bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the statistical physics modeling of dye adsorption onto anionized nylon: Consequent new interpretations
Authors: Khalfaoui M. , Nakhli A. , Knani S. , Baouab H. V. , Ben Lamine A. 
Published: December 2011

AbstractExperimental adsorption isotherm of two basic dyes: Basic Blue 3 and Basic Red 24 from aqueous solution onto modified nylon 6,6 were analyzed by using a double layer adsorption model with two energy levels. Such model is based on statistical physics treatment. The parameters involved in the analytical expression of this model such as the fraction or the number of adsorbed dye molecule(s) per site, n, the receptor sites density, NM, and the energetic parameters, c1 and c2, were determined by fitting the experimental adsorption isotherms at four temperatures between 293 and 353 K with different degrees of grafting between 20 and 80%. The evolution of these parameters versus temperature and the grafting percent allows us to interpret and better understand this adsorption process at molecular level. Two different behaviors of the two dye molecules were highlighted according to their localized and non localized charges. The configurational entropy at various temperatures has also been studied. This parameter allowed to deduce some results related to the evolution of the disorder at the adsorption surface. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
The crystallization behavior and mechanical properties of polylactic acid in the presence of a crystal nucleating agent
Authors: Tang Zhaobin , Zhang Chuanzhi , Liu Xiaoqing , Zhu Jin 
Published: December 2011

AbstractThe crystallization behavior of polylactic acid (PLA) was studied in the presence of a crystal nucleating agent, ethylenebishydroxystearamide (EBH). The crystallization rate and crystallinity were significantly increased with addition of EBH. The isothermal crystallization half‐time at 105°C was decreased from 18.8 minutes for neat PLA to 2.8 minutes for PLA with 1.0 wt % of EBH. The crystallinity of PLA with 1.0 wt % EBH was about 35% after 5‐minute annealing at 105°C. Like neat PLA, the double melting peaks were also observed for nucleated PLA. The changes of the double melt peaks were investigated with various crystallization temperatures, heating rates, and annealing times. The heat deflection temperature (HDT) of nucleated PLA was up to 93°C after annealing. The correlation between crystallinity and HDT was demonstrated. A percolation threshold of crystallinity was found corresponding to HDT. The crystal size of nucleated PLA was significantly decreased with addition of EBH. The mechanical properties of annealed PLA blends simultaneously; showed improved modulus and impact strength. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Aminolytic depolymerization of poly (ethylene terephthalate) bottle waste by conventional and microwave irradiation heating
Authors: Parab Yogesh S. , Pingale Navnath D. , Shukla Sanjeev R. 
Published: December 2011

AbstractPoly (ethylene terephthalate) (PET) is the most popular thermoplastic polymer. The ever‐growing production and utilization of PET has led to postconsumer waste disposal problems because of its nonbiodegradability. The chemical depolymerization of PET waste is a possible remedy, as it results in some recyclable products. The aminolytic depolymerization of PET bottle waste with hydrazine monohydrate by conventional and nonconventional (with microwave irradiation) heating was carried out with simple chemicals as catalysts, such as sodium acetate and sodium sulfate. The yield of the product was optimized through variations in the time of aminolysis, the catalyst concentration, and the PET:hydrazine monohydrate ratio. The pure product obtained in good yield (86%) was analyzed by Fourier transform infrared spectroscopy, NMR, and differential scanning calorimetry and was identified as terephthalic dihydrazide. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
CO metabolism, sensing, and signaling
Authors: Gullotta Francesca , di Masi Alessandra , Coletta Massimo , Ascenzi Paolo 
Published: December 2011

AbstractCO is a colorless and odorless gas produced by the incomplete combustion of hydrocarbons, both of natural and anthropogenic origin. Several microorganisms, including aerobic and anaerobic bacteria and anaerobic archaea, use exogenous CO as a source of carbon and energy for growth. On the other hand, eukaryotic organisms use endogenous CO, produced during heme degradation, as a neurotransmitter and as a signal molecule. CO sensors act as signal transducers by coupling a “regulatory” heme‐binding domain to a “functional” signal transmitter. Although high CO concentrations inhibit generally heme‐protein actions, low CO levels can influence several signaling pathways, including those regulated by soluble guanylate cyclase and/or mitogen‐activated protein kinases. This review summarizes recent insights into CO metabolism, sensing, and signaling.
Transvenous Extraction of Pacemaker Leads in Infective Endocarditis With Vegetations ≥20 mm: Our Experience
Authors: Pérez Baztarrica Gabriel , Gariglio Luis , Salvaggio Flavio , Reolón Estela , Blanco Norberto , Mazzetti Hector , Villecco Sebastián , Botbol Alejandro , Porcile Rafael 
Published: December 2011

