bluuebunny/crossref_metadata_2025_split huggingface dataset:
Xai-driven knowledge distillation of large language models for efficient deployment on low-resource devices
Authors: Cantini Riccardo , Orsino Alessio , Talia Domenico 
Published: May 2024

AbstractLarge Language Models (LLMs) are characterized by their inherent memory inefficiency and compute-intensive nature, making them impractical to run on low-resource devices and hindering their applicability in edge AI contexts. To address this issue, Knowledge Distillation approaches have been adopted to transfer knowledge from a complex model, referred to as the teacher, to a more compact, computationally efficient one, known as the student. The aim is to retain the performance of the original model while substantially reducing computational requirements. However, traditional knowledge distillation methods may struggle to effectively transfer crucial explainable knowledge from an LLM teacher to the student, potentially leading to explanation inconsistencies and decreased performance. This paper presents DiXtill, a method based on a novel approach to distilling knowledge from LLMs into lightweight neural architectures. The main idea is to leverage local explanations provided by an eXplainable Artificial Intelligence (XAI) method to guide the cross-architecture distillation of a teacher LLM into a self-explainable student, specifically a bi-directional LSTM network.Experimental results show that our XAI-driven distillation method allows the teacher explanations to be effectively transferred to the student, resulting in better agreement compared to classical distillation methods,thus enhancing the student interpretability. Furthermore, it enables the student to achieve comparable performance to the teacher LLM while also delivering a significantly higher compression ratio and speedup compared to other techniques such as post-training quantization and pruning, which paves the way for more efficient and sustainable edge AI applications
Establishment of primary prostate epithelial and tumorigenic cell lines using a non-viral immortalization approach
Authors: Lange Simon , Kuntze Anna , Wüstmann Neele , Reckers Theresa , Humberg Verena , Dirks Wilhelm G. , Huss Sebastian , Vieler Julia , Schrader Andres Jan , Bögemann Martin , Schlack Katrin , Bernemann Christof 
Published: May 2024

Abstract
Background
Research on prostate cancer is mostly performed using cell lines derived from metastatic disease, not reflecting stages of tumor initiation or early progression. Establishment of cancer cell lines derived from the primary tumor site has not been described so far. By definition, cancer cells are able to be cultured indefinitely, whereas normal epithelial cells undergo senescence in vitro. Epithelial cells can be immortalized, accomplished by using viral integration of immortalization factors. Viral approaches, however, might be impaired by regulatory and safety issues as well as random integration into regulatory genetic elements, modifying precise gene expression. We intend to use surgical specimen of prostate cancer patients to (i) prove for establishment of cancer cell lines, and (ii) perform non-viral, Sleeping Beauty (SB) transposase-based immortalization of prostate epithelial cells.

Methods
Radical prostatectomy samples of prostate cancer patients (n = 4) were dissociated and cultured in vitro. Cells were cultivated either without or after non-viral, Sleeping-Beauty transposase-based stable transfection with immortalization factors SV40LT and hTERT. Established cell lines were analyzed in vitro and in vivo for characteristics of prostate (cancer) cells.

Results
Initial cell cultures without genetic manipulation underwent senescence within ≤ 15 passages, demonstrating inability to successfully derive primary prostate cancer cell lines. By using SB transposase-based integration of immortalization factors, we were able to establish primary prostate cell lines. Three out of four cell lines displayed epithelial characteristics, however without expression of prostate (cancer) characteristics, e.g., androgen receptor. In vivo, one cell line exhibited tumorigenic potential, yet characteristics of prostate adenocarcinoma were absent.

