bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: 4,5‐Diaryl‐3‐aminopyrazole Derivatives as Analogues of Combretastatin A‐4: Synthesis and Biological Evaluation.
Authors: Liu Tao , Cui Rong , Chen Jing , Zhang Jun , He Qiaojun , Yang Bo , Hu Yongzhou 
Published: August 2011

AbstractA number of 4,5‐diaryl‐3‐aminopyrazole derivatives (II) and their corresponding N‐acyl derivatives (IV) are synthesized and evaluated for their in vitro cytotoxicity against five human cancer cell lines.
ChemInform Abstract: Unexpected Formation of Pyrazolecarbaldehyde Dithioacetal Hydrochlorides
Authors: Papernaya L. K. , Shatrova A. A. , Albanov A. I. , Rudyakova E. V. , Levkovskaya G. G. 
Published: August 2011

Abstractby acetalization of pyrazole‐4‐carbaldehydes (I) with 2‐sulfanylethanol (II) in the presence of Tms‐Cl
ChemInform Abstract: An Efficient One Pot Synthesis of New Indanopyrazoline and Indanopyrazole Derivatives.
Authors: Jelizi Hanene , Rammah Mohamed M. , Askri Moheddine , Rammah Mohamed El Baker , Ciamala Kabula , Monnier‐Jobe Karin 
Published: August 2011

AbstractNovel fused pyrazolines (III) and pyrazoles (IV) are obtained in a one‐pot process by regio‐ and diastereoselective 1,3‐dipolar cycloaddition of in situ generated nitrilimines to indenes (I).
ChemInform Abstract: Ionic Liquid Supported Multistep Divergent Synthesis of Benzimidazole Linked Pyrrolo‐/pyrido‐/isoindolo‐benzimidazolones.
Authors: Thummanagoti Suman , Yellol Gorakh S. , Sun Chung‐Ming 
Published: August 2011

AbstractThe microwave‐assisted aminoalkylation of phenylenediamines, immobilized with an ionic liquid with ketoacids is followed by 2 intramolecular cyclization steps to provide the title compounds (IV) and (VII) after cleavage of the support.
ChemInform Abstract: Copper Induced Cyclization of α,β‐Unsaturated Carbonyl Compounds to Isoxazoles.
Authors: Browder Cindy C. , Moss Christopher B. , Kraft Matthew B. , Petrucka Paige L. , Morey Tara S. , Leach Christopher W. , Gearhart Nicholas C. 
Published: August 2011

AbstractAn unusual synthesis of isoxazoles from α,β‐unsaturated ketoximes (E/Z mixture) is reported.
ChemInform Abstract: Synthesis and Antiproliferative Activity of Multisubstituted N‐Fused Heterocycles Against the Hep‐G2 Cancer Cell Line.
Authors: Shen Yong‐Miao , Lv Peng‐Cheng , Zhang Ming‐Zhu , Xiao Hui‐Quan , Deng Li‐Ping , Zhu Hai‐Liang , Qi Chen‐Ze 
Published: August 2011

AbstractThe [3 + 2] cycloaddition reactions of imidazolium ylides and thiazolium ylides with alkenes followed by oxidative aromatization of the primary cycloadducts using the mild oxidant tetrakispyridinecobalt(II) dichromate in one‐pot lead to pyrrolo[1,2‐a]imidazole and pyrrolo[2,1‐b]thiazole derivatives, respectively.
ChemInform Abstract: Bifunctional Cinchona Alkaloids‐Catalyzed Asymmetric [4 + 2] Cycloaddition Reaction of β,γ‐Unsaturated α‐Keto Esters with Oxazolones.
Authors: Ying Yin , Chai Zhuo , Wang Hai‐Feng , Li Peng , Zheng Chang‐Wu , Zhao Gang , Cai Yue‐Peng 
Published: August 2011

AbstractAsymmetric [4 + 2] cycloaddition of β,γ‐unsaturated α‐keto esters (I) and (IV) with oxazolones (II) proceeds with excellent diastereoselectivity and high enantioselectivity (up to 97% e.e.) in the presence of a quinidine‐derived bifunctional organocatalyst (NQD).
ChemInform Abstract: Tetrabutylammonium Hydrogen Sulfate Mediated Domino Reaction: Synthesis of Novel Benzopyran‐Annulated Pyrano[2,3‐c]pyrazoles
Authors: Parmar Narsidas J. , Teraiya Shashikant B. , Patel Rikin A. , Talpada Navin P. 
Published: August 2011

