bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increasing coverage and uptake of voluntary family planning in Uganda’s emerging municipalities and secondary cities: An implementation research study protocol
Authors: Kananura Rornald Muhumuza , Birabwa Catherine , Ssanyu Jacquellyn Nambi , Kizito Felix , Kagaha Alexander , Namutanba Sarah , Kyangwa Moses , Kakaire Othman , Waiswa Peter 
Published: May 2024

Introduction
While urban areas are often perceived to have better access to healthcare services, including modern family planning (FP) services, urban dwellers including those with better socioeconomic status are faced with multidimensional challenges that shape their access to appropriate FP services. In Uganda’s urban spaces, there is currently a lack of understanding among service providers, civil society organizations, and individuals/communities regarding the implementation of interventions that promote informed choice and voluntary use of family planning services. This knowledge gap has profound implications for reproductive rights. This study seeks to enhance existing efforts towards increasing coverage and uptake of Voluntary Family Planning (VFP) in Jinja City and Iganga Municipality, central eastern Uganda. Our primary question is, “What interventions can effectively be packaged and delivered to increase the uptake of VFP among different segments of urban residents?”

Methods
We propose to use the Human-Centered Design (HCD) approach to understand the needs and challenges of users and community capabilities in ensuring access to VFP services. Co-creating with stakeholders’ engagement and a data-driven-centric approach will steer design and adaptation that respond to the different population segments within the urban space. As such, the study will be implemented in three phases: formative assessment, design and implementation, and implementation monitoring and evaluation. The implementation process will incorporate robust monitoring, learning, and adaptation mechanisms. The primary focus of these mechanisms will be to utilize gathered information effectively to inform the design of the implementation and facilitate continuous learning throughout the process. The study will apply a process monitoring and evaluation approach to address questions related to what package of FP interventions work, for whom, under what circumstances and why.

Discussion
Guided by strong learning and implementation flexibility, we hypothesize that our implementation will provide segmentation-specific high-impact interventions in an urban context.

Registration
This implementation research protocol has been registered on the Open Science Framework (OSF) repository Registries (https://osf.io/vqxu9; DOI: 10.17605/OSF.IO/VQXU9).
The effects of co-designed physical activity interventions in older adults: A systematic review and meta-analysis
Authors: Zacharuk Amanda , Ferguson Alison , Komar Chelsea , Bentley Nicole , Dempsey Alexandra , Louwagie Michelle , O’Hoski Sachi , D’Amore Cassandra , Beauchamp Marla 
Published: May 2024

Background
Physical activity (PA) declines with age despite the knowledge that physical inactivity is a leading cause of disease, death, and disability worldwide. To better tailor PA interventions to older adults, researchers are turning to the collaborative principles of co-design. The purpose of this systematic review was to compare the effectiveness of co-designed PA interventions and standard care for increasing PA and other health outcomes (i.e., physical function, quality of life, mental health, functional independence, attendance and attrition rates) in older adults.

Methods
A search was conducted in MEDLINE, AgeLine, CINAHL, Embase, and SPORTDiscus. Records were screened by independent pairs of reviewers. Primary research studies conducted among community-dwelling older adults (age 60+) comparing co-designed PA interventions to standard care were considered for inclusion. Controls included wait-list control, usual care, sham interventions, PA interventions without the use of co-design, and no intervention. A random effects meta-analysis was conducted, and the standardized mean difference (SMD) was used to report effect estimates. Quality of evidence was rated using GRADE.

Results
Of 16,191 studies screened, eight (N = 16,733) were included in this review. Most studies reported results favouring the effect of co-design on physical activity; however, only two studies (N = 433) could be pooled for meta-analysis resulting in a SMD of 0.28, (95% CI = -0.13 to 0.69; p = 0.19; I2 = 56%) immediately post-intervention. The GRADE quality of evidence was very low. The quantitative analysis of three studies reported improved physical function.

Conclusion
This review did not demonstrate that co-designed PA interventions are more effective than standard care for increasing PA in older adults; however, evidence was limited and of very low quality. Further well-designed trials are warranted to better understand the impacts of co-designed PA interventions and how to best implement them into practice.

