bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preliminary Investigation on the Thermodynamic Evaluation and Phase Evolution of Soda Ash-Assisted Roast Treatment of Alluvial Columbite for Recovery of Niobium and Tantalum
Authors: Nzeh Nnaemeka Stanislaus , Popoola Patricia A. I. , Kgwedi Lethabo Christinah , Sekwati Bridget Kokiya , Mongwe Pleasure Osborn , Mashao Annikie Ditshego , Adeleke Abraham A. , Nzenwata Godson Nnadozie , Adeosun Samson O. , Okonkwo George Emenike 
Published: June 2024

AbstractAlkaline roasting of a low-grade alluvial silica-based columbite bearing mineral from the Rayfield–Jos deposits (located in South Jos, Plateau state, Federal Republic of Nigeria) was conducted with specific emphasis on the evaluation of thermodynamic reactions as well as the mineral phase evolution during the extraction of Nb and Ta. An isothermal roasting procedure was investigated in order to understand the effects of different soda ash to sample mass ratios as well as the roasting temperatures on the measure or rate of the recoveries of Nb and Ta complexes. Thus, the feasibility rate of a successful alluvial columbite mineral roasting was determined to be influenced by certain optimal process conditions or optimum values of the study parameters, such as alkali to sample mass ratio and, more essentially, the roasting temperature. Therefore, the thermodynamic feasibility of the alkali-carbothermic roasting procedure was also investigated and the resulting chemical reactions were evaluated using the HSC chemistry 9.0 software. Premised on this, the results obtained as well as the thermodynamic data realized from the study demonstrated the feasibility of successful dissolutions of Nb and Ta into a pregnant leached-liquor stream (PLS), without the use of the conventional harmful, hazardous, toxic, and environmentally unfriendly hydrofluoric (HF) acid.
Mathematics teaching and teacher education against marginalisation, or towards equity, diversity and inclusion
Authors: Abtahi Yasmine , Planas Núria 
Published: June 2024

AbstractThe interrogation of often unintended practices of marginalisation has gained focus in research on mathematics teaching and mathematics teacher education throughout the last decades. In this introductory survey paper, work against marginalisation in these contexts of mathematics education is viewed in terms of work towards equity, diversity and inclusion. Based on this interpretation, we present a framework on awareness and practice of equity, diversity and inclusion in mathematics teaching and mathematics teacher education research. We then use this framework and a survey method of mapping review to identify and comment on a selection of studies. As a result, we illustrate three research moves towards equity, diversity and inclusion, in the form of interconnected themes: (1) Widening the understanding of the mathematics and the mathematics education curricula (2) Improving the practice and discussion of mathematics teaching (3) Unpacking ideologies in mathematics teaching and mathematics teacher education. We finally examine the themes and the special issue papers together to foreground commonalities regarding awareness of discriminatory discourses and practices of creating and distributing opportunities for all groups, including those historically and currently marginalised. Despite the important increase of equity-driven principles of awareness, we conclude that mathematics education research on teaching and on teacher education needs more examples of practices whose development has been proved to challenge marginalisation.
Black Women’s Sexual Well-being in the Age of Pre-Exposure Prophylaxis (PrEP): a Systematic Review of the Literature
Authors: Willie Peyton R. , Dale Sannisha K. 
Published: June 2024

Abstract
Purpose of Review
Black women’s sexual well-being is predicated upon having the autonomy, resources, and access to define, explore, and safely enjoy their sexuality and intimacy. Black cisgender and transgender women have been placed at disproportional risk for HIV due to structural and health specific inequities. Pre-exposure prophylaxis (PrEP), an effective biomedical intervention, reduces HIV transmission from sex or injection drug use by 99%, however the uptake of PrEP remains low among Black cisgender and transgender women. Using the PRISMA technique, we conducted a review of literature on Black women, cisgender and transgender, and PrEP. We used Google Scholar and PubMed to conduct the search.

