bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qualitative Insights into Organizational Value Creation: Decoding Characteristics of Metaverse Platforms
Authors: Tingelhoff Fabian , Schultheiss Raphael , Schöbel Sofia Marlena , Leimeister Jan Marco 
Published: May 2024

AbstractThe significance of metaverse platforms is growing in both research and practical applications. To utilize the chances and opportunities metaverse platforms offer, research and practice must understand how these platforms create value, which has not been adequately explored. Our research explores the characteristics of metaverse platforms that facilitate value creation for organizations in both B2B and B2C sectors. Employing a qualitative inductive approach, we conducted 15 interviews with decision-makers from international corporations active in the metaverse. We identified 26 metaverse platform characteristics, which we categorized into six dimensions based on the DeLone and McLean Information Systems success model. Subsequently, we provide examples to illustrate the application of these identified characteristics within metaverse platforms. This study contributes to the academic discourse by uncovering the characteristics that shape the competitive landscape of emerging metaverse platforms. Leveraging these characteristics may offer metaverse providers a competitive edge in attracting complementary organizations to their platforms.
Virtual Reality for Cardiopulmonary Resuscitation Healthcare Professionals Training: A Systematic Review
Authors: Trevi Roberto , Chiappinotto Stefania , Palese Alvisa , Galazzi Alessandro 
Published: May 2024

Abstract

Introduction
Virtual reality (VR) is becoming increasingly popular to train health-care professionals (HCPs) to acquire and/or maintain cardiopulmonary resuscitation (CPR) basic or advanced skills.

Aim
To understand whether VR in CPR training or retraining courses can have benefits for patients (neonatal, pediatric, and adult), HCPs and health-care organizations as compared to traditional CPR training.

Methods
A systematic review (PROSPERO: CRD42023431768) following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. In June 2023, the PubMed, Cochrane Library, Scopus and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were searched and included studies evaluated in their methodological quality with Joanna Briggs Institute checklists. Data were narratively summarized.

Results
Fifteen studies published between 2013 and 2023 with overall fair quality were included. No studies investigated patients’ outcomes. At the HCP level, the virtual learning environment was perceived to be engaging, realistic and facilitated the memorization of the procedures; however, limited decision-making, team building, psychological pressure and frenetic environment were underlined as disadvantages. Moreover, a general improvement in performance was reported in the use of the defibrillator and carrying out the chest compressions. At the organizational level, one study performed a cost/benefit evaluation in favor of VR as compared to traditional CPR training.

Conclusions
The use of VR for CPR training and retraining is in an early stage of development. Some benefits at the HCP level are promising. However, more research is needed with standardized approaches to ensure a progressive accumulation of the evidence and inform decisions regarding the best training methodology in this field.
Actinide isotope analysis and trace element composition of bones of prehistoric animals and humans by inductively coupled plasma mass spectrometry (ICP-MS)
Authors: Nesmiyan I. , Ragazzon-Smith A. , Saidullaev B. D. , Vasidov A. , Strashnov I. 
Published: May 2024

AbstractInductively coupled plasma mass spectrometry (ICP-MS) has been used for analysis of the bones of archanthropus, ancient bear, southern mammoths, dinosaurs, as well as soils collected in various parts of Uzbekistan. The concentrations of 64 elements have been detected including thorium and uranium for which isotope compositions were also analysed. The comparison of the ICP-MS data with the results we obtained earlier for some bones using instrumental neutron activation analysis (INAA) is presented. The concentrations of 234, 235, 238U are up to two orders of magnitude elevated compared to the soils (e.g.238U in south mammoth bone—130.1 mg/kg, and that of soil is only 1.6 mg/kg). The levels of 236U, and 239, 240, 242, 244Pu isotopes (possible neutron capture products of 235U and 238U) correspond to a count rate of blank samples. In addition, the isotope analysis confirms the uranium in the bones and surrounding soils is natural (the average determined for all samples uranium ratios 235U/238U = 0.0071 ± 0.0003 (2-sigma errors). The concentration of 230Th (which is the part of 234U and 238U decay chain) is also elevated in the bones compared to the surrounding soils, however, the concentrations of stable 232Th largely correspond to those of the soil. The excess uranium detected in bones is most probably due to the preferential accumulation from soil, and not to the paleo diet.
Properties of biopolymer blends based on Rugulopteryx okamurae and hydrophobic polycaprolactone (PCL) and hydrophilic acylated soy protein isolated (SPIa)
Authors: Santana Ismael , Felix Manuel , Bengoechea Carlos 
Published: May 2024

