bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasmonic Cross‐Reactive Sensing Noses and Tongues
Authors: Calderon Irene , Becerril‐Castro I. Brian , Zorlu Tolga , Özdemir Burak , García‐Rico Eduardo , Baulin Vladimir A. , Alvarez‐Puebla Ramon A. 
Published: June 2024

AbstractThe advancements in the capabilities of artificial sensory technologies, such as electronic/optical noses and tongues, have significantly enhanced their ability to identify complex mixtures of analytes. These improvements are rooted in the evolving manufacturing processes of cross‐reactive sensor arrays (CRSAs) and the development of innovative computational methods. The potential applications in early diagnosis, food quality control, environmental monitoring, and more, position CRSAs as an exciting area of research for scientists from diverse backgrounds. Among these, plasmonic CRSAs are particularly noteworthy because they offer enhanced capabilities for remote, fast, and even real‐time monitoring, in addition to better portability of instrumentation. Specifically, the synergy between the localized surface plasmon resonance (LSPR) of metallic nanoparticles (NPs) and CRSAs introduces advanced techniques such as LSPR, metal‐enhanced fluorescence (MEF), surface‐enhanced infrared absorption (SEIRA), surface‐enhanced Raman scattering (SERS), and surface‐enhanced resonance Raman scattering (SERRS) spectroscopies. This review delves into the importance and versatility of optical‐CRSAs, especially those based on plasmonic materials, discussing recent applications and potential new research directions.
Application and Challenge of Metal/Covalent Organic Frameworks in Ammonia Sorption and Separation
Authors: Fu Yu , Zhang Wenxiang , Ma Heping 
Published: June 2024

AbstractAs both a critical chemical feedstock and an environmental pollutant, the production and utilization of ammonia (NH3) are accompanied by the progress of social civilization. In recent years, research on metal/covalent organic framework materials as NH3 adsorbents has attracted increasing attention due to their high porosity, versatile architecture and tunable functionality. This review was organized to highlight the recent advancement of MOF/COF materials for NH3 sorption, which successively presented the key properties of solid adsorbents and summarized the strategies along with their mechanisms for enhancing NH3 adsorption. In addition, perspectives and outlook regarding the future development of MOF/COF‐based NH3 adsorbents were outlined to meet the requirements of practical applications under various condition.
Photocatalytic Functionalization of Alkenes Enabled by Polyfluoroaryl Migration
Authors: Savchenko Artem G. , Zubkov Mikhail O. , Hu Jinbo , Dilman Alexander D. 
Published: June 2024

AbstractVisible light‐mediated photocatalytic approach for the radical functionalization of alkenes bearing the fluorinated aryl sulfide fragment is described. The process occurs in the presence of organic photocatalyst using sulfinates as sources of radicals. The key step of the reaction is the intramolecular 1,4‐migration of the polyfluoroaryl group. In the reaction, three new bonds are formed (two C−C and one C−S bond). The decisive role of fluorine atoms in the reaction efficiency was confirmed by DFT calculations.
The link of ESG performance and board gender diversity in European firms
Authors: Odriozola María D. , Blanco‐González Alicia , Baraibar‐Diez Elisa 
Published: June 2024

AbstractThis study analyses the relationship between board gender diversity and the ESG scores for Spanish, French, German, and English listed companies. Previous academic literature shows controversial results regarding the benefits of female participation in boards of directors, however many studies have only used an aggregated indicator to measure performance or they do not have compared the results among countries. The empirical section of this research uses a sample formed by 205 companies from France, Germany, Spain, and the United Kingdom for a period of 19 years (from 2002 to 2020). The results obtained through a panel data estimation confirm a positive and significant relationship between board gender diversity (BGD) and the social and the corporate governance score in all cases. However, the relationship between BGD and the environmental score is only confirmed in the case of Spain, France, and Germany. Therefore, even though in these countries, the actions to promote gender equality have been different and at different times, the results are mostly homogeneous.
Lithium‐Ion Transport Properties in DMSO and TEGDME: Exploring the Influence of Solvation through Molecular Dynamics and Experiments
Authors: Piacentini Vanessa , Simari Cataldo , Gentile Antonio , Marchionna Stefano , Nicotera Isabella , Brutti Sergio , Bodo Enrico 
Published: June 2024

