bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of retroauricular keloids: Revision of cases treated at the ENT service of HC/UFPR
Authors: Ballin Annelyse Cristine , Becker Renata Vecentin , Ribeiro Talita Beithum , Cavichiolo Juliana Benthien , Ballin Carlos Roberto , Mocellin Marcos , Carvalho Bettina 
Published: May 2012

Summary
Introduction: Keloids are benign tumors arising from abnormal healing of the skin, and there are several procedures available for their treatment.
Objective: The objective of this study was to evaluate the outcomes of patients undergoing treatment of keloids after ear, nose, and throat (ENT) surgeries at our service center.
Method: We conducted thorough, retrospective and prospective analysis of records of patients undergoing treatment of retroauricular keloids at our center.
Results: Nine patients were evaluated, and 6 underwent resection and adjuvant beta-therapy, 2 underwent resection with local application of corticosteroids, and only 1 underwent resection without adjuvant therapy. There was no recurrence of keloids in patients that were treated with beta-therapy in the early postoperative period. One patient had relapsed despite corticosteroid administration and late beta-therapy.
Discussion: Several techniques have been used for the treatment of retroauricular keloids, and beta-therapy is thought to yield the best results, followed by the use of intralesional corticosteroids.
Conclusion: Treatment of retroauricular keloids remains a challenge. While new techniques are being developed, resection followed by early beta-therapy is still the best treatment option.
Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua
Authors: Kiyamu Melisa , Bigham Abigail , Parra Esteban , León‐Velarde Fabiola , Rivera‐Chira María , Brutsaert Tom D. 
Published: May 2012

AbstractHigh altitude natives have enlarged vital capacities and residual volumes (RV). Because pulmonary volumes are an indication of functionally relevant traits, such as diffusion capacity, the understanding of the factors (genetic/developmental) that influence lung volumes provides insight into the adaptive responses of highlanders. In order to test for the effect of growth and development at high altitude on lung volumes, we obtained forced vital capacities (FVC), RV, and total lung capacities (TLC) for a sample of 65 Peruvian females of mostly Quechua origins (18–34 years) who were sub‐divided into two well‐matched groups: 1) sea‐level born and raised females (BSL, n = 34) from Lima, Peru (150 m), and 2) high‐altitude born and raised females (BHA, n = 31) from Cerro de Pasco, Peru (4,338 m). To determine Quechua origins, Native American ancestry proportion (NAAP) for each individual was assessed using a panel of 70 ancestry informative markers. NAAP was similar between groups (BSL = 91.71%; BHA = 89.93%; P = 0.240), and the analysis confirmed predominantly Quechua origins. After adjusting for body size and NAAP, BHA females had significantly higher FVC (3.79 ± 0.06 l; P < 0.001), RV (0.98 ± 0.03 l; P < 0.001) and TLC (4.80 ± 0.07 l; P < 0.001) compared to BSL females (FVC = 3.33 ± 0.05 l; RV = 0.69 ± 0.03 l; TLC = 4.02 ± 0.06 l). NAAP was not associated with FVC (P = 0.352) or TLC (P = 0.506). However, NAAP was positively associated with RV (P = 0.004). In summary, results indicate that developmental exposure to high altitude in females constitutes an important factor for all lung volumes, whereas both genetic and developmental factors seem to be important for RV. Am J Phys Anthropol 2012. © 2012 Wiley Periodicals, Inc.
Melt‐spun polylactic acid fibers: Effect of cellulose nanowhiskers on processing and properties
Authors: John Maya Jacob , Anandjiwala Rajesh , Oksman Kristiina , Mathew Aji P 
Published: May 2012

AbstractBio‐based continuous fibers were processed from polylactic acid (PLA) and cellulose nanowhiskers (CNWs) by melt spinning. Melt compounding of master batches of PLA with 10 wt % CNWs and pure PLA was carried out using a twin‐screw extruder in which compounded pellets containing 1 and 3 wt % of CNWs were generated for subsequent melt spinning. The microscopy studies showed that the fiber diameters were in the range of 90‐95 µm, and an increased surface roughness and aggregations in the fibers containing CNWs could be detected. The addition of the CNWs restricted the drawability of the fibers to a factor of 2 and did not affect the fiber stiffness or strength, but resulted in a significantly lower strain and slightly increased crystallinity. Furthermore, CNWs increased the thermal stability, creep resistance and reduction in thermal shrinkage of PLA fibers, possibly indicating a restriction of the polymer chain mobility due to the nanoscale additives. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
A generalized approach to stabilization of linear interconnected time‐delay systems
Authors: Mahmoud Magdi S. , Xia Yuanqing 
Published: May 2012

