bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insights into the biosynthesis of palladium nanoparticles for oxygen reduction reaction by genetically engineered bacteria of Shewanella oneidensisMR‐1
Authors: Li Shihui , Huang Jingwen , Tong Linjun , Li Qingxin , Zhou Haikun , Deng Xiaoting , Zhou Jin , Xie Zhiyong , Liu Xueduan , Liang Yili 
Published: April 2024

AbstractOwing to the increasing need for green synthesis and environmental protection, the utilization of biological organism‐derived carbons as supports for noble‐metal electrocatalysts has garnered public interest. Nevertheless, the mechanism by which microorganisms generate nanometals has not been fully understood yet. In the present study, we used genetically engineered bacteria of Shewanella oneidensis MR‐1 (∆SO4317, ∆SO4320, ∆SO0618 and ∆SO3745) to explore the effect of surface substances including biofilm‐associated protein (bpfA), protein secreted by type I secretion systems (TISS) and type II secretion systems (T2SS), and lipopolysaccharide in microbial synthesis of metal nanoparticles. Results showed Pd/∆SO4317 (the catalyst prepared with the mutant ∆SO4317) shows better performance than other biocatalysts and commercial Pd/C, where the mass activity (MA) and specific activity (SA) of Pd/∆SO4317 are 3.1 and 2.1 times higher than those of commercial Pd/C, reaching 257.49 A g−1 and 6.85 A m−2 respectively. It has been found that the exceptional performance is attributed to the smallest particle size and the presence of abundant functional groups. Additionally, the absence of biofilms has been identified as a crucial factor in the formation of high‐quality bio‐Pd. Because the absence of biofilm can minimize metal agglomeration, resulting in uniform particle size dispersion. These findings provide valuable mechanical insights into the generation of biogenic metal nanoparticles and show potential industrial and environmental applications, especially in accelerating oxygen reduction reactions.
Concept analysis of self‐neglect in the elderly: a hybrid model
Authors: Alimohammadi‐Gusheh Farzaneh , Mohammadi‐Shahboulaghi Farahnaz , Tabrizi Kian Nourozi , Fallahi‐Khoshknab Masoud , Rassouli Maryam 
Published: April 2024

AbstractPurposeClarifying the concept of elder self‐neglect.MethodsResearchers investigated the concept of elder self‐neglect using a hybrid approach, including theoretical, fieldwork, and final analysis phases. After an extensive review of related literature to define the concept of self‐neglect and describe its characteristics, the fieldwork phase was carried out to illustrate its empirical features. Accordingly, it led to the extraction of the elder self‐neglect attributes from the first two phases.FindingsElder self‐neglect includes “subjective and objective high‐risk behaviors pertinent to physical and spiritual health as well as restricted social interactions, disregarding the living environment, and a lack of compliance to personal hygiene routines that the elderly demonstrate deliberately or unintentionally. Various factors can contribute to such behaviors, including individual features, poor physical performance, elderly‐oriented psychological disorders, financial challenges, detrimental stressors, unsuccessful social interactions, inaccessible supportive resources, inadequate educational resources, and inappropriate cultural norms. Consequently, such behaviors result in impaired physical and psychological health status, higher risk of misbehavior, poor quality of life, extra caregiving‐treatment burden, and affected mental security in society.”ConclusionGiven that elder self‐neglect is considered a relatively unknown concept in Iran, the study findings can pave the way for future extensive research in the Iranian context by clarifying the concept. It can play a significant role in developing related tools to design more efficient interventions and improve the quality of nursing care services.Implications for nursing practiceThe elder self‐neglect concept can lead to numerous health‐related disorders among the elderly in society. Nurses cannot deal with an unknown phenomenon without exploring and identifying its exact meaning. It is, therefore, imperative to illustrate the different dimensions of this concept to help create a deep understanding among the nurses and perform timely diagnosis and interventional procedures.
Phenotypic clustering of bipolar disorder supports stratification by lithium responsiveness over diagnostic subtypes
Authors: Scott Katie , O'Donovan Claire , Brancati Giulio Emilio , Cervantes Pablo , Ardau Rafaella , Manchia Mirko , Severino Giovanni , Rybakowski Janusz , Tondo Leonardo , Grof Paul , Alda Martin , Nunes Abraham 
Published: April 2024

