bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and characterization of novel polyurethane acrylates based on soy polyols
Authors: Wang Chengshuang , Chen Xiaoyu , Chen Jiangqiang , Liu Chengguo , Xie Hongfeng , Cheng Rongshi 
Published: June 2011

AbstractNovel polyurethane acrylates (PUAs) were prepared by the reaction of soy polyols with isophorone diisocyanate and hydroxyethylacrylate. FTIR results confirmed the formation of PUAs from different kinds of soy polyols. The glass transition, damping properties, thermal stabilities, and mechanical properties of PUAs were characterized by differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), and universal test machine. The morphology of PUAs was investigated by scanning electron microscope (SEM). The results of the swelling experiments showed that the crosslinking density of polyurethanes and PUAs directly correlated with the hydroxyl (OH) number of polyols. The DSC and DMA results displayed that the glass transition temperature of PUAs was higher than that of polyurethanes and increased with OH number. Furthermore, the formation of PUA networks improved the damping properties of polyurethanes. TGA results demonstrated the acrylation of polyurethanes improved its thermal stability. The initial decomposition temperature of polyurethanes and PUAs also increased with OH number. When compared with polyurethanes, the tensile strengths of PUAs were improved by 118%, 39%, and 9%, respectively, with the increase of OH number of three soy polyols. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011.
Remote laboratory of a quadruple tank process for learning in control engineering using different industrial controllers
Authors: Domínguez M. , Fuertes J. J. , Prada M. A. , Alonso S. , Morán A. 
Published: June 2011

AbstractEducation in technological disciplines requires students to be always in contact with real systems, where they can apply their theoretical knowledge. These systems tend to be expensive and the high initial investment is returned after a long time, as the resource can only be used by a limited number of students during the on‐site practical classes. The use of remote laboratories, which allow students to access the system through the Internet, optimizes resources by providing access to a larger number of users at any time. In this article, we present a remote laboratory of a quadruple‐tank industrial scale model, with real industrial equipment. The students carry out control activities on the system through the Internet as they would do in a laboratory classroom. The remote laboratory architecture is based on a three layer (physical layer–server layer–client layer) whose middle layer consists of four servers: Web Server, Proxy Server, Database Server, and Control Server. In the Control server, a link application based on OPC (Ole for Process Control) standard to select different industrial controllers which are connected to the scale model simultaneously has been implemented. Since the application is based on a standard, this structure can be expanded easily with other industrial controllers from other manufacturers. The remote laboratory is used in automatic and control subjects from different Spanish universities. Surveys conducted among the students about the use of Laboratory show that they perceive an improvement of their learning using the lab. © 2011 Wiley Periodicals, Inc. Comput Appl Eng Educ 22:375–386, 2014; View this article online at wileyonlinelibrary.com/journal/cae; DOI 10.1002/cae.10.1002/cae.20562
Chiral NHC‐Complexes with Dioxolane Backbone Heterogenized on MCM‐41. Catalytic Activity
Authors: Villaverde Gonzalo , Corma Avelino , Iglesias Marta , Sánchez Félix 
Published: June 2011

AbstractRhodium, palladium, and gold complexes of chiral (NHC)–dioxolane–amino ligands were prepared. Herein, new methods for the heterogenization of NHC‐chiral complexes on porous silica supports are demonstrated for the facile recovery and recycling of these expensive catalysts. Activity, selectivity, and recyclability were investigated and compared to that of the analogous homogeneous catalysts for asymmetric hydrogenation reactions. The compounds were characterized by using a variety of methods, including solid state cross‐polarization magic‐angle spinning (CP MAS) 13C NMR, FT‐IR spectroscopy, and elemental analysis. Heterogenized rhodium(I) and palladium(II) catalysts could be used at least four times without loss of activity or enantioselectivity. (NHC)–gold(I) complexes were easily immobilized and recycled by a treatment with benzonitrile during the washing steps between cycles. This washing maintained the activity and enantioselectivity.
Associations of human leukocyte antigen class II genotypes with human papillomavirus 18 infection and cervical intraepithelial neoplasia risk
Authors: Chuang Li‐Chung , Hu Chung‐Yi , Chen Hui‐Chi , Lin Pei‐Jung , Lee Borheng , Lin Ching‐Yu , Pan Mei‐Hung , You San‐Lin , Hsieh Chang‐Yao , Chen Chien‐Jen ,   Community‐Based Cancer Screening Program‐Human Papillomavirus Study Group
Published: June 2011