Conclusion
Whereas no primary prostate cancer cell line could be established, we provide for the first-time immortalization of primary prostate cells using the SB transposase system, thereby preventing regulatory and molecular issues based on viral immortalization approaches. Although, none of the newly derived cell lines demonstrated prostate cancer characteristics, tumor formation was observed in one cell line. Given the non-prostate adenocarcinoma properties of the tumor, cells have presumably undergone oncogenic transformation rather than prostate cancer differentiation. Still, these cell lines might be used as a tool for research on prostate cancer initiation and early cancer progression.
EEG source imaging of hand movement-related areas: an evaluation of the reconstruction and classification accuracy with optimized channels
Authors: Soler Andres , Giraldo Eduardo , Molinas Marta 
Published: May 2024

AbstractThe hand motor activity can be identified and converted into commands for controlling machines through a brain-computer interface (BCI) system. Electroencephalography (EEG) based BCI systems employ electrodes to measure the electrical brain activity projected at the scalp and discern patterns. However, the volume conduction problem attenuates the electric potential from the brain to the scalp and introduces spatial mixing to the signals. EEG source imaging (ESI) techniques can be applied to alleviate these issues and enhance the spatial segregation of information. Despite this potential solution, the use of ESI has not been extensively applied in BCI systems, largely due to accuracy concerns over reconstruction accuracy when using low-density EEG (ldEEG), which is commonly used in BCIs. To overcome these accuracy issues in low channel counts, recent studies have proposed reducing the number of EEG channels based on optimized channel selection. This work presents an evaluation of the spatial and temporal accuracy of ESI when applying optimized channel selection towards ldEEG number of channels. For this, a simulation study of source activity related to hand movement has been performed using as a starting point an EEG system with 339 channels. The results obtained after optimization show that the activity in the concerned areas can be retrieved with a spatial accuracy of 3.99, 10.69, and 14.29 mm (localization error) when using 32, 16, and 8 channel counts respectively. In addition, the use of optimally selected electrodes has been validated in a motor imagery classification task, obtaining a higher classification performance when using 16 optimally selected channels than 32 typical electrode distributions under 10–10 system, and obtaining higher classification performance when combining ESI methods with the optimal selected channels.
Comparative investigation on the phenolic compounds and antioxidant capacity of walnut kernel from different drying methods
Authors: Qingyang Li , Shuting Wang , Ruohui Wang , Danyu Shen , Runhong Mo , Fubin Tang , Yihua Liu 
Published: May 2024

AbstractDrying techniques are being used more and more to extend the shelf life of industrial products. Drying could influnce the content of phenolics in food and their antioxidant activity. This study estimated the effects of different drying methods (freeze drying (FD), gradient hot air drying (GHD), and constant hot air drying (CHD)) on phenolic profiles and antioxidant activities in walnut kernels. With a maximum content of 3.61 mg g−1, GHD was found to be the most effective in preserving total phenols, while CHD and FD had maximum contents of 2.66 mg g−1 and 1.96 mg g−1, respectively. The concentration of most monomeric phenols detected in the kernels increased with temperature, particularly in the free and bound forms. Gallic acid (free form) levels in GHD2 (194.54 µg g−1) were 55.77 and 60.08 times higher, respectively, than in FD and CHD. GHD dried walnuts had higher antioxidant activity than FD and CHD dried walnuts. Furthermore, bioinformatics analysis revealed three key metabolic pathways associated with the mechanisms underlying drying changes. The GHD technique, according to these findings, is a better choice for drying walnut in order to preserve its phenolics and antioxidant activity.

Graphical Abstract
Strategies and achievements in controlling and eliminating schistosomiasis from Egypt
Authors: El-Kassas Mohamed , Sheemy Reem El , Elbadry Mohamed 
Published: May 2024

