bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH SHIFT KERJA TERHADAP KINERJA PEGAWAI DENGAN MOTIVASI SEBAGAI VARIABEL INTERVENING DI RUMAH SAKIT SITI AISYAH KOTA LUBUKLINGGAU
Authors: Hartono Budi , Tafdhi Ikhwanul , Sastrawinata Hendra 
Published: April 2024

Masalah pada penelitian ini adalah 1) Adakah pengaruh shift kinerja terhadap kerja pegawai di Rumah Sakit Siti Aisyah Kota Lubuklinggau?, 3) Adakah pengaruh shift kerja terhadap kinerja pegawai melalui motivasi sebagai Variabel Intervening di Rumah Sakit Siti Aisyah Kota Lubuklinggau?. Tujuan penelitian ini adalah 1) Untuk mengetahui pengaruh shift kerja terhadap kinerja pegawai di Rumah Sakit Siti Aisyah Kota Lubuklinggau. 22) Untuk mengetahui pengaruh shift kerja terhadap kinerja pegawai melalui motivasi sebagai Variabel Intervening di Rumah Sakit Siti Aisyah Kota Lubuklinggau. Jenis penelitian adalah kuantitatif. Pengambilan sampel menggunakan sampel jenuh yaitu sebanyak 57 orang. Pengumpulan data dilakukan dengan angket. Analisis data menggunakan uji moderast. Hasil penelitian adalah 1) Ada pengaruh shift kerja terhadap kinerja pegawai di Rumah Sakit Siti Aisyah Kota Lubuklinggau.. Dapat dilihat dari hasil perhitungan thitung sebesar 6,259 menunjukan nilai ttabel sebesar 2,057 sehingga dengan demikian bahwa thitung > ttabel. 2) Ada pengaruh shift kerja terhadap kinerja pegawai melalui motivasi sebagai Variabel Intervening di Rumah Sakit Siti Aisyah Kota Lubuklinggau sebesar 0,098 atau 9,8%.
Justifying Limitations on Freedom of Expression for Contempt of Religion
Authors: Waheduzzaman Moha 
Published: April 2024

In the recent past, there have been the cases of making abusive remarks against Prophet Muhammad, drawing cartoons of him, and burning the Holy Quran in public. These incidents no doubt outrage the religious feelings of people belonging to the religion of Islam. Besides this, they also contribute to violence and riot and the consequential deaths of people around the world. There are, however, literatures which seek to justify these conducts having a very liberal and extended view of the right to freedom of expression. They argue as if there should not be any limitation on freedom of expression so far that relates to contempt of any religion. I argue that freedom of expression howsoever valuable that might be, is a qualified as opposed to an unqualified human right. Hence, its exercise cannot extend to making abusive remarks against religious personages or defiling or burning the Holy Book(s) of any religion. If it is acknowledged by all including the relevant stakeholders of the United Nations, this might help reducing the chances of human casualties and deaths of people caused by alleged blasphemous conducts with respect to any religion. Foreseeing this significance, I aim to revisit the justification and limits of freedom of expression in the backdrop of contempt of religion.
Dhaka University Law Journal, 2023, 34 (2), 43-65
REsveratrol for VAscular cognitive impairment investigating cerebral Metabolism and Perfusion (REVAMP trial): a study protocol for a randomized, double-blind, placebo-controlled trial
Authors: Hattori Yorito , Minami Manabu , Omae Katsuhiro , Yoshimoto Takeshi , Abe Soichiro , Yamamoto Haruko , Iida Hidehiro , Ihara Masafumi 
Published: April 2024

