bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expansive Focal Cemento-Osseous Dysplasia
Authors: Bulut Emel Uzun , Acikgoz Aydan , Ozan Bora , Zengin Ayse Zeynep , Gunhan Omer 
Published: May 2012

ABSTRACT

Aim
To present a case of expansive focal cemento-osseous dysplasia and emphasize the importance of differential diagnosis.

Background
Cemento-osseous dysplasia is categorized into three subtypes on the basis of the clinical and radiographic features: Periapical, focal and florid. The focal type exhibits a single site of involvement in any tooth-bearing or edentulous area of the jaws. These lesions are usually asymptomatic; therefore, they are frequently diagnosed incidentally during routine radiographic examinations. Lesions are usually benign, show limited growth, and do not require further surgical intervention, but periodic follow-up is recommended because occasionally, this type of dysplasia progresses into florid osseous dysplasia and simple bone cysts are formed.

Case report
A 24-year-old female patient was referred to our clinic for swelling in the left edentulous mandibular premolarmolar region and felt discomfort when she wore her prosthetics. She had no pain, tenderness or paresthesia. Clinical examination showed that the swelling in the posterior mandible that was firm, nonfluctuant and covered by normal mucosa. On panoramic radiography and computed tomography, a welldefined lesion of approximately 1.5 cm in diameter of mixed density was observed.
The swelling increased slightly in size over 2 years making it difficult to use prosthetics and, therefore, the lesion was totally excised under local anesthesia, and surgical specimens were submitted for histopathological examination. The histopathological diagnosis was focal cemento-osseous dysplasia.

Conclusion
In the present case, because of the increasing size of the swelling making it difficult to use prosthetics, young age of the patient and localization of the lesion, in the initial examination, cemento-ossifying fibroma was suspected, and the lesion was excised surgically; the histopathological diagnosis confirmed it as focal cemento-osseous dysplasia.

Clinical significance
We present a case of expansive focal cemento-osseous dysplasia. Differential diagnosis is essential because ossifying fibroma is a real neoplastic entity.

How to cite this article
Uzun Bulut E, Acikgoz A, Ozan B, Zengin AZ, Gunhan O. Expansive Focal Cemento-Osseous Dysplasia. J Contemp Dent Pract 2012;13(1):115-118.
Single Visit Replacement of Maxillary Canine using Fiber-reinforced Composite Resin
Authors: Garoushi Sufyan , Lassila Lippo , Vallittu Pekka K 
Published: May 2012

ABSTRACT
Missing a canine is of serious concern in social life of a patient in most of societies. While conventional fixed partial dentures and implant-supported restorations may often be the treatment of choice, fiber-reinforced composite (FRC) resins offer a conservative, fast and cost-effective alternative for single and multiple teeth replacement. This clinical report presents two cases where FRC technology was successfully used to restore canine edentulous area in terms of esthetic-cosmetic values and functionality.

How to cite this article
Garoushi S, Lassila L, Vallittu PK. Single Visit Replacement of Maxillary Canine using Fiber-reinforced Composite Resin. J Contemp Dent Pract 2012;13(1):125-129.
Endodontic Management of Maxillary Supplementary Premolar using Cone-Beam Computed Tomography
Authors: Vora Jugal , Meena N , Mehta Deepak , Murthy Chethana S 
Published: May 2012

ABSTRACT
Extra teeth in dentition is termed as ‘supernumerary teeth’ and is a very well-known dental developmental anomaly. Supernumerary premolars are a rare anomaly in the maxillofacial complex. Its rarity and complex characteristics often makes it difficult to treat. Radiographs play an important role in assessment of both the location and the typing of supernumerary teeth.
This article reports the rare case of ‘nonsyndromic bilateral maxillary supernumerary premolars’ in which the endodontic management of supernumerary premolar tooth is described. In this case the value of cone-beam computerized tomography is also emphasized.

Clinical significance
Developmental anomalies can occur in any tooth and supplementary premolars are no exception. The complexity of such teeth has to be considered for planning endodontic treatment to increase the chances of success.

