bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dependence in Sociology: An Empirical Study of Asian Countries
Authors: Kumar Krishna , Raju Sripada 
Published: January 2010

AbstractSince the late sixties and seventies, there has been a well articulated concern in Asian countries about the "all pervasive" intellectual influence of Europe and the United States on social sciences in general and sociology in particular (Ashraf 1975; Alatas 1972, 1974; Kothari 1968; Kumar 1978; Goonatilake 1975; Singh 1973). A section of the social science community has suggested that while the diffusion of sociological knowledge-frameworks, paradigms, concepts, theories, methodologies, and substantive findings-from Europe and the United States has undoubtedly laid the foundations of sociology in Asia, it has also contributed to her intellectual dependence in the discipline. As a result of this diffusion process, the parameters of sociological reflection and research in Asia are being largely set by sociologists based in the North American and West European nations. Such a state of affairs, according to this view, stifles the creativity of Asian sociologists and comes in the way of the growth of sociological knowledge relevant to their needs and aspirations. The main purpose of the present paper is to examine with empirical data two questions related to the above concern: first, whether there is any intellectual dependence of sociology in Asia on Western nations, particularly the United States; second, whether this intellectual dependence, if it does exist, is increasing or decreasing over time. Bibliometric reference data from professional journals of six nations have been used to investigate these two questions.
Ethnicity and the Language Used as a Medium of Instruction in Schools
Authors: Kalab Milada 
Published: January 2010

AbstractThis paper is based mainly on personal experiences in two very different areas. Between 1954 and 1956 I was employed as a teacher in Manipur State in India. I taught for one academic year at the Somdal Ningkhalen High School near Ukhrul in the Tangkhul Naga area and for three months at the Zeliangroung High School at Tamenglong. I was expelled from there in March 1956. Ten years later I spent ten months in field-work in Cambodia, mainly at Prek Por in Kompong Cham Province. And in 1972 I spent six months in two villages in Surin Province in Thailand. As I was not studying language policy or ethnicity this account will necessarily be sketchy and tentative. What interests me is the difference between the policies in India and in Southeast Asia; while all these states are trying hard to encourage the use of a national language, their emphasis and their policies towards ethnic minorities vary.
Notes on Ethnic Factors Related to Development in Sulawesi, Indonesia
Authors: Babcock Tim G. 
Published: January 2010

AbstractThe island (more accurately, islands) of Sulawesi is a large and important part of Indonesia1 which certainly deserves more studies of its peoples and resources than is currently the case. These short notes provide some recent information on ethnicity and development in Sulawesi, and are presented mainly as problems that should concern future researchers and planners working in the area. Since the beginning of 1974 I have spent four and half years in Sulawesi, first studying the descendants of Javanese and other exiles in North Sulawesi. Later, I served as consultant anthropologist to the Sulawesi Regional Development Study, a project supported by the Canadian International Development Agency and the Indonesian Department of Public Works.2 During the latter project I visited almost all the kabupaten or administrative subdivisions of the four provinces of Sulawesi. Although the nature of the project did not allow for in-depth research, many problems related to ethnicity and development soon became apparent. Many of the government and secondary reports on the region collected during the study revealed a lack of concern for such issues. It is therefore all the more important that a brief outline of ethnic groups in Sulawesi be presented. The second major reason for these notes is the fact that Sulawesi, along with the other "Outer Islands", is receiving increasing amounts of national and international aid to carry out a wide variety of development projects for its people. It is therefore important that scholars and government officials should be aware of the effects of these projects and to establish how to go about studying them so as not to destroy the socio-cultural life of the Sulawesi people.
Inter-ethnic Restructuring in Malaysia, 1970-80: The Employment Perspective
Authors:   Tai Yoke Lin
Published: January 2010

