bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consistency of retrospective reports of peritraumatic responses and their relation to PTSD diagnostic status
Authors: David Annie‐Claude , Akerib Vivian , Gaston Louise , Brunet Alain 
Published: September 2010

AbstractFew studies have examined whether trauma‐exposed individuals are consistent in their retrospective reports of how they reacted at the time of trauma exposure, and whether this phenomenon has any implications at the diagnostic level. In a series of three longitudinal studies (N = 113) with different timeframes, the authors prospectively investigated the consistency of peritraumatic response scores as a function of posttraumatic stress disorder (PTSD) diagnostic status. Across the three studies, consistency of scores was better among individuals who either did not develop PTSD or who remitted from it than among those whose PTSD did not remit. These results are consistent with the literature suggesting that compromised memory processes are related to sustained PTSD.
A new noninvasive method for determination of laryngeal sensory function
Authors: Bock Jonathan M. , Blumin Joel H. , Toohill Robert J. , Merati Albert L. , Prieto Thomas E. , Jaradeh Safwan S. 
Published: September 2010

AbstractObjectives/Hypothesis:We report a new surface technique for studying sensory conduction in the superior laryngeal nerve (SLN).Study Design:Prospective controlled cohort study at an academic tertiary care hospital.Methods:Surface stimulation of the vagus nerve 7–10 cm proximal to a surface electrode placed over the cricothyroid muscle was performed in controls and in subjects with needle electromyographic‐confirmed laryngeal neuropathy. Cathodal stimulation was applied below the mastoid process behind the sternocleidomastoid muscle. Nerve conduction parameters were determined.Results:Noninvasive SLN evoked potential studies were performed on healthy volunteers (n = 28) as well as neuropathic subjects (n = 27). Compared to controls, the neuropathic subjects had statistically significant differences in baseline‐to‐peak amplitude, conduction velocity, and intrasubject side‐to‐side amplitude ratio (P <.01) of their surface evoked laryngeal sensory action potential (SELSAP).Conclusions:Laryngeal sensory nerve conduction can be determined noninvasively by evaluating SELSAP waveform. This study provides a reproducible method for electrophysiologic evaluation of a sensory branch of the SLN. Laryngoscope, 2011
What treatment for early‐stage glottic carcinoma among adult patients: CO2 endolaryngeal laser excision versus standard fractionated external beam radiation is superior in terms of cost utility?
Authors: Higgins Kevin M. 
Published: September 2010

AbstractObjectives/Hypothesis:To determine which treatment for Tis/T1 glottic carcinoma among adult patients, transoral CO2 laser excision (TOL) versus external beam radiation (XRT), is superior in terms of cost utility.Study Design:Cost‐utility analysis.Methods:Six head‐to‐head comparison studies and 22 consecutive case series were identified to examine oncologic control. The case series were pooled as a composite group. Primary end points were local control (LC), laryngectomy‐free survival (LFS), and overall survival (OS). Objective and subjective voice‐quality measures were secondary end points. Third‐party payer perspective was adopted for cost‐utility analysis. Operational and capital costs were determined with the microcosting method. Rollback calculations and quality adjusted life years (QALYs) were calculated with decision‐tree modeling.Results:There were no significant differences between TOL surgery and XRT with respect to LC (odds ratio [OR], 0.81; 95% confidence interval [CI], 0.51‐1.3) and LFS (OR, 0.84, 95% CI, 0.42‐1.66). The weighted mean difference for OS was 0.03. There were no objective differences for measures of voice quality. Decision‐tree analysis was undertaken using mean 5‐year local control initial probabilities. CO2 laser cost $2475.65/case (US $2407.32/case), generating 1.663 QALYs, whereas radiation cost $4965.85/case (US $4828.79/case), generating 1.506 QALYs. This contrasts initial upstream costs for CO2 laser (∼$1889/case, ∼US $1836.86/case) and radiation (∼$2454.70/case, ∼US $2386.95/case).Conclusions:This meta‐analysis shows that there is no clear difference in oncologic outcome between TOL surgery and XRT. There is a trend for improved post‐treatment voice quality with XRT, although the clinical significance of this is questionable. TOL surgery dominates XRT from a cost‐utility standpoint primarily because of the enhanced downstream affordability of salvage treatment. Laryngoscope, 2011
Enhanced efficiency of polymeric solar cells via alignment of carbon nanotubes
Authors: Radbeh Roshanak , Parbaile Emilien , Chakaroun Mohamad , Ratier Bernard , Aldissi Matt , Moliton André 
Published: September 2010

