bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive analysis of the endothelin system in the kidneys of mice, rats, and humans
Authors: Patel Margi , Harris Nicholas , Kasztan Malgorzata , Hyndman Kelly A. 
Published: June 2024

Abstract
The intrarenal endothelin (ET) system is an established moderator of kidney physiology and mechanistic contributor to the pathophysiology and progression of chronic kidney disease in humans and rodents. The aim of the present study was to characterize ET system by combining single cell RNA sequencing (scRNA-seq) data with immunolocalization in human and rodent kidneys of both sexes. Using publicly available scRNA-seq data, we assessed sex and kidney disease status (human), age and sex (rats), and diurnal expression (mice) on the kidney ET system expression. In normal human biopsies of both sexes and in rodent kidney samples, the endothelin-converting enzyme-1 (ECE1) and ET-1 were prominent in the glomeruli and endothelium. These data agreed with the scRNA-seq data from these three species, with ECE1/Ece1 mRNA enriched in the endothelium. However, the EDN1/Edn1 gene (encodes ET-1) was rarely detected, even though it was immunolocalized within the kidneys, and plasma and urinary ET-1 excretion are easily measured. Within each species, there were some sex-specific differences. For example, in kidney biopsies from living donors, men had a greater glomerular endothelial cell endothelin receptor B (Ednrb) compared with women. In mice, females had greater kidney endothelial cell Ednrb than male mice. As commercially available antibodies did not work in all species, and RNA expression did not always correlate with protein levels, multiple approaches should be considered to maintain required rigor and reproducibility of the pre- and clinical studies evaluating the intrarenal ET system.
Molecular regulators of defective placental and cardiovascular development in fetal growth restriction
Authors: Umapathy Anandita , Clark Alys , Sehgal Arvind , Karanam Vijaya , Rajaraman Gayathri , Kalionis Bill , Jones Helen N. , James Jo , Murthi Padma 
Published: June 2024

Abstract
Placental insufficiency is one of the major causes of fetal growth restriction (FGR), a significant pregnancy disorder in which the fetus fails to achieve its full growth potential in utero. As well as the acute consequences of being born too small, affected offspring are at increased risk of cardiovascular disease, diabetes and other chronic diseases in later life. The placenta and heart develop concurrently, therefore placental maldevelopment and function in FGR may have profound effect on the growth and differentiation of many organ systems, including the heart. Hence, understanding the key molecular players that are synergistically linked in the development of the placenta and heart is critical. This review highlights the key growth factors, angiogenic molecules and transcription factors that are common causes of defective placental and cardiovascular development.
Experimental validation of magnetic control strategy in LCC‐S compensated wireless power transfer systems
Authors: Solimene Luigi , Corti Fabio , Musumeci Salvatore , López‐Alcolea Francisco Javier , Reatti Alberto , Ragusa Carlo Stefano 
Published: June 2024

AbstractThe paper explores the use of the magnetic control strategy for the output power regulation of an LCC‐S compensated inductive wireless power transfer system. The magnetic control is implemented through a controlled variable inductor whose magnetization state is actively regulated by an auxiliary DC–DC converter. The principles for the design and regulation of the system are discussed, and the experimental setup for the validation of the regulation method is implemented. Several measurement results highlight the effectiveness and potential improvements of the magnetic control strategy for inductive wireless power transfer systems.
Backward–forward sweep inverse power flow for distribution line parameters estimation with metering data
Authors: Leal Pedro C. , Carvalho Pedro M. S. 
Published: June 2024

AbstractThe transition towards the smart grid requires better information on the electrical networks at the distribution system level. Information about electrical line parameters is a critical part of such information. An algorithm for estimating electric line parameters of medium‐voltage distribution networks is proposed. The algorithm relies upon active/reactive power and nodal voltage magnitude data from advanced metering infrastructure and combines an Ordinary Least Squares estimator with the classical Backward–Forward Sweep load‐flow method to iteratively estimate the admittance parameters of the electrical network components. The algorithm is proposed to be applied to balanced loading situations of networks where zero‐injection non‐monitored nodes may exist. Simulations using the IEEE 33‐bus system are used to demonstrate the effectiveness of the method under different loading situations and measurement noise levels.
ALMA reveals a dust-obscured galaxy merger at cosmic noon
Authors: Langan I. , Popping G. , Ginolfi M. , Gentile F. , Valentino F. , Kaasinen M. 
Published: June 2024

