bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective Analysis of Neonatal Hyperbilirubinemia at Hiwot Fana Specialized Hospital, Ethiopia: Prevalence, Associated Factors, and Treatment Outcomes
Authors: Abdirahman¹ Mohamed , Libe² Temesgen Teferi , Gebru³ Feven Mekonnen 
Published: May 2024

Abstract

Background
Neonatal hyperbilirubinemia, also known as neonatal jaundice, is a condition characterized by yellowish discoloration of the skin and eyes caused by bilirubin buildup in the body. Understanding its prevalence, associated factors, and outcomes is crucial for effective management.
Objectives
This study aimed to assess the prevalence, associated factors, and treatment outcomes of neonatal hyperbilirubinemia at Hiwot Fana Specialized Hospital, Eastern Ethiopia.
Methodology:
A hospital-based cross-sectional study was conducted from December 1, 2020, to December 30, 2020, involving 328 neonates admitted to the Neonatal Intensive Care Unit. Data were collected using a checklist and analyzed using SPSS version 22.
Result
Neonatal hyperbilirubinemia prevalence was 44.2%, with 1.4% progressing to bilirubin encephalopathy. Sepsis (44.8%) and prematurity (22%) were major contributing factors. Most neonates were treated with phototherapy alone (82.3%), and 93.8% showed improvement.
Conclusion
The study underscores the importance of early detection and management of neonatal hyperbilirubinemia to prevent adverse outcomes. Recommendations include integrating jaundice prevention into antenatal care and ensuring timely bilirubin level checks in neonates.
A first characterization of kinetochore proteins in the holocentric insect Spodoptera frugiperda
Authors: Gimenez  , Eychenne  , Legeai  , Gamble  , d'Alençon  
Published: May 2024

Abstract

Insects with holocentric chromosomes have a centromere spread all over their length and are devoid of the proteins CENP-A and CENP-C, suggesting a different kinetochore assembly process compared to that in monocentrics. Very recently, the homolog of CENP-T was shown to play a key role in kinetochore assembly in Bombyx mori and to bind to silent chromatin regions. However, nothing is known in other holocentric insects. In this paper, we set up a protocol to silence the kinetochore genes cenp-L, cenp-S, cenp-X and ndc80 and searched for chromosome segregation defects in Spodoptera frugiperda cells. We also analyzed their expression pattern in the insect. As shown by immunofluorescence microscopy and RT-QPCR, we succeeded to silence target genes efficiently by transfection with dsRNA. In Sf9 cells depleted for CENP-L and NDC80, by immunofluorescence microscopy, we observed an increase of mitotic indices linked to metaphase arrest and, respectively unaligned chromosomes and multipolar spindles. In cells depleted for CENP-S and CENP-X, the mitotic indices were unchanged and no division defects were observed. Except cenp-S and X, kinetochore genes were overexpressed in gonadal versus somatic tissues. We conclude that CENP-L and NDC80 play a major role in chromosome segregation, while the function of CENP-S and -X are still unknown. We started to characterize the kinetochore proteins (CENP-L, CENP-S, CENP-X, NDC80), a prerequisite for holocentromere identification in S. frugiperda. We provide the first clues on CENP-L in Lepidoptera, a protein playing a central role in the structure of the Constitutive Centromere Associated Network in monocentrics
Implementation of Inpatient Electronic Consultations During the COVID-19 Crisis and Its Sustainability Beyond the Pandemic: Quality Improvement Study
Authors: Aledia Anna S , Dangodara Amish A , Amin Aanya A , Amin Alpesh N 
Published: May 2024

Background
Limiting in-person contact was a key strategy for controlling the spread of the highly infectious novel coronavirus (COVID-19). To protect patients and staff from the risk of infection while providing continued access to necessary health care services, we implemented a new electronic consultation (e-consult) service that allowed referring providers to receive subspecialty consultations for patients who are hospitalized and do not require in-person evaluation by the specialist.

Objective
We aimed to assess the impact of implementing e-consults in the inpatient setting to reduce avoidable face-to-face referrals during the COVID-19 pandemic.

Methods
This quality improvement study evaluated all inpatient e-consults ordered from July 2020 to December 2022 at the University of California Irvine Medical Center. The impact of e-consults was assessed by evaluating use (eg, number of e-consults ordered), e-consult response times, and outcome of the e-consult requests (eg, resolved electronically or converted to the in-person evaluation of patient).