How to cite this article
Vora J, Meena N, Mehta D, Murthy CS. Endodontic Management of Maxillary Supplementary Premolar using Cone-Beam Computed Tomography. J Contemp Dent Pract 2012;13(1):130-135.
Conventional but not High-Purity Dialysis Fluid Induces Apoptosis and Insulin Resistance in Adipocytes in Vitro
Authors: Cai Ling L. , Pan Yu , Guo Li L. , Zhu Xiao J. , Gao Feng H. , Tan Long Y , Xu Qin J. , Jin Hui M. 
Published: May 2012

Purpose: Previous study has shown an independent association of low body fat percentage and fat loss over time with higher mortality in hemodialysis (HD) patients. High-purity dialysis fluid (HPDF) used in place of conventional dialysis fluid (CDF) may decrease inflammation and improve nutritional status. Its effect on adipocytes and therefore fat storage is unclear. The purpose of this study was to assess the effects of these dialysates on apoptosis and insulin resistance in cultured adipocytes to determine a basis for the superiority of HPDF. Methods: Flow cytometry and fluorescence staining were used to evaluate apoptosis in adipocytes. Insulin receptor substrate-1 (IRS-1) and −2 and serine phosphorylation of IRS-1 levels were assayed by Western blot. Tumor necrosis factor α (TNFα) levels were measured by enzyme-linked immunosorbent assay (ELISA). Results: Although CDF contained more bacteria (66 ± 6 CFU/mL) than HPDF (7 ± 3 CFU/mL) and higher levels of bacterial DNA, endotoxin levels were similar. Combined with uremic serum (containing high TNFα levels), CDF (vs. HPDF) induced more apoptosis in adipocytes. Exposure to CDF also decreased expression of IRS-1 protein, increased expression of IRS-2 protein and insulin-stimulated serine phosphorylation of IRS-1, and decreased glucose consumption. Additionally, the culture supernatant from adipocytes exposed to CDF plus uremic serum for 48 hours contained significantly higher levels of TNFα (15.17 ± 2.89 vs. 8.12 ± 0.54 pg/mL [HPD plus uremic serum], p<0.0001). Conclusion: The advantage of HPDF over CDF may be due to lower levels of dialysis fluid impurities.
Outcome of Patients with Amyloidosis after Renal Transplantation: A Single-Center Experience
Authors: Gursu Meltem , Yelken Berna , Caliskan Yasar , Kazancioglu Rumeyza , Yazici Halil , Kilicaslan Isin , Turkmen Aydin , Sever Mehmet S. 
Published: May 2012

Aims: The prognostic outcome of patients with amyloidosis who receive a kidney transplant is controversial. The aim of the study was to analyze the renal transplantation outcome of patients with amyloidosis compared to transplant recipients with other kidney diseases. Methods: Among 940 patients who had renal transplantation in our unit between 1983 and 2009, 44 patients with amyloidosis were compared regarding early and late complications and survival, retrospectively, with a control group of 41 consecutive patients with the same donor type and a matched renal transplantation date. Results: The groups were similar regarding demographic parameters, HLA mismatch numbers and mean follow-up period. Groups were similar regarding early and late infectious and non-infectious complications, except recurrence of the primary disease, which was more common in the amyloidosis group. As the cause of graft loss, rejection (acute or chronic) was more common in the control group; whereas primary non-functioning graft, and death with a functioning graft were more common in the amyloidosis group. Patient survival rates at 1, 5, and 10 years were 87.6%, 78.1%, and 62.3 in the amyloidosis group; and 93.2%, 82.6%, and 69.3% in the control group. Graft survival rates at 1, 5 and 10 years were 87.6%, 75.4%, 56.4% in the amyloidosis group; and 93.2%, 80.3%, and 60.6% in the control group, respectively. These values did not show any statistical difference. Conclusions: The outcomes of renal transplantation in patients with amyloidosis are comparable with recipients whose primary problems are due to other kidney diseases; therefore, amyloidosis patients should be accepted as good candidates for transplantation.
Ferroelectric Control of Spin‐Orbitronics
Authors: Gu Youdi , Zheng Zhenyi , Jia Lanxin , Shi Shu , Zhao Tieyang , Zeng Tao , Zhang Qihan , Zhu Yao , Wang Han , Chen Jingsheng 
Published: June 2024

