bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pour une analyse dramaturgique des rôles du conjoint dans l'expatriation
Authors: Davoine Eric , Ravasi Claudio , Cudré-Mauroux Christel 
Published: October 2011

Résumé Dans cet article, nous nous intéressons au rôle social du conjoint d’expatrié dans le cadre de l’expatriation. De nombreux chercheurs soulignent l’importance du conjoint pour la réussite ou l’échec de l’expatriation. Certains experts placent même le comportement du conjoint comme premier facteur de réussite de l’expatriation. Aujourd’hui, il est de plus en plus difficile pour les multinationales d’ignorer l’importance des conjoints et de nier les attentes de rôle social et professionnel que l’organisation leur adresse. Dans cet article, nous nous intéressons, avec une approche « dramaturgique », d’inspiration « goffmanienne », à ces attentes de rôle. Nous les étudions avec un cas exemplaire, celui des conjoints du personnel diplomatique et consulaire du Ministère suisse des Affaires Étrangères. Quarante conjoints, hommes et femmes, ont été interrogés dans le cadre de notre enquête. Nous présentons de manière structurée les principaux répertoires identifiés, en détaillant les différents sous-répertoires qui peuvent être mobilisés pour interpréter le rôle de conjoint.
Coordinated Regulation of Lymph Node Vascular–Stromal Growth First by CD11c+ Cells and Then by T and B Cells
Authors: Chyou Susan , Benahmed Fairouz , Chen Jingfeng , Kumar Varsha , Tian Sha , Lipp Martin , Lu Theresa T. 
Published: October 2011

Abstract
Lymph node blood vessels play important roles in the support and trafficking of immune cells. The blood vasculature is a component of the vascular–stromal compartment that also includes the lymphatic vasculature and fibroblastic reticular cells (FRCs). During immune responses as lymph nodes swell, the blood vasculature undergoes a rapid proliferative growth that is initially dependent on CD11c+ cells and vascular endothelial growth factor (VEGF) but is independent of lymphocytes. The lymphatic vasculature grows with similar kinetics and VEGF dependence, suggesting coregulation of blood and lymphatic vascular growth, but lymphatic growth has been shown to be B cell dependent. In this article, we show that blood vascular, lymphatic, and FRC growth are coordinately regulated and identify two distinct phases of vascular–stromal growth—an initiation phase, characterized by upregulated vascular–stromal proliferation, and a subsequent expansion phase. The initiation phase is CD11c+ cell dependent and T/B cell independent, whereas the expansion phase is dependent on B and T cells together. Using CCR7−/− mice and selective depletion of migratory skin dendritic cells, we show that endogenous skin-derived dendritic cells are not important during the initiation phase and uncover a modest regulatory role for CCR7. Finally, we show that FRC VEGF expression is upregulated during initiation and that dendritic cells can stimulate increased fibroblastic VEGF, suggesting the scenario that lymph node-resident CD11c+ cells orchestrate the initiation of blood and lymphatic vascular growth in part by stimulating FRCs to upregulate VEGF. These results illustrate how the lymph node microenvironment is shaped by the cells it supports.
La famille dans tous ces États : France, Géorgie, Lituanie, Russie
Authors: Blum Alain , Lefèvre Cécile , Sebille Pascal , Badurashvili Irina , Régnier-Loilier Arnaud , Stankundétriene Vlada , Sinyavskaya Oxana 
Published: October 2011

Résumé :	Ce numéro spécial est consacré à l’étude des transformations familiales récentes survenues en France, Géorgie, Lituanie et Russie. Celles-ci s’articulent autour de trois ensembles de facteurs majeurs des comportements démographiques : le premier est d’ordre anthropologique et ressort aux relations intra-familiales ; le deuxième est politique, l’histoire de chacun de ces pays étant particulière ; le troisième est économique et social : il contraint ou libère les trajectoires démographiques, étant lui-même la combinaison de profondes tendances transnationales et nationales. Cet ordonnancement a surtout une valeur heuristique et non démonstrative. Il sert à replacer les études qui suivent dans le cadre général des transformations démographiques et offre un regard sur les principales dynamiques observées à partir d’indicateurs synthétiques et de mesures issues des enquêtes « Générations et genre » (GGS : Generations and Gender Surveys ) menées entre 2004 et 2006 sur la base d’un questionnaire de référence commun (voir et ) dans les quatre pays retenus ici.
Quality Improvement in Cytology: Where Do We Go From Here?
Authors: Renshaw Andrew A. 
Published: October 2011

