bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Antituberculosis Activity of Some N‐Pyridyl‐N′‐thiazolylhydrazine Derivatives.
Authors: Turan‐Zitouni Guelhan , Kaplancikli Zafer Asim , Oezdemir Ahmet 
Published: July 2010

AbstractNew N‐pyridyl‐N′‐thiazolylhydrazine derivatives (III) are prepared and evaluated for their activity against Mycobacterium tuberculosis H37Rv.
ChemInform Abstract: Hafnium (IV) Bis(perfluorooctanesulfonyl)imide Complex Catalyzed Synthesis of Polyhydroquinoline Derivatives via Unsymmetrical Hantzsch Reaction in Fluorous Medium.
Authors: Hong Mei , Cai Chun , Yi Wen‐Bin 
Published: July 2010

AbstractThe four‐component condensation of dimedone (I), aldehydes (II), active methylene compounds (III), and ammonium acetate is conducted in the presence of the title catalyst in perfluorodecalin to produce the polyhydroquinoline derivatives (IV) in good to very good yields.
ChemInform Abstract: Catalytic Enantioselective 1,3‐Dipolar Cycloaddition of C,N‐Cyclic Azomethine Imines with α,β‐Unsaturated Aldehydes.
Authors: Hashimoto Takuya , Maeda Yuko , Omote Masato , Nakatsu Hiroki , Maruoka Keiiji 
Published: July 2010

AbstractA titanium/(S)‐BINOL complex catalyzes the title reaction of azomethine imines (I) to give a variety of pharmaceutically attractive chiral pyrazolo‐fused tetrahydroisoquinolines.
ChemInform Abstract: Highly Diastereoselective Synthesis of Substituted Pyrrolidines Using a Sequence of Azomethine Ylide Cycloaddition and Nucleophilic Cyclization.
Authors: Belanger Guillaume , Darsigny Veronique , Dore Michael , Levesque Francois 
Published: July 2010

AbstractThis new method allows formation of a number of indolizidine derivatives with high diastereoselectivity.
ChemInform Abstract: Synthesis of Aza‐Fused Polycyclic Quinolines Through Copper‐Catalyzed Cascade Reactions.
Authors: Cai Qian , Li Zhengqiu , Wei Jiajia , Fu Liangbin , Ha Chengyong , Pei Duanqing , Ding Ke 
Published: July 2010

AbstractA broad spectrum of target compounds is prepared with good yields starting from benzimidazole (I) via an intermolecular condensation followed by intramolecular C—N coupling.
ChemInform Abstract: Pd(II)‐Catalyzed Synthesis of Carbolines by Iminoannulation of Internal Alkynes via Direct C—H Bond Cleavage Using Dioxygen as Oxidant.
Authors: Ding Shengtao , Shi Zhuangzhi , Jiao Ning 
Published: July 2010

AbstractConditions A) in the absence of any ligands make the Pd‐catalyzed direct dehydrogenative annulation very easy to handle.
ChemInform Abstract: Enantioselective [4 + 2] Cycloaddition of Ketenes and 9,10‐Phenanthrenequinone Catalyzed by N‐Heterocyclic Carbenes.
Authors: Shao Pan‐Lin , Chen Xiang‐Yu , Sun Li‐Hui , Ye Song 
Published: July 2010

AbstractChiral N‐heterocyclic carbenes, generated from tetrafluoroborates (I) and cesium carbonate, are investigated as catalysts for the asymmetric [4 + 2] cycloaddition of alkyl aryl ketones with o‐quinones.
ChemInform Abstract: Highly Effective Stereoselective Synthesis of Vinyl Ethers of 5‐Alkyl‐2‐(2‐furyl)‐5‐hydroxymethyl‐1,3‐dioxanes.
Authors: Trofimov B. A. , Oparina L. A. , Vysotskaya O. V. , Stepanov A. V. , Gusarova N. K. 
Published: July 2010

AbstractAn effective and stereoselective method for the synthesis of new dioxanes (V) containing furan heterocycles and vinyloxy groups is developed.
ChemInform Abstract: Synthesis and Anticonvulsant Activity of a New 6‐Alkoxy‐[1,2,4]triazolo[4,3‐b]pyridazine.
Authors: Guan Li‐Ping , Sui Xin , Deng Xian‐Qing , Quan Ying‐Chun , Quan Zhe‐Shan 
Published: July 2010