AbstractBackground:According to published evidence, treatment of infective endocarditis (IE) associated with cardiovascular implantable electronic devices (CIEDs) should include complete removal of the system. Several publications have shown that transvenous removal is an effective and safe nonthoracotomy approach in patients with large vegetations, but experiences with vegetations larger than 20 mm have rarely been reported.Hypothesis:Our aim was to describe our experience in percutaneous removal of CIEDs in patients with IE with large vegetations.Methods:The data were collected retrospectively and analyzed prospectively. We evaluated in‐hospital morbidity and mortality related to percutaneous removal of vegetations ≥20 mm. This included 8 cases with a follow‐up period of 20 months. We removed 100% of leads in the study population.Results:Two patients experienced minor complications. No patient experienced subclavian vein laceration, hemothorax and lead fracture, or severe tricuspid regurgitation. After the removal procedure, 2 patients had symptoms compatible with pulmonary embolism. Both in‐hospital mortality and mortality at follow‐up were zero.Conclusions:Transvenous extraction of pacing leads with larger vegetations is a feasible technique. There was a tendency toward symptomatic pulmonary embolism in patients with vegetations larger than 20 mm; however, morbidity and mortality were not influenced. We agree with the consensus that this procedure is highly useful and that the selection of the removal techniques will depend not only on the size of vegetation but also on prior cardiopulmonary conditions, concomitant cardiac surgery, atrial septal defect with risk of paradoxical embolism, center experience, and the possibility of complete removal of the device. © 2011 Wiley Periodicals, Inc.The authors have no funding, financial relationships, or conflicts of interest to disclose.
Influence of earthworm activity on microbial communities related with the degradation of persistent pollutants
Authors: Natal-da-Luz Tiago , Lee Iwa , Verweij Rudo A. , Morais Paula V. , Van Velzen Martin J.M. , Sousa José Paulo , Van Gestel Cornelis A.M. 
Published: December 2011

Abstract
Earthworms may promote the biodegradation of polycyclic aromatic hydrocarbons (PAHs) in soil, but the mechanism through which they exert such influence is still unknown. To determine if the stimulation of PAH degradation by earthworms is related to changes in microbial communities, a microcosm experiment was conducted consisting of columns with natural uncontaminated soil covered with PAH-contaminated dredge sediment. Columns without and with low and high Eisenia andrei densities were prepared. Organic matter and PAH content, microbial biomass, and dehydrogenase activity (DHA) were measured in soil and sediment over time. Biolog Ecoplate™ and polymerase chain reaction using denaturing gradient gel electrophoresis were used to evaluate changes in metabolic and structural diversity of the microbial community, respectively. Earthworm activity promoted PAH degradation in soil, which was significant for biphenyl, benzo[a]pyrene, and benzo[e]pyrene. Microbial biomass and DHA activity generally did not change over the experiment. Earthworm activity did change microbial community structure, but this did not affect its functioning in terms of carbon substrate consumption. Results suggest no relationship between changes in the microbial community by earthworm activity and increased PAH disappearance. The role of shifts in soil microbial community structure induced by earthworms in PAH removal needs further investigation. Environ. Toxicol. Chem. 2012;31:794–803. © 2011 SETAC
Comparative toxicity of four chemically dispersed and undispersed crude oils to rainbow trout embryos
Authors: Wu Dongmei , Wang Zhendi , Hollebone Bruce , McIntosh Stephen , King Tom , Hodson Peter V. 
Published: December 2011

Abstract
The chronic toxicity of crude oil to fish embryos depends on the chemical constituents of the test oil and on factors that control the exposure of embryos to those constituents. The partitioning of chemicals from oil to water depends on the surface area of oil exposed to water and thus on the susceptibility of oil to be dispersed into droplets. The chronic toxicity of four different crude oils to embryos of rainbow trout (Oncorhynchus mykiss) was measured by exposure to the water-accommodated fraction (WAF; no droplet formation) and to the chemically enhanced WAF (CEWAF) of each oil. When effects were compared with the amount of WAF or CEWAF added to test solutions, chemical dispersion increased toxicity dramatically, by &gt;35 to &gt;300-fold, with the smallest difference measured for the lightest and least viscous oil. When effects were compared with measured concentrations of oil in test solutions, there were no differences in toxicity between WAF and CEWAF treatments, indicating that chemical dispersion promoted droplet formation and the partitioning of hydrocarbons from oil to water. On a dilution basis, the differences in toxicity among the four oils were correlated with the concentrations in oil of polynuclear aromatic hydrocarbons (PAH), particularly those with three to five rings, and with their viscosity, an index of dispersibility. However, when PAH concentrations were measured in solution, toxicity did not vary substantially among the four oils, suggesting that the PAH of each oil had equivalent toxicities and that differences in toxicity represented differences in dispersability. Environ. Toxicol. Chem. 2012;31:754–765. © 2011 SETAC
Association of serum bilirubin and promoter variations in HMOX1 and UGT1A1 genes with sporadic colorectal cancer
Authors: Jirásková Alena , Novotný Jan , Novotný Ladislav , Vodic̆ka Pavel , Pardini Barbara , Naccarati Alessio , Schwertner Harvey A. , Hubác̆ek Jaroslav A. , Punc̆ochár̆ová Lucie , Šmerhovský Zdenek , Vítek Libor 
Published: December 2011

