bluuebunny/crossref_metadata_2025_split huggingface dataset:
High temperature triggers the metabolism of S‐nitrosothiols in sunflower mediating a process of nitrosative stress which provokes the inhibition of ferredoxin–NADP reductase by tyrosine nitration
Authors: CHAKI MOUNIRA , VALDERRAMA RAQUEL , FERNÁNDEZ‐OCAÑA ANA M. , CARRERAS ALFONSO , GÓMEZ‐RODRÍGUEZ MARIA V. , LÓPEZ‐JARAMILLO JAVIER , BEGARA‐MORALES JUAN C. , SÁNCHEZ‐CALVO BEATRIZ , LUQUE FRANCISCO , LETERRIER MARINA , CORPAS FRANCISCO J. , BARROSO JUAN B. 
Published: June 2011

ABSTRACTHigh temperature (HT) is considered a major abiotic stress that negatively affects both vegetative and reproductive growth. Whereas the metabolism of reactive oxygen species (ROS) is well established under HT, less is known about the metabolism of reactive nitrogen species (RNS). In sunflower (Helianthus annuus L.) seedlings exposed to HT, NO content as well as S‐nitrosoglutathione reductase (GSNOR) activity and expression were down‐regulated with the simultaneous accumulation of total S‐nitrosothiols (SNOs) including S‐nitrosoglutathione (GSNO). However, the content of tyrosine nitration (NO2‐Tyr) studied by high‐performance liquid chromatography with tandem mass spectrometry (LC–MS/MS) and by confocal laser scanning microscope was induced. Nitroproteome analysis under HT showed that this stress induced the protein expression of 13 tyrosine‐nitrated proteins. Among the induced proteins, ferredoxin–NADP reductase (FNR) was selected to evaluate the effect of nitration on its activity after heat stress and in vitro conditions using 3‐morpholinosydnonimine (SIN‐1) (peroxynitrite donor) as the nitrating agent, the FNR activity being inhibited. Taken together, these results suggest that HT augments SNOs, which appear to mediate protein tyrosine nitration, inhibiting FNR, which is involved in the photosynthesis process.
Characterization and interpretation of discontinuity surfaces in a Jurassic ramp setting (High Atlas, Morocco)
Authors: CHRIST NICOLAS , IMMENHAUSER ADRIAN , AMOUR FRÉDÉRIC , MUTTI MARIA , TOMÁS SARA , AGAR SUSAN M. , ALWAY ROBERT , KABIRI LAHCEN 
Published: June 2011

AbstractDiscontinuity surfaces are widely recognized but often poorly understood features of epeiric carbonate settings. In sedimentary systems, these features often represent hiatus surfaces below biostratigraphic resolution and may represent a considerable portion of the time contained in the sediment record. From an applied perspective, discontinuities may represent horizontal flow barriers and result in reservoir compartmentalization. Here, a total of 80 condensed surfaces (S1), firmgrounds (S2) and hardgrounds (S3) from a Jurassic (Middle and Upper Bajocian Assoul Formation) ramp setting of the High Atlas in Morocco are carefully documented with respect to their morphology, their secondary impregnation by Fe and Mn oxides and phosphates and their palaeoecological record. A statistical frequency distribution of two surfaces of the S1 type, 1·1 surfaces of the S2 type and 0·4 surfaces of the S3 type per 10 section metres is observed along a 220 m long carbonate succession. Based on two stratigraphically and spatially separated study windows and correlative sections, the stratigraphic frequency distribution, the lateral extent and the nature of facies change across discontinuities are documented in a quantitative manner. Specific features of the study site include the considerable stratigraphic thickness of the Assoul Formation and the conspicuous absence of subaerial‐exposure‐related features. Based on the data presented here, firmground and hardground surfaces are best interpreted as maximum‐regression‐related features. Relative sea‐level lowstand results in a lowered wave base, and wave orbitals and currents result in sea floor omission and lithification. Care must be taken to avoid overly simplistic interpretations, as differences in bathymetry and carbonate facies result in marked changes in discontinuity characteristics in proximal–distal transects. The data shown here are of significance for those concerned with the interpretation of shoal water carbonate environments and are instrumental in the building of more realistic carbonate reservoir flow models.
Effects of dietary pyridoxine on haemato‐immunological responses ofLabeo rohitafingerlings reared at higher water temperature
Authors: Akhtar M. S. , Kumar Pal A. , Sahu N. P. , Ciji A. , Kumar N. 
Published: June 2011

