bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contribution of intrapulmonary artery Doppler to improve prediction of survival in fetuses with congenital diaphragmatic hernia treated with fetal endoscopic tracheal occlusion
Authors: Cruz‐Martinez R. , Moreno‐Alvarez O. , Hernandez‐Andrade E. , Castañon M. , Done E. , Martinez J. M. , Puerto B. , Deprest J. , Gratacos E. 
Published: February 2010

AbstractObjectiveTo evaluate the contribution of intrapulmonary artery Doppler in predicting the survival of fetuses with congenital diaphragmatic hernia (CDH) treated with fetoscopic tracheal occlusion (FETO).MethodsA cohort of 41 fetuses (between 24 and 28 weeks of gestation) with CDH was treated with FETO. The observed/expected lung‐to‐head ratio (O/E‐LHR), pulmonary artery pulsatility index (PI), peak early diastolic reversed flow (PEDRF) and peak systolic velocity (PSV) were evaluated before FETO, and their isolated and combined value to predict survival using multiple logistic regression and decision‐tree analysis was assessed.ResultsO/E‐LHR and intrapulmonary artery PI and PEDRF were significantly associated with the probability of survival (O/E‐LHR ≥ 26%, OR 14.2; PI < 1 Z‐score, OR 8.4; and PEDRF < 3.5Z‐scores, OR 5.7). Decision‐tree analysis showed that O/E‐LHR was the best initial predictor of prognosis (O/E‐LHR ≥ 26%, 90% survival; O/E‐LHR < 26%, 45% survival). For fetuses with an O/E‐LHR of < 26%, Doppler parameters allowed discrimination of cases with moderate (66–71% survival) and very poor (0% survival) prognosis.ConclusionIntrapulmonary artery Doppler evaluation helps to refine the prediction of survival after FETO in fetuses with severe CDH. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Gel instillation sonohysterography (GIS) and saline contrast sonohysterography (SCSH): comparison of two diagnostic techniques
Authors: Bij de Vaate A. J. M. , Brölmann H. A. M. , van der Slikke J. W. , Emanuel M. H. , Huirne J. A. F. 
Published: February 2010

AbstractObjectiveTo compare gel instillation sonohysterography (GIS) with saline contrast sonohysterography (SCSH) as diagnostic methods for the evaluation of the uterine cavity.MethodsA prospective cohort study was performed at the Department of Obstetrics and Gynecology of the VU University Medical Center, Amsterdam, between September 2007 and April 2008. We included 65 women suspected of having an intrauterine abnormality with an indication for SCSH/GIS. First SCSH and subsequently GIS were performed in all women. Distension of the uterine cavity, image quality, visualization of intrauterine abnormalities and pain experienced on a visual analog scale (VAS score) were recorded for both procedures.ResultsThe mean distension with GIS was 9.0 mm and with SCSH it was 8.5 mm (P = 0.15). The mean image quality, on a scale from 0 to 5, for SCSH was 4.0 and for GIS it was 3.6 (P = 0.01). No difference was found for the visualization of intrauterine abnormalities, and the VAS scores for pain experienced on SCSH and GIS were 1.5 and 1.6, respectively (P = 0.62).ConclusionsThe image quality of SCSH is slightly better than that of GIS. This difference is likely to be attributable to the presence of air bubbles in the gel. The small difference in uterine cavity distension in favor of GIS and comparable stable distension during at least 4 min make GIS a suitable alternative for SCSH if air bubbles can be prevented. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Surface and Self‐Aggregation Properties of Bis‐Benzimidazolones Derivatives of d‐Glucose
Authors: Lakhrissi Brahim , Lakhrissi Loubna , Massoui Mohamed , Essassi El Mokhtar , Comelles Francesc , Esquena Jordi , Solans Conxita , Rodríguez‐Abreu Carlos 
Published: February 2010

AbstractThe surface and self‐aggregation properties in water of a new series of amphiphilic homologues, bis‐benzimidazolone derivatives of d‐glucose, were investigated. Parameters such as the maximal surface excess concentration, minimal area per molecule at the interface, and critical micelle concentration (CMC) were found to be significantly dependent on the hydrophobic alkyl chain length. The synthesized compounds form micelles at remarkably low concentrations, and CMCs derived from surface tension measurements show a minimum as a function of the alkyl chain length; this unusual trend can be attributed to the formation of submicellar aggregates in compounds with long alkyl chains, as evidenced from fluorescence probe spectroscopy data. At high surfactant concentrations, lyotropic liquid crystalline phases with hexagonal structure are formed. Small angle X‐ray scattering measurements indicate that the characteristic nanoscopic lengths increase with water swelling and alkyl chain length.
Mental health problems during puberty: Tanner stage‐related differences in specific symptoms. The TRAILS study
Authors: Oldehinkel Albertine J. , Verhulst Frank C. , Ormel Johan 
Published: February 2010