Context.—Cytology is a success because of the many quality controls used to ensure the accuracy of its results. Nevertheless, additional information is becoming available to the cytologist, often from untraditional sources, and the best way to use that information to improve the quality of cytology is not yet known.Objective.—To review ways to use new information to improve the quality of cytology.Data Sources.—Review of relevant literature.Results.—Information contained in many sources can be used in new ways to improve the quality of cytology. These include the timing of cytologic and histologic correlation, electronic medical records, workload information, prior aspirations, and molecular tests.Conclusions.—To maintain their high standard of excellence, cytologists should seek to define the most appropriate way to incorporate this new information into their interpretation of individual cases.
Polymorphic variants at 10q25.3 and 17q22 loci and the risk of non‐syndromic cleft lip and palate in the polish population
Authors: Mostowska Adrianna , Hozyasz Kamil K. , Wojcicka Karolina , Biedziak Barbara , Jagodzinski Pawel P. 
Published: October 2011

AbstractBACKGROUNDNon‐syndromic cleft lip and palate (CLP) is one of the most common birth defects. Recent genome‐wide association studies (GWAS) have identified several novel risk loci associated with this craniofacial anomaly. Therefore, the objective of this report was to investigate the contribution of the top seven polymorphisms reaching genome‐wide statistical significance in GWAS analyses in the Polish population.METHODS and RESULTSNucleotide variants located at chromosomal regions 1p22.1, 10q25.3, 17q22, and 20q12 were tested in a group of 206 patients with nonsyndromic CLP and a properly matched control group. Significant results, which persisted even after Bonferroni correction (p < 0.0071), were observed for polymorphisms located at 10q25.3 (rs7078160 and rs4752028) and 17q22 (rs227731). Under a recessive model, both rs7078160 and rs4752028 were associated with a greater than fourfold increase in the risk of CLP (odds ratio [OR] = 4.536; 95% confidence interval [CI], 1.678–12.265; p = 0.0012 and OR = 4.573; 95% CI, 1.817–11.512; p = 0.0004, respectively). Polymorphism rs227731 increased the risk of CLP when analyzed under a dominant model (OR = 1.732; 95% CI, 0.184–2.253; p = 0.0044). Borderline association was alsoidentified for the 1p22.1 locus (rs481931). Moreover, 10q25.3 haplotypes were significantly associated with a susceptibility to CLP.CONCLUSIONOur evaluation study confirmed a substantial association of polymorphisms located at chromosomal regions 10q25.3 and 17q22 with nonsyndromic CLP in the Polish population. Birth Defects Research (Part A), 2012. © 2011 Wiley Periodicals, Inc.
Health care expenditures among children with and those without spina bifida enrolled in Medicaid in North Carolina
Authors: Cassell Cynthia H. , Grosse Scott D. , Thorpe Phoebe G. , Howell Eleanor E. , Meyer Robert E. 
Published: October 2011

AbstractBACKGROUNDNational data on health care use among children with special needs are limited and do not address children with spina bifida (SB). One recent study examined health care costs during 2003 among privately insured individuals with SB. Our objective was to compare health care use and expenditures among publicly insured children with SB to children without a major birth defect and among children with SB with and without hydrocephalus.METHODSData from the North Carolina Birth Defects Monitoring Program and Medicaid were linked to identify continuously enrolled children with SB (case children) and children without a major birth defect (control children) born from 1995 to 2002. Medicaid expenditures per child for medical, inpatient, outpatient, dental, well‐child care, developmental/behavioral services, and home health for those aged 0 to 4 years old were calculated for case and control children and for case children with and without hydrocephalus.RESULTSOf 373 case children who survived infancy, 205 (55%) were enrolled in Medicaid. Expenditures were assessed for 144 case and 5674 control children aged 0 to 4 years old continuously enrolled in Medicaid. During infancy, mean expenditure was $33,135 per child with SB and $3900 per unaffected child. The biggest relative expenditures were for developmental/behavioral services (82 times higher for case than control child [$1401 vs. $17]) and home health services (20 times higher [$821 vs. $41]). Average expenditure for an infant with SB and hydrocephalus was 2.6 times higher than an infant with SB without hydrocephalus ($40,502 vs. $15,699).CONCLUSIONSExpenditure comparisons by SB subtype are important for targeting health care resources. Birth Defects Research (Part A), 2011. © 2011 Wiley Periodicals, Inc.
Acquired self‐control of insula cortex modulates emotion recognition and brain network connectivity in schizophrenia
Authors: Ruiz Sergio , Lee Sangkyun , Soekadar Surjo R. , Caria Andrea , Veit Ralf , Kircher Tilo , Birbaumer Niels , Sitaram Ranganatha 
Published: October 2011

