bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cultura investigativa en la formación del comunicador social. Una revisión científica
Authors: Vega Ríos Reisa Mirella 
Published: June 2024

La comunicación social no evidencia fortalezas significativas en la investigación científica por lo que se hace necesario fomentar y promover la cultura de investigación. El estudio tiene el propósito de realizar una revisión sistemática a la cultura investigativa en la formación de investigadores en comunicación social y analizar los avances y retos, con el objetivo de que se identifiquen experiencias, estrategias, métodos y acciones que puedan replicarse como buenas prácticas. La investigación utilizó el método descriptivo, analítico y el uso de técnicas cualitativas. A partir del estado del arte, se hace una revisión a la literatura académica internacional, regional y local en bases de datos y repositorios académicos a las que se tuvo acceso, de los cuales seleccionamos 15 estudios, los cuales evidencias los conceptos de cultura investigativa y formación en comunicación social de los últimos 5 años (2023-2018). Los hallazgos reflejan la preocupación de las academias, organizaciones e investigadores por la formación en cultura investigativa y se concluye que es necesario implementar y dar seguimiento a la cultura investigativa e integrar un sistema de investigación en la formación de formadores en las universidades y facultades de comunicación social.
Efficacy and harms associated with beta-blockers for cardiotoxicity in cancer patients undergoing chemotherapy: a systematic review and meta-analysis.
Authors: Li Jessica T. , Duddy Amanda MM. , Cardona Michelle , Pasupuleti Vinay , Hernandez Adrian V 
Published: June 2024

IntroductionIn patients with breast cancer and lymphoma, anthracyclines are associated with early and late dose-related cardiotoxicity. We systematically evaluated efficacy and harms of the use of beta-blockers in breast cancer and lymphoma patients undergoing chemotherapy.Material and methodsWe searched five engines, and pre-prints until October 10, 2022, for randomised controlled trials (RCTs) evaluating beta-blockers for anthracycline-associated cardiotoxicity in breast cancer and lymphoma patients. Primary outcomes were all-cause mortality, left ventricular ejection fraction (LVEF), left ventricular end-diastolic and end-systolic diameter (LVEDD, LVESD), peak E’ velocity, E/A ratio, E/e’ ratio, NT-pro BNP levels. Secondary outcome was heart rate. Inverse variance random effect meta-analyses were performed, and we used GRADE methods to assess quality of evidence (QoE).ResultsTwelve RCTs were selected (n=1,794), seven RCTs evaluated carvedilol. Mean ages were 39 to 52 years-old, 88.5% were women; 79.4% had breast cancer, and 11.5% lymphoma. The evidence was very uncertain about the effect of beta-blockers on all-cause mortality (RR 0.87, 95%CI 0.55 to 1.37, 12 RCTs, I2=0%, very low QoE), LVEF (MD 2.73%, 95%CI -0.45% to 5.92%, 12 RCTs, I2=93%, very low QoE), and heart rate (MD -9.14 bpm, 95%CI -15.02 to -3.26, two RCTs, I2=87%, very low QoE) vs. controls. Beta-blockers likely reduced NT-pro BNP levels slightly (MD -15.35 pg/mL, 95%CI -22.39 to -8.31, two RCTs, I2=0%, moderate QoE). There were no effects on other outcomes, all with very low QoE.ConclusionsProphylactic use of beta-blockers for cardioprotection had little to no effect on all-cause mortality, LVEF or cardiac function outcomes in cancer patients undergoing anthracycline therapy.
Utilizing Technology Acceptance Model in Technical and Usability Evaluation of The Developed Tourism SMEs Social Media Analytics Tool
Authors: Madila Shadrack Stephen 
Published: June 2024