AbstractSchistosomiasis is an old parasitic disease in Egypt primarily caused by Schistosoma mansoni, transmitted through infected water canals, and disproportionately affects rural areas. Despite substantial reductions in the disease prevalence over the years, it still affects more than 5% of the population in some governorates, highlighting the need for sustained control efforts. Among the recent control measures: (a) mass drug administration with large-scale, biannual administration of praziquantel, which remains the cornerstone of the control program targeting the interruption of vector transmission cycles. (b) Improving disease diagnostics, including point-of-care tests, which facilitate early detection and case management, particularly in remote areas. (c) Snail control using targeted mollusciciding aims to reduce parasite transmission by controlling intermediate snail hosts. And (d) behavioral change communication focusing on raising awareness regarding hygiene practices and safe water access.Even if control attempts have shown positive results, several challenges still exist, including (a) drug resistance, especially to praziquantel, the most commonly used drug, which calls for ongoing observation and monitoring. (b) Sustainability of funding to avoid program disruptions and setbacks. And (c) social and environmental factors like poverty, poor sanitation, and access to clean water. The transition from disease control to elimination requires meticulous planning and vigilance. Robust surveillance systems, enhanced case management, and continued community engagement are vital for such elimination. Strengthening research on drug resistance, snail control methods, and innovative diagnostics would further support elimination efforts. This report aims to address the most recent data regarding the prevalence and control measures for schistosomiasis in Egypt and provide the information required to lead the transition from disease control to elimination.
High-performance work systems and organizational ambidexterity: the mediating role of knowledge management systems—evidence from the Egyptian public-telecommunication sector
Authors: Elashry Mona Moustafa , Kortam Wael Abd elrazik , Ali Tarek Mohamed 
Published: May 2024

Abstract
Purpose
The purpose of this study is to examine the mediating role of the quality-based knowledge management systems (KMSs) in explaining the relationships between AMO-based high-performance work systems (HPWSs) and organizational ambidexterity (OA).

Design/methodology/approach
Using cross-sectional survey, the authors collected data from 277 employees working at the Egyptian public-telecommunication sector and analyzed the hypothesized model using the partial least square structural equation modeling technique. Interviews were conducted with 39 key positions and mirrored against the quantitative data. The qualitative data were analyzed using the thematic analysis technique.

Findings
The authors found that the HPWSs dimensions (i.e., ability and opportunity-enhancing practices) explain the OA level. The HPWSs dimensions (i.e., ability, motivation, and opportunity-enhancing practices) have a significant positive effect on the KMSs quality. The KMSs (i.e., system, service, and information quality) have a significant positive effect on OA and mediate the relationship between HPWSs and OA.

Originality/value
This study is among the first to add significant information on how the quality-based KMSs (as mediator) explain the complex relationship between HPWSs dimensions and OA.

Research limitations/implications
Limited attention was paid to investigating the OA enablers. This study bridges the aforementioned research gap by providing in-depth explanations on how the working systems atmosphere emphasizing ability, motivation, and opportunity-enhancing practices alongside the quality-based KMSs enable OA.

Practical/managerial implication
The findings provide the decision makers in public-telecom sector with a clear guideline for achieving ambidexterity in turbulent business environment.
Visualizing victory: the role of imagery in empowering athletes battling obsessive-compulsive disorder
Authors: Raboin Sydney 
Published: May 2024

Abstract
Obsessive-Compulsive Disorder (OCD) is one of the most common mental health disorders that can make activities of daily life more challenging, as well as adversely impact wellbeing. OCD is an anxiety disorder that presents as uncontrollable and unsolicited thoughts, mental images, and sensations, followed by obsession over them and an irresistible need to complete compulsive behaviors in attempt to challenge them and find relief. It causes fear of both one’s own thoughts and the world around them. OCD shows its place in the athletic realm where it can impact an athlete’s mentality, attention, behaviors, and goal orientation, which may potentially hinder the enhancement and proficiency of their skills and abilities, and create more difficulty for maintaining stability, responding to internal and external stressors, and exhibiting competency. Mental imagery techniques provide fundamental tools and coping mechanisms that can aid in the management and treatment of OCD; strengthening control of the mind and body and reducing the prevalence and severity of symptoms by enabling more attentiveness, enhancing executive functioning, promoting more effective responses to stressors, and benefiting personal growth. This paper first discusses OCD symptoms, characteristic identifiers, pathophysiology, diagnostic criteria, prognostic expectations, epidemiology in the general population and athlete population, pathogenesis in athletes, as well as the possible challenges associated with OCD and the potential to overcome them. Secondly, this paper defines mental imagery, the role of imagery as therapy, and how imagery can be used to combat OCD. This paper concludes with the review of imagery-based psychotherapy for OCD and educational sport psychology imagery-based interventions for OCD that can support the wellness of an athlete with OCD, encourage their development, and make them more equipped to achieve success.
Y luego un tiburón blanco ha abrido la boca: Spanish children’s overregularization of irregular past participles
Authors: Baker Martínez Elisabeth 
Published: May 2024

