bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robotic transanal minimally invasive surgery (R-TAMIS): current evidence in the treatment of early rectal neoplasia
Authors: O’Sullivan Niall J. , Temperley Hugo C. , Larkin John , McCormick Jacob J. , Rausa Emanuele , McCormick Paul , Heriot Alexander , Mehigan Brian J. , Warrier Satish , Kelly Michael E. 
Published: May 2024

Abstract
Introduction
Robotic transanal minimally invasive surgery (R-TAMIS) was introduced in 2012 for the excision of benign rectal polyps and low grade rectal cancer. Ergonomic improvements over traditional laparoscopic TAMIS (L-TAMIS) include increased dexterity within a small operative field, with possibility of better surgical precision. We aim to collate the existing data surrounding the use of R-TAMIS to treat rectal neoplasms from cohort studies and larger case series, providing a foundation for future, large-scale, comparative studies.

Methods
Medline, EMBASE and Web of Science were searched as part of our review. Randomised controlled trials (RCTs), cohort studies or large case series (≥ 5 patients) investigating the use of R-TAMIS to resect rectal neoplasia (benign or malignant) were eligible for inclusion in our analysis. Quality assessment of included studies was performed via the Newcastle Ottawa Scale (NOS) risk of bias tool. Outcomes extracted included basic participant characteristics, operative details and histopathological/oncological outcomes.

Results
Eighteen studies on 317 participants were included in our analysis. The quality of studies was generally satisfactory. Overall complication rate from R-TAMIS was 9.7%. Clear margins (R0) were reported in 96.2% of patients. Local recurrence (benign or malignant) occurred in 2.2% of patients during the specified follow-up periods.

Conclusion
Our review highlights the current evidence for R-TAMIS in the local excision of rectal lesions. While R-TAMIS appears to have complication, margin negativity and recurrence rates superior to those of published L-TAMIS series, comparative studies are needed.
Effect of a higher protein diet and lifestyle camp intervention on childhood obesity (The COPE study): results from a nonrandomized controlled trail with 52-weeks follow-up
Authors: Jakobsen Dorthe D. , Brader Lea , Bruun Jens M. 
Published: May 2024

Abstract
Purpose
In adults, diets rich in protein seem beneficial in relation to satiety, weight loss, and weight management; however, studies investigating dietary protein and weight development in children are scarce and inconsistent. This nonrandomized controlled trial aimed to investigate the effect of a higher protein diet during lifestyle intervention on anthropometry and metabolic biomarkers in children with overweight and obesity.

Methods
Children (n:208) were recruited from two multicomponent lifestyle camps. One camp was assigned as the intervention group. In the intervention group, carbohydrates-rich foods at breakfast and two in-between-meals were replaced with protein-containing foods to increase the amount of protein from ~ 10–15 energy percent (E%) per day to ~ 25E% per day. Other components were similar between groups. Anthropometry and biochemical measurements were collected at baseline, 10 weeks (after camp) and 52 weeks.

Results
The intervention group had a non-significant improvement in BMI-SDS (− 0.07 SD (− 0.19; 0.05), p = 0.24) compared to the control group, but in general, there was no effect of a higher protein diet on anthropometry and metabolic biomarkers. Overall, 10 weeks at camp resulted in a more favorable body composition [− 6.50 kg (p < 0.00), − 0.58 BMI-SDS (p < 0.00), and − 5.92% body fat (p < 0.00)], and improved metabolic health, with most changes maintained at 52 weeks.

Conclusion
A higher protein diet had no significant effect on body composition and metabolic health; however, these lifestyle camps are an efficiatious treatment strategy for childhood obesity.
Clinical trial registration: clinicaltrials.gov with ID: NCT04522921. Preregistered August 21st 2020.
Diagnostics of allergic rhinitis under dupilumab therapy
Authors: Huber Patrick , Gröger Moritz , Stihl Clemens , Frankenberger Hanna , Bertlich Mattis , Haubner Frank , Gellrich Donata 
Published: May 2024

Abstract
Background
Allergic rhinits is a prevalent condition, affecting a substantial proportion of the population. This study investigates the impact of ongoing biologic therapy, specifically with Dupilumab, on allergy diagnostics in patients with allergic rhinits.

