bluuebunny/crossref_metadata_2025_split huggingface dataset:
The causal role of multiple psycho-emotional disorders in gastroesophageal reflux disease: A two-sample Mendelian randomized study
Authors: Wang Jing , Song Meng , Cao Mingbo 
Published: May 2024

Background
Observational studies have previously shown a potential link between psycho-emotional disorders, such as mood swings, highly strung, anxious feelings, and gastroesophageal reflux disease (GERD). However, the credibility of these associations could be influenced by various confounding factors. Consequently, our study sought to employ a Mendelian randomization (MR) approach to elucidate a potential causal relationship between psycho-emotional disorders and GERD.

Method
Information on independent genetic variants linked to mood swings, highly strung, and anxious feelings was gathered from European populations participating in the IEU Open GWAS research. The FinnGen Consortium provided the genome-wide association study (GWAS) summary statistics for GERD. Our analysis employed the inverse variance weighted (IVW) method under the random effects model as the main analytical method. To further bolster our findings, we employed the weighted median and MR Egger methods. In addition, we conducted a series of sensitivity analyses.

Results
Our study supports the existence of a causal relationship between psycho-emotional disorders and GERD. Mood swings, highly strung, and anxious feelings adversely affected GERD risk (mood swings: OR 2.21, 95% CI 1.19–5.59, p = 3.09 × 10–2; highly strung: OR 5.63, 95% CI 1.77–17.94, p = 3.42 × 10–3; anxious feelings: OR 2.48, 95% CI 1.08–4.33, p = 2.89 × 10–2).

Conclusion
This Mendelian randomization study provides robust support for the notion that mood swings, highly strung and anxious feelings, are associated with an increased risk of developing GERD.
Impact of depression on self-efficacy, illness perceptions and self-management among people with type 2 diabetes: A systematic review of longitudinal studies
Authors: Derese Andualem , Gebreegzhiabhere Yohannes , Medhin Girmay , Sirgu Sisay , Hanlon Charlotte 
Published: May 2024

Background
Treating comorbid depression does not always improve outcomes for people with type 2 diabetes. Evidence is lacking on potential psychological and behavioural intermediaries of the impact of depression on diabetes outcomes.

Objective
To synthesise evidence on the impact of comorbid depression on self-efficacy, illness perceptions, and self-management in people with type 2 diabetes.

Data sources
We searched PubMed, Embase, PsycINFO, and Global Health databases from inception up to 29th March 2023.

Study eligibility criteria
Only prospective studies (cohort or intervention studies) were included, with no restrictions on language. The outcomes were self-efficacy, illness perceptions, and self-management.

Participants
People with type 2 diabetes in community or health settings.

Exposure
Comorbid depression or depressive symptoms in people with type 2 diabetes.

Synthesis of results
A narrative review of heterogeneous studies.

Risk of bias
The risk of bias was assessed using the Effective Public Health Practice Project (EPHPP) quality assessment tool for quantitative studies.

Results
Twenty-five studies were included, all from high-income countries. Depression was associated with lower self-efficacy (2 studies), poor illness perception (1 study), and poor self-management practices (17 studies) in people with type 2 diabetes. In 6/7 studies, depressive symptoms predicted less adherence to dietary recommendations, 8/10 studies found depressive symptoms were associated with poor medication adherence, 1/3 study found that depressive symptoms were associated with poor weight control, 3/4 with less physical exercise, and 2/3 with general self-care practices.

Limitations
There were no studies from low- and middle-income countries and non-Western settings, and we cannot assume the mechanisms linking comorbid depression with diabetes outcomes are similar.

Conclusions
Comorbid depression was associated with lower self-efficacy, poorer self-management, and less adaptive illness perceptions among people with diabetes.
Introduction of robotic pancreatoduodenectomy following phase 2a IDEAL guidelines
Authors: Mise Yoshihiro , Miyashita Mamiko , Yoshioka Ryuji , Kawano Fumihiro , Takeda Yoshinori , Ichida Hirofumi , Saiura Akio 
Published: May 2024

Background
Robotic pancreatoduodenectomy (RPD) is a newly introduced procedure, which is still evolving and lacks standardization. An objective assessment is essential to investigate the feasibility of RPD. The current study aimed to assess our initial ten cases of RPD based on IDEAL (Idea, Development, Exploration, Assessment, and Long-term study) guidelines.

