bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sentido de Vida y su Influencia en la Salud Mental
Authors: Saleme Negrete Yadith , Coronado Martinez Ever José 
Published: May 2024

Esta investigación trata sobre el sentido de vida y su influencia en la salud mental; por tanto, se plantearon dos interrogantes ¿Qué determina el sentido de vida de un individuo? Y ¿Cómo el sentido de vida puede contribuir al fortalecimiento de la salud mental y la prevención de enfermedades mentales? Para tal fin, se realizó una revisión documental de los resultados obtenidos por autores que indagaron sobre el sentido vida (SV) y su implicación en la salud mental (SM), categorías de análisis y se determinó cuatro fases adaptadas de Guirao-Goris, et al. (2008), para su estudio que son: 1. Planteamiento de preguntas directoras, 2. Definir criterios de selección, 3. Sistematización de la información y, por último, establecer el análisis. Se concluye que, en la formación del sentido de vida se hace necesario tres aspectos fundamentales: la familia, la educación y la sociedad. Entonces se hace indispensable, desde la familia, la educación y la sociedad trabajar de manera conjunta para desarrollar un sentido de vida, el cual se convierte en un factor protector del individuo y potencia una mejor calidad de vida, reflejada en la buena salud tanto física como mental y un mayor disfrute de su existencia.
Pelatihan Basic Life Support Pada Masyarakat Pesisir Molotabu sebagai Upaya Penanggulangan Henti Napas & Jantung pada Wisatawan
Authors: Dungga Elvie Febriani , Liputo Gusti Pandi 
Published: May 2024

Obyek wisata laut dan pantai terdapat resiko kegawatdaruratan yang dapat terjadi, yaitu tenggelam saat berenang di pantai. Tenggelam (drowning) adalah cedera karen perendaman (submersion/immersion) yang dapat mengakibatkan kematian dalam waktu kurang dari 24 jam. Wisata pantai masih menjadi salah satu destinasi paling banyak diminati masyarakat di Gorontalo pada akhir pekan. Hasil observasi didapatkan aktivitas yang sering dilakukan oleh masyarakat saat berkunjung ke pantai adalah berenang yang memiliki risiko terjadinya tenggelam. Pada korban tenggelam berisiko mengalami henti napas dan jantung, sehingga butuh pertolongan pertama yakni Bantuan Hidup Dasar atau Basic Life Support (BLS). Pertolongan dalam keadaan gawat darurat ini bisa dilakukan oleh siapa saja yang penting tahu cara melakukannya. Hasil wawancara dengan masyarakat yang tinggal di pesisir pantai dan juga termasuk yang menyediakan fasilitas di pantai Botutonuo menyatakan tidak tahu penanganan awal yang benar terkait Basic Life Support, untuk itu peran dari tenaga kesehatan termasuk mahasiswa kesehatan yang sudah memiliki ilmu dan pengetahuan terkait BLS dibutuhkan dan dapat dilakukan pelatihan kepada masyarakat atau pengelola pantai Botutonuo. Kegiatan ini dilaksanakan selama 45 hari yakni mulai dari 17 Juli – 30 Agustus 2023 dengan jumlah peserta sebanyak 17 mahasiswa.
Reliability Of Transvaginal Ultrasound Measured Endometrial Thickness In Diagnosis Of Endometrial Cancer In Postmenopausal Women
Authors: Bibi Ayesha , Majeed Noreen , Mushtaq Irum , Kalsoom Shabana , Azhar Ruqya , Mehdi Mehreen 
Published: May 2024

