bluuebunny/crossref_metadata_2025_split huggingface dataset:
Density functional study of copper‐exchanged zeolites and related microporous materials: Adsorption of nitrosyls
Authors: Uzunova Ellie L. , Mikosch Hans , St. Nikolov Georgi 
Published: March 2012

AbstractDFT periodic, ONIOM, and cluster studies with all‐electron basis sets are applied to Cu(I) exchanged zeolites and silicoalumino‐phosphate analogs with faujasite and chabazite topology. The reactivity of the cations at different cation positions is probed by NO adsorption. In the ONIOM approach, the cation center and the nearest framework environment are described by DFT, whereas a larger part of the structure is modeled at the semiempirical PM6 level. The importance of including all electrons explicitly in the periodic model computations is outlined by comparison of the results with those from ONIOM and previous plane‐wave studies. The Cu(I) cations reside at distinct extraframework cation sites in the vicinity of the double six‐membered rings (D6R) and upon adsorption they experience a displacement from their previous position. A full optimization with all‐electron basis set is a prerequisite for proper elucidation of the coordination of the transition metal cations by the framework oxygen atoms. © 2012 Wiley Periodicals, Inc.
Correlation measures as benchmarks in reduced density matrix functional theory
Authors: Lathiotakis N. N. 
Published: March 2012

AbstractIn reduced density matrix functional theory, approximate total energy expressions in terms of the one‐body reduced density matrix (1RDM) are minimized under the appropriate N‐representability subsidiary conditions. The optimal 1RDM is in general nonidempotent. Measures of nonidempotency are the total charge of weakly occupied states and correlation entropy given in terms of the eigenvalues of the 1RDM. In this work, we calculate these quantities for several systems using different 1RDM functionals and compare with accurate results from a multideterminant method. Our goal is to assess 1RDM functionals with respect to the quality of the obtained 1RDM. © 2012 Wiley Periodicals, Inc.
Robotic transaxillary thyroidectomy with gasless approach in a girl with goitre
Authors: Kandil Emad , Noureldine Salem , Abdel Khalek Mohamed , Aslam Rizwan , Ekaidi Ibrahim , Steiner Rodney , Holsinger Floyd C. 
Published: March 2012

AbstractBackgroundRobotic‐assisted transaxillary thyroidectomy is a minimally invasive approach for the removal of the thyroid through the axilla. This technique eliminates a visible scar and affords excellent optics of the cervical anatomy. We sought to describe the technique and outcome for transaxillary gasless subtotal thyroidectomy in the paediatric population.MethodsA 13 year‐old female with an enlarged goitre underwent a transaxillary robot‐assisted gasless subtotal thyroidectomy in an academic institution. The main outcome measures were feasibility of the robotic approach, patient and gland characteristics, operative time and complications.ResultsThere was no conversion to laparoscopic or open surgery. The robotic docking time was 110 min and total operative time was 150 min. The patient tolerated the procedure well. Estimated blood loss was 10 ml. The patient was discharged within 24 h. There were no perioperative or postoperative complications. In addition there was no evidence of postoperative vocal cord palsy or paresis.ConclusionsThis initial experience demonstrates that this technique can be a feasible, safe and effective method for subtotal thyroidectomy in the paediatric population. The use of robotic technology for endoscopic thyroid surgery could overcome the limitations of conventional endoscopic surgeries in the surgical management of thyroid disease. Copyright © 2012 John Wiley & Sons, Ltd.
Gold Nanoparticles Supported on Nanoparticulate Ceria as a Powerful Agent against Intracellular Oxidative Stress
Authors: Menchón Cristina , Martín Roberto , Apostolova Nadezda , Victor Victor M. , Álvaro Mercedes , Herance José Raúl , García Hermenegildo 
Published: March 2012

