bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using retrospective reports to develop profiles of harmful versus playful teasing experiences
Authors: Andrews Naomi C. Z. , Dawes Molly 
Published: June 2024

AbstractIntroductionThe current investigation's central goal was to elucidate the complex features of peer teasing episodes that individuals use to interpret teasing as harmful versus playful.MethodIn 2022–2023, we used semistructured interviews to gather retrospective reports of K‐12 peer teasing experiences from a sample of 27 students from a university in southern Ontario, Canada (18–25 years old, 63% female, 78% White).ResultsContent analysis revealed the multifaceted nature of teasing, with participants defining teasing as harmful, playful, or including elements of both harm and pleasure. Harmful teasing experiences often included content that was sensitive to the target, occurred between both friends and nonfriends, and often included a power differential with the teasing perpetrator having more power than the target. Targets recalled negative emotional responses, with behavioral responses to mitigate the situation and reduce further teasing. In contrast, playful teasing often occurred between friends or close friends, was often motivated by positive interpersonal motives (e.g., for encouragement), and had positive impacts on the relationship between perpetrator and target. However, despite benign intent, some playful teasing was marked by negative emotional responses and feelings of harm.ConclusionsResults have implications for uncovering the nuanced and complex nature of teasing, and provide a preliminary profile of harmful versus playful teasing interactions.
Exchange‐correlation effects in interatomic energies for pure density functionals and their application to the molecular energy prediction
Authors: Tognetti Vincent , Joubert Laurent 
Published: June 2024

AbstractIn this proof‐of‐concept paper, we show how exchange‐correlation effects can be simply recovered for interatomic energies within the interacting quantum atoms decomposition when local, gradient generalized, or meta‐gradient generalized approximations are used in density functional theory (DFT) calculations. We also demonstrate how inhomogeneity and non‐local effects can be introduced even from a pure local scheme, without resorting to any orbital information. Finally, we provide numerical evidence on a database of selected energetic molecules that this decomposition scheme can be efficiently used to build accurate models for the prediction of molecular energies from an initial “cheap” DFT calculation.
Ionic liquids intercalation in titanium carbide MXenes: A first‐principles investigation
Authors: Zhang Shaoze , Jiang De‐en , Zhou Nan , Tang Jiaxing , Zhang Keyu , Li Yin , Hu Junxian , Peng Changjun , Liu Honglai , Yang Bin , Yao Yaochun 
Published: June 2024

AbstractHerein, we present a density functional theory with dispersion correction (DFT‐D) calculations that focus on the intercalation of ionic liquids (ILs) electrolytes into the two‐dimensional (2D) Ti3C2Tx MXenes. These ILs include the cation 1‐ethyl‐3‐methylimidazolium (Emim+), accompanied by three distinct anions: bis(trifluoromethylsulfonyl)imide (TFSA−), (fluorosulfonyl)imide (FSA−) and fluorosulfonyl(trifluoromethanesulfonyl)imide (FTFSA−). By altering the surface termination elements, we explore the intricate geometries of IL intercalation in neutral, negative, and positive pore systems. Accurate estimation of charge transfer is achieved through five population analysis models, such as Hirshfeld, Hirshfeld‐I, DDEC6 (density derived electrostatic and chemical), Bader, and VDD (voronoi deformation density) charges. In this work, we recommend the DDEC6 and Hirshfeld‐I charge models, as they offer moderate values and exhibit reasonable trends. The investigation, aimed at visualizing non‐covalent interactions, elucidates the role of cation‐MXene and anion‐MXene interactions in governing the intercalation phenomenon of ionic liquids within MXenes. The magnitude of this role depends on two factors: the specific arrangement of the cation, and the nature of the anionic species involved in the process.
Chronological alterations in de novo malignancies after living‐donor liver transplantation: A cohort study of 1781 recipients using annual comparisons of standardized incidence ratios
Authors: Tajima Tetsuya , Hata Koichiro , Tanaka Kosuke , Iyama Naomi , Kusakabe Jiro , Kageyama Shoichi , Ogawa Eri , Okamoto Tatsuya , Haga Hironori , Uemoto Shinji , Hatano Etsuro 
Published: June 2024

