bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma
Authors: Chen Yeng , Lim Boon-Kiong , Hashim Onn H 
Published: August 2009

AbstractBackgroundThe general enhanced expression of α1-antichymotrypsin (ACT), clusterin (CLU), α1-antitrypsin (AAT), haptoglobin β-chain (HAP), and leucine rich glycoprotein (LRG) in the sera of patients with epithelial ovarian carcinoma (EOCa) was recently reported. In the present study, we compared the expression of the serum acute-phase proteins (APPs) in the patients according to their stages of cancer.ResultsDifferent altered stage correlative expression of the high abundance serum APPs was demonstrated in sera of the patients studied. While the expression of ACT, HAP and AAT appeared to demonstrate positive correlation with the three initial stages of the cancer, inverse correlation was apparently detected in the expression of LRG and CLU. For patients who were diagnosed with stage IV of the cancer, expression of the serum APPs did not conform to the altered progression changes.ConclusionOur results highlight the potential prognostic significance of selective high abundance serum APPs in patients with EOCa.
Delusions and belief flexibility in psychosis
Authors: Colbert S. M. , Peters E. R. , Garety P. A. 
Published: August 2009

Objectives. A defining characteristic of delusions is inflexibility. However, it is not known if this is specific to the deluded individual's thinking about delusional beliefs, or whether this might apply more generally to the thinking style of people with delusions.Design. A cross‐sectional design was employed comparing belief flexibility, belief dimensions, and extreme responding (ER) across three groups.Methods. Belief flexibility and dimensions were assessed for two types of beliefs, personally meaningful beliefs (delusional or idiosyncratic beliefs) and standard beliefs. The number of extreme responses endorsed on a questionnaire was also measured. Participants consisted of a currently deluded group (N=17), a remitted delusions group (N=17), both recruited from an early psychosis service, and a non‐clinical control group (N=35).Results. Personally meaningful beliefs, whether delusions or other idiosyncratic beliefs, were held with equal conviction and belief flexibility in the three groups. However, on the standard belief, the clinical groups showed less belief flexibility than the control group (with only the remitted group significantly so) and greater ER. Individuals who showed belief flexibility about both types of beliefs displayed less ER than those who were inflexible, and belief flexibility was related to less delusional conviction in the clinical groups.Conclusion. These results suggest that belief inflexibility and ER may be characteristics of the thinking styles of individuals with delusions, rather than being specific to the delusional beliefs themselves. This has implications for cognitive behavioural therapy, which might usefully focus on generally thinking style as a preparation for working more directly with delusional beliefs.
Oxygen Compatibility of Brass-Filled PTFE Compared to Commonly Used Fluorinated Polymers for Oxygen Systems
Authors: Herald Stephen D. , Frisby Paul M. , Davis Samuel Eddie 
Published: August 2009

Abstract
Safe and reliable seal materials for high-pressure oxygen systems sometimes appear to be extinct species when sought out by oxygen systems designers. Materials that seal well are easy to find, but these materials are typically incompatible with oxygen, especially in cryogenic liquid form. This incompatibility can result in seals that leak, or much worse, seals that easily ignite and burn during use. Scientists at the Materials Combustion Research Facility (MCRF), part of NASA/Marshall Space Flight Center, are constantly searching for better materials and processes to improve the safety of oxygen systems. One focus of this effort is improving the characteristics of polymers used in the presence of an oxygen enriched environment. Very few systems can be built which contain no polymeric materials; therefore, materials which have good impact resistance, low heat of combustion, high auto-ignition temperature, and those that maintain good mechanical properties are essential. The scientists and engineers at the MCRF, in cooperation with seal suppliers, are currently testing a new formulation of polytetrafluoroethylene (PTFE) with brass filler. This brass-filled PTFE is showing great promise as a seal and seat material for high-pressure oxygen systems. Early research has demonstrated very encouraging results, which could rank this material as one of the best fluorinated polymers ever tested. This paper will compare the data obtained for brass-filled PTFE with other fluorinated polymers, such as TFE-polytetrafluoroethylene (PTFE), polychlorotrifluoroethylene 81, Viton® A, Viton® A-500, Fluorel®, and Algoflon®. A similar metal-filled fluorinated polymer, Salox-M®, was tested in comparison to brass-filled PTFE to demonstrate the importance of the metal chosen and relative percentage of filler. General conclusions on the oxygen compatibility of this formulation are drawn, with an emphasis on comparing and contrasting the materials performance to the performance of the current state-of-the-art oxygen compatible polymers.
Virtuelle Raumluftströmungssensoren zur Regelung der thermischen BehaglichkeitVirtual Airflow Sensors for Thermal Comfort Control
Authors: Felgner Felix 
Published: August 2009

