bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metrics from a Congenital Hypothyroidism Screening Program – A Tale of Unmet Challenges
Authors: Kanani Fatima , Kumar Vikram , Mushtaq Mamona , Sameer Dua , Ali Rehan 
Published: February 2025

Background: Congenital hypothyroidism is one of the most common Inherited Metabolic Diseases for which newborn screening is recommended. A wide-scale program for this is lacking in our country.
We undertook a study to retrospectively review our metrics from a regional project for newborn screening of Congenital Hypothyroidism including frequency of elevated neonatal Thyroid Stimulating Hormone (TSH), recall rate, rate of missed testing and turnaround time for results.
Subjects and Method: Retrospective data of neonates born between 13th July 2020 and 10th August 2021 was collected from electronic medical records. Dried blood spot specimens for TSH were collected from the umbilical cords for neonates born vaginally and by heel prick for those born by caesarian section and sent to the designated laboratory. Data was entered on Microsoft Excel and analyzed.
Results: 4037 babies were screened for neonatal TSH, 2149 males and 1888 females. The median (IQR) TSH level was 3.34 (2.09-5.30) µIU/mL. The TSH levels of ≥15 µIU/mL were noted in 95 newborns, out of which 31 newborns had values of ≥ 20 µIU/mL. There was a median (IQR) turnaround time of 14.00 (4.00-55.00) days for initial results accessibility to the clinician. The recall rate was 0.3%. Around 10% of the neonates were not screened and retesting was performed in 12 neonates with high TSH. Only one neonate was identified with persistently raised TSH and suppressed FT4.
Conclusion: Congenital Hypothyroidism was diagnosed in one out of 4037 neonates while 10% were not screened. Recall rate was low, 0.3%. The median turnaround time for reporting was 14 days. Increased awareness, strict monitoring, resource allocation, administrative support and follow-up are required for successful implementation of a CH screening program.
Coccidiosis among goats in Baghdad Province - Iraq
Authors: Ali Faraj Azhar 
Published: February 2025

This study concerned with prevalence of infection of the goats and their kids with coccidia during the period from 1st March 2004 to 30th February 2005. Three hundred fifty two faecal samples were collected from 32 goats. The rate of infections in goats and kids was 47.6%, 61.1% respectively. The peak of infection was in spring and winter, and then the infection declined in hot and dry summer. The rate of infection in females (33.3%) was higher than in males (14.2%). Four species of coccidia were diagnosed Eimeria ahsata, Eimeria faurei, Eimeria pallida, and Eimeria ovinoidalis.
Comparison Of Bacillus anthracis Prepared Used Antigens As ‎Diagnostic kit Of Anthrax In Laboratoy Animals.‎
Authors: A.J.      ‎ Al- Jebouri , G.M.‎ Al- Khatib 
Published: February 2025

This study was concerned on the preparation of several antigens on different
types of culture media like brain heart infusion, tryptic soy agar and broth. A
comparison was carried out among the prepared antigens using skin test in non-
vaccinated guinea pigs which showed negative results. Another trials were conducted using sensitized guinea pigs with live attenuated anthrax vaccine. After three weeks of immunization, skin test was conducted and all antigens revealed positive skin reactions. The highest means were recorded by the dilution 1/40 on the brain heart infusion agar with the mean of erythema of 16.38 mm and a difference of thickness 3.44 mm, while on tryptic soy broth the mean of erythema was 14.14 mm and the difference of thickness was 3.43 mm. The mean of erythema and thickness were 10.21 mm and 2 mm subsequently observed on the dilution 1/40 on tryptic soy agar. The antigen gained from brain heart infusion gave a mean of erythema of 9.5 mm and 3.02 mm thickness. The results mentioned above indicated that the best antigens for the diagnosis and evaluation of anthrax vaccines are the antigen prepared on tryptic soy broth and the two diluted antigens as well.
Digital Transformation of Cooperative Legal Entities in Indonesia
Authors: Sukardi Didi , Hafizd Jefik Zulfikar , Muamar Afif , Hamamah Fatin , Royani Esti , Sobirov Babur 
Published: February 2025

