bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does maintenance lithium therapy prevent recurrences of mania under ordinary clinical conditions?
Authors: Dickson W. E. , Kendell R. E. 
Published: July 2009

SynopsisMental-hospital admission rates in Edinburgh for mania, schizophrenia and psychotic depression were studied from 1970 to 1981, a 12-year period during which long-term lithium therapy was increasingly employed in affective illnesses. If this treatment had been effective admission and readmission rates for mania, and perhaps also for depression, should have fallen progressively. In fact, they rose steadily, while the admission rate for schizophrenia fell. These changes could not easily be attributed to changing diagnostic criteria, to the admission of milder affective illnesses, or to poor and deteriorating lithium surveillance. Their explanation is uncertain, but they cast some doubt on the efficacy of lithium prophylaxis in ordinary clinical practice.
Endocrine and behavioural responses to methylphenidate in depression
Authors: Joyce Peter R. , Donald Richard A. , Nicholls M. Gary , Livesey John H. , Abbott Robyn M. 
Published: July 2009

SynopsisTwenty patients with a major depressive disorder and 20 control subjects were subjected to a 1 mg dexamethasone suppression test (DST) and a challenge with intravenous (IV) methylphenidate (MP)(0·3 mg/kg). None of the controls, but 9 depressives, were DST non-suppressors. Among the depressives there were correlations between DST-cortisol and baseline (4 p.m.) levels of cortisol, growth hormone, prolactin and adrenaline. Compared with the controls the depressives had a decreased cortisol response and an enhanced adrenaline response to the MP challenge. The decreased cortisol response was not related to either DST-cortisol or baseline cortisol, but was correlated with the mood response to MP.
Psychological and physical morbidity in the aftermath of a cyclone
Authors: Fairley M. , Langeluddecke Pauline , Tennant Christopher 
Published: July 2009

SynopsisA Fijian community affected by a cyclone was compared with an unaffected but similar community. Two months after the cyclone both psychological and physical morbidity was 2–3 times greater in the affected community than in controls. By the third month morbidity had resolved to levels similar to those in the unaffected population. Brief, catastrophic stress without loss of life appears to provoke psychological and physical morbidity of relatively brief duration.
Mental health care in Southern Italy: application of case–control methodology for the evaluation of the impact of the 1978 psychiatric reform
Authors: Bollini Paola , Muscettola Giovanni , Piazza Antonella , Puca Maurizio , Tognoni Gianni 
Published: July 2009

SynopsisA survey to analyse patients' characteristics and the care delivered to them was conducted in several psychiatric facilities, covering the whole range of care offered in the public sector in two regions of Southern Italy. A case–control method of analysis was chosen, and the relative risk estimates (RR), together with their 95% confidence intervals (CI), of being in custodial facilities were computed, comparing patients treated in custodial institutions (‘cases’) with those in community-based services (‘controls’) in respect of social and clinical vairables. Factors more stongly associated with custodial treatment were: illiteracy (RR = 2·4), unmarried status (RR =2·4), a history of prolonged illness (RR = 7·6), organic diagnosis (RR = 2·6), previous custodial treatment (RR = 3·9), and expected poor social functioning (RR =2·4). The suitability and advantages of the case–control method of analysis in the field of psychiatric care evaluation are discussed.
Platelet monoamine oxidase activity and life stress as predictors of psychopathology and coping in a community sample
Authors: Irving Joanne Boyd , Coursey Robert D. , Buchsbaum Monte S. , Murphy Dennis L. 
Published: July 2009

