bluuebunny/crossref_metadata_2025_split huggingface dataset:
Not Running Wild With the CISG
Authors: Lookofsky Joseph 
Published: June 2012

In determining the boundaries of supranational legislation some courts adopt an expansionist (dynamic) line. To take a well-known regional example, the European Court of Justice (ECJ) has long been engaged in an exercise in expansionist interpretation, thus broadening the scope of European Union legislation at the expense of the political discretion of EU Member States. Though surely seeking to advance what it sees as the Union’s best interests, the ECJ sometimes “runs amok,” actively extending regional rules in ways that constrain national sovereignty beyond what the Members had originally intended. Or, as one of my Copenhagen colleagues once put it: the ECJ is “running wild.”
Rome I Regulation a—Mostly—Unified Private International Law of Contractual Relationships within—Most—of the European Union
Authors: Volker Behr 
Published: June 2012

The year 2009 was an important year in the development of unified private international law in the European Union. At the beginning of the year, Regulation (EC) No. 864/2007 on the law applicable to non-contractual obligations (Rome II) entered into force. And at the end of the year Regulation (EC) 593/2008 on the law applicable to contractual obligations (Rome I) followed suit. Hence, within one year significant parts of the private international law relevant to international business transactions have been unified within most of the Member States of the European Union. Further segments are to follow up on these developments.
Changes in Whole Blood Viscosity at Low Shear Rates Correlate with Intravascular Volume Changes during Hemodialysis
Authors: Kim Won , Park Sung Kwang , Kang Kyung Pyo , Lee Dong Hwan , Kim Sam Yeon , Jung Jin Mu , Cho Young I. 
Published: June 2012

Background: Elevated blood viscosity has been shown to be independently correlated with cardiovascular risk factors and associated with increased risk of major cardiovascular events, including death and acute myocardial infarction. The aim of the present study was to investigate changes in whole blood viscosity (WBV) at shear rates of 1, 5, and 300 s-1 before and after hemodialysis in patients with end-stage renal disease (ESRD). We also examined the relationship between the changes of WBV and intravascular blood volume. Methods: 43 patients with ESRD receiving maintenance hemodialysis were enrolled. WBV was measured using a scanning capillary tube viscometer pre- and post-dialysis to quantify dialytic viscosity surges. Body weight, blood pressure, and hematocrit were also measured before and after hemodialysis, as was the fluid removed during the session. Results: Hemodialysis had a 3 times greater impact on the low-shear WBV at a shear rate of 1 s-1 (i.e., 44.1% change) than on the high-shear WBV at a shear rate of 300 s-1 (i.e., 15.9% change). Changes in the low-shear WBV obtained at shear rates of 1 and 5 s-1 during hemodialysis were significantly correlated with changes in hematocrit. The intravascular blood volume reduction during hemodialysis was positively correlated with the changes in both high-shear and low-shear WBVs. Conclusions: These results suggest that the WBV parameter may hold additional information beyond hemoconcentration. Further research is needed to evaluate the relationship between low-shear WBV surges and increased morbidity in the patient population with ESRD.
Rare inherited A2BP1 deletion in a proband with autism and developmental hemiparesis
Authors: Davis L.K. , Maltman N. , Mosconi M.W. , Macmillan C. , Schmitt L. , Moore K. , Francis S.M. , Jacob S. , Sweeney J.A. , Cook E.H. 
Published: June 2012

AbstractAtaxin 2 binding protein 1 (A2BP1 aka FOX1, RBFOX1) is an RNA binding protein responsible for regulation of pre‐mRNA splicing events in a number of critical developmental genes expressed in muscle, heart and neuronal cells [Shibata et al. (2000); Mamm Genome 12:595–601; Jin et al. (2003); EMBO J 22:905–912; Underwood et al. (2005); Mol Cell Biol 25:10005–10016]. Rare copy number abnormalities of A2BP1 have been previously associated with cognitive impairment, attention deficit disorder and autism [Martin et al. (2007); Am J Med Gen Part B 144B:869–876; Elia et al. (2010); Mol Psychiatry 15:637–646.]. Using a 1M Illumina SNP microarray, we identified a 1.3 kb deletion in A2BP1, which was subsequently validated by quantitative PCR. Here we present an in depth case study of an individual with autism and mild developmental hemiparesis in whom the deletion was detected. This study provides further support for the possible role of rare copy number variants in A2BP1 in the development of autism and associated motor asymmetries. © 2012 Wiley Periodicals, Inc.
Proposal of a clinical score for the molecular test for Pitt–Hopkins syndrome
Authors: Marangi Giuseppe , Ricciardi Stefania , Orteschi Daniela , Tenconi Romano , Monica Matteo Della , Scarano Gioacchino , Battaglia Domenica , Lettori Donatella , Vasco Gessica , Zollino Marcella 
Published: June 2012

