bluuebunny/crossref_metadata_2025_split huggingface dataset:
How visual angle influences product recommendations in response to two-sided messages
Authors: Winahjoe Sari , Paramita Widya , Jin Frances Seowon , Chiew Tung Moi , Japutra Arnold , Septianto Felix 
Published: May 2024

PurposeTwo-sided messages in advertising, which contain both negative and positive information, can have varying effects on persuasion. Thus, it is crucial to understand the conditions under which such messages are more or less effective compared to one-sided messages that only contain positive information. This research investigates the moderating role of the visual angle (close-up vs. long shot) of an image by drawing upon construal level theory.Design/methodology/approachThis research reports two experimental studies employing a 2 (message: two-sided [positive and negative information], one-sided [positive information as a control condition]) × 2 (visual angle: near [close-up], distant [long shot]) between-subjects design.FindingsThe results demonstrate that two-sided messages paired with a close-up image decrease positive electronic word of mouth (eWOM) due to increased feelings of ambivalence, while two-sided messages paired with a long-shot image increase positive eWOM due to increased perceived authenticity.Originality/valueThese findings provide insight into the impact of two-sided messages on advertising persuasion and provide guidance for marketers in developing effective communication strategies to leverage positive eWOM.
The changing health-care system in Ghana: forms of care within residential aged care facilities in urban Accra
Authors: Nyarko Joy Ato , Kwabena-Adade Joana , Kwabena-Adade Andrews 
Published: May 2024

Purpose
The emergence of residential aged care facilities (RACFs) within the Ghanaian health-care system has raised eyebrows because, hitherto, the concept of nursing homes had largely been perceived as an anomaly. The purpose of this study is to understand this emerging phenomenon and the activities of care provided within two facilities in the nation’s capital, Accra.

Design/methodology/approach
The study draws on participant observations and in-depth interviews with purposively sampled 15 residents in the two facilities and eight caregivers. The data were analysed using thematic approach.

Findings
The study found that the daily forms of care mostly performed for the elderly were intimate and non-intimate physical, medical, emotional and spiritual and end-of-life care. The bulk of activities of care were performed in the morning.

Originality/value
The study reveals that the changing landscape of health-care facilities in Ghana to include RACFs indicates RACFs have come to stay to provide different forms of care to older persons who otherwise were cared for by the family.
Development of treatment strategies by comparing the minimum inhibitory concentrations and minimum fungicidal concentrations of azole drugs in dermatophytes
Authors: Hiruma Junichiro , Nojyo Honoka , Harada Kazutoshi , Kano Rui 
Published: May 2024

AbstractWe compared the minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) of azoles in antifungal drug‐susceptible, terbinafine‐resistant, and lowly itraconazole (ITCZ)‐susceptible strains of dermatophytes. To assess the MICs of ITCZ, ravuconazole (RVCZ), efinaconazole (EFCZ), and luliconazole (LUCZ) in the isolates, broth microdilution assays were performed based on the Clinical and Laboratory Standards Institute M38‐A2 guidelines with modifications. After the assays for determining the MICs, the inoculum suspensions in wells were resuspended, then 10 μL of the growth solution in each well was inoculated onto potato dextrose agar with the use of a pipette. After 7 days of incubation at 28°C, the MFCs were determined as the lowest concentration of a drug that allowed the growth of colonies on the potato dextrose agar. The MICs in the dermatophytes were <0.03 to >32 mg/L for ITCZ, <0.03 to 4 mg/L for RVCZ, <0.03 to 2 mg/L for EFCZ, and <0.03 mg/L for LUCZ. The MFCs in the dermatophytes were 1 to >32 mg/L for ITCZ, 0.06 to >32 mg/L for RVCZ, <0.03 to 4 mg/L for EFCZ, and <0.03 to 2 mg/L for LUCZ. If the drug susceptibility test shows that the fungi are resistant to the drug, the treatment can be changed to a susceptible drug in advance, or if the fungi are low‐susceptible, the treatment can be done with the recognition that it may require a longer treatment period than usual.
Granular C3 dermatosis—A report of two cases and a mini‐review of literature
Authors: Takayama Eriko , Kuwahara Saki , Yoshioka Akiko , Tateishi Chiharu , Hashimoto Takashi 
Published: May 2024

