bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perfil de Laboratório Urbano do TUC: Naucalpan, México
Authors: Roll Michael , Romero Magallán Marisol , Ramírez Andrea , Guerra Flávia , Ramos-Galvez Alejandra , Sandholz Simone , Campos-Sánchez Mariana , Zubicaray Gorka , Pozos-Espinosa Óscar Jair , Villasís-Escobedo Andrea , Enríquez-Alcaraz Ana Iris 
Published: May 2024

Depois de dois anos de operação, os desafios e as principais conquistas do Laboratório Urbano do TUC estabelecido em Naucalpan, no México, fornecem lições valiosas para sustentar atividades em andamento, acelerar transformações mais amplas e orientar esforços semelhantes em outros lugares: 1.	RECONHECENDO OS DESAFIOS E BENEFÍCIOS DA FLUTUAÇÃO DE MEMBROS DO LU: Assumindo a existência de um grupo central de membros do LU, mudanças em sua composição são esperadas e frequentemente positivas. Tais mudanças podem inclusive ser planejadas assim que o LU iniciar uma nova fase, por exemplo, ao passar do planejamento para a implementação de ações concretas. Os facilitadores do LU devem apoiar a integração de novos membros para maximizar o benefício de suas novas perspectivas e contribuições para o trabalho em curso do LU. 2.	ABORDANDO A REPRESENTAÇÃO LIMITADA DE MORADORES E DO SETOR PRIVADO: Os processos de participação necessitam de uma metodologia sólida e de pensamento criativo. Mesmo com a melhor das intenções e facilitação adequada, certos grupos ou setores são particularmente difíceis de envolver nos LUs. Isto pode acontecer porque alguns membros do LU expressam preocupações e veem riscos potenciais associados à participação de atores específicos, ou porque tais atores não percebem benefícios ou simplesmente não estão interessados em participar. No futuro, o LU de Naucalpan considerará abordagens e formatos alternativos, inovadores e localmente específicos para incentivar a participação e o engajamento significativo destas partes interessadas. 3.	TRABALHANDO COM PERSPECTIVAS DIVERSAS PARA PROMOVER NOVAS REDES E CONFIANÇA MÚTUA: Ao proporcionar um ambiente para trocas e discussões construtivas de diversas perspectivas, conhecimentos, interesses e opiniões, a abordagem do LU promove novas redes, bem como a confiança mútua e coesão. Isto é particularmente evidente entre a sociedade civil e o governo num ambiente de “baixa confiança no governo”, e proporciona uma base sólida para a ação climática coletiva. 4.	LIDANDO COM A PARTICIPAÇÃO E A DEPENDÊNCIA DE AUTORIDADES PÚBLICAS: Embora a participação e o apoio das autoridades governamentais sejam fundamentais para os LUs, tornar-se excessivamente dependente das mesmas é um risco para a neutralidade dos LUs, para discussões construtivas e para o seu potencial impacto transformador. Para uma boa operação e sustentabilidade dos LUs, e expansão de projetos experimentais, a participação e o apoio do governo devem, portanto, ser cuidadosamente equilibrados com os de outros setores.
Ambiente, saúde e sistemas agroalimentares políticas públicas para o cumprimento do Objetivo de Desenvolvimento Sustentável nº 02 da Agenda-2030 da ONU
Authors: Santos Erivan José dos , Cunha Filho Moacyr , Farias Gleidson Alves de 
Published: May 2024