AbstractThe New Economic Policy (NEP) was launched in 1970 in the aftermath of the racial riots of May 1969 which were widely held as an expression of the discontent felt among Malays vis-à-vis Chinese domination of the Malaysian economy. Under this new strategy, more rapid "Malaysianization" of society was planned and a commitment was made to "restructure" the economy so as to give Malays an economic status equivalent, or equal, to that of non-Malays. Efforts extended from increasing Malay equity participation in industry and upgrading the employment structure of Malays to poverty eradication, notably in low-income rural areas where most Malays live. The target date for completion of the process of restructuring was 1990 but before that a series of detailed plans mapped out evolving strategies to achieve a steady progression in the restructuring process. It is in this context that this paper sets out to examine the main trends in the employment structure over the past quarter of a century, within limits of data availability, to see to what extent ethnic restructuring has occurred and the nature of the changes that have taken place.
Changes in the South Indian Hindu Family Structure in West Malaysia
Authors: Susan Oorjitham K.S. 
Published: January 2010

AbstractThe largest group of Indians in West Malaysia are the Tamil-speaking Hindus who originate from South India, particularly from Tamilnad. According to S. Arasaratnam, not only are 80% of Indians in Malaysia Tamil speakers but a vast majority of them are also Hindus.1 It is further established that the majority of this group are members of the working class, either in the plantation or in the urban sectors. The family structures of these Tamil working-class families originate basically from the traditional Indian family structure of India. This traditional Indian family structure was maintained in the "conducive" environment of ethnic isolation, found in the plantations. Since my purpose is to study changes in the family structure, Tamil working-class families in an urban environment were selected. It is expected that some changes in family values and structures have occurred among this group of Indians in West Malaysia.
Association of Maximum Pitch Velocity and Elbow Injury in Professional Baseball Pitchers
Authors: Bushnell Brandon D. , Anz Adam W. , Noonan Thomas J. , Torry Michael R. , Hawkins Richard J. 
Published: January 2010

Background Recent literature has explored the association of upper extremity injury in baseball players with various aspects of the pitching motion. To our knowledge, no study has directly evaluated the connection between maximum pitch velocity and elbow injury in professional baseball pitchers. Hypothesis Professional pitchers throwing at higher maximum ball velocity will have a higher risk of elbow injury. Study Design Cohort study; Level of evidence, 3. Methods Twenty-three professional pitchers were analyzed during spring training games and the ball velocity of the fastest pitch thrown for a strike (maximum pitch velocity) was recorded. This group was then followed prospectively over the following 3 seasons for elbow injury significant enough to warrant inclusion on the disabled list and/or require surgery. The association between maximum pitch velocity and elbow injury was then analyzed using an unpaired Student t test. Results There were 9 players with elbow injuries in the group of pitchers studied, including 4 pitchers with an elbow muscle strain and/or joint inflammation and 5 pitchers with an ulnar collateral ligament sprain or tear. Three of the ulnar collateral ligament injuries required surgery. For the 14 pitchers in the noninjured group, the mean pitch velocity was 38.09 m/s (±1.45) or 85.22 mph (±3.24). For the 9 players in the injured group, the mean pitch velocity was 39.88 m/s (±2.39) or 89.22 mph (±5.36). There was a statistically significant association between maximum ball velocity and elbow injury (P = .0354). The injured group had a longer average career length (9.7 years) than the noninjured group (6.5 years; P = .0248). The 3 pitchers with the highest maximum ball velocity had the injuries requiring surgery. Conclusion A statistically significant association between maximum pitch velocity and elbow injury was noted in this study, providing further support of existing theories about injury in baseball.
Tibial Cartilage Damage and Deformation at Peak Displacement Compression during Simulated Landing Impact
Authors: Yeow Chen Hua , Ng Yi Hao , Lee Peter Vee Sin , Goh James Cho Hong 
Published: January 2010

