bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cerebral pseudoinfarction due to venoarterial extracorporeal membrane oxygenation: A case report
Authors: Xu Mi , Yan Jue-Yue , Jin Jia-Jia , Li Tong 
Published: June 2024

BACKGROUND
Neurological complications are common in the management of venoarterial extracorporeal membrane oxygenation (VA-ECMO), with most patients requiring sedation and intubation, limiting the assessment of neurological function. There-fore, we must rely on advanced neuroimaging techniques, such as computed tomography angiography (CTA) and computed tomography perfusion (CTP). Because ECMO changes the normal blood flow pattern, it may interfere with the contrast medium in some special cases, leading to artifacts and ultimately mis-leading clinical decisions.
CASE SUMMARY
A 61-year-old man presented to a local hospital with chest tightness and pain 1 d prior to presentation. The patient was treated with VA-ECMO after sudden car-diac and respiratory arrest at a local hospital. For further treatment, the patient was transferred to our hospital. The initial consciousness assessment was not clear, and routine CTP was performed to understand the intracranial changes, which suggested a large area of cerebral infarction on the right side; however, the cerebral oxygen was not consistent with the CTP results, and the reexamination of CTA still suggested a right cerebral infarction. To identify this difference, bedside transcranial Doppler was performed, and the blood flow on both sides was different. By reducing the ECMO flow, CTP reexamination showed that the results were normal and consistent with the clinical results. On day 3, the patient was alert and showed good limb movements.
CONCLUSION
In patients with peripheral VA-ECMO, cerebral perfusion confirmed by CTP and CTA may lead to false cerebral infarction.
Ilizarov technique for treating elbow stiffness caused by myositis ossificans: A case report
Authors: Zhou Ming-Wang , Zhang Peng-Wei , Zhang An-Le , Wei Chang-Hao , Xu Yu-De , Chen Wei , Fu Zhi-Bin 
Published: June 2024

BACKGROUND
Myositis ossificans (MO) is a rare disease involving the formation of bone outside the musculoskeletal system. While surgical intervention is the main treatment approach, preventing recurrence and standardized rehabilitation are also crucial. Here, we present a surgical strategy to prevent the recurrence of MO.
CASE SUMMARY
A 28-year-old female patient was admitted for the first time for a comminuted fracture of the left olecranon. However, incorrect postoperative rehabilitation resulted in the development of elbow joint stiffness with ectopic ossification, causing a loss of normal range of motion. The patient was diagnosed with MO based on physical examination, X-ray findings, and clinical presentation. We devised a surgical strategy to remove MO, followed by fixation with an Ilizarov frame, and implemented a scientifically reasonable rehabilitation plan. The surgery lasted for 3 h with an estimated blood loss of 45 mL. A drainage tube was placed after surgery, and fluid was aspirated through ultrasound-guided puncture. The patient experienced a significant reduction in joint stiffness after surgery. In the final follow-up at 9 mouths, there was evident improvement in the range of motion of the elbow joint, and no other symptoms were reported.
CONCLUSION
The Ilizarov frame is an advantageous surgical technique for facilitating rehabilitation after MO removal. It offers benefits such as passive recovery, individualized treatment, and prompt recovery.
Natural history and surgical treatment of a giant colonic diverticulum: A case report
Authors: Bachelani Arshad M 
Published: June 2024

BACKGROUND
While diverticular disease is prevalent in the West, the formation of giant colonic diverticula is rare. To date, approximately 200 cases have been reported, with only a handful treated surgically using a minimally invasive approach. Furthermore, the natural history of giant colonic diverticula is not well documented.
CASE SUMMARY
This report describes the case of a 66-year-old man who developed a giant colonic diverticulum with primary symptoms including dull and chronic pain in the right lower quadrant at presentation. The patient had undergone several computed tomography scans of the abdomen and pelvis over the previous two years, through which the natural history of this rare entity could be retrospectively observed. The patient was successfully treated with a robot-assisted sigmoid colectomy and had an uneventful recovery with resolution of symptoms during the follow-up.
CONCLUSION
This rare case demonstrates the natural history of giant colonic diverticulum formation and supports the feasibility of robot-assisted surgery.
3D AUTOMATED VERSUS MANUAL ASSESSMENT OF ALIGNMENT IN NORMAL AND CAVUS FEET USING WEIGHT-BEARING CT SCANS: DOES IT DIFFER?
Authors: Sangoi D. , Ranjit S. , Bernasconi A. , Cullen N. , Patel S. , Welck M. , Malhotra K. 
Published: June 2024

