bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Kualitas Produk Sari Roti Terhadap Keputusan Pembelian (Studi Pada Mahasiswa Administrasi Niaga Politeknik Negeri Jakarta)
Authors: Aini Nur , Susyanti Dewi Winarni , Azwar Azwar 
Published: May 2024

Pengaruh Kualitas Produk Sari Roti Terhadap Keputusan Pembelian studi pada mahasiswa Jurusan Administrasi Niaga, Politeknik Negeri Jakarta, 2017.Tujuan penelitian ini yaitu untuk menganalisis pengaruh variabel kualitas produk Sari Roti terhadap Keputusan Pembelian. Variabel Kualitas Produk memiliki lima indikator, yaitu Kinerja (Perfomance), Keistimewaan Tambahan (Features), Daya Tahan (Durability), Estetika (Esthetic), dan Citra dan Reputasi Produk (Perceived Quality). Sedangkan variable Keputusan Pembelian, yaitu Kemampuan pada suatu produk, Kebiasaan dalam membeli produk, Memberi Rekmendasi Kepada Orang Seseorang, dan Melalukan Pembelian Ulang. Penelitian ini memakai pendekatan kuantitatif dengan menggunakan teknik pengambilan sampel purposive sampling, yaitu teknik penentuan sampel dengan pertimbangan tertentu. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 88 responden. Hasil penelitian ini menunjukkan bahwa variabel kualitas produk Sari Roti berpengaruh positif Keputusan Pembelian pada mahasiswa Administrasi Niaga Politiknik Negeri Jakarta. Karena dalam penelitian ini 49,8% Keputusan Pembelian dapat dipengaruhi oleh kualitas produk Sari Roti. Sedangkan sisanya sebesar 51,8% dijelaskan oleh faktor-faktor lain diluar model yang dianalisis.
Ortaokul Matematik Dersi Öğretim Programının ve Ders Kitaplarının Bilgi ve İletişim Teknolojileri Kullanımına Yönlendirme Açısından İncelenmesi
Authors: Tural Sönmez Melike 
Published: May 2024

Bu çalışmanın amacı Türkiye’de kullanılan 2018 yılı ortaokul matematik dersi öğretim programının (OMDÖK) ve 2021 yılı Talim Terbiye tarafından beş yıl kullanılması onaylanmış olan ortaokul matematik ders kitaplarının (OMDK) Bilgi ve İletişim Teknolojilerine (BİT) yönlendirme açısından incelenmesidir. Araştırmada nitel araştırma yöntemlerinden doküman analizi kullanılmıştır. Analizin ilk aşamasında 2018 yılı OMDÖK’te yer alan kazanımlardan BİT kullanımına yönlendirmesine uygun olanlar tespit edilmiş ve tespit edilen bu kazanımlar sınıf seviyesine ve öğrenme alanlarına göre betimsel analize tabi tutulmuştur. Araştırmanın ikinci aşamasında ise OMDK’te yer alan BİT kullanımı içeren sorular, etkinlikler, problemler ve konu anlatımları OMDÖK’te belirlenen öğrenme alanına, alt öğrenme alanına ve kazanımlara göre betimsel, BİT araçlarının çeşidine ve kullanım amaçlarına göre de içerik analizine tabi tutulmuş; frekansları hesaplanmıştır. Yapılan incelemede 2018 yılı OMDÖK’de yer alan 21 kazanımda BİT yönlendirilmesi tespit edilmiş, bu yönlendirmelerin geometri ve ölçme, veri işleme ve cebir öğrenme alanlarında bulunduğu saptanmıştır. Ayrıca OMDK’ te yer alan BİT araçlarının kullanımının oldukça düşük olduğu (%1 ile %5 arasında) ve en çok sekizinci sınıf seviyesinde geometri ve ölçme alanlarında yer aldığı tespit edilmiştir. OMDK’te en çok yer alan BİT aracının matematik içerikli yazılımlar ve bilimsel hesap makineleri olduğu ve bu araçların bilgileri açıklamak, ardından kavram inşası ve alıştırma yapmak amacıyla kullanıldığı tespit edilmiştir.
Membangun Platform Digital Desa Margamulya Tanjung Kait Untuk Menuju Masyarakat Society 5.0
Authors: Hayat Cynthia , Marcel Marcel , Putro Endi , Windarto Yudhi , Perangin Angin Prasasti , Mudita Damida Shu , Setiawan Theodorous Stevanus , Christian Juan , Putratama Andhika , Christian Neil 
Published: May 2024

