bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Wellbeing Through Reading”: The Impact of a Public Library and Healthcare Library Partnership Initiative in England
Authors: Phul Anita , Gorring Hélène , Stokes David 
Published: June 2024

Objective – This project sought to build upon a reader development tool, Many Roads to Wellbeing, developed by a health librarian in a mental health NHS Trust in Birmingham, England, by piloting reading group sessions in the main public library in the city using wellbeing-themed stories and poems. The aim was to establish whether a “wellbeing through reading” program can help reading group participants to experience key facets of wellbeing as defined by the Five Ways to Wellbeing.
Methods – The program developers ran 15 monthly sessions at the Library of Birmingham. These were advertised using the Meetup social media tool to reach a wider client base than existing library users; members of the public who had self-prescribed to the group and were actively seeking wellbeing. A health librarian selected wellbeing-themed short stories and poems and facilitated read aloud sessions. The Library of Birmingham provided facilities and a member of staff to help support each session.
Results – A total of 131 participants attended the 15 sessions that were hosted. There was a 95% response rate to the questionnaire survey. Of the respondents, 91% felt that sessions had helped them to engage with all of the Five Ways to Wellbeing. The three elements of Five Ways to Wellbeing that participants particularly engaged with were Connect (n=125), Take Notice (n=123), and Keep Learning (n=124).
Conclusion – The reading program proved to be successful in helping participants to experience multiple dimensions of wellbeing. This project presents a new way of evaluating a bibliotherapy scheme for impact on wellbeing, as well as being an example of effective partnership working between the healthcare sector and a public library.
Erratum to: Comparing the effectiveness of clomipramine and fluoxetine in dogs with anxiety-related behaviours
Authors: Williamson Olivia , Valera Valery , Minami Christopher , Tom Juliana , Powell Elizabeth , Norris Jeffrey W. 
Published: June 2024

Abstract
The original article was published in Veterinary Evidence Vol 9, Issue 1 (2024): https://doi.org/10.18849/ve.v9i1.679
In the original version of the article the contributions of one of the authors, Christopher Minami, were listed as "Investigation, Writing – Original draft". This has now been corrected to accurately reflect Minami's contributions, with the agreement of all the authors:
Christopher Minami: Conceptualisation, Methodology, Investigation, Writing – Original draft.
This error was in both the HTML and PDF versions. This has now been updated in both the HTML and PDF versions, and can be found in the author contributions section.
THE EFFECT OF TERA EXERCISE ON REDUCING ANXIETY LEVELS IN THE ELDERLY IN WONOHARJO VILLAGE, BUMI AGUNG DISTRICT, WAY KANAN LAMPUNG
Authors: Pamungkas Putri , Sumardiko Dwi Setiani , Hidayatullah Ariska Putri , Nur Cah Yanto Heri 
Published: June 2024

Introduction: Anxiety is a feeling of fear that is not clear and is not supported by the situation. Usually, anxiety or anxiety disorders will be accompanied by behavioral, emotional, and physiological changes (Kaliman, 2011) Anxiety in the elderly if not handled properly then the anxiety will have an impact on increasing mental disorders. Therefore, Tera exercise therapy is needed which is expected to reduce anxiety in the elderly Methods: The method in this study is a quantitative research type with a quasi-experimental research design with a pretest post-test control group approach. The sample in this study was the elderly who suffered from anxiety as many as 36 respondents who met the inclusion criteria. Collecting data in the study using a questionnaire sheet and data analysis using the Wilcoxon rank test statistical test. Results: The results of the Wilcoxon sign rank test with SPSS for Windows with a significance level of = 0.05 obtained a P value = 0.001 (0.001 <0.05) then Ho is rejected which means there is an effect of Tera exercise on decreasing anxiety levels in the elderly in Wonoharjo Village, Bumi Agung District, Way Kanan Lampung. Conclusions: For elderly who experience anxiety ranging from severe, moderate, and mild levels using tera exercise therapy can reduce anxiety levels in the elderly because it can cause them elderly to relax, feel comfortable, and happy, and interact with other elderly people.
Information System Taplink in the Library Space
Authors: Maslova Yu. V. , Lukin D. A. , Lukina A. A. 
Published: June 2024