The tourism sector is among the most profitable sectors with a high contribution to the world economy. The majority of tourism organisations are operated as small and medium-sized enterprises (SMEs). These tourism SMEs adopted the use of ICT in their businesses. Social media analytics (SMA) is the process of evaluating and analysing social media data and getting insight from it for business decision-making. In this study, the social media analytics tool was developed based on tourism SMEs managers and owner’s requirements. The aim of this study is to utilise technology acceptance model (TAM) to evaluate the developed social media analytics tool for tourism SMEs. The social media analytics tool was developed based on tourism SMEs requirements and followed TAM construct of perceive ease of use and perceive usefulness. The developed tool was hosted and participants were invited to conduct the evaluation process. 10 ICT personnel conducted the technical evaluation of the system while 15 end users of the system participated in usability evaluation. The findings show that the majority of the technical evaluation participants were satisfied with the technical aspect of the developed social media analytics tool. Usability evaluation results show that the participants were satisfied with the ease of use of the tool, the interfaces of the tool and they all agreed that the developed system modules are useful to tourism SMEs and they will recommend the tool to other SMEs managers and owners. The study recommends the use of TAM model in developing and evaluation of the developed IT systems. The technical evaluation aspect seems to be few; hence the study recommends on the future versions of the tools the technical evaluation aspect to be increased during evaluation.
Trends From 2010 to 2019 in Opioid and Nonopioid Pain Management After Total Knee Arthroplasty
Authors: Bahoravitch Tyler , Roberts Max , Zhao Amy , Stake Seth , Ernst Brady , Thakkar Savyasachi C. 
Published: June 2024

Introduction:
As the opioid epidemic enters its third decade, we reflect on how it has affected clinical practice within the orthopaedic community. Recent studies show prolonged opioid use after total knee arthroplasty (TKA) is associated with worse overall health outcomes. This study aims to elucidate trends in pain management after TKA over the past decade.

Methods:
A retrospective analysis was performed using the PearlDiver database from 2010 to 2019. Patients who underwent primary TKA without a history of mental illness, complex pain syndromes, or opioids used 6 months before surgery were selected. Postoperative prescription filling rates of opioid and nonopioid at 30, 90 days, and 1 year from surgery were analyzed. Linear regression analysis and compound annual growth rates (CAGRs) were analyzed from 2010 to 2019, a P value <0.05 being considered significant.

Results:
Between 2010 and 2019, 579,269 patients underwent primary TKA. At 30 days, filling of prescriptions for opioids (CAGR = 3.54%) and nonopioids (CAGR = 15.50%) markedly increased from 2010 to 2019. At 90 days, opioids decreased (CAGR = −4.42%). At 1 year, opioid (CAGR = −10.92%) and nonopioid (CAGR = −2.12%) prescriptions markedly decreased from 2010 to 2019.

Discussion:
This study highlights patterns of decreased opioid prescription rates at 90 days and 1 year postoperatively from 2010 to 2019. Decreasing opioid rates may indicate effectiveness in targeted public health campaigns to curb opioid overuse.
PERAN STRATEGIS BANK SYARIAH DALAM MENGEMBANGKAN USAHA MIKRO KECIL MENENGAH: STUDI KASUS DI KABUPATEN DAN KOTA CIREBON
Authors: Suharto Toto 
Published: June 2024

Penelitian deskriptif ini bertujuan untuk mengidentifikasi peran strategis, tantangan, dan menjelaskan kendala bagi bank syariah dalam melayani usaha mikro dan kecil kelas menengah di kota dan kabupaten. Peran strategis bank syariah dalam pengembangan UMKM terlihat dari kontribusinya dalam memberikan pembiayaan yang bertujuan untuk memperkuat permodalan UMKM sehingga dapat meningkatkan Manajemen dan pengembangan bisnis. Bank syariah menghadapi banyak tantangan dalam pengembangan UMKM. Salah satunya adalah keberadaan bank syariah yang masih dianggap sama dengan bank tradisional. Oleh karena itu, pelaku UMKM masih ragu atau enggan mengajukan pinjaman ke bank syariah. Selain itu, semakin banyak lembaga keuangan lain, seperti BMT dan koperasi syariah, yang dapat memberikan pembiayaan dengan prosedur cepat dan persyaratan sederhana. Ini adalah sesuatu yang tidak bisa dilakukan oleh bank syariah. Bank syariah dapat menerapkan berbagai strategi untuk meminimalisir hambatan yang dihadapi UMKM, terutama dalam hal akses permodalan. Sebab, UMKM bisa berkembang lebih baik jika diberikan kesempatan memperoleh pinjaman di bank syariah.
Raspberry-PI based Design of An Interactive Smart Mirror for Daily Life
Authors: Lyons Joe Reginald , Anicho Ogbonnaya , Secco Emanuele Lindo 
Published: June 2024

