bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical reappraisal of the composite international diagnostic interview version 3.3 in Qatar's National Mental Health Study
Authors: Khaled Salma M. , Amro Iman , Abdelkader Menatalla , Al Bahari Dalia , Al Shawwaf Mahmoud , Alabdulla Majid , Alhassan Ahmed , Ali Amal , Aly Sheeren , Amin Asmaa , Chiu Wai Tat , Currie James , El Fakki Hana , First Michael B. , Hassan Mohammed H. O. , Hijawi Zainab , Mohammed Rumaisa , Nofal Marwa , Salman Salma , Sampson Nancy A. , Woodruff Peter W. , Kessler Ronald C. 
Published: May 2024

AbstractObjectivesLifetime DSM‐5 diagnoses generated by the lay‐administered Composite International Diagnostic Interview for DSM‐5 (CIDI) in the World Mental Health Qatar (WMHQ) study were compared to diagnoses based on blinded clinician‐administered reappraisal interviews.MethodsTelephone follow‐up interviews used the non‐patient edition of the Structured Clinician Interview for DSM‐5 (SCID) oversampling respondents who screened positive for five diagnoses in the CIDI: major depressive episode, mania/hypomania, panic disorder, generalized anxiety disorder, and obsessive‐compulsive disorder. Concordance was also examined for a diagnoses of post‐traumatic stress disorder based on a short‐form versus full version of the PTSD Checklist for DSM‐5 (PCL‐5).ResultsInitial CIDI prevalence estimates differed significantly from the SCID for most diagnoses ( = 6.6–31.4, p = 0.010 < 0.001), but recalibration reduced most of these differences and led to consistent increases in individual‐level concordance (AU‐ROC) from 0.53–0.76 to 0.67–0.81. Recalibration of the short‐form PCL‐5 removed an initially significant difference in PTSD prevalence with the full PCL‐5 (from = 610.5, p < 0.001 to = 2.5, p = 0.110) while also increasing AU‐ROC from 0.76 to 0.81.ConclusionsRecalibration resulted in valid diagnoses of common mental disorders in the Qatar National Mental Health Survey, but with inflated prevalence estimates for some disorders that need to be considered when interpreting results.
Alternating low‐rank tensor reconstruction for improved multiparametric mapping with cardiovascular MR Multitasking
Authors: Cao Tianle , Hu Zheyuan , Mao Xianglun , Chen Zihao , Kwan Alan C. , Xie Yibin , Berman Daniel S. , Li Debiao , Christodoulou Anthony G. 
Published: May 2024

AbstractPurposeTo develop a novel low‐rank tensor reconstruction approach leveraging the complete acquired data set to improve precision and repeatability of multiparametric mapping within the cardiovascular MR Multitasking framework.MethodsA novel approach that alternated between estimation of temporal components and spatial components using the entire data set acquired (i.e., including navigator data and imaging data) was developed to improve reconstruction. The precision and repeatability of the proposed approach were evaluated on numerical simulations, 10 healthy subjects, and 10 cardiomyopathy patients at multiple scan times for 2D myocardial T1/T2 mapping with MR Multitasking and were compared with those of the previous navigator‐derived fixed‐basis approach.ResultsIn numerical simulations, the proposed approach outperformed the previous fixed‐basis approach with lower T1 and T2 error against the ground truth at all scan times studied and showed better motion fidelity. In human subjects, the proposed approach showed no significantly different sharpness or T1/T2 measurement and significantly improved T1 precision by 20%–25%, T2 precision by 10%–15%, T1 repeatability by about 30%, and T2 repeatability by 25%–35% at 90‐s and 50‐s scan times The proposed approach at the 50‐s scan time also showed comparable results with that of the previous fixed‐basis approach at the 90‐s scan time.ConclusionThe proposed approach improved precision and repeatability for quantitative imaging with MR Multitasking while maintaining comparable motion fidelity, T1/T2 measurement, and septum sharpness and had the potential for further reducing scan time from 90 s to 50 s.
Low‐rank reconstruction for simultaneous double half‐echo 23Na and undersampled 23Na multi‐quantum coherences MRI
Authors: Licht Christian , Reichert Simon , Bydder Mark , Zapp Jascha , Corella Shirley , Guye Maxime , Zöllner Frank G. , Schad Lothar R. , Rapacchi Stanislas 
Published: May 2024

