bluuebunny/crossref_metadata_2025_split huggingface dataset:
P01-144 - A Lifestyle Intervention for Panic Disorder in Primary Care and an Explanatory Model
Authors: Lambert R. ,   Shared Decision-Making Unit of the Health and Social Sciences Research Institute, UEA, Norwich
Published: June 2010

ObjectivesTo examine the clinical and cost-effectiveness of a lifestyle-based approach to treating anxiety and Panic Disorder in Primary Care. To present evidence from an explanatory model.MethodsA Pragmatic Randomised Controlled Trial was conducted comparing a lifestyle intervention with routine GP care. The lifestyle intervention used patient diary data focusing on diet, fluid intake, habitual lifestyle drug use (alcohol, nicotine and caffeine) and exercise, to influence mood and behaviour change. Following the MRC (2008) recommendation on developing and evaluating complex interventions, an explanatory model was developed.Results31 Lifestyle arm and 36 GP care arm patients completed to analysis. A significant improvement in Beck Anxiety Inventory scores was observed at end of treatment (Lifestyle 29.5 to 9.2; GP 29.4 to 17.2; p< 0.001) although non-significant at 10 month follow-up (Lifestyle 13.3: GP 16.4; p=0.167). Results were comparable with full CBT and improved compared with medication. Cost-effectiveness analysis showed that If maximum willingness to pay peradditional QALY is £30,000, this represents an 86% chance that a lifestyle intervention provides value for money over 10 months. Modeling shows a broad range of factors influencing anxiety and panic responses, indicating that lifestyle interventions impact at a different point in the system to medication and psychological approaches.ConclusionsEvidence shows that a lifestyle-based intervention provides an additional, cost-effective intervention and significantly improved symptom profile for anxiety and panic disorder compared with routine GP care. It impacts on both physiological and cognitive symptoms. Modeling suggests broader application to other mental health problems.
P01-145 - Lamotrigine Administration in Panic Disorder with Agoraphobia
Authors: Masdrakis V. , Papadimitriou G. , Georgantopoulos G. , Kalogera E. , Konstantakopoulos G. , Oulis P. 
Published: June 2010

ObjectivesThe potential efficacy of various antiepileptic drugs in the treatment of Panic Disorder (PD) with (PDA) or without Agoraphobia has been studied in clinical trials, though not as yet that of lamotrigine (LTG).MethodsWe administered LTG to four outpatients with PDA according to DSM-IV-TR criteria, as an augmentation therapy (three patients with chronic and severe agoraphobia) or monotherapy (one drug-naïve patient with first-onset PD and moderate agoraphobia). LTG was titrated up to 200 mg/day within a 6-week period and remained at that dosage for another eight weeks. The patients were clinically monitored every week, while standard psychometric evaluations were completed at baseline and after the end of the trial.ResultsThe patient under LTG monotherapy exhibited a complete remission of his panic attacks and a significant improvement in agoraphobic avoidances and other outcome measures. Some improvement was evident after the clinical trial in one more patient who exhibited a complete remission of her spontaneous panic attacks and in another patient who exhibited reductions in both her anxiety levels and PD-related cognitions.ConclusionsAlthough anecdotal and thus in need of replication in well-designed large studies, our preliminary findings suggest that LTG as monotherapy (at 200 mg/day) might improve significantly PDA symptomatology in a proportion of drug-naïve patients with recent-onset PD and moderate agoraphobia, while LTG as augmentation agent (at 200 mg/day) might improve at least some aspects of the clinical psychopathology of PD patients with chronic and severe agoraphobia.
P01-147 - Olanzapine Augmentation for Treatment-resistant Obsessive-compulsive Disorder
Authors: Darghal M. 
Published: June 2010

