bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring “good days” in advanced cancer: Activities, behaviors, and quality of life.
Authors: Lazris David , Cheng Svea , Bartel Christianna , Durica Krina , Fedor Jennifer , Chen Leeann , Schenker Yael , Low Carissa A. 
Published: June 2024

12074 Background: Advancements in cancer treatments have contributed to people living longer with Stage IV cancer. People living with advanced cancer face significant and unique psychological challenges related to dynamic treatment schedules, fluctuating physical symptoms, and uncertainty regarding prognosis. Understanding what constitutes a “good day” may help patients, their family members, and clinicians to recognize and prioritize factors that improve quality of life. The goal of this project was to understand activities and behaviors that characterize a “good day” among people living with advanced cancer. Methods: We enrolled 20 patients with advanced cancer (M 63 years old, range 41-75; 65% female; 65% white and 35% black; mean 1.5 years since Stage IV diagnosis [range 9 days to 7.5 years]). Participants completed semi-structured interviews and two weeks of nightly diaries, using a 1-5 rating scale (1 = very bad, 5 = very good) to rate their daily quality of life and document various activities and experiences. We conducted t-tests to determine differences in “goodness” on days with and without different experiences along with a Pearson correlation between each patients’ mean goodness rating and Patient-Reported Outcomes Measurement Information System (PROMIS) scores. Results: Interviews revealed themes of "good days," including emphasizing control, normalcy, positive impact, and presence. Loss of control, uncertainty, disruptive symptoms, negative healthcare experiences, and unmet goals were more common on “bad days.” Nightly diaries revealed significant correlations between active engagement in social, hobby, club, religious, cooking, reading, and meditation activities and reporting a good day (all p values < .05). Mean diary goodness ratings correlated positively with Ability to Participate in Social Roles/Activities (r(19) = .54, p = .016) and inversely with Anxiety (r(19) =-.63, p = .004) and Depression (r(19) = -.53, p = .020) and was marginally inversely correlated with Fatigue (r(19) = -.44, p = .059) and Pain Interference (r(19) = -.46, p = .050). No significant correlations were observed with Physical Function (r(19) = .15, p = .544), Cognitive Function (r(19) = .36, p = .134), and Sleep Disturbance (r(19) = -.26, p = .286). Conclusions: Preliminary findings suggest that days on which individuals with advanced cancer are able to engage in activities that give them a sense of normalcy, control, self-identity, and connection to others are better than days without these activities. This is further supported by the positive correlation between goodness ratings and the ability to participate in social roles and activities. Understanding the individual’s values, perceived social roles, and priorities may help care teams support people with advanced cancer to optimize their quality of life and functioning and navigate treatment decisions.
Racial and ethnic differences in patient-reported provider communication among patients with cancer.
Authors: Swami Nishwant , Patel Tej A. , Dee Edward Christopher Christopher , Thom Bridgette , Chino Fumiko 
Published: June 2024

