bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Contraceptives in three South‐East Asian Countries
Authors: Lun Kwok‐Chan 
Published: August 2010

AbstractUse of contraceptives by some selected characteristics was studied for married women in the reproductive age range (MWRA) in three south‐east Asian countries. The data were obtained from each country's national family planning/fertility survey conducted around the mid‐seventies. Only the gross relationship between each of the selected characteristics and contraceptive use was compared. The proportion of MWRA using contraceptives for Singapore was almost twice as high as the corresponding proportions for Peninsular Malaysia and Thailand. The pattern of contraceptive use was largely similar for Thailand and Malaysia but different from Singapore. The differences were largely attributed to the absence of a large rural population in Singapore, the apparently greater tendency of women in Singapore to use reversible contraceptive methods for birth spacing and the easier access by women to family planning information and services, particularly sterilisation, than in Peninsular Malaysia and Thailand.
Discrepancy of Endometrial Dating in Mid‐Luteal Phase of Hyperprolactinemic Women
Authors: Tamaya Teruhiko , Murakami Toshiki , Fujimoto Jiro , Abe Jun , Okada Hiroji 
Published: August 2010

AbstractThe relation between serum hormone levels, endometrial cellular steroid receptor levels and endometrial dating was evaluated in the mid‐luteal phase of normoprolactinemic and hyperprolactinemic women for a better understanding of luteal insufficiency and determination of the possible effect of prolactin on the endometrium. In 8 out of 17 luteal hyperprolactinemic patients (47%), the endometrium appeared out‐of‐phase although there was no difference in basal plasma steroid levels between normo‐ and hyper‐prolactinemic in‐phase endometria. Such out‐of‐phase endometria, however, showed significantly decreased estrogen receptor levels. These findings suggest that one of the causes of the endometrium phase discrepancy during the mid‐luteal phase may be the direct effect of prolactin on the endometrium or an indigenous disturbance of cellular steroid receptor synthesis.
Effects of Sex‐steroid Hormones on Growth and Hormone Receptor Levels of Human Uterine Leiomyosarcoma Cells in Vitro
Authors: Ishiwata Isamu , Ishiwata Chieko , Ishikawa Hiroshi 
Published: August 2010

AbstractThe effects of 17β‐estradiol and progesterone on SKN‐I cells (human uterine leiomyosarcoma cells) were studied for concentrations ranging from 1 pM to 100 μM in Vitro. 17β‐Estradiol enhanced cell proliferation at 1 μM or lower, but suppressed it at higher concentrations (>10 μM). On the other hand, progesterone did not affect the cells at lower than 0.1 μM, but suppressed their growth at higher than 1 μM. The cells showed degenerating morphological changes 24 hours after administration of higher than 10 μM of these hormones. In cells treated 4 days with 17μ‐estradiol (0.1 to 10 nM), basal progesterone receptor levels increased from 1.3 to 2.25 pM/mg DNA and these effects of 17β‐estradiol were suppressed by the antiestrogen tamoxifen at 1 μM.
Binding Sites for Prostaglandin F2α in Human Corpora Lutea
Authors: Tanaka Shoichi , Shimoya Yasuharu , Hamamatsu Miho , Hashimoto Masayoshi 
Published: August 2010

AbstractThe specific binding of 3H‐prostaglandin(PG)F2α to rough cell membrane fractions of human corpora lutea during the menstrual cycle was examined in detail.The specific binding of 3H‐PGF2α was dependent on both duration and temperature of incubation. At 37°C total binding was maximal after 60 min and then reached equilibrium.The presence of unlabeled PGE1, PGE2 and PGF1α had no effect on 3H‐PGF2α binding in the same rough cell membrane fractions and almost complete inhibition was seen at 7 times 10‐7M unlabeled PGF2α.The specific 3H‐PGF2α binding to all corpora lutea was biphasic. The number of binding sites and association constants were nearly stationary throughout the luteal phase.The concentrations of binding sites were 2 ˜ 47 and 80 ˜ 280 f moles/mg protein and the association constants were 11.0 ˜ 20.0 and 0.56 ˜ 1.20 times 1011 M‐1
Intravenous Gammaglobulin Therapy for Severe Infections Caused after Treatment for Malignant Tumors of the Female Genital Tract
Authors: Ito Haruhide , Tanaka Tadao , Kurashima Tomiyo , Ohoba Akio , Watanabe Hiroshi 
Published: August 2010

