bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal and hydrodynamic characteristics of constructal tree‐shaped minichannel heat sink
Authors: Chen Yongping , Zhang Chengbin , Shi Mingheng , Yang Yingchun 
Published: December 2009

AbstractA three‐dimensional thermal and hydrodynamic model for constructal tree‐shaped minichannel heat sink is developed. The heat and fluid flow in the constructal heat sink with an inlet hydraulic diameter of 4 mm are numerically analyzed, taking into consideration conjugate heat transfer in the channel walls. The pressure drop, temperature uniformity, and coefficient of performance (COP) of the constructal tree‐shaped heat sink are evaluated and compared with those of the corresponding traditional serpentine flow pattern. The results indicate that the constructal tree‐shaped minichannel heat sinks have considerable advantages over the traditional serpentine flow patterns in both heat transfer and pressure drop. The strong and weak heat flow can be effectively allocated in tree‐shaped flow structures; hence, the inherent advantage of uniform temperature on the heating surface in the constructal tree‐shaped heat sink is demonstrated. And in tree‐shaped flow structures, the local pressure loss due to confluence flow is found to be larger than that due to diffluence flow. In addition, an aluminum constructal tree‐shaped minichannel heat sink is fabricated to conduct the verification experiment. The experimentally measured temperature distribution and pressure drop are in agreement with the numerical simulation, which verifies that the present model is reasonable. © 2009 American Institute of Chemical Engineers AIChE J, 2010
Investigation on the melt spinning fibers of PP/organoclay nanocomposites prepared by in‐situ polymerization
Authors: Hao Chaowei , Zhao Ying , He Aihua , Zhang Xiuqin , Wang Dujin , Ma Qingfang , Xu Yizhuang 
Published: January 2010

AbstractFibers prepared by melt spinning process from the PP (polypropylene)/organoclay nanocomposite were characterized in details with the aid of SEM, FTIR, XRD, DSC, and mechanical measurements. The results suggested that the lower content of organoclay (0.1%) added to the PP matrix increased the crystallinity and mechanical property (tensile strength) of the PP/organoclay nanocomposite fiber. With increasing the content of organoclay (≥ 0.3%), the crystallinity and the tensile strength both a little decreased, and the fiber containing organoclay exhibited multi‐peaks at the same draw ratio during the heating process. Furthermore, the degree of orientation of the fiber increased a little with lower content of organoclay (0.1%) introduction to PP during the infrared dichroism measurement. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Novel 2,4‐divinyl‐3‐alkylthiophene/1,3,4‐oxadiazole alternating conjugated copolymer synthesized by the Heck coupling method: Synthesis, characterization, and electronic and optical properties
Authors: Qi Zheng‐Jian , Wei Bin , Shi Chen , He Yan‐Fang , Yu Jing , Wang Xue‐Mei , Kang Feng , Jin Biao , Sun Yue‐Ming 
Published: January 2010

AbstractA novel alternating copolymer with 3‐alkylthiophene and oxadiazole (or pyridine) units in ordered arrangement was synthesized with vinyl as a bridge for the first time. The synthesis process included four steps: bromomethylation, preparation of the ylide monomer, the formation of 2,4‐divinyl‐3‐alkylthiophene, and Heck alternating copolymerization. The Fourier transform infrared spectroscopy, 1H‐NMR, and gel permeation chromatography measurements showed that all of the copolymers had the required structures. The weight‐average molecular weights of the copolymers were in the range 5500–15,000 with a relatively low polydispersity index of 1.4–1.7. The solubility of the copolymers in common solvents (e.g., methylene chloride, chloroform, tetrahydrofuran) was excellent. The optical properties and bandgap of the copolymers was compared with corresponding poly(3‐alkylthiophene) homopolymers. The photoluminescence quantum efficiency (QE) of the copolymers improved markedly in chloroform. The QEs of poly(2,4‐divinyl‐3‐hexylthiophene‐alt‐2,5‐diphenyl‐1,3,4‐ oxadiazole) and poly(2,4‐divinyl‐3‐octythiophene‐alt‐2,5‐diphenyl‐1,3,4‐oxadiazole) were 43.2 and 34.2%, respectively, which were about 20 and 21 times higher than those of the homopolymers, respectively. The ionization potential of the copolymers between 5.53 and 6.13 eV was appropriated to poly(3‐alkylthiophene)s. The high electron affinity of the copolymers (2.71–2.95 eV) made the electrons inject from the cathode more easily. With excellent solubility, low bandgap energy, high QE, and both electron‐transporting and hole‐transporting abilities, the proposed copolymers might be excellent polymeric materials for applications in polymer light‐emitting diodes, light‐emitting electrochemical cells, and polymer solar cells. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Synthesis and properties of novel poly(coumarin‐amide)s
Authors: Nechifor Marioara 
Published: January 2010

