bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers to the Implementation of Infant- and Family-Centered Developmental Care From Focus Groups With Neonatal Care Providers
Authors: Detollenaere Jens , Benahmed Nadia , Costa Elena , Van den Heede Koen , Christiaens Wendy 
Published: May 2024

Aim:
Although infant- and family-centered developmental care (IFCDC) is scientifically grounded and offered in many hospitals to some extent, it has not yet been universally implemented as the standard of care. In this article, we aim to identify barriers to the implementation of IFCDC in Belgian neonatal care from the perspective of neonatal care providers.

Methods:
We conducted 8 online focus groups with 40 healthcare providers working in neonatal care services. An inductive thematic analysis was carried out by means of Nvivo.

Results:
The focus groups revealed barriers related to contextual, hospital, and neonatal unit characteristics. Barriers found in the hospital and neonatal unit were related to financing, staffing, infrastructure, access to knowledge/information and learning climate, leadership engagement, and relative priority of IFCDC. Contextual barriers were related to peer pressure and partnerships, newborn/parent needs and resources, external policy, and budgetary incentives.

Conclusion:
Three main barriers to IFCDC implementation have been identified. Resources (staffing, financing, and infrastructure) must be available and aligned with IFCDC standards, knowledge and information have to be accessible and continuously updated, and hospital management should support IFCDC implementation to create an enabling climate, including compatibility with the existing workflow, learning opportunities, and priority setting.
Investigation of the Effects of Thymoquinone and Dental Pulp-Derived Mesenchymal Stem Cells on Tibial Bone Defect Models
Authors: Ozden Ersin , Kaya Beyza , Guler Ridvan 
Published: May 2024

The thymoquinone obtained from Nigella sativa increases osteoblastic activity and significantly reduces the number of osteoclasts, thereby accelerating bone healing. In addition, mesenchymal stem cells isolated from various tissues are considered a potential cell source for bone regenerative therapies. The aim of this study is to investigate the effectiveness of thymoquinone, a current and novel agent, in combination with mesenchymal stem cells derived from the dental pulp in promoting bone healing. In the study, 28 male Sprague Dawley rats were used. The rats were divided into 4 groups, each consisting of 7 rats: the control group (group 1) (n=7), thymoquinone group (group 2) (n=7), stem cell group (group 3) (n=7), stem cell+thymoquinone group (group 4) (n=7). A bone defect of 4 mm in diameter and 5 mm in length was created in the left tibial bones of all rats with a trephine bur. In group 1, no procedure was applied to the defect area. Group 2 was applied thymoquinone (10 mg/kg) with oral gavage. In group 3, stem cells were used locally to the defect area. In group 4, stem cells and thymoquinone (10 mg/kg) was applied to the defect area. All rats were killed on the 28th day of the experiment. Tibia tissues extracted during sacrifice were histomorphologically examined in a fixative solution. Significant differences were found in terms of new bone formation and osteoblastic activity values in the “thymoquinone” (P<0.05), “stem cell” (P<0.05), and “stem cell+thymoquinone” (P<0.05) groups compared to the “control” group. In addition, while there was no significant difference in the “thymoquinone” group compared to these stem cell+thymoquinone group in terms of osteoblastic activity (P>0.05), the difference in terms of new bone formation was found to be significantly lower. No significant differences among the other groups were observed in new bone formation and osteoblastic activity (P>0.05). According to the results of our study, stem cell+thymoquinone treatment for bone defects is not only more effective than thymoquinone or stem cell treatment alone but also induces greater development of bone trabeculae, contributes to the matrix and connective tissue formation, and increases the number of osteoblasts and osteocytes involved in bone formation.
Full-left/Full-right Liver Splitting With Middle Hepatic Vein and Caval Partition During Dual Hypothermic Oxygenated Machine Perfusion
Authors: Cillo Umberto , Lauterio Andrea , Furlanetto Alessandro , Canitano Nicola , Polacco Marina , Buscemi Vincenzo , De Carlis Riccardo , Boetto Riccardo , D’Amico Francesco Enrico , Bassi Domenico , De Carlis Luciano , Gringeri Enrico 
Published: May 2024

Background.
Split liver transplantation is a valuable means of mitigating organ scarcity but requires significant surgical and logistical effort. Ex vivo splitting is associated with prolonged cold ischemia, with potentially negative effects on organ viability. Machine perfusion can mitigate the effects of ischemia–reperfusion injury by restoring cellular energy and improving outcomes.

