bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Design, Synthesis and Biological Evaluation of New Arylpiperazine Derivatives Bearing a Flavone Moiety as α1‐Adrenoceptor Antagonists.
Authors: Jin Jing , Wang Xiao‐Bing , Kong Ling‐Yi 
Published: June 2011

AbstractEighteen title derivatives, bearing a flavone and an arylpiperazine moiety, are synthesized to evaluate the influence of alkyl substituents at the terminal piperazine nucleus on the α1‐AR antagonistic activity.
ChemInform Abstract: Organocatalytic versus Iron‐Assisted β‐Boration of Electron‐Deficient Olefins.
Authors: Bonet Amadeu , Sole Cristina , Gulyas Henrik , Fernandez Elena 
Published: June 2011

AbstractThe influence of Fe and/or phosphine catalysis on the β‐borylation of α,β‐unsaturated carbonyl or imine compounds is studied.
ChemInform Abstract: Enantioselective Syntheses of syn‐ and anti‐β‐Hydroxyallylsilanes via Allene Hydroboration‐Aldehyde Allylboration Reactions.
Authors: Chen Ming , Roush William R. 
Published: June 2011

AbstractAt temperatures below ‐40°C, the hydroboration proceeds under kinetic control via an intermediate (Z)‐isomer and the syn‐β‐hydroxyallylsilanes (III) arise as the only products.
ChemInform Abstract: Activation of the Si—B Linkage: Copper‐Catalyzed Addition of Nucleophilic Silicon to Imines.
Authors: Vyas Devendra J. , Froehlich Roland , Oestreich Martin 
Published: June 2011

AbstractA variety of aldehyde‐ and ketone‐derived imines is subjected to the reaction with silicon nucleophile (II) to afford the α‐silylated secondary and tertiary amines.
ChemInform Abstract: Chiral Magnesium BINOL Phosphate‐Catalyzed Phosphination of Imines: Access to Enantioenriched α‐Amino Phosphine Oxides.
Authors: Ingle Gajendrasingh K. , Liang Yuxue , Mormino Michael G. , Li Guilong , Fronczek Frank R. , Antilla Jon C. 
Published: June 2011

AbstractThe use of phosphine oxides bearing aromatic substituents allows the preparation of a broad spectrum of biologically interesting target compounds.
ChemInform Abstract: Tandem Phospha‐Friedel—Crafts Reaction Toward Curved π‐Conjugated Frameworks with a Phosphorus Ring Junction.
Authors: Hatakeyama Takuji , Hashimoto Sigma , Nakamura Masaharu 
Published: June 2011

Abstractm‐Teraryl iodides are subjected to lithium—halogen exchange with subsequent trapping with PCl3 and tandem phospha‐Friedel—Crafts reaction to afford the heptacyclic phosphine sulfudes (II).
ChemInform Abstract: Magnetically Separable and Reusable Copper Ferrite Nanoparticles for Cross‐Coupling of Aryl Halides with Diphenyl Diselenide.
Authors: Swapna Kokkirala , Murthy Sabbavarapu Narayana , Nageswar Yadavalli Venkata Durga 
Published: June 2011

AbstractThe use of magnetically separable and recyclable CuFe2O4 system offers significant improvements concerning operational simplicity in the synthesis of both aryl and alkyl selenides.
ChemInform Abstract: Asymmetric α‐2‐Tosylvinylation of in situ Generated N‐2‐Tosylvinyl Proline‐Derived Ammonium Ylides.
Authors: Igarashi Tomohito , Tayama Eiji , Iwamoto Hajime , Hasegawa Eietsu 
Published: June 2011

AbstractIn most cases, the title reaction proceeds with good diastereo‐ and enantioselectivity to produce synthons for ring expansion in N‐heterocycle chemistry.
ChemInform Abstract: Design, Synthesis and Antibacterial Activity of 3‐Methylenepyrrolidine Formyl Hydroxyamino Derivatives as Novel Peptide Deformylase Inhibitors.
Authors: Shi Wei , Ma Haikun , Duan Yuejiao , Aubart Kelly , Fang Yuhong , Zonis Rimma , Yang Liping , Hu Wenhao 
Published: June 2011

