bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glial fibrillary acidic protein as a marker of axonal damage in chronic neuropathies
Authors: Notturno Francesca , Capasso Margherita , Delauretis Angelo , Carpo Marinella , Uncini Antonino 
Published: July 2009

AbstractWe evaluated serum glial fibrillary acidic protein (GFAP) levels by enzyme‐linked immunosorbent assay (ELISA) in controls (n = 30) and in patients with chronic sensory‐motor axonal neuropathy (CSMAN) (n = 30), chronic inflammatory demyelinating polyneuropathy (CIDP) (n = 30), multifocal motor neuropathy (MMN) (n = 30), and primary muscular spinal atrophy (PMSA) (n = 15). GFAP levels, expressed as optical density, were increased in CSMAN (median = 1.05) compared to controls (median = 0.41; P < 0.05) and CIDP (median = 0.53, P < 0.05). They were also increased in PMSA (median = 0.99) compared to controls (P < 0.05) and MMN (median = 0.66; P < 0.05). To differentiate CSMAN from CIDP and PMSA from MMN, we applied a cutoff of GFAP levels at 0.66, and we obtained good sensitivity and specificity. In neuropathies, serum GFAP correlated with summated sensory nerve action potential amplitudes (r = −0.57; P = 0.0006) and disease severity (r = 0.37; P = 0.0011). Thus, we propose serum GFAP as a marker of axonal damage and severity in chronic neuropathies. Muscle Nerve 40: 50–54, 2009
Screening for pompe disease using a rapid dried blood spot method: Experience of a clinical diagnostic laboratory
Authors: Goldstein Jennifer L. , Young Sarah P. , Changela Mohita , Dickerson Gwen H. , Zhang Haoyue , Dai Jian , Peterson Denise , Millington David S. , Kishnani Priya S. , Bali Deeksha S. 
Published: July 2009

AbstractPompe disease (acid maltase deficiency; glycogen storage disease type II) is caused by deficiency of the lysosomal enzyme acid alpha‐glucosidase (GAA). Our clinical laboratory began to offer a fluorometric dried blood spot (DBS)‐based GAA activity assay for Pompe disease in 2006 after the FDA approved GAA enzyme replacement therapy in April of that year. The purpose of this study was to examine the experience of our clinical laboratory in using this assay. Over a 2‐year period, we received samples for the DBS GAA assay from 891 patients referred for possible Pompe disease, of whom 111 (12.5%) patients across the disease spectrum who had results in the affected range. The majority of the patients were referred by neurologists and geneticists. When available, we correlated the results obtained through DBS GAA activity assay with the results from a second DBS, or a second tissue (cultured skin fibroblasts or muscle biopsy). In our experience, the DBS GAA activity assay provides a robust, rapid, and reliable first tier test for screening patients suspected of having Pompe disease. Muscle Nerve 40: 32–36, 2009
Sarcoplasmic redistribution of nuclear TDP‐43 in inclusion body myositis
Authors: Salajegheh Mohammad , Pinkus Jack L. , Taylor J.Paul , Amato Anthony A. , Nazareno Remedios , Baloh Robert H. , Greenberg Steven A. 
Published: July 2009

AbstractThe nucleic acid binding protein TDP‐43 was recently identified in normal myonuclei and in the sarcoplasm of inclusion body myositis (IBM) muscle. Here we found TDP‐43 sarcoplasmic immunoreactivity in 23% of IBM myofibers, while other reported IBM biomarkers were less frequent, with rimmed vacuoles in 2.8%, fluorescent Congo red material in 0.57%, SMI‐31 immunoreactivity in 0.83%, and focal R1282 beta‐amyloid immunoreactivity in 0.00% of myofibers. The presence of as little as >1% of myofibers with nonnuclear sarcoplasmic TDP‐43 was highly sensitive (91%) and specific (100%) to IBM among 50 inflammatory myopathy patient samples, although some patients with hereditary inclusion body myopathies and myofibrillar myopathy also had sarcoplasmic TDP‐43. TDP‐43 mutations were sought, and none were identified. TDP‐43 could be one of many nucleic acid binding proteins that are abnormally present in IBM sarcoplasm. They could potentially interfere with the normal function of extranuclear RNAs that maintain myofiber protein production. Muscle Nerve 40: 19–31, 2009
Diagnostic criteria for late‐onset (childhood and adult) pompe disease
Authors:   AMERICAN ASSOCIATION OF NEUROMUSCULAR & ELECTRODIAGNOSTIC MEDICINE
Published: July 2009

