bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of Post‐Traumatic Headache Severity Among Deployed Military Personnel
Authors: Bryan Craig J. , Hernandez Ann M. 
Published: April 2011

(Headache2011;51:945‐953)Objective.—The current study used a cross‐sectional observational design to evaluate the relationship between psychological, physiological, and contextual factors and headache severity among 133 deployed military personnel and 4 civilian contractors diagnosed with mild traumatic brain injury (mTBI) referred to a combat support hospital in Iraq.Background.—Although TBI and headache sequelae have been documented for military combatants, little is known about factors associated with headache severity.Methods.—Military personnel (n = 157) and civilian (n = 4) contractors referred to a combat support hospital in Iraq underwent a standardized intake evaluation which included computerized neurocognitive testing, psychological and physical health questionnaires, a clinical interview, and a physical examination by a physician.Results.—Results of zero‐inflated Poisson regression modeling suggest that insomnia is associated with increased likelihood for endorsement of any headache, but loss of consciousness, post‐traumatic stress disorder symptoms, and slowed reaction time only are predictive of headache severity. Among the subset of patients presenting to the combat support hospital within 7 days of mTBI (n = 101), number of TBI symptoms demonstrated a non‐significant trend toward increased likelihood of headache endorsement of any kind, with loss of consciousness, post‐traumatic stress disorder, and slowed reaction time demonstrating significant relationships with headache severity.Conclusion.—Knowledge of predictors of post‐concussive headache onset and severity may assist clinicians in making important decisions regarding treatment recommendations for veterans with mTBI.
New guidelines for newborn resuscitation – a critical evaluation
Authors: Saugstad OD 
Published: April 2011

AbstractThe 2010 International Liaison Committee on Resuscitation guidelines for newborn resuscitation represent important progress. The criteria for assessment are simplified based on heart rate and respiration only and there is no timing of stages after the first 60 sec. Instead of giving supplemental oxygen, the guidelines state that ‘it is best to start with air’. However, the optimal oxygen concentration later in the process and for premature babies is not yet clear. A description of an adequate heart rate response is not given, and the cut‐off of 100 bpm may be arbitrary. There are still no clear recommendations regarding ventilation, inspiratory time, use of positive end expiratory pressure or continuous positive airway pressure. The guidelines do not mention which paCO2 level might be optimal. As colour pink assessment and routine suctioning of airways are not recommended anymore, there is an urgent need to obtain international consensus and create a new and revised Apgar score without these two variables.Conclusion:  In spite of improved guidelines for newborn resuscitation, there is still a number of unanswered questions and a need for more delivery room studies.
Effect of thermocycling on the flexural and impact strength of urethane‐based and high‐impact denture base resins
Authors: Machado Ana Lucia , Puckett Aaron D. , Breeding Larry C. , Wady Amanda Fucci , Vergani Carlos Eduardo 
Published: April 2011

doi: 10.1111/j.1741‐2358.2011.00474.x

Effect of thermocycling on the flexural and impact strength of urethane‐based and high‐impact denture base resinsObjective:  Mechanical properties of the acrylic resins used for denture fabrication may be influenced by water and temperature. Thus, the aim of this study was to evaluate the effect of thermocycling on the flexural and impact strength of a high‐impact (Lucitone 199) and a urethane‐based denture material (Eclipse).Materials and methods:  Flexural strength (64 × 10 × 3.3 mm) and impact strength (60 × 6 × 4 mm) specimens were made following the manufacturers’ instructions and assigned to two groups (n = 10): control (C) – not thermocycled – and T – thermocycled (5000 cycles between 5 and 55°C). Specimens were submitted to three‐point bending and Charpy impact tests.Results:  Flexural strength (MPa) and impact strength (kJ/m2) data were analysed with two‐way anova (p = 0.05). The flexural strength of material Eclipse (C, 136.5; T, 130.7) was significantly higher than that of resin Lucitone 550 (C, 99.4; T, 90.1). Material Eclipse exhibited significantly higher impact strength (C, 6.9; T, 5.3) than the resin Lucitone 550 (C, 3.5; T, 3.0). For both materials, a significant decrease in flexural and impact strengths was observed when the specimens were thermocycled.Conclusion:  Flexural and impact strengths were higher for Eclipse than for Lucitone 550, in both groups. Thermocycling decreased the flexural and impact strengths of Eclipse and Lucitone 550.
Salivary immunity in elderly individuals presented with Candida‐related denture stomatitis
Authors: Gasparoto Thaís H. , Sipert Carla R. , de Oliveira Carine E. , Porto Vinicius C. , Santos Carlos F. , Campanelli Ana P. , Lara Vanessa S. 
Published: April 2011

