bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural Flexibility and Sorption Properties of 2D Porous Coordination Polymers Constructed from Trinuclear Heterometallic Pivalates and 4,4′‐Bipyridine
Authors: Polunin Ruslan A. , Kolotilov Sergey V. , Kiskin Mikhail A. , Cador Olivier , Golhen Stéphane , Shvets Oleksiy V. , Ouahab Lahcène , Dobrokhotova Zhanna V. , Ovcharenko Victor I. , Eremenko Igor L. , Novotortsev Vladimir M. , Pavlishchuk Vitaly V. 
Published: September 2011

AbstractThe temperature dependence of crystal structure parameters of isostructural coordination polymers Fe2MO(Piv)6(bipy)1.5·2DMF [1·2DMF and 2·2DMF, where M = NiII or CoII, respectively, Piv = (CH3)3CCO2–, bipy = 4,4‐bipyridine and DMF is N,N‐dimethylformamide] was studied at five temperatures in the range from 120 to 296 K. The X‐ray structure of the N,N‐diethylformamide (DEF) solvate of the same coordination polymer 1, Fe2NiO(Piv)6(bipy)1.5·2DEF (1·2DEF), was studied at 173 and 260 K. Both the DMF and DEF solvates possess similar crystal structures, consisting of a series of parallel 2D polymeric layers with honeycomb voids. These series of parallel layers intersect, leading to their interpenetration and formation of zig‐zag channels. It was found that the change of temperature and/or solvent molecule in the pores causes significant structural rearrangement associated with a change of the separation between parallel layers and the angle between intersecting layers. These structural changes lead to a variation of the calculated solvent‐accessible volume from 0.21 cm3 g–1 (120 K, 2·2DMF) to 0.30 cm3 g–1 (260 K, 1·2DEF) for a probe molecule with r = 1.4 Å. These changes can model structural transformations which can occur at desolvation and adsorption of guests. Adsorption of n‐hexane, n‐octane, methanol and ethanol by Fe2MO(Piv)6(bipy)1.5 was studied. The sorption isotherms of alkanes were typical for microporous sorbents and in this case the behaviour of the coordination polymers resembled that which is typical for sorbents with a rigid structure. In a contrast, alcohol sorption capacity continuously grew at increasing pressure which may be caused by structural transformations, similar to temperature‐induced structural transformations. Among the studied sorbates, sorption capacity grew in order methanol < ethanol < n‐hexane < n‐octane which may be caused by the hydrophobic nature of the channels (due to the presence of tert‐butyl groups).
Photocatalytic H2 and Added‐Value By‐Products – The Role of Metal Oxide Systems in Their Synthesis from Oxygenates (Eur. J. Inorg. Chem. 28/2011)
Authors: Cargnello Matteo , Gasparotto Alberto , Gombac Valentina , Montini Tiziano , Barreca Davide , Fornasiero Paolo 
Published: September 2011

AbstractThe cover picture shows how light can be efficiently used to activate hydrogen production over metal oxides from biomass‐derived compounds, such as alcohols and sugars. These processes have gained a considerable importance for the sustainable production of H2, a strategic energy vector, starting from renewable resources. Interestingly, H2 generation from these largely available raw materials is accompanied by the simultaneous formation of added‐value by‐products that might be appealing even for other applications. The Microreview by D. Barreca, P. Fornasiero et al. on p. 4309 ff. focuses on recent developments in the field, discussing selected representative research results and highlighting the major open problems and future perspectives.
Peterson Olefination: Unexpected Rearrangement in the Overcrowded Polycyclic Aromatic Ene Series
Authors: Assadi Naela , Pogodin Sergey , Agranat Israel 
Published: September 2011

AbstractAn attempted synthesis of the angularly annelated 9‐(11′‐benzo[a]fluoren‐11′‐ylidene)‐9H‐fluorene (3) through a Peterson olefination reaction between (9H‐fluoren‐9‐yl)trimethylsilyl anion (5a) and 11H‐benzo[a]fluoren‐11‐one (6) led to the linearly annelated 9‐(11′‐benzo[b]fluoren‐11′‐ylidene)‐9H‐fluorene (4), due to an unexpected rearrangement. The proposed mechanism of the rearrangement is illustrated. The core of the mechanism is an intramolecular Haller–Bauer cleavage of the naphthyl C11a′–C11′ bond in the β‐oxysilane anion 11 (formed from 5a and 6) to give the 1‐naphthyl anion (E)‐12, followed by E/Z isomerization to (Z)‐12 and by proton migration to give the 3‐naphthyl anion (Z)‐14. The intramolecular nucleophilic addition of the naphthyl anion at C‐3′ of (Z)‐14 to the carbonyl carbon gives the β‐oxysilane anion 15, a benzo[b]fluorenylidene derivative. The mechanism is supported by the results of DFT calculations. The synthesis of 3 was achieved by application of Barton's double extrusion diazo–thione coupling method.
Preparation of an Electrode Modified with an Electropolymerized Film as a Mediator of NADH Oxidation and Its Application in an Ethanol/O2 Biofuel Cell
Authors: Masuda Miyuki , Motoyama Yusuke , Murata Kenichi , Nakamura Nobuhumi , Ohno Hiroyuki 
Published: September 2011

