bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of empathy on professional identity among Chinese junior male nurses: a moderated mediation model
Authors: Mu Hezi , Cui Yi , Zhang Lihua , Liu Qin , Zhang Lanfang , Yang Haoshuang , Chen Changchang , Liu Na , Zhang Yinling 
Published: February 2025

BackgroundNursing care is essential, but the role of junior male nurses in medical and health services is underestimated; thus, many junior male nurses leave the profession due to a lack of professional identity.ObjectiveThis study examined how the mediating effect of emotional intelligence and the moderating role of locomotion mode influence the relationship between empathy and professional identity among Chinese junior male nurses.MethodsThis cross-sectional descriptive study was conducted among junior male nurses in China from December 2021 to May 2022. We asked participants from ten hospitals to complete a questionnaire regarding empathy, emotional intelligence, locomotion mode, and professional identity. Bootstrap and simple slope methods were used to test the moderated mediation model.ResultsEmotional intelligence partly mediated the effects of perspective-taking on professional identity (β = 0.253, p &lt; 0.05). Furthermore, locomotion mode moderated the relationships between perspective-taking and emotional intelligence, perspective-taking and professional identity, and emotional intelligence and professional identity (β = 0.136, p &lt; 0.01; β = 0.107, p &lt; 0.05; β = −0.155, p &lt; 0.01).ConclusionThe findings revealed that,the mediating effect of emotional intelligence on the relation between perspective-taking and professional adaptability was moderated by locomotion mode. Whereas. These findings are meaningful for early intervention and the improvement of professional identity among junior male nurses.
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study
Authors: Kridin Khalaf , Papara Cristian , Bieber Katja , De Luca David A. , Klein Jan Philipp , Ludwig Marlene A. , Curman Philip , Vorobyev Artem , Dempfle Astrid , Ludwig Ralf J. 
Published: February 2025

IntroductionChronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. Thus, they are a major medical burden with a high unmet need. CIDs develop over the span of several years, and the risk of developing CIDs has been linked to genetic and environmental factors. Thus, modification of environmental factors is a promising approach for the prevention of CIDs. Among modifiable environmental factors that have been linked to the CID risk is nicotine dependence. However, for only few CIDs, compelling evidence suggests that nicotine dependence increases (e.g., rheumatoid arthritis and asthma) or decreases (e.g., pemphigus) the CID risk. For most CIDs, there are inconsistent, scant, or no reports on the risk of CID associated with nicotine dependence.MethodsTo address this gap, we leveraged TriNetX, analyzing data from over 120 million electronic health records (EHRs). Using propensity score matching (PSM) to control for age, sex, ethnicity, and other CID risk factors, we contrasted the risk of developing any or any of the 38 CIDs in 881,192 EHRs from individuals with nicotine dependence to PSM-matched unexposed counterparts.ResultsThe analytical pipeline was validated by demonstrating an increased risk of individuals exposed to nicotine dependence for subsequent diagnosis of myocardial infarction, malignant neoplasm of the lung, and chronic obstructive pulmonary disease. Overall, 16.8% of individuals with nicotine dependence developed CIDs, compared to 9.6% of individuals not exposed to nicotine dependence (hazard ratio 2.12, confidence interval 2.10–2.14, p &lt; 0.0001). Investigating single CIDs, nicotine dependence imposed increased risks for 23 of the 38 investigated diseases, i.e., dermatomyositis, granulomatosis with polyangiitis, pyoderma gangrenosum, and immune thrombocytopenic purpura. The sex-stratified analysis revealed few sex-specific differences in CID risk.DiscussionOur study emphasizes the importance of preventive measures targeting nicotine addiction to reduce the global burden of CIDs.
Evaluating the effectiveness of integrated traditional Chinese and Western treatment based on symptom grading: a study protocol for a multi-center, randomized controlled trial of patients with depressive disorder
Authors: Mai Jiaxi , Zhou Tingwei , Wang Chen , Ye Junrong , Chen Jiao , Wang Wen , Pan Yuanxin , Wei Yanheng , Yuan Lexin , Yang Hang , Wu Shengwei , Guo Jianxiong , Xiao Aixiang 
Published: February 2025

