bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphological and molecular characterization of Eimeria haematopusi n. sp. (Apicomplexa: Eimeriidae) in an Australian Pied Oystercatcher (Haematopus longirostris) (Aves: Charadriiformes)
Authors: Austen Jill M. , Brice Belinda , Liu Dandan , Gao Huimin , Berto Bruno P. , Zahedi Alireza , Elloit Aileen , Yang Rongchang 
Published: May 2024

AbstractA novel Eimeria Schneider, 1875 species is described from an Australian pied oystercatcher Haematopus longirostris Vieillot, in Western Australia. The pied oystercatcher was admitted to the Kanyana Wildlife Rehabilitation Centre (KWRC), Perth, Western Australia in a poor body condition, abrasion to its right hock and signs of partial delamination to its lower beak. Investigation into potential medical causes resulted in a faecal sample being collected and screened for gastrointestinal parasites. Unsporulated coccidian oocysts were initially observed in the faeces and identified as Eimeria upon sporulation. The sporulated oocysts (n = 20) are ellipsoidal, 20–21 × 12–13 μm in shape and have thick bi-layered walls which are c.2/3 of the total thickness. Micropyle is present, robust and protruding, and occasionally has a rounded polar body attached to the micropyle. Within the oocyst, a residuum, in addition, two to five polar granules are present. There are four ellipsoidal sporocysts 9–11 × 5–6 μm with flattened to half-moon shaped Stieda bodies. Sub-Stieda body and para-Stieda body are absent. The sporocysts contain sporocyst residuums composed of a few spherules scattered among the sporozoites. Within the sporozoites, anterior and posterior refractile bodies are present, but the nucleus is indiscernible. To further characterise the novel Eimeria species from H. longirostris, molecular analysis was conducted at the 18S ribosomal RNA locus, using PCR amplification and cloning. Two cloned sequences from the novel Eimeria were compared with those from other Eimeria spp. with the highest genetic similarity of 97.6% and 97.2% from Clone 1 and 2, respectively with Eimeria reichenowi (AB544308) from a hooded crane (Grus monacha Temminck) in Japan. Both sequences grouped in a clade with the Eimeria spp. isolated from wetland birds, which include Eimeria paludosa (KJ767187) from a dusky moorhen (Gallinula tenebrosa Gould) in Western Australia, Eimeria reichenowi (AB544308) and Eimeria gruis (AB544336) both from hooded cranes. Based on the morphological and molecular data, this Eimeria sp. is a new species of coccidian parasite and is named Eimeria haematopusin. sp. after its host H. longirostris.
Outcomes of para-sacral transcutaneous electric nerve stimulation in treatment of primary and refractory overactive bladder among children
Authors: Gomaa Moetaz Dahshan , AbdAllah Hany Aref , Ismail Iman Yehia , Wasfy Isaac Samir , Sherief Mahmoud Hegazy 
Published: May 2024

Abstract
Background
Overactive bladder (OAB) is the most prevalent lower urinary tract dysfunction among children. Refractory OAB lacks response to the first line treatments, including anticholinergic, and it is a major clinical challenge. This study aims to compare the efficacy of para-sacral transcutaneous electric nerve stimulation (PS-TENS) in the treatment of primary and refractory OAB among children.

Methods
A prospective, randomized clinical study included 64 children aged 5–12 years with OAB divided equally into two groups: group (1) included 32 children with treatment-naive OAB, while group (2) included 32 children with refractory OAB who failed complete course of anticholinergics. Both groups received PS-TENS three times weekly for 12 weeks. Detailed medical history, voiding diary, ultrasound, and uroflowmetry with EMG were performed at baseline and after 12 weeks of treatment. Filling cystometry was performed for children with refractory OAB before and after PS-TENS.

Results
After the end of treatment the number of children with urge incontinence decreased significantly among the two groups: from 25 to 13 and 27 to 15 for the primary and refractory groups, respectively. Micturition frequency per 24 h decreased significantly among children with primary OAB. Bladder capacity increased significantly and the resting detrusor pressure decreased significantly among children with refractory OAB.

Conclusions
PS-TENS is an effective and safe treatment option for children with OAB. The magnitude of improvement is higher among children with primary as compared to refractory OAB.
Serum vitamin D concentrations and sleep disorders: insights from NHANES 2011–2016 and Mendelian Randomization analysis
Authors: Jiang Junjie , Tan Hanyu , Xia Zhongfang , Li Jun , Zhou Shuang , Huang Tao 
Published: May 2024

Abstract
Objective
This investigation seeks to examine the association between serum vitamin D concentrations and the prevalence of sleep disorders, additionally elucidating the causal relationship via Mendelian Randomization (MR) analysis.

