bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma nitrite/nitrate concentrations in patients with schizophrenia
Authors: Djordjević Vladimir V. , Stojanović Ivana , Stanković-Ferlež Dragana , Ristić Tatjana , Lazarević Dušan , Ćosić Vladan , Djordjević Vidosava B. 
Published: January 2010

Abstract

Background: Nitric oxide (NO) is known to be a signaling molecule with many physiogical functions including apoptotic process regulation. Since apoptosis may contribute to the pathophysiology of schizophrenia, this study was undertaken to determine the plasma concentrations of NO in schizophrenics.

Methods: Nitrite/nitrate (NO2
–/NO3
–) concentrations were measured in plasma from 40 patients with schizophrenia, and 36 age- and gender-matched healthy persons using a colorimetric test.

Results: Plasma NO2
–/NO3
– concentrations were significantly higher in patients with schizophrenia (102.8±34.7 μmol/L, p<0.0001) than in controls (69.2±13.2 μmol/L). Also, mean NO2
–/NO3
– values in female patients and controls were significantly higher (118.2±44.7 μmol/L, p<0.001; 74.8±16.1 μmol/L, p<0.05, respectively) compared to males (94.7±25.3 μmol/L, 67.6±10.8 μmol/L). Significant correlation was seen between plasma NO2
–/NO3
– concentrations and heredity, number of episodes and peripheral blood mononuclear cell (PBMC) caspase-3 activity, which was significantly higher in patients than in controls (p<0.05). There was no significant difference in NO2
–/NO3
– concentrations between patients with different Positive and Negative Syndrome Scale (PANSS) scores or between patients treated with haloperidol (97.2±31.2 μmol/L) and those treated with other atypical antipsychotic drugs (109.8±33.7 μmol/L). Both parameters showed no significant differences between smokers and non-smokers.

Conclusions: This study showed that plasma NO2
–/NO3
– concentrations were significantly increased in patients with schizophrenia, being significantly higher in female than male patients, and showing a significant correlation with heredity, number of episodes and PBMC caspase-3 activity. These results suggest that NO could be considered an inducer or regulator of apoptosis in patients with schizophrenia.
Clin Chem Lab Med 2010;48:89–94.
Activation of a Poised RNAPII-Dependent Promoter Requires Both SAGA and Mediator
Authors: Lee Sarah K , Fletcher Aaron G L , Zhang Lei , Chen Xu , Fischbeck Julie A , Stargell Laurie A 
Published: January 2010

AbstractA growing number of promoters have key components of the transcription machinery, such as TATA-binding protein (TBP) and RNA polymerase II (RNAPII), present at the promoter prior to activation of transcription. Thus, while transcriptional output undergoes a dramatic increase between uninduced and induced conditions, occupancy of a large portion of the transcription machinery does not. As such, activation of these poised promoters depends on rate-limiting steps after recruitment of TBP and RNAPII for regulated expression. Little is known about the transcription components required in these latter steps of transcription in vivo. To identify components with critical roles in transcription after recruitment of TBP in Saccharomyces cerevisiae, we screened for loss of gene expression activity from promoter-tethered TBP in &gt;100 mutant strains deleted for a transcription-related gene. The assay revealed a dramatic enrichment for strains containing deletions in genes encoding subunits of the Spt-Ada-Gcn5-acetyltransferase (SAGA) complex and Mediator. Analysis of an authentic postrecruitment-regulated gene (CYC1) reveals that SAGA occupies the promoter under both uninduced and induced conditions. In contrast, Mediator is recruited only after transfer to inducing conditions and correlates with activation of the preloaded polymerase at CYC1. These studies indicate the critical functions of SAGA and Mediator in the mechanism of activation of genes with rate-limiting steps after recruitment of TBP.
Generic concepts in the Batocrinidae Wachsmuth and Springer, 1881 (class Crinoidea)
Authors: Ausich William I. , Kammer Thomas W. 
Published: January 2010

