bluuebunny/crossref_metadata_2025_split huggingface dataset:
Generic low-atmosphere signatures of swirled-anemone jets
Authors: Joshi Reetika , Aulanier Guillaume , Radcliffe Alice , Rouppe van der Voort Luc , Pariat Etienne , Nóbrega-Siverio Daniel , Schmieder Brigitte 
Published: May 2024

Context.Solar jets are collimated plasma flows moving along magnetic field lines and are accelerated at low altitude following magnetic reconnection. Several of them originate from anemone-shaped low-lying arcades, and the most impulsive ones tend to be relatively wider and display untwisting motions.Aims.We aim to establish typical behaviours and observational signatures in the low atmosphere that can occur in response to the coronal development of such impulsive jets.Methods.We analysed an observed solar jet associated with a circular flare ribbon using high-resolution observations from SST coordinated with IRIS and SDO. We related specifically identified features with those developing in a generic 3D line-tied numerical simulation of reconnection-driven jets performed with the ARMS code.Results.We identified three features in the SST observations: the formation of a hook along the circular ribbon, the gradual widening of the jet through the apparent displacement of its kinked edge towards (and not away) from the presumed reconnection site, and the falling back of some of the jet plasma towards a footpoint offset from that of the jet itself. The 3D numerical simulation naturally accounts for these features, which were not imposed a priori. Our analyses allowed us to interpret them in the context of the 3D geometry of the asymmetric swirled-anemone loops and their sequences of reconnection with ambient coronal loops.Conclusions.Given the relatively simple conditions in which the observed jet occurred, together with the generic nature of the simulation that comprised minimum assumptions, we predict that the specific features that we identified and interpreted are probably typical of every impulsive jet.
Update Kontraindikationen Peritonealdialyse
Authors: Artunc Ferruh 
Published: May 2024

ZUSAMMENFASSUNGDie Peritonealdialyse (PD) ist eine Form der Nierenersatztherapie, die den betroffenen Patienten eine selbstständige Behandlung im heimischen Umfeld ermöglicht. Trotz guter Ergebnisse ist die PD im Vergleich zur Hämodialyse (HD) weltweit unterrepräsentiert. Einer der Gründe ist, dass in vielen Fällen medizinische Kontraindikationen angeführt werden. Die einzige absolute Kontraindikation für eine PD ist die Unmöglichkeit eines peritonealen Stoffaustauschs durch aktive Prozesse in der Bauchhöhle, eine verringerte Oberfläche oder eine peritoneale Fibrose. Sämtliche weitere Kontraindikationen wie Adhäsionen, Anurie, Adipositas, ungeplanter Start oder Leckagen sind relativ und können potenziell überwunden werden. Dazu ist jedoch die Expertise eines erfahrenen und gut aufgestellten PD-Zentrums erforderlich.
Peritonealdialyse assoziierte Peritonitis
Authors: Kimmel Martin 
Published: May 2024

ZUSAMMENFASSUNGIm Verlauf einer Peritonealdialyse (PD) können infektiöse Komplikationen auftreten, zu denen PD-Katheter assoziierte Infektionen und die PD-assoziierte Peritonitis gezählt werden. In den aktualisierten internationalen Leitlinien der International Society of Peritoneal Dialysis (ISPD) zur PD-assoziierten Peritonitis und zu PD-Katheter assoziierten Infektionen sind alle wichtigen Aspekte in übersichtlichen Algorithmen umfangreich dargestellt. In diesem Beitrag werden einige Aspekte des Managements der PD-assoziierten Peritonitis bezüglich der Prävention, der Präsentation und Diagnosestellung, des praktischen empirischen Vorgehens und der gezielten Antibiotikatherapie zusammengefasst.
Biologika in der dermatologischen Praxis – eine 20-jährige Geschichte
Authors: Jahn Sigbert , Diamanti Evangelia , Wagner Christine , Prestel Julia , Herbst Matthias 
Published: May 2024

ZusammenfassungImmuntherapien mit Biologika (monoklonalen Antikörpern, Fusionsproteinen) haben das dermatologische therapeutische Arsenal in den letzten 20 Jahren enorm erweitert und die Therapie mittelschwerer bis schwerer entzündlicher Dermatosen deutlich effizienter gemacht. Dieses Jubiläum hat uns motiviert, einen Rückblick zu halten auf die Entwicklung der Biologikatherapien in der Dermatologie und diesen mit eigenen Erfahrungen aus der dermatologischen Praxis zu illustrieren.
Effects of Hyperglycemia on Angiogenesis in Human Placental
Endothelial Cells
Authors: Yanik Turkan , Katirci Ertan , Simsek Mehmet , Korgun Emin Turkay , Kipmen-Korgun Dijle 
Published: May 2024

