bluuebunny/crossref_metadata_2025_split huggingface dataset:
A combinatorial approach to transitive extensions of generously unitransitive permutation groups
Authors: Klin M. H. , Mesner D. M. , Woldar A. J. 
Published: February 2010

AbstractMotivated by symmetric association schemes (which are known to approximate generously unitransitive group actions), we formulate combinatorial approximations to transitive extensions of generously unitransitive permutation groups. Specifically, the notions of compatible and coherent partitions are suggested and investigated in terms of the orbits of an ambient group (H, Ω) on the k‐subsets of Ω, k=2, 3, 4. We apply these ideas to investigate transitive extensions of the automorphism groups of the classical Johnson and Hamming schemes. In the latter case, we further provide algorithmic details and computer‐generated data for the particular series of Hamming schemes H(m, 3), m⩾2. Finally, our approach is compared to the concept of a symmetric association scheme on triples in the sense of Mesner and Bhattacharya. © 2010 Wiley Periodicals, Inc. J Combin Designs 18:369–391, 2010
Mutually disjoint designs and new 5‐designs derived from groups and codes
Authors: Araya Makoto , Harada Masaaki , Tonchev Vladimir D. , Wassermann Alfred 
Published: February 2010

AbstractThe article gives constructions of disjoint 5‐designs obtained from permutation groups and extremal self‐dual codes. Several new simple 5‐designs are found with parameters that were left open in the table of 5‐designs given in (G. B. Khosrovshahi and R. Laue, t‐Designs with t⩾3, in “Handbook of Combinatorial Designs”, 2nd edn, C. J. Colbourn and J. H. Dinitz (Editors), Chapman & Hall/CRC, Boca Raton, FL, 2007, pp. 79–101), namely, 5−(v, k, λ) designs with (v, k, λ)=(18, 8, 2m) (m=6, 9), (19, 9, 7m) (m=6, 9), (24, 9, 6m) (m=3, 4, 5), (25, 9, 30), (25, 10, 24m) (m=4, 5), (26, 10, 126), (30, 12, 440), (32, 6, 3m) (m=2, 3, 4), (33, 7, 84), and (36, 12, 45n) for 2⩽n⩽17. These results imply that a simple 5−(v, k, λ) design with (v, k)=(24, 9), (25, 9), (26, 10), (32, 6), or (33, 7) exists for all admissible values of λ. © 2010 Wiley Periodicals, Inc. J Combin Designs 18: 305–317, 2010
Reading, study, and discussion of the “great texts” of literature, philosophy, and politics as a complement to contemporary leadership education literature
Authors: Frank Shushok , Moore Scott H. 
Published: February 2010

AbstractIn his article, “Educational Research: The Hardest Science of All,” policy scholar David Berliner (2002) asserts that “no unpoetic description of the human condition can ever be complete” (p. 20). Berliner's words echo the epistemological and methodological climate of late 1970s and early 1980s social science research, a phase often characterized as the “literary turn.” In this historical moment, social science scholars turned to interdisciplinary sources, most notably literary theory and the humanities, for new means of addressing the ineffable, aesthetic aspects of human activity. This work and emphasis remains a prominent, growing genre within several fields, exemplified by widespread recognition of Margaret Wheatley's poetic approach to leadership inquiry and pedagogy (2009), frequent inclusion of aesthetic works in leading research journals (such as Qualitative Inquiry), and recent creation of arts‐ and humanities‐based educational research criteria for submissions to the American Educational Research Association's annual conference and sponsored journals.No field of inquiry better illustrates the need to understand human activity as “poetic” than leadership, which is perhaps the quintessential marker of social existence. Accordingly, in this symposium we wish to explore how such interdisciplinary approaches, specifically those grounded in the humanities, have manifested in leadership inquiry and pedagogy. It is our hope that this collection of essays will illustrate the breadth and depth of the field of leadership studies, as well as offer our readers new perspectives and inspiration in their own research and practice.
Reconciling self, servant leadership, and learning: The Journey to the East as locus for reflection and transformation
Authors: Meixner Cara 
Published: February 2010

