bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Regioselective Synthesis of Flavone Derivatives via DMAP‐Catalyzed Cyclization of o‐Alkynoylphenols.
Authors: Yoshida Masahito , Fujino Yuta , Saito Koya , Doi Takayuki 
Published: March 2012

AbstractDMAP as catalyst and DMF as solvent are found to be optimal for the exclusive formation of 6‐endo products.
ChemInform Abstract: Unusually Mild and Efficient Synthesis of Functionalized Spiro‐Substituted 1,2,3,4‐Tetrahydronicotinamides by the Michael Reaction.
Authors: Dyachenko V. D. , Dyachenko I. E. 
Published: March 2012

AbstractThe mechanism for the tranformation of the nitrile group into an amide and the biological properties of title compounds (III) are under investigation.
ChemInform Abstract: New Approach to the Synthesis of 4‐Aryl‐3,5‐dicyano‐6‐oxo‐1,4,5,6‐tetrahydropyridin‐2‐olates (Salts of Guareschi Imides).
Authors: Chigorina E. A. , Dotsenko V. V. , Krivokolysko S. G. 
Published: March 2012

AbstractThe method is efficient procedure for the synthesis of 4‐aryl substituted Guareschi imides.
ChemInform Abstract: Synthesis and Pharmacological Evaluation of 1‐Alkyl‐N‐ [(1R)‐1‐(4‐fluorophenyl)‐2‐methylpropyl]piperidine‐4‐carboxamide Derivatives as Novel Antihypertensive Agents.
Authors: Watanuki Susumu , Matsuura Keisuke , Tomura Yuichi , Okada Minoru , Okazaki Toshio , Ohta Mitsuaki , Tsukamoto Shin‐ichi 
Published: March 2012

AbstractSynthesis, SAR, and pharmacological properties of a novel class of antihypertensive agents are described.
ChemInform Abstract: Solvent‐Free Microwave‐Assisted Synthesis of Substituted Pyridines Using NH4OAc as Nitrogen Source.
Authors: Trilleras Jorge , De La Torre Pedro , Pacheco Dency J. , Quiroga Jairo , Nogueras Manuel , Cobo Justo 
Published: March 2012

AbstractThe compounds (III) are synthesized by a tandem Claisen—Schmidt condensation/ Michael addition reaction.
ChemInform Abstract: BF3·Et2O and Trifluoroacetic Acid/Triethyl Amine Mediated Synthesis of Functionalized Piperidines.
Authors: Mohite Amar R. , Sultane Prakash R. , Bhat Ramakrishna G. 
Published: March 2012

AbstractThe diastereoselective synthesis of trans‐substituted piperidine derivatives (II) is achieved by N‐deprotection of esters (I) with TFA followed by NEt3‐mediated intramolecular aza‐Michael addition.
ChemInform Abstract: Quinolone Dimers as Potential Antibacterial Agents.
Authors: Chepyala Naveenkumar R. , Durgi Rajashaker R. , Tatini Lakshmi K. , Subbaraju Gottumukkala V. , Hindupur Rama M. , Dhanvada Muralimohan R. 
Published: March 2012

AbstractThe compounds (IV), (V), and (VIII) are tested in vitro for their activity against the Gram‐negative bacteria E.
ChemInform Abstract: A Concise One‐Pot Approach to the Synthesis of 4‐(1H‐Indol‐3‐yl)quinolines.
Authors: Arcadi Antonio , Chiarini Marco , Marinelli Fabio , Picchini Silvia 
Published: March 2012

AbstractThe synthesis of title compounds (III) involves the conjugate addition reaction of NaI to alkynes (I) followed by cyclization to give 2‐arylated 4‐iodoquinoline intermediates which undergo Pd‐catalyzed reaction with the ortho‐(trifluoroacetylamino)aryl substituted alkynes (II).
ChemInform Abstract: Synthesis of Quinolines Involving Electrophilic Amination of Arenes with Sodium Azide in Polyphosphoric Acid.
Authors: Lyakhovnenko A. S. , Kugutov M. M. , Aksenov A. V. 
Published: March 2012