AbstractBackgroundDe novo malignancies (DNMs) are a major adverse event after solid organ transplantation; however, their characteristics and recent trends after living‐donor liver transplantation (LDLT) remain unclear.MethodsWe retrospectively reviewed 1781 primary LDLT recipients (1990–2020) and annually calculated standardized incidence ratios (SIRs) of DNMs compared to the age‐adjusted Japanese general population.ResultsAfter 21 845 person‐years follow‐up, 153 DNM lesions (8.6%) were identified in 131 patients (7.4%). The incidence was 0.007 person‐years. DNMs included 81 post‐transplant lymphoproliferative disorders (PTLDs), 14 colorectal, 12 lung, and 12 gastric cancers, and so on. Comorbid DNMs significantly worsened recipient survival than those without (p < .001). The 5‐ and 10‐year recipient survival after DNM diagnosis were 65% and 58%, respectively. Notably, SIR1993–1995: 8.12 (95% CI: 3.71–15.4, p < .001) and SIR1996–1998: 3.11 (1.34–6.12, p = .01) were significantly high, but had decreased time‐dependently to SIR2005–2007: 1.31 (0.68–2.29, p = .42) and SIR2008–2010: 1.34 (0.75–2.20, p = .33), indicating no longer significant difference in DNMs development. Currently, however, SIR2014–2016: 2.27 (1.54–3.22, p < .001) and SIR2017–2019: 2.07 (1.40–2.96, p < .001) have become significantly higher again, reflecting recent aging of recipients (>50 years) and resultant increases in non‐PTLD DNMs. Furthermore, characteristically in LDLT, the fewer the donor‐recipient HLA‐mismatches, the less the post‐transplant DNMs development.ConclusionDNM development after LDLT was significantly higher than in the general population due to higher PTLD incidence (1993‐1998), but once became equivalent (2005‐2013), then significantly increased again (2014‐2019) due to recent recipient aging and resultant increase in solid cancers.
A Statovirus‐like virus from respiratory tracts of patients, China
Authors: Song Ke , Ye Run‐Ze , Li Yu‐Yu , Gong Cheng , Xia Luo‐Yuan , Gao Wan‐Ying , Wang Zhen‐Fei , Wang Ning , Cheng Nuo , Zhang Ming‐Zhu , Du Yi‐Di , Xie Hui , Zhu Dai‐Yun , Shi Wenqiang , Li Mao‐Zhong , Zhao Lin , Jia Na , Jiang Jia‐Fu , Cui Xiao‐Ming , Huang Fang , Cao Wu‐Chun 
Published: June 2024

AbstractThe emerging evidence of human infections with emerging viruses suggests their potential public health importance. A novel taxon of viruses named Statoviruses (for stool‐associated Tombus‐like viruses) was recently identified in the gastrointestinal tracts of multiple mammals. Here we report the discovery of respiratory Statovirus‐like viruses (provisionally named Restviruses) from the respiratory tracts of five patients experiencing acute respiratory disease with Human coronavirus OC43 infection through the retrospective analysis of meta‐transcriptomic data. Restviruses shared 53.1%–98.8% identities of genomic sequences with each other and 39.9%–44.3% identities with Statoviruses. The phylogenetic analysis revealed that Restviruses together with a Stato‐like virus from nasal‐throat swabs of Vietnamese patients with acute respiratory disease, formed a well‐supported clade distinct from the taxon of Statoviruses. However, the consistent genome characteristics of Restviruses and Statoviruses suggested that they might share similar evolutionary trajectories. These findings warrant further studies to elucidate the etiological and epidemiological significance of the emerging Restviruses.
Surface contamination of cytotoxic medicine in preparation and patient care areas in Australian hospitals: a retrospective cross‐sectional study
Authors: Woodward Vincent , Panjarjian Meghrie , Devi Devika , Hanrahan Jane , Soriano Michael , Roper Matt , Musa Hala , Davies Stephanie , Samios Peter , Teh Michael , Barclay Peter , Naughtin Clare , Vaillancourt Régis , Nikolaidis Carl , Pelland Bryan , Penm Jonathan 
Published: June 2024