AbstractCeria‐supported gold nanoparticles are prepared exhibiting peroxidase activity and acting as radical traps. Au/CeO2 shows a remarkable biocompatibility as demonstrated by measuring cellular viability, proliferation, and lack of apoptosis for two human cell lines (Hep3B and HeLa). The antioxidant activity of Au/CeO2 against reactive oxygen species (ROS) is demonstrated by studying the cellular behavior of Hep3B and HeLa in a model of cellular oxidative stress. It is determined that Au/CeO2 exhibits higher antioxidant activity than glutathione, the main cytosolic antioxidant compound, and its CeO2 carrier. Overall the result presented here shows the potential of implementing well‐established nanoparticulated gold catalysts with remarkable biocompatibility in cellular biology.
Cloned code: stable code
Authors: Harder Jan , Göde Nils 
Published: March 2012

SUMMARYCode clones are said to threaten the maintainability of a system—especially when the system evolves and source code is changed. Whether clones increase maintenance effort can be analyzed by comparing the stability of cloned code with the stability of non‐cloned code. A previous study found that cloned code is even more stable than non‐cloned code and, thus, may require less maintenance effort—contrary to the frequently voiced assumption. In this paper, we partially replicate this study using a more fine‐grained measurement. We furthermore extend the study to subject systems from academia and industry and evaluate the effect of different clone detection parameters on clone stability and how the stability changes over time. In general, we were able to confirm the findings of the previous study. Nevertheless, our results also show that clone stability varies depending on the clones' characteristics, the corresponding project environment, and over time. Copyright © 2012 John Wiley & Sons, Ltd.
Genetically modified pigs for biomedical research
Authors: Luo Yonglun , Lin Lin , Bolund Lars , Jensen Thomas G. , Sørensen Charlotte Brandt 
Published: March 2012

AbstractDuring the last two decades, pigs have been used to develop some of the most important large animal models for biomedical research. Advances in pig genome research, genetic modification (GM) of primary pig cells and pig cloning by nuclear transfer, have facilitated the generation of GM pigs for xenotransplantation and various human diseases. This review summarizes the key technologies used for generating GM pigs, including pronuclear microinjection, sperm‐mediated gene transfer, somatic cell nuclear transfer by traditional cloning, and somatic cell nuclear transfer by handmade cloning. Broadly used genetic engineering tools for porcine cells are also discussed. We also summarize the GM pig models that have been generated for xenotransplantation and human disease processes, including neurodegenerative diseases, cardiovascular diseases, eye diseases, bone diseases, cancers and epidermal skin diseases, diabetes mellitus, cystic fibrosis, and inherited metabolic diseases. Thus, this review provides an overview of the progress in GM pig research over the last two decades and perspectives for future development.
Seed dormancy and germination in the giant Himalayan lily (Cardiocrinum giganteum var. giganteum): an assessment of its potential for naturalization in northern Japan
Authors: Phartyal Shyam S. , Kondo Tetsuya , Baskin Carol C. , Baskin Jerry M. 
Published: March 2012

AbstractUnderstanding the potential for ornamental plant species to become naturalized in a nonnative habitat requires information on seed germination in order to help predict responses of the species to the natural environmental conditions of its new habitat. Cardiocrinum giganteum var. giganteum, which is native to the Himalayas, has been introduced as an ornamental plant in temperate regions of the world, and was categorized recently as invasive in New Zealand. Seed germination requirements of the species were determined under natural conditions in Hokkaido, Japan, to assess its potential to become naturalized in this region of Japan. Mature seeds were collected from its native range in the Indian Himalayas. At maturity in autumn, seeds had underdeveloped embryos, which grew in the second autumn and winter after exposure to summer temperatures. Radicles and cotyledons emerged in late winter and spring. Thus, an 18–19 month period was required from dispersal to seed germination. Under laboratory conditions, this period could be shortened to 10–11 months in a 25/15 °C (120 days) → 15/5 °C (90 days) → 0 °C (90 days) → 15/5 °C (60 days) temperature sequence. GA3 did not substitute for the above temperature requirements. These temperature requirements for seed germination of C. giganteum var. giganteum are very similar to those of its native Japanese congener C. cordatum var. glehnii. Seeds of both taxa have deep simple morphophysiological dormancy. The close similarity in the requirements for regeneration from seeds of the two taxa suggests that the seed stage of the life cycle is not an impediment to the naturalization of the giant Himalayan lily in northern Japan.
School connectedness, peer attachment, and self‐esteem as predictors of adolescent depression
Authors: Millings Abigail , Buck Rhiannon , Montgomery Alan , Spears Melissa , Stallard Paul 
Published: March 2012

