bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of target composition on proton acceleration by intense laser pulses in the radiation pressure acceleration regime
Authors: Pae K.H. , Choi I.W. , Lee J. 
Published: January 2011

AbstractThe characteristics of high energy protons generated from thin carbon-proton mixture targets via circularly polarized intense laser pulses are investigated using two-dimensional particle-in-cell simulations. It is found that the density ratio n between protons and carbon ions plays a key role in determining the acceleration dynamics. For low n values, the protons are mainly accelerated by the radiation pressure acceleration mechanism, resulting in a quasi-monoenergetic energy spectrum. The radiation pressure acceleration mechanism is enhanced by the directed-Coulomb-explosion of carbon ions which gives a high proton maximum energy, though a large energy spread, for high n values. From a proton acceleration point of view, the role of heavy ions is very important. The fact that the proton energy spectrum is controllable based on the target composition is especially useful in real experimental environments.
Interdisciplinarity in the environmental sciences: barriers and frontiers
Authors: HICKS CHRISTINA C. , FITZSIMMONS CLARE , POLUNIN NICHOLAS V. C. 
Published: January 2011

SUMMARYGlobal environmental changes present unprecedented challenges to humans and the ecosystems upon which they depend. The need for interdisciplinary approaches to solve such multidimensional challenges is clear, however less clear is whether current attempts to cross disciplinary boundaries are succeeding. Indeed, efforts to further interdisciplinary approaches remain hampered by failures in assessing their scope and success. Here a set of measures examined the interdisciplinarity of the environmental sciences and tested two literature-based hypotheses: (1) newer and larger disciplines are more interdisciplinary; and (2) interdisciplinary research has lower impact factors than its counterparts. In addition, network analysis was used to map interdisciplinarity and determine the relative extent to which environmental science disciplines draw on alternative disciplinary perspectives. Contrary to expectations, age and size of a discipline had no effect on measures of interdisciplinarity for papers published in 2006, though metrics indicated larger articles and journals were more interdisciplinary. In addition, interdisciplinary research had a greater impact factor than its more strictly disciplinary peers. Network analysis revealed disciplines acting as ‘interdisciplinary frontiers’, bridging critical gaps between otherwise disparate subject areas. Whilst interdisciplinarity is complex, a combination of diversity metrics and network analysis provides valuable preliminary insights for interdisciplinary environmental research policy. The successful promotion of interdisciplinarity is needed to help dispel commonly perceived barriers to interdisciplinarity and create opportunities for such work by increasing the space available for different disciplines to encounter each other. In particular, the networks presented highlight the importance of considering disciplinary functioning within the wider context, to ensure maximum benefit to the scientific community as a whole.
Contamination level and ingestion dose of foodborne pathogens associated with infections
Authors: HARA-KUDO Y. , TAKATORI K. 
Published: January 2011

SUMMARYIntake of a small dose of foodborne pathogens can cause infection. In this study, an estimation of the infectious dose of the pathogens was obtained by conducting microbiological risk assessments. The contamination levels of foodborne pathogens were analysed in 17 outbreaks of Salmonella, Escherichia coli O157, enterotoxigenic E. coli, Vibrio parahaemolyticus, and Campylobacter jejuni occurring in Japan between 2004 and 2006. The infectious dose was estimated in 14 of the 17 outbreaks utilizing existing data. In three outbreaks of Salmonella infection in which the infection rate was 89–100%, the dose of the ingested pathogens was estimated to be 259 000–14 000 000 000 c.f.u. In other outbreaks of Salmonella infection, the infection rate and dose of the ingested pathogens were 10–66·4% and 81–1560 c.f.u. or most probable number (MPN), respectively. The ingested Salmonella dose is likely to be related to the infection rate; however, storage conditions should be taken into account when making this determination. In an outbreak of E. coli O157 infection, the infection rate and ingestion dose were 100% and 2 to <9 c.f.u., respectively, while in an outbreak of enterotoxigenic E. coli infection, they were 93% and 25–1000 c.f.u., respectively. Finally, in an outbreak of C. jejuni infection, the infection rate and ingestion dose were 37·5% and 360 MPN, respectively. These results will be particularly valuable for risk assessment.
Stem cells in stroke management
Authors: Muir Keith W 
Published: January 2011

