bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using policy codesign to achieve multi-sector alignment in adolescent behavioral health: a study protocol
Authors: Walker Sarah Cusworth , Ahrens Kym R. , Owens Mandy D. , Parnes McKenna , Langley Joe , Ackerley Christine , Purtle Jonathan , Saldana Lisa , Aarons Gregory A. , Hogue Aaron , Palinkas Lawrence A. 
Published: May 2024

Abstract
Background
Policymaking is quickly gaining focus in the field of implementation science as a potential opportunity for aligning cross-sector systems and introducing incentives to promote population health, including substance use disorders (SUD) and their prevention in adolescents. Policymakers are seen as holding the necessary levers for realigning service infrastructure to more rapidly and effectively address adolescent behavioral health across the continuum of need (prevention through crisis care, mental health, and SUD) and in multiple locations (schools, primary care, community settings). The difficulty of aligning policy intent, policy design, and successful policy implementation is a well-known challenge in the broader public policy and public administration literature that also affects local behavioral health policymaking. This study will examine a blended approach of coproduction and codesign (i.e., Policy Codesign), iteratively developed over multiple years to address problems in policy formation that often lead to poor implementation outcomes. The current study evaluates this scalable approach using reproducible measures to grow the knowledge base in this field of study.

Methods
This is a single-arm, longitudinal, staggered implementation study to examine the acceptability and short-term impacts of Policy Codesign in resolving critical challenges in behavioral health policy formation. The aims are to (1) examine the acceptability, feasibility, and reach of Policy Codesign within two geographically distinct counties in Washington state, USA; (2) examine the impact of Policy Codesign on multisector policy development within these counties using social network analysis; and (3) assess the perceived replicability of Policy Codesign among leaders and other staff of policy-oriented state behavioral health intermediary organizations across the USA.

Discussion
This study will assess the feasibility of a specific approach to collaborative policy development, Policy Codesign, in two diverse regions. Results will inform a subsequent multi-state study measuring the impact and effectiveness of this approach for achieving multi-sector and evidence informed policy development in adolescent SUD prevention and treatment.
Design and rationale of the Botswana Smoking Abstinence Reinforcement Trial: a protocol for a stepped-wedge cluster randomized trial
Authors: Bada Florence , Mansfield Megan E. , Okui Lillian , Montebatsi Milton , DiClemente Carlo , Tapera Roy , Ikgopoleng Kaizer , Mokonopi Selebaleng , Magidson Jessica F. , Onukwugha Eberechukwu , Ndwapi Ndwapi , Himelhoch Seth , Mbongwe Bontle , Charurat Man 
Published: May 2024

Abstract
Background
With expanded and sustained availability of HIV treatment resulting in substantial improvements in life expectancy, the need to address modifiable risk factors associated with leading causes of death among people living with HIV/AIDS (PLWH), such as tobacco smoking, has increased. Tobacco use is highly prevalent among PLWH, especially in southern Africa, where HIV is heavily concentrated, and many people who smoke would like to quit but are unable to do so without assistance. SBIRT (Screening, Brief Intervention and Referral to Treatment) is a well-established evidence-based approach successful at supporting smoking cessation in a variety of settings. Varenicline is efficacious in supporting smoking cessation. We intend to assess the effectiveness of SBIRT and varenicline on smoking cessation among PLWH in Botswana and the effectiveness of our implementation.

Methods
BSMART (Botswana Smoking Abstinence Reinforcement Trial) is a stepped-wedge, cluster randomized, hybrid Type 2 effectiveness-implementation study guided by the RE-AIM framework, to evaluate the effectiveness and implementation of an SBIRT intervention consisting of the 5As compared to an enhanced standard of care. SBIRT will be delivered by trained lay health workers (LHWs), followed by referral to treatment with varenicline prescribed and monitored by trained nurse prescribers in a network of outpatient HIV care facilities. Seven hundred and fifty people living with HIV who smoke daily and have been receiving HIV care and treatment at one of 15 health facilities will be recruited if they are up to 18 years of age and willing to provide informed consent to participate in the study.

