bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Crystal Structure, Thermal Expansion, Electrical Conductivity and Chemical Compatibility Studies of Nanocrystalline Ln0.6Sr0.4Co0.2Fe0.8 O3‐δ (Ln: Nd, Sm, Gd).
Authors: Chaubey Nityanand , Jain Dheeraj , Wani B. N. , Pillai C. G. S. , Bharadwaj S. R. , Chattopadhyaya M. C. 
Published: September 2011

AbstractThe title perovskite oxide based cathode materials are prepared by a gel‐combustion method from aqueous solutions of stoichiometric amounts of the metal nitrates using glycine as a fuel (sintering at 1673 K for 10 h).
ChemInform Abstract: Synthesis, Structure, and Magnetic Properties of the NaCoXO4F·2H2O Phases Where X: S and Se.
Authors: Melot B. C. , Chotard J.‐N. , Rousse G. , Ati M. , Reynaud M. , Tarascon J.‐M. 
Published: September 2011

AbstractCoSeO4 is prepared by neutralizing a solution of selenic acid with Co2(CO3)x(OH)y at 70 °C and used as precursor for the synthesis of NaCoSeO4F·2H2O by reaction with a stoichiometric amount of NaF at 80 °C.
ChemInform Abstract: Stereoselective Vinylogous Mukaiyama Aldol Reaction of α‐Haloenals.
Authors: Iwasaki Yoichi , Matsui Ryosuke , Suzuki Takahiro , Nakazaki Atsuo , Kobayashi Susumu 
Published: September 2011

AbstractA high yielding and stereoselective vinylogous Mukaiyama aldol reaction of α‐haloenals is developed.
ChemInform Abstract: Au(PPh3)OPOF2‐Catalyzed Intramolecular [4 + 2] Cycloaddition Reaction of Dienynes.
Authors: Kim Soo Min , Park Ji Hoon , Chung Young Keun 
Published: September 2011

AbstractA novel gold catalyst is described which is formed upon solvolysis of Au(PPh3)PF6 in the presence of traces of water.
ChemInform Abstract: Stereoselective Synthesis of Piperidinone and Quinolinone Systems via Ring Opening Reactions Using TiCl4/Silyl Reagents.
Authors: Muthusamy Sengodagounder , Gangadurai Chinnakuzhanthai , Krishnamurthi Janagiraman , Suresh Eringathodi 
Published: September 2011

AbstractThe Rh‐catalyzed treatment of diazoketones like (I) with imines of type (II) results in formation of oxa‐bridged piperidine ring systems such as (III) and (XI).
ChemInform Abstract: Stereoselective One‐Pot 1,4‐Elimination and the [1,2]‐Wittig Rearrangement of (E)‐δ‐(Arylmethoxy or 3‐Silyl‐2‐propynyloxy)‐Substituted Allylic Sulfones.
Authors: Horii Susumu , Ishimaru Isao , Ukaji Yutaka , Inomata Katsuhiko 
Published: September 2011

AbstractThe rearrangement of allylic sulfones induced by the successive treatment with KOtBu and LDA affords the corresponding dienyl alcohols with high selectivity for the formation of the respective (Z)‐isomer, due to a syn‐effect in the elimination step.
ChemInform Abstract: Inter‐ and Intramolecular Hydroacylation of Alkenes Employing a Bifunctional Catalyst System.
Authors: Vautravers Nicolas R. , Regent Damien D. , Breit Bernhard 
Published: September 2011

AbstractA novel bifunctional P,N‐ligand is synthesized and successfully used in rhodium‐catalyzed inter‐ and intramolecular hydroacylation reactions of alkenes.
ChemInform Abstract: Mild C—H Halogenation of Anilides and the Isolation of an Unusual Palladium(I)—Palladium(II) Species.
Authors: Bedford Robin B. , Haddow Mairi F. , Mitchell Charlotte J. , Webster Ruth L. 
Published: September 2011

