bluuebunny/crossref_metadata_2025_split huggingface dataset:
Habitual sugar intake and cognitive function among middle-aged and older Puerto Ricans without diabetes
Authors: Ye Xingwang , Gao Xiang , Scott Tammy , Tucker Katherine L. 
Published: June 2011

Intake of added sugars, mainly fructose and sucrose, has been associated with risk factors for cognitive impairment, such as obesity, the metabolic syndrome and type 2 diabetes. The objective of this analysis was to examine whether habitual intakes of total sugars, added sugars, sugar-sweetened beverages or sweetened solid foods are associated with cognitive function. The present study included 737 participants without diabetes, aged 45–75 years, from the Boston Puerto Rican Health Study, 2004–9. Cognitive function was measured with a battery of seven tests: Mini-Mental State Examination (MMSE), word list learning, digit span, clock drawing, figure copying, and Stroop and verbal fluency tests. Usual dietary intake was assessed with a validated FFQ. Greater intakes of total sugars, added sugars and sugar-sweetened beverages, but not of sugar-sweetened solid foods, were significantly associated with lower MMSE score, after adjusting for covariates. Adjusted OR for cognitive impairment (MMSE score < 24) were 2·23 (95 % CI 1·24, 3·99) for total sugars and 2·28 (95 % CI 1·26, 4·14) for added sugars, comparing the highest with lowest intake quintiles. Greater intake of total sugars was also significantly associated with lower word list learning score. In conclusion, higher sugar intake appears to be associated with lower cognitive function, but longitudinal studies are needed to clarify the direction of causality.
Association of dietary energy density in childhood with age and body fatness at the onset of the pubertal growth spurt
Authors: Günther Anke L. B. , Stahl Lisa J. , Buyken Anette E. , Kroke Anja 
Published: June 2011

The aim of the present study was to examine the association of pre-pubertal dietary energy density (ED) with both age and body fatness at the start of the pubertal growth spurt (age at take-off, ATO). Analyses included 219 DOrtmund Nutritional and Anthropometric Longitudinally Designed Study participants with sufficient height measurements to estimate ATO who provided 3 d weighed dietary records at baseline, i.e. 2 and 3 years before ATO (mean age 6·9 (sd 1·2) years). Mean energy intakes and amounts of foods/drinks consumed at baseline were derived from the records. ED (kJ/g) was calculated based on (1) all foods and drinks (ED_all), (2) foods and energy-containing drinks (ED_energy), (3) foods and milk as a drink, but no other beverages (ED_milk) and (4) foods only, solid or liquid (ED_food). Using multiple regression analyses, the association between the ED variables and ATO was investigated. Furthermore, Z-scores of BMI and fat mass index (FMI) at ATO were considered as outcomes to reflect body fatness at puberty onset. The results showed that ED at baseline was not associated with ATO, regardless of the ED method used. For example, mean ATO in the lowest v. highest tertile of ED_food was 9·3 (95 % CI 9·0, 9·5) v. 9·4 (95 % CI 9·1, 9·7) years, Ptrend = 0·8 (adjusted for sex, maternal age, birth weight, dietary protein, dietary fibre, baseline BMI Z-score). Similarly, ED was not independently associated with BMI or FMI Z-score at ATO (Ptrend = 0·3–0·9). In conclusion, dietary ED in childhood did not influence timing or body fatness at ATO in this cohort of healthy, free-living children.
THE PARADOX OF LIMITED MAIZE STOVER USE IN INDIA'S SMALLHOLDER CROP-LIVESTOCK SYSTEMS
Authors: ERENSTEIN OLAF , SAMADDAR ARINDAM , TEUFEL NILS , BLÜMMEL MICHAEL 
Published: June 2011

