bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of Novel Acyclic Nucleoside Analogues with anti‐Retroviral Activity.
Authors: Paju A. , Paeri M. , Selyutina A. , Zusinaite E. , Merits A. , Pehk T. , Siirde K. , Mueuerisepp A.‐M. , Kailas T. , Lopp M. 
Published: January 2011

AbstractNovel acyclic thymine nucleoside analogues (VI) are synthesized starting from enantiopure γ‐lactone acids (I).
ChemInform Abstract: Design, Synthesis, and Anticancer Activities of Novel Perfluoroalkyltriazole‐Appended 2′‐Deoxyuridines.
Authors: Park Sun Min , Yang Heeju , Park Song‐Kyu , Kim Hwan Mook , Kim Byeang Hyean 
Published: January 2011

AbstractA series of new perfluoroalkyltriazole‐appended 2‐deoxyuridines (V) (5 examples) is synthesized using the Sharpless click reaction.
ChemInform Abstract: Asymmetric Total Synthesis of Glycinoeclepin A (VIII): Generation of a Novel Bridgehead Anion Species.
Authors: Shiina Yasuhiro , Tomata Yoshihide , Miyashita Masaaki , Tanino Keiji 
Published: January 2011

AbstractThe preparation of the title compound, a hatchstimulating agent of the soybean cyst nematode, proceeds via construction of the CD‐segment (IV) and introduction of the A‐ ring moiety [cf.
ChemInform Abstract: First Total Synthesis of Ocimarin (III)
Authors: Yang Jin Hui , Li Yun Feng , Ji Cong Bin , Jiang Shi Zhi , Liu Wan Yi 
Published: January 2011

Abstractemploying a CeCl3‐catalyzed Pechmann condensation of resorcinol (II) and β‐keto ester (I) under solvent‐free conditions as key step
ChemInform Abstract: Unprecedented Triphosphinine Iron Interactions: Intramolecular Electron Transfer, Reactivity Round a Corner, and a Low‐Activated Ring Element Exchange Reaction
Authors: Eggers Karin , Heinemann Frank W. , Hennemann Matthias , Clark Timothy , Binger Paul , Zenneck Ulrich 
Published: January 2011

AbstractReview: 47 refs.
Preparation of Copper Chromite by Vaccum Freezing Drying Method and Its Catalytic Activity for Sulfuric Acid Decomposition
Authors: Su Tao , Zhang Ping , Wang Laijun , Chen Songzhe 
Published: January 2011

AbstractIodine sulfur (IS) process is one of the most promising routes for massive and CO2‐free hydrogen production. Among the three reactions IS process composed, decomposition of sulfuric acid is the most energy intensive step and has to be conducted in the presence of catalyst. In this work, copper chromite (CuCr2O4) was prepared, characterized, and used as the catalyst for sulfuric acid decomposition reaction. The co‐precipitation preparation method of CuCr2O4 which featured in vacuum freezing drying (VFD), was applied, and the main factors which influence the structure of CuCr2O4 such as pH values of the co‐precipitation solution and calcination temperature were investigated. Results showed that pH value affected the size of copper chromite granule, when pH was between 7 and 8, the size of prepared CuCr2O4 was in nanometer scale. Calcination temperature influenced the purity of the crystal. The samples were characterized by XRD, TEM and BET. The catalytic activity of CuCr2O4 prepared by VFD was evaluated and compared with CuCr2O4 prepared by usual co‐precipitation method and Pt/Al2O3. Results showed that the activity of CuCr2O4 was close to that of Pt catalyst, but apparently higher than that of CuCr2O4 prepared by usual method. In addition, it presents good stability in the 70 h test. Therefore, it was promising to be used in the sulfuric acid decomposition step of IS process.
Theoretical Studies on the Halogen Bond between Propargyl Radical and Dihalogen Molecules
Authors: Zeng Yanli , Li Xiaoyan , Zhang Xueying , Meng Lingpeng , Zheng Shijun 
Published: January 2011

