bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningkatkan Pengetahuan Kesiapsiagaan Bencana Pada Warga di Dusun Beruk Jatiyoso Karanganyar
Authors: Yuliana Nuriyah , Estiningtyas Estiningtyas , Wulandari Fitri , Khotimah Damayyanti Nur 
Published: May 2024

Kesiapsiagaan bencana berfungsi untuk memicu agar masyarakat lebih paham tentang bencana dan masyarakat bisa menciptakan ketangguhan dan kesiapsiagaan bencana. Permasalahan mitra berdasarkan hasil wawancara yaitu masih minimnya kesiapsiagaan bencana yang ada di Dusun Ngantirejo, Beruk, Jatiyoso. Dampak kurangnya kesiapsiagaan bencana yang dimiliki oleh relawan dan warga yang ada didaerah tersebut mengakibatkan kerugian yang besar terutama material ketika terjadi bencana di daerah tersebut. Tujuan yang dicapai pada PKM ini diantaranya: meningkatnya kemampuan kesiapsiagaan masyarakat tentang bencana tanah longsor. Metode yang dilakukan dengan melakukan identifikasi kesiapsiagaan warga setempat, sosialiasi dan simulasi tentang kesiapsiagaan bencana. Hasil kegiatan peningkatakan kesiapsiagaan bencana yaitu hasil studi pendahuluan rata-rata kesiapsiagaan bencana dalam kategori cukup 51 orang, belum ada titik assembling dan jalur evakuasi, masih minimnya pemahaman tentang penanganan korban bencana dengan masalah gangguan sistem muskuloskeletal. Evaluasi kegiatan peningkatan pengetahuan kesiapsiagaan bencana efektif dibuktikan dengan adanya peningkatan pengetahuan kesiapsiagaan bencana sebanyak 66 dari 80 warga memiliki pengetahuan kesiapsiagaan kategori baik, tersedianya jalur evakuasi di Desa Beruk, adanya titik assembling, denah peta kerawanan bencana dan titik rawan bencana longsor.
Literasi Restoratif Justice (Keadilan Restoratif) Kepada Organisasi Kepemudaan
Authors: Taqiuddin Habibul Umam , Mulianah Baiq 
Published: May 2024

Restorative justice (keadilan restorative) berakar dari nilai-nilai tradisional dalam masyarakat tradisional seperti nilai keseimbangan, harmonisasi serta kedamaian dalam masyarakat. Oleh karena itu di beberapa negara tercatat bahwa lembaga peradilan adat tetap dipertahankan sebagai sarana bagi masyarakat untuk menyelesaikan sengketa atau permasalahan yang dialaminya termasuk di dalamnya perkara pidana agar pelaku, korban dan masyarakat serta tokoh masyarakat dirasakan lebih memberikan rasa keadilan masyarakat. Tujuan dan manfaat kegiatan pengabdian kepada masyarakat ini adalah sebagai berikut: 1) untuk memberikan pemahaman konsep restorative justice (keadilan restoratif) kepada organisasi kepemudaan, 2) untuk menggerakan tokoh organisasi kepemudaan agar berperan sebagai penengah (mediator) dalam penyelesaian sengketa di luar pengadilan. Metode pelaksanaan kegiatan literasi restoratif justice (keadilan restoratif) kepada Organisasi Kepemudaan dalam bentuk diskusi interaktif. Berdasarkan kegiatan ang telah dilakukan dapat diambil kesimpulan antara lain sebagai berikut: pertama, Para peserta sangat antusias dalam setiap materi yang diberikan, karena berhubungan langsung dengan persoalan di lapangan terkait dengan penyelesaian sengketa melalui restorative justice (keadilan restoratif). kedua Para peserta mulai memahami peran tokoh pemuda dalam penyelesaian melalui restorative justice (keadilan restoratif). Adapun saran yang ingin diberikan tim pelaksana kegiatan pengabdian kepada masyarakat ini adalan agar penyelesaian sengketa di luar pengadilan lebih optimal, maka sebaiknya perlu dilibatkan tokoh masyarakat terutama tokoh pemuda dalam proses penyelesaian sengketa melalui pendekatan restorative justice (keadilan restoratif).
Stimmverbote im faktischen AG‑Konzern bei Sonderprüfung und Geltendmachung von Ersatzansprüchen — Zugleich Besprechung des Urteils des BGH v. 28.11.2023 – II ZR 214/21, AG 2024, 201, und Erwiderung auf Mock, AG 2024, 193
Authors: Kiefner Alexander , Krumm Karsten , Eichhorn Philip 
Published: May 2024