The Internet of Things and spatial computing are increasingly popular in today's technological environment. These devices can sometimes produce counterproductive effects, complicating the interaction between non-expert end users and the device itself. In this paper, we propose a simple, user-friendly, and cost-effective configurable smart mirror, which can display usefully relevant real-time information. This system is designed based on a low-cost Raspberry Pi paired with an LCD screen. The system can connect with a personal computer (PC) through the IEEE 802.15 wireless communication protocol. The preliminary results in this paper show the intuitive usability of the device in daily life.
Does the use of double hormone replacement therapy for trauma patient organ donors improve organ recovery for transplant
Authors: Gallegos Eden M , Reed Tanner , Deville Paige , Platt Blake , Leonardi Claudia , Bellfi Lillian , Dufrene Jessica , Chaudhary Saad , Hunt John , Stuke Lance , Greiffenstein Patrick , Schoen Jonathan , Marr Alan , Paramesh Anil , Smith Alison A 
Published: June 2024

BACKGROUND
With an ongoing demand for transplantable organs, optimization of donor management protocols, specifically in trauma populations, is important for obtaining a high yield of viable organs per patient. Endocrine management of brain-dead potential organ donors (BPODs) is controversial, leading to heterogeneous clinical management approaches. Previous studies have shown that when levothyroxine was combined with other treatments, including steroids, vasopressin, and insulin, BPODs had better organ recovery and survival outcomes were increased for transplant recipients.
AIM
To determine if levothyroxine use in combination with steroids in BPODs increased the number of organs donated in trauma patients.
METHODS
A retrospective review of adult BPODs from a single level 1 trauma center over ten years was performed. Exclusion criteria included patients who were not solid organ donors, patients who were not declared brain dead (donation after circulatory death), and patients who did not receive steroids in their hospital course. Levothyroxine and steroid administration, the number of organs donated, the types of organs donated, and demographic information were recorded. Univariate analyses were performed with P < 0.05 considered to be statistically significant.
RESULTS
A total of 88 patients met inclusion criteria, 69 (78%) of whom received levothyroxine and steroids (ST/LT group) vs 19 (22%) receiving steroids without levothyroxine (ST group). No differences were observed between the groups for gender, race, pertinent injury factors, age, or other hormone therapies used (P > 0.05). In the ST/LT group, 68.1% (n = 47) donated a high yield (3-5) of organ types per donor compared to 42.1% (n = 8) in the ST group (P = 0.038). There was no difference in the total number of organ types donated between the groups (P = 0.068).
CONCLUSION
This study suggests that combining levothyroxine and steroid administration increases high-yield organ donation per donor in BPODs in the trauma patient population. Limitations to this study include the retrospective design and the relatively small number of organ donors who met inclusion criteria. This study is unique in that it mitigates steroid administration as a confounding variable and focuses specifically on the adjunctive use of levothyroxine.
Safety and efficacy of Kaffes intraductal self-expanding metal stents in the management of post-liver transplant anastomotic strictures
Authors: Lim Chee , Ng Jonathan , Sarraf Babak , Vaughan Rhys , Efthymiou Marios , Zorron Cheng Tao Pu Leonardo , Chandran Sujievvan 
Published: June 2024

