bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of physical fitness among people over 60 years of age
Authors: Ciesielski Jakub , Perkowski Radosław 
Published: June 2024

Introduction: An ageing of population is becoming more and more common. With age, the functionality and efficiency of the body decreases. As a result, the time spent by seniors on physical activity is shortened and physical fitness decreases. For this reason, the physical fitness of seniors should be regularly checked and they should be encouraged to take up physical activity. There are many proven and reliable tests used to assess physical fitness. Materials and methods: The study group consisted of 40 people (31 women and 9 men), aged 60-78 years. The tests used in following study were: the SPPB questionnaire, handgrip strength test, and arm and calf circumference measurements. An attempt was made to find sociodemographic factors that could influence the level of physical fitness. It was checked whether physical fitness and physical activity depend on age, gender and BMI. It was checked how much time older people spend on physical activity during the day and week. The study confirmed that physical fitness decreases with age. Results: Tests and interviews have shown that people who spend more than 60 minutes a day on physical activity achieve higher scores on the SPPB questionnaire. These results were applicable to both women and men. Studies in a larger and more diverse population would need to be repeated in order to further confirm these results and draw more conclusions.
Coordinating Charging Request Allocation Between Self-Interested Navigation Service Platforms
Authors: Guillet Marianne , Schiffer Maximilian 
Published: June 2024

Current electric vehicle market trends indicate an increasing adoption rate across several countries. To meet the expected growing charging demand, it is necessary to scale up the current charging infrastructure and to mitigate current reliability deficiencies, for example, due to broken connectors or misreported charging station availability status. However, even within a properly dimensioned charging infrastructure, a risk for local bottlenecks remains if several drivers cannot coordinate their charging station visit decisions. Here, navigation service platforms can optimally balance charging demand over available stations to reduce possible station visit conflicts and increase user satisfaction. Although such fleet-optimized charging station visit recommendations may alleviate local bottlenecks, they can also harm the system if self-interested navigation service platforms seek to maximize their own customers’ satisfaction. To study these dynamics, we model fleet-optimized charging station allocation as a resource allocation game in which navigation platforms constitute players and assign potentially free charging stations to drivers. We show that no pure Nash equilibrium guarantee exists for this game, which motivates us to study VCG mechanisms both in offline and online settings, to coordinate players’ strategies toward a better social outcome. Extensive numerical studies for the city of Berlin show that by coordinating players through VCG mechanisms, the social cost decreases on average by 42% in the online setting and by 52% in the offline setting. History: Accepted by David Alderson, Area Editor for Network Optimization: Algorithms & Applications. Supplemental Material: The online appendix is available at https://doi.org/10.1287/ijoc.2022.0269 .
Timing Is Everything: An Imprinting Framework for the Implications of Leader Emotional Expressions for Team Member Social Worth and Performance
Authors: Levitt Jacob S. , Coutifaris Constantinos G. V. , Green Paul I. , Barsade Sigal G. 
Published: June 2024

Leader emotional expressions have profound implications for team members. Research has established that how frequently leaders express positive and negative emotional expressions shapes team member performance through conveying critical social-functional information about team member social worth. Yet, this social-functional approach to emotions has not fully considered how the timing of leader emotional expressions during a team’s lifecycle can also shape the information conveyed to individual team members about their social worth. In this paper, we integrate the social-functional approach to emotions with imprinting theory to propose that the temporal context of leader emotional expressions has performance implications for individual team members through two distinct facets of social worth: respect and status. Specifically, our imprinting framework explains how positive leader emotional expressions during the early team phase have the most beneficial performance implications through imprinting respect in individual team members. We then propose that these positive implications are amplified by more-frequent-than-average negative leader emotional expressions during the midpoint phase. When filtered through earlier positive expressions, negative emotional expressions during the midpoint phase may signal opportunities for respect and status gains rather than respect and status losses. We find general support for our model in a preregistered four-wave longitudinal archival study of 9,968 team members on 234 consulting teams at a leading professional services company and a four-wave longitudinal field study at a NCAA Division 1 sports program including 245 student-athletes and 86 coaches on 20 varsity teams. Our work highlights that the temporal context of leader emotional expressions is an important performance predictor through social worth. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.17390 .
Magnetic resonance imaging scanning susceptibility weighted imaging sequences in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy
Authors: Zhao Hui , Wang Hai-Tao 
Published: June 2024