Zusammenfassung
Insbesondere in Konstellationen mit einem beherrschenden Großaktionär (faktischer AG‑Konzern) kommt bei Beschlussfassungen der Hauptversammlung über eine Sonderprüfung oder über die Geltendmachung von Ersatzansprüchen nebst Bestellung eines besonderen Vertreters der Abgrenzung beider Institute und der Reichweite von Stimmverboten eine entscheidende und höchst praxisrelevante Bedeutung zu. Zu beiden Aspekten hat der BGH im Sinne einer weiteren Stärkung des besonderen Vertreters vor kurzem Stellung bezogen und hierfür jüngst auch ersten Zuspruch von Mock erhalten. Dies ist Anlass genug, das Verhältnis von Sonderprüfung und Geltendmachung von Ersatzansprüchen im Konzern kritisch zu vermessen und die Frage aufzuwerfen, ob die Grenzen der Rechtsfortbildung und Analogiebildung nicht überdehnt werden.
Normalizing cDNA Libraries
Authors: Bogdanova Ekaterina A. , Shagina Irina , Barsova Ekaterina V. , Kelmanson Ilya , Shagin Dmitry A. , Lukyanov Sergey A. 
Published: April 2010

AbstractThe characterization of rare messages in cDNA libraries is complicated by the substantial variations that exist in the abundance levels of different transcripts in cells and tissues. The equalization (normalization) of cDNA is a helpful approach for decreasing the prevalence of abundant transcripts, thereby facilitating the assessment of rare transcripts. This unit provides a method for duplex‐specific nuclease (DSN)–based normalization, which allows for the fast and reliable equalization of cDNA, thereby facilitating the generation of normalized, full‐length‐enriched cDNA libraries, and enabling efficient RNA analyses. Curr. Protoc. Mol. Biol. 90:5.12.1‐5.12.27. © 2010 by John Wiley & Sons, Inc.
Extraction of Proteins from Formalin‐Fixed, Paraffin‐Embedded Tissue Using the Qproteome Extraction Technique and Preparation of Tryptic Peptides for Liquid Chromatography/Mass Spectrometry Analysis
Authors: Geoui Thibault , Urlaub Henning , Plessmann Uwe , Porschewski Peter 
Published: April 2010

AbstractThis unit provides a robust, reliable, and easy‐to‐use kit‐based method for extraction of intact, non‐degraded proteins from formalin‐fixed, paraffin‐embedded (FFPE) tissue, and their subsequent use for analysis by liquid chromatography/mass spectrometry (LC/MS). After deparaffinization, proteins are extracted from unstained sections of FFPE rat liver tissue. After a simple cleanup step using organic extraction, the sample is transferred into a buffer optimized for trypsin digestion of the extracted proteins. Subsequently, LC/MS is used to identify the proteins that gave rise to the tryptic peptides. Comparing formalin‐fixed and frozen tissues, good correlation is observed in the mass spectrometric pattern attributable to the tryptic peptides and number of identified proteins. Since FFPE tissues are generally available in clinical practice, this method can be used to analyze biomarkers in different pathological situations (e.g., healthy vs. diseased). The method can also be used for protein extraction from fresh‐frozen tissue. Curr. Protoc. Mol. Biol. 90:10.27.1‐10.27.12. © 2010 by John Wiley & Sons, Inc.
Critical Aspects in Analysis of Cellular DNA Content
Authors: Darzynkiewicz Zbigniew 
Published: April 2010

