bluuebunny/crossref_metadata_2025_split huggingface dataset:
How valuable is a well‐crafted design and name brand?: Recognition and willingness to pay
Authors: Kristensen Tore , Gabrielsen Gorm , Zaichkowsky Judith Lynne 
Published: November 2011

ABSTRACTPreferences for similarly designed consumer products, evaluated blind and branded and also with and without prices, were tested in a consumer setting. The consumer's perceptual experience led to preference of the well‐crafted high‐priced option. This preference was enhanced by priming consumers with background information about the brand, perhaps causing the subjects to guess which choice was the well‐known brand before evaluation. Preferences for that choice increased again when brand names were visible during evaluation. When actual prices were added to the evaluations, preferences for the well‐known brand were very robust to high prices, indicating the strength of the brand name. Using the least preferred option and the lowest price as an anchor, the consumers' price threshold to pay for the preferred design and the brand name was computed. Attempts to explain and predict individual differences of choices using measures of inherent design acumen, prior experience, and purchasing behavior were largely unsuccessful. Copyright © 2011 John Wiley & Sons, Ltd.
The XIENCE nano™ everolimus eluting coronary stent system for the treatment of small coronary arteries: The SPIRIT small vessel trial
Authors: Cannon Louis A. , Simon Daniel I. , Kereiakes Dean , Jones Jennifer , Mehran Roxana , Kusano Hajime , Zhang Zhen , Lombardi William , James Fleischhauer F. , Costa Marco A. 
Published: November 2011

AbstractObjectives: The SPIRIT Small Vessel (SV) was designed to evaluate the safety and effectiveness of the 2.25‐mm XIENCE V everolimus eluting coronary stent system (EECSS), known as the XIENCE nano EECSS, in subjects with SVs and ischemic heart disease. Background: The core sizes of XIENCE V EECSS are associated with low rates of restenosis and thrombosis in the general population, but the XIENCE nano EECSS has not been tested in the United States. Methods: This prospective, single‐arm, open‐label study was conducted at 33 centers and in 150 patients in the United States. The primary endpoint was the target lesion failure (TLF) rate at 1 year, required to meet the prespecified performance goal (PG) of 20.4%, derived from historical data. Results: The mean patient age was 63 years, 38% were women, 39.2% were diabetic, 49.3% had multivessel disease, and the reference vessel diameter was 2.13 ± 0.23 mm. The 1‐year TLF rate was 8.1% in with an upper limit of the one‐sided 95% confidence interval of 13.0%, which met the PG of 20.4% (P < 0.0001). At 1 year, the rate of cardiac death was 1.5%, the target vessel myocardial infarction rate was 1.5%, and clinically indicated target lesion revascularization rate was 5.1%. The 8‐month angiographic in‐stent late loss was 0.2 ± 0.4 mm, respectively. The 1‐year academic research consortium defined definite/probable stent thrombosis rate was 1.5%. Conclusions: Based on the 1‐year clinical and 8‐month angiographic SPIRIT SV data, the XIENCE nano EECSS is considered safe and effective in the treatment of SVs. © 2011 Wiley Periodicals, Inc.
Retrograde fractional flow reserve and recanalization of a chronic total occlusion of a saphenous venous graft
Authors: Singla Sandeep , Uretsky Barry F. , Sachdeva Rajesh 
Published: November 2011

AbstractChronic total occlusion (CTO) of the coronary artery represents a difficult group of lesions for percutaneous interventions. Conventionally, antegrade approach has been used to open these lesions, but recent literature provides evidence for the utility of retrograde approach in cases where initial antegrade approach is either not feasible or fails to recanalize the target vessel. This report illustrates retrograde CTO recanalization of saphenous vein graft (SVG) with fractional flow reserve utilization to determine ischemia in the territory of occluded SVG. © 2012 Wiley Periodicals, Inc.
The prognostic role of mitral regurgitation after primary percutaneous coronary intervention for acute ST‐Elevation myocardial infarction
Authors: Uddin Ahmed M. , Henry Timothy D. , Hodges James S. , Haq Zeeshan , Pedersen Wesley R. , Harris Kevin M. 
Published: November 2011

