bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seventeenth-century Seville houses: a survey by the Alarife Juan De Legarra (1637)
Authors: Moya-Olmedo Pilar , Núñez-González María , Vilaplana-Villajos Fernando 
Published: May 2024

AbstractDespite the wealth of preserved information, research on the domestic architecture of Seville has been limited. Much of this historical data is available in survey books that were formally compiled in Seville from the Modern Age onwards. These books had detailed descriptions and sometimes illustrations provided by surveyors who were commissioned by owners or tenants.The intention of this study is to illustrate that the information contained in building surveys goes beyond simple descriptions or measurements often accompanied by drawings. They are a comprehensive account that, even centuries later, help reconstruct the architecture, material culture and everyday life that no longer exist. Our research contributes to the understanding of the domestic architectural history of Seville by focusing on one specific survey (a collection of drawings and a written description) extracted from the Hospital de las Cinco Llagas Collection, which is found in the Seville Provincial Council Archive. At least one of the drawings and the written survey can be attributed to the Alarife (architect or master builder) Juan de Legarra, who signed them in 1637.This research explores the architectural development of the city, offering fresh insights into its architecture, heritage, and history. It supplements existing historical, visual, and written records derived from prior studies with a meticulously curated bibliography. Additionally, it uses visualisation techniques to reconstruct buildings, augmenting the research.This endeavour has yielded anticipated benefits, particularly in facilitating visual analysis. The surveys have proven to be invaluable for historical inquiry, yielding unexpected insights through the thorough analysis of both written and graphic sources which serve as a basis for hypothetical construction plans due to their detailed descriptions. Furthermore, this study has contributed to enriching both historical and architectural terminology.The incorporation of digital technologies into this architectural context allows us to expand our knowledge through the exhaustive compilation of building records. It also facilitates in-depth analysis of architecture, which could result in an up-to-date architectural catalogue that would stimulate interest in preserving a legacy that, until recently, was at risk of being lost.
Investigation on mechanical and thermal behaviour of graphene bonded carbon/Kevlar hybrid fabric polymer composites
Authors: Peddakondigalla Venkateswara Babu , Boggarapu Vasavi , Doppalapudi Rajani , N. Phani Pooja , Y. Aruna 
Published: May 2024

AbstractThe present research is aimed to understand the influence of graphene-reinforced carbon/Kevlar hybrid fabric epoxy composites. Samples HG0, HG2, HG4, and HG6 are fabricated using four layers of fabric mat and with varying graphene weight percentage as 0, 2, 4, and 6 wt.%, respectively. Mechanical characterizations such as hardness, tensile, and flexural strength were individually assessed. Thermal stability is evaluated through thermos-gravimetric analysis. Composite HG6 with high filler loading showed 71% and 114.4% greater tensile and flexural strength compared to unfilled HG0 specimen. Similarly, HG6 exhibited greater thermal stability. Inclusion of graphene particles in higher concentration improved the interfacial bonding between fibre/matrix/filler system. Fracture surfaces are analysed using scanning electron microscopy to understand the failure mechanisms.
Active sex life for older people in Chile: biological, psychological and social variables influencing engagement
Authors: Hinojosa Valentina 
Published: May 2024

Introduction:
Sexual activity in later life is increasingly being researched, but there is a gap in knowledge about the Global South, mainly Latin America.

Objective:
The objective of this article is to evaluate how biological, psychological and social factors influence active sex life in older Chilean people, using a gender-stratified analysis.

Methodology:
The study is based on secondary data analysis of the fifth National Survey of Quality of Life in Old Age, carried out in Chile in 2019 with a sample of 2,132 people aged 60 and over. Bivariate analysis was conducted to test the influence of biological, psychological and social variables on having an active sex life. Additionally, multiple hierarchal logistic regressions were carried out using a gender-stratified analysis to explore whether the independent variables predict active sex life.

Results:
Self-perceived health and chronic illness did not have predictive value regarding active sex life in older Chilean adults. However, partner health was a significant factor in predicting active sex life, particularly for women. People who reported being dissatisfied with life had 55 percent lower chance of having an active sex life than those who reported being very satisfied with life. Attitude towards sexuality, relationship status and education level were other variables that predicted an active sex life for older adults in Chile. Still, there were significant gender differences in the results.