Abstract
Objective: Dilatation and curettage have been replaced by ultrasound measurement of uterine endometrial thickness (ET) especially by Transvaginal ultrasound (TVS) as a first step in the workup of women with postmenopausal bleeding for many years. Still, there is no unanimity for endometrial thickness cut-off value to define abnormality. We used an endometrial thickness of 4mm as a cut-off value in this study.
Methods: This cross-sectional validation study included 120 patients who presented with postmenopausal bleeding in OPD of POF hospital from 01-12-2017 to 1-06-2018.TVS measured endometrial thickness ≥4mm was assumed positive for malignancy and ˂ 4 mm was taken negative for malignancy. The TVS findings of patients were compared with the histopathology report of endometrial sampling, which was performed in OPD by manual vacuum aspirator (MVA). Histopathology report was taken as a reference standard to confirm or refute the diagnosis of transvaginal ultrasound.
Results: On TVS, 54 patients had ≥ 4mm endometrial thickness (taken positive for malignancy) while 66 patients had <4 mm endometrial thickness (taken negative for malignancy). Histopathology of the endometrium (reference standard) revealed that 47 (39.17%) patients had malignancy and 73(60.83%) patients did not have malignancy. The reliability of transvaginal ultrasound (TVS) using 4mm cut-off point ET in detecting endometrial malignancy in patients presenting with uterine bleeding after menopause, keeping histopathological findings as a reference standard showed 89.36% sensitivity, 83.56%, specificity, 92.42% negative predictive value and 77.78% positive predictive value & 85.83% accuracy rate.
Conclusion: We concluded that there was a low probability of endometrial malignancy in women with ˂ 4 mm transvaginal ultrasound (TVS)measured endometrial thickness (ET).TVS may replace invasive endometrial sampling in cases of postmenopausal bleeding with ˂ 4mm ET.
Mortality Trends In Pre COVID And Pandemic Era In A Tertiary Care Setting
Authors: Khan Hareema Saeed , Dar Savida Ilyas , Faisal Tayyaba , Shah Faridullah , Aslam Rabbia , Asim Maheen 
Published: May 2024

Objective: The coronavirus pandemic has emphasized stay-at-home and social distancing policies. Since the beginning of the outbreak of COVID-19, there has been a declining trend of hospital mortality indicating that the pandemic might keep patients from seeking emergency care in a hospital setting. This study was carried out to determine the mortality trends pre-COVID and pandemic periods in a tertiary care hospital.
Methods:
Study design: Retrospective observational study
Place and Duration: 1st January 2019 to December 2021 at Federal Government Polyclinic (FGPC) Hospital Islamabad
It was a retrospective review done on death data of pre-COVID (January-December 2019) and pandemic(January 2020-December 2021) period. Data on death was retrieved from medical male and female wards, medical ICU and isolation ward. The mortality rate was measured for both pre-COVID and pandemic periods along with co-morbid for the pandemic period. Descriptive statistics were measured with the SPSS software version. 23. Association with age, gender and mortality was observed using a chi-square test taking p value ≤ 0.05 as significant.
Result: In this study of the 366 deaths, the average age of patients in the pre-COVID and pandemic era was57.40±17.910 and 64.31±16.065 respectively. The males and females were 50.9% and 49.1% in the pre-COVID period while 61.5% and 38.5% in the pandemic period. The frequency of deaths was 46.7% in the pre COVID and 53.3% in the pandemic period with a p-value <0.05. Patients with co-morbid died more in the pandemic era.
Conclusion: It was observed that hospital mortality trends were in decline during the COVID-19 pandemic in our setting which may be associated with lockdown, decreased access to the hospitals or fear of going to hospital.
Treatment Approaches to Speech Sound Disorders: A Scoping Review
Authors: Noreen Hafsa , Mumtaz Nazia , Saqulain Ghulam 
Published: May 2024

Objective: The objective was to highlight and review different therapeutic approaches to cater to speech sound disorders in Pakistan.
Methodology: To find the different therapeutic approaches, a literature search for related articles/ publications was conducted using the Keywords “speech sound disorders, phonological disorders, articulation disorder and a combination of words using search engines like Google & and databases like PubMed and other websites. Around 130 publications, reports, and articles were downloaded, of which 25 were used for literature review.
Results: There are many treatments used to cater for speech sound disorders including contextual utilisation, phonological contrast, complexity, core vocabulary, cycles phonological pattern, distinctive feature therapy, metaphor therapy, naturalist speech intelligibility, non-speech oral-motor therapy, speech sound perception training and bilingual or cross-lingual approach. However, novel trends like the use of hybrid treatment, speech motor learning- phonetic placement approach, blocked practice versus serial practice schedule & interventions using biofeedback need to be utilized.
Conclusion: Treatment approaches in use include contextual utilisation, phonological contrast, complexity, core vocabulary, cycles phonological pattern, distinctive feature therapy, metaphor therapy, naturalist speech intelligibility, non-speech oral-motor therapy, speech sound perception training and bilingual or cross-lingual approach, however, novel treatments need to be utilised.
Keywords: Articulation disorders, Phonological disorders, Phonological Representations
Relativistic Jet Ejections from Slim Disks
Authors: Inoue Hajime 
Published: May 2024

