bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical outcomes of drug‐eluting versus bare‐metal in‐stent restenosis
Authors: Singh Inder M. , Filby Steven J. , Sakr Fredy El , Gorodeski Eiran Z. , Lincoff A. Michael , Ellis Stephen G. , Shishehbor Mehdi H. 
Published: September 2009

AbstractIn‐stent restenosis (ISR) is a challenging syndrome that affects drug‐eluting stents and bare‐metal stents. However, data comparing the outcomes of drug‐eluting versus bare‐metal ISR are limited. Our objective was to evaluate the long‐term clinical outcomes of drug‐eluting versus bare‐metal ISR. Patients who underwent percutaneous coronary intervention at Cleveland Clinic for ISR from 05/1999 to 06/2007 were included. Unadjusted outcomes were tested using Kaplan‐Meier curves followed by multivariable adjusted Cox proportional hazards analyses. Twenty seven variables, including type of stent used to treat ISR and procedural date, were included. The primary end point was a composite of death, myocardial infarction (MI), or target lesion revascularization (TLR). The secondary endpoints were components of the primary endpoint. Of 931 patients identified, 225 had drug‐eluting ISR and 706 had bare‐metal ISR. There were 279 cumulative events for a median follow‐up of 3.2 years. The primary endpoint was not different between drug eluting and bare‐metal ISR (22% versus 33%, adjusted hazard ratio [HR] 1.14; 95% confidence interval [CI], 0.79–1.66; P = 0.49). The secondary endpoints of death (8% versus 16%, adjusted HR 1.05; 95% CI, 0.56–1.98; P = 0.88), MI (4% versus 5%, adjusted HR 1.48; 95% CI, 0.54–4.04; P = 0.45), and TLR (15% versus 16%, adjusted HR 1.30; 95% CI, 0.81–2.11; P = 0.28) were also not different. This study represents the largest analysis comparing drug‐eluting to bare‐metal ISR. On multivariable Cox proportional hazard analyses, drug‐eluting and bare‐metal ISR have similar long term outcomes. © 2009 Wiley‐Liss, Inc.
Current balloon‐expandable transcatheter heart valve and delivery systems
Authors: Nietlispach Fabian , Wijesinghe Namal , Wood David , Carere Ronald G. , Webb John G. 
Published: September 2009

AbstractObjectives: Transcatheter valve and valve delivery systems are undergoing rapid evolution. We describe the current generation balloon‐expandable valve and delivery systems. Background and Methods: The SAPIEN XT valve represents the newest generation balloon‐expandable aortic bioprosthesis. A cobalt‐chromium alloy frame and additional design modifications facilitate a reduction in delivery profile while maintaining structural integrity, hemodynamics, and durability. The RetroFlex 3™ delivery system represents the latest clinically available delivery system. It incorporates a fixed, tapered, and deflecting crossing tip to facilitate atraumatic introduction and a rapid inflation lumen to reduce valve motion during deployment. The NovaFlex™ delivery system represents the next generation delivery catheter. When used in conjunction with the SAPIEN XT™ valve and a specially constructed introducer sheath the inner and the outer diameters are 18 and 21 F, respectively. Results: The RetroFlex 3 delivery system was utilized in nine patients and the NovaFlex delivery system in four. The valve implanted was the SAPIEN in six and the SAPIEN XT valve in seven. Implantation was successful in all patients. A reduction in device movement during balloon deployment was apparent as compared with earlier delivery systems. Aortic mean gradient fell from 45.6 (±15.1) mm Hg to 13.2 (±5.1) mm Hg, valve area rose from 0.68 (±0.19) to 1.5 (±0.28) cm2. No patient had more than mild paravalvular regurgitation. Conclusion: Transcatheter valves and delivery systems continue to improve in terms of profile and ease of use. © 2009 Wiley‐Liss, Inc.
Coarctation of the aorta treated with the Advanta V12 large diameter stent: Acute results
Authors: Bruckheimer Elchanan , Birk Einat , Santiago Raul , Dagan Tamir , Esteves Carlos , Pedra Carlos A.C. 
Published: September 2009

