bluuebunny/crossref_metadata_2025_split huggingface dataset:
Condensed benzopyrans. IV. Synthesis of some derivatives of 7H‐ and 9H‐pyrano[3,2‐E]indoles
Authors: Khan Misbahul Ain , De Brito Morley Maria Lúcia 
Published: April 2009

AbstractThe hydrazones derived from coumarin‐6‐ylhydrazine and ethyl 6‐hydrazinochromone‐2‐carboxylate undergo facile indolization to give 3H,7H‐pyrano[3,2‐e]indol‐7‐ones (IIIb‐IIIg) and ethyl 9‐oxo‐3H,9H‐pyrano[3,2‐e]indole‐7‐carboxylates (IVb‐IVd), respectively, in good yields. Compounds IVb‐IVd are derivatives of a new ring system.
Oxidation and acid‐catalyzed cyclization of aldehyde 2‐aminophenylhydrazones. Alternative syntheses for 1,2,4‐benzotriazines and benzimidazoles
Authors: Cerri Riccardo , Roido Alessandro , Sparatore Fabio 
Published: April 2009

AbstractAldehyde 2‐aminophenylhydrazones are easily oxidized by air to 3‐substituted 1,2,4‐benzotriazines. In two cases the intermediate 3,4‐dihydro‐1,2,4‐benzotriazines were isolated. In the absence of oxygen, acids catalyze the formation of 2‐substituted benzimidazoles with loss of ammonia. It is suggested that both reactions proceed via 1,2,3,4‐tetrahydro‐1,2,4‐benzotriazines (III), formed by addition of the amino group on the hydrazone double bond. Such cyclic forms (III) predominate over the open chain structures (II) in the cases of aliphatic and arylalkylaldehyde 2‐aminophenylhydrazones, as supported by nmr spectra, while benzaldehyde 2‐aminophenylhydrazone exists mainly or exclusively in the open chain form (II).
Sulfur nitride in organic chemistry. 6. Preparation of 3,4‐disubstituted 1,2,5‐thiadiazoles by the reaction of sulfur nitride with acetylenes
Authors: Mataka Shuntaro , Takahashi Kazufumi , Yamada Yukihiro , Tashiro Masashi 
Published: April 2009

AbstractThe reaction of sulfur nitride (1) with acetylenes (2a‐m) was carried out in refluxing toluene to give 1,2,5‐thiadiazoles (3a‐m) as a major product.
2‐Aminothiazole derivatives. II. Mass spectra of ethyl N‐(2‐thiazolyl)‐malonamates and ethyl 2‐thiazolylaminomethylenemalonates
Authors: Saint‐Ruf G. , Silou T. H. 
Published: April 2009

AbstractThe fragmentation pattern of the title compounds under electron impact are discussed. During fragmentation in the mass spectrometer, these compounds undergo a rare type of rearrangement involving a long distance transfer of hydrogen.
Friedel‐crafts acylalion of 3‐carboxymethylbenzo[B] thiophenes, LIS‐nmr and HOMO study of regioselectivity
Authors: Hannoun M. , Blazević A. , Kolbah D. , Sabljiéa A. , Trinajstić N. , Sega A. , Lisini A. , Kajfež F. , Šunjić V. 
Published: April 2009

Abstract3‐Carboxymethylbenzo[b] thiophenes give on benzoylation and acetylation, two pairs of isomers, 2/3 and 4/5, respectively. It is determined by the combined nmr spectroscopic analysis (360 MHz and calculated spectra, LIS‐nmr) and HOMO calculations of the electron densities on positively charged 1, that 2 and 4 are 4‐substituted, while 3 and 5 are 6‐substituted isomers.
Synthese du noyau dihydro‐5,6 s‐triazolo[2,3‐d] henzoxazepine‐1,4
Authors: Moskowitz H. , Mignot A. , Miocque M. 
Published: April 2009

