bluuebunny/crossref_metadata_2025_split huggingface dataset:
A blockchain‐based and microservices‐architected software composition analysis system
Authors: Zhou Xin , Xu Jinwei , Li Xiaokang , Cao Lingli , Li Lingjie , Wang Yanze , Li Shanshan , Liu Hui 
Published: June 2024

Abstract“Shift To Left” is the cornerstone of the successful implementation of DevSecOps. By testing projects for vulnerabilities in the early stages of development, teams can save overall costs before security issues reach the build phase. As one of the popular practices in “Shift To Left,” the Software Composition Analysis (SCA) system aims to leverage the Software Bill of Materials (SBOM) to enhance software supply chain security. However, the SBOM lacks mature generation and distribution mechanisms, requiring incentive measures to drive industry consensus. Additionally, the data and tools associated with the SBOM lack effective record‐keeping and monitoring, making it challenging to ensure data integrity and tool security. Traditional SCA systems treat SBOM as a regular data format for external service provision, yet fail to solve problems such as lack of shared platforms, inability to guarantee data integrity and tool security, as well as issues with poor interoperation compatibility. This paper introduces blockchain technology into the SCA system, utilizing smart contracts to provide core SBOM tool services and microservices to improve the operational efficiency of smart contract deployment and maintenance. The proposed SCA system effectively provides a shared platform for SBOM with reliable data integrity, guaranteed tool security, and good interoperability.
Comprehensive molecular evolutionary analysis of small heat shock proteins in five diploid Gossypium species
Authors: Fan Kai , Qian Zhengyi , He Yuxi , Chen Jiayuan , Ye Fangting , Zhu Xiaogang , Lin Wenxiong , Cui Lili , Lan Tao , Li Zhaowei 
Published: June 2024

AbstractThe small heat shock proteins (sHSPs) are important components in plant growth and development, and stress response. However, a systematical understanding of the sHSP family is yet to be reported in five diploid Gossypium species. In this study, 34 GlsHSPs, 36 GrsHSPs, 37 GtsHSPs, 37 GasHSPs, and 38 GhesHSPs were identified in Gossypium longicalyx, Gossypium raimondii, Gossypium turneri, Gossypium arboreum, and Gossypium herbaceum, respectively. These sHSP members can be clustered into 10 subfamilies. Different subfamilies had different member numbers, motif distributions, gene structures, gene duplication events, gene loss numbers, and cis‐regulatory elements. Besides, the paleohexaploidization event in cotton ancestor led to expanding the sHSP members and it was also inherited by five diploid Gossypium species. After the cotton ancestor divergence, the sHSP members had the relatively conserved evolution in five diploid Gossypium species. The comprehensive evolutionary history of the sHSP family was revealed in five diploid Gossypium species. Furthermore, several GasHSPs and GhesHSPs were important candidates in plant growth and development, and stress response. These current findings can provide valuable information for the molecular evolution and further functional research of the sHSP family in cotton.
‘Living Well and Teaching Well’: Exploring How Beginning Teachers Enact Good Pedagogical Praxis in Their Everyday Practices in Historically Hard-to-Staff Schools
Authors: Garoni Stephanie , Lampert Jo , Hoff Lutz 
Published: June 2024

AbstractThe notion of pedagogical praxis underpins the work of La Trobe University’s Nexus program: a social justice oriented, alternative pathway into secondary teaching for historically hard-to-staff secondary schools in Victoria, Australia. This chapter maps the experiences of beginning teachers in the Nexus program as they live and work in a time of complexity and rapid change. It explores the meaning of ‘living well’ and its relationship to ‘teaching well’ through a practice lens, arguing that sometimes the enactment of ‘good pedagogical praxis’ can be difficult amidst the pressures associated with early career teaching. We use the theory of practice architectures to discuss these challenges as beginning teachers balance their commitment to creating socially just and equitable spaces for learning with the realities of contemporary schooling. We draw on stories from four Nexus teachers to examine the site-based arrangements that enable and constrain their ability to ‘teach well’. Ways in which they can enact morally and ethically informed practices while negotiating the changing conditions of their school environment are identified. This leads to a discussion of beginning teachers and a praxis-oriented view of pedagogy.
Potential of Students’ Voices to Contribute to Education for a Future World Worth Living In
Authors: Longmuir Fiona 
Published: June 2024