AbstractThe objective of this paper is to propose a generalized approach to stabilization of systems which are composed of linear time‐delay subsystems coupled by linear time‐varying interconnections. The proposed algorithms, which are formulated within the convex optimization framework, provide decentralized solutions to the problem of delay‐dependent asymptotic stability with strict dissipativity. It is established that the new methodology can reproduce earlier results on passivity, positive realness and disturbance attenuation. Then a decentralized structure of dissipative state‐feedback controllers is designed to render the closed‐loop interconnected system delay‐dependent asymptotically stable with strict dissipativity. Numerical examples are presented to illustrate the applicability of the design method.Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Accuracy of imaging for predicting operative approach in Crohn's disease
Authors: Malgras B , Soyer P , Boudiaf M , Pocard M , Lavergne-Slove A , Marteau P , Valleur P , Pautrat K 
Published: May 2012

Abstract

Background
The aim of this study was to assess the accuracy of preoperative imaging in detecting the extent of disease and predicting the operative approach in patients with Crohn's disease.

Methods
Patients with Crohn's disease who were scheduled to undergo operation were evaluated before operation using computed tomography enteroclysis (CTE) and magnetic resonance enterography (MRE). Preoperative imaging findings were correlated with intraoperative and pathological findings to estimate the capabilities of preoperative imaging in detecting lesions due to Crohn's disease. The operative approach determined before surgery was compared with the procedure actually performed, which was based on intraoperative findings.

Results
Fifty-two patients with Crohn's disease were studied; 26 were evaluated before surgery with CTE and 26 with MRE. Eighty-nine lesions due to Crohn's disease were confirmed surgically (60 small bowel stenoses, 21 fistulas and 8 abscesses). CTE confirmed the presence of 38 of 41 lesions (sensitivity 93 per cent) and MRE 48 of 48 lesions (sensitivity 100 per cent); a correct estimation of the disease with an exact prediction of the operative approach was obtained in 49 (94 per cent) of 52 patients. Discrepant findings between preoperative imaging and operative findings were observed in three patients (6 per cent), who had CTE.

Conclusion
Preoperative imaging using CTE or MRE is highly accurate for assessing Crohn's disease lesions before operation, allowing correct prediction of the operative approach.
Characterization of New Class III Lantibiotics—Erythreapeptin, Avermipeptin and Griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus Demonstrates Stepwise N‐Terminal Leader Processing
Authors: Völler Ginka H. , Krawczyk Joanna M. , Pesic Alexander , Krawczyk Bartlomiej , Nachtigall Jonny , Süssmuth Roderich D. 
Published: May 2012

AbstractLantibiotics are a large group of ribosomally synthesized peptides post‐translationally modified to incorporate the amino acid lanthionine. They are classified, according to their biosynthetic pathway and bioactivity, into three major subtypes. Of Actinomycetes type III lantibiotics, only four peptides (SapB, SapT, LabA1, and LabA2) have been described and structurally characterized, although homologous gene clusters are abundant in other Actinomycetes. All these gene clusters share a similar architecture with a characteristic Ser/Ser/Cys motif in precursor peptides, which has previously been suggested to act as a precursor for lanthionine (SapB) and labionin (LabA2) rings. Mass spectrometry screening led to the discovery and characterization of three new representatives of type III lantibiotics: Avermipeptin (Avi), Erythreapeptin (Ery), and Griseopeptin (Gri) from Streptomyces avermitilis DSM 46492, Saccharopolyspora erythraea NRRL 2338, and Streptomyces griseus DSM 40236, respectively. Apart from the assignment of these peptides to their corresponding gene clusters, additional investigations on Avi, Ery and Gri peptides indicate stepwise leader processing by putative aminopeptidase‐like protease(s), thus yielding mixtures of differently N‐terminal‐processed lantibiotic peptides. Similar peptide processing was observed for a heterologously expressed eryth biosynthetic gene cluster expressed in a Streptomyces host system. Remarkably, all isolates of the new type III lantibiotics contain both the amino acids lanthionine and labionin, thus implying dual‐mode cyclase activity of the processing lyase‐kinase‐cyclase enzymes. These findings have implications for the structures and maturation of other type III lantibiotics from Actinomycetes.
European registry of carotid artery stenting: Results from a prospective registry of eight high volume EUROPEAN institutions
Authors: Stabile Eugenio , Garg Pallav , Cremonesi Alberto , Bosiers Marc , Reimers Bernhard , Setacci Carlo , Cao Piergiorgio , Schmidt Andrej , Sievert Horst , Peeters Patrick , Nikas Dimitry , Werner Martin , de Donato Gianmarco , Parlani Giambattista , Castriota Fausto , Hornung Marius , Mauri Laura , Rubino Paolo 
Published: May 2012

