bluuebunny/crossref_metadata_2025_split huggingface dataset:
REVIEWS
Authors: Rowe Nick , Woolfson Wendy , Dempster Paul G. , Kelly Iain , Coad Jane , Hacking Sue 
Published: October 2011

THEATRE IN HEALTH AND CARE, EMMA BRODZINSKI (2010) London: Palgrave Macmillan, 200pp., ISBN: 978-1403997081, Hardback, RRP: £50.00
SCOTTISH INTERNATIONAL SYMPOSIUM FOR STORYTELLING AS A HEALING ART - GLASGOW 2010, 'STORIES FOR HEALTH - WORDS FOR WELLBEING!'
ENSURING SUSTAINABILITY
- ARTS AND HEALTH ACADEMICS IN THE UNITED KINGDOM: A REPORT OF A ONE-DAY WORKSHOP HELD ON 17 MARCH 2011
Contrasts in Alumbramiento
Authors: Michelotti Graciela 
Published: October 2011

Abstract
With contrasting lights and shadows reminiscent of Francisco Zurbarán's paintings, Alumbramiento offers a palette of differing acts: 'to give birth', becoming a parent of your own mother, 'to illuminate' the path to a good death. The initial fear subsides and new alliances are born, inviting the viewer to take a stand.
The Sunday religious revival and a horse named Desire
Authors: Holtmeier Matthew 
Published: October 2011

Abstract
Sunday juxtaposes curiosity, religion and desire amidst the clash of acute sounds vying for attention. These sounds - the banality of knives and forks scraping plates, the instruction of a sermon being delivered via the radio, and a horse's breath and steps - set and break the boundaries between the aforementioned thematics.
Metaphor, hyperbole and simile: A pragmatic approach
Authors: Carston Robyn , Wearing Catherine 
Published: October 2011

AbstractAccording to recent work on lexical pragmatics within the relevance-theoretic framework, grasping the intended meaning of a metaphorically used word requires a process of adjusting the linguistically encoded concept to derive an ad hoc concept whose denotation is broader than that of the lexical concept. Metaphorical uses are claimed to be one kind of loose use of language, on a continuum with approximations, hyperboles and other kinds of meaning extension. The question addressed in this paper is whether this account fully captures the processes involved in understanding metaphors and the kinds of cognitive effects they have. We tackle this question by examining the similarities and differences between metaphors and hyperboles and between metaphors and similes. The upshot of our analyses is two proposals, both requiring further investigation: (a) that a distinction should be drawn between the kind of ad hoc concepts derived for hyperbolic and other loose uses, on the one hand, and metaphorical uses, on the other, and (b) that the understanding of some metaphorical uses, in particular extended and/or novel creative cases, is achieved by a different mode of processing altogether, one which gives much greater weight to the literal meaning.
Verbs in the lexicon: Why is hitting easier than breaking?
Authors: McKoon Gail , Love Jessica 
Published: October 2011

AbstractAdult speakers use verbs in syntactically appropriate ways. For example, they know implicitly thatthe boy hit at the fenceis acceptable butthe boy broke at the fenceis not. We suggest that this knowledge is lexically encoded in semantic decompositions. The decomposition forbreakverbs (e.g.crack, smash) is hypothesized to be more complex than that forhitverbs (e.g.kick, kiss). Specifically, the decomposition of abreakverb denotes that “an entity changes state as the result of some external force” whereas the decomposition for ahitverb denotes only that “an entity potentially comes in contact with another entity.” In this article, verbs of the two types were compared in a lexical decision experiment—Experiment 1—and they were compared in sentence comprehension experiments with transitive sentences (e.g.the car hit the bicycleandthe car broke the bicycle)—Experiments 2 and 3. In Experiment 1, processing times were shorter for thehitthan thebreakverbs and in Experiments 2 and 3, processing times were shorter for thehitsentences than the break sentences, results that are in accord with the complexities of the postulated semantic decompositions.
Irradiation of strontium chloride targets at proton energies above 35 MeV to produce PET radioisotope Y-86
Authors: Medvedev Dmitri G. , Mausner Leonard F. , Srivastava Suresh C. 
Published: October 2011

