bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: N‐Benzyl‐Protection of Amino Acid Derivatives by Reductive Alkylation with α‐Picoline‐Borane.
Authors: Kawase Yasushi , Yamagishi Takehiro , Kutsuma Teruo , Kataoka Tadashi , Ueda Kimio , Iwakuma Takeo , Nakata Tadashi , Yokomatsu Tsutomu 
Published: September 2010

AbstractA convenient method is presented using PBH as a safe non‐explosive reducing agent.
ChemInform Abstract: A Mild and Efficient Synthetic Protocol for Ferrier Azaglycosylation Promoted by ZnCl2/Al2O3.
Authors: Ding Feiqing , William Ronny , Gorityala Bala Kishan , Ma Jimei , Wang Siming , Liu Xue‐Wei 
Published: September 2010

AbstractThe method affords the products with high α‐selectivity.
ChemInform Abstract: Regioselective Reductive Ring Opening of Benzylidene Acetals Using Triethylsilane and Iodine.
Authors: Panchadhayee Rajib , Misra Anup Kumar 
Published: September 2010

AbstractNovel mild conditions are developed which are compatible to a broad spectrum of functional groups in oligosaccharide synthesis and can also be applied to thioglycosides and selenium analogues.
ChemInform Abstract: Synthesis of Methyl 4‐O‐Methyl‐β‐D‐ribo‐hex‐3‐ulopyranoside‐1‐13C and Methyl 4‐O‐Methyl‐β‐D‐ribo‐hex‐3‐ulopyranoside‐3‐13C as Fragment Analogues of Oxidized Cellulose Units.
Authors: Krainz Karin , Hofinger Andreas , Dietz Thomas , Suess Hans‐Ulrich , Potthast Antje , Rosenau Thomas 
Published: September 2010

AbstractTo ensure the synthetic approach to the labeled title compounds, the route is optimized with non‐labeled material according to the scheme.
ChemInform Abstract: Substrate‐Controlled Stereoselective Synthesis of Ophiocerin C.
Authors: Yadav Jhillu S. , Reddy N. Rami , Krishna B. Bala Murali , Vardhan Ch. Vijaya , Reddy Basi V. Subba 
Published: September 2010

AbstractThe readily available L‐tartaric acid derivative (I) is transformed to the alkene (II).
ChemInform Abstract: Geranyl Derivatives of Isoquinoline Alkaloids Show Increased Biological Activities.
Authors: Iwasa Kinuko , et al. et al. 
Published: September 2010

AbstractThree types of isoquinoline alkaloids are synthesized and tested for antimicrobial, cytotoxic, antimalarial, antioxidant and anti‐HIV activities as well as inhibition of EBV‐EA activation.
ChemInform Abstract: Practical and Efficient Synthesis of Pyrano[3,2‐c]pyridone, Pyrano[4,3‐b]pyran and Their Hybrids with Nucleoside as Potential Antiviral and Antileishmanial Agents.
Authors: Fan Xuesen , Feng Dong , Qu Yingying , Zhang Xinying , Wang Jianji , Loiseau Philippe M. , Andrei Graciela , Snoeck Robert , De Clercq Erik 
Published: September 2010

AbstractA novel, green and efficient method for the synthesis of the title pyranopyridone and pyranopyran derivatives using a one‐pot three‐component reaction is developed.
ChemInform Abstract: Total Synthesis of Graphislactone G.
Authors: Cudaj Judith , Podlech Joachim 
Published: September 2010

AbstractThe synthesis of title compound (V), a constituent of the endophytic fungus Cephalosporium acremonium (IFB‐E007), is completed in 13 steps and 22% yield starting from orcinol (I) and phloroglucinic acid.
ChemInform Abstract: First Total Synthesis and Structural Confirmation of Fluvirucinine A2 via an Iterative Ring Expansion Strategy.
Authors: Lee Yong‐Sil , Jung Jong‐Wha , Kim Seok‐Ho , Jung Jae‐Kyung , Paek Seung‐Mann , Kim Nam‐Jung , Chang Dong‐Jo , Lee Jeeyeon , Suh Young‐Ger 
Published: September 2010

