bluuebunny/crossref_metadata_2025_split huggingface dataset:
Congenital generalized lipodystrophy, type 4 (CGL4) associated with myopathy due to novel PTRF mutations
Authors: Shastry Savitha , Delgado Mauricio R. , Dirik Eray , Turkmen Mehmet , Agarwal Anil K. , Garg Abhimanyu 
Published: August 2010

AbstractCongenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near total absence of body fat since birth with predisposition to insulin resistance, diabetes, hypertriglyceridemia, and hepatic steatosis. Three CGL loci, AGPAT2, BSCL2, and CAV1, have been identified previously. Recently, mutations in polymerase I and transcript release factor (PTRF) were reported in five Japanese patients presenting with myopathy and CGL (CGL4). We report novel PTRF mutations and detailed phenotypes of two male and three female patients with CGL4 belonging to two pedigrees of Mexican origin (CGL7100 and CGL178) and one pedigree of Turkish origin (CGL180). All patients had near total loss of body fat and congenital myopathy manifesting as weakness, percussion‐induced muscle mounding, and high serum creatine kinase levels. Four of them had hypertriglyceridemia. Three of them had atlantoaxial instability. Two patients belonging to CGL178 pedigree required surgery for pyloric stenosis in the first month of life. None of them had prolonged QT interval on electrocardiography but both siblings belonging to CGL7100 had exercise‐induced ventricular arrhythmias. Three of them had mild acanthosis nigricans but had normal glucose tolerance. Two of them had hepatic steatosis. All patients had novel null mutations in PTRF gene. In conclusion, mutations in PTRF result in a novel phenotype that includes generalized lipodystrophy with mild metabolic derangements, myopathy, cardiac arrhythmias, atlantoaxial instability, and pyloric stenosis. It is unclear how mutations in PTRF, which plays an essential role in formation of caveolae, affect a wide variety of tissues resulting in a variable phenotype. © 2010 Wiley‐Liss, Inc.
Membrane‐Based Dairy Separation: A Comparison of Nanofiltration and Electrodialysis
Authors: Rice G. , Kentish S. , Vivekanand V. , O'Connor A. , Stevens G. , Barber A. 
Published: August 2010

AbstractTwo membrane technologies are compared for the separation of potentially valuable lactose and calcium from a currently underutilised dairy stream, i.e. whey ultrafiltration permeate. Nanofiltration, a pressure driven separation through a porous membrane, is able to simultaneously concentrate and demineralise this stream, giving up to 70% reduction in unwanted monovalent salts. Electrodialysis, an electrically driven separation of ions through ion exchange or porous membranes, is able to demineralise whey permeate to higher levels, but has lower selectivity between mono‐ and divalent ions. The technologies are evaluated with regard to membrane perm‐selectivity, efficiency, cost and suitability to the given separation, based upon research presented in the literature. It is concluded that nanofiltration offers the most potential for separation between undesirable monovalent ions and valuable divalent ions and lactose, while electrodialysis is more suitable for higher levels of demineralisation where a purer lactose product is required.
State feedback control for uncertain switched systems with interval time‐varying delay
Authors: Wang Limin , Shao Cheng , Liu Xuanyu 
Published: August 2010

AbstractStability criteria and hybrid controllers' design problems for a class of uncertain switched systems with interval time‐varying delay are considered in this paper. Based on the average dwell time method, by choosing a new appropriate Lyapunov‐Krasovskii functional which fully utilizes the information of both the lower and upper bounds of the interval time‐varying delay, new delay‐range‐dependent stability criteria and stabilization conditions are first derived in terms of linear matrix inequalities. Moreover, in order to obtain much less conservative results, a tighter bounding for some terms is estimated and no redundant matrix variable is introduced. Finally, two numerical examples are given to demonstrate the applicability and the effectiveness of the proposed method.Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Delay‐dependent stability and H∞ control of stochastic time‐delay systems with Markovian jumping parameters
Authors: Ma Li , Da Fei‐Peng , Wu Lingyao 
Published: August 2010

AbstractIn this paper, the mean‐square exponential stability and H∞ control problems are investigated for a general class of stochastic time‐delay systems with Markovian jumping parameters. First, a delay‐dependent result in terms of linear matrix inequalities (LMIs) for mean‐square exponential stability and H∞ performance analysis is presented by constructing a modified Lyapunov‐Krasovskii functional. The decay rate can be chosen in a range to be a finite positive constant without equation constraint. Then, based on the proposed stability result, we derive sufficient condition to solve the H∞ controller design problem. Finally, numerical examples are provided to illustrate the effectiveness of the theoretical results.Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
FPGA‐based adaptive dynamic sliding‐mode neural control for a brushless DC motor
Authors: Tsai Jang‐Zern , Hsu Chun‐Fei , Chiu Chien‐Jung , Peng Kai‐Lin 
Published: August 2010

