bluuebunny/crossref_metadata_2025_split huggingface dataset:
SNAP: Supportive non‐invasive ventilation for acute chest syndrome prevention for hospitalized children with sickle cell disease: Perspectives of patients, parents, and the healthcare team
Authors: Cohen Robyn T. , Burrowes Shana A. B. , Williams Christopher J. , Neri Caitlin M. , Klings Elizabeth S. , Jones Kayla C. , Walkey Allan J. , Drainoni Mari‐Lynn 
Published: June 2024

AbstractRationaleAcute chest syndrome (ACS) often develops during hospitalizations for sickle cell disease (SCD) vaso‐occlusive episodes and may be triggered by a combination of chest wall splinting, opioid use, hypoventilation, and atelectasis. In 2017, Boston Medical Center's general pediatric inpatient unit instituted the novel use of bi‐level positive airway pressure (BiPAP) as “supportive non‐invasive ventilation for ACS prevention” (SNAP) to prevent ACS and respiratory decompensation.ObjectiveThe goals of this qualitative study were to identify perceived benefits, harms, facilitators, and barriers to use of SNAP.MethodsWe conducted semi‐structured key informant interviews at three sites with different levels of SNAP implementation (Site 1: extensive implementation; Site 2: limited implementation; Site 3: not yet implemented) regarding experiences with and/or perceptions of SNAP. Interviews and coding were guided by the Promoting Action on Research Implementation in Health Services (PARiHS) framework.ResultsThirty‐four participants (physicians, nurses, respiratory therapists, child life specialists, psychologists, youth with SCD, and parents) completed interviews. Major themes included: (i) participants perceive BiPAP as effective at preventing ACS, and for those with medically stable ACS, for preventing respiratory decompensation. (ii) BiPAP use is appropriate on the general pediatric inpatient unit for medically stable patients with SCD. (iii) Improving the patient experience is the most important factor to optimize acceptance of BiPAP by patients and families.Conclusion/future directionsSNAP is perceived as effective and appropriate for hospitalized pediatric patients with SCD. Improving the patient experience is the biggest challenge. These data will inform a future protocol for a multicenter hybrid effectiveness/implementation trial of SNAP.
Psychological impact of the COVID‐19 pandemic on infertile patients: A systematic review and meta‐analysis
Authors: Liu Yu , Su Yiyao , Li Xiaoshan 
Published: June 2024

AbstractThe present study aimed to examine the psychological impact of the COVID‐19 pandemic on infertile patients. We adopted a comparison design and searched articles published from 1 September 2016 to 31 December 2019 as the control group, while articles published from 1 January 2020 to 31 April 2023 were treated as the pandemic group. Specifically, Web of Science, PubMed, Medline, PsycArticle, CNKI and PsycINFO were searched to identify potential eligible records. Risk of bias was assessed, and random‐effects meta‐analyses were conducted to estimate the prevalence of specific mental health problems. Forty studies with a total of 19,480 participants were included in the analysis. The pooled prevalence of anxiety in the pandemic group was significantly higher than that in the control group. The depression and stress prevalence in the pandemic group was higher than that in the control group, yet did not reach statistical significance. A subgroup analysis revealed region differences with developed countries exhibiting higher rates of anxiety and depression in the pandemic group, but the result was the opposite in the control group. Physiological factors, psychological factors and social factors correlated with infertile patients' mental health were identified. The COVID‐19 pandemic had a significant negative impact on infertile patients' mental health, emphasizing the importance of ways to mitigate the risks during the pandemic.
Validation and determining an optimal cut‐off score of the Infant Behavior Checklist for autism spectrum disorder
Authors: Takeda Toshinobu , Osada Hirokazu , Tsuji Yui , Kurita Hiroshi 
Published: June 2024