Background Structural changes of articular cartilage at the point of peak displacement compression during a landing impact are unknown. Hypothesis Extent of damage and deformation is significantly different for superficial, middle, and deep cartilage zones at peak displacement compression during simulated landing impact compared with after impact. Study Design Controlled laboratory study. Methods Explants were extracted from porcine tibial cartilages and divided into 3 test conditions: nonimpact control, impact and release, and impact and hold. Impact compression, with peak deformation of 2 mm, was applied based on a single 10-Hz haversine to simulate landing impact. For impact and release, explants were subjected to formalin fixation on removal of load after impact. For impact and hold, explants were immediately immersed in formalin with peak deformation maintained at 2 mm. After fixation, the explants underwent histology, whereby Mankin scores and cartilage thicknesses were obtained. Results Peak stresses of 9.8 to 28.1 MPa were noted during impact compression. For impact and release, substantial cartilage defects such as surface fraying and fissures were observed. For impact and hold, explants exhibited less severe matrix damage, such as superficial irregularities and tidemark disruption. Mankin scores were lower (indicating less damage; P < .05) in impact and hold than in impact and release condition. Superficial cartilage zone thickness was reduced (P < .05) in both impact and hold and impact and release conditions, relative to nonimpact control. Conclusion Not only does the loading phase of impact compression play a role in introducing substantial damage and deformation to cartilage, the unloading phase contributes to overall cartilage damage by exacerbating fissure propagation from surface lesions. Clinical Relevance Imaging of clinical injuries may underestimate the magnitude of cartilage compression that occurred during injury. Cartilage tissue engineering scaffolds must be designed to cope with the effects of loading and unloading phases, especially at the superficial zone, so that the repair site can function as well as does the neighboring native cartilage.
Cellular barcoding tool for clonal analysis in the hematopoietic system
Authors: Gerrits Alice , Dykstra Brad , Kalmykowa Olga J. , Klauke Karin , Verovskaya Evgenia , Broekhuis Mathilde J. C. , de Haan Gerald , Bystrykh Leonid V. 
Published: January 2010

AbstractClonal analysis is important for many areas of hematopoietic stem cell research, including in vitro cell expansion, gene therapy, and cancer progression and treatment. A common approach to measure clonality of retrovirally transduced cells is to perform integration site analysis using Southern blotting or polymerase chain reaction–based methods. Although these methods are useful in principle, they generally provide a low-resolution, biased, and incomplete assessment of clonality. To overcome those limitations, we labeled retroviral vectors with random sequence tags or “barcodes.” On integration, each vector introduces a unique, identifiable, and heritable mark into the host cell genome, allowing the clonal progeny of each cell to be tracked over time. By coupling the barcoding method to a sequencing-based detection system, we could identify major and minor clones in 2 distinct cell culture systems in vitro and in a long-term transplantation setting. In addition, we demonstrate how clonal analysis can be complemented with transgene expression and integration site analysis. This cellular barcoding tool permits a simple, sensitive assessment of clonality and holds great promise for future gene therapy protocols in humans, and any other applications when clonal tracking is important.
PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking
Authors: Vaid Ankush , Ranjan Ravikant , Smythe Wynand A. , Hoppe Heinrich C. , Sharma Pushkar 
Published: January 2010

AbstractPolyphosphorylated phosphoinositides (PIPs) are potent second messengers, which trigger a wide variety of signaling and trafficking events in most eukaryotic cells. However, the role and metabolism of PIPs in malaria parasite Plasmodium have remained largely unexplored. Our present studies suggest that PfPI3K, a novel phosphatidylinositol-3-kinase (PI3K) in Plasmodium falciparum, is exported to the host erythrocyte by the parasite in an active form. PfPI3K is a versatile enzyme as it can generate various 3′-phosphorylated PIPs. In the parasite, PfPI3K was localized in vesicular compartments near the membrane and in its food vacuole. PI3K inhibitors wortmannin and LY294002 were effective against PfPI3K and were used to study PfPI3K function. We found that PfPI3K is involved in endocytosis from the host and trafficking of hemoglobin in the parasite. The inhibition of PfPI3K resulted in entrapment of hemoglobin in vesicles in the parasite cytoplasm, which prevented its transport to the food vacuole, the site of hemoglobin catabolism. As a result, hemoglobin digestion, which is a source of amino acids necessary for parasite growth, was attenuated and caused the inhibition of parasite growth.
Interactions between flagellar and type III secretion proteins in Chlamydia pneumoniae
Authors: Stone Chris B , Bulir David C , Gilchrist Jodi D , Toor Raman K , Mahony James B 
Published: January 2010

