bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unusual luminescence of Ca8[Al12O24](WO4)2: Tb3+
Authors: Liu Sheng‐Li , Su Qiang 
Published: September 2010

AbstractThe luminescence properties of aluminate sodalite Ca8[Al12O24](WO4)2(CAW) un doped and doped with Tb3+are reported and discussed. At morn temperature the emission of tetrahedral WO42‐in CAW showed an abnormally small Stokes shift (9060 cm−1), which is related to the crystal structure of CAW. A strong absorption band in the excitation spectrum of the Tb3+‐activated CAW is ascribed to the absorption of the charge transfer state Tb4+‐W5+, into which the excitation resulted in the efficient emission from the5D4level of Tb3+, but not from the5D3level.
Preparation of luminol‐doped nanoparticle and its application in DNA hybridization analysis
Authors: Qian Ke‐Jun , Zhang Ling , Yang Min‐Li , He Pin‐Gang , Fang Yu‐Zhi 
Published: September 2010

AbstractThe dye‐doped silica nanoparticles can be used as nanobiosensors that are able to recognize and detect specific DNA sequence. In his paper, spherical nanosized luminol/SiO2 composite particles have been synthesized with reverse micells via hydrolysis of tetraethyl orthosilicate (TEOS) in the microemulsion. The nanoparticles were modified with chitosan and used to label DNA, forming the DNA probe which was used to hybridize with target DNA immobilized on a PPy modified Pt electrode. The hybridization events were evaluated by electro generated chemiluminescence's (ECL) measurements and only the complementary sequence could form a double‐stranded DNA (dsDNA) with DNA probe and give strong ECL signals. A three base mismatch sequence and a non‐complementary sequence had almost negligible responses. Due to the large number of luminol molecules inside silica nanoparticles, the assay allows detection at levels as low as 2.0×10−12 mol/L of the target DNA. The intensity of ECL was linearly related to the concentration of the complementary sequence in the range of 5.0×10−12‐1.0×10−9 mol/L.
Synthesis of fullerene‐acrylamide copolymer nanoball and its lubrication properties
Authors: Jiang Gui‐Chang , Guan Wen‐Chao , Zheng Qi‐Xin 
Published: September 2010

AbstractA novel fullerene‐acrylamide copolymer was synthesized via radical polymerization. It is soluble in polar solvents such as water, dimethyl sulfoxide etc. The product was characterized by FTIR, UV‐Vis and GPC. TEM analysis shows that the average particle diameter is about 46 nm. Four‐ball tests show that the addition of a certain concentration of the fullerene copolymer to base stock (2 wt% triethanolamine and 0.5 wt% OPZ aqueous solution) can effectively raise the load‐carrying capacity (Pb value) and the antiwear ability. SEM analysis shows that the addition results in reducing diameter of wear scar and decreasing wear.
Coupling reaction of organoboronic acids with chloropyrimidines and trichlorotriazine
Authors: Tan Jiu‐Qing , Chang Jian‐Hua , Deng Min‐Zhi 
Published: September 2010

AbstractPd‐catalyzed cross‐coupling reactions of chloropyrimidines with alkenylboronic acids readily proceed to give the corresponding alkenylpyrimidines in high to excellent yields. The coupling reaction of 2,4‐dichloropyrimidine or 2,4,6‐trichloropyrimidine with one equivalent of alkenylboronic acid occurred more easily on 4‐position than on 2‐position, which implied that the reaction is highly regioselective. The reaction is stereospecific since the configuration of C=C remained intact. The preliminary study on the cross‐coupling reactions of 2,4,6‐trichlorotriazine with one equivalent of arylboronic acids showed that the reactions afforded the monosubstituted triazines in moderate yields. The effect of steric hindrance of the substitutents on the reactions was found.
CO2as both a selective agent and reaction media in palladium‐catalyzed reductive Ullmann‐type coupling reaction
Authors: Li Jin‐Heng , Xie Ye‐Xiang 
Published: September 2010