SummaryA sixty‐day feeding trial was carried out to elucidate the effect of dietary pyridoxine (PN) on hemato‐immunological parameters inLabeo rohitafingerlings exposed to an elevated temperature (ET) of 33 °C. Two hundred and seventy fingerlings (6.71 ± 0.32 g) were randomly distributed into six treatments in triplicates (15 fish/tank). Five iso‐nitrogenous (356.3 ± 2.7 g/kg crude protein) purified diets were prepared with graded levels (0, 10, 50, 100 and 200 mg/kg diet) of PN. Six treatment groups were P10T26 (10 mg PN + ambient temperature (26 °C), P0T33 (0 mg PN + ET), P10T33 (10 mg PN + ET), P50T33 (50 mg PN + ET), P100T33 (100 mg PN + ET) and P200T33 (200 mg PN + ET). The responses ofL. rohitafingerlings to dietary PN were assessed in terms of growth and by analysing some hemato‐immunological parameters. When PN supplementation increased from 10 to 200 mg/kg diet, a significant improvement in weight gain percentage was observed. Erythrocyte (RBC) count, leucocyte (WBC) count, haemoglobin content and respiratory burst activity were significantly (p < 0.05) higher in 100 mg PN/kg diet–fed group than their non‐PN‐fed counterpart. Also, serum albumin, globulin and lysozyme activity were found significantly (p < 0.05) higher in PN‐fed groups. The overall results indicated that dietary PN supplementation at 100 mg/kg diet may reverse the negative effects caused by ET and may protect the haemato‐immunological status ofL. rohitafingerlings reared at higher water temperature.
Do multiple renal arteries in the remnant kidney have a negative influence on kidney donors after kidney donation?
Authors: MA LU‐LIN , LI GANG , HUANG YI , HOU XIAO‐FEI , ZHAO LEI , WANG GUO‐LIANG , TANG WEN‐HAO , CHEN YING‐TAO 
Published: June 2011

ABSTRACT:Aim:  To investigate whether the presence of multiple renal arteries in the remnant kidney has implications for lower renal function or increased incidence of hypertension.Methods:  We reviewed the intraoperative and follow‐up data of 101 live kidney donors who underwent nephrectomies at our institution. Sixty‐nine donors (68.3%) had single artery in the remnant kidney (Group A), while 32 donors (31.7%) had multiple renal arteries in the remnant kidney (Group B). We compared the demographic and intraoperative data between the two groups. The follow‐up data of donors in each group were divided into three subgroups based on the length of the follow‐up period (12–24 months, 24–48 months and ≥48 months). Subgroups were created based on blood pressure and serum creatinine level. The δblood pressure (follow‐up blood pressure minus preoperative blood pressure) and δserum creatinine (follow‐up serum creatinine minus preoperative serum creatinine) in each subgroup in Group A were compared with the counterparts in Group B.Results:  Renal arterial stenosis and calcification of renal arterial wall were not observed in all donors. There were no significant differences in the intraoperative characteristics (e.g. age, body mass index, operative duration and estimated blood loss) between the two groups. In addition, the blood pressure and serum creatinine level among subgroups within each group were similar. Furthermore, significant differences in δblood pressure and δserum creatinine were not observed between subgroups within the same follow‐up period. Recipient survival rate and serum creatinine level were similar and acceptable in both groups.Conclusions:  The presence of multiple renal arteries in the remnant kidney does not have additional negative influence on kidney donors after kidney donation.
The Joanna Briggs Institute Best Practice Information Sheet: The effectiveness of pelvic floor muscle exercises on urinary incontinence in women following childbirth
Authors:   The Joanna Briggs Institute
Published: June 2011

AbstractThis Best Practice Information Sheet is derived from 21 studies and aims to synthesize the best available evidence on the effectiveness of pelvic floor muscle exercises on urinary incontinence in women following childbirth. The information that is contained in this sheet has been derived from studies that were included in a systematic review that was conducted by the Joanna Briggs Institute. The original references can be sourced from the systematic review. Pregnancy and childbirth are major risk factors for the development of urinary incontinence as the muscles of the pelvic floor become stretched and weakened. For some women, such incontinence after childbirth is temporary, but for others, their suffering can be of much longer‐term duration. A number of risk factors has been identified for urinary incontinence following childbirth, including antenatal urinary incontinence, obesity, and significant perineal trauma. The aim of pelvic floor muscle exercises is to strengthen the perivaginal and perianal musculature in order to increase a woman's control of urinary leakage.
Successful pregnancy after simultaneous pancreas‐kidney transplantation from a brain‐dead donor: The first case report in Japan
Authors: Koyama Shinsuke , Tomimatsu Takuji , Kanagawa Takeshi , Daimon Emiko , Kimura Tadashi , Kuroda Akio , Tanemura Masahiro , Doki Yuichiro , Ito Toshinori 
Published: June 2011

