bluuebunny/crossref_metadata_2025_split huggingface dataset:
Angiographic morphology impacts outcomes in STEMI patients with LAD occlusion
Authors: Arinell Karin , Josefsson Johan , Magnuson Anders , Fröbert Ole 
Published: April 2010

AbstractObjectives and background: Acute proximal occlusion of the left anterior descendent coronary artery (LAD) is a critical medical condition often leading to heart failure and death. Our objective was to investigate how additional angiographic findings might influence prognosis. Methods: In a single center setting by using consecutive data from the Swedish angiography and angioplasty registry (SCAAR), we identified all patients with acute myocardial infarction (AMI) related to the proximal LAD referred for primary coronary angioplasty. Clinical and angiographic data were collected from January 2004 to December 2008. Results: In the study period, 359 patients (mean age 67.9 ± 12.3 years, 111 women) were identified as having proximal LAD‐related culprit lesion. Follow‐up was up to 5.5 years. Compared to patients with LAD occlusion only, having both a small conus branch (<0.5 mm in diameter) and an occluded first septal perforator was associated with increased risk of death after adjustment for age, diabetes mellitus and prior AMI (hazard ratio 4.5, 95% CI; 1.1–18, P = 0.033). A small conus branch in itself was not important. Multivessel coronary artery disease in addition to occlusion of the first septal perforator branch and having a small conus branch was also associated with increased risk of death (hazard ratio 5.2, 95% CI; 1.3–20), P = 0.018). Conclusions: In patients with STEMI because of a proximal LAD lesion treated by primary PCI, the combination of a small conus branch and an occluded first septal perforator branch is associated with a poorer outcome. Additional presence of multivessel coronary artery disease further aggravates outcome. © 2010 Wiley‐Liss, Inc.
Late coronary complications after arterial switch operation and their treatment
Authors: El‐Segaier Milad , Lundin Anders , Hochbergs Peter , Jögi Peeter , Pesonen Erkki 
Published: April 2010

AbstractObjectives: To report the late coronary complications and their treatment after arterial switch operation (ASO). Background: Asymptomatic patients after ASO may have coronary ostial stenosis or obstruction. Methods: Since 1980, 279 patients were operated with ASO. At the time of preparing this article, selective follow‐up coronary angiograms were done on 81 patients. Results: Coronary stenosis was found in six patients. A 6‐year‐old patient with left coronary artery (LCA) ostial stenosis and a 9‐year‐old patient with conus branch occlusion had good collaterals without a need for further treatment. One patient with LCA obstruction, myocardial infarction, and left ventricular failure was operated with osteoplasty at age of 16 years. In three essentially asymptomatic patients, stenting of LCA ostium stenosis was done: in two of them with drug‐eluting stents at 9 and 10 years of age and in one with bare‐metal stent at 18 years of age. One of these patients was earlier treated with balloon dilatation at 5 years of age which caused intimal dissection. Conclusions: Asymptomatic patients with an uneventful course after ASO may have coronary obstruction. This necessitates follow‐up coronary evaluation in all patients. Stenting of the coronary arteries is an option for treatment. © 2010 Wiley‐Liss, Inc.
A novel catheter in patients with peripheral chronic total occlusions: A single center experience
Authors: Khalid M. Rizwan , Khalid Fatima R. , Farooqui F. Ali , Devireddy Chandan M. , Robertson Gregory C. , Niazi Khusrow 
Published: April 2010