AbstractBACKGROUND:Only a small proportion of women infected with human papillomavirus type 18 (HPV18) may progress to persistent infection and cervical neoplasia. This community‐based cohort study aimed to assess associations with human leukocyte antigen (HLA) class II genotypes for natural infection of HPV18 and subsequent risk of cervical neoplasia.METHODS:Among 10,190 cytologically normal participants, 125 with HPV18 infection were identified by HPV blot kit. HPV18 viral load at study entry was examined by real‐time polymerase chain reaction; persistent infection was defined as HPV18 infection at 2 consecutive examinations.RESULTS:There was a significant association between HLA‐DRB1*0403 allele and high HPV18 viral load (>1000 copies in 50 ng of total DNA) at study entry (odds ratio [OR], 7.2; 95% confidence interval [CI], 2.0‐25.2). After adjustment for age and viral load at study entry, haplotype HLA‐DRB1*0405‐DQA1*0301‐DQB1*0302 was significantly associated with persistent HPV18 infection (OR, 13.3; 95% CI, 1.7‐105.9). HLA‐DRB1*0403 allele was also associated with a significantly increased risk of high‐grade squamous intraepithelial lesion or cancer, showing a multivariate‐adjusted hazard ratio (95% CI) of 18.1 (2.6‐128.5).CONCLUSIONS:HLA‐DRB1*0403 allele and HLA‐DRB1*0405‐DQA1*0301‐DQB1*0302 haplotype may play important roles in determination of high viral load and persistent infection of HPV18 and subsequent cervical neoplasia risk. Cancer 2012;. © 2011 American Cancer Society.
Ground‐ and Excited‐State Vibrational Coherence Dynamics in Bacteriorhodopsin Probed With Degenerate Four‐Wave‐Mixing Experiments
Authors: Kraack Jan Philip , Buckup Tiago , Hampp Norbert , Motzkus Marcus 
Published: June 2011

AbstractVibrational coherence dynamics in the all‐trans retinal chromophore in Bacteriorhodopsin (BR) are investigated by means of temporally and spectrally resolved degenerate four‐wave‐mixing experiments. The coherence dynamics depend on the excitation wavelength when BR samples are excited at different wavelengths in a spectral range between 520 nm to above 620 nm. The trends in the dynamics observed by tuning of the excitation wavelength allow an assignment of the wave packet dynamics to ground‐ and excited‐state potential energy surfaces. Specifically, the intensity of so‐called “out‐of‐plane” modes of polyene‐chain substituents increases for excitation wavelengths near 500 nm. It is shown that this is consistent with the assignment of out‐of‐plane modes to excited‐state coherence dynamics. Moreover, intense low‐frequency coherence dynamics around 200 cm−1 are observed for signal detection in two different spectral regions of excited‐state absorption. These modulations are assigned to excited‐state dynamics due to the observed dependence on the excitation wavelength. In addition, we show that generally high‐frequency modes (>1010 cm−1) originate from wave packet motion in the electronic ground state of all‐trans retinal.
The Prominent Enhancing Effect of the Cation–π Interaction on the Halogen–Hydride Halogen Bond in M1⋅⋅⋅C6H5X⋅⋅⋅HM2
Authors: Li Ran , Li Qingzhong , Cheng Jianbo , Liu Zhenbo , Li Wenzuo 
Published: June 2011

AbstractWe designed M1⋅⋅⋅C6H5X⋅⋅⋅HM2(M1=Li+, Na+; X=Cl, Br; M2=Li, Na, BeH, MgH) complexes to enhance halogen–hydride halogen bonding with a cation–π interaction. The interaction strength has been estimated mainly in terms of the binding distance and the interaction energy. The results show that halogen–hydride halogen bonding is strengthened greatly by a cation–π interaction. The interaction energy in the triads is two to six times as much as that in the dyads. The largest interaction energy is −8.31 kcal mol−1for the halogen bond in the Li+⋅⋅⋅C6H5Br⋅⋅⋅HNa complex. The nature of the cation, the halogen donor, and the metal hydride influence the nature of the halogen bond. The enhancement effect of Li+on the halogen bond is larger than that of Na+. The halogen bond in the Cl donor has a greater enhancement than that in the Br one. The metal hydride imposes its effect in the order HBeH<HMgH<HNa<HLi for the Cl complex and HBeH<HMgH<HLi<HNa for the Br complex. The large cooperative energy indicates that there is a strong interplay between the halogen–hydride halogen bonding and the cation–π interaction. Natural bond orbital and energy decomposition analyses indicate that the electrostatic interaction plays a dominate role in enhancing halogen bonding by a cation–π interaction.
Expression and function of KCNQ channels in larval zebrafish
Authors: Chege Sally W. , Hortopan Gabriela A. , T. Dinday Matthew , Baraban Scott C. 
Published: June 2011

