bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improved vascular depiction and image quality through deep learning reconstruction of CT hepatic arteriography during transcatheter arterial chemoembolization
Authors: Tanahashi Yukichi , Kubota Koh , Nomura Takayuki , Ikeda Takanobu , Kutsuna Masaya , Funayama Satoshi , Kobayashi Tatsunori , Ozaki Kumi , Ichikawa Shintaro , Goshima Satoshi 
Published: June 2024

Abstract
Purpose
To evaluate the effect of deep learning reconstruction (DLR) on vascular depiction, tumor enhancement, and image quality of computed tomography hepatic arteriography (CTHA) images acquired during transcatheter arterial chemoembolization (TACE).

Methods
Institutional review board approval was obtained. Twenty-seven patients (18 men and 9 women, mean age, 75.7 years) who underwent CTHA immediately before TACE were enrolled. All images were reconstructed using three reconstruction algorithms: hybrid-iterative reconstruction (hybrid-IR), DLR with mild strength (DLR-M), and DLR with strong strength (DLR-S). Vascular depiction, tumor enhancement, feeder visualization, and image quality of CTHA were quantitatively and qualitatively assessed by two radiologists and compared between the three reconstruction algorithms.

Results
The mean signal-to-noise ratios (SNR) of sub-segmental arteries and sub-sub-segmental arteries, and the contrast-to-noise ratio (CNR) of tumors, were significantly higher on DLR-S than on DLR-M and hybrid-IR (P < 0.001). The mean qualitative score for sharpness of sub-segmental and sub-sub-segmental arteries was significantly better on DLR-S than on DLR-M and hybrid-IR (P < 0.001). There was no significant difference in the feeder artery detection rate of automated feeder artery detection software among three reconstruction algorithms (P = 0.102). The contrast, continuity, and confidence level of feeder artery detection was significantly better on DLR-S than on DLR-M (P = 0.013, 0.005, and 0.001) and hybrid-IR (P < 0.001, P = 0.002, and P < 0.001). The weighted kappa values between two readers for qualitative scores of feeder artery visualization were 0.807–0.874. The mean qualitative scores for sharpness, granulation, and diagnostic acceptability of CTHA were better on DLR-S than on DLR-M and hybrid-IR (P < 0.001).

Conclusions
DLR significantly improved the SNR of small hepatic arteries, the CNR of tumor, and feeder artery visualization on CTHA images. DLR-S seems to be better suited to routine CTHA in TACE than does hybrid-IR.
Narcissism on display? Effects of full-shot and medium-shot photographs posted on social media on tourists’ attraction visit interest
Authors: Tan Wee-Kheng , Dong Jia-You 
Published: June 2024

AbstractThrough theory of narcissism and leisure constraint theory, this study considers how tourists’ vulnerable narcissism facets and lack of interest travel constraint at destination level affect their interest in attractions after viewing social media photographs of other visitors posed as full shot or medium shot (photograph types). Partial least-squares analysis on 614 survey returns (307 for full-shot and 307 for medium-shot photographs) revealed vulnerable narcissism’s impact on attraction visit interest is mostly evident in wenqing attractions. Lack of interest constraint lowers natural and monument attraction visit interest but not for wenqing attractions. Only entitlement rage facet positively influences lack of interest constraint.
Thermodynamic Assessments of Ti-Al, Ti-Fe, and Ti-Al-Fe Systems with Four-Sublattice Description of Ordered Body-Centered Cubic Phase and Density Functional Theory Data
Authors: Liang Zhi , Kattner Ursula , Choudharry Kamal , Tavazza Francesca , Campbell Carelyn 
Published: June 2024

AbstractA thermodynamic description of the Ti-Al-Fe system was established with reassessed Ti-Al and Ti-Fe binary systems using density function theory (DFT) data. All stable and metastable end members of BCC_B2, BCC_D03/B32, BCC_L21, inverse BCC_L21, Laves C14, D019-Ti3Al, L10-TiAl, Ti Al2, Ti3Al5, D022-TiAl3, τ2 and τ3 in the Ti-Al, Ti-Fe and Ti-Al-Fe systems were energetically defined with available experimental data and DFT calculations, reaching reasonable consistency. The ternary description was used to successfully calculate the A2-B2-L21 transformation in Fe-rich corner and A2-B2 transformation in Ti-rich corner, allowing the design of Ti-rich and Fe-rich alloys in this system.
Synergistic Impact of Pomegranate Peel Extract and High Hydrostatic Pressure on Controlling Discolouration and Oxidation in Iberian Dry Sausage Throughout Storage
Authors: R. Cava , I. Montero , L. Ladero 
Published: June 2024

