bluuebunny/crossref_metadata_2025_split huggingface dataset:
YIPF3 and YIPF4 regulate autophagic turnover of the Golgi apparatus
Authors: Kitta Shinri , Kaminishi Tatsuya , Higashi Momoko , Shima Takayuki , Nishino Kohei , Nakamura Nobuhiro , Kosako Hidetaka , Yoshimori Tamotsu , Kuma Akiko 
Published: May 2024

AbstractThe degradation of organelles by autophagy is essential for cellular homeostasis. The Golgi apparatus has recently been demonstrated to be degraded by autophagy, but little is known about how the Golgi is recognized by the forming autophagosome. Using quantitative proteomic analysis and two novel Golgiphagy reporter systems, we found that the five-pass transmembrane Golgi-resident proteins YIPF3 and YIPF4 constitute a Golgiphagy receptor. The interaction of this complex with LC3B, GABARAP, and GABARAPL1 is dependent on a LIR motif within YIPF3 and putative phosphorylation sites immediately upstream; the stability of the complex is governed by YIPF4. Expression of a YIPF3 protein containing a mutated LIR motif caused an elongated Golgi morphology, indicating the importance of Golgi turnover via selective autophagy. The reporter assays reported here may be readily adapted to different experimental contexts to help deepen our understanding of Golgiphagy.
Uncovering Gender-Specific and Cross-Gender Features in Mandarin Deception: An Acoustic and Electroglottographic Approach
Authors: Wu Hao-Yu 
Published: May 2024

Purpose:
This study aimed to investigate the acoustic and electroglottographic (EGG) profiles of Mandarin deception, including global characteristics and the influence of gender.

Method:
Thirty-six Mandarin speakers participated in an interactive interview game in which they provided both deceptive and truthful answers to 14 biographical questions. Acoustic and EGG signals of the participants' responses were simultaneously recorded; 20 acoustic and 14 EGG features were analyzed using binary logistic regression models.

Results:

Increases in fundamental frequency (
F
0) mean, intensity mean, first formant (F1), fifth formant (F5), contact quotient (CQ), decontacting-time quotient (DTQ), and contact index (CI) as well as decreases in jitter, shimmer, harmonics-to-noise ratio (HNR), and fourth formant (F4) were significantly correlated with global deception. Cross-gender features included increases in intensity mean and F5 and decreases in jitter, HNR, and F4, whereas gender-specific features encompassed increases in
F
0 mean, shimmer, F1, third formant, and DTQ, as well as decreases in
F
0 maximum and CQ for female deception, and increases in CQ and CI and decreases in shimmer for male deception.

Conclusions:
The results suggest that Mandarin deception could be tied to underlying pragmatic functions, emotional arousal, decreased glottal contact skewness, and more pressed phonation. Disparities in gender-specific features lend support to differences in the use of pragmatics, levels of deception-induced emotional arousal, skewness of glottal contact patterns, and phonation types.
Exploring the Influence of Extended High-Frequency Hearing on Cochlear Functioning at Lower Frequencies
Authors: Mishra Srikanta K. , Rodrigo Hansapani , Balan Jithin R. 
Published: May 2024

Purpose:
Diminished basal cochlear function, as indicated by elevated hearing thresholds in the extended high frequencies (EHFs), has been associated with lower levels of click-evoked and distortion-product otoacoustic emissions measured at lower frequencies. However, stimulus-frequency otoacoustic emissions (SFOAEs) at low-probe levels are reflection-source emissions that do not share the same generation mechanism as distortion-source emissions. The primary objective of the present study was to examine the influence of hearing thresholds in the EHFs on SFOAEs measured at lower frequencies.

Method:
SFOAEs were recorded from both ears in 45 individuals with normal hearing thresholds in the conventional audiometric frequencies (0.25–8 kHz). Hearing thresholds were also measured at EHFs (10, 12.5, and 16 kHz). SFOAE magnitudes and signal-to-noise ratios (SNRs) were averaged across 1, 2, and 4 kHz probe frequencies and also averaged for high-probe frequencies (2 and 4 kHz).

Results:
SFOAE magnitudes and SNRs were significantly higher for ears with better EHF hearing relative to poorer EHF hearing, categorized based on the median split. In addition, hearing in the EHFs significantly contributed to the variance in all SFOAE measures, except for the high-frequency SFOAE magnitudes model. However, hearing thresholds at the probe frequencies did not significantly contribute to the variance in SFOAEs.