AbstractIn his article, “Educational Research: The Hardest Science of All,” policy scholar David Berliner (2002) asserts that “no unpoetic description of the human condition can ever be complete” (p. 20). Berliner's words echo the epistemological and methodological climate of late 1970s and early 1980s social science research, a phase often characterized as the “literary turn.” In this historical moment, social science scholars turned to interdisciplinary sources, most notably literary theory and the humanities, for new means of addressing the ineffable, aesthetic aspects of human activity. This work and emphasis remains a prominent, growing genre within several fields, exemplified by widespread recognition of Margaret Wheatley's poetic approach to leadership inquiry and pedagogy (2009), frequent inclusion of aesthetic works in leading research journals (such as Qualitative Inquiry), and recent creation of arts‐ and humanities‐based educational research criteria for submissions to the American Educational Research Association's annual conference and sponsored journals.No field of inquiry better illustrates the need to understand human activity as “poetic” than leadership, which is perhaps the quintessential marker of social existence. Accordingly, in this symposium we wish to explore how such interdisciplinary approaches, specifically those grounded in the humanities, have manifested in leadership inquiry and pedagogy. It is our hope that this collection of essays will illustrate the breadth and depth of the field of leadership studies, as well as offer our readers new perspectives and inspiration in their own research and practice.
Teaching with music: An alternative pedagogy for leadership educators
Authors: Hall John L. 
Published: February 2010

AbstractIn his article, “Educational Research: The Hardest Science of All,” policy scholar David Berliner (2002) asserts that “no unpoetic description of the human condition can ever be complete” (p. 20). Berliner's words echo the epistemological and methodological climate of late 1970s and early 1980s social science research, a phase often characterized as the “literary turn.” In this historical moment, social science scholars turned to interdisciplinary sources, most notably literary theory and the humanities, for new means of addressing the ineffable, aesthetic aspects of human activity. This work and emphasis remains a prominent, growing genre within several fields, exemplified by widespread recognition of Margaret Wheatley's poetic approach to leadership inquiry and pedagogy (2009), frequent inclusion of aesthetic works in leading research journals (such as Qualitative Inquiry), and recent creation of arts‐ and humanities‐based educational research criteria for submissions to the American Educational Research Association's annual conference and sponsored journals.No field of inquiry better illustrates the need to understand human activity as “poetic” than leadership, which is perhaps the quintessential marker of social existence. Accordingly, in this symposium we wish to explore how such interdisciplinary approaches, specifically those grounded in the humanities, have manifested in leadership inquiry and pedagogy. It is our hope that this collection of essays will illustrate the breadth and depth of the field of leadership studies, as well as offer our readers new perspectives and inspiration in their own research and practice.
Tissue plasminogen activator and plasminogen are critical for osmotic homeostasis by regulating vasopressin secretion
Authors: Imamura Yuhki , Morita Shoko , Nakatani Yoshihiro , Okada Kiyotaka , Ueshima Shigeru , Matsuo Osamu , Miyata Seiji 
Published: February 2010

AbstractSystemic osmotic homeostasis is regulated mainly by neuroendocrine system of arginine‐vasopressin (AVP) in mammalians. In the present study, we demonstrated that the immunoreactivity of tissue plasminogen activator (tPA) was observed specifically at neurosecretory granules of AVP‐positive magnocellular terminals and that of plasminogen was seen at astrocytes in the neurohypophysis (NH). Both tPA and plasminogen knockout (KO) mice revealed higher plasma osmolarity upon water deprivation, a chronic osmotic stimulation, as compared with their wild‐type (WT) animals, indicating abnormal osmotic control in these KO mice. tPA KO mice but not plasminogen ones revealed lower ability in secreting AVP into the blood circulation upon an acute osmotic stimulation. Both tPA and plasminogen KO animals showed lower ability in secreting AVP into the blood circulation upon a chronic osmotic stimulation. The recombinant tPA was able to promote the release of AVP from isolated NH. Chronic osmotic stimulation decreased the laminin expression level of neurohypophysial microvessel in WT mice but not in plasminogen KO ones. We suggest that AVP secretion is critically regulated by tPA‐dependent facilitation of AVP release from terminals and plasminogen‐dependent increase of AVP permeability across microvessels possibly via laminin degradation. © 2010 Wiley‐Liss, Inc.
A mutation in the saposin C domain of the sphingolipid activator protein (Prosaposin) gene causes neurodegenerative disease in mice
Authors: Yoneshige Azusa , Suzuki Kinuko , Suzuki Kunihiko , Matsuda Junko 
Published: February 2010

