bluuebunny/crossref_metadata_2025_split huggingface dataset:
Splenic flexure mobilization in left‐sided colonic and rectal resections: A meta‐analysis and meta‐regression of factors associated with anastomotic leak and complications
Authors: Emile Sameh Hany , Dourado Justin , Rogers Peter , Horesh Nir , Garoufalia Zoe , Gefen Rachel , Wexner Steven D. 
Published: May 2024

AbstractAimSplenic flexure mobilization (SFM) is commonly performed during left‐sided colon and rectal resections. The aim of the present systematic review was to assess the outcomes of SFM in left‐sided colon and rectal resections and the risk factors for complications and anastomotic leak (AL).MethodThis study was a PRISMA‐compliant systematic review. PubMed, Scopus and Web of Science were searched for studies that assessed the outcomes of sigmoid and rectal resections with or without SFM. The primary outcomes were AL and total complications, and the secondary outcomes were individual complications, operating time, conversion to open surgery, length of hospital stay (LOS) and pathological and oncological outcomes.ResultsNineteen studies including data on 81 116 patients (49.1% male) were reviewed. SFM was undertaken in 40.7% of patients. SFM was associated with a longer operating time (weighted mean difference 24.50, 95% CI 14.47–34.52, p < 0.0001) and higher odds of AL (OR 1.19, 95% CI 1.06–1.33, p = 0.002). Both groups had similar odds of total complications, splenic injury, anastomotic stricture, conversion to open surgery, (LOS), local recurrence, and overall survival. A secondary analysis of rectal cancer cases only showed similar outcomes for SFM and the control group.ConclusionsSFM was associated with a longer operating time and higher odds of AL, yet a similar likelihood of total complications, splenic injury, anastomotic stricture, conversion to open surgery, LOS, local recurrence, and overall survival. These conclusions must be cautiously interpreted considering the numerous study limitations. SFM may have only been selectively undertaken in cases in which anastomotic tension was suspected. Therefore, the suboptimal anastomoses may have been the reason for SFM rather than the SFM being causative of the anastomotic insufficiencies.
Identification and analysis of prognostic immune cell homeostasis characteristics in lung adenocarcinoma
Authors: Sun Yidan , Ma Qianqian , Chen Yixun , Liao Dongying , Kong Fanming 
Published: May 2024

AbstractBackgroundLung adenocarcinoma (LUAD) is one of the most invasive malignant tumor of the respiratory system. It is also the common pathological type leading to the death of LUAD. Maintaining the homeostasis of immune cells is an important way for anti‐tumor immunotherapy. However, the biological significance of maintaining immune homeostasis and immune therapeutic effect has not been well studied.MethodsWe constructed a diagnostic and prognostic model for LUAD based on B and T cells homeostasis‐related genes. Minimum absolute contraction and selection operator (LASSO) analysis and multivariate Cox regression are used to identify the prognostic gene signatures. Based on the overall survival time and survival status of LUAD patients, a 10‐gene prognostic model composed of ABL1, BAK1, IKBKB, PPP2R3C, CCNB2, CORO1A, FADD, P2RX7, TNFSF14, and ZC3H8 was subsequently identified as prognostic markers from The Cancer Genome Atlas (TCGA)‐LUAD to develop a prognostic signature. This study constructed a gene prognosis model based on gene expression profiles and corresponding survival information through survival analysis, as well as 1‐year, 3‐year, and 5‐year ROC curve analysis. Enrichment analysis attempted to reveal the potential mechanism of action and molecular pathway of prognostic genes. The CIBERSORT algorithm calculated the infiltration degree of 22 immune cells in each sample and compared the difference of immune cell infiltration between high‐risk group and low‐risk group. At the cellular level, PCR and CKK8 experiments were used to verify the differences in the expression of the constructed 10‐gene model and its effects on cell viability, respectively. The experimental results supported the significant biological significance and potential application value of the molecular model in the prognosis of lung cancer. Enrichment analyses showed that these genes were mainly related to lymphocyte homeostasis.ConclusionWe identified a novel immune cell homeostasis prognostic signature. Targeting these immune cell homeostasis prognostic genes may be an alternative for LUAD treatment. The reliability of the prediction model was confirmed at bioinformatics level, cellular level, and gene level.
Dispersal restriction and facilitation in species with differing tolerance to development: A landscape genetics study of native and introduced lizards
Authors: Phillips Payton M. , Langhans Kelley E. , Helmus Matthew R. , Jesse Wendy A. M. , Surget‐Groba Yann , Behm Jocelyn E. 
Published: May 2024

