bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics and risk assessment of potentially toxic elements pollution in river water and sediment in typical gold mining areas of Northwest China
Authors: Luo Yuhu , Wang Na , Liu Zhe , Sun Yingying , Lu Nan 
Published: June 2024

AbstractTo assess the concentration characteristics and ecological risks of potential toxic elements (PTEs) in water and sediment, 17 water samples and 17 sediment samples were collected in the Xiyu River to analyze the content of Cr, Ni, As, Cu, Zn, Pb, Cd and Hg, and the environmental risks of PTEs was evaluated by single-factor pollution index, Nemerow comprehensive pollution index, potential ecological risk, and human health risk assessment. The results indicated that Hg in water and Pb, Cu, Cd in sediments exceeded the corresponding environmental quality standards. In the gold mining factories distribution river section (X8-X10), there was a significant increase in PTEs in water and sediments, indicating that the arbitrary discharge of tailings during gold mining flotation is the main cause of PTEs pollution. The increase in PTEs concentration at the end of the Xiyu River may be related to the increased sedimentation rate, caused by the slowing of the riverbed, and the active chemical reactions at the estuary. The single-factor pollution index and Nemerow pollution index indicated that the river water was severely polluted by Hg. Potential ecological risk index indicated that the risk of Hg in sediments was extremely high, the risk of Cd was high, and the risk of Pb and Cu was moderate. The human health risk assessment indicated that As in water at point X10 and Hg in water at point X9 may pose non-carcinogenic risk to children through ingestion, and As at X8–X10 and Cd at X14 may pose carcinogenic risk to adults through ingestion. The average HQingestion value of Pb in sediments was 1.96, indicating that the ingestion of the sediments may poses a non-carcinogenic risk to children, As in the sediments at X8–X10 and X15–X17 may pose non-carcinogenic risk to children through ingestion.
Effect duration of lumbar sympathetic ganglion neurolysis in patients with complex regional pain syndrome: a prospective observational study
Authors: Choi Eun Joo , Kim Sunmin , Lim Dongsik , Jin Hyun Seung , Hong Sung Man , Lee Pyung Bok , Nahm Francis Sahngun 
Published: June 2024

AbstractLumbar sympathetic ganglion neurolysis (LSGN) has been used for long-term pain relief in patients with complex regional pain syndrome (CRPS). However, the actual effect duration of LSGN has not been accurately measured. This prospective observational study measured the effect duration of LSGN in CRPS patients and investigated the relationship between temperature change and pain relief. After performing LSGN, the skin temperatures of both the maximum pain site and the plantar area in the affected and unaffected limbs were measured by infrared thermography, and pain intensity was assessed before and at 2 weeks, 1 month, and 3 months. The median time to return to baseline temperature was calculated using survival analysis. The skin temperature increased significantly at all-time points relative to baseline in both regions (maximum pain site: 1.4 °C ± 1.0 °C, plantar region: 1.28 °C ± 0.8 °C, all P < 0.001). The median time to return to baseline temperature was 12 weeks (95% confidence interval [CI] 7.7–16.3) at the maximum pain site and 12 weeks (95% CI 9.4–14.6) at the plantar area. Pain intensity decreased significantly relative to baseline, at all-time points after LSGN. In conclusion, the median duration of the LSGN is estimated to be 12 weeks.
Compound heterozygous mutations in a mouse model of Leber congenital amaurosis reveal the role of CCT2 in photoreceptor maintenance
Authors: Suga Akiko , Minegishi Yuriko , Yamamoto Megumi , Ueda Koji , Iwata Takeshi 
Published: June 2024

AbstractTRiC/CCT is a chaperonin complex required for the folding of cytoplasmic proteins. Although mutations in each subunit of TRiC/CCT are associated with various human neurodegenerative diseases, their impact in mammalian models has not yet been examined. A compound heterozygous mutation in CCT2 (p.[Thr400Pro]; p.[Arg516His]) is causal for Leber congenital amaurosis. Here, we generate mice carrying each mutation and show that Arg516His (R516H) homozygosity causes photoreceptor degeneration accompanied by a significant depletion of TRiC/CCT substrate proteins in the retina. In contrast, Thr400Pro (T400P) homozygosity results in embryonic lethality, and the compound heterozygous mutant (T400P/R516H) mouse showed aberrant cone cell lamination and died 2 weeks after birth. Finally, CCDC181 is identified as a interacting protein for CCTβ protein, and its localization to photoreceptor connecting cilia is compromised in the mutant mouse. Our results demonstrate the distinct impact of each mutation in vivo and suggest a requirement for CCTβ in ciliary maintenance.
Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos
Authors: Atinbayeva Nazerke , Valent Iris , Zenk Fides , Loeser Eva , Rauer Michael , Herur Shwetha , Quarato Piergiuseppe , Pyrowolakis Giorgos , Gomez-Auli Alejandro , Mittler Gerhard , Cecere Germano , Erhardt Sylvia , Tiana Guido , Zhan Yinxiu , Iovino Nicola 
Published: June 2024