Abstractin a highly stereoselective manner
ChemInform Abstract: Flow Microreactor Synthesis of Disubstituted Pyridines from Dibromopyridines via Br/Li Exchange Without Using Cryogenic Conditions.
Authors: Nagaki Aiichiro , Yamada Shigeyuki , Doi Masatomo , Tomida Yutaka , Takabayashi Naofumi , Yoshida Jun‐ichi 
Published: August 2011

AbstractAn efficient method for the synthesis of the title compounds under higher temperatures is presented by using an integrated flow microreactor system composed of four micromixers and 4 microtube reactors.
ChemInform Abstract: Rhodium(III)‐Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies.
Authors: Guimond Nicolas , Gorelsky Serge I. , Fagnou Keith 
Published: August 2011

AbstractA mild redox‐neutral strategy is applied to the synthesis of isoquinolone and 3,4‐dihydroisoquinolones.
ChemInform Abstract: A Base‐Promoted Cyclization of N‐Propargylaminopyridines. Synthesis of Imidazo[1,2‐a]pyridine Derivatives.
Authors: Husinec Suren , Markovic Rade , Petkovic Milos , Nasufovic Veselin , Savic Vladimir 
Published: August 2011

AbstractThe cyclization to the biologically important heterocyclic skeleton is best accomplished using pyridines which bear Boc‐protected N‐propargyl side chains.
ChemInform Abstract: Aerobic Pd‐Catalyzed sp3 C—H Olefination: A Route to Both N‐Heterocyclic Scaffolds and Alkenes.
Authors: Stowers Kara J. , Fortner Kevin C. , Sanford Melanie S. 
Published: August 2011

AbstractThe Pd‐catalyzed olefination and cyclization of various 2‐alkylpyridines and α,β‐unsaturated alkenes utilizes air as the terminal oxidant and provides a conceptually novel entry to 6,5‐nitrogen heterocycles, which constitute the cores of numerous alkaloid natural products.
ChemInform Abstract: Synthesis of 4‐(Aminoalkyl) Substituted 1,3‐Dioxanes as Potent NMDA and σ Receptor Antagonists.
Authors: Utech Tina , Koehler Jens , Wuensch Bernhard 
Published: August 2011

AbstractDiverse 4‐(aminoalkyl) substituted 1,3‐dioxanes (VII) and (X)‐(XII) are tested for their binding affinity to NMDA and σ receptors.
ChemInform Abstract: An Efficient Green Chemical Approach for the Synthesis of Structurally Diverse Spiroheterocycles with Fused Heterosystems.
Authors: Arya Anand Kumar , Kumar Mahendra 
Published: August 2011

AbstractA simple, convenient, environmentally benign, and mild synthetic method for the synthesis of the title compounds (IV), (VI), (VIII), and (X) with a green and recyclable catalyst is presented.
ChemInform Abstract: Quinoxaline Synthesis in Novel Tandem One‐Pot Protocol.
Authors: Kumar B. S. P. Anil , Madhav B. , Reddy K. Harsha Vardhan , Nageswar Y. V. D. 
Published: August 2011

AbstractA broad spectrum of highly substituted, biologically interesting title compounds is prepared in water and absence of any catalyst via bromination of β‐dicarbonyl compounds, followed by condensation of the resulting bromides with phenylenediamines.
ChemInform Abstract: Convergent Asymmetric Disproportionation Reactions: Metal/Broensted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines.
Authors: Chen Qing‐An , Wang Duo‐Sheng , Zhou Yong‐Gui , Duan Ying , Fan Hong‐Jun , Yang Yan , Zhang Zhang 
Published: August 2011

AbstractEmploying hydrogen gas as the reductant makes the self‐transfer disproportionation of in‐situ generated dihydroquinoxalines an ideal atom‐economical process.
ChemInform Abstract: Gold Catalysis: 1,3‐Oxazines by Cyclization of Allene Amides.
Authors: Hashmi A. Stephen K. , Schuster Andreas M. , Litters Sebastian , Rominger Frank , Pernpointner Markus 
Published: August 2011