BACKGROUND
Endoscopic management is the first-line therapy for post-liver-transplant anastomotic strictures. Although the optimal duration of treatment with plastic stents has been reported to be 8-12 months, data on safety and duration for metal stents in this setting is scarce. Due to limited access to endoscopic retrograde cholangiopancreatography (ERCP) during the coronavirus disease 2019 pandemic in our centre, there was a change in practice towards increased usage and length-of-stay of the Kaffes biliary intraductal self-expanding stent in patients with suitable anatomy. This was mainly due to the theoretical benefit of Kaffes stents allowing for longer indwelling periods compared to the traditional plastic stents.
AIM
To compare the safety and efficacy profile of different stenting durations using Kaffes stents.
METHODS
Adult liver transplant recipients aged 18 years and above who underwent ERCP were retrospectively identified during a 10-year period through a database query. Unplanned admissions post-Kaffes stent insertion were identified manually through electronic and scanned medical records. The main outcome was the incidence of complications when stents were left indwelling for 3 months vs 6 months. Stent efficacy was calculated via rates of stricture recurrence between patients that had stenting courses for ≤ 120 d or > 120 d.
RESULTS
During the study period, a total of 66 ERCPs with Kaffes insertion were performed in 54 patients throughout their stenting course. In 33 ERCPs, the stent was removed or exchanged on a 3-month interval. No pancreatitis, perforations or deaths occurred. Minor post-ERCP complications were similar between the 3-month (abdominal pain and intraductal migration) and 6-month (abdominal pain, septic shower and embedded stent) groups - 6.1% vs 9.1% respectively, P = 0.40. All strictures resolved at the end of the stenting course, but the stenting course was variable from 3 to 22 months. The recurrence rate for stenting courses lasting for up to 120 d was 71.4% and 21.4% for stenting courses of 121 d or over (P = 0.03). There were 28 patients that were treated with a single ERCP with Kaffes, 21 with removal after 120 d and 7 within 120 d. There was a significant improvement in stricture recurrence when the Kaffes was removed after 120 d when a single ERCP was used for the entire stenting course (71.0% vs 10.0%, P = 0.01).
CONCLUSION
Utilising a single Kaffes intraductal fully-covered metal stent for at least 4 months is safe and efficacious for the management of post-transplant anastomotic strictures.
Effect of Microwaves, Ultrasound, Enzyme, and Lactic Bacteria on Extraction Efficiency of Bioactive Compounds from Agarwood Leaves (Aquilaria spp.)
Authors: Lieu My Dong , Doan Trung Nam , Tran Thi Phuong , Tran Thi Hong Cam , Dang Thi Kim Thuy 
Published: June 2024

Agarwood leaves (Aquilaria spp.) have been shown to benefit human health due to their bioactive compounds. However, studies on extraction methods for these beneficial compounds from agarwood leaves have been poorly reported. Therefore, the present study aimed to investigate the efficiency of extraction methods for such compounds. The studied methods included microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), Viscozyme L treatment, and fermentation by Lactobacillus acidophilus ATCC 4356. The total contents of polyphenols, polysaccharides, saponins, flavonoids, and antioxidant activity were evaluated. The results showed that bioactive compound extraction efficiency differed depending on the treatment methods. Viscozyme L treatment showed the most effective method, followed by MAE treatment and lactic fermentation, and UAE treatments showed the lowest result. The total contents of polyphenols, polysaccharides, saponins, flavonoids, and the antioxidant activity in the case of Viscozyme treatment were 51.81±2.65 mg GAE/g sample; 23.711±1.26 mg GE/g sample; 252.77±4.32 mg OAE/g sample; 7.90±0.72 mg QE/g sample; and 55.1±1.3%, respectively. The results also indicated that each extraction method has its advantages. MAE and UAE treatments caused overheating inside the medium, affecting the antioxidant activity compounds. In the case of the fermentation process, excessive prolonging of the fermentation time also affected the sensitive antioxidant activity compounds released from the plant cells. The lactic fermentation process required the most time to reach extraction efficiency. However, fermentation would provide bioactive compounds and probiotics for health benefits, showing a potential approach for food supplementation.
Sociolínguística e variação: apontamentos teórico-práticos
Authors: Dantas Leila Patrícia Alves , Saraiva Yanara Pessoa 
Published: June 2024