AbstractUn nouveau système hétérocyclique, la méthylène‐5 éthylthio‐2 dihydro‐5,6 s‐triazolo [2,3‐d] henzoxazépine‐1,4, a été preparé par cyclisation du propynyloxyphenyltriazole correspondant. L'attaque nucléophile d'un azote triazolique sur la triple liaison conduit également à trois isornères et notamment à une s‐triazolo [3,2‐d] benzoxazocine.
A simple synthesis of 1‐phenothiazineethanolamines: Potential antimalarials
Authors: Pinto Ângelo C. , Da Silva Rosaly S. , Hollins Richard A. 
Published: April 2009

AbstractTwo routes for the synthesis of the 1‐phenothiazineethanolamine (4) starting from 1,2‐dioxo‐1,2‐dihydropyrrolo[3,2,1‐kl]phenothiazine are described.
The synthesis and photochemistry of 4‐amino‐3‐cyanopyrazole
Authors: Kagan Jacques , Melnick Bennett 
Published: April 2009

Abstract4‐Amino‐3‐cyanopyrazole (6) had once been considered to be a possible intermediate in the photochemical conversion at 350 nm of diaminomaleonitrile (1) into 4‐amino‐5‐cyanoimidazole (3), a precursor of adenine. The pyrazole was synthesized and irradiated at 350 nm. No isomerization into the imidazole was observed, even when the photolysis was carried out in the presence of an excess of 1, where sensitization by this or one of its photolysis products might have operated. At 254 nm, complete decomposition of 6 was observed, with formation of polymeric products. At 300 nm, 6 underwent isomerization to 3, as well as extensive decomposition. Hydrogen cyanide was probably produced, which reacted with the remaining starting material to yield 7‐aminopyrazolo[4,3‐d]pyrimidine (10), which did not isomerize into adenine under the photolysis conditions. A polymer was also obtained, from which glycine was identified after hydrolysis.
The synthesis and chelation properties of oximes of certain 2‐quinolylmethyl and 2‐phenanthrolylmethyl ketones and of various hydrazones of 2‐acetylquinoline and 2‐acetyl‐1,10‐phenanthroline
Authors: Case Francis H. , Schilt A. A. 
Published: April 2009

AbstractCertain oximes were prepared from 2‐quinolylmethyl 2‐pyridinyl ketone and 2‐(1,10‐phenanthrolyl)methyl 2‐pyridinyl ketone. Also, the preparation of two series of hydrazones was effected: one from 2‐acetylquinoline and one from 2‐acetyl‐1,10‐phenanthroline. The latter compound and 2‐(2‐quinolyl)‐1,10‐phenanthroline were also synthesized. All the compounds were tested for their metal‐chelation properties.
Nouveaux dérivés tricycliques du benzimidazole
Authors: Guerret Patrick , Langlois Michel 
Published: April 2009

AbstractUne réaction générale acido catalysée d'hétérocyclisation de céto‐2 (hydroxyéthyl)‐1 benzimidazole en présence d'un alcool ou d'un thiol est décrite. Les méthodes de preparation de nouveaux dérivés amino alcoylés tricycliques du benzimidazole sont données.
[1] Benzofuro[2,3‐d] pyridazines. VI. Etude des reactions de scission des acyltetrahydrobenzofuropyridazones
Authors: Robba Max , De Sevricourt Michel Cugnon , Godard Anne‐Marie 
Published: April 2009

AbstractLes réactions de scission du cycle pyridazinique des acyltétrahydrobenzofuropyridazones sont réalisables par hydrolyse, alcoolyse ou aminolyse et elles concernent la liaison lactamique‐3,4. Elles conduisent à des dérivés benzofuranniques portant sur le sommet 2 des groupements acide, ester, amide ou hydrazide et sur le sommet 3 des groupements méthylhydrazine éventuelle‐mentacylés. Les réactions de cyclisation effectuées sur l'acide hydrazinométhyl‐3 benzofuranne‐carboxylique‐2 ou sur ses dérivés ainsi que sur le bromométhyl‐3 benzofurannecarboxylate d'éthyle‐2 représentent une nouvelle synthèse des tétrahydrobenzofuropyridazones.
Triazino‐1,2,4‐[4,5‐a] indoles IV. Etude des triazinoindolethiones
Authors: Robba Max , Maume Daniel , Lancelot Jean‐Charles 
Published: April 2009

