bluuebunny/crossref_metadata_2025_split huggingface dataset:
A germline PAF1 paralog complex ensures cell type-specific gene expression
Authors: Vilstrup Astrid Pold , Gupta Archica , Rasmussen Anna Jon , Ebert Anja , Riedelbauch Sebastian , Lukassen Marie Vestergaard , Hayashi Rippei , Andersen Peter 
Published: May 2024

ABSTRACTAnimal germline development and fertility rely on paralogs of general transcription factors that recruit RNA polymerase II to ensure cell type-specific gene expression. It remains unclear whether gene expression processes downstream of such paralog-based transcription is distinct from that of canonical RNA polymerase II genes. InDrosophila, the testis-specific TBP-associated factors (tTAFs) activate over a thousand spermatocyte-specific gene promoters to enable meiosis and germ cell differentiation. Here, we show that efficient termination of tTAF-activated transcription relies on testis-specific paralogs of canonical Polymerase Associated Factor 1 Complex (PAF1C) proteins, which form a testis-specific PAF1C (tPAF). Consequently, tPAF mutants cause aberrant expression of hundreds of downstream genes due to read-in transcription. Furthermore, tPAF facilitates expression of Y-linked male fertility factor genes, and thus broadly maintains spermatocyte-specific gene expression. Consistently, tPAF is required for the segregation of meiotic chromosomes and male fertility. Supported by comparativein vivoprotein interaction assays, we provide a mechanistic model for the functional divergence of tPAF and PAF1C and for transcription termination as a developmentally regulated process required for cell type-specific gene expression.
Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory
Authors: Watson Jake F. , Vargas-Barroso Victor , Morse-Mora Rebecca J. , Navas-Olive Andrea , Tavakoli Mojtaba R. , Danzl Johann G. , Tomschik Matthias , Rössler Karl , Jonas Peter 
Published: May 2024

AbstractThe human brain has remarkable computational power. It generates sophisticated behavioral sequences, stores engrams over an individual’s lifetime, and produces higher cognitive functions up to the level of consciousness. However, so little of our neuroscience knowledge covers the human brain, and it remains unknown whether this organ is truly unique, or is a scaled version of the extensively studied rodent brain. To address this fundamental question, we determined the cellular, synaptic, and connectivity rules of the hippocampal CA3 recurrent circuit using multicellular patch clamp-recording. This circuit is the largest autoassociative network in the brain, and plays a key role in memory and higher-order computations such as pattern separation and pattern completion. We demonstrate that human hippocampal CA3 employs sparse connectivity, in stark contrast to neocortical recurrent networks. Connectivity sparsifies from rodents to humans, providing a circuit architecture that maximizes associational power. Unitary synaptic events at human CA3–CA3 synapses showed both distinct species-specific and circuit-dependent properties, with high reliability, unique amplitude precision, and long integration times. We also identify differential scaling rules between hippocampal pathways from rodents to humans, with a moderate increase in the convergence of CA3 inputs per cell, but a marked increase in human mossy fiber innervation. Anatomically guided full-scale modeling suggests that the human brain’s sparse connectivity, expanded neuronal number, and reliable synaptic signaling combine to enhance the associative memory storage capacity of CA3. Together, our results reveal unique rules of connectivity and synaptic signaling in the human hippocampus, demonstrating the absolute necessity of human brain research and beginning to unravel the remarkable performance of our autoassociative memory circuits.
Constructing an accountability regime for proxy advisors: an organizational roles perspective
Authors: Lambert Damien , Wiegmann Leona 
Published: May 2024

PurposeThis study investigates how the interrelated elements of organizational roles – activities, motives, resources and relationships – are mobilized to construct a code of conduct for the proxy advisory (PA) industry in Europe.Design/methodology/approachThis qualitative study uses archival documents from three consecutive regulatory consultations and 16 interviews with key stakeholders. It analyzes how different stakeholder groups (i.e. PA firms, investors, issuers and the regulator) perceive and mobilize the elements of PA firms’ role to construct the accountability regime’s boundaries (accountability problem and action, and users and providers of accounts).FindingsThis study shows how PA firms, investors, issuers and the regulator refer to the perceived motives behind PA firms’ activities to construct an accountability problem. The regulator accepted the motives of an information intermediary for PA firms’ role and required PA firms to develop a corresponding accountability action: a code of conduct. PA firms involved in developing the code of conduct formalized who is accountable to whom by aligning this accepted motive with their activities, relationships, and resources into a common role.Originality/valueThe study highlights how aligning role elements to reflect PA firms’ common roles enables the construction of an accountability regime that stakeholders accept as a means of regulation. Analyzing the role elements offers insights into the development and functioning of accountability regimes that rely on self-regulation. We also highlight the role of smaller regional firms in helping shape transnational accountability regimes.
Stored collections of museums: an overview of how visible storage makes them accessible
Authors: Corona Lara 
Published: May 2024

Purpose
This study aims to provide an overview of the dimension of stored collections displayed in visible storage and to indicate the main factors which hinder their accessibility.

