bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody‐secreting cells
Authors: Ichikawa H. Travis , Conley Thomas , Muchamuel Tony , Jiang Jing , Lee Susan , Owen Teresa , Barnard Jennifer , Nevarez Sarah , Goldman Bruce I. , Kirk Christopher J. , Looney R. John , Anolik Jennifer H. 
Published: September 2011

AbstractObjectiveTo investigate the hypothesis that proteasome inhibition may have potential in the treatment of SLE, by targeting plasmacytoid dendritic cells (PDCs) and plasma cells, both of which are critical in disease pathogenesis.MethodsLupus‐prone mice were treated with the nonselective proteasome inhibitors carfilzomib and bortezomib, the immunoproteasome inhibitor ONX 0914, or vehicle control. Tissue was harvested and analyzed by flow cytometry using standard markers. Nephritis was monitored by evaluation for proteinuria and by histologic analysis of kidneys. Serum anti–double‐stranded DNA (anti‐dsDNA) levels were measured by enzyme‐linked immunosorbent assay (ELISA), and total IgG and dsDNA antibody‐secreting cells (ASCs) by enzyme‐linked immunospot assay. Human peripheral blood mononuclear cells or mouse bone marrow cells were incubated with Toll‐like receptor (TLR) agonists and proteasome inhibitors, and interferon‐α (IFNα) levels were measured by ELISA and flow cytometry.ResultsEarly treatment of lupus‐prone mice with the dual‐targeting proteasome inhibitors carfilzomib or bortezomib or the immunoproteasome‐specific inhibitor ONX 0914 prevented disease progression, and treatment of mice with established disease dramatically abrogated nephritis. Treatment had profound effects on plasma cells, with greater reductions in autoreactive than in total IgG ASCs, an effect that became more pronounced with prolonged treatment and was reflected in decreasing serum autoantibody levels. Notably, proteasome inhibition efficiently suppressed production of IFNα by TLR‐activated PDCs in vitro and in vivo, an effect mediated by inhibition of both PDC survival and PDC function.ConclusionInhibition of the immunoproteasome is equally efficacious as dual targeting agents in preventing lupus disease progression by targeting 2 critical pathways in disease pathogenesis, type I IFN activation and autoantibody production by plasma cells.
Scaled‐up separation of cellobiohydrolase1 from a cellulase mixture by ion‐exchange chromatography
Authors: Ye Zhuoliang , Lane Andrew N. , Willing Gerold A. , Berson R. Eric 
Published: September 2011

AbstractEnzymatic hydrolysis of cellulose often involves cellulases produced by Trichoderma reesei, of which cellobiohydrolase1 (CBH1) is the most abundant (about 60% of total cellulases) and plays an important role in the hydrolysis of crystalline cellulose. A method for separating sufficient quantities from the bulk cellulase cocktail is highly desirable for many studies, such as those that aim to characterize binding and hydrolysis kinetics of CBH1. In this work, CBH1 was separated from other Spezyme CP cellulases by ion‐exchange chromatography using an efficient modification of a smaller scale process. The ion‐exchange column was connected to a vacuum manifold system to provide a steady flow through parallel columns and thus achieve scale‐up for enzyme separation. With five 5‐mL columns running in parallel, about 55 mg of CBH1 was separated from 145 mg of Spezyme CP in a single separation. Step elution was used to replace the continuous gradient used at smaller scale. The purified CBH1 was collected in the fraction eluted with a buffer containing 0.33 M salt and showed comparable purity and activity as the enzyme purified by a fast protein liquid chromatography system. The stability of separated CBH1 was studied for up to 2 days and good thermal stability was observed. Separated CBH1 also showed both high adsorption to bacterial microcrystalline cellulose with ∼4 μmol/g maximum adsorption and a Ka of 5.55 ± 2.34 μM−1, and good hydrolytic activity based on atomic force microscopy observations that show a reduction in fiber height. © 2011 American Institute of Chemical Engineers Biotechnol. Prog., 2011
Recovery of Terephthalic Acid from Alkali Reduction Wastewater by Cooling Crystallization
Authors: Wu S.‐C. , Cheng Z.‐M. , Wang S.‐D. , Shan X.‐L. 
Published: September 2011