AbstractPurposeTo develop a new sequence to simultaneously acquire Cartesian sodium (23Na) MRI and accelerated Cartesian single (SQ) and triple quantum (TQ) sodium MRI of in vivo human brain at 7 T by leveraging two dedicated low‐rank reconstruction frameworks.Theory and MethodsThe Double Half‐Echo technique enables short echo time Cartesian 23Na MRI and acquires two k‐space halves, reconstructed by a low‐rank coupling constraint. Additionally, three‐dimensional (3D) 23Na Multi‐Quantum Coherences (MQC) MRI requires multi‐echo sampling paired with phase‐cycling, exhibiting a redundant multidimensional space. Simultaneous Autocalibrating and k‐Space Estimation (SAKE) were used to reconstruct highly undersampled 23Na MQC MRI. Reconstruction performance was assessed against five‐dimensional (5D) CS, evaluating structural similarity index (SSIM), root mean squared error (RMSE), signal‐to‐noise ratio (SNR), and quantification of tissue sodium concentration and TQ/SQ ratio in silico, in vitro, and in vivo.ResultsThe proposed sequence enabled the simultaneous acquisition of fully sampled 23Na MRI while leveraging prospective undersampling for 23Na MQC MRI. SAKE improved TQ image reconstruction regarding SSIM by 6% and reduced RMSE by 35% compared to 5D CS in vivo. Thanks to prospective undersampling, the spatial resolution of 23Na MQC MRI was enhanced from mm3 to mm3 while reducing acquisition time from min to min.ConclusionThe proposed sequence, coupled with low‐rank reconstructions, provides an efficient framework for comprehensive whole‐brain sodium MRI, combining TSC, T2*, and TQ/SQ ratio estimations. Additionally, low‐rank matrix completion enables the reconstruction of highly undersampled 23Na MQC MRI, allowing for accelerated acquisition or enhanced spatial resolution.
Unwrapping phase contrast MRI by iterative graph cuts
Authors: Berglund Johan , Liljeblad Mio , Baron Tomasz 
Published: May 2024

AbstractPurposeTo develop and evaluate a phase unwrapping method for cine phase contrast MRI based on graph cuts.MethodsA proposed Iterative Graph Cuts method was evaluated in 10 cardiac patients with two‐dimensional flow quantification which was repeated at low venc settings to provoke wrapping. The images were also unwrapped by a path‐following method (ROMEO), and a Laplacian‐based method (LP). Net flow was quantified using semi‐automatic vessel segmentation. High venc images were also wrapped retrospectively to asses the residual amount of wrapped voxels.ResultsThe absolute net flow error after unwrapping at venc = 100 cm/s was 1.8 mL, which was 0.83 mL smaller than for LP. The repeatability error at high venc without unwrapping was 2.5 mL. The error at venc = 50 cm/s was 7.5 mL, which was 8.2 mL smaller than for ROMEO and 5.7 mL smaller than for LP. For retrospectively wrapped images with synthetic venc of 100/50/25 cm/s, the residual amount of wrapped voxels was 0.00/0.12/0.79%, which was 0.09/0.26/8.0 percentage points smaller than for LP. With synthetic venc of 25 cm/s, omitting magnitude information resulted in 3.2 percentage points more wrapped voxels, and only spatial/temporal unwrapping resulted in 4.6/21 percentage points more wrapped voxels compared to spatiotemporal unwrapping.ConclusionIterative Graph Cuts enables unwrapping of cine phase contrast MRI with very small errors, except for at extreme blood velocities, with equal or better performance compared to ROMEO and LP. The use of magnitude information and spatiotemporal unwrapping is recommended.
Collagen degradation assessment with an in vitro rotator cuff tendinopathy model using multiparametric ultrashort‐TE magnetization transfer (UTE‐MT) imaging
Authors: Guo Tan , Song Yan , Tong Jinlian , Jiao Sheng , Shen Cheng , Wang Hong , Cui Ju , Dai Dapeng , Ma Jie , Chen Min 
Published: May 2024

