bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental Education Workshops to Mitigate the Environmental Problems in the Region of Madre de Dios – Peru
Authors: Pari Yony Raúl Chambilla , Camargo María Isabel Puma , Ramos Carlos Béjar 
Published: April 2024

Objective: Determine to what extent environmental education workshops mitigate the environmental problems of the Madre de Dios region - Peru.

Theoretical framework: The currents that stand out most in environmental education are: conservationist, naturalistic, systemic, scientific, decisive, humanistic and moral-ethical.

Methodology: Applied quantitative approach, quasi-experimental design and explanatory level, the units of analysis were two independent samples (control and experimental group), made up of students from a regular basic secondary institution in the Madre de Dios region, the The technique was observation and the instrument was the checklist.

Results and conclusion: The environmental education workshops significantly mitigate the environmental problems of the Madre de Dios region, since the p-value associated with the Mann Whitney U statistic (Sig. Asymptotic) is 0.000; This value is less than 0.05, then at the 1% significance level; The total scores are different in both groups after carrying out the environmental education workshops with the students.

Implications of the research: Environmental education in regular basic education contributes to the practice of environmental values, since it seeks through problematic situations to make the relationship between the learning contents and the reality of the context that surrounds the students. These, in turn, build their representations of reality and begin to commit more consciously to their individual and collective actions in the environment in which they live.

Originality/value: The article offers results from the application of environmental education workshops to mitigate environmental problems in the Madre de Dios region of Peru.
The Performance Measurement Construction for Developing Prosperity and Sustainability of Social Enterprises
Authors: Nurindrasari Diana , Ludigdo Unti , Purwanti Lilik , Mulawarman Aji Dedi 
Published: April 2024

Objective: This research seeks to enhance existing knowledge by proposing an approach for social enterprises to evaluate their impact across social, environmental, and economic dimensions.

Method: Drawing on insights in accounting and anthropology, we employ a synchronic-diachronic approach. Our research utilizes deep ecology to build a comprehensive framework for measuring SE performance.

Results and Conclusion: Our study advocates a multidimensional perspective rooted in the principles of deep ecology, which includes environmental and community well-being, internal processes, human and natural empowerment, and equitable distribution. By embracing this multidimensional view, SEs can work towards achieving their ultimate goals of sustainability and well-being.

Implications of The Research: Despite the proliferation of methodologies and tools to assess social impact, there is a lack of systematic analysis and comparison across these approaches. SE should adopt systematic performance measurement to inform decision-making and promote environmental and social sustainability.

Originality/Value: This research contributes to the existing literature by specifically focusing on the performance measurement of social enterprise, with comprehensive approaches uses deep ecology.
Uma análise das tendinopatias: tendinopatia de Aquiles e tendinopatia patelar
Authors: Santos João Vitor Tavares Morais dos , Rodrigues Gabriel Michelini , Ferreira Rian Magro , Siqueira Emílio Conceição de 
Published: April 2024

Objetivo: Analisar as características da tendinopatia de Aquiles (TA) e da tendinopatia patelar (TP). Revisão bibliográfica: A tendinopatia representa degeneração ou falha na cicatrização devido à sobrecarga contínua sem recuperação adequada do tendão acometido. Afeta indivíduos sedentários e ativos, sendo responsável por 30% a 50% de todas as lesões esportivas. Ambos os membros superiores e inferiores são acometidos, sendo comumente acometidos os tendões do manguito rotador, lateral do cotovelo, glúteo, patelar e tendão de Aquiles. A TA é uma lesão dolorosa por uso excessivo do tendão de Aquiles, enquanto a TP é uma lesão crônica comum do tendão caracterizada por dor relacionada à carga no tendão patelar. Considerações finais: A TP e a TA se apresentam como dor e edema dentro e ao redor do tendão, principalmente em decorrência do uso excessivo no caso de atletas ou em pacientes com sobrepeso por sobrecarga. O manejo dessas condições é feito, primariamente, de forma conservadora com o uso de exercícios excêntricos, anti inflamatórios, injeções no tendão e terapia extracorpórea por ondas de choque além de ultrassom terapêutico e laserterapia. Na falha dessas terapêuticas por 3 a 6 meses considera-se os procedimentos cirúrgicos.
Relato de caso: placenta percreta com invasão vesical
Authors: Guimarães Ana Paula Pereira , Bertoloni Camila Rita de Souza , Soares Daniela Elianete 
Published: April 2024