AbstractA process for the recovery and purification of terephthalic acid (TA) from alkali reduction wastewater is reported. TA was first precipitated from alkali reduction wastewater by acidification with sulfuric acid, and then the produced crude TA was dissolved in dimethylacetamide (DMA) so that crude TA could be purified from the solution by cooling crystallization. The results indicated that acidification could reduce the chemical oxygen demand of the wastewater by 83 %, and the purity of TA by crystallization could reach 99.91 %. A correlation was proposed in describing the solubility of crude TA in DMA from 303.4 to 358.65 K, which gives a mean relative discrepancy of less than 1.14 %. The cooling rate of the mother liquor had a large influence on the crystal size distribution. At an average cooling rate of 1.18 K min–1, the particle size distribution of TA was narrow and the average size was about 100 μm. In a bench‐scale study, it was demonstrated that the crystallized product can be recycled as the raw material for polyethylene terephthalate production.
Biomimetic Oxidation Reactions of a Naked Manganese(V)–Oxo Porphyrin Complex
Authors: Lanucara Francesco , Crestoni Maria Elisa 
Published: September 2011

AbstractThe intrinsic reactivity of a manganese(V)‐oxo porphyrin complex, a typically fleeting intermediate in catalytic oxidation reactions in solution, has been elucidated in a study focused on its gas‐phase ion‐chemistry. The naked high‐valent MnV‐oxo porphyrin intermediate 1 ([(tpfpp)MnVO]+; tpfpp=meso‐tetrakis(pentafluorophenyl)porphinato dianion), has been obtained by controlled treatment of [(tpfpp)MnIII]Cl (2‐Cl) with iodosylbenzene in methanol, delivered in the gas phase by electrospray ionization and assayed by FT‐ICR mass spectrometry. A direct kinetic study of the reaction with selected substrates, each containing a heteroatom X (X=S, N, P) including amines, sulfides, and phosphites, was thus performed. Ionic products arising from electron transfer (ET), hydride transfer (HT), oxygen‐atom transfer (OAT), and formal addition (Add) may be observed, with a predominance of two‐electron processes, whereas the product of hydrogen‐atom transfer (HAT), [(tpfpp)MnIVOH]+, is never detected. A thermochemical threshold for the formation of the product radical cation allows an evaluation of the electron‐transfer ability of a MnV‐oxo complex, yielding a lower limit of 7.85 eV for the ionization energy of gaseous [(tpfpp)MnIVO]. Linear free‐energy analyses of the reactions of para‐substituted N,N‐dimethylanilines and thioanisoles indicate that a considerable amount of positive charge is developed on the heteroatom in the oxidation transition state. Substrates endowed with different heteroatoms, but similar ionization energy display a comparable reaction efficiency, consistent with a mechanism initiated by ET. For the first time, the kinetic acidity of putative hydroxo intermediates playing a role in catalytic oxidations, [(tpfpp)FeIVOH]+ and [(tpfpp)MnIVOH]+, has been investigated with selected reference bases, revealing a comparatively higher basicity for the ferryl, [(tpfpp)FeIVO], with respect to the manganyl, [(tpfpp)MnIVO], unit. Finally, the neat association reaction of 2 has been studied with various ligands showing that harder ligands are more strongly bound.
ChemInform Abstract: Solving the Structure of Li Ion Battery Materials with Precession Electron Diffraction: Application to Li2CoPO4F.
Authors: Hadermann Joke , Abakumov Artem M. , Turner Stuart , Hafideddine Zainab , Khasanova Nellie R. , Antipov Evgeny V. , Van Tendeloo Gustaaf 
Published: September 2011

