bluuebunny/crossref_metadata_2025_split huggingface dataset:
The arterialized saphenous venous flow‐through flap with dual venous drainage
Authors: Rozen Warren M. , Ting Jeannette W. C. , Gilmour Robert F. , Leong James 
Published: February 2012

AbstractBackground:Venous flow‐through flaps are well‐described options for small defects where donor site morbidity is undesirable or in areas where useful local veins are in close proximity to the defect, particularly in the extremities. However, higher rates of flap loss have limited their utility. The saphenous venous flap in particular has been widely sought as a useful flap, and while arterialization of this flap improved survival rates, congestion has remained a limiting feature. We describe report a modification in the design of saphenous venous flaps, whereby an arterialized flap is provided with a separate source of venous drainage, and demonstrate survival of substantially larger venous flaps than previously reported.Methods:In five consecutive patients, we describe three main modifications to the saphenous venous flap as previously described: (a) Using arterialized flaps only; (b) Reversing the flap to allow unimpeded flow during arterialization; and (c) Anastomosing additional vein(s) that are not connected to the central vein—especially at the periphery of the flap for true venous drainage.Results:There was a 0% complete flap loss rate (with only one case of superficial partial loss), and ultimately better survival than previous series of saphenous venous flaps described to date.Conclusion:The success of these techniques offers the potential to re‐establish flow to large segmental losses to axial arteries, offer safe and definitive flap coverage to traumatic wounds, improve the array of flap options in this setting, and minimize donor site morbidity. © 2012 Wiley Periodicals, Inc. Microsurgery, 2012.
Addition of sucralose enhances the release of satiety hormones in combination with pea protein
Authors: Geraedts Maartje C. P. , Troost Freddy J. , Saris Wim H. M. 
Published: February 2012

AbstractScope Exposing the intestine to proteins or tastants, particularly sweet, affects satiety hormone release. There are indications that each sweetener has different effects on this release, and that combining sweeteners with other nutrients might exert synergistic effects on hormone release.Methods and results STC‐1 cells were incubated with acesulfame‐K, aspartame, saccharine, sucralose, sucrose, pea, and pea with each sweetener. After a 2‐h incubation period, cholecystokinin(CCK) and glucagon‐like peptide 1 (GLP‐1) concentrations were measured. Using Ussing chamber technology, the mucosal side of human duodenal biopsies was exposed to sucrose, sucralose, pea, and pea with each sweetener. CCK and GLP‐1 levels were measured in basolateral secretions. In STC‐1 cells, exposure to aspartame, sucralose, sucrose, pea, and pea with sucralose increased CCK levels, whereas GLP‐1 levels increased after addition of all test products. Addition of sucrose and sucralose to human duodenal biopsies did not affect CCK and GLP‐1 release; addition of pea stimulated CCK and GLP‐1 secretion.Conclusion Combining pea with sucrose and sucralose induced even higher levels of CCK and GLP‐1. Synchronous addition of pea and sucralose to enteroendocrine cells induced higher levels of CCK and GLP‐1 than addition of each compound alone. This study shows that combinations of dietary compounds synergize to enhance satiety hormone release.
Predictors of care seeking in women with urinary incontinence
Authors: Minassian Vatche A. , Yan Xiaowei , Lichtenfeld Marc J. , Sun Haiyan , Stewart Walter F. 
Published: February 2012

AbstractAimsTo determine predictors of health care utilization in women with urinary incontinence (UI) from the population to specialty care.MethodsThe General Longitudinal Overactive Bladder Evaluation‐UI is a population‐based study on the natural history of UI in women ≥40 years of age. Prevalence of UI was estimated using the Bladder Health Survey (BHS). Survey data were linked with electronic health records (EHRs) to examine factors associated with a clinical UI diagnosis using logistic regression. Risk factors analyzed included: UI symptoms, subtypes, bother, severity, duration, and effect on quality of life, and demographic and other health characteristics. All statistical tests were two‐sided with a P‐value < 0.05 being significant.ResultsThe overall prevalence of any UI based on responses to the BHS was 1,618/4,064 (40%). Of the 1,618 women with UI, there were only 398 (25%) women with EHR (clinical) diagnosis of UI. Women with UI versus those without UI were more likely to be have a BMI >25 kg/m2 (70% vs. 58%), more likely to be parous (91% vs. 87%) and college educated (54% vs. 46%), P < 0.001. After adjusting for confounders in the model, variables significantly associated with clinical UI diagnosis included: older age (OR = 1.96), higher parity (> 1 birth) (OR = 1.76), higher urgency UI (OR = 1.08), adaptive behavior (OR = 1.2), and UI bother scores (OR = 1.01), as well as more frequent outpatient visits (OR = 1.03), P < 0.05.ConclusionsUI is a highly prevalent condition with only a minority of women seeking care. Factors associated with health care utilization include older age, parity (1+), number of doctor visits, urgency UI subtype, UI bother, and impact on behavior. Neurourol. Urodynam. 31:470–474, 2012. © 2012 Wiley Periodicals, Inc.
BUDGETING IN A TIME OF AUSTERITY: THE CASE OF THE ESTONIAN CENTRAL GOVERNMENT
Authors: Jõgiste Kadri , Peda Peeter , Grossi Giuseppe 
Published: February 2012

