bluuebunny/crossref_metadata_2025_split huggingface dataset:
MAKIAN DALAM BAHASA (DIALEK) MELAYU KUPANG
Authors: Djawa Alex , Djuli Labu 
Published: April 2024

Makian biasanya dilakukan oleh orang terdekat, seperti orang tua kepada anak, anak kepada orang tua, antara anak dengan anak, atau antara teman dengan teman. Makian terjadi karena jengkel, benci dan marah. Makian yang sering digunakan dalam bahasa Melayu Kupang ada yang berbentuk kata, frase, dan klausa. Makian yang berbentuk kata seperti: tolo, puki, anjing, babi. Bentuk kata ulang, seperti: anjing-anjing, babi-babi, kode-kode. Berbentuk kata majemuk, seperti: puki mai, cuki mai, lele hanak. Berbentuk frase, seperti: dasar lonte, dasar pancuri, dasar tartau diri. Karakter yang berbeda dengan bahasa Indonesia, seperti: lu pung mai, lu pung no’o, lu pung tolo boa. Berbentuk klausa, seperti: lu su gila, basong su gila, parampuan bagatal, parampuan lonte, mai pung puki lobang, dan basong pung panta lobang.
The Class I Histone Deacetylase Inhibitor as a Potent Therapeutic Target for Treating Glioblastoma and Mocetinostat as a Novel Inhibitor in the Induction Death of Cancer Cells
Authors: Hameed Khathayer Firas 
Published: April 2024

Epigenetic abnormality is one of the hallmarks of glioblastoma cancer cells. Histone deacetylase (HDAC) modification has a crucial role in epigenetic abnormality, which results in the initiation and progression of glioblastoma cancer cells. The selective HDAC inhibitors are well-known epigenetic regulators and promising anti-cancer agents that target specific HDAC enzymes and inhibit the proliferation of many cancer cells. Selective HDAC inhibitors isoform provides a high efficacy as chemotherapy in inhibiting cancer confirmation compared to non-selective HDAC inhibitors. Additionally, selective HDAC inhibitors suppress Class -I HDAC1, HDAC2, HDAC3, and HDAC11. HDAC class I inhibitors induce apoptosis, differentiation, autophagic death cells, and reactive oxygen species (ROS)- induced cell death, inhibit cell migration, invasion, and angiogenesis in cancer cells, while the normal cells showed more resistance to HDAC class I inhibitors. Mocetinostat (MGCD0103), a benzamide histone deacetylase, is a potent anti-cancer therapy for the treatment of several cancer cell lines and induction of autophagy. It has been approved by The Food and Drug Administration (FDA) for the treatment of Hodgkin lymphoma (HL) cell lines. MGCD0103 is a synthesized and selective HDAC inhibitor that has vigorous inhibitory activity against Class-I and IV HDAC. MGCD0103 is well tolerated and has favorable pharmacokinetic properties, pharmacodynamic profile, and fast absorption within 1 hour after oral administration, long elimination half-life, and sustained HDAC inhibition. Therefore, MGCD0103 is expected to be a promising anti-cancer drug for treating several types of human cancer cells.
Keywords: MGCD0103; Apoptosis; Differentiation; Gliblastoma; HDAC; inhibitors.
Three realms in Du Fu's Metrical Poetry
Authors: Yang Zhao 
Published: April 2024

Du Fu's Metrical Poetry has always been regarded as the standard of Chinese classical metrical poetry. On the basis of the elaboration of its aesthetic characteristics by scholars in the second generation of Song and Qing Dynasty, this paper summarizes the three realms of "Big, Deep and High", which can be regarded as an important door to appreciate the artistry of Du Fu's Metrical Poetry.
Learning Styles and Second Language Acquisition: A Review of Influences, Factors, and Educational Implication
Authors: Lin Xiaoyi 
Published: April 2024