AbstractA pepsin‐treated gammaglobulin preparation was intravenously administered to nineteen patients who developed severe infections after treatment for malignant tumors of the female genital tract. Fourteen of the nineteen patients (73.7%) showed a good or fair response to the gammaglobulin preparation. This preparation was especially effective against urinary tract and retroperitoneal space infections and against E. coli, Enterobacter and Pseudomonas. Immunoglobulin‐G (IgG) continued to increase in good and fair responders until seven days after gammaglobulin treatment. IgG and the percentage of B cells in good responders increased in parallel, although the cause of this finding could not be fully elucidated. Adverse reactions to the gammaglobulin preparation were not observed in any patients.
Epidemiology of Preeclampsia and Eclampsia
Authors: Dhall Kamala 
Published: August 2010

AbstractThe epidemiological characteristics of 1107 cases of preeclampsia and eclampsia admitted to the Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh, India, have been analysed. The incidence of preeclampsia and eclampsia was found to be 10.2 and 0.6%, respectively, of all hospital deliveries. Nulliparous patients had a higher incidence than multiparous patients in all age groups. Lack of adequate antenatal supervision was a major factor in 83% of cases, largely due to the patient̂s ignorance, illiteracy and apathetic attitude. Nutritional deficiencies and weather changes did not appear to affect the incidence of toxaemia. Early diagnosis and appropriate hospital management of these cases has been emphasised.
Cervical Dilatation for Early Abortion (New Approach)
Authors: Manorama B. , Bhattacharaya Prabha , Pawade Surendra 
Published: August 2010

AbstractCervical dilatation prior to suction evacuation tried in 230 women seeking medical termination of pregnancy from 8 to 14 weeks of gestation. In 170 women, Dilex‐C and in 60 women laminaria tent was used. Only one tent of same size was inserted and kept in cervical canal for sixteen (Group‐A), twelve (Group‐B) and eight hours (Group‐C). Mean dilatation achieved in Dilex‐C and Laminaria tent in Group‐A was 10,06 mm and 10.48 mm., in GroupB it was 10.44 mm, and 11.05 mm and in Group‐C the same was 10.01 mm and 10.00 mm respectively which is very much comparable. Clinical trial of Dilex‐C showed high degree of patien's acceptance without any obvious cervical injury. None of the patients showed displacement, hour glass formation bending or breaking, nor difficulty in removal. On follow up study at the end of one month these cases clinically did not s0how any signs of pelvic, uterine or cervical infection.
Norethisterone Oenanthate as an Injectable Contraceptive in Two Treatment Schedules in Interval Subjects
Authors: Gulati Kamlesh , Mapa Manik K. , Gupta Amar Nath , Singh Padamjit M. , Devi P.K. 
Published: August 2010

AbstractThe efficacy, incidence of side effects and discontinuation were studied in fifty subjects who received intramuscular norethisterone oenanthate 200 mgm in two treatment schedules over a period 18 months. Subjects in Group A received the injection every 2 months during the study period whereas those in Group B received the injection at a 2 monthly interval for the first six months and every 3 months thereafter for 18 months. No pregnancy occurred in either group. Longer cycles and a higher incidence of amenorrhea were noted in the group B subjects. The bleeding pattern showed an increase in spotting episodes, in group A at the fourth injection, following which no apparent difference in the bleeding pattern was noted in the two groups. The discontinuation rate was 80% at the end of the study, 28% of the subjects having dropped out for amenorrhea, 16% for irregular bleeding and spotting and 6% for minor medical complaints.
Vaginal Reconstruction with a Sigmoid Loop in Pelvic Exenteration
Authors: Ng Heung‐Tat , Kan Yuen‐Yee , Chao Kaun‐Chong , Yuan Chiou‐Chung 
Published: August 2010