AbstractObjectives and Background: Recanalization of a chronic total occlusion (CTO) is technically challenging with less than optimum results in arterial disease. Crosser® is a novel technology that utilizes high frequency (20 KHz) vibration energy to fragment occlusive fibrous atherosclerotic plaque and helps in traversing the occluded vessel. We report a single center experience with this catheter as the primary device in peripheral chronic total occlusions. Methods: The catheter was used as the primary device in 25 consecutive patients with peripheral CTOs. The peripheral CTOs in this study are defined as 100% occluded vessels involving any segment of the iliac artery or below the inguinal ligament down to the trifurcation vessels which have been occluded for greater than 3 months judged by patient's history of longstanding symptoms with no worsening in the past 3 months. Procedural success was defined by the ability of the device to facilitate guide wire crossing of the occlusion. All angiograms were evaluated by two operators. Data on demographics, angiographic variables, and patient complications was collected. Results: The device was used in 25 consecutive patients and 27 CTO lesions were treated. Critical limb ischemia and claudication were the indications in 32 and 68% of the patients, respectively. Average lesion length was 117 mm (range 10–300 mm). Superficial femoral artery was the most common lesion site (n = 20, 74%). Crosser‐assisted guide wire recanalization was achieved in 11(41%) lesions while the final overall procedure success rate with any device was 63% (n = 17). Perforation occurred in five lesions with one directly attributable to this device. Conclusions: In this single center observational review, the Crosser device in peripheral CTO lesions had a procedural success of 41%. © 2010 Wiley‐Liss, Inc.
Repeat percutaneous mitral balloon valvuloplasty for patients with mitral valve restenosis
Authors: Chmielak Zbigniew , Klopotowski Mariusz , Kruk Mariusz , Demkow Marcin , Konka Marek , Chojnowska Lidia , Hoffman Piotr , Witkowski Adam , Ruzyllo Witold 
Published: April 2010

AbstractObjectives: To determine immediate and long‐term clinical outcome, as well prognostic factors in patients who underwent repeat percutaneous mitral balloon valvuloplasty (PMBV). Background: Repeat PMBV may be a method of treatment for symptomatic patients with restenosis after successful initial PMBV, but data regarding its long term safety and efficacy are scarce. Methods: The study group consisted of 67 patients (mean age 52.1 ± 10.5 years). All PMBV procedures were performed using the Inoue balloon system. Results: Repeat PMBV resulted in significant increase in MVA from 1.17 ± 0.16 cm2 to 1.63 ± 0.22 cm2 (P < 0.001). Good immediate result (MVA ≥1.5 cm2, mitral regurgitation ≤2) was obtained in 52 (77.6%) patients and was not predicted by any analyzed factors. During follow‐up (mean time 4.9 ± 2.9 years) six patients died, nine underwent mitral valve replacement, four—third PMBV, and four developed heart failure. The 3‐, 5‐, and 8‐year good functional results (survival free of mitral valve replacement, third PMBV or heart failure ≥ NYHA III) by Kaplan–Meier estimates were 89.3, 75.6, and 52.6%, respectively. These results were significantly superior in patients with good immediate results and echo score <7. In the entire population multivariate Cox regression analysis identified echo score <7 and absence of prior surgical commissurotomy as the independent predictors of event‐free survival. Conclusions: Repeat PMBV is safe and provides good immediate results in patients with restenosis after successful first procedure. Long‐term results of repeat PMBV are satisfactory and related mainly to the echo score and quality of the procedure. © 2010 Wiley‐Liss, Inc.
Entrapment of an arterial pressure catheter by a previously deployed starclose device
Authors: Alameddine Abdallah K. , Rousou John A. 
Published: April 2010

AbstractHerein is a case report description of entrapment of an arterial pressure line by a previously deployed Starclose device. This device is widely used to control femoral artery puncture site following diagnostic catheterization. © 2010 Wiley‐Liss, Inc.
Electron Localization Dynamics in the Triplet Excited State of [Ru(bpy)3]2+ in Aqueous Solution
Authors: Moret Marc‐Etienne , Tavernelli Ivano , Chergui Majed , Rothlisberger Ursula 
Published: April 2010

AbstractHybrid DFT/classical molecular dynamics of the long‐lived triplet excited state of [Ru(bpy)3]2+ (bpy=2,2′‐bipyridine) in aqueous solution is used to investigate the solvent‐mediated electron localization and dynamics in the triplet metal‐to‐ligand charge‐transfer (MLCT) state. Our studies reveal a solvent‐induced breaking of the coordination symmetry with consequent localization of the photoexcited electron on one or two bipyridine units for the entire length of our simulation, which amounts to several picoseconds. Frequent electronic “hops” between the ligands constituting the pair are observed with a characteristic time of approximately half a picosecond.
High‐yield Synthesis of Branched Gold Nanocrystals by a Sodium Diphenylamine‐4‐Sulfonate Reduction Process in Polyethylene Glycol Aqueous Solution
Authors: Liu Qi , Lai Lifang , Huang Hexiang , Sun Jianhua , Shang Tongming , Zhou Quanfa , Xu Zheng 
Published: April 2010

