bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Kejadian Computer Vision Syndrome dan Faktor Risikonya pada Mahasiswa FKM UI di Masa Pandemi Covid-19 Tahun 2022
Authors: Shadik Rahadian Muhammad , Widanarko Baiduri 
Published: April 2024

Akibat adanya pandemi Covid-19, banyak kegiatan yang tadi nya dilakukan secara offline, berubah menjadi daring, termasuk dalam sektor pendidikan. Hal ini mengakibatkan durasi penggunaan alat elektronik dengan layar digital/VDT meningkat, khususnya di kalangan mahasiswa. Durasi penggunaan layar digital/VDT ini merupakan salah satu faktor risiko dari Computer Vision Syndrome (CVS). Selain dari durasi, diduga ada beberapa faktor risiko lain yang juga berhubungan dengan CVS. Tujuan dilakukannya penelitian ini adalah untuk melihat gambaran kejadian CVS dan faktor risikonya, serta menganalisis hubungan antara kejadian CVS dan faktor risikonya pada mahasiswa (S1 Reguler dan pascasarjana S2) FKM UI di masa pandemi Covid-19 tahun 2022. Penelitian ini dilakukan pada bulan Maret-Juni 2022 dengan menggunakan kuesioner CVS-Q dan beberapa pertanyaan singkat terkait faktor risiko yang disebar secara online. Desain studi yang digunakan pada penelitian ini adalah cross-sectional dan melibatkan 250 responden yang berasal dari mahasiswa S1 reguler dan pascasarjana S2 FKM UI. Hasil dari penelitian ini menunjukkan terdapat 6 variabel yang mempunyai hubungan yang signifikan, yaitu usia (P= 0,000), durasi penggunaan layar digital/VDT(P= 0,006), pola istirahat (P= 0,007), kelainan refraksi mata(P= 0,014), penggunaan antiglare (P= 0,011), dan screen brightness (P= 0,030 ). Oleh karena itu, dibutuhkan pengendalian dan intervensi lebih lanjut agar masalah tersebut dapat diatasi.
Comparative studies of traditional methods and modern technological approaches in the pedagogy of the educational system of the People's Republic of China
Authors: Гурниковский А.И. , Гурниковская Р.Ю. 
Published: April 2024

сравнительное изучение традиционных методов обучения игре на скрипке, а также современных технологических подходов в педагогической деятельности с младшими школьниками Китайской Народной Республики является важной задачей. В настоящем исследовании нами был проведён анализ этих двух разных подходов к обучению игре на скрипке. Нами был изучен исторический опыт преподавания игры на скрипке в КНР, а также проанализированы современные цифровые технологии, которые начали активно использоваться в музыкальном образовании последние 10 лет. Была проанализирована доступная нам научная литература по данной теме. Полученные нами результаты показали, что традиционные методы обучения игре на скрипке с младшими школьниками в КНР до сих пор широко используются, однако современные цифровые технологии могут значительно облегчить обучение и сделать его более интересным и доступным для большего числа детей.
a comparative study of traditional methods of teaching violin playing, as well as modern technological approaches in teaching activities with younger schoolchildren of the People's Republic of China is an important task. In this study, we analyzed these two different approaches to learning to play the violin. We studied the historical experience of teaching violin playing in China, as well as analyzed modern digital technologies that have been actively used in music education over the past 10 years. The scientific literature available to us on this topic was analyzed. Our results showed that traditional methods of teaching violin playing to younger schoolchildren in China are still widely used, but modern digital technologies can greatly facilitate learning and make it more interesting and accessible to more children.
A pilot study on the development and testing of a method of musical psychoregulation of breathing in children with chronic bronchopulmonary pathology (from retrospect to perspective)
Authors: Лазарев М.Л. 
Published: April 2024