AbstractIn gold‐catalyzed reactions, allenamides mainly afford 1,3‐oxazines through atypical 6‐exo‐dig or 6‐endo‐dig cyclizations.
ChemInform Abstract: Microwave Assisted Synthesis and Structure—Activity Relationship of 4‐Hydroxy‐N′‐ [1‐phenylethylidene]‐2H/2‐methyl‐1,2‐benzothiazine‐3‐carbohydrazide 1,1‐Dioxides as Antimicrobial Agents.
Authors: Ahmad Naveed , Zia‐ur‐Rehman Muhammad , Siddiqui Hamid Latif , Ullah Muhammad Fasih , Parvez Masood 
Published: August 2011

AbstractMost of the synthesized compounds are found to possess moderate to significant antimicrobial activities.
ChemInform Abstract: N‐Acylaminophenothiazines: Neuroprotective Agents Displaying Multifunctional Activities for a Potential Treatment of Alzheimer′s Disease.
Authors: Rodriguez‐Franco Maria Isabel , et al. et al. 
Published: August 2011

AbstractThe novel title compounds (IV) display interesting pharmacological properties regarding their ability to selectively inhibit butyrylcholinesterase and protect neurons against oxidative stress whilst displaying low toxicity.
ChemInform Abstract: Reaction of 1,3‐Dihalopropan‐2‐ones with 2‐Sulfanylbenzoic Acid Mono‐ and Disodium Salts.
Authors: Tokareva I. A. , Shagun L. G. , Dorofeev I. A. , Shagun V. A. , Voronkov M. G. 
Published: August 2011

AbstractThe title reactions provide access to macrocyclic compound (V) and benzothiocinedione (VII), respectively.
ChemInform Abstract: Stereoselective Synthesis of P‐Stereogenic Aminophosphines: Ring Opening of Bulky Oxazaphospholidines.
Authors: Leon Thierry , Riera Antoni , Verdaguer Xavier 
Published: August 2011

AbstractThe ring opening of oxazaphospholidine—borane complex (I) with Grignard compounds proceeds with inversion of the configuration at the phosphorus center to give (indanylamino)phosphine—borane complexes as single diastereoisomers in most cases.
ChemInform Abstract: Electrophilic Trifluoromethylation of S‐Hydrogen Phosphorothioates.
Authors: Santschi Nico , Togni Antonio 
Published: August 2011

AbstractTreatment of phosphorothioates of type (III) with the iodo compound (IV) allows access to various biologically important S‐trifluoromethylated phosphorothioates.
ChemInform Abstract: Design, Synthesis and Cytotoxicity of a New Series of Isoxazolidine Based Nucleoside Analogues.
Authors: Piotrowska Dorota G. , Cieslak Marcin , Krolewska Karolina , Wroblewski Andrzej E. 
Published: August 2011

AbstractA new approach to the synthesis of 5‐arylisoxazolidine‐3‐phosphonates (III) (10 examples) utilizing 1,3‐dipolar cycloaddition of nitrone (I) to styrenes is accomplished.
ChemInform Abstract: The GAP Chemistry for Chiral N‐Phosphonyl Imine‐Based Strecker Reaction.
Authors: Kaur Parminder , Wever Walter , Pindi Suresh , Milles Raizada , Gu Peng , Shi Min , Li Guigen 
Published: August 2011

AbstractThe presented asymmetric synthesis of the compounds (III) includes the use of a non‐volatile and inexpensive cyanide source with iPrOH as co‐additive.
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Phenylation of N‐Phosphinoylarylimines with Triphenylborane.
Authors: Hao Xinyu , Chen Qian , Kuriyama Masami , Yamada Ken‐ichi , Yamamoto Yasutomo , Tomioka Kiyoshi 
Published: August 2011

AbstractThe proline‐derived catalyst (I) is effective in the title reaction.
ChemInform Abstract: Iron Salt, a Cheap, Highly Efficient and Environment‐Friendly Metal Catalyst for Se—Se Bond Cleavage and Further Reaction with Methylenecyclopropanes under Mild Conditions.
Authors: Yu Lei , Ren Lingfeng , Yi Rong , Wu Yulan , Chen Tian , Guo Rong 
Published: August 2011

AbstractMonosubstituted methylene cyclopropanes react with diphenyl diselenide to afford 1,1‐diphenylselenylcyclobutanes (III) with high yields.
ChemInform Abstract: Enantioconvergent Hydroboration of a Racemic Allene: Enantioselective Synthesis of (E)‐δ‐Stannyl‐anti‐homoallylic Alcohols via Aldehyde Crotylboration.
Authors: Chen Ming , Roush William R. 
Published: August 2011

