bluuebunny/crossref_metadata_2025_split huggingface dataset:
P03-295 - Paracetamol As The Major Contributing Factor In Parasuicides In A Single Centre In Malaysia
Authors: Kaur A. , Thanasan S. , Ng C.G. , Zainal N.Z. 
Published: June 2010

IntroductionParacetamol is one of the most frequently used drugs in intentional overdoses. Countries that limit the quantity of paracetamol available in a single purchase generally report lower rates of paracetamol related morbidity and mortality.ObjectivesTo determine the socio-demographic characteristics of those who intentionally overdosed on paracetamol and associated psychiatric illness (identifying high-risk groups).AimsTo improve mental health care delivery and propose a restriction of pack sizes of paracetamol in a single purchase.MethodsThis study was a retrospective, descriptive analysis study. Cases of parasuicide in the year 2008 were identified through our database and their case notes studied by completing questionnaires pertaining to details of the act.ResultsOf the 437 cases of parasuicide, 195 cases overdosed on paracetamol (44.6%). Indians made up 41.0% of cases, followed by Malays (31.8%) and Chinese (20.5%). Of the Malays, 63.3% overdosed on paracetamol, compared with other means of parasuicide. 72.8% of those who overdosed with paracetamol were female, 54.4% were single and 69.7% purchased paracetamol over the counter. With increasing age, the incidence of paracetamol overdose declines, being highest (55.2%) in the age group 16-25. Of those who overdosed on paracetamol, 46.2% had a diagnosis of adjustment disorder, 26.2% of acute stress reaction and 21.0% of depression. 42.1% of them had a history of paracetamol overdose.ConclusionsParacetamol continues to be commonly used in parasuicides. Legislation restricting pack sizes of paracetamol in a single purchase is the most pragmatic means of reducing paracetamol related parasuicides and suicides.
P03-302 - Evaluation Of Suicidal Behaviour And Depression Among Nursing Students In Northern Greece
Authors: Papazisis G. , Melissa-Halikiopoulou C. , Tsiga E. , Khachatryan R. 
Published: June 2010

IntroductionSuicide has become a leading cause of mortality and morbidity in adolescents and young adults worldwide and has been identified as one of the key mental health problems affecting students. The aim of our study was to determine the prevalence of depressive symptoms and suicidal ideation among nursing students in Greece.MethodsA total of 142 nursing students of the Department of Nursing of the Technological Educational Institute of Thessaloniki agreed to participate in the study. The Beck Depression Inventory II (BDI-II) was administered. Question 9 of the scale was evaluated to examine suicidal tendency.Results43.9% of the students experienced depressive symptoms. The mean scores on the BDI were higher in year 1 and 3, while the lowest score was observed in year 2. The evaluation of suicidal ideation per year of studies indicated that the percentage of students who thought of suicide but wouldn’t commit it were mainly in the first or in the last (graduate) years. 88% of our total sample reported never having thoughts of suicide. Significant differences on the basis of gender were observed concerning suicidal thoughts, without actually carrying it out (males>females).DiscussionThe stressors in nursing education have been consistently acknowledged in the literature. In our sample can be assumed that 2nd year students are more adjusted to the demands of their studies and appear more confident about their choice. Higher levels observed in the last study years are maybe the result of student worries about their professional future.
P03-306 - Blood Alcohol Concentration In Suicide Victims
Authors: Razvodovsky Y. 
Published: June 2010

BackgroundSuicide is one of the leading external causes of death worldwide. The alarming increase in the occurrence of suicide in Belarus in recent years has resulted in the country having one of the highest suicide rates in the world. It is well recognized that both acute and chronic alcohol use are among the major behaviorally modifiable factors that are associated with suicidal behavior. Several studies have reported relatively high proportion of suicide cases positive for blood alcohol concentration (BAC).AimsThe present study was designed to collect data on BAC-positive suicides in Belarus.MethodThis study was based on the official autopsy reports of the Bureau of Forensic Medicine. The sample consisted of 1135 male subjects (76.3%) and 356 female subjects (23.7%).ResultsIn the present study 61% of males and 30.6% of females were BAC-positive at the time of death. It should be noted that the proportion of BAC-positive suicide in Belarus is among the highest in the world. Positive blood alcohol cases were found more frequently in men age 30-59 (66%) and women age 19-39 (48%). The average BAC was 2.2 ± 0.004 g/dL for males and 2.1 ± 0.005 for females.ConclusionsIn this study, substantial percentages of suicide victims tested positive for alcohol. These results are consistent with previous studies suggesting that acute alcohol intoxication may function as an important effect modifier to the act of suicide. The outcome of this study also suggests that alcohol-related suicide is mainly a male phenomenon.
P03-309 - Suicide Risk And Marital Status
Authors: Roskar S. , Podlesek A. , Kuzmanic M. , Demsar L. , Zaletel M. , Marusic A. 
Published: June 2010