Abstract

Background
Flagellar secretion systems are utilized by a wide variety of bacteria to construct the flagellum, a conserved apparatus that allows for migration towards non-hostile, nutrient rich environments. Chlamydia pneumoniae is an obligate, intracellular pathogen whose genome contains at least three orthologs of flagellar proteins, namely FliI, FlhA and FliF, but the role of these proteins remains unknown.

Results
Full length FliI, and fragments of FlhA, FliF, and FliI, were cloned and expressed as either GST or His tagged proteins in E. coli. The GST-tagged full length FliI protein was shown to possess ATPase activity, hydrolyzing ATP at a rate of 0.15 ± .02 μmol min-1 mg-1 in a time- and dose-dependant manner. Using bacterial-2-hybrid and GST pull-down assays, the N-terminal domain of FliI was shown to interact with the cytoplasmic domain of FlhA, but not with FliF, and the cytoplasmic domain of FlhA was shown to interact with the C-terminus of FliF. The absence of other flagellar orthologs led us to explore cross-reaction of flagellar proteins with type III secretion proteins, and we found that FliI interacted with CdsL and CopN, while FlhA interacted with CdsL and Cpn0322 (YscU ortholog CdsU).

Conclusions
The specific interaction of the four orthologous flagellar proteins in C. pneumoniae suggests that they interact in vivo and, taken together with their conservation across members of the chlamydiae sps., and their interaction with T3S components, suggests a role in bacterial replication and/or intracellular survival.
Tracing the origins of rescued chimpanzees reveals widespread chimpanzee hunting in Cameroon
Authors: Ghobrial Lora , Lankester Felix , Kiyang John A , Akih Akih E , de Vries Simone , Fotso Roger , Gadsby Elizabeth L , Jenkins Peter D , Gonder Mary K 
Published: January 2010

Abstract

Background
While wild chimpanzees are experiencing drastic population declines, their numbers at African rescue and rehabilitation projects are growing rapidly. Chimpanzees follow complex routes to these refuges; and their geographic origins are often unclear. Identifying areas where hunting occurs can help law enforcement authorities focus scarce resources for wildlife protection planning. Efficiently focusing these resources is particularly important in Cameroon because this country is a key transportation waypoint for international wildlife crime syndicates. Furthermore, Cameroon is home to two chimpanzee subspecies, which makes ascertaining the origins of these chimpanzees important for reintroduction planning and for scientific investigations involving these chimpanzees.

Results
We estimated geographic origins of 46 chimpanzees from the Limbe Wildlife Centre (LWC) in Cameroon. Using Bayesian approximation methods, we determined their origins using mtDNA sequences and microsatellite (STRP) genotypes compared to a spatial map of georeferenced chimpanzee samples from 10 locations spanning Cameroon and Nigeria. The LWC chimpanzees come from multiple regions of Cameroon or forested areas straddling the Cameroon-Nigeria border. The LWC chimpanzees were partitioned further as originating from one of three biogeographically important zones occurring in Cameroon, but we were unable to refine these origin estimates to more specific areas within these three zones.