AbstractConstitutive heterochromatin is essential for transcriptional silencing and genome integrity. The establishment of constitutive heterochromatin in early embryos and its role in early fruitfly development are unknown. Lysine 9 trimethylation of histone H3 (H3K9me3) and recruitment of its epigenetic reader, heterochromatin protein 1a (HP1a), are hallmarks of constitutive heterochromatin. Here, we show that H3K9me3 is transmitted from the maternal germline to the next generation. Maternally inherited H3K9me3, and the histone methyltransferases (HMT) depositing it, are required for the organization of constitutive heterochromatin: early embryos lacking H3K9 methylation display de-condensation of pericentromeric regions, centromere-centromere de-clustering, mitotic defects, and nuclear shape irregularities, resulting in embryo lethality. Unexpectedly, quantitative CUT&Tag and 4D microscopy measurements of HP1a coupled with biophysical modeling revealed that H3K9me2/3 is largely dispensable for HP1a recruitment. Instead, the main function of H3K9me2/3 at this developmental stage is to drive HP1a clustering and subsequent heterochromatin compaction. Our results show that HP1a binding to constitutive heterochromatin in the absence of H3K9me2/3 is not sufficient to promote proper embryo development and heterochromatin formation. The loss of H3K9 HMTs and H3K9 methylation alters genome organization and hinders embryonic development.
Multi‐scale feature aggregation network for single‐image dehazing
Authors: Zhao Donghui , Mo Bo , Zhu Xiang 
Published: June 2024

AbstractTransformer possesses a broader perceptual scope, while the Convolutional Neural Network (CNN) excels at capturing local information. In this paper, the authors propose the Multi‐Sclale Feature Aggregation Network (MSFA‐Net) for single‐image dehazing which is fused with the advantages of Transformer and CNN. Our MSFA‐Net is based on the encoder–decoder structure, and there are four main innovations. Firstly, the authors make some improvements to the original Swin Transformer to make it more effective for dehazing tasks, and the authors name it Spatial Information Aggregation Transformer (SIAT). The authors place the SIAT in both encoder and decoder of MSFA‐Net for feature extraction. The authors propose an upsampling module called Efficient Spatial Resolution Recovery (ESRR) which is placed in the decoder part. Compared to commonly used transposed convolutions, the authors’ ESRR module has fewer computational cost. Considering that the haze distribution is always uneven and the information from each channel is different, the authors introduce the Dynamic Multi‐Attention (DMA) module to provide pixel‐wise weights and channel‐wise weights for input features. The authors place the DMA module between the encoder and decoder parts. As the network depth increases, the spatial structural information from the high‐resolution layer tends to degrade. To deal with the problem, the authors propose the Multi‐Scale Feature Fusion (MSFF) module to recover missing spatial structural information. The authors place the MSFF module in both the encoder and decoder parts. Extensive experimental results show that the authors’ proposed dehazing network achieves state‐of‐the‐art dehazing performance with relatively low computational cost.
Sonographisch gestützte Identifikation des Ligamentum conicum in der Kopf-Hals-Ultraschalllehre
Authors: Weimer Andreas Michael , Weimer Johannes Matthias , Jonck Christopher , Müller Lukas , Stäuber Marie , Chrissostomou Christopher David , Buggenhagen Holger , Klöckner Roman , Pirlich Nina , Künzel Julian , Rink Maximilian 
Published: June 2024

