bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short‐term information processing, long‐term responses: Insights by mathematical modeling of signal transduction
Authors: Schneider Annette , Klingmüller Ursula , Schilling Marcel 
Published: April 2012

AbstractHow do cells interpret information from their environment and translate it into specific cell fate decisions? We propose that cell fate is already encoded in early signaling events and thus can be predicted from defined signal properties. Specifically, we hypothesize that the time integral of activated key signaling molecules can be correlated to cellular behavior such as proliferation or differentiation. The identification of these decisive key signal mediators and their connection to cell fate is facilitated by mathematical modeling. A possible mechanistic linkage between signaling dynamics and cellular function is the directed control of gene regulatory networks by defined signals. Targeted experiments in combination with mathematical modeling can increase our understanding of how cells process information and realize distinct cell fates.
Different mechanisms of action of poly(ethylene glycol) and arginine on thermal inactivation of lysozyme and ribonuclease A
Authors: Tomita Shunsuke , Nagasaki Yukio , Shiraki Kentaro 
Published: April 2012

AbstractProteins tend to undergo irreversible inactivation through several chemical modifications, which is a serious problem in various fields. We have recently found that arginine (Arg) suppresses heat‐induced deamidation and β‐elimination, resulting in the suppression of thermal inactivation of hen egg white lysozyme and bovine pancreas ribonuclease A. Here, we report that poly(ethylene glycol) (PEG) with molecular weight 1,000 acts as a thermoinactivation suppressor for both proteins, especially at higher protein concentrations, while Arg was not effective at higher protein concentrations. This difference suggests that PEG, but not Arg, effectively inhibited intermolecular disulfide exchange among thermally denatured proteins. Investigation of the effects of various polymers including PEG with different molecular weight, poly(vinylpyrolidone) (PVP), and poly(vinyl alchol) on thermoinactivation of proteins, circular dichroism, solution viscosity, and the solubility of reduced and S‐carboxy‐methylated lysozyme indicated that amphiphilic PEG and PVP inhibit intermolecular collision of thermally denatured proteins by preferential interaction with thermally denatured proteins, resulting in the inhibition of intermolecular disulfide exchange. These findings regarding the different mechanisms of the effects of amphiphilic polymers––PEG and PVP––and Arg would expand the capabilities of methods to improve the chemical stability of proteins in solution. Biotechnol. Bioeng. 2012; 109: 2543–2552. © 2012 Wiley Periodicals, Inc.
Effect of Time in Chemical Cleaning of Ultrafiltration Membranes
Authors: Levitsky I. , Naim R. , Duek A. , Gitis V. 
Published: April 2012

AbstractChemical cleaning of ultrafiltration membranes is often considered successful when the flux through a cleaned membrane is much higher than through a pristine one. Here, a novel definition of cleaning intensity is proposed as the product of the concentration of the cleaning agent and the cleaning time (Ct), and it is shown that Ct values between 0.5 and 1.0 g h L–1 are sufficient for effective cleaning. Experiments with PES‐30 and PVDF‐30 membranes fouled by bovine serum albumin and cleaned with surfactant, oxidant, and formulated cleaning agents demonstrate that a good cleaning should last for 10–20 min and restore the flux through a virgin membrane. More intensive cleaning increases the membrane hydrophilicity and the water flux, but soon causes more severe fouling and even membrane disintegration.
Synthesis of PCP‐Supported Nickel Complexes and their Reactivity with Carbon Dioxide
Authors: Schmeier Timothy J. , Nova Ainara , Hazari Nilay , Maseras Feliu 
Published: April 2012