AbstractSpin‐orbit coupling refers to the relativistic interaction between the spin and orbital motions of electrons. This interaction leads to numerous intriguing phenomena, including spin‐orbit torques, spin–momentum locking, topological spin textures, etc., that have recently gained prominence in the field of spin‐orbitronics. In particular, the emerging ferroelectric control is recognized and validated as an effective means to enhance energy efficiency across a broad spectrum of spin‐orbitronic devices. Here, cutting‐edge research on ferroelectric control of spin‐orbitronics (FECSO) by means of spontaneous polarization, reversible ferroelectric switching, and multiferroic coupling, are comprehensively reviewed. Two fascinating topics are mainly discussed: topological spin texture and spin‐charge interconversion. The classification of control mechanisms for different interactions in FECSO is summarized first. Then, from the perspective of material classification, the ferroelectric‐controlled spin‐orbit coupling with tunable topological spin texture in oxide systems, magnetic metal multilayers, and 2D van der Waals materials is reviewed. Subsequently, the ferroelectric‐tunable spin‐charge interconversion on heavy metal layers, oxide interfaces, and ferroelectric Rashba semiconductors is highlighted. In the end, the challenges and forthcoming prospects of FECSO are discussed. This work may provide pertinent and forward‐thinking guidance to accelerate the ongoing advancement of this field.
Polymersomal Poly(I:C) Self‐Magnifies Antitumor Immunity by Inducing Immunogenic Cell Death and Systemic Immune Activation
Authors: Wang Jingyi , Guo Beibei , Sun Zhiwei , Zhao Songsong , Cao Li , Zhong Zhiyuan , Meng Fenghua 
Published: June 2024

AbstractImmunotherapy has emerged as a powerful weapon against lung cancer, yet only a fraction of patients respond to the treatment. Poly(I:C) (PIC) effectively triggers both innate and adaptive immunity. It can also induce immunogenic cell death (ICD) in tumor cells. However, its efficacy is hindered by its instability in vivo and limited cellular uptake. To address this, PIC is encapsulated in cRGD‐functionalized polymersomes (t‐PPIC), which significantly increases its stability and uptake, thus activating dendritic cells (DCs) and inducing apoptosis of lung tumor cells in vitro. In a murine LLC lung tumor model, systemic administration of t‐PPIC effectively suppresses tumor growth and leads to survival benefits, with 40% of the mice becoming tumor‐free. Notably, t‐PPIC provokes stronger apoptosis and ICD in tumor tissue and elicits a more potent stimulation of DCs, recruitment of natural killer (NK) cells, and activation of CD8+ T cells, compared to free PIC and nontargeted PPIC controls. Furthermore, when combined with immune checkpoint inhibitors or radiotherapy, t‐PPIC amplifies the antitumor immune response, resulting in complete regression in 60% of the mice. These compelling findings underscore the potential of integrin‐targeted polymersomal PIC to enhance antitumor immunity by simultaneously inducing ICD and systemic immune activation.
Aqueous‐Aqueous Triboelectric Nanogenerators Empowered Multifunctional Wound Healing System with Intensified Current Output for Accelerating Infected Wound Repair
Authors: Wang Weijiang , Fu Chongyang , Du Yanfeng , Zheng Huiyuan , Zhang Yage , Song Yang , Sun Wentao , Wang Xiaoxiong , Ma Qingming 
Published: June 2024

AbstractTriboelectric nanogenerators (TENGs) have emerged as promising devices for generating self‐powered therapeutic electrical stimulation over multiple aspects of wound healing. However, the challenge of achieving full 100% contact in conventional TENGs presents a substantial hurdle in the quest for higher current output, which is crucial for further improving healing efficacy. Here, a novel multifunctional wound healing system is presented by integrating the aqueous‐aqueous triboelectric nanogenerators (A‐A TENGs) with a functionalized conductive hydrogel, aimed at advancing infected wound therapy. The A‐A TENGs are founded on a principle of 100% contact interface and efficient post‐contact separation of the immiscible interface within the aqueous two‐phase system (ATPS), enhancing charge transfer and subsequently increasing current performance. Leveraging this intensified current output, this system demonstrates efficient therapeutic efficacies over infected wounds both in vitro and in vivo, including stimulating fibroblast migration and proliferation, boosting angiogenesis, enhancing collagen deposition, eradicating bacteria, and reducing inflammatory cells. Moreover, the conductive hydrogel ensures the uniformity and integrity of the electric field covering the wound site, and exhibits multiple synergistic therapeutic effects. With the capability to realize accelerated wound healing, the developed “A‐A TENGs empowered multifunctional wound healing system” presenting an excellent prospect in clinical wound therapy.
Breathable Dual‐Mode Leather‐Like Nanotextile for Efficient Daytime Radiative Cooling and Heating
Authors: Cheng Ningbo , Wang Zhaohui , Lin Yanyan , Li Xueqin , Zhang Yufei , Ding Chengfeng , Wang Chao , Tan Jing , Sun Feifei , Wang Xianfeng , Yu Jianyong , Ding Bin 
Published: June 2024

