bluuebunny/crossref_metadata_2025_split huggingface dataset:
Innova4Health: an integrated approach for prevention of recurrence and personalized treatment of Major Depressive Disorder
Authors: Monaco Francesco , Vignapiano Annarita , Piacente Martina , Farina Federica , Pagano Claudio , Marenna Alessandra , Leo Stefano , Vecchi Corrado , Mancuso Carlo , Prisco Vincenzo , Iodice Davide , Auricchio Annarosaria , Cavaliere Roberto , D'Agosto Amelia , Fornaro Michele , Solmi Marco , Corrivetti Giulio , Fasano Alessio 
Published: May 2024

BackgroundMajor Depressive Disorder (MDD) is a prevalent mental health condition characterized by persistent low mood, cognitive and physical symptoms, anhedonia (loss of interest in activities), and suicidal ideation. The World Health Organization (WHO) predicts depression will become the leading cause of disability by 2030. While biological markers remain essential for understanding MDD's pathophysiology, recent advancements in social signal processing and environmental monitoring hold promise. Wearable technologies, including smartwatches and air purifiers with environmental sensors, can generate valuable digital biomarkers for depression assessment in real-world settings. Integrating these with existing physical, psychopathological, and other indices (autoimmune, inflammatory, neuroradiological) has the potential to improve MDD recurrence prevention strategies.MethodsThis prospective, randomized, interventional, and non-pharmacological integrated study aims to evaluate digital and environmental biomarkers in adolescents and young adults diagnosed with MDD who are currently taking medication. The study implements a sensor-integrated platform built around an open-source “Pothos” air purifier system. This platform is designed for scalability and integration with third-party devices. It accomplishes this through software interfaces, a dedicated app, sensor signal pre-processing, and an embedded deep learning AI system. The study will enroll two experimental groups (10 adolescents and 30 young adults each). Within each group, participants will be randomly allocated to Group A or Group B. Only Group B will receive the technological equipment (Pothos system and smartwatch) for collecting digital biomarkers. Blood and saliva samples will be collected at baseline (T0) and endpoint (T1) to assess inflammatory markers and cortisol levels.ResultsFollowing initial age-based stratification, the sample will undergo detailed classification at the 6-month follow-up based on remission status. Digital and environmental biomarker data will be analyzed to explore intricate relationships between these markers, depression symptoms, disease progression, and early signs of illness.ConclusionThis study seeks to validate an AI tool for enhancing early MDD clinical management, implement an AI solution for continuous data processing, and establish an AI infrastructure for managing healthcare Big Data. Integrating innovative psychophysical assessment tools into clinical practice holds significant promise for improving diagnostic accuracy and developing more specific digital devices for comprehensive mental health evaluation.
Immediate loading in partially edentulous patients with fixed implant-supported restorations cases report
Authors: Wang Shuang , Duan Siyi , Chen Rui , Wang Zijian , Tang Yulong 
Published: May 2024

ObjectivesThis article reports on four rare cases involving multiple trauma-induced adjacent missing anterior teeth in the maxillary or mandibular region. These cases were successfully treated using a 4-axial implant-based alternative insert and an immediate loading protocol.Material and methodsThis series of cases was summarized by retrospective study that 4 patients who received a total of 20 immediately loaded implants. These patients had suffered from trauma-induced loss of 8–9 adjacent anterior teeth. The 4-axial-implants were inserted with the assistance of digital pioneer drill guides. The surgical procedure involved alveolar bone trimming or ultrasonic osteotomy, eliminating the need for traditional large-area bone augmentation. Pre- and post-operative CBCT was matched using DTX Studio Implant software, the deviation of implant between actual position and preoperative design was measured and compared using SPSS software package.ResultsThe average follow-up duration 48 months after implant prostheses, the cumulative retention rate of the implants was 100%, the marginal bone loss averaged 0.53 mm (SD 0.15 mm), and buccal plate bone loss averaged 0.62 mm (SD 0.41 mm).ConclusionsThis retrospective clinical report demonstrates the successful treatment of several patients with multiple adjacent maxillary or mandibular anterior teeth using four implant-supported screws to fix the frame and employing immediate loading. The approach resulted in long-term stable clinical outcomes. Moreover, the method not only shortens the period of edentulism but also facilitates easy disassembly, maintenance, and cleaning. Consequently, it emerges as a highly favorable clinical option for patients suffering from extensive tooth loss.
Prevalence and appropriateness of omeprazole prescription in dogs at a veterinary teaching hospital before and after the publication of the ACVIM consensus statement on the rational administration of gastrointestinal protectants
Authors: Sainz Ángel , García-Sancho Mercedes , Villaescusa Alejandra , Rodríguez-Franco Fernando , Díaz-Regañón David , Olmeda Patricia , Marks Stanley L. 
Published: May 2024