AbstractLes triazinoindolethiones 2 et 3 obtenues par thionation des triazinoindolones 1 et 4 constituent des intermédiaires permettant d'accéder aux triazinoindoles 10 et 19 et qui se prêtent, par suite de leur équilibre tautomère avec des formes thiolactimes, à des réactions de N‐substitution et de S‐substitution. La méthylation conduit à des mélanges de dérivés N‐ et S‐méthylés qui out été séparés par chromatographie et identifiés par rmn 1H et par synthèse univoque.
Synthetic and structural studies of some chloro‐substituted methyl 2,1‐benzisoxazole‐3‐carboxylates and related compounds
Authors: Mccord Tommy J. , Smith David R. , Swan Janet K. , Goebel Anna M. , Thornton Donald E. , Yakshe Criss C. , Davis Alvie L. 
Published: April 2009

AbstractMethyl 5‐chloro‐ and 5,7‐dichloro‐2,1‐benzisoxazole‐3‐carboxylates have been synthesized by treatment of o‐nitromandelic and 5‐chloro‐2‐nitroamandelic methyl esters, respectively, with thionyl chloride under appropriate reaction conditions. The structural assignments of both heterocyclic products were based on elemental and spectral analyses, and their conversion to the corresponding 5‐chloro‐ and 5,7‐dichloro substituted 2,1‐benzisoxazole‐3‐carboxylic acids and isatins. Methyl α‐chloro‐o‐nitrophenylacetate and o‐nitrophenylcarbomethoxymethinyl sulfite were also obtained from reactions of methyl o‐nitromandelate and thionyl chloride. A possible reaction mechanism involving two consecutive nucleophilic substitutions of methyl o‐nitromandelate with thionyl chloride was proposed to account for the formation of methyl 5‐chloro‐2,1‐benzisoxazole‐3‐carboxylate.
Mass spectrometry of nucleoside derivatives. Seleno analogs of purine and pyrimidine bases and nucleosides
Authors: Liehr J. G. , Weise C. L. , Wise Dean S. , Townsend Leroy B. , Crain P. F. , Milne George , Mccloskey James A. 
Published: April 2009

AbstractMass spectra of certain selenobases and selenonucleosides, and some of their trimethylsilyl and O,N‐permethyl derivatives have been studied from the standpoint of structural characterization, and in order to ascertain the influence of selenium on normal fragmentation patterns. Molecular ion abundances of the selenouracils are intermediate between those of the corresponding oxygen and sulfur analogs. Fragmentation processes are similar to those of the corresponding normal bases and nucleosides but with additional ions resulting from expulsion of Se or SeH in most cases. Trimethylsilylation occurs at approximately the same rate as for normal bases and nucleosides but the products show decreasing stability with prolonged heating. A least squares procedure is demonstrated which generates monoisotopic mass patterns and assists in interpretation of the mass spectra.
Condensation reactions of a comenaldehyde derivative
Authors: Looker James H. , Shaneyfelt Duane L. , Halfar Wayne 
Published: April 2009

AbstractCondensation reactions of comenaldehyde methyl ether (I) with malonic acid, ethyl cyanoacetate, and cyanoacetamide to give β‐(5‐methoxy‐4H‐pyran‐4‐on‐2‐yl)acrylic acid (II), ethyl 2‐cyano‐3‐(5‐methoxy‐4H‐pyran‐4‐on‐2‐yl)propenoate (III), and 2‐cyano‐3‐(5‐methoxy‐4H‐pyran‐4‐on‐2‐yl)propenamide (IV), respectively, are described. Ultraviolet absorption spectra for 2‐hydroxymethyl‐5‐methoxy‐4H‐pyran‐4‐one, I and II are presented.
1,3‐Dioxolium‐, 1,3‐dithiolium‐ und 1,3‐diselenolium‐ionen ‐ aromatische strukturen oder durch heteroatome stabilisierte carbeniumionen?
Authors: Timm Uwe , Plücken Udo , Petersen Hermann , Meier Herbert 
Published: April 2009