Academia and the public have focused on studies of learning styles in second language acquisition in recent years. Students’ cultural backgrounds can reveal how education and culture affect learning. This paper summarizes the definition and the classification of learning styles and lists a brief review of influence, factors, and educational implications related to learning styles in the field of second language acquisition. The researchers analyzed learning styles are variable and numerous factors affect academic success. Studies show the beneficial correlation between learning styles and academic achievement within an appropriate teaching environment. A strong association exists between an effective learning style and favorable language learning results in students. Simultaneously, variables such as the learners' native language background and their personal traits will impact the selection of their specific learning style. There is a correlation between the variety of learning styles among students and the teaching techniques and aims of teachers in the field of education. An in-depth understanding of students' learning patterns will facilitate the advancement of the teaching profession. Since current evaluations and methods for evaluating students' learning types are questioned, more trustworthy learning style assessments must be developed in future studies.
Pemilihan Moda Transportasi Udara Terhadap Frekuensi Penggunaan Transportasi Udara Bandara Matahora
Authors: Sufrianto Sufrianto , Sudardjat Catrin , Aris Munandar Fikri , Akbar Ade 
Published: April 2024

This research aimed to determine the characteristics of users of transportation modes and to find out the frequency of using air transportation at Matahora Airport. The research method used was quantitative with a descriptive approach, which involved depicting and explaining in detail the issues studied based on the data collected in the field. The data collection technique in this research used a questionnaire, where respondents were asked to answer a number of questions about the characteristics and factors influencing the choice of air transportation. Data analysis was conducted using descriptive data analysis to explain the data obtained through a questionnaire. The research results indicated that the characteristics of mode selection for transportation were based on reasons influencing the selection of modes from a total of 60 respondents. The analysis of the characteristics of air passenger travelers showed the largest percentage in the male gender at 68%, age between 36-45 years at 41%, the highest education level being a bachelor's degree at 62%, self-employed occupation at 36%, the reason for using air transportation being faster travel time at 93%, and the influence of mode selection on the frequency of air transportation use simultaneously at 33.4%. Partially, the factors influencing the choice of air transportation mode on frequency were cost at 26.1%, security at 12.1%, and comfort at 9.1%.
Evaluating The Effect of Arthroscopic Rotator Cuff Repair with Concomitant Subacromial Decompression on 2, 4, and 6 Year Reoperation Rates
Authors: Haft Mark , Pearson Zachary C. , Ahiarakwe Uzoma , Nelson Sarah Y. , Srikumaran Uma 
Published: April 2024

Introduction:
The risks and benefits of including an arthroscopic subacromial decompression (ASD) during arthroscopic rotator cuff repair (RCR) are uncertain. Some studies suggest no difference in revision surgery rates, whereas others have found higher revision surgery rates associated with concomitant ASD. In this study, we compare mid-term revision surgery rates in patients undergoing arthroscopic RCR with or without concomitant ASD.

Methods:
A retrospective cohort analysis was conducted using a national all-payer claims database. Current Procedural Terminology and International Classification of Disease, 10th Revision, codes were used to identify patients who underwent primary arthroscopic RCR with or without ASD in the United States. The primary study outcome was revision surgery at 2, 4, and 6 years. Univariate analysis was conducted on demographic variables (age, sex) and comorbidities in the Elixhauser Comorbidity Index using chi-square and Student t-tests. Multivariate analysis was conducted using logistic regression.

Results:
A total of 11,188 patients were identified who underwent RCR and met the inclusion criteria. Of those, 8,994 (80%) underwent concomitant ASD. Concomitant ASD was associated with lower odds of all-cause revision surgery to the ipsilateral shoulder at 2 years (odds ratio [OR], 0.61; 95% confidence interval [CI], 0.51 to 0.73), 4 years (OR, 0.60; 95% CI, 0.51 to 0.70), and 6 years (OR, 0.59; 95% CI, 0.51 to 0.69). Concomitant ASD was also associated with lower odds of revision RCR at 2 years (OR, 0.68; 95% CI, 0.53 to 0.86), 4 years (OR, 0.63; 95% CI, 0.50 to 0.78), and 6 years (OR, 0.61; 95% CI, 0.49 to 0.76).

Discussion:
Arthroscopic RCR with concomitant ASD is associated with lower odds of all-cause revision surgery in the ipsilateral shoulder at 2, 4, and 6 years. The lower mid-term revision surgery rates suggest benefits to performing concomitant ASD with primary arthroscopic RCR. Continued research on the mid to long-term benefits of ASD is needed to determine which patient populations benefit most from this procedure.

