bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social connections and information leakage: Evidence from target stock price run‐up in takeovers
Authors: Hasan Iftekhar , Tong Lin , Yan An 
Published: June 2024

AbstractDoes information leakage in a target's social networks increase its stock price prior to a merger announcement? Evidence reveals that a target with more social connections indeed experiences a higher pre‐announcement price run‐up. This effect does not exist during or after the merger announcement, or in windows ending two months before the announcement. It is more pronounced among targets with severe asymmetric information, and weaker when the information about the upcoming merger is publicly available prior to the announcement. It is also weaker in expedited deals such as tender offers.
Microencapsulation of Rosa roxburghiiTratt with characterization of the powder and nutritional potential
Authors: Tang Jun , Gao Xuan , Yousaf Muhammad , Liu Dong‐Mei 
Published: June 2024

AbstractThe aim of this study was to investigate the freeze‐drying process of Rosa roxburghii Tratt powder and evaluate the bioactive compound and physicochemical properties of the powder produced under optimal conditions. The external properties of the three different encapsulating agents were compared. Based on this, we selected the appropriate enzyme and encapsulating agent and performed response surface process optimization. The thermodynamic analysis, particle size, ATR‐FTIR spectra, X‐ray diffraction, antioxidant properties, and inhibitory activity against pancreatic lipase of R. roxburghii Tratt powders were characterized using super‐fine grinding powder as a control. The results showed that vacuum freeze‐dried powder exhibited 78.05% ± 6.24% scavenging rate of DPPH at 0.5 mg/mL and the inhibition rate of pancreatic lipase at 10 mg/mL was 74.53% ± 0.87%, and possessed significant antioxidant and hypolipidemic activities in vitro. This study provides a reference to the application of R. roxburghii Tratt powder in food and agriculture.Practical applicationsAs Rosa roxburghii Tratt juice is not easy to preserve and components with high nutritional value are easily lost during storage or transport, drying the fresh fruit is often used to extend shelf life and develop new products. Through the comparison and application of the encapsulating agents and enzymes, we successfully screened the suitable encapsulating agent and enzyme for the microencapsulation of R. roxburghii Tratt. After process optimization, powder characterization, antioxidant, and pancreatic lipase inhibition analyses, it was demonstrated that the R. roxburghii Tratt powder has a microencapsulation effect, a certain degree of crystallinity, exhibits excellent nutritional potential, and is stable to heat. This study provides a reference to the application of R. roxburghii Tratt powder in food and agriculture.
Association between gut microbiota and acute pancreatitis: a bidirectional Mendelian randomization study
Authors: Zhou Feng , Liu Yang , Shi Yanqing , Wu Nanzhen , Xie Yong , Zhou Xiaojiang 
Published: June 2024

AbstractBackground and AimThe dysbiosis of gut microbiota has been reported in acute pancreatitis. However, the direction and magnitude between host microbiota and pancreas remains to be established. This study investigated the association between gut microbiota and acute pancreatitis using Mendelian randomization (MR) methods.MethodsSummary statistics of gut microbiota abundance and acute pancreatitis were extracted from genome‐wide association studies (GWAS). The two‐sample bidirectional MR design was employed to assess genetic association between the microbiota and pancreatitis, followed by a comprehensive sensitivity analysis to verify the robustness of the results.ResultsSeven microbiota taxa have been identified as significantly associated with the development of pancreatitis. Host genetic‐driven order Bacteroidales and class Bacteroidia are associated with an increased risk of pancreatitis. The genera Coprococcus and Eubacterium fissicatena group also exhibit a positive effect on the development of pancreatitis, while the genera Prevotella, Ruminiclostridium, and Ruminococcaceae act as protective factors against pancreatitis. In contrast, acute pancreatitis was positively correlated with phylum Proteobacteria and genus Lachnospiraceae and negatively correlated with genus Holdemania.ConclusionsThe bidirectional relationship between gut microbiota and acute pancreatitis suggests a critical role for host‐microbiota crosstalk in the development of the disease. Targeted modulation of specific gut microbiota enables the prevention and treatment of acute pancreatitis.
α1‐COP modulates plasmodesmata function through sphingolipid enzyme regulation
Authors: Iswanto Arya Bagus Boedi , Vu Minh Huy , Shon Jong Cheol , Kumar Ritesh , Wu Shuwei , Kang Hobin , Kim Da‐Ran , Son Geon Hui , Kim Woe Yoen , Kwak Youn‐Sig , Liu Kwang Hyeon , Kim Sang Hee , Kim Jae‐Yean 
Published: June 2024

