bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on poly(butylene adipate‐co‐terephthalate)/thermoplastic starch/poly((R)‐3‐hydroxybutyrate‐co‐(R)‐3‐hydroxyhexanoate) biodegradable films with enhanced gas barrier properties
Authors: Wang Zepeng , Tian Hanlin , Yu Jinshuo , Zheng Gaofei , Zhao Yan , Yan Xiangyu , Bian Junjia , Pan Hongwei , Zhang Huiliang , Tan Zhiyong 
Published: June 2024

AbstractBioplastic films with excellent barrier properties were successfully prepared from poly(butylene adipate‐co‐terephthalate) (PBAT), thermoplastic starch (TPS), and poly((R)‐3‐hydroxybutyrate‐co‐(R)‐3‐hydroxyhexanoate) (PHBHHx). The rheological, mechanical, barrier, dynamic mechanical properties, and microstructure of the PBAT/TPS/PHBHHx films were studied. The transition of the continuous phase in the blend significantly affects the properties of the films. The increase in PHBHHx content results in its transition from a dispersed phase to a continuous phase. This phase transition, along with the consequent increase in the crystallinity of PHBHHx, greatly enhances the barrier properties of the film. The percentage crystalline degree of PHBHHx increased from 10.9% to 25.1% with increasing PHBHHx content from 0% to 50%. The film containing 50% PHBHHx showed a significant decrease in both water vapor permeability (WVP) and oxygen permeability (OP) by 75.1% and 69.6%, respectively. It found that the film containing 50% PHBHHx exhibited a decrease of elongation at break from 505% to less than 10% but an unusual increase of tensile strength after a 72‐hour aging test, which is different from PBAT and PBAT/TPS films. However, this indicates that the extensibility of PHBHHx is more susceptible to the effects of aging test, leading to the rearrangement of polymer chains from disordered to ordered morphology.
Marine algae‐derived characterized bioactive compounds as therapy for cancer: A review on their classification, mechanism of action, and future perspectives
Authors: Liao Wei , Chen Yaobin , Shan Shuo , Chen Zhengxin , Wen Yuxi , Chen Weichao , Zhao Chao 
Published: June 2024

AbstractIn 2022, there were around 20 million new cases and over 9.7 million cancer‐related deaths worldwide. An increasing number of metabolites with anticancer activity in algae had been isolated and identified, which were promising candidates for cancer therapy. Red algae are well‐known for the production of brominated metabolites, including terpenoids and phenols, which have the capacity to induce cell toxicity. Some non‐toxic biological macromolecules, including polysaccharides, are distinct secondary metabolites found in many algae, particularly green algae. They possess anticancer activities by inhibiting tumor angiogenesis, stimulating the immune response, and inducing apoptosis. However, the structure–activity relationship between these components and antitumor activity, as well as certain taxa within the algae, remains relatively unstudied. This work is based on the reports published from 2003 to 2024 in PubMed and ISI Web of Science databases. A comprehensive review of the characterized algal anticancer active compounds, together with their structure and mechanism of action was performed. Also, their structure–activity relationship was preliminarily summarized to better assess their potential properties as a natural, safe bioactive product to be used as an alternative for the treatment of cancers, leading to new opportunities for drug discovery.
Effect of serum anti‐Müllerian hormone levels on the superovulation response in Holstein heifers
Authors: Yildiz Mehmet , Bastan Ilktan , Guler Sohret , Cetin Yunus 
Published: June 2024