AbstractPitt–Hopkins syndrome (PTHS) is an emerging condition characterized by severe intellectual disability (ID), typical facial gestalt, and additional features, such as breathing abnormalities. Because of the overlapping phenotype of severe ID with absent speech, epilepsy, microcephaly, large mouth, and constipation, differential diagnosis of PTHS with respect to Angelman, Rett, and Mowat–Wilson syndromes represents a relevant clinical issue, and many patients are currently undergoing genetic tests for different conditions that are assumed to fall within the PTHS clinical spectrum. During a search for TCF4 mutations in 78 patients with a suspected PTHS, haploinsufficiency of TCF4 was identified in 18. By evaluating clinical features of patients with a proven TCF4 mutation with those of patients without, we noticed that, in addition to the typical facial gestalt, the PTHS phenotype results from the various combination of the following characteristics: ID with severe speech impairment, normal growth parameters at birth, postnatal microcephaly, breathing abnormalities, motor incoordination, ocular anomalies, constipation, seizures, typical behavior, and subtle brain abnormalities. On the basis of these observations, here we propose a clinically based score system as useful tool for driving a first choice molecular test for PTHS. This scoring system is also proposed for a clinically based diagnosis of PTHS in absence of a proven TCF4 mutation. © 2012 Wiley Periodicals, Inc.
Severe plexiform facial neurofibromatosis, type 1 with underdeveloped eyes and a novel NF1 mutation
Authors: Kantaputra Piranit Nik , van den Ouweland Ans , Sangruchi Tumtip , Limwongse Chanin 
Published: June 2012

AbstractA Thai woman, who was affected with neurofibromatosis type 1, was followed up and re‐evaluated at ages 45, 61, and 67 years. Her mother and her three brothers were also affected. The proposita was very severely affected. She was born blind with underdeveloped eyeglobes and had large plexiform neurofibromas on her face. Her eyelids were gigantic and tears drained from the orifice between them. Cutaneous neurofibromas were observed all over her body. A novel mutation c.4821delA was identified in NF1 gene, which predicted truncation of neurofibromin (p.Leu1607fs). © 2012 Wiley Periodicals, Inc.
Molecular characterization of 1q44 microdeletion in 11 patients reveals three candidate genes for intellectual disability and seizures
Authors: Thierry Gaelle , Bénéteau Claire , Pichon Olivier , Flori Elisabeth , Isidor Bertrand , Popelard Françoise , Delrue Marie‐Ange , Duboscq‐Bidot Laetitia , Thuresson Ann‐Charlotte , van Bon Bregje W.M. , Cailley Dorothée , Rooryck Caroline , Paubel Agathe , Metay Corinne , Dusser Anne , Pasquier Laurent , Béri Mylène , Bonnet Céline , Jaillard Sylvie , Dubourg Christèle , Tou Bassim , Quéré Marie‐Pierre , Soussi‐Zander Cecilia , Toutain Annick , Lacombe Didier , Arveiler Benoit , de Vries Bert B.A. , Jonveaux Philippe , David Albert , Le Caignec Cédric 
Published: June 2012

AbstractPatients with a submicroscopic deletion at 1q43q44 present with intellectual disability (ID), microcephaly, craniofacial anomalies, seizures, limb anomalies, and corpus callosum abnormalities. However, the precise relationship between most of deleted genes and the clinical features in these patients still remains unclear. We studied 11 unrelated patients with 1q44 microdeletion. We showed that the deletions occurred de novo in all patients for whom both parents' DNA was available (10/11). All patients presented with moderate to severe ID, seizures and non‐specific craniofacial anomalies. By oligoarray‐based comparative genomic hybridization (aCGH) covering the 1q44 region at a high resolution, we obtained a critical deleted region containing two coding genes—HNRNPU and FAM36A—and one non‐coding gene—NCRNA00201. All three genes were expressed in different normal human tissues, including in human brain, with highest expression levels in the cerebellum. Mutational screening of the HNRNPU and FAM36A genes in 191 patients with unexplained isolated ID did not reveal any deleterious mutations while the NCRNA00201 non‐coding gene was not analyzed. Nine of the 11 patients did not present with microcephaly or corpus callosum abnormalities and carried a small deletion containing HNRNPU, FAM36A, and NCRNA00201 but not AKT3 and ZNF238, two centromeric genes. These results suggest that HNRNPU, FAM36A, and NCRNA00201 are not major genes for microcephaly and corpus callosum abnormalities but are good candidates for ID and seizures. © 2012 Wiley Periodicals, Inc.
Progressive polyepiphyseal dysplasia with arthropathy: A distinct disorder from idiopathic juvenile arthritis and pseudorheumatoid dysplasia?
Authors: Isidor Bertrand , Poignant Sylvaine , Picherot Georges , Mégabarné André , Quartier Pierre , Bader‐Meunier Brigitte , Le Caignec Cédric , Le Merrer Martine , Baujat Geneviève , Cormier‐Daire Valérie , David Albert 
Published: June 2012