AbstractThe Ni amide and hydroxide complexes [(PCP)Ni(NH2)] (2; PCP=bis‐2,6‐di‐tert‐butylphosphinomethylbenzene) and [(PCP)Ni(OH)] (3) were prepared by treatment of [(PCP)NiCl] (1) with NaNH2 or NaOH, respectively. The conditions for the formation of 3 from 1 and NaOH were harsh (2 weeks in THF at reflux) and a more facile synthetic route involved protonation of 2 with H2O, to generate 3 and ammonia. Similarly the basic amide in 2 was protonated with a variety of other weak acids to form the complexes [(PCP)Ni(2‐Me‐imidazole)] (4), [(PCP)Ni(dimethylmalonate)] (5), [(PCP)Ni(oxazole)] (6), and [(PCP)Ni(CCPh)] (7), respectively. The hydroxide compound 3, could also be used as a Ni precursor and treatment of 3 with TMSCN (TMS=trimethylsilyl) or TMSN3 generated [(PCP)Ni(CN)] (8) or [(PCP)Ni(N3)] (9), respectively. Compounds 3–7, and 9 were characterized by X‐ray crystallography. Although 3, 4, 6, 7, and 9 are all four‐coordinate complexes with a square‐planar geometry around Ni, 5 is a pseudo‐five‐coordinate complex, with the dimethylmalonate ligand coordinated in an X‐type fashion through one oxygen atom, and weakly as an L‐type ligand through another oxygen atom. Complexes 2–9 were all reacted with carbon dioxide. Compounds 2–4 underwent facile reaction at low temperature to form the κ1‐O carboxylate products [(PCP)Ni{OC(O)NH2}] (10), [(PCP)Ni{OC(O)OH}] (11), and [(PCP)Ni{OC(O)‐2‐Me‐imidazole}] (12), respectively. Compounds 10 and 11 were characterized by X‐ray crystallography. No reaction was observed between 5–9 and carbon dioxide, even at elevated temperatures. DFT calculations were performed to model the thermodynamics for the insertion of carbon dioxide into 2–9 to form a κ1‐O carboxylate product and understand the pathways for carbon dioxide insertion into 2, 3, 6, and 7. The computed free energies indicate that carbon dioxide insertion into 2 and 3 is thermodynamically favorable, insertion into 8 and 9 is significantly uphill, insertion into 5 and 7 is slightly uphill, and insertion into 4 and 6 is close to thermoneutral. The pathway for insertion into 2 and 3 has a low barrier and involves nucleophilic attack of the nitrogen or oxygen lone pair on electrophilic carbon dioxide. A related stepwise pathway is calculated for 7, but in this case the carbon of the alkyne is significantly less nucleophilic and as a result, the barrier for carbon dioxide insertion is high. In contrast, carbon dioxide insertion into 6 involves a single concerted step that has a high barrier.
Saccharide‐Modified Nanodiamond Conjugates for the Efficient Detection and Removal of Pathogenic Bacteria
Authors: Hartmann Mirja , Betz Patrick , Sun Yuchen , Gorb Stanislav N. , Lindhorst Thisbe K. , Krueger Anke 
Published: April 2012

AbstractThe detection and removal of bacteria, such as E. coli in aqueous environments by using safe and readily available means is of high importance. Here we report on the synthesis of nanodiamonds (ND) covalently modified with specific carbohydrates (glyco–ND) for the precipitation of type 1 fimbriated uropathogenic E. coli in solution by mechanically stable agglutination. The surface of the diamond nanoparticles was modified by using a Diels–Alder reaction followed by the covalent grafting of the respective glycosides. The resulting glyco–ND samples are fully dispersible in aqueous media and show a surface loading of typically 0.1 mmol g−1. To probe the adhesive properties of various ND samples we have developed a new sandwich assay employing layers of two bacterial strains in an array format. Agglutination experiments in solution were used to distinguish unspecific interactions of glyco–ND with bacteria from specific ones. Two types of precipitates in solution were observed and characterized in detail by light and electron microscopy. Only by specific interactions mechanically stable agglutinates were formed. Bacteria could be removed from water by filtration of these stable agglutinates through 10 μm pore‐size filters and the ND conjugate could eventually be recovered by addition of the appropriate carbohydrate. The application of glycosylated ND allows versatile and facile detection of bacteria and their efficient removal by using an environmentally and biomedically benign material.
ChemInform Abstract: Noncentrosymmetric Inorganic Open‐Framework Chalcohalides with Strong Middle IR SHG and Red Emission: Ba3AGa5Se10Cl2 (A: Cs, Rb, K).
Authors: Yu Peng , Zhou Liu‐Jiang , Chen Ling 
Published: April 2012