Discussion
BSMART tests a scalable approach to achieve and sustain smoking abstinence implemented in a sustainable way. Integrating an evidence-based approach such as SBIRT, into an HIV care system presents an important opportunity to establish and evaluate a modifiable cancer prevention strategy in a middle-income country (MIC) setting where both LHW and non-physician clinicians are widely used. The findings, including the preliminary cost-effectiveness, will provide evidence to guide the Botswanan government and similar countries as they strive to provide affordable smoking cessation support at scale.

Clinical trial registration
NCT05694637 Registered on 7 December 2022 on clinicaltrials.gov, https://clinicaltrials.gov/search?locStr=Botswana&country=Botswana&cond=Smoking%20Cessation&intr=SBIRT
Impact of early physiotherapy intervention in managing homonymous hemianopia due to posterior cerebral artery infarct—a case report
Authors: Abhinandan Abhishek , Chakraverty Sneha , Soumyashree Sonali , Bawiskar Dushyant 
Published: May 2024

AbstractHomonymous hemianopia field loss can develop as a result of injury to any part of the retro chiasmal visual pathway and is frequently fatal for subjects. The most common cause of homonymous hemianopia in older persons is ischemic infarction of the occipital lobe and its causes are multifactorial, frequently providing a diagnostic challenge to the clinician and signaling the necessity for a thorough systemic health review. Hemianopia is a loss of half of the visual field in each eye in which the inner or nasal half of one eye and the outer or temporal half of the other eye is affected. We report a case of a 72-year-old male subject who visited our department with complaints of weakness on the right side with difficulty seeing on the right side for 3 days. After undergoing various investigations, it was found that there is an acute infarct in the posterior cerebral artery territory supplying the left medial temporal lobe, medial occipital lobe, left thalamus, and splenium of the corpus callosum. After a physiotherapeutic examination provisionally, he was diagnosed with right hemiparesis and homonymous hemianopia, and thus, we administered an early physical therapy intervention which was found to be effective.
Analysis of the influence of water qualities on the strength of concrete
Authors: Mbuh Kuma Moses , Nsahlai Nyuykongi Leonard , Penka Bertrand Jule , Fru Chi Pride 
Published: May 2024

AbstractConcrete is commonly employed in construction for its tremendous compressive strength, despite its low tensile strength. This study aimed at analyzing the strength of concrete when mixed with water of varying qualities. Before concrete is formulated, tests are done on the aggregates to ascertain the right proportions but not on water used. Dreux-Gorrise concrete formulation method was employed. CAMWATER (tap water), rain water and water from a free-flowing river was used to cast concrete samples after which it was crushed to obtain 7 and 28 day resistances. The water qualities varied were pH and hardness. Hydrochloric acid and sodium hydroxide were used to vary the pH of water. Results showed an increase in concrete strength as a function of increase in water pH. Water with a high pH resulted in concrete with an appreciable strength value while acidic water resulted in very low strength values. The usage of hard water for mixing concrete resulted in a strength value lower than with soft water. Conclusively, water quality has an effect on the strength of concrete. Therefore, it is advisable to use water with a high pH value for mixing concrete, preferring rainwater over tap water when mixing concrete due to hardness of water.
Pitfalls in the Diagnostic Evaluation of Pheochromocytomas
Authors: Fagundes Gustavo F C , Almeida Madson Q 
Published: May 2024