No ano de 2015 foi apresentado ao mundo um “Pacto Global” o qual surgiu do consenso de 193 países que se reuniram em Nova Yorque com o propósito de elaborar os Objetivos de Desenvolvimento Sustentável-ODS que viessem a ser prioridade para todos os envolvidos, de modo que um desses objetivos tem se mostrado fundamental para o desenvolvimento com mais equidade e justiça alimentar, além de buscar atenuar as mazelas que a desigualdade provoca, como a miséria e a falta de perspectivas para milhões de pessoas em todo o mundo, trata-se do ODS nº 02 é o que representa maior sentido ao termo referente à dignidade da pessoa humana, vez que para se ter dignidade não é o bastante a sobrevivência, mas a existência digna como pessoa e como sujeito de direitos. O Brasil exerce importante papel nessa jornada mundial, pois, temos grande parte de nossas terras agriculturáveis e deveras propícias para o desenvolvimento de sistemas agroalimentares capazes de suprir a necessidade de nossa população, bem como de contribuir sobremaneira para debelar a forma em nações ao redor do planeta, assim, o presente artigo pretende alertar para a importância da concretização de ODS n° 02 da Agenda-2030 da Organização das Nações Unidas, O ODS 2 pretende acabar com todas as formas de fome e má nutrição até 2030, de modo a garantir que todas as pessoas - especialmente as crianças - tenham acesso suficiente a alimentos nutritivos durante todos os anos, o presente artigo está didaticamente distribuído tendo em seu bojo a introdução que visa preparar o leitor para a perfeita compreensão do objeto em deslinde; na sequência vem o desenvolvimento que tem por finalidade abordar de forma mais aprofundada ao cerne da questão aventada e, por fim, tem-se a conclusão como forma de enfeixar toda a discussão promovida neste ensaio, sem desprezar de forma alguma as diversas nuances, que, porventura, deixaram de ser abordadas por questões de ordem meramente práticas e limitadoras, pois, um trabalho de tamanha magnitude não se encerra num artigo por mais que se tenha envidado esforços para tratar da matéria trazida a lume.
Effects of different production systems on health, zootechnical and metabolic parameters in Holstein calves in the extreme south of Brazil
Authors: Teixeira Ritieli dos Santos , Nicola Murilo Scalcon , Sousa Gustavo Felipe da Silva , Londero Uriel Secco , Xavier Eduardo Gularte , Del Pino Francisco Augusto Burkert , Rabassa Viviane Rohrig , Corrêa Marcio Nunes 
Published: May 2024

The aim of this study was to evaluate the incidence of diseases as well as metabolic and zootechnical parameters in Holstein calves maintained in individual or collective housing systems in the extreme south of Brazil. One hundred calves were included immediately after birth and monitored for 90 days. Animals were randomly divided into two groups: individual stalls group (ISG; n=50) and collective stalls group (CSG; n=50). ISG calves were individually housed in 1.2m² wood pens and received 6 L of milk/day and concentrate food and water ad libitum for 90 days. Calves in the CSG were housed in groups of up to 25 animals, in a total of two stalls containing one animal per 3 m2. CSG calves received up to 8 L of milk/day at 0-15 days, milk ad libitum at 15-40 days, 7.2 L of milk. /day at 40-60 days, and gradual weaning at 60-90 days with concentrate food and water ad libitum, using an automatic feeder. In both groups, Zootechnical parameters (weight, thoracic perimeter, height at the withers, and rump width) were measured weekly during the first 28 days and once every 15 days until weaning. Blood samples were retrieved weekly during the first 28 days. Metabolic parameters evaluated in this study were total calcium, beta-hydroxybutyrate (BHBA), free fatty acids (FFA), and glucose. The animals were monitored daily for clinical signs of diseases diarrhea and respiratory symptoms. General morbidity was higher in CSG 92% compared to ISG 74% (p<0.05). We observed increased diarrhea-related morbidity and a higher rate of recurrence in the ISG (50% and 60%, respectively; p<0.05) compared to those in the CSG (both 20%, p<0.05 between groups). The morbidity due to bronchopneumonia was higher in the CSG (92%) than in the ISG (74%, p<0.05). Recurrence of bronchopneumonia and mortality were similar between groups (p>0.05). Glucose, FFA, and BHBA concentrations were higher in the ISG (p<0.05) and total calcium higher in CSG (p<0.05). Finally, the weight and thoracic perimeter were higher in the CSG than those in the ISG, whereas the height and, rump width, at the withers was higher in the ISG than that in the CSG (p<0.05). In conclusion, animals raised in a collective system with automatic feeders exhibited less diarrhea and increased serum calcium as well as improved zootechnical development, although they had a higher incidence of bronchopneumonia.
LC-MS Lipidomic Analysis of Macrophages
Authors: Pražáková Kateřina , Vrkoslav Vladimír , Strnad Štěpán , Muffová Barbora , Kauerová Soňa , Froněk Jiří , Králová Lesná Ivana , Poledne Rudolf , Sýkora David 
Published: May 2024