Methods.
We describe a novel technique of full-left/full-right liver splitting, with splitting and reconstruction of the vena cava and middle hepatic vein, with dual arterial and portal hypothermic oxygenated machine perfusion. The accompanying video depicts the main surgical passages, notably the splitting of the vena cava and middle hepatic vein, the parenchymal transection, and the venous reconstruction.

Results.
The left graft was allocated to a pediatric patient having methylmalonic aciduria, whereas the right graft was allocated to an adult patient affected by hepatocellular carcinoma and cirrhosis.

Conclusions.
This technique allows ex situ splitting, counterbalancing prolonged ischemia with the positive effects of hypothermic oxygenated machine perfusion on graft viability. The venous outflow is preserved, safeguarding both grafts from venous congestion; all reconstructions can be performed ex situ, minimizing warm ischemia. Moreover, there is no need for highly skilled surgeons to reach the donor hospital, thereby simplifying logistical aspects.
A Delphi Approach to Define Lucid Episodes in People Living With Dementia
Authors: Bangerter Lauren R. , Griffin Joan M. , Kim Kyungmin , Finnie Dawn M. , Lapid Maria I. , Gaugler Joseph E. , Biggar Virginia S. , Frangiosa Theresa 
Published: May 2024

Purpose:
Lucid episodes (LEs: unexpected episodes of spontaneous, meaningful, and relevant communication or behavior) in Alzheimer disease and related dementias are a new area of scientific inquiry that lacks clinical consensus and require more conceptual attention.

Methods:
We aimed to measure consensus from an expert group on: (1) potential medical or clinical explanations for LEs; (2) necessary medical and clinical context to LEs; and (3) interpretation of LEs.

Patients:
We convened 13 experts from different disciplines (neurology, psychiatry, psychology, pharmacy, palliative care, hospice, nursing, social work, primary care, geriatrics, and professional home caregivers) to identify elements of LEs.

Results:
Experts provided a range of opinions on medical and clinical explanations and questions to understand LEs. Consensus on LEs when presented with clinical vignettes was not reached. Panelists highlighted key medical and contextual factors needed to make a definitive judgement about LEs.

Conclusion:
There is variability in how LEs are interpreted by clinical experts, which complicates the identification of LEs in Alzheimer disease and related dementias.
Diverging Arabidopsis populations quickly accumulate pollen-acting genetic incompatibilities
Authors: Condon Chris , Carpentier Fantin , Tabourin Marie , Wozniak Natalia , Takou Margarita , Blassiau Christelle , Kumar Vinod , Pietzenuk Björn , Habert Rémi , Meaux Juliette De , Krämer Ute , Roux Camille , Corbett-Detig Russell , Castric Vincent 
Published: May 2024

