bluuebunny/crossref_metadata_2025_split huggingface dataset:
OUTCOME OF TRANSMETATARSAL AMPUTATIONS IN PATIENTS WITH DIABETES MELLITUS: A MULTIDISCIPLINARY FOOT CARE SERVICE APPROACH
Authors: Humphrey J.A. , Kanthasamy S. , Coughlin P. , Coll A. , Robinson A.H.N. 
Published: May 2024

AimThis retrospective case series reports the reoperation, major amputation, survival rates and mobility status in diabetic patients who underwent a trans-metatarsal amputation (TMA) managed within a multi-disciplinary diabetic foot care service.Methods and patientsForty-one consecutive patients (37 men, 4 women) underwent a TMA between January 2008 to December 2017. They were retrospectively reviewed. The mean age at the time of surgery was 63 years (range 39 – 92).ResultsEighty-eight per cent (36/41) of the patients were followed-up. Four (11%) of the 36 patients required reoperation, including three major amputations (8%). All the patients requiring a reoperation were vasculopaths. The four-year patient survival rate following a TMA was 69% (25/36). Ninety-six per cent (21/22) of the surviving patients not requiring revision to a major amputation were fully mobile in bespoke orthoses, of whom a third required a stick.ConclusionThis study shows that transmetatarsal amputation in patients with diabetes, managed in a multi-disciplinary diabetic foot care service, is effective for limb salvage.
MULTICENTRE RANDOMIZED CONTROLLED STUDY OF SUBTALAR ARTHRODESIS USING ALLOSTEM VERSUS AUTOLOGOUS BONE GRAFT
Authors: Coetzee C. , Myerson M. , Anderson J. , McGaver R. Stone 
Published: May 2024

IntroductionAlloStem/Cellular Bone Allograft and autologous bone graft are accepted methods for managing hindfoot degenerative arthritis. The purpose was to evaluate outcomes of AlloStem and autograft in subtalar arthrodesis and compare overall fusion rates.MethodsThis study was conducted in IRB compliance. Patients between 18–80 years who qualified for a subtalar fusion were randomized 1:1 to AlloStem or autologous graft. The AOFAS hindfoot ankle scale, FFI-R and SF-12 were collected pre-operatively, 6 weeks, 3 & 6 months, 1 and 2 year. Weight-bearing 3-view ankle X-rays were done at the same intervals. A CT scan was obtained at 6 months.Results140 patients were enrolled; 124 patients had surgery(60-AlloStem and 64-Control). Withdrawals included 14 voluntarily before surgery and 2 intra-operative failures. 19 were lost to follow-up. Mean age for AlloStem was 56.69(20.3–79.6) and Autograft was 54.60(20.74–80.07). 59 AlloStem patients completed their 6 month visit and 45 completed 2 years. AOFAS score improved: 40.02 at pre-op to 72.16(6 mo) to 79.51 at 1 year and 80.38 at 2 year. SF-12 improved 58.29 at pre-op to 65.67 at 6 month and 71.59 at 2 year. FFI-R improved 236.88 at pre-op to 203.53 at 6 month 149.93 at 2 year.60 Autograft patients completed their 6 month visit and 51 patients completed their 2 year. AOFAS score improved 42.89 at pre-op to 75.67 (6 mo) to 79.75 at 1 year and 78.62 at 2 year. Autograft SF-12 improved 60.55 at pre-op to 70.40 at 6 month and 75.26 at 2 year. Autograft FFI-R improved 217.16 at pre-op to 166.77 at 6 month and 145.43 at 2 year. AlloStem patients had a mean posterior fusion rate of 28.9% at 6 months whereas the Autograft had 46.3%(p=.049). Non-union rates were AlloStem(9/57)(15.7%) whereas Autograft was 3/60(5%).ConclusionAlloStem trended to be inferior to Autologous graft.
AgroGuardian: An All-Terrain Vehicle Crash Detection and Notification System
Authors: Khorsandi Farzaneh , De Moura Araujo Guilherme   , Ferreira Lima dos Santos Fernando   
Published: May 2024

Highlights

Off-road ATV incidents can be problematic due to long EMS alert times.

An ATV crash-detection-and-report system is expected to reduce EMS response time.