Objetivo: Relatar o caso de uma paciente com apenas uma cesariana anterior que apresentou diagnóstico de placenta prévia e percreta, com invasão vesical e, que apesar da gravidade do caso, apresentou boa evolução. Detalhamento do caso: Gestante, 37 anos, com histórico de uma cesariana. Encaminhada com 37 semanas e 3 dias para interrupção da gestação devido placenta prévia total e acretismo placentário. No ato operatório foi identificada intensa vascularização da parede uterina anterior com invasão placentária da bexiga, o que confirmou o diagnóstico intraoperatório de placenta percreta. Após histerotomia, o recém-nascido foi entregue em boas condições ao pediatra. Em seguida, paciente apresentou sangramento volumoso com dificuldade na hemostasia. Sem dequitação placentária, foi iniciada histerectomia subtotal. Houve lesão vesical extensa, próxima à inserção dos ureteres e realizada cateterização ureteral bilateral e cistorrafia. Paciente recebeu cuidados intensivos e, após estabilidade clínica, teve alta com sonda vesical de demora que posteriormente foi retirada. O anatomopatológico confirmou acretismo placentário. Considerações finais: É necessária programação cirúrgica rigorosa nos casos de placenta percreta para diminuição da morbimortalidade materna e neonatal.
Immunohistochemical evaluation of tumor hypoxia and angiogenesis: Pathological significance and prognostic role in head and neck squamous cell carcinomas
Authors: Soni Deepti , Mukhopadhyay Sramana , Goel Garima , Kapoor Neelkamal , Gupta Vikas , Das Saikat 
Published: April 2024

Objectives:
Tumor hypoxia and angiogenesis have been implicated in therapeutic resistance of head and neck squamous cell carcinomas (HNSCCs). Immunohistochemical evaluation of hypoxia-inducible factor-1 alpha (HIF-1 α), a hypoxia transcription factor, and vascular endothelial growth factor (VEGF), a hypoxia-responsive pro-angiogenic factor, can be exploited for prognostication and guiding treatment intensification or de-escalation decisions in HNSCC patients. The purpose of the study is to evaluate the immunohistochemical expression patterns of HIF-1 α and VEGF and the microvessel density (MVD) for angiogenesis in HNSCC and assess their pathological significance and prognostic role.

Materials and Methods:
In this cross-sectional study, immunohistochemical expression of HIF-1 α, VEGF, and MVD through Cluster of Differentiation (CD31) was evaluated in paraffin-embedded tumor resection tissue of 44 patients with HNSCC. Associations among HIF-1 α, VEGF, and MVD with clinicopathological variables were assessed.

Statistical Analysis:
For assessment of association between HIF-1α, VEGF and MVD by CD 31 immunohistochemical markers and other clinicopathological variables Pearson’s chi-square test and Fisher’s exact tests were used. Analysis of survival was done using Kaplan-Meier statistics. Also, the univariate and multivariate analysis were performed using the Cox proportional hazard regression model for the calculation of hazard ratios.

Results:
Nuclear expression of HIF-1 α showed significant association with MVD (P = 0.007) and cytoplasmic expression of HIF-1 α with histologic grade (P = 0.03). Overexpression of HIF-1 α was more frequent in T3/T4 stage. In addition to cytoplasmic staining, VEGF showed a unique nuclear expression pattern in four cases of advanced disease with nodal metastasis. Logistic regression analysis showed tumors with nuclear overexpression of HIF-1 α to have increased MVD (P = 0.05), and tumors with higher MVD to have a presence of lymphovascular invasion (P = 0.014). Multivariate analysis showed HIF-1 α nuclear overexpression to be significantly associated with decreased survival of patients (P = 0.05).

Conclusions:
Immunohistochemical overexpression of HIF-1 α and MVD quantification can serve as cost-effective tools for prognostication and treatment modification of HNSCC patients in resourcelimited settings.
Isolated hypertelorism: Late surgical correction using the box osteotomy technique
Authors: de Sousa Bruna Cavalcante , Ferreira-Pinto Pedro Henrique Costa , Ferreira Domênica Baroni Coelho de Oliveira , Bastos Eduardo Pantoja , Junior Marcio Lima Leal Arnaut , Dias Bruno Santos de Barros , Schneider Thiago , Claro Valéria , Cintra Henrique Pessoa Ladvocat , Parise Maud , Correa Eduardo Mendes , Cruz Thaina Zanon , da Silva Wellerson Novaes , Nigri Flavio 
Published: April 2024

Background:
Orbital hypertelorism is a rare congenital condition caused by craniofacial malformations. It consists of complete orbital lateralization, characterized by an increase in distance (above the 95th percentile) of the inner canthal (ICD), outer canthal, and interpupillary distances. It can be approached surgically, and the main techniques are box osteotomy and facial bipartition. The surgical procedure is usually performed before the age of 8. We describe here two patients who underwent late surgical correction using the box osteotomy technique.