AbstractGranular C3 dermatosis (GCD) is characterized by bullous, erythematous, and eczematous skin lesions similar to dermatitis herpetiformis, and granular deposition of complement C3 and C5b‐9 along the epidermal basement membrane zone (BMZ) by direct immunofluorescence (IF). Here, we present two cases of GCD with different clinical features. Case 1, a 49‐year‐old man, showed pruritic blisters and erythema of the extremities. Case 2, a 53‐year‐old woman, showed severely pruritic papules, erythema, and erosions on the entire body with scattered blisters, mainly on the lower extremities. Both patients showed mild eosinophilia on blood tests, subepidermal blisters and prominent eosinophilic infiltration in the upper dermis on histopathological examination, and granular BMZ deposition of C3, but not of immunoglobulins or other complement components, on direct IF. No circulating autoantibodies were detected on enzyme‐linked immunosorbent assays, chemiluminescent enzyme immunoassays, indirect IF using 1 mol/L NaCl‐split normal human skin, or immunoblotting. Diagnosis of GCD was made in both cases. Case 1 was successfully treated with topical steroids, oral minocycline, and nicotinamide without any recurrence of symptoms. Case 2 was treated with oral steroids and showed remarkable improvement, although mild pruritic papules remained. We reviewed 30 reported GCD cases, including the two cases presented here, since Hashimoto et al. first described GCD in 2016. GCD should be more widely recognized, and further accumulation and validation of cases are required.
Erythema nodosum in northern Finland between 1996 and 2019: A register‐based study
Authors: Lantto Riina , Jokelainen Jari , Huilaja Laura , Sinikumpu Suvi‐Päivikki 
Published: May 2024

AbstractErythema nodosum (EN) is seen at any age with varying and often unidentified etiology. We studied the etiology and characteristics of EN in Northern Finland. Medical records of all patients with a diagnosis code for EN between 1996 and 2019 from Oulu University Hospital were retrieved and analyzed. There were in total 142 EN cases with a female predominance (n = 112, 72.9%). The mean age of the patients was 35.9 years. There were five cases diagnosed with EN in those younger than 2 years of age. Almost one third had EN nodules in multiple anatomical locations. In addition to skin findings, systemic symptoms were common (81.0%), and seen more often in men (p < 0.05). In children and adolescents, the most common etiological factors were gastroenteritis caused by ‘Yersinia, Salmonella or Campylobacter’, followed by inflammatory bowel diseases and hormonal contraception. Bacterial infections were the most common etiological factor among adults. In 28.2% of the cases there was no identified causative factor. In this study, EN was seen surprisingly often in small children. Etiological factors varied markedly among different age groups and symptoms differed between the sexes in adults. These aspects should be taken into account when diagnosing EN patients.
Who supports the African Union? Understanding the determinants of citizens' opinion for African integration
Authors: Asongu Simplice A. , Diop Samba , Ndiaye Cheikh T. 
Published: May 2024

AbstractThe paper aims to investigate the legitimacy of the African Union by examining the socio‐demographic determinants of citizens' support of African integration. To do this, we use Rounds 4, 5, 6, and 8 of the Afrobarometer survey data corresponding to more than 110,000 respondents. Using logistics regressions, we find that individual characteristics such as living area, education, employment status, political membership, freedom, living conditions, and Living Poverty Index (LPI) are significantly related to the probability of supporting African integration. The findings are largely robust to dynamics of regional integration, the African Union, and Regional Economic Communities (RECs). Thus, since African citizens' trust in the unification could be considered a condition of legitimacy in the process, our results suggest that more efforts should be made to gain credibility, especially as it pertains to the benefits of African integration.
Tax revenue mobilization and institutional quality in sub‐Saharan Africa: An empirical investigation
Authors: Bah Mamadou 
Published: May 2024