Context. Galaxy mergers play a critical role in galaxy evolution. They alter the size, morphology, dynamics, and composition of galaxies. Galaxy mergers have so far mostly been identified through visual inspection of their rest-frame optical and near-IR (NIR) emission. Dust can obscure this emission, however, resulting in the misclassification of mergers as single galaxies and in an incorrect interpretation of their baryonic properties.
Aims. Having serendipitously discovered a dust-obscured galaxy merger at z = 1.17, we aim to determine the baryonic properties of the two merging galaxies, including the star formation rate (SFR) and the stellar, molecular gas and dust masses.
Methods. Using Band 3 and 6 observations from the Atacama Large Millimeter and submillimeter Array (ALMA) and ancillary data, we studied the morphology of this previously misclassified merger. We deblended the emission, derived the gas masses from CO observations, and modeled the spectral energy distributions to determine the properties of each galaxy. Using the rare combination of ALMA CO(2–1), CO(5–4) and dust-continuum (rest-frame 520 μm) observations, we provide insight into the gas and dust content and into the properties of the interstellar medium of each merger component.
Results. We find that only one of the two galaxies is highly obscured by dust, but both are massive (> 1010.5 M⊙) and highly star forming (SFR = 60 − 900 M⊙/yr), have a moderate-to-short depletion time (tdepl < 0.7 Gyr) and a high gas fraction (fgas ≥ 1).
Conclusions. These properties can be interpreted as the positive impact of the merger. With this serendipitous discovery, we highlight the power of (sub)millimeter observations to identify and characterise the individual components of obscured galaxy mergers.
X-raying the ζ Tau binary system
Authors: Nazé Yaël , Motch Christian , Rauw Gregor , Smith Myron A. , Robrade Jan 
Published: June 2024

Context. The Be star ζ Tau was recently reported to be a γ Cas analog; that is, it displays an atypical (bright and hard) X-ray emission. The origin of these X-rays remains debated.
Aims. The first X-ray observations indicated a very large absorption of the hot plasma component (NH ~ 1023 cm−2). This is most probably related to the edge-on configuration of the ζ Tau disk. If the X-ray emission arises close to the companion, an orbital modulation of the absorption could be detected as the disk comes in and out of the line of sight.
Methods. New XMM-Newton data were obtained to characterize the high-energy properties of ζ Tau in more detail. They are complemented by previous Chandra and SRG/eROSITA observations as well as by optical spectroscopy and TESS photometry.
Results. The high-quality XMM-Newton data reveal the presence of a faint soft X-ray emission, which appears in line with that recorded for non-γ Cas Be stars. In addition, ζ Tau exhibits significant short-term variability at all energies, with larger amplitudes at lower frequencies (“red noise”), as is found in X-ray data of other γ Cas stars. Transient variability (softness dip, low-frequency signal) may also be detected at some epochs. In addition, between X-ray exposures, large variations in the spectra are detected in the 1.5–4 keV energy band. They are due to large changes in absorption toward the hottest (9 keV) plasma. These changes are not correlated with either the orbital phase or the depth of the shell absorption of the Hα line. These observed properties are examined in the light of proposed γ Cas models.
COLDSIM predictions of [C II] emission in primordial galaxies
Authors: Casavecchia Benedetta , Maio Umberto , Péroux Céline , Ciardi Benedetta 
Published: June 2024