The Batocrinidae was a component of the North America Early Mississippian crinoid fauna and a significant contributor to the global biodiversity spike referred to as the “Age of Crinoids.” All batocrinids are North American, and all but one species are confined to the Tournaisian and Visean. In this contribution, genera are objectively defined on discrete characters, and the generic assignment of all valid species is re-evaluated. A phylogenetic hypothesis is presented for relationships within the Batocrinidae based on parsimony-based analyses and known stratigraphic ranges.Fifteen basic batocrinid architectural designs are recognized as genera, and four new genera are described:Glannearycrinusn. gen.,Gongylocrinusn. gen,Magnuscrinusn. gen., andSimatocrinusn. gen.Batocrinuswas a catch-all genus for any Mississippian camerate with tetragonal first primibrachials and an anal tube; thus, many late 19thcentury species are in need of a modern generic assignment. In this contribution, 61 percent of the 166 currently valid batocrinid species are reassigned to different genera. In addition,Sunwaptacrinusis transferred to the Batocrinidae, six species are transferred out of the Batocrinidae, and five species are designated as nomina dubia.
Equation of state of asymmetric nuclear matter: a VMC study
Authors: Manisa Kaan , Atav Ülfet , Sarıaydın Sibel 
Published: January 2010

Abstract
A Variational Monte Carlo (VMC) method is employed to investigate the properties of symmetric and asymmetric nuclear matter. The realistic Urbana V
14 twonucleon interaction potential of Lagaris and Pandharipande was used to describe the microscopic interactions. Also, many body interactions are included as a density dependent term in the potential. Total kinetic and potential energies per particle are calculated for asymmetric nuclear matter by VMC method at various densities and isospin asymmetry parameters. The results are compared with data found in literature, and it was observed that the results obtained in this study reasonably agree with the results found in the literature. Also, the symmetry energy and incompressibility factor of the nuclear matter were obtained. The results obtained are in good agreement with those obtained by various authors with different methods and techniques.
Amisulpride Versus Olanzapine in the Treatment of Schizophrenia in Indian Patients: Randomized Controlled Trial
Authors: Bhowmick Subhrojyoti , Hazra Avijit , Ghosh Malati 
Published: January 2010

Objective: Atypical antipsychotics are increasingly drugs of first choice in schizophrenia. Amisulpride, a new atypical antipsychotic, is reported to be effective for both positive and negative symptoms of schizophrenia in Western countries but Indian experience is limited. The aim of the present study was therefore to conduct a trial of amisulpride versus olanzapine in Indian schizophrenia patients. Methods: Eighty adult patients of either sex were randomized to receive standard doses of the two drugs orally, in a single blind manner, for 12 weeks, with follow up at 4 and 8 weeks. Effectiveness was assessed by changes in scores on the Brief Psychiatric Rating Scale (BPRS), Scale for Assessment of Positive Symptoms (SAPS), Scale for Assessment of Negative Symptoms (SANS), and physician-administered Clinical Global Impression (CGI) scale. Tolerability was assessed by treatment-emergent adverse drug reactions (ADRs). Results: Evaluable were 39 patients on amisulpride and 38 on olanzapine. The groups were comparable at baseline with respect to demographics, illness duration and rating scores. Final BPRS score was lower for olanzapine (33.2 ± 9.44) than for amisulpride (37.7 ± 9.67). SAPS and SANS scores and CGI rating improved individually in both arms but remained comparable between groups throughout the study period, but olanzapine reduced SAPS score to a greater extent. ADRs were encountered in 67.5% and 47.5% of patients (p = 0.113) on amisulpride and olanzapine, respectively. Tremor and insomnia were more frequent with amisulpride, while olanzapine caused more weight gain and sedation. No serious ADRs occurred. Conclusions: Amisulpride, although comparable to olanzapine on some measures, did not match the improvement seen with the latter drug in BPRS and SAPS scores. Despite differences in ADR profiles, overall tolerability was satisfactory for both drugs. In Indian patients, amisulpride should therefore be an alternative to olanzapine to a limited extent, such as when weight gain and sedation are undesirable.
A Comparison of Radiograph Analysis and Bark Dissection in Estimating Numbers of Western Pine Beetle
Authors: DeMars C. J. 
Published: January 2010

AbstractEstimates of the numbers of the western pine beetle, Dendroctonus brevicomis LeConte, in Pinus ponderosa Laws, bark samples were made by radiographs of 25 bark samples and by dissection counts of the bark. High correlations (r = >.9) between the two methods were found for (a) live larvae, (b) live plus dead larvae, (c) live of all stages combined, and (d) live plus dead of all stages combined. The bark dissection method took eight times as long and was 4⅓ times as expensive as the radiographic interpretation method of estimating bark beetle numbers.
Habituation and Associative Learning inDrino bohemicaMesn. (Diptera: Tachinidae)
Authors: Monteith L. G. 
Published: January 2010