Materials and methods
This research employed data from the National Health and Nutrition Examination Survey (NHANES) 2011–2016, focusing on adults aged 20–50 years reporting sleep disorders. The research encompassed 4913 American adults. Weighted multivariable logistic regression models and cubic spline analyses were utilized to evaluate the association between serum vitamin D concentrations and the incidence of sleep disorders. Additionally, a two-sample Mendelian Randomization analysis was performed to evaluate the potential causal link between serum vitamin D concentrations and the risk of sleep disorders.

Results
Within the 2011–2016 NHANES cohort of the U.S. population, a notable inverse association was detected between serum vitamin D concentrations and sleep disorders (β =  − 3.81, 95% CI: − 6.10 to − 1.52, p = 0.003). After multivariate adjustments, a higher incidence of sleep disorders was associated with lower vitamin D Concentrations (OR 1.52, 95% CI 1.10–2.10, trend p = 0.014). Restricted cubic spline regression analysis indicated a linear association between serum vitamin D concentrations and sleep disorders(non-linearity p > 0.05). Lastly, the two-sample MR analysis yielded evidence supporting a potential causal connection between serum vitamin D concentrations and sleep disorders, with each unit increase in genetically predicted serum vitamin D reducing the odds ratio to 0.78 (95% CI 0.61–0.99, p = 0.044).

Conclusions
These results imply that lower vitamin D concentrations in the population might correlate with a heightened risk of sleep disorders, suggesting the importance of considering vitamin D supplementation when treating sleep disorders.
Area-Level Social Vulnerability and Severe COVID-19: A Case–Control Study Using Electronic Health Records from Multiple Health Systems in the Southeastern Pennsylvania Region
Authors: Mullachery Pricila H. , Bilal Usama , Li Ran , McClure Leslie A. 
Published: May 2024

AbstractKnowledge about neighborhood characteristics that predict disease burden can be used to guide equity-based public health interventions or targeted social services. We used a case-control design to examine the association between area-level social vulnerability and severe COVID-19 using electronic health records (EHR) from a regional health information hub in the greater Philadelphia region. Severe COVID-19 cases (n = 15,464 unique patients) were defined as those with an inpatient admission and a diagnosis of COVID-19 in 2020. Controls (n = 78,600; 5:1 control-case ratio) were a random sample of individuals who did not have a COVID-19 diagnosis from the same geographic area. Retrospective data on comorbidities and demographic variables were extracted from EHR and linked to area-level social vulnerability index (SVI) data using ZIP codes. Models adjusted for different sets of covariates showed incidence rate ratios (IRR) ranging from 1.15 (95% CI, 1.13–1.17) in the model adjusted for individual-level age, sex, and marital status to 1.09 (95% CI, 1.08–1.11) in the fully adjusted model, which included individual-level comorbidities and race/ethnicity. The fully adjusted model indicates that a 10% higher area-level SVI was associated with a 9% higher risk of severe COVID-19. Individuals in neighborhoods with high social vulnerability were more likely to have severe COVID-19 after accounting for comorbidities and demographic characteristics. Our findings support initiatives incorporating neighborhood-level social determinants of health when planning interventions and allocating resources to mitigate epidemic respiratory diseases, including other coronavirus or influenza viruses.
Manufacturing of High Purity Cr2AlC MAX Phase Material and Its Characterization
Authors: Desai Vyom , Shrivastava Aroh , Zala Arunsinh B. , Parekh Tejas , Gupta Surojit , Jamnapara N. I. 
Published: May 2024

