bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Influencing Child Welfare Clinic Attendance in a Periurban Community: A Descriptive Cross‐Sectional Study
Authors: Torgbor-Anaman Judith A. , Johnson Beatrice B. , Tackie Vivian , Konlan Kennedy Diema 
Published: February 2025

Introduction: Child welfare clinics (CWCs) provide a platform for health practitioners to communicate with caregivers and provide growth monitoring, childhood immunization, health education, and other health promotion services. This study described factors influencing caregivers’ attendance at CWC in the Godokpe Community in Ho.Methodology: This is a cross‐sectional study that used questionnaires for data collection among 403 caregivers having children under 5 years. The respondents were selected using convenience sampling techniques. Data were analyzed using SPSS version 25 to generate descriptive statistics and to test associations between independent variables and CWC attendance. A p value ≤ 0.05 was statistically significant.Results: The findings indicated that 80.4% of the caregivers had a high level of knowledge about CWC. The factors that influenced continued CWC attendance were encouragement by nurses (94.3%), the nurses being empathetic (93.8%), nurses showing a positive attitude toward caregivers (91.8%), the perception that attending CWC is an ideal childcare process (91.6%), having less waiting time (90.8%), having knowledge on child care practices (90.6%), having an appropriate timing for CWC services (90.1%), perception that there is the provision of adequate care for sick children at CWC (89.8%), perception that CWC is a needful care practice for children (82.4%), and acknowledging CWC as a requirement stated in the child welfare card (82.1%). Also, caregivers (79.0%) attended CWC sessions regularly. The adjusted odds ratio showed that caregivers without formal education (AOR = 0.10, 95% CI: 0.02–0.37, p value = 0.001), having primary education (AOR = 0.13, 95% CI: 0.04–0.37, p value < 0.001), and having secondary education (AOR = 0.34, 95% CI: 0.12–0.91, p value = 0.036) predicted CWC attendance compared to those with tertiary education. Experience at CWC (AOR = 2.52, 95% CI: 1.20–5.81, p value = 0.021) and having children between 0 and 11 months (AOR = 3.16, 95% CI: 1.50–6.89, p value = 0.003) predicted CWC attendance.Conclusion: We identified various factors (sociodemographic and knowledge/perception) influencing CWC attendance. Healthcare providers must institute interventions targeting parents having lower education status and having children older than 11 months for continued CWC attendance even after the completion of routine immunizations. This may include continued home visits to provide CWC care to children less than 5 years old.
Calvin and the Age of the Earth
Authors: Adhinarta Yuzo , Santoso Agus , Putrawan Bobby Kurnia 
Published: February 2025

Abstract
This article presents three assumptions that underlie the claim that Calvin would support or adhere to the young earth view if he were alive in the twentieth or twenty first century. The argument for the claim that Calvin provides support for the twentieth-century young earth view is untenable. Calvin does not make assertions that can be appealed to as substantial support for the young earth view. To support this position we present three counterarguments to the three underlying assumptions we briefly presented above, regarding Calvin’s own assertions concerning the six days of creation, his accommodation theory, and his commonality with his contemporaries. Although Calvin might have held the view of six literal days, as he was evidently opposing the instantaneous creation theory of his time, he does not provide as much support for the twentieth-century literal six days view as young earth creationists might expect. Attempting to align Calvin’s view of the creation days with the twentieth-century debate is not only unwarranted but also does not do justice to Calvin.
Developments in analytical techniques for mycotoxin determination: an update for 2023-24
Authors: Tittlemier S.A. , Cramer B. , DeRosa M.C. , Dzuman Z. , Kodikara C. , Malone R. , Maragos C. , Suman M. , Sumarah M.W. 
Published: February 2025