Zusammenfassung
Hintergrund Verlegungen der oberen Atemwege stellen akute Notfälle dar. Ultima Ratio zur Sicherung der Atemwege ist die Durchführung einer Koniotomie nach Identifizierung des Lig. conicum. Hier kann die Sonografie unterstützen. Ziel dieser Studie war die Etablierung eines Trainings zur Vermittlung dieser Kompetenzen.
Material Methoden Das Training bestand aus einer theoretischen Schulung mit anschließender Videopräsentation (je 10min) sowie einem praktischen Training (45min). Zur Messung der Vorerfahrungen, der Zufriedenheit mit dem Training sowie des subjektiven und objektiven Kompetenzlevels wurden vor (T1) und nach (T2) dem Training Evaluationen bearbeitet. Zu T2 wurde zudem eine praktische Prüfung von n=113 Teilnehmenden (TN) absolviert. Die Ergebnisse der praktischen Prüfung wurden durch einen standardisierten Bogen dokumentiert.
Ergebnisse Der größte Teil der TN hatte weder eine Koniotomie gesehen (64,6%) noch eigenständig durchgeführt (79,6%). In der subjektiven Kompetenzeinschätzung konnte eine signifikante Verbesserung (T1 zu T2) gemessen werden (p<0,001). Das Trainingsprogramm wurde in allen abgefragten Items positiv bewertet. In den praktischen Prüfungen erreichten die TN durchschnittlich 89,2% der möglichen Punkte und benötigten für die Identifizierung des Lig. conicum im Mittelwert 101±23 Sekunden.
Schlussfolgerung Strukturiertes Training zur sonografischen Identifizierung des Lig. conicum führt bereits in kurzer Zeit zu einer deutlichen Verbesserung der subjektiven Kompetenzen sowie zu einem hohen objektiven Kompetenzlevel. Zukünftig sollten solche Trainingsprogramme standardisiert in der Kopf-Hals-Ultraschallausbildung etabliert werden.
Lower Uterine Segment Corrugated Sutures in Hemorrhage during
Cesarean Section because Previal and/or Placenta Accreta Spectrum: Case Reports
Series and Literature Review
Authors: Habek Dubravko , Mikuš Mislav , Cerovac Anis 
Published: June 2024

Abstract
Objectives We present the original technique of compression hemostatic
sutures on the lower uterine segment due to early postpartum hemorrhage during
cesarean section, with a literature review.
Methods A retrospective clinical case study was conducted at the tertiary
perinatal center. Twelve patients had nine planned and three urgent cesarean
sections due to antenatally verified placenta previa and/or placenta accreta
spectrum and defined early postpartum hemorrhage > 1000 mL during cesarean
section. As the use of uterotonics failed to produce any effect and hemorrhage
persisted, compression sutures of the lower uterine segment were made by our own
technique, as follows: below the hysterotomy, a horizontal corrugated suture is
placed from the right to the left corner and after 2–3 cm vertically and
backwards at several sites from the left to the right corner, where it is
tightened.
Results Seven patients had one cesarean section, three patients had two
cesarean sections, and seven patients had pregnancy from the in vitro
fertilization procedure in their history. There were six patients with placenta
previa and six patients with anterior invasive placenta accreta or increta.
Original hemostatic procedure was applied successfully in ten cases, and after
placement of O'Leary suture and persistent bleeding in two cases. In this
group, no hysterectomy was performed, and patients received blood transfusion of
440–880 mL. Three patients later had spontaneous pregnancies.
Conclusion Our own hemostatic method with a simple technique, fast
learning, and minimal logistics contributes to successful management of this
currently global problem of morbidly adherent placenta previa.
Minimal Learning Curve for Minimally Invasive Aortic Valve Replacement
Authors: Leviner Dror B. , Ronai Tom , Abraham Dana , Eliad Hadar , Schwartz Naama , Sharoni Erez 
Published: June 2024