Abstract: This article captures the implementation of cooperative legal entities that are still conventional toward digital transformation, considering significant changes in the world. This study aims to describe how to strengthen the role of cooperatives as a pillar of the Indonesian economy, the legal basis for digital transformation, and the digital transformation of legal entity cooperatives in Indonesia. The findings show that transforming the cooperative business model into a digital basis is necessary. Cooperatives can obtain a vast market share by using tools such as website companies, social media, marketplace, and paid online advertising. The legal basis for business transformation from conventional to electronic-based models already exists. Cooperative legal entities can conduct business activities by utilizing digital technology for various activities such as administration, marketing via internet media, advertising using third parties such as Facebook Ads or Google Ads, selling products through online stores, analyzing business trends in the community, building relationships with more parties through social media, member meetings using video call applications, and many more that can be utilized. With the G20 forum, opportunities to expand business to various countries need to be used optimally by cooperatives in Indonesia.

Keywords: Digital, Legal Entities, and Cooperatives.
A life dedicated to surgery: Serhii Tymofieiev’s contribution to medicine and education
Authors: Tsiura Y. P. , Kryvopustov M. S. 
Published: February 2025

Serhii Lukianovych Tymofieiev (1875—1943) was a renowned physician, surgeon, scientist, and teacher in the history of Ukrainian medicine. Continuous education and practice shaped his professional career, which began in the Kherson province. Tymofieiev became a Doctor of Medical Sciences after defending his dissertation on the pathogenesis of renal edema. His contribution covers several medical fields, including orthopedics, traumatology, urology, and military surgery. Serhii Lukianovych founded the Department of Traumatology and Orthopedics at the Kyiv Medical Institute, which became the basis for the development of modern Ukrainian orthopedics. He developed innovative approaches to the treatment of injuries, reconstructive surgery, and the training of future doctors. During World War I, Tymofieiev headed the surgical department of the Kyiv Military Hospital, where he treated gunshot wounds. His pedagogical activity was focused on improving the teaching of military field surgery, a topic that is particularly relevant during times of military conflicts. Tymofieiev not only worked tirelessly but also educated a generation of doctors who continued his legacy. Having written more than 90 scientific works, he became one of the founders of Ukrainian surgery and medical education. His life path is an example of high professionalism, extensive scientific knowledge, and commitment to the medical profession. Tymofieiev made a significant contribution to the history of medicine, and his legacy continues to inspire modern doctors.
26-Year perspective on stapled hemorrhoidopexy – insights into managing severe complications. Two case reports and literature review
Authors: Prokopchuk O. , Fuchs F. , Nedic D. , Quaiser D. , Novotny H. F. G. , Friess H. , Bachmann J. , Spelsberg F. 
Published: February 2025

Stapled Hemorrhoidopexy, first introduced by Longo in 1998, has become a widely adopted surgical method for treating hemorrhoidal disease. This innovative procedure gained popularity due to reduced postoperative pain, shorter hospital stays, and faster recovery. However, it is not without risk and is associated with rare but severe complications that can significantly affect patient outcomes. This study describes two illustrative clinical cases of such complications. The first case involves a 41‑year‑old male patient who developed a perirectal hematoma accompanied by acute abdominal bleeding caused by mesenteric vessel rupture at the rectosigmoid junction. Urgent surgical intervention and intensive postoperative care were required. The second case concerns a 49‑year‑old female patient who experienced anal stenosis and subsequent fecal incontinence, necessitating both surgical correction and prolonged rehabilitative therapy to restore bowel function and improve quality of life. These cases emphasize the critical importance of early recognition and effective management of complications associated with stapled hemorrhoidopexy. They also highlight the necessity of a multidisciplinary approach involving colorectal surgeons, general surgeons, and gastroenterologists to optimize patient care.A comprehensive literature review identifies key risk factors for complications, including patient comorbidities, technical nuances of the procedure, and the careful selection of candidates. Best practices for preventing and managing complications are also discussed, focusing on surgical technique refinement, thorough preoperative evaluation, and enhanced staff training. These insights aim to equip clinicians with essential knowledge to minimize risks, enhance patient safety, and maintain the advantages of this innovative method.
ІСТОРИЗМ В АРХІТЕКТУРНОМУ ОБРАЗІ БУДІВЕЛЬ ПОЧАТКУ ХХІ ст. (НА ПРИКЛАДІ МІСТА РІВНОГО)
Authors: Ісупова М. І. 
Published: February 2025