BackgroundApproximately one-third of depressed individuals receive treatment globally. The application rate of traditional Chinese medicine (TCM) for treating depression globally remains relatively low. The proposed study presents a pilot trial to evaluate the effectiveness of interventions at different levels in improving depression status in community populations.MethodsA randomized controlled trial will be conducted in two communities in Guangdong, China, with a follow-up period of 12 weeks. Participants will be randomly allocated to control or intervention groups. Participants in the control group will be assigned to routine care, while participants in the intervention group will receive TCM intervention measures. The participants in the intervention group will receive integrated traditional Chinese and Western treatment according to the symptom grading of depression severity. Primary outcome measurements include the Patient Health Questionnaire (PHQ-9), the Hamilton Depression Rating Scale (HAMD-17), and the Self-Rating Depression Scale (SDS). Secondary outcome measurements include the Athens Insomnia Scale (AIS), the Epworth Sleepiness Scale (ESS), the Multiple Mental Health Literacy Scale (MMHL), the Short-Form 12 (SF-12), and the Treatment Emergent Symptom Scale (TESS). The data will be collected at baseline (T1), 2 weeks after intervention (T2), 4 weeks after intervention (T3), 8 weeks after intervention (T4), and 12 weeks after intervention (T5).DiscussionThis study will provide an experimental basis for the effectiveness of hierarchical integrated traditional Chinese and Western medicine (ITCWM) in improving the condition of patients with different degrees of depression. At the end of the study, it is expected for the experimental group to have an improvement in depressive symptoms and sleep quality and an enhancement in mental health awareness.Clinical trial registrationhttp://www.chictr.org.cn, identifier ChiCTR2300075169.
ENVOLVER+: a tool for the promotion of positive nursing practice environments
Authors: Ribeiro Olga Maria Pimenta Lopes , Schacht Ligia , Gonçalves Mariana Filipa Mendes , Faria Ana da Conceição Alves , Ribeiro Marlene Patrícia , Ventura-Silva João Miguel Almeida 
Published: February 2025

IntroductionPatients, nurses, and the organization itself can benefit from a good work environment. One of the weaknesses most often cited by nurses was the lack of involvement and participation in setting workplace policies. Using games is a promising strategy for promoting positive caregiving environments. The purpose of this study is to describe the process by which the ‘ENVOLVER+’ board game has been developed and validated.MethodsWe carried out a methodological study from September 2023 to May 2024 in three phases: (1) modified e-Delphi to validate the content to be included in the game; (2) development of the prototype board game; (3) application of the game in four practice contexts.ResultsThe four sessions of the ‘ENVOLVER+’ game lasted an average of 80 min. Each session had twelve participants in four groups. At the end of the sessions, we asked the participants to comment on the advantages and disadvantages of the game.DiscussionThe ‘ENVOLVER+’ game can be a valuable tool in promoting a positive nursing practice environment by providing an innovative and interactive approach to ensuring nurse involvement and participation.
Prevalence and associated factors of adult overweight and obesity in Southwestern China
Authors: Zhang Xiao-Qiang , Du Hua-An , Huang Chuan , Liu Jian-Xiong , Hu Yong-Mei , Liu Ya , Huang Xiao-Bo 
Published: February 2025