AbstractObjectives: To report on the early results of treatment of coarctation of the aorta by dilation with a new polytetrafluoroethylene covered stent. Background: Transcatheter dilation of aortic coarctation carries the risk of aneurysm or rupture. Covered stent implantation reduces this risk but requires a large delivery system. The Advanta V12 LD covered stent is premounted and requires a 9–11 Fr delivery system. Methods: Covered stents on balloons of a diameter sufficient to anchor the stent in the coarctation were implanted using the smallest available delivery system. Secondary dilation with larger diameter balloons was performed until the pressure gradient was <20 mm Hg and the stent was opposed to the aortic wall. Results: Twenty‐five patients with aortic coarctation underwent stent implantation. Coarctation diameter increased from (6.3 ± 3.5) mm to (14.4 ± 2.3) mm (P < 0.0001). Peak pressure gradient decreased from (25.3 ± 11.6) mm Hg to (2.5 ± 3.0) mm Hg (P < 0.0001). The stent achieved the desired diameter in all cases. There were no complications. At short‐term median follow‐up of 4.9 months, all patients are alive and well with no evidence of recoarctation or aneurysm. Conclusions: These initial results show that the covered Advanta V12LD stent is safe and effective in the immediate treatment of coarctation of the aorta through a low profile delivery system of 8–11 Fr. Long term follow up is required. © 2009 Wiley‐Liss, Inc.
Transcatheter closure of perimembranous ventricular septal defects using a novel wire‐maintaining technique
Authors: Gu Ming‐Biao , You Xiao‐Hua , Zhao Xian‐Xian , Zheng Xing , Li Wei‐Ping , Qin Yong‐Wen 
Published: September 2009

AbstractObjectives: We aimed to evaluate the clinical feasibility and safety of a novel wire‐maintaining technique (WMT) for transcatheter closure of perimembranous ventricular septal defects (PmVSDs). Background: Transcatheter device closure of PmVSDs has been increasingly performed and this procedure is now offered as primary therapy at many institutions. Methods: A total of 103 patients with complex PmVSDs were randomized to either the conventional technique (CT) group (n = 51) or the WMT group (n = 52). In the CT group, the track wire was withdrawn before the occluder insertion and deployment. If inappropriate, the initial occluder was withdrawn and the “arteriovenous wire loop” was re‐established. In the WMT group, the track wire was maintained in the delivery sheath during the procedure. If the initial occluder was inappropriate, the delivery sheath could be reintroduced over the maintained wire. Results: For those patients who could not achieve optimal results with the initially selected occluders and required further device replacement, the procedure and fluoroscope time was reduced significantly in the WMT group compared with the CT group ([50.8 ± 13.2] min vs. [61.5 ± 15.4] min, P < 0.01 and [21.6 ± 8.6] min vs. [27.3 ± 7.4] min, P < 0.05; respectively). There was no difference in the incidence of complications of two groups. Conclusions: The WMT was feasible and safe for the transcatheter treatment of PmVSDs, especially for those complex defects with great challenge. Using this novel technique, the reconstruction of “arteriovenous wire loop” could be avoided in patients requiring device replacement. © 2009 Wiley‐Liss, Inc.
Indications and clinical outcomes for below knee endovascular therapy: Review article
Authors: Graziani Lanfroi , Piaggesi Alberto 
Published: September 2009