Conclusion:
Interpersonal, psychological and social factors are more relevant than biological factors (except for age) when predicting sexual activity for older Chileans, and gender differences are central when analysing sexual activity.
Development and validation of machine learning models to predict unplanned hospitalizations of patients with diabetes within the next 12 months
Authors: Andreychenko A. E. , Ermak A. D. , Gavrilov D. V. , Novitskiy R. E. , Gusev A. V. 
Published: May 2024

BACKGROUND: The incidence of diabetes mellitus (DM) both in the Russian Federation and in the world has been steadily increasing for several decades. Stable population growth and current epidemiological characteristics of DM lead to enormous economic costs and significant social losses throughout the world. The disease often progresses with the development of specific complications, while significantly increasing the likelihood of hospitalization. The creation and inference of a machine learning model for predicting hospitalizations of patients with DM to an inpatient medical facility will make it possible to personalize the provision of medical care and optimize the load on the entire healthcare system.AIM: Development and validation of models for predicting unplanned hospitalizations of patients with diabetes due to the disease itself and its complications using machine learning algorithms and data from real clinical practice.MATERIALS AND METHODS: 170,141 depersonalized electronic health records of 23,742 diabetic patients were included in the study. Anamnestic, constitutional, clinical, instrumental and laboratory data, widely used in routine medical practice, were considered as potential predictors, a total of 33 signs. Logistic regression (LR), gradient boosting methods (LightGBM, XGBoost, CatBoost), decision tree-based methods (RandomForest and ExtraTrees), and a neural network-based algorithm (Multi-layer Perceptron) were compared. External validation was performed on the data of the separate region of Russian Federation.RESULTS: The best results and stability to external validation data were shown by the LightGBM model with an AUC of 0.818 (95% CI 0.802–0.834) in internal testing and 0.802 (95% CI 0.773–0.832) in external validation.CONCLUSION: The metrics of the best model were superior to previously published studies. The results of external validation showed the relative stability of the model to new data from another region, that reflects the possibility of the model’s application in real clinical practice.
The impact of innovative glucose-lowering drugs on the course and outcome of COVID-19 in patients with type 2 diabetes mellitus
Authors: Markova T. N. , Stas M. S. 
Published: May 2024

Patients with type 2 diabetes mellitus (T2DM) are at high risk of adverse outcomes in coronavirus infection (COVID-19). Despite the gradual resolution of the pandemic, new strains of the virus are emerging, characterized by high contagiousness, and the risk of infection becoming a seasonal disease is increasing. In this connection, the issue of identifying risk factors that aggravate the course of COVID-19 in patients with T2DM, including the role of initial hypoglycemic therapy, remains relevant.The review presents and systematizes up-to-date information (according to randomized clinical trials and meta-analyses) on the effect of outpatient and inpatient use of metformin and innovative hypoglycemic drugs (glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors) on the course and outcome of COVID-19 in patients with T2DM. At the same time, the potential mechanisms of the pathogenetic effect of drugs on the course of COVID-19, positive and negative aspects of their administration are described.
Молодежные лидеры в Краснодарском крае: профили, стратегии успеха и ресурсный потенциал
Authors: Мирошниченко Инна Валерьевна , Кольба Алексей Иванович , Самаркина Ирина Владимировна , Бориско Ольга Александровна 
Published: May 2024

В статье отражены результаты исследования субъектных характеристик молодежного лидерства в Краснодарском крае. Цель работы — оценить возможности включения молодежных лидеров в систему публичного управления развитием человеческого капитала в регионе. Междисциплинарная методология основана на сочетании социологического, психологического и политологического подходов к анализу молодежного лидерства. Применяется качественная стратегия эмпирического исследования, включающая в себя комплекс социологических методов сбора информации (фокус-групповые дискуссии, экспертные сессии, глубинные интервью).
Полученные результаты позволили уточнить содержание профилей молодежных лидеров («потребители» и «преобразователи»), различающихся ориентацией либо на собственное развитие, либо на решение общественных проблем. Охарактеризованы траектории развития молодежных лидеров (институционально-представительская, командная, «управление развитием» и др.) и выделены присущие им стратегии достижения успеха. Определены актуальные и латентные ресурсы, существующие в рамках двух типов лидерства, субъектные и объектные маркеры лидерства. В целом состояние молодежного лидерства в регионе по итогам проведенного исследования охарактеризовано как кризисное. Авторы приходят к выводу, что ресурсный потенциал молодежных лидеров может быть более полно использован для их интеграции в институты и практики публичного управления регионом.
Благодарность. Исследование «Молодежное лидерство в региональных практиках публичного управления развитием человеческого капитала: стратегии достижения успеха, возможности, результаты» выполнено в рамках государственного задания Министерства науки и высшего образования РФ (FZEN -2022-0013).
Nutritional and therapeutic potentials of Carica papaya Linn. seed: A comprehensive review
Authors: Adeoye Raphael Idowu , Olopade Esther Temidayo , Olayemi Ifeoluwa Oluwatosin , Okaiyeto Kunle , Akiibinu Moses Olayemi 
Published: May 2024