SynopsisThe present study, using a diathesis-stress model, attempted to confirm prior findings with platelet monoamine oxidase (MAO) activity and stress in a middle-aged, non-clinic population. One hundred and seventy-eight adult males from a statewide community club were tested for platelet MAO activity and stressful life events and were also given a variety of psychological measures of both psychopathology and psychosocial coping. The data were examined both for correlations across the total sample and for a comparison of high-risk groups (top and bottom 15% of MAO activity) with a middle MAO group. Low platelet MAO activity was related to a higher incidence of contact with mental health professionals, and more frequent use of alcohol and cigarette smoking. High MAO activity was related to higher levels of anxiety and somatization. High levels of stress were related to increased psychosocial problems reported for female and family members, higher scores on two schizophrenia-related MMPI scales (schizophrenia and paranoia subscales), but fewer idiosyncratic associations, elevated hypomanic, depression, and anxiety scores, increased alcohol use, and increased use of prescribed antianxiety and sedative medication. Neither MAO nor stress were related to current levels of psychosocial coping. Moreover, no interaction effects were uncovered for MAO activity and stress combined.
The struggle to be thin: a survey of anorexic and bulimic symptoms in a non-referred adolescent population
Authors: Whitaker Agnes , Davies Mark , Shaffer David , Johnson Jim , Abrams Sari , Walsh B. Timothy , Kalikow Kevin 
Published: July 2009

SynopsisNinety-one per cent of a county-wide high school population (N= 5596) completed the Eating Symptoms Inventory (ESI) and the Eating Attitudes Test (EAT). Being female, older and heavier are far more strongly associated with anorexic and bulimic symptoms than is social class. ESI approximations of the DSM-III criteria for anorexia nervosa or bulimia suggest that while both conditions are rare (less than 1%), bulimia is the more prevalent disorder.
Recent friendships in anxious and depressed school age children
Authors: Goodyer I. M. , Wright C. , Altham P. M. E. 
Published: July 2009

SynopsisA consecutive series of school age children (7 to 16 years) with emotional disorders (N = 100) were compared with a series of community controls (N = 100) matched for age, sex and social class for the quality of their friendships. A semi-structured interview was developed to measure the quality of friendship for this purpose. Significantly more (48%) children with emotional disorder were likely to be rated as experiencing moderate to poor friendships in the 12 months prior to the onset of symptoms than were controls (16%) in the 12 months prior to interview. Prepubertal children with moderate to poor friendship patterns were classified as either predominantly anxious or depressed. Postpubertal children with moderate to poor friendships patterns were, in contrast, predominantly anxious. These findings suggest that puberty denotes a point of change for the impact of friendship deficits on the psychopathology of emotional disorder. There were no sex differences in the clinical classification of children with moderate or poor friendship patterns.
Locus of control in women with eating pathology
Authors: King Michael 
Published: July 2009

SynopsisLocus of control scales have been used to measure ‘effectiveness’ or personal control in patients with eating disorders. A locus of control of behaviour scale was used in a community sample of women with a spectrum of eating pathology from bulimia nervosa to chronic dieting as well as in a comparison group of non-dieters. This scale appeared to add nothing over and above general measures of psychopathology as assessed by the Clinical Interview Schedule and the Symptom Rating Test, or more specific measures such as the Eating Attitudes Test.
Bulimia nervosa in the male: a report of nine cases
Authors: Robinson P. H. , Holden N. L. 
Published: July 2009

SynopsisNine male patients with bulimia nervosa, accounting for one in 24 bulimic patients attending a clinic for eating disorders, are described. Symptomatology and demographic characteristics were similar in males and females. A history of either anorexia nervosa or obesity was always present, and a chronic course was seen in 6 patients. Five of the men showed atypical sexuality.
Early manifestations and first-contact incidence of schizophrenia in different cultures: A preliminary report on the initial evaluation phase of the WHO Collaborative Study on Determinants of Outcome of Severe Mental Disorders
Authors: Sartorius N. , Jablensky A. , Korten A. , Ernberg G. , Anker M. , Cooper J. E. , Day R. 
Published: July 2009

