bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical outcomes for patients with soft tissue sarcoma of the hand
Authors: Puhaindran Mark E. , Rohde Rachel S. , Chou Joanne , Morris Carol D. , Athanasian Edward A. 
Published: August 2010

AbstractBACKGROUND:In an earlier report from the current study center regarding surgical treatment for patients with soft tissue sarcoma (STS) of the hand, it was concluded that repeat resection or amputation improves outcomes. Since then, the authors have aggressively sought to achieve negative resection margins, using standard or modified amputations when needed, and performing repeat resections to negative surgical margins when they were not achieved at the time of initial surgery. The current review was conducted to determine whether this approach resulted in better outcomes.METHODS:A retrospective review of 53 patients with STS of the hand who were treated between 1996 and 2005 was performed. Recurrence‐free survival (RFS) and functional outcome of hand‐preserving procedures were assessed according to the Musculoskeletal Tumor Society (MSTS) system.RESULTS:The median RFS was not reached at the time of last follow‐up. Of 53 patients, 6 (11%) had positive microscopic resection margins. Three patients underwent repeat resection to negative surgical margins, whereas another 3 patients did not. All 3 patients with positive microscopic surgical margins that were not re‐excised developed local disease recurrence; 2 patients also developed distant metastases. Two of the 50 patients with negative resection margins developed distant metastases. All 5 patients who developed local and/or distant disease recurrence had deep tumors. The median MSTS score was 29 (interquartile range, 27‐30). Patients who underwent more extensive resections, such as double ray amputations, had lower MSTS scores.CONCLUSIONS:Suboptimal biopsies and positive resection margins are associated with local and distant disease recurrence in patients with STS. The results of the current study suggest that aggressive surgical treatment can result in better clinical outcomes, and underscore that care must be taken when planning biopsies of hand tumors. Cancer 2011. © 2010 American Cancer Society.
e‐Science Central for CARMEN: science as a service
Authors: Watson Paul , Hiden Hugo , Woodman Simon 
Published: August 2010

AbstractScientists face many severe challenges in extracting value from the increasingly large volumes of data they generate. In this paper we describe the requirements we have derived from working across a wide range of e‐science projects. In particular, the CARMEN neuroinformatics project has exposed a range of challenges due to a need to analyse and share large volumes of data. We have identified the four key activities required by scientists with whom we work, and designed an integrated system—e‐Science Central—to provide them. This exploits three emerging technologies: software as a service to avoid the need for users to deploy and maintain any of their own software; social networking to allow users to collaborate by sharing data, services and workflows in a controlled manner and Cloud computing to provide scalable compute resources. The system can not only be used through any web browser, but also provides an API so that applications can build on the core functionality. We describe the requirements, and the design that flows from them. This includes data storage with in‐built versioning and signing, an in‐browser workflow editor and a job scheduling system that allows workflows to be run both on local ‘private’ clouds and the Microsoft Azure Cloud. Copyright © 2010 John Wiley & Sons, Ltd.
The scalable process topology interface of MPI 2.2
Authors: Hoefler Torsten , Rabenseifner Rolf , Ritzdorf Hubert , de Supinski Bronis R. , Thakur Rajeev , Träff Jesper Larsson 
Published: August 2010

AbstractThe Message‐passing Interface (MPI) standard provides basic means for adaptations of the mapping of MPI process ranks to processing elements to better match the communication characteristics of applications to the capabilities of the underlying systems. The MPI process topology mechanism enables the MPI implementation to rerank processes by creating a new communicator that reflects user‐supplied information about the application communication pattern. With the newly released MPI 2.2 version of the MPI standard, the process topology mechanism has been enhanced with new interfaces for scalable and informative user‐specification of communication patterns. Applications with relatively static communication patterns are encouraged to take advantage of the mechanism whenever convenient by specifying their communication pattern to the MPI library. Reference implementations of the new mechanism can be expected to be readily available (and come at essentially no cost), but non‐trivial implementations pose challenging problems for the MPI implementer. This paper is first and foremost addressed to application programmers wanting to use the new process topology interfaces. It explains the use and the motivation for the enhanced interfaces and the advantages gained even with a straightforward implementation. For the MPI implementer, the paper summarizes the main issues in the efficient implementation of the interface and explains the optimization problems that need to be (approximately) solved by a good MPI library. Copyright © 2010 John Wiley & Sons, Ltd.
On the Origin of the Visible‐Light Activity of Titanium Dioxide Doped with Carbonate Species
Authors: Tian FengHui , Liu ChengBu , Zhang Dongju , Fu Aiping , Duan Yunbo , Yuan Shuping , Yu Jimmy C. 
Published: August 2010