AbstractUsing the reagent combination sodium azide/polyphosphoric acid, this one‐pot, consecutive reaction of sodium azide and dicarbonyl compounds (II) with an aromatic compound (I) affords the quinolines (III) in low to moderate yields.
ChemInform Abstract: An Efficient Synthesis of 4‐Arylquinolin‐2(1H)‐ones and 3‐Alkenyl‐4‐arylquinolin‐2(1H)‐one Using a Pd/NiFe2O4‐Catalyzed Consecutive Heck Reaction.
Authors: Borhade Sanjay R. , Waghmode Suresh B. 
Published: March 2012

AbstractThe synthesis of title arylquinolinones (IV) and the corresponding coumarin derivatives (XI) is achieved by consecutive Heck reaction of o‐iodoanilines (I) and o‐iodophenol (X), resp., with acrylic acid (II) and aryl iodides (III) in the presence of Pd—NiFe2O4 as catalyst.
ChemInform Abstract: Graphene Oxide and Rose Bengal: Oxidative C—H Functionalization of Tertiary Amines Using Visible Light.
Authors: Pan Yuanhang , Wang Shuai , Kee Choon Wee , Dubuisson Emilie , Yang Yuanyong , Loh Kian Ping , Tan Choon‐Hong 
Published: March 2012

AbstractThe approach avoids the use of metal catalysts and stoichiometric amounts of peroxy compounds as terminal oxidant.
ChemInform Abstract: Broensted Acid Assisted Activation of Imide Carbonyl Group: Regioselective Synthesis of Isoindoloisoquinolinone Alkaloid (.+‐.)‐Nuevamine.
Authors: Selvakumar Jayaraman , Ramanathan Chinnasamy Ramaraj 
Published: March 2012

AbstractThe intramolecular cyclization of phenethylphthalimides (I) and (IV) gives a fused isoindoloisoquinolinone skeleton.
ChemInform Abstract: Silver‐Catalyzed Intramolecular Cyclization of 2‐Alkynylacetophenones and 3‐Acetyl‐2‐alkynylpyridines in the Presence of Ammonia.
Authors: Dell'Acqua Monica , Abbiati Giorgio , Arcadi Antonio , Rossi Elisabetta 
Published: March 2012

AbstractSilver triflate is the catalyst of choice for the microwave‐promoted domino nucleophilic addition/annulation reaction of a variety of 2‐alkynyl‐acetophenones (I) and acetyl‐2‐alkynylpyridines (IV) in the presence of ammonia.
ChemInform Abstract: Synthesis of New Fluorine‐Containing Pyrazolo[3,4‐b]pyridinones as Promising Drug Precursors.
Authors: Golubev A. S. , Starostin G. S. , Chunikhin K. S. , Peregudov A. S. , Rodygin K. C. , Rubtsova S. A. , Slepukhin P. A. , Kuchin A. V. , Chkanikov N. D. 
Published: March 2012

AbstractThe approaches to the synthesis of earlier unknown title compounds containing the 4‐ArSCF2 and 4‐ArSCHF groups involve i) direct annulation of substituted aminopyrazoles (I) with halogenated acetoacetates like (II), (V), and (X), and ii) replacement of the Br atom of the 4‐CF2Br group, or the Cl atom of the 4‐CHFCl group by sodium arenethiolates (VII) and (XII).
ChemInform Abstract: One‐Pot Synthesis of 1,3,6,8‐Tetraazapyrenes.
Authors: Aksenov A. V. , Lyakhovnenko A. S. , Perlova T. S. , Aksenova I. V. 
Published: March 2012

AbstractThe use of formic acid for the ring closure allows the synthesis of unsubstituted 1,3,6,8‐tetraazapyrene (IIIa).
ChemInform Abstract: Mono‐ and Bis‐Pyrimido[1,2‐a]benzimidazoles: Alum‐Catalyzed Regioselective Three‐ or Pseudo Five‐Component Reaction of 2‐Aminobenzimidazole with Aldehyde and Malononitrile.
Authors: Karimi Ali R. , Bayat Fahimeh 
Published: March 2012

AbstractThe efficient and regioselective one‐pot synthesis of the compounds (IV) and (VI) uses an inexpensive, water‐soluble, non‐toxic, and commercially available catalyst.
ChemInform Abstract: Efficient Synthesis of 7‐Benzyl‐5,6,7,8‐tetrahydropyrido[4′,3′:4,5]thieno [2,3‐d]pyrimidin‐4(3H)‐ones via Aza‐Wittig Reaction.
Authors: Chen Hong , Yan Kai , Liu Ming‐Guo 
Published: March 2012

