bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tackling capacitive coupling in broad-band spectral electrical impedance tomography (sEIT) measurements by selecting electrode configurations
Authors: Wang Haoran , Huisman Johan Alexander , Zimmermann Egon , Vereecken Harry 
Published: April 2024

SUMMARY
Electromagnetic (EM) coupling effects including both inductive and capacitive coupling have long been an essential problem in broad-band spectral electrical impedance tomography (sEIT) measurements at the field scale. Efforts have been made to remove EM coupling numerically or to suppress the effects by modified data acquisition strategies. For near-surface applications with relatively small survey layouts, inductive coupling can be well removed in the mHz to kHz frequency range. With the use of shielded coaxial cables and so-called active electrodes where the amplifiers are mounted at the electrodes, capacitive coupling in sEIT measurements can also be reduced. However, it remains challenging to cope with capacitive coupling between the cable shield and the ground, especially in resistive field conditions. The aim of this study is to deal with this type of capacitive coupling effect by identifying and filtering out sEIT measurements that are strongly affected by capacitive coupling. Based on a correction method for capacitive coupling proposed in a previous study, an approach to estimate measurement errors due to capacitive coupling is presented first. In the second step, a workflow was proposed to calculate the capacitive coupling strength (CCS) for each electrode configuration, which is defined as the ratio of the imaginary part of the impedance induced by capacitive coupling and the imaginary part of the impedance due to the subsurface electrical conductivity. In the final step, measurements with low CCS were selected for inversion and the results were compared with inversion results obtained using the previously developed correction approach. It was found that the filtering method based on CCS is more capable in tackling capacitive coupling compared to using model-based corrections. Spectrally consistent sEIT results up to kHz were obtained using the newly developed filtering method, which were not achieved in previous work using model-based correction.
Role of Supplemental Breast MRI in Screening Women with Mammographically Dense Breasts: A Systematic Review and Meta-analysis
Authors: Faheem Michael , Tam Hui Zhen , Nojoum Magd , Suaris Tamara , Jahan Noor , Lloyd Thomas , Johnson Laura , Aggarwal Shweta , Ullah MdZaker , Thompson Erik W , Brentnall Adam R 
Published: April 2024

Abstract

Background
High mammographic density increases breast cancer risk and reduces mammographic sensitivity. We reviewed evidence on accuracy of supplemental MRI for women with dense breasts at average or increased risk.

Methods
PubMed and Embase were searched 1995-2022. Articles were included if women received breast MRI following 2D or tomosynthesis mammography. Risk of bias was assessed using QUADAS-2. Analysis used independent studies from the articles. Fixed-effect meta-analytic summaries were estimated for predefined groups (PROSPERO: 230277).

Results
Eighteen primary research articles (24 studies) were identified in women aged 19-87 years. Breast density was heterogeneously or extremely dense (BI-RADS C/D) in 15/18 articles and extremely dense (BI-RADS D) in 3/18 articles. Twelve of 18 articles reported on increased-risk populations. Following 21 440 negative mammographic examinations, 288/320 cancers were detected by MRI. Substantial variation was observed between studies in MRI cancer detection rate, partly associated with prevalent vs incident MRI exams (prevalent: 16.6/1000 exams, 12 studies; incident: 6.8/1000 exams, 7 studies). MRI had high sensitivity for mammographically occult cancer (20 studies with at least 1-year follow-up). In 5/18 articles with sufficient data to estimate relative MRI detection rate, approximately 2 in 3 cancers were detected by MRI (66.3%, 95% CI, 56.3%-75.5%) but not mammography. Positive predictive value was higher for more recent studies. Risk of bias was low in most studies.