IntroductionOverprescribing of acid suppressants is a common phenomenon in human and small animal patients, leading to potential deleterious gastrointestinal (GI) and non-GI consequences. The impact of consensus statements on veterinary prescribing habits in clinical practice have not been fully evaluated. This study aimed to compare the prescribing habits of the proton pump inhibitor (PPI), omeprazole, in dogs in an academic veterinary teaching hospital before and after the publication of the American College of Veterinary Internal Medicine (ACVIM) consensus statement on rational use of gastrointestinal protectants.MethodsEvaluation of the prescribing habits of omeprazole in dogs during the years 2017 and 2021 was retrospectively compared. These years were selected to reflect a 12-month period prior to and following the publication of the consensus statement. One hundred dogs from each year were randomly selected. Dose, frequency of administration, duration of treatment, concurrent prescription of more than one gastroprotectant and indications for prescribing omeprazole were analyzed.ResultsA significant increase in the cases that received omeprazole q12h (p &lt; 0.0001) or that underwent a tapering dose after ≥4 week-therapy (p &gt; 0.0001) was detected after the publication of the 2018 ACVIM consensus statement. Considering the indications, there was also a significant increase in the appropriate prescription of omeprazole in the second compared to the first period of study (p &lt; 0.0001). Fifteen of 16 clinicians (94%) involved in the prescription of omeprazole indicated that their reading of the consensus statement had changed their clinical practice regarding PPI administration in dogs.DiscussionThese results support the beneficial impact of the ACVIM consensus statement on the judicious prescribing of omeprazole in an academic veterinary hospital. These results should not be extrapolated to first-opinion veterinary practices, and further efforts should be made to ensure that PPIs are prescribed prudently with a clear indication and regular review of the appropriateness of continued administration to minimize possible risks and adverse drug interactions.
Women Are Also Disadvantaged in Accessing Transplant Outside the United States: Analysis of the Spanish Liver Transplantation Registry
Authors: Tejedor Marta , Neria Fernando , De La Rosa Gloria , Almohalla Álvarez Carolina , Padilla María , Boscà Robledo Andrea , Fundora Suárez Yiliam , Sánchez-Bueno Francisco , Gómez-Bravo Miguel Angel , Berenguer Marina 
Published: May 2024

Sex inequities in liver transplantation (LT) have been documented in several, mostly US-based, studies. Our aim was to describe sex-related differences in access to LT in a system with short waiting times. All adult patients registered in the RETH-Spanish Liver Transplant Registry (2000–2022) for LT were included. Baseline demographics, presence of hepatocellular carcinoma, cause and severity of liver disease, time on the waiting list (WL), access to transplantation, and reasons for removal from the WL were assessed. 14,385 patients were analysed (77% men, 56.2 ± 8.7 years). Model for end-stage liver disease (MELD) score was reported for 5,475 patients (mean value: 16.6 ± 5.7). Women were less likely to receive a transplant than men (OR 0.78, 95% CI 0.63, 0.97) with a trend to a higher risk of exclusion for deterioration (HR 1.17, 95% CI 0.99, 1.38), despite similar disease severity. Women waited longer on the WL (198.6 ± 338.9 vs. 173.3 ± 285.5 days, p &lt; 0.001). Recently, women’s risk of dropout has reduced, concomitantly with shorter WL times. Even in countries with short waiting times, women are disadvantaged in LT. Policies directed at optimizing the whole LT network should be encouraged to guarantee a fair and equal access of all patients to this life saving resource.
PERTOLONGAN PERTAMA PENANGANAN TERSEDAK PADA ANAK PRA SEKOLAH
Authors: Awaluddin Awaluddin , Syarifah Anita , Irwan M. Irwan , Riamah Riamah 
Published: May 2024