ABSTRACTThe aim of this study was to investigate associations between specific mental health problems and pubertal stage in (pre)adolescents participating in the Dutch prospective cohort study TRAILS (first assessment:N= 2230, age 11.09 ± 0.56, 50.8% girls; second assessment:N= 2149, age 13.56 ± 0.53, 51.0% girls). Mental health was assessed by the Youth Self‐Report, pubertal (Tanner) stage by parent‐rated drawings of secondary sex characteristics. Overall, higher Tanner stages were related to more reported tiredness, irritability, rule‐breaking behaviors, and substance use; and fewer fears and somatic complaints. Girls showed increases in social uncertainty, depressed mood, and worries; boys a decrease in self‐criticism. Increasing problems during puberty were mostly related to the process of physical maturation, whereas decreasing problems were rather related to general age‐related developments. Pubertal timing was associated with different symptoms than pubertal status or age. Puberty seems to affect girls more negatively than boys.
Mosquito density forecast from flooding: population dynamics model forAedes caspius(Pallas)
Authors: Balenghien T. , Carron A. , Sinègre G. , Bicout D.J. 
Published: February 2010

AbstractInsect population dynamics depend strongly on environmental factors. For floodwater mosquitoes, meteorological conditions are crucial in the rhythm of mosquito abundances. Indeed, rainfall triggers the egg hatching after flooding breeding sites, and temperature controls the duration of the aquatic immature development up to adult emergence.According to this, we have developed a simple mechanistic and tractable model that describes the population dynamics of floodwater mosquitoes as a function only of the most accessible meteorological variables, rainfall and temperature. The model involves three parameters: development durationtdevof the immature aquatic stages, the adult emergence rate functionf(t) (characterized by the emergence time scale τ and shaping the profile of adult population abundance), and the depletion rate, α, of adult disappearance.The developed model was subsequently applied to fit experimental field data of the dynamics ofAedes caspius(Pallas), the main pest mosquito in southern France. First, it was found that the emergence rate function of adult mosquitoes very well reproduce experimental data of the dynamics of immature development for all sampled temperatures. The estimated values oftdevand τ both exhibit Arrhenius behaviour as a function of temperature. Second, using the meteorological records of rainfall and temperature as inputs, the model correctly fit data from a two-site CO2trapping survey conducted in 2004 and 2005. The estimated depletion rates (summation of the mortality and the emigration rates) were found to be a concave quadratic function of temperature with a maximum of 0.5 per days at about 22°C.
Seroprevalence ofCysticercus cellulosaeand associated risk factors in free-range pigs in Kenya
Authors: Kagira J.M. , Maingi N. , Kanyari P.W.N. , Githigia S.M. , Ng'ang'a J.C. , Gachohi J.M. 
Published: February 2010

AbstractPorcine cysticercosis is an emerging zoonosis with public health and economic importance. A cross-sectional study was undertaken to investigate the disease in free-range pigs on 182 smallholder farms in Busia District, Kenya. The survey households were selected using a snowballing technique. Serum samples were obtained from 284 pigs of all ages at farm level and 37 pigs from slaughter slabs in the study area. The samples were analysed for the presence of cysticercus antigen using an antigen enzyme-linked immunosorbent assay (ELISA). A structured questionnaire was administered to determine the risk factors for porcine cysticercosis on the study farms. At pig level, the total number of pigs testing positive were 11, resulting in a seroprevalence of 4% (95% confidence interval (CI): 1.9–6.2%), while the farms with a positive pig were 9% (95% CI: 3.9–14.1%). All pigs examined in the slaughter slab survey were seronegative. The distribution of possible risk factors for porcine cysticercosis that were observed at farm level was as follows: free-range pig keeping (100%), history of human taeniosis infection in a family (51%), slaughtering of pigs at home (20%), lack of meat inspection (15%) and absence of latrines (15%). The only significant (χ2 = 4.4,P = 0.034, odds ratio (OR) = 3.8) risk factor associated with the occurrence of cysticercosis was lack of latrines at household level. The study shows that porcine cysticercosis is prevalent in free-range pigs in Busia District, Kenya and thus control measures need to be instituted.
Bilateral hearing results of 751 unilateral stapedotomies evaluated with the Glasgow benefit plot
Authors: Kisilevsky V , Bailie N A , Halik J J 
Published: February 2010