AbstractProtonation of the bases6, 7and8with trifluoroacetic acid was investigated on the basis of1–3C‐nmr measurements. Two models for the generated ions1–3are discussed. A decision is possible in favour of carbenium ions, which are stabilized by adjacent heteroatoms.
Stereospecific synthesis and antibiotic activity of some cephalosporin analogs
Authors: Bose Ajay K. , Ram Bhagat , Hoffman W. A. , Hutchison A. J. , Manhas M. S. 
Published: April 2009

AbstractThe strategy used for the stereospecific synthesis of benzofused octams as cepham analogs was the conversion of a 3,4‐dihydrothioisocarbostyril to a thioimidate, cycloaddition reaction to form a fused β‐lactam and subsequent removal of the alkylthio group by Raney nickel hydrogenolysis. Using azidoacetyl chloride for forming the β‐lactam and following known procedures, an amido side chain was generated. Two of the carba analogs of cephalosporin so produced showed low levels of antibacterial activity against a number of gram positive and gram negative organisms.
Introduction of a methoxyl group into indoles and 2,3‐dihydroindoles. A new synthesis of 5‐hydroxytryptamine (serotonin)
Authors: Saito Kunio , Kikugawa Yasuo 
Published: April 2009

AbstractMethoxylation of the 5‐position of indoles and indolines was investigated. Treatment of 5‐bromo‐iodoles and indolines with cuprous iodide and sodium methoxide in methanol/dimethylformamide afforded the corresponding methoxy compounds. This methoxylation reaction was applied to the new synthesis of serotonin.
Synthesis of tetronic acid enamine. Dienamine derivatives from 3‐(2H)furanones
Authors: Chantegrel Bernard , Gelin Suzanne 
Published: April 2009

AbstractThe synthesis of 5‐aryl (or alkyl) aminomethylene‐3‐(1‐amino or 1‐alkylaminoethylidene)‐2,4‐dioxo‐(3H,5H)furans and 5‐arylaminomethylene‐3‐(1‐hydroxyethylidene)‐2,4‐dioxo‐(3H,5H)furans (new 3‐acetyltetronic acid derivatives) are described. The stereochemistry of these compounds from the 1H nmr data is discussed.
3‐Substituted imidazo[1,5‐a]pyridines
Authors: Albrecht W. L. , Corona J. A. , Edwards M. L. 
Published: April 2009

AbstractCyclization of amides of 2‐aminomethylpyridine gave imidazo[1,5‐a]pyridines. In several examples the literature preparation (phosphorus oxychloride) gave extensive tar formation. The use of phosphorus trichloride‐triethylamine (−20°) gave the desired imidazo[1,5‐a]pyridines.
Studies on quinoline derivatives and related compounds. VI. A novel displacement reaction of 1‐ethylquinolinium iodides with nucleophiles
Authors: Agui Hideo , Nakagome Takenari 
Published: April 2009

AbstractThe reaction of 4‐amino‐ (3a) and 4‐anilino‐3‐carbethoxy‐1‐ethyl‐6,7‐methylenedioxy‐quinolinium iodide (3b) with nucleophilic reagents produced 7‐substituted 4‐amino‐3‐carboxy‐1‐ethyl‐6‐hydroxyquinolinium betaines (5b‐d) and 7‐substituted 1‐ethyl‐1,4‐dihydro‐6‐hydroxy‐4‐phenylimino‐3‐quinolinecarboxylic acid (6b‐d), respectively, which led to 7‐substituted 1‐ethyl‐1,4‐dihydro‐6‐hydroxy‐4‐oxo‐3‐quinolinecarboxylic acids (1b‐d) by alkaline hydrolysis. With a variety of 1‐ethyl‐1,4‐dihydroquinoline carboxylates (16a‐e) these novel displacement reactions were attempted.
Carbon‐13 NMR studies on 3‐phenyl‐as‐triazine 4‐oxides
Authors: Bennett G. B. , Kahle A. D. , Minor H. , Shapiro M. J. 
Published: April 2009