AbstractMP2/aug‐cc‐pVDZ calculations are carried out on the geometries, vibrational frequencies, interaction energies and topological properties for the π‐type halogen‐bonded complexes between propargyl radical and dihalogen molecules ClF, BrF and BrCl. There are two kinds of geometries: complex (a) involves the interaction between the X (X=Cl, Br) atom and the midpoint of C(1) –C(2) bond, complex (b) involves the interaction between the X atom and C(3) atom. The lengths of the halogen bond, the frequencies of the halogen bond, the elongation extent of the X–Y (XY=ClF, BrF, BrCl) bond, topological parameters at the BCPs of the halogen bond and X–Y bond are all well consistent with the interaction energies. The interaction of complex (a) is stronger than that of complex (b); the interaction of propargyl···BrF is stronger than that of propargyl···ClF and propargyl···BrCl. For the complexes (a) and (b), the charge transfer is observed from propargyl radical to XY, the atomic energy, the dipolar polarization, and the volume of the halogen atom X decrease upon complex formation.
Multi‐spectroscopic Study on the Interaction between CdTe Quantum Dots and Bovine Serum Albumin
Authors: Fan Jingzhou , Zhou Juan , Sun Tingquan , Lü Shiyan , Tang Jinyan , Lü Jianquan 
Published: January 2011

AbstractThe interaction between CdTe quantum dots (QDs) and bovine serum albumin (BSA) was systematically investigated by fluorescence, UV‐vis absorption and circular dichroism (CD) spectroscopy under physiological conditions. The experimental results showed that the fluorescence of BSA could be quenched by CdTe QDs with a static quenching mechanism, indicating that CdTe QDs could react with BSA. The quenching constants according to the modified Stern‐Volmer equation were obtained as 1.710×106, 1.291×106 and 1.010×106 L·mol−1 at 298, 304, and 310 K, respectively. ΔH, ΔS and ΔG for CdTe QDs‐BSA system were calculated to be −33.68 kJ·mol−1, 6.254 J·mol−1·K−1 and −35.54 kJ·mol−1 (298 K), respectively, showing that electrostatic interaction in the system played a major role. According to F?rster theory, the distance between Trp‐214 in BSA and CdTe QDs was given as 2.18 nm. The UV‐vis, synchronous fluorescence and CD spectra confirmed further that the conformations of BSA after addition of CdTe QDs have been changed.
Theoretical Studies on Energetic Property and Stability of Pyrazine and Pyridine Derivatives
Authors: Fan Xiaowei , Gu Chenggang , Chen Gong , Ju Xuehai 
Published: January 2011

AbstractDensity functional calculations at the B3LYP level with 6‐311G** and aug‐cc‐pVDZ basis sets were performed to predict the heats of formation (HOFs) for two pyrazine derivatives and eight pyridine derivatives. In the isodesmic reactions designed for the computation of heats of formation (HOFs), pyrazine and pyridine were chosen as reference compounds. TheN‐oxidations for the ring nitrogen of pyrazine and pyridine derivatives decrease the HOF values whenN‐oxide oxygen is neighboring with amino groups, but increase when it neighbors with nitro groups. Thermal stability was evaluated via bond dissociation energies (BDE) at the UB3LYP/6‐311G** level. As a whole, the homolysis of C–NO2bonds is the main step for bond dissociation of the title compounds. The BDE values of title compounds are influenced by intramolecular hydrogen bonds. The hydrogen bond effects associated with the length of the H···O bonds were analyzed by the electron density at the critical points and natural bond orbital.
Highly Efficient InBr3 Catalyzed Michael Addition of Indoles to α,β‐Unsaturated Esters
Authors: Liu Ping , Chen Wei , Ren Kai , Wang Lei 
Published: January 2011

AbstractA highly efficient synthetic strategy toward Michael addition of indoles to α,β‐unsaturated esters has been developed using Lewis acid InBr3 as catalyst. The reactions generated 3‐substituted indoles in high yields with excellent regio‐selectivity in the presence of catalytic amount of InBr3 under mild reaction conditions. The method is simple, efficient and practical.
Synthesis and Anticancer Properties of Rare Earth Substituted Tungstophosphoric Polyoxometalate Containing 5‐Fluorouracil
Authors: Liu Xia , Wang Shuaishuai , Feng Changgen 
Published: January 2011

