bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viral sequencing to inform the global elimination of dog-mediated rabies - a systematic review
Authors: Jaswant Gurdeep , Bautista Criselda T. , Ogoti Brian , Changalucha Joel , Oyugi Julius O. , Campbell Kathryn , Mutunga Mumbua , Thumbi S.M. , Hampson Katie , Brunker Kirstyn 
Published: May 2024

Background: Rabies is a fatal zoonotic disease, present in almost 150 countries. The “Zero by 30” initiative aims to eliminate human deaths from dog-mediated rabies globally by 2030. This systematic review investigates how viral sequencing can contribute to achieving the “Zero by 30” goal by improving understanding of viral circulation and the impact of rabies control measures.
Methods: A comprehensive search of bibliographic databases was conducted focusing on research on rabies from regions with endemic dog-mediated rabies published between 2000 and 2023, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data were extracted and synthesised to provide recommendations for further research and application to support rabies control.
Results: 220 studies were identified to have documented rabies virus (RABV) sequences from 94 countries, primarily using first-generation technology to produce partial genomes and with sequencing predominantly conducted overseas rather than in-country. Dogs were identified to be the primary RABV reservoir in these regions, although some studies identified more localised wildlife reservoirs. Clade classifications were commonly based on host association or geographical location, however, lack of standardised methods and nomenclature for classifying lineages limited comparison at higher resolution. Cross-species transmission, and both local and long-distance transmission were identified, although quantitative inference was limited. Sequence data was particularly useful for identifying transboundary spread and incursions, investigating host shifts, and tracing sources of human rabies, with endemicity typically characterised by the identification of multiple co-circulating viral lineages.
Conclusion: There is an urgent need for standardised classification methods and phylogeny-based nomenclature for RABVs, and for improved sequencing capacity in regions with endemic dog-mediated rabies, including proficiency in bioinformatics and phylogenetics. Our findings emphasise the critical need to foster international cooperation and coordinate rabies control efforts to reduce transboundary spread, limit reintroductions and maintain progress towards the 2030 target.
La vuelta al mundo en un clic
Authors: Fuentes Luque Adrián , Valdés Rodríguez María Cristina 
Published: May 2024

Lograr la calidad turística implica contar con productos de calidad y, dado que gran parte del contenido turístico se traduce, es necesario realizar traducciones de calidad para garantizar niveles positivos de satisfacción por parte del turista. La diferenciación de una marca se logra a través de la imagen percibida (Andreu et al., 2000, p. 49). En la formación de la imagen intervienen tres componentes: las creencias y actitudes asociadas con el producto, el nivel de conocimiento sobre el destino turístico y las expectativas sobre el producto (Nobs, 2003). Es en estos últimos dos elementos, precisamente, donde la traducción desempeña un papel crucial. Con relativa frecuencia, no se tienen en consideración las expectativas de los usuarios a la hora de diseñar, crear y traducir el material promocional turístico, lo que suele dar lugar a campañas promocionales poco exitosas (e incluso fallidas) que pueden dañar la imagen del destino y de los productos que este ofrece. Dado que la imagen percibida no es un parámetro estático, todos los participantes en el proceso de desarrollo promocional del destino turístico deberían revisar los productos y servicios turísticos implicados, así como la imagen proyectada, tratando de ajustar los nichos de mercado, los productos y destinos a los turistas reales y potenciales, proceso en el que la traducción de los textos de promoción turística desempeña un papel decisivo. En el presente artículo, examinamos la cuestión de la calidad en la traducción del material de promoción turística (ya sea impreso, en páginas web, aplicaciones y redes sociales), ilustrándola a través del análisis de diversas campañas de promoción turística internacional.
OUTCOME ANALYSIS OF BACK MUSCLE STRENGTHENING EXERCISES IN CHRONIC LOW BACKACHE PATIENTS: A RESEARCH PROTOCOL.
Authors: agrawal vineesha , walke rashmi 
Published: May 2024