AbstractThe process by which species diverge from one another, gradually accumulate genetic incompatibilities and eventually reach full-fledged reproductive isolation is a key question in evolutionary biology. However, the nature of reproductive barriers, the pace at which they accumulate and their genomic distribution remain poorly documented. The disruption of co-adapted epistatic interactions in hybrids and the accumulation of selfish genetic elements are proposed contributors to this process, and can lead to the distortion of the mendelian segregation of the affected loci across the genome. In this study we detect and quantify segregation distortion across the genomes of crosses produced from a diverse sampling ofArabidopsis lyrataandA. halleripopulations, two species at the early stages of speciation and that can still interbreed. We show that both the frequency of occurrence and the magnitude of distortion loci increase as the parents’ genetic distance from one another increases. We also observe that distorter loci evolve rapidly, as they occur not only within interspecific hybrids, but also in intraspecific hybrids produced from isolated population crosses. Finally, we identify both genome-wide non-independence and two specific genomic regions on different chromosomes where opposite distortion effects are repeatedly observed across multiple F1 individuals, suggesting negative epistasis is a major contributor to the evolution of hybrid segregation distortion. Our study demonstrates that pollen-acting segregation distortion is ubiquitous, and contributes not only to the ongoing reproductive isolation betweenA. halleriandA. lyrata, but also between very recently diverged populations of the same species.
Developing a User-Friendly Oropharyngeal HPV-16 Point-of-Care Diagnostic: HPV-16 Virus Detection in Oral Rinse Sample Matrix With Colorimetric Loop-Mediated Isothermal Amplification
Authors: Halphen John , Wright Nicholas A. , Fisher Samantha , Juarez San Juana I. , Sanchez Lisa , Riedel Timothy E. 
Published: May 2024

AbstractHuman papillomavirus type 16 (HPV-16) is a highly carcinogenic variant that is responsible for the majority of human oropharyngeal cancers. HPV-16 is critically under-tested, and there are currently no commercially available HPV-16 diagnostics for oral infection sites. We developed an oral HPV-16 diagnostic system with the goal of being as user-friendly and non-invasive as possible. The system tests an oral rinse sample from the patient, is interpreted via a color change from pink to yellow, and can be incubated in a battery-powered coffee mug. The colorimetric loop-mediated isothermal amplification-based diagnostic is sensitive to synthetic HPV-16 E7/E1 DNA at levels as low as 103copies after 20 minutes of incubation. This study supports the potential to develop an easy-to-assemble and easy-to-use diagnostic for oropharyngeal HPV-16 infections.
Neuronal phenotype defined by transcriptome-wide bursting kinetics in pyramidal and fast-spiking cells
Authors: Tukacs Vanda , Fladhus Eva Kristine , Mittli Dániel , Lőrincz Magor L. , Eberwine James , Kékesi Katalin Adrienna , Juhász Gábor 
Published: May 2024

ABSTRACTSingle-cell sequencing revealed the transcriptional heterogeneity of neurons and introduced transcriptome-defined neuron types and subtypes. Temporal recordings of gene transcription showed that mRNA synthesis is arranged into transcriptional bursts which can be characterized by kinetic parameters. Here, we selected two distinct, functionally homogenous, and electrophysiologically well-defined neuronal cell types – the pyramidal cells and fast-spiking interneurons – for transcriptional burst analysis. Hierarchical clustering based on electrophysiological parameters recovered these cell types. In contrast, clustering based on transcripts failed to differentiate these neuronal phenotypes. We applied mathematical models to analyze burst kinetics of fast-spiking and pyramidal cells to explore the transcriptional underpinning of their distinct physiological functions. We found that inferred burst kinetic parameters are distinct measures of gene expression from average mRNA counts. Based on our results, we suggest that burst kinetics can be considered as a component of transcriptome-defined neuronal phenotype besides mRNA counts.
Visual network modularity and communication alterations in ADHD subtypes: evidence from source localized EEG and graph theoretical analysis
Authors: Ghaderi Amir Hossein , Taghizadeh Shiva , Nazari Mohammad Ali 
Published: May 2024