AbstractA facile and efficient one‐pot route for the synthesis of the title compounds (IV), (VI), and (VIII) is presented.
ChemInform Abstract: Synthesis of 1H‐1,5,7‐Triazacyclopenta[c,d]phenalenes Involving Electrophilic Amination of 1H‐Perimidines with Sodium Azide in Polyphosphoric Acid.
Authors: Aksenov A. V. , Lyakhovnenko A. S. , Andrienko A. V. 
Published: March 2012

AbstractThe peri‐annulation of the pyrrole ring to perimidines is based on the reagent combination sodium azide/polyphosphoric acid and affords the hitherto unknown title compounds (III) in a one‐pot fashion.
ChemInform Abstract: An Efficient Copper‐Catalyzed Microwave‐Assisted S‐Arylation Towards the Synthesis of 8‐Arylsulfanyl Adenines.
Authors: Sun Weilin , Patel Pallav D. , Stephani Ralph A. , Chiosis Gabriela 
Published: March 2012

AbstractOptimized conditions are developed for the different types of substrates to prepare the pharmaceutically important title compounds in moderate to good yields.
ChemInform Abstract: One‐Pot Synthesis of Pyrrolo[1,2‐a]quinoxalines.
Authors: Huang Aiping , Liu Feng , Zhan Chunjing , Liu Yanli , Ma Chen 
Published: March 2012

AbstractTitle compounds (III), (VI) and its analogues (VIII), (X), and (XII) are synthesized via the transition metal free regioselective condensation of 1,2‐dihalobenzenes or 2‐halonitroarenes (I), (IV) (VII), and (IX) with pyrrole‐2‐carboxamides derivatives (II), (V), and (XI).
ChemInform Abstract: Practical Method for Parallel Synthesis of Diversely Substituted 1‐Phenylpiperazines.
Authors: Konstantinov Igor , Bukhryakov Konstantin , Gezentsvey Yuri , Krasavin Mikhail 
Published: March 2012

AbstractThe simple and practical method used for the synthesis of title compounds (III) fails for anilines containing a basic motif like 4‐aminopyridine and for unreactive heteroaromatic amines.
ChemInform Abstract: Reactions of 6,7‐Dimethoxy‐3,4‐dihydroisoquinoline with o‐Quinone Methides.
Authors: Osyanin V. A. , Ivleva E. A. , Osipov D. V. , Klimochkin Yu. N. 
Published: March 2012

AbstractWhereas o‐hydroxybenzyl alcohols (I) give N‐alkylation products with title reagent (II), Mannich bases (IV) react in a [4+2] cycloaddition.
ChemInform Abstract: Novel Synthesis of Oxonine Derivatives from 3‐[(2‐Aminophenyl)amino]‐5,5‐dimethyl‐2‐cyclohexene‐1‐one and o‐Quinones.
Authors: Ukhin Lev Yu. , Suponitsky Kyrill Yu. , Shepelenko Eugenii N. , Belousova Lyudmila V. , Borodkin Gennadii S. 
Published: March 2012

AbstractThe reaction of unsymmetrical o‐quinones (I) and (V) with title compound (II) in the presence of TFA gives novel 9‐membered lactones (III) and (VI), respectively.
ChemInform Abstract: Reactions of 2‐Hydroxymethylphenols with Lawesson′s Reagent.
Authors: Osyanin V. A. , Ivleva E. A. , Klimochkin Yu. N. 
Published: March 2012

AbstractThe reaction mechanism probably includes the thermal generation of an o‐quinone methide and subsequent 1,4‐addition of a Lawesson reagent monomer.
ChemInform Abstract: Titanocene Dichloride as an Efficient Catalyst for One‐Pot Synthesis of α‐Aminophosphonates.
Authors: Niu Hong‐Ying , Li Hui‐Juan , Li Jian‐Ping , Huang Yu , Mao Run‐Ze , Li De‐Yang , Qu Gui‐Rong , Guo Hai‐Ming 
Published: March 2012