AbstractObjectives: The aim of this study was to elucidate the prognostic significance of mitral regurgitation (MR) after primary percutaneous coronary intervention (PCI) for acute ST‐elevation myocardial infarction (STEMI). Background: MR has prognostic implications after myocardial infarction (MI). However, for STEMI patients receiving primary PCI, the influence of MR on long‐term (3–5 years) outcome is unknown. Methods: We examined 888 STEMI patients receiving primary PCI enrolled in a prospective database at a regional STEMI center, who had an echocardiogram within 72 hr following successful primary PCI. MR was graded by color Doppler as none/trace vs. mild vs. moderate/severe. Mean ± SD follow‐up was 3.1 ± 1.4 years. Results: For patients with none/trace (n = 469), mild (n = 325), and moderate/severe (n = 94) MR, mortality at 3 years was 8.1%, 13.6%, and 25.7% and at 5 years was 12.7%, 18.3%, and 33.5%, respectively (P < 0.0001, log‐rank test). Patients with moderate/severe MR tended to be older (P < 0.0001) with lower ejection fraction (P < 0.0001) and were less likely to have had an anterior MI (P < 0.001). Independent predictors of mortality included age, creatinine, and heart rate. Conclusions: Following primary PCI for STEMI, echocardiographic detected MR in the first 72 hr following PCI stratifies mortality risk. However, when accounting for age, MR is not an independent predictor of mortality. © 2011 Wiley Periodicals, Inc.
Use of intraprocedural CT imaging to guide alcohol septal ablation of hypertrophic cardiomyopathy in the cardiac catheterization laboratory
Authors: Krishnaswamy Amar , Tuzcu E. Murat , Kapadia Samir R. 
Published: November 2011

AbstractAlcohol septal ablation (ASA) is a common treatment for hypertrophic cardiomyopathy. The success of the procedure is dependent on targeting a small dose of alcohol to the appropriate septal perforator in order to cause a myocardial infarction in the septum at the point of mitral valve contact. Typically, this is identified by injecting echocardiographic contrast into a septal vessel and using echocardiography to confirm that the area of septal–systolic anterior motion contact is highlighted. Rotational angiography using the C‐arm in the catheterization laboratory acquires a 3‐dimensional “CT‐like” image, and has shown promise in providing anatomic guidance in coronary and structural heart disease interventions. We demonstrate here a novel application of intraprocedural CT imaging to localize the region of interest for ASA in the catheterization laboratory. © 2012 Wiley Periodicals, Inc.
Clinical outcome following transcatheter aortic valve implantation in patients with impaired left ventricular systolic function
Authors: van der Boon Robert M. , Nuis Rutger‐Jan , Van Mieghem Nicolas M. , Benitez Luis M. , van Geuns Robert‐Jan , Galema Tjebbe W. , van Domburg Ron T. , Geleijnse Marcel L. , Dager Antonio , de Jaegere Peter P. 
Published: November 2011

AbstractObjectives: To determine the prevalence of impaired left ventricular (LV) systolic function and its impact on the in‐hospital and long‐term outcome in patients who underwent Transcatheter Aortic Valve Implantation (TAVI). Background: Although impaired LV function may be considered a contra‐indication for aortic valve replacement, the hemodynamic characteristics of transcatheter valves may offer procedural and long‐term clinical benefit in such patients. Methods: 230 consecutive patients underwent TAVI with the Medtronic‐CoreValve System. Impaired LV function was defined by a Left Ventricular Ejection Fraction (LVEF) ≤ 35% (European Multicenter Study on Operative Risk Stratification and Long‐term Outcome in patients with Low‐Flow/Low‐Gradient Aortic Stenosis). Study endpoints were selected and defined according to the Valve Academic Research Consortium recommendations. Results: Compared with patients with a LVEF > 35% (n = 197), those with LVEF ≤ 35% (n = 33) were more often male (78.8 % vs. 46.7%, P < 0.001), more symptomatic (NYHA class III or IV, 97.0% vs. 77.2%, P = 0.008) and had a higher prevalence of prior coronary artery disease (63.6% vs. 43.1%, P = 0.029). The Logistic EuroSCORE was 14.8% and 22.8, respectively (P = 0.012). No difference was observed between the two groups in in‐hospital or 30‐day mortality (3.0% vs. 9.6%, P = 0.21), the Combined Safety Endpoint at 30 days (24.2% and 24.4%, P = 0.99) and survival free from readmission at one year (69.2% and 69.7%, P = 0.85). After adjustment, LVEF ≤ 35% was not associated with an increased risk of 30‐day mortality, in‐hospital complications and survival free from readmission at follow‐up. Conclusion: The immediate and long‐term outcome after TAVI did not differ between patients with an impaired and preserved LVEF. LVEF ≤ 35% did not predict adverse immediate and long‐term outcome. These findings suggest that TAVI should not be withheld in selected patients with impaired LV function. © 2011 Wiley Periodicals, Inc.
Anatomic features of the left main coronary artery and factors associated with its bifurcation angle: A 3‐dimensional quantitative coronary angiographic study
Authors: Rubinshtein Ronen , Lerman Amir , Spoon Daniel B. , Rihal Charanjit S. 
Published: November 2011