Abstract

Background : Pain in lower back is a prevalent musculoskeletal issue that affects a huge number of the population at a particular point during their life1. Low back pain is a prevalent problem among elderly, and linked to functional restrictions and disability2. To enhance their athletic abilities as well as the quality of life as a whole, in order to lessen the burden on families, societies, and countries, effective therapy for LBP has been intensively explored3. Physiotherapists recommend electrotherapy, manual therapy, cognitive behavioral treatment and exercise as therapeutic choices for LBP4. LBP is mostly caused by poor posture and organizational ergonomics5. LBP is often treated with conservative management. Physical exercises are extremely important for the treatment of LBP6. Methodology: This exploratory trial will include 60 people with persistent low back pain. Back Strengthening exercises will be performed by the patients. The Visual Analogue Scale will be used to assess pain, and Aberdeen Low Back Pain Scale to assess functional impairment. Discussion: This research is being done to check the effectiveness of lower back muscle strengthening activities in individuals having persistent low back pain.
Droplet-based ISSAAC-seq for multimodal profiling of chromatin accessibility and gene expression in single cells
Authors: Xu Wei , Chen Yawen , Hu Yukun , Chen Xi 
Published: May 2024

Abstract

Here, we described a step-by-step protocol for droplet-based in situ SHERRY after ATAC-seq (ISSAAC-seq), a highly sensitive and flexible single cell multi-omics method to interrogate chromatin accessibility and gene expression from the same single nucleus. ISSAAC-seq is based on the combination of the recently developed Sequencing HEteRo RNA-DNA-hYbrid (SHERRY) and previously established scATAC-seq approaches, and compatible with both plate-based formats and droplet microfluidics. Droplet-based ISSAAC-seq utilizes 10x genomics scATAC platform for single cell isolation, which is suitable for high-throughput cell profiling. Generally, it obtains data quality of ~ 10,000 ATAC reads in peaks and 2000-5000 detected genes per cell. Library construction for ISSAAC-seq could be completed in 1-2 days. This protocol is related to the publication “ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells” in Nature Methods.
Assessing Social Support's Mediating Effects on Rational Antimicrobial Prescribing: A Structural Equation Modeling Study of Healthcare Professionals' Behavior
Authors: Han Le , Liu Xiao , Chang Yue , Liu Ying , Ma Lijun , Ren Jie , Liu Yunshuang , Wang Xiaosong , Long yujuan , zhou yuan , Ren li , Dong baokun 
Published: May 2024

Abstract

Importance: The study addresses the critical issue of antimicrobial resistance, focusing on the role of social support in influencing healthcare professionals' antimicrobial prescribing behavior, a key factor in clinical practice and public health. Objective: The primary objective is to examine the mediating effects of social support on the decision-making processes of healthcare professionals regarding antimicrobial drug use, emphasizing the impact on rational prescribing within a healthcare setting. Evidence Review: The study employed a cross-sectional survey design, analyzing data from 720 healthcare professionals using Structural Equation Modeling. It reviewed how variables such as self-efficacy, knowledge and skills, and health beliefs, informed by theories like RAT, TPB, and HBM, mediate the influence of social support. Findings: The SEM analysis demonstrated significant mediating effects of social support on prescribing intentions through various psychosocial factors. The results offer quantitative insights into the relationships between social support and critical psychological determinants of prescribing behavior. Conclusions and Relevance: The findings elucidate the nuanced impact of social support on antimicrobial prescribing decisions, providing evidence-based insights for enhancing antimicrobial stewardship. This study informs clinicians and policymakers about the significance of social support in promoting rational antimicrobial use.
Atmospheric Retention on Demagnetized Earth
Authors: Hinton Parker , Brain David , Schnepf Neesha , Jarvinen Riku , Cessna Julianna , Bagenal Fran 
Published: May 2024