AbstractThe placenta is a temporary organ that provides communication between the mother
and fetus. Maternal diabetes and abnormal placental angiogenesis may be linked.
We investigated the angiogenesis mechanism resulting from VEGF and glucose
stimulation in PECs obtained from human term placenta. Immunohistochemistry was
performed to characterize PECs obtained from human term placenta. D-glucose was
added to the medium containing PECs to establish normoglycemic and hyperglycemic
conditions. The expression levels of VEGF, VEGFR-1 and VEGFR-2 genes and
proteins in PECs from the control and experimental groups were analyzed by
RT-PCR and Western blotting, respectively. With 48-hours incubation, gene
expressions increased due to hyperglycemia, while protein levels increased due
to the combined effect of VEGF and hyperglycemia. While VEGFR-2 gene expression
and protein amounts increased in 24-hours due to the combined effect of VEGF and
hyperglycemia, the effect of VEGF stimulation and glucose level on VEGFR-2
decreased in 48-hour incubation with time. VEGF, VEGFR-1 and VEGFR-2 genes and
proteins were affected by hyperglycemic conditions in PECs. Hyperglycemia
occurring in various conditions such as gestational diabetes mellitus and
diabetes mellitus may affect VEGF, VEGFR-1 and VEGFR-2 genes and proteins of
PECs derived from human term placenta.
Nephrotisches Syndrom nach Infektion eines ventrikuloatrialen Shunts
Authors: Schmorl Philipp , Deicher Robert , Bräsen Jan Hinrich , Martin Stephan 
Published: May 2024

ZUSAMMENFASSUNGEin männlicher Patient (Mitte/Ende 20 Jahre alt) stellte sich in der Urologie des MZEB mit seit einem Monat blutig tingiertem, zunehmend trübem Urin ohne Dysurie oder Harninkontinenz vor. Mit dem klinischen Bild eines nephrotischen Syndroms erfolgte eine notfallmäßige Krankenhauseinweisung in die medizinische Klinik. Nach umfangreicher internistischer Diagnostik wurde eine Glomerulonephritis festgestellt, welche durch eine Shuntinfektion bedingt war. Nach entsprechender Therapie konnte der Patient in deutlich verbessertem Zustand entlassen werden. Im vorliegenden Fall lässt sich die ungewöhnliche Symptomatik von ursächlichen Problemen insbesondere vor dem Hintergrund schwerer Behinderungen darstellen.
The beauty of pediatric musculoskeletal ultrasound
Authors: Drakonaki Elena E , Adriaensen Miraude , Simoni Paolo , Aparisi Gomez Maria Pilar 
Published: May 2024

AbstractUltrasound is a powerful technique in pediatric imaging and musculoskeletal (MSK) imaging in many specific clinical scenarios. This article will feature some common and less common spot diagnoses in pediatric musculoskeletal ultrasound.Cases were collected by members of the Educational Committee of the ESSR (European Society of musculoSkeletal Radiology) and the Pediatric Subcommittee of the ESSR with expertise in musculoskeletal ultrasound.Fifteen clinical entities are discussed based on the features that allow diagnosis by ultrasound.Clinical history, location, and ultrasound appearance are the keys to spot diagnoses when performing pediatric musculoskeletal ultrasound.
BF3·OEt2-Mediated (3+2) Cycloaddition Reactions of Donor-Acceptor Cyclopropanes (DACs) with Cyanamides: Access to Cyclic Amidines
Authors: Goswami Avijit , Gopal Braj , Singh Prasoon Raj , Bhatt Shubham 
Published: May 2024

AbstractA BF3·OEt2-promoted facile synthesis of cyclic amidines (2-amino-1-pyrrolines) has been developed via the (3+2)-cycloaddition of cyanamides with donor-acceptor cyclopropanes (DACs). In addition to this, the protocol has been successfully extended to construct a dimerized amidine derivative and gram-scale synthesis with great efficiency.
Skeletal Effects of a Prolonged Oral Metformin Treatment in Adult
Wistar Rats
Authors: Wanionok Nahuel E. , Molinuevo María S. , Fernández Juan M. , Lucas Besada , Cortizo Ana M. , Castillo Evelyn J. , Jiron Jessica M. , Claudia Sedlinsky , Leon Schurman , Aguirre José I. , McCarthy Antonio D. 
Published: May 2024

