bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presence of herpesviruses, parvoviruses, and polyomaviruses in sinonasal lymphoma
Authors: Jauhiainen Maria K. , Mohanraj Ushanandini , Perdomo Maria F. , Hagström Jaana , Haglund Caj , Mäkitie Antti A. , Söderlund-Venermo Maria , Sinkkonen Saku T. 
Published: May 2024

Abstract
Purpose
Sinonasal lymphoma (SL) is a rare lymphatic neoplasm of the nasal cavities, paranasal sinuses and nasopharynx. Whereas some risk factors for SL subtypes have been identified, their aetiology is unknown. Along with other predisposing factors, the viral association of lymphomas, such as Epstein-Barr virus (EBV) and Burkitt and Hodgkin lymphomas, is well-established. Modern molecular biology techniques have enabled the discovery of novel human viruses, exemplified by the protoparvovirus cutavirus (CuV), associated with cutaneous T-cell lymphoma. These findings, and the anatomical location of the sinonasal tract with its rich microbiome and infectious agents, justify in-depth studies among SL.

Methods
We analysed the presence of 20 viruses of Orthoherpesviridae, Parvoviridae, and Polyomaviridae by qPCR in 24 SL tumours. We performed RNAscope in situ hybridisation (RISH) to localize the viruses. Parvovirus-specific IgG was analysed by enzyme immunoassay and targeted next-generation sequencing (NGS) was applied to detect CuV in plasma.

Results
We detected viral DNA in 15/24 (63%) tumours; nine of EBV, six of human herpesvirus (HHV) -7, four each of HHV-6B and parvovirus B19, two of cytomegalovirus, and one each of CuV and Merkel-cell polyomavirus. We found tumours with up to four viruses per tumour, and localized CuV and EBV DNAs by RISH. Two of the ten plasma samples exhibited CuV IgG, and one plasma sample demonstrated CuV viremia by NGS.

Conclusion
Viruses were frequent findings in SL. The EBV detection rate was high in diffuse large B-cell lymphoma, and co-detections with other viruses were prevalent.
DNA choreography: correlating mobility and organization of DNA across different resolutions from loops to chromosomes
Authors: Pabba Maruthi K. , Meyer Janis , Celikay Kerem , Schermelleh Lothar , Rohr Karl , Cardoso M. Cristina 
Published: May 2024

AbstractThe dynamics of DNA in the cell nucleus plays a role in cellular processes and fates but the interplay of DNA mobility with the hierarchical levels of DNA organization is still underexplored. Here, we made use of DNA replication to directly label genomic DNA in an unbiased genome-wide manner. This was followed by live-cell time-lapse microscopy of the labeled DNA combining imaging at different resolutions levels simultaneously and allowing one to trace DNA motion across organization levels within the same cells. Quantification of the labeled DNA segments at different microscopic resolution levels revealed sizes comparable to the ones reported for DNA loops using 3D super-resolution microscopy, topologically associated domains (TAD) using 3D widefield microscopy, and also entire chromosomes. By employing advanced chromatin tracking and image registration, we discovered that DNA exhibited higher mobility at the individual loop level compared to the TAD level and even less at the chromosome level. Additionally, our findings indicate that chromatin movement, regardless of the resolution, slowed down during the S phase of the cell cycle compared to the G1/G2 phases. Furthermore, we found that a fraction of DNA loops and TADs exhibited directed movement with the majority depicting constrained movement. Our data also indicated spatial mobility differences with DNA loops and TADs at the nuclear periphery and the nuclear interior exhibiting lower velocity and radius of gyration than the intermediate locations. On the basis of these insights, we propose that there is a link between DNA mobility and its organizational structure including spatial distribution, which impacts cellular processes.
Physical work environment in an activity-based flex office: a longitudinal case study
Authors: Wahlström Viktoria , Öhrn Maria , Harder Mette , Eskilsson Therese , Fjellman-Wiklund Anncristine , Pettersson-Strömbäck Anita 
Published: May 2024

Abstract
Objective
This study aimed to investigate and explore Occupational Health and Safety (OHS) management, office ergonomics, and musculoskeletal symptoms in a group of office workers relocating from cell offices to activity-based flex offices (AFOs).

