bluuebunny/crossref_metadata_2025_split huggingface dataset:
Discontinua urbani. Dispositio e città nel Novecento
Authors: Francesco Costanzo  
Published: June 2024

Il contributo tende a mettere in luce i rapporti tra l’aspirazione novecentesca al discontinua urbani e la dispositio. Sulla base di una premessa centrata su tre questioni rilevanti (valore del centro, relazione ordine discontinuo/identità del manufatto, modalità di trasferimento delle condizioni di contesto nella spazialità discontinua), il testo approfondisce i contenuti del principio eteronomo e del metodo selettivo che hanno caratterizzato il contributo di alcuni maestri della scuola italiana nella seconda metà del secolo scorso.
Progetto e/è ricerca. Sulla valutazione del progetto come prodotto di ricerca scientifica
Authors: Enrico Prandi  
Published: June 2024

Recensione del testo: Autore: Roberta Amirante Titolo: Il progetto come prodotto di ricerca Sottotitolo: Un'ipotesi Lingua del testo: italiano Editore: LetteraVentidue, Siracusa Caratteristiche: formato 12x16,5 cm, 128 pagine, brossura, b/n ISBN: 9788862422833 Anno: Giugno 2018
Zissis Kotionis. Il testo come assemblage.
Authors: Fabiano Micocci  
Published: June 2024

I testi del prof. Zissis Kotionis, architetto e artista greco, dichiarano due urgenze: da una parte la necessità della speculazione teorica come supporto per la produzione architettonica, e dall'altra l'esigenza della scrittura come elemento irrinunciabile di ricerca progettuale. Si afferma dunque la centralità del testo come progetto. La struttura narrativa di questi testi è impostata su collezioni di frammenti assemblati tra loro, che piuttosto che codici indicano una molteplicità di possibilità operative. Non importa se si tratta di testi di critica dell'architettura, teoria o poesie: la struttura si ripete e si aggiorna, attribuendo nuovi significati al processo di assemblage testuale.
Pensare al futuro
Authors: Franco Purini  
Published: June 2024

Recensione al libro Autore: Marcello Sèstito Titolo: Corpo e Architettura o de humani fabrica Lingua: italiano Editore: Rubbettino Caratteristiche: formato 24x32 cm, brossura, colori ISBN: 9788849852110 Anno: 2017
Da Mies a Zumthor. Un’idea di Museo: dalle muse alla fabbrica.
Authors: Renato Capozzi  
Published: June 2024

The paper aims to investigate the concept of museum that Mies van der Rohe offers - starting from the German Pavilionat the Universal Exhibition in Brussels in 1935, unfortunately not built, passing through a Museum for a small cityin 1943 and ending with the Neue Nationalgalerie in Berlin in 1968 - and to show how this typological-spatial principle has to a large extent determined and made possible a series of influences and relative declinations in the contemporary conception of the museum as a free and available “space of the artwork | work space”, as a place of meeting and communication assumed and as a “Making workshop | craft factory” exemplified by Peter Zumthor's recent Werkraumat Andelsbuch in 2013. Il paper vuole indagare la concezione di museo che Mies mette a punto – a partire dal progetto per il Padiglione tedesco alla Esposizione Universale di Bruxelles del 1935, passando per un Museo per una piccola città del 1943 per finire con la Neue Nationalgalerie di Berlino del 1968 – e far vedere, anche attraverso il ridisegno critico, come tale principio tipologico-spaziale abbia determinato notevoli influenze nella concezione contemporanea di museo come libero e disponibile “spazio dell’opera | spazio del lavoro”, luogo di incontro e comunicazione assunto come “laboratorio | fabbrica del fare” esemplarizzato dalla Werkraum del 2013 di Peter Zumthor ad Andelsbuch.
Takis Zenetos’s City and House of the Future: Resynchronising Quotidian Life
Authors: Marianna Charitonidou  
Published: June 2024

The article focuses on the analysis of the work of architects as Takis Zenetos, Yona Friedman, and Archigram and examines how he conceptualized the reinvention of the relationship between the living units and the home-office conditions. It pays special attention to his concern about incorporating the new conceptions of “tele-work”, “tele-communication”, and “tele-education” in architecture and urban design. It departs from the hypothesis that several of the core ideas of the experimentations of Zenetos concerning the living units in the city of the future could be incorporated in the design of architectural and urban projects aiming to contribute to pandemic preparedness. Particular emphasis is placed on Zenetos’ endeavour, in his “Electronic Urbanism” to take into account the complexity of the psychological and physiological needs of the citizens.
Luigi Ghirri e Niente di antico sotto il sole.
Authors: Paolo Barbaro  
Published: June 2024

