bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of barriers and motivators on intention and confidence to undergo hereditary cancer genetic testing
Authors: Austin Sarah , Hanson Erika N. , Delacroix Emerson , Bacon Elizabeth , Rice John , Gerido Lynette Hammond , Rizzo Elizabeth , Pleasant Versha , Stoffel Elena M. , Griggs Jennifer J. , Resnicow Ken 
Published: May 2024

AbstractGenetic testing for hereditary cancer syndromes can provide lifesaving information allowing for individualized cancer screening, prevention, and treatment. However, the determinants, both barriers and motivators, of genetic testing intention are not well described. A survey of barriers and motivators to genetic testing was emailed to adult patients eligible for genetic testing based on cancer diagnosis who previously have not had genetic testing (n = 201). Associations between barriers/motivators with testing intention and confidence were examined first by correlation followed by multivariable linear regression model holding constant potential covariates. Seven barrier items from two domains (logistics and genetic testing knowledge) were found to significantly negatively correlate with genetic testing intention. Unexpectedly, three barrier items had significant positive correlation with genetic testing intention; these were related to family worry (passing a condition on to future generations) and testing knowledge (needing more information on the genetic testing process and what it has to offer). Ten barrier items had significant negative correlation with confidence to get a genetic test and encompassed four domains: stigma, insurance/genetic discrimination, knowledge, and cost. All motivator items were associated with intention to get a genetic test, while none were associated with confidence. Multivariable analysis yielded six total barriers (five from the knowledge domain, one from cost domain) and two motivators (relieved to know and treatment impact) that were significantly associated with genetic testing intention or confidence when controlling for demographic characteristics. These findings indicate the need for tailored interventions to amplify motivating factors and counter‐message barriers to enhance patient motivation and confidence to undergo testing.
Effect of IWATE laparoscopic difficulty score on postoperative outcomes and costs for robotic hepatectomy: Are complex resections more expensive?
Authors: Sucandy Iswanto , Vasanthakumar Prakash , Ross Sharona B. , Pattilachan Tara M. , Christodoulou Maria , App Samantha , Rosemurgy Alexander 
Published: May 2024

AbstractBackgroundThe IWATE criteria, a four‐level classification system for laparoscopic hepatectomy, measures technical complexity but lacks studies on its impact on outcomes and costs, especially in robotic surgeries. This study evaluated the effects of technical complexity on perioperative outcomes and costs in robotic hepatectomy.MethodsSince 2013, we prospectively followed 500 patients who underwent robotic hepatectomy. Patients were classified into four levels of IWATE scores; (low [0–3], intermediate [4–6], advanced [7–9], and expert [10–12]) determined by tumor characteristics, liver function and resection extent. Perioperative variables were analyzed with significance accepted at a p‐value ≤.05.ResultsAmong 500 patients, 337 (67%) underwent advanced to expert‐level operations. Median operative duration was 213 min (range: 16–817 min; mean ± SD: 240 ± 116.1 min; p < .001) and estimated blood loss (EBL) was 95 mL (range: 0–3500 mL; mean ± SD:142 ± 171.1 mL; p < .001). Both operative duration and EBL showed positive correlations with increasing IWATE scores. Median length of stay (LOS) of 3 days (range: 0–34; mean ± SD:4 ± 3.0 days; p < .001) significantly correlated with IWATE score. Total cost of $25 388 (range: $84–354 407; mean ± SD: 29752 ± 20106.8; p < .001) also significantly correlated with operative complexity, however hospital reimbursement did not. No correlation was found between IWATE score and postoperative complications or mortality.ConclusionsClinical variables such as operative duration, EBL, and LOS correlate with IWATE difficulty scores in robotic hepatectomy. Financial metrics such as costs but not reimbursement received by the hospital correlate with IWATE scores.
Locking in overseas buyers amid geopolitical conflicts
Authors: Fan Di , Ma Pengcheng , Cui Lin , Yiu Daphne W. 
Published: May 2024