AbstractIntroductionThe aim of this study was to determine whether the clinical profiles of bipolar disorder (BD) patients could be differentiated more clearly using the existing classification by diagnostic subtype or by lithium treatment responsiveness.MethodsWe included adult patients with BD‐I or II (N = 477 across four sites) who were treated with lithium as their principal mood stabilizer for at least 1 year. Treatment responsiveness was defined using the dichotomized Alda score. We performed hierarchical clustering on phenotypes defined by 40 features, covering demographics, clinical course, family history, suicide behaviour, and comorbid conditions. We then measured the amount of information that inferred clusters carried about (A) BD subtype and (B) lithium responsiveness using adjusted mutual information (AMI) scores. Detailed phenotypic profiles across clusters were then evaluated with univariate comparisons.ResultsTwo clusters were identified (n = 56 and n = 421), which captured significantly more information about lithium responsiveness (AMI range: 0.033 to 0.133) than BD subtype (AMI: 0.004 to 0.011). The smaller cluster had disproportionately more lithium responders (n = 47 [83.8%]) when compared to the larger cluster (103 [24.4%]; p = 0.006).ConclusionsPhenotypes derived from detailed clinical data may carry more information about lithium responsiveness than the current classification of diagnostic subtype. These findings support lithium responsiveness as a valid approach to stratification in clinical samples.
Midnight siesta: Bimodal temporal activity observed in an endangered marsupial predator
Authors: Moore Harry A. , Diete Rebecca L. , Indigo Naomi L. , Cowan Mitchell A. , Trewella Gavin J. , Nimmo Dale G. 
Published: April 2024

AbstractUnderstanding animal behavioural patterns can provide insight into how populations and communities are adapting to broader environmental shifts. The northern quoll (Dasyurus hallucatus), an endangered marsupial predator, has traditionally been classified as nocturnal. However, evidence is emerging that such simple classifications belie the complexity of animal activity patterns. Using time‐stamped camera trap imagery and fine‐scale accelerometer data, our study explores the diel activity patterns of northern quolls across their range in northern Australia. Contrary to the conventional nocturnal classification, we found that the northern quoll used bimodal activity patterns in four of the five populations examined in this study. Activity and accelerometer data showed two nightly movement peaks, with a distinctive lull around midnight, a pattern similar to one displayed by other marsupial predators. We found no consistent effect of season or lunar phase on temporal activity. Instead, its possible temporal activity patterns are primarily influenced by factors not accounted for here, such as prey availability, climate, predator avoidance, or energy expenditure related to digestion. We suggest further research incorporating these factors will improve our understanding of northern quoll behaviour.
A panel of tetranucleotide STR markers as an alternative approach to forensic DNA identification of wolf and dog
Authors: Hrebianchuk Aliaksandra E. , Parfionava Nastassia S. , Zabauskaya Tatsiana V. , Tsybovsky Iosif S. 
Published: April 2024