ObjectivesDifferent types of marital status are associated with elevated/decreased suicidal risk.The aim of this research was to study marital status change and the effect of its recency in relation to suicidal behaviour.MethodSuicide victims (1614) in Slovenia and matched controls (4617) were compared for incidence and recency of marital status change during the last five years in their lives.Results10.7% of suicide victims have had a marital status change in the last 5 years as compared to 5.6% of the controls. Becoming widowed and getting divorced proved to be a risk factor for suicidal behaviour. 45,7% of all marital status changes in suicide victims occurred in the last year prior to suicide, whereas marital status changes in the control group were equally distributed over the five years. Recency of marital status change significantly affected suicide risk in interaction with age and type of change: The increase in the risk was much higher for recently married than for the recently divorced or widowed people.ConclusionsBecoming widowed or divorced represents a risk factor for suicidal behaviour. The first year after the change is critical for elevated suicidal risk, in particular for the supposedly positive change of getting married.
P03-313 - Art And Suicide
Authors: Zambrano D. , Tajima-Pozo K. , Padilla J.M. , Anta-Tejado L. , Negueruela M. , Di Stasio E. , Alvarez R. , Lopez Castroman J. 
Published: June 2010

IntroductionSuicide is a major public health problem, one of the leading causes of death and one of the first causes of years of life lost. It is a voluntary act that can be carried out by men and women, children and adults, rich and poor, people of every race and religion.ObjectivesThe aim of this text is to outline the most popular suicides and briefly discuss the representation of suicide in art. Painters such as Vincent Van Gogh, Edvard Munch, Jackson Pollock, musicians as Kurt Cobain, Jim Morrison, Janis Joplin, Jimi Hendrix, the actresses Lupe Vélez, Carole Landis, Pier Angeli, Capucine, Marylin Monroe, Lucy Gordon and the actors Heath Ledger and Freddie Prinze decided the end of their lives in different ways and at different stages.In the literary field, we find the world renowned suicides of Socrates, Seneca and Caton. Other famous and more recent suicidal writers are Ernest Hemingway, Dylan Thomas, Virginia Woolf, Yukio Mishima, Alfonsina Stormi and Cesare Pavese among others.ConclusionSuicide has been represented in several plays and operas, not only people of flesh and blood kill themselves but also fictional characters. the love-death of Liu in Turandot and Tosca in the opera of the same name Are noteworthy, both were composed by Giacomo Puccini. In Hamlet, tragedy written by William Shakespeare, is Ophelia who dies drowning at the sea.
P02-372 - Social And Demographic Factors And Severity Of Symptoms Of Posttraumatic Stress Disorder In Victims Of Intimate Partner Violence
Authors: Araszkiewicz A. , Dabkowska M. 
Published: June 2010

Intimate partner violence (IPV) has been recognized as a prevalent social problem and a source of mental health problems for women. The most common psychiatric difficulty in battered women is posttraumatic stress disorder (PTSD). The aim of this study was to assess the prevalence and intensity of posttraumatic stress disorder among a group of victims of intimate partner violence, as well as the association between some socio-demographic factors and increased risk to develop posttraumatic stress disorder (PTSD).Research method1.Diagnosis and a degree of intensification of PTSD were based on C.G. Watson's at al. PTSD-Interview.2.Semi-structured interview was completed by 104 women to assess risk factors of PTSD (social, demographic and clinic).The examined group consisted of 104 women at the age between 18 and 68 years, the average age 40,8 years; dwelling in the shelters for single mothers and domestic violence victims and out-patients of psychiatric ambulatory.Results75,6% of women who are victims of interpersonal violence had significant, very significant or extreme increase of occurrence of PTSD symptoms. PTSD severity was associated with lower level of education and sexual violence.ConclusionVictims of interpersonal violence are inherently at risk of PTSD. Lower level of education and sexual type of interpersonal violence are risk factors of severity PTSD.
P02-374 - Comparative Of Maternal Health And Reha Of The Mothers With Low Birth And Premature Infant In Hospitals Of Isfahan
Authors: Dabirzadeh S. , Kermani S.A.M. , Kermani S. , Kermani S.A. 
Published: June 2010

