bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost and Damage Comparison of RC Frame Buildings Designed by IS Code and Unified Performance-Based Design Method
Authors: Das Tushar Kanti , Choudhury Satyabrata , Das Pallab 
Published: April 2024

Abstract

Seismic design code of India follows the traditional forced-based approach for designing buildings to resist a lateral force representing the earthquake excitations. Owing to various limitations of this approach, there is a growing interest towards Performance-Based Design (PBD) when designing buildings for seismic events. The Unified Performance-Based Design (UPBD) is a new and advanced PBD approach capable of effectively designing buildings for specific performance levels and drift. Despite its potential benefits, the widespread adoption of PBD remains limited especially, in India. To address this gap, a comprehensive study was conducted to evaluate the effectiveness of two distinct design methodologies: the conventional force-based Indian Standard (IS) code method and the innovative UPBD approach. The study focused on analysing the cost implications and seismic damage outcomes of each method. Nine reinforced concrete frame buildings were initially designed using the IS code method, followed by detailed nonlinear analyses to assess their performance. Subsequently, the buildings are redesigned using UPBD to achieve equivalent performance levels and drift, setting a standardized benchmark for comparison. Cost is assessed based on the weight of concrete and steel, while a modified Park and Ang Damage Index is used to quantify damage. The research findings unveiled that buildings designed using the UPBD method exhibited lower overall costs and showcased reduced vulnerability to structural damage compared to those designed using the traditional IS code approach. The UPBD-designed buildings demonstrate superior performance metrics and potential cost savings, emphasizing the economic and structural benefits of adopting the UPBD method for seismic design.
Awareness of medical students about septic shock at the Syrian Private University
Authors: Mohammed Ali , Yassin Talat , Ali Diaa Haj , Rakmani Najwa 
Published: April 2024

Abstract
Background
Shock is a condition of inadequate tissue perfusion resulting in decreased oxygen and metabolic requirements. It can lead to disturbance in energy production changes in cellular metabolism and significant acidosis. Various body systems are exposed to dysfunction and sometimes death if appropriate and intensive therapeutic measures are not taken early. Septic shock is the common final pathway by which many diseases and deaths occur.
Research Materials and Methods
A retrospective cohort study (COHORT) was conducted On a random group of elderly patients after surgery from June 2023 to February 2025.
A questionnaire was conducted and the individuals participating at the Syrian Private University were followed up during the research period. Accordingly, the questionnaire was filled out and the data was reviewed under the supervision of the research supervisor
Results
The sample included 240 patients, of which 20 were excluded, leaving us with 220 cases on which research and statistics were conducted. 39.5% were females and 60.5% were males. Participants are classified into five age groups, with the age group (20 – 21) years representing 24.1% (mean 76 years), and participants in the age group (22 – 23) were 50%.
79.5% of students believed that advanced age was a risk factor for septic shock.
Conclusion
It is necessary to hold medical seminars on sepsis and explain the difference between its types, as well as publish awareness campaigns on the necessity of educating medical staff, especially students, doctors, and nurses, about sepsis, its types, and ways to deal with it.
Bioconvective Flow of Eyring-Powell Nanofluid Over an Exponentially Sheet
Authors: Ali Muhammad Hussain , Irshad Sadia , Jahan Shah , Ahmad Muhammad 
Published: April 2024

Abstract

The focus of this study is to analyzed the 2-dimensional bioconvective flow of Eyring-Powell nanofluid over an exponentially stretching sheet is investigated numerically. Connective boundary conditions for both heat and mass transfer are employed. The governing highly nonlinear partial differential equations are converted into ordinary differential equations by using a similarity transformation. Numerical solutions of the nonlinear ordinary differential equations are found by bvp4c method in MATLAB software. Effects of Eyring-Powell fluid parameter ϵ and δ, Magnetic parameter M, Thermophoresis variable N_t, Lewis number L_b, Peclet number Pe and concentration difference of microorganismsω on velocity, temperature, concentration and motile density profiles are discussed. The nondimensional velocity of the nanofluid is increased as the significance of Eyring-Powell fluid parameter ϵ increases. By increasing the thermophoresis parameter N_t results in increasing profiles of temperature, concentration and motile. The motile profile decreases as the values of Peclet number Pe increases. The motile profile decreases with the rising values of microorganism’s concentration difference ω. Numerical evaluations of the skin friction coefficient, Nusselt numbers and Sherwood numbers are turbulated.
Identification of dual inhibitors for EGFR(T790M/C797S) and VEGFR-2 in Non-Small Cell Lung Cancer from Moringa oleifera derived phytochemicals: An In-silico Approach
Authors: Munna Md. Masudur Rahman , Tusar Md. Touki Tahamid , Shanta Saima Sajnin , Ahmed Md. Hossain , Ali Md. Sarafat 
Published: April 2024