AbstractHeme oxygenase‐1 (HMOX1) and bilirubin UDP‐glucuronosyltransferase (UGT1A1) enzymes, both involved in bilirubin homeostasis, play an important role in the oxidative stress defense. The objective of our study was to assess the effect of promoter variations of HMOX1 and UGT1A1 genes and of serum bilirubin on the risk of sporadic colorectal cancer (CRC). This exploratory case‐control study was based on 777 CRC patients and 986 controls from the Czech Republic. The (GT)n and (TA)n dinucleotide variations in HMOX1 and UGT1A1 gene promoters, respectively, were determined by fragment analysis. In addition, the A(‐413)T variant in HMOX1 promoter was also analyzed using a polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) method. Serum bilirubin levels were compared in a subset of 174 cases and 247 controls, for whom biochemical data were available. After adjustment for age, a significant association between CRC risk and UGT1A1*28 allele carrier status was detected [odds ratio (95% confidence intervals) = 0.80 (0.60–0.97), p = 0.022]. No association between CRC risk and individual HMOX1 gene variants was observed, although a diplotype analysis revealed an increased risk for a specific HMOX1 genotype combination. These effects were more pronounced in males. Substantially lower serum bilirubin levels were detected in CRC patients compared to the controls (p < 0.001); each 1 μmol/L decrease in serum bilirubin was associated with a 7% increase of CRC risk (p < 0.001). In conclusion, UGT1A1*28 allele carrier status might be a protective factor against the development of CRC in the male population, whereas low serum bilirubin levels are associated with an increased risk of CRC in both genders.
Red meat consumption and cancer: Reasons to suspect involvement of bovine infectious factors in colorectal cancer
Authors: zur Hausen Harald 
Published: December 2011

AbstractAn increased risk for colorectal cancer has been consistently reported for long‐time consumption of cooked and processed red meat. This has frequently been attributed to chemical carcinogens arising during the cooking process of meat. Long‐time fish or poultry consumption apparently does not increase the risk, although similar or higher concentrations of chemical carcinogens were recorded in their preparation for consumption. The geographic epidemiology of colorectal cancer seems to correspond to regions with a high rate of beef consumption. Countries with a virtual absence of beef in the diet (India) or where preferably lamb or goat meat is consumed (several Arabic countries) reveal low rates of colorectal cancer. In China, pork consumption has a long tradition, with an intermediate colorectal cancer rate. In Japan and Korea, large scale beef and pork imports started after World War II or after the Korean War. A steep rise in colorectal cancer incidence was noted after 1970 in Japan and 1990 in Korea. The consumption of undercooked beef (e.g., shabu‐shabu, Korean yukhoe and Japanese yukke) became very popular in both countries. The available data are compatible with the interpretation that a specific beef factor, suspected to be one or more thermoresistant potentially oncogenic bovine viruses (e.g., polyoma‐, papilloma‐ or possibly single‐stranded DNA viruses) may contaminate beef preparations and lead to latent infections in the colorectal tract. Preceding, concomitant or subsequent exposure to chemical carcinogens arising during cooking procedures should result in increased risk for colorectal cancer synergistic with these infections.
Weight change and prostate cancer incidence and mortality
Authors: Bassett Julie K. , Severi Gianluca , Baglietto Laura , MacInnis Robert J. , Hoang Hoa N. , Hopper John L. , English Dallas R. , Giles Graham G. 
Published: December 2011