AbstractA novel monomer diacid, 6,6′‐methylenebis(2‐oxo‐2H‐chromene‐3‐carboxylic acid), was synthesized and used in a direct polycondensation reaction with various aromatic diamines in N‐methyl‐2‐pyrrolidone solution containing dissolved LiCl and CaCl2, using triphenyl phosphite and pyridine as condensing agents to give a series of novel heteroaromatic polyamides containing photosensitive coumarin groups in the main chain. Polyamide properties were investigated by DSC, TGA, GPC, wide‐angle X‐ray scattering, viscosity, and solubility measurements. The copolymers were soluble in aprotic polar solvents, and their inherent viscosities varied between 0.49 and 0.78 dL g−1. The weight‐average and number‐average molecular weights, measured by gel permeation chromatography, were 27,500–43,900 g mol−1 and 46,500–66,300 g mol−1, respectively, and polydispersities in the range of 1.48–1.69. The aromatic polyamides showed glass‐transition temperatures (Tg) ranging from 283 to 329°C and good thermal properties evidenced by no significant weight loss up to 380°C and 10% weight loss recorded above 425°C in air. All the polyamides exhibited an amorphous nature as evidenced by wide‐angle X‐ray diffraction and demonstrated a film forming capability. Water uptake values up to 3.35% were observed at 65% relative humidity. These polymers exhibited strong UV‐vis absorption maxima at 357–369 nm in DMSO solution, and no discernible photoluminescence maxima were detected by exciting with 365 nm. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Study on the interfacial properties of three‐dimensionally arranged glass fiber/epoxy resin model composites
Authors: Moon C. K. 
Published: January 2010

AbstractThe effect of interfiber distance on the interfacial properties in three‐dimensional multi‐E‐glass fiber/epoxy resin composites has been investigated using fragmentation test. In additions, the effect of the fiber surface treatment on the interfacial properties has been studied. The interfacial shear strength decreased with the decreasing the interfiber distance at the range of under 50 μm and the extent of the decreasing was more serious as the increasing of the number of adjacent fiber. This is probably due to the fact that the interface between the fiber and the resin was damaged by the adjacent fiber breaks and the damage increased with closing the interfiber spacing and the number of adjacent fiber. It was found that the interfacial shear strengths saturated when the interfiber distance was over 50 μm, the ones were saturated regardless of fiber surface treatment and the ones were in close agreement with those of the single fiber fragmentation test. Finally, the interfacial shear strength evaluated using three‐dimensional fragmentation tests are shown as real values in‐site regardless of fiber surface treatment, interfiber distance and existing of matrix cracks. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Characterization of molecularly imprinted and nonimprinted polymer submicron particles specifically tailored for removal of trace 17β‐estradiol in water treatment
Authors: Lai Edward P. C. , Maleki Zack De , Wu Shuyi 
Published: January 2010