AbstractAimThe development of natural habitats into urban land uses has greatly accelerated in the recent past due to human activities. This habitat development disrupts species' natural dispersal processes and can lead to both direct and indirect impacts on dispersal. Whether human activities result in restricted or facilitated dispersal may depend on a species' development tolerance; however, this premise has not been tested. We examined the impact of urbanization and road networks on the dispersal of three lizard species in the context of their development tolerance.LocationCuraçao.MethodsTo quantify species' development tolerance, we modelled three lizard species abundances at sites based on surrounding landscape development. Using microsatellite genotypes, we conducted individual‐based resistance surface analyses and modelled the effect of habitat development on genetic admixture to assess indirect dispersal restriction and facilitation. We explored direct facilitation of dispersal using network analysis of mitochondrial haplotypes.ResultsPhyllodactylus martini, a native gecko species, was the least tolerant of development and experienced indirect dispersal restriction due to roads, according to resistance surface analyses. Anolis lineatus, a native anole species, exhibited a neutral relationship with development. Resistance surfaces and Structure analyses showed that A. lineatus faced indirect dispersal restrictions from roads and developed areas, while mitochondrial haplotype networks suggested they benefited from occasional human‐facilitated long‐distance dispersal events. Hemidactylus mabouia, an introduced gecko species, was the most tolerant of development, and experienced no dispersal restriction, but mitochondrial haplotypes suggest direct long‐distance dispersal facilitation.Main ConclusionsOur findings highlight development tolerance as a key predictor of dispersal impact for these species and future work should test whether these patterns are upheld in other systems. Understanding how human activities affect species' dispersal will aid in managing introduced species while promoting connectivity for native species navigating dispersal challenges in dynamic landscapes.
Power dynamics in couple relationships: A review and applications for systemic family therapists
Authors: Young Bonnie , Seedall Ryan B. 
Published: May 2024

AbstractPower dynamics, generally defined as the patterns of partners enacting or resisting influence, are inherent in all relationships. Power structures and processes play a role in people's perceptions of themselves and others, their feelings and emotions, and both their implicit and explicit behaviors. As such, understanding power dynamics is crucial for fully conceptualizing and intervening within relationships. Although power was not always given high priority in many of the early systemic family therapy models, that has changed over the years, with scholars working to address how power is manifested in relationships, how power imbalances affect relationships, and how power can be addressed more explicitly in treatment. Nonetheless, there is much additional work needed to ensure that systemic therapists have an appropriate depth of understanding regarding power dynamics to fully recognize their manifestations in relationships and then intervene appropriately. To help in these efforts, this paper aims to synthesize relational power research into a more complete description of what power is and how it is enacted in couple relationships. To do this, we introduce relevant perspectives of power not fully integrated with family therapy theories. Overall, we provide a brief history of power‐oriented research in the fields of family therapy, outline couple research regarding the sources of power that can inform therapeutic case conceptualizations and interventions, describe how power is addressed in specific couple therapy models, and highlight some important clinical applications that can help systemic therapists more fully address power.
Development and validation of the Multidimensional Mindset Scale: Growth and fixed mindsets
Authors: Ortiz Alvarado Nancy , Quintanilla Domínguez Claudia , Ayala Gaytan Edgardo , Del Castillo de la Fuente Ernesto 
Published: May 2024

