bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ventajas y desventajas del uso de las Herramientas de Inteligencia artificial en la educación
Authors: Guaña Moya Javier , Arteaga-Alcívar Yamileth , Cedeño Zambrano María Elizabeth 
Published: April 2024

Este trabajo se enfoca en explorar las ventajas y desventajas del uso de herramientas de inteligencia artificial (IA) en la educación. La revisión de la literatura identificó diversas ventajas, incluyendo la personalización del aprendizaje, la retroalimentación inmediata y la eficiencia en la gestión educativa. Sin embargo, también se identificaron desventajas importantes, como la falta de interacción humana y el potencial de agravar las desigualdades educativas existentes. La metodología utilizada incluyó una revisión sistemática de la literatura y una búsqueda en bases de datos relevantes. Los resultados sugieren que el uso de herramientas de IA puede mejorar la eficiencia en la gestión educativa y ofrecer retroalimentación personalizada y adaptativa a los estudiantes. Además, estas herramientas pueden personalizar el aprendizaje y adaptarse a las necesidades individuales de cada estudiante, mejorando la calidad y la efectividad de la enseñanza.
Sin embargo, también se encontraron desafíos importantes relacionados con la privacidad y seguridad de los datos, la responsabilidad ética y legal de la implementación de tecnologías de IA en la educación, y la necesidad de abordar los sesgos y la discriminación potencial en los algoritmos de IA. En conclusión, el uso de herramientas de IA en la educación es una tendencia emergente y prometedora, pero requiere una reflexión cuidadosa y un enfoque estratégico para asegurar que se utilicen de manera efectiva y responsable. Es importante que los educadores y las escuelas trabajen juntos para garantizar que el uso de herramientas de IA beneficie a todos los estudiantes, sin aumentar las desigualdades educativas y sin comprometer la calidad y la efectividad de la enseñanza.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KONDISI FINANCIAL DISTRESS (STUDI EMPIRIS PERUSAHAAN SUBSEKTOR FOOD AND BEVERAGE YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2018-2020)
Authors: Yunas Shafa Kamila , Bawono Andi Dwi Bayu 
Published: April 2024

Financial Distress merupakan suatu kondisi dimana sebuah perusahaan berada dalam kondisi tidak aman atau mengalami kesulitan keuangan karena tidak dapat memenuhi kewajibannya pada saat jatuh tempo. Financial Distress dapat terjadi karena beberapa faktor salah satunya yaitu jumlah hutang dan kewajiban perusahaan yang semakin meningkat sehingga perusahaan mengalami kerugian. Penelitian ini bertujuan untuk mengetahui pengaruh likuiditas, profitabilitas, leverage, intellectual capital dan working capital to total assets terhadap financial distress pada perusaahaan subsektor food and beverage dengan menggunakan model Altman Z-Score. Variabel independen yang digunakan dalam penelitian ini yaitu likuiditas, profitabilitas, leverage, intellectual capital dan working capital to total assets. Penelitian ini menggunakan data sekunder yang diperoleh dari laporan keuangan perusahaan manufaktur subsektor food and beverage yang terdaftar di Bursa Efek Indonesia selama tahun 2018-2020. Sampel dalam penelitian ini sebanyak 72 (tujuh puluh dua) perusahaan. Teknik pengambilan sampel menggunakan teknik purposive sampling. Analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif dan uji regresi linier berganda dengan menggunakan IBM SPSS 25.0. Berdasarkan pengujian terhadap hipotesis yang dilakukan, dapat disimpulkan bahwa variabel likuiditas tidak berpengaruh terhadap financial distress, profitabilitas tidak berpengaruh terhadap financial distress dan intellectual capital tidak berpengeruh terhadap financial distress. Sedangkan variabel leverage dan working capital to total assets yang berpengaruh terhadap financial distress
PENGELOLAAN DESAIN LINGKUNGAN KELOMPOK BERMAIN
Authors: Ramdhani Ambar Putri , Sari Fuji Punjung , Wulandari Retno 
Published: April 2024

