bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marginal bone loss adjacent to conventional and immediate loaded two implants supporting a ball‐retained mandibular overdenture: a 3‐year randomized clinical trial
Authors: Elsyad Moustafa Abdou , Al‐Mahdy Yasmeen Fathy , Fouad Mohammed Mohammed 
Published: April 2011

Abstract
Objectives: The aim of this study was to evaluate and compare marginal bone loss and clinical outcomes of conventionally and immediately loaded two implants supporting a ball‐retained mandibular overdenture.
Materials and methods: Thirty six completely edentulous patients (22 males and 14 females) were randomly assigned into two groups. Each patient received two implants in the canine area of the mandible after a minimal flap reflection. Implants were loaded by mandibular overdentures either 3 months (conventional loading group) or the same day (immediate loading group) after implant placement. Ball attachments were used to retain all overdentures to the implants. Vertical and horizontal alveolar bone losses were evaluated in both groups 1 and 3 years after implant placement using multislice computed tomography, which allow evaluation of peri‐implant buccal and lingual alveolar bone. Plaque scores, gingival scores, probing depths and periotest values (PTVs) were evaluated at 4 months (baseline), 1 and 3 years after implant placement. Clinical and radiographic evaluations were performed at distal, labial, mesial and lingual peri‐implant sites.
Results: After 3 years of follow‐up period, the immediate loading group recorded significant vertical bone loss at distal and labial sites than the conventional loading group and no significant differences in horizontal bone loss between groups were observed. Probing depth at distal and labial sites in the immediate loading group were higher than the conventional loading group, while plaque scores, gingival scores and PTVs showed no significant differences between the two groups. A low level of positive correlation between plaque scores, gingival scores, probing depths and vertical bone loss was noted.
Conclusion: Immediately loaded two implants supporting a ball‐retained mandibular overdenture are associated with more marginal bone resorption and increased probing depths when compared with conventionally loaded implants after 3 years. The bone resorption and probing depths at distal and labial sites are significantly higher than those at mesial and lingual sites. Clinical outcomes do not differ significantly between loading protocols.
To cite this article: Elsyad MA, Al‐Mahdy YF, Fouad MM. Marginal bone loss adjacent to conventional and immediate loaded two implants supporting a ball‐retained mandibular overdenture: a 3‐year randomized clinical trial. Clin. Oral Impl. Res. 23, 23, 2012 496‐503. doi: 10.1111/j.1600‐0501.2011.02173.x
Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4‐ to 6‐year prospective study
Authors: De Santis Daniele , Trevisiol Lorenzo , D'Agostino Antonio , Cucchi Alessandro , De Gemmis Antonio , Nocini Pier Francesco 
Published: April 2011

Abstract
Introduction: Edentulism causes progressive bone resorption of the maxillae, which can lead to altered maxillo‐mandibular relationships. The aim of the study was to evaluate the applicability of guided bone regeneration (GBR) to Le Fort I osteotomies with interpositional bone grafts for treatment of patients with severe maxillary atrophy.
Materials and methods: Twenty consecutive patients characterized by severely atrophic maxillae were treated from January 2003 to January 2006 in order to resolve maxillary edentulism. All patients underwent pre‐prosthetic surgery, including a Le Fort I osteotomy associated with autologous interpositional bone grafts to move the alveolar arch forward and to resolve the maxillary atrophy. Barrier membranes were also used to cover the bone grafts and the osteotomy line, favoring the healing process according to GBR principles. Maxilla advancement and alveolar crest augmentation were measured to assess the degree of reconstruction. A total of 154 implants were inserted in reconstructed maxillae 4 months after surgery and were restored with fixed full‐arch dentures after another 4 months. Surgical and prosthetic complications were recorded and previously established implant success criteria were used to assess the success of this treatment protocol.
Results: The outcome of pre‐prosthetic surgery and implant‐supported rehabilitation was prospectively evaluated every year. All Le Fort I osteotomies were successfully carried out, with a mean maxilla advancement of 4.2 cm (range: 3.1–5 cm), which appeared to be stable during the follow‐up. After a mean follow‐up of 66.4±18.4 months, only four implants failed according to the success criteria, yielding a cumulative success rate of 95.8%.
Discussion and conclusions: Le Fort I osteotomies with the use of barrier membranes to cover the interpositional bone grafts can be a predictable treatment for edentulous patients with severely resorbed maxillae. The study data suggest that this approach makes it possible to compensate for both sagittal and vertical discrepancies due to maxilla atrophy, with a minimum resorption of advanced maxillae and grafted bone. A GBR‐based protocol seems to lead to high implant success rates, although further randomized controlled studies are needed to demonstrate the usefulness and advantageousness of GBR.
To cite this article: De Santis D, Trevisiol L, D'Agostino A, Cucchi A, De Gemmis A, Nocini PF. Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4‐ to 6‐year prospective study. Clin. Oral Impl. Res. 23, 2012; 60–69. doi: 10.1111/j.1600‐0501.2011.02181.x
A case of severe allergic reaction to cooked potato
Authors: Monti G , Viola S , Tarasco V , Lupica MM , Cosentino V , Castagno E 
Published: April 2011