AbstractFor developing new excellent electrocatalysts toward methanol and oxygen, branched Au nanocrystals have been prepared in high yield by the reaction of HAuCl4 and sodium diphenylamine‐4‐sulfonate in the presence of PEG (polyethylene glycol) at room temperature. When the amount of PEG was in the range of 1–3 mL, branched Au nanocrystals were all obtained, and the amounts of sodium diphenylamine‐4‐sulfonate and HAuCl4 had no obvious effect on the morphology of gold nanocrystals. PEG molecules play an important role in the formation of branched gold nanocrystals. The nanocrystals were characterized by transmission electron microscopy (TEM), selected area electron diffraction, high‐resolution transmission electron microscopy (HRTEM) and UV‐Vis absorption spectrum. HRTEM research suggests that the tips of gold nanocrystals grow selectively in the [111] directions. The UV‐Vis absorption spectrum displays two‐separated surface plasmon resonance peaks.
Synthesis and Adsorption Performance of Surface‐Grafted Co(II)‐Imprinted Polymer for Selective Removal of Cobalt
Authors: Liu Yan , Gao Jie , Li Chunxiang , Pan Jianming , Yan Yongsheng , Xie Jimin 
Published: April 2010

AbstractThe surface‐grafting ion‐imprinting technology was applied to synthesis of a new Co(II)‐imprinted polymer [Co(II)‐IP], which could be used for selective removal of Co(II) from aqueous solutions. The prepared polymer was characterized by using the infrared spectra (IR), X‐ray diffractometer (XRD), X‐ray energy dispersion spectroscopy (EDS) and scanning electron microscopy (SEM). The maximum adsorption capacity values for the Co(II)‐imprinted polymer and non‐imprinted polymer (NIP) were 22 and 8 mg/g, respectively. The Freundlich equation fitted the adsorption isotherm data well. The applicability of two kinetic models including pseudo‐first‐order and pseudo‐second‐order models was estimated on the basis of comparative analysis of the corresponding rate parameters, equilibrium capacity, and correlation coefficients. Results suggested that chemical process could be the rate‐limiting step in the adsorption process. And the adsorption of Co(II) on the Co(II)‐imprinted polymer was endothermic. The relative selectivity coefficients of the Co(II)‐imprinted polymer for Co(II)/Pb(II), Co(II)/Cu(II), Co(II)/Ni(II), Co(II)/Sr(II) and Co(II)/Cs(I) were respectively 11.5, 6.1, 13.8, 9.4, and 8.1 times greater than that of the non‐imprinted polymer. Eventually, the desorption conditions of the adsorbed Co(II) from the Co(II)‐imprinted polymer were also studied in batch experiments.
Structural Characterization and Thermal Behavior of 1‐Amino‐1‐methylamino‐2,2‐dinitroethylene
Authors: Xu Kangzhen , Wang Feng , Ren Yinghui , Li Wenhong , Zhao Fengqi , Chang Chunran , Song Jirong 
Published: April 2010

AbstractA novel high energetic material, 1‐amino‐1‐methylamino‐2,2‐dinitroethylene (AMFOX‐7), was synthesized through 1,1‐diamino‐2,2‐dinitroethylene (FOX‐7) reacting with methylamine in N‐methyl pyrrolidone (NMP) at 80.0°C, and its structure was determined by single crystal X‐ray diffraction. The crystal is monoclinic, space group P21/m with crystal parameters of a=6.361(3) Å, b=7.462(4) Å, c=6.788(3) Å, β=107.367(9)°, V=307.5(3) Å3, Z=2, µ=0.160 mm−1, F(000)=168, Dc=1.751 g·cm−3, R1=0.0463 and wR2=0.1102. Thermal decomposition of AMFOX‐7 was studied, and the enthalpy, apparent activation energy and pre‐exponential constant of the exothermic decomposition reaction are 303.0 kJ·mol−1, 230.7 kJ·mol−1 and 1021.03 s−1, respectively. The critical temperature of thermal explosion is 245.3°C. AMFOX‐7 has higher thermal stability than FOX‐7.
Thiadiazole‐based Thioglycosides as Sodium‐glucose Co‐transporter 2 (SGLT2) Inhibitors
Authors: Gao Yunlong , Zhao Guilong , Liu Wei , Wang Yuli , Xu Weiren , Wang Jianwu 
Published: April 2010