Currently, an increasing incidence of cardiovascular diseases is observed in the population. Factors contributing to their development are obesity and pro-inflammatory processes occurring in the adipose tissue. Macrophages, cells of the non-specific immune system, which can be divided into pro-inflammatory and anti-inflammatory, play a significant role in these processes. For a better understanding of these phenomena, it is necessary to analyze the lipidome of macrophages of the two mentioned groups. The presented work was focused on the optimization of selected parameters of the LC-MS method for the analysis of 71 lipids from 16 lipid classes. Best results were achieved with column Acquity UPLC BEH C18 (1.7 µm, 2.1 mm × 100 mm) operating at the flow rate of 300 μL min–1 and temperature of 55 °C. The optimal desolvation temperature was 350 °C and the gradient elution started at 0 % of solvent B in the mobile phase. Retention dependencies were characterized for individual lipid classes. They were successfully fitted with a linear model (R2 > 0.99) and subsequently used to confirm the accuracy of lipid identification. The optimized LC-MS method was also used to analyze the real samples of macrophages isolated from the adipose tissue of kidney donors. Samples were provided by Institute for Clinical and Experimental Medicine. The principal component analysis gave insight into the division of macrophages according to their type. The volcano plot showed a significant increase in the concentration of five lipids in the case of pro-inflammatory macrophages.
FACTORS DETERMINING THE EFFECTIVENESS OF INNOVATION ACTIVITIES IN THE CONTEXT OF DIGITAL BUSINESS TRANSFORMATION
Authors: Фуфаев М.Д. 
Published: May 2024

Переход компаний в цифровую среду неизбежно приводит к персонализации запросов их потребителей за счет все большего накопления о них данных. В этой связи роль инноваций для компаний возрастает в разы, а их успешность связана с эффективностью данной деятельности. Целью данной статьи является выявление факторов, которые, определяют эффективность инновационной деятельности российских компаний в условиях внедрения цифровых технологий. Исследование факторов проводилось на примере российских промышленных как крупных, так и средних компаний, поскольку они по данным Росстата обладают одним из самых высоких уровней инновационной активности. Для этого были проанализированы стратегии развития компаний, степень цифровизации отдельных бизнес-процессов, эффективность их инновационной деятельности. Кроме того, были сформулированы некоторые особенности цифровой трансформации российских компаний, осуществляющих инновационную деятельность на основе анализа ключевых проблем цифровизации. По результатам исследования автором была разработана система факторов в привязке к стадиям инновационного процесса и обеспечивающих их ресурсам, которая учитывает особенности указанных компаний. Полученная система факторов, при ее учете в деятельности компании, будет способствовать повышению эффективности инновационной деятельности за счет ускорения всех ее стадий.
The transition of companies to the digital environment inevitably leads to the personalization of the requests of their consumers due to the increasing accumulation of data about them. In this regard, the role of innovation for companies increases significantly, and their success is related to the effectiveness of this activity. The purpose of this article is to identify the factors that determine the effectiveness of innovative activities of Russian companies in the context of the introduction of digital technologies. The study of factors was conducted on the example of Russian industrial companies, both large and medium-sized, as they have one of the highest levels of innovation activity, according to Rosstat. To do this, the company's development strategies, the degree of digitalization of individual business processes, and the effectiveness of their innovation activities were analyzed. In addition, some features of the digital transformation of Russian companies engaged in innovative activities were formulated based on the analysis of key problems of digitalization. According to the results of the study, the author has developed a system of factors related to the stages of the innovation process and providing them with resources, which takes into account the characteristics of these companies. The resulting system of factors, when taken into account in the company's activities, will contribute to improving the efficiency of innovation activities by accelerating all its stages.
ECONOMIC INTERESTS AND MECHANISMS FOR COORDINATING BUSINESS PROCESSES: SEARCHING FOR AN ALTERNATIVE DIRECTION OF RESEARCH
Authors: Бирюков Е.В. 
Published: May 2024

