bluuebunny/crossref_metadata_2025_split huggingface dataset:
FC20-06 - Cultural variation in depressive symptom burden and attribution of mental health ailments among older latinos
Authors: Ng B. 
Published: May 2011

BackgroundThe influence of acculturation and nativity on depression in Latinos remains highly contested. One potential source of ambiguity is variation in their beliefs about the causes of their mental health ailments.MethodsWe conducted cross-sectional analyses of 450 older Latinos attending a rural mental health clinic near the U.S.-Mexico border. Primary diagnosis was grouped in one of 5 categories. The Center for Epidemiological Studies of Depression (CES-D) scale was used to measure depressive symptoms. Cultural variables included nativity and a validated acculturation scale. Patients rated their level of endorsement of 13 causes of mental health ailments A one-way ANOVA was conducted to identify cultural predictors of attribution items.ResultsLatinos had a mean age of 70.9 (SD = 9.1). The most common primary diagnoses were depressive disorders (67.1%) and dementia (15.3%). The mean CES-D score was 15.08 (SD = 18.16), but higher for the more acculturated (p = 0.048), and patients with psychotic (M = 26.31, SD = 19.78) and bipolar (M = 26.05, SD = 19.54) disorders. Acculturation increased attribution of mental health ailments to significant others (ρ = 0.091; p = 0.054), difficulty with work (ρ = 0.162; p = 0.001), and hereditary factors (r = 0.202, 95% CI = 0.002, 0.403). Patients with psychotic disorders were most likely to attribute their symptoms to curses (p = 0.001) and supernatural factors (p = 0.024) compared to other diagnostic categories.ConclusionsAcculturated Latinos attriattribute their mental health ailments to life circumstances. This may intensify depressive symptoms and partly explains the relationship between acculturation and depressive symptoms. Further, the patients’ major diagnosis must be considered when evaluating acculturative influences on depression in psychiatric populations.
FC21-01 - Physical health of residents in psychiatric and social care facilities
Authors: Hjorth P. 
Published: May 2011

BackgroundPrevalence of physical illness among patients suffering from psychiatric illness is higher than in the average population. This is especially true for persons diagnosed with schizophrenia who mainly suffer from heart disease and metabolic disorders. Some of the second generation antipsychotics are likely to cause weight gain and metabolic syndrome associated with a two- to threefold increase in cardiovascular mortality and a twofold increase in all-cause mortality. The quality of the general health care in patients with severe mental illness and the lack of consensus about the prevention of somatic illness in this group of vulnerable patients need to be improved.HypothesisThere is a correlation between the awareness of physical health and the physical health among patients as well as staff members.Material and methodsThe investigation is designed as a randomised controlled intervention study with follow-up after nine months.The study population is from six facilities in the region of North Jutland in Denmark for severe chronically mental ill patients. All six facilities offer specialised social psychiatric treatment. The six facilities have 184 patients and approximately 200 staff members. A subsample of seven patients and seven staff members will be selected from the three interventions facilities and be invited to participate in separate focus groupsIn the intervention facilities, a detailed feedback of all index measures will be distributed to the patients and the staff. Individual health promotion and guidance will be carried out.
FC21-02 - Mental health and social care collaboration: A Cross-national whole network analysis of organisational partnerships in Europe
Authors: Nicaise P. 
Published: May 2011

IntroductionSocially marginalised people with mental health disorders have complex needs that require integrated care. However, mental health and social care sectors are fragmented, and inter-organisational collaboration is challenging.AimA cross-national whole Network Analysis was carried out to detect and interpret patterns of relations between mental health and social care services in several European cities and assess their levels of care integration, following Leutz's levels: linkage, coordination and full integration.MethodData on referrals and service routine meetings were collected in deprived areas of 14 European cities and processed within a Social Network Analysis approach. Structural indicators included degrees, components and overlapping cliques, betweenness centrality and centralisation and brokerage roles. Patterns of collaboration were compared across cities.ResultsFew cities had full integrated services. Whole networks had relatively low densities, including denser sub-networks of similar services. The linkage across sectors remained weaker than the linkage within sectors. Services situated in broker positions were not always integrated nor commissioned for care coordination. The centrality of these services was higher when the linkage density was lower.ConclusionsAlthough differences between structural patterns of mental health and social care networks mainly depend on national care integration policies, the study revealed structural gaps in the achievement of these patterns, whatever the policy model. This could explain why different systems are basically facing the same problems in service delivery despite these differences. These gaps constitute potential weaknesses in the quality of mental health and social care integration at the system level.
FC21-03 - Health-related quality of life of women with and without a mentally ill family member
Authors: Trajanovic L. , Skakic O. , Ilic N. 
Published: May 2011

