bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: TiCl4—Et2AlCl‐Catalyzed Cycloaddition of 1,2‐Dienes to 1,3,5‐Cycloheptatriene.
Authors: D'yakonov V. A. , Nadikova G. N. , Khalilov L. M. , Dzhemilev U. M. 
Published: January 2012

AbstractSubstituted endo‐bicyclo[4.2.1]nona‐2,4‐dienes are obtained by catalytic codimerization of 1,3,5‐cycloheptatriene (I) with 1,2‐dienes (II) in the presence of the title two‐component catalytic system.
ChemInform Abstract: Nano TiO2 as a Heterogeneous Catalyst in an Efficient One‐Pot Three‐Component Mannich Synthesis of β‐Aminocarbonyls.
Authors: Kassaee M. Z. , Mohammadi Reza , Masrouri Hassan , Movahedi Farnaz 
Published: January 2012

AbstractModerate to good anti‐selectivity is observed for cyclic ketones with the exception of (IVa/Va).
ChemInform Abstract: Efficient Indoles and Anilines Synthesis Employing tert‐Butyl Sulfinamide as Ammonia Surrogate.
Authors: Prakash Anjanappa , Dibakar Mullick , Selvakumar Kumaravel , Ruckmani Kandasamy , Sivakumar Manickam 
Published: January 2012

AbstractPalladium catalyzed coupling of sulfinamide (II) with aryl halides gives sulfinated anilines which can be deprotected with HCl.
ChemInform Abstract: A Highly Active Nano‐Palladium Catalyst for the Preparation of Aromatic Azos under Mild Conditions.
Authors: Hu Lei , Cao Xueqing , Shi Linyan , Qi Fenqiang , Guo Zhiqiang , Lu Jianmei , Gu Hongwei 
Published: January 2012

AbstractThe worm‐like Pd nanomaterial allows the preparation of various symmetrical and unsymmetrical azo compounds.
ChemInform Abstract: Direct and Mild Palladium‐Catalyzed Aerobic Oxidative Synthesis of Imines from Alcohols and Amines under Ambient Conditions.
Authors: Jiang Lan , Jin Luolu , Tian Haiwen , Yuan Xueqin , Yu Xiaochun , Xu Qing 
Published: January 2012

AbstractBy ligand, (TEMPO) and base screening a mild one pot imine synthesis from benzylic alcohols (I) and amines (II) via a Pd‐catalyzed tandem aerobic alcohol oxidation/dehydrative condensation sequence is developed.
ChemInform Abstract: Organocatalytic Asymmetric Aldol Reaction of Hydroxyacetone with β,γ‐Unsaturated α‐Keto Esters: Facile Access to Chiral Tertiary Alcohols.
Authors: Liu Chen , Dou Xiaowei , Lu Yixin 
Published: January 2012

AbstractThe reaction is effective only for aromatic ketoesters.
ChemInform Abstract: Microwave Promoted Rapid Dehydration of Aldoximes to Nitriles Using Melamine‐Formaldehyde Resin Supported Sulfuric Acid in Dry Media.
Authors: Rezaei Ramin , Karami Marzeih 
Published: January 2012

AbstractThe process allows the conversion of aromatic and aliphatic aldoximes in short reaction times.
ChemInform Abstract: Synthesis of tert‐Butyl Peresters from Aldehydes by Bu4NI‐Catalyzed Metal‐Free Oxidation and Its Combination with the Kharasch—Sosnovsky Reaction.
Authors: Wei Wei , Zhang Chao , Xu Yuan , Wan Xiaobing 
Published: January 2012

AbstractA new tert‐butyl perester synthesis directly from aldehydes (I) and tert‐butyl hydroperoxide (II) is developed via Bu4NI‐catalyzed aldehyde C—H oxidation.
ChemInform Abstract: Convenient One‐Pot Synthesis of Sulfonamides and Sulfonyl Azides from Thiols Using N‐Chlorosuccinimide.
Authors: Veisi Hojat , Ghorbani‐Vaghei Ramin , Hemmati Saba , Mahmoodi Jafar 
Published: January 2012

AbstractA procedure is developed which produces alkyl and aryl sulfonyl chlorides from the corresponding thiols in the first step followed by direct one‐pot conversion to the title compounds.
ChemInform Abstract: Silicon‐Mediated Synthesis and Selected Transformations of β‐Chloroketones.
Authors: Salama Tarek A. , Elmorsy Saad S. 
Published: January 2012