Abstract
The current study investigates the influence of Age, Lexical frequency, and Language background on children’s overregularization of irregular past participles (e.g., ponido ‘put’, cf. puesto). A total of 536 past participles used in compound tenses (e.g., he escrito ‘I have written’) were extracted from child speech in online corpora from both monolingual Spanish (N = 45) and Spanish-English bilingual children (N = 2) between the ages of 3;0 and 6;11. The children overregularized 7 % of their past participles and did so more often with low-frequency participles like escrito ‘written’ than with high-frequency ones like hecho ‘done/made’. Additionally, Spanish-English bilinguals overregularized more than the monolinguals, and the bilinguals’ overregularizations persisted with age while the monolingual children’s rates decreased with age. These results demonstrate that both monolingual and bilingual children overregularize irregular past participles in the structures of interest and that their overregularizations are mediated by lexical frequency. Further, these results suggest that children must be exposed to enough examples of irregular forms before they stop applying the regular pattern. While the monolingual children who were exposed to extended amounts of Spanish retreated from participle overregularization with age, bilinguals’ rates of overregularization persisted through the ages studied. These findings indicate that children from both speaker groups follow a similar acquisitional path of irregular past participles; however, language experience predicts their rates of overregularization, and the timespan required to master the irregulars.
SAYAN-YENISEI POTENTIAL PETROLEUM AREA AND ITS RESOURCE POTENTIAL
Authors: Губин И.А. , Конторович А.Э. , Бурштейн Л.М. , Константинова Л.Н. , Кузнецова Е.Н. , Моисеев С.А. , Сафронов П.И. 
Published: May 2024

Выполнен анализ результатов современных региональных сейсморазведочных работ и глубокого бурения в Присаяно-Енисейской перспективной нефтегазоносной области и на прилегающих тер­риториях Лено-Тунгусской нефтегазоносной провинции. Построены структурные карты по опорным отражающим горизонтам рифея, венда и нижнего кембрия, а также карты толщин рифейского и вендского­ терригенного сейсмогеологических комплексов. Построена тектоническая карта венд-палеозойского структурного яруса Присаяно-Енисейской синеклизы. Выполнено нефтегазогеологическое районирование Присаяно-Енисейской перспективной нефтегазоносной области, выделено восемь перспективных нефтегазоносных районов и выполнена количественная оценка перспектив нефтегазоносности. Начальные суммарные геологические ресурсы углеводородов Присаяно-Енисейской перспективной нефтегазоносной области оценены в 3 млрд 231 млн т УУВ, в том числе газа в 3 трлн 39 млрд м3 и конденсата в 192.7 млн т. Показано, что за 15—20 лет в Присаяно-Енисейской перспективной нефтегазоносной области могут быть подготовлены значительные запасы газа — до 1 трлн м3. Предложено рассматривать в качестве будущего центра газохимии и переработки газа пос. Богучаны.
This study presents the results of recent regional seismic exploration and deep drilling efforts in the Sayan–Yenisei syneclise and adjacent areas of the Lena–Tunguska petroleum province. These results were used to build a series of structure maps for Riphean, Vendian and Lower Cambrian reflectors; thickness maps of the Riphean and Vendian terrigenous geoseismic sequences within the syneclise, and a tectonic map of the Vendian–Paleozoic structural stage of the Sayan–Yenisei syneclise. The proposed oil and gas geological zoning of the Sayan–Yenisei potential petroleum area enabled us to identify eight potential petroleum regions and perform a quantitative assessment of the hydrocarbon potential. The original in-place resources of the Sayan–Yenisei potential petroleum area are estimated to be 3 billion 231 million tons of hydrocarbon equivalent, including 3 trillion 39 billion m3 of gas and 192.7 million tons of condensate. It is shown that over next 15–20 years, up to 1 trillion m3 gas reserves can be explored in the Sayan–Yenisei potential petroleum area. It is proposed to consider the Boguchany village as a large gas conversion and helium production center.
Role Of In- Situ Rutin Flavonoid Consisted Myristica Fragrans Silver Nano Particles (MF-Ag-Nps) Against Escherichia Coli and Bacillus Subtilis
Authors: Satyasri Sulapu Manasa Gayathri , Thummaneni Chandana , Hanuman Madduri , Lavu Rama Devi , Vangalapati Meena 
Published: May 2024

