bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brain Network Dynamics Underlying Visuospatial Judgment: An fMRI Connectivity Study
Authors: de Graaf Tom A. , Roebroeck Alard , Goebel Rainer , Sack Alexander T. 
Published: October 2009

Abstract
Previous functional imaging research has consistently indicated involvement of bilateral fronto-parietal networks during the execution of visuospatial tasks. Studies with TMS have suggested that the right hemispheric network, but not the left, is functionally relevant for visuospatial judgments. However, very little is still known about the interactions within these fronto-parietal networks underlying visuospatial processing. In the current study, we investigated task modulation of functional connectivity (instantaneous correlations of regional time courses), and task-specific effective connectivity (direction of influences), within the right fronto-parietal network activated during visuospatial judgments. Ten healthy volunteers performed a behaviorally controlled visuospatial judgment task (ANGLE) or a control task (COLOR) in an fMRI experiment. Visuospatial task-specific activations were found in posterior parietal cortex (PPC) and middle/inferior frontal gyrus (MFG). Functional connectivity within this network was task-modulated, with significantly higher connectivity between PPC and MFG during ANGLE than during COLOR. Effective connectivity analysis for directed influence revealed that visuospatial task-specific projections within this network were predominantly in a frontal-to-parietal direction. Moreover, ANGLE-specific influences from thalamic nuclei to PPC were identified. Exploratory effective connectivity analysis revealed that closely neighboring clusters, within visuospatial regions, were differentially involved in the network. These neighboring clusters had opposite effective connectivity patterns to other nodes of the fronto-parietal network. Our data thus reveal that visuospatial judgments are supported by massive fronto-parietal backprojections, thalamo-parietal influence, and multiple stages, or loops, of information flow within the visuospatial network. We speculate on possible functional contributions of the various network nodes and informational loops in a neurocognitive model.
Heterogeneous Structure in Face-selective Human Occipito-temporal Cortex
Authors: Betts Lisa R. , Wilson Hugh R. 
Published: October 2009

Abstract
It is well established that the human visual system contains a distributed network of regions that are involved in processing faces, but our understanding of how faces are represented within these face-sensitive brain areas is incomplete. We used fMRI to investigate whether face-sensitive brain areas are solely tuned for whole faces, or whether they contain heterogeneous populations of neurons tuned to individual components of the face as well as whole faces, as suggested by physiological investigations in nonhuman primates. The middle fusiform gyrus (fusiform face area, or FFA) and the inferior occipital gyrus (occipital face area, or OFA) produced robust BOLD activation to synthetic whole face stimuli, but also to the internal facial features and head outlines. BOLD responses to whole face stimuli in FFA were significantly reduced after adaptation to whole faces, but not after adaptation to features or head outlines, whereas activation to head outlines was reduced after adaptation to both whole faces and head outlines. OFA showed no significant adaptation effects for matching adaptation and test conditions, but did exhibit cross-adaptation between whole faces and head outlines. The internal face features did not produce any significant adaptation within either FFA or OFA. Our results are consistent with a model in which independent populations of whole face-, feature-, and head outline-tuned neurons exist within face-sensitive regions of human occipito-temporal cortex, which in turn would support tasks such as viewpoint processing, emotion classification, and identity discrimination.
Electrophysiological Evidence of Semantic Interference in Visual Search
Authors: Telling Anna L. , Kumar Sanjay , Meyer Antje S. , Humphreys Glyn W. 
Published: October 2009

Abstract
Visual evoked responses were monitored while participants searched for a target (e.g., bird) in a four-object display that could include a semantically related distractor (e.g., fish). The occurrence of both the target and the semantically related distractor modulated the N2pc response to the search display: The N2pc amplitude was more pronounced when the target and the distractor appeared in the same visual field, and it was less pronounced when the target and the distractor were in opposite fields, relative to when the distractor was absent. Earlier components (P1, N1) did not show any differences in activity across the different distractor conditions. The data suggest that semantic distractors influence early stages of selecting stimuli in multielement displays.
Dissociable Roles of the Anterior Temporal Regions in Successful Encoding of Memory for Person Identity Information
Authors: Tsukiura Takashi , Mano Yoko , Sekiguchi Atsushi , Yomogida Yukihito , Hoshi Kaori , Kambara Toshimune , Takeuchi Hikaru , Sugiura Motoaki , Kawashima Ryuta 
Published: October 2009