Trial registration
PROSPERO registration number:
CRD42022314217.
Determinants of post-acute COVID-19 syndrome among hospitalized severe COVID-19 patients: A 2-year follow-up study
Authors: Elias Tamrat Petros , Gebreamlak Tsegaye Wesenseged , Gebremeskel Tigist Tesfaye , Adde Binyam Lukas , Abie Abraham Sisay , Elias Bitaniya Petros , Argaw Abel Mureja , Tenaw Addis Aschenek , Belay Biruk Mulugeta 
Published: May 2024

Background
Post-acute COVID-19 syndrome is a condition where individuals experience persistent symptoms after the acute phase of the COVID-19 infection has resolved, which lowers their quality of life and ability to return to work. This study assessed the prevalence and associated risk factors of post-acute COVID-19 syndrome (PACS) among severe COVID-19 patients who were discharged from Millennium COVID-19 Care Center, Addis Ababa, Ethiopia.

Methods
A cross-sectional study using data collected from patient charts and a follow-up telephone interview after two years of discharge. Systematic random sampling was used to select a total of 400 patients. A structured questionnaire developed from the case report form for PACS of the World Health Organization (WHO) was used. Frequency and cross-tabulation were used for descriptive statistics. Predictor variables with a p-value <0.25 in bivariate analyses were included in the logistic regression.

Result
Out of the 400 patients, 20 patients were dead, 14 patients refused to give consent, and 26 patients couldn’t be reached because their phones weren’t working. Finally, 340 were included in the study. The majority (68.5%) were males and the mean age was 53.9 (±13.3 SD) years. More than a third (38.1%) of the patients reported the persistence of at least one symptom after hospital discharge. The most common symptoms were fatigue (27.5%) and Cough (15.3%). Older age (AOR 1.04, 95% CI 1.02–1.07), female sex (AOR 1.82, 95% CI 1.00–3.29), presence of comorbidity (AOR 2.38, 95% CI 1.35–4.19), alcohol use (AOR 3.05, 95% CI 1.49–6.26), fatigue at presentation (AOR 2.18, 95% CI 1.21–3.95), and longer hospital stay (AOR 1.06, 95% CI 1.02–1.10) were found to increase the odds of developing post-acute COVID-19 syndrome. Higher hemoglobin level was found to decrease the risk of subsequent post-acute COVID-19 syndrome (AOR 0.84, 95% CI 0.71–0.99).

Conclusion
The prevalence of post-acute COVID-19 syndrome is high, with a wide range of persistent symptoms experienced by patients. COVID-19 survivors with the identified risk factors are more susceptible to post-acute COVID-19 and require targeted monitoring and care in a multidisciplinary approach.
Rod-shaped Mo(vi) trichalcogenide–Mo(vi) oxide decorated on poly(1-H pyrrole) as a promising nanocomposite photoelectrode for green hydrogen generation from sewage water with high efficiency
Authors: Aldosari Eman , Rabia Mohamed , Abdelazeez Ahmed Adel A. 
Published: May 2024

Abstract
The synthesis of rod-shaped Mo(vi) trichalcogenide–Mo(vi) oxide, cleverly adorned on a poly(1-H pyrrole) (P1HP) matrix (MoS3–MoO3/P1HP), is achieved through a one-pot preparation method. This process occurs under the pyrrole oxidation employing the oxidizing agent Na2MoO4. Notably, this oxidation process facilitates the direct incorporation of the inorganic constituents into the polymer matrix. Of particular significance is the material’s bandgap, which is optimally situated at 1.4 eV, rendering it highly suitable for its intended applications. The material assumes a rod-like structure, characterized by an average length of 400 nm and width of 30 nm, further enhancing its desirability. In practice, this thin film serves as an exceptionally promising photoelectrode. It finds its forte in the generation of hydrogen from sewage water, achieving an impressive efficiency rate of 12.66%, specifically at 340 nm. In addition to that, it boasts a remarkable hydrogen generation rate of 1.2 moles·h−1·cm−2. Moreover, the material exhibits remarkable versatility in its response to light. Its sensitivity to monochromatic light across a broad optical spectrum (UV till IR), underscores its potential for hydrogen generation applications for industrial applications.
Association of BDNF polymorphism with gestational diabetes mellitus risk: a novel insight into genetic predisposition
Authors: Chermon Danyel , Birk Ruth 
Published: May 2024

Abstract

Objectives
Gestational diabetes mellitus (GDM) is a prevalent metabolic disorder during pregnancy with potential long-term health implications for the mother and child. The interplay between genetics and GDM susceptibility remains an area of active research. Recently, brain-derived neurotrophic factor (BDNF) was investigated in relation to obesity and impaired glucose metabolism and pathogenesis. We aimed to investigate the association of common BDNF polymorphisms, with GDM risk in Israeli females.

