bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epitope Mapping Using Gram‐Positive Surface Display
Authors: Rockberg Johan , Löfblom John , Hjelm Barbara , Ståhl Stefan , Uhlén Mathias 
Published: September 2010

AbstractAntibodies have proven to be invaluable tools for a vast number of applications during the last decades, including protein purification and characterization, medical diagnosis and imaging, and treatment using therapeutic antibodies. No matter what the aims of the application are, the antibody's binding characteristics will still be the main features determining the assay's reliability. Here, we describe a protocol for determination of antibody‐binding epitopes using an antigen‐focused, library‐based approach where library members are generated by fragmentation of antigen DNA and presented as cloned peptides on the cell surface of the Gram‐positive bacterium Staphylococcus carnosus. The rigid cell structure of this organism allows for multivalent expression and permits rapid library analysis and sorting of antibody‐binding cells using flow‐sorting devices. Epitopes are determined by DNA sequencing of the sorted cells and alignment back to the antigen sequence. The protocol described here has been shown useful for mapping of both monoclonal and polyclonal binders with varying epitope lengths. Curr. Protoc. Immunol. 90:9.9.1‐9.9.17. © 2010 by John Wiley & Sons, Inc.
Preparation, Characterization, and Application of Optical Switch Probes
Authors: Petchprayoon Chutima , Marriott Gerard 
Published: September 2010

AbstractOptical switches represent a new class of molecular probe with applications in high‐contrast imaging and optical manipulation of protein interactions. Small molecule, organic optical switches based on nitrospirobenzopyran (NitroBIPS) and their reactive derivatives and conjugates undergo efficient, rapid and reversible, orthogonal optically‐driven transitions between a colorless spiro (SP)‐state and a colored merocyanine (MC)‐state. The excited MC‐state also emits fluorescence, which serves as the readout of the state of the switch. Defined optical perturbations of SP and MC generate a defined waveform of MC‐fluorescence that can be isolated against unmodulated background signals by using a digital optical lock‐in detection approach or to control specific dipolar interactions on proteins. The protocols describe general procedures for the synthesis and spectroscopic characterization of NitroBIPS and specifically labeled conjugates along with methods for the manipulation of dipolar interactions on proteins and imaging of the MC‐state of NitroBIPS within living cells. Curr. Protoc. Chem. Biol. 2:153‐169 © 2010 by John Wiley & Sons, Inc.
Experimental Design Considerations for In Vitro Non‐Natural Glycan Display via Metabolic Oligosaccharide Engineering
Authors: Tan Elaine , Almaraz Ruben T. , Khanna Hargun S. , Du Jian , Yarema Kevin J. 
Published: September 2010

AbstractMetabolic oligosaccharide engineering (MOE) refers to a technique where non‐natural monosaccharide analogs are introduced into living biological systems. Once inside a cell, these compounds intercept a targeted biosynthetic glycosylation pathway and in turn are metabolically incorporated into cell‐surface‐displayed oligosaccharides where they can modulate a host of biological activities or be exploited as “tags” for bio‐orthogonal and chemoselective ligation reactions. Undertaking a MOE experiment can be a daunting task based on the growing repertoire of analogs now available and the ever increasing number of metabolic pathways that can be targeted; therefore, a major emphasis of this article is to describe a general approach for analog design and selection and then provide protocols to ensure safe and efficacious analog usage by cells. Once cell‐surface glycans have been successfully remodeled by MOE methodology, the stage is set for probing changes to the myriad cellular responses modulated by these versatile molecules. Curr. Protoc. Chem. Biol. 2:171‐194 © 2010 by John Wiley & Sons, Inc.