AbstractGeopolitical conflicts, particularly economic ones, introduce significant uncertainties into the global supply chain. The impact of these conflicts on cross‐border buyer–supplier transactions remains underexplored, as does the capability of global suppliers to mitigate such risks by locking in their foreign buyers. Employing a combined perspective of resource dependence theory and transaction cost economics, we examine a natural experiment to investigate the effects of the 2018 U.S.–China trade war on the transactional relationships between Chinese suppliers and their U.S. buyers. Our study reveals that the trade war generally adversely affected these buyer–supplier transactional relationships, leading to a negative abnormal transaction value in the affected dyads, which amounted to 18.42% of their pre‐event level. However, we find that this adverse impact can be attenuated when Chinese suppliers demonstrate superior innovation capabilities, higher corporate social responsibility performance, or fewer local political ties. These findings yield insights for international suppliers and buyers on strategies to maintain buyer–supplier transactions and minimize the detrimental effects on global supply chain relationships during geopolitical conflicts.
Celiac disease in North America: What is the current practice of pediatric gastroenterology providers?
Authors: Singh Arunjot , Silvester Jocelyn , Turner Justine , Absah Imad , Sparks Brandon A. , Walsh Catharine M. , Bracken Julia M. , Stanisz Joanna , Hajjat Temara , Badalyan Vahe , Chugh Ankur , Hoffenberg Edward J. , Dowhaniuk Jenna K. 
Published: May 2024

AbstractObjectivesWhile guidelines exist for the diagnosis and management of pediatric celiac disease (CeD), current practices in North America are not well‐described. This study aimed to explore current practice patterns to identify gaps and direct future clinical, training and research initiatives.MethodsA 23‐item survey designed by the Celiac Disease Special Interest Group was distributed electronically to its members. Questions explored four themes: (1) screening and diagnosis pre and post the coronavirus disease (COVID)‐19 pandemic, (2) treatment and monitoring, (3) family screening and transition of care, and (4) CeD focused training.ResultsThe survey response rate was 10.8% (278/2552). Most respondents were from the United States (89.9%, n = 250) and Canada (8.6%, n = 24). While endoscopy remained the gold standard, serology‐based diagnosis was accepted by 47.5% (132/278). In response to the COVID‐19 pandemic, 37.4% of providers changed their diagnostic practice. Barriers to care included: lack of insurance coverage for dietitians, wait times, and lack of CeD focused training. During fellowship 69.1% (192/278) reported no focused CeD training.ConclusionSurvey results revealed practice variation regarding the diagnosis and management of CeD in North America including a substantial proportion accepting non‐biopsy, serology‐based diagnosis, which increased during the COVID‐19 pandemic. Variations in screening, diagnosis, interval surveillance, and family screening were also identified. Dedicated CeD education in pediatric gastroenterology fellowship may be an opportunity for standardizing practice and advancing research. Future North American guidelines should take current care patterns into consideration and develop new initiatives to improve care of children with CeD.
Wound vacuum‐assisted closure temporization after tumor resection of soft tissue sarcomas—A cost analysis in a propensity‐score matched population
Authors: Gonzalez Marcos R. , de Groot Tom M. , Werenski Joseph O. , Fourman Mitchell S. , Morse Ashlyn S. , Lozano‐Calderon Santiago A. 
Published: May 2024

AbstractBackgroundVacuum‐assisted closure (VAC) temporization is a technique associated with high local control rates used in myxofibrosarcoma. We sought to compare the costs and postoperative outcomes of VAC temporization and single‐stage (SS) excision/reconstruction.MethodsWe conducted a retrospective analysis of patients with myxofibrosarcoma surgically treated at our institution between 2000 and 2022. Variables of interest included total, direct, and indirect costs for initial episode of care, 90 days and 1 year after initial admission, and postoperative outcomes. Costs were compared between the VAC temporization and SS groups.ResultsAfter matching, 13 patients in the SS group and 23 in the VAC group were analyzed. We found no difference in median and mean total inpatient costs, between the VAC temporization and SS group. While total 90‐day and 1‐year costs were higher in the VAC group compared to the SS group, mean costs were similar. There were no differences in postoperative complications between groups. A subanalysis of the entire cohort (n = 139) revealed lower local recurrence and overall death rates in the VAC temporization group.ConclusionVAC temporization had similar inpatient costs and postoperative outcomes to SS excision/reconstruction. While median 90‐day and 1‐year costs were higher in the VAC group, mean costs did not differ.
A dermocosmetic regimen is effective and safe for mild to moderate acne in subjects of all skin phototypes
Authors: Flament Frédéric , Imko‐Walczuk Beata , Aslham Doarika Abdool , Prestat‐Marquis Elodie , Biassin Romain , Nioré Margot , Canchy Ludivine , Tan Jerry 
Published: May 2024

