighty and authoritative figures, venerated equally by the aristocracy and the populace. The newly privileged groups also figure as founders of Friday mosques following a flexible new attitude on the part of the authorities. This social fluidity, often criticized by historians of the period, was the result of the pious patronage of the Mamluk aristocracy, which brought academic education to the reach of a large part of the populace. Towards the end of the Mamluk period, the structure of religious institutions had itself been levelled: the Friday mosque with Sufi service replaced the earliermadrasas andkhanqāhs. The article also discusses how the visual arts of the period mirror the social changes with new aspects of artistic patronage.
Maternal anaemia in West and Central Africa: time for urgent action
Authors: Ayoya Mohamed Ag , Bendech Mohamed Ag , Zagré Noel Marie , Tchibindat Félicité 
Published: October 2011

AbstractObjectiveTo review the prevalence, severity and determinants of anaemia among women in West and Central Africa (WCA) and raise awareness among policy makers and programme planners in the region.DesignSystematic descriptive review of data in the public domain of the ORC Macro MEASURE Demographic and Health Surveys, national nutrition surveys, oral and technical communications at regional meetings, studies published in scientific journals, and WHO and UNICEF databases.SettingWest and Central Africa region.SubjectsWomen of childbearing age.ResultsThe prevalence of anaemia among pregnant and non-pregnant women is higher than 50 % and 40 %, respectively, in all countries. Within countries, this prevalence varies by living setting (ruralv. urban), women's age and education. Across countries, socio-economic and climatic differences have no apparent association with the prevalence of anaemia among women. Several factors contribute either alone or jointly to the high rates of maternal anaemia in this region. These include widespread nutritional deficiencies; high incidence of infectious diseases; low access to and poor quality of health services; low literacy rates; ineffective design, implementation and evaluation of anaemia control programmes; and poverty.ConclusionsAddressing the multiple causes and minimizing the consequences of anaemia on maternal and child health and development in WCA require integrated multifactorial and multisectoral strategies. This also calls for unprecedented, historical and stronger political will and commitment that put adolescent girls and maternal health at the centre of the development agenda.
Human Heart Development Pathways
Authors: Sklar Samuel , Pico Alexander 
Published: October 2011

AbstractThis pathway has been largely adapted from an article by Deepak Srivastava, Cell. 2006 Sep 22;126(6):1037-48. In this pathway are known transcription factors, miRNAs and regulatory proteins that impact the regional specificity of the human heart. Activating signals are indicated by arrows while inhibitory signals are indicated by T-bars. Special thanks to Kim Cordes for her assistance in revising this pathway, based on recent heart development research. A live version of the pathway can be found at http://www.wikipathways.org/index.php/Pathway:WP1591
Detectability of Estuarine Fishes in a Beach Seine Survey of Tidal Tributaries of Lower Chesapeake Bay
Authors: Williams Branson D. , Fabrizio Mary C. 
Published: October 2011

AbstractDetectability, the probability of encountering a species at a sampling site, is often overlooked in fisheries research despite its potential to obscure inferences on habitat use and lead to biased estimates of abundance. We used occupancy models to explore factors affecting detectability and occupancy (Ψ), the probability that a species inhabits a site, for three fishes frequently captured in Chesapeake Bay seine surveys: young‐of‐the‐year (age‐0) striped bass Morone saxatilis, yearling Atlantic croaker Micropogonias undulatus, and spottail shiner Notropis hudsonius. Twelve repeat‐sampling events occurred during the summers of 2008 and 2009 at 20 sites in the Mattaponi and Pamunkey rivers, Virginia. Although the environmental factors that influenced detection probabilities varied with species, the detectability of all species was positively related to effective net length (i.e., the maximum distance from shore that the seine was deployed). The mean detectability of age‐0 striped bass, which occupied nearly every site (Ψ = 0.99, SE = 0.01), was 0.62 (SE = 0.06) and positively related to mean water temperature during sampling. The detectability of yearling Atlantic croakers was negatively related to water temperature at time of capture and was significantly greater in early summer than in late summer. In early summer, Atlantic croakers occupied all sampling sites; occupancy decreased in late summer (Ψ = 0.86, SE = 0.08) and was positively related to the mean salinity at the site. Unlike with Atlantic croakers, the mean detectability of spottail shiners was significantly greater in late summer than in early summer; detectability was positively related to turbidity at the time of sampling and reflected the increased availability of recently recruited individuals. Spottail shiners occupied fewer sites than did the two other species (Ψ = 0.59, SE = 0.21). Seasonal changes in detectability appeared to reflect changes in catchability associated with fish growth. Determining factors that influence detection probabilities is vital to improving our understanding of habitat use by fish and reducing the variation in fisheries sampling.
Habitats of Age‐0 Sturgeon in the Lower Missouri River
Authors: Ridenour Clayton J. , Doyle Wyatt J. , Hill Tracy D. 
Published: October 2011