BackgroundCarotid artery stenosis or occlusion (CASO) is a major cause of vascular cognitive impairment (VCI). There is currently no effective treatment for VCI induced by CASO. Resveratrol, a type of polyphenol, improves cognitive performance in rat CASO models via pleiotropic effects. Furthermore, we previously reported the longevity gene, SIRT1, which can be activated by resveratrol, improves cognitive and cerebral blood flow impairment in mouse CASO models by activating endothelial nitric oxide synthase. However, clinical evidence remains limited.MethodsThe REsveratrol for VAscular cognitive impairment investigating cerebral Metabolism and Perfusion (REVAMP) trial is a randomized, double-blind, placebo-controlled trial involving patients with asymptomatic CASO. Each participant will receive either 150 mg/day of resveratrol or a placebo for 35 weeks. The primary objective is to determine whether resveratrol improves cognitive impairment, as assessed using the Alzheimer’s disease Assessment Scale–cognitive subscale 13. One of our secondary objectives is to determine whether resveratrol improves cerebral hemodynamic impairment as assessed via 15O-gas positron emission tomography. We will recruit 100 patients (50 per group).DiscussionThe REVAMP trial may provide valuable insights into new therapeutic options, as multitarget neuroprotection could potentially improve cognitive function along with enhancements in cerebral hemodynamic status in patients with asymptomatic CASO.Clinical trial registration: The REVAMP trial was prospectively registered in the Japan Registry of Clinical Trials (jRCTs051230013) on April 13, 2023.
Salivary excretion of systemically injected [18F]DCFPyL in prostate cancer patients undergoing PSMA scans
Authors: Fernandes Bruna , Roy Jyoti , Basuli Falguni , Warner Blake M. , Lindenberg Liza , Mena Esther , Adler Steven S. , Griffiths Gary L. , Choyke Peter L. , Lin Frank I. 
Published: April 2024

IntroductionProstate-specific membrane antigen (PSMA) is present in high amounts in salivary glands, but it is unclear whether labeled binders of PSMA are excreted in the saliva.MethodsTen patients with prostate cancer underwent whole-body [18F]DCFPyL PET/CT (NCT03181867), and saliva samples were collected between 0-120 minutes post-injection. [18F]DCFPyL salivary excretion was measured over 120 minutes and expressed as %ID/g. Protein-associated binding was estimated by the percentage of [18F]DCFPyL versus parent radiotracer.ResultsAll PET scans of 10 patients (69 ± 8 years) with histologically confirmed prostate cancer (PSA= 2.4 ± 2.4, and Gleason Grade = 6-9) showed high uptake of [18F]-DCFPyL in salivary glands while 8 patients demonstrated high uptake in the saliva at 45 minutes. The intact [18F]-DCFPyL (98%) was also confirmed in the saliva samples at 120 min with increasing salivary radioactivity between 30-120 min.ConclusionSystemically injected [18F]DCFPyL shows salivary gland uptake, an increasing amount of which is secreted in saliva over time and is not maximized by 120 minutes post-injection. Although probably insignificant for diagnostic studies, patients undergoing PSMA-targeted therapies should be aware of radioactivity in saliva.
Cervical cancer prevention by vaccination: review
Authors: González-Rodríguez Julio Cesar , Cruz-Valdez Aurelio , Madrid-Marina Vicente 
Published: April 2024

AbstractRoutine use of human papillomavirus (HPV) vaccines is recommended in adolescents under 15 years of age worldwide. Still, effective programs remain suboptimal for several factors, making the WHO strategy to eradicate cervical cancer public health with an uncertain future.ObjectiveTo review the literature on the effectiveness, long-term protection, and safety of HPV vaccination programs and vaccination as adjuvant management. This review aims to describe the current state of vaccination programs and demonstrate the long-term protection and safety of vaccines implemented worldwide targeting adolescent girls, with the most recent published evidence of the three prophylactic HPV vaccines – bivalent (bHPV), quadrivalent (qHPV), and nonavalent (nHPV)-. We mainly focus on publications evaluating efficacy, dosing schemes, and HPV vaccination, as well as studies contributing to the mounting evidence for the real-life effectiveness of prophylactic HPV vaccines from several countries.FindingsHuman Papillomavirus vaccination programs have made remarkable strides in preventing HPV-related diseases; countries with robust vaccination efforts have witnessed substantial reductions in HPV-related diseases with a decline in high-grade cervical abnormalities and genital warts (54%-83%). However, global coverage remains uneven, with disparities between high-income (HICs) and low-income countries (LMICs). The long-term efficacy of the available human papillomavirus (HPV) goes up to 9.4 years and continues to be immunogenic and well tolerated with an excellent safety profile.Conclusions and relevanceAs these are crucial topics in HPV vaccination, it is essential to establish systems for continued monitoring of vaccine immunogenicity, efficacy, and safety over time.
Multimodal in-vivo maps as a tool to characterize retinal structural biomarkers for progression in adult-onset Stargardt disease
Authors: Pedersen Hilde R. , Gilson Stuart J. , Hagen Lene A. , Holtan Josephine Prener , Bragadottir Ragnheidur , Baraas Rigmor C. 
Published: April 2024

