bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review: Faktor Tidak Patuh Minum Obat Pada Pasien Diabetes Melitus
Authors: Mustaqimah Mustaqimah , Saputri Rina 
Published: June 2024

Pendahuluan. Diabetes melitus merupakan penyakit kronis yang memerlukan pengobatan jangka panjang, sehingga kepatuhan minum obat berperan penting dalam keberhasilan terapi yang dijalani. Ketidakpatuhan terhadap pengobatan berkaitan dengan menurunnya keberhasilan terapi jangka panjang, meningkatnya mortalitas, dan peningkatan biaya perawatan.. Tujuan. Tujuan penelitian ini untuk mengidentifikasi faktor – faktor yang menyebabkan ketidakpatuhan minum obat pada pasien Diabetes Melitus. Metode. Metode penelitian yang digunakan adalah Literature review. Pencarian artikel menggunakan database google scholar dan pubmed menggunakan kata kunci kepatuhan (compliances) dan diabetes mellitus. Hasil. Hasil penelitian menunjukkan banyak faktor yang mempengaruhi kepatuhan minum obat pada pasien diabetes melitus. Faktor yang mempengaruhi kepatuhan pada setiap penelitian tidak selalu sama. Hal ini dapat disebabkan karena kondisi lingkungan keadaan sosiodemografi, sosioekonomi, dan budaya setempat. Simpulan. Kesimpulan dari penelitian ini adalah Faktor yang mempengaruhi kepatuhan pasien berupa karakteristik pasien, karakteristik penyakit, obat yang digunakan, dukungan keluarga, dukungan tenaga kesehatan, dan fasilitas pelayanan kesehatan.
Analisa Efektivitas Barrier Terhadap Kebisingan Pada Area Doa “Patung Kristus Raja” Di Maumere, NTT
Authors: Susanto Fadila D Kadijah , Kristian Verano Elias , Redo Modestus , Trisandi Bae Samuel 
Published: June 2024

Kebisingan pada suatu wilayah menjadi perhatian penting dalam sebuah perancangan terutama pada bangunan-bangunan yang lebih diperuntukan sebagai tempat beribadah. Penelitian dilakukan pada salah satu tempat ibadah/doa yang umumnya dilakukan umat katolik di Kota Maumere, yakni patung Kristus Raja. Letak patung Kristus Raja ini berada di pusat kota Maumere. Metode yang dipakai deskriptif-eksploratif dengan menggunakan pendekatan teoritis dan pengukuran dengan alat di lapangan. Hasil menunjukkan bahwa tingkat kebisingan yang terjadi di luar pagar diatas 85 DB (lebih tinggi) bila dibandingkan dengan tingkat kebisingan di dalam pagar (<70 DB). Hal ini dipengaruhi oleh beberapa faktor yakni letak, jarak, material maupun dimensi dari pagar dan vegetasi yang dianggap mampu memberikan pengaruh posistif sebagai barrier kebisingan dari patung Kristus Raja.
Penerapan Pendekatan Arsitektur Biofilik Pasca Pandemi Covid-19 Pada Perancangan Rumah Sakit Tipe C
Authors: Prasetya Dwi Insan , Rolalisasi Andarita 
Published: June 2024

