bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Generic Platform for the Addressable Functionalisation of Electrode Surfaces through Self‐Induced “Electroclick”
Authors: Orain Christophe , Le Poul Nicolas , Gomila Antoine , Kerbaol Jean‐Michel , Cosquer Nathalie , Reinaud Olivia , Conan Françoise , Le Mest Yves 
Published: December 2011

AbstractA novel and general strategy for the immobilisation of functional objects onto electrodes is described. The concept is based on the addition of two pendant ethynyl groups onto a bis(pyridyl)amine derivative, which acts as a molecular platform. This platform is pre‐functionalised with an N3‐tagged object of interest by Huisgen cycloaddition to one of the ethynyl groups in biphasic conditions. Hence, when complexed by CuII, this molecular‐object holder can be immobilised, by a “self‐induced electroclick”, through the second ethynyl group onto N3‐alkanethiol self‐assembled monolayers on a gold electrode. Two different functional groups, a redox innocent ((CH2)3Ph) and an electrochemical probe (ferrocene), were immobilised by following this strategy. The in situ electrochemical grafting showed, for both systems, that the kinetics of immobilisation is fast. The voltammetric characterisation of the surface‐tagged functionalised copper complexes indicated that a good surface coverage was achieved and that a moderately fast electron‐transfer reaction occurs. Remarkably, in the case of the redox‐active ferrocenyl‐immobilised system, the electrochemical response highlighted the involvement of the copper ion of the platform in the kinetics of the electron transfer to the ferrocene moiety. This platform is a promising candidate for applications in surface addressing in areas as diverse as biology and materials.
Current Chemical Biology Tools for Studying Protein Phosphorylation and Dephosphorylation
Authors: H. S. Lu Candy , Liu Kai , Tan Lay Pheng , Yao Shao Q. 
Published: December 2011

AbstractAmongst different posttranslational events involved in cellular‐signaling pathways, phosphorylation and dephosphorylation of proteins are the most prevalent. Aberrant regulations in the cellular phosphoproteome network are implicated in most major human diseases. Consequently, kinases and phosphatases are two of the most important groups of drug targets in medicinal research today. A major challenge in the understanding of protein phosphorylation and dephosphorylation is the sheer complexity of the phosphoproteome network and the lack of tools capable of studying protein phosphorylation and dephosphorylation as they occur in cells. We highlight herein various chemical biology tools that have emerged in the last decade for such studies. First, we discuss the use of small‐molecule mimics of phosphoamino acids and their use in elucidating the function of protein phosphorylation and dephosphorylation. We also introduce recent advances in the field of activity‐based protein profiling (ABPP) for proteome‐wide detection of protein phosphorylation and dephosphorylation. We next discuss the key concepts in the design of peptide‐ and protein‐based biosensors capable of real‐time reporting of phosphorylation/dephosphorylation events. Finally, we highlight the application of peptide and small‐molecule microarrays (SMMs), and their applications in high‐throughput screening and discovery of new compounds related to phosphorylation/dephosphorylation.
ChemInform Abstract: Anomalous Thermal Expansion in the Square‐Net Compounds RE4TGe8 (RE: Yb, Gd; T: Cr—Ni, Ag).
Authors: Peter Sebastian C. , Chondroudi Maria , Malliakas Christos D. , Balasubramanian Mahalingam , Kanatzidis Mercouri G. 
Published: December 2011

AbstractYb4Ag0.56Ge8 (I), Yb4Co1.17Ge8 (II), Yb4Cr1.07Ge8 (III), Yb4Cr1.04Ge8 (IV), Yb4Fe1.10Ge8 (V), Yb4Mn1.00Ge8 (VI), Yb4Ni1.12Ge8 (VII), and Gd4Cr1.33Ge8 (VIII) are synthesized from the elements (850 °C, 144 h) and characterized by XRD, XANES, and DFT band structure calculations.
ChemInform Abstract: Cs4UGe8O20: A Tetravalent Uranium Germanate Containing Four‐ and Five‐Coordinate Germanium.
Authors: Nguyen Quang Bac , Lii Kwang‐Hwa 
Published: December 2011