AbstractCarbon dioxide as both a selective agent and reaction media in the palladium‐catalyzed Ullmann‐type coupling has been described. The results showed that aryl chlorides could be easily activated in the presence of carbon dioxide and the chemoselectivity shifted toward the palladium‐catalyzed Ullmann‐type coupling reaction. In liquid carbon dioxide, homocoupling reactions of aryl halides, including less reactive aryl chlorides, were carried out smoothly in moderate to good yields using Pd/C, zinc, and H2O as the catalytic system at room temperature.
Enantioseparation of novel chiral tetrahedral clusters on an amylose tris‐(3,5‐dimethylphenylcarbamate) chiral stationary phase by normal phase HPLC
Authors: Li Wen‐Zhi , Wang Xia , Zhang Wei‐Qiang , Li‐Ren Chen , Li Yong‐Min , Ma Chun‐Lin , Yin Yuan‐Qi 
Published: September 2010

AbstractAmylose tris(3,5‐dimethylphenylcamate) (ADMPC) coated on a kind of small particle silica gel was prepared. On this ADMPC chiral stationary phase (CSP), the direct enantiomeric separation of six novel chiral transition metal tetrahedral clusters has firstly been achieved using n‐hexane as the mobile phase containing various alcohols as modifiers. The effect of mobile phase modifiers and the structural variation of the solutes on their retention factors (k) and resolutions (Rs) were investigated. The result suggests that not only the structure and concentration of alcohol in mobile phase, but also the structural differences in racemates can have a pronounced effect on enantiomeric separation. ADMPC‐CSP is a suitable CSP for the optical resolution of chiral tetrahedral cluster by HPLC.
Studies on the interaction between rutin and DNA in the absence and presence of β‐cyclodextrin by electrochemical and spectroscopic methods
Authors: Yang Gong‐Jun , Xu Jing‐Juan , Chen Hong‐Yuan , Leng Zong‐Zhou 
Published: September 2010

AbstractThe interactions between rutin or the inclusion complex of rutin‐β‐cyclodextrin and DNA were investigated by means of cyclic voltammetry, UV‐vis absorption spectroscopy and fluorescence emission spectroscopy. The apparent binding constant of rutin with DNA is found to be 2.9 × 104 L/mol. The results showed that the benzopyranic‐4‐one plane of rutin mainly intercalated into DNA in the absence of β‐cyclodextrin, while the catecholic portion of rutin was located in the double helix of DNA in the presence of β‐cyclodextrin.
Spectroscopy investigation on conformational transition of tea glycoconjugate from green tea
Authors: Chen Hai‐Xia , Zhang Min , Xie Bi‐Jun 
Published: September 2010

AbstractThe conformational transition of a new glycoconjugate, tea glycoconjugate (TGC), was investigated by spectroscopy techniques including circular dichroism (CD) and ultraviolet (UN) spectroscopy. The solution behaviors of TGC in the mediums of different temperature, pH value, and ions were compared. Results showed that the native conformation of TGC was partially ordered. The CD value and UV absorbance of TGC altered with the change of pH value, temperature, the addition of ions, and also accompanied order‐disorder transition. Especially the conditions with temperature higher than the glass transition temperature (Tg=62°C), higher pH value or lower pH value will have the most impact on the conformation of TGC, which will destroy the hydrogen bonds between the TGC molecules. The results indicated that the outside factors play important roles on the stability of the conformation of TGC.
Socioeconomic factors associated with adjuvant hormone therapy use in older breast cancer survivors
Authors: Yen Tina W. F. , Czypinski Linda K. , Sparapani Rodney A. , Guo Changbin , Laud Purushottam W. , Pezzin Liliana E. , Nattinger Ann B. 
Published: September 2010