AbstractStructural modification of a recently developed PDF inhibitor by replacing the pyrrolidine functionality with 3‐methylenepyrrolidine leads to the discovery of derivatives (I) exhibiting better in vitro antibacterial activity than the reference compounds against drug‐resistant clinical isolates including MRSA, PRSP, and H.
ChemInform Abstract: Discovery of Indole Alkaloids with Cannabinoid CB1 Receptor Antagonistic Activity.
Authors: Kitajima Mariko , Iwai Masumi , Kikura‐Hanajiri Ruri , Goda Yukihiro , Iida Mitsuru , Yabushita Hisatoshi , Takayama Hiromitsu 
Published: June 2011

AbstractThe new compound (I) is isolated from Voacanga africana together with two known indole alkaloids.
ChemInform Abstract: Synthesis and Antitumor Activity of Novel Ribonucleosides with C‐5 OH Replaced by a Diaminopyrimidinyl Group.
Authors: Wang Kerang , Wu Ling , Qin Zhanbin , Yan Xinhao , Li Xiaoliu , Chen Hua , Zhang Pingzhu , Zhang Jinchao 
Published: June 2011

AbstractStepwise nucleophilic substitution reactions of ribonucleosides (I) with dichloropyrimidine (II), and fatty amines (IV) under microwave irradiation afford the novel ribonucleosides (V).
ChemInform Abstract: Synthesis of Antioxidant Flavonoid Derivatives.
Authors: Yanase Emiko , Jang Young P. , Nakanishi Koji 
Published: June 2011

AbstractQuercetin‐caffeic acid (Ia) and quercetin‐curcumin conjugate (Ib) are synthesized starting from quercetin or curcumin, respectively.
ChemInform Abstract: Periodic Mesoporous Hydridosilica — Synthesis of an “Impossible” Material and Its Thermal Transformation into Brightly Photoluminescent Periodic Mesoporous Nanocrystal Silicon‐Silica Composite.
Authors: Xie Zhuoying , Henderson Eric J. , Dag Oemer , Wang Wendong , Lofgreen Jennifer E. , Kuebel Christian , Scherer Torsten , Brodersen Peter M. , Gu Zhong‐Ze , Ozin Geoffrey A. 
Published: June 2011

AbstractMeso‐HSiO1.5 is synthesized by template‐directed self‐assembly of HSi(OEt)3 under aqueous acid‐catalyzed conditions from mixtures of Pluronic‐123 surfactant, NaCl, aqueous HCl, BuOH, and HSi(OEt)3 (room temperature, 12 h).
ChemInform Abstract: Antimicrobial Activity of a New Combination System of Benzimidazole and Various Azoles.
Authors: Oezkay Yusuf , Tunali Yagmur , Karaca Huelya , Isikdag Ilhan 
Published: June 2011

AbstractThe compounds (I) exhibit significant activity against Candida species, additional the compounds (Ia)‐(Ic) are recognized as non‐toxic.
ChemInform Abstract: Synthesis and Anticonvulsant Activity of New N‐Mannich Bases Derived from 5‐Cyclopropyl‐5‐phenyl‐hydantoins.
Authors: Byrtus Hanna , Obniska Jolanta , Czopek Anna , Kaminski Krzysztof 
Published: June 2011

AbstractThe compounds (I) are screened for their anticonvulsant activity using intraperitoneal maximal electroshock (MES) and subcutaneous pentylenetetrazole seizures tests on mice.
Experimental test of absorption flattening correction for circular dichroism of particle suspensions
Authors: Gerdova Anna , Kelly Sharon M. , Halling Peter 
Published: June 2011