AbstractThe substituent chemical shifts of a series of para substituted‐3‐phenyl‐as‐triazine 4‐oxides were studied using the Swain‐Lupton F and R values. This data was compared to that obtained for parasubstituted biphenyls, phenyl pyrroles and phenyl furans. It was found that the substituent chemical shifts in the triazines behaved in a similar manner to that in the biphenyl system.
6‐ and 7‐aryl‐1,2,4‐triazolo[4,3‐b]‐1,2,4‐triazines. Synthesis and characterization
Authors: Trust Ronald I. , Albright J. Donald , Lovell F. M. , Perkinson N. A. 
Published: April 2009

AbstractSynthetic methods for the preparation of 6‐aryl‐1,2,4‐triazolo[4,3‐b]‐1,2,4‐triazines (1) and the 7‐aryl isomers (2) are described. Compounds 1 were prepared from aryl glyoxaldoximes 76 via 6‐aryl‐1,2,4‐triazin‐3(2H)ones (75). A simple procedure for the preparation of the 7‐aryl isomers was effected using arylglyoxals 11 and the triazoles (4, 12a and 12b). However, complete regioselectivity was not realized in all cases, especially when the triazoles were substituted at the C‐5 position. A regiospecific synthesis of the 7‐aryl isomers 2 was developed via the 3‐methylthio‐5‐aryl‐1,2,4‐triazines (61). The structure of the parent 6‐phenyl derivative 5 was confirmed by x‐ray crystallography.
Synthesis of 5,6‐dihydroxy‐2‐phenyl‐4‐pyrimidinecarboxylic acid, methyl ester, a corrected structure
Authors: Culbertson Townley P. 
Published: April 2009

AbstractPyrolysis of the adduct of benzamide oxime and dimethyl acetylenedicarboxylate leads to 5,6‐dihydroxy‐2‐phenyl‐4‐pyrimidinecarboxylic acid methyl ester (4a) rather than 4,5‐dihydro‐α,4‐dioxo‐2‐phenyl‐1H‐imidazole‐5‐acetic acid, methyl ester (1).
The synthesis of functionalized derivatives of pyrimido[4,5‐b][1,4]oxazines and side chain attachment
Authors: Winchester Merritt J. 
Published: April 2009

AbstractThe synthesis and reactions of 2‐amino‐4‐hydroxypyrimido[4,5‐b][1,4]oxazines with functionalities in the six position are described (1). The use of functionalities in the six position for coupling side chains to the pyrimido‐oxazine system is discussed and a successful coupling described.
Antiulcer agents. 2. Pyridyl oxime ethers
Authors: Moffett Robert Brace , Robert André , Schumann Edward L. , Paquette Lew A. 
Published: April 2009

AbstractA large number of pyridinecarboxaldehyde (and ketone) O‐substituted oximes were prepared by alkylating the oxime or by treating the parent aldehyde (or ketone) with an O‐substituted hydroxylamine. Many of these were converted to the N‐oxide. Screening revealed that many of these oxime ethers were active in preventing gastric ulcers in rats. Data on selected examples is given.
1,2,4‐Oxadiazoles. XI. An intermediate in the isomerization from nitrones to amides
Authors: Baiocchi L. , Picconi G. , Palazzo G. 
Published: April 2009

AbstractCertain 1,2,4‐oxadiazolyl‐aryl nitrones isomerize to the corresponding amides by heating in ethanol via stable intermediates, for which the structure of 1,2,4‐oxadiazolium inner salts was recognized.
Arylindoles. III. Mannich reaction of 1‐arylindoles
Authors: Khan Misbahul Ain , Rocha Emely Kazan 
Published: April 2009

Abstract1‐Phenyl‐, and 1‐nitrophenylindoles when subjected to Mannich reaction conditions gave the corresponding 3‐dialkylaminomethyl derivatives (IIc‐IIk) in good yields.
Etude théorique des cycloadditions à partir dM'ylures d'azinium ou de composés homologues
Authors: Arriau Jean , Maury Catherine , Maury Georges 
Published: April 2009