Methods
A cohort of 4,025 Israeli women data for BDNF common SNPs was analyzed for potential association with GDM using binary logistic regressions analysis (SPSS 29.0 and R) adjusted for confounding variables (age, T1DM, T2DM, PCOS) under different genetic models.

Results
The GDM and Non-GDM genetic frequencies for the BDNF rs925946 Tag-SNP were significantly different. The genetic frequencies were 54.16 %, and 66.91 % for the wild type (GG), 38.88 and 29.64 % for the heterozygotes (TC), and 6.94 and 3.48 % for the risk allele homozygotes (TT) for the GDM non-GDM populations, respectively. Carriers of BDNF rs925946 were significantly associated with higher risk for GDM, following the dominant genetic model (OR=1.7, 95 % CI 1.21–2.39, p=0.002), the recessive genetic model (OR=2.05, 95 % CI 1.04–4.03, p=0.03), and the additive genetic model (OR=1.62, 95 % CI 1.13–2.3, p=0.008). This association persisted after adjusting for age, T1DM, T2DM, and polycystic ovary syndrome (PCOS).

Conclusions
Carrying BDNF rs925946 polymorphism predisposes to a higher risk of GDM pathogenesis. Its role and implications warrant further investigation, especially when considering preventive measures for GDM development.
Clinical applications and challenges of metagenomic next-generation sequencing in the diagnosis of pediatric infectious disease
Authors: Guo Qiang , Zhang Shihai 
Published: May 2024

Abstract
Infectious diseases seriously threaten the lives of children. Timely and accurate detection of pathogenic microorganisms and targeted medication are the keys to the diagnosing and treatment of infectious diseases in children. The next-generation metagenomic sequencing technology has attracted great attention in infectious diseases because of its characteristics such as no culture, high throughput, short detection cycle, wide coverage, and a good application prospect. In this paper, we review the studies of metagenomic next-generation sequencing in pediatric infectious diseases and analyze the challenges of its application in pediatric diseases.
Transformer-based intelligent fault diagnosis methods of mechanical equipment: A survey
Authors: Wang Rongcai , Dong Enzhi , Cheng Zhonghua , Liu Zichang , Jia Xisheng 
Published: May 2024

Abstract
Transformer is extensively employed in natural language processing, and computer vision (CV), with the self-attention structure. Due to its outstanding long-range dependency modeling and parallel computing capability, some leading researchers have recently attempted to apply Transformer to intelligent fault diagnosis tasks for mechanical equipment, and have achieved remarkable results. Physical phenomena such as changes in vibration, sound, and heat play a crucial role in the research of mechanical equipment fault diagnosis, which directly reflects the operational status and potential faults of mechanical equipment. Currently, intelligent fault diagnosis of mechanical equipment based on monitoring signals such as vibration, sound, and temperature using Transformer-based models remains a popular research topic. While some review literature has explored the related principles and application scenarios of Transformer, there is still a lack of research on its application in intelligent fault diagnosis tasks for mechanical equipment. Therefore, this work begins by examining the current research status of fault diagnosis methods for mechanical equipment. This study first provides a brief overview of the development history of Transformer, outlines its basic structure and principles, and analyzes the characteristics and advantages of its model structure. Next it focuses on three model variants of Transformer that have generated a significant impact in the field of CV. Following that, the research progress and current challenges of Transformer-based intelligent fault diagnosis methods for mechanical equipment are discussed. Finally, the future development direction of Transformer in the field of mechanical equipment fault diagnosis is proposed.
Lessons learned from bovine subclinical endometritis: a systematic review exploring its potential relevance to chronic endometritis in women
Authors: Krasniqi Kaltrina , Black Naomi , Williams Erin J , Bogado Pascottini Osvaldo , Thornton Sarah , Quenby Siobhan , Odendaal Joshua 
Published: May 2024

