bluuebunny/crossref_metadata_2025_split huggingface dataset:
Osseointegrated Implant Fracture: Causes and Treatment
Authors: Gealh Walter Cristiano , Mazzo Valéria , Barbi Francisco , Camarini Edevaldo Tadeu 
Published: June 2010

Abstract
Despite its high success rate, therapy with osseointegrated dental implants is not free of complications. Among the problems that may occur is fracture of implants, which, albeit a rare phenomenon, may lead to unpleasant clinical outcomes for the patient, as well as for the clinician. Thus, it is paramount to know the factors related to the biological processes involved in maintenance of osseointegration and biomechanics applied to dental implants to prevent such complications, as well as treatment options available to deal with the problem. Therefore, the objectives of this work were to investigate the literature to identify causative factors that may lead to fracture of dental implants and to discuss available procedures.
Spiral Implants Bearing Full-Arch Rehabilitation: Analysis of Clinical Outcome
Authors: Danza Matteo , Grecchi Francesco , Zollino Ilaria , Casadio Claudia , Carinci Francesco 
Published: June 2010

Abstract
A spiral implant (SPI) is a conical internal helix implant with a variable thread design which confers the characteristic of self drilling, self tapping, and self bone condensing. The effectiveness of this type of implant has been reported in several clinical situations. However, because there are no reports that specifically focus on one of the biggest challenges in oral rehabilitation, that is, full arch rehabilitation, it was decided to perform a retrospective study. The study population was composed of 23 patients (12 women and 11 men, median age 57 years) for evaluation and implant treatment between January 2005 and June 2009. Two-hundred six spiral family implants (SFIs) were inserted with a mean postloading follow-up of 23 months. Several variables were investigated: demographic (age and gender), anatomic (maxilla and mandible, tooth site), implant (type, length, and diameter), surgical (surgeon, postextractive, flapless technique, grafts), and prosthetic (implant/crown ratio, dentition in the antagonist arch, type of loading, and computerized tomography [CT] planning) variables. Implant loss and peri-implant bone resorption were evaluated. Univariate and multivariate tests were performed. Survival and success rates were 97.1% and 82.5%, respectively. Only implant length and implant/crown ratio showed statistical significance in determining a better clinical outcome. In conclusion, SFIs are a reliable tool for the most difficult cases of oral rehabilitation. No differences were detected among implant type. Length and implant/crown ratio can influence the crestal bone resorption with better result for longer fixtures and a higher implant/crown ratio. In addition, banked bone derived from living donors can be used to restore alveolar ridge augmentation without adverse effects. Finally, flapless and CT-planned surgery did not significantly increase the clinical outcome in most complex rehabilitation.
Dental Implant Rehabilitation of a Patient With Down Syndrome: A Case Report
Authors: Ribeiro Cleide Gisele , Siqueira Aline Franco , Bez Leonardo , Cardoso Antônio Carlos , Ferreira Cimara Fortes 
Published: June 2010

Abstract
Implant-supported rehabilitations show higher patient satisfaction when compared with conventional prostheses. Systemic conditions, however, can affect treatment planning of dental implant supported rehabilitations. The oral structures that are commonly affected in patients with Down syndrome include the tongue (macroglossia), teeth (number and shape), and poor quality alveolar and jaw bones (osteoporotic-like). This clinical case presents an interdisciplinary team approach aimed at achieving functional, phonetic, and esthetic outcomes in a patient with Down syndrome.
Bone Repair in Periodontal Defect Using a Composite of Allograft and Calcium Sulfate (DentoGen) and a Calcium Sulfate Barrier
Authors: Mazor Ziv , Mamidwar Sachin , Ricci John L. , Tovar* Nick M. 
Published: June 2010

Abstract
Deep bone defects are caused by the progression of periodontal disease, which breaks down bone and connective tissue that hold teeth in place. In this case, a 37-year-old male patient presented a deep bone defect with advanced periodontal disease around an upper canine. Medical-grade calcium sulfate was mixed with demineralized freeze-dried bone allograft and used to repair and regenerate the defect. Analysis of the radiographs at the 5-month time point showed the bone had completely regenerated.
Precision Attachment Case Restoration With Implant Abutments: A Review With Case Reports
Authors: Feinberg Edward 
Published: June 2010