AbstractAimGiven the escalating prevalence of autism spectrum disorder (ASD), the persistent paucity of child psychiatrists in Japan, and the need to prepare for unforeseen situations, such as the COVID‐19 pandemic, it is essential to establish a reliable screening tool. This study aims to validate the Infant Behavior Checklist (IBC) developed by Japanese experts and determine its appropriate cut‐off score.MethodsA total of 354 clinic‐referred children, along with their caregivers, participated in this research. Clinical records, including diagnoses established through the sub‐structured diagnostic interviews, and the IBC assessments, were subjected to rigorous statistical analysis.ResultsAmong the 24 items, six failed to reach significance to differentiate ASD from non‐ASD cases. The Cronbach's alpha coefficient for the IBC was calculated at 0.77. The IBC total score for ASD cases was significantly higher than that of non‐ASD cases. With the chosen cut‐off score, the IBC demonstrated an area under the ROC curve of 0.803, along with sensitivity, specificity, positive predictive value, and negative predictive value of 8.03, 0.79, 0.69, 0.34, and 0.94, respectively.ConclusionThe IBC exhibits satisfactory internal consistency and content and discriminant validity. The high sensitivity and other associated indices for the optimal cut‐off score of the IBC affirm its validity as a screening instrument for ASD. Nevertheless, further investigations are warranted to ascertain the clinical utility of the IBC.
Extrusion‐printing additive manufacturing of composite solid propellant by fast curing isocyanated‐HTPB and HTPB blending‐extruded via a static mixer
Authors: Ren Liyuan , Jiang Licong , Chen Kang , Guo Qirui , Xiao Leqin , Zhou Weiliang 
Published: June 2024

AbstractThis article studied a novel method for extrusion‐printing additive manufacturing (AM) of composite solid propellant by fast curing isocyanated‐HTPB and HTPB, which were blended and extruded via a static mixer. The gel time and tack‐free time of isocyanated‐HTPB with HTPB or diamines were extensively studied to screen for the potential formulation of extrusion‐printing. Upon the results of computational fluid dynamics simulation on the mixing effect of the static mixer, the formulation with 7 min gel time and 2.5 h tack‐free time was selected for extrusion‐printing experiment. The shape retaining characteristic of the formulations with 72 wt %, 75 wt %, 80 wt %, and 85 wt % solid content was qualitatively studied by printing the points, fibers, fiber arrays, and multilayer samples under fixed printing parameters, such as the slurry flux, the nozzle moving speed, and air pressure etc. The results showed that the curing rate and solid content play an important role in the free standing property of the slurry printed. A 3D sample with a complex geometric shape, which has 15 layers,18.5 mm in height, and 20.1 mm in outer diameter, was successfully extrusion‐printed by fast curing the slurry with the formulation of 85 wt % solid content. Its tensile strength and elongation at break are 0.33 MPa and 39.9 %, respectively. SEM observation showed that the internal morphology of the sample printed is dense and uniform. The results demonstrated that extrusion‐printing AM by fast curing two components is a potential candidate AM method for composite solid propellants with high solid content.
Mutating the arginine residue within the FRNK motif of telosma mosaic virus (TelMV) HC‐Pro protein attenuates viral infection and confers effective protection against TelMV in passion fruit (Passiflora edulis)
Authors: Wang Linxi , Shi Wei , Aziz Asma , Wang Xiaoqing , Liu Haobin , Shen Wentao , Cui Hongguang , Dai Zhaoji 
Published: June 2024

AbstractBACKGROUNDTelosma mosaic virus (TelMV, Potyvirus, Potyviridae) is an emerging viral pathogen that threatens passion fruit plantations worldwide. However, an efficient strategy for controlling such a virus is not yet available. Cross protection is a phenomenon in which pre‐infection of a plant with one mild strain prevents or delays subsequent infection by the same or closely related virus. HC‐Pro is the potyviral encoded multifunctional protein involved in several steps of viral infection, including multiplication, movement, transmission and RNA silencing suppression. In this study, we tested whether it is possible to generate attenuated viral strains capable of conferring protection against severe TelMV infection by manipulating the HC‐Pro gene.RESULTSBy introducing point mutation into the conserved motif FRNK of HC‐Pro that is essential for RNA silencing suppression, we have successfully obtained three attenuated mutants of TelMV (R181K, R181D, and R181E, respectively). These attenuated TelMV mutants could systemically infect passion fruit plants without noticeable symptoms. Pre‐inoculation of one of these attenuated mutants confers efficient protection against subsequent infection by severe TelMV strain. Moreover, we demonstrated that the HC‐Pros harbored by the attenuated mutants exhibit reduced RNA silencing suppression activity in Nicotiana benthamiana leaves.CONCLUSIONThe attenuated TelMV mutants developed in this study that are suitable for cross protection offer a practical, powerful tool to fight against TelMV for sustainable passion fruit production. © 2024 Society of Chemical Industry.
Adjuvant use for the management of pesticide drift, leaching and runoff
Authors: Hewitt Andrew J 
Published: June 2024