AbstractThe title compound is synthesized from a mixture of CsF, CsI, UO3, Al, and GeO2 in (gold ampule, autoclave, 160 MPa, 585 °C, 2 d).
ChemInform Abstract: Ba4KFe3O9: A Novel Ferrite Containing Discrete 6‐Membered Rings of Corner‐Sharing FeO4 Tetrahedra.
Authors: zur Loye Hans‐Conrad , et al. et al. 
Published: December 2011

AbstractSingle crystals of the new title compound are prepared from a mixture of Ba(OH)2, KOH, and Fe2O3 (alumina crucible, 750 °C, 5 h).
ChemInform Abstract: Introducing a Magnetic Guest to a Tetrel‐Free Clathrate: Synthesis, Structure, and Properties of EuxBa8‐xCu16P30 (0 ≤ x ≤ 1.5).
Authors: Kovnir Kirill , Stockert Ulrike , Budnyk Sergij , Prots Yurii , Baitinger Michael , Paschen Silke , Shevelkov Andrei V. , Grin Yuri 
Published: December 2011

AbstractThe title compounds are prepared by solid state reactions of the elements (1125 K, 360 h) and characterized by powder and single crystal XRD, XAS, electrical resistivity, specific heat, and magnetic susceptibility measurements.
ChemInform Abstract: Undulating Layers in a New Rhodate Network: Structure of Bi1.4CuORh5O10.
Authors: Mizoguchi Hiroshi , Michiue Yuichi , Sleight Arthur W. , Subramanian M. A. 
Published: December 2011

AbstractThe new title compound is prepared from a mixture of CuO and Rh2O3 in a Bi2O3/V2O5 (3:1) flux (Pt crucible, 1373 K, 10 h).
ChemInform Abstract: Synthesis of Novel 1,4‐Bissulfonamide Ligands for Enantioselective Addition of Diethylzinc to Aldehydes.
Authors: Yang Minghua , Sun Jiangtao , Zhu Chengjian 
Published: December 2011

AbstractSeveral chiral sulfonamides ligands are synthesized and screened for their catalytic activity in the enantioselective addition of diethylzinc to aldehydes.
ChemInform Abstract: Design of Silver(I)‐Heteropolyacids: Toward the Molecular Control of Reactivity in Organic Chemistry.
Authors: Borghese Sophie , Louis Benoit , Blanc Aurelien , Pale Patrick 
Published: December 2011

AbstractBy tuning the amount of silver and the acidity, a bifunctional polyoxymetalate is designed exhibiting both metallic properties and Broensted acidity.
ChemInform Abstract: AlBr3·6H2O Catalyzed Oxidation of Benzylic Alcohols.
Authors: Zhong Yun‐Mei , Ma Heng‐Chang , Wang Jin‐Xia , Jia Xiao‐Jie , Li Wen‐Feng , Lei Zi‐Qiang 
Published: December 2011

AbstractPrimary and secondary benzylic alcohols are transformed into the corresponding aldehydes and ketones with almost complete conversion and high selectivity.
ChemInform Abstract: Synthesis of N‐Acyl‐N,O‐acetals from N‐Aryl Amides and Acetals in the Presence of TMSOTf.
Authors: Downey C. Wade , Fleisher Alan S. , Rague James T. , Safran Chelsea L. , Venable Megan E. , Pike Robert D. 
Published: December 2011

AbstractIt is demonstrated, that TmsOTf mediates the one‐pot reactions shown.
ChemInform Abstract: Improved Ruthenium‐Catalyzed Amination of Alcohols with Ammonia: Synthesis of Diamines and Amino Esters.
Authors: Imm Sebastian , Baehn Sebastian , Zhang Min , Neubert Lorenz , Neumann Helfried , Klasovsky Florian , Pfeffer Jan , Haas Thomas , Beller Matthias 
Published: December 2011