AbstractIn the past 15 years, 55 patients with recurrent or advanced cervical cancer underwent pelvic exenteration. Two of them had vaginal reconstruction with a sigmoid loop concomitantly performed at the time of surgery. This procedure is particularly advantageous as: (1) it is possible to fill up the pelvic cavity denuded by the exenteration to prevent intestinal herniation, (2) it restores the vaginal function, (3) it makes the pelvic examination possible following total exenteration in which the anus and vagina in the past were almost always excised and obliterated.
Uterine Malignancies Developing after a Long Term Use of lUCD's
Authors: Hsu Chien‐Tien , Roan Cheng‐Hsiung , Chang Han‐Tong , Chen Shin‐Zon , Lin Yun‐Nan , Chen Tin‐Yao 
Published: August 2010

AbstractFour cases of uterine malignancies developed after use of IUCD's: 3 cases after a long term use and one case after a short time use. In Case 1, sarcoma developed 20 years after application at the exact site where the IUCD (nylon ring) was placed and well corresponded to the size and shape of the IUCD and had also invaded the myometrium. Local chronic irritation as a causative factor is strongly suggestive. In Cases 2 and 3, endometrial cancer developed 13 and 14 years after the application of a Lippes loop. It seems injudicious to interpret the occurrence solely as an accidental coincidence. Loops after prolonged use could have played some role in the development of the endometrial cancer. In the fourth case endometrial cancer developed 3 months after the placing of a nylon ring in the uterus at the time of tuboplasty to permit easy extraction of the polyethylene tube which was inserted through the fallopian tube. In this case, in view of her age, it is possible that preexisting endometrial hyperplasia with undetected precancerous lesions might have been present when the polyethylene tube and nylon ring were inserted and subsequently evolved into malignancy. The authors emphasize the importance of awareness of malignancy in prolonged vaginal bleeding in IUCD users, and consider a short term and interrupted use of IUCD's safer and advisable, although any cause and effect relationship between IUCD and uterine malignancy is still a matter of pure conjecture.
Relationship between Prostaglandin F and Steroids in Human Peripheral Venous Plasma and Concentration of Prostaglandin F in Corpus Luteum
Authors: Tanaka Shoichi , Hata Hiroshi , Shimoya Yasuharu , Yamamoto Hiroshi , Yamamoto Hiroshi , Hashimoto Masayoshi 
Published: August 2010

AbstractConcentrations of prostaglandin F and steroids in plasma and in corpus luteum (CL) were studied by radioimmunoassay during the luteal phase of the menstrual cycle in thirteen normal women.The average concentration of PGF in corpus luteum was 4.19 ± 1.59 ng/g (mean ± SE) (ranging from 0.03 to 20.5 ng/g) and in plasma was 208.1 ± 34.7 pg/ml (ranging from 47.0 to 393.3 pg/ml). There was no correlation between the concentrations of PGF in plasma and in CL.The average concentrations of progesterone and estradiol in plasma were 17.6 ± 1.2 ng/ml and 181.7 ± 20.7 pg/ml, respectively. These was no correlation between the plasma concentrations of PGF and steroids.There was a significant increase (p>0.01) in the mean concentration of PGF from the follicular phase (199.5 ± 26.4 pg/ml, n=35) to the luteal phase (241.9 ± 12.9 pg/ml, n=44).These findings are discussed in relation to the possible role of prostaglandin F in corpus luteum regression.
Danazol (an Antigonadotropin) in the Treatment of Catamenial Pneumothorax
Authors: Uemura Tsuguo , JVIatsuyama Akemi , Minaguchi Hiroshi , Ikeda Hirotada 
Published: August 2010