Abstract
Proton irradiation of natural and enriched SrCl2 targets was used to produce PET radioisotope 86Y. The proton energy was degraded from the incident 117.8 MeV to induce the 88Sr(p,3n) reaction. For the irradiation three pellets made of natSrCl2 (6.61 and 74.49 g) and 88SrCl2 (5.02 g) were pressed and individually encapsulated in stainless steel target bodies. The two smaller targets were irradiated for 0.5–1 h at the energy ∼ 46→37 MeV to take advantage of the peak in the excitation function of the 88Sr(p,3n) reaction. The larger target was irradiated at 66.4→44.6 MeV. The irradiated pellets were chemically processed to selectively separate 86Y radioisotope using Eichrom DGA (N,N,N´,N´-tetra-n-octyldiglycolamide) resin. The production yields of 86Y were determined to be 10–13 mCi/μA h. Coproduction of 87mY in the final product was 34% for natSrCl2 and 54% for 88SrCl2 target. The chemical separation yield of yttrium reached 88–92%. The developed chemical procedure allows for the same day processing and shipment of the isotope to users.
Craniofacial and Dental Features in Kabuki Syndrome Patients
Authors: Sobral Samantha Do Prado , Leite André Ferreira , Figueiredo Paulo Tadeu Sousa , Ferrari Íris , Safatle Heloísa Pires Neto , Córdoba Mara Santos , Versiani Beatriz Ribeiro , Acevedo Ana Carolina , Mestrinho Heliana Dantas 
Published: October 2011

Objective To describe oral manifestations in Brazilian individuals with Kabuki syndrome, a multiple congenital anomaly/mental retardation syndrome. Study Design A total of 16 Kabuki syndrome individuals, aged between 8 to 24 years and of both sexes, were referred by the Department of Clinical Genetics for oral treatment and follow-up to the Oral Care Center for Inherited Diseases, University Hospital of Brasília, Brasília, Brazil. Each individual underwent complete physical examination, as well as intraoral and radiographic examinations. Results Craniofacial and dental alterations were observed in all Kabuki syndrome patients examined. In addition, atypical shape of the molars' crowns, occlusal convergence of the premolars' crowns, and root dilaceration were also observed. Enamel diffuse opacities were observed in permanent dentition (n = 10). Conclusion A great clinical heterogeneity was observed in Kabuki syndrome individuals in line with previous studies in the literature. Further clinical and molecular studies are necessary in order to better understand the presence of dental anomalies in this syndrome.
Team-Oriented Care for Orofacial Clefts: A Review of the Literature
Authors: Mcgrattan Katlyn , Ellis Charles 
Published: October 2011

Objective To examine the process of team-oriented care for children with orofacial clefts. Design Systematic review of available studies reporting team-oriented management of children and adults with orofacial clefts. We identified studies from OVID, PsychINFO, REHABDATA, PubMed, and The Cleft Palate–Craniofacial Journal to complete this review. Main Outcome Measures Process of team-oriented treatment, which included use of team-oriented care, continuity of team-oriented care, and approaches to team-oriented care. Results We identified nine studies including 1398 participants. We found that studies examining team-oriented approaches to orofacial clefts were limited. Studies of orofacial teams suggest that use of team-oriented approaches to care are highly variable. It is unclear how these inconsistencies in approaches to care influence long-term outcomes. Conclusions Although the literature suggests that the process of team-oriented care results in better outcomes in individuals with orofacial clefts, process of care as a measurable outcome has yet to be adequately examined. Future studies are needed to investigate the impact on clinical outcomes and their relationship to cost effectiveness and efficiency of care.
Planning and Execution of the Longest Horizontal Well in ADCO
Authors: Kuyken Chris , Al-Bakr Salem , Abu Aishah Abdel Nasser , El-Hadidy Khaled , El-Reyami Mazin , Gomes Jorge Salgado , James Ron , Hahne Ulrich 
Published: October 2011

Abstract
This paper discusses the planning process, execution and lessons learned of an advanced horizontal water injector in a tight carbonate reservoir, onshore United Arab Emirates. The well design required a 10,000 ft horizontal section, to be geosteered in a 6⅛-in. hole through a narrow TVD window of 5 ft, just above the oil water contact.
The challenges were multiple, not only from the rig capability and BHA design point of view, but also from the geosteering and formation evaluation aspects pertaining to borehole hydraulics, completion and stimulation. For injection monitoring analysis the completion had to be run with a perforated 3 1/2-in. stinger design to deploy a 19,500 ft distributed temperature sensing (DTS) system to TD. Four main justifications to execute this pilot project were identified:
to improve injectivity and therefore the area sweep efficiency in the down flank area of the field to segment the wellbore to provide for future selective stimulation along 10,000 ft of horizontal section to deploy a DTS system to continuously monitor the water injection profile to minimize the number of injection wells in the field, reducing CAPEX, OPEX, surface hook ups and field footprint.
The paper discusses the business case for this project, which includes an initial pilot well containing a 5,100 ft lateral section and four extended reach drilling (ERD) wells, each with a 10,000 ft lateral hole section. Furthermore, best practices from the detailed planning phase to the execution of the first extended reach well are reviewed in this paper.
Strengthening the Kawa Model: Japanese Perspectives on Person, Occupation, and Environment
Authors: Wada Mineko 
Published: October 2011