Design/methodology/approach
This study is based on quantitative analysis: a survey was conducted through the offices of International Council of Museums and direct invitations to 2,558 museums located worldwide.

Findings
The study estimated 32% on average the share of stored collections displayed in visible storage. The analysis provides a picture of how many stored items are made accessible in visible storage across the continents, according to the collection’s type and size and the museums’ legal status. In addition, several aspects of visible storage are investigated to highlight whether or not it truly enables museums to achieve accessibility of their stored collections and which factors might hinder the accessibility. Amid them, the foremost factors involve the inadequacy of resources, such as the lack of staff (71%) and poor budget (68%). Because of it, museums are prone to setting up offsite storage (37%), often 16 km far from the city centre, thereby questioning the concept of accessibility itself.

Research limitations/implications
One major limitation of this study is that it does not consider people’s standpoints. Therefore, the author recommends that future studies focus on what people opine on visible storage, such as their appreciation of the display format, the behind-the-scenes, their need for interpretation and the degree of satisfaction with their information needs, as well as their perception of the size of stored collections.

Practical implications
These findings suggest that museums could take action in areas whereby the data demonstrated weaknesses in terms of accessibility. For instance, museums could set up a shuttle service or arrange public transportation service to allow people to visit offsite storage. Additionally, financial accessibility might be achieved by not charging some groups (elderly, students, etc.).

Social implications
The topic of stored collections and their accessibility has crucial social implications because not displaying collections triggers inequality amid social groups of excluded people and a small elite.

Originality/value
This study focuses on visible storage as a possible solution to enhance the accessibility of collections and indicates to what extent visible storage provides this accessibility. On the contrary, previous research did not estimate how much visible storage impacts the accessibility of stored collections.
The effect of AI-enabled HRM dimensions on employee engagement and sustainable organisational performance: fusion skills as a moderator
Authors: Jangbahadur Uttara , Ahlawat Sakshi , Rozera Prinkle , Gupta Neha 
Published: May 2024

PurposeThis paper examines and empirically validates the artificial intelligence-enabled human resource management (AI-enabled HRM) dimensions and sustainable organisational performance (SOP) relationship. It also examines the mediation and moderation of employee engagement (EE) and fusion skills (FS).Design/methodology/approachThe indirect effects of AI-enabled HRM dimensions on SOP were found using structural equation modelling (SEM), bootstrapping and FS’s moderation effect by AMOS 22.FindingsResults showed that AI-enabled HRM dimensions indirectly affected SOP through EE as a full and partial mediator with no moderation effects of FS.Originality/valueThis is the first study to link AI-enabled HRM dimensions, EE and SOP and determine how FS moderates EE and SOP.
Whistleblowing and interpretation, addressing organizational challenges: a conceptual reflection from Nigeria
Authors: Ufua Daniel E. , Butt Fawwad M. , Al-Faryan Mamdouh Abdulaziz Saleh 
Published: May 2024

PurposeThis study aims to explore the effect of whistleblowing and interpretation among practitioners in the Nigerian economy. The research puts a premium on understanding the relevance and critical issues in its practices and developing an improved model for the effective practice of whistleblowing and interpretation in Nigeria.Design/methodology/approachThis study adopted a conceptual approach, relying on extant literature to understand the management of whistleblowing incidents and identify the managers’ and other stakeholders’ responsibility in the whistleblowing process. It applied systems dynamics conceptual modelling and presented an improvement approach to addressing the complexities associated with whistleblowing and interpretation among Nigerian organizations.FindingsThis study contributed to the extant literature by developing a model for proper management of whistleblowing in the Nigerian context and enhancing the robust practice of whistleblowing and interpretation in Nigeria. The findings highlighted critical factors such as managers’ skills development, legal system support, institutional stakeholders’ function and ethical balance as key factors to effective whistleblowing management and interpretation. This implies that the act of identifying and developing responses to an emerging case of whistleblowing requires a process of developing underpinning assumptions, engagement and consideration of stakeholders’ interests while driving the sustenance of organizational focus.Originality/valueThis study emphasized the departure from absolute best practice to developing idea approaches that reflect stakeholders’ interests and the context of whistleblowing and interpretation. While the study acknowledges limitations in the sole focus on the Nigerian private sector and the Nigerian economic background, it recommends further exploration of whistleblowing and its interpretation on a comparative approach, to improving the current understanding of the topic.
Financial well-being of internal migrant labours: the role of financial socialisation, financial knowledge and financial behaviour
Authors: Gafoor Abdul , Amilan S , Patel Versha 
Published: May 2024