в статье описан метод восстановительного лечения детей 5-14 лет, страдающих хронической бронхолегочной патологией (бронхиальной астмой, астматическим бронхитом, хроническим бронхитом), названный методом музыкальной психорегуляции дыхания – методом МПД. Метод заключается в сознательном регулировании ребенком сначала отдельных функциональных звеньев своего дыхания (ритм, глубина, релаксация), а затем функционального системокомплекса через вокально-речевую деятельность и игру на детских духовых инструментах. В ходе осуществления метода, ребенок занимается эмоционально-дыхательным тренингом в процессе вокально-речевой деятельности и дыхательной музыкотерапии, сопровождаемым адаптивной гимнастикой (движение, закаливание). В ходе проведения исследования установлено, что метод МПД способствует очистке легких от мокроты, укреплению мышц бронхов, диафрагмы, передней брюшной стенки, повышению психоэмоционального тонуса, дает длительную и стойкую ремиссию.
the article describes a method of restorative treatment of children aged 5-14 years suffering from chronic bronchopulmonary pathology (bronchial asthma, asthmatic bronchitis, chronic bronchitis), called the method of musical psychoregulation of breathing – the MPB method. The method consists in consciously regulating the child's individual functional units of his breathing (rhythm, depth, relaxation), and then the functional system complex through vocal and speech activity and playing children's wind instruments. During the implementation of the method, the child is engaged in emotional and respiratory training in the process of vocal and speech activity and respiratory music therapy, accompanied by adaptive gymnastics (movement, hardening). During the study, it was found that the MPB method helps to clear the lungs of sputum, strengthen the muscles of the bronchi, diaphragm, anterior abdominal wall, increase psycho-emotional tone, and gives a long and stable remission.
The possibilities of using modern interactive equipment in the educational process of preschool educational institutions
Authors: Гордеева В.В. , Мустафаева П.Э. 
Published: April 2024

в статье рассматривается вопрос применения интерактивного оборудования в образовательном процессе детского сада. Одной из инноваций, применяемой в настоящее время в детском саду, является интерактивное оборудование, которое выступает неотъемлемой частью работы с воспитанниками дошкольного возраста. В статье описывается несколько видов интерактивного оборудования, которое можно использовать в дошкольных образовательных организациях, а также описываются режимы его функционирования, виды игр и заданий для дошкольников.
the article discusses the use of interactive equipment in the educational process of a kindergarten. One of the innovations currently used in kindergarten is interactive equipment, which is an integral part of working with preschool children. The article describes several types of interactive equipment that can be used in preschool educational organizations, as well as describes the modes of its operation, types of games and tasks for preschoolers.
The importance of physical fitness of traffic police officers of the Ministry of Internal Affairs of Russia in performing professional tasks (for example Oryol region)
Authors: Носов С.А. , Алдошин А.В. , Лапшин И.Е. , Малявина А.Б. , Степанова И.А. 
Published: April 2024

в данной научной статье «значимость физической подготовленности сотрудников ГИБДД МВД России при выполнении профессиональных задач (на примере Орловской области)», которая раскрывает вопросы о проблеме физической подготовки сотрудников ГИБДД. Сотрудник ГИБДД должен обладать не только основами и умениями практического применения огнестрельного оружия, но и боевыми приемами борьбы, так как в ходе защиты от ударов, либо при освобождении от захватов и охватов, а также при задержании правонарушителя, могут возникнуть такие ситуации, при которых сотруднику полиции важно владеть приемами борьбы в партере. Целью исследования является выявить проблемы стороны в общей физической подготовленности сотрудников ГИБДД МВД России и способы их повышения. Объектом исследования является общая физическая подготовленность сотрудник ГИБДД. Субъектом исследования являются инспектора ГИБДД УМВД России по Орловской области от 22 до 45 лет. Задачи исследования: 1. Определить исходные данные физической подготовленности сотрудников; 2. Разработать комплекс упражнений, которые поспособствуют к повышению физической подготовленности инспекторов ГИБДД; 3. Контрольная проверка на определении эффективности комплексных упражнений способствующие к повышению ОФП.
in this scientific article "The importance of physical fitness of traffic police officers of the Ministry of Internal Affairs of Russia in performing professional tasks (on the example of the Oryol region)", which reveals questions about the problem of physical training of traffic police officers. A traffic police officer must possess not only the basics and skills of practical use of firearms, but also combat fighting techniques, since during protection from blows, or when releasing from seizures and embraces, as well as when detaining an offender, situations may arise in which it is important for a police officer to master fighting techniques in the stalls. The purpose of the study is to identify the problems of the party in the general physical fitness of traffic police officers of the Ministry of Internal Affairs of Russia and ways to improve them. The object of the study is the general physical fitness of a traffic police officer. The subject of the study are inspectors of the traffic police of the Ministry of Internal Affairs of Russia in the Orel region from 22 to 45 years old. Research objectives: 1. To determine the initial data on the physical fitness of employees; 2. To develop a set of exercises that will contribute to improving the physical fitness of traffic police inspectors; 3. A control check to determine the effectiveness of complex exercises contributing to an increase in OFP.
Formation of paremiological competence of Korean students using dictionary materials
Authors: Квон Ж. 
Published: April 2024

