bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unexpected Behavior of a Maltose-Negative Saccharomyces cerevisiae Yeast: Higher Release of Polyfunctional Thiols from Glutathionylated Than from Cysteinylated S-Conjugates
Authors: Simon Margaux , Christiaens Romain , Janssens Philippe , Collin Sonia 
Published: May 2024

At present, non-alcoholic and low-alcoholic beers (NABLABs), in addition to their premature sensitivity to oxidation, still suffer from a lack of fruity fermentation aromas. Maltose/maltotriose-negative yeasts offer a highly attractive alternative for creating diversified pleasant aromas and/or eliminating off-flavors in NABLAB production. The aim of this study was to explore the potential of Saccharomyces cerevisiae var. chevalieri, SafBrewTM LA-01 to release fruity polyfunctional thiols from glutathionylated (G-) and cysteinylated (Cys-) precursors. Interestingly, it proved to release free thiols from their glutathionylated S-conjugate much more efficiently (0.34% from G-3-sulfanylhexanol in 15 °P wort after seven days at 24 °C) than the best S. pastorianus strains previously screened (0.13% for lager yeast L7). On the other hand, despite its classification as a S. cerevisiae strain, it showed an inefficient use of cysteinylated precursors, although the release efficiency was slightly higher under NABLAB fermentation conditions (6 °P; 3 days at 20 °C). Under these conditions, as expected, LA-01 consumed only glucose, fructose, and saccharose (0.4% v/v ethanol formation) and produced only low levels of fermentation esters (1.6 mg/L in total) and dimethylsulfide (5 µg/L). The POF+ character of LA-01 also brought significant levels of 4-vinylguaiacol (810 μg/L), which could give to NABLABs the flavors of a white beer.
Serological and Molecular Survey of Babesia ovis in Healthy Sheep in Türkiye
Authors: Bozan Mehmet , Ulucesme Mehmet Can , Eyvaz Arda , Ceylan Onur , Sevinc Ferda , Aktas Munir , Ozubek Sezayi 
Published: May 2024

Babesiosis, caused by Babesia ovis, is a major seasonal issue in sheep, particularly in countries like Türkiye with high Rhipicephalus bursa tick populations. Previous studies employing various methods such as microscopy, serology, or molecular techniques have reported different epidemiological data concerning ovine babesiosis. Addressing this knowledge gap, our study employed a combined nested PCR (nPCR)/indirect ELISA (iELISA) approach, analyzing blood samples collected from 414 sheep between April and July 2023 using both techniques. nPCR amplified the 18S ribosomal RNA gene of B. ovis and determined a molecular prevalence of 1.9%. Conversely, serological testing using iELISA targeted the BoSA1 antigen and revealed a significantly higher positivity rate of 59.9% for anti-B. ovis antibodies. The temporary presence of Babesia after recovery reduces nPCR sensitivity, resulting in lower molecular prevalence. However, even if Babesia is not present in the host, anti-B. ovis antibodies remain in the serum for a long time and can be detected serologically. Our study underscores the necessity of concurrently employing molecular and serological methods for an accurate assessment of B. ovis prevalence. It highlights the importance of comprehensive epidemiological approaches for effective disease management in sheep populations.
Aplikasi Sistem Informasi Taman Pendidikan Al-Qur’an (TPA) Az-Zikra Berbasis Website Menggunakan Metode Rapid Application Development
Authors: Salsabila Nurul Nikma , Kekenusa John Socrates , Ngangi Stephano Caesar Wenston 
Published: May 2024

