bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-Sectional Survey of Sexual Dysfunction and Quality of Life Among Older People in Indonesia
Authors: Santosa Ailiana , Őhman Ann , Högberg Ulf , Stenlund Hans , Hakimi Mohammad , Ng Nawi 
Published: March 2011

ABSTRACT

Introduction
The burden of sexual dysfunction among older people in many low- and middle-income countries is not well known. Understanding sexual dysfunction among older people and its impact on quality of life is essential in the design of appropriate health promotion programs.

Aims
To assess levels of sexual function and their association with quality of life while controlling for different sociodemographic determinants and chronic diseases among men and women over 50 years of age in rural Indonesia.

Methods
A cross-sectional study was conducted in the Purworejo District, Central Java, Indonesia in 2007. The study involved 14,958 men and women over 50 years old. The association between sexual dysfunction and quality of life after controlling for potential confounders (e.g., sociodemographic determinants and self-reported chronic diseases) was analyzed by multivariable logistic regression.

Main Outcome Measures
Self-reported quality of life.

Results
Older men more commonly reported sexual activity, and sexual problems were more common among older women. The majority of older men and women reported their quality of life as good. Lack of sexual activity, dissatisfaction in sexual life, and presence of sexual problems were associated with poor self-reported quality of life in older men after adjustment for age, marital status, education, and history of chronic diseases. A presence of sexual problems was the only factor associated with poor self-reported quality of life in women. Being in a marital relationship might buffer the effect of sexual problems on quality of life in men and women.

Conclusion
Sexual dysfunction is associated with poor quality of life among older people in a rural Javanese setting. Therefore, promotion of sexual health should be an integral part of physical and mental health campaigns in older populations.
Impacting Factors for Recovery of Erectile Function Within 1 Year Following Robotic-Assisted Laparoscopic Radical Prostatectomy
Authors: Ko Woo Jin , Truesdale Matthew D. , Hruby Gregory W. , Landman Jaime , Badani Ketan K. 
Published: March 2011

ABSTRACT

Introduction
Neurovascular bundle preservation generally results in good postoperative sexual function after radical prostatectomy. However, erectile function (EF) after radical prostatectomy is still a significant concern. The same surgical technique often results in different EF outcomes.

Aim
We evaluated factors that correlate with recovery of EF within 1 year after robotic-assisted laparoscopic radical prostatectomy (RALP).

Methods
From January 2008 to May 2009, 145 consecutive patients underwent RALP by one surgeon. Patients were followed postoperatively at 3-month intervals and assessed for EF recovery, defined as an erection sufficient for penetrative intercourse with satisfaction. Baseline demographics, medical comorbidities, degree of nerve sparing, and perioperative and postoperative variables were recorded. Univariate and multivariate analyses were used to determine factors associated with EF recovery.

Main Outcome Measures
Postoperative sexual outcomes were attained prospectively via our erectile state questionnaire.

Results
Complete follow-up EF data were available on 89 men. Within 1-year follow-up, 56 men (62.9%) recovered EF and 33 men (37.1%) did not. In univariate logistic regression analysis, race (black), diabetes mellitus, hyperlipidemia, and clinical T2 carcinoma of the prostate were associated with diminished EF. Higher-preoperative Sexual Health Inventory for Men score and incremental nerve sparing (enhanced lateral prostatic fascia sparing) were associated with higher odds of recovering potency. In multivariate analysis, hyperlipidemia was primary comorbidity associated with diminished EF, and bilateral nerve sparing with a minimum unilateral-enhanced status was the impacting factor for EF recovery within 1 year after surgery.

Conclusions
Bilateral nerve preservation with a minimum unilateral-enhanced status is associated with improved recovery of EF, and hyperlipidemia is a significant negative predictive factor of postoperative EF recovery within 1 year following RALP. Therefore, it is important to control hyperlipidemia as well as to use the proper surgical technique in maximizing EF recovery within 1 year after radical prostatectomy.
Cardiovascular Mortality in Men with Erectile Dysfunction: Increased Risk But Not Inevitable
Authors: Chew Kew-Kim , Gibson Nicholas , Sanfilippo Frank , Stuckey Bronwyn , Bremner Alexandra 
Published: March 2011

ABSTRACT

Introduction
It is unclear whether men with erectile dysfunction (ED) ultimately die of cardiovascular (CV) causes.

Aim
This study examined the causes of death in men with ED and their risk of CV death.

Methods
Based on statutory death registrations and hospital morbidity data, the risk of CV death in men with ED in a linked-data study was assessed against the CV mortality risk in a reference male population.

