bluuebunny/crossref_metadata_2025_split huggingface dataset:
“I felt like a little kind of jolt of energy in my chest”: embodiment in learning in continuing professional development for general practitioners
Authors: Vestergaard Stense Kromann , Risor Torsten 
Published: April 2024

AbstractLearning in medical education encompasses a broad spectrum of learning theories, and an embodiment perspective has recently begun to emerge in continuing professional development (CPD) for health professionals. However, empirical research into the experience of embodiment in learning in CPD is sparse, particularly in the practice of general medicine. In this study, we aimed to explore general practitioners’ (GPs’) learning experiences during CPD from an embodiment perspective, studying the appearance of elements of embodiment—the body, actions, emotions, cognition, and interactions with the surroundings and others—to build an explanatory structure of embodiment in learning. We drew on the concepts of embodied affectivity and mutual incorporation to frame our understanding of embodiment. Four Danish and three Canadian GPs were interviewed to gain insight into specific learning experiences; the interviews and the analysis were inspired by micro-phenomenology, augmented with a complex adaptive systems approach. We constructed an explanatory structure of learning with two entrance points (disharmony and mundanity), an eight-component learning phase, and an ending phase with two exit points (harmony and continuing imbalance). All components of the learning phase—community, pride, validation, rehearsal, do-ability, mind-space, ambiance, and preparing for the future—shared features of embodied affectivity and mutual incorporation and interacted in multi-directional and non-linear ways. We discuss integrating the embodiment perspective into existing learning theories and argue that CPD for GPs would benefit from doing so.
Recommendations for 46,XX Congenital Adrenal Hyperplasia Across Two Decades: Insights from the North American Differences of Sex Development Clinician Survey
Authors: Gardner Melissa , Khorashad Behzad Sorouri , Lee Peter A. , Kogan Barry A. , Sandberg David E. 
Published: April 2024

AbstractSeveral aspects of clinical management of 46,XX congenital adrenal hyperplasia (CAH) remain unsettled and controversial. The North American Disorders/Differences of Sex Development (DSD) Clinician Survey investigated changes, over the last two decades, in clinical recommendations by specialists involved in the management of newborns with DSD. Members of the (Lawson Wilkins) Pediatric Endocrine Society and the Societies for Pediatric Urology participated in a web-based survey at three timepoints: 2003–2004 (T1, n = 432), 2010–2011 (T2, n = 441), and 2020 (T3, n = 272). Participants were presented with two clinical case scenarios—newborns with 46,XX CAH and either mild-to-moderate or severe genital masculinization—and asked for clinical recommendations. Across timepoints, most participants recommended rearing the newborn as a girl, that parents (in consultation with physicians) should make surgical decisions, performing early genitoplasty, and disclosing surgical history at younger ages. Several trends were identified: a small, but significant shift toward recommending a gender other than girl; recommending that adolescent patients serve as the genital surgery decision maker; performing genital surgery at later ages; and disclosing surgical details at younger ages. This is the first study assessing physician recommendations across two decades. Despite variability in the recommendations, most experts followed CAH clinical practice guidelines. The observation that some of the emerging trends do not align with expert opinion or empirical evidence should serve as both a cautionary note and a call for prospective studies examining patient outcomes associated with these changes.
Terrestrial and marine POC export fluxes estimated by 234Th–238U disequilibrium and δ13C measurements in the East China Sea shelf
Authors: Zhong Qiangqiang , Huang Dekun , Wang Qiugui , Du Jinzhou , Zhang Fule , Lin Jing , Yu Tao 
Published: April 2024