AbstractAdjuvants are included in many pesticide spray mixtures to enhance the performance of the applied chemical. Many adjuvants which modify the emulsion or extensional viscosity of the tank‐mixture have been found to offer benefits in drift management, primarily by eliminating or reducing the ‘Fine’ droplets included in the spray with diameters <100–200 μm that can move off‐target in unfavorable conditions during ground, airblast and aerial pesticide applications. Among wind tunnel and field studies conducted around the world, there is consensus that while some adjuvants are effective for drift management, the performance varies on a case‐by‐case basis, requiring verification for each adjuvant which could be achieved through a programme such as certification based on showing a reduction in Fine droplets and/or a reduction in airborne drift. These can be measured in wind tunnel studies according to international standards. This article provides a review of the current science in this subject area, from the approaches to data collection to a review of existing data and regulatory application for encouraging and rewarding the use of appropriate adjuvants that have been demonstrated to reduce airborne spray drift potential and therefore the size of no‐spray buffer zones appropriate to protect nontarget sensitive areas from drift exposure. Some adjuvants can offer the same reduction in drift as offered by hooded sprayer retrofits. A drift reduction programme based on adjuvant use could include testing candidate adjuvants for their effect on droplet size and reduction in Fine droplets when sprayed through reference nozzles and compared against sprays without the adjuvant. Testing could also be based alternatively on measurements of drift potential on collectors such as monofilament line in wind tunnel or field studies. Once shown to be effective in reducing ‘Fines’ or spray drift, adjuvants could be certified and then referenced on pesticide labels and/or regulatory or best management practice schemes to encourage their use and offer reductions in use restrictions or no‐spray buffer zone sizes based on drift management. Studies have shown that some adjuvants can reduce pesticide leaching into soils and contamination of groundwater, as well as runoff of active ingredients from plants into the environment. Performance depends on the adjuvant type, the pesticide with which it is used, the soil or plant type, the timing and mass of water input from rainfall and climatic factors. © 2024 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
A case of pulmonary transthyretin amyloidosis with concurrent mycobacterial tuberculosis infection
Authors: Siu Hanson , Mond Ari , Shaw James , Chin Ruth , Hosking Patrick , Wimaleswaran Hari 
Published: June 2024

AbstractAmyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction. Pulmonary involvement is generally associated with immunoglobulin light chain type (AL) amyloid. Transthyretin (ATTR) amyloid build up in the lung is thought to be a senile disease observed usually as a finding at autopsy. We describe a case of pulmonary ATTR amyloidosis with concurrent mycobacterial tuberculosis infection.
Memory event‐triggered mechanism based switching‐like control for CPSs under DoS attack
Authors: Geng Qing , Li Jinling , Li Li 
Published: June 2024

SummaryIn this article, a memory event‐triggered mechanism (METM) based switching‐like control method is designed for a cyber‐physical system (CPS), maintain control performance and improve the communication efficiency under denial of service (DoS) attack. In order to obtain better control effect at small sampling periods, a sampler contains the explicit sampling period is designed by using delta operator approach. First of all, a METM based on an acknowledgement character (ACK) mechanism is proposed, which can reduce event triggered data calculations, increase the transmission instants at the crest or trough of the responses and reduce the negative impact of DoS attack. Next, a switching‐like control strategy for the delta operator system converted from the CPS is designed to prevent DoS attack resulting in open‐loop unstable operation of the system. Further, a switching law is designed to maintain the concealment of the secure channel. Then, sufficient conditions are derived for the CPS in terms of linear matrix inequalities (LMIs). Finally, the effectiveness of the designed method is verified by a simulation example.
Word Learning Opportunities in Preschool Storybook Apps
Authors: Bruner Lori 
Published: June 2024