Chronic endometritis (CE) in humans is asymptomatic inflammation of the endometrium, associated with poor reproductive outcomes. Similarly, asymptomatic endometrial inflammation in cows, termed subclinical endometritis (SCE), is associated with adverse reproductive outcomes. While the pathophysiology and treatment options for CE in humans remain poorly defined, the well-known financial implications of SCE in dairy cows have attracted intensive research. We performed a systematic review to determine potential areas of interest in human CE research, by analysing emergent themes that arose in studies of SCE in cows. A literature search for studies of subclinical endometritis in cows published between 1990 and November 2021 was performed across Embase, Medline, Scopus and CINAHL. Studies of symptomatic or clinical endometritis were excluded. A thematic analysis across two broad themes was explored: i) diagnostic methods of SCE and ii) pathophysiology of SCE. In total, 51 bovine studies were included. Twelve studies reported on diagnostic methodology. The primary emergent theme was the use of cytology for the diagnosis of SCE. Cytological analysis has a lower sensitivity than histopathology but is less invasive and more specific than alternative techniques such as ultrasound, vaginoscopy or metabolic markers. The subthemes related to pathophysiology were identified as the type of endometritis, metabolic stress, artificial insemination, infective causes and altered cellular pathways. Despite the lack of symptoms, cellular pathways of inflammation including NF-κB, MAPK and inflammasomes were found to be activated. The key themes related to the diagnosis and pathophysiology of SCE in cows identified in this systematic review highlight potential areas for future research into human CE.

Lay summary
Long-term or chronic endometritis (CE) is a condition associated with inflammation in the womb lining. People with CE commonly experience recurrent miscarriages and subfertility. The cause of CE is poorly understood, and as such there are no specific treatments. Comparatively, a form of CE (i.e. subclinical endometritis (SCE)) has been extensively researched in dairy cows due to its financial impact. A systematic review of cow studies was carried out and key themes around cause and diagnosis of SCE in cows were identified and analysed. In total, 44 studies were included. Six main themes around the way SCE is diagnosed were found, and examining cells (i.e. cytology) was found to be more sensitive and practical than other techniques. Six themes were also found for causes of SCE, notably difficult delivery, metabolic stress and infection. This study shows potential areas for future research into human SCE and provides insight into the causes of disease within humans.
Effect of graphene on properties of acrylic emulsion intumescent fire retardant coating
Authors: Mac Van Phuc  , Dao Phi Hung  , Nguyen Anh Hiep  , Nguyen Thien Vuong  , Trinh Van Thanh  
Published: May 2024

Nowadays, intumescent paint is one of the most popular fireproof paint products and is widely used in buildings. They can be applied to steel, wood, concrete, etc. This study aimed to enhance the properties of intumescent coating by graphene addition. The effect of graphene (GR) content on fire resistance, thermal and mechanical properties of water-based intumescent coatings were studied. Intumescent coating formulations include acrylic emulsion binder (R4152), flame retardant additives (Ammonium polyphosphate (APP) - acid source, pentaerythritol (PER) - carbon source, melamine (MEL) - foaming source), fire retardant fillers (TiO2, Al(OH)3) were prepared by mixing different graphene content (0.5, 1, 1.5 and 2 wt.% GR). The investigated coating properties were examined by fire protection test, furnace test, static water immersion test, scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and mechanical properties (adhesion, pendulum hardness). The results showed that the GR could effectively enhance the fire resistance performance (from 13.6 % to 23.4 %), thermal stability (from 2.9 % to 5.2 %), water resistance (from 5.0 % to 11.9 %), and mechanical properties (from 5 % to 12 %) of the coating.
Educação ambiental nos ambientes formais e não formais: relato de experiência em Parintins-AM
Authors: Smith Itacinara Paulain , Azevedo Daiana da Costa , Souza Michel Souza de , Ferreira Thiago Xisto , Azevedo Filho João D’Anuzio Menezes de 
Published: May 2024

Este relato de experiência trata do projeto de extensão desenvolvido na cidade de Parintins, no estado do Amazonas, com o título Educação Ambiental e Sustentabilidade em espaços formais e não formais no município de Parintins – AM, financiado pela Universidade do Estado do Amazonas, através do Projeto de Apoio e Desenvolvimento da Extensão (PADEX) com o objetivo de disseminar a importância do desenvolvimento sustentável e a educação ambiental nos ambientes formais e não formais e desenvolver atividades de sensibilização ambiental. Foram realizados levantamento bibliográfico e discussão da temática com os envolvidos, foi organizada palestra de sensibilização em escolas selecionadas e em comunidades locais. Foi preparada uma oficina de aproveitamento de papel descartado e confecção de papel reciclado. O projeto está em andamento.
Raman Spectroscopy of carbonaceous material thermometry in the Carnic Alps (Austria, Italy)
Authors: Rantitsch Gerd 
Published: May 2024