Most microbiological growth inhibitors are toxic and chemical solvents are harmful for human health. Copper, silver, and gold metallic nanoparticles have several uses in biotechnology and medicinal research. MF-Ag-NPs(silver nanoparticles)are potent anti-inflammatory, anti-proliferative, and anti-microbial agents. The purpose of this study was to biogenically generate silver nanoparticles by extracting rutin from nutmeg, a seed from the Myristica fragrans plant. In order to create Myristica fragrans MF-Ag-NPs, silver nitrate was dissolved in the extract. The transformation of the colour from dark brown to pale brown confirmed the conversion of Ag+ to Ag°. FTIR, EDX, and SEM were used to describe them. Images from scanning electron microscopy demonstrate the presence of silver nanoparticles between 20 and 300 nm in size. The presence of oxygen and silver, as well as the metal's oxidation state, were confirmed by EDAX analysis. The nanoparticles' distinctive functional groups were discovered using FTIR spectroscopy. The antibacterial activity of Myristica fragrans seed extract was assessed. The extract from the seeds of Myrsitica fragrans exhibited the strongest antibacterial properties. These findings imply that antibacterial MF-Ag-NPs phyto-formulated with nutmeg extracts might be used to treat microbial infections in the future.
Predicting the impact of water transport on carbonation-induced corrosion in variably saturated reinforced concrete
Authors: Korec Evžen , Mingazzi Lorenzo , Freddi Francesco , Martínez-Pañeda Emilio 
Published: May 2024

AbstractA modelling framework for predicting carbonation-induced corrosion in reinforced concrete is presented. The framework constituents include a new model for water transport in cracked concrete, a link between corrosion current density and water saturation, and a theory for characterising concrete carbonation. The theoretical framework is numerically implemented using the finite element method and model predictions are extensively benchmarked against experimental data. The results show that the model is capable of accurately predicting carbonation progress, as well as wetting and drying of cracked and uncracked concrete, revealing a very good agreement with independent experiments from a set of consistent parameters. In addition, insight is gained into the evolution of carbonation penetration and corrosion current density under periodic wetting and drying conditions. Among others, we find that cyclic wetting periods significantly speed up the carbonation progress and that the induced corrosion current density is very sensitive to concrete saturation.
papel do tutor na consolidação da aprendizagem na EAD:
Authors: SALDANHA DE SIQUEIRA KLEBER 
Published: May 2024

A educação a distância tem promovido novas formas de aprender e ensinar por meio da mediação tecnológica e das diferentes estratégias pedagógicas intrínsecas a esses recursos. Nesse cenário, o papel do tutor na consolidação da aprendizagem tem sido alvo de discussão na áreaeducacional, dada a relevância desse profissional na implementação de ações voltadas para a manutenção da EaD. Este artigo, configurado na forma de um estudo bibliográfico de natureza narrativa-qualitativa, buscarefletir sobre o papel do tutor na EaD dentro da conjuntura atual dessa modalidade, abordando os principais limites, desafios, habilidades e perspectivas que tornam esse profissional indispensável. Para isso, foramconsultados os portais acadêmicos de acesso livre Scielo e Oasisbr, sendo empregados descritores de busca e critérios de inclusão e exclusão para a seleção da base bibliográfica desta pesquisa, composta por trabalhos publicados entre 2013 e 2023. Ao final deste trabalho, a partir das reflexões produzidas, foi possível identificar o perfil de atuação do tutor para uma mediação eficaz no processo de ensino e aprendizagem, revelando quaisposturas, habilidades e competências esse profissional deve apresentar para o exercício de sua função na atualidade.