bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Biological Evaluation of Aza‐C‐disaccharides: (1→ 6), (1→4), and (1→1) Linked Sugar Mimics.
Authors: JOHNS B. A. , PAN Y. T. , ELBEIN A. D. , JOHNSON C. R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a Tetrasaccharide Analogue Related to the Repeating Unit of the Antigen from Klebsiella Type 2.
Authors: MISRA A. K. , ROY N. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Indole Phytoalexins Brassinin and Cyclobrassinin via (1‐( tert‐Butoxycarbonyl)indol‐3‐yl)methyl Isothiocyanate as the Key Biomimetic Intermediate.
Authors: KUTSCHY P. , ACHBERGEROVA I. , DZURILLA M. , TAKASUGI M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of a New Class of Polynuclear Pyridinethione Nucleosides.
Authors: ELGEMEIE G. E. H. , ATTIA A. M. E. , FATHY N. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Some Pyrrolo(2,3‐d)pyrimidine Isodideoxynucleosides of (S, S)‐Stereochemistry.
Authors: TALEKAR R. R. , WIGHTMAN R. H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sphingolipid and Sterols of the Sponge Callyspongia spinosissima
Authors: AGRAWAL S. , GARG H. S. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5′′,5′′′′‐(2′′′′,2′′′′′‐Dihydroxydibenzyl)diuvaretin and 5′′′,3′′′′‐(2′ ′′′,2′′′′′‐Dihydroxydibenzyl)iso‐diuvaretin: Two Novel C‐Dibenzylated Dihydrochalcones from the Root Extract of Xylopia africana (Benth.) Oliver (Annonaceae).
Authors: ANAM E. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a Novel Biotinyl Derivative and Its Application to Non‐ Radioactive Labeling of DNA.
Authors: YAMAMOTO I. , ARAI Y. , FUKUDA T. , Y‐TAKIHARA K. , AZUMA J. , MUKAI T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Syntheses and Evaluation of Compounds in the 8‐ Desmethylepothilone A Series: Some Surprising Observations Regarding Their Chemical and Biological Properties.
Authors: BALOG A. , BERTINATO P. , SU D.‐S. , MENG D. , SORENSEN E. , DANISHEFSKY S. J. , ZHENG Y.‐H. , CHOU T.‐C. , HE L. , HORWITZ S. B. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Absolute Stereochemistry of the New Zealand Shellfish Toxin Gymnodimine.
Authors: STEWART M. , BLUNT J. W. , MUNRO M. H. G. , ROBINSON W. T. , HANNAH D. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spectroscopic, Antifungal, and Antibacterial Studies of Some Manganese Heterochelates
Authors: FAHMI N. , SINGH R. V. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Activation Process for Autocatalytic Electroless Deposition on Silicon Substrates.
Authors: KARMALKAR S. , SRIDHAR D. , BANERJEE J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Atomic Environment Classification of the Tetragonal “Intermetallic” Structure Types
Authors: DAAMS J. L. C. , VILLARS P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Properties of Al‐Based Icosahedral Alloys
Authors: BAHADUR D. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Four Case Studies in the Development of Biotransformation‐Based Processes
Authors: MCCAGUE R. , TAYLOR S. J. C. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Arylboronates via Palladium‐Catalyzed Cross‐Coupling Reaction of Alkoxydiboron with Aryl Halides or Triflates
Authors: ISHIYAMA T. , MIYAURA N. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Large‐Scale Synthesis of Unnatural Amino Acids
Authors: AGER D. J. , FOTHERINGHAM I. G. , LANEMAN S. A. , PANTALEONE D. P. , TAYLOR P. P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solid‐Phase Synthesis of Glycopeptides: Immunological Studies with T Cell Stimulating Glycopeptides
Authors: KIHLBERG J. , ELOFSSON M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Enantiomerically Pure Nucleosides
Authors: BRAY B. L. , GOODYEAR M. D. , PARTRIDGE J. J. , TAPOLCZAY D. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Protonation in Fragrance Synthesis
Authors: FEHR C. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Gear Effect: Self‐Organization of Structural Fragments Induced by Release of Nonbonded Interactions ‐ Consequences in Reactivity. Part 2. Other Models, Alkyl Substituted Ethylenes, Arenes and Heteroarenes, Incidence on Chemical Reactivity, Creation of Gear Effect
Authors: METZGER J. V. , CHANON M. C. , ROUSSEL C. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The response of the local immunoglobulin system to malignant lesions of the stomach: A new diagnostic test
Authors: Levy Mitchell , Petreshock Edward P. , Mandell Charlotte , Deysine Maximo , Katzka Irwin , Aufses Arthur H. 
Published: August 2010