Methods
The analysis was based on qualitative interview data with 77 employees and longitudinal questionnaire data from 152 employees.

Results
Results indicate that there was a need to clarify roles and processes related to the management of OHS. Self-rated sit comfort, working posture, and availability of daylight deteriorated and symptoms in neck and shoulders increased after the relocation and seemed to be influenced by many factors, such as difficulties adjusting the workstations, the availability of suitable workplaces, and age, sex, and individual needs.

Conclusion.
Research on the long-term effects of physical work environments and management of (OHS) issues after implementing activity-based flex offices is sparse. This study demonstrates the importance of planning and organising OHS issue management when implementing an AFO, and to carefully implement office ergonomics among office workers.
Release of Angiostrongylus cantonensis larvae from live intermediate hosts under stress
Authors: Šipková Anna , Anettová Lucia , Izquierdo-Rodriguez Elena , Velič Vivienne , Modrý David 
Published: May 2024

AbstractThe metastrongyloid nematode Angiostrongylus cantonensis causes eosinophilic meningitis in a variety of homeothermic hosts including humans. Third-stage infectious larvae develop in gastropods as intermediate hosts. Humans are usually infected by intentional or incidental ingestion of an infected mollusk or paratenic host (poikilothermic vertebrates and invertebrates). The infection may also hypothetically occur through ingestion of food or water contaminated by third-stage larvae spontaneously released from gastropods. Larvae are thought to be released in greater numbers from the intermediate host exposed to stress. This study aimed to compare larval release from stressed with unstressed gastropods. Experimentally infected Limax maximus and Lissachatina fulica were exposed to a stress stimulus (shaking on an orbital shaker). The mucus was collected before and after the stress and examined microscopically and by qPCR for the presence of A. cantonensis larvae and their DNA. In the case of L. maximus, no larvae were detected microscopically in the mucus, but qPCR analysis confirmed the presence of A. cantonensis DNA in all experimental replicates, without clear differences between stressed and non-stressed individuals. In contrast, individual larvae of A. cantonensis were found in mucus from Li. fulica after stress exposure, which also reflects an increased number of DNA-positive mucus samples after stress. Stress stimuli of intensity similar to the transport or handling of mollusks can stimulate the release of larvae from highly infected intermediate hosts. However, these larvae are released in small numbers. The exact number of larvae required to trigger neuroangiostrongyliasis is unknown. Therefore, caution is essential when interacting with potential intermediate hosts in regions where A. cantonensis is endemic.
Biochar is colonized by select arbuscular mycorrhizal fungi in agricultural soils
Authors: Neuberger Patrick , Romero Carlos , Kim Keunbae , Hao Xiying , A. McAllister Tim , Ngo Skyler , Li Chunli , Gorzelak Monika A. 
Published: May 2024

AbstractArbuscular mycorrhizal fungi (AMF) colonize biochar in soils, yet the processes governing their colonization and growth in biochar are not well characterized. Biochar amendment improves soil health by increasing soil carbon, decreasing bulk density, and improving soil water retention, all of which can increase yield and alleviate environmental stress on crops. Biochar is often applied with nutrient addition, impacting mycorrhizal communities. To understand how mycorrhizas explore soils containing biochar, we buried packets of non-activated biochar in root exclusion mesh bags in contrasting agricultural soils. In this greenhouse experiment, with quinoa (Chenopodium quinoa) as the host plant, we tested impacts of mineral nutrient (as manure and fertilizer) and biochar addition on mycorrhizal colonization of biochar. Paraglomus appeared to dominate the biochar packets, and the community of AMF found in the biochar was a subset (12 of 18) of the virtual taxa detected in soil communities. We saw differences in AMF community composition between soils with different edaphic properties, and while nutrient addition shifted those communities, the shifts were inconsistent between soil types and did not significantly influence the observation that Paraglomus appeared to selectively colonize biochar. This observation may reflect differences in AMF traits, with Paraglomus previously identified only in soils (not in roots) pointing to predominately soil exploratory traits. Conversely, the absence of some AMF from the biochar implies either a reduced tendency to explore soils or an ability to avoid recalcitrant nutrient sources. Our results point to a selective colonization of biochar in agricultural soils.
Kybernetik dritter Ordnung? Entwicklung einer phänomenologisch angesetzten Theoriebildung und ihre Relevanz für die systemtherapeutische Praxis und Lehre
Authors: Niel-Dolzer Evelyn 
Published: May 2024