Conclusions
Our findings suggest that chimpanzee hunting is widespread across Cameroon. Live animal smuggling appears to occur locally within Cameroon, despite the existence of local wildlife cartels that operate internationally. This pattern varies from the illegal wildlife trade patterns observed in other commercially valuable species, such as elephants, where specific populations are targeted for exploitation. A broader sample of rescued chimpanzees compared against a more comprehensive grid of georeferenced samples may reveal 'hotspots' of chimpanzee hunting and live animal transport routes in Cameroon. These results illustrate also that clarifying the origins of refuge chimpanzees is an important tool for designing reintroduction programs. Finally, chimpanzees at refuges are frequently used in scientific investigations, such as studies investigating the history of zoonotic diseases. Our results provide important new information for interpreting these studies within a precise geographical framework.
Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay
Authors: Fernandez-Becerra Carmen , Sanz Sergi , Brucet Marina , Stanisic Danielle I , Alves Fabiana P , Camargo Erney P , Alonso Pedro L , Mueller Ivo , del Portillo Hernando A 
Published: January 2010

AbstractBackgroundProgress towards the development of a malaria vaccine againstPlasmodium vivax, the most widely distributed human malaria parasite, will require a better understanding of the immune responses that confer clinical protection to patients in regions where malaria is endemic.MethodsGlutathioneS-transferase (GST) and GST-fusion proteins representing the N- terminus of the merozoite surface protein 1 ofP. vivax, PvMSP1-N, and the C-terminus, PvMSP1-C, were covalently coupled to BioPlex carboxylated beads. Recombinant proteins and coupled beads were used, respectively, in ELISA and Bioplex assays using immune sera ofP. vivaxpatients from Brazil and PNG to determine IgG and subclass responses. Concordances between the two methods in the seropositivity responses were evaluated using the Kappa statistic and the Spearman's rank correlation.ResultsThe results using this methodology were compared with the classical microtitre enzyme-linked immnosorbent assay (ELISA), showing that the assay was sensitive, reproducible and had good concordance with ELISA; yet, further research into different statistical analyses seems desirable before claiming conclusive results exclusively based on multiplex assays. As expected, results demonstrated that PvMSP1 was immunogenic in natural infections of patients from different endemic regions of Brazil and Papua New Guinea (PNG), and that age correlated only with antibodies against the C-terminus part of the molecule. Furthermore, the IgG subclass profiles were different in these endemic regions having IgG3 predominantly recognizing PvMSP1 in Brazil and IgG1 predominantly recognizing PvMSP1 in PNG.ConclusionsThis study validates the use of the multiplex assay to measure naturally-acquired IgG antibodies against the merozoite surface protein 1 ofP. vivax.
The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide
Authors: Carlsen Monica H , Halvorsen Bente L , Holte Kari , Bøhn Siv K , Dragland Steinar , Sampson Laura , Willey Carol , Senoo Haruki , Umezono Yuko , Sanada Chiho , Barikmo Ingrid , Berhe Nega , Willett Walter C , Phillips Katherine M , Jacobs David R , Blomhoff Rune 
Published: January 2010

Abstract

Background
A plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants. It has been hypothesized that plant antioxidants may contribute to the beneficial health effects of dietary plants. Our objective was to develop a comprehensive food database consisting of the total antioxidant content of typical foods as well as other dietary items such as traditional medicine plants, herbs and spices and dietary supplements. This database is intended for use in a wide range of nutritional research, from in vitro and cell and animal studies, to clinical trials and nutritional epidemiological studies.

Methods
We procured samples from countries worldwide and assayed the samples for their total antioxidant content using a modified version of the FRAP assay. Results and sample information (such as country of origin, product and/or brand name) were registered for each individual food sample and constitute the Antioxidant Food Table.

Results
The results demonstrate that there are several thousand-fold differences in antioxidant content of foods. Spices, herbs and supplements include the most antioxidant rich products in our study, some exceptionally high. Berries, fruits, nuts, chocolate, vegetables and products thereof constitute common foods and beverages with high antioxidant values.

Conclusions
This database is to our best knowledge the most comprehensive Antioxidant Food Database published and it shows that plant-based foods introduce significantly more antioxidants into human diet than non-plant foods. Because of the large variations observed between otherwise comparable food samples the study emphasizes the importance of using a comprehensive database combined with a detailed system for food registration in clinical and epidemiological studies. The present antioxidant database is therefore an essential research tool to further elucidate the potential health effects of phytochemical antioxidants in diet.