SummaryStem cells are a potential means of tissue regeneration in the brain that hold promise for treatment of the large number of stroke survivors who have permanent disability. Animal studies with stem cells derived from many different sources indicate that cells can migrate to the site of ischaemic injury in the brain, and that some survive and differentiate into neurones and glia with evidence of electrical function. Cells additionally promote endogenous repair mechanisms, including mobilization of neural stem cells resident within the adult brain. Whether the behavioural benefits seen with stem cell administration in rodent models reflect enhanced endogenous recovery or tissue regeneration is unclear. Production of stem cells to clinical standards and in quantities required for clinical studies is technically challenging. To date only a handful of patients have been involved in preliminary clinical studies of cell therapies for stroke, and there are therefore insufficient data to draw conclusions about either safety or efficacy. Further trials with several cell types are ongoing or planned, including neural stem cells, and bone marrow-derived stem cells and endothelial progenitor cells.
Brycon gouldingi(Teleostei, Characidae): aspects of the embryonic development in a new fish species with aquaculture potential
Authors: Faustino Francine , Nakaghi Laura Satiko Okada , Neumann Erika 
Published: January 2011

SummaryBrycon gouldingiis an endemic species from Tocantins-Araguaia basin, used as a food source by riverine communities and relevant to aquaculture. Information about the initial morphology ofB. gouldingi, a recently described species, is absent. In the present study, we analysed the fertilization and the embryonic development of this species based on light and scanning electron microscopy. After collection of adult specimens in Mortes River – Mato Grosso, Brazil, adaptation to captivity and induced spawning at Buriti Fishculture, Nova Mutum – Mato Grosso, Brazil, in December 2007 and January 2008, samples were collected at pre-defined periods from egg extrusion up to larval hatching, which occurred at 13.9 ± 0.06 h post-fertilization (hpf) in average. At the moment of extrusion, the eggs were slightly ovoid bearing a single micropyle per oocyte with a funnel-shaped micropyle canal and vestibule covered with longitudinal folds, typical of the genusBrycon. The embryonic development ofB. gouldingiwas characterized by six stages with distinct features: zygote (from fertilization up to formation of egg-cell); cleavage (cell divisions resulting in blastomeres, including the morula phase); blastula (several embryonic cells in a cup shape, without distinction of cell boundaries); gastrula (cell movement); histogenesis/organogenesis (formation of tissues and organs); and hatching (larval chorion rupture). Right after hatching, the larvae presented neither swimming abilities nor visual accuracy, and the digestive trait was undifferentiated. The present study is the first report on biological features of embryogenesis inB. gouldingi, providing relevant information to several approaches, mainly related to taxonomy, ecology, conservation and captive rearing of this newBryconspecies.
Educational achievement among long-term survivors of congenital heart defects: a Danish population-based follow-up study
Authors: Olsen Morten , Hjortdal Vibeke E. , Mortensen Laust H. , Christensen Thomas D. , Sørensen Henrik T. , Pedersen Lars 
Published: January 2011