SynopsisIn a context of a WHO collaborative study, 12 research centres in 10 countries monitored geographically defined populations over 2 years to identify individuals making a first-in-lifetime contact with any type of ‘helping agency’ because of symptoms of psychotic illness. A total of 1379 persons who met specified inclusion criteria for schizophrenia and other related non-affective disorders were examined extensively, using standardized instruments, on entry into the study and on two consecutive follow-ups at annual intervals. Patients in different cultures, meeting the ICD and CATEGO criteria for schizophrenia, were remarkably similar in their symptom profiles and 49% of them presented the central schizophrenic conditions as defined by CATEGO class S+. However, the 2-year pattern of course was considerably more favourable in patients in developing countries compared with patients in developed countries, and the difference could not be fully explained by the higher frequency of acute onsets among the former. Age- and sex-specific incidence rates and estimates of disease expectancy were determined for a ‘broad’ diagnostic group of schizophrenic illness and for CATEGO S+ cases. While the former showed significant differences among the centres, the differences in the rates for S+ cases were non-significant or marginal. The results provide strong support for the notion that schizophrenic illnesses occur with comparable frequency in different populations and support earlier findings that the prognosis is better in less industrialized societies.
Experiences of alien control in schizophrenia reflect a disorder in the central monitoring of action
Authors: Frith Christopher D. , Done D. John 
Published: July 2009

SynopsisTwenty-three acute psychotic patients who were drug free at the time of testing performed a motor task designed to elicit many errors. Normal subjects and many of the psychotic patients were able to correct these errors in the absence of visual feedback. The ability to make such corrections depends on the subject knowing what response he has just made. Patients with experiences of alien control of their thoughts and actions who formed a subgroup of those classified as schizophrenic, were significantly less likely to make error corrections in the absence of visual feedback. This result is consistent with our previous suggestion (Frith, 1987) that these symptoms are a consequence of problems with the central monitoring of responses.
A comparison of practices, attitudes and interactions in two established units for people with a psychiatric disability
Authors: Allen C. I. , Gillespie C. R. , Hall J. N. 
Published: July 2009

SynopsisThis study evaluates and compares aspects of residential care in a community hostel setting and a hospital setting for people with a psychiatric disability. The clients were assessed to establish their level of general functioning, the comparison indicating there was no significant difference between the two groups on the measure used. A previously published protocol was used as a method of comparing the units. The findings indicated that the hospital unit was more individually orientated both in practices and staff attitudes, and had staff who were more optimistic about clients' potential accomplishments. No differences were found between perceived involvement of staff in decision making, or staff–resident interactions.These findings have implications for the ‘Care in the Community’ movement, as they indicate that the nature of a service is as important as its location. They suggest that the relocation of services to the community in itself will not automatically overcome some of the difficulties associated with institutional care.
An analysis of the re-test artefact in longitudinal studies of psychiatric symptoms and personality
Authors: Jorm A. F. , Duncan-Jones P. , Scott R. 
Published: July 2009

SynopsisWhen general population samples are assessed on two occasions with psychiatric symptom or personality measures, a mean change in scores towards less psychopathology is often observed. This re-test artefact is a potential threat to the validity of longitudinal studies. Data from a longitudinal general population study were analysed to discover under what circumstances the re-test artefact occurs. It was found that the artefact is unrelated to the time lag between occasions, being equally strong at intervals ranging from 4 to 34 weeks. However, the artefact did not occur for all measures, but was confined to those assessing negative self-characteristics and administered orally by an interviewer. These findings are consistent with both the ‘mechanical responding’ and ‘social desirability’ hypotheses of the re-test artefact.
Psychiatric morbidity in an Italian general practice
Authors: Bellantuono Cesario , Fiorio Roberto , Williams Paul , Cortina Patrizia 
Published: July 2009