AbstractThree novel rare earth substituted polyoxometalates containing 5‐fluorouracil, K10C4H4FN2O2Pr(PW11O39)2·24H2O, K10C4H4FN2O2Nd(PW11O39)2·12H2O and K10C4H4FN2O2Sm(PW11O39)2·12.5H2O were synthesized and structurally characterized by elemental analysis, IR spectra, X‐ray powder diffraction and 183W NMR. The results indicate that the compounds have Keggin structure of heteropolyanion and ring structure of 5‐fluorouracil. The cytotoxicity test of the compounds in human renal embryonic cell HEK293 and the activity inhibiting human cervical carcinoma cell Hela were studied by the methyl thiazolyl tetrazolium method with 5‐fluorouracil for the positive control group. The toxicity of the compounds are lower than that of 5‐fluorouracil. K10C4H4FN2O2Pr(PW11O39)2·24H2O has no apparent toxicity in vitro and can inhibit Hela cells in vitro with significant difference compared with 5‐Fu.
Highly Efficient Palladacycle/Dihydroimidazolium Chloride System for the Suzuki‐Miyaura Cross‐Coupling of Aryl Halides (I, Br, Cl) with Arylboronic Acids
Authors: Wang Haiming , Wang Jinping , Qiu Wenwei , Yang Fan , Liu Xiaofeng , Tang Jie 
Published: January 2011

AbstractA combination of a tertiary amine‐based palladacycle and an N‐heterocyclic carbene ligand precursor (1, N,N‐bis‐mesityl‐4,5‐dihydroimidazolium chloride) has been applied to catalyze the Suzuki‐Miyaura cross‐coupling of aryl halides with arylboronic acids. The substrate scope is general: a variety of electron rich and deficient aryl halides (I, Br, Cl) and arylboronic acids were found to undergo the cross‐coupling reaction in good to excellent yields at low catalyst loading of 0.01–1 mol%.
Highly Efficient Oxidative Bromination of Alkanes with the HBr‐H2O2 System in the Presence of Catalyst
Authors: Li Yujin , Ju Jie , Jia Jianhong , Sheng Weijian , Han Liang , Gao Jianrong 
Published: January 2011

AbstractVarious cycloalkanes and straight‐chain alkanes were efficiently brominated with an aqueous HBr‐H2O2 system. This oxidative brominating process was promoted by catalysis and irradiation with light. The cycloalkanes were converted to the corresponding bromo‐cycloalkanes in moderate yields and the straight‐chain alkanes produced dominantly secondary bromides. This simple but effective bromination method of alkanes is characterized by high atom efficiency, inexpensive reagents and the absence of organic waste, which make it a good alternative to the existing method for CH activation through bromination.
Task Specific Onium Salt as Soluble Support in Multicomponent Synthesis of 4‐Aryl‐2‐amino‐3‐ethoxycarbonyl‐naphthopyrans
Authors: Lu Cuifen , Zhang Li , Yang Guichun , Chen Zuxing 
Published: January 2011

AbstractIn this paper was presented an application of task specific onium salt as soluble support in multicomponent synthesis of 2‐amino‐3‐ethoxycarbonyl‐naphthopyrans. The starting task‐specific onium salt was functionalized in good yield with chloroethyl alcohol, followed by three steps containing esterification, three components reaction and cleavage from onium salt to afford naphthopyrans in 60% –88% overall yields. All of the products were characterized by IR, 1H NMR, 13C NMR and MS techniques.
New Oenotheralanosterol A and B Constituents from the Oenothera biennis Roots
Authors: Ahmad Ateeque , Ali Mohd , Tandon Sudeep 
Published: January 2011

AbstractTwo new compounds oenotheralanosterol A and B along with four known compounds have been isolated from the roots of Oenothera biennis. Their structures have been elucidated with the help of 300 MHz NMR using 1D and 2D spectral methods viz: 1H and 13C NMR, 1H‐1H COSY, 1H‐13C HETCOR and DEPT aided by EIMS, ESI Mass and IR spectroscopy.
Selective Adsorption of Co(II) Ions by Whisker Surface Ion‐Imprinted Polymer: Equilibrium and Kinetics Modeling
Authors: Pan Jianming , Guan Wei , Zhang Zulei , Wang Xue , Li Chunxiang , Yan Yongsheng 
Published: January 2011

