bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applicability of Start Codon Targeted (SCoT) markers for the assessment of genetic diversity in bread wheat germplasm
Authors: Altaf Muhammad Tanveer , Nadeem Muhammad Azhar , Ali Amjad , Liaqat Waqas , Bedir Mehmet , Baran Nurettin , Ilić Aleksandra , Ilyas Muhammad Kashif , Ghafoor Abdul , Dogan Hamide , Aasim Muhammad , Baloch Faheem Shehzad 
Published: June 2024

Abstract
Research endeavors focused on examining genetic diversity play a pivotal role in advancing agricultural practices, as they furnish valuable insights for breeding programs and the preservation of germplasm. Wheat holds significant global importance as a cereal crop, serving as a primary source of sustenance for almost one-third of the global human population. In the current study, a total of 80 bread wheat genotypes were characterized using the start codon targeted (SCoT) marker system. A set of 14 polymorphic primers yielded a cumulative count of 399 bands with an average of 28.05 bands per primer. The range of diversity markers, such as polymorphism information content (0.26–0.59), effective numbers of alleles (1.27–1.59), Shannon’s information index (0.30–0.51), and gene diversity (0.18–0.34), provided evidence of elevated genetic differences within the examined germplasm. According to the findings of the molecular variance analysis, greater genetic variations are found within populations (92%). The model-based structural approach partitioned the 80 bread wheat genotypes into two distinct populations (Population A and B). The diversity indices based on the structures of the populations revealed that population A had greater diversity compared to population B. Both the principal coordinate analysis and the neighbor-joining analysis also differentiated the 80 different bread wheat genotypes based on their respective collection points. The present crop diversity offers great opportunities for enhancing crop quality and increasing tolerance to environmental challenges, both of which will lead to a reduction in the problem of food insecurity.
Enhancing glucose oxidation: exploring 3D Pt nanowire frameworks for electrochemical studies
Authors: Zaman Tamseel , Akbar Samina , White Joshua S. , Nandhakumar Iris 
Published: June 2024

AbstractHere, we report the use of highly reproducible free-standing 3D Pt nanowire frameworks (3D Pt NFs) to investigate the electrochemical oxidation of glucose. To create this unique Pt NFs, we utilize a lipidic bicontinuous cubic phase as a template. The resulting Pt NFs exhibits a unique 3D single diamond morphology with Fd3m symmetry. This intricate structure provides a large surface area and high electrocatalytic efficiency, making it more sensitive to glucose detection. Small Angle X-ray Scattering and Transmission electron microscopy investigations provided valuable insights into the nanoarchitecture of 3D Pt NFs. It highlights the interconnected nature of the nanowires and showcases the potential for optimized electrochemical performance. Very high current densities are registered for the glucose oxidation reactions at 3D Pt NFs during cyclic voltammetry investigations. This knowledge aids in the design and development of advanced electrocatalytic systems, fuel cells, biosensors, and other devices that leverage the unique characteristics of the 3D Pt framework.
Graphical abstract
This study explores 3D Pt NFs for electrochemical glucose oxidation. Using a phytantriol template with two non-intersecting aqueous channels (A), Pt is electrodeposited in one channel (B), resulting in the formation of 3D Pt NFs after template washing (C). This approach demonstrates the potential for efficient glucose oxidation in the structured nanowire frameworks.
Fabrication of smooth SAC305 thin film via magnetron sputtering
Authors: Ojha M. , Elmustafa A. A. 
Published: June 2024

AbstractSAC305 (96.5 wt% Sn, 3 wt% Ag, 0.5 wt%Cu) solder is increasingly becoming popular due to its reliability good characteristics and performance in addition to the environmental concerns and regulations that restrict the use of lead in nano/microelectronic products. In nano/microelectronics, manufacturing smooth solder coatings free of defects such as voids and cracks, which can compromise joint reliability is crucial. Magnetron sputtering offers a high degree of control over film thickness and composition, resulting in films with excellent uniformity and adhesion. Despite these advantages, fabricating continuous and robust SAC305 films using magnetron sputtering remains a difficult task with limited research addressing these Challenges. To address these challenges and obtain an enhanced surface morphology property, we focus on fabricating SAC305 thin films by optimizing the magnetron sputtering parameters including sputtering power and pressure, and by using various substrates. Field emission-scanning electron microscopy imaging, energy-dispersive X-ray spectroscopy, X-ray diffraction, and atomic force microscopy were used to evaluate the quality of the thin films.
Perioperative ROTEM® evaluation in a patient affected by severe VII factor deficiency undergoing microvascular decompression craniotomy for hemifacial spasm
Authors: Introna Michele , Broggi Morgan , Ferroli Paolo , Martino Donato , Pinto Carmela , Carpenedo Monica , Gemma Marco 
Published: June 2024

