bluuebunny/crossref_metadata_2025_split huggingface dataset:
#2681 Impact of sharing anti-SARS-CoV-2 antibody levels with Kidney Transplant Recipients on adherence to preventive measures and incidence of COVID-19
Authors: Bouwmans Pim , Sanders Jan-Stephan F , Hilbrands Luuk , Reinders Marlies , Bemelman Frederike , Abrahams Alferso , De Vries Aiko , Brandts Lloyd , Vervoort Hanneke , Gansevoort Ronald , Hemmelder Marc , Messchendorp Lianne 
Published: May 2024

Abstract

Background and Aims
Preventive measures are effective against COVID-19 in kidney transplant recipients (KTR). We analysed whether sharing the antibody level after COVID-19 vaccination with these patients is associated with a change in adherence to preventive measures and if so, with the incidence of COVID-19.

Method
We included adult KTR who participated in the Long-term Efficacy and Safety of SARS-CoV-2 (LESS CoV-2) cohort study. Anti-RBD IgG levels were measured using ELISA (Sanquin, Amsterdam) one month after the third COVID-19 vaccination. Adherence to nine preventive measures was self-reported on a 5-point Likert scale, before and after the antibody level was shared. Based on their antibody level, patients were classified as high-responders (&gt;300 BAU/mL), low-responders (50-300 BAU/mL), or non-responders (&lt;50 BAU/mL) to COVID-19 vaccination. Information about incidence of COVID-19 was collected until 6 months after sharing the antibody level. For analysis, we calculated average adherence to all preventive measures with a range from 1 to 5. Multivariable logistic regression analysis was performed to assess an association between change of adherence and incidence of COVID-19.

Results
We included 1928 KTR, of whom 1058 high-responders, 548 low-responders, and 322 non-responders. After sharing antibody levels, adherence to preventive measures decreased in the total population (before: 4.11 [3.60-4.44] versus after: 4.00 [3.23-4.44], p &lt; 0.001). This change of adherence was more pronounced in high-responders than in low- and non-responders (0.21 ± 0.68, 0.11 ± 0.56, and 0.14 ± 0.56 respectively, p = 0.02). During follow-up, COVID-19 was diagnosed in 627 of 1928 KTR (33%). In high-responders, the incidence of COVID-19 was higher in patients with decreased adherence compared to patients with increased adherence (decreased: 196 of 617 [32%] versus increased: 114 of 441 [26%], p = 0.04). The change of adherence in high-responders was associated with COVID-19 (OR 0.73 per unit increase [0.60-0.89], p = 0.002), but not after correction for confounding (aOR: 0.86 [0.68-1.07], p = 0.2).

Conclusion
Sharing anti-SARS-CoV-2 antibody levels with KTR was associated with a decrease in adherence to preventive measures, especially in KTR with a high antibody response to vaccination. In these high-responders, the risk of COVID-19 increased with decreasing adherence to preventive measures. This was not observed in low- or non-responders. Sharing antibody levels with KTR influences adherence to preventive measures and risk of COVID-19, and therefore requires careful communication.
#1275 Post-transplant renal anaemia: a call to action from a national study in routine clinical practice
Authors: Portoles Jose , Crespo Marta , Rodrigo Emilio , Calabuig Maria Asuncion Sancho , Montero Nuria , Blanca María Auxiliadora Mazuecos , Dalmau Alex Gutierrez , Pascual Julio 
Published: May 2024

Abstract

Background and Aims
Post-transplant anaemia (PTA) is common, frequently unnoticed and carries associated risks. Current guidelines consider the same treatment recommendations and goals for these patients as for chronic kidney disease-non dialysis (CKD-NDD). Previous reports demonstrated low awareness and management that could improve. Aims: To describe current anaemia management, goals, and adherence to guidelines in a representative sample of kidney transplant (KT) recipients.

Method
Retrospective nationwide multicentre study including patients from 8 KT hospitals. Nephrologists collected demographics, comorbidities, KT data and immunosuppressive therapy and data related to anaemia management (laboratory values, previously prescribed treatments, and subsequent adjustments) from electronic medical records. We classified as early anaemia that within the first 6 months. The European statement on KDIGO guidelines was the reference for definitions, drug prescriptions and targets.

