bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lateral Tibial Plateau Fracture Depression as a Predictor of Lateral Meniscus Pathology
Authors: Ringus Vytautas M. , Lemley Frederick R. , Hubbard David F. , Wearden Stanley , Jones Dina L. 
Published: March 2010

The goal of this study was to determine if the degree of lateral tibial plateau fracture depression on computed tomography (CT) images predicted the presence of lateral meniscus tears. The study group comprised 85 patients who sustained a lateral tibial plateau fracture and underwent open reduction and internal fixation by the same surgeon. Degree of plateau depression was measured in millimeters by CT. Operative reports were retrospectively reviewed to determine if the lateral meniscus tear was intact or torn at the time of surgery. Twenty-eight patients had a lateral meniscus tear noted at the time of surgery. No significant differences existed in gender, mechanism or energy level of injury, Schatzker classification, or type of fracture among patients with a lateral meniscal tear as compared to those without a tear. Patients with ⩾10 mm of plateau depression had an eight-fold increase in risk of having a lateral meniscus tear compared to those with <10 mm of depression. Patients younger than 48 years had a four-fold increase in risk of having a lateral meniscus tear than older patients.
This study demonstrated an association between the amount of tibial plateau depression and the likelihood of a lateral meniscus tear. These findings may be used to predict those who have sustained a tear of the lateral meniscus and to advise the surgeon to prepare for a repair. Further prospective studies using magnetic resonance imaging as a tool to evaluate the extent of soft tissue injuries in plateau fractures is needed.
A Comparative Study of Screw and Helical Proximal Femoral Nails for the Treatment of Intertrochanteric Fractures
Authors: Park Jung Ho , Lee Yong Seuk , Park Jong Woong , Wang Joon Ho , Kim Jae Gyoon 
Published: March 2010

The goal of this study was to compare treatment outcomes of screw proximal femoral nails and helical proximal femoral nails and to investigate the effectiveness of helical proximal femoral nails for the treatment of intertrochanteric fractures. Forty patients with intertrochanteric fractures were treated at our institution between January 2005 and January 2007, with a minimum follow-up of 1.5 years. Seventeen patients were treated with screw proximal femoral nails (mean patient age, 67 years; age range, 45–89 years; men:women ratio, 3:14), and 23 were treated with helical proximal femoral nails (mean patient age, 74 years; age range, 64–91 years; men:women ratio, 6:17). We evaluated mean operation time, amount of bleeding, time to ambulation, average union period, changes in neck shaft angle, and complications, and performed radiographic reviews, telephone interviews, and direct contact interviews at an outpatient clinic. We evaluated postoperative function and mobility using social function scores and mobility scores.
Helical proximal femoral nails produced better results in terms of social function scores, mobility scores, and complication rates with statistical significance. No significant differences were found between the 2 nails in terms of mean operation time, amount of bleeding, average union period, time to ambulation, or neck shaft angle changes. Screw proximal femoral nails and helical proximal femoral nails are suitable implants for intertrochanteric fractures, but helical proximal femoral nails are better in terms of functional aspects and complication rates.
The Use of Expandable Cages in Patients Undergoing Multilevel Corpectomies for Metastatic Tumors in the Cervical Spine
Authors: Omeis Ibrahim , Bekelis Kimon , Gregory Anthony , McGirt Matthew , Sciubba Daniel , Bydon Ali , Wolinsky J.P. , Gokaslan Ziya , Witham Timothy 
Published: March 2010

