bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Chatbot-Delivered Stress Management Coaching for Students (MISHA App): Pilot Randomized Controlled Trial
Authors: Ulrich Sandra , Lienhard Natascha , Künzli Hansjörg , Kowatsch Tobias 
Published: May 2024

Background
Globally, students face increasing mental health challenges, including elevated stress levels and declining well-being, leading to academic performance issues and mental health disorders. However, due to stigma and symptom underestimation, students rarely seek effective stress management solutions. Conversational agents in the health sector have shown promise in reducing stress, depression, and anxiety. Nevertheless, research on their effectiveness for students with stress remains limited.

Objective
This study aims to develop a conversational agent–delivered stress management coaching intervention for students called MISHA and to evaluate its effectiveness, engagement, and acceptance.

Methods
In an unblinded randomized controlled trial, Swiss students experiencing stress were recruited on the web. Using a 1:1 randomization ratio, participants (N=140) were allocated to either the intervention or waitlist control group. Treatment effectiveness on changes in the primary outcome, that is, perceived stress, and secondary outcomes, including depression, anxiety, psychosomatic symptoms, and active coping, were self-assessed and evaluated using ANOVA for repeated measure and general estimating equations.

Results
The per-protocol analysis revealed evidence for improvement of stress, depression, and somatic symptoms with medium effect sizes (Cohen d=−0.36 to Cohen d=−0.60), while anxiety and active coping did not change (Cohen d=−0.29 and Cohen d=0.13). In the intention-to-treat analysis, similar results were found, indicating reduced stress (β estimate=−0.13, 95% CI −0.20 to −0.05; P<.001), depressive symptoms (β estimate=−0.23, 95% CI −0.38 to −0.08; P=.003), and psychosomatic symptoms (β estimate=−0.16, 95% CI −0.27 to −0.06; P=.003), while anxiety and active coping did not change. Overall, 60% (42/70) of the participants in the intervention group completed the coaching by completing the postintervention survey. They particularly appreciated the quality, quantity, credibility, and visual representation of information. While individual customization was rated the lowest, the target group fitting was perceived as high.

Conclusions
Findings indicate that MISHA is feasible, acceptable, and effective in reducing perceived stress among students in Switzerland. Future research is needed with different populations, for example, in students with high stress levels or compared to active controls.

Trial Registration
German Clinical Trials Register DRKS 00030004; https://drks.de/search/en/trial/DRKS00030004
La mediación lúdico-pedagógica usada como herramienta de apropiación social de conocimiento. Resultado del proyecto de investigación Capaz de la Universidad Católica de Pereira
Authors: Betancurth Becerra Carlos Mario , Linares Andrés Felipe 
Published: May 2024

La apropiación social del conocimiento es una herramienta que viene adquiriendo mayor relevancia en el campo de la investigación, debido a la necesidad de divulgación, comunicación y adquisición integral de los saberes producidos por la investigación hacia las comunidades. En el ámbito de la investigación social y de la comunicación, la apropiación social de conocimientos es vital porque permite generar estrategias que ponen el conocimiento en circulación con las comunidades intervenidas.

Una de esas estrategias generadas y estudiadas en este artículo, es lo referente a la dimensión lúdica y pedagógica, que nos permite que abrir la posibilidad de crear ambientes y contexto comunicativos diferentes de aprendizaje a través del juego como dispositivo para de transferencia y comunicación saberes producidos en los procesos de investigación con las comunidades.

Cabe decir, que el marco de investigación que sirve de reflexión para este documento, se ubica en el método de investigación CAPAZ (Centro Analítico de producciones culturales) de la Universidad Católica de Pereira, que orienta en sus investigaciones la aplicación del BigData y la Lexicometría automatizada para luego producir narrativas pedagógicas alrededor de las temáticas investigadas en proyectos como, 1.RUTAS (Relatos universitarios del conflicto en Colombia); 2. CANALES (La televisión digital soñada), proyectos que además, comprometen en su ADN, procesos de apropiación social de conocimientos.
Enfermedad por esteatosis hepática, 2023 un año de cambios: revisión en la nomenclatura, diagnóstico y tratamiento
Authors: Fernández Castro Iván , Novo-Veleiro Ignacio , Martínez de Rituerto Santiago Tomé 
Published: May 2024