AbstractBackgroundAnti‐Müllerian hormone (AMH) holds potential as a biomarker for assessing the superovulation (SO) response in cattle. Nonetheless, there exists scant information regarding this aspect in the literature concerning dairy heifers. Given this gap, our objective is to explore the viability of AMH as an indicator for gauging the SO response specifically in Holstein heifers. Furthermore, our aim encompasses examining the variations in AMH levels within the same individuals before and after undergoing SO.MethodsThe study included 41 Holstein heifers. All heifers were superovulated and blood samples were taken both before and after the SO protocol.ResultsThe findings revealed that the mean values of serum AMH concentrations before and after SO were 0.122 ng/mL (0.093–0.248 ng/mL) and 0.119 ng/mL (0.084–0.170 ng/mL), respectively. AMH concentrations in heifers were stratified into low (<0.106 ng/mL), medium (0.107–0.126 ng/mL) and high (>0.127 ng/mL) categories both before and after SO.ConclusionsThere was no significant correlation between AMH levels in the heifers both before and after SO treatment with the number of follicles, corpora lutea, total embryos collected or embryos transferred (p > 0.05). Furthermore, this study showed that serum AMH concentrations in Holstein heifers did not change after SO treatment. In this study, as AMH levels in Holstein heifers were in a narrow range, a relationship between AMH and SO response could not be determined. In future studies, we believe that it would be more useful to plan more studies in Holstein donor heifers, taking into account the number of animals and AMH levels.
Laparoscopic dissection of the first and second porta hepatis along Laennec's capsule via “Hepatic Serosal Incision” approach: How I do it
Authors: Zhang Chuanhai , Ma Jinliang , Zhou Yi 
Published: June 2024

AbstractTo provide a standardized approach for laparoscopic access to dissection of the first and second porta hepatis. By opening a portion of the hepatic serosa and subsequently exposing the hepatic Laennec's capsule, dissection of the first and second porta hepatis was performed along the Laennec's capsule. Utilizing the “Hepatic Serosal Incision” approach along the Laennec's capsule enabled the precise dissection of the left and right hepatic pedicles of the first porta hepatis and the root of the hepatic veins at the second porta hepatis under laparoscopy. This method allows for rapid and accurate access to the space between Laennec's capsule and the hepatic hilar plate system under laparoscopy as well as clear exposure of the root of the hepatic veins and their branches, facilitating more precise laparoscopic anatomical liver resection.
Driver Distraction Detection Using Artificial Intelligence and Smart Devices
Authors: Papatheocharous Efi , Buffoni David , Maurer Matthias , Wallberg Anders , Ezquerro Gonzalo 
Published: June 2024

AbstractDistracted driving is known to be one of the leading causes of vehicle accidents. With the increase in the number of sensors available within vehicles, there exists an abundance of data for monitoring driver behaviour, which, however, has so far only been comparable across vehicle manufacturers to a limited extent due to proprietary solutions. A special role in distraction is played by smart devices, usually used while driving, such as smartphones and smartwatches. They are repeatedly a source of distraction for drivers through calls, messages, notifications and apps usage. However, such devices can also be used for driver behaviour monitoring (like driver distraction detection), as current developments show. As vehicle manufacturer-independent devices, which are usually equipped with adequate sensor technology, they can provide significant advantages and opportunities. This work illustrates the opportunities in using smartphones and wearables to detect driver distraction. The overall architecture description of the concept, called Smart Devices Distracted Driving Detection, is presented together with a series of initial experiments of a proof-of-concept. Artificial Intelligence and more especially Machine Learning is used to assess driving distractions using smart devices in a comprehensive manner.
Semi-automated software improves interrater reliability and reduces processing time of magnetic resonance imaging-based exocrine pancreatic assessments in pediatric patients
Authors: Dudley Jonathan A. , Ata Nadeen Abu , Murdock Kyle E. , Vitale David S. , Abu-El-Haija Maisam , Trout Andrew T. 
Published: June 2024

Abstract
Objectives
Magnetic resonance (MR) imaging with secretin stimulation (MR-PFTs) is a non-invasive test for pancreatic exocrine function based on assessing the volume of secreted bowel fluid in vivo. Adoption of this methodology in clinical care and research is largely limited to qualitative assessment of secretion as current methods for secretory response quantification require manual thresholding and segmentation of MR images, which can be time-consuming and prone to interrater variability. We describe novel software (PFTquant) that preprocesses and thresholds MR images, performs heuristic detection of non-bowel fluid objects, and provides the user with intuitive semi-automated tools to segment and quantify bowel fluid in a fast and robust manner. We evaluate the performance of this software on a retrospective set of clinical MRIs.

Methods
Twenty MRIs performed in children (< 18 years) were processed independently by two observers using a manual technique and using PFTquant. Interrater agreement in measured secreted fluid volume was compared using intraclass correlation coefficients, Bland-Altman difference analysis, and Dice similarity coefficients.