PurposeTo characterize retinal structural biomarkers for progression in adult-onset Stargardt disease from multimodal retinal imaging in-vivo maps.MethodsSeven adult patients (29–69 years; 3 males) with genetically-confirmed and clinically diagnosed adult-onset Stargardt disease and age-matched healthy controls were imaged with confocal and non-confocal Adaptive Optics Scanning Light Ophthalmoscopy (AOSLO), optical coherence tomography (OCT), fundus infrared (FIR), short wavelength-autofluorescence (FAF) and color fundus photography (CFP). Images from each modality were scaled for differences in lateral magnification before montages of AOSLO images were aligned with en-face FIR, FAF and OCT scans to explore changes in retinal structure across imaging modalities. Photoreceptors, retinal pigment epithelium (RPE) cells, flecks, and other retinal alterations in macular regions were identified, delineated, and correlated across imaging modalities. Retinal layer-thicknesses were extracted from segmented OCT images in areas of normal appearance on clinical imaging and intact outer retinal structure on OCT. Eccentricity dependency in cell density was compared with retinal thickness and outer retinal layer thickness, evaluated across patients, and compared with data from healthy controls.ResultsIn patients with Stargardt disease, alterations in retinal structure were visible in different image modalities depending on layer location and structural properties. The patients had highly variable foveal structure, associated with equally variable visual acuity (-0.02 to 0.98 logMAR). Cone and rod photoreceptors, as well as RPE-like structures in some areas, could be quantified on non-confocal split-detection AOSLO images. RPE cells were also visible on dark field AOSLO images close to the foveal center. Hypo-reflective gaps of non-waveguiding cones (dark cones) were seen on confocal AOSLO in regions with clinically normal CFP, FIR, FAF and OCT appearance and an intact cone inner segment mosaic in three patients.ConclusionDark cones were identified as a possible first sign of retinal disease progression in adult-onset Stargardt disease as these are observed in retinal locations with otherwise normal appearance and outer retinal thickness. This corroborates a previous report where dark cones were proposed as a first sign of progression in childhood-onset Stargardt disease. This also supports the hypothesis that, in Stargardt disease, photoreceptor degeneration occurs before RPE cell death.
Contribution of arbuscular mycorrhizal fungi to the bioavailability of micronutrients (iron and zinc) in millet accessions
Authors: Founoune-Mboup Hassna , Diallo Bassirou , Adigoun Rabiath Féichokpè Raïssa , Kane Aboubacry , Fall Abdoulaye Fofana 
Published: April 2024

IntroductionMicronutrient deficiencies, particularly iron (Fe) and zinc (Zn) deficiencies, are prevalent public health issues in developing countries, with children under 5 years old and breastfeeding women being the most affected in Senegal. Agronomic approaches, including soil fertilization and microbial biotechnology, are used to alleviate these deficiencies, yet challenges persist due to poor nutrient availability in staple food crops like pearl millet (Pennisetum glaucum L.).MethodsThis study aimed to assess the contribution of one arbuscular mycorrhizal fungal (AMF) strain, Glomus mosseae, to the bioavailability of micronutrients (zinc and iron) in pearl millet biomass. Four pearl millet accessions from the National Laboratory for Research on Plant Production (LNRPV) collection were inoculated with G. mosseae obtained from the Common Microbiology Laboratory (LCM), with four replications. Gaussian regression tests were employed to analyze the data and determine correlations between AMF concentration and micronutrient bioavailability.ResultsThe results indicate that the combination of Glomus mosseae inoculation and organic residual products improved growth parameters and micronutrient absorption in pearl millet accessions. Analysis revealed significantly greater iron, zinc, phosphorus, and potassium contents in the foliar biomass of mycorrhizal pearl millet plants compared to non-mycorrhizal plants (control). Inoculation with AMF facilitated micronutrient absorption, particularly iron and zinc, not only in roots but also in aerial parts of the plants.DiscussionThese findings suggest that incorporating AMF and organic residual products in millet cultivation could be a viable strategy for enhancing plant development and increasing iron and zinc contents in varieties. Further research is needed to elucidate the mechanisms underlying AMF-mediated nutrient uptake and optimize their use in agricultural practices.
Understanding and tackling meat reduction in different cultural contexts: a segmentation study of Swiss and Vietnamese consumers
Authors: Delley Mathilde , Ha Thanh Mai , Götze Franziska , Markoni Evelyn , Ngo Minh Hai , Nguyen Anh Duc , Bui Thi Lam , Le Nhu Thinh , Pham Bao Duong , Brunner Thomas A. 
Published: April 2024

