bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE IMPACT OF ANALYTICAL SUPPORT AND PREFERENCE DETERMINATION ON CONSISTENCY IN E-NEGOTIATIONS — A NEW METHOD AND PRELIMINARY RESULTS
Authors: FILZMOSER MICHAEL , RIOS JESUS , STRECKER STEFAN , VETSCHERA RUDOLF 
Published: August 2010

This paper explores whether the decisions made by a negotiator during negotiations are consistent with her preferences. By considering the entire set of offers exchanged during a negotiation, the measures of consistency developed in this paper provide a compact representation of important behavioral characteristics throughout the negotiation process. The consistency measures developed in this paper are validated with data from an experimental study in which the impact of two factors on negotiation processes is studied: the availability of analytical support and imposed vs. elicited preferences. We find that negotiators behave more consistently when preferences are assigned to them by the experimenters than when their preferences are elicited. On the other hand, an impact of analytical support is only found when preferences are elicited. These results shed light on both the design of negotiation experiments and the development of negotiation support systems.
泉州城郊“巴厘华人村”：
Authors: 陈志明  , 丁毓玲  
Published: August 2010

在1960年代，福建泉州作为中国侨乡，被安排创建了三个华侨农场，以接收这一时期从东南亚，尤其是印尼、越南的难侨。绝大多数归侨安置的农场所在地不是他们祖先的家乡，而且由于气候的不同，尤其是语言、饮食等等的习惯不同于农场周围的本地人，他们一下子迷失在回“家乡”的想象中。经过短暂的挣扎和调整，他们面对现实，成为中国政府编制内的农民。除了和当地的农民一样，按照当时的集体制农业生产的计工分方式农作外，他们的生活圈子相对独立。华侨农场和他们的生活区就是他们的“居住地家乡”，被当地人称为泉州的“小南洋”，有东南亚特色的饮食，也有操印尼国语、爪哇语、巴厘语的人们。本世纪初，由于政府体制改革，归侨心中的“组织” — 农场解体了，华侨农场从此退出了历史舞台，归侨们再次迷失在“居住地家乡”中。 本文以泉州郊区双阳华侨农场的南山 — 安置印尼巴厘岛归侨的社区为例，讨论华侨农场归侨的文化适应、家乡怀思，以及华侨农场改制后归侨的生存状态和文化保持，同时还讨论归侨的“家乡”概念。
A Combination of Serum Markers for the Early Detection of Colorectal Cancer
Authors: Wild Norbert , Andres Herbert , Rollinger Wolfgang , Krause Friedemann , Dilba Peter , Tacke Michael , Karl Johann 
Published: August 2010

AbstractPurpose: Fecal occult blood testing is recommended as first-line screening to detect colorectal cancer (CRC). We evaluated markers and marker combinations in serum as an alternative to improve the detection of CRC.Experimental Design: Using penalized logistic regression, 6 markers were selected for evaluation in 1,027 samples (301 CRC patients, 143 patients with adenoma, 266 controls, 141 disease controls, and 176 patients with other cancer). The diagnostic performance of each marker and of marker combinations was assessed.Results: To detect CRC from serum samples, we tested 22 biomarkers. Six markers were selected for a marker combination, including the known tumor markers CEA (carcinoembryonic antigen) and CYFRA 21-1 as well as novel markers or markers that are less routinely used for the detection of CRC: ferritin, osteopontin (OPN), anti-p53, and seprase. CEA showed the best sensitivity at 95% specificity with 43.9%, followed by seprase (42.4%), CYFRA 21-1 (35.5%), OPN (30.2%), ferritin (23.9%), and anti-p53 (20.0%). A combination of these markers gave 69.6% sensitivity at 95% specificity and 58.7% at 98% specificity. Focusing on International Union against Cancer (UICC) stages 0–III reduced the sensitivity slightly to 68.0% and 53.3%, respectively. In a subcollective, with matched stool samples (75 CRC cases and 234 controls), the sensitivity of the marker combination was comparable with fecal immunochemical testing (FIT) with 82.4% and 68.9% versus 81.8% and 72.7% at 95% and 98% specificity, respectively.Conclusions: The performance of the serum marker combination is comparable with FIT. This provides a novel tool for CRC screening to trigger a follow-up colonoscopy for a final diagnosis. Clin Cancer Res; 16(24); 6111–21. ©2010 AACR.
Application of the Seattle Heart Failure Model in Ambulatory Patients Presented to an Advanced Heart Failure Therapeutics Committee
Authors: Gorodeski Eiran Z. , Chu Eric C. , Chow Chen H. , Levy Wayne C. , Hsich Eileen , Starling Randall C. 
Published: August 2010

