bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association of the perioperative fluid balance and cardiopulmonary complications in emergency gastrointestinal surgery: exploration of a randomized trial
Authors: Voldby Anders W. , Aaen Anne A. , Møller Ann M. , Brandstrup Birgitte 
Published: April 2024

Abstract
Background
The association between perioperative fluid administration and risk of complications following emergency surgery is poorly studied. We tested the association between the perioperative fluid balance and postoperative complications following emergency surgery for gastrointestinal obstruction or perforation.

Methods
We performed a re-assessment of data from the Goal-directed Fluid Therapy in Urgent Gastrointestinal Surgery Trial (GAS-ART) studying intra-operative stroke volume optimization and postoperative zero-balance fluid therapy versus standard fluid therapy. The cohort was divided into three groups at a perioperative fluid balance (FB) of low < 0 L, moderate 0–2 L, or high > 2 L. We used a propensity adjusted logistic regression to analyse the association with cardiopulmonary (primary outcome), renal, infectious, and wound healing complications. Further, the risk of complications was explored on a continuous scale of the FB.

Results
We included 303 patients: 44 patients belonged to the low-FB group, 108 to the moderate-FB group, and 151 to the high-FB group. The median [interquartile range] perioperative FB was –0.9 L [–1.4, –0.6], 0.9 L [0.5, 1.3], and 3.8 L [2.7, 5.3]. The risk of cardiopulmonary complications was significantly higher in the High-FB group 3.4 (1.5–7.6), p = 0.002 (odds ratio (95% confidence interval). On a continuous scale of the fluid balance, the risk of cardiopulmonary complications was minimal at –1 L to 1 L.

Conclusion
Following emergency surgery for gastrointestinal obstruction or perforation, a fluid balance < 2.0 L was associated with decreased risk of cardiopulmonary complications without increasing renal complications.
A systematic review on the relationship between socioeconomic conditions and emotional disorder symptoms during Covid-19: unearthing the potential role of economic concerns and financial strain
Authors: Chan Jee Kei , Marzuki Aleya A. , Vafa Samira , Thanaraju Arjun , Yap Jie , Chan Xiou Wen , Harris Hanis Atasha , Todi Khushi , Schaefer Alexandre 
Published: April 2024

Abstract
Background
Covid-19 has disrupted the lives of many and resulted in high prevalence rates of mental disorders. Despite a vast amount of research into the social determinants of mental health during Covid-19, little is known about whether the results are consistent with the social gradient in mental health. Here we report a systematic review of studies that investigated how socioeconomic condition (SEC)—a multifaceted construct that measures a person’s socioeconomic standing in society, using indicators such as education and income, predicts emotional health (depression and anxiety) risk during the pandemic. Furthermore, we examined which classes of SEC indicators would best predict symptoms of emotional disorders.

Methods
Following PRISMA guidelines, we conducted search over six databases, including Scopus, PubMed, etc., between November 4, 2021 and November 11, 2021 for studies that investigated how SEC indicators predict emotional health risks during Covid-19, after obtaining approval from PROSPERO (ID: CRD42021288508). Using Covidence as the platform, 362 articles (324 cross-sectional/repeated cross-sectional and 38 longitudinal) were included in this review according to the eligibility criteria. We categorized SEC indicators into ‘actual versus perceived’ and ‘static versus fluid’ classes to explore their differential effects on emotional health.

Results
Out of the 1479 SEC indicators used in these 362 studies, our results showed that 43.68% of the SEC indicators showed ‘expected’ results (i.e., higher SEC predicting better emotional health outcomes); 51.86% reported non-significant results and 4.46% reported the reverse. Economic concerns (67.16% expected results) and financial strains (64.16%) emerged as the best predictors while education (26.85%) and living conditions (30.14%) were the worst.