AbstractBased on sodium trititanate whisker as support particles, the surface ion‐imprinted polymer (S‐IIP) was synthesized for the selective adsorption of Co(II) ions from aqueous solution. Characterization of S‐IIP was achieved by FTIR spectra and SEM micrographs. Kinetic properties were successfully investigated by the pseudo‐first‐order model and pseudo‐second‐order model, and a chemisorption process as the essential adsorption step was also proposed. Equilibrium data were fitted with the Langmuir, Dubinin‐Radushkevich and Freundlich isotherm equations, and the maximum adsorption amount of monolayer saturation for S‐IIP was 33.75 mg/g at 298 K. Moreover, dimensionless separation factor RL (RL<1.0) indicated a highly favourable adsorption system between Co(II) ions and S‐IIP. Selectivity experiments showed that selective adsorption of Co(II) ions for S‐IIP was significantly higher than that of non‐imprinted polymer (NIP).
Glucose Biosensor Based on the Fabrication of Glucose Oxidase in the Bio‐Inspired Polydopamine‐Gold Nanoparticle Composite Film
Authors: Wei Yinyin , Zhang Ningdan , Li Ying , Shi Guoyue , Jin Litong 
Published: January 2011

AbstractA highly efficient enzyme immobilization method has been developed for electrochemical biosensors using polydopamine films with gold nanoparticles (AuNPs) embedded. This simple enzyme fabrication method can be performed in very mild conditions and stored in a long time with high bioactivity. The fabricated amperometric glucose biosensor exhibited a high and reproducible sensitivity, wide linear dynamic range and low limit of detection (LOD) (0.1 μmol·L−1). A low value of 1.5 mmol·L−1 for the apparent Michaelis‐Menten constant KappM was obtained. The high sensitivity, wide linear range, good reproducibility and stability make this biosensor a promising candidate for portable amperometric glucose biosensor.
CuO Crystalline Modified Glassy Carbon Electrodes for Anodic Amperometric Determination of Hydrogen Peroxide
Authors: Lin Xiangqin , Jing Zhenhui 
Published: January 2011

AbstractAs an alternative selection of electrocatalytic surface modifier, the electrochemically generated copper oxides is re‐ investigated by using cyclic voltammetry (CV), scanning electron microscopy (SEM) and X‐ray photoelectron spectroscopy (XPS). Interesting phenomena have been found, which indicate that the electrodeposition from the Cu2+ solution under cyclic voltammetric conditions can generate a transparent Cu(OH)2 crystalline on the surface of glassy carbon electrodes, and this crystalline can be further transferred to a novel cubic opaque CuO crystalline of about 300 nm in size by second step of cyclic voltammetry in pH 12 NaOH solution. The final electrode (denoted as nano‐CuO/GCE) can catalyze the oxidation (as well as the reduction) of H2O2 in basic solutions. It shows pH dependent three‐part catalytic mechanism in the range from pH 7 to pH 14. In 0.10 mol/L NaOH solution, the amperometric response at 0.15 V (vs. SCE) can give a current sensitivity as high as 139 mA/(mol·L−1) in the rage of 5.0×10−7−6.0×10−4 mol/L with a lower detection limit (s/n=3) of 2.5×10−8 mol/L, and a current sensitivity of 78.4 mA/(mol·L−1) in the rage of 6.0×10−4–2.0×10−3 mol/L. This electrode also has excellent reproducibility and stability. The mechanisms for the two steps of preparation and the catalytic reactions are proposed. The nano‐CuO crystalline modified electrode may have more applications in the field of electrochemical sensing.
A Hydrogen Peroxide Biosensor Based on Room Temperature Ionic Liquid Functionalized Graphene Modified Carbon Ceramic Electrode
Authors: He Yaping , Zheng Jianbin , Li Kuangtian , Sheng Qinglin , Qiao Ningqiang 
Published: January 2011

