bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experiments on Low–Cycle Ductile Damage and Failure Under Biaxial Loading Conditions
Authors: Gerke S. , Wei Z. , Brünig M. 
Published: May 2024

Abstract
Background
The damage and failure behavior of ductile metals depends on the stress state as well as on the loading history. Biaxial experiments with suitable specimens can be used to targeted generate different loading conditions, thus allowing the investigation of a wide variety of load cycles with different stress states.

Objective
In the biaxial experiments with the newly presented HC-specimen cyclic shear loads are superimposed by various constant compressive and tensile loads. Buckling during compressive loading in both axes is avoided by an additional newly introduced downholder.

Methods
The strain fields at the surfaces of the biaxial specimens are evaluated by digital image correlation (DIC), and after failure the corresponding fracture surfaces are analyzed by scanning electron microscopy (SEM). Associated numerical simulations employing the presented material model provide information on the current stress states.

Results
The introduced downholder successfully prevents buckling during compressive loading. The strain fields detect a clear influence of the shear direction and a tensile superposition of the cyclic shear load leads to more brittle and a compressive superposition to more ductile behavior. The accompanying numerical calculations reveal the associated, different stress states.

Conclusions
The new experimental program with biaxially loaded specimens for the investigation of damage and failure behavior under cyclic loading enables the targeted examination of a wide variety of load cycles and is thus suitable for the comprehensive analysis of these phenomena.
Experimental Examination of Additively Manufactured Patterns on Structural Nuclear Materials for Digital Image Correlation Strain Measurements
Authors: Novich K.A. , Phero T.L. , Cole S.E. , Greseth C.M. , McMurtrey M.D. , Estrada D. , Jaques B.J. 
Published: May 2024

Abstract
Background
There are a limited number of commercially available sensors for monitoring the deformation of materials in-situ during harsh environment applications, such as those found in the nuclear and aerospace industries. Such sensing devices, including weldable strain gauges, extensometers, and linear variable differential transformers, can be destructive to material surfaces being investigated and typically require relatively large surface areas to attach (> 10 mm in length). Digital image correlation (DIC) is a viable, non-contact alternative to in-situ strain deformation. However, it often requires implementing artificial patterns using splattering techniques, which are difficult to reproduce.

Objective
Additive manufacturing capabilities offer consistent patterns using programmable fabrication methods.

Methods
In this work, a variety of small-scale periodic patterns with different geometries were printed directly on structural nuclear materials (i.e., stainless steel and aluminum tensile specimens) using an aerosol jet printer (AJP). Unlike other additive manufacturing techniques, AJP offers the advantage of materials selection. DIC was used to track and correlate strain to alternative measurement methods during cyclic loading, and tensile tests (up to 1100 µɛ) at room temperature.

Results
The results confirmed AJP has better control of pattern parameters for small fields of view and facilitate the ability of DIC algorithms to adequately process patterns with periodicity. More specifically, the printed 100 μm spaced dot and 150 μm spaced line patterns provided accurate measurements with a maximum error of less than 2% and 4% on aluminum samples when compared to an extensometer and commercially available strain gauges.

Conclusion
Our results highlight a new pattern fabrication technique that is form factor friendly for digital image correlation in nuclear applications.
Learning to notice collaboration: examining the impact of professional development on mathematics teachers’ enhanced awareness in CSCL settings
Authors: Slakmon Benzi , Abdu Rotem 
Published: May 2024

AbstractAcknowledging the pivotal role of noticing in teachers’ professional work, it is noteworthy that its application in dialogic activities remains an area that has yet to be studied. In this study, we examine mathematics teachers’ noticing of dialogue among peers working together on problem-solving tasks and investigate the impact of a professional development intervention focused on dialogue on teachers’ noticing practices. Through think-aloud interviews, 14 teachers provided insights into their noticing practices by attending to and responding to video excerpts of dyads engaged in collaborative problem-solving in computer-supported learning environments. Their noticing practices were analyzed using a Bakhtinian-informed dialogic framework. Subsequently, the teachers participated in a professional development intervention centered around dialogue and were interviewed again using the same video excerpts. The second round of interviews was also analyzed using the same dialogic framework. The findings shed light on the initial state of teachers’ noticing and indicate a discernible improvement in their ability to notice specific dialogic attributes. These findings offer valuable insights into how collaboration and dialogue between students can be effectively supported. Additionally, the study discusses how teachers envision dialogue and considers the capacity and limitations of incorporating a dialogic vision into the noticing paradigm.
Temperature effects on adsorption and capillarity water retention mechanisms in constrained unsaturated soils
Authors: Lu Yu , McCartney John S. 
Published: May 2024