AbstractPurposeThis study aims to assess ultrashort‐TE magnetization transfer (UTE‐MT) imaging of collagen degradation using an in vitro model of rotator cuff tendinopathy.MethodsThirty‐six supraspinatus tendon specimens were divided into three groups and treated with 600 U collagenase (Group 1), 150 U collagenase (Group 2), and phosphate buffer saline (Group 3). UTE‐MT imaging was performed to assess changes in macromolecular fraction (MMF), macromolecule transverse relaxation time (T2m), water longitudinal relaxation rate constant (R1m), the magnetization exchange rate from the macromolecular to water pool (Rm0w) and from water to the macromolecular pool (Rm0m), and magnetization transfer ratio (MTR) at baseline and following digestion and their differences between groups. Biochemical and histological studies were conducted to determine the extent of collagen degradation. Correlation analyses were performed with MMF, T2m, R1m, Rm0w, Rm0m, and MTR, respectively. Univariate and multivariate linear regression analyses were performed to evaluate combinations of UTE‐MT parameters to predict collagen degradation.ResultsMMF, T2m, R1m, Rm0m, and MTR decreased after digestion. MMF (r = −0.842, p < 0.001), MTR (r = −0.78, p < 0.001), and Rm0m (r = −0.662, p < 0.001) were strongly negatively correlated with collagen degradation. The linear regression model of differences in MMF and Rm0m before and after digestion explained 68.9% of collagen degradation variation in the tendon. The model of postdigestion in MMF and T2m and the model of MTR explained 54.2% and 52.3% of collagen degradation variation, respectively.ConclusionThis study highlighted the potential of UTE‐MT parameters for evaluation of supraspinatus tendinopathy.
Accelerated 3D multi‐echo spin‐echo sequence with a subspace constrained reconstruction for whole mouse brain T2 mapping
Authors: Trotier Aurélien J. , Corbin Nadège , Miraux Sylvain , Ribot Emeline J. 
Published: May 2024

AbstractPurposeTo accelerate whole‐brain quantitative mapping in preclinical imaging setting.MethodsA three‐dimensional (3D) multi‐echo spin echo sequence was highly undersampled with a variable density Poisson distribution to reduce the acquisition time. Advanced iterative reconstruction based on linear subspace constraints was employed to recover high‐quality raw images. Different subspaces, generated using exponential or extended‐phase graph (EPG) simulations or from low‐resolution calibration images, were compared. The subspace dimension was investigated in terms of precision. The method was validated on a phantom containing a wide range of and was then applied to monitor metastasis growth in the mouse brain at 4.7T. Image quality and estimation were assessed for 3 acceleration factors (6/8/10).ResultsThe EPG‐based dictionary gave robust estimations of a large range of . A subspace dimension of 6 was the best compromise between precision and image quality. Combining the subspace constrained reconstruction with a highly undersampled dataset enabled the acquisition of whole‐brain maps, the detection and the monitoring of metastasis growth of less than 500 .ConclusionSubspace‐based reconstruction is suitable for 3D mapping. This method can be used to reach an acceleration factor up to 8, corresponding to an acquisition time of 25 min for an isotropic 3D acquisition of 156 m on the mouse brain, used here for monitoring metastases growth.
A FEM/DEM adaptive remeshing strategy for brittle elastic failure initiation and propagation
Authors: Yahya Farouk , Hubert Cédric , Leconte Nicolas , Dubar Laurent 
Published: May 2024

AbstractThis article presents an adaptive remeshing strategy between the finite element method (FEM) and the discrete element method (DEM). To achieve this strategy, an edge‐to‐edge coupling method based on Lagrange multipliers has been set‐up to ensure the continuity of velocities at the interface. To switch from a computation initially purely FEM to a FEM‐DEM one, a field transfer method was required. In particular, a displacement field transfer method has been set‐up. The switching from a FEM subdomain to a DEM one is activated by a transition criterion. Each time a FEM subdomain is substituted by a DEM one, the DEM subdomain microscopic properties are set‐up with respect to the subdomain geometry and desired particle refinement. This is performed thanks to the linking to the so‐called “Cooker,” a tool distributed along with the GranOO Workbench. Two subdomain remeshing cases were dealt with: that of an initially FEM subdomain that is converted to DEM, and that of DEM subdomains which coalesce. A numerical test case shows that the dynamic remeshing method behaves as expected: FEM subdomains are substituted by DEM ones when the transition criterion is met, and DEM subdomains coalesce when required. The final numerical test case shows a good agreement with a crack propagation experiment of the literature, while a speedup of about 20 was observed when compared to pure DEM computation.
Daily experiences of non‐psychiatric nurses in acute psychiatric wards
Authors: Rangwaneni Mphedziseni Esther , Raliphaswa Ndidzulafhi Selina , Maluleke Mary , Masutha Thingahangwi Cecilia 
Published: May 2024