doi: 10.1111/j.1741‐2358.2011.00476.x

Salivary immunity in elderly individuals presented with Candida‐related denture stomatitisObjectives:  Elderly individuals with Candida‐related denture stomatitis (DS) present with a reduced defence against Candida albicans. This study evaluated levels of antimicrobial mediators in the elderly DS saliva and salivary neutrophils’ activation characteristics compared with elderly and young without DS.Methods:  Salivary peroxidases (SPO) and elastase activities (ELA), nitric oxide (NO), transforming growth factor beta (TGF‐β), IL‐6 and CCL3 production were determined in saliva from elderly with or without DS, and young control individuals. TLR4, CXCR1, CD11b, CD16 and CD32 expression on salivary neutrophils were evaluated. Correlations between number and apoptosis rate of salivary neutrophils, enzymatic activities and cytokine levels were determined.Results:  Elderly DS individuals exhibited the lowest SPO and ELA activities. Also, the activity of both enzymes was low in elderly without DS. Although both elderly groups showed higher salivary NO and TGF‐β levels compared to young control groups, elderly DS presented the highest salivary NO, TGF‐β, IL‐6 and CCL3 levels. Decreased percentages of salivary TLR4+ and CD16+ neutrophils were detected in both elderly groups. Although these damages could influence the establishment and persistence of DS, the highest levels of salivary IL‐6 and CCL3 in elderly DS could be preventing more serious complications.
Telescopic crowns: extra‐oral and intra‐oral retention force measurement –in vitro/in vivo correlation
Authors: Bayer Stefan , Stark Helmut , Gölz Lina , Keilig Ludger , Kraus Dominik , Hansen Anja , Enkling Norbert 
Published: April 2011

doi: 10.1111/j.1741‐2358.2011.00477.x

Telescopic crowns: extra‐oral and intra‐oral retention force measurement –in vitro/in vivo correlationObjective:  This study deals with the determination of the retentive forces of telescopic crowns measured extra‐ and intra‐orally and the correlation of these values.Background:  The telescopic denture is a well‐documented solution for prosthetic rehabilitation for a partially edentulous jaw. Acceptable retention forces are needed to avoid inadvertent removal of the denture during movement of the jaws. Recent literature suggests 3–7 N per attachment to be acceptable. These values are only supported by in vitro studies. In vivo data are scarce, and a correlation of the in vitro and in vivo values is lacking.Material and Methods:  Twenty‐five combined fixed‐removable prostheses with a total of 72 double crowns were used for extra‐oral retention force measurement prior to cementation (in vitro). The intra‐oral measurement was performed at 72 defined measuring points of the dentures 4–6 weeks after prosthetic rehabilitation (in vivo). A specifically designed measuring device was used.Results:  The rank correlation showed that the in vitro and in vivo values correlate with each other (Spearman’s ρ = 0.5052). Additionally, it was found that the median values measured before (1.97N) insertion of the dentures were significantly lower than after (4.70N) insertion (Mann–Whitney test, p ≤ 0.0001).Conclusion:  The retention forces measured before and after insertion of the denture correlate with each other although their dimension is significantly higher after insertion. The reason for this behaviour might be some tilting during removal. Nevertheless, the correlation allows a prediction of the clinically relevant forces by a measurement of the extra‐orally measured retentive values.
Silencing NOA1 Elevates Herbivory‐Induced Jasmonic Acid Accumulation and Compromises Most of the Carbon‐Based Defense Metabolites in Nicotiana attenuataF
Authors: Wünsche Hendrik , Baldwin Ian T. , Wu Jianqiang 
Published: April 2011