Conclusion
Supplemental breast MRI following negative mammography in women with dense breasts has breast cancer detection rates of ~16.6/1000 at prevalent and ~6.8/1000 at incident MRI exams, considering both high and average risk settings.
Morphological and biochemical changes in Quercus humboldtii in response to warmer and polluted urban areas in a tropical Andean city
Authors: Camargo Miguel Angel , Melgarejo Luz Marina , Faerito Geisa , Pérez Ingry , Salgado-Negret Beatriz 
Published: April 2024

Abstract
The rapid growth of urban population has significantly changed human settlement patterns, leading to a decline in air quality and changes in climatic conditions in urban areas. Trees are recognized as nature-based solutions because they can remove particles from the air and regulate the climate. However, trees are negatively affected by pollution and temperatures, which represent a challenge for urban planning, management, and human health. To assess the impact of urban pollution and warmer climates on functional traits, we conducted a study using Quercus humboldtii, an endangered tree species endemic to Colombia and Panamá that dominates Andean forests and urban green areas in Bogotá. We selected three localities with contrasting pollution levels and climate conditions and measured 10 morphological and biochemical traits in six individuals at each location. Our findings revealed that Q. humboldtii adjusted morphological and biochemical traits in response to the environmental challenges posed by urban environments. The functional strategies varied between individuals with thin and large leaves and acidic pH in the colder and unpolluted native forest, while others displayed a conservative resource strategy (high leaf dry matter content) and neutral pH in the warmer and most polluted locality. Despite these differences, several traits indicate that Q. humboldtii is not a species tolerant to pollution. This is further supported by the air pollution tolerance index (APTI) values. Our results suggest that Q. humboldtii should be planted in areas of Bogotá with low pollution levels in order to promote its long-term survival and support ecosystem services.
Proteome reorganization and amino acid metabolism during germination and seedling establishment in Lupinus albus
Authors: Angermann Cecile , Heinemann Björn , Hansen Jule , Töpfer Nadine , Braun Hans-Peter , Hildebrandt Tatjana M 
Published: April 2024

Abstract
During germination plants rely entirely on their seed storage compounds to provide energy and precursors for the synthesis of macromolecular structures until the seedling has emerged from the soil and photosynthesis can be established. Lupin seeds use proteins as their major storage compounds, accounting for up to 40% of the seed dry weight. Lupins are therefore a valuable complement to soy as a source of plant protein for human and animal nutrition. The aim of this study was to elucidate how storage protein metabolism is coordinated with other metabolic processes to meet the requirements of the growing seedling. In a quantitative approach, we analysed seedling growth, as well as alterations in biomass composition, the proteome, and metabolite profiles during germination and seedling establishment in Lupinus albus. The reallocation of nitrogen resources from seed storage proteins to functional seed proteins was mapped based on a manually curated functional protein annotation database. Although classified as a protein crop, Lupinus albus does not use amino acids as a primary substrate for energy metabolism during germination. However, fatty acid and amino acid metabolism may be integrated at the level of malate synthase to combine stored carbon from lipids and proteins into gluconeogenesis.
Operating Principles From the Digital Battle Space That Could Benefit the Digital Care Space
Authors: Vigilante Kevin , Kizer Kenneth W , Escaravage Steven 
Published: April 2024

Abstract
The promise of digital tools to dramatically improve health care remains largely unfulfilled, creating frustration for both patients and providers. Additionally, these tools are increasingly vulnerable to cyber attack and deep fakes. The digital battle space has progressed rapidly to address similar challenges and offers valuable lessons for health care. In this article we explore how six principles from the digital battle space can be applied to the digital care space.
The uS10c-BPG2 module mediates ribosomal RNA processing in chloroplast nucleoids
Authors: Sun Xueping , Singla-Rastogi Meenu , Wang Jingwen , Zhao Chuanzhi , Wang Xingjun , Li Pengcheng 
Published: April 2024