Pada era modern seperti sekarang, pemanfaatan teknologi informasi telah menjadi bagian penting dalam aktivitas sehari-hari. Sistem informasi merupakan sistem yang mengolah data menjadi sebuah informasi dan website sebagai media sarana penyampaian informasi yang menjadi sangat penting. Taman Pendidikan Al-Qur’an (TPA) Az-zikra merupakan lembaga pendidikan non-formal jenis keagamaan komunitas muslim yang menjadikan al-Qur’an sebagai materi utamanya, dan untuk menjadikan generasi muda yang qur’ani dan membumikan Al-Qur’an. Berlokasi di Kecamatan Patampanua, Kabupaten Pinrang, Sulawesi Selatan, dan didirikan pada tahun 2016. Tempat ini memfokuskan bagi anak-anak yang beragama islam dengan rentang usia 7-12 tahun. Namun, dalam pengelolaan data, TPA Az-zikra menggunakan metode konvensional. Pencatatan pendaftar, santri, pengajar, dan data internal TPA dilakukan secara manual, menyebabkan data tersebar dan sulit dikelola. Selain itu, minimnya usaha dalam menyebarkan informasi mengenai TPA Az-zikra juga mengakibatkan rendahnya pengetahuan masyarakat tentang lembaga ini. Untuk mengatasi masalah ini, peneliti bertujuan untuk membuat suatu aplikasi sistem informasi berbasis website dengan menggunakan metode rapid application development (RAD). Penelitian ini menghasilkan sebuah aplikasi sistem informasi berbasis website yang dapat digunakan untuk memudahkan pengguna mendaftar menjadi santri pada Taman Pendidikan Al-Qur’an (TPA) Az-zikra secara online, dan pada pihak Taman Pendidikan Al-Qur’an (TPA) Az-zikra akan lebih mudah dalam mengelola data santri, data pengajar dan informasi-informasi penting tentang Taman Pendidikan Al-Qur’an (TPA) Az-zikra agar dapat diketahui oleh masyarakat luar.
IMPACTO DO USO DE PRÓTESE TOTAL NA QUALIDADE DE VIDA DE PACIENTES IDOSOS: REVISÃO DE LITERATURA
Authors: Inácio Araújo Geovanna , Matias de França Gescica Natália , Da Silva Sousa Mota Ana Beatriz , Vieira Andrade Jahnsley Lorran Santiago , Inácio Azevedo Karynne , De Souza Viana Larissa , Rodrigues Dias Marcus Vinicius , Melo Mendes dos Santos Roberta , Furtado Carvalho Roberta 
Published: May 2024

INTRODUÇÃO: O edentulismo pode causar diversos problemas físicos e psicológicos, afetando desde a mastigação, até a capacidade de sorrir. No entanto, com o uso da prótese total, esses problemas podem ser minimizados, tendo assim um impacto significativo na qualidade de vida e autoestima dos idosos. OBJETIVOS: Este trabalho tem como objeto de estudo a qualidade de vida dos pacientes idosos que optam pelo uso da prótese total. METODOLOGIA: Trata-se de uma revisão de literatura integrativa, onde foram utilizados 06 artigos encontrados através da base de dados PubMed e LILACS. Os critérios de inclusão foram artigos da língua português e inglesa, publicados entre os anos de 2018 a 2021. Os critérios de exclusão foram teses, dissertações, artigos pagos e trabalhos de conclusão de curso. RESULTADOS: A perca dentária ainda é uma realidade infeliz para muitos pacientes, especialmente para os idosos. As alterações advindas do edentulismo incluem aos níveis funcional, neuromuscular e fisiológico. Como opção de tratamento para o edentulismo, a prótese total convencional representa uma alternativa viável e segura para a maioria dos pacientes idosos. CONCLUSÃO: O edentulismo em idosos ainda constitui um desafio para os profissionais da odontologia, onde a prótese total tem um impacto significativo na qualidade de vida dos idosos, prevenindo pressão aos tecidos bucais, proporcionando conforto e alívio de dor, devolvendo a capacidade de sorrir sem constrangimento, melhorando sua autoimagem e interação social.
A INCIDÊNCIA DA STAPHYLOCOCCUS AUREUS EM HOSPITAIS: REVISÃO DE OBRA
Authors: Nascimento Evelyn Caroline Pantoja do , Santos Pollianna Cristina dos , Castro Samuel Henrique Malcher de 
Published: May 2024

