bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Interstitial Nephritis and Oxalate Nephropathy After Rapid Pasireotide Response in Treatment-resistant Acromegaly
Authors: Hayes Annabelle G , Penny Mark J , Aivazian Karina , Greenfield Jerry R 
Published: May 2024

Abstract
We report a case of interstitial nephritis, likely secondary to oxalate nephropathy, due to the development of pancreatic exocrine dysfunction after commencement of pasireotide for acromegaly. Pasireotide is known to impair insulin secretion but can also impair pancreatic exocrine function, hypothezised to result from high-affinity binding of somatostatin receptors 1, 2, 3, and 5. This has been an advantage in postoperative tissue anastomoses after pancreatic surgery, but exocrine insufficiency has not been reported when used for the treatment of acromegaly. A 73-year-old woman, diagnosed with acromegaly, was unable to achieve biochemical control despite 2 surgical resections of an invasive mammosomatotroph pituitary tumor and treatment with cabergoline and maximal-dose lanreotide. The tumor expressed somatostatin receptor type 5 but not somatostatin receptor type 2, predicting good response from pasireotide, which was commenced at 40 mg every 4 weeks. IGF-1 rapidly normalized, but the patient presented with nausea, anorexia, and acute kidney injury. Renal biopsy revealed acute-on-chronic interstitial nephritis, with numerous oxalate crystals. Increased fecal fat globules were noted on fat stain (3+), supporting malabsorption as an etiology of secondary enteric hyperoxaluria. Renal function recovered to near baseline over months following pasireotide withdrawal and high-dose glucocorticoids.
Hyperandrogenism and Hypokalemic Thyrotoxic Periodic Paralysis in a North American Adolescent Girl
Authors: Gladding Anne , Bartoletti Joseph , Iyer Pallavi , Dabrowski Elizabeth 
Published: May 2024

Abstract
We present a unique case of hypokalemic thyrotoxic periodic paralysis (TPP) in an adolescent girl in North America. TPP is a rare but dangerous complication seen in thyrotoxic patients characterized by hypokalemia and acute proximal symmetric lower-extremity weakness. It is an especially rare phenomenon in pediatrics, with roughly 20 case reports described in adolescents worldwide; the majority are male. Our patient is a 14-year-old Asian girl with biochemical hyperandrogenism and known Graves disease who presented with an acute episode of lower-extremity weakness after eating a carbohydrate-rich meal. Laboratory workup revealed hypokalemia, hypomagnesemia, an undetectable thyrotropin, and hyperthyroxinemia. Electrolyte derangements responded well to supplementation, and the muscle weakness resolved with electrolyte normalization. Following improvement in thyroid function, the patient underwent thyroidectomy for definitive management of Graves disease. As TPP is potentially exacerbated by higher androgen and insulin levels, we suspect that with increasing rates of obesity and polycystic ovary syndrome, the incidence of TPP among adolescents may increase. It is therefore critically important that there is awareness and recognition of this serious diagnosis among all health care providers.
The role of enhanced expression of Cx43 in patients with ulcerative colitis
Authors: Liu Weidong , Feng Yan , Li Ting , Shi Tian , Hui Wenjia , Liu Huan , Gao Feng 
Published: May 2024