AbstractAimTo explore and describe the daily experiences of non‐psychiatric nurses working in selected acute psychiatric wards in South Africa.DesignA qualitative explorative and descriptive study design was used.MethodsIndividual face‐to‐face semi‐structured interviews were used to gather data from fifteen non‐psychiatric nurses with a minimum of one month of experience working in acute psychiatric wards in Limpopo Province, South Africa. Data were analysed using eight Tech techniques. The study is reported following consolidation criteria for reporting qualitative research.ResultsFindings on non‐psychiatric nurses' daily experience revealed three themes: (1) Unsafe working environment, (2) Managing difficulties due to lack of skills and (3) Strategies to support non‐psychiatric nurses in acute psychiatric wards.Findings suggested institutional and managerial interventions in the form of orientation, in‐service training and workshops and resource provision. Future studies should be done to develop a model for supporting non‐psychiatric nurses in Limpopo Province, South Africa's acute psychiatric wards.
The psychological factors mediating/moderating the association between body‐image disturbance and depression: A systematic review
Authors: Wang Yiyi , Chen Yuqi , Lu Chenxuan , Kwan Angela T. H. , McIntyre Roger S. , Yang Fahui , Cao Bing 
Published: May 2024

AbstractAvailable evidence demonstrates that individuals with body‐image disturbance (BID) are prone to suffer from depression. This systematic review provides, to our knowledge, the first synthesis of the psychological mechanism of the association between BID and depression. We conducted a thorough search of online databases, including PubMed, Web of Science, and PsycINFO, for articles published up until February 2024. The final analysis comprised a total of 23 studies that focused on the mediating or moderating effects of psychological factors between depression and BID. This review identifies self‐esteem and social support as both mediators and moderators of the relationship between BID and depression, while perceived stress acted only as a mediator. High self‐esteem and strong social support as well as low levels of perceived stress may help individuals experience lower levels of BID, thereby contributing to a decreased likelihood of depression. Interventions aimed at increasing self‐esteem, developing strong support, and decreasing perceived stress may hold promise to reduce the risk of depression in those with BID.
Single‐cell proteomics by mass spectrometry: Advances and implications in cancer research
Authors: Tan Yong Chiang , Low Teck Yew , Lee Pey Yee , Lim Lay Cheng 
Published: May 2024

AbstractCancer harbours extensive proteomic heterogeneity. Inspired by the prior success of single‐cell RNA sequencing (scRNA‐seq) in characterizing minute transcriptomics heterogeneity in cancer, researchers are now actively searching for information regarding the proteomics counterpart. Therefore recently, single‐cell proteomics by mass spectrometry (SCP) has rapidly developed into state‐of‐the‐art technology to cater the need. This review aims to summarize application of SCP in cancer research, while revealing current development progress of SCP technology. The review also aims to contribute ideas into research gaps and future directions, ultimately promoting the application of SCP in cancer research.
Enhancement of thermoelectric performance of thienoisoindigo based D‐A conjugated polymers through the incorporation of 3,4‐ethylenedioxythiophene as donor unit
Authors: Zhang Yuhang , Lin Ting , Gao Yifei , Xu Chao , Li Hui , Li Pengcheng , Gao Xiang , Liu Zhitian 
Published: May 2024

AbstractWith the good planarity of conjugated backbone and high charge carrier mobilities, thienoisoindigo (TIIG)‐based polymers show great potential in organic electronic devices. In this work, two TIIG‐based D‐A conjugated polymers (PTIIG‐3T and PTIIG‐2T‐EDOT) were designed and synthesized, which exhibit high lying highest occupied molecular orbital (HOMO) energy level and can be facilely doped by FeCl3. Compared with PTIIG‐3T, one thiophene unit in the donor building block is replaced by 3,4‐ethylenedioxythiophene (EDOT) in PTIIG‐2T‐EDOT, and PTIIG‐2T‐EDOT shows a higher HOMO level with slightly higher coplanarity than PTIIG‐3T, which induce an enhancement in electrical conductivity after oxidation doping. After proper doping, doped PTIIG‐2T‐EDOT film achieved a higher TE power factor of 17.9 μW m−1 K−2 than that of PTIIG‐3T due to its higher conductivity. The results indicate that TIIG unit is a promising building block for future high‐performance conjugated polymers for thermoelectric applications, and incorporation of the EDOT unit into D‐A conjugated polymers could be an effective way to develop high performance thermoelectric polymers.
Chain branching during the polycondensation of isophthalic aldehyde and 1,1′‐diacetylferrocene by the Claisen–Schmidt reaction
Authors: Dvorikova Raisa , Khrustalev Victor , Ionova Irina , Mezhuev Yaroslav 
Published: May 2024