Background—
We sought to assess the predictive value of the Seattle Heart Failure Model (SHFM) when applied to ambulatory patients with advanced heart failure (HF) presented to an advanced HF therapeutics committee at a tertiary care US institution.

Methods and Results—
We evaluated model discrimination and calibration in 215 consecutive ambulatory patients who were presented to the Cleveland Clinic advanced HF therapeutics committee between 2004 to 2007 for evaluation for advanced options including transplantation and ventricular assist device (VAD). Analyses were stratified by committee decision (not listed versus listed United Network of Organ Sharing [UNOS] Status 2). Eighty-five percent had 1 or no missing SHFM variables. The primary outcome was a composite of all-cause mortality, VAD, or urgent (UNOS Status 1) transplantation. During a median follow-up of 24 months, 68 died, 18 received VAD support, and 81 underwent heart transplantation. Discrimination was modest both for those not listed (c-index, 0.683 at 1 year and 0.648 at 2 years), and for those listed UNOS status 2 (c-index, 0.629 at 1 year and 0.628 at 2 years). Calibration was acceptable among those patients not listed for heart transplantation but with substantial underestimation of risk (ie, overestimation of survival free of VAD or urgent transplantation) among UNOS status 2 patients.

Conclusions—
In ambulatory patients presented to an advanced HF therapeutics committee for evaluation for heart transplantation, the SHFM offers modest discrimination of risk for the primary composite outcome of mortality, VAD, or urgent transplantation, with underestimation of risk in those patients listed for nonurgent transplantation. Interpretation of risk prediction by the SHFM in this patient population must be done with caution.
Joining the Club: A Suggestion about Genre in Early Jewish Texts
Authors: Wright Benjamin G. III 
Published: August 2010

AbstractBiblical studies has traditionally worked with a classificatory or definitional approach to genre. Recent scholarship in genre studies, however, has pointed out the shortcomings of a classificatory system. Among the different theories about genre that are current in genre studies, prototype theory, derived from advances in cognitive science, offers the possibility for thinking differently about genre as a classificatory tool and about what questions we want considerations of genre to answer. Rather than listing necessary features, prototype theory focuses on the way that humans categorize through the use of prototypical exemplars that reflect an idealized cognitive model of a category. Within this approach, genres have indeterminate boundaries and can be extended to include marginal or atypical examples. This paper takes up the categories of apocalyptic and wisdom as examples of how prototype theory can be used to describe a genre, to provide a more effective way to accommodate what are usually thought of as problematic cases, and to think about the generic relations of texts to one another.
Genre Theory, Rewritten Bible and Pesher
Authors: Brooke George J. 
Published: August 2010

AbstractThis article considers how the wide range of compositions from the Second Temple period that represent or depend implicitly or explicitly on some form of authoritative Jewish scripture should be suitably described and categorized. Three broad sets of issues are addressed. The first concerns how the “authority” of texts or textual traditions within particular groups of texts should be articulated suitably, particularly in relation to the respective roles for form, content and function in such articulations. The second concerns the role that should be played by reflections on the hierarchy of genres, generic instability, and evolutionary models of genre construction in how it is appropriate to distinguish earlier from later, or authoritative from dependent, primary from secondary compositions. The third concerns what labels might suitably be imposed on this broad range of literature, a breadth of literary compositions that seldom makes plain how it understands itself. The questions are addressed by the open-ended definition of the corpus to be studied, by consideration of the problems surrounding the criteria for generic definition, by reviewing the perspectives derived from thinking about the evolution of genres, and by giving some place to the need for cross-cultural analogies. A concluding section asks diachronic and synchronic questions about anthologies of authoritative texts and their interpretations.
The Epistle of Enoch: Genre and Authorial Presentation
Authors: Stuckenbruck Loren T. 
Published: August 2010