AbstractSaposins A, B, C, and D are small amphiphatic glycoproteins that are encoded in tandem within a precursor protein (prosaposin, PSAP), and are required for in vivo degradation of sphingolipids. Humans with saposin C deficiency exhibit the clinical presentation of Gaucher‐like disease. We generated two types of saposin C mutant mice, one carrying a homozygous missense mutation (C384S) in the saposin C domain of prosaposin (Sap‐C−/−) and the other carrying the compound heterozygous mutation with a second null Psap allele (Psap−/C384S). During early life stages, both Sap‐C−/− and Psap−/C384S mice grew normally; however, they developed progressive motor and behavioral deficits after 3 months of age and the majority of affected mice could scarcely move by about 15 months. They showed no signs of hepatosplenomegaly throughout their lives. No accumulation of glucosylceramide and glucosylsphingosine was detected in the brain or liver of both Sap‐C−/− and Psap−/C384S mice. Neuropathological analyses revealed patterned loss of cerebellar Purkinje cells, widespread axonal spheroids filled with membrane‐derived concentric or lamellar electron‐dense bodies, and lipofuscin‐like deposition in the neurons. Soap‐bubble‐like inclusion bodies were detected in the trigeminal ganglion cells and the vascular endothelial cells. Compound heterozygous Psap−/C384S mice showed qualitatively identical but faster progression of the neurological phenotypes than Sap‐C−/− mice. These results suggest the in vivo role of saposin C in axonal membrane homeostasis, the disruption of which leads to neurodegeneration in lysosomal storage disease. © 2010 Wiley‐Liss, Inc.
Ionic mechanisms of action of prion protein fragment PrP(106–126) in rat basal forebrain neurons
Authors: Alier Kwai , Li Zongming , MacTavish David , Westaway David , Jhamandas Jack H. 
Published: February 2010

AbstractPrion diseases are neurodegenerative disorders that are characterized by the presence of the misfolded prion protein (PrP). Neurotoxicity in these diseases may result from prion‐induced modulation of ion channel function, changes in neuronal excitability, and consequent disruption of cellular homeostasis. We therefore examined PrP effects on a suite of potassium (K+) conductances that govern excitability of basal forebrain neurons. Our study examined the effects of a PrP fragment [PrP(106–126), 50 nM] on rat neurons using the patch clamp technique. In this paradigm, PrP(106–126) peptide, but not the “scrambled” sequence of PrP(106–126), evoked a reduction of whole‐cell outward currents in a voltage range between –30 and +30 mV. Reduction of whole‐cell outward currents was significantly attenuated in Ca2+‐free external media and also in the presence of iberiotoxin, a blocker of calcium‐activated potassium conductance. PrP(106–126) application also evoked a depression of the delayed rectifier (IK) and transient outward (IA) potassium currents. By using single cell RT‐PCR, we identified the presence of two neuronal chemical phenotypes, GABAergic and cholinergic, in cells from which we recorded. Furthermore, cholinergic and GABAergic neurons were shown to express Kv4.2 channels. Our data establish that the central region of PrP, defined by the PrP(106–126) peptide used at nanomolar concentrations, induces a reduction of specific K+ channel conductances in basal forebrain neurons. These findings suggest novel links between PrP signalling partners inferred from genetic experiments, K+ channels, and PrP‐mediated neurotoxicity. © 2010 Wiley‐Liss, Inc.
Antiapoptotic and antiautophagic effects of glial cell line‐derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats
Authors: Shang Jingwei , Deguchi Kentaro , Yamashita Toru , Ohta Yasuyuki , Zhang Hanzhe , Morimoto Nobutoshi , Liu Ning , Zhang Xuemei , Tian Fengfeng , Matsuura Tohru , Funakoshi Hiroshi , Nakamura Toshikazu , Abe Koji 
Published: February 2010