The village of Margamulya Tj. Kait is one of the foster villages of LPPM Ukrida. From the results of interviews and direct observations, there are several main issues faced by partners, including: limited access and dissemination of financial information and village profiles to external parties as well as to the villagers themselves. Community service is conducted by utilizing technology to develop a digital village community ecosystem where social media-based platforms serve as everyday communication, socialization, and collaboration tools. The implementation method is carried out through: (1) development of social media platforms; (2) training on platform usage. With the developed social media platform program, the target output is achieved through the evaluation of activities, where the benefit of interaction between village officials and villagers, as well as the dissemination and access to important information, becomes easier. Keywords: digital platform; village digitalization; digital village; margamulya village
PEMBERDAYAAN MASYARAKAT INDRALAYA RAYAMELALUI INTRODUKSI TEKNOLOGI SOLAR DRYING BIJI LOTUS (Nelumbo nucifera) LIAR
Authors: Ridhowati Sherly 
Published: May 2024

The use of natural water resources in the surrounding area must be utilized optimally through local source diversification activities, especially in Indralaya Raya village, Indralaya District, Ogan Ilir Regency. Availability of lotus seeds is abundant especially during rainy season but has not been utilized optimally. In services program, the introduction of solar drying technology was carried out through outreach and assistance to Village residents, especially youth organizations and micro small medium enterprises (UMKM), regarding the application of technology used for the drying process of lotus seeds, so that the dried lotus seeds could be stored longer for further used, then the next activity continued with the processing of diversified flour products and their derivatives. The success of this activity has shown that the Indralaya Raya residents were enthusiastic about this service activity as shown by the activity achievement indicators. Socialization and assistance activities on the use of solar-powered dryers and the manufacture of flour products and their derivatives have had a positive impact on the Indralaya Raya village community in empowering the activities of youth organizations and UMKMs.
The (Anarchic) Gift of Gelassenheit: On an Undeveloped Motif in Derrida's Donner le temps II
Authors: Moore Ian Alexander 
Published: May 2024

In his recently published Donner le temps II, Derrida raises, but does not develop, the possibility that Heidegger's notion of Gelassenheit (‘releasement’, ‘letting-be’) might escape the economic confines of exchange, debt, and repayment and therefore qualify as a pure gift. In this paper, I explore this possibility, explaining that Gelassenheit would have to be understood, first, not primarily as a human comportment but at the level of being itself, second, beyond appropriation, and third, as ‘without why’. If Heidegger's focus on appropriation in ‘Time and Being’ remains entangled in the economy of exchange (as Derrida insinuates in the final session of Donner le temps II), Heidegger's anarchic treatment of ‘letting’ ( laisser, Lassen) in the final session of his 1969 seminar in Le Thor opens instead onto a ‘pure giving’ ( pur donner, reines Geben).
Relationship between diagnosis of conus arteriosus malformation and genetic diagnosis results in fetal cardiac axis abnormalities by echocardiography during middle pregnancy
Authors: Yang Lin , Cai Yuting , Chen Huie , Ke Linfang , Wu Shufen 
Published: May 2024