ABSTRACTRecent literature suggests that school connectedness (SC) may be a key determinant of adolescent mental health. Specifically, SC has been found to have a negative relationship with adolescent depression. In the current, cross sectional study, we examine whether the relationship between SC and symptoms of low mood is dampened or moderated by self‐esteem (SE) and peer attachment style. Participants were 5022 adolescents (aged 11–16) who completed a battery of questionnaires in school, including measures of low mood, SC, SE, and peer attachment style. The relationship between SC and low mood was reduced by the inclusion of SE and peer attachment style. Peer attachment style was the largest predictor of low mood. The relationship between SC and low mood was not moderated by SE or peer attachment style. Interventions for adolescent depression may be most effective by focussing on increasing SE and fostering secure attachments, rather than solely focussing on increasing SC.
PARTICIPATORY IMPACT ASSESSMENT OF RICE PARBOILING VIDEOS WITH WOMEN IN BENIN
Authors: ZOSSOU ESPÉRANCE , VAN MELE PAUL , WANVOEKE JONAS , LEBAILLY PHILIPPE 
Published: March 2012

SUMMARYUsing the sustainable livelihoods framework to evaluate the impact of a farmer-to-farmer video on the improved rice parboiling technology, women in Benin rated financial, social, human, natural and physical capital stocks for the baseline year (2006) and the impact year (2009) on a 0–5 scale. Women who had watched the video and those who had not, but who lived in the same villages, perceived a significant improvement in four out of five livelihood capitals while processors in control villages did not perceive any significant change. Apart from testing the sustainable livelihoods conceptual framework as a participatory impact assessment tool for video-mediated rural learning, this study shows how farmer-to-farmer training videos helped to improve multiple livelihood assets.
The only known cyclopygid–‘atheloptic’ trilobite fauna from North America: the upper Ordovician fauna of the Pyle Mountain Argillite and its palaeoenvironmental significance
Authors: OWEN ALAN W. , BRUTON DAVID L. 
Published: March 2012

AbstractThe trilobite fauna of the upper Ordovician (middle Katian) Pyle Mountain Argillite comprises a mixture of abundant mesopelagic cyclopygids and other pelagic taxa and a benthic fauna dominated by trilobites lacking eyes. Such faunas were widespread in deep water environments around Gondwana and terranes derived from that continent throughout Ordovician time but this is the only known record of such a fauna from North America and thus from Laurentia. It probably reflects a major sea level rise (the ‘Linearis drowning events’) as does the development of coeval cyclopygid-dominated deep water trilobite faunas in terranes that were marginal to Laurentia and are now preserved in Ireland and Scotland. The Pyle Mountain Argillite trilobite fauna occurs with a deep waterFoliomenabrachiopod fauna and comprises 22 species. Pelagic trilobites (mostly cyclopygids) constitute 36% of the preserved sclerites, and 45% of the fauna is the remains of trilobites lacking eyes, including one new species,Dindymene whittingtonisp. nov. Three species of cyclopygid are present, belonging inCyclopyge,SymphysopsandMicroparia(Heterocyclopyge). Cyclopygids are widely thought to have been stratified in the water column in life and thus their taxonomic diversity reflects the relative depths of the sea-beds on which their remains accumulated. A tabulation of middle and upper Katian cyclopygid-bearing faunas from several palaeoplates and terranes arranged on the basis of increasing numbers of cyclopygid genera allows an assessment of the relative depth ranges of the associated benthic taxa. The Pyle Mountain Argillite fauna lies towards the deeper end of this depth spectrum.
Age at onset of non-affective psychosis in relation to cannabis use, other drug use and gender
Authors: Dekker N. , Meijer J. , Koeter M. , van den Brink W. , van Beveren N. ,   GROUP Investigators:, Kahn R. S. , Linszen D. H. , van Os J. , Wiersma D. , Bruggeman R. , Cahn W. , de Haan L. , Krabbendam L. , Myin-Germeys I. 
Published: March 2012