AbstractThe use of 234Th–238U disequilibrium has been widely employed to estimate the sinking flux of particulate organic carbon (POC) from the upper sea and ocean. Here, the deficits of 234Th relative to 238U in the water column and the carbon isotope signature (δ13C) of POC in the East China Sea (ECS) Shelf were measured, which was used to distinguish the fraction of marine and terrestrial POC export fluxes. In the ECS Shelf, very strong deficits of 234Th relative to 238U were observed throughout the water column, with 234Th/238U activity ratios ranging from 0.158 ± 0.045 to 0.904 ± 0.068 (averaging 0.426 ± 0.159). The residence times of particle reactive radionuclide 234Th (τTh–T) in the ECS shelf water varied between 9 and 44 days, which is significantly shorter than that in the continental slope area or the basin area. This phenomenon indicates that there is a more rapid particle scavenging process in the ECS shelf water compared to the continental slope and basin upper water. By applying a two-end-member mixing model based on the δ13C, the fraction of terrestrial POC was estimated to be 0 to 74% (mean: 30 ± 22%) and the fraction of marine POC was in the range of 25% to 100% (mean: 70 ± 22%). Fluxes of marine and terrestrial POC settling to the seafloor exhibited significant spatial differences among different stations, ranging from 11 to 129 mmol C/m2/day and from 2.6 to 38 mmol C/m2/day, respectively. The averaged terrestrial POC fluxes in the southern and northern ECS Shelf were similar (~ 21 to 24 mmol C/m2/day), while the marine POC fluxes in the north (86 ± 37 mmol C/m2/day) were approximately four times higher than those in the south (26 ± 20 mmol C/m2/day). Interestingly, the estimated export flux of both marine and terrestrial POC were approximately one order of magnitude higher than the previously reported burial fluxes of POC (ranging from 1.1 ± 0.1 to 11.4 ± 1.1 mmol C/m2/day) in the underlying bottom sediments, indicating that the majority (> 90%) of both terrestrial and marine POC exported from the upper water column are degraded in the sediments of the ECS Shelf. This “carbon missing” phenomenon can greatly be attributed to rapid decomposition by other processes (including microbial reworking, cross-shelf transport, and possible consumption by benthic organisms). Our findings highlight the dynamic nature of carbon cycling in the continental shelf and the need for further research to understand these processes and improve carbon budget assessments.
Clinico–pathologic factors and survival of patients with breast cancer diagnosed with de novo brain metastasis: a national cancer database analysis
Authors: Hijazi Ali , Mohanna Mohamed , Sabbagh Saad , Herrán María , Dominguez Barbara , Sarna Kaylee , Nahleh Zeina 
Published: April 2024

Abstract
Purpose
Patients with Breast Cancer (BC) with Brain Metastasis (BCBM) have poor survival outcomes. We aimed to explore the clinico–pathologic and therapeutic factors predicting the survival in patients with de novo BCBM using the National Cancer Database (NCDB).

Patients and methods
The NCDB was queried for patients with BC between 2010 and 2020. Survival analysis with Kaplan–Meier curves and log rank tests were used to find median overall survival (OS) in months (95% CI) across the different variables. A multivariate cox regression model was computed to identify significant predictors of survival.

Results
Out of n = 2,610,598 patients, n = 9005 (0.34%) had de novo BCBM. A trend of decreasing OS was observed with increasing age, Charlson–Deyo score (CDS), and number of extracranial metastatic sites. The highest median OS was observed in the Triple Positive and the lowest OS in the Triple Negative subgroup. Based on treatment regimen, combination of systemic therapy and local therapy achieved the highest OS. A positive trend in OS was observed in the BC subgroup analysis with targeted therapy demonstrating a survival benefit when added to systemic therapy.
The multivariate cox regression model showed that age, race, ethnicity, insurance, median income, facility type, CDS, BC subtype, metastatic location sites, and treatment combinations received were significantly associated with risk of death. Receiving only local treatment for BM without systemic therapy more than doubled the risk of death compared to combining it with systemic therapy.

Conclusions
This analysis suggests that treatment of systemic disease is the major factor influencing survival in patients with BCBM. Moreover, targeted therapy with anti–HER2 increased survival when added to systemic therapy explaining the highest median OS noted in the Triple Positive subgroup.
Beach day or deadly heatwave? Content analysis of media images from the 2021 Heat Dome in Canada
Authors: Tetzlaff Emily J. , Goulet Nicholas , Yapici Nihal , Gorman Melissa , Richardson Gregory R.A. , Enright Paddy M. , Kenny Glen P. 
Published: April 2024