AbstractTo the extent that a writing openly presents itself as the result of authorial activity, discussions of genre cannot dispense with the question of how, formally, communication occurs. Taking the Epistle of Enoch and Apocalypse of Weeks in 1 Enochas the points of departure, the present essay attempts to show that a discussion of what a document declares about its own writtenness opens up a way of understanding it in comparison to other documents that do the same along analogous lines, whether sapiential or apocalyptic.
Impact of Cloud-Nucleating Aerosols in Cloud-Resolving Model Simulations of Warm-Rain Precipitation in the East China Sea
Authors: Saleeby Stephen M. , Berg Wesley , van den Heever Susan , L’Ecuyer Tristan 
Published: August 2010

Abstract
Cloud-nucleating aerosols emitted from mainland China have the potential to influence cloud and precipitation systems that propagate through the region of the East China Sea. Both simulations from the Spectral Radiation-Transport Model for Aerosol Species (SPRINTARS) and observations from the Moderate Resolution Imaging Spectroradiometer (MODIS) reveal plumes of pollution that are transported into the East China Sea via frontal passage or other offshore flow. Under such conditions, satellite-derived precipitation estimates from the Tropical Rainfall Measuring Mission (TRMM) Microwave Imager (TMI) and Precipitation Radar (PR) frequently produce discrepancies in rainfall estimates that are hypothesized to be a result of aerosol modification of cloud and raindrop size distributions. Cloud-resolving model simulations were used to explore the impact of aerosol loading on three identified frontal-passage events in which the TMI and PR precipitation estimates displayed large discrepancies. Each of these events was characterized by convective and stratiform elements in association with a frontal passage. Area-averaged time series for each event reveal similar monotonic cloud and rain microphysical responses to aerosol loading. The ratio in the vertical distribution of cloud water to rainwater increased. Cloud droplet concentration increased and the mean diameters decreased, thereby reducing droplet autoconversion and collision–coalescence growth. As a result, raindrop concentration decreased, while the drop mean diameter increased; furthermore, average rainwater path magnitude and area fraction both decreased. The average precipitation rate fields reveal a complex modification of the timing and spatial coverage of rainfall. This suggests that the warm-rain microphysical response to aerosols, in addition to the precipitation life cycle, microphysical feedbacks, and evaporative effects, play an important role in determining surface rainfall.
Quantifying Differences in Circulation Patterns Based on Probabilistic Models: IPCC AR4 Multimodel Comparison for the North Atlantic*
Authors: Rust Henning W. , Vrac Mathieu , Lengaigne Matthieu , Sultan Benjamin 
Published: August 2010

Abstract
The comparison of circulation patterns (CPs) obtained from reanalysis data to those from general circulation model (GCM) simulations is a frequent task for model validation, downscaling of GCM simulations, or other climate change–related studies. Here, the authors suggest a set of measures to quantify the differences between CPs. A combination of clustering using Gaussian mixture models with a set of related difference measures allows for taking cluster size and shape information into account and thus provides more information than the Euclidean distances between cluster centroids. The characteristics of the various distance measures are illustrated with a simple simulated example. Subsequently, a five-component Gaussian mixture to define circulation patterns for the North Atlantic region from reanalysis data and GCM simulations is used. CPs are obtained independently for the NCEP–NCAR reanalysis and the 40-yr European Centre for Medium-Range Weather Forecasts (ECMWF) Re-Analysis (ERA-40), as well as for twentieth-century simulations from 14 GCMs of the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4) database. After discussing the difference of CPs based on spherical and nonspherical clusters for the reanalysis datasets, the authors give a detailed evaluation of the cluster configuration for two GCMs relative to NCEP–NCAR. Finally, as an illustration, the capability of reproducing the NCEP–NCAR probability density function (pdf) defining the Greenland anticyclone CP is evaluated for all 14 GCMs, considering that the size and shape of the underlying pdfs complement the commonly used Euclidean distance of CPs’ mean values.
Two Limits of Initial-Value Decadal Predictability in a CGCM
Authors: Branstator Grant , Teng Haiyan 
Published: August 2010

