bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: β‐Carboline Alkaloids from the Leaves of Trigonostemon lii Y. T. Chang.
Authors: Li Shi‐Fei , Zhang Yu , Li Yan , Li Xin‐Rao , Kong Ling‐Mei , Tan Cheng‐Jian , Li Shun‐Lin , Di Ying‐Tong , He Hong‐Ping , Hao Xiao‐Jiang 
Published: July 2012

AbstractSix new β‐carboline alkaloids (I) and (II) are isolated and tested for their anticancer activity against five human cancer cell lines.
ChemInform Abstract: One‐Pot Sonogashira‐Cyclization Protocol to Obtain Substituted Furopyrimidine Nucleosides in Aqueous Conditions.
Authors: Fresneau Nathalie , Hiebel Marie‐Aude , Agrofoglio Luigi A. , Berteina‐Raboin Sabine 
Published: July 2012

AbstractUnder optimized conditions, the Sonogashira coupling of substrate (I) with alkynes is followed by cyclization.
ChemInform Abstract: Antiproliferative Activity Against Human Non‐Small Lung Cancer of Two O‐Alkyl‐diglycosylglycerols from the Marine Sponges Myrmekioderma dendyi and Trikentrion laeve.
Authors: Farokhi Fereshteh , Wielgosz‐Collin Gaetane , Robic Audrey , Debitus Cecile , Malleter Marine , Roussakis Christos , Kornprobst Jean‐Michel , Barnathan Gilles 
Published: July 2012

AbstractIdentification and biological activity of the new myrmekioside E (I) from the South Pacific marine sponge Myrmekioderma dendyi are reported.
ChemInform Abstract: Asymmetric Synthesis and Cytotoxicity of (‐)‐Saframycin A Analogues.
Authors: Dong Wenfang , Liu Wei , Yan Zheng , Liao Xiangwei , Guan Baohe , Wang Nan , Liu Zhanzhu 
Published: July 2012

AbstractA series of (‐)‐saframycin A analogues (I) are prepared from L‐tyrosine in 24 steps and evaluated for their in vitro cytotoxicity against a panel of ten human tumor cell lines.
ChemInform Abstract: Growth of p‐Type Hematite by Atomic Layer Deposition and Its Utilization for Improved Solar Water Splitting.
Authors: Lin Yongjing , Xu Yang , Mayer Matthew T. , Simpson Zachary I. , McMahon Gregory , Zhou Sa , Wang Dunwei 
Published: July 2012

AbstractMg‐doped α‐Fe2O3 is synthesized by atomic layer deposition at 180 °C using Fe2(O‐tBu)6, water, and bis(ethylcyclopentadienyl)magnesium as Fe, O, and Mg precursors, respectively.
ChemInform Abstract: N‐Acylpyrroles: More Than Amides.
Authors: Goldys Anna M. , McErlean Christopher S. P. 
Published: July 2012

AbstractReview: preparation, electronic properties, and synthetic applications as acylating agents, enhancing the reactivity of α,β‐unsaturated systems, formation of enolates and silyl enol ethers, Diels—Alder‐type chemistry on the pyrrole ring; 103 refs.
ChemInform Abstract: 2‐Chloroquinoline‐3‐carbaldehydes: Synthesis, Reactions and Applications
Authors: Abdel‐Wahab Bakr F. , Khidre Rizk E. , Farahat Abdelbasset A. , El‐Ahl Abdel‐Aziz Sayed 
Published: July 2012

AbstractReview: 183 refs.
The Impact of Preoperative Imaging for Atypical Atrial Myxoma Locations
Authors: Edwdard Hatz Daniel , Danielson Daren , Nilas Young J. , Amsterdam Ezra 
Published: July 2012

AbstractBackground:Atrial myxomas are the most common primary cardiac neoplasm. The majority (75%–80%) are located in the left atrium at the base of the foramen ovalis. Surgical removal can prevent dangerous obstructive or thromboembolic sequelae.Hypothesis:Atypically located tumors may present technical challenges requiring case‐specific surgical adaptations when visualization or surrounding cardiac structures are compromised.Methods:We describe 3 cases of atypically located atrial myxomas that required preoperative transesophageal echocardiography and computed tomography to afford the optimal surgical approach.Conclusions:These cases highlight the potential need for multimodality imaging of atypically located atrial myxomas to determine the optimal technical approach for excision. Clin. Cardiol. 2012 doi: 10.1002/clc.22027The authors have no funding, financial relationships, or conflicts of interest to disclose.
B‐type Natriuretic Peptides in Acute Coronary Syndromes: Implications in an Aging Population
Authors: Krim Selim R. , Vivo Rey P. , de Lemos James A. 
Published: July 2012