AbstractEvidence suggests that fixed and growth mindsets shape human behavior (Rucker & Galinsky, Journal of Consumer Psychology, 2016;26(1):161–164); however, empirical research on mindsets is highly sensitive in terms of how they are measured. This article addresses specific limitations in measuring growth and fixed mindsets using existing scales, especially Dweck's (Self‐theories: Their role in motivation, personality, and development, 2000) scale, which is the most recognized and commonly used instrument in this area. The main contribution of the article is that it develops an alternative scale that addresses these potential limitations; specifically, the proposed scale (1) measures the fixed and growth mindsets as independent constructs (note that We refer to “independence” among constructs (fixed and growth), considering that they are not just two opposite constructs of the same continuum, but different constructs. Thus, we included items for each one to capture the properties of each construct while avoiding the use of the same items in reverse coding), (2) does not use reverse coding, and (3) comprises four dimensions including important variables that should be considered when measuring mindsets: intelligence beliefs, practice and effort, challenges, and multiple intelligence. To this end, we employed a multi‐method approach by combining qualitative research with the exploratory and confirmatory factor analysis of a survey database to arrive at a 25‐item scale of growth and fixed mindsets. The scale, denoted as the Multidimensional Mindset Scale (MUMIS), satisfies reliability, convergent, divergent, and nomological validity tests. MUMIS opens new avenues to explore the understanding of the effects of specific intelligence beliefs, practice and effort, challenges, and multiple intelligence in fields like consumer behavior, education, psychology, and well‐being.
Effects of different extraction methods on the structure and function of blackberry seed polysaccharides
Authors: Yang Mo , Gong Hao , Jiang Cheng‐gong , He Yu , Wang Shuai , Zheng Yi , Hou Jin‐hui , Wang Wei‐dong 
Published: May 2024

SummaryThe different extraction methods including hot‐water extraction, ultrasound‐assisted extraction, and microwave‐assisted extraction, enzyme‐assisted extraction, ultrasound and microwave‐assisted extraction, and ultrasound and enzyme‐assisted extraction (UEE) methods were carried out to extract blackberry seed polysaccharides (BSPs). The extraction yield, structure, antioxidant capacity, and glucometabolic enzyme inhibition activities of BSPs were determined in this work. Extraction methods have no influence on the monosaccharide composition of BSPs but affected the molar ratio of monosaccharides. Fourier transform infrared spectroscopy and X‐ray diffraction results showed that the extraction method cannot effect on the functional groups and crystal forms of BSPs. The findings also revealed that UEE led to the highest BSP extraction yield (4.56%), highest antioxidant capacities, and highest α‐amylase (48.49%) and α‐glucosidase (67.33%) inhibitory rates, which may because of the dispersed molecular weight distribution and loose microstructure of BSPs. These results suggest that UEE may be used in the industry to obtain BSPs with high functional activities.
Quality enhancement of sweet potato puree oat mixed‐grain noodles based on curdlan: recommended addition level and mechanism
Authors: Wei Xinyu , Ren Guangyue , Duan Xu , Li Linlin , Cao Weiwei , Chen Junliang , Sun Xiaofei , Zhao Linlin , Liu Wenchao 
Published: May 2024

SummaryThe inherent poor cooking quality and poor texture of mixed‐grain pasta limit consumer acceptance. This study systematically investigated the effect of curdlan in the processing of sweet potato puree oat mixed‐grain noodles, and comprehensively analysed a number of key indicators such as cooking characteristics, moisture state, texture properties, microstructure, starch crystallinity characteristics, short‐range ordered structure and thermal properties. At the production practice level, the study clearly indicated that the 0.6% curdlan addition ratio was the best solution in sweet potato puree oat mixed‐grain noodles processing. This finding not only significantly reduces the fracture rate, water absorption rate and cooking loss rate during the cooking process, but also significantly improves the quality and yield of the product, and brings significant improvement in the taste and texture of the noodles, which is of great significance for industrial production. In the microstructural and molecular studies, we revealed how curdlan could enhance the structural stability and mechanical strength of noodles by promoting the uniform distribution of starch granules in the gluten protein network. Further, through X‐ray diffraction, ordered structure and thermal property analyses, we have found that colchicine can effectively regulate the interactions of hydrogen bonding between starch and the content of straight‐chain and branched‐chain starch, which significantly reduces the crystallinity, ordered short‐chain structure and enthalpy of pasting of starch in the pasta. These in‐depth research results not only help us to understand more comprehensively the formation mechanism of the modification of pasta quality by curdlan, but also provide a solid theoretical foundation and practical guidance for the improvement of pasta quality in mixed grains.
Elderberry pomace for food/nutraceutical product development: impact of drying methods and simulated in vitro gastrointestinal digestion on phenolic profile and bioaccessibility
Authors: Gomez Mattson Milagros , Corfield Rocío , Schebor Carolina , Salvatori Daniela 
Published: May 2024