IntroductionThe future of a society depends on children's health. Children's growth and health is directly influenced with mother's health. This study has targeted on defining and comparison of maternal health of mother's with low birth and premature with the one of mothers with term infants.MethodsThis descriptive analytic study was carried out on 200 mothers with low birth and premature infants selected by target focused sampling. The date we are collated related to maternal health concerning weight, age, smoking, taken drugs pre delivery weight, times of pregnancy, anxiety due to crisis and maternal health care.ResultsThe findings related to frequency distribution of maternal health of mothers with low birth and premature infants compared with the ones with term infants showed that there was a significant difference between mothers with low birth and premature infants in age group of 15 to 19 years of age and mothers with term infants aged between 20 to 24 years.The findings related to mothers weigh before pregnancy showed that there was not a significant difference between most of the mothers with low birth and premature infants aged between 45 to 54weight years and mothers with term infants of birth than105kg (P< 0/01,). Regarding maternal health in both groups there was a significant difference between taken drugs and duration and dosage, maternal health and anxiety and restlessness.ConclusionsMothers play a major role in care of children and their own mental health influences their children physical and mental health.
P02-377 - Antidepressants And Group Psychosocial Treatment For Depression: An Rct From A Low Income Country
Authors: Husain N. , Chaudhry N. , Fatima B. , Husain M. , Amin R. , Chaudhry I.B. , Rahman R.U. , Haq S.U. , Jaffery F. , Creed F. 
Published: June 2010

BackgroundDepression is a global public health problem with highest rates in women in low income countries including Pakistan. There are no treatment trials from such countries comparing the efficacy of antidepressant treatment with a group psychological intervention.MethodsWe conducted a preliminary RCT in an urban primary care clinic in Karachi, Pakistan. Consecutive eligible women scoring > 12 on the CIS-R and > 18 on HDRS (n=66) were randomly assigned to antidepressant or group psychosocial treatment. The primary outcome measure was HDRS score; secondary outcome measures were disability and quality of life.Results96% patients were assessed at 3 & 6 months after baseline. At 6 months response (50% reduction of HDRS score) occurred in 20 (60.6%) and 22(66.7%) of the psychosocial and antidepressant groups respectively. There was also significant reduction in disability and improvement in health related quality of life in both groups.ConclusionLow costs antidepressants and group psychosocial treatment on the principles of CBT merit further assessment as primary treatments for depression in low income countries.
P02-379 - Profile Of Female Alcoholics
Authors: Krivokapic Z. , Sapic R. 
Published: June 2010

For the past few years increase of psychoactive substances abuse has been recorded. Data show significant increase of female alcoholism.Our research has been directed towards establishing specificity of female alcoholism, meaning personality profile of women with drinking problem.Following was used in the research: interview, questionnaire about basic data, VITI test of intelligence, MMPI, test of ego perception, Benton test and drawing of a human figure. Research was performed on sample of 40 female patients treated in the private clinic in Belgrade, in the period from 2006 to 2008.Following results were achieved by descriptive statistics, and the results have shown what characterises the most a group of female alcoholics: 70% are not married (most of them divorced), 30% is married, 50% are with high school education, and 50% with university education, 65% of the patients describes their childhood as bad, 35% as good. By analysing of the intelligence tests it has been noticed that they are mostly of average intellectual abilities, globally of good abilities of abstract reasoning and mechanical memory, but with weaker abilities of distinguishing important from not important, and with lower social intelligence. Personality and projective tests show social dysfunction with insecurity, suspiciousness, insufficient adaptability, depressive symptomatology, emotional immaturity and instability, egocentrism, feeling of inferiority and guilt.Specificities of clinical picture direct us to further research of female alcoholism. Peculiarities of this sub-population group demand adapted and special preventive and therapeutic forms of work.
P02-381 - Prevalence Of Depression Among Pregnant Women Seen In A Public Primary Health Service In Rio De Janeiro City
Authors: Pereira P. , Abelha L. , Legay L. , Lovisi G.M. 
Published: June 2010