ABSTRACTCallose, a β‐1,3‐glucan plant cell wall polymer, regulates symplasmic channel size at plasmodesmata (PD) and plays a crucial role in a variety of plant processes. However, elucidating the molecular mechanism of PD callose homeostasis is limited. We screened and identified an Arabidopsis mutant plant with excessive callose deposition at PD and found that the mutated gene was α1‐COP, a member of the coat protein I (COPI) coatomer complex. We report that loss of function of α1‐COP elevates the callose accumulation at PD by affecting subcellular protein localization of callose degradation enzyme PdBG2. This process is linked to the functions of ERH1, an inositol phosphoryl ceramide synthase, and glucosylceramide synthase through physical interactions with the α1‐COP protein. Additionally, the loss of function of α1‐COP alters the subcellular localization of ERH1 and GCS proteins, resulting in a reduction of GlcCers and GlcHCers molecules, which are key sphingolipid (SL) species for lipid raft formation. Our findings suggest that α1‐COP protein, together with SL modifiers controlling lipid raft compositions, regulates the subcellular localization of GPI‐anchored PDBG2 proteins, and hence the callose turnover at PD and symplasmic movement of biomolecules. Our findings provide the first key clue to link the COPI‐mediated intracellular trafficking pathway to the callose‐mediated intercellular signaling pathway through PD.
The regulatory mechanism of rapid lignification for timely anther dehiscence
Authors: Xue Jing‐Shi , Feng Yi‐Feng , Zhang Ming‐Qi , Xu Qin‐Lin , Xu Ya‐Min , Shi Jun‐Qin , Liu Li‐Fang , Wu Xiao‐Feng , Wang Shui , Yang Zhong‐Nan 
Published: June 2024

ABSTRACTAnther dehiscence is a crucial event in plant reproduction, tightly regulated and dependent on the lignification of the anther endothecium. In this study, we investigated the rapid lignification process that ensures timely anther dehiscence in Arabidopsis. Our findings reveal that endothecium lignification can be divided into two distinct phases. During Phase I, lignin precursors are synthesized without polymerization, while Phase II involves simultaneous synthesis of lignin precursors and polymerization. The transcription factors MYB26, NST1/2, and ARF17 specifically regulate the pathway responsible for the synthesis and polymerization of lignin monomers in Phase II. MYB26‐NST1/2 is the key regulatory pathway responsible for endothecium lignification, while ARF17 facilitates this process by interacting with MYB26. Interestingly, our results demonstrate that the lignification of the endothecium, which occurs within approximately 26 h, is much faster than that of the vascular tissue. These findings provide valuable insights into the regulation mechanism of rapid lignification in the endothecium, which enables timely anther dehiscence and successful pollen release during plant reproduction.
Applying the Rupture Resolution Rating System to emotion‐focused couple therapy
Authors: Sherlow‐Levin Avital , Shahar Ben , Goldman Rhonda , Bar‐Kalifa Eran 
Published: June 2024

AbstractAlliance ruptures and their repair are robustly associated with outcomes in individual therapy. Little is known about these processes in couple therapy, despite the acknowledged challenges of nurturing the alliance when working with two parties in conflict. One factor contributing to this gap in the literature is the lack of an instrument to capture ruptures and repair in couple therapy. We adapted the Rupture Resolution Rating System (3RS) to identify ruptures and repairs in couple therapy at the within‐system (between the two partners) and the between‐system (between each partner and the therapist) levels. Sessions from one couple with good outcome and one couple with poor outcome were coded. Couples were in therapy to deal with emotional injury. Rupture‐repair events in both the within‐system and between‐system were common. The couple with the poor outcome showed greater levels of rupture with the therapist. The injured partners (vs. injurer partners) demonstrated higher frequencies of ruptures.
Predicting sepsis at emergency department triage: Implementing clinical and laboratory markers within the first nursing assessment to enhance diagnostic accuracy
Authors: Sisto Ugo Giulio , Di Bella Stefano , Porta Elisa , Franzoi Giorgia , Cominotto Franco , Guzzardi Elena , Artusi Nicola , Giudice Caterina Anna , Dal Bo Eugenia , Collot Nicholas , Sirianni Francesca , Russo Savino , Sanson Gianfranco 
Published: June 2024