AbstractAdults ofDrino bohemicaMesn., a tachinid parasite, learned to associate the movement of a part of their cage with the presence of host larvae. The parasites became habituated to an artist’s brush. Learning was retained for a period varying from a few hours to a few days. There were differences in the ability of groups of parasites to learn and to retain learning. The ability of the parasite to learn a new clue for use in locating hosts would interact with other factors that influence host-finding and host selection.
Heptachlor as a Systemic Insecticide against the Wheat Stem Sawfly, Cephus cinctus Nort.
Authors: Holmes N. D. , Peterson L. K. 
Published: January 2010

AbstractGranular heptachlor applied with the seed caused mortality in larvae of the wheat stem sawfly, Cephus cinctus Nort., in wheat stems. Half a pound of actual heptachlor per acre gave less control than either 1 or 2 pounds, although the latter two rates did not differ in effectiveness. Formulations with attaclay were more effective than with vermiculite.The insecticide was most effective in the lower internodes of the stem where it caused considerable mortality of early-instar larvae but was less effective on more mature larvae.To be effective, heptachlor evidently required light sawfly infestations restricted mainly to the lower internodes of the stems such as had occurred in 1960. In that year heptachlor gave its best control although it was no more effective than a moderately sawfly-resistant wheat. Lack of control in 1961 was related to the heavy sawfly infestations in that year. The poor control in 1962 was related to the concentration of most of the sawfly eggs in the top two internodes where the insecticide had little effect on newly-hatched larvae. Only later, when they were more mature, did the larvae reach the lower internodes.
Survey of Biota Associated with Monochamus (Coleoptera: Cerambycidae) in Maine.
Authors: Soper R. S. , Olson R. E. 
Published: January 2010

AbstractThe biota associated with Monochamus species collected in Maine include species of Acarina, Diptera, Hymenoptera and Nematoda, as well as fungal and bacterial pathogens.Mites belonging to seven families and thirteen genera were found in association with the sawyers. Two species were previously unknown and have since been described as the new genus and species Longoseius cuniculus Chant of the family Digamasellidae and the new genus and species Mucroseius monochami Lindquist of the family Blattisocidae. Parasitic diptera belonged to three genera in three different families, and of these one contained a new species, Forcipomyia innom., family Ceratopogonidae, which was found as an intermittent parasite of adult Monochamus notatus and Monochamus scutellatus. This constitutes a new host record for the biting midge family. Only one hymenopterous parasite, a species of Dolichomitus was reared from a sawyer larva. The five genera of nematodes isolated from larvae, pupae, and adults of Monochamus species include specimens of the genus Hexamermis. Parasitism by this group is thought to be unusual because of the relative inaccessibility of the host. Isolates from eight fungal genera were obtained, and strains of Beauveria bassiana, and Isaria farinosa, were shown to be pathogenic. The bacteria isolated from dead sawyers included Aerobacter aerogenes, Bacillus cereus var. mycoides, and one unidentified species. Only the tachinid E. monohammi and the mite Uropoda have been previously reported of the large number of organisms found associated with sawyer beetles in this study. The fungus Beauveria bassiana proved to be the most important biological control agent.
Predatory Behavior of Philodromus rufus Walckenaer (Araneae: Thomisidae)
Authors: Haynes Dean L. , Sisojević P. 
Published: January 2010

AbstractFactors which influence the rate at which Philodromus rufus Walckenaer attacks prey are discussed. Drosophila melanogaster Meign. was used as prey throughout the rearing and testing of P. rufus. Spiders used in these tests were immature at the time of capture and reared to the adult stage in the laboratory. Feeding histories were maintained for all spiders, although the experiments designed to measure the attack response of individual spiders to changing prey density were done with adult males.In the immature stage there was no difference between the feeding rate of male and female spiders. The adult males, however, were relatively inefficient predators; females killed approximately six times as many flies in their adult lives as males. The irregular feeding pattern of the females, as compared to the fairly uniform feeding pattern of the males, resulted in the males being more amenable to experimental tests. Periods of starvation, molting, and opposition strongly influenced the feeding rate of P. rufus. At high prey densities there was an inverse relationship between hunger and utilization of individual prey. This resulted from uncaptured prey interfering with the feeding spider.Both feeding time and searching time showed a relationship to prey density. Individual fly activity increased with fly density and this resulted in a functional response curve with an increasing slope. One of the basic requirements for regulation was thereby demonstrated. When prey density was corrected for the increase in fly activity by computing a new density estimate based on fly activity, a typical functional response for invertebrates became evident for hungry spiders but not for well-fed spiders. By using Holling's “disc equation” the difference between starved and satiated spiders was explained as an interaction between prey and predator characteristics. Owing to density-dependent parameters such as prey activity, predator feeding time, and “rate of discovery”, no known mathematical model fitted the data.
Synopsis of the Genus Tetraphleps Fieber in North America (Hemiptera: Anthocoridae)
Authors: Kelton Leonard A. 
Published: January 2010