AbstractBackgroundCarotid endarterectomy (CEA) is the standard revascularization therapy to prevent stroke in patients with carotid artery disease. Carotid artery stenting (CAS) could be considered a potential alternative in patients at high surgical risk. Recent clinical trials have challenged this concept due a relatively high incidence of post‐CAS adverse events, which occurred in low volume centers. The aim of this study was to evaluate the outcomes associated with neuroprotected CAS in selected high volume centers.MethodsFrom January 2007 to December 2007, 1,611 patients underwent neuroprotected CAS in eight European Centers. For each patients, clinical, procedural, and one month follow‐up data from all patients have been collected. An independent clinical events committee adjudicated the events.ResultsOverall in hospital death was 0.06% (one patient), whereas in‐hospital stroke was 0.49% (eight patients). Between hospital discharge and 30 days three additional patients died (0.18%) and 10 patients experienced a stroke (0.67%). Overall 30 days mortality was 0.24% (four patients) and stroke incidence 1.12% (18 patients). The 30 day stroke/death rate was 1.36%.ConclusionsCAS is a reasonable alternative to CEA to treat carotid artery atherosclerosis in well‐experienced high volume centers. These data suggest that future prospective trials comparing CAS and CEA outcomes should include only centers highly experienced in both treatment modalities. © 2012 Wiley Periodicals, Inc.
Implementation of the Finite Element Method for Simulation of Mass Transfer in Membrane Contactors
Authors: Shirazian S. , Pishnamazi M. , Rezakazemi M. , Nouri A. , Jafari M. , Noroozi S. , Marjani A. 
Published: May 2012

AbstractMathematical modeling and numerical simulation of gas separation by means of polymeric membrane contactors is presented. The finite element method is implemented for numerical simulation. COMSOL Multiphysics is used for simulation. Continuity equations are solved via computational fluid dynamics techniques based on the finite element method. A laminar velocity profile is applied for the solvent. Velocity distribution of the gas flow in the contactor is obtained by Happel's model. The predictions of percent CO2 removal obtained by the modeling were compared with the experimental values from literature for CO2 removal from CO2/N2 gas mixtures with amines. The modeling predictions were in good agreement with experimental data for different values of liquid flow rates.
Palladium‐Catalyzed Aerobic Intermolecular Cyclization of Acrylic Acid with 1‐Octene to Afford α‐Methylene‐γ‐butyrolactones: The Remarkable Effect of Continuous Water Removal from the Reaction Mixture and Analysis of the Reaction by Kinetic, ESI‐MS, and XAFS Measurements
Authors: Miyoshi Yasuyuki , Akatsuka Takeo , Okuoka Shin‐ichi , Tsukajima Aki , Makino Mitsuaki , Saito Makoto , Yonehara Koji 
Published: May 2012

AbstractFurther study of our aerobic intermolecular cyclization of acrylic acid with 1‐octene to afford α‐methylene‐γ‐butyrolactones, catalyzed by the Pd(OCOCF3)2/Cu(OAc)2⋅H2O system, has clarified that the accumulation of water generated from oxygen during the reaction causes deactivation of the Cu cocatalyst. This prevents regeneration of the active Pd catalyst and, thus, has a harmful influence on the progress of the cyclization. As a result, both the substrate conversion and product yield are efficiently improved by continuous removal of water from the reaction mixture. Detailed analysis of the kinetic and spectroscopic measurements performed under the condition of continuous water removal demonstrates that the cyclization proceeds in four steps: 1) equilibrium coordination of 1‐octene to the Pd acrylate species, 2) Markovnikov‐type acryloxy palladation of 1‐octene (1,2‐addition), 3) intramolecular carbopalladation, and 4) β‐hydride elimination. Byproduct 2‐acryloxy‐1‐octene is formed by β‐hydride elimination after step 2). These cyclization steps fit the Michaelis–Menten equation well and β‐hydride elimination is considered to be a rate‐limiting step in the formation of the products. Spectroscopic data agree sufficiently with the existence of the intermediates bearing acrylate (PdO bond), η3‐C8H15 (PdC bond), or C11H19O2 (PdC bond) moieties on the Pd center as the resting‐state compounds. Furthermore, not only CuII, but also CuI, species are observed during the reaction time of 2–8 h when the reaction proceeds efficiently. This result suggests that the CuII species is partially reduced to the CuI species when the active Pd catalytic species are regenerated.
ChemInform Abstract: Hydrothermal Synthesis of Lutetium Disilicate Nanoparticles.
Authors: Tang Xiaoping , Gao Yanfeng , Chen Hongfei , Luo Hongjie 
Published: May 2012