Abstract

It is commonly claimed that Earth's intrinsic magnetic field protects its atmosphere from being stripped away by the solar wind. We test this claim by analyzing the stability of Earth's atmosphere in the case that the geomagnetic field is turned off. We use a hybrid particle-in-cell code (RHybrid) to simulate the global plasma interaction of demagnetized Earth with the solar wind. We vary the global ionospheric outflow rate, and quantify the resultant planetary ion escape rates (O+ and H+) and the solar deposition rate (H+). We use these results to compute the net mass flux to the atmosphere and find that the solar ion deposition rate can be comparable to planetary ion escape rates. Our results show that under modern solar wind conditions, the mass of the atmosphere on demagnetized Earth is stable within 3% over a billion years, suggesting that Earth's intrinsic magnetic field is unnecessary for atmospheric retention.
Enhanced Multimodal Recommendation Systems through Reviews Integration
Authors: Fang Hong , Liang Jindong , Sha Leiyuxin 
Published: May 2024

Abstract

Multimodal recommendation systems aim to capture diverse user preferences through data such as text and images, offering more personalized recommendation services. Accurately grasping user preferences can enhance the precision of recommendations and augment the user experience. Existing models often exploit the external attributes of item to capture users' preferences while neglecting their intrinsic attributes, such as ease of cleaning and cost-effectiveness, which are revealed in reviews. These attributes often reveal themselves in overlooked reviews. However, directly incorporating reviews into the representation will bring additional noise. Therefore, we propose the Personalized Multi-Preference Recommender (PMPR) model, which integrates reviews with multimodal data to extract multifaceted user preferences, enhancing the personalization of recommendations. Specifically, we designed a heterogeneous graph learning module based on reviews and a homogeneous graph learning module that combines the review features with multimodal features to capture users' diverse preferences. Considering the varying informational content of reviews, PMPR processes each review individually and utilizes user IDs to generate review attention vectors for aggregating the review features to reduce review noise. Finally, we integrate the Top-K method for recommendation. We compare common review processing methods with PMPR's approach to validate its effectiveness. In comparative analyses across three publicly available datasets, our enhanced model consistently demonstrated superior performance when benchmarked against seven widely recognized models. The results indicate a noteworthy improvement over the current State-of-the-Art (SOTA) model, ranging from 2.76\% to 22.52\% in terms of average performance.
M4Net: Towards Occlusion-Robust and Accurate 3D Dense Face Alignment with 3DMM and Mask Augmentation
Authors: ZHAO XIONG , Sulaiman Sarina , LENG WONG YEE 
Published: May 2024

Abstract

Self-occlusion and External-occlusion significantly impact the accuracy of monocular 3D dense face alignment, some approaches based on 3D Morphable Models(3DMM) make much progress on it, although 3DMM is a simple and effective facialprior provider, but it can’t solve the problem of robustness caused by the lack of facial occlusion datasets. In this work, wepresent M4Net (Multi-scale features, Multi-head outputs, Mask Augmentation and based on 3D Morphable Model), a 3D denseface alignment method based on 3DMM with multi-scale features and a novel mask-based augmentation strategy, withoutincreasing training cost but significantly improving the model’s robustness on occlude situations. Moreover, the representationof pose, shape, and expression from the encoder has been decoupled, so we can transfer the target expression to the sourceimage by simply swapping the shape and/or expression represent vector between the target and the source. The quantitativeevaluation results demonstrate that our approach achieves SOTA results on AFLW2000-3D(68pts) and AFLW(21pts), and thequalitative results on three different datasets indicating our method has good occlusion robustness.
Influence of Bonding Temperature on AA2219/Ti-6Al-4V Solid State Diffusion Bonding Joints- Microstructure and Mechanical Characterization
Authors: Vatnalmath Manjunath , Auradi Virupaxi , Murthy Bharath Vedashantha , Nagaral Madeva 
Published: May 2024

Abstract

An attempt has been made to join AA2219 and Ti-6Al-4V by solid state diffusion bonding (SSDB), as this process ensures no macroscopic deformation during the joining. The quality of SSDB joints formed at the bonding temperature in the range of 500-540°C is evaluated using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and x-ray diffraction (XRD). The bonding strength of the joints is evaluated by shear test, and hardness is tested using the Vickers microhardness method. It is observed that the Hardness and shear strength values are increased with an increase in bonding temperature owing to the formation of intermetallic compounds at the joint interface like Al3Ti, Al2Ti and AlTi. Maximum shear strength of 82.48 MPa is observed for the specimen bonded at 540°C.
The psychosocial assessment of candidates for transplantation:a prospective cohort study of its association with mortality among kidney transplant candidates
Authors: Chong Hye Jin , Jang Min Kyeong 
Published: May 2024