AbstractThe neurobiological basis of ADHD and its subtypes remains unclear, with inconsistent findings from studies using electrophysiology and neuroimaging. Some studies suggest ADHD-I is a distinct disorder, but there is also evidence of similar neural basis in ADHD-I and ADHD-C subtypes. This study investigates the neural basis of ADHD and its subtypes using a subnetwork modularity approach based on graph theoretical analysis of EEG data from 35 children aged 7-11. EEG was recorded in the eyes open condition and preprocessed. After preprocessing, data was analyzed using LORETA algorithm to estimate current densities in 84 regions of interest (ROIs) in the cortex and calculate functional connectivity between these ROIs in different EEG frequency bands. Then, we evaluated modularity of five functional brain networks (default mode, central control, salience, visual, and sensorimotor) using Newman modularity algorithm. Further, we evaluated edge betweenness centrality to assess communications between these functional brain networks. The study found that different brain networks have modularity in certain frequency bands, and ADHD groups showed reduced modularity of the visual network compared to normal groups in the alpha1 band (8-10 Hz). The communication between the visual network and other brain networks, except the salience network, was also reduced in ADHD groups (in the alpha1 band). However, there were no significant differences in the modularity of brain networks and communication among them between two ADHD subtypes. The results suggest a novel mechanism for ADHD involving lower intrinsic modularity in the visual network, disturbed communication between the visual network and other networks, and potential impact on the function of control and sensorimotor networks. Further, our results suggest that there may be a common neural basis for both subtypes, involving a shared disturbance in the modularity and connectivity of the ventral network. This supports the idea that ADHD-I and ADHD-C are subtypes within the same category and contradicts previous studies that suggest they are separate disorders.
Modeling college faculty users’ potential acceptance of library data services for research and teaching
Authors: Xu Qiong 
Published: May 2024

Purpose
The increasingly active data practice in academic environments makes investigating college faculty users’ potential needs for library data services (LDS) essential. Guided by a conceptual framework rooted in the data lifecycle and the extended technology acceptance model, this study aims to investigate the relationship between faculty’s data engagement (DE) and their attitudes toward multiaspect LDS.

Design/methodology/approach
An online survey at a master’s college was conducted to collect data regarding faculty data practice, potential needs for data services (DS) and attitudes toward multiaspect LDS. Based on 139 complete and valid responses, the study built three conceptual models to demonstrate faculty users’ potential acceptance of LDS for research and teaching.

Findings
Participants’ research and teaching-related DE and background factors directly or indirectly affect their attitudes toward general DS, an institutional data repository if available and repository-based data curation.

Originality/value
The study contributes to DS and librarianship research by offering three conceptual models to explore LDS’ holistic support for faculty research and teaching. Moreover, the study provides insights into faculty’s job-related DE factors and calls for future research on effective DS in more college communities.
I need you to survive: a qualitative exploration of family-based beliefs among resettled Congolese refugee women in the USA
Authors: Spates Kamesha , Evans Na’Tasha , Smith Jordan , Gairola Richa , Jindra Rebecca , Guttoo Parishma , Mubikayi Kabasele Cedric , Kirkland Chelsey , Aminu PraiseGod 
Published: May 2024

Purpose
The prevalence of Congolese refugee women seeking asylum in the USA has recently garnered substantial attention. Many women have fled the Democratic Republic of Congo due to trauma and loss. Likewise, the resettlement process, particularly acculturative stress, may exacerbate mental health issues such as depression and anxiety. By recognizing the centrality of family within Congolese culture, this study aims to investigate cultural beliefs about family among Congolese refugee women in the USA, using acculturative theory as an interpretative lens.

Design/methodology/approach
The authors’ study centered on understanding the resettlement experiences of 20 Congolese refugee women living within an urban area of Midwest America after their arrival in America since 2011. Through using convenient sampling methods, the authors chose these particular activists as they could provide insight into their stories concerning their journey from Congo to settling down as refugees within Northeast America. During interviews, semi-structured questioning was used to gather responses from participants which were later analyzed through implementing a thematic interpretation process.

Findings
Three themes emerged encapsulating cultural beliefs about family: supporting one another; the importance of togetherness; and disciplining our children. These findings provide culturally tailored resources to support Congolese refugee women and their families upon resettlement optimally.