BackgroundData on the prevalence of overweight and obesity in Southwestern China were limited. The aims of this study were to estimate the prevalence of overweight/obesity and their associated factors in this area.MethodsA cross-sectional study was conducted from 2013 to 2014 in Chengdu and Chongqing, two megacities in Southwestern China. Data were obtained from questionnaires, physical examinations and lab tests. A total of 11,096 residents aged 35–79 years were included in the final analysis of this study.ResultsThe prevalence of overweight and obesity among adults aged 35–79 years in Southwestern China were 29.7 and 4.4%, respectively. Multivariable logistic regression analysis suggested that women, non-smokers, ex-smokers, being hypertensive and diabetic were related to higher obesity prevalence, and that physically active adults and those aged 65–79 years were less likely to have obesity.ConclusionObesity and overweight were prevalent in Southwestern China, especially among women, those with diabetes and/or hypertension, and those who have quitted smoking for more than 3 years.
Trend of skin cancer mortality and years of life lost in China from 2013 to 2021
Authors: Li Jingyi , Zeng Jiaqi , Yang Yuanchao , Huang Biran 
Published: February 2025

BackgroundThe mortality rates of skin cancer in Chinese population are increasing. However, research on skin cancer trends in China is limited. This study aimed to estimate the mortality trends of skin cancer in China within 2013–2021.MethodsA retrospective analysis of skin cancer deaths within 2013–2021 was performed using the China death cause surveillance dataset compiled by the National Health Commission Statistics Information Center and the China Center for Disease Control and Prevention Chronic Non-Communicable Diseases Prevention and Control Center. The mortality rates of skin cancer were stratified by gender, age group, and area (urban or rural).ResultsFrom 2013 to 2021 in China, the crude mortality rate (CMR) of skin cancer increased, and the age-standardized mortality rate (ASMR), and age-standardized years of life lost (YLL) rate decreased. The ASMR and age-standardized YLL rate were 0.85/100,000 and 18.95/100,000 in 2013, respectively, and decreased to 0.75/100,000 and 16.84/100,000, respectively, in 2021. From 2013 to 2021, the CMR, ASMR, and age-standardized YLL rate of skin cancer were higher in males than in females and higher in rural areas rather than in urban ones. In terms of the highest age-specific mortality rate, it appeared in the age group of over 85 years old.ConclusionThe burden of skin cancer remained heavily from 2013 to 2021 in China. Especially males, older adult, and rural residents had higher mortality. Thus, effective measures and strategies should be taken to reduce the incidence and mortality of skin cancer.
Global burden of ischemic heart disease in older adult populations linked to non-optimal temperatures: past (1990–2021) and future (2022–2050) analysis
Authors: Liu Lihui , He Yisong , Huang Gang , Zeng Yangxi , Lu Jiaan , He Ru , Chen Haiqing , Gu Yuheng , Hu Qingwen , Liao Bin , Wan Juyi 
Published: February 2025

BackgroundIschemic heart disease (IHD) is a leading cause of death and disability, particularly affecting the older adult population. Extreme temperatures, especially very low and very high temperatures, are known to exacerbate cardiovascular disease burden. With the ongoing global climate change, understanding the impact of non-optimal temperatures on IHD burden becomes increasingly important, especially in vulnerable populations such as the older adult.MethodsThis study used data from the Global Burden of Disease Study 2021 (GBD 2021) to analyze the spatiotemporal trends of low and high temperatures on IHD burden in the older adult population (aged 60 and above) from 1990 to 2021. We used age-standardized rates (ASR), annual percentage change (EAPC), and the Bayesian age-period-cohort (BAPC) model to forecast 2050. Additionally, the geographic differences in IHD burden were analyzed using World Bank regions.ResultsFrom 1990 to 2021, the IHD burden in the older adult population was mainly attributed to low temperatures. However, it has increased the burden of IHD due to high temperatures, especially in tropical and low-income regions. The analysis of gender difference revealed that men are usually more affected by high temperatures, though generally, women are more sensitive to low temperatures. Forecasts are that in the future, the burden of IHD due to high temperatures will continue to rise, especially in areas with limited adaptive capacity.ConclusionAlthough low temperature remains the most important contributor to IHD burden among the older adult, the burden attributable to high temperature is on the rise, which increases the need to address the extreme temperature fluctuation. That is more so in poor-income and tropical regions where the most vulnerable populations bear a higher risk for health. Thus, there is an urgent need to develop adaptive public health measures against the dual health risks from extreme temperatures. The findings emphasize that targeted interventions are necessary, with adjustments in regional differences and gender-specific risks to effectively address the growing health threats from climate change.
Pervasive systemic disparities: medical-related gaslighting, trauma, and distrust among LGBTQ+ people in the United States
Authors: Nowaskie Dustin Z. , Blackwood Dehandra , Garcia Frank 
Published: February 2025