AbstractDuring extreme heat events (EHEs) the public often learns about health protective actions through the media. Visual news coverage can act as a powerful tool to help convey complex health protective actions to the public. Despite the importance of images in helping the public understand the risk, there has been no systematic analysis to assess what images have been used by media outlets in Canada during EHEs. This paper helps to fill that gap by analyzing how the Canadian media visually communicated the risks of extreme heat to the public during the unprecedented 2021 Heat Dome. A review of thousands of online news media articles published about the 2021 Heat Dome in Canada was conducted on five subscription news databases. Overall, 845 images were coded to identify denotative, connotative, and ideological content. Only 16% of these published images implied that heat was dangerous, of which only 40% depicted people, and 46% implied human suffering. Our findings demonstrate that the majority of images used in Canadian news coverage on the 2021 Heat Dome are incompatible with, and frequently contradict, evidence-based heat protective actions. Governments, public health agencies, and other stakeholders engaged in distributing heat preparedness messaging (e.g., journalists) should prioritize improving the images of extreme heat in news coverage to align with evidence-based public health messages. With rising global temperatures due to climate change and the associated increases in the frequency and intensity of extreme heat events, prioritizing these actions is critically important to offset the threat posed to public health.
Special directions on the finite affine plane
Authors: Kiss Gergely , Somlai Gábor 
Published: April 2024

AbstractIn this paper we study the number of special directions of sets of cardinality divisible by p on a finite plane of order p, where p is a prime. We show that there is no such a set with exactly two special directions. We characterise sets with exactly three special directions which answers a question of Ghidelli in negative. Further we introduce methods to construct sets of minimal cardinality that have exactly four special directions for small values of p.
A multi-metric approach to characterize variability in Yellow Perch (Perca flavescens) use of Lake Ontario and two barrier-protected coastal wetlands
Authors: Wilson Kylee B. , Altenritter Matthew E. 
Published: April 2024

AbstractYellow Perch (Perca flavescens) inhabit both nearshore and coastal wetland habitats of the Laurentian Great Lakes throughout their lifetime and are known to exhibit different movement life histories. However, uncertainty persists in the spatial extent of this variation and in the duration of habitat use. To explore these uncertainties, we used a multi-metric approach that included water and otolith microchemistry and tissue stable isotope ratios (δ13C, δ15N). The ratio of manganese to calcium in otoliths was used to identify transitional movements between nearshore Lake Ontario and wetland habitats while carbon and nitrogen tissue isotope ratios revealed variable duration of wetland inhabitance. Our research suggests that the multi-metric approach was useful for addressing questions that could not be answered by one method alone. Our results demonstrate individual differences in duration of coastal wetland habitat residence among Yellow Perch, which may influence their susceptibility to recreational harvest. As Yellow Perch are an important species of consideration for management agencies such as the Great Lakes Fishery Commission, exposing such diversity is important when considering the potential for differential contributions of individuals with variable movement life histories to overall population stability and resilience over time.
First report of four dagger nematode species of the genus Xiphinema (Nematoda: Longidoridae) from banana in Syria using an integrative approach
Authors: Ali Nadine , Vicente Cláudia S. L. , Mota Manuel , Gutiérrez-Gutiérrez Carlos 
Published: April 2024

AbstractA nematological survey was conducted between 2021 and 2022 in banana fields distributed in two major banana-producing regions in the western coast of Syria. As a result, six populations of Xiphinema spp. identified as X. diffusum, X. pachtaicum, X. simile, X. vuittenezi and X. zagrosense were isolated from the rhizosphere of banana plants (Musa sp.) and characterized using morphological and molecular data based on two rRNA genes (D2–D3 expansion segments of the 28S, and ITS fragments) and partial region of the cytochrome oxidase I gene (COI mtDNA) sequences. Moreover, the molecular identification of the endosymbionts of these populations was also performed using the complete 16S rDNA gene. The phylogenetic relationships of the recovered species of nematodes and respective endosymbionts were reconstructed. Candidatus Xiphinematobacter sp. (OR196969; OR196971) and Ca. Xiphinematobacter sp. (OR196970) were detected in X. diffusum and X. simile, respectively, and clustered together with other Ca. Xiphinematobacter sp.A and sp.I respectively. To our knowledge, this is the first report of X. diffusum, X. simile, X. vuittenezi and X. zagrosense parasitizing banana in Syria, extending the geographical distribution of these species within the Mediterranean Basin.
The Link between Family Financial Socialization in Adulthood and Investment Literacy of P2P Investors
Authors: Legenzova Renata , Leckė Gintarė 
Published: April 2024