AbstractSpecies of Tetraphleps Fieber known from North America are canadensis Prov., pilosipes Kelt. and And., feratis (Dr. and Har.), latipennis Van D., and uniformis Parsh. Descriptions, host plants, and distributional records for the species are given, and a key is provided.
Birch Pollen Immunotherapy Leads to Differential Induction of Regulatory T Cells and Delayed Helper T Cell Immune Deviation
Authors: Möbs Christian , Slotosch Caroline , Löffler Harald , Jakob Thilo , Hertl Michael , Pfützner Wolfgang 
Published: January 2010

Abstract
Correction of an imbalance between allergen-specific T cell subsets is considered a critical event in establishing allergen tolerance by specific immunotherapy (SIT). In a comprehensive, longitudinal study, distinct T cell populations and Ig subtypes were analyzed in subjects allergic to birch pollen during decisive time points of SIT (i.e., induction and maintenance phase), as well as in and out of birch pollen season. An increase in Bet v 1-specific, IL-10–secreting T cells, fulfilling the criteria of inducible type 1 regulatory T (Tr1) cells, was observed by the end of the induction phase; this resulted in a decreased ratio of allergen-specific IL-5+ Th2/Tr1 cells. In contrast, CD4+CD25+CD127low regulatory T cell numbers did not change. Furthermore, enhanced concentrations of allergen-specific IgG Abs were observed, whereas allergen-specific IgE and IgA levels remained unchanged. After 1 y of SIT, a reduced ratio of allergen-specific Th2/IFN-γ+ Th1 cells was apparent. Although untreated and SIT-treated allergic subjects developed enhanced Th2 cell responses during birch pollen season, only SIT-treated patients experienced elevated numbers of allergen-specific Tr1 cells, which were associated with reduced skin prick test reactivity and diminished clinical symptoms. In coculture assays, allergen-specific Tr1 cells showed an IL-10– and dose-dependent inhibition of CD4+CD25− T effector cells. Thus, SIT has differential effects on regulatory T cell subsets, resulting in an early induction of allergen-specific Tr1 cells associated with an increase in allergen-specific IgG, and it leads to a delayed shift from an allergen-specific Th2- to a Th1-dominated immune response.
Testing the developmental distinctiveness of male proactive and reactive aggression with a nested longitudinal experimental intervention
Authors: Barker Edward D. , Vitaro Frank , Lacourse Eric , Fontaine Nathalie M. G. , Carbonneau Rene , Tremblay Richard E. 
Published: January 2010

AbstractAn experimental preventive intervention nested into a longitudinal study was used to test the developmental distinctiveness of proactive and reactive aggression. The randomized multimodal preventive intervention targeted a subsample of boys rated disruptive by their teachers. These boys were initially part of a sample of 895 boys, followed from kindergarten to 17 years of age. Semiparametric analyses of developmental trajectories for self‐reported proactive and reactive aggression (between 13 and 17 years of age) indicated three trajectories for each type of aggression that varied in size and shape (Low, Moderate, and High Peaking). Intent‐to‐treat comparisons between the boys in the prevention group and the control group confirmed that the preventive intervention between 7 and 9 years of age, which included parenting skills and social skills training, could impact the development of reactive more than proactive aggression. The intervention effect identified in reactive aggression was related to a reduction in self‐reported coercive parenting. The importance of these results for the distinction between subtypes of aggressive behaviors and the value of longitudinal‐experimental studies from early childhood onward is discussed. Aggr. Behav. 36:127–140, 2010. © 2010 Wiley‐Liss, Inc.
Improved‐Performance Dye‐Sensitized Solar Cells Using Nb‐Doped TiO2 Electrodes: Efficient Electron Injection and Transfer
Authors: Lü Xujie , Mou Xinliang , Wu Jianjun , Zhang Dingwen , Zhang Linlin , Huang Fuqiang , Xu Fangfang , Huang Sumei 
Published: January 2010