Kediri merupakan wilayah pada pada provinsi jawa timur yang terdiri dari kota dan kabupaten dimana setelah pandemi berakhir terdapat data bahwa kebutuhan bed to population ratio (BTR) belum memenuhi standard WHO yaitu 5: 1000 sedangkan di wilayah kota kediri masih di angka perbandingan 3.75:1000 untuk itu perlu dibangunnya fasilitas Kesehatan. Perancangan Rumah Sakit Type C di Kota Kediri merupakan wujud upaya untuk mengatasi masalah tersebut.Metode pembahasan yang di terapkan pada karya tulis ilimiah ini merupakan Metode Studi Litelatur dimana ini menjadi sumber utama pada karya tulis ini. Sedangkan dalam proses perancangan yang beraku akan menggunakan Aturan baru perancangan rumah sakit pasca pandemi Covid-19 dipadu dengan pendekatan Arsitektur Biophilic dimana pendekatan ini memungkinakan manusia hidup berdampingan langsung dengan kesehatan lingkungan, tempat yang dapat meredakan stress, melalui megimplementasikan unsur alam pada desain. Hal ini tentunya dapat membantu pasien dalam pemulihan kondisi pasien yang didapat dari efek lingkungan sehat. Banyak hal yang dapat diterapkan pada pendekatan arsitektur biophilic dengan menyajikan taman yang asri, penambahan tanaman rambat di beberapa dinding rumah sakit, Penataan pencahayaan alami juga diperlukan untuk menciptakan pencahayaan yang tidak terlalu terang ataupun terlalu gelap, dibagunnya taman dalam dengan berbagai bunga warna-warni yang dapat membantu proses pemulihan penderita penyakit penglihatan.
Kajian Implementasi Konsep Rumah Tumbuh Menggunakan Sistem Prefabrikasi Di Dunia Konstruksi
Authors: Marzuki Zulkarnain , Purwanto L.M.F. 
Published: June 2024

Dalam proses penggunaannya rumah selalu mengalami pertumbuhan baik secara horizontal maupun secara vertical, hal ini karena adanya kebutuhan ruang baru akibat bertambahnya anggota keluarga. Pertumbuhan rumah tinggal yang dilaksanakan selayaknya tidak membongkar komponen struktur konstruksi bangunan existing dan juga tidak mengurangi kualitas kenyamanan rumah tinggal, ini merupakan permasalahan dasar yang ditemukan. Sehingga untuk menghindari kedua hal itu perlu adanya suatu metode pertumbuhan rumah yang direncanakan sejak awal, sehingga konsep rumah tumbuh yang direncanakan sejak tahap perancangan perlu dikembangkan. Dan tujuan penelitian ini adalah mencari GAP penelitian sebelumnya untuk mendapatkan novelty yang dapat diterapkan pada konsep rumah tumbuh kedepan. Penelitian ini dilakukan dengan metode penelitian tinjauan literatur yaitu pendekatan sistematis yang digunakan untuk menyelidiki dan menganalisis literatur atau kajian yang berkaitan dengan penggunaan sistem prefabrikasi dalam konteks rumah tumbuh. Ada beberapa aspek yang didapat dari hasil kajian dan menjadi rekomendasi tambahan pada penulisan ini yaitu, penerapan prefabrikasi persegmen, kolom dan balok yang dapat dikembangkan, aksesbilitas supply material dan sirkulasi pekerja, arah bukaan dan sistem utilitas. Dengan mempertimbangkan aspek-aspek ini, implementasi konsep rumah tumbuh menggunakan sistem prefabrikasi dapat mencegah pembongkaran ketika tahap pelaksanaan pengembangan dan mencegah menurunnya kualitas kenyamanan rumah tinggal dari aspek termal dan visual.
Peran Arsitektur Digital Pada Bangunan Ramah Lingkungan
Authors: Khuluk Nazaruddin , Purwanto L.M.F. 
Published: June 2024

Penelitian ini membahas peran penting arsitektur digital dalam mempromosikan keberlanjutan bangunan melalui penerapan Building Information Modeling (BIM), simulasi energi, penggunaan material berkelanjutan dan penggunaan Internet of Things dalam pemantauan lingkungan. BIM menjadi landasan kolaborasi efektif antara pemangku kepentingan dalam tahap perencanaan dan konstruksi dan simulasi energi memberikan perspektif yang mendalam terhadap efesiensi energi bangunan. Penelitian menggunakan metode kualitatif dengan pendekatan teoritis tentang konsep arsitektur digital dan bangunan ramah lingkungan. Hasil penelitian menunjukan bahwa pemilihan material berkelanjutan menjadi fokus khusus dalam meminimalkan dampak ekologis, dan integrasi IoT memungkinkan pemantauan real-time untuk optimalisasi kinerja keberlanjutan.
Implementasi Bentuk Wakul Boran Dengan Pendekatan Analogi Pada Perancangan Fasilitas Budaya Boranan Kabupaten Lamongan
Authors: Syafi'uddin Muhammad Rizqi , Soemarwanto Dadoes 
Published: June 2024

