bluuebunny/crossref_metadata_2025_split huggingface dataset:
Return from exile: Mythology and heritage in American Born Chinese and its Disney adaptation
Authors: Fagan Joshua 
Published: June 2024

AbstractThough American Born Chinese has received a significant degree of scholarly study, the prevalence of cultural exile in the text has not received sufficient attention. Said's theorization on exile provides a guide to examining the mindset of Jin, who willfully accepts exile from his Chinese‐American heritage because of how he feels neither truly Chinese nor truly American. Only through a visceral encounter with Chinese mythology does he return from exile and embrace that heritage. The Disney adaptation, though significant from a “representation” standpoint, removes that threat of exile, diluting the narrative into a reassuring, palatable formula.
Incompatible insect technique: insights on potential outcomes of releasing contaminant females: a proof of concept under semi‐field conditions
Authors: Lombardi Giulia , Lampazzi Elena , Calvitti Maurizio 
Published: June 2024

AbstractBACKGROUNDReleasing large numbers of Aedes albopictus males, carrying the artificially introduced Wolbachia ‘wPip’ strain, results in a decrease in the reproductive capacity of wild females due to a phenomenon known as cytoplasmic incompatibility (CI). This vector control strategy is referred to as the incompatible insect technique (IIT). However, its widespread implementation faces various challenges, including the complexity of removing fertile females from the males intended for release. Here, we present the results of semi‐field experiments comparing the impact of minimal female co‐release on two IIT modes: unidirectional CI‐based (UnCI IIT) and bidirectional CI‐based (BiCI IIT), specifically targeting Ae. albopictus.RESULTSThe contamination of ‘wPip’ infected females (2%) during male releases significantly weakened the overall effectiveness of IIT, emphasizing the need for thorough sex separation. Specifically, with UnCI IIT, despite the low rate of co‐released females, there was a gradual rise in ‘wPip’ infection frequency, resulting in more compatible mating and subsequently higher rates of egg hatching. Conversely, this pattern was effectively mitigated in BiCI IIT owing to the reciprocal sterility between the wild‐type and the ‘wPip’ infected populations.CONCLUSIONThrough an experimental approach, conducted in a semi‐field setting, we have contributed to advancing scientific understanding regarding the potential outcomes of implementing the IIT strategy in the absence of a complete sexing system. The results suggest that safety measures for mitigating the potential impacts of co‐released females can be tailored according to the specific type of IIT being utilized. © 2024 Society of Chemical Industry.
Joint Exfoliation of MXene by Dimensional Mismatched SiC/ZIF‐67 Toward Multifunctional Flame Retardant Thermoplastic Polyurethane
Authors: Bi Xue , Song Kunpeng , Zhang Zeqi , Lin Tao , Pan Ye‐Tang , Fu Wangyang , Song Pingan , He Jiyu , Yang Rongjie 
Published: June 2024

AbstractThe single‐layer MXene fully demonstrates the advantages of 2D materials, especially catalytic, conductive, and mechanical properties. However, the high energy consumption and low efficiency faced by MXene in the divestiture process are still challenges that need to be solved urgently. In this article, dimension mismatch and collaborative stripping strategies are skillfully combined to easily realize the transformation from multi‐layer MXene to single layer. In addition, the functionalized MXene@SiC@polyaniline (MXene@SiC@PANI) nano‐hybrid materials are used as fillers to improve the thermal conductivity, flame retardant, and antibacterial properties of thermoplastic polyurethane (TPU). The surface temperature of TPU/MXene@SiC@PANI composites increased from 33.4 °C to 59.8 °C within 10 s. In addition, the antibacterial efficiency of TPU composites against Escherichia coli and Staphylococcus aureus is 69.6% and 88.9%, respectively. Compared with pure TPU, the peak heat release rate and total heat release are reduced by 71.4% and 34.6%, respectively. The flame‐retardant mechanism of MXene hybrid materials is systematically discussed. It is worth noting that the introduction of PANI enhances the compatibility between the filler and the polymer, effectively maintaining the mechanical properties of the TPU itself. This work provides a convenient method for the multi‐functional practical application of TPU.
Machine learning and nonlinear finite element analysis of fiber‐reinforced polymer‐confined concrete‐steel double‐skin tubular columns under axial compression
Authors: Isleem Haytham F. , Qiong Tang , Chukka Naga Dheeraj Kumar Reddy , Kumar Rakesh , Nagaraju T. Vamsi , Hamed Asmaa Y. 
Published: June 2024