BackgroundThe complex deformities in cavovarus feet may be difficult to assess and understand. Weight-bearing CT (WBCT) is increasingly used to evaluate complex deformities. However, the bone axes may be difficult to calculate in the setting of severe deformity. Computer-assisted 3D-axis calculation is a novel approach that may allow for more accurate assessment of foot alignment / deformity. The aim of this study was to assess differences in measurements done manually on 2D slices of WBCT versus 3D computer models in normal and cavus feet.MethodsWe retrospectively analyzed WBCT scans from 16 normal and 16 cavus feet in patients with Charcot-Marie Tooth. Eight measurements were assessed: Talus-1st metatarsal angle (axial plane), Forefoot arch angle (coronal plane), and Meary's angle, calcaneal pitch, cuneiform to floor, cuneiform to skin, navicular to floor and navicular to skin distance (sagittal plane). 2D measurements were performed manually and 3D measurements were performed using specialised software (BoneLogic, DISIOR).ResultsThere was no significant difference in the measured variables (2D manual versus 3D automated) in normal feet. In the cavus group, 3D assessment calculated increased values for the sagittal angles: Meary's 7.3 degrees greater (p = 0.004), calcaneal pitch 2.4 degrees greater (p = 0.011)), and lower values for the axial talus-1st MT angle, 10.6 degrees less (p = 0.001).ConclusionThere were no significant differences in the normal group. This suggests 3D automated techniques can reliably assess the alignment of bony axes. However, the 3D axis calculations suggest there may be greater sagittal and lesser axial deformity in cavus feet than measured by 2D techniques. This discrepancy may be on account of the rotation seen in cavovarus feet, which may not be readily assessed manually. 3D automated measurements may therefore have a role in better assessing and classifying the cavus foot which may ultimately help inform treatment algorithms.
PREVALENCE OF SYMPTOMATIC VENOUS THROMBOEMBOLISM IN PATIENTS WITH DIABETIC FEET TREATED IN TOTAL CONTACT CAST IN A TERTIARY REFERRAL DIABETIC FOOT UNIT
Authors: Kozhikunnath A. , Garg P. , Coll A. , Robinson A. HN 
Published: June 2024

IntroductionTotal contact casting (TCC) is one of the most commonly utilized modalities in the management of diabetic feet. We undertook a retrospective review to determine the prevalence of symptomatic VTE events in patients treated in a weight bearing TCC in our diabetic foot unit, and to formulate guidelines for VTE prophylaxis.MethodsElectronic records were reviewed to identify all patients treated in a TCC between 2014 and 2021. Data collection included patient demographics, comorbidities, period of immobilization in TCC, the incidence of VTE events, and any VTE prophylaxis prescribed during their period in TCC.Results549 patients were identified who had at least one episode of TCC. Mean age was 67 years (range 28 to 94 years) and the mean duration in cast was 10.2 weeks (range 0.3–46 weeks). Only 6 patients (1.1%) were prescribed chemical thrombo-prophylaxis during their period in TCC. Mean body mass index (BMI) for these patients was 32.3 (Range 18.4–58.9). Other significant comorbidities: 81% (n-444) of patients had associated cardio-vascular comorbidities; 54 % (n-296) had renal comorbidities including 22% (n-121) having had dialysis and 4.2% (n-23) with renal transplants. Eight of the 549 patients (1.5%) had suffered a VTE event of which only 2 (0.36%) were during the period of immobilization in TCC. One was a symptomatic DVT (0.18%) and the another was an asymptomatic (incidental) finding of pulmonary embolism (PE). There was no mortality related to the VTE episodes.ConclusionNICE guidelines state that one should “Consider pharmacological VTE prophylaxis for patients with lower limb immobilization”. Our study finds that patients treated in a weight bearing TCC do not require routine pharmacological VTE prophylaxis, in spite of an extended period of lower limb immobilization and significant medical comorbidities.
Tip-apex distance as a risk factor for cut-out in cephalic double-screw nailing of intertrochanteric femur fractures
Authors: Coviello Michele , Abate Antonella , Maccagnano Giuseppe , Ippolito Francesco , Nappi Vittorio , Abbaticchio Andrea M. , Caiaffa Elio , Caiaffa Vincenzo 
Published: June 2024