Abstract
Memory for person identity information consists of three main components: face-related information, name-related information, and person-related semantic information, such as the person's job title. Although previous studies have demonstrated the importance of the anterior temporal lobe (ATL) in the retrieval of associations between these kinds of information, there is no evidence concerning whether the ATL region contributes to the encoding of this memory, and whether ATL roles are dissociable between different levels of association in this memory. Using fMRI, we investigated dissociable roles within the ATL during successful encoding of this memory. During encoding, participants viewed unfamiliar faces, each paired with a job title and name. During retrieval, each learned face was presented with two job titles or two names, and participants were required to choose the correct job title or name. Successful encoding conditions were categorized by subsequent retrieval conditions: successful encoding of names and job titles (HNJ), names (HN), and job titles (HJ). The study yielded three main findings. First, the dorsal ATL showed greater activations in HNJ than in HN or HJ. Second, ventral ATL activity was greater in HNJ and HJ than in HN. Third, functional connectivity between these regions was significant during successful encoding. The results are the first to demonstrate that the dorsal and ventral ATL roles are dissociable between two steps of association, associations of person-related semantics with name and with face, and a dorsal–ventral ATL interaction predicts subsequent retrieval success of memory for person identity information.
Optimizing Design Efficiency of Free Recall Events for fMRI
Authors: Öztekin Ilke , Long Nicole M. , Badre David 
Published: October 2009

Abstract
Free recall is a fundamental paradigm for studying memory retrieval in the context of minimal cue support. Accordingly, free recall has been extensively studied using behavioral methods. However, the neural mechanisms that support free recall have not been fully investigated due to technical challenges associated with probing individual recall events with neuroimaging methods. Of particular concern is the extent to which the uncontrolled latencies associated with recall events can confer sufficient design efficiency to permit neural activation for individual conditions to be distinguished. The present study sought to rigorously assess the feasibility of testing individual free recall events with fMRI. We used both theoretically and empirically derived free recall latency distributions to generate simulated fMRI data sets and assessed design efficiency across a range of parameters that describe free recall performance and fMRI designs. In addition, two fMRI experiments empirically assessed whether differential neural activation in visual cortex at onsets determined by true free recall performance across different conditions can be resolved. Collectively, these results specify the design and performance parameters that can provide comparable efficiency between free recall designs and more traditional jittered event-related designs. These findings suggest that assessing BOLD response during free recall using fMRI is feasible, under certain conditions, and can serve as a powerful tool in understanding the neural bases of memory search and overt retrieval.
Contributions of Spatial Working Memory to Visuomotor Learning
Authors: Anguera Joaquin A. , Reuter-Lorenz Patricia A. , Willingham Daniel T. , Seidler Rachael D. 
Published: October 2009

Abstract
Previous studies of motor learning have described the importance of cognitive processes during the early stages of learning; however, the precise nature of these processes and their neural correlates remains unclear. The present study investigated whether spatial working memory (SWM) contributes to visuomotor adaptation depending on the stage of learning. We tested the hypothesis that SWM would contribute early in the adaptation process by measuring (i) the correlation between SWM tasks and the rate of adaptation, and (ii) the overlap between the neural substrates of a SWM mental rotation task and visuomotor adaptation. Participants completed a battery of neuropsychological tests, a visuomotor adaptation task, and an SWM task involving mental rotation, with the latter two tasks performed in a 3.0-T MRI scanner. Performance on a neuropsychological test of SWM (two-dimensional mental rotation) correlated with the rate of early, but not late, visuomotor adaptation. During the early, but not late, adaptation period, participants showed overlapping brain activation with the SWM mental rotation task, in right dorsolateral prefrontal cortex and the bilateral inferior parietal lobules. These findings suggest that the early, but not late, phase of visuomotor adaptation engages SWM processes.
The Role of the Left Head of Caudate in Suppressing Irrelevant Words
Authors: Ali Nilufa , Green David W. , Kherif Ferath , Devlin Joseph T. , Price Cathy J. 
Published: October 2009

Abstract
Suppressing irrelevant words is essential to successful speech production and is expected to involve general control mechanisms that reduce interference from task-unrelated processing. To investigate the neural mechanisms that suppress visual word interference, we used fMRI and a Stroop task, using a block design with an event-related analysis. Participants indicated with a finger press whether a visual stimulus was colored pink or blue. The stimulus was either the written word “BLUE,” the written word “PINK,” or a string of four Xs, with word interference introduced when the meaning of the word and its color were “incongruent” (e.g., BLUE in pink hue) relative to congruent (e.g., BLUE in blue) or neutral (e.g., XXXX in pink). The participants also made color decisions in the presence of spatial interference rather than word interference (i.e., the Simon task). By blocking incongruent, congruent, and neutral trials, we identified activation related to the mechanisms that suppress interference as that which was greater at the end relative to the start of incongruency. This highlighted the role of the left head of caudate in the control of word interference but not spatial interference. The response in the left head of caudate contrasted to bilateral inferior frontal activation that was greater at the start than at the end of incongruency, and to the dorsal anterior cingulate gyrus which responded to a change in the motor response. Our study therefore provides novel insights into the role of the left head of caudate in the mechanisms that suppress word interference.
Graded Effects of Regularity in Language Revealed by N400 Indices of Morphological Priming
Authors: Kielar Aneta , Joanisse Marc F. 
Published: October 2009