Context. A powerful tool with which to probe the gas content at high redshift is the [C II] 158 μm submillimetre emission line, which, due to its low excitation potential and luminous emission, is considered a possible direct tracer of star forming gas.
Aims. In this work, we investigate the origin, evolution, and environmental dependencies of the [C II] 158 μm emission line, as well as its expected correlation with the stellar mass and star formation activity of the high-redshift galaxies observed by JWST.
Methods. We use a set of state-of-the-art cold-gas hydrodynamic simulations (COLDSIM) with fully coupled time-dependent atomic and molecular non-equilibrium chemistry and self-consistent [C II] emission from metal-enriched gas. We accurately track the evolution of H I, H II, and H2 in a cosmological context and predict both global and galaxy-based [C II] properties.
Results. For the first time, we predict the cosmic mass density evolution of [C II] and find that it is in good agreement with new measurements at redshift z = 6 from high-resolution optical quasar spectroscopy. We find a correlation between [C II] luminosity, L[C II], and stellar mass, which is consistent with results from ALMA high-redshift large programs. We predict a redshift evolution in the relation between L[C II] and the star formation rate (SFR), and provide a fit to relate L[C II] to SFR, which can be adopted as a more accurate alternative to the currently used linear relation.
Conclusions. Our findings provide physical grounds on which to interpret high-redshift detections in contemporary and future observations, such as the ones performed by ALMA and JWST, and to advance our knowledge of structure formation at early times.
Pediatric dermatological vital emergencies
Authors: Chiriac Anca , Diaconeasa Adriana , Miulescu Raluca , Voicu Cristiana , Chiriac Anca E. , Fölster-Holst Regina , Wollina Uwe 
Published: June 2024

AbstractPediatric patients in the emergency unit often present with muco-cutaneous symptoms. Most
muco-cutaneous findings are not life-threatening, but it is crucial to identify those
dermatoses with urgent need of treatment. In this review, we present infectious and
non-infectious pediatric disorders with muco-cutaneous red-flag signs for a potential severe
course and complications associated with significant mortality. By recognizing these
dermatological symptoms, early confirmation of diagnosis and initiation of appropriate
treatment outcome can be optimized.
A Rare Presentation of Functional Movement Disorder Mimicking Normal Pressure Hydrocephalus
Authors: Onder Halil , Ulker Aycan Cemil , Comoglu Selcuk 
Published: June 2024

AbstractHerein, we describe a 55-year-old female patient with a functional movement disorder (FMD) who presented with normal pressure hydrocephalus (NPH)-like clinic. The neuroimaging data and positive response to the tap test initially suggested NPH. However, a detailed investigation of the clinic features yielded a final diagnosis of FMD. Via the presentation of this patient, we expand the phenomenology of FMD. To our knowledge, this is the first presentation of a patient with FMD mimicking NPH. Therefore, we think this rare illustration is interesting and may provide valuable perspectives for clinical practice.
A Long-Term Follow-up Study of Asthmatic Children Discontinued Allergen-Specific Immunotherapy
Authors: Huang Yana , Huang Ying , Li Jie , Zhang Benjin 
Published: June 2024

AbstractOur objective was to explore the factors associated with the prognosis of allergic asthmatic children with poor compliance with subcutaneous immunotherapy (SCIT). A telephonic follow-up was conducted in 616 asthmatic children who received SCIT treatment from June 2005 to October 2010. The status of asthmatic controlled was based on their level of asthma symptom control when they were followed-up. Seven factors, including sex, age, family history of allergic disease, severity of mite allergy, times of SCIT, whether inhaled corticosteroids regularly, and with rhinitis or not, were analyzed. In total, 322 asthmatic children discontinued the 3-year course of SCIT. Of the 127 children included in the final analysis, 85 (66.9%) were asthmatic controlled patients and 42 (33.1%) were asthmatic uncontrolled patients. The median (interquartile range) age of the 127 asthmatic children was 7.1 ± 4.8 years. The proportion of male and female was 87/40. In the seven factors, family history of allergic diseases (p = 0.035), whether inhaling corticosteroids regularly (p = 0.007), were significantly related to the level of asthma symptom control, whereas the age of these asthmatic children, severity of mite allergy, times of SCIT, and asthma with rhinitis or not had no relation to the level of asthma symptom control. Our findings revealed that the family history of allergic diseases was an important factor affecting the prognosis of childhood asthma, and inhaling corticosteroids regularly after discontinuing SCIT could significantly improve their prognosis. These results could provide value in clinical asthma treatment.
Explaining the German lobbying register law and its reform: combining insights from the Multiple Streams Framework and Punctuated Equilibrium Theory
Authors: Schiffers Maximilian , Plümer Sandra 
Published: June 2024