AbstractA series of thiadiazole‐based thioglycosides were synthesized as SGLT2 inhibitors from D‐glucose, D‐galactose and a variety of phenylacetic acids via a convenient protocol in 8 steps and evaluated in vivo with an oral glucose tolerance test (OGTT), and 5‐benzyl‐1,3,4‐thiadiazol‐2‐yl 1‐thio‐β‐D‐glucopyranoside (1a) was the most efficacious to suppress the blood glucose excursion during OGTT.
Impact of weekend admissions on quality of care and outcomes in patients with acute myeloid leukemia
Authors: Bejanyan Nelli , Fu Alex Z. , Lazaryan Aleksandr , Fu Rao , Kalaycio Matt , Advani Anjali , Sobecks Ronald , Copelan Edward , Maciejewski Jaroslaw P. , Sekeres Mikkael A. 
Published: April 2010

AbstractBACKGROUND:Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekdays and treated with induction chemotherapy.METHODS:This retrospective follow‐up study involved 422 AML patients treated with cytarabine‐based induction chemotherapy at Cleveland Clinic from 1994‐2008. Quality outcome measures included time to triple‐lumen catheter (TLC) placement, time to induction chemotherapy, length of stay (LOS), early death (within 15 days of chemotherapy), and 30‐day mortality. These were tested for the association with known predictors of AML survival and etiology by the methods of linear, categorical, and survival analyses.RESULTS:Twenty‐three percent of all admissions (n = 422) occurred over the weekend (n = 103). Compared with younger (aged <60 years) patients, older patients had higher 30‐day mortality (P = .003), early death (P = .025), and time to induction rates (P = .02), but lower complete remission (P = .001) and overall survival (OS) rates (P < .0001). In univariate analyses, time to TLC was delayed for weekend admissions (P < .01). Weekend admissions had lower early mortality (P = .04) and 30‐day mortality (P = .02). In multivariate analysis, only time to TLC remained significantly longer for weekend admissions (P < .001).CONCLUSIONS:Weekend admissions significantly delayed placement of TLC without affecting other quality parameters or patient survival. This is likely because of immediate initiation of peripheral chemotherapy with cytarabine even before the placement of TLC for infusion of anthracyclines. Cancer 2010. © 2010 American Cancer Society.
The culture of faith and hope
Authors: Sulmasy Daniel P. , Astrow Alan B. , He M. Kai , Seils Damon M. , Meropol Neal J. , Micco Ellyn , Weinfurt Kevin P. 
Published: April 2010

AbstractBACKGROUND:Patients' estimates of their chances of therapeutic benefit from participation in early phase trials greatly exceed historical data. Ethicists worry that this therapeutic misestimation undermines the validity of informed consent.METHODS:The authors interviewed 45 patients enrolled in phase 1 or 2 oncology trials about their expectations of therapeutic benefit and their reasons for those expectations. They used a phenomenological, qualitative approach with 1 primary coder to identify emergent themes, verified by 2 independent coders.RESULTS:Median expectations of therapeutic benefit varied from 50% to 80%, depending on how the question was asked. Justifications universally invoked hope and optimism, and 27 of 45 participants used 1 of these words. Three major themes emerged: 1) optimism as performative, that is, the notion that positive thoughts and expressions improve chances of benefit; 2) fighting cancer as a battle; and 3) faith in God, science, or both. Many participants described a culture in which optimism was encouraged and expected, such that trial enrollment became a way of reflecting this expectation. Many reported they had been told few patients would benefit and appeared to understand the uncertainties of clinical research, yet expressed high expected personal therapeutic benefit. More distressed participants were less likely to invoke performative justifications for their expectations (50% vs 84%; P = .04).CONCLUSIONS:Expressions of high expected therapeutic benefit had little to do with reporting knowledge and more to do with expressing optimism. These results have implications for understanding how to obtain valid consent from participants in early phase clinical trials. Cancer 2010. © 2010 American Cancer Society.
Colour psychology and colour therapy: Caveat emptor
Authors: O'Connor Zena 
Published: April 2010