ObjectiveThis study aims to disclose and compare meat consumer segments in Switzerland and Vietnam, which differ in terms of their socioeconomic and cultural settings (the former is a developed country, and the latter is an emerging one) to develop a set of segment-specific recommendations that might be applied to consumption in comparable contexts, that is, in other developed countries and other emerging economies.MethodsData were collected through two online surveys: one for Swiss residents from randomly selected households and one for Vietnamese urban residents recruited via snowball sampling. The final sample size was N = 643 for Switzerland and N = 616 for Vietnam. Hierarchical cluster analyses followed by K-means cluster analyses revealed five distinct clusters in both countries.ResultsThree clusters were common to both countries: meat lovers (21% in Switzerland and 19% in Vietnam), proactive consumers (22% in Switzerland and 14% in Vietnam) and suggestible consumers (19% in Switzerland and 25% in Vietnam). Two were specific to each country, namely traditional (19%) and basic (21%) consumers in Switzerland and confident (16%) and anxious (26%) consumers in Vietnam.ConclusionRelying on voluntary actions, nudging techniques, private initiatives and consumers’ sense of responsibility will certainly be useful but will nevertheless be insufficient to achieve a planetary health diet within the given timeframe (the 2030 Agenda for Sustainable Development). Governments will have no choice but to activate all levers within their sphere of influence – including regulatory measures – and oblige private sector actors to commit to the measures imposed on them. A binding international agenda with common objectives and measures is a judicious approach. Unlike most previous studies, which focused on meat consumption intensity and frequency or diet type to segment consumers, our approach, based on psychographic profiles, allows the identification of segments that share common drivers and barriers and thus the development of better-targeted measures to reduce meat consumption.
Relationships between erythrocyte membrane mono- and poly- unsaturated fatty acid composition and clinical/cognitive indices in antipsychotic-free schizophrenia patients
Authors: Higuchi Yuko , Takahashi Tsutomu , Itoh Hiroko , Sasabayashi Daiki , Sumiyoshi Tomiki , Suzuki Michio 
Published: April 2024

IntroductionMembrane phospholipid abnormalities are considered a pathophysiological background for schizophrenia. The aim of the study was to explore in detail the fatty acid (FA) composition in patients with antipsychotic-free schizophrenia and its association with clinical symptoms and cognitive function.Materials and methodsErythrocyte membrane FAs were measured in 29 antipsychotic-free patients with schizophrenia (male/female = 11/18; mean [standard deviation] age=26.7 [7.9] years) and age and sex-matched 32 healthy volunteers. Clinical symptoms and cognitive function were assessed using the Positive and Negative Syndrome Scale (PANSS), Brief Assessment of Cognition in Schizophrenia (BACS), and the Schizophrenia Cognition Rating Scale (SCoRS).ResultsEicosapentaenoic acid levels were lower in the schizophrenia group than in the healthy control group. In contrast, arachidonic acid and nervonic acid levels were higher in the schizophrenia group than in the control group. Nervonic acid levels were significantly associated with depression scores as measured by the PANSS. No FA levels were correlated with BACS score; however, oleic acid levels were significantly related to cognitive dysfunction, as measured by the SCoRS.ConclusionThese findings suggest that depressive symptoms along with cognitive dysfunction in daily living in schizophrenia may be linked to the FA composition abnormalities. Further studies will be needed to examine potential longitudinal FA changes during the course of schizophrenia as well as disease specificity.
Prevalence of work-related burnout and associated factors among police officers in central Gondar zone, Northwest Ethiopia, 2023
Authors: Bezie Anmut Endalkachew , Getachew Yenealem Dawit , Asega Belay Azanaw , Bitew Abie Alebachew , Abebaw Tadiwos , Melaku Christian , Mamaye Yimer , Hailu Tesfaye Amensisa 
Published: April 2024