AbstractBackgroundCytotoxic medicine contamination of preparation and administration areas of oncology healthcare facilities poses a risk to staff facing repeated low‐level exposure over time. The use of closed‐system transfer devices (CSTDs) during preparation and administration of cytotoxic products may reduce the levels of contamination. The primary aim was to determine the levels of cytotoxic medicine contamination in preparation and administration areas of hospitals that use CSTDs compared to those that do not.AimThe primary aim was to determine the levels of cytotoxic medicine contamination in preparation and administration areas of hospitals that use CSTDs compared to those that do not.MethodA retrospective, cross‐sectional study across four Australian hospitals was conducted. Cytotoxic medicine contamination was determined via surface wipe sampling on six specified surfaces. The samples were tested for cyclophosphamide, docetaxel, etoposide, ifosfamide, irinotecan, methotrexate, paclitaxel, pemetrexed, topotecan, and vinblastine. This project was exempt due to the local policy requirements that constitute research by the South Eastern Sydney Local Health District Human Research Ethics Committee (Reference no: ETH01899). The justification for this ethics exemption was as follows: this was a study involving sample testing only and did not include human participants or participation.ResultsEnvironmental contamination with cytotoxic medications was observed at all hospitals, regardless of the CSTD used. Of the 24 samples tested, the agent most frequently seen was ifosfamide with 29% (n = 7), followed by cyclophosphamide 13% (n = 3), and methotrexate 8% (n = 2). There was no statistically significant difference between hospitals that used CSTDs compared to hospitals that did not (25% vs 42%, p = 0.67). Contamination was more extensive in preparation areas than administration areas, and was observed on the biological safety cabinets (BSC) worktop, packaging bench, and floor in front of the BSCs.ConclusionAll sites had contamination present for cytotoxic medicines. There was no statistically significant difference in the proportion of contaminated surfaces between sites that used CSTDs versus sites where CSTDs were not used. Only ifosfamide contamination was identified in pharmacy areas that used CSTDs. Safe work practices and staff training are encouraged to further minimise exposure risk.
High prevalence of syndromic hearing loss in Mexican children undergoing cochlear implantation
Authors: Rodriguez‐Valero Monica , Pastolero Adrian , Redfield Shelby , Medrano Alma , Abreu‐Gonzalez Melania , Gallardo‐Ollervides Jose Francisco , Cisneros Lesser Juan Carlos , Hinojosa Valencia Maria Fernanda , Poe Dennis , Shearer Eliot 
Published: June 2024

AbstractObjectiveStudies evaluating genetic sensorineural hearing loss (SNHL) in Hispanic and Latino populations using genomic technologies are lacking. Recent data has shown that Hispanic and Latino children display lower genetic diagnostic rates despite similar prevalence rates of SNHL to their Asian and White counterparts, thus negatively affecting their clinical care. Our objective was to determine the genetic contribution to SNHL in a population of Mexican children undergoing evaluation for cochlear implantation.MethodsPediatric patients from Mexico with severe to profound SNHL undergoing evaluation for cochlear implantation were recruited. Exome sequencing (ES) or hearing loss gene panel testing was performed. Variant pathogenicity was established in accordance to criteria established by the American College of Medical Genetics, and variants of interest were clinically confirmed via CLIA certified laboratory.ResultsGenetic evaluation was completed for 30 Mexican children with severe to profound SNHL. A genetic cause was identified for 47% (14) of probands, and 7% (2) probands had an inconclusive result. Of the diagnoses, 10 (71%) were syndromic or likely syndromic, and 4 (29%) were nonsyndromic. Eight probands (80% of all syndromic diagnoses) were diagnosed with a syndromic form of hearing loss that mimics a nonsyndromic clinical presentation at a young age and so could not be suspected based on clinical evaluation alone without genetic testing.ConclusionThis is the largest study to date to use comprehensive genomic testing for the evaluation of Mexican children with severe to profound SNHL. A significant proportion of children in this cohort were diagnosed with syndromic hearing loss. Future study in a larger cohort of Mexican children with varying degrees of hearing loss is required to improve the efficacy of genetic testing and timely medical intervention within these ethnically diverse populations.Level of evidenceLevel 4 (cohort study).
A Coordinating Small Organic Molecule with Tunable Lower Critical Solution Temperature for Efficient Management of Solar Radiation
Authors: Zhou Junnan , Yuan Weidong , Qing Yuxi , Du Guangyan , Li Quan 
Published: June 2024