Abstract

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related mortality on a global scale for both men and women. At present, the treatment of NSCLC involves the use of tyrosine kinase inhibitors (TKIs), which specifically target EGFR. However, resistance mechanisms like the emergence of T790M and C797S EGFR mutations and increased expression of VEGFR-2 often impede the efficacy of various generations of TKIs. Thus, EGFR and VEGFR-2 offer a great opportunity to treat NSCLC through the development of multi-targeted drugs. Our study aims to identify potential inhibitors by thoroughly evaluating the biological activity of M. oleifera-derived compounds that could serve as novel dual inhibitors of EGFR(T790M/C797S) and VEGFR-2, resulting in a synergistic inhibitory effect on these signaling pathways. We identified five potential phytocompounds from M. oleifera (hesperetin, gossypetin, quercetagetin, gallocatechin, and epigallocatechin) that showed significant binding affinity in virtual screening and multi-stage molecular docking analysis with remarkable drug-likeness and ADMET properties. These selected drug candidates also strongly bound and stayed stable with the receptors during the 200 ns MD simulation and MM-GBSA calculation. These findings indicate that these therapeutic candidates have the capacity to precisely target both EGFR and VEGFR-2 and can potentially act on both of these pathways as a single agent.
Economic and emotional impact of cataract surgery on patients by gender in Honduras
Authors: Ethridge Britton , Barber Kevin , O’Connor Sara 
Published: April 2024

Abstract

Purpose: To explore the economic and mental-health changes by gender following cataract surgery in Comayagua, Honduras.
Methods: This was a prospective, cohort survey-based study of 75 patients undergoing cataract surgery in March 2023 in Comayagua, Honduras. Surveys were completed in-person prior to surgery and by telephone four months postoperative. Economic questions included the Simple Poverty Scorecard tailored to Honduras, questions on work, and the effect of vision impairment on work. Mental health questions included the Patient Health Questionnaire-9 to assess depression, and the Generalized Anxiety Disorder-7 to assess anxiety.
Results: Income group increased in the whole cohort (1.81 to 2.53, p<0.005), among women (1.66 to 2.53, p=0.001) and when controlled for age and gender (ß=0.69, p<0.001). Participants were more likely to work outside the home following cataract surgery (17% to 37%, p=0.03). Anxiety scores increased among the whole cohort at follow-up, among women, and when controlled for age and gender. A significant proportion of participants (75%) reported that vision continued to interfere with their ability to work following cataract surgery.
Conclusion: Cataract surgery had the anticipated effects of increasing income and work outside the home. It also had the unanticipated effects of increasing anxiety scores and failure to restore vision that facilitates work. These results challenge assumptions about the impact of cataract surgery in the developing world, and indicate that further research into the economic and emotional impacts of eye care is needed.
Sweetening the deal: An infodemiological study of worldwide interest in semaglutide using Google Trends
Authors: RAUBENHEIMER Jacques Eugene , MYBURGH Pieter Hermanus , BHAGAVATH Akshaya Srikanth 
Published: April 2024