Abstract

Background A psychosocial assessment is an important part of the pre-transplant evaluation. Aims To assess the association between scores on the global Psychosocial Assessment of Candidates Transplant tool and survival in deceased donor kidney transplant candidates. Methods In this prospective longitudinal study, the participants were registered candidates on the waiting list for deceased donor kidney transplants at a transplant center in South Korea. Initially, candidates enrolled in this study in 2016 were divided into high- and low-psychosocial risk cohorts using a Psychosocial Assessment of Candidates Transplant score cutoff of 3 points. In 2022, the mortality rate was compared according to whether the initial Psychosocial Assessment of Candidates Transplant score was < 3 or ≥ 3 points. Results This study included 139 deceased donor kidney transplant candidates, of whom 32 (23.0%) received kidney transplantation. An initial Psychosocial Assessment of Candidates Transplant score < 3 was associated with higher mortality 5 years after being placed on the waiting list (hazard ratio = 12.28,p = 0.017). Current alcohol use at baseline was associated with higher mortality 5 years after being placed on the waiting list (hazard ratio = 12.93,p = 0.032). Conclusions Both a high risk of psychosocial candidacy and current alcohol use were associated with significantly reduced survival 5 years after placement on the waiting list for a deceased donor kidney transplant. The psychosocial status of candidates on the waitlist for kidney transplantation should be regularly screened and systematically managed to improve their psychosocial status and reduce alcohol use to make them more suitable candidates for transplant surgery. A psychosocial intervention should be developed for patients on the waiting list to improve their psychosocial status and promote positive health outcomes after kidney transplantation.
Efficacy of Aloe vera toothpaste during active periodontal treatment: A clinical study
Authors: Vajrabhaya La-ongthong , Benjasupattananan Supranee , Sappayatosok Kraisorn , Dechosilpa Vittawin , Korsuwannawong Suwanna , Sirikururat Papatpong 
Published: May 2024

Abstract

Background
While professional dental treatments are mandatory for advance periodontitis, maintaining proper oral hygiene can significantly contribute to preventing disease progression. Some herbal toothpastes and natural plant components may have some beneficial properties. Aloe vera is a medicinal plant with active ingredients that show antioxidant and anti-inflammatory effects. A toothpaste containing salt and Aloe vera may have adjunctive influence to non-surgical periodontal treatment.
Aim
This randomized parallel-group comparison study aimed to investigate the efficacy of an Aloe vera toothpaste (test group) compared to a Sodium bicarbonate toothpaste (control group) and a base toothpaste (benchmark group), with respect to outcomes of periodontitis treatment.
Methods
Fifty-four periodontitis patients were arbitrarily allotted into three groups. All subjects received mechanical instrumentation and instruction on oral hygiene using a toothbrush with these toothpastes and dental floss for a whole period of the study. The participants were evaluated at baseline (T0), week 4 (T1), and week 12 (T2) after complete full mouth scaling and root planing. During the visits, plaque score (PS), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were assessed and analyzed.
Results
The comparison groups had similar mean PS and BOP at baseline. At T1 and T2, both scores were reduced, however there was no statistically significant difference among the three groups for PS. A significant reduction in BOP score among the groups was observed (p < 0.01) at T1. The PD in all groups were reduced significantly after non-surgical periodontal treatment. The CAL reduction was superior in the test group compared to the benchmark and the control group. In addition, there was no significant difference in the mean CAL among time points in the both benchmark and control groups.
Conclusions
Aloe vera toothpaste significantly decreased gingival bleeding, probing depth, and clinical attachment level in periodontitis patients during active periodontal treatment.
Causes of Pre and Post-Donation Deferrals among Blood Donors, at Kwale Satellite Blood Transfusion Center, Kwale County, Kenya, 2018-2022.
Authors: Nyamu Gibson Waweru , Shee Matano Ali , Kiende Polly , Muthiani Benson Muithya , Nakazea Rocky Jumapili , Mwasowa Narcis Mwakidedela , Odhiambo Frendrick Odhiambo , King'oo Jacintah Mueni , Wigina Ronald Nyarambe 
Published: May 2024