Insulin‐like growth factor 1 synergizes with bone morphogenetic protein 7–mediated anabolism in bovine intervertebral disc cells
Authors: Kim Jae‐Sung , Ellman Michael B. , An Howard S. , van Wijnen Andre J. , Borgia Jeffrey A. , Im Hee‐Jeong 
Published: September 2010

AbstractObjectiveWe undertook this study to assess the therapeutic benefits of intervertebral disc matrix repair and regeneration by evaluating the potential synergistic effect of insulin‐like growth factor 1 (IGF‐1) and bone morphogenetic protein 7 (BMP‐7) on bovine spine discs and by elucidating the relevant molecular/cellular mechanisms.MethodsBovine nucleus pulposus (NP) cells were treated with BMP‐7 and IGF‐1. The subsequent anabolic effects driven by NP cells were assessed for proteoglycan (PG) synthesis by 35S‐sulfate incorporation and for PG accumulation by dimethylmethylene blue assays. Matrix formation was visualized by particle exclusion assay. Key matrix components and transcription factors were analyzed by real‐time reverse transcription–polymerase chain reaction to determine the signaling pathways by which IGF‐1 suppresses noggin, a potent inhibitor of BMP‐7. Western blotting and nuclear translocation experiments were performed to assess the activation of Smad proteins.ResultsStimulation of bovine NP cells by both IGF‐1 and BMP‐7 greatly potentiated anabolism through complementary and synergistic mechanisms on matrix formation compared with treatment with either growth factor alone. The exogenously added decoy ligand, noggin, attenuated the anabolic effects of BMP‐7, and noggin was substantially increased by BMP‐7, suggesting a negative feedback regulatory mechanism. In contrast, IGF‐1 significantly suppressed noggin expression via the phosphatidylinositol 3‐kinase/Akt pathway and thus potentiated BMP‐7 signaling in bovine NP cells. Upon combination treatment, IGF‐1 activated Smad2, while BMP‐7 activated Smad1/5/8 and Smad3, thus inducing all Smad signaling pathways and mimicking the effects of the combination of transforming growth factor β and BMP‐7ConclusionCombination growth factor therapy using BMP‐7 and IGF‐1 may have considerable promise in the treatment of spine disc degeneration.
ChemInform Abstract: Sodium and Silver Environments and Ion‐Exchange Processes in Silicate and Aluminosilicate Glasses.
Authors: HOUDE‐WALTER S. N. , INMAN J. M. , DENT A. J. , GREAVES G. N. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Influence of the Stereochemistry of Water Coordination to Metal(III) Cations on the M‐O Bond Length and Electronic Structure of the Cation.
Authors: BEST S. P. , FORSYTH J. B. , TREGENNA‐PIGGOTT P. L. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction Kinetics and Mechanism of Formation of (MnMo9O32)6‐ by Hypochlorous Acid Oxidation of Mn2+(aq) in the Presence of Molybdate.
Authors: ANGUS‐DUNNE S. J. , IRWIN J. A. , BURNS R. C. , LAWRANCE G. A. , CRAIG D. C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure of K3Na4H2(GdW10O36)×21 H2O.
Authors: YAMASE T. , OZEKI T. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure of UOSe.
Authors: MANSUETTO M. F. , JOBIC S. , NG H. P. , IBERS J. A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses and Structures of Two Large Iodoantimonate Anions.
Authors: CARMALT C. J. , NORMAN N. C. , FARRUGIA L. J. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Compounds with KTiOPO4‐Structure: NaSbOGeO4, AgSbOGeO4 and AgSbOSiO4.
Authors: MILL' B. V. , BUTASHIN A. V. , STEFANOVICH S. YU. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Orthorhombic Mg4IrD5 with Disordered Deuterium Distribution.
Authors: BONHOMME F. , STETSON N. T. , YVON K. , FISCHER P. , HEWAT A. W. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Structure and Bonding of nido‐7,9‐X2B9H9 (X: S or Se).
Authors: DHUBHGHAILL O. N. , REED D. , SPALDING T. R. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure of a 2‐Arylquinoline Dimer, a Compound with a New Ring System.
Authors: AMMON H. L. , REID T. L. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure of 2‐Methoxycarbonyl‐1,4‐dinitrocubane.
Authors: AMMON H. L. , BASHIR‐HASHEMI A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cyclobutane Structures Fused to a 13‐Membered Ring.
Authors: YAMAGUCHI K. , TAKEDA K. , SHIMOTANI A. , YOSHII E. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arenediazonium Salts: New Probes of the Interfacial Compositions of Association Colloids. Part 1. Basic Approach, Methods, and Illustrative Applications.
Authors: CHAUDHURI A. , LOUGHLIN J. A. , ROMSTED L. S. , YAO J. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Dihydroxylation (AD)/Cyclization of N‐DiBoc Allylic and Homoallylic Amines: Selective Differentiation of the Hydroxyl Groups.
Authors: WALSH P. J. , BENNANI Y. L. , SHARPLESS K. B. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Double Diastereoselection in Asymmetric Dihydroxylation.
Authors: MORIKAWA K. , SHARPLESS K. B. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stabilizing Effect by Geminal Dioxy Substitution and Anomeric Effect in 3,6‐Dihydro‐6‐methoxy‐1,2‐oxathiin 2‐Oxides.