AbstractThe homogeneous selective catalytic diamination of primary and secondary diols with ammonia gives the corresponding diamines in high yields.
ChemInform Abstract: Recyclable Catalysts for Palladium‐Catalyzed Aminations of Aryl Halides.
Authors: Dumrath Andreas , Luebbe Christa , Neumann Helfried , Jackstell Ralf , Beller Matthias 
Published: December 2011

AbstractAt low catalyst loadings of Pd(OAc)2 (0.25‐2.0 mol%) with PMI as ligand, aryl/heteroaryl chlorides or bromides are efficiently aminated by ammonia or primary and secondary amines.
ChemInform Abstract: Titanocene(III) Chloride Mediated Radical Induced Allylation of Aldimines: Formal Synthesis of C‐Linked 4′‐Deoxy Aza‐disaccharide.
Authors: Saha Sumit , Roy Subhas Chandra 
Published: December 2011

AbstractThe reaction allows a mild and convenient access to homoallyl amines as useful synthons.
ChemInform Abstract: anti‐Markovnikov Hydroalkylation of Allylic Amine Derivatives via a Palladium‐Catalyzed Reductive Cross‐Coupling Reaction.
Authors: DeLuca Ryan J. , Sigman Matthew S. 
Published: December 2011

AbstractPalladium‐catalyzed hydroalkylation of allylic amines with alkylzinc reagents proceeds with high to excellent chemoselectivity in favor of anti‐Markovnikov products in most cases (linear‐to‐branched ratio from 8:1 up to <20:1).
ChemInform Abstract: Nickel‐Catalyzed C—H Arylation of Azoles with Haloarenes: Scope, Mechanism, and Applications to the Synthesis of Bioactive Molecules.
Authors: Yamamoto Takuya , Muto Kei , Komiyama Masato , Canivet Jerome , Yamaguchi Junichiro , Itami Kenichiro 
Published: December 2011

AbstractNovel nickel‐based catalytic systems are developed for the arylation of a variety of N‐heterocycles with aryl/heteroaryl chlorides, bromides, iodides, and a triflate.
ChemInform Abstract: Ruthenium‐Catalyzed Ring‐Closing Metathesis Accelerated by Long‐Range Steric Effect.
Authors: Fujihara Tetsuaki , Tomike Yoshikazu , Ohtake Toshiyuki , Terao Jun , Tsuji Yasushi 
Published: December 2011

AbstractTwo highly active ruthenium‐based metathesis catalysts with N‐heterocyclic carbene ligands bearing 2,3,4,5‐tetraarylphenyl moieties are developed.
ChemInform Abstract: Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design.
Authors: Sparr Christof , Gilmour Ryan 
Published: December 2011

AbstractAn unprecedented strategy for the enantioselective synthesis of 1,3‐dichlorides of type (II) and (IV) uses the ring opening of cyclopropylaldehydes under conditions A).
ChemInform Abstract: γ‐Selective Cross‐Coupling of Allylic Silanolate Salts with Aromatic Bromides Using Trialkylphosphonium Tetrafluoroborate Salts Prepared Directly from Phosphine·Borane Adducts.
Authors: Denmark Scott E. , Werner Nathan S. 
Published: December 2011

AbstractThe (Z) geometry of the silanolate (I) increases the γ‐selectivity to 99:1 except in the case of quinoline derivative (IV).
ChemInform Abstract: Simple, Stable, and Easily Accessible Well‐Defined CuCF3 Aromatic Trifluoromethylating Agents.
Authors: Tomashenko Olesya A. , Escudero‐Adan Eduardo C. , Martinez Belmonte Marta , Grushin Vladimir V. 
Published: December 2011

AbstractTrifluoromethylation of various aryl iodides is achieved using two new Cu(I) trifluoromethylating agents (I) and (IV).
ChemInform Abstract: A Highly Versatile Catalytic System for N‐Arylation of Amines with Aryl Chlorides in Water.
Authors: Huang Manna , Lin Xiaoqin , Zhu Xinhai , Peng Weili , Xie Jianwei , Wan Yiqian 
Published: December 2011