AbstractThis unit covers general aspects of DNA content analysis and provides introductory or complementary information to the specific protocols of DNA content assessment in this chapter. It describes principles of DNA content analysis and outlines difficulties and pitfalls common to these methods. It also reviews methods of DNA staining in live, permeabilized, and fixed cells, and in cell nuclei isolated from paraffin‐embedded tissues, as well as the approaches to stain DNA concurrently with cell immunophenotype. This unit addresses factors affecting accuracy of DNA measurement, such as chromatin features restricting accessibility of fluorochromes to DNA, stoichiometry of interaction with DNA, and “mass action law” characterizing binding to DNA in relation to unbound fluorochrome concentration. It also describes controls to ensure accuracy and quality control of DNA content determination and principles of DNA ploidy assessment. Because many aspects of DNA content analysis are common to protocols in UNITS 7.3, 7.6, 7.16, 7.20, 7.23, & 7.25, certain parts of this unit provide information redundant with commentaries in these units. Curr. Protoc. Cytom. 52:7.2.1‐7.2.8. © 2010 by John Wiley & Sons, Inc.
Liquid phase diffusion of branched alkanes in silicalite
Authors: Lettat Kader , Jolimaitre Elsa , Tayakout Mélaz , Tondeur Daniel 
Published: April 2010

AbstractThis work provides a new mass transfer model based on the Maxwell–Stefan theory, especially adapted to represent adsorbed phase multicomponent diffusion at high‐adsorbent loading. In our model—contrarily to the well‐known model developed by Krishna et al. (Chem Eng Sci. 1990;45:7:1779–1791; Gas Sep Purif. 1993;7:91–104; J Phys Chem B. 2005;109:6386–6396)—the hypothesis that the micropores are saturated does not imply a dependency between the adsorbed phase diffusion coefficients. Experimental liquid phase breakthrough curves of 2‐methylpentane (2MP), 3‐methylpentane (3MP), 2,3‐dimethylbutane (23DMB), and 2,2‐dimethylbutane (22DMB) were measured at 458 K in silicalite. The self‐diffusion coefficients and Langmuir parameters of the different species were determined using binary exchange breakthrough curves. The Maxwell–Stefan diffusion coefficients obtained for the different isomers are in the order D3MP,nc+1 > D2MP,nc+1 ≫ D23DMB,nc+1, and vary between 4 × 10−15 m2 s−1 for 3MP to 6 × 10−16 m2 s−1 for 23DMB. The 22DMB diffusion coefficient is so low that it could not be estimated (the quantity of 22DMB entering silicalite during the experiment is not significant). The model was then validated by comparing experimental breakthrough curves at different feed concentrations and simulations using the independently estimated parameters. Even though the diffusion coefficients of the different isomers vary by one order of magnitude, the agreement between simulated and experimental curves is very satisfactory, showing the good predictive power of our model. © 2010 American Institute of Chemical Engineers AIChE J, 2011
First principle‐based simulation of ethane steam cracking
Authors: Sabbe Maarten K. , Van Geem Kevin M. , Reyniers Marie‐Françoise , Marin Guy B. 
Published: April 2010

AbstractA consistent set of ab initio‐based kinetic and thermodynamic data is applied for the simulation of an ethane steam cracking furnace. The thermodynamic data are calculated using accurate quantum chemical CBS‐QB3 calculations including corrections for hindered internal rotation. The kinetics are obtained from CBS‐QB3‐based group additive models. With these thermodynamic and kinetic data, simulations for pilot and industrial ethane steam cracking reactors over a wide range of process conditions are performed. It is shown that, without adjusting any parameter, the main product yields can be predicted within 15% rel. of the experimentally observed cracking yields. This indicates the tremendous potential of integrating ab initio methods with engineering models for accurate reactor simulations. © 2010 American Institute of Chemical Engineers AIChE J, 2011
Challenges in clinical interpretation of microduplications detected by array CGH analysis
Authors: Stankiewicz Pawel , Pursley Amber N. , Cheung Sau Wai 
Published: April 2010