Abstract

Background: Both pre-donation and post-donation deferrals pose challenges to blood safety and availability. This study delved into the deferral rates before donations and their underlying reasons, also, transfusion transmissible infections (TTIs) leading to post-donation deferrals among potential blood donors at the Kwale satellite Blood Transfusion Centre (KSBTC) in Kenya.
Methods: We performed a retrospective electronic record review of both pre and post donations deferrals among blood donors at KSBTC, 2018-2022. The pre-donations deferral rate and reasons for deferral were analyzed. Accepted donations were analyzed to determine the prevalence of HIV, hepatitis B (HBV), hepatitis C (HCV), and syphilis. Descriptive statistics were calculated and both crude odds ratio (COR) and adjusted odds ratio (AOR), and their 95% confidence intervals (CI) were calculated. Variables with p < 0.05 were considered statistically significant.
Results: A review was conducted on 12,633 blood donation records. Among these, individuals 2,729/12,633 (21.60%) were deferred from donating with the primary reason being low hemoglobin levels, constituting 51.86% of deferrals.
Around 773/9,904 (7.80%) of blood units, were discarded due to at least one TTI. Among these, HBV accounted for 4.73%, HIV for 2.01%, HCV for 1.21%, and Syphilis for 0.59% of cases. The adjusted odds ratio for male donors were, (aOR =1.3, 95% CI 1.01-1.57), donors with none or primary education level (aOR =1.4 95% CI 1.11-1.68), first timer donors (aOR=1.2, 95% CI 1.01-1.44), and static strategy for blood collection (aOR =1.4, 95%CI 1.12-1.63) were independently potentially associated with testing positive for at least one TTI.
Conclusion: The study indicates that TTIs continue to pose a risk to the safety of Kenya's blood stock, with a notable prevalence of HBV infections. Male donors, individuals with limited education, first-time donors, and the utilization of a fixed strategy for blood collection were identified as potential risk factors independently associated with TTIs.
Retrospective analysis of 5-year survivorship of Dual Mobility Total Hip Arthroplasty
Authors: chauhan sanjay singh , solanki ankit , desai mohan , jose ankit 
Published: May 2024

Abstract

Background
The concept of Dual Mobility (DM) Total Hip Arthroplasty (THA) has been introduced to improve the range of motion in the post-operative hips. However, literature on the mid-term and long-term outcomes of DM-THA are relatively lacking.
Question / Purpose
What are the mid-term results (minimum 5 years post-operatively) of DM THA surgeries done for various indications?
Patients and Methods
We recruited sixty participants over a period of one year who underwent DM THA surgeries. The clinical outcomes were evaluated using the Harris’ Hip Score (HHS) and the Oxford Hip Score (OHS). The participant subjective assessment of the post-operative condition was classified into excellent, good, and fair. Adverse events were recorded. The radiological outcomes were evaluated using the Moore’s criteria of osteointegration (MCO). The scores were determined for the various age groups and participant perceptions, and compared using the one-way Analysis of Variance (ANOVA).
Results
The mean age of our participants was 65.77 ± 10.13 years. Thirty-six participants reported excellent subjective post-operative outcomes. The mean values for HHS, OHS, and MCO were found to be 87.38 ± 4.41, 37.35 ± 4.60, and 3.10 ± 0.47 respectively. The HHS, OHS, and MCO were significantly better in participants who subjectively reported excellent outcomes (p < 0.001 each). The MCO was also significantly lesser with increasing age (p = 0.020). Two of our study participants experienced persistent thigh pain, while heterotrophic calcification, aseptic loosening of the hip joint prosthesis, and revision THR (at six years post-operatively) were observed in one participant each.
Conclusion
We observed reasonably good clinical and radiological outcomes in our study, with most of the study participants reporting their post-operative condition to be excellent. The HHS, OHS, and MCO correlated with the participant’s subjective perceptions. The overall incidence of complications was found to be low in our study.
Level of evidence
Level II