Conclusions
This review summarizes how different SEC indicators influenced emotional health risks across 98 countries, with a total of 5,677,007 participants, ranging from high to low-income countries. Our findings showed that not all SEC indicators were strongly predictive of emotional health risks. In fact, over half of the SEC indicators studied showed a null effect. We found that perceived and fluid SEC indicators, particularly economic concerns and financial strain could best predict depressive and anxiety symptoms. These findings have implications for policymakers to further understand how different SEC classes affect mental health during a pandemic in order to tackle associated social issues effectively.
Exploration of vocational high school students experiencing difficulty in cloze test performances: a mixed-methods study in Taiwan
Authors: Feng Kuo-Zheng 
Published: April 2024

AbstractThis study addressed a gap in existing research on Multiple-Choice (MC) cloze tests by focusing on the learners’ perspective, specifically examining the difficulties faced by vocational high school students (VHSs). A nationwide sample of 293 VHSs participated, providing both quantitative and qualitative data through a self-developed questionnaire. The results revealed that vocabulary and grammar posed the greatest challenges in the MC cloze test, while sentence patterns were perceived as the least difficult by VHSs. Factors contributing to these difficulties included the need for increased focus on vocabulary and grammar learning. Some participants attributed challenges to personal perceptions of intellectual capability, while others highlighted the influential role of teachers’ attitudes on their learning motivations and outcomes. The study suggested implications for test designs and teaching approaches. Despite these contributions, the study acknowledged limitations and offered suggestions for future research directions.
Trends in police complaints and arrests on New York City subways, 2018 to 2023: an interrupted time-series analysis
Authors: Roberts Leah E. , Mehranbod Christina A. , Bushover Brady , Gobaud Ariana N. , Eschliman Evan L. , Fish Carolyn , Zadey Siddhesh , Gao Xiang , Morrison Christopher N. 
Published: April 2024

Abstract
Background
Public transportation use is influenced by perceptions of safety. Concerns related to crime on New York City (NYC) transit have risen following NYC’s COVID-19 pandemic state of emergency declaration in 2020, leading to declines in subway ridership. In response, the most recent mayoral administration implemented a Subway Safety Plan in 2022. This study aimed to quantify the effects of the COVID-19 pandemic and the Subway Safety Plan on rates of complaints to and arrests by the New York City Police Department (NYPD) Transit Bureau.

Methods
Using publicly available data on complaints and arrests, we conducted interrupted time-series analyses using autoregressive integrated moving average models applied to monthly data for the period from September 2018 to August 2023. We estimated changes in the rates of complaints to and arrests by the NYPD Transit Bureau before and after: (1) the COVID-19 pandemic state of emergency declaration (i.e., March 2020), and (2) the announcement of the Subway Safety Plan (i.e., February 2022). We also examined trends by complaint and arrest type as well as changes in proportion of arrests by demographic and geographic groups.

Results
After the COVID-19 pandemic declaration, there was an 84% increase (i.e., an absolute increase of 6.07 per 1,000,000 riders, CI 1.42, 10.71) in complaints to the NYPD Transit Bureau, including a 99% increase (0.91 per 1,000,000 riders, CI 0.42, 1.41) in complaints for assault and a 125% increase in complaints for harassment (0.94 per 1,000,000 riders, CI 0.29, 1.60). Following the Subway Safety Plan there was an increase in the rate of arrests for harassment (0.004 per 1,000,000 riders, CI 0.001, 0.007), as well as decreases in the proportion of arrests for individuals racialized as White (− 0.02, CI − 0.04, − 0.01) and proportion of arrests in the borough of Manhattan (− 0.13, CI − 0.17, − 0.09).

