bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy
Authors: van den Berg Manon G. A. , Rasmussen-Conrad Ellen L. , Wei Koko H. , Lintz-Luidens Heleen , Kaanders Johannes H. A. M. , Merkx Matthias A. W. 
Published: May 2010

Clinical research shows that nutritional intervention is necessary to prevent malnutrition in head and neck cancer patients undergoing radiotherapy. The objective of the present study was to assess the value of individually adjusted counselling by a dietitian compared to standard nutritional care (SC). A prospective study, conducted between 2005 and 2007, compared individual dietary counselling (IDC, optimal energy and protein requirement) to SC by an oncology nurse (standard nutritional counselling). Endpoints were weight loss, BMI and malnutrition (5 % weight loss/month) before, during and after the treatment. Thirty-eight patients were included evenly distributed over two groups. A significant decrease in weight loss was found 2 months after the treatment (P = 0·03) for IDC compared with SC. Malnutrition in patients with IDC decreased over time, while malnutrition increased in patients with SC (P = 0·02). Therefore, early and intensive individualised dietary counselling by a dietitian produces clinically relevant effects in terms of decreasing weight loss and malnutrition compared with SC in patients with head and neck cancer undergoing radiotherapy.
High latitude and marine diet: vitamin D status in elderly Faroese
Authors: Dalgård Christine , Petersen Maria Skaalum , Schmedes Anne V. , Brandslund Ivan , Weihe Pal , Grandjean Philippe 
Published: May 2010

Human subjects obtain their vitamin D from the diet, especially from marine food, and from endogenous synthesis following cutaneous sun exposure. The risk of an insufficient vitamin D synthesis is increased in northern populations, but it may be counteracted by a high intake of marine food in fishing populations, e.g. at the Faroe Islands. We examined the vitamin D status and its statistical determinants in a cross-sectional study of 713 elderly Faroese aged 70–74 years, about two-thirds of all the eligible residents in this age group. Clinical examination included measurement of body weight and height, and marine food intake was estimated using a questionnaire. We measured serum 25-hydroxyvitamin D3 (S-25(OH)D3) by LC-MS/MS in 669 of the 713 subjects in whom sufficient serum was available. Of the population, 19 % had S-25(OH)D3 concentrations < 25 nmol/l, and only 10·3 % of the population had S-25(OH)D3 concentrations >80 nmol/l. In a logistic regression analysis, BMI < 30 kg/m2, blood sampling in summer season, eating pilot whale blubber more than once per month and female sex were positively associated with vitamin D levels >80 nmol/l. The high prevalence of low vitamin D levels among the elderly Faroese population reflects the low skin synthesis during most months of the year, which is caused by the limited sun exposure and insufficient benefits from marine diet. Thus, even in a population with a high intake of marine food, the northern latitude causes a low vitamin D status. Efforts to improve vitamin D status in this population are warranted.
Consistency of vitamin and/or mineral supplement use and demographic, lifestyle and health-status predictors: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort
Authors: Li Kuanrong , Kaaks Rudolf , Linseisen Jakob , Rohrmann Sabine 
Published: May 2010

Cross-sectional studies suggest that dietary supplement use is associated with favourable demographic and lifestyle factors and certain health conditions. However, factors that affect the consistency of supplement use have not been investigated in prospective cohort studies. The aim of the present study was to seek baseline demographic, lifestyle and health-status predictors of subsequent consistent vitamin and/or mineral supplement use. A total of 8968 men and 10 672 women of the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort, who answered the supplement-use questions in the baseline survey and two follow-up surveys, were categorised into three groups: consistent, inconsistent and never users. At baseline, 28·5 % of men and 38·6 % of women reported vitamin and/or mineral supplement use. After a median follow-up of 8·5 years, 14·6 % of men and 22·9 % of women were consistent users. During follow-up, 36·0 % of male and 26·6 % of female initial users stopped supplement use, whereas 27·8 % of male and 39·4 % of female initial non-users started supplement use. Women were more likely to be consistent users than men. Older age ( ≥ 50 years), lower BMI ( < 25 kg/m2) and self-reported hyperlipidaemia were common predictors of consistent use for both sexes. Additional predictors included higher educational level for men, and being more physically active and higher lifetime alcohol consumption for women. Consistent users had the highest intake of dairy products, fish, fruits and vegetables, and wine but the lowest intake of total meat. We concluded that supplement use is a fairly unstable behaviour in free-living individuals. Individuals with a favourable lifestyle and healthier diet are more likely to show consistent supplementation.
La notion de problème moteur principal en contexte de recherche (première partie)
Authors: Lacharité Normand 
Published: May 2010