AbstractPresent study discusses about a technique for producing high-purity Cr2AlC MAX phase materials and gaining insight into their thermal behavior for high-temperature applications. The research conducted involved synthesizing a pure layered ternary carbide Cr2AlC MAX phase material by mixing powders of Chromium, Aluminum, and Carbon and then subjecting them to two-step pressureless sintering process in argon atmosphere. First step involves the annealing of ball-milled mixture at 750 °C for 2 h followed by the second step in which the annealed mixture is subjected to heat-treatment at 1350 °C for 2 h. Analysis using XRD and Raman techniques revealed that the synthesized product consists of Cr2AlC phase, without any impurities. SEM studies confirmed that the Cr2AlC had a layered topography, while EPMA analysis indicated that the atomic percentage of Cr, Al, and C was consistent with the XRD phase analysis. XPS investigations confirmed the presence of Cr-C bonds representing Mn+1Xn of the MAX phase material. TG-DSC results showed an approximately 2% increase in weight. The Cr2AlC phase exhibited an endothermic pattern below 725 °C, an exothermic pattern above it, and did not decompose up to 1400 °C in vacuum environment. High-temperature XRD analysis at various temperatures also confirmed no formation of Al2O3 or CrO impurity compounds.
Developing national cancer survivorship standards to inform quality of care in the United States using a consensus approach
Authors: Mollica Michelle A. , McWhirter Gina , Tonorezos Emily , Fenderson Joshua , Freyer David R. , Jefford Michael , Luevano Christopher J. , Mullett Timothy , Nasso Shelley Fuld , Schilling Ethan , Passero Vida Almario ,   the National Cancer Survivorship Standards Subject Matter Expert Group, Alfano Catherine , Belin Precilla , Blaes Anne , Cavanagh Hillary , Francis Lanie , Freyer David R. , Friedman Danielle , Nasso Shelley Fuld , Ganz Patricia , He Min , Honig Batsheva , Hudson Shawna , Jacobs Linda , Jefford Michael , Keating Nancy , Kirchoff Anne , Kirschner Michelle , Kline Ron , MacIntyre Jessica , Maher Molly , Mayer Deborah , Merrill Janette , Mullett Timothy , Nekhlyudov Larissa , Penedo Frank , Pergolotti Mackenzi , Roth Michael , Sanft Tara , Schatz Alyssa , Schilling Ethan , Schmitz Kathryn , Schwartz Lisa , Tonorezos Emily 
Published: May 2024

Abstract
Purpose
To develop United States (US) standards for survivorship care that informs (1) essential health system policy and process components and (2) evaluation of the quality of survivorship care.

Methods
The National Cancer Institute and the Department of Veterans Affairs led a review to identify indicators of quality cancer survivorship care in the domains of health system policy, process, and evaluation/assessment. A series of three virtual consensus meetings with survivorship care and research experts and advocates was conducted to rate the importance of the indicators and refine the top indicators. The final set of standards was developed, including ten indicators in each domain.

Results
Prioritized items were survivor-focused, including processes to both assess and manage physical, psychological, and social issues, and evaluation of patient outcomes and experiences. Specific indicators focused on developing a business model for sustaining survivorship care and collecting relevant business metrics (e.g., healthcare utilization, downstream revenue) to show value of survivorship care to health systems.

Conclusions
The National Standards for Cancer Survivorship Care can be used by health systems to guide development of new survivorship care programs or services or to assess alignment and enhance services in existing survivorship programs. Given the variety of settings providing care to survivors, it is necessary for health systems to adapt these standards based on factors including age-specific needs, cancer types, treatments received, and health system resources.

Implications for Cancer Survivors
With over 18 million cancer survivors in the United States, many of whom experience varied symptoms and unmet needs, it is essential for health systems to have a comprehensive strategy to provide ongoing care. The US National Standards for Survivorship Care should serve as a blueprint for what survivors and their families can anticipate after a cancer diagnosis to address their needs.
Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review
Authors: De Felice Elisabetta L.T. , Toti Gabriel F. , Gatti Beatrice , Gualtieri Renato , Camozzi Pietro , Lava Sebastiano A.G. , Milani Gregorio P. , Treglia Giorgio , Vanoni Federica , Bianchetti Mario G. , Bernasconi Gianmaria F. , Terziroli Beretta Piccoli Benedetta , Lavagno Camilla 
Published: May 2024

AbstractAn acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since case reports cannot be employed to draw inferences about the relationships between immunoglobulin therapy and meningitis, we conducted a systematic review and meta-analysis of the literature. Eligible were cases, case series, and pharmacovigilance studies. We found 71 individually documented cases (36 individuals ≤ 18 years of age) of meningitis. Ninety percent of cases presented ≤ 3 days after initiating immunoglobulin therapy and recovered within ≤ 7 days (with a shorter disease duration in children: ≤ 3 days in 29 (94%) cases). In 22 (31%) instances, the authors noted a link between the onset of meningitis and a rapid intravenous infusion of immunoglobulins. Cerebrospinal fluid analysis revealed a predominantly neutrophilic (N = 46, 66%) pleocytosis. Recurrences after re-exposure were observed in eight (N = 11%) patients. Eight case series addressed the prevalence of meningitis in 4089 patients treated with immunoglobulins. A pooled prevalence of 0.6% was noted. Finally, pharmacovigilance data revealed that meningitis temporally associated with intravenous immunoglobulin therapy occurred with at least five different products. In conclusion, intravenous immunoglobulin may cause an acute aseptic meningitis. The clinical features remit rapidly after discontinuing the medication.
Diagnostic Value of Single LH and LH/FSH Ratio at 60-minute after GnRHa Stimulation Test for Central Precocious Puberty
Authors: Wang Qingling , Wu Dan , Zeng Qian , Ban Chuanwei , Wang Ling , Lv Xin 
Published: May 2024