BACKGROUND
Magnetic resonance imaging (MRI) scanning with susceptibility weighted imaging (SWI) sequences plays a significant role in the diagnosis and prognostic evaluation of neonatal hypoxic-ischemic encephalopathy (HIE).
AIM
To observe the role of MRI multi-parameter quantitative indexes in the diagnosis of neonatal HIE.
METHODS
The imaging data from 23 cases of neonatal HIE admitted to the Imaging Department of Ganyu District People's Hospital of Lianyungang City and 23 neonates without HIE admitted during the same period were analyzed retrospectively from August, 2021 to December, 2023. The results of clinical judgment were compared with the results of computed tomography (CT) and MRI examinations.
RESULTS
The degree of cerebral edema (more than moderate), the number of damaged brain regions (> 2), the number of cerebral hemorrhages (> 2), and the percentage of small venous dilatation detected were higher in MRI than in CT examination, and the differences were statistically significant (P < 0.05). The total area of the largest region of cerebral damage and of cerebral hemorrhage observed by MRI examination were significantly larger than those of CT examination (P < 0.01). Multiparametric quantitative MRI combined with diffusion weighted imaging and SWI had higher sensitivity and accuracy than CT diagnosis, and the difference was statistically significant (P < 0.05). The difference in the specificity of the two modes of diagnosis was not significant (P > 0.05).
CONCLUSION
The use of MRI multi-parameter quantitative indexes can accurately diagnose and evaluate neonatal HIE.
Efficacy of acupoint injection in the treatment of chronic eczema and its influence on peripheral blood T cells
Authors: Gan Hui-Hui , Yang Gao , Shen Ting-Ting 
Published: June 2024

BACKGROUND
Chronic eczema significantly impacts daily life, social interactions, and quality of life; however, no curative treatment has been identified.
AIM
To determine the clinical efficacy of acupoint injection for chronic eczema and its influence on peripheral blood T cells.
METHODS
Eighty patients with chronic eczema treated at our hospital between June 2022 and March 2023 were randomly assigned to a control group (n = 40), which received conventional Western medicine treatment, or an observation group (n = 40), which received routine Western medicine treatment plus acupoint injection of triamcinolone acetonide. Response and adverse reaction rates, as well as differences in the levels of serum cytokines IFN-γ, IL-2, IL-4, and IL-10 before and after treatment were investigated.
RESULTS
No difference in overall response rates were found between the observation and control groups (100% vs 90%, respectively; P > 0.05); however, the observation group had a higher marked response rate than the control group (87.5% vs 52.5%; P < 0.05). Both groups had decreased Eczema Area and Severity Index scores and increased pruritus after treatment (P < 0.05), particularly in the observation group (P < 0.05). The observation group had an adverse reaction rate of 2.5% (1/40), which did not differ significantly from that of the control group (P > 0.05). The observation group exhibited higher post-treatment INF-γ and IL-2 but lower IL-4 levels than the control group (P < 0.05); however, no significant inter-group difference was observed in post-treatment IL-10 levels (P > 0.05).
CONCLUSION
Acupoint injection of triamcinolone acetonide is safe and effective in treating chronic eczema. Its therapeutic mechanism is related to the regulation of peripheral blood T cell levels, inhibition of inflammatory reactions, and mitigation of immune imbalance.
Effects of Tongluo Jiedu prescription on immune function and oxidative stress in patients with oral cancer
Authors: Yin Yue , Yao Yuan , Li Yi-Jie , Zhao Li-Li , Zhang Qiang 
Published: June 2024