The developed system can accurately detect ATV rollovers.

The alert time of our system is 10 times faster than the national U.S. average.

Any rider using our system is 3 times more likely to survive an off-road crash.

Abstract. All-Terrain Vehicle (ATV) incidents are a common cause of injury and death in the agricultural industry in the United States. Many ATV off-road crashes on farms and ranches may result in trauma requiring immediate care, but the injured rider is unable to seek help due to their injuries. Moreover, many of these crashes occur in isolated areas that may be difficult to access and have unreliable cellular phone service, making contact with emergency medical services (EMS) challenging. This study aimed at developing and testing a low-cost ATV crash detection device (AgroGuardian) that immediately alerts EMS and emergency contacts, even when the rider is unable to take action and/or there is no cellular phone service available. AgroGuardian includes an embedded data logging system, a smartphone application, and a remote database. The embedded system includes an Inertial Measurement Unit (IMU) for attitude estimation, a Global Positioning System (GPS) for location estimation, and a Rock7 modem for off-board communication. A smartphone application was developed for the users to input information about their vehicle (e.g., make and model) and emergency contacts. Also, it allows them to interact with their ATV data. An emergency signal along with the ATV’s coordinates is transmitted through the Rock7 modem and received in the remote database when a rollover is detected by the system. This emergency signal is then processed and sent to EMS and emergency contacts. Our results indicated that the device: (1) is unlikely to miss an ATV rollover; (2) has a fast EMS notification time (40.7 s); and (3) the ATV localization system presented an average error of 2.34 m. Keywords: ATV, EMS alert time, Farm, Off-road incidents, Quadbike, Rollover.
Opportunities and risks of using artificial intelligence in primary schools
Authors: Jamiołkowska Ewelina 
Published: May 2024

The dynamic development of artificial intelligence as a technical and scientific field is well known to us. On the educational level, we can increasingly see the testing of new technological possibilities. This mainly concerns the sphere of teaching and learning. The aim of this article is to polemicize on the most important opportunities and risks of using artificial intelligence in primary schools. The use of these tools in education opens up new horizons not only for students, but also for teaching staff. In order to benefit from the full potential of the opportunities offered to us, a thoughtful implementation of artificial intelligence in schools is necessary. This will minimize the risk of failure and increase the resources of modern technology.
Cooperation of the family of a child with disability with the school
Authors: Waszczuk Joanna , Nazaruk Stanisława , Spychel Dominika , Lipińska Ewa 
Published: May 2024

In the process of upbringing and development of programs and environments for a child with a disability are home, kindergarten, and school. Thanks to them, training a young person to participate in life. However, this is not a task, so be careful and deliberately influence the main subjects of education. Referring to the description, a research project was developed, the main purpose of which was to describe the cooperation of teachers and parents of a child with a disability. Research of teachers at secondary schools where teaching is special education. The result of the undertaken searches is the obtained research, saying that there is a social action that affects the results of the family and school is needed, in addition, better prepare the child for life in changing social conditions, in the new shaping of reality and in the game that enters into the need of man.
Sources of exposure to non-tobacco nicotine electronic nicotine delivery systems and associations with susceptibility to use and use behaviors among young adults in the United States
Authors: Li Wei , Kong Grace , Davis Danielle R. , Bold Krysten W. , Krishnan-Sarin Suchitra , Camenga Deepa R. , Morean Meghan E. 
Published: May 2024

Introduction
The Electronic Nicotine Delivery Systems (ENDS) industry recently introduced non-tobacco nicotine (NTN), which is not tobacco-derived and is often marketed as “tobacco-free nicotine.” Given its novelty, it is important to understand where young adults learn about NTN ENDS. This study examined sources of exposure to NTN ENDS and relationships with NTN ENDS use and susceptibility.

Methods
We analyzed online survey data collected in Fall 2021 from 642 young adults (18–25 years) who had heard of NTN ENDS. We assessed 9 sources of NTN ENDS exposure (e.g., retail stores, social media) and examined associations between sources of exposure and NTN current (past-month) use, lifetime (non-current) use, and susceptibility to use, adjusting for demographics and other tobacco product use.