AbstractFiber‐reinforced polymer (FRP)‐confined double‐skin tubular columns (DSTCs) are an innovative type of hybrid columns that consist of an outer tube made of FRP, an inner circular steel tube, and a concrete core sandwiched between them. Available literature focuses on hollow DSTCs with limited research on DSTCs made with inner steel tubes filled with concrete. Overall, DSTCs have many applications, highlighting the importance of studying the effects of concrete filling and strength on the composite system. To address this gap, finite element models (FEMs) and both traditional and innovative machine learning (ML) techniques were used to develop accurate models for predicting load‐bearing capacity and confined ultimate strain under axial loads. A comprehensive database of 60 experimental tests and 45 FEMs simulations of columns was analyzed, with five parameters selected as input variables for ML‐based models. New techniques like gradient boosting (GB), random forest (RF), convolutional neural networks, and long short‐term memory are compared with established algorithms like multiple linear regression, support vector regression (SVR), and empirical mode decomposition (EMD)‐SVR. Regression error characteristics curve, Shapley Additive Explanation analysis, and statistical metrics are used to assess the performance of these models using a database containing 105 FEMs test results that cover a range of input variables. While EMD‐SVR and GB perform well for confined ultimate strain, the suggested EMD‐SVR, GB, and RF models show superior predictive accuracy for confined ultimate load. To be more precise, for confined ultimate load prediction, EMD‐SVR, GB, and RF obtain values of 0.99, 0.989, and 0.960, respectively. The values for GB and EMD‐SVR at confined ultimate strain are 0.690 and 0.99, respectively. However, design engineers are limited by the “black‐box” nature of ML. In order to solve this, the study presents an open‐source GUI based on GB, which gives engineers the ability to precisely estimate confined ultimate load and strain under various test conditions, enabling them to make well‐informed decisions about mix proportion.
SKA Headquarters: Another Two-Stage Site Selection Tussle
Authors: Schilizzi Richard T. , Ekers Ronald D. , Dewdney Peter E. , Crosby Philip 
Published: June 2024

AbstractThe International SKA Project Office (ISPO) was established in 2003 and hosted by ASTRON at its headquarters in Dwingeloo, The Netherlands, the home institute of the SKA Director at that time. As the global component of the project began to expand and substantial funding for coordination of this expansion (through PrepSKA and other initiatives) came into view in 2006–7, the International SKA Steering Committee (ISSC) held a competition in 2007 for the location of the central office. This led to the ISPO, which was renamed the SKA Program Development Office (SPDO), moving to the University of Manchester, initially for the period 2008 to 2011. Another competition was held in 2011 as the prospect of establishing a legal entity to manage the Pre-Construction Phase starting in 2012 emerged. Manchester was selected again. In this chapter we describe these two, at times contentious, selection rounds and the issues involved.
Introduction to Dignity, Freedom and Justice
Authors: Gotoh Reiko , Richardson Henry 
Published: June 2024

AbstractMore than 50 years have passed since the publication of John Rawls's A Theory of Justice (1971) and Amartya Sen's Collective Choice and Social Welfare (1970). This chapter introduces the following three purposes of this book. First, this book seeks to obtain clues for the critical development of the theory of justice and the welfare state by capturing the overlaps and differences between Rawls's political philosophy and Sen's normative economics. Second, this book examines the concept of dignity, which has not received much attention in liberalism. Neither a free competitive market system nor a wage-income redistribution system will be sufficient to protect and respect “dignity”. To protect and respect values stocked and sustained within an individual, it is necessary to pay attention to his/her capability for dignity and capability for utilizing the right to liberties. Third, this book cross-pollinates the methods of liberal social sciences and philosophy, working from existing connections between these two areas. Throughout this book, the reader will find that theories of liberal social science and philosophy contain clues of ideas and methods that critically develop themselves.
A head with two tales: demystifying early spread of disease from the pancreatic head
Authors: Aribindi Swetha , Oliphant Michael , Ponnatapura Janardhana 
Published: June 2024

