bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prior COVID‐19 infection among newly diagnosed tuberculosis patients in a tertiary care center in Tehran: A case‐control study
Authors: Semnani Kiavash , Sohrabi Marjan , Alavijeh Parvaneh Ebrahimi , SeyedAlinaghi SeyedAhmad , Esmaeili Shirin , Halabchi Farzin , Alizadeh Zahra , Salami Amir , Khaneshan Arezoo Salami 
Published: May 2024

AbstractObjectiveTo assess the risk of developing pulmonary tuberculosis (TB) in accordance with prior history of COVID‐19 infection.BackgroundSince the advent of the COVID‐19 pandemic much discussion has been had on the possible role it might play on global efforts to combat TB; most, focusing on the pandemic's impact on health care systems' capabilities to manage TB cases. Mechanisms have also been proposed by which the COVID‐19 infection may directly affect individuals' chance of developing TB infection. Cases have been reported with a history of COVID‐19 infection preceding a diagnosis of TB, evidencing its possible role as a risk factor for the disease.MethodsA case‐control study was conducted enrolling patients diagnosed with pulmonary TB in the absence of major risk factors previous history of TB, (HIV) human immunodeficiency virus infection), end‐stage renal disease, organ transplants, and use of immunosuppressive agents) for developing TB. Each patient was age and sex matched with one healthy control. Data regarding prior COVID‐19 infection, diabetes, and smoking status as well as the use of corticosteroids and Tocilizumab for the treatment of COVID‐19 infection was obtained. Bivariate analysis was conducted and variables with a likely association with TB status were entered in a multivariate model.ResultsBivariate analysis demonstrated a significant relationship between prior COVID‐19 infection and TB (95% confidence interval = 1.1−22.8, odds ratio [OR] = 5). Among other variables the severity of COVID‐19 infection was found to have a likely association with TB status (p = .125). In a multivariate model, prior COVID‐19 infection per se, was not found to be significantly associated with TB (p = .12, OR = 4.5).ConclusionsThere seems to be an association between prior history of COVID‐19 and a future diagnosis of TB partially linked to the severity of disease. The findings of the current study may serve as a basis for further studies to determine the need for and efficacy of measures to follow‐up COVID‐19 patients at an increased risk for developing TB.
Optimizing autologous stem cell collections for patients with multiple myeloma receiving G‐CSF and Plerixafor: A single center project
Authors: Javanbakht Ayda , Stringer Stephanie , Anderson Hollie , Hamilton Ellie , Philip Anisha , Waller Edmund K. , Langston Amelia A. , Joseph Nisha , Roback John D. , Schneider Thomas , Sullivan H. Cliff , Hendrickson Jeanne E. 
Published: May 2024

AbstractBackgroundIncreasing indications for cellular therapy collections have stressed our healthcare system, with autologous collections having a longer than desired wait time until apheresis collection. This quality improvement initiative was undertaken to accommodate more patients within existing resources.Study Design and MethodsPatients with multiple myeloma who underwent autologous peripheral blood stem cell collection from October 2022 to April 2023 were included. Demographic, mobilization, laboratory, and apheresis data were retrospectively collected from the medical record.ResultsThis cohort included 120 patients (49.2% male), with a median age of 60 years. All received G‐CSF and 95% received pre‐emptive Plerixafor approximately 18 hours pre‐collection. Most (79%) had collection goals of at least 8 × 106/kg CD34 cells, with 63% over 70 years old having this high collection goal (despite 20 years of institutional data showing <1% over 70 years old have a second transplant). With collection efficiencies of 55.9%, 44% of patients achieved their collection goal in a single day apheresis collection. A platelet count <150 × 103/μL on the day of collection was a predictor for poor mobilization; among 27 patients with a low baseline platelet count, 17 did not achieve the collection goal and 2 failed to collect a transplantable dose.ConclusionsWith minor collection goal adjustments, 15% of all collection appointments could have been avoided over this 6‐month period. Other strategies to accommodate more patients include mobilization modifications (Plerixafor timing or substituting a longer acting drug), utilizing platelet counts to predict mobilization, and modifying apheresis collection volumes or schedule templates.
All the menisco‐ligamentary structures of the medial plane play a significant role in controlling anterior tibial translation and tibial rotation of the knee. Cadaveric study of 29 knees with the Dyneelax® laximeter
Authors: Guegan Baptiste , Drouineau Michel , Common Harold , Robert Henri 
Published: May 2024