AbstractBackgroundCongenital heart defect patients may experience neurodevelopmental impairment. We investigated their educational attainments from basic schooling to higher education.Patients and methodsUsing administrative databases, we identified all Danish patients with a cardiac defect diagnosis born from 1 January, 1977 to 1 January, 1991 and alive at age 13 years. As a comparison cohort, we randomly sampled 10 persons per patient. We obtained information on educational attainment from Denmark's Database for Labour Market Research. The study population was followed until achievement of educational levels, death, emigration, or 1 January, 2006. We estimated the hazard ratio of attaining given educational levels, conditional on completing preceding levels, using discrete-time Cox regression and adjusting for socio-economic factors. Analyses were repeated for a sub-cohort of patients and controls born at term and without extracardiac defects or chromosomal anomalies.ResultsWe identified 2986 patients. Their probability of completing compulsory basic schooling was approximately 10% lower than that of control individuals (adjusted hazard ratio = 0.79, ranged from 0.75 to 0.82 0.79; 95% confidence interval: 0.75–0.82). Their subsequent probability of completing secondary school was lower than that of the controls, both for all patients (adjusted hazard ratio = 0.74; 95% confidence interval: 0.69–0.80) and for the sub-cohort (adjusted hazard ratio = 0.80; 95% confidence interval: 0.73–0.86). The probability of attaining a higher degree, conditional on completion of youth education, was affected both for all patients (adjusted hazard ratio = 0.88; 95% confidence interval: 0.76–1.01) and for the sub-cohort (adjusted hazard ratio = 0.92; 95% confidence interval: 0.79–1.07).ConclusionThe probability of educational attainment was reduced among long-term congenital heart defect survivors.
Outcomes of cardiac surgery in trisomy 18 patients
Authors: Muneuchi Jun , Yamamoto Junko , Takahashi Yasuhiko , Watanabe Mamie , Yuge Tetsuji , Ohno Takuro , Imoto Yutaka , Sese Akira , Joo Kunitaka 
Published: January 2011

AbstractObjectiveThe objective was to clarify the outcomes of cardiac surgery in trisomy 18 patients.Patients and methodsWe analysed 34 consecutive trisomy 18 patients, of whom 21 were males, with cardiac complications. They were divided into patients who underwent cardiac surgery and those who were conservatively treated. We compared rates of survival and discharge alive between two groups.ResultsThe surgery group included nine patients, with six males, who underwent cardiac surgery – intracardiac repair in three patients, pulmonary arterial banding in five patients, and ligation of the ductus in one patient – at median age of 2.2 months, ranging from 0.5 to 9.8, and with median weight of 2.6 kilograms, ranging from 1.5 to 3.2. Cardiac surgery and pre-operative assisted ventilation were hazardous factors leading to death. In the surgery group, cumulative survival rates at 1 month, 6 months, 12 months, and 24 months were 63%, 38%, 25%, and 22%, respectively, compared with 51%, 26%, 9%, and 9% in the conservative group. There was a significant difference (p = 0.002). The cumulative rates of discharge alive at 1 month, 3 months, and 6 months were 0%, 12%, and 65% in the surgery group, which did not differ from the conservative group (p = 0.80).ConclusionsCardiac surgery contributed to increased survival rate but not the rate of discharge alive in trisomy 18 patients. Cardiac surgery could not prevent all the trisomy 18 patients from death. The indication of cardiac surgery should be carefully individualised to improve the quality of life in trisomy 18 patients and concerned surrounding people.
The Fate of the 0.5s: Predictors of 2-Year Outcome in Mild Cognitive Impairment
Authors: Aretouli Eleni , Okonkwo Ozioma C. , Samek Jaclyn , Brandt Jason 
Published: January 2011

AbstractImpairments in executive cognition (EC) may be predictive of incident dementia in patients with mild cognitive impairment (MCI). The present study examined whether specific EC tests could predict which MCI individuals progress from a Clinical Dementia Rating (CDR) score of 0.5 to a score ≥1 over a 2-year period. Eighteen clinical and experimental EC measures were administered at baseline to 104 MCI patients (amnestic and non-amnestic, single- and multiple-domain) recruited from clinical and research settings. Demographic characteristics, screening cognitive measures and measures of everyday functioning at baseline were also considered as potential predictors. Over the 2-year period, 18% of the MCI individuals progressed to CDR ≥ 1, 73.1% remained stable (CDR = 0.5), and 4.5% reverted to normal (CDR = 0). Multiple-domain MCI participants had higher rates of progression to dementia than single-domain, but amnestic and non-amnestic MCIs had similar rates of conversion. Only three EC measures were predictive of subsequent cognitive and functional decline at the univariate level, but they failed to independently predict progression to dementia after adjusting for demographic, other cognitive characteristics, and measures of everyday functioning. Decline over 2 years was best predicted by informant ratings of subtle functional impairments and lower baseline scores on memory, category fluency, and constructional praxis. (JINS, 2011,17, 277–288)
Diverging opinions of supplementation programmes between mothers of small children and staff at primary health clinics in the Western Cape Province of South Africa
Authors: Iversen Per O , Høisæther Elisabeth A , Morseth Marianne , Herselman Marietjie 
Published: January 2011