AbstractThe total synthesis is achieved by the multiple application of a ring‐expansion reaction, mediated by LiN(Tms)2.
ChemInform Abstract: Side Chain SAR of Bicyclic β‐Lactamase Inhibitors (BLIs). Part 1. Discovery of a Class C BLI for Combination with Imipinem.
Authors: Blizzard Timothy A. , et al. et al. 
Published: September 2010

AbstractBridged monobactam β‐lactamase inhibitors containing seven‐, eight‐ and nine‐membered moieties are prepared and evaluated as potential partners for combination with imipenem to overcome class C β‐lactamase mediated resistance.
ChemInform Abstract: Catalytic Activity Studies of Aminocarbonyl Group Containing Hoveyda—Grubbs‐Type Complexes for the Syntheses of Herbarumin I (IV) and Stagonolide A (V).
Authors: Mohapatra Debendra K. , Somaiah R. , Rao M. Mallikarjuna , Caijo Frederic , Mauduit Marc , Yadav J. S. 
Published: September 2010

AbstractIt is demonstrated that the “boomerang”‐type catalysts are more efficient than the standard types for the preparation of key intermediate (III).
ChemInform Abstract: Artosimmin — A Potential Anticancer Lead Compound from Artocarpus odoratissimus.
Authors: Ee Gwendoline C. L. , Teo Siow H. , Rahmani Mawardi , Lim Chan K. , Lim Yang M. , Bong Choon F. J. 
Published: September 2010

AbstractArtosimmin (I) is significantly cytotoxic against cell lines HL‐60 and MCF‐7 and possesses antioxidant properties towards DPPH.
ChemInform Abstract: The First Kinetic Enzymatic Resolution of Methyl Ester of C75.
Authors: Chakrabarty Kuheli , Forzato Cristina , Nitti Patrizia , Pitacco Giuliana , Valentin Ennio 
Published: September 2010

AbstractEnantioselective hydrolysis of the methyl ester of racemic paraconic acid C75 (I) is accomplished by means of acylase I from Aspergillus to afford after recrystallization enantiopure acid (II).
ChemInform Abstract: Synthesis of 4′‐Ester Analogues of Resveratrol and Their Evaluation in Malignant Melanoma and Pancreatic Cell Lines.
Authors: Wong Yong , Osmond Gregory , Brewer Kenneth I. , Tyler Douglas S. , Andrus Merritt B. 
Published: September 2010

AbstractEster analogues (IV) of resveratrol are synthesized from resorcylic acid using a decarbonylative Heck coupling as key step.
ChemInform Abstract: Intramolecular Triarylmethane—Triarylmethylium Complex: Generation, Properties, and X‐Ray Structure of a C—H‐Bridged Carbocation
Authors: Suzuki Takanori , Takeda Takashi , Yoshimoto Yasuyo , Nagasu Takayuki , Kawai Hidetoshi , Fujiwara Kenshu 
Published: September 2010

AbstractReview: 49 refs.
ChemInform Abstract: Radical‐Substituted Dihydrophenazine Radical Cation Salts: Molecular Packing Structure and Bulk Magnetic Property
Authors: Masuda Yuki , Takeda Hirotaka , Kuratsu Masato , Suzuki Shuichi , Kozaki Masatoshi , Shiomi Daisuke , Sato Kazunobu , Takui Takeji , Okada Keiji 
Published: September 2010

AbstractReview: 18 refs.
ChemInform Abstract: Magnetic Quantum Tunneling: Insights from Simple Molecule‐Based Magnets
Authors: Hill Stephen , Datta Saiti , Liu Junjie , Inglis Ross , Milios Constantinos J. , Feng Patrick L. , Henderson John J. , del Barco Enrique , Brechin Euan K. , Hendrickson David N. 
Published: September 2010

AbstractReview: 76 refs.
ChemInform Abstract: Mechanisms for Formation, Chlorination, Dechlorination and Destruction of Polychlorinated Dibenzo‐p‐dioxins and Dibenzofurans (PCDD/Fs)
Authors: Altarawneh Mohammednoor , Dlugogorski Bogdan Z. , Kennedy Eric M. , Mackie John C. 
Published: September 2010