Penyempitan jalan napas bisa berakibat fatal jika itu mengarah pada gangguan serius oksigenasi dan ventilasi. Kondisi tersedak pada anak dapat menimbulkan situasi kegawatdaruratan respirasi yang jika tidak ditangani dengan segera dapat mengancam jiwa ataupun kecacatan anak. Penanganan yang dilakukan biasanya berhasil dan tingkat kelangsungan hidup sebesar 95%. Tujuan pengabdian masyarakat ini untuk mengetahui dan mengaplikasikan prosedur pertolongan pertama pada anak tersedak (choking). Metode pengabdian masyarakat ini dilakukan dengan ceramah, demonstrasi dengan alat peraga dan tanya jawab. Kesimpulan didapatkan orangtua dan guru mampu mengetahui dan mengaplikasikan pertolongan pertama pada anak tersedak (choking) sesudah diberikan pelatihan.
SOCIALIZATION OF THE PREVENTION OF SEXUAL HARASSMENT AS A FORM OF CHARACTER EDUCATION IN THE DIGITAL ERA IN HIGH SCHOOLS (SMA NEGERI 1 STM HILIR)
Authors: Barus Depitaria Br , Keliat Venia Utami 
Published: May 2024

Fungsi pendidikan seksual sejak dini memberikan pemahaman tentang seksualitas yang berguna dan bermanfaat bagi anak -anak generasi penerus bangsa, sebagai upaya meminimalisir dan mencegah perbuatan menyimpang. Sosialisasi akan bahasa pelecehan seksual sangat penting karena bisa terjadi dimana saja, salah satunya di lingkungan sekolah. Beberapa temuan masalah yang kami survey pada SMA Negeri 1 STM Hilir yaitu 1) Minimnya pengetahuan terkait pendidikan seks serta bahaya pelecehan seksual. 2) Minimnya pengetahuan mengenai Undang-Undang Perlindungan Hukum pada korban pelecehan seksual, 3) Kurangnya pembekalan etika dan moral terhadap siswa sebagai bentuk pendidikan karakter. Metode kegiatan ini yaitu ceramah dan pembekalan. Hasil dari kegiatan ini yaitu berupa kebijakan-kebijakan yang diterapkan oleh sekolah sebagai upaya pencegahan kasus pelecehan seksual.
Kata Kunci: Pelecehan Seksual,Pendidikan Karakter,Digitalisasi
PROACTIVE COPING DITINJAU DARI SELF EFFICACY PADA MAHASISWA YANG SEDANG MENYUSUN SKRIPSI DI PROGRAM STUDI SISTEM INFORMASI FAKULTAS TEKNOLOGI DAN ILMU KOMPUTER UNIVERSITAS PRIMA INDONESIA MEDAN
Authors: Sri Hartini Sri Hartini 
Published: May 2024

ABSTRACT

This study aims to find out relationship between self efficacy and proactive coping on students are writing essay in study program information systems faculty of technology computer science in University of Prima Indonesia Medan. The hypothesis of this study states that there is a positive correlation between self efficacy and proactive coping, assuming that the higher self efficacy, the higher will proactive coping be and conversely the lower the self efficacy the lower will proactive coping be. The subjects of this study were 101 students at Faculty of Technology and Computer Science University of Prima Indonesia selected by purposive sampling method. Data were obtained from a scale to measure self efficacy and proactive coping. The calculation was performed by means of testing requirements analysis (assumption), which consists of normality test for distribution and linearity test for relationships. The data analysis used is Product Moment Correlation with SPSS 17 for Windows. The results of data analysis showed that the correlation coefficient was 0.506 with p 0.000 (p <0.05). It shows that there is a positive relationship between self efficacy and proactive coping. These results indicate that the contribution of a given variable of self efficacy to proactive coping is at 26 percent, while the remaining 74 percent is influenced by other factors not examined. From these results, it is concluded that the hypothesis stating that there is a positive correlation between self efficacy and proactive coping is acceptable.

Keywords: Self Efficacy, Proactive Coping
Valoración de las competencias de empleabilidad en estudiantes peruanos de educación superior tecnológica: Un estudio comparativo
Authors: Saldarriaga Reto Doris Modesta , Huayta Franco Yolanda Josefina , Rodriguez Galán Darien Barramedo , Narvaez Aranibar Teresa 
Published: May 2024