AbstractWhite potato is a very common ingredient in the diet of infants in Mediterranean countries, and in its cooked form, it is one of the first solid foods introduced, usually around the age of 4–6 months. Allergy to potato is uncommon, and allergic reactions to cooked potato have been reported only in children. We report a case of severe potato‐induced allergic reaction in an 8‐month‐old infant with atopic dermatitis and multiple food allergies that raises questions about differential diagnosis between anaphylaxis and food protein‐induced enterocolitis syndrome (FPIES).Conclusion:  Allergy to cooked potatoes could be a cause of severe although rare allergic reactions; it could be very difficult, in some cases, to make a differential diagnosis between anaphylaxis and FPIES. Moreover, the diagnosis appears to be very important for the choice of therapy and long‐term allergologic management.
Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves
Authors: HASUNUMA Toshiya , KAWASHIMA Kenji , NAKAYAMA Hirofumi , MURAKAMI Toshiaki , KANAGAWA Hiroyuki , ISHII Takashige , AKIYAMA Kiyoshi , YASUDA Kenji , TERADA Fuminori , KUSHIBIKI Shiro 
Published: April 2011

ABSTRACTWe investigated the effect of cellooligosaccharide (CE) or a combination of dextran and Lactobacillus casei ssp. casei strain JCM1134T (synbiotic; SB) feeding on growth performance, fecal condition and hormone concentrations in Holstein calves. Fifty‐two female Holstein calves were randomly assigned to three treatment groups: CE feeding group (n = 16), SB feeding group (n = 18), and control group (n = 18). Body weight at 90 days of age, as well as daily body weight gain (DG) and feed efficiency after weaning to 90 days of age were greater (P < 0.05) in the CE feeding group than in the control group. The total fecal score tended to be lower (P < 0.1) in the SB feeding group than in the control group. Plasma insulin concentration was higher (P < 0.05) in the CE feeding group than in the control group at 90 days of age. Our results indicate that CE feeding improved DG and feed efficiency in calves. On the other hand, there was less effect on growth performance and fecal Escherichia coli counts in calves fed SB.
Effects of haul distance and stocking density on young suckling calves transported in Japan
Authors: UETAKE Katsuji , TANAKA Toshio , SATO Shusuke 
Published: April 2011

ABSTRACTWe conducted applicability evaluation of recommendations of the European Union (EU) and the Royal Society for Prevention of Cruelty to Animals (RSPCA) for suckling calves. Nineteen calves (14 Holstein aged 11–26 days and five cross‐bred aged 13–45 days) were divided into six groups. Three groups were allocated into the stocking densities of 0.25, 0.35, 0.45 m2/head and were weekly transported 50, 100, 150 km in this order. Another three groups were allocated and transported in reverse order. Observation was conducted during and after transportation. Blood sampling was performed before and after transportation. The occurrences of lying and turning round on the truck were significantly associated with stocking density (P < 0.05), but not with haul distance. Scratching was observed only in one calf. Incidence of watery feces was not associated with both factors. There were significant effects of haul distance on the concentrations of plasma cortisol and noradrenaline, and serum aspartate aminotranserase (AST) and IgM (P < 0.05). These concentrations, except cortisol, were higher after transportation at 150 km compared to the pre‐transportation value (AST and IgM P < 0.05; noradrenaline P < 0.10). Results suggest that haul distances greater than 100 km should not be recommended even for suckling calves transported in Japan.
Alleviation of body weight loss by dietary methionine is independent of insulin‐like growth factor‐I in protein‐starved young chickens
Authors: NAGAO Kenji , OKI Mai , TSUKADA Akira , KITA Kazumi 
Published: April 2011