Статтю присвячено дослідженню історизму в архітектурному образі будівель 2000–2020-х рр. м. Рівного. Історизм являє собою стійку архітектурну тенденцію впродовж років незалежності України. У м. Рівному значна частина новобудов містить стилістичні елементи історичних стилів. Типологія архітектури історизму 2000–2020-х рр. представлена офісними центрами, будівлями комерційного призначення, готелями, багатоквартирними житловими будинками. Також характерним явищем є зміна стилістичного рішення фасадів існуючих будівель при їх реконструкції шляхом застосування архітектурних деталей історичних стилів.Часто через перенасичення фасадів деталями будівлі 2000–2020-х рр. стилістично являють собою архітектуру кітчу, проте розмаїття проявів історизму створює можливість втілення принципу контекстуалізму й врахування специфіки існуючого архітектурного середовища при спорудженні нових будівель, що особливо актуально для історичного центру міста.
Afinidad a la diversidad en estudiantes universitarios: un estudio comparativo
Authors: Morales-Álvarez Agustín , García-Vázquez Fernanda Inéz , Gálvez-Díaz Mayra Karina 
Published: February 2025

La afinidad a la diversidad es una variable que ha tomado relevancia en la investigación; sin embargo, en población universitaria aún es incipiente. El objetivo del presente estudio fue identificar los niveles de afinidad a la diversidad en estudiantes universitarios, asimismo determinar las diferencias en los niveles de afinidad a la diversidad según el sexo y el nivel de violencia en la región de residencia. Se llevó a cabo un estudio cuantitativo, transversal, descriptivo y comparativo. La muestra del estudio fue de 402 estudiantes universitarios del noroeste de México (58% del sexo femenino) con edades entre los 18 y los 52 años (Medad = 21.20, DE = 4.75). Los resultados sugieren que los estudiantes tienen niveles moderados-altos de afinidad hacia la diversidad, además se encontró que las mujeres tienen puntajes significativamente más altos en la afinidad a la diversidad que sus pares hombres, aunque no se encontraron diferencias estadísticamente significativas según el nivel de violencia en la región de residencia. Se concluye que los estudiantes universitarios cuentan con una predisposición favorable hacia las personas con antecedentes socioculturales, económicos y sexuales distintos a los suyos, lo cual puede favorecer la integración de las minorías sociales.
Impact of GLP-1 Receptor Agonists on Body Weight and Cardiovascular Outcomes: A Systematic Review
Authors: Mutairi Ahmed Al 
Published: February 2025

The effects of glucagon-like peptide-1 (GLP-1) receptor agonists on cardiovascular outcomes and body weight have garnered considerable clinical attention, especially in the context of addressing type 2 diabetes (T2D) and its related comorbidities. The purpose of this systematic review was to assess the safety and effectiveness of several GLP-1 receptor agonists in relation to weight loss and cardiovascular outcomes. Using a combination of keywords, MeSH terms, and Boolean operators, the search process was carried out in PubMed, Embase, Scopus, Web of Science, Cochrane Library, and ClinicalTrials.gov. The GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) method was used to gauge the degree of certainty in the evidence, and the Cochrane’s RoB 2.0 tool was used to assess the risk of bias in the included studies. To reduce bias and mistakes, each paper was examined independently by two reviewers. The review comprised 21 studies in total. Weight, BMI, WC, SBP, TC, and TG were all considerably decreased by ligarglutide 3.0 mg in both obese/overweight people without T2D and those who had the disease. In a variety of groups, semaglutide 2.4 mg showed strong effectiveness in lowering weight, BMI, WC, SBP, and improving TG ratios. When paired with rigorous behavioural therapy, additional advantages were seen. Weight and metabolic indices were reduced in a dosedependent manner by tirzepatide. Liraglutide, semaglutide, albiglutide, dulaglutide, and efpeglenatide showed significant reductions in major adverse cardiovascular events, according to cardiovascular outcome-focused trials; lixisenatide and exenatide did not demonstrate significant cardiovascular benefits. Comparative investigations showed that exenatide QWS-AI provided better glycaemic control, while liraglutide and combination therapy significantly improved MetS-Z and android fat percentage. GLP-1 receptor agonists have often shown to have a major positive impact on improving metabolism, lowering cardiovascular risk, and losing weight. Behavioural treatments, the presence of T2D, and the particular GLP-1 agonist utilised all had an impact on the efficacy. These results provide credence to the use of GLP-1 receptor agonists as a helpful therapeutic option for patients with T2D and obesity who wish to manage their weight and cardiovascular health.
BJMS, Volume: 24. Supplementary Issue 2025, Page : 45-58
ARTDET: la inteligencia artificial facilita la detección de daños y antiguas intervenciones en pinturas sobre lienzo
Authors: Del Castillo de la Fuente José Manuel , García-Moreno Francisco M. , Hurtado-Torres María Visitación , Cortés Alcaraz Jesús , Rodríguez-Simón Luis Rodrigo 
Published: February 2025