Employability skills are essential to enter, maintain promotion and progress in employment, and are especially relevant in the labor market insertion of disadvantaged young people, hence the importance of the study to know the perception of students in the last cycles of studies in the understanding that their graduation is approaching. The objective of this study is to compare the assessment of employability from the perspective of Peruvian students, the context and their circumstances; the sample consisted of two groups of technological higher education students from the Peruvian coast and highlands; the dimensions assessed refer to the strengths and resources, weaknesses and deficiencies, impulse control, proactive behavior, and self-care and personal image they show towards the world of work. For the study, the online application of the EAS35 questionnaire called Employability appraisal scale was carried out, in which 593 students of the last cycles of studies participated, all participants were of legal age; it is a quantitative approach research, non-experimental design and comparative level. The findings reveal that the answers were mostly given by women with 67% of participation in the study, in addition to which it is evident that the percentage results have minimal variations between the students of both regions. It is concluded that there is a comprehensive approach to employability competency from two different contexts, which maintain the same strengths as weaknesses, there are high percentages of students who have not had any work experience despite being in the V and VI cycle, which are the last semesters of professional training.
Validación del inventario de actos de ciberacoso laboral (ICA-W)
Authors: Castillo Riquelme Víctor , Valdebenito Troncoso Josías , Torres Uribe Ignacio , Muñoz Otárola María Belén , Chávez Gómez Paulina 
Published: May 2024

Workplace cyberbullying is an emerging phenomenon that has received little attention in the academic literature. This research sought to validate an instrument to measure cyberbullying in work contexts. The ICA-W scale of Vranjes et al. (2018) was translated, and an exploration of its psychometric properties was conducted. Validity was assessed by exploratory factor analysis and through nomological network analysis with the constructs of psychological harassment, life satisfaction, and subjective happiness. The results support the quality of the instrument, finding a reliability of .88 and convergent validity with the psychological harassment scale (rho = .52), as well as divergent validity with the satisfaction with life scale (rho = -.17). Factor analysis revealed a unidimensional solution that explained 65% of the variance. It is concluded that the ICA-W scale is reliable and valid, but assuming certain restrictions in its application in Chilean workers.
Pengaruh Produk dan Harga terhadap Keputusan Konsumen Depot Air Minum (The Effect of Product and Price on Drinking Water Depot Consumer Decisions)
Authors: Purwanto Toni , Sumiyati Sumiyati 
Published: May 2024

Penelitian ini bertujuan untuk mengkaji pengaruh produk dan harga terhadap keputusan konsumen depot air minum yang dilakukan pada konsumen Azwa Qua di Rasau Jaya 1-Kubu Raya. Data dianalisis dari 100 responden dengan menggunakan purposive sampling. Beberapa analisis yang dilakukan dalam kajian ini yaitu, analisis regresi linier berganda, analisis koefisien korelasi (R), analisis koefisien determinasi (R2), uji pengaruh simultan (uji F) dan parsial (uji t). Hasil yang diperoleh dari penelitian ini menunjukkan variabel produk dan harga secara simultan berpengaruh terhadap keputusan konsumen, namun variabel harga tidak berpengaruh secara parsial terhadap keputusan konsumen. Hal ini disebabkan oleh harga yang ditetapkan pada depot air minum Azwa Qua tidak menjadi pertimbangan utama bagi konsumen dalam pengambilan keputusan.
Synthesis of core–shell nanoparticles with liquid core using magnetron sputtering and capacitively coupled dusty plasmas
Authors: Murugesh Munaswamy , Sasaki Koichi 
Published: May 2024

Abstract
We succeeded in depositing amorphous carbon films around tin nanodroplets retained in a capacitively coupled plasma (CCP). High-pressure magnetron sputtering was used for synthesizing tin nanoparticles at the top of a vacuum chamber. Tin nanoparticles were transported to CCP at the bottom of the chamber, and they were trapped in the sheath above an rf electrode. Tin nanoparticles were heated above the mp by ion bombardment in CCP. We introduced methane into CCP to deposit amorphous carbon films around melted tin nanoparticles. The transmission electron microscope (TEM) images of core–shell nanoparticles showed completely spherical cores. We observed the melting of cores at the melting point of metal tin when we heated core–shell nanoparticles in TEM, suggesting that the amorphous carbon films protected cores from the oxidation. In addition, the amorphous carbon films were robust against the volume expansion of the cores due to melting.
Science, Research, Education and Culture According to Eu Reports on Albania’s Progress
Authors: Reçi Mirjam 
Published: May 2024