в статье представлена концепция кросс-культурной репрезентации материала в учебном словаре пословиц для корейских студентов-русистов, а также система работы со словарной статьей, обеспечивающая формирование паремиологической компетенции студентов. Обосновывается принцип отбора материала и параметрическая модель словарной статьи. Ее параметрические зоны соотнесены с формированием определенных параметров паремиологической компетенции, к которым относятся: языковые знания о структуре и значении пословиц; понимание их культурного фона – связи с русской историей, традициями, обычаями народа; навыки распознавания пословиц в речи; навыки употребления пословиц в соответствующих коммуникативных ситуациях. Особое внимание уделяется структурированию лексикографического блока, включающего корейский паремиологический и культурологический материал. Этот блок формирует межкультурный компонент паремиологической компетенции корейских студентов-русистов: навыки сопоставительного анализа, подбора межъязыковых эквивалентов, лингвокультурологического комментирования корейских пословиц на русском языке. Это особенно важно с точки зрения профессиональной подготовки студентов, которые могут быть не только преподавателями русского языка как иностранного, но и переводчиками. Результаты экспериментальной работы со словарными статьями доказали эффективность разработанной лексикографической модели и предлагаемой системы работы со словарными материалами на занятиях по русскому языку.
the article presents the concept of cross-cultural representation of material in the educational dictionary of proverbs for Korean students of Russian studies, as well as a system for working with dictionary entries that ensures the formation of paremiological competence of students. The principle of material selection and the parametric model of the dictionary entry are substantiated. Its parametric zones are correlated with the formation of certain parameters of paremiological competence, which include: linguistic knowledge of the structure and meaning of proverbs; understanding their cultural background - connections with Russian history, traditions, customs of the people; skills of recognizing proverbs in speech; skills of using proverbs in appropriate communicative situations. Particular attention is paid to the structuring of the lexicographic block, which includes Korean paremiological and cultural material. This block forms the intercultural component of the paremiological competence of Korean Russian students: skills of comparative analysis, selection of interlingual equivalents, linguocultural commentary of Korean proverbs in Russian. This is especially important from the point of view of professional training of students, who can be not only teachers of Russian as a foreign language, but also translators. The results of experimental work with dictionary entries proved the effectiveness of the developed lexicographic model and the proposed system for working with dictionary materials in Russian language classes.
Density of cannabis outlets vs. cannabis use behaviors and prevalent cannabis use disorder: findings from a nationally-representative survey
Authors: Wichaidit Wit , Chapakiya Ilham , Waeuseng Aneesah , Chumchuen Kemmapon , Assanangkornchai Sawitri 
Published: April 2024

Background
Thailand recently decriminalized (de facto legalized) cannabis use and sales. However, nationally representative data are scarce with regard to cannabis use behaviors and its association with cannabis outlet density. The objectives of this study are: (1) to describe the prevalence of cannabis use behaviors and cannabis use disorder among the general adult population of Thailand; (2) to describe the extent that the density of cannabis outlets is associated with cannabis use behaviors, cannabis use disorder, and the amount of cannabis smoked per day.