Pengelolaan desain lingkungan PAUD adalah penataan tepatnya set plan tampilan indoor maupun outdoor PAUD. Desain lingkungan meliputi lingkungan diluar ruangan (outdoor) dan di dalam ruangan (indoor). Lingkungan belajar indoor adalah lingkungan belajar yang memang sudah disediakan oleh manajemen sekolahan agar digunakan untuk para siswanya sebagai sumber belajar atau lingkungan belajar yang ada didalam sekolahan tersebut. Tujuan dari penelitian ini ialah untuk menganalisis pengelolaan desain lingkungan di Kelompok Bermain. Penelitian ini menggunakan pendekatan kualitatif yaitu dimana mendeskripsikan tentang pengelolaan desain lingkungan di Kelompok Bermain. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah studi kepustakaan (Library Research) dimana studi kepustakaan adalah kegiatan mengumpulkan bahan-bahan yang berkaitan dengan penelitian yang berasal dari buku, jurnal ilmiah, literatur-literatur dan publikasi lain yang layak dijadikan sumber untuk penelitian yang akan diteliti penulis, dengan cara mendeskripsikan data tersebut melalui beberapa pendapat para ahli.
EDUKASI BAHAYA SEKS BEBAS PADA REMAJA DI KELURAHAN KALOSI KECAMATAN ALLA KABUPATEN ENREKANG
Authors: Anisa Nurul Rezki , Sabil Fitri A. , Abrar Eva Arna , Fauzia Liza 
Published: April 2024

Abstrak
Seks bebas merupakan isu dan tren yang diminati kelompok usia remaja saat ini. Hal tersebut merupakan masalah sosial yang memerlukan informasi yang tepat agar tidak berdampak pada munculnya masalah kesehatan yang lain pada remaja. Misalnya timbulnya penyakit Human Inmunodeficiency Virus (HIV) dan Acquired Immune Defficiency Syndrome (AIDS). Selain penyakit tersebut, peningkatan kasus aborsi yang terjadi di Indonesia juga diketahui merupakan dampak dari perilaku seks bebas di kalangan remaja. Oleh karena itu, penting untuk memberi edukasi dan penyuluhan kepada remaja mengenai bahasa dari perilaku seks bebas. Metode kegiatan pengabdian masyarakat ini dilakukan dengan memberikan penyuluhan melalui media zoom kepada 15 remaja selama 60 menit mengenai perilaku dan permasalahan dari seks bebas. Hasil yang diperoleh dari kegiatan ini yaitu adanya kesadaran remaja untuk menjauhi perilaku seks bebas dan dapat mengedukasi teman sebaya. Remaja yang mengikuti kegiatan terlihat antusias dan termotivasi untuk menjadi kader pemberi informasi mengenai bahaya seks bebas.

Abstract
Free sex is a trend and issue which is in demand by today's youth age group. This is a social problem that requires accurate information so that it does not have an impact on the emergence of other health problems in adolescents. For example, the emergence of Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS). In addition to these diseases, the increase in abortion cases in Indonesia is also known to be the impact of free sex behavior among teenagers. Therefore, it is important to provide education and counseling to teenagers about the language of free sex behavior. This community service activity method is carried out by providing counseling through the media zoom to 15 teenagers for 60 minutes regarding the behavior and problems of free sex. The results obtained from this activity are the awareness of teenagers to stay away from free sex behavior and can educate their peers. Teenagers who take part in the activity look enthusiastic and motivated to become a cadre of information providers about the dangers of free sex.
PENDAMPINGAN DAN PELATIHAN PEMBUATAN PUPUK KOMPOS LIMBAH PETERNAKAN DI DESA NGAWUN KABUPATEN TUBAN
Authors: Rastono Adi , Muzadi Masrur , Siswara Hamzah Nata 
Published: April 2024

Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan dan keterampilan masyarakat Desa Ngawun Kecamatan Parengan Kabupaten Tuban dalam memanfaatkam limbah peternakan menjadi kompos. Warga masih memiliki beberapa keterbatasan dalam pengolahan antara lain, 1) pemahaman tentang teknologi pengolahan limbah ternak masih kurang, 2) belum memiliki keterampilan dalam mengelola limbah peternakan sehingga perlu adanya pendampingan dan pelatihan. Metode yang dilakukan dalam program pengabdian masyarakat adalah observasi melalui preetest dan postest, sosialisasi, pendampingan dan pelatihan pembuatan pupuk. Hasil dari kegiatan ini adalah Program ini berhasil dalam memotifasi warga untuk memanfaatkan limbah ternak menjadi kompos yang ditujukan prosentase preetest yang menjawab “Ya” adalah 31,3% dan “Tidak” 61,7%, namun setelah dilakukan kegiatan pendampingan dan pelatihan dalam pembuatan pupuk kompos prosentase pada posttest meningkat yaitu dengan jawaban “Ya” 80% sedangkan “Tidak” 20%.
EDUKASI PERAWATAN POSTPARTUM PADA IBU YANG MENGKONSUMSI RUJAK DAN OBAT BALANGA YANG TEPAT DI KECAMATAN BANDA NEIRA
Authors: Hasifah Hasifah , La Isa Wa Mina 
Published: April 2024

Latar Belakang: Angka kematian ibu (AKI) di Indonesia di dunia pada tahun 2015 mencapai 303.000 jiwa, setiap hari AKI sebanyak 830 akibat komplikasi kehamilan dan persalinan. Salah satu penyebab AKI meningkat adalah ketidaksesuaian praktik budaya pengobatan postpartum secara tradisional sehingga perlu adanya perawatan postpartum yang benar dalam menekan komplikasi pada postpartum. Perawatan postpartum meliputi perawatan perineum dan vulva hygiene, melakukan mobilisasi dini, melakukan perawatan payudara, meningkatkan kebutuhan nutrisi, pemenuhan eliminasi urin dan bowel yang teratur, pemenuhan kebutuhan seksual dan kebutuhan istirahat dan tidur.
Skrining Fitokimia Ekstrak Etanol Rimpang Kunyit Putih Curcuma Zedoaria (Christm.) Roscoe
Authors: Firmansyah Tiar , Jawa La Elisabeth Oriana 
Published: April 2024

Intisari
Kunyit putih (Curcuma zedoaria) merupakan salah satu tanaman yang banyak dimanfaatkan sebagai obat tradisional karena kandungan metabolit sekundernya yang banyak seperti alkaloid, saponin, terpenoid, flavonoid dan tanin. Kunyit putih secara farmakologi digunakan untuk antibakteri, antioksidan dan anti hepatotoksik. Tujuan dari penelitian ini untuk mengetahui kandungan senyawa aktif yang terdapat pada ekstrak etanol rimpang kunyit putih (Curcuma zedoaria) dengan menggunakan skrining fitokimia. Skrining fitokimia yang dilakukan meliputi identifikasi alkaloid, saponin, terpenoid, flavonoid dan tanin. Hasil skrining fitokimia ekstrak etanol rimpang kunyit putih (Curcuma zedoaria) mengandung golongan alkaloid, saponin, terpenoid, steroid, flavonoid dan tanin.
Kata kunci: ekstrak, kunyit putih, skrining fitokimia
Uji In Silico Molecular Docking Pinostrobin Sebagai Agen Anti-Inflamasi
Authors: Priastari Anak Agung Istri Manik 
Published: April 2024