AbstractDue to the lack of robust diagnostic methods and limited resolution of conventional microscopy, submicroscopic genomic duplication copy number variants (CNVs) have been long underascertained. The development of array CGH has enabled detection of microduplications with nearly the same sensitivity as microdeletions and thus allowing them to be routinely identified throughout the human genome. However, in contrast to microdeletions, clinical interpretation of microduplications more often presents a diagnostic dilemma, as the functional impact of these genomic alterations is not well understood. Microduplications are especially difficult to interpret when they encompass several genes or a portion of a gene. Determining their significance involves investigative teamwork between both the diagnostic laboratory and the clinician. We present the steps for interpreting the clinical significance of microduplications and representative examples of these challenging cases. © 2010 Wiley‐Liss, Inc.
In their own words: Reports of stigma and genetic discrimination by people at risk for Huntington disease in the International RESPOND‐HD study
Authors: Williams Janet K. , Erwin Cheryl , Juhl Andrew R. , Mengeling Michelle , Bombard Yvonne , Hayden Michael R. , Quaid Kimberly , Shoulson Ira , Taylor Sandra , Paulsen Jane S. ,   the I‐RESPOND‐HD Investigators of the Huntington Study Group
Published: April 2010

AbstractGenetic discrimination may be experienced in the day‐to‐day lives of people at risk for Huntington disease (HD), encompassing occurrences in the workplace, when seeking insurance, within social relationships, and during other daily encounters. At‐risk individuals who have tested either positive or negative for the genetic expansion that causes HD, as well as at‐risk persons with a 50% chance for developing the disorder but have not had DNA testing completed the International RESPOND‐HD (I‐RESPOND‐HD) survey. One of the study's purposes was to examine perceptions of genetic stigmatization and discrimination. A total of 412 out of 433 participants provided narrative comments, and 191 provided related codable narrative data. The core theme, Information Control, refers to organizational policies and interpersonal actions. This theme was found in narrative comments describing genetic discrimination perceptions across employment, insurance, social, and other situations. These reports were elaborated with five themes: What They Encountered, What They Felt, What Others Did, What They Did, and What Happened. Although many perceptions were coded as hurtful, this was not true in all instances. Findings document that reports of genetic discrimination are highly individual, and both policy as well as interpersonal factors contribute to the outcome of potentially discriminating events. © 2010 Wiley‐Liss, Inc.
LINGO1 is not associated with Parkinson's disease in German patients
Authors: Klebe Stephan , Thier Sandra , Lorenz Delia , Nothnagel Michael , Schreiber Stefan , Klein Christine , Hagenah Johann , Kasten Meike , Berg Daniela , Srulijes Karin , Gasser Thomas , Deuschl Günther , Kuhlenbäumer Gregor 
Published: April 2010

AbstractEssential tremor (ET) and Parkinson's disease (PD) are the most common movement disorders and show clinical, genetic, and pathophysiological overlap. Single‐nucleotide polymorphisms (SNPs) in the leucine‐rich repeat (LRR) and immunoglobulin (Ig) domain‐containing, Nogo receptor‐interacting protein gene (LINGO1) are associated with ET. LINGO1 is overexpressed in the substantia nigra (SN) of PD patients and inhibition of LINGO1 confers neuroprotection in a rodent model of PD. In this study we test the hypothesis whether SNPs in the LINGO1 gene that are associated with ET are also associated with PD. Three large German case–control samples from Kiel, Lübeck, and Tübingen (total: 1,798 cases and 1,482 controls) were genotyped for the three LINGO1 SNPs associated with ET. Association was assessed using allele‐ and genotype‐based tests in each of the three samples separately, in the combined sample, and in subsets of patients with early‐onset PD (<50 years) and of patients with a positive family history of PD. Neither of the three samples alone nor the combined sample showed evidence for association between LINGO1 SNPs and PD. The allele‐based test showed a trend toward nominal association for all three SNPs in the Kiel sample. The subsets with early‐onset PD or a positive family history did also not reveal evidence for association. SNPs in the LINGO1 gene associated with ET could not be shown to be associated with PD in our study population, despite a postulated overlap between both diseases. © 2010 Wiley‐Liss, Inc.
Analysis of the Micro‐RNA‐133 and PITX3 genes in Parkinson's disease
Authors: de Mena Lorena , Coto Eliecer , Cardo Lucía F. , Díaz Marta , Blázquez Marta , Ribacoba René , Salvador Carlos , Pastor Pau , Samaranch LLuis , Moris Germán , Menéndez Manuel , Corao Ana I. , Alvarez Victoria 
Published: April 2010

