bluuebunny/crossref_metadata_2025_split huggingface dataset:
Processing of engineering and geological survey data for determining parameters of the hardening soil model on the example of clay soils in the Nizhny Novgorod region
Authors: Maleeva A. N. , Kharichkin A. I. 
Published: February 2025

Introduction. The paper examines the key aspects of obtaining parameters for the hardening soil model used in the analysis of soil bases. This model is increasingly popular due to its effectiveness in calculating various structures, such as pile foundations, retaining walls, and anchorages.Aim. To analyze the experience of obtaining parameters for the hardening soil model based on laboratory data derived from engineering and geological surveys.Materials and methods. The methodology involved analyzing and processing the results of laboratory studies on soils in the Nizhny Novgorod region. The laboratory tests were performed as part of engineering surveys. The parameters were optimized and the model was calibrated for the obtained parameters of the hardening soil model using the Plaxis software suite, specifically within the Soil Test module.Results. A set of design parameters was obtained for the hardening soil model. A comparison between laboratory results and numerical modeling outcomes was performed to confirm the accuracy and reliability of these parameters. This stage of the study demonstrated that the optimized and calibrated parameters of the hardening soil model provide a high degree of consistency between laboratory data and numerical calculations.Conclusions. Currently, no universally accepted methodology exists for processing the results of laboratory tests and statistical analysis. Overall, the analysis of results and parameter selection for implementing the calculation model remains at an expert level and is not regulated by normative documents. Further research in this area will enable the development of more effective methods and approaches, contributing to advancements in both science and practice in geotechnical engineering.
Strong Rest-UV Emission Lines in a “Little Red Dot” Active Galactic Nucleus at z = 7: Early Supermassive Black Hole Growth alongside Compact Massive Star Formation?
Authors: Akins Hollis B. , Casey Caitlin M. , Berg Danielle A. , Chisholm John , Cloonan Aidan P. , Franco Maximilien , Finkelstein Steven L. , Fujimoto Seiji , Koekemoer Anton M. , Kokorev Vasily , Lambrides Erini , Robertson Brant E. , Taylor Anthony J. , Coulter David A. , Fox Ori , Karmen Mitchell 
Published: February 2025

Abstract
JWST has now revealed a population of broad-line active galactic nuclei (AGN) at z ≳ 4 characterized by a distinctive spectral energy distribution shape, with a very red rest-frame optical and very blue rest-frame UV continuum. While the optical continuum is thought to originate from the accretion disk, the origin of the UV continuum has been largely unclear. We report the detection of the strong rest-frame UV emission lines of C iii] λλ1907, 1909 and C iv
λλ1549, 1551 in a “little red dot” AGN, COS-66964. Spectroscopically confirmed at z = 7.0371, COS-66964 exhibits broad Hα emission (FWHM ∼ 2000 km s−1) and weak broad Hβ, implying significant dust attenuation to the broad-line region (

A

V

=
3
.

9

−
0.9

+
1.7

). The Hα line width implies a central supermassive black hole (SMBH) mass of

M

BH

=

1
.

9

−
0.7

+
1.6

×
1

0

7

M
⊙ and an Eddington ratio λ ∼ 0.3–0.5. While marginal He ii
λ4687 and [Fe x] λ6376 detections further indicate that the AGN dominates in the rest-frame optical, the nondetection of He ii
λ1640 in the UV despite high EW C iii] and C iv (∼35 Å) is more consistent with photoionization by massive stars. The nondetection of Mg ii
λλ2800 is similarly inconsistent with an AGN scattered light interpretation. Assuming the rest-frame UV is dominated by stellar light, we derive a stellar mass of

log

M

⋆

/

M

⊙

∼
8.5

, implying an elevated M
BH/M
⋆ ratio ∼2 orders of magnitude above the local relation, but consistent with other high-z AGN discovered by JWST. The source is unresolved in all bands, implying a very compact size ≲200 pc in the UV. This suggests that the simultaneous buildup of compact stellar populations (i.e., galaxy bulges) and the central SMBH is ongoing even at z ≳ 7.
DNMT1 promotes the proliferation and migration of gastric cancer cells by inducing microRNA-125a-5p methylation to promote SERPINE1 protein
Authors: Xie Hui , Wang Hui , Li Ru-Hong , Zhang Yue-Wen , Fan Xi-Rui , He Xiao-Xue , Guan Ao-Ran 
Published: February 2025