AbstractThis paper investigates the effects of institutional quality on tax revenue collection in sub‐Saharan African countries. We include the six institutional quality indicators (i.e., voice and accountability, political stability, regulatory quality, rule of law, control of corruption, and government effectiveness) as explanatory factors for tax revenues and its components in a sample of 42 countries over the period 1996–2019. A system GMM approach was used for the estimations. Consistent with previous results, we find that institutional quality has positive and significant effects on tax revenue collection in sub‐Saharan Africa. Specifically, aggregate total tax revenues, direct taxes, income taxes, and goods and services taxes are positively affected by the six institutional quality indicators. Indirect taxes are positively associated with four indicators, with the exception of government effectiveness and political stability, while tax on international trade are affected by institutional quality factors, with the exception of control of corruption and voice and accountability. These findings indicate that sub‐Saharan African countries should improve institutional quality to boost tax revenue collection.
Systematic review and best practices for drone remote sensing of invasive plants
Authors: Singh Kunwar K. , Surasinghe Thilina D. , Frazier Amy E. 
Published: May 2024

Abstract

Drones have emerged as a cost‐effective solution to detect and map plant invasions, offering researchers and land managers flexibility in flight design, sensors and data collection schedules. A systematic review of trends in drone‐based image collection, data processing and analytical approaches is needed to advance the science of invasive species monitoring and management and improve scalability and replicability.

We systematically reviewed studies using drones for plant invasion research to identify knowledge gaps, best practices and a path toward advancing the science of invasive plant monitoring and management. We devised a database of 33 standardized reporting parameters, coded each study to those parameters, calculated descriptive statistics and synthesized how these technologies are being implemented and used.

Trends show a general increase in studies since 2009 with a bias toward temperate regions in North America and Europe. Most studies have focused on testing the validity of a machine learning or deep learning image classification technique with fewer studies focused on monitoring or modelling spread. Very few studies used drones for assessing ecosystem dynamics and impacts such as determining environmental drivers or tracking re‐emergence after disturbance. Overall, we noted a lack of standardized reporting on field survey design, flight design, drone systems, image processing and analyses, which hinders replicability and scalability of approaches. Based on these findings, we develop a standard framework for drone applications in invasive species monitoring to foster cross‐study comparability and reproducibility.

We suggest several areas for advancing the use of drones in invasive plant studies including (1) utilizing standardized reporting frameworks to facilitate scientific research practices, (2) integrating drone data with satellite imagery to scale up relationships over larger areas, (3) using drones as an alternative to in‐person ground surveys and (4) leveraging drones to assess community trait shifts tied to plant fitness and reproduction.
White matter integrity of right frontostriatal circuit predicts internet addiction severity among internet gamers
Authors: Zhou Hui , Gong Liangyu , Su Conghui , Teng Binyu , Xi Wan , Li Xiumei , Geng Fengji , Hu Yuzheng 
Published: May 2024

AbstractExcessive use of the internet, which is a typical scenario of self‐control failure, could lead to potential consequences such as anxiety, depression, and diminished academic performance. However, the underlying neuropsychological mechanisms remain poorly understood. This study aims to investigate the structural basis of self‐control and internet addiction. In a cohort of 96 internet gamers, we examined the relationships among grey matter volume and white matter integrity within the frontostriatal circuits and internet addiction severity, as well as self‐control measures. The results showed a significant and negative correlation between dACC grey matter volume and internet addiction severity (p < 0.001), but not with self‐control. Subsequent tractography from the dACC to the bilateral ventral striatum (VS) was conducted. The fractional anisotropy (FA) and radial diffusivity of dACC‐right VS pathway was negatively (p = 0.011) and positively (p = 0.020) correlated with internet addiction severity, respectively, and the FA was also positively correlated with self‐control (p = 0.036). These associations were not observed for the dACC‐left VS pathway. Further mediation analysis demonstrated a significant complete mediation effect of self‐control on the relationship between FA of the dACC‐right VS pathway and internet addiction severity. Our findings suggest that the dACC‐right VS pathway is a critical neural substrate for both internet addiction and self‐control. Deficits in this pathway may lead to impaired self‐regulation over internet usage, exacerbating the severity of internet addiction.
Levels of engagement among office‐based opioid treatment (OBOT) patients with concurrent methamphetamine use
Authors: Coules Courtney L. , Novotny Clara B. , McDonough Margaret E. , Kopak Albert M. 
Published: May 2024