Case Description:
Patient 1: A 13-year-old female presenting isolated hypertelorism with 5 cm ICD and left eye amblyopia. Patient 2: A 15-year-old female with orbital hypertelorism, 4.6 cm ICD, and nasal deformity. Both patients underwent orbital translocation surgery and had no neurological disorders.

Conclusion:
The article reports two cases of isolated hypertelorism treated late with the box osteotomy technique. Both surgeries were successful, with no postoperative complications. It appears that it is possible to obtain good surgical results even in patients who have not been able to undergo surgery previously.
Multiple Abdominal abscesses following ventriculoperitoneal shunt placement in an immunosuppressed patient: An illustrative case
Authors: Gulino Vincenzo , Costanzo Roberta , Pedalino Francesca , Salvaggio Giuseppe , Gagliardo Cesare , Iacopino Domenico Gerardo , Maugeri Rosario 
Published: April 2024

Background:
Ventriculoperitoneal (VP) shunt placement is one of the most performed procedures in neurosurgery to treat various types of hydrocephalus (HC). Immediate or late postoperative complications may quite commonly occur, especially in immunosuppressed patients, who are predisposed to develop rare and difficult-to-treat conditions.

Case Description:
Herein, we report the case of a 41-year-old female patient with a prior history of acute myeloid leukemia, followed by a tetra-ventricular acute HC due to a spontaneous non-aneurysmal subarachnoid hemorrhage. After an urgent external ventricular drainage placement, she underwent careful testing of “shunt dependency,” which ended with a VP shunt placement. After 2 months, she presented at the emergency department with worsening abdominal pain and fever. She underwent a computed tomography scan with contrast administration, which has shown abscesses in the abdominal cavity. An urgent surgical revision of the VP shunt and antibiotics administration followed this. After inflammatory markers normalization, due to the high risk of post-infective peritoneal adherence and consequent impairment of cerebrospinal fluid absorption, a ventriculoatrial shunt was considered the most appropriate solution.

Conclusion:
Abdominal abscesses are a rare but subtle complication after VP shunt placement. Their management depends on etiology, patient clinical characteristics, and manifestations. Prompt interventions have been shown to improve clinical outcomes and optimize quality of life in such delicate patients.
Multimodal management of giant solid hemangioblastomas in two patients with preoperative embolization
Authors: Vargas-Urbina John , Crisanto-Silva John Alex , Vásquez-Perez Carlos , Davila-Adrianzén Aarón , Alcas-Seminario Daniel , Lines-Aguilar William , Mamani-Choquepata Rocio , Panta-Rojas Giuseppe 
Published: April 2024

Background:
Hemangioblastomas are benign vascular neoplasms, World Health Organization grade I, with the most frequent location in the cerebellum. Complete microsurgical resection can be a challenge due to excessive bleeding, which is why preoperative embolization takes importance.

Case Description:
Two clinical cases are presented, a 25-year-old woman and a 75-year-old man, who presented with intracranial hypertension symptoms due to obstructive hydrocephalus; a ventriculoperitoneal shunt was placed in both cases; in addition, they presented with cerebellar signs. Both underwent embolization with ethylene vinyl alcohol copolymer, with blood flow reduction. After that, they underwent microsurgical resection within the 1st-week post embolization, obtaining, in both cases, gross total resection without hemodynamic complications, with clinical improvement and good surgical outcome. It is worth mentioning that surgical management is the gold standard that allows a suitable surgical approach, like in our patients, for which a lateral suboccipital craniotomy was performed.

Conclusion:
Solid hemangioblastomas are less frequent than their cystic counterparts. The treatment is the surgical resection, which is a challenge and always has to be considered as an arteriovenous malformation in the surgical planning, including preoperative embolization to reduce perioperative morbidity and mortality and get good outcomes.
ОЦЕНКА ЗАГРЯЗНЕННОСТИ ВОДНЫХ ОБЪЕКТОВ ХРЕБТА ИРАНДЕК РЕСПУБЛИКИ БАШКОРТОСТАН
Authors: Бускунова Г.Г. , Хисаметдинова А.Ю. , Янтурин С.И. 
Published: April 2024