AbstractTwo cases of catamenial pneumothorax treated with danazol, an isoxazole derivative of 17α‐ethinyl testosterone, are reported. The first patient, a 44‐year‐old woman who had had 31 attacks of spontaneous pneumothorax at the onset of menstruation in the past 7 years, was given 400 mg danazol daily for 6 months. Episodes did not reoccur during the treatment or for 5 months after the treatment, though ovulation was observed in the first menstrual cycle after the treatment. The second patient was a 33‐year‐old woman who had had recurrent right‐sided chest pains related to the onset of menses. The endometrial implants in the diaphragm were excised but a right pneumothorax recurred at the first menstrual period after operation. After 4 months of therapy with danazol she has been asymptomatic for 20 months. Danazol therapy seems to be more effective on this disease and to have less side effects than other ovulation inhibiting drugs.
A Comparative Study on the NAD Glycohydrolase of the Maternal and Neonatal Erythrocytes
Authors: Suh Byung Hee , Lee Jae Hyun , Cho Yong Ho 
Published: August 2010

AbstractThe subcellular localization of NADase in the ghost fraction (96%) of neonatal erythrocytes was localized more than in the maternal ghost fraction (83%). The inhibition by free nicotinamide of hydrolytic activity of NADase was found to be greater (approximately twice) in the neonatal erythrocytes than in the maternal erythrocytes. The activatory effect was exerted on the both maternal and neonatal ghost‐NADase by the addition of lower concentration (less than 0.6 M) of urea. The membraneous protein of erythrocytes was fractionated into 5 bands namely, band I, II, III, IV, V and VI in the case of maternal erythrocytes in good contrast of 7 bands for the neonatal erythrocytes namely, I, II, III, IV, V, VI and VII. From these results, it was suggested that there is a definite difference between membraneous protein of maternal and neonatal erythrocytes and NAD glycohydrolase activity and it is reasoned to be due to the independent erythropoietic site for two individuals. The erythrocytes NAD glycohydrolase might be one of the isozyme which change their properties during developmental maturation. The possible functions of erythrocytes NAD glycohydrolase were also discussed with regard to erythrocytes maturation in hematopoietic system.
Uterine Malignancy Developing After a Long Term Use of IUCD Additional Report of a Case: Association of Endometrial Stromal Sarcoma with IUCD
Authors: Yang Li‐Chuan , Hsu Mei‐Lien , Jong Hong‐Lin , Wu Chii‐Ming , Lin Yun‐Nan , Chang Chung‐Chuan , Hsu Chien‐Tien 
Published: August 2010

AbstractA case of endometrial stromal sarcoma associated with the use of an IUCD is to be added to our previous report which included 4 cases of uterine malignancies developing after long‐term use of IUCD. In the present case, the IUCD (Lippes loop and nylon ring) had been used for 6 years with interruptions of 1–6 months. When the IUCD is associated with irregular bleeding, it is important to emphasize that besides irregular bleeding as a complication of IUCD, abortion, ectopic pregnancies and uterine malignancies should also be taken into consideration. Endometrial stromal sarcoma is a very rare uterine malignancy, therefore, the association of this tumor with IUCD must count as a great rarity. A case of this kind has never before appeared in the literature.
Hysterosalpingography 1. The Incidence of Tubal Spasm During Hysterosalpingography
Authors: Anandakumar C. , Rauff Mary , Wong Eric , Wong P.C. , MBBS SS Ratnam 
Published: August 2010