AbstractA chemoselective, green, rapid, and convenient method for the synthesis of title compounds (IV), (VI), and (VIII) uses a safe, inexpensive, and commercially available catalyst.
ChemInform Abstract: Synthesis and Alkylation of Triethylammonium 3,5,5‐Tricyano‐4,6‐di (2‐thienyl)‐1,4,5,6‐tetrahydropyridine‐2‐selenolate.
Authors: Frolov K. A. , Krivokolysko S. G. 
Published: March 2012

AbstractThe synthesis of the new selenium‐substituted tetrahydropyridine (IV) and its alkylation are described.
ChemInform Abstract: A Rearrangement in the Reaction of 2‐Bromomethyl‐1,3‐thiaselenole with Ethanol: Synthesis of 2‐Ethoxy‐2,3‐dihydro‐1,4‐thiaselenine.
Authors: Amosova S. V. , Penzik M. V. , Potapov V. A. , Albanov A. I. 
Published: March 2012

AbstractThiaselenole derivative (I) rearranges by nucleophilic substitution and subsequent ring expansion to furnish the hitherto unknown dihydrothiaselenine (III), obtained together with polymerization products.
ChemInform Abstract: Novel Semisquaraine Regioisomers: Isolation, Divergent Chemical Reactivity and Photophysical Properties.
Authors: Avirah Rekha R. , Jyothish Kuthanapillil , Suresh Cherumuttathu H. , Suresh Eringathodi , Ramaiah Danaboyina 
Published: March 2012

AbstractThe reaction of quinaldinium iodides (I) with squaric acid (II) and butanol leads to zwitterionic semisquaraines (IV) in high yields, whilst similar reaction of salts (I) with 1,4‐dibutyl squarate (V) gives rise to neutral isomers (VI).
ChemInform Abstract: Synthesis of Hybrid Photochromes Containing Fulgimide and Salicylidenaniline Fragments and Study of Their Properties.
Authors: Luyksaar S. I. , Platonova I. V. , Krayushkin M. M. , Barachevskii V. A. , Molchanov S. P. 
Published: March 2012

AbstractVarious fulgimides (I) are synthesized which exhibit photochromic properties in solution and also in solid‐phase films.
ChemInform Abstract: Salacetal, and Oleanane‐Type Triterpene from Salacia longipes var. camerunensis.
Authors: Mba'ning Brice M. , Lenta Bruno N. , Ngouela Silvere , Noungoue Diderot T. , Tantangmo Ferdinand , Talontsi Ferdinand M. , Tsamo Etienne , Laatsch Hartmut 
Published: March 2012

AbstractAll isolated compounds including salacetal (I) are tested for their antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli, as well as their anti fungal potency against Candida albicans and Mucor miehei.
ChemInform Abstract: Transesterification of α‐Amino Esters Catalyzed by a Tetranuclear Zinc Cluster: Zn4(OCOCF3)6O.
Authors: Maegawa Yusuke , Agura Kazushi , Hayashi Yukiko , Ohshima Takashi , Mashima Kazushi 
Published: March 2012

AbstractIt is demonstrated that the zinc cluster efficiently promotes the transesterification of N‐protected α‐amino acid methyl esters with a variety of alcohols.
ChemInform Abstract: Synthesis of Novel 1,3,4‐Oxadiazole Derivatives and Their Nucleoside Analogues with Antioxidant and Antitumor Activities.
Authors: Fadda A. A. , Abdel‐Rahman A. A.‐H. , El‐Sayed W. A. , Zidan T. A. , Badria F. A. 
Published: March 2012

AbstractThe title compound (VI) shows the highest antioxidant activity and (III) exhibits strong cytotoxicity.
ChemInform Abstract: Atacamycins A—C, 22‐Membered Antitumor Macrolactones Produced by Streptomyces sp. C38.
Authors: Fiedler Hans‐Peter , et al. et al. 
Published: March 2012

AbstractTitle compounds (I) are found to exhibit moderate inhibitory effects against phosphodiesterase (PDE‐4B2).
ChemInform Abstract: Natural Products‐Based Insecticidal Agents. Part 8. Design, Semisynthesis and Insecticidal Activity of Novel O‐(Deoxypodophyllotoxin‐4′‐yl)‐(N‐((un)substituted benzyl)indol‐3‐yl)glyoxylesters Against Mythimna separata Walker.
Authors: Wang Yi , Xu Hui 
Published: March 2012