Results
There were 1543 inpatient e-consults ordered across 11 participating specialties. A total of 53.5% (n=826) of requests were addressed electronically, without the need for a formal in-person evaluation of the patient. The median time between ordering an e-consult and a specialist documenting recommendations in an e-consult note was 3.7 (IQR 1.3-8.2) hours across all specialties, contrasted with 7.3 (IQR 3.6-22.0) hours when converted to an in-person consult (P<.001). The monthly volume of e-consult requests increased, coinciding with surges of COVID-19 cases in California. After the peaks of the COVID-19 crisis subsided, the use of inpatient e-consults persisted at a rate well above the precrisis levels.

Conclusions
An inpatient e-consult service was successfully implemented, resulting in fewer unnecessary face-to-face consultations and significant reductions in the response times for consults requested on patients who are hospitalized and do not require an in-person evaluation. Thus, e-consults provided timely, efficient delivery of inpatient consultation services for appropriate problems while minimizing the risk of direct transmission of the COVID-19 virus between health care providers and patients. The service also demonstrated its value as a tool for effective inpatient care coordination beyond the peaks of the pandemic leading to the sustainability of service and value.
Surgical methods of treatment for tibial diaphyseal fractures
Authors: Stroiev M.Yu. , Karpinska O.D. 
Published: May 2024

Background. Bone fractures are a public health concern. In recent years, there has been an upward trend in body weight of people of all age groups. Obesity has long been thought to help protect against fractures, but recent studies have shown that for every 5 cm increase in waist circumference, the risk of any fracture is 3 % higher. The purpose: according to the meta-analysis of modern medical literature, to determine the main directions of surgical treatment for long bone fractures, their advantages, and disadvantages, including in overweight patients, the features of diaphyseal fracture fixation in overweight patients. Materials and methods. A meta-analysis of special literature from scientific databases was conducted: Cochrane Library, Scopus, National Library of Medicine — National Institutes of Health, ReLAB-HS Rehabilitation Resources Repository. One hundred and thirty articles were analyzed, from them 31 were selected, which, in our opinion, reflect the purpose of the study. Results. All methods of surgical fixation of fractures have their advantages and disadvantages. The frequency of nonunions caused by intramedullary fixation of the femoral shaft can reach 10 %, and varus/valgus and rotational deformities and shortening can also be observed. But the use of locking screws prevents the occurrence of most complications. When fixing the fractures with plates, the main complications are related to superficial and deep infections, which were more often observed in overweight patients. The analysis demonstrated that in overweight and obese patients, the main complicating factor is not the method for fixing the fracture zone, but factors related to the health of the patient himself. So, despite the fact that the results of treatment of fractures in patients with normal weight and obesity did not have a statistically significant difference, an increase in cardiovascular complications, exacerbation of chronic respiratory diseases was observed. Moreover, it is the presence of concomitant diseases that often makes surgical intervention impossible. Conclusions. There is a large amount of research on surgical methods of fixing tibial diaphyseal fractures, but data on the choice of fixation method in overweight and obese patients as a separate approach were not found. There are data on complicating factors of excess weight in the treatment of fractures and surgical interventions. Systematic studies related specifically to the algorithm for choosing the method of fracture fixation and complications have also not been found.
Analisis Tingkat Pendapatan Pengrajin Kendang Jimbe di Kota Blitar
Authors: Cahyani Adinia Dewi 
Published: May 2024