AbstractIrregular‐ and rod‐shaped Lu2Si2O7 powders with particle sizes ranging from 71 to 340 nm are prepared by hydrothermal reaction of Lu2O3 and Na2SiO3 in aqueous HNO3 solutions (autoclave, pH 4—10, 230—260 °C, 4—12 h).
ChemInform Abstract: Synthesis and Characterization of Th2N2(NH) Isomorphous to Th2N3.
Authors: Silva G. W. Chinthaka , Yeamans Charles B. , Weck Philippe F. , Hunn John D. , Cerefice Gary S. , Sattelberger Alfred P. , Czerwinski Ken R. 
Published: May 2012

AbstractThe title compound is synthesized by reaction of (NH4)4ThF8 (obtained by solid state reaction of ThO2 and NH4HF2), ThF4, or ThNF with LiNH2 under flowing NH3 at a temperature ≥800 °C.
ChemInform Abstract: Catalytic Enantioselective 1,2‐Diboration of 1,3‐Dienes: Versatile Reagents for Stereoselective Allylation.
Authors: Kliman Laura T. , Mlynarski Scott N. , Ferris Grace E. , Morken James P. 
Published: May 2012

AbstractFunctionalized homoallylic alcohol products are synthesized via enantioselective 1,2‐diboration of 1,3‐dienes.
ChemInform Abstract: Alkyne‐Acetal Cyclization Reactions Mediated by Formic Acid; 3‐Acylated ‐2,5‐dihydrofurans and Related Oxygen and Nitrogen Heterocycles.
Authors: Cuthbertson James D. , Godfrey Andrew A. , Unsworth William P. , Taylor Richard J. K. 
Published: May 2012

AbstractA variety of partially reduced heterocycles is easily prepared by cyclization of alkynyl acetals in formic acid.
ChemInform Abstract: Application of Flow Chemistry to the Selective Reduction of Esters to Aldehydes.
Authors: Munoz Juan de M. , Alcazar Jesus , de la Hoz Antonio , Diaz‐Ortiz Angel 
Published: May 2012

AbstractAromatic, heteroaromatic as well as aliphatic esters are reduced to the aldehydes by LiAlH(iBu)2(OtBu) in the presence of different functional groups under flow conditions.
ChemInform Abstract: Synthesis of Aryl Alkynyl Carboxylic Acids and Aryl Alkynes from Propiolic Acid and Aryl Halides by Site‐Selective Coupling and Decarboxylation.
Authors: Park Kyungho , Palani Thiruvengadam , Pyo Ayoung , Lee Sunwoo 
Published: May 2012

AbstractCoupling of aryl iodides with propiolic acid is carried out under conditions A) at 50°C to produce the corresponding aryl alkynyl carboxylic acids.
ChemInform Abstract: A Phosphine‐Free Heterogeneous Suzuki—Miyaura Reaction of Aryl Bromides Catalyzed by MCM‐41‐Supported Tridentate Nitrogen Palladium Complex under Air.
Authors: Zhao Hong , Ding Guodong , Xu Li , Cai Mingzhong 
Published: May 2012

AbstractThe Pd complex is efficiently used as heterogeneous recyclable catalyst for a high‐yielding preparation of biaryls.
ChemInform Abstract: Intramolecular SN′‐Type Aromatic Substitution of Benzylic Carbonates at Their para‐Position.
Authors: Ueno Satoshi , Komiya Sadakazu , Tanaka Takeshi , Kuwano Ryoichi 
Published: May 2012

AbstractCyclization of benzylic carbonates with an active methine connected to the o‐phenylene tether at the meta‐position leads to 3‐methyl‐9,10‐dihydrophenanthrenes [cf.
ChemInform Abstract: Nitrogen‐ and Phosphorus‐Containing Lewis Base Catalyzed [4 + 2] and [3 + 2] Annulation Reactions of Isatins with But‐3‐yn‐2‐one.
Authors: Lian Zhong , Shi Min 
Published: May 2012

AbstractDABCO‐mediated [4 + 2] cycloaddition of indolediones (I) with butynone (II) provides access towards spiro(indoline‐pyran) diones (III) in high yields.
ChemInform Abstract: Reactivity of N‐Alkylthiiranimines Toward Simple Nucleophiles and Iso(thio)cyanates.
Authors: Nimmesgern Hildegard , Schaumann Ernst , Adiwidjaja Gunadi 
Published: May 2012