Methods
This was a prospective phase 2a study following the IDEAL framework. Ten consecutive cases of RPD performed by two surgeons with expertise in open procedures at a single center were assigned to the study. With objective evaluation, each case was classified into four grades according to the achievements of the procedures. Errors observed in the previous case were used to inform the procedure in the next case. The surgical outcomes of the ten cases were reviewed.

Results
The median total operation time was 634 min (interquartile range [IQR], 594–668) with a median resection time of 363 min (IQR, 323–428) and reconstruction time of 123 min (IQR, 107–131). The achievement of the whole procedure was graded as A, “successful”, in two patients. In two patients, reconstruction was performed with a mini-laparotomy due to extensive pneumoperitoneum, probably caused by insertion of a liver retractor from the xyphoid. Major postoperative complications occurred in two patients. One patient, in whom the jejunal limb was elevated through the Treitz ligament, had a bowel obstruction and needed to undergo re-laparotomy.

Conclusions
RPD is feasible when performed by surgeons experienced in open procedures. Specific considerations are needed to safely introduce RPD.
Elemen Desain yang Adaptif terhadap Kebijakan Adaptasi Kebiasaan Baru Pandemi COVID-19 di Kawasan Alun-Alun Klaten
Authors: Santoso Ersan Putro , Suwandono Djoko 
Published: May 2024

Pandemi COVID-19 merupakan bencana skala global sejak tahun 2020 yang melahirkan perilaku baru bagi masyarakat dengan mengharuskan adanya protokol kesehatan : menjaga jarak, memakai masker, dan rajin mencuci tangan. Ruang publik merupakan ruang yang masih dikunjungi oleh banyak orang di masa pandemi, salah satunya Alun-Alun Klaten. Banyak ruang publik didesain dengan prinsip close (dekat) dan closure (tertutup). Prinsip tersebut saat pandemi ternyata bertentangan dengan kebijakan protokol kesehatan sehingga diperlukan penyesuaian. Oleh karena itu, penelitian ini dilakukan dengan tujuan untuk mengidentifikasi penerapan elemen desain di Kawasan Alun-Alun Klaten yang adaptif terhadap Kebijakan Adaptasi Kebiasaan Baru Pandemi COVID-19. Penelitian ini menggunakan metode kuantitatif dengan teknik analisis statistik deskriptif dan skoring. Pengumpulan data dilakukan dengan observasi lapangan dan studi dokumen. Teknik sampling yang digunakan adalah berupa accidental sampling dengan ukuran sampel sejumlah 865 sampel. Penelitian ini dilakukan dengan menganalisis aktivitas pengguna dan kesesuaian elemen desain terhadap protokol kesehatan. Hasil penelitian menunjukkan bahwa elemen desain di Alun-Alun Klaten berupa bangku taman, jalur pedestrian, bangunan pedagang kaki lima, dan tempat cuci tangan belum mampu mewadahi aktivitas pengguna di tengah kondisi Pandemi COVID-19. Oleh karena itu, Alun-Alun Klaten perlu menerapkan flexible design terhadap elemen desain yang sudah ada dengan melakukan penyesuaian desain sesuai prinsip protokol kesehatan. Kata kunci: Aktivitas pengguna; Elemen desain; Protokol kesehatan.
Oblicza rosyjskiego tradycjonalizmu kulturowego (rozważania w cieniu ‘zetyzmu’)
Authors: Jedliński Marek 
Published: May 2024

Цель статьи – представить различные образы русского культурного традиционализма в контексте идеологии зетизма (связанной с агрессией России против Украины). В первой части статьи рассматриваются теоретические положения традиции и традиционализма. Во второй части представлена ​​концепция археомодернизма Александра Дугина, взгляды Николая Бердяева на демократию, создание большевиками собственной традиции (время, календарь) и русский, традиционалистский взгляд на проблемы телесности, интимности, женственности и сексуальности. Во всех случаях можно увидеть глубоко укоренившийся русский культурный традиционализм.
The effects of myosteatosis on skeletal muscle function in older adults
Authors: Dondero Kathleen , Friedman Ben , Rekant Julie , Landers‐Ramos Rian , Addison Odessa 
Published: May 2024

