bluuebunny/crossref_metadata_2025_split huggingface dataset:
Holography of broken U(1) symmetry
Authors: Chaffey Ian , Fichet Sylvain , Tanedo Philip 
Published: May 2024

AbstractWe examine the Abelian Higgs model in (d+ 1)-dimensional anti-de Sitter space with an ultraviolet brane. The gauge symmetry is broken by a bulk Higgs vacuum expectation value triggered on the brane. We propose two separate Goldstone boson equivalence theorems for the boundary and bulk degrees of freedom. We compute the holographic self-energy of the gauge field and show that its spectrum is either a continuum, gapped continuum, or a discretuum as a function of the Higgs bulk mass. When the Higgs has no bulk mass, the AdS isometries are unbroken. We find in that case that the dual CFT has a non-conserved U(1) current whose anomalous dimension is proportional to the square of the Higgs vacuum expectation value. When the Higgs background weakly breaks the AdS isometries, we present an adapted WKB method to solve the gauge field equations. We show that the U(1) current dimension runs logarithmically with the energy scale in accordance with a nearly-marginal U(1)-breaking deformation of the CFT.
Variation in care and outcome for fragile hip fracture patients: a European multicentre study benchmarking fulfilment of established quality indicators
Authors: Coeckelberghs E , Vanhaecht K , Akiki A , Castillón P , Cox B , Attal R El , Foss NB , Frihagen F , Gerich TG , Kanakaris NK , Kristensen MT , Mohaddes M , Panella M , Pape HC , Sermon A , Seys D , Nijs S 
Published: May 2024

Abstract
Purpose
Despite the availability of clinical guidelines for hip fracture patients, adherence to these guidelines is challenging, potentially resulting in suboptimal patient care. The goal of this study was (1) to evaluate and benchmark the adherence to recently established quality indicators (QIs), and (2) to study clinical outcomes, in fragile hip fracture patients from different European countries.

Methods
This observational, cross-sectional multicenter study was performed in 10 hospitals from 9 European countries including data of 298 consecutive patients.

Results
A large variation both within and between hospitals were seen regarding adherence to the individual QIs. QIs with the lowest overall adherence rates were the administration of systemic steroids (5.4%) and tranexamic acid (20.1%). Indicators with the highest adherence rates (above 95%) were pre-operative (99.3%) and post-operative haemoglobin level assessment (100%). The overall median time to surgery was 22.6 h (range 15.7–42.5 h). The median LOS was 9.0 days (range 5.0–19.0 days). The most common complications were delirium (23.2%) and postsurgical constipation (25.2%).

Conclusion
The present study shows large variation in the care for fragile patients with hip fractures indicating room for improvement. Therefore, hospitals should invest in benchmarking and knowledge-sharing. Large quality improvement initiatives with longitudinal follow up of both process and outcome indicators should be initiated.
The dynamic locking blade plate: seven-year follow-up results of 389 patients with a femoral neck fracture
Authors: Kalsbeek J. H. , Roerdink W. H. , Krijnen P. , Berende C. A.S. , Winkelhorst J. T. , van Walsum A. D. P. , Schipper I. B. 
Published: May 2024

Abstract
Purpose
This study aimed to investigate the long-term outcomes of patients with a femoral neck fracture (FNF), treated with the Dynamic Locking Blade Plate (DLBP).

Methods
Retrospective analysis of prospectively collected data of a multicentre cohort of patients with FNFs was conducted, regarding the long-term incidence of revision surgery after DLBP. Implant failure was evaluated using Kaplan-Meier and Cox regression analysis. Secondary outcomes were the indication for revision surgery, complications, time to revision surgery, rate of elective removal of the implant, potential predictors for revision surgery and mortality.

Results
Median follow-up of 389 included patients was 98 months; 20.6% underwent revision surgery; 28.8% after treatment of a displaced FNF (dFNF) and 10.0% with a undisplaced FNF (uFNF). 5.7% (n = 22) of the patients had operation related complications and 32.9% (n = 128) deceased during follow-up. Median time to revision surgery was 13 (dFNF) and 18 months (uFNF). 15.7% of the DLBPs were electively removed. In the multivariate Cox regression analysis, female gender (hazard ratio 2.1, 95% CI 1.2–3.7) and a TAD > 25 mm (hazard ratio 2.9, 95% CI 1.7-5) were significant predictors for revision surgery in patients with dFNF.