AbstractGlial cell line‐derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are strong neurotrophic factors, which function as antiapoptotic factors. However, the neuroprotective effect of GDNF and HGF in ameliorating ischemic brain injury via an antiautophagic effect has not been examined. Therefore, we investigated GDNF and HGF for changes of infarct size and antiapoptotic and antiautophagic effects after transient middle cerebral artery occlusion (tMCAO) in rats. For the estimation of ischemic brain injury, the infarct size was calculated at 24 hr after tMCAO by HE staining. Terminal deoxynucleotidyl transferase‐mediated dUTP‐biotin in situ nick end labeling (TUNEL) was performed for evaluating the antiapoptotic effect. Western blot analysis of microtubule‐associated protein 1 light chain 3 (LC3) and immunofluorescence analysis of LC3 and phosphorylated mTOR/Ser2448 (p‐mTOR) were performed for evaluating the antiautophagic effect. GDNF and HGF significantly reduced infarct size after cerebral ischemia. The amounts of LC3‐I plus LC3‐II (relative to β‐tubulin) were significantly increased after tMCAO, and GDNF and HGF significantly decreased them. GDNF and HGF significantly increased p‐mTOR‐positive cells. GDNF and HGF significantly decreased the numbers of TUNEL‐, LC3‐, and LC3/TUNEL double‐positive cells. LC3/TUNEL double‐positive cells accounted for about 34.3% of LC3 plus TUNEL‐positive cells. This study suggests that the protective effects of GDNF and HGF were greatly associated with not only the antiapoptotic but also the antiautophagic effects; maybe two types of cell death can occur in the same cell at the same time, and GDNF and HGF are capable of ameliorating these two pathways. © 2010 Wiley‐Liss, Inc.
Effect of phosphorus status of the soil on selenium availability
Authors: Eich‐Greatorex Susanne , Krogstad Tore , Sogn Trine A. 
Published: February 2010

AbstractDue to its importance for human and animal health, low bioavailability of selenium (Se) is of concern in large parts of the world. Among the factors determining Se availability is competition for binding sites by other anions. In order to evaluate the effect of different soil P status on Se availability from fertilizer, adsorption studies were conducted with soils ranging from low to very high available P as measured in ammonium lactate (P‐AL) and addition of Se as either selenate or selenite. Generally selenite, and to some extent also selenate, adsorption decreased with increasing P‐AL status of the soil. However, in a silt loam, the increase in P‐AL from 140 (high) to 210 mg P kg–1 (very high) did not result in a corresponding decrease in Se adsorption. Phosphorus saturation, on the other hand, was found to be lower in the sample that was very high in available P, suggesting that both the total amount of P on binding sites and the amount of plant‐available P influence Se availability. Selenate addition caused an increase in P availability, especially when added together with phosphate to a silt loam with very high P‐AL status.
Two‐beam multiplexed CARS based on a broadband oscillator
Authors: Furusawa Kentaro , Hayazawa Norihiko , Kawata Satoshi 
Published: February 2010

AbstractA two‐beam multiplexed coherent anti‐Stokes Raman scattering (CARS) microscopy setup is demonstrated by using a broadband (BB) Ti:sapphire oscillator without using any specialty fibres. A well‐defined spectral structure of the source leads to a delay‐sensitive CARS measurement in two‐colour CARS and also provides an efficient means of obtaining three‐colour CARS signals combined with the dispersion compensation of the BB pulse. Our result implies that the background suppression is limited by the onset of the spurious signals caused by the different CARS process, qualitatively differing from what is typically observed in the CARS microscopy. Copyright © 2010 John Wiley & Sons, Ltd.
Microwave‐assisted extraction followed by CE for determination of catechin and epicatechin in green tea
Authors: Li Zhongbo , Huang Danni , Tang Zhuxin , Deng Chunhui 
Published: February 2010

AbstractIn this work, for the first time, microwave‐assisted extraction (MAE) followed by CE was developed for the fast analysis of catechin and epicatechin in green tea. In the proposed method, catechin and epicatechin in green tea samples were rapidly extracted by MAE technique, and then analyzed by CE. The MAE conditions and the method's validation were studied. It is found that the extraction time of 1 min with 400 W microwave irradiation is enough to completely extract catechin and epicatechin in green tea sample, whereas the conventional ultrasonic extraction (USE) technique needs long extraction time of 60 min. The method validations were also studied in this work. The calibration curve shows good linearity in 0.01–3 mg/mL for catechin (R2=0.993), and 0.005–3 mg/mL for epicatechin (R2=0.996), respectively. The RSD values for catechin and epicatechin are 0.65 and 2.58%, respectively. This shows that the proposed method has good reproducibility. The proposed method has good recoveries, which are 118% for catechin and 120% for epicatechin. The proposed method was successfully applied to determination of the catechin and epicatechin in different green tea samples. The experiment results have demonstrated that the MAE following CE is a simple, fast and reliable method for the determination of catechin and epicatechin in green tea.
Single‐step extraction followed by LC for determination of (fluoro)quinolone drug residues in muscle, eggs, and milk
Authors: Cho Hee‐Jung , Yi Hee , Cho Soo Min , Lee Dong Goo , Cho Kyul , Abd El‐Aty A. M. , Shim Jae‐Han , Lee Soon‐Ho , Jeong Ji‐Yoon , Shin Ho‐Chul 
Published: February 2010