AbstractIncorporating passive radiative cooling and heating into personal thermal management has attracted tremendous attention. However, most current thermal management materials are usually monofunctional with a narrow temperature regulation range, and lack breathability, softness, and stretchability, resulting in a poor wearer experience and limited application scenarios. Herein, a breathable dual‐mode leather‐like nanotextile (LNT) with asymmetrical wrinkle photonic microstructures and Janus wettability for highly efficient personal thermal management is developed via a one‐step electrospinning technique. The LNT is synthesized by self‐bonding a hydrophilic cooling layer with welding fiber networks onto a hydrophobic photothermal layer, constructing bilayer wrinkle structures that offer remarkable optical properties, a wetting gradient, and unique textures. The resultant LNT exhibits efficient cooling capacity (22.0 °C) and heating capacity (22.1 °C) under sunlight, expanding the thermal management zone (28.3 °C wider than typical textiles). Additionally, it possesses favorable breathability, softness, stretchability, and sweat‐wicking capability. Actual wearing tests demonstrate that the LNT can provide a comfortable microenvironment for the human body (1.6–8.0 °C cooler and 1.0–7.1 °C warmer than typical textiles) in changing weather conditions. Such a wearable dual‐mode LNT presents great potential for personal thermal comfort and opens up new possibilities for all‐weather smart clothing.
UV‐Permeable 3D Li Anodes for In Situ Fabrication of Interface‐Gapless Flexible Solid‐State Lithium Metal Batteries
Authors: Xie Chuan , Rong Mingming , Guo Qianyi , Wei Zhenyao , Chen Zijian , Huang Qiyao , Zheng Zijian 
Published: June 2024

AbstractFlexible solid‐state lithium metal batteries (SSLMBs) are highly desirable for future wearable electronics because of their high energy density and safety. However, flexible SSLMBs face serious challenges not only in regulating the Li plating/stripping behaviors but also in enabling the mechanical flexibility of the cell. Both challenges are largely associated with the interfacial gaps between the solid electrolytes and the electrodes. Here, a UV‐permeable and flexible composited Li metal anode (UVp‐Li), which possesses a unique light‐penetrating interwoven structure similar to textiles is reported. UVp‐Li allows one‐step bonding of the cathode, anode, and solid electrolyte via an in situ UV‐initiated polymerization method to achieve the gapless SSLMBs. The gapless structure not only effectively stabilizes the plating/stripping of Li metal during cycling, but also ensures the integrity of the cell during mechanical bending. UVp‐Li symmetric cell presents a stable cycling over 1000 h at 0.5 mA cm−2. LiFePO4||UVp‐Li full cells (areal capacity ranging from 0.5 to 3 mAh cm−2) show outstanding capacity retention of over 84% after 500 charge/discharge cycles at room temperature. Large pouch cells using high‐loading cathodes maintain stable electrochemical performance during 1000 times of dynamic bending.
Eco‐Friendly Solutions to Emerging Contaminants: Unveiling the Potential of Bioremediation in Tackling Microplastic Pollution in Water
Authors: Ihsanullah Ihsanullah , Khan Muhammad Tariq , Hossain Md Faysal , Bilal Muhammad , Ali Shah Izaz 
Published: June 2024

AbstractMicroplastics (MPs) are a class of emerging contaminants that have gained significant attention in recent years. The presence of MPs in the aquatic environment is reported to have serious potential environmental and health impacts. Therefore, it is essential to develop efficient and sustainable strategies for the remediation of MPs from the aqueous environment. Traditional techniques for the remediation of MPs from an aqueous environment have limitations, including high costs and the production of secondary pollutants. In this scenario, bioremediation offers several advantages and has emerged as a cost‐effective, eco‐friendly, and efficient strategy for the removal of MPs from water. This article critically reviews the recent progress in the applications of bioremediation for the removal of different MPs from water. The effects of key factors such as the characteristics of MPs, environmental conditions, and types of microorganisms on the removal of MPs are elaborated in detail. The underlying mechanisms involved in the removal of MPs by microorganisms are also discussed comprehensively. Major technological challenges are identified, and recommendations for future research are provided. Despite several challenges, bioremediation is a promising approach that can revolutionize the MP removal process if the major challenges are addressed.
A Novel tsRNA, m7G‐3′ tiRNA LysTTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation
Authors: Ying Xiaoling , Hu Wenyu , Huang Yapeng , Lv Yifan , Ji Ding , Chen Cong , Yang Baotong , Zhang Chengcheng , Liang Yaomin , Zhang Haiqing , Liu Mingrui , Yuan Gang , Wu Wenqi , Ji Weidong 
Published: June 2024

