bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clear amniotic fluid aspiration syndrome: A novel description of an old entity
Authors: Robillard Pierre-Yves , Bonsante Francesco , Boumahni Brahim , Staquet Pierre , Richard Magali , Guinaud Julie , Trigolet Marine , Quiviger Sandrine , Iacobelli Silvia 
Published: June 2024

Background
Clear amniotic fluid aspiration syndrome (CAF-AS) is a very rare event occurring in 0.25% of our term clear amniotic fluids deliveries. The study’s aims were: 1. to characterize the risk factors and outcomes associated with Clear Amniotic Fluid Aspiration Syndrome and 2. to compare the outcomes of Clear Amniotic Fluid Aspiration to Meconium Aspiration.

Methods
This was an observational study over a 22-year period in a single level-3 medical center. Compared were parturient/labor characteristics and neonatal outcomes in cases with suspected Clear Amniotic Fluid Aspiration to cases suspected for Meconium Aspiration.

Results
Out of 79,620 term deliveries there were 66,705 (83.8%) clear amniotic fluids and 12,915 (16.2%) meconium stained amniotic fluid (MSAF). Of neonates born with clear amniotic fluid, 166 (0.25%) were diagnosed with Clear Amniotic Fluid Aspiration Syndrome (CAF-AS), while 202 (15.7%) of those born with MSAF, were diagnosed with aspiration syndrome (MSAF-AS). Both conditions had comparable rates of mild manifestation (67.5% vs 69.2%, p = 0.63). Persistent pulmonary hypertension (PPH) occurred 5 times less in CAF-AS than MSAF-AS (4% vs 20%, OR 0.17, P< 0.0001) Both conditions presented similar rates of surfactant without PPH (11.1% vs 13.4%, p = 0.87). There was 1 postnatal death in CAF-AS vs 10 in MSAF.

Conclusion
CAF-AS were quantitatively quite similar in terms of need of actual active intervention of the neonatologists in the delivery room (166 vs 202, i.e. in terms of numbers of cases and not prevalence) to MSAF-AS.We identified in these cases two major specific causes: hyperkinetic explosive deliveries in multiparas and long-lasting episodes of maternal hypotension due to epidural/spinal anaesthesia during labor. Out of 140 million births per year in the world, it should be of concern that 3 million cases are neglected nowadays. Future studies should evaluate if this CAF-AS should benefit from a more active intervention such as immediate endotracheal suction at birth, this clear fluid being very easy to suction.
Impact of nutrient warning labels on Colombian consumers’ selection and identification of food and drinks high in sugar, sodium, and saturated fat: A randomized controlled trial
Authors: Mora-Plazas Mercedes , Higgins Isabella Carolyn Aida , Gomez Luis Fernando , Hall Marissa G. , Parra Maria Fernanda , Bercholz Maxime , Murukutla Nandita , Taillie Lindsey Smith 
Published: June 2024

Objective
This study assessed the impact of nutrient warnings on product selection and ability to identify food products high in nutrients of concern in Colombia.

Methods
In an online experiment (May-June 2023), Colombian adults were randomized to a nutrient warning, guideline daily amounts (GDA), Nutri-Score, or no-label condition (n = 8,004). Participants completed selection tasks between two fruit drinks labeled according to their condition, one high in sugar and one not. Next, participants answered questions about products high in sugar, sodium, and/or saturated fat (“high-in” product). Finally, they selected which label would most discourage them from consuming a high-in product.

Results
Fewer participants (17%) exposed to the nutrient warning indicated they would purchase the high-sugar fruit drink compared to Nutri-Score (27%, Holm-adjusted (adj) p<0.001) and no label conditions (31%, adj p<0.001); there were no differences between the nutrient warning and GDA label (14%, adj p = 0.087). Compared to the nutrient warning, the GDA label was slightly more effective at helping consumers identify which drink was high in sugar (89% versus 92%, adj p<0.001), while the Nutri-Score and no-label conditions were less effective. Compared to all other conditions, nutrient warnings were more effective at helping participants identify that products were high in nutrients of concern, were more effective at decreasing intentions to purchase these high-in products and were perceived as more effective. Nutrient warnings were most often selected as the label that most discouraged consumption.