BackgroundCannabis use is associated with an earlier age at onset of psychotic illness. The aim of the present study was to examine whether this association is confounded by gender or other substance use in a large cohort of patients with a non-affective psychotic disorder.MethodIn 785 patients with a non-affective psychotic disorder, regression analysis was used to investigate the independent effects of gender, cannabis use and other drug use on age at onset of first psychosis.ResultsAge at onset was 1.8 years earlier in cannabis users compared to non-users, controlling for gender and other possible confounders. Use of other drugs did not have an additional effect on age at onset when cannabis use was taken into account. In 63.5% of cannabis-using patients, age at most intense cannabis use preceded the age at onset of first psychosis. In males, the mean age at onset was 1.3 years lower than in females, controlling for cannabis use and other confounders.ConclusionsCannabis use and gender are independently associated with an earlier onset of psychotic illness. Our findings also suggest that cannabis use may precipitate psychosis. More research is needed to clarify the neurobiological factors that make people vulnerable to this precipitating effect of cannabis.
The Humanity of Christ: John Calvin's Understanding of Christ's Vicarious Humanity
Authors: Ahn Ho-Jin 
Published: March 2012

AbstractThere are two different hermeneutical principles between the views of the fallen and unfallen humanity of Christ. Scholars who deny Christ's assumption of corrupted human nature emphasise that, due to a fallen humanity, Christ would have inevitably committed sin in the context of the original sin. However, theologians who are in favour of Christ's fallen humanity explain the issue in the person and work of Christ himself. Here, I present John Calvin's biblical views on the body of Christ as the vicarious humanity for all of us. With regard to the biblical truth that the Word became flesh without ceasing to be the eternal of God, Calvin describes the paradoxical character of the event in scripture. Although Calvin never supports the fallen nature of Christ at a literal level, he is inclined to accept the view of Christ's fallen nature at the level of interpretation, because Calvin has no hesitation in saying that Christ assumed a mortal body like us. Calvin is in line with the views of Christ's fallen human nature, for he uses the biblical concept of Christ's mortal body and the principle of sanctification in his own body through the Holy Spirit, except in that Calvin denies Christ's assumption of the sinful nature of Adam after the Fall. Calvin's opinions not only provide us with the common biblical ground with which the two theological camps would agree, but also demonstrate that Christ assumed fallen humanity for us. In this article, I will explain how the view of Christ's unfallen humanity has logical errors and how it distorts the integrity of the Gospel. Next, in order to demonstrate how Christ's assumption of fallen humanity accords with the orthodox faith in Reformed theology, I examine Calvin's biblical arguments of Christ's assumption of our true humanity. Then, I explain that without assumption of our mortal body by Christ there is no vicarious humanity of Christ in Calvin's christology. Particularly, in order to understand the original and biblical arguments for the humanity of Christ, I will use a dialectical approach to both the Institutes of Christian Religion (1559) and Calvin's commentaries, as the best way to grasp the essence of Calvin's theology.
An Accommodating and Shunning Culture: Evaluating the Cultural Context of the Evangelical Theological Society in the United States
Authors: White C. Jason 
Published: March 2012

