bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual Emission from Highly Conjugated 2,2′:6′:2″‐Terpyridine Complexes—A Potential Route to White Emitters
Authors: Siebert Ronald , Winter Andreas , Dietzek Benjamin , Schubert Ulrich S. , Popp Jürgen 
Published: March 2010

AbstractHere, we present a new class of terpyridine complexes of the transition‐metal ions, iron(II), ruthenium(II), and osmium(II), overcoming the poor emission properties typical for this class of polypyridyl complexes. These complexes show, besides an increased room‐temperature emission quantum yield and a prolonged lifetime of the metal‐to‐ligand charge‐transfer (MLCT) states, dual emission from two well‐separated excited states of the same molecule. These experimental findings are attributed to a highly stabilized ligand chromophore, where photoinduced excited‐state planarization causes an enhancement of electron delocalization. This planarization, in turn, reduces the potential energy of the S1 state and minimizes electronic coupling to the MLCT state, which is prone to non‐radiative deactivation via metal‐centered excited states. Due to their dual emission the complexes presented here show emission covering the entire Vis spectral range upon excitation of the ππ* states in the near UV. Thus, by structurally tuning the electronic coupling of the ππ* and the MLCT states a new synthetic route toward white emitters, which can subsequently be incorporated into polymers, is opened.magnified image
Returning to Basics: Direct Integration of the Full Molecular‐Weight Distribution Equations in Addition Polymerization
Authors: Saldívar‐Guerra Enrique , Infante‐Martínez Ramiro , Vivaldo‐Lima Eduardo , Flores‐Tlacuahuac Antonio 
Published: March 2010

AbstractDirect integration of the equations describing the full MWD in addition polymerization is shown to be feasible in reasonable computing times using standard computers for a considerable number of realistic systems. This is possible if the stiffness of the system is removed (if present) by the application of the QSSA, and the use of suitable numerical methods. This communication provides the basic ideas of a general method, based on the chemical nature of the system and the structure of the MWD equations. The application of the method provides additional insight on the dynamics and the underlying chemistry of the system. Examples of free radical polymerizations including controlled radical polymerization are offered, which can be solved in less than an hour on a PC.
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Reverse lateral supramalleolar adipofascial flap and skin grafting for one‐stage soft tissue reconstruction of foot and ankle joint
Authors: Lee Jae‐Hoon , Chung Duke‐Whan 
Published: March 2010

AbstractThe aim of this report is to present the clinical result and efficacy of reverse lateral supramalleolar adipofascial flap and skin grafting for one stage soft tissue reconstruction of the foot and ankle joints. Reconstruction using a reverse lateral supramalleolar adipofascial flap and skin grafting was performed in eight cases between January 2005 and March 2009. All the subjects were male with a mean age of 53 years. The mean follow‐up period was 20 months. The reasons for soft tissue defects were diabetic foot, infected bursitis, open injuries of the foot, and chronic osteomyelitis. The mean size of the flaps was 3.5 (3–4) × 4.5 (4–6) cm. The flaps were elevated in the form of an adipofascial flap and split‐thickness skin grafting was performed over the flaps and adjoining raw areas. Flaps survived in all cases. The implantation of the split‐thickness skin graft over the flap was also successful in all cases. Neither partial necrosis in the adipofascial flap nor venous congestion was observed. At the last follow‐up, there were no limited motions in the ankle and the toe. No cases complained of inconveniences in ambulation or had difficulties in selecting footwear. In cases that require a flap for the exposed bone or tendon of the foot with a small‐sized defect, reverse lateral supramalleolar adipofascial flap and skin grafting is considered a useful method as it lowers the morbidity rate of the donor site and reconstructs soft tissues. © 2010 Wiley‐Liss, Inc. Microsurgery 30:423–429, 2010.
Bioabsorbable device for small‐caliber vessel anastomosis
Authors: Ueda Kazunori , Mukai Tomokazu , Ichinose Shizuko , Koyama Yoshihisa , Takakuda Kazuo 
Published: March 2010