PurposeThe primary purpose of the research is to examine the impact of financial socialisation (FS) on the financial well-being (FWB) of unskilled internal migrant labourers, particularly focusing on the intervening roles of financial knowledge (FK) and financial behaviour (FB).Design/methodology/approachUsing a cross-sectional research design, primary data from 269 unskilled internal migrant labourers were collected, applying the purposive sampling method. Using the data, the direct and mediated effects are examined through a three-path mediation model with structural equation modelling (SEM).FindingsDirect relationship analysis of FS on FWB exhibits an insignificant relationship, and FK also does not mediate the relationship; instead, FB acts as a potent mediator in both relationships.Research limitations/implicationsThe study enriches existing literature as it contributes to understanding the FWB of internal migrant labour, highlighting the pivotal role of FS and FB. Further, it provides insights for policymakers to enhance FWB through targeted interventions and inclusive policies, promoting social inclusion, economic empowerment and inclusive development.Originality/valueDespite the significant economic role of unskilled internal migrant labours, studies have not focused on their FWB. Hence, the study delves into their FWB through FS directly as well as indirectly using a three-path mediation model for achieving sustainable development.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/IJSE-01-2024-0044
Big data analytics usage in the banking industry in Tanzania: does perceived risk play a moderating role on the technological factors
Authors: Mwemezi Justus , Mandari Herman 
Published: May 2024

PurposeThe main purpose of this paper is to examine the adoption of big data analytics (BDA) in the Tanzania banking industry by investigating the influence of technological, environmental and organizational (TOE) factors while exploring the moderating role of perceived risk (PR).Design/methodology/approachThe study employed a qualitative research design, and the research instrument was developed using per-defined measurement items adopted from prior studies; the items were slightly adjusted to fit the current context. The questionnaires were distributed to top and middle managers in selected banks in Tanzania using the snowball sampling technique. Out of 360 received responses, 302 were considered complete and valid for data analysis. The study employed partial least squares structural equation modeling (PLS-SEM) to examine the developed conceptual framework.FindingsTop management support and financial resources emerged as influential organizational factors, as did competition intensity for the environmental factors. Notably, bank size and perceived trends showed no significant impacts on BDA adoption. The study's novelty lies in revealing PR as a moderating factor, weakening the link between technological readiness, perceived usefulness and the intent to adopt BDA.Originality/valueThis study extends literature by extending the TOE model, through examining the moderating roles of PR on technological factors. Furthermore, the study provides useful managerial support for the adoption of BDA in banking in emerging economies.
Examining the drivers and barriers to adoption of e-government services in Saudi Arabia
Authors: Hasan Asif , Alenazy Amer Ali , Habib Sufyan , Husain Shahid 
Published: May 2024

PurposeThis study investigates the factors influencing citizen attitudes toward e-government services and their effects on the adoption of e-government services in Saudi Arabia. It sheds light on the moderating role of citizen motivation in the relationship between factors influencing citizen attitudes in favor of e-government services and their adoption and usage behavior in the Saudi Arabian context. The study analyzes both the drivers propelling the uptake and the barriers impeding it.Design/methodology/approachA descriptive research design was employed in this study, which surveyed 487 respondents from Jeddah and Madina cities and the surrounding region. The research identifies key drivers, including cultural factors, digital literacy, government policy and interventions, privacy and security, technical infrastructure, support services and citizen trust, alongside barriers such as concerns about data security and digital literacy.FindingsThe findings reveal the complex interplay of these factors in shaping citizen attitudes toward e-government services and their effects on adoption in Saudi Arabia. The study indicates that citizen motivation toward e-government services moderates the relationship between, adoption and usage behavior.Originality/valueThis study contributes valuable insights for policymakers and practitioners by offering a nuanced perspective on e-government service adoption in the Saudi Arabian context. It enhances our understanding of the factors influencing citizen attitudes and their impact on e-government adoption, highlighting the importance of citizen motivation as a moderating factor in this relationship.
Investigation of the speckle pattern effect for displacement assessments by DIC
Authors: Caliskan Salim , Akyuz Hakan 
Published: May 2024

PurposeThis study aims to investigate the effect of speckle pattern on displacement measurements using different speckle diameters and coverage ratios.Design/methodology/approachIn order to compare the coverage ratio and speckle diameter during the evaluation of the correlation of digital images (DIC) study, template speckle plates were produced on a computer numerical control (CNC) punch press with 600 punches per minute. After the speckle plates were manufactured, the speckled pattern was randomly painted on a plain white side through the manufactured template plates, and then tensile tests were performed under the same loading conditions for each sample to observe displacement variation via correlation parameters.FindingsDuring the manufacturing of templates with thin plates, a punch diameter of less than 1.7 mm will cause tool failure; therefore, uniform speckle size can be assessed before operation. A higher coverage ratio resulted in more accurate and reliable results in displacement data. With smaller coverage, the facet size should be increased to achieve favorable results.Research limitations/implicationsIf thick template plates are selected, speckle painting cannot be done properly; therefore, template thickness shall also be assessed before operation.Practical implicationsFor randomly distributed DIC templates, increasing coverage beyond 50% does not make sense due to difficulties in the production process in the punch press.Originality/valueEvaluating DIC results via templates manufactured in a punch press with different speckle diameters and coverage ratios is a new topic in literature.
Tides of change: employee training strategies for promoting risk-taking tourism in the North Sea
Authors: Bilderback Stephanie 
Published: May 2024