AbstractThe hydroboration of racemic allenes with (+)‐diisopinocampheylborane converts both allene enantiomers into the same intermediate, which by reaction with aldehydes affords the title alcohols in excellent enantioselectivity.
ChemInform Abstract: Decarboxylation of Aromatic Carboxylic Acids by Gold(I)‐N‐Heterocyclic Carbene (NHC) Complexes.
Authors: Dupuy Stephanie , Lazreg Faima , Slawin Alexandra M. Z. , Cazin Catherine S. J. , Nolan Steven P. 
Published: August 2011

AbstractGold(I)‐aryl complexes (III) are synthesized under mild conditions from a gold(I) hydroxo precursor without the need for silver co‐catalysis.
ChemInform Abstract: Alkoxyamine‐Cyanoborane Adducts: Efficient Cyanoborane Transfer Agents.
Authors: Marquez Jose M. , Martinez‐Castro Elisa , Gabrielli Serena , Lopez Oscar , Maya Ines , Angulo Manuel , Alvarez Eleuterio , Fernandez‐Bolanos Jose G. 
Published: August 2011

AbstractPreviously unknown zwitterionic alkoxyamino cyanoboranes are synthesized and successfully used as novel boron transfer agents towards aliphatic amines including amnosugars [→ (V), (VII)].
ChemInform Abstract: Efficient Acylation and Sulfation of Carbohydrates Using Sulfamic Acid, a Mild, Eco‐Friendly Catalyst under Organic Solvent‐Free Conditions.
Authors: Santra Abhishek , Guchhait Goutam , Misra Anup Kumar 
Published: August 2011

AbstractIn the presence of the title catalyst fast and efficient acylation of carbohydrate derivatives, e.g. (I), and free sugars, cf.
ChemInform Abstract: Benzamides and Quinazolines from a Mangrove Actinomycetes Streptomyces sp. (No. 061316) and Their Inhibiting Caspase‐3 Catalytic Activity in vitro
Authors: Yao Xinsheng , et al. et al. 
Published: August 2011

Abstractisolation, structure and inhibitory effects of one new benzamide (I), two known benzamides and three known quinazolines on Caspase‐3 in vitro
ChemInform Abstract: Synthesis of (.+‐.) Travoprost and Its Analogues.
Authors: Mudduluru Harikrishna , Hindupur Rama M. , Dubey Pramod K. , Madhavaram Shankar , Tatini Lakshmikumar , Subbaraju Gottumukkala V. 
Published: August 2011

AbstractStarting from the known intermediate (I), a new synthetic approach to the prostaglandin analogue and antiglaucoma agent travoprost (VIIb) and its derivatives is developed.
ChemInform Abstract: 3,6,7‐Tri‐epi‐invictolide, a Diastereomer of Queen Recognition Pheromone, and Its Analogue from a Marine‐Derived Actinomycete.
Authors: Sato Seizo , Iwata Fumie , Yamada Shoichi , Kawahara Hiroyuki 
Published: August 2011

AbstractStereochemistry and biosynthetic origin of tri‐epi‐invictolide (Ia) and its analog (Ib) are investigated.
ChemInform Abstract: The First Total Synthesis of Tarennane, a Potent Antioxidant Chalcone Constituent from Tarenna Attenuate or Magnolia Officinalis.
Authors: Yang Jincheng , Yang Tao , Luo Youfu , He Jun , Shi Jianyou , Peng Aihua 
Published: August 2011

AbstractTitle compound (IV), a naturally occurring antioxidant, is synthesized for the first time.
ChemInform Abstract: Supported Transition Metal Catalysts for Hydrodechlorination Reactions
Authors: Keane Mark A. 
Published: August 2011

AbstractReview: overview of existing methods, benefits of catalytic hydrodechlorination (HDC) over separation/oxidation methods, detailed considerations of liquid phase HDC of chlorophenols over Al supported Pd and gas phase conversion of halogenated aromatics over silica supported Ni; 321 refs.
ChemInform Abstract: Supported Noble Metal Nanoparticles as Photo/Sono‐Catalysts for Synthesis of Chemicals and Degradation of Pollutants
Authors: Wen Bo , Ma Jia Hai , Chen Chun Cheng , Ma Wan Hong , Zhu Huai Yong , Zhao Jin Cai 
Published: August 2011