Zusammenfassung
Diese Arbeit schafft eine Grundlage für bessere thermische Behaglichkeit in klimatisierten Räumen. Es wird eine Methodik entwickelt, mit der die Raumluftströmung in Echtzeit geschätzt werden kann. Basierend auf mathematischen Modellen berechnen virtuelle Sensoren die Lufttemperatur und -geschwindigkeit an beliebigen Orten im Raum. Zu diesem Zweck wird ein rechentechnisch effizientes, datenbasiertes Raumluftströmungsmodell entwickelt. Um den Komfortgewinn zu demonstrieren, der mit Hilfe der neuen virtuellen Sensoren erreichbar ist, werden Ergebnisse einer Regelung des Predicted Mean Vote (PMV gemäß Standard ISO 7730) in einem realen Konferenzraum gezeigt.
A Case-Based Approach to Decision AnalysisEin fallbasiertes Verfahren zur Beschlussanalyse
Authors: Xiong Ning 
Published: August 2009

Abstract
This paper proposes a novel approach for integrating case-based reasoning (CBR) and decision theory for casebased decision analysis. CBR is employed as a methodology to reason from previous cases for building a decision model given a current situation, while decision theory is applied to the decision model learnt from previous cases to identify the most promising, secured, and rational choices. We have also tackled the issue of imprecise utility in individual cases and explained how fuzzy decision analysis can be conducted when case specific utilities are represented with fuzzy data.
Modellierung und Simulation vernetzter Automatisierungs- und Regelungssysteme in ModelicaModeling and Simulation of Networked Automation and Control Systems in Modelica
Authors: Frey Georg , Liu Liu 
Published: August 2009

Zusammenfassung
Automatisierungssysteme werden zunehmend in vernetzten Strukturen realisiert. Die Untersuchung solcher Systeme durch Simulation erfordert Modelle, die das Zeitverhalten der Automatisierungsgeräte und der eingesetzten Netzwerke beschreiben. Im vorliegenden Beitrag wird eine entsprechende Bibliothek vorgestellt, die in der Modellierungssprache Modelica entwickelt wurde und beispielsweise im Simulationswerkzeug Dymola eingesetzt werden kann. Die Anwendung der entwickelten Modelle zur Antwortzeitanalyse im offenen Kreis sowie zur Analyse vernetzter Regelungssysteme im geschlossenen Kreis wird anhand von Beispielen illustriert. Schließlich wird ein Ansatz vorgestellt, der es erlaubt den Aufwand zur Simulation der entstehenden hybriden Modelle zu reduzieren.
A New Compositional Model for Hydraulic Fracturing With Energized Fluids
Authors: Friehauf Kyle , Sharma Mukul M. 
Published: August 2009

Summary
Traditional fracturing models regard fracturing fluids as a single-component, single-phase fluid. This assumption is clearly incorrect for energized fluids where phase changes and mass transfer between phases play important roles in controlling fluid rheology, leakoff, and fracture geometry. A model is developed to simulate hydraulic fracturing with energized fluids. Compositional balances allow tracking of the changes in phase behavior and fluid properties, such as rheology and multiphase leakoff. An energy balance is implemented in order to consider temperature changes during fracturing. Phase behavior has been taken into account through an equation-of-state (EOS) formulation. These compositional- and phase-behavior effects are coupled with a geomechanical model for fracture propagation.
It is shown that phase behavior and leakoff can change the composition and fluid rheology in the fracture significantly. This has a dramatic effect on the fracture geometry. Phase-behavior changes are coupled closely to the temperature and pressure changes in the fracture. The temperature, phase behavior, and partitioning of components in the liquid and gas phases have a significant effect on fracture dimensions. For example, shorter and wider fractures can be obtained by foaming an energized fluid. With the model presented, these temperature, pressure, and composition changes can now be modeled accurately and incorporated into the fracture growth and geometry.
Systemic Therapies for Pediatric Atopic Dermatitis: A Review for the Primary Care Physician
Authors: Shaw Maren G. , Burkhart Craig N. , Morrell Dean S. 
Published: August 2009