AbstractIn this study, I examined preschool storybook apps for the affordances they may provide for young children's vocabulary development. Specifically, I sought to understand (a) the degree to which storybook apps introduce new words, (b) the types of words children can learn, and (c) the degree to which digital enhancements align with new words in the story. To do so, I conducted a content analysis of 26,744 words in 70 best‐selling storybook apps in the United States. Results indicate that approximately 7.5% of words in preschool storybook apps might be considered new words for preschool children—which is comparable to the number of new words in preschool printed books. Furthermore, approximately 25% of new words in storybook apps are aligned with digital enhancements. These findings contribute new information about vocabulary in preschool storybook apps and the extent to which digital enhancements might support children's word learning on screen.
In vitro Models for Predicting Bioadhesion Fracture Strength to Ex Vivo Animal Buccal Tissue
Authors: Rahamim Valeria Solomianski , Patel Dhaval , Drori Eliyahu , Coopersmith Sarah , Azagury Aharon 
Published: June 2024

AbstractCommitment to the 3Rs principle (Replacement, Reduction, and Refinement) led to the development of a cell‐based system to measure buccal bioadhesion in vitro and replace the use of porcine buccal and esophageal tissues (PBT and PET, respectively). Additionally, the aim is to bridge the gap in knowledge regarding the bioadhesion properties of PBT and PET. The in vitro models are based on the human buccal epithelial cell line—TR146 without (“Model I”) or with (“Model II”) 5% (w/v) mucous layer. The in vitro setup also provides a method to evaluate the bioadhesion between two soft materials. Standard bioadhesive hydrogels (alginate, chitosan, and gelatin) are used to test and compare the results from the in vitro models to the ex vivo tissues. The ex vivo and in vitro models show increased bioadhesion as the applied force and contact time increases. Furthermore, Model I exhibits bioadhesion values—of alginate, chitosan, and gelatin—comparable to those obtained with PBT. It is also found that contact time and applied force similarly affect PBT and PET bioadhesion, while PET exhibits greater values. In conclusion, Model I can replace PBT for measuring bioadhesion and be incorporated into the experimental design of bioadhesive DDS, thus minimizing animal tissue usage.
Tailoring Stress‐Relieved Structure for SnSe Toward High Performance Potassium Ion Batteries
Authors: Ren Naiqing , Li Xiaoying , Wang Lifeng , Si Juntao , Zeng Sihan , Liu Huaibing , He Haiyan , Chen Chunhua 
Published: June 2024

AbstractMetal chalcogenides as an ideal family of anode materials demonstrate a high theoretical specific capacity for potassium ion batteries (PIBs), but the huge volume variance and poor cyclic stability hinder their practical applications. In this study, a design of a stress self‐adaptive structure with ultrafine SnSe nanoparticles embedded in carbon nanofiber (SnSe@CNF) via the electrospinning technology is presented. Such an architecture delivers a record high specific capacity (272 mAh g−1 at 50 mA g−1) and high‐rate performance (125 mAh g−1 at 1 A g−1) as a PIB anode. It is decoded that the fundamental understanding for this great performance is that the ultrafine SnSe particles enhance the full utilization of the active material and achieve stress relief as the stored strain energy from cycling is insufficient to drive crack propagation and thus alleviates the intrinsic chemo‐mechanical degradation of metal chalcogenides.
Reconfigurable Resistive Switching Memory for Telegraph Code Sensing and Recognizing Reservoir Computing Systems
Authors: Kim Dohyung , Truong Phuoc Loc , Lee Cheong Beom , Bang Hyeonsu , Choi Jia , Ham Seokhyun , Ko Jong Hwan , Kim Kyeounghak , Lee Daeho , Park Hui Joon 
Published: June 2024