AbstractThe response of the local secretory immunoglobulin system to tumor antigens was studied in 71 patients suspected of harboring a gastric malignancy. Gastric aspirates were obtained by fiberoptic endoscopy and measured on single radial immunodiffusion plates (Behring Diagnostics). Patients with malignant neoplasms of the stomach were divided into Type I and Type II lesions, based on the extent and stage of the disease. Secretory IgA titers were elevated in all patients with a Type I malignant tumor confirmed by histologic examination; mean 43.8 mg/100 (SD ± 40.6 mg/100). Patients with Type II malignant tumors, benign lesions or normal controls had significantly lower IgA titers; mean 6.1 mg/100 (SD ± 3.7 mg/100). This leads us to believe that the host's response to malignant cells of the gastrointestinal system is an altered and elevated secretion of IgA. Evaluation of local immunoglobulin titers may be of value when used in conjunction with other diagnostic modalities in determining the nature of gastrointestinal lesions, particularly when the lesion is not metastatic or massively involving the gastric wall.
CEA levels in patients with colorectal polyps
Authors: Doos W. G. , Wolff William I. , Shinya H. , DeChabon A. , Stenger R. J. , Gottlieb L. S. , Zamcheck N. 
Published: August 2010

AbstractPreoperative plasma CEA levels were measured in 93 selected patients with histologically defined colorectal adenomata removed at fibroptic colonoscopy in order to determine whether CEA levels are elevated in patients with colonic polyps, or vary with different histologic patterns. None of the patients had inflammatory bowel disease, previous history of carcinoma, or evidence of liver disease. Fifteen percent of the patients had elevated CEA levels (≥2.5 ng/ml; Hansen method), and two‐thirds of these were between 2.5 and 4.0 ng/ml. Increased association of elevated CEA levels was noted with old age, villous adenomas (2‐to 4‐fold), and increased tumor size ((2.3‐cm diameter; 2‐fold), but not with foci of dysplasia or carcinoma in situ as such. One‐half (7/14) of the patients with elevated CEA levels showed the following: two patients had villous tumors with carcinoma in situ, one had a villous adenoma, two had mixed villous and tubular adenomas (with a high proportion of villous pattern), and two were subsequently shown to have carcinoma elsewhere in the colon. It is uncertain that the polyps were the source of the elevated circulating CEA levels; other factors including smoking and patient selection need to be considered. This preliminary study suggests that patients with colorectal adenomata and elevated circulating CEA may be at higher risk for the development of carcinoma. Further follow‐up studies of the malignant potential of the polyp‐bearing colon are essential.
Cellular imunity in neoplasia: Antigen and mitogen responses in patients with bronchiogenic carcinoma
Authors: Rees John C. , Rossio Jeffrey L. , Wilson Henry E. , Minton John P. , Dodd Matthew C. 
Published: August 2010

