bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge Regarding Pregnancy Induced Hypertension among Pregnant Women Attending in a Tertiary Hospital
Authors: Basnet Sreejana , Gautam Bhattarai Saraswoti Kumari , Panta Ganga 
Published: June 2024

Introduction: Pregnancy induced hypertension is a leading cause of maternal and fetal morbidity and mortality worldwide. It poses risks to both the mother and the baby, associated with premature delivery, growth limitations, placental abruption and even maternal mortality. Therefore, the study aims to find out the level of knowledge regarding pregnancy induced hypertension among pregnant women attending in tertiary hospital.
Methods: A descriptive cross sectional study design with a purposive sampling technique was used to assess the knowledge regarding pregnancy induced hypertension among pregnant women attending antenatal outpatient department Tribhuvan University Teaching Hospital. The total sample size was 195.Face to face interview technique was used to collect the data. Analysis was done by using the Statistical Package for Social Science 16 version using descriptive statistics and inferential statistical test (chi-square test and fisher’s exact test).
Results: Less than one fifth (17.9%) had adequate level of knowledge, less than half (47.7%) had moderately adequate knowledge level and more one third (34.4%) had inadequate knowledge level regarding pregnancy induced hypertension. The level of knowledge was significantly associated with occupation (p=0.019) and source of information (p= 0.000).
Conclusion: This study revealed that only one fifth respondents had adequate knowledge on pregnancy induced hypertension; and significantly associated with occupation. Therefore, awareness raising program need to be conducted in the antenatal clinic to increase the knowledge level of majority of pregnant women.
Gacha Mobile Legend Dalam Pandangan Islam
Authors: Kurniawan Rahmat , Assalimy Muhammad Zaky , Ismail Ahmad Akrom 
Published: June 2024

Penelitian ini bertujuan untuk mengeksplorasi pandangan Islam terhadap Gacha dalam permainan mobile legends, dengan mempertimbangkan aspek hukum, etika, dan sosial.metode analisis kualitatif dengan mengumpulkan dan menganalisis pandangan ulama serta literatur Islam terkait dengan perjudian dan praktik serupa. Hasil analisis menunjukkan bahwa mayoritas ulama menganggap Gacha sebagai bentuk perjudian yang bertentangan dengan prinsip-prinsip Islam. Kesimpulannya,yaitu bahwa dalam pandangan Islam terhadap Gacha mungkin bervariasi, penting bagi pemain Muslim untuk mempertimbangkan dampak moral dan etis dari partisipasi dalam praktik semacam itu, sambil mengacu pada pedoman agama dan nilai-nilai yang dianutnya.
COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE): ITS COMORBIDITY AND OTHER RESPIRATORY PROBLEMS IN SELECTED TERTIARY CARE HOSPITALS OF PESHAWAR, KP
Authors: Haseebullah  , Hassan Karim  , Sobia Afridi  , Sarah Maqsood  , Farhan khan  , Aleena Mushtaq  , Sami ur Rehman  , Yasir Aziz  
Published: June 2024

Background: COPD (Chronic obstructive pulmonary disease) is a chronic inflammatory disease that causes obstructed airflow from the lungs. Many studies have been done to investigate the association of COPD between smokers and non-smokers. Most studies showed that smokers are more prone to COPD; much comorbidity is also associated with COPD such as hypertension, Diabetes etc.
Objectives: To determine the frequency in terms of percentage among smokers and non-smokers, observed the prevalence of comorbidities in COPD, and evaluate general characteristics of COPD in selected tertiary care hospitals of Peshawar.
Methodology: A cross-sectional study was conducted in selected tertiary care hospitals of Peshawar having duration of 1 year (extendible to 1.5 years) from January 2018- January 2019, from pulmonary wards. The random sampling technique was used. The Data was collected through self-prepared questionnaires and analyzed for descriptive statistics using SPSS version 20.
Results: It was seen that COPD, along with coughing, chest tightness and shortness of breath, is more common in patients having a family history of COPD for 1-5 years, while phlegm with wheezing or whistling is more common in patients with COPD for 6-10 years. Comorbidities include hypertension (14.3% in 50 patients), kidney problems (3.2% in 50 patients).
Conclusion: COPD is prevalent in males of age group (41-50 years) with a percentage of (84%). Its major cause is smoking in most of the individuals. Other associated conditions such as hypertension (14.3%), diabetes, asthma, depression, and cardiovascular disorders also contribute to the development of COPD. It can be prevented by cessation of smoking, distance from people with chest infection and taking physical activity.
Keywords: COPD, comorbidity, Respiratory problems
PKM USAHA TERNAK KAMBING DESA JAMPU KABUPATEN SOPPENG
Authors: Dahri Ahmad Thamrin , Setiawan Asri Mulya 
Published: June 2024