Conclusions
Nutrient warnings are a promising policy to help consumers identify and discourage consumption of products high in nutrients of concern.

Trial registration
Trial Registration: NCT05783726.
Effect of calcium treatment on inclusions in 38CrMoAl high aluminum steel
Authors: Li Yang , Chen Changyong , Zhang Cong , Ma Shuai , Yang Hao , Sun Meng , Cao Haibo , Jiang Zhouhua 
Published: June 2024

Abstract
Three parts of the experiment were mainly carried out in this research: the effect of Ca on inclusions in 38CrMoAl high aluminum steel under atmospheric pressure, the effect of pressure on the solubility of Ca in pure iron under pressurized conditions, and the effect of Ca on inclusions in 38CrMoAl high aluminum steel under pressurized conditions. The results indicated that Ca can significantly transform the inclusions such as Al2O3 and MgO·Al2O3 with high melting points into calcium aluminate inclusions with low melting points. It was found that the pressure condition can significantly improve the solubility of Ca in pure iron and molten steel, which provided reliable data reference and guidance for popularizing Ca treatment of steel under pressure conditions in the future. Finally, the mechanism of inclusion transformation after Ca treatment was put forward. In this study, the theoretical calculation of thermodynamics was closely compared with the experimental data. It was proposed that to modify the inclusions in high aluminum steel into calcium aluminate inclusions with low melting points, it is necessary to accurately control Ca in the target region.
L2 cognitive construal and morphosyntactic acquisition of pseudo-passive constructions
Authors: Zhong Yihang 
Published: June 2024

Abstract
Discussion of the theoretical underpinning of pseudo-passive constructions abounds in generative linguistics and comparative typology. However, the cognitive construal of and morphosyntactic acquisition of (un)grammatical English pseudo-passive constructions by Chinese-speaking L2-English users with different proficiency levels have never been investigated. It is worth examining whether proficiency level modulates constructional acceptability and cognitive construal, which would allow us to infer L2-English users’ morphosyntactic acquisition stages of pseudo-passive constructions. To fill this research gap, the study recruited 120 L2-English speakers with different levels of proficiency and 40 native English speakers to complete a grammaticality judgment test with an acceptance judgment scale from −2 to 2 for 40 ungrammatical pseudo-passive sentences and 40 fillers. Proficiency level significantly correlates with a firmer rejection of ungrammatical pseudo-passive sentences and cognitive construal which is more target-like. Significantly asymmetrical acceptance levels between two types of target ungrammatical constructions are also revealed for low (p = 0.002) and medium proficiency (p = 0.000) groups, demonstrating the type effect on grammaticality judgment and morphosyntactic acquisition.
A systematic review on potential analogy of phytobiomass and soil carbon evaluation methods: Ethiopia insights
Authors: Gelaye Yohannes 
Published: June 2024

Abstract
Forests play a crucial role in mitigating the impacts of climate change by sequestering carbon in their biomass and soil. However, Ethiopia faces the threat of soil carbon emissions due to deforestation and continuous cultivation. This study reviewed the analogies in phytobiomass and soil carbon evaluation methods in Ethiopia. Index-base and year-wise analysis methods were used for the compilation of the study. Developing nations, such as Ethiopia, duly enhance resilient measures to assess forest carbon stocks for effective climate change mitigation, particularly with reference to emissions from deforestation and degradation. Even though more than 90% of Ethiopia’s energy comes from forest biomass, deforestation significantly affects the carbon stored in aboveground biomass, which is the largest reservoir. Estimating forest biomass and carbon emissions entails uncertainties, with error ranges around ±50% for aboveground pools and ±90% for soil carbon pools. Various tier methodologies are employed by experts to estimate forest biomass and carbon stock emissions, with Tier 2 factors serving as default emissions but country-specific factors offering improved accuracy over Tier 1. Tier 3 methodologies require highly specific inventory data on carbon stocks in different pools and common measurements of key carbon stocks. Forest conservation enhances biodiversity, ecosystem resilience, and essential ecosystem services, fostering soil health, regulating water cycles, and supporting diverse plant and animal species. In conclusion, directing efforts towards forest conservation not only helps maintain biodiversity and ecosystem services but also significantly contributes to mitigating climate change by enhancing carbon storage capacities and reducing greenhouse gas emissions.
Design and antibacterial application of silver phthalocyanine-silver modified silicate immobilized on fabric
Authors: Wu Kuo-Hui , Huang Wen-Chien , Wang Je-Chuang , Yang Tsung-Han , Li Chia-Ling 
Published: June 2024