Main Outcome Measures
Deaths from CV causes as proportions of all deaths. Age-specific rate, mortality rate ratio (MRR), standardized mortality rate ratio (SMRR), and adjusted hazard ratio (HR).

Results
CV mortality was 4.0%. Compared with the reference population, the risk of CV death was higher in men with ED (SMRR 2.2; 95% confidence interval [CI] 1.6, 3.0). Risk of CV mortality was higher in men with CV disease prior to ED (adjusted HR 1.7; 95% CI 1.1, 2.6) or with history of hospital admissions for CV events (adjusted HR 2.2; 95% CI 1.3, 3.8), compared with those without the respective history. MRR was significantly increased in the 40–69 years age group (MRR 4.1; 95% CI 3.2, 5.2). The median time interval between manifestation of ED and CV death was 10.0 years. A greater proportion of deaths from oncological than from CV causes (25.0% vs. 10.8%) occurred within the first 5 years of the manifestation of ED.

Conclusions
Although the risk of CV mortality is greater in men with ED, almost as many men die of oncological as of CV causes, with a higher proportion of oncological deaths occurring sooner subsequent to the first manifestation of ED.
Asthma and Risk of Erectile Dysfunction—A Nationwide Population-Based Study
Authors: Chou Kun-Ta , Huang Chin-Chou , Chen Yuh-Min , Perng Diang-Wang , Chao Heng-Sheng , Chan Wan-Leong , Leu Hsin-Bang 
Published: March 2011

ABSTRACT

Introduction
The increased prevalence of erectile dysfunction (ED) has been reported in patients with chronic obstructive pulmonary disease, and sustained systemic inflammation seems to play a central role in this linkage. Asthma is also a chronic inflammatory airway disorder, eliciting a low-grade systemic inflammation; however, the influence of asthma on ED has not been investigated.

Aim
Our study strived to explore the relationship of asthma and the subsequent development of ED using a nationwide, population-based database.

Methods
From 2000 to 2007, we identified newly diagnosed asthma cases involving male patients 18–55 years old. A control cohort without asthma, which was matched for age and comorbidities, was selected for comparison.

Main Outcome Measures
The two cohorts were followed up, and we observed the occurrence of ED by registry of ED diagnosis in the database.

Results
Of the 17,302 sampled patients (3,466 asthma patients vs. 13,836 control), 114 (0.66%) experienced ED during a mean follow-up period of 4.56 years, including 34 (0.98% of the asthma patients) from the asthma cohort and 80 (0.58%) from the control group. Subjects with asthma experienced a 1.909-fold (95% confidence interval [CI], 1.276–2.856; P =0.002) increase in incident ED, which was independent of age, the number of clinical visits for urologist, and other comorbidities. Kaplan–Meier analysis also revealed the tendency of asthma patients for ED development (log rank test, P =0.002). The risk of ED was higher in cases with more frequent clinical visits for asthma (asthma patients with clinical visits with &gt;24 times/year vs. &lt;12 times/year: hazard ratio [HR]: 4.154 [95% CI:1.392–12.396], P =0.011; clinical visits with 12–24 times/year vs. &lt;12 times/year HR: 3.534 [95% CI:1.245–10.032], P =0.018).

Conclusions
Asthma may be an independent risk factor for ED, and risk of ED probably increases in accordance with asthma severity.
SWEETNESS EQUIVALENCE OF DIFFERENT SWEETENERS IN STRAWBERRY‐FLAVORED YOGURT
Authors: REIS RONIELLI C. , MINIM VALÉRIA P.R. , BOLINI HELENA M.A. , DIAS BEATRIZ R.P. , MINIM LUIS A. , CERESINO ELAINE B. 
Published: March 2011