ObjectiveWe report the case of a patient with treatment-resistant obsessive-compulsive disorder (OCD) that had a significant reduction in obsessive-compulsive symptoms after the addition of the atypical antipsychotic to the Selective serotonin reuptake inhibitors (SSRIs)MethodsMs. A, a 31-year-old woman, with no family history of psychiatric disorders has been suffering from OCD for 4 years. His main obsession was contamination, and his compulsions (washing rituals) occupied 12 hours a day, rendering him unfit for work in there house or employment. Various treatments had been ineffective. His Yale-Brown Obsessive Compulsive Scale total score (Y-BOCS) at his first psychiatric interview was 38. He was taking clomipramine, sertraline, haloperidol, amisulpride, and alprazolam. Previous trials did not result in clinically meaningful responses (side effects prevented titration to higher doses), however all psychiatric drugs were discontinued except sertraline (100 mg/day) associated with olanzapine (5 mg/day).ResultsAfter 10 days, Ms. A reported significantly lessened anxiety and, after three months, significantly lessened obsessive-compulsive symptoms. By the fourth month, his symptoms were occurring for only few hours week (Y-BOCS total score of 16). At this point, the addition of olanzapine would appear to be a useful short- and long-term strategy for augmenting SRI effectiveness in resistant OCD patients.ConclusionCurrent options for treatment-resistant OCD include switching to an alternative selective serotonin reuptake inhibitor or augmentation with other agents. Our case suggests that olanzapine may be an option for treatment-resistant OCD, but controlled studies are needed to substantiate this observation.
P01-152 - Clinical Aspects of Anxiety and Depression in Multiple Sclerosis
Authors: Papari C.-A. , Cozaru C.G. , Papari A. 
Published: June 2010

ObjectivesSpecialty studies show that the emotional state of the patient with Multiple Sclerosis is deteriorating in relation to the phisycal condition and medication and motor re-education without psychological re-education is just not effective. The present paper tries to make an evaluation of the anxiety and depression in pacients with Multiple Sclerosis.MethodTwo groups, each composed by 30 subjects(even proportions between men and women). The research group consisted of pacients diagnosed with MS and the control group, with subjects selected from the general population, not diagnosed with any chronic disease. Two tests were used: State Trait Anxiety Inventory and Beck Depression Inventory.ResultsAnxiety, as a trait of a personality is significantly evidenced in patients diagnosed with MS, in comparison to the control group. Depresive states, with variable intensity are also more frequent at the research group, compared to the control group. The highest average of the depression was recorded in subjects diagnosed with MS for 1 year. These results were coherent with the high scores of the patients from the research group, as well as the difference that is significant from the statistical point of view (p>0.10).ConclusionsThe frequency of the psychiatric disturbances in MS is much higher than the general population. Depression and anxiety contribute greatly to the development of the disability in this particular disease.
P01-154 - The Evaluation of Anxiety Prevalence between Students of First and Last Semesters of Ardabil University
Authors: Rezaei Ghalechi E. , Kazemi R. 
Published: June 2010

BackgroundThe aim of this study is the investigation of anxiety prevalence between first semester and last semester students in university and this research explains the rate of students’ anxiety in university's terms.MethodsThis investigation is a descriptive study that 120 students (60 F, 60 M) in Ardabil University from the first and final semesters as the accidental samples by questionnaire are selected. We used Cottle Anxiety test and gained results by SPSS and statistical analysis.ResultsFirst semester students' anxiety rate was (50%) and final semester students too (50%). (57.7%) of cases were native. most of them (93.3%) was jobless and single (87.5%).ConclusionThis study shows that there isn’t meaningful relation between rate of Anxiety and age, situation of marriage, occupational situation and living place in first or last semester students of Ardabil University.
P01-158 - The Level of Anxiety Symptoms Prior a Thoracic Surgery is Associated with Gender and Age
Authors: Sikaras C. , Moussas G. , Voyagis G. , Maria A. , Anagnostopoulou M. , Tselebis A. , Bratis D. , Moulou A. , Ilias I. , Toutouzas K. , Kiritsi E. , Stefanadis C. 
Published: June 2010

