bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators to engaging with a digital self‐management programme for painful distal upper limb musculoskeletal disorders: A qualitative exploratory study
Authors: Mason Samantha J. , Brading Lucy M. , Kane Kathleen , Conaghan Philip G. , Kingsbury Sarah R. , McHugh Gretl A. 
Published: June 2024

AbstractIntroductionPeople living with a painful distal upper limb musculoskeletal disorder (DUL‐MSD) often experience pain, difficulty in doing everyday tasks and a reduced quality of life. Currently, there are challenges in the treatment of DUL‐MSDs, highlighting the need to develop innovative approaches to rehabilitation. A potential solution is to develop and implement a digital self‐management rehabilitation programme focussing on optimising recovery, improving function and reducing pain. Before developing this programme, we aimed to identify the barriers and facilitators to using a digital health intervention (DHI) for self‐management of DUL‐MSDs.ObjectiveThis study aimed to investigate the potential barriers and facilitators to using a DHI with people living with DUL‐MSDs and healthcare professionals (HCPs).MethodsA qualitative exploratory study was carried out with purposely selected participants consisting of 15 participants with DUL‐MSDs and 13 HCPs. Three focus groups (FGs) and four semistructured interviews with DUL‐MSD participants and semistructured interviews with 13 HCPs were conducted. FGs and interviews were digitally recorded, transcribed and analysed using reflexive thematic analysis.ResultsTo address challenges in the care and management of DUL‐MSDs, both HCPs and people living with a DUL‐MSD welcomed the development of a DHI. This study identified several barriers and facilitators that would influence engagement with a digital intervention. Findings suggest that in developing a DHI, attention needs to be paid to digital design features, usability, tailoring, personalisation and consideration of how well usual care could be replicated digitally without direct HCP involvement.ConclusionThe identified digital design features of importance to participants will inform the design of a digital self‐management rehabilitation programme for people living with DUL‐MSDs. Addressing the barriers and facilitators to engagement with a DHI is essential in ensuring its relevance and acceptability to those who will use it.Patient or Public ContributionPatient and Public Involvement and Engagement (PPIE) was integral throughout the study. PPIE members contributed to the development and planning of this study, checked and confirmed the relevance of the findings and are involved in the dissemination plans.
Digital Reflective Practice in Textile Design Studio Courses: Perspectives from Pakistan
Authors: Hameed Umer , Mimirinis Mike 
Published: June 2024

AbstractThis multiple case study aimed to investigate how digital reflective practice (DRP) influences the creative process of textile design students. Interviews were conducted with textile design instructors, heads of department, and students from four higher education textile design departments in Pakistan. The main themes elicited from the four case studies were teachers’ and students’ perceptions of DRP, challenges to its implementation, and prospects for DRP in the context of textile studio design. Digital technologies can improve students' creativity and comprehension of tasks in textile design studio courses through reflection. Furthermore, teachers can play a crucial role in helping students to utilise digital reflection technologies through mentorship.
Evaluating the effectiveness of the Complex Behaviour Forum—A multisystem approach to supporting people with complex challenging behaviour
Authors: Carberry Trent , Hutchison Sarah , Wardale Simon , Demir Rebeka , Vassos Maria 
Published: June 2024

AbstractBackgroundThis study assessed the effectiveness of a cross‐departmental case review panel—the Multicap Complex Behaviour Forum (CBF)—in reducing challenging behaviour exhibited by people with intellectual disabilities.MethodsThirty participants (15 CBF participants and 15 matched‐control participants) took part in the study. Behavioural data was collected for each CBF participant (and their matched control) for the three‐month period before entering the CBF, during their time in the CBF, and the 3 months after exiting the CBF.ResultsThere was a significant interaction of group and time observed, with the CBF participants showing more change in behavioural incidents across time. Associated with this change was a noticeable reduction in staff injury costs related to the challenging behaviour of the CBF participants.ConclusionsThis study demonstrates that positive behavioural and organisational outcomes are enhanced by fostering collaboration across multiple organisational systems when it comes to supporting people who exhibit challenging behaviours.
Research Review: Social cognition and everyday social skills in children and adolescents with attention‐deficit/hyperactivity disorder: a meta‐analysis of case–control studies
Authors: Haza Belen , Gosling Corentin J. , Ciminaghi Flavia , Conty Laurence , Pinabiaux Charlotte 
Published: June 2024