AbstractBackgroundAcne vulgaris is a chronic inflammatory skin condition with a multifactorial pathogenesis. The clinical appearance of acne and its sequelae may differ according to phototypes. Data regarding the potential benefit of dermocosmetics (DC) regardless of phototype are lacking and assessing acne improvement can be difficult, given the lack of visual support in people with skin of colour. A DC regimen, combining a cleanser and a cream, both containing thermal spring water, has been developed for the management of mild‐to‐moderate acne, for all skin phototypes studied.ObjectivesTo assess the efficacy and local tolerance of a DC routine in mild‐to‐moderate acne and to visualize the clinical improvement in all skin phototypes.MethodsIn an open‐labelled, multicentre clinical study, subjects of any phototype aged above 11 years and above with mild (N = 48, 55.2%) or moderate (N = 39, 44.8%) facial acne applied the DC twice daily for 56 days. No other acne care was allowed. Acne severity, as well as inflammatory and noninflammatory lesion counts, were assessed at baseline, Days 28 and 56. Photographs were taken using a novel imaging tool based on multimodal acquisition, to show clinical improvement over time.ResultsEighty‐seven subjects, 41 adults and 46 adolescents, were included; 59.8% were female and were aged between 11 and 44 years. The total acne lesion count decreased by 34%, the noninflammatory lesion count by 28%, and the inflammatory lesion count by 52% at Day 56. All % changes were statistically significant (p < 0.05). The GEA score decreased, with 25% of subjects showing at least a one‐grade improvement at Day 28 and 59% at Day 56. Local tolerance was excellent.ConclusionsThe tested DC care is beneficial for the improvement of acne and is very well tolerated in all skin phototypes studied.
Endoscopic malleostapedotomy versus incudostapedotomy for stapes fixation with or without lateral chain fixation: A comparative outcomes study
Authors: Son Hyo One , Moon Seoungjun , Sung Hanwool John , Choi Jin Woong 
Published: May 2024

AbstractObjectivesThis study aims to evaluate and compare the surgical outcomes of endoscopic malleostapedotomy (EMS) and endoscopic incudostapedotomy (EIS).MethodsA retrospective analysis was conducted on 36 consecutive ears in 33 patients who underwent stapes surgery using either EMS (EMS group) or EIS (EIS group). Operational practicability across surgical steps, postoperative hearing, operation time, switch of approach, and complications were compared between the two groups.ResultsThe EMS and EIS groups comprised seven (19.4%) and 29 ears (80.6%), respectively. The EMS group exhibited a greater proportion of moderate practicability in anchoring site exposure (42.9%, three of seven) and in securing the prosthesis (100%, seven of seven) in comparison to the EIS group, which had 0% (0 out of 29) and 41.4% (12 out of 29), respectively. Postoperative hearing improvements were equivalent between the groups, with EMS achieving a mean air‐bone gap improvement of 28.8 dB and EIS of 23.2 dB. The ABG closure rates within 10 dB and 20 dB for the EMS group were 28.6% and 100%, respectively, and not significantly different from the EIS group (p = .103). However, the average surgical duration for EMS was extended by 77.4 min. The rate of complications was comparable between the groups (EMS 14.3%, EIS 10.3%, p = 1.000).ConclusionThe findings indicate that while EMS requires a longer operation time because of decreased practicability in specific surgical steps, it provides comparable outcomes to EIS, underscoring the potential of endoscopic techniques to establish malleostapedotomy as a surgical option as it is with traditional incudostapedotomy.Level of Evidence4.
The role of a smile in customer–employee interactions: Primitive emotional contagion and its boundary conditions
Authors: Hofmann Verena , Stokburger‐Sauer Nicola E. , Wetzels Martin 
Published: May 2024