Un problème est dit ici «mouvoir» la recherche, quand c'est sur lui que se concentre l'énergie du chercheur et que c'est son traitement qui fait «avancer» la recherche.Une entreprise de recherche, une « e-r »,commej'écrirai souvent, est considérée ici comme une unité individuée et je postule qu'il y a toujours au moins un « niveau » où l'on peut se placer pour qu'il soit légitime de considérer une e-r comme une unité individuée.
McTaggart, Mereology, Substance and Change
Authors: Rankin K. W. 
Published: May 2010

McTaggart maintained that, without the kind of change (henceforth A-change) which events undergo in passing from the future through the present into the past, how things are would be fundamentally different from how they appear. More particularly(1) Without A-change there could be no change at all (#311).(2) Without any change there could be no time (#309).(3) Without A-change there could be no time (#312).
Commerce et diplomatie dans des sociétés sans Léviathan
Authors: Pestieau Joseph 
Published: May 2010

Dans cet article, j'envisagerai quelques voies par lesquelles des sociétés dites primitives surent éviter et la soumission à l'État et la guerre généralisée.On comprend que pour opposer un front commun à leurs ennemis, des hommes soient amenés à s'allier et, pour ce faire, échangent de bons precédés, des biens et des femmes. Ainsi, les nécessités de la guerre entraîneraient la formation d'alliances.
The Principle of Continuity and the Evaluation of Theories
Authors: Seager William 
Published: May 2010

Perhaps the Clearest and most impressive use of the Principle of Continuity by Leibniz in the evaluation of a theory is that offered in refutation of the Cartesian laws of motion, as given in his Critical Remarks Concerning the General Part of Descartes' Principles. With regard to the Cartesian laws of impact Leibniz says:On Article 49. Rule 4. If B, which is moving, is smaller than C, which is at rest, B will be reflected with the velocity it had before the shock while C will remain at rest.
The Leninist Theory of Perception
Authors: Goldstick D. 
Published: May 2010

In the standard English-language reference work, The Encyclopedia of Philosophy, edited by Paul Edwards (New York and London, 1967), we find the following blunt statement on the subject of “orthodox Marxism's” theory of knowledge:Its epistemology is naive representationism.The use of the word “naive” will alert the reader to the unsurprising fact that the reference here is a definitely unfriendly one. More interesting is the way in which this characterization, based on an interpretation of Lenin's Materialism and Empirio-Criticism, has become generally accepted in English-speaking philosophical circles over the past forty years. The purpose of the present article is to explain the representationalist interpretation, challenge it in favour of an alternative reading of Lenin's text, and make some substantive comments on issues arising from the philosophical debate between the representationalist and anti-representationalist positions outlined.
On the Third Attempted Definition of Knowledge, Theaetetus 201c–210b
Authors: Yoh May 
Published: May 2010

There seem to be as many interpretations of the Theaetetus (Tht.) 201c–210b as there are scholars who care to interpret it. This, of course, is not surprising. As Cherniss well puts it,the fascinating and perplexing history of Platonic interpretation…has been so largely a series of insistently charitable efforts on the part of Western philosophers and their acolytes, each to baptise Plato in his particular faith — having shriven him first, of course, by interpreting the heresies out of his works.
Animals and Morality
Authors: Monticone George T. 
Published: May 2010