AbstractMyosteatosis, or the infiltration of fatty deposits into skeletal muscle, occurs with advancing age and contributes to the health and functional decline of older adults. Myosteatosis and its inflammatory milieu play a larger role in adipose tissue dysfunction, muscle tissue dysfunction, and increased passive muscle stiffness. Combined with the age‐related decline of sex hormones and development of anabolic resistance, myosteatosis also contributes to insulin resistance, impaired muscle mechanics, loss of force production from the muscle, and increased risk of chronic disease. Due to its highly inflammatory secretome and the downstream negative effects on muscle metabolism and mechanics, myosteatosis has become an area of interest for aging researchers and clinicians. Thus far, myosteatosis treatments have had limited success, as many lack the potency to completely rescue the metabolic and physical consequences of myosteatosis. Future research is encouraged for the development of reliable assessment methods for myosteatosis, as well as the continued exploration of pharmacological, nutritional, and exercise‐related interventions that may lead to the success in attenuating myosteatosis and its clinical consequences within the aging population.
Thyroglobulin measurement is the most powerful outcome predictor in differentiated thyroid cancer: a decision tree analysis in a European multicenter series
Authors: Giovanella Luca , Milan Lisa , Roll Wolfgang , Weber Manuel , Schenke Simone , Kreissl Michael , Vrachimis Alexis , Pabst Kim , Murat Tuncel , Petranović Ovčariček Petra , Campenni Alfredo , Görges Rainer , Ceriani Luca 
Published: May 2024

Abstract

Objectives
An accurate prognostic assessment is pivotal to adequately inform and individualize follow-up and management of patients with differentiated thyroid cancer (DTC). We aimed to develop a predictive model for recurrent disease in DTC patients treated by surgery and 131I by adopting a decision tree model.

Methods
Age, sex, histology, T stage, N stage, risk classes, remnant estimation, thyroid-stimulating hormone (TSH), thyroglobulin (Tg), administered 131I activities and post-therapy whole body scintigraphy (PT-WBS) were identified as potential predictors and put into regression algorithm (conditional inference tree, c-tree) to develop a risk stratification model for predicting persistent/recurrent disease over time.

Results
The PT-WBS pattern identified a partition of the population into two subgroups (PT-WBS positive or negative for distant metastases). Patients with distant metastases exhibited lower disease-free survival (either structural, DFS-SD, and biochemical, DFS-BD, disease) compared to those without metastases. Meanwhile, the latter were further stratified into three risk subgroups based on their Tg values. Notably, Tg values >63.1 ng/mL predicted a shorter survival time, with increased DFS-SD for Tg values <63.1 and <8.9 ng/mL, respectively. A comparable model was generated for biochemical disease (BD), albeit different DFS were predicted by slightly different Tg cutoff values (41.2 and 8.8 ng/mL) compared to DFS-SD.

Conclusions
We developed a simple, accurate and reproducible decision tree model able to provide reliable information on the probability of structurally and/or biochemically persistent/relapsed DTC after a TTA. In turn, the provided information is highly relevant to refine the initial risk stratification, identify patients at higher risk of reduced structural and biochemical DFS, and modulate additional therapies and the relative follow-up.
The distribution of Manin’s iterated integrals of modular forms
Authors: Matthes Nils , Risager Morten S. 
Published: May 2024

AbstractWe determine the asymptotic distribution of Manin’s iterated integrals of length at most 2. For all lengths, we compute all the asymptotic moments. We show that if the length is at least 3, these moments do in generalnotdetermine a unique distribution.
Numerical investigation of smart material-based structures for vibration energy-harvesting applications
Authors: Atul  , Deepak G. Divya 
Published: May 2024

Abstract
The present work deals with energy-harvesting devices, which are useful in scavenging power using piezoelectric materials. Utilizing classical beam theory and classical plate theory, finite element modelling has been carried out to optimize the performance of output power of a cantilever beam and a flexible rectangular plate. Harmonic oscillations and base excitation will be the two different forcing functions used to drive the system. Based on this, numerical investigations of the performance of output power for the piezoelectric cantilever beam and flexible rectangular plate with different cases are considered. The present work is also useful for designing the piezoelectric cantilever beams and plates to extract maximum output power within the frequency ranges from 0 to 200 Hz. Numerical investigations on the piezoelectric cantilever beam and flexible rectangular plate with different cases reveal that the performance of output power is influenced by factors like load resistance, applications of with and without host structures, and different design parameters like unimorph, bimorph, embedded, line- and cross-type piezoelectric patch arrangements.
Hydrothermal enzyme pretreatment on structure and properties of apple branches
Authors: Yuan Jieying , Li Yibo , Li Shulei , Liu Zheyun , Lu Yunjing , Dang Shuoyu , Ding Fan , Yu Ruijin , Chu Jie 
Published: May 2024