ObjectiveTo explore the clinical value of echocardiography in detecting fetal cardiac axis abnormalities during middle pregnancy for diagnosing conus arteriosus malformation, and to compare and analyze the genetic diagnosis results, in order to provide evidence for clinical diagnosis and intervention.MethodsFour hundred twenty-one fetuses with conus arteriosus malformation from January 2020 to October 2023 were included as the conus arteriosus malformation group, and 917 healthy fetuses (all single fetuses) matched at the same gestational age were selected as the healthy group.ResultsThere was no significant difference in gestational weeks between two groups (P &gt; 0.05). The age of pregnant women in conus arteriosus malformation group was lower compared to healthy group (P &lt; 0.05), and the fetal cardiac axis in conus arteriosus malformation group was significantly higher compared to healthy group (P &lt; 0.05). Among the fetuses with conus arteriosus malformation, tetralogy of Fallot (TOF), transposition of the great arteries (TGA) and double outlet right ventricle (DORV) had the highest proportions, accounting for 38.00%, 18.29% and 17.58%, respectively. Among all types of conus arteriosus malformations, atresia pulmonary valve syndrome associated with TOF, persistent truncus arteriosus and DORV exhibited higher proportions of fetal cardiac axis abnormalities, at 75.00%, 36.84% and 27.03%, respectively, while TGA and interrupted aortic arch associated with B-type interruption had lower proportions of fetal cardiac axis abnormalities, at 2.60% and 4.55%, respectively. Genetic testing was conducted on 73 cases (17.34%) of fetuses with conus arteriosus malformation in this study. Among them, fetal cardiac axis abnormalities were considered positive for genetic results due to factors such as aneuploidy, copy number abnormalities, and single-gene pathogenicity. A total of 31 cases tested positive for genetic anomalies, with a positive rate of approximately 42.47%.ConclusionIn the middle pregnancy, the fetal cardiac axis in cases of conus arteriosus malformation was significantly higher than in normal fetuses. Moreover, there were variations in fetal cardiac axis among different types of conus arteriosus malformations, and these differences were notably associated with genetic diagnostic results.
Emotional experiences and gender roles of men with fibromyalgia syndrome: a cross-cultural qualitative study
Authors: Montesó-Curto Pilar , Toussaint Loren , Kueny Angela , Ruschak Ilga , Lunn Shannon , Rosselló Lluís , Campoy Carme , Clark Stephanie , Luedtke Connie , Gonçalves Alessandra Queiroga , Aguilar Martín Carina , Vincent Ann , Mohabbat Arya B. 
Published: May 2024

IntroductionGender roles may impact men with fibromyalgia, causing a high number of negative emotional states and affective disorders. There are few studies that detect men’s high emotional suffering. This study examined the emotional experience of men with fibromyalgia.MethodsA qualitative cross-cultural study utilized inductive thematic analysis was performed at the Fibromyalgia and Chronic Fatigue Unit Santa Maria University Hospital in Spain, the Fibromyalgia and Chronic Fatigue Clinic at Mayo Clinic in the US, and volunteers from the Winneshiek County in the US A total of 17 participants, 10 men from Spain and 7 men from the US were included.ResultsThree themes related to feelings/emotions emerged: (1) psychological level; (2) social level; and (3) physical level. Men with fibromyalgia from Spain and the US experienced many negative emotions. Men often experience negative emotions that are worsened by common misunderstandings and social biases/stigma about their condition.Conclusion/implications:A proper assessment of emotions when evaluating the global health of men with fibromyalgia as well as the provision of emotional support would improve their mental health and therefore their overall physical health. Emotional management should be incorporated into all treatment protocols for fibromyalgia, especially for men given the gender stigma. Health policies designed by legislators, policymakers, and support agencies must be accompanied by education in gender role concepts to improve the emotions of men with FMS. The mass media will be essential for the disclosure of the emotional suffering of male patients so that society might better understand them.
Construction of competing endogenous RNA networks in systemic lupus erythematosus by integrated analysis
Authors: He Juanjuan , Dai Yunfeng , Liu Jianwen , Lin He , Gao Fei , Chen Zhihan , Wu Yanfang 
Published: May 2024