AbstractA room temperature ionic liquid (IL) 1‐butyl‐3‐methylimidazolium hexafluorophosphate functionalized graphene (GE) was prepared and a hydrogen peroxide (H2O2) biosensor was fabricated by immobilizing hemoglobin (Hb) into the IL‐GE composite film. UV‐visible and Fourier transform infrared spectra of the composite film indicated that Hb retained its native structure in the film. Electrochemical investigation of the biosensor showed a pair of well‐defined, quasi‐reversible redox peaks with Epa=−0.209 V and Epc= −0.302 V (vs. SCE) in pH 7.0 phosphate buffer solution at the scan rate of 100 mV/s. To the reduction of H2O2, the biosensor had a good linear range from 8.0×10−7 to 1.8×10−4 mol/L with a detection limit of 3.0×10−7 mol/L. The apparent Michaelis‐Menten constant KappM was estimated to be 3.4×10−5 mol/L.
Poly(methyl methacrylate)/Methacryl‐POSS Nanocomposites with Excellent Thermal Properties
Authors: Qin Yuancheng , Bi Yutie , Ren Hongbo , Zhu Fanghua , Luo Meiming , Zhang Lin 
Published: January 2011

AbstractPoly(methyl methacrylate) (PMMA) nanocomposites containing (methacryloxy)propyl polyhedral oligomeric silsesquioxane (methacryl‐POSS) were prepared by bulk‐polymerization process. The structures of the products were characterized by FTIR, solid‐state NMR, TEM, XRD, DSC, TGA, XPS and UV‐Vis spectra. The hybrid materials were found to be largely homogeneous. DSC and TGA results indicate that the thermal properties of PMMA nanocomposites are significantly improved. The glass transition temperature (Tg) and thermal decomposition temperature (Tdec) of the nanocomposites increased by 58 and 110°C, respectively. The bulk hybrid material maintains excellent optical transparency in visible region.
Color Removal from Synthetic Textile Wastewater by Sono‐Fenton Process
Authors: Özdemir Celalettin , Öden Muhammed Kamil , Şahinkaya Serkan , Kalipçi Erkan 
Published: January 2011

AbstractIn this study, the oxidative decolorization of C.I. reactive yellow 145 (RY 145) from synthetic textile wastewater including RY 145 and polyvinyl alcohol by Fenton and sono‐Fenton processes which are the combination of Fenton process with ultrasound has been carried out. The effects of some operating parameters which are the initial pH of the solution, the initial concentration of Fe2+, H2O2, and the dye, temperature, and agitation speed on the color and chemical oxygen demand (COD) removals have been investigated. The optimum conditions have been found as [Fe2+] = 20 mg/L, [H2O2] = 20 mg/L, pH 3 for Fenton process and [Fe2+] = 20 mg/L, [H2O2] = 15 mg/L, pH 3 for sono‐Fenton process by indirectly sonication at 35 kHz ultrasonic frequency and 80 W ultrasonic power. The color and COD removal efficiencies have been obtained as 91 and 47% by Fenton process, and 95 and 51% by sono‐Fenton processes, respectively. Kinetic studies have been performed for the decolorization of RY 145 under optimum conditions at room temperature. It has been determined that the decolorization has occurred rapidly by sono‐Fenton process, compared to Fenton process.
Design and Synthesis of Novel Cyclooxygenase‐1 Inhibitors as Analgesics: 5‐Amino‐2‐ethoxy‐N‐(substituted‐phenyl)benzamides
Authors: Fukai Ryosuke , Zheng Xiaoxia , Motoshima Kazunori , Tai Akihiro , Yazama Futoshi , Kakuta Hiroki 
Published: January 2011

