bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Activity of 2‐(Sulfonamido)methyl‐carbapenems: Discovery of a Novel, anti‐MRSA 1,8‐Naphthosultam Pharmacophore.
Authors: Wilkening R. R. , et al. et al. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Olivomycin A.
Authors: Roush William R. , Hartz Richard A. , Gustin Darin J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mirror Image Synthesis of Left Ends of Ciguatoxin and Gambiertoxin 4b.
Authors: Hosokawa Seijiro , Isobe Minoru 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cephalostatin Synthesis. Part 13. Synthesis of the North 1 Unit of the Cephalostatin Family from Hecogenin Acetate.
Authors: Kim Seongkon , Sutton Scott C. , Guo Chuangxing , LaCour Thomas G. , Fuchs P. L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cephalostatin Synthesis. Part 15. Synthesis of the South Unit of Cephalostatin. Part 7. Total Syntheses of (+)‐Cephalostatin 7, (+)‐Cephalostatin 12, and (+)‐Ritterazine K.
Authors: Jeong Jae Uk , Guo Chuangxing , Fuchs P. L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: [meso‐1,2‐Bis(2,6‐dichloro‐4‐hydroxyphenyl)ethylenediamine] dichloroplatinum(II), a Compound with a Specific Activity on Hormone‐Sensitive Breast Cancers — Evidence for a Diethylstilbestrol‐Like Mode of Action.
Authors: Schlemmer Richard , Spruss Thilo , Bernhardt Guenther , Schoenenberger Helmut 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Template Synthesis of Bismuth Telluride Nanowires.
Authors: Sapp Shawn A. , Lakshmi Brinda B. , Martin Charles R. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Clays and Catalysis: A Promising Future
Authors: Vaccari A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthetic Utility of the Hypercoordination of Boron and Aluminum
Authors: Maruoka Keiji , Ooi Takashi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Carotenoids
Authors: Pfander Hanspeter , Lanz Marc , Traber Bruno 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Some Applications of Microwave Irradiation in Cycloadditions
Authors: Carrillo J. R. , De La Cruz P. , Diaz‐Ortiz A. , Gomez‐Escalonilla M. J. , De La Hoz A. , Langa F. , Moreno A. , Prieto P. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Application of Nitrogen Ylide Cyclizations for Organic Synthesis
Authors: Beall L. Scott , Padwa Albert 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Iminium Cation Chemistry to Activated Indoles
Authors: Black David StClair 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in the Synthesis of Carbazoles and Anellated Indoles with Antitumor Activity: DNA‐Binding Ligands and Protein Kinase C Inhibitors
Authors: Pindur Ulf , Lemster Thomas 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Natural Products by Oxidative Phenolic Coupling — Phytochemistry, Biosynthesis, and Synthesis
Authors: Keseru G. M. , Nogradi M. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sulfimides (Sulfilimines). Applications in Stereoselective Synthesis
Authors: Taylor Paul C. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of 2‐Acylcycloalkane‐1,3‐diones
Authors: Rubinov Dmitry B. , Rubinova Irene L. , Akhrem Aphanasy A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lipases and Oxynitrilases as Tools for the Preparation of Highly Enantiopure Building Blocks for Synthetic Chemistry
Authors: Kanerva Liisa T. , Vanttinen Eero , Kiljunen Eero 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rearrangements and Cyclizations in Vinyl Radicals Promoted by Sulfanyl Radical Addition to Alkynes
Authors: Montevecchi Pier Carlo , Navacchia Maria Luisa 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Towards a Unitary Description of the Photochemical Isomerization Reactions in Pentaatomic Aromatic Heterocycles: The Case of Furan, Thiophene, Pyrrole, Isoxazole, Imidazole, and Pyrazole Derivatives
Authors: D'Auria Maurizio 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diels—Alder Reactions of Benzo[b]furan‐4,5‐diones and Benzo[b]furan‐4,7‐diones
Authors: Nebois Pascal , Fillion Houda 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dipolar Cycloadditions of Five and Six Membered Cyclic Nitrones to α,β‐Unsaturated Acid Derivatives
Authors: de March Pedro , Figueredo Marta , Font Josep 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular‐Sieve Catalysts for the Selective Oxidation of Linear Alkanes by Molecular Oxygen
Authors: Thomas John Meurig , Raja Robert , Sankar Gopinathan , Bell Robert G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Catalysis with Chiral Lanthanoid Complexes