AbstractThis paper reports a novel mediator for the oxidation of β‐nicotinamide adenine dinucleotide (NAD+/NADH), an electropolymeric film (pAPRu) of [Ru(NH2‐phen)3]2+. A pAPRu‐modified electrode was prepared via electropolymerization and exhibited catalytic activity toward the electrochemical oxidation of NADH due to the imine moieties of pAPRu. The electrochemical oxidation of ethanol was observed using an alcohol dehydrogenase (ADH)‐immobilized electrode. A compartmentless ethanol/O2 biofuel cell composed of an ADH anode and a bilirubin oxidase cathode was constructed. The maximum current density and the maximum power density of the biofuel cell were 190 µA cm−2 and 31 µW cm−2 (at 0.29 V), respectively.
Out‐of‐plane seismic behaviour of rocking masonry walls
Authors: Shawa Omar Al , de Felice Gianmarco , Mauro Alberto , Sorrentino Luigi 
Published: September 2011

SUMMARYThe evaluation of the out‐of‐plane behaviour of unreinforced walls is one of the most debated topics in the seismic assessment of existing masonry buildings. The discontinuous nature of masonry and its interaction with the remainder of the building make the dynamic modelling of out‐of‐plane response troublesome. In this paper, the results of a shaking table laboratory campaign on a tuff masonry, natural scale, U‐shaped assemblage (façade adjacent to transverse walls) are presented. The tests, excited by scaled natural accelerograms, replicate the behaviour of external walls in existing masonry buildings, from the beginning of rocking motion to overturning. Two approaches have been developed for modelling the out‐of‐plane seismic behaviour: the discrete element method and an SDOF analytic model. Both approaches are shown to be capable of reproducing the experimental behaviour in terms of maximum rotation and time history dynamic response. Finally, test results and numerical time history simulations have been compared with the Italian seismic code assessment procedures. Copyright © 2011 John Wiley & Sons, Ltd.
Validity and Reliability of a Turkish Version of the Body Shape Questionnaire Among Female High School Students: Preliminary Examination
Authors: Akdemir Asena , Inandi Tacettin , Akbas Duygu , Karaoglan Kahilogullari Akfer , Eren Mehmet , Canpolat Banu Isik 
Published: September 2011

AbstractThe aim of this study is to assess the validity and reliability of a Turkish version of the Body Shape Questionnaire (BSQ) among young people. The BSQ was initially administrated to female high school students (N = 665) and administered a second time to a subset of subjects (N = 144). The subjects also completed the Eating Attitudes Test, the Body Image Satisfaction Questionnaire (a dieting questionnaire) and the Hopkins Symptom Checklist (SCL‐90), and were weighed, and their body mass indices were calculated. Test–retest reliability of the BSQ was 0.81. The BSQ score correlated highly with the Eating Attitudes Test, Body Image Satisfaction Questionnaire and the Hopkins Symptom Checklist. Higher BSQ scores were also associated with higher body mass index. The results suggest that the Turkish version of BSQ is a valid and reliable tool for assessing body image concerns in teenagers. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
Modeling metal bioaccumulation in the invasive mussels Dreissena polymorpha and Dreissena rostriformis bugensis in the rivers Rhine and Meuse
Authors: Le T.T. Yen , Leuven Rob S.E.W , Hendriks A. Jan 
Published: September 2011