AbstractCellular immune responses of patients with histologically confirmed lung carcinoma were assessed in vivo using cutaneous response and in vitro with a microlymphocyte blastogenic transformation (LBT) assay. In addition, correlation of the cutaneous response with the migration inhibitory factor (MIF) assay and LBT response was examined. The results indicated that cutaneous responses seen in patients with cancer of the lung were consistently lower than similar responses in normal controls (p < 0.001). Similarily, the percentage of positive cutaneous responses seen with patients included in this study was lower than the frequencies reported by others. Stimulation of cells from lung cancer patients by PHA‐M was also depressed when compared to similar lymphocytic responses in normal volunteers (p < 0.001). The correlation between cutaneous response to tuberculin and the in vitro assays was high. The few instances of disparity demonstrate the need to utilize more than one assay in evaluating cellular immune functions. These data would support the work of ther that indicate a depression of cellular immunity in advanced malignancy.
Adenocarcinoma of the small intestine arising in crohn's disease: Demonstration of a tumor‐associated antigen in invasive and intraepithelial components
Authors: Newman Robert D. , Bennett Sidney J. , Pascal Robert R. 
Published: August 2010

AbstractA segment of small intestine surgically removed from a man with intestinal obstruction was found to have coexisting regional enteritis and an invasive adenocarcinoma associated with an area of intraepithelial neoplasia. The cells of the adenocarcinoma and the intraepithelial neoplasia contained a tumor‐associated surface antigen capable of reacting with an antiserum prepared against a colonic carcinoma. The importance of thorough sampling of specimens of regional enteritis in accurate reporting of the incidence of carcinoma is stressed, as is the use of immunohistologic techniques as an adjunct to the morphologic diagnosis of preinvasive neoplasia.
Lymphographic demonstration of cyclic changes in lymph node size during pel‐epstein fever
Authors: Scanlon Gerard T. , Castellino Ronald A. , Rudders Richard 
Published: August 2010

AbstractPel‐Epstein fever cycles, consisting of 1–2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, the waxing and waning of lymph nodes in tempo with the fever cycle in Hodgkin's disease have never before been documented by lymphography. The alterations we verified radiographically resemble cyclic swings in classic autoimmune diseases. Speculations are offered regarding the observed changes.
Induction of pulmonary metastases in both immune and nonimmune mice: Effect of the removal of a transplanted primary tumor
Authors: Wexler Hilda , Chretien Paul B. , Ketcham Alfred S. , Sindelar William F. 
Published: August 2010

AbstractIn mice bearing a benzypyrene‐induced fibrosarcoma tumor, the survival was determined of intravenously injected tumor cells at various intervals after previous immunization of experimental animals by induction and subsequent excision of a transplanted primary tumor in the soft tissues of the leg. Seven days after induction of a transplanted primary tumor, I.V. tumor cells produced fewer pulmonary metastases in immunized mice than in nonimmunized mice. When tumor cells were incoulated I.V. immediately following amputation of the transplanted primary tumor, the number of pulmonary metastases in the immunized and nonimmunized animals were similar; however, 6 hours, 7 days and 14 days after primary tumor excision, I.V. inoculated tumor cells produced a higher incidence of lung metastases in the immunized than in the nonimmunized mice. This increased survival of I.V. tumor cells following excision of the transplanted primary tumor may have relevance to the development of metastases after eradication of certain primary tumors in humans.
Childhood hodgkin's disease in israel: A study of 17 cases
Authors: Aghai E. , Brenner H. , Ramot B. 
Published: August 2010

AbstractA study of 17 children suffering from Hodgkin's disease (H.D.) is presented. The special ethnic distribution with predominance in Arab and Oriental Jewish children is noted. A high incidence of mixed cellularity histology in Arab children is emphasized. A conservative approach to therapy, i.e. extended field regional radiotherapy only, resulted in a long first complete remission period in lymphocyte predominance and nodular sclerosis H.D. Stages IA and IIA. All children in Stage IIIB and IV were treated by six courses of combined chemotherapy, and were maintained either on chlorambucil and vinblastine or on MOPP. Patients with mixed cellularity H.D. Stage IIA and all patients in Stage IIIA were treated by four courses of MOPP after the completion of extended regional radiotherapy. The 5 children who did not receive the scheduled treatment died. The remaining 12 are well, with a survival of 8 to 104 months.
Hydrogen Atom Transfer Experiments Provide Chemical Evidence for the Conformational Differences between C‐ and O‐Disaccharides
Authors: León Elisa I. , Martín Angeles , Peréz‐Martín Inés , Quintanal Luis M. , Suárez Ernesto 
Published: August 2010