AbstractA novel efficient catalyst system is presented for the C—N coupling of various aryl chlorides (II) with a diversity of amines, including aniline (I), benzylamine (IV), N‐heterocycles like imidazole (VI) as well as ammonia, in aqueous solution.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Umpolung of Michael Acceptors for Intermolecular Reactions.
Authors: Biju Akkattu T. , Padmanaban Mohan , Wurz Nathalie E. , Glorius Frank 
Published: December 2011

AbstractThe transition‐metal free transformation of Baylis—Hillman products results in stereoselective formation of homocoupling products (II)/(III).
ChemInform Abstract: The Ugi Reaction in a Polyethylene Glycol Medium: A Mild, Protocol for the Production of Compound Libraries.
Authors: Niu Teng‐fei , Lu Guo‐ping , Cai Chun 
Published: December 2011

AbstractAn efficient, mild und eco‐friendly method for the Ugi reaction in PEG‐water is described.
ChemInform Abstract: Applications of a Monomeric Orthopalladate Complex Containing Mixed Phosphorus—Nitrogen Donors in the Heck Reaction.
Authors: Hajipour Abdol Reza , Rafiee Fatemeh , Rouho Arnold E. 
Published: December 2011

AbstractIt is demonstrated that the thermally stable and oxygen‐insensitive PNB is highly efficient in a broad spectrum concerning reactions of olefins with aryl halides and sulfonyl chlorides.
ChemInform Abstract: Methylenecyclopropane as C1 Synthetic Units: [1 + 4] Cycloaddition via a Nickel Catalyst.
Authors: Inami Tasuku , Kurahashi Takuya , Matsubara Seijiro 
Published: December 2011

AbstractNi‐catalyzed reactions of methylenecyclopropanes (I) with thiophthalic anhydrides afford highly substituted thiophthalides in good yields.
ChemInform Abstract: Oxidative Intramolecular Bromo‐Amination of N‐Alkenyl Sulfonamides via Umpolung of Alkali Metal Bromides.
Authors: Moriyama Katsuhiko , Izumisawa Yuta , Togo Hideo 
Published: December 2011

AbstractThe method provides a new and efficient approach to a number of 2‐(bromomethly)pyrrolidine and indole derivatives.
ChemInform Abstract: Chiral Sulfonimide as a Broensted Acid Organocatalyst for Asymmetric Friedel—Crafts Alkylation of Indoles with Imines.
Authors: Chen Ling‐Yan , He Hao , Chan Wing‐Hong , Lee Albert W. M. 
Published: December 2011

AbstractThe chiral sulfonimide efficiently promotes the process.
ChemInform Abstract: Palladium‐Catalyzed Synthesis of 7,9‐Diaryl‐8H‐acenaphtho[1,2‐c]pyrroles and Their Application in Explosives Detection.
Authors: Chen Xiaopeng , Jin Jisong , Wang Yanguang , Lu Ping 
Published: December 2011

AbstractBis(arylethynyl)naphthalenes and primary amines undergo a highly atom‐efficient bicyclization under air to give the fused pyrroles which exhibit fluorescence around 450 nm.
ChemInform Abstract: Stereoselective Nickel‐Catalyzed [2 + 2 + 2] Cycloaddition of Enynes and Arynes.
Authors: Candito David A. , Lautens Mark 
Published: December 2011

AbstractIf a substituent is present adjacent to the olefin moiety, a good to excellent trans‐selectivity in product formation is observed.
ChemInform Abstract: Synthesis of N1‐3‐{(4‐Substituted aryl‐3‐chloro‐2‐oxo‐azetidine)‐iminocarbamyl}‐propyl‐6‐nitroindazole Derivatives and Their Biological Significance.
Authors: Samadhiya Pushkal , Sharma Ritu , Srivastava Santosh K. , Srivastava Savitri D. 
Published: December 2011

AbstractNew title indazole derivatives (VII) (19 examples) are synthesized and evaluated for their antimicrobial and antitubercular activities.
ChemInform Abstract: Synthesis and Conformational Features of 4‐(Cyclohexylsulfanyl)‐1‐(2,4‐dinitrophenyl)‐3‐aryl‐1H‐pyrazole.
Authors: Manikannan Ramaiyan , Venkatesan Ramaiyan , Muthusubramanian Shanmugam 
Published: December 2011