SUMMARYResulting from the global economic crisis, high budget deficits and debt burden characterise many economies looking for an exit strategy from current fiscal unbalances. The government of Estonia, having pursued a conservative fiscal policy for over a decade, reacted to the economic recession with radical budget adjustments, the latter constituting approximately 9% of gross domestic product in 2009. Consequently, Estonia took its chance and qualified for the euro in 2011. This study examines the behaviour of the Estonian central government and the basis of its budget decisions when planning drastic cost reductions through the theoretical lens of cutback management. The foremost results reveal that the crisis pushed the government to establish a different institutional framework that facilitated fast and effective decision‐making during the budget process. The savings proposals came from the Ministry of Finance; however, running a cash‐basis line‐item budgeting system in practice, the centre possessed only limited performance data for developing the proposals. Consequently, the long‐term impacts of the budget adjustments had not been assessed and are as yet unknown. A further conclusion is that the current budgeting framework should be revised and replaced step by step with a more advanced approach. Copyright © 2012 John Wiley & Sons, Ltd.
Imatinib mesylate causes growth deceleration in pediatric patients with chronic myelogenous leukemia
Authors: Rastogi Maynika V. , Stork Linda , Druker Brian , Blasdel Carolyn , Nguyen Thuan , Boston Bruce A. 
Published: February 2012

AbstractBackgroundImatinib mesylate, a tyrosine kinase inhibitor, is used in the treatment of chronic myelogeneous leukemia (CML). Given its ease of administration and manageable side effects in adults, imatinib mesylate was introduced as therapy for pediatric CML. Recently published case reports describe growth deceleration in children treated with imatinib. This study details the growth phenotype of seven pediatric patients maintained in remission on imatnib mesylate over an extended period of time.ProcedureThis study is a retrospective chart review of pediatric patients with CML at Oregon Health & Science University treated with imatinib. Height, weight, and body mass index (BMI) measurements were collected before and during treatment. Median standard deviation scores (SDS) were analyzed by Wilcoxon Rank‐Sum test and Wilcoxon signed rank cohort analysis.ResultsIndividual patient analysis demonstrated five of seven subjects with a statistically significant decrease in height SDS pre versus during treatment. The whole group analysis showed a trend to significance for difference in median height SDS pre and during treatment (P = 0.078). Bone age was delayed in all four patients in whom bone ages were obtained. IGF‐1, IGFBP‐3, and thyroid levels during treatment were normal. Four patients experienced an improvement in height SDS during puberty. However, three patients approaching near final adult height failed to achieve genetic height potential determined by mid‐parental target height.ConclusionGrowth in children with CML appears to be adversely impacted by imatinib therapy. BMI and IGF‐1/IGFBP‐3 are maintained during treatment, suggesting a direct effect of imatinib on the growth plate. Pediatr Blood Cancer 2012; 59: 840–845. © 2012 Wiley Periodicals, Inc.
Facile synthesis and responsive behavior of PDMS‐b‐PEG diblock copolymer brushes via photoinitiated “thiol‐ene” click reaction
Authors: Yang Muquan , Mao Jun , Nie Wei , Dong Zhixin , Wang Dapeng , Zhao Ziliang , Ji Xiangling 
Published: February 2012

