bluuebunny/crossref_metadata_2025_split huggingface dataset:
A population‐based study of associations between current posttraumatic stress symptoms and current fatigue
Authors: Lerdal Anners , Lee Kathryn A. , Rokne Berit , Knudsen Jr. Øistein , Wahl Astrid K. , Dahl Alv A. 
Published: October 2010

AbstractThis study explores current experience with posttraumatic stress disorder (PTSD) symptoms and other variables (sociodemographic, mental distress, somatic morbidity, self‐rated health, and quality of life [QoL]) in relation to fatigue. A representative sample of the Norwegian population (N = 3,944) was invited to participate in a mailed survey, and 1,857 (47%) returned valid responses on the questionnaire that included the Fatigue Severity Scale and the Posttraumatic Symptom Scale‐10. Posttraumatic stress disorder symptoms showed a strong association with fatigue in univariate (β = .41) and multivariate analyses (β = .33). Associations between psychosocial health variables, QoL, and fatigue were confirmed. However, PTSD symptoms showed the strongest association with fatigue in the analyses. Findings need to be replicated in other population samples and in clinical samples with PTSD and fatigue.
Kinetics of MnO−4 oxidation of succinic acid in aqueous solution of cetyltrimethylammonium bromide
Authors: Malik Maqsood Ahmad , Al‐Nowaiser F. M. , Ahmad Naushad , Khan Zaheer 
Published: October 2010

AbstractThe rate of electron transfer from succinic acid to permanganate increases with an increase in the concentration of cationic surfactant, cetyltrimethylammonium bromide (CTAB). The micellar catalysis is attributed to the formation of an ion pair between CTAB subaggregates and reactants as well as an increase in the concentration (solubilization) of both reactants and/or intermediate in the micellar pseudophase. The effects of inorganic salts (MnCl2, NaF, NaBr, and NaNO3) have also been studied and discussed. The observed results are discussed in terms of the pseudophase model of the micelles proposed by Menger and Portony. Mechanisms consistent with the observed kinetic data have been proposed. © 2010 Wiley Periodicals, Inc. Int J Chem Kinet 42: 704–712, 2010
Synthesis and Properties of Hyperbranched Polyimides Combined with Silica
Authors: Minko Evgenia , Sysel Petr , Hauf Michal , Brus Jiří , Kobera Libor 
Published: October 2010

AbstractSummary: The novel hyperbranched polyimide ‐ silica hybrid materials containing theoretically 16 wt% of an inorganic phase were prepared via a sol‐gel process. An amine terminated polyimide precursor (hyperbranched polyamic acid) was prepared from commercially available monomers 4,4′,4″‐triaminotriphenylmethane and 4,4′‐oxydiphthalic anhydride in molar ratio 1:1. Tetramethoxysilane and/or 3‐glycidoxypropyltrimethoxysilane (also used as a coupling agent) were used as silica precursors. During thermal exposition the polyimide precursor was transformed to hyperbranched polyimide and hydrolyzed alkoxy groups reacted mutually to form silica. The final products were self‐standing films, whose structure was characterized by using IR and 13C and 29Si solid state NMR spectroscopy. The influence of the amount of silica and/or coupling agent on their structure and thermal properties was described.
Presentation, diagnosis, and management of multiple system atrophy in Europe: Final analysis of the European multiple system atrophy registry
Authors: Köllensperger Martin , Geser Felix , Ndayisaba Jean‐Pierre , Boesch Sylvia , Seppi Klaus , Ostergaard Karen , Dupont Erik , Cardozo A. , Tolosa Eduardo , Abele Michael , Klockgether Thomas , Yekhlef Farid , Tison Francois , Daniels Christine , Deuschl Günther , Coelho Miguel , Sampaio Cristina , Bozi Maria , Quinn Niall , Schrag Anette , Mathias Chris J. , Fowler Clare , Nilsson Christer F. , Widner Håkan , Schimke Nicole , Oertel Wolfgang , del Sorbo Francesca , Albanese Alberto , Pellecchia Maria Teresa , Barone Paolo , Djaldetti Ruth , Colosimo Carlo , Meco Giuseppe , Gonzalez‐Mandly Antonio , Berciano Jose , Gurevich Tanya , Giladi Nir , Galitzky Monique , Rascol Olivier , Kamm Christoph , Gasser Thomas , Siebert Uwe , Poewe Werner , Wenning Gregor K. ,   on behalf of the EMSA‐SG
Published: October 2010