AbstractPurposeThis study aimed to determine the respective roles of the anterior cruciate ligament (ACL) and the different components of the medial plane in the control of anterior tibial translation and internal and external tibial rotation.MethodsTwenty‐nine fresh lower limbs, disarticulated at the hip, were tested in the anatomy laboratory. The following structures were isolated: the ACL, the anteromedial retinaculum (AMR), the medial collateral ligament (superficial and deep MCL), the posterior medial capsule (PMC) and the posterior horn of the medial meniscus (PHMM). The lower limb was positioned at 30° of flexion on the Dyneelax® laximeter (0.1 mm and 0.1° accuracies) and underwent anterior loads up to 200 N and internal and external tibial rotations sectioned from front to back. and the knee was then retested. The results were presented as relative gains in translation and rotations for each structure. Student's t test and Wilcoxon tests were used.ResultsThe relative gains in translation for the ACL, AMR, superficial MCL, deep MCL, PMC and PHMM, respectively, were 42.9%, 6.7%, 7.4%, 6%, 7.5% and 11.6%. The relative gains in internal rotation for ACL, AMR, superficial MCL, deep MCL, PMC and PHMM, respectively, were 13%, 6.9%, 4.6%, 3.9%, 13% and 8%. The relative gains in external rotation for ACL, AMR, superficial MCL, deep MCL, PMC and medial meniscus, respectively, were 8.9%, 6%, 9.7%, 13.8%,11.2% and 8.5%. All the relative gains in translation, internal and external rotations were significant at each step of transection (p < 0.01).ConclusionsThe ligamentous structures of the medial plane constitute a functional unit in which each component has a specific passive contribution. This study highlights the importance of recognising the extent of the medial ligament tears and performing a medial side anatomic and individual reconstruction and a suture of a ramp lesion, in addition to an ACL surgery.
The role of digitalization and inclusive climate in building a resilient workforce: An ability–motivation–opportunity approach
Authors: Zahoor Nadia , Roumpi Dorothea , Tarba Shlomo , Arslan Ahmad , Golgeci Ismail 
Published: May 2024

SummaryOrganizations need resilient employees to navigate and leverage constant change and maneuver in turbulent, disruptive contexts. As such, it is imperative to advance a nuanced understanding of drivers and enablers of employee resilience, especially in the current business context of pervasive digitalization and the growing practice of work‐from‐everywhere. Our research explores how digitalization in the organization is reflected in the employees' behavior of taking charge and resilience. By accounting for core self‐evaluation, digital literacy, and inclusive climate boundary conditions, we offer a holistic picture of under what conditions digitalization enhances taking charge and employee resilience. To test our study model, we follow a survey research design and rely on 173 employees' data working in the United Arab Emirates (UAE). Our results show that digitalization is positively related to employee resilience. Further, our findings show that core self‐evaluation, digital literacy, and inclusive climate moderate the impact of digitalization on employee resilience. Our results received further support in a two‐wave online survey with 306 employees in the United States. The support we found for the hypothesized mediating relationship highlights the criticality of taking charge in relation to digitalization and employee resilience. Taking charge is critical in relatively turbulent environments as it helps employees deal with changes in processes, procedures, and structures.
Relative contribution of the nail and plate to a nail‐plate construct for comminuted distal femoral fractures
Authors: Lin Charles C. , Parody Nicholas , Anil Utkarsh , Egol Kenneth A. 
Published: May 2024

AbstractThe purpose of this study was to assess the biomechanical contributions of the nail and the plate individually to a complete nail‐plate construct in the setting of comminuted distal femur fractures. For this biomechanical study, comminuted extra‐articular distal femur fractures were created in 24 synthetic osteoporotic femur models. These were then split into three groups: the nail‐only group, the plate‐only group, and the nail‐plate group. After fixation, each specimen underwent sequential axial and torsional loading, and axial and torsional stiffness were calculated and compared. The addition of a nail to a plate‐only construct increased axial stiffness by 19.7% and torsional stiffness by 59.4%. The plate‐only group and nail‐plate group both demonstrated significantly greater axial and torsional stiffness than the nail‐only group at all levels of axial and torsional load. (p < 0.001) At 1000 and 2000 N of cyclic loading, the nail‐plate group demonstrated significantly greater axial stiffness than the plate‐only group (p ≤ 0.018). The nail‐plate group demonstrated greater torsional stiffness than the plate‐only groups at all levels of torsional loading (p < 0.001). In osteoporotic comminuted distal femur fracture models, most of the axial stiffness in a nail‐plate construct comes from the plate. While the combination of the two constructs is not fully additive, the plate contributes the majority of the axial and torsional stiffness in a nail‐plate construct. The supplementation of the plate with a nail primarily helps to increase resistance to rotational forces. Level of Evidence: III.
Comparison of budesonide vehicles in inducing histologic remission in pediatric eosinophilic esophagitis
Authors: Lendner Nuphar , Minich Nori Mercuri , Malay Sindhoosha , Sferra Thomas J. , Young Denise D. 
Published: May 2024