Abstract
Introduction We previously showed that a 3-week oral metformin (MET)
treatment enhances the osteogenic potential of bone marrow stromal cells (BMSCs)
and improves several bone histomorphometric parameters in Wistar rats with
metabolic syndrome (MetS). However, the skeletal effects of extended periods of
MET need to be completely elucidated. Hence, in this study, the impact of a
prolonged (3-month) MET treatment was investigated on bone architecture,
histomorphometric and biomechanics variables, and osteogenic potential of BMSCs
in Wistar rats with or without MetS.
Materials and Methods Young male Wistar rats (n=36) were randomized into
four groups (n=9) that received either 20% fructose (F), MET
(MET), F plus MET treatments (FMET), or drinking water
alone (Veh). Rats were euthanized, blood was collected, and bones were
dissected and processed for peripheral quantitative computed tomography (pQCT)
analysis, static and dynamic histomorphometry, and bone biomechanics. In
addition, BMSCs were isolated to determine their osteogenic potential.
Results MET affected trabecular and cortical bone, altering bone
architecture and biomechanics. Furthermore, MET increased the pro-resorptive
profile of BMSCs. In addition, fructose-induced MetS practically did not affect
the the structural or mechanical variables of the skeleton.
Conclusion A 3-month treatment with MET (with or without MetS) affects
bone architecture and biomechanical variables in Wistar rats.
Novel Eyelid Supraorbital Pretemporal Approach to the Anterior Communicating Artery Complex: A Quantitative Cadaveric Comparative Study
Authors: Zhao Xiaochun , Evans Alexander R. , Shi Helen H. , Pelargos Panayiotis E. , Tan Jeremy , Do Thai , Dunn Ian F. , Graffeo Christopher , Bauer Andrew M. 
Published: May 2024

Abstract
Objectives Access to the anterior communicating artery (ACom) complex may be achieved via the modified orbito-zygomatic (mOZ) or eyelid supraorbital (ES) approaches. Further, the ES approach may improve cosmesis at the cost of decreased exposure and maneuverability. Thus, a novel eyelid supraorbital pretemporal (ESP) approach, a combination of the ES approach with a pretemporal dissection, may optimize the shortcomings of the ES approach.
Design This is a cadaveric study.
Setting Five ES, ESP, and mOZ approaches were performed on cadaveric heads and compared.
Participants Cadaveric specimens were provided under the University of Oklahoma Health Science Center's Willed Body Program.
Main Outcome Measures Quantitative measures of exposure, maneuverability, and angles of attack in horizontal and vertical planes were compared between approaches.
Results The ESP approach was superior in terms of exposure and deep maneuverability when compared with the ES approach (p < 0.01). In addition, this approach demonstrated superior angles of attack in vertical (p < 0.01) and horizontal (p = 0.045) planes. When compared with the mOZ approach, the ESP approach provided significantly greater exposure to the contralateral A2 (p < 0.01) with a less favorable horizontal angle of attack (p < 0.01). The ESP provides exact exposure to complete the pretemporal osteotomy, offering a unique perspective on the ACom complex.
Conclusion When accessing the ACom complex, the ESP approach yields superior exposure and maneuverability compared with the ES approach and is comparable to the mOZ approach, with unique advantages provided by the addition of pretemporal osteotomy and dissection.
Use of Jugular Venous Pressure to Optimize Outcomes of Vestibular Schwannoma Resection: A Review of the Literature and Proof of Concept
Authors: Brakel Benjamin , Wang Jessica , Kam Jeremy , Huttunen Henrik , Dhaliwal Bali , McEwen Jon , Westerberg Brian , Makarenko Serge , Akagami Ryojo 
Published: May 2024

Abstract
Background Surgical resection of vestibular schwannoma (VS) and other benign posterior fossa tumors is often curative if gross total resection is achieved; however, these lesions pose unique challenges due to their intricate location and proximity to critical structures. Approaches for resection often utilize lateral head rotation and neck flexion to optimize the surgical field. However, this may inadvertently occlude cerebral venous drainage, elevating intracranial pressure (ICP) and increasing intraoperative bleeding, potentially increasing the operative risk to patients.
Methods We review relevant literature regarding the effects of head rotation and neck flexion on internal jugular vein (IJV) occlusion and ICP and highlight the notion that head rotation and flexion may occlude the ipsilateral IJV, increasing ICP. Subsequently, we propose a novel technique using continuous, real-time monitoring of jugular bulb pressure (JBP) to detect obstructions in jugular venous flow and guide optimal head positioning prior to VS resection.
Results As proof of concept, we present a single-patient case in which JBP monitoring was employed to optimize head positioning prior to a VS resection, which shows a significant reduction in JBP compared with traditional positioning.
Conclusion This innovative approach offers promise in enhancing the safety and efficacy of intracranial surgery for VS and other neurosurgical procedures.
Primary Extraskeletal Falcine Myxoid Chondrosarcoma—A Case Report and Review of Literature
Authors: Narayanan Rajasekhar , Venugopal Renjith T. , L. Suresh Kumar K. , B. Jose P. , Bahuleyan Anjana , P. Reshmi C. , Varghese Thomas , Pillai Marthanda A. 
Published: May 2024