Recensione del libro Autore: Luigi Ghirri Titolo: Niente di antico sotto il sole. Scritti e interviste 1973-1991 Lingua: italiano Editore: Quodlibet Caratteristiche: 14x21cm, 354 pagine, brossura, b/n ISBN: 978-8822906144 Anno: 2021
Lina Bo Bardi. L’invenzione della felicità/ Lina Bo Bardi. The creation of happiness
Authors: Caterina Lisini  
Published: June 2024

«Lo scrivere non mi interessa», dice con sobria franchezza Lina Bo Bardi a Francesco Tentori, «so perfettamente di saper scrivere bene. I miei maestri sono Stendhal e Majakowskij. Il primo mi ha insegnato la concisione, quando annotò di aver imparato a scrivere dai direttori del catasto edilizio francese e dagli estensori degli articoli del Codice Civile. Il secondo, invece, mi ha insegnato il ritmo, la fantasia del reale». Anche il disegno, nella Bo Bardi, sembra vivere di una analoga doppia anima, fino a una multiformità di valenze straordinariamente feconde. Non solo, o non tanto, disegni di architettura, disegni tecnici funzionali al progetto, all’esecutivo, al cantiere. Ma neppure disegni semplicemente ideativi, schizzi di studio, disegni di ricerca teorica o d’espressione. E neppure, ancora, disegni di viaggio, di impressione, di fantasia. I suoi disegni, dal tratto a volte un po’ naïf, altre volte precisi e costruttivi, variati in tante tecniche, dallo schizzo, all’acquerello, al disegno a china, al collage, e spazianti su temi e scale estremamente variegati, semplici oggetti d’uso, mobili, gioielli, vestiti, singole abitazioni popolari, edifici e complessi edilizi, allestimenti espositivi, scenografie teatrali, nel loro insieme sembrano tutti segnati da un apparente, dichiarato ossimoro: «la fantasia del reale». Una visione sempre tenacemente aderente alla realtà, una realtà che per Lina, da quando approda nel 1946 a Rio de Janeiro, città principe dello spirito brasiliano, è intrisa di speranza e di vitalità, a cui Lina risponde con una creatività spontanea e impetuosa, – «furiosa» la definisce Semerani–, inseparabile dalla esperienza del corpo e dalla fisicità del reale, esercitata nel plasmare progetti rigorosi e subito nel contaminarli con una festosa e ironica invenzione della felicità. «Todos juntos», vuole Lina i destinatari del suo Sesc Pompeia, «giovani, bambini, terza età, tutti uniti nel piacere di ritrovarsi insieme, nel danzare, cantare». C’è nei disegni della Bo Bardi, e a ben vedere in tutta la sua opera e personalità, una conflittualità, o meglio una fruttuosa compresenza, tra una propensione razionale da un lato, che ben si sposa con la sua formazione eurocentrica, e una vena surrealista dall’altro, che si fonde con l’adesione istintiva alla cultura popolare, ai miti, ai riti ancestrali della tradizione locale: quell’«incanto», come dirà, provato immediatamente al suo arrivo a Rio, «una speranza reale quasi quotidiana, non metafisica, nella semplicità delle soluzioni architettoniche, nei ciao umani, cose sconosciute per una generazione che arrivava da molto lontano». Se il disegno può considerarsi una specie di autobiografia dell’architetto, il saggio si propone di analizzare da vicino i multiformi disegni di Lina Bo Bardi, le loro tecniche tanto quanto i contenuti e i modi di rappresentazione, affrontati come testo indiziario della sua straordinaria personalità.
Teoria e progetto. La continuità di un confronto
Authors: Marvin Cukaj  
Published: June 2024

Recensione al testo Autore: Raffaella Neri Titolo: Il filo di un pensiero Sottotitolo: scritti, appunti, lezioni Lingua del testo: italiano Editore: CLEAN edizioni Caratteristiche: formato 16x24 cm, 202 pagine, brossura, bianco e nero ISBN: 9788884976765 Anno: 2020
Case della Salute e Case di Comunità in Italia: una prima ricognizione
Authors: Simbari Alessia 
Published: June 2024

