bluuebunny/crossref_metadata_2025_split huggingface dataset:
Helicoid end‐to‐side and oblique attachment technique in repair of the musculocutaneous nerve injury with the phrenic nerve as a donor: An experimental study in rats
Authors: Yan Yu‐Hui , Yan Ji‐Geng , Matloub Hani S. , Zhang Lin‐Ling , Hettinger Patrick , Sanger James , Jaradeh Safwan S. 
Published: January 2011

AbstractThe purpose of this study was to identify if a modified end‐to‐side repair can achieve equal results of nerve regeneration compared to an end‐to‐end repair using donor phrenic nerves in repair of the musculocutaneous nerve and also pulmonary protection. Eighteen rats were divided into three groups of six each comparing two nerve graft techniques: helicoid end‐to‐side plus distal oblique repair vs. traditional end‐to‐end repair, using a donor phrenic nerve. The saphenous nerve was used as a graft between the phrenic nerve and the musculocutaneous nerve. The third group was used as control; the musculocutaneous nerve was transected without any repair. Three months postoperatively, electrophysiology, tetanic force, moist muscle weight, histology, nerve fiber counting, and chest X‐ray were evaluated. All results have shown that this modified end‐to‐side repair was superior to the end‐to‐end repair. The former did not compromise the diaphragm function, but the latter showed an elevation of the diaphragm. Little recovery was seen in the third group. The conclusion is that this modified end‐to‐side repair can replace the traditional end‐to‐end repair using donor phrenic nerves with better results of nerve regeneration without diaphragm compromise. © 2011 Wiley‐Liss, Inc. Microsurgery, 2011.
Use of 1‐desamino‐8‐D‐arginine vasopressin in microsurgical reconstruction in a patient with von Willebrand's disease
Authors: Mithani Suhail K. , Davis Jared M. , Rodriguez Eduardo D. 
Published: January 2011

AbstractA 19‐year‐old male patient with type 1 von Willebrand's disease underwent two separate superficial inferior epigastric artery free flap tissue transfers and three revision procedures for reconstruction of a postextirpative mid‐facial defect. Intravenous 1‐desamino‐8‐D‐arginine vasopressin (DDAVP) was administered as bleeding prophylaxis prior to incision for free tissue transfer. For each debulking procedure, DDAVP was administered by intranasal sprays in minutes prior to incision and redosed 12 and 24 hours postoperatively. There were no incidents of either thrombosis or bleeding. This outcome indicates that 0.3 μg/kg intravenous DDAVP may be effective as bleeding prophylaxis for patients with mild and quantitative defects in von Willebrand factor undergoing microvascular reconstruction. © 2011 Wiley‐Liss, Inc. Microsurgery, 2011.
Hyaluronic acid biodegradable material for reconstruction of vascular wall: A preliminary study in rats
Authors: Pandis Laura , Zavan Barbara , Bassetto Franco , Ferroni Letizia , Iacobellis Laura , Abatangelo Giovanni , Lepidi Sandro , Cortivo Roberta , Vindigni Vincenzo 
Published: January 2011

AbstractThe objective of this preliminary study was to develop a reabsorbable vascular patch that did not require in vitro cell or biochemical preconditioning for vascular wall repair. Patches were composed only of hyaluronic acid (HA). Twenty male Wistar rats weighing 250–350 g were used. The abdominal aorta was exposed and isolated. A rectangular breach (1 mm × 5 mm) was made on vessel wall and arterial defect was repaired with HA made patch. Performance was assessed at 1, 2, 4, 8, and 16 weeks after surgery by histology and immunohistochemistry. Extracellular matrix components were evaluated by molecular biological methods. After 16 weeks, the biomaterial was almost completely degraded and replaced by a neoartery wall composed of endothelial cells, smooth muscle cells, collagen, and elastin fibers organized in layers. In conclusion, HA patches provide a provisional three‐dimensional support to interact with cells for the control of their function, guiding the spatially and temporally multicellular processes of artery regeneration. © 2011 Wiley‐Liss, Inc. Microsurgery, 2011.
Rectal distension: The effect on bladder function
Authors: Panayi D.C. , Khullar V. , Digesu G.A. , Spiteri M. , Hendricken C. , Fernando R. 
Published: January 2011