AbstractThe pancreas is a centrally located extraperitoneal organ within the anterior pararenal space. It is extensively connected to the extraperitoneal spaces by location and a network of mesenteries and ligaments. This provides interconnected avenues for vessels, lymphatics, and nerves to course through—as well as avenues for the spread of disease. The head of the pancreas results from the fusion of its ventral analog (anterior head) with its dorsal analog (posterior head). This differentiation provides two distinct pathways of spread of disease from the head of the pancreas. This communication will discuss the embryology, anatomy, and pathways of disease spread from the anterior and posterior pancreatic head. While any disease process can use these pathways, proven cases of adenocarcinoma of the pancreas are used for illustrations.
The ownership memory self-reference effect shifts recognition criterion but not recognition sensitivity
Authors: Sparks S. D. , Kritikos A. 
Published: June 2024

AbstractInformation referenced to the self is retrieved more accurately than information referenced to others, known as the memory self-reference effect. It is unclear, however, whether social context (identity of the other) or task factors alter decision-making processes. In a virtual object allocation task, female participants sorted objects into their own or another’s (stranger or mother) basket based on a colour cue. Subsequently, they performed a recognition memory task in which they first indicated whether each object was old or new, and then whether it had been allocated to themselves or to the other. We obtained owner-specific hit rates and false-alarm rates and applied signal detection theory to derive separate recognition sensitivity (d’) and recognition criterion parameters (c) for self- and other-owned objects. While there was no clear evidence of a recognition self-reference effect, or a change in sensitivity, participants adopted a more conservative recognition criterion for self- compared with other-owned objects, and particularly when the other-referent was the participant’s mother compared with the stranger. Moreover, when discriminating whether the originally presented objects were self- or other-owned, participants were biased toward ascribing ownership to the ‘other’. We speculate that these findings reflect ownership-based changes in decisional processing during the recognition memory self-reference paradigm.
Real-world use patterns, effectiveness, and tolerability of sacituzumab govitecan for second-line and later-line treatment of metastatic triple-negative breast cancer in the United States
Authors: Kalinsky Kevin , Spring Laura , Yam Clinton , Bhave Manali Ajay , Ntalla Ioanna , Lai Catherine , Sjekloca Nikoleta , Stwalley Brian , Stokes Michael , Taylor Aliki , Nanda Rita 
Published: June 2024

Abstract
Purpose
Patients with metastatic triple-negative breast cancer (mTNBC) have poor prognosis and limited treatment options. Sacituzumab govitecan (SG), a Trop-2–directed antibody–drug conjugate, is approved for patients with mTNBC who have received ≥ 2 systemic therapies (≥ 1 in the metastatic setting) based on the ASCENT study (NCT02574455). The current study describes real-world SG use and outcomes in patients with mTNBC in the United States.

Methods
This retrospective, observational study included adult patients with mTNBC from the ConcertAI Patient360™ database who received SG in the second line (2L) and later from April 2020 to May 2022. SG use patterns, effectiveness, and tolerability are described.

Results
This analysis included 230 patients (median age 60 years, 26% Black, 17% with ECOG performance status ≥ 2, 66% in community settings; median of 2 prior lines of treatment in the metastatic setting); median follow-up was 7.2 months. Median (95% CI) real-world overall survival was 10.0 (8.3–11.1) months for all patients and 13.9 (9.8-not estimable) months in the 2L subgroup (n = 77). Granulocyte-colony stimulating factor (G-CSF) was administered concomitantly with SG in 134 (58%) patients; 35 (15%) received G-CSF for the first time. Median (IQR) time from SG start to G-CSF use was 8.5 (8.0–29.0) days. Seventeen (7%) patients discontinued SG due to toxicity.