BackgroundPrevious studies that have assessed social cognition in Attention‐Deficit/Hyperactivity Disorder (ADHD) have produced inconsistent findings. To summarize these data and shed light upon moderators that may explain observed inconsistencies, we conducted a systematic review and meta‐analysis exploring social cognition (Theory of Mind (ToM), Empathy, Facial and Non‐Facial Emotion Recognition) and Everyday Social Skills in children and adolescents with ADHD.MethodsThe current meta‐analysis involved 142 studies including 652 effect sizes. These studies compared children and adolescents with ADHD (n = 8,300) and with typical development (n = 7,983).ResultsParticipants with ADHD exhibited moderate to very large deficits in ToM (SMD = 0.84, 95% CI = 0.68–0.99), Facial Emotion Recognition (SMD = 0.63, 95% CI = 0.46–0.81), and Everyday Social Skills (SMD = 1.23, 95% CI = 1.08–1.37). The magnitude of these impairments was similar when considering effect sizes adjusted for some covariates and the methodological quality of the studies. Few studies have investigated Empathy and Non‐Facial Emotion Recognition, which precludes definitive conclusions.ConclusionsChildren and adolescents with ADHD experience robust impairments in ToM, Facial Emotion Recognition and Everyday Social Skills. Future studies should explore whether these deficits are a consequence of difficulties in other areas of cognition (e.g., executive functioning). We have made all our raw data open access to facilitate the use of the present work by the community (e.g., clinicians looking for tools, assessing social impairments, or researchers designing new studies).
Age affects drug survival rates of interleukin (IL)‐17 and IL‐23 inhibitors in patients with plaque psoriasis: Results from a retrospective, multicentric, multi‐country, cohort study
Authors: Chiricozzi Andrea , Coscarella Giulia , Puig Luis , Vender Ron , Yeung Jensen , Carrascosa José‐Manuel , Piaserico Stefano , Gisondi Paolo , Lynde Charles , Ferreira Paulo , Bastos Pedro Mendes , Dauden Esteban , Leite Luiz , Valerio Joana , del Alcázar‐Viladomiu Elena , Vilarrasa Eva , Llamas‐Velasco Mar , Alessandri‐Bonetti Mario , Messina Francesco , Bruni Manfredo , Di Brizzi Eugenia Veronica , Ricceri Federica , Nidegger Alessia , Hugo Jan , Mufti Asfandyar , Daponte Athina‐Ioanna , Teixeira Laetitia , Balato Anna , Romanelli Marco , Prignano Francesca , Gkalpakiotis Spyridon , Conrad Curdin , Lazaridou Elizabeth , Rompoti Natalia , Stratigos Alexander J. , Nogueira Miguel , Peris Ketty , Torres Tiago 
Published: June 2024

AbstractBackgroundScarce data related to the drug survival of biologic agents in psoriasis patients aged ≥65 years is available.ObjectivesTo evaluate the drug survival of interleukin (IL)‐23 or the IL‐17 inhibitors approved for the treatment of moderate‐to‐severe psoriasis in elderly patients (aged ≥65 years), compared with younger adult patients (aged <65 years), and to identify clinical predictors that can influence the drug survival.MethodsThis retrospective multicentric cohort study included adult patients with moderate‐to‐severe psoriasis, dissecting two‐patient subcohorts based on age: elderly versus younger adults. Kaplan–Meier estimator and proportional hazard Cox regression models were used for drug survival analysis.ResultsWe included 4178 patients and 4866 treatment courses; 934 were elderly (1072 treatment courses), and 3244 were younger patients (3794 treatment courses). Drug survival, considering all causes of interruption, was higher in patients aged <65 years than in elderly patients overall (log‐rank p < 0.006). This difference was significant for treatment courses involving IL‐23 inhibitors (p < 0.001) but not for those with IL‐17 inhibitors (p = 0.2). According to both uni‐ and multi‐variable models, elder age was associated with an increased risk of treatment discontinuation (univariable analysis: HR: 1.229, 95% CI 1.062–1.422; p < 0.006; multivariable analysis: HR: 1.199, 95% CI 1.010–1.422; p = 0.0377). Anti‐IL‐23 agents were associated with a reduced likelihood of treatment discontinuation after adjusting for other variables (HR: 0.520, 95% CI 0.368–0.735; p < 0.001). Being previously treated with IL‐17 inhibitors increased the probability of discontinuation.ConclusionsElderly patients with psoriasis have an increased risk of biologic treatment discontinuation compared with younger adult patients, particularly, if being treated with IL‐23 inhibitors. However, in stratified analyses conducted in elderly patients, IL‐23 inhibitors showed higher drug survival rates than IL‐17 inhibitors.
Application of resveratrol butyric acid derivatives in the processing, physicochemical characterization, and the shelf‐life extension of Chinese sausages low in sodium nitrite
Authors: Huang Ping‐Hsiu , Chen Yu‐Wei , Fan Hua‐Jin , Chen Shin‐Yu , Tain You‐Lin , Hsieh Chang‐Wei , Hou Chih‐Yao , Shih Ming‐Kuei 
Published: June 2024