Abstract
This review summarises developments published in the period from mid-2023 to mid-2024 on the quantitative and qualitative determination of mycotoxins in a various matrices. Important developments in all aspects of mycotoxin analysis, from sampling and quality assurance/quality control of analytical results, to the various detection and quantitation technologies ranging from biosensors to comprehensive instrumental methods are presented and discussed. This non-exhaustive summary and associated discussion covers such technology as chromatography with targeted or non-targeted high resolution mass spectrometry, detection other than mass spectrometry such as fluorescence or diode array detection, biosensors, assays using alternatives to antibodies, as well as methods using predictive modelling and incorporating machine learning. This collaborative critical review intends to guide readers to relevant research by briefly presenting the most important developments in mycotoxin determination published in the past year. This review also relays limitations of the presented methodologies, in order to provide a thorough assessment of the analytical developments.
Nutrient-enriched live lobster cockroach, Nauphoeta cinerea, enhances growth and pigmentation of the pearl arowana, Scleropages jardini
Authors: Ng W.K. , Koay K.T. , Lee C.Y. 
Published: February 2025

Abstract
This is the first report on the use of live cockroaches as feed for farmed arowanas. Firstly, the nymphal development period, reproductive potential, longevity and nutrient profiles of the various development stages of the lobster cockroach, Nauphoeta cinerea, were determined. The fecundity of each female cockroach averaged 82.9 nymphs. An increase in body crude protein and lipid levels was observed as nymphs metamorphosised into later instars. The nutrient content of the adult stage was different from the nymphal stages with distinct differences evident between sexes. Secondly, in the feeding trial of pearl arowana, Scleropages jardini, three groups of live cockroaches were used; adult males with low lipid and high protein levels (3% and 30.1%, respectively; A-LLHP, control group), adult males with mid-level lipid and high protein levels (6.1% and 29.7%, respectively; A-MLHP) and late nymphs with high lipid and lower protein levels (10.3% and 22.9%, respectively; N-HLLP). Each group of cockroaches was fed to eight replicate individually-housed fish once daily for 12 weeks. A-LLHP and N-HLLP cockroaches were fed a commercial rat feed, whereas A-MLHP cockroaches were fed a specially formulated feed with added astaxanthin (80 mg/kg) to produce nutrient-enriched cockroaches. Arowana growth was highest in the N-HLLP-fed group followed by A-MLHP and A-LLHP (). The best feed utilization efficiency was observed in the N-HLLP group. Intraperitoneal fat and muscle lipid content was significantly higher in fish fed the nymphs than those fed adult cockroaches. Scales of arowana fed A-MLHP cockroaches showed the highest melanophore and xanthophore counts. Xanthophores were not present in the scales of the N-HLLP group. Late nymphal stages are optimal for growth enhancement and adult cockroaches for pigmentation of fish. This study showed that live cockroaches can be nutrient-enriched to enhance arowana growth and pigmentation.
Edible ants: exploring species and their utilisation
Authors: van Huis A. 
Published: February 2025

Abstract
Various ant species and their products serve as food sources across different regions of the world. Notable examples include Carebara spp. from Africa, Atta spp. and Liometopum sp. from Latin America, Formica rufa from Europe, and Oecophylla spp. from Asia. In addition to being consumed directly, ants are used as flavouring agents and incorporated into a variety of culinary recipes. Humans also harvest cereals and honey gathered by ants.
A Conceptual Analysis of Technology Usage and Work–Family Interface Among Millennials in India
Authors: Dash Sasmita 
Published: February 2025

Executive Summary Technology usage and its derogatory impact on employees give the impression of a new pandemic globally. In addition, having employees from multiple generations in the same workforce has turned the situation even more complex. The available literature on generational cohorts has predominantly looked at the lives in the Western world. However, Dr Twenge highlighted that the generational psyche has been influenced by the concurrent social–economic and cultural changes that took place during the childhood of that generation. Undoubtedly, India as a society has gone through a significant shift in this context since the 1980s, different from the changes happening in the Western world at the same time. In this article, I have tried to highlight these changes and connect them with the work–family ideologies and technology usage of the current dominant generation, the ‘millennial’ in the workforce. Different genders might have developed differing work–family values even when belonging to the same generational cohort. This article gives a well-developed mediation and moderation model to understand how different generational cohorts would experience the work–family conflict mediated by perceived digital overuse (PDO), which is an outcome of technology usage mostly ‘smartphones and internet’. Gender has been highlighted as a crucial moderator in the model, like female employees might be more ready to take advantage of this phenomenon of technology usage than male employees. The efforts recovery theory ( Meijman & Mulder, 1998 ) and the conservation of resources theory ( Hobfoll, 1989 ) have contributed to this model formulation. This article will be very helpful in comprehending the work and non-work needs of different generational cohorts, mostly the dominant cohort ‘millennial’, along with a gender component in it, in deciding the work–family policy formulation.
The Effect of Intermittent Theta Burst Stimulation for Post-Stroke Lower Limb Motor Recovery: Systematic Review and Meta-Analysis
Authors: Su Xinyi , Zheng Beisi , Huang Haiping , Chen Shishi , Cao Manting , Chen Jianer 
Published: February 2025