Целью статьи является обоснование исследовательского подхода к построению теории экономической координации бизнес-процессов, учитывающей особенности экономических интересов субъектов и разнообразие моделей экономических взаимодействий. Автором показано, что конкурирующие сегодня направления научного поиска, базирующиеся на использовании институционально и ценностно ориентированных подходов к анализу связи экономических интересов субъектов и механизмов координации бизнес-процессов, являются концептуально ограниченными, что обусловливает создание фрагментированных теоретических описаний. Пересмотр сложившихся концептуальных подходов предлагается проводить исходя из признания двойственной природы субъектов экономики и понимания их как носителей индивидуальных и общественных черт экономической культуры, ценностей, целей и интересов. В связи с этим возникает возможность анализа эндогенных по своему статусу способов координации бизнес-деятельности субъектов, экономические интересы которых выступают проявлением их ценностных представлений. Предложенная исследовательская перспектива ориентируется на переформатирование механизмов координации бизнес-процессов с учетом меняющейся деловой среды в условиях цифровизации экономики на основе формирования баланса экономических интересов всех заинтересованных сторон в соответствии с достигнутым ценностным компромиссом.
The purpose of the article is to substantiate the research approach to the construction of the theory of economic coordination of business processes, taking into account the features of the economic interests of subjects and the variety of models of economic interactions. The author shows that the competing areas of scientific research based on the use of institutional-oriented and value-oriented approaches to the analysis of the relationship between the economic interests of subjects and mechanisms for coordinating business processes are conceptually limited, which leads to the creation of fragmented theoretical descriptions. It is proposed to revise the existing conceptual approaches on the basis of the recognition of the dual nature of economic entities and their understanding as carriers of individual and social features of economic culture, values, goals and interests. In this regard, it is possible to analyze endogenous in their status ways of coordinating the business activities of entities whose economic interests are a manifestation of their value concepts. Proposed The research perspective focuses on the reformatting of mechanisms for coordinating business processes, taking into account the changing business environment in the context of digitalization of the economy based on the formation of a balance of economic interests of all stakeholders in accordance with the achieved value compromise.
PENGARUH PENDAPATAN ASLI DAERAH, DANA BAGI HASIL, DAN DANA ALOKASI UMUM TERHADAP BELANJA DAERAH KOTA JAYAPURA
Authors: Abdul Wahab La Ode 
Published: May 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pendapatan asli daerah, dana bagi hasil, dan dana alokasi umum secara parsial dan simultan terhadap belanja daerah Kota Jayapura. Data yang digunakan dalam penelitian ini adalah data realisasi Anggaran Pendapatan dan Belanja Daerah Kota Jayapura Periode 2010-2019. Alat analisis yang digunakan adalah regresi linear berganda. Hasil penelitian ini menunjukkan bahwa pendapatan asli daerah dan dana bagi hasil berpengaruh positif tidak signifikan terhadap belanja daerah Kota Jayapura. Dana alokasi umum berpengaruh positif dan signifikan terhadap belanja daerah Kota Jayapura. Berdasarkan hasil uji simultan, diketahui bahwa pendapatan asli daerah, dana bagi hasil, dan dana alokasi umum berpengaruh positif dan signifikan terhadap Belanja Daerah Kota Jayapura. Hasil koefisien determinasi menunjukkan bahwa pendapatan asli daerah, dana bagi hasil, dan dana alokasi umum memberikan kontribusi yang sangat besar terhadap belanja daerah Kota Jayapura, yaitu sebesar 94,8%. Sedangkan sisanya sebesar 5,2% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
ANALISIS RASIO LIKUIDITAS DAN PROFITABILITAS DALAM MENGUKUR KINERJA KEUANGAN PADA PT. PRODIA WIDYAHUSADA TBK
Authors: Abdul Wahab La Ode , Eriansyah Dwiky 
Published: May 2024

Penelitian ini bertujuan untuk mengetahui kinerja keuangan PT. Prodia Widyahusada Tbk diukur dari rasio likuiditasdan rasio profitabilitas. Jenis penelitian yang penulis gunakan dalam penelitian ini adalah jenis penelitian kuantitatif, dengan menggunakan data laporan keuangan periode 2018-2021. Hasil penelitian ini adalah Rasio likuiditas PT. Prodia Widyahusada Tbk selama tahun 2018 sampai dengan 2021 menunjukkan nilai yang cukup besar. Perkembangan rasio likuiditas PT Prodia Widyahusada Tbk terlihat fluktatif, hal ini terlihat dari nilai current ratio dan quick ratio, dimana pada kedua rasio ini pada tahun 2019 dan 2021 mengamai kenaikan, namun pada tahun 2020 mengalami penurunan. Perkembangan rasio profitabilitas PT Prodia Widyahusada Tbk sejak tahun 2019-2021 cenderung mengalami kenaikan, hal ini terlihat dari nilai net profit margin, return on asset dan return on equty yang setiap tahunnya mengalami kenaikan. Berdasarkan hasil analisis perbandingan nilai rasio keuangan PT. Prodia Widyahusada Tbk dengan nilai standar rasio keuangan perusahaan industri, dapat diketahui bahwa dari sisi likuiditas kinerja keuangan PT. Prodia Widyahusada Tbk tahun 2018-2021 dapat dikategorikan Baik, karena telah memenuhi nilai standar rasio keuangan industri. Sedangkan dari sisi rasio profitabilitas masih dikategorikan kurang baik, karena nilai rasionya masih di bahwa nilai standar rasio keuangan industri.
Analisis Current Ratio dan Profit Margin Untuk Menilai Kinerja Keuangan Pada PT Mayora Indah Tbk
Authors: Sunaryo Agus 
Published: May 2024