Abstract
A mechanism for the ejection of relativistic jets from slim disks is studied. Since radiation pressure is dominant in the slim disk, radiative energy flows along the pressure gradient in the vertical direction. The divergence of the radiative flux tells us that the flow of radiative energy from a bottom layer near the equatorial plane is absorbed by another layer above the boundary surface. The absorbed energy accumulates in the upper layer as the matter advances inward, and calculations show that the specific energy of the flow in the upper layer can be as large as ∼c
2 near the black hole when the accretion rate through the upper layer is relatively low. Since the specific energy ∼c
2 is much larger than the gravitational energy, the height of the upper layer could significantly increase then. Hence, the innermost part of the upper layer after almost all the angular momentum has been removed could have a much greater height than the size of the black hole, and the flow could collide with itself around the central axis of the disk, bouncing back from the axis while simultaneously expanding along it. The flow is expected to go outward along the central axis and to become supersonic due to the change in its cross section, finally producing relativistic jets.
Forming Mercury from Excited Initial Conditions
Authors: Scora Jennifer , Valencia Diana , Morbidelli Alessandro , Jacobson Seth 
Published: May 2024

Abstract
Mercury is notoriously difficult to form in Solar System simulations, due to its small mass and iron-rich composition. Smooth particle hydrodynamics simulations of collisions have found that a Mercury-like body could be formed by one or multiple giant impacts, but due to the chaotic nature of collisions, it is difficult to create a scenario where such impacts will take place. Recent work has found more success forming Mercury analogues by adding additional embryos near Mercury’s orbit. In this work, we aim to form Mercury by simulating the formation of the Solar System in the presence of the giant planets Jupiter and Saturn. We test out the effect of an inner disk of embryos added on to the commonly used narrow annulus of initial material. We form Mercury analogues with core-mass fractions (CMFs) > 0.4 in ∼10% of our simulations, and twice that number of Mercury analogues form during the formation process but are unstable and do not last to the end of the simulations. Mercury analogues form at similar rates for both disks with and without an inner component, and most of our Mercury analogues have lower CMFs than that of Mercury, ∼0.7, due to significant accretion of debris material. We suggest that a more in-depth understanding of the fraction of debris mass that is lost to collisional grinding is necessary to understand Mercury’s formation, or some additional mechanism is required to stop this debris from accreting.
The Dependence of Gamma-Ray Burst Jet Collimation on Black Hole Spin
Authors: U. Hurtado Valeria , Lloyd-Ronning Nicole M. , Miller Jonah M. 
Published: May 2024

Abstract
Gamma-ray bursts (GRBs) are the most luminous events in the Universe and are excellent laboratories to study extreme physical phenomena in the cosmos. Despite a long trajectory of progress in understanding these highly energetic events, there are still many observed features that are yet to be fully explained. Observations of the jet opening angle of long gamma-ray bursts (LGRBs) suggest that LGRB jets are narrower for those GRBs at higher redshift. This phenomenon has been explained in the context of collimation by the stellar envelope, with denser (lower metallicity) stars at higher redshifts able to collimate the jet more effectively. However, until now, the dependence of the jet opening angle on the properties of the central engine has not been explored. We investigate the effect of black hole spin on the jet collimation angle for a magnetically launched jet, using the general relativistic radiation magnetohydrodynamical code ν
bhlight. We present 3D results for a range of spin values. The simulations show that higher-spinning black holes tend to create narrower jets. If indeed LGRB progenitors in the early Universe are able to produce black hole central engines with higher spin, this could account for at least some of the observed jet opening angle-redshift correlation.
Discovery of an [O iii] Emission Shell around the X-Ray Binary CI Cam
Authors: Fesen Robert A. , Drechsler Marcel , Martino Nicolas , Sainty Yann 
Published: May 2024

Abstract
We report the serendipitous discovery of a

8
′
×
12
′

emission shell brightest in [O iii] centered on the X-ray binary B[e] star, CI Cameleopardalis (CI Cam). This shell, detected during a survey of optical emission associated with the Galactic supernova remnant G150.3+4.5, is seen outside but immediately adjacent to the remnant’s optical filaments along its northwestern edge. Assuming this shell is related to CI Cam’s strong winds and transient outbursts, the adoption of CI Cam’s Gaia DR3 statistically corrected distance of 4.1

−
0.2

+
0.3

kpc yields shell dimensions ≃9.5 pc × 14.3 pc. While the distance to the G150.3+4.5 remnant is uncertain, the appearance of CI Cam’s emission shell so close to the SNR’s optical filaments appears likely to be a chance coincidence.
Les formes d’organisation du travail dans les administrations publiques
Authors: Nocenti Brice 
Published: May 2024