Conclusions
The increased rates of complaints to the NYPD Transit Bureau following the onset of the COVID-19 pandemic remained elevated following the enactment of the Subway Safety Plan. Further evaluation efforts can help identify effective means of promoting safety on public transportation.
Comparison of smokers’ mortality with non-smokers following out-of-hospital cardiac arrests: a systematic review and meta-analysis
Authors: Zhang Nai , Liu Yu-Juan , Yang Chuang , Zeng Peng , Gong Tao , Tao Lu , Zheng Ying , Dong Shuang-Hu 
Published: April 2024

AbstractObjectiveAlthough some studies have linked smoking to mortality after out-of-hospital cardiac arrests (OHCAs), data regarding smoking and mortality after OHCAs have not yet been discussed in a meta-analysis. Thus, this study conducted this systematic review to clarify the association.MethodsThe study searched Medline-PubMed, Web of Science, Embase and Cochrane libraries between January 1972 and July 2022 for studies that evaluated the association between smoking and mortality after OHCAs. Studies that reportedly showed relative risk estimates with 95% confidence intervals (CIs) were included.ResultsIncorporating a collective of five studies comprising 2477 participants, the analysis revealed a lower mortality risk among smokers in the aftermath of OHCAs compared with non-smokers (odds ratio: 0.77; 95% CI 0.61–0.96;P < 0.05). Egger's test showed no publication bias in the relationship between smoking and mortality after OHCAs.ConclusionsAfter experiencing OHCAs, smokers had lower mortality than non-smokers. However, due to the lack of data, this ‘smoker’s paradox’ still needs other covariate effects and further studies to be considered valid.
Constructing predictive models for seismic oscillation parameters using covariance functions and Doppler effect phenomena: A case study of InSight mission V2 data
Authors: Skeivalas Jonas , Paršeliūnas Eimuntas , Šlikas Dominykas , Obuchovski Romuald , Putrimas Raimundas 
Published: April 2024

Abstract
An ability to construct predictive models for identifying seismic oscillation parameters by using the mathematics of covariance functions and Doppler effect phenomena is examined in this work. In the calculations, the Mars seismic oscillations measurement data from InSight Mission V2, observed in the months May, June and July of 2019, was used. To analyze the observation data arrays the Doppler phenomena and the expressions of covariance functions were employed. The seismic oscillations trend's intensity vectors were assessed by least squares method, and the random errors of measurements at the stations were eliminated partially as well. The estimates of the vector's auto-covariance and cross-covariance functions were derived by altering the quantization interval on the general time scale while varying the magnitude of the seismic oscillation vector on the same time scale. To detect the mean values of z —the main parameter of Doppler expression— we developed a formula by involving the derivatives of cross-covariance functions of a single vector and algebraic sum of the relevant vectors.
Maximisation of synchronisability under low injection power
Authors: Tanaka Hisa-Aki , Yabe Yoji , Suga Somei , Keida Akira , Maeda Kai , Mori Fumito , Sekiya Hiroo 
Published: April 2024

Abstract
Synchronisability of limit cycle oscillators has been measured by the width of the synchronous frequency band, known as the Arnold tongue, concerning external forcing. We clarify a fundamental limit on maximizing this synchronisability within a specified extra low power budget, which underlies an important and ubiquitous problem in nonlinear science related to an efficient synchronisation of weakly forced nonlinear oscillators. In this letter, injection-locked Class-E oscillators are considered as a practical case study, and we systematically analyse their power consumption; our observations demonstrate the independence of power consumption in the oscillator from power consumption in the injection circuit and verify the dependency of power consumption in the oscillator solely on its oscillation frequency. These systematic observations, followed by the mathematical optimisation establish the existence of a fundamental limit on synchronisability, validated through systematic circuit simulations. The results offer insights into the energetics of synchronisation for a specific class of injection-locked oscillators.
Degron tagging for rapid protein degradation in mice
Authors: Hernández-Morán Brianda A. , Taylor Gillian , Lorente-Macías Álvaro , Wood Andrew J. 
Published: April 2024