SUMMARYCereal residues are an important feed source for ruminants in smallholder crop-livestock systems in the (sub)tropics. In many areas of India maize is a relatively new cash crop where farmers and development agents alike generally perceive maize stover to have limited utility, in contrast with the intensive feeding of other cereal residues in India and the intensive use of maize stover in sub-Saharan Africa and Latin America. A comparative assessment of maize stover quality (based on a brief review and a feeding trial) indeed confirms its potential as a ruminant feed according to its relative nutritive value. The paper then explores the apparent paradox through a scoping study of maize stover use (based on village surveys) in three contrasting maize-growing districts in India – including both traditional and non-traditional maize producers. The limited maize stover use appears to alleviate seasonal shortages, with tradition and technology helping explain the preferential use of other cereal residues. The paper thereby provides further impetus to India's apparent food-feed paradigm – whereby farmers’ staple food preferences coincide with crop residue feed preferences. The paper argues the case for investing in maize stover R&D in India and thus reigniting earlier feed research in general. Indeed, maize stover use is a relatively neglected area by India's agricultural R&D and merits more attention so as to exploit its potential contribution and alleviate eventual tradeoffs.
Neogene sediments and modern depositional environments of the Zagros foreland basin system
Authors: PIROUZ MORTAZA , SIMPSON GUY , BAHROUDI ABBAS , AZHDARI ALI 
Published: June 2011

AbstractA sedimentological investigation of the Neogene deposits of the Zagros foreland basin in SW Iran reveals a continuous and largely gradational passage from supratidal and sabkha sediments at the base (represented by the Gachsaran Formation) to carbonates and marine marls (Mishan Formation with basal Guri carbonate member) followed by coastal plain and meandering river deposits (Agha Jari Formation) and finally to braided river gravel sheets (Bakhtyari Formation). This vertical succession is interpreted to represent the southward migration of foreland basin depozones (from distal foredeep and foredeep to distal wedge-top and proximal wedge-top, respectively) as the Zagros fold–thrust belt migrated progressively southward towards the Arabian foreland. This vertical succession bears a striking similarity to modern depositional environments and sedimentary deposits observed in the Zagros region today, where one passes from mainly braided rivers in the Zagros Mountains to meandering rivers close to the coast, to shallow marine clastic sediments along the northern part of the Persian Gulf and finally to carbonate ramp and sabkha deposits along the southeastern coast of the Persian Gulf. This link between the Neogene succession and the modern-day depositional environments strongly suggests that the major Neogene formations of the Zagros foreland basin are strongly diachronous (as shown recently by others) and have active modern-day equivalents.
Firm Innovation in Emerging Markets: The Role of Finance, Governance, and Competition
Authors: Ayyagari Meghana , Demirgüç-Kunt Asli , Maksimovic Vojislav 
Published: June 2011

AbstractWe investigate the firm characteristics associated with innovation in over 19,000 firms across 47 developing economies. While existing finance literature on innovation is limited to large public firms in developed markets such as the United States, our database includes public and private firms, and small and medium-sized enterprises. We define innovation broadly to include introduction of new products and technologies, knowledge transfers, and new production processes. We find that access to external financing is associated with greater firm innovation. Further, having highly educated managers, ownership by families, individuals, or managers, and exposure to foreign competition is associated with greater firm innovation.
P-glycoproteins of Haemonchus contortus: development of real-time PCR assays for gene expression studies
Authors: Williamson S.M. , Wolstenholme A.J. 
Published: June 2011

AbstractP-glycoproteins (P-gps) are proteins that function as efflux pumps, removing lipophilic xenobiotic compounds from cells. There is evidence that P-gps play a role in the resistance of parasitic nematodes to anthelmintic drugs such as benzimidazoles and macrocyclic lactones. As anthelmintic resistance becomes more common, it is important to identify candidate resistance genes with the aim of understanding the molecular basis of resistance, and of developing assays to detect these resistance-associated changes. We identified several sequences from the genome of the parasite Haemonchus contortus with convincing homology to the known P-gp coding genes of the model nematode Caenorhabditis elegans. Nine of these sequences were successfully amplified by polymerase chain reaction (PCR) and shown to be most similar to the C. elegans sequences for pgp-1, pgp-2, pgp-3, pgp-4, pgp-9, pgp-10, pgp-11, pgp-12 and pgp-14. These partial P-gp sequences from H. contortus were used to design and optimize a quantitative real-time PCR assay to investigate potential changes in the expression levels of P-gp transcripts associated with drug resistance. No significant changes in P-gp mRNA expression levels were found in a rapidly selected ivermectin-resistant parasite isolate compared to its drug-sensitive parent, but the assay has the potential to be used on other isolates in the future to further investigate resistance-associated changes in P-gp gene expression.
Effect of relativistic self-focusing on plasma wave excitation by a hollow Gaussian beam
Authors: GUPTA RUCHIKA , RAFAT M. , SHARMA R. P. 
Published: June 2011