Peradangan atau inflamasi merupakan respon alami tubuh terhadap cedera dan gangguan oleh faktor eksternal dan mempersiapkan keadaan untuk perbaikan jaringan. Pengobatan inflamasi dapat dilakukan dengan pengobatan secara tradisional menggunakan bahan alam yang berkhasiat sebagai agen anti-inflamasi. Salah satu tanaman yang diduga memiliki aktivitas sebagai anti-inflamasi adalah temu kunci dengan kandungan kimianya yaitu pinostrobin. Penelitian ini bertujuan untuk mengetahui mekanisme penghambatan ICE oleh pinostrobin dengan menggunakan docking molekuler in silico. Molecular docking secara in silico dilakukan dengan beberapa tahapan seperti optimasi struktur senyawa pinostrobin 3D, preparasi protein target, validasi metode, dan docking antara senyawa pinostrobin teroptimasi dengan enzim ICE (PDB ID: 1RWK) yang mengacu pada parameter energi ikatan dimana semakin rendah nilai energi ikatan maka semakin kuat dan stabil ikatan yang terjadi antara senyawa pinostrobin dengan enzim ICE. Diperoleh hasil docking berupa energi ikatan senyawa pinostrobin dengan enzim ICE yaitu -4,80 kkal/mol, sedangkan energi ikatan native ligand dengan enzim ICE adalah -3,92 kkal/mol. Energi ikatan tersebut menunjukkan bahwa senyawa pinostrobin memiliki potensi sebagai agen antiinflamasi karena mampu menghambat enzim ICE.
Current Issues of The Utilization of Online Dispute Resolution As A Method For International Trade Dispute Settlement
Authors: Rohmah Nuzul Quraniati 
Published: April 2024

The transformation of international trade from conventional to digital impacts several things, including resolving international trade disputes. In order to realize an efficient and effective dispute resolution process, many countries have implemented ODR to settle international trade disputes. This study aims to analyze the implementation of ODR in various countries and examine issues with unclear guidelines based on international law. This research observes the development of ODR in Indonesia and the urgency for its implementation in Indonesia. The research is normative juridical, with a statutory and comparative approach. The results obtained in this study are model law arrangements relating to the standardization of ODR Providers aimed to protect the personal data of the parties, unification of ODR dispute resolution clauses, and formulation of national legal instruments to create legal certainty regarding ODR, including ODR proceedings, permits, and monitoring, as well as recognition and execution process of electronic ODR decisions.
Incidence and risk factors of systemic lupus erythematosus in patients with primary immune thrombocytopenia: a systematic review and meta-analysis
Authors: Zhou En-min , Shen Heping , Wang Di , Xu Weiqun 
Published: April 2024

Background
Immune disorders and autoantibodies has been noted in both primary immune thrombocytopenia (ITP) and systemic lupus erythematosus (SLE). Whether the two disorders are correlated is unclear. The lack of evidence on the incidence of and risk factors for SLE in primary ITP patients poses a challenge for prediction in clinical practice. Therefore, we conducted this study.

Methods
The protocol was registered with PROSPERO (CRD42023403665). Web of Science, Cochrane, PubMed, and EMBASE were searched for articles published from inception to 30 September 2023 on patients who were first diagnosed with primary ITP and subsequently developed into SLE. Furthermore, the risk factors were analyzed. Study quality was estimated using the Newcastle-Ottawa Scale. The statistical process was implemented using the R language.

Results
This systematic review included eight articles. The incidence of SLE during the follow-up after ITP diagnosis was 2.7% (95% CI [1.3–4.4%]), with an incidence of 4.6% (95% CI [1.6–8.6%]) in females and 0 (95% CI [0.00–0.4%]) in males. Older age (OR = 6.31; 95% CI [1.11–34.91]), positive antinuclear antibody (ANA) (OR = 6.64; 95% CI [1.40–31.50]), hypocomplementemia (OR = 8.33; 95% CI [1.62–42.91]), chronic ITP (OR = 24.67; 95% CI [3.14–100.00]), organ bleeding (OR = 13.67; 95% CI [2.44–76.69]), and female (OR = 20.50; 95% CI [4.94–84.90]) were risk factors for subsequent SLE in ITP patients.