Methods
Various tests, including the Skin Prick Test, serum IgE levels and Allergy Screening Panels, were examined for their effectiveness in detecting sensitizations during biologic treatment.

Results
The results indicate a significant decline in total IgE levels following biologic therapy initiation, aligning with previous findings on Dupilumab's inhibitory effects on IL-4 and IL-13. However, the specific IgE to total IgE ratio for major allergens was not significantly reduced. Comparing diagnostic tools, the Skin Prick Test demonstrates an impressive retention rate of sensitizations (98%) during Dupilumab treatment, outperforming the Allergy Screening Panel, which shows a 75% detection rate. Notably, the panel displays limitations in capturing lower sensitization levels.

Conclusion
In summary, this study underscores that, despite the influence of biologic therapy on certain markers, standard allergy tests remain viable while emphasizing the importance of considering specific IgE levels rather than relying solely on CAP classes. The Skin Prick Test in particular proves to be a reliable tool for identifying sensitizations during Dupilumab treatment. The results offer valuable guidance for the diagnostic management of Allergic rhinits in individuals subjected to Dupilumab treatment.
Foot and ankle problems in children and young people: a population-based cohort study
Authors: Rezel-Potts Emma , Bowen Catherine , Dunn Kate M. , Jones Christopher I. , Gulliford Martin C. , Morrison Stewart C. 
Published: May 2024

AbstractThe aim of this research was to describe the epidemiology, presentation and healthcare use in primary care for foot and ankle problems in children and young people (CYP) across England. We undertook a population-based cohort study using data from the Clinical Practice Research Datalink Aurum database, a database of anonymised electronic health records from general practices across England. Data was accessed for all CYP aged 0–18 years presenting to their general practitioner between January 2015 and December 2021 with a foot and/or ankle problem. Consultation rates were calculated and used to estimate numbers of consultations in an average practice. Hierarchical Poisson regression estimated relative rates of consultations across sociodemographic groups and logistic regression evaluated factors associated with repeat consultations. A total of 416,137 patients had 687,753 foot and ankle events, of which the majority were categorised as “musculoskeletal” (34%) and “unspecified pain” (21%). Rates peaked at 601 consultations per 10,000 patient-years among males aged 10–14 years in 2018. An average practice might observe 132 (95% CI 110 to 155) consultations annually. Odds for repeat consultations were higher among those with pre-existing diagnoses including juvenile arthritis (OR 1.73, 95% CI 1.48 to 2.03). Conclusions: Consultations for foot and ankle problems were high among CYP, particularly males aged 10 to 14 years. These data can inform service provision to ensure CYP access appropriate health professionals for accurate diagnosis and treatment.

What is Known:• Foot and ankle problems can have considerable impact on health-related quality of life in children and young people (CYP).• There is limited data describing the nature and frequency of foot and ankle problems in CYP.

What is New:• Foot and ankle consultations were higher in English general practice among CYP aged 10 to 14 years compared to other age groups, and higher among males compared to females.• The high proportion of unspecified diagnoses and repeat consultations suggests there is need for greater integration between general practice and allied health professionals in community-based healthcare settings.
Weight loss, glycolipid profile changes in type 2 diabetes patients after esophagectomy: a propensity score matching analysis
Authors: Yang Jingrong , Lai Jiabin , Chen Xiangrui , Xia Wenxuan , Li Yaxin , Huang Jialei , Wang Yu 
Published: May 2024

Abstract
Background
Type 2 diabetes mellitus (T2DM) is a common co-morbidity in patients who receive esophagectomy and has unfavorable effects on glucose and lipid metabolism in patients. This study examines how weight and glycolipid metabolism change in patients with T2DM following esophagectomy.

Methods
This retrospective, one-center, observational analysis with a propensity score matching analysis (PSM) included 114 patients who underwent esophageal surgery in the Department of Cardiothoracic Surgery, the 900th Hospital of Joint Logistic Support Force from 2017 to 2020, which were separated into T2DM group and Non-T2DM group. Weight, body mass index (BMI), fasting plasma glucose (FPG), triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were measured and analyzed before and after the operation.