IntroductionWomen bear most of the burden in taking care of a chronically ill family member, thus exposing their own health and quality of life to risk. It is consider that mental health is the most vulnerable and most frequently affected health domain.ObjectiveThe purpose of this study was to examine the health-related quality of life (HR-QOL) in women who have and have not a mentally ill adult for a family member.MethodMOS Short Form-36 Health Survey (SF-36) questionnaire was used in this study. A total of 118 women were questioned, 54 out of which were taking care of a schizophrenic adult family member, whereas 64 had families with no mentally ill members. The two groups were matched according to age and education level.ResultsWomen with a mentally ill family member had lower scores in all quality of life domains, with the lowest scores in vitality (VT = 48,1), mental health (MH = 51,9), role emotional (RE = 53,1) and general health (GH = 53,5). Exactly the same health dimensions were estimated as the worst by women with no mentally ill family member (VT = 50,1; MH = 57,5; RE = 57,9; GH = 61). Statistically significant difference was observed only in the general health (p < 0.05).ConclusionWomen who are taking care of a chronically mentally ill family member are not so worried about the deterioration of their own mental health, as much as they are about their general state of health. Therefore it is necessary to put an accent on this subject as well, in creating future caregivers health programs.
FC21-04 - Unmet needs differences between male and female inmate population receiving psychiatric care
Authors: Talina M. , Cardoso A.M. , Fortes F. , Morais J. , Correa B. , Xavier M. 
Published: May 2011

IntroductionInmates present higher prevalence of mental and physical disorders and are subject of some kind of social exclusion than the general population. The assessment of unmet needs is crucial for care planning.ObjectivesTo assess and compare the need for care between male and female inmates undergoing psychiatric treatment.AimsDelivery of health and social care in prisons.MethodsA cross-sectional, descriptive study of a non-probabilistic convenience sample of inmates referenced to a forensic psychiatric clinic in Lisbon region, during a year, was performed. The research protocol, besides a specific questionnaire, includes MINI; BPRS; GAF and Camberwell Assessment of Need, Forensic Version (CANFOR).ResultsSeventy nine males (median age 36) and 35 females (median age 32) were receiving psychiatric treatment at the time of the study. Anti-social personality disorder in men (62%) and major depression in women (62.9%) were the most frequent disorders found. Males more often present moderate to high suicide risk (36.7%) than females (28.6%). The number of unmet needs was significantly increased in males (average 6 ± 2.2) than females (4.3 ± 2.2; p< o.oo1). For males, the more frequent unmet needs concerns sexual expression (79.7%), social benefits (77.2%) and psychological distress (63.3%) and for females it was psychological distress, social benefits (62.9% each) and company (51.4%).ConclusionThe results indicate that male inmates have higher behavioral risk and more unmet needs than female inmates. The assessment of needs in prisons is important for the development of strategies concerning care, social integration and prevention of criminal recidivism.
FC21-05 - Clinical and economical effects one year after establishing a decentralized psychiatric outpatient service
Authors: Valdes-Stauber J. , Kilian R. , Putzhammer A. 
Published: May 2011