Abstract
Organic–inorganic composite antibacterial materials based on silver phthalocyanine-silver (AgPc/Ag) and aminosilane-modified silicate (Ormosil) were synthesized by sol-gel method and in-situ reduction method. The objective of this study was not only the synthesis of Pc-Ormosil and AgPc-Ormosil/Ag composites but also investigated the bacteriostatic ability of the Pc-Ormosil and AgPc-Ormosil/Ag modified fabrics and the relationship between the antibacterial property and the content of composites on non-woven fabric was discussed. Moreover, the laundering durability of the bacteriostatic of the AgPc-Ormosil/Ag-treated fabrics was also examined. The bacteriostatic ability of the Pc-Ormosil and AgPc-Ormosil/Ag modified fabrics against Gram-negative Pseudomonas aeruginosa, Escherichia coli and Gram-positive Staphylococcus aureus, Bacillus subtilis were confirmed by the zone of inhibition and the plate-counting method. The bacteriostatic ability remains even after one laundry cycle.
Preparing new secondary science teachers in the context of sustainable development goals: green and sustainable chemistry
Authors: Bradley John Dolman , Moodie Peter 
Published: June 2024

Abstract
School science teachers have an important role to play in preparing young people for a sustainable future. Yet their teaching is usually constrained by national school curricula, which may be slow to change to address the issues of sustainable development. Initial teacher education should anticipate the required changes in school curricula so that newly qualified teachers are better equipped to implement the changes when they happen. This paper is based upon the situation prevailing in South Africa, a country with some of the best and some of the worst schools in sub-Saharan Africa. It suggests ways that the BEd course for physical science education student teachers can be developed toward education for sustainable development, while accepting the constraints of the national curriculum, which has become the defining structure of the BEd.
Case of lead poisoning secondary to intake of herbal medicine for diabetes mellitus in a tertiary care hospital in Kerala
Authors: Thomas Junith , Sebastian Rohini , Anil Kumar C R , Rafi Aboobacker Mohamed 
Published: June 2024

Summary
Although most published cases of lead poisoning come from occupational exposures, some traditional remedies may also contain toxic amounts of lead. Here, we report the case of a 58-year-old female who presented with abdominal pain, generalized tiredness, and decreased food intake, with anemia and elevated levels of lead. The patient was found to be taking herbal capsules for diabetes prior to the presentation. This case highlights the need for increased awareness that some herbal remedies may contain potentially harmful levels of heavy metals, and people who use them are at risk of developing associated toxicities.

Learning points

Individuals who support traditional medicine often incorrectly believe that herbal remedies for diabetes are free from side effects, leading them to favor these treatments over contemporary medications.

Herbal medications are freely available online, even without a prescription.

The accessibility of herbal medicines without prescriptions, coupled with the false belief in their lack of side effects, misleads educated individuals toward quackery treatments. Misinformation spread via social media exacerbates this issue.

Heavy metals are present in toxic levels in the drugs, causing complications.

Lead is the most common heavy metal found in such herbal medicines.

Lead poisoning leads to anemia and other systemic complications which could have been fatal if not found in time.
Hamster spermatozoa incorporate hypotaurine via TauT for self-protection
Authors: Takei Gen L , Horibata Yasuhiro , Toyama Fubito , Hayashi Keitaro , Morita Asuka , Ouchi Motoshi , Fujita Tomoe 
Published: June 2024

In brief
Mammalian spermatozoa actively generate reactive oxygen species (ROS) during capacitation, a maturational process necessary for fertilization in vivo. This study shows that hypotaurine, a precursor of taurine present in the oviduct, is incorporated and concentrated in hamster sperm cells via the taurine transporter, TauT, for cytoprotection against self-produced ROS.