AbstractThe crystal structure of Li2CoPO4F is completely solved from precession electron diffraction data, including the location of the Li atoms.
ChemInform Abstract: Perovskite, LiNbO3, Corundum, and Hexagonal Polymorphs of (In1‐xMx)MO3.
Authors: Belik Alexei A. , Furubayashi Takao , Yusa Hitoshi , Takayama‐Muromachi Eiji 
Published: September 2011

AbstractThe LiNbO3 phase (LN‐phase) of the title compound with x = 0.143 and M: Fe0.5Mn0.5 is synthesized from stoichiometric mixtures of In2O3, Mn2O3, and Fe2O3 (Pt capsule, 6 GPa, 1773 K, 30 min).
ChemInform Abstract: Giant Negative Thermal Expansion in the Iron Perovskite SrCu3Fe4O12.
Authors: Yamada Ikuya , et al. et al. 
Published: September 2011

AbstractPolycrystalline SrCu3Fe4O12 is synthesized from a stoichiometric mixture of Sr(NO3)2, Cu(NO3)2, Fe(NO3)3, and a fivefold molar excess of citric acid dissolved in a mixture of water and ethanediol (433 K, ≈12 h) followed by decomposition of the resulting solid at 723 and 973 K.
ChemInform Abstract: Synthesis and Enhanced Luminescence Properties of Li‐Doped CaTiO3:Pr3+ Ceramic Phosphors.
Authors: Yang Hyun Kyoung , Chung Jong Won , Moon Byung Kee , Choi Byung Chun , Jeong Jung Hyun , Bae Jong Seong , Kim Kwang Ho 
Published: September 2011

AbstractThe title phosphors are prepared by solid state reaction of CaCO3, TiO2, Li2CO3 (0.5, 1, 2, 5 wt.%), and Pr6O11 (800 °C, 4 h, followed by sintering at 1200 °C for 2 h).
ChemInform Abstract: Oxygen‐Deficient R2MoO6‐δ (R: Tb, Dy, Y, Ho, Er, Tm, Yb) with Fluorite Structure as Potential Anodes in Solid Oxide Fuel Cells.
Authors: Aguadero A. , Martinez‐Lope M. J. , Pomjakushin V. , Alonso J. A. 
Published: September 2011

AbstractThe title compounds are synthesized by solid state reaction of stoichiometric mixtures of Ln2O3 (Ln: Y, Dy, Ho, Er, Tm, Yb) and MoO3 (air, 1150 °C, 12 h) followed by treatment in 5% H2/N2 (900 °C, 12 h).
ChemInform Abstract: Ion‐Induced Transformation of Magnetism in a Bimetallic CuFe Prussian Blue Analogue.
Authors: Okubo Masashi , et al. et al. 
Published: September 2011

AbstractK0.14Cu1.43[Fe(CN)6]·5H2O is synthesized by dropwise addition of an aqueous solution of CuSO4 to an aqueous solution of K3[Fe(CN)6].
ChemInform Abstract: Reversible Sodium Ion Insertion in Single Crystalline Manganese Oxide Nanowires with Long Cycle Life.
Authors: Cao Yuliang , Xiao Lifen , Wang Wei , Choi Daiwon , Nie Zimin , Yu Jianguo , Saraf Laxmikant V. , Yang Zhenguo , Liu Jun 
Published: September 2011

AbstractSingle crystalline Na4Mn9O18 nanowires are synthesized using a polymer‐pyrolysis method.
ChemInform Abstract: 3‐V Full Cell Performance of Anode Framework TiNb2O7/Spinel LiNi0.5Mn1.5O4.
Authors: Han Jian‐Tao , Goodenough John B. 
Published: September 2011

AbstractA carbon‐coated TiNb2O7 anode and a LiNi0.5Mn1.5O4 cathode are assembled into 3‐V full cell.
ChemInform Abstract: Room Temperature Synthesis of Protonated Layered Titanate Sheets Using Peroxo Titanium Carbonate Complex Solution.
Authors: Sutradhar Narottam , Sinhamahapatra Apurba , Pahari Sandip Kumar , Bajaj Hari C. , Panda Asit Baran 
Published: September 2011