The health benefits and nutritional value of pawpaw or papaya (Carica papaya Linn.) are well established. The entire papaya plant—including the leaves, fruit, bark, root, juice, seeds and latex - is used for dietary, medicinal and other purposes. However, papaya seeds are the under-exploited part since they are typically seen as waste after the edible fruits have been processed and consumed. Hence, the aim of this review is to document the nutraceutical and therapeutic potential of Carica papaya seeds with a view of enhancing its prospect in drug development. The following title search criteria were used “Carica papaya” OR “Papaya” OR “Pawpaw OR C. papaya” AND “seed” OR “seed oil”; while “fruits OR leaves OR stem OR root OR juice OR latex” were excluded. The articles used for this research were limited to the original research articles and those written in English Language only. The seeds which are often seen as waste products offer countless possibilities for developing new nutritional supplements and medicines due to the huge vital micronutrients and a variety of secondary metabolites that have been reported to be embedded in them. Papaya seeds contain beneficial phytochemicals such as carotenoids, flavonoids, alkaloids, phytosterols and tocopherols. These substances, have intriguing nutraceutical qualities and are important in the treatment and amelioration of several medical disorders. Benzyl glucosinolates, caricin, fatty acids, crude fibre, carpaine, glucotropaeolin, benzyl isothiocyanate, crude protein, benzyl thiourea, hentriacontane, ß-sitostrol and enzymes (myrosinase and papain) were discovered as nutritional components in papaya seeds. Papaya seeds may be used medicinally as antioxidant, antidiabetic, antiulcerogenic, liver cirrhosis treatment and menstrual cycle modulation.
It takes a village
Authors: Smith Debborah 
Published: May 2024

Digital textbooks now incorporate various technological enhancements, and offer many opportunities for learning and teaching in higher education. Despite some enthusiasm for this medium, lecturers tend not to integrate the extra activities into their courses preferring instead to simply have them available as optional extra activities for students. One reason for this barrier to use is the time and effort required to integrate technology into the curriculum in a meaningful way, and lecturers may feel they lack the necessary knowledge to do this effectively. Despite the existence of institutional support to assist educators with technology enhanced learning, the services don’t always align with what faculty want or need. As a result, there have been calls to improve staff training and professional development. This paper presents a theorised inquiry into educators’ reflections on the integration of digital textbooks using Mishra & Koehler’s TPACK framework as an underpinning theory. The findings suggest the need for training and support that is individualised to instructors’ specific needs, and allows for increased collaboration between various stakeholders. It is concluded that professional development that focusses on the development of TPACK, and operates within a collaborative and context-specific learning community could support the increased uptake of digital textbooks in higher education.
A novel iterative process for numerical reckoning of fixed points via generalized nonlinear mappings with qualitative study
Authors: Ahmad Fayyaz , Ullah Kifayat , Ahmad Junaid , Hammad Hasanen A. , George Reny 
Published: May 2024

Abstract
This manuscript is devoted to constructing a novel iterative scheme and reckoning of fixed points for generalized contraction mappings in hyperbolic spaces. Also, we establish

Δ

\Delta

and strong convergence results by the considered iteration under the class of mappings satisfying condition (E). Moreover, some qualitative results of the suggested iteration, like weak

w

2

{w}^{2}

-stability and data dependence results, are discussed. Furthermore, to test the efficiency and effectiveness of the proposed iteration, practical experiments are given. To support the theoretical results, illustrative examples are presented. Finally, our results improve and generalize several classical results in the literature of fixed point iterations.
Using interpretative structure model and analytical network process for optimum site selection of airport locations in Delta Egypt
Authors: Beshr Ashraf A. A. , Basha Ali M. , Lofty Nourhan , Farhan Magda H. 
Published: May 2024

Abstract
Airports are among the constructions that must meet international standards and specifications established by the International Civil Aviation Organization (ICAO). Some of these parameters and criteria include topography, environmental, and operating circumstances. Navigation operations are also affected by terrain and human barriers, while noise, infrastructure, and weather factors affect the environment around airports. This article investigates using the interpretative structure model (ISM) and analytical network process (ANP) together as a new technique to select and determine the optimum site selection for constructing new international airports in the Nile Delta, Egypt. The criteria used (16 international criteria) are selected depending on the standards of the ICAO, field surveys, and previous studies. Nile Delta, Egypt, is chosen as a case study because it suffers from the lack of international airports and has a population of approximately 23 million. Therefore, new international airports must be established to serve this region, boost tourism, improve transportation, and stimulate commercial traffic. The results using the suggested new technique are compared with the traditional used methods for site selection, such as fuzzy-analytic hierarchy process. Landsat 8 images are used in this research. A quality test using the area under the curve and the receiver operating characteristic curve was applied to evaluate the new technique for site selection of international airports, depending on calculating the highest suitability index for each proposed site. From the quality tests, it is deduced that the suggested method (ISM–ANP) for airport site selection is more accurate than any other traditional method. ArcGIS 10.5 software is used to draw the final digital maps containing the proposed resulted sites. As a result, three new locations for the construction of international airports were found and selected throughout the research region (Delta Nile, Egypt) based on the used mathematical models. Therefore, the proposed novel method for determining the locations of international airports is thought to be effective and feasible, and it can be used to determine the locations of any development projects in general, particularly in developing countries, which benefits the decision-makers in making the right decisions.
Epenthetic vowel quality crosslinguistically, with focus on Modern Hebrew
Authors: Faust Noam 
Published: May 2024