Abstract
Objectives
To evaluate the diagnostic value of luteinizing hormone (LH) and LH/follicle stimulating hormone (FSH) ratio at 60 min after gonadotropin-releasing hormone analogs (GnRHa) stimulation test for central precocious puberty (CPP) in girls.

Methods
Two hundred and fifty-seven girls, aged 3 to 7.5 y, suspected of precocious puberty at authors’ hospital from April 2020 through November 2023 were enrolled in the study. The blood was taken at 0, 30, 60 min after GnRHa stimulation test, and LH and LH/FSH were detected by chemiluminescence assay. The diagnostic efficacy was analysed by Mann–Whitney U test, spearman’s correlation analysis and receiver operating characteristic (ROC) analysis. The proportion of obesity was analysed by Chi-square test.

Results
LH and LH/FSH at different times were statistically significantly different (P <0.05) between the CPP and non-CPP groups. Spearman’s correlation analysis showed that the level of LH and LH/FSH at 60 min had the strongest consistency with the peak of LH (r = 0.9988, P <0.001) and LH/FSH (r = 0.9981, P <0.001). ROC curve analysis showed that the area under the ROC curves at 60 min of LH and LH/FSH were 0.975 and 0.997 with a cut-off value of 5.70 IU/L and 0.609, respectively.

Conclusions
The peak of LH and LH/FSH in the diagnosis of CPP can be determined by LH and LH/FSH at 60 min after the triptorelin acetate is injected. This will reduce the number of blood draws required compared with the traditional stimulation test, which is more effective and acceptable for children.
Existence of Solutions for p(x)-Laplacian Elliptic BVPs on a Variable Sobolev Space Via Fixed Point Theorems
Authors: Ayadi Souad , Alzabut Jehad , Afshari Hojjat , Sahlan Monireh Nosrati 
Published: May 2024

AbstractIn this paper, we prove some existence theorems for elliptic boundary value problems within the p(x)-Laplacian on a variable Sobolev space. For this purpose, the main problem is transformed into a fixed point problem and then fixed point arguments such as Schaefer’s and Schauder’s theorems are used. Our approach involves fewer stringent assumptions on the nonlinearity function than the prior findings. An interesting example is presented to examine the validity of the theoretical findings.
Feature-based deformation for flow visualization
Authors: Straub Alexander , Sadlo Filip , Ertl Thomas 
Published: May 2024

AbstractWe present an approach that supports the analysis of flow dynamics in the neighborhood of curved line-type features, such as vortex core lines, attachment lines, and trajectories. We achieve this with continuous deformation to the flow field to straighten such features. This provides “deformed frames of reference”, within which qualitative flow dynamics are better observable with respect to the feature. Our approach operates at interactive rates on graphics hardware, and supports exploration of large and complex datasets by continuously navigating the additional degree of freedom of deformation. We demonstrate the properties and the utility of our approach using synthetic and simulated flow fields, with a focus on the application to vortex core lines.
Graphical abstract
Spatiotemporal distribution of mangrove along the Egyptian Red Sea coast and analysis of hydrological impact on growth patterns
Authors: Sewilam H. , Hassan B. T. , Khalil B. S. 
Published: May 2024

AbstractThis study presents an in-depth spatiotemporal analysis of mangrove ecosystems along Egypt’s Red Sea coast, utilizing satellite imagery and GIS to examine changes from 2003 to 2022. We evaluate the effects of hydrological factors, specifically rainfall and runoff -presented by Stream Power Index-, on mangrove growth patterns. Results indicate a significant increase in mangrove areas, with a notable annual growth rate, despite a reduction in a specific region. This research highlights the integral role of catchment area runoff (R2 = 0.735, R = 0.857, P-value = 0.003 < 0.05, CV = 70.26%), rather than direct rainfall, in mangrove expansion, contributing to the understanding of mangrove resilience and informing sustainable coastal management strategies. The study bridges a significant research gap by mapping decadal mangrove changes, offering insights into the dynamics affecting these crucial ecosystems.
Innovative engine test bench set-up for testing of exhaust gas aftertreatment and detailed gas species analysis for CNG-SI-operation
Authors: Tomin Sebastian , Keller Kevin , Wagner Uwe , Lott Patrick , Koch Thomas , Deutschmann Olaf 
Published: May 2024