AbstractTitle compounds (I) are synthesized starting from indoles and benzyl chlorides.
ChemInform Abstract: Total Synthesis and Absolute Configuration of Avenolide, Extracellular Factor in Streptomyces avermitilis.
Authors: Uchida Miho , Takamatsu Satoshi , Arima Shiho , Miyamoto Kiyoko T. , Kitani Shigeru , Nihira Takuya , Ikeda Haruo , Nagamitsu Tohru 
Published: March 2012

Abstract(4S,10R)‐Avenolide (I), its (4S,10S)‐isomer and 10‐deoxy avenolide are synthesized.
ChemInform Abstract: Nanoarchitectonics for Mesoporous Materials
Authors: Ariga Katsuhiko , Vinu Ajayan , Yamauchi Yusuke , Ji Qingmin , Hill Jonathan P. 
Published: March 2012

AbstractReview: e.g. semiconductive materials, organic composites, carbon nitride, boron nitride, mesoporous silica etc.; 551 refs.
ChemInform Abstract: 1,2‐Benzoquinones in Diels—Alder Reactions, Dipolar Cycloadditions, Nucleophilic Additions, Multicomponent Reactions and More
Authors: Nair Vijay , Menon Rajeev S. , Biju Akkattu T. , Abhilash K. G. 
Published: March 2012

AbstractReview: 62 refs.
A new solution algorithm for solving rule‐sets based bilevel decision problems
Authors: Lu Jie , Zheng Zheng , Zhang Guangquan , He Qing , Shi Zhongzhi 
Published: March 2012

SummaryBilevel decision addresses compromises between two interacting decision entities within a given hierarchical complex system under distributed environments. Bilevel programming typically solves bilevel decision problems. However, formulation of objectives and constraints in mathematical functions is required, which are difficult, and sometimes impossible, in real‐world situations because of various uncertainties. Our study develops a rule‐set based bilevel decision approach, which models a bilevel decision problem by creating, transforming and reducing related rule sets. This study develops a new rule‐sets based solution algorithm to obtain an optimal solution from the bilevel decision problem described by rule sets. A case study and a set of experiments illustrate both functions and the effectiveness of the developed algorithm in solving a bilevel decision problem. Copyright © 2012 John Wiley & Sons, Ltd.
Parallelizing a Black‐Scholes solver based on finite elements and sparse grids
Authors: Bungartz H.‐J. , Heinecke A. , Pflüger D. , Schraufstetter S. 
Published: March 2012

SUMMARYWe present the parallelization of a sparse grid finite element discretization of the Black–Scholes equation, which is commonly used for option pricing. Sparse grids allow to handle higher dimensional options than classical approaches on full grids and can be extended to a fully adaptive discretization method. We introduce the algorithmical structure of efficient algorithms operating on sparse grids and demonstrate how they can be used to derive an efficient parallelization with OpenMP of the Black–Scholes solver. We show results on different commodity hardware systems based on multi‐core architectures with up to 24 cores and discuss the parallel performance using Intel and Advanced Micro Devices (AMD) CPUs. Copyright © 2012 John Wiley & Sons, Ltd.
A Special Conjugated Model around sp3 Carbon Atoms: Density Functional Theory Study on the Homoaromatic Electron Delocalization and Applications of Benzo‐Fused Tetra(triptycene)porphyrins
Authors: Qi Dongdong , Zhang Lijuan , Zhao Luyang , Cai Xue , Jiang Jianzhuang 
Published: March 2012

AbstractThe three‐unit homoaromatic electron‐delocalizing nature of the benzo‐fused tetra(triptycene)porphyrins (TTPs) with a three‐dimensional conjugated model is clarified using density functional theory studies. Due to the electron delocalization, the unidirectional photon‐induced current of this kind of TTP molecular skeleton with a highest efficiency of about 90 % in the range between 350 and 500 nm gives them great potential as efficient solar antenna collectors. In addition, their active triptycene cups fused at the central porphyrin core render possible potential application in host–guest chemistry.
The evolution of dispersal conditioned on migration status
Authors: Asaduzzaman Sarder Mohammed , Wild Geoff 
Published: March 2012

