bluuebunny/crossref_metadata_2025_split huggingface dataset:
P02-378 - Prevalence Of Premenstrual Syndrome And Premenstrual Dysphoric Disorder In Greek Nursery Students
Authors: Karaoulanis S.E. , Mouzas O.D. , Rizoulis A.A. , Angelopoulos N.V. 
Published: June 2010

ObjectivesThis study was designed to provide information on prevalence of premenstrual syndrome and premenstrual dysphoric disorder in Greek nursery students.MethodsPremenstrual symptoms of 125 students (18-22 years old) were assessed by the Premenstrual Symptoms Screening Tool (PSST). The PSST reflects and translates categorical DSM-IV criteria into a rating scale with degrees of severity. The premenstrual symptoms were examined over the course of one menstrual cycle.ResultsThe diagnosis of premenstrual syndrome was confirmed in 26 of 101 women (25.7%) who completed the questionnaire. Nine subjects (8.9%) met criteria for premenstrual dysphoric disorder.ConclusionsThis study indicates a significant prevalence of premenstrual syndrome and premenstrual dysphoric disorder in Greek nursery students. Given the associated impairment in social and occupational functioning seen in premenstrual disorders, these prevalence data provide a strong rationale for enhanced recognition and treatment of the disorders.
P02-388 - Positive Effect Of Escitalopram On Disease Activity In Women With Relapsing-Remitting Multiple Sclerosis
Authors: Mitsonis C. , Zervas I. , Potagas C. , Dimopoulos N. , Psara V. , Gkeka A.E. , Papadimitriou G. 
Published: June 2010

ObjectivesPreliminary studies providing evidence of the neuroprotective effect of SSRIs in patients with Multiple Sclerosis (MS) by improving the metabolic function of axons. The aim of this, open label, randomized, controlled, one year follow-up prospective study was to investigate the effect of escitalopram in the prevention of relapses in women with MS.MethodsForty eight ambulating women with relapsing-remitting MS were randomly assigned to receive 10 mg of escitalopram per day (e-group, N=24) or to continued the study without medication as a control group (c-group, N=24). Neurological examination was performed, by the same neurologist, at baseline and at every regular (4 weeks) and additional visit after a suspect exacerbation.ResultsDuring the study period 55 exacerbations occurred in 33/48 (68.7%) of the patients, and these were confirmed by the study neurologist. E- group patients’ present a mean of 0.8 (SD=0.8) and c-group patients’ a mean of 1.4 (SD=1.0) exacerbations per year. Patients treated with escitalopram present a statistically significant reduction in the mean number of MS relapses respect to the previous year (paired t-test, df=23, t=4.9, p< .001). There was no significant difference between the mean number of MS relapses during the year of the study and the previous year in c-group (paired t-test, df=23, t=-0.68, NS). The cumulative risk for relapse was 2.9 times higher for the controls than for escitalopram-treated patients (95% CI= 1.7- 5.1, p< .001).DiscussionThis study provides evidence that escitalopram tends to decrease MS disease activity in women with MS.
P02-393 - Genders Differences In Opiate-Dependent Patients Undergoing A Replacement Therapy Program In Spain: The Proteus Study
Authors: Roncero C. , Box B. , Miquel L. , Fuste G. , Llaudó J. , Martínez N. , Rodríguez-Cintas L. , Casas M. ,   PROTEUS Group
Published: June 2010