SynopsisA two-stage screening strategy was applied in a single-handed general practice in northern Italy. The study was designed so that all the second-stage psychiatric interviews were conducted during the first phase of the study (group A patients), while self-report questionnaire (GHQ) and GP assessments only were collected during the second phase (group B patients).The estimated true case rate of psychiatric disorder (36%) did not differ between the two phases of the study, but there were marked differences in the general practitioner's diagnostic behaviour. During the first phase (when psychiatric interviews were being conducted in the practice), her behaviour was heavily biased towards diagnosing psychiatric disorder; 61% of the patients were regarded by her as psychiatric cases and the hidden psychiatric morbidity rate was only 9%. During the second phase of the study (no psychiatric interviews in the practice), only 37% of the patients were regarded as psychiatric cases by the GP, and the hidden morbidity rate was 59%.The results are interpreted as demonstrating that the presence of a psychiatrist conducting a two-stage screening survey in the practice had a profound effect on the diagnostic threshold. They also provide support for the use of the GHQ as a case-finding instrument in general practice.
Obstetric complications in schizophrenia and the validity of maternal recall
Authors: O'Callaghan Eadbhard , Larkin Conall , Waddington John L. 
Published: July 2009

SYNOPSISThe significance of the excess of obstetric complications which appears to characterize the histories of schizophrenic patients is critically dependent on the validity of the source of obstetric information, especially when this is obtained by maternal recall. Twenty-one biological mothers of 17 schizophrenic and four other patients were interviewed for their recollections of individual events characterizing the pregnancy and delivery relating to each patient. These were then compared with those events documented in maternity hospital records. Only in two of the 21 instances (9·5%) were inconsistencies of detail apparent which would have affected the designation of the relevant patient as having, or as not having, experienced major obstetric complication(s). It is concluded that maternal recall can be a surprisingly accurate source of obstetric information in relation to research on schizophrenia.
Gender, coping and psychosomatic symptoms
Authors: Vingerhoets Ad J. J. M. , Van Heck Guus L. 
Published: July 2009

SYNOPSISIn this study gender differences in coping were explored, using the Ways of Coping Checklist (WCC; Folkman & Lazarus, 1980). In addition, the focus was on sex differences in the predictive value of coping strategies in relation to psychosomatic symptoms. Males preferred problem-focused coping strategies, planned and rational actions, positive thinking, personal growth and humour, day-dreaming and fantasies. Women preferred emotion-focused coping solutions, self-blame, expression of emotions/seeking of social support, and wishful thinking/emotionality. In spite of the gender differences the results of multiple regression analyses indicated congruous relationships between coping and complaints for both sexes. Stressors and coping factors contributed in much the same way to the explained variance of symptoms and the results were generally similar for males and females. The present data also emphasize the bidirectionality of the coping–symptoms link. This holds especially for self-blame, day-dreaming and fantasizing, and wishful thinking/emotionality. In contrast, distancing was found to be associated with self-reported psychosocial load. Future prospective studies should explicitly pay attention to this bidirectional relationship.
The identification of psychiatric disorders in children who fail to attend school: a cluster analysis of a non-clinical population
Authors: Bools Christopher , Foster Janet , Brown Imogen , Berg Ian 
Published: July 2009

SYNOPSISInterviews were conducted with parents of 100 children taken to a ‘School attendance committee’, because of persistent failture to attend School. Clinical assessmen t of the attendance problem was carried out so that children were categorized as ‘School refusers’ (N = 24), ‘truants’ (N =53), ‘both refusers and truants’ (N =9), or as ‘neither’ (N =14). Any ICD-9 psychiatirc disorder was separately identified. Cluster analysis of information collected in a standard way indicated that there was a group of children with the features of ‘School refusal’ who often had genralized neurotic disorders as well and who were mostly girls, another group with the feature of ‘truancy’ all of whom had conduct disorders who were mainly boys, and a third cluster of childrsen who were usually ‘truants’ but less often psychiatrically disturbed. The study provided evidence for the existence of School refusal with and without generalized neurotic disturbance in a non-clinical population.
Psychoactive drug effect on behavioural changes induced by prolonged socio-environmental deprivation in rats
Authors: Valzelli L. , Bernasconi S. 
Published: July 2009