AbstractObjectivesOral viscous budesonide (OVB) is a common medication used to treat eosinophilic esophagitis (EoE). It is typically mixed with Splenda to produce a slurry, but other delivery vehicles have been used in clinical practice. We aimed to evaluate outcomes of pediatric EoE patients treated with OVB using different drug delivery vehicles.MethodsWe performed a retrospective chart review of pediatric EoE patients treated with OVB. The primary aim was to evaluate rates of histologic remission (defined by <15 eosinophils per high power field in both mid and distal esophagus) after 6−12 weeks of OVB treatment for each delivery vehicle. Secondary aims were to evaluate histologic response and endoscopic response and remission of different delivery vehicles, and to compare the efficacy of different treatment regimens.ResultsA total of 111 patients were included in the study. Median treatment duration was 3.4 months. Overall rate of histologic remission with OVB was 52.6%. There was no difference in rates of histologic remission (p = 0.313) or response (p = 0.195 and p = 0.681 in mid and distal esophagus, respectively) among the different vehicle types or treatment regimens. Similarly, there was no difference in endoscopic remission and response among the different vehicle types (p = 0.853 and p = 0.727) or treatment regimens (p = 0.244 and p = 0.157). Patients who achieve histologic remission were more likely to be non‐Hispanic Caucasian.ConclusionOur findings suggest there is no difference in histologic and endoscopic outcomes with various delivery vehicles or combination therapy with OVB in the treatment of EoE. More palatable and cost‐effective vehicles can be used to treat EoE.
Listening to the Past, Predicting the Future: A Bibliometric Exploration of Hearing Loss Publications Over Four Decades
Authors: Aktar Uğurlu Gülay , Uğurlu Burak Numan 
Published: May 2024

ObjectivesThis article aims to analyze the scientific literature on hearing loss (HL) in the field of Otorhinolaryngology published from the past to the present.MethodsA comprehensive dataset comprising 8013 articles on HL, spanning from 1980 to 2023, was retrieved from the Web of Science database and analyzed using various statistical and bibliometric methods.ResultsThe leading countries in productivity were the United States, Japan, and Germany. The top productive journals included the International Journal of Pediatric Otorhinolaryngology (n = 652), Otology & Neurotology (579), and Acta Oto‐Laryngologica (512). The journals with the highest h‐index on hearing loss were Hearing Research (h = 65), Ear and Hearing (60), and Laryngoscope (55). Factor analysis revealed that the HL literature consisted of four constructs: main topics, speech/sound, genetics, and pharmaceutical therapies. Sudden sensorineural HL, sensorineural HL, cochlear implant, unilateral, noise‐induced and conductive HL, pediatric and age‐related HL, tinnitus, auditory brainstem response, audiometry, and prognoses for hearing health were the most researched topics from past to present. In recent years, the trending topics are genomic analysis, gene mutations, whole‐exome sequencing, genetic sequencing technique, the use of machine learning in HL, and the effect of COVID‐19 on hearing health.ConclusionThe bibliometric analysis results clearly indicate significant progress in the field of hearing loss over the past 40 years. The 8013 articles published between 1980 and 2023 encompass a wide range of research in this area. These analyses can assist in identifying priority areas and focal points for future research.Level of EvidenceNA Laryngoscope, 134:4697–4706, 2024
A Comprehensive Study of Method Optimisation of Re‐Refining Spent Lubricating Oil
Authors: Sarkar Sayantan , Datta Deepshikha , Ravindiran Gokulan , Das Bimal 
Published: May 2024