AbstractL'étude théorique des réactions citées dans le titre a été abordée en utilisant une méthode perturbationelle. Les résultats des calculs permettent de retrouver les orientations préférentielles expérimentales de la réaction lorsqu'elles correspondent à des différences d'énergie de stabilisation importantes.
Syntheses of 2‐hydroperoxy‐and 2‐hydroxy‐2H‐imidazoles
Authors: Graziano M. L. , Curato G. , Scarpati R. 
Published: April 2009

AbstractOxidation of fully substituted imidazoles 1 by singlet oxygen gives in good yield fully substituted 2‐hydroperoxy‐2H‐imidazoles 2. Reduction of 2 by triphenylphosphine leads to 2‐hydroxy‐2H‐irnidazoles 3. Limitations of the methods are reported.
Synthèse et réactivité de nitro indazoles
Authors: Benchidmi Mohamed , Bouchet Philippe , Lazaro RenÉ 
Published: April 2009

AbstractLa synthèse et les propriétés spectroscopiques en rmn de 44 dérivés nitrés de l'indazole dont 23 sont décrits pour la première fois, ont été étudiées. En fonction des rendements, on indique la meilleure voie d'accés aux dérivés halogénés méthyle's (halogénation avant ou après méthylation du nitro indazole). La réactivité' relative des différents sites du cycle vis à vis de l'agent électrophile est discutée.
Indole related compounds. Reaction of 1‐protected‐indoles with pyridine substrates
Authors: Caixach J. , Capell R. , Galvez C. , Gonzalez A. , Roca N. 
Published: April 2009

AbstractThe products resulting from the reactions of 1‐benzenesulfonyl‐2‐lithioindole and 2‐lithio‐1‐methylindole with different pyridine substrates (pyridine, 1‐methoxy‐pyridinium salt and 2‐bromopyridine) have been studied. The use of lithiocyclohexylisopyropylamide as a lithiating agent of indoles has been investigated. The preparation of four of the possible benzenesulfonyl derivatives of 2‐(2′ ‐pyridyl)indole is described.
Reduction of 1,2‐diaroyl‐1,2‐diazetidines by lithium aluminum hydride
Authors: Landis Michael E. , Mitchell John C. 
Published: April 2009

AbstractReaction of a series of four‐membered ring hydrazides (1,2‐diaroyl‐1,2‐diazetidines) with lithium aluminum hydride at 80° results in reductive saturation of both carbonyl groups affording 1,2‐diaryl‐1,2‐diazetidines in modest yield. Reactions at 22° result in reductive fragmentation at one carbonyl moiety, producing a monoaroyl‐1,2‐diazetidine as the exclusive product. A mechanism similar to that postulated for the temperature‐dependent reduction of amides by lithium aluminum hydride is proposed for the reduction of these 1,2‐diazetidines.
Zur photochemie des β‐pyridinalanilins
Authors: Behjati B. , Bluhm Th. 
Published: April 2009

Abstractβ‐Pyridinalanilin läβt sich im Gegensatz zu alien anderen als Schiffsche Base vorliegenden Diazastilbenen nicht zu Diazaphenanthrenen cyclisieren. Stattdessen ergibt sich durch Photohydration Chinolin‐3‐aldehyd.
Zur photolyse des benzotriazols
Authors: Razmara F. , Behjati B. , Aftandilians N. , Bluhm Th. 
Published: April 2009

AbstractThe photolysis of 1H‐benzotriazole in the presence of benzene produces two products, namely 2‐aminobiphenyl and 1‐anilinobenzotriazole isolated as 2‐acetylaminobiphenyl and 1‐(N‐ acetylanilino)benzotriazole, respectively, upon chromatography on Kieselgel 60.
Préparation d'isoxazoles trisubstitués par réduction chimique et électrochimique d'α‐acyl β‐nitrostilbènes
Authors: Bellec Christian , Bertin Daniel , Colau Roger , Deswarte StÉPhane , Maitte Pierre , Viel Claude 
Published: April 2009