AbstractBackgroundEarly identification of sepsis in the emergency department (ED) triage is both valuable and challenging. Numerous studies have endeavored to pinpoint clinical and biochemical criteria to assist clinicians in the prompt diagnosis of sepsis, but few studies have assessed the efficacy of these criteria in the ED triage setting. The aim of the study was to explore the accuracy of clinical and laboratory markers evaluated at the triage level in identifying patients with sepsis.MethodsA prospective study was conducted in a large academic urban hospital, implementing a triage protocol aimed at early identification of septic patients based on clinical and laboratory markers. A multidisciplinary panel of experts reviewed cases to ensure accurate identification of septic patients. Variables analyzed included: Charlson comorbidity index, mean arterial pressure (MAP), partial pressure of carbon dioxide (PetCO2), white cell count, eosinophil count, C‐reactive protein to albumin ratio, procalcitonin, and lactate.ResultsA total of 235 patients were included. Multivariable analysis identified procalcitonin ≥1 ng/mL (OR 5.2; p < 0.001); CRP‐to‐albumin ratio ≥32 (OR 6.6; p < 0.001); PetCO2 ≤ 28 mmHg (OR 2.7; p = 0.031), and MAP <85 mmHg (OR 7.5; p < 0.001) as independent predictors for sepsis. MAP ≥85 mmHg, CRP/albumin ratio <32, and procalcitonin <1 ng/mL demonstrated negative predictive values for sepsis of 90%, 89%, and 88%, respectively.ConclusionsOur study underscores the significance of procalcitonin and mean arterial pressure, while introducing CRP/albumin ratio and PetCO2 as important variables to consider in the very initial assessment of patients with suspected sepsis in the ED.Clinical Relevance

Early identification of sepsis since the emergency department (ED) triage is challenging

Implementing the ED triage protocol with simple clinical and laboratory markers allows to recognize patients with sepsis with a very good discriminatory power (AUC 0.88)
A scoping review of hospital to home transitional care programmes for stroke survivors
Authors: Xu Xuewei , Chen Huijie , Xu Dandan , Tan Fengying , Li Xiaohan 
Published: June 2024

AbstractAimThe study was aimed at exploring the current scope of hospital to home transitional care programmes for stroke survivors.BackgroundStroke survivors face the dilemma of solving many complex problems that leave survivors at high risk for readmission as they discharge from hospital. The transitional care model has proved to be effective in reducing readmissions and mortality, thereby improving health outcomes and enhancing patient satisfaction for survivors with stroke.DesignA scoping review.MethodsConducted in accordance with the Joanna Briggs Institute (JBI) Methodology for Scoping Reviews.Data SourcesA comprehensive search was conducted in nine databases, including PubMed, Web of Science, Cochrane Library, EMBASE, CINAHL, Medline, China Knowledge Net‐work, Wanfang Database and China Biomedical Literature Database (SinoMed) from January 2014 to June 2023.ResultsTitle and abstract screening was performed on 10,171 articles resulting in 287 articles for full‐text screening. Full‐text screening yielded 49 articles that met inclusion criteria.ConclusionThis study identified transitional care programmes for stroke survivors, as well as areas for future consideration to be explored in more depth to help improve transitional care for stroke survivors as they transition from hospital to home.Implications for the Profession and/or Patient CareThis study demonstrates that multidisciplinary collaboration becomes an integral part of the transitional care model for stroke survivors, which provides comprehensive and precise medical care to them.Reporting MethodPRISMA checklist for scoping reviews.Patient and Public ContributionNo patient or public contribution was part of this study.
Patients in isolation, their physical, environmental and mental health: An exploratory study
Authors: Digby Robin , Kramer Sharon , Yuan Vicky , Ozavci Guncag , Bucknall Tracey K. 
Published: June 2024