Data availability:
The data that support the findings of this study are available from the corresponding author upon reasonable request.
Terapi Cuci Hidung Dengan Nacl Dapat Meningkatkan Sensitivitas Penciuman Pada Pasien Penyintas Covid-19
Authors: Rizki Putra Pamungkas Muhamad 
Published: April 2024

Introduction: Covid-19 is an infectious disease caused by a newly discovered type of coronavirus. COVID-19 is transmitted during respiratory contacts such as coughing and vomiting. One form of its clinical manifestations interferes with the respiratory system. The process begins with the occurrence of olfactory and taste dysfunction. For example, mechanical blockages that prevent odor from reaching the olfactory nerve can lead to a loss of sense of smell. Washing your nose with NaCl fluid is one of the things that is recommended when infected with COVID-19. Washing the nose is useful to reduce symptoms of anosmia or loss of sense of smell.
Methods: This type of research is using quantitative research, with queasy research experimentation through the One Group Pretest and Posttest Design approach, Sampling techniques using Random sampling which is as many as 17 respondents. The study measure used a smelling instrument of 3 items and each item was rated by the patient from 1 to 10 to assess the patient's impaired life.
Results: Test statistics using the Wilcoxon test. The result of a significant level of olfactory sensitivity with a value p-value of 0.000 which means p-value <0.05, therefore Ho was rejected and Ha was accepted.
Discussion: That there is an effect of giving nasal washing therapy with NaCl to the level of olfactory sensitivity in patients who survive covid 19.
Perbedaan Efektivitas Konsumsi Jus Pisang Ambon Dan Jus Kiwi Terhadap Penurunan Hipertensi Pada Lansia
Authors: Ni Kadek Okta Pramesti Dewi Ni Kadek Okta Pramesti Dewi 
Published: April 2024

Introduction: Elderly is a process experienced by humans from the beginning and naturally proceeds which indicates humans have passed through three stages, namely, children, adults, and the elderly. According to the American Society of Hypertension (ASH) hypertension is a progressive collection of cardiovascular symptoms as a result of other complex and interrelated conditions. Ambon bananas contain a lot of fiber so that potassium, magnesium, and calcium contained in Ambon bananas can be well absorbed by the body so that they can lower blood pressure. Kiwi fruit is a fruit that contains vitamin C and potassium to maintain blood pressure conditions and heart health.
Methods: This type of research uses a quasi-experimental research design using a two group’s pretest-posttest design. The sampling technique used is random sampling. The sample in this study amounted to 30 elderly respondents with hypertension.
Results: Univariate results showed that in the ambon banana juice group before the intervention, 2 people (13.3%) had mild blood pressure, 13 people (86.7%) had moderate blood pressure, after the intervention, 1 person (6.7%) had normal blood pressure, 13 people (86.7%) had mild blood pressure, 1 person (6.7%) had moderate blood pressure. In the kiwi juice group before the intervention, 15 people (100%) had moderate hypertension, after the intervention 8 people (53.3%) had mild hypertension, and 7 people (46.7%) had mild blood pressure. The results of the Wilcoxon bivariate test in the ambon banana group obtained a p-value 0.001 < 0.05, while in the kiwi fruit group p-value of 0.002 < 0.05 means that there is an effect of consumption of ambon banana juice and kiwi juice on reducing hypertension in the elderly. The Mann-Whitney test yielded a p-value of 0.017 < 0.05, then Ha was accepted and Ho was rejected, this indicates that there is a significant difference between the consumption of ambon banana juice and kiwi juice in reducing hypertension in the elderly.
Discussion: There is a difference between consuming ambon banana juice and kiwi juice in reducing hypertension.
CUIDADOR DE IDOSOS: O DESPERTAR PARA SAÚDE MENTAL DE QUEM CUIDA
Authors: Souto Henrique Zouain Dutra do , Gontijo Giulia Camara e Silva , Ferreira Carolina Amaral , Baptista Carolina Voto , Moreira João Victor Santoro , Risi Rafael Maggessi , Lima Renata Cristina de Freitas , Oliveira Danieli Ferreira de Lima , Costa Lucas Tavares , Cruz Pedro Paulo Prata da 
Published: April 2024