ABSTRACTTo successfully substitute sucrose for sweeteners, further studies must be carried out based on previous knowledge of sweetener concentration to determine the equivalent sweetness of such compounds. In this work, sweetness equivalence of strawberry‐flavored yogurt with different sweeteners and/or their combinations (aspartame, acesulfame‐K, cyclamate, saccharin, stevia and sucralose) and yogurt sweetened with 11.5% w/w sucrose was measured using the sensory magnitude estimation method. The sweetness concentrations equivalent to strawberry yogurt sweetened with 11.5% w/w sucrose in the tested sweeteners were 0.072% w/w for aspartame, 0.042% w/w for aspartame/acesulfame‐K (2:1), 0.064% w/w for cyclamate/saccharin, 0.043% w/w for cyclamate/saccharin (2:1)/stevia (1.8:1) and 0.30% w/w for sucralose. These results can promote the use of different sweetener combinations in strawberry‐flavored yogurt, specially acesulfame‐K and stevia, once they produce more pleasing in this product.PRACTICAL APPLICATIONSThis study provides some useful information, since there is no data in the literature about sweetness equivalence of sweeteners in yogurt, but only in simpler matrices such as pure water, juices, coffee and teas. The use of stevia blend presented several advantages such as increased sweetening power, demonstrating the potential of this natural sweetener. The magnitude estimation method has been successful in this study, being an important tool for development of new low‐calorie products. It may be noted that when evaluating different types of food using the same kinds of sweeteners, these promote distinct characteristics and that reflect directly on the sensory quality of the final product. Thus, such studies generate important information for the food industries working with dietetic food.
Influence of electrochemical polishing on the mechanical behaviour of nickel‐titanium rotary files
Authors: da Silva Marcio A. C. , Ponciano Gomes José Antônio da C. , Ormiga Fabiola 
Published: March 2011

AbstractThe purpose of this study was to evaluate the influence of electrochemical polishing on the cyclic fatigue, cutting efficiency and surface topography of Miltex nickel‐titanium rotary files. A group of files were submitted to electrochemical polishing. New files and polished files were tested for flexural fatigue and for cutting efficiency. Scanning electron microscopy observations of all files were carried out to compare the surface morphologies of polished and new files. The t‐test was used to compare the groups for cutting efficiency. Scanning electron microscopy analysis indicated that the polishing resulted in more regular surfaces in relation to the new files. Electropolished files attained a significantly higher number of cycles to fracture than new unpolished files. No statistical difference exists between the groups in relation to the cutting efficiency (t‐test, P < 0.05). The polished files keep their integrity for a significantly higher number of cycles to fracture than the new files, without compromising cutting efficiency.
HYDROCARBONS IN THE MIDDLE MIOCENE JERIBE FORMATION, DYALA REGION, NE IRAQ
Authors: Al‐Ameri T.K. , Zumberge J. , Markarian Z.M. 
Published: March 2011

The Lower Miocene Jeribe Formation in northern and NE Iraq is composed principally of dolomitic limestones with typical porosity in the range of 10–24% and mean permeability of 30 mD. The formation serves as a reservoir for oil and gas at the East Baghdad field, gas at Mansuriya, Khashim Ahmar, Pulkhana and Chia Surkh fields, and oil at Injana, Gillabat, Qumar and Jambur. A regional seal is provided by the anhydrites of the Lower Fars (Fat'ha) Formation.For this study, oil samples from the Jeribe Formation at Jambur oilfield, Oligocene Baba Formation at Baba Dome (Kirkuk field) and Late Cretaceous Tanuma and Khasib Formations at East Baghdad field were analysed in order to investigate their genetic relationships. Graphical presentation of the analytical results (including plots of pristane/nC17 versus phytane/nCl8, triangular plots of steranes, tricyclic terpane scatter plots, and graphs of pristanelphytane versus carbon isotope ratio) indicated that the oils belong to a single oil family and are derived from kerogen Types II and III. The oils have undergone minor biodegradation and are of high maturity. They were derived from marine organic matter deposited with carbonate‐rich source rocks in suboxic‐anoxic settings.A range of biomarker ratios and parameters including a C28/ C29 sterane ratio of 0.9, an oleanane index of 0.2 and low tricyclic terpane values indicate a Late Jurassic or Early Cretaceous age for the source rocks, and this age is consistent with palynomorph analyses. Potential source rocks are present in the Upper Jurassic – Lower Cretaceous Chia Gara Formation and the Middle Jurassic Sargelu Formation at the Jambur, Pulkhana, Qumar and Mansuriya fields; minor source rock intervals occur in the Balambo and Sarmord Formations. Hydrocarbon generation and expulsion from the Chia Gara Formation was indicated by pyrolysate organic matter, palynofacies type (A), and the maturity of Gleichenidites spores.Oil migration from the Chia Gara Formation source rocks (and minor oil migration from the Sargelu Formation) into the Jeribe Formation reservoirs took place along steeply‐dipping faults which are observed on seismic sections and which cut through the Upper Jurassic Gotnia Anhydrite seal. Migration is confirmed by the presence of asphalt residues in the Upper Cretaceous Shiranish Formation and by a high migration index (Rock Eval SI / TOC) in the Chia Gara Formation. These processes and elements together form a Jurassic/Cretaceous – Tertiary petroleum system whose top‐seal is the Lower Fars (Fat'ha) Formation anhydrite.
CONDENSATES IN THE PY30‐I STRUCTURE, PANYU UPLIFT, PEARL RIVER MOUTH BASIN, SOUTH CHINA SEA: EVIDENCE FOR HYDROTHERMAL ACTIVITY ASSOCIATED WITH PETROLEUM MIGRATION AND ACCUMULATION
Authors: Guo Xiaowen , He Sheng , Liu Keyu , Cao Feng , Shi Hesheng , Zhu Junzhang 
Published: March 2011