BackgroundDepression is the most prevalent psychiatric disorder during pregnancy and it is associated with psychosocial and clinical obstetric factors. Despite being an important Public Health issue, there are few studies about this subject in Brazil.AimThis study aimed to estimate the prevalence and risk factors for depression during pregnancy.MethodA Cross-sectional study of 331 pregnant women attending a public primary health service over a one-year period in Rio de Janeiro. Participants were interviewed about their socio-demographic status, obstetric/medical conditions, life events and violence during pregnancy. Depression was assessed through the Composite International Development Interview.ResultsThe 12-month prevalence of depression was 14.2% (CI 95% 10.7 - 18.5) and associated factors were: previous history of depression and any psychiatric treatment, unplanned pregnancy, serious physical illness and casual jobs.ConclusionThese data emphasize the need for screening for depression and its risk factors during pregnancy in settings where care is available. Psychosocial interventions and social policies need to be implemented in this population
P02-385 - Sexual Functioning In A Sample Of Serbian Urban Middle-Aged Women - A Pilot Study
Authors: Markovic-Zigic D. , Milicevic-Kalasic A. 
Published: June 2010

objectiveThe of this study was to investigate the determinants of sexuality in a sample of 105 Serbian urban women aged 40-50.MethodsThe sample consisted of 3 groups: menopausal women without therapy; menopausal receiving hormone replacement therapy and non-menopausal women. Measures included Brief Index of Sexual Functioning for Women and Earlier Sexual Functioning Questionnaire. Desire, arousal, activity and satisfaction were compared among groups using χ2 and C coefficient. Variables of special interest in the whole sample were correlated among each other.ResultsNo significant difference between groups was found in basic parameters of sexuality. Communication with partner was the most important factor correlated with basic parameters of sexuality in the total sample. Satisfaction with body image was in significant correlation with sexual desire, while earlier sexual functioning, desire and satisfaction were in negative correlation.ConclusionResults of pilot study suggest that determinants of sexuality in this sample of Serbian middle-aged urban women are psychosocial rather than hormonal. This may be important for clinical practice as well as further studies on female sexual dysfunction.
PW01-04 - Isolation-Rearing Differentially Affects BDNF Levels In Plasma, Hippocampus and Frontal Cortex Of Normal and Genetically Depressed Rats
Authors: Ladurelle N. , Mathé A. , Baulieu E. , Bianchi M. 
Published: June 2010

ObjectivesChanges in mature brain-derived neurotrophic factor (mBDNF) have been associated with the pathogenesis of depression. The present study employed isolation-rearing from weaning in normal Sprague Dawley (SD) and genetically depressed Flinders Sensitive Line (FSL), as a model of gene-environment interaction, to study mBDNF alterations in the plasma, hippocampus and frontal cortex (FC).Methods21-28 days old male SD (n=8) and FSL (n=10) rats were housed in groups or in isolation for 39 days and sacrificed on the last day of housing. The hippocampus and FC were immediately dissected and the trunk blood collected for plasma separation. Pro-BDNF (36 kDa) and mBDNF (14 kDa) were detected in plasma using ELISA and in the hippocampus and FC using Western Blot. The mBDNF data were normalized to those of pro-BDNF to have an accurate index of changes in mBDNF production.ResultsI. Under basal conditions group-housed depressed FSL rats showed significantly (p< 0.05) higher mBDNF in plasma and lower in the hippocampus compared to normal SD rats. No differences were detected in the FC. II. Isolation-rearing in depressed FSL induced a decrease in mBDNF in plasma (p< 0.05) and an increase in the hippocampus (p< 0.01) compared to group-housed FSL, the FC was not affected. In contrast, isolation-rearing did not affect mBDNF in normal SD rats.ConclusionsIsolation rearing differentially affected plasma and brain mBDNF only in depressed FSL rats, supporting the idea that gene-environment interaction is an important factor in determining specific changes in molecular correlates of depression.
PW01-22 - Agomelatine Treatment Reverses Changes in Neuroplasticity Induced by Prenatal Stress in Rats
Authors: Mairesse J. , Morley-Fletcher S. , Zuena A. , Soumier A. , Banasr M. , Casolini P. , Catalani A. , Fagioli F. , Van Reeth O. , Gabriel-Gracia C. , Mocaer E. , Daszuta A. , Nicoletti F. , Maccari S. 
Published: June 2010

