bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of preterm birth and birth size status with neurodevelopmental and psychiatric disorders in spontaneous births
Authors: Kong Linghua , Nivins Samson , Chen Xinxia , Liang Yajun , Gissler Mika , Lavebratt Catharina 
Published: June 2024

Abstract
Preterm birth (PTB) or small birth size are risk factors for certain neurodevelopmental disorders. The magnitude of these associations in spontaneous births, and of associations for combined PTB and birth size status on neurodevelopmental and psychiatric disorders is unexplored. We investigated whether PTB and small/large for gestational age (SGA/LGA), separately or combined, in spontaneous births, are associated with a wide spectrum of neurodevelopmental and psychiatric disorders. In this population-based registry cohort study, all singleton spontaneous births in Finland from 1996 to 2014 were followed until 2018 (n = 819 764). We show that PTB across gestational ages, and SGA, were associated with higher risks for anxiety disorders, intellectual disabilities, specific developmental disorders (SDD), autism spectrum disorders (ASD), attention-deficit/hyperactivity disorders (ADHD) and other emotional and behavioural disorders (F98). Most of these associations were not attributed to familial factors. Larger effect sizes were observed with lower gestational ages. Extremely PTB was associated at highest risks with intellectual disabilities (HR, 10.70 [95%CI, 8.69–13.17]) and SDD (HR, 8.91 [95%CI, 8.18–9.71]). Moreover, very preterm birth combined with SGA was associated with a higher risk for SDD (HR, 7.55 [95%CI, 6.61–8.62]) than that of very preterm or SGA birth alone. Conversely, LGA birth lowered the risk for SDD and other emotional and behavioural disorders among individuals born very preterm. In conclusion, PTB along with SGA is associated with higher risks for SDD than one exposure alone, whereas LGA lowers the risks for SDD and other emotional and behavioural disorders in individuals born spontaneously.
Plant Multi-element Coupling as an Indicator of Nutritional Mismatches Under Global Change
Authors: Ochoa-Hueso Raúl , Piñeiro Juan , Morán Lidia Gómez , Serrano-Grijalva Lilia , Power Sally A. 
Published: June 2024

AbstractGlobal biogeochemical cycles have been widely altered due to human activities, potentially compromising the ability of plants to regulate their metabolism. We grew experimental herbaceous communities simulating the understory of eucalypt forests from southeastern Australia to evaluate the effects of elevated CO2 (400 vs. 650 ppm) and changes in soil resource availability (high-low water and high-low P) on the concentration of fourteen essential plant macro- and micronutrients, and their degree of coupling. Coupling was based on correlations among all elements in absolute value and a null modeling approach. According to the ancient nature of Australian soils, P addition was the main driver of changes in plant tissue chemistry, increasing the concentrations of P, Mg, Ca, and Mn and reducing the concentrations of C, N, S, Na, and Cu. Most treatment combinations showed coupled patterns of plant elements, particularly under ambient CO2. However, under elevated CO2, elements in plant tissues became more decoupled, which was interpreted as the result of a lack of enough supply of a range of elements to satisfy greater demands. Across treatments, P, Mn, and N were the least coupled elements, while K, Ca, and Fe were the most coupled ones. We provide evidence that plant element coupling was positively related to the concentration and coupling of elements measured in soils worldwide, suggesting that plant element coupling is conserved. Our results provide compelling evidence that evaluating the coupling of a representative range of chemical elements in plant tissues may represent a highly novel and powerful indicator of nutritional mismatches between demand and supply under specific environmental circumstances, including in a resource-altered global change context.
Fractal discrete fracture network modeling of radon gas concentration in underground tunnels under Książ Castle in Poland
Authors: Fijałkowska–Lichwa Lidia , Ajayi Kayode M. 
Published: June 2024