AbstractAlthough the devices for large‐caliber vessel (>2‐mm diameter) anastomosis are available, there are no devices for performing anastomosis of small‐caliber vessels. We designed a hooked device composed of a bioabsorbable polymer for sutureless anastomosis of small‐caliber vessels. The efficacy of this device was evaluated by in vitro degradation and arterial‐fixation strength tests as well as in vivo transplantation experiments with common carotid arteries of growing SD rats. A nonabsorbable device without hooks served as the control in the fixation strength and animal experiments. The tensile strength of the bioabsorbable device decreased to 27 and 9% of the initial value after 8‐ and 24‐week incubation, respectively. The fixation strength was greater and the anastomotic time was shorter with this device than with the control. The transplantation experiments showed complete endothelial bridging in both devices at 2 weeks after surgery (n = 6). The control device created a considerable protrusion into the arterial lumen at 8 postoperative weeks, whereas the experimental device did not (n = 6). Arterial diameter measurements detected a significant difference between the inner diameters at the respective anastomotic sites (n = 6, P < 0.05) and demonstrated that the control device hindered the vessel growth while the experimental device did not. Therefore, the bioabsorbable hooked device was an effective tool for anastomosis of small‐caliber arteries (ca. 1‐mm diameter). © 2010 Wiley‐Liss, Inc. Microsurgery 30:494–501, 2010.
Sticky platelet syndrome as a possible cause for free flap failure—A case report
Authors: Loeffelbein Denys John , Baumann Claudia Maria , Mücke Thomas , Wolff Klaus‐Dietrich , Hölzle Frank , Kesting Marco Rainer 
Published: March 2010

AbstractWe report a case of a patient who developed clinical symptoms of sticky platelet syndrome (SPS) during free microvascular flap transplantation, following resection of an oral tumor. Multiple arterial thromboses of two free tissue transfers occurred as a probable result of SPS. Diagnosis and treatment of the various forms of SPS are described. © 2010 Wiley‐Liss, Inc. Microsurgery 30:466–468, 2010.
Arterialized venous flaps: A review of the literature
Authors: Yan Hede , Brooks Darrell , Ladner Raven , Jackson William D. , Gao Weiyang , Angel Michael F. 
Published: March 2010

AbstractThe arterialized venous flaps are highly regarded in microsurgical and reconstructive surgeries based on advantages of ease of design and harvest without the need to perform deep dissection, no sacrifice of a major artery at the donor site, no limitation of the donor sites, and less donor‐site morbidity. Many experimental investigations and clinical applications have been reported. However, their survivals are still inconsistent, and survival mechanisms remain controversial. In this review, we update the existing problems, experimental studies for survival mechanisms, clinical practices, and methods developed to improve their survivals. © 2010 Wiley‐Liss, Inc. Microsurgery 30:472–478, 2010.
Chromium dinicocysteinate supplementation can lower blood glucose, CRP, MCP‐1, ICAM‐1, creatinine, apparently mediated by elevated blood vitamin C and adiponectin and inhibition of NFκB, Akt, and Glut‐2 in livers of zucker diabetic fatty rats
Authors: Jain Sushil K. , Croad Jennifer L. , Velusamy Thirunavukkarasu , Rains Justin L. , Bull Rebeca 
Published: March 2010

AbstractChromium and cysteine supplementation can improve glucose metabolism in animal studies. This study examined the hypothesis that a cysteinate complex of chromium is significantly beneficial than either of them in lowering blood glucose and vascular inflammation markers in Zucker diabetic fatty (ZDF) rats. Starting at the age of 6 wk, ZDF rats were supplemented orally (daily gavages for 8 more weeks) with saline‐placebo (D) or chromium (400 μg Cr/Kg body weight) as chromium dinicocysteinate (CDNC), chromium dinicotinate (CDN) or chromium picolinate (CP) or equimolar L‐cysteine (LC, img/Kg body weight), and fed Purina 5008 diet for 8 wk. ZDF rats of 6 wk age before any supplementations and onset of diabetes were considered as baseline. D rats showed elevated levels of fasting blood glucose, HbA1, CRP, MCP‐1, ICAM‐1 and oxidative stress (lipid peroxidation) and lower adiponectin and vitamin C, when compared with baseline rats. In comparison to D group, CDNC group had significantly lower blood glucose, HbA1, CRP, MCP‐1, ICAM‐1 and lipid peroxidation and increased vitamin C and adiponectin levels. CDN, CP or LC showed significantly less or no effect on these biomarkers. Only CDNC lowered blood creatinine levels in comparison to D. While CDN and CP had no effect, activation of NFκB, Akt and glucose transporter‐2 levels were decreased, insulin receptor substrate 1 (IRS‐1) activation increased in livers of CDNC‐rats. CDNC effect on glycemia, NFκB, Akt and IRS‐1 in liver was significantly greater compared with LC. Blood chromium levels did not differ between Cr‐groups. Exogenous vitamin C supplementation significantly inhibited MCP‐1 secretion in U937 monocytes cultured in high‐glucose‐medium. CDNC is a potent hypoglycemic compound with anti‐inflammatory activity apparently mediated by elevated blood vitamin C and adiponectin and inhibition of NFκB, Akt, and Glut‐2 and increased IRS‐1 activation in livers of type 2 diabetic rats.
Sesamin attenuates intercellular cell adhesion molecule‐1 expression in vitro in TNF‐α‐treated human aortic endothelial cells and in vivo in apolipoprotein‐E‐deficient mice
Authors: Wu Wen‐Huey , Wang Shu‐Huei , Kuan I‐I , Kao Ya‐shi , Wu Pei‐Jhen , Liang Chan‐Jung , Chien Hsiung‐Fei , Kao Chiu‐Hua , Huang Ching‐Jang , Chen Yuh‐Lien 
Published: March 2010