AbstractInformation about colour psychology and colour therapy abounds in popular culture. Articles found in mass media as well as a plethora of Internet websites are often devoted to colour and a range of psychological, biological, and behavioral effects. The information available, which varies from scant summaries with catchy titles to lengthy and comprehensive discussions, is often presented in an authoritative manner exhorting the reader to believe a range of claims such as red is physically stimulating and arousing and blue is calming, relaxing and healing. However, empirical evidence or evidence of any nature is only rarely cited and, when it is, it's often in reference to findings that are inappropriately generalized or out‐of‐date and superseded. This article discusses a range of colour psychology and colour therapy claims found in popular culture and notes the similarities between these claims and the writings of early theorists such as Birren, Goldstein, Gerard and Luscher. While these authors have a valid if somewhat dated place in the literature on colour, there are a number of key reasons to be wary of colour psychology and colour therapy claims made in popular culture. These reasons are discussed in some detail and provide compelling support for applying the caveat emptor principle to colour psychology and colour therapy claims found in nonacademic sources. © 2010 Wiley Periodicals, Inc. Col Res Appl, 36, 229–234, 2011;
Hydrogen Production over Titania‐Based Photocatalysts
Authors: Leung Dennis Y. C. , Fu Xianliang , Wang Cuifang , Ni Meng , Leung Michael K. H. , Wang Xuxu , Fu Xianzhi 
Published: April 2010

AbstractBecause of their relatively high efficiency, high photostability, abundance, low cost, and nontoxic qualities, titania‐based photocatalysts are still the most extensively studied materials for the photocatalytic production of hydrogen from water. The effects of the chemical and physical properties of titania, including crystal phase, crystallinity, particle size, and surface area, on its photoactivity towards hydrogen generation have been identified by various investigations. The high overpotential for hydrogen generation, rapid recombination of photogenerated electrons and holes, rapid reverse reaction of molecular hydrogen and oxygen, and inability to absorb visible light are considered the most important factors that restrict the photoactivity of titania, and strategies to overcome these barriers have been developed. These issues and strategies are carefully reviewed and summarized in this Minireview. We aim to provide a critical, up‐to‐date overview of the development of titania‐based photocatalysts for hydrogen production, as well as a comprehensive background source and guide for future research.
Reactive power compensation in a multi‐line system under sinusoidal unbalanced conditions
Authors: Jeon Seong‐Jeub , Willems Jacques L. 
Published: April 2010

AbstractA new generalized reactive power compensation algorithm applicable to a multi‐line system under sinusoidal conditions is reviewed. This method does not require any decomposition of reactive power or non‐active current. It is shown that a realization of the compensator can be obtained by means of a simple connection of reactive elements. Accordingly, it is concluded that to compensate the reactive power is a simple circuit synthesis problem. The algorithm is illustrated by means of examples. Copyright © 2010 John Wiley & Sons, Ltd.
Repeater insertion in crosstalk‐aware inductively and capacitively coupled interconnects
Authors: Kaushik Brajesh Kumar , Agarwal Rajendra P. , Sarkar Sankar , Joshi Ramesh C. , Chauhan D. S. 
Published: April 2010

AbstractThis paper reveals that repeater insertion not only reduces propagation delay but also reduces crosstalk level in coupled interconnects. Repeaters can therefore be efficiently utilized for reduction in propagation delay and crosstalk noise at a trade‐off marginal increase in power dissipation. Conventionally, Power Delay Product (PDP) criterion is used to insert repeaters into long interconnects. A new criterion, the Power‐Delay‐Crosstalk‐Product (PDCP), is introduced as an efficient condition, to insert repeaters into long coupled interconnect. Various criteria, such as minimum delay, minimum PDP and minimum PDCP, are applied for achieving optimum repeater insertion.The performance of PDCP criterion is compared with PDP criterion in terms of optimum number of repeaters, power dissipation, propagation delay and crosstalk for a wide range of coupling combinations. It is observed that instead of PDP criterion, PDCP criterion is best suited for the determination of optimum number of repeaters for overall minimization of delay, power and crosstalk. Copyright © 2010 John Wiley & Sons, Ltd.
A novel current conveyor‐based Schmitt trigger and its application as a relaxation oscillator
Authors: Srinivasulu Avireni 
Published: April 2010

AbstractThe current paper presents a novel Schmitt trigger using two second‐generation current conveyors and four resistors and its application as a relaxation oscillator. The performance of the proposed circuit is examined using Cadence and the model parameters of a 0.6µm CMOS process. The obtained results demonstrate excellent agreement with the theoretical values. The measured results based on commercially available current feedback operational amplifiers (AD 844 AN) are included and the non‐idealities are also examined. The topology reports low sensitivities and has features suitable for VLSI implementation. Copyright © 2010 John Wiley & Sons, Ltd.