Research limitations/implications
The authors’ work provides health equity researchers with an opportunity to better understand cultural beliefs among Congolese refugee women. Findings from this study provide an increased understanding of how to provide culturally specific tools to better aid Congolese refugee women and their families upon arrival.

Practical implications
The authors’ research offers insights for health equity researchers seeking to understand the cultural beliefs of Congolese refugee women. The findings contribute to an enhanced understanding of how to provide culturally specific resources better to support Congolese refugee women and their families upon arrival.

Originality/value
The authors verify that, to the best of the authors’ knowledge, the paper was written completely independently, and neither the entire work nor any of its parts have been previously published. The authors confirm that the paper has not been submitted to peer review, nor is in the process of peer reviewing, nor has been accepted for publishing in another journal. The authors confirm that the research in their work is original.
Teacher’s agency in education for sustainable development: an East-West collaborative Erasmus programme using Q methodology
Authors: Guerra Aida , Chen Juebei , Du Xiangyun , Nielsen Helle , Kørnøv Lone 
Published: May 2024

Purpose
The integration of ESD is a complex problem. It calls for an innovative, student-centred curriculum, as well as professional learning and agency, by which university teachers feel empowered to change their practice and direct their peers and institutions towards ESD. This study aims to explore what university teachers consider to be the most important attitudes in supporting their agency to deliver Education for Sustainable Development (ESD) via a Problem Based Learning (PBL) programme.

Design/methodology/approach
This study presents a theoretical framework for professional agency comprising three domains: intrapersonal, action and environmental. A Q methodology is adopted to explore university teachers’ perceptions of the most important environmental factors in supporting their ability to deliver ESD via a problem-based learning (PBL) programme. Twenty-eight participants from six Southeast Asian universities took part in a PBL-based professional development programme designed to improve teachers’ ESD- and PBL-based skills and competencies.

Findings
The results indicate that the participants were confident in their ability to implement PBL and saw PBL as an approach suitable for addressing current educational, professional and societal challenges. This study offers a series of recommendations to help university teachers develop their ESD and PBL practices.

Originality/value
Although the literature on human agency is extensive, research surrounding teachers’ professional agency in the context of ESD and PBL in higher education is lacking. The present study addresses this gap by capturing individual teachers’ beliefs, perceptions and views and by using Q methodology to examine the subjectivity of study participants.
Exploring the impact of athlete brand image on fans’ behavioural outcomes: the role of emotional attachment and perceived price value
Authors: Zheng Longzhao , Xu Ying 
Published: May 2024

PurposeThis study aims to explore the impact of athlete brand image on fans’ social media engagement, purchase intentions, and also examines the mediating role of emotional attachment on these relationships, as well as the moderating role of perceived price value between emotional attachment and purchase intentions.Design/methodology/approachThe data are based on an online survey conducted in China (N = 572). The PLS-SEM (partial least squares structural equation model) and regression-based estimation method (PROCESS) are employed to test the hypotheses.FindingsThe results indicate a positive relationship between athletes’ athletic performance and fans’ social media engagement as well as purchase intentions. The impact of athletes’ attractive appearance and marketable lifestyle on fans’ purchase intentions is sequentially mediated by emotional attachment and social media engagement. Moreover, the mediation effect of athletes’ off-field image and purchase intentions is contingent upon fans’ perceived price value.Research limitations/implicationsAthletes and marketers could integrate and leverage both the on-field and off-field attributes to cultivate emotional connections with fans. Sports organizations and managers need to pay attention to fans’ social media engagement and provide content that increases engagement and converts into transactional behavioural intentions.Originality/valueThe study provides empirical evidence of the mediating role of emotional attachment between athlete brand image and fans’ purchase intentions. The explanatory mechanisms involving emotional attachment and social media engagement (non-transactional behavioural intentions) are anticipated to be a noteworthy addition to the traditional fan transactional behavioural intentions framework. Moreover, the research introduces and confirms perceived price value as a crucial moderating factor influencing the relationship between emotional attachment and purchase intentions.