AbstractChronic critical limb ischemia (CLI) still represents the most common cause for amputation and frequently the possibility for peripheral revascularization, particularly in below knee (BK) arteries, is not adequately evaluated before amputation. This may also be due to the fact that even today, there's some confusion about results of the endovascular treatment in this territory. Diabetics, representing the population most frequently affected by CLI, have specific clinical characteristics, the so called diabetic foot syndrome, which cannot be compared with the situation in nondiabetic patients with ischemic ulcers. Measuring the success of BK endovascular therapy can be a difficult issue, considering that it is often the work of a multidisciplinary team. The clinical benefit of BK endovascular therapy often shows a large discrepancy from the primary patency. While ulcer healing, limb salvage, and reintervention rates are usually low after BK endovascular therapy, rates of restenosis remain excessively high. Nevertheless, the positive impact of revascularization on mortality, which mainly depends on the major amputation rate reduction, is also evident. This review article summarizes indications and clinical outcomes after BK endovascular therapy with special attention to the role of diabetes mellitus in patients with CLI. © 2009 Wiley‐Liss, Inc.
Intramolecular Spin Alignment within Mono‐Oxidized and Photoexcited Anthracene‐Based π Radicals as Prototypical Photomagnetic Molecular Devices: Relationships Between Electrochemical, Photophysical, and Photochemical Control Pathways
Authors: Matsumoto Isao , Ciofini Ilaria , Lainé Philippe P. , Teki Yoshio 
Published: September 2009

AbstractAnOV is a π‐conjugated radical built from an anthracene (An) unit linked by a p‐phenylene to an oxoverdazyl (OV) moiety. The mono‐oxidized (cationic) form of AnOV was generated both electrochemically and photochemically (in the presence of an electron acceptor). The triplet nature (S=1) of the electronic ground state of AnOV+ was demonstrated by combining spectroelectrochemistry, electron‐spin resonance (ESR) experiments, and ab initio molecular orbital (MO) calculations. The intramolecular spin alignment (ISA) within AnOV+ results from the ferromagnetic coupling (Jelectrochem>0) of the two unpaired electrons located on the oxidized electron donor (An+) and on the pendant OV radical. The spin‐density distribution pattern of AnOV+ is akin to that of AnOV when photopromoted (AnOV*) to its high‐spin (HS) lowest excited quartet (S=3/2) state. This high‐spin state results from the ferromagnetic coupling (Jphotophys>0) of the triplet locally excited state of An (3An*) with the doublet ground state of OV. As a shared salient feature, AnOV+ and AnOV* (HS) show a spin delocalization within the domain of activated An in either An+ or 3An* (nexus states) forms. The present study essentially contributes to establish and clarify relationships between electrochemical, photophysical, and photochemical pathways to achieve ISA processes within AnOV. In particular, we discuss the impact of the spin polarization of the unpaired electron of OV on electronic features of the An electron‐donating subunit. Close analysis of this polarizing interplay allows one to derive a novel functional paradigm to manipulate electron spins at the intramolecular level with light and under an external magnetic field. Indeed, two original functional elements are identified: light‐triggered donors of spin‐polarized electrons and spin‐selective electron acceptors, which are of potential interest for molecular spintronics.
Reducing GaH and GaC Bonds in Close Proximity to Oxidizing Peroxo Groups: Conflicting Properties in Single Molecules
Authors: Uhl Werner , Reza Halvagar Mohammad , Claesener Michael 
Published: September 2009

AbstractTreatment of [Li(H2Ga{CH(SiMe3)2}2)]⋅2 OEt2 (1⋅2 OEt2) with two equivalents of tert‐butyl hydrogen peroxide, H‐O‐O‐CMe3, afforded the organogallium peroxide [({(Me3Si)2HC}2Ga(OH)(OOCMe3)Li)2] (3), which possesses oxidizing peroxo groups in close proximity to reducing GaC bonds. The lithium atoms of the dimeric formula units are coordinated by both oxygen atoms of the peroxides and by two hydroxo groups. The cleavage of the GaC bond was not observed, even when an excess of H‐O‐O‐CMe3 was applied. Instead, the adduct [{(Me3Si)2HC}2Ga(OH)(OOCMe3)2Li2(HOOCMe3)] (4) was isolated, which has an intact H‐O‐O‐CMe3 molecule terminally attached to lithium. A similar structural motif was found for the compound [(LiOOCMe3)2(HOOCMe3)2] (5). The trihydrido gallanate [Li(H3Ga{CH(SiMe3)2})]⋅OEt2 (2) yielded the unique peroxide [({(Me3Si)2HC}Ga(H)(OOCMe3)2Li)2] (6) under similar conditions that possesses GaC and even more reactive GaH bonds beside peroxo groups. It decomposed at room temperature by the insertion of oxygen atoms into the GaH bonds and the formation of [({(Me3Si)2HC}Ga(OH)(OCMe3)(OOCMe3)Li)2] (7), which was isolated in a low yield. Further decomposition gave the complete degradation of all peroxo groups with the formation of a relatively complicated Li4Ga4O8 cage (8).
Enantiopure Aminopyrans by a Lewis Acid Promoted Rearrangement of 1,2‐Oxazines: Versatile Building Blocks for Oligosaccharide and Sugar Amino Acid Mimetics
Authors: Al‐Harrasi Ahmed , Pfrengle Fabian , Prisyazhnyuk Vladimir , Yekta Shahla , Koóš Peter , Reissig Hans‐Ulrich 
Published: September 2009