Abstract
Differential electrophysiological effects for regular and irregular linguistic forms have been used to support the theory that grammatical rules are encoded using a dedicated cognitive mechanism. The alternative hypothesis is that language systematicities are encoded probabilistically in a way that does not categorically distinguish rule-like and irregular forms. In the present study, this matter was investigated more closely by focusing specifically on whether the regular–irregular distinction in English past tenses is categorical or graded. We compared the ERP priming effects of regulars (baked–bake), vowel-change irregulars (sang–sing), and “suffixed” irregulars that display a partial regularity (suffixed irregular verbs, e.g., slept–sleep), as well as forms that are related strictly along formal or semantic dimensions. Participants performed a visual lexical decision task with either visual (Experiment 1) or auditory prime (Experiment 2). Stronger N400 priming effects were observed for regular than vowel-change irregular verbs, whereas suffixed irregulars tended to group with regular verbs. Subsequent analyses decomposed early versus late-going N400 priming, and suggested that differences among forms can be attributed to the orthographic similarity of prime and target. Effects of morphological relatedness were observed in the later-going time period, however, we failed to observe true regular–irregular dissociations in either experiment. The results indicate that morphological effects emerge from the interaction of orthographic, phonological, and semantic overlap between words.
Cannabinoid Modulations of Resting State EEG Theta Power and Working Memory Are Correlated in Humans
Authors: Böcker Koen B. E. , Hunault Claudine C. , Gerritsen Jeroen , Kruidenier Maaike , Mensinga Tjeert T. , Kenemans J. Leon 
Published: October 2009

Abstract
Object representations in working memory depend on neural firing that is phase-locked to oscillations in the theta band (4–8 Hz). Cannabis intake disrupts synchronicity of theta oscillations and interferes with memory performance. Sixteen participants smoked cigarettes containing 0.0, 29.3, 49.1, or 69.4 mg Δ9-tetrahydrocannabinol (THC) in a randomized crossover design and performed working memory and general attention tasks. Dose-dependent effects of THC were observed for resting state EEG theta and beta power, working memory (per-item search time), and attentional performance (percent errors and RT). The THC effects on EEG theta power and memory performance were correlated, whereas other EEG and behavioral effects were not. These findings confirm and extend previous results in rodents and humans, and corroborate a neurocomputational model that postulates that temporal aspects of information processing in working memory depend causally on nested oscillations in the theta and gamma (&gt;30 Hz) bands.
Hemispheric Asymmetry in the Remapping and Maintenance of Visual Saliency Maps: A TMS Study
Authors: van Koningsbruggen Martijn Gerbrand , Gabay Shai , Sapir Ayelet , Henik Avishai , Rafal Robert D. 
Published: October 2009

Abstract
Parietal cortex has been implicated in the updating, after eye movements, of a salience map that is required for coherent visual experience and for the control of visually guided behavior. The current experiment investigated whether TMS over anterior intraparietal cortex (AIPCx), just after a saccade, would affect the ability to update and maintain a salience map. In order to generate a salience map, we employed a paradigm in which an uninformative cue was presented at one object in a display to generate inhibition of return (IOR)—an inhibitory tag that renders the cued object less salient than others in the display, and that slows subsequent responses to visual transients at its location. Following the cue, participants made a saccade to either left or right, and we then probed for updating of the location of IOR by measuring manual reaction time to targets appearing at cued location of the cued compared to an uncued object. Between the time of saccade initiation and target appearance, dual-pulse TMS was targeted over right (Experiment 1) or left AIPCx (Experiment 2), and a vertex control side. Updating of the location of IOR was eliminated by TMS over right, but not the left, AIPCx, suggesting that right parietal cortex is involved in the remapping of IOR. Remapping was eliminated by right AIPCx, regardless of whether the saccade was made to the left (contralateral), or right (ipsilateral) visual field, and regardless of which field the target appeared in. We conclude that right AIPCx is the neural substrate for maintaining a salience map across saccades, and not simply for propagating an efference copy of saccade commands.
Thebes Revisited: Theodicy and the Temporality of Evil
Authors: Manoussakis John Panteleimon 
Published: October 2009