Methods
We conducted a community-based cross-sectional study in 11 provinces and the Bangkok Metropolitan Area. Participants were residents of sampled communities aged 20 years or older. We requested literate participants to self-administer the questionnaire and interviewed participants who could not read. We analyzed data using descriptive statistics with sampling weight adjustments and multivariate logistic regression analyses.

Results
The prevalence of current cannabis use was 15 percent. At a 400-m radius, participants who reported three cannabis outlets had 4.2 times higher odds of being current users than participants who reported no outlet (Adjusted OR = 4.82; 95% CI [3.04–7.63]). We found no association between outlet density and hazardous cannabis use or cannabis use disorder, nor association with the amount of cannabis use among cannabis smokers.

Discussion and Conclusion
The patterns of association between outlet density and cannabis use behaviors were inconsistent. Furthermore, limitations regarding outlet density measurement and lack of temporality should be considered as caveats in the interpretation of the study findings.
Viral structural transition mechanisms revealed by multiscale molecular dynamics/order parameter extrapolation simulation
Authors: Miao Yinglong , Ortoleva Peter J. 
Published: September 2009

AbstractOn the basis of an all‐atom multiscale analysis theory of nanosystem dynamics, a multiscale molecular dynamics/order parameter extrapolation (MD/OPX) approach has recently been developed. It accelerates MD for long‐time simulation of large bionanosystems and addresses rapid atomistic fluctuations and slowly varying coherent dynamics simultaneously. In this study, MD/OPX is optimized and implemented to simulate viral capsid structural transitions. Specifically, 200 ns MD/OPX simulation of the swollen state of cowpea chlorotic mottle virus capsid reveals that it undergoes significant energy‐driven shrinkage in vacuum, which is a symmetry‐breaking process involving local initiation and front propagation. © 2009 Wiley Periodicals, Inc. Biopolymers 93: 61–73, 2010.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Peptidomimetics – A Versatile Route to Biologically Active Compounds
Authors: Grauer Andreas , König Burkhard 
Published: September 2009

AbstractProteins are vital for basically every known organism. Therefore the investigation of their structure, the development of a deeper understanding of protein–protein interactions and the design of novel peptides, which selectively interact with proteins are fields of active research. Small peptides consisting of the 20 natural amino acids typically show high conformational flexibility and a low in‐vivo stability which hampers their application as tools in medicinal diagnostics or molecular biology. One very versatile strategy to overcome such drawbacks is the use of peptidomimetics. These are small molecules which mimic natural peptides or proteins and thus produce the same biological effects as their natural role models. As the field of peptidomimetics is developing fast this review can only provide selected approaches together with examples and is not intended to be comprehensive. We focus on the discussion of amino acid modifications, backbone modifications, global restrictions by cyclisation and on synthetic backbone scaffolds. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Discrimination of cyclic peptide diastereomers by electrospray ionization tandem mass spectrometry
Authors: Zheng Bo , Liu Yiquan , Li Huihui , Ye Yunhua , Gao Xingming , Yuan Gu 
Published: August 2009

AbstractIn this research, the characteristic ions' abundance ratio between two isomers A and B in MS/MS mass spectra was defined as a parameter for discriminating diastereomers. Through this ratio, the discrimination of four pairs of cyclic peptide (CP) diastereomers was successfully achieved. Furthermore, in the analysis of diastereomers' mixtures, both calibration curve and calculational methods were substantiated to have high precision and accuracy. The average absolute errors of the two methods were 2.0 and 2.5% in the 48 measurements of 16 samples, respectively. This research provided a promising approach for the analysis of the CP diastereomers in the fields of asymmetrical synthesis, chiral natural products and structural biology by ESI‐MS/MS. Copyright © 2009 John Wiley & Sons, Ltd.
A note on the Hodges–Lehmann estimator
Authors: Rosenkranz Gerd K. 
Published: August 2009