AbstractThis study aimed to assess the impact of high-pressure processing and the inclusion of a pomegranate peel extract (PPE) on colour, antioxidant residual activities and lipid and protein oxidation of dry-cured and uncured sausages during 120 days of refrigerated storage. Nitrite and PPE were added into the sausage formulations following four treatments: (1) 150 mg/kg NaNO2 (C_Pos), (2) 0 mg/kg NaNO2 (C_Neg), (3) 0 mg/kg NaNO2 + 1% PPE (PPE1) and (4) 0 mg/kg NaNO2 + 2% PPE (PPE2). The four dry sausage batches were divided into two groups, one left untreated (0.1 MPa) and the other subjected to high hydrostatic pressure treatment (600 MPa, 8 min). The results revealed significant differences in the initial oxidation levels, with nitrite removal leading to increased lipid peroxidation and protein carbonylation. The pomegranate extract surpasses nitrite in the amount of residual antioxidant activity in the sausages and was comparable to nitrites in controlling lipid and protein oxidation. Despite this, thiols were affected, decreasing their value in batches with added pomegranate extract. Finally, the colour of the dry sausages varied significantly towards more yellowish and less reddish when the pomegranate extract was added.
Specific microbiome patterns and their association with breast cancer: the intestinal microbiota as a potential biomarker and therapeutic strategy
Authors: Amaro-da-Cruz Alba , Rubio-Tomás Teresa , Álvarez-Mercado Ana I. 
Published: June 2024

Abstract
Breast cancer (BC) is one of the most diagnosed cancers in women. Based on histological characteristics, they are classified as non-invasive, or in situ (tumors located within the milk ducts or milk lobules) and invasive. BC may develop from in situ carcinomas over time. Determining prognosis and predicting response to treatment are essential tools to manage this disease and reduce its incidence and mortality, as well as to promote personalized therapy for patients. However, over half of the cases are not associated with known risk factors. In addition, some patients develop resistance to treatment and relapse. Therefore, it is necessary to identify new biomarkers and treatment strategies that improve existing therapies. In this regard, the role of the microbiome is being researched as it could play a role in carcinogenesis and the efficacy of BC therapies. This review aims to describe specific microbiome patterns associated with BC. For this, a literature search was carried out in PubMed database using the MeSH terms “Breast Neoplasms” and “Gastrointestinal Microbiome”, including 29 publications. Most of the studies have focused on characterizing the gut or breast tissue microbiome of the patients. Likewise, studies in animal models and in vitro that investigated the impact of gut microbiota (GM) on BC treatments and the effects of the microbiome on tumor cells were included. Based on the results of the included articles, BC could be associated with an imbalance in the GM. This imbalance varied depending on molecular type, stage and grade of cancer, menopause, menarche, body mass index, and physical activity. However, a specific microbial profile could not be identified as a biomarker. On the other hand, some studies suggest that the GM may influence the efficacy of BC therapies. In addition, some microorganisms and bacterial metabolites could improve the effects of therapies or influence tumor development.
Bent functions satisfying the dual bent condition and permutations with the $$(\mathcal {A}_m)$$ property
Authors: Polujan Alexandr , Pasalic Enes , Kudin Sadmir , Zhang Fengrong 
Published: June 2024

Abstract
The concatenation of four Boolean bent functions

$$f=f_1||f_2||f_3||f_4$$

f
=

f
1

|
|

f
2

|
|

f
3

|
|

f
4

is bent if and only if the dual bent condition

$$f_1^* + f_2^* + f_3^* + f_4^* =1$$

f
1
∗

+

f
2
∗

+

f
3
∗

+

f
4
∗

=
1

is satisfied. However, to specify four bent functions satisfying this duality condition is in general quite a difficult task. Commonly, to simplify this problem, certain relations between

$$f_i$$

f
i

are assumed, as well as functions

$$f_i$$

f
i

of a special shape are considered, e.g.,

$$f_i(x,y)=x\cdot \pi _i(y)+h_i(y)$$

f
i

(
x
,
y
)

=
x
·

π
i

(
y
)