AbstractSesame lignans have antioxidative and anti‐inflammatory properties. We focused on the effects of the lignans sesamin and sesamol on the expression of endothelial‐leukocyte adhesion molecules in tumor necrosis factor‐α (TNF‐α)‐treated human aortic endothelial cells (HAECs). When HAECs were pretreated with sesamin (10 or 100 μM), the TNF‐α‐induced expression of intercellular cell adhesion molecule‐1 (ICAM‐1) was significantly reduced (35 or 70% decrease, respectively) by Western blotting. Sesamol was less effective at inhibiting ICAM‐1 expression (30% decrease at 100 μM). Sesamin and sesamol reduced the marked TNF‐α‐induced increase in human antigen R (HuR) translocation and the interaction between HuR and the 3'UTR of ICAM‐1 mRNA. Both significantly reduced the binding of monocytes to TNF‐α‐stimulated HAECs. Sesamin significantly attenuated TNF‐α‐induced ICAM‐1 expression and cell adhesion by downregulation of extracellular signal‐regulated kinase 1/2 and p38. Furthermore, in vivo, sesamin attenuated intimal thickening and ICAM‐1 expression seen in aortas of apolipoprotein‐E‐deficient mice. Taken together, these data suggest that sesamin inhibits TNF‐α‐induced extracellular signal‐regulated kinase/p38 phosphorylation, nuclear translocation of NF‐κB p65, cytoplasmic translocalization of HuR and thereby suppresses ICAM‐1 expression, resulting in reduced adhesion of leukocytes. These results also suggest that sesamin may prevent the development of atherosclerosis and inflammatory responses.
Vitamin D‐mediated calcium absorption in patients with clinically stable Crohn's disease: A pilot study
Authors: Kumari Meena , Khazai Natasha B. , Ziegler Thomas R. , Nanes Mark S. , Abrams Steven A. , Tangpricha Vin 
Published: March 2010

AbstractVitamin D is the critical hormone for intestinal absorption of calcium. Optimal calcium absorption is important for proper mineralization of bone in the prevention of osteoporosis and osteoporotic fractures, among other important functions. Diseases associated with gut inflammation, such as Crohn's disease (CD), may impair calcium absorption. This pilot study evaluated vitamin D‐ dependent calcium absorption in subjects with CD. Male subjects with CD (n=4) and healthy age‐matched controls (n=5) were studied. All subjects had fractional calcium absorption (FCA; by the dual calcium isotope method), serum 25‐hydroxyvitamin D, serum calcium and 24 h urinary calcium excretion measurements at baseline. The FCA in response to vitamin D therapy was re‐assessed following administration of oral calcitriol 0.25 mcg twice daily for 1 wk, followed by oral calcitriol 0.50 mcg twice daily for 1 wk. Serum calcium and 24 h urinary calcium determinations were re‐assessed after each increasing dose of calcitriol as safety measures. There was no significant difference in calcium FCA at baseline or after increasing doses of calcitriol between the CD and controls. FCA in the control and CD group was approximately 35% at baseline, which increased to 60% after calcitriol therapy. No subject developed hypercalcemia or hypercalciuria. Our results suggest that CD patients have a normal response to vitamin D in enhancing the efficacy of calcium absorption. This suggests that stable CD patients can follow calcium and vitamin D guidelines of non‐CD adults. Other factors independent of vitamin D status may impair intestinal calcium absorption in CD, including the degree and location of inflammation, presence of surgical resection and/or use of glucocorticoids.
Tocotrienols activity in MCF‐7 breast cancer cells: Involvement of ERβ signal transduction
Authors: Comitato Raffaella , Leoni Guido , Canali Raffaella , Ambra Roberto , Nesaretnam Kalanithi , Virgili Fabio 
Published: March 2010