В данной статье рассматривается проблема содержания тяжелых металлов в водах малых рек Республики Башкортостан. Исследованы поверхностные воды некоторых рек восточного и западного склонов хребта Ирандек Башкирского Зауралья по содержанию в них тяжелых металлов (медь, цинк, железо, кадмий, свинец). Установлено превышение значений предельно допустимых концентраций рыбохозяйственного назначения по меди (от 6ПДК до 938ПДК) во всех точках отбора. Реки западного склона (р. Шугур, р. Улак-1, р. Улак-2, р. Тукмак, р. Акменды) хребта Ирандек, по сравнению с реками восточного склона (р. Туялас, р. Карагайлы, р. Ургаза, р. Шурале) характеризовались наибольшими концентрациями кадмия, свинца. Оценка качества вод по индексу загрязнения показала, что воды р. Туялас, р. Карагайлы относились к категории умеренно загрязненная, р. Ургаза, р. Шурале – загрязненная, р. Улак-1 – грязная, р. Шугур, р. Улак-2 – очень грязная, р. Тукмак, р. Акменды – чрезвычайно грязная.
DETERMINATION OF THE RADIATION SAFETY OF SOLID WASTES GENERATED IN THE PURIFICATION PROCESS WITH HYDROGEN OF PETROLEUM OILS
Authors: Гусейнли А.М. 
Published: April 2024

В статье проведены анализы по определению радиационной безопасности пробы, отобранной из твердых отходов, полученных в процессе рафинации нефтяных масел водородом. Отходы катализаторов AlCoMo и AlCoNi, использованных в процессе, принимали за твердые отходы. Анализом содержания радионуклидных элементов в образцах катализатора определены характеристики радиационной безопасности образцов. Приведены спектры образца твердых отходов, классифицировано и сведено в таблицу содержание радионуклидов.
In the article, analyzes were made on determining the radiation safety of the sample taken from the solid waste obtained during the process of refining petroleum oils with hydrogen. Waste of AlCoMo and AlCoNi catalysts used during the process were taken as solid waste. The analysis of the radionuclide element composition in the catalyst samples and the radiation safety characteristics of the samples were determined. The spectra of the solid waste sample are shown, the radionuclide content is classified and tabulated.
Defragmenting Student Construction Holes in Solving System of Absolute Value Equations
Authors: Putri Rizky Widya , Indrawatiningsih Nonik 
Published: April 2024

Constructing concepts is one of the processes in learning mathematics. Making mistakes in constructing concepts is often experienced by students in solving mathematical problems, errors in constructing concepts that can be experienced are construction pits. Construction holes can occur if the schemes that are formed in the thinking structure of students have not been fully constructed or not, students cannot construct concepts properly and completely. This research is a descriptive study with a qualitative approach that aims to defragment the students' construction holes in solving systems of equations in the linear absolute value of one variable. The subject of this study was a class X high school student who fit the indicator for defragmenting the construction pit that is answering correctly but there was a construction process that was not appropriate and students answering correctly but the concept was not fully constructed. Data collection was carried out using test and interview instruments and analyzed ie reducing data, presenting data and drawing conclusions. The validity of the data is done by passing triangulation by comparing test results with interview results. From the results of this study it was found that students 'construction holes were located when simplifying absolute values ​​and determining the values ​​of and were therefore given defragmenting by providing conflict cognitive to sensitize students' mistakes in simplifying absolute values ​​and then new schemes emerged through scaffolding so that schemes were not constructed in a constructional manner. complete when determining the values ​​of and can be completely constructed.
Model Pembelajaran SIMAS ERIC : Dampak Terhadap Komunikasi Matematis dan Self Efficacy Siswa
Authors: Az-zahra Nadia , Netriwati Netriwati , Andriani Siska , Nendra Fadly 
Published: April 2024

SIMAS ERIC yaitu Skimming, Mind Mapping, Questioning, Eksploring, Writing, dan Communicating merupakan model pembelajaran inovatif dengan 6 tahapan didalamnya. Model ini mampu menggiring siswa menjadi aktif dan mandiri dalam proses pembelajaran. Penelitian ini menggunakan metode kuantitatif dengan jenis penelitian quasi eksperimen design. Populasi pada penelitian ini dilakukan di kelas 8 SMPN 6 Metro. Penelitian ini menggunakan dua kelas yaitu penelitian kelas kontrol dan kelas eksperimen dengan teknik random sampling. Teknik pengumpulan data pada penelitian ini menggunakan tes, angket, wawancara, dan dokumentasi. Instrumen pada penelitian ini menggunakan tes dan angket. Teknik analisis data pada penelitian ini menggunakan uji normalitas, homogenitas, dan hipotesis. Uji hipotesis menggunakan uji MANOVA (Multivariate Analisis of Variance). Hasil penelitian menunjukkan bahwa diperoleh dampak positif dari model pembelajaran SIMAS ERIC terhadap komunikasi matematis dan self efficacy.
İQTİSADİ İNKİŞAFDA GENDER AMİLİ: FEMİNİST İQTİSADİ YANAŞMALAR
Authors: J.J. Hajiyev  , A.A. Aghazade  , S.A. Mahmudova  
Published: April 2024