BackgroundIntensification of outpatient psychiatric care may improve the care quality in community but also increase the total care costs in the first period as well as reduce in-patient cumulative length of stay over the medium term.ObjectiveWe investigate the economic and clinical effects of establishing of a psychiatric outpatient-service in a South-Bavarian catchment area one year before and one year after establishing.MethodsAll admitted patients in a psychiatric acute ward corresponding to the catchment area of the new outpatient- service are registered one year before establishing (2007, n = 145) and one year after (2009, n = 167). Associations between clinical, demographic and economical variables were investigated by means of multivariate regression analysis. Control variables are sex, age and psychiatric diagnostic groups.ResultsCumulative length of stay (b = −1.72, p = 0.68) and number of admissions (b = −0.10; p = 0.28) decreased, but not significantly. In-patient as well as global care costs remains the same. Costs of prescribed psychopharmacological drugs (b = 54.4; p = 0.36) and outpatient psychiatric care (b = 67.8; p = 0.15) increase obviously, but not significantly.ConclusionsAdditional implementation of an outpatient-service is not related to increase of service use costs. We found out, that in the first year there is a demand increasing effect. The effects on in-patient parameters and diagnosis groups have to be observed for the following years.
FC21-07 - Trends in health-related quality of life and health service use associated with comorbid diabetes and major depression in South Australia, 1998–2008
Authors: Atlantis E. , Goldney R. , Eckert K. , Taylor A. , Phillips P. 
Published: May 2011

PurposeTo investigate trends in health-related quality of life and health service use associated with diabetes and/or major depression in South Australia from 1998 to 2008.MethodsData analyzed were from 9,059 persons aged ≥15 years who participated in representative surveys of the South Australian population in 1998, 2004 and 2008. Major depression was determined using the mood module of the Primary Care Evaluation of Mental Disorders (PRIME-MD). Diagnosed diabetes and health service use was determined by self-report. Health-related quality of life was assessed using the 36-item Short-Form Health Survey (SF-36) and the 15-item Assessment of Quality of Life (AQoL) instruments. Weighted age-standardized and multiple-adjusted means of dependent measures were computed.ResultsThe prevalence of diabetes only, major depression only, and comorbid diabetes and major depression increased by 74%, 36% and 53% from 1998 to 2008. Mean health-related quality of life scores were 9% to 41% lower (worse), and health service use was 49% higher for persons with comorbid diabetes and major depression than for those with diabetes only (all P-values < 0.05), consistently over the 10-year period.ConclusionsIf past trends continue, our results suggest that the population health and economic burden of comorbid diabetes and major depression will grow similarly over the next decade or so. These trends have important implications for making health policy and resource allocation decisions.
FC22-02 - Effect of quetiapine on functioning and quality of life in bipolar depression
Authors: Gustafsson U. , Fajutrao L. 
Published: May 2011

IntroductionDepression symptoms in bipolar disorder have debilitating effects on functioning and quality of life (QoL).ObjectivesTo assess effects of 8 weeks of quetiapine monotherapy on functioning and QoL in patients with bipolar depression (BPD).AimsTo evaluate functioning and QoL using patient-reported outcomes.MethodsData from 4 trials (BOLDER I and II; EMBOLDEN I and II) of quetiapine (300 and 600 mg/day) in BPD were combined (n = 2593). The Sheehan Disability Scale (SDS) measured functioning (BOLDER II; EMBOLDEN I and II) and the QoL Enjoyment and Satisfaction Questionnaire (Q-LES-Q)-Short Form measured QoL (BOLDER I and II; EMBOLDEN II).ResultsQuetiapine improved overall functioning (mean change [SE] in SDS total score: -7.23 [0.49], -7.49 [0.49], with quetiapine 300 mg/day and quetiapine 600 mg/day, respectively vs placebo (-5.91 [0.54]); P < 0.01 for both). Both doses improved functioning in SDS domains of work/school, social life, and family life/home responsibilities vs placebo (P < 0.05). Quetiapine 600 mg/day reduced days missed from work/school and productivity losses vs placebo (P < 0.01). QoL was improved with both quetiapine doses vs placebo (P < 0.001; least squares mean changes (SE) in Q-LES-Q total score from baseline to Day 57: 9.69 (0.51), 9.95 (0.50), and 6.81 (0.54) with quetiapine 300 mg/day, quetiapine 600 mg/day, and placebo, respectively). Tolerability was consistent with the known safety profile of quetiapine.ConclusionsQuetiapine treatment (300 and 600 mg/day) for 8 weeks significantly improved functioning and QoL vs placebo in patients with BPD.Supported by funding from AstraZeneca Pharmaceuticals LP.
FC22-03 - Annual periodicity and personality: Season of birth is associated with affective temperaments
Authors: Gonda X. , Rihmer Z. , Fountoulakis K.N. , Pompili M. , Erdös P. , Ormos M. 
Published: May 2011

