bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential impact of money growth on inflationary outcomes: evidence from emerging markets using panel NARDL approach
Authors: Shrawan Aakanksha , Dubey Amlendu 
Published: June 2024

PurposeThe study seeks evidence on the asymmetric effects of broad money growth on inflation in the short run and long run, in the context of emerging markets and developing economies (EMDEs).Design/methodology/approachUsing a panel dataset of 122 EMDEs (by distinguishing between inflation-targeting and non-inflation-targeting EMDEs), we employ the nonlinear counterpart of the autoregressive distributed lag framework, which provides evidence of asymmetric dynamics between money growth and inflation in EMDEs.FindingsIn consonance with the quantity theory of money, we find a long-run relationship between money growth and inflationary outcomes. We also find that the response of inflation is higher to a tightening episode in the monetary policy stance than to a loosening episode. The study also provides evidence that adopting the inflation targeting framework in EMDEs has led to a significant reduction in the inflation rates along with ensuring a higher magnitude of transmission from money supply growth to inflationary outcomes.Originality/valueTo the best of our knowledge, the present study is one of the first attempts to evaluate the differential impact of broad money growth on inflationary outcomes, using a panel dataset of EMDEs. As a result of inherent differences in the financial structures of EMDEs vis-à-vis advanced nations, there is an imperative need to assess the dynamics of pass-through from money supply to inflation to gain an understanding of the mechanism of monetary transmission in these economies.
Unveiling the influence of anthropomorphic chatbots on consumer behavioral intentions: evidence from China and Indonesia
Authors: Wei Yuling , Syahrivar Jhanghiz , Simay Attila Endre 
Published: June 2024

PurposeChatbots have been explored as a novel approach to enhancing consumer engagement by delivering more enjoyable, personalized services. This research aims to investigate the mechanism through which anthropomorphic elements of chatbots influence consumers' intentions to use the technology.Design/methodology/approachThis research introduces five key concepts framed through the “computers-are-social-actors” (CASA) paradigm: form realism (FR), behavioral realism (BR), cognitive trust (CT), entertainment (EM) and chatbot usage intention (CUI). An online questionnaire garnered 280 responses from China and 207 responses from Indonesia. Data collection employed a combination of purposive and snowball sampling techniques. This research utilized structural equation modeling through the analysis of moment structures (AMOS) 27 software to test the hypotheses.Findings(1) FR positively predicts CT and EM, (2) FR negatively predicts CUI, (3) BR positively predicts CT and EM, (4) BR positively predicts CUI and (5) Both CT and EM mediate the relationship between FR and CUI, as well as between BR and CUI.Originality/valueThis research enriches the current literature on interactive marketing by exploring how the anthropomorphic features of chatbots enhance consumers' intentions to use such technology. It pioneers the exploration of CT and EM as mediating factors in the relationship between chatbot anthropomorphism and consumer behavioral intention. Moreover, this research makes a methodological contribution by developing and validating new measurement scales for measuring chatbot anthropomorphic elements.
Could synovial fluid be a useful substrate for the forensic analysis of diatoms?
Authors: Tambuzzi Stefano , Gentile Guendalina , Bailo Paolo , Primavera Riccardo , Andreola Salvatore , Zoja Riccardo 
Published: June 2024

AbstractTo date, synovial fluid has not been the subject of targeted analysis as a possible substrate to search for the presence of diatoms in the forensic context of drowning. However, its unique characteristics of production and isolation from the external environment could make it suitable for this purpose, similar to what has already been demonstrated in the literature for vitreous humor. By considering this, synovial fluid was analyzed in a specific case that came to our attention, where the coexisting signs of polytrauma and drowning were documented during autopsy, demonstrating a period of vitality during immersion. After a thin smear of the supernatant was obtained from the centrifugation of the synovial fluid sample, diatoms were successfully detected, consistent with those found in other organs and the water of the canal. The detection of diatoms in the synovial fluid was an objective finding, but its generalizability is limited because this was a pilot application. However, in cases where death by drowning is suspected and the body has multiple areas breached by trauma, the technique of analyzing diatoms in the synovial fluid could have great potential. Therefore, it is appropriate to further explore this technique in order to obtain more forensic evidence in such a setting.
Consumer acceptance and sensory perception of roasted American‐European hybrid hazelnuts
Authors: Booth Megan , Fu Mengying , Peterson Devin G. 
Published: June 2024