AbstractThe numerical modeling of radon concentrations in the fault zone of the underground excavations at Książ Castle was conducted using a stochastic Discrete Fracture Network (DFN) model. Due to the difficulties related with obtaining the exact fractures in a rock mass, the novel approach used in this study incorporates the stochastic model with known site data. The analysis utilized a dataset comprising long-term measurements of 222Rn activity concentration and geodetic measurements for twelve faults in the Książ unit. The parameters considered in the DFN model are: fracture length, Peclet number (Pe = 0.1 and 1.0, respectively), advection velocities (from 10–8 m/s to 10–6 m/s and from range from 10–7 m/s to 10–4 m/s, respectively), radon diffusion (D = 2.1 × 10–61/s), radon decay constant (λ = 1/s), and radon gas generation (q) along the fractures within the range of 1.5 × 10–3 Bq/m3·s to 3.5 × 10–3 Bq/m3·s. The calibration process obtained the best fit when the radon generation rate was uniformly distributed through the rock mass in addition to incorporating a higher value of radon generation rate (q = 3.0 × 10–3 Bq/m3·s) where elevated radon concentrations have been measured. The modeling results also confirmed that the radon generation rate should always be higher where elevated radon activity concentrations were measured regardless of the measurement period. For the indicated “area” the radon generation rate should be higher from 25% to 37.5% between May–October and 18.5% to 40% between November–April. The influence of fracture zones on the recorded radon activity concentrations was noticeable up to a depth of 15 m. Within this range, the highest values of 222Rn activity concentration, ranging from 1,600 Bq/m3 to 2,000 Bq/m3, were consistently observed regardless of the season. However, as the depth increased, the values of 222Rn activity concentration decreased from 800 Bq/m3 to 400 Bq/m3 and became more dispersed.
Float, fly, then sink: wetland plant seed buoyancy is lost after internal dispersal by waterbirds
Authors: Navarro-Ramos María J. , Green Andy J. , de Vries Robin , van Leeuwen Casper H. A. 
Published: June 2024

AbstractSeed dispersal distance is an important indicator of how well a plant species can cope with environmental changes. Seeds of wetland plants are primarily dispersed by hydrochory (floating on the water surface) or endozoochory (ingestion and egestion by animals). However, both mechanisms can also be combined (diplochory), which increases dispersal distances. In wetlands, seeds often float on the water surface before ingestion and transport by animals, such as waterbirds. Here, we consider what happens next after endozoochory and test whether seeds dispersed inside waterbirds can then continue to disperse by hydrochory. We experimentally assessed the buoyancy capacity of 41 wetland plant species for 14 weeks before and after simulated passage through avian digestive systems. This revealed that (1) seeds of plants previously assigned a hydrochory dispersal syndrome floated longer than those from other syndromes, but with considerable overlap; (2) fully aquatic and shoreline plant species had seeds with stronger buoyancy than terrestrial plants; and (3) digestive processes negatively affected seed buoyancy capacity for all plant species, which included wetland species with a typical hydrochory syndrome. The capacity for hydrochory is more limited after endozoochory than beforehand, with strong implications for the effectiveness of seed dispersal.
Structure and functional implications of photoreceptive systems in non-marine ostracods: a review
Authors: Bellavere Elena , Matzke-Karasz Renate , Romano Donato , Rossetti Giampaolo 
Published: June 2024

AbstractOstracods are small, bivalved crustaceans living in all types of aquatic habitats. All non-marine species belong to the order Podocopida. They usually possess a simple optical system composed of three eyecups called naupliar eye. Phylogenetic data and morphological characteristics support the homology of naupliar eyes between ostracods and other crustacean groups. The photoreceptive system is formed by several specialised cells and can be approximated by a lens-mirror optical apparatus. In some cases, a transparent area of the calcitic carapace can form an additional lens. The visual stimuli are processed by the protocerebrum, possibly via monoaminergic neurons. The presence or absence of one or more specialised cells influence the function of the eyes, and, most likely, their evolution or loss are associated with the adaptation to different habitats. Podocopid ostracods may express long wavelength-sensitive rhabdomeric opsins and may possess nonvisual opsins. The few ethological experiments so far conducted demonstrate that non-marine ostracods might be capable of associative learning when trained with light or specific light wavelengths. This work will provide an overview of what is known and what remains to be further investigated about vision and how light cues affect the behaviour in non-marine ostracods.
Crystallization experiments of the wheel-and-axle host compound, 1,4-phenylene-bis(di-p-tolylmethanol), from pyridine and methylpyridine mixtures
Authors: Barton Benita , Vorgers Jarryd A. , Hosten Eric C. 
Published: June 2024