Background Intermittent theta burst stimulation (iTBS) appears to be a potential intervention for enhancing motor recovery in post-stroke. However, the optimal parameters of iTBS protocol for lower limb dysfunction is ambiguous. Objective To evaluate the efficacy of iTBS in treating lower limb motor impairment after stroke and to explore the optimal stimulation parameters. Methods Relevant randomized controlled trials (RCTs) were retrieved from seven databases from their inception to May 2024. We defined primary outcomes as Fugl-Meyer Assessment for Lower Extremity (FMA-LE) and Berg Balance Scale (BBS). Subgroup analyses included stroke stage, stimulation sites, dosages and treatment sessions. Results The study results indicated that compared with the sham iTBS group, the iTBS group showed a significant improvement in lower limb motor recovery, balance, gait and activity of daily living (ADL). No significant effect was found in the Motor Evoked Potential amplitude. Subgroup analysis demonstrated that cerebellar iTBS had a therapeutic effect on subacute stroke patients. Furthermore, administrating 1200 pulses per session for a minimum of 15 sessions of iTBS intervention could significantly improve the balance and ADL performance. Conclusion iTBS could enhance lower limb motor function, improving the quality of life in subacute stroke patients with relatively high safety. Systematic review registration: CRD42024549603
Developing a Prognostic Model for Intrahepatic Cholangiocarcinoma Patients With Elevated Preoperative Carbohydrate Antigen 19-9 Levels: Volume-Adjusted CA19-9 (VACA) as a Novel Biomarker
Authors: Liu Bo , Wang Sheng , Wen Tao , Qiu Haizhou , Xiang Lei , Huang Zuotian , Wu Hong , Li Dewei , Li Hui 
Published: February 2025

Purpose The predictive sensitivity of carbohydrate antigen 19-9 (CA19-9) in assessing the prognosis of intrahepatic cholangiocarcinoma (ICC) remains inadequate. Integrating CA19-9 with tumor volume offers a potentially viable strategy for improving prognostic accuracy. This study aimed to develop a prognostic model utilizing volume-adjusted CA19-9 (VACA) for ICC patients. Patients and Methods A retrospective analysis was conducted on data from 436 ICC patients. These patients from two centers were divided into the training (n = 291, Center 1) and validation (n = 145, Center 2) cohorts. Using the training cohort, univariate and multivariable Cox regression analyses were employed to identify clinicopathological characteristics significantly associated with overall survival (OS) and recurrence-free survival (RFS), which enabled the construction of prognostic nomograms both with and without VACA. The nomograms’ discriminatory and calibration abilities were assessed using receiver operating characteristic (ROC) curves, decision curve analysis (DCA) curves, and calibration curves, applying both training and validation cohorts. Results VACA emerged as an independent variable that significantly correlated with prognosis. The nomogram incorporating VACA demonstrated superior accuracy in predicting OS and RFS rates compared to the model without VACA. In the validation cohort, the nomogram with VACA yielded area under the ROC curve (AUC) values of 0.695 (95% CI = 0.597∼0.793) and 0.666 (95% CI = 0.559∼0.773) (1- year), 0.662 (95% CI = 0.518∼0.806) and 0.651 (95% CI = 0.446∼0.857) (3- years), and 0.701 (95% CI = 0.486∼0.916) and 0.703 (95% CI = 0.428∼0.978) (5- years) for OS and RFS, respectively, along with improved calibration and DCA curves. Conclusions VACA, formed by integrating tumor volume with CA19-9, exhibits promising prognostic capabilities. The nomogram incorporating data from two centers and utilizing VACA demonstrates robust prognostic performance and holds clinical utility. Condensed abstract Combining CA19-9 with tumor volume presents a potentially viable strategy for improving prognostic accuracy. The nomogram incorporating VACA demonstrates robust prognostic performance and holds clinical utility.
Access to healthcare for people with intellectual disability: a scoping review
Authors: Barrington Maryann , Fisher Karen R. , Harris-Roxas Ben , Spooner Catherine , Trollor Julian N. , Weise Janelle 
Published: February 2025