ZusammenfassungMit Ludwik Flecks Konzept des Denkstils wird ein Vorschlag unterbreitet, Theoriebestände innerhalb eines zersplitterten Binnendiskurses hinsichtlich ihrer klinischen Nützlichkeit explizit(er) herauszuarbeiten. Anhand einer konkreten Entwicklung in der Lehranstalt für Systemische Familientherapie wird gezeigt, wie der Wechsel von einem konstruktivistisch zu einem phänomenologisch fundierten Bezugsrahmen eine Alternative zur Polarisierung von Subjekttheorien und Theorien sozialer Systeme darstellt: Aus der Perspektive der Intersubjektivität lässt sich psychisches Erleben systemtheoretisch fundiert konzeptualisieren, theoriegeleitet beobachten und in der Ausbildung vermitteln. Anschlüsse und Beteiligung an schulenübergreifenden Diskursen als Anspruch an eine zeitgemäße Ausbildung werden sichtbar gemacht.
Implementation and optimization of Burg’s method for real-time packet loss concealment in networked music performance applications
Authors: Sacchetto Matteo , Rottondi Cristina , Bianco Andrea 
Published: May 2024

AbstractIn networked music performance (NMP) applications, which entail real-time audio streaming over the Internet, strict latency requirements are needed to ensure a realistic interaction between geographically dispersed musicians. Thus, NMP applications typically leverage uncompressed audio and unreliable transport protocols to avoid unnecessary processing and re-transmission delays. Given that no guarantee on packet delivery is offered, NMP applications must deal with late/lost audio packets to mitigate the impact of the resulting audio artifacts on the quality of the playback audio stream. This paper explores an audio packet loss concealment (PLC) technique based on autoregressive (AR) models. In particular, it investigates the algorithmic implementation of Burg’s method and the parameters configuration that offers the best trade-off between prediction error and computational time requirements. The purpose is to find the most suitable solution capable of running on a Raspberry Pi 4B within the real-time audio boundaries imposed by NMP applications. Additionally, we analyze the computational time required to fit the model and predict future samples by considering six implementations and various compilation flags. Results confirm that AR models can predict future audio samples more accurately than traditional PLC approaches, which consist of filling audio gaps with silence or repeating the last received audio segment. Furthermore, results demonstrate the effectiveness of the proposed solution in meeting the strict latency requirements when deployed on a Raspberry Pi 4B.
Replicating outdoor environments using VR and ambisonics: a methodology for accurate audio-visual recording, processing and reproduction
Authors: Georgiou Fotis , Kawai Claudia , Schäffer Beat , Pieren Reto 
Published: May 2024

AbstractThis paper introduces a methodology tailored to capture, post-process, and replicate audio-visual data of outdoor environments (urban or natural) for VR experiments carried out within a controlled laboratory environment. The methodology consists of 360$$^\circ$$

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video and higher order ambisonic (HOA) field recordings and subsequent calibrated spatial sound reproduction with a spherical loudspeaker array and video played back via a head-mounted display using a game engine and a graphical user interface for a perceptual experimental questionnaire. Attention was given to the equalisation and calibration of the ambisonic microphone and to the design of different ambisonic decoders. A listening experiment was conducted to evaluate four different decoders (one 2D first-order ambisonic decoder and three 3D third-order decoders) by asking participants to rate the relative (perceived) realism of recorded outdoor soundscapes reproduced with these decoders. The results showed that the third-order decoders were ranked as more realistic.
The role of household labour for sustainable intensification in smallholder systems: a case study in cocoa farming systems
Authors: Tennhardt Lina M. , Lazzarini Gianna A. , Schader Christian , Martin Kagimu , Lambin Eric F. 
Published: May 2024