AbstractAimsTo assess how rectal distension affects urodynamics parameters and diagnosis.MethodsThirty women underwent filling cystometry with a rectal balloon inserted and filled with 150 ml of normal saline and repeated without the balloon distended. The volume at which first desire, strong desire and bladder capacity were reported by the women was recorded as well as urodynamics diagnosis. Women were randomized, using the closed envelope method, into having the rectal balloon distended during the first or during the second filling phase. Women with any bowel disease, history of bleeding per rectum were excluded, or women with any contraindication to undergoing urodynamics, or insertion of a device per rectum. All women of a reproductive age underwent pregnancy test and excluded if found to be pregnant.ResultsThirty patients were recruited, 16 reported mixed urinary incontinence (53%), 5 (17%) had isolated overactive bladder (OAB) symptoms and 9 (30%) reported isolated stress urinary incontinence. Patients with distended rectum had statistically significant lower bladder volumes at which first (46% reduction) and strong desire (33% reduction) was felt and reduced maximum bladder capacity (26% reduction) when compared to the rectum being undistended. In four patients (13%) with a history of OAB a diagnosis of detrusor overactivity was found with the rectum was distended but not when the rectum was empty.ConclusionRectal distension alters bladder sensation and in some cases urodynamics diagnosis. Neurourol. Urodynam. 30:344–347, 2011. © 2011 Wiley‐Liss, Inc.
L‐carnitine improves oxidative stress and suppressed energy metabolism but not renal dysfunction following release of acute unilateral ureteral obstruction in rat
Authors: Moosavi S. Mostafa Shid , Ashtiyani Saeed C. , Hosseinkhani Saman 
Published: January 2011

AbstractBackground and aimWe recently showed that L‐carnitine reduced oxidative stress and suppressed energy metabolism, while α‐tocopherol only prevented redox imbalance, in the obstructed kidney of rats subjected to 24‐hr of unilateral ureteral obstruction (UUO). The present study was undertaken to investigate the effects of both compounds on disturbed renal hemodynamics, solutes‐excretion, and urine‐concentrating ability as well as renal oxidative stress and suppressed metabolism at early hours following release of 24‐hr UUO.MethodsUUO was induced in anaesthetized rats that received L‐carnitine, α‐tocopherol or their vehicles in four different groups. Each rat was re‐anaesthetized, prepared for renal functional measurements, and its ureteral obstruction was released at 24‐hr. Then, urines of both kidneys were separately collected during 30–90 min of post‐release, with taking blood samples at beginning and end of it. Finally, both kidneys were removed and preserved at −80°C for future measuring their levels of ATP and ADP as well as malondialdehyde (MDA) and ferric reducing/antioxidant power (FRAP). There were also sham and control groups.ResultsPost‐obstructed kidney (POK) of vehicle‐treated groups compared to equivalent kidney of sham group had lower ATP, ATP/ADP, FRAP, creatinine clearance, absolute Na+‐ and K+‐excretion, and effective free‐water reabsorption, but higher MDA and ADP. L‐carnitine could improve oxidative stress and suppressed energy metabolism and α‐tocopherol normalized redox state, but both compounds did not have any effects on altered functional variables of the POK.ConclusionOxidative stress and suppressed energy metabolism may not be involved in the development of renal dysfunction during acute ureteral obstruction. Neurourol. Urodynam. 30:480–487, 2011. © 2011 Wiley‐Liss, Inc.
Coital incontinence: Relation to detrusor overactivity and stress incontinence
Authors: El‐Azab Ahmed S. , Yousef Hosam A. , Seifeldein Gehan S. 
Published: January 2011

AbstractAimsThe aim was to assess functional (demographic, clinical, and urodynamic) and anatomical (described by MRI) abnormalities associated with coital incontinence (CI).MethodsAll consecutive sexually active women with urinary incontinence (UI) were invited. Women were asked if they experience urine leakage during sex; and its timing: during penetration (CIAP) versus during orgasm (CIAO). All women were studied with urodynamics. Pelvic MRI was done for selected group of women. MRI examination was done using 1.5 T superconducting magnet, supine, and during two phases: static and dynamic, using multiplanar T2‐weighted turbo spin‐echo and single short T2‐wighted images.ResultsNinety women with UI; 60 had CI while 30 had no CI. Prevalence of CI was significantly higher among women with stress incontinence (SUI) (89.4%) compared to those with detrusor overactivity (DOA) (33.3%); P = 0.000. Factors significantly associated with CI were parity, prolapse, and SUI. Among studied MRI variables, no factor was significantly associated with CI. CI showed significant positive correlation with severity of SUI (r = 0.327, P = 0.05) and significant negative correlation with Abdominal leak point pressure (r = −0.362, P = 0.01). Amplitude of unstable detrusor contraction as measured by urodynamics did not correlate with severity of CI.ConclusionsCI seems to be in the spectrum of SUI and POP. CI is almost invariably a symptom of SUI with urethral sphincter incompetence, even when it occurs during orgasm. Many women with DOA leak during sex; however, the potential role of associated urethral incompetence should be considered. 30:520–524, 2011. © 2011 Wiley‐Liss, Inc.
Frequency offset dependence of adiabatic rotating frame relaxation rate constants: relevance to MRS investigations of metabolite dynamics in vivo
Authors: Mangia Silvia , Liimatainen Timo , Garwood Michael , Tkac Ivan , Henry Pierre‐Gilles , Deelchand Dinesh , Michaeli Shalom 
Published: January 2011