AbstractLa nitration par le peroxyde d'azote d'α‐acylstilbènes conduit aux α‐acyl β‐nitro stilbènes correspondants. Ceux‐ci, par réduction chimique ou électrochimique en milieu acide, conduisent, avec de bons rendements, à des isoxazoles trisubstitués.
Synthesis of Pyranthiones
Authors: Van Allan J. A. , Reynolds G. A. , Stenberg J. F. 
Published: April 2009

AbstractA general method for the preparations of pyranthiones is particularly useful for preparing substituted xanthiones which are unavailable by established procedures. Reaction of a xanthone with p‐tosyl isocyanate or with trichloroacetyl isocyanate produces the corresponding imino derivatives, which upon treatment with n‐butylamine followed by hydrogen sulfide gives the desired xanthione in good yield.
A Convenient Synthesis of Certain Benzo and Dibenzoxanthones and Chromones
Authors: Van Allan J. A. , Stenberg J. F. , Reynolds G. A. 
Published: April 2009

AbstractCertain chromones and benzoxanthones were prepared by heating at 300–325° a mixture of 1‐or 2‐naphthol with either phenyl o‐hydroxybenzoate or o‐hydroxynaphthoate or a β‐ketoester. The yields and purity of the products are superior to those obtained by the published procedures.
Constituents of cannabis sativa L. XVI. A possible decomposition pathway of Δ9‐tetrahydrocannabinol to cannabinol
Authors: Turner Carlton E. , Elsohly Mohmoud A. 
Published: April 2009

AbstractA pathway is proposed for the decomposition of Δ9‐tetrahydroeannabinol (I) and its Δ8‐isomer (IX) with the eventual formation of cannabinol (II) through epoxy and hydroxylated intermediates.
Hétérocyclisation de la nor‐3 ar‐himachalone‐9
Authors: Fkih‐Tetouani Souâd , Daunis Jacques , Jacquier Robert , Viallefont Philippe 
Published: April 2009

AbstractNous avons pu facilement accoler au cycle à sept chainons de la nor‐3 ar‐himachalone‐9 différents hétérocycles à trois ou cinq chainons; la formation d'hétérocycles à six chainons est beaucoup plus difficile, celle d'hétérocycles à sept chainons n'a pas été possible.
Angular polycyclic thiophenes containing two thiophene rings. I
Authors: Kudo Hirotaka , Tedjamulia Marvin L. , Castle Raymond N. , Lee Milton L. 
Published: April 2009

AbstractWe describe the synthesis of thieno[2,3‐c]dibenzothiophene (6), thieno[3,2‐c]dibenzothiophene (10), thieno‐[3,2‐a]dibenzothiophene (14), thieno[2,3‐a]dibenzothiophene (16), benzo[1,2‐b:4,3‐b]bisbenzo[b]thiophene (18), benzo[1,2‐‐6:3,4‐b]bisbenzo[b]thiophene (20), benzo[2,1‐‐6:3,4‐b]bisbenzo[b]thiophene (22), benzo[1,2‐b:3,4‐g]bisbenzo[b]thiophene (27), benzo[1,2‐b:4,3‐e]bisbenzo[b]thiophene (29), benzo[2,1‐‐6:3,4‐g]bisbenzo[b]thiophene (36), benzo[2,1‐‐6:4,3‐e]bisbenzo[b]thiophene (38), benzo[1,2‐‐6:4,3‐g]bisbenzo[b]thiophene (41), benzo[1,2‐b:4,5‐g]bisbenzo[b]thiophene (42), benzo[1,2‐b:3,4‐e]bisbenzo[b]thiophene (44) and benzo‐[1,2‐b:5,4‐e]bisbenzo[b]thiophene (45).
Reactivity of thienopyrroles. Synthesis of isomeric nitro and bromothienopyrroles
Authors: Eras J. , Gálvez C. , Garct́a F. 
Published: April 2009

AbstractThe preparation of ethyl 2‐bromothieno[2,3‐b]pyrrole‐5‐carboxylate, ethyl 2‐bromothieno[3,2‐b]pyrrole‐5‐carboxylate, ethyl 2‐nitrothieno[2,3‐b]pyrrole‐5‐carboxylate and ethyl 2‐nitrothieno[3,2‐b]pyrrole‐5‐carboxylate are described.