AbstractThe present study explored the utilization of Rugulopteryx okamurae (RO), an invasive brown seaweed, as a renewable raw material for plastic materials based on biopolymer blends. The goal of this study was to improve the previously observed poor mechanical properties of materials based on single biopolymer RO. To enhance these properties, two polymers with distinct hydrophobicities were incorporated into the formulation of different blends: hydrophobic polycaprolactone (PCL) and hydrophilic acylated soy protein isolate (SPIa). SPIa was derived from soy protein through a chemical modification process, introducing hydrophilic carboxyl groups. The addition of PCL significantly strengthened the blend, increasing the storage modulus (E′1 Hz) from ~ 110 to ~ 250 MPa. Conversely, SPIa incorporation resulted in softening, with E′ values around 40 MPa. Both additives enhanced deformability proportionally to their concentrations, with SPIa exhibiting notably higher deformability, reaching a maximum deformation of ~ 23% for a RO/SPIa ratio of 25/75. In summary, the study demonstrates the feasibility of producing environmentally friendly blend materials based on RO, tailored for specific applications by incorporating suitable additives into the formulation. Therefore, PCL is recommended for applications susceptible to moisture effects, such as packaging, while SPIa is suggested for highly absorbent applications such as personal care or horticulture.
Effects of percutaneous cryoablation for renal tumor on overall and split renal function
Authors: Yamagami Takuji , Yoshimatsu Rika , Nitta Noriko , Miyatake Kana , Iwasa Hitomi , Shibata Junki , Osaki Marina , Maeda Hitomi , Noda Yoshihiro , Yamanishi Tomoaki , Matsumoto Tomohiro , Yamamoto Shinkuro , Karashima Takashi , Inoue Keiji 
Published: May 2024

Abstract
Purpose
To evaluate retrospectively the influence of percutaneous cryoablation for small renal tumors on total and affected kidney function and risk factors associated with worsening function of the affected kidney.

Materials and methods
Between April 2016 and March 2022, 27 patients who underwent cryoablation for small renal tumors at our institution participated in this study, which investigated time-dependent changes in postoperative renal function. We evaluated estimated glomerular filtration rates (eGFRs) and split renal function revealed by scintigraphy using 99 m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before cryoablation and at 1 week, 1 month, and 6 months after cryoablation. Numerous variables were analyzed to assess risk factors for worsening renal function.

Results
Baseline eGFR (mean ± standard deviation) was 56.5 ± 23.7 mL/min/1.73 m2 (mean ± SD; range, 20.5–112.5). Mean eGFRs at 1 week, 1 month, and 6 months after cryoablation were 57.4 ± 24.5 (19.1–114.9), 57.1 ± 25.1 (21.5–114.9), and 53.8 ± 23.9 mL/min/1.73 m2 (20.0–107.5), respectively. Changes were statistically insignificant (p = 1.0000, = 0.6749, and = 0.0761, respectively). Regarding split renal function, mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 49.7% ± 6.0% (38.8–63.3%); these rates at 1 week, 1 month, and 6 months after cryoablation were 43.7% ± 8.8 (29.1–70.6%), 46.2% ± 7.7% (32.6–70.3%), and 46.0% ± 8.5% (32.5–67.6%), respectively. Differences from baseline were significant for all periods (p < 0001, < 0001, = 0.0001, respectively). Serum C reactive protein and lactate dehydrogenase at 1 day following cryoablation, tumor’s nearness to the collecting system or sinus, and volume of ablated normal renal parenchyma were significantly correlated with decreased contributions of the affected kidney by > 10% after cryoablation.