AbstractThe term Vitamin E is utilized to describe eight molecules, subdivided into two groups, tocopherols and tocotrienols (TTs). It has been shown that specific TTs affect the growth of several lines of tumour cells, and that this activity is not shared by tocopherols. In agreement with these observations, a TTs‐rich fraction from palm oil (PTRF) was reported to inhibit proliferation and induce apoptosis in several cancer cells. However, the molecular mechanism involved in TTs activity is still unclear. We have recently proposed that TTs pro‐apoptotic activity involves estrogen receptor beta (ERβ) signalling. In this study, we report that, in MCF‐7 breast cancer cell, expressing both ERα and ERβ, PTRF treatment increases ERβ nuclear translocation, as demonstrated by immunofluorescence experiments and significantly inhibits ERα expression (−458.91‐fold of change) and complete disappearing of the protein from the nucleus. Moreover, PTRF treatment induces ER‐dependent genes expression (macrophage inhibitory cytokine‐1, early growth response‐1 and Cathepsin D) which is inhibited by the ER inhibitor, ICI 182.780, and induces DNA fragmentation. Finally, cDNA‐array experiments suggest that the activation of specific pathways in cells treated with γ‐TT with respect to α‐TT. Our data suggest a novel potential molecular mechanism for TTs activity.
Dietary phenolic acids attenuate multiple stages of protein glycation and high‐glucose‐stimulated proinflammatory IL‐1β activation by interfering with chromatin remodeling and transcription in monocytes
Authors: Wu Chi‐Hao , Yeh Chi‐Tai , Shih Ping‐Hsiao , Yen Gow‐Chin 
Published: March 2010

AbstractThis study examined the effects of dietary phenolic acids on individual stages of protein glycation and utilized monocyte cultures to assess whether these phytochemicals modulate the activation of proinflammatory cytokine under high glucose (HG, 15 mmol/L) conditions mimicking diabetes. In vitro glycation assays showed that a number of phenolic acids exerted inhibitory effects on the glycation reaction and its subsequent crosslinking. Phenolic acids, especially methoxyphenolic acids, prevented increase in both levels of the interleukin‐1β (IL‐1β) and oxidative stress caused by HG. The effect appeared to be mediated by modulation of the protein kinase C/nuclear factor‐κB axis. Chromatin immunoprecipitation demonstrated for the first time that HG increased the recruitment of nuclear factor‐κB p65 and CREB‐binding protein to the IL‐1β promoter. Interestingly, HG also increased histone acetylation and methylation within the IL‐1β promoter and decreased histone deacetylase activities in monocytes, thus facilitating chromatin remodeling and transcription. Such inappropriate inflammatory responses were found to be controlled effectively by treatment with methoxyphenolic compounds. In conclusion, this study suggests that phenolic acids could exert their anti‐inflammatory activities as antiglycation agents and as modifiers of signaling pathways. It provides evidence for a novel mechanism by which phenolics supplementation might have additional protective effects against diabetic complications.
Structure–affinity relationship of flavones on binding to serum albumins: Effect of hydroxyl groups on ring A
Authors: Xiao Jianbo , Cao Hui , Wang Yuanfeng , Yamamoto Koichiro , Wei Xinlin 
Published: March 2010

AbstractFour flavones (flavone, 7‐hydroxyflavone, chrysin, and baicalein) sharing the same B‐ and C‐ring structure but a different numbers of hydroxyl groups on the A‐ring were studied for their affinities for BSA and HSA. The hydroxylation on ring A of flavones increased the binding constants (Ka) and the number of binding sites (n) between flavones and serum albumins. The affinities of 7‐hydroxyflavone for BSA and HSA were about 800 times and 40 times higher than that of flavone, respectively. It appears that the optimal number of hydroxyl groups introduced to the ring A of flavones is one. As more hydroxyl groups were introduced to positions at C‐5, C‐6, and/or C‐7 of flavones, the affinities for serum albumins decrease. The critical energy transfer distances (R0) between the hydroxylated flavones (1–3 OH on the ring A) and serum albumins decreased with the increasing affinities for serum albumins.
Experimental characterization of a planar transmission‐line transformer in multilayered high dielectric constant film structure
Authors: Demenicis Luciene S. , Conrado Luiz Fernando M. , Margulis Walter , Carvalho Maria Cristina R. 
Published: March 2010