Questo articolo affronta il tema delle "Case della Salute," tipologia sostanzialmente nuova per la quale manca una consolidata letteratura scientifica nel settore dell’architettura nell’accezione compositiva architettonica e urbana. L'emergenza sanitaria causata dal virus SARS-CoV-2 ha evidenziato in particolare la vulnerabilità delle strutture sanitarie di base, conducendo all'istituzione, all’interno del Piano Nazionale di Ripresa e Resilienza (DM n. 77/2022), di nuove "Case della Comunità". In questo quadro, pur disponendo di analogie tematiche e tipologiche, come ospedali e centri sanitari distrettuali, pare opportuna una ricognizione di quanto è stato realizzato in tempi recenti in termini di strutture decentrate e già in buona parte corrispondenti all’evoluzione comunitaria della Casa della Salute. Questo articolo fornisce quindi esempi di "Case della Salute" e "Case di Comunità" già realizzate o in fase di progettazione nel contesto italiano, focalizzandosi in particolare sull'analisi degli esiti in termini di carattere tipo-morfologico delle architetture realizzate. Tuttavia, è necessario sottolineare che la documentazione dei progetti architettonici finanziati dal PNRR allo stato attuale, disponibili pubblicamente, risulta essere piuttosto carente e quindi suscettibile di progressivi aggiornamenti.
Effective palliation of refractory ascites in cirrhosis is challenging
Authors: Abbott Jane , Verma Sumita , Saksena Sushma 
Published: June 2024

Background: Palliative care is often suboptimal for patients with end-stage liver disease (ESLD). Ascites remains the most common complication in ESLD. Though long-term abdominal drains (LTAD) are commonly used in refractory malignant ascites, the standard care for ESLD is hospital drainage (large volume paracentesis (LVP)). There is an ongoing National Institute for Health and Care Research (NIHR) funded trial (REDUCe 2 Study) (ISRCTN269936824) comparing palliative LTAD to LVP in ESLD. This 35-site trial is being conducted in England, Scotland and Wales. Aim: To understand the views and experience of healthcare professionals (HCP) on the use of palliative LTAD in ESLD. Methods: An electronic survey comprised of seven questions with fixed quantitative options and three exploratory questions was used between August–December 2019. The survey was distributed electronically via the British Association for Study of Liver newsletter and to relevant hospital departments in Southeast England and Northeast London. An email reminder was sent at 4 and 8 weeks after the initial invitation to the survey. Results: There were 211 respondents (hepatologists (36.5%), specialist nurses (24.6%), gastroenterologists (16.6%), trainees (17%) and others (5.2%)). All respondents had access to LVP, 86% to a transjugular intrahepatic portosystemic shunt procedure for patients, 67% to LTADs and 10% to other options, such as the automated low-flow ascites (ALFA) pump. The majority of respondents to the survey (68%) reported their experience of using LTAD. Almost all respondents (91%) were willing to consider LTAD in ESLD. However, the main deterrents of this were the perceived risk of infection (90%), followed by LTAD management in community (57%). Some 51% of those with prior experience of using LTAD reported clinical complications for patients (including bleeding, infection and renal impairment), 41% reported technical issues and 35% inadequate community support. Conclusions: Almost all HCPs are willing to consider palliative LTAD in refractory ascites due to ESLD, but the main deterrents are the perceived infection risk and lack of published data to guide community management. The REDUCe 2 trial will clarify if these concerns are real and provide conclusive evidence on role, if any, of palliative LTADs in this vulnerable and under researched cohort with ESLD.
Challenges in clinical diagnosis of Clade I Mpox: Highlighting the need for enhanced diagnostic approaches
Authors: Bourner Josephine , Garcia-Gallo Esteban , Mbrenga Festus , Boum Yap , Nakouné Emmanuel , Paterson Amy , Jones Benjamin , Olliaro Piero , Rojek Amanda 
Published: June 2024

Background
Due to limited diagnostic capacity and availability of point-of-care tests, diagnosis of Clade I mpox in the geographical regions most affected is usually on clinical grounds. This may be complicated due to the similarity between mpox and varicella (chickenpox) lesions. Visual assessment of lesions is also used for determining clinical progress and to assess patient outcomes in clinical trials. However, there has been no investigation into whether clinicians can (i) identify Clade I mpox compared to other viral lesions (ii) differentiate between Clade I mpox lesion stages.

Methodology/Principle findings
The objective of this study was to evaluate inter-rater reliability and agreement between clinicians assessing lesions in patients with Clade I mpox. We presented experienced clinicians with 17 images of Clade I mpox or varicella and asked them to independently indicate the most likely diagnosis–mpox or varicella–and to categorise the lesions according to their stage. When selecting the most likely diagnosis, accuracy varied across all images, the inter-rater reliability was poor (κ = 0.223; z = 10.1) and agreement was moderate (Po = 68%). When categorising lesions according to their type, if a single lesion type was present in the image, inter-rater reliability was moderate (κ = 0.671, z = 40.6) and agreement was good (Po = 78%), but when multiple lesion types were shown in an image, both inter-rater reliability (κ = 0.153, z = 10.5) and agreement (Po = 29%) decreased substantially.