AbstractInterspecific American‐European hazelnut (Corylus americana × C. avellana) hybrids are being developed for the Upper Midwest region of the United States, which have potential economic and ecological benefits. Currently, researchers are working on pre‐commercialization initiatives to create a local hazelnut industry. However, a lack of knowledge on the sensory characteristics and consumer acceptability of the hybrid hazelnuts have been identified as potential limitations to production. This study investigated consumer responses to hybrid hazelnuts, employing hedonic ratings and check‐all‐that‐apply (CATA) questions. Twelve roasted hazelnut hybrids were subjected to consumer evaluation for liking (aroma, color, flavor, texture, and overall) and aroma and flavor descriptors. Consumers also evaluated two European hazelnut varieties for comparative purposes. Liking scores were significantly different (p < 0.05) across different hybrid varieties and when comparing specific hybrids with European varieties. CATA sensory profiles specific to different varieties were also observed and discriminating attributes were identified using multiple‐response methodologies. Penalty analysis based on CATA further identified the attributes roasty, hazelnut‐like, caramel‐like, chocolate‐like, sweet, and salty as primary drivers of aroma/flavor liking, while earthy, burnt, and bitter were identified as primary drivers of disliking. Overall, unique flavors that impacted liking were found in hybrid hazelnuts and, when compared with European hazelnuts, provided insights for breeding and post‐processing strategies to optimize product quality.
Characteristics of pectens in diurnal and nocturnal birds and a new functional proposal relating to non‐visual opsins
Authors: Kusakabe Ken Takeshi , Seto Miho , Harada Yumiko , Kusakabe Asako , Yustinasari Lita Rakhma , Hyoto Muneyoshi , Nakahara Chihiro , Gondo Ai , Kondo Tomohiro , Kano Kiyoshi , Kiso Yasuo , Imai Hiroyuki 
Published: June 2024

AbstractThe pecten is a fold‐structured projection at the ocular fundus in bird eyes, showing morphological diversity between the diurnal and nocturnal species. However, its biological functions remain unclear. This study investigated the morphological and histological characteristics of pectens in wild birds. Additionally, the expression of non‐visual opsin genes was studied in chicken pectens. These genes, identified in the chicken retina and brain, perceive light periodicity regardless of visual communication. Similar pleat numbers have been detected among bird taxa; however, pecten size ratios in the ocular fundus showed noticeable differences between diurnal and nocturnal birds. The pectens in nocturnal brown hawk owl show extremely poor vessel distribution and diameters compared with that of diurnal species. RT‐PCR analysis confirmed the expression of Opn5L3, Opn4x, Rrh and Rgr genes. In situ hybridization analysis revealed the distribution of Rgr‐positive reactions in non‐melanotic cells around the pecten vessels. This study suggests a novel hypothesis that pectens develop dominantly in diurnal birds as light acceptors and contribute to continuous visual function or the onset of periodic behaviour.
Genome sequencing differentiates a paracentric inversion from a balanced insertion enabling more accurate preimplantation genetic testing
Authors: Wincent Josephine , Helgadóttir Hafdís T. , Sergouniotis Fotios , Salazar Mantero Angelo , Carvalho Claudia M. B. , Malmgren Helena , Lindstrand Anna , Iwarsson Erik 
Published: June 2024