AbstractMultiple system atrophy (MSA) is a Parkinson's Disease (PD)‐like α‐synucleinopathy clinically characterized by dysautonomia, parkinsonism, cerebellar ataxia, and pyramidal signs in any combination. We aimed to determine whether the clinical presentation of MSA as well as diagnostic and therapeutic strategies differ across Europe and Israel. In 19 European MSA Study Group centres all consecutive patients with a clinical diagnosis of MSA were recruited from 2001 to 2005. A standardized minimal data set was obtained from all patients. Four‐hundred thirty‐seven MSA patients from 19 centres in 10 countries were included. Mean age at onset was 57.8 years; mean disease duration at inclusion was 5.8 years. According to the consensus criteria 68% were classified as parkinsonian type (MSA‐P) and 32% as cerebellar type (MSA‐C) (probable MSA: 72%, possible MSA: 28%). Symptomatic dysautonomia was present in almost all patients, and urinary dysfunction (83%) more common than symptomatic orthostatic hypotension (75%). Cerebellar ataxia was present in 64%, and parkinsonism in 87%, of all cases. No significant differences in the clinical presentation were observed between the participating countries. In contrast, diagnostic work up and therapeutic strategies were heterogeneous. Less than a third of patients with documented orthostatic hypotension or neurogenic bladder disturbance were receiving treatment. This largest clinical series of MSA patients reported so far shows that the disease presents uniformly across Europe. The observed differences in diagnostic and therapeutic management including lack of therapy for dysautonomia emphasize the need for future guidelines in these areas. © 2010 Movement Disorder Society
Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats
Authors: Yang Hyun , Yoo Yeong‐Min , Jung Eui‐Man , Choi Kyung‐Chul , Jeung Eui‐Bae 
Published: October 2010

AbstractPlasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. NCKX3 (gene SLC24A3), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. NCKX3 transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. Dev. 77:971–977, 2010. © 2010 Wiley‐Liss, Inc.
Solution of quasi‐static large‐strain problems by the material point method
Authors: Beuth L. , Więckowski Z. , Vermeer P. A. 
Published: October 2010

SUMMARYA procedure for solving quasi‐static large‐strain problems by the material point method is presented. Owing to the Lagrangian–Eulerian features of the method, problems associated with excessive mesh distortions that develop in the Lagrangian formulations of the finite element method are avoided. Three‐dimensional problems are solved utilizing 15‐noded prismatic and 10‐noded tetrahedral elements with quadratic interpolation functions as well as an implicit integration scheme. An algorithm for exploiting the numerical integration procedure on the computational mesh is proposed. Several numerical examples are shown. Copyright © 2010 John Wiley & Sons, Ltd.
Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin‐null mice
Authors: Li Dejia , Yue Yongping , Lai Yi , Hakim Chady H , Duan Dongsheng 
Published: October 2010

AbstractThe mechanism of force reduction is not completely understood in Duchenne muscular dystrophy (DMD), a dystrophin‐deficient lethal disease. Nitric oxide regulates muscle force. Interestingly, neuronal nitric oxide synthase µ (nNOSµ), a major source of muscle nitric oxide, is lost from the sarcolemma in DMD muscle. We hypothesize that nNOSµ delocalization contributes to force reduction in DMD. To test this hypothesis, we generated dystrophin/nNOSµ double knockout mice. Genetic elimination of nNOSµ significantly enhanced force in dystrophin‐null mice. Pharmacological inhibition of nNOS yielded similar results. To further test our hypothesis, we studied δ‐sarcoglycan‐null mice, a model of limb‐girdle muscular dystrophy. These mice had minimal sarcolemmal nNOSµ delocalization and muscle force was less compromised. Annihilation of nNOSµ did not improve their force either. To determine whether nNOSµ delocalization itself inhibited force, we corrected muscle disease in dystrophin‐null mice with micro‐dystrophins that either restored or did not restore sarcolemmal nNOSµ. Similar muscle force was obtained irrespective of nNOSµ localization. Additional studies suggest that nNOSµ delocalization selectively inhibits muscle force in dystrophin‐null mice via nitrosative stress. In summary, we have demonstrated for the first time that nitrosative stress elicited by nNOSµ delocalization is an important mechanism underlying force loss in DMD. Copyright © 2010 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
The diagnostic dilemma of congenital unstable hemoglobinopathies
Authors: Yates Amber M. , Mortier Nicole A. , Hyde Kristina S. , Hankins Jane S. , Ware Russell E. 
Published: October 2010