AbstractThis essay gives a close reading of Sophocles' Oedipus Rex in light of Schelling's discussion of theodicy as teleology. The article raises the question of the connection between ethics and time, and it argues that ethical categories are really temporal ones, so much so that it would make little sense to posit a choice between good and evil as if there were two simultaneous options. Instead, the story of Oedipus shows us how Thebes is always to precede if one is to reach Colonus, that evil precedes and enables the good.
Careers in the Dutch civil service: a gender perspective
Authors: Groeneveld Sandra 
Published: October 2009

This article focuses upon gender differences in the satisfaction with career opportunities of civil servants in the Netherlands. Women have become better represented at all levels in the Dutch civil service in recent years, but they are still underrepresented in the higher level positions. Nevertheless, women are slightly more satisfied with their career opportunities than men are and they seem to be increasingly so. Their relatively positive evaluation of extrinsic aspects of their work situation is one of the explanations of this finding, as is their higher intrinsic work motivation compared to that of men. It is suggested that the career orientations and aspirations of women better fit the changing context of career formation in the Dutch civil service and the accompanying new psychological contract.Points for practitionersThe Dutch civil service has set ambitious targets with respect to the representation of women at all levels in the service, but insight into the determinants of women’s careers in the public sector is still very scarce. The findings in this article show that there are gender differences in the weighting of intrinsic and extrinsic aspects of the work in evaluating one’s career opportunities. Besides, the article may assist human resource management practitioners in anticipating the impact of changing career trajectories on the career satisfaction of male and female civil servants.
Contextualizing the Dutch drop in political trust: connecting underlying factors
Authors: Hendriks Frank 
Published: October 2009

How can it be that a country — one that was envied until the very end of the twentieth century for its enduring high level of trust in the political system — could have suffered so much damage in just a few years at the beginning of the new century when it comes to reported rates of trust in political institutions? This article maps the loss of political trust in the Netherlands and sets out to explain the developments that the statistics describe. A thought-provoking article that Bovens and Wille published in this journal names a number of temporary factors (fluctuations in the national economy and incumbent national governments) to explain the Dutch drop. This article points to the influence of more structural, systematic factors or underlying ‘currents’ that are concealed behind the factors that Bovens and Wille address: the persistence of consensus democracy on the one hand and the surge of the emotional culture and the risk society on the other. The accumulation and interaction of these three currents form the basis for the explication of the declining levels of trust in politics.Points for practitionersThis article maps the loss of political trust in the Netherlands at the beginning of the new millennieum, and sets out to explain this phenomenon. The analysis points to the influence of more structural and systematic factors — the persistence of consensus democracy on the one hand and the surge of the emotional culture and the risk society on the other — concealed behind the more temporal and transitory factors that Bovens and Wille have highlighted in an earlier issue of this journal. Restoring trust is contingent on the accumulation and interaction of these three currents.
Understanding the relationship between a national award scheme and performance
Authors: Radnor Zoe 
Published: October 2009

This article, drawing on a large data set collected as part of the national evaluation of a UK public service award scheme, aims to understand its relationship with performance measurement, reporting and management. The data set collected over three years includes case study analyses, two national surveys and a staff survey. Through a framework of performance measurement and management, the article illustrates how there is little direct connection made between the award scheme and performance measurement and management, although recognition is made that they do support each other in driving and supporting improvement and performance. The article highlights the complexities of the current improvement landscape for many public services but supports the finding that many of the organizations in the sample are taking a corporate approach to the engagement with improvement activities and initiatives in order to support performance. Points for practitioners This article illustrates that award schemes can support performance, maybe not always directly with performance measures but in recognizing good ideas and practice for service improvement. Applying for an award, disseminating good practice or taking time to understand awarded practice from another organization all appear to have a positive impact on performance. It is also important to take a corporate approach to improvement. For many public service organizations, the number of initiatives focused on performance, improvement and service delivery is vast, from award schemes to audit and inspection regimes. Organizations need to decide which, what and when to engage with in order to support focused improvement and performance.
Impact of administrative reform of the European Commission: results from a survey of heads of unit in policy-making directorates
Authors: Bauer Michael W. 
Published: October 2009

The Kinnock reform has changed the European Commission. This article discusses the link between reform effects and policy output. A survey of more than 100 heads of unit (HoU) of policy-making Directorates-General serves as the empirical basis. It is concluded that the recent reform of the Commission does indeed comprehensively redefine the role of the HoU. Their resource base to focus on policy drafting has been hugely reduced. Negative consequences for the organization’s potential to deliver policy draft of high quality are therefore very likely. Points for practitioners This article deals with the following areas: • Middle management as organizational backbone • The perils of decentralizing management functions • The impact of administrative reform on policy output.