Abstract Nitric oxide‐associated protein 1 (NOA1) is involved in various abiotic stress responses and is required for plant resistance to pathogen infections. However, the role of NOA1 in plant‐herbivore interactions has not been explored. We created NOA1‐silenced Nicotiana attenuata plants (irNaNOA1). Compared with wild‐type (WT) plants, irNaNOA1 plants had highly decreased photosynthesis rates. We further examined various traits important for plant defense against its specialist herbivore Manduca sexta by treating WT and irNaNOA1 plants with mechanical wounding and M. sexta oral secretions (OS). NOA1‐silenced plants showed elevated levels of herbivory‐induced jasmonic acid (JA), but decreased JA‐isoleucine conjugate (JA‐Ile) levels. The decreased JA‐Ile levels did not result from compromised JAR (jasmonic acid resistant) activity in irNOA1 plants. Moreover, nitrogen‐rich defensive compounds, nicotine and trypsin proteinase inhibitors, did not differ between WT and irNaNOA1 plants. In contrast, concentrations of most carbon‐based defensive compounds were lower in these plants than in WT plants, although the levels of chlorogenic acid were not changed. Therefore, silencing NOA1 alters the allocation of carbon resources within the phenylpropanoid pathway. These data suggest the involvement of NOA1 in N. attenuata's defense against M. sexta attack, and highlight its role in photosynthesis, and biosynthesis of jasmonates and secondary metabolites.
Preparation of Kepler light curves for asteroseismic analyses
Authors: García R. A. , Hekker S. , Stello D. , Gutiérrez-Soto J. , Handberg R. , Huber D. , Karoff C. , Uytterhoeven K. , Appourchaux T. , Chaplin W. J. , Elsworth Y. , Mathur S. , Ballot J. , Christensen-Dalsgaard J. , Gilliland R. L. , Houdek G. , Jenkins J. M. , Kjeldsen H. , McCauliff S. , Metcalfe T. , Middour C. K. , Molenda-Zakowicz J. , Monteiro M. J. P. F. G. , Smith J. C. , Thompson M. J. 
Published: April 2011

Abstract
The Kepler mission is providing photometric data of exquisite quality for the asteroseismic study of different classes of pulsating stars. These analyses place particular demands on the pre-processing of the data, over a range of time-scales from minutes to months. Here, we describe processing procedures developed by the Kepler Asteroseismic Science Consortium to prepare light curves that are optimized for the asteroseismic study of solar-like oscillating stars in which outliers, jumps and drifts are corrected.
Temporal variability in organochlorine contamination in blood and blubber of captive Steller sea lions (Eumetopias jubatus)
Authors: Myers Matthew J. , Atkinson Shannon 
Published: April 2011

AbstractThree adult captive Steller sea lions (SSL; two females, one male) housed in Alaska were longitudinally sampled for organochlorine contaminant (OC) analysis in both blubber (n= 19) and blood (n= 69) over a 2 yr period (March 2001 to March 2003). Blood OC concentrations were similar between individuals, and exhibited significant increases in summer months (July through September) relative to winter (January through March). Additionally, paired blood and blubber sample (n= 18) OC were significantly related for all animals. The relationship of blubber OC concentrations to lipid content was significant in all animals. Although limited to a small number of animals, our study results indicate that in SSLs, blood OC were both consistent among all animals and likely changed in association with physiologically driven metabolism of blubber.
Population, density estimates, and conservation of river dolphins (IniaandSotalia) in the Amazon and Orinoco river basins
Authors: Gomez‐Salazar Catalina , Trujillo Fernando , Portocarrero‐Aya Marcela , Whitehead Hal 
Published: April 2011