AbstractThe attempt to use aliphatic unsaturated ketones or arylidenes of alicyclic ketones fails.The β‐chloroketones are converted into tetrazoles and β‐amidoketones and SiCl4 can be applied in all transformation as an efficient reagent.
ChemInform Abstract: Suzuki—Miyaura Cross‐Coupling of Benzylic Bromides under Microwave Conditions.
Authors: McDaniel Steven W. , Keyari Charles M. , Rider Kevin C. , Natale Nicholas R. , Diaz Philippe 
Published: January 2012

AbstractThe optimized conditions allow the preparation of a library of structurally diverse products what is of interest for SAR studies in the field of isoxazole drugs.
ChemInform Abstract: Hexatriene Formation from the Regiospecific Alkene Cross‐Metathesis of trans‐1‐(Buta‐1,3‐dien‐1‐yl)‐2‐acryloyloxynaphthalene.
Authors: Gabbutt Christopher D. , Heron B. Mark , Kilner Colin , Kolla Suresh B. 
Published: January 2012

AbstractAttempted synthesis of the medium‐ring size lactone naphthoxocinone via ring‐closing metathesis of readily available acrylate ester (V) fails but yields the hexatriene (VI).
ChemInform Abstract: Expeditious Synthesis of Phenanthrenes via CuBr2‐Catalyzed Coupling of Terminal Alkynes and N‐Tosylhydrazones Derived from O‐Formyl Biphenyls.
Authors: Ye Fei , Shi Yi , Zhou Lei , Xiao Qing , Zhang Yan , Wang Jianbo 
Published: January 2012

AbstractThe reaction does not require any ligands and proceeds via coupling/cyclization of terminal alkynes and N‐tosylhydrazones.
ChemInform Abstract: A Powerful Cascade Approach for Expeditious Synthesis of Trifluoromethylated Furans.
Authors: Wang Yao , Luo Yong‐Chun , Hu Xiu‐Qin , Xu Peng‐Fei 
Published: January 2012

AbstractTetra‐substituted furan derivatives are prepared with excellent yields from α,β‐unsaturated ketoesters and TFAA.
ChemInform Abstract: Organocatalytic Asymmetric Henry Reaction of Isatins: Highly Enantioselective Synthesis of 3‐Hydroxy‐2‐oxindoles.
Authors: Zhang Yong , Li Zhi Jun , Xu Hai Sen , Zhang Yuan , Wang Wei 
Published: January 2012

AbstractThe methodology is also applied as the key step for the total synthesis of (R)‐dioxibrassinin (IV) and the formal synthesis of (S)‐spirobrassinin (V).
ChemInform Abstract: Novel Indole and Azaindole (Pyrrolopyridine) Cannabinoid (CB) Receptor Agonists: Design, Synthesis, Structure—Activity Relationships, Physicochemical Properties and Biological Activity.
Authors: Blaazer Antoni R. , Lange Jos H. M. , van der Neut Martina A. W. , Mulder Arie , den Boon Femke S. , Werkman Taco R. , Kruse Chris G. , Wadman Wytse J. 
Published: January 2012

AbstractThe discovery, synthesis, and SAR of a novel series of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands are reported.
ChemInform Abstract: Phosphine‐Initiated General Base Catalysis: Facile Access to Benzannulated 1,3‐Diheteroatom Five‐Membered Rings via Double‐Michael Reactions of Allenes.
Authors: Szeto Judy , Sriramurthy Vardhineedi , Kwon Ohyun 
Published: January 2012

AbstractThe reaction succeeds also with DMAP as basic catalyst, but mostly with lower yields.
ChemInform Abstract: Silica Chloride Catalyzed One‐Pot Synthesis of Fully Substituted Pyrazoles.
Authors: Jawale Dhanaji V. , Pratap Umesh R. , Mali Jyotirling R. , Mane Ramrao A. 
Published: January 2012

AbstractThe protocol avoids highly toxic reagents and is suitable for the synthesis of libraries.
ChemInform Abstract: Sulfuric Acid {[3‐(3‐Silicapropyl)sulfanyl]propyl}ester, a Recyclable Catalyst for the Synthesis of 2‐Aryl‐1‐arylmethyl‐1H‐1,3‐benzimidazole Derivatives.
Authors: Iravani Nasir , Mohammadzade Negar Safikhani , Niknam Khodabakhsh 
Published: January 2012