IntroductionThere are 80.000 patients undergoing replacement opiate programs in Spain, mainly methadone. Gender differences and the ratio of dual diagnosis in this population are unknown.ObjectivesTo describe gender differences in the current therapeutic management of opiate-dependent patients undergoing a replacement therapy program in Spain.Methods624 patients from 74 centers in Spain were included between September 2008 and February 2009 in an observational, cross-sectional, multicenter study. Patients were ≥ 18 years, had a diagnosis of opiate dependence according to DSM-IV-TR criteria, were currently scheduled in a replacement therapy program in Spain and were given written informed consent.ResultsOnly 16% of patients were female. Methadone average doses were significantly higher in man (57,59mg ± (SD 46,77) vs 52,81mg ± (SD 50,81) (p< 0.05)). Most women were caretaken by their partner (56.8% vs 34,2%) and man by their parents (61,6% vs 37,8) p< 0,05.Women were found to have significantly more sexual disorders than men (6% versus 2%; p=0.0316); but less delirium, dementia, amnesic and other cognitive disorders (none versus 6%; p=0.0486); schizophrenia and other psychotic disorders (3% versus 13%; p=0.0226); and adaptive disorders (2% versus 9%; 0.0427). No significant differences were found between sexes for other psychiatric comorbidities.ConclusionThe ratio between men and women was close to 5/1, being bigger than that in the general opiate dependent Spanish population. Dual diagnosis rates vary by gender, but not in the number of diagnosis in Axis I or II. Gender differences must be considered when planning dependence services as women.
P02-394 - Psychological Stress And Mental Health Among South Asian Women Brought Up In The Uk
Authors: Rout U. , Rout J. 
Published: June 2010

IntroductionMuch of the research concerning psycho-social stress and mental health within the South Asian community in Britain has centred around new communities settling in England and the associated issues of accommodation, assimilation and integration into the dominant British society. There is a paucity of empirical research concerning the outcomes of psycho-social stress and mental health of British South Asian women in England.ObjectiveTo explore the manifestations of psycho-social stress and mental health in the lives of British South Asian women.MethodsA qualitative research design was employed. A total of 34 British South Asian young women, aged 16-29 years, in formal education and living in the North-West of England, were interviewed. Purposive sampling ensured the demographic characteristics of the sample were broadly representative of young British South Asian women living in the North West. Semi-structured, in-depth interviews were undertaken and analysed using a process of thematic analysis.ResultsThe emerging themes suggest that the outcomes of psycho-social stress in young British South Asian women manifest themselves in three folds: in psychological and physical ways and through negative behavioural practices. Depression and self-harm were the most occurring themes in the sample.ConclusionsThese findings have some fundamental implications for the practice and provision of counselling and support groups for British South Asian young women to help them to manage the psycho-social stress in their lives and improve their mental health. Positive action is required for the development of culturally appropriate services to encourage this group to seek help.
P02-395 - Mental Outcomes Of Tubal Sterilized Contraceptive Methods At Semnanian Women
Authors: Shahbazi Noodeh A. , Ghorbani R. , Behnam B. 
Published: June 2010

IntroductionContraceptive pregnancy methods can cause physical and mental disorders. This study was done to show the mental outcomes of tubal sterilized contraceptive methods (both of tubectomy and vasectomy's husbands) on Semnanian women.Material and methodsIn this study 69 married women with tubectomy or vasectomy husbands’ have been surveyed at three stages: before, six months and a year after that. Subjects have been interviewed by Scle-90-R.FindingsThe most common mental disorders that should be cured:First stagedepression (5.8%), psychosis (2.7%), and paranoid thoughts, phobia, somatic complaints and aggression (each of them 1.4%);Second stagedepression (8.8%), paranoid thoughts, and phobia (each of them 1.7%); andFinal stagedepression (5.3%), psychosis (1.8%), interpersonal sensitivity (1.7%), and aggression (1.4%). the most common disorders that need some consultation: first stage: paranoid thoughts and phobia (each of them 28.4%), somatic complaints (28.2%), interpersonal sensitivity (23%), obsession (20.8%), depression (20.3%), anxiety (19.7%), aggression (18.9%), psychosis (4.1%); second stage: somatic complaints (42.1%), obsession (25.5%), aggression (24.1%), anxiety (22.4%), interpersonal sensitivity (19%), paranoid thoughts and phobia (each of them 17.2%), depression (12.3%) and psychosis (11.9%); and final stage: paranoid thoughts and phobia (each of them 30%), somatic complains (28.1%), obsession (25.9%), depression and anxiety (each of them 21.1%), interpersonal sensitivity (15.3%) and psychosis (7%).ConclusionAlthough mental disorders tubal sterilized contraceptive methods users has not changed more, the high prevalence of them that need consultation confirms the need and necessity to form psychiatric and psychological sections for women at the health centers.
P02-397 - Personality Profile Or Postraumatic Stress Disorder? Personality Characteristics In Women Victim Of Chronic Intimate Partner Violence
Authors: Torres A. , Garcia-Esteve L. , Navarro P. , Tarragona M.J. , Imaz M.L. , Gutiérrez F. , Santos C. , Ascaso C. , Martin-Santos R. , Subirà S. 
Published: June 2010