AbstractReal‐time functional magnetic resonance imaging (rtfMRI) is a novel technique that has allowed subjects to achieve self‐regulation of circumscribed brain regions. Despite its anticipated therapeutic benefits, there is no report on successful application of this technique in psychiatric populations. The objectives of the present study were to train schizophrenia patients to achieve volitional control of bilateral anterior insula cortex on multiple days, and to explore the effect of learned self‐regulation on face emotion recognition (an extensively studied deficit in schizophrenia) and on brain network connectivity. Nine patients with schizophrenia were trained to regulate the hemodynamic response in bilateral anterior insula with contingent rtfMRI neurofeedback, through a 2‐weeks training. At the end of the training stage, patients performed a face emotion recognition task to explore behavioral effects of learned self‐regulation. A learning effect in self‐regulation was found for bilateral anterior insula, which persisted through the training. Following successful self‐regulation, patients recognized disgust faces more accurately and happy faces less accurately. Improvements in disgust recognition were correlated with levels of self‐activation of right insula. RtfMRI training led to an increase in the number of the incoming and outgoing effective connections of the anterior insula. This study shows for the first time that patients with schizophrenia can learn volitional brain regulation by rtfMRI feedback training leading to changes in the perception of emotions and modulations of the brain network connectivity. These findings open the door for further studies of rtfMRI in severely ill psychiatric populations, and possible therapeutic applications. Hum Brain Mapp, 2013. © 2011 Wiley Periodicals, Inc.
Fiber tract‐specific white matter lesion severity Findings in late‐life depression and by AGTR1 A1166C genotype
Authors: Taylor Warren D. , Zhao Zheen , Ashley‐Koch Allison , Payne Martha E. , Steffens David C. , Krishnan Ranga R. , Hauser Elizabeth , MacFall James R. 
Published: October 2011

AbstractPast work demonstrated that late‐life depression is associated with greater severity of ischemic cerebral hyperintense white matter lesions, particularly frontal lesions. However, these lesions are also associated with other neuropsychiatric deficits, so these clinical relationships may depend on which fiber tracts are damaged. We examined the ratio of lesion to nonlesioned white matter tissue within multiple fiber tracts between depressed and nondepressed elders. We also sought to determine if the AGTR1 A1166C and BDNF Val66Met polymorphisms contributed to vulnerability to lesion development in discrete tracts. The 3T structural MR images and blood samples for genetic analyses were acquired on 54 depressed and 37 nondepressed elders. Lesion maps were created through an automated tissue segmentation process and applied to a probabilistic white matter fiber tract atlas allowing for identification of the fraction of the tract occupied by lesion. The depressed cohort exhibited a significantly greater lesion ratio only in the left upper cingulum near the cingulate gyrus (F(1,86) = 4.62, P = 0.0344), supporting past work implicating cingulate dysfunction in the pathogenesis of depression. In the 62 Caucasian subjects with genetic data, AGTR1 C1166 carriers exhibited greater lesion ratios across multiple tracts including the anterior thalamic radiation and inferior fronto‐occipital fasciculus. In contrast, BDNF Met allele carriers exhibited greater lesion ratios only in the frontal corpus callosum. Although these findings did not survive correction for multiple comparisons, this study supports our hypothesis and provides preliminary evidence that genetic differences related to vascular disease may increase lesion vulnerability differentially across fiber tracts. Hum Brain Mapp, 2013. © 2011 Wiley Periodicals, Inc.
Tracheoesophageal puncture site closure with single perforator‐based deltopectoral flap
Authors: Balasubramanian Deepak , Iyer Subramania , Thankappan Krishnakumar 
Published: October 2011