AbstractIn the adaptive neural control design, since the number of hidden neurons is finite for real‐time applications, the approximation errors introduced by the neural network cannot be inevitable. To ensure the stability of the adaptive neural control system, a switching compensator is designed to dispel the approximation error. However, it will lead to substantial chattering in the control effort. In this paper, an adaptive dynamic sliding‐mode neural control (ADSNC) system composed of a neural controller and a fuzzy compensator is proposed to tackle this problem. The neural controller, using a radial basis function neural network, is the main controller and the fuzzy compensator is designed to eliminate the approximation error introduced by the neural controller. Moreover, a proportional‐integral‐type adaptation learning algorithm is developed based on the Lyapunov function; thus not only the system stability can be guaranteed but also the convergence of the tracking error and controller parameters can speed up. Finally, the proposed ADSNC system is implemented based on a field programmable gate array chip for low‐cost and high‐performance industrial applications and is applied to control a brushless DC (BLDC) motor to show its effectiveness. The experimental results demonstrate the proposed ADSNC scheme can achieve favorable control performance without encountering chattering phenomena.Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Evaluation of three spatial discretization schemes with the Galewsky et al. test
Authors: Shin Seoleun , Sommer Matthias , Reich Sebastian , Névir Peter 
Published: August 2010

AbstractWe evaluate the Hamiltonian particle methods (HPM) and the Nambu discretization applied to shallow‐water equations on the sphere using the test suggested by Galewsky et al. (2004). Both simulations show excellent conservation of energy and are stable in long‐term simulation. We repeat the test also using the ICOSWP scheme to compare with the two conservative spatial discretization schemes. The HPM simulation captures the main features of the reference solution, but wave 5 pattern is dominant in the simulations applied on the ICON grid with relatively low spatial resolutions. Nevertheless, agreement in statistics between the three schemes indicates their qualitatively similar behaviors in the long‐term integration. Copyright © 2010 Royal Meteorological Society
Protein changes in macrophages induced by plasma from rats exposed to 35 GHz millimeter waves
Authors: Sypniewska Roza K. , Millenbaugh Nancy J. , Kiel Johnathan L. , Blystone Robert V. , Ringham Heather N. , Mason Patrick A. , Witzmann Frank A. 
Published: August 2010

AbstractA macrophage assay and proteomic screening were used to investigate the biological activity of soluble factors in the plasma of millimeter wave‐exposed rats. NR8383 rat macrophages were incubated for 24 h with 10% plasma from male Sprague–Dawley rats that had been exposed to sham conditions, or exposed to 42 °C environmental heat or 35 GHz millimeter waves at 75 mW/cm2 until core temperature reached 41.0 °C. Two‐dimensional polyacrylamide gel electrophoresis, image analysis, and Western blotting were used to analyze approximately 600 protein spots in the cell lysates for changes in protein abundance and levels of 3‐nitrotyrosine, a marker of macrophage stimulation. Proteins of interest were identified using peptide mass fingerprinting. Compared to plasma from sham‐exposed rats, plasma from environmental heat‐ or millimeter wave‐exposed rats increased the expression of 11 proteins, and levels of 3‐nitrotyrosine in seven proteins, in the NR8383 cells. These altered proteins are associated with inflammation, oxidative stress, and energy metabolism. Findings of this study indicate both environmental heat and 35 GHz millimeter wave exposure elicit the release of macrophage‐activating mediators into the plasma of rats. Bioelectromagnetics 31:656–663, 2010. © 2010 Wiley‐Liss, Inc.
Assessment of the exposure to WLAN frequencies of a head model with a cochlear implant
Authors: Parazzini Marta , Sibella Federica , Paglialonga Alessia , Ravazzani Paolo 
Published: August 2010