BACKGROUND
Gastric cancer (GC) is a malignant tumor originating from gastric mucosal epithelial cells that has high morbidity and mortality. microRNAs (miR) are important diagnostic markers and therapeutic targets in this disease.
AIM
To explore the mechanism of miR-125a-5p in the pathogenesis of GC.
METHODS
The expression levels of miR-125a-5p, SERPINE1 and DNMT1 in GC cells and tissues were detected by real-time polymerase chain reaction (PCR) and Western blotting. Methylation-specific PCR was used to detect the level of miR-125a-5p methylation. A cell counting kit 8 assay, scratch test, and a Transwell assay were performed to detect the proliferation, migration, and invasiveness of HGC27 cells, respectively. The expression of the epithelial mesenchymal transition (EMT)-related proteins E-cadherin, N-cadherin and vimentin in HGC27 cells was detected by Western blotting, while the expression of vimentin was detected by immunofluorescence.
RESULTS
This study revealed that miR-125a-5p was expressed at low levels in GC clinical samples and cells and that miR-125a-5p overexpression inhibited the proliferation, migration, invasiveness and EMT of GC cells. Mechanistically, miR-125a-5p can reduce GC cell proliferation, promote E-cadherin expression, inhibit N-cadherin and vimentin expression, and reduce the EMT of GC cells, thus constraining GC cells to a certain extent. Moreover, DNMT1 inhibited miR-125a-5p expression by increasing the methylation of the miR-125a-5p promoter, thereby promoting the expression of SERPINE1 , which acts together with miR-125a-5p to exert antagonistic effects on GC.
CONCLUSION
Our study revealed that DNMT1 promoted SERPINE1 protein expression by inducing miR-125a-5p methylation, which led to the proliferation, migration and occurrence of EMT in GC cells.
SURVEILANS KUALITAS AIR MINUM RUMAH TANGGA DI WILAYAH KERJA PUSKESMAS JOMBANG, KOTA CILEGON TAHUN 2023
Authors: Hayat Fauzul , Kurniatillah Nia , Ferial Linardita 
Published: February 2025

Menjamin kualitas air minum aman sampai dengan tingkat Rumah Tangga diperlukan penguatan upaya pengawasan kualitas air melalui kegiatan surveilans. Tujuan dari penelitian ini adalah untuk mengetahui gambaran hasil kegiatan surveilans kualitas air minum rumah tangga di wilayah kerja puskesmas Jombang Kota Cilegon. Penelitian ini merupakan penelitian deskriptif dengan metode observasional. Pengumpulan data dilakukan pada bulan Januari-Maret 2025. Teknik pengambilan sampel penelitian adalah purposive sampling. Populasi dalam penelitian adalah seluruh sumber air minum rumah tangga. Besar sampel berdasarkan perhitungan Slovin sebanyak 36 sampel. Analisis dilakukan melalui olahan rangkuman dan kajian data yang tersedia di Puskesmas Jombang Kota Cilegon tahun 2023. Hasil penelitian menunjukkan bahwa dari 36 sampel air minum rumah tangga yang dilakukan pemeriksaan fisik yaitu kadar pH rata-rata sebesar (7,7), TDS ditemukan rata-rata sebesar (362,42 mg/L), dengan konsentrasi minimum (24 mg/L) dan maksimum (785 mg/L). Pemeriksaan mikrobiologi yaitu sebanyak 0 (0,0%) telah memenuhi syarat kesehatan. Pemeriksaan kimiawi diantaranya adalah kadar fluoride (F) rata-rata sebesar 1,305 mg/L, dengan konsentrasi minimum dan maksimum (0,783 mg/L dan 1,588 mg/L). Kadar mangan (Mn) rata-rata sebesar 0,034 mg/L, dengan konsentrasi minimum dan maksimum (0,021 mg/L dan 0,048 mg/L). Kadar Besi (Fe) ditemukan rata-rata sebesar 0,015 mg/L, dengan konsentrasi minimum (0,010 mg/L) dan maksimum (0,021 mg/L). Kandungan Timbal (Pb) ditemukan rata-rata sebesar 0,083 mg/L, dengan konsentrasi minimum (0 mg/L) dan maksimum (1 mg/L). Masih terdapat parameter fisik dan kimiawi yang tidak memenuhi syarat kesehatan diperluan upaya edukasi masyarakat, advokasi, dan upaya bersama pemerintah daerah setempat dalam pengelolaan sumber air minum rumah tangga sehingga aman untuk dikonsumsi.
A STUDY OF MEDICINE MANAGEMENT IN PUBLIC HEALTH CENTER
Authors: Sari Nur Mila , Napirah Muhammad Ryman , Windy Widy Try 
Published: February 2025