Results
We included 297 recipients with PTA aged 62.8 y (SD 13.6) and 60% male. They had received a graft from donors after cardiac death or brain death) (61.6%. 31.1% respectively) a median of 2.5 years [0.5-8.7] before. A total of 158 patients were on treatment with erythropoietin stimulating agents (ESAs) and the distribution of haemoglobin (Hb) and iron are summarized in Table 1. Among 110 patients on ESA treatment but without iron prescription, 44 had an indication to receive iron and 30 of them had absolute iron deficiency (ID).
Only 39/158 patients exceeded the ESA resistance index (ERI) limit, and this condition was more frequent in early PTA (26.1 vs 9.2%). Absolute or functional ID accounted for the majority of ESA resistance (28.2 vs 17.1; p &lt; 0.001).

Conclusion
Hemoglobin levels in these patients are within the upper KDIGO. Iron therapy continues to be underused (especially intravenous), while iron deficiency and prior events explain most of ESA hyporesponsiveness. We identify missed opportunities for accurate prescription targeting and adherence to guidelines.
#738 Blood type mismatch between donor and recipient is a risk factor for BK viremia one year after kidney transplantation
Authors: Bielopolski Dana 
Published: May 2024

Abstract

Background and Aims
Kidney transplanted recipients are at increased risk of infections, including BK virus, for which there is no specific treatment. Current prevention strategies include surveillance and risk stratification. We sought to estimate the contribution of non-identical but compatible (mismatched) ABO blood types to the risk of BKV viremia.

Method
A retrospective single-center study was conducted in kidney transplant recipients between 1/1/2011 and 1/12/2021. The primary outcome was viremia (&gt;10,000 copies per ml in two consecutive measurements at least one week apart) during the first year following transplantation. The secondary outcome was the time to BK viremia. We created a multivariate model using stepwise forward regression to assess the risk of viremia.

Results
During the study period, there were 1244 transplantations, with 1084 performed between donors and recipients with identical blood types (BT). Grafts were received from a living donor in 787 (63.3%) cases, 158 (98.8%) of which were in the mismatched BT group, and 629 (58%) were in the control group. There were 78 episodes of significant BK viremia within the first year post-transplantation, with 60 (5.5%) occurring in the matched BT recipients and 18 (11.3%) in the mismatched BT group (OR 2.16, p = 0.006). Among grafts from living donors during the first year following transplantation, there were 47 (6%) cases of viremia, with 29 (4.6%) in the matched BT group and 18 (11.4%) in the mismatched BT group (OR 2.22, p = 0.001). Multivariate analysis showed that the risk of BKV viremia in the living donor group increased in the presence of mismatched BT (OR = 2.75, p = 0.002).

Conclusion
The association between donor and recipient BT mismatch and BKV viremia was demonstrated for the first time. Mismatched BT recipients experienced higher rates of BKV viremia compared to identical BT recipients. This might be a preventable risk factor that should guide clinicians in organ procurement.
#1836 Post-transplant evolution of kidney grafts from expanded criteria donors with diabetes
Authors: Singh Arshdeep Singh , Lopez Juan Manuel Cazorla , Fernández Florentino Villanego , Garcia Teresa , Chavez Cristhian Orellana , Vigara Luis Alberto , Alonso Marta , Amaro José Manuel , Castro Pablo , Blanca María Auxiliadora Mazuecos 
Published: May 2024

Abstract

Background and Aims
The increase in the number of potential kidney transplant (KT) recipients has led to efforts to increase the donor pool, including organs from expanded criteria donors (ECD) with diabetes mellitus (DM). However, doubts persist about their viability, especially with DM donors.
Our aim is to analyze the post-transplant evolution of KT patients who have received kidney grafts from ECD with or without DM.

Method
Retrospective observational study of KT who received ECD kidney graft in our center between January 2014 and November 2023. We divided KT patients into two groups based on donor DM; ECD with DM and ECD without DM. We analyzed baseline characteristics and post-KT evolution. Univariate and multivariate statistical analysis was performed using Cox regression (SPSS Statistics 29.0).