AbstractA titanium peroxo carbonate complex is prepared from an EtOH solution of Ti(OiPr)4 by precipitation of titanium hydroxide with an ammoniacal H2O solution followed by addition of aqueous (NH4)2CO3 and 30% aq.
ChemInform Abstract: Two Organic Hybrid Thiogermanates [Ni(dien)2](H2dien)Ge2Se6 and [Ni(teta)2]2Ge4S10.
Authors: Liu Xing , Zhou Jian , He Jun , Huang Zhi‐wei 
Published: September 2011

AbstractCompound (III) crystallizes in the triclinic space group P$\bar 1$ with Z = 1 and consists of discrete [Ge2S6]4‐ anions with [Ni(dien)2]2+ and [H2dien]2+ cations as counterions.
ChemInform Abstract: A Metastable Metal with Decagonal Local Symmetry Obtained by Low‐Temperature Pseudomorphosis.
Authors: Kaiser Martin , Isaeva Anna , Ruck Michael 
Published: September 2011

AbstractBlack crystals of the metastable intermetallic compound Bi28Ni25 are prepared by reduction of Bi28Ni25I5 crystals with a solution of BuLi in boiling hexane (69 °C, argon atmosphere, 2 d; 90% yield).
ChemInform Abstract: Generation and Reactivity of Aza‐Oxyallyl Cationic Intermediates: Aza‐[4 + 3] Cycloaddition Reactions for Heterocycle Synthesis.
Authors: Jeffrey Christopher S. , Barnes Korry L. , Eickhoff John A. , Carson Christopher R. 
Published: September 2011

AbstractComputational and experimental data support that the title reaction proceeds through an aza‐oxyallylic cationic intermediate which is stabilized by the N‐alkoxy substituent.
ChemInform Abstract: Mild and Selective Boronic Acid Catalyzed 1,3‐Transposition of Allylic Alcohols and Meyer—Schuster Rearrangement of Propargylic Alcohols.
Authors: Zheng Hongchao , Lejkowski Michal , Hall Dennis G. 
Published: September 2011

AbstractHighly electron‐deficient polyfluoroarylboronic acid catalysts (I)—(IV) are applied to the rearrangement of allylic alcohols and propargylic alcohols.
ChemInform Abstract: FeCl3‐Mediated Reaction of Alkynols with Iodine: An Efficient and Convenient Synthetic Route to Vinyl Iodides.
Authors: Su Lei , Lei Chun‐Yan , Fan Wei‐Yong , Liu Liang‐Xian 
Published: September 2011

AbstractThe FeCl3‐mediated reaction of alkynols with iodine results in the formation of a variety of iodocycloenol ethers.
ChemInform Abstract: Pd‐Catalyzed Intermolecular C—H Amination with Alkylamines.
Authors: Yoo Eun Jeong , Ma Sandy , Mei Tian‐Sheng , Chan Kelvin S. L. , Yu Jin‐Quan 
Published: September 2011

AbstractA novel protocol to effect monoselective C—H amination on a broad range of benzamide substrates with electrophilic O‐benzoyl hydroxylamines is described.
ChemInform Abstract: In situ Generated (Hypo)Iodite Catalysts for the Direct α‐Oxyacylation of Carbonyl Compounds with Carboxylic Acids.
Authors: Uyanik Muhammet , Suzuki Daisuke , Yasui Takeshi , Ishihara Kazuaki 
Published: September 2011

AbstractThe introduction of an O‐acyl group at the α‐position of carbonyl compounds is smoothly achieved using tetrabutylammonium iodide catalyst in the presence of hydrogen peroxide or tert‐butyl hydroperoxide.
ChemInform Abstract: Novel Protection—Deprotection Strategies in Diazeniumdiolate Chemistry: Synthesis of V‐IPA/NO.
Authors: Nandurdikar Rahul S. , Keefer Larry K. , Saavedra Joseph E. 
Published: September 2011

