bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Response to OROS‐Methylphenidate Treatment Moderated by Treatment with Antidepressants or Psychiatric Comorbidity? A Secondary Analysis from a Large Randomized Double Blind Study of Adults with ADHD
Authors: Biederman Joseph , Mick Eric , Spencer Thomas , Surman Craig , Faraone Stephen V. 
Published: August 2011

SUMMARYAims: The main aim of this post hoc analysis was to evaluate whether response to osmotic release oral system (OROS) methylphenidate (OROS‐MPH) was moderated by the concomitant use of antidepressants in attention‐deficit/hyperactivity disorder (ADHD) adults stabilized on these medicines for the treatment of depression or anxiety disorders, or a history of mood, anxiety, or substance use disorders. Methods: Two hundred and ninety‐six subjects were screened for participation; 227 were randomized (112 to OROS‐MPH and 115 to placebo), and 223 were analyzed (N= 109 and N= 114 for OROS‐MPH and placebo, respectively). Subjects with anxiety disorders and depression treated with a stable medication regimen of non‐MAOI antidepressants or benzodiazepines for at least 3 months could be enrolled in the study. Subjects currently receiving pharmacotherapy for anxiety disorders or depression were required to have Hamilton‐Depression and Hamilton‐Anxiety rating scales below 15 (mild range). Results: Concomitant antidepressant use at baseline was not associated with ADHD response, OROS‐MPH dose, study completion rate, adverse effects, or exacerbation of anxiety/depression. We did find nominally significant evidence that a lifetime history of mood (P= 0.09) or anxiety (P= 0.04) disorders was a moderator of ADHD symptoms and that a lifetime history of substance use disorder (P= 0.02) was a potential moderator of dose at endpoint. Discussion and Conclusions: We found few moderating effects in this large clinical trial of OROS‐MPH in adults with ADHD, which supports the robustness of the clinical response to OROS‐MPH in adult ADHD despite variable clinical pictures.
Role of receptors of advanced glycation end‐products (RAGE) in type 2 diabetic and non‐diabetic individuals with chronic periodontal disease: an immunohistochemical study
Authors: Rajeev Karattuparambath , Karthika Rajeev , Mythili Ramachandran , Krishnan Viswanathan , Nirmal Madhavan 
Published: August 2011

AbstractAim:  The relationship between diabetes and periodontal disease is well established. It has been shown that advanced glycation end‐products might exert noxious effects on several tissues of the body through its receptor. Evidence for the role of receptors of advanced glycation end‐products in periodontal disease for diabetes is limited, and their presence in human gingival tissues has been demonstrated in few studies. In this study, we demonstrate the presence of receptors of advanced glycation end‐products in patients with chronic periodontitis, with and without type 2 diabetes.Methods:  Gingival biopsies from 19 patients with both type 2 diabetes and chronic periodontitis, and 18 healthy controls with chronic periodontitis, were immunohistochemically stained for receptors of advanced glycation end‐products.Results:  On immunohistochemical analysis, positive staining for receptors of advanced glycation end‐products was seen in the endothelium and the basal and spinous layers of the inflamed gingival epithelium in both type 2 diabetes and non‐diabetes tissue, with a statistically‐significant difference between both groups (P < 0.05).Conclusions:  There was a significant difference in receptors of advanced glycation end‐product immune reactivity between both groups. Receptors of advanced glycation end‐product increase in type 2 diabetes gingival tissue might indicate possible involvement of this receptor in periodontal destruction in individuals with type 2 diabetes.
Investigation of the incidence of stylohyoid ligament calcifications with panoramic radiographs
Authors: Öztaş Bengi , Orhan Kaan 
Published: August 2011