AbstractThis study is part of an on‐going effort to evaluate and monitor river dolphin populations in South America. It comprises the largest initiative to estimate population size and densities ofIniaandSotaliadolphins using statistically robust and standardized methods. From May 2006 to August 2007, seven visual surveys were conducted in selected large rivers of Bolivia, Colombia, Brazil, Ecuador, Peru, and Venezuela in the Amazon and Orinoco river basins. Population sizes ofIniaandSotaliawere estimated for different habitats (main river, tributary, lake, island, confluence, and channel). A total of 291 line and 890 strip transects were conducted, covering a distance of 2,704 linear kilometers. We observed 778Inia geoffrensis, 1,323Inia boliviensis, and 764Sotalia fluviatilis. High‐density areas were identified (within 200 m from the river banks, confluences, and lakes) and we propose that these constitute critical habitat for river dolphins. High densities of river dolphins seem to coincide with well‐managed freshwater protected areas and should be considered as hot spots for river dolphins in South America.
Negotiation Offers and the Search for Agreement
Authors: Prietula Michael J. , Weingart Laurie R. 
Published: April 2011

AbstractA key component of negotiation dynamics is the search for mutually beneficial agreements, and offer exchange is a key element of that process. Rooted in the tradition of information processing psychology, we develop a theoretical model that conceives of negotiation as the collaborative search of a complexoffer space. Negotiators simplify and coordinate search via information contained inoffer exchanges, isolating subregions of the offer space for potential solutions. We suggest that early search is more exploratory and primarily influenced by thevalueof offers; later search is more focused on refinement and is influenced by thecontentof offers. In that, search by value is substantially more difficult than search by content, and parties seek value through communicating about content. Important information about the negotiators’ perspectives is revealed in comprehensive offers, and critical insight into this search process can be gained by examining the pattern of comprehensive offers.
Permanent Genetic Resources added to Molecular Ecology Resources Database 1 December 2010–31 January 2011
Authors:   Molecular Ecology Resources Primer Development Consortium, AGATA KIYOKAZU , ALASAAD SAMER , ALMEIDA‐VAL VERA MARIA FONSECA , ÁLVAREZ‐DIOS J. A. , BARBISAN F. , BEADELL JON S. , BELTRÁN J. F. , BENÍTEZ M. , BINO G. , BLEAY COLIN , BLOOR P. , BOHLMANN JÖRG , BOOTH WARREN , BOSCARI E. , CACCONE ADALGISA , CAMPOS TATIANA , CARVALHO B. M. , CLIMACO GISELE TORRES , CLOBERT JEAN , CONGIU L. , COWGER CHRISTINA , DIAS G. , DOADRIO I. , FARIAS IZENI PIRES , FERRAND N. , FREITAS PATRÍCIA D. , FUSCO G. , GALETTI PEDRO M. , GALLARDO‐ESCÁRATE CRISTIAN , GAUNT MICHAEL W. , GOMEZ OCAMPO ZANELI , GONÇALVES H. , GONZALEZ E. G. , HAYE PILAR , HONNAY O. , HYSENI CHAZ , JACQUEMYN H. , JOWERS MICHAEL J. , KAKEZAWA AKIHIRO , KAWAGUCHI ERI , KEELING CHRISTOPHER I. , KWAN YE‐SEUL , LA SPINA MICHELANGELO , LEE WAN‐OK , LEŚNIEWSKA M. , LI YANG , LIU HAIXIA , LIU XIAOLIN , LOPES S. , MARTÍNEZ P. , MEEUS S. , MURRAY BRENT W. , NUNES ALINE G. , OKEDI LOYCE M. , OUMA JOHNSON O. , PARDO B. G. , PARKS RYAN , PAULA‐SILVA MARIA NAZARÉ , PEDRAZA‐LARA C. , PERERA OMATHTHAGE P. , PINO‐QUERIDO A. , RICHARD MURIELLE , ROSSINI BRUNO C. , SAMARASEKERA N. GAYATHRI , SÁNCHEZ ANTONIO , SANCHEZ JUAN A. , SANTOS CARLOS HENRIQUE dos ANJOS , SHINOHARA WATARU , SORIGUER RAMÓN C. , SOUSA ADNA CRISTINA BARBOSA , SOUSA CAROLINA FERNANDES da SILVA , STEVENS VIRGINIE M. , TEJEDO M. , VALENZUELA‐BUSTAMANTE MYRIAM , VAN de VLIET M. S. , VANDEPITTE K. , VERA M. , WANDELER PETER , WANG WEIMIN , WON YONG‐JIN , YAMASHIRO A. , YAMASHIRO T. , ZHU CHANGCHENG 
Published: April 2011