AbstractCommercial panels of microsatellite (STR) loci are focused on the use of DNA of the domestic dog (Canis lupus familiaris) and are often inapplicable for genotyping the DNA of the gray wolf (Canis lupus lupus). We propose a CPlex test system, including one hexa‐ and 12 tetranucleotide autosomal STR loci, as well as two sex loci, that is equally efficient in DNA identification of biological samples of the wolf and the dog. Analysis of molecular variance between samples revealed significant differentiation values (FST = 0.0784, p < 0.001), which allows to use the panel to differentiate wolf and dog samples. Population subdivision coefficients (θ‐values) were calculated for each of the 13 STR loci of the developed test system. It was shown that the values of the genotype frequency for dogs and wolves, without and with considering the θ‐value, differ by three orders of magnitude (for dogs 8.9 × 10−16 and 2.1 × 10−14 and for wolves 1.9 × 10−15 and 4.5 × 10−14, respectively). The use of population subdivision coefficients will allow to identify the most reliable results of an expert identification study and the power of exclusion provided by the STR loci of the CPlex test system makes it possible to achieve a reliable level of evidence in forensic DNA analysis of both wolves and dogs. The test system has been validated for use in forensic identification of the dog and wolf based on biological traces found at crime scenes, as well as for individual identification and establishing biological relationship of animals of these species.
Floristic diversity of patches generated by protected Ficus ‘trees outside forests’ in agricultural landscapes in Madagascar
Authors: Rafidison Verohanitra M. , Rakotoarimanana Vonjison , Edmond Roger , Aumeeruddy‐Thomas Yildiz , Carrière Stéphanie M. 
Published: April 2024

AbstractFicus trees play an important role as key species in both ecological and sociocultural networks in Madagascar. This study focused on species of isolated Ficus growing in agricultural areas adjoining a forest corridor linking the Ranomafana and Andringitra National Parks in east‐central Madagascar, with the aim of understanding the structural and floristic characteristics of the vegetation regenerating under these Ficus ‘trees outside forests’. Two main aspects were studied: (1) the characteristics of the habitats under the crown of isolated Ficus species (Ficus tiliifolia, Ficus reflexa and Ficus lutea), and (2) the specific structure and composition of the vegetation under these Ficus trees: minimum area, species richness, floristic regularity, diversity and similarity, biological type, vegetation type, proportion of annual and herbaceous species, and seed dispersal methods. The results indicate that each of these three Ficus species has its own community composition. The vegetation under F. reflexa is a shrubby formation dominated by autochorous and zoochorous species located on high slopes with a minimum area of 6–12 m2. The vegetation under F. lutea is a highly anthropized herbaceous formation dominated by autochorous species located on high slopes at an altitude of 1150–1200 m, with a southwest exposure and a minimum area that ranges from 6 to 9 m2. Under F. tiliifolia, different types of plant formations are found in different topographic positions: herbaceous, shrubby or tree‐like, with different modes of seed dispersal.
Little owls (Athene noctua) shift their diet towards nocturnal beetles in an arid North African area
Authors: Saada Intissar , Hammouda Abdessalem , Romanowski Jerzy , Selmi Slaheddine 
Published: April 2024

AbstractUrban life is associated with dietary shifts in opportunistic predators, such as raptors. This is presumably true in food‐poor environments, such as drylands. We investigated this issue in little owls (Athene noctua) inhabiting an arid southern Tunisian area. Using pellet data, we found that coleopterans accounted for 69% of ingested food items. Controlling for prey availability, this coleopteran‐based diet was more notable in the urban environment compared to rural areas. We suggest that habitat conditions in the urban areas have increased the catchability of nocturnal coleopterans which were then more exposed to predation by little owls than in rural areas.
Rethinking job insecurity research: Challenging the homogeneous, linear, and negative effects of job insecurity
Authors: Jiang Lixin 
Published: April 2024

AbstractThe rise of artificial intelligence is reshaping the future of work, making a discussion on job insecurity both timely and imperative. In this commentary, I critically examine several assumptions presented in Klug et al.'s lead article and propose alternative avenues to advance the field. First, I argue for a nuanced understanding of job insecurity by distinguishing between cognitive and affective dimensions, as well as between quantitative and qualitative aspects. By avoiding oversimplification, we can better capture the complex experiences of job insecurity. Second, I challenge the prevailing notion of job insecurity as solely a hindrance stressor with uniformly negative consequences. Instead, I emphasize its potentially motivating effects under certain conditions and advocate for exploring its curvilinear effects on outcomes. Third, I advocate for the adoption of competing theoretical frameworks to enrich our understanding of job insecurity's implications across multiple levels, especially focusing on outcomes at the team, unit, and organizational levels. Finally, I call for more intervention studies aimed at mitigating job insecurity at its sources and improving the well‐being outcomes of job‐insecure employees. To sum, I highlight the importance of challenging conventional assumptions and fostering innovative approaches in job insecurity research.
Perceived overqualification and subjective career success: Is harmonious or obsessive passion beneficial?
Authors: Luksyte Aleksandra , Carpini Joseph Alexandre 
Published: April 2024