Conclusions
Using a real-world, ethnically diverse population of patients with mTNBC presenting with poor prognosis, these data reinforced the findings from ASCENT. In routine clinical practice, SG is an effective treatment in the 2L setting, consistent with treatment guidelines.
Assessment of risks associated with development of river meandering under climate change using a physics-based free-meandering model
Authors: Masuya Shigekazu , Inoue Takuya , Iwasaki Toshiki , Kido Riho , Ogawa Kohei , Shimizu Yasuyuki 
Published: June 2024

AbstractRecent increases in heavy rainfall events, which may have resulted from climate change, have caused various natural water- and sediment-related disasters. A typical sediment-related disaster in a steep gravel-bed river is extreme bank erosion and subsequent meander development, damaging residential areas and infrastructure along the river. Assessing the bank erosion rate and its future changes under climate change is essential to prevent such severe disasters. Here, we propose a simple but useful framework for this purpose using a physics-based numerical model of free meandering and a large dataset of flood hydrographs generated from climate and runoff models. First, numerical experiments on meandering development were conducted using a two-dimensional morphodynamic model of free meandering. The results indicate that meander dynamics could reach a dynamic equilibrium state under several hydraulic and channel geometry conditions, and the characteristics of the simulated meandering channel were reasonably consistent with the field data. The meander amplitude of this state was positively correlated with the steady discharge; therefore, the increase in flow discharge may have an important effect on river dynamics under climate change. To quantify this effect, we combined a simple predictor of meander amplitude derived from a numerical experiment with a flood hydrograph dataset for current and future climatic conditions. The results suggest that the meander amplitude increased significantly for the same probability of occurrence; therefore, the risk of riverbank erosion due to river meandering will increase significantly under future climate conditions.
Experimental and numerical study of unsteady flows in a compound open channel
Authors: Kaddi Yassine , Proust Sébastien , Faure Jean-Baptiste , Cierco François-Xavier 
Published: June 2024

AbstractUnsteady flows are investigated in a compound open-channel flume, consisting of a Main Channel (MC) and an adjacent Flood Plain (FP). Two types of inflow hydrographs are studied, i.e., a discharge hydrograph with, at any time: a slightly unbalanced inflow partition between MC and FP (Case I); and a noticeably unbalanced inflow partition (Case II). Ensemble averages of the time-varying discharges, water depths and velocities are estimated based on 100 successive runs. The main focus of the experimental study is on assessing (i) the time-varying lateral discharge and depth-averaged Reynolds stress at the MC/FP interface, and (ii) the influence of the inflow partition on the downstream flow parameters. The experimental flows are then simulated using a 1D (one-dimensional) code that was adapted to implement the 1D+ Independent Sub-sections Model (ISM) (Proust et al. in Water Resour Res 45:1–16, 2009). The numerical study aims at validating the ISM under unsteady flow conditions, using classical 1D simulations as benchmark. It is experimentally found that 90 successive runs are required to get convergence of the ensemble averages of sub-section discharges and flow depth, while interfacial velocity is not fully converged after 100 runs. The influence of the inflow partition on the downstream parameters is felt along the whole flume. The ISM simulations are closer to the measurements than the classical 1D simulations. The ISM can accurately predict the time-varying flow depths and interfacial lateral discharge, and can approximate the interfacial Reynolds stresses.
Optimizing Three-Dimensional Stencil-Operations on Heterogeneous Computing Environments
Authors: Herrmann Nina , Dieckmann Justus , Kuchen Herbert 
Published: June 2024

AbstractComplex algorithms and enormous data sets require parallel execution of programs to attain results in a reasonable amount of time. Both aspects are combined in the domain of three-dimensional stencil operations, for example, computational fluid dynamics. This work contributes to the research on high-level parallel programming by discussing the generalizable implementation of a three-dimensional stencil skeleton that works in heterogeneous computing environments. Two exemplary programs, a gas simulation with the Lattice Boltzmann method, and a mean blur, are executed in a multi-node multi-graphics processing units environment, proving the runtime improvements in heterogeneous computing environments compared to a sequential program.
Sedimentation of large, soluble proteins up to 140 kDa for 1H-detected MAS NMR and 13C DNP NMR – practical aspects
Authors: Bell Dallas , Lindemann Florian , Gerland Lisa , Aucharova Hanna , Klein Alexander , Friedrich Daniel , Hiller Matthias , Grohe Kristof , Meier Tobias , van Rossum Barth , Diehl Anne , Hughes Jon , Mueller Leonard J. , Linser Rasmus , Miller Anne-Frances , Oschkinat Hartmut 
Published: June 2024