Abstract1,3‐Dioxolanyl‐substituted 1,2‐oxazines, such as syn‐1 and anti‐1, rearrange under Lewis acidic conditions to provide bicyclic products 2–5. Subsequent reductive transformations afforded enantiopure 3‐aminopyran derivatives such as 7 and 9 or their protected diastereomers 16 and 18, which can be regarded as carbohydrate mimetics. An alternative sequence of transformations including selective oxidation of the primary hydroxyl groups in 21 and 24 led to two protected β‐amino acid derivatives with carbohydrate‐like backbone (sugar amino acids). Treatment of bicyclic ester 23 with samarium diiodide cleaved the NO bond and furnished the unusual β‐lactam 27 in excellent yield. Alternatively, γ‐amino acid derivative 29 was efficiently prepared in a few steps. Fairly simple transformations gave azides 32 and 35 or alkyne 30 which are suitable substrates for the construction of oligosaccharide mimetics such as 34 by copper iodide catalyzed cycloadditions. With this report we demonstrate that enantiopure rearrangement products 2–5 are protected precursors of a variety of polyfunctionalized pyran derivatives with great potential for chemical biology.
Acid‐Catalyzed Cyclization of Terpenes Under Homogeneous and Heterogeneous Conditions as Probed Through Stereoisotopic Studies: A Concerted Process with Competing Preorganized Chair and Boat Transition States
Authors: Raptis Christos , Lykakis Ioannis N. , Tsangarakis Constantinos , Stratakis Manolis 
Published: September 2009

AbstractBased on stereoisotopic studies and β‐secondary isotope effects, we propose that the acid‐catalyzed cyclization of geranyl acetate proceeds through a concerted mechanism. Under heterogeneous conditions (zeolite Y confinement), a preorganized chairlike transition state predominates, whereas under homogeneous conditions the boat‐ and chairlike transition states are almost isoenergetic. For the case of farnesyl acetate, we propose that under homogeneous conditions a concerted dicyclization occurs with a preorganized boat–chair transition state competing with the chair–chair transition state. Under zeolite confinement conditions, the chair–chairlike dicyclization transition state is highly favorable. The preference of chairlike transition states within the cavities of zeolite Y is attributed to a transition state shape selectivity effect.
Soft‐Chemical Exfoliation Route to Layered Cobalt Oxide Monolayers and Its Application for Film Deposition and Nanoparticle Synthesis
Authors: Kim Tae Woo , Oh Eun‐Jin , Jee Ah‐Young , Lim Seung Tae , Park Dae Hoon , Lee Minyung , Hyun Sang‐Hoon , Choy Jin‐Ho , Hwang Seong‐Ju 
Published: September 2009