Desde a segunda metade do século XX, os estudos na área da linguagem voltaram-se para questões que ultrapassam os limites internos ou estruturais da língua, buscando evidenciar aspectos linguísticos que envolvam os falantes, o contexto, a interação, a oralidade, dentre outros. Este trabalho está apoiado nos estudos da Sociolinguística, a qual destaca as relações existentes entre língua e sociedade. Lançando o olhar para a heterogeneidade, diversidade e variação da língua portuguesa, a serviço das necessidades sociocomunicativas dos falantes, traçamos como objetivo deste estudo realizar um levantamento bibliográfico sobre algumas das concepções de língua existentes e aquela a que se tem dado ênfase no ensino de língua portuguesa. Nesse caso, trata-se de uma pesquisa de levantamento bibliográfico e natureza descritiva, a partir dos principais pesquisadores da Sociolinguística e do ensino com abordagem variacionista, no Brasil. Diante disso, para o desenvolvimento desse estudo, foram levadas em consideração as contribuições da Linguística e da Sociolinguística quanto à concepção de língua e os estudos da variação linguística, a partir de relevantes pesquisadores da área, como: Labov (1976), Bortoni-Ricardo (2005), Faraco (2008), Bagno (2003), entre outros, ressaltando aspectos cruciais da teoria, como norma, variação e preconceito linguístico. Longe de encerrar a discussão aqui suscitada, mas de abrir caminhos para um debate sobre um ensino e uma pedagogia variacionista, as leituras e reflexões apontam para uma concepção de língua que contempla, de forma clara e incisiva, os fenômenos de variação linguística, de maneira consciente e reflexiva, destacando espaços formais de ensino como o principal locus de construção dessa concepção de linguagem e combate ao preconceito linguístico.
Neither agreement nor pronouns
Authors: Saab Andrés 
Published: June 2024

Baker & Kramer (2018) suggests that the distribution of clitic doubling in Spanish follows from Weak Crossover. Thus, the fact that in accusative clitic doubling bare wh-phrases cannot be doubled (e.g., *¿A quién lo viste? ‘Who did you see?’) is explained by the same reason that explains a standard WCO violation (e.g., *?¿A quién vio su madre? ‘Who did her mother see?’). If this in on the right track, then, accusative doubling clitics must be considered plain pronouns. The fact that the distribution of dative clitic doubling is wider than accusative clitic doubling, allowing, for instance, the doubling of bare wh-phrases (e.g., ¿A quién le diste un libro? ‘Who did you give a book?’), is, consequently, taken by Baker & Kramer as evidence that dative doubling clitics cannot be pronouns, but mere agreement markers. In this reply, I show, mainly based on data from Rioplatense Spanish, that both conclusions are incorrect. Baker & Kramer’s suggestion regarding accusative doubling both overgenerates and undergenerates. What regulates the distribution of doubling clitics in Rioplatense Spanish and beyond is the inflectional makeup of objects. Concretely, direct objects are doubled whenever they bear a [person] feature (Di Tullio et al 2019), whereas indirect objects are doubled by the mere presence of a [D]-feature (Pujalte & Saab 2018). Yet, despite this difference, both are probes for A-movement and predicate-makers at LF, i.e., neither plain pronouns nor mere agreement markers.
Morphology of Female Genitalia of Xylotrechus basifuliginosus Heller, 1926 (Coleoptera: Cerambycidae: Clytini)
Authors: Ramola Gaurav Chand , Singh Arun Pratap 
Published: June 2024

Female genitalia have been largely neglected in studies of genital evolution, perhaps due to the long-standing belief that they are relatively invariable and therefore taxonomically and evolutionarily uninformative in comparison with male genitalia. In the present study, the female genital structure of lesser known beetle, Xylotrechus basifuliginosus was examined for the first time for morphological descriptions using advanced microscopy techniques and dissection methods and compared with its female congener, Xylotrechus smei (Castelnau & Gory). In X. basifuliginosus, the tergite and sternite are generally equal in length. Fully extended genitalia is 3.78mm long from the proximal edge of 9th segment and 0.37mm at its widest.8th abdominal segment is 0.65mm long, 0.36 mm wide whereas eighth abdominal segment is 1.2 times longer than wide, apico-lateral margin, covered with intermix of few short and long setae in X. smei. The genital pocket is 1.36 mm long-scissor like, cylindrical in shape, strongly sclerotized. Spermatheca duct is reduced, “J” shaped just like the genera of Chlorophorus and Plagionotus spp. Spiculum gastrale is 1.34 mm long, thin, slightly thickened at tip and almost three times the length of sternite 8 and ovipositor is 2.19 mm long, 0.85 mm wide, elongated and gradually narrows down to posterior end in X. basifuliginosus whereas in X. smei, spiculum gastrale is 3.43 mm long; ovipositor is with distinct paraproct, gonocoxite and gonostylus and surface of gonostylus is with few setae.