bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness after immunization with BNT162b2 and Gam-COVID-Vac for SARS-CoV-2 and neutralizing antibody titers in health care workers
Authors: Emin Melda , Cibrev Dragan , Kerala Coskun , Petrovska-Cvetkovska Dragana , Ajeti Valdrina , Ampova Hristina , Kostovska Irena , Tosheska-Trajkovska Katerina 
Published: May 2024

Abstract

Objectives
The aim of this study was to describe the effectiveness of the vaccines (Tozinameran and Sputnik V), administered on a convenience sample of healthcare workers, and also to describe the relationship between the levels of neutralizing antibodies (NAbs) and the type of vaccine used, as well as their association with incident cases during follow-up.

Methods
The study included 262 participants, who underwent vaccination during the period from September 2021 until August 2022. For determining the levels of NAbs we used the CLIA based method, and all the samples were processed with the SNIBE Maglumi 800 analyzer. The patients were observed for one year for occurrence of incident infection.

Results
The participants with prior SARS-CoV-2 positivity showed substantially higher titer of NAbs (8.86 vs. 0.94, p<0.001). The participants in the Gam-COVID-Vac group had median levels of NAbs of 1.57 (IQR 0.42–5.73), while they in the Tozinameran group showed substantially higher levels of 2.37 (IQR 0.9–6.27). The incident cases after immunization had substantially lower median values of NAbs when compared to the rest (0.48 vs. 3.97, p<0.001), and the interval between the second dose and the serological measurements were similar.

Conclusions
The current study showed that the tested vaccines demonstrated vaccine effectiveness of over 50 % during the first year after the vaccination in a sample of health care workers. Although health care workers remain separate population group, when compared to the rest, the results could be extrapolated to populations with similar age and immune experience.
Load-Velocity Profiles Before and After Heated Resistance Exercise
Authors: Sweet Daniel K. , Qiao JianBo , Rosbrook Paul , Pryor J. Luke 
Published: May 2024

Abstract
Sweet, DK, Qiao, J, Rosbrook, P, and Pryor, JL. Load-velocity profiles before and after heated resistance exercise. J Strength Cond Res 38(6): 1019–1024, 2024—This study examined neuromuscular performance using load-velocity (L-V) profiles in men and women before and after resistance exercise (RE) in hot (HOT; 40° C) and temperate (TEMP; 21° C) environments. Sixteen (f = 8, m = 8) resistance-trained individuals completed a single 70-minute whole-body high-volume load (6 exercises, 4 sets of 10 repetitions) RE bout in HOT and TEMP. Before and after RE, rectal temperature (TRE), muscle temperature of the vastus lateralis (TVL) and triceps brachii (TTB), and an L-V profile for the deadlift and bench press were recorded. Thermoregulatory and L-V data were analyzed using separate 2-way repeated measures analysis of variances (ANOVAs; condition [hot, temperate] and time [pre, post]) with significance level set at p ≤ 0.05. Deadlift peak velocity was reduced at 60% 1 repetition maximum (1RM) after RE in HOT but not TEMP. Peak velocity of 40% 1RM bench press was lower in TEMP vs. HOT pre-RE (p < 0.01). Peak velocity was decreased at all loads in the deadlift L-V profile after RE, regardless of condition. Despite elevated TRE (TEMP; 37.58 ± 0.35, HOT; 38.20 ± 0.39° C), TVL (TEMP; 35.24 ± 0.62, HOT; 37.92 ± 0.55° C), and TTB (TEMP; 35.05 ± 0.78, HOT; 38.00 ± 0.16° C) after RE in HOT vs. TEMP (p < 0.01), RE in HOT did not broadly affect L-V profiles. This indicates heated resistance exercise can be performed with high-volume load and high ambient temperature with minimal performance impairment.
Validity of the Hawkin Dynamics Wireless Dual Force Platform System Against a Piezoelectric Laboratory Grade System for Vertical Countermovement Jump Variables
Authors: Dos'Santos Thomas , Evans Daniel T. , Read Dale B. 
Published: May 2024