INTRODUÇÃO O perfil demográfico brasileiro sofreu profundas transformações nas últimas décadas, tais mudanças fizeram com que a presença da figura do cuidador fosse cada vez mais presente nos lares brasileiros. Apesar da unanimidade com relação aos benefícios do paciente com a presença do cuidador, pouca ou nenhuma atenção foi direcionada à saúde da pessoa que convive e lida quase que diariamente com este paciente. OBJETIVO O objetivo do estudo é identificar os transtornos ligados à saúde mental em cuidadores de idosos formais ou informais. METODOLOGIA Foi realizada uma revisão sistemática da literatura sobre saúde mental de cuidadores de idosos. Os trabalhos foram selecionados no Pubmed e Scielo, utilizando-se as palavraschaves: cuidadores de idosos (caregivers of older adults) e saúde mental (mental health). Foram destacados 15 artigos de um total de 236. Nessa busca foi possível identificar o perfil da figura do cuidador, assim como a associação entre altos níveis de sobrecarga, ocorrência de sentimento de culpa e distúrbios psiquiátricos. DISCUSSÃO E CONCLUSÃO É notório um maior impacto na saúde mental desse grupo de estudos. Esse cenário é alicerçado, pela falta de políticas públicas concretas para amparo e suporte aos cuidadores de idosos, resultando em desafios como falta de instrução, falta de regulamentação da profissão e falta de investimento em políticas públicas específicas. É necessário uma abordagem humanizada, reconhecimento da complexidade das funções dos cuidadores e fortalecimento de estratégias de suporte educacional, político, social, financeiro e psicológico para melhorar a qualidade de vida desses profissionais
NATIONAL SECURITY AND LEGAL NIHILISM
Authors: Марченко Д.Э. 
Published: April 2024

Достаточно недавно была принята Стратегия национальной безопасности Российской Федерации. В работе рассматривается правовой нигилизм и его проявления – экстремизм и терроризм – как главные угрозы национальной безопасности. На фоне разворачивающихся геополитических конфликтов и изменений в экономике количество выявленных преступлений в сфере экстремизма и терроризма растет. Легальные ценности российского государства и права находятся в серьезной опасности. Общество подверглось серьезному расслоению как в имущественном, так и в идеологическом плане. Противостояние в идеологической сфере неизменно приводит к снижению значимости защищаемых государством ценностей. Состояние общества, в котором отсутствуют или существенно снижена, дезорганизована роль правовых ценностей, называется аномией. Государственная политика в сфере устранения угроз национальной безопасности должна быть направлена на недопущение скатывания общества до состояния аномии, а также на устранение ее причин и условий.The paper examines legal nihilism and its manifestations – extremism and terrorism, as the main threats to national security. Against the backdrop of unfolding geopolitical conflicts and changes in the economy, the number of detected crimes in the field of extremism and terrorism is growing. The legal values of the Russian state and law are in serious danger. Society has undergone a serious stratification both in terms of property and ideology. Confrontation in the ideological sphere invariably leads to a decrease in the importance of values protected by the state. The state of the society in which the role of legal values is absent or significantly reduced or disorganized is called anomie. State policy in the field of eliminating threats to national security should be aimed at over-coming the prevention of society's descent into a state of anomie, eliminating its causes and conditions.
WEST SANCTIONS PRESSURE AND SOME DIRECTIONS FOR REFORMING RUSSIAN LEGISLATION
Authors: Новопавловская Е.Е. , Жеребцов В.А. 
Published: April 2024

В статье анализируются некоторые направления санкционного процесса, активно начатого коллективным Западом еще в 2014 году и усилившегося после начала специальной военной операции. Актуальность данной тематики обусловлена тем, что санкции имеют серьезные негативные последствия не только для Российской Федерации в целом, но и для каждого из нас. Санкционная политика Запада справедливо названа Президентом Российской Федерации В. В. Путиным «осознанной долгосрочной стратегией, цель которой состоит в том числе в том, чтобы нанести удар по каждой семье, по каждому гражданину России». В этой связи наша страна вынуждена противостоять политике недружественных государств, реагируя на антироссийские санкции различными мерами правотворческого и правоприменительного характера, о чем идет речь в настоящем исследовании.
The article analyzes some areas of the sanctions process which was actively launched by the collective West back in 2014 and intensified after the start of a special military operation. The relevance of this topic is due to the fact that sanctions have serious negative consequences not only for the Russian Federation as a whole, but also for each of us. The sanction policy of the West was correctly titled by the President of the Russian Federation V. V. Putin, “a conscious long-term strategy, the goal of which is, among other things, to strike at every family, at every citizen of Russia”. In this regard, our country is forced to resist the policies of unfriendly states, responding to anti-Russian sanctions with various law-making and law enforcement measures, which is discussed in this study.
Core competency oriented problem-solving teaching ----Taking "Solving Application Problems with a System of Equations" as an Example
Authors: Li Xiaoling , Li Zhongxuan  
Published: April 2024