Comment mesurer la diffusion des modèles organisationnels issus du « nouveau management » dans l’État, les hôpitaux et les collectivités locales ? Cet article mobilise les enquêtes Conditions de travail 2005 à 2019 pour étendre aux administrations publiques les travaux statistiques portant sur les formes d’organisation du travail, habituellement réservés aux entreprises. L’analyse empirique en distingue cinq : l’autonomie du métier, l’autonomie évaluée, le contrôle direct, le lean management et le taylorisme flexible. Les professions organisées du public connaissent une érosion de leur autonomie collective sous l’effet de la diffusion des instruments d’évaluation formalisée tout en demeurant dans des organisations très qualifiantes. Les cadres de l’État et des établissements de santé adoptent largement le modèle du management par objectifs. Les agent·es subalternes des ministères et des hôpitaux publics voient se développer des organisations néotayloriennes très contraignantes. Il apparaît ainsi que les enjeux de la diffusion des techniques de gestion issues des grandes entreprises sont très différents selon la position des agent·es dans les hiérarchies administratives, du fait d’une répartition inégale des marges de manœuvre et des contraintes managériales.
Peripheral Odontogenic Myxoma of Zygoma and Orbital Region - A Unique Case Report with Review of Literature
Authors: Nikunj Anand Mohan , Mishra Biswajit , Elangovan Bathri , Rajkhokar Dilpreet 
Published: May 2024

Abstract

Rationale:
Peripheral odontogenic myxoma (POM) is a rare mesenchymal tumour and it is the first case report of POM involving orbital and zygoma region.

Patient Concerns:
A 16-year-old male presented with a painless, slow-growing swelling over his left infratemporal region.

Diagnosis:
The histopathological examination of the tumour was diagnosed as POM.

Treatment:
The patient was treated by surgical removal of tumour under general anaesthesia.

Outcomes:
The patient has been under follow-up for the past 2.5 years and there has been no recurrence.

Take-Away Lessons:
POM is a rare mesenchymal tumour. To our knowledge, this is only the second report of a POM of the infratemporal region and the first report of a myxoma, which extends into the zygomatic region and lateral wall of the orbit.
The pathological function of neutrophils in pemphigoid diseases
Authors: Matsumoto Daisuke , Amatya Beni , Tsuruta Daisuke , Hiroyasu Sho 
Published: May 2024

Abstract
Pemphigoid diseases (PDs) are a group of autoimmune blistering diseases, including bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, linear immunoglobulin A disease, and other rare variants. These diseases are characterized by the presence of autoantibodies that target proteins at the dermal-epidermal junction, resulting in the formation of tense blisters and erosions on the skin and/or mucosa. The current therapeutic approaches, such as systemic corticosteroid, are associated with significant adverse effects, highlighting that safer and more effective treatment options are an urgent clinical need. To address this unmet need, a comprehensive understanding of the detailed mechanisms underlying PDs is essential. Based on their histopathological infiltration in pemphigoid lesions, neutrophils have long been implicated as major contributors to the initiation and progression of the diseases. Numerous in vivo and in vitro studies have investigated the role of neutrophils in the pemphigoid pathology, revealing various pathological mechanisms induced by these cells, including the release of neutrophil elastase and matrix metalloproteinase-9, as well as the formation of neutrophil extracellular traps. The present review provides a comprehensive summary and critical evaluation of the current understanding regarding the role of neutrophils in PDs. In addition, it discusses the potential of targeting neutrophil-associated pathways as a novel therapeutic approach for the diseases.
Comparison between Calcium Hydroxide with Mineral Trioxide Aggregate and Regenerative Endodontics in Inducing Root Apex Closure during Apexification – A Systematic Review and Meta-analysis
Authors: Gupta Divya , Shaw Amar K. , Mali Sheetal D. , Jadhav Abhijit B. 
Published: May 2024