Abstract
Passively retained precision attachment partial dentures have been used successfully on natural tooth abutments since the 1920s. However, the dental profession has not advocated their use with implant abutments. When used in the passive manner that has proven successful on natural tooth abutments, precision attachment cases on implant abutments can be an excellent treatment option. This type of case has been used successfully for more than 17 years and offers tremendous advantages over the conventional overdenture approach to removal restorations on implant abutments.
Comparison of Delayed Implant Placement vs Immediate Implant Placement Using Resonance Frequency Analysis: A Pilot Study on Rabbits
Authors: Kunnekel Ashish T. , Dudani Mohit T. , Nair Chandrasekharan K. , Naidu E. M. , Sivagami G. 
Published: June 2010

Ten identical implants were equally divided into 2 groups. In the immediate placement (control) group, implants were placed immediately following osteotomy preparation, and in the delayed placement (test) group, implants were placed 2 weeks following osteotomy preparation, in rabbit femurs. Implant stability quotient values for both groups were measured using resonance frequency analysis immediately following placement and at day 40. Results were statistically analyzed and indicate that delayed placement of implants leads to faster rates of osseointegration.
Effect of Patient Age on Management Decisions in Breast Cancer: Consensus from a National Consultation
Authors: Leonard Robert C. , Barrett-Lee Peter J. , Gosney Margot A. , Willett Alexis M. , Reed Malcolm W. , Hammond Pauline J. 
Published: June 2010

Abstract
This qualitative study investigated the attitudes, perceptions, and practices of breast cancer specialists with reference to the effect of patient age on management decisions in breast cancer, and attempted to identify national consensus on this issue. One hundred thirty-three relevant specialists, including 75 surgeons and 43 oncologists, participated in a virtual consultation using e-mailed questionnaires and open-ended discussion documents, culminating in the development of proposed consensus statements sent to participants for validation. A strong consensus was seen in favor of incorporating minimum standards of diagnostic services, treatment, and care for older patients with breast cancer into relevant national guidance, endorsed by professional bodies. Similarly, an overwhelming majority of participants agreed that simple, evidence-based protocols or guidelines on standardizing assessment of biological and chronological age should be produced by the National Institute for Health and Clinical Excellence and the Scottish Medicines Consortium, developed in collaboration with specialist oncogeriatricians, and endorsed by professional bodies. A further recommendation that all breast cancer patient treatment and diagnostic procedures be undertaken in light of up-to-date, relevant scientific data met with majority support. This study was successful in gauging national specialist opinion regarding the effect of patient age on management decisions in breast cancer in the U.K.
Homocysteinethiolactone and Paraoxonase
Authors: Barathi Subramaniam , Angayarkanni Narayanasamy , Pasupathi Aarthi , Natarajan Sulochana Konerirajapuram , Pukraj Rishi , Dhupper Maneesh , Velpandian Thirumurthy , Muralidharan Charanya , Sivashanmugham Muthukumaran 
Published: June 2010

OBJECTIVE
Paraoxonase (PON) exhibits esterase activity (PON-AREase) and lactonase activity (PON-HCTLase), which prevent LDL oxidation and detoxify homocysteine thiolactone (HCTL). The role of HCTL and PON-HCTLase as a risk factor for the microvascular complication in diabetic retinopathy at the level of vitreous has not been investigated.

RESEARCH DESIGN AND METHODS
Undiluted vitreous from patients with proliferative diabetic retinopathy (PDR) (n = 13) and macular hole (MH) (n = 8) was used to determine PON-HCTLase and PON-AREase activity spectrophotometrically. HCTL levels were detected by liquid chromatography–tandem mass spectrometry. In vitro studies were done in primary cultures of bovine retinal capillary endothelial cells (BRECs) to determine the dose- and time-dependent effect of HCTL and homocysteine (Hcys) on PON-HCTLase activity, as well as to determine mRNA expression of PON by RT-PCR.

RESULTS
A significant increase in HCTL and PON-HCTLase activity was observed in PDR compared with MH (P = 0.036, P = 0.001), with a significant positive correlation between them (r = 0.77, P = 0.03). The in vitro studies on BRECs showed a dose- and time-dependent increase in the PON-HCTLase activity and mRNA expression of PON2 when exposed to HCTL and Hcys.

CONCLUSIONS
This is the first study showing elevated levels of vitreous HCTL and PON-HCTLase activity in PDR. These elevations are probably a protective effect to eliminate HCTL, which mediates endothelial cell dysfunction. Thus, vitreous levels of HCTL and PON activity can be markers of diabetic retinopathy. The bioinformatics analysis reveals that the structure and function of PON that can be modulated by hyperhomocysteinemia in PDR can affect the dual-enzyme activity of PON.
Polyendocrinopathy in Children, Adolescents, and Young Adults With Type 1 Diabetes
Authors: Warncke Katharina , Fröhlich-Reiterer Elke E. , Thon Angelika , Hofer Sabine E. , Wiemann Dagobert , Holl Reinhard W. ,   on behalf of the DPV Initiative of the German Working Group for Pediatric Diabetology and the German BMBF Competence Network for Diabetes Mellitus
Published: June 2010

OBJECTIVE
To investigate diabetes-specific autoantibodies and additional autoimmune phenomena in a large cohort of young patients with type 1 diabetes.

