bluuebunny/crossref_metadata_2025_split huggingface dataset:
NeuroPedia: neuropeptide database and spectral library
Authors: Kim Yoona , Bark Steven , Hook Vivian , Bandeira Nuno 
Published: August 2011

Abstract
Summary: Neuropeptides are essential for cell–cell communication in neurological and endocrine physiological processes in health and disease. While many neuropeptides have been identified in previous studies, the resulting data has not been structured to facilitate further analysis by tandem mass spectrometry (MS/MS), the main technology for high-throughput neuropeptide identification. Many neuropeptides are difficult to identify when searching MS/MS spectra against large protein databases because of their atypical lengths (e.g. shorter/longer than common tryptic peptides) and lack of tryptic residues to facilitate peptide ionization/fragmentation. NeuroPedia is a neuropeptide encyclopedia of peptide sequences (including genomic and taxonomic information) and spectral libraries of identified MS/MS spectra of homolog neuropeptides from multiple species. Searching neuropeptide MS/MS data against known NeuroPedia sequences will improve the sensitivity of database search tools. Moreover, the availability of neuropeptide spectral libraries will also enable the utilization of spectral library search tools, which are known to further improve the sensitivity of peptide identification. These will also reinforce the confidence in peptide identifications by enabling visual comparisons between new and previously identified neuropeptide MS/MS spectra.
Availability: http://proteomics.ucsd.edu/Software/NeuroPedia.html
Contact: bandeira@ucsd.edu
Supplementary information: Supplementary materials are available at Bioinformatics online.
Medicago truncatula CYP716A12 Is a Multifunctional Oxidase Involved in the Biosynthesis of Hemolytic Saponins
Authors: Carelli Maria , Biazzi Elisa , Panara Francesco , Tava Aldo , Scaramelli Laura , Porceddu Andrea , Graham Neil , Odoardi Miriam , Piano Efisio , Arcioni Sergio , May Sean , Scotti Carla , Calderini Ornella 
Published: August 2011

Abstract
Saponins, a group of glycosidic compounds present in several plant species, have aglycone moieties that are formed using triterpenoid or steroidal skeletons. In spite of their importance as antimicrobial compounds and their possible benefits for human health, knowledge of the genetic control of saponin biosynthesis is still poorly understood. In the Medicago genus, the hemolytic activity of saponins is related to the nature of their aglycone moieties. We have identified a cytochrome P450 gene (CYP716A12) involved in saponin synthesis in Medicago truncatula using a combined genetic and biochemical approach. Genetic loss-of-function analysis and complementation studies showed that CYP716A12 is responsible for an early step in the saponin biosynthetic pathway. Mutants in CYP716A12 were unable to produce hemolytic saponins and only synthetized soyasaponins, and were thus named lacking hemolytic activity (lha). In vitro enzymatic activity assays indicate that CYP716A12 catalyzes the oxidation of β-amyrin and erythrodiol at the C-28 position, yielding oleanolic acid. Transcriptome changes in the lha mutant showed a modulation in the main steps of triterpenic saponin biosynthetic pathway: squalene cyclization, β-amyrin oxidation, and glycosylation. The analysis of CYP716A12 expression in planta is reported together with the sapogenin content in different tissues and stages. This article provides evidence for CYP716A12 being a key gene in hemolytic saponin biosynthesis.
Efficiency in agricultural commodity futures markets in India
Authors: Ali Jabir , Bardhan Gupta Kriti 
Published: August 2011

PurposeIn line with the ongoing global and domestic reforms in agriculture and allied sectors, the Indian Government is reducing its direct market intervention and encouraging private participation based on market forces. This has led to increased exposure of agricultural produce to price and other market risks, which consequently emphasize the importance of futures markets for price discovery and price risk management. The purpose of this paper is to analyze the efficiency of agricultural commodity markets by assessing the relationships between futures prices and spot market prices of major agricultural commodities in India.Design/methodology/approachThe efficiency of the futures market for 12 agricultural commodities, traded at one of the largest commodity exchanges of India, i.e. National Commodity & Derivatives Exchange Ltd, has been explored by using Johansen's cointegration analysis and Granger causality tests. Unit root test procedures such as Augmented Dickey‐Fuller and non‐parametric Phillips‐Perron were initially applied to examine whether futures and spot prices are stationary or not. The hypothesis, that futures prices are unbiased predictors of spot prices has been tested using econometric software package.FindingsResults show that cointegration exists significantly in futures and spot prices for all the selected agricultural commodities except for wheat and rice. This suggest that there is a long‐term relationship between futures and spot prices for most of the agricultural commodities like maize, chickpea, black lentil, pepper, castor seed, soybean and sugar. The causality test further distinguishes and categorizes the commodities based on direction of relationship between futures and spot prices. The analysis of short‐term relationship by causality test indicates that futures markets have stronger ability to predict subsequent spot prices for chickpea, castor seed, soybean and sugar as compared to maize, black lentil and pepper, where bi‐directional relationships exist in the short run.Practical implicationsThe results of this study are useful for various stakeholders active in agricultural commodities markets such as producers, traders, commission agents, commodity exchange participants, regulators and policy makers.Originality/valueThere are very few studies that have explored the efficiency of the commodity futures market in India in a detailed manner, especially at individual commodity level.
Regulation and the financial performance of Canadian agribusinesses
Authors: Schaufele Brandon , Sparling David 
Published: August 2011