AbstractIn the first decade of the twenty-first century, the Evangelical Theological Society (ETS) in the United States (US) went through a shift because of the introduction of open theism into theological context of conservative evangelicalism. The response by the society to this new theology was swift and decisive. Not only were the memberships of certain evangelicals (i.e. Clark H. Pinnock and John Sanders), who were responsible for bringing open theism into the ETS, in danger of being revoked, but the ETS formally denounced open theism and changed its constitutional by-laws to safeguard itself against anyone bringing significant theological innovation into the society. It is important to re-examine the cultural ethos of the ETS in the US in terms of the underlying beliefs of the society in order to determine whether or not the changes the ETS made had basis in scripture or were simply motivated by the culture at large. To determine this, this article will begin by generally describing some of the main cultural beliefs of the ETS. Next, the discussion focuses on some of the major historical influences of the nineteenth and twentieth centuries, which impacted the ETS to conform to an ethos more in line with the Enlightenment. Third, the article will critique these Enlightenment-based cultural beliefs linguistically, culturally and theologically. This article will demonstrate that because the ETS conformed more to the standards of the Enlightenment than to scripture, it is generally much more preoccupied with knowing the truth of scripture rather than walking in the way of Jesus Christ. Finally, this article suggests the way forward for the ETS is to become a more inclusive society by aligning itself with a more historical definition of evangelicalism rather than simply being defined by the evangelicalism of the late nineteenth and twentieth centuries. This article suggests that by making this move, the ETS will reclaim a much more grace-filled attitude towards its current members and give hope to those committed Christ-followers on the outside of the society, showing them they are welcome to be a part of such a prestigious theological group.
Further Work at Llanfor Roman Military Complex
Authors: Hopewell David , Hodgson Nick 
Published: March 2012

AbstractGeophysical survey at Llanfor, near Bala, revealed two temporary camps and a large wooden fort in exceptional detail. The camps are assumed to be evidence of an early Flavian invasion force. The fort, which contained a garrison that probably comprised a complete ala of auxiliary cavalry and a cohort of legionaries, is interpreted as a short-lived campaign base that existed during the transition between invasion and consolidated occupation. Parallels are drawn between Llanfor and similar forts in Britain and Germany.
Quantitative EEG Spectrum-weighted Frequency (Brain Rate) Distribution in Adults with ADHD
Authors: Markovska-Simoska Silvana , Pop-Jordanova Nada 
Published: March 2012

AbstractObjectiveThe aim of this study is to explore the applicability of brain rate (fb) for the diagnosis of attention-deficit/hyperactivity disorder (ADHD), analyzing the spatial distribution of fb through analysis of its values in sagittal and lateral electrodes' positions, recorded in four conditions (eyes closed, eyes opened, visual continuous performance task and emotional continuous performance task).MethodsSixty-seven adults diagnosed with ADHD according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and 50 age-matched control subjects participated in the study. The brain activity of the subjects was recorded by 19 channel quantitative electroencephalography (QEEG) system and fb was calculated with the fb software.ResultsMaximum values of fb for sagittal topography are obtained in central region and the minimum in frontal region, while lateral topography maximum values are found in the left and right sides and the minimum in midline region. A positive correlation between the fb values and the QEEG spectra subtypes was obtained, with lower values for normals, first and second subtype, and higher values for the third and fourth subtype. On the other hand, there was no correlation between behavioral symptoms and fb values.ConclusionThe applicability of an fb indicator in the diagnosis of ADHD is especially pronounced for the higher subtypes (ADHD III and IV), corresponding to heterogeneous and multifactorial character of this disorder.
Marked Response to VNS in a Post-Cingulotomy Patient: Implications for the Mechanism of Action of VNS in TRD
Authors: Conway Charles R. , Gebretsadik Mehret D. , Bucholz Richard D. 
Published: March 2012

AbstractTreatment-resistant major depression (TRMD, major depressive disorder that fails to respond to numerous therapies) is a relatively common and clinically challenging disorder. In many cases, the most severely affected TRMD patients have received surgical intervention (subcaudate tractotomy, limbic leucotomy, anterior capsulotomy, and anterior cingulotomy). New treatments, including vagus nerve stimulation (VNS) and deep brain stimulation, have emerged to treat individuals with TRMD. We describe the case of a woman, 53 years of age, with a long and sustained history of TRMD (33 years), which was unresponsive to numerous treatments (multiple pharmacotherapies, psychotherapy, electroconvulsive therapy [ECT]). Additionally, her TRMD failed to respond to a bilateral anterior cingulotomy. She underwent placement of a cervical vagus nerve stimulator and a brief course of ECT (3 unilateral treatments). Her depression improved markedly, and it has remained in sustained remission for 3.5 years. This case suggests a potential synergistic effect of VNS and ECT, as well as provides possible clues to the neural circuitry of VNS in TRMD.