AimsProximal femur fractures treatment can involve anterograde nailing with a single or double cephalic screw. An undesirable failure for this fixation is screw cut-out. In a single-screw nail, a tip-apex distance (TAD) greater than 25 mm has been associated with an increased risk of cut-out. The aim of the study was to examine the role of TAD as a risk factor in a cephalic double-screw nail.MethodsA retrospective study was conducted on 112 patients treated for intertrochanteric femur fracture with a double proximal screw nail (Endovis BA2; EBA2) from January to September 2021. The analyzed variables were age, sex, BMI, comorbidities, fracture type, side, time of surgery, quality of reduction, pre-existing therapy with bisphosphonate for osteoporosis, screw placement in two different views, and TAD. The last follow-up was at 12 months. Logistic regression was used to study the potential factors of screw cut-out, and receiver operating characteristic curve to identify the threshold value.ResultsA total of 98 of the 112 patients met the inclusion criteria. Overall, 65 patients were female (66.3%), the mean age was 83.23 years (SD 7.07), and the mean follow-up was 378 days (SD 36). Cut-out was observed in five patients (5.10%). The variables identified by univariate analysis with p < 0.05 were included in the multivariate logistic regression model were screw placement and TAD. The TAD was significant with an odds ratio (OR) 5.03 (p = 0.012) as the screw placement with an OR 4.35 (p = 0.043) in the anteroposterior view, and OR 10.61 (p = 0.037) in the lateral view. The TAD threshold value identified was 29.50 mm.ConclusionOur study confirmed the risk factors for cut-out in the double-screw nail are comparable to those in the single screw. We found a TAD value of 29.50 mm to be associated with a risk of cut-out in double-screw nails, when good fracture reduction is granted. This value is higher than the one reported with single-screw nails. Therefore, we suggest the role of TAD should be reconsidered in well-reduced fractures treated with double-screw intramedullary nail.Cite this article: Bone Jt Open 2024;5(6):457–463.
A diffúz nagy B-sejtes limfóma osztályozása és kezelési lehetőségei
Authors: Gergely Lajos , Nagy Zsolt 
Published: June 2024

A diffúz nagy B-sejtes limfóma (DLBCL) a leggyakoribb agresszív non-Hodgkin limfóma. Az első vonali kezelésre nem reagáló vagy visszaeső betegek (r/r DLBCL) nagy kihívás a kezelőorvos számára. A betegséget ma a WHO2022 felosztás alapján csoportosítjuk, és rendelkezésre állnak génexpressziós profil és újgenericáiós szekvenálás (NGS) alapú felosztások, melyek segítenek az egyes esetek pontos karakterizálásában. Az első vonali kezelésben közel 20 év után a polatuzumab-vedotin alkalmazása hozta az első pozitív eredményt, több mint 6%-kal növelve a hatást. Az r/r DLBCL kezelésében forradalom ment végbe, számos CAR-T-kezelés (axi-cel, liso-cel, tisa-cel) érhető el már 2. vonaltól. Az elért eredmények lényegesen jobbak, mint eddig bármi más kezeléssel. A bispecifikus antitestek (glofitamab, epcoritamab) alkalmazásával 3. vonaltól szintén nagyon kedvező hatást tudunk elérni, úgy, hogy a kezelést bármely hematológiai kezelő centrum tudja alkalmazni. Idősebb betegeken nagyon hatásos és biztonságos a loncastuximab-teserine monoterápia, mely szignifikánsan meg tudja nyújtani ezen betegek túlélést. A tafasitamab+lenalidomid kombináció alkalmazása is jelentősen kedvezőbb eredményt adott, mint a korábbi salvage kezelések.A cikkben a szerzők igyekeznek összefoglalni mindezen újdonságokat, segítve az olvasót, hogy tájékozódni tudjon a DLBCL kezelésében elérhető legújabb kezelések között.
КОНЦЕПТУАЛЬНО-МЕТОДОЛОГИЧЕСКИЙ ПОДХОД В ОБОСНОВАНИИ УСТОЙЧИВЫХ ОРОШАЕМЫХ АГРОЛАНДШАФТОВ
Authors: Медведева Людмила Николаевна , Пахомова Антонина Александровна 
Published: June 2024