O gênero Staphylococcus aureus (S. aureus) é um dos microrganismos mais comuns no ambiente hospitalar, sendo responsáveis por muitas das infecções adquiridas no hospital. Este patógeno possui vários mecanismos de virulência, incluindo a formação de biofilme e a multirresistênciaà antibióticos. Trata-se de uma revisão integrativa de literatura. A busca dos estudos ocorreu entre abril e maio de 2024 nas bases de dados Biblioteca Virtual em Saúde (BVS), PubMed e SciELO. Como descritores foram selecionadas expressões constituintes dos Descritores em Ciências da Saúde (DeCS) da BVS e da Medical Subject Headings (MeSH): “Infecção hospitalar”, “Staphylococcus aureus” e “Resistência a Medicamentos”. A resistência do Staphylococcus aureus a antibióticos é um grande desafio clínico, principalmente devido à rápida disseminação de cepas resistentes. A detecção da Staphylococcus aureus em hospitais pode ser realizada por diferentes métodos, incluindo culturas microbiológicas, testes de suscetibilidade a antibióticos e técnicas moleculares avançadas como a PCR em tempo real. O tratamento de infecções por Staphylococcus aureus geralmente envolve antibioticoterapia e terapia combinada, dependendo da gravidade da infecção. A incidência da Staphylococcus aureus em hospitais é um problema significativo que requer atenção e medidas de controle eficazes. A resistência a antibióticos por parte da bactéria torna o tratamento das infecções mais desafiador, destacando a importância da prevenção.
DESIGN OF A MEDICAL INFORMATION SUBSYSTEM FOR DISPENSARY OBSERVATION
Authors: Новиков М.К. , Коровин Е.Н. , Новикова Е.И. , Сергеева М.А. 
Published: May 2024

В настоящее время в РФ проводится всеобщая диспансеризация взрослого населения. Диспансеризация и диспансерное наблюдение необходимы для профилактики, раннего выявления и в дальнейшем квалифицированного лечения хронических неинфекционных заболеваний. Все хронические заболевания развиваются постепенно и не на пустом месте. Условия, при которых вероятность возникновения заболевания становится выше, называются факторами риска. Факторы риска можно выявить задолго до того, как возникнут первые симптомы заболевания, а их коррекция позволяет значительно снизить и даже полностью предупредить развитие заболевания. К тому же выявить эти факторы значительно проще и дешевле, чем потом диагностировать и лечить уже развившийся недуг. Кроме того, выявление заболевания на ранних стадиях его развития позволяет значительно быстрее и эффективнее провести лечение и даже достигнуть полного выздоровления. Для разработки подсистемы для диспансерного наблюдения была построена контекстная диаграмма деятельности и диаграммы декомпозиции, диаграммы классов, и разработана структурированная база данных. С помощью данной подсистемы работник медицинского учреждения сможет регистрировать новых пациентов, заносить их в общую базу, назначать прием, формировать отчеты, а также отображать информацию в цифровом виде на экране монитора, а также в бумажном печатном виде
Currently, the Russian Federation is conducting a general medical examination of the adult population. Clinical examination and clinical observation are necessary for prevention, early detection and further qualified treatment of chronic non-infectious diseases. All chronic diseases develop gradually and not out of nowhere. Conditions that make the disease more likely to occur are called risk factors. Risk factors can be identified long before the first symptoms of the disease appear, and their correction can significantly reduce and even completely prevent the development of the disease. In addition, identifying these factors is much easier and cheaper than later diagnosing and treating an already developed disease. In addition, identifying the disease in the early stages of its development allows treatment to be carried out much faster and more effectively and even to achieve complete recovery. To develop a subsystem for clinical observation, a contextual activity diagram and decomposition diagrams, class diagrams were built, and a structured database was developed. Using this subsystem, a healthcare worker will be able to register new patients, enter them into a common database, make appointments, generate reports, and display information digitally on a monitor screen, as well as in printed paper form
EVALUATION OF CORROSIVENESS OF LES-01 WATER ADDITIVE
Authors: Нелюбов В.Н. , Устрехов А.И. , Копылов Н.П. , Сушкина Е.Ю. 
Published: May 2024