Results
Two groups showed similar reductions in weight and BMI after surgery. In the T2DM group, weight decreased from 63.10(10.31) before surgery to 55.10(11.60) kg at 6 months (P < 0.001) with BMI decreasing from 22.67 (2.90) to 19.77 (3.48); While in the Non-T2DM group, weight decreased from 61.42 (8.46) to 53.19 (9.26) kg at 6 months after surgery with BMI decline from 22.49 (2.77) before operation to 19.45 (3.08) at 6 months after surgery. Fasting plasma glucose levels showed a significant decrease (P = 0.035) in the T2DM group at a six-month point of 7.00 (2.21) mmol/L compared to preoperative levels of 7.67 (2.32) mmol/L. HDL levels increased significantly in the Non-T2DM group at six months postoperatively at 1.52 (0.05) with P < 0.001 compared to preoperative levels of 1.22(0.04) mmol/L. TG, LDL, and TC levels decreased significantly in both groups from the preoperative to the 6-month point.

Conclusions
Esophagectomy induces weight loss in T2DM and Non-T2DM groups, improves long-term glucose metabolism in the T2DM group, and enhances lipid metabolism in both groups. Further research is needed to understand their mechanisms.
False springs in the Netherlands: climate change impact assessment with the false spring damage indicator model
Authors: Bosdijk Joep , de Feiter Vincent S. , Gaiser Annika , Smink Thijs , Thorkelsdottir Gudrun , van Vliet Arnold J. H. , Luedeling Eike 
Published: May 2024

AbstractStrong night frosts in spring have the potential to cause severe damage to fruit trees, causing up to €3.3 billion of damage in Europe in 2017. If temperatures drop below − 2.2 °C after the growing season starts, this phenomenon is referred to as a false spring. For the Netherlands, the risk of false spring damage increased during the past 70 years, due to the decreasing time between the last strong night frost and the flower budburst. This raises the question of whether this trend will continue under future influences of climate change. To analyse the development of false spring damage risks, we developed the False Spring Damage Indicator (FSDI) model. Applying this model to the Dutch KNMI’14 climate change scenarios for 2050 and 2085 showed a decrease in false spring damage risk. The historical risk for 60% bud damage was reduced to around 40% for the moderate scenario in 2050 and to less than 15% for the severe scenario in 2050 and all scenarios in 2080. False spring damage varied spatially throughout the Netherlands. Currently, more severe damage can be expected in the east, while coastal regions in the north and west are less prone to false spring damage. In the future, this is expected to become more uniform over the Netherlands, as the risk in the east is predicted to decrease strongly, becoming similar to the low damage risk in the coastal regions.
Reduced Variance Random Batch Methods for Nonlocal PDEs
Authors: Pareschi Lorenzo , Zanella Mattia 
Published: May 2024

AbstractRandom Batch Methods (RBM) for mean-field interacting particle systems enable the reduction of the quadratic computational cost associated with particle interactions to a near-linear cost. The essence of these algorithms lies in the random partitioning of the particle ensemble into smaller batches at each time step. The interaction of each particle within these batches is then evolved until the subsequent time step. This approach effectively decreases the computational cost by an order of magnitude while increasing the amount of fluctuations due to the random partitioning. In this work, we propose a variance reduction technique for RBM applied to nonlocal PDEs of Fokker-Planck type based on a control variate strategy. The core idea is to construct a surrogate model that can be computed on the full set of particles at a linear cost while maintaining enough correlations with the original particle dynamics. Examples from models of collective behavior in opinion spreading and swarming dynamics demonstrate the great potential of the present approach.
The role of sheltered habitats in biodiversity conservation of species sensitive to drought: a case study using ground beetles (Coleoptera, Carabidae) in the Gorongosa National Park
Authors: Baptista Martim , Carvalho Rui , Boieiro Mário , Bartz Marie , Mendes Sara , Timóteo Sérgio , Azevedo-Pereira Henrique M.V.S. , Alves Joana , Alves da Silva António , Briones Maria J.I. , Serrano Artur R.M. , Sousa José Paulo , Martins da Silva Pedro 
Published: May 2024