AbstractThis article documents the addition of 238 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Alytes dickhilleni, Arapaima gigas, Austropotamobius italicus, Blumeria graminis f. sp. tritici, Cobitis lutheri, Dendroctonus ponderosae, Glossina morsitans morsitans, Haplophilus subterraneus, Kirengeshoma palmata, Lysimachia japonica, Macrolophus pygmaeus, Microtus cabrerae, Mytilus galloprovincialis, Pallisentis (Neosentis) celatus, Pulmonaria officinalis, Salminus franciscanus, Thais chocolata and Zootoca vivipara. These loci were cross‐tested on the following species: Acanthina monodon, Alytes cisternasii, Alytes maurus, Alytes muletensis, Alytes obstetricans almogavarii, Alytes obstetricans boscai, Alytes obstetricans obstetricans, Alytes obstetricans pertinax, Cambarellus montezumae, Cambarellus zempoalensis, Chorus giganteus, Cobitis tetralineata, Glossina fuscipes fuscipes, Glossina pallidipes, Lysimachia japonica var. japonica, Lysimachia japonica var. minutissima, Orconectes virilis, Pacifastacus leniusculus, Procambarus clarkii, Salminus brasiliensis and Salminus hilarii.
Why Do Homocysteine‐Lowering B Vitamin and Antioxidant E Vitamin Supplementations Appear To Be Ineffective in the Prevention of Cardiovascular Diseases?
Authors: Debreceni Balazs , Debreceni Laszlo 
Published: April 2011

SummaryHomocysteine has been established as a serious, independent risk factor for atherosclerosis. An elevated plasma homocysteine concentration is accompanied by increased cardiovascular risk; therefore, it can be assumed that lowering the plasma homocysteine level results in a decreased risk. Vitamin B complex (folic acid, and vitamins B6 and B12) substitution therapy decreases the plasma homocysteine level, inhibits oxidative stress, and ameliorates some biochemical and clinical parameters that indicate the progression of atherosclerosis. Vitamin E administration may also reduce atherogenesis through its antioxidant effect. The effectiveness of B and E vitamin substitution in decreasing cardiovascular risk has been suggested by cohort as well as prospective and retrospective studies undertaken during the last two decades. On the other hand, recent large, randomized clinical trials did not substantiate a beneficial effect of homocysteine‐lowering B vitamin supplementation or vitamin E antioxidant therapies in reducing cardiovascular risk in humans. We analyzed eight B vitamin and four E vitamin trials from a critical point of view, and in this article we reviewed and commented on their results and focused on the contradictions found in them. We showed that the possible factors implicated in the failure of vitamin therapies included inappropriate designs. The protocols neglected an essential fact: that the impact of some confounding factors, such as concomitant use of statins, acetylsalicylic acid, folic acid, and other drugs, might have led to bias and an inappropriate interpretation of the data. The cardiovascular protective and preventive effects of statins and aspirin might have reduced or abolished the possibility of observing a difference in the number of events between the vitamin and placebo groups for the clinical endpoints. We concluded that the vitamin preventive effect on cardiovascular disease may not be rejected in reference to the negative trial evidence.
Evaluation of Serum NT‐pCNP as a Diagnostic and Prognostic Biomarker for Sepsis in Dogs
Authors: DeClue A.E. , Osterbur K. , Bigio A. , Sharp C.R. 
Published: April 2011