Для тушения лесных пожаров предлагаются различные добавки к воде. Среди них наибольшим огнетушащим эффектом обладает добавка «Лес-01». Исследована коррозионная активность водного раствора «Лес-01» (2,5 % (об.)) и выработаны рекомендации по его безопасному применению как для штатной пожарной техники, так и для авиации.
Various water additives are available for extinguishing forest fires. The additive Les-01 has the most extinguishing effect among them. The corrosiveness of Les-01 water solution (2.5 % vol.) was investigated. There were developed the recommendations for its safe use for both regular fire-fighting equipment and aviation.
Seguridad y Privacidad en el Tiempo Digital, la Era de la Información Liquida
Authors: Mendivelso Jiménez Jesús 
Published: May 2024

Este escrito hace parte de la tesis doctoral titulada: Reconocimiento del derecho a la inclusión digital en Colombia; elaborada por este mismo autor. El propósito de este artículo de revisión bibliográfica, cuya realización corresponde a la metodología descriptiva, con la que se pretende generar conocimiento acerca de la temática de seguridad y privacidad en la era digital, en el tiempo de la denominada información liquida, de la vigilancia panóptica en la que se menoscaba el derecho a la privacidad, esta prerrogativa que es de vieja data, pero que hoy revive su importancia debido a la alta afluencia informativa proveniente de los diversos medios comunicativos y de almacenamiento tecnológico. Puede decirse que, así como fluye la información también va fluyendo la preocupación y el deseo de saber como se protege normativamente la privacidad presente en datos personales, en este nuestro tiempo digital, la era de la información liquida, de la vigilancia panóptica que describió Bentham, que se halla presente en la construcción aldeana de Castell, de la interconexión comunicativa e informativa global.
Caso DIIE-BUAP: Formación de Docentes e Investigadores
Authors: Gutiérrez Gutiérrez Benjamín 
Published: May 2024

El presente estudio analizó cómo el programa de Doctorado en Investigación e Innovación Educativa (DIIE) ha afectado la formación docente-investigativa de los graduados. De acuerdo con la experiencia de Elías-Hardy (2019) en una investigación sobre la gestión de la formación y el desarrollo de expertos en un centro de investigación, se implementaron modificaciones al sistema para adaptarlo a las actividades de los docentes-investigadores en instituciones de educación superior.
Two Distinct Classes of Quiescent Galaxies at Cosmic Noon Revealed by JWST PRIMER and UNCOVER
Authors: Cutler Sam E. , Whitaker Katherine E. , Weaver John R. , Wang 王 Bingjie 冰洁 , Pan Richard , Bezanson Rachel , Furtak Lukas J. , Labbe Ivo , Leja Joel , Price Sedona H. , Cheng Yingjie , Clausen Maike , Cullen Fergus , Dayal Pratika , de Graaff Anna , Dickinson Mark , Dunlop James S. , Feldmann Robert , Franx Marijn , Giavalisco Mauro , Glazebrook Karl , Greene Jenny E. , Grogin Norman A. , Illingworth Garth , Koekemoer Anton M. , Kokorev Vasily , Marchesini Danilo , Maseda Michael V. , Miller Tim B. , Nanayakkara Themiya , Nelson Erica J. , Setton David J. , Shipley Heath , Suess Katherine A. 
Published: May 2024