AbstractThis study explores the properties of aprotic electrolytes via the application of experimental methods, including nuclear magnetic resonance spectroscopy and electrochemical techniques, along with molecular dynamic modeling. The aim is to provide a quantitative description of the physico‐chemical properties of two well‐established electrolytes (case studies), each exhibiting significantly distinct dielectric properties: a LiTFSI (Lithium bis(trifluoromethanesulfonyl)imide) solution in dimethyl sulfoxide (DMSO, dielectric constant
=46.68) and a LiTFSI solution in tetraethylene glycol dimethyl ether (TEGDME,
=7.71). We obtained a comprehensive insight into the properties of the electrolytes at both the macroscopic‐collective and molecular levels with particular emphasis on the interactions between the Li ions and solvent molecules. We discovered remarkable disparities in the structural arrangements, solvation behaviors, and bulk‐related properties of these electrolyte systems, particularly in response to temperature changes.
Generalized state‐space averaging modeling to fourth‐order power converters operating in DCM
Authors: Dionizio Anderson Aparecido , Sampaio Leonardo Poltronieri , da Silva Sergio Augusto Oliveira 
Published: June 2024

AbstractThis paper presents a novel methodology for correcting the state‐space averaging (SSA) modeling for DC‐DC power converters represented for fourth‐order systems operating in discontinuous conduction mode (DCM). SSA modeling has been widely employed for converters operating in continuous conduction mode (CCM), obtaining a good similarity between the switched converter and the mathematical model. In contrast, when the converters work in DCM, significant deviations between the average and RMS values imply errors in the SSA model. Hence, the proposed generalized SSA modeling methodology provides an accurate model to aid the controllers and system design. Consequently, the proposed technique can be applied to distinct fourth‐order power converters such as Zeta, Ćuk, and SEPIC in several applications. Additionally, SSA corrections can be associated with different techniques for obtaining the small‐signals representation. Simulation and experimental results and mathematical analyses that prove the feasibility and functionality of the proposal are addressed.
Low‐power multibit delta–sigma modulator based on passive and unattenuated summation scheme
Authors: Wei Rongshan , Huang Lijie , Huang Gongxing , Wei Cong 
Published: June 2024

AbstractA low‐power multibit delta–sigma modulator (DSM) based on a passive and unattenuated summation scheme is proposed. The summation circuit achieves multiplication of the voltage signal carried on the summation capacitor through a bidirectional sampling technique, thereby compensating for the inherent attenuation caused by passive summation, which eliminates the need for an active operational transconductance amplifier (OTA) to achieve perfect summation. Here, a second‐order DSM based on a 4‐bit first‐order passive noise‐shaping (NS) SAR quantizer is employed to satisfy the SNDR requirements exceeding 100 dB, which validates the reliability of the summation scheme. In addition, a cascoded floating inverter amplifier (FIA) is used as the core OTA to further improve system energy efficiency. Simulation results demonstrate that at a supply voltage of 1.2 V and a bandwidth of 20 kHz, the SNDR reaches 102.62 dB, power consumption is only 148.32 μW, and the Schreier figure‐of‐merit (FoM) of the SNDR is 183.92 dB. The results demonstrate that the proposed DSM has considerable potential for widespread application in the audio domain.
Heart failure hospitalization following surgical or transcatheter aortic valve implantation in low‐risk aortic stenosis
Authors: Lopez‐Martinez Helena , Vilalta Victoria , Farjat‐Pasos Julio , Ferrer‐Sistach Elena , Mohammadi Siamak , Escabia Claudia , Kalavrouziotis Dimitri , Resta Helena , Borrellas Andrea , Dumont Eric , Carrillo Xavier , Paradis Jean‐Michel , Fernández‐Nofrerías Eduard , Delgado Victoria , Rodés‐Cabau Josep , Bayes‐Genis Antoni 
Published: June 2024

