bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospective study of erythropoietin use on quality of life and cost effectiveness in acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation patients
Authors: Michallet Mauricette , Goldet Karine , Sobh Mohamad , Morisset Stéphane , Chelghoum Youcef , Thomas Xavier , Barraco Fiorenza , Ducastelle Sophie , Labussière Hélène , Renzullo Catherine , Paillet Carole , Pivot Christine , Straaten Perrine Badol‐Van , Denis Angelique , Termoz Anne , Detrait Marie , Nicolini Franck‐Emmanuel , Jaisson‐Hot Isabelle 
Published: June 2012

AbstractBACKGROUND:Despite frequent anemia and multiple transfusions in patients undergoing chemotherapy and allogeneic hematopoietic stem cell transplantation (allo‐HSCT) for acute myeloid leukemia , recommendations for use of erythropoiesis‐stimulating agents (ESAs) in these populations are still missing. The primary objective was the effect of ESA administration on patient's quality of life (QoL). Secondary objectives were hemoglobin (Hb) recovery, red blood cell (RBC) transfusions, overall survival, and event‐free survival.METHODS:Adult patients with Hb ≤ 11 g/dL after consolidation chemotherapy for acute myeloid leukemia (group 1), or after allo‐HSCT for any hematological diseases (group 2), were prospectively included. ESA was administered subcutaneously once per week during a maximum period of 6 months and was stopped when Hb level reached 12 g/dL. A paired‐matched analysis using a historical control group was performed for secondary endpoints. Fifty‐two patients were included in group 1, and 55 patients were in group 2.RESULTS:For the global population, a significant improvement of QoL was noticed with ESA use; 83% (group 1) and 71% (group 2) of patients achieved an Hb level ≥ 12 g/dL without transfusion requirement. The pair‐matched analysis showed a reduction of 4 RBC units per patient in group 1 (P = .0002) and 3 RBC units per patient in group 2 (P = .04). No significant difference in terms of thromboembolic events, overall survival, and event‐free survival was observed between ESA and control groups. A RBC transfusion median savings of €1712 per patient was estimated in each group.CONCLUSIONS:ESAs have a clinical and economic benefit on Hb recovery, could improve a patient's QoL, and lead to a significant reduction in number of RBC transfusions with no effect on survival. Cancer 2013. © 2012 American Cancer Society.
A dynamic channel assignment strategy based on cross‐layer design for wireless mesh networks
Authors: Sun Weifeng , Fu Tong , Xia Feng , Qin Zhenquan , Cong Rong 
Published: June 2012

SUMMARYIn wireless mesh networks (WMNs), if nonoverlapped channels or partially overlapped channels are used properly, the throughput can be improved drastically. However, the number of nonoverlapped channels is limited in wireless communication standards. An effective channel assignment algorithm for a WMN is necessary to increase the utilization rate of space and nonoverlapped channels. Static channel assignment algorithms can improve network throughput, but their accuracies are not satisfactory in common scenarios. Dynamic channel assignment algorithms can allocate channels according to the status of adjacent links in WMNs. A dynamic channel assignment algorithm needs cross‐layer design to get the information of routing. A routing‐information‐aware channel assignment algorithm based on a cross‐layer design is proposed, which is named R‐CA. The proposed method can dynamically allocate channels for wireless nodes when they need communication and release channels after data transmission. In R‐CA, limited channel resources can be used efficiently by more wireless nodes, and hence the communication throughput can be improved. Simulation results show that our channel allocation strategy can effectively ensure and enhance the network throughput and packet delivery rate in WMNs. Copyright © 2012 John Wiley & Sons, Ltd.
Retraction statement: Racist biases in legal decisions are reduced by a justice focus
Authors: Lammers Joris , Stapel Diederik A. 
Published: June 2012