SummaryThe aim of this work was to develop ingredients from elderberry pomace (EP) analysing the effect of different drying methods (conventional air‐drying (C), freeze‐drying (F), and fluidised‐bed drying (FB)) on phenolic compounds retention and their bioaccessibility. The dry pomaces were chemically characterised before and after an in vitro gastrointestinal digestion (GID). Cianidin‐3‐glucoside and rutin were the main phenolic compounds determined by HPLC‐DAD. After GID, phenolic content and antioxidant capacity were drastically reduced regardless of the drying process. Freeze‐drying better preserved the total polyphenol and monomeric anthocyanin content, and the antioxidant capacity, however, EP‐C and EP‐FB presented more bioaccessible antioxidant compounds than EP‐F. Fluidised‐bed drying generated, in a shorter drying time, a more bioaccessible granular product (EP‐FB), that could be used directly in ready‐to‐eat foods. EP‐C and EP‐F products could be used as functional foods or nutraceutical ingredients. Also, the obtained elderberry products were not cytotoxic against the Caco‐2 cell line.
The feasibility of a psychological first aid intervention as a supportive tactic for feelings of psychological distress and mental health recovery outcomes among earthquake survivors in Northern Syria
Authors: Khedr Mahmoud Abdelwahab , Al‐Ahmed Nassan Ali , Mattar Fayez Kheled , Alshammari Mukhlid , Ali Eman Abdeen 
Published: May 2024

AbstractAimThis study aimed to investigate the feasibility of implementing a psychological first aid intervention for psychological distress, resilience capacity, quality and meaning of life among survivors affected by earthquake adversity in Northern Syria.MethodsA quasi‐experimental, pre‐posttest, two‐group research design was utilized. A convenience sample of 95 survivors (46 in the study group and 49 in the control group) was recruited for the psychological First Aid intervention at a 1:1 ratio. The psychological first aid intervention was delivered in 10 sessions, twice weekly, followed by 3‐month follow‐up.ResultsA statistically significant improvement in the mean scores of resilience capacity, quality and meaning of life among survivors, along with a significant reduction in psychological distress, was registered among the study group compared with the control group.ConclusionOur work verified the suitability of implementing psychological first aid following the catastrophic temblors which struck Northern Syria. Given that the psychological first aid intervention is grounded in psychological safety, cognitive reframing, mobilization of social support and installation of hope, the feasibility of its path following public health emergency, traumatic events or even a personal crisis can be favourable.
Increasing precision during neuromodulator injections for frontal rhytids—Using ultrasound imaging to identify the line of convergence
Authors: Meneses Claudia C. B. , Freitas Silvio , Knoedler Leonard , Knoedler Samuel , Davidovic Kristina , Bravo Carlos , Pappas AmberLeigh , Biesman Brian S. , Alfertshofer Michael , Cotofana Sebastian 
Published: May 2024

AbstractBackgroundRecent research introduced the concept of the “line of convergence” as a guide for injectors to enhance precision and avoid complications when treating the frontalis muscle with toxins. However, currently, no pre‐injection ultrasound scanning is employed to increase precision and reduce adverse events when searching for the line of convergence.ObjectiveTo explore the feasibility and practicality of implementing pre‐injection ultrasound scanning into aesthetic neuromodulator treatments of the forehead.MethodsThe sample of this study consisted of n = 55 volunteers (42 females and 13 males), with a mean age of 42.24 (10.3) years and a mean BMI of 25.07 (4.0) kg/m2. High‐frequency ultrasound imaging was utilized to measure the thickness, length, and contractility of the frontal soft tissue and to determine the precise location of the line of convergence during maximal frontalis muscle contraction.ResultsThe results revealed that the line of convergence was located at 58.43% (8.7) of the total forehead height above the superior border of the eyebrow cilia without a statistically significant difference between sex, age, or BMI. With frontalis muscle contraction, the forehead shortens in males by 25.90% (6.5), whereas in females it shortens only by 21.74% (5.1), with p < 0.001 for sex differences.ConclusionThis study demonstrated the feasibility and practicality of pre‐injection ultrasound scanning for facial aesthetic neuromodulator treatments. Knowing the location of the line of convergence, injectors can determine precisely and on an individual basis where to administer the neuromodulator deep or superficial or when the injection location is at risk to cause eyebrow ptosis.
Nurses' knowledge, attitudes and practices regarding the application of the injury severity score in emergency departments: A cross‐sectional multicentre study
Authors: Wu Hui , Ma Xiaoyan , Hao Yaru , Ji Li , Zhu Wei , Mu Wenjing , Guo Yue , Fan Luo 
Published: May 2024