AbstractAimsIn low‐risk patients with severe aortic stenosis (AS), sutureless surgical aortic valve replacement (SU‐SAVR) may be an alternative to transcatheter aortic valve implantation (TAVI). The risk of heart failure hospitalization (HFH) after aortic valve replacement (AVR) in this population is incompletely characterized. This study aims to investigate the incidence, predictors, and outcomes of HFH in patients undergoing SU‐SAVR versus TAVI.Methods and resultsPatients referred for AVR between 2013 and 2020 at two centres were consecutively included. The decision for SU‐SAVR or TAVI was determined by a multidisciplinary Heart Team. Cox regression and competing risk analysis were conducted to assess adverse events. Of 594 patients (mean age 77.5 ± 6.4, 59.8% male), 424 underwent SU‐SAVR, while 170 underwent TAVI. Following a mean follow‐up of 34.1 ± 23.1 months, HFH occurred in 112 (27.8%) SU‐SAVR patients and in 8 (4.8%) TAVI patients (P < 0.001). The SU‐SAVR cohort exhibited higher all‐cause mortality (138 [32.5%] patients compared with 30 [17.6%] in the TAVI cohort [P < 0.001]). These differences remained significant after sensitivity analyses with 1:1 propensity score matching for baseline variables. SU‐SAVR with HFH was associated with increased all‐cause mortality (61.6% vs. 23.1%, P < 0.001). Independent associates of HFH in SU‐SAVR patients included diabetes, atrial fibrillation, chronic obstructive pulmonary disease, lower glomerular filtration rate and lower left ventricular ejection fraction. SU‐SAVR patients with HFH had a 12‐month LVEF of 59.4 ± 12.7.ConclusionsIn low‐risk AS, SU‐SAVR is associated with a higher risk of HFH and all‐cause mortality compared to TAVI. In patients with severe AS candidate to SU‐SAVR or TAVI, TAVI may be the preferred intervention.
The experiences of a therapeutic relationship between dietitians and patients in UK eating disorder treatment: A qualitative study
Authors: Robertson Nicole , Davies Luke 
Published: June 2024

AbstractObjectiveDietitians have a central role in eating disorder (ED) treatment, however few studies exist investigating therapeutic aspects of dietetic care and factors influencing the dietitian‐patient relationship. To address the gap, this study aimed to use a qualitative description approach to explore the experiences of delivering and receiving dietetic care in ED treatment in the UK.MethodSemi‐structured interviews were conducted with 6 specialist ED dietitians and focus groups with 11 recovered ED patients. Interviews were transcribed and inductive thematic analysis was performed to identify key themes describing the data.ResultsSix key themes were generated: (1) Building trust, (2) Appropriate timing, (3) Adapting, (4) Dietitians as experts, (5) Boundaries, and (6) Difficult relationships. Participants highlighted the importance of building trust and considering nutritional risk and readiness in treatment approach. Patients expressed a desire for dietitians to have experience in EDs, facilitating understanding of their illness. However, dietitians identified the nature of EDs making their role challenging at times.DiscussionThis study described various factors affecting dietetic care in EDs and provided a valuable insight into patients' perceptions of treatment. The findings support advancements in ED dietitians' knowledge and understanding, helping to enhance quality of care.
How omics is revealing new roles for glia in addiction
Authors: Bergkamp David J. , Neumaier John F. 
Published: June 2024

AbstractExperiments to study the biology of addiction have historically focused on the mechanisms through which drugs of abuse drive changes in the functioning of neurons and neural circuits. Glia have often been ignored in these studies, however, and this has left many questions in the field unanswered, particularly, surrounding how glia contribute to changes in synaptic plasticity, regulation of neuroinflammation, and functioning of neural ensembles given massive changes in signaling across the CNS. Omics methods (transcriptomics, translatomics, epigenomics, proteomics, metabolomics, and others) have expanded researchers' abilities to generate hypotheses and carry out mechanistic studies of glial cells during acquisition of drug taking, intoxication, withdrawal, and relapse to drug seeking. Here, we present a survey of how omics technological advances are revising our understanding of astrocytes, microglia, oligodendrocytes, and ependymal cells in addiction biology.
Psychosocial and clinical factors associated with depression among diabetic patients in Amhara region comprehensive specialized hospitals, Ethiopia, 2022; a multicenter prevalence study
Authors: Belew Makda Abate , Getu Rediet Akele , Getahun Sewunnet Azezew , Dessie Anteneh Mengist , Abeje Eleni Dagnaw , Engda Abayneh Shewangzaw , Teshome Abyot Terefe , Fita Muluken Yigezu , Alemayehu Meron Asmamaw , Workie Sewnet G. 
Published: June 2024