AbstractMembers of the Kv7 family generate a subthreshold potassium current, termed M‐current, that regulates the excitability of principal central neurons. Mutations in two members of this family, Kv7.2 (KCNQ2) and Kv7.3 (KCNQ3) are associated with a neurological disorder known as benign familial neonatal convulsion (BFNC). Despite their importance in normal and pathological brain function, developmental expression and function of these channels remains relatively unexplored. Here, we examined the temporal expression of Kv7 channel subunits in zebrafish larvae using a real‐time quantitative PCR approach. Spatial expression in the larval zebrafish brain was assessed using whole‐mount in situ hybridization. The mRNA for three members of the Kv7 family (KCNQ2, 3 and 5) is reported in zebrafish between two and seven days post‐fertilization (dpf). Using electrophysiological techniques, we show that inhibitors of Kv7 channels (linopirdine and XE991) induce burst discharge activity in immature zebrafish between 3 and 7 dpf. This abnormal electrical activity is blocked by a Kv7 channel opener (retigabine) and was also shown to evoke convulsive behaviors in freely swimming zebrafish. Using morpholino oligonucleotides directed against KCNQ3, we confirmed a role for KCNQ channels in generation of electrical burst discharges. These results indicate that functional Kv7 channels are expressed in the larval zebrafish nervous system and could play a direct role in generation of seizure activity. © 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 186–198, 2012
Brain regionalization: Of signaling centers and boundaries
Authors: Cavodeassi Florencia , Houart Corinne 
Published: June 2011

AbstractOur knowledge of the general mechanisms controlling the formation of the vertebrate central nervous system has advanced tremendously in the last decade. Here, we discuss the impact of the combined use of cell manipulation, in vivo imaging and genetics in the zebrafish on recent progress in understanding how signaling processes progressively control regionalization of the central nervous system. We highlight the unresolved issues and speculate upon the fundamental role the zebrafish will continue having in answering them. © 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 218–233, 2012
Asymmetric Synthesis of Octahedral Coordination Complexes (Eur. J. Inorg. Chem. 19/2011)
Authors: Meggers Eric 
Published: June 2011

AbstractThe cover picture shows a selection of transition‐metal complexes in which tailored chiral ligands or auxiliaries control the metal‐centered configuration; the background highlights Alfred Werner's historical publication 100 years ago regarding the first experimental verification of metal‐centered chirality in octahedral metal complexes. Nowadays, highly preorganized chiral motifs in multidentate ligands, such as the 1,1′‐binaphthyl moiety of the shown bis(8‐quinolinolato)chromium(III) complex (top‐left corner) or the (bipyrrolidine)iron(III) complex shown in the bottom‐right corner, are capable of efficiently controlling the relative and absolute stereochemistry upon metal complexation. Alternatively, aromatic face‐to‐face π‐stacking can be exploited for the implementation of the metal‐centered chirality as demonstrated by the bis(iminobipyridine)iron(II) complex displayed in the bottom‐left corner. The ruthenium(II) complex on the top right is an intermediate in the auxiliary‐mediated asymmetric synthesis of (polypyridyl)ruthenium complexes. Further details are presented in the Microreview by E. Meggers on p. 2911 ff, which provides an overview of the asymmetric synthesis of octahedral metal complexes, ranging from the first experiments to the current state of the art. The structures of the metal complexes shown were created with PyMOL (DeLano Scientific LLC).
Transcranial magnetic stimulation and motor plasticity in human lateral cerebellum: Dual effect on saccadic adaptation
Authors: Panouillères Muriel , Neggers Sebastiaan F.W. , Gutteling Tjerk P. , Salemme Roméo , Stigchel Stefan van der , van der Geest Josef N. , Frens Maarten A. , Pélisson Denis 
Published: June 2011