Abstract
Dos'Santos, T, Evans, DT, and Read, DB. Validity of the Hawkin dynamics wireless dual force platform system against a piezoelectric laboratory grade system for vertical countermovement jump variables. J Strength Cond Res 38(6): 1144–1148, 2024—The aim of this study was to determine the criterion validity of the Hawkin Dynamics (HD) wireless dual force platform system for assessing vertical countermovement jump (CMJ) variables, compared with those derived from a Kistler piezoelectric laboratory grade force platform system. During a single testing session, HD force platforms were placed directly on top of 2 adjacent Kistler force platforms to simultaneously collect vertical ground reaction forces produced by 2 male recreational soccer players (age: 29.0 ± 2.8 years, height: 1.79 ± 0.01 m, mass: 85.6 ± 4.7 kg) that performed 25 vertical CMJs each. Sixteen vertical CMJ variables pertaining to jump height (JH), flight time (FT), time-to-take off (TTT), countermovement depth, body weight (BW), propulsive and braking mean, and peak powers, forces, and impulses were compared between systems. Fixed bias was observed for 6 of 16 variables (peak and mean braking power, mean propulsion force, TTT, FT, and BW), while proportional bias was present for 10 of 16 variables (peak and mean propulsive and braking force, TTT, FT, peak and mean braking power, mean propulsive power, and BW). For all variables regardless of fixed or proportional bias, percentage differences were ≤3.4% between force platform systems, with near perfect to perfect correlations (r or ρ = 0.977–1.000) observed for 15 of 16 variables. The HD dual wireless force platform system can be considered a valid alternative to a piezoelectric laboratory grade force platform system for the collection of vertical CMJ variables, particularly outcome (i.e., JH, reactive strength index modified) and strategy variables (countermovement depth).
Muscle Strength Preservation During Repeated Sets of Fatiguing Resistance Exercise: A Secondary Analysis
Authors: Nuzzo James L. 
Published: May 2024

Abstract
Nuzzo, JL. Muscle strength preservation during repeated sets of fatiguing resistance exercise: A secondary analysis. J Strength Cond Res 38(6): 1149–1156, 2024—During sustained or repeated maximal voluntary efforts, muscle fatigue (acute strength loss) is not linear. After a large initial decrease, muscle strength plateaus at approximately 40% of baseline. This plateau, which likely reflects muscle strength preservation, has been observed in sustained maximal isometric and repeated maximal isokinetic contractions. Whether this pattern of fatigue occurs with traditional resistance exercise repetitions with free weights and weight stack machines has not been overviewed. Here, the aim was to determine whether the number of repetitions completed across 4 or more consecutive repetitions-to-failure tests exhibits the same nonlinear pattern of muscle fatigue. A secondary analysis was applied to data extracted as part of a recent meta-analysis on repetitions-to-failure tests. Studies were eligible if they reported mean number of repetitions completed in 4–6 consecutive repetitions-to-failure tests at a given relative load. Twenty-nine studies were included. Overall, the results show that the number of repetitions completed in consecutive repetitions-to-failure tests at a given load generally decreases curvilinearly. The numbers of repetitions completed in sets 2, 3, 4, 5, and 6 were equal to approximately 70, 55, 50, 45, and 45% of the number of repetitions completed in set 1, respectively. Longer interset rest intervals typically attenuated repetition loss, but the curvilinear pattern remained. From the results, a chart was created to predict the number of repetitions across 6 sets of resistance exercise taken to failure based on the number of repetitions completed in set 1. The chart is a general guide and educational tool. It should be used cautiously. More data from a variety of exercises, relative loads, and interset rest intervals are needed for more precise estimates of number of repetitions completed during repeated sets of fatiguing resistance exercise.
METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation of MET in endometriosis
Authors: Xiong Wenqian , Jin Jie , Liu Yi 
Published: May 2024

In brief
Failure to induce mesenchymal–epithelial transition (MET) during stromal cell decidualization can lead to consequences such as impaired fertility in patients with endometriosis. METTL3-mediated m6A modification plays an important role in attenuating MET and defective decidualization of endometrial stromal cells and contributes to the development of reduced endometrial receptivity in endometriosis.