AbstractTitle compounds (III) are synthesized by condensation with formylhydrazine.
ChemInform Abstract: Synthesis of 9‐Alkyl‐6‐amino[1,2,4]triazolo[3,4‐c]‐5‐azaquinoxalines. Mild and Effective SNAr Amination of Highly Electron‐Poor Heterocycles.
Authors: Unciti‐Broceta Asier , Pineda‐de‐las‐Infantas Maria Jose , Gallo Miguel Angel , Espinosa Antonio 
Published: July 2010

AbstractThe previously reported substrates (I) readily undergo an SNAr reaction with ammonia in acetonitrile solution under thermal or microwave conditions.
ChemInform Abstract: Fused Polycyclic Nitrogen‐Containing Heterocycles. Part 21. Condensation of 4‐Hydroxy‐3,5‐diphenyl‐2‐phenyliminothiazolidine with 5‐Fluoro‐4‐morpholino‐ and ‐4‐(4‐methylpiperazino)‐1,2‐phenylenediamines.
Authors: Mamedov V. A. , Zhukova N. A. , Beschastnova T. N. , Balandina A. A. , Gubaidullin A. T. , Kotovskaya S. K. , Latypov Sh. K. , Levin Ya. A. , Charushin V. N. 
Published: July 2010

AbstractThe title reaction results in the formation of regioisomeric thiazoloquinoxalines (III)/(IV).
ChemInform Abstract: Synthesis and Anticonvulsant Activity of New Kojic Acid Derivatives.
Authors: Aytemir Mutlu Dilsiz , Septioglu Ebubekir , Calis Uensal 
Published: July 2010

AbstractA series of novel Mannich bases of kojic acid (IV) (15 examples) are synthesized and evaluated for their anticonvulsant activity and neurotoxicity.
ChemInform Abstract: Synthesis of Novel Fused Azecine Ring Systems Through Application of the tert‐Amino Effect.
Authors: Dunkel Petra , Turos Gyoergy , Benyei Attila , Ludanyi Krisztina , Matyus Peter 
Published: July 2010

AbstractMicrowave heating of the vinylic amines (VII) and their pyridazinone analogues such as (XII) allows a new and straightforward access to fused azecine ring systems like (VIII) and (XIII).
ChemInform Abstract: Ga(III)‐Catalyzed Cycloisomerization Approach to (.+‐.)‐Icetexone and (.+‐.)‐epi‐Icetexone.
Authors: de Jesus Cortez Felipe , Sarpong Richmond 
Published: July 2010

AbstractAn expedient route to the tetracyclic lactones (IV) and (V), precursors of icetexone and epi‐icetexone, is reported.
ChemInform Abstract: Triterpenoids from Angiopteris palmiformis.
Authors: Chen Chiy‐Rong , Liao Yun‐Wen , Wu Hui‐Ting , Shih Wen‐Ling , Tzeng Chih‐Ying , Yang Sheng‐Zehn , Hernandez Carlos Eduardo , Chang Chi‐I 
Published: July 2010

AbstractCompounds (I), (III) and (IV) exhibit promising cytotoxic activity against human hepatoma SK Hep‐1 cells.
ChemInform Abstract: Addition of Alkyl Radicals, Generated from Carboxylic Acids via Photochemical Decarboxylation, to Glyoxylic Oxime Ether: A Mild and Efficient Route to α‐Substituted α‐Aminoesters.
Authors: Yoshimi Yasuharu , Kobayashi Kosuke , Kamakura Hayato , Nishikawa Keisuke , Haga Yoshiki , Maeda Kousuke , Morita Toshio , Itou Tatsuya , Okada Yutaka , Hatanaka Minoru 
Published: July 2010

AbstractIt is found that carboxylic acid serves both as a Broensted acid and as a radical source.
ChemInform Abstract: Reactions of Stereocontrolled Intramolecular Carbocyclization of Levoglucosenone Adduct with Isoprene.
Authors: Sharipov B. T. , Krasnoslobodtseva O. Yu. , Spirikhin L. V. , Valeev F. A. 
Published: July 2010

AbstractThe transformation of the levoglucosinone adduct (I) and related derivatives into carbocycles is studied in detail.
ChemInform Abstract: Swerilactones E‐G, Three Unusual Lactones from Swertia mileensis.
Authors: Geng Chang‐An , Zhang Xue‐Mei , Ma Yun‐Bao , Jiang Zhi‐Yong , Luo Jie , Zhou Jun , Wang Hong‐Ling , Chen Ji‐Jun 
Published: July 2010

AbstractSignificant anti‐HBV activity in vitro is observed for swerilactone E (I) and F (II).
ChemInform Abstract: Preventive Action of Nobiletin, a Constituent of AURANTII NOBILIS PERICARPIUM with anti‐Dementia Activity, Against Amyloid‐β Peptide‐Induced Neurotoxicity Expression and Memory Impairment
Authors: Yamakuni Tohru , Nakajima Akira , Ohizumi Yasushi 
Published: July 2010