The following article from European Journal of Social Psychology, “Racist biases in legal decisions are reduced by a justice focus” by Joris Lammers and Diederik A. Stapel published online on 1 December 2010 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the co‐author, the journal Editor in Chief, Tom Postmes, and John Wiley and Sons Ltd. The retraction has been agreed following the results of an investigation into the work of Diederik A. Stapel (https://www.commissielevelt.nl/). The Levelt Committee has determined that this article contained data that was fabricated as supplied by Diederik A. Stapel. His co‐author was unaware of his actions, and not in any way involved.REFERENCELammers, J. & Stapel, D. A. (2011). Racist biases in legal decisions are reduced by a justice focus. European Journal of Social Psycholology, 41, 375–387. DOI:10.1002/ejsp.783
Retraction statement: Judging the unexpected: Disconfirmation of situation‐specific expectancies
Authors: Noordewier Marret K. , Stapel Diederik A. 
Published: June 2012

The following article from European Journal of Social Psychology, “Judging the unexpected: Disconfirmation of situation‐specific expectancies” by Marret K. Noordewier and Diederik A. Stapel published online on 1 January 2009 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the co‐author, the journal Editor in Chief, Tom Postmes, and John Wiley and Sons Ltd. The retraction has been agreed following the results of an investigation into the work of Diederik A. Stapel (https://www.commissielevelt.nl/). The Levelt Committee has determined that this article contained data that was fabricated as supplied by Diederik A. Stapel. His co‐author was unaware of his actions, and not in any way involved.REFERENCENoordewier, M. K. & Stapel, D. A. (2009). Judging the unexpected: Disconfirmation of situation‐specific expectancies. European Journal of Social Psychology, 39, 944–956. DOI:10.1002/ejsp.591
Retraction statement: When nothing compares to me: how defensive motivations and similarity shape social comparison effects
Authors: Stapel Diederik A. , Johnson Camille S. 
Published: June 2012

The following article from European Journal of Social Psychology, “When nothing compares to me: How defensive motivations and similarity shape social comparison effects” by Diederik A. Stapel and Camille S. Johnson, published online on 26 September 2006 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the co‐author, the journal Editor in Chief, Tom Postmes, and John Wiley and Sons Ltd. The retraction has been agreed following the results of an investigation into the work of Diederik A. Stapel (https://www.commissielevelt.nl/). The Levelt Committee has determined that this article contained data that was fabricated by Diederik A. Stapel. His co‐author was unaware of his actions, and not in any way involved.REFERENCEStapel, D. A. &; Johnson, C. S. (2007). When nothing compares to me: how defensive motivations and similarity shape social comparison effects. European Journal of Social Psychology, 37, 824–838. DOI:10.1002/ejsp.390
Gene expression changes in initiation and progression of oral squamous cell carcinomas revealed by laser microdissection and oligonucleotide microarray analysis
Authors: Sumino Jun , Uzawa Narikazu , Okada Norihiko , Miyaguchi Ken , Mogushi Kaoru , Takahashi Ken‐Ichiro , Sato Hiroaki , Michikawa Chieko , Nakata Yoshimi , Tanaka Hiroshi , Amagasa Teruo 
Published: June 2012

AbstractOral carcinogenesis is a complex process involving multiple genes. However, the genetic changes involved in this process are not apparent in identical oral squamous cell carcinomas (OSCCs). According to pathological characteristics, samples of normal tissue, oral dysplastic lesions (ODLs), and invasive cancers were obtained from identical OSCCs using laser microdissection (LMD). Large‐scale gene expression profiling was carried out on 33 samples derived from 11 OSCCs. We analyzed genes differentially expressed in normal tissues vs. ODLs and in ODLs vs. invasive tumors and identified 15 candidate genes with continuously increasing or decreasing expression during oral carcinogenesis. One of these genes, ISG15, was chosen for further characterization. Real‐time quantitative reverse transcription‐polymerase chain reaction and immunohistochemical analysis confirmed that ISG15 expression consistently increased during oral tumorigenesis. An ISG15 high‐expression level was significantly associated with poor prognosis (p = 0.027). In addition, patients with high‐expression tumors had a poorer 5‐year survival rate than patients with low expression levels (p = 0.019). In conclusion, we identified 15 genes with continuously increasing or decreasing expression during oral carcinogenesis. One of these, ISG15, is likely to be associated with both dysgenesis and tumorigenesis and may be a potential prognostic marker for oral cancer.
Quantitative short echo time 1H MRSI of the peripheral edematous region of human brain tumors in the differentiation between glioblastoma, metastasis, and meningioma
Authors: Wijnen J.P. , Idema A.J.S. , Stawicki M. , Lagemaat M.W. , Wesseling P. , Wright A.J. , Scheenen T.W.J. , Heerschap A. 
Published: June 2012