ABSTRACTUsed lubricating oil is generated by various machinery after extended operation. It is also referred to as spent mobile oil. Extremely hazardous waste lubricating oil is detrimental to the environment because it produces oxidative products when additives break down. Used lubricating oil is classified as a hazardous waste substance and has a negative impact on the environment. Polychlorinated biphenyls (PCBs), carcinogenic substances and other impurities make lubricating oil poisonous and pose a serious threat to human health and the environment. Re‐refining is considered the preferred technology for resource conservation, waste minimisation and reduced environmental hazards. The present study focuses on optimising the method of re‐refining waste lubricating oil. The effects of various operating parameters such as refining time, refining temperature, solvent‐to‐used oil ratio and flocculant dosage have been extensively studied to maximise the percentage recovery of lubricating oil. Optimum process parameters are (i) a refining time of 80 min, (ii) a refining temperature of 48°C, (iii) solvent‐to‐waste oil ratio of 5:1 (w/w) and (iv) a flocculant dosage of 2 g/kg of solvent; the optimum yield was found to be 75% with the solvent extraction method and 78% with the extraction–flocculation method, respectively. The purity and physico‐chemical properties of the recovered oil were thoroughly analysed using Fourier transform infrared spectroscopy and ASTM standard methods. It was concluded that refined oil can effectively reduce the ongoing oil crisis and create a clean, healthy environment.
Examining evidence for violence at the end of the Assyrian trading colonies period at Kaman‐Kalehöyük
Authors: Anderson Cheryl P. 
Published: May 2024

AbstractThe end of the Assyrian Trading Colonies Period (ATCP) in Anatolia represents a time of significant change in the region. Historical and archaeological evidence suggests that considerable conflict and turmoil were associated with the end of the ATCP, but thus far little evidence from human skeletal remains has been available to support this hypothesis. One of the largest human skeletal samples dating to the end of the ATCP has been excavated at Kaman‐Kalehöyük in central Anatolia. A minimum of 73 individuals have been found in and around areas of the site that have signs of destruction and burning. These individuals appear to be associated with a battle that occurred in the town in the mid‐18th century BCE. The results show that the victims of the battle included individuals of all age groups and both sexes. The degree of burning and fragmentation made the identification of perimortem trauma challenging; however, perimortem trauma was observed in at least two individuals. An additional five individuals had evidence of antemortem trauma that was likely the result of interpersonal violence prior to the attack on the town. The skeletal evidence for trauma further supports the idea that a battle occurred at the site. This battle may have also been a part of a regional pattern of violence corresponding with the end of the ATCP, as suggested by the textual and archaeological evidence.
Exploring height outcomes with adjuvant aromatase inhibition in growth hormone–deficient male survivors of childhood cancer
Authors: Pollock Netanya I. , Song Minkeun , Wolf Alexander J. , Li Yimei , Hawkes Colin P. , Motamedi Niloofaralsadat , Denburg Michelle R. , Mostoufi‐Moab Sogol 
Published: May 2024

AbstractBackgroundAromatase inhibitors (AI) may improve height in short stature conditions; however, the effect in childhood cancer survivors (CCS) is unknown. We assessed final adult height (FAH) in CCS treated with AI and GH compared with those treated with GH alone.MethodsRetrospective cohort study of GH‐deficient male CCS treated between 2007 and 2023. FAH was noted as the height at the fusion of growth plates or 18 years of age. Multivariable linear regression was used to examine treatment association with FAH, adjusting for other risk factors.ResultsNinety‐two patients were included; 70 were treated with GH and 22 with combination AI/GH. The mean age at GH initiation did not differ between groups. The mean age at AI initiation was 13.7 ± 1.9 years. A greater proportion of patients in the AI/GH group were treated with stem cell transplantation, abdominal radiation, total body irradiation, and cis‐retinoic acid (p < .01). Multivariable linear regression demonstrated no significant treatment association with FAH Z‐score (β = 0.04, 95% CI: −0.9 to 0.9). History of spinal radiation (β = −0.93, 95% CI: −1.7 to −0.2), lower starting height Z‐score (β = −0.8, 95% CI: −1.2 to −0.4), and greater difference between bone age and chronological age (β = −0.3, 95% CI: −0.5 to −0.07) were associated with lower FAH Z‐score.ConclusionsAdjuvant AI was not associated with increased FAH in male CCS compared with GH monotherapy. Future work is needed to determine the optimal adjunctive treatment to maximize FAH for this population.
Auf Tuchfühlung mit der Sonne
Authors: Bothmer Volker 
Published: May 2024