Qadın və kişinin cəmiyyətdəki rolu müxtəlif sahələrdə olduğu kimi iqtisadiyyata və xüsusən də iqtisadi inkişafa böyük təsir edir.Ancaq ənənəvi iqtisadi yanaşma perspektivlərinin kişiləri ön plana çəkdiyi və qadınların mövcud vəziyyətini izah etməkdə yetərli olmadığı müşahidə edilir. Ümumiyyətlə “Qadın və İqtisadiyyat” mövzusunda müxtəlif zamanlarda müəyyən işlər aparılmış olsa da, ”Feminist iqtisadiyyat”ının və ya “Gender iqtisadiyyat”ının tam olaraq ortaya çıxışı 1980-ci illərə təsadüf edir. Feminist iqtisadiyyat, iqtisadiyyatda qadının yerini sorğulamaq niyyətində deyil,ənənəvi iqtisadiyyatda qadın baxışınıda içində saxlayacaq yeni bir yanaşma yaratmaq məqsədindədir. Ancaq illər boyu qadınların iqtisadi və sosial həyatda məhdudlaşdırılması, yetərincə söz haqqı verilməməsi səbəbi ilə feminist iqtisad daha çox qadınların məruz qaldığı bu rəftarın aradan qaldırılmasına yönəlmişdir. Bu baxımdan məqalədə Azərbaycanda qadınların iqtisadiyyatda rolu araşdırılmış və bunun iqtisadiyyata təsiri qiymətləndirilmişdir.
XANKƏNDİ ŞƏHƏRİNDƏ UCALAN ŞANLI BAYRAQ DOSTA GÜVƏN, DÜŞMƏNDƏ QORXU YARADIR
Authors: S.A. Bagirov  , E.S. Jabbarov  
Published: April 2024

Xankəndi şəhərində dalğalanmaqda olan şanlı bayraq, yerli əhali arasında dosta güvən və milli birliyi simgələyir. Bu bayraq, müstəqil dövlətin mövcudluğunu və müstəqilliyini qoruyan simvolik bir ifadədir. Onun yüksəkəldiyi hər an, milli gururun artmasına və dostlara olan etimadın güclənməsinə səbəb olur. Əksər təbirlərlə, şanlı bayraqlar milli mənfəət və vətəndaşlıq hisslərinin bir araya gəldiyi simvolik nümayişlərdir. Bu bayrağın dalğalanması, yerli əhaliyə güvən və güclü bir milli birlik hissi verməkdə, müstəqil dövlətin simvolu olaraq özünü təqdim etməkdə əhəmiyyətli rolu oynayır.
La enfermedad crónica bajo la urticaria: más allá del prurito
Authors: Moreno Lozano Lucía , De Aramburu Mera , Bermúdez-Hormigo Carmen 
Published: April 2024

Introduction:
Short-lasting erythematous-papular skin rashes suggest a clinical diagnosis of urticaria. However, it may be another type of dermatitis whose diagnosis may require complementary examinations.

Case report: 53-year-old woman diagnosed in 2016 with diffuse large B-cell lymphoma in complete remission. Since 2010 she presented daily episodes of erythematous-papular lesions lasting 24-36 hours. She was treated with antihistamines, oral corticosteroids and Omalizumab without control.

A study was carried out consisting of:
Blood tests: haemogram, serum immunoglobulins, thyroid hormones, complement, cryoglobulins, proteinogram, autoimmunity markers. Of note: positive ANA 1/320 mitotic nuclear pattern.
Skin biopsy (x2) compatible with dermatitis herpetiformis.
Celiac disease antibodies and HLA DQA1 and DQB1 locus. HLA-DQ2 positive DQ2.5 in heterozygosis.
Discussion: Dermatitis herpetiformis was diagnosed and a gluten-free diet and dapsone were indicated with good control, highlighting the importance of differential diagnosis of papular exanthema.