Abstract
This paper proposes the principle of weakest epenthesis, whereby the quality of the epenthetic vowel is that of the weakest lexical vowel of the language, and weakness is defined phonologically, not phonetically. This principle is first shown to motivate the emergence of [e] as the epenthetic vowel of Modern Hebrew. It is then corroborated by a crosslinguistic survey of 100 languages. Finally, the Modern Hebrew facts are used to illustrate the formalization of this principle using gradient symbolic representations.
Comprehensive analysis of competing endogenous RNA networks involved in the regulation of glycolysis in clear cell renal cell carcinoma
Authors: Gao Shenglin , Shi Xiaokai , Yue Chuang , Chen Yin , Zuo Li , Wang Simin 
Published: May 2024

Abstract

Objectives
This study aims to elucidate the role of competing endogenous RNAs (ceRNAs), which are pivotal in the post-transcriptional regulation of cancer cells, in the glycolysis of clear cell renal cell carcinoma (ccRCC).

Methods
RNA-seq data from ccRCC samples and public datasets were subjected to differential expression analysis to identify the upregulated circular RNAs (circRNAs), long noncoding RNAs (lncRNAs), and mRNAs for constructing a ceRNA network. This network focused on the upregulated mRNAs linked to glycolysis and gluconeogenesis, which were verified at the proteome level using the CPTAC database. The ENCORI database was used to predict the lncRNA/circRNA-miRNA and miRNA-mRNA interactions, which formed a network visualized using Cytoscape. This study further examined the association of selected lncRNAs/circRNAs with biological processes and patient survival and explored lncRNA and mRNA expressions at the single-cell level.

Results
Three circRNAs and eight lncRNAs were identified to be regulators of four glycolysis pathway genes (HK2, LDHA, PFKP, and ALDOC) via 54 miRNAs. Notably, their expressions were aberrant at the transcriptome and proteome levels. These RNA elements were correlated with malignant and immune pathways, and several lncRNAs showed prognostic significance for ccRCC. Furthermore, single-cell RNA sequencing indicated the abnormal enrichment of these lncRNAs and mRNAs in malignant cells.

Conclusions
This study identified a ceRNA network that plays a critical role in the glycolysis of ccRCC. These findings highlight the importance of ceRNAs in cancer malignancy and their potential impact on patient prognosis.
Managing Dust in Academic Libraries
Authors: Rasaki Ejiwoye Oluwole , Ogunmodede Thomas A. , Adedimeji Akeem Adedayo 
Published: May 2024

Abstract
The study investigates dust management at the Albert Ilemobade library, The Federal University of Technology Akure. Dust deposition and accumulation poses a major challenge for the university library as all the units, sections, and divisions are affected. Dust not only adversely affects all materials, equipment, and facilities including books, audiovisual collections, and computers, but also constitutes a health hazard to library personnel and users. Major sources of dust include visitor activities and infiltration through openings like windows and doors. Dust mats, special computer enclosures, dusters, dust blowers, and respiratory masks were made available for dust protection and management in the library. The library lacked equipment like High Efficiency Particulate Arresting (HEPA) filters and dust collection, and suppressions systems. Lack of awareness and training, inadequate funding, and lack of equipment were identified as the challenges to dust management in the library.
On the Reversibility of Spray Adhesives in Paper Conservation
Authors: Muñoz-Viñas Salvador , Sobrino-Estalrich María 
Published: May 2024

Abstract
This research explores the practical advantages and potential applications of spray adhesives, focusing on testing their suitability for artwork mounting uses. Their solubility in common low-toxicity solvents (ethanol and acetone) was evaluated. Seven commercial spray adhesives from different commercial brands and compositions were applied on paper samples and subjected to different ageing conditions. The samples were then immersed in the solvent, and the degree of adhesive removal was measured. One of the most relevant conclusions is that commercial neoprene-based spray adhesives become brittle and fragile in a few weeks, which makes them unsuitable for both long-term and temporary applications in the heritage field. On the other hand, the solubility was high or very high in some cases: up to 98 % of adhesive removal was achieved in acetone wash. These tests and the convenience, cost and availability of spray adhesives suggest that some of them may be safely used in some scenarios such as temporary mountings or transport.