ABSTRACTIt is well known that in protein‐starved chickens, small amounts of amino acid supplement, especially methionine, reduces nitrogen excretion and thereby improves nitrogen balance. On the other hand, excess intake of methionine causes growth depression and the growth‐depressive effect of excess methionine can be alleviated by consumption of dietary glycine. Insulin‐like growth factor‐I (IGF‐I) is one of various growth‐promoting factors relating to the efficiency of animal production and is known to be very sensitive to changes in nutritional status. In the present study, the interactive effect of glycine on nitrogen sparing effect of methionine in protein‐starved chickens was examined. In addition, the relation of IGF‐I and its specific binding protein to the nitrogen sparing effect of supplemented methionine was also investigated. Two‐days refeeding of methionine supplemented to protein‐free diet could promptly alleviate body weight loss in protein‐starved chickens, and the alleviation of body weight loss by methionine was not improved by glycine supplements. Moreover, such acute alleviation of body weight loss by dietary methionine was independent of the change in plasma IGF‐I concentration.
Mouse embryo co‐culture with autologous cumulus cells and fetal development post‐embryo transfer
Authors: OMAR FAROUK Farha Naomi , STOTT David , VLAD Marcela 
Published: April 2011

ABSTRACTThis study was conducted to examine the potential for implantation and sustainable fetal development of mouse embryos cultured from the pronuclear to blastocyst stage. Pronuclear embryos from ICR mice (Harlan Sprague‐Dawley) were cultured in Sydney IVF sequential media (Cook) to the blastocyst stage in medium only or co‐cultured with autologous cumulus cells. We also experimented with co‐culture in 100 µL drops. Drop co‐culture produced blastocyst formation rates with a mean of 47.0%, which was significantly higher (P < 0.05) compared to embryos cultured in identical culture conditions except without cumulus cells at 27.3%. Blastocysts obtained in vitro in Cook medium only and co‐cultured in Cook medium with cumulus cells were transferred to pseudopregnant females of ICR strain. The day of blastocyst transfer into surrogate females was designated as post‐transfer of blastocyst day 1 (PT 1). The implantation and fetal development was compared to embryo transfer of in vivo derived blastocysts, which served as controls. There were no statistical differences for implantation and fetal development rates for blastocysts cultured in vitro in either Cook medium only or co‐culture in Cook medium with cumulus cells compared to in vivo‐derived blastocysts. The advantage of the co‐culture system is in generating more blastocysts available for transfer.
Effects of high ambient temperature on urea‐nitrogen recycling in lactating dairy cows
Authors: OBITSU Taketo , KAMIYA Mitsuru , KAMIYA Yuko , TANAKA Masahito , SUGINO Toshihisa , TANIGUCHI Kohzo 
Published: April 2011

ABSTRACTEffects of exposure to hot environment on urea metabolism were studied in lactating Holstein cows. Four cows were fedad libituma total mixed ration and housed in a temperature‐controlled chamber at constant moderate (18°C) or high (28°C) ambient temperatures in a cross‐over design. Urea nitrogen (N) kinetics was measured by determining urea isotopomer in urine after single injection of [15N2]urea into the jugular vein. Both dry matter intake and milk yield were decreased under high ambient temperature. Intakes of total N and digestible N were decreased under high ambient temperature but urinary urea‐N excretion was increased. The ratio of urea‐N production to digestible N was increased, whereas the proportion of gut urea‐N entry to urea‐N production tended to be decreased under high ambient temperature. Neither return to the ornithine cycle, anabolic use nor fecal excretion of urea‐N recycled to the gut was affected by ambient temperature. Under high ambient temperature, renal clearance of plasma urea was not affected but the gut clearance was decreased. Increase of urea‐N production and reduction of gut urea‐N entry, in relative terms, were associated with increased urinary urea‐N excretion of lactating dairy cows in higher thermal environments.
DNA methylation analysis on satellite I region in blastocysts obtained from somatic cell cloned cattle
Authors: YAMANAKA Ken‐ichi , KANEDA Masahiro , INABA Yasushi , SAITO Koji , KUBOTA Kaiyu , SAKATANI Miki , SUGIMURA Satoshi , IMAI Kei , WATANABE Shinya , TAKAHASHI Masashi 
Published: April 2011