CME Educational Objectives

1.
Review the currently used systemic therapies for severe pediatric atopic dermatitis.

2.
Summarize the published data on systemic therapies used in the treatment of severe pediatric atopic dermatitis.

3.
Provide a progressive strategy for approaching the use of systemic modalities in severe pediatric atopic dermatitis.
Genetic Syndromes: From Clinical Suspicion to Referral to Diagnosis
Authors: Shur Natasha , Abuelo Dianne 
Published: August 2009

CME Educational Objectives

1.
Name the currently suggested diagnostic categories for genetic disorders.

2.
Explain how categorization of patients into diagnostic groupings allows for a tiered approach to differential diagnosis and testing.

3.
Recognize the most appropriate referral criteria for further genetic consultation and testing in the pediatric population.
Expanded Newborn Screening: An Update for Pediatricians
Authors: Barbouth Deborah , Morales Ana , Villalba Ricardo 
Published: August 2009

CME Educational Objectives

1.
Name current recommendations for newborn screening.

2.
Apply evidence supporting newborn screening as a means for prevention of irreversible morbidity and mortality.

3.
Identify available newborn screening resource for parents and health care providers.
Delayed Onset Thigh Compartment Syndrome Secondary to Contusion
Authors: Joglekar Siddharth B. , Rehman Saqib 
Published: August 2009

While thigh compartment syndrome is relatively uncommon, it can occur in various situations. Multiple reports document thigh contusions as a cause of acute compartment syndrome; however, compartment syndrome of the thigh presenting primarily in a delayed fashion secondary to a contusion has not been described. This article reports a case of thigh compartment syndrome.
A 39-year-old man sustained a left thigh contusion while playing basketball. He continued to play and also worked at the office over the next 2 days. Fifty-two hours postinjury, he developed severe pain in the thigh after a long walk. Increased swelling of the thigh followed, with numbness in the anterolateral thigh and pain with knee motion. He presented 60 hours postinjury with a compartment syndrome, and a lateral decompressive fasciotomy of the thigh was performed 62 hours postinjury. The wound was closed after 5 days. Three months postoperatively, the patient returned to playing basketball with no deficits.
Treatment of established compartment syndrome in such cases is controversial, with some reports recommending nonoperative management. Contusion-related compartment syndromes are frequently associated with intramuscular bleeding in the involved compartment, which may accumulate slowly or worsen with further activity. Guidelines regarding return to sports need to be established in individuals sustaining severe contusions during sports-related activities to prevent compartment syndrome. Any individual sustaining such an injury should be under surveillance for delayed onset symptoms or signs of this potentially devastating syndrome.
Aneurysmal Bone Cyst of the Fifth Metacarpal
Authors: Ozyurek Selahattin , Rodop Osman , Kose Ozkan , Cilli Feridun , Mahirogullari Mahir 
Published: August 2009

Aneurysmal bone cyst is a rare, rapidly growing, and destructive benign bone tumor that even more rarely involves the bones of the hand. Various treatment options for aneurysmal bone cyst have been reported in the literature, but controversy exists regarding optimal treatment. Due to its rarity in the hand, no evidence-based treatment regimen has been established.
A 21-year-old man presented with a history of pain and local swelling over his fifth metacarpal of 5 months' duration. Physical and radiographic examination of the hand was consistent with aneurysmal bone cyst. After biopsy, pathologic examination confirmed the diagnosis of aneurysmal bone cyst. En-block resection of the tumor and autologous bicortical strut graft fixation with Kirschner wires was performed. The hand was immobilized in a short arm cast for 3 weeks after the patient received 3 weeks of physiotherapy. Kirschner wires were removed 6 weeks postoperatively. Excellent clinical and functional results were obtained with no recurrence after 3 years of follow-up with en-block resection and reconstruction with iliac crest graft. Radiographic examination demonstrated the osseous integration of the graft with no signs of recurrence.
Although treatment should be planned individually according to lesion site and size and to patient age, we suggest en-block resection to prevent recurrence and secondary surgical interventions particularly in cases with no articular involvement.
Characterization of FIBCD1 as an Acetyl Group-Binding Receptor That Binds Chitin
Authors: Schlosser Anders , Thomsen Theresa , Moeller Jesper B. , Nielsen Ole , Tornøe Ida , Mollenhauer Jan , Moestrup Søren K. , Holmskov Uffe 
Published: August 2009