Abstract
Pheochromocytomas and paragangliomas (PPGLs), rare neuroendocrine tumors arising from chromaffin cells, present a significant diagnostic challenge due to their clinical rarity and polymorphic symptomatology. The clinical cases demonstrate the importance of an integrated approach that combines clinical assessment, biochemical testing, and imaging to distinguish PPGLs from mimicking conditions, such as obstructive sleep apnea and interfering medication effects, which can lead to false-positive biochemical results. Although a rare condition, false-negative metanephrine levels can occur in pheochromocytomas, but imaging findings can give some clues and increase suspicion for a pheochromocytoma diagnosis. This expert endocrine consult underscores the critical role of evaluating preanalytical conditions and pretest probability in the biochemical diagnosis of PPGLs. Moreover, a careful differentiation of PPGLs from similar conditions and careful selection and interpretation of diagnostic tests, with focus on understanding and reducing false positives to enhance diagnostic accuracy and patient outcomes, is crucial.
A Scoping Review of Focused Ultrasound Enhanced Drug Delivery for Across the Blood–Brain Barrier for Brain Tumors
Authors: Young Christopher M. , Viña-González Ariel , de Toledo Aguiar Rodrigo Salmeron , Kalman Cheyenne , Pilitsis Julie G. , Martin-Lopez Laura I. , Mahani Tanmay , Pineda-Pardo José A. 
Published: May 2024

BACKGROUND AND OBJECTIVES:
Previous mechanisms of opening the blood–brain barrier (BBB) created a hypertonic environment. Focused ultrasound (FUS) has recently been introduced as a means of controlled BBB opening. Here, we performed a scoping review to assess the advances in drug delivery across the BBB for treatment of brain tumors to identify advances and literature gaps.

METHODS:
A review of current literature was conducted through a MEDLINE search inclusive of articles on FUS, BBB, and brain tumor barrier, including human, modeling, and animal studies written in English. Using the Rayyan platform, 2 reviewers (J.P and C.Y) identified 967 publications. 224 were chosen to review after a title screen. Ultimately 98 were reviewed. The scoping review was designed to address the following questions: (1) What FUS technology improvements have been made to augment drug delivery for brain tumors? (2) What drug delivery improvements have occurred to ensure better uptake in the target tissue for brain tumors?

RESULTS:
Microbubbles (MB) with FUS are used for BBB opening (BBBO) through cavitation to increase its permeability. Drug delivery into the central nervous system can be combined with MB to enhance transport of therapeutic agents to target brain tissue resulting in suppression of tumor growth and prolonging survival rate, as well as reducing systemic toxicity and degradation rate. There is accumulating evidence demonstrating that drug delivery through BBBO with FUS-MB improves drug concentrations and provides a better impact on tumor growth and survival rates, compared with drug-only treatments.

CONCLUSION:
Here, we review the role of FUS in BBBO. Identified gaps in the literature include impact of tumor microenvironment and extracellular space, improved understanding and control of MB and drug delivery, further work on ideal pharmacologics for delivery, and clinical use.
Αναπαραστάσεις Εκπαιδευτικών Δευτεροβάθμιας Εκπαίδευσης για τη Διγλωσσία των Προσφύγων Μαθητών/τριών
Authors: Δεληγιάννη Αικατερίνη , Πίτσου Χαρίκλεια , Χριστοδούλου Μιχάλης 
Published: May 2024