ObjectiveSystemic lupus erythematosus (SLE) is a disease characterised by immune inflammation and damage to multiple organs. Recent investigations have linked competing endogenous RNAs (ceRNAs) to lupus. However, the exact mechanism through which the ceRNAs network affects SLE is still unclear. This study aims to investigate the regulatory functions of the ceRNAs network, which are important pathways that control the pathophysiological processes of SLE.MethodsCircRNA microarray for our tested assays were derived from bone marrow samples from three healthy individuals and three SLE patients in our hospital. The other sequencing data of circRNA, miRNA and mRNA were obtained from Gene Expression Omnibus (GEO) datasets. Using the limma package of R program, the differential expression of mRNA and miRNA in the GEO database was discovered. Then predicted miRNA-mRNA and circRNA-miRNA were established using miRMap, miRanda, miRDB, TargetScan, and miTarBase. CircRNA-miRNA-mRNA ceRNA network was constructed using Cytoscape, and hub genes were screened using a protein-protein interaction network. Immune infiltration analysis of the hub gene was also performed by CIBERSORT and GSEA.Results230 overlapped circRNAs, 86 DEmiRNAs and 2083 DEmRNAs were identified in SLE patients as compared to healthy controls. We constructed a circRNA–miRNA–mRNA ceRNAs network contained 11 overlapped circRNAs, 9 miRNAs and 51 mRNAs. ESR1 and SIRT1 were the most frequently associated protein-protein interactions in the PPI network. KEGG analysis showed that DEGs was enriched in FoxO signaling pathway as well as lipids and atherosclerosis. We constructed a novel circRNA-miRNA-mRNA ceRNA network (HSA circ 0000345- HSA miR-22-3-P-ESR1/SIRT1) that may have a major impact on SLE.ConclusionThrough this bioinformatics and integrated analysis, we suggest a regulatory role for ceRNA network in the pathogenesis and treatment of SLE.
Prediction of pedicled flap survival preoperatively by operating indocyanine green angiography at 1,450 nm wavelength: an animal model study
Authors: Shi Chenchen , Guo Linxiumei , Song Ruihu , Xu Heng , Zhang Yixin 
Published: May 2024

BackgroundPredicting flap viability benefits patients by reducing complications and guides flap design by reducing donor areas. Due to varying anatomy, obtaining individual vascular information preoperatively is fundamental for designing safe flaps. Although indocyanine green angiography (ICGA) is a conventional tool in intraoperative assessment and postoperative monitoring, it is rare in preoperative prediction.MethodsICGA was performed on 20 male BALB/c mice under five wavelengths (900/1,000/1,100, /1,250/1,450 nm) to assess vascular resolution after ICG perfusion. A “mirrored-L” flap model with three angiosomes was established on another 20 male BALB/c mice, randomly divided into two equal groups. In Group A, a midline between angiosomes II and III was used as a border. In Group B, the points of the minimized choke vessel caliber marked according to the ICG signal at 1,450 nm wavelength (ICG1450) were connected. Necrotic area calculations, pathohistological testing, and statistical analysis were performed.ResultsThe vascular structure was clearly observed at 1,450 nm wavelength, while the 900 to 1,100 nm failed to depict vessel morphology. Necrosis was beyond the borderline in 60% of Group A. Conversely, 100% of Group B had necrosis distal to the borderline. The number of choke vessels between angiosomes II and III was positively correlated with the necrotic area (%). The pathohistological findings supported the gross observation and analysis.ConclusionICG1450 can delineate the vessel structure in vivo and predict the viability of pedicled skin flaps using the choke vessel as the border between angiosomes.
An automated hybrid approach via deep learning and radiomics focused on the midbrain and substantia nigra to detect early-stage Parkinson’s disease
Authors: Chen Hongyi , Liu Xueling , Luo Xiao , Fu Junyan , Zhou Kun , Wang Na , Li Yuxin , Geng Daoying 
Published: May 2024

ObjectivesThe altered neuromelanin in substantia nigra pars compacta (SNpc) is a valuable biomarker in the detection of early-stage Parkinson’s disease (EPD). Diagnosis via visual inspection or single radiomics based method is challenging. Thus, we proposed a novel hybrid model that integrates radiomics and deep learning methodologies to automatically detect EPD based on neuromelanin-sensitive MRI, namely short-echo-time Magnitude (setMag) reconstructed from quantitative susceptibility mapping (QSM).MethodsIn our study, we collected QSM images including 73 EPD patients and 65 healthy controls, which were stratified into training-validation and independent test sets with an 8:2 ratio. Twenty-four participants from another center were included as the external validation set. Our framework began with the detection of the brainstem utilizing YOLO-v5. Subsequently, a modified LeNet was applied to obtain deep learning features. Meanwhile, 1781 radiomics features were extracted, and 10 features were retained after filtering. Finally, the classified models based on radiomics features, deep learning features, and the hybrid of both were established through machine learning algorithms, respectively. The performance was mainly evaluated using accuracy, net reclassification improvement (NRI), and integrated discrimination improvement (IDI). The saliency map was used to visualize the model.ResultsThe hybrid feature-based support vector machine (SVM) model showed the best performance, achieving ACC of 96.3 and 95.8% in the independent test set and external validation set, respectively. The model established by hybrid features outperformed the one radiomics feature-based (NRI: 0.245, IDI: 0.112). Furthermore, the saliency map showed that the bilateral “swallow tail” sign region was significant for classification.ConclusionThe integration of deep learning and radiomic features presents a potent strategy for the computer-aided diagnosis of EPD. This study not only validates the accuracy of our proposed model but also underscores its interpretability, evidenced by differential significance across various anatomical sites.
Hand, foot, and mouth disease: could EPs® 7630 be a treatment option? A prospective randomized open-label multicenter clinical study
Authors: Sütçü Murat , Kara Manolya , Yıldız Funda , Kılıç Ömer , Tural Kara Tugce , Akkoc Gulsen , Büyükçam Ayşe , Elmas Bozdemir Şefika , Özgür Gündeşlioğlu Özlem , Gül Doruk , İseri Nepesov Merve , Kara Ateş 
Published: May 2024