AbstractBackgroundStrict patient isolation in hospital is associated with adverse health outcomes. However, there is a lack of high‐quality evidence for effective interventions to improve safety and quality of care for these patients.AimsTo identify patient reported areas for improvement in the care of patients in hospital isolation and to determine the feasibility of collecting patient reported outcomes using validated tools.MethodsDesignAn exploratory mixed methods study.SettingA major metropolitan teaching hospital in Melbourne, Australia.ParticipantsPatients in hospital isolation for transmissible infections.Data collectionData were collected by (1) phone interviews with patients in isolation and (2) seven validated measurement tools to assess cognition, loneliness, nutritional status, quality of life, anxiety and depression and physical activity. Data were collected between September and December 2021.Data analysisInterviews were transcribed and analysed using thematic analysis. Quantitative data were analysed descriptively including participant characteristics and outcome data.ResultsParticipants identified areas for improvement including activities to decrease boredom, more contact with staff to mitigate loneliness and increase comfort care, and formalised communication about clinical treatment and discharge plan. Patients with gastrointestinal symptoms were happier to be alone. There were operational challenges within the health service including delays and miscommunication. Only 70% of the participants completed all questionnaires.ConclusionThis study identified areas for improvement in care of patients in isolation and demonstrated that collecting patient reported outcomes using validated tools was feasible. The results of this research will inform development of an intervention to manage adverse effects.Implications for the Profession and/or Patient CarePatients in hospital isolation require additional consideration to ensure that their needs are met to avoid adverse outcomes. The patient experience and comfort can be negatively affected when fundamental care is lacking.Reporting Method (EQUATOR)EQUATOR guidelines for Mixed Methods Reporting in Rehabilitation & Health Sciences (MMR‐RHS).Patient or Public ContributionThirteen patients in hospital isolation agreed to participate in this study, sharing their experiences through interviews and assessment.
Becoming whole again—Caring for the self in chronic illness—A narrative review of qualitative empirical studies
Authors: Hajdarevic Senada , Norberg Astrid , Lundman Berit , Hörnsten Åsa 
Published: June 2024

AbstractAim and ObjectivesTo explore how chronic illness transforms the self when living with and managing chronic illness and what this means for their self and identity. We also discuss how people with chronic conditions could be supported by healthcare professionals to manage illness in daily life.BackgroundSelf‐management recommendations from health care are commonly based on a biomedical understanding of the disease. People's experiences of how a condition affects them and adequate support are crucial for their outcomes in daily self‐management.DesignA narrative review.MethodsA systematic search was undertaken during January 2021 across the databases MEDLINE, CINAHL, PsycINFO, Soc INDEX and Philosopher's Index. A quality appraisal of articles was performed. Our analysis was inspired by qualitative content analysis. The PRISMA Checklist 2020/EQUATOR guidelines was used to report the study.ResultsTwenty‐eight peer‐reviewed qualitative empirical articles focusing on self in a variety of chronic illnesses with relevance to nursing published from January 2010 to December 2020 were included. The main theme, Developing from an uncertain existence to meaning and wholeness, was built up by the five themes: Walking on an unstable ground; Being stalemated; Being involved with others for better or worse; Searching for meaning; and lastly, Modifying self and integrating a new way of living.ConclusionsThe results illuminate experiences that seldom are prioritized but need to be addressed by health professionals. Such experiences are oriented more towards the existential self rather than medical issues, why it is important to go beyond the medical lens.Relevance to Clinical PracticeThis is important knowledge for nurses aiming to support people with chronic illnesses. Nurses supporting people in self‐management need to be aware that by teaching and encouraging people to revise their daily habits, they also work on the boundaries of their self‐concept.Patient or Public ContributionNo patient or public contribution.
Understanding market sentiment analysis: A survey
Authors: Heydarian Peyman , Bifet Albert , Corbet Shaen 
Published: June 2024