AbstractIn this work, we investigated the frequency‐offset dependence of the rotating frame longitudinal (R1ρ) and transverse (R2ρ) relaxation rate constants when using hyperbolic‐secant adiabatic full passage pulses or continuous‐wave spin‐lock irradiation. Phantom and in vivo measurements were performed to validate theoretical predictions of the dominant relaxation mechanisms existing during adiabatic full passage pulses when using different settings of the frequency offset relative to the carrier. In addition, adiabatic R1ρ and R2ρ values of total creatine and N‐acetylaspartate were measured in vivo from the human brain at 4 T. When the continuous‐wave pulse power was limited to safe specific absorption rates for humans, simulations revealed a strong dependence of R1ρ and R2ρ values on the frequency offset for both dipolar interactions and anisochronous exchange mechanisms. By contrast, theoretical and experimental results showed adiabatic R1ρ and R2ρ values to be practically invariant within the large subregion of the bandwidth of the hyperbolic‐secant pulse where complete inversion was achieved. However, adiabatic R1ρ and R2ρ values of the methyl protons of total creatine (at 3.03 ppm) were almost doubled when compared with those of the methyl protons of N‐acetylaspartate (at 2.01 ppm) in spite of the fact that these resonances were in the flat region of the inversion band of the adiabatic full passage pulses. We conclude that differences in adiabatic R1ρ and R2ρ values of human brain metabolites are not a result of their chemical shifts, but instead reflect differences in dynamics. Copyright © 2011 John Wiley & Sons, Ltd.
Quantification of myocardial blood flow and flow reserve in rats using arterial spin labeling MRI: comparison with a fluorescent microsphere technique
Authors: Jacquier Alexis , Kober Frank , Bun Soksithikun , Giorgi Roch , Cozzone Patrick J. , Bernard Monique 
Published: January 2011

AbstractTo quantify noninvasively myocardial blood flow (MBF) and MBF reserve in isoflurane‐anesthetized rats using the Look‐Locker flow‐alternating inversion recovery gradient‐echo arterial spin labeling technique (LLFAIRGE‐ASL), and to compare the results with the fluorescent microsphere (FM) technique. Male Wistar rats (weight = 200–240 g, n = 21) were anesthetized with 2.0% isoflurane. Hemodynamic parameters were recorded. In seven rats, MBF was assessed on a Bruker Biospec 4.7T MR system using an ECG‐ and respiration‐gated LLFAIRGE‐ASL (pixel size = 234 × 468µm2, TE = 1.52ms) at rest and during adenosine infusion (140 µg/kg/min). A mixture of 200 000 FM was injected into a second group of rats at rest and during adenosine infusion (n = 7 each), under similar physiologic conditions. Hearts and skeletal muscle samples were processed for fluorescence spectroscopy. Two‐tailed unpaired, paired Student's t‐test and ANOVAwere used to compare groups. MBF measured with LLFAIRGE‐ASL was 5.2 ± 1.0 mL/g/min at rest and 13.3 ± 3.0 mL/g/min during adenosine infusion. Results obtained with fluorescent microspheres yielded 5.9 ± 2.3 mL/g/min (nonsignificant vs. LLFAIRGE‐ASL, p = 0.9) at rest and 13.1 ± 2.1 mL/g/min (nonsignificant vs. LLFAIRGE‐ASL, p = 0.4) during adenosine infusion. Myocardial blood flow reserve measured using LLFAIRGE‐ASL and FM were not significantly different (2.5 ± 0.6 vs. 2.4 ± 0.9, respectively; p = 0.8). Hemodynamic parameters during the experiments were not different between the groups. The myocardial blood flow reserve determined under isoflurane anesthesia was 2.5 ± 0.6, which was not different from the value obtained with FM. LLFAIRGE‐ASL provided MBF maps with high spatial resolution in rats under isoflurane anesthesia. LLFAIRGE‐ASL is a noninvasive measure to assess myocardial blood flow reserve and provides an interesting tool for cardiovascular research. Copyright © 2011 John Wiley & Sons, Ltd.
K+ dynamics in ischemic rat brain in vivo by 87Rb MRI at 7 T
Authors: Yushmanov Victor E. , Kharlamov Alexander , Ibrahim Tamer S. , Zhao Tiejun , Boada Fernando E. , Jones Stephen C. 
Published: January 2011