AbstractThe relationship between obesity and prostate cancer risk has been studied extensively but with inconsistent findings, particularly for tumor aggressiveness. Few studies have investigated weight change and prostate cancer incidence or mortality. Using the Melbourne Collaborative Cohort Study, which recruited 17,045 men aged between 40 and 69 years at study entry, we investigated associations between reported weight and body mass index (BMI) at age 18 and measured at study entry, height, weight change between age 18 and study entry and prostate cancer incidence and mortality. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression. During follow‐up (mean = 15 years) of 16,514 men, we ascertained 1,374 incident prostate cancers of which 410 were classified as aggressive, and 139 deaths from prostate cancer. The incidence of all prostate cancer was not associated with body size or weight change. Weight and BMI at study entry were positively associated with aggressive prostate cancer risk (HR = 1.06, 95% CI: 1.00–1.13 per 5 kg; HR = 1.27, 95% CI: 1.08–1.49 per 5 kg/m2) and prostate cancer mortality (HR = 1.12, 95% CI: 1.01–1.23 per 5 kg; HR = 1.49, 95% CI: 1.11–2.00 per 5 kg/m2). Weight gain was positively associated with prostate cancer mortality (HR = 1.13, 95% CI: 1.02–1.26 per 5 kg increment); the HR for ≥20 kg weight gain between age 18 and study entry compared to <5 kg gain over this period was 1.84, 95% CI: 1.09–3.09. Higher adult weight and BMI increases the risk of aggressive prostate cancer and mortality from prostate cancer. Weight gain during adult life is associated with increased prostate cancer mortality.
Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B‐cell and Burkitt lymphomas
Authors: Scholtysik René , Nagel Inga , Kreuz Markus , Vater Inga , Giefing Maciej , Schwaenen Carsten , Wessendorf Swen , Trümper Lorenz , Loeffler Markus , Siebert Reiner , Küppers Ralf 
Published: December 2011

AbstractA single nucleotide polymorphism‐chip analysis of 98 cases of aggressive B‐cell lymphomas revealed a recurrent deletion at 19p13 in nine of the cases. Six further cases with deletions encompassing this region were found in array‐comparative genomic hybridization data of 295 aggressive B‐cell lymphomas from a previous study. Three cases even showed a homozygous deletion, suggesting a tumor suppressor gene in the deleted region. Two genes encoding members of the tumor necrosis factor superfamily (TNFSF) were located in the minimally deleted region, that is, TNFSF7 and TNFSF9. As no mutations were found within the coding exons of the remaining alleles in the lymphomas with heterozygous deletions, we speculate that the deletions may mostly function through a haploinsufficiency mechanism. The cases with deletions encompassed both diffuse large B‐cell lymphomas and Burkitt lymphomas, and a deletion was also found in a Hodgkin lymphoma cell line. Thus, TNFSF7 and TNFSF9 deletions are recurrent genetic lesions in multiple types of human lymphomas.
Low risk of type‐specific carcinogenic HPV re‐appearance with subsequent cervical intraepithelial neoplasia grade 2/3
Authors: Rodríguez Ana Cecilia , Schiffman Mark , Herrero Rolando , Hildesheim Allan , Bratti Concepción , Sherman Mark E. , Solomon Diane , Guillén Diego , Alfaro Mario , Morales Jorge , Hutchinson Martha , Cheung Li , Wacholder Sholom , Burk Robert D. 
Published: December 2011

AbstractCarcinogenic human papillomavirus (HPV) infections are very common after sexual debut and nearly all become undetectable (“clear”) within a few years. Following clearance, the long‐term risks of type‐specific HPV re‐appearance and subsequent risk of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) are not well defined. In the 7‐year, population‐based cohort study in Guanacaste, Costa Rica, we studied how often type‐specific carcinogenic HPV infections re‐appeared after clearance and how often re‐appearance led to CIN2+. We considered 1,740 carcinogenic HPV infections detected by MY09/11 PCR among 2,805 women (18–91 years old, median 34) who were actively followed at 6‐ or 12‐month intervals. We identified women with one or more type‐specific HPV infections that cleared and re‐appeared and further defined a subgroup of “definite clearance and re‐appearance” (≥2 intervening negative results over a period of ≥1 year). We determined the absolute risk of CIN2+ among the different groups. p values are two‐sided. Only 7.7% (81/1,052) of HPV‐infected women had intervening negative results. Very few (3.7%, 39/1,052) had “definite clearance and re‐appearance”, of which 5.1% (2/39) subsequently persisted to a diagnosis of CIN2. There were zero CIN3+ lesions. Extremely few women (2/2,805 of women in our cohort) had a type‐specific carcinogenic HPV infection clear, re‐appear and lead to CIN2+. If confirmed, this argues against vaccination to avoid re‐appearance that leads to precursor lesions and against the need of frequent HPV screening after initial negative results.
Synthesis, characterization, and in vitro biological studies of some novel pyran fused pyrimidone derivatives
Authors: Mistry Prashant T. , Kamdar Nimesh R. , Haveliwala Dhaval D. , Patel Saurabh K. 
Published: January 2012