AbstractBackgroundDepression commonly coexists with diabetes leads to complications and worsens the outcome. Even though the problem affects low‐ and middle‐income countries including Ethiopia, only a few studies have been done to show the magnitude of the problem and factors associated with it. So, the study was conducted to fill those gapsObjectiveThe main objective of this study was to assess psychosocial and clinical factors associated with depression among diabetic patients in Amhara region comprehensive specialized hospitals, Ethiopia, 2022.MethodsA hospital‐based cross‐sectional study was conducted in randomly selected hospitals of Amhara region from January 7 to February 10, 2022. A total of 426 diabetic patients who were on outpatient follow‐up were selected using a multistage sampling technique. A p‐value of ≤0.25 in the bivariable analysis was used to select variables for the multivariable analysis. A p‐value < 0.05 within a 95% confidence interval was considered to be significantly associated factors.ResultOut of 426 interviewed diabetes patients 203 (47.7%) had depression. Moderate physical activity (AOR = 0.50, 95% CI (0.29, 0.86)). low medication adherence (AOR = 2.10, 95% CI (1.22, 3.62)), medium medication adherence (AOR = 1.78, 95% CI (1.04, 3.06)), and high social support (AOR = 0.54, 95% CI (0.33, 0.91)) were significantly associated with depression among diabetic patients.ConclusionThe overall prevalence of depression among diabetic patients was higher than in other developing countries. Hence, special attention to preventing depression and maintaining mental illness among patients with chronic illnesses, especially diabetes should be given.
Introducing PneumNet—A Groundbreaking Dual Version Deep Learning Model for Pneumonia Disease Detection
Authors: Aurangzeb Khursheed , Jamil Sonain , Alhussein Musaed 
Published: June 2024

ABSTRACTThe Internet of Medical Things (IoMT) has revolutionized healthcare, particularly in ambient assisted living (AAL). Deep learning has emerged as a powerful tool for identifying disorders and making health‐related decisions. Pneumonia, a dangerous and contagious disease, has a significant global impact. Prompt and accurate diagnosis is crucial, but traditional methods are time‐consuming and require specialized expertise. This research introduces PneumNet, a novel deep‐learning model. PneumNet consists of two versions: PneumNet v1.0 and PneumNet v2.0. The comparative analysis demonstrates PneumNet's exceptional performance. The top model achieves 99.84% accuracy, 99.87% F1‐score, 99.74% sensitivity, 100% specificity, 100% positive predictive value (PPV), and 99.58% negative predictive value (NPV). PneumNet outperforms other methods, accurately diagnosing pneumonia and improving treatment outcomes. By leveraging deep convolutional neural networks (D‐CNNs), PneumNet provides an efficient and accurate solution for pneumonia detection. These findings highlight the significance of D‐CNNs, particularly the proposed PneumNet model, in enhancing pneumonia detection accuracy and reducing mortality rates. IoMT and deep learning pave the way for transformative advancements in healthcare.
Optical‐resolution photoacoustic microelastography system for elasticity mapping: Phantom study and practical application
Authors: Wan Min , Zhang Yameng , Li Jiani , Qian Zhiyu , Gao Fan , Yang Yamin , Li Weitao 
Published: June 2024

AbstractElastography is a noninvasive technique for characterizing the mechanical properties of biological tissues. Conventional methods have limitations in resolution and sensitivity, hindering disease detection in clinical diagnostics. To address these issues, this study developed an optical‐resolution photoacoustic microelastography (OR‐PAME) system. Using an agar tissue phantom with varying agar concentrations and contrast agents, PAME evaluated elasticity distribution under compression in both lateral and axial dimensions. It indirectly measured elastic properties by correlating photoacoustic responses, temporal lags, and induced displacement. We also applied the system to the study of the distribution of elastic characteristics of the liver tissue after ablation, which confirmed the potential of OR‐PAME in the study of elastic characteristics. Quantitative analysis showed greater lateral displacement in regions with reduced agar concentrations, indicating decreased stiffness. PAME also detected vertical displacement along the axial plane, validating its efficacy in elastographic imaging. By improving resolution and penetration, PAME provides superior visualization of elasticity distribution. Its methodology correlates microstructural alterations with tissue biomechanics, holding potential implications in medical diagnostics.
Identification of a Novel Deletion Variant (c.2999_3005delTGTGTGT/p.Asn1000SerfsTer4) in NPHP4 Associated With Nephronophthisis‐4
Authors: Miri Karam Zahra , Gohari Atieh Karimi , Khabaz Mohammad Javad Rezazadeh , Yari Abolfazl , Meybodi Seyed Mahdi Emami , Attari Rezvan , Torabi Maryam , Vafaeie Farzane , Moraddahande Fateme Moradi , Amiri Sara , Saeidi Kolsoum 
Published: June 2024