Abstract1,4-Phenylene-bis(di-p-tolylmethanol) (H), a host compound with the wheel-and-axle design, formed complexes with organic guest solvents pyridine (PYR) and 2-, 3- and 4-methylpyridine (2MP, 3MP and 4MP). The host: guest (H: G) ratios were 1:3, 1:2, 1:2 and 1:1, respectively. Host crystallization experiments from mixed guests demonstrated H to prefer both PYR and 4MP; however, it was established that these difficult-to-separate (by fractional distillations) guest mixtures cannot be purified/separated by means of H through supramolecular chemistry strategies owing to these selectivities for PYR and 4MP being less than optimal. Single crystal X-ray diffraction experiments showed that each guest compound was held in its complex by means of a classical hydrogen bond with H, and that one of the preferred guests, PYR, experienced a significantly shorter contact of this type than the other guests. Hirshfeld surface analyses demonstrated that PYR was also involved in a greater percentage of (guest)N···H(host) interactions compared with the other guest molecules. Thermal analyses, on the other hand, revealed that 4MP (also a favoured guest species) formed the most stable complex of the four in this investigation. These results with H were compared to those obtained when employing a closely related host compound from a previous report, 1,4-bis(diphenylhydroxymethyl)benzene: while both host species preferred the same guests (PYR and 4MP), the extent of the selectivity of that host compound compared with H in the present work was significantly more enhanced. Thus, minor modifications may deleteriously affect the selectivity behaviour of closely related host compounds.
A contextual integrity approach to genomic information: what bioethics can learn from big data ethics
Authors: de Groot Nina F. 
Published: June 2024

AbstractGenomic data is generated, processed and analysed at an increasingly rapid pace. This data is not limited to the medical context, but plays an important role in other contexts in society, such as commercial DNA testing, the forensic setting, archaeological research, and genetic surveillance. Genomic information also crosses the borders of these domains, e.g. forensic use of medical genetic information, insurance use of medical genomic information, or research use of commercial genomic data. This paper (1) argues that an informed consent approach for genomic information has limitations in many societal contexts, and (2) seeks to broaden the bioethical debate on genomic information by suggesting an approach that is applicable across multiple societal contexts. I argue that the contextual integrity framework, a theory rooted in information technology and big data ethics, is an effective tool to explore ethical challenges that arise from genomic information within a variety of different contexts. Rather than focusing on individual control over information, the contextual integrity approach holds that information should be shared and protected according to the norms that govern certain distinct social contexts. Several advantages of this contextual integrity approach will be discussed. The paper concludes that the contextual integrity framework helps to articulate and address a broad spectrum of ethical, social, and political factors in a variety of different societal contexts, while giving consideration to the interests of individuals, groups, and society at large.
Real-time explicit co-simulation of wire-rope systems for industrial mobile harbor cranes
Authors: Mohammadi Narges , Rouvinen Asko , Korkealaakso Pasi , Escalona José L. 
Published: June 2024

AbstractThis paper presents an investigation into the real-time explicit co-simulation of mobile harbor cranes under hoisting operation. The system is divided into two subsystems, with Subsystem 1 representing the payload and Subsystem 2 encompassing the wire-rope system. To capture the real-time behavior of the wire ropes accurately, the ALEM (Arbitrary Lagrangian–Eulerian Modal) method is employed in this study. Using this formulation, the intricate behavior of the wire ropes, encompassing elasticity, bending effects, and dynamic influences, is rigorously considered. The dynamic equations governing the payload are solved using the Runge–Kutta4 method, while the Generalized Alpha method is utilized to solve the wire-rope system. Both the Gauss–Seidel and Jacobi methods are investigated as two coupling techniques to connect the subsystems. Additionally, the study delves into the impact of the extrapolation method and macro time step on results accuracy and efficiency. The findings demonstrate that co-simulation employing the Gauss–Seidel method and FOH (First-Order Hold) extrapolation yields optimum and accurate simulations. Moreover, the study successfully achieves real-time simulation by optimizing the wire-rope system simulation, accounting for all degrees of freedom inherent in a 3D system. Remarkably, the maximum error observed in the axial force amounts to a mere 0.6% when employing real-time simulation. These findings can hold practical value for employing the current wire-rope subsystem in the interface modeling of real-world industrial cranes.
Translation and linguistic validation of 24 PROMIS item banks into French
Authors: Ahmed Sara , Parks-Vernizzi Emily , Perez Barbara , Arnold Benjamin , Boucher Abigail , Hossenbaccus Mushirah , Correia Helena , Bartlett Susan J. 
Published: June 2024