Penelitian ini bertujuan untuk mengetahui Analisis Current Ratio dan Profit Margin Untuk Menilai Kinerja Keuangan Pada PT Mayora Indah Tbk. Penelitian ini menggunakan analisa data kuantitatif agar dapat menyelesaikan masalah yang diangkat dalam penelitian ini, khususnya rasio likuiditas dan profitabilias. Hasil penelitian mengungkapkan bahwa hasil pada uji t didapati bahwa 1) Secara umum kinerja keuangan PT Mayora Indah,Tbk berdasarkan rasio current ratio dapat memenuhi kewajiban jangka pendek dan Profit margin dapat menghasilkan laba tetapi hasil dari angka rasio current ratio dan Profit margin dapat dikatakan belum efisien, karena hasil dari current rati dan rasio Profit margin mengalami fluktuasi. 2) Perkembangan current ratio dan profit margin PT Mayora Indah,Tbk belum efisien meskipun mampu memenuhi utang jangka pendeknya dan dapat menghasilkan laba ditiap tahunnnya hal ini dikarenakan perkembangan di setiap current ratio dan rasio Profit margin mengalami fluktuasi dikarenakan asset lancar tidak dikolola secara optimal dan beban-beban belum mampu diminumkan sehingga pendapatan kurang optimal.
Doenças valvares sob a perspectiva do Teste Cardiopulmonar de Exercício: uma revisão integrativa dos últimos 10 anos
Authors: Medina Mariana Sattler Lima , Correia Hanna Vitória da Cruz , Dias Joanne Conceição Martins Aragão Costa , Souza Mylenna Bomfim , Feitosa Roberta Helena Fernandes , Guilhen Carolina Christianini Mizzaci , Campos Milena dos Santos Barros 
Published: May 2024

Objetivo: Avaliar artigos científicos sobre o uso do Teste Cardiopulmonar de Exercício (TCPE) nas valvopatias com insuficiência ou estenose moderada a grave em pacientes oligo ou assintomáticos. Métodos: Trata-se de uma revisão integrativa de literatura, com artigos publicados entre 2014 e 2024, sem restrição linguística, disponíveis online na íntegra. Utilizou-se como questão norteadora: “Quais as evidências sobre a realização do teste cardiopulmonar de exercício em pacientes portadores de valvopatias moderadas a graves e assintomáticos?”. A pesquisa bibliográfica foi realizada através das bases de dados PUBMED/MEDLINE, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Coleção BVS, por meio dos seguintes descritores em Ciências da Saúde (DeCS): Heart Valve Diseases; Cardiopulmonry Exercise Testing, com uso do operador booleano “AND”. Resultados: A amostra final foi composta por 09 artigos que seguiram os critérios de inclusão e exclusão previamente definidos. Considerações finais: O TCPE está bem estabelecido na literatura como uma opção segura, acessível e objetiva, para avaliação dos pacientes com doença valvar, permitindo análise real do condicionamento aeróbico, associado ao comportamento dos sistemas cardiovascular, pulmonar e periférico, trazendo maior precisão da avaliação clínica do paciente.
Comparative and Competitive Advantages of Palm Oil in International Markets
Authors: Nuraini Candra , Helbawanti Octavia 
Published: May 2024

This research aims to (1) Analyze the competitiveness of Indonesian cocoa butter exports in international markets based on comparative advantages. (2) Analyzing the competitiveness of Indonesian cocoa butter exports in the international market based on competitive advantages. The competitiveness of palm oil is analyzed in two ways: comparative advantage analysis and competitive advantage analysis. The approaches used in comparative advantage analysis are RCA, RSCA, and Product Mapping (RSCA and TBI). Meanwhile, the competitive advantage analysis uses the ECI approach. The competitiveness of Indonesian palm oil exports has a comparative advantage (RCA 54.15); based on Product Mapping analysis, Indonesian palm oil is in Group C, which means it has export specialization and has a comparative advantage. The ompetitiveness of Indonesian palm oil exports shows a competitive advantage or an upward trend; the value shows more than one (ECI 1.01).
Firm Size as a Moderating Variable of the Effect of Liquidity and Profitability on Firm Value
Authors: Noni Marliyana  , Hadi Pramono  , Sri Wahyuni  , SEB Santoso  
Published: May 2024

The aim of this research is to determine company size as a moderating variable in the relationship between liquidity and profitability and the value of LQ45 companies from financial reports listed on the Indonesia Stock Exchange for 2020-2022. The sampling method uses purposive sampling to produce 61 companies. The data analysis model uses Moderated Regression Analysis. The results of this research shows liquidity does not affect company value; profitability has a positive effect on company value; in company size is unable to moderate the relationship between liquidity and company value; in company size is unable to moderate the relationship between profitability and company value