AbstractIn the aftermath of 2019’ tropical cyclones Idai and Kenneth, we assessed ground beetle communities of the Gorongosa National Park (GNP) in Mozambique. The influence of habitat shelters, namely the buffering role of closed microhabitat conditions on Alpha diversity and community trait values during a long period of drought, was evaluated across the main habitat types of the park: miombo forests, mixed forests, transitional forests, and grasslands (open savannas). These habitat types comprised a distance gradient in relation to lake Urema, in the center of GNP. Miombo forests were farther from the lake while grasslands and transitional forests were in the floodplain area. Ground beetle communities were sampled using pitfall traps set up at 25 sites of each habitat type along an environmental gradient of tree canopy cover during the last twenty days of the dry season. Higher species richness of ground beetles was found in closed habitat shelters along the distance gradient to lake Urema. A higher functional diversity was also found along the canopy gradient, with larger sized and wingless species being more abundant in closed habitats than in open areas. This result highlights the crucial role of habitat closedness in the protection of sensitive ground beetles. In particular, the buffer effect of tree canopy and the protection of the understory plants and the litter layer was critical for the survival of hygrophilous species and will be key in conservation strategies to face climate aridification and habitat fragmentation.
An Analytic Element Model for Seepage Forces in Fractured Media
Authors: Toller Erik A. L. , Strack Otto D. L. 
Published: May 2024

AbstractThere are many situations where groundwater flow has high flow rates, causing large seepage forces. Examples are flows around highly conductive fractures and tunnels. We present a new analytic element for a tunnel in an elastic medium. We combined the analytic element method for groundwater flow with that for linear elasticity, and include the seepage force as a body force in the linearly elastic model. We represent tunnels and fractures as analytic elements. The solution for the case considered is limited to steady state flow and fluid-to-solid coupling. We present examples of the computed seepage forces around a tunnel and a fracture as well as a comparison with another numerical model.
The impact of artificial intelligence in the early retirement decision
Authors: Casas Pablo , Román Concepción 
Published: May 2024

AbstractThis paper examines the impact of Artificial Intelligence (AI) on early retirement (ER) decisions in Europe. For the analysis, we utilize microdata from the Survey of Health, Ageing and Retirement in Europe, along with occupation-level data on AI advances and AI exposure. Initially, we investigate the influence of AI advances and AI exposure separately, finding in both instances a significant reduction in ER likelihood, though this only applies to workers with higher education. Subsequently, we explore the interaction between AI advances and AI exposure concerning ER probability. This interaction proves critical in determining AI’s impact on ER transitions. Specifically, we observe a significant reduction in ER probabilities for workers whose occupations exhibit high levels of AI advances and high expectations for further implementation of this technology in the future. Finally, we jointly analyse the interaction between AI advances, AI exposure, and education level. This analysis highlights that workers’ ER probabilities may either increase or decrease in response to the AI revolution, depending on their education level and the characteristics of their occupations in terms of AI advances and AI exposure.
Design and validation of the perception of risk towards environmental unsustainability scale (PREUS)
Authors: Cuadrado E. , Molero-Jarilla E. M. , Muñoz-García I. M. , Torres-Porras J. , Alcántara-Manzanares J. 
Published: May 2024

AbstractNo validated scales are available to assess the perception of risk towards environmental unsustainability (PREU), which is a key construct for the adoption of sustainable behaviors. To fill this literature gap, the objective of this study was to develop and validate the PREU scale (PREUS). To this end, a total of 519 Spanish participants answered a survey composed of the PREUS and other psychosocial variables. The exploratory and confirmatory factor analyses ratify the bifactorial structure of the scale. The two factors refer to perceived risk to oneself and one’s own family (anthropocentric view of risk), and risk for the planet (ecocentric view), respectively. The structural equation modelling analyses confirmed (1) the expected relationships between both factors and other constructs of their nomological network, and (2) the mediating role of the ascription of responsibility in the relationship established between risk perception and sustainable behavior, offering empirical support for the external validity of the scale. Finally, both metric and scalar gender invariance were granted and, as expected, women showed higher PREU than men. The study provides a brief, easy-to-complete, reliable, valid, and sex-invariant instrument that can be useful for researchers and educators to assess the extent to which individuals perceive the risk that environmental unsustainability can pose.
Intersection bodies of polytopes: translations and convexity
Authors: Brandenburg Marie-Charlotte , Meroni Chiara 
Published: May 2024