AbstractThe diagnosis of late‐onset (childhood and adult) Pompe disease can often be challenging, as it is a rare disease and the heterogeneous clinical presentation can mimic the presentation of other neuromuscular disorders. The objective was to develop a consensus‐based algorithm for the diagnosis of late‐onset Pompe disease. A systematic literature search was conducted, and an expert panel composed of neuromuscular specialists and individuals with expertise in Pompe disease reviewed the literature and convened for consensus development. An algorithm for the diagnosis of late‐onset Pompe disease was created. Patients presenting with either a limb‐girdle syndrome or dyspnea secondary to diaphragm weakness should undergo further testing, including evaluations of muscle strength, motor function, and pulmonary function. A blood‐based acid α‐glucosidase (GAA) enzyme activity assay is the recommended tool to screen for GAA enzyme deficiency. The diagnosis should be confirmed by a second test: either a second GAA enzyme activity assay in another tissue or GAA gene sequencing. Muscle Nerve 40:149–160, 2009
The role of incretin‐based therapies in the management of type 2 diabetes
Authors: Russell‐Jones D 
Published: July 2009

AbstractIn patients with type 2 diabetes mellitus (T2DM), goals for blood glucose and other cardiovascular risk factors, such as blood pressure and body weight, can be difficult to achieve. Recent clinical trials indicate that incretin‐based therapies—dipeptidyl peptidase‐4 inhibitors and glucagon‐like peptide‐1 (GLP‐1) agonists—help to achieve glycaemic goals and are generally well tolerated, with a low prevalence of hypoglycaemia. GLP‐1 agonists also improve weight, blood pressure and markers of β‐cell function. Addition of an incretin‐based agent may be appropriate for selected patients with T2DM and unsatisfactory glycaemic control on conventional therapies. Copyright ©2009 John Wiley & Sons.
Theoretical analysis of aggregation in block‐copolymer films: The optical signature
Authors: Giro Ronaldo , Davila Liliana Y. A. , Machado Angelita M. , Caldas Marilia J. , Akcelrud Leni 
Published: July 2009

AbstractWe focus this work on the theoretical investigation of the block‐copolymer poly[oxyoctyleneoxy‐(2,6‐dimethoxy‐1,4phenylene‐1,2‐ethinylene‐phenanthrene‐2,4diyl) named as LaPPS19, recently proposed for optoelectronic applications. We used for that a variety of methods, from molecular mechanics to quantum semiempirical techniques (AM1, ZINDO/S‐CIS). Our results show that as expected isolated LaPPS19 chains present relevant electron localization over the phenanthrene group. We found, however, that LaPPS19 could assemble in a π‐stacked form, leading to impressive interchain interaction; the stacking induces electronic delocalization between neighbor chains and introduces new states below the phenanthrene‐related absorption; these results allowed us to associate the red‐shift of the absorption edge, seen in the experimental results, to spontaneous π‐stack aggregation of the chains. © 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2010
Validated quantitation method for a peptide in rat serum using liquid chromatography/high‐field asymmetric waveform ion mobility spectrometry
Authors: Klaassen Tobias , Szwandt Simon , Kapron James T. , Roemer Axel 
Published: July 2009

AbstractThe analysis of peptides presents serious challenges for bioanalytical scientists including low total ion current and non‐selective fragmentation during tandem mass spectrometry (MS/MS). During method validation of a peptide in rat serum matrix some interferences could not be easily removed and thus prevented accurate and precise measurement. These problems associated with peptide quantitation were resolved by using FAIMS (high‐Field Asymmetric waveform Ion Mobility Spectrometry). This selectivity‐enhancing technique filters out matrix interferences, and the resulting pseudo‐selected reaction monitoring (pseudo‐SRM) chromatograms were nearly free from interferences. Control blank matrix samples contained an acceptable level of interference (only 7% signal as compared to the lower level of quantitation). Chromatographic peaks were easily, accurately and precisely integrated resulting in a validated liquid chromatography (LC)/FAIMS‐MS/MS method for the analysis of a peptide drug in rat serum according to United States Food and Drug Administration (US FDA) bioanalytical guidelines. These results confirm that new selectivity‐enhancing technologies aid the pharmaceutical industry in reliably producing acceptable pharmacokinetic data. Copyright © 2009 John Wiley & Sons, Ltd.
Resource subsidies across the land–freshwater interface and responses in recipient communities
Authors: Richardson John S. , Zhang Yixin , Marczak Laurie B. 
Published: July 2009