RESEARCH DESIGN AND METHODS
Data from 28,671 patients &lt;30 years with type 1 diabetes from 242 specialized centers in Germany and Austria were analyzed.

RESULTS
At least one β-cell antibody was present in 81.6% of patients. β-cell–Ab-negative patients were significantly younger at diabetes onset (P &lt; 0.0001). A total of 19.6% had positive thyroid antibodies with female predominance (62%, P &lt; 0.0001). Antibodies to tissue transglutaminase were present in 10.7%, with a significantly longer duration of diabetes (P &lt; 0.0001). Parietal cell antibodies were found in 283 patients, associated with older age (P &lt; 0.001), and adrenal antibodies were present in 94 patients. In 575 patients, at least three different autoimmune phenomena were present.

CONCLUSIONS
Thyroid autoimmunity and antibodies suggestive for celiac disease are the most prevalent additional immune phenomena in type 1 diabetes. Parietal/adrenal antibodies are rare.
Increased CD36 Expression Signals Monocyte Activation Among Patients With Type 2 Diabetes
Authors: Sun Yijuan , Scavini Marina , Orlando Robert A. , Murata Glen H. , Servilla Karen S. , Tzamaloukas Antonios H. , Schrader Ronald , Bedrick Edward J. , Burge Mark R. , Abumrad Nada A. , Zager Philip G. 
Published: June 2010

OBJECTIVE
To explore the hypothesis that CD36, a scavenger receptor and fatty acid translocase, is upregulated in peripheral blood mononuclear cells (PBMCs) among patients with type 2 diabetes and is a biomarker of PBMC activation and inflammation.

RESEARCH DESIGN AND METHODS
We used a cross-sectional observational design to study a multi-racial/ethnic population sample consisting of Caucasians, Hispanics, and Native Americans with type 2 diabetes (n = 33) and nondiabetic control subjects (n = 27). PBMC CD36 mRNA/protein and plasma high sensitivity (hs) C-reactive protein (hsCRP), hs–interleukin-6 (hsIL-6), and adiponectin were measured.

RESULTS
Unadjusted PBMC CD36 mRNA and protein were 1.56- and 1.63-fold higher, respectively, among type 2 diabetic subjects versus control subjects. PBMC CD36 protein was directly associated with CD36 mRNA, plasma hsCRP, and hsIL-6 and inversely associated with plasma adiponectin in both groups.

CONCLUSIONS
Increased CD36 expression is a biomarker of PBMC activation and inflammation and may become a useful tool in cardiovascular disease risk stratification.
Pain Management: Part 1: Managing Acute and Postoperative Dental Pain
Authors: Becker Daniel E. 
Published: June 2010

Abstract
Safe and effective management of acute dental pain can be accomplished with nonopioid and opioid analgesics. To formulate regimens properly, it is essential to appreciate basic pharmacological principles and appropriate dosage strategies for each of the available analgesic classes. This article will review the basic pharmacology of analgesic drug classes, including their relative efficacy for dental pain, and will suggest appropriate regimens based on pain intensity. Management of chronic pain will be addressed in the second part of this series.
Hydrogen sorption characteristics of magnesium-based composites with addition of Mg2Ni0.7Co0.3 and graphite
Authors: Grigorova E. , Khristov M. , Khrussanova M. 
Published: June 2010

Abstract
Magnesium-based composites of 75 wt% Mg — (10, 15, 20) wt% Mg2Ni0.7Co0.3 — (15, 10, 5) wt% C mechanically activated for 30 min under argon in a planetary mill, were obtained. Their absorption-desorption characteristics were investigated under a pressure P = 1 MPa and temperatures of 623, 573, 473, 423 and 373 K. Desorption was carried out at 623 K and 573 K and a pressure of 0.15 MPa. All the three composites showed improved hydriding kinetics as compared to pure magnesium. However, the desorption temperature was somewhat higher than needed for practical application.
The protection of Nifedipin from photodegradation due to complex formation with β-cyclodextrin
Authors: Nikolić Vesna , Ilić Dušica , Nikolić Ljubiša , Stanković Mihajlo , Cakić Milorad , Stanojević Ljiljana , Kapor Agneš , Popsavin Mirjana 
Published: June 2010