Berbagai kesenian tradisional yang sesungguhnya menjadi aset kekayaan kebudayaan nasional salah satunya kabupaten Lamongan, salah satunya budaya boranan di Kabupaten Lamongan, pada tahun 2023 tari Boran yang berhasil meraih rekor MURI pagelaran tari yang diikuti 1.569 pelajar dan
4.540 porsi nasi boran didasarkan pada filosofi tahun hari jadi Lamongan yakni di tahun 1.569 M, yang saat ini tepat berusia ke 454. Selain itu tari boran juga mampu meraih penghargaan di tingkat provinsi maupun nasional. Kesenian tari boran tidak lepas dari kuliner nasi boran, kuliner nasi boran merupakan makanan khas Kabupaten Lamongan yang sudah ada sejak lama di Kabupaten Lamongan. Kemudian bagaimana solusi agar budaya boranan agar lebih dikenal lebih luas lagi dan mampu menjadi destinasi wisata di kabupaten Lamongan. Tujuannya menciptakan atau merancang fasilitas yang mampu memfasilitasi dan mampu mempresentasikan budaya boranan. Penelitian ini menggunakan metode deskriptif yang dilakukan dengan mengumpulkan data secara kualitatif. Hasil penelitian perancangan fasilitas budaya boranan, menggunakan konsep feminisme and culture dengan pendekatan analogi langsung untuk mengangkat budaya lokal khususnya budaya boranan dalam bentuk arsitektural yang mampu memrepresentatifkan budaya boranan dan mampu menjadikan budaya boranan sebagai destinasi wisata di kabupaten Lamongan.
Role of Nano Enzyme in Diagnosis, Prognosis and Treatment of Gastrointestinal Tract (GIT) Cancer
Authors: Shuja Arslan , Abubakar Muhammad , Shahbaz Muhammad Nasir , Shahid Samiah , Mukhtiar Muzamil 
Published: June 2024

Background:The most common life-threatening problem in population is gastrointestinal tract (GIT) cancer and its mortality rate is very high. Now a days Nanotechnology is a modern way of diagnosis and treatment. Nano-enzymes showed best diagnosis efficacy of treatment and disease progression
Aims and objectives: The aims and objectives of current review were a comprehensive overview of Nano-enzymes in the diagnosis, prognosis, and treatment of gastrointestinal tract cancer.
Practical Implications:Through Nano-enzymes different types of cancer may be diagnosis, prognosis, and treated. While the treatment of gastrointestinal tract cancer with Nano-enzymes showed best results. In this review, we outlined the many types of nanoparticles used to treat esophageal cancer.
Conclusion:A common gastrointestinal cancer with a poor prognosis and a high fatality rate is esophageal cancer. Despite the development of multiple therapy approaches, patients with esophageal cancer still have a low 5-year survival rate. Traditional methods of delivering anti-cancer medications have some drawbacks, including no targeted administration and general toxicity. For the treatment of Esophageal cancer, nanoparticles offer a viable platform for drug delivery since they have a number of outstanding benefits, including less side effects, a longer circulation duration, and a preference for accumulating at the tumor site. These include polymers, micelles, liposomes, inorganic nanoparticles, and organic nanoparticles. In this review, we outlined the many types of nanoparticles used to treat esophageal cancer.
Performance of Melia composita Willd. Seedling in Root Trainers under Two Different Growing Conditions
Authors: Singh Gurwinder , Kaur Aparjot , Bedi Seema , Chauhan Sanjeev Kumar 
Published: June 2024