AbstractFluxes of resource subsidies, such as terrestrial leaf litter to streams and adult aquatic insects to riparian predators, are examples of important links between adjacent ecosystems. The importance of these cross‐ecosystem resource flows from donor systems to recipient consumers is increasingly recognized. Streams, especially small streams with their high edge ratio with the terrestrial system, provide excellent models for the study of subsidies and a large portion of this literature has been produced by aquatic scientists. Field experiments manipulating flows between small streams and their riparian areas (e.g. leaf litter, terrestrial invertebrates, and adult aquatic insects to riparian areas) have indicated that consumers in streams and riparian areas are highly dependent upon such subsidies and the value of the subsidies are further modified by patterns of retention and pathways of use. Experiments typically indicate rapid growth or demographic responses by consumers, indicating these populations are resource limited or at levels of incipient population limitation, and can capitalize on short‐term resource pulses. More press manipulations are still necessary to determine the dynamical consequences of subsidies for recipient communities. The nature of the subsidy (e.g. species of litter or invertebrates) and its timing are also important details that need further study. Finally, there are opportunities to consider the evolution of life cycle timing (modelling), interception strategies by recipient populations and short‐term and long‐term responses of communities. Copyright © 2009 John Wiley & Sons, Ltd.
Epistemological norms and companion meanings in science classroom communication
Authors: Lundqvist Eva , Almqvist Jonas , Östman Leif 
Published: July 2009

AbstractIn this paper, we describe two central epistemological norms related to the importance of making investigations and to scientific language and its logic. These norms have been identified in empirical material consisting of 200 video‐recorded lessons in three different science classes. With regard to the learning of science and socialization, we discuss and problematize these norms in the context of science learned at school and the nature of science. A methodological approach has been developed and used to analyze and identify the role that teachers' actions play in which epistemology students adopt in their meaning making and to highlight which view of science this usage represents. The approach consists of a combination of three methodologies: practical epistemology analyses, epistemological move analyses, and analyses of companion meanings. This combination produces communication analysis of companion meanings. The theory is based on pragmatism, sociocultural approaches to learning, and the later works of Wittgenstein. The companion meanings described in the empirical material indicate that if students learn the identified norms without any explicit problematization, they will only view science as rational and inductive in character and exclude alternative views from the practice. © 2009 Wiley Periodicals, Inc. Sci Ed 93:859–874, 2009
Ontology‐based ubiquitous monitoring and treatment against depression
Authors: Hu Bin , Hu Bo , Wan Jizheng , Dennis Majoe , Chen Hsiao‐Hwa , Li Lian , Zhou Qingguo 
Published: July 2009

AbstractMental health care is a major cost to all EU nations, and in many case, it results in additional costs to a country's economy due to the lost of productivity and concerns at the societal level. Cognitive behaviour therapy (CBT) is by far the treatment of choice for mental disorders such as depression, anxiety disorders, eating disorders, chronic insomnia, etc. Although effective, CBT suffers from a lack of accessibility and personalisation. In this paper, we proposed an ontology‐enhanced ubiquitous monitoring and treatment model for the purpose of assisting people to overcome the challenges of mental disorders. We first presented a context ontology for mental disorders as the basis upon which semantics‐enhanced methods are developed for gathering, formalising and manipulating patients' data. We implemented the proposed framework to facilitate online CBT, for treating depression at the current stage, which combines together talk/chat/messaging services, helps in retrieving neurofeedback, and supports collaborative diagnosis when necessary. An online statistic report was also integrated into our system. Finally, the paper discussed the proposed framework by comparing it against relevant research in the field and elaborated on possible further research directions. Copyright © 2009 John Wiley & Sons, Ltd.
Cross‐layer design for MIMO systems over spatially correlated and keyhole Nakagami‐mfading channels
Authors: Qi Jian , Aïssa Sonia , Maaref Amine 
Published: July 2009

