bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential therapeutic effects of traditional Chinese medicine in acute mountain sickness: pathogenesis, mechanisms and future directions
Authors: Wu Zhenhui , Wang Yihao , Gao Rong , Chen Junru , Chen Yingfan , Li Maoxing , Gao Yue 
Published: June 2024

Background and objectivesAcute mountain sickness (AMS) is a pathology with different symptoms in which the organism is not adapted to the environment that occurs under the special environment of high altitude. Its main mechanism is the organism’s tissue damage caused by acute hypobaric hypoxia. Traditional Chinese medicine (TCM) theory focuses on the holistic concept. TCM has made remarkable achievements in the treatment of many mountain sicknesses. This review outlines the pathogenesis of AMS in modern and traditional medicine, the progress of animal models of AMS, and summarizes the therapeutic effects of TCM on AMS.MethodsUsing the keywords “traditional Chinese medicine,” “herbal medicine,” “acute mountain sickness,” “high-altitude pulmonary edema,” “high-altitude cerebral edema,” “acute hypobaric hypoxia,” and “high-altitude,” all relevant TCM literature published up to November 2023 were collected from Scopus, Web of Science, PubMed, and China National Knowledge Infrastructure databases, and the key information was analyzed.ResultsWe systematically summarised the effects of acute hypobaric hypoxia on the tissues of the organism, the study of the methodology for the establishment of an animal model of AMS, and retrieved 18 proprietary Chinese medicines for the clinical treatment of AMS. The therapeutic principle of medicines is mainly invigorating qi, activating blood and removing stasis. The components of botanical drugs mainly include salidroside, ginsenoside Rg1, and tetrahydrocurcumin. The mechanism of action of TCM in the treatment of AMS is mainly through the regulation of HIF-1α/NF-κB signaling pathway, inhibition of inflammatory response and oxidative stress, and enhancement of energy metabolism.ConclusionThe main pathogenesis of AMS is unclear. Still, TCM formulas and components have been used to treat AMS through multifaceted interventions, such as compound danshen drip pills, Huangqi Baihe granules, salidroside, and ginsenoside Rg1. These components generally exert anti-AMS pharmacological effects by inhibiting the expression of VEGF, concentration of MDA and pro-inflammatory factors, down-regulating NF-κB/NLRP3 pathway, and promoting SOD and Na + -K + -ATPase activities, which attenuates acute hypobaric hypoxia-induced tissue injury. This review comprehensively analyses the application of TCM in AMS and makes suggestions for more in-depth studies in the future, aiming to provide some ideas and insights for subsequent studies.
Transdiagnostic markers across the psychosis continuum: a systematic review and meta-analysis of resting state fMRI studies
Authors: Merola Giuseppe Pierpaolo , Tarchi Livio , Saccaro Luigi F. , Delavari Farnaz , Piguet Camille , Van De Ville Dimitri , Castellini Giovanni , Ricca Valdo 
Published: June 2024

Psychotic symptoms are among the most debilitating and challenging presentations of severe psychiatric diseases, such as schizophrenia, schizoaffective, and bipolar disorder. A pathophysiological understanding of intrinsic brain activity underlying psychosis is crucial to improve diagnosis and treatment. While a potential continuum along the psychotic spectrum has been recently described in neuroimaging studies, especially for what concerns absolute and relative amplitude of low-frequency fluctuations (ALFF and fALFF), these efforts have given heterogeneous results. A transdiagnostic meta-analysis of ALFF/fALFF in patients with psychosis compared to healthy controls is currently lacking. Therefore, in this pre-registered systematic review and meta-analysis PubMed, Scopus, and Embase were searched for articles comparing ALFF/fALFF between psychotic patients and healthy controls. A quantitative synthesis of differences in (f)ALFF between patients along the psychotic spectrum and healthy controls was performed with Seed-based d Mapping, adjusting for age, sex, duration of illness, clinical severity. All results were corrected for multiple comparisons by Family-Wise Error rates. While lower ALFF and fALFF were detected in patients with psychosis in comparison to controls, no specific finding survived correction for multiple comparisons. Lack of this correction might explain the discordant findings highlighted in previous literature. Other potential explanations include methodological issues, such as the lack of standardization in pre-processing or analytical procedures among studies. Future research on ALFF/fALFF differences for patients with psychosis should prioritize the replicability of individual studies.Systematic review registrationhttps://osf.io/, identifier (ycqpz).
The Iridescent Painting Palette of Michelino da Besozzo: First Results of Non-Invasive Diagnostic Analyses
Authors: Delle Foglie Anna , Felici Anna Candida 
Published: June 2024