This abstract explores a comparative analysis of the European Union's assessments of Albania's progress, focusing specifically on chapters 25 and 26 of these reports. Chapter 25 of the EU progress report examines matters concerning science and research, assessing Albania's achievements, challenges, and recommendations for improvement in these areas. Conversely, chapter 26 of the report focuses on education and culture, evaluating Albania's advancements, identifying obstacles, and suggesting strategies for further development. By examining the key areas of progress, challenges encountered, and recommendations provided by the EU in these sectors, this analysis illuminates Albania's path toward EU integration, offering valuable insights into areas that require additional attention and enhancement. This comparative analysis provides a thorough examination of Albania's progress in science, research, education, and culture, juxtaposed with the EU's evaluations and recommendations. By comparing these assessments, it illuminates both Albania's achievements and the enduring challenges in these vital sectors. Furthermore, it underscores the importance of these areas in Albania's EU integration journey, emphasizing the necessity for ongoing efforts and focused strategies to tackle the identified challenges and propel Albania closer to integration with the European Union.

Received: 28 February 2024 / Accepted: 26 April 2024 / Published: 5 May 2024
Revolutionizing Moroccan Education with AI: A Path to Customized Learning
Authors: - Rachid Ejjami 
Published: May 2024

This integrative literature review analyzes how AI, specifically Machine Learning (ML) and Large Language Models (LLMs), is used in Moroccan education. The study emphasizes the significance of modernizing traditional educational techniques. It investigates how artificial intelligence may personalize learning experiences, minimize educational disparities, and foster a culturally diverse and
technologically sophisticated learning environment. The ILR uses a conceptual framework that highlights customized learning, equitable education, technological innovation, and a systematic methodology that incorporates extensive literature synthesis. The research process thoroughly examines
multiple academic sources, including peer-reviewed articles, books, conference papers, and reports. The ILR identifies relevant patterns, barriers, and opportunities associated with integrating AI in Moroccan education by carefully studying and synthesizing data. The findings demonstrate the enormous potential of ML and LLMs in revolutionizing teaching methods, encouraging active student participation, and closing educational inequalities across Morocco. The paper finishes by underlining the need to incorporate AI into educational practice and identifying areas for future research. It emphasizes
investigating how AI may help Morocco and other countries modernize their education systems.
Phytochemical Investigation of Alysicarpus vaginalis by Gas Chromatography-mass Spectrometry and High-performance Thin-layer Chromatography
Authors: Savalia Vaibhavi , Padariya Jahnavi , Koshiya Tushar , Pandya Devang 
Published: May 2024

Introduction: Alysicarpus vaginalis belongs to the Fabaceae family, commonly known as buffalo clover and one-leaf clover. Alysicarpus vaginalis is medicinally used in disease-related kidney, diuretics, leprosy, pulmonary problems, jaundice, skin problems, respiratory difficulties, and as a hepatoprotective. Alysicarpus vaginalis is a medicinally important plant according to our review of literature on pharmacological activities, modern pharmacological activities, ethnomedicinal surveys, and traditional systems. However, very limited research related to phytochemical investigation by chromatographic techniques was studied.
Methods: So, to investigate the phytochemicals of Alysicarpus vaginalis methanol extract by High-performance thin-layer chromatography and gas chromatography-mass spectrometry.
Result: Phytochemical screening revealed the presence of steroids, flavonoids, polyphenols, terpenoids, carbohydrates, alkaloids, and tannins. GC-MS revealed, the presence of six out of nine phytochemicals found medicinally important. 4-O-Methylmannose, Undecane, Neophytadiene, 2-amino-5-[(2-carboxy) vinyl]- Imidazole, Lup-20(29)-en-3-one and stigmasterol are some of the important phytochemical useful as anticancer or as anti-inflammatory. A solvent system was developed by thin-layer chromatography, followed by the HPTLC analysis using the mobile phase toluene: methanol: ethyl acetate (7:3:1). High-performance thin-layer chromatography fingerprinting detected total of 8 peaks with Rf value of 0.007, 0.089, 0.142, 0.211, 0.468, 0.585, 0.772, and 0885 at 254nm and total of 9 peaks with Rf value of 0.007, 0.089, 0.140, 0.208, 0.468, 0.661, 0.772, 0887, and 0.940 at 366nm, respectively.
Conclusion: Chemoprofiling by sophisticated spectral techniques such as GC-MS and HPTLC fingerprinting can serve as an important tool for quality control of assuring purity, safety, quality, and efficacy of herbal formulation, and herbal extracts from Alysicarpus vaginalis.