Abstract
Background: Off-label use of semaglutide for non-diabetic weight loss (presumably driven by social media) created world-wide supply shortages. We evaluated world-wide semaglutide interest measured by online search behavior to gauge social media and conventional print media reporting’s effect on search interest.
Methods: Using Google Trends Extended for Health multiple sampling, we retrieved regional online interest (ROI) for all countries and extracted timelines and top search queries for countries with median ROI≥20 for January 2021–August 2023 using the “semaglutide” topic. We obtained semaglutide media reporting from the ProQuest database. We estimated the effect of media and within-country semaglutide interest on between-country interest with Granger causality analysis. We determined changepoints for trends within each country with joinpoint regression. We determined prominent themes in search queries for each country with Natural Language Processing thematic analysis.
Results: Some countries showed increases in semaglutide interest. Granger analysis showed that media coverage could only partially explain interest, and interest in some countries partially preceded interest in others. Joinpoint analysis identified up to four significant within-country changepoints. One episode of the Dr Oz show (TV media event) drove strong peaks in numerous countries. Specific themes in top search queries showed some agreement between countries and country-specific themes. Weight loss was a major theme in most countries.
Conclusions: GTEH data provided insights into global search interest in semaglutide and regional variation. Studies focusing on specific countries which include social media data can elucidate specific drivers underlying the explosion in off-label use of semaglutide.
Comparison of Necrotizing Enterocolitis-related apoptosis factors in the ileum of lipopolysaccharide and hypoxia-treated full-term and pre-term rats
Authors: Lee Hye Rim , Ko Da Young , Lee Kyeung Yeup , Kim So Young , Youn Joong Kee , Yang Hee Beom , Kim Hyun Young 
Published: April 2024

Abstract

The aim of this study was to determine whether endotoxin, hypoxia, and prematurity are risk factors for developing necrotizing enterocolitis (NEC), which was achieved by investigating the pathogenesis of necrotizing enterocolitis in rats. To this end, we used premature Sprague-Dawley (SD) rat pups delivered by cesarean section at a gestational age of 21 days (Pre-term group) as well as Full-term SD rat pups four days after birth (Full-term group). The pups were exposed to lipopolysaccharides (LPS) and hypoxia to induce necrotizing enterocolitis. It was seen that both Full- and Pre-term rats were resulted in necrotizing enterocolitis. The results indicated that, compared to the control groups, the degree of apoptosis was elevated in both the Pre-term and Full-term NEC rats. The Full-term group also showed a reduction in Bcl-2 levels and an elevation in the ratio of Bax-to-Bcl-2 levels compared to the control group. Meanwhile, the Pre-term group showed a significantly increased expression level of RIPK1, which implies the induction of RIPK1-dependent apoptosis. This suggests that the pathophysiology of necrotizing enterocolitis induced by LPS+ hypoxia is associated with programmed cell death pathway. It appears that the apoptotic pathway of the Bax/Bcl-2 system is the main mechanism in Full-term rats. By contrast, a number of other mechanisms, including TNF-induced apoptosis mechanism, may work together for necrotizing enterocolitis development in Pre-term rats. Further studies are needed to elucidate the different pathogenesis of necrotizing enterocolitis development between Pre-term and Full-term rats.
Revisiting weight gain during gestation: body mass index and weight gain are associated with increased maternal cholesterol levels and higher risk of maternal supraphysiological hypercholesterolemia
Authors: Contreras-Duarte Susana , Moya Daniela , Parra Ricardo , Rotarou Elena S. , Leiva Andrea 
Published: April 2024

Abstract

Background
Total cholesterol (TC) and low-density lipoproteins (LDL) increase during pregnancy, in order to ensure fetal development. However, some women present maternal supraphysiological hypercholesterolemia (MSPH), or lipid levels over the 75th percentile, in the third trimester of pregnancy (T3). Despite this condition being associated with vascular dysfunction in the mother and the offspring, clinical reference values for lipid levels in pregnancy, and the impact of nutritional status on lipid profile – from pre-gestational (PG) until postpartum period (PP) – or on the onset of MSPH are unknown.
Aim
To determine if lipid levels at PG, pregnancy, and PP are influenced by maternal nutritional status, including body mass index (BMI) and weight gain during pregnancy (WG), and if these factors are associated with MSPH.
Methods
This study included data from 650 women categorized as normal weight (NW), overweight (OW), and with obesity (OB), according to the nutritional status, considering the BMI at T1. Lipid profiles (TC, LDL, HDL, and triglycerides (TG)) were analyzed at PG, T1, T2, T3, and PP. The percentiles for the different lipids and nutritional status were estimated. Correlations, and linear and logistic regressions were performed, considering lipids and weight parameters. Estimated probabilities for MSPH were also calculated.
Results
All women in our sample presented increased TC, LDL, and TG at T2, T3, and PP, in comparison to PG. Regarding nutritional status, women with OB presented reduced TC and LDL levels at T3 compared to NW women. TC and LDL at T3 were negatively correlated and associated with BMI at T3, while they were positively correlated and associated with WG. The logistic regression showed that WG is positively associatd with MSPH. Furthermore, the increase in WG is associated with an increased estimated probability for a woman having MSPH, and reaches 68.7% for a 30-kg WG.
Conclusion
The TC and LDL levels at T3 were directly related to weight parameters, and higher WG increased the risk for MSPH.
Performance, Analysis and Evaluation of UWOC Systems using OptiSystem Simulations across Diverse Water Conditions
Authors: P Latha , M Sreenithi K 
Published: April 2024