AbstractJuvenile idiopathic arthritis is an inflammatory disease with various onset‐forms which can sometimes be difficult to distinguish from genetic inflammatory/rheumatoid‐like osteoarthropathies. In this report, we describe two boys with severe chronic arthralgia, stiffness and swelling of joints, motor weakness and joints contractures evolving despite immunosuppressive treatments and for whom all biological and molecular exams failed to identify a prompt diagnosis. Some findings also overlap with pseudorheumatoid dysplasia but WISP3 gene molecular analysis failed to identify any mutation for both patients. Therefore, we propose that these boys show a clinical entity distinct from the actually known genetic inflammatory/rheumatoid‐like osteoarthropathies. © 2012 Wiley Periodicals, Inc.
Studies on the preparation of Parinari polyandra benth seed oil alkyd resins
Authors: Odetoye T. E. , Ogunniyi D. S. , Olatunji G. A. 
Published: June 2012

AbstractParinari polyandra Benth seed oil was utilized in the preparation of four sets of alkyd resin (35%, 50%, 60%, and 75% oil formulations) using a two‐stage alcoholysis‐polyesterification method. The rate of polyesterification was depended on the amount of oil used during synthesis. The properties of the alkyds (drying times, film characteristics, water and acid resistances, and solubility) were evaluated using relevant standards. Inclusion of cobalt naphthenate drier in the alkyds and their exposure to outdoor temperature improved the drying properties. White gloss paints formulated from the alkyds, considering a pigment‐volume concentration of 20.67% in the gloss paint formulation compare well with commercial standard. FTIR and 1H‐NMR analysis confirm the alkyd (glycerol‐phthalate) structure. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Catalytic oxidation of thioanisole using oxovanadium(IV)‐functionalized electrospun polybenzimidazole nanofibers
Authors: Walmsley Ryan S. , Hlangothi Percy , Litwinski Christian , Nyokong Tebello , Torto Nelson , Tshentu Zenixole R. 
Published: June 2012

AbstractPolybenzimidazole fibers, with an average diameter of 262 nm, were produced by the process of electrospinning. These fibers were used as a solid support material for the immobilization of oxovanadium(IV) which was achieved via a reaction with vanadyl sulfate. The oxovanadium(IV)‐functionalized nanofibers were used as heterogeneous catalysts for the oxidation of thioanisole under both batch and pseudo‐continuous flow conditions with great success. Under batch conditions near quantitative oxidation of thioanisole was achieved in under 90 min, even after four successive catalytic reactions. Under continuous conditions, excellent conversion of thioanisole was maintained throughout the period studied at flow rates of up to 2 mLh−1. This study, therefore, proposes that electrospun polybenzimidazole nanofibers, with their small diameters, impressive chemical and thermal stability, as well as coordinating benzimidazole group, may be a desirable support material for immobilization of homogeneous catalysts. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Arthropod venoms: A vast arsenal of insecticidal neuropeptides
Authors: Schwartz Elisabeth F. , Mourão Caroline B. F. , Moreira Karla G. , Camargos Thalita S. , Mortari Márcia R. 
Published: June 2012