Background: There is a need for diagnostic biomarkers that can rapidly differentiate dogs with sepsis from dogs with noninfectious forms of systemic inflammatory response syndrome (NSIRS).Objectives: To compare serum NT‐pCNP concentrations among dogs with various forms of sepsis, NSIRS, and healthy controls and to evaluate the use of serum NT‐pCNP for the diagnosis of various forms of sepsis in dogs.Animals: One hundred and twelve dogs including 63 critically ill dogs (sepsis n = 29; NSIRS n = 34) and 49 healthy control dogs.Methods: Prospective clinical investigation. Serum samples were collected for NT‐pCNP measurement from dogs with sepsis or NSIRS within 24 hours of intensive care unit admission or at the time of presentation for healthy dogs. Dogs with sepsis were subclassified based on the anatomic region of infection. Serum NT‐pCNP concentrations were compared among sepsis, NSIRS and healthy groups as well as among sepsis subgroups. The area under the curve (AUC), sensitivity, and specificity for identifying dogs with sepsis were determined.Results: Using a cut‐off value of 10.1 pmol/L, AUC, sensitivity, and specificity of NT‐pCNP for differentiating dogs with sepsis from dogs with NSIRS or healthy control dogs were 0.71 (95% CI, 0.58–0.85), 65.5% (45.7–82.1%), and 89.2% (80.4–94.9%), respectively. Serum NT‐pCNP had poor sensitivity for peritoneal sources of sepsis; AUC [0.92 (0.81–1.0)], sensitivity [94% (71–100%)], and specificity [89% (80–95%)] improved when these dogs were excluded. Serum NT‐pCNP concentration was not associated with survival in the sepsis group.Conclusions and Clinical Importance: Serum NT‐pCNP is a promising diagnostic biomarker for sepsis but is a poor indicator of septic peritonitis.
Effects of Intravenously Administered Esomeprazole Sodium on Gastric Juice pH in Adult Female Horses
Authors: Videla R. , Sommardahl C.S. , Elliott S.B. , Vasili A. , Andrews F.M. 
Published: April 2011

Background:Gastric ulcers are common in horses and treatment of horses that cannot be administered oral medication can be problematic.Objectives:To evaluate the efficacy of esomeprazole sodium administered intravenously on gastric juice pH and gastric ulcer scores in horses.Animals:Twelve adult female Quarter Horses.Methods:Esomeprazole sodium (0.5 mg/kg IV) was administered once daily to 8 horses (treatment group) and saline (5 mL IV) was administered to 4 horses (control group) for 13 consecutive days. Gastroscopy was performed and gastric juice pH and gastric ulcer score were recorded before and 1 hour after the administration of esomeprazole sodium or saline on days 1 and 5, then on day 14, 23 hours after the 13th daily dose of esomeprazole sodium or saline.Results:When compared with values before treatment, gastric juice pH was higher in esomeprazole sodium‐treated horses after treatment (4.25 ± 2.39 versus 6.43 ± 1.18;P= .002). Also, gastric juice pH was higher (P= .001) in esomeprazole sodium‐treated horses compared with saline‐treated control horses on day 5 and on day 14 values. Gastric ulcers were seen in 5/12 (43%) horses in the study.Conclusions and Clinical Importance:Esomeprazole sodium shows promise for treatment of gastric ulcers in horses with signs of dysphagia, gastric reflux, or other conditions that restrict oral intake of the current Federal Drug Administration‐approved omeprazole paste.