AbstractA paraxial-like approach has been invoked to understand the nature of propagation of a hollow Gaussian beam (HGB) propagating in plasma under the influence of relativistic non-linearity. In this approach, the parameters are expanded in terms of the radial distance from the maximum of irradiance rather than that from the axis. This paper investigates the excitation of plasma wave in a hot collision less plasma by HGB. On account of the × force, a plasma wave at 2ω0 (here, ω0 is the pump laser frequency) is generated. The solution of the HGB has been obtained within the paraxial ray approximation. Filamentary structures of the laser beam are observed due to relativistic non-linearity.
The structure of mental health research: networks of influence among psychiatry and clinical psychology journals
Authors: Haslam N. , Lusher D. 
Published: June 2011

BackgroundPsychiatry and clinical psychology are the two dominant disciplines in mental health research, but the structure of scientific influence and information flow within and between them has never been mapped.MethodCitations among 96 of the highest impact psychiatry and clinical psychology journals were examined, based on 10 052 articles published in 2008. Network analysis explored patterns of influence between journal clusters.ResultsPsychiatry journals tended to have greater influence than clinical psychology journals, and their influence was asymmetrical: clinical psychology journals cited psychiatry journals at a much higher rate than the reverse. Eight journal clusters were found, most dominated by a single discipline. Their citation network revealed an influential central cluster of ‘core psychiatry’ journals that had close affinities with a ‘psychopharmacology’ cluster. A group of ‘core clinical psychology’ journals was linked to a ‘behavior therapy’ cluster but both were subordinate to psychiatry journals. Clinical psychology journals were less integrated than psychiatry journals, and ‘health psychology/behavioral medicine’ and ‘neuropsychology’ clusters were relatively peripheral to the network.ConclusionsScientific publication in the mental health field is largely organized along disciplinary lines, and is to some degree hierarchical, with clinical psychology journals tending to be structurally subordinate to psychiatry journals.
Functional improvement and correlations with symptomatic improvement in adults with attention deficit hyperactivity disorder receiving long-acting methylphenidate
Authors: Buitelaar J. K. , Casas M. , Philipsen A. , Kooij J. J. S. , Ramos-Quiroga J. A. , Dejonckheere J. , van Oene J. C. , Schäuble B. 
Published: June 2011

BackgroundData on the relationship between core symptoms and daily functioning in adults with attention deficit hyperactivity disorder (ADHD) are limited. Daily functioning was assessed as part of an open-label extension, and associations with symptom scores were evaluated.MethodAfter a 5-week double-blind study with adults with ADHD receiving osmotic-controlled release oral delivery system (OROS) methylphenidate (MPH) 18, 36 or 72 mg/day, or placebo, participants were eligible for a 7-week open-label extension in which all patients received OROS MPH. Data for the Conners' Adult ADHD Rating Scale – Observer: Screening Version (CAARS-O:SV) (primary endpoint) have been presented previously. Secondary endpoints included the observer self-reported short version of the CAARS (CAARS-S:S) and the Clinical Global Impressions – Severity Scale (CGI-S). Daily functioning and quality of life were assessed using the Sheehan Disability Scale (SDS) and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) respectively. In post-hoc analyses, changes in CAARS-O:SV were evaluated in subgroups. Relationships between symptom and functional outcomes were evaluated in a multivariate regression analysis.ResultsA total of 370 patients entered the open-label extension. Significant improvements from baseline in CAARS-O:SV were similar regardless of sex, ADHD subtype, prior treatment or psychiatric co-morbidity. Significant improvements from double-blind baseline were also seen for the CAARS-S:S, CGI-S, SDS and Q-LES-Q. Improvements in the CAARS-O:SV Hyperactivity/Impulsivity subscale were associated with improvements in SDS total and subscale scores, and in the Q-LES-Q score at open-label endpoint. Improvements in CAARS-O:SV Inattention subscale and CGI-S scores were not significantly associated with functional changes.ConclusionsImprovements in ADHD symptoms relating to hyperactivity and impulsivity in adults receiving OROS MPH are associated with improvements in daily functioning and quality of life.
Cool and hot executive functions in medication-naive attention deficit hyperactivity disorder children
Authors: Yang B.-R. , Chan R. C. K. , Gracia N. , Cao X.-Y. , Zou X.-B. , Jing J. , Mai J.-N. , Li J. , Shum D. 
Published: June 2011