AbstractUnstable hemoglobin variants represent a rare etiology of congenital hemolytic anemia. Without a high index of suspicion, plus proper laboratory testing and interpretation, the correct diagnosis can be elusive. We report on five children who were initially thought to have other congenital disorders such as hereditary spherocytosis or thalassemia, before β‐globin gene sequencing led to the definitive diagnosis. Recognizing the variable clinical presentation and laboratory data reported will aid clinicians in diagnosis of unstable hemoglobins variants in children with atypical forms of hemolytic anemia, particularly those with low pulse oximetry values or whose hemoglobin electrophoresis suggest β‐thalassemia trait. Pediatr Blood Cancer. 2010;55:1393–1395. © 2010 Wiley‐Liss, Inc.
Temsirolimus for metastatic desmoplastic small round cell tumor
Authors: Thijs Anna M.J. , van der Graaf Winette T.A. , van Herpen Carla M.L. 
Published: October 2010

AbstractDesmoplastic small round cell tumor (DSRCT) is a rare and aggressive neoplasm that mostly occurs in young males. No curative treatment options currently exist for this type of tumor and long‐term survival remains poor. In vitro rapamycin induces apoptotic death of JN‐DSRCT‐1 cells, a possible model for desmoplastic small round cell tumors in which the EWS gene is fused to the WT1 gene. We therefore demonstrate the prolonged activity of temsirolimus, an mTOR‐inhibitor, in a patient with DSRCT. Pediatr Blood Cancer. 2010;55:1431–1432. © 2010 Wiley‐Liss, Inc.
Kinetics of nonideal hyperbranched A2+ B3polycondensation: Simulation and comparison with experiments
Authors: Yang Xiaomei , Wang Long , He Xuehao 
Published: October 2010

AbstractTo overcome the deficiency of mean field method in introducing the intramolecular cyclization and the steric effects, the reactive bond fluctuation model was applied to study nonideal hyperbranched A2+ B3polycondensation, which has high sensitivity of gelation to the concentration of monomers, the feed ratio and the reactivity of functional groups. Simulation demonstrated that the mean field theory overestimated hyperbranched polymerization especially at high reaction conversion in the system with low monomer concentration where the intramolecular cyclization and the steric hindrance play crucial influences on molecular weight, molecular weight distribution and gel point (GP). The dependences of GP on the monomer concentration, feed ratio, and the reactivity of groups are clearly shown. We further simulated a specific polycondensation system with aromatic terephthaloyl chloride (TCl, A2) and 1,1,1‐tris(4‐trimethylsiloxyphenyl)ethane (TMS‐THPE, B3) (Macromolecules 2007, 40, 6846) using fitting technology, and estimated molecular weight, molecular weight distribution, GPs, and the conformation of hyperbanched polymer. It provides a feasible way to quantitatively understand hyperbranched polymerization with the reaction specificity. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010
Local enhancement of inelastic tunnelling in epitaxial graphene on SiC(0001)
Authors: Červenka J. , van de Ruit K. , Flipse C. F. J. 
Published: October 2010

AbstractWe have measured the elastic and inelastic tunnelling properties of epitaxial graphene on SiC(0001) using cryogenic scanning tunnelling spectroscopy. We find that the dominant inelastic channel of the out‐of‐plane acoustic graphene phonon at 70 mV is spatially localized to particular regions of the graphene–SiC system that contain localized states. At these locations the maximum inelastic tunnelling channel reaches up to half of the total tunnelling current. The local enhancement of the inelastic tunnelling is found at the localized electron states of the graphene/SiC interface layer. Nonequilibrium Green's function formalism theory calculations indicate that this intense inelastic channel arises from graphene phonon modes strongly coupled to narrow electron states.
Theoretical studies of one‐dimensional C36 coplanar polymers
Authors: Bai Hongcun , Ai Yafan , Huang Yuanhe 
Published: October 2010