AbstractPurpose:To assess metabolite levels in peritumoral edematous (PO) and surrounding apparently normal (SAN) brain regions of glioblastoma, metastasis, and meningioma in humans with 1H‐MRSI to find biomarkers that can discriminate between tumors and characterize infiltrative tumor growth.Materials and Methods:Magnetic resonance (MR) spectra (semi‐LASER MRSI, 30 msec echo time, 3T) were selected from regions of interest (ROIs) under MRI guidance, and after quality control of MR spectra. Statistical testing between patient groups was performed for mean metabolite ratios of an entire ROI and for the highest value within that ROI.Results:The highest ratios of the level of choline compounds and the sum of myo‐inositol and glycine over N‐acetylaspartate and creatine compounds were significantly increased in PO regions of glioblastoma versus that of metastasis and meningioma. In the SAN region of glioblastoma some of these ratios were increased. Differences were less prominent for metabolite levels averaged over entire ROIs.Conclusion:Specific metabolite ratios in PO and SAN regions can be used to discriminate glioblastoma from metastasis and meningioma. An analysis of these ratios averaged over entire ROIs and those with most abnormal values indicates that infiltrative tumor growth in glioblastoma is inhomogeneous and extends into the SAN region. J. Magn. Reson. Imaging 2012;36:1072–1082. © 2012 Wiley Periodicals, Inc.
The effect of co‐composted cabbage and ground phosphate rock on the early growth and P uptake of oilseed rape and perennial ryegrass
Authors: Walker Robin L. , Edwards Anthony C. , Maskell Phillip , Watson Christine A. , Rees Robert M. , Knox Oliver G.G. , Stockdale Elizabeth A. 
Published: June 2012

AbstractPhosphorus (P) availability to crops in organic systems can be a major issue, with the use of readily available forms often restricted. One product that can be used in organically managed systems, that is also relatively easily accessible to growers, is phosphate rock, although its solubility and therefore crop availability is often poor. One possible approach to improve this situation is co‐composting phosphate rock with selected organic waste materials. Various ratios of phosphate rock and cabbage (Brassica oleracea L.) residues were co‐composted and the products tested at different rates of application. The effects were assessed over 12 weeks using oilseed rape (Brassica napus L.) and perennial ryegrass (Lolium perenne L.) as bioassay crops in a pot experiment. At harvest, estimates of P derived from cabbage and phosphate rock for the lowest of two rates of compost were ≈ 2 and 10 mg P pot–1 for oilseed rape, compared to 5 and 2 mg P pot–1 for perennial ryegrass, respectively. Roots tended to have higher P concentrations than shoots. The crops showed differences in their abilities to access various P sources, with oilseed rape effectively taking P from phosphate rock, whereas perennial ryegrass was more effective at accessing cabbage‐derived P (the main substrate in the compost). Oilseed rape was able to take up 20% of the total P applied as phosphate rock, whereas perennial ryegrass took up less than 5% of the total P applied from this material. Both pre‐ and post‐application solubilisation/transformation mechanisms were involved in supplying plant‐available P. Quantifying the relative contribution from individual P sources remains problematic even within this relatively simple system.
Effect of source–sink manipulation on accumulation of micronutrients and protein in wheat grains
Authors: Zhang Yinghua , Zhang Yongping , Liu Na , Su Da , Xue Qingwu , Stewart Bob A. , Wang Zhimin 
Published: June 2012