With the development of digitalization, new services are emerging that allow attracting users to libraries, personalizing services and automating processes of their comfortable provision, etc. In the context of transformation, libraries have to adapt to new realities, but at the same time, new opportunities appear every day to improve their work in the digital space. Many libraries today lack any clear strategy for working in the virtual space and do not investigate feedback from consumers.In the era of digitalization, it is necessary to implement software and service tools that allow positioning library as a modern comfortable space to meet the society’ information needs. Placing on the library website an interactive Taplink system, designed taking into account real capabilities of libraries, specialists, and user needs and aimed at comfortable access to library resources and consumer activation, may be one of such breakthrough tools. The object of the article is to present the results of the study of the new digital phenomenon – Taplink, as well as of the elaboration and implementation of the pilot project in the Republican Youth Library of Tatarstan in order to assess the effectiveness of the introduction of this digital platform into the library's activities, analyze the library interaction with consumers on this platform, study the statistics of visits and functioning of the interactive system.The proposed project is unique, because it has no analogues in most libraries of the Russian Federation, and the Taplink theme itself is presented only in publications of the business community and is not covered in scientific publications of the library industry. The results of the study can provide significant assistance in the development of a comfortable digital library space.
Book Scholar, Historian, Educator: to the Anniversary of Dmitry Arkadievich Elyashevich
Authors: Mutev V. A. 
Published: June 2024

The purpose of the article is to present a brief biobibliographical and historiographical outline of research activities of the book scientist, historian, teacher and bibliophile D. A. Elyashevich in the context of the evolution of domestic theory of book science. The main stages of the researcher's scientific and professional development are characterized, key areas of his elaborations are highlighted: Jewish press and works on Judaic studies, problems of censorship and censorship institutions in the Russian Empire, theory and methodology of book science. The medialogical approach to book theory and educational practice is substantiated as one of the fundamental achievements of D. A. Elyashevich.
The Altai Mining District Officers’ Activities for Acquisition of the Barnaul Public Library in 1830–1850
Authors: Shelestiuk K. N. 
Published: June 2024

The article examines the mining officials’ business correspondence in the Kolyvan-Voskresensk (Altai) mining district as a source of studying the book culture of the mid-XIX century. The details of acquisition and use of collections of the Barnaul Public Library in 1830-1850 are revealed basing on documents stored in the State Archive of the Altai Region. The purpose of the article is to elicit and analyze the information potential of the official documentation of functionaries of the Altai Mining District for studying the history of the book culture of Siberia. Special attention is paid to the accompanying documentation for the books received by the Kolyvan-Voskresensk plants. These documents allow us to identify the main thematic lines in the purchased literature, to characterize the sources of replenishment and options for using the collections of the Barnaul Public Library.The work of the library was primarily subordinated to the needs and goals of the mining industry of the Altai. In 1830–1850 it continued to participate in teaching and training of mining specialists, which influenced the specifics of collections building. Books could be purchased not only on the initiative of the Staff of the Corps of Mining Engineers, but also at the requests of employees of the Altai Mining District. In addition to specialized literature, the mining plants received works published by specialists who worked here for many years.The results of archival documents analysis clearly demonstrate that the incoming books were shared due to mining chief judgment between the Barnaul Public Library, the educational department, mining offices and other institutions in the structure of the Altai Mining District. Some archival documents reflect the titles, number and, in some cases, the cost of received books.The research shows that the office documents of the Altai Mining District can be used for the reconstruction of the composition of the book collection of the Kolyvan-Voskresensk plants and attribution of separate books from this collection.
The Average “Portrait” of SPSTL SB RAS Contemporary Reader
Authors: Vikhreva G. M. , Shevchenko M. A. 
Published: June 2024