AbstractResveratrol butyrate esters (RBEs) are novel resveratrol (RSV) derivatives synthesized by esterification with butyric acid. In addition, ED2 (3,4′‐di‐O‐butanoylresveratrol) and ED4 (3‐O‐butanoylresveratrol) in different structural monomers of RBEs have been shown as abundant cellular antioxidants. Therefore, this study was performed to apply RSV and its esterified derivatives in the manufacturing and preservation of Chinese sausage, investigated these ingredients' impact on the sausage's physicochemical properties and changes during storage, and evaluated the feasibility of minimizing sodium nitrite's use in sausage production. This study showed that a high dose (500 ppm) of ED2 and ED4 (with the added 25 mg/kg of sodium nitrite) were effective in maintaining the color of sausages and extending the shelf‐life for at least 30 days in refrigerated storage, which was consistent with 150 mg/kg sodium nitrite. Altogether, ED2 or ED4 can potentially reduce sodium nitrite usage by 83% while preventing lipid oxidation and antimicrobial effects, thereby effectively maintaining sausage product stability. Hence, RBEs facilitate the development of natural functional food additives that provide antioxidant benefits products for all ages of people, namely widely used in any processed food that requires antioxidant functionality or as dietary supplements.
Haptic Sensations Modulate Judgment of Words that Elicit Self‐referent Memory
Authors: Ikeda Toshiki , Takeda Yuji 
Published: June 2024

AbstractPrevious studies have reported that soft haptic sensations influence higher‐order cognition, but few studies have investigated effects of soft haptic sensations on the recall of episodic memories. The present study examined whether or not holding a soft object influences the recall of episodes. Participants held either a soft or hard cushion and performed tasks in which they recalled episodic memories. On each trial, a pleasant or unpleasant trait word was presented. In Experiment 1, the participants judged whether or not the word elicited an autobiographical memory. In Experiment 2, the participants judged whether or not the word elicited a memory of an episode involving their caregiver. In Experiment 1, the number of self‐referent judgments for unpleasant words was smaller when participants held a soft cushion than when they held a hard cushion. In Experiment 2, holding soft or hard cushions had no significant effect on the number of caregiver‐referent judgments. These results suggest that effects of soft haptic sensations on the recall of positive and negative autobiographical memories are asymmetrical.
High‐resolution cathodoluminescence of calcites from the Cold Bokkeveld chondrite: New insights on carbonatation processes in CM parent bodies
Authors: Guigoz Vincent , Seret Anthony , Portail Marc , Ferrière Ludovic , Libourel Guy , Connolly Harold C. , Lauretta Dante S. 
Published: June 2024