AbstractReview: 240 refs.
Balancing the harms and benefits of early detection of prostate cancer
Authors: van Leeuwen Pim J. , Connolly David , Tammela Teuvo L. J. , Auvinen Anssi , Kranse Ries , Roobol Monique J. , Schroder Fritz H. , Gavin Anna 
Published: September 2010

AbstractBACKGROUND:The benefits of prostate cancer screening on an individual level remain unevaluated.METHODS:Between 1993 and 1999, a total of 43,987 men, aged 55‐74 years, were included in the intervention arm of the European Randomized Study of Screening for Prostate Cancer (ERSPC) section in the Netherlands, Sweden, and Finland. A total of 42,503 men, aged 55‐74 years, were included in a clinical population in Northern Ireland. Serum prostate‐specific antigen (PSA) <20.0 ng/mL was measured in all men at study entry. All men were followed for prostate cancer incidence and causes of death until December 31, 2006.RESULTS:The adjusted absolute difference in prostate cancer specific mortality between the intervention population and the clinical population increased with increasing PSA level at study entry, ie, 0.05 per 10,000 person‐years for men who had a serum PSA level of 0.0‐1.9 ng/mL and 8.8 per 10,000 person‐years for men who had a serum PSA level of 10‐19.9 ng/mL. To evaluate the risks of early detection, the number needed to investigate (NNI) and number needed to treat (NNT) to save 1 death from prostate cancer were calculated. Both NNI and NNT were higher for those who had lower PSA levels at study entry. The NNI was 24,642 men for patients who had a serum PSA level of 0.0‐1.9 ng/mL and was 133 men for patients who had a serum PSA level of 10‐19.9 ng/mL; the NNT was 724 men for patients who had a serum PSA level of 0.0‐1.9 ng/mL and was 60 men for patients with a serum PSA level of 10‐19.9 ng/mL.CONCLUSIONS:For men with a low serum PSA level, the benefits of aggressive investigation and treatment may be limited because they are associated with a large increase in cumulative incidence and potential overtreatment. Cancer 2010. © 2010 American Cancer Society.
Molecular Encapsulation of Fluorescent Dyes Affords Efficient Narrow‐band Dye Laser Operation in Water
Authors: Mohanty Jyotirmayee , Jagtap Krishna , Ray Alok K. , Nau Werner M. , Pal Haridas 
Published: September 2010

AbstractA water‐based narrow‐band high‐efficiency dye laser was designed by means of a supramolecular host–guest chemical approach. The lasing characteristics of rhodamine B and sulforhodamine B (Kiton Red S) dyes in aqueous solution with the macrocyclic host cucurbit[7]uril (CB7) as additive were investigated in a narrow‐band dye laser setup. Significant improvements in both photostability and thermo‐optical properties of the aqueous CB7‐complexed dye systems were observed as compared to the uncomplexed dyes in ethanol solution. The tuning curves for the new dye–CB7–water systems were constructed by measuring the laser output at different wavelengths, which showed similar peak efficiencies and red‐shifted gains compared to the ethanolic solutions of the dyes, while dye laser operation revealed comparable pump threshold energies and slope efficiencies. The combined results render the dye–CB7–water system an attractive active medium for high‐repetition rate dye laser operation.
Exploring parents' attitudes and behaviors about their children's physical appearance
Authors: Striegel‐Moore Ruth H. , Kearney‐Cooke Ann 
Published: September 2010