PurposeThe purpose of this paper is to investigate the relationships between regulatory changes, returns on equity and stock market valuations for Canadian food and non‐food agribusinesses.Design/methodology/approachTwo empirical approaches are employed. First, an event study is used to evaluate the impact of official regulatory announcements on the stock market valuations of selected Canadian agribusinesses. Next, an approach introduced by Mishra et al. using the Du Pont expansion is applied to investigate the effect of regulations on firms' accounting profits. Data on Canadian food and non‐food agribusinesses are collected from Bloomberg, Thompson One Banker and SEDAR.FindingsThe event study demonstrates that official regulatory announcement dates do not correspond with abnormal stock market returns for Canadian firms, while the Du Pont model yields mixed evidence with respect to their accounting profits.Research limitations/implicationsThis paper only considers publicly traded companies. As a result, survivorship bias may exist. Future research should include privately held and cooperative firms.Social implicationsFood regulations can influence firm profits and shareholder wealth, so understanding how government actions influence agribusiness is important when considering the total costs of current and future food policy.Originality/valueThe interaction between policy and the financial performance of Canada's publicly traded agribusinesses is an under‐researched area and no studies have examined Canadian data. The results of this study are valuable to both policy makers and researchers.
Farmer demand for financial record‐keeping system attributes
Authors: Wolf Christopher A. , Lupi Frank , Harsh Stephen 
Published: August 2011

PurposeThe purpose of this paper is to determine which financial record‐keeping system farmers use, as well as what system attributes farmers value and to what degree.Design/methodology/approachThis research uses a choice experiment to examine farmer's demand for attributes of financial record‐keeping systems. A sample from the general Michigan farm population is compared to samples from university and agribusiness record system clients.FindingsResults reveal that university and agribusiness clients are willing to pay considerably more for a farm‐specific record system to backstop their farm management decisions.Practical implicationsThe results provide an understanding of farmer demands for farm financial record systems and can be used to position record‐keeping systems to meet those demands.Originality/valueThis paper describes and analyzes farm financial accounting system use and preferences by type.
Which mode is better for knowledge creation?
Authors: Kao Shu‐Chen , Wu ChienHsing , Su Ping‐Chieh 
Published: August 2011

PurposeThe purpose of this paper is to examine the impact of knowledge creation mode (e.g. goal‐driven and goal‐free) and organizational culture on knowledge creation performance in the context of high‐tech manufacturing companies having received at least 20 patents.Design/methodology/approachThis paper uses an empirical study to examine the research model.FindingsBoth goal‐free and goal‐framed creation modes are more likely to support knowledge creation, while the goal‐driven mode is not likely to be favorable for knowledge creation. Manufacturing companies who are frequently looking for new ideas for product design and manufacturing technologies are more likely to adopt the goal‐free creation mode. Adhocracy culture is more likely to be a predicator of product and manufacturing creation.Practical implicationsThis work provides policy implications for government and high‐tech industry associations. A company whose cohesion comes mainly from the task achievements is likely to emphasize manufacturing creation. Companies who would like to emphasize goal achievement with respect to creation in manufacturing should form an organizational culture with a characteristic of market competition. Also, a company with both goal‐free and/or goal‐framed creation modes is more likely to be willing to frame its strategic decisions (or goals) and then freely look for creative ways to reach the goals.Originality/valueManufacturing creation‐based companies are becoming increasingly knowledge‐sensitive as the competition becomes more intense, and thus may try multiple modes of knowledge creation to strengthen their creation capability in some areas. The research findings are quite remarkable because the impacts of culture and creation mode on creation performance are statistically examined.
Intellectual capital disclosure payback
Authors: Curado Carla , Henriques Lopes , Bontis Nick 
Published: August 2011