AbstractThis study investigated the potential use of molecularly imprinted polymer (MIP) submicron particles for the selective removal of trace 17β‐estradiol (E2) in water treatment. Methacrylate‐based MIP submicron particles were synthesized, in a one‐step suspension polymerization procedure, using ethylene glycol dimethacrylate (EGDMA) as the cross‐linker. After template removal, the particles could be used as a smart material for specific binding of E2. The submicron size of MIP particles facilitated uniform dispersion in water for up to 17 days. These particles were meritorious in mass transfer behavior, allowing phase partitioning of E2 molecules in water during a short treatment time. After 1‐mL water samples of different E2 concentrations were treated with 20 mg of MIP particles for 2 min, recovery percentages as high as 97% ± 3% were achieved. The specific binding capacity of these MIP particles was determined to be 15 mg E2/g. Nonimprinted polymer nanoparticles were also evaluated for nonspecific binding of E2, using 0.5 mg in 1 mL of water, to attain 64% ± 3% efficiency in 3 min towards general water treatment. A simple capillary electrophoresis method was successfully developed for the characterization of MIP and NIP particles. Apparently the less negative the electrophoretic mobility, the higher binding efficiency and faster binding kinetics the particles would exhibit with E2 due to less hindered Brownian diffusion. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Effect of metallic flask closure and investment materials on the stability of the denture base resin
Authors: Consani Rafael Leonardo Xediek , Mesquita Marcelo Ferraz , Sobrinho Lourenço Correr , Sinhoreti Mario Alexandre Coelho 
Published: January 2010

AbstractThis study evaluated the dimensional stability of the poly‐methylmethacrylate (PMMA) denture bases under the effect of different metallic flask closure techniques (FCT) and investment materials (IM). Sixty stone cast maxillary‐wax base plate sets were randomly assigned to six groups (n = 10) for the following treatments: 1 and 4—stone or silicone investments and flask closure with clamp; 2 and 5—stone or silicone investments and flask closure with RS system; 3 and 6—stone or silicone investments and flask closure with screws. PMMA denture bases were polymerized in a water bath at 74°C for 9 h. PMMA base‐stone cast sets were sectioned at regions (R) of the canines, first molars, and posterior palatal zone. Gap discrepancies were measured at five points: right and left ridge crests, palatal midline, and right and left marginal limits of the flanges. An optical micrometer with accuracy of 0.0005 mm was used for measurement purposes. Data were submitted to ANOVA and Tukey's test (α = 0.05). Silicone showed an adaptation mean (0.177 mm) significantly different when compared with stone (0.207 mm). The RS system presented a statistically different adaptation mean (0.166 mm) in relation to the traditional clamp (0.200 mm) and flask with screws (0.211 mm). Adaptation values for the regions of the canines (0.141 mm), first molars (0.185 mm), and posterior palatal (0.250 mm) were statistically different. For all flask closure techniques, better adaptation was shown with the RS system and silicone investment. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Making sense of archived e‐mail: Exploring the Enron collection with NetLens
Authors: Kang Hyunmo , Plaisant Catherine , Elsayed Tamer , Oard Douglas W. 
Published: December 2009

AbstractInformal communications media pose new challenges for information‐systems design, but the nature of informal interaction offers new opportunities as well. This paper describes NetLens‐E‐mail, a system designed to support exploration of the content‐actor network in large e‐mail collections. Unique features of NetLens‐E‐mail include close coupling of orientation, specification, restriction, and expansion, and introduction and incorporation of a novel capability for iterative projection between content and actor networks within the same collection. Scenarios are presented to illustrate the intended employment of NetLens‐E‐mail, and design walkthroughs with two domain experts provide an initial basis for assessment of the suitability of the design by scholars and analysts.
Fast membrane association is a crucial factor in the peptide pep‐1 translocation mechanism: A kinetic study followed by surface plasmon resonance
Authors: Henriques Sónia Troeira , Castanho Miguel A. R. B. , Pattenden Leonard Keith , Aguilar Marie‐Isabel 
Published: January 2010

AbstractThe use of peptide carriers, termed “cell‐penetrating peptides (CPPs)” has attracted much attention due to their potential for cellular delivery of hydrophilic molecules with pharmacological interest, overcoming the membrane barrier. These peptides are able to deliver attached cargos in a nontoxic manner, with the uptake mechanisms being either endosomally or physically driven. Pep‐1 is a CPP of particular interest, not only due to outstanding delivery rates but also because its mechanism of membrane translocation is exclusively physically driven which appears to be dependent on a very high affinity for the phospholipid bilayer in the cell membrane. In this study, pep‐1‐lipid interactions were further explored by characterization of the pep‐1‐lipid association/dissociation by surface plasmon resonance. Although a high affinity of pep‐1 for lipid bilayers was observed in all conditions tested, negatively charged phospholipids resulted in a larger peptide/lipid ratio. We also show that pep‐1‐membrane interaction is a fast process described by a multistep model initiated by peptide adsorption, primarily governed by electrostatic attractions, and followed by peptide insertion in the hydrophobic membrane core. In the context of a cell‐based process, the translocation of pep‐1 is a physical mechanism promoted by peptide primary amphipathicity and asymmetric properties of the membrane. This explains the high efficiency rates of pep‐1 when compared with other CPPs. © 2010 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 94: 314–322, 2010.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Technological progresses in monoclonal antibody production systems
Authors: Rodrigues Maria Elisa , Costa Ana Rita , Henriques Mariana , Azeredo Joana , Oliveira Rosário 
Published: December 2009