AbstractThis paper focuses on the impact of elevated temperatures on the adsorptive and capillarity water retention mechanisms of unsaturated soils under constrained (constant volume) conditions. This topic is critical for simulating the thermo-hydraulic behavior of soils in hydrogeological or geotechnical applications, including climate change effects on near surface soils, energy piles or soil borehole thermal energy storage systems in unsaturated soil layers, and buffers for geological nuclear waste repositories. A nonisothermal soil water retention curve (SWRC) that separately considers the temperature-dependency of the key parameters governing adsorptive and capillarity water retention mechanisms and soil physical parameters (e.g., surface tension, contact angle, adsorption capacity, cation exchange capacity, mean cavitation suction, air entry value and equilibrium film thickness) was developed to provide insights into the impact of temperature on water retention over the full suction range. The nonisothermal SWRC was validated using experimental data on high plasticity clays, with a good prediction of temperature effects on adsorption and capillarity water retention mechanisms in constrained unsaturated soils.
MOSS: An Open Conversational Large Language Model
Authors: Sun Tianxiang , Zhang Xiaotian , He Zhengfu , Li Peng , Cheng Qinyuan , Liu Xiangyang , Yan Hang , Shao Yunfan , Tang Qiong , Zhang Shiduo , Zhao Xingjian , Chen Ke , Zheng Yining , Zhou Zhejian , Li Ruixiao , Zhan Jun , Zhou Yunhua , Li Linyang , Yang Xiaogui , Wu Lingling , Yin Zhangyue , Huang Xuanjing , Jiang Yu-Gang , Qiu Xipeng 
Published: May 2024

AbstractConversational large language models (LLMs) such as ChatGPT and GPT-4 have recently exhibited remarkable capabilities across various domains, capturing widespread attention from the public. To facilitate this line of research, in this paper, we report the development of MOSS, an open-sourced conversational LLM that contains 16 B parameters and can perform a variety of instructions in multi-turn interactions with humans. The base model of MOSS is pre-trained on large-scale unlabeled English, Chinese, and code data. To optimize the model for dialogue, we generate 1.1 M synthetic conversations based on user prompts collected through our earlier versions of the model API. We then perform preference-aware training on preference data annotated from AI feedback. Evaluation results on real-world use cases and academic benchmarks demonstrate the effectiveness of the proposed approaches. In addition, we present an effective practice to augment MOSS with several external tools. Through the development of MOSS, we have established a complete technical roadmap for large language models from pre-training, supervised fine-tuning to alignment, verifying the feasibility of chatGPT under resource-limited conditions and providing a reference for both the academic and industrial communities. Model weights and code are publicly available at https://github.com/OpenMOSS/MOSS.
Circumferential Inferior Vena Cavectomy Without Caval Replacement in the Management of Renal Cell Carcinoma with Tumor Thrombus
Authors: Gonzalez de Gor Herrera V. , Asencio Pascual J. M. , González J. , Herranz Amo F. , LLedó García E. , Sánchez Ochoa M. A , Hernández Fernández C. 
Published: May 2024

Abstract
Purpose of Review
Renal cell carcinoma presents a unique proclivity for vascular involvement giving rise to a peculiar form of locally advanced disease so-called tumor thrombus. To date, the only curative strategy for these cases remains surgery, which should aim to remove every vestige of macroscopic disease. Most of the preexisting literature advocates opening the vena cava to allow tumor thrombus removal and subsequent venous suture closure. However, inferior vena cava circumferential resection (cavectomy) without caval replacement is possible in the majority of cases since progressive occlusion facilitates the development of a collateral venous network aimed at maintaining cardiac preload.