Results
Participants reported current NTN ENDS use (37.4%), lifetime use (12.0%), susceptibility (18.5%), or no susceptibility to use (32.1%). The most common sources of NTN ENDS exposure were retail stores (87.7%) and social media (81.0%). Exposure to NTN ENDS via social media was associated with greater odds of current NTN ENDS use (vs. no susceptibility) (aOR = 1.83, 95%CI: 1.02–3.28). Exposure via online streaming platforms was associated with greater odds of current (aOR = 1.75, 95%CI: 1.08–2.82) and lifetime NTN ENDS use (aOR = 2.42, 95%CI: 1.25–4.68).

Conclusions
Young adults were exposed to and learned about NTN ENDS from diverse sources, primarily retail shops and social media. Further, exposure via social media and streaming platforms were associated with NTN ENDS use. Future studies should explore the content of NTN information from various sources to inform prevention efforts.
Políticas de internacionalização da educação: olhares multidimensionais
Authors: Silva Maria Vieira , Souza Vilma Aparecida de , Souza Raquel Aparecida , Richter Leonice Matilde 
Published: May 2024

Internacionalização, Globalização e Mundialização são categorias analíticas que guardam complexidades, singularidades e similaridades. A epígrafe acima, extraída dos escritos do notável geógrafo brasileiro, Mílton Santos, coloca em evidência um dos aspectos que garantem o elo comum entre os mencionados fenômenos: seu caráter não reificado e, portanto, substantivado nas relações sociais com as demandas de quem constrói o espaço geográfico. Historicamente, dimensões espaciais e geográficas tiveram importante papel no processo de acumulação do capital conduzidas por grupos hegemônicos. Karl Marx e Friedrich Engels, há 176 anos, analisaram com precisão as metamorfoses ensejadas pelos novos mercados financeiros e de consumo, permitindo a acumulação capitalista de forma cosmopolita, por meio de fluxos integradores e da flexibilidade geo-política do mundo:
Marktrecherchen und Informationsrechercheleitfaden für Start-ups (in Deutschland)
Authors: Seidler-de Alwis Ragna 
Published: May 2024

Zusammenfassung
Die Zahl der innovationsorientierten Unternehmensgründungen in Deutschland ist in den letzten Jahren rückläufig. Eine häufige Ursache für das Scheitern von Gründungen ist, dass für die angebotenen Produkte und Dienstleistungen kein Marktbedarf besteht und diesem Thema zu wenig Aufmerksamkeit geschenkt wird. Marktrecherchen sind jedoch eine wichtige Voraussetzung für erfolgreiche Unternehmensgründungen. Daher wird ein Informationsrechercheleitfaden für Marktrecherchen vorgestellt, der ein methodisches und strukturiertes Vorgehen beinhaltet sowie die einzelnen Untersuchungsbereiche im Marktrechercheprozess aufzeigt. Der Informationsrechercheleitfaden basiert auf umfangreichen praktischen und theoretischen Erfahrungen aus dem Hochschul- und Beratungsumfeld. Er wird ergänzt durch eine Literatur- und Informationsressourcenrecherche in Universitätsbibliotheken im Silicon Valley, die ihre Studierenden im Hinblick auf Start-ups von Beginn des Studiums an in vielfältiger Weise erfolgreich unterstützen.
Food habits of invasive masked palm civets (Paguma larvata) in northern Japan
Authors: Shimoyama Mizuki , Tsuji Yamato 
Published: May 2024

Abstract
We examined the feeding habits and seasonal changes in invasive masked palm civets (Paguma larvata) in northern Japan, to understand their feeding strategies. Between 2020 and 2022, we collected 98 fecal samples from masked palm civets and analyzed their content. The civets fed mainly on fruits (78 % in terms of the point-frame method) and arthropods (15 %); fruits were consumed throughout the year, but increased in winter when arthropods were not available. The feeding plasticity of masked palm civets, in addition to their physical and behavioral adaptations, enables them to expand their distribution in introduced habitats in temperate regions.
Role Of Intellectual Property Theories in Addressing Anomalies Created By The Intersection of Artificial Intelligence and Intellectual Property Rights: An Analysis
Authors: Jaiswal Reena , Singh Anu , Rathore Saloni , Verma Alpika , Saxena Prakhar , Mishra Megha , . Moiz 
Published: May 2024