AbstractCarbon nanotubes (CNTs) are well‐known electron acceptor materials for use in optoelectronic devices due to their appropriate electronic properties. In this work, we report on their use as a part of the multi‐component active layer in organic solar cells to provide better transport of photogenerated charges. To optimize transport, orientation of CNTs perpendicular to the electrodes of solar cells with an active layer of poly(3‐hexylthiophene)–CNT–(6,6‐phenyl C61 butyric acid methyl ester) (P3HT–CNT–PCBM) composite is preferable. In order to achieve this preferred orientation by applying an electric field on the device electrodes, polarization of CNT solutions was studied using dielectric spectroscopy. We find that an improved orientation can be achieved with a high‐frequency AC electric field due to the alternating force exerted rapidly on field‐induced dipoles of the nanotubes. Following these experiments, the orientation method was applied to organic solar cells with a sandwich structure in which the active layer consists of P3HT–CNT–PCBM. The electric field was applied continuously on the electrodes during annealing at a temperature near the glass transition of the polymer matrix. We demonstrate that a significant increase in cell performance (i.e. open‐circuit voltage = 0.61 V, efficiency = 4.53%, fill factor = 0.46) can be achieved, which may signify a better path created by the oriented nanotubes for carrier transport to the electrodes. Copyright © 2010 Society of Chemical Industry
Subcellular fractionation methods and strategies for proteomics
Authors: Lee Yie Hou , Tan Hwee Tong , Chung Maxey C. M. 
Published: September 2010

AbstractDevelopments in subcellular fractionation strategies have provided the means to profile and analyze the protein composition of organelles and cellular structures by proteomics. Here, we review the application of classical (e.g. density gradient centrifugation) and emerging sophisticated techniques (fluorescent‐assisted organelle sorting) in the fractionation, and statistical/bioinformatics tools for the prediction of protein localization in subcellular proteomics. We also review the validation methods currently used (such as microscopy, RNA interference and multiple reaction monitoring) and discuss the importance of verification of the results obtained in subcellular proteomics. Finally, the numerous challenges facing subcellular proteomics including the dynamics of organelles are being examined. However, complementary approaches such as modern statistics, bioinformatics and large‐scale integrative analysis are beginning to emerge as powerful tools to proteomics for analyzing subcellular organelles and structures.
Possibility of non‐adiabatic level crossing by DFT study of tautomerism and potential energy surfaces in of 3‐hydroxy‐5‐(pyrimidin‐2‐yl)‐2H‐pyrrol‐2‐one and its tautomer
Authors: Tavakol Hossein , Sabzyan Hassan 
Published: September 2010

Abstract3‐Hydroxy‐5‐(pyrimidin‐2‐yl)‐2H‐pyrrol‐2‐one (HYPO, T1) and 2‐hydroxy‐5‐(pyrimidine‐2‐yl)‐3H‐pyrrole‐3‐one (HYPO, T2) have designed in this research to study potential energy curves for their dynamic motions and possibility of crossing between levels. Study of tautomerism shows that T1 tautomer is more stable than T2 (about 5.83 kJ/mol). Dynamic study of possible motions show rate constants (highest possible) equal to 8.82 M/s for tautomerism, 1.70 × 109 M/s for relative rotation of ring (rr) and 3.67 × 106 M/s for rotation of OH bond (br). Moreover, variations of orbital populations, NBO charges, hybridations, and acceptor–donor interactions in IRC steps have been investigated to study the possibility of non‐adiabatic crossing between tautomerism and ring rotation potential energy curves. The data showed that in spite of the fact that these two potentials share three common points, these two potential curves cannot have non‐adiabatic crossing because of different symmetries and a large difference between their barrier energies. Copyright © 2010 John Wiley & Sons, Ltd.
Formation of long‐range stripe patterns with sub‐10‐nm half‐pitch from directed self‐assembly of block copolymer
Authors: Takenaka Mikihito , Aburaya Shusuke , Akasaka Satoshi , Hasegawa Hirokazu , Hadjichristidis Nikos , Sakellariou George , Tada Yasuhiko , Yoshida Hiroshi 
Published: September 2010