AbstractA five‐step synthesis of potentially liver selective HNO donor V‐IPA/NO (VIII) is elaborated using a protection—deprotection strategy.
ChemInform Abstract: Pd‐Catalyzed [2 + 2 + 1] Coupling of Alkynes and Arenes: Phenol Diazonium Salts as Mechanistic Trapdoors.
Authors: Schmidt Bernd , Berger Rene , Kelling Alexandra , Schilde Uwe 
Published: September 2011

AbstractA wide range of spirocyclic compounds is synthesized by the present new palladium‐catalyzed coupling reaction of internal alkynes with 4‐phenol diazonium salts.
ChemInform Abstract: Iron‐Catalyzed Stereospecific Activation of Olefinic C—H Bonds with Grignard Reagent for Synthesis of Substituted Olefins.
Authors: Ilies Laurean , Asako Sobi , Nakamura Eiichi 
Published: September 2011

AbstractThe iron‐catalyzed functionalization of acyclic or cyclic olefins which possess a directing group such as pyridine via stereospecific C—H bond activation in the presence of a mild oxidant and an aromatic cosolvent takes place in a (Z)‐specific manner.
ChemInform Abstract: Cooperative Transition‐Metal and Chiral Broensted Acid Catalysis: Enantioselective Hydrogenation of Imines to Form Amines.
Authors: Zhou Shaolin , Fleischer Steffen , Junge Kathrin , Beller Matthias 
Published: September 2011

AbstractThe procedure constitutes an attractive and environmentally favorable alternative to reactions with precious‐metal catalysts.
ChemInform Abstract: Asymmetric Aza‐Henry Reaction of Chiral Fluoroalkyl α,β‐Unsaturated N‐tert‐Butanesulfinyl Ketoimines: An Efficient Approach to Enantiopure Fluoroalkylated α,β‐Diamines and α,β‐Diamino Acids.
Authors: Zhang Fan , Liu Zhen‐Jiang , Liu Jin‐Tao 
Published: September 2011

AbstractThe presence of a fluoroalkyl group is crucial for the successful stereoselective aza‐Henry reaction.
ChemInform Abstract: Tandem Catalysis by Lipase in a Vinyl Acetate Mediated Cross‐Aldol Reaction.
Authors: Kumar Manjeet , Shah Bahwal A. , Taneja Subhash C. 
Published: September 2011

AbstractNovozym435/NEt3‐catalyzed treatment of isopropenyl acetate with aromatic aldehydes is found to allow new, mild, and efficient access to β‐hydroxy ketones.
ChemInform Abstract: Grignard‐Type Arylation of Aldehydes via a Rhodium‐Catalyzed C—H Activation under Mild Conditions.
Authors: Yang Luo , Correia Camille A. , Li Chao‐Jun 
Published: September 2011

AbstractThe title reaction provides a new and efficient method to prepare a wide range of benzyl and diarylmethyl alcohols.
ChemInform Abstract: Polystyrene‐Supported Enantiopure 1,2‐Diamines: Development of a Most Practical Catalyst for the Asymmetric Transfer Hydrogenation of Ketones.
Authors: Marcos Rocio , Jimeno Ciril , Pericas Miquel A. 
Published: September 2011

AbstractThe Rh complex RCPC is highly efficient for the hydrogenation of alkyl aryl ketones.
ChemInform Abstract: Catalytic Syntheses of γ‐Functionalized α‐Keto Esters from Thioacetals and N,O‐Acetals.
Authors: Krebs Anke , Bolm Carsten 
Published: September 2011

AbstractEster (I) reacts with aromatic thioacetals (II) under mild conditions providing the α‐keto‐γ‐thio esters (III).
ChemInform Abstract: Phosphorofluoridic Acid Ammonium Salts and Acids: Synthesis, NMR Properties, and Application as Acid Catalysts.
Authors: Murai Toshiaki , Tonomura Yusuke , Takenaka Toru 
Published: September 2011