AbstractIn the last few years, significant developments have taken place in the field of Wireless Local Area Networks (WLAN), and the popularity of portable devices supporting Wireless Fidelity (Wi‐Fi) is continuously growing. At the same time, the number of Active Implanted Medical Devices (AIMD) being placed in patients is widely increasing and among them, cochlear implants (CI) are becoming a common aid. The goal of this study is to investigate the effect on the electromagnetic field distribution and the specific absorption rate (SAR) due to the presence of a CI in a head model during far‐field exposure to Wi‐Fi frequencies. The head model was obtained by image segmentation, the implant was modelled as a geometric structure, and the exposure sources were modelled as a uniform plane wave (power density = 10 W/m2) at 2.4, 5.2 and 5.8 GHz. Vertical and horizontal polarizations were simulated. Conditions with and without CI were compared. The findings of that are: (1) local differences in the field distribution close to the CI, comparing the head models with or without the CI; (2) higher field strength and point SAR value in the cochlear region very close to the CI; (3) negligible differences in the field strength and point SAR value in the cochlear region far from the CI; (4) negligible variations in the average SAR values in the cochlea and head due to the presence of the CI. The results of this study conclude that insertion of a CI brings moderate localized differences in the E, H and point SAR distribution when evaluated close to the electrode array in the cochlea, while negligible differences are found in the average SAR values both in the cochlea and head, independent of frequency and wave polarization. Bioelectromagnetics 31:546–555, 2010. © 2010 Wiley‐Liss, Inc.
Demographic Knowledge and Nation‐Building: The Peruvian Census of 1940
Authors: Necochea López Raúl 
Published: August 2010

AbstractDemografisches Wissen und ‘Nation‐Building’: Der peruanische Zensus von 1940. Die Demografen, die 1940 die peruanische Volkszählung organisierten, stellten die zunehmende ethnische Heterogenität Perus als Zeichen aufbrechender kultureller Grenzen und als Symbol einer tragfähigen peruanischen Identität dar. Diese besondere demografische Dynamik war ihrer Ansicht nach ein Motor der nationalen Entwicklung. Dieser Aufsatz analysiert die verschiedenen Formen, in denen Demografen kulturelle Heterogenität als einen potentiellen Vorteil des Landes konstruierten. Hierdurch wird deutlich, wie akademisches Wissen über ethnische Hybridität mit den nationalistischen Projekten der zweiten Hälfte des 20. Jahrhunderts verbunden war. Er analysiert weiterhin den Einfluss, den die ideologischen Sympathien der peruanischen Demografen für den Sozialismus auf ihre wissenschaftliche Arbeit hatte.Demographic Knowledge and Nation‐Building: The Peruvian Census of 1940. The demographers who organized the 1940 census of Peru portrayed the increasingly mixed‐race Peruvian population as indicative of the breaking down of cultural barriers to the emergence of a robust Peruvian identity, a process that, they claimed, would lead to greater national development. This paper analyzes the ways in which demographers constructed cultural heterogeneity as a potential national asset. This reveals how scientific knowledge of miscegenation affected the formation of a nationalist project in the second half of the twentieth century, and also how demographers' ideological commitments to socialism shaped scientific practice.
Measuring the magnitude of internal motion in a complex hexasaccharide
Authors: Ganguly Soumya , Xia Junchao , Margulis Claudio , Stanwyck Liz , Bush C. Allen 
Published: August 2010

AbstractFor the development of a scheme for quantitative experimental estimation of internal motion in the complex human milk hexasaccharide lacto‐N‐di‐fuco hexose I (LNDFH I), we measured a large number of experimental residual dipolar couplings in liquid crystal orienting media. We present a total of 40 13C1H and 1H1H dipolar coupling values, each representing distinct directions of internuclear vectors. The NMR data were interpreted with established methods for analysis of rigid subdomains of the oligosaccharide as well as a novel method in which dipolar couplings were calculated over an ensemble of conformers from a solvent Molecular Dynamics trajectory using multiple linear regression analysis. The Lewisb epitope region of LNDFH I assumed a single unique conformation with internal motion described by fluctuations of 5–10° in glycosidic dihedral angles consistent with previous studies. Greater flexibility was observed for the remaining GlcNAc1→3‐β‐D‐Gal and β‐D‐Gal1→4Glc linkages, with the former glycosidic linkage existing in a conformational exchange among three states. The results were also supported by similar results of calculations carried out with conformers obtained from a simple Monte Carlo simulation without explicit solvent. © 2010 Wiley Periodicals, Inc. Biopolymers 95: 39–50, 2011.
Robust trypsin coating on electrospun polymer nanofibers in rigorous conditions and its uses for protein digestion
Authors: Ahn Hye‐Kyung , Kim Byoung Chan , Jun Seung‐Hyun , Chang Mun Seock , Lopez‐Ferrer Daniel , Smith Richard D. , Gu Man Bock , Lee Sang‐Won , Kim Beom Soo , Kim Jungbae 
Published: August 2010

