bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire
Authors: McWilliams Daniel F , Georgopoulos Vasileios , Patel Jayamala , Millar Bonnie , Smith Stephanie L , Walsh David A 
Published: June 2024

Abstract

Background
Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnaire (CAP) to characterize this across painful musculoskeletal conditions.

Methods
CAP was derived from the 8-item CAP-Knee questionnaire, and completed by participants with joint pain in the Investigating Musculoskeletal Health and Wellbeing survey. Subgroups had OA, back pain or FM. Acceptability was evaluated by feedback and data missingness. Correlation coefficients informed widespread pain scoring threshold in relation to the other items, and evaluated associations with pain. Factor analysis assessed CAP structure. Intraclass Correlation Coefficient (ICC) between paper and electronic administration assessed reliability. Friedman test assessed score stability over 4 years in people reporting knee OA.

Results
Data were from 3579 participants (58% female, median age 71 years), including subgroups with OA (n = 1158), back pain (n = 1292) or FM (n = 177). Across the three subgroups, ≥10/26 painful sites on the manikin scored widespread pain. Reliability was high [ICC = 0.89 (95% CI 0.84–0.92)] and CAP scores fit to one- and two-factor model, with a total CAP score that was associated with pain severity and quality (r = 0.50–0.72). In people with knee pain, CAP scores were stable over 4 years at the group level, but displayed significant temporal heterogeneity within individual participants.

Conclusions
Central aspects of pain are reliably measured by the CAP questionnaire across a range of painful musculoskeletal conditions, and is a changeable state.
Generational Dissonance or Cultural Persistence? European Immigration and the Intergenerational Transmission of Gender Beliefs
Authors: McManus Patricia A , van der Does Tamara , Adem Muna 
Published: June 2024

Abstract
Contemporary perspectives on gender highlight the multilevel processes that maintain the gender system, from the hegemonic cultural beliefs embedded in state institutions to the gendered interactions that occur in everyday life. This study investigates immigration as a source of diversity and adaptation in the gender system. Using data on immigrant and native adolescents in the Children of Immigrants Longitudinal Survey in Four European Countries (CILS4EU), we examine the intergenerational transmission of attitudes about the domestic division of labor. Our results show a strong association between mother’s gender attitudes and child’s gender attitudes among both immigrants and natives, with no significant difference between the two groups. The persistence of beliefs grounded in family culture results in significantly higher levels of gender traditionalism among adolescent children of immigrants as compared to their native peers. These results underscore the centrality of families as a relational context that contributes both to the reproduction of cultural beliefs about gender and the slow pace of shifts in hegemonic gender beliefs in response to social change.
Aleppo Buttons and Sulphur Injections: The Politics of Science and Citation in Mandatory Palestine and Transjordan
Authors: Irving Sarah 
Published: June 2024

Summary
This article explores the experiences of two doctors, Jamil Tutunji and Tawfiq Canaan, in their efforts to interact with, contribute to and debate with international colleagues in the medical journals of the 1920s–40s. Respectively from Transjordan and Palestine, both at the time ruled by British colonial administrations under League of Nations Mandates, these men’s work seems to have been ignored or sidelined in favour of that by European or European-Jewish scholars working on similar topics. The resulting trajectories they followed, however, differed significantly, highlighting the shifting opportunities available to scientists of Arab origin in the colonial world of academic publishing, collaboration and citation. Canaan and Tutunji’s engagement with medical research highlights the precarity of their positions as doctors committed to a model of medicine the operation of which was policed by professionals and institutions in the colonial metropole.
Supervision and Prudential Regime of the Banking Sector of Mauritius: An Evaluative Review of Statutes
Authors: Mahadew Bhavna 
Published: June 2024

Abstract
This article provides an evaluative review of the supervision and prudential regime of the banking sector of Mauritius. It assesses the normative framework that provides for the basis of bank supervision in Mauritius using relevant international standards as applicable. It can be observed that the banking sector of Mauritius is quite advanced and compliant with international standards though there is room for improvement. The Bank of Mauritius has been proactive in ensuring that the supervision and prudential regime meets the exigencies of the standards of an international financial centre which Mauritius aspires to be. The aim of this evaluative review is to provide an overview of bank supervision and the prudential regime of Mauritius to the academic and research community since there is a dearth of literature on this aspect coming from Mauritius. Additionally, there are certain lessons that can be learnt from the Mauritian experience regarding bank supervision especially for African countries.
Xylem cell size regulation is a key adaptive response to water deficit in Eucalyptus grandis
Authors: Keret Rafael , Drew David M , Hills Paul N 
Published: June 2024