AbstractCross‐layer design is a generic designation for a set of efficient adaptive transmission schemes, across multiple layers of the protocol stack, that are aimed at enhancing the spectral efficiency and increasing the transmission reliability of wireless communication systems. In this paper, one such cross‐layer design scheme that combines physical layer adaptive modulation and coding (AMC) with link layer truncated automatic repeat request (T‐ARQ) is proposed for multiple‐input multiple‐output (MIMO) systems employing orthogonal space‐‐time block coding (OSTBC). The performance of the proposed cross‐layer design is evaluated in terms of achievable average spectral efficiency (ASE), average packet loss rate (PLR) and outage probability, for which analytical expressions are derived, considering transmission over two types of MIMO fading channels, namely, spatially correlated Nakagami‐mfading channels and keyhole Nakagami‐mfading channels. Furthermore, the effects of the maximum number of ARQ retransmissions, numbers of transmit and receive antennas, Nakagami fading parameter and spatial correlation parameters, are studied and discussed based on numerical results and comparisons. Copyright © 2009 John Wiley & Sons, Ltd.
Syntheses and Crystal Structures of Two Chloro‐Bridged Coordination Polymers [Cd(BIM)Cl2]n and [Pb(BIM)Cl2]n
Authors: Hu Jing‐Jing , Jin Chuan‐Ming , Sun Ting‐Quan , Mei Hong‐Fei 
Published: July 2009

AbstractTwo novel coordination polymers, [Cd(BIM)Cl2]n (1) and [Pb(BIM)Cl2]n (2) [wherein BIM = bis(imidazol‐1‐yl)methane], were synthesized by the reactions of the BIM ligand with CdCl2 and PbCl2, respectively. They were characterized by elemental analyses, IR, TGA and X‐ray single‐crystal diffraction techniques. Single‐crystal X‐ray structure analyses showed there is a pseudooctahedral arrangement around the cadmium atom in the complex 1. It has a three‐dimensional network which contains one‐dimensional inorganic‐organic hybrid chains and μ2‐bridging chloride ligands. A rare pentacoordinate square‐pyramidal arrangement was adopted for the lead(II) atom in the complex 2, which has an unusual two‐dimensional layer structure of macrometallacycles crosslinked with the bridging Pb2Cl2 units. The metal atoms in both complexes were coordinated with two BIM ligands in cis arrangement and bridged by μ2‐bridging chloride ligands.
Cobalt(II) Tri‐tert‐butoxysilanethiolates with Bidentate Spacer Ligands
Authors: Pladzyk Agnieszka , Baranowska Katarzyna 
Published: July 2009

AbstractA new series of CoII tri‐tert‐butoxysilanethiolate complexes with bidentate N,N′‐ligands (L) such as pyrazine, quinoxaline and 4,4′‐bipy was obtained: for pyrazine and quinoxaline the complexes are binuclear {[Co{SSi(tBuO)3}2]2(μ‐L)} with metal atoms linked by an adequate heterocyclic base L. The use of 4,4′‐bipy resulted in a coordination polymer [Co{μ‐SSi(tBuO)3}{SSi(tBuO)3}(μ‐4,4′‐bipy)]n and two polymorphic forms of {[Co{SSi(tBuO)3}2]2(μ‐4,4′‐bipy)}. Pyridyl rings in one polymorph form a torsion angle of 0.57°, whereas a rotation about the linking C–C bond of 4,4′‐bipy in second polymorph is significant and results in a torsion angle of 72.4°. Complexes were analysed and characterised using elemental analysis, solid state IR and UV/Vis spectroscopy, and single‐crystal X‐ray analysis.
Synthesis, Crystal Structure, and Magnetic Properties of a Vanadium Oxide Nitride with Pseudobrookite‐type Structure
Authors: Nakhal S. , Hermes W. , Ressler T. , Pöttgen R. , Lerch M. 
Published: July 2009

AbstractA pseudobrookite‐type vanadium oxide nitride V3O4.61N0.27 has been prepared by reaction of vanadium sulfide with gaseous ammonia. Small amounts of nitrogen incorporated in the structure result in the stabilization of the pseudobrookite type not known from vanadium oxides. The crystal structure was investigated using X‐ray diffraction and X‐ray absorption spectroscopy. At temperatures above 630 °C, the oxide nitride decomposes to corundum‐type V2O3 and small amounts of monoclinic V3O5 and VO2(R) without a detectable amount of nitrogen. V3O4.61N0.27 shows Curie–Weiss behavior down to 3.1 K. The H = 10 kOe susceptibility data give no hint for magnetic ordering.
RETRACTED ARTICLE: Investigation of Frying Oil Quality Using VIS/NIR Hyperspectral Analysis
Authors: Yavari Alireza Ashkmehr , Hamedi M. , Haghbin S. 
Published: July 2009