Recent Findings
Our initial search garnered 2,221 sources across the two databases. However, n = 197 articles were included in this review based on the screening process and our inclusion criteria. Socio-cultural factors, provider factors, low HIV risk awareness, limited PrEP awareness and knowledge, communication, motivation, concerns about PrEP, barriers, and sexual agency, power, and pleasure may impact utilization of PrEP among Black transgender and cisgender women. However, facilitators were highlighted as well as interventions, though limited.

Summary
To adequately meet the needs of Black women and increase PrEP uptake, there is a need to address these factors that may impact utilization and develop effective interventions for Black women surrounding PrEP.
Winter is coming: Deciphering the longitudinal associations between everyday emotion regulation and depressive symptoms across the seasons
Authors: Strakosch Ana-Maria , Schulze Katrin , Miano Annemarie , Pruessner Luise , Barnow Sven 
Published: June 2024

AbstractThe dynamic interplay between emotion regulation and seasonal fluctuations in depressive symptoms remains poorly understood. Our study therefore investigated the prospective relationship between everyday emotion regulation and depressive symptoms across summer, autumn, early winter, and late winter. At each season, participants (N = 194) were asked to report their use of emotion regulation strategies (rumination, suppression, reappraisal, acceptance) using ecological momentary assessment, and to fill in online questionnaires. We observed an increase in depressive symptoms and rumination from summer to early winter, while acceptance decreased over the seasons. Participants with an overall higher use of acceptance demonstrated lower depressive symptoms. In contrast, participants showing a greater engagement in suppression, rumination, and reappraisal exhibited higher depressive symptoms, with the latter two strategies emerging as temporal precursors of symptom severity. These findings highlight the clinical importance of emotion regulation in explaining seasonal fluctuations in depressive symptoms.
Trastuzumab deruxtecan versus treatment of physician’s choice in previously treated Asian patients with HER2-low unresectable/metastatic breast cancer: subgroup analysis of the DESTINY-Breast04 study
Authors: Yamashita Toshinari , Sohn Joo Hyuk , Tokunaga Eriko , Niikura Naoki , Park Yeon Hee , Lee Keun Seok , Chae Yee Soo , Xu Binghe , Wang Xiaojia , Im Seock-Ah , Li Wei , Lu Yen-Shen , Aguilar Cecilia Orbegoso , Nishijima Soichiro , Nishiyama Yuji , Sugihara Masahiro , Modi Shanu , Tsurutani Junji 
Published: June 2024

Abstract
Background
In the global phase 3 DESTINY-Breast04 study (NCT03734029), the anti-human epidermal growth factor 2 (HER2) antibody–drug conjugate trastuzumab deruxtecan (T-DXd) demonstrated a statistically significant improvement in progression-free survival (PFS) and overall survival (OS), with manageable safety compared with treatment of physician’s choice (TPC) in patients with HER2-low metastatic breast cancer (mBC) who had received 1–2 prior lines of chemotherapy.

Methods
This subgroup analysis examined the efficacy and safety of T-DXd versus TPC in 213 patients from Asian countries and regions who were enrolled in the DESTINY-Breast04 trial and randomized to T-DXd (n = 147) or TPC (n = 66).

Results
Median PFS with T-DXd and TPC was 10.9 and 5.3 months, respectively, in Asian patients with hormone receptor-positive mBC, and 10.9 and 4.6 months, respectively, in the overall Asian population. In both populations, median OS was not reached with T-DXd and was 19.9 months with TPC. The objective response rate was higher with T-DXd versus TPC in all Asian patients. Median treatment duration was 8.4 months with T-DXd and 3.5 months with TPC. The most common grade ≥ 3 drug-related treatment-emergent adverse events in Asian patients treated with T-DXd were neutropenia (16.3%), anemia (12.9%), and leukopenia (11.6%); the incidences of neutropenia and leukopenia were higher with TPC versus T-DXd. Adjudicated drug-related interstitial lung disease or pneumonitis with T-DXd was 14.3%; the majority of events were grade 1–2.

Conclusions
T-DXd demonstrated clinically meaningful survival benefits versus TPC in Asian HER2-low mBC patients, regardless of hormone receptor status, with no new safety signals.