AbstractHighest yields in the synthesis of the compound (III) are achieved by using the shown catalyst.
ChemInform Abstract: Thiourea Dioxide (TUD): A Robust Organocatalyst for Oxidation of Sulfides to Sulfoxides with TBHP under Mild Reaction Conditions.
Authors: Kumar Subodh , Verma Sanny , Jain Suman L. , Sain Bir 
Published: September 2011

AbstractThe process is highly effective for aromatic and aliphatic thioethers and chemoselective in the presence of other functional groups.
ChemInform Abstract: Synthesis of Unsymmetrical Diarylureas via Pd‐Catalyzed C—N Cross‐Coupling Reactions.
Authors: Breitler Simon , Oldenhuis Nathan J. , Fors Brett P. , Buchwald Stephen L. 
Published: September 2011

AbstractThe Pd‐catalyzed reaction of benzylurea with various aryl chlorides, followed by the hydrogenolysis leads to monoarylurea derivatives.
ChemInform Abstract: Iron‐Catalyzed Quick Homocoupling Reaction of Aryl or Alkynyl Grignard Reagents Using a Phosphonium Ionic Liquid Solvent System.
Authors: Kude Keisuke , Hayase Shuichi , Kawatsura Motoi , Itoh Toshiyuki 
Published: September 2011

AbstractBulky substituents decrease the yield in the presented reaction.
ChemInform Abstract: Synthesis of New Chiral Schiff Bases Containing Bromo‐ and Iodo‐Functionalized Hydroxynaphthalene Frameworks.
Authors: Wang Ying , Wang Mei , Wang Yu , Chen Yuee , Sun Licheng 
Published: September 2011

AbstractHalogen derivatives are converted into their corresponding Schiff bases by means of method D as shown for the examples (III), (VIII) and (X).
ChemInform Abstract: Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds.
Authors: Rudolph Alena , Bos Pieter H. , Meetsma Auke , Minnaard Adriaan J. , Feringa Ben L. 
Published: September 2011

AbstractThe convenient one‐pot procedure includes conjugate addition of alkylmagnesium bromides to α,β‐unsaturated esters and subsequent oxidative cyclization.
ChemInform Abstract: Highly Active and Diastereoselective N,O‐ and N,N‐Yttrium Complexes for Intramolecular Hydroamination.
Authors: Lauterwasser Frank , Hayes Paul G. , Piers Warren E. , Schafer Laurel L. , Braese Stefan 
Published: September 2011

AbstractComplexes (I) and (II) are highly efficient for the reaction of primary aminoalkynes and aminoalkenes giving pyrrolidine and piperidine derivatives.
ChemInform Abstract: Radical Carbonylation of ω‐Alkynylamines Leading to α‐Methylene Lactams. Synthetic Scope and the Mechanistic Insights.
Authors: Ryu Ilhyong , Fukuyama Takahide , Tojino Mami , Uenoyama Yoshitaka , Yonamine Yuka , Terasoma Nozomi , Matsubara Hiroshi 
Published: September 2011

AbstractThe title reaction allows effective access to 5‐ to 8‐membered rings.
ChemInform Abstract: Synthesis and Antitumor Activity of 5‐[1‐(3‐(Dimethylamino)propyl)‐5‐halogenated‐2‐oxoindolin‐ (3Z)‐ylidenemethyl]‐2,4‐dimethyl‐1H‐pyrrole‐3‐carboxamides.
Authors: Lv Kai , Wang Li‐Li , Liu Ming‐Liang , Zhou Xin‐Bo , Fan Shi‐Yong , Liu Hong‐Ying , Zheng Zhi‐Bing , Li Song 
Published: September 2011

AbstractDesign and synthesis of a variety of title compounds (VII) are described.
ChemInform Abstract: A Novel Acid‐Catalyzed C5‐Alkylation of Oxindoles Using Alcohols.
Authors: Reddy Chada Raji , Jithender Enukonda , Krishna Gaddam , Reddy Gunreddy Venkat , Jagadeesh Bharatam 
Published: September 2011