AbstractA variety of pyrano[2,3‐d]pyrimidine‐5‐one derivatives 5, 5a, 5b, 5c, 5d, 5e, 5f, 5g, 5h, 5i, 5j, 6, 6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h, 6i, 6j have been synthesized from 6‐amino‐4‐(substituted phenyl)‐5‐cyano‐3‐methyl‐1‐phenyl‐1,4‐dihydropyrano[2,3‐c]pyrazole derivatives 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h, 4i, 4j via cyclization using formic acid and acetic acid. All the newly synthesized compounds have been characterized by IR, 1H NMR, 13C NMR, and elemental analysis. All the synthesized compounds have been screened for antibacterial, antifungal and antitubercular activity. J. Heterocyclic Chem., (2012).
Reaction of 2‐Alkoxy‐4,5‐diphenyl‐1,3‐oxazin‐6‐one with different alcohols and elucidation of the products
Authors: Assadieskandar Amir , Amini Mohsen , Haukka Matti , Shafiee Abbas 
Published: January 2012

AbstractReaction of 2‐methoxy‐4,5‐diphenyl‐1,3‐oxazin‐6‐one 1a with methanol was studied, and the product of the reaction was determined by spectroscopic data and X‐ray analysis. In addition, a series of (Z)‐alkyl 3‐(alkoxycarbonylamino)‐2,3‐diphenylacrylate 4 was synthesized and characterized. J. Heterocyclic Chem., (2012).
Synthesis of new thieno[2,3‐d]pyrimidines, thieno[3,2‐e]pyridines, and thieno[2,3‐d][1,3]oxazines
Authors: Kanawade Shrikant B. , Patil Shivaraj P. , Nikam Prashant S. , Gangurde Sachin A. , Jachak Madhukar N. , Toche Raghunath B. 
Published: January 2012

Abstracto‐Aminothiophene dicarbonitrile 1 on neat reaction with cyclic ketones in anhydrous ZnCl2 yielded mixture of fused aminopyridine 3 and iminospirooxazine 4 derivatives. Similarly, pyrimidine derivatives 5 and 8 were obtained by the reaction of this intermediate 1 with formic acid and DMF‐DMA followed by hydrazine hydrate, respectively. The reaction of o‐amino‐thiophene dicarboxamide 2 at ambient temperature with cyclic ketones yielded spiropyrimidine 10 as a sole product in quantitative yield. The regioselective anellated pyrimidine 9, 11, and dihydropyrimidine 12 derivatives were also obtained by the reaction with aromatic aldehydes in presence of piperidine and iodine respectively. J. Heterocyclic Chem., (2012).
Improved synthesis of 2‐methoxyphenothiazine
Authors: Ruan Jian‐Cheng , Zhang Tao , Wang Shuai , Liu Jin‐Qiang , Qian Chao , Chen Xin‐Zhi 
Published: January 2012

AbstractA procedure for synthesis of 2‐methoxyphenothiazine (1) has been developed, starting from resorcinol and aniline by condensation, following methylation and cyclization. p‐Toluenesulfonic acid and polysubstituted aromatics were employed as the catalyst of condensation and the solvent of cyclization, respectively, to improve the yield. The use of parallel experiments, statistical experimental design, and multivariate modeling made the total yield of the procedure as high as 74.2%. J. Heterocyclic Chem., (2012).
Convenient syntheses of bulky group containing imidazolium ionic liquids
Authors: Kumar Neeraj , Jain Rahul 
Published: January 2012

AbstractWe report syntheses of bulky group containing imidazolium based ionic liquids. The bulky groups were introduced at N‐1, C‐2, and N‐3 positions of the imidazole ring using convenient methodologies. J. Heterocyclic Chem., (2012).
Tandem synthesis of 2,3‐dihydroquinazolin‐4(1H)‐ones on grinding under solvent‐free conditions
Authors: Ding Quan‐Sheng , Zhang Ji‐Lei , Chen Jiu‐Xi , Liu Miao‐Chang , Ding Jin‐Chang , Wu Hua‐Yue 
Published: January 2012

AbstractCitric acid promoted synthesis of a mini‐library 2,3‐dihydroquinazolin‐4(1H)‐ones with good to excellent yields is achieved by tandem reaction of anthranilamides (or anthranilhydrazides) with aldehydes on grinding at room temperature under solvent‐free conditions. This method has notable advantages in terms of simple workup, short reaction time, cost‐effective, and environmentally benign. J. Heterocyclic Chem., (2012).