Background. The Kawa model emerged to meet a need for occupational therapy models and theories relevant to Japanese clients and since its inception has evolved considerably. Purpose. To provide an overview of the Kawa model and to contribute to a critique of the model from Japanese perspectives on person, occupation, and environment. Key Issues. The paper notes that the Kawa model does not portray inner self nor does it integrate one's active belonging; the author identifies the challenges of addressing issues related to occupations, and introduces the concept of seken (day-to-day community). Implications. The model would be strengthened by presenting inner self and a discrete layer of seken in the environment to effectively articulate belonging. The ways of presenting occupation need to be improved to capture relationships between occupation and belonging, effects of occupations, and positive and negative meanings attributed to an occupation. Exploring relationships between self, occupation, life flow, and harmony is warranted.
Subcutaneous Adipose Tissue Macrophage Infiltration Is Associated With Hepatic and Visceral Fat Deposition, Hyperinsulinemia, and Stimulation of NF-κB Stress Pathway
Authors: Lê Kim-Anne , Mahurkar Swapna , Alderete Tanya L. , Hasson Rebecca E. , Adam Tanja C. , Kim Joon Sung , Beale Elizabeth , Xie Chen , Greenberg Andrew S. , Allayee Hooman , Goran Michael I. 
Published: October 2011

OBJECTIVE
To examine in obese young adults the influence of ethnicity and subcutaneous adipose tissue (SAT) inflammation on hepatic fat fraction (HFF), visceral adipose tissue (VAT) deposition, insulin sensitivity (SI), β-cell function, and SAT gene expression.

RESEARCH DESIGN AND METHODS
SAT biopsies were obtained from 36 obese young adults (20 Hispanics, 16 African Americans) to measure crown-like structures (CLS), reflecting SAT inflammation. SAT, VAT, and HFF were measured by magnetic resonance imaging, and SI and β-cell function (disposition index [DI]) were measured by intravenous glucose tolerance test. SAT gene expression was assessed using Illumina microarrays.

RESULTS
Participants with CLS in SAT (n = 16) were similar to those without CLS in terms of ethnicity, sex, and total body fat. Individuals with CLS had greater VAT (3.7 ± 1.3 vs. 2.6 ± 1.6 L; P = 0.04), HFF (9.9 ± 7.3 vs. 5.8 ± 4.4%; P = 0.03), tumor necrosis factor-α (20.8 ± 4.8 vs. 16.2 ± 5.8 pg/mL; P = 0.01), fasting insulin (20.9 ± 10.6 vs. 9.7 ± 6.6 mU/mL; P &lt; 0.001) and glucose (94.4 ± 9.3 vs. 86.8 ± 5.3 mg/dL; P = 0.005), and lower DI (1,559 ± 984 vs. 2,024 ± 829 ×10−4 min−1; P = 0.03). Individuals with CLS in SAT exhibited upregulation of matrix metalloproteinase-9 and monocyte antigen CD14 genes, as well as several other genes belonging to the nuclear factor-κB (NF-κB) stress pathway.

CONCLUSIONS
Adipose tissue inflammation was equally distributed between sexes and ethnicities. It was associated with partitioning of fat toward VAT and the liver and altered β-cell function, independent of total adiposity. Several genes belonging to the NF-κB stress pathway were upregulated, suggesting stimulation of proinflammatory mediators.
Age- and Islet Autoimmunity–Associated Differences in Amino Acid and Lipid Metabolites in Children at Risk for Type 1 Diabetes
Authors: Pflueger Maren , Seppänen-Laakso Tuulikki , Suortti Tapani , Hyötyläinen Tuulia , Achenbach Peter , Bonifacio Ezio , Orešič Matej , Ziegler Anette-G. 
Published: October 2011

OBJECTIVE
Islet autoimmunity precedes type 1 diabetes and often initiates in childhood. Phenotypic variation in islet autoimmunity relative to the age of its development suggests heterogeneous mechanisms of autoimmune activation. To support this notion, we examined whether serum metabolite profiles differ between children with respect to islet autoantibody status and the age of islet autoantibody development.