AbstractSustainable agricultural intensification aims at increasing yields on existing agricultural land without negative environmental impacts. Managing pests and diseases contributes to increasing yields. Without synthetic pesticides, this management is labour intensive. Smallholder farming systems heavily rely on manual and household labour, which will be affected by future demographic changes. Knowledge on how these changes will affect sustainable intensification is limited. Based on a case study of Ugandan cocoa farms, we tested the impact of increased household labour availability on pest and disease management (PDM) practices and pesticide use. We made use of a unique quasi-experimental design, in which household labour increased during the national COVID-19 lockdowns as children did not attend school and family members returned from cities. Our interview data from 2019 to 2021 showed that household labour availability increased on average by 0.8 (±2.5) household members and 16% of labour days per hectare. Using different regression models complemented with qualitative insights, we found that the uptake of alternative PDM practices significantly reduced pesticide quantities and expenditures. The implementation of alternative PDM practices was only weakly influenced by household labour availability and increased with farmer training and trust in alternative practices. These results imply that alternative PDM practices are an important pillar for production with little or without synthetic pesticides and their adoption requires support and incentives, especially on labour or resource-constrained farms.
Feasibility of 3 Tesla MRI for the assessment of mid-palatal suture maturation: a retrospective pilot study
Authors: Willershausen Ines , Kopp Markus , Scholz Michael , Ströbel Armin , Seidel Corinna Lesley , Paulsen Friedrich , Uder Michael , Gölz Lina , May Matthias Stefan 
Published: May 2024

AbstractThe maxilla occupies a key position in dentofacial orthopaedics, since its transversal development can be directly influenced by orthodontic therapy. The maturation stages of the mid-palatal suture, which are obtained from cone-beam computed tomography images (CBCT), present an addition to clinical decision-making in transversal discrepancies of the upper jaw. In an endeavour to reduce ionizing radiation in adolescents and young adults, who are particularly susceptible to long term stochastic irradiation effects, we investigated the feasibility of 3 Tesla (3T) MRI in detecting the maturation stages of the mid-palatal suture. A collective of 30 patients aged 24–93 years with routine neck MRI at 3T, underwent an additional three-dimensional isotropic T1 weighted study sequence of the midface. Image evaluation was performed on axial, multi-planar formatted reconstructions of the dataset aligned to the midline axis of the palate, and curved reconstructions aligned to the concavity of the palate. Inverted images helped to achieve an image impression similar to the well-known CBCT appearance. All datasets were reviewed by three readers and mid-palatal maturation was scored twice according to Angelieri et al. Intra- and inter-rater agreement were evaluated to measure the robustness of the images for clinical evaluation. 3T MRI deemed reliable for the assessment of mid-palatal suture maturation and hence for the appraisal of the hard palate and its adjacent sutures. The data of this pilot study display the feasibility of non-ionizing cross-sectional MRI for the determination of sutural maturation stages. These findings underline the potential of MRI for orthodontic treatment planning, further contributing to the avoidance of unnecessary radiation doses.
The death of the Empress Elisabeth of Austria and Queen of Hungary—retold and reassessed with reconstruction of her autopsy
Authors: Sedivy Roland 
Published: May 2024

SummaryIn this publication 125 years after the violent death of the famous Empress Elisabeth (1837–1898) of Austria, known as Sisi, a modern evaluation as well as valuation will be presented. The day after her assassination by the young anarchist Luigi Lucheni using a file, a partial autopsy was performed to find out the exact cause of death—a pericardial tamponade. The complete translation of the autopsy report is part of this article, the intention being to avoid unclear wording and translation errors, which have often caused some confusion in the past. A pictorial illustration of the puncture canal will provide clarity through medical facts as to how Empress Elisabeth’s death came about by correct pathological and anatomical description and, thus, counteract former interpretations.
Landscape matrix and substrate jointly shape the trait composition of true bug (Heteroptera) communities in drainage ditches
Authors: Šeat Jelena , Torma Attila , Bátori Zoltán , Popović Miloš , Tölgyesi Csaba 
Published: May 2024