AbstractThe title compounds are synthesized by solid state reactions of Ba, Ga, Se, MCl (M: Cs, Rb, K), and BaCl2 in the ratio 5:10:20:2:1 (850 °C, 100 h).
ChemInform Abstract: Structural Requirements in Lithium Cobalt Oxides for the Catalytic Oxidation of Water.
Authors: Gardner Graeme P. , Go Yong Bok , Robinson David M. , Smith Paul F. , Hadermann Joke , Abakumov Artem , Greenblatt Martha , Dismukes G. Charles 
Published: April 2012

AbstractTwo polymorphs of nanocrystalline lithium cobalt oxides, cubic spinel Li2Co2O4 and rhombohedral layered LiCoO2 are examined for their application in the photocatalytic oxidation of water.
ChemInform Abstract: One Unprecedented 1‐D Europium Thioindate‐thioantimonate Based on Heterometallic Mixed Nitro‐Thioclusters with Photoluminescent Properties.
Authors: Zhou Jian , An Litao , Liu Xing , Zou Huahong , Hu Feilong , Liu Chaomin 
Published: April 2012

Abstract{[Eu(tepa)]2 [μ2‐SbS3](μ2‐H2O)} [Eu(tepa)In4S9]·0.25tepa (tepa: tetraethylenepentamine) is solvothermally synthesized from a mixture of In, S, Sb, Eu2O3, and tepa (autoclave, 170 °C, 8 d, 65% yield).
ChemInform Abstract: ThSi2 Type Ytterbium Disilicide and Its Analogues YbTxSi2‐x (T: Cr, Fe, Co).
Authors: Peter Sebastian C. , Kanatzidis Mercouri G. 
Published: April 2012

AbstractSingle crystals of the title compounds are prepared from the elements in liquid indium (alumina crucible, 1000 °C, 5 h).
ChemInform Abstract: The Polygallides: Yb3Ga7Ge3 and YbGa4Ge2.
Authors: Peter Sebastian C. , Malliakas Christos D. , Nakotte Heinze , Kothapilli Karunakar , Rayaprol Sudhindra , Schultz Arthur J. , Kanatzidis Mercouri G. 
Published: April 2012

AbstractThe new title compounds are synthesized in excess liquid Ga from mixtures of Yb, Pd, Ga, and Ge in the atomic ratio 3:2:30:6 (alumina crucible in an evacuated silica tube, 1123 K, 48 h).
ChemInform Abstract: Li2Sr4Al2Ta2N8O, a Nitridoalumotantalate with BCT‐Zeolite Type Structure.
Authors: Pust Philipp , Schnick Wolfgang 
Published: April 2012

AbstractThe title compound is synthesized from Li3AlN2, Sr(NH2)2, LiN3, and Li as a flux (wall reaction with the Ta crucible, 900 °C, 24 h).
ChemInform Abstract: Doped Semimetal Clusters: Ternary, Intermetalloid Anions [Ln@Sn7Bi7]4‐ and [Ln@Sn4Bi9]4‐ (Ln: La, Ce) with Adjustable Magnetic Properties.
Authors: Lips Felicitas , Holynska Malgorzata , Clerac Rodolphe , Linne Uwe , Schellenberg Inga , Poettgen Rainer , Weigend Florian , Dehnen Stefanie 
Published: April 2012

AbstractCompounds (III) are characterized by single crystal XRD, electrospray ionization mass spectrometry, Moessbauer spectroscopy, magnetic measurements, and quantum chemical DFT calculations.
ChemInform Abstract: Polyoxometalates Paneling Through {Mo2O2S2} Coordination: Cation‐Directed Conformations and Chemistry of a Supramolecular Hexameric Scaffold.
Authors: Marrot Jerome , Pilette Marie Anne , Haouas Mohamed , Floquet Sebastien , Taulelle Francis , Lopez Xavier , Poblet Josep M. , Cadot Emmanuel 
Published: April 2012