Expandable cages have been used successfully to reconstruct the anterior spinal column in the treatment of traumatic, neoplastic, infectious, and degenerative spine disease. To the best of our knowledge, no studies report the results of the use of expandable cages in patients undergoing multilevel corpectomies for cervical spine metastatic disease. We report our experience with the use of expandable cages in this subgroup of patients.
From August 2006 to May 2008, 5 patients presenting with myelopathy, pain, and/or radiculopathy secondary to metastatic disease of the cervical spine underwent multilevel cervical corpectomies and placement of expandable cages in our institution. All procedures were supplemented with an anterior cervical plate and with posterior instrumentation to achieve a 360° fusion. A visual analog scale (VAS), Nurick grade, Frankel grade, American Spinal Injuries Association (ASIA) grade, and Ranawat grade were used to evaluate patients pre- and postoperatively. The mean follow-up period was 13.2 months. Three patients underwent a 2-level corpectomy, 1 a 3-level corpectomy, and 1 a 4-level corpectomy. Postoperative imaging studies showed that all patients had correction of preoperative kyphosis. The mean VAS score was reduced from 6.4 to 1. All other indices of spinal cord injury measured improved postoperatively or were stabilized. Postoperative imaging studies showed stable constructs in 4 patients.
The use of expandable cages in multilevel corpectomies for the treatment of metastatic cervical spine disease appears to be a safe and effective way to reconstruct the anterior column of the cervical spine, preventing further neurologic deterioration.
Assessment of Family Needs in Neonatal Intensive Care Units
Authors: Mundy Cynthia A. 
Published: March 2010

Background Limited research has been conducted to assess family needs in neonatal intensive care units. Health care providers often make assumptions about what families need, but these assumptions are unfounded and can lead to inappropriate conclusions. When assessed appropriately, family needs can be incorporated into individualized plans of care, enhancing family-centered care.
Objective To assess the needs of parents in neonatal intensive care units, we asked the following 3 questions: What are the most and least important needs of families in a level III neonatal intensive care unit? Do parents’ needs differ at admission and discharge? Do the needs of mothers and fathers differ?
Methods Parents were interviewed by using the Neonatal Intensive Care Unit Family Needs Inventory. Participants rated statements as not important (1), slightly important (2), important (3), very important (4), or not applicable (5).
Results Fifty-two (93%) of the 56 items were rated as important or very important, and parents rated assurance-type needs highest. Parents at admission rated support needs higher than parents at discharge rated those needs. Needs of mothers and fathers did not differ significantly.
Conclusions Identifying the needs of parents in neonatal intensive care units can enhance nursing communication and allow nurses to incorporate parents’ needs into families’ plans of care. The family needs inventory can help identify those needs and allows the integration of individualized nursing care to fulfill those needs, providing a positive family-centered experience in the unit for patients and their families.
Impact of Morbidity and Mortality Conferences on Analysis of Mortality and Critical Events in Intensive Care Practice
Authors: Ksouri Hatem , Balanant Per-Yann , Tadié Jean-Marc , Heraud Guillaume , Abboud Imad , Lerolle Nicolas , Novara Ana , Fagon Jean-Yves , Faisy Christophe 
Published: March 2010

Background Morbidity and mortality conferences are a tool for evaluating care management, but they lack a precise format for practice in intensive care units.
Objectives To evaluate the feasibility and usefulness of regular morbidity and mortality conferences specific to intensive care units for improving quality of care and patient safety.
Methods For 1 year, a prospective study was conducted in an 18-bed intensive care unit. Events analyzed included deaths in the unit and 4 adverse events (unexpected cardiac arrest, unplanned extubation, reintubation within 24–48 hours after planned extubation, and readmission to the unit within 48 hours after discharge) considered potentially preventable in optimal intensive care practice. During conferences, events were collectively analyzed with the help of an external auditor to determine their severity, causality, and preventability.
Results During the study period, 260 deaths and 100 adverse events involving 300 patients were analyzed. The adverse events rate was 16.6 per 1000 patient-days. Adverse events occurred more often between noon and 4 pm (P = .001).The conference consensus was that 6.1% of deaths and 36% of adverse events were preventable. Preventable deaths were associated with iatrogenesis (P = .008), human errors (P &lt; .001), and failure of unit management factors or communication (P = .003). Three major recommendations were made concerning standardization of care or prescription and organizational management, and no similar incidents have recurred.
Conclusion In addition to their educational value, regular morbidity and mortality conferences formatted for intensive care units are useful for assessing quality of care and patient safety.
Oral Care Practices for Orally Intubated Critically Ill Adults
Authors: Feider Laura L. , Mitchell Pamela , Bridges Elizabeth 
Published: March 2010