AbstractArthropods are the most diverse animal group on the planet, and occupy almost all ecological niches. Venomous arthropods are a rich source of bioactive compounds evolved for prey capture and defense against predators and/or microorganisms. These highly potent chemical arsenals represent an available source for new insecticidal compounds as they act selectively on their molecular targets. These toxins affect the invertebrate nervous system and, until the moment, several insecticidal compounds belonging to the class of peptides or polyamine‐like compounds have been purified and characterized from the venom of arachnids and hymenopterans. This review focuses on invertebrate‐specific peptide neurotoxins that have been isolated from the venom of spiders, scorpions, centipedes, ants, and wasps, discussing their potential in pest control and as invaluable tools in neuropharmacology. © 2012 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 98: 385‐405, 2012.
Comparisons of CES‐D depression scoring methods in two older adults ethnic groups. The emergence of an ethnic‐specific brief three‐item CES‐D scale
Authors: Coman Emil N. , Iordache Eugen , Schensul Jean J. , Coiculescu Ion 
Published: June 2012

ObjectiveTo compare the reliabilities and convergent validities of five CES‐D (Center for Epidemiologic Studies Depression) composite scores in two ethnic/racial groups of community‐dwelling older adults.DesignCES‐D measurement equivalence was tested with Structural Equation Modeling in Puerto‐Rican (PR) and African American (AA) older adults, then reliabilities of five composite scores and their convergent validities were compared.FindingsBayesian CES‐D scores had the highest reliabilities, followed by software estimated factor scores, the unit weight, and the weighted scores. Bayesian CES‐D scores, factor scores, and surprisingly a group‐specific three‐item brief CES‐D score exhibited better convergent validity than the unit‐weight and weighted CES‐D scores.ConclusionsAn ethnic group‐specific three‐item brief CES‐D score emerged as a reliable CES‐D measure in PR and AA older adults. We conclude that practitioners could emphasize three main symptoms in individual older adults in screening for depression, and researchers can model with confidence the relationships between the CES‐D brief scale and its correlates. Copyright © 2012 John Wiley & Sons, Ltd.
Mass balance loss of Mount Baker, Washington glaciers 1990–2010
Authors: Pelto Mauri , Brown Courtenay 
Published: June 2012

AbstractMount Baker, North Cascades, WA, has a current glacierized area of 38.6 km2. From 1984 to 2010, the North Cascade Glacier Climate Project has monitored the annual mass balance (Ba), accumulation area ratio (AAR), terminus behaviour and longitudinal profiles of Mount Baker glaciers. The Ba on Rainbow, Easton and Sholes Glaciers from 1990 to 2010 averaged −0.52 m w.e. a−1(m a−1). Terminus observations on nine principal Mount Baker glaciers, 1984–2009, indicate retreat ranging from 240 to 520 m, with a mean of 370 m or 14 m a−1. AAR observations on Rainbow, Sholes and Easton Glaciers for 1990–2010 indicate a mean AAR of 0.55 and a steady state AAR of 0.65.A comparison of Ba and AAR on these three glaciers yields a relationship that is used in combination with AAR observations made on all Mount Baker glaciers during 7 years to assess Mount Baker glacier mass balance. Utilizing the AAR–Ba relationship for the three glaciers yields a mean Ba of −0.55 m a−1 for the 1990–2010 period, 0.03 m a−1 higher than the measured mean Ba. The mean Ba based on the AAR–Ba relationship for the entire mountain from 1990 to 2010 is −0.57 m a−1. The product of the mean observed mass balance gradient determined from 11 000 surface mass balance measurements and glacier area in each 100‐m elevation band on Mount Baker yields a Ba of −0.50 m a−1 from 1990–2010 for the entire mountain. The median altitude of the three index glaciers is lower than that of all Mount Baker glaciers. Adjusting the balance gradient for this difference yields a mean Ba of −0.77 m a−1 from 1990 to 2010. All but one estimate converge on a loss of −0.5 m a−1 for Mount Baker from 1990 to 2010. This equates to an 11‐m loss in glacier thickness, 12–20% of the entire 1990 volume of glaciers on Mount Baker. Copyright © 2012 John Wiley & Sons, Ltd.
A Comparison of Logistic Regression and Classification Tree Analysis for Behavioural Case Linkage
Authors: Tonkin Matthew , Woodhams Jessica , Bull Ray , Bond John W. , Santtila Pekka 
Published: June 2012