AbstractRegioselective ortho‐halogenation of anilides (I), (III) is smoothly achieved with N‐halosuccinimides in the system Pd(O‐Ac)2—TosOH—air under mild conditions.
ChemInform Abstract: One‐Pot Synthesis of Salicylanilides by Direct Amide Bond Formation from Salicyclic Acid under Microwave Irradiation.
Authors: Lu Cheng‐Rong , Zhao Bei , Jiang Ying‐Peng , Ding Hao , Yang Sheng 
Published: September 2011

AbstractThe reaction is more efficient and wider in scope compared to established routes, moreover it provides short reaction times and convenient work‐up.
ChemInform Abstract: C—S Cross‐Coupling of Thiols with Aryl Iodides under Ligand‐Free Conditions Using Nano Copper Oxide as a Recyclable Catalyst in Ionic Liquid.
Authors: Schwab Ricardo S. , Singh Devender , Alberto Eduardo E. , Piquini Paulo , Rodrigues Oscar E. D. , Braga Antonio L. 
Published: September 2011

AbstractBest results are achieved performing the reaction in [bmmim]BF4.
ChemInform Abstract: Catalytic Asymmetric Conjugate Boration of α,β‐Unsaturated Sulfones.
Authors: Moure Abraham L. , Gomez Arrayas Ramon , Carretero Juan C. 
Published: September 2011

AbstractThe asymmetric boration of unsaturated sulfones (I) and (III) in the presence of optically active Cu(I)‐diphosphine complexes followed by oxidation of the addition products with NaBO3 leads to corresponding β‐hydroxysulfones (II) and (IV) with high enantioselectivity.
ChemInform Abstract: Highly Enantioselective Asymmetric Darzens Reactions with a Phase Transfer Catalyst.
Authors: Liu Yan , Provencher Brian A. , Bartelson Keith J. , Deng Li 
Published: September 2011

AbstractThe new PTC is used to catalyze an unprecedented highly enantioselective Darzens reaction of α‐chloro ketones with aldehydes to give optically active epoxides.
ChemInform Abstract: Tandem Cycloisomerization/Suzuki Coupling of Arylethynyl MIDA Boronates.
Authors: Chan Julian M. W. , Amarante Giovanni W. , Toste F. Dean 
Published: September 2011

AbstractThe process forms heterocyclic MIDA boronate intermediates which are directly coupled with aryl halides to give aryl‐substituted heterocycles.
ChemInform Abstract: Decarboxylative Formation of N‐Alkyl Pyrroles from 4‐Hydroxyproline.
Authors: Deb Indubhusan , Coiro Daniel J. , Seidel Daniel 
Published: September 2011

AbstractA new protocol for the synthesis of N‐alkylated pyrroles and related indoles via microwave‐accelerated decarboxylative condensation of corresponding N‐heterocyclic carboxylic acid with carbonyl compounds is presented.
ChemInform Abstract: Organocatalytic Asymmetric Conjugate Addition of α‐Substituted Cyanoacetates to Maleimides.
Authors: Wang Jin‐Jia , Dong Xue‐Jiao , Wei Wen‐Tao , Yan Ming 
Published: September 2011

AbstractChiral succinimides with two adjacent quaternary and tertiary stereogenic carbon centers are formed with good diastereo‐ and enantioselectivities in most cases using Takemoto′s thiourea catalyst.
ChemInform Abstract: Regioselective Synthesis of 3‐Substituted Pyrroles by Nucleophilic Addition of 3‐(1‐Arylsulfonylalkyl) Pyrroles Activated under Basic or Acid Conditions.
Authors: Martinelli Fabio , Palmieri Alessandro , Petrini Marino 
Published: September 2011

AbstractThe removal of the 3‐arylsulfonyl group of pyrroles can be achieved under basic or acidic conditions to give vinylogous imino‐like derivatives.
ChemInform Abstract: Carbohydrate‐Derived Alcohols as Organocatalysts in Enantioselective Aldol Reactions of Isatins with Ketones.
Authors: Shen Chao , Shen Fangyi , Xia Haijun , Zhang Pengfei , Chen Xinzhi 
Published: September 2011