Conclusions:
The study findings suggest that alterations in the basal cochlea, as revealed by EHF hearing thresholds, could be associated with diminished cochlear functioning in relatively apical regions, shown by SFOAEs at lower frequencies, in individuals with normal audiograms. These findings underscore the significance of considering EHF thresholds in audiological evaluations, as alterations in these frequencies may reflect broader cochlear health status.
Metabarcoding of protozoa and helminth in black-necked cranes: a high prevalence of parasites and free-living amoebae
Authors: Yu Mengshi , Li Wenhao , He Xin , He Guiwen , Yao Yonfang , Wang Yuanjian , Shao Mingcui , Xiong Tingsong , Xu Huailiang , Zhao Junsong 
Published: May 2024

Parasites and free-living amoebae (FLA) are common pathogens that pose threats to wildlife and humans. The black-necked crane (Grus nigricollis) is a near-threatened species and there is a shortage of research on its parasite diversity. Our study aimed to use noninvasive methods to detect intestinal parasites and pathogenic FLA in G. nigricollis using high-throughput sequencing (HTS) based on the 18S rDNA V9 region. A total of 38 fresh fecal samples were collected in Dashanbao, China, during the overwintering period (early-, middle I-, middle II-, and late-winter). Based on the 18S data, eight genera of parasites were identified, including three protozoan parasites: Eimeria sp. (92.1%) was the dominant parasite, followed by Tetratrichomonas sp. (36.8%) and Theileria sp. (2.6%). Five genera of helminths were found: Echinostoma sp. (100%), Posthodiplostomum sp. (50.0%), Euryhelmis sp. (26.3%), Eucoleus sp. (50.0%), and Halomonhystera sp. (2.6%). Additionally, eight genera of FLA were detected, including the known pathogens Acanthamoeba spp. (n = 13) and Allovahlkampfia spp. (n = 3). Specific PCRs were used to further identify the species of some parasites and FLA. Furthermore, the 18S data indicated significant changes in the relative abundance and genus diversity of the protozoan parasites and FLA among the four periods. These results underscore the importance of long-term monitoring of pathogens in black-necked cranes to protect this near-endangered species.
Genetic Foundation of Prostaglandin Metabolism Influences Patent Ductus Arteriosus Closure in Extremely Low Birth Weight Infants
Authors: Sampath Hannah J. , Krishnan Parvathy , Trinh Van , Parton Lance A. 
Published: May 2024

Objective Prostaglandins (PGs) play a major role in maintaining patency of the ductal arteriosus (DA). Pulmonary 15-hydroxyprostaglandin dehydrogenase (PGDH), which is ecoded by the hydroxyprostaglandin dehydrogenase (HPGD) gene, is the primary enzyme responsible for PG breakdown. Animal studies have shown HPGD-knockout mice have significantly higher prostaglandin E2 levels and no ductal remodeling. Functional variants of the HPGD gene that alter PG breakdown have not been studied in preterm infants with patent ductus arteriosus (PDA).
Study Design This was an observational cohort study including extreme low birth weight (ELBW) infants classified as having spontaneous, medical, or procedural (transcatheter or surgical ligation) closure of their DA. Urine prostaglandin E metabolite (PGEM) levels were measured in ELBW infants following ibuprofen treatment using competitive ELISA. HPGD genetic variants rs8752, rs2612656, and rs9312555 were analyzed. Kruskal–Wallis, Fisher's exact, chi square, logistic regression, and Wilcoxon signed-rank tests were used; p < 0.05 was considered significant.
Results Infants in the procedural closure group had a younger gestational age (GA). The incidence of spontaneous closure or medical closure was higher compared to procedural closure in the presence of any minor allele of rs8752 (67 and 27%, respectively; p = 0.01), when adjusted for GA and gender. Haplotype analysis of three variants of HPGD revealed differences when comparing the spontaneous and medical closure group to the procedural group (p < 0.05). Urinary PGEM levels dropped significantly in those ELBW infants who responded to ibuprofen (p = 0.003) in contrast to those who did not respond (p = 0.5).
Conclusion There was a different genotype distribution for the rs8752 genetic variant of the HPGD gene—as it relates to the mode of treatment for ELBW infants with PDA. We speculate that medical management in the presence of this variant facilitated additional PG breakdown, significantly abrogating the need for procedural closure. Additionally, differences in genotype and haplotype distributions implicate a specific HPGD genetic foundation for DA closure in ELBW infants.
Key Points
The impact of corporate social responsibility in technological innovation on sustainable competitive performance
Authors: Wu Weiwei , Shi Jian , Liu Yexin 
Published: May 2024