Results
Interrater reliability of measured bowel fluid secretion using PFTquant was 0.90 (0.76–0.96 95% C.I.) with − 4.5 mL mean difference (-39.4–30.4 mL 95% limits of agreement) compared to 0.69 (0.36–0.86 95% C.I.) with − 0.9 mL mean difference (-77.3–75.5 mL 95% limits of agreement) for manual processing. Dice similarity coefficients were better using PFTquant (0.88 +/- 0.06) compared to manual processing (0.85 +/- 0.10) but not significantly (p = 0.11). Time to process was significantly (p < 0.001) faster using PFTquant (412 +/- 177 s) compared to manual processing (645 +/- 305 s).

Conclusion
Novel software provides fast, reliable quantification of secreted fluid volume in children undergoing MR-PFTs. Use of the novel software could facilitate wider adoption of quantitative MR-PFTs in clinical care and research.
Crossed-reflex in antiphospholipid chorea
Authors: Fernández-Vidal Joan Miquel , Olmedo-Saura Gonzalo , Querol-Gutiérrez Luis Antonio , Kulisevsky Jaime , Pérez-Pérez Jesús 
Published: June 2024

AbstractChorea is a hyperkinetic movement disorder associated with various underlyingconditions, including autoimmune diseases such as antiphospholipid syndrome (APS). APS can manifest with a wide range of neurological symptoms, including chorea. We present a case of a 77-year-old man with subacute generalized chorea secondary to primary APS. Notably, the patient exhibited a left patellar crossed-reflex, a phenomenon rarely documented in chorea cases, the pathophysiology of which has not yet been elucidated. In summary, this case challenges the traditional demographics of antiphospholipid syndrome (APS) by suggesting a potential link between APS and late-age patients. It emphasizes the importance of considering APS in late-onset chorea cases.
Dialogue on ethics and ethics of dialogue: an exploratory study
Authors: Brandel Noa , Schwarz Baruch B. , Cedar Talli , Baker Michael J. , Bietti Lucas M. , Pallarès Gwen , Détienne Françoise 
Published: June 2024

AbstractWe report on a study bearing implications for ethical learning in schoolchildren during social interaction. The study was conducted as part of a project aimed at promoting ethical learning of socially-oriented values within the context of dialogic education. 172 fourth graders from 7 classes participated in an 8-session series designed to foster empathy, inclusion, and tolerance. Two of these sessions (3 and 8) were pre-selected for analysis. We investigated (1) whether students’ discussion of ethical issues and the ethical aspects of their actual in-class interaction with each other can be reliably measured, and (2) what relation holds between students’ ethical thinking during classroom discussions and the ethical aspects of their behavior. We thus developed an analytical framework comprising two tools for appraising ethical thinking and behavior in in-class interaction: dialogue on ethics (DoE) and ethics of dialogue (EoD). This framework was applied to the dialogues taken from the two sessions. The DoE and EoD tools proved reliable, as inter-rater agreement was substantial. Moreover, the relation between children’s DoE and their EoD was positive where the topic posed for discussion presented a dilemma and students’ interaction proceeded under moderate teacher guidance. In contrast, it was negative when the discussion was conceptual, and the teacher was dominant. We conclude that (1) DoE/EoD is a suitable framework for studying children’s ethical learning and development in social interaction, and (2) ethical learning, in its epistemological and behavioral dimensions, can be boosted or inhibited in a context of dialogic education, depending on design principles.
Monitoring surface deformation with spaceborne radar interferometry in landslide complexes: insights from the Brienz/Brinzauls slope instability, Swiss Alps
Authors: Manconi Andrea , Jones Nina , Loew Simon , Strozzi Tazio , Caduff Rafael , Wegmueller Urs 
Published: June 2024