Abstract
Penelitian ini bertujuan Untuk mengetahui tingkat pendapatan terhadap pengrajin kendang jimbe di Kota Blitar. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan linier berganda. Data yang digunakan dalam penelitian ini diperoleh dari berbagai sumber, termasuk observasi dan kuesioner. Variabel-variabel yang digunakan dalam analisis adalah modal, jumlah tenaga kerja, serta biaya produksi. Perangkat lunak yang digunakan untuk melakukan analisis adalah E-views 9. Hasil dari penelitian menunjukkan bahwa variabel modal(X1) berpengaruh positif dan signifikan terhadap pendapatan pengrajin, variabel jumlah tenaga kerja (X2) berpengaruh negatif dan signifikan terhadap pendapatan pengrajin. variabel biaya produksi (X3) berpengaruh positif dan signifikan terhadap pendapatan pengrajin. Kemudian Variabel modal, jumlah tenaga kerja dan biaya produksi berpengaruh secara simultan terhadap tingkat pendapatan pengrajin berpengaruh signifikan. Variabel modal, jumlah tenaga kerja dan biaya produksi berpengaruh secara simultan terhadap tingkat pendapatan pengrajin. Hal ini di buktikan bahwa nilai signifikan sebesar 0,000 < 0.05.
Additional Comments of the American Accounting Association Auditing Section Auditing Standards Committee on the PCAOB’s Amendments to PCAOB Auditing Standards Related to a Company’s Noncompliance with Laws and Regulations and Other Related Amendments
Authors: Boland Colleen M. , Hermanson Dana R. , Higgs Julia L. , Prewett Kyleen W. , Pyzoha Jonathan S. , Tegeler Amy C. 
Published: May 2024

SUMMARY
In June 2023, the Public Company Accounting Oversight Board (the Board or PCAOB) issued a request for comment on its Amendments to PCAOB Auditing Standards Related to a Company’s Noncompliance with Laws and Regulations and Other Related Amendments (“NOCLAR”; PCAOB 2023a). On February 26, 2024, the PCAOB (2024) reopened the comment period for additional feedback, in conjunction with a March 2024 public roundtable about the proposal. This commentary summarizes the participating committee members’ views on the proposal that are incremental to our original comments provided previously (Boland et al. 2024). Due to ongoing fundamental concerns, as well as new evidence of extraordinarily different interpretations of the proposed standard, our lack of support for the proposal remains unchanged. We strongly encourage the PCAOB to issue a revised proposal for public comment before any final standard is issued or to consider other alternatives.
MOTIVASI BELAJAR PESERTA DIDIK KELAS 5 PASCA PEMBELAJARAN DARING DI SDN 1 MENAWAN
Authors: Mahatama Dikla Vindi 
Published: May 2024

Pembelajaran daring adalah pembelajaran jarak jauh melalui jaringan dengan memanfaatkan gadget dengan banyak cara. Pembelajaran harus beradaptasi dengan membutuhkan perencanaan yang matang. Untuk mengetahui bagaimana motivasi belajar peserta didik di kelas 5 pasca pembelajaran daring. Pada dunia pendidikan pentingnya motivasi diperlukan agar peserta didik semangat dalam mengikuti proses pembelajaran di SDN 1 Menawan yang berada di Desa Menawan, kecamatan Gebog, kabupaten Kudus.Mengubah pembelajaran tatap muka ke pembelajaran berbasis online melalui jaringan dengan memanfaatkan gadget membuat kondisi motivasi belajar peserta didik yang harus diperhatikan. Peserta didik yang bermotivasi tinggi dalam belajar akan memperoleh hasil belajar yang lebih tinggi, maka hasil yang didapat juga akan lebih tinggi dan sesuai dengan yang diharapkan. Pembelajaran akan berlangsung efektif apabila peserta didik memiliki motivasi dalam belajar. Oleh karena itu motivasi belajar menjadi salah satu kunci keberhasilan untuk mencapai tujuan pembelajaran.Penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Dilaksanakan pada kelas 5 di SDN 1 Menawan dengan subjek 27 peserta didik yang diseleksi menjadi menjadi 4 peserta didik dengan kriteria. Peserta didik yang paling pintar dan paling kurang, peserta didik dari latar belakang keluarga ekonomi mampu dan kurang mampu. Instrumen penelitian menggunakan teknik observasi dan wawancara.
Letters To The Editors
Authors: Refuge Editor  
Published: May 2024

With reference to the interesting article "Kosovar Refugee Assessments in Montenegro and Albania" by Brown and colleagues1 , we like to report on a similar survey conducted among Kosovar refugees in two Macedonian refugee camps on 1-3 May 1999. We are grateful to Vincent Brown who helped us designing our study and our questionnaire. We could fortunately draw upon his experience in the Montenegro survey.
Modified upwind and hybrid schemes on special grids for solving layered problems
Authors: Паасонен В.И. , Лисейкин В.Д. 
Published: May 2024