ZusammenfassungAm 28. April 2021 um 09:33 UT hat die Parker Solar Probe als erste Raumsonde überhaupt die Sonnenkorona direkt durchflogen. Der Abstand betrug nur 18 Millionen Kilometer zur Sonnenoberfläche. Dies ist der Menschheit erster Besuch einer Sternatmosphäre. Unser Verständnis der magnetischen Prozesse auf der Sonne und in der Sonnenkorona sowie ihrer Auswirkungen auf den Weltraum haben ein völlig neues Bild ergeben: Die Korona und der sonnennahe Raum sind ein Medium, das von turbulenten Sonnenwindströmen und von der Sonne aus expandierenden Magnetfeldern ausgefüllt wird. Dies steht im Gegensatz zur bisherigen Vorstellung einer statischen Korona, die von gelegentlichen Sonneneruptionen überlagert wird.
Tiefer Einblick ins innere Sonnensystem
Authors: Bothmer Volker 
Published: May 2024

ZusammenfassungDie Parker Solar Probe‐Mission hat einzigartige neue Beobachtungen der Staubverteilungen im inneren Sonnensystem und in den Planeten‐ und Asteroidenbahnen von Venus und Phaeton 3200 ermöglicht. Zum ersten Mal konnte die bisher nur theoretisch postulierte Existenz einer staubfreien Zone nahe der Sonne direkt optisch bestätigt werden. Aufnahmen der WISPR‐Kamera zeigten erstmals die Oberfläche der Venus im sichtbaren, dem Infraroten nahen Spektralbereich. Auch die Bahn des Staubschweifs des Asteroiden Phaeton konnte sie aufnehmen. Das erlaubt wichtige Rückschlüsse auf die mineralogische Zusammensetzung der Venusoberfläche sowie eine Datierung des Ursprungs des Geminiden‐Meteoritenschauers durch eine kosmische Kollision vor etwa 2000 bis 3000 Jahren.
Sexual satisfaction and its predictors in patients with advanced cancer and their family caregivers in six European countries: Baseline data from the DIAdIC study
Authors: Matthys Orphé , Dierickx Sigrid , Van Goethem Vincent , Deliens Luc , Lapeire Lore , De Pauw Aglaja , Hudson Peter , Vulsteke Christof , Geboes Karen , De Waele Stefanie , Spoormans Isabelle , Di Leo Silvia , Guberti Monica , Schmidt Ulrik Sørensen , Scott David , Harding Richard , Witkamp Erica , Connolly Michael ,   DIAdIC team, De Vleminck Aline , Cohen Joachim 
Published: May 2024

AbstractObjectiveTo identify predictors of sexual satisfaction in patients with advanced cancer and their family caregivers.MethodsCross‐sectional study using baseline survey data from a randomized controlled trial in six European countries. Patients with advanced cancer and their family caregiver completed measures on sexual satisfaction (one item from Functional Assessment of Cancer Therapy ‐ General questionnaire for patients and Caregiver Quality of Life Index‐Cancer scale for family caregivers) and health‐related characteristics. Multivariable linear regressions were performed for all predictors (identified based on literature) with sexual satisfaction as dependent variable.ResultsThe sample comprised 431 patient‐family caregiver dyads. Patients with prostate or gynecological cancer reported lower sexual satisfaction (respectively B = −0.267 95% CI: −1.674, −0.594 and B = −0.196, 95% CI −2.103, −0.452). Higher emotional (B = 0.278, 95% CI 0.024, 0.057) physical (B = 0.305, 95% CI 0.012, 0.025) and social functioning (B = 0.151, 95% CI 0.001, 0.013), global health (B = 0.356, 95% CI 0.007, 0.013) and social wellbeing (B = 0.161, 95% CI 0.013, 0.082) among patients were associated with higher sexual satisfaction. Among family caregivers, sexual satisfaction was lower with increased age (B = −0.142, 95% CI −0.022, −0.004). Higher emotional functioning (B = 0.027, 95% CI 0.011, 0.043) and quality of life (B = 0.165, 95% CI −0.165, 0.716) were associated with higher sexual satisfaction in family caregivers.ConclusionsThe results underscore that sexual wellbeing of patients and family caregivers is related to health related factors in physical, emotional, and social domains. Patients and family caregivers could benefit from a dyadic approach to address sexual wellbeing.