AbstractBy investigating emotional contagion in customer–employee interactions using the emotional facial action coding system, this study offers a means to separate primitive emotional contagion from its conscious counterpart. As an empirical validation of primitive emotional contagion and its impact on customer satisfaction, the multifaceted research approach, involving an experimental laboratory study and two field studies in hospitality and retail settings, reveals consistent findings. Additionally, the influence of emotional contagion on customer satisfaction is moderated by the esthetic appeal of the interior design. This work advances the theoretical understanding of the dynamics of primitive emotional contagion; it also offers practical insights regarding the importance of interior designs and busyness for enhancing service interactions.
R‐MFE‐TCN: A correlation prediction model between body surface and tumor during respiratory movement
Authors: Wang Xuehu , Yang Chang , Liu Ziqi , Zhang Jushuo , Xue Chao , Xing Lihong , Zheng Yongchang , Geng Chen , Yin Xiaoping 
Published: May 2024

AbstractBackground2D CT image‐guided radiofrequency ablation (RFA) is an exciting minimally invasive treatment that can destroy liver tumors without removing them. However, CT images can only provide limited static information, and the tumor will move with the patient's respiratory movement. Therefore, how to accurately locate tumors under free conditions is an urgent problem to be solved at present.PurposeThe purpose of this study is to propose a respiratory correlation prediction model for mixed reality surgical assistance system, Riemannian and Multivariate Feature Enhanced Temporal Convolutional Network (R‐MFE‐TCN), and to achieve accurate respiratory correlation prediction.MethodsThe model adopts a respiration‐oriented Riemannian information enhancement strategy to expand the diversity of the dataset. A new Multivariate Feature Enhancement module (MFE) is proposed to retain respiratory data information, so that the network can fully explore the correlation of internal and external data information, the dual‐channel is used to retain multivariate respiratory feature, and the Multi‐headed Self‐attention obtains respiratory peak‐to‐valley value periodic information. This information significantly improves the prediction performance of the network. At the same time, the PSO algorithm is used for hyperparameter optimization. In the experiment, a total of seven patients' internal and external respiratory motion trajectories were obtained from the dataset, and the first six patients were selected as the training set. The respiratory signal collection frequency was 21 Hz.ResultsA large number of experiments on the dataset prove the good performance of this method, which improves the prediction accuracy while also having strong robustness. This method can reduce the delay deviation under long window prediction and achieve good performance. In the case of 400 ms, the average RMSE and MAE are 0.0453 and 0.0361 mm, respectively, which is better than other research methods.ConclusionThe R‐MFE‐TCN can be extended to respiratory correlation prediction in different clinical situations, meeting the accuracy requirements for respiratory delay prediction in surgical assistance.
Simplified method for estimating the impact of the underlying tunnel excavation on existing tunnel
Authors: Feng Guohui , Xu Changjie , Ding Zhi , Liang Luju , Li Yujie , Xu Liyang , Fan Xiaozhen 
Published: May 2024

AbstractTunneling underneath is bound to induce the free displacement of surrounding soil, which will further significantly affect the overlying tunnel's deformation. Based on this, a simplified method for calculating the deformation of the overlying tunnel due to shield tunnel excavation is proposed. Firstly, the Loganathan formula is selected to solve the additional stress along the pre‐existing tunnel induced by tunneling underlying, then the overlying tunnel is further simplified into an infinitely Euler‐Bernoulli beam resting on the Pasternak foundation. The influence of the lateral soil reaction on the existing tunnel is introduced, then adopting the energy method to describe the soil and tunnel response. The minimum potential energy principle is utilised to solving the variational energy solutions due to new tunnel excavation underlying and further obtain the explicit solutions of tunnel response. The proposed method's effectiveness is confirmed through comparisons with centrifuge tests and field case studies obtained from prior research. In comparison with the Pasternak foundation model degenerated from the proposed method, the outcomes produced using the proposed method align more closely with the measurement data. Further parameter studies show that skew angle between tunnels, depth of existing tunnel, and volume loss rate are significant factors affecting the tunnel behaviors due to tunneling underneath.
Characteristics of Aqueous Chemical Species Generation in Plasma‐Facing Liquid Systems Using Helium Jet Plasma
Authors: Park Joo Young , Bae Jin Hee , Lee Seunghun 
Published: May 2024