AbstractB‐type natriuretic peptide (BNP) and N‐terminal‐proBNP (NT‐proBNP) are increasingly recognized as prognostic markers in patients with acute coronary syndrome (ACS). The need for novel and more effective tools for risk assessment cannot be more emphasized than in older patients with ACS given their atypical presentation, multiple comorbidities, and higher risk for mortality and morbidity. Accurate interpretation of B‐type NP values in older patients with ACS, however, may be confounded by several aging‐related physiologic changes. Advanced age, reduction in body mass, and kidney function and anemia have been associated with higher BNP and NT‐proBNP concentrations, and may create challenges with interpreting NP levels in the elderly. This review highlights the need to better understand the physiology of BNP and NT‐proBNP in older individuals and their prognostic value in older patients with ACS. Clin. Cardiol. 2012 doi: 10.1002/clc.22035Dr. de Lemos has received grant support from Roche Diagnostics and Abbott Diagnostics. The authors have no other funding, financial relationships, or conflicts of interest to disclose.
Designing Iron‐Amended Biosand Filters for Decentralized Safe Drinking Water Provision
Authors: Noubactep Chicgoua , Temgoua Emile , Rahman Mohammad A. 
Published: July 2012

AbstractThere are ongoing efforts to render conventional biosand filters (BSF) more efficient for safe drinking water provision. One promising option is to amend BSF with a reactive layer containing metallic iron (Fe0). The present communication presents some conceptual options for efficient Fe0‐amended BSF in its fourth generation. It is shown that a second fine‐sand layer should be placed downwards from the Fe0‐reactive layer to capture dissolved iron. This second fine‐sand layer could advantageously contain adsorbing materials (e.g. activated carbons, wooden charcoals). An approach for sizing the Fe0‐reactive layer is suggested based on 3 kg Fe0 per filter. Working with the same Fe0 load will ease comparison of results with different materials and the scaling up of household BSF to large scale community slow sand filters (SSF).
Investigation of the Possibility of Copper Removal from Industrial Leachate by Raw and Calcined Phosphogypsum: D‐Optimal and Taguchi Designs
Authors: Mesci Başak , Turan Nurdan Gamze , Ozgonenel Okan 
Published: July 2012

AbstractIn the present study, the removal of Cu(II) was evaluated by raw and calcined phosphogypsum (PG) as an industrial product. The role of experimental factors on the removal of Cu(II) was examined by using D‐optimal and Taguchi designs. The experimental factors and their related levels were selected as initial pH of 3–6–8, adsorbent content of 5, 10, and 25 g L−1, contact time of 5, 10, and 20 min, and temperature of 20, 40, and 60°C. The results are evaluated by ANOVA test to extract important experimental factors and their levels. The performances of the suggested factorial designs were then compared and regression models that took into account the significant main and interaction effects were suggested. Taguchi design was found as a reliable solution with less number of experiments for adsorption studies with the optimized values. The resultant removal efficiency is calculated as 78.34%. The results revealed that calcined PG is an appropriate adsorbent for Cu(II) removal from leachate of industrial waste.
Aggregation and Solvation of Chiral N,P‐Amide Ligands in Coordinating Solvents: A Computational and NMR Spectroscopic Study
Authors: Rönnholm Petra , Nilsson Lill Sten O. , Gräfenstein Jürgen , Norrby Per‐Ola , Pettersson Mariell , Hilmersson Göran 
Published: July 2012

AbstractThe lithium amides of a series of chiral N,P ligands were studied in solution. This ligand class had been shown previously to give good selectivities in asymmetric alkylation of benzaldehyde. These lithium amides were found to aggregate into dimers with surprisingly strong coordination of phosphorus to lithium. The equilibrium between dimeric forms was found to depend strongly on non‐bonded interactions within the solute and between solute and solvent. Only if dispersion and free‐energy contributions were scaled to approximately 20 % of the gas‐phase values was it possible to reproduce the experimentally observed aggregation preferences. NMR spectroscopic shieldings were calculated and found to correlate well with the experimentally observed shifts. Calculated Li,P couplings were shown to be a sensitive measure of the LiP distance.
Distillate‐Range Products from Non‐Oil‐Based Sources by Catalytic Cascade Reactions
Authors: Lacarriere Antoine , Robin Julien , Świerczyński Dariusz , Finiels Annie , Fajula François , Luck Francis , Hulea Vasile 
Published: July 2012