AbstractIn this study, a simplified method for the extraction and determination of seven fluoroquinolone residues (danofloxacin, difloxacin, enrofloxacin, marbofloxacin, orbifloxacin, ofloxacin, and sarafloxacin) and three quinolones (oxolinic acid, flumequine, and nalidixic acid), in porcine muscle, table eggs, and commercial whole milk, which required no cleanup step, was devised. This procedure involves the extraction of analytes from the samples via liquid‐phase extraction, and the subsequent quantitative determination was accomplished via LC‐fluorescence detection. Analyte separation was successfully conducted on an XBridge‐C18 column, with a linear gradient mobile phase composed of acetonitrile and 0.01 M oxalic acid buffer at pH=3.5. The one‐step liquid‐liquid extraction method evidenced good selectivity, precision (RSDs=0.26–15.07%), and recovery of the extractable analytes, ranging from 61.12 to 115.93% in matrices. The LOQs ranged from 0.3 to 25 μg/kg. A survey of ten samples purchased from local markets was conducted, and none of the samples harbored fluoroquinolone residues. This method is an improvement over existing methodologies, since no additional cleanup was necessary.
Frontal and associative visual areas related to visual hallucinations in dementia with Lewy bodies and Parkinson's disease with dementia
Authors: Sanchez‐Castaneda Cristina , Rene Ramon , Ramirez‐Ruiz Blanca , Campdelacreu Jaume , Gascon Jordi , Falcon Carles , Calopa Matilde , Jauma Serge , Juncadella Montserrat , Junque Carme 
Published: February 2010

AbstractVisual Hallucinations (VH) are among the core features of Dementia with Lewy Bodies (DLB), but are also very frequent in demented patients with Parkinson's Disease (PDD). The purpose of this study was to investigate the pattern of gray matter and cognitive impairment underlying VH in DLB and PDD. We applied voxel‐based morphometry and behavioral assessment to 12 clinically diagnosed DLB patients and 15 PDD patients. Subjects with VH showed greater gray matter loss than non‐hallucinators, specifically in the right inferior frontal gyrus (BA 45) in the DLB patients and in the left orbitofrontal lobe (BA 10) in the PDD patients. Comparing the two subgroups with VH, DLB patients had greater decrease of the bilateral premotor area (BA 6) than PDD patients. Furthermore, decreased volume in associative visual areas, namely left precuneus and inferior frontal lobe, correlated with VH in the DLB but not in PDD patients. VH were related to impaired verbal fluency, inhibitory control of attention and visuoperception in the DLB group and to visual memory in the PDD group. In conclusion, DLB and PDD patients with VH had more frontal gray matter atrophy than non‐hallucinators, the impairment being greater in the DLB group. The patterns of structural and functional correlations were different in both pathologies. © 2010 Movement Disorder Society
An early image of hemifacial spasm: Édouard Brissaud contribution
Authors: Colosimo Carlo , Berardelli Alfredo 
Published: February 2010

AbstractÉdouard Brissaud (1852–1909) was a French neuropsychiatrist of the Charcot school who provided in 1893 the first picture of a patient suffering from hemifacial spasm. Brissaud already suggested several possible etiologies for the involuntary movements of his patient, including the possibility of arterial malformations compressing the origin of the facial nerve. We also discuss the role of other early European authors (Schültze, Gowers, Babinski, and Negro) who contributed to the definition of hemifacial spasm in the late 19th and early 20th centuries. © 2010 Movement Disorder Society
Prediction of Microporous Aluminophosphate AlPO4‐5 Based on Resampling Using Partial Least Squares and Logistic Discrimination
Authors: Qi Miao , Lu Yinghua , Wang Jianzhong , Kong Jun 
Published: February 2010

AbstractIn this paper, Partial Least Squares (PLS) regression and Logistic Discrimination (LD) are employed to predict the formation of microporous aluminophosphate AlPO4‐5 based on the database of AlPO synthesis, which aims to provide a useful guidance to the rational synthesis of microporous materials as well as other inorganic crystalline materials. To deal with the problem of class imbalance, four guided resampling methods considering not only the between‐class imbalance but also the within‐class imbalance are proposed. Experimental results indicate that the presented methods are competent for predicting the formation of microporous aluminophosphate AlPO4‐5. Specially, compared with some existing resampling methods, our proposed resampling methods exhibit much better predictive results.