AbstractPerceived overqualification may be positively or negatively related to subjective career success. Integrating person‐environment fit theory with the dualistic model of passion, we propose that both harmonious and obsessive passion may help reconcile misfit perceptions arising from feeling overqualified with implications for subjective career success. We argue the lack of work meaningfulness will explain the proposed buffering effects of work passion. We tested our moderated mediation model across two studies. In Study 1 (N = 422), we demonstrated that surgeons who reported being overqualified and who scored lower on harmonious passion experienced diminished work meaningfulness. Following on, surgeons reported heightened intentions to leave their surgical careers. We constructively replicated these results in a time‐lagged Study 2 (N = 201) that included an additional measure of subjective career success—career performance. Across both Studies 1 and 2, obsessive passion did not moderate the proposed effects. The significant moderating result of harmonious, as opposed to obsessive, passion highlighted the importance of autonomous internalization for work in the achievement of subjective career success for workers who feel overqualified. We discuss the theoretical and practical implications of this research, as well as articulate opportunities for future research.
No observed bidirectional effect between tenofovir diphosphate concentrations and gender‐affirming hormone concentrations among transgender persons switching from tenofovir disoproxil fumarate/emtricitabine to tenofovir alafenamide/emtricitabine for HIV pre‐exposure prophylaxis
Authors: Patel Nimish , Morris Sheldon , Burke Leah , Chow Karen , Pacheco Deedee , Anderson Peter , Stancyzk Frank , Blumenthal Jill 
Published: April 2024

AimsMany transgender and gender diverse (TGD) individuals have expressed concerns about the potential for oral pre‐exposure prophylaxis to affect hormonal concentrations achieved from taking gender‐affirming hormone therapy (GAHT). The purpose of this study was to understand the bidirectional effects between hormone and intraerythrocytic tenofovir diphosphate concentrations when switching from tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) to tenofovir alafenamide/emtricitabine (TAF/FTC) in TGD users/nonusers of GAHT.MethodsThe study evaluated stored blood samples and dried blood spot cards from TGD adults without HIV who took ≥12 weeks of TDF/FTC and then switched to ≥12 weeks of TAF/FTC for pre‐exposure prophylaxis.ResultsThirty‐nine individuals met the study inclusion criteria. Regardless of sex assigned at birth and the use of GAHT, there were no significant differences in hormone concentrations when individuals taking GAHT were taking TDF/FTC and then switched to TAF/FTC. Further, there was no significant difference in intraerythrocytic tenofovir diphosphate concentrations between users and nonusers of GAHT.ConclusionThere are no bidirectional effects between hormone and intraerythocytic tenofovir diphosphate concentrations when switching from TDF/FTC to TAF/FTC in TGD users/nonusers of GAHT.
Barriers to dental utilization among Medicaid‐enrolled young children from primary care practices in Northeast Ohio
Authors: Selvaraj David , Agarwal Neel , Albert Jeffrey M. , Nelson Suchitra 
Published: April 2024