AbstractGlucosamine‐derived compound GLU gives the resulting 3‐hydroxyindolinones with up to 75% enantioselectivities.
ChemInform Abstract: Synthesis, in vitro Antioxidant, Anthelmintic and Molecular Docking Studies of Novel Dichloro Substituted Benzoxazole‐triazolo‐thione Derivatives.
Authors: Satyendra R. V. , Vishnumurthy K. A. , Vagdevi H. M. , Rajesh K. P. , Manjunatha H. , Shruthi A. 
Published: September 2011

AbstractTriazolobenzoxazolethione (IV) and its derivatives (VI) and (IX) are synthesized from hydrazinylbenzoxazole (II) which is obtained by an anomalous reaction of hydrazine hydrate with ester (I).
ChemInform Abstract: Mg—Al Hydrotalcite as a First Heterogeneous Basic Catalyst for the Synthesis of 4H‐Pyrano[2,3‐c]pyrazoles Through a Four‐Component Reaction.
Authors: Kshirsagar Siddheshwar W. , Patil Nitin R. , Samant Shriniwas D. 
Published: September 2011

AbstractThe used heterogeneous catalyst Mg‐Al hydrotalcite can be easily removed from the reaction mixture by filtration.
ChemInform Abstract: Efficient Synthesis of 8‐Methoxy‐3,4‐dihydro‐2H‐1‐benzopyran‐3‐ol.
Authors: Shindikar A. V. , Viswanathan C. L. 
Published: September 2011

AbstractA practical, simple and inexpensive procedure for the preparation of title compound (VIII), a key intermediate in the synthesis of the β‐adrenoreceptor blocking agent nipradilol, is reported.
ChemInform Abstract: Palladium‐Catalyzed Regioselective Silaboration of Pyridines Leading to the Synthesis of Silylated Dihydropyridines.
Authors: Oshima Kazuyuki , Ohmura Toshimichi , Suginome Michinori 
Published: September 2011

AbstractDepending on the pyridine used, 1,4‐ or 1,2‐silaboration takes place.
ChemInform Abstract: 3‐(1,3,4‐Thiadiazole‐2‐yl)quinoline Derivatives: Synthesis, Characterization and Antimicrobial Activity.
Authors: Bhat Abdul R. , Tazeem Tazeem , Azam Amir , Choi Inho , Athar Fareeda 
Published: September 2011

AbstractA library of thiosemicarbazones (III) and thiadiazoles (V) is prepared with the aim to explore their effect on the growth of microorganisms.
ChemInform Abstract: Convenient Synthesis and Biological Activities of Pyridine Derivatives of 3,4‐Dihydropyrimidin‐2(1H)‐ones.
Authors: Zhu Xiao‐Fei , Shi De‐Qing 
Published: September 2011

AbstractTitle compounds of type (III) (9 examples) are prepared and screened for their biological activities.
ChemInform Abstract: Synthetic Studies on Erythrina Alkaloids: Formal Total Synthesis of (+)‐3‐Demethoxyerythratidinone.
Authors: Moon Jong Taik , Jung Jin Ah , Ha Sung Hoon , Song Sung Ho , Park Sung Jun , Kim Jungahn , Choo Dong Joon , Lee Yong Sup , Lee Jae Yeol 
Published: September 2011

AbstractThe title compound (+)‐(II) is synthesized from L‐malic acid.
ChemInform Abstract: Clausenawallines A and B, Two New Dimeric Carbazole Alkaloids from the Roots of Clausena wallichii.
Authors: Maneerat Wisanu , Ritthiwigrom Thunwadee , Cheenpracha Sarot , Prawat Uma , Laphookhieo Surat 
Published: September 2011