Abstract
The inclusion complex β-cyclodextrin:nifedipin was prepared in solid state by coprecipitation with 1:1 mol ratio. The structure of the obtained complex and nifedipin was characterized by use of X-ray diffraction (XR), infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and differential scanning calorimetry (DSC) methods. The photodegradation of nifedipin and the β-cyclodextrin:nifedipin inclusion complex in solid state was monitored under natural daylight by infrared spectroscopy, whereby the free nifedipin degraded four to five times faster than the complexed nifedipin. The photodegradation products of both free and complexed nifedipin, formed during irradiation at 350 nm (with corresponding energy flux of 18 W m−2) were monitored by liquid chromatography during various time intervals. The speed of formation of nitroso- and nitro-phenyl derivatives by nifedipin irradiation was significantly higher than those of complexed nifedipin irradiation, which indicates its increased photostability in the inclusion complex. The effect on this property is significant because it contributes both to the improvement of the therapeutic effect of nifedipin and to the safer application thereof.
Facile preparation of graphite intercalation compounds in alkali solution
Authors: Li Jihui , Shi Huiqing , Li Ning , Li Mei , Li Jing 
Published: June 2010

Abstract
Graphite intercalation compounds are often prepared by flake graphite, oxidants, inorganic acids, organic acids and intercalated ions which are usually hydrogen protons between the graphene planes. They are also known as the acid-treated graphite intercalation compounds. In this work, alkaline graphite intercalation compounds were prepared by flake graphite, K2Cr2O7, concentrated H2SO4 and NaOH, and the morphology and structure were characterized by Electron microscopy and X-ray techniques. The results display that the combination of neutralisation heat and oxidation capability produced by K2Cr2O7 can break the bonds to produce the spaces between the graphene planes and hydroxyl ions also intercalate into the graphene planes to form alkaline graphite intercalation compounds in alkali solution. The morphology and structure of alkaline graphite intercalation compounds are analogous to the ones of the acid-treated graphite intercalation compounds, but the intercalated ions and the expansion volume are different. The results show that the method is an innovation.
Protolytic properties of the structurally rigid analogs of 2,6-distyrylpyridine. Widening the pH sensitivity range by the photochemical E→Z isomerisation and introduction of substituents capable to protolytic interactions
Authors: Grygorovych Oleksiy , Nevskii Oleksiy , Moskalenko Sofia , Pivovarenko Vasyl , Doroshenko Andrey 
Published: June 2010

Abstract
Protolytic interactions in the series of prospective fluorescent ratiometric wide-range pH indicators — structurally rigid analogs of 2,6-distyrylpyridine — (3E,5E)-3,5-dibenzylidene-8-phenyl-1,2,3,5,6,7-hexahydrodicyclopentano[b,e]pyridine — were investigated. The pyridine nitrogen atom basicity in these compounds is significantly lower in comparison with that of unsubstituted heterocycle and 2,6-distyrylpyridine. The photochemical E→Z photoisomerization and the side benzene rings substituents influence on the acid-base equilibria were studied. The complex multi-stage mechanism of the acid-base interactions of the polysubstituted compounds was elucidated. The most significant spectral effects were typical to the N,N-dialkylamino substituted compounds of the investigated series. The widest pH sensitivity interval covering nearly the full range of 0–14 units was demonstrated for compounds with both proton donor and proton acceptor substituents.
Capillary electrophoretic separation and characterizations of CdSe quantum dots
Authors: Oszwałdowski Sławomir , Zawistowska Katarzyna , Grigsby Laura , Roberts Kenneth 
Published: June 2010

Abstract
We have developed a capillary electrophoresis method to characterize the QD surface ligand interactions with various surfactant systems. The method was demonstrated with 2–5 nm CdSe nanoparticles surface-passivated with trioctylphosphine oxide (TOPO). Water solubility was accomplished by surfactant-assisted phase transfer via an oil-in-water microemulsion using either cationic, anionic, or non-ionic surfactants. Interaction between the QD surface ligand (TOPO) and the alkyl chain of the surfactant molecule produces a complex and dynamic surface coating that can be characterized through manipulation of CE separation buffer composition and capillary surface modification. Additional characterization of the QD surface ligand interactions with surfactants was accomplished by UV-VIS spectroscopy, photoluminescence, and TEM. It is anticipated that studies such as these will elucidate the dynamics of QD surface ligand modifications for use in sensors.
One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides to N-alkyl-2-(2-hydroxyphenyl)-2-imino-acetamides
Authors: Ghandi Mehdi , Asgari Parham , Taheri Abuzar , Abbasi Alireza 
Published: June 2010