AbstractDepending on the ionic strength and the nature of alkali cations, trivacant [AsW9O33]9‐ polyoxometalate ions (POM) and [Mo2O2S2]2+ cations (L) react to form hexameric [(POM)6L9]36‐, tetrameric [(POM)4L6]24‐, and dimeric [(POM)2L3]12‐ clusters.
ChemInform Abstract: Time‐Resolved Self‐Assembly of a Fullerene‐Topology Core—Shell Cluster Containing 68 Uranyl Polyhedra.
Authors: Qiu Jie , Ling Jie , Sui Audrey , Szymanowski Jennifer E. S. , Simonetti Antonio , Burns Peter C. 
Published: April 2012

Abstract(K,Na)44 [(UO2)68(O2)74(OH)16 (NO3)16 (H2O)16]·nH2O is synthesized from aqueous solutions containing UO2(NO3)2, H2O2, Me4NOH, malonic acid, NaCl, and KCl (air, pH 11.2, 25 °C, 30 d; about 16% yield).
ChemInform Abstract: The Thioantimonate Anion SbS33‐ Acting as Ligand: Syntheses, Crystal Structures and Selected Properties of [Mn(1,2‐chxn)2SbS3H] and [Cr(1,3‐dap)2SbS3].
Authors: Seidlhofer B. , Spetzler V. , Naether C. , Bensch W. 
Published: April 2012

AbstractCompounds (IV) and (VII) are solvothermally synthesized and their structures are determined by single crystal XRD.
ChemInform Abstract: A Polyoxometalate‐Based Single‐Molecule Magnet with an S = 21/2 Ground State.
Authors: Fang Xikui , Koegerler Paul , Speldrich Manfred , Schilder Helmut , Luban Marshall 
Published: April 2012

AbstractCompound (III) crystallizes in the space group P$\bar 1$ with Z = 1.
ChemInform Abstract: Non‐Prussian Blue Structures and Magnetic Ordering of Na2MnII[MnII(CN)6] and Na2MnII [MnII(CN)6]·2H2O.
Authors: Kareis Christopher M. , Lapidus Saul H. , Her Jae‐Hyuk , Stephens Peter W. , Miller Joel S. 
Published: April 2012

AbstractNa2Mn[Mn(CN)6]·2H2O (I) is prepared from aqueous solutions of Mn(OAc)2 and NaCN (80% yield).
ChemInform Abstract: Mono Thiomalonates as Thioester Enolate Equivalents—Enantioselective 1,4‐Addition Reactions to Nitroolefins under Mild Conditions.
Authors: Clerici Paolo , Wennemers Helma 
Published: April 2012

AbstractCinchona alkaloid derived thiourea CIN is a highly enantioselective organocatalyst for the title reaction of monothiomalonate (I) bearing an acid labile Pmb ester and an acid stable p‐methoxyphenyl thioester group.
ChemInform Abstract: Design, Synthesis, and Applications of Potential Substitutes of t‐Bu‐Phosphinooxazoline in Pd‐Catalyzed Asymmetric Transformations and Their Use for the Improvement of the Enantioselectivity in the Pd‐Catalyzed Allylation Reaction of Fluorinated Allyl Enol Carbonates.
Authors: Belanger Etienne , Pouliot Marie‐France , Courtemanche Marc‐Andre , Paquin Jean‐Francois 
Published: April 2012

AbstractA number of new and readily available phosphinooxazoline derivatives is prepared.
ChemInform Abstract: Reaction of InCl3 with Various Reducing Agents: InCl3—NaBH4‐Mediated Reduction of Aromatic and Aliphatic Nitriles to Primary Amines.
Authors: Saavedra Jaime Z. , Resendez Angel , Rovira Alexander , Eagon Scott , Haddenham Dustin , Singaram Bakthan 
Published: April 2012