AbstractBackgroundTracheoesophageal puncture (TEP) combined with a voice prosthesis is commonly used for voice production in postlaryngectomy patients. In certain cases, however, leakage occurs around the prosthesis. Many techniques have been described to correct this problem. Surgical closure of the puncture site has to be done if the conservative techniques fail. We present the use of the pedicled deltopectoral flap on the basis of a single perforator in the closure of these fistulae.MethodsThe reported technique was used in 6 patients over a period 8 years from 2004 to 2011.ResultsThe technique was successful in 5 patients. In 1 case there was dehiscence at the leading edge of the flap because of severe local wound infection.ConclusionThe novel technique described by us avoids the need for layered closure or dissection of the trachea and esophagus. It is simple and reliable and provides durable results. © 2011 Wiley Periodicals, Inc. Head Neck, 2013
Multi‐agent concurrent chemoradiotherapy for locally advanced head and neck squamous cell cancer in the elderly
Authors: Michal Stephanie A. , Adelstein David J. , Rybicki Lisa A. , Rodriguez Cristina P. , Saxton Jerrold P. , Wood Benjamin G. , Scharpf Joseph , Ives Denise I. 
Published: October 2011

AbstractBackgroundThe reported decreasing benefit with increasing age from concurrent chemoradiotherapy in head and neck cancer patients prompted this retrospective review.MethodsTwo courses of cisplatin‐based concurrent chemoradiotherapy were given to fit patients ≥70 years with locoregionally advanced cancers. Clinical characteristics, treatment, and outcomes were compared with those for an identically treated cohort <70 years.ResultsThere were 44 patients ≥70 and 137 patients <70 years. Clinical characteristics, treatment and toxicities were similar except that the elderly were less likely to receive both chemotherapy courses, experienced more myelosuppression, required more unplanned hospitalization, and were feeding‐tube dependent longer. Projected 5‐year disease‐specific survival (71% vs 74%) and freedom from recurrence (69% v. 71%) were nearly identical.ConclusionsAlthough these selected elderly patients experienced greater myelosuppression and supportive care requirements, outcomes were the same as in younger patients. Age alone should not be considered a contraindication to aggressive chemoradiotherapy for this disease. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
Infrahyoid flap reconstruction of oral cavity and oropharyngeal defects in elderly patients with severe general comorbidities
Authors: Deganello Alberto , Gitti Gianni , Parrinello Giampiero , Larotonda Guglielmo , Meccariello Giuseppe , Leemans C. René , Gallo Oreste 
Published: October 2011

AbstractBackgroundIn current practice, surgeons frequently deal with elderly patients who have severe medical comorbidities.MethodsWe present our series of 18 consecutive patients with severe general comorbidities that received infrahyoid flap reconstruction. The results were compared with those of 16 consecutive patients in good general medical state receiving free radial forearm flap reconstruction during the same study period. We also describe an original method for tongue base reconstruction using the infrahyoid flap.ResultsNo total flap necrosis was experienced; successful separation between oral cavity/oropharyngeal contents and neck spaces was obtained in all patients with a low rate of general complications. No significant differences were found with regard to verbal intelligibility and diet scores between groups.ConclusionsInfrahyoid flap in high‐risk cases represents a valid alternative to free radial forearm flap. We introduced a novel technical innovation for tongue base reconstruction using the infrahyoid flap with very encouraging results. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
Compressive stress–strain response of covalently crosslinked oxidized‐alginate/N‐succinyl‐chitosan hydrogels
Authors: Rogalsky Allan D. , Kwon H. J. , Lee‐Sullivan Pearl 
Published: October 2011

AbstractNovel injectable hydrogels have been formed at 37°C under physiological pH using a polymer–polymer crosslinking reaction. Three different formulations were tested. After 1‐day cure time at body temperature, the elastic modulus of unswollen samples ranged between 3 and 5 kPa but after 11 additional days at 4°C exceeded the target modulus of 10 kPa. Modulus data showed good agreement with theoretical crosslink density, enabling the prediction of stiffer/faster curing gel formulations. Rubber elasticity theory provided a good fit to the experimental data up to 73% compressive true strain. Based on an analysis of modulus results, it was inferred that despite the presence of two aldehyde functional groups, only one mechanically significant crosslink can form per oxidized repeat unit on the alginate chain. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A:, 2011.
Ultrastructure of spermatozoa in two solitary bee species with an emphasis on synapomorphic traits shared in the family apidae
Authors: Araújo Vinícius Albano , Serrão José Eduardo , Moreira Jane , Báo Sônia Nair , Lino‐neto José 
Published: October 2011