Abstract
The metal-specific covalent index and the species-specific size-based filtration rate were integrated into a biokinetic model estimating metal bioaccumulation in mussels from the dissolved phase and phytoplankton. The model was validated for zebra (Dreissena polymorpha) and quagga (Dreissena rostriformis bugensis) mussels in the rivers Rhine and Meuse, the Netherlands. The model performed well in predicting tissue concentrations in different-sized zebra mussels from various sampling sites for 55Mn, 56Fe, 59Co, 60Ni, 82Se, 111Cd, 118Sn, and 208Pb (r2 = 0.71–0.99). Performance for 52Cr, 63Cu, 66Zn, 68Zn, and 112Cd was moderate (r2 &lt; 0.20). In quagga mussels, approximately 73 to 94% of the variability in concentrations of 82Se, 111Cd, 112Cd, and 208Pb was explained by the model (r2 = 0.73–0.94), followed by 52Cr, 55Mn, 56Fe, 60Ni, and 63Cu (r2 = 0.48–0.61). Additionally, in both zebra and quagga mussels, average modeled concentrations were within approximately one order of magnitude of the measured values. In particular, in zebra mussels, estimations of 60Ni and 82Se concentrations were equal to 51 and 76% of the measurements, respectively. Higher deviations were observed for 52Cr, 59Co, 55Mn, 56Fe, 111Cd, 63Cu, and 112Cd (underestimation), and 66Zn, 68Zn, 208Pb, and 118Sn (overestimation). For quagga mussels, modeled concentrations of 66Zn and 68Zn differed approximately 14% from the measured levels. Differences between predictions and measurements were higher for other metals. Environ. Toxicol. Chem. 2011;30:2825–2830. © 2011 SETAC
Thermal properties and microstructure of gypsum board and its dehydration products: A theoretical and experimental investigation
Authors: Yu Q. L. , Brouwers H. J. H. 
Published: September 2011

SUMMARYThis article addresses the thermal properties and the microstructure of gypsum boards produced from β‐hemihydrate by studying its dehydration process.Dehydration reaction of gypsum boards was investigated from both micro and macro levels, employing thermogravimetric analysis and a ventilated oven. A new dehydration mechanism of gypsum was proposed. The thermal properties of gypsum board such as enthalpy of reaction, specific heat capacity, and thermal conductivity were studied by differential scanning calorimetry and a heat transfer analyzer, respectively. The effect of void fraction and dehydration on thermal physical properties of gypsum board was investigated. The microstructure of the gypsum board at high temperature was studied with experiments and modeling. A model was proposed to describe the microstructure of a dehydrated system at high temperature, and experiments indicate its validity. Furthermore, the mechanical properties of gypsum at high temperature were investigated, and the effect of water content was discussed as well. Copyright © 2011 John Wiley & Sons, Ltd.
Composition and architecture of biofilms on used voice prostheses
Authors: Buijssen Kevin J. D. A. , van der Laan Bernard F. A. M. , van der Mei Henny C. , Atema–Smit Jelly , van den Huijssen Pauline , Busscher Henk J. , Harmsen Hermie J. M. 
Published: September 2011

AbstractBackgroundBiofilms on medical devices are a frequent reason for failure of the device. Voice prostheses in laryngectomized patients deteriorate within 3 to 4 months due to adhering biofilms, impeding proper functioning. Recently, we showed that these biofilms are dominated by Candida and lactobacilli. However, the early report of this finding lacked an indepth analysis of the species diversity and community structure.MethodsDenaturing gradient gel electrophoresis (DGGE) and sequence analysis of amplified rRNA genes was used to identify microorganisms. Fluorescence in situ hybridization (FISH) was used to analyze biofilm architecture.ResultsCandida are the predominant fungi in the biofilms, while lactobacilli are the predominant bacteria in all investigated biofilms, followed by streptococci. FISH shows that lactobacilli and streptococci seem to have an important interaction with fungi.ConclusionThe results give a better understanding of biofilm formation and can be used in further development to prevent biofilm formation on voice prostheses. © 2011 Wiley Periodicals, Inc. Head Neck, 2011
Acute glucocorticoid effects on the multicomponent model of working memory
Authors: Vaz Leonardo José , Pradella‐Hallinan Márcia , Bueno Orlando Francisco Amodeo , Pompéia Sabine 
Published: September 2011