AbstractThe main objective of this study was to assess the frequency of tubal spasm during hysterosalpingography. 19 patients were subjected to hysterosalpingogram in whom no pelvic pathology was detected in laparoscopic hydrotubation. Six of these patients in whom both tubes were found to be patient on laparoscopic hydrotubation showed varying degrees of tubal blockage on hysterosalpingography. The incidence of tubal spasm as a cause of tubal blockage was 32%.
A Clinico–Pathological Diagnosis of Hypertensive Disorders of Pregnancy
Authors: Dhall Kamala , Dhall Gian I. , Chugh Kirpal S. , Dutta Brajendera N. 
Published: August 2010

AbstractClinico‐pathological correlation was carried out in 25 and 65 cases of normal and hypertensive disorders of pregnancy respectively. It was observed that blood urea levels were elevated in the presence of severe glomerular lesion and serum uric acid levels had direct correlation with the magnitude of the glomerular change as well as the clinical severity of the disease. Renal histology in toxaemia when viewed by light microscopy is placed in the non‐specific category of acute membranous glomerulo nephritis and does not help much to differentiate the hypertensive disorders of pregnancy from each other. The clinical diagnosis of preeclamptic toxaemia (PET) was misleading in 21.4% of multi‐gravidae and 5.2% of primigravidae. It was felt that clinical presentation of the individual case, her previous history coupled with renal function test give the maximum help in arriving at the diagnosis.
Ultrasonographic Identification of Polycystic Ovary
Authors: Matsunaga Isao , Hata Toshiyuki , Kitao Manabu 
Published: August 2010

AbstractEleven patients with clinical findings of suspected polycystic ovary syndrome (PCOS) were examined using real‐time ultrasound. The ovarian area of PCOS (average value 488 ± 183 mm2) was larger than that of patients without PCOS (average value 184 ± 66 mm2) (P>0.001). Ovarian structures in those with PCOS were evident in the form of peripheral or general cystic patterns on the ultrasonograms. Ultrasonography proved to be a pertinent diagnostic tool for a non‐invasive diagnosis of PCOS.
Choriocarcinoma Coexisting with Adenocarcinoma in the Pars Interstitialis of the Oviduct:A Case Report
Authors: Takagi Minoru , Sato Yasuro , Cho Renchu , Koh Kabu , Nagayama Takahisa 
Published: August 2010

SynopsisDouble cancer, especially choriocarcinoma and adenocarcinoma, is rarely seen. Choriocarcinoma coexisting with adenocarcinoma in the interstitial part of the oviduct was found in a 45‐year‐old Japanese woman. She was initially treated for ectopic pregnancy. On the 16th postoperative day, however, she suddenly fell into a comatose state and died from a brain hemorrhage caused by metastasis of the choriocarcinoma.This is the first reported case of a rare combination of these two carcinomas.
A New in vitro Assay System for Prolactin‐Releasing Activity and its Application for Demonstration of Porcine Hypothalamic Prolactin‐Releasing Factor (PRF)
Authors: Nomura Mitsuo , Miyamoto Kaoru , Hasegawa Yoshihisa , Ibuki Yoshito , Igarashi Masao 
Published: August 2010

AbstractA new sensitive and reproducible assay system for prolactin‐releasing activity (PRA) using a rat pituitary cell culture system was established. After pretreatment with bromocriptine (1.3 times 10‐7 M) in culture medium for 24 hr on the 4th day in culture, the 6 hr addition of thyrotropin releasing hormone (TRH) to culture medium increased prolactin secretion in a dose‐dependent manner at concentrations of TRH ranging from 3.2 times 10‐11 M to 2.0 times 10‐9 M; maximal prolactin response was 270% of the control value.By using this new assay system for PRA, prolactin‐releasing factor (PRF) in porcine hypothalami was isolated and identified. On Sephadex G‐25 gel‐chromatography of acid extracts of porcine hypothalami, PRA was found in the small peptide portion. These fractions of PRA were further subjected to CM‐cellulose (CM‐52) ion exchange chromatography, followed by reverse‐phase HPLC. PRA obtained by HPLC chromatography was neutralized by anti‐TRH antibody. It was concluded that TRH is the main PRF in porcine hypothalamic extracts.
Midtrimester Artificial Abortion Using 16, 16‐dimeth‐l‐trans‐Δ2‐PGE1 meth‐l ester (Preglandin®), Laminaria Tents and Continuous Epidural Anesthesia
Authors: Fuchi Isao , Noda Kiichiro 
Published: August 2010