This study concerns the characterization of the color palette of Michelino da Besozzo, one of the leading painters and illuminators of the Late Gothic period in Northern Italy. The artist’s relationship with the color blue was investigated by considering the recipe for lapis lazuli given by the artist to Giovanni Alcherio in Venice in 1410 and found in the medieval treatise of Jean Lebegue. The paper highlights this important evidence for the study of painting technique in the first half of the 15th century with an analytical and technical study of two paintings: The Mystic Marriage of Saint Catherine (Siena, Pinacoteca Nazionale, inv. 171) and The Madonna of the Rose Garden (Verona, Museo di Castelvecchio, inv. 173-1B359). These two case studies were approached through analyses carried out with non-invasive and portable techniques such as Energy Dispersive X-ray Fluorescence (ED-XRF) spectroscopy and Fiber Optics Reflectance Spectroscopy (FORS). The results show a color palette based on ultramarine, azurite, verdigris or copper resinate; earths, cinnabar or vermillion; and lead white, yellow and red ochre and lac. These preliminary results made it possible to clarify certain aspects of the artist’s style and his painting technique and identify common elements between the two works of art.
Simultaneous Formate and Syngas Conversion Boosts Growth and Product Formation by Clostridium ragsdalei
Authors: Schwarz Irina , Angelina Angelina , Hambrock Philip , Weuster-Botz Dirk 
Published: June 2024

Electrocatalytic CO2 reduction to CO and formate can be coupled to gas fermentation with anaerobic microorganisms. In combination with a competing hydrogen evolution reaction in the cathode in aqueous medium, the in situ, electrocatalytic produced syngas components can be converted by an acetogenic bacterium, such as Clostridium ragsdalei, into acetate, ethanol, and 2,3-butanediol. In order to study the simultaneous conversion of CO, CO2, and formate together with H2 with C. ragsdalei, fed-batch processes were conducted with continuous gassing using a fully controlled stirred tank bioreactor. Formate was added continuously, and various initial CO partial pressures (pCO0) were applied. C. ragsdalei utilized CO as the favored substrate for growth and product formation, but below a partial pressure of 30 mbar CO in the bioreactor, a simultaneous CO2/H2 conversion was observed. Formate supplementation enabled 20–50% higher growth rates independent of the partial pressure of CO and improved the acetate and 2,3-butanediol production. Finally, the reaction conditions were identified, allowing the parallel CO, CO2, formate, and H2 consumption with C. ragsdalei at a limiting CO partial pressure below 30 mbar, pH 5.5, n = 1200 min−1, and T = 32 °C. Thus, improved carbon and electron conversion is possible to establish efficient and sustainable processes with acetogenic bacteria, as shown in the example of C. ragsdalei.
A Study on Assessment of Rural Health Care System in India: Schemes and Implications
Authors: Suresh Kumar J , Shobana D 
Published: June 2024

India’s rural healthcare system plays a pivotal role in ensuring access to quality healthcare for a significant portion of the population. This study aims to shed light on the state of rural healthcare infrastructure, the effectiveness of government healthcare initiatives, and the far-reaching implications for rural communities. Rural India presents unique healthcare challenges characterized by disparities in healthcare infrastructure, limited access to medical services, and varying health outcomes. The government of India has launched several healthcare schemes and initiatives over the years, such as the National Rural Health Mission (NRHM) and Ayushman Bharat, to address these challenges. Understanding the impact of these schemes and their consequences is essential to inform future healthcare strategies and policies. This study provides a holistic view of the primary healthcare infrastructure in rural India, offering insights into the effectiveness of government schemes and their implications for the health and well-being of rural populations. Its findings serve as a valuable resource for policymakers, stakeholders, and healthcare professionals working toward the improvement of rural healthcare in India.
The era of the “golden workers” and the collective bargaining challenges for the age management in companies
Authors: Serrano Argüeso Mariola 
Published: June 2024