Abstract
To achieve fertilization competence, mammalian spermatozoa undergo capacitation, during which they actively generate reactive oxygen species (ROS). Therefore, mammalian spermatozoa must protect themselves from these self-generated ROS. The mammalian oviductal fluid is rich in hypotaurine, a taurine precursor, which reportedly protects mammalian spermatozoa, including those of hamsters, from ROS; however, its precise mechanism remains unknown. This study aimed to elucidate the mechanism underlying hypotaurine-mediated protection of spermatozoa from ROS using hamsters, particularly focusing on the taurine/hypotaurine transporter TauT. The effect of hypotaurine on sperm motility and ROS levels was tested using sperm motility analysis and the CellROX dye and luminol assays. RNA sequencing analysis was performed to verify TauT expression. We found that hypotaurine was necessary for maintaining sperm motility and hyperactivated motility. Hypotaurine did not scavenge extracellular ROS but lowered intracellular ROS levels and was incorporated and concentrated in hamster spermatozoa. TauT was detected at both mRNA and protein levels. β-Alanine blocked hypotaurine transport, increased intracellular ROS levels, and inhibited hyperactivation. Elimination of Na+ or Cl− ions inhibited hypotaurine transport and increased intracellular ROS levels. Thus, these results indicated that hamster spermatozoa incorporated and concentrated hypotaurine in sperm cells via TauT to protect themselves from self-generated ROS.
Closer to Home: A Quality Improvement Initiative to Optimize Satellite Site Bed Capacity
Authors: Herrmann Lisa E. , Hubbell Brittany , Taylor Abigail , Duma Elena , Warniment Amanda , Smith Lauren , Mailloux Eric , Szczepanski Karen , Schmidlin Emily , Mitchell Michelle , Kientz Liesl , Albrecht Jennifer , White Christine M. , Statile Angela M. 
Published: June 2024

BACKGROUND
The coronavirus disease 2019 pandemic resulted in the underutilization of inpatient beds at our satellite location. A lack of clarity and standardized admission criteria for the satellite led to frequent transfers to the main campus, resulting in patients traveling larger distances to receive inpatient care. We sought to optimize inpatient resource use at the satellite campus and keep patients “closer to home” by admitting eligible patients to that inpatient unit (LA4). Our aim was to increase bed capacity use at the satellite from 45% to 70% within 10 months. Our process measure was to increase the proportion of patients needing hospitalization who presented to the satellite emergency department (ED) and were then admitted to LA4 from 76% to 85%.

METHODS
A multidisciplinary team used quality improvement methods to optimize bed capacity use. Interventions included (1) the revision and dissemination of satellite admission guidelines, (2) steps to create shared understanding of appropriate satellite admissions between ED and inpatient providers, (3) directed provider feedback on preventable main campus admissions, and (4) consistent patient and family messaging about the potential for transfer. Data were collected via chart review. Annotated run charts were used to assess the impact of interventions over time.

RESULTS
Average LA4 bed capacity use increased from 45% to 69%, which was sustained for 1 year. The average percentage of patients admitted from the satellite ED to LA4 increased from 76% to 84%.

CONCLUSIONS
We improved bed capacity use at our satellite campus through transparent admission criteria and shared mental models of patient care needs between ED and inpatient providers.
Genomic insights into NDM-1-producing Pseudomonas aeruginosa: Current status in a Bulgarian tertiary hospital and on the Balkans
Authors: Strateva Tanya , Keuleyan Emma , Peykov Slavil 
Published: June 2024