AbstractThe structures and electronic, elastic and transport properties of the one‐dimensional coplanar polymers constructed by sharing pentagons or hexagons of C36 cages are investigated using a self‐consistent field crystal orbital method based on density functional theory. It is found that these C36 coplanar polymers are all energetically favourable. The stability of the coplanar polymers is related to the atomic positions in the coalescent region and the size of retained aromatic domains. They are softer than carbon nanotubes due to the smaller Young's moduli. The calculated band structures show that these coplanar polymers can be a metal or a semiconductor. Moreover, the mobility of charge carriers is also calculated based on the deformation potential approach.
Science teachers' views of science and religion vs. the Islamic perspective: Conflicting or compatible?
Authors: Mansour Nasser 
Published: October 2010

AbstractThis paper reports a study that explores Egyptian science teachers' views on religion and science within the context of Islam. It also highlights an ontological and epistemological consideration of these views, particularly the ways through which Egyptian Muslim teachers understand such a relationship with reference to the Qur'anic/Islamic attitude toward science and knowledge. The study built upon Barbour's categorization scheme to guide the data collection and analysis and to guide the interpretation of the teachers' responses in the interviews. Informed by a multigrounded theory of the teachers' views of science and religion, and using Roth and Alexander's analytical framework to interpret how teachers accommodate the relationship between science and religion within their belief system, the findings suggest that participants' views of the relationship between science and a specific religion (Islam) confirmed the centrality of teachers' personal religious beliefs to their own thoughts and views concerning issues of both science and Islam. This centralization, in some cases, appeared to lead teachers to hold a conflicting relationship, hence to a creation of a false contradiction between science and Islam. Therefore, it could be concluded that teachers' personal Islamic‐religious beliefs inform their beliefs about the nature of science and its purpose. © 2010 Wiley Periodicals, Inc. Sci Ed 95:281–309, 2011
Stahlleichtbau mit Verbundelementen
Authors: Lange Jörg , Rack Werner , Kurpiela Aneta , Rädel Felicitas , Hörnel‐Metzger Beate 
Published: October 2010

AbstractDer folgende Beitrag gibt einen Überblick über den Stahlleichtbau mit Verbundelementen. Im Vordergrund stehen hierbei Bauteile mit Blechdicken < 3 mm, die im Verbund mit OSB‐ oder Gipskartonplatten wirken. Durch die Verbundwirkung ergeben sich nennenswerte Verbesserungen der Tragfähigkeit und der Gebrauchstauglichkeit sowie der bauphysikalischen Eigenschaften. Weiterhin werden Sandwichelemente behandelt.Lightweight steel construction with composite elements. This paper contains an overview of lightweight steel structures acting compositely with other materials. Primarily members with wall thicknesses below 3 mm are covered. They act together with OSB‐ or gypsum‐boards. This leads to a significant improvement of the ultimate load as well as of the serviceability and building physics aspects. Furthermore sandwich panels are discussed.
Maxilla–nasion–mandible angle: a new method to assess profile anomalies in pregnancy
Authors: de Jong‐Pleij E. A. P. , Ribbert L. S. M. , Manten G. T. R. , Tromp E. , Bilardo C. M. 
Published: October 2010

AbstractObjectivesTo collect normative data and test the feasibility and reproducibility of measurement of the maxilla–nasion–mandible (MNM) angle between 16 and 36 weeks' gestation and its diagnostic ability in a group of pathological cases.MethodsThe MNM angle is defined as the angle between the intersection of the maxilla–nasion and mandible–nasion lines in the exact mid‐sagittal plane. After assessing reproducibility, the MNM angle was measured in 3D volumes in 241 fetuses cross‐sectionally and in 11 fetuses longitudinally. The MNM angle was then tested in 18 pathological cases with facial malformations or syndromes with specific facial features.ResultsThe MNM angle could be measured in 92.3% of normal fetuses. Intra‐ and interobserver intraclass correlation coefficient (ICC) variability was 0.92 and 0.81, respectively. The difference between paired measurements performed by one or two observers was less than 2.5° and 3.6°, respectively in 95% of the cases. The mean MNM angle was 13.5° and did not change significantly during pregnancy (r = − 0.08, P = 0.25). The MNM angle was above the 95th centile in all cases of retrognathia and maxillary alveolar ridge interruption. The MNM angle was below the 5th centile in Apert syndrome, thanatophoric dysplasia and in two of the three Down syndrome cases.ConclusionsThe feasibility and reproducibility of measurement of the MNM angle is good. The MNM angle can be used to evaluate the convexity of the fetal profile by enabling an objective assessment of the anteroposterior relationship of the jaws and it may therefore be of help in the diagnosis of retrognathia, maxillary alveolar ridge interruption and flat profile. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
Dekontamination von Primärverpackungen mittels Atmosphärendruckplasmen
Authors: Ehlbeck Jörg , Andrasch Mathias , Schnabel Uta , Rackow Kristian , Neumann Torsten , Krohmann Udo , Weltmann Klaus‐Dieter , Großjohann Beatrice , Braun Dagmar , Klein Martin , Schultz Gerd 
Published: October 2010