Permasalahan utama yang dialami oleh mitra kami yakni usaha ternak kambing milik Bapak Burhanuddin meliputi permasalahan di bidang produksi pakan fermentasi, manajemen usaha serta budidaya ternak.Â Permasalahan bidang produksi pakan fermentasi basah meliputi jumlah atau kuantitas pakan fermentasi yang terbatas dan lamanya proses produksi pakan dikarenakan produksi pakan ternak dilakukan sendiri oleh mitra secara manual. Cara produksi pakan fermentasi yang dilakukan secara manual menyebabkan kuantitas pakan yang dihasilkan menjadi tidak maksimal, selain itu akan lebih banyak waktu yang tersita untuk menghancurkan bahan pakan berupa batang pisang karena ukuran batang pisang yang besarÂ sedangkan alat yang digunakan masih sangat sederhana. Solusi yang ditawarkan adalah : 1. Alat dan mesin produksi pakan ternak agar dapat meningkatkan efektifitas dan efisiensi proses produksi pakan ternak; 2. Pelatihan cara beternak/budidaya (komposisi pakan berkualitas, pemberian vitamin dan vaksin, sanitasi kandang) agar proses penggemukan domba pedaging bisa lebih efektif dan efisien dikarenakan bila nutrisi dan kesehatan domba senantiasa terjaga maka capaian bobot domba standart dapat segera tercapai dalam kurun waktu pemeliharaan ternak yang lebih singkat (sesuai target); 3. Pelatihan manajemen usaha (analisa usaha) dan manajemen pemasaran (strategi pemasaran ternak domba) agar mitra dapat mengelola usaha ternaknya lebih baik, mitra juga dapat melakukan analisa kelayakan usaha ternaknya, dapat menghitung keuntungan bersih yang dapat diperoleh besar BEP (titik impas) serta dapat memperluas daerah pemasaran ternaknya bila kelak jumlah ternak kambing mitra semakin meningkat, 4. Perbaikan kendang. Adapun target luaran yang diharapkan akan dihasilkan oleh kegiatan PKM ini adalah: 1. alat dan mesin produksi pakan fermentasiÂ berupa mesin pencacah batang/bonggol pisang, 2. komposisi pakan berkualitas, pemberian vitamin dan vaksin, sanitasi kandang; 3. manajemen usaha yang baik dan strategi pemasaran ternak domba dengan menggunakan media online.Â Â Selanjutnya publikasi artikel dalam prosiding, publikasi media cetak dan video kegiatan PKM.
Reducing Sugar, Alkaloid and Tannin from Dryopteris dilatata Fractions Modulates Diabetogenic and Oxidative Stress Activity on Alloxan Induced Diabetic Rats
Authors: E. Akpotu Ajirioghene , I. Ghasi Samuel , O. Ike Amalachukwu , F. Akhigbe Omoighele , A. Amadi Micheal , O. J. Ajah Daniel , Funso Funso-Babarimisa, , O. Chukwu Victoria , U. Ukiwa Martins 
Published: June 2024

Active components in medicinal plants possess therapeutic indications in disease states.
Aim: The present investigation evaluated the activity of fraction from Dryopteris dilatata leaves modulating diabetogenic and oxidative stress activity in alloxan-induced diabetic Rats.
Methods: Seventy-two male (135-140)g wistar rats divided into two groups of thirty-six rats each for oral glucose tolerance test and diabetic study. Diabetic induction and oral glucose test (OGTT) was done using standard methods. Each group was divided into six sub-groups (n-6). Group A was normal control, group B diabetic control, group C received metformin 50 mg/kg, group D reducing sugar fraction 800 mg/kg, group E alkaloid fraction 800 mg/kg and group F tannin fraction 800 mg/kg once for OGTT and daily throughout the treatment period (15 days) for diabetic study. Their glucose level was taken at interval of hours for OGTT and five days interval for diabetic group. We assessed the levels of lipid profile (TC, TG, LDL and HDL), lipid peroxidation, endogenous antioxidants in the brain and testis.
Results: Fractions of Dryopteris dilatata caused significant reduction in body weight and blood glucose levels in experimental rats, decreased the levels of TC, TG, LDL, increased HDL, reduced levels of MDA, elevated CAT, GSH and SOD in the brain and testis.
Conclusion: The observed results in this study connotes that fractions of Dd could be used in amelioration of diabetes and its associated complications by reducing bad cholesterol (TC, TG and LDL), increasing good cholesterol (HDL), attenuating the activity of antioxidants in diabetic condition.
Interventional approaches to deep vein thrombosis
Authors: Vedantham Suresh 
Published: February 2012