BackgroundThis study aimed to compare ‘cool’ [working memory (WM) and response inhibition] and ‘hot’ (delay aversion) executive functions (EFs) in children with and without attention deficit hyperactivity disorder (ADHD).MethodA total of 100 ADHD children (45 with family history of ADHD and 55 with no family history) and 100 healthy controls, all medication free, were tested on tasks related to the ‘hot’ (i.e. two choice-delay tasks) and ‘cool’ domains of EF (i.e. Digits backward, Corsi Block Task backward, Go/No-Go Task, Stop-Signal Task, and the Stroop).ResultsCompared with the controls, children with ADHD were found to perform significantly worse on one or more measures of response inhibition, WM, and delay aversion after controlling for co-morbidities and estimated IQ. In addition, comparisons between ADHD children with family history of ADHD and those with no family history found significant differences on measures of response inhibition and WM but not delay aversion. These results are largely supported by results of two logistic regressions.ConclusionsADHD was found to be associated with deficits on both cool and hot EFs. There is also evidence to suggest that cool EFs impairment is related to a family history of ADHD. Findings of this study have helped to elucidate the nature and extent of EF deficits in children with ADHD.
Specific language impairment at adolescence: Avoiding complexity
Authors: TULLER LAURICE , HENRY CÉLIA , SIZARET EVA , BARTHEZ MARIE-ANNE 
Published: June 2011

ABSTRACTThis study explores complex language in adolescents with specific language impairment (SLI) with the aim of finding out how aspects of language characteristic of typical syntactic development after childhood fare and, in particular, whether there is evidence that individuals with SLI avoid using structures whose syntactic derivation involves greater computational complexity. An analysis of spontaneous language samples of 18 French-speaking adolescents with SLI, compared to groups of typically developing speakers, showed that whereas complexity increases with age in the latter, behaviors of avoidance are clear in the former, in the form of low frequencies of complex structures, but also frequency of failed attempts and alternative strategies. Whereas increasing complexity is the hallmark of syntactic development after childhood, avoidance of complexity appears to characterize SLI after childhood.
Tense and aspect in childhood language impairment: Contributions from Hungarian
Authors: LEONARD LAURENCE B. , LUKÁCS ÁGNES , KAS BENCE 
Published: June 2011

ABSTRACTPrevious studies of children with language impairment (LI) reveal an insensitivity to aspect that may constitute part of the children's deficit. In this study, we examine aspect as well as tense in Hungarian-speaking children with LI. Twenty-one children with LI, 21 TD children matched for age, and 21 TD children matched for receptive vocabulary scores were tested on their comprehension and production of both imperfective and perfective verb forms in past tense contexts. Although the groups did not differ in their comprehension performance, the children with LI were less accurate than both comparison groups in producing both imperfective and perfective forms. Based on these results, it appears that children with LI have difficulties selecting the appropriate aspectual marking in past tense contexts.
Point to a referent, and say, “what is this?” Gesture as a potential cue to identify referents in a discourse
Authors: SO WING CHEE , LIM JIA YI 
Published: June 2011

ABSTRACTThis study explored whether caregivers' gestures followed the discourse-pragmatic principle of information status of referents (given vs. new) and how their children responded to those gestures when identifying referents. Ten Chinese-speaking and eight English-speaking caregivers were videotaped while interacting spontaneously with their children. Their speech and gestures were coded for referential expressions. Our findings showed that the Chinese-speaking caregivers gestured more often than the English-speaking caregivers but both of the groups gestured more often when asking their children to identify the new referents than the given referents (e.g., pointed to a puzzle while asking “What is this”?). The children were also sensitive to the information status of referents and they relied on the gestures to identify the new referents (but not the given referents). Overall, gesture serves as a potential cue for referential identification in both the caregivers and their children.
An Informant Questionnaire for Detecting Alzheimer's Disease: Are Some Items Better Than Others?
Authors: Sikkes Sietske A.M. , Knol Dirk L. , van den Berg Mark T. , de Lange-de Klerk Elly S.M. , Scheltens Philip , Klein Martin , Pijnenburg Yolande A.L. , Uitdehaag Bernard M.J. 
Published: June 2011