AbstractThe glycopyran‐6‐O‐yl radical promoted hydrogen atom transfer reaction (HAT) between the two pyranose units of α‐D‐Manp‐(1→4)‐α‐D‐Glcp and α‐D‐Manp‐(1→4a)‐4a‐carba‐α‐D‐Glcp disaccharides provides supporting chemical evidence for the conformational differences between O‐ and C‐glycosyl compounds. In the O‐disaccharide the 6‐alkoxyl radical, generated under oxidative or reductive conditions, abstracts exclusively the hydrogen at C‐5′ via a completely regioselective 1,8‐HAT reaction. This may be attributable to the conformational restriction of the glycosidic and aglyconic bonds due principally to steric and stereoelectronic effects. On the contrary, very little regioselectivity is observed in the homologous C‐disaccharide and a mixture of compounds generated by 1,5‐, 1,6‐, and 1,8‐HAT processes where the abstraction occurs at hydrogen atoms positioned at C‐4a, C‐1′, and C‐5′, respectively, has been obtained. This study has been extended to simpler O‐ and C‐glycosides, where the aglycon was a straight n‐alkyl alcohol tether of five atoms; in general, all of the results obtained are shown to be consistent with a major conformational flexibility of the C‐glycosidic bond.
An Anomeric Effect Drives the Regiospecific Ring‐Opening of 1,3‐Oxazolidines under Acetylating Conditions
Authors: Martínez R. Fernando , Ávalos Martín , Babiano Reyes , Cintas Pedro , Jiménez José L. , Light Mark E. , Palacios Juan C. , Pérez Esther M. S. 
Published: August 2010

AbstractA series of oxazolidines derived from tris(hydroxymethyl)aminomethane (TRIS; 1), have been prepared efficiently. Geometries optimized at the B3LYP/6‐31G* level of theory, along with the crystal data of compounds 9 and 12 and NOESY correlations, point to a strong endo anomeric effect that anchors a preferential conformation and subsequently dictates the completely regioselective ring‐opening of the oxazolidine moiety under acetylating conditions to afford imines instead of N‐acetyloxazolidines. This process was monitored by 1H NMR spectroscopy, corroborated by synthesis, and rationalized by the intermediacy of an iminium ion. Oxazolidine–imine equilibria are also described for TRIS and other aminopolyols. The equilibria are shifted to the heterocyclic partner as the number of reactive hydroxy groups increases. The structures of an unprotected imine (31) and a per‐O‐acetylated derivative (43) have also been established by crystallographic analyses.
Determination of the binding constants of modafinil enantiomers with sulfated β‐cyclodextrin chiral selector by capillary electrophoresis using three different linear plotting methods
Authors: Al Azzam Khaldun M. , Saad Bahruddin , Aboul‐Enein Hassan Y. 
Published: August 2010

AbstractBinding constants for the enantiomers of modafinil with the negatively charged chiral selector sulfated‐β‐CD (S‐β‐CD) using CE technique is presented. The calculations of the binding constants employing three different linearization plots (double reciprocal, X‐reciprocal and Y‐reciprocal) were performed from the electrophoretic mobility values of modafinil enantiomers at different concentrations of S‐β‐CD in the BGE. The highest inclusion affinity of the modafinil enantiomers were observed for the S‐enantiomer–S‐β‐CD complex, in agreement with the computational calculations performed previously. Binding constants for each enantiomer–S‐β‐CD complex at different temperatures, as well as thermodynamic parameters for binding, were calculated. Host–guest binding constants using the double reciprocal fit showed better linearity (r2>0.99) at all temperatures studied (15–30°C) and compared with the other two fit methods. The linear van't Hoff (15–30°C) plot obtained indicated that the thermodynamic parameters of complexation were temperature dependent for the enantiomers.