RESUMEN:
La enfermedad por esteatosis hepática es un problema de salud que afecta a casi un tercio de la población mundial. Hasta el año 2023 era conocida como hígado graso no alcohólico, pero esta nomenclatura se ha decidido cambiar ya que puede suponer un estigma para los pacientes y era confusa a la hora de reflejar los posibles agentes etiológicos en su desarrollo.
Los métodos diagnósticos a nuestro alcance, entre los que debemos destacar el FIB-4 y la elastografía controlada por vibración, se centran en identificar a los pacientes con una fibrosis significativa con el fin de evitar el desarrollo de una cirrosis.
Su tratamiento se basa en cambios de estilo de vida como son la pérdida de peso sostenida, la actividad de física regular, una dieta equilibrada y la abstinencia de consumo de alcohol. Medidas que se complementan con tratamientos farmacológicos aprobados para las patologías que se suelen asociar en estos pacientes, vitamina E, pioglitazonas, inhibidores de SGLT2, análogos de GLP-1 y la cirugía bariátrica.
Con esta revisión pretendemos destacar los importantes cambios en la terminología llevados a cabo, la importancia de algoritmos de diagnóstico temprano, el abordaje multidisciplinar como pilar del tratamiento y la esperanza de nuevas líneas terapéuticas contra este desafiante problema de salud.

ABSTRAC:
Steatosic liver disease is a prevalent health issue affecting nearly a third of the global population. Until 2023, it was known as nonalcoholic fatty liver disease (NAFLD), but this nomenclature has been altered due to potential stigmatization for patients and its lack of clarity in reflecting the possible etiological factors in its development.
FIB-4 and vibration-controlled elastography are diagnostic methods available to us, which focus on identifying patients with significant fibrosis to prevent cirrhosis development.
Lifestyle modifications, including sustained weight loss, regular physical activity, a balanced diet, and abstaining from alcohol consumption are the key to treatment. These measures are supplemented by pharmacological treatments approved for conditions commonly associated with these patients: vitamin E, pioglitazones, SGLT2 inhibitors, GLP-1 analogues, and bariatric surgery.
This review aims to underscore significant terminology changes, the importance of early diagnostic algorithms, the multidisciplinary approach as a cornerstone of treatment, and the hope for novel therapeutic avenues against this challenging health issue.
Mining as a Sustainable Development: Social License vs. State license
Authors: Salas Obed Vargas , Curo Helen Mayte Cayte , Salinas María de los Angeles Aquije , López Ricardo Enrique Grundy 
Published: May 2024

Objective: The purpose of this study is to investigate mining activity as a sustainable development, based on the social license and the state license, with the aim of systematizing literature on obtaining the license to operate.

Theoretical Framework: This topic presents the main concepts and theories that support the research. Thus, the Social License to Operate and social conflicts stand out, providing a solid basis for understanding the context of the research.

Method: The methodology includes the review of previous research indexed in the Scopus and Web of Science databases. To do this, search strings were applied, using the Boolean operators AND, OR and NOT and applying pre-established search and screening criteria.

Results and Discussion: The main finding of the research is that Social License to Operate must have effective communication between the community and the business sector, so that possible changes related to the needs of the interest groups involved are considered in the future.

Implications of the research: the practical and theoretical implications of this research are that the qualities of the Social License to Operate have the possibility of varying social relations as long as environmental issues are addressed by the private sector and by policies. public.

Originality/Value: It contributes to the literature by showing that the Social License to Operate is gaining importance in scientific research, so that researchers open academic debate.
Advertising as An Influencing Factor on Consumer Behavior
Authors: Farooq Samiya , Maqbool Adeel 
Published: May 2024

Objectives: The objective of this study is to examine the role of advertising as a management strategy in contemporary business environments. It aims to explore how advertising interacts with customers and influences both internal and external organizational processes and activities. Additionally, the study seeks to address misconceptions surrounding advertising's purpose and societal impact, particularly regarding its perceived manipulation of consumers for monetary gain.