Conclusions
This study demonstrates that there are presently limitations in using visual assessment to diagnose Clade I mpox and evaluate lesion stage and treatment outcomes, which have an impact on clinical practice, public health and clinical trials. More robust indicators and tools are required to inform clinical, public-health, and research priorities, but these must be implementable in countries affected by mpox.
Comprehensive profiling of social mixing patterns in resource poor countries: A mixed methods research protocol
Authors: Aguolu Obianuju Genevieve , Kiti Moses Chapa , Nelson Kristin , Liu Carol Y. , Sundaram Maria , Gramacho Sergio , Jenness Samuel , Melegaro Alessia , Sacoor Charfudin , Bardaji Azucena , Macicame Ivalda , Jose Americo , Cavele Nilzio , Amosse Felizarda , Uamba Migdalia , Jamisse Edgar , Tchavana Corssino , Giovanni Maldonado Briones Herberth , Jarquín Claudia , Ajsivinac María , Pischel Lauren , Ahmed Noureen , Mohan Venkata Raghava , Srinivasan Rajan , Samuel Prasanna , John Gifta , Ellington Kye , Augusto Joaquim Orvalho , Zelaya Alana , Kim Sara , Chen Holin , Kazi Momin , Malik Fauzia , Yildirim Inci , Lopman Benjamin , Omer Saad B. 
Published: June 2024

Background
Low-and-middle-income countries (LMICs) bear a disproportionate burden of communicable diseases. Social interaction data inform infectious disease models and disease prevention strategies. The variations in demographics and contact patterns across ages, cultures, and locations significantly impact infectious disease dynamics and pathogen transmission. LMICs lack sufficient social interaction data for infectious disease modeling.

Methods
To address this gap, we will collect qualitative and quantitative data from eight study sites (encompassing both rural and urban settings) across Guatemala, India, Pakistan, and Mozambique. We will conduct focus group discussions and cognitive interviews to assess the feasibility and acceptability of our data collection tools at each site. Thematic and rapid analyses will help to identify key themes and categories through coding, guiding the design of quantitative data collection tools (enrollment survey, contact diaries, exit survey, and wearable proximity sensors) and the implementation of study procedures. We will create three age-specific contact matrices (physical, nonphysical, and both) at each study site using data from standardized contact diaries to characterize the patterns of social mixing. Regression analysis will be conducted to identify key drivers of contacts. We will comprehensively profile the frequency, duration, and intensity of infants’ interactions with household members using high resolution data from the proximity sensors and calculating infants’ proximity score (fraction of time spent by each household member in proximity with the infant, over the total infant contact time) for each household member.

Discussion
Our qualitative data yielded insights into the perceptions and acceptability of contact diaries and wearable proximity sensors for collecting social mixing data in LMICs. The quantitative data will allow a more accurate representation of human interactions that lead to the transmission of pathogens through close contact in LMICs. Our findings will provide more appropriate social mixing data for parameterizing mathematical models of LMIC populations. Our study tools could be adapted for other studies.
Provider perspectives on screening and treatment for opioid use disorder and mental health in HIV care: A qualitative study
Authors: Knettel Brandon A. , Chen Hillary , Wilson Elena , Agor David , McKellar Mehri S. , Reif Susan 
Published: June 2024

Background
HIV, opioid use disorder (OUD), and mental health challenges share multiple syndemic risk factors. Each can be effectively treated with routine outpatient appointments, medication management, and psychosocial support, leading implementers to consider integrated screening and treatment for OUD and mental health in HIV care. Provider perspectives are crucial to understanding barriers and strategies for treatment integration.

Methods
We conducted in-depth qualitative interviews with 21 HIV treatment providers and social services providers (12 individual interviews and 1 group interview with 9 participants) to understand the current landscape, goals, and priorities for integrated OUD, mental health, and HIV care. Providers were purposively recruited from known clinics in Mecklenburg County, North Carolina, U.S.A. Data were analyzed using applied thematic analysis in the NVivo 12 software program and evaluated for inter-coder agreement.

Results
Participants viewed substance use and mental health challenges as prominent barriers to engagement in HIV care. However, few organizations have integrated structured screening for substance use and mental health into their standard of care. Even fewer screen for opioid use. Although medication assisted treatment (MAT) is effective for mitigating OUD, providers struggle to connect patients with MAT due to limited referral options, social barriers such as housing and food insecurity, overburdened staff, stigma, and lack of provider training. Providers believed there would be clear benefit to integrating OUD and mental health treatment in HIV care but lacked resources for implementation.