Abstract
Mesenchymal–epithelial transition (MET)-mediated endometrial decidualization is pivotal for achieving endometrial receptivity and successful pregnancy. We observed blockade of MET in the eutopic secretory endometrium of patients with endometriosis, but the underlying mechanism is unknown. In this study, real-time PCR was used to detect PRL and IGFBP1 expression, whereas western blotting was used to detect the expression of MET markers and METTL3. Phalloidin staining was used to identify changes in cell morphology. M6A levels were quantified using a colorimetric method and m6A dot blots, and functional analysis was performed using spheroid adhesion assays. We first found that increased E-cadherin expression was accompanied by decreased vimentin and Slug expression in the eutopic secretory endometrium of individuals with endometriosis. We also detected a significant increase in both the m6A level and the expression of the related methyltransferase METTL3. Finally, METTL3 expression was negatively correlated with PRL, IGFBP1, and MET markers expression. Collectively, our findings suggest that METTL3 mediates m6A modification, thereby inhibiting MET formation within the eutopic secretory endometrium of patients with endometriosis. Increased METTL3-mediated m6A modification plays a crucial role in attenuating MET formation and decidualization impairment in endometrial stromal cells, ultimately contributing to compromised endometrial receptivity in individuals with endometriosis. These insights could lead to the identification of potential therapeutic targets for improving both endometrial receptivity and pregnancy rate among individuals affected by endometriosis.
Global Health Education in Pediatric Hospital Medicine Fellowships in the United States
Authors: Lenzen Christiane , Coria Alexandra L. , Hofto Meghan E. , Pitt Michael B. , Cheng Frances Y. , Mediratta Rishi P. 
Published: May 2024

BACKGROUND AND OBJECTIVESPediatric fellows across all subspecialties are interested in global health (GH). Little is known about how GH is incorporated into Pediatric Hospital Medicine (PHM) fellowships. Our objective was to examine the current landscape of GH education in PHM fellowships.METHODSIn 2022, we conducted a cross-sectional electronic survey of PHM fellowship directors (FDs), current fellows, and recently graduated fellows (alumni) via e-mail and listservs. Surveys asked about GH education (curriculum, electives, and research) in PHM fellowships, barriers to GH training, and fellow interest in GH.RESULTSResponse rates were 56% (34/61) among PHM FDs, 57% (102/178) among fellows, and 29% (59/206) among alumni. Most fellows (73%) and alumni (59%) were interested in GH electives. Although 53% of FDs reported offering GH electives, a minority of fellows (21%) and alumni (19%) reported being offered GH electives (P &lt;.001). Few FDs reported offering a GH curriculum (9%), although most fellows (63%) and alumni (50%) expressed interest. Of the 16 FDs without GH electives, 81% planned to offer them. Cited barriers included a lack of GH curricula, insufficient funding, competing educational demands, and a lack of international partnerships. More FDs (82%) than fellows (64%) and alumni (45%) agreed that GH education improves overall fellow education (P = .01). Similarly, more FDs (75%) than fellows (56%) and alumni (38%) agreed that offering GH education improves recruitment (P = .002).CONCLUSIONSThere is an unmet demand for GH education in PHM fellowships, and fellows may not be aware of GH opportunities.
The Integration of ICT in ELT of Pre-Service Teacher Professional Education (PPG) Students
Authors: Dewi Ifti Luthviana , Priyana Joko 
Published: May 2024

Student teachers are expected to take advantage the use of technology for teaching process. This study aims to investigate the ICT tools used by Pre-service English Teachers who are also PPG students to achieve their learning goals in teaching English during their Teaching Practicum (PPL), how they integrate these ICT tools evaluated by TPACK and SAMR framework, and examine the obstacles. This current study was descriptive qualitative research. In this research design, the data was gathered by means of document analysis, semi-structured interview and observation. The participants were five Pre-Service Teacher Professional Education (PPG) Students majoring English Education Batch 2 academic year 2022/2023 in one of university in Yogyakarta, who represented three school levels (SMP, SMA and SMK). The data were in three distinct stages: reduction or condensation, data display, and conclusion drawing or verification. The result shows that (1) variety of ICT tools are used to achieve the learning goals, they are Google Form, Google Docs, WhatsApp, Canva, Blooket, Bamboozle, WordWall, Kahoot, Quizizz, YouTube, and GimKit. These tools are selected based on the learning needs, students’ need, students’ preferences, learning objectives, availability of facility, and possible challenges. (2) The activities that integrating ICT tools majority are in augmented level of SAMR. While the pre-services teachers’ TPACK is effectively help them in integrating ICT tool to enhance the quality of learning, but still need optimization. (3) There are three main obstacles faced by the teachers; which come from the technical problems, teachers’ TPACK, and students’ problem. Technical problems covers the lack of internet access, insufficient devices, and restrictive school rules. Teachers’ challenge on their TPACK includes the selection of suitable tools, the time management in integrating ICT tools, and the struggle to keep up with the rapid development of technology. The students face no significant problems, yet sometimes the negligence of the task arises as they become too attached with the ICT tools.
Anthrax: Distribution, Knowledge, Attitude and Practice Towards Pastoralists in Jawhar, Qalimow and Adan Yabal Somalia.
Authors: Barre Abdirahman , Hassan Abdihamid Salad , Mohamed Abdullahi Nur 
Published: May 2024