Abstract
Background Minimally invasive aortic valve replacement (MiAVR) is an established technique for surgical aortic valve replacement (AVR). Although MiAVR was first described in 1993 and has shown good results compared with full sternotomy AVR (FSAVR) only a minority of patients undergo MiAVR. We recently started using MiAVR via an upper hemisternotomy. We aimed to examine the early results of our initial experience with this technique.
Methods We compared 55 MiAVR patients with a historical cohort of 142 isolated FSAVR patients (December 2016–December 2022). The primary outcome was in-hospital mortality. Secondary outcomes included cardiopulmonary bypass (CPB) and cross-clamp times, blood product intake, in-hospital morbidity, and length of intensive care unit and hospital stay.
Results There was no significant difference in preoperative characteristics, including age, laboratory values, and comorbidities. There was no significant difference between the groups regarding in-hospital mortality (FSAVR 3.52 vs. MiAVR 1.82%). There was no significant difference in CPB time (FSAVR 103.5 [interquartile range: 82–119.5] vs. MiAVR 107 min [92.5–120]), aortic cross-clamp time (FSAVR 81 [66–92] vs. MiAVR 90 min [73–99]), and valve size (FSAVR 23 [21–25] vs. MiAVR 23 [21–25]). The incidence of intraoperative blood products transfusion was significantly lower in the MiAVR group (10.91%) compared with the FSAVR group (25.35%, p = 0.03).
Conclusion Our findings further establish the possibility of reducing invasiveness of AVR without compromising patient safety and clinical outcomes. This is true even in the learning curve period and without requiring any significant change in the operative technique and dedicated equipment.
Recyclable Palladium-Catalyzed Carbonylative Coupling of Aryl Halides and Organoaluminum Compounds with tert-Butyl Iso­cyanide as CO Equivalent Leading to 1,2-Diketones
Authors: You Shengyong , Cai Mingzhong , Tu Zhiyuan , Zhan Jianan 
Published: June 2024

AbstractAn efficient heterogeneous palladium-catalyzed carbonylative coupling of aryl halides and organoaluminum compounds has been developed using tert-butyl isocyanide as CO equivalent. The carbonylation reaction proceeds smoothly in toluene with KOtBu as a base at 100 °C by using 10 mol% of an SBA-15-anchored bidentate phosphine palladium(0) complex [2P-SBA-15-Pd(0)] as the catalyst and provides a general and practical approach for the assembly of 1,2-diketones in good to excellent yields. This heterogenized palladium catalyst can be readily separated and recovered via a simple centrifugation process and reused for more than seven cycles with almost consistent catalytic efficiency.
Subluxação intrabainha dos tendões fibulares: Relato de três casos com nota técnica
Authors: Lima Cunha Raquel , Castro Alexandre , Atilano Carvalho Pedro , Gomes Marta , Miranda António , Teixeira João 
Published: June 2024

ResumoA instabilidade intrabainha fibular provoca dor com estalo e clique audível na lateral do tornozelo. Esta doença é pouco relatada e sua incidência exata é desconhecida. Consiste em uma subluxação retromaleolar transitória dos tendões fibulares com movimento anormal dos tendões fibulares entre si e integridade do retináculo fibular superior. O diagnóstico requer alta suspeita clínica e a ultrassonografia dinâmica é o melhor estudo de imagem para avaliação da instabilidade fibular quando o retináculo fibular superior está intacto para detecção de instabilidade intrabainha fibular. O objetivo do presente estudo é descrever como chegar ao diagnóstico e relatar e avaliar a técnica cirúrgica para o tratamento desta doença. Neste relato, descrevemos três casos da doença que foram submetidos ao tratamento cirúrgico com sucesso com procedimento de aprofundamento do sulco fibular e retinuloplastia do retináculo superior. Esta técnica cirúrgica proporciona bons resultados em caso de falha do tratamento conservador.
Europeanisation in the aftermath of COVID-19: the organisational adaptation of the central governance of the National Recovery and Resilience Plan in Italy
Authors: Bressanelli Edoardo , Natali David 
Published: June 2024

AbstractWhile much of the recent literature on the impact of COVID-19 has focussed on governance at the EU level and specific policy areas, the changing political institutional arrangements within the EU Member States themselves have received significantly less attention. This article aims to contribute filling this gap by asking: how, and to what extent, has the core executive in Italy changed to manage and implement the National Recovery and Resilience Plan (NRRP)? Italy has been heavily hit by the COVID-19 pandemic and has subsequently been allocated the largest proportion of the Next Generation EU (NGEU) funds: it is therefore a ‘most likely’ case of organisational adaptation. We argue that the implementation of the NRRP triggers centralisation of power in the core executive. Such concentration of power, however, takes different forms depending on the composition of the executive. We also find that ‘coordinative’ Europeanisation occurs through the continuous interaction and exchange between the executive actors (political and administrative) based in Rome and the European Commission in Brussels. Such interaction showcases the attempt to manage both further integration and politicisation of the EU. The collaboration between the European Commission and the national executive is based both on the recognition of the value of the political ownership of the NRRP and the importance of the EU support for post-pandemic recovery.
Observation of the early stages of environmental contamination in graphene by friction force
Authors: Almeida Clara M. , Ptak Felipe , Prioli Rodrigo 
Published: June 2024