AbstractThis survey study provides descriptive information regarding parents' evaluations of children's physical appearance, eating habits and exercise behaviors, and of parental efforts to influence their children's physical appearance. It further tests hypotheses of gender‐related differences and age effects in parents' evaluations of their children. The study sample included 1,276 adult men and women who were selected from the participants of a body image survey. To be included, respondents had to be a parent of a child between the ages of 2 years and 16 years. A majority of respondents were found to be basically satisfied with their child's physical appearance, eating habits, and exercise behavior. However, increasingly less positive evaluations were reported with increasing age of the child. This shift in attitude was observed already among parents of grade schoolers. Few gender‐related differences were found between male and female respondents, although women appeared to be more involved in influencing children's appearance. Analyses exploring differences concerning gender of the child found mixed results. Some questions resulted in gender‐related differences consistent with the greater importance of beauty for women compared with men, yet our data also suggested that increasingly, men are included in our culture's mandate to value and pursue physical attractiveness.
Case study of the effects of prolonged and severe anorexia nervosa on bone mineral density
Authors: Kotler Lisa , Katz Lee , Anyan Walter , Comite Florence 
Published: September 2010

AbstractAmong the most severe sequelae of anorexia nervosa (AN) are its skeletal complications. Young women who have AN during adolescence may not attain their expected peak skeletal mass, and may enter adulthood with reduced bone mineral density (BMD) and an increased risk of fracture. This case history describes a young woman with severe AN that included prolonged exposure to both low body weight and amenorrhea. BMD measurement during the acute stage of her illness revealed severe osteopenia. Six years after recovery from AN, follow‐up studies demonstrated only modest gains in BMD, with measurements for the hip and lumbar spine that are greater than 2 SDs below the age‐matched mean.
Changes in eating inventory scores following obesity treatment
Authors: Clark Matthew M. , Marcus Bess H. , Pera Vincent , Niaura Raymond S. 
Published: September 2010

AbstractEating Inventory scores may predict compliance, attrition, and outcome to obesity treatment. Research documenting change on the Eating Inventory subsequent to treatment is limited. In Study 1, 29 obese patients demonstrated significant improvement on all three factors of the Eating Inventory (Cognitive Restraint, Disinhibition, and Hunger) following a 26‐week multidisciplinary weight management program. In Study 2, a second sample of 18 obese patients also demonstrated significant improvement on all three factors on the Eating Inventory following treatment. These results provide initial guidelines for the amount of change that patients may demonstrate on the Eating Inventory following treatment.
Li2CaSi2N4 and Li2SrSi2N4 – a Synthetic Approach to Three‐Dimensional Lithium Nitridosilicates
Authors: Zeuner Martin , Pagano Sandro , Hug Stephan , Pust Philipp , Schmiechen Sebastian , Scheu Christina , Schnick Wolfgang 
Published: September 2010

AbstractThe quaternary lithium alkaline earth nitridosilicatesLi2MSi2N4 with M = Ca, Sr were synthesized at 900 °C by employment of liquid lithium as fluxing agent in weld shut tantalum ampoules. The title compounds crystallize in space group Pa$\bar {3}$ [Li2CaSi2N4: a = 1056.9(12) pm, Z = 12, R1 = 0.0439, wR2 = 0.0839, 412 data, 42 parameters; Li2SrSi2N4: a = 1071.37(12) pm, Z = 12, R1 = 0.0476, wR2 = 0.1227, 528 data, 42 parameters]. The structure is built up from vertex sharing [SiN4] tetrahedra forming a three‐dimensional network comprising the alkaline earth and lithium ions in the voids. The network is the first example of a nitridosilicate adopting topology of Net 39 according to O'Keeffe. The two crystallographically independent M2+ sites are highly symmetrically coordinated by six nitrogen atoms. Lattice energy calculations (MAPLE) and EDX measurements confirmed the electrostatic bonding interactions and the chemical compositions. 7Li and 29Si solid‐state MAS NMR spectra of Li2SrSi2N4 are reported. Electron energy‐loss spectroscopy (EELS) elucidates further information upon the lithium incorporation.
Ring‐Opening Reaction of Methylenecyclopropanes Derived from Methylenecyclopropyl Aldehydes through Cope Rearrangement
Authors: Tang Xiang‐Ying , Wei Yin , Shi Min 
Published: September 2010