AbstractReview: 11 refs.
Assessment of potential immunotoxic effects caused by cypermethrin, fluoxetine, and thiabendazole using heat shock protein 70 and interleukin-1β mRNA expression in the anuran Xenopus laevis
Authors: Martini Federica , Fernández Carlos , Segundo Laura San , Tarazona José V. , Pablos M. Victoria 
Published: July 2010

Abstract
The current study describes the effect of cypermethrin, fluoxetine, and thiabendazole, at environmentally relevant concentrations, on the expression of heat shock protein 70 (HSP70) and interleukin 1β (IL-1β), using Xenopus laevis larvae as animal model. Cytokines and interleukins are considered good predictors of the immunotoxic potential of xenobiotics. Tadpoles at stage 47 (normal tables of X. laevis) were exposed under static conditions to: 0.3 and 30 µg/L fluoxetine, 0.7 µg/L thiabendazole, and 0.24 µg/L cypermethrin. The effects were evaluated at 7, 24, and 72 h, and 6 and 9 d. Randomly chosen tadpoles were used as genetic material for detection of hsp70 and IL-1β mRNA induction through reverse transcription PCR. Tadpoles exposed to 30 µg/L fluoxetine showed mRNA expression of both genes at all exposure times, whereas at 0.3 µg/L a peak response for hsp70 was observed after 24 h, and the increase in IL-1β mRNA was statistically significant with respect to the control 72 h after exposure. Thiabendazole induced a high expression of mRNA for both hsp70 and IL-1β at all exposure times. Cypermethrin increased the hsp70 mRNA levels, with a peak at 24 h, and provoked high expression of IL-1β mRNA at all exposure times. Considering the relationship between HSP70 and IL-1β and their involvement (mainly of IL-1β) in immune responses, certain changes observed in their expression could be considered warning indicators of potential immunotoxic effects of these substances on Xenopus. Environ. Toxicol. Chem. 2010;29:2536–2543. © 2010 SETAC
Zellen mit zurückgedrehter Uhr
Authors: Groß Michael 
Published: July 2010

AbstractNur vier Faktoren sind nötig, um aus ausdifferenzierten Zellen der Maus pluripotente Stammzellen zu gewinnen, die sich nicht mehr von embryonalen Stammzellen unterscheiden. Einer Übertragung des Prinzips auf den Menschen steht allerdings das hohe Krebsrisiko im Weg.
Von der Revolution zur Reife
Authors: Karas Michael , Hillenkamp Franz 
Published: July 2010

AbstractDas Wachstum der Proteomics hat in den letzten Jahren die Entwicklung massenspektrometrischer Instrumente und Methoden angetrieben. Der Weg vom Massenspektrum zu biologischer Information ist aber nach wie vor weit und Grundlagenforschung bleibt unverzichtbar – ein Überblick über aktuelle Trends in der Massenspektrometrie.
Die zwei Gesichter des Lithiums
Authors: Sollmann Dominik 
Published: July 2010

AbstractIn Batterien liefert Lithium die konkurrenzlos besten Energiedichten. Doch zehn Millionen Notebook‐Akkumulatoren, welche die Hersteller wegen Brandgefahr in den vergangenen Monaten zurückriefen, zeigen die andere Seite des Lithiums: seine hohe Reaktivität.
Kunststoffindustrie: transparent und glänzend
Authors: Bulmahn Maren 
Published: July 2010

AbstractDie Automobilindustrie reduziert mit Kunststoffen Gewicht. Polymere sind angenehm zu berühren und schön anzuschauen – Eigenschaften, die Verpackungen gut anstehen. Polyethylen und Polyvinylchlorid machen Miniaturisierung in der Medizintechnik möglich.
Knowledge lost in information
Authors: Hopf Henning 
Published: July 2010

AbstractImmer mehr Veröffentlichungen, immer mehr wissenschaftliche Zeitschriften – ein Informations‐Tsunami scheint uns zu überrollen. Doch gleichzeitig herrscht Unsicherheit darüber, ob die traditionelle Form des wissenschaftlichen Publizierens nicht doch ein Auslaufmodell ist. Liegt die Zukunft gar im open access?
Kommunikation und Konsortien
Authors: Jung Robert 
Published: July 2010