Melia composita Willd. syn M. dubia Cav. commonly known as Bakayan is a fast growing tree occurring in tropical forests and commercially valued for its multifarious uses. Present investigation was conducted to assess the performance of Melia composita Willd. seedling in two growing environments viz. nursery under tree shade and agro net shade house. Five different types of containers viz., root trainers of size 150 carrying capacity (cc), 200cc, 250 cc, 300cc and poly bags (17x13cm) were used to grow seedlings in comparison to bed grown seedlings. The seedling growth parameters such as, plant height, collar diameter, root length, total fresh/dry weight and root: shoot ratio was recorded for each treatment. Presently, significant interaction among container type, size and growing environment has been observed. Plants attained maximum height, collar diameter, root length, fresh and dry biomass and dry root/shoot ratio under agro net house environment. Total plant biomass was recorded maximum in bed nursery but the root: shoot ratio and sturdiness quotient were least. Root: shoot ratio on dry weight basis and sturdiness quotient was recorded maximum in 300cc root trainer.
Cluster Analysis in Fodder Oats (Avena sativa L.)
Authors: Reddy Annem Sethuvardhan , G. Gayathri , Reddy Amaranatha 
Published: June 2024

Oats is an important crop used globally for food and fodder, holding significant economic value. In the context of livestock farming, fodder oats (Avena sativa L.) is an important crop during winter season. A comprehensive analysis of thirty oat genotypes was conducted at The Regional Agricultural Research Station at Ambalavayal in Wayanadan Eastern Plateaux of Kerala to identify superior genotypes that could increase forage production and improve nutritional quality during the Rabi season of 2022-23. A cluster analysis using Mahalanobis D2 statistics was performed employing the Tocher method within the Indostat software, involving eleven morphological and six nutritional traits. The thirty genotypes were categorized into seven clusters based on their D2 values using the Euclidean method. Cluster I consisted of 14 genotypes (OL-1942, OL-1944, OL-1980, OL-15, OL-212, OL-11, OL-1952, OL-1874-1, OL-1975-2, OL-1976-1, OL-12, OL-1967, AVT-1, OL-13), followed by Cluster II with 8 genotypes (OL-10, OL-2000, OL-1977, OL-1964, OL-1988, OL-1896, OL-1802, OL-1974). Cluster IV comprised 3 genotypes (OL-1937, OL-1963, OL-125), Cluster III included two genotypes (OL-9, JHO-822), and Cluster V(OL-1931-1), VI(OL-1969), and VII(OL-1949) each had one genotype. The inter-cluster D2 values were found to be higher than the intra-cluster D2 values implying that there is a substantial amount of diversity among the genotypes under study with respect to the considered characters. The highest intra-cluster distance was observed in Cluster IV (42.81), followed by Cluster II, Cluster I, and Cluster III. The maximum inter-cluster D2 values were observed between Clusters IV and VII (102.31), and the minimum was observed between Clusters II and V (45.44). Based on the cluster mean, Cluster III was observed to be a significant contributor of days to first and 50% flowering, days to maturity, crude fibre content, total phenolic and antioxidant content. Cluster IV was a potential contributor to green fodder yield, dry matter yield, leaf and stem dry weight, plant height, and phytate content. Cluster V was associated with the number of tillers and crude protein content. Cluster VI was related to the number of leaves and condensed tannin content. Cluster VII was pertaining to the leaf-stem ratio.
Global Diversification of Tilapia Production Techniques: Recent Overview- part 1
Authors: Samaddar Ayan , Ghosh Tapas , Verma Durgesh Kumar 
Published: June 2024