AbstractLittle is known about the habitats of young pallid sturgeon Scaphirhynchus albus and shovelnose sturgeon S. platorynchus. Therefore, we compared the distribution and abundance of age‐0 fish of these species collected in benthic trawls among most of the mesoscale habitats comprising the channelized lower Missouri River (i.e., rock‐dike channel modifying structures, large‐channel sandbar, bankline, tributary, floodplain, and wooded island) from 2007 through 2009. Most age‐0 sturgeon were less than 110 mm (fork length) by the end of the growing season. Age‐0 fish were most frequently collected in areas with a relatively fast bottom velocity (0.5–0.7 m/s) associated with channel sandbars, rootless‐dikes, and wing‐dikes and were rarely found at L‐dikes, along banklines, or in tributaries where bottom velocity was slower (≤0.2 m/s). Age‐0 sturgeon habitat use in the lower Missouri River supports the hypothesis that main‐channel areas are important habitats throughout the life cycle of some fluvial specialist species. In light of existing literature on habitat use by wild age‐0 sturgeon, our results highlight their complex ecology in contemporary large rivers throughout their range. Therefore, we do not predict the response of pallid sturgeon to contemporary habitat restoration goals but discuss current knowledge gaps important to characterizing the early life history of Scaphirhynchus spp. Habitat restoration design on the Missouri River should consider the impact on ecosystem structure and the response by early life stages of these species.
Gene‐by‐environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma
Authors: Bunyavanich S. , Boyce J. A. , Raby B. A. , Weiss S. T. 
Published: October 2011

SummaryBackgroundDistinct receptors likely exist for leukotriene (LT)E4, a potent mediator of airway inflammation. Purinergic receptor P2Y12 is needed for LTE4‐induced airways inflammation, and P2Y12 antagonism attenuates house dust mite‐induced pulmonary eosinophilia in mice. Although experimental data support a role for P2Y12 in airway inflammation, its role in human asthma has never been studied.ObjectiveTo test for association between variants in the P2Y12 gene (P2RY12) and lung function in human subjects with asthma, and to examine for gene‐by‐environment interaction with house dust mite exposure.MethodsNineteen single nucleotide polymorphisms (SNPs) in P2RY12 were genotyped in 422 children with asthma and their parents (n = 1266). Using family based methods, we tested for associations between these SNPs and five lung function measures. We performed haplotype association analyses and tested for gene‐by‐environment interactions using house dust mite exposure. We used the false discovery rate to account for multiple comparisons.ResultsFive SNPs in P2RY12 were associated with multiple lung function measures (P‐values 0.006–0.025). Haplotypes in P2RY12 were also associated with lung function (P‐values 0.0055–0.046). House dust mite exposure modulated associations between P2RY12 and lung function, with minor allele homozygotes exposed to house dust mite demonstrating worse lung function than those unexposed (significant interaction P‐values 0.0028–0.040).Conclusions and Clinical RelevanceThe P2RY12 variants were associated with lung function in a large family‐based asthma cohort. House dust mite exposure caused significant gene‐by‐environment effects. Our findings add the first human evidence to experimental data supporting a role for P2Y12 in lung function. P2Y12 could represent a novel target for asthma treatment.
Poor relevance of a lymphocyte proliferation assay in lamotrigine‐induced Stevens–Johnson syndrome or toxic epidermal necrolysis
Authors: Tang Y. H. , Mockenhaupt M. , Henry A. , Bounoua M. , Naldi L. , Le Gouvello S. , Bensussan A. , Roujeau J. C. 
Published: October 2011

SummaryBackgroundPrior use of ‘lymphocyte transformation test’ (LTT) in Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) provided conflicting results, possibly dependent on sampling dates (acute vs. late).ObjectiveEvaluation of LTT in patients with SJS or TEN who reacted to lamotrigine (LTG). In a small subgroup we explored the possible role of regulatory T cells (T‐reg).MethodsAcute phase samples (9) and post‐recovery samples (14) from cases of SJS or TEN to LTG were provided by the RegiSCAR‐study group. Controls were persons never exposed to LTG (12), patients exposed without reaction (6), and patients who developed a mild eruption to LTG (6). LTT was performed by measuring 3H‐thymidine incorporation after 3 days of incubation with phytohemmaglutinin, LTG (10 μg/mL) or medium. Stimulation index ≥ 2 was considered positive. In 16 cases LTT was redone after depletion of T‐reg by fluorescence activated cell sorting.ResultsPositive LTT was observed in 3/6 cases of mild eruptions, 1/9 SJS/TEN‐cases tested during the acute phase and 3/14 SJS/TEN‐cases tested after recovery. We noted a very mild and nonsignificant trend for an increased response after depletion of T‐reg in late samples from SJS or TEN patients.Conclusions and Clinical RelevanceWith the largest number of LTT performed in patients with SJS or TEN to a single drug, we confirmed that reactive cells are rarely detected in these reactions. Poor reactivity did not seem related to T‐reg. Other in vitro assays than those testing proliferation should be evaluated, before raising the hypothesis that specific cells disappeared by undergoing apoptosis during the reaction.
Effects of music therapy on anxiety of patients with breast cancer after radical mastectomy: a randomized clinical trial
Authors: Li Xiao‐Mei , Zhou Kai‐Na , Yan Hong , Wang Duo‐Lao , Zhang Yin‐Ping 
Published: October 2011