AbstractClausenawalline A (I) exhibits strong antimalarial activity, cytotoxicity and anti‐TB effects.
Visualisation research on characteristics of the cryogenic slug flow in vertical and inclined tubes
Authors: Liu Yi‐Peng , Wang Ping‐Yang , Hu Xue‐Yu , Zhang Hua , Du Zhao‐Hui 
Published: September 2011

AbstractThe statistical parameters of Taylor bubbles in cryogenic slug flow along glass tube were studied experimentally for various inclination angles θ (0°–60° from the vertical direction) and four tube inner diameters D (14, 18, 25 and 32 mm) by using high speed digital camera. The distributions and mean values of initial formation position, and the length and velocity of Taylor bubbles along the tube at various inclination angles were obtained. Initial position of Taylor bubbles increases as tube inner diameter increases and the effect of tube diameter on Taylor bubble initial position becomes more obvious at θ ≥ 30°. Taylor bubble length shows an allometric decreasing trend with the increasing of tube inner diameter. The influence of inclination angle and axial position on the length and velocity of Taylor bubble in cryogenic slug flow agrees qualitatively with conventional air–water system. The maximum mean velocity of Taylor bubble occurs at 30° ≤ θ ≤ 45° and the minimum mean length of Taylor bubble occurs at 0° ≤ θ ≤ 20°. The Mean length of Taylor bubble increases along the tube for x/D ≤ 60. © 2011 Canadian Society for Chemical Engineering
Pyrolysis kinetics of Athabasca bitumen using a TGA under the influence of reservoir sand
Authors: Murugan Pulikesi , Mani Thilakavathi , Mahinpey Nader , Dong Mingzhe 
Published: September 2011

AbstractPyrolysis kinetics of thermal decomposition of bitumen was investigated by thermogravimetric analysis (TGA). TGA experiments were conducted at multiple heating rates of 5, 10, 20°C min–1 up to 800°C to obtain the pyrolysis characteristics of bitumen. Weight loss curve from TGA shows that two different stages occurred during bitumen pyrolysis. Differential method has been used for determining the kinetic parameters and the best fit for the order of reaction was found based on the R2 values. Kinetics results confirm the presence of two different stages in bitumen pyrolysis with varying kinetic parameters. The average activation energy for the first and second stage was 29 and 60 kJ mol−1 and the average order of the reaction was 1.5 and 0.25, respectively. Experiments have been conducted with different reservoir sand. The effect of different source of sand reveals no effect on the pyrolysis behaviour of bitumen. A considerable difference was found with the pyrolysis of bitumen–sand mixtures and bitumen alone based on coke yield and activation energy. © 2011 Canadian Society for Chemical Engineering
Airway Gas Exchange and Exhaled Biomarkers
Authors: George Steven C. , Hlastala Michael P. 
Published: September 2011

AbstractDuring inspiration and expiration, gases traverse the conducting airways as they are transported between the environment and the alveolar region of the lungs. The term “conducting” airways is used broadly as the airway tree is thought largely to provide a conduit for the respiratory gases, oxygen and carbon dioxide. However, despite a significantly smaller surface area, and thicker barrier separating the gas phase from the blood when compared to the alveolar region, the airway tree can participate in gas exchange under special conditions such as high water solubility, high chemical reactivity, or production of the gas within the airway wall tissue. While these conditions do not apply to the respiratory gases, other gases demonstrate substantial exchange of the airways and are of particular importance to the inflammatory response of the lungs, the medical‐legal field, occupational health, metabolic disorders, or protection of the delicate alveolar membrane. Given the significant structural differences between the airways and the alveolar region, the physical determinants that control airway gas exchange are unique and require different models (both experimental and mathematical) to explore. Our improved physiological understanding of airway gas exchange combined with improved analytical methods to detect trace compounds in the exhaled breath provides future opportunities to develop new exhaled biomarkers that are characteristic of pulmonary and systemic conditions. © 2011 American Physiological Society.Compr Physiol1:1837‐1859, 2011.
Na+/H+Exchangers
Authors: Orlowski John , Grinstein Sergio 
Published: September 2011