12102 Background: Patient-provider communication is essential for improving patient experience and understanding. Given significant care coordination in cancer treatment, effective communication is crucial to ensure timely care, optimal patient outcomes, and shared decision making. Improved patient-provider communication also provides opportunities to promote equitable cancer care. We used national survey data to assess racial/ethnic differences in perceptions of provider communication among patients with cancer. Methods: 2011-2021 biannual data from the US Medical Expenditure Panel Survey was used to select cancer survivors aged ≥18. Primary outcomes included how often patients reported their providers (1) treated them with respect, (2) listened carefully, (3) explained things in a way they understood, and (4) spent enough time. Survey-adjusted percentages with chi-square tests characterized differences in patient-reported communication by racial/ethnic group. Multivariable ordinal logistic regression (MVA) models adjusting for survey year, insurance status, income level, geography, sex, and age generated adjusted odds ratios (aORs) with 95% CI to examine associations of race/ethnicity and provider communication. Results: 5,085 patients representing 10,950,670 survivors met inclusion criteria. American Indian (AI) survivors reported the lowest rates of effective provider communication across all four domains (55%: always listened, 42%: always spent enough time, 58%: always showed respect, and 50%: always explained; p<.001), while non-Hispanic Black (NHB) patients reported the highest rates of effective communication in listening (72%), explaining (70%), respect (74%), and spending enough time (63%; p<.001). On MVA, NHB, non-Hispanic Asian (NHA), and Hispanic (HSP) patients were more likely to report feeling listened to (NHB: OR 1.54 95% CI 1.19-1.98; NHA: OR 1.87 95% CI 1.14-3.05; HSP: OR 1.39 95% CI 1.06-1.83) when compared to non-Hispanic White (NHW) patients. NHB and HSP patients reported feeling more respected (NHB: OR 1.40 95% CI 1.109-1.81; HSP: OR 1.39 95% CI 1.04-1.86) when compared to NHW patients. NHB patients were more likely to report that doctors explained well (OR: 1.31 95% CI 1.02-1.67). Conclusions: This national analysis finds that cancer survivors from historically (and presently) marginalized groups – including Black, Asian, and Hispanic patients - were more likely to perceive effective provider communication when compared to non-Hispanic White patients. Considering known disparities in cancer care access and outcomes, these results may reflect differing patient expectations of effective provider communication or the positive results of concerted efforts to improve provider communication to marginalized groups. Univariate analysis also revealed less effective communication for AI patients, suggesting potential unmet needs.
Investigating the mediating role of mental adjustment in the relationship between perceived stress and quality of life in patients with cancer.
Authors: Onyedibe Maria-Chidi Christiana , Chidebe Runcie C. W. 
Published: June 2024

12106 Background: Cancer patients undergo a multifaceted journey fraught with substantial psychological distress and coping hurdles, profoundly influencing their overall well-being. The intricate nexus between perceived stress and diminished Health-Related Quality of Life (HRQoL) in this population has garnered significant attention. However, the pivotal role played by mental adjustment to cancer (MAC) as a potential mediator in this intricate relationship remains inadequately explored. Given the paramount importance of understanding the psychological dynamics inherent to cancer care, our study sought to delve into the mediating influence exerted by MAC on the association between perceived stress and HRQoL among individuals grappling with cancer. Methods: The study enrolled 214 cancer patients (74 male, 140 female, mean age = 50.57, SD= 13.07) from a University Teaching Hospital in South-West Nigeria. Participants completed assessments utilizing the Impact of Event Scale, Mental Adjustment to Cancer, and Health-Related Quality of Life (measured by the Functional Assessment of Cancer Therapy–General). The study utilized a cross-sectional design, and data analysis was performed using mediation analysis with PROCESS procedures in SPSS. Results: Results indicated that perceived stress was associated with lower HRQoL (β = -.71, p < .001, CI, -1.02, -.39). Among the five dimensions of MAC, three sub-dimensions: helplessness (β = -.49, p < .05, CI, -.95, -.02), anxious occupation (β = -1.45, p < .05, CI, -1.92, -.96) and cognitive avoidance (β = 1.43, p < .001, CI, .61 – 2.25) were significantly associated with HRQoL. Mediation analysis showed that only two dimensions—helplessness and anxious preoccupation —mediated the relationship between cancer-related stress and HRQoL. The indirect effect for both helplessness (β = -.14, SE = .069, CI -.24, -.01) and anxious preoccupation (β = -.31, SE = .09, CI -.51, -.15) were significant. The findings indicate that stress related to cancer may lead to elevated levels of helplessness and anxious preoccupation, subsequently contributing to a decrease in Health-Related Quality of Life (HRQoL). Conclusions: This study provides valuable insights into the intricate relationship between perceived stress, mental adjustment to cancer, and HRQoL, offering implications for targeted interventions aimed at enhancing the well-being of individuals grappling with the challenges of cancer diagnosis and treatment. By tailoring interventions to address these nuanced dynamics, healthcare providers can foster improved overall well-being and adaptive capacities in individuals navigating the complexities of cancer care. Key words: Cancer patients, mental adjustment to cancer, perceived stress, health-related quality of life
Defective FGFR1 Signaling Disrupts Glucose Regulation: Evidence From Humans With FGFR1 Mutations
Authors: Stamou Maria I , Chiu Crystal J , Jadhav Shreya V , Lopes Vanessa Ferreira , Salnikov Kathryn B , Plummer Lacey , Lippincott Margaret F , Lee Hang , Seminara Stephanie B , Balasubramanian Ravikumar 
Published: June 2024

Abstract

Context
Activation of fibroblast growth factor receptor 1 (FGFR1) signaling improves the metabolic health of animals and humans, while inactivation leads to diabetes in mice. Direct human genetic evidence for the role of FGFR1 signaling in human metabolic health has not been fully established.