ABSTRACT
Degron tagging allows proteins of interest to be rapidly degraded, in a reversible and tuneable manner, in response to a chemical stimulus. This provides numerous opportunities for understanding disease mechanisms, modelling therapeutic interventions and constructing synthetic gene networks. In recent years, many laboratories have applied degron tagging successfully in cultured mammalian cells, spurred by rapid advances in the fields of genome editing and targeted protein degradation. In this At a Glance article, we focus on recent efforts to apply degron tagging in mouse models, discussing the distinct set of challenges and opportunities posed by the in vivo environment.
Aβ peptide enhances GluA1 internalization via lipid rafts in Alzheimer's-related hippocampal LTP dysfunction
Authors: Midorikawa Ryosuke , Wakazono Yoshihiko , Takamiya Kogo 
Published: April 2024

ABSTRACT
Amyloid β (Aβ) is a central contributor to neuronal damage and cognitive impairment in Alzheimer's disease (AD). Aβ disrupts AMPA receptor-mediated synaptic plasticity, a key factor in early AD progression. Numerous studies propose that Aβ oligomers hinder synaptic plasticity, particularly long-term potentiation (LTP), by disrupting GluA1 (encoded by GRIA1) function, although the precise mechanism remains unclear. In this study, we demonstrate that Aβ mediates the accumulation of GM1 ganglioside in lipid raft domains of cultured cells, and GluA1 exhibits preferential localization in lipid rafts via direct binding to GM1. Aβ enhances the raft localization of GluA1 by increasing GM1 in these areas. Additionally, chemical LTP stimulation induces lipid raft-dependent GluA1 internalization in Aβ-treated neurons, resulting in reduced cell surface and postsynaptic expression of GluA1. Consistent with this, disrupting lipid rafts and GluA1 localization in rafts rescues Aβ-mediated suppression of hippocampal LTP. These findings unveil a novel functional deficit in GluA1 trafficking induced by Aβ, providing new insights into the mechanism underlying AD-associated cognitive dysfunction.
Shared-Ride Efficiency of Ride-Hailing Platforms
Authors: Taylor Terry A. 
Published: April 2024

Problem definition: Ride-hailing platforms offering shared rides devote effort to reducing the trip-lengthening detours that accommodate fellow customers’ divergent transportation needs. By reducing shared-ride delay, improving shared-ride efficiency has the twin benefits of making shared rides more attractive to customers and increasing the number of customers a driver can serve per unit time. Methodology/results: We analytically model a ride-hailing platform that can offer individual rides and shared rides. We establish results that are counter to naive intuition: greater customer sensitivity to shared-ride delay and greater labor cost can reduce the value of improving shared-ride efficiency, and an increase in shared-ride efficiency can prompt a platform to add individual-ride service. We show that when network effects are small, increasing shared-ride efficiency pushes wages to extremes: if the current wage is high (low), increasing shared-ride efficiency pushes the wage higher (lower). We provide a sharp characterization of whether shared-ride efficiency and labor supply are complements or substitutes. We provide simple conditions under which increasing shared-ride efficiency reduces (alternatively, increases) labor welfare. We provide evidence that increasing shared-ride efficiency increases consumer surplus. Managerial implications: Our results inform a platform’s decision of whether to invest in improving shared-ride efficiency, as well as how to change its service offering and wage, as shared-ride efficiency improves. Supplemental Material: The online supplement is available at https://doi.org/10.1287/msom.2021.0545 .
A Comprehensive Systematic Review on the Multifaceted Factors Influencing Teacher Flourishing
Authors: Yulisinta Florence , Setiadi Bernadette Narulina , Suci Eunike Sri Tyas 
Published: April 2024

<p>Teacher flourishing encompasses a broad range of well-being, encompassing hedonic (pleasure-based) and eudaimonic (meaning-based) satisfactions. In the context of the literature review, a concise overview is provided, consisting of definitions, predictors, mediators, and outcomes. Conforming to the PRISMA protocol, the present review progresses through four stages: identification, screening, eligibility assessment, and including relevant studies. Furthermore, the search strategy focused on flourishing, well-being, and measuring tools, leveraging databases such as EBSCO Host, Proquest, Science Direct, and DOAJ. In line with the PRISMA statement, systematic review methodology guides the final analysis, incorporating twenty-seven studies published between 2017 and 2023. Despite being studied in numerous theoretical frameworks, teacher flourishing needs a more widely accepted definition and operational framework in studying the concept. The results show that multiple factors impact teacher flourishing, including individual, relational, and organizational elements. Additionally, the evaluation considers direct and indirect predictors, mediators, and outcomes. The new model is related to global well-being, including emotional, psychological, social, and spiritual aspects, stating the connections of these elements. The implications of the results can be effectively applied within educational settings by teachers, policymakers, and scholars specializing in education.</p>