SynopsisSeveral so-called ‘non-specific’ or ‘non-drug’ factors are known to interfere with the response to psychotropic drug administration. Animal emotionality has been reported to change the outcome of psychoactive drug administration, so that the response to a stimulant or depressant drug may considerably change according to the baseline state of activity of the central nervous system. Prolonged socio-environmental deprivation or isolation has been shown to produce in rats three different types of abnormal behaviour which have been tentatively defined as ‘friendly’, ‘indifferent’ and ‘muricide’. Such unusual changes in rat behaviour are assumed to reflect a series of different emotional changes. The present experiments show that psychoactive drugs can exert a different effect in relation to the different kinds of animal behaviour used in the experiments. The investigation of the properties of psychoactive compounds, as performed in experimental animals showing behavioural alterations, is then suggested as being more fruitful in providing much information closer to the clinical results than that achieved with the experiments performed in normal laboratory animals.
Religious stigmatization: an historical and psychophysiological enquiry
Authors: Whitlock F. A. , Hynes J. V. 
Published: July 2009

SYNOPSISThe historical accounts of religious stigmatization occurring during the past 750 years have been surveyed, with more detailed attention being given to late nineteenth- and twentieth-century medical investigations of some well-known cases. A case showing some features of religious stigmatization is described. The possible relationship of the phenomena of religious stigmatization to disease and psychophysiological processes in the subject is examined.
Contribution of life events to causation of psychiatric illness
Authors: Paykel E. S. 
Published: July 2009

SYNOPSISThis paper discusses the magnitude of the effect of life events in the causation of psychiatric illness. It is argued that an established epidemiological concept, relative risk, provides a useful measure of association which can be approximately adapted for retrospective controlled studies. Examination of studies employing general population controls consistently indicates effects of some importance, with risks of illness increased by factors of between 2 and 7 in the 6 months after an event. Risks are greater for the more stressful types of events, greater for depression and neuroses than schizophrenia, and even greater for suicide attempts. However, similar events occur commonly and a large proportion of event occurrences are not followed by illness. Events must interact with a wide variety of background factors, and the appropriate model is one of multifactorial causation.
A reappraisal of alcoholic psychoses
Authors: Cutting John 
Published: July 2009

SYNOPSISA retrospective study of alcoholic psychoses is reported. The phenomena of the illnesses corresponded poorly with classical descriptions of alcoholic hallucinosis, delirium tremens and alcoholic paranoia. Alternative diagnostic approaches were tried (Catego, restrictive definition of alcoholic hallucinosis). The problems of distinguishing psychoses with associated organic factors from ‘idiopathic’ forms are discussed.
Experimental and clinical evidence of the antidepressant effect of a beta-adrenergic stimulant
Authors: Simon P. , Lecrubier Y. , Jouvent R. , Puech A. J. , Allilaire J. F. , Widlöcher D. 
Published: July 2009

SYNOPSISA group of 49 patients with depressive illness were treated in an uncontrolled study by the intravenous administration of the beta-adrenergic stimulant, salbutamol. The results suggested a rapid antidepressant action in the majority of cases without significant adverse effects.
Historical terminology of eating disorders
Authors: Parry-Jones Brenda 
Published: July 2009

SYNOPSISUsing a wide range of rare, early printed sources, including literary material, some of the first English language dictionaries, medical lexicons and medical texts, the historical origins, development and application of five terms relating to eating abnormalities are investigated. It is demonstrated that four of these, which are in current psychiatric usage, exhibited notable consistency of meaning and application over many centuries.
Dementia in idiopathic Parkinson's disease: prevalence and relationship with symptoms and signs of Parkinsonism
Authors: Ebmeier K. P. , Calder S. A. , Crawford J. R. , Stewart L. , Cochrane R. H. B. , Besson J. A. O. 
Published: July 2009

SYNOPSISA whole population cohort of 157 patients with idiopathic Parkinsonism, most of whom had previously been clinically examined by Mutch (1986 a), were assessed to determine prevalence figures for dementia and examine the relationship between dementia, cognitive impairment and Parkinsonian signs. Dementia according to DSM-III-R criteria was diagnosed in 23·3% of all patients (95% confidence interval: 17·1 to 32·4%). Dementia and cognitive impairment were associated with overall measures of Parkinsonian impairment and rigidity, but not tremor, even after controlling for age, sex and education.