BACKGROUND
Oral cancer, which is caused by mucous membrane variation, represents a prevalent malignant tumor in the oral and maxillofacial region, posing a significant threat to patients’ lives and safety. While surgical intervention stands as a cornerstone treatment for oral cancer patients, it carries the risk of incomplete treatment or high rates of postoperative recurrence. Hence, a multifaceted approach incorporating diverse treatment modalities is essential to enhance patient prognosis.
AIM
To analyze the application effect of Tongluo Jiedu prescription as adjuvant therapy and its influence on patient prognosis in patients with oral cancer.
METHODS
Eighty oral cancer patients in our hospital were selected and divided into the observation group and control group by a random number table. The control group was treated with continuous arterial infusion chemotherapy of cisplatin and 5-fluorouracil. The observation group was additionally given Tongluo Jiadu prescription. The inflammatory stress level, peripheral blood T-cell subsets, and immune function of the two groups were subsequently observed. SPSS 21.0 was used for data analysis.
RESULTS
The observation group demonstrated lower levels of interleukin-6 and C-reactive protein, and a higher level of tumor necrosis factor in comparison to the control group. After treatment, the immune function in the observation group was significantly better than in the control group.
CONCLUSION
Tongluo Jiedu prescription can improve the immune function and oxidative stress level of patients with oral cancer and accelerate the recovery process.
Rare etiology of colonic intussusception involving an adult with emphysematous cystic enteropathy: A case report and review of literature
Authors: Bergeron Eric , Pichette Maude , Boisvert Geneviève , Manière Thibaut , Désilets Étienne 
Published: June 2024

BACKGROUND
Pneumatosis cystoides intestinalis (PCI), characterized by a collection of gas-filled cysts in the intestinal wall, is an uncommon but well-known condition in gastroenterology. Abdominal pain is the most frequent symptom associated with PCI. Intussusception represents a potential cause of recurrent abdominal pain or emergency presentation. However, the occurrence of colonic intussusception secondary to PCI is very unusual in adulthood.
CASE SUMMARY
A 52-year-old male, known with idiopathic PCI, presented seventeen months after initial diagnosis with a new right upper quadrant pain. A computed tomography-scan demonstrated a colonic intussusception at the hepatic flexure. PCI did not progress compared with initial investigation. The patient underwent an emergency right hemicolectomy.
CONCLUSION
Resection was recommended in this case because PCI proved to be persisting with no identified curable cause. Surgery allowed to address the underlying pathology, the potential relapse of intussusception, and the likely cause of recurrent abdominal pain, either invagination or PCI itself.
Plasmacytosis mimicking multiple myeloma in angioimmunoblastic T-cell lymphoma: A case report and review of literature
Authors: Lin Chia-Ching , Lee Hsu-Lin , Chuo Hsin-Yi , Chen Tuo-An , Liu Ming-Yueh , Chen Li-Mien 
Published: June 2024

BACKGROUND
Angioimmunoblastic T-cell lymphoma (AITL) is a common subtype of peripheral T-cell lymphoma. Approximately half of patients with AITL may concurrently present with hypergammaglobulinemia. Increased numbers of plasma cells in the bone marrow are commonly observed at diagnosis. These tumors mimic plasma cell myelomas, hindering a conundrum of clinical diagnoses and potentially delaying appropriate treatment.
CASE SUMMARY
A 78-year-old woman experienced poor appetite, weight loss of 5 kg, fatigue 2 months before presentation, and shortness of breath 2 d before presentation, but no fever or night sweats. Physical examination revealed splenomegaly and many palpable masses over the bilateral axillary regions, approximately > 2 cm in size, with rubbery consistency and no tenderness. Blood tests revealed anemia and thrombocytopenia, lactate dehydrogenase level of 153 U/L, total protein level of 10.9 g/dL, albumin to globulin ratio of 0.2, and immunoglobulin G level more than the upper limit of 3000 mg/dL. The free kappa and lambda light chain concentrations were 451 and 614 mg/L, respectively. A pathological examination confirmed the diagnosis of AITL. The initial treatment was the cyclophosphamide, epirubicin, vincristine, and prednisolone regimen. Following this treatment, pleural effusion was controlled, and the patient was discharged in a stable condition and followed up in our outpatient department.
CONCLUSION
This report highlights the importance of differentiating reactive plasmacytosis from plasma cell myeloma in patients with hypergammaglobulinemia. A precise diagnosis of AITL requires a comprehensive evaluation, involving clinical, immunophenotypic, and histological findings conducted by a multidisciplinary team to ensure appropriate treatment.
Prostate cancer with elevated free prostate-specific antigen density: A case report
Authors: Huang Deng-Hui , Hu Yun-Xi , Guo Shuang , Yang Wen-Jiang 
Published: June 2024