ObjectiveIn comparison with basal physiological levels, acute, high levels of cortisol affect learning and memory. Despite reports of cortisol‐induced episodic memory effects, no study has used a comprehensive battery of tests to evaluate glucocorticoid effects on the multicomponent model of working memory. Here, we report the results of a double‐blind, placebo‐controlled, between‐subjects study.MethodsTwenty healthy young men were randomly assigned to either acute cortisol (30 mg hydrocortisone) or placebo administration. Participants were subjected to an extensive cognitive test battery that evaluated all systems of the multicomponent model of working memory, including various executive domains (shifting, updating, inhibition, planning and access to long‐term memory).ResultsCompared with placebo, hydrocortisone administration increased cortisol blood levels and impaired working memory in storage of multimodal information in the episodic buffer and maintenance/reverberation of information in the phonological loop. Hydrocortisone also decreased performance in planning and inhibition tasks, the latter having been explained by changes in storage of information in working memory.ConclusionsThus, hydrocortisone acutely impairs various components of working memory, including executive functioning. This effect must be considered when administering similar drugs, which are widely used for the treatment of many clinical disorders. Copyright © 2011 John Wiley & Sons, Ltd.
Dickkopf1: A tumor suppressor or metastasis promoter?
Authors: Menezes Mitchell E. , Devine Daniel J. , Shevde Lalita A. , Samant Rajeev S. 
Published: September 2011

AbstractDickkopf1 (DKK1), a secreted inhibitor of the Wnt/β‐catenin pathway, is a negative regulator of bone formation. DKK1 acts as a switch that transitions prostate cancer bone metastases from osteolytic to osteoblastic and also is an active indicator of poor outcome for multiple myeloma. However, in other tumor types, DKK1 upregulation or overexpression suppresses tumor growth. Thus, the role of DKK1 in cancer appears to be diverse. This raises a question: Could the increased levels of DKK1 still be tumor protective when observed in high levels in the serum of patients? Here, we summarize the diverse, seemingly contradicting roles of DKK1 and attempt to explain the apparent dichotomy in its activity. We propose that DKK1 is a critical secreted factor that modulates microenvironment. Based on the location and components of the microenvironment DKK1 will support different outcomes.
HLA‐E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression
Authors: Bossard Céline , Bézieau Stéphane , Matysiak‐Budnik Tamara , Volteau Christelle , Laboisse Christian L. , Jotereau Francine , Mosnier Jean‐François 
Published: September 2011

AbstractThe host immune response plays a major role in colorectal carcinoma (CRC) progression. A mechanism of tumor immune escape might involve expression of the human leucocyte antigen (HLA)‐E/β2m on tumor cells. The inhibitory effect of HLA‐E/β2m on CD8+ cytotoxic T lymphocytes and natural killer (NK) cells is mediated by the main HLA‐E receptor CD94/NKG2A. As the pathophysiological relevance of this mechanism in CRC remains unknown, this prompted us to examine, in situ, in a series of 80 CRC (i) the HLA‐E and β2m coexpression by tumor cells, (ii) the density of CD8+, cytotoxic, CD244+ and NKP46+ intraepithelial tumor‐infiltrating lymphocyte (IEL‐TIL) and (iii) the expression of CD94/NKG2 receptor on IEL‐TIL. These data were then correlated to patient survival. We provided (i) the in situ demonstration of HLA‐E/β2m overexpression by tumor cells in 21% of CRC characterized by an overrepresentation of signet ring cell carcinomas, mucinous carcinomas and medullary carcinomas, (ii) the significant association between HLA‐E/β2m overexpression by tumor cells and increased density of CD8+ cytotoxic, CD244+ and CD94+ IEL‐TIL and (iii) finally, the unfavorable prognosis associated with HLA‐E/β2m overexpression by tumor cells. Our findings show that HLA‐E/β2m overexpression is a surrogate marker of poor prognosis and point to a novel mechanism of tumor immune escape in CRC in restraining inhibitory IEL‐TIL.
Cellular Uptake, Intracellular Trafficking and Biological Responses of Gold Nanoparticles
Authors: Jiang Xiu‐Mei , Wang Li‐Ming , Chen Chun‐Ying 
Published: September 2011

AbstractPromising application of gold nanoparticles (GNPs) in biomedical and environmental fields is increasing the likelihood of direct interaction with living systems. The knowledge about GNPs interacting with cells is quite limited and however, is necessary for risk prediction and evaluation of biological effects. Herein, we review recent advances in cellular effects of GNPs including cellular uptake, trafficking, subcellular distribution and cellular responses, and the relationship between physiochemical properties of GNPs and biological effects as well. To uncover these issues, it is quite instructive for safe and sustainable use of GNPs.
Comparison of ultrasonographically guided fine‐needle aspiration and core needle biopsy in the diagnosis of parotid masses
Authors: Huang Yu‐Chieh , Wu Chen‐Te , Lin Gigin , Chuang Wen‐Yu , Yeow Kee‐Min , Wan Yung‐Liang 
Published: September 2011