+

h
i

(
y
)

are Maiorana-McFarland bent functions. In the case when permutations

$$\pi _i$$

π
i

of

$$\mathbb {F}_2^m$$

F
2
m

have the

$$(\mathcal {A}_m)$$

(

A
m

)

property and Maiorana-McFarland bent functions

$$f_i$$

f
i

satisfy the additional condition

$$f_1+f_2+f_3+f_4=0$$

f
1

+

f
2

+

f
3

+

f
4

=
0

, the dual bent condition is known to have a relatively simple shape allowing to specify the functions

$$f_i$$

f
i

explicitly. In this paper, we generalize this result for the case when Maiorana-McFarland bent functions

$$f_i$$

f
i

satisfy the condition

$$f_1(x,y)+f_2(x,y)+f_3(x,y)+f_4(x,y)=s(y)$$

f
1

(
x
,
y
)

+

f
2

(
x
,
y
)

+

f
3

(
x
,
y
)

+

f
4

(
x
,
y
)

=
s

(
y
)

and provide a construction of new permutations with the

$$(\mathcal {A}_m)$$

(

A
m

)

property from the old ones. Combining these two results, we obtain a recursive construction method of bent functions satisfying the dual bent condition. Moreover, we provide a generic condition on the Maiorana-McFarland bent functions

$$f_1,f_2,f_3,f_4$$

f
1

,

f
2

,

f
3

,

f
4

stemming from the permutations of

$$\mathbb {F}_2^m$$

F
2
m

with the

$$(\mathcal {A}_m)$$

(

A
m

)

property, such that the concatenation

$$f=f_1||f_2||f_3||f_4$$

f
=

f
1

|
|

f
2

|
|

f
3

|
|

f
4

does not belong, up to equivalence, to the Maiorana-McFarland class. Using monomial permutations

$$\pi _i$$

π
i

of

$$\mathbb {F}_{2^m}$$

F

2
m

with the

$$(\mathcal {A}_m)$$

(

A
m

)

property and monomial functions

$$h_i$$

h
i

on

$$\mathbb {F}_{2^m}$$

F

2
m

, we provide explicit constructions of such bent functions; a particular case of our result shows how one can construct bent functions from APN permutations, when m is odd. Finally, with our construction method, we explain how one can construct homogeneous cubic bent functions, noticing that only very few design methods of these objects are known.
1H, 13C and 15N backbone resonance assignment of Cel45A from Phanerochaete chrysosporium
Authors: Okmane Laura , Sandgren Mats , Ståhlberg Jerry , Nestor Gustav 
Published: June 2024

AbstractA glycoside hydrolase family 45 (GH45) enzyme from the white-rot basidiomycete fungus Phanerochaete chrysosporium (PcCel45A) was expressed in Pichia pastoris with 13C and 15N labelling. A nearly complete assignment of 1H, 13C and 15N backbone resonances was obtained, as well as the secondary structure prediction based on the assigned chemical shifts using the TALOS-N software. The predicted secondary structure was almost identical to previously published crystal structures of the same enzyme, except for differences in the termini of the sequence. This is the first NMR study using an isotopically labelled GH45 enzyme.
The East China Sea: A Case of Ocean Geopolitics and Maritime Conflict
Authors: Midford Paul , Østhagen Andreas 
Published: June 2024

AbstractThis article analyzes ECS maritime disputes through two lenses: as a globally comparable case study mediated through LOS and as a distinct regional case that differs in several respects from disputes outside East Asia. This study focuses on the Senkaku/Diaoyu island dispute but also examines broader EEZ and ADIZ disputes between China, Japan, and South Korea and the Ieodo dispute between China and South Korea. It finds that global dynamics are applicable to the ECS disputes, as countries depend on LOS rules even while attempting to interpret them for unilateral advantage whenever possible, and parties avoid formal arbitration, when possible, in favor of bilateral agreements. However, regional factors impact these dynamics. The sudden and sometimes violent transition from the Sino-Centric tributary system to the Westphalian system has undermined the legitimacy of LOS and western international law regionally. Finally, the presence of China as a party to almost all ECS disputes limits the application of LOS because China’s position as a near-peer competitor with the US gives it additional options to unilaterally impose its will. Unlike relatively weaker parties to these disputes, China may be less concerned about flouting LOS that it does not see as necessary for protecting its maritime claims.
Assessing the impact of immunotherapy on oncolytic virotherapy in the treatment of cancer
Authors: Omer Salaheldin , Mambili-Mamboundou Hermane 
Published: June 2024