In Indonesia, drug expenditures that have been roughly fourty percent are seen as exorbitant. Drug availability is decreased, pharmaceuticals become scarce, a large number of drugs accumulate as a result of poor drug planning, and irrational drug use drives up drug costs. The aim to Find out about the Public Health Center's drug needs planning, distribution, storage, and recording and reporting is the goal. design of qualitative research using a case study methodology. In their working area, the Public Health Center and Integrated Service Center, this study was carried out in 2017. The Public Health Center's director served as the study's primary informant. The result is Public Health Center and the Health Office collaborate to plan for drug needs; nonetheless, some medications are required but not included in the e-catalog. The Public Health Center's drug storage is set up according to the FIFO and FEFO systems, but there are no dedicated cabinets for narcotics and psychiatric medications, and the air temperature does not yet meet regulations. Unavailable medications cause problems with patient medicine distribution, leading to ineffective and inefficient services. Due to a shortage of pharmaceutical health workers, drug recording and reporting are not completed on time. According to the study's findings, there are challenges with drug management at the Public Health Center, ranging from organizing drug requirements, storing, distributing, and recording and reposrting drugs.
Implementation of Early Detection Activities for Stunting in Toddlers in Posyandu CMB Kotawaringin Timur Regency
Authors: Oki Alestari Rena , Widia Lidia , Safitri Neneng 
Published: February 2025

Stunting is malnutrition that occurs when the baby is in the womb and at birth, but stunting only appears after the child is 2 years old. Stunting is caused by multi-dimensional factors. The most decisive intervention at 1,000 HPK (First 1000 Days of Life). (Ministry of Villages, Development of Disadvantaged Regions and Transmigration, 2017). The result is disruption of brain development, intelligence, physical growth disorders and metabolic disorders in the body (Ministry of Villages, Development of Disadvantaged Regions and Transmigration, 2017). The results of the 2013 Basic Health Research (Riskedas) showed that the prevalence of stunting reached 37.2%. The aim of this implementation is that mothers of toddlers have a better understanding of early detection of stunting in mothers of toddlers. The service method uses counseling using lectures, questions and answers, and examining the growth and development of toddlers using leaflets and giving awards to toddlers who have the best growth and development. Implementation activities will be carried out on June 19, 2024, at Posyandu CMB East Kotawaringin. The results of this community service activity can be said to be successful. This can be observed in the level of attendance and activeness of participants. This activity took place in an orderly and good manner without experiencing significant obstacles. The follow-up that needs to be taken is to continuously monitor the growth and development of toddlers at Posyandu as an early detection of stunting in toddlers.
O reconhecimento do migrante como sujeito de direitos no Brasil a partir dos desafios vivenciados na Amazônia brasileira
Authors: Baettker Ellene Carla , Oliveira Márcia Maria de , Roberti Junior João Paulo 
Published: February 2025