Abstract
Chitin is a highly acetylated compound and the second most abundant biopolymer in the world next to cellulose. Vertebrates are exposed to chitin both through food ingestion and when infected with parasites, and fungi and chitin modulate the immune response in different directions. We have identified a novel homotetrameric 55-kDa type II transmembrane protein encoded by the FIBCD1 gene and highly expressed in the gastrointestinal tract. The ectodomain of FIBCD1 is characterized by a coiled-coil region, a polycationic region and C-terminal fibrinogen-related domain that by disulfide linkage assembles the protein into tetramers. Functional analysis showed a high-affinity and calcium-dependent binding of acetylated components to the fibrinogen domain, and a function in endocytosis was demonstrated. Screening for ligands revealed that the FIBCD1 is a high-affinity receptor for chitin and chitin fragments. FIBCD1 may play an important role in controlling the exposure of intestine to chitin and chitin fragments, which is of great relevance for the immune defense against parasites and fungi and for immune response modulation.
Early Triggering of Exclusive IFN-γ Responses of Human Vγ9Vδ2 T Cells by TLR-Activated Myeloid and Plasmacytoid Dendritic Cells
Authors: Devilder Marie-Claire , Allain Sophie , Dousset Christelle , Bonneville Marc , Scotet Emmanuel 
Published: August 2009

Abstract
γδ T cells, a major innate-like T cell subset, are thought to play in vivo an important role in innate and adaptive immune responses to various infection agents like parasites, bacteria, or viruses but the mechanisms contributing to this immune process remain ill defined. Owing to their ability to recognize a broad set of microbial molecular patterns, TLRs represent a major innate pathway through which pathogens induce dendritic cells (DC) maturation and acquisition of immunostimulatory functions. In this study, we studied the effects of various TLR ligands on the activation of human Vγ9Vδ2 T cells, a main human γδ PBL subset, which has been recently involved in the licensing of mycobacteria-infected DC. Both TLR3 and TLR4, but not TLR2 ligands, induced a rapid, strong, and exclusive IFN-γ production by Vγ9Vδ2 T cells. This γδ subset contributed to a large extent to the overall PBL IFN-γ response induced after short-term TLR stimulation of human PBMC. Importantly, this phenomenon primarily depended on type I IFN, but not IL-12, produced by monocytic DC upon TLR engagement. Vγ9Vδ2 T cells were similarly activated by plasmacytoid DC upon TLR8/9 activation or Yellow Fever virus infection. Moreover TLR-induced Vγ9Vδ2 IFN-γ noncytolytic response led to efficient DC polarization into IL-12p70-producing cells. Our results support an adjuvant role played by Vγ9Vδ2 T cells along microbial infections through a particular cross-talk with pathogen-associated molecular patterns-activated DC. Moreover they provide new insights into the mechanisms underlying functional activation of this unique peripheral innate-like T cell subset during viral infections.
Translation of variables and implementation of efficient logic‐based techniques in the MINLP process synthesizer MIPSYN
Authors: Ropotar Marcel , Kravanja Zdravko 
Published: August 2009

AbstractThis article describes alternative GDP formulation and convex hull representations for process synthesis problems and their implementation in a unique MINLP process synthesizer MIPSYN. A special translation of variables in mixed‐integer, relaxed, and logic‐based variations has been proposed, which enables modeling and solving process alternatives in a narrowed lifted space of variables, defined by nonzero lower and upper bounds. Based on these translation variations, alternative formulations have been developed for convex hulls, multiple‐term generalized disjunctive programming problems, and logic‐based outer‐approximation algorithm, all of them being specialized for the synthesis of process flowsheets. Several studies were performed and three different large‐scale synthesis problems were solved to test the performance and efficiency of different formulations. This initial research indicates that the proposed alternative convex hull representation usually outperforms the conventional one when solving both MILP and NLP steps in highly combinatorial MINLP process networks problems. © 2009 American Institute of Chemical Engineers AIChE J, 2009
Enhancing therapeutic loading and delaying transport via molecular imprinting and living/controlled polymerization
Authors: Vaughan Asa D. , Zhang Jeney B. , Byrne Mark E. 
Published: August 2009