BACKGROUND
Prostate cancer is the second most common cancer among men worldwide, and prostate-specific antigen (PSA) is often used in clinical practice to screen for prostate cancer. Normal total PSA (tPSA) level initially excludes prostate cancer. Here, we report a case of prostate cancer with elevated free PSA density (fPSAD).
CASE SUMMARY
A patient diagnosed with benign prostatic hyperplasia underwent prostatectomy, and the postoperative pathological results showed acinar adenocarcinoma of the prostate. The patient is currently undergoing endocrine chemotherapy.
CONCLUSION
We provide a clinical reference for diagnosis and treatment of patients with normal tPSA but elevated fPSAD.
THE SURVIVAL OF TOTAL ANKLE ARTHROPLASTIES: A DATA LINKAGE STUDY FROM THE NATIONAL JOINT REGISTRY
Authors: Jennison T. , Goldberg A. , Sharpe I. 
Published: June 2024

IntroductionDespite the increasing numbers of ankle replacements that are being performed there are still limited studies on the survival of ankle replacements and comparisons between different implants. The primary aim of this study is to link NJR data with NHS digital data to determine the true failure rates of ankle replacements. Secondary outcomes include analysis risk factors for failure, patient demographics and outcomes of individual prosthesis.MethodsA data linkage study combined National Joint Registry Data and NHS Digital data. The primary outcome of failure is defined as the removal or exchange of any components of the implanted device inserted during ankle replacement surgery. Life tables and Kaplan Meier survival charts demonstrated survivorship. Cox proportional hazards regression models with the Breslow method used for ties were fitted to compare failure rates.Results5,562 primary ankle replacement were recorded on the NJR. The 1-year survivorship was 98.8% (95% CI 98.4%–99.0%), 5-year survival in 2725 patients was 90.2% (95% CI 89.2%–91.1%), and 10-year survival in 199 patients was 86.2% (95% CI 84.6%–87.6%).When using a Cox regression model for all implants with over 100 implantations using the Infinity as the reference, only the Star (Hazard ratio 1.60 95% CI 0.87–2.96) and Inbone (HR 0.38 95% CI 0.05–2.84) did not produce significantly worse survivorship.ConclusionAnkle replacements have increased in numbers over the past decade, and the currently used implants have lower failure rates than older prosthesis. It is expected that in the future the outcomes of ankle replacements will continue to improve.
IS THE DIAGNOSIS OF FIFTH METATARSAL FRACTURE SUBTYPE CONSISTENT? AN INTEROBSERVER RELIABILITY STUDY
Authors: Chapman J. , Choudhary Z. , Gupta S. , Airey G. , Mason L. 
Published: June 2024

IntroductionTreatment pathways of 5th metatarsal fractures are commonly directed based on fracture classification, with Jones types for example, requiring closer observation and possibly more aggressive management.Primary objectiveTo investigate the reliability of assessment of subtypes of 5th metatarsal fractures by different observers.MethodsPatients were identified from our prospectively collected database. We included all patient referred to our virtual fracture clinic with a suspected or confirmed 5th metatarsal fracture. Plain AP radiographs were reviewed by two observers, who were initially trained on the 5th metatarsal classification identification. Zones were defined as Zone 1.1, 1.2, 1.3, 2, 3, diaphyseal shaft (DS), distal metaphysis (DM) and head. An inter-observer reliability analysis using Cohen's Kappa coefficient was carried out, and degree of observer agreement described using Landis & Koch's description. All data was analysed using IBM SPSS v.27.Results878 patients were identified. The two observers had moderate agreement when identifying fractures in all zones, apart from metatarsal head fractures, which scored substantial agreement (K=.614). Zones 1.1 (K=.582), 2 (K=.536), 3 (K=.601) and DS (K=.544) all tended towards but did not achieve substantial agreement. Whilst DS fractures achieved moderate agreement, there was an apparent difficulty with distal DS, resulting in a lot of cross over with DM (DS 210 vs 109; DM 76 vs 161). Slight agreement with the next highest adjacent zone was found when injuries were thought to be in zones 1.2, 1.3 and 2 (K=0.17, 0.115 and 0.152 respectively).ConclusionsReliability of sub-categorising 5th metatarsal fractures using standardised instructions conveys moderate to substantial agreement in most cases. If the region of the fracture is going to be used in an algorithm to guide a management plan and clinical follow up during a virtual clinic review, defining fractures of zones 1–3 needs careful consideration.
HOW DOES CARTIVA INTERPOSITIONAL ARTHROPLASTY COMPARE TO ARTHRODESIS IN THE TREATMENT OF HALLUX RIGIDUS? A RETROSPECTIVE COMPARATIVE STUDY WITH 12-MONTH FOLLOW-UP
Authors: Trowbridge S. , Lewis T. , Shehata R. , Lau B. , Lyle S. , Ray R. 
Published: June 2024