AbstractN‐methyl‐2‐pyrrolidone‐soluble ferrocene‐containing polychalcones, which are promising as a platform for the formation of ferromagnetic coatings after pyrolysis in an inert atmosphere is synthesized through the polycondensation of isophthalic aldehyde and 1,1′‐diacetylferrocene by the Claisen–Schmidt reaction. The structure and the molecular weight distribution of the polychalcones is characterized by NMR, IR spectroscopy, and size exclusion chromatography. It is shown that the formation of polychalcones is accompanied by chain branching via the Michael reactions and the aldol‐croton condensation. The structure of the linear fragments of the polychalcone chains is simulated with a tailored low‐molecular model compound, that is 1,3‐bis(3‐ferrocenyl‐1‐propen‐2‐one)benzene, which is characterized by the NMR and IR spectroscopy as well as the X‐ray diffraction analysis. The obtained results indicate an increasing tendency for polychalcone chain branching with the temperature growth during the Claisen–Schmidt reaction. The weight loss and the increase in magnetization under the conditions of pyrolysis of polychalcones at different temperatures is studied. The assumptions regarding the possible mechanisms of thermal destruction of ferrocene‐containing macromolecules are put forward.
Synthesis, optical properties, and dual‐color halochromic fluorescence of novel π‐conjugated polymers bearing coumarin unit in the main chain
Authors: Kaneko Yuya , Wang Aohan 
Published: May 2024

AbstractA series of novel π‐conjugated polymers bearing alternating coumarin and phenylene units in the main chain backbone was synthesized via Sonogashira coupling reaction. The red‐shifts in the absorption maxima of the polymers indicate the expansion of π‐conjugated system in the polymer main chains. These polymers exhibited strong green fluorescence in organic solvents. Clearly perceptible dual‐color halochromic fluorescence was confirmed for the polymers by the significantly reversible changes of emission color from green to blue during alkalization and acidification processes. The lactone ring opening and closing property in the coumarin molecule functioned as a controllable switch, broadening the applications of the coumarin‐based π‐conjugated polymers as acid–base responsive fluorescence materials.
Stereotactic body radiotherapy takes on Lung Oligometastases: Latest breakthroughs
Authors: Liu Xin , Wu Lei , Guo Tian , Huang Zhifeng , Chen Sen , Li ChenYang , Liu Qiufang , Wang Fenggang 
Published: May 2024

AbstractLung oligometastases represent an intermediate state of cancer dissemination between localized and widespread metastases. Stereotactic body radiation therapy (SBRT) has emerged as an effective treatment option, with an efficacy comparable to that of surgical resection. This review aimed to provide a comprehensive summary of the latest advancements and controversial issues regarding SBRT for lung oligometastases. It focuses on four crucial perspectives: efficacy of SBRT, optimal patient selection criteria, technological innovations, and synergistic effects of SBRT combined with systemic therapy. Relevant clinical trials investigating SBRT for lung oligometastases have been conducted, with median 1‐ and 5‐year local control rates of 90% and 79%, respectively. The origin of the primary tumor, size and number of lesions, and biomarker profiles were highlighted as pivotal considerations in patient selection. The precise dose delivery was enhanced using robotic SBRT and optimized dose fractionation schemes. Evidence suggests that dose escalation above 100 Gy biologically effective dose may improve tumor control. Combined immunotherapy and SBRT have demonstrated synergistic effects in prolonging progression‐free survival and overall survival. This review provides valuable insights into the precise treatment of oligometastatic lung diseases using SBRT. Further multicenter randomized trials are warranted to develop definitive patient selection criteria and optimize the integration with systemic therapies.