Somewhere in Africa or Asia a band of unusual apes leaves the safety of the trees in the early morning light and stealthily approaches a grassland waterhole. A wounded antelope is sighted and the males, approaching quietly from all sides, spring to action. The thrashing animal is quickly subdued with rocks and clubs. Chunks of meat are ripped from the carcass and the band quickly retreats to the forest. All eat well and they multiply. The weapon using primate had arrived – the ancestor of homo sapiens.The above scenario depicts what some of the best evidence of biology and anthropology suggests concerning the origin of man. The evolutionary forerunners of homo sapiens probably diverged from primitive ape stock in becoming co-operative, systematic carniverous users of weapons. Perhaps modern man would not have evolved had it not been for this development, and the most highly evolved primate of the modern age would have been arboreal, primarily vegetarian apes.
The Causation Recipe
Authors: Freundlich Yehudah 
Published: May 2010

In a Recent article [9], Alexander Rosenberg attacks the “manipulative” view of causation as being unilluminating and as being beset with difficulties. As a proponent of that view [3], I have felt it necessary to take up cudgels in its defence.Rosenberg's criticisms are directed at Gasking's version of this view [5]. Gasking's recipe for causation is, “one says ‘A causes B’ in cases where one could produce an event of the A sort as a means to producing one of the B sort” (p. 485). Here it is taken for granted that we have general manipulative techniques for producing events of the A sort and that this is implicitly assumed when one speaks of A as a cause. There is one qualification to this formula for causes which arises from the necessity for individuating processes, namely, that, for A to be the cause of B, it must not always lead to B (for then the technique for producing A would also be a B-producing one), but only in special cases.
Implications of faecal removal by dung beetles for scat surveys in a fragmented landscape of the Brazilian Amazon
Authors: Norris Darren , Michalski Fernanda 
Published: May 2010

AbstractMonitoring rare and elusive species for effective management and conservation is particularly challenging and often demands the development of specialized techniques. Scat surveys have been applied to monitor a variety of rare species but relatively little attention has been given to the development of appropriate sampling designs. To determine if scat surveys could be applied to compare the distribution of species across three habitats of a fragmented region in the Brazilian Amazon, the removal of human (n = 27) and jaguar (n = 27) scat samples in forest, riparian corridor and pasture habitats was recorded for 24 hours. Dung beetles were responsible for removing the majority of samples (71%) and a generalized linear mixed effect model revealed significant influence of habitat and scat type on removal probability, with forest and riparian corridors having higher removal compared with samples in pasture habitats. Although non-invasive scat surveys can potentially address fundamental broad-scale conservation and management questions, our results demonstrate that scat surveys in the tropics must account for differences in scat removal rates between habitats and target species before conclusions can be drawn regarding patterns of habitat use.
Production and immunological characterization of a recombinant subunit of aLoa loapolyprotein antigen
Authors: AZZIBROUCK G. BLAMPAIN , AKUE J. P. , LENOBLE D. RICHARD 
Published: May 2010

SUMMARYDiagnosis of loiasis and analysis of the specific immune response are limited by a paucity of parasite material. To circumvent this problem, aLoa loaantigen has been expressed in a prokaryote vector (pTrcHis). Immunization of Balb/c mice with this soluble recombinant protein produced a strong antibody response, with antibodies recognizing 2 major bands of 38 and 20 kDa in a native crude extract ofLoa loaadult worms and microfilariae on Western blots. The target molecule was located mainly in the hypodermis and cuticle of the adult worm. Analysis of human IgG subclasses against this antigen by enzyme-linked immunosorbent assay (ELISA) showed IgG1, IgG2 and IgG3 but not IgG4 reactivity. IgG2 against this recombinant antigen was 100% specific for loiasis when tested against samples from European donor individuals. The same IgG2 antibodies showed 91% specificity for loiasis by comparison withWuchereria bancrofti,Onchocerca volvulus,Mansonnella perstansand other helminth infections. Furthermore, the IgG2 antibody level correlated with the density ofLoa loamicrofilariae (r=0·400;P=0·02). This recombinant 15r3 molecule and specific IgG2 assay may be useful for monitoring control programmes.
Exploiting the heterogeneous drop-off rhythm of Amblyomma variegatum nymphs to reduce pasture infestation by adult ticks
Authors: STACHURSKI F. , ADAKAL H. 
Published: May 2010