AbstractWe present herein a mild and rapid method to create diblock copolymer brushes on a silicon surface via photoinitiated “thiol‐ene” click reaction. The silicon surface was modified with 3‐mercaptopropyltrimethoxysilane (MPTMS) self‐assembled monolayer. Then, a mixture of divinyl‐terminated polydimethylsiloxane (PDMS) and photoinitiator was spin‐coated on the MPTMS surface and exposed to UV‐light. Thereafter, a mixture of thiol‐terminated polyethylene glycol (PEG) and photoinitiator were spin‐coated on the vinyl‐terminated PDMS‐treated surface, and the sequent photopolymerization was carried out under UV‐irradiation. The MPTMS, PDMS, and PEG layers were carefully identified by X‐ray photoelectron spectroscopy, atomic force microscopy, ellipsometry, and water contact angle measurements. The thickness of the polydimethylsiloxane‐block‐poly(ethylene glycol) (PDMS‐b‐PEG) diblock copolymer brush could be controlled by the irradiation time. The responsive behavior of diblock copolymer brushes treated in different solvents was also discussed. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Novel conjugated copolymers based on dithiafulvalene moiety for bulk heterojunction solar cells
Authors: Chen Yung‐Chung , Hsu Chih‐Yu , Lin Jiann T. 
Published: February 2012

AbstractNew conjugated copolymers, P1‐P3, based on dithiafulvalene‐fused entity and different conjugated segments have been synthesized. Incorporation of electron‐deficient conjugated segments into the conjugated copolymers results in red shifting the absorption band and lowering the hole mobility. Bulk heterojunction solar cells using on these polymers as the donor and [6,6]‐phenyl‐C61‐butyric acid methyl ester (PC61BM) as the acceptor were fabricated by solution process. The cells based on the blend of P1‐P3/PC61BM (1:1, w/w) have power conversion efficiencies (PCEs) ranging from 0.53 to 0.93%. Among these, the cell of P1/PC61BM exhibited the highest open‐circuit voltage at 0.85 V, and the cell of P3/PC61BM exhibited the best PCE at 0.93% with the short‐circuit current (JSC) of 4.88 mA/cm2. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Cyclic polymers: Methods and strategies
Authors: Jia Zhongfan , Monteiro Michael J. 
Published: February 2012

AbstractCyclic polymers have different physical properties compared to their linear counterparts of the same molecular weight. These different properties could have potential impact in the production of new and exciting polymer products. For industry to commercialize such materials, cyclic polymers need to be made on large scales, have controlled molecular weight distributions, and have versatile chemical composition. This highlight article describes many of the synthetic methods and strategies for obtaining highly pure cyclic polymers, and presents kinetic attributes for some of the processes. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Iron‐mediated AGET ATRP of methyl methacrylate using metal wire as reducing agent
Authors: Jiang Hongjuan , Zhang Lifen , Pan Jinlong , Jiang Xiaowu , Cheng Zhenping , Zhu Xiulin 
Published: February 2012

AbstractMethyl methacrylate (MMA) were successfully polymerized by atom transfer radical polymerization with activator generated by electron transfer (AGET ATRP) using copper or iron wire as the reducing agent at 90°C. Well‐controlled polymerizations were demonstrated using an oxidatively stable iron(III) chloride hexahydrate (FeCl3·6H2O) as the catalyst, ethyl 2‐bromoisobutyrate (EBiB) as the initiator, and tetrabutylammonium bromide (TBABr) or triphenylphosphine as the ligand. The polymerization rate was fast and affected by the amount of catalyst and type of reducing agents. For example, the polymerization rate of bulk AGET ATRP with a molar ratio of [MMA]0/[EBiB]0/[FeCl3·6H2O]0/[TBABr]0 = 500/1/0.5/1 using iron wire (the conversion reaches up to 82.2% after 80 min) as the reducing agent was faster than that using copper wire (the conversion reaches up to 86.1% after 3 h). At the same time, the experimental Mn values of the obtained poly(methyl methacrylate) were consistent with the corresponding theoretical ones, and the Mw/Mn values were narrow (∼1.3), showing the typical features of “living”/controlled radical polymerization. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Peptide‐poly(ε‐caprolactone) biohybrids by grafting‐from ring‐opening polymerization: Synthesis, aggregation, and crystalline properties
Authors: Paira Tapas K. , Banerjee Sanjib , Mandal Tarun K. 
Published: February 2012