Desde la Universidad de Granada, un grupo de investigadores formado por doctores en Ingeniería Informática y restauradores, han desarrollado un software capaz de detectar daños y antiguas intervenciones en pinturas sobre lienzo para crear mapas de daños automáticamente, gracias a la Inteligencia Artificial. Este programa, supone un avance significativo en la implementación de nuevas tecnologías en el campo de la restauración y los procesos de documentación; logrando optimizar notablemente el tiempo de trabajo. La propuesta destaca por su innovación en la incorporación de la tecnología Machine Learning a los procesos de documentación; donde no solo se potencia la precisión de los resultados, sino que además facilita la elaboración de los mapas.
Un acercamiento al Certamen de Investigación Cultural Publio Hurtado de la Asociación Adaegina Amigos del Museo de Cáceres
Authors: Grisalvo Rosado Manuel 
Published: February 2025

El Certamen de Investigación Cultural Publio Hurtado pretende promover los trabajos de investigación sobre el patrimonio etnológico y la antropología cultural de Extremadura. Su denominación quiere ser un homenaje al polígrafo extremeño autor del trabajo Supersticiones extremeñas y estrechamente vinculado a la creación del Museo de Cáceres a través de la Comisión de Monumentos Históricos y Artísticos de Cáceres, de la que formó parte entre 1897 y el momento de su fallecimiento en 1929, siendo su presidente los últimos diez años. Actualmente acaba de finalizar el plazo de presentación de trabajos para la VIII edición del Certamen.
PKM SOSIALISASI PERAN FISIOTERAP DAN DOKTER DI APLIKASI FISDOK DI DESA BANJARSARI KECAMATAN GAJAH KABUPATEN DEMAK
Authors: Sugiharto Sigit , - Kuswardani 
Published: February 2025

Kegiatan pengabdian masyarakat ini merupakan upaya peningkatan pengetahuan dan pemahaman kader posyandu di Desa Banjarsari tentang layanan fisioterapi pada aplikasi FisDok hasil karya mahasiswa Universitas Widya Husada Semarang Program Studi Diploma Tiga Fisioterapi. Fokus dari pelaksanaan PKM ini adalah upaya sosialisasi tentang peran fisioterapi dan dokter pada aplikasi FisDok. Target khusus dari kegiatan PKM ini adalah mengajarkan sistem pendampingan pada para ibu kader di desa Banjarsari Kecamatan Gajah Kabupaten Demak tentang pentingnya peran fisioterapi dan dokter pada aplikasi FisDok. Metode kegiatan pengabdian ini dilakukan dengan cara memberikan pendampingan mulai dari melakukan penyuluhan dan diskusi, sosialisasi dan aplikasi bentuk pelyanan fisioterapi dan dokter pada para kader di Desa Banjrsari. Anggaran dan jadwal pelaksanaan pengabdian masyarakat yang diajukan sudah sangat relevan atau sesuai dengan kegiatan yang akan dilaksanakan. Rencana kegiatan program PKM ini adalah a) Pra survei lapangan, b) Persiapan alat dan bahan pelatihan, c) Persiapan metode pelatiahan, d) Sosialisasi dan pelatihan senam hamil, e) Pendampingan, f) evaluasi, g) Pembuatan program keberlanjutan. Berdasarkan hasil sosialisasi dan pelatihan didapatkan hasil yang signifikan yaitu para ibu kader dapat memanfaatkan pelayanan kesehatan yang ada di aplikasi FisDok dan menyebarluaskan ke masyarakat desa Banjarsari.
Fluid-structure interaction analysis for abdominal aortic aneurysms: the role of multi-layered tissue architecture and intraluminal thrombus
Authors: Yue Xinhai , Huang Jiayi , Liu Ju 
Published: February 2025