Conclusion
This study is the first long-term follow-up study on the outcome of the DLBP. The DLBP demonstrated positive long-term results in the treatment of FNF.
Is location more determining than WHO grade for long-term clinical outcome in patients with meningioma in the first two decades of life?
Authors: Hirschmann Dorian , Nasiri Danial , Entenmann Christian Joachim , Haberler Christine , Roetzer Thomas , Dorfer Christian , Millesi Matthias 
Published: May 2024

Summary

Objective
To identify factors for tumor relapse and poor outcome in patients with meningiomas in the first two decades of life.

Methods
All patients ≤ 21 years of age who underwent resection of a meningioma at the department of neurosurgery, Medical University of Vienna between 1989 and 2022 were included in this retrospective study. Clinical and radiological data were extracted from the medical records. Outcome and tumor relapse were analyzed for tumor location, histological findings and extent of resection.

Results
In this study 18 patients were included, 6 meningiomas were located in the skull base, 5 in the convexity and 7 in other locations including intraventricular and spine (2 patients each), falx, intraparenchymal and optic nerve sheath. Most frequent symptoms were seizures and cranial nerve palsy. In total 56% of the meningiomas were World Health organization (WHO) grade 1, 39% grade 2 and 5% grade 3. Gross total resection was achieved in 67%. The overall relapse rate was 61% and 50% underwent repeat surgery. All patients with convexity meningiomas became seizure free and had a favorable outcome. Relapse and clinical outcome were independent of WHO grade among the whole cohort but the outcome significantly depended on the WHO grade when patients with skull base meningiomas were analyzed as a subgroup. The relapse rate was significantly higher in cases of skull base location (100% vs. 42%, p = 0.038) and after subtotal resection (100% vs. 42%, p = 0.038). Clinical outcome was also significantly worse and the rate of complications was higher in patients with skull base meningiomas.

Conclusion
Patients with convexity meningiomas in the first two decades of life have a good outcome due to high chance of gross total resection. Patients with skull base meningioma are at high risk of relapse and poor outcome, particularly those with WHO grades 2 and 3. Subtotal resection in patients with skull base location is probably the main reason for this difference.
The acceptability of exercise prehabilitation before cancer surgery among patients, family members and health professionals: a mixed methods evaluation
Authors: Smyth Emily , Brennan Louise , Enright Rachel , Sekhon Mandeep , Dickson Jane , Hussey Juliette , Guinan Emer 
Published: May 2024

Abstract
Purpose
Exercise prehabilitation aims to increase preoperative fitness, reduce post-operative complications, and improve health-related quality of life. For prehabilitation to work, access to an effective programme which is acceptable to stakeholders is vital. The aim was to explore acceptability of exercise prehabilitation before cancer surgery among key stakeholders specifically patients, family members and healthcare providers.

Methods
A mixed-methods approach (questionnaire and semi-structured interview) underpinned by the Theoretical Framework of Acceptability was utilised. Composite acceptability score, (summation of acceptability constructs and a single-item overall acceptability construct), and median of each construct was calculated. Correlation analysis between the single-item overall acceptability and each construct was completed. Qualitative data was analysed using deductive and inductive thematic analysis.

Results
244 participants completed the questionnaire and n=31 completed interviews. Composite acceptability was comparable between groups (p=0.466). Four constructs positively correlated with overall acceptability: affective attitude (r=0.453), self-efficacy (r=0.399), ethicality (r=0.298) and intervention coherence (r=0.281). Qualitative data confirmed positive feelings, citing psychological benefits including a sense of control. Participants felt flexible prehabilitation program would be suitable for everyone, identifying barriers and facilitators to reduce burden.

Conclusion
Exercise prehabilitation is highly acceptable to key stakeholders. Despite some burden, it is a worthwhile and effective intervention. Stakeholders understand its purpose, are confident in patients’ ability to participate, and regard it is an important intervention contributing to patients’ psychological and physical wellbeing.