AbstractPlane‐wave‐based pseudopotential density functional theory (DFT) calculations are used to elucidate the origin of the high photocatalytic efficiency of carbonate‐doped TiO2. Two geometrically possible doping positions are considered, including interstitial and substitutional carbon atoms on Ti sites. From the optical absorption properties calculations, we believe that the formation of carbonates after doping with interstitial carbon atoms is crucial, whereas the contribution from the cationic doping on Ti sites is negligible. The carbonate species doped TiO2 exhibits excellent absorption in the visible‐light region of 400–800 nm, in good agreement with experimental observations. Electronic structure analysis shows that the carbonate species introduce an impurity state from Ti 3d below the conduction band. Excitations from the impurity state to the conduction band may be responsible for the high visible‐light activity of the carbon doped TiO2 materials.
What is narrative therapy and what is it not? The usefulness of Q methodology to explore accounts of White and Epston's (1990) approach to narrative therapy
Authors: Wallis Jennifer , Burns Jan , Capdevila Rose 
Published: August 2010

AbstractObjective. ‘What is narrative therapy and how do you do it?’ is a question that is repeatedly asked of narrative therapy, with little consistent response. This study aimed to explore and distil out the ‘common themes’ of practitioner definitions of White and Epston's approach to narrative therapy.Design. This was an Internet‐based study involving current UK practitioners of this type of narrative therapy using a unique combination of a Delphi Panel and Q methodology.Method. A group of experienced practitioners were recruited into the Delphi Poll and were asked two questions about what narrative therapy is and is not, and what techniques are and are not employed. These data combined with other information formed the statements of a Q‐sort that was then administered to a wider range of narrative practitioners.Findings. The Delphi Panel agreed on a number of key points relating to the theory, politics and practice of narrative therapy. The Q‐sort produced eight distinct accounts of narrative therapy and a number of dimensions along which these different positions could be distinguished. These included narrative therapy as a political stance and integration with other approaches.Conclusions. For any therapeutic model to demonstrate its efficacy and attract proponents, an accepted definition of its components and practice should preferably be established. This study has provided some data for the UK application of White and Epston's narrative therapy, which may then assist in forming a firmer base for further research and practice. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Narrative therapy and how it is carried out remain unclearly defined, which limits studies of the efficacy of this approach.• Experienced practitioners of narrative therapy were able to identify a set of core concepts, values and techniques over which there was some consensus.• This study also identified the different ‘positionings’ of narrative therapy that have contributed to its opacity and have highlighted the diversity in therapist practice.
Separation of glucose and fructose by freezing crystallization
Authors: Silva A. T. C. R. , Martinez K. C. L. , Brito A. B. N. , Giulietti M. 
Published: August 2010

AbstractThis work comprises the implementation of a methodology for the study of an industrial crystallization process by freezing and cooling to be applied in the separation of sugars with industrial relevance (glucose and fructose). The main interest is the production of fructose. This sugar is obtained by sucrose hydrolysis in acidic solutions, which yields an equimolar mixture of glucose and fructose. The developed separation process is based on the solubility difference between the sugars. Experiments were carried out in a jacketed glass crystallizer where the solution coming from the sucrose acid inversion was submitted to a slow cooling. Since glucose has lower solubility than fructose, it crystallizes in the bulk as the temperature is lowered, thus it can be removed from the solution by fliltration or centrifugation. Best fructose‐glucose separation was achieved for a total sugar concentration of 50 wt%. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Influence of period‐doubling bifurcations in the appearance of border collisions for a ZAD‐strategy‐controlled buck converter
Authors: D'Amico M. B. , Angulo F. , Olivar G. , Paolini E. E. , Moiola J. L. 
Published: August 2010