ObjectiveTo study whether there are personality characteristics that discriminate between IPV women and non-abused control women, taking into account the effect of emotional state (depressive symptoms).MethodA total of 176 women victim of IPV and 193 non-abused control women were assessed with the Dimensional Assessment of Personality Pathology (DAPP-BQ; Livesley, 1990), the Beck Depression Inventory -II (BDI-II; Beck, 1996), and the Index of Spouse Abuse (ISA; Hudson & McIntosh, 1981). Women victim of IPV were recruited from Domestic Violence Centers, and non-abused control women were recruited from Primary Care Centers and Mental Health Services. A two way analysis of variance (IPV * Depression) were used for detecting differences in personality traits taking into account the effect of depression (BDI ≥ 17).ResultsAfter controlling for depression, IPV victims scored higher than control women in submissiveness (F=6.41; p=0.01), cognitive distortion (F=4.35; p=0.04), intimacy problems (F=27.02; p< 0.001), suspiciousness (F=5.02; p=0.03) and self-harm (F=4.93; p=0.03), and lower in rejection (F=14.66; p< 0.001).ConclusionsIPV victims showed high submission, low hostility, intimacy problems, suspiciousness, tendency to depersonalization or derealization, and suicidal ideation and attempts, as a result of chronic abuse. Some of these aspects could be explained by the presence of PTSD, more than by pre-existing personality characteristics. Traumatic and chronic stress can alter functional aspects of the brain and lead to the development of dysfunctional cognitive and behavioral characteristics that may be considered in the psychotherapeutic approach.
P02-399 - Success of Functioning of Family with Childwith Time-lagged Psychical Development, on Mental Condition of Children and Mothers
Authors: Vyetrila T. 
Published: June 2010

ObjectivesWith purpose of establishment of influence of success of functioning of family where child with time-lagged psychical development is educated, on psychical health of its members, 200 families where child grows with violation of psychical development are investigated. On criterion of success of functioning the inspected families were parted on two groups: basic (164 families) - disfunctional and comparisons (36 families) - functional.MethodsAssessment tools: surveillance, clinical and diagnostic interview, objective psychometric scales and test methods to identify the studied trait. Data were subjected to quantitative analysis with subsequent qualitative interpretation and meaningful generalization.ResultsFor all of women from disfunctional families neurotic and highly emotional disorders are diagnosed depressed, anxiously-depressed and fobial spectrum. For children, educated in disfunctional families, negative psycho-emotional state is set with predominance of alarm, depression, nervousness and depression, sense of unscreenedness, outcast and lonelyness.Women from successful families demonstrated absence of psychical violations, and children time-lagged psychical development from families with favourable psychological atmosphere is differed an optimistic emotional background and predominance of sense of protected.ConclusionsThere is necessity of development and introduction in practice, of complex system of medical-psychological rehabilitation of families, educative child with violation of psychical development, including measures, directed on strengthening of health of family and increase of success of domestic functioning. Such complex approach will be given by possibility both to heave up efficiency of rehabilitation of children and promote quality of life of parents of children with violation of psychical development.
P03-387 - Epileptic Seizures Vs Psychogenic Non Epileptic Seizures: Literature Review
Authors: Tzikos A. , Kentigeleni K. , Keskeridou F.G. , Christoudis K. , Samakouri M. , Livaditis M. 
Published: June 2010