ObjectivesPeriodicity, cyclicity, and annual rhythms are inherent characteristics of living organisms, and have also been reported for diverse physiological and pathological conditions and phenomena. Season of birth was also associated with central monoamine and monoamine metabolite levels in several studies. Furthermore, several studies indicate a significant effect of season of birth on personality traits and characteristics. A relationship between birth season and novelty seeking has been described and confirmed in several studies. However, affective temperaments have not so far been studied with respect to their association with birth season.AimsThe aim of our present study was to investigate the possible association between affective temperaments and season of birth in a nonclinical sample.Methods366 university students completed the standardized Hungarian version of the TEMPS-A. Ordinary Least Squares regression was applied to explain the relationship between TEMPS-A subscales and birth season of the respondents.ResultsWe found a significant association between temperament scores and birth season in case of the Hyperthymic, Cyclothymic, Irritable and Depressive temperaments, while no significant results emerged for the Anxious temperament.ConclusionsOur results provide further evidence for an association between season of birth and personality, extending the results to affective temperaments as well. Furthermore, our results can be related to clinical observations concerning the seasonal variation of onset and hospitalization due to affective episodes, thus our results also have clinical significance.
Fc22-04 Effect of folic acid add-on treatment in patients with acute mania on clinical symptoms and urinary 6-sulfatoxymelatonin: double blind placebo-controlled trial
Authors: Modabbernia A. , Ashrafi M. , Rahiminejad F. , Akhondzadeh S. 
Published: May 2011

IntroductionCyclic changes in symptomatology, sleep disorders and changes in body temperature in bipolar disorder suggest a circadian rhythm disorder and its most important regulator, melatonin. Folate is both a melatonin enhancer and has been shown to be lower in manic patients.ObjectivesTo investigate the association between melatonin level (by its most important metabolite, urinary 6-sulfatoxymelatonin) and clinical score of bipolar patients after folate supplementation of their medication.MethodsForty eight patients (who had at least one manic episode based on DSM-IV) were included in the study and out of these patients 8 patients dropped out during the study due to changes in diagnosis and 40 were randomized to group A (21 patients, folic acid+lithium+resperidone) and group B (19 patient, placebo +lithium+resperidone). Also 8 controls were selected for comparison of urinary 6 sulfatoxymelatonin levels. Morning Urinary 6 sulfatoxy melatonin and Young Mania Rating Scale were measured in the beginning and at the end of the first month.ResultsThere were significant differences between group A and B in the alteration of level of urinary 6-sulfatoxymelatonin measured during the study period(11.7 ± 13.4 Vs -6 ± 16.2 p< 0.001)both groups had significantly lower 6MT than controls and this persisted till the end of the first month in both groups. Significant difference was seen between alteration of YMRS in two groups(34.5 ± 3.9 Vs 30.1 ± 3.8 p < 0.001).ConclusionOur findings showed that folic acid may be effective as an adjunct to main mania treatment, and it may exert its effect partially due to changes in melatonin profile.
FC23-01 - Affective temperament and and attachment - also a study about depression and anxiety in a young adult population
Authors: Cordeiro R.C. 
Published: May 2011