AbstractZunehmende Transportwege aufgrund sich ausdehnender urbaner Zonen und wachsender Märkte im Zuge der Globalisierung führen zu steigenden Ansprüchen an Verpackungen für verderbliche Produkte. Die Haltbarkeit vieler Produkte wird bestimmt einerseits durch die mikrobiologische Belastung, andererseits durch Diffusion initiierte Abbauprozesse. Auf die Verwendung von Konservierungsstoffen möchte man möglichst verzichten, da diese im Verdacht stehen, allergene Reaktionen auszulösen.Für die antimikrobielle Behandlung der Verpackungen stehen zwei chemische Verfahren zur Verfügung. Das Nassverfahren beruht auf Peressigsäure, wohingegen das Trockenverfahren auf Wasserstoffperoxid beruht. Sowohl in der Lebensmittelindustrie als auch in der Pharmaindustrie möchte man auf die Anwendung von Gefahrstoffen verzichten.Plasma stellt mit seinen vielen antimikrobiell wirkenden Komponenten wie z.B. UV‐Licht und Radikalen eine interessante neue Alternative dar. Bei den Plasmen wird zwischen Niederdruckund Atmosphärendruckplasmen unterschieden. Beide Plasmaarten haben ihre spezifischen Vor‐ und Nachteile. Die Randbedingungen, die an eine antimikrobielle Plasmabehandlung in der Pharmaindustrie gestellt werden, sind eine Kompatibilität mit den vorhandenen Medien wie Strom, Sterilwasser und Sterilluft sowie kompakte Abmessungen.Für die Untersuchungen wurde eine mikrowellenangeregte Laufentladung verwendet. Eine sorgfältige Berechnung der elektrischen Feldverteilung durch numerische Simulation ist erforderlich, um die thermische Belastung der Flaschen zu minimieren. Für eine praktische Umsetzung müssen auch die Prozessnebenzeiten minimiert werden. Hierzu wurde ein barrierefreies Transportsystem entwickelt. Der Einsatz moderner Schaltnetzteiltechnik zur Ansteuerung des Magnetron erlaubt eine schnelle Steuerung des Behandlungsprozesses.Um bei den Behandlungen nicht in den kritischen Temperaturbereich zu gelangen, ist man auf 3 Plasmazyklen von jeweils 300 ms bei einer Leistung von 1000 W limitiert.Unter diesen Bedingungen werden durch die direkte Einwirkung des Plasmas ca. 1–2 lg Mikroorganismen inaktiviert. Bei einer Nachwirkzeit von 5 min können auch bis zu 5 lg Inaktivierung erreicht werden. Daher sind weitere Optimierungen hinsichtlich der Effizienz des Plasmaverfahrens erforderlich.
Beschichtungen und Evakuierung von Vakuum‐Solarkollektoren
Authors: Mientkewitz G. , Keinert F. , Zabel J. , Yudin A. 
Published: October 2010

AbstractNARVA, ein Hersteller von Leuchtstofflampen, begann 2005 mit der Entwicklung eines Vakuumabsorberrohres zum Sammeln von Sonnenenergie zur Heizung und Prozesswärme. Die Hüllrohre werden selbst gefertigt. Nachteile des NARVA Glases wurden durch Beschichtung mit Siliziumdioxid‐Nanoteilchen beseitigt. Sehr hohe Transmission, eine geringere Korrosion und günstiges Bruchverhalten konnten ermöglicht werden. Interessant bei der Entwicklung des Vakuumprozesses ist ein „Lichtofen”︁. Durch die Nutzung von Licht war es möglich, die erforderliche Desorptionstemperatur und damit ein effektives Entfernen von Wassermolekülen als Voraussetzung zur Sicherung des Zielvakuums zu erreichen.