AbstractAim:  This study examined and classified patients who were treated at the Faculty of Dentistry at Ankara University Dentistry to determine the incidence of different types of stylohyoid ligament calcification (SLC) using panoramic radiographs. In addition, it also assessed the possible causative symptoms and Eagle’s syndrome in cases of styloid process elongation.Methods:  The study consisted of 2000 patients (1161 females and 839 males), aged 3–88 years, who were treated at our clinic. The panoramic radiographs were evaluated as part of this study.Results:  Panoramic radiography examination revealed SLC in 1350 patients. Both‐sided (right and left), type 1 SLC was observed in 345 patients, while types 2–4 were found in 203, 418, and 384 patients, respectively.Conclusion:  The incidence of SLC was found to be higher in female patients when compared to male patients. In addition, calcifications were seen more often at age 50–59 years, and the incidence of calcification was found to increase with age. Two Eagle’s syndrome cases were diagnosed among a total of 2000 patients. Finally, it was determined that the incidence of calcified stylohyoid ligament is higher in patients with systemic diseases.
Persistent endometrial cups in the same mare in two successive pregnancies
Authors: Allen W. R. , Wilsher S. 
Published: August 2011

SummaryWe report upon an ageing Thoroughbred mare which showed remarkably similar and abnormally prolonged profiles of equine Chorionic Gonadotrophin (eCG) in her bloodstream during successive pregnancies sired by the same stallion. The first pregnancy was aborted at Day 75 after ovulation in conjunction with a precipitous decline in eCG concentrations which occurred immediately after the peak level had been reached. The second pregnancy, which proceeded safely to term, also involved a similar sharp fall in eCG concentrations after attainment of the peak values. Possible causes of the extended lifespan of the eCG‐secreting endometrial cups in this animal are discussed.
Equine amnionitis and fetal loss: Mare abortion following experimental exposure to Processionary caterpillars (Ochrogaster lunifer)
Authors: CAWDELL‐SMITH A. J. , TODHUNTER K. H. , ANDERSON S. T. , PERKINS N. R. , BRYDEN W. L. 
Published: August 2011

SummaryReasons for performing study: In Australia, there have been recent reports of unusual abortions in mid‐ to late‐gestation mares. These were clinically distinct from other recognised causes of pregnancy loss and the term ‘equine amnionitis and fetal loss’ (EAFL) was adopted to describe this syndrome. Initial investigations concluded that possible causal factors included the presence on affected stud farms of Processionary caterpillars (Ochrogaster lunifer).Objectives: To determine if exposure of pregnant mares to Processionary caterpillars or their shed exoskeletons can induce EAFL.Methods: Processionary caterpillars and their shed exoskeletons were collected and stored frozen. Mid‐gestation mares were dosed with a slurry of caterpillars or shed exoskeleton by nasogastric intubation. Their clinical responses and times to abortion were recorded. All aborted fetuses were autopsied and samples taken for bacteriological and virological culture and histopathology.Results: Intubating mares in mid‐pregnancy with preparations of either whole Processionary caterpillars or shed caterpillar exoskeletons induced abortion with few impending clinical signs. The gross pathological and bacteriological findings of the aborted fetuses were similar to those observed in field cases of EAFL.Potential relevance: Possible exposure to Processionary caterpillars should be considered when examining cases of fetal loss in the mare. The present results provide a starting point to further explore the aetiology and pathogenesis of EAFL.
State Uncertainty Propagation in the Presence of Parametric
Uncertainty and Additive White Noise
Authors: Konda Umamaheswara , Singla Puneet , Singh Tarunraj , Scott Peter D. 
Published: August 2011

Abstract
The focus of this work is on the development of a framework permitting the unification of generalized polynomial chaos (gPC) with the linear moment propagation equations, to accurately characterize the state distribution for linear systems subject to initial condition uncertainty, Gaussian white noise excitation and parametric uncertainty which is not required to be Gaussian. For a fixed value of parameters, an ensemble of moment propagation equations characterize the distribution of the state vector resulting from Gaussian initial conditions and stochastic forcing, which is modeled as Gaussian white noise. These moment equations exploit the gPC approach to describe the propagation of a combination of uncertainties in model parameters, initial conditions and forcing terms. Sampling the uncertain parameters according to the gPC approach, and integrating via quadrature, the distribution for the state vector can be obtained. Similarly, for a fixed realization of the stochastic forcing process, the gPC approach provides an output distribution resulting from parametric uncertainty. This approach can be further combined with moment propagation equations to describe the propagation of the state distribution, which encapsulates uncertainties in model parameters, initial conditions and forcing terms. The proposed techniques are illustrated on two benchmark problems to demonstrate the techniques’ potential in characterizing the non-Gaussian distribution of the state vector.
Digestive performance in neonatal Southern Pacific Rattlesnakes (Crotalus oreganus helleri)
Authors: LaBonte J.P. , Welch K.C. , Suarez R.K. 
Published: August 2011

