bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metastatic urothelial carcinoma with signet ring features: Cytomorphologic findings in abdominal paracentesis
Authors: Cimino‐Mathews Ashley , Ali Syed Z. 
Published: May 2010

AbstractSignet ring cells, characterized by large clear cytoplasmic vacuoles eccentrically displacing and indenting the nuclei, seen in cytopathology effusion specimens are most commonly due to metastatic adenocarcinoma of gastric, esophageal, and breast origin. Urothelial carcinoma can display a wide range of differentiation and is an extremely rare cause of metastatic signet ring cells. Here, we report the case of a 75‐year‐old male with high‐grade urothelial carcinoma with signet ring features, who was status‐post chemoradiation and radical cystoprostatectomy. The patient subsequently developed an abdominal mass and ascites. The paracentesis cytology revealed a hypercellular specimen with malignant cells dispersed singly as well as in small fragments displaying pleomorphism, nuclear irregularity, hyperchromasia, and binucleation. Numerous malignant cells displayed well‐formed signet ring morphology, identical to adenocarcinoma. This is the first report of metastatic high‐grade urothelial carcinoma manifesting as signet ring cells in peritoneal fluid. Diagn. Cytopathol. 2011;39:132–134. © 2010 Wiley‐Liss, Inc.
Primary malignant deciduoid peritoneal mesothelioma: A report of the cytohistological and immunohistochemical appearances
Authors: Ustun Huseyin , Astarci Hesna Muzeyyen , Sungu Nuran , Ozdemir Arif , Ekinci Cemil 
Published: May 2010

AbstractMalignant deciduoid mesothelioma (MDM) is a rare variant of epithelioid mesothelioma. This type of tumor might be associated with the asbestos exposure and carries a poor prognosis in general. MDM was first described by Nascimento et al. in 1994 in a peritoneal lesion of a young woman. And its diagnosis is frequently mistaken with florid mesothelial hyperplasia and peritoneal deciduosis. There are 44 MDM cases reported in the literature up today.A 59‐year‐old woman patient referred to our clinic was identified with an abdominal mass. Computed tomography of whole abdomen of the patient showed a mass with the widest transverse dimension of 65 × 60 mm at abdominal bifurcation in the mesenteric region. The patient was diagnosed with MDM after the cytopathological examination of the fine needle aspiration biopsy performed from the mass. Consequently, she received a total mass excision and right hemicolectomy under general anesthesia.The cytomorphological appearance of the ascitic fluid is detailed for the first time by Gillespie et al. and is described only in two manuscripts. In the present study, we aimed to report a case of a 59‐year‐old woman since she was diagnosed with MDM and because her cytological findings were further supported by histomorphological and immunohistochemical evaluations of the operation material obtained from the patient. Diagn. Cytopathol. 2011;39:402–408. © 2010 Wiley‐Liss, Inc.
Environmental policy integration: a state of the art review
Authors: Jordan Andrew , Lenschow Andrea 
Published: May 2010

AbstractThe principle of environmental policy integration (EPI) attracts great scholarly interest as well as widespread political backing. Political support is particularly strong in the European Union, where it enjoys a prominent quasi‐constitutional status. However, the practical fulfilment of EPI appears to lag well behind these aspirations, although the evidence base of this widely held view remains rather fragmented. This article aims to review the ‘state of the art’ in EPI research and practice from the perspective of its conceptual meaning, processes of implementation and outcomes ‘on the ground’. It finds that the political commitment to EPI is indeed widespread, especially in industrialized states, but that deep disagreement surrounds its actual application. In terms of everyday practices, ‘policy integration’ is complex and contingent, and there are few ‘best practices’ that can be easily shared between jurisdictions. Finally, knowledge about policy outcomes is very sparse indeed, and policy‐making systems seem very ill prepared to address this lacuna. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Cyano‐Bridged 2D Bimetallic 4f–3d Arrays with Monolayered Stair‐Like, Brick‐Wall‐Like, or Bilayered Topologies – Rational Syntheses and Crystal Structures
Authors: Chen Wen‐Tong , Wu A‐Qing , Guo Guo‐Cong , Wang Ming‐Sheng , Cai Li‐Zhen , Huang Jin‐Shun 
Published: May 2010