AbstractMuch previous research on behavioural case linkage has used binary logistic regression to build predictive models that can discriminate between linked and unlinked offences. However, classification tree analysis has recently been proposed as a potential alternative owing to its ability to build user‐friendly and transparent predictive models. Building on previous research, the current study compares the relative ability of logistic regression analysis and classification tree analysis to construct predictive models for the purposes of case linkage. Two samples are utilised in this study: a sample of 376 serial car thefts committed in the UK and a sample of 160 serial residential burglaries committed in Finland. In both datasets, logistic regression and classification tree models achieve comparable levels of discrimination accuracy, but the classification tree models demonstrate problems in terms of reliability or usability that the logistic regression models do not. These findings suggest that future research is needed before classification tree analysis can be considered a viable alternative to logistic regression in behavioural case linkage. Copyright © 2012 John Wiley & Sons, Ltd.
Managing change: Nine common blunders—and how to avoid them
Authors: Toterhi Tim , Recardo Ronald J. 
Published: June 2012

AbstractDespite increased awareness of change management processes, principles, and practices, many business leaders continue to struggle with navigating their organization through a change initiative. These challenges often stem from a series of common blunders that can significantly impede progress in achieving project goals. The experiences of several executive sponsors of large‐scale change, however, show that employing a holistic change management model can help highlight these potential pitfalls so that they can be proactively addressed. A methodology for avoiding these common blunders can be incorporated into any change program to shorten implementation cycle times, enhance stakeholder engagement and commitment, reduce productivity fluctuations during rollout, and, most important, capture targeted benefits. © 2012 Wiley Periodicals, Inc.
Organizational identity via recruitment and communication: Lessons from the International Thermonuclear Experimental Reactor project
Authors: Collins Hilary 
Published: June 2012

AbstractA study of the efforts employed among scientific, engineering, and support staff in the early phases of the International Thermonuclear Experimental Reactor (ITER) project outside Marseille, France, found that the management of communication tools as part of a strategic sense‐giving process enabled the formation of a transitional identity. This eased employees' transition into their new surroundings and fostered their engagement with the organization and its mission. Having implications for both the motivation and retention of employees, the findings show that sense making and sense giving using communication tools affects the pace at which an organization can forge an organizational identity.
© 2012 Wiley Periodicals, Inc.
Identification of physicochemical properties of Scylla paramamosain allergen, arginin kinase
Authors: Yu Hui‐Lin , Ruan Wei‐Wei , Cao Min‐Jie , Cai Qiu‐Feng , Shen Hai‐Wang , Liu Guang‐Ming 
Published: June 2012

AbstractBACKGROUND: Arginine kinase (AK) is expressed in a wide variety of species, including human food sources (seafood) and pests (cockroaches and moths), and has been reported as a novel allergen. However, there has been little research on the allergenicity of AK in crustaceans. In this study the physicochemical properties of AK from mud crab (Scylla paramamosain) were investigated.RESULTS: Analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis, immunoblotting and inhibition enzyme‐linked immunosorbent assay revealed that purified AK was unstable in thermal processing and in acid buffer. Under simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) conditions, purified AK was much more readily degraded by pepsin than by trypsin or chymotrypsin. The unpurified AK in crab myogen degraded more markedly than purified AK. In addition, in two‐phase gastrointestinal digestion, AK was rapidly degraded by pepsin but resistant to trypsin and chymotrypsin digestion, while tropomyosin derived from mud crab was resistant to pepsin digestion but digested readily by trypsin or chymotrypsin. Further study of serum samples obtained from crab‐allergic human patients indicated that the allergenicity of AK was markedly reduced by digestion with SGF but not SIF.CONCLUSION: AK is an important food allergen despite its unstable physicochemical properties of digestibility. Copyright © 2012 Society of Chemical Industry
A new closed‐form solution for analysis of unlined pressure tunnels under seepage forces
Authors: Fahimifar Ahamad , Zareifard Mohammad Reza 
Published: June 2012

SUMMARYIn this study, a simplified analytical closed‐form solution, considering plane strain and axial symmetry conditions, for analysis of a circular pressure tunnel excavated underwater table, is developed. The method accounts for the seepage forces with the steady‐state flow and is based on the generalized effective stress law. To examine the effect of pore pressure variations and also the boundary conditions at the ground surface, the formulations are derived for different directions around the tunnel. The proposed method can be applied for analysis and design of pressure tunnels. Illustrative examples are given to demonstrate the performance of the proposed solution and also to examine the effect of seepage forces on the stability of tunnels. The simplified analytical solution derived in this study is compared with numerical analyses. It is concluded that the classic solutions (Lame's thick‐walled solution), considering the internal pressure as a mechanical load applied to the tunnel surface, are not applicable to pervious media and can result in an unsafe design. Copyright © 2012 John Wiley & Sons, Ltd.