Anthrax is a Zoonotic Disease (both Human and Animals) the disease is causing higher morbidity and mortality rate in Middle-Shebelle Somalia. Anthrax is a rare infectious disease caused by the bacterium Bacillus anthraces. It was reported in many parts of the region the disease is endemic that effects production with the pastoralists with an incidence >30% of their livestock production system. In a study to determine the status of anthrax in pastoralists in three selected area of Middle-Shebelle: Jawhar, Qalimow, and Aaden yabaal with Forty two herds were also used. The three selected area of the study were the most livestock populations in Middle-Shebelle. A structured Questionnaire was used to capture pastoralists Knowledge, Attitude and Their Practice with regards of Anthrax Disease. A cross-sectional survey was conducted contemporaneously with focus group discussions (FGDs) and key Informant interviews (KIIs) between May 2020 and April 2021. A Four Hundreds (4OO) of Households were visited via Personal interview. The existence of the disease per herd were estimated that 18.1% of camel herds, 34.3% of cattle herds and 47.6% of small ruminants flocks. Thus the summary of the KAP Results indicated that there was lack of Knowledge and Practice Gap among pastoralists related anthrax Disease. Generally, majority of farmers were practicing poorly in livestock community that was created the distribution of the disease. Therefore, the cattle sheep and goat herds should aware the diseases about the characterization and controlling systems through extending and trading for pastoralists and households. In addition, further assessment and control coverage with anthrax disease will highly option of essentials.
Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia (AcuPA Study). A Nationwide Survey in Poland
Authors: Morawiak Anna , Salamonowicz Małgorzata , Królak Aleksandra , Kałwak Krzysztof , Owoc-Lempach Joanna , Kowalczyk Jerzy , Zawitkowska Joanna , Szczepański Tomasz , Irga-Jaworska Ninela , Adamkiewicz-Drożyńska Elżbieta , Albrecht Katarzyna , Szmydki-Baran Anna , Balwierz Walentyna , Czogała Małgorzata , Wachowiak Jacek , Derwich Katarzyna , Młynarski Wojciech , Zalewska-Szewczyk Beata , Krawczuk-Rybak Maryna , Sawicka- Żukowska Małgorzata , Styczyński Jan , Kołtan Andrzej , Safranow Krzysztof , Urasiński Tomasz , Ociepa Tomasz 
Published: May 2024

Purpose: This study aimed to identify the risk factors for acute pancreatitis (AP) and its impact on outcomes in Polish children treated for ALL. Methods: The study group included 2303 children who received intensive chemotherapy for ALL. The group was subdivided into patients with at least one episode of AP and those who did not develop AP following treatment for ALL. Results: The cumulative incidence of AP in the study group was 4.08%. Older age was an independent risk factor for AP development (OR 1.05; 95%CI: 1.006 – 1.098; p=0.03). The overall mortality related to AP was 2.13%. The probabilities of disease-free survival (p-DFS) and event-free survival (p-EFS) were 0.84 vs. 0.86, log-rank: p=0.65 and 0.75 vs. 0.80, log-rank: p=0.12, respectively in both subgroups. A total of 22 out of 94 patients (23.4%) with AP were re-exposed to asparaginase (ASP) during the subsequent phases of the treatment. Only one re-exposed to ASP patient (4.5%) developed a second episode of AP. There were no significant differences in p-DFS and p-EFS between patients re-exposed and not re-exposed to asparaginase (0.78 vs. 0.86, log-rank p=0.27 and 0.63 vs. 0.79, log-rank p=0.09 respectively). Conclusions: The incidence of AP in children with ALL is low and related to the patient’s age. AP development doesn’t seem to impact p-DFS and p-EFS in children with ALL. The recurrence of AP following re-exposure to asparaginase in patients with ALL and a history of AP is low (4.5%). Re-exposure to asparaginase after the first episode of AP doesn’t improve either p-DFS or p-EFS in children with ALL.
Readability Analysis of Spanish-Language Patient-Reported Outcome Measures in Orthopaedic Surgery
Authors: Garavito Jorge A. , Rodarte Patricia , Navarro Ronald A. 
Published: May 2024