AbstractThree series of fourteen cyano‐bridged 2D LnIII–FeIII or LnIII–CoIII complexes, [Ln(dmso)2(H2O)(μ‐CN)4Fe(CN)2]n [Ln = Gd (1) and Er (2)], [Ln(dmso)2(H2O)3(μ‐CN)3M(CN)3]n [La–Fe (3) and Pr–Co (4)], [Ln(dmf)2(H2O)3(μ‐CN)3M(CN)3]n·nH2O [Nd–Fe (5), Gd–Fe (6), Dy–Fe (7), Er–Fe (8), Nd–Co (9), and Gd–Co (10)], [Ln(dmso)2(H2O)3(μ‐CN)3Co(CN)3]n·nH2O [Ln = Pr (11), Nd (12), and Sm (13)], and [Er(dmf)(H2O)3(μ‐CN)4Co(CN)2]n·nH2O (14) (dmso = dimethyl sulfoxide; dmf = N,N′‐dimethylformamide) were rationally prepared by the ball‐milling method, and their structures were characterized. The crystal structures of 1 and 2 reveal a sevenfold coordination environment of the Ln3+ ions and a 2D stair‐like structure, while those of 3–13 show an eightfold coordination environment of the Ln3+ ions and a 2D monolayered brick‐wall‐like topology and that of 14 exhibits an eightfold coordination environment of the Er3+ ions and a 2D bilayered topology. The relationship between the crystal structures and the controllable synthesis was also discussed.
Actinyl Compounds with Hexavalent Elements (S, Cr, Se, Mo) – Structural Diversity, Nanoscale Chemistry, and Cellular Automata Modeling
Authors: Krivovichev Sergey V. 
Published: May 2010

AbstractActinyl oxysalts with TO4 tetrahedral oxyanions (T = S, Se, Cr, Mo) demonstrate a remarkable structural diversity, owing to the flexibility of the An–O–T linkages, which results in a multitude of topological and geometrical variations. Application of graph representation of structural units allows topological classification of structures and analysis of topological and geometrical isomers. In some organically templated structures, isomerism is controlled by the interplay of hydrophobic/hydrophilic interactions between organic and inorganic substructures. The high flexibility of actinyl oxysalt complexes (in particular, in uranyl selenates) allows strong curvature of inorganic units and formation of curved nanoscale tubules assembled from [1+4+1] complexes. In some particular systems, the self‐assembly process may be modeled using a cellular automata approach.
Non‐Centrosymmetric Ammonium Rare Earth Nitrates (NH4)2Ln(NO3)5·4H2O – Crystal Structure, Crystal Growth and Optical Properties
Authors: Bohatý Ladislav , Fröhlich Roland , Held Peter , Becker Petra 
Published: May 2010

AbstractFor crystals of (NH4)2Ln(NO3)5·4H2O (Ln = La, Ce, Pr, Nd), the piezoelectric and the pyroelectric effect was demonstrated unambiguously. X‐ray structure determination shows that all four compounds are isomorphic, with monoclinic, non‐centrosymmetric space group Cc, and are further isomorphic to the related rubidium compounds Rb2Ln(NO3)5·4H2O. Large single crystals of the colourless compounds (NH4)2La(NO3)5·4H2O and (NH4)2Ce(NO3)5·4H2O were grown. On the basis of determined precise refractive indices and their dispersion in the wavelength region 0.365–1.083 μm, phase‐matching conditions for collinear second harmonic generation were analyzed. In both crystals, type I phase matching can be realized for wavelengths from 0.893 μm (La) or 0.892 μm (Ce) to the near IR, where first absorption bands appear.
Chiral Chalcogen Peptides as Ligands for the Catalytic Enantioselective Aryl Transfer Reaction to Aldehydes
Authors: Schwab Ricardo S. , Soares Letiere C. , Dornelles Luciano , Rodrigues Oscar E. D. , Paixão Márcio W. , Godoi Marcelo , Braga Antonio L. 
Published: May 2010

AbstractA new series of chiral chalcogen peptides were synthesized from inexpensive and commercially available starting materials. The synthesized compounds were tested as catalysts in the enantioselective arylation of aldehydes by using arylboronic acids as the aryl source. The desired diarylmethanols were obtained in excellent yields and with enantioselectivities up to 91 % ee.
Diverse Strategies for the Synthesis of the Indoline Scaffold
Authors: Liu Dianyu , Zhao Guowei , Xiang Lan 
Published: May 2010