AbstractMicroRNAs are small RNA sequences that negatively regulate gene expression by binding to the 3′ untranslated regions of mRNAs. MiR‐133b has been implicated in Parkinson's disease (PD) by a mechanism that involves the regulation of the transcription factor PITX3. The variation in these genes could contribute to the risk of developing PD. We searched for DNA variants in miR‐133 and PITX3 genes in PD patients and healthy controls from Spain. We found common DNA variants in the three miR‐133 genes. Genotyping of a first set of patients (n = 777) and controls (n = 650) showed a higher frequency of homozygous for a miR‐133b variant (−90 del A) in PD‐patients (6/575; 1%) than in healthy controls (0/650) (P = 0.03). However, this association was not confirmed in a second set of patients (1/250; 0.4%) and controls (2/210; 1%). No common PITX3 variants were associated with PD, although a rare missense change (G32S) was found in only one patient and none of the controls. In conclusion, we report the variation in genes of a pathway that has been involved in dopaminergic neuron differentiation and survival. Our work suggests that miR‐133 and PITX3 gene variants did not contribute to the risk for PD. © 2010 Wiley‐Liss, Inc.
PCM1 and schizophrenia: A replication study in the Northern Swedish population
Authors: Moens Lotte N. , Ceulemans Shana , Alaerts Maaike , Van Den Bossche Maarten J.A. , Lenaerts An‐Sofie , De Zutter Sonia , Norrback Karl‐Fredrik , Adolfsson Rolf , Del‐Favero Jurgen 
Published: April 2010

AbstractPrevious studies implicated centrosomal dysfunction as a source of various neuropsychiatric disorders, including schizophrenia (SZ). Two recent reports [Gurling et al., 2006; Datta et al., 2008. Mol Psychiatry] described an association between polymorphisms in the PCM1 gene and SZ in a UK/Scottish population. In this study, we aimed to replicate these findings in a Northern Swedish association sample of 486 research subjects with SZ and 512 unrelated control individuals. We genotyped 12 previously described SNP markers and carried out haplotype analyses using the same multi‐marker haplotypes previously reported. Though we could not replicate the association with SNPs rs445422 and rs208747, we did observe a significant protective association with intronic SNP rs13276297. Furthermore, we performed a meta‐analysis comprising 1,794 SZ patients and 1,553 controls, which confirmed the previously reported association with rs445422 and rs208747. These data provide further evidence that PCM1—though certainly not a major risk factor in the Northern Swedish population—cannot be ruled out as a contributor to SZ risk and/or protection, and deserves further replication in larger populations to elucidate its role in disease etiology. © 2010 Wiley‐Liss, Inc.
Electrical properties and morphology of carbon black‐filled HDPE/EVA composites
Authors: Yang Quan‐Quan , Liang Ji‐Zhao 
Published: April 2010