Background:
Patient-reported outcome measures (PROMs) are increasingly used to quantify patient symptomatology when assessing intervention effectiveness as well as to guide patient-centered health-care management and research. Previous studies have analyzed the readability of PROMs used in orthopaedics in the English language; however, the readability of PROMs used in orthopaedics in the Spanish language has not been evaluated. Given the increasing number of Spanish-speaking individuals seeking orthopaedic care in the United States, it is imperative that PROMs are at an adequate reading level for patients to answer appropriately in their native language. This study aimed to assess the readability of publicly available Spanish-language PROMs used in orthopaedics.

Methods:
Searches of the PubMed, Google Scholar, and Embase databases were conducted to identify publicly available Spanish-language versions of PROMs used in orthopaedics. Additionally, the PROMIS Health Organization was contacted to obtain Spanish-language versions of the PROMIS (Patient-Reported Outcomes Measurement Information System) questionnaires. A total of 42 Spanish-language PROMs were identified and included in this study. The text of each PROM was inserted into multilingual readability software (legible.es), which analyzed the readability of each PROM using the Fernández Huerta and Índice de Legibilidad de Flesch-Szigriszt (INFLESZ) readability formulas. The mean and standard deviation (SD) of the raw readability scores were calculated for the PROMs. The percentage of PROMs at or below the 6th-grade reading level was also calculated.

Results:
The mean readability of PROMs using the INFLESZ formula was at a 7th to 10th-grade reading level (mean = 63, SD = 16), and the mean readability using the Fernández Huerta formula was 68 (SD = 15). On average, 57% of the PROMs used in orthopaedics were at or below the INFLESZ 6th-grade readability level.

Conclusions:
Approximately half of Spanish-language PROMs used in orthopaedics are written at a reading level that does not meet the National Institutes of Health and the American Medical Association recommendations at or below the 6th-grade level. PROM developers and translators should consider the importance of readability when translating PROMs, to maximize their use and efficacy among orthopaedic patients speaking that language.
Enhancement of the Consistency and Connectivity of the Ant-tracking Algorithm via 3D U-Net with Dual-Threshold Iteration
Authors: Choi Seunghun , Lee Min Je , Jung Yonggwon , Lee Juan , Kim Jineon , Cho Yongchae 
Published: May 2024

Abstract
The ant-tracking algorithm is commonly used to extract faults in geological structures. However, obtaining 3D ant-tracking data requires the calculation of various volume attributes. To obtain satisfactory data, it is necessary to iterate through the parameters of these attributes to achieve reasonable continuity. Moreover, due to the numerous parameters involved, the algorithm can produce different outputs with each execution. In this study, we aimed to enhance the performance of the ant-tracking algorithm by combining it with a basic U-Net structure. The input and corresponding labels to the model are "cubic shaped" 3D data segmented from the original 3D seismic volume to facilitate cross-validation with distinct regions. We used the label data as the single ant-tracking result to minimize the operator’s bias by executing the ant-tracking with several different parameters and executors and then taking the average. An evaluative comparison of three different loss functions (MAE, RMSE, and MSE) was conducted to identify the optimal function for training the model. Across five out of the six metrics, MSE function demonstrated predominant performance, leading to its adoption. Apart from this, a significant number of misinterpreted faults led us to propose the post-processing algorithm named "Dual-Threshold Iteration." It was initially used to extract fine blood vessels branching out from large vessels in medical image segmentation and adapted in our work to ensure a high level of continuity while ignoring worthless noise. Comparison with the F1 score and the number of 3D-connected components confirmed that the proposed method could generate reduced bias and smoothly connected fault structures.