AbstractThe reaction can also be conducted under conventional heating conditions at 80°C giving slightly lower yields of the desired products.
ChemInform Abstract: Efficient Multi‐Component Synthesis of Highly Substituted Imidazoles Utilizing P2O5/SiO2 as a Reusable Catalyst.
Authors: Shaterian Hamid Reza , Ranjbar Mohammad , Azizi Kobra 
Published: December 2011

AbstractA variety of 2,4,5‐ trisubstituted imidazoles (III) (31 examples) and 1,2,4,5‐tetrasubstituted imidazoles (VI) (40 examples) is prepared via multicomponent reactions under thermal solvent‐free conditions using P2O5—SiO2 as efficient and reusable catalyst.
ChemInform Abstract: Synthesis and Cytotoxicity of Novel 2‐Amino‐5‐thiazolecarboxamide Derivatives.
Authors: Li Hu , Yue Yun , Hu Xiao‐Jun , Zhao Sheng‐Yin 
Published: December 2011

AbstractSome of the title compounds show moderate cytotoxicity against HL‐60 and K562 cell lines.
ChemInform Abstract: ClickEnam. Part 1. Synthesis of Novel 1,4‐Disubstituted‐[1,2,3]‐triazole‐derived β‐Aminovinyl Trifluoromethylated Ketones and Their Copper(II) Complexes.
Authors: Chopin Nicolas , Decamps Sophie , Gouger Aude , Medebielle Maurice , Picot Stephane , Bienvenu Anne‐Lise , Pilet Guillaume 
Published: December 2011

AbstractThe synthesized compounds are screened as potential antifungal agents.
ChemInform Abstract: An Unexpected Synthesis of 3,5‐Diaryl‐1,2,4‐thiadiazoles from Thiobenzamides and Methyl Bromocyanoacetate.
Authors: Mayhoub Abdelrahman S. , Kiselev Evgeny , Cushman Mark 
Published: December 2011

AbstractAttempted synthesis of thiazole‐5‐carboxylates (III) as potential antiviral agents from ester (II) and arylthiobenzamides results in an unexpected formation of the pseudo‐dimeric 1,2,4‐thiadiazoles (IV), where compound (II) acts only as mediator.
ChemInform Abstract: Lewis Acid Promoted Benzylic Cross‐Couplings of Pyridines with Aryl Bromides.
Authors: Duez Stephanie , Steib Andreas K. , Manolikakes Sophia M. , Knochel Paul 
Published: December 2011

AbstractSeveral Lewis acids such as ZnCl(TMP) or BF3·OEt2 are used to promote the palladium‐catalyzed arylations of various methylpyridines.
ChemInform Abstract: MgO Nanoparticles as a Recyclable Heterogeneous Catalyst for the Synthesis of Polyhydroquinoline Derivatives under Solvent‐Free Conditions.
Authors: Ranjbar‐Karimi Reza , Hashemi‐Uderji Somayeh , Bazmandegan‐Shamili Alireza 
Published: December 2011

AbstractThe employed catalyst can be reused several times without significant loss of activity.
ChemInform Abstract: Synthesis of 7‐Aryl‐1,8‐naphthyridines via Addition of Aryl Boronic Acids to 1,8‐Naphthyridine N‐Oxides.
Authors: Bennie Linsey S. , Burton Paul M. , Morris James A. 
Published: December 2011

AbstractThe method is not sensitive to moisture or air and can be extended to other electron‐deficient N‐oxides [cf.
ChemInform Abstract: Novel Synthetic Azaacridine Analogues as Topoisomerase 1 Inhibitors.
Authors: Luan Xudong , Gao Chunmei , Sun Qinsheng , Tan Chunyan , Liu Hongxia , Jin Yibao , Jiang Yuyang 
Published: December 2011