Background Ventilator-associated pneumonia is a major threat to patients receiving mechanical ventilation in hospitals. Oral care is a nursing intervention that may help prevent ventilator-associated pneumonia.Objectives To describe oral care practices performed by critical care nurses for orally intubated critically ill patients and compare these practices with recommendations for oral care in the 2005 AACN Procedure Manual for Critical Care and the guidelines from the Centers for Disease Control and Prevention.Methods A descriptive, cross-sectional design with a 31-item Web-based survey was used to describe oral care practices reported by 347 randomly selected members of the American Association of Critical-Care Nurses.Results Oral care was performed every 2 (50%) or 4 (42%) hours, usually with foam swabs (97%). Oral care was reported as a high priority (47%). Nurses with 7 years or more of critical care experience performed oral care more often (P=.008) than did less experienced nurses. Nurses with a bachelor’s degree in nursing used foam swabs (P=.001), suctioned the mouth before the endotracheal tube (P=.02), and suctioned after oral care (P&lt;.001) more often than other nurses. Nurses whose units had an oral care policy (72%) reported that the policy indicated using a toothbrush (63%), using toothpaste (40%), brushing with a foam swab (90%), using chlorhexidine gluconate oral rinse (49%), suctioning the oral cavity (84%), and assessing the oral cavity (73%). Oral care practices and policies differed for all those items.Conclusions Survey results indicate that discrepancies exist between reported practices and policies. Oral care policies appear to be present, but not well used.
Clinicians’ Perception of Head-of-Bed Elevation
Authors: Hiner Chad , Kasuya Tomoyo , Cottingham Christine , Whitney JoAnne 
Published: March 2010

Background Head-of-bed elevation of 30° to 45° is important in preventing ventilator-associated pneumonia, but clinicians’ perception and determination of head-of-bed elevation are not widely reported.Objectives To (1) document the accuracy of clinicians’ perception of head-of-bed elevation, (2) document methods clinicians use to determine the head-of-bed angle, and (3) assess knowledge of recommended head-of-bed elevation.Methods Clinicians (n = 175) viewed a simulated patient with head of bed elevated 30° and elevation gauge concealed. They answered 3 questions: What is the level of the head of the bed? What head-of-bed elevation is associated with decreased incidence of ventilator-associated pneumonia? When providing care, how do you routinely determine the head-of-bed elevation?Results Fifty percent of 89 registered nurses and 53% of 39 physicians identified head-of-bed elevation correctly (±5°). Head-of-bed elevation was perceived accurately by 86% of 21 respiratory therapists, 63% of 16 medical assistants, and 50% of 10 physical/occupational therapists. Ninety-five percent of nurses and respiratory therapists, 79% of physicians, 90% of physical/occupational therapists, and 46% of medical assistants correctly identified the head-of-bed angle associated with decreases in occurrence of ventilator-associated pneumonia. Techniques for determining the angle varied; 58% of respondents reported using the gauge.Conclusions Head-of-bed angle was perceived correctly by 50% to 86% of clinicians. Nurses tended to underestimate the angle, whereas other clinicians tended to overestimate. Nurses, respiratory therapists, and physical/occupational therapists showed the best understanding of the correct angle for minimizing occurrence of ventilator-associated pneumonia. Elevation gauges were most often used to determine the angle.
Superconducting Nanowires Fabricated Using Molecular Templates
Authors: Bezryadin Alexey , Goldbart Paul M. 
Published: March 2010

AbstractThe application of single molecules as templates for nanodevices is a promising direction for nanotechnology. We use suspended deoxyribonucleic acid molecules or single‐walled carbon nanotubes as templates for fabricating superconducting devices and then study these devices at cryogenic temperatures. Because the resulting nanowires are extremely thin, comparable in diameter to the templating molecule itself, their electronic state is highly susceptible to thermal fluctuations. The most important family of these fluctuations are the collective ones, which take the form of Little's phase slips or ruptures of the many‐electron organization. These phase slips break the quantum coherence of the superconducting condensate and render the wire slightly resistive (i.e., not fully superconducting), even at temperatures substantially lower than the critical temperature of the superconducting transition. At low temperatures, for which the thermal fluctuations are weak, we observe the effects of quantum fluctuations, which lead to the phenomenon of macroscopic quantum tunneling. The modern fabrication method of molecular templating, reviewed here, can be readily implemented to synthesize nanowires from other materials, such as normal metals, ferromagnetic alloys, and semiconductors.
Modeling phase equilibria for acid gas mixtures using the CPA equation of state. I. Mixtures with H2S
Authors: Tsivintzelis Ioannis , Kontogeorgis Georgios M. , Michelsen Michael L. , Stenby Erling H. 
Published: March 2010