AbstractCarbonates, as secondary minerals found in CM chondrites, have been widely employed for reconstructing the composition of the fluids from which they precipitated. They also offer valuable insights into the hydrothermal evolution of their parent bodies. In this study, we demonstrate that high‐resolution cathodoluminescence (HR‐CL) analyses of calcites derived from the brecciated Cold Bokkeveld CM2 chondrite can effectively reveal subtle compositional features and intricate zoning patterns. We have identified two distinct types of cathodoluminescence (CL) centers: a blue emission band (approximately 375–425 nm), associated with intrinsic structural defects, and a lower energy orange extrinsic emission (around 620 ± 10 nm), indicating the presence of Mn cations. These compositional variations enable discrimination between the calcite grain types previously designated as T1 and T2 in studies of CM chondrites. T1 calcites exhibit variable CL and peripheral Mn enrichments, consistently surrounded by a rim composed of Fe‐S‐rich serpentine–tochilinite assemblage. Conversely, T2 calcites display homogeneous CL and more abundant lattice defects. These polycrystalline aggregates of calcite grains, devoid of serpentine, contain Fe‐Ni sulfide inclusions and directly interface with the matrix. We propose that changes in the Mn content of calcite (indicated by the intensity of orange CL emission) are influenced by variations in redox potential (Eh) and pH of the fluid phase. This proposed hydrothermal evolution establishes a parallel between terrestrial serpentinization followed by carbonation processes and the aqueous alteration of CM chondrites, warranting further exploration and investigation of this intriguing similarity.
An 8‐week secular mindfulness‐based training program for schoolteachers increases dispositional mindfulness, self‐reported workplace well‐being, visuoconstructive abilities, and processing speed
Authors: Heredia Luis , Ventura David , Torrente Margarita , Vicens Paloma 
Published: June 2024

AbstractPrevious research has reported that schoolteachers are an at‐risk population for stress and anxiety‐related psychological disorders. High stress levels have been linked to the suboptimal use of executive functions, abilities which are a major component of effective job performance in educational contexts. In the present study, 99 teachers from five primary schools in Spain were randomly assigned to a mindfulness training group or wait‐list control group. All groups were assessed for dispositional mindfulness, anxiety levels, self‐reported well‐being, and neuropsychological performance (including attention, mental flexibility and inhibitory control, visuoconstructive abilities and visual memory, verbal fluency and processing speed) prior to and following the training program. The results showed significant differences between the groups in terms of dispositional mindfulness, workplace well‐being, visuoconstructive abilities, and one of the processing speed indexes. A within‐group analysis indicated a general trend toward improvement in the training group, mainly in dispositional mindfulness and verbal fluency. The assessment of neuropsychological performance in this study also contributes to expanding the existing body of knowledge on the effects of mindfulness‐based programs using behavioral measures in a research field that heavily relies on self‐reported measures.
Fiscal and macroprudential policy coordination for stabilization purposes
Authors: Malmierca‐Ordoqui María 
Published: June 2024

AbstractThe COVID‐19 pandemic has highlighted the need of maintaining financial and economic stabilization to mitigate the negative effects of the health crisis. In the context of a currency area, national governments count on national fiscal and macroprudential instruments to stabilize their own economy. Through a DSGE model for a monetary union I assess the welfare implications of different macroprudential‐fiscal policy combinations, that are set with stabilization purposes. The findings confirm that for a supply and a demand shock, as the ones responsible for the economic crisis of 2020, the stabilizing policy mix might deteriorate welfare. By contrast, after a financial shock, similar to that of the Great Recession, the stabilizing policy combination strategies always achieve welfare gains.
Among‐population variation in drought responses is consistent across life stages but not between native and non‐native ranges
Authors: Nagy Dávid U. , Thoma Arpad E. , Al‐Gharaibeh Mohammad , Callaway Ragan M. , Flory S. Luke , Frazee Lauren J. , Hartmann Matthias , Hensen Isabell , Jandová Kateřina , Khasa Damase P. , Lekberg Ylva , Pal Robert W. , Samartza Ioulietta , Shah Manzoor A. , Sheng Min , Slate Mandy , Stein Claudia , Tsunoda Tomonori , Rosche Christoph 
Published: June 2024

Summary

Understanding how widespread species adapt to variation in abiotic conditions across their ranges is fundamental to ecology. Insight may come from studying how among‐population variation (APV) in the common garden corresponds with the environmental conditions of source populations. However, there are no such studies comparing native vs non‐native populations across multiple life stages.

We examined APV in the performance and functional traits of 59 Conyza canadensis populations, in response to drought, across large aridity gradients in the native (North America) and non‐native (Eurasia) ranges in three experiments. Our treatment (dry vs wet) was applied at the recruitment, juvenile, and adult life stages.

We found contrasting patterns of APV in drought responses between the two ranges. In the native range, plant performance was less reduced by drought in populations from xeric than mesic habitats, but such relationship was not apparent for non‐native populations. These range‐specific patterns were consistent across the life stages.