ObjectivesThis paper aimsa)to explore the difficulties in differential diagnosis between epileptic crises and psychogenic non epileptic seizures (pseudoseizures),b)to suggest therapeutic guidelines for psychogenic non epileptic seizures. Our purpose is to present a literature review on this subject and to discuss the problems involved.MethodTypical systematic review of recent articles regarding this topic at the internet search engines of PubMed and Scopus. We used the following keywords: psychogenic seizures, psychogenic non epileptic seizures (PNES), pseudoseizures, conversion disorder, dissociative disorder.ResultsA large percentage of the seizures are found to be psychogenic non epileptic. Most of the patients are firstly treated by neurologists and only a percentage of close to 1/3 of these are referred to psychiatrists for further therapy. The differential diagnosis is difficult because most of the patients actually suffer from both epileptic and non epileptic seizures and usually come to the emergency clinics with either. Video EEG and therapeutic hypnosis are considered to be helpful techniques.ConclusionsIn order to treat patients suffering from psychogenic non epileptic seizures there must be a close collaboration between the neurologists, the psychiatrists and the emergency physicians considering both the medication prescribed and the therapeutic guidelines followed.
PW01-02 - Reduced Left Subgenual Anterior Cingulate Cortical Activity During Withdrawal-Related Emotions In Unipolar Depressed Female Patients
Authors: Baeken C. , De Raedt R. , Van Schuerbeek P. , De Mey J. , Vanderhasselt M.A. , Luypaert R. 
Published: June 2010

BackgroundAlthough the subgenual anterior cingulate cortex (Cg25: Brodmann area 25) is an important target area in the treatment of affective disorders, its involvement in the evaluation of emotional salience of visual stimuli during depressed episodes is not quite understood. Research regarding the neurocircuitry in mood disorders suggests an important role of this anatomical region for affective information processing.ObjectiveIn this study, we focused on Cg25 neuronal responses in depressed females using a paradigm in which emotions are elicited without explicit cognitive control, relying on the salient nature of the mood inducing stimuli eliciting approach-related emotions (like happiness) or withdrawal-related emotions (like disgust).MethodsTwelve treatment-resistant melancholic depressed women and 12 age-matched healthy female control subjects were asked to passively view blocks of baby faces when undergoing functional magnetic resonance imaging (fMRI).ResultsCompared to the healthy females, the depressed patients displayed significantly higher bilateral Cg25 neuronal activities in both emotional experiences. Whereas in melancholically depressed women, right-sided Cg25 activity was comparable for both emotional experiences, we found significantly less leftsided Cg25 neuronal activity during the withdrawal-related emotional experience.ConclusionsOur results could indicate that in depressed women the left Cg25 modulates intense visceral emotional responses to aversive visual stimuli. Our observations could help to explain why in unipolar melancholic depression the left Cg25 provides a valid target region for antidepressant treatment strategies, such as deep brain stimulation and anterior cingulotomy and nervus vagus stimulation therapy, which all seem to correlate with decreases in left Cg25 activity.
PW01-06 - Bipolar Mood Disorder - Diagnostic Stability and Evolution: a Retrospective Study of Twenty Years
Authors: Cerullo G. , Saraiva C. , Garrido P. 
Published: June 2010