ObjectivesAn operation is undoubtedly a stressful event, which can induce emotional, cognitive and physiological reactions in preoperative patients. Aim of our study is to investigate the associations between the levels of state - trait anxiety and the demographics (gender and age) in patients prior a thoracic surgery.MethodsSeventy-six (57 males and 19 females) patients, with ASA I-III and with mean age 45.65±15.17 years were included in the study. All subjects fulfilled the Spielberger State-Trait Anxiety Inventory (SSTAI), 12 - 15 hours before the thoracic surgery.ResultsMean state and trait anxiety scores were 42.35±11.50 and 38.55±9.03, respectively and presented a strong positive correlation (Pearson Correlation, p< 0.001, r=0.585). Percentages of 30.3% and 13.2% of the sample were presented with clinically significant anxiety levels (t-test, p=0.001). Females appeared with higher state (t-test, p=0.001) and trait (t-test, p=0.076) anxiety scores compared to males. As to age, we observed a negative correlation with the levels of state and trait anxiety. (Pearson Correlation, p=0.05, r=-0,226 and p=0.006, r=-0.313, respectively).ConclusionsOur findings suggest that females and younger patients are more vulnerable to anxiety symptoms prior a thoracic surgery. Thus, gender and age should be taken into account for the preoperative assessment in order to develop supportive psychological interventions.
P01-166 - Transitioning onto OROS MPH is Associated with Improved Functioning and Quality of Life in Adolescents with ADHD
Authors: Alfred A. , Lindermueller A. , Mattejat F. , Dichter S. , Schaeuble B. 
Published: June 2010

ObjectiveTo explore functionality and quality of life outcomes in adolescents with ADHD transitioning from IR MPH, ER MPH or ATX onto PR OROS MPH.MethodsPooled analyses of two similar 12 week open label, flexible dose, non-interventional trials exploring outcomes in adolescents with ADHD (ICD-10) transitioning from either IR / ER MPH, or Atomoxetine onto PR OROS MPH. Connor's parents rating scale (CPRS), children's global assessment scale (CGAS) and quality of life (ILC) were measured.Results186 adolescents (84.4% boys; median age 14yrs) were analyzed. Starting dose of OROS MPH was based on clinical judgment. Median dose of PR OROS MPH at baseline and endpoint was 36mg/day. Functionality based on C-GAS as well as burden of disease scores measured in parents and adolescents improved at endpoint (p< 0.001). 80% girls and 67% of boys achieved an at least 30% reduction on CPRS. ILC-LQ0-28 in adolescents and their care givers improved (p< 0.05). 56 adolescents (30,1%) experienced at least one treatment emergent adverse event (AEs≥4% were insomnia (4,8%), headache (3,7%), muscle twitches (3,2%).ConclusionAdolescents with ADHD transitioning onto PR OROS MPH showed clinically relevant improvement in daily functioning and quality of life aspects. Burden of disease in patients and their care givers was lowered.
P01-167 - Help Seeking Process for Children and Adolescents Attending Child Adolescent Psychiatry Service in Tirana
Authors: Alikaj V. 
Published: June 2010

In Albania there is a need for data to support services for children and adolescents mental health, a needs assessment and also need for epidemiological data relevant to local circumstances.Objectiveof the help-seeking pathway study for children and adolescent mental health problems was to investigate all the potential routes to Child/Adolescent Psychiatry Clinic-University Hospital Center (CAPC-UHC) Tirana and to investigate factors influencing this process for children at risk.MethodParticipants were 5-18 years old, newly referred children/adolescents in CAMHS during 2006. Measures used were Strengths and Difficulties Questionnaire for parents/children, Pathways Encounter Form. Patterns of care seeking, durations and previous treatments for diagnosis within ICD-10 groups were prescribed. Analysis: Comparisons between groups, diagnosis and predictive factors influencing help seeking care.ResultsThe child neurologist played an enormous role in referring the child to CAPC, followed by adult psychiatrist or GP. The most frequent diagnosis resulted to be pervasive developmental disorder (28.4%), phobic and anxiety disorders (19.1%), somatoform and dissociative disorders (17.3%), hyperkinetic and conduct disorder (15.4%).ConclusionsThis is the first study investigating the help seeking process to psychiatric care to CAPC Tirana-Albania. There is a need for further research on a general population level, including primary care settings, preschools and schools based services, because a clearer understanding is required about barriers to service use and also identifying children/adolescents with psychiatric disorders not referred to the specialist. These results could contribute to assisting a successful implementation of the National Service Framework for Children/Adolescents.
P01-169 - Psychometric Properties of Two new Screening Instruments for Depression in Childhood and Adolescence: Findings from a Pilot Study
Authors: Allgaier A.-K. , Frühe B. , Pietsch K. , Schulte-Körne G. 
Published: June 2010