AbstractA wide range of 5‐substituted oxindoles is available.
ChemInform Abstract: Synthesis and Crystal Structure of (4bRS,9bRS)‐5‐ (2,4‐Dimethoxyphenyl) ‐4b,9b‐7,7‐dimethyldihydroxy‐4b,5,6,7,8,9b‐hexahydroindeno [1,2‐b]indole‐9,10‐dione.
Authors: Lobo Gricela , Zuleta Elimar , Charris Katiuska , Capparelli Mario V. , Briceno Alexander , Angel Jorge , Charris Jaime 
Published: September 2011

AbstractThe title compound (III) exhibits only marginal antitumor and antibacterial activities.
ChemInform Abstract: The Davis—Beirut Reaction: N1,N2‐Disubstituted‐1H‐indazolones via 1,6‐Electrophilic Addition to 3‐alkoxy‐2H‐indazoles.
Authors: Conrad Wayne E. , Fukazawa Ryo , Haddadin Makhluf J. , Kurth Mark J. 
Published: September 2011

AbstractA variety of indazole substrates undergoes electrophilic reactions leading to the small libraries of N,N′‐disubstituted indazolones.
ChemInform Abstract: Synthesis and Characterization of Some Novel Isoxazolines and Pyrazolines as Potent Antimicrobial Agents.
Authors: Badadhe P. V. , Chavan N. M. , Mandhane P. G. , Joshi R. S. , Nagargoje D. R. , Gill C. H. 
Published: September 2011

Abstract8 Compounds of type (III), (IV), and (V) are prepared and screened for their antimicrobial activities.
ChemInform Abstract: Importance of an Acid Additive in the Synthesis of Pyrido[1,2‐a]benzimidazoles by Direct Copper‐Catalyzed Amination.
Authors: Masters Kye‐Simeon , Rauws Tom R. M. , Yadav Ashok K. , Herrebout Wouter A. , Van der Veken Benjamin , Maes Bert U. W. 
Published: September 2011

AbstractThe amination is achieved in the presence of catalytic copper and an acid additive.
ChemInform Abstract: Studies on the Palladium‐Catalyzed Direct Alkenylation of 1,2‐Azoles.
Authors: Chappell Ben , Dedman Nathan , Wheeler Simon 
Published: September 2011

AbstractElectron‐rich heterocycles, such as isoxazoles (I), isothiazoles (IV) and pyrazoles (VI) undergo direct Pd‐catalyzed alkenylation in moderate yields.
ChemInform Abstract: Stereoselective Synthesis of Phenyl‐1,2,3‐triazoles Containing (E)‐Vinyl Halide Group via a One‐Pot, Three‐Component Reaction.
Authors: Zhang Wensheng , Su Changhui , Kuang Chunxiang , Yang Qing 
Published: September 2011

AbstractTwo examples are given, where NCS and NIS are used, resulting in the corresponding vinyl chloro and vinyl iodo derivatives, respectively.
ChemInform Abstract: Synthesis and Biological Evaluation of a Novel Human Stem/Progenitor Cells Proliferation Activator: 4‐(4‐(5‐Mercapto‐1,3,4‐oxadiazol‐2‐yl)phenyl)thiosemicarbazide (Stemazole).
Authors: Sun Ying , Wang Wei , Sun Yuanyuan , Han Mei 
Published: September 2011

AbstractStemazole (IXa) and its derivatives are prepared in four steps from methyl aminobenzoates (I) via construction of the oxadiazole ring as the key step.
ChemInform Abstract: L‐Proline as an Efficient Catalyst for the Multi‐Component Synthesis of 6‐Amino‐4‐alkyl/aryl‐3‐methyl‐2,4‐dihydropyrano [2,3‐c]pyrazole‐5‐carbonitriles in Water.
Authors: Mecadon Hormi , Rohman Md. Rumum , Kharbangar Iadeishisha , Laloo Badaker M. , Kharkongor Icydora , Rajbangshi Mantu , Myrboh Bekington 
Published: September 2011

AbstractA four‐component synthesis of title compounds (IV) using L‐proline as a catalyst is established.