AbstractThis chapter examines the positioning and potential of students to contribute to the evolution of educational practices and arrangements that better reflect their needs and interests as they learn to be and become in a world worth living in for all. Historically, students’ voices are silenced through education with the imposition of schooling arrangements designed to meet the economic and social needs of the present. While students are often surrounded by messages that suggest their futures are in peril from environmental and social crises, their education remains confined to a focus on present imperatives. Although many educators are motivated to transform schooling, traditions and systemic objectives that hold conventional arrangements in place have proven to be difficult to disrupt. Bringing evidence from research that investigated the experiences of students who had disengaged from mainstream schooling in Melbourne, Australia, this chapter highlights possibilities for students to be seen as highly informed experts in their own education. I argue that along with enhancing student voice, a more explicit focus on a ‘capacity to aspire’ as a future-focused capability can counter limiting discourses that prevail and support students to shape a future world worth living in for all.
Democratic Practices with and for Our Youngest Citizens: Early Childhood Education, Agency, and the Education Complex
Authors: Salamon Andi , Gibbs Leanne , Cooke Mandy 
Published: June 2024

AbstractEarly childhood pedagogy in Australia is founded on rights-based philosophies that promote social justice, democratic communities, participation, and agency of societies’ youngest citizens. There are, however, significant challenges in realising these philosophies and enacting democratic, agentic early childhood education (ECE) for birth to five-year-old children. This chapter presents three research projects, viewed together through a lens of agency and aligned with the education complex (Kemmis et al., 2012), that highlight the interdependent practices of leading, teaching, and researching in Australian ECE contexts. The first project investigated the emergence and development of effective leadership practices and the arrangements that enabled and constrained them. The second project explored educators’ risk-taking practices, aligning with praxis as morally and ethically informed decision-making about what is ‘best’ for children and societies (Kemmis & Smith, 2008). The third project documented infants’ social and emotional communication and highlighted how the research practices helped enable infants’ participation and agency. Though the focus of each study was different, collectively they illuminate interdependent practices of an ‘ECE complex’, and how individual and collective agencies can optimise pedagogy with and for very young children to live well and help create a world worth living in (Kemmis et al., 2014).
Beschleunigte muskuloskeletale Magnetresonanztomographie mit Deep-Learning-gestützter Bildrekonstruktion bei 0,55 T–3 T
Authors: Vosshenrich Jan , Fritz Jan 
Published: June 2024

Zusammenfassung
Klinisches/methodisches Problem
Die Magnetresonanztomographie (MRT) ist ein zentraler Bestandteil der muskuloskeletalen Diagnostik. Lange Akquisitionszeiten können jedoch zu Einschränkungen in der klinischen Praxis führen.

Radiologische Standardverfahren
Die MRT hat sich aufgrund des hohen Auflösungsvermögens und Signal-zu-Rausch-Verhältnisses (SNR) sowie des exzellenten Weichteilkontrastes als Modalität der Wahl in der Diagnostik von Verletzungen und Erkrankungen des muskuloskeletalen Systems etabliert.

Methodische Innovationen
Kontinuierliche Weiterentwicklungen in der Hard- und Softwaretechnologie haben eine bildqualitäts- und genauigkeitsneutrale Beschleunigung von 2D-Turbo-Spin-Echo(TSE)-Sequenzen um den Faktor 4 ermöglicht. Kürzlich vorgestellte, auf Deep Learning (DL) basierende Bildrekonstruktionsalgorithmen helfen, die Abhängigkeit zwischen SNR, räumlicher Auflösung und Akquisitionszeit weiter zu minimieren und erlauben die Anwendung höherer Beschleunigungsfaktoren.