AbstractBecause indoline is an important intermediate of angiotensin‐converting enzyme (ACE) inhibitor and the antihypertensive drug “pentopril”, and also because it is a ubiquitous scaffold found in the structures of several naturally bioactive alkaloids such as vinblastine, strychnine, (–)‐physostigmine, ajmaline, and (+)‐aspidospermidine, the synthesis of this “privileged structure” is meaningful in the design of new biologically active medicines. This microreview describes the recent advances in the synthesis of indoline derivatives, including Cu‐ and Pd‐catalyzed reactions, metal‐free approaches (radical reaction), as well as other types of reactions.
Addition/Cycloaddition of Acetylenedicarboxylates to Open‐Chain or Cyclic Amino Carbonyl Compounds
Authors: Guerrini Giacomo , Ponticelli Fabio 
Published: May 2010

AbstractSome new, interesting, and unknown heterocyclic rings and open‐chain molecules have been obtained with ease and under mild conditions by reaction of a wide range of aminocarbonyl compounds with acetylenic esters. The reactivity is highly dependent on the substituents and their positions in the starting material, which can be either cyclic (pyrazolones) or open‐chain compounds.
Online Monitoring of Microwave‐Enhanced Reactions by UV/Vis Spectroscopy
Authors: Heller Eberhard , Klöckner Jessica , Lautenschläger Werner , Holzgrabe Ulrike 
Published: May 2010

AbstractMicrowave‐enhanced reactions are very fast in comparison to thermal reactions. They are often finished within a few minutes. Thus, the determination of the end point often fails, because conventional analytical methods are too slow. We developed a fast method using a UV/Vis sensor, which allows a direct online monitoring of the reaction process. The potency of the method is demonstrated by means of five representative reactions.
Genetic and expression analysis of all non‐synonymous single nucleotide polymorphisms in the human deoxyribonuclease I‐like 1 and 2 genes
Authors: Ueki Misuzu , Fujihara Junko , Takeshita Haruo , Kimura‐Kataoka Kaori , Iida Reiko , Nakajima Tamiko , Kominato Yoshihiko , Yuasa Isao , Yasuda Toshihiro 
Published: May 2010

AbstractMembers of the human DNase I family, DNase I‐like 1 and 2 (DNases 1L1 and 1L2), with physiological role(s) other than those of DNase I, possess three and one non‐synonymous SNPs in the genes, respectively. However, only limited population data are available, and the effect of these SNPs on the catalytic activity of the enzyme remains unknown. Genotyping of all the non‐synonymous SNPs was performed in three ethnic groups including six different populations using the PCR‐RFLP method newly developed. Asian and African groups including Japanese, Koreans, Ghanaians and Ovambos were typed as a single genotype at each SNP, but polymorphism at only SNP V122I in DNase 1L1 was found in Caucasian groups including Germans and Turks; thus a Caucasian‐specific allele was identified. The DNase 1L1 and 1L2 genes show relatively low genetic diversity with regard to these non‐synonymous SNPs. The level of activity derived from the V122I, Q170H and D227A substituted DNase 1L1 corresponding to SNPs was similar to that of the wild‐type, whereas replacement of the Asp residue at position 197 in the DNase 1L2 protein with Ala, corresponding to SNP D197A, reduced its activity greatly. Thus, SNP V122I in DNase 1L1 exhibiting polymorphism exerts no effect on the catalytic activity, and furthermore SNP D197A in DNase 1L2, affecting its catalytic activity, shows no polymorphism. These findings permit us to postulate that the non‐synonymous SNPs identified in the DNase 1L1 and 1L2 genes may exert no influence on the activity levels of DNases 1L1 and 1L2 in human populations.
Generation of methane from textile desizing liquors
Authors: Opwis Klaus , Mayer‐Gall Thomas , Schollmeyer Eckhard , Dammer Christoph , Titscher Tanja , Nickisch‐Hartfiel Anna , Grün Oliver , Spurk Christoph , Schloderer Christine , Köppe Axel , Dörfler Christian , Bachus Herbert 
Published: May 2010

