bluuebunny/crossref_metadata_2025_split huggingface dataset:
Xenoestrogen concentration in women with endometriosis or leiomyomas: A case-control study
Authors: Valdes-Devesa Victoria , Sanz-Rosa David , Thuissard-Vasallo Israel J. , Andreu-Vázquez Cristina , Sainz de la Cuesta Ricardo 
Published: June 2024

Background
Xenoestrogens are synthetic or naturally occurring chemicals capable of altering the endocrine system of humans and animals owing to their molecular similarity to endogenous hormones. There is limited data regarding their effects on women´s health. Chronic exposure to xenoestrogens can promote the development of estrogen-related diseases.

Objectives
To examine xenoestrogen concentration (TEXB-α) differences between women with leiomyomas or endometriosis and control women, and to study the relationship between the clinical and sociodemographic characteristics of these patients and their xenoestrogen levels.

Methods
Prospective case-control study. We selected 221 women who underwent surgery at Quironsalud Madrid University Hospital between 2017 and 2021. The cases included 117 patients: 74 women who underwent surgery for uterine leiomyomas, 21 with endometriosis, and 22 with both pathologies. The control group comprised 104 healthy women who underwent surgical procedures for other reasons. TEXB-α was determined in the omental fat of all patients. Using a questionnaire and reviewing the patients’ medical records, we collected sociodemographic data and other relevant variables.

Results
A significant majority of study participants (68.8%) had detectable levels of xenoestrogens. We found no association between TEXB-α levels in omental fat and the presence of myomas or endometriosis. In the case group, women living or working in Madrid Community exhibited, on average, 3.12 Eeq pM/g higher levels of TEXB-α compared to those working in other areas (p = 0.030). Women who referred to the use of estrogen-containing hormonal contraceptives had, on average, 3.02 Eeq pM/g higher levels of TEXB-α than those who had never used them (p = 0.022).

Conclusions
This study found no association between omental xenoestrogen levels and leiomyomas or endometriosis. However, their presence in most participants and their association with highly polluted areas emphasizes the importance of limiting environmental exposure to these substances. We also identified an association between hormonal contraceptive use and xenoestrogen concentration.
Difficulties of differential diagnosis of diabetic neurosteoarthropathy with purulent arthritis in patients with a short experience of type 1 diabetes mellitus
Authors: Savitskaya D. U. , Tokmakova A. Yu. , Doronina L. P. , Mitish V. A. , Bardiugov P. S. , Galstyan G. R. 
Published: June 2024

This paper examines the case of differential diagnosis of diabetic neuroosteoarthropathy (DNOA) and purulent arthritis (PA) in young patients with unsatisfactory control of type 1 diabetes mellitus (T1DM) and a short (8 years) duration of the underlying disease. Errors in the diagnosis of foot and ankle lesions made at the first stage of care create a clinical situation associated with a minimal risk of limb loss. At the second stage, during hospitalization in a specialized institution, a range of diagnostic and therapeutic measures was selected, which allowed for adequate diagnosis and differential diagnosis of the lesion, as well as its complex treatment, which made it possible to save the foot and ankle joint. This harmful event is due to the need for comprehensive multidisciplinary care in the selection of diagnostic testing and subsequent treatment of short-term patients with poorly controlled type 1 diabetes mellitus.
Numerical simulation for the slip impacts on the radiative nanofluid flow over a stretched surface with nonuniform heat generation and viscous dissipation
Authors: Alkaoud Ahmed , Khader Mohamed M. , Eid Ali , Megahed Ahmed M. 
Published: June 2024

Abstract
The growing fascination with nanofluid flow is motivated by its potential applications in a variety of industries. Therefore, the objective of this research article is to conduct a numerical simulation of the Darcy porous medium flow of Newtonian nanofluids over a vertically permeable stretched surface, considering magnetohydrodynamic mixed convection. Various attributes, such as the impacts of slip, thermal radiation, viscous dissipation, and nonuniform heat sources, are integrated to explore the behavior of the flow. The utilization of the boundary layer theory helps to describe the physical problem as a system of partial differential equations (PDEs). These derived PDEs are then converted to a system of ordinary differential equations (ODEs) through the application of suitable conversions. The outcomes are obtained using the finite difference method, and the effects of parameters on nanofluid flow are compared and visualized through both tabular and graphical representations. The outcomes have been computed and subjected to a comparative analysis with previously published research, revealing a remarkable degree of agreement and consistency. Consequently, these innovative discoveries in heat transfer could prove beneficial in addressing energy storage challenges within the contemporary technological landscape. The noteworthy main findings indicate that when the porous parameter, magnetic number, velocity slip parameter, viscosity parameter, and Brownian motion parameter are assigned higher values, there is an observable expansion in the temperature field. Due to these discoveries, we can enhance the management of temperature in diverse settings by effectively modulating the heat flow.
The impact of external financing during wartime on the economy of a country in war
Authors: Davydiuk Tetiana , Shymanska Kateryna 
Published: June 2024