ABSTRACTBackgroundNephronophthisis‐4 (NPHP4) is an inherited renal ciliopathy described by renal fibrosis and progressive impairment of kidney function. This study aimed to investigate the genetic basis and clinical manifestations of NPHP4 in two Iranian siblings.MethodsThe proband was a 27‐year‐old male with features of end‐stage renal disease, including anemia, uremia, polyuria, and polydipsia. It is worth mentioning that he has a 22‐year‐old sister with a similar presentation. Clinical diagnosis procedures, such as renal biopsy, brain imaging, blood and urine tests, cardiac evaluation, ophthalmic inspection, and auditory function assessment, were carried out to evaluate organ involvement and potential comorbidities. Whole‐exome sequencing (WES) and segregation analysis were performed to identify and confirm genetic variants associated with the condition. Computational variant analysis was conducted to evaluate the pathogenicity of the candidate variant. Furthermore, the SWISS‐MODEL server was utilized for protein modeling.ResultsThe brain, cardiac, ocular, and auditory functions were normal. Renal biopsy of the proband showed chronic interstitial inflammation and fibrosis. We found a novel homozygous 7‐base pair deletion (c.2999_3005delTGTGTGT/ p.Asn1000SerfsTer4) in exon 21 of NPHP4 by WES. Segregation analysis confirmed homozygosity for the NPHP4 variant in affected individuals and heterozygous carrier status in parents, supporting autosomal recessive inheritance. 3D protein modeling indicated significant structural changes due to the variant.ConclusionThis study expands the genetic causes and phenotypic spectrum of nephronophthisis‐4 and reveals the importance of genetic analysis in diagnosing and managing rare inherited kidney disorders, particularly those involving consanguinity.
Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men—A randomized clinical trial
Authors: Midttun Mette , Overgaard Karsten , Zerahn Bo , Pedersen Maria , Rashid Anahita , Østergren Peter Busch , Paulin Tine Kolenda , Pødenphanth Thea Winther , Karlsson Linda Katharina , Rosendahl Eva , Ragle Anne‐Mette , Vinther Anders , Rasmussen Rune Skovgaard 
Published: June 2024

AbstractBackgroundDue to increasing older populations worldwide, injuries, disabilities and deaths caused by falls among the elderly represent a growing human and societal problem. We aimed to improve health among men of at least 70 years of age with low‐normal to low testosterone and mobility problems by using testosterone undecanoate (TU) injections, progressive strength training, and oral supplements of vitamin D, calcium and protein.MethodsThis was a single‐centre, randomized, placebo‐controlled, double‐blind trial with 148 older men with a median age of 77 (73–81) years, testosterone levels at median 8 (5–9) nmol/L (full range from 1.1 to 12.9 nmol/L) and mobility problems, recruited at University Hospital of Copenhagen, Herlev Hospital, Denmark. Participants were randomized into four arms for 20 weeks: (1) TU therapy (n = 37); (2) progressive resistance training with supplements of calcium, vitamin D and protein (n = 36); (3) both interventions combined (n = 36); or (4) no intervention (n = 39). The main outcome measure was the 30‐s chair stand test, due to test performance correlating with the risk of serious fall injuries and lower extremity muscle strength. Outcome measurements were performed at baseline and after 20 weeks.ResultsAfter the intervention, the combination group receiving progressive resistance training, TU and supplements achieved a median score of 13 (11–15) compared to the control group at 10 (0–14) in the 30‐s chair stand test (P = 0.003). This median improvement of 3.0 was clinically important. Compared to the control group, participants in the combination group also increased quality of life (P < 0.05) and reduced both tiredness (P < 0.05) and leg fat (P < 0.05) and had higher variability in the RR interval (P < 0.01). The group receiving TU reduced gynoid and leg fat compared to the control group (both P < 0.05). Blood tests improved for several variables, especially in the combination group. There was no statistically significant increase in adverse effects from either the supplements or training.ConclusionsIn men ≥70 years old with low‐normal to low testosterone and mobility problems, supplements of testosterone, calcium, vitamin D and protein combined with progressive resistance training improved 30‐s chair stand test performance, muscle strength and quality of life. Both tiredness and leg fat were reduced, and RR interval variability was increased. Significant adverse effects were not observed.