AbstractIntracranial chondrosarcomas are rare malignant lesions. Both skull base and dural-based extraosseous chondrosarcomas have been reported to occur intracranially. Dural-based chondrosarcomas arising from the falx cerebri are rare lesions with only 19 cases reported till date. Although conventional, mesenchymal, and myxoid variants of chondrosarcomas have been reported intracranially, myxoid variant are the rarest with only 17 cases reported till date, among which only 2 were falcine. We are reporting the third case of falcine myxoid chondrosarcoma in a 32-year-old man who presented with seizures and subtle lower limb weakness. Radiological findings were suggestive of an atypical meningioma in the falcine region. Macroscopically total resection of the tumor was done. Histopathological examination confirmed myxoid chondrosarcoma, grade 1. Postoperative period was uneventful, and the patient remains asymptomatic 34 months after the surgery without the application of any adjuvant therapy. Falcine myxoid chondrosarcomas are extremely rare lesions with variable aggressiveness as suggested by the three cases reported till now including the present case.
The Ability to Detect the COVID-19 Genome Using Saliva Swabs in Comparison with Nasopharyngeal Swabs in Baghdad
Authors: Alkaisi Amera Khalil , Abdulateef Yasir Mufeed , Abdo Salma Burhan 
Published: May 2024

Abstract
Objective Nasopharyngeal swab (NPS) sampling has been recommended by the World Health Organization (WHO) since the start of the COVID-19 pandemic, and real-time reverse transcription polymerase chain reaction (RT–PCR) is used to detect SARS-CoV- 2, the causative agent of COVID-19. This sampling technique is invasive and causes discomfort to the patient. Saliva swabs (SSs) can be used as an alternative noninvasive method; however, there are limited data confirming its suitability for the diagnosis of COVID-19. The aim of this study was to test the ability to detect COVID-19 using SSs in comparison with NPSs in the Baghdad Alkark sector.
Materials and Methods Six hundred and fifty patients were included in this study, and written informed consent was obtained from all the study participants. Paired NPSs and SSs were collected at the same time from each participant between days 3 and 5 after disease initiation. SSs were taken from the sublingual area. An RT‒PCR assay was used to detect the viral ribonucleic acid (RNA) of SARS-CoV-2 for the diagnosis of COVID-19. The chi-squared test was used for data analysis, with p < 0.05 considered significant.
Results Out of 650 participants with suspected COVID-19 (313 males and 145 females), 313 were confirmed to be positive for COVID-19 by quantitative RT–PCR (RT‒qPCR) using both samples. The ages ranged between 12 and 85 years, with a mean/standard deviation (SD) of 45.45 (16.62) years. All the cases with positive results using NPSs were also positive when SSs were used. Statistically, there was no significant difference between the two groups (p = 0.347).
Conclusion RT‒PCR assays conducted on SSs and NPSs performed similarly, indicating that SSs may be a safe, inexpensive diagnostic sampling method and an effective tool for population screening. We recommend more studies to support this finding.
A Cross-Sectional Study on Incidence and Predictors of Self-Reported Dental Anxiety among Nigerian Public Primary Schoolchildren
Authors: Eseadi Chiedu , Surjaningrum Endang R. 
Published: May 2024