AbstractThere are well established theoretical models for correction for absorption flattening of circular dichroism (CD) measurements on particle suspensions. However, these have not been directly tested experimentally. We describe a test system with the chiral tris(ethylenediamine)Co(III) complex dissolved in water trapped inside sephadex particles, suspended in 1‐butanol. Independent measurements of particle size distribution, volume fraction, and the absorbance of the suspension are used to calculate the required CD correction. The corrected CD signal is found to agree rather well with that for the same amount of Co‐complex dispersed uniformly throughout the sample cell. This holds for different particle volume fractions and Co‐complex concentrations inside the particles. The correction seems to work despite a substantial scattering contribution to the absorbance, which is not considered in the theoretical models. Chirality, 2011. © 2011 Wiley‐Liss, Inc.
Rheological Properties of Capsule Membranes
Authors: Leick Sabine , Degen Patrick , Rehage Heinz 
Published: June 2011

AbstractMithilfe der Spinning‐ und Squeezing‐Capsule‐Methode lassen sich die rheologischen Eigenschaften von Kapselmembranen charakterisieren. Anhand eines Kapselmodellsystems konnte gezeigt werden, dass der Einbau von Feststoffpartikeln in die Gelmembranen flüssig gefüllter Kapseln zu einer Steigerung der mechanischen Stabilität und Erhöhung der Elastizitätsmoduln führt. Durch Kombination beider Methoden konnte außerdem die zweidimensionale Querkontraktionszahl für das Kapselhüllmaterial bestimmt werden.
Capillary Forces in Suspensions: Rheological Features und Potential Applications
Authors: Koos Erin , Dittmann Jens , Willenbacher Norbert 
Published: June 2011

AbstractEs hat sich gezeigt, dass in Suspensionen Kapillarkräfte zwischen der dispersen und der kontinuierlichen Phase eine tragende Rolle bzgl. der rheologischen Eigenschaften spielen. Im Rahmen dieses Beitrages wird aufgezeigt, dass das rheologische Verhalten einer in der kontinuierlichen Phase dispergierten dispersen Phase deutlich durch die Zugabe einer geringen Menge (&&num;60; 1 %) nicht mit der Hauptphase mischbaren Zweitphase modifiziert werden kann, was auf Kapillarkräfte zurückzuführen ist. Diesen Effekt kann man sich nun zum gezielten Einstellen von Produkteigenschaften zu Nutze machen.
Supported single‐site catalysts for slurry and gas‐phase olefin polymerisation
Authors: Choi Yiyoung , Soares João B. P. 
Published: June 2011

AbstractEarly and late transition metal single‐site catalysts revolutionised the polyolefin manufacturing industry and research with their ability to make polymers with uniform microstructural properties. Several of these catalysts are currently used commercially to produce commodity and differentiated‐commodity resins. The key to their rapid success and industrial implementation resided in the fact that they could be used without major modifications in the polymerisation reactors that previously used heterogeneous Ziegler–Natta and Phillips catalysts. Since most of these industrial processes use slurry or gas‐phase reactors, the soluble single‐site catalysts must be supported on adequate carriers that ensure not only high activity, but also the formation of polymer particles with the proper morphology and bulk densities. In this article, we will review several methods used for supporting single‐site early and late transition metal catalysts on a variety of supports. © 2011 Canadian Society for Chemical Engineering
Process intensification of synthesis of magnetite using spinning disc reactor
Authors: Moharir Rupesh G. , Gogate Parag R. , Rathod Virendra K. 
Published: June 2011

AbstractAn instantaneous co‐precipitation reaction for the synthesis of magnetite particles has been investigated in conventional mechanically agitated reactor and novel spinning disc reactor (SDR) with an objective of process intensification. Characteristics of the particles have been analysed using Coulter Counter particle analyser. It has been observed that the particle size distribution is more uniform with overall lower power consumption in the SDR as compared to the conventional reactors. With a viewpoint of improving the synthesis process in terms of the obtained conversion levels in the SDR, effect of different operating parameters viz. rotational speed, diameter and type of the disc, flow rate of the reactants and the operating temperature on the synthesis process has also been investigated. It has been observed that the flow rate of the reactants as well as disc characteristics have a significant influence on the extent of conversion. Overall, it has been established that the SDR gives excellent particle size distribution characteristics as compared to the conventional approaches and hence results in process improvement/intensification for magnetite synthesis process at comparatively lower energy inputs.
Effects of acid treatment on adhesive performance of encapsulated aluminium pigments on plastic sheets
Authors: Pi P. H. , Chen J. , Chen K. , Cai Z. Q. , Zheng D. F. , Wen X. F. , Cheng J. , Yang Z. R. 
Published: June 2011