Conclusion
Unlike total renal function, affected kidney function could worsen after cryoablation.
In vitro bioactivity of biodegradable films based on chitosan/quince seed mucilage reinforced with ZnO-nanoparticle
Authors: Emir Coban Ozlem , Akat Zelal , Karatepe Pınar , Incili Gökhan Kürşad 
Published: May 2024

AbstractIn this study, biodegradable active films were designed by adding ZnO-NPs to the quince seed mucilage/chitosan matrix. The films were investigated for characterization and in vitro bioactivity. According to the results, a significant decrease in moisture content, water holding capacity and light (L*) occurred with the addition of ZnO-NP. (p < 0.05). FT-IR spectra showed the interaction between ZnO-NPs and N-H quince seed mucilage and chitosan groups. Nanocomposite films containing ZnO-NP showed improved thermal stability. The developed bionanocomposite films were easily buried in soil and subjected to degradation. The minimum degradation of the film in soil after 20 days was 62.02%. The maximum cell viability (%) of C/ZnO-NP and C/QSM/ZnO-NP films were determined as 86.81% and 91.22%, respectively, and the films were found to be non-toxic. Moreover, while the quince seed mucilage film did not show antibacterial performance, chitosan and ZnO NPs showed antibacterial effects against the tested bacteria Listeria monocytogenes (ATCC 7644) and Escherichia coli O157:H7 (ATCC 35,150). In this context, the design bionanocomposite films can be used as an active food packaging material for food preservation by controlling food-borne pathogens. In addition, the developed films do not pose a threat to the environment and therefore have great potential for the sustainable food packaging industry.
Phytochemical contents and bioactivity of four endemic Salvia seeds from Turkey: a comparative study to chia seed
Authors: Karadeniz-Pekgöz Asuman , Turgut Aslıhan Cesur , Çinbilgel İlker , Yavuz Orhan 
Published: May 2024

AbstractRecently, the importance of medicinal plants such as Salvia species has been increasing both in medicine and in industrial branches, which includes food, feed, and cosmetic raw materials. On the other hand, chia seed is a functional food that has recently increased industrial importance due to its superior nutritional value, phytochemical components, and therapeutic effects. In our study, the antioxidant activity of methanol extracts from the seeds of endemic Salvia cadmica Boiss var. cadmica, and Salvia caespitosa Montbret & Aucher ex Benth., Salvia pisidica Boiss. & Heldr. ex Benth., and Salvia potentillifolia Boiss. & Heldr. ex Benth. collected from Burdur-Antalya/Turkey were determined via 1,1-diphenyl,2-picryl hydrazyl radical scavenging activity, cupric (II) reducing antioxidant capacity, b-carotene/linoleic acid bleaching and total phenolic, and total flavonoid content tests and compared with that of chia seed. Antimicrobial activity was determined according to minimum inhibitory concentration values, on S. aureus, E. coli, S. enterica, L. monocytogenes, C. albicans strains, but it was found negligible. Phenolic and fatty acid contents of the seed extracts were also determined by HPLC and GC–MS, respectively. S. pisidica and S. potentillifolia were found to be highly active. The major fatty acid composition of the chia seed was linolenic acid, linoleic acid, oleic acid, palmitic acid, and stearic acid while the others were linoleic, oleic, palmitic, and stearic acids. Despite fatty acid ratios of chia seed being more favorable; 1,1-diphenyl,2-picryl hydrazyl radical scavenging activity, cupric (II) reducing antioxidant capacity, total phenolic content, and antimicrobial activity of S. pisidica seed extracts and total flavonoid content and inhibition of β-carotene bleaching of S. potentillifolia seed extracts was higher than that of chia seed. These findings suggest seed extracts of these Salvia species are richer in phytochemicals and they are more active as antioxidants when compared to chia seed.
An Anticipatory Approach to Ethico-Legal Implications of Future Neurotechnology
Authors: Rainey Stephen 
Published: May 2024