AbstractThe potential use of TEG/ROTEM® in evaluating the bleeding risk for rare coagulation disorders needs to be assessed, considering the common mismatch among laboratory tests and the clinical manifestations. As a result, there is currently no published data on the use of viscoelastic tests to assess coagulation in FVII deficient patients undergoing elective neurosurgery. We describe the case of a patient affected by severe FVII deficiency who underwent microvascular decompression (MVD) craniotomy for hemifacial spasm (HFS). The ROTEM® did not show a significant coagulopathy according to the normal ranges, before and after the preoperative administration of the recombinant activated FVII, but a substantial reduction in EXTEM and FIBTEM Clotting Times was noted. The values of coagulation in standard tests, on the contrary, were indicative of a coagulopathy, which was corrected by the administration of replacement therapy. Whether this difference between ROTEM® and standard tests is due to the inadequacy of thromboelastographic normal ranges in this setting, or to the absence of clinically significant coagulopathy, has yet to be clarified. Neurosurgery is a typical high bleeding risk surgery; additional data is required to clarify the potential role for thromboelastographic tests in the perioperative evaluation of the FVII deficient neurosurgical patients.
Fast flux spectrum unfolding of PFTS of KAMINI: an investigation into the viability of radioisotope production
Authors: Bagchi Subhrojit , Chand Manish , Sen Sujoy , Khan Bilal Hassan , Rao J. S. Brahmaji , Kumar G. V. S. Ashok 
Published: June 2024

AbstractThe fast component (0.7–18 MeV) of the neutron spectrum at the Pneumatic Fast Transfer System (PFTS) in the KAMINI reactor was determined by irradiating threshold activation foils. The acquired reaction rates are subsequently unfolded using SAND-II code. The KAMINI reactor was modelled in the MCNP-4B code for an estimate of neutron spectrum at the PFTS location, which was subsequently used as the initial apriori solution for the SAND-II code. The unfolded fast component spectrum at the PFTS was found to be similar to that of the fast benchmark GODIVA and JEZEBEL-23. Moreover, the investigation is substantiated by incorporating modified spectra to estimate the theoretical yield of radioisotopes 32P at PFTS using a Monte Carlo simulation against its experimental yield. The results agree with an accuracy of 6%, affirming the credibility of the derived spectrum. Theoretical yields of 89Sr, 64Cu, and 47Sc were also estimated at the same location.
Insights into dielectric and electrical conductivity dynamics in sol-gel synthesized Ba0.75Ni0.25Tc0.88Mn0.12O3 perovskite ceramic
Authors: Tayari Faouzia , Nassar Kais Iben , Benamara Majdi , Ben Moussa Sana , Alzahrani Abdullah Yahya Abdullah , Teixeira Silvia Soreto , Graça M. P. F. 
Published: June 2024

AbstractThis study presents a comprehensive investigation into the structural, morphological, and electrical properties of sol-gel synthesized Ba0.75Ni0.25Tc0.88Mn0.12O3 perovskite ceramic (BNTMO). The meticulous preparation protocol, involving solvating various precursors, was followed by an extensive characterization employing X-ray diffraction, scanning electron microscopy, and dielectric studies. XRD analysis affirmed the single-phase single-phase cubic structure with Pm-3m space, while SEM revealed a well-defined morphology with an average particle size of 243 nm. The electrical conductivity exploration, elucidated through Jonscher’s universal power law, provided insights into charge carrier dynamics, exhibiting semiconductor behavior. Impedance spectroscopy unraveled a distinctive relaxation peak, corroborated by Cole-Cole plots, unveiling a unique charge carrier mechanism. Dielectric studies showcased intriguing polarization dynamics, indicating promising applications in energy storage. The convergence of activation energy values from various analyses underscores the coherence in the charge carrier relaxation process. Overall, our findings contribute to a nuanced understanding of the electrical intricacies of BNTMO, presenting avenues for its utilization in advanced technological applications.
Graphical Abstract
Efficient fabrication of paper nanocomposites for superior flame retardancy and strengthening properties
Authors: Hassan Mayar , Diab Mohamed A. , Attia Nour F. , Hegazi Abdelrahman H. , Hagar Mohamed 
Published: June 2024