AbstractA decline in everyday cognitive functioning is important for diagnosing dementia. Informant questionnaires, such as the informant questionnaire on cognitive decline in the elderly (IQCODE), are used to measure this. Previously, conflicting results on the IQCODEs ability to discriminate between Alzheimer's disease (AD), mild cognitive impairment (MCI), and cognitively healthy elderly were found. We aim to investigate whether specific groups of items are more useful than others in discriminating between these patient groups. Informants of 180 AD, 59 MCI, and 89 patients with subjective memory complaints (SMC) completed the IQCODE. To investigate the grouping of questionnaire items, we used a two-dimensional graded response model (GRM).The association between IQCODE, age, gender, education, and diagnosis was modeled using structural equation modeling. The GRM with two groups of items fitted better than the unidimensional model. However, the high correlation between the dimensions (r=.90) suggested unidimensionality. The structural model showed that the IQCODE was able to differentiate between all patient groups. The IQCODE can be considered as unidimensional and as a useful addition to diagnostic screening in a memory clinic setting, as it was able to distinguish between AD, MCI, and SMC and was not influenced by gender or education. (JINS, 2011, 17, 674–681)
Dietary interventions for weight loss and cardiovascular risk reduction in people of African ancestry (blacks): a systematic review
Authors: Osei-Assibey G , Boachie C 
Published: June 2011

AbstractObjectiveTo systematically review weight and cardiovascular risk reduction in blacks by diet and lifestyle changes.DesignRandomised and non-randomised controlled trials of diet with/without lifestyle changes with duration of intervention ≥3 months, and published between January 1990 and December 2009, were searched in electronic databases including MEDLINE, EMBASE, CINAHL and CCTR (Cochrane Controlled Trials Register). Studies were included if they reported weight/BMI changes with changes in at least one of the following: systolic and diastolic blood pressure, fasting plasma lipids and glucose, and glycated haemoglobin.SettingClinical, community and church-based interventions.SubjectsStudy participants were of African ancestry (blacks).ResultsEighteen studies met the inclusion criteria. Average mean difference in weight loss was −2·66 kg, with improvements in all outcomes except total cholesterol. No significant difference was observed in outcome measures between all studies and studies that recruited only healthy participants or patients with type 2 diabetes.ConclusionsDiet and lifestyle changes result in weight loss with improvements in cardiovascular risk factors in blacks. However, more culturally tailored programmes have been suggested to motivate and encourage blacks to participate in intervention trials.
Nutritional policies and standards for snacks served in after-school programmes: a review
Authors: Beets Michael W , Tilley Falon , Kim YoungWon , Webster Collin 
Published: June 2011

AbstractObjectiveTo review and synthesize existing national and state organizations’ policies related to the nutritional quality of snacks served in after-school programmes (ASP; 15.00–18.00 hours) in the USA.DesignSystematic review of websites and corresponding documentation describing national and state-level ASP organizations’ policies, standards, guidelines and/or recommendations for the nutritional quality of snacks served within the ASP setting.SettingASP can play a critical role in a child's daily dietary intake. State and national organizations have developed policies to assist ASP in selecting nutritionally appropriate snacks, yet no widely accepted standards exist. By reviewing the extent of existing policies, recommendations for uniform policies can be made.SubjectsPolicy documentation.ResultsA total of seventeen organizations representing five unique snack policies comprised of thirteen different food items were identified. The most widely recognized snack policy, which the majority of state and national ASP organizations endorsed and upon which other snack policies were modelled, was the US Department of Agriculture reimbursement programmes. Consistently, policies endorsed serving fruits/vegetables, whole grains and milk/dairy products, and limiting foods high in fats/sugar/energy (calories). Two policies focused predominantly on total energy and macronutrient composition of snacks, a single policy suggested limits on sugar-sweetened beverages, and three endorsed serving water daily. A proposed set of general guidelines for ASP was developed based on uniformity in recommendations across policies.ConclusionsThe proposed set of nutritional guidelines will assist policy makers and ASP providers in selecting and serving nutritionally appropriate snacks that contribute to a child's overall healthful daily dietary intake.