AbstractWe consider a model for the evolution of dispersal of offspring. Dispersal is treated as a parental trait that is expressed conditional upon a parent’s own “migration status,” that is, whether a parent, itself, is native or nonnative to the area in which it breeds. We compare the evolution of this kind of conditional dispersal to the evolution of unconditional dispersal, in order to determine the extent to which the former changes predictions about population‐wide levels of dispersal. We use numerical simulations of an inclusive‐fitness model, and individual‐based simulations to predict population‐average dispersal rates for the case in which dispersal based on migration status occurs. When our model predictions are compared to predictions that neglect conditional dispersal, observed differences between rates are only slight, and never exceed 0.06. While the effect of dispersal conditioned upon migration status could be detected in a carefully designed experiment, we argue that less‐than‐ideal experimental conditions, and factors such as dispersal conditioned on sex are likely to play a larger role that the type of conditional dispersal studied here.
Causal uncertainty during initial interactions
Authors: Boucher Eliane M. , Jacobson Jill A. 
Published: March 2012

AbstractCausal uncertainty (CU) refers to persistent doubts people have about their ability to understand causes of social events. Although such confusion about social dynamics should affect social exchanges, previous research has been limited to the realm of social cognition (i.e., computer‐based studies exploring perceptions of hypothetical others). In three studies, we explored CU effects during real‐time social interactions with unacquainted conversational partners. We found that high CU participants perceived their conversations and conversational partners more negatively than did low CU participants and that these negative social perceptions stemmed from an inability to sufficiently reduce their cognitive uncertainty. Copyright © 2012 John Wiley & Sons, Ltd.
Numerical modelling of carbon fibre‐reinforced polymer and hybrid reinforced concrete beams in fire
Authors: Rafi Muhammad Masood , Nadjai Ali 
Published: March 2012

ABSTRACTInvestigation on the fire resistance of fibre‐reinforced polymer (FRP) reinforced concrete (RC) is essential for increased application of FRP bars in the construction industry. Experimental tests for determining the fire resistance of RC elements tend to be expensive and time‐consuming. Although numerical models provide an effective alternative to these tests, their use in case of FRP RC structures is hindered because of the insufficient constitutive laws for FRP bars at elevated temperatures. This paper presents the details of a numerical modelling work that was carried out for simply supported carbon FRP (CFRP) and hybrid (steel‐FRP) bar RC beams at elevated temperatures. Constitutive laws for determining temperature‐dependent strength and stiffness properties of CFRP bars are proposed. Numerical models based on finite element modelling were employed for the rational analysis of beams using the proposed constitutive laws. The behaviour of concrete was simulated by means of a smeared crack model based on the tangent stiffness solution algorithm. The employed numerical models were validated against previous experimental results. The theoretical rebar stresses were calculated in both the FRP and steel bars, and the differences are discussed. Copyright © 2012 John Wiley & Sons, Ltd.
Two‐Phase Stratified Sampling Designs for Regional Sequencing
Authors: Chen Zhijian , Craiu Radu V. , Bull Shelley B. 
Published: March 2012

AbstractBy systematic examination of common tag single‐nucleotide polymorphisms (SNPs) across the genome, the genome‐wide association study (GWAS) has proven to be a successful approach to identify genetic variants that are associated with complex diseases and traits. Although the per base pair cost of sequencing has dropped dramatically with the advent of the next‐generation technologies, it may still only be feasible to obtain DNA sequence data for a portion of available study subjects due to financial constraints. Two‐phase sampling designs have been used frequently in large‐scale surveys and epidemiological studies where certain variables are too costly to be measured on all subjects. We consider two‐phase stratified sampling designs for genetic association, in which tag SNPs for candidate genes or regions are genotyped on all subjects in phase 1, and a proportion of subjects are selected into phase 2 based on genotypes at one or more tag SNPs. Deep sequencing in the region is then applied to genotype phase 2 subjects at sequence SNPs. We investigate alternative sampling designs for selection of phase 2 subjects within strata defined by tag SNP genotypes and develop methods of inference for sequence SNP variant associations using data from both phases. In comparison to methods that use data from phase 2 alone, the combined analysis improves efficiency. Genet. Epidemiol. 36:312–319, 2012. © 2012 Wiley Periodicals, Inc.