Objective
We hypothesized that individuals with naturally occurring FGFR1 variants (“experiments of nature”) will display glucose dysregulation.

Methods
Participants with rare FGFR1 variants and noncarrier controls. Using a recall-by-genotype approach, we examined the β-cell function and insulin sensitivity of 9 individuals with rare FGFR1 deleterious variants compared to 27 noncarrier controls, during a frequently sampled intravenous glucose tolerance test at the Reproductive Endocrine Unit and the Harvard Center for Reproductive Medicine, Massachusetts General Hospital. FGFR1-mutation carriers displayed higher β-cell function in the face of lower insulin sensitivity compared to controls.

Conclusion
These findings suggest that impaired FGFR1 signaling may contribute to an early insulin resistance phase of diabetes pathogenesis and support the candidacy of the FGFR1 signaling pathway as a therapeutic target for improving the human metabolic health.
A comparison of adult-child and spousal cancer caregivers’ participation in medical decisions
Authors: Fenton Anny T. H. R. , Ornstein Katherine A. , Kent Erin E. , Miller-Sonet Ellen , Wright Alexi A. , Dionne-Odom J. Nicholas 
Published: June 2024

Background
Family caregivers often play a key role in medical decision-making for patients with cancer. Adult-children account for nearly half of caregivers, but often have less experience with serious illness care and decision-making and face unique relational challenges as the patient’s child. Yet little research explores the potentially distinctive decision-making, involvement in decisions, and support needs of adult-child caregivers.

Methods
Analysis of survey data of U.S. cancer caregivers conducted by CancerCare® in 2021. Chi-square tests and multivariable regression models assessed whether adult-child and spousal caregivers differed on the type of medical decisions they participated in (e.g., treatment planning, medication management), who made the decision (e.g., caregiver or joint decision), and the resources that informed decisions (e.g., friends and family, education materials).

Results
Adult-children (N = 892) were less likely than spouses (N = 314) to participate in treatment planning (beta = -0.41; 95%CI = -0.81,-0.01), but more likely to be involved in decisions about whether to challenge medical authority (e.g., seeking alternative treatment, second opinion) (beta = 0.50; 95%CI = 0.22,0.78). Compared to spouses, adult-children made joint decisions with patients less often (-13.2-percentage points; 95%CI = -19.64,-6.67) and acted as primary decision-maker more frequently (5.60-percentage points; 95%CI = 0.01,10.43). More adult-children than spouses sought help and information regarding decisions from the oncology team (8.42-percentage points; 95%CI = 1.98,14.87) and friends and family (7.91-percentage points; 95%CI = 1.34,14.48).

Conclusions
How cancer caregivers and patients are related to each other shapes caregivers’ medical decision-making. Adult-children’s and spouses’ probabilities of participating in and influencing decisions differed for certain types of decisions while adult-children were more likely to seek information and social support regarding decisions. These findings highlight the importance of the patient’s and caregiver’s relationship type in medical decision-making, suggesting that decision support programs may be more effective if they tailor programs by relationship type.
How breaking a sweat affects mood: The mediating role of self-efficacy between physical exercise and emotion regulation ability
Authors: Mu Fan-zheng , Liu Jun , Lou Hu , Zhu Wei-dong , Wang Zhen-cheng , Li Bo 
Published: June 2024

Objective
This study investigates the association between physical exercise and emotion regulation abilities among college students, introducing self-efficacy as a mediating variable to analyze the pathway mechanism through which physical exercise affects emotion regulation abilities.