Abstract
Pretreatment serves as an important step in maximizing the efficient utilization of woody biomass feedstock. This study focused on enhancing the component and structural properties of apple wood to optimize the utilization of apple wood resources effectively. This study presents the optimization of, the apple wood pretreatment system, combining bioenzyme and hydrothermal treatments. This study aimed to investigate the effect of different bioenzyme pretreatment conditions on the components and structural properties of apple wood extract and to analyze the feasibility of enzyme solution reuse. Fourier transform infrared spectroscopy analysis revealed an increase in cellulose content in the wood flour following enzyme treatment. Concurrently, changes in characteristic peaks indicated an increased hemicellulose content and a reduction in lignin content after the pretreatment, correlating with fraction analysis results. Scanning electron microscopy illustrated that the dense structure of the fiber surface was disrupted after treatment. Notably, the results indicated that the recovered biocomposite enzymes exhibited excellent activity, suggesting their potential for reuse.
Physicochemical properties, the digestible and resistant starch content of chestnut flour with different particle sizes
Authors: EREM Fundagül 
Published: May 2024

AbstractIn this study, chestnuts were processed into flour, and the obtained chestnut flour (CF) was passed through a sieve with an aperture size of 212 µm. Then the physicochemical properties, digestible and resistant starch contents of CF1 (<212 µm), CF2 (≥212 µm), and commercial chestnut flour (CCF) were determined. It was found that CCF had the highest values in terms of proximate composition, total soluble polyphenol content (891.25 mg GAE/100 g), and antioxidant activity (ABTS: 1552.11 mg TE/100 g, DPPH: 2003.01 mg TE/100 g). On the other hand, CF1 was superior in terms of resistant starch content (39.31 g/100 g, dw) (p < 0.05). The resistant starch content of CF1 was approximately 1.5-fold and 3-fold higher than CCF and CF2, respectively. Furthermore, the rapidly digestible starch content of CF1 (2.1 g/100 g, dw) and CF2 (0.93 g/100 g, dw) was quite lower than CCF (12.64 g/100 g, dw) (p < 0.05). Moreover, CF1 exhibited lower (p < 0.05) water, alkaline water, and sodium carbonate retention capacities, which make it a potential good flour for cookie and cracker production. In contrast, CF2 could be evaluated as a good ingredient for noodle-type foods due to its lower water solubility index. Considering the least gelation concentrations of samples, it was seen that CF1 (% 10) could also be valorized as a thickening or gelation agent in the food industry, as well as CCF (% 6).
“Let’s talk divorce”: a multimodal critical discourse analysis of Oduduwa secessionist discourse
Authors: Aminu PraiseGod , Awopetu Ifeoluwa , Unuabonah Foluke Olayinka 
Published: May 2024

Abstract
This study explores ideological representations in the online images of the Oduduwa secessionist movement in Nigeria from a multimodal critical discourse analytical framework. The data, which comprise selected internet images obtained from the Facebook and Twitter accounts of the group, were qualitatively analyzed. The findings reveal that the images are ideologically designed to resist the Nigerian nation, call for the Yoruba nation, signal membership polarization, construct an Oduduwa national identity, construct the betrayal of the Yoruba nation, accentuate violence in Nigeria, and delegitimize the Nigerian nation. We argue that these discursive strategies are used to project resistance as well as radical and secessionist ideologies, which appear to be typical of secessionist organizations around the world. Additionally, this article sheds light on the paramount significance of ethnic identity in the organizational dynamics of resistance groups operating within the Nigerian context.
Healthcare workers’ attitudes toward children getting Covid-19 vaccinations in Gaza Strip
Authors: Sha Shuying , Abusalem Said Kamel , Abuhammad Sawsan , Al-Jeesh Yousef 
Published: May 2024

Abstract

Background and objectives
Healthcare workers’ (HCWs) attitudes toward vaccine greatly influences individuals’ vaccine acceptance rate. Research in high-income countries identified five key person-level factors for vaccine hesitancy. Perception of vaccine were different in low-income or developing country, and the reason for vaccine hesitancy might not be the same as that in developed countries. This study assesses HCWs parents’ attitude toward their child getting COVID-19 vaccine and the potential influencing factors in HCWs living in Gaza Strip.