Abstract
In plant chloroplasts, certain ribosomal proteins (RPs) and ribosome biogenesis factors (RBFs) are present in nucleoids, implying an association between nucleoids and ribosome biogenesis. In Arabidopsis, the YqeH-type GTPase Brassinazole-Insensitive Pale Green2 (BPG2) is a chloroplast nucleoid-associated RBF. Here, we investigated the relationship between nucleoids and BPG2-involved ribosome biogenesis steps by exploring how BPG2 targets ribosomes. Our findings demonstrate that BPG2 interacts with an essential plastid RP, uS10c, in chloroplast nucleoids in a ribosomal RNA (rRNA)-independent manner. We also discovered that uS10c is a haploinsufficient gene, as the heterozygous deletion of this gene leads to variegated shoots and chlorophyll aggregation. uS10c is integrated into 30S ribosomal particles when rRNA is relatively exposed and also exists in polysome fractions. In contrast, BPG2 exclusively associates with 30S ribosomal particles. Notably, the interaction between BPG2 and 30S particles is influenced by the absence of uS10c, resulting in BPG2 diffusing in chloroplasts instead of targeting nucleoids. Further, our results reveal that the loss of BPG2 function and the heterozygous deletion of uS10c impair the processing of 16S and 23S-4.5S rRNAs, reduce plastid protein accumulation, and trigger the plastid signaling response. Together, these findings indicate that the uS10c-BPG2 module mediates ribosome biogenesis in chloroplast nucleoids.
Do all Emergency Room Patients With Influenza-like Symptoms Need Blood Cultures? A Retrospective Cohort Study of 2 Annual Influenza Seasons
Authors: Ehrhard Simone , Herren Lukas , Ricklin Meret E , Suter-Riniker Franziska , Exadaktylos Aristomenis K , Hautz Wolf , Müller Martin , Jent Philipp 
Published: April 2024

Abstract
In this retrospective cohort study, we evaluated risk factors for bacteremia in emergency department patients presenting with influenza-like symptoms during influenza epidemic seasons. In patients without fever, chronic heart or chronic liver disease, blood culture collection might be omitted.
Genomic Surveillance of Invasive Meningococcal Disease During a National MenW Outbreak in Australia, 2017–2018
Authors: Sotheran Emily , Lane Courtney R , Horan Kristy , Stevens Kerrie , Guglielmino Christine , Bradbury Susan , Kennedy Karina , Cooley Louise , McEwan Belinda , Kahler Charlene M , Mowlaboccus Shakeel , Speers David J , Baird Robert , Freeman Kevin , Leong Lex , Warner Morgyn , Williamson Deborah A , McVernon Jodie , Lahra Monica , Jennison Amy V , Howden Benjamin P , Andersson Patiyan 
Published: April 2024

Abstract

Background
In Australia, invasive meningococcal disease (IMD) incidence rapidly increased between 2014 and 2017 due to rising serogroup W (MenW) and MenY infections. We aimed to better understand the genetic diversity of IMD during 2017 and 2018 using whole genome sequencing data.

Methods
Whole genome sequencing data from 440 Australian IMD isolates collected during 2017 and 2018 and 1737 international MenW:CC11 isolates collected in Europe, Africa, Asia, North America, and South America between 1974 and 2020 were used in phylogenetic analyses; genetic relatedness was determined from single-nucleotide polymorphisms.

Results
Australian isolates were as follows: 181 MenW (41%), 144 MenB (33%), 88 MenY (20%), 16 MenC (4%), 1 MenW/Y (0.2%), and 10 nongenogroupable (2%). Eighteen clonal complexes (CCs) were identified, and 3 (CC11, CC23, CC41/44) accounted for 78% of isolates (343/440). These CCs were associated with specific serogroups: CC11 (n = 199) predominated among MenW (n = 181) and MenC (n = 15), CC23 (n = 80) among MenY (n = 78), and CC41/44 (n = 64) among MenB (n = 64). MenB isolates were highly diverse, MenY were intermediately diverse, and MenW and MenC isolates demonstrated the least genetic diversity. Thirty serogroup and CC-specific genomic clusters were identified. International CC11 comparison revealed diversification of MenW in Australia.

Conclusions
Whole genome sequencing comprehensively characterized Australian IMD isolates, indexed their genetic variability, provided increased within-CC resolution, and elucidated the evolution of CC11 in Australia.
Qualitative Research in Health and Illness
Authors: Gullion Jessica Smartt 
Published: April 2024

Abstract
This book is an accessible introduction to doing qualitative inquiry. Through exploration of research ethics, study design, data collection, data analysis, writing, and other topics, students learn how to conduct their own qualitative research. Although students of any discipline will find this text helpful, it specifically will be of interest to students in health-related fields, including nursing, health studies, kinesiology, public health, physical/occupational therapy, health care administration, nutrition, medical sociology, and medical anthropology. The book can be used at both the upper level undergraduate and the graduate level. This book can also be used by health care practitioners and faculty interested in learning how to conduct qualitative research.
The Promise of ‘Peace through Law’ in the Shadow of War
Authors: Simon Hendrik 
Published: April 2024