Leistungsfähigkeit
Die kombinierte Anwendung fortschrittlicher Beschleunigungstechniken und DL-basierter Bildrekonstruktion birgt enormes Potenzial, um die Effizienz, den Patientenkomfort und die Zugänglichkeit der muskuloskeletalen MRT bei gleichbleibend hoher diagnostischer Genauigkeit zu maximieren.

Bewertung
DL-rekonstruierte beschleunigte MRT-Untersuchungen haben ihre Praxisreife und ihren Mehrwert innerhalb kürzester Zeit unter Beweis gestellt. Aktuelle wissenschaftliche Erkenntnisse legen nahe, dass das Potenzial dieser Technologie noch nicht ausgeschöpft ist.

Empfehlung für die Praxis
Beschleunigte MRT-Untersuchungen mit DL-gestützter Bildrekonstruktion können zuverlässig in der Primärdiagnostik und Verlaufskontrolle muskuloskeletaler Fragestellungen eingesetzt werden.
The stability of government bond markets’ equilibrium and the interdependence of lending rates
Authors: Rodrigues Paulo M. M. , Sibbertsen Philipp , Voges Michelle 
Published: June 2024

AbstractIn this paper, we introduce test procedures for no fractional cointegration against possible breaks to a fractional cointegrating relationship in a segment of the data. We base the proposed tests on the supremum of the Hassler and Breitung (Econom Theor 22(6):1091–1111, 2006) test statistic for no cointegration over possible breakpoints in the long-run equilibrium. We show that the new tests correctly standardized converge to the supremum of a Chi-squared distribution and that this convergence is uniform. An in-depth Monte Carlo analysis provides results on the finite sample performance of our tests. We then use the new procedures to investigate whether there was a dissolution of fractional cointegrating relationships between the yields of government bonds of eleven EMU countries (Spain, Italy, Portugal, Ireland, Greece, Belgium, Austria, Finland, the Netherlands, Germany and France) as a consequence of the European debt crisis and to understand the degree of interdependence of lending rates to non-financial corporations across these eleven countries.
Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023
Authors: Neri Ilaria , Russo Giacomo , Grumetto Lucia 
Published: June 2024

AbstractIn this review article, the research works covering the analytical determination of bisphenol A (BPA) and its structural analogues published from 2018 to present (February 2024) were examined. The review offers an overview of the concentration levels of these xenoestrogens in food and beverages, and discusses concerns that these may possibly pose to the human health and scrutinises, from an analytical perspective, the main biomonitoring approaches that are applied. This comes as a natural evolution of a previous review that covered the same topic but in earlier years (up to 2017). As compared to the past, while the volume of published literature on this topic has not necessarily decreased, the research studies are now much more homogeneous in terms of their geographical origin, i.e., Southern Europe (mainly Italy and Spain). For this reason, an estimated daily intake of the European population could not be calculated at this time. In terms of the analytical approaches that were applied, 67% of the research groups exploited liquid chromatography (LC), with a detection that was prevalently (71%) afforded by mass spectrometry, with over one-fourth of the research teams using fluorescence (26%) and a minority (3%) detecting the analytes with diode array detection. One-third of the groups used gas chromatography (GC)–mass spectrometry achieving comparatively superior efficiency as compared to LC. Derivatisation was performed in 59% of the GC studies to afford more symmetrical signals and enhanced sensitivity. Although the contamination levels are well below the threshold set by governments, routinely biomonitoring is encouraged because of the possible accumulation of these contaminants in the human body and of their interplay with other xenoestrogens.
Comparative transcriptomic analysis of the nodulation-competent zone and inference of transcription regulatory network in silicon applied Glycine max [L.]-Merr. Roots
Authors: Mansoor Sheikh , Tripathi Pooja , Ghimire Amit , Hamid Saira , Abd El-moniem Diaa , Chung Yong Suk , Kim Yoonha 
Published: June 2024

Abstract
Key message
The study unveils Si's regulatory influence by regulating DEGs, TFs, and TRs. Further bHLH subfamily and auxin transporter pathway elucidates the mechanisms enhancing root development and nodulation.