AbstractCombined oncolytic virotherapy and immunotherapy are novel treatment protocols that represent a promising and advantageous strategy for various cancers, surpassing conventional anti-cancer treatments. This is due to the reduced toxicity associated with traditional cancer therapies. We present a mathematical model that describes the interactions between tumor cells, the immune response, and the combined application of virotherapy and interleukin-2 (IL-2). A stability analysis of the model for both the tumor and tumor-free states is discussed. To gain insight into the impact of model parameters on tumor cell growth and inhibition, we perform a sensitivity analysis using Latin hypercube sampling to compute partial rank correlation coefficient values and their associated p-values. Furthermore, we perform optimal control techniques using the Pontryagin maximum principle to minimize tumor burden and determine the most effective protocol for the administered treatment. We numerically demonstrate the ability of combined virotherapy and IL-2 to eliminate tumors.
Numerical simulation and experimental validation of microstructure evolution during the upsetting process of a large size martensitic stainless steel forging
Authors: Dourandish Simin , Champliaud Henri , Morin Jean-Benoit , Jahazi Mohammad 
Published: June 2024

AbstractThe microstructure evolution, plastic deformation, and damage severity during the open die hot forging of a martensitic stainless steel were investigated using finite element (FE) simulation. A microstructure evolution model was developed and combined with a visco-elastoplastic model to predict the strain, the strain rate, and the temperature distribution, as well as the volume fraction and the size of dynamically recrystallized grains over the entire volume of an industrial size forging. The propensity to damage during hot forging was also evaluated using the Cockcroft & Latham model. The three models were implemented in the FE code and the results analyzed in terms of microstructure inhomogeneity and stress levels in different regions of the forging. A good agreement was obtained between the predicted and the experimental results, demonstrating that the simulation provided a realistic representation of the forging process at the industrial scale.
A Community-Partnered Research Process for Implementation Strategy Design: Developing Resources to Support Behavioral Classroom Interventions
Authors: Lawson Gwendolyn M. , Owens Julie Sarno , Mandell David S. , Tavlin Samantha , Rufe Steven , Depa Aubrey , Lyon Aaron R. , Power Thomas J. 
Published: June 2024

AbstractSchools need effective, sustainable implementation strategies to support teachers in using effective Tier 1 (i.e., whole class) and Tier 2 (i.e., targeted) behavioral interventions in the classroom. This paper describes an iterative, community-partnered process of developing implementation resources to support teachers in using Tier 1 and 2 positive behavior management interventions; we call these resources the Positive Behavior Management Toolkit (PBMT). There were two key aspects to the iterative development process: 1) working with a Program Development Team of district—and school-employed partners to identify priorities, interpret data, provide feedback on resources, and plan for sustainment; and 2) conducting a series of tryouts in which teachers used a version of the PBMT in their classrooms and provided quantitative and qualitative feedback on acceptability, appropriateness, feasibility, and recommendations for improvement. In partnership with the Program Development Team, we used data from the tryouts to inform revisions to the PBMT. This paper presents quantitative and qualitative data from the tryouts and describes how these data informed revisions to the PBMT. We also describe the processes by which we engaged the team, considerations related to contextual appropriateness, and lessons learned related to community-engaged intervention development research.
Existence results of $$\text {Spin}(2, n - 1)_0$$-pseudo-Riemannian cobordisms
Authors: Bais Valentina , Custodio Victor Gustavo May , Torres Rafael 
Published: June 2024

AbstractIn this note, we study necessary and sufficient conditions for the existence of a Spin$$(n + 1)$$

(
n
+
1
)

-dimensional cobordism that supports a non-singular and non-degenerate pseudo-Riemannian metric of signature $$(2, n - 1)$$

(
2
,
n
-
1
)

, which restricts to a non-singular time-orientable Lorentzian metric on its boundary. The corresponding cobordism groups are computed.
On the Connection Between Irrationality Measures and Polynomial Continued Fractions
Authors: Ben David Nadav , Nimri Guy , Mendlovic Uri , Manor Yahel , De la Cruz Mengual Carlos , Kaminer Ido 
Published: June 2024

AbstractLinear recursions with integer coefficients, such as the recursion that generates the Fibonacci sequence $${F}_{n}={F}_{n-1}+{F}_{n-2}$$

F
n

=

F

n
-
1

+

F

n
-
2

, have been intensely studied over millennia and yet still hide interesting undiscovered mathematics. Such a recursion was used by Apéry in his proof of the irrationality of $$\zeta \left(3\right)$$