Abstract
We present a measurement of the low-mass quiescent size–mass relation at cosmic noon (1 < z < 3) from the JWST PRIMER and UNCOVER treasury surveys, which highlights two distinct classes of quiescent galaxies. While the massive population is well studied at these redshifts, the low-mass end has been previously underexplored due to a lack of observing facilities with sufficient sensitivity and spatial resolution. We select a conservative sample of low-mass quiescent galaxy candidates using rest-frame UVJ colors and specific star formation rate criteria and measure galaxy morphology in both rest-frame UV/optical wavelengths (F150W) and rest-frame near-infrared (F444W). We confirm an unambiguous flattening of the low-mass quiescent size–mass relation, which results from the separation of the quiescent galaxy sample into two distinct populations at

log
(

M

⋆

/

M

⊙

)
∼
10.3

: low-mass quiescent galaxies that are notably younger and have disky structures, and massive galaxies consistent with spheroidal morphologies and older median stellar ages. These separate populations imply mass quenching dominates at the massive end while other mechanisms, such as environmental or feedback-driven quenching, form the low-mass end. This stellar mass-dependent slope of the quiescent size–mass relation could also indicate a shift from size growth due to star formation (low masses) to growth via mergers (massive galaxies). The transition mass between these two populations also corresponds with other dramatic changes and characteristic masses in several galaxy evolution scaling relations (e.g., star formation efficiency, dust obscuration, and stellar-to-halo mass ratios), further highlighting the stark dichotomy between low-mass and massive galaxy formation.
Recovering Data of an Observation of the Leonids in 1869 from the Lisbon Geophysical Observatory (Portugal)
Authors: Aparicio A. J. P. , Vaquero J. M. 
Published: May 2024

Abstract
The Leonid meteor shower is renowned for its scientific and public interest. In a search for meteorological data from Portuguese stations, records on an observation of the Leonids in 1869 from the Lisbon Geophysical Observatory “Infante Dom Luiz” were found. Given their potential value, a digital version with metadata is provided in the present note (the recovered data are available on doi:10.5281/zenodo.11221019). The observation took place from 9 PM on 1869 November 13 to 6 AM on November 14, local time in Lisbon, with mostly clear skies and 4–5 observers covering completely the sky. They recorded 1980 meteors, noting Zodiacal Light visibility and detailing meteor counts every five minutes.
Synchroa medogensis, a new species of Synchroidae (Coleoptera) from Xizang, China
Authors: Pan Zhao , Wang Shaopeng 
Published: May 2024

Synchroa medogensis, a new species of Synchroidae Lacordaire, 1859, is described and illustrated, based on a single male collected from Mêdog, Xizang, China. This new species is close to S. elongatula Nikitsky, 1999 and S. melanotoides Lewis, 1895, but could be distinguished by the elongated antennae and elytra, the apically narrowed prosternal process and the stout parameres.
The new information of this new species provided in this paper include: description, type information, distribution and comparison amongst S. medogensis sp. nov., S. elongatula and S. melanotoides.
L’Alsace protestante : illusion d’unité, réalités multiples
Authors: Tourtet Raphaël 
Published: May 2024

L’historiographie religieuse régionale a longtemps dressé une ligne de partage entre une Alsace catholique et une Alsace protestante au singulier. Cette division étonne pour l’époque moderne quand on sait la pluralité des protestantismes. L’approche comparative entre les cas microhistoriques de Sainte-Marie-aux-Mines, de Bischwiller et du bailliage de Cleebourg veut questionner l’émergence d’une conscience ou d’une appréhension unitaire des protestants en Alsace dès les XVIIe et XVIIIe siècles. Le pluralisme confessionnel de ces trois espaces est représentatif de la complexité protestante dans la région. L’étude des relations et de la coexistence intra-protestante dans ces espaces souligne comment, malgré une proximité dogmatique, des frontières confessionnelles se dressent entre protestants. Si des ententes et des actions communes semblent émerger timidement dans la seconde moitié du XVIIIe siècle, elles restent circonstanciées en fonction de besoins ou pour la défense des droits confessionnels face aux catholiques. Ces ententes évoquent alors plus une reconnaissance mutuelle entre protestants qu’une fraternité ou une conscience d’unité. Cette dernière semble davantage s’amorcer dans le regard extérieur des autorités sur les protestants d’Alsace à la fin du XVIIIe siècle, sans pour autant gommer les différences internes.
Éclairer l’Assemblée nationale sur les particularités alsaciennes par l’écrit :
Authors: Fischer Daniel 
Published: May 2024