AbstractWe have demonstrated directed self‐assembly of poly(styrene‐b‐dimethylsiloxiane) (PS‐b‐PDMS) down to sub‐10‐nm half‐pitch by using grating Si substrate coated with PDMS. The strong segregation between PS and PDMS enables us to direct the self‐assembly in wide grooves of the grating substrate up to 500 nm in width. This process can be applied to form various type of sub‐10‐nm stripe pattern along variety of grating shape. © 2010 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2010
Integrated prediction of the effect of mutations on multiple protein characteristics
Authors: Johnston Michael A. , Søndergaard Chresten R. , Nielsen Jens Erik 
Published: September 2010

AbstractSite‐directed mutagenesis is routinely used in modern biology to elucidate the functional or biophysical roles of protein residues, and plays an important role in the field of rational protein design. Over the past decade, a number of computational tools have been developed that can predict the effect of point mutations on a protein's biophysical characteristics. However, these programs usually provide predictions for only a single characteristic. Furthermore, online versions of these tools are often impractical to use for examination of large and diverse sets of mutants. We have created a new web application, (http://enzyme.ucd.ie/PEAT_SA), that can simultaneously predict the effect of mutations on stability, ligand affinity and pK
a values. PEAT‐SA also provides an expanded feature‐set with respect to other online tools which includes the ability to obtain predictions for multiple mutants in one submission. As a result, researchers who use site‐directed mutagenesis can access state‐of‐the‐art protein design methods with a fraction of the effort previously required. The results of benchmarking PEAT‐SA on standard test‐sets demonstrate that its accuracy for all three prediction types compares well to currently available tools. We illustrate PEAT‐SA's potential by using it to investigate the influence of mutations on the activity of Subtilisin BPN′. This example demonstrates how the ability to obtain a wide range of information from one source, that can be combined to obtain deeper insight into the influence of mutations, makes PEAT‐SA a valuable service to both experimental and computational biologists. Proteins 2010. © 2010 Wiley‐Liss, Inc.
Subcontracting work via social networks: migrant Latino Labour and the rebuilding of New Orleans
Authors: Blue Sarah A. , Drever Anita I. 
Published: September 2010

AbstractThe unprecedented destruction caused by Hurricane Katrina attracted tens of thousands of Latino migrants to work in clean‐up and reconstruction jobs in the New Orleans area. This study uses a survey of Latino workers in New Orleans and interviews from various actors involved in the recruitment and hiring of migrant labour – including employers, subcontractors, and the workers themselves – to explore how migrant networks function. In particular, it highlights the key role of migrant entrepreneur subcontractors in drawing new migrants and securing them jobs in unfamiliar destinations. This is of conceptual importance to migration theory because it highlights the need to expand the dominant concept of social networks to include employers, recruiters, and other migrant service‐providers. Latino migration to New Orleans provides insight into the complexity of contemporary network migration, including the overlapping roles of friend, family, and employer. Copyright © 2010 John Wiley & Sons, Ltd.
Comparative studies on transport and magnetotransport behaviour of as‐deposited and ex situ annealed A‐type antiferromagnetic Nd0.45Sr0.55MnO3 films
Authors: Zhang Q. , Zhang Y. Q. , Zhu Y. L. , Cho J. H. , Zhang Z. D. 
Published: September 2010

AbstractMagnetic, transport and magnetotransport properties of A‐type antiferromagnetic Nd0.45Sr0.55MnO3 films with different thicknesses grown on SrTiO3 (100) have been investigated before and after ex situ annealing processes. In contrast to the bulk system, all as‐deposited films exhibit insulating behaviour due to the local Jahn–Teller distortion induced by in‐plane tensile strain. The annealing process only induces an insulator–metal transition in ultrathin film with a thickness of 16 nm, resulting in metallically conductive behaviour and the transport properties similar to those of the bulk. This may be ascribed to the cooperative influences of changes in oxygen content and strain‐induced ${\rm d}_{x^{2} {-} y^{2} } $‐type orbital order owing to the annealing process. When a magnetic field of 70 kOe is applied, the metallic behaviour appears in a broad temperature range in the annealed film with 16 nm thickness and, the metallic behaviour is also observed in the annealed film with 32 nm thickness. The different effects of the external magnetic field on the transport properties of as‐deposited and annealed Nd0.45Sr0.55MnO3 films are discussed.
A systematic study of optical and Raman spectra of peapod‐based DWNTs
Authors: Botka Bea , Pekker Áron , Botos Ákos , Kamarás Katalin , Hackl Rudi 
Published: September 2010