Abstract
The pathogenesis of ulcerative colitis (UC) involves chronic inflammation of the submucosal layer and disruption of epithelial barrier function within the gastrointestinal tract. Connexin 43 (Cx43) has been implicated in the pathogenesis of intestinal inflammation and its associated carcinogenic effects. However, a comprehensive analysis of Cx43’s role in mucosal and peripheral immunity in patients with UC is lacking. In this study, the colon tissues of patients with UC exhibited severe damage to the intestinal mucosal barrier, resulting in a significant impairment of junctional communication as observed by transmission electron microscopy. The mRNA expression of Cx43 was found to be significantly elevated in the UC group compared to the control group, as determined using the Affymetrix expression profile chip and subsequently validated using qRT-PCR. The immunofluorescence analysis revealed a significantly higher mean fluorescence intensity of Cx43 in the UC group compared to the control group. Additionally, Cx43 was observed in both the cell membrane and nucleus, providing clear evidence of nuclear translocation. The proportion of Cx43 in the UC group for CD4+ and CD8+ T lymphocytes was increased in the control group, but only the proportion of Cx43 for CD8+ T lymphocytes showed significant difference by flow cytometry. The involvement of Cx43 in the pathogenesis of UC and its potential role in mucosal immunity warrants further investigation, as it holds promise as a prospective biomarker and therapeutic target for this condition. The proportion of Cx43 in the UC group for CD4+ and CD8+ T lymphocytes was increased in the control group, but only the proportion of Cx43 for CD8+ T lymphocytes showed a significant difference.
Frequency down-conversion of terahertz waves at optically induced temporal boundaries in GaAs waveguides
Authors: Takano Keisuke , Uchiyama Satoko , Nagase Shintaro , Tsuchimoto Yuka , Nakanishi Toshihiro , Nakata Yosuke , Pérez-Urquizo Joel , Madéo Julien , Dani Keshav M. , Miyamaru Fumiaki 
Published: May 2024

Abstract
In this study, the frequency down-conversion of terahertz waves is analytically and experimentally demonstrated at the temporal boundaries within a GaAs waveguide. The temporal boundary is established by photoexciting the top surface of the waveguide, thereby instantaneously increasing its electrical conductivity. This photoexcited waveguide supports a transverse electromagnetic (TEM) mode with a frequency lower than those of the transverse magnetic (TM) modes present in the original waveguide. At the temporal boundary, the incident TM mode couples with the TEM mode, resulting in frequency down-conversion. Subtracting the propagation loss from the frequency-converted components indicates that the frequency conversion occurs with an efficiency consistent with the analytical predictions. The propagation loss is primarily due to ohmic loss, caused by the finite electrical conductivity of the photoexcited region. Given that the frequency of transverse electric modes is up-converted at the temporal boundary, our findings suggest that the direction of frequency conversion (upward or downward) can be controlled by manipulating the incident polarization. The polarization-dependent frequency conversion in waveguides holds significant potential for applications in devices designed for the interconversion of terahertz signals across various frequency channels. This capability is instrumental in the development of frequency-division-multiplexed terahertz wave communication systems, thereby enabling high data transfer rates.
Ready to bleed when touched – Moral Injury in the Special Operations Forces military population
Authors: Gielas Anna M. 
Published: May 2024

Abstract
The armed forces combine different military populations with specific patterns of psycho-medical challenges and needs. The Special Operations Forces (SOF) exhibit one such pattern because they undergo more rigorous selection procedures, train differently and generally engage in different types of missions than other military populations. The aim of this commentary is to briefly introduce the psycho-medical patterns of SOF while paying particular attention to the growing discussion of Moral Injury (MI) in this military population. The mental health construct of MI refers to the persistent psycho-social harm resulting from exposure to events that clash with an individual’s moral beliefs. So far, research has focused on causes and symptoms of MI, less on prevention strategies and early intervention opportunities. This article advocates making a regular screening for symptoms of MI an element of routine physical check-ups of SOF to identify MI-related problems earlier and destigmatise mental health struggles, thereby countering severe manifestations of MI and alleviating suicidality rates in the SOF military population.
Foam concrete for lightweight construction applications: A comprehensive review of the research development and material characteristics
Authors: Liu Yajun , Zhao Zhilong , Amin Muhammad Nasir , Ahmed Bilal , Khan Kaffayatullah , Arifeen Siyab Ul , Althoey Fadi 
Published: May 2024

Abstract
Foam concrete or foamcrete is a lightweight, porous material with a wide range of applications in the construction domain. This article focused on reviewing porosity, thermal conductivity, acoustic properties, compressive strength (f
c′), elastic modulus (E), flexural strength (f
y), stability, resistance to hostile environments, density, and fire resistance of foam concrete. A systematic literature analysis was conducted to identify relevant research trends on foam concrete. The challenges and limitations of foam concrete research were highlighted, including the lack of standardized testing methods and the need for more research on the long-term durability and structural performance of foam concrete. The analysis of the literature data revealed that there had been a growing interest in foamcrete research over the past decade. Foam concrete may be utilized in several construction applications due to its adaptability and wide range of uses. Its potential uses can be increased by developing new manufacturing methods and the inclusion of certain admixtures. The present research has the potential to be advantageous for scholars interested in collaborative advancement and the exchange of novel tactics and concepts, owing to the visual and statistical representation of the regions/countries and researchers that have contributed.
Industrie 4.0: Die Revolution geht weiter
Authors: Müller Stefan 
Published: May 2024