Abstract
When the climate system experiences time-dependent external forcing (e.g., from increases in greenhouse gas and aerosol concentrations), there are two inherent limits on the gain in skill of decadal climate predictions that can be attained from initializing with the observed ocean state. One is the classical initial-value predictability limit that is a consequence of the system being chaotic, and the other corresponds to the forecast range at which information from the initial conditions is overcome by the forced response. These limits are not caused by model errors; they correspond to limits on the range of useful forecasts that would exist even if nature behaved exactly as the model behaves. In this paper these two limits are quantified for the Community Climate System Model, version 3 (CCSM3), with several 40-member climate change scenario experiments. Predictability of the upper-300-m ocean temperature, on basin and global scales, is estimated by relative entropy from information theory. Despite some regional variations, overall, information from the ocean initial conditions exceeds that from the forced response for about 7 yr. After about a decade the classical initial-value predictability limit is reached, at which point the initial conditions have no remaining impact. Initial-value predictability receives a larger contribution from ensemble mean signals than from the distribution about the mean. Based on the two quantified limits, the conclusion is drawn that, to the extent that predictive skill relies solely on upper-ocean heat content, in CCSM3 decadal prediction beyond a range of about 10 yr is a boundary condition problem rather than an initial-value problem. Factors that the results of this study are sensitive and insensitive to are also discussed.
Understanding the Daily Cycle of Evapotranspiration: A Method to Quantify the Influence of Forcings and Feedbacks
Authors: van Heerwaarden Chiel C. , Vilà-Guerau de Arellano Jordi , Gounou Amanda , Guichard Françoise , Couvreux Fleur 
Published: August 2010

Abstract
A method to analyze the daily cycle of evapotranspiration over land is presented. It quantifies the influence of external forcings, such as radiation and advection, and of internal feedbacks induced by boundary layer, surface layer, and land surface processes on evapotranspiration. It consists of a budget equation for evapotranspiration that is derived by combining a time derivative of the Penman–Monteith equation with a mixed-layer model for the convective boundary layer. Measurements and model results for days at two contrasting locations are analyzed using the method: midlatitudes (Cabauw, Netherlands) and semiarid (Niamey, Niger). The analysis shows that the time evolution of evapotranspiration is a complex interplay of forcings and feedbacks. Although evapotranspiration is initiated by radiation, it is significantly regulated by the atmospheric boundary layer and the land surface throughout the day. In both cases boundary layer feedbacks enhance the evapotranspiration up to 20 W m−2 h−1. However, in the case of Niamey this is offset by the land surface feedbacks since the soil drying reaches −30 W m−2 h−1. Remarkably, surface layer feedbacks are of negligible importance in a fully coupled system. Analysis of the boundary layer feedbacks hints at the existence of two regimes in this feedback depending on atmospheric temperature, with a gradual transition region in between the two. In the low-temperature regime specific humidity variations induced by evapotranspiration and dry-air entrainment have a strong impact on the evapotranspiration. In the high-temperature regime the impact of humidity variations is less pronounced and the effects of boundary layer feedbacks are mostly determined by temperature variations.
Regional Extreme Monthly Precipitation Simulated by NARCCAP RCMs
Authors: Gutowski William J. , Arritt Raymond W. , Kawazoe Sho , Flory David M. , Takle Eugene S. , Biner Sébastien , Caya Daniel , Jones Richard G. , Laprise René , Leung L. Ruby , Mearns Linda O. , Moufouma-Okia Wilfran , Nunes Ana M. B. , Qian Yun , Roads John O. , Sloan Lisa C. , Snyder Mark A. 
Published: August 2010