AbstractThe present study aimed to explore the genomic characteristics of eight New Delhi metallo-β-lactamase-1 (NDM-1)-producing carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates from a Bulgarian tertiary hospital (2021–2023) in comparison to blaNDM-1-positive strains originating from the Balkans. Antimicrobial susceptibility testing, phenotypic assays for carbapenemase activity, PCR screening, whole-genome sequencing (WGS), and phylogenomic analysis were performed. Seven of the CRPA isolates investigated (Minimum inhibitory concentration values of imipenem and meropenem >32 mg L−1) were also resistant to piperacillin-tazobactam, ceftazidime, ceftazidime-avibactam, cefepime, ceftolozane-tazobactam, amikacin, tobramycin, ciprofloxacin, and levofloxacin, but were susceptible to colistin (0.5–2 mg L−1) and cefiderocol (0.25–1 mg L−1). The P. aeruginosa Pae57 isolate (designated Pae57) remained susceptible to aminoglycosides as well. WGS uncovered the co-existence of blaNDM-1 and blaGES-1. The isolates belonged to the ST654 high-risk clone, except for Pae57 (ST611). Alignment against reference sequences revealed the presence of a Tn21 transposon harboring bleMBL–blaNDM-1–ISAba125. It was similar to that found in the P. aeruginosa ST654 NDM1_1 strain (GCA_020404785.1) from Serbia. Phylogenomic analysis of our isolates indicated that seven of them (ST654) differed from each other in no more than 44 single-nucleotide polymorphisms (SNPs). Pae57 (ST611) was strikingly different (>21,700 SNPs) compared to all Balkan strains. In conclusion, to our knowledge this is the first report of blaNDM-1-positive P. aeruginosa ST611 isolation, which indicates the transmission dynamics of this determinant between high-risk and potentially high-risk P. aeruginosa clones. Obtained results unveil the dissemination of clonally related NDM-1-producing P. aeruginosa strains in the monitored hospital for approximately a 2-year period.
Utilizing melanoidin consuming microalgae for electricity generation and wastewater treatment via photosynthetic microbial fuel cell
Authors: Chaijak Pimprapa , Changkit Nopparit , Kongthong Alisa 
Published: June 2024

Aim of the studyIn our investigation, the freshwater microalgae Chlorella sp. BF01 to degrade the melanoidin in the palm oil mill effluent and generate electricity in the photosynthetic microbial fuel cell (PMFC).Material and methodsThe freshwater microalgae Chlorella sp. were used in a PMFC consortium for the degradation of melanoidin and electricity generation. The removal (%), electrochemical properties, and biomass recovery were monitored without adding exogenous medium.Results and conclusionsIn this study, lipid-producing microalgae were employed as whole-cell biocatalysts in a PMFC using palm oil mill effluent as a substrate. The maximal melanoidin removal of 79.54±0.45% was gained. The maximum power density reached was 3.98±0.10 W/m3. The research presents findings that pave the way for the practical implementation of this innovative approach on an industrial scale.
Long-term anticoagulant therapy in the aspect of secondary prevention of recurrent pulmonary embolism
Authors: Shmidt E. A. , Penskaya T. Yu. , Gruzdeva O. V. , Berns S. A. , Karetnikova V. N. , Barbarash O. L. 
Published: June 2024

Aim. To determine differences in laboratory coagulation parameters using routine and integral monitoring methods in patients depending on anticoagulant therapy >12 months after pulmonary embolism (PE) with a high recurrence risk.Material and methods. The study included 72 patients who, according to indications, received long-term anticoagulant therapy >12 months due to a high risk of recurrent thromboembolism. During the follow-up period (15-20 months from the first pulmonary embolism episode), the plasma coagulation parameters were studied using a conventional panel and D-dimer assessment, as well as a thrombin generation test and thrombodynamics. Patients adherent to prolonged anticoagulation were included in group 1. During the collection period, 8 patients independently stopped taking anticoagulants, despite the high risk of recurrent pulmonary embolism (group 2).Results. There were no significant differences in coagulation parameters and D-dimer levels between the studied groups of patients. In the group of patients continuing to take anticoagulants, there was an increase in clot growth delay parameters in comparison with patients of group 2 according to the thrombodynamics results (p=0,046) and the thrombin generation test in platelet-poor plasma in comparison with reference values (p=0,001).Conclusion. Long-term anticoagulant therapy effectively prevents recurrent venous thromboembolism. In patients after primary pulmonary embolism who refuse anticoagulation, the clot growth delay values are shortened, which indicates an increased risk of recurrent venous thromboembolism. The most stable plasma coagulation parameters are observed in patients taking direct oral anticoagulants.