AbstractWe continue the study of intersection bodies of polytopes, focusing on the behavior of IP under translations of P. We introduce an affine hyperplane arrangement and show that the polynomials describing the boundary of $$I(P+t)$$

I
(
P
+
t
)

can be extended to polynomials in variables $$t\in \mathbb {R}^d$$

t
∈

R

d

within each region of the arrangement. In dimension 2, we give a full characterization of those polygons such that their intersection body is convex. We give a partial characterization for general dimensions.
Older Chinese and Filipino American Immigrants with Type 2 Diabetes and their Adult Child: A Qualitative Dyadic Exploration of Family Support
Authors: Peregrina Hillary Nicole , Bayog Maria L. G. , Pagdilao Adam , Bender Melinda S. , Doan Therese , Yoo Grace J. 
Published: May 2024

AbstractType 2 Diabetes (T2D) among older Asian American immigrants (AA) is a growing concern. Asian Americans represent 9% of diagnosed diabetes. Very little is known on how older Asian American immigrants with T2D navigate diabetes management, in particular the role of family support. This qualitative study examines Chinese and Filipino Americans, the two largest Asian subgroups in the US (4.2 million, and 3.6 million, respectively), and family support dynamics among adult children and their parents diagnosed with T2D. Ten dyads (n = 20) made up of adult children and aging parents participated in in-depth and dyadic interviews. Results indicate that family support occurs in a trajectory of stages. The following thematic patterns emerged in these dyads around support: independence, transitions, partnership, and stepping in. The findings point to various supportive stages that Asian American adult children and aging parents with T2D experience and the importance of developing supportive interventions for both adult children and aging parents at these various stages.
Photosensitive properties of Schottky type photodiodes prepared by spin coating of isoniazid Schiff base thin film on p-Si
Authors: Tezcan Ali Osman , Oruç Pınar , Tuğluoğlu Nihat , Eymur Serkan 
Published: May 2024

AbstractIn this study, a layer of isonicotinohydrazide and pyrene-based Schiff base (PyMIs) was formed on the front side of a p-Si semiconductor using the spin coating method, and an Al/PyMIs/p-Si/Al diode was fabricated. The I-V characteristics of the fabricated diode were measured under dark and from 20 to 100 mW/cm2 illumination intensities for both forward and reverse bias. Diode parameters, including saturation current ($${I}_{0}$$), ideality factor (n), and barrier height ($${\varphi }_{b}$$) were investigated for all measurements based on thermionic emission theory. The values n changed from 2.51 to 2.05, and the $${\varphi }_{b}$$ changed from 0.77 eV to 0.86 eV as light intensity increased from dark to 100 mW/cm2. The series resistance ($${R}_{s}$$) values of the diode were investigated using the modified Norde’s function and Cheung’s functions. An analysis of the forward $$log\left( I \right) - log\left( V \right)$$ plot of Al/PyMIs/p-Si (MOmS)-type diode specified the carrier transport domination by ohmic conduction in the lower bias regions, by the space-charge-limited current (SCLC) at medium bias regions and the trap-charge limit current (TCLC) transport mechanism at higher bias regions. The fabricated diode exhibited typical photodiode behavior with reverse current values increasing from 9.13 × 10− 6 A to 1.05 × 10− 4 A, respectively. Furthermore, $$I-V$$ characteristics illuminated from 20 to 100 mW/cm2 were also studied, and they indicated that the Al/PyMIs/p-Si diode could operate in a photovoltaic regime.