Abstract
The Franco-Prussian War (1870/71) was arguably the most important historical caesura in the European legal discourse: Chapter 6 first refers to the professionalization of international legal scholarship around the 1870s (Chapter 6.2) before discussing the continuities and changes in liberal thinking about war and peace (Chapter 6.3). Liberal international legal scholars not only referred to Kant’s plan of an ‘outlawry of war’, but also to ‘old’ narratives of morality and natural law. The liberal legal scholars thus fluctuated in their thinking somewhere between Grotius and Kant. At the same time, liberal legal thinking on peace was not free of ambivalences. While they were in favour of peace through law, some liberal scholars developed justifications for wars of national unification (Chapter 6.4). This is a particularly clear example of the nineteenth-century paradoxes of nationalism and internationalism. But liberal legal discourse was also strongly influenced by colonialist, racist, chauvinist, and antisemitic narratives. One exception was a particularly progressive Kantian—Walther Schücking. In his reflexive approach to the ambivalences of liberal legal thought, Schücking consistently strove for ius contra bellum (Chapter 6.5) and thus underlined the importance that this legal political demand had gained at the end of the nineteenth century. A clear rejection of a ‘free right to go to war’!
A Hegemonic Discourse? On Mainstream(s) and Myth(s)
Authors: Simon Hendrik 
Published: April 2024

Abstract
Was the thesis of liberum ius ad bellum influential beyond Germany? Chapter 8 shows that the mainstream of legal scholars in Europe clearly opposed the German ‘outsiders’. It argues that, in the last third of the nineteenth century, discussions between realist and liberal scholars in Europe anticipated the First Great Debate in International Relations, which is usually dated to the mid-twentieth century. What is striking is how, in this transdisciplinary debate, the arguments between the primates of law and politics, on one hand, and the military, on the other, were exchanged and related to each other in an antithetical manner.
Antinomianism
Authors: Simon Hendrik 
Published: April 2024

Abstract
Chapter 9 turns to the German politics of justifying military force between 1870/71 and 1918. The chapter’s focus is on the genesis of Notstand (‘necessity’) as a narrative of justification. While studies on the necessity of war have mainly focused on ius in bello, the chapter points to Germany’s reservations regarding efforts to foster ius contra bellum, as discussed in the context of the Hague Peace Conferences (Chapter 9.2). Subsequently, the chapter addresses the Kaiserreich’s war justifications in the context of the First World War (Chapter 9.3). While Germany did not explicitly claim a ‘free right to wage war’, it justified blatant violations of the norms of ius contra bellum and ius in bello with reference to Notwehr (‘self-defence’) and broad interpretations of Notstand (‘necessity’). In its eclectic use of both the Clausewitzian legal theory of liberum ius ad bellum and elements of the European war discourse, the Kaiserreich attempted to create alternative normative facts. As is shown in reference to European reactions, Germany pursued a ‘special path’ (Sonderweg) in its politics of justifying war—one which was not accepted by the international legal community.
Flattery in Seneca the Younger
Authors: Russo Martina 
Published: April 2024

Abstract
Flattery in Seneca the Younger: Theory and Practice explores the discourse of flattery in Seneca’s philosophical texts and the extent to which Seneca developed a theory of adulation. The personal practice of flattery displayed in the Ad Polybium and in De clementia along with the ‘distant’ exempla of flattery represented by Seneca indicates the range of strategic flattery during the Julio-Claudian dynasty. Seneca emerges as a practitioner and as a theorist of flattery. Seneca not only accepts flattery but also advocates it as an essential tool. Nevertheless, in Seneca’s philosophical prose a constant tension emerges: whereas flattery is ‘politically’ acceptable as an instrument to cope with the absolute power embraced by the princeps, the sapiens and the proficiens should be careful because flattery can compromise their path to wisdom. The volume discusses how passages permeated with the most blatant flattery can be read on a new level, viewing Seneca’s philosophical prose as an exercise in symbolic projection behind the façade of the most flagrant flattery.
Polybius’ hilariora studia
Authors: Russo Martina 
Published: April 2024