Results
During the study period, 161 patients received grafts from ECD at our center. Pre-implant biopsies were performed on all grafts, with 15 discarded due to high histological score. Of these, 13 (86%) were diabetic donors (p &lt; 0.001). The mean age of donors was 66 years, and that of recipients was 61. Forty-three (26%) KT recipients had a diabetic donor. Clinical characteristics of patients are reflected in Table 1.

Conclusion
Donors with DM showed adequate survival in our experience, similar to that of other ECD. This may be due to a more stringent pre-transplant clinical selection or pre-KT histological assessment. The development of new techniques is necessary to more precisely asses the viability of these grafts pre-KT, allowing for an increased utilization.
Effect of Nuts on Anthropometric and Glycemic Indexes and Blood Pressure in Secondary Cardiovascular Prevention: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Bersch-Ferreira Ângela C , Weschenfelder Camila , Waclawovsky Gustavo , da Silva Lucas R , Stein Elana , Machado Rachel H V , Figueiro Mabel F , Suzumura Erica A , Santos Renato H N , Duarte Graziela Biude Silva , Rogero Marcelo M , de Abreu-Silva Erlon O , Cavalcanti Alexandre B , Marcadenti Aline 
Published: May 2024

Abstract

Context
Nut-enriched diets have a positive impact on cardiovascular risk factors, such as body mass, blood pressure, and fasting blood glucose. However, studies in individuals undergoing secondary cardiovascular prevention show controversial results.

Objective
This systematic review with meta-analysis assessed the effect of nut supplementation on anthropometric, glycemic, and blood pressure indices in patients with atherosclerotic cardiovascular disease, as well as the frequency of adverse events.

Data Sources
Six databases were used for the search—PubMed, Cochrane Library, EMBASE, BVS (Biblioteca Virtual da Saude), Web of Science, and ClinicalTrials.gov—until February 2023, with no language restrictions.

Data Extraction
The Cochrane Handbook for Systematic Reviews of Interventions methodology and the PICOS (Population, Intervention, Comparison, Outcome, Setting/design) strategy were used. Seven independent reviewers were involved in data extraction and resolution of disagreements. Certainty of the evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system.

Data Analysis
From 5187 records identified, 6 publications containing data referring to 5 randomized clinical trials (n = 436) were included in the final analyses. The nuts evaluated were almonds, pecans, Brazil nuts, and mixed nuts, with portions that varied between 5 g and 85 g (median: 30 g/day). The intervention period varied between 6 and 12 weeks. The nuts had no effect on fasting glucose and anthropometric indices, although the certainty of the evidence for most of these outcomes was low or very low. They also had no effect on systolic (mean difference [MD]: -1.16 mmHg [95% CI, -5.68 to 3.35], I2 = 0%—moderate certainty of evidence) or diastolic (MD: 0.10 mmHg [95% CI, -2.30 to 2.51], I2 = 0%—high certainty of evidence) blood pressure. It was not possible to aggregate data on adverse events.

Conclusion
Nut supplementation had no effect on blood pressure, fasting glucose, or anthropometric profile in the context of atherosclerotic cardiovascular disease.

Systematic Review Registration
PROSPERO registration no. CRD42020163456.
High Rates of Missed HIV Testing Among Oral PrEP Users in the United States From 2018–2021: A National Assessment on Compliance With HIV Testing Recommendations of the CDC PrEP Guidelines
Authors: Baron Jason , Tchelidze Tamar , LaBrot Benjamin , Yao Joseph , Mayer Kenneth H , Kuritzkes Daniel , Robinson Nicole , Patel Rupa R 
Published: May 2024

Abstract

Background
The US Centers for Disease Control and Prevention recommends HIV testing every 3 months in oral PrEP users. We performed a national assessment of HIV testing compliance among oral PrEP users.

Methods
We analyzed 408 910 PrEP prescriptions issued to 39 809 PrEP users using a national insurance claims database that contained commercial and Medicaid claims. We identified PrEP use based on pharmacy claims and outpatient diagnostic coding. We evaluated the percentage of PrEP prescription refills without HIV testing (identified by CPT codes) within the prior 3, 6, and 12 months using time to event methods. We performed subgroup and multivariate analyses by age, gender, race, insurance type, and geography.