Abstract
The vision of Industry 4.0 describes a fundamental transformation of production and logistics. A study shows that after more than 10 years of hype, no company has reached its goal. The relevance remains high and often the basics are still being worked on. Even if increasing competitive pressure makes changes necessary, a lack of resources is the main hurdle. Real change can only succeed if the smart factory is a management priority.
Low-Code/No-Code zur Darstellung von Produktionsdaten über die Asset Administration Shell
Authors: Serwa Kamila 
Published: May 2024

Abstract
In order to drive digital transformation in manufacturing companies, low-code/no-code offers an alternative approach to software development. The technical article shows the functionality and application of the low-code/ no-code method in production in combination with the Digital Twin and the Asset Administration Shell. Using the open source platform „Saltcorn“, it is described how a dashboard for visualizing production data can be implemented in the form of a web application using low-code/ no-code without any programming knowledge. Companies can use dashboards to analyze their production data, for example to make decisions to optimize production.
Humanzentrierte Implementierung von (teil-)autonomen Drohnen
Authors: Vogel Olga , Kluge Annette 
Published: May 2024

Abstract
The industrial use of drones is constantly increasing due to the transition from Industry 4.0 to Industry 5.0. A prerequisite for the concrete implementation is the legal and organizational risk assessment of flight robotics. The core of the article is a systematic overview of relevant human-centered risk factors for the adaptation of drones in organizations. Based on the proposed risk taxonomy, design options for human-drone interaction and an overview of key questions for risk assessment are presented.
Gestaltung eines wertstromübergreifenden Performance-Management-Systems
Authors: Longard Lukas , Wang Yuxi , Herz Oliver , Metternich Joachim 
Published: May 2024

Abstract
KPI systems for evaluating and improving industrial processes are often used ineffectively in production companies, mostly due to arbitrarily selected KPIs and an overemphasis on financial aspects. Existing performance management approaches only describe basic elements and offer few practical recommendations. Implementation is usually only carried out by upper and middle management and neglects integration into production. This article presents a methodology that derives KPIs from corporate objectives in order to identify precise deviations and support data-driven analyses. The method is illustrated by evaluating the example of a process-accurate recording of throughput time.
Machine Learning for the Model Prediction of Final Semester Assessment (FSA) using the Multiple Linear Regression Method
Authors: Rachmawati Fitria , Jaenudin Jejen , Ginting Novita Br , Laksono Panji 
Published: May 2024

Corona virus (COVID-19) is the reason behind the collapse of the National Assembly. The first is the Final Semester Assessment (FSA) , which is a component of the student's graduation. The aforementioned evaluation process is a crucial consideration for the teacher since it uses several intricate surveys and mark components. A prediction model is employed to assist teachers in providing suitable results for student learning. The method that is used is called the multiple linear regression. This multiple linear regression algorithm yields an accuracy level of approximately 92%. The analysis results using the method are used as a guide to understanding student’s index. This index is a rating that appears based on the Minimum Credit Count (MCC). Therefore, the goal of this study is to determine students' understanding of the FSA prediction value, which will be taken into consideration through the results of the MCC weights in the form of a range in the form of "Grade." Additionally, the research aims to determine the accuracy of the results from the model obtained using multiple linear regression algorithms in predicting students' FSA.
Intratubular Penetration Depth of Ultrasound Activated Bioceramic Sealant Cements at the Dentin-Radicular Cement Interface
Authors: Jara Castro Marisa , Terán Casafranca Liliana , Valdez-Jurado Freddy Ronald , Pineda Martha , Salcedo-Moncada Doris , Mayta-Tovalino Frank 
Published: May 2024