PurposeThis study critically examines the transformative impact of the “North Sea TikTok” phenomenon on the marine tourism sector, emphasizing the role of employee training in fostering resilience and adaptability within marine economics and integrated marine systems. It delves into how viral social media trends influence marine tourism destinations, particularly the North Sea, affecting local economies, marine resource management and tourism strategies. By analyzing this trend, the paper seeks to uncover how marine tourism destinations can effectively respond to the challenges and opportunities presented by digital media-driven tourism.Design/methodology/approachEmploying a multidisciplinary framework that merges insights from digital marketing, risk perception in tourism and human resource management, this paper provides a comprehensive qualitative analysis of the “North Sea TikTok” trend. Through a meticulous content analysis of viral videos and an examination of user engagement metrics, alongside a thorough review of contemporary literature in marine tourism and sustainability, the study unpacks the far-reaching implications of social media on marine tourism ecosystems.FindingsThe analysis reveals that the “North Sea TikTok” trend has markedly altered public perceptions of the North Sea, catalyzing a shift toward adventure and risk-taking tourism. This pivot promises economic rejuvenation for local tourism sectors and necessitates agile marine management strategies to accommodate the evolving demands. Implementing innovative employee training programs focusing on safety protocols, environmental conservation and digital engagement is central to managing these dynamics. The paper emphasizes integrating sustainable practices to ensure the equitable growth of marine tourism economies and environmental preservation.Originality/valueThis paper pioneers exploring the nexus between social media trends and their operational and strategic impacts on marine tourism management and economics. Synthesizing social media's viral dynamics with marine tourism development introduces groundbreaking insights into adapting marine tourism strategies in the digital age. It emphasizes the critical need for a skilled workforce capable of navigating the complexities of digital trend-driven tourism markets, proposing a novel model for employee training that aligns with the shifting paradigms of marine tourism engagement. This unique contribution advances academic discourse in marine economics and provides practical frameworks for stakeholders aiming to harness social media trends for sustainable tourism development.
‘You get sick when you go to the hospital!’ Sickening landscapes, digital exclusiveness, and iatrogenesis in rural North China
Authors: Qu Ray 
Published: May 2024

AbstractA local narrative current in North China's Shandong Province paints the hospital as a place where people become ill. This article foregrounds older rural people's embodied experience of navigating the medical system. This involves humiliation and feelings of incompetence in their interactions not only with other people whom they see as more sophisticated than them but also with unfamiliar things such as elevators and digital payment platforms. ‘Sickening landscapes’, a concept built upon this narrative, expands the notion of therapeutic landscapes to bring into sharp relief the negative effects of places and things and the embedded health inequities. It offers a native account of iatrogenesis, as something arising from mundane interactions with physical spaces, technologies, and people, which expands the current focus of clinical iatrogenesis on medical error, malpractices, and nosocomial infections. Incorporating the notion of ‘sickening landscapes’ into the theory of care helps us better attend to the trivial, easily neglected things and places that directly bear on the health and well‐being of marginalized social groups.
Examining teachers' perceived competence in implementing inclusive education practices in the United Arab Emirates
Authors: Loyd Daisy , Opoku Maxwell Peprah , Walker Zachary , Alhosani Najwa Mohamed , Elhoweris Hala , Almuhairy Osha , Mohamed Ahmed , Takriti Rachel Alison , Al Maktoum Sana Butti , Mohamed Amani , Jibar Hamdah , Baja Emmanuel , Garces‐Bacsal Rhoda Myra 
Published: May 2024

AbstractInclusive education in the United Arab Emirates (UAE) is evolving with ambitious policies and strategic plans. The extent to which these policies and plans are being embedded into practice in mainstream schools across the country has not been fully captured. This research used an online survey to investigate teachers' perceived competence in implementing inclusive education practices with students with disabilities in mainstream schools and explore its relationship with demographic variables. Participants included 999 teachers from public and private schools across the seven Emirates of the UAE. Greater competence was reported in implementing practices that create an environment conducive to effective learning and less competence in implementing practices that use knowledge of the student. Differences were found between demographic variables and teachers' perceived competence in implementing inclusive education practices with recent professional development in inclusive and/or special education emerging as the most significant predictor. Implications for practice and further research are considered.