AbstractBackground.To retrospectively compare the accuracies of ultrasound‐guided fine‐needle aspiration (USFNA) and ultrasound‐guided core needle biopsy (USCNB) in the diagnosis of parotid masses.Methods.A total of 171 patients (aged 17–86 years, mean 54 years) with parotid masses (35 malignant and 136 benign lesions) underwent either USFNA (n = 107) or USCNB (n = 64). The diagnostic accuracies for differentiating benign from malignant lesions of both examinations were compared. Surgical histopathology (n = 104) and clinical diagnosis (n = 67) were used to establish the final diagnoses.Results.USCNB had a significantly higher sensitivity (94.1%) than USFNA (55.6%) (p < 0.05) in differentiating benign lesions from malignant conditions. The specificity and overall accuracy of USCNB were higher than those of USFNA (100% and 98.4% versus 93.3% and 86.9%, respectively). USCNB provided more specific diagnosis than USFNA (100% versus 93.3%, p < 0.05). All six patients with lymphomas who underwent USCNB were accurately diagnosed, whereas all four patients with lymphomas who underwent USFNA were not.Conclusions.USCNB should be preferred to USFNA when a definite diagnosis of a parotid solid mass is needed. © 2011 Wiley Periodicals, Inc. J Clin Ultrasound, 2011;
Gene delivery methods in cardiac gene therapy
Authors: Ishikawa Kiyotake , Tilemann Lisa , Fish Kenneth , Hajjar Roger J. 
Published: September 2011

AbstractGene therapy for the treatment of heart failure is emerging as a multidisciplinary field demonstrating advances with respect to identifying key signaling pathways, modernized vector creation and delivery technologies. Although these discoveries offer significant progress, selecting optimal methods for the vector delivery remains a key component for efficient cardiac gene therapy to validate the targets in rodent models and to test clinically relevant ones in pre‐clinical models. Although the goals of higher transduction efficiency and cardiac specificity can be achieved with several delivery methods, the invasiveness and patient safety remain unclear for clinical application. In this review, we discuss various features of the currently available vector delivery methods for cardiac gene therapy. Copyright © 2011 John Wiley & Sons, Ltd.
Model‐specific selection of molecular targets for heart failure gene therapy
Authors: Katz Michael G. , Fargnoli Anthony S. , Tomasulo Catherine E. , Pritchette Louella A. , Bridges Charles R. 
Published: September 2011

AbstractHeart failure (HF) is a complex multifaceted problem of abnormal ventricular function and structure. In recent years, new information has been accumulated allowing for a more detailed understanding of the cellular and molecular alterations that are the underpinnings of diverse causes of HF, including myocardial ischemia, pressure‐overload, volume‐overload or intrinsic cardiomyopathy. Modern pharmacological approaches to treat HF have had a significant impact on the course of the disease, although they do not reverse the underlying pathological state of the heart. Therefore gene‐based therapy holds a great potential as a targeted treatment for cardiovascular diseases. Here, we survey the relative therapeutic efficacy of genetic modulation of β‐adrenergic receptor signaling, Ca2+ handling proteins and angiogenesis in the most common extrinsic models of HF. Copyright © 2011 John Wiley & Sons, Ltd.
Cluster Analysis Examination of Serial Killer Profiling Categories: A Bottom‐Up Approach
Authors: Taylor Sandie , Lambeth Daniel , Green Georga , Bone Rachael , Cahillane Marie A. 
Published: September 2011

AbstractTwo studies explored the validity of dichotomous classification of organised/disorganised serial killers and the four typologies (visionary, mission, hedonistic, and power/control) adopted by the Federal Bureau of Investigation (FBI). Tables documenting crime scene criteria were devised consisting of 50 typifying different crime scenes (Study 1) and 48 crime scenes (taken from the 50 crime scene criteria) with a further 10 motive‐based crime scene criteria (Study 2). Adopting content analysis, crime scenes depicted for 40 (Study 1) and 40 (Study 2) serial killers using secondary sources of data were dichotomously coded for the presence or absence of the crime scene criteria. These data were inputted for agglomerative hierarchical cluster using Ward's method as the clustering algorithm. Differences in the nature of clusters were found for male and female serial killers; however, there was no empirical support for the organised/disorganised classifications or the four typologies. The ‘bottom‐up’ approach resulted in clusters from the different crime scene criteria that helped to understand how these criteria were associated within the serial killer cohort considered. It is concluded that the resulting clusters in both studies support the notion of there being an underlying organised element to most serial murder and that serial murders differ according to the nature of disorganised crime scene criteria present. Copyright © 2011 John Wiley & Sons, Ltd.