To evaluate the intratubular penetration depth of ultrasound-activated bioceramic sealant cements into root dentin, specifically at the dentin-cement interface. This in vitro experimental study was conducted with samples that were randomly divided based on the type of sealer used and whether ultrasound activation was applied prior to obturation. This resulted in four experimental groups (n=40). Groups A1 and B1 utilized the Eighteeth Ultra X ultrasonic activator with a blue tip #20 featuring a 2% taper at low power for activation, while groups A2 and B2 did not employ any form of activation. The symbol (+) denotes groups with ultrasonic activation, while (-) represents groups without ultrasonic activation. In the middle third, it was observed that BioC Sealer (+) had a mean sealing value of 0.66±0.17, while MTA Fillapex (+) showed a mean value of 0.38±0.07. It was found that BioC Sealer (-) had a mean sealing value of 0.24±0.04 in the middle third, while MTA Fillapex (-) showed a mean value of 0.16±0.04. These differences were not statistically significant (p=0.569). In the apical third, the BioC Sealer (-) presented a mean sealing value of 0.44±0.17, while the MTA Fillapex (-) obtained a mean value of 0.30±0.04. However, this difference did not reach statistical significance (p=0.0745), suggesting that both materials can provide a similar seal in the apical third. The results suggest that both BioC Sealer and MTA Fillapex provide a comparable seal in the middle and apical thirds of the root canal system, however, this was not statistically significant. This indicates their potential efficacy in both endodontic sealing procedures.
MANEL BELLMUNT SERRANO AND JOAN MAHIQUES CLIMENT, EDS. Literature, Science & Religion. Textual Transmission and Translation in Medieval and Early Modern Europe. Kassel: Edition Reichenberger, 2020. 466 pp.
Authors: Marfany Marta 
Published: May 2024

Reseña de Literature, Science & Religion. Textual Transmission and Translation in Medieval and Early Modern Europe de Manel Bellmunt Serrano y Joan Mahiques Climent (eds.).
ANA MARÍA LAGUNA AND JOHN BEUSTERIEN, EDS. Goodbye Eros: Recasting Forms and Norms of Love in the Age of Cervantes. Toronto: U of Toronto P, 2020. 281 pp.
Authors: Pasero Anne 
Published: May 2024

Reseña de Goodbye Eros: Recasting Forms and Norms of Love in the Age of Cervantes de Ana María Laguna y John Beusterien (eds.).
N. MICHELLE MURRAY. Home Away from Home: Immigrant Narratives, Domesticity, and Coloniality in Contemporary Spanish Culture. Chapel Hill: U of North Carolina P, 2018. 226 pp.
Authors: Coleman Jeffrey K. 
Published: May 2024

Reseña de Home Away from Home: Immigrant Narratives, Domesticity, and Coloniality in Contemporary Spanish Culture de N. Michelle Murray.
NIALL H. D. GERAGHTY. The Polyphonic Machine: Capitalism, Political Violence, & Resistance in Contemporary Argentine Literature. U of Pittsburgh P, 2018. 304 pp.
Authors: Sharman Adam 
Published: May 2024

Reseña de The Polyphonic Machine: Capitalism, Political Violence, & Resistance in Contemporary Argentine Literature de Niall H. D. Geraghty.
CARRIE L. RUIZ AND ELENA RODRIGUEZ-GURIDI, EDS. Shipwreck in the Early Modern Hispanic World. Fwd. Josiah Blackmore. Lewisburg: Bucknell UP 2022. viii + 164 pp.
Authors: Martínez-Osorio Emiro 
Published: May 2024

Reseña de Shipwreck in the Early Modern Hispanic World. Foreword by Josiah Blackmore de Carrie L. Ruiz y Elena Rodriguez-Guridi (eds.).
Humeral Component Version Has No Effect on Outcomes Following Reverse Total Shoulder Arthroplasty
Authors: Wiater J. Michael , Lee James Y.J. , Shields Edward J.W. , Childers Karen , Dery Lauren , Koueiter Denise 
Published: May 2024

Background:
Controversy exists regarding the ideal humeral component version to optimize humeral rotation and patient outcomes in reverse total shoulder arthroplasty (rTSA).