Results
Of 39 809 persons, 36 197 were commercially insured, 3612 were Medicaid-insured, and 96% identified as male; the median age (interquartile range) was 34 (29–44) years, and the Medicaid-insured PrEP users were 24% Black/African American, 44% White, and 9% Hispanic/Latinx. Within the prior 3, 6, and 12 months, respectively, the percentage of PrEP prescription fills in individuals without HIV Ag/Ab testing was 34.3% (95% CI, 34.2%–34.5%), 23.8% (95% CI, 23.7%–23.9%), and 16.6% (95% CI, 16.4%–16.7%), and the percentage without any type of HIV test was 25.8% (95% CI, 25.6%–25.9%), 14.6% (95% CI, 14.5%–14.7%), and 7.8% (95% CI, 7.7%–7.9%).

Conclusions
Approximately 1 in 3 oral PrEP prescriptions were filled in persons who had not received an HIV Ag/Ab test within the prior 3 months, with evidence of health disparities. These findings inform clinical PrEP monitoring efforts and compliance with national HIV testing guidance to monitor PrEP users.
Forgiveness and the Modern Constitution: Derrida’s Perjury & Pardon
Authors: de Ville Jacques 
Published: May 2024

Abstract
The recently published two volumes of Derrida’s Perjury & Pardon seminars are interesting from a legal perspective, among others, because of Derrida’s comments there on the preamble and certain sections of the South African Constitution. The present article enquires specifically into the implications of Derrida’s analysis in the Perjury & Pardon seminars for constitutional interpretation, more specifically, by seeking answers to the question what it means to confess or to seek forgiveness for past crimes, as well as to refer to God in a constitution. With reference to Derrida’s seminars, it is contended that such a confession or request for forgiveness should be read as not only relating to determined crimes, but also to the unforgiveable crime of being-there, for existence. It is further contended that the reference to God in a constitution is to be read as pointing to what Derrida refers to as ‘the impossible’, that is, to impossible grace, unconditional forgiveness. In conclusion, it is contended that the modern constitution per definition includes such a confession or request for forgiveness, as well as a trace of the impossible, the latter which provides an indication of the scope of state responsibility.
Introduction
Authors: Kane Brian 
Published: May 2024

Abstract
Standards are crucial to the performance of jazz, but they present a philosophical problem that has not been adequately solved. Undergoing constant transformation, substitution, and alteration, they still manage to preserve their identity across a wide variety of performances. In the introduction to this book, the philosophical problem of the standard is described. In addition, the basic layout of the book’s argument is presented: Part I of the book treats of the philosophical issues concerning the standard as a musical work; Part II considers the social and historical conditions by which the phenomenon of the standard emerged. While one part considers the ontology of standards, the other part considers the auditory culture of the standard. But the two parts mutually support one another. The reader is encouraged to understand jazz standards as a case study in the mutually constitutive relationship of ontology and auditory culture.
Nomination
Authors: Kane Brian 
Published: May 2024

Abstract
This chapter introduces the concept of musical nomination, the second of two key processes involved in the emergence of a standard from a network of musical performances. Nomination is the act of giving a work or a performance a name. Names create associations between performances, placing two distinct performances into a single network. Unlike musical replications, they make associations without any appeal to morphology. By considering replication and nomination in tandem, this chapter offers an analytic and philosophical framework for discussing the identity and individuation of musical works. The utility of this framework is in its ability to account for ambiguous cases such as contrafacts and revisions. Through two case studies—one on Charlie Parker’s performances and contrafacts of “Embraceable You,” and the other on John Coltrane’s “Impressions”—this chapter demonstrates that consideration of both replication nomination is required when accounting for the ontology of jazz standards.
Conflict
Authors: Schofield John 
Published: May 2024

Abstract
Chapter 7 discusses conflict and the wicked implications that this has for those affected by it. It emphasises the dilemma of the need to address post-war reconstruction versus the need to support people in other ways, particularly those displaced by conflict. The chapter discusses how archaeologists are well placed to deal with heritage related to conflict because of their deep-time perspective and the social emphasis that their work entails. The chapter defines types of conflict and how heritage organizations have engaged with its implications. The work of scholars who have addressed conflict as a wicked problem is discussed along with examples of ways that conflict sites have been recognized as heritage sites. Examples are presented of small wins whereby archaeological or heritage projects have helpfully engaged with the repercussions of conflicts in a variety of ways. The closing example concerns refugees and how archaeologists have engaged with these communities to support their well-being.
The World’s Evils Are Logically Incompatible with God’s Existence
Authors: Sterba James 
Published: May 2024