AbstractTandem Wittig reaction/Cope rearrangement of methylenecyclopropyl aldehydes 1 with cinnamyltriphenylphosphonium bromide afforded a convenient method for the synthesis of cyclopentene derivatives 2 in moderate yields in a one‐pot manner. Dialkyl 2‐[(2‐methylenecyclopropyl)methylene]malonates 3 derived from methylenecyclopropyl aldehydes 1 could produce two kinds of cyclopentene derivatives, 4 and 5, in good total yields through a thermally induced Cope rearrangement upon heating at 100 °C. Plausible reaction mechanisms are discussed on the basis of previous reports and on control experiments.
Preparation of Sugar β‐Amino Acid Derivatives with Cyclic Structures by Ring‐Closing Metathesis
Authors: Sundararaju Basker , Sridhar Tailor , Achard Mathieu , Sharma Gangavaram V. M. , Bruneau Christian 
Published: September 2010

AbstractEfficient syntheses of β‐amino acid derivatives with cyclic structures were developed. The key steps involve aza‐Michael addition and ruthenium‐catalyzed allylation for the construction of new acyclic β‐amino acid dienes incorporating a sugar fragment, and a ruthenium‐catalyzed ring‐closing metathesis for the construction of the seven‐ and nine‐membered ring compounds.
Straightforward Synthesis of Diverse 1‐Deoxyazapyranosides via Stereocontrolled Nucleophilic Additions to Six‐Membered Cyclic Nitrones
Authors: Chan Ting‐Hao , Chang Yi‐Fan , Hsu Jung‐Jung , Cheng Wei‐Chieh 
Published: September 2010

AbstractA systematic study of diastereoselective nucleophilic addition of Grignard reagents to six‐membered chiral tri‐O‐benzyl cyclic nitrones is described. With all eight chiral cyclic nitrones and asymmetric reaction conditions in hand, a practical methodology is established for the preparation of diverse 1‐deoxyazapyranosides bearing various stereogenic centers.
Development of the core‐suspended isolation system
Authors: Nakamura Yutaka , Saruta Masaaki , Wada Akira , Takeuchi Toru , Hikone Shigeru , Takahashi Teiichi 
Published: September 2010

AbstractA new type of seismic isolation system—called the core‐suspended isolation (CSI) system—has been developed and first building application recently completed. The CSI system consists of a reinforced concrete core on top of which a seismic isolation mechanism composed of a double layer of inclined rubber bearings is installed to create a pendulum isolation mechanism. A multi‐level structure is then suspended from a hat‐truss or an umbrella girder constructed on the seismic isolation mechanism. In this paper, the mechanics of the CSI system are described, followed by a discussion of results of shaking table tests and quasi‐static loading tests of rubber bearings with rotated flanges, and a description of the first building constructed utilizing the CSI system, located in Tokyo, Japan. Copyright © 2010 John Wiley & Sons, Ltd.
Critical development? Using a critical theory lens to examine the current role of evaluation in the youth‐development field
Authors: Zeller‐Berkman Sarah 
Published: September 2010

AbstractA critical theory lens is used to explore the role of evaluation in youth development, a field aimed at recognizing youth as assets. A theory of change in the field is questioned for its emphasis on individual youth outcomes as programmatic outcome measures. A review of 209 evaluations of 131 programs in the Harvard Family Research Project's Out‐of‐School Time Program Research and Evaluation Database reveals an overemphasis on individual gains related to academic achievement or youth development and a lack of attention to community‐ or systems‐level outcomes. The author posits that a critical approach would press evaluators to be intentional about what they measure and how in order to challenge the status quo for young people. © Wiley Periodicals, Inc., and the American Evaluation Association.
Moral knowledge and responsibilities in evaluation implementation: When critical theory and responsive evaluation collide
Authors: Freeman Melissa , Preissle Judith , Havick Steven 
Published: September 2010

AbstractAn external evaluation documented what occurred in an inaugural summer camp to teach high school students how to preserve religious freedom by learning about and acting on the history and current state of church–state separation and other first amendment issues. Camp designers hoped to promote religious diversity values and civic engagement in youth. An analytic vignette grounded in an inductive analysis of observations, interviews, and document collection represents the competing demands of responsive and critical approaches to evaluation. Balancing obligations to promote the social well‐being of society with responsibilities to clients and other stakeholders presents challenges that can be met only by identifying priorities with clients in ongoing dialogue. © Wiley Periodicals, Inc., and the American Evaluation Association.
Critical social theory evaluation: Slaying the dragon
Authors: Mabry Linda 
Published: September 2010