Η κατανόηση και αξιοποίηση από τους/τις εκπαιδευτικούς της σχέσης διγλωσσίας και μάθησης επιτρέπει τη διαμόρφωση υποστηρικτικού μαθησιακού πλαισίου για την εκμάθηση της γλώσσας του σχολείου και τη διδασκαλία των μαθημάτων μέσω της Ελληνικής ως δεύτερης γλώσσας. Σκοπός της παρούσας εργασίας ήταν να διερευνήσει τις αναπαραστάσεις εκπαιδευτικών Γυμνασίων για τη διγλωσσία των προσφύγων μαθητών/τριών τους, με έμφαση στην ανάπτυξη της ακαδημαϊκής γλώσσας του σχολείου. Το δείγμα της έρευνας αποτέλεσαν 153 εκπαιδευτικοί όλων των ειδικοτήτων, που υπηρετούν σε Γυμνάσια της επικράτειας, όπου λειτουργούν Τάξεις Υποδοχής (ΤΥ), και διδάσκουν σε πρόσφυγες μαθητές/τριες. Από τα αποτελέσματα της έρευνας προέκυψε ότι οι εκπαιδευτικοί, παρά την ευρεία θεώρηση του περιεχομένου της διγλωσσίας, δεν αντιλαμβάνονται τους πρόσφυγες μαθητές/τριες ως δίγλωσσα υποκείμενα. Μολονότι οι δυσκολίες εκμάθησης της ελληνικής εντοπίζονται στην κατανόηση αφηρημένων εννοιών και τις δεξιότητες του γραπτού λόγου, η πλειονότητα των εκπαιδευτικών υιοθετεί την αρχή της μέγιστης έκθεσης στη γλώσσα στόχο και προκρίνει ως ενδεδειγμένη πρακτική την αποκλειστική χρήση της ελληνικής στον χώρο του σχολείου. Ωστόσο, αρκετοί εκπαιδευτικοί εφαρμόζουν διδακτικές πρακτικές και παιδαγωγικές μεθόδους που υποστηρίζουν την ακαδημαϊκή ανάπτυξη των προσφύγων μαθητών/τριών.
Υποστηρικτικοί θεσμοί για την εκπαίδευση των παιδιών των προσφύγων
Authors: Διακογεωργίου Αρχοντούλα 
Published: May 2024

Το ελληνικό εκπαιδευτικό σύστημα καλείται να προσαρμοστεί στις μεγάλες αλλαγές τις οποίες έχει επιφέρει το προσφυγικό κύμα κατά τα τελευταία χρόνια στην κοινωνική σύνθεση του πληθυσμού. Στο χώρο του σχολείου υλοποιούνται αλλαγές, καθώς η εκπαίδευση αποτελεί το βασικό πυλώνα της κοινωνικής συνοχής. Βασικός στόχος της εκπαίδευσης είναι η ένταξη των παιδιών με προσφυγικό υπόβαθρο στην κοινωνική, οικονομική και πολιτιστική ζωή της χώρας και όχι η αφομοίωσή τους. Οι κοινωνικές διαφορές απειλούν τη συνοχή του κοινωνικού ιστού της χώρας υποδοχής και αυξάνει τις δυσκολίες στη ζωή των προσφύγων. Στο παρόν άρθρο θα παρουσιάσουμε τους θεσμούς για την υποστήριξη των μαθητών- προσφύγων στο σχολείο με ιδιαίτερες αναφορές στις Τάξεις Υποδοχής και στις Δομές Υποδοχής και Εκπαίδευσης των προσφύγων. Επίσης θα αναφέρουμε τα ζητήματα τα οποία προκύπτουν στο πλαίσιο της λειτουργίας των υποστηρικτικών θεσμών και θα διατυπώσουμε προτάσεις για το διδακτικό υλικό και το διδακτικό προσωπικό το οποίο στελεχώνει Τάξεις Υποδοχής και στις Δομές Υποδοχής και Εκπαίδευσης των προσφύγων.
Sukcesja prawa do zastosowania się do interpretacji indywidualnej przepisów prawa podatkowego i ochrony z niej wynikającej
Authors: Szczepańska Karolina 
Published: May 2024