AbstractThe process works well with aromatic aldehydes, whereas alkyl aldehydes and cyclohexanone do not react.
ChemInform Abstract: One‐Pot Tandem Approach for the Synthesis of Benzimidazoles and Benzothiazoles from Alcohols.
Authors: Raghavendra Goravanahalli M. , Ramesha Ajjahalli B. , Revanna Cigalli N. , Nandeesh Kebbahalli N. , Mantelingu Kempegowda , Rangappa Kanchugarakoppal S. 
Published: January 2012

AbstractT3P is an efficient and mild reagent which allows the direct use of alcohols in the process without the need for an additional oxidant.
ChemInform Abstract: Catalytic Asymmetric Synthesis of Isoxazoline‐N‐oxides Through Conjugate Addition—Cyclization under Phase‐Transfer Conditions.
Authors: Kano Taichi , Yamamoto Akihiro , Song Sunhwa , Maruoka Keiji 
Published: January 2012

AbstractThe application of a chiral phase‐transfer catalyst gives the isoxazoline‐N‐oxide products (III)/(V) with moderate to good yields and enantioselectivity.
ChemInform Abstract: Synthesis of Novel Spiro(indolone‐3,2′‐[1,3,4]thiadiazol)‐2‐ones and Evaluation of Their Antidepressant and Anticonvulsant Activities.
Authors: Hassan Alaa A. , Abdel‐Latif Fathy F. , El‐Din Ahmed M. Nour , Abdel‐Aziz Mohamed , Mostafa Sara M. , Braese Stefan 
Published: January 2012

AbstractThe compounds (III) exhibit remarkable antidepressant activity compared with imipramine and compared with phenobarbital they show a good protection against clonic seizures induced by ip injection of pentylenetetrazol in mice (no yields given).
ChemInform Abstract: A Novel One Pot Route to Flavones under Dual Catalysis, an Organo‐ and a Lewis Acid Catalyst.
Authors: Maiti Gourhari , Karmakar Rajiv , Bhattacharya Rudraksha N. , Kayal Utpal 
Published: January 2012

AbstractAir can be used as the stoichiometric oxidant in the presence of ecofriendly FeCl3.The products, which represent structures of insecticidal agents, are easily isolated.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Some 1‐Substituted Amino‐4, 6‐Dimethyl‐2‐oxo‐pyridine‐3‐carbonitrile Derivatives.
Authors: Khidre Rizk E. , Abu‐Hashem Ameen A. , El‐Shazly Mohamed 
Published: January 2012

AbstractStarting from the known pyridone (II) as key precursor, a series of novel amine condensation products are prepared by classical methods.
ChemInform Abstract: Four‐Component Synthesis of Functionalized 2,2′‐Bipyridines Based on the Blaise Reaction
Authors: Hommes Paul , Jungk Phillip , Reissig Hans‐Ulrich 
Published: January 2012

AbstractE/Z‐Mixtures of N‐acylated‐β‐ketoamides are prepared from the corresponding nitriles and used as efficient precursors for the TmsOTf‐promoted cyclization to 4‐hydroxypyridine derivatives.
ChemInform Abstract: Copper‐Catalyzed Domino Oxidation—Acyloxylation Reaction of 2‐Arylpyridines with Aldehydes or Methylarenes.
Authors: Bian Yong‐Jun , Xiang Chang‐Bing , Chen Zhi‐Ming , Huang Zhi‐Zhen 
Published: January 2012

AbstractCarboxylic acids, generated in situ by oxidation of aldehydes or methyl arenes, react with substrates (I) and (IX) to afford the desired acyloxylated products with high ortho selectivity.
ChemInform Abstract: An Efficient One‐Step Synthesis of 2‐Arylquinolin‐4(1H)‐ones with the Aid of a Low‐Valent Titanium Reagent.
Authors: Sun Fang , Zhao Xuan , Shi Daqing 
Published: January 2012

AbstractThe optimized conditions allow the synthesis of title compounds (II)(10 examples) via cyclization of 2‐nitrochalcones bearing an aryl substituent at the double bond.
ChemInform Abstract: Synthesis of Aminoindolizine and Quinoline Derivatives via Fe(acac)3/TBAOH‐Catalyzed Sequential Cross‐Coupling—Cycloisomerization Reactions.
Authors: Patil Sachin S. , Patil Sachin V. , Bobade Vivek D. 
Published: January 2012

AbstractOptimized conditions allow the preparation of a broad spectrum of the target heterocycles.
ChemInform Abstract: Potassium Ferro Cyanide Trihydrate Complex Catalyzed One‐Pot Synthesis of 2‐Phenylimidazo[4,5‐f][1,10]phenanthroline.
Authors: Ali Syed Shahed 
Published: January 2012