AbstractNitriles containing halide moieties undergo tandem reduction giving dehalogenated amines such as (IV).
ChemInform Abstract: AlMe3‐Promoted Formation of Amides from Acids and Amines.
Authors: Li Jianqing , Subramaniam Krishnananthan , Smith Daniel , Qiao Jennifer X. , Li Jie Jack , Qian‐Cutrone Jingfang , Kadow John F. , Vite Gregory D. , Chen Bang‐Chi 
Published: April 2012

AbstractA wide range of amines can be coupled with carboxylic acids via a dimethylaluminum intermediate.
ChemInform Abstract: Nucleophilic Ring‐Opening Reaction of Benzoxazinones —Access to o‐Amino‐2,2,2‐trifluoroacetophenones.
Authors: Allendoerfer Nadine , Es‐Sayed Mazen , Nieger Martin , Braese Stefan 
Published: April 2012

AbstractStarting from commercially available anthranilic acid derivatives, a new short synthesis of the title compounds (V) is described.
ChemInform Abstract: A Phosphine‐Free Pd Catalyst for the Selective Double Carbonylation of Aryl Iodides.
Authors: de la Fuente Veronica , Godard Cyril , Zangrando Ennio , Claver Carmen , Castillon Sergio 
Published: April 2012

AbstractA general and practical method for the synthesis of the compounds (IV) and (VI) is presented.
ChemInform Abstract: Isoquinoline‐Catalyzed Addition of 2‐Bromo‐1‐aryl‐1‐ethanone to Dialkyl Azodicarboxylate: Synthesis of Trialkyl 2‐[(1E)‐N‐(Alkoxycarbonyl)‐2‐aryl‐2‐oxoethanehydrazonoyl] hydrazine‐1,1,2‐tricarboxylate.
Authors: Kianmehr Ebrahim , Bakhtiary Alireza , Zhu Chengjian 
Published: April 2012

AbstractThe products are purified by crystallization.
ChemInform Abstract: Cyclic Aromatic Analogues of the Hendrickson Reagent; NMR Studies and Electrophilic Properties.
Authors: Moussa Ziad 
Published: April 2012

AbstractA mild and rapid method for the synthesis of the compounds (II) is presented by using a new ′POP′ reagent, which is prepared in situ from 1,2‐bis(diphenylphosphino)benzene and Tf2O.
ChemInform Abstract: Direct Guanidinylation of Aryl and Heteroaryl Halides via Copper‐Catalyzed Cross‐Coupling Reaction.
Authors: Hammoud Hassan , Schmitt Martine , Bihel Frederic , Antheaume Cyril , Bourguignon Jean‐Jacques 
Published: April 2012

AbstractThe reaction of some o‐diiodo‐ and o‐dibromobenzenes is possible which provides a new approach to 2‐aminobenzimidazoles.
ChemInform Abstract: Heck Arylation of Styrenes Promoted by an Air‐Stable Phosphinito Complex with Palladium(II); Synthesis of Resveratrol.
Authors: Morales‐Serna Jose Antonio , Zuniga‐Martinez Armando , Salmon Manuel , Gavino Ruben , Cardenas Jorge 
Published: April 2012

AbstractA highly efficient catalyst in the chemo‐, regio‐, and stereoselective synthesis of the stilbenes (III) and resveratrol (VI) is presented.
ChemInform Abstract: Efficient Enantioselective Michael Addition of Nitroalkenes Catalyzed by a Surfactant‐Type Bifunctional Thiourea Organocatalyst in the Presence of Water.
Authors: Li Jian , Liu Yang , Liu Li 
Published: April 2012

AbstractA new chiral surfactant‐type bifunctional thiourea catalyst is developed which efficiently promotes the asymmetric Michael reaction of nitroalkenes (II) with ketones.
ChemInform Abstract: Simple Palladium‐Catalyzed C—N Bond Formation for Poor Nucleophilicity of Aminonaphthalenes.
Authors: Shue Yi‐Jen , Yang Shyh‐Chyun 
Published: April 2012