AbstractReach fordert von der chemischen Industrie bereichs‐ und unternehmensübergreifende Abstimmung und Zusammenarbeit. Doch Reach birgt auch Chancen: Öffentlichkeit und Investoren honorieren nachhaltige und umweltverträgliche Maßnahmen.
An Integrative Approach to Genomic Introgression Mapping
Authors: Severin Andrew J. , Peiffer Gregory A. , Xu Wayne W. , Hyten David L. , Bucciarelli Bruna , O’Rourke Jamie A. , Bolon Yung-Tsi , Grant David , Farmer Andrew D. , May Gregory D. , Vance Carroll P. , Shoemaker Randy C. , Stupar Robert M. 
Published: July 2010

Abstract
Near-isogenic lines (NILs) are valuable genetic resources for many crop species, including soybean (Glycine max). The development of new molecular platforms promises to accelerate the mapping of genetic introgressions in these materials. Here, we compare some existing and emerging methodologies for genetic introgression mapping: single-feature polymorphism analysis, Illumina GoldenGate single nucleotide polymorphism (SNP) genotyping, and de novo SNP discovery via RNA-Seq analysis of next-generation sequence data. We used these methods to map the introgressed regions in an iron-inefficient soybean NIL and found that the three mapping approaches are complementary when utilized in combination. The comparative RNA-Seq approach offers several additional advantages, including the greatest mapping resolution, marker depth, and de novo marker utility for downstream fine-mapping analysis. We applied the comparative RNA-Seq method to map genetic introgressions in an additional pair of NILs exhibiting differential seed protein content. Furthermore, we attempted to optimize the comparative RNA-Seq approach by assessing the impact of sequence depth, SNP identification methodology, and post hoc analyses on SNP discovery rates. We conclude that the comparative RNA-Seq approach can be optimized with sufficient sampling and by utilizing a post hoc correction accounting for gene density variation that controls for false discoveries.
Sex role orientation and conflict resolution in the joint purchase decisions of spouses
Authors: Makgosa Rina 
Published: July 2010

PurposeThe purpose of this paper is to investigate how the effects of sex role orientation (SRO) on conflict resolution strategies vary across ethnic groups.Design/methodology/approachA questionnaire was used with a sample of 295 husbands and 288 wives of British White, Indian and African Black origin residents of London and Manchester in the UK.FindingsThe results showed that SRO had a significant impact on conflict resolution strategies for both husbands and wives across the three British ethnic groups. A modern SRO encourages bargaining within all the three ethnic groups and playing on emotion, disengagement and assertiveness for Indians and African Black husbands. In addition, a modern SRO increases bargaining for African Blacks wives and playing on emotion, supplication and assertiveness for British Whites wives.Research limitations/implicationsOverall, the paper provides substantial evidence of differences in the use of conflict resolution strategies by husbands and wives from the three ethnic groups.Originality/valueThe paper contributes to knowledge about differences in the effects of SRO on conflict resolution strategies used in joint purchase decisions for major household durables in a multicultural country.
Tourism and hospitality small and medium enterprises and environmental sustainability
Authors: Alonso Abel D. , Ogle Alfred 
Published: July 2010

PurposeWhile environmental sustainability is increasingly gaining relevance, it appears to have been ignored in certain areas, such as in research on water usage of small and medium enterprises (SMEs) in the hospitality and tourism industries. The purpose of this paper is to examine this dimension from the perspective of the operators.Design/methodology/approachSemi‐structured face‐to‐face and telephone interviews were conducted with ten managers/operators in the Swan Valley region of Western Australia.FindingsStrong manager/operator awareness of the impact of their actions on the environment was demonstrated. Also salient was the factors impinging on implementation of environmental initiatives. Business demands or added costs also present challenges in fully materializing an operator's environmentally sustainable practices, particularly concerning water consumption in service areas, such as in toilets, which represents a large proportion of total water usage.Research limitations/implicationsThe limited number of participants does not allow for making generalizations of environmentally sustainable practices among SMEs in the hospitality and tourism sector. However, this exploratory study provides insights into an area that has received very limited attention in academic research.Practical implicationsAs environmental issues may increasingly become more serious, the engagement of managers, operators, the wider business community and other bodies at different levels is critical. In this regard, the study provides several implications for these stakeholders.Originality/valueVery few studies have attempted to investigate environmental issues among small hospitality and tourism enterprises. This paper not only seeks to close knowledge gaps in an under‐researched area but also to open the door for future studies in the area.
Working time management and SME performance in Europe
Authors: Smith Mark , Zagelmeyer Stefan 
Published: July 2010