AbstractSimple grinding of dione (I), aromatic aldehydes, and ammonium acetate in the presence of the catalyst produces products (III).
ChemInform Abstract: Multicomponent Synthesis of Pyridazine and Pyridazinoquinazoline Derivatives in the Presence of Catalysts such as Magnesium Oxide (MgO) and 12‐Tungstophosphoric Acid (PW).
Authors: Sheibani Hassan , Esfandiarpoor Zeinab 
Published: January 2012

AbstractA one‐pot three‐component procedure for the synthesis of the compounds (IV), (VI), and (VIII), which includes the use of an inexpensive and readily available catalyst, is presented.
ChemInform Abstract: Base‐Catalyzed Povarov Reaction: An Unusual [1,3] Sigmatropic Rearrangement to Dihydropyrimidobenzimidazoles.
Authors: Chen Chih‐Hau , Yellol Gorakh S. , Lin Po‐Tsung , Sun Chung‐Ming 
Published: January 2012

AbstractThe reaction of benzimidazoleamines with carbonyl compounds and dienophiles proceeds under microwave‐assisted conditions affording products of the type (IV), (VI) or (XI) depending on the nature of the carbonyl compound and dienophile.
ChemInform Abstract: CeCl3·7H2O‐Catalyzed Synthesis of Quinoxaline Derivatives in Liquid PEG‐400.
Authors: Wu Fang‐Wen , Hou Rei‐Sheu , Wang Huey‐Min , Kang Iou‐Jiun , Chen Ling‐Ching 
Published: January 2012

AbstractPhenacyl bromides (II) possessing electron‐donating and ‐withdrawing substituents on the aromatic ring react with o‐phenylenediamine (I) in an alternative reaction medium in the presence of cerium chloride heptahydrate as a novel catalyst to afford the 2‐aryl‐substituted quinoxalines (III) and (V) in very good yields.
ChemInform Abstract: Synthesis and Pharmacological Evaluations of Novel 2H‐Benzo[b][1,4]oxazin‐3(4H)‐one Derivatives as a New Class of Anticancer Agents.
Authors: Rajitha Chittipaka , Dubey P. K. , Sunku Venkataiah , Piedrafita F. Javier , Veeramaneni Venugopal Rao , Pal Manojit 
Published: January 2012

AbstractBased on key intermediate (III), novel 2H‐benzo[b][1,4]oxazin‐3(4H)‐one derivatives (VI), (VIII), and (XI) are synthesized and tested for their in vitro anti‐cancer properties against A549, DLD‐1, and MV4‐11 cell lines.
ChemInform Abstract: One‐Step Ring‐Closure Procedure for 4,5‐Dihydro‐1,3‐thiazino[5,4‐b]indole Derivatives with Lawesson′s Reagent. The Fifth Dihydro‐1,3‐thiazino[b]indole Isomer.
Authors: Csomos Peter , Fodor Lajos , Bernath Gabor , Csampai Antal , Sohar Pal 
Published: January 2012

AbstractA convenient approach for the synthesis of the title compounds (III) with a new ring system is presented.
ChemInform Abstract: Annulation of Furan‐Bridged 10‐Membered Rings on N‐Heterocycles Through [8 + 2] Cycloaddition of Dienylazaisobenzofurans and Dimethyl Acetylenedicarboxylate.
Authors: Roy Priyabrata , Ghorai Binay K. 
Published: January 2012

Abstracto‐Alkynyl substituted N‐heterocyclic ketones of type (I) and (V) react with the chromium carbene complex (II) to generate a dienylazaisobenzofuran intermediate which undergoes [8 + 2] cycloaddition with DMAD.
ChemInform Abstract: Copper‐Free Intramolecular Alkyne—Azide Cycloadditions Leading to Seven‐Membered Heterocycles.
Authors: Sau Miriam , Rodriguez‐Escrich Carles , Pericas Miquel A. 
Published: January 2012

AbstractThe reaction of the chiral oxirane substrates with sodium azide proceeds under microwave‐assisted conditions via ring opening and azide‐alkyne cycloaddition.
ChemInform Abstract: Catalytic Palladium Phosphination: Modular Synthesis of C1‐Symmetric Biaryl‐Based Diphosphines.
Authors: Bonnafoux Laurence , Gramage‐Doria Rafael , Colobert Francoise , Leroux Frederic R. 
Published: January 2012