SUMMARYThe first period‐doubling bifurcation of a dc–dc buck converter controlled by a zero‐average dynamic strategy is studied in detail. Owing to the saturation of the duty cycle, this bifurcation is followed by a border‐collision bifurcation, which is the main mechanism to introduce instability and chaos in the circuit. The multiparameter analysis presented here leads to a complete knowledge of the relatioship between these two bifurcations. The results are obtained by using a frequency‐domain approach for the study of period‐two oscillations in maps. Copyright © 2010 John Wiley & Sons, Ltd.
Mass Analysis of Growth of Al2O3 Thin Films from Low‐Temperature Atomic Layer Deposition on Woven Cotton
Authors: Hojo Daisuke , Adschiri Tadafumi 
Published: August 2010

AbstractAtomic layer deposition (ALD) at 100 °C provides a conformal coating on woven cotton with a tortuous and complex surfaces. The woven structures are completely preserved and replicated with thin coating of Al2O3, even after removing the cotton templates. The replicated woven structures enable direct mass analysis of the cotton coating. Quantitative analysis reveals that the self‐limiting reaction of ALD is ensured, even on tortuous cotton surfaces, except for early growth cycles. This unique feature of ALD assures conformal coating onto three‐dimensional (3D) networks of cotton. The results demonstrate the possibility of a non‐local methodology for evaluating the thickness of a coating on 3D objects at various stages of growth.
An irregular frequency reuse scheme for cellular OFDMA systems
Authors: Rim Minjoong 
Published: August 2010

AbstractWhile conventional frequency reuse techniques need to allocate mutually exclusive frequency resources to adjacent cells, this paper proposes a technique for OFDMA systems to use pseudo‐random subchannel allocation patterns based on the preamble number. Although sophisticated cell planning is not required for the proposed technique, irregular frequency patterns can allow efficient interference avoidance and high data throughput. Copyright © 2010 John Wiley & Sons, Ltd.
Zirconocene Functional Group Chemistry: Photochemical [4+4] Cycloaddition of Isoprenyl Sidechains to the Bent Metallocene Framework
Authors: Greger Ingo , Kehr Gerald , Erker Gerhard 
Published: August 2010

AbstractThe 4‐isoprenyl‐ and 1‐isoprenylcyclopentadienides 6a and 6b were prepared by means of a fulvene route involving a subsequent deprotonation reaction using potassium hexamethyldisilylamide. Transmetallation to zirconium or hafnium gave the respective bis(4‐isoprenyl‐Cp)MCl2 and bis(1‐isoprenyl‐Cp)MCl2 complexes 7a,b and 8a,b, respectively. Upon photolysis, the (4‐isoprenyl‐Cp)2ZrCl2 and ‐HfCl2 complexes 7a, 8a underwent rapid intramolecular [4+4] cycloaddition reactions to yield the cyclooctadienylene‐bridged ansa‐metallocenes 9a, 10a in high yields.
Various Synthetic Methods for One‐Dimensional Semiconductor Nanowires/Nanorods and Their Applications in Photovoltaic Devices
Authors: Chun Jinyoung , Lee Jinwoo 
Published: August 2010

AbstractIn this microreview, the recent progress on various synthetic methods for 1D semiconductor nanowires is summarized. The colloidal synthetic method has been popularly employed to prepare various semiconductor nanorods/nanowires such as ZnS and TiO2. The vapor–liquid–solid (VLS) synthetic method has been used to fabricate Si and ZnO nanowires. For the growth of semiconductor nanowires by the VLS method, metals that can form a eutectic mixture with a target material have been used as catalysts. After the first report on the synthesis of crystalline III–V semiconductor nanowires by the solution–liquid–solid (SLS) method, various kinds ofIII–V and II–VI semiconductor nanowires have been synthesized by the SLS method. Various types of templates, including anodic aluminum oxide (AAO), sacrificial nanowire templates, and self‐assembled surfactants, have been employed to fabricate 1D semiconductor nanowires that resemble the shape of the template employed. Using 1D semiconductor nanowires, high‐performance photovoltaic cells can be fabricated due to facile electron transport within nanowires.
Design of a Vitamin B1‐Selective Electrode Based on an Ion‐Pair and Its Application to Pharmaceutical Analysis
Authors: Antal Iryna , Kormosh Zholt , Bazel Yaroslav , Lysenko Svitlana , Kormosh Natalya 
Published: August 2010