Este artigo examina o reconhecimento do migrante como sujeito de direitos no Brasil, com um enfoque específico na migração venezuelana no estado de Roraima. Baseado na metodologia qualitativa e no método da análise de conteúdo, o estudo levanta dados sobre a mobilidade humana na Amazônia a partir da legislação migratória e da perspectiva do migrante como detentor de direitos. O objetivo desta pesquisa é apresentar o migrante como um cidadão participante nos processos de inclusão social e acesso às políticas públicas, especialmente aquelas relacionadas à inclusão e renda. Ao explorar esses temas, o artigo busca destacar os desafios e as oportunidades emergentes para os migrantes no contexto brasileiro, particularmente em Roraima. Como resultado da análise, observa-se a emergência de novos processos e modalidades de inserção dos migrantes na sociedade, os quais desafiam as estruturas estabelecidas do estado de direito. Esta pesquisa contribui para uma compreensão mais abrangente das dinâmicas migratórias na região, bem como para o debate sobre políticas públicas e direitos humanos relacionados à migração. Conclui-se que há novos processos e modalidades de inserção dos migrantes na sociedade que desafiam o estado de direito.
Efeitos das reformas políticas educacionais no currículo de língua portuguesa: reflexão sobre a influência da colonialidade
Authors: Santos Poliana Boone dos , Brandão Helen Moura Pessoa 
Published: February 2025

A língua/linguagem pode ser considerada como um elemento essencial para a construção de identidades, sobretudo há a possibilidade de atuar como ferramenta de disseminação de ideologias por meio do processo formativo e questões culturais e políticas. Em razão disso, este artigo pretende refletir sobre os efeitos das políticas educacionais no ensino da Língua Portuguesa, analisando a possibilidade de influência da Colonialidade no currículo. Para tanto, apresentamos como aporte teórico Fanon (2008), Mignolo (2020), Maldonado-Torres (2016, 2018), Quijano (2005, 2006, 2009), dentre outros intercessores teóricos. Como metodologia, este estudo apresenta natureza qualitativa e baseia-se na Pesquisa de intervenção-cartográfica. Os dados produzidos evidenciam os efeitos da colonização portuguesa na educação, especialmente por meio do currículo eurocentrado o qual promove a colonialidade do saber, bem como restringe o fazer pedagógico e produz um esvaziamento do currículo.
Aquaponia: uma abordagem sustentável para a produção de alimentos
Authors: Oliveira Diana Carla Fernandes , Miranda Ana Luiza de Souza , Pereira Miriam de Andrade , Batista Giovanni Aleixo , Gomes Maria Emília de Sousa , Paulino Renan Rosa , Freitas Rilke Tadeu Fonseca de 
Published: February 2025

Aquaponia é um sistema integrado de produção de alimentos que combina aquicultura e hidroponia, permitindo o cultivo simultâneo de peixes e plantas em um ambiente recirculante. Nesse sistema, os resíduos provenientes da aquicultura, como fezes e excesso de ração, fornecem nutrientes essenciais para o crescimento das plantas que filtram e purificam a água, criando um ciclo fechado e sustentável. Os sistemas mais comuns em aquaponia incluem o leito de cultivo, o Deep Water Culture (DWC) e o Nutrient Film Technique (NFT), cada um com vantagens e limitações específicas. A escolha das espécies e do sistema hidropônico depende de fatores como a densidade dos peixes, a disponibilidade de nutrientes e as condições ambientais locais. As espécies mais comuns utilizadas no cultivo integrado são a tilápia, devido ao seu rápido crescimento e alta demanda comercial, e as plantas como alface e cebolinha, que requerem baixos a médios níveis de nutrientes. Apesar de seu grande potencial para a produção sustentável de alimentos, a aquaponia enfrenta desafios, como a gestão de resíduos, o controle de doenças e a adaptação a diferentes contextos regionais. Com o avanço da tecnologia e da pesquisa, a aquaponia tem o potencial de se tornar uma solução viável para a produção de alimentos em sistemas agrícolas sustentáveis.
Pichia kudriavzevii em onicomicose: um relato de caso
Authors: Vignoto Maria Fernanda Miriani , Valverde Tamires Leite , Júnior Oscar de Oliveira Santos , Ribeiro Ana Claudia Ferreira , Polo Ana Caroline , Bortoloto Carolina , Machado Deborah Heloise Fernandes , Ecker Alessanda Barrochelli da Silva 
Published: February 2025