AbstractA straightforward access to target compounds (III) without formation of the undesired phosphafluorene side‐product is presented.
ChemInform Abstract: Enantioselective Organocatalytic Phospha‐Michael Reaction of α,β‐Unsaturated Aldehydes.
Authors: Luo Xiaoyan , Zhou Zhiqiang , Li Xin , Liang Xinmiao , Ye Jinxing 
Published: January 2012

AbstractThe title reaction offers a new and easy method for the direct preparation of chiral phosphine oxide derivatives from pentavalent diaryl phosphine oxides and unsaturated aldehydes in the presence of a simple chiral pyrrolidine derivative as catalyst.
ChemInform Abstract: One‐Pot (1‐Ethoxycarbonylcyclopropyl)triphenylphosphonium Tetrafluoroborate Ring‐Opening and Wittig Reaction.
Authors: Chung Seung Won , et al. et al. 
Published: January 2012

AbstractVarious nucleophilic substrates are treated with NaH and converted to the ring‐opening addition product with the Wittig reagent (I).
ChemInform Abstract: Bioactive Cembranoids from the Dongsha Atoll Soft Coral Lobophytum crassum.
Authors: Tseng Yen‐Ju , Wen Zhi‐Hong , Hsu Chi‐Hsin , Dai Chang‐Feng , Sheu Jyh‐Horng 
Published: January 2012

AbstractTwo new metabolites, crassumolides H and I (Ib) and (II), and crassumolide G (Ia), which is discovered for the first time from natural sources, are isolated from the title coral.
ChemInform Abstract: Antitumor Activity of New Artemisinin—Chalcone Hybrids.
Authors: Xie Lijun , Zhai Xin , Liu Chun , Li Peng , Li Yangxiong , Guo Guoxian , Gong Ping 
Published: January 2012

AbstractA variety of new artemisinin‐chalcone hybrids are designed, synthesized and tested for their antitumor activity.
ChemInform Abstract: General and Scalable Amide Bond Formation with Epimerization‐Prone Substrates Using T3P and Pyridine.
Authors: Dunetz Joshua R. , Xiang Yanqiao , Baldwin Aaron , Ringling Justin 
Published: January 2012

AbstractThe general protocol allows the preparation of a variety of carboxylic amides from acids, including amino acids, on a gram to a kilogram scale without significant epimerization.
ChemInform Abstract: Synthesis of α‐C‐Glycosides by Samarium Diiodide Mediated Coupling of Glycosyl Pyridyl Sulfones with Alkenes.
Authors: Li Gen , Xiong De‐Cai , Ye Xin‐Shan 
Published: January 2012

AbstractOptimized conditions are elaborated for the diastereoselective preparation of the target compounds.
ChemInform Abstract: Synthesis and in vitro Activity of Novel N‐3 Acylated TSAO‐T Compounds Against HIV‐1 and HCV.
Authors: Postel Denis , et al. et al. 
Published: January 2012

AbstractAn efficient protocol for the regioselective acylation of TSAO‐T (I) at position N‐3 using acyl chlorides under phase‐transfer conditions is developed.
ChemInform Abstract: Synthesis and Biological Activity of Novel Tiliroside Derivants.
Authors: Qin Nan , Li Chun‐Bao , Jin Mei‐Na , Shi Li‐Huan , Duan Hong‐Quan , Niu Wen‐Yan 
Published: January 2012

AbstractNewly synthesized title compounds (III) are evaluated for antidiabetic properties in vitro.
Benefit‐Risk Assessment of Current Antiarrhythmic Drug Therapy of Atrial Fibrillation
Authors: Hohnloser Stefan H. 
Published: January 2012