AbstractInnovative and cost-effective paper sheets with superior fire safety and reinforcement properties have been developed. The paper sheets were fabricated via valorization of agricultural waste to paper and then coated with nanoparticles. Paper attained from rice straw was used to create the sheets. Afterward, bentonite sheets were incorporated in these sheets, and finally, PbO nanoparticles were coated on prepared paper nanocomposites. The mass ratio of bentonite sheets was altered. The flammability and mechanical properties of the developed paper nanocomposites were studied. The flame retardancy of developed paper nanocomposite was significantly improved achieving LOI value of 24% compared to 20% for bentonite and PbO nanoparticle-free sample. Additionally, the tensile strength was improved recording 44% enhancement compared to unmodified sample. Furthermore, the flame retardancy mechanism was proposed and studied.
Is vehicle weight associated with risky driving behavior? Analysis of complete national records
Authors: Steren Aviv , Rosenzweig Stav , Rubin Ofir D. 
Published: June 2024

AbstractA clear trend of shifting towards larger, heavier vehicles on roads fuels what has been described as an “arms race.” While larger, heavier vehicles have been shown to benefit the safety of users in the event of a car crash, it is likely that consumers’ experience of this increased safety will lead to behavioral adaptation towards more risky driving behavior. Using complete national data of the car fleet and police-issued speeding tickets over the course of an entire calendar year in Israel, we examined the association between vehicle mass and risky driving behavior in terms of speeding tickets. Controlling for consumers’ choice of car, our results indicate a positive association between vehicle mass and speeding tickets, suggesting that larger, heavier vehicles are associated with risky driving behavior.
Understanding plant tolerance to aluminum: exploring mechanisms and perspectives
Authors: Kocjan Anna , Kwasniewska Jolanta , Szurman-Zubrzycka Miriam 
Published: June 2024

AbstractAluminum (Al) is the third, most abundant element in the Earth's crust. When soil pH drops below 5.5, Al is released from minerals, which threatens plant growth. The roots are particularly vulnerable to Al stress because Al ions can penetrate them, causing growth reduction by inhibiting the cell cycle and decreasing root cell elongation. Al has the ability to bind to cell structures, including cell walls, cytoskeleton, or DNA, which disturb their functions. Plants have developed various response strategies, such as the exclusion of organic acids into the rhizosphere or the detoxification of Al in the vacuole. STOP1 (Sensitive To Proton Rhizotoxicity 1) is the critical regulator of the expression of tolerance-related genes and is present in both mono- and dicots plants. The activity of STOP1 can be regulated on post-transcription and post-translation levels. This review paper presents an overview of the latest literature, aiming to accurately present the problem of Al toxicity and its effect on plant functioning. Moreover, the well-studied mechanisms of plant response and future prospects, like the use of polyamines, miRNAs, or DDR (DNA Damage Response) pathway, will be presented, which are opportunities to develop new plant varieties that are tolerant to Al stress.
Patient-reported outcome and experience domains for diagnostic excellence: a scoping review to inform future measure development
Authors: Dukhanin Vadim , Gamper Mary Jo , Gleason Kelly T. , McDonald Kathryn M. 
Published: June 2024

Abstract
Purpose
“Diagnostic excellence,” as a relatively new construct centered on the diagnostic process and its health-related outcomes, can be refined by patient reporting and its measurement. We aimed to explore the scope of patient-reported outcome (PRO) and patient-reported experience (PRE) domains that are diagnostically relevant, regardless of the future diagnosed condition, and to review the state of measurement of these patient-reported domains.

Methods
We conducted an exploratory analysis to identify these domains by employing a scoping review supplemented with internal expert consultations, 24-member international expert convening, additional environmental scans, and the validation of the domains’ diagnostic relevance via mapping these onto patient diagnostic journeys. We created a narrative bibliography of the domains illustrating them with existing measurement examples.