AbstractThe reaction of various aminonaphthalenes and phenothiazine with allyl acetate is first investigated and then extended to 1‐aminonaphthalene and different types of allylic acetate substrates.
ChemInform Abstract: Copper‐Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organolithium Reagents.
Authors: Bos Pieter H. , Rudolph Alena , Perez Manuel , Fananas‐Mastral Martin , Harutyunyan Syuzanna R. , Feringa Ben L. 
Published: April 2012

AbstractA highly regio‐, enantio‐, and anti‐selective procedure for the synthesis of the compounds (III) is presented.
ChemInform Abstract: A Convenient Synthesis of Polysubstituted 2‐Amino‐4,5‐dihydrofuran‐3‐nitriles from Benzoins or Benzaldehydes.
Authors: Du Ding , Hu Zhongyuan , Tang Weifang , Wang Bo , Lu Tao 
Published: April 2012

AbstractBase‐promoted cyclocondensation between benzoins and arylidenemalononitriles constitutes a direct synthesis of highly functionalized dihydrofurans.
ChemInform Abstract: Synthesis of 2‐(Polyfluoroaryl)benzofurans via a Copper(I)‐Catalyzed Reaction of 2‐(2,2‐Dibromovinyl)phenol with Polyfluoroarene.
Authors: Ye Shengqing , Liu Gang , Pu Shouzhi , Wu Jie 
Published: April 2012

AbstractThe novel and efficient process allows the preparation of various target compounds which are of interest in medicinal and material chemistry.
ChemInform Abstract: A Highly Efficient Large‐Scale Asymmetric Michael Addition of Isobutyraldehyde to Maleimides Promoted by a Novel Multifunctional Thiourea.
Authors: Ma Zhi‐wei , Liu Yu‐xia , Li Pan‐li , Ren Hang , Zhu Yu , Tao Jing‐chao 
Published: April 2012

AbstractThe new chiral thiourea TUC bearing a chiral lipophilic beyerane scaffold and a primary amino group, catalyzes the asymmetric Michael addition between aliphatic aldehydes and different maleimides (I) with only 0.5 mol % loading.
ChemInform Abstract: One‐Pot Cascade Approach to 1,3′‐Bipyrrole Derivatives from Trisubstituted Olefins with Tosylmethyl‐isocyanide (TosMIC).
Authors: Qiu Fangli , Wu Jianwei , Zhang Yaohong , Hu Miao , Yu Yongping 
Published: April 2012

AbstractThe title process affords directly the bipyrroles (III), a skeleton present in natural products such as marinopyrrole A and B, with concomitant loss of R1‐OH and ‐CO‐R3.
ChemInform Abstract: A Highly Efficient Transacetalization of 2‐Formylpyrrole Acetals in Alkaline Media.
Authors: Yan Zhao Hua , Kang Run Hua , Liu Yong Jie , Lin Sen 
Published: April 2012

AbstractTransacetalization of nitrogen‐unprotected 2‐formylpyrrole acetals with sodium alkoxides provides the target products in nearly quantitative yields.
ChemInform Abstract: Facile Synthesis of N‐(Arylsulfonyl) ‐4‐ethoxy‐5‐oxo‐2,5‐dihydro‐1H‐pyrrole‐2,3‐dicarboxylates by One‐Pot Three‐Component Reaction.
Authors: Anaraki‐Ardakani Hossein , Noei Maziar , Tabarzad Afrooz 
Published: April 2012

AbstractThe title compounds (IV) represent structural units of heterocyclic natural products.
ChemInform Abstract: Palladium‐Catalyzed Cascade Cyclization of Ynamides to Azabicycles.
Authors: Greenaway Rebecca L. , Campbell Craig D. , Holton Oliver T. , Russell C. Adam , Anderson Edward A. 
Published: April 2012