As infecções fúngicas ungueais, conhecida como onicomicose representam 20% a 50% das onicopatias em todo o mundo. São infecções comuns, de difícil tratamento e com frequentes insucessos terapêuticos. O objetivo deste estudo foi identificar o agente causador de uma onicomicose através de métodos laboratoriais e tratar adequadamente, visando à melhora clínica do paciente. O paciente do sexo masculino, de 54 anos, trabalhador rural e de lavanderia, portador do vírus da hepatite B, relata o aparecimento de lesões ungueais há aproximadamente 10 anos, com aspecto distrófico, fissuras, e após o manuseio de água e produtos químicos a unha apresentava aspecto inflamatório com agravamento da lesão, resultando em dor. Além disso, foi administrado durante anos medicamentos testados empiricamente, sem a identificação do agente causador, levando a breve melhora das lesões, mas com recidivas posteriores, contaminando assim outras unhas saudáveis e desencorajando o paciente a persistir no tratamento. A partir de exames laboratoriais, como micológico direto, cultura, microcultivo, foi possível identificar Pichia kudriavzevii como patógeno causador da onicomicose. O sistema terapêutico foi realizado com itraconazol oral 200 mg/dia por 12 semanas, associado ao creme tópico de tetraciclina 25 mg/g e anfotericina B 12,5 mg/g à noite, e spray de clotrimazol 10 mg/ml pela manhã. Para minimizar os riscos hepáticos, as enzimas AST, ALT e GGT foram monitoradas mensalmente. O tratamento resultou em melhora clínica significativa, ressaltando a importância da identificação laboratorial correta para a escolha do tratamento antifúngico adequado, evitando recidivas e promovendo a eficácia terapêutica.
Análise dos institutos do fresh start e do discharge à luz do Bankruptcy Code de 1978 e algumas implicações no Brasil
Authors: Miranda Breno Augusto Pinto de 
Published: February 2025

Este artigo examina o instituto do "fresh start" do Bankruptcy Code de 1978 nos Estados Unidos e suas implicações no ordenamento jurídico brasileiro, com foco na comparação entre os regimes de insolvência dos dois países. A análise parte da premissa de que o sistema norte-americano prioriza a reintegração do devedor, seja pessoa física ou jurídica, à atividade econômica, enquanto o modelo brasileiro, ainda que evoluído pela Lei 14.112/2020, permanece condicionado a entraves legislativos e culturais. O estudo discorre sobre os fundamentos constitucionais que amparam a preservação da atividade empresarial e a dignidade do devedor, demonstrando como o "fresh start" se alicerça na exoneração de dívidas para fomentar o reingresso ao mercado. Destaca-se a relevância de instrumentos como o discharge e as reformas legislativas no Brasil para alinhar o direito concursal aos princípios de inclusão econômica e social. O trabalho conclui pela necessidade de uma modernização legislativa no Brasil, inspirada no paradigma norte-americano, para equilibrar a proteção aos credores e a recuperação dos devedores, promovendo um sistema jurídico mais eficiente e humanizado.
Credibility of Testimony in the Psychological Expertise of Victims of Violence: A Systematic Review
Authors: Gonzales-Quispe Raúl , Robles Elizabeth Dany Araujo , Elena Cuenca Robles Nancy , Vila Roxana Maribel Cárdenas , Tarazona María Rosario Palomino , Luy-Montejo Carlos Augusto 
Published: February 2025

Purpose: Psychological expertise is a technical and methodological procedure, recognized for its relevance and usefulness.