Tilapia secure a bright position in finfish production worldwide because of their excellent flesh quality, disease resistance as well as the capacity to survive in a variety of farming systems and environmental circumstances. They hold a promising position in the propagation of aquaculture in developing countries because the culture is easy, farmers are friendly, and minimum infrastructure is required for their culture. Although more than 70 tilapia species, only three are commonly cultivated: Oreochromis niloticus, Oryza mossambicus, and Oryza aureus, where Nile tilapia contributing about 75% of the total production of tilapia. accounts for approximately 8.3% of the total aquaculture production. These three species grow rapidly under diverse environmental conditions and are able to adapt to different culture systems. These qualities have made them a natural choice for freshwater aquaculture to address food security and the requirement of dietary protein in several developing countries in Asia. However, prolific breeding results in productivity loss, the non-availability of quality seeds, and improper management strategies, which have hindered their cultivation and adoption worldwide for many decades. These problems have been resolved to a large extent in recent years through the introduction of innovative and improved culture practices, better farm management strategies, and the introduction of hormonal and selective breeding techniques. This review explores how tilapia production has increased through the diversification of cultural focused techniques under diverse climatic conditions, infrastructure facilities, and the application of modern tools. Advanced genetic tools and polyculture opportunities could serve as the main target areas to provide maximum efforts for sustainable outcomes.
Lighting the Path: Evaluating Light-Emitting Diode Therapy Versus Salicylic Acid Peel for Inflammatory Acne- A Case Series Analysis
Authors: MLG Diogo, , FGM Carvalho, , RCS Santos, , LF Dourado, , SP Matuck, , KPS Fernandes, , C Pavani, , LJ Motta, 
Published: June 2024

Aims: This study aims to assess the efficacy of red, blue, and combined red-blue light therapy versus 20% salicylic acid peel in treating Grades 2 and 3 inflammatory acne.
Study Design: Cases studies.
Place and Duration of Study: Universidade Nove de Julho, Universidade Adventista de São Paulo, São Paulo Brazil. Between March 2022 from April 2024.
Introduction: Acne is an inflammatory disorder that occurs in the pilosebaceous follicles and deeply affects the self-esteem and quality of life of individuals. Conventional treatments usually produce side effects and promote antibiotic resistance. Light therapy has emerged as a promising modality in clinical and scientific realms for acne management. This study aims to evaluate the effectiveness of red, blue and combined red-blue light therapy versus 20% salicylic acid peeling in the treatment of inflammatory acne grade 2 and 3.
Methodology: We divided 20 participants into four groups who used a mask of LEDs. Group 1 used a mask with blue light (470nm), group 2 used a mask with red light (660nm), group 3 used a mask with red (660nm) and blue (470nm) lights combined in the same device. The groups that used the LED masks received the treatment 3 times a week for 30 days, totaling 12 sessions. Group 4 was submitted to two sessions of salicylic acid peeling at 20%, every 15 days.
Results: Blue light (group 1) showed an improvement of 28.40% in the general skin condition. Group 4 of salicylic acid peeling had an improvement of 28.37%. The combined red and blue light group had an improvement of 26.43%, while the red light showed an improvement of 10.97%.
Conclusion: Based on the series of cases presented, all groups showed improvement, but blue light showed higher results than red light and salicylic acid. However, studies with a larger number of participants should be performed and the ideal parameters for Led use in inflammatory acne should be discussed.
A novel KIF11 mutation in a Turkish patient with microcephaly, lymphedema, and chorioretinal dysplasia from a consanguineous family
Authors: Hazan Filiz , Ostergaard Pia , Ozturk Taylan , Kantekin Esin , Atlihan Fusun , Jeffery Steve , Ozkinay Ferda 
Published: May 2012

AbstractMicrocephaly–lymphedema–chorioretinal dysplasia (MLCRD) syndrome is a rare syndrome that was first described in 1992. Characteristic craniofacial features include severe microcephaly, upslanting palpebral fissures, prominent ears, a broad nose, and a long philtrum with a pointed chin. Recently, mutations in KIF11 have been demonstrated to cause dominantly inherited MLCRD syndrome. Herein, we present a patient with MLCRD syndrome whose parents were first cousins. The parents are unaffected, and thus a recessive mode of inheritance for the disorder was considered likely. However, the propositus carries a novel, de novo nonsense mutation in exon 2 of KIF11. The patient also had midline cleft tongue which has not previously been described in this syndrome. © 2012 Wiley Periodicals, Inc.
Grafting modification of electrospun polystyrene fibrous membranes via an entrapped initiator in an acrylic acid aqueous solution
Authors: Tao Ran , Zhu Xinsheng , Zuo Yu‐Ting , Fan Li‐Juan , Wang Bing , Xin Ji‐Ting 
Published: May 2012