AbstractThe twenty-first century has seen an increase in stakeholders, highlighting the need to discuss the role of corporate social responsibility in technological innovation. The objective of the current research is to examine the role that corporate social responsibility in technological innovation plays in enhancing the sustainable competitive performance of firms. The idea that digital transformation mediates the relationship between corporate social responsibility in technological innovation and sustainable competitive performance is proposed in this study. Additionally, the mastery climate may act as a boundary condition that strengthens the positive relationship between CSR and digital transformation. The data were collected in Chinese firms through a questionnaire. The results supported the mediation and moderation hypotheses, confirming that digital transformation mediates the relationship between corporate social responsibility in technological innovation and sustainable competitive performance. The mastery climate moderates the relationship between corporate social responsibility in technological innovation and digital transformation. The results have implications for theory and practice. Limitations and future research directions are also discussed.
The Taiwanese Night Markets through the Lens of the Caribbean Expat Community
Authors: Nava Leonardo , Pemberton Judette 
Published: May 2024

Summary

The night markets have become cultural landmarks in Taiwan. They are not only a ‘must-see’ for tourists but also leisure spaces where local and foreign residents interact regularly. It is key for Taiwan to maintain strong ties with its 13 diplomatic allies, many of whom are Small Islands Developing States (SIDS) in the Caribbean. This situation has turned Taiwan into a unique meeting point for people from distant SIDS. This case study collects the perspectives of the Anglo-Caribbean community residing in Taiwan regarding their experiences with night markets. We conducted interviews and
in situ
observations to gather insights into the initial impressions, motivations for attending, and discouraging experiences at night markets among Caribbean expatriates from Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines (SVG), and Belize. This case study evidences that despite cultural differences, language barriers, and prejudices, the night markets play an important role in the integration process of the expats into Taiwanese society.

Information
© The Authors 2024
Metric perturbations of Kerr spacetime in Lorenz gauge: circular equatorial orbits
Authors: Dolan Sam R , Durkan Leanne , Kavanagh Chris , Wardell Barry 
Published: May 2024

Abstract
We construct the metric perturbation in Lorenz gauge for a compact body on a circular equatorial orbit of a rotating black hole (Kerr) spacetime, using a newly-developed method of separation of variables. The metric perturbation is formed from a linear sum of differential operators acting on Teukolsky mode functions, and certain auxiliary scalars, which are solutions to ordinary differential equations in the frequency domain. For radiative modes, the solution is uniquely determined by the

s
=
±
2

Weyl scalars, the s = 0 trace, and

s
=
0
,
1

gauge scalars whose amplitudes are determined by imposing continuity conditions on the metric perturbation at the orbital radius. The static (zero-frequency) part of the metric perturbation, which is handled separately, also includes mass and angular momentum completion pieces. The metric perturbation is validated against the independent results of a 2+1D time domain code, and we demonstrate agreement at the expected level in all components, and the absence of gauge discontinuities. In principle, the new method can be used to determine the Lorenz-gauge metric perturbation at a sufficiently high precision to enable accurate second-order self-force calculations on Kerr spacetime in future. We conclude with a discussion of extensions of the method to eccentric and non-equatorial orbits.
Magnetization reversal phenomena in thin films presenting stripe domains
Authors: López Duque P , Goijman D , Sarmiento A , Ramírez G , Avilés-Félix L , Gómez J , Pérez Martínez A , Eddrief M , Butera A , Vavassori P , Milano J , Niebieskikwiat D 
Published: May 2024

Abstract
We present a study of the properties related to the magnetization reversal process in two thin-film samples with magnetic stripe domains: Fe0.82Ga0.18 (Fe–Ga) and Ni0.81Fe0.19 (permalloy). In Fe–Ga thin films, we focus on magnetization reversal driven by thermal activation by considering the magnetic viscosity behavior. The results suggest that the reversal process occurs gradually, where the magnetization switches direction via