AbstractThe aims of the present study were as follows: (i) to perform the first 87Rb MRI in live rats with focal ischemic stroke; and (ii) to test the hypothesis that K+ egress from the brain in this model is quantifiable in individual animals by high‐field (7‐T) K/Rb substitution MRI. Rats preloaded with dietary Rb+ (resulting in Rb/(K + Rb) replacement ratios of 0.1–0.2 in the brain) were subjected to permanent occlusion of the middle cerebral artery, and 87Rb MRI was implemented with 13‐min temporal resolution using a dedicated RF coil and a spiral ultrashort‐TE sequence (TR/TE = 3/0.07 ms). The ischemic core was localized by apparent diffusion coefficient mapping, by microtubule‐associated protein‐2 immunohistochemistry and by changes in surface reflectivity. [K], [Na] and [Rb] were determined independently in the micropunched samples by post‐mortem flame photometry. Both techniques were generally in agreement in the nonischemic cortex; however, the MRI‐assessed [K+ + Rb+] drop in ischemic brain was less pronounced (average efflux rate of 4.8 ± 0.2 nEq/mm3/h versus 10 ± 1 nEq/mm3/h by flame photometry; p < 0.0001). The use of higher field gradients for better spatial resolution, and hence more accurate quantification, is suggested. Copyright © 2011 John Wiley & Sons, Ltd.
Jitter‐minimized reliability‐maximized management of networks
Authors: Sheikh Waseem , Ghafoor Arif 
Published: January 2011

AbstractWe propose a joint optimization network management framework for quality‐of‐service (QoS) routing with resource allocation. Our joint optimization framework provides a convenient way of maximizing the reliability or minimizing the jitter delay of paths. Data traffic is sensitive to droppage at buffers, while it can tolerate jitter delay. On the other hand, multimedia traffic can tolerate loss but it is very sensitive to jitter delay. Depending on the type of data, our scheme provides a convenient way of selecting the parameters which result in either reliability maximization or jitter minimization. We solve the optimization problem for a GPS network and provide the optimal solutions. We find the values of control parameters which control the type of optimization performed. We use our analytical results in a multi‐objective QoS routing algorithm. Finally, we provide insights into our optimization framework using simulations. Copyright © 2011 John Wiley & Sons, Ltd.
A generalized model of non‐linear viscoelasticity: numerical issues and applications
Authors: Buhan M. de , Frey P. 
Published: January 2011

AbstractIn this paper, we consider a non‐linear viscoelastic model with internal variable, thoroughly analyzed by Le Tallecit et al. (Comput. Methods Appl. Mech. Engrg 1993; 109:233–258). Our aim is to study here the implementation in three dimensions of a generalized version of this model. Computational results will be analyzed to validate our model on toy problems without geometric complexity, for which pseudo‐analytical solutions are known. At the end, we present a three‐dimensional numerical simulation on a mechanical device. Copyright © 2011 John Wiley & Sons, Ltd.
Inter‐ and intramolecular hydrogen bonds in polyamines: variable‐concentration1H‐NMR studies
Authors: Nudelman Norma Sbarbati , Alvaro Cecilia E. Silvana 
Published: January 2011