AbstractAn efficient protein digestion in proteomic analysis requires the stabilization of proteases such as trypsin. In the present work, trypsin was stabilized in the form of enzyme coating on electrospun polymer nanofibers (EC‐TR), which crosslinks additional trypsin molecules onto covalently attached trypsin (CA‐TR). EC‐TR showed better stability than CA‐TR in rigorous conditions, such as at high temperatures of 40 and 50°C, in the presence of organic co‐solvents, and at various pH's. For example, the half‐lives of CA‐TR and EC‐TR were 1.42 and 231 h at 40°C, respectively. The improved stability of EC‐TR can be explained by covalent linkages on the surface of trypsin molecules, which effectively inhibits the denaturation, autolysis, and leaching of trypsin. The protein digestion was performed at 40°C by using both CA‐TR and EC‐TR in digesting a model protein, enolase. EC‐TR showed better performance and stability than CA‐TR by maintaining good performance of enolase digestion under recycled uses for a period of 1 week. In the same condition, CA‐TR showed poor performance from the beginning and could not be used for digestion at all after a few usages. The enzyme coating approach is anticipated to be successfully employed not only for protein digestion in proteomic analysis but also for various other fields where the poor enzyme stability presently hampers the practical applications of enzymes. Biotechnol. Bioeng. 2010;107: 917–923. © 2010 Wiley Periodicals, Inc.
ChemInform Abstract: Highly Ordered Polymer‐Inorganic Nanocomposites via Monomer Self‐ Assembly: In situ Condensation Approach.
Authors: GRAY D. H. , HU S. , JUANG E. , GIN D. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydriding Combustion Synthesis for the Production of Hydrogen Storage Alloy.
Authors: AKIYAMA T. , ISOGAI H. , YAGI J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1‐Styrylsilatrane.
Authors: STRADIOTTO M. , CROWE G. , RUFFOLO R. , BROOK M. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Elecrochemical and Spectroscopic Properties of a Series of tert‐Butyl‐ Substituted para‐Extended Quinones.
Authors: ZHOU J. , RIEKER A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Enantioselective Reduction with Novel, Bridged NADH Models.
Authors: KANOMATA N. , NAKATA T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Enantioselective Transfer of Chirality from a Less to a More Configurationally Unstable Stereogenic Center. A Practical Asymmetric Synthesis of (Fluoroalkyl)amines via Biomimetic Transamination.
Authors: SOLOSHONOK V. A. , ONO T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of Hydroxyiminoacetophenone with p‐Toluenesulfonyl Chloride and X‐Ray Diffraction Study of the Compound Obtained.
Authors: FEDOROV A. E. , NESTEROV V. N. , SHESTOPALOV A. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Synthesis of Biphenylacetic Acids via Pd/C‐Catalyzed Arylation.
Authors: GALA D. , STAMFORD A. , JENKINS J. , KUGELMAN M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Efficient Route to Imidazo(4,5‐c)pyrazol‐5‐ones.
Authors: VICENTINI C. B. , VERONESE A. C. , MANFRINI M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Cyclic Ether Compounds via Reductive Cleavage of Bicyclic Ketals.
Authors: JUN J.‐G. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Halosulfuron‐Methyl via Selective Chlorination at 3‐ and/ or 5‐Position of Pyrazole‐4‐carboxylates.
Authors: MORIMOTO K. , SATO T. , YAMAMOTO S. , TAKEUCHI H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile and Convenient Synthesis of 2,6‐Disubstituted 4H‐1,3‐Oxazin‐4‐ one Derivatives.
Authors: MORITA Y. , KANEKO M. , MATSUZAWA S. , YAMAMOTO Y. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Study on Azadirachtin. Part 2. Construction of the Decalin Moiety with Full Functionality on B‐Ring
Authors: WATANABE H. , WATANABE T. , MORI K. , KITAHARA T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carotenoid Glucoside Mycolic Acid Esters from the Nocardioform Actinomycetes, Rhodococcus rhodochrous.
Authors: TAKAICHI S. , TAMURA Y. , AZEGAMI K. , YAMAMOTO Y. , ISHIDSU J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies in Macrolide Synthesis: Stereocontrolled Synthesis of a C1‐C13 Segment of Concanamycin A.
Authors: PATERSON I. , MCLEOD M. D. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.