The purpose of the article is to actualize the idea readers’ satisfaction with organization of work and quality of library and information services provided by the largest beyond the Urals information institution – State Public Scientific-Technological Library of the Siberian Branch of the Russian Academy of Sciences (SPSTL SB RAS). Data collection was conducted in 2023 by face-to-face questionnaire. The survey questions allowed the respondents to rate the library work in points and to express their opinions in a more detailed way. The responses gained were analyzed on quantitative and qualitative levels. The numerical results of the survey gave an overall picture of the readers' preferences and the level of their satisfaction with the library services. Qualitative analyses of the respondents' extended responses contributed to a deeper understanding of the essence of views expressed in them. Basing on the obtained data it was found that the readers of SPSTL SB RAS in general highly appreciated its collections and professional qualities of its staff, considered the conditions of staying in it comfortable. Nevertheless, the complaints expressed by the respondents about the electronic catalogues, the library website, the system of informing about the available services and facilities require prompt response of the relevant library departments. The results of the research allowed us to get the "portrait" of the contemporary SPSTL SB RAS reader, to identify strong and weak aspects in working with him and to formulate proposals that contribute to solving a number of identified problems and determine further steps to improve the library service system.
A Study to Identify Individuals At Risk To Be Affected By Pompe Disease Who Had PrevioUsly Been Given a Non-Specific OR Tentative DiagnosiS For Their MUsclEWeakness (Pompe PURSUE)
Authors: Laney Dawn , Banks Kayla A. , Botha Eleanor G. , Keever Maria , Long Valynne , Foley Allison L. 
Published: June 2024

Abstract

Background
Late-onset Pompe disease (LOPD) is an autosomal recessive lysosomal storage disorder that results in severe progressive proximal muscle weakness. Over time, reductions in muscle strength result in respiratory failure and a loss of ambulation. Delayed diagnosis of LOPD deprives patients of treatments that can enhance quality of life and potentially slow disease progression. The objective of this study is to determine if patients with a nonspecific diagnosis, such as muscle weakness, may have LOPD using retrospective chart review of patients seen at two centers: an academic center and a community health system.
Results
Initial data pulls identified 80,070 patients with one of the ICD-10 codes of interest. Chart review found 551 of these patients also had at least one lab value commonly abnormal in individuals with LOPD and of these 110 scored as “at-risk”. After removing phenocopies/other confirmed unrelated diagnoses, 46 individuals were contacted either directly or through their healthcare provider for genetic counseling. Three patients had pretest genetic counseling and were tested for decreased levels of acid-α-glucosidase. One patient was found to have deficient acid-α-glucosidase. Additionally, a physician educated through the program ordered LOPD testing for their patient and diagnosed them with LOPD.
Conclusion
This study confirms that a symptom-based scoring system and chart review combined with provider education can identify patients who are at increased likelihood to have a missed LOPD diagnosis.
Determination of biotin interference in pediatric obesity related ELISA research kits
Authors: Kahraman Ezgi Kürkçü , DONMA Orkide , Donma Mustafa Metin , YILMAZ Ahsen , GÜZEL SAVAŞ 
Published: June 2024

Abstract

Background
Although high-dose biotin interference is now considered in automated immunoassays, it has not yet been detected in manually studied research kits, especially with enzyme-linked immunosorbent assay (ELISA), and the possibility of biotin interference in these kits has not been demonstrated. The aims of our study were to determine the effects of biotin interference on various parameters, including leptin, leptin receptor (LEPR), ghrelin, acylated ghrelin, deacylated ghrelin, ghrelin receptor (GHSR), kisspeptin (KISS1), kisspeptin receptor (KISS1R), preptin, peroxisome proliferator activated receptor gamma (PPAR γ), nod-like receptor pyrin domain-containing 3 (NLRP3) and interleukin-18 (IL-18), which contribute to energy homeostasis in healthy and obese children.
Methods
Serum pools were prepared from healthy and obese individuals, and biotin concentrations in samples containing different amounts of biotin were measured via sandwich and competitive ELISA methods. In addition, possible biotin interactions were investigated by determining the concentrations of all the study parameters in serum pools containing different amounts of biotin.
Results
More consistent results were obtained with biotin-competitive, ghrelin-competitive, KISS1-competitive, GHSR, leptin and LEPR ELISA kits. Unexpectedly, high levels were detected in the biotin sandwich ELISA kit, indicating that biotin interference may also occur in manually run research kits.
Conclusions
Biotin exhibited an interference effect even in well-functioning, qualified kits, and this negative effect was less common in competitive kits. Biotin interference was closely associated with the quality of the research kit, the parameters studied and the presence of high biotin concentrations in the blood.
GMP-compliant automated radiosynthesis of [18F] SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)
Authors: Chen Lijuan , Li Xiaochen , Ge Yao , Li Huiqiang , Li Ruili , Song Xiaosheng , Liang Jianfei , Zhang Weifeng , Li Xiaona , Wang Xiaoqi , Wang Yunjuan , Wu Yaping , Bai Yan , Wang Meiyun 
Published: June 2024