PurposeThe purpose of this paper is to propose an integrated framework for intellectual capital disclosure.Design/methodology/approachThe measure, manage and report intellectual capital (MMRIC) methodology is a six‐step process that will enable firms to more accurately describe their intangible assets.FindingsThe proposed step‐by‐step process also complements the exploration‐exploitation tension that is highlighted in the knowledge management literature.Research limitations/implicationsThis paper provides academic researchers with a comprehensive framework that can be utilized for future empirical studies related to intellectual capital disclosure.Practical implicationsThe MMRIC process is a very useful tool for practitioners in that it provides a sequential system that can be followed for intellectual capital disclosure.Social implicationsSociety at large benefits when corporate entities help to reduce risk and volatile market fluctuations by reducing information asymmetry with more comprehensive reporting.Originality/valueThis paper provides an initial theoretical framework that has been developed by integrating the extant literature on intellectual capital disclosure.
Variations in evaluative repertoires
Authors: Pernkopf‐Konhäusner Katharina , Brandl Julia 
Published: August 2011

PurposeWhile it is acknowledged that societal context matters for employee expectations on training and development, the complexity of this relationship is still little explored. This paper aims to study which higher‐order principles employees of a German and Russian company use to justify their views on beneficial training and development in order to identify how evaluative repertoires differ between the two settings.Design/methodology/approachBuilding on interviews conducted in two professional services firms in Germany and Russia, the paper identifies patterns in the repertoire that employees use for evaluating training and development activities at each research site.FindingsThe findings reveal that employees working for the German company predominantly use the industrial principle for justifying their views on training and development. In contrast, employees in the Russian company apply market, industrial and domestic principles with a tendency for long‐term employees more often to justify their views using the market principle.Research limitations/implicationsThe case comparison points to variations in the evaluative repertoire that the paper explains with the societal context of Germany and Russia. By examining evaluative repertoires, companies learn what employees expect from training and development.Originality/valueApplying convention theory, the paper introduces a promising, but so far neglected approach for linking employee expectations with societal context and for comparing boundaries between people across different settings.
Employment relationships as drivers of firm flexibility and learning
Authors: López‐Cabrales Alvaro , Valle Ramon , Galan Jose L. 
Published: August 2011

PurposeThis paper seeks to analyse whether the firm model of employment relationships is associated with functional flexibility and organisational learning (exploratory versus exploitative). It also aims to assess the mediating effect of functional flexibility in the relationship between a specific employment mode (mutual investment) and organisational learning.Design/methodology/approachThis research was conducted using a sample of Spanish companies in the food industry, from which data from HR managers and production managers in each firm were collected. Cluster analyses, MANOVA and regression analyses were applied to test the hypotheses.FindingsThe results suggest that those firms developing a mutual investment employment relationship outperform other firms in terms of functional flexibility and organisational learning (both exploitative and exploratory learning). The paper also finds a mediating effect of one dimension of functional flexibility (range‐number of activities) between mutual investment and exploitative learning.Research limitations/implicationsThe principal limitation of this paper is the cross‐sectional study design, because the dynamic character of learning would require a longitudinal study design. The main research implications are derived from the combination of employment relationships, variety of dimensions of flexibility and learning, and identification of a model of direct and mediating effects among variables.Practical implicationsThe results of this paper suggest that a model of employment relationships (mutual investment) favours not only functional flexibility but also ambidextrous learning. Thus, the findings not only provide a broader understanding of the variables associated with HRM, employment relationships and/or flexibility, but also reinforce the strategic role of HRM through its contribution to the development of such a relevant organisational capability that learning represents.Originality/valueThe paper combined a series of variables that previous studies have rarely treated in combination: employment relationships, functional flexibility and exploitative versus exploratory learning. This paper also discusses different dimensions of functional flexibility (range‐number of activities, heterogeneity, mobility, and uniformity), demonstrating the association of some of these dimensions with exploratory or exploitative learning.
Under‐employment among recent graduates: a review of the literature
Authors: Scurry Tracy , Blenkinsopp John 
Published: August 2011

PurposeThe purpose of this paper is to offer a systematic review of the literature that explores under‐employment among recent graduates. Literature from a range of disciplines is reviewed in an attempt to further a theoretical understanding. In doing this, the secondary aim is to identify avenues for future research.Design/methodology/approachThe paper adopts a systematic literature review methodology to answer the question “What is graduate underemployment?”FindingsThe review highlights significant issues around the conceptualisation and measurement of graduate under‐employment. It argues that individual volition and meaning making are important issues that to date remain under‐researched in relation to graduate under‐employment. The paper argues that the most appropriate basis for developing a theoretical understanding of graduate under‐employment is to draw upon relevant theoretical frameworks from career studies – specifically those on the objective‐subjective duality of career, career indecision, and career success. This approach provides a greater focus on the dynamics of the individual's experiences.Practical implicationsThis review has implications for a range of stakeholders including students, graduates, teachers and careers advisers, parents, universities, employers, HR professionals and policy makers.Originality/valueIn the context of policy debates surrounding the purpose and value of higher education, this review brings together the highly fragmented perspectives on a phenomenon that encapsulates many of the issues being debated.
Recent developments in adhesive technology: a review
Authors: Bogue Robert 
Published: August 2011