AbstractInter‐ and intramolecular hydrogen bonding play an important role in determining the arrangement, physical properties, and reactivity of a great diversity of structures in chemical and biological systems. Several aromatic nucleophilic substitutions (ANS) in nonpolar aprotic, (non‐HBD), solvents recently studied in our laboratory have demonstrated the importance of self‐association of amines by hydrogen‐bond interactions. In this paper, we describe1H‐NMR studies carried out at room temperature on bi‐ and polyfunctionalized amines, namely:N‐(3‐amino‐1‐propyl)morpholine (3‐APMo), histamine, 2‐guanidinobenzimidazole (2‐GB), 1,2‐diaminoethane (EDA), 3‐dimethylamino‐l‐propylamine (DMPA), and 1‐(2‐aminoethyl)piperidine (2‐AEPip). By1H‐NMR measurements of amine solutions at variable concentrations we have shown that 3‐APMo, histamine and 2‐GB are able to form a six‐membered ring byintramolecularhydrogen bonding, while EDA, DMPA, and 2‐AEPip form dimers byintermolecularhydrogen bonds. Likewise, variable concentration1H‐NMR studies allowed estimation of the corresponding equilibrium constants for the dimerization. These results are correlated with experimental kinetic results of ANS, confirming hereto the relevance of the “dimer mechanism” in reactions involving these amines. Copyright © 2011 John Wiley & Sons, Ltd.
Temperature effect on an N‐channel commercial VDMOSFET transistor
Authors: Abboud Nadine , Salame Chafic , Cuminal Yvan , Foucaran Alain , Hoffmann Alain 
Published: January 2011

AbstractHigh temperature effect on MOSFET devices was evaluated by exposing the silicon devices to a temperature value above the normal operating range in order to study the device behavior under extreme conditions. Measurements show an increasing in the saturation drain‐source current and the reverse drain‐source current with temperature while the transistor threshold voltage and the diffusion voltage of the integrated pn junction were decreased. The carrier's mobility shows an increasing with temperature while the drain‐source on‐resistance was decreased. Switching times are also investigated as function of temperature and important variations are obtained on the device turn‐on and turn‐off times. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Photo‐sensing devices using a‐Si based materials
Authors: Vieira Manuela , Fernandes Miguel , Louro Paula , Fantoni Alessandro , Vieira Manuel A. , Costa João , Barata Manuel 
Published: January 2011

AbstractAmorphous Si/SiC stacked photodiodes working as photonic devices are reviewed. Several applications (imagers, wavelength division demultiplexing devices and optical amplifiers) are proposed. In the imagers scans speeds up to 10 K lines per second were achieved without degradation in resolution. In the Wavelength Division Demultiplexing devices transmission rates are of the order of 4 kbit/s. Optical amplification occurs under steady state irradiation where the polychromatic mixture of different colors is higher than the sum of the individual monochromatic contributions. Electrical models are present to support the sensing methodologies. Experimental and simulated results show that the tandem devices act as charge transfer systems. They filter, amplify, store and transport the photogenerated carriers, keeping its memory (colour, intensity and bit rate) without adding any optical pre‐amplifier or optical filter as in the standard p‐i‐n cells. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Structures responsible for radiative and non‐radiative recombination activity of dislocations in silicon
Authors: Mchedlidze Teimuraz , Arguirov Tzanimir , Kononchuk Oleg , Trushin Maxim , Kittler Martin 
Published: January 2011

AbstractRegular dislocation networks (DN) formed by direct bonding of Si wafers actively participate in recombination of minority carriers. Besides nonradiative recombination (NRR), dislocation‐related luminescence (DRL), i.e. radiative recombination could be observed. We show that the type of recombination is defined by the type of the dislocations and the structure of the network. Screw dislocations are mostly DRL active, while NRR is mostly related to edge dislocations. Moreover, the DRL intensity strongly depends on the misalignment angle between the crystal orientations of both bonded wafers. There exists an optimal alignment between bonded Si wafers, for which the DRL intensity has a maximum. Such alignment could be used for dislocation based all‐Si light emitting devices in the future on‐chip optical communication components. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Temperature and directional dependences of the infrared dielectric function of free standing silicon nanowire
Authors: Kazan M. , Bruyant A. , Sedaghat Z. , Arnaud L. , Blaize S. , Royer P. 
Published: January 2011

AbstractAn approach to calculate the infrared dielectric function of semiconductor nanostructures is presented and applied to silicon (Si) nanowires (NW's). The phonon modes symmetries and frequencies are calculated by means of the elastic continuum medium theory. The modes strengths and damping are calculated from a model for lattice dynamics and perturbation theory. The data are used in anisotropic Lorentz oscillator model to generate the temperature and directional dependences of the infrared dielectric function of free standing Si NW's. Our results showed that in the direction perpendicular to the NW axis, the complex dielectric function is identical to that of bulk Si. However, along the NW axis, the infrared dielectric function is a strong function of the wavelength. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)