PurposeHand, foot and mouth disease (HFMD) is a viral contagious disease of children caused by human enteroviruses (EVs) and coxsackieviruses (CVs). There is no specific treatment option for HFMD. EPs® 7630's anti-infective and immunomodulatory properties have previously been demonstrated in several in vitro and in vivo studies; however, the use of this herbal medicine in children with HFMD has not previously been investigated.MethodsThis prospective randomized multicenter clinical study included 208 children with HFMD. The diagnosis was made by pediatricians. The patients who were within the first 48 h of symptom onset (according to the first onset of fever and skin findings) were enrolled. The study participants were assigned into 2 groups as EPs® 7630 and control groups. All patients were followed up twice more, 48 h after the first admission and on the 5th–7th day. Another phone evaluation was conducted for those with continued complaints from the previous visit.ResultsThe median age was 27 (12–112) months. The male-female ratio was 0.98. One hundred thirty one (63%) of 190 patients had no history of household contact. EPs® 7630 group included 94 and control group included 96 patients. A significant difference was found between the groups in terms of complaint scores at the visits made at the 48th h of the treatment and on days 5–7 (p &lt; 0.001). The mean ± SD disease duration of EPs® 7630 users was significantly shorter 6.07 ± 0.70 days (95% CI: 5.92–6.21)] than the control group [8.58 ± 0.94 days (95% CI: 8.39–8.77)] (p &lt; 0.001). Besides, the hospitalization rate among the EPs® 7630 users were significantly lower (p = 0.019). No side effects were observed, except for unpleasant taste, which was reported in 5 patients (EPs® 7630 group).ConclusionConsidering its efficacy and safety profile EPs® 7630 may represent a feasible herbal-based treatment option for children with HFMD.
Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT06353477).
Love beyond gluten: self-esteem, illness identity, and social support in romantic rejection concerns among adolescents with celiac disease
Authors: Shani Maor , van Zalk Maarten H. W. 
Published: May 2024

IntroductionFear of stigmatization, high perceived partner burden, or refraining from self-disclosure may manifest in romantic rejection concerns among adolescents with celiac disease (CD), potentially impacting their health-related quality of life (HRQOL). This study examined the prevalence, predictors, and consequences of romantic rejection concerns among adolescents and young adults with CD.MethodsA cross-sectional online survey was conducted among 165 German adolescents and young adults (aged 14–22) with self-reported CD. Participants completed measures of romantic rejection concerns, illness identity, self-esteem, peer support, and CD-specific HRQOL.ResultsParticipants reported moderate levels of concerns about the impact of CD on their romantic relationships, with no significant gender differences. Participants involved in romantic relationships expressed lower concerns of rejection, but similar preference for a “gluten-free partner.” Hierarchical regression analysis revealed that higher illness acceptance and peer support predicted lower rejection concerns. Significant interactions emerged between self-esteem and illness acceptance, and between self-esteem and peer support. Higher illness acceptance predicted fewer rejection worries only among those with high self-esteem, while peer support played a mitigating role only for those with low self-esteem. Romantic rejection concerns significantly predicted lower CD-specific HRQOL across all domains.DiscussionAnxieties about CD's impact on romantic relationships are prevalent among adolescents and may hinder their HRQOL. The findings highlight the complex interplay between self-esteem, illness identity, and social support in shaping romantic concerns. Targeted interventions focusing on peer support and fostering positive illness identity are recommended to alleviate rejection fears and improve HRQOL among youth with CD.