AbstractWell‐crystallized Nb‐doped anatase TiO2 nanoparticles are prepared by a novel synthetic route and successfully used as the photoanode of dye‐sensitized solar cells (DSSCs). The homogenous distribution of Nb in the TiO2 lattice is confirmed by scanning transmission electron microscopy (STEM) elemental mapping and line‐scanning analyses. After Nb doping, the conductivity of the TiO2 powder increases, and its flat‐band potential (Vfb) has a positive shift. The energy‐conversion efficiency of a cell based on 5.0 mol% Nb‐doped TiO2 is significantly better, by about 18.2%, compared to that of a cell based on undoped TiO2. The as‐prepared Nb‐doped TiO2 material is proven in detail to be a better photoanode material than pure TiO2, and this new synthetic approach using a water‐soluble precursor provides a simple and versatile way to prepare excellent photoanode materials.
Heritability estimates for cognitive factors and brain white matter integrity as markers of schizophrenia
Authors: Bertisch Hilary , Li Dawei , Hoptman Matthew J. , DeLisi Lynn E. 
Published: January 2010

AbstractRecent genetics research focusing on schizophrenia has led to candidate cognitive and neuroimaging variables as intermediate phenotypes or “endophenotype” markers for the illness. Among other stringent criteria, to be an endophenotype, a marker must demonstrate heritability. In an effort to explore the validity of a selection of cognitive and neuroimaging endophenotypes, the present study was designed to determine estimates of their heritability. One hundred fourteen subjects, including 27 with schizophrenia and 39 unaffected relatives from 23 multiplex schizophrenia families, participated in a comprehensive neuropsychological test battery and structural brain imaging with diffusion tensor imaging (DTI). Variables were selected if they previously have been demonstrated to show differences between people with schizophrenia and normal controls. Significant evidence of heritability was confirmed for overall cognitive function (“g”), as well as expressive and receptive language, verbal and visual memory, processing speed and cognitive inhibition. In addition, significant heritability estimates were determined for specific regions in the frontal, central, parietal, and occipital areas. These results suggest that the variables chosen may be useful endophenotypes for genetic and early detection studies, although further work with larger cohorts should be conducted to show that deficits in these functions and structures also segregate with schizophrenia within families and thus fully satisfy the definition of an endophenotype. In addition, other cognitive and neuroimaging variables that were not studied here may be candidates for schizophrenia endophenotypes. © 2010 Wiley‐Liss, Inc.
Brief communication: Tissue isotopic enrichment associated with growth depression in a pig: Implications for archaeology and ecology
Authors: Warinner Christina , Tuross Noreen 
Published: January 2010

AbstractStressors such as fasting or poor diet quality are thought to potentially alter the nitrogen and carbon isotopic values of animal tissues. In this study, we demonstrate an inverse correlation between growth rate and multiple tissue enrichment of δ15N, δ13C, and, to a lesser degree, δ18O in a juvenile pig. A more complex pattern is observed with respect to tissue δD and growth rate. The observed association between growth rate and tissue isotopic fractionation has important implications for paleodietary and migratory reconstructions of archaeological populations that may have been affected by famine, malnutrition, seasonal variation in food availability, and/or other factors that can affect childhood growth rates. Am J Phys Anthropol 2010. © 2010 Wiley‐Liss, Inc.
Copper‐catalyzed/mediated aromatic CH bond functionalization
Authors: Zhang Ming 
Published: January 2010

AbstractThe CH functionalization strategy has received substantial attention because of its economic, sustainable and environmentally benign features. Most reports are on palladium, rhodium or ruthenium catalysis, and reports on copper catalysis are relatively fewer. Recently, many reports on copper‐catalyzed/mediated CH functionalization have been published. Copper salts bear properties of cheapness and relatively low toxicity. This review introduces an advance on copper‐catalyzed/mediated aromatic CH functionalization. The content includes aromatic ring CH bond functionalization and heteroaromatic CH bond functionalization forming new carbon–carbon or carbon–heteroatom bonds. Copyright © 2010 John Wiley & Sons, Ltd.