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Equity, diversity and inclusion in neurosurgery: results of the SBNS engagement survey
Authors:   Equity, Diversity and Inclusion Working Group, Society of British Neurological Surgeons
Published: April 2024

INTRODUCTION Bullying, undermining and harassment (BUH) as well as discrimination have shown to be present throughout the National Health Service, especially in surgery. The Society of British Neurological Surgeons (SBNS) created its equity, diversity and inclusion (EDI) group to investigate the demographics of UK and Irish neurosurgeons, along with their experiences of BUH. METHODS A 31-item electronic survey was distributed through the national society email list for all neurosurgeons throughout the UK and Ireland in spring 2022. Descriptive statistics were used to present the results, along with 2x2 chi-squared contingency tables, with a p-value of <0.05 deemed statistically significant. RESULTS There were 175 respondents (approximately 18% of neurosurgeons in the UK and Ireland). Two-thirds (67%) were consultants and a quarter (23%) were women. Almost half (44%) were White British/Irish. A third (30%) went to university outside the UK/Ireland although most (82%) completed neurosurgical training in the UK or Ireland. Thirty-eight per cent said they did not have a primary caregiver or parental role. Two-thirds (65%) of respondents stated that they had been a victim of BUH, with 70% having witnessed BUH. Being female was the only demographic category with a significantly increased likelihood of experiencing BUH. A quarter (23%) of respondents felt uncomfortable about being open about themselves in the workplace and 39% had perceived a barrier to career progression due to a particular characteristic. CONCLUSIONS BUH and barriers to feeling comfortable in the workplace/career progression are problems in UK/Irish neurosurgery. Further work will be undertaken by the SBNS EDI working group to better understand the demographics of its community, to spread awareness of the issues, and to improve the experiences of neurosurgeons in the UK and Ireland.
Successful treatment of recurrent visceral leishmaniasis relapse in an immunocompetent adult female with functional hypopituitarism in Bangladesh
Authors: Hannan Tabiha Binte , Hossain Zazeba , Roy Utshab , Rahman S. M. Mahbubur , Rahman Md Sadiqur , Sabah Sadia , Rahat Md. Abu , Chowdhury Rajashree , Hossain Faria , Mondal Dinesh , Saha Shampa , Haq Tahniyah , Alam Md Rafiqul , Chowdhury Fazle Rabbi 
Published: April 2024

Background
Currently available treatment options are mostly effective in achieving long-term cure in visceral leishmaniasis (VL) patients. However, there have been reports of recurrence of this illness in both immunosuppressed and immunocompetent patients.

Case presentation
We report the first case of recurrent VL relapse in a 19-year-old immunocompetent female with functional hypopituitarism (hypogonadotropic hypogonadism with central hypothyroidism) from Bangladesh, who has been treated three times previously with optimal dosage and duration- liposomal amphotericin B (LAmB) alone and in combination with miltefosine. We treated the patient successfully with a modified treatment regimen of 10 mg/kg body weight LAmB for two consecutive days along with oral miltefosine for seven days as loading dose. For secondary prophylaxis, the patient received 3 mg/kg body weight LAmB along with oral miltefosine for seven days monthly for five doses followed by hormonal replacement. The patient remained relapse free after 12 months of her treatment completion.

Conclusion
In the absence of protective vaccines against Leishmania species and standard treatment regimen, this modified treatment regimen could help the management of recurrent relapse cases.