The rat model of prenatal restraint stress (PRS) is particularly valuable to study the mechanisms involved in the pathophysiology of anxiety/depression since adult PRS rats show endocrine and behavioral abnormalities that are corrected by antidepressant medication. We have previously shown that agomelatine chronic treatment reversed the anxiety behaviour and decreased hippocampal neurogenesis observed in PRS. Here, we investigated the mechanisms that may contribute to the antidepressant activity of agomelatine, by assessing the effects of a chronic treatment with agomelatine on neurobiological markers of neuroplasticity in the rat hippocampus such as BDNF and its receptor, TrkB, the transcription factor pCREB and metabotrophic glutamate receptors (mGluRs). Adult SD control and PRS rats were treated chronically with agomelatine (40mg/kg ip) or vehicle. 16h after last drug administration, animals were sacrificed and hippocampus dissected for biochemical analysis.PRS animals showed reduced levels of pCREB in the hippocampus and increased hippocampal BDNF, and TrkB receptor levels. Agomelatine reversed changes in pCREB and BDNF/TrkB levels in PRS rats, had no effect on pCREB in control rats, and, interestingly, increased BDNF and TrkB receptor levels in control rats. Moreover, agomelatine reversed the reduced expression (for mGluR5 and mGluR2/3 receptors) and function (for mgluR5 receptor) observed in the hippocampus of PRS rats.In conclusion, we have shown that agomelatine treatment reversed all biochemical and cellular changes induced by PRS in rats. These changes, independently of their direction, are the expression of an enduring maladaptive form of neuroplasticity that may contribute to the depressive/anxious phenotype of PRS rats.
PW01-26 - Fatigue, Sleepiness, Sleep Quality and Their Relationships to Affective Symptom Intensity in Sleep-disordered Patients
Authors: Neu D. , Verbanck P. , Linkowski P. , Le Bon O. 
Published: June 2010

IntroductionImpaired sleep quality and dyssomnia disorders in particular have repeatedly been linked to affective symptoms. However reports about systematic assessments in larger study samples are generally lacking. Furthermore the associative relationships of fatigue and sleepiness complaints to sleep quality and affective symptoms are poorly described.MethodsDuring a one-year period we recruited 570 patients (mean age 28(0.26), 287 males) attending the sleep laboratory of a general University Hospital. Psychometrics were performed using the Pittsburgh Sleep Quality Index (PSQI), the Hospital Anxiety and Depression Scale (HAD), the Fatigue Severity Scale (FSS) and the Epworth Sleepiness Scale (ESS). All patients underwent two consecutive nights of full polysomnographic recording (PSG).ResultsBoth fatigue (FSS) and sleepiness (ESS) were related to affective symptoms (HAD, p< 0.001 and p=0.012 respectively). Fatigue and affective symptom intensity but not sleepiness, were correlated to sleep quality (p< 0.001). The HAD was related to REM-Sleep Latency (HAD, p=0.017). Slow Wave Sleep duration of the second night was negatively correlated to affective symptoms (p=0.21). Body mass index (BMI) was correlated to fatigue (p< 0.001), sleepiness (p=0.18) and to sleep quality (p=0.006) but not to affective symptoms.ConclusionsThese results confirm the tight relations between sleep quality, daytime fatigue or sleepiness and affective symptoms. Residual fatigue is a common and invalidating complaint in mental disorders as major depression. Achievement of clinical remission can be compromised because of residual treatment resistant symptoms. PSG might be useful in certain conditions to rule out co-morbid sleep disorders and to orientate treatment attitudes.