Aims: People with intellectual disability experience stark health inequalities, often because of poor access to mainstream healthcare. This scoping review aimed to identify factors that influence access to healthcare for people with intellectual disability using Levesque and colleagues’ comprehensive framework of healthcare access. Method: This review followed Joanna Briggs Institute guidelines. Articles were identified and retrieved from CINAHL, PsycINFO, PubMed and EMBASE. Two reviewers completed abstract and full-text screening, addressing any conflicts at each stage. Data was extracted and coded deductively, according to the supply (healthcare provider) and demand (healthcare seeker) dimensions of Levesque and colleagues’ framework. Results: Following search and screening, 66 references were included for review. Barriers to healthcare were more frequently identified in the literature compared to facilitators, with most information relating to supply-side dimensions. Barriers were related to inaccessible health information, low health literacy, stigma and discrimination by healthcare providers, and lack of organisational support, training and resourcing in both healthcare and support sectors. Facilitators often involved specialist workforces, strong interpersonal skills among healthcare providers, and advocacy from supporters. Importantly, findings indicated that both sociohistorical processes and support networks are necessary to understanding access experiences for people with intellectual disability. Conclusions: Greater efforts are required internationally to ensure the health rights of people with intellectual disability, to eliminate discrimination, and provide the support and resources necessary for all stakeholders to facilitate healthcare access. Models of healthcare access for people with intellectual disability should consider both the role of supporters and the sociohistorical context within which healthcare access occurs.
Early Phase Multiple Sclerosis Patients Present Substantial Deficits in Physical-, Cognitive-, and Patient-reported Outcomes Compared to Matched Healthy Controls
Authors: Thrue Cecilie , Hvid Lars G. , Diechmann Mette , Gaemelke Tobias , Stenager Egon , Dalgas Ulrik , Riemenschneider Morten 
Published: February 2025

Background Early identification of potential deficits is of utmost importance as early diagnosis and early treatment has been shown to be crucial to reduce disease activity and disease impact—leading to the notion of “Time matters” in multiple sclerosis (MS). Objective The aim of the present study was to compare physical-, cognitive-, and patient-reported outcomes in early phase MS patients with matched healthy controls (HC). Methods This cross-sectional study included 84 patients early in the disease course of MS (≤2 years from diagnosis) and 84 age- and sex-matched HC. All participants underwent a comprehensive test battery including physical-, cognitive-, and patient-reported outcomes. Results Relative deficits for patients with MS compared to HC corresponded to 7% to 35% in walking capacity (Timed 25-Foot Walk Test, 6 Spot Step Test, 6 Minute Walk Test), 5% for upper limb function (9 Hole Peg Test), 27% for aerobic capacity (maximal oxygen uptake), 17% to 38% for physical activity level (Baecke Sport Index and accelerometer counts/minute), 68% for fatigability (Walking Fatigability Index), 150% for fatigue (Modified Fatigue Impact Scale), 4% to 20% for cognitive function (Symbol Digit Modalities Test, Paced Auditory Serial Addition Test, and Selective Reminding Test), and lastly, 7% to 8% for quality of life (Short Form-36 health survey). Only the Symbol Digit Modalities Test and Selective Reminding Test Delayed did not differ between groups, statistically. Conclusion Early phase MS patients present substantial deficits in physical-, cognitive-, and patient-reported outcomes compared to HC. These early impairments highlight the importance of early initiatives aimed at preserving and/or building of reserve capacity.
Improving reliability of movement assessment in Parkinson's disease using computer vision-based automated severity estimation
Authors: Xu Jinyu , Xu Xin , Guo Xudong , Li Zezhi , Dong Boya , Qi Chen , Yang Chunhui , Zhou Dong , Wang Jiali , Song Lu , He Ping , Kong Shanshan , Zheng Shuchang , Fu Sichao , Xie Wei , Liu Xuan , Cao Ya , Liu Yilin , Qiu Yiqing , Zheng Zhiyuan , Yang Fei , Gan Jing , Wu Xi 
Published: February 2025