AbstractBromoenynamides can serve as substrates for the synthesis of a diverse range of bicyclic aminodienes using a palladium cascade cyclization.
ChemInform Abstract: A Direct Copper‐Catalyzed Route to Pyrrolo‐Fused Heterocycles from Boronic Acids.
Authors: Beveridge Ramsay E. , Gerstenberger Brian S. 
Published: April 2012

AbstractA one‐pot two‐step process is developed which can be applied to the synthesis of various pyrrolo‐fused N‐heterocyclic systems.
ChemInform Abstract: Synthesis of 4‐Hydroxy‐2‐oxazolidinones Catalyzed by Tin Alkoxides.
Authors: Kojima Ryota , Sawamoto Satoshi , Okamura Aritomo , Takahashi Hiroki , Tsunoi Shinji , Shibata Ikuya 
Published: April 2012

AbstractTitle compounds are synthesized by reaction of α‐hydroxy ketones with aliphatic as well as aromatic isocyanates (II) in the presence of a tin alkoxide catalyst either under conventional heating or microwave irradiation.
ChemInform Abstract: Palladium‐Catalyzed Direct Arylation of Pyridine N‐Oxide with 2‐Bromoacetanilides. Synthesis of Benzisoxazolo[2,3‐a]pyridinium Tetrafluoroborates.
Authors: Myers Jeffery T. , Hanna James M. Jr. 
Published: April 2012

AbstractA short synthesis of title compounds (IV) is achieved by regioselective Pd‐catalyzed direct C—H arylation of pyridine N‐oxide and subsequent cyclization via hydrolysis, diazotation, and intramolecular substitution of dinitrogen.
ChemInform Abstract: Synthesis and Anticancer Activity of Indolin‐2‐one Derivatives Bearing the 4‐Thiazolidinone Moiety.
Authors: Wang Shuobing , Zhao Yanfang , Zhu Wufu , Liu Ying , Guo Kaixing , Gong Ping 
Published: April 2012

AbstractA novel series of the title indolinone derivatives (IX) (16 examples) is synthesized and evaluated in vitro for its cytotoxicity against three human cancer cell lines.
ChemInform Abstract: Aerobic Visible‐Light Photoredox Radical C—H Functionalization: Catalytic Synthesis of 2‐Substituted Benzothiazoles.
Authors: Cheng Yannan , Yang Jun , Qu Yue , Li Pixu 
Published: April 2012

AbstractInstead in the presence of a household CFL light, the reaction can also be carried out under sunlight although with somewhat lower yields.
ChemInform Abstract: CuO‐Promoted Construction of N‐2‐Aryl‐Substituted‐1,2,3‐triazoles via Azide—Chalcone Oxidative Cycloaddition and Post Triazole Arylation.
Authors: Zhang Yuanqing , Li Xiaolong , Li Jihui , Chen Jinying , Meng Xu , Zhao Mingming , Chen Baohua 
Published: April 2012

AbstractThe regioselective process is successful with various aryl fluorides and with the chloride (IVb).
ChemInform Abstract: Formal [4 + 2] Cycloaddition of Cyclobutanones Bearing Alkyne—Cobalt Complex at Their 3‐Positions.
Authors: Kawano Mizuki , Kiuchi Takaaki , Matsuo Jun‐ichi , Ishibashi Hiroyuki 
Published: April 2012

AbstractThe title reaction is highly efficient in the presence of aldehydes and produces cis‐ substituted pyrans with excellent selectivity.
ChemInform Abstract: DABCO‐Catalyzed Regioselective Cyclization Reactions of β,γ‐Unsaturated α‐Ketophosphonates or β,γ‐Unsaturated α‐Ketoesters with Allenic Esters.
Authors: Pei Cheng‐Kui , Wu Lei , Lian Zhong , Shi Min 
Published: April 2012

AbstractKetophosphonates (I) afford mainly dihydropyran derivatives, whereas ketoesters (V) give predominantly highly functionalized tetrahydropyran derivatives.