AbstractBACKGROUND:The authors sought to identify socioeconomic (SES) factors associated with adjuvant hormone therapy (HT) use among a contemporary population of older breast cancer survivors.METHODS:Telephone surveys were conducted among women (ages 65‐89 years) residing in 4 states (California, Florida, Illinois, and New York) who underwent initial breast cancer surgery in 2003. Demographic, SES, and treatment information was collected.RESULTS:Of 2191 women, 67% received adjuvant HT with either tamoxifen or an aromatase inhibitor (AI); 71% of those women were on an AI. When adjusting for multiple demographic and SES factors, predictors of HT use were better education (high school degree or higher), better informational/emotional support, and younger age (ages 65‐79 years). Race/ethnicity, income, and insurance coverage for medication costs were not associated with receiving HT. For those on HT, when adjusting for all other factors, women were more likely to receive an AI if they had insurance coverage for some or all medication costs, if they were wealthier, if they had better informational/emotional support, and if they were younger (ages 65‐69 years).CONCLUSIONS:The majority of older women in this population‐based cohort received adjuvant HT, and the adoption of AIs was early. The results indicted that providers should be aware that a woman's education level and support system influence her decision to take HT. Given the high cost of AIs, their benefits in postmenopausal women with hormone receptor‐positive breast cancer, and the current finding that women with no insurance coverage for medication costs were significantly less likely to receive an AI, we recommend that policymakers address this issue. Cancer 2011. © 2010 American Cancer Society.
L‐asparaginase treatment in acute lymphoblastic leukemia
Authors: Pieters Rob , Hunger Stephen P. , Boos Joachim , Rizzari Carmelo , Silverman Lewis , Baruchel Andre , Goekbuget Nicola , Schrappe Martin , Pui Ching‐Hon 
Published: September 2010

AbstractAsparaginases are a cornerstone of treatment protocols for acute lymphoblastic leukemia (ALL) and are used for remission induction and intensification treatment in all pediatric regimens and in the majority of adult treatment protocols. Extensive clinical data have shown that intensive asparaginase treatment improves clinical outcomes in childhood ALL. Three asparaginase preparations are available: the native asparaginase derived from Escherichia coli (E. coli asparaginase), a pegylated form of this enzyme (PEG‐asparaginase), and a product isolated from Erwinia chrysanthemi, ie, Erwinia asparaginase. Clinical hypersensitivity reactions and silent inactivation due to antibodies against E. coli asparaginase, lead to inactivation of E. coli asparaginase in up to 60% of cases. Current treatment protocols include E. coli asparaginase or PEG‐asparaginase for first‐line treatment of ALL. Typically, patients exhibiting sensitivity to one formulation of asparaginase are switched to another to ensure they receive the most efficacious treatment regimen possible. Erwinia asparaginase is used as a second‐ or third‐line treatment in European and US protocols. Despite the universal inclusion of asparaginase in such treatment protocols, debate on the optimal formulation and dosage of these agents continues. This article provides an overview of available evidence for optimal use of Erwinia asparaginase in the treatment of ALL. Cancer 2011. © 2010 American Cancer Society.
Gene therapy and enhancement for diabetes (and other diseases): the multiplicity of considerations
Authors: Bertolaso Marta , Olsson Jenny , Picardi Antonio , Rakela Jorge 
Published: September 2010

AbstractGene therapy has reached the forefront of studies and research over the last 30 years because of its potential for curing, treating, and preventing diseases associated with DNA mutations. Type 1 and type 2 diabetes are two examples of very common polygenic and multifactorial diseases. The huge amount of scientific literature on this topic reflects a growing general interest in the possibilities of altering our genetic heritage and thus controlling the onset of diseases associated with mutations and relative risk factors. We have focussed on the new treatment opportunities and possibility of enhancing an individual's health, physical well‐being, and even an individual's behaviour through technologies specially designed for therapeutic purposes, which have been presented in literature. This historical perspective shows how this type of research, however, was immediately subjected to an ethical evaluation, especially regarding the decoding of the human genome and the questions raised by the alteration of our genetic heritage through new biotechnologies. Moreover, understanding the limitations of gene therapy protocol experiments and the multifactorial nature of many diseases, which have a genetic base, also contributes to these considerations. Copyright © 2010 John Wiley & Sons, Ltd.
Thermooxidative stability of vegetable oils refined by steam vacuum distillation and by molecular distillation
Authors: Šimon Peter , Cvengroš Ján 
Published: September 2010