AbstractWe performed an extensive analysis of C-band SAR datasets provided by the European Space Agency (ESA) satellites ERS-1/2, Envisat ASAR, and Sentinel-1 in the period 1992–2020 aiming at reconstructing the multi-decadal spatial and temporal evolution of the surface displacements at the Brienz/Brinzauls landslide complex, located in canton Graubünden (Switzerland). To this end, we analyzed about 1000 SAR images by applying differential interferometry (InSAR), multitemporal stacking, and persistent scatterer interferometry (PSI) approaches. Moreover, we jointly considered digital image correlation (DIC) on high-resolution multi-temporal digital terrain models (DTM) generated from airborne surveys and InSAR results to compute 3-D surface deformation fields. The extensive network of GNSS stations across the Brienz landslide complex allowed us to extensively validate the deformation results obtained in our remote sensing analyses. Here, we illustrate the limitations occurring when relying on InSAR and/or PSI measurements for the analysis and interpretation of complex landslide scenarios, especially in cases of relevant spatial and temporal heterogeneities of the deformation field. The joint use of InSAR and DIC can deliver a better picture of the evolution of the deformation field, however, not for all displacement components. Since InSAR, PSI and DIC measurements are nowadays routinely used in the framework of local investigations, as well as in regional, national, and/or continental monitoring programs, our results are of major importance for users aiming at a comprehensive understanding of these datasets in landslide scenarios.
Paternal Inheritance of Mitochondrial DNA May Lead to Dioecy in Conifers
Authors: de Jong Tom J. , Shmida Avi 
Published: June 2024

AbstractIn angiosperms cytoplasmic DNA is typically passed on maternally through ovules. Genes in the mtDNA may cause male sterility. When male-sterile (female) cytotypes produce more seeds than cosexuals, they pass on more copies of their mtDNA and will co-occur with cosexuals with a neutral cytotype. Cytoplasmic gynodioecy is a well-known phenomenon in angiosperms, both in wild and crop plants. In some conifer families (e.g. Pinaceae) mitochondria are also maternally inherited. However in some other families (e.g. Taxaceae and Cupressaceae) mtDNA is paternally inherited through the pollen. With paternal mtDNA inheritance, male cytotypes that produce more pollen than cosexuals are expected to co-occur with cosexuals. This is uncharted territory. An ESS model shows that the presence of male cytotypes selects for more female allocation in the cosexual, i.e. for sexual specialisation. An allele that switches sex from male to female can then invade. This leads to rapid loss of the neutral cytotype of the cosexual, fixation of the male cytotype and dioecy with 50% males and 50% females. The models suggest that paternal inheritance of mtDNA facilitates the evolution dioecy. Consistent with this hypothesis the Pinaceae are 100% monoecious, while dioecy is common in the Taxaceae family and in the genus Juniperus (Cupressaceae). However, no reliable data are yet available on both mode of inheritance of mtDNA and gender variation of the same species. When cosexuals benefit from reproductive assurance (high selfing rate, low inbreeding depression, low fertilisation) they maintain themselves next to males and females. This predicted pattern with three sex types present in the same population is observed in conifers in nature.
Multimodal vision-based human action recognition using deep learning: a review
Authors: Shafizadegan Fatemeh , Naghsh-Nilchi Ahmad R. , Shabaninia Elham 
Published: June 2024

AbstractVision-based Human Action Recognition (HAR) is a hot topic in computer vision. Recently, deep-based HAR has shown promising results. HAR using a single data modality is a common approach; however, the fusion of different data sources essentially conveys complementary information and improves the results. This paper comprehensively reviews deep-based HAR methods using multiple visual data modalities. The main contribution of this paper is categorizing existing methods into four levels, which provides an in-depth and comparable analysis of approaches in various aspects. So, at the first level, proposed methods are categorized based on the employed modalities. At the second level, methods categorized in the first level are classified based on the employment of complete modalities or working with missing modalities at the test time. At the third level, complete and missing modality branches are categorized based on existing approaches. Finally, similar frameworks in the third category are grouped together. In addition, a comprehensive comparison is provided for publicly available benchmark datasets, which helps to compare and choose suitable datasets for a task or to develop new datasets. This paper also compares the performance of state-of-the-art methods on benchmark datasets. The review concludes by highlighting several future directions.
A novel role of IGFBP5 in the migration, invasion and spheroids formation induced by IGF-I and insulin in MCF-7 breast cancer cells
Authors: Rodríguez-Rojas Karem , Cortes-Reynosa Pedro , Torres-Alamilla Pablo , Rodríguez-Ochoa Nínive , Salazar Eduardo Perez 
Published: June 2024

Abstract
Purpose
The insulin-like growth factor (IGF) system includes IGF-I, IGF-II insulin and their membrane receptors. IGF system also includes a family of proteins namely insulin-like growth factor-binding proteins (IGFBPs) composed for six major members (IGFBP-1 to IGFBP6), which capture, transport and prolonging half-life of IGFs. However, it has been described that IGFBPs can also have other functions.