BackgroundHallux rigidus is a common condition characterised by first metatarsophalangeal joint (MTPJ) degeneration, pain and limited range of motion (ROM). The gold standard surgical treatment is arthrodesis, providing good pain relief but sacrifices ROM. Recently the Cartiva synthetic cartilage implant (SCI) has been utilised as an interpositional arthroplasty, aiming to reduce pain whilst preserving range of motion. Current evidence for Cartiva SCI is largely based on a single cohort with mixed outcomes. We sought to evaluate the clinical outcomes of Cartiva SCI compared to arthrodesis undertaken in our centre.MethodsRetrospective review of patients undergoing Cartiva SCI or arthrodesis for treating hallux rigidus was conducted. Preoperative arthritis was radiographically graded using the Vanore classification. Patient reported outcomes (PROMs) were assessed using EuroQol 5-dimension score (EQ-5D-5L) and Manchester-Oxford Foot Questionnaire (MOXFQ).ResultsBetween 2017 and 2020 there were 33 cases (17 Cartiva, 16 arthrodesis, mean age 59.0±9.9 years) with a mean follow up of 2.3 years. For the first MTPJ arthrodesis cohort, the MOXFQ domain scores were: Index 3.9±5.8, Walking/Standing 5.1±7.6, Pain 3.2±5.0, and Social Interaction 2.6±4.0. EQ-5D-5L Index score was 0.828±0.270 and the EQ-VAS was 72.5±23.3. For the Cartiva cohort, the MOXFQ domain scores were: Index 7.7±6.0, Walking/Standing 8.9±7.9, Pain 7.1±5.0, and Social Interaction 6.4±5.4. EQ-5D-5L Index score was 0.631±0.234 and the EQ-VAS was 74.8±20.8. There was no statistically significant difference between any MOXFQ domain or EQ-5D-5L scores. However, a negative trend in MOXFQ domains was identified for the Cartiva group, as well as a reoperation rate of 23.5%.ConclusionsThe Cartiva SCI demonstrated no advantage over arthrodesis in PROMs, despite the presumed benefit of preserved ROM. A significant reoperation rate was also observed. Surgeons should be cautious in the use of this novel implant.
Does a specialized assessment improve vocational outcomes for people on sick leave with a suspected common mental disorder? Results from the Mental Health Assessment Study (MeHAS)
Authors: Hoff Andreas , Bojesen Anders Bo , Fisker Jonas , Mandrup Poulsen Rie , Hjorthøj Carsten , Nordentoft Merete , Eplov Lene Falgaard 
Published: June 2024

Background
In Denmark, 50% of those on long-term sick leave are affected by common mental disorders (CMDs), and it has been argued that detection in primary care has been insufficient. The Mental Health Assessment Study (MeHAS) assesses if specialized mental health assessments can enhance return to work for this group. This study aimed to estimate the effect of a specialized mental health assessment for people on sick leave with a mental health disorder, on return to work and mental health care utilization.

Methods and findings
In this experimental study, sickness absentees were referred from a sick leave benefit management agency. Before intervention allocation, they had already received a standard health assessment in general practice. The intervention group received an additional specialized mental health assessment, while the control group did not. We compared the groups on several vocational outcome measures, the primary being proportion in work after one year. Other outcomes were weeks in work, time to return to work (RTW) and different measures of service utilization. We included 717 in the intervention group and 756 in the control group. On the primary outcome, proportion in work, we observed no differences between the groups at 12 months (53.9% vs. 58.7% in the control group, p = 0.133). Moreover, after one year, the control group showed faster RTW at 12-month follow-up (HR 0.79, p<0.001) and 3.1 more weeks in work (p<0.001). In the intervention group, participants received more hospital-based outpatient mental healthcare.

Conclusion
Providing a specialized mental health assessment was associated with fewer weeks in work and longer sick leave duration (secondary outcomes), but the proportion in work at 12-month follow-up (primary outcome) did not differ between the groups. The intervention was associated with a higher likelihood of receiving specialized mental healthcare services, perhaps because more needs were met. Given the substantial risk of selection bias, results should be treated with caution.