AbstractWell‐defined peptide‐poly(ε‐caprolactone) (Pep‐PCL) biohybrids were successfully synthesized by grafting‐from ring‐opening polymerization (ROP) of ε‐caprolactone (CL) using designed amine‐terminated sequence‐defined peptides as macroinitiators. MALDI‐TOF‐MS and 1H NMR analyses confirmed the successful attachment of peptide to the PCL chain. The gel permeation chromatography (GPC) measurement showed that the Pep‐PCL biohybrids with controllable molecular weights and low polydispersities (PDI <1.5) were obtained by this approach. The aggregation of Pep‐PCL hybrid molecules in THF solution resulted in the formation of micro/nanospheres as confirmed through FESEM, TEM, and DLS analyses. The circular dichroism study revealed that the secondary structure of peptide moiety was changed in the peptide‐PCL biohybrids. The crystallization and melting behavior of Pep‐PCL hybrids were somewhat changed compared with that of neat PCL of comparable molecular weight as revealed by DSC and XRD measurements. In Pep‐PCL biohybrids, extinction rings were observed in the PCL spherulites, in contrast with the normal spherulite morphology of the neat PCL. There was a substantial decrease (4–5 folds) in the spherulitic growth rate after the incorporation of peptide moiety at the end of PCL chain as measured by polarizing optical microscopy. Pseudomonas lipase catalyzed enzymatic degradation was studied for Pep‐PCL hybrids and neat PCL. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Biodegradable thermoset shape‐memory polymer developed from poly(β‐amino ester) networks
Authors: Lakhera Nishant , Laursen Christopher M. , Safranski David L. , Frick Carl P. 
Published: February 2012

AbstractThe purpose of this study was to develop a degradable thermoset shape‐memory polymer from poly(β‐amino ester) (PBAE) networks. PBAE was chosen to be the crosslinker as it is biodegradable and has been projected as a potential material for biomedical applications. The low glass transition temperature of PBAE was increased to a biomedically relevant range using methyl methacrylate and methyl acrylate as the linear chain builders. The thermo‐mechanical properties of the networks were tailored such that they exhibited onset of glass transition temperature in between the room temperature (22 °C) and the body temperature (37 °C). Free‐strain recovery tests under heating and isothermal conditions were performed to quantify shape‐memory behavior. Testing showed that sampled programmed at 10 °C initiated deformation recovery at a lower temperature and a faster rate as compared to programming at 60 °C. Higher thermal conductivity of water enabled the samples to recover faster in water than in air. Samples with higher PBAE crosslinking densities exhibited higher normalized mass loss under regular and accelerated conditions. The amount of water absorption in the networks also increased with the crosslinker concentration independent of the testing conditions. © 2012 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2012
Psychosexual distress in women with gynecologic cancer: a feasibility study of an online support group
Authors: Classen Catherine C. , Chivers Meredith L. , Urowitz Sara , Barbera Lisa , Wiljer David , O'Rinn Susan , Ferguson Sarah E. 
Published: February 2012

AbstractObjectivesThe psychosexual concerns of gynecologic cancer patients are often unaddressed and there are limited resources available for women to deal with this highly sensitive topic. This feasibility study examines the participation rates and preliminary outcomes for an online support group designed specifically for women who are sexually distressed subsequent to gynecologic cancer treatmentMethodsA 12‐week online intervention was developed to address the psychosexual impact of gynecologic cancer. This intervention included a professionally moderated, asynchronous discussion forum as well as the provision of psycho‐educational materials addressing the psychosexual impact of gynecologic cancer. Each week, a new topic was introduced and relevant material was posted on the website. Women were encouraged to share their experiences related to the topic. Twenty‐seven, sexually distressed, remitted gynecologic cancer patients were randomly assigned to immediate treatment or a waitlist control condition. Participants completed questionnaires at baseline, 4‐month and 8‐month follow‐ups assessing sexual distress as the primary outcome as well as anxiety, depression, and illness intrusiveness.ResultsParticipation rates differed between the two groups, with greater participation occurring in the second group. Exit interviews indicated that the majority of the participants were satisfied with the intervention. Intent‐to‐treat analyses suggest a small effect for reduction in sexual distressConclusionsThis feasibility study suggests that women find this intervention acceptable. Further research is required to determine efficacy. Copyright © 2012 John Wiley & Sons, Ltd.
Non‐geometric fluxes in ten dimensions
Authors: Larfors M. 
Published: February 2012