AbstractThis paper examines how family financial socialization in adulthood is linked to the development of investment literacy among individual family members within the context of innovative financial services, specifically peer-to-peer (P2P) lending. Our findings revealed that P2P lending investors engage in a moderate level family financial socialization suggesting that family, as a key financial socialization agent in childhood and adolescence, maintains its role in adulthood. Additionally, such investors possess a high-level investment knowledge, skills, and attitudes. Explicit family financial socialization has a significant and positive effect on the individuals’ investment knowledge, skills, and attitudes, while the effect of implicit financial socialization is significant but negative for knowledge and attitudes. Such findings suggest that family discussion among adult members result in higher, while observations of family members’ investment behavior led to lower investment literacy. Our study found no significant moderating effect of the strength of social ties indicating that dynamics of family relations neither strengthen nor weaken proximal socialization outcomes. The analysis of differences across demographic groups unveiled statistically significant distinctions concerning respondents’ gender, income, and education. These results provide important insights for stakeholders, underscoring the significant role family socialization in adulthood plays in shaping individuals’ investment literacy, particularly of those investing on P2P lending platforms.
Navigating Through the Digital Workplace: Measuring Leader Digital Competence
Authors: op ´t Roodt Helen , Bracht Eva M. , van Dick Rolf , Hernandez Bark Alina S. 
Published: April 2024

Abstract
In a modern digital workplace, leaders must have the necessary skills to lead employees virtually. Despite its high practical and theoretical relevance, a consensus on crucial digital competencies for virtual leaders is lacking, hindering a systematic exploration of the leader’s role in facilitating technology use. In the present article, we propose a new concept and instrument to assess leader digital competence (LDC). After reviewing the literature, we establish three dimensions of LDC, centering around the leader’s ability and inclination to select, promote, and enable technology and digital media among their employees. We provide support for the scale's convergent, discriminant, criterion-related, and incremental validity using four independent samples (N

1
= 156, N

2
= 309, N

3
= 201, N

4 employee = 452, N

4 leader = 93). Furthermore, results support the reliability and factor structure with the three proposed dimensions of the 10-item LDC scale. The findings demonstrate that the scale represents a psychometrically sound instrument, useful for further examining conditions for effectiveness in the virtual environment. Future research should aim to advance the understanding of antecedents and situational factors that influence the relevance of LDC and its impact on employee, team, and organizational outcomes.
Fourth-Order Conservative Non-splitting Semi-Lagrangian Hermite WENO Schemes for Kinetic and Fluid Simulations
Authors: Zheng Nanyi , Cai Xiaofeng , Qiu Jing-Mei , Qiu Jianxian 
Published: April 2024

AbstractWe present fourth-order conservative non-splitting semi-Lagrangian (SL) Hermite essentially non-oscillatory (HWENO) schemes for linear transport equations with applications for nonlinear problems including the Vlasov–Poisson system, the guiding center Vlasov model, and the incompressible Euler equations in the vorticity-stream function formulation. The proposed SL HWENO schemes combine a weak formulation of the characteristic Galerkin method with two newly constructed HWENO reconstruction methods. The new HWENO reconstructions are meticulously designed to strike a delicate balance between curbing numerical oscillation and introducing excessive dissipation. Mass conservation naturally holds due to the weak formulation of the semi-Lagrangian discontinuous Galerkin method and the design of the HWENO reconstructions. We apply a positivity-preserving limiter to maintain the positivity of numerical solutions when needed. Abundant benchmark tests are performed to verify the effectiveness of the proposed SL HWENO schemes.
Green and Atom Economical Route to High Compressive Strength Lignin Oil-Sulfur Composites
Authors: Tisdale Katelyn A. , Dona Nawoda L. Kapuge , Maladeniya Charini P. , Smith Rhett C. 
Published: April 2024