RESEARCH DESIGN AND METHODS
The study analyzed 29 metabolites of amino acid metabolism and 511 lipids assigned to 12 lipid clusters in children, with a type 1 diabetic parent, who first developed autoantibodies at age 2 years or younger (n = 13), at age 8 years or older (n = 22), or remained autoantibody-negative, and were matched for age, date of birth, and HLA genotypes (n = 35). Ultraperformance liquid chromatography and mass spectroscopy were used to measure metabolites and lipids quantitatively in the first autoantibody-positive and matched autoantibody-negative serum samples and in a second sample after 1 year of follow-up.

RESULTS
Differences in the metabolite profiles were observed relative to age and islet autoantibody status. Independent of age-related differences, autoantibody-positive children had higher levels of odd-chain triglycerides and polyunsaturated fatty acid–containing phospholipids than autoantibody-negative children and independent of age at first autoantibody appearance (P &lt; 0.0001). Consistent with our hypothesis, children who developed autoantibodies by age 2 years had twofold lower concentration of methionine compared with those who developed autoantibodies in late childhood or remained autoantibody-negative (P &lt; 0.0001).

CONCLUSIONS
Distinct metabolic profiles are associated with age and islet autoimmunity. Pathways that use methionine are potentially relevant for developing islet autoantibodies in early infancy.
FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection
Authors: Smyth Deborah J. , Cooper Jason D. , Howson Joanna M.M. , Clarke Pamela , Downes Kate , Mistry Trupti , Stevens Helen , Walker Neil M. , Todd John A. 
Published: October 2011

OBJECTIVE
FUT2 encodes the α(1,2) fucosyltransferase that determines blood group secretor status. Homozygotes (A/A) for the common nonsense mutation rs601338A&gt;G (W143X) are nonsecretors and are unable to express histo-blood group antigens in secretions and on mucosal surfaces. This mutation has been reported to provide resistance to Norovirus and susceptibility to Crohn’s disease, and hence we aimed to determine if it also affects risk of type 1 diabetes.

RESEARCH DESIGN AND METHODS
rs601338A&gt;G was genotyped in 8,344 patients with type 1 diabetes, 10,008 control subjects, and 3,360 type 1 diabetic families. Logistic regression models were used to analyze the case-control collection, and conditional logistic regression was used to analyze the family collection.

RESULTS
The nonsecretor A/A genotype of rs601338A&gt;G was found to confer susceptibility to type 1 diabetes in both the case-control and family collections (odds ratio for AA 1.29 [95% CI 1.20–1.37] and relative risk for AA 1.22 [95% CI = 1.12–1.32]; combined P = 4.3 × 10−18), based on a recessive effects model.

CONCLUSIONS
Our findings linking FUT2 and type 1 diabetes highlight the intriguing relationship between host resistance to infections and susceptibility to autoimmune disease.
Radiographic appearance of the thorax of clinically normal alpaca crias
Authors: Nelson Nathan C. , Mattoon John S. , Anderson David E. 
Published: October 2011

Abstract
Objective—To quantitatively and qualitatively assess the radiographic appearance of the thorax of clinically normal alpaca crias.
Animals—21 clinically normal alpaca crias.
Procedures—Left-right lateral (LR), right-left lateral (RL), dorsoventral (DV), and ventrodorsal (VD) projections of the thorax were acquired. To account for differences in cria size, measurements of thoracic structures were compared with other anatomic landmarks.
Results—Mean ± SD vertebral heart scale was 9.36 ± 0.65 for LR projections, 9.36 ± 0.59 for RL projections, 8.21 ± 0.51 for DV projections, and 8.65 ± 0.57 for VD projections. Dimensions of the heart were compared with the length of the T3 through T5 vertebral bodies, third to fifth rib distance, and thoracic height and width, which provided additional methods of cardiac evaluation. For RL projections, mean ratio of the right cranial pulmonary artery diameter to the third rib width was 0.41 ± 0.10 and mean ratio of the right cranial pulmonary vein to the third rib width was 0.44 ± 0.10. Caudal lobar pulmonary vessels and the caudal vena cava were difficult to quantitatively assess on DV or VD projections. On lateral projections, the trachea was increased in diameter at the origin of the right cranial lobar bronchus. No qualitative differences were found between LR and RL radiographs. The lungs were generally better inflated on VD projections, with more separation of the heart and diaphragm.
Conclusions and Clinical Relevance—Establishment of radiographic values for alpaca crias should prove useful in assessment of thoracic disease in this species.
Effects of in vivo lidocaine administration at the time of ischemia and reperfusion on in vitro contractility of equine jejunal smooth muscle
Authors: Guschlbauer Maria , Feige Karsten , Geburek Florian , Hoppe Susanne , Hopster Klaus , Pröpsting Marcus J. , Huber Korinna 
Published: October 2011