The teaching of Mathematical problem-solving is one of the three key teaching points in junior high school mathematics. Solving applied problems through equations (systems) is an important component of the first module of teaching content, "Numbers and Algebra", and holds a very important position. It is a key focus in junior high school mathematics problem-solving teaching. At present, under the premise of the implementation of the new curriculum reform in the field of mathematics in China, based on the recent publication of compulsory education curriculum standards,the teachers of mathematics should focus on cultivating excellent mathematical core literacy among junior high school students, and ensuring that they can independently cope with and solve problems in the math teaching of junior high school. Based on the above background, the author focuses on the newly published mathematics curriculum standards in 2022, and studies the teaching design of "solving application problems for systems of equations". In this paper, we explore the mathematical core literacy elements contained in the teaching of solving applied problems in equations, study the improvement path of mathematical problem-solving teaching, share the teaching design practice and thinking based on core literacy oriented problem-solving teaching, and the important role that this teaching design can play in cultivating students' core literacy .
Didactic model of formation of ecological-digital culture of future teachers in conditions of a holistic information and educational environment
Authors: Аниськин В.Н. , Аниськин С.В. , Богословский В.И. , Добудько Т.В. 
Published: April 2024

На основе опыта исследования проблем формирования и развития экологической культуры студентов педагогического бакалавриата, а также содержательно-адаптирующей интеграции и авторской интерпретации особенностей и подходов к организации изучения экологии, экологического воспитания и просвещения обучающихся в процессе их подготовки к профессиональной деятельности в условиях цифровой трансформации системы образования, предлагается дидактическая модель формирования эколого-цифровой культуры будущих учителей. Педагогическое проектирование и конструирование данной модели выполнены с использованием потенциала информационно-образовательного холизма для интеграции и синергетического объединения эколого-цифровых знаний, умений, навыков и компетенций у студентов-педагогов, в результате которого достигается эффект эмерджентности – генерирования нового системного личностного качества. Определяются дидактические возможности смешанного концентрированного обучения экологии и компьютерным наукам на основе метода учебного погружения с использованием современных цифровых систем и технологий на основе современных и перспективных SMART-средств и устройств, выполняющих одновременно функции средств обучения и объектов изучения.
Based on the experience of researching the problems of the formation and development of ecological culture of undergraduate pedagogical students, as well as content-adaptive integration and the authors interpretation of the features and approaches to organizing the study of ecology, environmental education and enlightenment of students in the process of preparing them for professional activities in the conditions of digital transformation of the education system, A didactic model for the formation of environmental-digital culture of future teachers is proposed. Pedagogical design and construction of this model were carried out using the potential of information and educational holism for the integration and synergistic combination of environmental-digital knowledge, abilities, skills and competencies of student teachers, as a result of which the effect of emergence is achieved – the generation of a new systemic personal quality. The didactic possibilities of mixed concentrated training in ecology and computer science are determined based on the method of educational immersion using modern digital systems and technologies based on modern and promising SMART tools and devices that simultaneously perform the functions of teaching aids and objects of study.
Sem empreendedores não há inovação: a construção de um programa de formação de empreendedores
Authors: Chaves Fernando de Castro , Neto Bezamat de Souza , Siqueira Paulo Henrique de Lima , Souza Erivelto Luís de 
Published: April 2024

O projeto pretende apresentar a opção de uma “capacitação massiva”, tanto de alunos quanto de professores da UFSJ, objetivando adquirir atitudes mais empreendedoras. O método será o da pesquisa-ação cujo trabalho então toma 3 rumos diferentes mas complementares: o primeiro, da pesquisa “Potencial Empreendedor dos Alunos” nos campi da UFSJ; o segundo no levantamento de dados sobre as metodologias adotadas por 2 Instituições de Ensino Superior do Brasil (PUC-RJ e INATEL), bem como da Universidad de Concepción do Chile, para a elaboração de um método próprio a ser adotado na UFSJ, a partir de capacitação de professores da UFSJ; o terceiro, será a organização e a programação de uma capacitação massiva e de forma transversal de alunos da UFSJ.