AbstractTightly coupled exchange of Na+for H+occurs across the surface membrane of virtually all living cells. For years, the underlying molecular entity was unknown and the full physiological significance of the exchange process was not appreciated, but much knowledge has been gained in the last two decades. We now realize that, unlike most of the other transporters that specialize in supporting one specific function, Na+/H+exchangers (NHE) participate in a remarkable assortment of physiological processes, ranging from pH homeostasis and epithelial salt transport, to systemic and cellular volume regulation. In parallel, we have learned a great deal about the biochemistry and molecular biology of Na+/H+exchange. Indeed, it has now become apparent that exchange is mediated not by one, but by a diverse family of related yet distinct carriers (antiporters) sometimes present in different cell types and located in various intracellular compartments. Each one of these has unique structural features that dictate its functional role and mode of regulation. The biological relevance of Na+/H+exchange is emphasized by its evolutionary conservation; analogous exchangers are present from bacteria to man. Because of its wide distribution and versatile function, Na+/H+exchange has attracted an enormous amount of interest and therefore generated a vast literature. The vastness and complexity of the field has been compounded by the multiplicity of NHE isoforms. For reasons of space and in the spirit of this series, this overview is restricted to the family of mammalian NHEs. © 2011 American Physiological Society.Compr Physiol1:2083‐2100, 2011.
Membrane Proteins Structure and Dynamics by Nuclear Magnetic Resonance
Authors: Maltsev Sergey , Lorigan Gary A. 
Published: September 2011

AbstractMembrane proteins represent a challenging class of biological systems to study. They are extremely difficult to crystallize and in most cases they retain their structure and functions only in membrane environments. Therefore, commonly used diffraction methods fail to give detailed molecular structure and other approaches have to be utilized to obtain biologically relevant information. Nuclear magnetic resonance (NMR) spectroscopy, however, can provide powerful structural and dynamical constraints on these complicated systems. Solution‐ and solid‐state NMR are powerful methods for investigating membrane proteins studies. In this work, we briefly review both solution and solid‐state NMR techniques for membrane protein studies and illustrate the applications of these methods to elucidate proteins structure, conformation, topology, dynamics, and function. Recent advances in electronics, biological sample preparation, and spectral processing provided opportunities for complex biological systems, such as membrane proteins inside lipid vesicles, to be studied faster and with outstanding quality. New analysis methods therefore have emerged, that benefit from the combination of sample preparation and corresponding specific high‐end NMR techniques, which give access to more structural and dynamic information. © 2011 American Physiological Society.Compr Physiol1:2175‐2187, 2011.
The Ecohydrology of a pioneer wetland species and a drastically altered landscape
Authors: McLaughlin Daniel L. , Brown Mark T. , Cohen Matthew J. 
Published: September 2011

ABSTRACTVegetation plays a central role in forming and maintaining an ecosystem's physical conditions, which in turn strongly influence vegetation function. These bidirectional feedbacks may be particularly evident during an ecosystem succession following large‐scale disturbances. Clay settling areas (CSAs) are large elevated impoundments that receive clay slurry as a by‐product of phosphate mining in Florida. As CSAs mature, a limited seed source arrests ecological succession, resulting in the dominance of Salix caroliniana, which is likely further supported by altered abiotic conditions. The dominance of this wetland pioneer species and its interactions with soil and hydrology may largely determine the future ecosystem state. To identify how interactions between groundwater levels, soil water availability, and vegetation response regulate the succession of CSA ecosystems, we measured groundwater levels, vertical soil moisture profiles, soil water potentials, and root biomass allocation and transpiration of S. caroliniana at two sites. Fine soil texture in the CSAs resulted in capillary fringe heights greater than 1 m, which maintained soil moisture near saturation well above the water table. Rooting depths over 1 m in the clay soils provided sufficient water availability, which, along with high residual phosphorus concentrations, explained the dominance and high transpiration rates of S. caroliniana across CSAs. Capillary rise‐induced water availability created wetland soil conditions far upgradient from inundated areas, underscoring the role of soil texture in determining wetland extent. The strong coupling between water table and S. caroliniana transpiration, however, suggests that beyond soil development, this pioneer phreatophyte may also drive succession through systematic dewatering. Copyright © 2011 John Wiley & Sons, Ltd.
IL‐7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo
Authors: Pearson Claire , Silva Ana , Saini Manoj , Seddon Benedict 
Published: September 2011