AbstractObjectiveNutritional status has remained inadequate among disadvantaged mothers and small children in South Africa. Several supplementation programmes are administered through primary health clinics (PHC). The present study examined the perceptions of mothers who attend PHC and of the PHC staff on the purpose, management and eligibility of the vitamin A and nutritional supplementation components of the Nutrition Supplementation Programme (NSP).DesignObservational study based on anthropometry and questionnaires.SettingRandom selection of ten urban and ten rural PHC from the Western Cape Province of South Africa.SubjectsMothers (n 176) and their children (n 179) aged <5 years, and various PHC staff categories.ResultsHalf (56 %) of the households were classified as food insecure and about one-third of the children were malnourished, as evidenced by stunting, wasting or underweight. A majority of mothers complained about poor information related to the programmes. More than half of the children who were eligible for NSP were not included. In contrast, the staff felt that they managed both programmes well and problems with implementation were mostly attributed to clients.ConclusionsIn general, the mothers expressed more dissatisfaction and ignorance about the vitamin A programme and the NSP than was perceived by the staff. This apparent discrepancy might, at least in part, explain why these programmes do not work optimally.
Socio-economic differences in outdoor food advertising in a city in Northern England
Authors: Adams Jean , Ganiti Ellie , White Martin 
Published: January 2011

AbstractObjectiveTo explore differences in the prevalence of outdoor food advertising, and the type and nutritional content of advertised foods, according to an area-based marker of socio-economic position (SEP) in a city in Northern England.DesignAll outdoor advertisements in the city were identified during October–December 2009, their size (in m2) estimated and their location determined using a global positioning system device. Advertisements were classified as food or non-food. Food advertisements were classified into one of six food categories. Information on the nutritional content of advertised foods was obtained from packaging and manufacturer's websites. An area-based marker of SEP was assigned using the location of each advertisement, grouped into three affluence tertiles for analysis.SettingA city in Northern England.SubjectsNone.ResultsIn all, 1371 advertisements were identified; 211 (15 %) of these were for food. The advertisements covered 6765 m2, of which 1326 m2 (20 %) was for food. Total advertising and food advertising space was largest in the least affluent tertile. There was little evidence of socio-economic trends in the type or nutritional content of advertised foods.ConclusionsDespite an absence of socio-economic differences in the type and nutritional content of advertised foods, there were socio-economic differences in food advertising space. There may also be socio-economic differences in exposure to outdoor food advertising.
Healthy food availability and participation in WIC (Special Supplemental Nutrition Program for Women, Infants, and Children) in food stores around lower- and higher-income elementary schools
Authors: Tester June M , Yen Irene H , Pallis Lauren C , Laraia Barbara A 
Published: January 2011

AbstractObjectiveThe nutritional intake of schoolchildren is affected not only by what is consumed at school but also by what is available in food outlets near schools. The present study surveys the range of food outlets around schools and examines how the availability of healthy food in the food stores encountered varies by income status of the school and by store participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) food assistance programme.DesignNetwork buffer zones were created to reflect a quarter-mile (400 m) walk from elementary schools with lower- and higher-income student populations in Oakland, CA, USA. All food outlets within these zones were categorised by type, and audits were conducted within food stores using a checklist to assess for the presence or absence of twenty-eight healthy items (in five domains).SettingMid-sized city in the USA.SubjectsFood outlets near public elementary schools.ResultsThere were considerably more food outlets around lower-income schools. Food stores near higher-income schools had higher scores in two of the five domains (healthy beverages/low-fat dairy and healthy snacks). However, there were more food stores near lower-income schools that accepted WIC vouchers. Stratification showed that WIC stores scored higher than non-WIC stores on four of the five domains.ConclusionsAlthough higher-income students have more access to healthy food in the environment surrounding their school, this disparity appears to be mitigated by stores that accept WIC and offer more healthy snacking options. Federal programmes such as this may be particularly valuable for children in lower-income areas.
COMPARISON OF NUMERICAL AND ANALYTICAL APPROXIMATIONS OF THE EARLY EXERCISE BOUNDARY OF AMERICAN PUT OPTIONS
Authors: LAUKO M. , ŠEVČOVIČ D. 
Published: January 2011