AbstractThe last decade has seen increased use of aggressive, catheter‐based methods of treating deep vein thrombosis (DVT). In this article, we outline the risks, benefits, and uncertainties surrounding endovascular DVT therapies, describe clinical situations in which endovascular treatment options should reasonably be considered, and update the reader on new outcome data that pertains to catheter‐based DVT interventions. Endovascular thrombolytic therapy is reasonable to perform for selected patients with DVT causing acute limb‐threatening circulatory compromise, acute inferior vena cava occlusion, or acute iliofemoral DVT for the purposes of limb salvage and relief of presenting DVT symptoms, and appears likely to prevent post‐thrombotic syndrome (PTS) in patients with proximal DVT. A multicenter randomized trial, the ATTRACT Study, is currently underway in the United States to determine whether pharmacomechanical catheter‐directed thrombolysis (PCDT) is sufficiently safe and effective to be recommended for routine use in proximal DVT patients. Selected patients with established moderate‐to‐severe PTS in association with an occluded iliac vein or a refluxing saphenous vein may also be amenable to endovascular intervention to reduce venous hypertension, alleviate symptoms, and improve limb function and quality of life. Pending the results of further studies, an individualized approach to patient selection for interventional DVT therapies is recommended. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
Teratogenicity of mycophenolate confirmed in a prospective study of the European Network of Teratology Information Services
Authors: Hoeltzenbein Maria , Elefant Elisabeth , Vial Thierry , Finkel‐Pekarsky Victoriya , Stephens Sally , Clementi Maurizio , Allignol Arthur , Weber‐Schoendorfer Corinna , Schaefer Christof 
Published: February 2012

AbstractAfter maternal exposure to mycophenolate in pregnancy a high number of fetal losses and a specific pattern of birth defects consisting of microtia, cleft lip, and other anomalies have been reported. However, so far, prospective data on pregnancy outcome allowing quantitative risk assessment are missing. We report on 57 prospectively ascertained pregnancies after maternal therapy with mycophenolate (mycophenolate mofetil or mycophenolate sodium) identified by European Teratology Information Services (ETIS) through their risk consultation process. The outcome of these prospective pregnancies was as follows: 16 spontaneous abortions, 12 elective terminations of pregnancy (ETOP) (including two late terminations for multiple malformations consistent with mycophenolate embryopathy), and 29 liveborn infants. The probability of spontaneous abortion was about 45% (95% CI 29 to 66%) estimated using survival analysis technique. Six out of 29 live born infants had major congenital defects: Two with external auditory canal atresia (EACA) (with and without microtia), one with tracheo‐esophageal atresia, one with severe hydronephrosis, one with an atrial septal defect (ASD) and one with a myelomeningocele. Thus, at least four fetuses/infants of our prospective case series had a clinical phenotype consistent with mycophenolate embryopathy. Our results confirm a high incidence of major malformations (26%) after first trimester exposure to mycophenolate. Apart from exposure to mycophenololate, the underlying maternal disease and concomitant medication may also have contributed to the other poor pregnancy outcomes such as a high rate of spontaneous abortions, prematurity (62%), and low birth weight (31%). © 2012 Wiley Periodicals, Inc.
Hormonal and Experiential Predictors of Infant Survivorship and Maternal Behavior in a Monogamous Primate (Callicebus cupreus)
Authors: JARCHO MICHAEL R. , MENDOZA SALLY P. , BALES KAREN L. 
Published: February 2012

To better understand the roles that hormones and experience play in infant survival and maternal behavior in a biparental primate species, we analyzed urinary estrone (E1C) and pregnanediol glucuronide (PdG) from 24 socially housed titi monkey (Callicebus cupreus)females over 54 pregnancies (N = 1,430 samples). Pregnancies were categorized according to whether the infant survived (N = 35) or not (N = 19), and by maternal parity (primiparous:N = 9; multiparous:N = 45). Mothers of infants that survived had a significantly greater drop inPdGfrom the third trimester to the first week postpartum than mothers of infants that did not survive. Multiparous mothers had a greater increase inPdGfrom the first to the third trimester as well as greater increases in theE1C:PdGratio from the first to the third trimester and from the third trimester to the first week postpartum. There were positive relationships between third trimesterPdGand maternal carrying and nursing during the first week postpartum, and between maternal age and carrying during the infant's first month of life. There was a negative correlation between maternal age andPdGduring the third trimester. These results suggest that elevated progesterone during late pregnancy followed by progesterone withdrawal immediately following parturition is associated with greater probability of infant survivorship and maternal behavior in this species, and that older females engage in more postpartum maternal care. Am. J. Primatol. 74:462‐470, 2012. © 2012 Wiley Periodicals, Inc.
Technische Möglichkeiten der Probebelastung von Massivbrücken
Authors: Bretschneider Nick , Fiedler Lutz , Kapphahn Gerd , Slowik Volker 
Published: February 2012