Condensates are present in the PY30–1 structure in the Panyu Uplift, Pearl River Mouth Basin. Biomarkers and compound‐specific stable carbon isotope ratios of three condensate and two source rock samples indicate that the condensates were generated by lacustrine mudstones and coals in the Oligocene Enping Formation with a minor contribution from mudstones in the Eocene Wenchang Formation. Elevated vitrinite reflectance values, high smectite‐illite transformation ratios, and elevated fluid inclusion homogenization temperatures (about 100®C higher than normal borehole temperatures) point to the influence of hydrothermal fluids at the PY30–1 structure. Hydrocarbon migration was found to have occurred at the same time as hydrothermal activity.Modelling of formation pressure evolution in the Wenchang and Enping Formation source rocks in the Baiyun Depression, adjacent to the south of the Panyu Uplift, suggest that there were three episodes of overpressure release at approximately 40–37 Ma, 33–31 Ma and 16–10 Ma. Overpressure release was probably induced by uplift and erosion during the Zhuqiong, Nanhai and Dongsha phases of tectonic deformation, respectively. The third episode of overpressure release coincided with the main phase of hydrocarbon migration.The accumulation of condensates at the PY30–1 structure probably followed hydrocarbon expulsion from source rocks as a result of overpressure release in the adjacent Baiyun Depression. Vertical migration into overlying reservoir rocks occurred through faults associated with a fluid diapir which is present at the core of the PY30‐I structure. The faults are pathways along which petroleum can migrate up to shallow reservoirs.
Immunogenicity and safety of pandemic influenza A (H1N1) 2009 vaccine: systematic review and meta‐analysis
Authors: Yin J. Kevin , Khandaker Gulam , Rashid Harunor , Heron Leon , Ridda Iman , Booy Robert 
Published: March 2011

Please cite this paper as: Yin et al. (2011) Immunogenicity and safety of pandemic influenza A (H1N1) 2009 vaccine: systematic review and meta‐analysis. Influenza and Other Respiratory Viruses 5(5), 299–305.The emergence of the 2009 H1N1 pandemic has highlighted the need to have immunogenicity and safety data on the new pandemic vaccines. There is already considerable heterogeneity in the types of vaccine available and of study performed around the world. A systematic review and meta‐analysis is needed to assess the immunogenicity and safety of pandemic influenza A (H1N1) 2009 vaccines. We searched Medline, EMBASE, the Cochrane Library and other online databases up to 1st October 2010 for studies in any language comparing different pandemic H1N1 vaccines, with or without placebo, in healthy populations aged at least 6 months. The primary outcome was seroprotection according to haemagglutination inhibition (HI). Safety outcomes were adverse events. Meta‐analysis was performed for the primary outcome. We identified 18 articles, 1 only on safety and 17 on immunogenicity, although 1 was a duplicate. We included 16 articles in the meta‐analysis, covering 17 921 subjects. Adequate seroprotection (≥70%) was almost invariably achieved in all age groups, and even after one dose and at low antigen content (except in children under 3 years receiving one dose of non‐adjuvanted vaccine). Non‐adjuvanted vaccine from international companies and adjuvanted vaccines containing oil in water emulsion (e.g. AS03, MF59), rather than aluminium, performed better. Two serious vaccination‐associated adverse events were reported, both of which resolved fully. No death or case of Guillain–Barré syndrome was reported. The pandemic influenza (H1N1) 2009 vaccine, with or without adjuvant, appears generally to be seroprotective after just one dose and safe among healthy populations aged ≥36 months; very young children (6–35 months) may need to receive two doses of non‐adjuvanted vaccine or one dose of AS03A/B‐adjuvanted product to achieve seroprotection.
Non‐Resolving Aspects of Acute Inflammation after Spinal Cord Injury (SCI): Indices and Resolution Plateau
Authors: Prüss Harald , Kopp Marcel A , Brommer Benedikt , Gatzemeier Nicole , Laginha Ines , Dirnagl Ulrich , Schwab Jan M 
Published: March 2011