AbstractObjective: To assess the anatomic characteristics of the left main coronary artery (LM), and the relation between anatomic and clinical factors and the LM bifurcation angle (BA) using a novel, three dimensional quantitative coronary angiography (3D QCA) software. Background: Percutaneous intervention of the LM is a therapeutic option in selected patients with coronary artery disease (CAD). The anatomic features of the LM and its BA are determinants of procedural success and clinical outcome. However, those features and the factors that may affect the LM BA have not been fully described. Methods: The LM anatomy was evaluated from angiograms of 203 patients (age = 66 ± 11 years, 31% female) with and without LM CAD using 3D QCA analysis (IC‐PRO, Paieon, Israel). LM size as well as the proximal BA (between LM and LCX) and the distal BA (between left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX)) were measured in end‐diastole. Angiographic and clinical findings were also recorded. Results: 133/203 patients (65%) had no LM CAD. 3D QCA analysis demonstrated significant variability in the anatomy of the normal LM, including the LM branch vessels (LAD, LCX) diameter, and the LM BA. Among the 70 patients with LM CAD, 44 had distal LM disease. Importantly, patients with distal LM CAD had narrower proximal BA and a wider distal BA. Multivariate analysis (adjusted for clinical and anatomic variables) identified female sex (P = 0.02), trifurcation anatomy (P = 0.009), age > 75 years (P = 0.0009), and LM length > 12 mm (P = 0.001) as independent associates of the proximal BA. Independent associates of the distal BA were: trifurcation anatomy (P = 0.001), LM length > 12 mm (P < 0.0001), age > 75 years (P = 0.004), and a history of coronary bypass surgery (P = 0.04). Conclusions: The current study demonstrates significant variability in the anatomy of the LM. The LM BA differs between patients with and without distal LM CAD, and both anatomic and clinical factors may affect the LM BA. Our findings also emphasize the possible usefulness of 3D QCA in the assessment of the LM. © 2012 Wiley Periodicals, Inc.
Retrograde transpedal stenting of the tibioperoneal trunk in critical limb ischemia
Authors: Ruzsa Zoltán , Pintér László , Kolvenbach Ralf 
Published: November 2011

AbstractManagement of critical limb ischemia (CLI) requires a combined treatment approach: optimal medical therapy and revascularization procedures are both essential for favorable outcome. With the development of endovascular interventions these new modalities took the primary role in limb revascularization, especially in CLI patients, where the culprit lesion is often located below the knee (BTK) level, making the surgical procedure unfeasible. In our present case report, we demonstrate a successful percutaneous recanalization of a surgically non‐treatable tibioperoneal trunk occlusion. The procedure was performed with dual access from anterograde and retrograde transpedal approach, and modified “V stenting” technique was used. We describe feasibility of bail out stenting using retrograde posterior tibial artery access after failed retrograde guidewire externalization. Our report discusses the feasibility, safety, and efficacy of the retrograde approach applying 4F compatible devices. © 2012 Wiley Periodicals, Inc.
Use of four MitraClip devices in a patient with ischemic cardiomyopathy and mitral regurgitation
Authors: Kische Stephan , Nienaber Christoph , Ince Hüseyin 
Published: November 2011

AbstractSevere mitral regurgitation (MR) as a consequence of underlying left ventricular dysfunction substantially contributes to morbidity and mortality. A variety of percutaneous treatment options for mitral valve repair have been developed; however, most of these techniques are still at an early stage of clinical evaluation. Today, percutaneous edge‐to‐edge mitral valve repair using the MitraClip® system is the only endovascular approach that demonstrated noninferiority when compared with standard surgical repair in a randomized trial. However, a considerable number of patients with functional MR will present with extensive annulus dilatation and minimal vertical leaflet coaptation that potentially preclude them from this beneficial technology for anatomical reasons. In this report, we portray a 72‐year‐old man presenting with end‐stage systolic heart failure and severe functional MR as a consequence of long‐standing coronary artery disease. Recently, his clinical course was complicated by intractable hemodynamic instability and recurrent pulmonary edema. High predicted mortality and progressive physical decay rendered this moribund patient a candidate for salvage percutaneous mitral valve repair. During the endovascular procedure, a central systolic coaptation gap of 7 mm proved to be too wide for adequate simultaneous grasping of both leaflets. Consideration was given to an alternative approach by means of our novel “zipping technique.” Through the trans‐septal route, medial to lateral approximation of the tethered leaflets was successfully achieved by intentional deployment of four MitraClip® devices. With the first in‐human application of four mechanical implants, a profound reduction of MR grade has been accomplished by the creation of a lateral neo‐orifice with apparent acute clinical success. However, it needs to be determined whether successful application of the zipping technique leads to sustained reverse ventricular remodeling and will translate into an improved long‐term prognosis. © 2012 Wiley Periodicals, Inc.
Elective percutaneous intervention for intracranial atherosclerotic stenoses by interventional cardiologists
Authors: Badawi Ramy A. , White Christopher J. , Collins Tyrone J. , Jenkins J. Stephen , Reilly John P. , Grise Mark A. , McMullan Paul W. , Ramee Stephen R. 
Published: November 2011