AbstractA colloidal suspension of exfoliated, layered cobalt oxide nanosheets has been synthesized through the intercalation of quaternary tetramethylammonium ions into protonated lithium cobalt oxide. According to atomic force microscopy, exfoliated nanosheets of layered cobalt oxide show a plateau‐like height profile with nanometer‐level height, underscoring the formation of unilamellar 2D nanosheets. The exfoliation of layered cobalt oxide was cross‐confirmed by X‐ray diffraction, UV/Vis spectroscopy, and transmission electron microscopy. The maintenance of the hexagonal in‐plane structure of the cobalt oxide lattice after the exfoliation process was evidenced by selected‐area electron diffraction and Co K‐edge X‐ray absorption near‐edge structure analysis. The zeta‐potential measurements clearly demonstrated the negative surface charge of cobalt oxide nanosheets. Adopting the nanosheets of layered cobalt oxide as a precursor, we were able to prepare the monodisperse CoO nanocrystals with a particle size of ≈10 nm as well as the heterolayered film composed of cobalt oxide monolayer and polycation.
ChemInform Abstract: Hydrated Alkali Metal and Ammonium Salts of the [P2Se6]4‐ Anion.
Authors: Rothenberger Alexander , Malliakas Christos D. , Kanatzidis Mercouri G. 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Variant of Highly Symmetric Layered Perovskite with Coordinated NO3‐ Ligand: Hydrothermal Synthesis, Structure, and Characterization of Cs2PbCl2(NO3)2.
Authors: Kim Min Kyung , Jo Vinna , Ok Kang Min 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: BaNbO(IO3)5: A New Polar Material with a Very Large SHG Response.
Authors: Sun Chuan‐Fu , Hu Chun‐Li , Xu Xiang , Ling Ji‐Bei , Hu Ting , Kong Fang , Long Xi‐Fa , Mao Jiang‐Gao 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural, Photophysical and Photocatalytic Properties of New Bi2SbVO7 under Visible Light Irradiation.
Authors: Luan Jingfei , Pan Bingcai , Paz Yaron , Li Yongmei , Wu Xiaoshan , Zou Zhigang 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bi3Mn3O11: A New KSbO3‐Type Random Ferrimagnet with High TC.
Authors: Belik Alexei A. , Takayama‐Muromachi Eiji 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantiospecific Synthesis and Allylation of All‐Carbon‐Substituted α‐Chiral Allylic Stannanes.
Authors: Schmidtmann Eric S. , Oestreich Martin 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: TfNH2 as Achiral Hydrogen‐Bond Donor Additive to Enhance the Selectivity of a Transition Metal Catalyzed Reaction. Highly Enantio‐ and Diastereoselective Rhodium‐Catalyzed Cyclopropanation of Alkenes Using α‐Cyano Diazoacetamide.
Authors: Marcoux David , Azzi Soula , Charette Andre B. 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ionic Liquid Promoted Regio‐ and Stereoselective Addition of Thiols to Alkynes and Alkenes under Organic Solvent‐Free Condition — A Green Reaction.
Authors: Ranu Brindaban C. , Chattopadhyay Kalicharan , Ghosh Sudip , Jana Ranjan 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Knoevenagel Condensation Catalyzed by 2‐Hydroxyethylammonium Acetate under Solvent‐Free Conditions at Room Temperature.
Authors: Zhou Zhongqiang , Yuan Jiangyong , Yang Rong 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Step Direct Conversion of Heterocyclic Aldehydes to Esters.
Authors: Goswami Shyamaprosad , Hazra Anita 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nickel‐Catalyzed Formation of a Carbon—Nitrogen Bond at the β Position of Saturated Ketones.
Authors: Ueno Satoshi , Shimizu Ryosuke , Kuwano Ryoichi 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile and Efficient Enantioselective Strecker Reaction of Ketimines by Chiral Sodium Phosphate.
Authors: Shen Ke , Liu Xiaohua , Cai Yunfei , Lin Lili , Feng Xiaoming 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reductive Amine Deallyl‐ and Debenzylation with Alkali Metal in Silica Gel (M‐SG).
Authors: Nandi Partha , Dye James L. , Jackson James E. 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild Copper‐Mediated Glaser‐Type Coupling Reaction under the Novel CuI/NBS/DIPEA Promoting System.
Authors: Li Lingjun , Wang Jiuxia , Zhang Guisheng , Liu Qingfeng 
Published: September 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.