AbstractThe compound (IV) (no yield given) shows good cytotoxicity against K562 and HepG‐2, interacts with calf thymus DNA and inhibits topoisomerase 1 activity.
ChemInform Abstract: Condensed Isoquinolines. Part 37. Heterocyclization Using 3‐(Arylamino)‐ and 3‐(Hetarylamino)isoquinolin‐1(2H)‐ones.
Authors: Potikha L. M. , Gutsul R. M. , Plaskon A. S. , Kovtunenko V. A. , Tolmachev A. A. 
Published: December 2011

AbstractThe reaction of 3‐aminoisoquinolinone derivatives with aromatic aldehydes in the presence of Tms‐Cl leads to the formation of fused naphthyridine and isoquinolinone derivatives.
ChemInform Abstract: Eco‐Friendly and Efficient Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones
Authors: Majid Ghashang , Kobra Aziz , Hamed Moulavi‐Pordanjani , Hamid Reza Shaterian 
Published: December 2011

Abstractvia one‐pot three‐component cyclocondensation of isotoic anhydride (I) with aldehydes and N‐sources or condensation of anthranilamide with aldehydes
ChemInform Abstract: Palladium‐Catalyzed Intramolecular C(sp2)—H Amidination by Isonitrile Insertion Provides Direct Access to 4‐Aminoquinazolines from N‐Arylamidines.
Authors: Wang Yong , Wang Honggen , Peng Jiangling , Zhu Qiang 
Published: December 2011

AbstractSterically hindered groups are inserted at the C4‐position of the quinazoline ring, which is an important scaffold of many biological materials.
ChemInform Abstract: Substituted 2‐Aminonicotinamides in the Synthesis of Pyrido[2,3‐d]pyrimidin‐4(1H)‐ones, 2,3‐Dihydropyrido[2,3‐d]pyrimidin‐4(1H)‐ones, and 11b,12‐Dihydropyrido[2′,3′:4,5]pyrimido[2,1‐a]isoindole‐5,7‐diones.
Authors: Sidorova E. A. , Kostenko E. S. , Arustamova I. S. , Kaigorodova E. A. , Konyushkin L. D. 
Published: December 2011

AbstractTitle compounds (III), (V), (VII), and (IX) are synthesized starting from aminonicotinamides (I) according to [NC3N + C] cyclization scheme.
ChemInform Abstract: Rapid Access to 1‐Benzyl 2‐Substituted Piperazines: Application to the Synthesis of 1‐Benzyl‐2‐difluoromethyl‐piperazine.
Authors: Napolitano Carmela , Borriello Manuela , Cardullo Francesca , Donati Daniele , Paio Alfredo , Manfredini Stefano 
Published: December 2011

AbstractAn efficient route to title compound (VI) is presented.
ChemInform Abstract: Silyl Fluoride Electrophiles for the Enantioselective Synthesis of Silylated Pyrrolidine Catalysts.
Authors: Jentzsch Kaleb I. , Min Taewoo , Etcheson Jennifer I. , Fettinger James C. , Franz Annaliese K. 
Published: December 2011

Abstract(‐)‐Sparteine‐mediated treatment of the pyrrole (I) with the silyl fluorides (II) allows efficient and highly stereoselective access to the products (III).
ChemInform Abstract: BF3·SiO2‐Catalyzed One‐Pot Synthesis of α‐Aminophosphonates in Ionic Liquid and Neat Conditions.
Authors: Reddy Mudumala Veeranarayana , Dindulkar Someshwar D. , Jeong Yeon Tae 
Published: December 2011

AbstractOptimized conditions are developed for the three‐component condensation to give the title compounds in a short reaction time.
ChemInform Abstract: A Facile Cu(I)/TF‐BiphamPhos‐Catalyzed Asymmetric Approach to Unnatural α‐Amino Acid Derivatives Containing gem‐Bisphosphonates.
Authors: Xue Zhi‐Yong , Li Qing‐Hua , Tao Hai‐Yan , Wang Chun‐Jiang 
Published: December 2011