Conclusion
Patients with primary ITP are at higher risk of SLE. Specific follow-up and prevention strategies should be tailored especially for older females with positive ANA, hypocomplementemia, or chronic ITP. In subsequent studies, we need to further investigate the risk factors and try to construct corresponding risk prediction models to develop specific prediction strategies for SLE.
Development of Regenerative Tea Cultivation Models through Dual Approach of Soil and Plant Health Management towards Crop Sustainability, Soil Quality Development, Pesticide Reduction and Climate Change Mitigation: A Case Study from Lakhipara Tea Estate, Dooars, West Bengal, India (PART-II)
Authors: Bera R.  , Datta A  , Bose S.  , Barik A.K.  , Asthana A.  , Seal A.  
Published: April 2024

The first part of this research article documents the impact of the studied Regenerative Agriculture models in tea in respect of crop sustainability, pesticide load reduction and reduction of pest management cost. The findings indicated an increase (78 kg/ha) in crop productivity in the project area as against crop loss of 118 kg/ha in the non- project area during the same period. The finding also indicated a 52 to 77% reduction in the accumulated toxicity potential of the applied pesticides, improvement of soil quality indices and a 6.72% increase in the soil organic carbon stock. Most importantly, carbon assessment in terms of kg CO2 equivalent/ kg made tea (using ACFA version 1.0) indicated approximately 65 to 70 % lower footprint in the project area. The lowering of carbon footprint was due to a 20 to 30 % reduction in the chemical fertilizers along with improvement in carbon sequestration potential of the soil due to quality compost application and reduction of herbicides. The study indicated that Inhana Rational Farming (IRF) Technology can serve as an effective tool towards development of resource based Regenerative Agriculture Models that can ensure safe and low carbon tea cultivation without compromising crop yield and without increasing the cost of cultivation.
Streptococcus pneumoniae Nasopharyngeal Colonization and Antibiogram of Isolates from Paediatric Population in Enugu, South East Nigeria
Authors: Eleazar Clara Idara , Udoh Iniekong Philip , Madaukor Uzomaka Charity , Emenuga Veronica Ngozi , Nweke Rita Ngozi 
Published: April 2024

Aims: This research aimed to evaluate and identify Streptococcus pneumoniae from nasopharynx samples of children and carry out antibiotic susceptibility assay on the isolates; being that pneumococci is well noted as a significant cause of invasive pneumonia in infants with the challenge of antibiotic resistance, which may worsen due to the emergence of such strains among children population.
Methodology: This was a descriptive, cross-sectional study conducted between March and September 2023 in the Nsukka area of Enugu. Samples were collected from 100 children population using sterile swab sticks. These were inoculated unto blood and chocolate agar and then incubated at 37o C, morphological and biochemical characteristics were used for identification. An antimicrobial susceptibility test using the disk diffusion method was performed on isolates. The multi-discs used were pefloxacin 10ug, Gentamicin 10ug, Ampiclox 30ug, Cefuroxime 20ug, Amoxacillin 30ug, Ceftriazone 25ug, Ciprofloxacin 10ug, and Streptomycin 30ug, Co-tirmoxazole 30ug, and, Erythromycin 10ug.
Results: The results identified 8.0% of pediatric with pneumococcal carriage. Males were 10.0% while females were 5.0%. The age distributions were as follows: 0-5 years 4(8.7%), 6-10 years 1(3.1%), 11-15 years, 3(13.6%). There was no significant difference in the age range distribution of the pneumococci colonization (p=0.074). There was 66.7% sensitivity rate of S. pneumonia. The resistant rates were 75% each to Ampiclox and Amoxicillin. Cefuroxime was 87.5% resistant.
Design of a Circular Micro-strip Patch Antenna for Improved Directivity and Gain of Mobile Communication Base Station
Authors: Okoh Simon , Okhaifoh J. E. 
Published: April 2024