AbstractThis paper explains the adoption and reform of the German lobbying register law in 2021 and 2023 as a major policy change in German lobbying regulation. Using the Multiple Streams Framework and Punctuated Equilibrium Theory as theoretical lenses, we conduct a congruence analysis of 87 policy documents in a time period from 2017 to 2023. Empirical results show that the lobbying register law represents a quick solution to a different problem (a conflict of interest scandal) and explain the time it took the reform to re-emerge on the policy agenda due to shifted legislative priorities. In line with previous studies on lobbying regulation, we find that scandals need to be combined with other explanatory factors in order to elucidate the introduction and strengthening of transparency measures. These factors are on the micro-level and focus on how political action is channeled by key actors that make use of these scandals to increase pressure to act and generate further attention. With regard to our theoretical lenses, our analysis illustrates that both theories are needed to fully investigate the policy processes.
Testing the simple model of environmental citizenship in a sample of adolescents
Authors: Poškus Mykolas Simas 
Published: June 2024

AbstractEnvironmental citizenship and education for environmental citizenship have been identified as important areas to address, yet there is no simple way of studying either environmental citizenship or how effective is the education for it. In order to address this gap in the literature and to provide a practical model for future studies of environmental citizenship, especially in educational contexts, a Simple Model of Environmental Citizenship (SMEC), consisting of environmental (self-)education, abstract and concrete environmental knowledge, environmental awareness, pro-environmental attitudes, need for learning about environmental issues, need for environmental action, environmental literacy, and environmental citizenship was tested in a sample of adolescents. The objective of the study is to test the SMEC in a sample of adolescents in order to investigate its structure and functioning. The current sample consists of 236 adolescents from two schools in Lithuania recruited through convenience sampling. Structural equation modelling with DWLS estimation was used to test the SMEC. The SMEC, after small adjustments that are consistent with previous research, fit the data well. The SMEC provides a good starting point for future interventional and longitudinal studies with adolescents as well as other age groups.
Direct multiple monochromatic x-ray imaging with a pinhole array and a laterally graded multilayer mirror
Authors: Xu Hao , Wen Shengyou , Si Haoxuan , Huang Qiushi , Zhang Zhe , Zhang Feng , Yi Shengzhen , Wang Zhanshan 
Published: June 2024

Multiple monochromatic x-ray imaging (MMI) is a technique for diagnosing the emission spectra of tracer elements in laser-driven inertial confinement fusion experiments. This study proposes an MMI method that combines a simple pinhole array with a laterally graded multilayer mirror. The method directly obtains multiple monochromatic x-ray images by regulating the multilayer thickness in different mirror positions to compensate for the energy-broadening effect. This paper presents a comprehensive design scheme, the multilayer fabrication and experimental verification of the gradient MMI imaging performance. The experimental results show that the method achieves monochromatic imaging with a spectral resolution of ∼70–90 eV in several keV energy regions. This paper presents a practical diagnostic approach for directly and synchronously capturing the spatial, temporal, and spectral information of laser plasma x rays.
A polarizable valence electron density based force field for high-energy interactions between atoms and molecules
Authors: Romero José , Limão-Vieira Paulo , Maihom Thana , Hermansson Kersti , Probst Michael 
Published: June 2024

High-accuracy molecular force field models suited for hot gases and plasmas are not as abundant as those geared toward ambient pressure and temperature conditions. Here, we present an improved version of our previous electron-density based force field model that can now account for polarization effects by adjusting the atomic valence electron contributions to match ab initio calculated Mulliken partial charges. Using a slightly modified version of the Hohenberg–Kohn theorem, we also include an improved theoretical formulation of our model when applied to systems with degenerate ground states. We present two variants of our polarizable model, fitted from ab initio reference data calculated at CCSD(T)/cc-pVTZ and CCSD(T)/CEP-31G levels of theory, that both accurately model water dimer interaction energies. Further improvements include the additional interaction components with fictitious non-spherically symmetric, yet atom-centered, electron densities and fitting the exchange and correlation coefficients against analytical expressions. The latter removes all unphysical oscillations that are observed in the previous non-polarizable variant of our force field.
Experto crede
Authors: Szczyrbak Magdalena 
Published: June 2024