The weak adaptive responses of non‐native populations indicate that they can become highly abundant even without complete local adaptation to abiotic environments and suggest that long‐established invaders may still be evolving to the abiotic environment. These findings may explain lag times in invasions and raise concern about future expansions.
Association between sex of the individual with untreated cleft lip and social judgement made by lay persons: A cross‐sectional study
Authors: Maia Ana Carolina Del‐Sarto Azevedo , Lima Stefanni Olga Aguiar Sales , Jural Lucas Alves , Moreira David Costa , Maia Lucianne Cople , Tanaka Orlando Motohiro , Pithon Matheus Melo , Prado Fabio Ornellas 
Published: June 2024

AbstractObjectiveTo assess whether there is an association between an individual's sex and social judgements made by lay persons regarding untreated cleft lip.Materials and MethodsLay individuals over 18 years old were recruited through an application to respond online to two questionnaires: a sociodemographic survey and the Brazilian Version of Lay Persons' Social Judgements about Cleft‐lip Scale (B‐LSojCleft‐S). B‐LSojCleft‐S comprises 14 items evaluating social judgements made by laypersons concerning different types of untreated cleft lips in teenagers. The 14 items are linked to 8 images featuring untreated cleft lips and 1 image without a cleft (control). Higher scores represented more favourable social judgements. Independent samples t‐test, paired, and multiple linear regression were conducted (P < 0.05). The study assessed judgements of untreated cleft lips in male and female adolescents using the B‐LSojCleft‐S.ResultsThe mean age of the 217 participants was 37.78 ± 12.39 years, predominantly women (72.7%), married (47.7%), with a monthly income below three minimum wages (35.6%) in the majority of cases. Significantly higher social judgement scores were observed in the control group (no cleft) compared to any type of cleft (P < 0.001), with similar scores obtained for the same types of clefts with female or male images (P > 0.05). The participant's sex is associated with social judgement scores (F [1, 214] = 6.318, P = 0.013; adjusted R2 = 0.024), with females making more favourable judgements than males (P < 0.05).ConclusionsIndividuals with cleft lips receive more negative social judgement scores, regardless of their own sex. Women make better social judgements than men.
Intentional Dural Resection during en bloc Spinal Resection Could Provide a Secure Surgical Margin for Patients with Recurrent Spinal Tumors
Authors: Du Zhiye , Tang Xiaodong , Cai Zhenyu , Wang Han , Wei Ran , Wang Jun 
Published: June 2024

ObjectiveIt is always difficult to obtain a comfortable surgical margin for patients with recurrent malignant or invasive benign spinal tumors. Tumor intraspinal invasion and dural adhesion are the essential reasons. There are always residual tumor cells maintained at the edge of dura. Dural resection is a key point to obtain a comfortable surgical margin for such cases. Whether such patients benefit from this risky surgical procedure is unknown. This study aims to understand better the oncological results, associated risks, and neurological function of this risky surgical procedure.MethodsWe retrospectively reviewed clinical data from six consecutive patients who registered spinal tumors in our institute and underwent dural resection during en bloc spinal resection from June 2013 to May 2020. The demographic and perioperative data, oncological outcomes, complications, and neurological status were collected and analyzed.ResultsAll six patients were followed up for 24 to 46 months (mean follow‐up time: 32.8 months). Local recurrence was detected in one patient (1/6, 16.7%) at 36 months postoperatively and in five patients with no evidence of disease at the last follow up (survival rate 83.3%). Eleven complications occurred in four patients (66.7%), and the dural resection‐related complications included only four cases of cerebrospinal fluid leakage (CSFL), which accounted for 36.4% (4/11) of all complications. Neurologic status evaluated by the Frankel grade showed improvement of one grade in one case and deterioration of one to two grades in five patients immediately after surgery. All deterioration cases recovered to the preoperative level 6 months after the operation.ConclusionDural resection is significant for patients with dura matter invaded by recurrent primary malignant or invasive benign spinal tumors with the purpose of clinical cure. This study demonstrated that in strictly selected cases, intentional dural resection could provide satisfying local control and long‐term disease‐free survival with acceptable complications and satisfying neurological function.