Abstract
This study aimed to assess better effectiveness between regenerative endodontic procedures (REP) and apexification procedures (AP) with mineral trioxide aggregate (MTA) and calcium hydroxide for inducing root end apex closure. Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were followed and registered in PROSPERO-CRD42023398997. Electronic databases were searched for studies evaluating effectiveness of REP and AP in terms of survival rate, success rate, increase in root length, root width and decrease in apical diameter. Cochrane risk of bias (RoB) -2 tool was used for quality assesssment using RevMan 5.3. The risk ratio (RR) and standardized mean difference (SMD) was used as summary statistic measure with random effect model (P < 0.05). Nine studies were included in qualitative synthesis and eight studies for meta-analysis. Quality assessment revealed moderate to low risk of bias. The pooled estimate through RR and SMD favoured REP being superior to AP for better survival rate (RR = 1.01 (0.96 – 1.06)), success rate (RR = 1.09 (0.96 – 1.24)), increase in root length (SMD = 0.25 (-0.14 – 0.63)), root width (0.66 (0.22 – 1.10)) and decrease in apical diameter (SMD =0.66 (-0.51 – 1.83)). Funnel plot did not show any heterogeneity indicating absence of publication bias. REP significantly improved apical root end closure. AP are equally effective in forming calcific barrier, however it was concluded that regeneration procedures are comparably superior to apexification procedures with greater outcomes. Clinicians should consider employing the REP in cases when root development is severely deficient and where tooth’s prognosis is hopeless even with an apexification procedure.
Hypervitaminosis D Due to Overdose: A Case Series
Authors: Rastogi Shivani , Agarwal Anurag , Bhandari Raj Laxmi , Bagga Aayushi , Tiwari Brihaspati 
Published: May 2024

Abstract
Vitamin D, a fat-soluble vitamin, is found in many animal products and fortified foods and is endogenously made in the human body. Vitamin D supplementation has become a part of the routine prescription; its continuous intake without any follow-up has led to hypervitaminosis D due to overdosing. Hypercalcemia accompanies hypervitaminosis D, affecting bone health, blood pressure, and kidney function. We studied six cases that landed in hypervitaminosis D due to prolonged intake.
Successful Use of Anticoagulation-free Prolonged Extracorporeal Membrane Oxygenation for Massive Pulmonary Hemorrhage in a Child with Heart Transplant and Mechanical Mitral Valve: A Case Report with Review of Literature
Authors: Anton-Martin Pilar , Sandhu Hitesh , Kramer Jennifer , Beasley Gary , Martinez Hugo , Boston Umar S. , Sathanandam Shyam K. , Agrawal Vijay , Chakraborty Abhishek 
Published: May 2024

Background:
Pulmonary hemorrhage is a rare cause of morbidity and mortality in children. Extracorporeal membrane oxygenation (ECMO) can be used as a rescue mode of support in children with life-threatening respiratory failure. However, the dilemma arises as to how to balance anticoagulation to prevent circuit thrombosis while avoiding bleeding complications or worsening hemorrhage.

Clinical Description:
We present an adolescent with a history of Noonan syndrome, orthotopic heart transplant, and mechanic mitral valve that required emergent veno-venous (VV) ECMO support due to life-threatening hypoxia related to severe pulmonary hemorrhage secondary to anticoagulation for his prosthetic mitral valve.

Management and Outcome:
The patient remained on ECMO for 28 days with no anticoagulation and did not receive any anticoagulant or antiplatelet agents postdecannulation for 4 months despite the presence of a mechanical valve. No thrombotic complications to the mechanical valve or the ECMO circuit occurred.

Conclusion:
Prolonged anticoagulation-free VV-ECMO support may be used as a rescue strategy in patients with massive pulmonary hemorrhage resulting in refractory respiratory failure.
Atypical Presentation of Subacute Sclerosing Panencephalitis in a Child
Authors: Hooda Monika , Shokeen Priyanka , Kumar Brijesh , Singhal Bhawna 
Published: May 2024

Background:
Subacute sclerosing panencephalitis (SSPE) is a rare complication of measles, which emerges long after the initial infection. The diagnosis of SSPE can be challenging, especially when initial presentation is atypical.

Clinical Description:
A 6-year-old boy, apparently healthy previously, presented with a sudden onset of generalized myoclonic jerks with intact cognitive and scholastic skills. Past history revealed that the child had measles infection at 7 months of age. Clinical examination, including memory and intellect assessment, was normal except for the generalized myoclonus.

Management and Outcome:
Diagnosis of SSPE was confirmed with positive antimeasles antibodies and characteristic pseudoperiodic pattern on electroencephalogram. The child was started on standard treatment as per the existing guidelines. However, the child showed marked deterioration over the next 4 weeks with loss of cognition and intellect, causing hopelessness and grief in the family, leading to their self-withdrawal from further treatment.

Conclusion:
This case report describes the importance of considering SSPE as a potential diagnosis in patients with myoclonic jerks but intact cognitive and intellectual function. Furthermore, the case portrays the progressive deterioration and profound emotional impact on the family of child with this disease.