Implications
•Introduction should be comprehensively designed and clearly presented, providing appropriate information and opportunity for questions.
•Programmes should be patient-centred, designed to overcome barriers and address patients’ specific needs and goals.
•Service must be appropriately resourced with a clear referral-pathway.
Investigation of the 2010 rock avalanche onto the regenerated glacier Brenndalsbreen, Norway
Authors: Engen Siri H. , Gjerde Marthe , Scheiber Thomas , Seier Gernot , Elvehøy Hallgeir , Abermann Jakob , Nesje Atle , Winkler Stefan , Haualand Kristine F. , Rüther Denise C. , Maschler Alexander , Robson Benjamin A. , Yde Jacob C. 
Published: May 2024

AbstractRock avalanches onto glaciers are rare in Norway. Here, we examine a rock avalanche that spread onto the regenerated Brenndalsbreen, an outlet glacier from Jostedalsbreen ice cap. The rock avalanche is intriguing in that limited information exists with respect to the exact time of failure, location of detachment area, and preparatory and triggering processes. Based on an analysis of ice stratigraphy and photographic documentation, we assess that the event happened between mid-March and June 4, 2010. A potential triggering factor could have been heavy snow and rainfall combined with above freezing air temperatures on March 18–19, 2010. We use digital terrain models to determine that the detachment area is at an almost vertical rock slope in a narrow gorge above Lower Brenndalsbreen. The deposit volume is estimated to 0.130 ± 0.065 Mm3, and the H/L ratio and fahrböschung are 0.45 and 24°, respectively. We apply a Voellmy flow model to confirm the detachment location and volume estimate by producing realistic runout lengths. Although glacial debuttressing may have been a likely preparatory process, the detachment area was exposed for 45–70 years before the rock avalanche occurred. The supraglacial rock avalanche debris was separated into two branches with a distinct melt-out line across the glacier. The debris reached the glacier front in 2019 and 2020, where it started being deposited proglacially while Lower Brenndalsbreen kept receding. The 2010 Brenndalsbreen rock avalanche may not be a unique event, as deposits constituting evidence of an old rock avalanche are currently melting out at the glacier front.
Semi-active damping optimization of vibrational systems using the reduced basis method
Authors: Przybilla Jennifer , Pontes Duff Igor , Benner Peter 
Published: May 2024

AbstractIn this article, we consider vibrational systems with semi-active damping that are described by a second-order model. In order to minimize the influence of external inputs to the system response, we are optimizing some damping values. As minimization criterion, we evaluate the energy response, that is the $$\mathcal {H}_2$$

H
2

-norm of the corresponding transfer function of the system. Computing the energy response includes solving Lyapunov equations for different damping parameters. Hence, the minimization process leads to high computational costs if the system is of large dimension. We present two techniques that reduce the optimization problem by applying the reduced basis method to the corresponding parametric Lyapunov equations. In the first method, we determine a reduced solution space on which the Lyapunov equations and hence the resulting energy response values are computed approximately in a reasonable time. The second method includes the reduced basis method in the minimization process. To evaluate the quality of the approximations, we introduce error estimators that evaluate the error in the controllability Gramians and the energy response. Finally, we illustrate the advantages of our methods by applying them to two different examples.
Monitoring of group-structured high-dimensional processes via sparse group LASSO
Authors: Kim Sangahn , Turkoz Mehmet , Jeong Myong K. , Elsayed Elsayed A. 
Published: May 2024

AbstractIn a general high-dimensional process, a large number of process parameters or quality characteristics is found to be featured through their dependencies and relevance. The features that have similar characteristics or behaviors in the process operation can be categorized into multiple groups. Thus, when a few quality characteristics in the process change, it is highly probable that the process shift would have occurred in a few relevant groups. Recently, several advanced statistical process control techniques are developed to monitor the changes in high-dimensional processes under sparsity. However, monitoring schemes that utilize the grouped pattern of the quality characteristics are sparse. This paper proposes a new method to monitor the high-dimensional process when the grouped structure of the process data is observed. The proposed method identifies the potentially changed groups and individual variables within the groups based on a modified sparse group LASSO (MSGL) model. Then, a monitoring statistic is obtained using MSGL-based likelihood function to test abnormality of the process. Extensive numerical studies are conducted to demonstrate the effectiveness and efficiency of the proposed method. In addition, a real-life application of a liquefied natural gas process is presented to illustrate the proposed method.
A comprehensive approach to assess the seismic vulnerability of archaeological sites: the Wupatki Pueblo in Arizona
Authors: Gambilongo Laura , Chieffo Nicola , Lourenço Paulo B. 
Published: May 2024