AbstractFor an efficient reduction of methane slip, a precise understanding of exhaust gas after treatment under real conditions is essential. Since it is not possible to produce catalytic converters in near-series geometry on a laboratory scale, it is necessary to resort to significantly smaller sample catalysts. Therefore, an engine test bench was designed to ensure real operating conditions for such samples with the help of space velocity and temperature control. A comparison between the actual and reference values of the space velocity results in a small deviation of 0.1% on average. Furthermore, the pressure conditions at the catalyst have been measured showing a propagation of pressure oscillations from the engine outlet which in combination with the space velocity regulation show that real conditions could be applied to the catalyst sample. Subsequently, the exhaust gas concentrations were monitored with a Fourier transform infrared spectrometer. The catalyst material used is PdO on Al2O3, common for methane oxidation. The measurements show that the CH4 conversion is higher under lean conditions, but is below complete conversion. In a final comparison between purely stoichiometric operation and dithering, the course of the CH4 conversion rate over the test period is examined more closely. In addition to sampling pre- and post-catalyst, the exhaust gas composition is measured spatially resolved within a catalyst channel using special measurement technology. In the temporal course of the CH4 emissions, a stabilizing effect due to the change of the operating mode can be seen, showing that dithering seems to prevent further deactivation.
End-effector with winding and scooping functions for folding and transporting various cloth parts after cutting
Authors: Zhu Yuzhe , Hirayama Motoki , Yamazaki Kimitoshi 
Published: May 2024

AbstractIn this study, we propose a novel end-effector that combines the characteristics of winding and scooping fabrics to grasp and categorically place various cloth parts cut by a cutting machine. In addition, we introduce a method for folding the fabric front and back into smaller dimensions, thereby reducing the space required for categorizing, placing, and packaging various clothes, which, to the best of our knowledge, is unique. Subsequently, we develop a method that autonomously determines folding strategies based on the different dimensions of cloth parts, allowing targeted processing of various cloth parts. This approach reduces the height demands of the robot and improves its capability to simultaneously handle multiple types of clothes. Finally, we evaluate the proposed end-effector and folding method in a simulated factory environment using T-shirt parts made of different materials.
Analyse prozessbezogener Verhaltensdaten mittels Learning Analytics: Aktuelle und zukünftige Bedeutung für die Unterrichtswissenschaft
Authors: Eberle Julia , Strauß Sebastian , Nachtigall Valentina , Rummel Nikol 
Published: May 2024

ZusammenfassungInternational entwickelte sich unter dem Begriff „Learning Analytics“ in den letzten Jahren ein Forschungsfeld, das sich auf das Sammeln, Auswerten und Anwenden komplexer, häufig multi-modaler und digitaler Verhaltensspuren fokussiert. Diese Verhaltensspuren, die Lernende und Lehrende in digitalen Kontexten hinterlassen, werden mit Hilfe computerbasierter Modelle oder mittels Verfahren des maschinellen Lernens ausgewertet, um Erkenntnisse über Lehr- und Lernprozesse zu gewinnen. Die Lehr-Lernforschung nähert sich derzeit langsam dem Feld der Learning Analytics an. Ein Potenzial von Learning Analytics für die Lehr-Lernforschung wurde demnach bereits erkannt, sodass ein Weiterdenken an dieser Stelle äußerst lohnenswert erscheint. Der vorliegende Beitrag skizziert daher die inzwischen bereits stark fortgeschrittene Forschung zu Learning Analytics und stellt anhand konkreter Beispiele das Potenzial von Learning-Analytics-Ansätzen für die Weiterentwicklung von Lern- und Instruktionstheorien dar. Insbesondere wird hier auf selbstreguliertes und kooperatives Lernen eingegangen sowie auf die Gestaltung von Lernumgebung und Unterstützung von Lehrkräften. Dabei mit- und weitergedacht werden sowohl Risiken und Herausforderungen von Learning Analytics (wie fehlende Kopplung zwischen Theorie und Empirie sowie ethische Aspekte) als auch Chancen (wie Erfassung der Komplexität und Zeitlichkeit von Lehr-Lernprozessen) von Learning Analytics für die Unterrichtswissenschaft und -praxis.