ABSTRACTMany observations have been made on cloned embryos and on adult clones by somatic cell nuclear transfer (SCNT), but it is still unclear whether the progeny of cloned animals is presenting normal epigenetic status. Here, in order to accumulate the information for evaluating the normality of cloned cattle, we analyzed the DNA methylation status on satellite I region in blastocysts obtained from cloned cattle. Embryos were produced by artificial insemination (AI) to non‐cloned or cloned dams using semen from non‐cloned or cloned sires. After 7 days of AI, embryos at blastocyst stage were collected by uterine flushing. The DNA methylation levels in embryos obtained by using semen and/or oocytes from cloned cattle were similar to those in in vivo embryos from non‐cloned cattle. In contrast, the DNA methylation levels in SCNT embryos were significantly higher (P < 0.01) than those in in vivo embryos from non‐cloned and cloned cattle, approximately similar to those in somatic cells used as donor cells. Thus, this study provides useful information that epigenetic status may be normal in the progeny of cloned cattle, suggesting the normality of germline cells in cloned cattle.
In vitro production of porcine embryos: current status, future perspectives and alternative applications
Authors: DANG‐NGUYEN Thanh Quang , SOMFAI Tamas , HARAGUCHI Seiki , KIKUCHI Kazuhiro , TAJIMA Atsushi , KANAI Yukio , NAGAI Takashi 
Published: April 2011

ABSTRACTThe pig is considered to be a suitable source of cells and organs for xenotransplants, as well as a transgenic animal to produce specific proteins, given the biological similarities it shares with human beings. However, the in vitro embryo production system in pigs is inefficient compared with those in other mammals, such as cattle or mice. Although numerous modifications have been applied to improve the efficiency of in vitro embryo production systems in pigs, not much progress has been made to overcome the problem of polyspermy, and low developmental ability due to insufficient cytoplasmic abilities of in vitro matured oocytes and improper culture conditions for the in vitro produced embryos. Recent achievements, such as the establishment of chemically defined medium and utilization of ‘zona hardening’ technique, have gained some success. However, further research for the reduction of polyspermy and detrimental effects of the culture systems in pigs is still needed.
Nautilin‐63, a novel acidic glycoprotein from the shell nacre of Nautilus macromphalus
Authors: Marie Benjamin , Zanella‐Cléon Isabelle , Corneillat Marion , Becchi Michel , Alcaraz Gérard , Plasseraud Laurent , Luquet Gilles , Marin Frédéric 
Published: April 2011

In molluscs, and more generally in metazoan organisms, the production of a calcified skeleton is a complex molecular process that is regulated by the secretion of an extracellular organic matrix. This matrix constitutes a cohesive and functional macromolecular assemblage, containing mainly proteins, glycoproteins and polysaccharides that, together, control the biomineral formation. These macromolecules interact with the extruded precursor mineral ions, mainly calcium and bicarbonate, to form complex organo‐mineral composites of well‐defined microstructures. For several reasons related to its remarkable mechanical properties and to its high value in jewelry, nacre is by far the most studied molluscan shell microstructure and constitutes a key model in biomineralization research. To understand the molecular mechanism that controls the formation of the shell nacreous layer, we have investigated the biochemistry of Nautilin‐63, one of the main nacre matrix proteins of the cephalopod Nautilus macromphalus. After purification of Nautilin‐63 by preparative electrophoresis, we demonstrate that this soluble protein is glycine‐aspartate‐rich, that it is highly glycosylated, that its sugar moieties are acidic, and that it is able to bind chitin in vitro. Interestingly, Nautilin‐63 strongly interacts with the morphology of CaCO3 crystals precipitated in vitro but, unexpectedly, it exhibits an extremely weak ability to inhibit in vitro the precipitation of CaCO3. The partial resolution of its amino acid sequence by de novo sequencing of its tryptic peptides indicates that Nautilin‐63 exhibits short collagenous‐like domains. Owing to specific polyclonal antibodies raised against the purified protein, Nautilin‐63 was immunolocalized mainly in the intertabular nacre matrix. In conclusion, Nautilin‐63 exhibits ‘hybrid’ biochemical properties that are found both in the soluble and insoluble proteins, rendering it difficult to classify according to the standard view on nacre proteins.Database
The protein sequences of N63 appear on the UniProt Knowledgebase under accession number P86702.
Nursing Diagnosis of Activity Intolerance: Clinical Validation in Patients With Refractory Angina
Authors: Rodrigues Clarissa Garcia , Moraes Maria Antonieta , Sauer Jaquelini Messer , Kalil Renato Abdala Karam , de Souza Emiliane Nogueira 
Published: April 2011