AbstractAn original two‐step process efficiently catalyzed by functionalized mesoporous materials is proposed as a potential route for converting light olefins into long‐chain hydrocarbons in the distillate range. In the first step, ethylene can be selectively transformed into C4–C10 olefins with an even number of carbon atoms, over nickel‐exchanged AlMCM‐41, at 150 °C. When the nickel‐catalyzed oligomerization was assisted by a second acid‐catalyzed step over H‐MCM‐41, olefins with chains longer than 10 carbon atoms were mainly produced with a productivity of 180 g g−1 h−1.
Resource allocation scheme for orthogonal frequency division multiple access networks based on cooperative game theory
Authors: Alavi Seyed Mohamad , Zhou Chi 
Published: July 2012

SUMMARYCooperative game theory can be applied to orthogonal frequency division multiple access (OFDMA) networks for fair resource allocation. In this work, we consider a comprehensive cross‐layer framework including physical and medium access control layer requirements. We apply two cooperative games, nontransferable utility (NTU) game and transferable utility (TU) game, to provide fairness in OFDMA networks. In NTU game, fairness is achieved by defining appropriate objective function, whereas in TU game, fairness is provided by forming the appropriate network structure. For NTU game, we analyze the Nash bargaining solution as a solution of NTU game taking into account channel state information and queue state information. In a TU game, we show that coalition among subcarriers to jointly provide rate requirements leads to better performance in terms of power consumption. The subcarrier's payoff is determined according to the amount of payoff which that subcarrier brings to the coalition by its participation. We show that although NTU and TU games are modeled as rate adaptive and margin adaptive problems, respectively, both solutions provide a fair distribution of resources with minimum fairness index of 0.8. Copyright © 2012 John Wiley & Sons, Ltd.
Social Learning Through Environmental Risk Analysis of Biodiversity and GM Maize in South Africa
Authors: Dana Genya V. , Nelson Kristen C. 
Published: July 2012

ABSTRACTEnvironmental risk analyses (ERAs) can benefit from participatory methods that enhance social learning, whereby diverse participants share knowledge and perspectives to learn about complex socio‐ecological systems, develop a collective understanding of the risk problem and build support for specific solutions. We used surveys and interviews to investigate social learning among 22 stakeholders during a participatory ERA workshop to evaluate risks of genetically modified maize to South African biodiversity. The ERA process incorporated methodologies designed to enhance social learning, such as open communication, constructive conflict and extended engagement. We observed that social learning occurred as participants understood new information and perspectives, began thinking systemically and transformed their impressions of other participants. In this workshop, they did not develop a shared understanding of the ERA process or priority risks. However, the ERA workshop did engender social learning about other stakeholders, socio‐ecological systems and risk, creating a foundation for longer, iterative engagement needed to build shared understanding of complex problems and solutions related to biodiversity governance. Copyright © 2012 John Wiley & Sons, Ltd and ERP Environment
Preparation of Hollow TiO2 Spheres of the Desired Polymorphs by Layer‐by‐Layer Assembly of a Water‐Soluble Titanium Complex and Hydrothermal Treatment (Eur. J. Inorg. Chem. 20/2012)
Authors: Katagiri Kiyofumi , Inami Hitoshi , Koumoto Kunihito , Inumaru Kei , Tomita Koji , Kobayashi Makoto , Kakihana Masato 
Published: July 2012

AbstractThe cover picture shows the formation process of brookite‐type TiO2 hollow spheres through layer‐by‐layer assembly and hydrothermal treatment. The core–shell particles were formed by alternate deposition of the titanium–glycolate complex and positively charged polyelectrolyte on spherical polystyrene spheres utilizing electrostatic interactions. Hollow spheres formed with the polyionic titanium–glycolate complex and the cationic polyelectrolyte were obtained by removal of the polystyrene templates. The hollow shell was successfully crystallized as brookite‐type TiO2 by a hydrothermal treatment at pH = 4. Details are discussed in the article by K. Katagiri et al. on p. 3267 ff. magnified image
Transition‐Metal‐Catalyzed Cyclization of Alkynals via Oxametallacycle Intermediates (Eur. J. Org. Chem. 20/2012)
Authors: Tanaka Ken , Tajima Yuki 
Published: July 2012