AbstractVitamin B1‐selective electrodes with PVC membrane were developed that contain ion associates of vitamin B1 with an inorganic anion, BiI4−, and an organic anion, brilliant yellow, as electrode‐active substances. The linearity ranges of the electrode function are 1.0×10−5–1.0×10−2 and 1.0×10−4–1.0×10−2 M, the electrode function slopes are 33.0±1.0 and 33.1±1.1 mV decade−1, the detection limits are 5.5×10−6 and 8.3×10−5 M for BiI4− and brilliant yellow respectively. The working range of pH is 5–12. The efficiency of the use of electrodes for the vitamin B1 content control in multivitamin pharmaceutical preparations was shown by direct potentiometry and potentiometric titration methods.
Electroanalysis of Norepinephrine at Bare Gold Electrode Pure and Modified with Gold Nanoparticles and S‐Functionalized Self‐Assembled Layers in Aqueous Solution. Part II
Authors: Łuczak Teresa 
Published: August 2010

AbstractGold electrodes modified with S‐containing compounds and gold were used for determination of norepinephrine (NEP) in aqueous solution. A linear relationship between norepinephrine concentration and current response was obtained in the range of 0.1 µM to 600 µM with the detection limit ≤0.090 µM for the electrodes modified at 2D template and in the range of 0.1 µM to 700 µM with the detection limit ≤0.075 µM for the electrodes modified at 3D template. The results have shown that modified electrodes could clearly resolve the oxidation peaks of norepinephrine, ascorbic (AA) and uric acid (UA) with peak‐to‐peak separation enabling determination of NEP, AA and UA in the presence of each other.
Electrochemical Behavior of Herbal Antitumor Drug Aloe‐Emodin at Carbon‐Coated Nickel Magnetic Nanoparticles Modified Glassy Carbon Electrode
Authors: Bian Chunli , Zhang Lin , Xiong Huayu , Zhang Xiuhua , Wang Shengfu 
Published: August 2010

AbstractThe electrochemical behavior of aloe‐emodin (AE), an important herbal antitumor drug, was investigated at a carbon‐coated nickel magnetic nanoparticles modified glassy carbon electrode (CNN/GCE). A couple of well‐defined redox peaks was obtained. Some electrochemical parameters of AE at a CNN/GCE, such as the charge number, exchange current density, standard heterogeneous rate constant, were measured. The square wave voltammetry (SWV) response of AE was linear with the concentration over two concentration intervals viz. 6.24×10−9−1.13×10−6 M and 1.13×10−6−1.23×10−5 M, with a detection limit of 2.08 nM. A fast, simple and sensitive detection and analysis of AE was developed.
Quantification of Quercetin Using Glassy Carbon Electrodes Modified with Multiwalled Carbon Nanotubes Dispersed in Polyethylenimine and Polyacrylic Acid
Authors: Gutiérrez Fabiana , Ortega Gabriela , Cabrera José Luis , Rubianes María D. , Rivas Gustavo A. 
Published: August 2010

AbstractThis work reports the highly sensitive detection of quercetin using glassy carbon electrodes modified with multiwall carbon nanotubes (MWCNT) dispersed in polyethylenimine and poly(acrylic acid). The adsorptive stripping with square wave voltammetric transduction allowed the detection of 7.5 nM quercetin after 1.0 min accumulation at open circuit potential. The amperometric detection at 0.150 V is reported as an easier and simpler alternative to determine quercetin, with detection limits of 0.2 µM. The careful selection of the working conditions also made possible the detection of submicromolar levels of quercetin in the presence of excess of rutin. The proposed methodology was successfully used to quantify quercetin in onion samples.
Polystyrene spheres coated with gold nanoparticles for detection of DNA
Authors: Li Shaohua , Xia Yuetong , Zhang Jianping , Han Jianhua , Jiang Long 
Published: August 2010