PurposeThis paper aims to provide an insight into recent developments in adhesive technology.Design/methodology/approachFollowing a brief introduction, this paper discusses recent developments in biomimetic adhesives, the use of nanomaterials and “smart” adhesive technology.FindingsBiomimetic dry adhesive technology has advanced very rapidly in recent years and techniques to mass‐produce these materials are now under development. The use of nanomaterials is being investigated widely and recent research suggests that adhesives with enhanced mechanical, thermal and electrical properties will emerge. Smart adhesives, such as switchable types which can be triggered to bond and de‐bond in response to physical or chemical stimuli are under development and some are already available commercially. These will contribute to product disassembly and recycling.Originality/valueThis paper provides a review of recent R&D into three fields of adhesive technology that are presently attracting strong interest.
Using selective laser sintering for manufacturing
Authors: Butler James 
Published: August 2011

PurposeThe purpose of this paper is to describe the basics of selective laser sintering (SLS) and also the benefits of designing parts to be built using this technology. Some design requirements are also included.Design/methodology/approachThis paper was written to assist design engineers in using the SLS technology as opposed to traditional manufacturing technologies.FindingsThe findings of the paper are primarily limited to the differences of the functionality of products designed for manufacture using traditional technologies as compared to the ability to design for perfect functionality and the parts are able to be manufactured using SLS.Originality/valueThe paper shows that any application where light weight, maximum performance or the ability to customize is the prime consideration is a candidate for the many benefits afforded by SLS and the related technologies.
Integration of PCB assembly process planning and scheduling
Authors: Du Xuan , Li Zongbin , Wang Song 
Published: August 2011

PurposeThe purpose of this paper is to realize the integrated optimization of process planning and scheduling in printed circuit board assembly (PCBA).Design/methodology/approachLogical and numerical contour matrix is used to describe the constituent of component and machine for different PCBA processes on the basis of polychromatic sets (PS) theory, and a PS model of PCBA is built. A hybrid genetic algorithm (GA) is developed to optimize the component allocation, PCB assignment and assembly sequence simultaneously.FindingsIntegration of PCBA process planning and scheduling (PCBAPPS) can bridge the gap between design and manufacturing to guarantee the assembly quality and improve the production efficiency. However, PCBAPPS have to search for the optimal result in their own vast solution space. They are complex combinatorial optimization problems. The optimization of PCBAPPS constructs a unified solution space which includes two sub‐solution space stated above. In this paper, dynamic optimization of PCBAPPS is implemented and the solution efficiency is improved.Originality/valuePS model holds unified standard form on the basis of logical contour and numerical matrix. It is adopted to describe the static structure and dynamic characteristic of PCBA system and combine with GA to solve the integrated optimization problem of PCBAPPS effectively and dynamically.
Automatic inspection and strategy for surface defects in the PI coating process of TFT‐LCD panels
Authors: Lin Chern‐Sheng , Kuo Jung , Lin Chi‐Chin , Lay Yun‐Long , Shei Hung‐Jung 
Published: August 2011

PurposeThe purpose of this paper is to apply an on‐line automatic inspection and measurement of surface defect of thin‐film transistor liquid‐crystal display (TFT‐LCD) panels in the polyimide coating process with a modified template matching method and back propagation neural network classification method.Design/methodology/approachBy using the technique of searching, analyzing, and recognizing image processing methods, the target pattern image of TFT‐LCD cell defects can be obtained.FindingsWith template match and neural network classification in the database of the system, the program judges the kinds of the target defects characteristics, finds out the central position of cell defect, and analyzes cell defects.Research limitations/implicationsThe recognition speed becomes faster and the system becomes more flexible in comparison to the previous system. The proposed method and strategy, using unsophisticated and economical equipment, is also verified. The proposed method provides highly accurate results with a low‐error rate.Practical implicationsIn terms of sample training, the principles of artificial neural network were used to train the sample detection rate. In sample analysis, character weight was implemented to filter the noise so as to enhance discrimination and reduce detection.Originality/valueThe paper describes how pre‐inspection image processing was utilized in collaboration with the system to excel the inspection efficiency of present machines as well as for reducing system misjudgment. In addition, the measure for improving cell defect inspection can be applied to production line with multi‐defects to inspect and improve six defects simultaneously, which improves the system stability greatly.