Background Clinical assessments of motor symptoms rely on observations and subjective judgments against standardized scales, leading to variability due to confounders. Improving inter-rater agreement is essential for effective disease management. Objective We developed an objective rating system for Parkinson's disease (PD) that integrates computer vision (CV) and machine learning to correct potential discrepancies among raters while providing the basis for model performance to gain professional acceptance. Methods A prospective PD cohort (n = 128) were recruited from multi-centers. Motor examination videos were recorded using an android tablet with CV-based software following the MDS-UPDRS Part-III instructions. Videos included facial, upper- and lower-limb movements, arising from a chair, standing, and walking. Fifteen certified clinicians were recruited from multi-centers. For each video, five clinicians were randomly selected to independently rate the severity of motor symptoms, validate the videos and movement variables (MovVars). Machine learning algorithms were applied for automated rating and feature importance analysis. Inter-rater agreement among human raters and the agreement between artificial intelligence (AI)-generated ratings and expert consensus were calculated. Results For all validated videos (n = 1024), AI-based ratings showed an average absolute accuracy of 69.63% and an average acceptable accuracy of 98.78% against the clinician consensus. The mean absolute error between the AI-based scores and clinician consensus was 0.32, outperforming the inter-rater variability (0.65), potentially due to the combined utilization of diverse MovVars. Conclusions The algorithm enabled accurate video-based evaluation of mild motor symptom severity. AI-assisted assessment improved the inter-rater agreement, demonstrating the practical value of CV-based tools in screening, diagnosing, and treating movement disorders.
Phenotyping the Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA)
Authors: Celis-Preciado Carlos , Leclerc Simon , Duval Martine , Cliche Dominic O. , Brazeau Lucie , Vézina Félix-Antoine , Dussault Marylène , Larivée Pierre , Lemaire-Paquette Samuel , Lévesque Simon , Lachapelle Philippe , Couillard Simon 
Published: February 2025

BackgroundAsthma attacks are heterogeneous. It is not known whether the response to oral corticosteroids (OCS) in acute asthma varies according to type-2 (T2) inflammatory biomarkers, blood eosinophil count (BEC) and exhaled nitric oxide (FeNO). We aim to explore the relationship between T2 biomarkers and response to OCS in acute asthma.MethodsWe conducted a longitudinal observational study of people experiencing an asthma attack evaluated before and after a 7-day OCS course. The primary outcome was post-bronchodilator (BD) FEV1change according to ordinal BEC-FeNO 3-group categories (T2-Low/Low, BEC <0.15×109 cells·L−1and FeNO <25 ppb; T2-High/High, BEC ≥0.30×109 cells·L−1and FeNO ≥35 ppb and T2-Mid, not meeting Low/Low-High/High criteria). A key secondary outcome was the Asthma Control Questionnaire (ACQ-5) change. Exploratory outcomes included OCS-attributable adverse events.ResultsFifty-three people were enrolled with 16 (30%) T2-Low/Low, 27 (51%) T2-Mid and 10 (19%) T2-High/High asthma attacks. Post-BD FEV1changes increased with combined BEC-FeNO elevation (p-for-interaction=0.007), peaking in the T2-High/High phenotype (0.390±0.512L, p-for-trend<0.0001). Conversely, T2-Low/Low attacked achieved nonsignificant FEV1changes (0.017±0.153L). In univariable and multivariable analyses, only ordinal BEC-FeNO stratification – not symptoms nor FEV1– was a predictor of subsequent post-BD FEV1improvement. All patients improved ACQ-5, numerically peaking in the T2-High/High phenotype (−1.58±0.60, p-for-trend=0.08). All groups experienced similar OCS-attributable adverse events, with n=33 (62%) participants reporting ≥1 event.ConclusionsWe found that objective improvement following OCS is confined to T2-High/High events. As in chronic asthma, greater T2 burden identifies a distinct clinical and therapeutic trajectory, whereas OCS-related adverse events are uniformly distributed.