AbstractA novel method has been developed here utilizing gold‐modified polystyrene spheres (PS@Au) as carriers for the investigation of DNA hybridization. The immobilization ability of DNA probes on the PS@Au was investigated by a quartz crystal microbalance (QCM). More gold nanoparticles (AuNPs) were conjugated to the QCM surface in the form of PS@Au as compared with the AuNPs alone. The influence of PS, AuNPs population and size on the DNA probe fixation, and hybridization has been investigated. The results show that more AuNPs were achievable onto the QCM surface and could greatly increase the immobilization amount further hybridization amount of DNA. There was an optimal surface curvature for the probe DNA absorption. The curvature about 12 nm was more suited to the adsorption of probe DNA which could lead to the detection limit further down to 10−12 M. These results demonstrate that the introduction of PS@Au, with polystyrene spheres as the medium between the QCM surface and the AuNPs, could achieve modified QCM surfaces and increase its detection ability for a better DNA assay and a novel platform for the fabrication of DNA sensors.
Application of Sharpless asymmetric epoxidation on the preparation of the optically active flavours 3‐methylthiohexanal and 5(6)‐butyl‐1,4‐dioxan‐2‐one
Authors: Tian Hong‐yu , Sun Bao‐guo , Tang Li‐wei , Ye Hong‐lin 
Published: August 2010

AbstractOptically active 2,3‐epoxyhexanol obtained from Sharpless asymmetric epoxidation (AE) was regioselectively reduced to 1,3‐hexandiol or 1,2‐hexandiol. 1,3‐Hexandiol was converted to 3‐mesyloxyhexyl acetate. The following reaction with CH3SK gave 3‐methylthiohexanol, which was oxidized through Swern oxidation to produce 3‐methylthiohexanal. 5‐ and 6‐Butyl‐1,4‐dioxan‐2‐one were formed concurrently by the reaction of 1,2‐hexandiol with 2‐bromoacetic chloride and the ratio of 5‐butyl isomer to 6‐butyl isomer was about 1:4. The enantiomeric excess values of both enantiomers of 3‐methylthiohexanal and 5(6)‐butyl‐1,4‐dioxan‐2‐one were about 90%, which were very close to those of 2,3‐epoxyhexanol (about 94% ee). No obvious racemization occurred during the transformation from the Sharpless AE products to the final products.
Identification of the causes of an allergic reaction to a fragranced consumer product
Authors: Cadby Peter , Ellis Graham , Hall Barbara , Surot Carol , Vey Matthias 
Published: August 2010

AbstractIdentification of substances in consumer products (more particularly fragrance allergens in cosmetics) that are responsible for cases of contact dermatitis is of key importance for the patient and also for industry so that appropriate risk management measures can be applied. This is best done by a close collaboration between the dermatologist, the manufacturer of the consumer (cosmetic) product and the fragrance supplier. This paper describes a recommended practice that has been successfully applied for many years to achieve this goal. Copyright © 2010 John Wiley & Sons, Ltd.
Identification of a functional hepatocyte nuclear factor 4 binding site in the neutral ceramidase promoter
Authors: Maltesen Henrik R. , Troelsen Jesper T. , Olsen Jørgen 
Published: August 2010

AbstractThe brush border membrane of the differentiated small intestinal epithelial cell is studded with membrane bound hydrolytic ectoenzymes involved in digestion. Previous studies of the regulation of genes encoding brush border enzymes have especially implicated the transcription factors hepatocyte nuclear factor HNF‐1 and Cdx2. Recent genome‐wide studies have, however, also identified HNF‐4α as a transcription factor with a high number of target genes in the differentiated small intestinal epithelial cell. The Asah2 gene encodes neutral ceramidase, which is a hydrolytic brush border enzyme involved in ceramide digestion. It was the purpose of the present work to experimentally verify the functional importance of a HNF‐4α binding site predicted by bioinformatic analysis to be present in the Asah2 promoter. Using supershift analysis, HNF‐4α overexpression, and HNF‐4α knockdown experiments it was confirmed that the predicted HNF‐4α binding site identified in the Asah2 promoter is functional. The results support the hypothesis that HNF‐4α might be important for intestinal glycolipid metabolism. J. Cell. Biochem. 111: 1330–1336, 2010. © 2010 Wiley‐Liss, Inc.