li x.‐m., zhou k.‐n., yan h., wang d.‐l. & zhang y.‐p. (2011) Effects of music therapy on anxiety of patients with breast cancer after radical mastectomy: a randomized clinical trial. Journal of Advanced Nursing 68(5), 1145–1155.AbstractAim.  This paper is a report of a clinical trial of the effects of music therapy on anxiety of female breast cancer patients following radical mastectomy.Background.  There is insufficient evidence on the effects of music therapy on state anxiety of breast cancer patients following radical mastectomy.Methods.  A Hall’s Core, Care, and Cure Model‐based clinical trial was conducted in 120 female breast cancer patients from March to November 2009. A randomized controlled design was utilized. The patients were randomly allocated to the experimental group (n = 60) received music therapy in addition to routine nursing care, and the control group (n = 60) only received routine nursing care. A standardized questionnaire and the State Anxiety Inventory were applied. The primary endpoint was the state anxiety score measured at pretest (on the day before radical mastectomy) and at three post‐tests (on the day before patients were discharged from hospital, the second and third time of admission to hospital for chemotherapy respectively).Results.  The pretest score revealed that the majority of the patients had a moderate level (77·5%) and 15% had severe level of state anxiety. The repeated‐measure ancova model analysis indicated that the mean state anxiety score was significantly lower in the experimental group than those in the control group at each of the three post‐test measurements. The mean difference between the experimental and control group together with 95% confidence intervals were −4·57 (−6·33, −2·82), −8·91 (−10·75, −7·08) and −9·69 (−11·52, −7·85) at the 1st post‐test, 2nd post‐test and 3rd post‐test respectively.Conclusion.  Music therapy is found to have positive effects on decreasing state anxiety score.
The Ultimate Irrelevance Proposition in Finance?
Authors: Karolyi G. Andrew 
Published: October 2011

AbstractI survey 457 published papers in top finance journals across two decades to assess whether these papers misuse tests of significance. More than 80% of published studies are diligent about distinguishing between statistical and economic significance and quantifying and interpreting the economic magnitudes of the statistical relationships they measure. Yet, only 10% of these acknowledge limits to the power of their tests and even fewer do anything about them. Recent demographic trends in publishing, such as larger co‐author teams and increased participation by non‐North American scholars, women, and those outside the top finance departments are not associated with these outcomes.
Anti‐inflammatory effects and the underlying mechanisms of action of daidzein in murine macrophages stimulated with Prevotella intermedia lipopolysaccharide
Authors: Choi E.‐Y. , Jin J.‐Y. , Lee J.‐Y. , Choi J.‐I. , Choi I. S. , Kim S.‐J. 
Published: October 2011

Choi E‐Y, Jin J‐Y, Lee J‐Y, Choi J‐I, Choi IS, Kim S‐J. Anti‐inflammatory effects and the underlying mechanisms of action of daidzein in murine macrophages stimulated with Prevotella intermedia lipopolysaccharide. J Periodont Res 2012; 47: 204–211. © 2011 John Wiley & Sons A/SBackground and Objective:  Host modulatory agents directed at inhibiting specific proinflammatory mediators could be beneficial in terms of attenuating periodontal disease progression and potentially enhancing therapeutic responses. The aim of this study was to investigate whether daidzein could modulate the production inflammatory mediators in macrophages stimulated with lipopolysaccharide (LPS) from Prevotella intermedia, a pathogen implicated in periodontal disease, and to delineate underlying mechanisms of action.Material and Methods:  LPS was extracted from P. intermedia ATCC 25611 cells by the standard hot phenol–water method. The amounts of nitric oxide (NO) and interleukin‐6 (IL‐6) secreted into the culture medium were assayed. A real‐time PCR was performed to quantify inducible nitric oxide synthase (iNOS) and IL‐6 mRNA expression. We used immunoblot analysis to characterize iNOS protein expression, phosphrylation of c‐Jun N‐terminal kinase (JNK) and p38, degradation of inhibitory κB‐α (IκB‐α), nuclear translocation of nuclear factor‐κB (NF‐κB) subunits and phosphorylation of signal transducer and activator of transcription 1 (STAT1). The DNA‐binding activity of NF‐κB was assessed by using ELISA‐based kits.Results:  Daidzein significantly inhibited the production of NO and IL‐6, as well as their mRNA expression, in P. intermedia LPS‐treated RAW264.7 cells. The JNK and p38 pathways were not involved in the regulation of LPS‐induced NO and IL‐6 release by daidzein. Daidzein inhibited the degradation of IκB‐α induced by P. intermedia LPS. In addition, daidzein suppressed NF‐κB transcriptional activity via regulation of the nuclear translocation and DNA‐binding activity of NF‐κB p50 subunit and blocked STAT1 phosphorylation.Conclusion:  Although additional studies are required to dissect the molecular mechanism of action, our results suggest that daidzein could be a promising agent for treating inflammatory periodontal disease. Further research in animal models of periodontitis is necessary to better evaluate the potential of daidzein as a novel therapeutic agent to treat periodontal disease.