Method
This is a secondary data analysis of a cross-sectional survey collected from 245 HCWs in Gaza between February and May in 2021. Multinominal logistic regression was used to model the association between vaccine hesitancy and potential influencing factors.

Results
Only 27.2% HCWs parents in Gaza responded that they would like their children to get vaccinated. Higher perceived benefits of vaccine and having flu shot in last year were significantly related to higher vaccine intention (P-values <0.001). However, perceived susceptibility, perceived vaccine safety, and vaccine effectiveness were not significantly associated with vaccine hesitancy.

Conclusion
Intervention in Gaza Strip should focus on educating people on vaccine benefits to foster the acceptance of the vaccine.
Tramadol-paracetamol for postoperative pain after spine surgery – A randomized, double-blind, placebo-controlled study
Authors: Lappalainen Emma , Huttunen Jukka , Kokki Hannu , Toroi Petri , Kokki Merja 
Published: May 2024

Abstract

Objectives
Multimodal pain management is one component in enhanced recovery after surgery protocol. Here we evaluate the efficacy of tramadol–paracetamol in acute postoperative pain and pain outcome at 12 months after spine surgery in randomized, double-blind, placebo-controlled trial.

Methods
We randomized 120 patients undergoing spine surgery to receive, for add-on pain management, two tramadol–paracetamol 37.5 mg/325 mg (n = 61) or placebo tablets (n = 59) twice a day for 5 postoperative days. In the hospital, multimodal pain management consisted of dexketoprofen and oxycodone. After discharge, patients were prescribed ibuprofen 200 mg, maximum 1,200 mg/day. Pain, analgesic use, and satisfaction with pain medication were followed up with the Brief Pain Inventory questionnaire before surgery and at 1 and 52 weeks after surgery. The primary outcome was patients’ satisfaction with pain medication 1 week after surgery.

Results
At 1 week after surgery, patients’ satisfaction with pain medication was similarly high in the two groups, 75% [interquartile range, 30%] in the placebo group and 70% [40%] in the tramadol–paracetamol group (p = 0.949) on a scale: 0% =  not satisfied, 100% = totally satisfied. At 1 week, ibuprofen dose was lower in the placebo group 200 mg [1,000] compared to the tramadol–paracetamol group, 800 mg [1,600] (p = 0.016). There was no difference in the need for rescue oxycodone. Patients in the tramadol–paracetamol group had more adverse events associated with analgesics during the first postoperative week (relative risk = 1.8, 95% confidence interval, 1.2–2.6).

Conclusion
Add-on pain treatment with tramadol–paracetamol did not enhance patients’ satisfaction with early pain management after back surgery.
Surface mortar detection and performance evaluation of recycled aggregates based on hyperspectral technology
Authors: Liu Wenqian , Fang Huaiying , Yang Jianhong , Tan Guoyi 
Published: May 2024

Abstract
The quality of recycled aggregates is affected by the residual mortar. It is significant to detect the surface mortar distribution of recycled aggregates after mortar removal by mechanical crushing. From this perspective, a method to accurately detect the surface mortar distribution of recycled aggregates is proposed. The processed hyperspectral features were obtained by applying data filtering and screening, L2 norm processing, feature transforming and dimensionality reduction. Then these features were put into an extreme learning machine (ELM) for offline training, and a sliding window processing mechanism was added to the trained model, which was used to detect the recycled aggregates and output the category images. Finally, two characterization parameters of the proportion of mortar area and the mortar volume were extracted from the images. The regression models of water absorption (WA) and apparent density (AD) of recycled aggregates were obtained based on the proportion of mortar area and the mortar volume, with the determination coefficients of 0.99. The results demonstrated that the proposed approach could be profitably applied to evaluate the quality of the recycled aggregates, which lays a foundation for visual identification and intelligent sorting of recycled aggregates.