AbstractSimultaneous pancreas‐kidney transplantation is a revolutionary medical procedure to cure diabetes mellitus and its complications in one step. For women with type 1 diabetes mellitus and end‐stage renal disease, this procedure not only treats their disease but may also allow them to have children. Worldwide, 77 pregnancies from 43 pancreas‐kidney recipients have been reported. Here, we present the first case report of successful pregnancy after simultaneous pancreas‐kidney transplantation from a brain‐dead donor in Japan. She conceived spontaneously 32 months after transplantation. Her pregnancy course was favorable except for mild rejection of the grafted pancreas and development of gestational diabetes. She delivered a 2882‐g healthy infant in October 2010. Pregnancy after simultaneous pancreas‐kidney transplantation is discussed.
Disseminated intravascular coagulation as the presenting sign of gastric cancer during pregnancy
Authors: Takai Hiroshi , Kondoh Eiji , Sato Yukiyasu , Kakui Kazuyo , Tatsumi Keiji , Konishi Ikuo 
Published: June 2011

AbstractGastric cancer during pregnancy is rare and the outcome is generally poor. A 36‐year‐old woman in the 28th week of gestation was complicated with disseminated intravascular coagulation (DIC), and she was diagnosed with gastric cancer with bone marrow metastasis. Cesarean delivery followed by sequential methotrexate (100 mg/m2) and 5‐fluorouracil (600 mg/m2) chemotherapy was conducted. DIC was successfully managed with blood transfusion and chemotherapy. She has received chemotherapy in the outpatient clinic. This report is the second case of a pregnant woman with DIC as the initial manifestation of advanced gastric cancer. Prompt diagnosis and chemotherapy increases the chances of a relatively favorable outcome even in advanced gastric cancer presenting with DIC due to bone marrow involvement.
Expression of vascular endothelial growth factor C correlates with a poor prognosis based on analysis of prognostic factors in patients with cervical carcinomas
Authors: Ma De‐mei , Xu Yong‐ping , Zhu Lin 
Published: June 2011

AbstractAim:  The aim of this study was to specifically investigate the clinicopathological role of expression of vascular endothelial growth factor C (VEGF‐C) as well as the correlation with clinical outcomes in cervical cancer.Method:  We carried out a comparative analysis of data from a prospective observational study of 82 patients with cervical carcinomas who underwent radical hysterectomy with bilateral adnexectomy and bilateral pelvic lymphadenectomy from January 2001 to January 2005.Results:  VEGF‐C mRNA was identified in tumor tissues from 42 patients. In univariate analysis by Fisher's exact probability test, VEGF‐C expression was significantly associated with lymph node metastasis (LNM) (pN1) (P < 0.01). In multivariate analysis by Binary logistic regression analysis, LNM was the independent relevant factor for VEGF‐C mRNA expression in tumor tissues. In univariate analysis by the log–rank test, the overall 5‐year survival rate of the patients with VEGF‐C mRNA expression in tumor tissues was significantly lower than that of the patients without VEGF‐C mRNA expression (47.6% vs 87.5%; P < 0.01). The overall 5‐year survival rate of the patients with LNM was significantly lower than that of the patients without LNM (50.0% vs 80.4%; P < 0.01). According to Cox regression multivariate analysis, VEGF‐C mRNA expression in tumor tissues and LNM were independent, relevant factors for 5‐year survival rate, respectively.Conclusions:  Expression of VEGF‐C is related to lymph node metastasis (pN1), and is a prognostic indicator for cervical cancer.
Rebuilding the labor curve during neuraxial analgesia
Authors: Frigo Maria Grazia , Larciprete Giovanni , Rossi Federica , Fusco Paolo , Todde Cristina , Jarvis Sheba , Panetta Valentina , Celleno Danilo 
Published: June 2011