Abstract
This paper analyzes the ability of the North American Regional Climate Change Assessment Program (NARCCAP) ensemble of regional climate models to simulate extreme monthly precipitation and its supporting circulation for regions of North America, comparing 18 years of simulations driven by the National Centers for Environmental Prediction (NCEP)–Department of Energy (DOE) reanalysis with observations. The analysis focuses on the wettest 10% of months during the cold half of the year (October–March), when it is assumed that resolved synoptic circulation governs precipitation. For a coastal California region where the precipitation is largely topographic, the models individually and collectively replicate well the monthly frequency of extremes, the amount of extreme precipitation, and the 500-hPa circulation anomaly associated with the extremes. The models also replicate very well the statistics of the interannual variability of occurrences of extremes. For an interior region containing the upper Mississippi River basin, where precipitation is more dependent on internally generated storms, the models agree with observations in both monthly frequency and magnitude, although not as closely as for coastal California. In addition, simulated circulation anomalies for extreme months are similar to those in observations. Each region has important seasonally varying precipitation processes that govern the occurrence of extremes in the observations, and the models appear to replicate well those variations.
Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features
Authors: Kumar Shaji , Dispenzieri Angela , Katzmann Jerry A. , Larson Dirk R. , Colby Colin L. , Lacy Martha Q. , Hayman Suzanne R. , Buadi Francis K. , Leung Nelson , Zeldenrust Steve R. , Ramirez-Alvarado Marina , Clark Raynell J. , Kyle Robert A. , Rajkumar S. Vincent , Gertz Morie A. 
Published: August 2010

AbstractImmunoglobulin free light chains (FLCs) are the precursors of amyloid fibrils in primary amyloidosis (AL). We studied the relationship between FLC levels and clinical features in 730 patients with newly diagnosed AL. The plasma cell clone was λ in 72% patients, and κ in 28% patients. κ-AL had more GI tract and liver involvement, where as renal involvement was more with λ-AL. While the overall survival (OS) was similar for κ and λ-AL, the median OS for those without an identifiable serum heavy chain was significantly shorter (12.6 vs 29.9 months; P = .02). The OS was shorter among those with a higher dFLC (involved FLC−uninvolved FLC; κ > 29.4 mg/dL or λ > 18.2 mg/dL using median for cutoff); 10.9 vs 37.1 months; P < .001. In multivariate analysis, dFLC was independent of other prognostic factors. The type of light chain impacts the spectrum of organ involvement and the FLC burden correlates with survival in AL.
L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions
Authors: Pfeifer Marco , Schirmer Uwe , Geismann Claudia , Schäfer Heiner , Sebens Susanne , Altevogt Peter 
Published: August 2010

Abstract

Background
The L1 cell adhesion molecule (L1CAM) was originally identified as a neural adhesion molecule involved in axon guidance. In many human epithelial carcinomas L1CAM is overexpressed and thereby augments cell motility, invasion and metastasis formation. L1CAM positive carcinomas are associated with bad prognosis. Recent data point out that L1CAM is regulated in a fashion similar to epithelial-mesenchymal transition (EMT). Previous studies have implied the transcription factors Slug and/or β-catenin in L1CAM transcriptional regulation. However, the regulation of human L1CAM expression at the transcriptional level is not well understood.

Results
To better understand the molecular basis of L1CAM transcriptional regulation, we carried out a detailed characterization of the human L1CAM promoter. We identified two transcription start sites, the first in front of a non-translated exon 0 (promoter 1) and the other next to the first protein-coding exon 1 (promoter 2). Both sites could be verified in endometrial carcinoma (EC) cell lines and appear to be used in a cell-type specific manner. The two identified promoter regions showed activity in luciferase reporter assays. Chromatin-IP analyses confirmed the in silico predicted E-boxes, binding sites for transcription factors Snail and Slug, as well as Lef-1 sites, which are related to β-catenin-mediated transcriptional regulation, in both promoters. Overexpression of β-catenin exclusively augmented activity of promoter 1 whereas Slug enhanced promoter 1 and 2 activity suggesting that both promoters can be active. Overexpression of β-catenin or Slug could upregulate L1CAM expression in a cell-type specific manner.

Conclusions
Our results, for the first time, provide evidence that the L1CAM gene has two functionally active promoter sites that are used in a cell-type specific manner. Slug and β-catenin are involved L1CAM transcriptional regulation. Nevertheless, Slug rather than β-catenin levels are correlated with L1CAM expression in EC cell lines. Our findings suggest that the L1CAM transcriptional regulation is more complex than anticipated and this study provides the basis for a better understanding of L1CAM regulation in non-neuronal/tumor cells.