Results
We identified 41 diagnostically relevant PRO and PRE domains. We classified 10 domains as PRO, 28 as PRE, and three as mixed PRO/PRE. Among these domains, 19 were captured in existing instruments, and 20 were captured only in qualitative studies. Two domains were conceptualized during this exploratory analysis with no examples identified of capturing these domains. For 27 domains, patients and care partners report on a specific encounter; for 14 domains, reporting relates to an entire diagnostic journey over time, which presents particular measurement opportunities and challenges.

Conclusion
The multitude of PRO and PRE domains, if measured rigorously, would allow the diagnostic excellence construct to evolve further and in a manner that is patient-centered, prospectively focused, and concentrates on effectiveness and efficiency of diagnostic care on patients’ well-being.
Two Ships of Theseus
Authors: Dranseika Vilius 
Published: June 2024

AbstractBased on a large cross-cultural study, David Rose et al. (in: Lombrozo et al. (eds) Oxford studies in experimental philosophy, Vol. 3, Oxford University Press, Oxford, pp. 158–174, 2020) argue that the Ship of Theseus story is a genuine puzzle in the sense that people who consider it feel inclined to assert two prima facie inconsistent propositions (Ambivalence). In response, Marta Campdelacreu et al. (Dialectica 74(3):551–559, 2020) argue that the data reported by Rose et al. (2020) fail to support Ambivalence. Namely, the data show sharp interpersonal disagreement among different readers of the Ship of Theseus story, but they fail to demonstrate an intrapersonal conflict or indecision. Should intrapersonal Ambivalence be demonstrated, this, according to Campdelacreu et al. (2020), would be a good indicator of the presence of a puzzle. Here, I provide empirical evidence for intrapersonal Ambivalence about the Ship of Theseus story.
The role of trophic, mutualistic, and competitive interactions in an industrial symbiosis process implementation: an ecological network perspective
Authors: Escandon-Barbosa Diana , Salas-Paramo Jairo , Paque Victor Castrillon 
Published: June 2024

AbstractFor both government and private institutions, the development of collaboration networks becomes an element of great importance for the implementation of related policies such as the circular economy and sustainable practices in manufacturing. Despite the above, such initiatives have not received as much attention in literature but have been decisive as both public and private initiatives. Initiatives in Latin America do not escape this scenario, especially in the creation of conditions that allow the promotion of approaches such as industrial symbiosis. In this way, the present research is aimed at identifying the role of trophic, mutualistic, and competitive interactions in an industrial symbiosis process implementation. A network analysis model is used to achieve this purpose. This technique allows us to know the degree of importance of the different actors that are part of a network, as well as the factors that determine the implementation of initiatives such as industrial symbiosis. Among the results are that empirical findings confirm the presence of trophic interactions that enhance resource efficiency, mutualistic interactions fostering collaboration and synergy, and competitive interactions promoting efficiency and dynamism. Additionally, a green culture, business size, and innovation activities are revealed as influential factors amplifying network dynamics.
Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake
Authors: Smith Daniel L. , Mitchell Sharon E. , Johnson Maria S. , Gibbs Victoria K. , Dickinson Stephanie , Henschel Beate , Li Rui , Kaiser Kathryn A. , Chusyd Daniella E. , Brown Andrew W. , Allison David B. , Speakman John R. , Nagy Tim R. 
Published: June 2024

AbstractCaloric restriction (CR) results in reduced energy and protein intake, raising questions about protein restriction’s contribution to CR longevity benefits. We kept ad libitum (AL)–fed male C57BL/6J mice at 27°C (AL27) and pair-fed (PF) mice at 22°C (22(PF27)). The 22(PF27) group was fed to match AL27 while restricted for calories due to cold-induced metabolism. The 22(PF27) mice had significantly lower body weight, lean mass, fat mass, leptin, IGF-1, and TNF-α levels than AL27 mice (p<0.001 for all). Manipulations over ~11 weeks resulted in significant differences in body temperature, physical activity, and expression of key genes linked to hunger in the hypothalamus. Survival was significantly greater in 22(PF27) compared to AL27 overall (p<0.001). CR in the context of equivalent energy and protein intake resulted in hormonal, metabolic, and physiological benefits and extended longevity. Hence, energy imbalance, rather than low energy or protein intake per se, mediates the benefits of CR.
Luxury application of biochar does not enhance rice yield and methane mitigation: a review and data analysis
Authors: Pia Husna Israt , Baek Nuri , Park Seo-Woo , Shin Eun-Seo , Lee Sun-Il , Kim Han-Yong , Tang Shuirong , Cheng Weiguo , Kwak Jin-Hyeob , Park Hyun-Jin , Choi Woo-Jung 
Published: June 2024