AbstractThe cover picture shows the Japanese famous inverted image of Mt. Fuji (reflected in the water). The scheme shows the general catalytic cycle of the transition‐metal‐catalyzed cyclization of alkynals via oxametallacycle intermediates. This cyclization is a highly efficient method for the stereoselective synthesis of carbocycles and heterocycles. This reaction is catalyzed by Ni, Rh, Ru, and Ti complexes and mediated by organometalloid reagents (X–Y = Si–H, B–C), organometallic reagents (X–Y = Zn–C), dihydrogen (X–Y = H–H), and organic reagents (X–Y = C–H, C–P). Details are presented in the Microreview by K. Tanaka and Y. Tajima on p. 3715 ff. magnified image
From mass‐wasting to slope stabilization – putting constrains on a tectonically induced transition in slope erosion mode: a case study in the Judea Hills, Israel
Authors: Ryb Uri , Matmon Ari , Porat Naomi , Katz Oded 
Published: July 2012

ABSTRACTCalcrete‐coated remnants of landslide debris and alluvial deposits are exposed along the presently stable hillslopes of the Soreq drainage, Judea Hills, Israel. These remnants indicate that a transition from landslide‐dominated terrain to dissolution‐controlled hillslope erosion had occurred. This transition possibly occurred due to the significant decrease in tectonic uplift during the late Cenozoic. The study area is characterized by sub‐humid Mediterranean climate. The drainage hillslopes are typically mantled by thick calcrete crusts overlying Upper Cretaceous marine carbonate rocks. Using TT‐OSL dating of aeolian quartz grains incorporated in the calcrete which cements an ancient landslide deposit, we conclude that incision of ~100 m occurred from 1056 ± 262 to 688 ± 86 ka due to ~0·3° westward tilt of the region; such incision invoked high frequency of landslide activity in the drainage. The ages of a younger landslide remnant, alluvial terrace, and alluvial fan, all situated only a few meters above the present level of the active streambed, range between 688 ± 86 ka and 244 ± 25 ka and indicate that since 688 ± 86 the Soreq base level had stabilized and that landslide activity decreased significantly by the middle Pleistocene. Copyright © 2012 John Wiley & Sons, Ltd.
River flux uncertainties predicted by hydrological variability and riverine material behaviour
Authors: Moatar Florentina , Meybeck Michel , Raymond Sébastien , Birgand François , Curie Florence 
Published: July 2012

AbstractData on riverine fluxes are essential for calculating element cycles (carbon, nutrients, pollutants) and erosion rates from regional to global scales. At most water‐quality stations throughout the world, riverine fluxes are calculated from continuous flow data (q) and discrete concentration data (C), the latter being the main cause of sometimes large uncertainties. This article offers a comprehensive approach for predicting the magnitude of these uncertainties for water‐quality stations in medium to large basins (drainage basin area > 1000 km²) based on the commonly used discharge‐weighted method. Uncertainty levels – biases and imprecisions – for sampling intervals of 3 to 60 days are correlated first through a nomograph with a flux variability indicator, the quantity of riverine material discharged in 2% of time (M2%). In turn, M2% is estimated from the combination of a hydrological reactivity index, W2% (the cumulative flow volume discharged during the upper 2% of highest daily flow) and the truncated b50sup exponent, quantifying the concentration versus discharge relationship for the upper half of flow values (C = a q b50sup, for q > q50, where q50 is the median flow): M2% = W2% + 27.6b50sup. W2% can be calculated from continuous flow measurements, and the b50sup indicator can be calculated from infrequent sampling, which makes it possible to predict a priori the level of uncertainty at any station, for any type of riverine material either concentrated (b50sup > 0) or diluted (b50sup > 0) with flow. A large data base of daily surveys, 125 station variables of suspended particulate matter (SPM), total dissolved solids (TDS) and dissolved and particulate nutrients, was used to determine uncertainties from simulated discrete surveys and to establish relationships between indicators. Results show, for example, that for the same relatively reactive basin (W2% > 25%), calculated fluxes from monthly sampling would yield uncertainties approaching ±100% for SPM (b50sup > 1.4) fluxes and ±10% for TDS (b50sup = −0.2). The application to the nitrate survey of the river Seine shows significant trends for the 1972–2009 records. Copyright © 2012 John Wiley & Sons, Ltd.
Erosion source discrimination in a rural Australian catchment using compound‐specific isotope analysis (CSIA)
Authors: Hancock Gary J. , Revill Andrew T. 
Published: July 2012