AbstractAims:We aimed to evaluate bilateral hearing function in patients undergoing primary unilateral stapedotomy, according to the 1995 American Academy of Otolaryngology, Head and Neck Surgery guidelines and the Glasgow benefit plot. We also aimed to analyse the effect of pre-operative hearing impairment type on post-stapedotomy hearing.Study design:Retrospective chart review.Methods:Medical records relating to 1369 stapedotomies performed by the senior author (JJH) from 1991 to 2006 were reviewed. Seven hundred and fifty-one patients undergoing primary unilateral stapedotomy were included. Hearing results for these patients were evaluated according to the criteria of the 1995 American Academy of Otolaryngology, Head and Neck Surgery Committee on Hearing and Equilibrium guidelines, and the Glasgow benefit plot. Subgroups of patients with pre-operative unilateral, bilateral symmetrical and bilateral asymmetrical hearing loss were separately analysed.Results:The most successful results, as regards the achievement of bilateral, socially serviceable hearing, were demonstrated in patients with unilateral hearing loss; 78 per cent of these patients had normal hearing post-operatively. Overall, patients' achievement of bilateral, socially serviceable hearing correlated highly with their type of pre-operative hearing impairment (r = 0.74). Normal post-operative hearing levels also correlated with pre-operative bone conduction (r = 0.61).Conclusion:This study represents the largest reported series of primary stapedotomy cases evaluated with the Glasgow benefit plot. Patients' bilateral post-operative hearing function depended on their type of pre-operative hearing impairment. Pre-operative bone conduction thresholds, corrected for Carhart's effect, were useful in predicting achievable post-operative air conduction.
L'emploi préludique de l'imparfait entre temporalité et modalité: Éléments d'analyse à partir d'une étude de cas
Authors: PATARD ADELINE 
Published: February 2010

ABSTRACTCet article constitue une tentative d'analyse d'un emploi peu étudié de l'imparfait – l'imparfait préludique – tel qu'il a été observé dans les énoncés authentiques prononcés par une petite fille en situation de jeu. À partir de la description du contexte ainsi que du co-texte, nous essayons d'expliquer en quoi la valeur aspectuo-temporelle de l'imparfait répond parfaitement aux contraintes linguistiques et situationnelles de cet usage; puis de mieux comprendre les raisons de cet emploi chez l'enfant observé en évaluant tour à tour deux hypothèses proposées dans la littérature (reality-switchingouself-effacement) pour rendre compte de l'effet modal produit par l'imparfait dans ce tour.
Acute and long-term effects of grape and pomegranate juice consumption on vascular reactivity in paediatric metabolic syndrome
Authors: Hashemi Mohammad , Kelishadi Roya , Hashemipour Mahin , Zakerameli Afshin , Khavarian Noushin , Ghatrehsamani Shohreh , Poursafa Parinaz 
Published: February 2010

AbstractObjectivesThis study, which to the best of our knowledge is the first of its kind, aimed to determine the acute and long-term effects of the consumption of grape and pomegranate juices on endothelium function in adolescents with metabolic syndrome, and to compare the effects of these two kinds of juices.MethodsThis randomised controlled clinical trial was conducted in 2008 among 30 adolescents, aged 12–15 years, with metabolic syndrome. Participants were randomly assigned to two groups of equal number; one group was asked to drink 18 millilitre per kilogram per day of natural grape juice and the other group was asked to drink 240 millilitre per day of natural pomegranate juice once daily for 1 month. Juices were homemade without any added sweetener. Basal brachial artery dimension and flow-mediated dilation as an index of endothelial function and endothelial-dependent dilation after receiving nitoglycerin spray were evaluated by high-resolution B mode ultrasonography before juice consumption, 4 hours and 30 days after regular daily consumption.ResultsFlow-mediated dilation at 90 seconds and after nitoglycerin significantly improved at 4 hours and at 1 month after drinking both kinds of juices, without significant difference between the two groups. The change at 1 month versus 4 hours was significant only in the grape juice group.ConclusionDaily consumption of diets rich in antioxidants might improve endothelial function in adolescents with metabolic syndrome. These effects began as soon as 4 hours after juice consumption. Such beneficial effects should be considered in dietary recommendations for the paediatric age group, notably in obese individuals.
Profiles of functional deficits in mild cognitive impairment and dementia: benefits from objective measurement
Authors: PEREIRA FERNANDA SPEGGIORIN , YASSUDA MÔNICA SANCHES , OLIVEIRA ALEXANDRA MARTINI , DINIZ BRENO SATLER , RADANOVIC MÁRCIA , TALIB LEDA LEME , GATTAZ WAGNER FARID , FORLENZA ORESTES VICENTE 
Published: February 2010