AbstractThis paper provides a justificatory rationale for recommending the inclusion of imagined future use cases in neurotechnology development processes, specifically for legal and policy ends. Including detailed imaginative engagement with future applications of neurotechnology can serve to connect ethical, legal, and policy issues potentially arising from the translation of brain stimulation research to the public consumer domain. Futurist scholars have for some time recommended approaches that merge creative arts with scientific development in order to theorise possible futures toward which current trends in technology development might be steered. Taking a creative, imaginative approach like this in the neurotechnology context can help move development processes beyond considerations of device functioning, safety, and compliance with existing regulation, and into an active engagement with potential future dynamics brought about by the emergence of the neurotechnology itself. Imagined scenarios can engage with potential consumer uses of devices that might come to challenge legal or policy contexts. An anticipatory, creative approach can imagine what such uses might consist in, and what they might imply. Justifying this approach also prompts a co-responsibility perspective for policymaking in technology contexts. Overall, this furnishes a mode of neurotechnology’s emergence that can avoid crises of confidence in terms of ethico-legal issues, and promote policy responses balanced between knowledge, values, protected innovation potential, and regulatory safeguards.
Between Technological Utopia and Dystopia: Online Expression of Compulsory Use of Surveillance Technology
Authors: Ng Yu-Leung , Lin Zhihuai 
Published: May 2024

AbstractThis study investigated people’s ethical concerns of surveillance technology. By adopting the spectrum of technological utopian and dystopian narratives, how people perceive a society constructed through the compulsory use of surveillance technology was explored. This study empirically examined the anonymous online expression of attitudes toward the society-wide, compulsory adoption of a contact tracing app that affected almost every aspect of all people’s everyday lives at a societal level. By applying the structural topic modeling approach to analyze comments on four Hong Kong anonymous discussion forums, topics concerning the technological utopian, dystopian, and pragmatic views on the surveillance app were discovered. The findings showed that people with a technological utopian view on this app believed that the implementation of compulsory app use can facilitate social good and maintain social order. In contrast, individuals who had a technological dystopian view expressed privacy concerns and distrust of this surveillance technology. Techno-pragmatists took a balanced approach and evaluated its implementation practically.
Insight into the Relationship Between Motor and Cognitive Symptoms in Essential Tremor
Authors: Paparella Giulia , Angelini Luca , Margiotta Roberta , Passaretti Massimiliano , Birreci Daniele , Costa Davide , Cannavacciuolo Antonio , De Riggi Martina , Alunni Fegatelli Danilo , Bologna Matteo 
Published: May 2024

AbstractEssential tremor (ET) is a heterogeneous disorder characterized by bilateral upper limbs action tremor and, possibly, neurological signs of uncertain significance, including voluntary movement abnormalities and cognitive disturbances, i.e., the so-called ‘soft’ signs configuring the ET-plus definition. While motor and cognitive disturbances often coexist in ET, their interrelationship remains largely unexplored. Here we aim to further investigate the relationship between motor symptoms, objectively assessed through kinematic analysis, and cognitive dysfunctions in ET. Seventy ET patients underwent clinical examination, as well as kinematic recordings of tremor and finger tapping and a thorough cognitive assessment. We then tested clinic-demographic and kinematic differences between patients with and without cognitive abnormalities, i.e., with mild cognitive impairment (MCI). Correlation analysis served to explore potential associations between kinematic and cognitive data. Forty-three ET patients (61.42%) had MCI. ET-MCI patients exhibited reduced movement velocity during finger tapping compared to those with normal cognition (p < 0.001). Lower movement velocity during finger tapping was associated with poorer cognitive performance. Namely, we observed a correlation between movement velocity and performance on the Babcock Story Immediate and Delayed Recall Test (r = 0.52 and r = 0.45, both p < 0.001), as well as the interference memory task at 10 and 30 s (r = 0.3, p = 0.008 and r = 0.2, p = 0.03). In this study, we have provided data for a better pathophysiological interpretation of motor and cognitive signs in ET, including the role played by the cerebellum or extra-cerebellar areas, which possibly underpin both signs.
Targeting neutrophil elastase is a promising direction for future cancer treatment
Authors: Jia Wangqiang , Mao Yudong , Luo Qianwen , Wu Jiang , Guan Quanlin 
Published: May 2024