AbstractThe proposed research work presents a comprehensive approach to assessing the seismic vulnerability of archaeological sites. This approach aims to be a quick and easy-to-use investigation procedure that enables accurate and large-scale evaluations. While the methods employed are well-established in the literature and have been widely applied to buildings, this study contributes by proposing a structured framework that integrates different assessment procedures at different levels of analysis, specifically tailored to archaeological sites. The analysis is divided into three stages within the conceptual framework: (i) the application of the Masonry Quality Index; (ii) seismic vulnerability assessment and prediction of expected damage; and (iii) analysis of individual walls’ structural response through strength domain, capacity and fragility curves. Specifically, the study explores and adapts four Vulnerability Index methods, i.e. GNDT, Formisano, Vicente and Ferreira methods, to suit the specific characteristics of archaeological sites. To this end, a simplified procedure is proposed to estimate the conventional strength in the methods’ forms. The comparison of the index-based methods is then crucial for critically evaluating the reliability of vulnerability estimations. The paper illustrates the application of this framework through a detailed case study, i.e. the archaeological site of Wupatki Pueblo in Arizona (US), demonstrating its effectiveness in evaluating the seismic risk and defining the vulnerability distribution of the site. Consequently, this approach facilitates the identification of the most sensitive areas, which necessitate further investigation, providing useful outcomes for the decision-making process concerning the conservation and protection of archaeological sites.
A Note on Modelling Bidirectional Feedback Loops in Mendelian Randomization Studies
Authors: Hwang Liang-Dar , Evans David M. 
Published: May 2024

AbstractStructural equation models (SEMs) involving feedback loops may offer advantages over standard instrumental variables estimators in terms of modelling causal effects in the presence of bidirectional relationships. In the following note, we show that in the case of a single “exposure” and “outcome” variable, modelling relationships using a SEM with a simple bidirectional linear feedback loop offers no advantage over traditional instrumental variables estimators in terms of consistency (i.e. both approaches yield consistent estimates of the causal effect, provided that causal estimates are obtained in both directions). In the case of finite samples, traditional IV estimators and SEM exhibited similar power across many of the conditions we examined, although which method performed best depended on the residual correlation between variables and the strength of the instruments. In particular, the power of SEM was insensitive to the residual correlation between variables, whereas the power of the Wald estimator/2SLS improved (deteriorated) relative to SEM as the magnitude of the residual correlation increased (decreased) assuming a positive causal effect of the exposure on the outcome. The power of SEM improved relative to the Wald estimator/2SLS as the instruments explained more residual variance in the “outcome” variable.
A non-monotone trust-region method with noisy oracles and additional sampling
Authors: Krejić Nataša , Krklec Jerinkić Nataša , Martínez Ángeles , Yousefi Mahsa 
Published: May 2024

AbstractIn this work, we introduce a novel stochastic second-order method, within the framework of a non-monotone trust-region approach, for solving the unconstrained, nonlinear, and non-convex optimization problems arising in the training of deep neural networks. The proposed algorithm makes use of subsampling strategies that yield noisy approximations of the finite sum objective function and its gradient. We introduce an adaptive sample size strategy based on inexpensive additional sampling to control the resulting approximation error. Depending on the estimated progress of the algorithm, this can yield sample size scenarios ranging from mini-batch to full sample functions. We provide convergence analysis for all possible scenarios and show that the proposed method achieves almost sure convergence under standard assumptions for the trust-region framework. We report numerical experiments showing that the proposed algorithm outperforms its state-of-the-art counterpart in deep neural network training for image classification and regression tasks while requiring a significantly smaller number of gradient evaluations.
Firm Innovation in Hazy Days: Chinese Evidence
Authors: Wan Liyang , Liu Yunxiao , Lv Kangjuan , Zhang Ning 
Published: May 2024