AbstractBackground: Current “best” medical therapy with anti‐platelet and/or anti‐thrombotic agents for symptomatic atherosclerotic intracranial (IC) disease is associated with high recurrence. IC catheter‐based therapy (CBT) using balloon angioplasty with or without stent placement is an option for patients who have failed medical therapy. We sought to examine the outcomes of CBT for patients with symptomatic IC arterial disease managed by experienced interventional cardiologists. Methods: We retrospectively studied 89 consecutive symptomatic patients with 99 significant (≥70% diameter) IC arterial stenoses who underwent CBT. CBT was performed by experienced interventional cardiologists with the consultative support of a neurovascular team. The primary endpoint was stroke and vascular death. Results: Procedure success was achieved in 96/99 (97%) lesions and percent diameter stenosis was reduced from 91% ± 7.5% preprocedure to 19% ± 15% postprocedure (P < 0.001). The rate of in‐hospital periprocedural stroke and all death was 3%. The primary endpoint of stroke and vascular death rate at 1 year was 5.7% (5/88) and at 2 years was 13.5% (11/81). The 2‐year all‐cause mortality was 11.3% (10/88). Conclusions: For patients with symptomatic IC arterial stenosis who have failed medical therapy or are considered very high risk for stroke, CBT performed by experienced interventional cardiologists is safe and offers both high procedural success rates and excellent clinical outcomes at 1 year. CBT is an attractive option for this high‐risk patient population considering the expected 12–15% rate of recurrent stroke at 1 year. © 2012 Wiley Periodicals, Inc.
Comparison of the efficacy and safety of paclitaxel‐eluting coroflex please stents and paclitaxel‐eluting stents in patients with coronary artery disease: A randomized PIPA trial
Authors: Kim Hyun‐Sook , Park Seung‐Jung , Park Duk‐Woo , Park Seong‐Wook , Cheong Sang‐Sig , Lee Sang‐Gon , Cho Byung‐Ryul , Lee Seung‐Wook , Lee Nae‐Hee , Lee Keun ,   for the PIPA Study Investigators
Published: November 2011

AbstractObjectives: To compare the safety and efficacy of the new Coroflex™ Please stents with conventional Taxus™ Liberte stents in patients with coronary artery lesions. Background: The Coroflex™ Please stent is a new version of paclitaxel‐eluting stent, and observational cohort studies have reported similar angiographic and clinical outcomes as with the first‐generation stents. However, it has not been directly compared with the early generation paclitaxel‐eluting stents in a multicenter, prospective, and randomized study. Methods: We randomly assigned 319 patients to receive Coroflex™ Please stents (159 patients; 198 lesions) or Taxus™ Liberte stents (160 patients; 232 lesions). The primary end point was angiographic in‐segment late luminal loss at 9 months. Results: Most baseline clinical and angiographic characteristics were similar between these two groups. The Coroflex™ Please and Taxus™ Liberte stents showed similar in‐segment late loss (0.40 ± 0.53 mm vs. 0.39 ± 0.52 mm, P = 0.98) and rates of in‐segment binary restenosis (22.2% vs. 18.8%, P = 0.48) at 9 months. After clinical follow‐up for 12 months, the two groups had similar rates of death (1.3% vs. 1.3%, P > 0.99), myocardial infarction (3.8% vs. 7.5%, P = 0.22), stent thrombosis (2.5% vs. 1.9%, P = 0.72), and target‐lesion revascularization (7.5% vs. 7.5%, P = 0.99). Conclusions: The Coroflex™ Please stent resulted in similar angiographic and clinical outcomes as the Taxus™ Liberte stent in patients with coronary artery lesions. © 2012 Wiley Periodicals, Inc.
One + One‐Dimensional Modeling of Monolithic Catalytic Converters
Authors: Depcik C. , Srinivasan A. 
Published: November 2011