AbstractThe Hodges‐Lehmann estimator was originally developed as a non‐parametric estimator of a shift parameter. As it is widely used in statistical applications, the question is investigated what it is estimating if the shift model does not hold. It is shown that for data whose distributions are symmetric about their median the Hodges–Lehmann estimator based on the Wilcoxon Rank Sum test estimates the difference between the medians of the distributions. This result does generally not hold if the symmetry assumption is violated. Copyright © 2009 John Wiley & Sons, Ltd.
Investigation of uremic analytes in hemodialysate and their structural elucidation from accurate mass maps generated by a multi‐dimensional liquid chromatography/mass spectrometry approach
Authors: Godfrey A. R. , Williams C. M. , Dudley E. , Newton R. P. , Willshaw P. , Mikhail A. , Bastin L. , Brenton A. G. 
Published: August 2009

AbstractHistorically, structural elucidation of unknown analytes by mass spectrometry alone has involved tandem mass spectrometry experiments using electron ionization. Most target molecules for bioanalysis in the metabolome are unsuitable for detection by this previous methodology. Recent publications have used high‐resolution accurate mass analysis using an LTQ‐Orbitrap with the more modern approach of electrospray ionization to identify new metabolites of known metabolic pathways. We have investigated the use of this methodology to build accurate mass fragmentation maps for the structural elucidation of unknown compounds. This has included the development and validation of a novel multi‐dimensional LC/MS/MS methodology to identify known uremic analytes in a clinical hemodialysate sample. Good inter‐ and intra‐day reproducibility of both chromatographic stages with a high degree of mass accuracy and precision was achieved with the multi‐dimensional liquid chromatography/tandem mass spectrometry (LC/MS/MS) system. Fragmentation maps were generated most successfully using collision‐induced dissociation (CID) as, unlike high‐energy CID (HCD), ions formed by this technique could be fragmented further. Structural elucidation is more challenging for large analytes >270 Da and distinguishing between isomers where their initial fragmentation pattern is insufficiently different. For small molecules (<200 Da), where fragmentation data may be obtained without loss of signal intensity, complete structures can be proposed from just the accurate mass fragmentation data. This methodology has led to the discovery of a selection of known uremic analytes and two completely novel moieties with chemical structural assignments made. Copyright © 2009 John Wiley & Sons, Ltd.
Urinary metabolic profile of phenylketonuria in patients receiving total parenteral nutrition and medication
Authors: Kuhara Tomiko , Ohse Morimasa , Inoue Yoshito , Shinka Toshihiro , Okano Yoshiyuki , Shintaku Haruo , Hongou Kazuhisa , Miyawaki Toshio , Morinobu Wakaba , Tamai Hirosi , Omura Kenji 
Published: August 2009

AbstractNutrition and drugs are main environmental factors that affect metabolism. We performed metabolomics of urine from an 8‐year‐old patient (case 1) with epilepsy and an 11‐year‐old patient (case 2) with malignant lymphoma who was being treated with methotrexate. Both patients were receiving total parenteral nutrition (TPN). We used our diagnostic procedure consisting of urease pretreatment, partial adoption of stable isotope dilution, gas chromatography/mass spectrometry (GC/MS) measurement and target analysis for 200 analytes including organic acids and amino acids. Surprisingly, their metabolic profiles were identical to that of phenylketonuria. The neopterin level was markedly above normal in case 1, and both neopterin and biopterin were significantly above normal in case 2. Mutation analysis of genomic DNA from case 1 showed neither homozygosity nor heterozygosity for phenylalanine hydroxylase deficiency. The metabolic profiles of both cases were normal when they were not receiving TPN. TPN is presently prohibited for individuals who have inherited disorders that affect amino acid metabolism. Although the Phe content of the TPN was not the sole cause of the PKU profile, its effect, combined with other factors, e.g. specific medication or possibly underlying diseases, led to this metabolic abnormality. The present study suggests that GC/MS‐based metabolomics by target analysis could be important for assuring the safety of the treatments for patients receiving both TPN and methotrexate. Metabolomic profiling, both before and during TPN, is useful for determining the optimal nutritional formula not only for neonates, but also for young children who are known heterozygotes for metabolic disorders or whose status is unknown. Copyright © 2009 John Wiley & Sons, Ltd.