Methods: This study employs a qualitative approach to investigate the role of advertising in modern business practices. It involves a comprehensive review of literature and existing research to analyze the relationship between advertising, consumer behavior, and organizational management strategies.

Results: The analysis reveals that advertising serves as a crucial management tool for businesses, facilitating interaction with customers and driving organizational processes. Contrary to misconceptions, advertising is not solely aimed at manipulating consumers for profit but also serves to fulfill customer needs for information about brands, services, and products. Additionally, the study finds that factors such as age, income, and satisfaction with promoted goods after purchase do not significantly influence the impact of advertisements on consumer purchasing decisions.

Conclusion: In conclusion, advertising plays a multifaceted role in contemporary business environments, serving as both a communication tool and a management strategy. While it is often misunderstood and criticized for its perceived manipulative nature, advertising remains a fundamental aspect of modern marketing practices. By understanding the complexities of advertising's influence on consumer behavior, businesses can develop more effective marketing strategies and better serve their customers' needs.
National Economic Stimulus Policy to Reduce Non-Performing Loan Risk on Msme Debtors Affected by Covid-19 Disturbing Banking Performance and National Financial System
Authors: Zubaedah Rahmi , Zarkasyi Wahyudin , Hilmi Indah Laily 
Published: May 2024

Purpose: This study aims to analyze the effectiveness of stimulus policies implemented by The Financial Services Authority (OJK) in response to the current pandemic, specifically in aiding MSME debtors impacted by Covid-19 and mitigating the occurrence of bad credit.

Method: The research adopts a normative approach combined with both statutory and empirical juridical methodologies to examine the implementation of stimulus policies by OJK, particularly focusing on the provisions outlined in POJK Number: 11/POJK.03/2020.

Results and conclusion: The findings reveal that the economic stimulus policy introduced by the government has the potential to assist MSME debtors adversely affected by Covid-19 and alleviate the burden of bad loans. The extension of credit restructuring until March 2022 provided by this policy is identified as a key factor in facilitating increased lending activities and fostering accelerated national economic growth.

Research implications: This study contributes to the understanding of the efficacy of stimulus measures in addressing economic challenges posed by the pandemic, particularly in the context of MSMEs. It underscores the importance of timely and targeted interventions in supporting vulnerable sectors and safeguarding financial stability.

Originality/value: By combining normative and empirical juridical approaches, this research offers a comprehensive analysis of the implementation of stimulus policies by OJK and their impact on MSME debtors. The identification of specific provisions, such as credit restructuring extensions, provides valuable insights for policymakers, financial regulators, and stakeholders involved in formulating effective economic recovery strategies.
Asbab Al-Wurud as an Approach to Understanding the Purpose of Hadith (Maqasid Al-Sunnah) in a Wasatiyyah and Balanced Way that is Practiced in Contemporary Society
Authors: Masruri Muhammad , Sahimi Mohd Shafiq , Karim Abdul , Ahmad Shakila binti 
Published: May 2024

Objective: The understanding and implementation of the Hadith, as the second main source in Islam, should align with the intended purpose and message delivered by the Hadith to its audience. To preserve the peace of humanity, one of these qualities involves being balanced, moderate, and not extreme. Currently, there are still a significant number of Muslims who excessively adhere to the Hadith of the Prophet, exhibit harsh behavior from a liberal perspective, or solely rely on logical reasoning.

Theoretical framework: This article seeks to elucidate the application of maqasid al-Sunnah in the interpretation of the Hadith of the Prophet SAW, employing the methodologies established by renowned scholars as well as the method of asbab al-wurud in a balanced and moderate manner.

Method: This article uses content analysis to examine discussions on the method of asbab al-wurud as an approach to maqasid al-sunnah. This method is used to interpret hadith in a comprehensive and balanced way.

Results and Discussion: Attaining equilibrium and unity in life is one of the primary objectives of the observance of the Hadith of the Prophet. To achieve this objective, it is necessary to comprehend the Nabawi Hadith in a straightforward and equitable manner, aligning with its intended purpose and objective. The understanding and interpretation of a hadith, as well as its transmission to the listener, can be obtained by consulting the scholarly opinions of the Salf al-Salih and considering the asbab al-Wurud.