AbstractSemi‐refined rapeseed and sunflower oils after degumming and bleaching were refined by deodorization and deacidification in two ways, i.e., by steam vacuum distillation in the deodorization column Lurgi and by molecular distillation in the wiped‐film evaporator. The oxidative stability of the oils before and after the physical refining has been evaluated using non‐isothermal differential scanning calorimetry. Treatment of the experimental data was carried out by applying a new method based on a non‐Arrhenian temperature function. The results reveal that refining by molecular distillation leads to lower oxidative stability of the oils than refining by steam vacuum distillation.Practical applications: (i) A method for the refining of edible oils by the molecular distillation in the wiped film of a short‐path evaporator is presented and applied. (ii) Oxidative stability of the oils refined by molecular distillation and steam vacuum distillation is compared. It has been found that refining by molecular distillation leads to lower oxidative stability of the oils than refining by steam vacuum distillation. (iii) Experimental data were treated by applying a new method based on a non‐Arrhenian temperature function. The method enables trustworthy predictions of oil stabilities for the application temperatures.
Protecting‐Group Directed Stereoselective Intramolecular Nozaki–Hiyama–Kishi Reaction: A Concise and Efficient Total Synthesis of Amphidinolactone A (Eur. J. Org. Chem. 25/2010)
Authors: Mohapatra Debendra K. , Das Pragna P. , Pattanayak Manas R. , Gayatri Gaddamanugu , Sastry G. Narahari , Yadav J. S. 
Published: September 2010

AbstractThe cover picture shows shows how a bulky protecting group directs the intramolecular Nozaki–Hiyama–Kishi reaction to afford exclusively one stereoisomer, whereas a small protecting group directs the reaction to afford both anti and syn isomers in a 2:1 ratio. Details are discussed in the article by D. K. Mohapatra, J. S. Yadav et al. on p. 4775 ff.
The Influence of the Cathodic Pretreatment on the Electrochemical Detection of Dopamine by Poly(1‐aminoanthracene) Modified Electrode
Authors: de Pieri Troiani Estela , Faria Ronaldo Censi 
Published: September 2010

AbstractIn this study we demonstrated the influence of the cathodic pretreatment of poly(1‐aminoanthracene) (PAA) electropolymerized on a platinum electrode for determination of dopamine (DA). The DA electrochemical response was obtained after a cathodic pretreatment of the PAA electrode which consisted of applying a potential of −0.7 V (vs. Ag/AgCl) for 3 s before each measurement. The pretreatment of the electrode changed the PAA electrocatalytic properties so that the electrode began to present electrochemical response to DA without interference of ascorbic acid (AA). The anodic peak currents determined by differential pulse voltammetry using pretreated PAA showed a linear dependence on the DA concentration from 0.56 to 100 µM with a detection limit of 0.13 µM and a correlation coefficient of 0.9986. The electrode exhibits a relative standard deviation of 1.2 % for ten successive measurements of a 0.5 mM DA solution. The analysis by scanning electron microscopy and atomic force microscopy show a homogeneous and nanostructured film with globular structures with diameter of about 20 nm. The analytical results obtained for DA determination at a pretreated PAA electrode in pharmaceutical formulation sample were in good agreement with those obtained by a comparative procedure at a 95 % confidence level. PAA electrode after the pretreatment showed electrochemical responses to DA with excellent selectivity, sensitivity, and high stability without interference of AA.
Modeling strength degradation in lead–rubber bearings under earthquake shaking
Authors: Kalpakidis Ioannis V. , Constantinou Michael C. , Whittaker Andrew S. 
Published: September 2010

AbstractLead–rubber bearings are seismic isolators that have been used extensively to protect buildings, bridges and mission‐critical infrastructure from the damaging effects of earthquake shaking. Under large‐displacement cyclic motion, the strength of a lead–rubber bearing reduces due to energy dissipation and the resultant heating of the lead core. This paper proposes a method to incorporate strength degradation due to lead core heating in modeling the hysteretic behavior of lead–rubber bearings. The validity of the proposed model is investigated through comparing numerical and experimental results. The model is used to examine the effects of lead core heating on the dynamic response of an isolated structure. Copyright © 2010 John Wiley & Sons, Ltd.
Nasal morbidity following endoscopic skull base surgery: A prospective cohort study
Authors: de Almeida John R. , Snyderman Carl H. , Gardner Paul A. , Carrau Ricardo L. , Vescan Allan D. 
Published: September 2010