SUMMARYTick distribution depends on the drop-off rhythm of the previous stage and on the suitability for tick survival of the environment where they are disseminated. Studies were implemented in Burkina Faso to assess detachment pattern of engorged Amblyomma variegatum nymphs. Experiments were carried out with naturally infested cattle kept in a paddock or monitored when grazing community pasture. In the pasture, 80% of the nymphs detached between 14.00 h and 17.00 h while less than 25% did so in the paddock. Further investigation was implemented to assess whether the density of adult ticks might be modified by herd management. During the early dry season, zebus grazed in 4 plots fenced in natural savannahs and fallows. Two of the plots were used in the morning and the two others in the afternoon. Six months later, zebus were put in these plots, in turn, on 9 occasions. The number of A. variegatum adults picked up by the cattle in each plot was highly variable: they captured more ticks in the plots installed on good lush savannah and 3-fold more ticks in those where the herd had grazed in the afternoon during the previous dry season. An integrated tick control strategy taking these results into account is proposed.
Heat-shock protein 70 PCR-RFLP: a universal simple tool for Leishmania species discrimination in the New and Old World
Authors: MONTALVO A. M. , FRAGA J. , MONZOTE L. , MONTANO I. , DE DONCKER S. , DUJARDIN J. C. , VAN DER AUWERA G. 
Published: May 2010

SUMMARYIntroduction. Species typing in leishmaniasis gains importance in diagnostics, epidemiology, and clinical studies. A restriction fragment length polymorphism (RFLP) assay of PCR amplicons from a partial heat-shock protein 70 gene (hsp70) had been described for the New World, allowing identification of some species. Methods. Based on an initial in silico analysis of 51 hsp70 sequences, most of which we recently determined in the frame of a phylogenetic study, species-specific restriction sites were identified. These were tested by PCR-RFLP on 139 strains from 14 species, thereby documenting both inter- and intra-species variability. Results. Our assay could identify Leishmania infantum, L. donovani, L. tropica, L. aethiopica, L. major, L. lainsoni, L. naiffi, L. braziliensis, L. peruviana, L. guyanensis, and L. panamensis by applying 2 subsequent digests. L. mexicana, L. amazonensis, and L. garnhami did not generate species-specific restriction fragment patterns. Conclusion. Currently no assay is available for global Leishmania species discrimination. We present a universal PCR-RFLP method allowing identification of most medically relevant Old and New World Leishmania species on the basis of a single PCR, obviating the need to perform separate PCRs. The technique is simple to perform and can be implemented in all settings where PCR is available.
Current status of vaccination against African trypanosomiasis
Authors: MAGEZ STEFAN , CALJON GUY , TRAN THAO , STIJLEMANS BENOÎT , RADWANSKA MAGDALENA 
Published: May 2010

SUMMARYAnti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigentic variation of the parasite surface coat has been considered the major obstacle in the development of a functional vaccine, recent research into the biology of B cells has indicated that the problems might go further than that. This paper reviews past and current attempts to design both anti-trypanosome vaccines, as well as vaccines directed towards the inhibition of infection-associated pathology.
The evolution of metabolic profiling in parasitology
Authors: HOLMES E. 
Published: May 2010