AbstractMarket sentiment analysis (MSA) has evolved significantly over nearly four decades, growing in relevance and application in economics and finance. This paper extensively reviews MSA, encompassing methodologies ranging from lexicon‐based techniques to traditional Machine Learning (ML), Deep Learning (DL), and hybrid approaches. Emphasizing the transition from rudimentary word counters to sophisticated feature extraction from diverse sources such as news, social media, and share prices, the study presents an updated state‐of‐the‐art review of sentiment analysis. Furthermore, using network analysis, a bibliometric and scientometric lens is applied to map the expanding footprint of sentiment research within economics and finance, revealing key trends, dominant research hubs, and potential areas for interdisciplinary collaboration. This exploration consolidates the foundational and emerging methods in MSA and underscores its dynamic interplay with global financial ecosystems and the imperative for future integrative research trajectories.
Kierkegaard, Social Media, and Despair
Authors: Robinson Tekoa 
Published: June 2024

ABSTRACTThis essay offers a Kierkegaardian analysis of and response to the harmful effects of destabilization that can be caused by engaging with certain technological media. It argues that the intellectual technological ethic that is at work in social media platforms reflects two types of despair discussed in Søren Kierkegaard's Sickness Unto Death. It advises using a Kierkegaard‐inspired Socratic rhetorical strategy of communication that ironically employs technology for depicting this despair and awakening individuals to its presence in their lives. Moreover, this essay suggests that the edifying themes of “misery” and “guilt” can be communicated indirectly and thereby offer one intervention that could possibly help the current technological age move from the immediate aesthetic sphere of existence to the religious sphere. Considering the important role of upbuilding in Kierkegaard's oeuvre, the final portion explores how even someone who does not identify with a religious tradition or community may encounter what Kierkegaard terms the paradox of the eternal in time in ways that foster the development of authentic selfhood.
Quantifying the impacts of climate shocks in commercial real estate markets
Authors: Holtermans Rogier , Niu Dongxiao , Zheng Siqi 
Published: June 2024

AbstractThis study investigates the capitalization of climate shocks in commercial real estate owned and operated by professional investors. We focus on Hurricanes Harvey and Sandy to quantify the price impacts of climate shocks on commercial buildings in Texas and New York. We find clear evidence of a decline in transaction prices in hurricane‐damaged areas after the hurricanes made landfall, compared to unaffected areas. We also observe that the “new news” about climate risk is significantly priced in both states—assets in locations outside the FEMA floodplain (with a lower prior perception of flood risk) that were inundated by the hurricanes experienced larger price discounts, indicating that actual flooding updates investors' perception of flood risk. Moreover, we find that the hurricane discount is more pronounced among buyers with more transaction experience. The transaction price discount also increases with higher climate change beliefs in the local market and among investors. Our findings underline the role of information provision and environmental awareness in the materialization of climate risks' impact on commercial real estate values.
Pop‐Up Safety Town: Leveling the Playing Field for Children in Underserved Communities Through Injury Prevention Education
Authors: Boeke Sarah , Kim Erin , Ryan Charlotte , Hashikawa Andrew , Wendt Wendi‐Jo 
Published: June 2024

ABSTRACTBACKGROUNDUnintentional injuries are the leading cause of morbidity and mortality among children and adolescents in the United States. Traditional injury education interventions for children often are inaccessible due to cost and logistics in underserved communities, exacerbating injury disparities. A new approach is needed to close this gap for families with preschool children.CONTRIBUTIONS TO THEORYCollaborating with Head Start preschools optimizes engagement and accessibility to families in underserved communities. Involving caregivers and community organizations addresses the limitations of conventional interventions and community‐specific injury prevention concerns.IMPLICATIONS FOR SCHOOL HEALTH POLICY, PRACTICE, AND EQUITYPop‐up Safety Town offers a more affordable model for injury prevention education, particularly in underserved regions. The model's approach, using adaptable education, mobile and reusable materials, and volunteer staffing, offers greater potential for achieving sustainable impact in these underserved communities.CONCLUSIONSPop‐up Safety Town presents a novel upstream solution to address disparities in injury prevention education in underserved communities.