AbstractAim:  The aim of this study was to examine the pattern of labor progression among nulliparous women under neuraxial analgesia to obtain a new, specific reference labor curve and to compare the different effects of epidural and combined spinal epidural (CSE) analgesia on the progression of labor.Material and Methods:  This perspective cohort study was carried out in the Obstetrics and Gynecology tertiary care unit. Six hundred nulliparous parturients were enrolled. A total of 545 nulliparous women were assigned to receive either epidural (272) or CSE (273) analgesia during labor.Results:  The mean duration of the first stage was 4 h and 30 min (SD 1.52 h) and the mean duration of the second stage was 1 h and 10 min (SD 0.43). In the second stage, the CSE analgesia labors showed an overall faster progression compared to the epidural labors but both lasted longer than the duration reported by Zhang (53 min) and Friedman (39 min). Both the first and the second‐stage duration were significantly lower if neuraxial analgesia was performed as a CSE procedure with respect to the simple epidural procedure (first stage 4 h and 1 min vs 4 h and 60 min, P = 0.043; second stage 1 h and 5 min vs 1 h and 15 min, P = 0.0356).Conclusions:  The pattern of labor progression in contemporary obstetrics differs significantly from the Friedman curve. Based on these observations, we can obtain a more comprehensive knowledge of the partogram's modifications due to the analgesia.
Rate of negative appendectomy in pregnant women in Benin City, Nigeria
Authors: Agholor Kingsley , Omo‐Aghoja Lawrence , Okonofua Friday 
Published: June 2011

AbstractAim:  This study was an analysis of women diagnosed with acute appendicitis in pregnancy, to appraise the maternal and fetal outcomes and explore the correlations with negative appendectomy.Material and Methods:  A retrospective study was undertaken at the University of Benin Teaching Hospital, Nigeria. The service delivery records of all pregnant women who underwent appendectomy for acute appendicitis from January 2000 to December 2009 were analyzed.Results:  Among 16 173 deliveries, 23 pregnant women were diagnosed with acute appendicitis. The age of the women ranged between 15 and 34 years (median = 26 years), while the majority (65.2%) were nulliparous. The mean gestational age at presentation was 21.1 ± 6.9 weeks with up to 15 (65.2%) patients presenting in the second trimester. Eighteen (78.3%) patients had histopathologically proven appendicitis giving a negative appendectomy rate of 21.7%. Postoperative complications were noted in eight (34.8%) patients. Half of these occurred within the negative appendectomy group. The negative appendectomy group also contributed significantly to the adverse obstetric outcome: preterm labor, 8.7% of 21.7%, preterm delivery, 4.5% of 13.6% and a fetal loss rate of 4.3% of 13%. One maternal death occurred in the group with diseased appendix giving a maternal mortality rate of 4.3%.Conclusions:  While a higher index of suspicion among clinicians will ensure earlier diagnosis and improve the associated maternal and fetal prognosis, the need to reduce the negative laparotomy rate is highlighted by the high rate of adverse obstetric outcomes amongst the negative appendectomy group.
Historic and recent fragmentation coupled with altitude affect the genetic population structure of one of the world's highest tropical tree line species
Authors: Hensen Isabell , Cierjacks Arne , Hirsch Heidi , Kessler Michael , Romoleroux Katya , Renison Daniel , Wesche Karsten 
Published: June 2011

ABSTRACTAim  To assess the effects of altitude and historic and recent forest fragmentation on the genetic diversity and structure of the wind‐pollinated tropical tree line species Polylepis incana.Location  One of the highest mountain forest regions of the world, located in the Eastern Cordillera of the Ecuadorian Andes.Methods  We compared genetic diversity and structure of adult trees with those of seedlings (n= 118 in both cases) in nine forest stands spanning an altitudinal gradient from 3500 to 4100 m a.s.l. using amplified fragment length polymorphisms (AFLPs). Genetic diversity was calculated as percentage of polymorphic bands (P) and Nei's expected heterozygosity (He); genetic differentiation was assessed using analysis of molecular variance, ΦST statistics and Bayesian cluster analysis.Results  Estimates of genetic diversity at the population level were significantly lower in seedlings than in adults. Genetic diversity (He‐value) was, in both cases, negatively correlated to altitude and positively correlated to population size in the seedlings. Genetic differentiation of the seedlings was approximately as high (φST= 0.298) as that of the adults (φST= 0.307), and geographical differentiation was clearly reflected in both AFLP profiles, with mountain ridges acting as barriers to gene flow.Main conclusions  Our study provides evidence of a historic upslope migration of P. incana in central Ecuador. In addition, it highlights the detrimental effects of unexpectedly strong genetic isolation, both recent and historical, particularly for our wind‐pollinated species where the distance between forest stands was less than 25 km. We therefore additionally propose that in habitats with pronounced high‐mountain landscape structures, gene flow may be hampered to such an extent that species have a more pronounced sensitivity to habitat fragmentation, even among populations of wind‐pollinated trees.
READING AUGUSTINE THROUGH JOB: A REPARATIVE READING OF AUGUSTINE'S DOCTRINE OF PREDESTINATION
Authors: TICCIATI SUSANNAH 
Published: June 2011