Conclusion: The concept of maqasid al-sunnah, when understood through the lens of the ultimate hadith and the application of the method of asbab al-wurud, allows for a more comprehensive and balanced comprehension of a hadith. This approach ensures that the hadith is interpreted in a manner that is in line with the conditions of the current times and places, and is accepted by all Muslims. This strategy enables the effective management and regulation of extreme, excessively literal, and radical comprehension, resulting in the attainment of peace and well-being for all of humanity.
Contrast-induced encephalopathy with acute stroke symptomatic: a case report
Authors: Corona Andrea , Zehnder Joanna Meret , Kajdi-Schwab Marie-Elisabeth , Meyer Matthias , Caporale Christina Michaela , Sardo Salvatore , Porta Francesca Margherita 
Published: May 2024

Background:
Contrast-induced encephalopathy (CIE) is an infrequent complication of contrast media administration. It is usually transient but occasionally leads to permanent neurological deficits and death.

Case Presentation:
We report here a case of nonionic iodized CIE after an urgent coronary angiography, in a 62-year-old woman who developed symptoms of acute stroke. Although diagnostic challenge and under not specific but supportive therapy the symptoms resolved completely within 72 hours without further complications.

Conclusion:
CIE is a rare entity whose frequency is dependent on the increasing use of diagnostic/interventional procedures with contrast media. The exclusion of more common complications of such procedures should be prompt. The clinical scenario is challenging and should be considered, in particular in high-risk patients. The course is generally benign and requires supportive therapy.
A case report on Creutzfeldt-Jacob disease: early diagnosis through multidisciplinary lens
Authors: Parvin Hena , Dutta Anwesha , Hazra Subhrajit 
Published: May 2024

Background:
Creutzfeldt Jacob disease is a rapidly progressive neurodegenerative disorder, which is invariably fatal and results in death within 1 year of onset. The patient presents with a variety of non-specific neuropsychiatric symptoms, such as myoclonus, cerebellar symptoms, visual impairment, and behavioral abnormalities. The symptoms are rapidly progressive and cause early functional impairment in the patient.

Case Presentation:
In this report, we discussed a case of 49-year-old male presented with multiple neuropsychiatric symptoms. After a series of extensive diagnostic examinations and follow-up, the patient was diagnosed as having probable sporadic Creutzfeldt-Jakob disease based on 2018 Centres for Disease Control and Prevention criteria, with key findings of myoclonus, behavioral and cerebellar problems, visual abnormalities, abnormal hyperintensity signals on diffusion-weighted magnetic resonance imaging and characteristic electroencephalogram waves. CSF 14-3-3 protein was significantly high.

Conclusion:
Sporadic CJD is a rare and fatal rapidly progressive neurodegenerative disorder, that claims prompt and precise diagnosis to help clinicians distinguish it from potentially treatable neuropsychiatric disorders. This aspect elevates the significance of our report, as it aids not only the medical professionals but also the affected families. Early diagnosis enables the family to prepare for the disease course and appropriate management strategies.
PEMIDANAAN TERHADAP PELAKU TINDAK PIDANA PEMALSUAN KARTU KREDIT (STUDI PUTUSAN No.345/PID.SUS/2021/PNY-YK)
Authors: Setiawan R Andhika Prameswara , Ganarsih Yenti 
Published: May 2024