AbstractNeutrophil elastase (NE) is a proteolytic enzyme released extracellular during the formation of neutrophil extracellular traps (NETs) through degranulation. In addition to participating in the body's inflammatory response, NE also plays an important role in cancer. It can promote tumor proliferation, migration, and invasion, induce epithelial-mesenchymal transition (EMT), and change the tumor microenvironment (TME) to promote tumor progression. Concurrently, NE promotes systemic treatment resistance by inducing EMT. However, it can also selectively kill cancer cells and attenuate tumor development. Sivelestat is a specific NE inhibitor that can be used in the perioperative period of esophageal cancer patients to reduce the incidence of postoperative complications after esophagectomy. In addition, the combination of sivelestat and trastuzumab can enhance the efficacy of human epidermal growth factor receptor 2(HER 2) positive breast cancer patients. Meanwhile, targeting the human antibody domains and fragments of NE is also a new way to treat cancer and inflammation-related diseases. This review provides valuable insights into the role of NE in cancer treatment. Additionally, we discuss the challenges associated with the clinical application of sivelestat. By shedding light on the promising potential of NE, this review contributes to the advancement of cancer treatment strategies.
Toward Reducing Casting Defects via 3D Risers via 3D Sand-Printing: A Simulation Study
Authors: Shuvo Md Moinuddin , King Philip , Voigt Robert , Manogharan Guha 
Published: May 2024

AbstractThe 3D sand printing (3DSP) process is a binder jetting class of additive manufacturing process that can incorporate complex 3D mold designs and consolidate cores with intricate features that were previously inaccessible. Prior studies in 3DSP mold design have been shown to improve pouring and filling conditions for sand casting. However, the opportunity to improve casting quality by exploring 3D riser designs during the solidification stage has not yet been explored. In this research, three novel 3D riser geometries—ellipsoid, spherical, and a fusion riser (combination of cylindrical and ellipsoid riser) were investigated. The results were compared to the benchmark cylindrical risers to assess casting performance (e.g., reduction in shrinkage porosity, increase in solidification time). Computational solidification simulations have been presented to evaluate the characteristics of the novel risers for three different metal alloys- nickel aluminum bronze (NAB), low-carbon steel A216 (WCB), and aluminum alloy (A319) alloy. From the results of this research, spherical risers were found to provide 45% yield improvement of for the three alloys studied. In addition, the riser neck diameter using a spherical riser experienced up to 77% reduction when compared to the recommended dimensions from previous literature. Finally, one of the spherical riser designs provided 18% improvement in terms of riser-pipe safety height over the benchmark design. Findings from this research will help metalcasting industries to optimize their riser designs for complex casting geometries by implementing 3D riser geometries (via 3DSP) into traditional mold making for yield improvement and defect-free castings.
Crossing the distance: University student newcomer socialization in online semesters—a case study
Authors: Berger Sonja , Stadler Matthias , Sailer Michael , Eberle Julia , Cooper-Thomas Helena D. , Stegmann Karsten 
Published: May 2024

AbstractDuring the COVID-19 pandemic, emergency online learning impeded the pursuit of in-person activities that usually foster successful socialization in higher education. To investigate the effects of online learning on socialization, we asked two exploratory research questions: (1) How and to what extent does the level of socialization change during the first online semester? and (2) To what extent does level of change predict course dropout and academic performance? In our case study, using a sample of new students at a large German university, we ran an autoregressive three-factorial model of socialization (role, relationships, organization) with three measurements taken during the new students’ first semester, which was the second semester in which emergency online learning took place. Our results show that the relationships component of socialization did not increase over the semester, while the role and organization components increased. Furthermore, our results support a negative effect of the organization component of socialization on course dropout and a positive effect of the relationship component of socialization on academic performance.