AbstractThe cerebellum is a key area for movement control and sensory‐motor plasticity. Its medial part is considered as the exclusive cerebellar center controlling the accuracy and adaptive calibration of saccadic eye movements. However, the contribution of other zones situated in its lateral part is unknown. We addressed this question in healthy adult volunteers by using magnetic resonance imaging (MRI)‐guided transcranial magnetic stimulation (TMS). The double‐step target paradigm was used to adaptively lengthen or shorten saccades. TMS pulses over the right hemisphere of the cerebellum were delivered at 0, 30, or 60 ms after saccade detection in separate recording sessions. The effects on saccadic adaptation were assessed relative to a fourth session where TMS was applied to Vertex as a control site. First, TMS applied upon saccade detection before the adaptation phase reduced saccade accuracy. Second, TMS applied during the adaptation phase had a dual effect on saccadic plasticity: adaptation after‐effects revealed a potentiation of the adaptive lengthening and a depression of the adaptive shortening of saccades. For the first time, we demonstrate that TMS on lateral cerebellum can influence plasticity mechanisms underlying motor performance. These findings also provide the first evidence that the human cerebellar hemispheres are involved in the control of saccade accuracy and in saccadic adaptation, with possibly different neuronal populations concerned in adaptive lengthening and shortening. Overall, these results require a reappraisal of current models of cerebellar contribution to oculomotor plasticity. Hum Brain Mapp, 2011. © 2011 Wiley‐Liss, Inc.
Medial temporal contributions to successful face‐name learning
Authors: Westerberg Carmen E. , Voss Joel L. , Reber Paul J. , Paller Ken A. 
Published: June 2011

AbstractThe brain mechanisms that enable us to form durable associations between different types of information are not completely understood. Although the hippocampus is widely thought to play a substantial role in forming associations, the role of surrounding cortical regions in the medial temporal lobe, including perirhinal and parahippocampal cortex, is controversial. Using anatomically constrained functional magnetic resonance imaging, we assessed medial temporal contributions to learning arbitrary associations between faces and names. By sorting learning trials based on subsequent performance in associative and item‐specific memory tests, we characterized brain activity associated with successful face‐name associative learning. We found that right hippocampal activity was greater when corresponding face‐name associations were subsequently remembered than when only a face or a name, but not both, were remembered, or when single‐item information or associative information was not remembered. Neither perirhinal nor parahippocampal cortex encoding activity differed across these same conditions. Furthermore, right hippocampal activity during successful face‐name association learning was strongly correlated with activity in cortical regions involved in multimodal integration, supporting the idea that interactions between the hippocampus and neocortex contribute to associative memory. These results specifically implicate the hippocampus in associative memory formation, in keeping with theoretical formulations in which contributions to across‐domain binding differ among brain structures in the medial temporal region. Hum Brain Mapp 33:1717–1726, 2012. © 2011 Wiley Periodicals, Inc.
Merkel cell carcinoma of the head and neck
Authors: Pellitteri Phillip K. , Takes Robert P. , Lewis James S. , Devaney Kenneth O. , Harlor Evan J. , Strojan Primož , Rodrigo Juan P. , Suárez Carlos , Rinaldo Alessandra , Medina Jesus E. , Woolgar Julia A. , Ferlito Alfio 
Published: June 2011

AbstractMerkel cell carcinomas are uncommon, but aggressive, cutaneous malignancies of neuroendocrine differentiation. To the pathologist, these lesions appear as sheets of undifferentiated tumor cells with little cytoplasm and dense nuclear chromatin. They are members of the group of “small round blue cell tumors,” which includes small cell carcinomas of the lung, lymphomas, and neuroblastomas. Analogous to other skin malignancies, Merkel cell carcinomas frequently arise in the head and neck region and are commonly found in the elderly population. Merkel cell carcinomas have a high propensity for regional and distant metastases, and recurrences are frequently seen. Surgical excision is the recommended first‐line treatment followed by adjuvant radiation therapy. Because of the high incidence of occult regional metastasis, patients with clinical and radioghaphically negative necks should undergo elective dissection, irradiation, or preferably sentinel lymph node biopsy. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
Neck ultrasonography for the evaluation of the etiology of adult unilateral vocal fold paralysis
Authors: Wang Cheng‐Ping , Chen Tseng‐Cheng , Lou Pei‐Jen , Yang Tsung‐Lin , Hu Ya‐Ling , Shieh Ming‐Jium , Ko Jenq‐Yuh , Hsiao Tzu‐Yu 
Published: June 2011