AbstractObjectivesTo evaluate the individual and community factors that contribute to dental utilization among young children on Medicaid utilizing the Anderson Model and the Socio‐Ecological Framework.MethodsThis observational cross‐sectional study was conducted using baseline data (socio‐demographics, clinical dental need) from a cluster‐randomized hybrid effectiveness‐implementation trial among 1021 child–parent dyads recruited from primary care practices across northeast Ohio. The baseline data were then linked to dental Medicaid claims data (categorized as any dental visit, volume, and type in the past 12 months) and ICD‐10 codes from the child's EHR data (individual‐level) together with Dental Health Provider Shortage Area (HPSA) status and Area Deprivation Index (ADI) which were obtained at the neighbourhood‐level using home address of each dyad (community‐level). Multivariable analyses using generalized estimating equations (GEE) accounted for clustering by practice, and models included individual‐level alone, and individual + community‐level factors to evaluate their effects on dental utilization.ResultsMedicaid claims data indicated that among the 1021 children (mean age: 4.3 ± 1.1 years; 54.4% males; 43.8% Black, Non‐Hispanic), a majority of children were seeing the dentist at least once a year by the age of 4 (56.1%). The mean ADI of their neighbourhoods was 109.22 (20.2) and 27.5% lived in a HPSA area. The GEE analyses revealed that individual factors such as older children, parents being married, and continuous Medicaid enrollment were associated with significantly higher dental utilization. Among community factors, being in a HPSA had an OR = 1.53 (CI: 1.03, 2.27) associated with higher dental utilization.ConclusionsBeing in a HPSA was associated with higher dental utilization possibly due to dentists or safety net dental clinics in these areas accepting Medicaid‐eligible children.
A Service‐Led Pragmatic Evaluation of Family Foundations Targeting the Reduction of Perinatal Parent Mental Health Difficulties and Family Conflict in Australia
Authors: Giallo Rebecca , McMahon Grace , Schulz Madison , Fogarty Alison , Seymour Monique , Hosking Casey , Findley Helen , Wallace Carolyn , Bladon Samantha , Feinberg Mark 
Published: April 2024

ABSTRACTA service‐led evaluation of home‐based Family Foundations (FF), a perinatal intervention targeting interparental conflict and mental health difficulties, was conducted in Melbourne, Australia. The aims were to assess (a) pre–post intervention changes, (b) parent satisfaction and (c) intervention fidelity. Participants included 288 families who completed self‐report surveys, and FF clinicians who completed fidelity checklists. Approximately 78% of families who commenced FF completed all 10 sessions. High parent satisfaction and intervention fidelity were reported. For Parent 1s (primarily mothers), there were reductions in symptoms of depression, anxiety and stress, interparental conflict and parenting hostility and increases in co‐parenting support, parenting warmth and parenting self‐efficacy—all associated with small effect sizes. For Parent 2s (primarily fathers), there were reductions in interparental conflict and parenting hostility and an increase in parenting self‐efficacy—also associated with small effect sizes. These findings provide a platform for comprehensive and robust long‐term evaluations of home‐based FF in the future.
USP19 regulates DNA methylation damage repair and confers temozolomide resistance through MGMT stabilization
Authors: Liu Jiaqi , Wang Kaikai , Zhu Qian , Zhang Yixin , Chen Yuping , Lou Zhenkun , Yuan Jian 
Published: April 2024

AbstractObjectiveTo elucidate the relationship between USP19 and O(6)‐methylguanine‐DNA methyltransferase (MGMT) after temozolomide treatment in glioblastoma (GBM) patients with chemotherapy resistance.MethodsScreening the deubiquitinase pannel and identifying the deubiquitinase directly interacts with and deubiquitination MGMT. Deubiquitination assay to confirm USP19 deubiquitinates MGMT. The colony formation and tumor growth study in xenograft assess USP19 affects the GBM sensitive to TMZ was performed by T98G, LN18, U251, and U87 cell lines. Immunohistochemistry staining and survival analysis were performed to explore how USP19 is correlated to MGMT in GBM clinical management.ResultsUSP19 removes the ubiquitination of MGMT to facilitate the DNA methylation damage repair. Depletion of USP19 results in the glioblastoma cell sensitivity to temozolomide, which can be rescued by overexpressing MGMT. USP19 is overexpressed in glioblastoma patient samples, which positively correlates with the level of MGMT protein and poor prognosis in these patients.ConclusionThe regulation of MGMT ubiquitination by USP19 plays a critical role in DNA methylation damage repair and GBM patients’ temozolomide chemotherapy response.