This study delves into the effects of external financial support (official development assistance and foreign direct investments) on economic activity and welfare based on data from five nations injured by similar military conflicts from 2006 to 2021. Focusing on Ukraine, the research recommends ways for policymakers to navigate external financing during wartime. The employment rate, GDP per capita, inflation rate, and exports are the foundations for our analysis. The methodological approach employed regression analysis to measure the economic effect of external financing in wartime in these conflict-ridden nations. The findings reveal that increased foreign direct investment during wartime correlates with reduced employment rates, heightened GDP per capita, and increased exports. In addition, the negative impact of official development assistance ODA on employment was found, and it had a positive effect on exports but no significant effects on GDP per capita. A statistically significant impact on the inflation rate was not seen.
Influence of preharvest fungicides on decay incidence and fruit quality of mango fruits during storage
Authors: Darshan D. , Gill K.B.S. , Gill P.P.S. , Singh H. 
Published: June 2024

AbstractMango fruits' quality, marketability, and shelf life are significantly influenced by postharvest decay. Mango fruit disease development during storage is inhibited by fungicides. The objective of this investigation was to assess the relative effectiveness of two fungicides, azoxystrobin 18.2% + difenoconazole 11.4% SC and hexaconazole 5% SC, in mitigating postharvest deterioration of mango cv. ‘Langra’ during low temperature storage. Three pathogens were found associated with postharvest decay of mango, i.e. Colletotrichum gloeosporioides, Alternaria alternata, and Penicillium expansum. In comparison to untreated ones, the preharvest application of fungicide treatments provided noticeably better disease control. The foliar application of azoxystrobin 18.2% + difenoconazole 11.4% SC (0.1%) 15 days before the harvesting of fruits significantly improved fruit firmness, soluble solid content, titratable acidity, reduced the disease incidence, percentage disease index, and lesion diameter followed by the application of hexaconazole 5% SC (0.1%) compared to the control. Furthermore, it was found that pre-harvest fungicide spraying of azoxystrobin 18.2% + difenoconazole 11.4% SC (0.1%) was an effective treatment for lowering postharvest deterioration and enhancing the physio-chemical characteristics of mango fruits during low-temperature storage.
ИССЛЕДОВАНИЕ ТРАНСФОРМАЦИЙ ТРУДОВЫХ РЫНКОВ ПРИ ВНЕДРЕНИИ ИННОВАЦИОННЫХ ТЕХНОЛОГИЙ ИСКУССТВЕННОГО ИНТЕЛЛЕКТА
Authors: Погорелова Людмила Александровна 
Published: June 2024

Целью исследования является анализ изменений на рынке труда в процессе интеграции технологий искусственного интеллекта в различные сферы народного хозяйства.
Методологическую базу исследования представляет системный анализ опыта отечественных и зарубежных ученых в области оценки перспектив воздействия искусственного интеллекта на человеческий капитал.
Результаты исследования: проведен анализ последствий воздействия систем искусственного интеллекта на человеческий капитал, обозначены основные проблемы профессионального и социального характера.
Перспективы исследования заключаются в необходимости осознания обществом проблем и выработки оптимальных перспектив развития, связанных с негативным воздействием технологий искусственного интеллекта на человеческий капитал.
ИНДУСТРИЯ 4.0: СОЦИОКУЛЬТУРНЫЕ ПРЕОБРАЗОВАНИЯ И ПУТИ АДАПТАЦИИ В СОВРЕМЕННОМ ОБЩЕСТВЕ
Authors: Кузьмичева Людмила Николаевна , Хурина Ксения Руслановна 
Published: June 2024