∼

10

nm-long jumps of the magnetic domain walls. On the other hand, vectorial hysteresis loops were performed in permalloy thin films with the aim to study the behavior of the transverse magnetization component (perpendicular to the applied field) during the magnetization reversal process. We show that the measurement of the transversal magnetization component shows a much higher sensitivity for the determination of the in-plane magnetic anisotropy than the usual hysteresis loops where the magnetization is parallel to the applied field. Moreover, this allows to highlight the competition between the intrinsic and rotatable anisotropies in thin films that present stripe domains.
Detection of miRNA-378 based on a catalytic hairpin self-assembly reaction combined with gold nanoparticle colorimetry
Authors: Zhang Run , Gao Yahui , Wang Shan , Pan Jinru , Geng Shuang , Li Zhen , Zhang Kejie , Meng Wei 
Published: May 2024

Abstract
Recent studies have shown that abnormal miRNA-378 expression is a rule, rather than an exception, in cervical cancer and can be used as a diagnostic and prognostic biomarker to assess tumor initiation. In this study, we developed a general, sensitive strategy for detecting miRNA-378 using catalytic hairpin self-assembly (CHA) combined with gold nanoparticles (AuNP) colorimetry. The presence of miRNA-378 triggers the repeated self-assembly of two designed hairpin DNAs (H1 and H2) into dsDNA polymers, which leads to changes in the surface plasmon resonance absorption band and the macroscopic color of the AuNP colloids due to the formation of nanoparticle-DNA conjugates. This experimental phenomenon can be observed by ultraviolet-visible spectrometry or even with the naked eye. Using this method, miRNA-378 could be quantitatively detected at the picomolar level (as low as 20.7 pM). Compared with traditional methods, such as quantitative polymerase chain reaction and RNA blotting, this strategy has a simple operation, low cost, and high sensitivity and selectivity, and thus, exhibits significant potential for miRNA detection.
Exact global control of small divisors in rational normal form
*
Authors: Liu Jianjun , Xiang Duohui 
Published: May 2024

Abstract
Rational normal form is a powerful tool to deal with Hamiltonian partial differential equations without external parameters. In this paper, we build rational normal form with exact global control of small divisors. As an application to nonlinear Schrödinger equations in Gevrey spaces, we prove sub-exponentially long time stability results for generic small initial data.
Neutrino mass and mixing with modular symmetry
Authors: Ding Gui-Jun , King Stephen F 
Published: May 2024

AbstractThis is a review article about neutrino mass and mixing and flavour model building strategies based on modular symmetry. After a brief survey of neutrino mass and lepton mixing, and various Majorana seesaw mechanisms, we construct and parameterise the lepton mixing matrix and summarise the latest global fits, before discussing the flavour problem of the Standard Model. We then introduce some simple patterns of lepton mixing, introduce family (or flavour) symmetries, and show how they may be applied to direct, semi-direct and tri-direct CP models, where the simple patterns of lepton mixing, or corrected versions of them, may be enforced by the full family symmetry or a part of it, leading to mixing sum rules. We then turn to the main subject of this review, namely a pedagogical introduction to modular symmetry as a candidate for family symmetry, from the bottom–up point of view. After an informal introduction to modular symmetry, we introduce the modular group, and discuss its fixed points and residual symmetry, assuming supersymmetry throughout. We then introduce finite modular groups of levelNand modular forms with integer or rational modular weights, corresponding to simple geometric groups or their double or metaplectic covers, including the most general finite modular groups and vector-valued modular forms, with detailed results forN=2,3,4,5. The interplay between modular symmetry and generalized CP symmetry is discussed, deriving CP transformations on matter multiplets and modular forms, highlighting the CP fixed points and their implications. In general, compactification of extra dimensions generally leads to a number of moduli, and modular invariance with factorizable and non-factorizable multiple moduli based on symplectic modular invariance and automorphic forms is reviewed. Modular strategies for understanding fermion mass hierarchies are discussed, including the weighton mechanism, small deviations from fixed points, and texture zeroes. Then examples of modular models are discussed based on single modulusA4models, a minimalS4′model of leptons (and quarks), and a multiple moduli model based on threeS4groups capable of reproducing the Littlest Seesaw model. We then extend the discussion to include Grand Unified Theories based on modular (flipped)SU(5) andSO(10). Finally we briefly mention some issues related to top–down approaches based on string theory, including eclectic flavour symmetry and moduli stabilisation, before concluding.
Terahertz wave propagation characteristics in SMM-based three-dimensional plasma fluid
Authors: Zhang Jie , Wang Zhengfang , Li Miao , Li Mingzhao 
Published: May 2024