Abstract
Objective—To determine whether administration of lidocaine during ischemia and reperfusion in horses results in concentrations in smooth muscle sufficient to protect against the negative consequences of ischemia-reperfusion injury on smooth muscle motility.
Animals—12 horses.
Procedures—Artificial ischemia and reperfusion injury of jejunal segments was induced in vivo in conjunction with lidocaine treatment during ischemia (IRL) or without lidocaine treatment (IR). Isometric force performance was measured in vitro in IRL and IR smooth muscle preparations with and without additional in vitro application of lidocaine. Lidocaine concentrations in smooth muscle were determined by means of high-performance liquid chromatography. To assess the influence of lidocaine on membrane permeability, activity of creatine kinase and lactate dehydrogenase released by in vitro incubated tissues was determined biochemically.
Results—In vivo administration of lidocaine allowed maintenance of contractile performance after an ischemia and reperfusion injury. Basic contractility and frequency of contractions were significantly increased in IRL smooth muscle tissues in vitro. Additionally, in vitro application of lidocaine achieved further improvement of contractility of IR and IRL preparations. Only in vitro application of lidocaine was able to ameliorate membrane permeability in smooth muscle of IR and IRL preparations. Lidocaine accumulation could be measured in in vivo treated samples and serum.
Conclusions and Clinical Relevance—In vivo lidocaine administration during ischemia and reperfusion had beneficial effects on smooth muscle motility. Initiating lidocaine treatment during surgery to treat colic in horses may improve lidocaine's prokinetic features by protecting smooth muscle from effects of ischemia and reperfusion injury.
Radiographic evaluation of changes in the proximal phalanx of Thoroughbreds in race training
Authors: Beccati Francesca , Pepe Marco , Di Meo Antonio , Davanzo Sveva , Moriconi Franco 
Published: October 2011

Abstract
Objective—To evaluate changes in the cortical bone of the proximal phalanx of the fore-limbs of Thoroughbreds in response to training.
Animals—Twenty-seven 2-year-old Thoroughbreds (20 females, 2 males, and 5 geldings).
Procedures—Horses were principally in training for races in a straight line and in a clockwise direction. Lateromedial and dorsopalmar radiographic views of each metacarpophalangeal joint were obtained before the horses started training and 1 year after starting exercise and racing. Width of the dorsal, palmar, lateral, and medial cortex and the width and thickness of the medulla were measured. Ratios (rather than absolute values) were used to remove the effect of differences in bone size among horses.
Results—10 horses were lost from the study. Radiographs were obtained for 17 horses 1 year after starting training (9 horses raced in a clockwise direction, and 8 raced in clockwise and counterclockwise directions). There was no difference between the cortical bone in the right and left forelimbs at the start of the study. After training for 1 year, the palmar cortex in the right forelimb was significantly thicker than that in the left forelimb.
Conclusions and Clinical Relevance—The strain patterns, biomechanics of rapid exercise, and type of training most probably determined differences in the adaptive responses of the proximal phalanx. The data reported here can be used in the evaluation of weight-bearing distribution along the proximal phalanx and evaluation of the relationship between exercise and bone remodelling of the proximal phalanx.
Nonlinear increase in bubbles radii caused by sound in a bubbly liquid
Authors: Perelomova Anna , Pelc-Garska Weronika 
Published: October 2011

Abstract
The nonlinear interaction of acoustic and entropy modes in a bubbly liquid is considered. The reasons for interaction are both nonlinearity and dispersion. In the field of intense sound, a decrease in the mixture density is predicted. That corresponds to the well-established growth of bubbles volumes due to rectified diffusion. The nonlinear interaction of modes as a reason for a bubble to grow due to sound, is discovered. The example considers variation in the mixture density and bubbles radii caused by acoustic soliton.