AbstractIn this study, aluminium pigments were encapsulated with hydroxyl group‐containing acrylic resin after surface acid treatment to enhance their adhesive performance in the paint film. The removal efficiency of fatty acid on surface of aluminium particles was studied by means of thermogravimetric analysis and the effect of acid treatment on adhesive performance of aluminium pigments encapsulated with hydroxyl group‐containing acrylic resin in the paint film was investigated by pulling‐off tests. It was found that fatty acid on surface of aluminium particles was removed efficiently by acid ethanol solution, and then hydroxyl group‐containing acrylic resin can be encapsulated onto the surface of the aluminium particles by chemisorptions. The encapsulated aluminium pigments have excellent adhesive performance in the paint film. © 2011 Canadian Society for Chemical Engineering
Struktur‐Eigenschafts‐Beziehungen in der Organischen Chemie
Authors: Graulich Nicole , Schreiner Peter R. 
Published: June 2011

AbstractEin Chemiestudium zählt mit zu den schwersten Studiengängen und die Quote der Studienabbrecher ist höher als in anderen Fächern. Diese Tatsache liegt zum einen an der hohen zeitlichen Belastung der Studierenden, aber auch am Fehlen geeigneter Lehrkonzepte. Um die Inhalte des Chemiestudiums neu zu definieren und handlungsfähiger für die Studierenden zu gestalten, müssen neue Forschungsergebnisse sinnvoll mit Basiskonzepten verknüpft werden. Durch die Basiskonzepte bietet uns die Chemie bereits ein erfolgreiches Ordnungsprinzip, das jedoch nicht in vollem Umfang genutzt wird, um neues Wissen zu integrieren. In diesem Artikel wird auf die Bedeutung von Struktur‐Eigenschafts‐Beziehungen in der Lehre der Organischen Chemie eingegangen. Wie sich im Hinblick darauf ein heuristischer Ansatz aus Ergebnissen der organisch‐chemischen Forschung entwickelte, soll anhand des Sechs‐Elektronenkonzepts dargestellt werden.
The Value of Admission HbA1c Level in Diabetic Patients With Acute Coronary Syndrome
Authors: Chan Chi Yuen , Li Ruijie , Chan Joseph Yat Sun , Zhang Qing , Chan Chin Pang , Dong Ming , Yan Bryan P. , Lam Yat‐Yin , Yu Cheuk‐Man 
Published: June 2011

AbstractBackground:Elevated admission glucose level is a strong predictor of short‐term adverse outcome in patients with acute coronary syndrome (ACS). However, the prognostic value of diabetic control (ie, hemoglobin A1c levels) in patients with ACS is still undefined.Hypothesis:Hemoglobin A1c level may predict short‐term outcome in patients with ACS.Methods:We conducted a retrospective study with prospective follow‐up in 317 diabetic patients with ACS. Patients were stratified into 2 groups based on HbA1c level, checked within 8 weeks of the index admission (optimal control group, HbA1c ≤7%; suboptimal control group, HbA1c >7%). All patients were followed up prospectively for major adverse cardiovascular events (MACE) and mortality for 6 months. Short‐term clinical outcomes were also compared between the 2 study groups.Results:In our cohort, 27.4%, 46.4%, and 26.2% patients had unstable angina, non–ST‐segment elevation myocardial infarction, and ST‐segment elevation myocardial infarction, respectively. In‐hospital mortality was similar in both HbA1c groups (3.37% vs 2.88%, P = 0.803). Six‐month MACE was also similar (26.40% vs 26.47%, P = 0.919). All‐cause mortality, cardiovascular mortality, symptom‐driven revascularization, rehospitalization for angina, and hospitalization for heart failure were also similar in both groups. The hazard ratios for 6‐month MACE and individual endpoints were also similar in both groups.Conclusions:This study suggests that HbA1c levels before admission are not associated with short‐term cardiovascular outcome in diabetic patients subsequently admitted with ACS. © 2011 Wiley Periodicals, Inc.The authors have no funding, financial relationships, or conflicts of interest to disclose.
Right Ventricular Systolic Pressure Assessed by Echocardiography: A Predictive Factor of Mortality in Patients With Scleroderma
Authors: Kiatchoosakun Songsak , Wongvipaporn Chaiyasith , Nanagara Ratanavadee , Hoit Brian D. 
Published: June 2011