AbstractThe Cubic‐Plus‐Association (CPA) equation of state is applied to a large variety of mixtures containing H2S, which are of interest in the oil and gas industry. Binary H2S mixtures with alkanes, CO2, water, methanol, and glycols are first considered. The interactions of H2S with polar compounds (water, methanol, and glycols) are modeled assuming presence or not of cross‐association interactions. Such interactions are accounted for using either a combining rule or a cross‐solvation energy obtained from spectroscopic data. Using the parameters obtained from the binary systems, one ternary and three quaternary mixtures are considered. It is shown that overall excellent correlation for binary mixtures and satisfactory prediction results for multicomponent systems are obtained. There are significant differences between the various modeling approaches and the best results are obtained when cross association is explicitly accounted for, especially using the cross‐association energy from independent experimental studies rather than from combining rules. © 2010 American Institute of Chemical Engineers AIChE J, 2010
Progress toward a biomimetic leaf: 4,000 h of hydrogen production by coating‐stabilized nongrowing photosynthetic Rhodopseudomonas palustris
Authors: Gosse Jimmy L. , Engel Brian J. , Hui Jeremy C.‐H. , Harwood Caroline S. , Flickinger Michael C. 
Published: March 2010

AbstractIntact cells are the most stable form of nature's photosynthetic machinery. Coating‐immobilized microbes have the potential to revolutionize the design of photoabsorbers for conversion of sunlight into fuels. Multi‐layer adhesive polymer coatings could spatially combine photoreactive bacteria and algae (complementary biological irradiance spectra) creating high surface area, thin, flexible structures optimized for light trapping, and production of hydrogen (H2) from water, lignin, pollutants, or waste organics. We report a model coating system which produced 2.08 ± 0.01 mmol H2 m−2 h−1 for 4,000 h with nongrowing Rhodopseudomonas palustris, a purple nonsulfur photosynthetic bacterium. This adhesive, flexible, nanoporous Rps. palustris latex coating produced 8.24 ± 0.03 mol H2 m−2 in an argon atmosphere when supplied with acetate and light. A simple low‐pressure hydrogen production and trapping system was tested using a 100 cm2 coating. Rps. palustris CGA009 was combined in a bilayer coating with a carotenoid‐less mutant of Rps. palustris (CrtI−) deficient in peripheral light harvesting (LH2) function. Cryogenic field emission gun scanning electron microscopy (cryo‐FEG‐SEM) and high‐pressure freezing were used to visualize the microstructure of hydrated coatings. A light interaction and reactivity model was evaluated to predict optimal coating thickness for light absorption using the Kubelka‐Munk theory (KMT) of reflectance and absorptance. A two‐flux model predicted light saturation thickness with good agreement to observed H2 evolution rate. A combined materials and modeling approach could be used for guiding cellular engineering of light trapping and reactivity to enhance overall photosynthetic efficiency per meter square of sunlight incident on photocatalysts. © 2010 American Institute of Chemical Engineers Biotechnol. Prog., 2010
Application of the yeast‐surface‐display system for orally administered salmon calcitonin and safety assessment
Authors: Sun Ping‐Nan , Zhang Xue‐Cheng , Chen Yun‐Song , Zang Xiao‐Nan 
Published: March 2010