Целью исследования является анализ социокультурных аспектов Четвертой промышленной революции с учетом высказанных Швабом тезисов о ее влиянии на экономическую, политическую и социальную жизнь общества. Исследование направлено на выявление ключевых факторов развития этой революции, анализ ее позитивных и негативных аспектов, а также оценку ее воздействия на различные сферы жизни современного общества. Дополнительно исследование ставит целью проанализировать перспективы адаптации государственных структур к вызванным этой революцией изменениям в управлении и оценить роль цифровых технологий в повышении прозрачности, ответственности и участия граждан в политических, экономических и культурных процессах.
Методологическую базу исследования составляет концептуальный анализ, аналитический подход, анализ литературы и научных источников, связанных с различными аспектами.
Результаты исследования включают выявление признаков Четвертой промышленной революции, обоснование ее неизбежности, идентификацию основных вызовов и проблем человечества с ней связанных, возможные методы и принципы их преодоления. Обозначены сферы жизни, которые могут быть при этом затронуты, определены возможные позитивные и негативные последствия цифровизации, автоматизации, развития нано- и биотехнологий.
Перспективы исследования. Исследование даст возможность сформировать новое видение анализа этических вопросов, связанных с использованием новых технологий, и исследование угроз в области кибербезопасности, которые возникают в результате распространения цифровых технологий
Thyroid status in patients with early stages of cancer of various localization
Authors: Bandovkina V. A. , Frantsiyants E. M. , Salatova A. M. , Еngibaryan M. A. , Volkova V. L. , Cheryarina N. D. 
Published: June 2024

Purpose of the study. To determine the thyroid status of primary cancer patients in the early stages of uterine body cancer, kidney cancer, breast cancer, skin melanoma and lung cancer without a history of endocrine pathology.Patients and methods. The content levels of thyroid-stimulating hormone (TSH), thyroid hormones (THs) T4 and T3 of total and free forms were determined in the blood serum by RIA method in 132 patients with breast cancer, uterine body cancer, lung cancer, kidney cancer and skin melanoma (average age 55 years). The comparison group consisted of practically healthy donors.Results. Only in skin melanoma, serum TSH levels were reduced by 1.5 times (p < 0.05). The T4 content was reduced by 1.4–1.7 times (p < 0.05) in uterine body cancer and kidney cancer, increased in lung cancer patients and 16 % of breast cancer patients by 1.4–1.7 times though (p < 0.05). A 1.3–1.5‑fold low (p < 0.05) T3 level was found in breast cancer, kidney cancer, and skin melanoma, while an 1.6‑fold increase (p < 0.05) was found in uterine body cancer. The revealed changes in THs by the type of clinical hyperthyroidism are an increase of 1.8 times (p < 0.05) FT3 on the background of low TSH in the blood in patients with skin melanoma, and by the type of hyperthyroxinemia in patients with lung cancer and breast cancer, consisting in increased concentrations of T4 and FT3, and with free and total T3 levels in patients uterine body cancer, as well as FT4, without changes in TSH in the blood serum of patients, may be associated with the features of malignant pathology, since it is known that THs are proliferation stimulants and can build up in tumors.Conclusion. The development of a malignant tumor even in the early stages of the disease is perceived by the body as a threat for homeostasis and the response to the occurrence of neoplasm is the reaction of the hypothalamicpituitary-thyroid regulatory axis. As an outcome, patients develop euthyroid disorder syndrome.
The Performance of Drought Indices on Maize Production in Northern Nigeria Using Artificial Neural Network Model
Authors: Adepoju Adedayo A. , Ogundunmade Tayo P. , Adenuga Grace O 
Published: June 2024