AbstractIntroductionDistinguishing paracentric inversions (PAIs) from chromosomal insertions has traditionally relied on fluorescent in situ hybridization (FISH) techniques, but recent advancements in high‐throughput sequencing have enabled the use of genome sequencing for such differentiation. In this study, we present a 38‐year‐old male carrier of a paracentric inversion on chromosome 2q, inv (2)(q31.2q34), whose partner experienced recurrent miscarriages.Material and MethodsFISH analysis confirmed the inversion, and genome sequencing was employed for detailed characterization.ResultsPreimplantation genetic testing (PGT) revealed that all assessed embryos were balanced, consistent with the low risk of unbalanced offspring associated with PAIs. While PAI carriers traditionally exhibit low risk of producing unbalanced offspring, exceptions exist due to crossover events within the inversion loop. Although the sample size was limited, the findings align with existing sperm study data, supporting the rare occurrence of unbalanced progeny in PAI carriers.ConclusionsThis study highlights the possibility of characterizing PAIs using genome sequencing to enable correct reproductive counseling and PGT decisions. Detailed characterization of a PAI is crucial for understanding potential outcomes and guiding PGT strategies, as accurate knowledge of the inversion size is essential for appropriate method selection in PGT. Given the very low risk of unbalanced offspring in PAI carriers, routine PGT may not be warranted but should be considered in specific cases with a history of unbalanced progeny or recurrent miscarriages. This study contributes to our understanding of PAI segregation and its implications for reproductive outcomes.
Intensifying translocal precarity: The impact of COVID‐19 on smallholder farmers' commodity production and social reproduction in Cambodia
Authors: Yi Rosa , Green W. Nathan 
Published: June 2024

AbstractAgainst a backdrop of agrarian transformation, COVID‐19 intensified translocal precarity among smallholder farmers worldwide. As scholars of economic geography and agrarian studies have shown, smallholder households increasingly struggle to reproduce themselves through agrarian livelihoods alone, with many households compelled to migrate to urban centres, both domestic and foreign, to find employment. Consequently, smallholder farmers now experience precarity shaped by the translocal spaces of both production and social reproduction. In this paper, based on a qualitative study of smallholders in northwestern Cambodia conducted from 2019 to 2023, we argue that COVID‐19 deepened the translocal precarity of smallholder households, who already had to struggle with volatile commodity production and uncertain labour migration. We explain how the pandemic led to urban job losses and forced workers to return to rural homes and farming. On the farm, pandemic restrictions on cross‐border trade of agricultural inputs drove up production costs while competition for land between migrant returnees increased land rental fees, pushing many smallholders into debt traps following poor harvests. Indebted households responded by migrating to Thailand again, where labour demand for industrial production remained low after the pandemic, creating additional uncertainty about their migration journey. We conclude that the impacts of COVID‐19 on smallholder households are usefully explained through the lens of translocal precarity. This approach reveals how the pandemic played out within a broader conjuncture of agrarian transformation, defined by adverse incorporation into transnational commodity markets, a lack of sustaining infrastructure in the countryside, and an increasingly debt‐driven migration regime.
3D evaluation of sagittal inclination of the maxillary dentition in relation to facial landmarks: A cohort study
Authors: El‐Sabbagh Basel , Seidel Kathrin , Sayahpour Babak , Güth Jan‐Frederik 
Published: June 2024

AbstractBackgroundThe determination of the maxillary occlusal plane presents a significant clinical challenge in the treatment of edentulous patients as well as it is critical for complex full‐mouth reconstructions in dentate patients, including those with implant‐supported rehabilitations. While the use of a Fox plane plate is standard in edentulous cases, its application in dentate patients lacks thorough documentation in existing literature.PurposeThis clinical study assessed the sagittal position of the maxillary dentition in relation to facial landmarks using a digital three‐dimensional analysis and evaluated the suitability and reliability of applying a simulated Fox plane plate, also known as an occlusal plane guide, in dentate patients.Materials and MethodsEighty‐one subjects were recruited at the Department of Prosthetic Dentistry of Goethe University Frankfurt, Germany, according to specific inclusion criteria. Intraoral and facial scans were obtained and analyzed using GOM Inspect Pro software (GOM, Braunschweig, Germany). The angles between the maxillary occlusal plane and three variations each of Camper's plane and ala‐tragus line, relating to superior, middle, and inferior tragus points, were measured. These modified planes were then compared to a plane established by a simulated digital Fox plane plate, which was adapted to the maxillary anterior teeth and the lowest point of the posterior teeth in both quadrants.ResultsA total of 81 subjects (58 female and 23 male) with a mean age of 23.9 years were evaluated in this study. No significant angular difference was found between the angles of the maxillary occlusal plane compared with superior Camper's plane, middle Camper's plane, or superior ala‐tragus line (p >0.05). The smallest angle occurred between superior Camper's plane and the maxillary occlusal plane on both the right (3.443°) and left (3.535°) sides. The application of a Fox plane plate resulted in two different occlusal planes in 70% of patients, significantly deviating from the digitally determined plane (p <0.05).ConclusionSuperior and middle Camper's planes, along with superior ala‐tragus line, can be considered approximately parallel reference planes and are suitable for routine determining of the maxillary occlusal plane in restorative treatments. However, in contrast to digital evaluation methods, the application of a Fox plane plate in dentate patients showed high variability, indicating its low reproducibility due to its ambiguous positioning on the maxillary dentition.Clinical trial registration site: https://drks.de/search/de/trial/DRKS00030166.
Diagnostic pathway and management of first seizures in infants with Sturge–Weber syndrome
Authors: Mankel Finola Lauren , Papandreou Apostolos , Mankad Kshitij , Richardson Hanna , Aylett Sarah E. 
Published: June 2024