AbstractReservoir computing (RC) system is based upon the reservoir layer, which non‐linearly transforms input signals into high‐dimensional states, facilitating simple training in the readout layer—a linear neural network. These layers require different types of devices—the former demonstrated as diffusive memristors and the latter prepared as drift memristors. The integration of these components can increase the structural complexity of RC system. Here, a reconfigurable resistive switching memory (RSM) capable of implementing both diffusive and drift dynamics is demonstrated. This reconfigurability is achieved by preparing a medium with a 3D ion transport channel (ITC), enabling precise control of the metal filament that determines memristor operation. The 3D ITC‐RSM operates in a volatile threshold switching (TS) mode under a weak electric field and exhibits short‐term dynamics that are confirmed to be applicable as reservoir elements in RC systems. Meanwhile, the 3D ITC‐RSM operates in a non‐volatile bipolar switching (BS) mode under a strong electric field, and the conductance modulation metrics forming the basis of synaptic weight update are validated, which can be utilized as readout elements in the readout layer. Finally, an RC system is designed for the application of reconfigurable 3D ITC‐RSM, and performs real‐time recognition on Morse code datasets.
Capture–translocation restores spawning migration connectivity of Razorback Suckers in the fragmented San Juan River
Authors: Bogaard Matthew R. , Gido Keith B. , McKinstry Mark C. , Pennock Casey A. , Barkalow Adam , Bonjour Sophia M. , Bowman Jerrod , Creighton Katherine C. , Hines Brian A. , Schleicher Benjamin J. 
Published: June 2024

Abstract

Objective
Barriers to movement negatively affect population vital rates of riverine fishes that rely on connected migratory routes to complete components of their life cycle, such as reproduction and recruitment. In the southwestern United States, decades of water diversion, construction of large impoundments, and loss of floodplain habitats have all contributed to highly fragmented riverscapes. A capture–translocation strategy was implemented for Razorback Suckers Xyrauchen texanus in the San Juan River to mitigate the negative effects of two barriers while precluding the upstream movement of nonnative species. We hypothesized that translocated individuals would remain upstream of barriers during the spawning season and that aggregations of translocated Razorback Suckers would be identified upstream in spawning habitats.

Methods
We used radiotelemetry to assess movement of Razorback Suckers after translocation above the two barriers. We deployed fixed remote radio receivers to determine residency time above each barrier and conducted mobile telemetry surveys to monitor upstream destinations after translocation.

Result
Although most Razorback Suckers returned downstream of barriers within 2 months of translocation, we provide evidence that most individuals remained upstream long enough to successfully spawn. After translocation above the Piute Farms Waterfall, 80% of individuals remained upstream for 26 days in 2020 and for 23 days in 2021. Further upstream (307 km), at a weir operated by the Public Service Company of New Mexico, 80% of translocated individuals remained above the barrier for 37 days in 2021 and for 25 days in 2022. After fish translocation above both barriers, we observed upstream movements ranging from 2 to 262 km and we detected distinct aggregations within the expected spawning season.

Conclusion
Although translocation efforts seasonally reconnect migratory routes for a proportion of the population and may increase spawning potential, other conservation actions are likely still needed to improve recruitment conditions for juvenile fish.
First detection of tick‐borne encephalitis virus (TBEV) in raw milk samples in North‐Western Iran
Authors: Parsadanians Angineh , Mirshahabi Hessam , Yavarmanesh Masoud 
Published: June 2024

AbstractTick‐borne encephalitis virus (TBEV) is a significant cause of flaviviral infections affecting the human central nervous system, primarily transmitted through tick bites and the consumption of unpasteurized milk. This study aimed to assess the prevalence of TBEV and identify new natural foci of TBEV in livestock milk. In this cross‐sectional study, unpasteurized milk samples were collected from livestock reared on farms and analysed for the presence and subtyping of TBEV using nested reverse transcription‐polymerase chain reaction , alongside the detection of anti‐TBEV total IgG antibodies using ELISA. The findings revealed that the highest prevalence of TBEV was observed in goat and sheep milk combined, whereas no TBEV was detected in cow milk samples. All identified strains were of the Siberian subtype. Moreover, the highest prevalence of anti‐TBEV antibodies was detected in sheep milk. These results uncover new foci of TBEV in Iran, underscoring the importance of thermal processing (pasteurization) of milk prior to consumption to mitigate the risk of TBEV infection.
The InSecTT Reference Architecture
Authors: Samano-Robles Ramiro 
Published: June 2024

AbstractThis chapter presents an overview of the Reference Architecture (RA) of the project InSecTT. The chapter makes emphasis on the impact generated by the new AI (Artificial Intelligence) algorithms and their associated building blocks (BBs) on standard architectures for IoT. The chapter focuses on the main views or perspectives of the architecture, on how AI interacts with each one of these perspectives and in the end we provide two examples of use case alignment and the analysis of the impact of AI on the individual architectures.