Clinical trial registration number
ClinicalTrials.gov, NCT03734029.
“It Takes Reflection at All Different Levels, Not Just People on the Floor”: A Qualitative Exploration of Early Childhood Professionals’ Experiences and Perspectives Towards Trauma-Informed Early Childhood Organisations
Authors: Sun Yihan , Skouteris Helen , Bowden Mitchell , Cameron Lee , Blewitt Claire 
Published: June 2024

AbstractTrauma in early childhood is a significant public health concern. Early childhood education and care (ECEC) services play a critical role in identifying and responding to children impacted by trauma. However, little is known about early childhood professionals’ experiences and needs relating to supporting trauma-impacted children. The aim of this qualitative study was to explore early childhood professionals’ experiences of working with trauma-impacted children in ECEC, the barriers to adopting trauma-informed approaches, and the organisation-wide shift that is needed to embed them. Semi-structured interviews were conducted with 22 early childhood educators, organisational leaders, and childhood trauma consultants in Victoria, Australia. Thematic analyses revealed that early childhood professionals’ perceived increasing prevalence of trauma in children attending ECEC. However, educators are generally unprepared and unsupported for this, and experience many workplace challenges leaving them feeling overwhelmed. This highlighted the need to support the professional development and well-being of early childhood educators. Meanwhile, the study identified systemic barriers impeding the implementation of trauma-informed approaches within ECEC. The findings also suggest that the collective efforts “starting from the top”, with everyone engaged, coupled with cross-sector collaboration is needed for meaningful, trauma-informed organisational change within ECEC.
Een gedragswetenschappelijk kader voor preventie in de gezondheidszorg: van probleemanalyse naar ‘deltaplan’
Authors: de Bruin Marijn , Kwakkenbos Linda , Bosman Sabien , Ruiter Rob , Jeurissen Patrick , Assendelft Pim , Verstralen Rogier , Snoek Frank J. , van Wijngaarden Jeroen 
Published: June 2024

SamenvattingGezond leven en preventie staan prominent op de beleidsagenda, ook in de gezondheidszorg. Maar op welke manier preventie het beste kan worden ingericht, blijft vooralsnog onduidelijk. In dit artikel presenteren we een gedragswetenschappelijk kader dat concreet invulling geeft aan de organisatie en inzet van preventieve gedragsinterventies in de zorg. Op basis van kwalitatief onderzoek uitgevoerd onder belangrijke stakeholders in de Nederlandse zorg, relevante literatuur en zorgmodellen in het buitenland, presenteren we de ingrediënten van een ‘deltaplan’ om dit te realiseren.
Psychological Distress in Women with Fibromyalgia: The Roles of Body Appreciation, Self-Compassion, and Self-Criticism
Authors: Levy Sigal , Ohayon Shay , Avitsur Ronit , Geller Shulamit 
Published: June 2024

Abstract
Background
While past research detected a direct link between symptoms of fibromyalgia (FM) and psychological distress, body appreciation was suggested as a viable mediator of this link. The aim of the present study was to further develop an explanatory model for the effect of FM on women’s psychological distress and identify possible protective and risk factors. Specifically, it was hypothesized that self-compassion would moderate the indirect effect of body appreciation and self-criticism on psychological distress in women with FM.

Method
This study comprised a total of 293 women, aged 20–68 (M = 34.8, SD = 12.3), of whom 146 were women with FM and 147 were heathy controls. All the women completed questionnaires regarding demographic characteristics, depression (PHQ-9), anxiety (GAD-7), self-criticism (DEQ-SC), body appreciation (BAS2), and the self-compassion scale (SCS).

Results
A moderated serial mediation model demonstrated lower body appreciation in participants with FM compared to controls. These lower levels of body appreciation, together with lower levels of self-compassion, were associated with greater self-criticism and, consequently, higher levels of psychological distress.