Abstract
By exploring the possible link between Polybius and Seneca, Chapter 2 attempts to explain why Seneca chooses to address Polybius among Claudius’ freedmen, and not the more powerful Pallas or Narcissus, by focusing on the relevance of literature in the consolation. As part of his stratagem to draw Claudius’ attention to his situation, Seneca describes the freedman not only as a zealous imperial functionary but as an outstanding scholar. Rereading Polybius not simply as the material executor of the emperor but also as an eminent intellectual helps us to acknowledge the great relevance of literary culture in the first century. The chapter focuses on Seneca’s depiction of Polybius as a highly cultured freedman, who has to celebrate Claudius’ res gestae, and then turns to a less demanding literary genre. It will be revealed that the omission of Phaedrus opens up a complex operation of censorship which has considerable social and political repercussions.
Experiential Representation and Disabled People’s Interests
Authors: Evans Elizabeth , Reher Stefanie 
Published: April 2024

Abstract
Do political representatives who identify as disabled refer to their own lived experience in the process of political deliberation and policy-making, and how? Do they use this experience to represent the interests of disabled citizens? To answer these questions, and the wider question of how the presence of disabled people in parliaments matters, the chapter provides analysis of the political speeches and activities of disabled MPs going back to 1866. Moreover, it draws upon interviews with disabled politicians and disability rights campaigners to understand the links between lived experience of disability and representation. The study finds that many disabled politicians are indeed active representatives of disabled people, and that disabled activists believe that lived experience is necessary for the good representation of disabled people. At times, the specific nature of particular impairments or conditions also becomes relevant and is addressed by representatives. The chapter concludes that, while non-disabled people can and do also play an important role in developing disability policy, the lived experience of disability enhances the representation of disabled people’s issues and interests.
The 3 Regional Human Rights Courts in Context
Authors: Burgorgue-Larsen Laurence 
Published: April 2024

Abstract
The book takes a critically engaged look at both the creation and the workings of the three regional human rights systems, of which the 3 Courts are the jewels in the crown, so to speak. It is the first to offer a comprehensive legal and political–scientific analysis comparing the three systems. Rather than merely juxtaposing analogous features in each system, it compares and contrasts each within an integrated whole. It also includes historical, political, and sociological insights and observations alongside its primary legal focus—hence the ‘in context’ in the title. A close analysis of the processes by which the systems came into being makes it clear that, regardless of distinctive political, cultural, and other factors, states on each of the three continents have chafed hard at the bit of international supervision. The commonly accepted wisdom that, after the Second World War, the ethical, cultural, and political thrust of the human rights project was so powerful that states simply did not need to discuss it, is no longer tenable. The subtitle of the book—Justice That Cannot Be Taken for Granted—underscores this key point, which is buttressed further by analyses of how each system has evolved and how the rulings of each court have been implemented.
Shaky Legitimacy
Authors: Burgorgue-Larsen Laurence 
Published: April 2024

Abstract
Chapter 3 discusses the complexities around attempts to establish the legitimacy of the 3 Courts. Based on recent work—specifically a volume edited by Nienke Grossman et al.—the chapter approaches the problem from two angles. First there is the choice of what rights are to be protected: whether states agree to add rights to those of each system covered when it was set up. Then there is the selection of judges, with states determined at all costs to maintain control over internal selection procedures. The chapter’s analysis makes clear that, even after it seems to have been established, the Courts’ legitimacy still cannot be said to be on solid ground—far from it: it is particularly shaky, buffeted over time by a plethora of legal and political factors.
Persuasive Synergies
Authors: Burgorgue-Larsen Laurence 
Published: April 2024

Abstract
Chapter 6 highlights two key factors that persuade states to implement the judgments and jurisprudential standards developed by the courts—hence the title of the chapter, ‘Persuasive Synergies’. The first factor, constitutional persuasiveness, is of a strictly juridical nature and concerns the ways in which the constitutions of the three continents do or do not make room for international human rights law. The second, dialogic persuasiveness, goes beyond the juridical realm, taking in various types of dialogue set up between the 3 Courts and various domestic actors such as judges, bodies set up to protect human rights, such as the national human rights institutions, various academic entities, and NGOs.