IntroductionHistorically, LGBTQ+ people have and continue to endure discrimination across many contexts, including healthcare. Research and data from nationwide samples in the United States regarding medical-related stigma experienced by LGBTQ+ people are scant.MethodsA cross-sectional survey was distributed online to a national sample of United States residents. Participants answered questions about their healthcare, including experiences with medical-related gaslighting, trauma, and trust.ResultsCompared to cisgender and heterosexual people (n = 857), LGBTQ+ people (n = 815) reported significantly higher rates of medical-related gaslighting (46.5% vs. 26.5%, ORs 1.75–2.80) and trauma (18% vs. 8.9%, ORs 1.63–2.66). Likewise, LGBTQ+ people conveyed significantly less trust (ORs 0.46–0.53) in primary care providers (59.8% vs. 74.1%), medical specialists (56.5% vs. 71.7%), pharmaceutical companies (17% vs. 28%), insurance companies (15.9% vs. 29.3%), and U.S. healthcare systems (17.8% vs. 30.4%).DiscussionMedical-related gaslighting, trauma, and distrust are pervasive systemic disparities among LGBTQ+ people. Addressing these challenges will require ongoing, lifelong motivation, dedication, and commitment for LGBTQ+ education, advocacy, and leadership to dismantle current prejudiced practices and foster more inclusive, supportive, affirming healthcare environments.
A randomized comparative effectiveness trial to evaluate two programs for promotion of physical activity after spinal cord injury in manual wheelchair users
Authors: Martinez Jenna M. , Haubert Lisa L. , Eberly Valerie J. , Weiss Walter B. , Rankin Jeffery W. 
Published: February 2025

ObjectiveThe goal of this study was to determine the effectiveness of a novel whole of day activity accumulation (WODAA) physical exercise program. WODAA physical activity and physiological outcomes were compared to outcomes from individuals using a traditional planned arm crank exercise (PACE) program. Both programs included progressive exercise instruction and goal setting over a 4-month period, and utilization of a wrist-worn activity monitor (Fitbit Blaze/Versa, Fitbit Inc., San Francisco, CA).DesignLongitudinal, randomized, comparative effectiveness trial with collaborative goal setting.SettingResearch laboratory at a rehabilitation hospital and in participants' homes and communities.ParticipantsForty-nine manual wheelchair users with paraplegia.Outcome measuresPhysical activity measurements and cardiometabolic data were collected before, during, and after the program. The primary measures were amount of daily arm activity (Steps) and time spent in different activity and heart rate zones.ResultsRelative to baseline measures, participants in the WODAA group had significantly more daily arm movement/propulsion activity (Steps) and time spent in the Fairly and Very Active Zones and the Cardio Heart Rate Zone compared to those in the PACE group over the final month of the intervention (p &lt; 0.05). Minutes spent in other Activity and Heart Rate Zones were similar between groups. At final evaluation, diastolic blood pressure after a 6-Minute Push Test was significantly lower in the WODAA group, while no differences were found in distance traveled, systolic, or pre-test diastolic blood pressures. Metabolic bloodwork and shoulder pain scores did not change and were similar between groups.ConclusionDepending on the measure used, these findings suggest that a WODAA approach to PA is comparable or more effective than a traditional PACE program in promoting physical activity in low-active manual wheelchair users with paraplegia.
Enhancing Functional Properties and Shelf Life of Oryza sativa L. via Grain Stabilization Techniques
Authors: Song Eunsu , Gwon Hyeeun , Choi Jaeyoung , Islam Md Atiqual , Chun Jiyeon , Chang Yun Hee , Hwang Jinah 
Published: February 2025