Conclusions
The results emphasize the role of self-compassion as a protective mechanism against psychological distress among women with FM. Future studies should further investigate the effect of self-compassion-focused interventions on patients with FM.
Assessing RNA atomistic force fields via energy landscape explorations in implicit solvent
Authors: Röder Konstantin , Pasquali Samuela 
Published: June 2024

AbstractPredicting the structure and dynamics of RNA molecules still proves challenging because of the relative scarcity of experimental RNA structures on which to train models and the very sensitive nature of RNA towards its environment. In the last decade, several atomistic force fields specifically designed for RNA have been proposed and are commonly used for simulations. However, it is not necessarily clear which force field is the most suitable for a given RNA molecule. In this contribution, we propose the use of the computational energy landscape framework to explore the energy landscape of RNA systems as it can bring complementary information to the more standard approaches of enhanced sampling simulations based on molecular dynamics. We apply the EL framework to the study of a small RNA pseudoknot, the Aquifex aeolicus tmRNA pseudoknot PK1, and we compare the results of five different RNA force fields currently available in the AMBER simulation software, in implicit solvent. With this computational approach, we can not only compare the predicted ‘native’ states for the different force fields, but the method enables us to study metastable states as well. As a result, our comparison not only looks at structural features of low energy folded structures, but provides insight into folding pathways and higher energy excited states, opening to the possibility of assessing the validity of force fields also based on kinetics and experiments providing information on metastable and unfolded states.
Antiviral Activity of Natural Compounds for Food Safety
Authors: Falcó Irene , Randazzo Walter , Sánchez Gloria 
Published: June 2024

AbstractGastroenteritis and hepatitis are the most common illnesses resulting from the consumption of food contaminated with human enteric viruses. Several natural compounds have demonstrated antiviral activity against human enteric viruses, such as human norovirus and hepatitis A virus, while little information is available for hepatitis E virus. Many in-vitro studies have evaluated the efficacy of different natural compounds against human enteric viruses or their surrogates. However, only few studies have investigated their antiviral activity in food applications. Among them, green tea extract, grape seed extract and carrageenans have been extensively investigated as antiviral natural compounds to improve food safety. Indeed, these extracts have been studied as sanitizers on food-contact surfaces, in produce washing solutions, as active fractions in antiviral food-packaging materials, and in edible coatings. The most innovative applications of these antiviral natural extracts include the development of coatings to extend the shelf life of berries or their combination with established food technologies for improved processes. This review summarizes existing knowledge in the underexplored field of natural compounds for enhancing the safety of viral-contaminated foods and underscores the research needs to be covered in the near future.
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin
Authors: Yalçın Buğdaycı Azimet , Akarca Dizakar Saadet Özen , Demirel Mürşide Ayşe , Ömeroğlu Suna , Akar Fatma , Uludağ Mecit Orhan 
Published: June 2024

Abstract
Background
It has been reported that High-Fructose (HF) consumption, considered one of the etiological factors of Metabolic Syndrome (MetS), causes changes in the gut microbiota and metabolic disorders. There is limited knowledge on the effects of metformin in HF-induced intestinal irregularities in male and female rats with MetS.

Objectives
In this study, we investigated the sex-dependent effects of metformin treatment on the gut microbiota, intestinal Tight Junction (TJ) proteins, and inflammation parameters in HF-induced MetS.

Methods
Fructose was given to the male and female rats as a 20% solution in drinking water for 15 weeks. Metformin (200 mg/kg) was administered by gastric tube once a day during the final seven weeks. Biochemical, histopathological, immunohistochemical, and bioinformatics analyses were performed. Differences were considered statistically significant at p < 0.05.

Results
The metformin treatment in fructose-fed rats promoted glucose, insulin, Homeostasis Model Assessment of Insulin Resistance Index (HOMA-IR), and Triglyceride (TG) values in both sexes. The inflammation score was significantly decreased with metformin treatment in fructose-fed male and female rats (p < 0.05). Moreover, metformin treatment significantly decreased Interleukin-1 Beta (IL-1β) and Tumor Necrosis Factor-Alpha (TNF-α) in ileum tissue from fructose-fed males (p < 0.05). Intestinal immunoreactivity of Occludin and Claudin-1 was increased with metformin treatment in fructose-fed female rats. HF and metformin treatment changed the gut microbial composition. Firmicutes/Bacteroidetes (F/B) ratio increased with HF in females. In the disease group, Bifidobacterium pseudolongum; in the treatment group, Lactobacillus helveticus and Lactobacillus reuteri are the prominent species in both sexes. When the male and female groups were compared, Akkermansia muciniphila was prominent in the male treatment group.