Niniejszy artykuł dotyczy problemu sukcesji prawa do zastosowania się do interpretacji indywidualnej oraz ochrony przysługującej na jej podstawie. Możliwość skorzystania następcy prawnego z interpretacji oraz bezpieczeństwo i gwarancja ochrony, przysługujące na mocy art. 14k - 14m o.p. to zagadnienie, które mimo licznych wyroków, wzbudza wiele kontrowersji. Zarówno w orzecznictwie jak i wśród przedstawicieli doktryny występują przeciwstawne stanowiska w kwestii tego jak należy interpretować wskazane w art. 93 § 1 o.p. wstąpienie „we wszelkie" przewidziane w przepisach prawa podatkowego prawa i obowiązki każdej z łączących się osób lub spółek. Rozbieżności i ograniczenia w tym zakresie utrudniają podatnikom ułożenie i zaplanowanie w sposób bezpieczny znaczących podatkowo przedsięwzięć, zwłaszcza dotyczących prowadzonej działalności gospodarczej. W artykule poza zasadami sukcesji praw wynikających z interpretacji indywidualnej przedstawiono także podstawowe informacje na jej temat oraz ogólne rozważania dotyczące charakteru interpretacji.
Incentivizing Organ Donation Under Different Priority Rules: The Role of Information
Authors: Li Mengling , Riyanto Yohanes E. 
Published: May 2024

This paper examines the incentive to register for deceased organ donation under alternative organ allocation priority rules, which may prioritize registered donors and/or patients with higher valuations for organ transplantation. Specifically, the donor priority rule grants higher priority on the organ waiting list to those who have previously registered as donors. The dual-incentive priority rules allocate organs based on donor status, followed by individual valuations within the same donor status, or vice versa. Both theoretical and experimental results suggest that the efficacy of the donor priority rule and the dual-incentive priority rules critically depends on the information environment. When organ transplantation valuations are unobservable prior to making donation decisions, the hybrid dual-incentive rules generate higher donation rates. In contrast, if valuations are observable, the dual-incentive priority rules create unbalanced incentives between high- and low-value agents, potentially undermining the efficacy of the hybrid dual-incentive rules in increasing overall donation rates. This paper was accepted by Marie Claire Villeval, behavioral economics and decision analysis. Funding: This research is supported by the National Natural Science Foundation of China [Grants 72173103, 72373127, and 71988101], the Singapore Ministry of Education (MOE) Academic Research Fund Tier 1 [RG57/20], and the Open Foundation of Key Laboratory of Interdisciplinary Research of Computation and Economics (Shanghai University of Finance and Economics), Ministry of Education of China. Supplemental Material: The online appendices and data files are available at https://doi.org/10.1287/mnsc.2022.01530 .
Bidder-Specific Synergies and the Evolution of Acquirer Returns
Authors: Dessaint Olivier , Eckbo B. Espen , Golubov Andrey 
Published: May 2024

Largely constant average acquirer returns over the past four decades mask fundamental changes in the takeover market. Controlling for bidder composition, the common component of acquirer returns has increased by five percentage points relative to the 1980s. Offsetting this increase, the average bidder-specific component has declined. We propose a theory of bidder-specific synergies to help interpret these opposing trends. In our theory and in the data, acquirer returns increase with the extent to which synergies are unique to that bidder. The composition effect reflects bidder uniqueness. Overall, the evidence is consistent with rising merger synergies that have become less bidder specific. This paper was accepted by Victoria Ivashina, finance. Funding: A. Golubov acknowledges financial support from the Bank of Canada [Governor’s Award]. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.02208 .
Is Blockholder Diversity Detrimental?
Authors: Schwartz-Ziv Miriam , Volkova Ekaterina 
Published: May 2024

We find that, overall, blockholder diversity, i.e., the firm shareholder base including several different types of blocks, is detrimental to firm performance. We show that lagged disclosure, on exogenous predetermined dates, that reveals an increase in block diversity is followed by a negative market reaction. Firms held by heterogeneous blockholders consistently perform worse than firms held by homogeneous blockholders. Block diversity is particularly detrimental when uncertainty is high. Disagreement among shareholders (e.g., as reflected in the frequency of lawsuits being filed) increases when the blockholder base is diverse. We make our blockholder data set public for the benefit of other researchers. This paper was accepted by Victoria Ivashina, finance. Funding: This work was supported by the Israel Science Foundation [Grant 264/20], the Faculty of Business and Economics, University of Melbourne [Grant ECR00009FNL], and the Accounting and Finance Association of Australia and New Zealand [Grant 2020-033]. Supplemental Material: The online appendices and data files are available at https://doi.org/10.1287/mnsc.2023.00528 .
MULLER-WEISS DISEASE: PROPOSED CLASSIFICATION AND TREATMENT ALGORITHM
Authors: McKenna R. , Wong J. , Tucker A. 
Published: May 2024