AbstractTraditional chemical methods of analyzing frying oil quality are time‐consuming and not amenable to on‐line measurement. The main objective of this study was to evaluate quality changes of heated oils based on visible/near infrared spectral analysis using a hyperspectroradiometer. The reflectance spectra of the heated oils were analyzed within the range 400–1,750 nm. Acid value, total polar component, and viscosity of oil samples were used as indicators of different quality levels of oil. Partial least squares calibration models were developed for quantitative evaluations of these parameters. The R2 and root mean square error for each prediction were calculated to assess the prediction capability of calibration models. The study demonstrated that using the established calibration models, quality parameters could be predicted with R2 values over 0.92.
Adopting Preoperative Fasting Guidelines
Authors: Anderson Megan , Comrie Rhonda 
Published: July 2009

ABSTRACTIn 1999, the American Society of Anesthesiologists adopted preoperative fasting guidelines to enhance the quality and efficiency of patient care. Guidelines suggest that healthy, non‐pregnant patients should fast six hours from solids and two hours from liquids. Although these guidelines are in place, studies suggest that providers are still using the blanket statement “NPO after midnight” without regard to patient characteristics, the procedure, or the time of the procedure.Using theory to help change provider's beliefs may help make change more successful. Rogers' Theory of Diffusion of Innovations can assist in changing long‐time practice by laying the groundwork for an analysis of the benefits and disadvantages of proposed changes, such as changes to fasting orders, while helping initiate local protocols instead of additional national guidelines. AORN J 90 (July 2009) 73–80. © AORN, Inc, 2009.
The Perioperative Nurse's Role in Table‐Enhanced Anterior Total Hip Arthroplasty
Authors: Munro Cassendra A. 
Published: July 2009

ABSTRACTThe anterior approach to total hip arthroplasty (THA), when performed with the patient in the supine position, is enhanced by the use of a radiolucent, orthopedic table.This technique has numerous advantages: enhanced intraoperative fluoroscopy because of the patient's supine position on a radiolucent table, improved femoral exposure, and reduced soft tissue trauma. Criteria for patient selection is not limited as it may be for other arthroplasty techniques.The role of the perioperative nurse during an anterior THA is to ensure optimal function of the orthopedic table and provide safe patient care. A clear understanding of the surgical techniques used and the functions of the table are imperative. AORN J 90 (July 2009) 53–68. © AORN, Inc, 2009.
Starting a Health Care System Green Team
Authors: Mejia Elisa A. , Sattler Barbara 
Published: July 2009

ABSTRACTThe health care industry is often overlooked as a major source of industrial pollution, but as this becomes more recognized, many health care facilities are beginning to pursue green efforts. The OR is a prime example of an area of health care that is working to lessen its environmental impact.Nurses can play key roles in identifying areas of waste and presenting ideas about recovering secondary materials. For instance, although infection prevention measures encourage one‐time use of some products, nurses can investigate how to reprocess these items so they can be reused.This article examines how the efforts of a Green Team can affect a hospital's waste stream. A health care Green Team can facilitate a medical facility's quest for knowledge and awareness of its effect on the waste stream and environment. AORN J 90 (July 2009) 33–40. © AORN, Inc, 2009.
Telesurgery: Providing Remote Surgical Observations for Students
Authors: DeKastle Reuben 
Published: July 2009

ABSTRACTMeeting students' needs for a valuable experience in the OR presents many challenges especially in a non‐teaching hospital setting.Creating a means for students to observe surgery from a remote site can meet students' needs without causing scheduling, supervision, or patient care problems for the OR staff members who are hosting the students.Incorporating existing technology and recruiting staff members and physicians who are willing to participate and share their knowledge with students helps to create a valuable experience for all participants. AORN J 90 (July 2009) 93–101. © AORN, Inc, 2009.
Streamlining the OR
Authors: Bozzelli Mary Beth , Price Jayme 
Published: July 2009

ABSTRACTStreamlining the OR can increase physician and staff member satisfaction and improve efficiencies. Leaders at the West Florida Division for Healthcare Corporation of America took on the task of streamlining technology and processes for 16 facilities with the goal of surgical volume growth.After assessing the current processes, the team developed a plan to streamline the OR in four major areas. For each area, they paired technology with a process to accomplish the goal.The plan included improving the virtual supply inventory set up and case picking process, coupling the procedure groups and procedure set up with the scheduling process, improving the preference card set up and maintenance system, and pairing documentation with the pre‐admission and chart completion process. AORN J 89 (June 2009) 103–107. © AORN, Inc, 2009.