AbstractValues underlie evaluations, but there is no consensus as to whose values should found evaluators' judgments of program quality. The controversial position of critical social theory evaluators—that societal values trump those of evaluation commissioners—is explored in terms of professional issues and standards, historical evolutions, philosophical trajectories, and social responsibility. Attention is given to risks, compensations, and opportunity costs associated with taking (or not) a critical social theory approach to evaluation. © Wiley Periodicals, Inc., and the American Evaluation Association.
Near‐isochemical evolution of clay mineral assemblages in differentially buried volcaniclastic sediments, the Late Miocene Upper Red Formation, Iran
Authors: Amini A. , Curtis C. D. , Anketell J. M. 
Published: September 2010

AbstractThe Upper Red Formation (URF) comprises over 1–5 km of late Miocene siliciclastic sediments in the Central Iran Basin. The formation is dominated by volcaniclastic conglomerates and arenites. The prevailing arid conditions during most of the basin's history resulted in deposition of predominantly organic‐poor, red sediments with gypsum and zeolites. This investigation concentrates on the mineralogy and geochemistry of the URF in the southern and northern margins of the basin where the formation was buried to depths of 2.4 and 6.6 km, respectively. Fine fraction mineral separates from the southern margin consist of nearly pure smectite and zeolites at a depth of 400 m and smectite with minor quartz and calcite at 1800 m. Shallow samples (1350 m) from the northern section are rich in smectite, illite/smectite with some discrete illite and chlorite. This assemblage is progressively replaced by discrete illite and chlorite with increasing burial depth so that only these two minerals are found at depths greater than 4300 m. The initial alteration process involved replacement of glass and volcanic lithics by smectite and zeolites in both margins of the basin. Increased depth of burial in the northern margin resulted in the progressive isochemical alteration of smectite to discrete illite and chlorite. Diagenesis of clay assemblages occurred essentially in a closed system. Solute products of glass hydrolysis reactions were retained in highly alkaline, saline ground waters from which zeolites, carbonates and oxides precipitated as cements. It is unlikely that these sediments were ever significantly leached by meteoric waters or by organic acids generated during burial diagenesis. Copyright © 2010 John Wiley & Sons, Ltd.
The role of calcium release activated calcium channels in osteoclast differentiation
Authors: Zhou Yandong , Lewis Tricia L. , Robinson Lisa J. , Brundage Kathy M. , Schafer Rosana , Martin Karen H. , Blair Harry C. , Soboloff Jonathan , Barnett John B. 
Published: September 2010

AbstractOsteoclasts are specialized macrophage derivatives that secrete acid and proteinases to mobilize bone for mineral homeostasis, growth, and replacement or repair. Osteoclast differentiation generally requires the monocyte growth factor m‐CSF and the TNF‐family cytokine RANKL, although differentiation is regulated by many other cytokines and by intracellular signals, including Ca2+. Studies of osteoclast differentiation in vitro were performed using human monocytic precursors stimulated with m‐CSF and RANKL, revealing significant loss in both the expression and function of the required components of store‐operated Ca2+ entry over the course of osteoclast differentiation. However, inhibition of CRAC using either the pharmacological agent 3,4‐dichloropropioanilide (DCPA) or by knockdown of Orai1 severely inhibited formation of multinucleated osteoclasts. In contrast, no effect of CRAC channel inhibition was observed on expression of the osteoclast protein tartrate resistant acid phosphatase (TRAP). Our findings suggest that despite the fact that they are down‐regulated during osteoclast differentiation, CRAC channels are required for cell fusion, a late event in osteoclast differentiation. Since osteoclasts cannot function properly without multinucleation, selective CRAC inhibitors may have utility in management of hyperresorptive states. J. Cell. Physiol. 226: 1082–1089, 2011. © 2010 Wiley‐Liss, Inc.