AbstractPlasma‐facing liquids (PFLs) facilitate the storage of reactive O and N species (RONS), including H2O2 and NO2−, which remain in the PFL after plasma treatment, and they can continuously influence the target immersed in the liquid. However, their behaviors and levels of generation and extinction depend strongly on the plasma characteristics and liquid condition. Therefore, understanding the effects of the liquid type on the plasma discharge characteristics and the RONS generated via plasma discharge is necessary. We compared the RONS generation and storage trends of deionized H2O and a high‐conductivity PFL, RPMI 1640, which is a well‐known cell culture medium commonly used to culture mammalian cells. RPMI 1640 acted as an electrode and enhanced the plasma discharge power by supplying abundant radicals and RONS. The production of gaseous hydroxyl radicals and NO markedly increased, which facilitated H2O2 and NO2− production in the PFL for the first 200 s, and then the increase in the RONS concentration stagnated. With respect to storage, as the components within RMPI 1640 exhibited high reaction constants for their reactions with H2O2, H2O2 elimination was completed in <30 min. Unlike H2O2, the concentration of NO2− in the PFL was unchanged.
Investigating home‐based opioid use among youth with sickle cell disease using ecological momentary assessment
Authors: Valrie Cecelia , Crawford B. Sloan , Shipman‐Lacewell Jelaina , Ajibade Opeyemi , Fuh Beng , Smith Wally , Sisler India 
Published: May 2024

AbstractBackgroundOpioids are a common and essential treatment for acute sickle cell disease (SCD) pain. However, opioids carry well‐known adverse side effects, including potential development of hyperalgesia and nociplastic pain. We characterized opioid use in youth with SCD using ecological momentary assessment (EMA) data, and investigated the relationships between home‐based opioid use, pain, and a range of biopsychosocial factors.MethodEighty‐eight youth with SCD (aged 8–17 years) completed EMAs assessing home‐based opioid use, pain, and related factors. Analyses consisted of descriptive and multilevel logistic regression to predict daily home opioid use.ResultsYouth averaged 3.64 weeks of EMAs. Approximately 35% of the sample (n = 31) took an opioid during the EMA period, and used them on only 24% of reported pain days. Youth who took opioids reported a higher percentage of pain days (t = −2.67, p < .05) and mean pain severity scores (t = −2.30, p < .05) than youth who did not take opioids. Multilevel logistic regression analyses indicated that high daily pain severity (odds ratio [OR] = 1.02, p < .01), older age (OR = 1.324, p < .01), and low positive affect (OR = 0.91, p < .01) were each related to an increased likelihood of opioid use.ConclusionYouth with SCD take opioids appropriately in response to their pain, based on daily self‐report. Beyond daily pain severity, age, and daily variation in positive affect were related to home‐based opioid use. This suggests that behavioral interventions that enhance positive affect may promote reduced opioid use among youth with SCD.
The emerging application of ultrasound technology in pediatric bone fractures: Clinical application, related issues and development prospect
Authors: Li Xiang , Liu Xing , Shi Mingyan , Zhang Man , Wang Peikang , Zhang Xinkai 
Published: May 2024

AbstractUltrasonography has begun to be applied to the examination of fractures in recent years owing to its safety, noninvasiveness, portability, and high sensitivity. The subcutaneous soft tissue of children is thinner than that of adults, children's bones have a high level of elasticity and a low level of brittleness, and the pediatric fractures heal quickly and produce more callus, therefore ultrasonography is a more suitable examination in pediatric bone fractures. In this paper, we intend to review the mechanism, performance, and examination effect of ultrasound examination in bone fractures, analyze the advantages and disadvantages between ultrasound imaging and X‐ray imaging, and further propose an outlook for the application of ultrasound technology in pediatric bone fractures.