AimThe purpose of this study is to identify factors associated with diagnostic stability of Bipolar Mood Disorder (BMD) with statistical and clinical interest.MethodsRetrospective cohort study, in which the medical records of 916 individuals admitted to Coimbra University Hospital, between 1989 and 2008 with first diagnostic of BMD, were analysed for the following characteristics: age, gender, occupation, educational level, age at first diagnostic, number and types of hospital admissions, presence of suicide attempts, pharmacological treatments, time between first diagnostic and the new one (Schizophrenia, Delusional Disorder or Dementia), type of cognitive impairment, assessment examinations (TC-CE and EEG) and presence of co-morbidities.The analysed sample was divided in two groups: one that kept the first diagnostic (BMD) and another that later received a different diagnostic.Diagnostic criteria according to International Classification of Diseases- 10th edition.Results4,7% of the total sample received a different diagnostic in a posterior assessment: 41,9% Schizophrenia, 4,7% Delusional Disorder and 53,5% Dementia. The factors were analyzed with traditional statistical methods and Mann-Whitney's test. The authors found five main factors with statistical significance between the two groups, namely, age, age at first diagnostic, total number of admissions and number of admissions for maniac episodes, and educational level.ConclusionsThe aim of the study was achieved. In clinical practice the reported characteristics must receive a special attention in patient's assessment, in order to verify the diagnostic stability and eventual evolution to another diagnostic.
PW01-10 - Columbia University Lithium Archives Project: Bridging the Gap From Laboratory Evidence to Clinical Findings
Authors: Fieve R.R. , Saxena S. , Gilbert M.L. , Orlowski B. 
Published: June 2010

ObjectiveLithium has been used in the successful treatment of bipolar disorders since the 1950's. Advancements in neuroscience show that it has neuroprotective properties suggesting a possible efficacy in stroke, Alzheimer's and dementia. There is also evidence showing lithium protection of neurologic injury by changing GSK-3 inhibition in animals.MethodsThe Lithium Archives Project research design is a retrospective, random paper based chart review of patients with mood disorders. The charts are examined for over 100 variables including demographic, symptom, mood, biochemical, neurologic, and medical items. The current sample of over 700 charts was analyzed by a skilled statistician using standard SPSS statistical software. Mean, standard deviation and significance of cerebrovascular disease, myocardial infarction, brain tumors, stroke, seizures, and eye diseases of patients treated with lithium and patients treated without lithium were compared and analyzed. Multivariate analysis was performed to analyze group (lithium/no lithium) and incidence of disease. The means of disease incidence in the lithium versus non-lithium groups were then charted.ResultsThe Multivariate Analysis of Variance of the current data shows that group is a significant variable in the incidence of diseases analyzed (Pillai's Trace F = 2.926, df = 11,416, p=.004). The patients treated with lithium show less incidence of cerebrovascular disease (p=.053), myocardial infarction (p=.012), seizures (p=.091), eye diseases (p=.011), stroke (p=.014) and brain tumors (p=.072).DiscussionThe current analysis is very promising and indicates that in this patient population, lithium may have played a role in protection from these diseases.
PW01-13 - Neurocognitive Mechanisms of Emotion Regulation in Depression
Authors: Hyett M. , Green M. , Parker G. 
Published: June 2010

ObjectivesNeurocognitive impairments in depression have traditionally been regarded as epiphenomena of the illness. Increasing evidence for the stability of neurocognitive deficits outside of depressive episodes implicates their potential role as mechanisms for emotion dysregulation associated with depressive states. This study thus examined associations between neurocognition and emotion regulation in currently depressed patients.MethodsParticipants were thirty patients presenting with current DSM-IV major depression. Participants completed neurocognitive tasks assessing executive function, attention, working memory, and response control to emotional stimuli. The capacity to implement functional emotion regulation strategies was assessed using additive sub-scales from the ‘Cognitive Emotion Regulation Questionnaire’ (CERQ), while emotion regulation difficulties were assessed using the ‘Difficulties in Emotion Regulation Scale’ (DERS).ResultsNeurocognitive performance was compared between sub-groups of patients identified via median split on combined CERQ and DERS items. Patients reporting greater difficulties in emotion regulation demonstrated impaired sustained attention and response control, and increased reaction time to negative stimuli, in comparison to those reporting fewer difficulties. In addition, patients with better access to functional strategies demonstrated better attentional performance and fewer errors of omission to positive stimuli on the response control task.ConclusionsNeuropsychological impairments in attention and response inhibition may contribute to emotion dysregulation in depressive episodes. By implication, remediation of particular neurocognitive deficits may improve the capacity to implement context-appropriate emotion regulation strategies in affective disorders. Examination of associations between neurocognitive impairment and emotion dysregulation outside of acute illness episodes is necessary to determine the relevance of these associations for illness development.