AbstractA new strategy for the biological transformation of sugar‐containing wastewaters from the textile desizing process to biogas was developed. Here, industrial liquors were separated from the following washing step by squeezing the impregnated fabrics after desizing. These waters exhibit a chemical oxygen demand of 40 g/L and allow a direct use in microbial biogas reactors without further treatment or accumulation. After reaching balanced conditions, the microbes continuously produce biogas. Moreover, the chemical oxygen demand can be reduced up to 75%. This new technology seems to be practicable and even attractive for small‐ and medium‐sized enterprises with an annual cotton production down to 2000 t. At this stage, a reliable eco‐balance of the overall process is still pending. Further investigations will be carried out soon.
Oligodendrocyte precursors originate in the parabasal band of the basal plate in prosomere 1 and migrate into the alar prosencephalon during chick development
Authors: Garcia‐Lopez Raquel , Martinez Salvador 
Published: May 2010

AbstractOligodendrocytes are the myelin‐forming cells in the central nervous system of vertebrates. Oligodendrocyte precursors arise from multiple restricted foci distributed along the antero‐posterior axis of the developing brain. In chick and mouse embryos, oligodendrocyte precursors of the anterior forebrain emerge from neuroepithelial cells of the subpallium and migrate tangentially to invade the entire telencephalon (Olivier et al. (2001) Development 128:1757–1769). In the diencephalon, oligodendrocyte neuroepithelial precursors seem to be mainly located in the basal plate of caudal prosomeres, but very little is known about their distribution and maturation at later stages of embryonic development. Thus, in this work, we studied the origin and migration of oligodendrocyte precursos in the diencephalon of quail‐chick chimeras. Homotopic and homochronic grafts demonstrated that, during embryonic development, diencephalic oligodendrocytes emerge from a common neuroepithelial domain in the basal plate of prosomere 1 and migrate tangentially, invading the dorsal regions of the diencephalic prosomeres and the telencephalon. © 2010 Wiley‐Liss, Inc.
Astrocytes retain their antioxidant capacity into advanced old age
Authors: Liddell Jeff R. , Robinson Stephen R. , Dringen Ralf , Bishop Glenda M. 
Published: May 2010

AbstractOxidative stress has been implicated in the progression of ageing and in many age‐related neurodegenerative conditions. Astrocytes play a major role in the antioxidant protection of the brain, yet little is known about how the antioxidant defenses of astrocytes change across the lifespan. This study assessed the antioxidant capacity and glutathione metabolism of astrocytes cultured from the brains of neonatal (<24 h old), mature (12‐month‐old), old (25‐month‐old), and senescent (31‐month‐old) C57BL/6J mice. When exposed to 100 μM hydrogen peroxide, mature, old, and senescent astrocytes cleared the peroxide ∼30% more slowly than neonatal astrocytes. This difference persisted when catalase was inhibited by 3‐aminotriazole, but was abolished when glutathione was depleted by application of buthionine sulfoximine, suggesting a deficit in the glutathione system. Correspondingly, the specific glutathione reductase activity of mature, old, and senescent astrocytes was ∼30% lower than that of neonatal cultures, whereas no age‐related change was observed in the specific activities of glutathione peroxidase, catalase, or in total antioxidant capacity. In addition, the specific rate of glutathione export was almost identical in mature, old, and senescent astrocytes, but was more than double that of neonatal astrocytes. These results indicate that the antioxidant capacity and glutathione metabolism of astrocytes are preserved from mature adulthood into senescence. It is concluded that the oxidative stress seen in ageing brains is likely due to factors extrinsic to astrocytes, rather than to an impairment of the antioxidative functions of astrocytes. © 2010 Wiley‐Liss, Inc.
Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities
Authors: Tosun Duygu , Siddarth Prabha , Toga Arthur W. , Hermann Bruce , Caplan Rochelle 
Published: May 2010

AbstractIn this study, we used surface‐based morphometry to examine whether age‐related changes in gray matter tissue thickness and depth of sulcal regions at high spatial resolution across the cortex differed in children with childhood absence epilepsy (CAE) compared to healthy control subjects. In addition, the possibility of variable brain‐cognition relationships in the CAE compared to the control group was investigated. The main findings of this study are as follows: (1) From the developmental perspective, children with CAE did not demonstrate the normal regional age‐related changes involving a decrease in cortical thickness and increase in sulcal depth. (2) None of the seizure variables, including age of onset, seizure frequency, and AEDs had a significant effect on the association between age and cortical morphometry measures in the CAE population. (3) Even though the CAE group had mean VIQ and PIQ scores in the average range, our findings suggest that they use different brain regions to perform these cognitive functions compared to healthy controls. This first study on brain morphometry and cognition in children with childhood absence seizures has important implications for advancing our understanding of brain development and cognitive comorbidity in CAE, as well as for revisiting the clinical notion that CAE is a benign disorder. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
Emotional memories are resilient to time: Evidence from the parietal ERP old/new effect
Authors: Weymar Mathias , Löw Andreas , Hamm Alfons O. 
Published: May 2010