При решении на адаптивных сетках задач с пограничными и внутренними слоями весьма желательно пользоваться разностными схемами, сходящимися равномерно относительно малого параметра при стремлении шагов сетки к нулю. Однако равномерно сходящиеся схемы обычно имеют лишь первый порядок точности, а схемы высокой точности не сходятся равномерно. В работе исследуются свойства оригинальной модификации противопоточной схемы и построенных на ее основе двух гибридных схем, имеющих второй порядок точности и сходящихся равномерно по малому параметру. На модельной задаче с пограничным слоем экспоненциального типа на специальных адаптивных сетках проведены сравнения численных результатов, подтвердивших эффективность построенных гибридных схем в сравнении с известными однородными схемами.
Boundary and interior layers present serious difficulties for the efficient calculation of equations modelling many technical applications, in particular, those having a small parameter before the higher derivatives. Due to this phenomenon, developing uniformly convergent algorithms for solving such problems are difficult. Resources provided by numerical schemes and adaptive grids can significantly reduce the adverse effects on the accuracy of numerical experiments due to the layers. An efficient and popular scheme for solving two-point singularly-perturbed problems with layers is the upwind difference scheme. However, this scheme provides convergence of the first order only. In this paper, we are focused on two second-order uniformly convergent finite difference algorithms for solving two-point singularly-perturbed problems. The proposed algorithms apply a hybrid scheme based on the midpoint upwind approximation, Buleev’s scheme and special layer-resolving grids designed for solving problems with exponential and power layers of the first type. Numerical experiments conducted out for singularly perturbed problems confirm the efficiency of the algorithms for various values of the small parameter and show that the proposed method provides competitive results compared to other methods available in the literature.
EDUCATIONAL SUPPORT EFFECTS ON ENTREPRENEURSHIP BEHAVIOR: A STUDY OF ENTREPRENEURSHIP TRAINING PROGRAM
Authors: Dewantara Norman , Rai Ni Gusti Made , Noer Lissa Rosdiana 
Published: May 2024

Objective: This study investigates the impact of educational support on entrepreneurship behavior using the study of entrepreneurship training program.

Theoretical Framework: This study uses TPB (Theory of Planned Behavior) as a grand theory for understanding entrepreneurship behavior that will be combining with educational support as antecedent variable. TPB argued that individual’s behavior will be determined by attitude, subjective norms, perceived behavioral control, and intention.

Method: This study has 200 students selected with random-sampling method. Online survey with a self-administered is used to collect data. The stage of data analysis consists of demographic distribution analysis, research construct test, model fit test, and hypothesis test.

Findings: This study shows that educational support has a positive effect on entrepreneurship intention that is mediated by attitude towards entrepreneurship, perceived behavioral control, and subjective norms. This study also found a relationship between entrepreneurship intention and entrepreneurship behavior.

Implications: The universities must evaluate the actions that students have taken as long as training program. Universities are needed to make sure that students have developed a real business plan. The Government of Indonesia also need to build partnerships with business network, such as investors to help fund the business. Thus, educational support will be affected to improve the number of entrepreneurs in Indonesia.

Originality/Value: This study confirms the concept of entrepreneurship intention which is an important step in improving student entrepreneurship behavior.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN STUNTING PADA ANAK BALITA
Authors: Dewi Adinda Putri Sari , Kusumastuti Kusumastuti , Astuti Dyah Puji 
Published: May 2024