AbstractStructurally well‐defined small molecules with lower critical solution temperature (LCST) behavior offer enormous prospects for fine‐tuning their phase transition properties to be “on‐demand” applied in the specific scene but are still underexplored. Herein, a novel amphiphilic small LCST molecule is rationally designed and synthesized. The molecule, namely TG, features a conjugation of multiple short ethylene glycol (EG) chains with the functional coordinating terpyridine (Tpy) moiety. The molecule TG demonstrates excellent LCST behavior down to 0.05 × 10−3 m in a water solution. And a cloud point Tcp = 30.9 °C with a very short thermal hysteresis ΔT = 0.2 °C and good reversibility can be achieved when c = 0.1 × 10−3 m. The excellent LCST properties of TG have enabled its successful performance as the smart window for solar radiation management with the ∆Tlum, ∆TIR, and ∆Tsol being 83.6%, 49.1%, and 67.2%, respectively. Moreover, the presence of Tpy moiety in TG enables its coordination with Ru3+ and the resulting complex also exhibits modulated LCST behavior with different concentration‐dependent Tcp. These studies would provide novel small‐molecule‐based scaffolds for constructing better solar radiation management systems as well as other thermal‐responsive smart materials.
Extracorporeal shockwave therapy in treatment of chronic prostatitis/chronic pelvic pain syndrome: Systematic review and meta‐analyses
Authors: Labetov Ivan , Vaganova Anastasia , Kovalev Gleb , Shkarupa Dmitry 
Published: June 2024

AbstractAimsChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) prevalence varies from 8.4% to 25% of the male population and is associated with diminished health‐related quality of life. Managing CP/CPPS remains challenging and there is not any common option to treat all patients effectively because of the complex disease nature. The currently available data for the extracorporeal shockwave therapy (eSWT) effect on pain relief and well‐being were analyzed in the present study.MethodsWe adhered to PRISMA 2022 guidelines for reporting the quantitative and qualitative data synthesis. A literature search was conducted in March 2023 using PubMed/Medline, Scopus, and Google Scholar. Randomized prospective studies of eSWT alone or eSWT plus conventional medicinal treatment were included. The risk of bias was estimated using the RoB 2.0. Primary outcomes were self‐reported scores, including the NIH‐CPSI questionnaire and VAS, at 1 month or 2, 3, and 6, months follow‐up.ResultsThe CP/CPPS patients who receive eSWT have more pronounced pain relief and improvement of other subjective NIH‐CPSI scores compared with control groups that received placebo or medication therapy. The effect of eSWT seems to be long‐lasting and was confirmed in the 6‐month follow‐up (p < 0.01).ConclusionsBased on the meta‐analysis of accessible studies, we receive the equivalence eSWT applicability for the CP/CPPS treatment and can be offered to patients because of its noninvasiveness, high level of safety, and successful clinical results demonstrated in this analysis.
Getting linear time in graphs of bounded neighborhood diversity
Authors: Cordasco Gennaro , Gargano Luisa , Rescigno Adele A. 
Published: June 2024

AbstractParameterized complexity, introduced to efficiently solve NP‐hard problems for small values of a fixed parameter, has been recently used as a tool to speed up algorithms for tractable problems. Following this line of research, we design algorithms parameterized by neighborhood diversity () for several graph theoretic problems in : Maximum ‐Matching, Triangle Counting and Listing, Girth, Global Minimum Vertex Cut, and Perfect Graphs Recognition. Such problems are known to admit algorithms parameterized by modular‐width () and consequently—as is a special case of —by . However, the proposed novel algorithms allow for improving the computational complexity from time —where and denote, respectively, the number of vertices and edges in the input graph—to time which is only additive in the size of the input. Then we consider some classical NP‐hard problems (Maximum independent set, Maximum clique, and Minimum dominating set) and show that for several classes of hereditary graphs, they admit linear time algorithms for sufficiently small—nonnecessarily constant—values of the neighborhood diversity parameter.
Isolation, screening, and characterization of polyhydroxyalkanoate (PHA)‐producing Cellulosimicrobium cellulans: A promising approach for eco‐friendly biopolymer production
Authors: Mahajan Megha , Gokilalakshmi Shanmugaselvam , Balavaishnavi Balasubramanian , Kamaraj Murugesan , Nithya T. G. , Govarthanan M. 
Published: June 2024