AbstractThe effect of source and sink manipulation on accumulation of micronutrients (Fe, Zn, Mn, Cu) and protein in wheat grains was studied in a field experiment and ear culture. The source and sink manipulation was obtained by reducing assimilate source (through defoliation and spike shading) or sink (through 50% spikelets removal) after anthesis in the field and by changing sucrose or NH4NO3 levels of the culture media in ear culture. In the field experiment, reducing source and sink generally increased Fe, Zn, Mn, Cu, and protein concentrations except defoliation which decreased Mn concentration. Grain yield as well as micronutrient and protein contents in grains were all reduced by reducing source and sink sizes, suggesting that the accumulation of micronutrients and protein in grains was restricted by source supply and sink capacity. In ear culture, the supply of 20 to 80 g L–1 sucrose increased grain weight and yield, but decreased grain Fe, Zn, Mn, Cu, and protein concentrations. The supply of 0.57 to 2.28 g L–1 NH4NO3 increased grain yield and the concentrations and contents of micronutrients and protein. All these results show that micronutrient and protein accumulation in grains can be affected by the source–sink relationship of carbohydrate and nitrogen. Adequate N supply can simultaneously increase grain yield and the accumulation of Fe, Zn, Mn, Cu, and protein.
An electronic micropenetrometer (EMP) for field measurements of biological soil crust stability
Authors: Laureen Drahorad Sylvie , Felix‐Henningsen Peter 
Published: June 2012

AbstractDespite the importance of biological soil crusts (BSC) for ecosystem functions in arid and semiarid areas, little information on their mechanical stability is available. Goal of this study was to develop a micropenetrometer (EMP) that allows to determine BSC stability at high spatial resolutions. First results show that differences in BSC stability at 39 μm resolution can be detected and that cyanobacterial BSC has an average penetration resistance of 0.75 MPa.
Random‐access distributed fiber sensing
Authors: Zadok A. , Antman Y. , Primerov N. , Denisov A. , Sancho J. , Thevenaz L. 
Published: June 2012

AbstractOptical sensing offers an attractive solution to the societal concern for prevention of natural and human‐generated threats and for efficient use of natural resources. The unprecedented properties of optical fibers make them ideal for implementing a ‘nervous system’ in structural health monitoring: they are small, low‐cost and electrically and chemically inert. In particular, the nonlinear interaction of stimulated Brillouin scattering allows for the distributed measurement of strain and temperature with tens of km range. In this work, a novel, radar‐inspired technique for random‐access Brillouin scattering‐based sensors is shown, making a significant step towards a real optical sensing nerve. The method selectively addresses each fiber segment as a distinct sensing element in a synaptic neuronal system. The measurement principle relies on phase‐coding of both the Brillouin pump and signal waves by a high‐rate, pseudo‐random bit sequence. Temperature measurements with 1 cm resolution are reported. The measurement range is scalable to several km.
Dual‐wavelength optical parametric oscillator using antiresonant ring interferometer
Authors: Esteban‐Martin A. , Ramaiah‐Badarla V. , Ebrahim‐Zadeh M. 
Published: June 2012

AbstractA novel technique for coupling of two resonant optical cavities using an antiresonant ring (ARR) interferometer is reported. By deploying two synchronously‐pumped femtosecond optical parametric oscillators (OPOs), it is shown that the use of an ARR can provide an intracavity common path for the two oscillating fields, but without gain coupling between the two nonlinear media. The new technique permits the generation of two signal (idler) wavelengths, which can be independently and arbitrarily varied across the OPO tuning range. The absence of gain coupling also enables unrestricted and uninterrupted tuning through wavelength degeneracy at any arbitrary point within the OPO tuning range. It is shown that signal wavelength pairs tunable across 1500–1580 nm, corresponding to a frequency separation from ∼ 10 THz down to exact degeneracy, can be generated from the coupled OPOs, limited only by the reflectivity of the available mirrors.
A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial
Authors: Lynch David R. , Willi Steven M. , Wilson Robert B. , Cotticelli M. Grazia , Brigatti Karlla W. , Deutsch Eric C. , Kucheruk Olena , Shrader William , Rioux Patrice , Miller Guy , Hawi Amale , Sciascia Thomas 
Published: June 2012