AbstractBackgroundAn extralaryngeal neoplasm involving the vagus nerve and recurrent laryngeal nerve must be excluded when adult unilateral vocal fold paralysis is diagnosed.MethodsBetween 2004 and 2009, 53 adult patients with unilateral vocal fold paralysis received neck ultrasonography. Patients with laryngeal/hypopharyngeal cancer or with previously known cancers of the head and neck, thyroid, esophagus or lung, or with known etiology or trauma were excluded from this study.ResultsWe included 26 men and 27 women. Ultrasonography revealed 16 patients (30%) having subclinical tumors, including thyroid papillary carcinoma in 7 patients, vagus nerve schwannoma in 2 patients, nodular goiter in 2 patients, malignant nodes in the lower neck in 4 patients, which were metastasized from lung cancer in 3 patients, esophageal cancer in 1 patient, and cervical esophageal cancer in 1 patient.ConclusionNeck ultrasonography is useful to detect subclinical neoplasia, causing unilateral vocal fold paralysis. Thyroid cancer is the most common neoplastic etiology of adult unilateral vocal fold paralysis. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
Relationship of protein and calorie intake to the severity of oral mucositis in patients with head and neck cancer receiving radiation therapy
Authors: Zahn Karen L. , Wong Gene , Bedrick Edward J. , Poston Deborah G. , Schroeder Thomas M. , Bauman Julie E. 
Published: June 2011

AbstractBackgroundThe purpose of this study was to evaluate the relationship of calorie and protein intake to the severity of oral mucositis in patients with head and neck cancer receiving radiation therapy.MethodsPatients with head and neck cancer undergoing ≥60 Gy of radiation were eligible. Weekly data were collected for oral mucositis grade and protein and calorie intake. Proportional odds models examined the association of oral mucositis severity with nutritional predictors.ResultsDuring a 24‐month period, 40 evaluable patients met criteria for inclusion. In a multivariate backward selection model, the sole significant nutritional predictor of reduced oral mucositis severity was meeting the protein goal for the current week (p = .01; adjusted odds ratio [OR], 2.30).ConclusionPatients who met protein‐related goals during radiotherapy for head and neck cancer had less severe oral mucositis. Nutritional counseling during radiotherapy, with emphasis on protein goals, may reduce oral mucositis severity. © 2011 Wiley Periodicals, Inc. Head Neck, 2012
Measures of infant behavioral and physiological state regulation predict 54‐month behavior problems
Authors: Dale Lourdes P. , O'Hara Emily A. , Schein Rachel , Inserra Lorinn , Keen Julie , Flores Marci , Porges Stephen W. 
Published: June 2011

AbstractThis study investigated whether measures of infant temperament, regulatory disorders, and physiological reactivity and concurrent measures of family environment were predictors of child behavior problems at 54 months of age. The sample consisted of 23 children–mother dyads. The sample recruitment strategy emphasized testing both typical and fussy/difficult infants at 9 months of age. Children were categorized into low and high behavioral problem groups at 54 months of age. The children in the high behavioral problem group were more likely at 9 months to have been temperamentally difficult, to have been classified as regulatory disordered, and to have displayed respiratory sinus arrhythmia (RSA) regulation difficulties. These children also were more likely to come from families described as less cohesive and providing less focus on active/recreational activities when the children were 54 months old. A logistic regression analysis, including only the 9‐month infant measures (i.e., difficultness, regulatory disorders classification, and RSA regulation), resulted in a significant model with 100.0% accurate classification into high or low behavioral problem groups. Data suggest that infant measures of behavioral and physiological state regulation may be early indicators of child behavior problems, especially internalizing problems.
Imparting negative news to salespeople
Authors: Dubinsky Alan J. , Kim Juyoung , Lee Sanghyun 
Published: June 2011

AbstractSales managers often are required to give negative information to their sales personnel. Perhaps the salespeople's territories will be reduced, their compensation or expense program decreased, or their positions realigned or eliminated. Although extensive research has examined delivering negative news to sales personnel, no empirical work has yet explored how that inimical information should be disseminated to sales subordinates. Scholars in organizational psychology argue that providing adverse news to employees using interpersonal sensitivity is advantageous for both the individual and the organization. To date, though, this issue has not been investigated in a selling context. Therefore, this article reports the results of an exploratory study that investigated factors that influence whether sales managers provide negative communication to salespeople in an interpersonally sensitive fashion. © 2011 Wiley Periodicals, Inc.