IntroductionThe transition from adolescence into adulthood is a stage of human development characterized by a broad change of physical and psychological dimensions.Objectives and aimsTo examine the associations between affective temperaments (depressive, cyclothymic, hyperthymic, irritable and anxious) and attachment styles in a population of adolescents and young adults.MethodSample: 760 nursing students from 4 Higher Schools. Data was collected by a self-report questionnaire, with several measures: Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A), (Akiskal & Akiskal, 2005a, Figueira et al., 2008), the Intimate Friendship Scale (Sharabany, 1994; Cordeiro, 2007), Father/Mother Attachment Questionnaire - QVPM, Version IV (Matos & Costa, 2001a), Love Attachment Questionnaire - QVA, Version III (Matos & Costa, 2001b), Beck Depression Inventory (Beck, 1967; Vaz Serra & Pio de Abreu, 1973ab) and the State-Trait Anxiety Inventory - STAI - Forms Y-1 and Y-2 (Spielberger, Gorsuch & Lushene, 1997, Silva & Campos, 1998, Santos & Silva, 1997).ResultsThe participants are mostly female (83.3%) with an average age of 21.3 years.The dominant affective temperament for the total of the studied population was the depressive temperament but the results suggested a balance between anxious and irritable temperaments and also between depressive and cyclothymic temperaments.ConclusionThe attachment to a best friend has shown to be associated with anxious temperament. All temperaments were associated with several factors of attachment to the mother, the father or to love peers.A correlation between temperament and anxiety and between temperament and depressive symptoms were also found.
FC23-02 - Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly
Authors: Ancelin M.-L. , Carrière I. , Boulenger J.-P. , Malafosse A. , Stewart R. , Cristol J.-P. , Ritchie K. , Chaudieu I. , Dupuy A.-M. ,   The Esprit Study
Published: May 2011

BackgroundLipids appear to mediate depressive vulnerability in the elderly, however, sex differences and genetic vulnerability have not been taken into account in previous prospective studies.MethodsDepression was assessed in a population of 1040 women and 752 men aged 65 years and over at baseline and after 7-year follow-up. Clinical level of depression (DEP) was defined as having either a score of 16 and above on the Centre for Epidemiology Studies Depression scale or a diagnosis of current major depression on the Mini International Neuropsychiatric Interview. Lipid levels, apolipoprotein E and serotonin transporter linked promoter region (5-HTTLPR) genotypes were evaluated at baseline.ResultsMultivariate analyses adjusted by socio-demographic and behavioral variables, measures of physical health including ischemic pathologies, and genetic vulnerability indicated gender-specific associations between dyslipidemia and DEP, independent of the use of lipid lowering agents or apolipoprotein E status. Men with low LDL-cholesterol levels had twice the risk of prevalent and incident DEP whereas in women low HDL-cholesterol levels were found to be significantly associated with increased prevalent DEP (OR = 1.5) only. A significant interaction was observed between low LDL-cholesterol and 5-HTTLPR genotype, men with s/s or s/l genotype being at increased risk of DEP (OR = 6.0 and 2.7, respectively). No significant gene-environment interaction was observed for women.ConclusionsDEP is associated with higher atherogenic risk in women (low HDL-cholesterol), whereas the reverse is observed in men (low LDL-cholesterol). Late-life depression may have a complex gender-specific etiology involving genetic vulnerability in men.
FC23-03 - Estrogen receptor polymorphisms and late-life depression
Authors: Ryan J. , Scali J. , Carriere I. , Peres K. , Rouaud O. , Scarabin P.-Y. , Ritchie K. , Ancelin M.-L. 
Published: May 2011

IntroductionDespite a putative role for estrogen in depression, studies on the association between depression and estrogen receptor (ER) polymorphisms are surprisingly lacking.ObjectivesTo determine the association between ER polymorphisms and late-life depression in 6809 men and women and to investigate factors which could modify this association.MethodCommunity-dwelling elderly aged 65 years and older were recruited in France as part of the Three City Study. Depression was assessed using the Centre for Epidemiological Studies Depression Scale and the Mini-International Neuropsychiatric Interview, according to DSM-IV criteria. The association between five polymorphisms of the ER-α and ER-β with depression was determined using multi-adjusted logistic regression models.ResultsMen with the AA genotype of the ER-β rs4986938 polymorphism had an increased risk of depression, while in women, carriers of the A allele for the ER-β rs1256049 had an increased risk. Subsequent analysis indicated that the increased risk in women occurred only in those not using hormone treatment. In women the CC and GG genotypes of the ER-α PvuII and XbaI, respectively were associated with a decreased risk of depression. A significant interaction between the ER-α PvuII and ER-β rs4986938 polymorphisms suggests they may act together to modify the depression risk.ConclusionsSex-specific associations between ER polymorphisms and depression have been identified, with HT appearing to be beneficial for genetically vulnerable women. These findings of distinct genetic susceptibility to late-life depression may be important for designing novel hormone-based therapies that would have optimal effectiveness in sub-groups of depressed women and men.