Abstract
Purpose
The Patient-Reported Outcome Measurement Information System (PROMIS®) was developed to provide reliable, valid, and normed item banks to measure health. The item banks provide standardized scores on a common metric allowing for individualized, brief assessment (computerized adaptive tests), short forms (e.g. heart failure specific), or profile assessments (e.g. PROMIS-29). The objective of this study was to translate and linguistically validate 24 PROMIS adult item banks into French and highlight cultural nuances arising during the translation process.

Methods
We used the FACIT translation methodology. Forward translation into French by two native French-speaking translators was followed by reconciliation by a third native French-speaking translator. A native English-speaking translator fluent in French then completed a back translation of the reconciled version from French into English. Three independent reviews by bilingual translators were completed to assess the clarity and consistency of terminology and equivalency across the English source and French translations. Reconciled versions were evaluated in cognitive interviews for conceptual and linguistic equivalence.

Results
Twenty-four adult item banks were translated: 12 mental health, 10 physical health, and two social health. Interview data revealed that 577 items of the 590 items translated required no revisions. Conceptual and linguistic differences were evident for 11 items that required iterations to improve conceptual equivalence and two items were revised to accurately reflect the English source.

Conclusion
French translations of 24 item banks were created for routine clinical use and research. Initial translation supported conceptual equivalence and comprehensibility. Next steps will include validation of the item banks.
Growing Old, but Paying Back: Understanding How Age Influences Corporate Social Innovation Depth and Breadth of Multinationals in Weak Institutional Contexts
Authors: Attah-Boakye Rexford , Adams Kweku , Yu Honglan , Mali Dafydd , Lim Hyoungjoo 
Published: June 2024

AbstractCorporate Social Innovation (CSI) has emerged as a research priority for multinational enterprises (MNEs) due to the increasing popularity of sustainable development solutions addressing wicked problems in the 21st century. Although most studies on CSI have focused on data from developed economies, emphasising the younger generation's forward-looking, sustainable, and environmentally friendly attitudes, there exists a gap in our understanding of the attitude of the older generation towards CSI practices of MNEs operating in emerging economies. The UN's SDG 3 advocates for the well-being of all at all ages. Despite this, healthcare outcomes in global-south countries fall below standard. Therefore, we conducted an in-depth critical analysis of textual data concerning CSI practices of 115 healthcare MNEs operating in 13 emerging economies. We quantified the number of CSI practices in their annual reports and operationalised the dependent variable using an entropy index to calculate the density and percentage score of CSI. Drawing on Upper Echelons, our analysis revealed that older CEOs are likelier to promote, initiate, and implement CSI in greater depth and breadth. These findings present a compelling case supporting the argument that CEOs and board members tend to contribute more to society as they age. We offer empirical evidence supporting the strengthening roles of senior board members and female board chairs. Our findings complement existing CSI studies from developed countries and illustrate how CEO and board characteristics influence the depth and breadth of CSI in emerging economies.
Superior In Vivo Wound-Healing Activity of Biosynthesized Silver Nanoparticles with Nepeta cataria (Catnip) on Excision Wound Model in Rat
Authors: Sari Berfin Rumeysa , Yesilot Sukriye , Ozmen Ozlem , Aydin Acar Cigdem 
Published: June 2024