ObjectivesDepression is highly prevalent, but often unidentified in pediatric primary care. Without treatment, early-onset depression often leads to psychosocial impairment and is associated with a high risk of recurrence, chronicity and comorbid mental illnesses. While depression screening is recommended for adults in the primary care setting, screening instruments for children and adolescents are still rare. Therefore, the study group developed two depression screeners in German language, specifically designed for this age group. In a pilot study, psychometric properties of these screeners are computed.MethodsThis is a cross-sectional study of a pediatric clinic sample of 100 children and adolescents aged 9-16 years. To assess screener performance, item analysis and realibility measures were calculated. Further, validity measures were computed, using a standardized clinical interview as gold standard criterion for depression diagnosis.ResultsThe pilot study is ongoing until January 2009. Items analysis results are presented as well as internal consistency. Validity measures are illustrated by ROC curve analyses.ConclusionsBased of the results of the pilot study, the screening instruments will be revised. To confirm our preliminary findings, the screeners will be tested in a larger sample during the main study. If the depression screeners have proven to be reliable and valid, in the long run they can be implemented in pediatric primary care as a diagnostic aid.
P01-170 - Bullying and Depression among Children
Authors: Aoki T. , Miyashita M. , Inoko K. , Kodaira K. , Osawa M. 
Published: June 2010

ObjectivesTo investigate the relations between acting the bully, being bullied, seeing someone bullied and depression in children.Methods108 children (6 to 13 years of age, students of one school - 1st to 7th grade) participated in this study. They completed questionnaires regarding acting the bully, being bullied and seeing someone bullied. The questionnaires include 5 psychological bully questions respectively, and they consist of 15 questions. The Center for Epidemiologic Studies Depression Scale (CES-D) Japanese-version was also completed by the children.Results12 children scored 16 or higher on CES-D. The children were supposed depression. 50 children answered “yes” to one or more question of 5 ones with regard to acting the bully. They were supposed acting the bully. 67 children and 75 children were supposed being bullied and seeing someone bullied respectively. Logistic regression analysis was performed to determine whether acting the bully, being bullied and seeing someone bullied were associated with depression.Being bullied was significantly associated with depression [Odds ratio 21.82 (95% confidence limits 1.86-256.20)]. Acting the bully was associated with depression [Odds ratio 4.681(95% confidence limits 0.767-28.580)]. Seeing someone bullied had no association with depression [Odds ratio 0.10(95% confidence limits 0.01-0.74)].ConclusionsBeing bullied greatly affected the emotion. Younger children are said to be more likely to be victims of bullying. Appropriate interventions in the school children are needed.
P01-172 - Overview of Child Psychiatry in a Developing Country
Authors: Bakht M. 
Published: June 2010

BackgroundVarious epidemiological studies indicates that emotional & behavior problems in children are equally prevalent in developing & developed countries. In a developing country such as Bangladesh the daily livelihood & combating common childhood diseases are the foremost concern, and the mental health of children is often neglected.ObjectivesThis study will review an overview of child psychiatry in a developing country, focusing on the lack of existing infrastructure, challenges facing children mental health services & what steps to be taken to develop mental health services in Bangladesh.MethodsCritical review of various literature on the topic.ResultsChild psychiatry is gravely under recognized & underdeveloped in Bangladesh. There is lack of basic infrastructure in the field of child psychiatry. Top most mental disorders amongst children in Bangladesh are behavior disorders & anxiety disorders. These problems are not just restricted to urban regions of Bangladesh; there is also significant levels of emotional problems amongst children in rural areas of Bangladesh.ConclusionPoverty, malnutrition, illiteracy, & in recent years, through rapid urbanization of the country, the social & family structure is breaking down, which is contributing in development of mental health disorders amongst children. There is definite lack of infrastructure, awareness & availability of mental health services for children. However, plenty of avenues exist, through which child psychiatric services can be developed in the country.
P01-173 - Traumatic Impact on the Young mind in Response to Disasters: an Approach to Psychosocial Intervention
Authors: Bakht M. 
Published: June 2010