Recent Findings
Radical nephrectomy with tumor thrombectomy remains a surgical challenge not exempt of operative complications even in experienced hands. In opposition to what traditional cavotomy and thrombus withdrawal can offer, circumferential cavectomy without caval replacement would provide comparable or even better oncologic control, decrease the likelihood of operative bleeding, and prevent the development of perioperative pulmonary embolism.

Summary
This review focuses on the rationale of circumferential IVC resection without caval replacement and the important technical aspects of this approach in cases of renal cell carcinoma with vascular involvement. We also include an initial report on the surgical outcomes of a contemporary series of patients managed under this approach at our center.
Management of low-risk papillary thyroid cancer. Minimally-invasive treatments dictate a further paradigm shift?
Authors: Papini E. , Guglielmi R. , Novizio R. , Pontecorvi A. , Durante C. 
Published: May 2024

Abstract
Background
Current management options for PTMC include lobo-isthmectomy and active surveillance (AS). Recently, ultrasound-guided minimally invasive procedures (MITs) are offered as a nonsurgical therapy for PTMC because they do not require hospitalization and general anaesthesia, and do not result in loss of thyroid function or cosmetic damage. MITs are reported to consistently provide, mostly in large retrospective series of patients, a rapid, safe, and cost-effective way to eradicate low-risk thyroid malignancies. However, conclusive data from well-conducted prospective studies on the histologically-proven completeness of tumor ablation and the long-term clinical advantages versus AS are still lacking.

Objectives
This study aimed to evaluate the efficacy and safety of ultrasound-guided minimally invasive treatments (MITs) for PTMC in comparison to traditional surgical methods and active surveillance, and to assess their role in current clinical practice.

Methods
A structured literature review was conducted using keywords related to PTMC, MIT, and comparative techniques. Studies were evaluated based on treatment modality, patient selection, follow-up duration, complication rates, and clinical outcomes.

Results
MITs have shown promising results in the management of PTMC. These treatments offer several advantages over surgery, such as reduced use of surgical resources, lower costs, minimal work disruption, and fewer major complications. However, there are still limitations, including the need for long-term surveillance and the potential risk of incomplete tumor ablation.

Conclusions
MITs represent a promising non-surgical option for managing low-risk PTMC, especially for patients ineligible for or refusing surgery. Despite favorable outcomes, more robust prospective data are needed to confirm their long-term benefits and completeness of tumor ablation. Interdisciplinary discussions and thorough patient education on the advantages and limitations of MITs are crucial for informed decision-making.
CBX1 is involved in hepatocellular carcinoma progression and resistance to sorafenib and lenvatinib via IGF-1R/AKT/SNAIL signaling pathway
Authors: Zheng Su-Su , Wu Jing-Fang , Wu Wei-Xun , Hu Jin-Wu , Zhang Dai , Huang Cheng , Zhang Bo-Heng 
Published: May 2024

Abstract
Background
Chromobox Homolog 1 (CBX1) plays a crucial role in the pathogenesis of numerous diseases, including the evolution and advancement of diverse cancers. The role of CBX1 in pan-cancer and its mechanism in hepatocellular carcinoma (HCC), however, remains to be further investigated.

Methods
Bioinformatics approaches were harnessed to scrutinize CBX1’s expression profile, its association with tumor staging, and its potential impact on patient outcomes across various cancers. Single-cell RNA sequencing data facilitated the investigation of CBX1 expression patterns at the individual cell level. The CBX1 expression levels in HCC and adjacent non-tumor tissues were quantified through Real-Time Polymerase Chain Reaction (RT-PCR), Western Blotting (WB), and Immunohistochemical analyses. A tissue microarray was employed to explore the relationship between CBX1 levels, patient prognosis, and clinicopathological characteristics in HCC. Various in vitro assays—including CCK-8, colony formation, Transwell invasion, and scratch tests—were conducted to assess the proliferative and motility properties of HCC cells upon modulation of CBX1 expression. Moreover, the functional impact of CBX1 on HCC was further discerned through xenograft studies in nude mice.