Abstract
Soybean is a globally important crop serving as a primary source of vegetable protein for millions of individuals. The roots of these plants harbour essential nitrogen fixing structures called nodules. This study investigates the multifaceted impact of silicon (Si) application on soybean, with a focus on root development, and nodulation employing comprehensive transcriptomic analyses and gene regulatory network. RNA sequence analysis was utilised to examine the change in gene expression and identify the noteworthy differentially expressed genes (DEGs) linked to the enhancement of soybean root nodulation and root development. A set of 316 genes involved in diverse biological and molecular pathways are identified, with emphasis on transcription factors (TFs) and transcriptional regulators (TRs). The study uncovers TF and TR genes, categorized into 68 distinct families, highlighting the intricate regulatory landscape influenced by Si in soybeans. Upregulated most important bHLH subfamily and the involvement of the auxin transporter pathway underscore the molecular mechanisms contributing to enhanced root development and nodulation. The study bridges insights from other research, reinforcing Si’s impact on stress-response pathways and phenylpropanoid biosynthesis crucial for nodulation. The study reveals significant alterations in gene expression patterns associated with cellular component functions, root development, and nodulation in response to Si.

Graphical abstract
Re(de)fining degree-heating week: coral bleaching variability necessitates regional and temporal optimization of global forecast model stress metrics
Authors: Whitaker Hannah , DeCarlo Thomas 
Published: June 2024

AbstractTropical coral reefs are a critical ecosystem in global peril as a result of anthropogenic climate change, and effective conservation efforts require reliable methods for identifying and predicting coral bleaching events. To this end, temperature threshold-based models such as the National Oceanic and Atmospheric Administration’s (NOAA) degree-heating week (DHW) metric are useful for forecasting coral bleaching as a function of heat stress accumulation. DHW does not adequately account for regional variation in coral stress responses, however, and the current definition consistently underpredicts coral bleaching occurrence. Using a weather forecasting skill-based framework, our analysis cross-tested 1080 variations of the DHW-based bleaching occurrence (presence/absence) model against 22 years of contemporary coral bleaching observations (1998–2019) in order to optimize bleaching forecast skill at different levels of geographic specificity. On a global basis and relative to the current definition, reducing the current 1 °C warming cutoff to 0.4 °C, adjusting the accumulation window to 11 weeks, and defining a bleaching threshold of 3 DHW improved forecast skill by 70%. Allowing our new DHW definitions to vary across regions and ocean basins further doubled model skill. Our results also suggest that the most effective bleaching forecast models change over time as coral reef systems respond to a shifting climate. Since 1998, the coral bleaching threshold for the globally optimized forecast model has risen at a significant rate of 0.19 DHW/year, matching the pace of ocean warming. The bleaching threshold trajectory for each ocean basin varies. Though further work is necessary to parse the mechanism behind this trend, the dynamic nature of coral stress responses demands that our forecasting tools be continuously refined if they are to adequately inform marine conservation efforts.
Pharyngeal adaptation to bolus properties in patients with Parkinson’s disease
Authors: Saleem Shakeela , Miles Anna , Allen Jacqueline 
Published: June 2024

Abstract
Purpose
Dysphagia is common in people with Parkinson’s disease (PD). Yet, literature describing swallow function in PD using high-resolution manometry is limited. This study explored swallowing pressure metrics for varied bolus conditions in people with PD.

Method
A solid-state unidirectional catheter was used to acquire manometric data for triplicate swallows (5 ml, 10 ml, 20 ml; IDDSI 0, 2 & 4). Penetration-aspiration severity was rated during videofluoroscopy. Patient-reported measures included PDQ-8: Parkinson’s Disease Questionnaire-8 and EAT-10: Eating Assessment Tool-10. Quantitative manometric swallow analysis was completed through Swallow Gateway™. Metrics were compared to published normative values and generalized linear model tests explored modulatory effects.