AbstractThe sensitive effect of weight ratio of the high‐density polyethylene (HDPE)/ethylene‐vinylacetate copolymer (EVA) on the electrical properties of HDPE/EVA/carbon black (CB) composites was investigated. With the EVA content increasing from 0 wt % to 100 wt %, an obvious change of positive temperature coefficient (PTC) curve was observed, and a U‐shaped insulator‐conductor‐insulator transition in HDPE/EVA/CB composites with a CB concentration nearby the percolation threshold was found. The selective location of CB particles in HDPE/EVA blend was analyzed by means of theoretical method and scanning electron micrograph (SEM) in order to explain the U‐shaped insulator‐conductor‐insulator transition, a phenomenon different from double percolation in this composite. The first significant change of the resistivity, an insulator‐conductor transition, occurred when the conductive networks diffused into the whole matrix due to the forming of the conductive networks and the continuous EVA phase. The second time significant change of the resistivity, a conductor‐insulator transition, appeared when the amorphous phase is too large for CB particles to form the conductive networks throughout the whole matrix. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Synthesis and gas permeability of membranes of silyl‐substituted poly(p‐phenylenevinylene)s
Authors: Sakaguchi Toshikazu , Koide Yohei , Hashimoto Tamotsu 
Published: April 2010

Abstractp‐Bis(bromomethyl)benzene with silyl groups [SiMe3(2a), SiEt3(2b), SiMe2‐t‐Bu (2c), SiMe2‐n‐Bu (2d), SiMe2‐n‐C8H17 (2e), SiMe2‐n‐C18H37 (2f)] were polymerized by a modified Gilch route to afford silyl‐substituted poly(p‐phenylenevinylene)s (3a–f). The polymer containing SiMe3 groups (3a) was insoluble in any solvents, while the other polymers (3b–f) were soluble in organic solvents. They had relatively high molecular weight over 3.6 × 104, and gave free‐standing membranes by solution casting method. According to thermogravimetric analysis (TGA), the silyl‐substituted poly(p‐phenylenevinylene)s showed high thermal stability (Td ≥ 300°C). The oxygen permeability coefficients of membranes of the silyl‐substituted poly(p‐phenylenevinylene)s (3b–f) were in the range of 3.5–12 barrers, and the poly(p‐phenylenevinylene)s with long alkyl silyl groups, 3e and 3f, exhibited the highest gas permeability among them. This is the first report on gas permeability of poly(p‐phenylenevinylene)s. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Chain extension of poly(ethylene terephthalate) with bisphenol‐A dicyanate
Authors: Zhang Yanjun , Zhang Chen , Li Hangquan , Du Zhongjie , Li Congju 
Published: April 2010

AbstractChain extension of poly(ethylene terephthalate) (PET) with bisphenol‐A dicyanate (BADCy) was studied using an internal mixer under reactive blending conditions. The reaction between PET and BADCy was confirmed by Fourier transform infrared (FTIR) and chemical titration. With increasing amount of BADCy introduced, the modified PET gave rise to higher torque during stirred in an internal mixer, higher viscosity (η′), and higher storage modulus (G′). Measurement of intrinsic viscosity showed that BADCy indeed extended the molecular weight of PET. DSC analysis represented that Tm and Tc of the modified PET were shifted to low temperatures. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
In situ ESR response to temperature evolution of styrene/dibenzoyl peroxide/Di‐TEMPO biradical system
Authors: Szydłowska Jadwiga , Kaim Andrzej , Pietrasik Krzysztof , Trzciñska Kinga 
Published: April 2010

AbstractThe initial stage of the di‐TEMPO (N,N′‐bis(4‐(2,2,6,6‐tetramethylpiperidin‐1‐yloxyl))diaminobutane) controlled radical polymerization of styrene was investigated by electron spin resonance (ESR) method in a temperature range of 300–410 K. Processes corresponding to three subsequent temperature subranges 300–360, 360–375, and 375–410 K have been discussed. The decrease of concentration of the di‐TEMPO biradicals is faster than for the TEMPO monoradicals in the range 370–390 K. The reduced mobility of capping groups is postulated to be responsible for the differences between TEMPO monoradical and di‐TEMPO biradical mediators. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010