Abstract
Objective The presence of dental anxiety in Nigerian public primary schools may be one of the main obstacles preventing schoolchildren from effectively utilizing dental care services. The main objective of this cross-sectional study was to investigate the incidence and factors associated with self-reported dental anxiety among Nigerian public primary school children.
Materials and Methods A cross-sectional, observational design was employed to examine 434 primary schoolchildren (aged 6–9 years) from selected schools in Abia State, Southeastern Nigeria. Data collection was conducted using the Modified Dental Anxiety Scale, which includes 5-point Likert responses, five questions, and demonstrates good internal consistency.
Results The findings indicate that there was no statistically significant difference in the occurrence of dental anxiety between male and female schoolchildren (p = 0.374). In total, 1.9, 8.7, 10.1, 36.4, and 42.9% of the schoolchildren reported experiencing no dental anxiety, mild, moderate, extreme, and severe levels of dental anxiety, respectively. Furthermore, the results reveal that 2.1% of the variance in children's dental anxiety scores could be accounted for by factors such as gender, age, socioeconomic status, and parental education. However, the influence of gender (B = 0.183; p = 0.060; 95% confidence interval [CI]: –0.008 to 0.374), age (B = –0.128; p = 0.187; 95% CI: –0.318 to 0.062), socioeconomic status (B = –0.067; p = 0.124; 95% CI: –0.152 to 0.018), and parental education (B = –0.045; p = 0.420; 95% CI: –0.154 to 0.064) on schoolchildren's dental anxiety was not significant.Male and female schoolchildren did not have significantly different dental anxiety levels. Gender, age, socioeconomic status, or parent education level did not significantly predict the dental anxiety among schoolchildren.
Conclusion School-based interventions need to be targeted to reduce dental anxiety among male and female primary schoolchildren in the study area. Clinicians should consider providing interventions to manage dental anxiety in children with moderate to severe levels of anxiety.
Sleep Hygiene Intervention Improves Sleep Time and Duration in High School Students
Authors: Corrêa Camila de Castro , Silva Gabryella Nery Teles Nogueira , Viana Giovanna Régis , Lira Amanda Lima e , Macedo Gabriela Duarte , Weber Silke Anna Theresa 
Published: May 2024

Abstract
Objective To evaluate the effects of a sleep hygiene education program for adolescents to address excessive daytime sleepiness, insomnia, and sleep-related behaviors.
Materials and Methods The participants were 98 high school students from the 11th and 12th grades. A day-long health promotion action was conducted at their school science fair to disseminate relevant information about sleep disorders. Social status and sleep perception and habits were evaluated through the following validated questionnaires: the Brazilian Economic Classification Criteria, a questionnaire on sleep habits for adolescents, the Pediatric Daytime Sleepiness Scale, the Insomnia Severity Index, and the Sleep Time-Related Information and Communication Technology questionnaire. The questionnaires were administered before the fair and 12 months after participation, and the results before and after the intervention were compared by means of the Student t-test and the Fisher exact test. For the correlations involving the results, the Pearson correlation was used with the level of significance of p < 0.05.
Results A qualitative reduction in poor bedtime habits was observed after the intervention, such as watching television and leaving a cell phone on with sound. A higher frequency of use of electronic devices can affect school performance and contribute to later bedtime on weekends (p < 0.001). Excessive daytime sleepiness was correlated with the excessive use of electronic devices (p = 0.017).
Conclusion Some habits changed after the awareness intervention. There was an impact of the use of electronic devices on academic performance, on the regularity of bedtimes, and on excessive daytime sleepiness. We emphasize the importance of health education programs with sustainable actions following actual changes in behavior.
Bruxism, Lifestyle, Anxiety, and Sleep Impairment in Dental Students
Authors: Hilgenberg-Sydney Priscila Brenner , Necker Amanda , Kajevski Luiz Felipe , Senff Jordana , Bertoli Fernanda Mara de Paiva , de Souza Juliana Feltrin 
Published: May 2024

AbstractThe aim of this study was to verify the correlation of self-reported sleep and awake bruxism with demographic characteristics, oral behaviors, anxiety, temporomandibular disorder (TMD) signs and symptoms, sleep quality, and orthodontic treatment history in dental students. A total of 104 students of Dentistry located in Paraná (South Brazilian State) answered the following self-administered questionnaires: Oral Behavior Checklist, State Anxiety Inventory, TMD signs and symptoms questionnaire, and the Pittsburgh Sleep Quality Index. Associations between possible awake bruxism (AB) and sleep bruxism (SB) with sleep quality, anxiety, and TMD were analyzed by Poisson Regression with robust variance. The significance level adopted was 5%. The frequency of AB and SB was 76% and 55.8%, respectively. A statistically higher frequency of AB was observed in students who had the following conditions: use of psychotropic medication, physical activity practitioners, moderate or high level of anxiety, more oral behaviors, sleep disorders, and sleep bruxism. Sleep bruxism was diagnosed more frequently in students who presented moderate or high levels of anxiety, oral behaviors, and sleep disorders. The frequency of TMD reported was higher in students with SB, as well as in those with AB. In conclusion, lifestyle, moderate and high anxiety levels, and sleep disorders are associated with a higher prevalence of AB and SB. Furthermore, AB and SB are associated with a higher frequency of TMD reporting.