Conclusion
In conclusion, metformin treatment promoted biochemical parameters in both sexes of fructose-fed rats. Metformin showed a sex-dependent effect on inflammation parameters, permeability factors, and gut microbiota. Metformin has partly modulatory effects on fructose-induced intestinal changes.

Graphical Abstract
A note on the application of the RVT method to general classes of single-species population models formulated by random differential equations
Authors: Rodríguez Francisco , Lachachi Fatima Z. , Medjahdi Ikram , Castro M. Ángeles , Cortés Juan Carlos 
Published: June 2024

AbstractThe Random Variable Transformation (RVT) technique has been applied in recent years to analyze a wide variety of dynamic models formulated via random differential equations. The applicability of this technique has usually been focused on problems where an explicit solution of the underlying deterministic problem is available. This fact limits the usefulness of the RVT method. This note aims to point out that the RVT technique can be successfully applied without this requirement by showing a wider range of potential applications including very general classes of single-species models.
Multidisciplinary Management of Pediatric Chronic Rhinosinusitis with Nasal Polyposis
Authors: Oh Eugene , Miller Jessa E. , Lee Jivianne T. 
Published: June 2024

Abstract
Purpose of review
This review explores the comprehensive management and treatment strategies for pediatric chronic rhinosinusitis with nasal polyps (CRSwNP). It addresses questions regarding the efficacy and safety of both current treatments and emerging therapies. Additionally, this paper examines the diagnostic challenges in pediatric CRSwNP, particularly its distinct presentations and characteristics compared to those in adults.

Recent findings
Current research highlights various approaches for treating pediatric CRSwNP. Intranasal corticosteroids are found to be effective in managing symptoms, while oral corticosteroids are used to manage severe cases. Antibiotic therapy is recommended for acute exacerbations of CRSwNP when a bacterial cause is suspected. Surgical interventions such as adenoidectomy and endoscopic sinus surgery are considered when medical therapy fails. Emerging biologic therapies show promise but require further investigation regarding safety and cost-effectiveness in the pediatric population.

Summary
The findings suggest that a multimodal approach is essential for treating pediatric CRSwNP. Future research should aim to develop targeted therapies and refine treatment guidelines specifically for the pediatric population.
From the Lab to the Wild: Examining Generalizability of Video-based Mind Wandering Detection
Authors: Bühler Babette , Bozkir Efe , Goldberg Patricia , Sümer Ömer , D’Mello Sidney , Gerjets Peter , Trautwein Ulrich , Kasneci Enkelejda 
Published: June 2024

AbstractStudent’s shift of attention away from a current learning task to task-unrelated thought, also called mind wandering, occurs about 30% of the time spent on education-related activities. Its frequent occurrence has a negative effect on learning outcomes across learning tasks. Automated detection of mind wandering might offer an opportunity to assess the attentional state continuously and non-intrusively over time and hence enable large-scale research on learning materials and responding to inattention with targeted interventions. To achieve this, an accessible detection approach that performs well for various systems and settings is required. In this work, we explore a new, generalizable approach to video-based mind wandering detection that can be transferred to naturalistic settings across learning tasks. Therefore, we leverage two datasets, consisting of facial videos during reading in the lab (N = 135) and lecture viewing in-the-wild (N = 15). When predicting mind wandering, deep neural networks (DNN) and long short-term memory networks (LSTMs) achieve F$$_{1}$$

1

scores of 0.44 (AUC-PR = 0.40) and 0.459 (AUC-PR = 0.39), above chance level, with latent features based on transfer-learning on the lab data. When exploring generalizability by training on the lab dataset and predicting on the in-the-wild dataset, BiLSTMs on latent features perform comparably to the state-of-the-art with an F$$_{1}$$

1

score of 0.352 (AUC-PR = 0.26). Moreover, we investigate the fairness of predictive models across gender and show based on post-hoc explainability methods that employed latent features mainly encode information on eye and mouth areas. We discuss the benefits of generalizability and possible applications.