BackgroundTraumatic events such as tsunamis, wildfires, war, cyclones, etc. have a lasting effect on children's emotional well-being. The psychological impacts are multifactorial & reaction is also varied depending on the individual.ObjectivesThis study will review the psychological impact on children's minds following exposure to traumatic events & will identify the evidence based psychosocial approach of intervention.MethodsCritical review of literature on the topic.ResultsThe severity of impact depends on exposure to the traumatic event, but minimum exposure can also be harmful. The level of trauma, proximity, duration of exposure, evidence of psychopathology before trauma exposure & disruption in social support networks consistently emerge as strong predictors of psychopathology following exposure to trauma with response to mood, anxiety or behavioral manifestation. Socioeconomic disadvantages that follow disaster predict long-term problems. A positive correlation between children's & parents symptomatology has been noted. Intervention strategies include screening children at risk,triage & referral,community based intervention & trauma focused treatment programs. CBT emerges as the best validated therapeutic modalities for children experiencing trauma related mood & anxiety symptoms.ConclusionPsychological impact resulting in trauma to children could be enormous. Good psychosocial management following a disaster with effective follow through & broad care planning may lessen the long term impacts.
P01-179 - Family Relationships in Children and Adolescents with Behavioral Disorders
Authors: Burgic-Radmanovic M. , Burgic S. 
Published: June 2010

ObjectiveThe children and youth mental health is a dynamic and developing process that is result of their interactions with family, school, community and surrounding. The goal is to show the influence of family disfunction on behavior disorders among children and youth, especially the presence of negligence and abuse of children. The aim of this research is to show the presence of comorbid diseases and influence of low socio-economic family status as well.MethodThe research is retrospective study taken by 64 patients (36 girls and 28 boys), age between 7 and 18, at Department of child and adolescent psychiatry in Banja Luka. We analised socio-demografic status, comorbid diseases, the presence of negligence and abuse among youth and behavior disorders. Our own questionnaire, made for this research, socio-psychiatric and clinical records and case history are used in this study. The results are analised by graffics and tables.ResultsThere is significant higher number of boys, age under 14 years old, statistic lower socio-economic status, the presence of family violence, school dificulties, quiting the school. There is significant number of girls with comorbid disease.ConclusionFamily can influence on apperance of mental disorders in their children through family disfunction, frequent conflicts, negligence and family violence, the presence of severe diseases, low socio-economic status, psycho-traumatic events and stressful situations.
P01-183 - Policy, Evidence and Practice in Mental Health Care: Infant Mental Health
Authors: Nikiten S. , Cawthorpe D. , Hawkins E. , Wilkes C. 
Published: June 2010

ObjectivesHealth care policies should be implemented to provide the proper care for children with mental health disorders and there is a need for improved infant and early childhood mental health assessment. In this paper we examine how system data reflecting program practice meet to inform advances in developing infant mental health policy.MethodsData from the Collaborative Mental Health Care (CMHC) program, a consultation based service in the focusing on the early identification of children (aged 0-5) at significant risk for developing mental health problems, was analyzed in comparison to those not coming into contact with such specialized services.ResultsCompared to others of the same age, those with CMHC involvement waited less time [mean days 13.7 (S.D. 32.3) vs. mean days 69.3 (S.D. 180.3] and had shorter lengths of stay [mean days 139.9 (S.D. 119.3) vs. mean days 232.4 (S.D. 329.7] and proportionately fewer registrations.ConclusionsEarly identification of children's mental health concerns through supporting the community through specialized consultation and promoting resiliency can significantly reduce mental health service utilization by offering more specific and specialized information, referral or treatment services for infants and very young children. The policy implications are self-evident: All provinces require specialized mental health services for infants and very young children in order to better serve children and increase service capacity.