AbstractReview: 55 refs.
Theoretical Study on Cooperativity Effects between Anion–π and Halogen‐Bonding Interactions
Authors: Estarellas Carolina , Frontera Antonio , Quiñonero David , Deyà Pere M. 
Published: August 2011

AbstractThis article analyzes the interplay between lone pair–π (lp–π) or anion–π interactions and halogen‐bonding interactions. Interesting cooperativity effects are observed when lp/anion–π and halogen‐bonding interactions coexist in the same complex, and they are found even in systems in which the distance between the anion and halogen‐bond donor molecule is longer than 9 Å. These effects are studied theoretically in terms of energetic and geometric features of the complexes, which are computed by ab initio methods. Bader′s theory of “atoms in molecules” is used to characterize the interactions and to analyze their strengthening or weakening depending upon the variation of charge density at critical points. The physical nature of the interactions and cooperativity effects are studied by means of molecular interaction potential with polarization partition scheme. By taking advantage of all aforementioned computational methods, the present study examines how these interactions mutually influence each other. Additionally, experimental evidence for such interactions is obtained from the Cambridge Structural Database (CSD).
Design of nonlinear PID control systems using boosting algorithm
Authors: Kawanari Sho , Ohnishi Yoshihiro 
Published: August 2011

AbstractThere are many nonlinear systems among process control systems. However, it is difficult to handle nonlinear properties with a linear controller. Thus, various methods have been studied in this field. On the other hand, a scheme called boosting has been proposed in the machine learning field. This scheme can obtain highly accurate conditions by combining less‐accurate conditions. Boosting can obtain better results than a neural network with fewer learning data. In this paper, we propose a method for the design of nonlinear PID control systems using the boosting algorithm. The original boosting is capable of dealing only with two‐valued variables, and thus we extend the algorithm for function approximation using it. Finally, simulation examples are presented in order to demonstrate the effectiveness of the proposed scheme. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(9): 52–58, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10310
Aminobromination of β‐Nitrostyrene Derivatives with N,N‐Dibromourethane as the Aminobrominating Reagent
Authors: Chen Zhan‐Guo , Zhao Peng‐Fei , Wang Yun 
Published: August 2011

AbstractA concise and efficient aminobromination reaction for β‐nitrostyrene derivatives by treatment with N,N‐dibromourethane was developed. For the β‐nitrostyrene derivatives, the aminobromination successfully proceeded at room temperature in CH3CN without catalysis or protection by an inert gas and gave products in excellent yields (80–97 %). For the β‐methyl analogs, the reaction proceeded smoothly with anhydrous K2CO3 as a catalyst under the same conditions to provide the aminobrominated products in good yields (53–78 %). A possible pathway for this electrophilic addition reaction is proposed.
Highly Enantioselective Michael Addition of 3‐Aryloxindoles to Phenyl Vinyl Sulfone Catalyzed by Cinchona Alkaloid‐Derived Bifunctional Amine–Thiourea Catalysts Bearing Sulfonamide as Multiple Hydrogen‐Bonding Donors
Authors: Zhao Mei‐Xin , Tang Wen‐Hao , Chen Ming‐Xiao , Wei Deng‐Ke , Dai Tong‐Lei , Shi Min 
Published: August 2011

AbstractA highly enantioselective Michael addition of 3‐aryloxindole to phenyl vinyl sulfone catalyzed by a quinine‐derived bifunctional amine–thiourea‐bearing sulfonamide as multiple hydrogen‐bonding donor catalyst has been investigated. The corresponding adducts, which contain a chiral quaternary carbon center at the 3‐position of the oxindole, were obtained in moderate‐to‐good yields (52–86 %) with high‐to‐excellent enantioselectivities (83–98 % ee).
Synthesis of Pyrido[1,2‐a]benzimidazoles through a Copper‐Catalyzed Cascade C–N Coupling Process
Authors: Wu Zhiqing , Huang Qing , Zhou Xiangge , Yu Lintao , Li Zhengkai , Wu Di 
Published: August 2011

AbstractA simple and efficient method for the preparation ofpyrido[1,2‐a]benzimidazoles by a copper‐catalyzed inter‐ and intramolecular C–N coupling cascade process was designed and carried out, and the products were obtained in moderate to excellent yields (up to 93 %).
The Water Uptake of Plasticized Poly(vinyl chloride) Solid‐Contact Calcium‐Selective Electrodes
Authors: Lindfors Tom , Sundfors Fredrik , Höfler Lajos , Gyurcsányi Róbert E. 
Published: August 2011