Globally, the use of artificial intelligence (AI) is expanding exponentially. The issue of managing intellectual property in AI is raised by this surge. Discussions and moderating have taken place, but no resolution has been reached. The issue of whether the work created by an AI should get a special status still exists. When it comes to the control of IPR in artificial intelligence, there are a few oddities. The ownership of patents and copyrights is in doubt, and there are serious worries about the consequences of violation. With the development of technology, there is no certainty on the law, despite existing international accords and conventions. In the absence of artificial intelligence (AI), intellectual property (IP) rules have, up to this point, treated IP as a product of human cognition. The current boom in AI, which has seen the development of IP from the "intelligence" of software, has upended this base. But the non availability of law on works created by artificial intelligence the law is left far behind to deal with the anomalies created by the intersection of “Artificial intelligence and intellectual property rights”. This research paper examines the role of intellectual property theories in addressing AI anomalies, focusing on copyright, patent, and trademark laws. It analyzes utilitarianism, labour theory and personality theory, examining authorship and ownership in AI-generated works and potential conflicts between human creators and machine-generated content. In this research paper researcher(s) will- Analyse various theories of Intellectual properties to tackle the anomolities created by the intersection of IPR and AI. Criticize and suggest changes in the theories to make them helpful for emerging frameworks on AI and IPR.
The Structures of Non-Coprime Graphs for Finite Groups from Dihedral Groups with Regular Composite Orders
Authors: Aulia Sita Armi , Wardhana I Gede Adhitya Wisnu , Irwansyah Irwansyah , Salwa Salwa , Misuki Wahyu Ulyafandhie , Nghiem Nguyen Dang Hoa 
Published: May 2024

AbstractFor any finite group, the non-coprime graph of the group is a graph with vertices consisting of all non-identity elements of the group. Two different vertices are considered adjacent if their orders are not coprime, meaning their greatest common divisor (gcd) is not equal to one. Misuki provides the structure of the non-coprime graph for the dihedral group when the order is a prime power. We establish a more general property for cases where the order of the group is a regular composite number, discovering that the structure of the non-coprime graph for a dihedral group can be partitioned into some number of complete subgraphs.Keywords: dihedral group; disjoint subgraph; non-coprime graph. AbstrakUntuk sebarang grup hingga, graf non-coprime dari grup tersebut adalah graf dengan simpul yang terdiri dari semua elemen non-identitas dari grup tersebut. Dua simpul yang berbeda dianggap bertetangga jika orde mereka tidak saling prima, artinya pembagi terbesar bersama (gcd) mereka tidak sama dengan satu. Misuki memberikan struktur graf non-coprime untuk grup dihedral ketika ordenya adalah pangkat prima. Pada studi ini didapatkan sifat yang lebih umum ketika orde grup adalah bilangan komposit biasa. Didapatkan juga bahwa struktur graf non-coprime dari grup dihedral dapat dipartisi menjadi beberapa subgraf lengkap.Kata Kunci: graf non-koprima; grup dihedral; subgraph disjoin. 2020MSC: 05C25, 05C69, 20D60.
Revealing the artemisinin and piperaquine treatment failure: a systematic review
Authors: Farindira Vesti Rahmasari  , Imwong Mallika , Chakim Irfanul , Setyonugroho Winny , Tri Wulandari Kesetyaningsih  , Gunadi Agus , Arisandi Desto 
Published: May 2024