AbstractWe followed the preparation of double‐walled carbon nanotubes (DWNTs) from fullerene peapods by optical and Raman spectroscopy in a systematic way. 1.4 nm average diameter nanotubes were opened by oxidation in air, and filled with C60 by sublimation. The peapods were converted to DWNTs by annealing at 1250 °C. As a reference, a control sample was also prepared, where the same sequence of treatments was applied but no C60 was added. We monitored each preparation step from pristine nanotubes to DWNTs by Raman and wide range FIR‐UV transmission spectroscopy. Both free carrier absorption and interband transitions decrease in intensity in DWNTs, indicating that there cannot be significant charge transfer between the outer and the inner tube. Fullerene features show up in the peapod optical spectra, but the transitions of inner tubes are not observed in the DWNT spectra. In the Raman spectra of peapods, the radial breathing modes (RBMs) of the nanotubes show clear changes. Beside the shifts that were reported earlier, the linewidths of the components become smaller. The RBMs of the outer tubes are shifted back to their original position when the peapods are converted to DWNTs.
Investigation of hydrogenated HiPCo nanotubes by infrared spectroscopy
Authors: Németh Katalin , Pekker Áron , Borondics Ferenc , Jakab Emma , Nemes Norbert M. , Kamarás Katalin , Pekker Sándor 
Published: September 2010

AbstractTwo different reductive synthetic methods were applied to hydrogenate the sidewalls of HiPCo single‐walled carbon nanotubes (SWNTs). In the first one, the reductive agent was melted potassium which doped and exfoliated the nanotube bundles, so that before hydrogenation all of the tubes had been converted to metallic ones. In the second method, doping occurred just before hydrogenation by naphthalenide radical anions. The products were characterized by wide range infrared (30–52 000 cm−1) spectroscopy with special emphasis on the selectivity of the two methods. We found that in the first case the controlling factor is the bandgap, and in the second case the diameter. This difference suggests the importance of the π–π interaction between naphthalenide and the nanotube surface.
Electrocorrosion properties of multiwall carbon nanotubes
Authors: Cherstiouk O. V. , Kuznetsov V. L. , Simonov A. N. , Mazov I. N. , Elumeeva K. V. , Moseva N. S. 
Published: September 2010

AbstractThe electrochemical corrosion properties of a set of multiwalled carbon nanotubes (MWCNT) with different average diameters (〈d〉 = 7–22 nm) and conventional carbon black Vulcan XC‐72 were studied potentiostatically in 2 M H2SO4 at 80 °C. Effects of grinding and high‐temperature treatment (2800 °C) in inert gas on the corrosion stability of MWCNT were also examined. Excitation of MWCNTs with large 〈d〉 in activator mill results in local disruption of the fine structure of the NTs and increase of the corrosion current densities. No rupture and changes of the corrosion behaviour occur for MWCNTs with lower 〈d〉 after grinding. High‐temperature treatment of MWCNTs leads to removal of amorphous carbon and defects from the surface of the materials and results in drastic decrease of the reactivity of the surface of the materials towards electrocorrosion. The ABET‐weighted corrosion current densities of the MWCNTs are significantly lower than that of conventional XC‐72 material evidencing of their higher stability towards electrocorrosion.
Two New Xanthones from Hypericum sampsonii and biological activity of the isolated compounds
Authors: Xin Wen‐Bo , Mao Zhu‐Jun , Jin Gui‐Lin , Qin Lu‐Ping 
Published: September 2010

AbstractPhytochemical investigation of the CH2Cl2 extract of the aerial part of Hypericum sampsonii yielded two new prenylated xanthones, hypericumxanthone A and B, together with three known xanthones. Their structures were elucidated by analysis of physical and spectral (UV, IR, mass and NMR) data and comparison of spectroscopic data with those reported previously. All these compounds were evaluated for in vitro antibacterial activity against methicillin‐resistant Staphylococcus aureus (MRSA). Two new compounds were also tested for their cytotoxicity against human breast (MCF‐7), hepatoma (HepG2), colon (HT‐29) and lung (A549) tumour cell lines. Two new compounds showed moderate antibacterial activities at minimum inhibitory concentrations (MIC) of 16 and 32 µg/mL, respectively, whereas the positive standard antibacterial drug, vancomycin, showed an MIC of 8 µg/mL. The other compounds were inactive against MRSA. In addition, hypericumxanthone B showed weak inhibitory activities against four human tumour cell lines. Copyright © 2010 John Wiley & Sons, Ltd.
Oral administration of Aloe vera and honey reduces walker tumour growth by decreasing cell proliferation and increasing apoptosis in tumour tissue
Authors: Tomasin Rebeka , Cintra Gomes‐Marcondes Maria Cristina 
Published: September 2010