AbstractBackground:Pulmonary arterial hypertension (PAH) is a well‐known complication of systemic sclerosis (SSc). Doppler echocardiographic screening for the detection of PAH (by measuring right ventricular systolic pressure [RVSP]) is therefore recommended for all patients with SSc. However, the validity of RVSP as a predictor of mortality in patients with SSc is not well established.Hypothesis:Doppler‐determined PAH identifies a high‐risk subset of patients with SSc with decreased survival.Methods:We performed echocardiography in 155 consecutive patients with SSc between May 2005 and July 2006 and tested the value of an RVSP level of ≥36 mm Hg to predict mortality. Cox proportional hazards model was used to examine the individual relationship between each variable and the mortality rate.Results:Tricuspid regurgitant jets for RVSP determination were quantified in 129 patients (82.6%), of which 47 (36.4%) had RVSP ≥36 mm Hg. The median follow‐up time was 34 months. The 1‐, 2‐, and 3‐year survival rates were significantly lower among SSc patients with RVSP ≥36 vs ≤36 mm Hg (82%, 78%, and 67% vs 98%, 90%, and 86%, respectively, P < 0.01 by Wilcoxon test). In a multivariate analysis including echocardiographic and clinical variables, only an RVSP ≥36 mm Hg and a New York Heart Association III/IV class were associated with increased mortality; the respective Cox hazard ratios were 2.22 (95% confidence interval [CI]: 1.01–4.89, P = 0.048) and 4.77 (95% CI: 2.09–10.90, P = 0.000).Conclusions:Our results indicate that Doppler RVSP identifies a high‐risk subset and supports the use of Doppler RVSP as a screening test in patients with SSc who may warrant early treatment of their PAH. © 2011 Wiley Periodicals, Inc.The authors have no funding, financial relationships, or conflicts of interest to disclose.
Electrocardiogram‐Based Predictors of Sudden Cardiac Death in Patients With Coronary Artery Disease
Authors: Liew Reginald 
Published: June 2011

AbstractCurrent recommendations on which patients with coronary artery disease (CAD) should be offered an implantable cardioverter defibrillator for the primary prevention of sudden cardiac death (SCD) rely heavily on the presence of depressed left ventricular ejection fraction. Because the majority of SCD victims with CAD have preserved left ventricular function, additional cardiac investigations are likely to play an increasing role in the risk stratification of CAD patients. A number of studies have demonstrated that certain parameters on the traditional 12‐lead electrocardiogram (ECG) and other ECG‐based investigations (such as signal‐averaged ECG, heart rate turbulence, T‐wave alternans) can provide important information on the underlying cardiac substrate abnormality that may predispose to ventricular arrhythmias and SCD. This article reviews some of the evidence for these ECG‐based tests as predictors of SCD in patients with CAD and addresses their advantages and limitations. © 2011 Wiley Periodicals, Inc.The author has no funding, financial relationships, or conflicts of interest to disclose.
Peripheral Arterial Disease—What Do We Need to Know?
Authors: Shanmugasundaram Madhan , Ram Vinny K. , Luft Ulrich C. , Szerlip Molly , Alpert Joseph S. 
Published: June 2011