Background: Oryza sativa L. is one of the main staple crops in the South Korea. While rice production has remained stable over the past decades, rice consumption has gradually declined, leading to a rapid stockpile in rice inventory. Conventional rice storage methods often fail to preserve functional properties and long-term stability, necessitating innovative processing techniques. Methods: To address this issue, we developed a grain stabilization technique (GST) to enhance the functionality and shelf life of white rice (WR), brown rice (BR), and rice germ (RG). The GST process was conducted in a single-batch system, integrating a controlled temperature cycle (65~85 °C) with 60 rpm rotation, far-infrared (26,400 W/m2), and ultraviolet (254 nm, 60,880 J/m2) irradiation in an enclosed chamber equipped with an exhaust system for moisture, odor, and impurity removal. The process was followed by air drying (25 °C, 15 h) to ensure stability. Results: The GST significantly increased resistant starch content in BR and WR by 214% and 27%, respectively, but not in RG. Additionally, GST enhanced the contents of campesterol, stigmasterol, β-sitosterol, and octacosanol in BR and RG, but not significantly in WR. Furthermore, this technique markedly reduced moisture content, acidity, and bacterial counts over a 90-day storage period and kept mycotoxin levels within safe limits in WR, BR, and RG. GST also altered the microstructures of WR and BR, indicating gelatinization and amorphization of starch granules. Conclusions: These findings contribute to advancing food science by presenting GST as a transformative method to extend shelf life and improve the nutritional profile of rice, aligning with global efforts to reduce food waste, improve dietary health, and develop sustainable food processing technologies.
Hepatitis Associated with Catha edulis Consumption—A Single-Center Study
Authors: Someili Ali , Mohrag Mostafa , Abdulrasak Mohammed 
Published: February 2025

Background/Objectives: Catha edulis, also known as Khat, is a stimulant with hepatotoxic properties. Studies reporting laboratory patterns are scarce. The aim was to assess the patterns associated with hepatic dysfunction due to Khat usage. Methods: Patients with liver injury and self-reported Khat consumption presenting to the gastroenterology department at the King Fahad Central Hospital in Jazan between January 2017–May 2024 were retrospectively included in the study. Patients with any signs of cirrhosis or viral hepatitis were excluded to have a more homogenous inclusion. Normal distribution was not assumed; data were presented as the median (IQR or %). Results: Sixty-three patients (of which 62 (98.4%) were male) aged 35 (29–41) years were included in the study. An IgG > 20 g/L was present in 41 (61.5%) patients, and the majority (n = 48, 76.2%) had a hepatocellular injury pattern based on an R-factor > 5. Over half of the patients had at least one positive autoantibody(ANA 47.6%; SMA 55.6% and AMA 4.8%), while 57 (90.5%) patients received immunosuppressive therapy. Conclusions: Khat-induced liver injury seems to be predominantly AIH-like in nature, given the IgG elevation, hepatocellular injury pattern, and relatively high rate of autoantibody positivity.
Гармонизация регулирования региональной трудовой миграции
Authors: Якшибаева Г.В. , Имамов М.М. 
Published: February 2025

В статье рассматривается современное состояние трудовой миграции в России. Проведенное исследование и анализ миграционной ситуации в регионах страны свидетельствуют о доминировании преимущественно стихийного, а не регулируемого движения рабочей силы. Выявлены проблемы в сфере движения трудовых мигрантов. Предложен авторский подход, основанный на применении рыночных и плановых (государственных) методов, направленный на гармонизацию регулирования трудовой миграции в регионах РФ и обеспечение количественно-качественного соответствия факторов производства.
The article examines the current state of labor migration in Russia. The conducted research and analysis of the migration situation in the regions of the country showed the dominance of spontaneous labor movement rather than regulated. The problems in the sphere of the movement of labor migrants have been identified. The author's approach based on the application of market and planned (state) methods is proposed, aimed at harmonizing the regulation of labor migration in the regions of the Russian Federation and ensuring the quantitative and qualitative conformity of production factors.