Abstract
Purpose
It is unclear whether a higher biochar (BC) application rate enhances rice (Oryza sativa L.) yield and reduces CH4 emissions. This study investigated changes in rice yield and CH4 emissions with varying BC application rates.

Methods
Data on rice yield and CH4 emission from paddies amended with or without BC were collected from the literature, and the biochar effects were analyzed using the data set.

Results
Across the biochar application rate from 2 to 48 t ha-1, the rice yield increased (by 10.8%) while the area-scaled (by 14.4%) and yield-scaled CH4 emission (by 22.2%) decreased. However, the correlation of BC application rates with rice yield and CH4 mitigation was not significant, implying that a higher BC application rate did not enhance rice yield and CH4 reduction. Interestingly, for a data set showing increased rice yield and decreased CH4 emission by BC, the magnitude of change in the rice yield and CH4 mitigation per unit weight of BC (1 t ha-1) decreased with an increase in the BC application rate. These results suggest that BC effects on rice yield and CH4 mitigation are not additive, probably because of the decreases in the inherent capacity of unit weight of BC to enhance rice yield and reduce CH4 emission, which might be caused by the adverse effects of toxic compounds contained in BC, losses of BC, and a higher degree of nutrient immobilization by BC.

Conclusions
Annual BC application at a low rate (e.g., 2 t ha-1) rather than a luxury application may be an effective and economical strategy for long-term rice yield enhancement and CH4 mitigation using BC.
Machine learning models’ assessment: trust and performance
Authors: Sousa S. , Paredes S. , Rocha T. , Henriques J. , Sousa J. , Gonçalves L. 
Published: June 2024

Abstract
The common black box nature of machine learning models is an obstacle to their application in health care context. Their widespread application is limited by a significant “lack of trust.” So, the main goal of this work is the development of an evaluation approach that can assess, simultaneously, trust and performance. Trust assessment is based on (i) model robustness (stability assessment), (ii) confidence (95% CI of geometric mean), and (iii) interpretability (comparison of respective features ranking with clinical evidence). Performance is assessed through geometric mean. For validation, in patients’ stratification in cardiovascular risk assessment, a Portuguese dataset (N=1544) was applied. Five different models were compared: (i) GRACE score, the most common risk assessment tool in Portugal for patients with acute coronary syndrome; (ii) logistic regression; (iii) Naïve Bayes; (iv) decision trees; and (v) rule-based approach, previously developed by this team. The obtained results confirm that the simultaneous assessment of trust and performance can be successfully implemented. The rule-based approach seems to have potential for clinical application. It provides a high level of trust in the respective operation while outperformed the GRACE model’s performance, enhancing the required physicians’ acceptance. This may increase the possibility to effectively aid the clinical decision.

Graphical abstract
The Nexus of ISTE Standards and Academic Progress: A Mapping Analysis of Empirical Studies
Authors: Crompton Helen , Burke Diane 
Published: June 2024

AbstractTechnology has become commonplace in K-12 classrooms with students actively using digital technology to support learning. The purpose of this study was to investigate whether there is empirical support that implementing the ISTE Standards for Students can result in learning gains. A scoping review methodology was used to map extant literature to evidence of learning gains. To ensure transparency in the selection of the articles and the evidence gathering procedure, an a priori method was used. This study is unique in that it provides the first examination of a set of student standards for technology use to learning gains within empirical articles. The findings reveal that there is evidence that all seven of the standards can lead to learning gains. This study is helpful in providing direction and guidance for all, such as educational leaders, teachers, administrators, researchers and policy makers who are looking for a roadmap for effective technology integration that leads to student success.