Abstract
During the return to the atmosphere of a hypersonic vehicle in adjacent space, a plasma sheath forms on the surface of the vehicle, which blocks normal electromagnetic communications. The ‘blackout’ phenomenon caused by plasma sheaths has received much attention. This paper focuses on the American RAM-C vehicle as the research object, and utilizes the fluid simulation software USim to numerically simulate the pressure, temperature, and electron density under different flight conditions, and based on the simulation results, selects the appropriate electron density and plasma collision frequency, introduces the terahertz (THz) wave, and adopts the scattering matrix method (SMM) to study the propagation characteristics of the vertically incident non-uniform magnetized plasma with the terahertz wave. Among other things, the transmission characteristics of terahertz waves in the plasma are affected by the flight altitude and flight angle of attack of the vehicle. The conclusions indicate that the transmissivity of terahertz wave transmission in plasma increases, and the reflectivity and absorptance decrease with increasing flight altitude and flight angle of attack. Under the condition of controlling other flight parameters unchanged, the plasma frequency and collision frequency decrease with the increase of flight altitude. The larger the flight angle of attack is, the larger the plasma frequency and collision frequency are. The electron density on the wall surface of the vehicle was also tested, and it was found that the lowest electron density was found at the tail end of the leeward surface. This study can provide some theoretical references for mitigating the ‘blackout’ phenomenon of re-entry vehicles.
Quantum particle under dynamical confinement: from quantum fermi acceleration to high harmonic generation
Authors: Rakhmanov S , Trunk C , Matrasulov D 
Published: May 2024

Abstract
Quantum dynamics of a particle confined in a box with time-dependent wall is revisited by considering some unexplored aspects of the problem. In particular, the case of dynamical confinement in a time-dependent box in the presence of purely time-varying external potential is treated by obtaining exact solution. Also, some external potentials approving separation of space and time variables in the Schrödinger equation with time-dependent boundary conditions are classified. Time-dependence of the average kinetic energy and average quantum force are analyzed. A model for optical high harmonic generation in the presence of dynamical confinement and external monochromatic time-dependent homogeneous electric field is proposed.
Investigating the shadows and strong gravitational lensing of modified Bardeen black holes
Authors: Molla Niyaz Uddin , Ali Amna , Debnath Ujjal , Gunasekaran Saraswathy Shamini 
Published: May 2024

Abstract
This study is dedicated to exploring the distinctive observational features affected by the modified Bardeen black hole through meticulous analysis of its shadow and strong gravitational lensing observations. We thoroughly investigated the impact of the black hole’s parameters q, g and μ on its shadow radius through numerical simulations and graphical representations. Utilizing the Event Horizon Telescope (EHT) data, we constrained the modified Bardeen black hole parameter μ of the modified Bardeen black hole within specific ranges: 0.24 ≤ μ ≤ 1.16 for M87*; and 0.036 ≤ μ ≤ 0.51 for Sgr
A
*, while maintaining the fixed values g = 0.2 and q = 0.3. This restriction of the modified Bardeen black hole parameter μ by the EHT findings illustrates the viability of modified Bardeen black holes as astrophysical candidates. Additionally, we study strong gravitational lensing and its various observables for the modified Bardeen black hole, comparing its behavior to other astrophysical black holes such as the Schwarzschild (μ = 0 = q) and Bardeen (μ = 0) black holes. By examining the astrophysical ramifications through strong gravitational lensing, considering supermassive black holes at the center of nearby galaxies, we uncovered that the modified Bardeen black hole exhibits distinct characteristics, offering a quantitative distinction from other black holes such as the Schwarzschild and Bardeen black holes. These findings in astrophysical consequences provide a promising pathway to differentiate the modified black hole from its counterparts in the realm of general relativity.