AbstractBackground and ObjectivesRecent increases in methamphetamine use among people seeking treatment for opioid use disorder (OUD) has created significant demand for effective approaches to support this clinical population. This study assessed the extent to which office‐based opioid treatment (OBOT) patients, who were diagnosed with methamphetamine use disorder (MUD), engaged with providers.MethodsA retrospective analysis was conducted of adult patients (n = 470) seeking treatment for OUD who attended at least one visit between March 2020 and March 2023 at a rural regional OBOT provider. Approximately one quarter (28.7%) of patients were diagnosed with MUD in addition to receiving an OUD diagnosis. Bivariate methods and multivariate negative binomial regression models were estimated to examine the associations between clinical measures and the numbers of office visits, peer visits, and telehealth visits.ResultsRegression results indicated patients who met criteria for MUD in addition to OUD attended a higher rate of peer visits (incidence rate ratio [IRR] = 2.63, p = .036) when compared to patients who did not meet criteria for MUD. In contrast, patients with MUD and OUD diagnoses displayed significantly lower (IRR = 0.68, p < .001) engagement rates through fewer office visits relative to those who did not meet MUD criteria.Discussion and ConclusionsPatients seeking treatment for OUD who meet criteria for MUD are more likely to engage through peer support specialists rather than office visits.Scientific SignificanceThis study demonstrates the ways patients who meet criteria for OUD and MUD engage with providers to receive treatment.
Time‐dependent reduction in oxidative capacity among cultured myotubes from spinal cord injured individuals
Authors: Stevanovic Stanislava , Dalmao‐Fernandez Andrea , Mohamed Derya , Nyman Tuula A. , Kostovski Emil , Iversen Per Ole , Savikj Mladen , Nikolic Natasa , Rustan Arild C. , Thoresen G. Hege , Kase Eili T. 
Published: May 2024

AbstractBackgroundSkeletal muscle adapts in reaction to contractile activity to efficiently utilize energy substrates, primarily glucose and free fatty acids (FA). Inactivity leads to atrophy and a change in energy utilization in individuals with spinal cord injury (SCI). The present study aimed to characterize possible inactivity‐related differences in the energy metabolism between skeletal muscle cells cultured from satellite cells isolated 1‐ and 12‐months post‐SCI.MethodsTo characterize inactivity‐related disturbances in spinal cord injury, we studied skeletal muscle cells isolated from SCI subjects. Cell cultures were established from biopsy samples from musculus vastus lateralis from subjects with SCI 1 and 12 months after the injury. The myoblasts were proliferated and differentiated into myotubes before fatty acid and glucose metabolism were assessed and gene and protein expressions were measured.ResultsThe results showed that glucose uptake was increased, while oleic acid oxidation was reduced at 12 months compared to 1 month. mRNA expressions of PPARGC1α, the master regulator of mitochondrial biogenesis, and MYH2, a determinant of muscle fiber type, were significantly reduced at 12 months. Proteomic analysis showed reduced expression of several mitochondrial proteins.ConclusionIn conclusion, skeletal muscle cells isolated from immobilized subjects 12 months compared to 1 month after SCI showed reduced fatty acid metabolism and reduced expression of mitochondrial proteins, indicating an increased loss of oxidative capacity with time after injury.
A medium‐throughput approach for improved taxonomic identification of lipids preserved in ancient pottery
Authors: Drieu Léa , Lundy Jasmine , Smith Rachel K. , Bergström Ed , Talbot Helen , Primavera Milena , Fiorentino Girolamo , Craig Oliver E. , Thomas‐Oates Jane 
Published: May 2024