AbstractThe magnitude of functional impairment that may indicate the threshold between MCI and incipient Alzheimer’s disease (AD) has not been clearly defined. The objective was to examine the pattern of functional impairment in the continuum MCI-AD. Eighty-nine older adults (32 cognitively unimpaired, 31 MCI, and 26 AD patients) were examined with the Brazilian version of the Direct Assessment of Functional Status (DAFS-BR) at a university-based memory clinic. MCI patients were sub-divided according to the progression to AD upon follow-up, and had baseline cognitive, functional and biological variables analyzed. MCI patients displayed mild deficits in functional abilities, with intermediate scores as compared to controls and AD. The DAFS-BR items that differentiated MCI from controls involved the ability to deal with finances and shopping skills. At baseline, scores obtained by MCI patients who converted to AD were not significantly different from scores of nonconverters. The magnitude of functional deficits was associated with AD-like pathological findings in the CSF. In conclusion, MCI patients present with early functional changes in complex, instrumental abilities that require the integrity of memory and executive functions. The objective measurement of the functional state may help identify older adults with increased risk of developing dementia in the MCI-AD continuum. (JINS, 2010, 16, 297–305.)
Learning and memory in amnestic mild cognitive impairment: Contribution of working memory
Authors: PRICE SARAH E. , KINSELLA GLYNDA J. , ONG BEN , MULLALY ELIZABETH , PHILLIPS MARGARET , PANGNADASA-FOX LANKI , PERRE DIANA , STOREY ELSDON 
Published: February 2010

AbstractIn addition to deficits in delayed recall, recent research suggests that participants with amnestic mild cognitive impairment (aMCI) demonstrate diminished use of strategic encoding strategies during learning. Few studies have explored the cognitive mechanisms underlying this deficit. The aim of this study was to investigate in aMCI whether components of working memory (executive attention – attention set-shifting, dividing and focusing attention; and episodic buffer functions – strategic retrieval and manipulation of information) predict strategic encoding strategies during learning (semantic clustering). Thirty-three participants with aMCI and 33 healthy older adults (HOA) were administered neuropsychological tests assessing word-list learning and working memory. The aMCI group demonstrated significant impairment in acquisition, retrieval of information, and decreased use of semantic clustering strategies. Use of semantic clustering in the aMCI group was not predicted by measures of executive attention or phonemic verbal fluency, but was predicted by semantic verbal fluency performance. In the HOA group, semantic clustering was strongly related to semantic verbal fluency. These findings suggest that in aMCI, diminished strategic encoding strategies during learning (semantic clustering) is selectively related to the strategic function of the episodic buffer, but only when in interaction with the manipulation and retrieval of semantic associations. (JINS, 2010, 16, 342–351.)
A Time-Series Analysis of Clostridium difficile and Its Seasonal Association with Influenza
Authors: Polgreen Philip M. , Yang Ming , Bohnett Lucas C. , Cavanaugh Joseph E. 
Published: February 2010

Objective.To characterize the temporal progression of the monthly incidence of Clostridium difficile infections (CDIs) and to determine whether the incidence of CDI is related to the incidence of seasonal influenza.Design.A retrospective study of patients in the Nationwide Inpatient Sample during the period from 1998 through 2005.Methods.We identified all hospitalizations with a primary or secondary diagnosis of CDI with use of International Classification of Diseases, 9th Revision, Clinical Modification codes, and we did the same for influenza. The incidence of CDI was modeled as an autoregression about a linear trend. To investigate the association of CDI with influenza, we compared national and regional CDI and influenza series data and calculated cross-correlation functions with data that had been prewhitened (filtered to remove temporal patterns common to both series). To estimate the burden of seasonal CDI, we developed a proportional measure of seasonal CDI.Results.Time-series analysis of the monthly number of CDI cases reveals a distinct positive linear trend and a clear pattern of seasonal variation (R2 = 0.98). The cross-correlation functions indicate that influenza activity precedes CDI activity on both a national and regional basis. The average burden of seasonal (ie, winter) CDI is 23%.Conclusions.The epidemiologic characteristics of CDI follow a pattern that is seasonal and associated with influenza, which is likely due to antimicrobial use during influenza seasons. Approximately 23% of average monthly CDI during the peak 3 winter months could be eliminated if CDI remained at summer levels.
Use of Central Venous Catheter and Peripheral Venous Catheter as Risk Factors for Nosocomial Bloodstream Infection in Very-Low-Birth-Weight Infants
Authors: Geffers Christine , Gastmeier Anne , Schwab Frank , Groneberg Katrin , Rüden Henning , Gastmeier Petra 
Published: February 2010