Methods
A cross-sectional study design was employed, utilizing a stratified random sampling method to survey three colleges in Jiangsu Province, China. Physical Activity Rating Scale, Physical Activity Self-efficacy Scale, and Emotional Intelligence Scale were used to measure the college student population. Regression analysis and mediation tests assessed whether self-efficacy mediates the relationship between physical exercise and college students’ emotion regulation abilities. A total of 5,430 valid questionnaires were collected.

Results
The distribution of college students’ physical activities was 77.0% for low, 13.1% for medium, and 9.3% for high levels. Physical activities were significantly and positively correlated with self-efficacy and emotional management abilities (r = 0.298,0.105;P<0.01), and self-efficacy was significantly and positively correlated with emotional management abilities (r = 0.322, P<0.01). Situational motivation and subjective support under self-efficacy were 0.08 and 0.255, respectively, and the adjusted R2 was 0.107. Self-efficacy played a fully mediating role between physical activities and emotional management abilities, with a total effect value of 0.032. The values of the direct and indirect effects were 0.003 and 0.029, accounting for 8.95% and 90.74% of the total effect, respectively.

Conclusion
The physical exercise behavior of college students is primarily characterized by low intensity. Physical exercise among college students can positively predict their ability to regulate emotions. Self-efficacy fully mediates the relationship between physical exercise and emotion regulation ability among college students. College students can indirectly influence their ability to regulate emotions through physical exercise and self-efficacy.
Assessment of patient perceptions of counselling on oral antineoplastic agents by a dedicated cancer services pharmacist in an outpatient cancer clinic
Authors: McNabb Lorna , Metrot Eva , Ferrington Micaela , Sunderland Bruce , Parsons Richard , Copeland Tandy-Sue , Corscadden Siobhan , Tong Selina , Czarniak Petra 
Published: June 2024

Background
Oral antineoplastic agents have caused a paradigm shift in cancer treatment, however, they produce many unique challenges. Although oral antineoplastics can have complex administration regimes, low adherence rates and high possibilities of drug-drug interactions, they are administered unsupervised at home. Cancer services pharmacists have the required skillsets to improve patient outcomes associated with oral antineoplastic treatment by increasing patient health literacy, improving concordance and optimising administration protocols.

Aim
To evaluate patients’ perceptions, experiences and overall satisfaction with dedicated clinical pharmacist consultations in patients treated with oral antineoplastic agents at a major public hospital.

Method
In this retrospective cross-sectional study at a quaternary hospital in Western Australia, data were collected by a paper questionnaire (mailed in March 2022) to a random sample of 191 patients initiated on oral antineoplastic drugs between January 2021 and February 2022. Demographics, prescribed antineoplastic drug/s, cancer type data were collected including using 5-point Likert scale questions assess patients’ overall satisfaction with the clinical pharmacist consultations.

Results
The questionnaire response rate was 27.7% (52/188) (mean age 63.2 years; 57.5% female). Most patients (42/52; 80.8%) were satisfied with pharmacist consultations, trusted the pharmacist’s advice (45/52; 86.5%), considered that the pharmacist improved their understanding of how to manage side effects (43/52; 82.7%) and they provided an important service in outpatient care (45/52; 86.5%).

Conclusion
Overall, patients reported positive perceptions, experiences, and satisfaction with the cancer services pharmacist counselling services during their oral antineoplastic treatment.
Improving quality and patient safety in surgical care through standardisation and harmonisation of perioperative care (SAFEST project): A research protocol for a mixed methods study
Authors: Valli Claudia , Schäfer Willemijn L. A. , Bañeres Joaquim , Groene Oliver , Arnal-Velasco Daniel , Leite Andreia , Suñol Rosa , Ballester Marta , Gibert Guilera Marc , Wagner Cordula , Calsbeek Hiske , Emond Yvette , J. Heideveld-Chevalking Anita , Kristensen Kaja , Huibertina Davida van Tuyl Lilian , Põlluste Kaja , Weynants Cathy , Garel Pascal , Sousa Paulo , Talving Peep , Marx David , Žaludek Adam , Romero Eva , Rodríguez Anna , Orrego Carola ,   for the SAFEST consortium
Published: June 2024

Introduction
Adverse events in health care affect 8% to 12% of patients admitted to hospitals in the European Union (EU), with surgical adverse events being the most common types reported.