AbstractIn ten‐ and four‐dimensional supergravities, the descriptions of non‐geometric configurations are different. In the former, non‐geometry arises as naively non‐single valued supergravity fields. In the latter, new terms, coming from “non‐geometric” Q‐ and R‐fluxes, appear in the four‐dimensional potential. We review how these different descriptions can be linked using a ten‐dimensional field redefinition, as proposed by [1]. This change of field basis results in a Q‐flux term in the ten‐dimensional Lagrangian, which can, for certain non‐geometric set‐ups, be dimensionally reduced to its four‐dimensional counterpart. We briefly discuss the global issues of this construction.
The Hirota equation for string theory in AdS5 × S5 from the fusion of line operators
Authors: Benichou R. 
Published: February 2012

AbstractWe present a perturbative derivation of the T‐system that is believed to encode the exact spectrum of planar 𝒩 = 4 SYM. The T‐system is understood as an operator identity between some special line operators, the quantum transfer matrices. By computing the quantum corrections in the process of fusion of transfer matrices, we show that the T‐system holds up to first order in a semi‐classical expansion. This derivation does not rely on any assumption. We also discuss the extension of the proof to other theories, including models describing string theory on various AdS spaces.
Generating higher‐derivative couplings in 𝒩 = 2 supergravity
Authors: Butter D. , Kuzenko S. 
Published: February 2012

AbstractUsing a recently developed off‐shell formulation for general 4D 𝒩 = 2 supergravity‐matter systems, we propose a construction to generate higher derivative couplings. We address here mainly the interactions of tensor and vector multiplets, but the construction is quite general. For a certain subclass of terms, the action is naturally written as an integral over 3/4 of the Grassmann coordinates of superspace.
Topics in 3D 𝒩 = 2 AdS supergravity in superspace
Authors: Tartaglino‐Mazzucchelli G. 
Published: February 2012

AbstractWe review some recent results on the construction in superspace of 3D 𝒩 = 2 AdS supergravities and on the formulation of rigid supersymmetric theories in (1,1) and (2,0) AdS superspaces.
Notes on the overall coefficient of the two‐loop superstring amplitude using pure spinor
Authors: Gomez H. 
Published: February 2012

AbstractUsing the results recently obtained for computing integrals over (non‐minimal) pure spinor superspace, we compute the coefficient of the massless two‐loop four‐point amplitude from first principles. This proceeding is a very short summary on the paper [arXiv:1003.0678 [hep‐th]], which was done with the collaboration of Carlos R. Mafra.
Light‐front higher‐helicity interactions
Authors: Bengtsson A.K.H. 
Published: February 2012

AbstractThe reformulation, using Fock space vertex operators, of the original light‐front cubic interaction terms for higher spin gauge fields is reviewed with comments on quantum higher spin gravity. The formalism is generalized to all orders in the interaction. The ensuing recursive equations for the higher order vertices, if they can be explicitly solved, will encode all interaction data into a denumerable set of rational functions of p+, the overall transverse momentum structure being fixed already at the kinematical level. A more thorough exposition can be found in the archive. This work was presented at the XVII European Workshop on String Theory, Padua, 5–9 September 2011.
Holography and condensed matter
Authors: Benini F. 
Published: February 2012

AbstractThis is a review of recent developments in the application of AdS/CFT methods to some condensed matter problems. In particular we present the holographic description of a local quantum critical state, related to (non)‐Fermi liquids and the strange metal, that appears in large N CFTs with a gravity dual at finite density and zero temperature, and explore its properties by probing it with fermionic operators. Further we discuss possible bosonic and fermionic instabilities, leading to s‐, p‐ or d‐wave holographic superconductors and “electron stars”. Finally we present a realization of local quantum criticality with an impurity problem.
Suppression of defect‐related luminescence in laser‐annealed InGaN epilayers
Authors: Tamulaitis G. , Dobrovolskas D. , Mickevičius J. , Kazlauskienė V. , Miškinis J. , Kuokštis E. , Onufrijevs P. , Medvids A. , Huang J.‐J. , Chen C.‐Y. , Liao C.‐H. , Yang C. C. 
Published: February 2012

AbstractAn In0.21Ga0.79N epilayer has been studied by using spatially‐resolved photoluminescence spectroscopy and Auger electron spectroscopy. The photoluminescence intensity is shown to be distributed highly inhomogeneously, while the epilayer also exhibits strong defect‐related emission. It is shown that laser annealing at high enough power densities causes redistribution of indium atoms and results in suppression of the defect‐related emission. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)