Abstract
One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides is reported. N-alkyl-2-(2-hydroxyphenyl)-2-iminoacetamide derivatives are generated presumably via the preliminary formation of N, N′-disubstituted benzo[b]furan-2,3-diamines and subsequent oxidation with molecular oxygen.
Complex formation reactions of palladium(II)-1,3-diaminopropane with various biologically relevant ligands. Kinetics of hydrolysis of glycine methyl ester through complex formation
Authors: El-Sherif Ahmed , Shoukry Mohamed , El-Bahnasawy Ramadan , Ahmed Dalia 
Published: June 2010

Abstract
The interaction of [Pd(DAP)(H2O)2]2+ (DAP = 1,3-diaminopropane) with some selected bio-relevant ligands, containing different functional groups, were investigated. The ligands used are dicarboxylic acids, amino acids, peptides and DNA constituents. Stoichiometry and stability constants of the complexes formed are reported at 25°C and 0.1 M ionic strength. The results show the formation of 1:1 complexes with amino acids and dicarboxylic acids. The effect of chelate ring size of the dicarboxylic acid complexes on their stability constants is examined. Peptides form both 1:1 complexes and the corresponding deprotonated amide species. DNA constituents form 1:1 and 1:2 complexes. The effect of dioxane on the acid dissociation constants of CBDCA and the formation constant of its complex with Pd(DAP)2+ was reported. The kinetics of hydrolysis of glycine methyl ester bound to [Pd(DAP)(H2O)2]2+ was studied at 25°C and 0.1M ionic strength.
An ab initio simulation of the UV/Visible spectra of substituted chalcones
Authors: Xue Yunsheng , Mou Jie , Liu Yi , Gong Xuedong , Yang Yihua , An Lin 
Published: June 2010

Abstract
The electronic absorption spectra of 29 phenyl-ring substituted chalcones have been investigated with the time-dependent density functional theory (TD-DFT) and polarizable continuum TD-DFT (PCM-TD-DFT). It turns out that the hybrid PBE1PBE functional with the 6-31G basis set provide reliable λmax when the solvent effects are included in the model. Comparisons with experimental values lead to a mean absolute error of 12 nm (0.136 eV). Moreover, the observed substituent effects are reproduced by calculation qualitatively. The λmax of substituted chalcone in phenyl ring A is less sensitive to substitution than that in ring B. The linear correlation of Hammett’s substituent constants (σP) with LUMO energies is better with respect to HOMO energies. The calculation reveals that the maximum absorption band mainly results from the π→π* transition from HOMO to LUMO. The analysis of the electron density plots of frontier molecular orbitals show that most transitions should be of valence excitation nature.
Spectroscopic evaluation of chiral and achiral fluorescent ionic liquids
Authors: Marwani Hadi 
Published: June 2010

Abstract
In this study, spectroscopic investigation of chiral and achiral room temperature ionic liquids is achieved. New ionic liquids were prepared via metathesis, accomplished by the reaction of either L-phenylalanine ethyl ester hydrochloride, chlorpromazine hydrochloride or 1,10-Phenanthroline monohydrate hydrochloride with lithium bis(trifluoromethane) sulfonamide in water. The resulting ionic liquids were produced in high yield and purity. The results obtained by use of 1H NMR and IR experiments were in very good agreement with the chemical structures of the synthesized ionic liquids. In addition, the results of thermal gravimetric analysis suggested that these ionic liquids have good thermal stability. UV-Vis and fluorescence spectroscopy measurements indicated that these ionic liquids are strongly optically absorbent and fluorescent. Lastly, time-based fluorescence steady-state measurements demonstrated the high photostability of these ionic liquids.
Silica hybrid biomaterials containing gelatin synthesized by sol-gel method
Authors: Chernev Georgi , Borisova Borislava , Kabaivanova Lyudmila , Salvado Isabel 
Published: June 2010

Abstract
This work reports the sol-gel synthesis of silica hybrids. We determined the effect of the type and quantity of silica precursors and organic compounds on the resulting structure, surface area, nanostructure design and size, and potential applications. The structure of the synthesized hybrids was analyzed using FT-IR, XRD, BET-Analysis, SEM, and AFM. We demonstrate the immovilization of whole living thermophilic bacterial cells with cyanocompound degradation activity in the synthesized silica hybrid biomaterials by entrapment, chemical binding, and adsorption.