Authors: Shibasaki Masakatsu , Sasai Hiroaki 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interleukin‐8: An Autocrine Inflammatory Mediator
Authors: Atta‐ur‐Rahman Atta‐ur‐Rahman , Harvey Kevin , Siddiqui Rafat A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recyclization of Carbo‐ and Heterocyclic Compounds Involving Malononitrile and Its Derivatives
Authors: Litvinov V. P. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Chemistry of Star‐Forming Regions
Authors: Williams David A. , Hartquist Thomas W. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Methods of Structure Determination of Prenylated Phenols with 1H and 13C NMR Spectra
Authors: Nomura Taro , Fukai Toshio 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Characterization of New meso‐Flavonylporphyrins by Fast Atom Bombardment Mass Spectrometry
Authors: Domingues Rosario M. , Santana‐Marques M. Graga O. , Neves M. G. P. M. S. , Silva A. , Cavaleiro J. A. S. , Ferrer‐Correia A. J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Monitoring the Progression of Organic Reactions on Solid Supports
Authors: Yan Bing 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors
Authors: Thaler Florian , Varasi Mario , Colombo Andrea , Boggio Roberto , Munari Davide , Regalia Nickolas , Rozio Marco G. , Reali Veronica , Resconi Anna E. , Mai Antonello , Gagliardi Stefania , Dondio Giulio , Minucci Saverio , Mercurio Ciro 
Published: June 2010

AbstractA series of amidopropenyl hydroxamic acid derivatives were prepared as novel inhibitors of human histone deacetylases (HDACs). Several compounds showed potency at <100 nM in the HDAC inhibition assays, sub‐micromolar IC50 values in tests against three tumor cell lines, and remarkable stability in human and mouse microsomes was observed. Three representative compounds were selected for further characterization and submitted to a selectivity profile against a series of class I and class II HDACs as well as to preliminary in vivo pharmacokinetic (PK) experiments. Despite their high microsomal stability, the compounds showed medium‐to‐high clearance rates in in vivo PK studies as well as in rat and human hepatocytes, indicating that a major metabolic pathway is catalyzed by non‐microsomal enzymes.
Oxaliplatin‐based chemotherapy (dexamethasone, high‐dose cytarabine, and oxaliplatin) ± rituximab is an effective salvage regimen in patients with relapsed or refractory lymphoma
Authors: Rigacci Luigi , Fabbri Alberto , Puccini Benedetta , Chitarrelli Ida , Chiappella Annalisa , Vitolo Umberto , Levis Alessandro , Lauria Francesco , Bosi Alberto 
Published: June 2010

AbstractBACKGROUND:Patients affected by relapsed or primary refractory lymphomas currently have a poor prognosis and no standard salvage treatment options. This study was carried out to assess the efficacy and safety of a dexamethasone, high‐dose cytarabine, and oxaliplatin as salvage therapy in those patients, replacing cisplatin with oxaliplatin in the standard dexamethasone, cytarabine, and cisplatin scheme.METHODS:Seventy patients with relapsed or refractory aggressive non‐Hodgkin or Hodgkin lymphoma were treated from September 2001 to September 2007. The median age of patients was 51 years (range, 19‐75 years). Histological subtypes were: diffuse large B‐cell lymphoma (n = 47) and Hodgkin lymphoma (n = 23). The overall response rate was 73% (51 of 70), with 30 (43%) complete remissions and 21 (30%) partial remissions. Fifty‐two patients were treated with dexamethasone, high‐dose cytarabine, and oxaliplatin as second‐line chemotherapy. Forty‐eight patients were enrolled in an autologous stem cell transplantation program; forty (83%) finally proceeded to high‐dose consolidation and autografting.RESULTS:No grade 3 or 4 nonhematological toxicity was demonstrated; in particular, no renal or neurotoxicity was reported. After a median follow‐up period of 21 months (range, 2‐87 months), 22 (31%) patients had died. Probabilities of 2‐year progression‐free survival (PFS) and overall survival (OS) were 44% and 71%, respectively. In the chemosensitive patients, the PFS and OS were 52% and 83%, respectively. The only factor that significantly correlated with better OS was the response to therapy.CONCLUSIONS:This study confirms that dexamethasone, high‐dose cytarabine, and oxaliplatin ± rituximab is an effective and feasible outpatient regimen for salvage therapy in patients affected by relapsed or refractory lymphoma. Moreover, the feasibility and efficacy of this scheme as an in vivo chemosensitive test in patients in autotransplantation programs was confirmed. Cancer 2010. © 2010 American Cancer Society.