AbstractUltrafine electrospun polymer fibers, with their large specific surface areas, have not found wide applications partly because the fiber surfaces usually carry an insufficient quantity of active groups. The electrospinning and surface‐grafting copolymerization of polystyrene fibrous membranes were carried out via the embedded radical initiator approach. The results from X‐ray photoelectron spectroscopy show that the initiator added to the polystyrene dope was deliberately expelled onto the fiber surfaces. The microstructure and hydrophilicity of the grafted membranes were investigated with Fourier transform infrared spectroscopy, scanning electron microscopy, and water contact angle and water uptake capacity measurements. An increase in the initiator dosages led to decreases in the grafting rate, water uptake, and hydrophilicity of the grafted membranes; the opposite was true for increases in the neutralization of acrylic acid (AA). However, the grafting, water uptake, and hydrophilicity of the grafted membranes presented nonlinear relationships with the concentration of AA. The initiator emigration technique will provide a facile and feasible platform for the surface‐grafting modification of electrospun membranes. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Sulfonated polyimide/chitosan composite membrane for vanadium redox flow battery: Membrane preparation, characterization, and single cell performance
Authors: Yue Mingzhu , Zhang Yaping , Wang Lei 
Published: May 2012

AbstractA novel sulfonated polyimide/chitosan (SPI/CS) composite membrane was prepared from self‐made SPI (50% of sulfonation degree) through an immersion and self‐assembly method, which was successfully applied in vanadium redox flow battery (VRB). The proton conductivity of SPI/CS composite membrane is effectively improved compared to the plain SPI membrane. The VO2+ permeability coefficient across SPI/CS composite membrane is 1.12 × 10−7 cm2 min−1, which is only one tenth of that of Nafion® 117 membrane. Meanwhile, the proton selectivity of SPI/CS composite membrane is about eight times higher than that of Nafion® 117 membrane. In addition, the oxidative stability SPI/CS composite membrane is superior to that of pristine SPI membrane. The VRB single cell using SPI/CS composite membrane showed higher energy efficiency (88.6%) than that using Nafion® 117 membrane, indicating that SPI/CS composite membrane is a promising proton conductive membrane for VRB application. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Development and evaluation of a novel dosage form of diltiazem HCl using ethylene vinyl acetate copolymer and sodium starch glycolate (in vitro/in vivo study)
Authors: Al‐Nimry Suhair S. , Alkhamis Khouloud A. , Ibrahim Hussein G. , Salem Mutaz S. 
Published: May 2012

AbstractThe work aims at developing a CR formulation, with high encapsulation efficiency of diltiazem HCl, suitable for twice daily administration. Microparticles, using EVA copolymer, were prepared by coacervation‐phase separation technique, subjected to controlled extraction and vacuum freeze drying processes to generate and immobilize a non uniform initial drug concentration distribution, and evaluated in vitro and in animals. Effects of increasing initial drug concentration, varying polymer system, increasing porosity, and decreasing tortuosity, varying the size of the microparticles and the pH of the dissolution medium on the release rate were evaluated. The results indicated that the release rate from microparticles was constant (zero‐order) for an appreciable period of time but it was low for twice‐daily administration. It increased with increasing initial drug concentration, varying polymer system, increasing porosity, and decreasing tortuosity, and decreasing the size of the microparticles but the duration of constant release was shorter except for formulations containing 2.00 and 2.25% sodium starch glycolate. 10‐h duration of constant release was achieved and the zero‐order release rate was within the required rate to achieve the desired therapeutic level. The pH of the dissolution medium did not have any effect on the release rate. The results of the in vivo study indicated that in vitro dissolution correlated well with in vivo AUC0‐10 and that there were no statistically significant differences in AUC0‐10 and Cmax between the new CR formulation and Cardizem® CD. Accordingly, a new CR formulation that delivers diltiazem HCl at a constant rate, suitable for twice daily administration was developed. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013