Background: Artemisinin-based combination therapy (ACT) consists of a potent artemisinin component. Since the dihydroartemisinin performance effectiveness depends on piperaquine interaction still challenging, further research needs to establish the current status of artemisinin resistance relative to its geography and recognize any drug resistance interaction between dihydroartemisinin and piperaquine.
Aim: This systematic review was aimed to find out the effect of dihydroartemisinin and piperaquine interaction concerning resistance, recurrence, parasitological failure, clinical failure, parasite clearance time, parasite reduction ratio, cure rate, which may affect treatment failure of patients with uncomplicated P. falciparum.
Method: The article was not limited to year and country. This study analyzed any effect of interaction. Pubmed and Scopus were used as electronic databases, and MeSH terms and keywords were used to find specific studies. A total of 2131 studies were initially identified; however, 20 were eligible for qualitative synthesis.
Result: The dihydroartemisinin piperaquine cure rate reported in Asia and Africa was above 98%. Eight RCTs, eleven prospective cohort studies, and one retrospective and prospective cohort study were included in this review. Design studies did not compare the same anti-malarial drug pattern, so it was difficult to do a pooled analysis. Even though this drug combination did not show a clear description of piperaquine resistance can affect artemisinin resistance, the adequate clinical and parasitological failure (ACPR) from this research reached above 93%, and for early treatment failure (ETF), late clinical failure (LCF), and late parasitological failure (LPF), were almost 0 %.
Conclusion: The dihydroartemisinin-piperaquine combination still has highly efficacious therapy to fight malaria in some areas based on these multiple factors and reviews.
Triple-layered composite mesh for managing anterior abdomen wall defects in ventral hernia
Authors: Tamba Riana Pauline , Candy  , Yani Ahmad , Amaliah Rizky 
Published: May 2024

Introduction: In managing ventral hernia, using mesh for the anterior abdominal wall defect closure has become a standard. Different types of materials have been used as a mesh, each with its own benefits and drawbacks. This study aimed to investigate the potential of a triple-layered composite mesh made from amniotic membrane-coated polypropylene mesh (AMPM) with an adhesion barrier as an alternative for anterior abdominal wall defect closure.
Methods: An experimental study was conducted using Sprague-Dawley mice, imposed with a mechanical ventral hernia and divided into four groups with different treatments: sham surgery, mesh polypropylene, AMPM composite, and AMPM with adhesion barrier (triple-layered composite mesh). After 7 and 30 days of the procedure, the mice were evaluated for the recurrence of anterior abdominal wall defects, the histological profile of polymorphonuclear (PMN) cells, foreign body giant cells (FBGC), fibroblast cells, neovascularization, and adhesion of mesh to surrounding tissue in each group.
Results: No anterior abdominal wall defect recurrence was observed in all groups at 7- and 30-days post-procedure. We found no significant difference in histological profiles of PMN, FBGC, and fibroblast cells from each group. There was a statistically significant difference in the neovascularization (p=0.025) and adhesion (p=0.034) between the polypropylene mesh group and the triple-layered composite mesh group.
Conclusion: Triple-layered composite mesh has the potential to be an alternative to cover anterior abdominal wall defects, with triple-layered composite mesh and AMPM mesh groups showing a significantly higher rate of neovascularization and a lower rate of adhesion than the polypropylene mesh group.
Norepinephrine modified the interaction between Escherichia coli and levofloxacin, potentially affecting clinical outcomes and increasing the risk of bacterial colonization
Authors: Thayyiba Amina , Wasito Eddy Bagus , Alimsardjono Lindawati 
Published: May 2024

Background: Norepinephrine is the most used vasopressor in intensive care units. It can modulate gene expressions and metabolism pathways in Escherichia coli. As fluoroquinolone’s bactericidal activity is affected by bacterial metabolism and growth rate, simultaneous exposure to these medications might alter the interaction between E. coli and levofloxacin. This study aims to investigate the effect of norepinephrine and levofloxacin given simultaneously on the in vitro growth of E. coli.
Methods: Ten clinical isolates of E. coli were grown in minimal nutrition media with and without norepinephrine, levofloxacin, or both. Bacterial growth was observed for 20 h, and viable cell count was done every 2 h. Growth curves and generation times for each study group were calculated. Statistical analysis compared the viable cell counts on the 4, 14, and 20 h observation time points and the generation times.
Results: Temporary inhibition of E. coli growth was observed until 4h of incubation when therapeutic concentrations of norepinephrine and levofloxacin were given simultaneously, followed by regrowth. The viable cell count of the norepinephrine–levofloxacin group was significantly lower than the control group by the 14 h and 20 h time points. Interestingly, the study group's average generation time of regrowth was 19.3 min, which was significantly faster than the control group (p < 0.05).
Conclusion: Norepinephrine caused alterations in the interaction between E. coli and levofloxacin, which may affect clinical outcomes and increase the risk of bacterial colonization in patients receiving simultaneous norepinephrine and levofloxacin therapy.