Exposure to ambient air contaminates the surface of graphene sheets. Contamination may arise from different sources, and its nature alters the frictional behavior of the material. These changes in friction enable the observation of the early stages of contaminants’ adsorption in graphene. Using a friction force microscope, we show that molecular adsorption initiates at the edges and mechanical defects in the monolayer. Once the monolayer is covered, the contaminants spread over the additional graphene layers. With this method, we estimate the contamination kinetics. In monolayer graphene, the surface area covered with adsorbed molecules increases with time of air exposure at a rate of 10−14 m2/s, while in bilayer graphene, it is one order of magnitude smaller. Finally, as the contaminants cover the additional graphene layers, friction no longer has a difference concerning the number of graphene layers.
Role of Griffiths phase on magnetocaloric properties and critical behavior of half-doped manganites [La0.5Sr0.5−xCaxMnO3(x = 0, 0.25, 0.5)]
Authors: Mandal Sibasish , Mohanty Sipun , Chakravarty Sujay , Mukherjee Samrat 
Published: June 2024

In this article, a comprehensive study of the effect of calcium substitution on structural magnetic, magnetocaloric properties, and role of Griffiths phase on magnetocaloric properties of half-doped manganites La0.5Sr0.5−xCaxMnO3(x=0,0.25,0.5)] have been presented. A structural phase transition I4/mcm − Pbnm is observed in the whole series. The system exhibits two magnetic transitions for Ca-00 and Ca-25, whereas only one phase transition is observed for Ca-50. Paramagnetic (PM)–ferromagnetic (FM) transition is observed in the whole series and ferromagnetic (FM) - antiferromagnetic (AFM) phase transition is only observed in Ca-25. Interestingly, short range FM clusters exist in the PM matrix of Ca-50, which is a signature of Griffiths phase (GP). The confirmation of GP has been carried out by performing iso-field magnetization measurements at 200 Oe, 500 Oe, and 1 kOe, respectively. Further magnetocaloric properties have been discussed on the basis of isothermal magnetization curves recorded at certain temperature intervals. Calcium substitution favors the enhancement of magnetic entropy change in the series, especially for Ca-50, a magnetic entropy change of 4.5 J/(kg K) with relative cooling power of 180 J/kg under 5 T magnetic field was observed. Iso-field magnetization and magnetocaloric effect along with critical behavior analysis have been carried out to probe the GP and other inhomogeneities present in the respective series.
Variant patterns of sibilant debuccalization in Camuno
Authors: Blevins Juliette , Cresci Michela 
Published: June 2024

Abstract
Some varieties of Camuno, an Eastern Lombard variety spoken in Valcamonica, Italy, show clear evidence of what
appears to be an unconditioned sound change of S > h, where S had [s] and [θ] variants (Bonfadini 1995a; Cresci 2014). However,
neighboring varieties in the upper parts of the valley retain inherited S and, in at least one village, Cerveno,
debuccalization is limited to intervocalic position. In this study, we attempt to explain dialect variation in Camuno in terms of
s-debuccalization as a lenition process within the general framework of Evolutionary Phonology (Blevins 2004a, 2006, 2015) building on the typology established by Ferguson (1990).
The probability of articulatory undershoot is greatest in the V_V environment, and all dialects with S > h
show the sound change in this context. In medial clusters like rS, lS, nS, where there is articulatory overlap
and longer sustained constriction, articulatory undershoot is less likely, and S is most likely to be maintained, as it is in
Cerveno. A treatment of S > h as lenition implies that [s] and [θ] were produced with spread vocal folds in languages where
this sound change has been observed. Here we offer additional evidence for aspiration as an active feature in Camuno phonology and
suggest possible origins of this feature during the long period of contact with Longobardic. Another central issue explored in
this study are phonetic factors that might differentiate intervocalic s > h from s > h that originates in the syllable coda,
as in many varieties of Spanish.
Sustainable Tourism in Galapagos: The Perception of the Stakeholders
Authors: Soto-Navarrete Lady Maria , Saladié Òscar 
Published: June 2024

Summary
The Galapagos Islands (Ecuador) are a living laboratory and a sensitive area where, among other activities, tourism is performed. The unique flora, fauna, and landscapes motivate thousands of people to visit the islands every year, generating economic benefits and various considerations regarding environmental issues.

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