Abstract
The article explains the processes involved in knowledge sharing and support giving in an open FB forum dedicated
to endometriosis. It builds on the existing understanding of experiential knowledge, as well as adopts Jovchelovitch’s (2007) perspective on knowledge diversity and representation which views knowledge
construction as an intersubjective process. The analysis looks at the what, the who, and the how of the community in question,
focusing in particular on three areas: identity work (self- and other-categorisation); perspective sharing and recognition by
“significant others”; and epistemic self-other positioning. The analysis determines the most common strategies of categorisation,
identifies ways of constructing shared understanding, as well as reveals that the participants’ personal truths are based
primarily on their embodied experience and hearsay.
No seas buey, cabrón
Authors: Maldonado Ricardo 
Published: June 2024

Resumen
El presente artículo analiza la evolución diacrónica de dos vocablos de tratamiento familiar de notable frecuencia
en el español de México cuyo origen designa animales. Su primera extensión semántica durante el siglo XIX es altamente ofensiva
buey = “tonto”, cabrón = “rufián”. Este estudio ubica la emergencia de los valores pragmáticos de ambas formas alrededor de 1960 y
reconoce su uso como representante de importantes cambios de orden social. Con base en la comparación de tres corpus orales de
distintos grados de informalidad, el estudio rastrea la pérdida de rasgos fonémicos y semánticos de cada forma en favor de la
emergencia de valores pragmáticos. Los procesos de erosión fonémica [buey] > [guéi] > [wei] > [we] // [kabrón] >
[kabrón] > [kaón] son interpretados como reflejos de erosión semántica que llevan a la formación de formas de
tratamiento cercano y que, a su vez, desarrollan valores de marcación discursiva siguiendo los pasos de un recurrente proceso de
pragmaticalización.
Selling a Ferrari like Sliced Meat: Confident Stance-Taking, Blockchain Doxa, and the Splitting Power of Asset Tokenization
Authors: Yokoyama Yura 
Published: June 2024

AbstractAsset tokenization, a financial practice that generates tokens based on distributed ledger technologies such as blockchain, is a representational practice in which token issuers establish artificially devised sign relationships between tokens and assets, despite some issues and complexities of blockchain. Human confidence in this practice is critical for its successful implementation. This article suggests that human confidence in blockchain is supported and circulated by the doxa of blockchain, which the article frames as a linguistic phenomenon where people talk more about how to use a given object than about the object itself. By paying attention to the artificially devised sign relations between tokens and assets and confident stance-taking toward blockchain by users, the article argues that a linguistic approach is necessary to understand how human confidence makes asset tokenization happen.
Highlighting and Hiding: Images of Farmers in Chinese News Cartoons
Authors: Xi Rui 
Published: June 2024

AbstractDrawing upon a multimodal corpus consisting of 48 farmer-themed cartoons retrieved from the China News Cartoon Network, this research aims to undertake a comprehensive analysis of farmers’ images constructed through the utilization of various multimodal metaphors and metonymies in news cartoons. A multimodal critical metaphor/metonymy analysis approach will be adopted to lay bare the hidden evaluative attitudes that underlie these tropes. Thorough scrutiny, incorporating both quantitative and qualitative methodologies, the study reveals the existence of five primary stereotypical media images of farmers in the Chinese news media. These include the depiction of farmers as economically disadvantaged laborers, powerless takers reliant on protection, contrasting figures to urban citizens, poorly educated criminals, and beneficiaries of agricultural policies. The predominantly one-dimensional, weakened, and biased images are intentionally (or unintentionally) crafted by the media through the use of metaphorical and metonymic mappings, which involve highlighting certain aspects while concealing others. The negative attitudes, discrimination, and stigmatization toward the least powerful members of Chinese society unveil the underlying unequal power dynamics, social hierarchy, and economic duality.