Abstract
The Carnic Alps (eastern Southern Alps) provide a classical area to study polyphase very-low- to low-grade metamorphism within the Variscan belt of Europe. Temperature indicators collected during the past three decades map the general metamorphic structure of a mountain chain affected by three major tectonic events (Variscan and Alpine thrusting, Oligocene transpression). Thermometric data obtained by Raman Spectroscopy of carbonaceous material (RSCM) described in this study extend the already published database, provide a map of metamorphic isotherms, and are interpreted in the view of current tectonic concepts. The RSCM temperatures of this study describe a gradient between ca. 460 °C in the tectonically deepest segments, bordered by the Periadriatic Fault System, and temperatures of ca. 200 °C in Permian- Triassic boundary strata of the Gartnerkofel-1 core. Mapped isotherms indicate three domains with different thermal histories, characterized by Variscan imbrication of an accretionary wedge, Permo-Mesozoic burial, and Oligocene contact metamorphism.
Rola i wykorzystanie badań wysokoprzepustowych w poszukiwaniu związków chemicznych o działaniu terapeutycznym
Authors: Karczewska Natalia , Pyc Monika , Żukowski Krzysztof , Kosman Joanna , Kwiatek Dorota , Kolanowski Jacek 
Published: May 2024

With the development of medicine and the aging population, the demand
for more effective therapies is escalating. A tool that facilitates the discovery and
introduction of new therapeutic drugs is High-Throughput Screening (HTS). These tests, consisting of a wide set of various assays, allow testing hundreds of thousands of compounds in a short period of time. The aim is to accurately identify active compounds that could become potential therapeutic candidates in the pharmaceutical industry. HTS is the first step in the quest for potential drugs, therefore it is one of the crucial tests that determine whether a particular drug candidate will be discovered. In this review, different stages of high-throughput screening studies will be described, as well as methods utilized in these studies. The necessary steps in the optimization of these tests, selection of equipment, automation and key quality control parameters for reliably performed screening will also be presented.
Osteosarcoma After Total Knee Arthroplasty
Authors: Martínez-Collado Pablo , Pujol Oriol , Bustos Andrés , Plomer Martí , Carrasco María G. , Silva Tulio , Vélez Roberto , Minguell Joan 
Published: May 2024

Case:
A 79-year-old woman presented with a periprosthetic fracture 8 years after a total knee arthroplasty (TKA). Radiographs demonstrated tibial implant loosening with severe osteolysis. A high-grade osteosarcoma around the prosthesis was diagnosed, and a supracondylar femoral amputation was performed. After 2 years, no complications have occurred.

Conclusions:
A malignant tumor around a TKA is extremely rare. Surgeons should remain vigilant with patients who present with rapidly progressive or very aggressive implant loosening with osteolysis. Owing to its complexity and potentially devastating prognosis, treatment should be guided by a specialist multidisciplinary team. Complex limb salvage procedures or amputation is usually required.
Acute-on-Chronic Axillary Artery Thrombus After Reverse Total Shoulder Arthroplasty for Failed Proximal Humerus Open Reduction and Internal Fixation
Authors: Hoffman Ryan A. , Covarrubias Oscar , Green Andrew , Paxton E. Scott 
Published: May 2024

Case:
A 71-year-old woman presented with post-traumatic arthritis 11 months after open reduction and internal fixation for a left proximal humerus fracture (PHF) dislocation. After revision to reverse total shoulder arthroplasty (rTSA), the patient's left upper extremity was found to be avascular. An emergent thrombectomy was performed with restoration of arterial flow after removal of an acute-on-chronic axillary artery thrombus.

Conclusion:
Although rare, as rTSA becomes more common for management of PHF, incidence of associated vascular injuries is likely to rise. Screening methods and clinical vigilance in diagnosis are advised for patients with anterior PHF dislocations and arterial injury risk factors.