AbstractThis work demonstrates for the first time molecular imprinting using a “living/controlled” polymerization (LCP) strategy to enhance template loading/affinity and delay release in weakly crosslinked gels. Two gel systems were studied: poly(DEAEM‐co‐HEMA‐co‐PEG200DMA) gels imprinted for diclofenac sodium and poly(MAA‐co‐EGDMA) gels imprinted for ethyl adenine‐9‐acetate. Experimental evidence confirms that template diffusion coefficients within imprinted gels can be heavily influenced by template binding affinity. Recognition studies revealed significant increases in template loading/affinity with large increases in loading for LCP, and dynamic template release studies showed that imprinting via LCP extends the template release profile by twofold over that of imprinting via conventional free‐radical polymerization techniques and fourfold over the control network (less Fickian and toward zero‐order release with a profile coefficient of 0.70). Analysis of reaction kinetics indicated that LCP with reversible termination events increases the chemically controlled chain propagation mechanism, and that binding sites are formed during this phase of the polymerization. © 2009 American Institute of Chemical Engineers AIChE J, 2010
Total projection to latent structures for process monitoring
Authors: Zhou Donghua , Li Gang , Qin S. Joe 
Published: August 2009

AbstractPartial least squares or projection to latent structures (PLS) has been used in multivariate statistical process monitoring similar to principal component analysis. Standard PLS often requires many components or latent variables (LVs), which contain variations orthogonal to Y and useless for predicting Y. Further, the X‐residual of PLS usually has quite large variations, thus is not proper to monitor with the Q‐statistic. To reduce false alarm and missing alarm rates of faults related to Y, a total projection to latent structures (T‐PLS) algorithm is proposed in this article. The new structure divides the X‐space into four parts instead of two parts in standard PLS. The properties of T‐PLS are studied in detail, including its relationship to the orthogonal PLS. Further study shows the space decomposition on X‐space induced by T‐PLS. Fault detection policy is developed based on the T‐PLS. Case studies on two simulation examples show the effectiveness of the T‐PLS based fault detection methods. © 2009 American Institute of Chemical Engineers AIChE J, 2010
Cellulose triacetate‐based polymer gel electrolytes
Authors: Lee Jung Min , Nguyen Dinh Quan , Lee Seul Bee , Kim Honggon , Ahn Byoung Sung , Lee Hyunjoo , Kim Hoon Sik 
Published: August 2009

AbstractNew composite polymer gels were obtained from cellulose triacetate (CTA), N‐methyl‐N′‐propylpyrrolidinium bis(trifluoromethanesulfonyl)imide (Pyr1,3TFSI), and lithium bis(trifluoromethanesulfonyl)imide (LiTFSI). Analysis by differential scanning calorimeter and scanning electron microscope showed that the ionic gel consisting of CTA, Pyr1,3TFSI, and LiTFSI formed a completely homogeneous phase at the molar ratio of CTA/Pyr1,3TFSI/LiTFSI = 1/3/1.5. The ionic conductivity of the polymer gel was significantly enhanced by the presence of LiTFSI. FTIR study strongly implies that the interaction of lithium ion with the carbonyl group of CTA could be responsible for the increase in conductivity. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
One‐step synthesis of polyaniline nanofibers decorated with silver
Authors: Jia Qingming , Shan Shaoyun , Jiang Lihong , Wang Yaming 
Published: August 2009

AbstractPolyaniline (PANI)/silver (Ag) nanocomposites containing PANI nanofibers decorated with well‐dispersed Ag nanoparticles were obtained with interfacial polymerization. It was interesting that silver nitride affected not only the diameter and crystallinity of the PANI nanofibers but also their room‐temperature conductivity. The conductivity increased with increasing Ag loading up to 10 (molar ratio of aniline to silver nitride), but the conductivity moderately decreased with further increasing Ag loading. Scanning electron microscopy and X‐ray diffraction analysis results indicate that the diameter of the PANI nanofibers became smaller and smaller, and their crystallinity got better and better with increasing Ag loading. However, Fourier transform infrared analysis proved that the balance of oxidized and reduced units of PANI became big with increasing Ag loading, which may have resulted in the decreasing conductivity of PANI. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010