AbstractProbebelastungen massiver, vorwiegend alter Straßenbrücken bilden den Gegenstand einer Diskussion, in die folgende technische Möglichkeiten für die Erzeugung von Testlasten einbezogen werden: Nutzung von hydraulischen Lasterzeugern und Reaktionsrahmen, Anwendung des Belastungsfahrzeuges BELFA sowie Fahrzeugüberfahrten. Zunächst erfolgt die Beschreibung von drei Fallbeispielen. Danach werden Anwendungsgrenzen sowie Vor‐ und Nachteile der verschiedenen Methoden verglichen.Technical possibilities for load tests of concrete and masonry bridges.The experimental safety evaluation of existing concrete and masonry bridges is discussed. There are different technical methods for generating test loads in situ: the utilization of hydraulic actuators and reaction frames, the application of the loading vehicle BELFA, and the measurement of the structural response during vehicle crossing. For each of the three methods, an application example is presented. The technical characteristics and the limitations of the methods are compared.
Aktive Schwingungskontrolle einer Spannbandbrücke mit pneumatischen Aktuatoren
Authors: Bleicher Achim 
Published: February 2012

AbstractNeue Materialien und Technologien erlauben nicht nur Entwurf und Konstruktion ultraleichter und schlanker, sondern auch nachhaltiger Brücken. Mit dem höchstfesten Material kohlenstofffaserverstärkter Kunststoff wurde eine Spannbandbrücke entworfen und gebaut, die mit nur 1 mm Konstruktionshöhe 13 m weit spannt. Um ihre außergewöhnlich hohe Schwingungs anfälligkeit unter Fußgängerverkehr zu reduzieren, wurde eine aktive Schwingungskontrolle entwickelt und an einem Prototypen getestet. Das Konzept zur aktiven Schwingungskontrolle basiert auf dem geregelten Eintrag von Kräften in die Geländerkonstruktion. Zum Einsatz kommen Sensoren, Regelungskonzepte und biologisch inspirierte Aktuatoren, die als aktives System die ersten drei vertikalen Eigenschwingungen der Brücke kontrollieren. Ein wesentliches Element im Entwicklungsprozess des aktiven Systems ist die analytische Modellbildung der Spannbandbrücke, welche dem Entwurf modellbasierter Regelungen zur Kontrolle der Brückenschwingungen dient. Die Effektivität der aktiven Schwingungskontrolle zeigt sich dann durch eine deutliche Reduktion fußgängerinduzierter Beschleunigungen um bis zu 90 % und bestätigt damit auch das Potenzial aktiver Systeme.Multimodal active vibration control of a stress ribbon bridge using pneumatic muscle actuators.New materials and technologies not only allow building ultralight and slender bridges, they also enable the construction of sustainable bridges. By using high‐strength carbon fibre reinforced plastic, a very light and flexible stress ribbon footbridge with a span of 13 m and a structural height of only 1 mm was designed and built in the lab of the Chair of Conceptual and Structural Design at TU Berlin. In order to counteract the high level of pedestrian‐induced vibrations, an active vibration control concept was developed and applied to the prototype. This concept consists of sensors, closed loop controls and biologically inspired actuators. The actuators are embedded into the handrail to control the first three vertical modes of the bridge. One basic element for the development of the active system is the modelling of the bridge to design model‐based controller. The efficiency of the multimodal active vibration control and the potential of active systems are shown by an enormous reduction of pedestrian‐induced accelerations up to 90 %.
Zuschrift zu: Held, M., Gelien, M.: Ein Beitrag zu vereinfachten Berechnungsverfahren für die Heißbemessung von Stahlbetondruckgliedern
Authors: Cyllok Michael , Achenbach Marcus 
Published: February 2012

AbstractZuschrift zu:Held, M., Gelien, M.: Ein Beitrag zu vereinfachten Berechnungsverfahren für die Heißbemessung von Stahlbetondruckgliedern. Beton‐ und Stahlbetonbau, 106 (2011), S. 700–706. doi: 10.1002/best.201100044 Erwiderung der Autoren
Neuronal organization of the hemiellipsoid body of the land hermit crab, Coenobita clypeatus: Correspondence with the mushroom body ground pattern
Authors: Wolff Gabriella , Harzsch Steffen , Hansson Bill S. , Brown Sheena , Strausfeld Nicholas 
Published: February 2012