AbstractMorphology of spermatozoa in bees has provided promising results for phylogenetic analyses. In this work, the structure and ultrastructure of spermatozoa from Thygater (Thygater) analis and Melitoma segmentaria were characterized and the synapomorphies shared in the family Apidae are discussed. In these species, spermatozoa bundles which are undone in the seminal vesicle possess, on average, 50 cells. Spermatozoa consist of a head and a flagellar region. The head includes an acrosome containing the perforatorium, covered by the acrosomal vesicle and a nucleus. The flagellum is formed by two mitochondrial derivatives, which are asymmetric in diameter and length, with one centriolar adjunct, one axoneme (9 + 9 + 2), and two accessory bodies. In cross section the centriolar adjunct is asymmetric and the accessory bodies are triangular in shape. In the distal region of the flagellum, the derivative terminates before the axoneme and the small derivative terminates first. The axoneme is gradually disorganized and the accessories microtubules are the last to terminate. In these two species, spermatozoa share diverse synapomorphies with those of other bee species previously described in the literature, which allows for the establishment of a morphological pattern for spermatozoa of the family Apidae. Microsc. Res. Tech. 2012. © 2011 Wiley Periodicals, Inc.
Immunolocalization of S100‐like protein in the brain of an emerging model organism: Nothobranchius furzeri
Authors: D'Angelo Livia , De Girolamo Paolo , Cellerino Alessandro , Tozzini Eva Terzibasi , Varricchio Ettore , Castaldo Luciana , Lucini Carla 
Published: October 2011

AbstractThe S100 protein in nervous tissue appears to play important roles in regulating neuronal differentiation, glial proliferation, plasticity, development, axonal growth, and in neurogenetic processes. In fish, the adult neurogenic activity is much higher than in mammals. In this study, the localization of S100 protein was investigated in the brain of annual teleost fish, Nothobranchius furzeri, which is an emerging model organism for aging research. By immunohistochemical techniques, S100 immunoreactivity (IR) was detected in glial cells, small neurons, and fibers throughout all regions of central nervous system (CNS) with different pattern of distribution. In the telencephalon, S100 IR was seen in the olphactory bulbs and in different areas of the telencephalic hemispheres. In the diencephalon, S100 positivity was observed in the habenular nuclei of the epithalamus, in the cortical thalamic nucleus, in the dorsal, ventral and caudal portions, the latter with the posterior recessus nucleus, and in the diffuse inferior lobe of the hypothalamus, along the diencephalic ventricle and in the dorsal optic tract. In the mesencephalon, S100 IR was observed in the longitudinal tori, in the optic tectum, and along the mesencephalic ventricle. In the rhombencephalon, S100 IR was shown in valvula and body of the cerebellum, and in some nuclei of the medulla oblongata. The results suggest that S100 may play a key role in the maintenance of the CNS and in neurogenesis processes in the adulthood. © 2011 Wiley‐Liss, Inc.
Intracellular localization of samarium in the lactating mammary gland cells: Ultrastructural and microanalytical study
Authors: Ahlem Ayadi , Samira Maghraoui , Jean‐Nicolas Audinot , Mohamed‐Habib Jaafoura , Henri‐Noël Migeon , Ali El Hili , Leila Tekaya 
Published: October 2011

AbstractThe frequent use of some rare earths in the medical and industrial domains make us worry about their intracellular behavior into the body. Reason for which we have investigated the subcellular localization of one of these elements, the samarium, in the mammary gland of lactating female wistar rats using two very sensitive methods of observation and microanalysis, the transmission electron microscopy and the secondary ion mass spectrometry. The ultrastructural study showed the presence of electron dense deposits in the lactating mammary glandular epithelial cell lysosomes of the samarium‐treated rats, but no loaded lysosomes were observed in those of control rats. The microanalytical study allowed both the identification of the chemical species present in those deposits as samarium isotopes (152Sm+) and the cartography of its distribution. Our results confirm the previous ones showing that lysosomes of the glandular epithelial cells are the site of the intracellular concentration of foreign elements such as gallium. The intralysosomal deposits observed in the mammary glandular cells of the samarium‐treated rats are similar in their form and density to those observed with the same element in other varieties of cells, such as liver, bone marrow, and spleen cells. Our ultrastructural and microanalytical results and those obtained in previous studies allow deducing that the intralysosomal deposits are very probably composed of an insoluble samarium phosphate salt. © 2011 Wiley‐Liss, Inc.