Aim
SAFEST project aims to enhance perioperative care quality and patient safety by establishing and implementing widely supported evidence-based perioperative patient safety practices to reduce surgical adverse events.

Methods
We will conduct a mixed-methods hybrid type III implementation study supporting the development and adoption of evidence-based practices through a Quality Improvement Learning Collaborative (QILC) in co-creation with stakeholders. The project will be conducted in 10 hospitals and related healthcare facilities of 5 European countries. We will assess the level of adherence to the standardised practices, as well as surgical complications incidence, patient-reported outcomes, contextual factors influencing the implementation of the patient safety practices, and sustainability. The project will consist of six components: 1) Development of patient safety standardised practices in perioperative care; 2) Guided self-evaluation of the standardised practices; 3) Identification of priorities and actions plans; 4) Implementation of a QILC strategy; 5) Evaluation of the strategy effectiveness; 6) Patient empowerment for patient safety. Sustainability of the project will be ensured by systematic assessment of sustainability factors and business plans. Towards the end of the project, a call for participation will be launched to allow other hospitals to conduct the self-evaluation of the standardized practices.

Discussion
The SAFEST project will promote patient safety standardized practices in the continuum of care for adult patients undergoing surgery. This project will result in a broad implementation of evidence-based practices for perioperative care, spanning from the care provided before hospital admission to post-operative recovery at home or outpatient facilities. Different implementation challenges will be faced in the application of the evidence-based practices, which will be mitigated by developing context-specific implementation strategies. Results will be disseminated in peer-reviewed publications and will be available in an online platform.
Journalism Practice and Critical Reflexivity, Bonita Mason (2023)
Authors: Glitsos Laura 
Published: June 2024

Review of: Journalism Practice and Critical Reflexivity, Bonita Mason (2023)
New York: Routledge, 226 pp.,
ISBN 978-1-13860-303-5, h/bk, AUD 218.40
ISBN 978-0-42946-922-0, e-book, AUD 73.99
Happiness in Journalism, Valérie Bélair-Gagnon, Avery E. Holton, Mark Deuze and Claudia Mellado (eds) (2023)
Authors: Lyall Kimina 
Published: June 2024

Review of: Happiness in Journalism, Valérie Bélair-Gagnon, Avery E. Holton, Mark Deuze and Claudia Mellado (eds) (2023)
London: Routledge, 216 pp.,
ISBN 978-1-03242-855-0, h/bk, AUD 273
ISBN 978-1-03242-854-3, p/bk, AUD 79.99
ISBN 978-1-00336-459-7, e-book, AUD 62.09
Taliesin West, 1972
Authors: Van Assche Pierre 
Published: June 2024

Résumé. Au cours d’un road trip aux États-Unis en 1972, la découverte fortuite et la visite d’un lieu mythique de l’histoire de l’architecture – la résidence et l’atelier d’hiver de Frank Lloyd Wright en Arizona – avec la rencontre étrange des deux personnages les plus proches du plus grand des architectes américains, décédé 13 ans plus tôt. Une anecdote singulière vécue comme un coup du destin dans le chef de l’auteur, jeune architecte fraîchement diplômé.
Abstract. During a road trip to the United States in 1972, the chance discovery and visit of a mythical place in the history of architecture – Frank Lloyd Wright's residence and winter studio in Arizona – with the strange meeting of the two characters closest to the greatest of American architects, who died 13 years earlier. A singular anecdote experienced as a stroke of fate by the author, a young, freshly graduated architect.
Boundedness, existence and uniqueness results for coupled gradient dependent elliptic systems with nonlinear boundary condition
Authors: Frisch Michal Maria , Winkert Patrick 
Published: June 2024

Abstract
In this paper, we study coupled elliptic systems with gradient dependent right-hand sides and nonlinear boundary conditions, where the left-hand sides are driven by so-called double phase operators. By applying a surjectivity result for pseudomonotone operators along with an equivalent norm in the function space, we prove that the system has at least one nontrivial solution under very general assumptions on the data. Under slightly stronger conditions, we are also able to show that this solution is unique. As a result of independent interest, we further prove the boundedness of solutions to such elliptic systems by employing Moser’s iteration scheme.