Целью исследования стало формирование концептуально-методологических подходов в обеспечении устойчивых агроландшафтов на основе адаптивных систем земледелия и комплексных мелиораций. Объекты исследования — агроландшафты, расположенные в Волго-Донском междуречье, и региональные системы орошаемого земледелия.
Материалы и методы. Основу исследования составил метаанализ результатов научных экспедиций, проводимых учеными ВНИИОЗ — филиал ФГБНУ «ФНЦ ВНИИГиМ им. А. Н. Костякова» (Волгоград) за последние годы, а также анализ статистических данных по климатическим изменениям, состоянию региональной агропродовольственной системы. Обработка материалов и расчеты проводились с помощью компьютерных программ MS Office 2010, Statistica 13.
Результаты и выводы. Результаты исследования подтверждают повышение эффективности сельскохозяйственного производства на орошаемых землях в степной зоне на основе более широкого применения инноваций и цифровых технологий. Киберэкономическое моделирование процессов, протекающих в агроландшафтах, позволило предложить адаптивно-ландшафтные системы земледелия на основе учета разных видов полива и схем севооборотов. Выделение в пространственной структуре Волго-Донского междуречья сетевого агроландшафта интенсивного промышленного садоводства в какой-то мере восполнило научный пробел в этой области знаний. Разработанные интегральные показателя устойчивости агроландшафтов позволили спрогнозировать продукционный потенциал региональных агропродовольственных систем.
СОЦИАЛЬНОЕ ЗДОРОВЬЕ КАК ОБЪЕКТ УПРАВЛЕНЧЕСКОЙ ДЕЯТЕЛЬНОСТИ
Authors: Шилкина Елена Леонидовна , Енина Виктория Валерьевна 
Published: June 2024

Цель исследования — разработка системной модели социального здоровья применительно к практике социального управления.
Методологическую базу исследования составили принципы системного, институционального, структурно-функционального и ценностно-нормативного подходов. Преобладание подходов макросоциологической парадигмы способствовало проведению анализа системных и структурных аспектов социального здоровья.
Результаты исследования. На базе модели социального действия Т. Парсонса сформирована модель социального здоровья в качестве социентальной системы, состоящей из политической, экономической, культурной и социальной подсистем. Разработана система критериев для целенаправленного управленческого воздействия в рамках каждой подсистемы.
Перспективу исследования составляет дальнейший анализ воздействия посредством управленческой деятельности на качественное состояние социального здоровья.
Character Building Of StudentsIn The Boarding School System
Authors: Ikhwandi Arifin  
Published: June 2024

The rapid development of the times marked by advances in science and technology, whether we realize it or not, it has a sharp impact on society, including adolescents and school-age children. The positive impact arising from the development of science and technology is a great hope for all levels of society. On the other hand, the emergence of negative impacts is undeniable and has recently occurred in society, including in the world of education. Cases of bullying, student fights, skipping school, actions of against the teachers, are increasingly common. This makes parents, practitioners, organizers and observers of education quite concerned and stimulated to create and emphasize education that is able to produce students who have strong character, have akhlaqul karimah.
Realizing this condition is also the responsibility of the government, the government stipulates the importance of character education in educational institutions as stated in Presidential Regulation No. 78 of 2017 concerning Strengthening Character Education. One of the efforts taken by education providers is to organize education with boarding services, namely educational services by requiring students to live in school dormitories, with the aim that the education process can run twenty-four hours, with full attention and monitoring and guidance from the boarding supervisor. With this boarding system, the school will be easier to condition students to participate in activities organized by the school, including religious education as the core of character education in theory and practice directly with the guidance of teachers in the dormitory.
Boarding system education also isolates students from socializing in the wider environment which has recently been exposed to many negative influences from the internet, social media and so on. In boarding schools, students are taught to have a strong character through a maximum educational process.
Analisis Determinasi Kebijakan Dividen Pada Perusahaan LQ45
Authors: Muhammad Nur Adli  , Utaminingtyas Tri Hesti , Khairunnisa Hera 
Published: June 2024