Despite significant research on the metabolic characteristics of digestion in adult snakes, the digestive performance of neonatal snakes is poorly characterized. We examined the energetic costs associated with digestion and the energetic profit derived from the first meal eaten by neonatal Southern Pacific Rattlesnakes ( Crotalus oreganus helleri Meek, 1905). Composition of venom of C. o. helleri changes through ontogeny, becoming richer in proteolytic components that are hypothesized by some to enhance the rate of digestion. Therefore, we also investigated whether venom type (proteolytic-component-rich “adult” versus neurotoxin-rich “neonate” venom) affected digestive performance. We examined specific dynamic action (SDA), apparent assimilation efficiency, rate of digestion, and gut passage time in snakes fed prey killed with either “adult” or “neonate” venom at 22 and 30 °C. Although digestion progressed more quickly at 30 °C compared with 22 °C, there were no significant differences in digestion rate or assimilation efficiency owing to venom type; however, our statistical power was limited by small sample size. Despite the lack of “digestive experience”, the apparent assimilation efficiency was remarkably high (mean of 92%) and greater than published values for Crotalinae species. Based on these results, we hypothesize that neonatal C. o. helleri make a big energetic profit from their first meal by digesting efficiently and economically.
A 4-year study of invasive and native spider populations in Maine
Authors: Jakob Elizabeth M. , Porter Adam H. , Ginsberg Howard , Bednarski Julie V. , Houser Jeremy 
Published: August 2011

Invasive spiders pose potential threats to native spiders. In 2002, the European spider Linyphia triangularis (Clerck, 1757) (Araneae: Linyphiidae) was discovered in all but one county in Maine. At Acadia National Park, we conducted a 4-year study of L. triangularis and three native linyphiid species of a similar size ( Frontinella communis (Hentz, 1850), Pityohyphantes subarcticus Chamberlin and Ivie, 1943, and Neriene radiata (Walckenaer, 1842)). Using line-transect surveys, we measured population densities in coastal and forest habitat. The density of L. triangularis varied across years but was always significantly higher on the coast than in the forest. In contrast, only one native species was present on the coast and at very low numbers. Coastal L. triangularis were larger and in better condition than those in the forest, and numbers and biomass of insect prey were also higher on the coast. In 2 years, we also conducted transects at a second coastal location in Maine where the invader was at low density. At that site, native densities were substantially higher than at either Acadia site. Our data are consistent with the hypothesis that L. triangularis is reducing populations of native spiders. Companion studies suggest that L. triangularis negatively impacts natives by usurping both web sites and webs.
Chapter 10 Tectonostratigraphy of the greater Barents Sea: implications for petroleum systems
Authors: Henriksen E. , Ryseth A. E. , Larssen G. B. , Heide T. , Rønning K. , Sollid K. , Stoupakova A. V. 
Published: August 2011

Abstract
Palaeogeographic and tectono-stratigraphic considerations in the greater Barents Sea show that the distribution of reservoirs and hydrocarbon source rocks from the Late Palaeozoic to the Palaeogene can be related to three tectonic phases. Firstly, the Palaeozoic Caledonain Orogeny caused uplift to the west, followed by eastward sediment distribution across the shelf, towards carbonate platforms to the east. Secondly the Late Palaeozoic–Mesozoic Uralide Orogeny induced uplift to the east, causing widespread clastic deposition and reversal of the sediment distribution pattern. Thirdly, major Late Mesozoic–Cenozoic rifting and crustal breakup in the western Barents Sea led to the current basin configuration. Reservoir rocks comprise Late Palaeozoic carbonates and spiculites, Mesozoic terrestrial and marine sandstones and Palaeogene deep-water sandstones. Hydrocarbon source rocks range in age from Silurian to Early Cretaceous, and are grouped into three petroleum systems derived from Late Palaeozoic, Triassic and Late Jurassic source rocks. Multiple tectonic episodes caused formation of a variety of trap types, of which extensional fault blocks and gently folded domes have been the most prospective. Volumetric considerations of generated petroleum indicate that charging is not a limiting factor, except in the western margin.
Chapter 11 Structural interpretation of the Barents and Kara Seas from gravity and magnetic data
Authors: Werner Stephanie C. , Ebbing Jörg , Litvinova Tamara P. , Olesen Odleiv 
Published: August 2011