AbstractIn this article I argue that Augustine's four late works against the so‐called “Semi‐Pelagians” can be read creatively and reparatively alongside the book of Job. Specifically, Augustine's frequent appeals to the inscrutability of God's judgment can be compared with God's speeches to Job out of the whirlwind. Having shown how the latter operate “indexically”, I will return to Augustine to highlight signs of indexicality throughout his four works. This will allow an interpretation of Augustine's doctrine of predestination, and its culminating moments of inscrutability, not as timeless truth, but as a tool used within prayer and preaching to foster salvation.
THE MODERNITY OF CHRISTIAN THEOLOGY OR WRITING KIERKEGAARD AGAIN FOR THE FIRST TIME
Authors: JORDAN MARK D. 
Published: June 2011

AbstractFrom his first book forward, Stanley Cavell has responded to modernity's demands upon philosophic writing. He has also turned from time to time to remark on the situation of Christian speech or its theological elaboration, especially when commenting on Kierkegaard. Implicit in both gestures are questions about whether Christian theology has ever become modern in Cavell's sense—has ever responded to modernity as a crisis in its relation to received forms. If writers of Christian theology take nothing else from Cavell, they should at least carry away some sense of the demand that Kierkegaard puts on any theology written after him.
“A GREATEST MIRACLE”: STANLEY CAVELL, MORAL PERFECTIONISM, AND THE ASCENT INTO THE ORDINARY
Authors: DE VRIES HENT 
Published: June 2011

AbstractWhat to make of “the ordinary,”“the everyday,” and their common “eventfulness”? What to think of what Veena Das, in her recent book Life and Words, prefaced by Stanley Cavell, has called our need to “descent into the ordinary”? Is there a parallel figure of “ascent,” again, into the same “ordinary,” that we might we want to juxtapose with it and that resembles the motif of “change,” even “conversion,” that Cavell analyzes at some length in The Claim of Reason and throughout his oeuvre as a whole? And what could be our reasons for doing so? This essay will draw on Cavell's reading of Ibsen's work in the volume Cities of Words to spell out what such an “ascent” might mean.
PHILOSOPHY AS TRAGEDY OR WHAT WORDS WON'T GIVE
Authors: WARD GRAHAM 
Published: June 2011

AbstractThis article examines Cavell's problematic understanding of scepticism and the knowledge of other minds with respect to his long preoccupation with tragedy. I point to the meta‐philosophical questions Cavell continually raises but fails to address such that a philosophy as tragedy is frequently announced. Taking the same meta‐philosophical questions raised by the inability of words to give us access to certain knowledge, I then rethink this problematic theologically. I show the way Cavell hints at a Christology and a doctrine of analogy neither of which he develops. In developing these two theologoumenon I make some observations on the relationship between theology, philosophy and the endemic potential of the tragic.
FINITUDE AND ORIGINAL SIN: CAVELL'S CONTRIBUTION TO THEOLOGY
Authors: DAHL ESPEN 
Published: June 2011

AbstractStanley Cavell's relation to theology is by no means settled nor is, more generally, his relation to religion. The noted American philosopher's own remarks on these topics are notoriously ambiguous and the commentary literature offers no univocal answer. Taking my cue from Cavell's own suggestions, I argue that there is indeed a fruitful way of positively understanding his relation to religion that proves generative for theology as well. Cavell's highly original understanding of the link between finitude and what he calls scepticism sheds light on the dynamics inherent in the Christian doctrine of original sin.
Noncirrhotic hyperammonaemic encephalopathy
Authors: Laish Ido , Ben Ari Ziv 
Published: June 2011

AbstractAdult hyperammonaemia is associated with severe liver disease in 90% of cases. In the remainder, noncirrhotic causes should be considered. Measurements of serum ammonia level must be part of the basic work‐up in all patients presenting with encephalopathy of unknown origin, even when liver function is normal. Clinician awareness of noncirrhotic hyperammonaemic encephalopathy can contribute to early diagnosis and the initiation of sometimes life‐saving treatment. This review focuses on the physiology, aetiology and underlying mechanisms of noncirrhotic hyperammonaemic encephalopathy and discusses the available treatment modalities.