AbstractCancer is diagnosed in approximately 11 million people and is responsible for almost 8 million deaths worldwide every year. Research in cancer control has shown the importance of co‐adjuvant therapies. Aloe vera may reduce tumour mass and metastasis rates, while honey may inhibit tumour growth. This study verified the influence of Aloe vera and honey on tumour growth and in the apoptosis process by assessing tumour size, the cell proliferation rate (Ki67‐LI) and Bax/Bcl‐2 expression at 7, 14 and 20 days after Walker 256 carcinoma implant in Wistar rats distributed into two groups: the WA group – tumour‐bearing rats that received a gavage with a 670 µL/kg dose of Aloe vera and honey solution daily, and the CW group – tumour‐bearing rats which received only a 0.9% NaCl solution. The effect of Aloe vera and honey against tumour growth was observed through a decrease in relative weight (%) and Ki67‐LI in tumours from the WA group compared with those from the CW group. The Bax/Bcl‐2 ratio increased in tumours from the WA group at all tested timepoints. These data suggest Aloe vera and honey can modulate tumour growth by reducing cell proliferation and increasing apoptosis susceptibility. Copyright © 2010 John Wiley & Sons, Ltd.
Product defect rate confidence bound with attribute and variable data
Authors: Kang Lulu , Brenneman William A. 
Published: September 2010

AbstractThe upper confidence bound for a product defect rate is a very important index for evaluating the production process in industry. In this paper, we provide a bootstrap methodology to construct a (1−α)100% upper confidence bound for the overall defect rate of a product whose quality assessment involves multiple pass/fail binary data and multiple continuous data. When only the pass/fail data are included we propose using a bootstrap method which is consistent with the Clopper–Pearson one‐sided confidence interval. When only the continuous data are included the BCa bootstrap method is recommended. These two methods are combined to provide an upper confidence bound for the overall defect rate of the product when multiple pass/fail binary data and multiple continuous data are present. All methods are clearly stated in algorithmic form, investigated through simulation and demonstrated using example data sets. In the simulation studies and examples the proposed algorithms show great advantages in both coverage probability and computational efficiency. Copyright © 2010 John Wiley & Sons, Ltd.
Autoxidation of cyclohexene catalysed by a rhodium complex
Authors: van Vugt Barry H. , Drenth W. 
Published: September 2010

AbstractRhCl(PPh3)3 is used in the catalytic reaction between cyclohexene and oxygen in benzene at 30°. 2‐Cyclohexen‐1‐yl hydroperoxide is formed almost quantitatively. The reaction has an induction period during which the phosphine of the rapidly formed RhCl(PPh3)2.O2 is oxidized. The induction period is eliminated by addition of peroxide, which oxidizes the phosphine rapidly. Added Ph3P and phenols have inhibiting properties; they irreversibly change and deactivate the catalyst. Part of the rhodium is present in an esr‐active form, RhII.O−2. The reaction is zero order in O2 and of the order 1.42 in cyclohexene, while the order in Rh varies between 0.50 and 0.64.All these observations as well as literature data are critically evaluated. They do not permit of a decision being made between a radical chain and a coordination‐sphere mechanism. Thus, the rather general belief that this reaction follows a radical chain path is not based on solid reasoning.
Photoreactions of aromatic compounds. XXXVI, Nucleophilic photosubstitution reactions of some derivatives of imidazole and pyrazole
Authors: Oldenhof C. , Cornelisse J. 
Published: September 2010

AbstractNucleophilic photosubstitution of nitro derivatives of 1‐methylimidazole and 1‐methylpyrazole strongly depends on the position of the nitro group. In the imidazole series the 5‐nitro compound is the most reactive isomer: photochemical replacement of the nitro group by cyano or methoxy proceeds in good yield, thus providing useful methods for the preparation of 5‐cyano‐ and 5‐methoxy‐1‐methylimidazole. Of the nitro‐substituted 1‐methylpyrazoles, the 3‐nitro derivative is the most reactive isomer: photocyanation yields equal amounts of 1‐methyl‐3‐nitro:4‐cyanopyrazole and 1 ‐methyl‐3‐nitrosopyrazole. Some of the reactions proceed by normal bimolecular aromatic photo‐substitution; others bear resemblance to the photoreactions of methoxy‐benzenes and ‐naphthalenes in which a cation radical is intermediate. Anodic cyanation of some derivatives of imidazole and pyrazole is also investigated.