AbstractThe replacement of synthetic plastics with eco‐friendly biopolymers is a notable approach in the modern world. Polyhydroxyalkanoates (PHAs) have gained a lot of attention among researchers in recent decades. This study aimed to isolate and screen microorganisms capable of producing PHA from composite samples. Several composting unit samples were collected and used to isolate 15 distinct colonies which were then screened for PHA synthesis. Three isolates‐SS2, SSNA 1a, and SF2‐showed promising PHA production. Among these isolates, SS2 had the highest PHA content of 70.1%. The isolate SS2 was determined as Cellulosimicrobium cellulans DSM 43879 by gene sequencing. The polymer produced by SS2 was further characterized. The presence of carbonyl groups and ester linkages in the PHA polymer was established by Fourier transform infrared analysis. The polymer's crystalline nature was validated by X‐ray powder diffraction measurement. Scanning electron microscope study revealed thread‐like forms with a rough surface while energy dispersive X‐ray analysis revealed a low impurity content that was primarily composed of carbon and oxygen with traces of other elements. Overall, the findings indicate C. cellulans potential as an ideal candidate for efficient PHA synthesis supporting its commercial potential in diverse applications.
Beyond driver mutations: exploring the landscape of mutational signatures in adenocarcinomas of the bladder†
Authors: Szarvas Tibor , Reis Henning 
Published: June 2024

AbstractThe emergence of mutational signatures in cancer research represents a paradigm shift, offering profound insights into tumor biology, therapeutic strategies, and risk assessment. A recent article published in The Journal of Pathology delves into the significance of mutational signatures, assessing their role as molecular fingerprints that illuminate the etiology of individual cancer cases. By deciphering the diverse patterns of DNA alterations, in the context of urachal and nonurachal bladder adenocarcinomas, researchers can unravel intrinsic and environmental risk factors shaping cancer development. The study highlighted a predominance of environmental risk factors in Chinese populations affected by bladder adenocarcinomas. In this context, in this commentary, we highlight some of the potential applications of molecular signatures in differential diagnosis and therapy prediction. As the field continues to evolve, a deeper understanding of mutational signatures promises to revolutionize precision oncology by offering personalized approaches informed by comprehensive mutational patterns of tumors. © 2024 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
A novel post‐forming method for fully cured thermosetting composite parts: Prediction and investigation
Authors: Sun Lishuai , Xie Chenyang , Liu Chuang , Wang Junbiao 
Published: June 2024

AbstractThe objective of this work is to devise a post‐forming technique capable of accurately and significantly altering the shape of fully cured thermosetting composite parts. To accomplish this goal, the viscoelastic behavior and resulting deformation of fully cured parts at elevated temperatures were predicted and examined using viscoelastic mechanics, finite element analysis (FEA), surrogate modeling, and the particle swarm optimization (PSO) method. Firstly, the mechanism of fully cured parts' shape adjustment based on viscoelastic mechanics was introduced, and a method was established for the inverse identification of the stress relaxation ratio in the different directions of material. Secondly, an FEA model for predicting post‐forming was developed based on the standard linear‐solid viscoelastic model. A dataset was then compiled using parameterized FEA to train a rapid prediction model for post‐forming. The influence of various forming and structural parameters on the post‐forming process was examined. The results indicate that layup has the most significant impact, followed by displacement and temperature. The radial basis function was selected to construct the precise surrogate model after comparing it with the Kriging model and the Response Surface Methodology (RSM) model. Ultimately, to achieve the desired shape after post‐forming, the PSO method can be employed to determine the ideal combination of forming parameters.Highlights
The post‐forming method could adjust the shape of fully cured composites.
The mechanism of post‐forming is based on viscoelastic behavior.
An accurate FEA based on the standard linear‐solid model was established.
The radial basis function was developed for quick and precise prediction.
The particle swarm optimization could obtain the ideal forming parameters.