AbstractEmerging evidence indicates that transfer RNA (tRNA)‐derived small RNAs (tsRNAs), originated from tRNA with high abundance RNA modifications, play an important role in many complex physiological and pathological processes. However, the biological functions and regulatory mechanisms of modified tsRNAs in cancer remain poorly understood. Here, it is screened for and confirmed the presence of a novel m7G‐modified tsRNA, m7G‐3′‐tiRNA LysTTT (mtiRL), in a variety of chemical carcinogenesis models by combining small RNA sequencing with an m7G small RNA‐modified chip. Moreover, it is found that mtiRL, catalyzed by the tRNA m7G‐modifying enzyme mettl1, promotes bladder cancer (BC) malignancy in vitro and in vivo. Mechanistically, mtiRL is found to specifically bind the oncoprotein Annexin A2 (ANXA2) to promote its Tyr24 phosphorylation by enhancing the interactions between ANXA2 and Yes proto‐oncogene 1 (Yes1), leading to ANXA2 activation and increased p‐ANXA2‐Y24 nuclear localization in BC cells. Together, these findings define a critical role for mtiRL and suggest that targeting this novel m7G‐modified tsRNA can be an efficient way for to treat BC.
Optimizing Length Scalability of InGaZnO Thin‐Film Transistors through Lateral Carrier Profile Engineering and Negative ΔL Extension Structure
Authors: Kim Su Hyun , Kim Mingoo , Lee Ji Hwan , Kim Kihwan , Park Joon Seok , Lim Jun Hyung , Oh Saeroonter 
Published: June 2024

AbstractThe lateral carrier profile of amorphous indium gallium zinc oxide (IGZO) thin‐film transistors (TFTs) plays a significant role in determining the effective channel length (Leff) and length scalability even when the physical gate length (Lg) is the same. Especially, devices with high carrier concentration that have a high mobility of 14.54 cm2 V·s−1 suffer from severe short channel effects at Lg = 1 µm due to the reduced Leff. The current work proposes a systematic methodology for optimizing length scalability for a given Lg that involves engineering of the lateral carrier profile. Unique lateral carrier profiles are extracted using contour maps of ΔL and RSD as a function of carrier profile parameters, and they are validated by comparing the measured Leff, drain‐to‐source resistance, and current‐voltage characteristics with the results of simulations using the extracted carrier profiles. Further, to overcome the trade‐off between enhanced mobility and degraded VT roll‐off that occurs with increasing carrier concentration, an IGZO TFT with gate‐insulator shoulders is fabricated to structurally form negative ΔL and physically increase Leff, while also obtaining a high carrier concentration, ultimately achieving both optimal electrical performance, with mobility of 17.50 cm2 V·s−1, and complete control of the electrostatic integrity of the gate.
Surgical complications in combined rhinoplasty and endoscopic sinus surgery
Authors: Fereydooni Soraya , Green Allen , Wei Eric X. , Rossi‐Meyer Monica K. , Kandathil Cherian K. , Most Sam P. 
Published: June 2024

Key points
Complications in combined surgery are equivalent to ESS but are higher than rhinoplasty alone.
The most common complications are pneumonia, stroke, and epistaxis.
Rhinoplasty surgeries with graft use have a higher risk of complications.
Digital Light Processing to Afford High Resolution and Degradable CO2‐Derived Copolymer Elastomers
Authors: Poon Kam C. , Segal Maddison , Bahnick Alexander J. , Chan Yin Mei , Gao Chang , Becker Matthew L. , Williams Charlotte K. 
Published: June 2024

AbstractVat photopolymerization 3D printing has proven very successful for the rapid additive manufacturing (AM) of polymeric parts at high resolution. However, the range of materials that can be printed and their resulting properties remains narrow. Herein, we report the successful AM of a series of poly(carbonate‐b‐ester‐b‐carbonate) elastomers, derived from carbon dioxide and bio‐derived ϵ‐decalactone. By employing a highly active and selective Co(II)Mg(II) polymerization catalyst, an ABA triblock copolymer (Mn=6.3 kg mol−1, ÐM=1.26) was synthesized, formulated into resins which were 3D printed using digital light processing (DLP) and a thiol‐ene‐based crosslinking system. A series of elastomeric and degradable thermosets were produced, with varying thiol cross‐linker length and poly(ethylene glycol) content, to produce complex triply periodic geometries at high resolution. Thermomechanical characterization of the materials reveals printing‐induced microphase separation and tunable hydrophilicity. These findings highlight how utilizing DLP can produce sustainable materials from low molar mass polyols quickly and at high resolution. The 3D printing of these functional materials may help to expedite the production of sustainable plastics and elastomers with potential to replace conventional petrochemical‐based options.