Methods:
Patients undergoing primary rTSA for rotator cuff tear arthropathy, a massive rotator cuff tear, or primary osteoarthritis with a rotator cuff tear were randomized to placement of the humeral component in neutral version or 30° of retroversion. Shoulder active range of motion and strength and visual analog scale (VAS) pain, American Shoulder and Elbow Surgeons (ASES), and Patient-Reported Outcomes Measurement Information System Global 10 (PROMIS-10) scores were collected up to 2 years postoperatively. The goal of the study was to determine whether humeral external rotation and internal rotation are affected by humeral component version following rTSA at 2 years postoperatively.

Results:
Sixty-six patients were included in the analysis. The median follow-up was 26 months for the neutral and 27 months for the 30° retroversion group. No differences between the groups were observed with respect to the primary diagnosis, sex, age, body mass index, or American Society of Anesthesiologists (ASA) class. The 2 groups did not differ significantly in terms of improvement at 2 years in active shoulder abduction (p = 0.969), forward elevation (p = 1.000), internal rotation measured as the highest spinal level reached (p = 1.000), internal rotation with the arm abducted 90° (p = 0.451), external rotation (p = 0.362), or muscle strength in forward elevation (p = 1.000), abduction (p = 1.000), external rotation (p = 0.617), or internal rotation (p = 1.000). The 2 groups did not differ significantly in terms of improvement in postoperative ASES (p = 1.000), PROMIS-10 physical (p = 1.000), or VAS pain scores (p = 0.718) at the time of final follow-up. In the neutral version group, 1 patient underwent revision for instability and 1 for stiffness. One acromial stress fracture occurred in the 30° humeral retroversion group. Scapular notching was observed in 7 (21.2%) of the patients in neutral version group and 5 (15.2%) of the patients in the 30° retroversion group (p = 0.750).

Conclusions:
Securing the humeral component at neutral version or 30° of retroversion in rTSA resulted in similar active shoulder external rotation, internal rotation, forward elevation, abduction, and strength measurements, complication rates, and VAS pain, PROMIS-10 physical, and ASES scores at 2 years postoperatively.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Transiliac-Shortening Osteotomy to Treat Ischial Pressure Injury due to Fixed Pelvic Obliquity
Authors: Schwend Richard M. , Nguyen Brandon T. , Noe McKenna C. , Anderson John T. , Jiang Shao 
Published: May 2024

Case:
A 17-year-old adolescent boy with Gross Motor Function Classification System 5 cerebral palsy and neuromuscular scoliosis underwent posterior spinal fusion and segmental spinal instrumentation from T3 to the pelvis. He developed a right ischial pressure injury a few months postoperatively, which persisted despite nonoperative measures. He subsequently underwent an ipsilateral transiliac-shortening osteotomy 16 months after spinal surgery to treat his residual pelvic obliquity and the ischial pressure injury, which healed completely. At the 1-year follow-up visit, there were no further signs of pressure injury.

Conclusion:
This case report describes transiliac-shortening osteotomy as a viable treatment option for non-healing ischial pressure injuries secondary to fixed pelvic obliquity.
SLP Method Boosts Production Efficiency by 16% in Indonesia
Authors: Kusuma Dewi Fortuna , Cahyana Atikha Sidhi 
Published: May 2024

The study on improving the facility layout at CV. Surya Mega Yokasa demonstrated that the Systematic Layout Planning (SLP) method significantly enhances the efficiency of the production process, with a total reduction in material displacement distance by 13.45 meters and an efficiency increase of 16%. These findings imply that careful consideration of workflow and qualitative factors in layout planning can markedly optimize production flow and reduce congestion. However, the study did not factor in the Material Handling Costs (MHC), suggesting that future research should integrate MHC analysis to provide a more comprehensive evaluation of layout effectiveness and further optimize production efficiency.
Highlight:

Efficiency Boost: SLP reduced displacement by 13.45m, increasing efficiency by 16%.
Improved Workflow: SLP method improved production flow, reducing congestion.
Future Focus: Include Material Handling Costs for better layout evaluation.

Keywoard: Systematic Layout Planning, Blocplan, Production Efficiency, Material Flow, Facility Layout