AbstractA hyphenated method based on FTIR‐ATR and electrochemical impedance spectroscopy has been applied to simultaneously measure the water uptake, changes in the bulk resistance and potential of plasticized poly(vinyl chloride) (PVC) based Ca2+‐selective coated‐wire (CaCWE) and solid‐contact electrodes (CaSCISEs). Most of the water uptake of the ion‐selective membranes (ISMs) used in both electrode types took place within the first 9 h in 10−3 M CaCl2 showing good correlation with the stabilization of the individual electrode potentials. The bulk resistance of the ISMs of the CaCWEs and the CaSCISEs with poly(3‐octylthiophene) (POT) as the solid‐contact (SC) increased most during the first 18 h in 10−3 M CaCl2. The increase in the resistance was found to be related to the exchange of K+ for Ca2+ in the ISM and the formation of the Ca2+‐ionophore (ETH 5234) complex having a lower diffusivity than the free K+ ions. In contrary to previously published results on silicone rubber based SCISEs and poly(methyl methacrylate):poly(n‐decyl methacrylate) membranes containing POT, the plasticized PVC‐based CaSCISEs with POT as the SC had a higher water uptake than the CaCWEs. The CaSCISEs had a detection limit of 2×10−8 M Ca2+ and a good potential reproducibility of 148.9±1.0 mV in 10−4 M CaCl2.
Comparative study on effect of mixed photosensitizer system for solar energy conversion and storage: Brilliant cresyl blue + toluidine blue–ethylene glycol–NaLS system
Authors: Gangotri K.M. , Kumar Mahawar Amit 
Published: August 2011

AbstractThe efforts have been made to enhance the electrical output, conversion efficiency, and storage capacity of the photogalvanic cell in this research work. It has also been emphasized to reduce the cost of construction of the cell by using cheaper, stable, and very dilute solutions in the photogalvanic cell so developed. A mixture of two photosensitizers (Brilliant cresyl blue + Toluidine blue), ethylene glycol as reductant and sodium lauryl sulphate as surfactant, have been used in photogalvanic cell. The observed values of electrical output‐photopotential, photocurrent, and power of the photogalvanic cell are 871.0 mV, 630.0 μA, and 548.73 μW, respectively. The mixed photosensitizer system can work for 70.0 min in dark to use whenever needed. The observed conversion efficiency of the photogalvanic cell is 1.87%. The effect of various parameters on electrical output has also been studied along with i‐V Characteristics of the photogalvanic cell. A mechanism for the photogeneration of electricity is also proposed. © 2011 American Institute of Chemical Engineers, 2011
An inventory of the energy use and carbon dioxide emissions from island tourism based on a life cycle assessment approach
Authors: Kuo Nae‐Wen , Lin Chia‐Yun , Chen Pei‐Hun , Chen Yung‐wei 
Published: August 2011

AbstractTourism is an economic activity that results in a wide range of environmental impacts. The contribution of tourism to human‐induced climate change is an increasingly important issue. However, the energy use and greenhouse gas emissions from tourism products have never been thoroughly discussed. This study uses life cycle assessment (LCA) to explore energy use and CO2 emissions of island tourism and then compare the environmental loads of different tourism subsectors.This study uses three Taiwanese islands (Penghu, Kinmen, and Green islands) as examples to examine the LCA approach, and it calculates and compares the energy usage and CO2 emissions of the transportation, accommodation, and recreation activity sectors. Results show that each tourist consumes 502, 447, and 118 MJ of energy per day on Penghu, Kinmen, and Green islands, respectively. Each tourist also generates 34.0, 27.9, and 7.1 kg of CO2 emissions on Penghu, Kinmen, and Green islands, respectively. Each Penghu tourist per day consumes 4.25 times as much energy as each Green tourist, and each Penghu tourist generates 4.7 times the CO2 emissions as each Green tourist. In summary, the transportation sector generates the largest energy (49–67%) and the largest proportion of CO2 emissions (58–72.4%); the airplane sector is the primary contributor. Finally, this study discuses the advantages and limitations of the LCA approach. © 2011 American Institute of Chemical Engineers Environ Prog, 2011