Drought is widely known to put the ecosystem at risk. It ensues when there is a major rainfall shortage that causes hydrological discrepancies and alters the land productive structures. The degree of rainfall influences the growth and harvests of maize, particularly where irrigation is not practicable. In some parts of northern Nigeria, rainfall is unpredictable and often lower than the quantity needed for a viable crop. For the detection, classification, and control of drought conditions, drought indices are used. There has been notable progress in the last few years in terms of modelling droughts by utilizing statistical or physical models. Despite the successes documented by most of these approaches; a plain, effective, and well-built statistical model is the artificial neural network (ANN). The use of artificial neural networks (ANN) to evaluate the impact of drought indices on maize output in the 17 northern Nigerian states is presented in this research. For a 25-year period from 1993 to 2018, observed annual data of drought indices, RDI, and the Palmer drought indices, which comprise SCPDSI, SCPHDI, and SCWLPM, as well as maize yield (measured in tonnes) in Northern states of Nigeria. The ANN model was evaluated using several activation functions (sigmoid, hyperbolic tangent, and rectified linear unit), hidden layers (1, 2, and 3), and training sets (70%, 80%, and 90%). The Mean Square Error (MSE) was employed to evaluate each ANN model's performance. In summary, most of the states' lowest mean square errors (MSEs) were generated via RELU. Also, as the training percentage increases, the mean square error increases.
DESKRIPSI BERPIKIR MATEMATIS SISWA PADA PENYELESAIAN MASALAH AKM NUMERASI DITINJAU BERDASARKAN LEVEL KECERDASAN EMOSIONAL [DESCRIPTION OF STUDENTS' MATHEMATICAL THINKING IN SOLVING AKM NUMERACY PROBLEMS BASED ON EMOTIONAL INTELLIGENCE LEVELS]
Authors: Nuratiqoh Nuratiqoh , Hidayanto Erry , Chandra Tjang Daniel 
Published: June 2024

<p>The purpose of this study is to describe how students' mathematical thinking processes unfold when addressing AKM Numeracy problems based on Mason's theory, taking into account emotional intelligence. This research is descriptive in nature with a qualitative approach. The research subjects consist of students categorized into high, moderate, and low levels of emotional intelligence. Research instruments include emotional intelligence questionnaires, AKM numeracy problem sheets, and interview guides. The research findings indicate that students with high levels of emotional intelligence are capable of fulfilling the three stages of mathematical thinking processes in problem-solving, namely entry, attack, and review. However, they have not fully met the extend aspect in the review stage. Students with moderate emotional intelligence can fulfill all aspects in the entry and attack stages but have not met the check and extend aspects in the review stage. Meanwhile, students with low emotional intelligence can only fulfill the know aspect in the entry stage, the try aspect in the attack stage, and the reflect aspect in the review stage.</p><p><strong>BAHASA INDONESIA ABSTRACT: </strong>Penelitian ini mempunyai tujuan untuk menggambarkan bagaimana proses berpikir matematis siswa ketika mengatasi masalah AKM Numerasi berdasarkan teori Mason ditinjau dari kecerdasan emosional. Jenis penelitian ini bersifat deskriptif dengan pendekatan kualitatif. Subjek penelitian yang dipilih yaitu siswa yang memiliki level kecerdasan emosional tinggi, sedang, dan rendah. Instrumen penelitian mencakup lembar angket kecerdasan emosional, lembar soal AKM numerasi, dan panduan wawancara. Berdasarkan hasil penelitian, ditemukan bahwa siswa dengan tingkat kecerdasan emosional tinggi mampu memenuhi tiga tahap proses berpikir matematis dalam memecahkan masalah, yaitu tahap <em>entry</em>, <em>attack</em>, dan <em>review</em>. Meskipun demikian, siswa dengan kecerdasan emosional tinggi belum sepenuhnya memenuhi aspek <em>extend</em> pada tahap <em>review</em>. Siswa dengan kecerdasan emosional sedang dapat memenuhi semua aspek pada tahap e<em>ntry </em>dan <em>attack </em>tetapi tidak dapat memenuhi aspek <em>check </em>dan <em>extend </em>pada tahap <em>review</em>. Siswa dengan kecerdasan emosional rendah hanya dapat memenuhi aspek <em>know </em>pada tahap <em>entry</em>, aspek <em>try </em>pada tahap <em>attack, </em>dan aspek <em>reflect </em>pada tahap <em>review.</em></p>
Osteopathic Students Have Decreased Match Rates in Orthopaedic Surgery Compared with Allopathic Students
Authors: Modica Anthony , Ranson Rachel , Williamson Tyler , Ponce Brent A. , Cohn Randy M. , Bitterman Adam D. 
Published: June 2024

Introduction:
Orthopaedic surgery continues to be one of the most competitive specialties to match into as a medical student, particularly for osteopathic medical students. Therefore, in this study, we sought to examine the prevalence of osteopathic students (DO) matching into orthopaedic surgery at traditional Accreditation Council for Graduate Medical Education (ACGME) accredited programs (former allopathic residency programs) in recent years.