AbstractThis study tested the ability of A0001 (α‐tocopheryl quinone; EPI‐A0001), a potent antioxidant, to improve in vitro measures, glucose metabolism, and neurological function in Friedreich ataxia. We used an in vitro study of protection from cell toxicity followed by a double‐blind, randomized, placebo‐controlled trial of 2 doses of A0001 in 31 adults with Friedreich ataxia. The primary clinical trial outcome was the Disposition Index, a measure of diabetic tendency, from a frequently sampled intravenous glucose tolerance test, evaluated 4 weeks into therapy. Secondary neurologic measures included the Friedreich Ataxia Rating Scale. A0001 potently inhibited cell death in Friedreich ataxia models in vitro. For the clinical trial, mean guanine‐adenine‐adenine repeat length was 699, and mean age was 31 years. Four weeks after treatment initiation, differences in changes in the Disposition Index between subjects treated with A0001 and placebo were not statistically significant. In contrast, a dose‐dependent improvement in the Friedreich Ataxia Rating Scale score was observed. Patients on placebo improved 2.0 rating scale points, whereas patients on low‐dose A0001 improved by 4.9 points (P = .04) and patients on a high dose improved by 6.1 points (P < .01). Although A0001 did not alter the Disposition Index, it caused a dose‐dependent improvement in neurologic function, as measured by the Friedreich Ataxia Rating Scale. Longer studies will assess the reproducibility and persistence of neurologic benefit. © 2012 Movement Disorder Society
An anisotropic damage–plasticity model for saturated quasi‐brittle materials
Authors: Hu D. W. , Zhou H. , Shao J. F. 
Published: June 2012

SUMMARYThis article is devoted to numerical modeling of anisotropic damage and plasticity in saturated quasi‐brittle materials such as rocks and concrete. The damaged materials are represented by an isotropic poroelastic matrix containing a number of families of microcracks. Based on previous works, a discrete thermodynamic approach is proposed. Each family of microcracks exhibits frictional sliding along crack surfaces as well as crack propagation. The frictional sliding is described by a Coulomb–Mohr‐type plastic criterion by taking into account the effect of fluid pressure through a generalized effective stress concept. The damage evolution is entirely controlled by and coupled with the frictional sliding. The effective elastic properties as well as Biot's coefficients of cracked porous materials are determined as functions of induced damage. The inelastic deformation due to frictional sliding is also taken into account. The procedure for the identification of the model's parameters is presented. The proposed model is finally applied to study both mechanical and poromechanical responses of a typical porous brittle rock in drained and undrained compression tests as well as in interstitial pressure controlled tests. The main features of material behaviors are well reproduced by the model. Copyright © 2012 John Wiley & Sons, Ltd.
Does pre‐entry licensing undermine the performance of subsequent independent activities? Evidence from the global aerospace industry, 1944–2000
Authors: Mulotte Louis , Dussauge Pierre , Mitchell Will 
Published: June 2012

AbstractWe study how firms' use of in‐licensing for their initial entry to a business domain can detract from the performance of their subsequent autonomous endeavors in the domain. We argue that in‐licensing produces high levels of causal ambiguity about factors that drive the performance achieved with the licensed product. In turn, the experience that firms gather through pre‐entry licensing is likely to generate superstitious learning and overconfidence that undermine the performance of licensees' subsequent independent operations. The biases will be particularly strong in the face of contextual dissimilarity. We find consistent evidence in a study of firms that entered the global aircraft industry between 1944 and 2000. The research helps advance the understanding of the benefits and costs of markets for technology. Copyright © 2012 John Wiley & Sons, Ltd.
Layered reasoning for randomized distributed algorithms
Authors: Swaminathan Mani , Katoen Joost-Pieter , Olderog Ernst-Rüdiger 
Published: June 2012

Abstract
This paper adopts the communication closed layer (CCL) concept of Elrad and Francez to the formal reasoning of randomized distributed algorithms. We do so by enriching probabilistic automata (PA) with a layered composition operator, an intermediate between parallel and sequential composition. Layered composition is used to establish probabilistic counterparts of the CCL laws that exploit independence and/or precedence conditions between the constituent PA. The probabilistic CCL laws enable partial order (po-) equivalence when layered composition is replaced by sequential composition. Such po-equivalence induces a purely syntactic partial-order state space reduction via layered separation in compositions of PA while preserving probabilistic next-free linear-time properties. The feasibility of such layered separation is demonstrated on a randomized mutual exclusion algorithm by Kushilevitz and Rabin, complementing an algebraic approach (for analyzing this algorithm) by McIver, Gonzalia, Cohen, and Morgan.