Conclusions
Integration of screening and treatment for substance use and mental health in HIV care could mitigate many current barriers to treatment for all three conditions. Efforts are needed to train HIV providers to provide MAT, expand resources, and implement best practices.
Correlation between serum uric acid to high-density lipoprotein cholesterol ratio and atrial fibrillation in patients with NAFLD
Authors: Liu Gaizhen , Zhang Qi , Zhou Meng , Li Baojie , Zhao Jianqi , Bai Rui , Song Xiaosu , Qin Weiwei , Zhang Yonglai 
Published: June 2024

Background
Non-alcoholic fatty liver disease (NAFLD) is independently associated with atrial fibrillation (AF) risk. The uric acid (UA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) has been shown to be closely associated with cardiovascular disease (CVD) and NAFLD. The aim of this study is to clarify whether elevated UHR is associated with the occurrence of AF in patients with NAFLD and to determine whether UHR predicted AF.

Methods
Patients diagnosed with NAFLD in the Department of Cardiovascular Medicine of the Second Hospital of Shanxi Medical University from January 1, 2020, to December 31, 2021, were retrospectively enrolled in this study. The study subjects were categorized into AF group and non-AF group based on the presence or absence of combined AF. Logistic regression was performed to evaluate the correlation between UHR and AF. Sensitivity analysis and subgroup interaction analysis were performed to verify the robustness of the study results. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal cutoff value for UHR to predict the development of AF in patients with NAFLD.

Results
A total of 421 patients with NAFLD were included, including 171 in the AF group and 250 in the non-AF group. In the univariate regression analysis, NAFLD patients with higher UHR were more likely to experience AF, and the risk of AF persisted after confounding factors were adjusted for (OR: 1.010, 95%CI: 1.007–1.013, P<0.001). AF risk increased with increasing UHR quartile (P for trend < 0.001). Despite normal serum UA and HDL-C, UHR was still connected with AF in patients with NAFLD. All subgroup variables did not interact significantly with UHR in the subgroup analysis. The ROC curve analysis showed that the areas under the curve for UA, HDL-C, and UHR were 0.702, 0.606, and 0.720, respectively, suggesting that UHR has a higher predictive value for AF occurrence in NAFLD patients compared to HDL-C or UA alone.

Conclusion
Increased UHR level was independently correlated with a high risk of AF in NAFLD patients.
Joint Hypermobility, Autonomic Dysfunction, Gastrointestinal Dysfunction, and Autoimmune Markers: Clinical Associations and Response to Intravenous Immunoglobulin Therapy
Authors: Pasricha Pankaj J. , McKnight Megan , Villatoro Luisa , Barahona Guillermo , Brinker Jeffrey , Hui Ken , Polydefkis Michael , Burns Robert , McMahan Zsuzsanna H. , Gould Neda , Goodman Brent , Hentz Joseph , Treisman Glenn 
Published: June 2024

INTRODUCTION:
We examined autoimmunity markers (AIM) and autonomic dysfunction in patients with chronic neurogastroenterological symptoms and their relationship to joint hypermobility/hypermobility spectrum disorder (JH/HSD).

METHODS:
AIM positivity was defined as a diagnosis of known autoimmune/autoinflammatory disorder with at least 1 positive seromarker of autoimmunity or at least 2 positive seromarkers by themselves. Three cohorts were studied: (i) retrospective (n = 300), (ii) prospective validation cohort (n = 133), and (iii) treatment cohort (n = 40), administered open-label intravenous immunoglobulin (IVIG).

RESULTS:
AIM positivity was found in 40% and 29% of the retrospective and prospective cohorts, the majority of whom (71% and 69%, respectively) had autoinflammatory disorder. Significantly more patients with AIM had elevations of C-reactive protein (31% vs 15%, P < 0.001) along with an increased proportion of cardiovascular autonomic dysfunction (48% vs 29%; P < 0.001), small fiber neuropathy (20% vs 9%; P = 0.002), and HLADQ8 positivity (24% vs 13%, P = 0.01). Patients with JH/HSD were more likely to have AIM (43% vs 15%, P = 0.001) along with more severe autonomic and gastrointestinal (GI) symptom scores. IVIG treatment was associated with robust improvement in pain, GI, and autonomic symptoms, but adverse events were experienced by 62% of patients.

DISCUSSION:
Autoimmune markers and autonomic dysfunction are common in patients with unexplained GI symptoms, especially in those with JH/HSD. Many patients seem to respond to IVIG treatment, but this needs to be confirmed by controlled trials. These results highlight the need for vigilance for autoimmune and autonomic factors and JH/HSD in patients with neurogastroenterological disorders. Clinicaltrials.gov, NCT04859829.