Objective.To describe the relationship between the use of central and peripheral venous catheters and the risk of nosocomial, primary, laboratory-confirmed bloodstream infection (BSI) for neonates with a birth weight less than 1,500 g (very-low-birth-weight [VLBW] infants).Methods.Cox proportional hazard regression analysis with time-dependent variable was used to determine the risk factors for the occurrence of BSI in a cohort of VLBW infants. We analyzed previously collected surveillance data from the German national nosocomial surveillance system for VLBW infants. All VLBW infants in 22 participating neonatal departments who had a complete daily record of patient information were included.Results.Of 2,126 VLBW infants, 261 (12.3%) developed a BSI. The incidence density for BSI was 3.3 per 1,000 patient-days. The multivariate analysis identified the following significant independent risk factors for BSI: lower birth weight (hazard ratio [HR], 1.1–2.2), vaginal delivery (HR, 1.5), central venous catheter use (HR, 6.2) or peripheral venous catheter use (HR, 6.0) within 2 days before developing BSI, and the individual departments (HR, 0.0–4.6).Conclusions.After adjusting for other risk factors, use of peripheral venous catheter and use of central venous catheter were significantly related to occurrence of BSI in VLBW infants.
Natural History of Colonization with Gram-Negative Multidrug-Resistant Organisms among Hospitalized Patients
Authors: Weintrob Amy C. , Roediger Mollie P. , Barber Melissa , Summers Amy , Fieberg Ann M. , Dunn James , Seldon Venus , Leach Fluryanne , Huang Xiao-Zhe , Nikolich Mikeljon P. , Wortmann Glenn W. 
Published: February 2010

Objective.To determine the anatomic sites and natural history of colonization with gram-negative multidrug-resistant organisms (MDROs).Design.Prospective, longitudinal cohort study.Setting.Walter Reed Army Medical Center, a 236-bed tertiary care center in Washington, DC.Patients.Deployed subjects (ie, inpatients medically evacuated from Iraq or Afghanistan) or nondeployed subjects admitted to the same hospital.Methods.Consenting patients had 6 anatomic sites cultured every 3 days for 2 weeks and then weekly. Gram-negative organisms resistant to 3 or more classes of antibiotics were considered MDROs. Isolates were genotyped using pulsed-field gel electrophoresis. Clinical data, data on antibiotic use, and clinical culture results were collected.Results.Of 60 deployed subjects, 14 (23%) were colonized with an MDRO at admission, and 13 (22%) had incident colonization during hospitalization. The groin was the most sensitive anatomic site for detecting MDRO colonization, and all but one subject remained colonized for the duration of their hospitalization. Sixty percent of subjects with incident Acinetobacter colonization and 25% of subjects with incident Klebsiella colonization had strains that were related to those isolated from other subjects. Of 60 nondeployed subjects, 5 (8%) were colonized with an MDRO at admission; all had recent healthcare contact, and 1 nondeployed subject had an isolate related to a strain recovered from a deployed subject.Conclusions.Colonization with gram-negative MDROs is common among patients with war-related trauma admitted to a military hospital and also occurs among nondeployed patients with recent healthcare contact. The groin is the most sensitive anatomic site for active surveillance, and spontaneous decolonization is rare.
Microbe–dendritic cell dialog controls regulatory T‐cell fate
Authors: Grainger John R. , Hall Jason A. , Bouladoux Nicolas , Oldenhove Guillaume , Belkaid Yasmine 
Published: February 2010

Summary:Each microenvironment is controlled by a specific set of regulatory elements that have to be finely and constantly tuned to maintain local homeostasis. These environments could be site specific, such as the gut environment, or induced by chronic exposure to microbes. Various populations of dendritic cells are central to the orchestration of this control. In this review, we discuss some new findings associating dendritic cells from defined compartments with the induction and control of regulatory T cells in the context of exposure to both commensal and pathogenic microbes.