This study presents the design of Circular Micro-strip Patch Antenna (CMPA) for improved directivity and gain of mobile communication base station. The design incorporates a Rogger/5880 substrate material with a permittivity of 2.2, tangent angle of 0.00009 and a substrate height (thickness) of 0.98μm at a frequency of 1.65THz. Diversity Antenna Array Processing (DAAP) and Chebyshev Antenna Array (CAA) methods were used in the design. AutoCAD software and 2D data plotter were used for the diagrams and charts while Maple software was used for simulation. For angles of 0o, 30o, 60o, 90o, 120o, 150o and 180o, the array factors are 7.84dB, 7.85dB, 7.87dB, 7.88dB, 7.87dB, 7.85dB and 7.84db respectively. The results from the design demonstrated a remarkably low side lobe level of 0.01dB, indicating excellent suppression of unwanted radiation in undesired directions. Additionally, the antenna exhibits a Voltage Standing Wave Ratio (VSWR) of unity, ensuring maximum power transfer efficiency from the source to the load. Furthermore, the antenna shows a high directivity and gain of approximately 9dB, which enhances the signal strength and coverage range. The Half Power Beam-width (HPBW) and First Null Beam-width (FNBW) was measured as 300 and 600 respectively. These parameters depict the angular width of the main radiation beam and the sharpness of the beam pattern’s nulls. In all, the designed CMPA with its CAA based antenna array holds great potential for communication networks and for mobile communication base station, offering enhanced performance in terms of radiation characteristics and signal quality.
Lilium: A High-Value Cut Flower Production Guide for Lucrative Return
Authors: Samantaray Prachurjya , Nayak Aradhana , Pradhan Itishree , Pattanaik Akanshya , Sahoo Reshma , Mohanty Sukirti 
Published: April 2024

Lilium sp. is cultivated worldwide and is one of the most important generators cut flower and pot plant. In terms of the production and marketing of its cut flowers on the global cut flower market, this genus is quite important economically. The majority of the monocot perennial species in the genus Lilium are vegetatively propagated and are among the most significant flower bulbs in terms of economic impact. They are native to Asia, Europe, and North America. Asiatic and Oriental hybrid lilies are the most important groups and are derived from interspecific crosses of the Sinomartagon and Archelirion sections, respectively. Seed, bulb division, bulb scales, stem bulblets, stem bulbils (in some species), and tissue culture are all methods of multiplying lilies. The primary means of propagating Lilium are bulbs. Six to eight weeks after the parent bulbs begin to produce flowers, the small bulbs are removed. In the north Indian environment, mid-September to mid-December is the ideal period to plant hybrid lilies. October through November is a good season to grow Asiatic lilies in the Northern Plains, whereas March through April is a good time to plant in the hills. After 90 to 120 days of sowing, flowers are ready for harvesting. Cutting the flowers in the morning is ideal. The flower stalk should be clipped 8–10 cm above the ground as soon as the first blossom begins to take on color.
Escherichia coliLactose Operon
Authors: Ullmann Agnes 
Published: March 2009

AbstractThe study ofEscherichia colilactose operon laid the foundation of modern molecular biology. It contributed to the elaboration of the concept of genetic regulation, proposed by Jacob and Monod almost 50 years ago, a model which survives essentially unchanged. The operon structure, consisting of structural and regulatory genes has been elaborated and their regulatory response to small molecules, such as inducer, glucose and cyclic AMP, have been elucidated. Gene regulation of the lactose operon led to the discovery of messengerribonucleic acid(mRNA), to the identification of the Lac repressor and to the development of the theory of allostery. The lactose genes and its derivatives provide tools to a wide range of current applications in many fields of biology; they are the most commonly used reporter genes in the analysis of developmentally regulated systems, in the study of mutation frequencies and in functional genomics.
Major Histocompatibility Complex: Disease Associations
Authors: Alper Chester A 
Published: March 2009

Abstract

Human major histocompatibility complex (MHC) alleles can be used as markers for a wide variety of autoimmune and other disorders. The interpretation of and possible bases for these associations can be considered in relation to conserved extended MHC haplotypes (CEHs). The latter are fixed stretches of up to several million base pairs of genomic
deoxyribonucleic acid
(DNA). CEHs constitute at least a third of normal European Caucasian MHC haplotypes and contribute most of the MHC disease susceptibility genetic markers. Whereas this has facilitated the detection of MHC gene‐disease association, it paradoxically makes the identification of true susceptibility genetic loci (as distinguished from genetic markers) more difficult. It is likely that the great majority of true susceptibility genes for MHC‐associated diseases are yet to be discovered. It may take new methods and new approaches to identify the true MHC susceptibility genes and their relation to many of the polygenic MHC‐associated diseases.