The crime of credit card forgery committed by Faisal Umar Firmansyah Bin Farid Firmansyah, namely the act of buying another person's CC (Credit Card) without the knowledge of the owner at a price of IDR 80,000 per credit card and purchasing 9 (nine) cellphones by checking whether registered in the KLARNA application and if registered and have a balance then the purchase will continue and if there is no balance in the KLARNA application then fill it in advance for every $1000 USA at a price of IDR 3,000,000 to IDR 5,000,000 .Research with Decision Study No.345/Pid.sus/2021/Pn.Yyk. and there is a formulation of the problem: 1. Is the court's decision against the convict's actions Credit Card Counterfeiting according to Ps. 32 paragraph (1) jo. Ps 48 paragraph (1) Law no. 19 of 2016 concerning Amendments to Law no. 11 of 2008 concerning Electronic Information and Transactions? This study uses a normative research type that is descriptive analytical, using literature or secondary data which consists of primary legal materials and secondary legal materials obtained from literature studies and analyzed qualitatively using deductive logic, as well as drawing conclusions. The conclusions from this study are that 1. The Court's decision given to the Defendant of the Crime of Credit Card Counterfeiting is not appropriate based on Article 32 paragraph (1) jo. Ps 48 paragraph (1) Law no. 19 of 2016 concerning Amendments to Law no. 11 of 2008 concerning Information and Electronic Transactions, and 2. Judge's Decision No. 345/Pid.Sus/2021/PN Yyk which imposes a criminal sanction of 6 (six) months in prison is not in accordance with the purpose of sentencing.
A combined cross-sectional analysis and case-control study evaluating tick-borne encephalitis vaccination coverage, disease and vaccine effectiveness in children and adolescents, Switzerland, 2005 to 2022
Authors: Zens Kyra D , Altpeter Ekkehardt , Wymann Monica N , Mack Annora , Baer Nora B , Haile Sarah R , Steffen Robert , Fehr Jan S , Lang Phung 
Published: May 2024

Background
Tick-borne encephalitis (TBE) is a severe, vaccine-preventable viral infection of the central nervous system. Symptoms are generally milder in children and adolescents than in adults, though severe disease does occur. A better understanding of the disease burden and duration of vaccine-mediated protection is important for vaccination recommendations.

Aim
To estimate TBE vaccination coverage, disease severity and vaccine effectiveness (VE) among individuals aged 0–17 years in Switzerland.

Methods
Vaccination coverage between 2005 and 2022 was estimated using the Swiss National Vaccination Coverage Survey (SNVCS), a nationwide, repeated cross-sectional study assessing vaccine uptake. Incidence and severity of TBE between 2005 and 2022 were determined using data from the Swiss disease surveillance system and VE was calculated using a case–control analysis, matching TBE cases with SNVCS controls.

Results
Over the study period, vaccination coverage increased substantially, from 4.8% (95% confidence interval (CI): 4.1–5.5%) to 50.1% (95% CI: 48.3–52.0%). Reported clinical symptoms in TBE cases were similar irrespective of age. Neurological involvement was less likely in incompletely (1–2 doses) and completely (≥ 3 doses) vaccinated cases compared with unvaccinated ones. For incomplete vaccination, VE was 66.2% (95% CI: 42.3–80.2), whereas VE for complete vaccination was 90.8% (95% CI: 87.7–96.4). Vaccine effectiveness remained high, 83.9% (95% CI: 69.0–91.7) up to 10 years since last vaccination.

Conclusions
Even children younger than 5 years can experience severe TBE. Incomplete and complete vaccination protect against neurological manifestations of the disease. Complete vaccination offers durable protection up to 10 years against TBE.
In Silico Study of Bioactive Compounds in Herba Sambiloto (Andrographis paniculata Burm. F. Nees) as HIV-1 Reverse Transcriptase Inhibitor
Authors: Prasetiyo Andri , Martati Titiek , Saputra Putri Windari 
Published: May 2024

A medicinal plant known as sambiloto (Andrographis paniculata Burm. F. Nees) contains certain active compounds that potentially are anti-HIV. However, it is not yet known which compounds are involved in inhibiting HIV activity. This study aimed to identify potentially active compounds from the sambiloto plant that could inhibit the HIV-1 reverse transcriptase enzyme using the in-silico method. In silico methods that will be carried out are internal validation, molecular docking, ADMET prediction, and molecular dynamics. The molecular docking results showed that the five best compounds have potential as anti-HIV drugs compared to efavirenz with the rerank score -152.119 until -125.177 kcal/mol. In contrast, the rerank score of the comparison ligand is -94.7639 kcal/mol. The ADMET prediction showed that the selected compounds have a good pharmacokinetics profile and are nontoxic. The molecular dynamic results showed that deoxy-11,12-didehydroandrographiside and andropraphiside are stable and have potential as anti-HIV drugs with average RMSD values of 1.88 and 2.02 Å while the comparison ligand is 1.67 Å.