AbstractPeripheral artery disease (PAD) results from progressive narrowing of arteries secondary to atherosclerosis and is defined as an Ankle Brachial Index of <0.9. PAD is highly prevalent and is an increasing burden on both the economy and the patient, especially given the rapid shift in demographics in the United States. Despite its prevalence and association with cardiovascular disease, PAD is still underdiagnosed and undertreated. This may, in part, be related to lack of recognition from the physician's side or paucity of evidence from clinical trials. It has been shown that medical therapy approved for cardiovascular disease is effective in the treatment of PAD and decreases cardiovascular events. Various revascularization strategies are also available for improving symptoms and quality of life in these patients, yet they are underutilized. In an attempt to increase its recognition, PAD has been considered a coronary artery disease equivalent. This article reviews the diagnosis and management of PAD. © 2011 Wiley Periodicals, Inc.The authors have no funding, financial relationships, or conflicts of interest to disclose.
Dye Removal from Colored Textile Wastewater by Poly(propylene imine) Dendrimer: Operational Parameters and Isotherm Studies
Authors: Hayati Bagher , Mahmoodi Niyaz Mohammad , Arami Mokhtar , Mazaheri Firoozmehr 
Published: June 2011

AbstractThis paper deals with the removal of textile dyes from aqueous solutions by poly(propylene imine) dendrimer (PPI). Direct red 80 (DR80), Acid Green 25 (AG25), Acid Blue 7 (AB7), and Direct Red 23 (DR23) were used as model dyes. The effects of operational parameters on dye removal such as dendrimer concentration, dye concentration, salt (inorganic anions), and pH have been studied at 25°C. The Langmuir and Freundlich isotherm models were investigated. In addition, dye desorption of dendrimer was studied. The results indicated that acidic pH supported the adsorption of dyes by dendrimer. Furthermore studies of dye concentration and salt effects exhibited that dye removal percentage by dendrimer was decreased. It was found that the isotherm data of DR80, AG25, and DR23 followed Langmuir isotherm and isotherm data of AB7 followed Freundlich isotherm models. Desorption tests showed that maximum dye releasing of 76.5% for DR80, 84.5% for AG25, 87% for AB7, and 93% for DR23 were achieved in aqueous solution at pH 12. Based on the data of present study, one could conclude that the dendrimer being an environmentally friendly adsorbent with relatively large adsorption capacity might be a suitable alternative for elimination of dyes from colored textile wastewater.
Biofiltration of Hexane Vapor: Experimental and Neural Model Analysis
Authors: Zamir Morteza , Halladj Rouein , Saber Mohammad , Ferdowsi Milad , Nasernejad Bahram 
Published: June 2011

AbstractBiofiltration is a commonly practiced biological technique to remove volatile compounds from waste gas streams. From an industrial view‐point, biofilter (BF) operation should be flexible to handle temperatures and inlet load (IL) variations. A compost BF was operated at different temperatures (30–45°C) and at various inlet loading rates (ILR; 8–598 g m−3 h−1) under intermittent loading conditions. Complete removal of n‐hexane was observed at 30 and 35°C at ILRs up to 330 g m−3 h−1. Besides, 20–75% of the pollutant was removed at 40°C, corresponding to the different ILs applied to the BF. Increasing the temperature to 45°C decreased the removal efficiency (RE) significantly. A feed forward neural network was used to predict the RE of BF with temperature and ILR as the input variables. The experimental data was divided into training (2/3) and test datasets (1/3). The best structure of neural network was obtained by trial and error on the basis of the least differences between predicted and experimental values, as ascertained from their coefficient of regression (R2) values. The modeling results showed that a multilayer network with the topology 2−10−1 was able to predict BF performance effectively with R2‐value of 0.995 for the test data. The results from this study showed the predicting capability of ANNs which can be considered as an alternative for conventional knowledge‐based models.