Authors: DEGUIN B. , VOGEL P. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convergent Route to Calcitriol Lactone via Reductive Cleavage of an Enantiopure Glycidyl Ether.
Authors: CONROW R. E. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 4‐Ethoxymethylene‐2‐phenyl‐5(4H)‐oxazolone as a Synthon for the Synthesis of Some Fused Pyrimidines.
Authors: KEPE V. , KOCEVAR M. , POLANC S. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Steric and Electronic Effects Controlling the Synthesis of Bridgehead Nitrogen Heterocycles.
Authors: DESTEVENS G. , EAGER M. , TARBY C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Versatile Synthetic Route to 1‐Benzometalloles Involving the First Examples of Several C‐Unsubstituted Benzometalloles.
Authors: KURITA J. , ISHII M. , YASUIKE S. , TSUCHIYA T. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalysis of Hydrosilylation. Part 22. Polymer‐Protected Immobilized Platinum Complex Catalysts for Gas‐Phase Hydrosilylation of Acetylene.
Authors: MARCINIEC B. , FOLTYNOWICZ Z. , LEWANDOWSKI M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tris(trimethylsilyl)silane in the Alkylation of Heteroaromatic Bases with Alkyl Halides.
Authors: TOGO H. , HAYASHI K. , YOKOYAMA M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple and Efficient Palladium‐Catalyzed Carbonylation of Iodoxyarenes in Water Under Mild Conditions.
Authors: GRUSHIN V. V. , ALPER H. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: η2‐Pyrrole Complexes as Synthons to Alkaloid Derivatives.
Authors: HODGES L. M. , GONZALEZ J. , KOONTZ J. I. , MYERS W. H. , HARMAN W. D. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (2‐Chlorovinyl)chlorocarbenes: Generation and Reactions with Olefins.
Authors: SHAVRIN K. N. , OKONNISHNIKOVA G. P. , NEFEDOV O. M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: S‐Tosylsulfenamides ‐ New Electrophilic Reagents for the Sulfo‐ Sulfenylation Reaction.
Authors: ZEFIROV N. S. , ZYK N. V. , KUTATELADZE A. G. , BELOGLAZKINA E. K. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Dibenzotrisdehydro(16)annulene‐1,4‐dione and the Related Compounds.
Authors: HIGUCHI H. , YAMAMOTO H. , OJIMA J. , YAMAMOTO G. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective Electrosynthesis of (CH3)2C60: A Novel Method for the Controlled Functionalization of Fullerenes.
Authors: CARON C. , SUBRAMANIAN R. , D'SOUZA F. , KIM J. , KUTNER W. , JONES M. T. , KADISH K. M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Simple, Inexpensive Synthesis of Oxiranes from Carbonyl Compounds. Generation of Sulfonium Ylides from the Ternary System Methanol‐ Sulfuric Acid‐Dimethyl Sulfide.
Authors: FORRESTER J. , JONES R. V. H. , PRESTON P. N. , SIMPSON E. S. C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐(Tributylstannyl)‐1‐((2‐(trimethylsilyl)ethoxy)methyl)‐1H‐indole: Synthesis and Use as a 1H‐Indol‐2‐yl‐Anion Equivalent.
Authors: PALMISANO G. , SANTAGOSTINO M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Infrared Spectra, Conformation, and Antiyeast Activity of 2‐ (Alkoxycarbonylmethylthio)‐6‐aminobenzothiazoles.
Authors: SIDOOVA E. , PERJESSY A. , LOOS D. , KUCHTA T. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5‐Oxo‐5,6,7,8‐tetrahydroquinolinium Salts: Synthesis and Reactions.
Authors: ZANDERSONS A. , SHKIL G. P. , LUSIS V. , MUCENIECE D. , SAGITULLIN R. S. , DUBURS G. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fused Pyrimidines. Part 5. Pyrimido(4,5‐d)pyrimidine Analogues of Folic Acid.
Authors: DELIA T. J. , BAUMANN M. , BUNKER A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Formation of (7)(2,6)Pyridinophanes by Ring Enlargement of a Pyrido(1, 2‐a)azepinone.
Authors: MAIER W. , KELLER M. , EBERBACH W. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Cryptands Having Tritopic Receptor Sites by (2 + 3)Schiff Base Condensation Using Cs(I) Ion as the Template.
Authors: RAGUNATHAN K. G. , SHUKLA R. , MISHRA S. , BHARADWAJ P. K. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.