Methods:
A retrospective review of National Residency Match Program annual reports and Association of American Medical Colleges's Electronic Residency Application Service Statistic reports were performed to determine the number of applications and match rates among osteopathic (DO) and allopathic (MD) medical students into orthopaedic surgery from 2019 to 2023. Data on the degree type of current residents at all ACGME-accredited residency programs were identified.

Results:
During the analyzed study period of 2019 to 2023, there were 3,473 (74.5%) allopathic students and 571 (59.9%) osteopathic students who successfully matched into orthopaedic surgery. This match rate for allopathic students was 74.5% compared with 59.9% for osteopathic students. Of the 3,506 medical students who hold postgraduate orthopaedic surgery positions at former allopathic programs over the past 5 years, only 58 (1.7%) hold an osteopathic degree. Of the 560 medical students who hold postgraduate orthopaedic surgery positions at former osteopathic programs over the past 5 years, 47 (8.4%) hold an allopathic degree. The match rate of allopathic students at former osteopathic programs is significantly higher than the match rate of osteopathic students at former allopathic programs.

Conclusions:
Osteopathic students continue to match into orthopaedic surgery at lower rates than their allopathic counterparts. In addition, there remains a consistent and low number of osteopathic students matching into former allopathic programs. Allopathic students also have a higher likelihood of matching into former osteopathic programs when compared with osteopathic students matching into previous allopathic orthopaedic surgery programs.
Social Media Promotions and Reviews Drive Online Shopping in Indonesia
Authors: Sari Elda Premesta , Indayani Lilik , Abadiyah Rifdah 
Published: June 2024

This study investigates the effects of social media promotions, prices, and product reviews on purchasing decisions for online shopping through Shopee in Sidoarjo. Using a quantitative approach, data from 96 respondents was collected via a Google Forms questionnaire. Analysis through SPSS version 26 revealed that social media promotions and product reviews significantly influence purchasing decisions, while price does not. These findings suggest that Shopee should focus on enhancing social media promotions and product reviews to boost consumer interest. Future research should explore additional factors to provide a more comprehensive understanding of online purchasing decisions.
Highlight:

Social media promotions significantly influence purchasing decisions on Shopee.
Product reviews have a notable impact on consumer buying choices.
Price does not significantly affect purchasing decisions for Shopee users.

Keywoard: Social media promotions, Product reviews, Online shopping, Purchasing decisions, Shopee
Topical Ophthalmic Anesthetics for Corneal Abrasions: Findings from a Cochrane Systematic Review and Meta-Analysis
Authors: Kuo Irene , Leslie Louis , Liu Su-Hsun 
Published: June 2024

Abstract

Background Despite potential benefit, outpatient use of topical ophthalmic anesthetics can result in poor healing, infection, scar, and blindness. An unbiased analysis of randomized controlled trials (RCTs) is needed to examine their effectiveness and safety compared with placebo or other treatments for corneal abrasions.Methods Cochrane Central Register of Controlled Trials, MEDLINE, Embase.com, Latin American and Caribbean Health Sciences, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform were searched on February 10, 2023, without restriction on language or publication date.Results Systematic review and meta-analysis of nine RCTs describing 314 participants with post-traumatic abrasions and 242 participants with post-surgical abrasions, with a median study length of 7 days (interquartile range, 7–14), show no evidence of a difference in pain control between anesthetics and placebo at 24 hours in post-trauma cases. Self-reported pain at 24 hours is reduced with anesthetics plus topical nonsteroid anti-inflammatory drug in post-surgical participants (mean difference [MD], -5.72 on a 10-point scale; 95% CI, -7.35 to -4.09; 1 RCT; 30 participants) and at 48 hours with anesthetics alone in post-trauma participants (MD, -5.68; 95% CI, -6.38 to -4.98; 1 RCT; 111 participants). Anesthetics are associated with 37% increased risk of non-healing defects (risk ratio, 1.37; 95% CI, 0.78 to 2.42; 3 RCTs; 221 post-trauma participants). All evidence is of very low certainty. Over 50% of trials have an overall high risk of bias.Conclusions Available evidence is insufficient to support outpatient use of topical anesthetics for corneal abrasions with respect to pain, re-epithelialization, and complication risk.