AbstractMonoclonal antibodies (mAbs) have become vitally important to modern medicine and are currently one of the major biopharmaceutical products in development. However, the high clinical dose requirements of mAbs demand a greater biomanufacturing capacity, leading to the development of new technologies for their large‐scale production, with mammalian cell culture dominating the scenario. Although some companies have tried to meet these demands by creating bioreactors of increased capacity, the optimization of cell culture productivity in normal bioreactors appears as a better strategy. This review describes the main technological progresses made with this intent, presenting the advantages and limitations of each production system, as well as suggestions for improvements. New and upgraded bioreactors have emerged both for adherent and suspension cell culture, with disposable reactors attracting increased interest in the last years. Furthermore, the strategies and technologies used to control culture parameters are in constant evolution, aiming at the on‐line multiparameter monitoring and considering now parameters not seen as relevant for process optimization in the past. All progresses being made have as primary goal the development of highly productive and economic mAb manufacturing processes that will allow the rapid introduction of the product in the biopharmaceutical market at more accessible prices. © 2010 American Institute of Chemical Engineers Biotechnol. Prog., 2010
Preparation of Biomolecule Microstructures and Microarrays by Thiol–ene Photoimmobilization
Authors: Weinrich Dirk , Köhn Maja , Jonkheijm Pascal , Westerlind Ulrika , Dehmelt Leif , Engelkamp Hans , Christianen Peter C. M. , Kuhlmann Jürgen , Maan Jan C. , Nüsse Dirk , Schröder Hendrik , Wacker Ron , Voges Edgar , Breinbauer Rolf , Kunz Horst , Niemeyer Christof M. , Waldmann Herbert 
Published: December 2009

AbstractA mild, fast and flexible method for photoimmobilization of biomolecules based on the light‐initiated thiol–ene reaction has been developed. After investigation and optimization of various surface materials, surface chemistries and reaction parameters, microstructures and microarrays of biotin, oligonucleotides, peptides, and MUC1 tandem repeat glycopeptides were prepared with this photoimmobilization method. Furthermore, MUC1 tandem repeat glycopeptide microarrays were successfully used to probe antibodies in mouse serum obtained from vaccinated mice. Dimensions of biomolecule microstructures were shown to be freely controllable through photolithographic techniques, and features down to 5 μm in size covering an area of up to 75×25 mm were created. Use of a confocal laser microscope with a UV laser as UV‐light source enabled further reduction of biotin feature size opening access to nanostructured biochips.
Glyco‐Scan: Varying Glycosylation in the Sequence of the Peptide Hormone PYY3‐36 and Its Effect on Receptor Selectivity
Authors: Pedersen Søren L. , Steentoft Catharina , Vrang Niels , Jensen Knud J. 
Published: January 2010