AbstractThe hydrolysis of thiiranimines (I) in the presence of TFA leads to amides (III), whilst similar reaction with hydrochloric acid gives rise to chlorides (II).
ChemInform Abstract: RuCl3·3H2O Catalyzed Tandem Reaction of Alkynylbromides with 2‐Aminothiophenols in Water: A Convenient Synthesis of 2‐Benzoylbenzothiazoles.
Authors: Fan Xuesen , He Yan , Guo Shenghai , Zhang Xinying 
Published: May 2012

AbstractThe reaction is applicable to various aryl alkynyl bromides and 2‐aminothiophenols.
ChemInform Abstract: Synthesis of 6‐Hydroxyisochromenes and 6‐Hydroxyisocoumarins from 3‐Ethoxycyclohex‐2‐en‐1‐one.
Authors: Majetich George , Grove Jeremy L. 
Published: May 2012

Abstract6‐Hydroxyisochromene (VII) and 6‐hydroxyisocoumarin (VIII) are synthesized via a novel intramolecular hydroalkoxylation reaction of alcohol (V).
ChemInform Abstract: An Improved Synthesis of Functionalized cis‐Decahydroquinolines Using a Baylis—Hillman‐Type Adduct.
Authors: Huang Junfeng , Petersen Jeffrey , Bergmeier Stephen C. 
Published: May 2012

Abstractcis‐Decahydroquinolines are obtained via the Baylis—Hillman type intermediate (III).
ChemInform Abstract: Synthesis and Anticonvulsant Evaluation of Some New 2,3,8‐Trisubstituted‐4(3H)‐quinazoline Derivatives.
Authors: El‐Azab Adel S. , ElTahir Kamal E. H. 
Published: May 2012

AbstractA series of title compounds is prepared using (IV) as one of the key intermediates.
ChemInform Abstract: Directing Group Controlled Hydrosilylation: Regioselective Functionalization of Alkyne.
Authors: Kawasaki Yuuya , Ishikawa Youhei , Igawa Kazunobu , Tomooka Katsuhiko 
Published: May 2012

AbstractThe hydrosilylation of (homo)propargylic alcohols proceeds regioselectively affording a single silylalkene.
ChemInform Abstract: A New Derivative of Galanthamine: Methylene Insertion into the Aromatic Ring in Place of Cyclopropanation.
Authors: Keglevich Peter , Kovacs Peter , Hazai Laszlo , Santa Zsuzsanna , Dubrovay Zsofia , Hada Viktor , Szantay Csaba Jr. , Kalaus Gyoergy , Szantay Csaba 
Published: May 2012

AbstractIn the course of the reaction between galanthamine (I) and diazomethane, methylene insertion into the aromatic ring is observed instead of the expected cyclopropanation of the C—C double bond.
The vaccine uptake research gap in low‐ and middle‐income countries: Commentary on ‘Interventions for improving coverage of child immunization in low‐ and middle‐income countries’
Authors: MacDonald Noni E. , Smith Jennifer , Graven Michael 
Published: May 2012

AbstractThis is a commentary of Cochrane review, published in this issue of EBCH, first published as: Oyo‐Ita A, Nwachukwu CE, Oringanje C, Meremikwu MM. Interventions for improving coverage of child immunization in low‐ and middle‐income countries. Cochrane Database of Systematic Reviews 2011, Issue 7. Art. No.: CD008145. DOI: 10.1002/14651858.CD008145.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Summary article. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Commentary on ‘Sublingual immunotherapy for treating allergic conjunctivitis’
Authors: Hughes Jenny 
Published: May 2012

AbstractThis is a commentary of Cochrane review, published in this issue of EBCH, first published as: Calderon MA, Penagos M, Sheikh A, Canonica GW, Durham S. Sublingual immunotherapy for treating allergic conjunctivitis. Cochrane Database of Systematic Reviews 2011, Issue 7. Art. No.: CD007685. DOI: 10.1002/14651858.CD007685.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Summary article. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration
Commentary on: ‘Pacifiers use in term infants and breastfeeding: caution with the Cochrane results’
Authors: Binns Colin , Lee Seung Wook 
Published: May 2012

AbstractThis is a commentary of Cochrane review, published in this issue of EBCH, first published as: Jaafar SH, Jahanfar S, Angolkar M, Ho JJ. Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding. Cochrane Database of Systematic Reviews 2011, Issue 3. Art. No.: CD007202. DOI: 10.1002/14651858.CD007202.pub2.Further information for this Cochrane review is available in this issue of EBCH in the accompanying Summary article. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. The Cochrane Collaboration