Muller-Weiss disease is an uncommon condition with unclear etiology and no gold standard treatment. The question arises; which joints to fuse? Although no consensuses prevail, one must postulate fusion should include those affected. Consequently, to establish an algorithm for its surgical management we set out to study clinical and radiographic features with use of SPECT-CT and a literature review.57 consecutive feet presenting with Muller-Weiss disease analysed; 15 men, 25 women, age 22–84. Condition bilateral in 17, left side 16, right in 7 patients. Specific history and examination by senior author. Radiographic series and SPECT-CT obtained with surgery performed on significantly symptomatic feet. Measurements of Meary-Tomeno angles, anteroposterior thickness of navicular at the midpoint of each naviculo-cuneiform, alongside the medial extrusion distance and percentage of compression in each case performed. Poor correlation between Meary's angle and 1) degree of compression at naviculo-cuneiform joints, 2) degree of extrusion 3) compression vs extrusion using R2 coefficient of determination (invalidating Maceira et al. classification). In unilateral cases, extrusion significantly greater on affected side 94.7% (P< 0.001 Fisher exact test). Degree of extrusion significantly greater in bilateral than unilateral cases (p=0.004 unpaired T test). Valgus hindfoot and Meary's negative most common pattern with no correlation between heel alignment and Meary's R2 = 0.003. SPECT-CT useful to determine subtalar involvement in ‘stage 2 disease.’Following review of cases and published literature we propose the following classification for Muller-Weiss disease with treatment algorithm. 3 Stage delineation; Stage 1 (Normal hindfoot alignment); 1A. Talonavicular disease only - Isolated Talonavicular arthrodesis 1B. Talonavicular + Subtalar; double medial or triple arthrodesis. Stage 2. Talonavicular + Naviculocuneiform; 2A. Adequate bone stock - Talo-naviculo-cuneiform arthrodesis, 2B. Inadequate bone stock +- subtalar disease; Talo-naviculo-cuneiform arthrodesis with tricortical bone graft (Mayich). Stage 3; Asymmetric ankle varus. Pantalar arthrodesis Double/triple/TNC/TAR arthrodesis with hindfoot re-alignment.
The challenges facing educational institutions in meeting the educational needs of students
Authors: Banaszak Artur 
Published: May 2024

The right to education is one of the basic human rights guaranteed by international and many national regulations. According to Article 26 of the Universal Declaration of Human Rights and other international law regulations in the national laws of many different countries, education is one of the fundamental human rights. Therefore, the biggest and most important challenge related to education is access to education for everyone it means taking actions to make this right a reality and work for everyone, everywhere. The aim of these studies is to present the most important challenges that educational institutions face in the process of meeting the educational needs of students.
Relationships in the family of a child with autism
Authors: Miłek Katarzyna 
Published: May 2024

The article is an analysis of psychosocial relations in the family of a child with autism. The family of a child with autism goes through the stages of re-evaluation of expectations towards the child, the relationships between siblings and parents change. They intensify periods of emotional uncertainty, crisis situations, seeking confirmation or rejection of a diagnosis. The period of learning to live with one’s and the whole family’s problem determines the effectiveness of the search, the results of therapy, the quality of relationships in the family and the immediate environment, which is necessary in the everyday-unusual dimension of the child’s development. Knowledge of the subject and high empathy of educators working with children with autism (and parents of children functioning correctly in terms of psychosocial) is the key to supporting their development and supporting the development of family relationships.