Methods
IGFBP5 expression was inhibited by shRNAs, migration was analyzed by scratch-wound assays, invasion assays were performed by the Boyden chamber method, spheroids formation assays were performed on ultra-low attachment surfaces, expression and phosphorylation of proteins were analyzed by Western blot.

Results
IGFBP5 is a repressor of IGF-IR expression, but it is not a repressor of IR in MCF-7 breast cancer cells. In addition, IGFBP5 is a suppressor of migration and MMP-9 secretion induced by IGF-I and insulin, but it does not regulate invasion in MCF-7 cells. IGFBP5 also is a repressor of MCF-7 spheroids formation. However treatment with 340 nM rescues the inhibitory effect of IGFBP in the MCF-7 spheroids formation.

Conclusion
IGFBP5 regulates IGF-IR expression, migration and MMP-9 secretion induced by IGF-I and/or insulin, and the spheroids formation in MCF-7 breast cancer cells.
“The Union of the Soul and the Body”: Merleau-Ponty on Being in the World
Authors: Wehinger Daniel 
Published: June 2024

AbstractMerleau-Ponty’s theory of the body is often depicted as emphasizing the distinction between the physical and the conscious dimension of the body. This distinction, however, runs the risk of recreating the tension between the physical and the conscious that is at the center of the mind-body problem. In view of this, I argue for a different interpretation of Merleau-Ponty, according to which his theory of the body is an attempt to establish “the union of the soul and the body” (Merleau-Ponty, 2012: 91, 99) by way of an analysis of the phenomenon of being in the world. This phenomenon does not just go beyond reflective but also beyond pre-reflective consciousness. It is an essential feature of living beings that has a teleological structure and that stands in the way of a reduction of living beings to physical objects. In the end, Merleau-Ponty argues for an antireductionist and metaphysically quite charged concept of life that is supposed to bridge the gap between the conscious and the organic dimension of human existence and that holds important insights for the contemporary debates on minimal consciousness, the life-mind continuity, autopoietic enactivism, and causation.
Effects of particle surface modification on magnetic behavior of soft magnetic Fe@SiO2 composites and Fe compacts
Authors: Maciaszek Robert , Kollár Peter , Birčáková Zuzana , Tkáč Martin , Füzer Ján , Olekšáková Denisa , Volavka Dominik , Samuely Tomáš , Kováč Jozef , Bureš Radovan , Fáberová Mária 
Published: June 2024

AbstractThe study aims to evaluate the influence of surface modification of Fe powder on the magnetic behavior of soft magnetic compacts and composites that can possibly enhance their properties. The smoothing of ferromagnetic particle surfaces led to a decrease in the total energy loss as the most evident positive impact in all investigated classes (max. by 11% for small, 63–125 μm particle-based annealed Fe compacts, at max. induction 0.5 T and frequency 100 Hz) and to a partial increase in specific electrical resistivity (max. by 47% for small particle-based Fe@SiO2 composites) and resonant frequency (max. by 48% for large, 200–400 μm particle-based Fe@SiO2 composites) as well as partial decrease in coercivity (max. by 14% for small particle-based annealed Fe compacts). Removing surface irregularities negatively affected the maximum total permeability (max. drop by 28% for large particle-based Fe@SiO2 composites) due to increased inner demagnetizing fields. Applying the Bertotti theory for loss separation, we obtained parameters of loss components and assumed the domain structure using simultaneously active magnetic objects as predictors. The total loss decrease observed after the smoothing process originates from the significantly increased numbers of active magnetic objects, facilitating AC magnetization reversal so that domain wall displacements are accompanied by lower energy loss, manifested as a decrease in the excess loss component (max. by 61% for small particle-based Fe@SiO2 composites).