Abstract
Sterba begins with a fourfold classification of all the goods that God could provide and sets out three necessary moral prevention requirements that are exceptionless minimal components of the Pauline Principle. He applies these requirements to his classification of the goods that God could provide. He concludes that any God that exists would have to be in widespread violation of these moral evil prevention requirements and so could not be the God of traditional theism. The God of traditional theism should have prevented the horrendous evil consequences of immoral actions, but not other evil consequences for which we would have complete responsibility so as not to be in a moral kindergarten. Sterba also discusses natural evil, distinguishes between an ethics before creation and an ethics after creation, and considers the possibility of a God who is good but not morally good or is limited with respect to goodness and/or power.
Response to Swinburne
Authors: Sterba James 
Published: May 2024

Abstract
Sterba first briefly restates his argument that the God of traditional theism is logically incompatible with all the evil in the world. He responds to Swinburne’s objections to that argument, including the two counterexamples that Swinburne raises to the premises of that argument. Sterba then turns to a consideration of Swinburne’s own argument in defence of the God of traditional theism and shows that given Swinburne’s own normative premises, the God of traditional theism is logically incompatible with all the evil in the world. Finally, Sterba claims that it was only because he was working in moral and political philosophy that he was able to come up with exceptionless, minimal components of the Pauline Principle that are necessary requirements of morality and utilize categories from political philosophy to consider all the goods with which God could provide us in order to construct the Mackie-style argument that he defends in this book.
Family-centred music therapy in the neonatal intensive care unit (NICU)
Authors: Ettenberger Mark , Haslbeck Friederike , Ullsten Alexandra 
Published: May 2024

Abstract
Chapter 9 introduces and discusses family-centred music therapy in the neonatal intensive care unit (NICU). Having an infant hospitalised can be a stressful and traumatic life event for many parents, including impaired parental mental health and difficulties in continuing the emerging parent–infant relationship. Family-centred music therapy offers individually tailored, evidence-based, and parent-led musical experiences in the context of a therapeutic relationship. The chapter explores the rationale of family-centred music therapy in the NICU, its objectives, results from current and past research, and some music therapeutic experiences drawing on the authors’ work in Latin America, Central Europe, and Scandinavia. The chapter aims to provide readers with knowledge about the therapeutic use of music in the NICU and to make accessible education strategies for parents and staff regarding the application of music during and after infant hospitalisation.
Group music-making with families affected by Zika virus in Brazil
Authors: Lisboa Tânia , Santiago Diana , Fonte Vera , Shaughnessy Caitlin , Perkins Rosie 
Published: May 2024

Abstract
Chapter 12 explores how music-making can promote wellbeing for mothers of children affected by the Zika virus (ZIKV) in Brazil. An outbreak of ZIKV in 2015 had profound effects on children and families in the Northeast of Brazil, where hundreds of children exposed to the virus in utero were born with severe microcephaly, developmental delays, physical disabilities, and special educational needs, now classified under the term congenital Zika syndrome (CZS). This chapter introduces a six-week programme of group online music-making that was developed and run for mothers and their children with CZS, alongside interviews and video observations of music sessions. The learnings of the project are explored through two exploratory vignettes, highlighting the important role of music in everyday life and its potential to support some of the psychosocial needs of families affected by CZS.
Activism and the Shaping of Sexual Politics
Authors: Rusterholz Caroline 
Published: May 2024

Abstract
Chapter 3 focuses on the way that Brook members shaped reproductive politics, the alliances they formed, and the lobby strategies they developed to expand the provision of contraception for young people over time. The chapter focuses on the microcosm of advocacy for contraception, which saw Brook members individuals navigating between different health charities and organizations such as the Family Planning Association, the Abortion Law Reform Association, the Birth Control Trust, and Pregnancy Advisory Services. It then moves to address the ways Brook member dealt with issues around fundings. Finally, it explores the various key sexual health policies that Brook fought or helped to implement over the years.