The ageing of the population is a fact, and also a worldwide social concern. There are two underlying problems in the business world that must be connected: On one hand, the need for older people to remain in the labour market and, on the other hand, the prejudices that exist in the business world in relation to older people. The plans known as generational diversity plans are essential for keeping older people in the labour market but, taking into account previous experiences, these plans should be developed in the field of the collective bargaining, preferably in a mandatory manner, which is not currently the case.
«ПРОСВІТЯНСЬКІ ХАТИ» НА ВОЛИНІ: ОСОБЛИВОСТІ ВИНИКНЕННЯ І ДІЯЛЬНОСТІ (1931-1939 РР.)
Authors: Давидюк Руслана 
Published: June 2024

У статті висвітлено обставини появи, форми діяльності та особливості співпраці з польською владою української культурно-освітньої організації «Просвітянська хата», осередки якої діяли з 1931 до 1939 р. по селах Волинського воєводства. Доведено, що «Просвітянські хати» репрезентували проурядові культурно-освітні практики українців у Західній Волині. Методологія дослідження базується на хронологічному, історико-культурному методах, а також методах аналізу і синтезу. Наукова новизна статті полягає у залучені до наукового обігу архівних документів, міжвоєнної періодики, що дозволило виокремити особливості функціонування «Просвітянських хат» як культурно-освітніх організацій при регіональній проурядовій партії Волинське українське об’єднання (ВУО). Активізація культурно-освітнього українського руху Західної Волині у 1920-х років була пов’язана з діяльністю повітових «Просвіт» та їх філій по селах. Після їх заборони у селах за сприяння польської воєводської влади почали виникати «Просвітянські хати». Основні форми їх роботи: розповсюдження українських книг, газет, підручників, відкриття бібліотек, проведення концертів, заснування драматичних гуртків, організація національних свят, а також підтримка ідей українсько-польського порозуміння. Доведено, що, незважаючи на труднощі і перешкоди, діяльність «Просвітянських хат» була важливим чинником збереження національної самосвідомості місцевих українців.
The role of organizational culture in material and non-material incentives for employees
Authors: Golubetskaya N. P. , Zamiralov D. A. , Sushkov A. V. 
Published: June 2024

Aim. To identify the role played by organizational culture in material and non-material stimulation of employees.Objectives. To describe and structure the key components of organizational culture; to disclose the concept of organizational climate and identify its relationship with organizational culture; to characterize the influence of the type of corporate culture on the prevailing type of incentives.Methods. The conducted research is based on the descriptive method, analysis and comparative method. Innovative, systemic and scientific approaches were applied as basic ones.Results. In today's highly turbulent global economic space, the survival of a company serves as an essential element of its strategy. Within the framework of counteraction to destructive forces from the external environment it is the organizational culture that today acts as a staple that allows to maintain the company at the proper level. In the context of understanding the essence of organizational culture, the authors adhere to this approach. The author's definition of the concept under study is given in the article. The approach based on the position that organizational climate is a part of organizational culture is presented. The influence of the type of corporate culture on the prevailing type of incentives is estimated.Conclusions. The study of organizational culture as a process reflects the understanding that each type of it has its own peculiarity. Practically there is no strictly defined type, especially since each company creates an individual organizational culture. The article traces the understanding that in the formation of organizational culture should pay close attention to the role played by one or another of its type in the material and non-material stimulation of employees.
Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment
Authors: Löfvendahl Sofia , Andersson Emelie , Olofsson Sara , Wahlberg Karin , Bjermer Leif , Tornling Göran , Hjelmgren Jonas 
Published: June 2024

Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients’ preferences for attributes related to administration mode of corticosteroids in AARs. Methods: A web-based survey was sent to a sample from the adult Swedish population (≥18 years) with experience of corticosteroid treatment for AAR. We assessed the willingness to pay (WTP) for attributes related to corticosteroid treatment by applying a discrete choice experiment (DCE) approach. DCE attributes were administration mode, time to symptom relief, and price. The WTP for each attribute was derived using the attribute’s coefficient in a logistic regression analysis. We specified a forced choice (FC) and an unforced choice (UC) model. In the FC model, the respondents chose between 2 hypothetical treatments and in the UC model, between any of 2 hypothetical treatments and their current treatment. Results: The final study population included 348 subjects, of which 80% were women. All the evaluated DCE attributes were significant predictors for the treatment choice (p<.001). In the FC model, the incremental WTP for an oral film compared with tablets was 409 Swedish kronor (SEK [≈€36.7]), with no other factors considered. In the UC model, the incremental WTP for the oral film compared with tablets was 574 SEK (≈€51.7). After considering the value of the respondents’ current treatment, the WTP for the oral film decreased to 336 SEK (≈€30.3). The total WTP was reduced by 17 SEK (≈€1.5) per minute of shorter time to symptom relief. Subgroup analyses showed that people with circulatory symptoms and experience of swallowing difficulties related to allergy medication had higher WTP for the oral film than the average respondent. Conclusion: The findings show a substantial economic benefit of the oral film vs tablets for patients with AARs in Sweden. This result remained also after compensation for the full value of the patients’ current treatment.
Evaluation of Hypochlorite Concentration in Household Bleaches as Colour Removal Agent on Coloured Cotton Fabrics
Authors: Adeboye Adebiyi Oladipupo , Goriola Olajide Rahman , Falode Christopher Gabriel , Ogunduyile Sunday Roberts , Eromosele Catherine Oluyemisi 
Published: June 2024

Bleaches are known to remove stains from fabric. This study evaluates chlorine-based household bleaches as effective fabric colour removal agents and was conducted in the Chemistry and Textile laboratories of the Federal University of Agriculture, Abeokuta using experimental design. Five common household bleaches were collected from markets in study areas. The concentrations of Sodium hypochlorite in each bleach sample as indicated by the manufacturer were: A (3.85%), B (3.5%), C (not available), D (4.3%) and E (5.3%). To confirm the concentration of sodium hypochlorite in each bleach sample, Redox titration was conducted. One-minute Spot Test was used to determine the time taken for each bleach sample to remove colour (black, brown, navy blue, purple and army-green) from fabrics samples and similar test conducted with pure sodium hypochlorite (7.21% Chlorine) as control. The L*a*b* values for fabric colour change were obtained from images of the fabric samples using Fiji-Image J and Corel Photo-Paint 17. The laboratory analysis and evaluation revealed the concentration of hypochlorite in the bleaches samples as A: 0.36% (3.56 g/dm3), B: 3.5% (34.00g/dm3), C: 1.15% (11.48g/dm3), D: 4.29% (42.92g/dm3), and E: 0.06% (0.57g/dm3); therefore, established the information on bleaches B and D product package. The average time (seconds) to remove colour from fabric samples by bleach samples were A- 80.37; B- 19.60; C- 30.36; D- 20.10; E- no vivid colour change after 120.00 sec while colour change was obtained 7.00 sec by the control. Furthermore, Image J analysis and L*a*b* values show colour changes on fabric samples with Bleach B ((x ̅= 75.74) and D ((x) ̅= 61.22) most effective in colour removals. In conclusion, Chlorine base household bleaches containing above 1.0% V/v hypochlorite are suitable colour removal agents on coloured fabrics and not stain removals only. Consumers must be careful how to handle Chlorine household bleaches and coloured fabrics
الحرب النفسية عند الصليبيين ومقاومة المسلمين لها (489-648هـ/1096-1250م)
Authors: محمود وشاح غسان , عمرو أبو عمارة محمد 
Published: June 2024

تناول البحث استخدام الصليبيين للحرب النفسية أثناء غزوهم للعالم الإسلامي ومقاومة المسلمين لها حيث تم تقسيم الدراسة إلى ثلاثة مباحث رئيسة، الأول تناول الحرب النفسية الحديثة ووسائلها وطرقها وأنواعها وتناول المبحث الثاني ممارسة الصليبيين للحرب النفسية ووسائلهم ونتائج ذلك على العالم الإسلامي وأما المبحث الثالث فقد ناقش مقاومة المسلمين للحرب النفسية ووسائلهم وأثار ذلك.
Edad al Primer Parto de la Raza Holstein Friesian en el Ecuador
Authors: Carrillo Álvarez Israel , Cartuche Macas Luis , Chacón Marcheco Edilberto , Ortuño Barba Carlos , Guevara Viera Guillermo 
Published: June 2024