AbstractOver the last decade, several rhythm‐versus rate‐control trails in patients with atrial fibrillation (AF) have failed to demonstrate benefit of the rhythm control strategy with respect to mortality and morbidity. This had let to the guideline recommendation that antiarrhythmic drug therapy should be considered predominantly for sympt0matic improvement of patients. Recent trails and meta‐analyses have demonstrated that amiodarone is the most antiarrhythmic drug currently available. However, its use has been associated with many adverse effects. Currently, dronedarone is the only available antiarrhythmic drug which has shown a reduction in cardiovascular hospitalizations in medium‐risk AF patients. However, the drug was associated with increased mortality in patients with recently decompensated heart failure. Hence, antiarrhythmic drug therapy has to be evaluated in patients with AF on an individual patients basis.Dr. Hohnloser received an honorarium through an educational grant from Sanofi Aventis for time and expertise spent writing this article. Dr. Hohnloser reports receiving consulting fees from Bayer, BMS; Cardiome, Pfizer, MSD, and Sanofi Aventis; research grants from Sanofi Aventis and St. Jude Medical, and lecture fees from BMS, Cardiome, Medtronic, Sanofi Aventis, and St. Jude Medical.
Carotid Artery Stenting in Clinical Practice: Does Sex Matter? Results From the Carotid Artery Stenting Registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)
Authors: Werner Nicolas , Zeymer Uwe , Mark Bernd , Hochadel Matthias , Hauptmann Karl Eugen , Jung Jens , Hoffmann Ellen , Elsässer Albrecht , Fürste Thomas , Leschke Matthias , Mudra Harald , Zahn Ralf ,   Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)
Published: January 2012

AbstractBackground:Carotid artery stenting (CAS) is increasingly used for treatment of severe carotid artery stenosis, but only few procedural risk factors for complications of CAS are clearly defined yet. A possible impact of the patient's gender on the outcome of patients undergoing CAS has not been investigated properly and only little information about this topic is available so far.Methods:We analysed data of the German prospective, multicenter CAS Registry of the Arbeitsgemeinschaft leitende kardiologische Krankenhausärzte.Results:From July 1996 to May 2009 5130 patients underwent CAS at 35 German hospitals and were enrolled into the prospective ALKK CAS Registry. Therefrom 1443 (28.1%) patients were female. There was no significant time‐related difference in the proportion of women undergoing CAS over the years. Women undergoing CAS were significantly older than men (73 years vs. 70 years, p < 0.01) and had a longer in hospital stay in comparison to men (p < 0.01). The majority of patients treated with CAS was between 60 and 80 years of age (∼73%). No significant differences between women and men could be found regarding in‐hospital events like death (0.5% vs. 0.5%, p = 0.99), major or minor stroke (1.7% vs. 1.6%, p = 0.97; 1.0% vs. 1.6%, p = 0.12), TIA (2.8% vs. 2.6%, p = 0.64), amaurosis fugax (0.3% vs. 0.5%, p = 0.25) , intracranial bleeding (0.5% vs. 0.3%, p = 0.43), myocardial infarction (0.1% vs. 0.0%, p = 0.48) or all non‐fatal strokes and all death (3.0% vs. 3.4%, p = 0.47). 30 day event rates did not show gender related differences in the combined endpoint of the outcome of patients undergoing CAS, as well (♀ n = 31/882 [3.5%] vs. ♂ n = 109/2273 [4.8%], p = 0.12).Conclusion:Our results do not suggest any gender‐related differences in success rates and complications in CAS. In clinical practice approximately 30% of patients treated with CAS are women.The institutions and people who participated in the ALKK CAS Registry are listed in Zahn et al.16 The authors have no funding, financial relationships, or conflicts of interest to disclose.
Atrial Fibrillation and Risk
Authors: John Camm A. 
Published: January 2012

AbstractDr. Camm received an honorarium through an educational grant from Sanofi Aventis to serve as Guest Editor of this supplement. He discloses no other direct conflicts of interest to the submitted work. Dr. Camm has served as a consultant, received grant funding, and has been a member of the speakers bureau for Sanofi Aventis.
Assessment of Water Quality in the Elbe River at Flood Water Conditions Based on Cluster Analysis, Principle Components Analysis, and Source Apportionment
Authors: Baborowski Martina , Simeonov Vasil , Einax Jürgen W. 
Published: January 2012

AbstractAn assessment of water quality measurements during a spring flood in the Elbe River is presented. Daily samples were taken at a site in the middle Elbe, which is part of the network of the International Commission for the Protection of the Elbe River (IKSE/MKOL). Cluster analysis (CA), principal components analysis (PCA), and source apportionment (APCS apportioning) were used to assess the flood‐dependent matter transport. As a result, three main components could be extracted as important to the matter transport in the Elbe River basin during flood events: (i) re‐suspended contaminated sediments, which led to temporarily increased concentrations of suspended matter and of most of the investigated heavy metals; (ii) water discharge related concentrations of pedogenic dissolved organic matter (DOM) as well as preliminary diluted concentrations of uranium and chloride, parameters with stable pollution background in the river basin; and (iii) abandoned mines, i.e., their dewatering systems, with particular influence on nickel, manganese, and zinc concentrations.