AbstractWe present qualitative and quantitative comparisons of various analytical and numerical approximation methods for calculating a position of the early exercise boundary of American put options paying zero dividends. We analyse the asymptotic behaviour of these methods close to expiration, and introduce a new numerical scheme for computing the early exercise boundary. Our local iterative numerical scheme is based on a solution to a nonlinear integral equation. We compare numerical results obtained by the new method to those of the projected successive over-relaxation method and the analytical approximation formula recently derived by Zhu [‘A new analytical approximation formula for the optimal exercise boundary of American put options’, Int. J. Theor. Appl. Finance9 (2006) 1141–1177].
FIELDS AND VISIONS
Authors: Rosbrook-Thompson James , Armstrong Gary 
Published: January 2011

AbstractThe concept of the “African Personality” was celebrated by the continent's first post-colonial President, Kwame Nkrumah. Sweeping to power in Ghana's first general election in 1951, Nkrumah and his Convention People's Party—inspired by Marcus Garvey and W. E. B. Du Bois—espoused the doctrines of nationhood and self-reliance. The conceptual dimensions of Nkrumah's “African Personality” and the role he had in mind for Association Football (soccer) as an instrument of its expression are crucial points of this analysis. Here we attempt to locate Nkrumah's political ideal within the contemporary realities of the migration of young Ghanaian soccer talent, examining at the same time the socio-economic processes which act as “push” and “pull” mechanisms in the context of such migratory trends. While Nkrumah's “race-conscious,” pan-African forces have been utilized in the face of post-colonial identifications, soccer loyalties and objectives which are far more immediate and parochial in character continue to supersede those surrounding national or “racial” interests. Ghana's domestic game and national selection are riven by ethnic and regional hostilities while interlopers from Europe—some acting alone, others as emissaries for European soccer clubs—have laid down roots in Ghana, recognizing the nation as a breeding ground for talented, and comparatively cheap, young soccer talent. We argue that such inveterate ethno-regional rivalries, along with the conditions of neoliberal capitalism and its instrumental system of uneven geographical development, have provided entry points for the post-colonial forces so maligned by Nkrumah. Furthermore, we question the wisdom of notions of belonging based on bounded units such as “race” and attendant expressions of “race-consciousness.”
Essential multiple functions of farms in rural communities and landscapes
Authors: Milestad Rebecka , Ahnström Johan , Björklund Johanna 
Published: January 2011

AbstractAs farms are consolidated into larger operations and small farms close down for economic reasons, rural areas lose ecological, social and economic functions related to farming. Biodiversity and scenic, open-vista landscapes are lost as fields are left unmanaged. Social and economic benefits such as local job opportunities and meeting places disappear. Four Swedish rural communities were examined to increase our understanding of the functions that a diverse agriculture provides and which of these are lost as farms cease operation and overall rural social capital is depleted. Workshops and interviews with village action groups and with farmers were carried out. Both groups identified key functions from farming that are important to the rural community, such as production of food and fiber, businesses and jobs, human services, local security, ecosystem services such as nutrient cycling and biodiversity, and functions pertaining to quality of life. Several ways in which village action groups can support agriculture were identified that current industrial agriculture and even agri-environmental schemes fail to achieve. These include organizing local meeting places, encouraging local processing and consumption and supporting farmers in their work. We conclude that agriculture and village action groups match well in community development and that policies supporting this match would be useful.