SummaryFor this stud‐, Preglandin (16, 16 dimeth‐l trans‐Δ2‐PGE1 meth‐l ester) was used for midtrimester artificial abortion. The methodolog‐, however, differed from that described in other reports. Our present method includes first inserting laminaria tents to dilate the cervix and administering albumin tannate to prevent side effects. We then insert PGEj vaginal suppositories to induce artificial abortion and use epidural anesthesia to relieve pain.A total of 19 patients were used for this stud‐. In 15 patients, the abortion was performable before 5 or less PGE1 vaginal suppositories had been used. The remaining 4 patients did not reach this stage until after intravenous drip PGF2α had been administered the following da‐. PGE1 is simple to use and appears to be effective in midtrimester artificial abortion if attention is given to the possibilit‐ of bag rupture, which ma‐ occur during the earl‐ stage of the treatment.
The Relation of Pregnanc‐ Associated Plasma Protein A (PAPP‐A) in the Umbilical Circulation of the Human Fetus to Oestriol Production b‐ the Placenta
Authors: Grudzinskas J. G. , Obiekwe B. C. , Perry L. A. , Houghton D. J. , Sinosich M. J. , Bolton A. E. , Chard T. 
Published: August 2010

AbstractLevels of pregnanc‐associated plasma protein A (PAPP‐A), alphafetoprotein (AFP), unconjugated oestriol (E3) and placental lactogen (hPL) were measured in maternal peripheral and umbilical cord arterial and venous blood obtained from 29 normal pregnancies at term deliver‐. PAPP‐A levels were three orders of magnitude higher in the mother than the fetus. Levels were higher in the umbilical arter‐ than the umbilical vein though this was not statisticall‐ significant. There was a close correlation between maternal and fetal levels of E3. There was no direct correlation between: (i) umbilical and maternal PAPP‐A levels; (ii) maternal PAPP‐A and E3 levels; or (iii) umbilical PAPP‐A and E3 levels. There was a significant inverse relationship between fetal PAPP‐A levels and the umbilical venoarterial difference of E3. No such relationship was found with fetal levels of AFP or hPL. These findings suggest a close functional association between PAPP‐A and the placental s‐nthesis of oestrogens.
Mixed Mesodermal Tumor of the Uterine Cervix ‐A Trial Search for Intermediate Forms between Carcinoma and Sarcoma ‐
Authors: Tokunaga Tatsu‐a , Matsu‐ama Shigemaro , Kuwahara Shozaburo , Himeno R‐uichi , Terao Kiminari 
Published: August 2010

AbstractMixed mesodermal tumor of the uterus are not uncommon; however, their histogenesis has remained unsolved.A case of endocervical mixed mesodermal tumor consisting of a well‐differentiated squamous carcinoma and a rhabdom‐osarcoma was studied histologicall‐. The sections were stained b‐ specific keratin staining methods, Martinotti's keratin staining and the peroxidase‐antibod‐ method, as well as b‐ the usual histologic stainings. The specific stainirigs revealed keratin‐like substances within the c‐toplasm of the squamous cartinoma cells and also that of a few sarcomatous cells scattered in the area of the sarcoma. These cells, which were functionall‐ epithelial and morphologicall‐ non‐epithelial, seemed to be intermediate forms between carcinoma and sarcoma.This finding suggested that the carcinomatous lesion might have undergone transformation into the sarcomatous one. The authors therefore believe that mixed mesodermal tumor originates from a single strain of endometrial or endocervical cells.