AbstractOrganic residue analysis (ORA) is a valuable tool for the study of ancient diets, but conventional methods remain limited in terms of taxonomic identification or to resolve mixtures. Here, we propose a method to further explore a class of compounds—triacylglycerols (TAGs)—using high‐resolution mass spectrometry to overcome these limitations in an attempt to better characterise culinary practices. Over 70 medieval Sicilian pots and a wide range of authentic fresh products were studied by matrix‐assisted laser desorption/ionisation–mass spectrometry (MALDI‐MS and MALDI‐MS/MS). MALDI‐MS analysis can distinguish fresh foodstuffs but provides little additional information regarding the contents of archaeological pottery compared to conventional ORA methods. In contrast, product ion analyses were able to deconvolute a range of animal carcass fat mixtures. In addition, detailed analysis of the composition of saturated T44 and unsaturated T50–T54 TAGs was able to provide greater taxonomic resolution regarding dairy products and plant oils.
Enhancing physicochemical, rheological properties, and in vitro rumen fermentation of starch with Melastoma candidum D. Don fruit extract
Authors: Fidriyanto Rusli , Juanssilfero Ario Betha , Sarwono Ki Ageng , Ridwan Roni , Nahrowi Nahrowi , Jayanegara Anuraga 
Published: May 2024

AbstractThe utilization of polyphenol‐modified starch in ruminants has not undergone extensive exploration. This study aimed to investigate the impact of the complex formed between starch and Melastoma candidum D. Don fruit extract on physicochemical properties, phenol release kinetics in various buffers simulating the gastrointestinal tract, methane production, and post‐rumen digestibility. The interaction between starch and M. candidum D. Don fruit extract significantly (p < 0.001) increased resistant starch and particle size diameter. The maximum phenolic release from complex between starch and M. candidum D. Don fruit extract, due to gastrointestinal tract‐simulated buffers, ranged from 22.96 to 34.60 mg/100 mg tannic acid equivalent. However, rumen and abomasum‐simulated buffers released more phenolic content, whereas the intestine‐simulated buffer showed higher antioxidant activity (ferric ion‐reducing antioxidant power). Furthermore, complex between starch and M. candidum D. Don fruit extract significantly decreased dry matter rumen digestibility (p < 0.001) and maximum methane gas production (p < 0.001).
Transgender people in clinical trials of drugs and biologics: An analysis of ClinicalTrials.gov from 2007 to 2023
Authors: Schonrock Zachary , Brackeen Sierra , Delarose Kikka E. , Tran Tiffany Q.‐D. , Cirrincione Lauren R. 
Published: May 2024

AimsTransgender people have unmet health needs related to chronic conditions such as dementia, osteoporosis and hypertension. Community‐driven advocacy increased transgender representation in phase III trials for pharmacological prevention of HIV, but the extent to which drug trials for other conditions have included transgender people is unknown. We investigated the extent to which trials of drugs and biologics represented transgender people across therapeutic areas on ClinicalTrials.gov.MethodsCross‐sectional analysis of trials of drugs and biologics registered on ClinicalTrials.gov from 2007–2023. We included efficacy and effectiveness trials (phase II–IV) with transgender‐related terms (e.g. ‘transgend*’). We labelled trials as Inclusive or Exclusive of transgender people using the trial eligibility criteria. We compared trials (therapeutic area, trial design, enrolment), summarized trials registered from 2008 onward and characterized participant enrolment for Inclusive trials with primary trial publications. We summarized continuous data using median (range), categorical data using frequencies and percentages and compared trial characteristics using Fisher's exact test.ResultsNinety‐seven trials represented transgender people. Characteristics were similar between 85 Inclusive and 12 Exclusive trials. Among Inclusive trials, 58% focused on infectious diseases (e.g. treatment or prevention of HIV and COVID‐19), 15% on mental health (e.g. post‐traumatic stress disorder, substance use‐related disorders), and the remainder focused on endocrine (9%), pain (5%), digestive system disorders (1%) and neoplasms (1%). Twenty (of 25) trials reported enrolment of transgender participants in primary trial publications or reported results.ConclusionTransgender‐inclusive trials have increased since 2008. Most trials focused on infectious diseases and mental health. Investigators should increase opportunities to include of transgender people in trials of drugs and biologics for chronic diseases.