Influence of patients' preferences and treatment site on cancer patients' end‐of‐life care
Authors: Wright Alexi A. , Mack Jennifer W. , Kritek Patricia A. , Balboni Tracy A. , Massaro Anthony F. , Matulonis Ursula A. , Block Susan D. , Prigerson Holly G. 
Published: June 2010

AbstractBACKGROUND:Research suggests that patients' end‐of‐life (EOL) care is determined primarily by the medical resources available, and not by patient preferences. The authors examined whether patients' desire for life‐extending therapy was associated with their EOL care.METHODS:Coping with Cancer is a multisite, prospective, longitudinal study of patients with advanced cancer. Three hundred one patients were interviewed at baseline and followed until death, a median of 4.5 months later. Multivariate analyses examined the influence of patients' preferences and treatment site on whether patients received intensive care or hospice services in the final week of life.RESULTS:Eighty‐three of 301 patients (27.6%) with advanced cancer wanted life‐extending therapy at baseline. Patients who understood that their disease was terminal or who reported having EOL discussions with their physicians were less likely to want life‐extending care compared with others (23.4% vs 42.6% and 20.7% vs 44.4%, respectively; P ≤ .003). Patients who were treated at Yale Cancer Center received more intensive care (odds ratio [OR], 3.14; 95% confidence interval [CI], 1.16‐8.47) and less hospice services (OR, 0.52; 95% CI, 0.29‐0.92) compared with patients who were treated at Parkland Hospital. However, in multivariate analyses that controlled for confounding influences, patients who preferred life‐extending care were more likely to receive intensive care (adjusted OR [AOR], 2.91; 95% CI, 1.09‐7.72) and were less likely to receive hospice services (AOR, 0.45; 95% CI, 0.26‐0.78). Treatment site was not identified as a significant predictor of EOL care.CONCLUSIONS:The treatment preferences of patients with advanced cancer may play a more important role in determining the intensity of medical care received at the EOL than previously recognized. Future research is needed to determine the mechanisms by which patients' preferences for care and treatment site interact to influence EOL care. Cancer 2010. © 2010 American Cancer Society.
Translating research into evidence‐based practice
Authors: Minasian Lori M. , Carpenter William R. , Weiner Bryan J. , Anderson Darrell E. , McCaskill‐Stevens Worta , Nelson Stefanie , Whitman Cynthia , Kelaghan Joseph , O'Mara Ann M. , Kaluzny Arnold D. 
Published: June 2010

AbstractThe recent rapid acceleration of basic science is reshaping both our clinical research system and our healthcare delivery system. The pace and growing volume of medical discoveries are yielding exciting new opportunities, yet we continue to face old challenges to maintain research progress and effectively translate research into practice. The National Institutes of Health and individual government programs increasingly are emphasizing research agendas that involve evidence development, comparative‐effectiveness research among heterogeneous populations, translational research, and accelerating the translation of research into evidence‐based practice as well as building successful research networks to support these efforts. For more than 25 years, the National Cancer Institute Community Clinical Oncology Program has successfully extended research into the community and facilitated the translation of research into evidence‐based practice. By describing its keys to success, this article provides practical guidance to cancer‐focused, provider‐based research networks as well as those in other disciplines. Cancer 2010. © 2010 American Cancer Society.