AbstractMalacostracan crustaceans and dicondylic insects possess large second‐order olfactory neuropils called, respectively, hemiellipsoid bodies and mushroom bodies. Because these centers look very different in the two groups of arthropods, it has been debated whether these second‐order sensory neuropils are homologous or whether they have evolved independently. Here we describe the results of neuroanatomical observations and experiments that resolve the neuronal organization of the hemiellipsoid body in the terrestrial Caribbean hermit crab, Coenobita clypeatus, and compare this organization with the mushroom body of an insect, the cockroach Periplaneta americana. Comparisons of the morphology, ultrastructure, and immunoreactivity of the hemiellipsoid body of C. clypeatus and the mushroom body of the cockroach P. americana reveal in both a layered motif provided by rectilinear arrangements of extrinsic and intrinsic neurons as well as a microglomerular organization. Furthermore, antibodies raised against DC0, the major catalytic subunit of protein kinase A, specifically label both the crustacean hemiellipsoid bodies and insect mushroom bodies. In crustaceans lacking eyestalks, where the entire brain is contained within the head, this antibody selectively labels hemiellipsoid bodies, the superior part of which approximates a mushroom body's calyx in having large numbers of microglomeruli. We propose that these multiple correspondences indicate homology of the crustacean hemiellipsoid body and insect mushroom body and discuss the implications of this with respect to the phylogenetic history of arthropods. We conclude that crustaceans, insects, and other groups of arthropods share an ancestral neuronal ground pattern that is specific to their second‐order olfactory centers. J. Comp. Neurol. 520:2824–2846, 2012. © 2012 Wiley Periodicals, Inc.
Connections of the lateral hypothalamic area juxtadorsomedial region in the male rat
Authors: Hahn Joel D. , Swanson Larry W. 
Published: February 2012

AbstractThe connections of the lateral hypothalamic area juxtadorsomedial region (LHAjd) were investigated in a series of pathway‐tracing experiments involving iontophoretic co‐injection of the tracers Phaseolus vulgaris‐leucoagglutinin (PHA‐L; for outputs) and cholera toxin B subunit (CTB; for inputs). Results revealed that the LHAjd has connections with some 318 distinct gray matter regions encompassing all four subsystems—motor, sensory, cognitive, and behavioral state—included in a basic structure–function network model of the nervous system. Integration of these subsystems is necessary for the coordination and control of emotion and behavior, and in that regard the connections of the LHAjd indicate that it may have a prominent role. Furthermore, the LHAjd connections, together with the connections of other LHA differentiations studied similarly to date, indicate a distinct topographic organization that suggests each LHA differentiation has specifically differing degrees of involvement in the control of multiple behaviors. For the LHAjd, its involvement to a high degree in the control of defensive behavior, and to a lesser degree in the control of other behaviors, including ingestive and reproductive, is suggested. Moreover, the connections of the LHAjd suggest that its possible role in the control of these behaviors may be very broad in scope because they involve the somatic, neuroendocrine, and autonomic divisions of the nervous system. In addition, we suggest that connections between LHA differentiations may provide, at the level of the hypothalamus, a neuronal substrate for the coordinated control of multiple themes in the behavioral repertoire. J. Comp. Neurol. 520:1831–1890, 2012. © 2012 Wiley Periodicals, Inc.
Electron tomographic analysis of synaptic ultrastructure
Authors: Burette Alain C. , Lesperance Thomas , Crum John , Martone Maryann , Volkmann Niels , Ellisman Mark H. , Weinberg Richard J. 
Published: February 2012

AbstractSynaptic function depends on interactions among sets of proteins that assemble into complex supramolecular machines. Molecular biology, electrophysiology, and live‐cell imaging studies have provided tantalizing glimpses into the inner workings of the synapse, but fundamental questions remain regarding the functional organization of these “nano‐machines.” Electron tomography reveals the internal structure of synapses in three dimensions with exceptional spatial resolution. Here we report results from an electron tomographic study of axospinous synapses in neocortex and hippocampus of the adult rat, based on aldehyde‐fixed material stabilized with tannic acid in lieu of postfixation with osmium tetroxide. Our results provide a new window into the structural basis of excitatory synaptic processing in the mammalian brain. J. Comp. Neurol. 520:2697–2711, 2012. © 2012 Wiley Periodicals, Inc.