PurposeThis paper aims to explore the management of working time flexibility and firm performance, measured by operating hours, in small and medium‐sized enterprises (SMEs) in Europe.Design/methodology/approachThe paper analyses the European Capital Operating time, Work and Employment Survey (EUCOWE), designed to collect workplace information on operating hours. With data on more than 17,000 establishments in six European countries – France, Germany, The Netherlands, Portugal, Spain and the UK – the paper analyses working time patterns and operating hours.FindingsThe authors show the positive relationship between company size and operating times and how SMEs make more limited use of more advanced forms of working‐time organisation that may allow them to extend their operating hours. The use of less complex working time measures such as overtime does not have the same positive association with operating hours. However, the results also highlight that smaller establishments can still benefit from the adoption of certain working time practices. The results suggest that the influence of the regulatory environment on the use of working practices or the duration of operating hours is not straightforward, and as such the impact of national regulatory frameworks cannot be discounted in the country‐specific differences identified.Originality/valueThe paper uses the first comparable data on operating hours and working patterns to demonstrate the limitations on SME operating times across European countries.
The risks of being a lone mother on income support in Canada and the USA
Authors: Gazso Amber , McDaniel Susan A. 
Published: July 2010

PurposeThis paper aims to explore how neo‐liberalism shapes income support policy and lone mothers' experiences in Canada and the USA.Design/methodology/approachA critical comparative analysis is undertaken of how Canadian and US governments take up sociological concepts of risk, market citizenship, and individualization, whether explicitly or implicitly, in the design and administration of neo‐liberal income support policies directed at lone mothers. Specifically, the contradictory life circumstances that Canadian and American lone mothers experience when they access income supports that are designed ostensibly to construct/reconstruct them as citizens capable of risk taking in their search for employment and self‐sufficiency are compared.FindingsThe paper finds that the realities for poor lone mothers are remarkably similar in the two countries and therefore argue that income support policies, particularly welfare‐to‐work initiatives, underpinned by neo‐liberal tenets, can act in a counter‐intuitive manner exposing lone mothers to greater rather than lesser economic and social insecurity/inequality, and constructing them as risk aversive and dependent.Research limitations/implicationsThe economic and social implications/contradictions of neo‐liberal restructuring of income support policies for lone mothers is revealed.Originality/valueThis paper contributes to broader scholarship on the gendered dimensions of neo‐liberal restructuring of welfare states in late modernity.
Supply strategy and business performance
Authors: González‐Benito Javier 
Published: July 2010

PurposeThe purpose of this paper is to analyze the effect of purchasing and supply strategies on business performance.Design/methodology/approachThe empirical results are based on information provided on a questionnaire by purchasing managers in 180 Spanish industrial firms.FindingsAn organization's commercial and financial performance increases when it increases the relative importance of flexibility and decreases the relative importance of reductions in stock levels and purchasing prices in its supply strategy. The best performing firms are those that combine quality, dependability, and flexibility as priority objectives and relegate cost reductions to secondary importance.Research limitations/implicationsAlthough the research is designed to mitigate the effect of common method bias, it still depends on perceptual measures of performance. Further research should enlarge the list of generic competitive objectives to take into account newer dimensions cited in existing literature, such as innovation or environmental management.Practical implicationsThe results provide useful information for managers who wish to configure an optimal profile of competitive objectives for their purchasing and supply function.Originality/valueThe paper uses an approach that introduces two innovative elements. First, strategy is conceived of as a profile of generic competitive objectives, not as a set of practices deployed by the purchasing function. Second, the study introduces the concept of the relative importance of a competitive objective, rather than the absolute importance of that objective, which enables an analysis of the effect of the interrelationships among the different competitive objectives.
Antecedents and outcomes of manufacturability in integrated product development
Authors: Doll William J. , Hong Paul , Nahm Abraham 
Published: July 2010

PurposeThe purpose of this paper is to present a model linking the role of design engineers to shared team knowledge, enhanced manufacturability, and product development outcomes. New product manufacturability is a quality of the product design that indicates the ease and reliability by which an organization develops products by using its manufacturing and supply chain resources.Design/methodology/approachThe model is tested using a sample of 205 product development projects from firms in the USA and Canada.FindingsThe findings of the large‐scale empirical study suggest that by facilitating informing practices among functional specialists, design engineers help translate a functional portrayal of the product in terms of customer attributes, to a form description in terms of engineering characteristics, and then to a fabrication view in terms of manufacturing processes.Practical implicationsNew product manufacturability can be a distinctive competency that provides competitive advantage by lowering costs, improving customer value, and speeding products to market.Originality/valueIn contrast to previous research that showed that role changes of design engineers have a narrow impact on development productivity (e.g. improving resource allocation), this paper suggests that these role changes of design engineers have a much broader impact on manufacturability and, through this, improve manufacturing cost, time‐to‐market, and value‐to‐customers.