AbstractThis paper estimates the causal effect of air pollution on firm innovation based on a nationwide sample of Chinese manufacturing firms. Using thermal inversion as instrument variable (IV), we demonstrate that air pollution significantly hurts firm innovation performance: a 1% increase in air pollution (PM2.5) in the past year, from its mean value, amounts to a 1.5% decrease in the number of invention patents compared to the average between 1999 and 2013. We also provide the casual estimate using regression discontinuity design (RDD) by exploiting the exogenous variation in pollution level caused by China’s Huai River policy: the decrease in firms’ invention patents is approximately 2.2% in the regions north of the Huai River Line. The underlying mechanism analyses reveal that poor air quality has detrimental effects on labor productivity, firms’ human capital accumulation, and financing ability. These findings highlight the substantial costs associated with air pollution, which are greater than previously thought, as it hinders innovation, a crucial driver of long-term economic growth.
Trends in incidence and mortality of early-onset cancer in Germany between 1999 and 2019
Authors: Voeltz Dina , Baginski Kira , Hornberg Claudia , Hoyer Annika 
Published: May 2024

AbstractEvidence on the recent temporal trend in the incidence and mortality of early-onset cancer, i.e., cancer diagnosed at ages of < 50 years, in Germany is scarce. To estimate the temporal trend in the incidence and mortality of early-onset cancer in Germany between 1999 and 2019. Input data were obtained from the Centre for Cancer Registry Data (Zentrum für Krebsregisterdaten, ZfKD). The analysis comprised all ages until 50 years and all types of cancer classified by the International Classification of Diseases (ICD-10)-codes C00-C97 (excl. C44). Temporal trends were estimated using negative binomial regression, differentiated by sex and cancer type. Between 1999 and 2019 in Germany, we observed stable or slightly increasing trends (0% and 1%) in the incidence of all early-onset cancers combined (C00-C97) for men and women, respectively, and strict declines in the mortality for both, men and women (-2% and − 3%). However, the trends differ largely with respect to sex and the individual cancer types. Early-onset cancer should be closely monitored to see whether stable and decreasing trends in the incidence and mortality continue. Knowing that despite decreasing incidence, the prevalence of a disease can rise due to their interplay with mortality, we recommend to maintain precise surveillance, efforts in prevention and early detection, as well as appropriate investments into healthcare resources, research and development.
Tropical Deep Convection, Cloud Feedbacks and Climate Sensitivity
Authors: Stephens Graeme L. , Shiro Kathleen A. , Hakuba Maria Z. , Takahashi Hanii , Pilewskie Juliet A. , Andrews Timothy , Stubenrauch Claudia J. , Wu Longtao 
Published: May 2024

AbstractThis paper is concerned with how the diabatically-forced overturning circulations of the atmosphere, established by the deep convection within the tropical trough zone (TTZ), first introduced by Riehl and (Malkus) Simpson, in Contr Atmos Phys 52:287–305 (1979), fundamentally shape the distributions of tropical and subtropical cloudiness and the changes to cloudiness as Earth warms. The study first draws on an analysis of a range of observations to understand the connections between the energetics of the TTZ, convection and clouds. These observations reveal a tight coupling of the two main components of the diabatic heating, the cloud component of radiative heating, shaped mostly by high clouds formed by deep convection, and the latent heating associated with the precipitation. Interannual variability of the TTZ reveals a marked variation that connects the depth of the tropical troposphere, the depth of convection, the thickness of high clouds and the TOA radiative imbalance. The study examines connections between this convective zone and cloud changes further afield in the context of CMIP6 model experiments of climate warming. The warming realized in the CMIP6 SSP5-8.5 scenario multi-model experiments, for example, produces an enhanced Hadley circulation with increased heating in the zone of tropical deep convection and increased radiative cooling and subsidence in the subtropical regions. This impacts low cloud changes and in turn the model warming response through low cloud feedbacks. The pattern of warming produced by models, also influenced by convection in the tropical region, has a profound influence on the projected global warming.