PURPOSE.  The study aims to clinically validate the defining characteristics (DCs) of the nursing diagnosis (ND) of Activity Intolerance for patients with ischemic heart disease and refractory angina.METHODS.  Cross‐sectional study was used, involving 22 patients with ND of Activity Intolerance. The Fehring method was used to validate the ND.FINDINGS.  Most DCs presented reliability indexes between 0.5 and 0.79. Three DCs presented reliability indexes ≥ 0.8.CONCLUSION.  All DCs were validated, and electrocardiographic changes indicating ischemia, verbal report of fatigue, and abnormal rate response to activity were considered as DC major.IMPLICATIONS FOR NURSING PRACTICE.  This study is relevant in daily nursing practice for guidance in establishing the care plan and describing the assistance for this group of patients.OBJETIVO.  Validar clinicamente as características definidoras (CD) do diagnóstico de enfermagem (DE) Intolerância à Atividade em pacientes cardiopatas isquêmicos com angina refratária.MÉTODOS.  Estudo transversal envolvendo 22 pacientes com DE Intolerância à Atividade. Método de Fehring foi utilizado para validação do DE.RESULTADOS.  A maioria das CD apresentaram taxa de fidedignidade entre 0.5–0.79. Três CD apresentaram índices de confiabilidade ≥ 0.8.CONCLUSÃO.  Todas as CD foram validadas, sendo que alterações eletrocardiográficas indicando isquemia, relato verbal de fadiga e resposta anormal da freqüência cardíaca à atividade foram validadas como CD maiores.IMPLICAÇÕES PARA A PRÁTICA DE ENFERMAGEM.  Este estudo é relevante na prática diária de enfermagem auxiliando no planejamento e orientação do plano de cuidados a esse grupo de pacientes.
Perimenstrual Syndrome: Nursing Diagnosis Among Taiwanese Nursing Students
Authors: Cheng Han‐Fu 
Published: April 2011

PURPOSE.  To determine the frequency and distribution of various perimenstrual symptoms experienced by Taiwanese nursing students.METHODS.  A descriptive “management of menstrual cramps survey” was utilized to collect information from 2,758 female nursing students in southern Taiwan.FINDINGS.  Of the participants, the most frequently reported perimenstrual symptom was a combination of four symptom categories, including mood change, pain, gastrointestinal disturbance, and functional ability decline.CONCLUSIONS.  A potentially new nursing diagnosis of perimenstrual syndrome including four symptom categories may be established.PRACTICE IMPLICATIONS.  The results are important for the education of healthcare professionals and the public. Understanding the interaction among perimenstrual symptoms may help guide nursing professionals in women's health care.
The α-effect in rotating convection: a comparison of numerical simulations
Authors: Hughes D. W. , Proctor M. R. E. , Cattaneo F. 
Published: April 2011

Abstract
Numerical simulations are an important tool in furthering our understanding of turbulent dynamo action, a process that occurs in a vast range of astrophysical bodies. It is important in all computational work that comparisons are made between different codes and, if non-trivial differences arise, that these are explained. In a recent paper, Käpylä, Korpi & Brandenburg describe an attempt to reproduce some of our results and, by employing a different methodology, they arrive at very different conclusions concerning the mean electromotive force and the generation of large-scale fields. Here we describe why the simulations of Käpylä et al. are simply not suitable for a meaningful comparison, since they solve different equations, at different parameter values and with different boundary conditions. Furthermore, we describe why the ‘resetting’ method adopted by Käpylä et al. to calculate the α-effect is inappropriate, since the resulting value of a cannot be related to the evolution of any large-scale magnetic field.