AbstractThe cytokine interleukin (IL)‐7 is essential for Treg‐cell homeostasis. It remains unclear, however, whether IL‐7 regulates the homeostatic fitness of T cells quantitatively and, if so, by what mechanisms. We addressed this question by analysing T cells exposed to different levels of IL‐7 signalling in vivo. Using TCR transgenic mice that conditionally express IL‐7Rα, we show that T‐cell longevity in the absence of survival cues is not a cell‐intrinsic property but rather a dynamic process of which IL‐7 signalling is a key regulator. Naïve T cells deficient in IL‐7Rα expression underwent rapid cell death within hours of in vitro culture. In contrast, the same T cells from lymphopenic hosts, in which IL‐7 is non‐limiting, were able to survive in culture independently of growth factors for many days. Surprisingly, different levels of IL‐7 signalling in vivo evoked distinct molecular mechanisms to regulate homeostatic fitness. When IL‐7 was non‐limiting, increased survival was associated with up‐regulation of anti‐apoptotic Bcl2 family members. In contrast, in T‐cell replete conditions i.e. when IL‐7 is limiting, we found evidence that IL‐7 regulated T‐cell fitness by distinct non‐transcriptional mechanisms. Together, these data demonstrate a quantitative aspect to IL‐7 signalling dependent on distinct molecular mechanisms.
Pre‐differentiated human committed T‐lymphoid progenitors promote peripheral T‐cell re‐constitution after stem cell transplantation in immunodeficient mice
Authors: Eyrich Matthias , Schreiber Susanne C. , Wollny Gernot , Ziegler Hendrik , Schlenker Ramona , Koch‐Büttner Katharina , Wölfl Matthias , Schlegel Paul G. , Schilbach Karin 
Published: September 2011

AbstractT‐cell re‐constitution after allogeneic stem cell transplantation (alloSCT) is often dampened by the slow differentiation of human peripheral blood CD34+ (huCD34+) hematopoietic stem cells (HSCs) into mature T cells. This process may be accelerated by the co‐transfer of in vitro‐pre‐differentiated committed T/NK‐lymphoid progenitors (CTLPs). Here, we analysed the developmental potential of huCD34+ HSCs compared with CTLPs from a third‐party donor in a murine NOD‐scid IL2Rγnull model of humanised chimeric haematopoiesis. CTLPs (CD34+lin−CD45RA+CD7+) could be generated in vitro within 10 days upon co‐culture of huCD34+ or cord blood CD34+ (CB‐CD34) HSCs on murine OP9/N‐DLL‐1 stroma cells but not in a novel 3‐D cell‐culture matrix with DLL‐1low human stroma cells. In both in vitro systems, huCD34+ and CB‐CD34+ HSCs did not give rise to mature T cells. Upon transfer into 6‐wk‐old immune‐deficient mice, CTLPs alone did not engraft. However, transplantation of CTLPs together with huCD34+ HSCs resulted in rapid T‐cell engraftment in spleen, bone marrow and thymus at day 28. Strikingly, at this early time point mature T cells originated exclusively from CTLPs, whereas descendants of huCD34+ HSCs still expressed a T‐cell‐precursor phenotype (CD7+CD5+CD1a+/−). This strategy to enhance early T‐cell re‐constitution with ex vivo‐pre‐differentiated T‐lymphoid progenitors could bridge the gap until full T‐cell recovery in severely immunocompromised patients after allogeneic stem cell transplantation.