AbstractSolution NMR is typically applied to biological systems with molecular weights < 40 kDa whereas magic-angle-spinning (MAS) solid-state NMR traditionally targets very large, oligomeric proteins and complexes exceeding 500 kDa in mass, including fibrils and crystalline protein preparations. Here, we propose that the gap between these size regimes can be filled by the approach presented that enables investigation of large, soluble and fully protonated proteins in the range of 40–140 kDa. As a key step, ultracentrifugation produces a highly concentrated, gel-like state, resembling a dense phase in spontaneous liquid-liquid phase separation (LLPS). By means of three examples, a Sulfolobus acidocaldarius bifurcating electron transfer flavoprotein (SaETF), tryptophan synthases from Salmonella typhimurium (StTS) and their dimeric β-subunits from Pyrococcus furiosus (PfTrpB), we show that such samples yield well-resolved proton-detected 2D and 3D NMR spectra at 100 kHz MAS without heterogeneous broadening, similar to diluted liquids. Herein, we provide practical guidance on centrifugation conditions and tools, sample behavior, and line widths expected. We demonstrate that the observed chemical shifts correspond to those obtained from µM/low mM solutions or crystalline samples, indicating structural integrity. Nitrogen line widths as low as 20–30 Hz are observed. The presented approach is advantageous for proteins or nucleic acids that cannot be deuterated due to the expression system used, or where relevant protons cannot be re-incorporated after expression in deuterated medium, and it circumvents crystallization. Importantly, it allows the use of low-glycerol buffers in dynamic nuclear polarization (DNP) NMR of proteins as demonstrated with the cyanobacterial phytochrome Cph1.
Neurosurgical resection of multiple brain metastases: outcomes, complications, and survival rates in a retrospective analysis
Authors: Niedermeyer Sebastian , Schmutzer-Sondergeld M. , Weller J. , Katzendobler S. , Kirchleitner S. , Forbrig R. , Harter P. N. , Baumgarten L. V. , Schichor C. , Stoecklein V. , Thon N. 
Published: June 2024

Abstract
Purpose
This study investigates the outcomes of microsurgical resection of multiple brain metastasis (BMs).

Methods
This retrospective, monocentric analysis included clinical data from all consecutive BM patients, who underwent simultaneous resection of ≥ 2 BMs between January 2018 and May 2023. Postoperative neurological and functional outcomes, along with perioperative complications, as well as survival data were evaluated.

Results
A total of 47 patients, with a median age of 61 years (IQR 48–69), underwent 73 craniotomies (median 2; range 1–3) for resection of 104 BMs. Among patients, 80.8% presented with symptomatic BMs, causing focal neurological deficits in 53% of cases. Gross total resection was achieved in 87.2% of BMs. Karnofsky Performance Scale (KPS) scores improved in 42.6% of patients, remained unchanged in 46.8%, and worsened in 10.6% after surgery. Perioperative complications were observed in 29.8% of cases, with transient complications occurring in 19.2% and permanent deficits in 10.6%. The 30-days mortality rate was 2.1%. Logistic regression identified eloquent localization (p = 0.036) and infratentorial craniotomy (p = 0.018) as significant predictors of postoperative complications. Concerning overall prognosis, patients with permanent neurological deficits post-surgery (HR 11.34, p = 0.007) or progressive extracranial disease (HR: 4.649; p = 0.006) exhibited inferior survival.

Conclusion
Microsurgical resection of multiple BMs leads to clinical stabilization or functional improvement in most patients. Although transient complications do not affect overall survival, the presence of persistent neurological deficits (> 3 months post-surgery) and progressive extracranial disease negatively impact overall survival. This highlights the importance of careful patient selection for resection of multiple BMs.