Abstract
Future climatic scenarios forecast increasingly frequent droughts that will pose substantial consequences on tree mortality. In light of this, drought-tolerant eucalypts have been propagated; however, the severity of these conditions will invoke adaptive responses, impacting the commercially valuable wood properties. To determine what mechanisms govern the wood anatomical adaptive response, highly controlled drought experiments were conducted in Eucalyptus grandis W. Hill ex Maiden, with the tree physiology and transcriptome closely monitored. In response to water deficit, E. grandis displays an isohydric stomatal response to conserve water and enable stem growth to continue, albeit at a reduced rate. Maintaining gaseous exchange is likely a critical short-term response that drives the formation of hydraulically safer xylem. For instance, the development of significantly smaller fibers and vessels was found to increase cellular density, thereby promoting drought tolerance through improved functional redundancy, as well as implosion and cavitation resistance. The transcriptome was explored to identify the molecular mechanisms responsible for controlling xylem cell size during prolonged water deficit. Downregulation of genes associated with cell wall remodeling and the biosynthesis of cellulose, hemicellulose and pectin appeared to coincide with a reduction in cellular enlargement during drought. Furthermore, transcript levels of NAC and MYB transcription factors, vital for cell wall component biosynthesis, were reduced, while those linked to lignification increased. The upregulation of EgCAD and various peroxidases under water deficit did not correlate with an increased lignin composition. However, with the elevated cellular density, a higher lignin content per xylem cross-sectional area was observed, potentially enhancing hydraulic safety. These results support the requirement for higher density, drought-adapted wood as a long-term adaptive response in E. grandis, which is largely influenced by the isohydric stomatal response coupled with cellular expansion-related molecular processes.
Exploring the role of uncertainty regulation strategies to demystify the link between person–environment misfit and late-career outcomes
Authors: Harris America , Davenport Meghan K , Fasbender Ulrike 
Published: June 2024

Abstract
Amidst global workforce aging and uncertain times, retirement systems advocate for the extension of working lives to alleviate labor shortages; simultaneously, older workers may want to or need to work longer. Uncertainty in one’s work ability resulting from person–environment (P–E) misfit may lead to working lives being cut short prematurely unless the uncertainty can be effectively regulated. By extending the uncertainty regulation model to the late-career development context, our study aimed to uncover in what way utilizing uncertainty regulation—opening and closing strategies—may shape late-career outcomes: retirement, bridge employment, and senior entrepreneurship intentions; and to understand how and through which mechanisms late-career outcomes were related to P–E misfit. We tested our preregistered hypotheses using three-wave data from 902 older workers. Results of structural equation modeling showed that P–E misfit predicted uncertainty in work ability, which in turn, predicted the use of opening strategies, but not closing strategies. Opening strategies were negatively linked to retirement intentions and positively linked to bridge employment and senior entrepreneurship intentions. Closing strategies were negatively linked to bridge employment and senior entrepreneurship intentions. Our findings further demonstrated that opening strategies mediated the relationship between uncertainty in work ability resulting from P–E misfit and late-career outcomes. Together, these findings highlight that opening strategies benefit late-career development as they defer retirement, and encourage bridge employment and senior entrepreneurship, thereby extending working lives; while closing strategies hinder bridge employment and senior entrepreneurship, thereby impeding these routes to extend working lives.
The systematics and nomenclature of the Dodo and the Solitaire (Aves: Columbidae), and an overview of columbid family-group nomina
Authors: Young Mark T , Hume Julian P , Day Michael O , Douglas Robert P , Simmons Zoë M , White Judith , Heller Markus O , Gostling Neil J 
Published: June 2024

AbstractThe Dodo and its extinct sister species, the Solitaire, are iconic exemplars of the destructive capabilities of humanity. These secondarily terrestrial columbids became extinct within a century of their first encounter with humanity. Their rapid extinction, with little material retained in natural history collections, led 18th and some early 19th century naturalists to believe that these aberrant birds were mythological. This meant that the nomenclatural publications in which their scientific nomina were established were based on accounts written before the species became extinct. As such, no type specimens were designated for either the Dodo or the Solitaire. Our in-depth historical overview of both species and associated family-group nomina found that the nominal authority of the Dodo-based family group is not what is reported in the literature. Moreover, our detailed review of the family-group nomina based on columbid genera ensures that the current columbid family-group systematization is valid. Changing nomenclatural norms between the 19th and 20th centuries had a profound impact on Dodo nomenclature; so much so that the Dodo is an example of how pervasive nomenclatural ‘ripples’ can be and a warning for our current world of multiple nomenclatural codes.
Variability in Chromosome 1 of Select Moroccan Pyrenophora teres f. teres Isolates Overcomes a Highly Effective Barley Chromosome 6H Source of Resistance
Authors: Li Jinling , Wyatt Nathan A. , Skiba Ryan M. , Kariyawasam Gayan K. , Richards Jonathan K. , Effertz Karl , Rehman Sajid , Liu Zhaohui , Brueggeman Robert S. , Friesen Timothy L. 
Published: June 2024