Results
21 participants (76% male; mean age 69.6 years, SD 7.1) with mild-moderate severity PD were studied. Two patients (9%) aspirated for single bolus thin liquid and paste trials and 15 patients (73%) scored > 3 EAT-10. Standardized PDQ-8 scores correlated with EAT-10 (p < 0.05). Abnormality in UES relaxation and distension was demonstrated by high UES integrated relaxation pressure and low UES maximum admittance (UES MaxAdm) values across varied bolus conditions. Participants demonstrated abnormally elevated pharyngeal contractility and increased post-swallow upper-esophageal sphincter (UES) contractility for thinner liquid trials. Alterations in volume and viscosity had significant effects on the bolus timing metric—distention to contraction latency. UES peak pressure measures were altered in relation to bolus viscosity.

Conclusion
This study identifies early pharyngoesophageal contractile changes in relation to bolus volume and viscosity in PD patients, associated with subtle deterioration of self-reported swallow scores. Manometric evaluation may offer insight into PD-related swallowing changes and help optimize diagnostics and treatment planning
Treatment demand for cannabis use problems: analyses of routine data from 30 European countries
Authors: Manthey Jakob 
Published: June 2024

AbstractCannabis use and treatment demand has risen in the past decade. Previous analyses of treatment demand are limited by methodological constraints or are outdated. Cross-country differences and trends in cannabis treatment demand are described using data from the European Monitoring Centre for Drugs and Drug Addiction. Two novel indicators are employed: firstly, the cannabis-attributable treatment fraction (CATF) is obtained by dividing the number of treatment entrants for cannabis use problems by the number of treatment entrants for any substance use problem, accounting for possible changes in the reporting system. Secondly, comparing the number of treatment entrants for cannabis use problems to the number of people who use cannabis (near) daily yields the treated-user-ratio (TUR), which considers a proxy for treatment need (frequent use). Across 30 countries with available data, the importance of cannabis in European treatment facilities varies greatly (CATF: min = 3%; max = 65%), with lower estimates in Eastern European countries. Across 20 countries with complete data, the CATF has risen from 29.4% in 2013 to 37.1% in 2020. The TUR calculated on 26 countries suggests that about 3 in 100 frequent users have sought treatment for their cannabis use problems. Over time, treatment demand has increased at a slower pace than treatment need in most countries. One in three treatment entrants for substance use problems in Europe are due to cannabis, with large variations between countries. There are indications for a widening treatment gap for cannabis use problems. In countries liberalising cannabis laws, monitoring changes in treatment access and demand is warranted.
Pathological mechanisms and treatment of sporadic Parkinson’s disease: past, present, and future
Authors: Mochizuki Hideki 
Published: June 2024

AbstractFor a special issue, we review studies on the pathogenesis of nigral cell death and the treatment of sporadic Parkinson’s disease (sPD) over the past few decades, with a focus on the studies performed by Prof. Mizuno and our group. Prof. Mizuno proposed the initial concept that mitochondrial function may be impaired in sPD. When working at Jichi Medical School, he found a decrease in complex I of the mitochondrial electron transfer complex in the substantia nigra of patients with Parkinson’s disease (PD) and MPTP models. After moving to Juntendo University as a professor and chairman, he continued to study the mechanisms of cell death in the substantia nigra of patients with sPD. Under his supervision, I studied the relationships between PD and apoptosis, PD and iron involvement, mitochondrial dysfunction and apoptosis, and PD and neuroinflammation. Moving to Kitasato University, we focused on PD and the cytotoxicity of alpha synuclein (αSyn) as well as brain neuropathology. Eventually, I moved to Osaka University, where I continued working on PD and αSyn projects to promote therapeutic research. In this paper, we present the details of these studies in the following order: past, present, and future.