AbstractThis article describes the complete experimental characterization of a 10‐mm long planar transmission‐line transformer (TLT) in a multilayered high dielectric constant film structure. The multilayered configuration was obtained by deposition of a high dielectric constant BaTiO3(BTO) film over the conductors printed on conventional alumina bulk substrates. A transformation impedance level from 50 to 10 Ω could be achieved with comfortable transversal dimensions using this TLT. Frequency and time domain experimental results have confirmed theoretical predictions for this wideband compact device. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1337–1340, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25154
Evaluation of the effect of channel add/drop impact on power transients on the performance of a 10‐GB/S DWDM transmission system with hybrid EDFA/Raman amplification
Authors: Neto B. , Ferreira J. M. , Wada N. , Pinto A. N. , André P. S. 
Published: March 2010

AbstractWe experimentally assess the impact of the transient effect in the bit error rate of a 30 km 10 × 10 Gb/s DWDM transmission system with hybrid amplification.For that purpose, the analyzed hybrid system is composed by a counter‐pumped Raman fiber amplifier followed by an Erbium doped fiber preamplifier. The results show that the channels adding and drooping have a significant impact on the signal quality, in the worst case scenario a 8‐dB power penalty was obtained. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1225–1228, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25155
A printed antenna with constant gain over a wide bandwidth for ultra‐wideband applications
Authors: Ranga Y. , Esselle Karu P. , Weily A.R. , Verma A. K. 
Published: March 2010

AbstractA constant‐gain printed circular monopole antenna (PCMA) is presented that operates from 4 to 12 GHz. The gain of the PCMA is enhanced with the use of surface‐wave excited, proximity‐coupled (SW‐PC), conductor‐backed, twin‐slot radiators. A significant improvement in 2 and 3 dB peak gain bandwidth in the XY plane (θ = 90°) is achieved, and the peak measured gain of the antenna is nearly constant (5.5 dBi ± 1.5 dB) from 3 to 10 GHz. It has a very broad radiation pattern in the azimuth plane and a typical figure of eight pattern in the elevation plane. The antenna is also compact, robust, and easy to fabricate. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1261–1264, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25157
Insertion loss of lensed fiber collimator with larger gradient‐index lens diameter
Authors: Lin Yu‐Cheng 
Published: March 2010

AbstractThe insertion loss of lensed fiber collimator using gradient‐index fiber of 140‐μm diameter spliced to single‐mode fiber is investigated. The power transmission equation is applied for theoretical analysis of the insertion loss between a lensed fiber pair. Both numerical and experimental data are presented in axial and lateral displacement. The optimum coupling position 600 μm for 0.29‐pitch lensed fiber and the maximum working distance 1027 μm for 0.27‐pitch lensed fiber are demonstrated. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1235–1238, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25171
Synthesis of compact UWB bandpass filter with improved performances
Authors: Chen Chun‐Ping , Nihei Hiroshige , Ma Zhewang , Anada Tetsuo 
Published: March 2010

AbstractThis article presents a synthesis of the ultra‐wideband bandpass (UWB) filters consisting of two short‐circuited stubs combined with two stages of stepped impedance resonators (SIRs).The practical and theoretical transfer functions of the proposed UWB filters are derived. An example filter is firstly theoretically‐designed by the proposed synthesis procedure, then optimized by EM simulator, fabricated in microstrip line and finally characterized by a network analyzer. A good agreement between the theoretical and experimental results validates the proposed synthesis procedure successfully. In addition, the results of the designed filter show that the characteristics of the new filter is even better than those of a conventional filter composed of three‐stage of SIRs but without stubs. This means the proposed filters have compact sizes compared with the conventional ones. The designed filter also exhibits good characteristics of low insertion losses, quite sharp skirts, a flat group delay, deep attenuations in stopband (especially in lower one), and satisfies even FCC outdoor specifications. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1268–1271, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25172