AbstractInflammatory resolution is an active, highly regulated process already encoded at the onset of inflammation and required to prevent the transition into chronic inflammation associated with spreading of tissue injury and exacerbated scarring. We introduce objective, quantitative measurements [resolution indices (Ri) and resolution plateau (RP)] to characterize inflammatory resolution and to determine the persistence (“dwell time”) of differential leukocyte subpopulations at the lesion site after acute experimental spinal cord injury (SCI). The cell type‐specific resolution interval Ri (time between maximum cell numbers and the point when they are reduced to 50%) ranges from 1.2 days for neutrophils, 1.5 days for T lymphocytes, to 55 days for microglia/macrophages. As the resolution interval neglects exiting cell trafficking in the later period of resolution (49%–0% of lesional cells), we introduced the RP, a marker for the persisting, chronified leukocyte subsets, which are likely to participate in late degeneration and non‐resolving inflammation. Here, we identify the acute inflammatory response in central nervous system (CNS) lesions as partly non self‐limiting. Both extended resolution intervals (reduced leukocyte clearance) and elevated plateaus (permanent lesional cell numbers) provide quantitative measures to characterize residual, sustained inflammation and define cognate timeframes of impaired resolution after acute SCI.
Evaluation of three different hepatitis C virus typing methods for detection of mixed‐genotype infections
Authors: IDREES Muhammad , UR REHMAN Irshad , MANZOOR Sobia , AKBAR Haji , BUTT Sadia , AFZAL Samia , YOUSAF Muhammad Zubair , HUSSAIN Abrar 
Published: March 2011

OBJECTIVE:  To evaluate the clinical applicability of an eligible assay for the true prevalence of hepatitis C virus (HCV) mixed‐genotype infections.METHODS:  A newly developed HCV genotyping method targeting all six major HCV genotypes and 12 subtypes, restriction fragment length polymorphism (RFLP) and a serotyping assay were utilized for the detection of HCV mixed‐genotype infections using known HCV genotypes and unknown samples.RESULTS:  In a defined mix of HCV genotypes, a genotype present at levels as low as 8.3% was detected by our newly developed assay, showing a threefold increase in sensitivity over that of direct deoxyribonucleic (DNA) sequencing. A comparative study of the accuracy among the three genotyping methods was carried out on samples obtained from 50 thalassemic patients who received multiple blood transfusions. The results showed that viruses in approximately 42% of the samples from this group were determined to be infected with mixed genotypes by our newly developed method. A serotyping assay and RFLP analysis, performed with poor results, could identify only 18% and 10% of mixed‐genotype infections, respectively.CONCLUSION:  The newly developed assay may be the method of choice when detection of genotypes present at low levels in mixed‐genotype infections due to its higher level of sensitivity.
An experimental study of betadine irrigation for preventing infection during the natural orifice transluminal endoscopic surgery (NOTES) procedure
Authors: ZHENG Yong Zhi , WANG Dong , GU Jun Jun , ZHOU Miao Miao , Yu KONG Xiang , Xin DENG Shang , Ju SU Xiao , YIN Jie , GONG Yan Fang , WU Ren Pei , LI Zhao Shen 
Published: March 2011

OBJECTIVE:  To study the effect and feasibility of using betadine irrigation of the gastrointestinal tract for preventing infection during the natural orifice transluminal endoscopic surgery (NOTES) procedure.METHODS:  Twelve sows were used in this study. Four sows in the control group were lavaged with 500 mL saline. The eight sows in the experimental group were first lavaged with 500 mL saline and then irrigated with 200 mL betadine. A total of 5 mL of gastrointestinal (GI) tract fluid was collected before and after lavage, respectively, and 5 mL of peritoneal fluid was collected at the end of the NOTES procedure. A follow‐up endoscopic examination of the GI tract was performed 24 h after NOTES. The animals were killed and necropsied after 3 weeks.RESULTS:  Irrigation with betadine of the GI tract significantly reduced the bacterial load of GI fluid. One sow died of diaphragmatic injury. No inflammation, ulcer or bleeding were observed in the experimental group by endoscopy after 24 h. More adhesions and abscesses were found in the control group than in the experimental group after 3 weeks. Only one case of adhesion was observed in the experimental group using the transcolonic approach.CONCLUSIONS:  Betadine irrigation of the GI tract is effective and feasible for preventing infection during the NOTES procedure. Further studies are needed for assessing the effectiveness and safety of betadine irrigation in the clinical application of NOTES.