AbstractAsymmetric Michael addition of azomethine ylide (II) towards gem‐bisphosphonyl alkenes (I), (IX) and (XI) in the presence of a chiral Cu(I)—BiphamPhos complex provides access to a variety of novel non‐natural α‐amino acids bearing a gem‐bisphosphonate structural unit (III), (X), and (XII), respectively.
ChemInform Abstract: Nickel‐Catalyzed C—P Cross‐Coupling by C—CN Bond Cleavage.
Authors: Sun Meng , Zhang Hong‐Yu , Han Qi , Yang Kuo , Yang Shang‐Dong 
Published: December 2011

AbstractUnder optimized conditions, a wide variety of aryl/heteroaryldiphenylphosphanes is prepared including potential P,N‐bidentate ligands using Me3SiPPh2 as phosphorus source.
ChemInform Abstract: Tareciliosides H—M: Further Cycloartane Glycosides from Leaves of Tarenna gracilipes.
Authors: Zhao Zhimin , Matsunami Katsuyoshi , Otsuka Hideaki , Shinzato Takakazu , Takeda Yoshio 
Published: December 2011

AbstractThe new compounds, tarecilioside H (Ia), I (Ib), J (IIa), K (IIb), L (III), and M (IV), are further cycloartane glycosides from the extract of the title plant.
ChemInform Abstract: Synthesis of Pregnane 3‐Carboxylic Acids via Pd‐Catalyzed Alkoxycarbonylation and Their Effect on NMDA Receptor Activity.
Authors: Stastna Eva , Chodounska Hana , Pouzar Vladimir , Borovska Jirina , Vyklicky Ladislav Jr. 
Published: December 2011

AbstractIt is found that the 5β‐carboxylic acid derivatives diminish NMDA‐ induced responses, whereas the 5α‐derivative potentiate the response.
ChemInform Abstract: Electrochemically Generated ArS(ArSSAr)+B(C6F5)4‐ as an Activator of Thioglycosides for Glycosylation.
Authors: Saito Kodai , Saigusa Yoshihiro , Nokami Toshiki , Yoshida Jun‐ichi 
Published: December 2011

AbstractThe efficiency of the activator in the title reaction depends on the nature of the counter anion.
ChemInform Abstract: Synthesis of a Complete Janus‐Type Guanosine—Cytosine Base and Its 2′‐Deoxyribonucleoside.
Authors: Zhao Hang , Huang Wen , Wu Xiaohua , Qing Yong , Xing Zhihua , He Yang 
Published: December 2011

AbstractA viable synthetic route for the synthesis of the complete Janus‐type guanosine‐cytosine base (VI) and its derivative (IX) is presented.
ChemInform Abstract: Exploration of L‐Proline‐Catalyzed α‐Aminoxylation of Aldehyde to (S)‐Guaifenesin‐Related Drug Molecules.
Authors: Panchgalle Sharad P. , Kunte Sunita S. , Chavan Subhash P. , Kalkote Uttam R. 
Published: December 2011

AbstractThe title reaction leads to enantiomerically pure guaifenesin (II) which is used for the preparation of (S)‐(‐)‐moprolol (V) and (R)‐(+)‐methocarbamol (VIII).
ChemInform Abstract: New Prenylated C6—C3 Compounds from the Twigs of Illicium anisatum.
Authors: Kubo Miwa , Shima Naoki , Harada Kenichi , Hioki Hideaki , Fukuyama Yoshiyasu 
Published: December 2011

AbstractThe new compound (I), named cycloillicinone, is isolated together with the new compound (II) which shows moderate neurite‐outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 μM.
ChemInform Abstract: A Novel Macrocyclic Lactone with Insecticidal Bioactivity from Streptomyces microflavus neau3.
Authors: Wang Xiang‐Jing , Zhang Ji , Liu Chong‐Xi , Gong Dian‐Liang , Zhang Hui , Wang Ji‐Dong , Yan Yi‐Jun , Xiang Wen‐Sheng 
Published: December 2011

AbstractLactone (I), isolated from the fermentation broth of S.microflavus neau3, displays lower acaricidal potency against adult mites and nematocidal activity against C.elegans than the positive control, but shows higher acaricidal activity against mite eggs.