IntroductionWork-related burnout is a state of physical and psychological fatigue and exhaustion resulting from chronic workplace stress related to work. The police workforce is vulnerable to this psychosocial hazard, which affects service delivery by police workers. However, there is little evidence about the prevalence of work-related burnout and associated factors among police officers in Ethiopia. Therefore, this research investigated the prevalence and predictor variables of work-related burnout among police officers in central Gondar zone, Northwest Ethiopia, 2023.MethodsAn institution-based cross-sectional study was carried out from April 12 to May 12, 2023. A sample of 633 police officers was recruited through multistage random sampling techniques. To measure work-related burnout, a standardized, self-administered Copenhagen Burnout Inventory was used. To enter the collected data, EpiData V 4.6 and to analyze SPSS V 26 were used. To examine the association between work-related burnout and its predictor variables, both bivariable (p &lt; 0.2) and multivariable (&lt;0.05) logistic regression analyses were performed, and statistical significance was established via multivariable logistic regression.ResultsThe response rate in this study was 96.05% (n = 608). The majority, 452 (74.3%) of the police officers, were male; the median (IQR) age of participants was 28. In the past six months, 45.7% of the police officers had experienced work-related burnout (n = 278). Being female, having a high job demand, having a high level of organizational police stress, having a moderate level of operational police stress, having a high level of operational police stress, experiencing job dissatisfaction, and sleeping troubles were risk factors significantly related to the occurrence of work-related burnout among police officers.ConclusionAccording to this study, a significant number of police officers suffer from burnout due to their work. Police officers’ work-related burnout was found to be influenced by factors such as sex, job demands, job satisfaction, workplace stress, organizational police stress, and sleeping troubles. To address this problem, improving the handling of work pressure, developing a stress management program, finding joy at work by improving interpersonal relationships and working conditions, offering support and inspiration to female police officers, and ensuring sufficient and restful sleep are advised.
Brillouin frequency shift measurement by zero-crossing point search in virtually synthesized spectra of Brillouin gain and loss
Authors: Nonogaki Hayato , Sei Daichi , Zan Mohd Saiful Dzulkefly , Tanaka Yosuke 
Published: April 2024

Abstract
We demonstrate a method for fast and precise Brillouin frequency shift measurement based on searching for the zero-crossing point of a virtually composed spectrum of Brillouin gain and loss obtained by a dual-frequency probe beam. Simulations and experiments show that searching for the zero-crossing point of a virtually synthesized Brillouin gain spectrum can be easily done without a large error compared with peak search of the Brillouin gain spectrum in the conventional method.
Factors Affecting Pregnancy Complications in Ghana
Authors: Wiafe Yaw K. , Asamoah Andrews , Akweongo Patricia , Kumah Augustine 
Published: April 2024

ABSTRACT

Introduction
The prevalence of maternal mortality continues to be a significant health concern across the world. In Ghana, pregnancy-related complications in the previous 5 years account for 12% of all deaths among women 15 to 49 years. More than half of these deaths were avoidable if early assessment had been done. However, assessment of the pooled prevalence of pregnancy-related complications among pregnant women to inform policy is limited. This study sought to determine the factors contributing to pregnancy complications in Ghana.

Methods
Using a systematic sampling technique, a facility-based cross-sectional study was conducted among 415 pregnant women who attended antenatal care (ANC) services at Mamprobi Hospital. Bivariate and multiple logistics regression analyses were conducted to test significant factors determining pregnancy complications. The results of regression analysis are reported in odds ratio. Statistical significance was set at p &lt; 0.05.

Results
The mean age of the participants was 31.6 ± 6.6 years. The incidence of pregnancy complications among the pregnant women was 51.8% (95% CI, 0.47–0.56) The incidence of pregnancy complications among the women was significantly determined by age (adjusted odds ratio [AOR], 6.1; CI, 1.19–30.76), record of pregnancy complication (AOR, 2.5; CI, 1.35–4.49), ANC visit (AOR, 6.1; CI, 2.14–17.70), and family history of pregnancy complication (AOR, 3.6; CI, 1.25–10.40). Other significant factors included a record of abortion (AOR, 7.8; CI, 4.21–14.32), knowledge about obstetric danger signs (AOR, 2.4; CI, 1.21–4.88), and experiencing at least one obstetric danger sign during pregnancy (AOR, 6.6; CI, 3.30–13.29).

Conclusion
The incidence of pregnancy complications was comparatively high among the women who used ANC services at Mamprobi Hospital. Early initiation of ANC services for pregnant women is an essential tool for addressing some of the challenges of early onset of some pregnancy complications, including anemia in pregnancy and preeclampsia. Midwives and other health workers who engage pregnant women should encourage their clients to initiate ANC visits at an early stage.