AbstractCompound‐specific isotope analysis (CSIA) has been used to assess the ability of δ13C signatures of fatty acid compounds to discriminate erosion sources in a rural Australian catchment. The study focussed on a high flow event (10‐year recurrence interval) which occurred in the Logan–Albert catchment in January 2008, and augmented a previous sediment tracing study using fallout radionuclides and major/minor element geochemistry. It is found that surface soil from forest, pasture and cultivated land uses are well discriminated using CSIA. Furthermore, sub‐surface soil sources associated with channel bank erosion and exposed subsoils (gullies and hillslope scalds) occurring specifically in the mid‐western Logan catchment could also be discriminated. Selected fatty acid and bulk carbon δ13C data were used in the IsoSource mixing model to determine erosion sources contributing sediment. The results were compared with results obtained using other sediment tracers. For the lower Logan River, the CSIA tracing results are consistent with fallout radionuclide and element geochemistry tracing, with channel bank erosion being confirmed as the major sediment source. Moreover, CSIA has quantified the significant contribution of exposed subsoils originating on hillslopes and drainage lines from the mid‐western region of the Logan catchment. In the Albert River catchment, about 40% of sediment comes from forest land use, although more than half of this may come from sub‐surface sources. These results have demonstrated that CSIA has the potential to significantly enhance the ability of sediment tracing studies to determine the extent that different land uses and erosion processes are contributing eroded soil to rivers, allowing an assessment of soil erosion and transport model predictions. Copyright © 2012 John Wiley & Sons, Ltd.
Global estimates of cancer prevalence for 27 sites in the adult population in 2008
Authors: Bray Freddie , Ren Jian‐Song , Masuyer Eric , Ferlay Jacques 
Published: July 2012

AbstractRecent estimates of global cancer incidence and survival were used to update previous figures of limited duration prevalence to the year 2008. The number of patients with cancer diagnosed between 2004 and 2008 who were still alive at the end of 2008 in the adult population is described by world region, country and the human development index. The 5‐year global cancer prevalence is estimated to be 28.8 million in 2008. Close to half of the prevalence burden is in areas of very high human development that comprise only one‐sixth of the world's population. Breast cancer continues to be the most prevalent cancer in the vast majority of countries globally; cervix cancer is the most prevalent cancer in much of Sub‐Saharan Africa and Southern Asia and prostate cancer dominates in North America, Oceania and Northern and Western Europe. Stomach cancer is the most prevalent cancer in Eastern Asia (including China); oral cancer ranks as the most prevalent cancer in Indian men and Kaposi sarcoma has the highest 5‐year prevalence among men in 11 countries in Sub‐Saharan Africa. The methods used to estimate point prevalence appears to give reasonable results at the global level. The figures highlight the need for long‐term care targeted at managing patients with certain very frequently diagnosed cancer forms. To be of greater relevance to cancer planning, the estimation of other time‐based measures of global prevalence is warranted.
In vivo bioluminescent imaging of α‐fetoprotein‐producing hepatocellular carcinoma in the diethylnitrosamine‐treated mouse using recombinant adenoviral vector
Authors: Kim Kwang Il , Park Ju Hui , Lee Yong Jin , Lee Tae Sup , Park Jae Jun , Song Inho , Nahm Sang‐Soep , Cheon Gi Jeong , Lim Sang Moo , Chung June‐Key , Kang Joo Hyun 
Published: July 2012

AbstractBackgroundThe in vivo molecular imaging method is a useful tool for monitoring carcinogenesis in various hepatocellular carcinoma (HCC) models, such as xenografted‐, chemical induced‐ and transgenic mice. The tumor‐specific gene expression strategy, such as transcriptional targeting, is essential for achieving a lower toxicity for normal liver tissue in therapy and the monitoring of tumor progression in diagnosis, respectively. The present study aimed to visualize spontaneously developing α‐fetoprotein (AFP)‐producing HCC through targeted gene expression in tumors using recombinant adenoviral vector.MethodsThe recombinant adenovirus vector, AdAFPfLuc (containing firefly luciferase gene driven by human AFP enhancer/promoter) was prepared. After in vitro infection by adenovirus, gene expression was confirmed using the luciferase assay, semi‐quantitative reverse transcriptase‐polymerase chain reaction and western blotting in AFP‐producing and nonproducing cells. Tumor‐bearing mice were intravenously injected with adenovirus, and bioluminescent images were obtained.ResultsThe expression of fLuc was efficiently demonstrated by the luciferase assay in AFP‐producing cells but not in AFP‐nonproducing cells. AFP‐producing HCC targeted gene expression was confirmed at the mRNA and protein levels. After being injected intravenously in HuH‐7 xenografts and HCC‐bearing diethylnitrosamine‐treated mice using adenovirus, functional reporter gene expression was confirmed in tumors by in vivo bioluminescent imaging (BLI).ConclusionsThe recombinant adenovirus vector system can be used to monitor spontaneously developing AFP‐producing HCC and to evaluate targeted gene expression in tumors by in vivo BLI in a small animal model. Copyright © 2012 John Wiley & Sons, Ltd.