El objetivo de este trabajo fue determinar la edad al primer parto en vacas Holstein Friesian. Distribuidas en su mayoría en la región sierra a una altura que va hasta los 3,800 metros sobre el nivel del mar. La base de datos incluyó: identificación del animal, fecha de nacimiento, fecha de primer parto y ubicación geográfica del predio. En total se obtuvieron 94,163 registros de primer parto entre el período 1971-2019. Como criterio de inclusión se consideró todas las vacas con partos entre 22 y 34 meses primer parto. En Ecuador la edad promedio fue de 48 meses en el año 1971 con un importante descenso de 35-41 meses entre el año 1972-1975 y 30-35 meses entre los años 1976-2018 consolidándose entre 23-29 meses en el año 2019. Paralelamente se demuestra variabilidad entre las categorías alta en relación a la de baja con 15.1 días de diferencia en la región costa mientras que en la región oriente es de 15.69 días y de 13.82 días de diferencia en la región sierra. Este es el primer trabajo realizado en Ecuador, en el que se establece una reducción sostenida de la edad primer parto.
The Yarkovsky Effect on the Long-term Evolution of Binary Asteroids
Authors: Zhou 周 Wen-Han 文翰 , Vokrouhlický David , Kanamaru Masanori , Agrusa Harrison , Pravec Petr , Delbo Marco , Michel Patrick 
Published: June 2024

Abstract
We explore the Yarkovsky effect on small binary asteroids. While significant attention has been given to the binary YORP effect, the Yarkovsky effect is often overlooked. We develop an analytical model for the binary Yarkovsky effect, considering both the Yarkovsky–Schach and planetary Yarkovsky components, and verify it against thermophysical numerical simulations. We find that the Yarkovsky force could change the mutual orbit when the asteroid’s spin period is unequal to the orbital period. Our analysis predicts new evolutionary paths for binaries. For a prograde asynchronous secondary, the Yarkovsky force will migrate the satellite toward the location of the synchronous orbit on ∼100 kyr timescales, which could be faster than other synchronization processes such as YORP and tides. For retrograde secondaries, the Yarkovsky force always migrates the secondary outward, which could produce asteroid pairs with opposite spin poles. Satellites spinning faster than the Roche limit orbit period (e.g., from ∼4 hr to ∼10 hr) will migrate inward until they disrupt, reshape, or form a contact binary. We also predict a short-lived equilibrium state for asynchronous secondaries where the Yarkovsky force is balanced by tides. We provide calculations of the Yarkovsky-induced drift rate for known asynchronous binaries. If the NASA DART impact broke Dimorphos from synchronous rotation, we predict that Dimorphos’s orbit will shrink by

a

̇

∼

7

cm yr−1, which can be measured by the Hera mission. We also speculate that the Yarkovsky force may have synchronized the Dinkinesh–Selam system after a possible merger of Selam’s two lobes.
Gaia DR3 Data of Very Young Open Cluster NGC 6530: Distance and Evolutionary Stage of Selected Stars
Authors: Parthasarathy Mudumba 
Published: June 2024

Abstract
Gaia EDR3 and Gaia DR3 data of selected stars in the very young (1.5 million years old) open cluster NGC 6530 are presented. All the selected stars have very accurate Gaia DR3 distances. Most of the selected stars are very young B stars and several of them are young stellar objects. From the analysis of selected stars, the distance to NGC 6530 is found to be 1318 pc. The two very red stars VAJ 304 and 338 have little bit less proper motion than other members of the NGC 6530 and their Mv values are found to be −3.57 and −3.68 respectively. They are much brighter than K5 III RGB stars and less luminous than massive K5 red supergiants. It is likely VAJ 304 and VAJ 338 are not members of NGC 6530 they may be field K5 type AGB or post-AGB stars. Further study of these two stars is needed.
Heteropoda lebar sp. nov.: a new species from the highlands in Pahang State, Malaysia (Sparassidae, Heteropodinae) with a distinct sexual colour dimorphism
Authors: Chen Wenqin , Jäger Peter , Zhu Yang , Yu Long , Zhang He 
Published: June 2024

The genus Heteropoda Latreille, 1804, is ranked as the second within the family Sparassidae Bertkau, 1872. Up to now, sixteen species of this genus have been described from Malaysia.
A new species of this genus in the highlands of Pahang State, Malaysia is described under the name of H. lebar sp. nov.. Individuals of the new species live in primary forests on forest floor, active in the night on the leaf litter.