Barley net form net blotch (NFNB) is a destructive foliar disease caused by Pyrenophora teres f. teres. Barley line CIho5791, which harbors the broadly effective chromosome 6H resistance gene Rpt5, displays dominant resistance to P. teres f. teres. To genetically characterize P. teres f. teres avirulence/virulence on the barley line CIho5791, we generated a P. teres f. teres mapping population using a cross between the Moroccan CIho5791-virulent isolate MorSM40-3 and the avirulent reference isolate 0-1. Full genome sequences were generated for 103 progenies. Saturated chromosome-level genetic maps were generated, and quantitative trait locus (QTL) mapping identified two major QTL associated with P. teres f. teres avirulence/virulence on CIho5791. The most significant QTL mapped to chromosome (Ch) 1, where the virulent allele was contributed by MorSM40-3. A second QTL mapped to Ch8; however, this virulent allele was contributed by the avirulent parent 0-1. The Ch1 and Ch8 loci accounted for 27 and 15% of the disease variation, respectively, and the avirulent allele at the Ch1 locus was epistatic over the virulent allele at the Ch8 locus. As a validation, we used a natural P. teres f. teres population in a genome-wide association study that identified the same Ch1 and Ch8 loci. We then generated a new reference quality genome assembly of parental isolate MorSM40-3 with annotation supported by deep transcriptome sequencing of infection time points. The annotation identified candidate genes predicted to encode small, secreted proteins, one or more of which are likely responsible for overcoming the CIho5791 resistance. [Formula: see text] The author(s) have dedicated the work to the public domain under the Creative Commons CC0 “No Rights Reserved” license by waiving all of his or her rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law, 2024.
Accelerating the continuous community sharing of digital neuromorphology data
Authors: Tecuatl Carolina , Ljungquist Bengt , Ascoli Giorgio A. 
Published: June 2024

AbstractThe tree‐like morphology of neurons and glia is a key cellular determinant of circuit connectivity and metabolic function in the nervous system of essentially all animals. To elucidate the contribution of specific cell types to both physiological and pathological brain states, it is important to access detailed neuroanatomy data for quantitative analysis and computational modeling. NeuroMorpho.Org is the largest online collection of freely available digital neural reconstructions and related metadata and is continuously updated with new uploads. Earlier in the project, we released multiple datasets together yearly, but this process caused an average delay of several months in making the data public. Moreover, in the past 5 years, >80% of invited authors agreed to share their data with the community via NeuroMorpho.Org, up from <20% in the first 5 years of the project. In the same period, the average number of reconstructions per publication increased 600%, creating the need for automatic processing to release more reconstructions in less time. The progressive automation of our pipeline enabled the transition to agile releases of individual datasets as soon as they are ready. The overall time from data identification to public sharing decreased by 63.7%; 78% of the datasets are now released in less than 3 months with an average workflow duration below 40 days. Furthermore, the mean processing time per reconstruction dropped from 3 h to 2 min. With these continuous improvements, NeuroMorpho.Org strives to forge a positive culture of open data. Most importantly, the new, original research enabled through reuse of datasets across the world has a multiplicative effect on science discovery, benefiting both authors and users.
Kinesin motor KIF16A regulates microtubule stability and actin‐dependent spindle migration in mouse oocyte meiosis
Authors: Wang Wei , Shi Zhenhu , Zhang Dandan , Hou Wenwen , Ma Huijie , Liu Xinyu , Zhang Yongteng , Zhu Jinbao , Yang Zaishan , Jia Bo , Xu Qimei , Zhang Yunhai , Zhang Mianqun 
Published: June 2024

AbstractKif16A, a member of the kinesin‐3 family of motor proteins, has been shown to play crucial roles in inducing mitotic arrest, apoptosis, and mitotic cell death. However, its roles during oocyte meiotic maturation have not been fully defined. In this study, we report that Kif16A exhibits unique accumulation on the spindle apparatus and colocalizes with microtubule fibers during mouse oocyte meiotic maturation. Targeted depletion of Kif16A using gene‐targeting siRNA disrupts the progression of the meiotic cell cycle. Furthermore, Kif16A depletion leads to aberrant spindle assembly and chromosome misalignment in oocytes. Our findings also indicate that Kif16A depletion reduces tubulin acetylation levels and compromises microtubule resistance to depolymerizing drugs, suggesting its crucial role in microtubule stability maintenance. Notably, we find that the depletion of Kif16A results in a notably elevated incidence of defective kinetochore‐microtubule attachments and the absence of BubR1 localization at kinetochores, suggesting a critical role for Kif16A in the activation of the spindle assembly checkpoint (SAC) activity. Additionally, we observe that Kif16A is indispensable for proper actin filament distribution, thereby impacting spindle migration. In summary, our findings demonstrate that Kif16A plays a pivotal role in regulating microtubule and actin dynamics crucial for ensuring both spindle assembly and migration during mouse oocyte meiotic maturation.
Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019
Authors: Proctor Dominic W. , Goodall Richard , Borsky Kim , Salciccioli Justin D. , Marshall Dominic C. , Shanmugarajah Kumaran , Shalhoub Joseph 
Published: June 2024

Objective:
The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) of benign gallbladder and biliary diseases across high-income countries between 1990 and 2019.