AbstractLignin is the most abundant natural source of aromatics but remains underutilized. Elemental sulfur is a plentiful by-product of fossil fuel refining. Herein we report a strategy for preparing a durable composite by the one-pot reaction of elemental sulfur and lignin oil comprising lower molecular weight lignin derivatives. A lignin oil-sulfur composite (LOS90) was prepared by reacting 10 wt. % lignin oil with 90 wt. % elemental sulfur. The composite could be remelted and reshaped over several cycles without loss of properties. Results from the study showed that LOS90 has properties competitive with or exceeding values for commercial ordinary Portland cement and brick formulations. For example, LOS90 displayed impressive compressive strength (22.1 MPa) and flexural strength (5.7 MPa). LOS90 is prepared entirely from waste materials with 98.5% atom economy of composite synthesis, a low E factor of 0.057, and lignin char as the only waste product of the process for its preparation. These results suggest the potential applications of lignin and waste sulfur in the continuous efforts to develop more recyclable and sustainable materials.
Understanding university-industry collaboration: a social exchange perspective on the entrepreneurial university
Authors: Marques Carla Susana , Ferreira João J. , Marques Carlos Peixeira , Leal Carmem 
Published: April 2024

AbstractThe aim of this study is threefold: firstly, to assess how the support provided by universities for academic collaboration with the industry may foster collaborative behaviour, based on academics’ perceptions of the benefits and costs of collaboration. Secondly, the research seeks to unravel the perceived benefits and costs of university-industry (U-I) collaboration among academic staff within three distinct Higher Education Institutes (HEI) located in three different countries. Thirdly, analyse the impacts of these perceived benefits and costs on U-I collaboration behaviour. To reach these purposes, this study used a quantitative approach involving 214 academic staff from three HEI located in Portugal, Poland, and Türkiye, who answered a questionnaire about their collaboration behaviours and their perceptions regarding support provided by the HEI and their personal benefits and costs of engaging in collaborative behaviour. Results from a partial least squares structural equation model (PLS-SEM) suggest that perceived support diminishes the costs and favours the benefits. Nevertheless, the perceived collaboration costs generally outweigh the benefits. Increasing U-I collaboration implies a more efficient support and the results from this study point to the need to design a system of extrinsic rewards benefiting the heavy collaborators.
Selenoprotein W engages in overactive osteoclast differentiation in multiple myeloma
Authors: Kim Hyunsoo , Oh Jiin , Kim Min Kyoung , Lee Kyung Hee , Jeong Daewon 
Published: April 2024

Abstract

Background
Patients with multiple myeloma exhibit malignant osteolytic bone disease due to excessive osteoclast formation and function. We recently identified that osteoclastogenic stimulator selenoprotein W (SELENOW) is upregulated via ERK signaling and downregulated via p38 signaling during receptor activator of nuclear factor (NF)-κΒ ligand (RANKL)-induced osteoclast differentiation. In the intrinsic physiological process, RANKL-induced downregulation of SELENOW maintains proper osteoclast differentiation; in contrast, forced overexpression of SELENOW leads to overactive osteoclast formation and function.

Methods and results
We observed that SELENOW is highly expressed in multiple myeloma-derived peripheral blood mononuclear cells (PBMCs) and mature osteoclasts when compared to healthy controls. Also, the level of tumor necrosis factor alpha (TNFα), a pathological osteoclastogenic factor, is increased in the PBMCs and serum of patients with multiple myeloma. ERK activation by TNFα was more marked and sustained than that by RANKL, allowing SELENOW upregulation. Excessive expression of SELENOW in osteoclast progenitors and mature osteoclasts derived from multiple myeloma facilitated efficient nuclear translocation of osteoclastogenic transcription factors NF-κB and NFATc1, which are favorable for osteoclast formation.

Conclusion
Our findings suggest a possibility that feedforward signaling of osteoclastogenic SELENOW by TNFα derived from multiple myeloma induces overactive osteoclast differentiation, leading to bone loss during multiple myeloma.