Results
CBX1 was found to be upregulated in most cancer forms, with heightened expression correlating with adverse patient prognoses. Within the context of HCC, elevated levels of CBX1 were consistently indicative of poorer clinical outcomes. Suppression of CBX1 through knockdown methodologies markedly diminished HCC cell proliferation, invasive capabilities, migratory activity, Epithelial−mesenchymal transition (EMT) processes, and resistance to Tyrosine kinase inhibitors (TKIs). Contrastingly, CBX1 augmentation facilitated the opposite effects. Subsequent investigative efforts revealed CBX1 to be a promoter of EMT and a contributor to increased TKI resistance within HCC cells, mediated via the IGF-1R/AKT/SNAIL signaling axis. The oncogenic activities of CBX1 proved to be attenuable either by AKT pathway inhibition or by targeted silencing of IGF-1R.

Conclusions
The broad overexpression of CBX1 in pan-cancer and specifically in HCC positions it as a putative oncogenic entity. It is implicated in forwarding HCC progression and exacerbating TKI resistance through its interaction with the IGF-1R/AKT/SNAIL signaling cascade.
High MAL2 expression predicts shorter survival in women with triple-negative breast cancer
Authors: Borowczak Jędrzej , Zdrenka Marek , Socha Weronika , Gostomczyk Karol , Szczerbowski Krzysztof , Maniewski Mateusz , Andrusewicz Hanna , Łysik-Miśkurka Joanna , Nowikiewicz Tomasz , Szylberg Łukasz , Bodnar Magdalena 
Published: May 2024

Abstract
Introduction
Due to its lack of conventional surface receptors, triple-negative breast cancer (TNBC) is inherently resistant to most targeted therapies. MAL2 overexpression prompts endocytosis, conferring resistance to novel therapeutics. This study explores the role of MAL2 and PD-L1 in TNBC patients’ prognosis.

Methods
We performed immunohistochemical analysis on 111 TNBC samples collected from 76 patients and evaluated the expression of MAL2 and PD-1. We expanded the study by including The Cancer Genome Atlas (TCGA) cohort.

Results
MAL2 expression did not correlate with stage, grade, tumor size, lymph node invasion, metastasis, and PD-1 expression. Patients with high MAL2 had significantly lower 5-year survival rates (71.33% vs. 89.59%, p = 0.0224). In the tissue microarray cohort (TMA), node invasions, size, recurrence, and low MAL2 (HR 0.29 [CI 95% 0.087–0.95]; p < 0.05) predicted longer patients’ survival. In the TCGA cohort, patients with low MAL2 had significantly longer overall survival and disease-specific survival than patients with high MAL2. Older age and high MAL2 expression were the only independent predictors of shorter patient survival in the BRCA TCGA cohort.

Conclusion
High MAL2 predicts unfavorable prognosis in triple-negative breast cancer, and its expression is independent of PD-1 levels and clinicopathological features of TNBC.
The Ethical Implications of Illusionism
Authors: Frankish Keith 
Published: May 2024

AbstractIllusionism is a revisionary view of consciousness, which denies the existence of the phenomenal properties traditionally thought to render experience conscious. The view has theoretical attractions, but some think it also has objectionable ethical implications. They take illusionists to be denying the existence of consciousness itself, or at least of the thing that gives consciousness its ethical value, and thus as undermining our established ethical attitudes. This article responds to this objection. I argue that, properly understood, illusionism neither denies the existence of consciousness nor entails that consciousness does not ground ethical value. It merely offers a different account of what consciousness is and why it grounds ethical value. The article goes on to argue that the theoretical revision proposed by illusionists does have some indirect implications for our ethical attitudes but that these are wholly attractive and progressive ones. The illusionist perspective on consciousness promises to make ethical decision making easier and to extend the scope of our ethical concern. Illusionism is good news.
Bees in the city: Findings from a scoping review and recommendations for urban planning
Authors: Remmers Rutger , Frantzeskaki Niki 
Published: May 2024