Abstract
The significance of underwater wireless communication continues to grow, driven by its diverse applications in both military operations and scientific research. This technology fills crucial gaps, particularly in scenarios where wired connections are impractical, such as submerged vehicles and devices. While acoustic communication dominates the field, its limitations in bandwidth and capacity necessitate the exploration of complementary technologies like underwater wireless optical communication (UWOC). This paper explores the simulation of a UWOC system using Optisystem software to assess its performance across various underwater mediums. The study encompasses three types of seawater: pure seawater, Coastal Ocean, and turbid harbor. Employing intensity modulation via a Mach-Zehnder Modulator and Laser Diode as the light source, the simulation evaluates the system's capabilities over different wavelengths within the visible light spectrum. Results demonstrate significant differences in transmitting distance and power consumption between wavelengths at the onset of the visual spectrum and those with minimal attenuation. Notably, in clear ocean water, a signal traverses over 100 meters (about 328.08 ft) with 1 mW, while leveraging different wavelengths yields a 65% power saving at the same distance. This research underscores the potential of UWOC in enhancing underwater communication efficiency and reliability.
Seeing through flames with one pixel
Authors: Zhang Zibang , Deng Zilin , Xiong Siming , Wang Qianlong , Zheng Guoan , Chang Huibin , Liu Haifeng , Zhong Jingang 
Published: April 2024

Abstract
Seeing through flames is a critical capability in various applications, such as fire rescue, industrial combustion monitoring, and scientific research. However, the intense electromagnetic radiation emitted by flames can saturate and blind conventional imaging systems, making it challenging to visualize objects or scenes obscured by fire. In this paper, we present a novel method for real-time, full-color through-flame imaging using structured illumination and single-pixel detection. By projecting a series of carefully designed light patterns onto the scene and measuring the backscattered light with a single-pixel detector, we can computationally reconstruct the obscured scene while effectively suppressing the flame's contribution to the image. The single-pixel detector's high dynamic range and sensitivity enable it to capture the weak backscattered signal without being overwhelmed by the flame's intense radiation. We demonstrate the method's effectiveness in several experiments, showcasing its ability to image static and dynamic scenes through both steady and turbulent flames at a frame rate of 15 Hz. Furthermore, we show that the proposed method can be extended to full-color imaging by using three single-pixel detectors with different color filters. The results highlight the potential of this approach for enhancing visibility in fire-related scenarios and other challenging imaging conditions. We believe that the integration of this technology into augmented reality (AR) systems could provide firefighters and other users with valuable real-time visual information, improving situational awareness and decision-making in critical situations. With further advancements in single-pixel detector technology and computational imaging techniques, the proposed method could pave the way for more sophisticated and practical through-flame imaging solutions.
Exploring Stakeholder Perspectives on Supply Chain Sustainability in Renewable Energy Industries
Authors: Dewi Lutfiana 
Published: April 2024