AbstractHigh manufacturing costs and oral delivery are the constraints in clinical application of calcitonin. We selected surface‐displayed Saccharomyces cerevisiae as a low‐cost and safe carrier for oral delivery of salmon calcitonin (sCT). The sCT DNA fragment, optimized according to the codon preference of S. cerevisiae, was synthesized and cloned into the plasmid M‐pYD1 to yield recombinant yAGA2‐sCT, which was induced to express sCT by galactose for 0, 12, and 24 h. sCT expression was detected on the cell surface by indirect immunofluorescence and peaked at 12 h. About 65% recombinants expressed sCT on flow cytometry. The in vivo and in vitro activity of recombinant sCT was determined by detecting bioactivity of antiosteoclastic absorption on bone wafers and orally administering yAGA2‐sCT to Wistar rats, respectively. For safety assessment of yAGA2‐sCT, we observed abnormalities, morbidity, and mortality and determined body weight, serum chemistry parameters, hematological parameters, and organ weight. In vitro bioactivity of the recombinant sCT was similar to that of commercial sCT, Miacalcic; oral administration of 5 g/kg yAGA2‐sCT induced a long‐term hypocalcemic effect in Wistar rats and no adverse effects. This study demonstrates that yAGA2‐sCT anchoring sCT protein on a S. cerevisiae surface has potential for low‐cost and safe oral delivery of sCT. © 2010 American Institute of Chemical Engineers Biotechnol. Prog., 2010
Blood supply to the lymphatic vessels in the leg: An incidental finding
Authors: Pan Wei‐Ren , le Roux Cara Michelle 
Published: March 2010

AbstractThere are no reports or images of the blood supply to the lymphatic vessels. One lower limb of an unembalmed human cadaver was studied. Hydrogen peroxide (6%) was applied to find the lymphatic vessels by using a surgical microscope. The vessels were injected with a radio‐opaque mixture and dissected. During the dissection, several sites of paralymphatics arteriole nutrient (PAN) vessels were found in close proximity to collecting lymphatic vessels in the medial aspect of the leg. The caliber of the lymphatic vessels was about 1 mm. The caliber of PAN vessels was <0.1 mm. The blood vessels were seen running along the lymphatic vessels. Some of them crossing the lymphatics and supplying the fatty tissue nearby and some running parallel on the lymph vessel walls. Histology sections show different‐sized PAN vessels containing blood cells situated close to the lymphatic wall and within the lymphatic vessel wall. PAN vessels have been found and described. It will upgrade our anatomical knowledge and also be of benefit for medical and/or scientific research. Clin. Anat. 23:451–454, 2010. © 2010 Wiley‐Liss, Inc.
Evaluation of anatomical variation of the crista galli using computed tomography
Authors: Hajiioannou Jiannis , Owens David , Whittet Heikki B. 
Published: March 2010

AbstractPneumatization of the crista galli is a recognized incidental finding on computed tomography (CT), usually with little relevance to the clinical picture. There are, however, notable exceptions: congenital midline nasal defects including nasal dermoids have been seen to track through or near the crista galli. Mucocele development has also been seen. This study aimed to evaluate the variation in crista galli morphology and pneumatization and assess whether specific morphologies occur. A retrospective observational study was undertaken between November 2007 and January 2008. Using coronal and axial reconstructed CT views, images of the head in the region of the paranasal sinuses were assessed. Variations in the crista galli were classified according to their position relative to the cribriform plate and to the degree of pneumatization. Computed tomography findings of the morphology of the crista galli in 99 patients were reviewed and a classification system derived from the findings. Three variations of the position of the base of the crista galli were defined. In 28.3% of subjects the base of the crista galli did not extend below the level of the cribriform plate. In 63.6%, the crista galli extended less than 50% of its height below the cribriform plate and in 8.1% of the scans the crista galli extended more than 50% of its height below the cribriform plate. Pneumatization was noticed in 14.1% of the scans. Our results demonstrate the variation that occurs in the morphology and pneumatization of the crista galli. We hope this knowledge might be of help in preoperative planning of surgical approaches to sites of disease involving the crista galli. Clin. Anat. 23:370–373, 2010. © 2010 Wiley‐Liss, Inc.
Percutaneous coronary intervention with a virtual 2‐Fr system
Authors: Tanaka Akihito , Saito Shigeru 
Published: March 2010

AbstractWith the improvement of percutaneous coronary intervention (PCI), the miniaturization of devices has continued. We have developed a virtual 2‐Fr system that is the slenderest system to date. The outer diameter of the system using a 4‐Fr sheathless guiding catheter is ∼2‐Fr size. We report a case successfully treated using this new system. This novel virtual 2‐Fr system has the potential to provide less invasive PCI during vascular access and to reduce patient morbidity. © 2010 Wiley‐Liss, Inc.