Abstract

Background
A novel positron emission tomography (PET) imaging tracer, [18F] SynVesT-1, targeting synaptic vesicle glycoprotein 2 (SV2A), has been developed to meet clinical demand. Utilizing the Trasis AllinOne-36 (AIO) module, we’ve automated synthesis to Good Manufacturing Practice (GMP) standards, ensuring sterile, pyrogen-free production. The fully GMP-compliant robust synthesis of [18F] SynVesT-1 boosting reliability and introducing a significant degree of simplicity and its comprehensive validation for routine human use.
Results
[18F] SynVesT-1 was synthesized by small modifications to the original [18F] SynVesT-1 synthesis protocol to better fit AIO module using an in-house designed cassette and sequence. With a relatively small precursor load of 5 mg, [18F] SynVesT-1 was obtained with consistently high radiochemical yields (RCY) of 20.6 ± 1.2% (the decay-corrected RCY, n = 3) at end of synthesis. Each of the final formulated batches demonstrated radiochemical purity (RCP) and enantiomeric purity surpassing 99%. The entire synthesis process was completed within a timeframe of 80 minutes (75 ± 3.1 min, n = 3), saves 11 minutes compared to reported GMP automated synthesis procedures. The in-human PET imaging of total body PET/CT and time-of-flight (TOF) PET/MR showed that [18F] SynVesT-1 is an excellent tracer for SV2A. It is advantageous for decentralized promotion and application in multi-center studies.
Conclusion
The use of AIO synthesizer maintains high production yields and increases reliability, reduces production time and allows rapid training of production staff. Besides, the as-prepared [18F] SynVesT-1 displays excellent in vivo binding properties in humans and holds great potential for the imaging and quantification of synaptic density in vivo.
Finite Element Design Optimization by Doe Technique of the Torsional Stress Behavior for Niti Rotary Endodontic Instruments
Authors: Russo Franco Maria Di , Gisario Annamaria , Zanza Alessio , Natali Stefano , Ruta Giuseppe , Testarelli Luca 
Published: June 2024

Abstract

Nickel-Titanium (NiTi ) rotary endodontic instruments are fundamental in modern dentistry, as the greater mechanical properties and flexibility make the treatment of the root canal faster and more effective. The present study deals with an analysis of the mechanical behaviour of the NiTi endodontic instruments during the application of torsional stresses, through a finite element simulation model. The model simulates the interaction of rotary endodontic instruments within a curved conical canal, focusing on the impact of various geometric parameters. Key factors such as the cross-section, the pitch and the taper have been analysed to discern their influence on the mechanical performance of the instrument. Subsequently, a topological optimization was made to customize the design in order to improve the performance’s instrument under torsional stress. The investigation revealed a significant correlation between the polar moment of inertia of the resistant section and the stifness of the instrument. Through the variation of taper and pitch, individually or in combination, it was possible to identify ranges of parameter values for the definition of more flexible or more rigid behaviour. In particular, it was observed that lower taper increases the flexibility of the instrument, while a higher pitch increases flexibility.
Disrupted Host-Microbiota Crosstalk Promotes Nonalcoholic Fatty Liver Disease Progression by Impaired Mitophagy
Authors: Yin Wenjing , Gao Wenxing , Yang Yuwei , Lin Weili , Chen Wanning , Zhu Xinyue , Zhu Ruixin , Zhu Lixin , Jiao Na 
Published: June 2024