AbstractEmotional memories can be extremely robust and long‐lasting and can contribute to the development of anxiety disorders. Despite tremendous work on neural responses underlying the memory formation of emotional events, less is known about long‐term retention. In the present study, behavioral and electrophysiological measures were used to investigate long‐term recognition memory for emotional (unpleasant and pleasant) and neutral pictures after two retention intervals (1 week vs. 1 year) in 21 male subjects. The results show enhanced recognition performance for emotional relative to neutral pictures for both test delays. On the neural side, the retrieval of emotional pictures compared to neutral pictures was accompanied after 1 week by an enhanced old/new effect (500–800 ms), originating in the parietal cortex. After 1‐year retention delay, only unpleasant but not pleasant pictures were different from neutral pictures in the recollection‐sensitive ERP component. Analysis of the subjective awareness (confidence ratings) during recognition indicated that behavioral and electrocortical response patterns were exclusively driven by high confidence responses, an indication for recollection‐based recognition. These results suggest that high arousing emotional memories were highly consistent over time relative to neutral memories. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
(How) Does the HR strategy support an innovation oriented business strategy? An investigation of institutional context and organizational practices in Indian firms
Authors: Cooke Fang Lee , Saini Debi S. 
Published: May 2010

AbstractThis paper investigates how human resources are managed in firms of different ownership forms in India and the extent to which strategic human resource management (hereafter strategic HRM) techniques have been adopted to support an innovation‐oriented business strategy. Based on a qualitative study of 54 Indian managers from different firms, this study highlights the Indian institutional context for strategic HRM. It reveals the extent to which the Western approach to and configuration of high‐commitment/performance models of HR practices may differ from those found in Indian firms. This study also has a number of practical implications for HR professionals, HR practices, and organizations in the global context. © 2010 Wiley Periodicals, Inc.
Outcomes of intention to quit of Indian IT professionals
Authors: Krishnan Sandeep K. , Singh Manjari 
Published: May 2010

AbstractIntention to quit has been getting attention in the context of employee attrition, with focus on its antecedents. A related aspect that needs attention is the outcome of intention to quit, where little research has occurred, especially in the Indian context. The present study explores performance orientation, organizational deviance, and organizational citizenship behavior as outcomes of intention to quit of Indian IT professionals. These factors become critical in the context of human resource management because employees who want to quit may become less productive or even dysfunctional for the organization. Interviews and a questionnaire‐based survey were used in this research. The survey was conducted using software professionals with work experience of less than four years, with the results based on 533 responses. The initial results show that as hypothesized, intention to quit does lead to less performance orientation, higher organizational deviance, and less organizational citizenship behavior. Further, exploration using structural equation modeling shows that performance orientation mediates the relationships between intention to quit and organizational citizenship behavior as well as between intention to quit and organizational deviance. This study's findings imply that organizations need to understand that employees with a high intention to quit can prove costly from multiple dimensions. © 2010 Wiley Periodicals, Inc.
Linking emotional dissonance and organizational identification to turnover intention and emotional well‐being: A study of medical representatives in India
Authors: Kumar Mishra Sushanta , Bhatnagar Deepti 
Published: May 2010

AbstractInfluencing customers' perception of service quality through service interaction is becoming imperative for organizations to sustain competitive advantage. As a result, the critical challenge before many organizations is to retain employees in service occupations and promote their well‐being. This study examined the relationship of organizational identification and emotional dissonance with turnover intention and well‐being among a sample of 468 medical representatives in the Indian pharmaceutical industry. Drawing from the conservation of resource theory, this study shows that apart from its direct effect, emotional dissonance has a mediating effect on the relationship of organizational identification with turnover intention and emotional well‐being. Contributions of this study to the theory and practice of human resource management (HRM) are discussed. © 2010 Wiley Periodicals, Inc.