AbstractDrainage ditches play a key role in the conservation of fragmented landscapes by providing refuge sites and secondary habitats for many terrestrial and aquatic organisms across various taxa. Species richness of ditches can exceed that of adjacent natural habitats, but here, we looked further and assessed the role of drainage ditches in shaping the community structure of true bugs aiming to better estimate ditches’ conservation value from the point of their species and trait composition. We tested the effects of the ditch substrate (saline, sandy or fen), landscape matrix (agrarian or grassland) and vegetation (species richness of all plants and invasive plants, and abundance of woody plants) on the true bug communities of 60 drainage ditches in the lowland of East-Central Europe. We found that substrate and landscape matrix contributed the most in determining true bug communities. Based on species composition, different substrates and landscape matrix types had distinct communities, but the trait composition showed differentiation according to the landscape matrix in saline habitats only. The trait composition in true bug communities was more diverse in grassland ditches than in agrarian ones, which hosted more habitat generalists associated with invasive vegetation. We concluded that a pronounced gradient in habitat stress, originating in substrate salinity and aridity, causes the differentiation of the true bug communities based on their trait composition. Additionally, intense habitat stress increases the number of habitat specialists and the conservation value of a drainage ditch.
Surveillance capitalism and the surveillance state: a comparative institutional analysis
Authors: Alshamy Yahya , Coyne Christopher J. , Hall Abigail R. , Owens Matthew A. 
Published: May 2024

AbstractWhat is the connection between mass surveillance and institutions of individual agency, freedom, and self-governance? Recent literature on “surveillance capitalism” argues that, over the past two decades, the capitalist Big Tech companies have commodified personal data for profit. This commodification goes beyond gathering information to improve the products provided by the collecting organization directly and entails using data to predict what people will do, the sale of that data, and its use to modify the behaviors of unknowing consumers. According to critics, this erodes individual dignity and freedom while also threatening democracy. This paper offers an alternative framing of surveillance and data collection based on comparative institutional analysis. While data collection and attempts at persuasion are present in private and government settings, the welfare effects vary due to institutional differences. We leverage the comparative institutional framework to analyze the differences between private data collection (“surveillance capitalism”) and government data collection (the “surveillance state”). Our analysis sheds light on how data collection in the private, for-profit sector has different welfare consequences from those in the surveillance state.
“Can I have it non-personalised?” An Empirical Investigation of Consumer Willingness to Share Data for Personalized Services and Ads
Authors: Leszczynska M. , Baltag D. 
Published: May 2024

AbstractEuropean regulators, courts, and scholars are currently debating the legality of data processing for personalization purposes. Should businesses require separate consent for processing user data for personalized advertising, especially when offering free services reliant on such ads for revenue? Or is general consent for the contract enough, given personalized advertising’s role in fulfilling contractual obligations? This study investigates whether these legal distinctions reflect differences in people’s willingness to share data with businesses for personalization. Are consumers less willing to share their data for personalized advertising than for personalized services that they clearly contracted for? Does that change if the service is offered for free? Drawing from both the privacy calculus and privacy as contextual integrity theory, the hypothesis posits that individuals would be more inclined to share their data when it is used to personalize the services offered by businesses (e.g., music or news recommendations) rather than for personalized advertising, yet this difference will be smaller when services are offered for free. Using three vignette experiments involving music, shopping, and news services (N = 3,436), the study demonstrates that, contrary to predictions, most individuals are hesitant to share their data for personalization, regardless of whether it’s for advertisements or contracted services. This absence of distinction persists across both paid and free services. The findings strongly support the claim that if the law considers people’s reluctance to share personal data, both personalized advertising and personalized contracted services should require separate consent to data processing from consumers.