Abstract

Background: The intricate interplay between host genes and intrahepatic microbes is vital in shaping the hepatic microenvironment and contributes significantly to our understanding of nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanisms of disease progression mediated by these interactions remain largely elusive.
Methods: We conducted a comprehensive analysis of 570 liver biopsy transcriptomes from five cohorts, including 72 control, 124 nonalcoholic fatty liver (NAFL), 143 borderline and 231 nonalcoholic steatohepatitis (NASH) samples. Least Absolute Shrinkage and Selection Operator penalized regression and Sparse Canonical Correlation Analysis were utilized to identify host-microbiota interactions and their function.
Results: We observed significant upregulations of key genes involved in mitochondrial organization across all disease stages, while genes related to antigen processing showed abnormal activations in advanced stages like NASH. Additionally, the abundances of intrahepatic microbes Methyloversatilis sp. RAC08 and Ralstonia insidiosadecreased significantly across all NAFLD stages. We identified 5537, 1937, 1485, and 2933 host-microbiota interactions in control, NAFL, borderline, and NASH samples, respectively. Notably, interaction strength showed a decreasing trend, especially during the transition from the borderline stage to NASH. In NAFL and borderline stages, bacteria like Bacillales, Ralstonia insidiosa, and Micromonosporaceae played pivotal roles in enhancing host mitophagy by interacting with genes including SQSTM1, OPTN, and BNIP3L. However, such interaction functional clusters were absent in NASH samples.
Conclusion: Disturbed host-microbiota interactions affecting the mitophagy process can lead to a pro-inflammatory hepatic microenvironment through activation of immune reactions, potentially driving disease progression to NASH.
Optimizing community health workers and non-biomedical approaches to assess the burden of soil-transmitted helminthiasis in a school-aged population in rural Rwanda
Authors: Manzi Anatole , Katz Benjamin , Nguyen Daniel , Bekele Emrakabe , Niyonzima Joseph , Nyiraneza Olive , Hirschhorn Lisa R 
Published: June 2024

Abstract

Background:
Soil-transmitted helminths (STHs) remain a major public health problem in many low- and middle-income countries, especially among children. The conventional methods for diagnosing STHs require well-equipped laboratories and trained personnel, often scarce or inaccessible in rural and remote settings. Algorithmic non-biomedical screening tools are a potential strategy for CHWs to ensure rapid detection and referral of children with possible STH infection. We aimed to evaluate the feasibility of a community health worker-led screening program in rural Rwanda. We also sought to describe the Knot, a model leveraging community health workers (CHWs) as school-based health agents (SBHAs) to facilitate the screening, referral, and follow-up of children with presumptive STH, as well as the engagement of teachers and community members in preventive interventions.
Methods:
We conducted a cross-sectional study among 746 school-aged children in Musanze district, Rwanda, between August 2021 and November 2022. We used Beta CommScreen, an algorithmic non-biomedical screening tool that collects socio-demographic, anthropometric, and symptomatic data, as well as water, sanitation, and hygiene (WASH) indicators, to assess the risk of STH infection. The SBHAs engaged teachers and community members in developing a bundle of interventions, such as deworming campaigns, WASH education, and targeted home visits. We used multivariate logistic regression analysis to identify factors associated with presumptive STH infection. We analyzed the data using Stata version 15.1.
Results:
Of 746 children screened by the SBHA, 322 (43%) reported signs of STH infections, and 220 (29%) were referred to the clinic for treatment, the rest of children (102, 14%) were provided with deworming medication at school. Having a CHW for routine monitoring and not walking barefoot were associated with lower risk of STH symptoms (OR = 0.36, 95% CI: 0.21,0.64) and (OR = 0.49, 95% CI:0.08,3.11), respectively. Not washing hands before eating and after using the toilet were not significantly associated with possible STH infections (OR = 7.40, 95%CI:0.79,68.94) and (OR = 3.82, 95%CI:0.37,39.37). Other factors, including the place of residence and age, were also not associated with STH symptoms.
Conclusions:
We found the CHWs were able to use a simple algorithmic screening tool to identify a high burden of symptoms of possible STH. This CHW-based approach to carry out school-based screening of STH infections builds on the strong CHW system in Rwanda, although strengthening referrals to ensure all symptomatic children receive treatment is needed. Strengthening the connection between schools and community-based health services can further expand disease prevention and treatment, furthering Rwanda’s success in improving health and wellbeing.