AbstractThe inclusion of a washcoat model into monolithic catalyst simulations in order to create a one + one‐dimensional framework using a minimum number of parameters is reviewed. All assumptions and numerical methods are presented while ensuring the prevention of excessive temperature excursions. Parametric studies illustrate the influence of model parameters (porosity, wall thickness, pore diameter) on the conversion of carbon monoxide during a light‐off experiment using a uniform washcoat. Moreover, simulating a layered washcoat of dissimilar catalytic materials demonstrates a significant influence on conversion characteristics depending on the order of the layers. As a result, employing a washcoat requires careful consideration of the advection of the gas, the reactions occurring in each catalytic material, material layering, the diffusion properties of the different species, and the characteristics of the washcoat.
CFD Prediction of the Critical Agitation Speed for Complete Dispersion in Liquid‐Liquid Stirred Reactors
Authors: Cheng D. , Cheng J. , Yong Y. , Yang C. , Mao Z.‐S. 
Published: November 2011

AbstractA computational fluid dynamics (CFD) model is adopted to simulate the turbulent immiscible liquid‐liquid flow in a stirred vessel based on a two‐fluid model with a k‐ϵ‐AP turbulence model. An improved inner‐outer iterative procedure is adopted to deal with the impeller rotation in a fully baffled stirred tank. Different drag formulations are examined, and the effect of the droplet size on both the dispersed phase holdup distribution and the velocity field is analyzed. Two different numerical criteria are tested for determining the critical impeller speed for complete dispersion. The simulated critical impeller speeds are generally in good agreement with the correlations in the literature when the fixed droplet size is properly selected. This demonstrates that the modeling approach and the numerical criteria proposed in this work are promising for predicting the dispersion characteristics in liquid‐liquid stirred tanks.
Heat Exchanger Network Integration Considering Flow Exergy Loss
Authors: Jiang N. , Li L. 
Published: November 2011

AbstractThis work describes a systematic procedure to integrate a heat exchanger network (HEN) considering heat and flow exergy consumptions. The flow exergy consumption by the HEN is calculated by means of pressure drop correlation and stepwise optimization. Case studies reveal that the flow exergy loss changes the two‐way trade‐off between the operating cost and the capital cost in the traditional method. The introduction of heat exergy loss adds the weight of energy cost by considering both the external utility consumption and internal heat exergy loss in the HEN, which benefits heat recovery and energy conservation at the cost of more area and investment. In contrast, the flow exergy loss shifts the balance to the capital cost by adding the cost relating to area in terms of flow frictional dissipation.
Development of Al2O3 Film on Diatomite for Treating Wastewater Containing Anionic Polyacrylamide
Authors: Zhang Y. , Zhang C. , Zhang Y. , Zhang G. , Liu S. , Xu Z. 
Published: November 2011

AbstractTo efficiently treat anionic polyacrylamide (APAM) with a linear structure in wastewater, an Al2O3 film on the surface of diatomite was prepared via the hydrolysis reaction of AlCl3. The Al2O3‐coated diatomite was characterized by FT‐IR, XRD, and SEM. The results show that the Al2O3 film can be coated on diatomite. The resulting Al2O3‐coated diatomite was utilized to treat wastewater (pH = 7) that contained APAM of 60 mg L–1 and suspended solids of 90 mg L–1. Results show that after wastewater was treated using Al2O3‐coated diatomite, the content of APAM and suspended solids in the filtrate can meet the standard for wastewater recycling. Therefore, Al2O3‐coated diatomite can be used in treating wastewater containing APAM.
Partially Acetylated Sugarcane Bagasse for Wicking Oil from Contaminated Wetlands
Authors: Chung S. , Suidan M. T. , Venosa A. D. 
Published: November 2011

AbstractSugarcane bagasse was partially acetylated to enhance its oil‐wicking ability in saturated environments while holding moisture for hydrocarbon biodegradation. The water sorption capacity of raw bagasse was reduced fourfold after treatment, which indicated considerably increased hydrophobicity but not a limited capability to hold moisture for hydrocarbon biodegradation. Characterization results by Fourier transform infrared (FT‐IR), scanning electron microscopy (SEM), X‐ray diffraction (XRD), and surface area analyzer suggested that treated bagasse exhibited enhanced hydrophobicity and surface area. Oil wicking test results indicate that treated bagasse is more effective in wicking oil from highly saturated environments than raw bagasse and suggest that application of this material in remediation of oil spills in highly saturated wetlands is promising.