Le comité des droits féodaux de l’Assemblée nationale est fréquemment sollicité à partir de 1789, tout comme le comité diplomatique à partir de 1790, au sujet d’une question alsacienne : celle des princes d’Empire possessionnés en Alsace qui refusent de reconnaître dans leurs États l’abolition des droits seigneuriaux. Johann Peter Stupfel (1725-1795), agent du prince-évêque de Spire, concerné par cette affaire, entend influencer par l’écrit les travaux des députés, et construit l’idée de l’impossibilité du règlement rapide de cette affaire par le versement d’indemnités, aussi généreuses soient-elles. Les imprimés que Stupfel publie anonymement permettent de comprendre comment cette crise politico-diplomatique a suscité la structuration de deux discours antagonistes reposant sur une écriture différente de l’histoire du rattachement de l’Alsace à la France de 1648 à 1789 : celui de l’adhésion et du partage progressif mais désormais irréversible d’un sort commun avec l’ensemble des Français d’un côté et, de l’autre, celui d’irréductibles particularités de l’Alsace, dont la constitution est le fruit de la sédimentation de clauses de traités internationaux et d’un partage équilibré des souverainetés qu’on ne saurait remettre en question.Mots-clés : comité des droits féodaux, comité diplomatique, droit public, traités internationaux, Révolution française.
L’Alsace, une région mobilisée dans la patrimonialisation de la Neustadt
Authors: Blanc-Reibel Cathy 
Published: May 2024

L’histoire de la Neustadt est étroitement liée à l’histoire spécifique de l’Alsace. Construite à partir du Bebauungsplan de 1880 lors du rattachement de l’Alsace à l’Empire allemand, dès son origine, la mise en œuvre de cet ensemble urbain est corrélée à la situation frontalière de Strasbourg, entre France et Allemagne. Cette situation géographique lui a valu, et lui vaut, une attention particulière tout en lui conférant une dimension symbolique. L’ensemble architectural de la Neustadt évolue de facto entre deux nations : l’une qui a mis en œuvre le plan d’urbanisme et l’autre qui a concouru à sa patrimonialisation. Cet article vise à retracer les événements qui ont permis de mettre en valeur cet ensemble urbain, notamment en dressant un parallèle entre la patrimonialisation de cet espace urbain strasbourgeois et l’acceptation de l’histoire de l’Alsace, tant à l’échelle locale, nationale et internationale. En effet, les liens entre l’histoire de l’Alsace et ce patrimoine strasbourgeois sont prégnants, la Neustadt de Strasbourg pouvant être considérée comme une métonymie de l’évolution des relations franco-allemandes.
Invisibles aux yeux de l’État. Une première estimation des « disparitions administratives » en Région de Bruxelles-Capitale
Authors: Moriau Jacques , Malherbe Alain , Sanderson Jean-Paul , Pierre Adèle , Leclercq Alexandre 
Published: May 2024

En Belgique, la domiciliation donne accès aux droits fondamentaux par l’inscription des personnes au Registre National. Le Registre National centralise toutes les données qui sont recueillies par les communes. L’invisibilisation administrative a donc des conséquences directes sur la jouissance des droits sociaux. Elle a trois origines distinctes : l’absence d’inscription, la radiation, la suppression de personnes du Registre National. Au départ de l’analyse des données du Registre National, cet article s’intéresse aux phénomènes d’« invisibilisation administrative », c’est-à-dire à la disparition ou la radiation, volontaire ou involontaire, des registres administratifs. Une analyse anthropologique des pratiques administratives concernant la domiciliation des personnes introduit l’article qui est poursuivi par une quantification et une spatialisation du phénomène d'invisibilisation administrative et enfin une enquête sociologique auprès des personnes victimes d’invisibilisation administrative éclaire leurs parcours d’exclusion.