Theoretical Framework: The theoretical basis that we propose is based on Undeutsch’s hypothesis, which states that the events that happen differ in content, quality and expression from those that are imaginary. In the justice system, they determine the psychological affectation, of events occurred within.

Method: The privacy and to provide methodological rigor, must be subjected to the credibility of the testimony, in this sense, the aim is to determine the importance of the credibility of the testimony in the psychological expertise, in victims of violence, for which it has been taken into consideration, documents in English and Spanish of the search engines Scopus.

Result: Redalyc, Researchgate, Semantic Scholar, finding 361 documents of which 7 experimental research studies were selected, whose research instrument was the semi-structured cognitive interview, subjected to criteria-based content analysis (CBCA), and external verification, highlighting that these documents agree that the credibility of testimony is fundamental to sustain psychological expertise in a judicial process.

Conclusion: For the present work, we have focused on experimental research, whose conclusions allow us to reaffirm that the interviews that give rise to psychological reports, in cases of violence that occurred in the private sphere, can be subjected to the credibility of testimony based on criteria and external corroboration, as they are unique evidence before the justice system.
Strategies for Committing Narcotics Abuse by Children Through Community Policing
Authors: Zulkarnain  , Rosidah Nikmah , Siswanto Heni 
Published: February 2025

Objective: Law enforcement is the responsibility of the police and the community. Therefore community policing has a strategic role in overcoming narcotics abuse by children. This article examines and analyzes community policing strategies in efforts to deal with children as drug abusers.

Method: The research uses normative and empirical juridical methods with statutory and case approaches. Data collection was carried out through observation, interviews, and document studies. Furthermore, the data obtained were analyzed descriptively and qualitatively.

Result: Community policing as a strategy for overcoming narcotics abuse by children includes changing the legal culture by prioritizing non-penal efforts by involving all components of society; optimizing community policing programs in increasing public legal awareness, community policing activities based on charitable or non-commercial, strengthening the authority of Bhabinkamtibmas as the bearer of community policing; the implementation of the main functions and duties of Bhabinkamtibmas as the bearer of community policing is directed at development, monitoring, supervision, prosecution, and law enforcement activities that are pre-emptive, preventive and repressive in ways persuasive and humane.

Conclusion: Community policing in efforts to combat narcotics by children focuses on non-penal efforts. This is implemented by policing the community from downstream to upstream and from the bottom up with the involvement of all components of society and local government as well as electronic media to prevent Narcotics theft by children.
Mundskylle­væskers rolle i hjemme­tandplejen
Authors: Ademovski Seida Erovic , Laine Merja Anneli , Koldsland Odd Carsten , Ekstrand Kim 
Published: February 2025

Klinisk relevans
Der findes to typer af mundskyllevæsker: kosmetiske mundskyllevæsker, som ikke har nogen kemisk/biologisk effekt, og terapeutiske mundskyllevæsker, som har aktive ingredienser. Fluoridholdige mundskyllevæsker (FMV) er et eksempel på terapeutiske mundskyllevæsker og har betydelig cariesreducerende virkning, hvis de anvendes regelmæssigt i kombination med fluoridholdig tandpasta. FMV er et tiltag, der bør overvejes for patienter over femårsalderen med høj cariesrisiko. Klorhexidin mundskyl anbefales kun til kortvarig anvendelse og bør kun anskaffes efter samråd med tandlæge eller tandplejer. Der findes mundskyllevæsker med diverse aktive ingredienser, som angives at virke mod dårlig ånde, men ifølge systematiske oversigter er der begrænset evidens for effekt på intraoral halitose.