AbstractOver the last decades, bee biodiversity has dropped sharply due to land use change, including urbanization. To contrast this, recent research has pointed to cities as a hotspot for bees. Because of this ambiguity, a scoping review has been conducted to examine the urban characteristics that impact bees and how bees are impacted. A total of 276 articles were analyzed against landscape and local habitat characteristics. The key findings include first that natural areas are more valuable for bees since biodiversity levels are higher. Second, urban areas generally score better than agricultural and rural areas. Third, plant biodiversity positively influences bee biodiversity. Fourth, the urban environment strongly affects some bee traits and the proportion of native bees. For making cities bee friendly and bee inclusive, we recommend to maintain natural areas, connect natural areas to urban ecosystems, encourage floral abundance and diversity and increasing the size of urban green areas overall.
Transesophageal Echocardiography in Critical Care
Authors: Bora Vaibhav , Pulijal Sri Varsha 
Published: May 2024

Abstract
Purpose of Review
In this article we describe the utility, indications, contraindications, limitations, and clinical situations in which transesophageal echocardiography (TEE) examination can be instrumental in managing patients in the intensive care unit (ICU).

Recent Findings
TEE is a safe and semi-invasive diagnostic modality that can be used to differentiate pathologies, determine hemodynamic status, guide management, and determine response to therapy. Its presence has expanded beyond the operating rooms into the critical care world. Despite limited randomized trials, evidence indicates its significant benefits and potential for early diagnosis to reduce morbidity and mortality.

Summary
Patients in the ICU present with multifactorial form of shock, hypoxemia needing monitoring and mechanical circulatory support. TEE is a low-risk diagnostic and monitoring tool which is invaluable in the ICU. Its advantages include superior visualization of cardiac structures and accurate assessment of abnormalities. Judicious utilization of TEE holds the potential to significantly influence clinical decision-making in a favorable manner.
Implications of social network structures on socially influenced decision-making
Authors: Zheng Rui , Ospina-Forero Luis , Chen Yu-wang 
Published: May 2024

AbstractIndividuals often make decisions in a social environment where social influence can impact on people’s decision-making domains such as online purchasing, political voting and voluntary vaccine uptake. Social influence can be recognised as the intentional or unintentional change in an individual’s belief, perception, or behaviours caused by an information diffusion process embedded in a social network. However, there is limited research on how this diffusion process is shaped by the topology or structure of the social network. This work provides an exploratory and systematic analysis of how decision-making outcomes in a population can be affected by both the structure of the social network and the starting node of where new information starts to diffuse. Simulation results considering three common network structures highlight how social networks with clear community structures lead to a larger absolute impact on decision-making outcomes and networks where the social connections follow a preferential attachment rule show the largest relative impact than the others. The results also suggest scenarios in which introducing new pieces of information to the social network can facilitate the information diffusion process and produce a more significant impact in terms of the overall population decision-making process.
High Strain Rate Hardening of Metallic Cellular Metamaterials
Authors: Novak N. , Vesenjak M. , Ren Z. 
Published: May 2024

AbstractStrain rate hardening caused by the changed deformation mode is a fascinating phenomenon in cellular metamaterials where the material’s stiffness and energy absorption capabilities increase as the strain rate increases. This unique behaviour is attributed to a combination of micro-inertia effects, base material’s strain rate hardening and inertia effects. At high strain rates, the metamaterial’s inertia influences its deformation response, which changes to shock mode. This work briefly presents the geometry and fabrication of different metallic metamaterials. Then, it evaluates their mechanical response at different strain rates, ranging from quasi-static to intermediate dynamic and shock, determined by experimental and computational investigation. The three deformation modes can be separated into two critical loading velocities, unique for each metamaterial, which are also presented and compared in this work for various metamaterials. The investigations show that the deformation mode change in metallic metamaterials depends on their porosity. The critical velocities separating the deformation modes decrease with increasing porosity, i.e., decreased density of the metamaterial results in reduced critical loading velocities. The shock deformation mode in cellular metamaterials is thus attainable at much lower loading velocities than in homogeneous (nonporous) materials.