AbstractBackground.Nasal morbidity following skull base surgery necessitates follow‐up for postoperative care. We describe nasal morbidity following endoscopic skull base surgery.Methods.Patient and operative data and postoperative subjective and objective measures of morbidity were prospectively collected for 1 year. Time to absence of crusting and remucosalization were determined. Risk factor analyses for crusting and nasal discharge were performed.Results.Nasal crusting (98%) and discharge (46%) were the most common postoperative symptoms. Median time to absence of crusting was 101.0 days, with longer times for complex cases (p = .033) but not for patients with septal flaps or fat grafts. Median time to remucosalization after nasoseptal flap was 89.0 days. There were no risk factors for crusting, although surgical complexity was a risk factor for postoperative discharge (odds ratio [OR] = 5.17).Conclusions.Nasal morbidity following endoscopic skull base surgery is common and may be affected by surgical complexity and use of the nasoseptal flap. © 2010 Wiley Periodicals, Inc. Head Neck, 2011
Exercise increases insulin signaling in the hippocampus: Physiological effects and pharmacological impact of intracerebroventricular insulin administration in mice
Authors: Muller Alexandre P. , Gnoatto Jussânia , Moreira Julia D. , Zimmer Eduardo R. , Haas Clarissa B. , Lulhier Francisco , Perry Marcos L.S. , Souza Diogo O. , Torres‐Aleman Ignácio , Portela Luis V. 
Published: September 2010

AbstractIncreasing evidence indicates that physical exercise induces adaptations at the cellular, molecular, and systemic levels that positively affect the brain. Insulin plays important functional roles within the brain that are mediated by insulin‐receptor (IR) signaling. In the hippocampus, insulin improves synaptic plasticity, memory formation, and learning via direct modulation of GABAergic and glutamatergic receptors. Separately, physical exercise and central insulin administration exert relevant roles in cognitive function. We here use CF1 mice to investigate (i) the effects of voluntary exercise on hippocampal insulin signaling and memory performance and (ii) whether central insulin administration alters the effects of exercise on hippocampal insulin signaling and memory performance. Adult mice performed 30 days of voluntary exercise on running wheel and afterward both, sedentary and exercised groups, received intracerebroventricular (icv) injection of saline or insulin (0.5–5 mU). Memory performance was assessed using the inhibitory avoidance and water maze tasks. Hippocampal tissue was measured for [U‐14C] glucose oxidation and the immunocontent of insulin receptor/signaling (IR, pTyr, pAktser473). Additionally, the phosphorylation of the glutamate NMDA receptor NR2B subunit and the capacity of glutamate uptake were measured, and immunohistochemistry was used to determine glial reactivity. Exercise significantly increased insulin peripheral sensitivity, spatial learning, and hippocampal IR/pTyrIR/pAktser473 immunocontent. Glucose oxidation, glutamate uptake, and astrocyte number also increased relative to the sedentary group. In both memory tasks, 5 mU icv insulin produced amnesia but only in exercised animals. This amnesia was associated a rapid (15 min) and persistent (24 h) increase in hippocampal pNR2B immunocontent that paralleled the increase in glial reactivity. In conclusion, physical exercise thus increased hippocampal insulin signaling and improved water maze performance. Overstimulation of insulin signaling in exercised animals, however, via icv administration impaired behavioral performance. This effect was likely the result of aberrant phosphorylation of the NR2B subunit. © 2010 Wiley‐Liss, Inc.
Infants' use of material properties to guide their actions with differently weighted objects
Authors: Paulus Markus , Hauf Petra 
Published: September 2010

AbstractTwo studies with 9‐, 11‐ and 13‐month‐old infants were conducted to investigate infants' ability to use an object's material properties to guide their object‐directed actions. In study 1, 9‐ and 11‐month‐old infants played in an exploration phase with two objects made of different materials, one very heavy and the other one light and playable. Subsequently, when given the choice between both objects in a preferential reaching task, only the 11‐month‐olds' used the object's material information to remember and choose the lighter object. In study 2, 11‐ and 13‐month‐old infants underwent the same exploration phase. In the test phase, novel objects made of the same materials were offered. The 13‐ but not the 11‐month‐olds chose the objects made from the same material as the lighter object in the exploration phase. Additionally, infants' performances in the reaching task were positively correlated with their exploratory behaviour during the exploration phase. Altogether, the studies show a developmental progression in the use of an object's material information to guide infants' action. The results are discussed in respect to infants' perception of object properties and their implications for the development of physical knowledge. Copyright © 2010 John Wiley & Sons, Ltd.