The purpose of this study is to test and analyze managerial ownership, profitability, investment opportunity set, and debt to equity ratio to dividend policy. This study uses secondary data sources derived from the company's annual report on companies listed in the LQ45 index on the Indonesia Stock Exchange (IDX) in 2018-2022 using purposive sampling techniques. The analysis technique used is regression analysis of panel data using Econometric Views 13 (EViews) software. The findings indicated that the managerial ownership had no bearing on dividend policy, the profitability significantly impacted dvidend policy, the investment opportunity set had no bearing on dividend policy, the debt to equity ratio significantly impacted dividend policy significantly impacted sustainability report disclosure.
Evaluating the support of pigmented lesion expert dermatologists for the use of skin self-examinations
Authors: Ingrassia Jenne , Swearingen Alyssa , Levine Amanda , Liebman Tracey N. , Stein Jennifer A. , Polsky David , Adotama Prince 
Published: June 2024

Abstract

Objectives: This study addresses the knowledge gap on optimal frequency of skin self-examinations (SSE) for skin cancer prevention in the United States. Our results offer guidance on optimal SSE practices based upon recommendations from pigmented lesion expert dermatologists, and discussion on how melanoma risk factors impact these recommendations.
Methods: We surveyed pigmented lesion expert, board-certified dermatologists who are active members of the Melanoma Prevention Working Group, between August and November 2023. The survey was anonymous and the deidentified data were analyzed qualitatively.
Results: The response rate was 64%. Nearly all dermatologists surveyed (97%) recommend SSE for patients with at least one melanoma risk factors, with the majority (64%) recommending SSE within a 1-to-3-month timeframe. For patients without identifiable risk factors, the experts in this study still recommend SSE (78%), though a consensus on frequency was not reached.
Conclusions:  Despite the lack of endorsement from the United States Preventive Services Task Force, our findings show pigmented lesion experts overwhelmingly recommend SSE. We believe targeted SSE recommendations can facilitate the detection of early-stage melanomas and have the potential to reduce melanoma morbidity.
Crouzon’s Syndrome in 7 years old child: A Comprehensive Review and Clinico-Radiological Illustration of a Case.
Authors: Sonali kajabe Sonali kajabe , Dr. Priyanka Razdan  , Dr. Rashmi Jayanna  , Dr. Swapnil Mhatre  
Published: June 2024

Crouzon's syndrome is a rare genetic disorder, described by a French neurosurgeon in 1912. It is caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. The disease is characterized by premature synostosis of coronal and sagittal sutures which begins in the first year of life. It occurs in approximately 1 in 25,000 births worldwide. Here, we report a case of this rare entity. The patient presented with brachycephaly, maxillary hypoplasia, exophthalmos, and mandibular prognathism along with dental and orbital abnormalities.
Biomimetic And Regenerative Considerations In Endodontics: A Review
Authors: Thakur Vivek , Vishal Sharma  , Vishal Sharma  , Anshu Minocha  
Published: June 2024

Biomimetics, literally means to mimic or copy what is life-like from nature. Biomimetics provides a new technique for improving our understanding of natural designs and functions, as well as new promising paths for mimicking natural processes. The first part of biomimetic dentistry is the restoration of destroyed or degenerated dental tissue, resulting in the full restoration of both functionality and appearance to the tooth. Additionally, the material utilized can repair, reproduce, or simulate missing dental tissue. This concept is very wide and has been applied in dental materials, for the regeneration of lost dental tissue from the stem cells. Regeneration approach is a form of biomimetics that promotes for the restoration of damaged tissue using tissue technology rather than the conventional method. The purpose of this review is to increase our understanding of biomimetics and regeneration factors related to lost tooth tissue in the field of endodontics.
Digital workflow in Maxillofacial Prosthodontics : An Insight
Authors: Isheta Sarkar  
Published: June 2024

Title: “Digital Workflow in Maxillofacial Prosthodontics: An Insight”

ABSTRACT
From its inception to now dentistry has made its way covering great milestones in terms of invention and precision to provide us with better working conditions and increased comfort for both clinicians and patients. To add up, is the remarkable innovation: CAD-CAM technology, which allow the dentists to provide a better and quality care to their patients. While restoring a facial defect the prosthesis should ideally be customized to put back the anatomy as accurately as possible. This process is difficult and time consuming & demands a high level of artistic skill to form a mirror image & achieve a good aesthetic match. The present time evolution of CAD/CAM is focused on methodical and swift integration and automation of the elements of design and manufacturing along with the development of new algorithms. This article reviews the development and availability of various digital technologies for the designing and manufacturing of different maxillofacial prostheses.