ζ

3

, which was later named the Apéry constant. Apéry’s proof used a specific linear recursion that contained integer polynomials (polynomially recursive) and formed a continued fraction; such formulas are called polynomial continued fractions (PCFs). Similar polynomial recursions can be used to prove the irrationality of other fundamental constants such as $$\pi$$
π
and $$e$$
e
. More generally, the sequences generated by polynomial recursions form Diophantine approximations, which are ubiquitous in different areas of mathematics such as number theory and combinatorics. However, in general it is not known which polynomial recursions create useful Diophantine approximations and under what conditions they can be used to prove irrationality. Here, we present general conclusions and conjectures about Diophantine approximations created from polynomial recursions. Specifically, we generalize Apéry’s work from his particular choice of PCF to any general PCF, finding the conditions under which a PCF can be used to prove irrationality or to provide an efficient Diophantine approximation. To provide concrete examples, we apply our findings to PCFs found by the Ramanujan Machine algorithms to represent fundamental constants such as $$\pi$$
π
, $$e$$
e
, $$\zeta \left(3\right)$$

ζ

3

, and the Catalan constant. For each such PCF, we demonstrate the extraction of its convergence rate and efficiency, as well as the bound it provides for the irrationality measure of the fundamental constant. We further propose new conjectures about Diophantine approximations based on PCFs. Looking forward, our findings could motivate a search for a wider theory on sequences created by any linear recursions with integer coefficients. Such results can help the development of systematic algorithms for finding Diophantine approximations of fundamental constants. Consequently, our study may contribute to ongoing efforts to answer open questions such as the proof of the irrationality of the Catalan constant or of values of the Riemann zeta function (e.g., $$\zeta \left(5\right)$$

ζ

5

).
Still Higher Risk for Burnout and Low Work Engagement Among Female Residents After 10 Years of Demographic Feminisation
Authors: Kramer Maud , Könings Karen D. , Prins Jelle T. , van der Heijden Frank M. M. A. , Heyligers Ide C. 
Published: June 2024

Abstract
Objectives
We explored whether gender differences in burnout and work engagement characteristics among residents changed after the representation of female physicians has surpassed the 30% threshold of critical mass between 2005 and 2015, as well as if these gender differences are influenced by working in a surgical versus a non-surgical specialty.

Methods
This study used data of two questionnaire surveys on the well-being of Dutch residents, collected in 2005 (N = 2115) and 2015 (N = 1231). Burnout was measured with the validated Dutch translation of the Maslach Burnout Inventory, covering the characteristics emotional exhaustion, depersonalisation and personal accomplishment. Work engagement was measured with the Utrecht Work Engagement Scale, covering the characteristics vigour, dedication and absorption. Gender differences in residents’ engagement and burnout characteristics in 2005 and 2015 were analysed using hierarchical regression analyses. Factorial analyses of variance were used to compare gender differences in residents’ burnout and engagement characteristics in general surgery with those in internal medicine.

Results
In both years, female residents reported higher emotional exhaustion, lower depersonalisation, personal accomplishment, and vigour than males. These gender differences were similar in general surgery and internal medicine.

Conclusions
This study demonstrated unchanged gender differences in burnout and work engagement characteristics among residents after 10 years of demographic feminisation (increasing female representation), indicating higher risk for burnout and lower work engagement among females, both in surgical and non-surgical specialties. In view of the ever-increasing number of female residents, educators and hospitals need to create supporting work environments that safeguard residents’ well-being.
Transformation Behaviors and Microstructure Modifications in Hydrogen-Charged Ti–Ni Shape Memory Alloy
Authors: Kalbekov Alimzhan , Akamine Hiroshi , Ajito Saya , Akiyama Eiji , Hata Satoshi , Nishida Minoru 
Published: June 2024

AbstractThe effect of hydrogen charging duration on the transformation behavior, microstructural evolution, and dynamic microstructural changes associated with thermoelastic martensitic transformation in Ti–Ni shape memory alloy was investigated. Compared with the uncharged specimen, the martensitic transformation start (Ms) and reverse transformation finish (Af) temperatures increased with charging time, whereas the martensitic transformation finish and reverse transformation start temperatures remained almost unchanged. In situ SEM results were consistent with these behaviors. Upon cooling, the transformation progressed from the center to the surface in charged specimens, indicating a higher transformation temperature in the center than the surface. The latent heat of transformation decreased with increasing charging time, quantitatively attributed to an untransformed region consisting of hydrogen-induced martensite and a hydrogen-affected layer. The hydrostatic effect from those layers on the interior B2 phase was proposed as the origin of the increased Ms and Af temperatures.