Abstract
This qualitative research study explores stakeholder perspectives on supply chain sustainability within the renewable energy industry. Through in-depth interviews and thematic analysis, diverse viewpoints, challenges, and strategies to enhance sustainability practices in renewable energy supply chains are uncovered. Government agencies, industry associations, renewable energy companies, NGOs, investors, and local communities contribute their insights, reflecting on environmental impacts, social responsibility, economic viability, and stakeholder engagement. Key findings emphasize the importance of minimizing environmental footprints, promoting social inclusion, overcoming economic barriers, and fostering collaborative partnerships. Stakeholder engagement emerges as crucial for transparency, trust-building, and shared accountability, enabling collective action towards a more sustainable energy future. The study contributes valuable insights for policymakers, industry leaders, and practitioners to drive collaborative efforts and advance sustainability goals across renewable energy supply chains.
Attention-Guided Erasing for Enhanced Transfer Learning in Breast Abnormality Classification
Authors: Panambur Adarsh Bhandary , Bhat Sheethal , Yu Hui , Madhu Prathmesh , Bayer Siming , Maier Andreas 
Published: April 2024

Abstract
Purpose: Breast cancer remains one of the most prevalent cancers globally, necessitating effective early screening and diagnosis. This study investigates the effectiveness and generalizability of our recently proposed data augmentation technique, attention-guided erasing (AGE), across various transfer learning classification tasks for breast abnormality classification in mammography.
Methods: AGE utilizes attention head visualizations from DINO self-supervised pretraining to weakly localize regions of interest (ROI) in images. These localizations are then used to stochastically erase non-essential background information from training images during transfer learning. Our research evaluates AGE across two image-level and three patch-level classification tasks. The image-level tasks involve breast density categorization in digital mammography (DM) and malignancy classification in contrast-enhanced mammography (CEM). Patch-level tasks include classifying calcifications and masses in scanned film mammography (SFM), as well as malignancy classification of ROIs in CEM.
Results: AGE significantly boosts classification performance with statistically significant improvements in mean F1-scores across four tasks compared to baselines. Specifically, for image-level classification of breast density in DM and malignancy in CEM, we achieve gains of 2% and 1.5%, respectively. Additionally, for patch-level classification of calcifications in SFM and CEM ROIs, gains of 0.4% and 0.6% are observed, respectively. However, marginal improvement is noted in the mass classification task, indicating the necessity for further optimization in tasks where critical features may be obscured by erasing techniques.
Conclusion: Our findings underscore the potential of AGE, a dataset- and task-specific augmentation strategy powered by self-supervised learning, to enhance the downstream classification performance of deep learning models, particularly involving Vision Transformers, in medical imaging.
Innovative Behavior Inventory and Innovation Support Inventory: Translation and validation in Greek
Authors: Moisoglou Ioannis , Katsiroumpa Aglaia , Kolisiati Antigoni , Tsiachri Maria , Tsakalaki Anastasia , Galanis Petros 
Published: April 2024

Abstract
Background
Innovative behavior and innovation support should be measured with valid tools to better understand employees’ attitudes.
Aim
To translate and validate the “Innovative Behavior Inventory” (IBI) and the “Innovation Support Inventory” (ISI) in Greek.
Methods
Our sample included 328 nurses in Greece. We performed our study during April 2024. We employed the forward-backward method to translate and adapt the IBI and the ISI in Greek language. We examined the construct validity of the scales by performing confirmatory factor analysis. We examined the concurrent validity of the scales using the “Quiet Quitting Scale” (QQS) and the single item burnout measure. We examined the reliability of the scales by calculating Cronbach’s alpha.
Results
IBI and ISI showed very good psychometric properties. Our confirmatory factor analysis confirmed the six-factor structure of the IBI and the three-factor structure of the ISI. Concurrent validity of the Greek versions of IBI and ISI was very good. We found statistically significant correlations between IBI and QQS (r = -0.540, p < 0.001), and single item burnout measure (r = -0.198, p < 0.001). We found statistically significant correlations between ISI and QQS (r = -0.313, p < 0.001), and single item burnout measure (r = -0.242, p < 0.001). Moreover, Cronbach’s coefficient alpha for all factors of IBI and ISI was higher than the acceptable cut-off of 0.700.
Conclusions
The Greek versions of the “Innovative Behavior Inventory” and the “Innovation Support Inventory” are reliable and valid tools to measure innovative behavior, innovation support and innovation outputs among workers.