AbstractAimSturge–Weber syndrome (SWS) is a rare neurocutaneous syndrome, frequently associated with pharmaco‐resistant, early‐onset epilepsy. Optimal seizure control is paramount to maximize neurodevelopment.MethodA single‐centre case series of 49 infants explored early SWS care. Ninety‐two per cent of children developed seizures aged 0 to 3 years; 55% of cases were before diagnostic magnetic resonance imaging (MRI) or tertiary referral. Delay in SWS diagnosis affected 31% of infants because of a lack of gadolinium enhancement for initial MRI. First seizures were frequently prolonged, with phenytoin administration necessary in 46%. Presymptomatic antiseizure medication prophylaxis (n = 8/49) decreased seizure burden. No patients on antiseizure medication prophylaxis suffered status epilepticus for longer than 30 minutes, and half of them (n = 4) had not developed seizures at last follow‐up (aged 2–10 years).ResultsA parental survey enabled further service evaluation. Eighty‐three per cent of parents considered local clinicians' understanding of SWS inadequate: 61% felt insufficiently informed about SWS and 81% received no epilepsy education before seizures.InterpretationTo overcome the identified shortfalls, guidelines towards improving and standardizing SWS management are proposed.
Serum bile acid profiles are associated with heart failure with preserved ejection fraction in patients with metabolic dysfunction‐associated fatty liver disease: An exploratory study
Authors: Zhou Xiao‐Dong , Xu Cui‐Fang , Chen Qin‐Fen , Shapiro Michael D. , Lip Gregory Y. H. , Chen Li‐Li , Targher Giovanni , Byrne Christopher D. , Tian Na , Xiao Tie , Huang Chen‐Xiao , Ni Yan , Zheng Ming‐Hua 
Published: June 2024

AbstractAimTo analyse the association between serum bile acid (BA) profile and heart failure (HF) with preserved ejection fraction (HFpEF) in patients with metabolic dysfunction‐associated fatty liver disease (MAFLD).MethodsWe enrolled 163 individuals with biopsy‐proven MAFLD undergoing transthoracic echocardiography for any indication. HFpEF was defined as left ventricular ejection fraction >50% with at least one echocardiographic feature of HF (left ventricular diastolic dysfunction, abnormal left atrial size) and at least one HF sign or symptom. Serum levels of 38 BAs were analysed using ultra‐performance liquid chromatography coupled with tandem mass spectrometry.ResultsAmong the 163 patients enrolled (mean age 47.0 ± 12.8 years, 39.3% female), 52 (31.9%) and 43 (26.4%) met the HFpEF and pre‐HFpEF criteria, and 38 serum BAs were detected. Serum ursodeoxycholic acid (UDCA) and hyocholic acid (HCA) species were lower in patients with HFpEF and achieved statistical significance after correction for multiple comparisons. Furthermore, decreases in glycoursodeoxycholic acid and tauroursodeoxycholic acid were associated with HF status.ConclusionsIn this exploratory study, specific UDCA and HCA species were associated with HFpEF status in adults with biopsy‐confirmed MAFLD.
Reclaiming Agency in Care Decisions and Barriers From the Perspectives of Individuals With Acquired Brain Injury and Their Family Members
Authors: Ownsworth Tamara , Bates Annerley , Watter Kerrin , Morgan Clare , Bell Ryan , Griffin Janelle , Turner Ben , Kennedy Areti , Kendall Melissa , Adams Belinda , Gibson Emily , Hakala Troy , Mitchell Jessie 
Published: June 2024