SUMMARYThe uses of metabolic profiling technologies such as mass spectrometry and nuclear magnetic resonance spectroscopy in parasitology have been multi-faceted. Traditional uses of spectroscopic platforms focused on determining the chemical composition of drugs or natural products used for treatment of parasitic infection. A natural progression of the use of these tools led to the generation of chemical profiles of the parasite inin vitrosystems, monitoring the response of the parasite to chemotherapeutics, profiling metabolic consequences in the host organism and to deriving host-parasite interactions. With the dawn of the post-genomic era the paradigm in many research areas shifted towards Systems Biology and the integration of biomolecular interactions at the level of the gene, protein and metabolite. Although these technologies have yet to deliver their full potential, metabolic profiling has a key role to play in defining diagnostic or even prognostic metabolic signatures of parasitic infection and in deciphering the molecular mechanisms underpinning the development of parasite-induced pathologies. The strengths and weaknesses of the various spectroscopic technologies and analytical strategies are summarized here with respect to achieving these goals.
Formation control and trajectory tracking of mobile robotic systems – a Linear Algebra approach
Authors: Rosales Andrés , Scaglia Gustavo , Mut Vicente , di Sciascio Fernando 
Published: May 2010

SUMMARYA novel approach for trajectory tracking of a mobile-robots formation by using linear algebra theory and numerical methods is presented in this paper. The formation controller design is based on the formation states concept and the dynamic model of a unicycle-like nonholonomic mobile robot. The proposed control law designed is decentralized and scalable. Simulations and experimental results confirm the feasibility and the effectiveness of the proposed controller and the advantages of using the dynamic model of the mobile robot. By using this new strategy, the formation of mobile robots is able to change its configuration (shape and size) and follow different trajectories in a precise way, minimizing the tracking and formation errors.
Poverty and the use of destructive fishing gear near east African marine protected areas
Authors: CINNER J. E. 
Published: May 2010

SUMMARYPoverty may be an important influence on the exploitation of marine resources in tropical developing countries. A number of studies have hypothesized that destructive fishing gears, which can degrade habitat, capture high proportions of juvenile fish and ultimately lead to reduced yields, are primarily used by the poorer segments of society. However, few studies have empirically tested this relationship. This paper examines relationships between the use of destructive seine nets and thirteen socioeconomic conditions in communities adjacent to three peri-urban marine protected areas in east Africa. Fishers using destructive gears were younger, less likely to have capital invested in the fishery, had lower fortnightly expenditures and were poorer in two multivariate indices of material style of life. Based on the two multivariate material style of life indices, a binary logistic regression model classified whether fishers used destructive gears with almost 70% accuracy. These findings are broadly consistent with the literature on poverty traps, which are situations in which the poor are unable to mobilize the resources required to overcome low-income situations and consequently engage in behaviour that may reinforce their own poverty. Managers aiming to reduce destructive gear use may need to partner with civil society and donors to help break poverty traps.
RAGE and Aβ Immunoglobulins: Relation to Alzheimer’s disease-related cognitive function
Authors: MITCHELL MEGHAN B. , BUCCAFUSCO JERRY J. , SCHADE ROSANN F. , WEBSTER SCOTT J. , MRUTHINTI SHYAMALA , HARRELL DEAN U. , GULATI NIDHI K. , MILLER L. STEPHEN 
Published: May 2010

AbstractThe immunoglobulins (IgGs) for beta amyloid (Aβ) and receptors for the advanced glycation end products (RAGE) have previously been shown to be related to memory and language measures in a mixed neurological sample of older adults. In this study, we examined group differences in Aβ and RAGE IgGs, as well as the relationship between both IgGs and cognitive performance in nondiabetic older adults with normal cognition, mild cognitive impairment (MCI), and probable Alzheimer’s disease (AD). We found RAGE and Aβ levels to be elevated in some AD participants, leading to significant AD–control group differences. While there was an overall correlation between both IgG levels and global cognition across all three groups, this relationship was largely attributable to group differences in cognition, highlighted by considerable variability within groups in the relationship between IgG levels and cognition. While findings do not support a consistent relationship between cognition and either IgG, further research with larger samples is needed to better characterize cognitive differences between AD participants with highversuslow Aβ and RAGE titers. (JINS, 2010,16, 672–678.)