AbstrakStunting adalah salah satu keadaan malnutrisi yang bersifat kronik yang dapat menimbulkan gangguan perkembangan fisik, penurunan kognitif serta penurunan motorik. Stunting pada anak balita merupakan konsekuensi dari beberapa faktor yang sering dikaitkan dengan kemiskinan termasuk gizi, kesehatan, sanitasi dan lingkungan. Tujuan penelitian ini untuk mengetahui faktor-faktor yang mempengaruhi kejadian stunting pada anak balita.Penelitian ini merupakan jenis penelitian observasional analitik dengan desain kasus kontrol. Sampel yang diambil sebanyak 24 balita untuk masing-masing kelompok kasus maupun kontrol dengan teknik simple random sampling. Analisis data menggunakan chi square dengan α=0,05 pada interval kepercayaan 95% dan regresi logistik pada interval kepercayaan 95%.Hasil analisis menunjukan bahwa faktor yang mempengaruhi terjadinya stunting di desa Semali Kecamatan Sempor Kabupaten Kebumen adalah riwayat pemberian ASI Eksklusif (OR=3,40; CI=1,03-11,07), Riwayat Penyakit Infeksi (OR=3,54; CI=1,05-11,92), dan Keteraturan Menimbang di posyandu (OR=0,020; CI=1,04-16,19). Namun untuk faktor riwayat BBLR, pola asuh makan, dan pendapatan keluarga tidak mempengaruhi terjadinya stunting.Terdapat hubungan antara riwayat pemberian ASI Eksklusif, Riwayat Penyakit Infeksi, dan Keteraturan Menimbang di posyandu terhadap kejadian stunting pada balita.Keywords: Stunting, Anak Balita, ASI Eksklusif AbstractStunting is chronic malnutrition that can cause physical Developmental Problems, reduced cognitive and motor function. Stunting among children under 5 years of age is the consequence of several factors that are often associated with poverty, including nutrition, health, sanitation and environment. The aim of this research is to determine the factors affecting the prevalence of stunting in children under five years of age.This research is analytical observational study with A case-control design. Samples were 24 toddlers for each of case and control group using Simple random sampling. Data analysis was conducted by chi-square test with α = 0.05 at the 95% confidence interval and the logistic regression at the 95% confidence interval.The result of the analysis shows that the factors influencing the occurrence of stunting in Semali Village, Sempor District, Kebumen Regency is the record of exclusive breastfeeding. (OR = 3.40; CI = 1.03-11.07), the record of infectious diseases (OR = 3.54; CI = 1.05-11.92), and the regularity measuring weight of children at Posyandu (OR = 0.020; CI = 1.04-16.19). However, the factors of low birth weight history, dietary care, and family income do not influence the occurrence of stunting.There is a relationship among history of exclusive breastfeeding, history of infectious diseases, and regularity measuring weight of children at Posyandu to the incidence of stunting in children under five years of age.Keywords: stunting, toddler, exclusive breastfeeding
PELATIHAN KADER POSYANDU MENINGKATKAN PENGETAHUAN SKRINING PERTUMBUHAN DAN PERKEMBANGAN BALITA
Authors: Noprida Dayana , Palopa Damayanti , Sarini Sarini , Imroatun Tri , Agustina Wahyuni , Sahariah Sahariah , Sutini Titin , Apriliawati Anita , Purwati Nyimas Heny 
Published: May 2024

Pada masa periode emas, balita akan mengalami pertumbuhan dan perkembangan dengan cepat serta tidak dapat terulang kembali. Adanya penyimpangan pada tahap ini akan sulit diatasi bila sudah terlambat terjadi. Adanya skrining perkembangan pada balita menggunakan Kuesioner Pra Skrining Prekembangan (KPSP) menjadi fasilitasi untuk melakukan deteksi secara dini. Skrining KPSP dapat dilakukan oleh tenaga non kesehatan termasuk Kader. Kecamatan Pasar Rebo Jakarta Timur memiliki jumlah kader yang banyak namun masih sedikit yang memiliki pengetahuan tentang skrining KPSP. Adanya pandemic Covid membuat pertemuan secara langsung tidak dapat dilakukan. Pelatihan off the job training dapat menjadi alternatif bagi kader Posyandu Balita. Tujuan penelitian ini adalah untuk mengetahui pengaruh pelatihan kader terhadap peningkatan pengetahuan skrining dengan instrumen KPSP pada kader Posyandu wilayah Pasar ReboDesain penelitian menggunakan Pre experiment one group pre-test-posttest without control. Subjek penelitian ini adalah kader Posyandtu Wilayah Pasar Rebo Jakarta Timur yang memenuhi kriteria inklusi dan eksklusi. Jumlah sampel pada penelitian sebanyak 70 kader. Penelitian menggunakan metode off the job training via zoom meeting. Analsis data menggunakan uji T Paired. Hasil penelitian didapatkan peningkatan pengetahuan rata-rata kader adalah 29,64±13,08. Uji statistic didapatkan p value=0,000 yang berarti bahwa ada pengaruh pelatihan kader posyandu terhadap peningkatan pengetahuan tentang skrining pertumbuhan dan perkembangan balita dengan KPSP di Wilayah Pasar Rebo Jakarta. Pelatihan kader dengan metode off the job training dinilai efektif pada masa pandemic Covid 19 untuk meningkatkan pengetahuan kader dalam deteksi perkembangan bayi menggunakan KPSP.