AbstractAims and ObjectivesTo investigate knowledge, attitudes, and practices regarding the application of the Injury Severity Score (ISS) among emergency department nurses in China and the factors influencing these variables.BackgroundISS is the first trauma scoring method to be developed and the most widely used in clinical practice. The correct application of the ISS by emergency department nurses plays an important role in assisting in the diagnosis and treatment of trauma patients, and it is crucial to understand nurses' knowledge, attitudes and practices.DesignA cross‐sectional multicentre study.MethodsNurses from the emergency departments of 25 grade II and grade III hospitals in Gansu Province, China participated in this study. Data was collected online using a self‐administered questionnaire. Student's t‐test or analysis of variance was performed to compare the differences between the groups. Multiple logistic regression analysis identified factors influencing nurses' knowledge, attitudes and practices regarding applying ISS. A STROBE checklist was used to report findings.ResultsAmong 459 nurses, a good level of attitude and passing levels of knowledge and practice regarding applying the ISS were revealed. Nurses in higher hospital grades, who had been exposed to ISS and received training had higher levels of knowledge and practices. Previous exposure to the ISS and training related to it were factors that influenced nurses' attitudes.ConclusionsChinese emergency department nurses' knowledge, attitudes and practices of applying the ISS still need to be improved. Hospitals and nursing managers should provide training opportunities for nurses about ISS knowledge and practices, while grade II hospitals should pay more attention to training and continuing education in this area.Relevance to Clinical PracticeIn hospitals, nursing managers may benefit from enhancing related education and training to promote the emergency department nurses' knowledge and practice of the ISS, by developing specific curricula and providing continuing education and training opportunities, while grade II hospitals should pay more attention to training and continuing education in this area.No patient or Public ContributionsThis study focused on emergency department nurses' knowledge, attitudes, and practices regarding the application of the ISS. The research questions and design were derived from clinical nursing practice, literature review, and expert panel review, and patients or the public are temporarily not involved.
Toxoplasma gondii and Neospora caninum infection in epileptic dogs
Authors: Morganti G. , Rigamonti G. , Marchesi M. C. , Maggi G. , Angeli G. , Moretta I. , Brustenga L. , Diaferia M. , Veronesi F. 
Published: May 2024

ObjectivesStudies in humans have demonstrated the role of Toxoplasma gondii, a protozoan parasite, in epileptic seizures. This study aimed to investigate the serological correlation between T. gondii and N. caninum and epilepsy in dogs.Materials and MethodsThe medical record database of the Veterinary Teaching Hospital, University of Perugia, was searched for dogs serologically tested by IFAT for T. gondii and N. caninum and following specific inclusion criteria. Dogs were stratified by having a clinical diagnosis of epilepsy or suffering different conditions.ResultsOne‐hundred and twenty‐eight dogs were included, 64 with epilepsy and 64 without clinical signs of epilepsy. Seventeen of the 64 epileptic dogs (26.6%; 95% CI: 15.7% to 37.4%) and twenty‐one of the 64 non‐epileptic dogs (32.8%; 95% CI: 21.3% to 44.3%) tested positive for T. gondii. Eight of the epileptic dogs (12.5%; 95% CI: 4.4% to 20.6%) and three of the non‐epileptic dogs (4.7%; 95% CI: 0% to 9.9%) tested positive for N. caninum. There was no statistically significant difference in the rate of T. gondii or N. caninum seroreactivity between epileptic and non‐epileptic dogs.Clinical SignificanceThe results obtained do not seem to support the role of T. gondii and N. caninum as causative agents of dog epilepsy.