AbstractThe increasing prevalence of obesity worldwide calls for safe and highly efficacious satiety drugs. PYY3‐36 has been implicated in food intake regulation, and novel peptide analogues with high Y2 receptor‐subtype selectivity and potency have potential as drugs for the treatment of obesity. It has been hypothesized that PYY3‐36 associates with the plasma membrane prior to receptor activation such that the amphipathic α‐helix of PYY3‐36 possibly guides the C‐terminal pentapeptide into the correct conformation for receptor activation. Ala‐scans are used routinely to study the effect of individual amino acids in a given peptide sequence. Here we report the glyco‐scan of the peptide hormone PYY3‐36, in which hydroxyl side‐chain functionalities were glycosylated; in addition new glycosylation sites were introduced. An array of novel PYY3‐36 analogues with a glycan positioned in the water–membrane interface or in the N terminal were screened for Y‐receptor affinity and selectivity as well as metabolic stability. Interestingly, in contrast to the Y1 and Y4 receptors, the Y2 receptor readily accommodated glycosylations. Especially glycosylations in the α‐helical region of PYY3‐36 were favorable both in terms of Y‐receptor selectivity and endopeptidase resistance. We thus report several PYY3‐36 analogues with enhanced Y‐receptor selectivity. Our results can be used in the design of novel PYY analogues for the treatment of obesity. The glyco‐scan concept, as systematically demonstrated here, has the potential for a wider applicability.
Dual catheter technique for the treatment of severe coronary artery perforations
Authors: Ben‐Gal Yanai , Weisz Giora , Collins Michael B. , Genereux Philippe , Dangas George D. , Teirstein Paul S. , Singh Varinder P. , Rabbani LeRoy E. , Kodali Susheel K. , Sherman Warren , Leon Martin B. , Moses Jeffrey W. 
Published: January 2010

AbstractObjectives: To evaluate the outcome of patients with coronary perforations who were treated with the dual catheter approach. Background: Coronary artery perforation is a grave complication of percutaneous coronary intervention (PCI) with high mortality and morbidity. Treating a coronary artery perforation with two catheters through dual access enables a rapid delivery of covered stent or coils to the vessel, without losing control of the perforation site. Methods: We retrospectively reviewed all patients who had a severe coronary perforation during a PCI in our center, and compared outcomes of patients treated with the dual versus the traditional single guiding catheter approach. Results: Between April 2004 and October 2008, 13,466 PCI's were performed in Columbia University – New York Presbyterian Medical Center. There were 33 documented cases of coronary perforations during that period of time (0.245%), among these, 26 were angiographically severe (Ellis type 2 or 3 perforations). Eleven patients were treated acutely with a dual catheter technique whereas the other fifteen patients were treated using a single guiding catheter. In the dual catheter group one patient expired after emergent CABG (9.1%), and four patients underwent emergent paricardiocentesis (36.4%). In patients treated with single catheter, there were three deaths (20%), two surgical explorations (13.3%), eight emergent pericardiocenthesis (53.3%), and one event of severe anoxic brain damage (6.7%). Conclusion: The dual catheter technique is a relatively safe and reproducible approach to treat a PCI induced severe coronary artery perforation, and may improve outcome compared to historical series. © 2010 Wiley‐Liss, Inc.
Rejoinder to ‘Comments on a recently published paper “Some surprising properties of multivariate curve resolution‐alternating least squares (MCR‐ALS) algorithms”’
Authors: Rajkó Róbert 
Published: December 2009

AbstractThis rejoinder addresses comments recently published in this journal on the paper titled ‘Some surprising properties of multivariate curve resolution‐alternating least squares (MCR‐ALS) algorithms’. It is explained again that the revealed discrepancy of MCR‐ALS algorithms, i.e. the sub‐ and even the final solutions can be outside the range of the data matrix, does exist and this theoretical fact could not be refuted by Tauler. Copyright © 2009 John Wiley & Sons, Ltd.
ChemInform Abstract: Cu9Bi9S16Cl8 and Cu7.4Bi6S12Cl7 — Frameworks of Polyhedra with Dichalcogenide Bridges and Mobile Copper(I) Cations.
Authors: Heerwig Andreas , Ruck Michael 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Temperature Superconductivity in a Single Copper‐Oxygen Plane.
Authors: Logvenov G. , Gozar A. , Bozovic I. 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of LnF(HF)(BF4)2 (Ln: La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, and Dy), and Crystal Structures of LnF(HF)(BF4)2 (Ln: Pr, Nd) and La(BF4)3.
Authors: Mazej Zoran , Goreshnik Evgeny , Hironaka Kohei , Katayama Yasushi , Hagiwara Rika 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Stoichiometric LiNbO3 Nanopowder Through a Wet Chemical Method.
Authors: Yao Shuhua , Zheng Feifei , Liu Hong , Wang Jiyang , Zhang Huaijin , Yan Tao , Wu Jianbo , Xia Zongren , Qin Xiaoyong 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.