AbstractSilver nanoparticles were biosynthesized with Nepeta cataria plant extract. It was determined that the synthesized Nc-AgNPs gave a strong absorbance peak at 438 nm wavelength in the UV-vis spectrophotometer. SEM and TEM analyses of Nc-AgNPs showed that the synthesized nanoparticles had a spherical morphology. Based on XRD analysis, the average crystallite size of Nc-AgNPs was calculated at 15.74 nm. At the same time, EDS spectrum analysis exhibited dominant emission energy at 3 keV, indicative of Nc-AgNPs. Nc-AgNPs showed an inhibition zone of 12 nm in gram-negative Escherichia coli, 10 nm in gram-positive Enterococcus faecalis, and 11 nm in Staphylococcus aureus. Nc-AgNPs showed high antioxidant properties, with 63% at 5000 μg/mL. The wound-healing properties of Nc-AgNPs were evaluated in vivo in wound models created in a total of 20 Wistar albino male rats, divided into four groups. After 10 days of treatment, the highest wound closure rate was seen in the Nc-AgNP + Vaseline (Group IV) treatment group, at 94%. It was observed that Nc-AgNP + Vaseline nanoformulation significantly increased wound healing, similar to Silverdin®, and Vaseline alone supported healing but did not result in complete closure. Histopathological examination revealed an increase in mature Type 1 collagen in Group IV and positive control (Group II), with better collagen maturation in vehicle control (Group III) compared to negative control (Group I). Immunohistochemical analysis showed complete epithelialization in Group IV and Group II, with distinct cytokeratin expressions, while Group III exhibited mild expressions.
Psychometric Validation of the Modified Functional Scale for the Assessment and Rating of Ataxia (f-SARA) in Patients With Spinocerebellar Ataxia
Authors: Potashman Michele , Popoff Evan , Powell Lauren , Mackenzie Ainsley , Beiner Melissa Wolfe , Coric Vlad , Schmahmann Jeremy , L’Italien Gilbert 
Published: June 2024

AbstractThis study aimed to generate evidence to support psychometric validity of the modified functional Scale for the Assessment and Rating of Ataxia (f-SARA) among patients with spinocerebellar ataxia (SCA). Psychometric measurement properties and minimal change thresholds of the f-SARA were evaluated using data from a cohort of SCA subjects (recruited at Massachusetts General Hospital [MGH]; n = 33) and data from a phase 3 trial of troriluzole in adults with SCA (NCT03701399 [Study 206]; n = 217), including a subset of patients with the SCA3 genotype (n = 89). f-SARA item ceiling effects were absent within the MGH cohort, while floor effects were present. Excellent internal consistency reliability was demonstrated (αtotal = 0.90; αitems-removed = 0.86–0.90), and item-to-total correlations were strong (r = 0.82–0.91, per item). High test–retest reliability was demonstrated with intraclass correlation coefficients of 0.91 (total) and 0.73–0.92 (items). Convergent and divergent validity was supported, with strong correlations observed between the f-SARA and similarly constructed scales (FARS-FUNC, BARS, PROM-ADL, and FARS-ADL; all p < 0.001) and weaker correlations observed among measures of differing constructs. Mean item and total scores increased with disease severity (by FARS-FUNC quartile; p < 0.001). A 1-point threshold for meaningful changes was supported as 0.5 × SD = 0.89, SEM = 1.12, and mean changes from baseline for patients classified as “improved,” “no change,” or “deteriorated” were −0.68, 0.02, and 0.58, respectively. Similar trends were observed in Study 206 all-SCA and SCA3 cohorts. The measurement properties of the f-SARA provide evidence of its psychometric validity, responsiveness, and suitability as a clinical outcome measure in patients with SCA, including those with SCA3.
A journey towards teacher empowerment in differentiated instruction: implications for a sustainable teacher professional development model
Authors: Liang Weijun , To Jessica , Lo Yuen Yi 
Published: June 2024

AbstractThis article reports a longitudinal case study examining how teachers were empowered to develop their professional capacity to cater for learner diversity through implementing differentiated instruction. Data were collected from multiple sources including lesson co-planning meetings, teacher interviews and lesson observations in a primary school in Hong Kong. The findings suggested a three-stage journey towards teacher empowerment mediated by both external and internal factors. The findings also highlighted the potential interplay of teacher empowerment, teacher professional development and its sustainability, shedding light on a sustainable model for teacher professional development.