IntroductionAbdominal aortic aneurysm (AAA) is a life-threatening disease marked by localized dilatations of the infrarenal aortic wall. While clinical guidelines often use the aneurysm diameter as an indicator for surgical intervention, this metric alone may not reliably predict rupture risks, underscoring the need for detailed biomechanical analyses to improve risk assessments.MethodsWe investigate the effects of the multi-layered tissue architecture and the intraluminal thrombus (ILT) on the wall stress distribution of AAA. Using fluid-structure interaction, we analyze the biomechanical responses of fusiform and saccular AAAs under three conditions: without ILT, with ILT but no tissue degradation, and with both ILT and tissue degradation.ResultsThe findings show that the media is the primary load-bearing layer, and the multi-layered model yields a more accurate stress profile than the single-layered tissue model. The ILT substantially reduces overall stress levels in the covered tissue, although its impact on the location of peak stress varies across different scenarios. Media degradation increases the stress in the intima and adventitia, but the cushioning effect of ILT largely mitigates this impact.DiscussionThe results underscore the importance of incorporating the multi-layered tissue architecture and ILT in patient-specific analyses of AAA. These factors may improve the predictive capabilities of biomechanical assessments for rupture risk.
Enhancing privacy and traceability of public health insurance claim system using blockchain technology
Authors: Alamsyah Andry , Setiawan I. Putu Sadhu 
Published: February 2025

IntroductionThe insurance industry has evolved into a global multi-billion-dollar sector, with health insurance gaining prominence due to escalating healthcare costs. This rapid expansion brings heightened risks, including data breaches, fraud, and difficulties in safeguarding sensitive policyholder information. Indonesia’s National Health Insurance (NHI)—one of the largest national insurance programs worldwide—covers over 200 million citizens, aiming to provide universal healthcare. However, this extensive coverage raises substantial concerns about data privacy and traceability, particularly during the claim process, as policyholders currently have limited control over and insight into how their data is accessed and used.MethodsTo address these challenges, we propose a blockchain-based model designed to enhance policyholders’ private control over data access and improve traceability throughout the NHI claim process. Our approach employs three complementary architectures—functional, logical, and physical—to guide system implementation. The functional architecture is illustrated via a use case diagram that outlines the roles and actions of each participant. The logical architecture employs Business Process Model and Notation (BPMN) diagrams to depict the revised process flow and data movement, while also incorporating a layered design concept. The physical data architecture provides a class diagram detailing data structures and actor relationships. A proof-of-concept prototype was developed to demonstrate the core functionalities of the new system.ResultsBy integrating blockchain technology, our prototype ensures authorized access, bolsters data privacy, and maintains data integrity in the NHI claim workflow. The system’s layered design and use of smart contracts guarantee transparent, tamper-proof record-keeping, while parallelized processes in the logical architecture streamline claims handling. Initial tests of the prototype confirm the feasibility and robustness of the proposed solution, illustrating how blockchain can facilitate traceability and preserve confidentiality.DiscussionThe blockchain-based design addresses pressing concerns surrounding data security and accountability in large-scale health insurance systems. It allows policyholders to monitor and control their personal information, reducing the likelihood of unauthorized use. Furthermore, the transparent and immutable ledger enables stakeholders to verify data provenance and transactions, enhancing trust. Future work will focus on scalability, regulatory compliance, and integration with existing healthcare IT infrastructures to fully realize the benefits of blockchain in national health insurance programs.