Background:
Benign gallbladder and biliary diseases place a substantial burden on healthcare systems in high-income countries. Accurate characterization of the disease burden may help optimize healthcare policy and resource distribution.

Materials and methods:
Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and DALYs data for gallbladder and biliary diseases in males and females were extracted from the 2019 Global Burden of Disease (GBD) study. A mortality-incidence index (MII) was also calculated. Joinpoint regression analysis was performed.

Results:
The median ASIRs across the European Union 15+ countries in 2019 were 758/100,000 for females and 282/100,000 for males. Between 1990 and 2019 the median percentage change in ASIR was +2.49% for females and +1.07% for males. The median ASMRs in 2019 were 1.22/100,000 for females and 1.49/100,000 for males with a median percentage change over the observation period of −21.93% and −23.01%, respectively. In 2019, the median DALYs was 65/100,000 for females and 37/100,000 among males, with comparable percentage decreases over the observation period of −21.27% and −19.23%, respectively.

Conclusions:
International variation in lifestyle factors, diagnostic and management strategies likely account for national and sex disparities. This study highlights the importance of ongoing clinical efforts to optimize treatment pathways for gallbladder and biliary diseases, particularly in the provision of emergency surgical services and efforts to address population risk factors.
Research on Detection Efficiency of Imaging Plates for Alpha Particles Using Two Types of Imaging Plate
Authors: Qin Fengdi , He Zhengzhong , Fan Zhongkai , Lu Kejun , Li Haoxuan , Luo Yizhe , Yang Xiyu , Deng Tianyu , Cai Xiangming , Sun Cong , Shan Jian 
Published: June 2024

Abstract
Imaging plates can measure isotopes with alpha decay (such as radon and its progeny, americium, and so on). However, the detection efficiency of imaging plates is affected by alpha particle energy, types of imaging plates, and the overlapping effect. In this study, simulations were performed to analyze the relationship between detection efficiency and these three influence factors. The research findings suggest that BAS-TR and BAS-MS are well-suited for the detection of alpha particles with energy levels below 6.83 MeV and above, respectively. The track overlap effect correction method proposed in this study is applicable to both BAS-TR and BAS-MS image plates. The measurement results of radon progeny demonstrate that the correction method enhances the detection efficiency from 0.203 to 0.288. This study presents a valuable approach for selecting the appropriate image plate and correcting the track overlap effect in the measurement of alpha radioactive material concentration and other related information.
Mini-Scleral Lens: An Effective Mode of Visual Rehabilitation in Eyes With Resolved Hydrops
Authors: Sinha Rajesh , Anjum Shahnaz , Dwivedi Shwetangi , Agarwal Rinky , Bari Aafreen 
Published: June 2024

Objectives:
To evaluate the visual outcome of mini-scleral contact lenses (MSLs) in keratoconus following the resolution of acute hydrops.

Methods:
This was a prospective observational case series of patients of healed hydrops in keratoconus fitted with an MSL (Keracare, Acculens, Lakewood, CO) who were managed for acute hydrops medically or surgically at least 3 months prior. Uncorrected visual acuity, best spectacles-corrected visual acuity, best lens-corrected visual acuity, topographic indices, keratometric indices, contact lens parameters, and ocular aberrometric changes were evaluated. All patients were followed up for at least 3 months.

Results:
Eighteen eyes of 17 patients were included in the analysis. The mean post-hydrops topographic values of the eyes included flat keratometric value (K1) 64.93±10.88 (range 44.30–93.40) diopters (D), steep keratometric value (K2) 70.41±10.92 D (range 45.8–98.6 D), and Kmax of 79.53±17.73 D (range 50–130.2). The final mini-scleral lens's mean dioptric power was −8.56±3.96 D (range −18 to −4). Visual acuity significantly improved from post-hydrops resolution uncorrected visual acuity of 1.5±0.71 logMAR to 0.79±0.18 logMAR best spectacles-corrected visual acuity to 0.27±0.01 logMAR best lens-corrected visual acuity (P-value <0.0001). Similarly, there was considerable improvement in corneal aberrometric values after wearing an MSL. At the 3-month follow-up, 15 patients (16 eyes) were compliant to contact lens use with a minimum of 6 to 8 hr daily while two patients (2 eyes) were poorly compliant.

Conclusions:
A MSL is a valuable option for visual rehabilitation in keratoconus following the resolution of acute hydrops.