AbstractWe previously found that N‐(4‐aminophenyl)‐4‐trifluoromethylbenzamide (TFAP), a COX‐1 inhibitor, exhibits an analgesic effect without causing gastric damage. Unfortunately, TFAP causes reddish purple coloration of urine, and its analgesic effect is less potent than that of indomethacin. Herein we describe our study focusing on the development of 4‐ and 5‐amino‐2‐alkoxy‐N‐phenylbenzamide scaffolds, designed on the basis of the structures of TFAP and parsalmide, another known COX‐1 inhibitory analgesic agent. 5‐Amino‐2‐ethoxy‐N‐(2‐ or 3‐substituted phenyl)benzamide derivatives exhibited analgesic activity in a murine acetic acid induced writhing test. Among these compounds, 5‐amino‐2‐ethoxy‐N‐(2‐methoxyphenyl)benzamide (9 v) possesses potent COX‐1 inhibitory and analgesic activities, similar to those of indomethacin. In addition, 5‐amino‐2‐ethoxy‐N‐(3‐trifluoromethylphenyl)benzamide (9 g) showed a more potent analgesic effect than indomethacin or 9 v without causing apparent gastric damage or coloration of urine, although its COX‐1 inhibitory activity was weaker than that of indomethacin or 9 v. Thus, 9 g and 9 v appear to be promising candidates for analgesic agents and are attractive lead compounds for further development of COX‐1 inhibitors.
Staff construal of inpatients with anorexia nervosa
Authors: Woodrow Ceri , Fox John R. E. , Hare Dougal Julian 
Published: January 2011

AbstractThe present study uses personal construct theory and the repertory grid technique to examine staff views of individual clients with a diagnosis of anorexia nervosa, in particular those clients who purge and restrict. Fourteen members of nursing staff, both qualified and non‐qualified, participated in the research. The results suggest that the 14 members of staff interviewed did construe clients who purge and clients who restrict in markedly different ways. The theoretical implications of this finding are discussed. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Clients with anorexia who purge and those who restrict may present with different needs.• The care package may therefore need to be altered.• The study supports a differentiation between Anorexia Nervosa subtypes.
Electric Charging in Dielectric Barrier Discharges with Asymmetric Gamma‐Coefficients
Authors: Stollenwerk L. , Stroth U. 
Published: January 2011

AbstractA dielectric barrier discharge with different electrode surfaces is investigated and the dynamic evolution of surface charge on the dielectric surface is measured optically. It is found that the amount of surface charge after the positive and the negative half‐cycle are not equal, i.e. a bias charge emerges. To understand this phenomenon, the transfered charge per half‐cycle is estimated from the Paschen curve and the shape of the driving voltage waveform. It turns out that the charge bias is necessary to compensate for the asymmetry of the discharge conditions due to the different surfaces and hence is required for a balanced charge transfer in the steady state (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
The Quantum Equation of State of Fully Ionized Plasmas
Authors: Hussein N. A. , Ibrahim D. A. E. 
Published: January 2011

AbstractThe quantum equation of state of the electron‐ion‐plasmas in thermal equilibrium is derived; the pressure until the third virial coefficient is calculated. We consider only the thermal equilibrium plasma in the case of nλ3ab ≪ 1 where λ2ab = ((ħ2)/(mabKT)) is the thermal De Broglie wavelength. The formulas contain the contributions of the exchange effects. Our equation of state is compared with result of Ebeling et al. who calculated the pressure until the second virial coefficient only and in the case of χλee ≪ 1 where χ is the Debye length. Upon comparison with Ebeling et al. one observes that the considerable contribution of the third virial coefficient in the region of high temperatures (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
SPICE: Exploration and analysis of post‐cytometric complex multivariate datasets
Authors: Roederer Mario , Nozzi Joshua L. , Nason Martha C. 
Published: January 2011

AbstractPolychromatic flow cytometry results in complex, multivariate datasets. To date, tools for the aggregate analysis of these datasets across multiple specimens grouped by different categorical variables, such as demographic information, have not been optimized. Often, the exploration of such datasets is accomplished by visualization of patterns with pie charts or bar charts, without easy access to statistical comparisons of measurements that comprise multiple components. Here we report on algorithms and a graphical interface we developed for these purposes. In particular, we discuss thresholding necessary for accurate representation of data in pie charts, the implications for display and comparison of normalized versus unnormalized data, and the effects of averaging when samples with significant background noise are present. Finally, we define a statistic for the nonparametric comparison of complex distributions to test for difference between groups of samples based on multi‐component measurements. While originally developed to support the analysis of T cell functional profiles, these techniques are amenable to a broad range of datatypes. Published 2011 Wiley‐Liss, Inc.