AbstractBackgroundThe ability to self‐advocate or have a say in one's care is integral to personalised care after acquired brain injury (ABI). This study aimed to understand what constitutes self‐advocacy and associated barriers and facilitators throughout hospital transitions and into the community.MethodQualitative methodology was employed with semistructured interviews conducted with 12 people with ABI and 13 family members. Interviews were conducted at predischarge (in‐person or via telephone) and 4 months postdischarge (via telephone) from the brain injury rehabilitation unit of a tertiary hospital. Data were thematically analysed using a hybrid deductive–inductive approach.ResultsSelf‐advocacy reflects the process of reclaiming agency or people's efforts to exert influence over care decisions after ABI. Agency varies along a continuum, often beginning with impaired processing of the self or environment (loss of agency) before individuals start to understand and question their care (emerging agency) and ultimately plan and direct their ongoing and future care (striving for agency). This process may vary across individuals and contexts. Barriers to self‐advocacy for individuals with ABI include neurocognitive deficits that limit capacity and desire for control over decisions, unfamiliar and highly structured environments and lack of family support. Facilitators include neurocognitive recovery, growing desire to self‐advocate and scaffolded support from family and clinicians.ConclusionSelf‐advocacy after ABI entails a process of reclaiming agency whereby individuals seek to understand, question and direct their ongoing care. This is facilitated by neurocognitive recovery, growing capacity and desire and scaffolded supports. Research evaluating approaches for embedding self‐advocacy skills early in brain injury rehabilitation is recommended.Patient or Public ContributionTwo caregivers with lived experience of supporting a family member with ABI were involved in the design and conduct of this study and contributed to and provided feedback on the manuscript.
ALK‐rearranged, CD34‐positive spindle cell neoplasms resembling dermatofibrosarcoma protuberans: a study of seven cases
Authors: Agrawal Shruti , Ameline Baptiste , Folpe Andrew L , Azzato Elizabeth , Astbury Caroline , Mentzel Thomas , Knapp Calvin , Rütten Arno , Creytens David , Sukov William , Baumhoer Daniel , Billings Steven D , Fritchie Karen J 
Published: June 2024

AimsThe majority of dermatofibrosarcoma protuberans (DFSP) harbour PDGFB or PDGFD rearrangements. We encountered ALK expression/rearrangement in a PDGFB/D‐negative CD34‐positive spindle cell neoplasm with features similar to DFSP, prompting evaluation of ALK‐rearrangements in DFSP and plaque‐like CD34‐positive dermal fibroma (P‐LDF).Methods and ResultsWe searched the archives of academic institutions for cases previously coded as DFSP and P‐LDF. NGS‐naïve or PDGFB‐negative DFSP were screened for ALK (clone D5F3) expression by immunohistochemistry. NGS or ALK FISH was performed on ALK‐positive cases. Methylome profiling studies were performed and compared with conventional DFSP. One case of “DFSP” and two “P‐LDF” with ALK expression were identified from the archives, while four cases were detected prospectively. These seven cases (6F:1M; 8 months to 76 years) arose in the dermis of the arm (two), scalp, eyelid, thigh, abdomen, and shoulder and ranged from 0.4 to 4.2 cm. Tumours were composed of spindled cells and displayed a storiform growth pattern. Cytologic atypia was absent, and mitotic figures were scarce (0–2/10 HPFs, high power fields). The lesional cells were diffusely positive for CD34 and ALK and negative for S100 protein. By NGS (n = 5), ALK fusion partners included DCTN1 (2), PLEKHH2, and CLIP2 in DFSP‐like cases and FLNA in P‐LDF‐like lesions. ALK FISH was positive in one (of two) cases previously labelled P‐LDF. Methylome profiling of two (of three) ALK‐rearranged DFSP‐like tumours showed clustering with conventional DFSP in the UMAP dimension reduction plot. To date, no tumour has recurred (n = 2; 26, 27 months).ConclusionWe describe a cohort of novel ALK‐rearranged tumours with morphologic features similar to DFSP.