Abstract
New gravity and magnetic anomaly maps for the Barents and Kara Sea region only allow mapping of tectonic features where the thick sedimentary cover is tectonically disturbed. Maps of sedimentary thickness and depth to top basement and the Moho differ between the western and eastern Barents Sea, although detailed thickness and depth estimates require calibration by seismic data. Internal plate boundaries created during the amalgamation of the Barents Sea region were not detected using potential field data.
Chapter 22 Oil and gas potential of the Russian Arctic Shelf and palaeogeographical mapping of the Barents Sea
Authors: Kaminsky V. D. , Suprunenko O. I. , Suslova V. V. 
Published: August 2011

Abstract
The main part of the hydrocarbon resources and reserves of the Russian Arctic Shelf is concentrated in the Barents (with Pechora) and Kara seas. These resources and reserves are mainly represented by gas. Only this part of the Russian Arctic Shelf is ready for development. The geological models of the vast eastern part of the shelf and subsequent quantitative assessments of hydrocarbon resources based on them are rough estimations. Some lithofacies and palaeographic maps illustrate the key stages of the Palaeozoic–Mesozoic geological evolution of the Barents–Kara sea areas.
Chapter 23 Geological model and oil and gas potential of the Gydan–Yuratskiy region and the southern part of the Kara Shelf
Authors: Ivanova N. M. , Belyaev I. V. , Kolesnikova Y. V. 
Published: August 2011

Abstract
The area under consideration covers the Gydan–Yuratsk shallow waters, the southern part of the Kara shelf and the coastal parts of the Yamal, Yavai and Gydan peninsulas. In 2006–2007 Sevmorgeo conducted seismic surveys offshore the Gydan and Yuratskiy bays and in addition regional profiles in the southern part of the Kara Shelf were processed. The high-quality seismic data, their processing and interpretation with the onshore lines and an integrated interpretation with gravimetric–magnetic survey data allowed a unified geological model of the Gydan–Yuratsk region and southern part of the Kara Shelf to be made, aiding the evaluation of the oil and gas potential.
Chapter 25 Tectonic setting, structure and petroleum geology of the Siberian Arctic offshore sedimentary basins
Authors: Drachev Sergey S. 
Published: August 2011

Abstract
The paper summarizes the results of geological and geophysical studies of the Siberian Arctic Shelf (Laptev, East Siberian and Chukchi seas), which is one of the largest continental shelves on Earth. This region consists of as many as 22 significant sedimentary basins of variable age and genesis which are expected to bear significant undiscovered volumes of hydrocarbons. Two major groups of the basins are identified based on the age of the underlying crustal basement: (1) post-Hauterivian/Barremian basins resting on the Late Mesozoic folded basement; and (2) older (Late Palaeozoic to Early Mesozoic?) basins preserved outboard of the Late Mesozoic deformational front in the northern part of the East Siberian and Chukchi seas. At least two significant tectonic events caused the overall tectonic pattern of the shelf as well as formation and structural styles of its individual crustal domains and the sedimentary basins: (1) Late Mesozoic convergence and subsequent collision of the Arctic Alaska–Chukchi Microplate with the Verkhoyansk–Kolyma/Omolon margin of the North Asia Continent around 130–125 Ma (the Verkhoyansk–Brookian compressional event); and (2) a series of Cretaceous and Cenozoic extensional events related to the origin of the Arctic oceanic basins. Based on 2D regional multichannel seismic reflection data constrained by onshore geology, plate tectonic models and inter-regional correlations, as well as on gravity and magnetic grids, the structural styles, lithostratigraphy and possible hydrocarbon systems of the offshore sedimentary basins are considered.
Chapter 32 Geology and petroleum potential of the Arctic Alaska petroleum province
Authors: Bird Kenneth J. , Houseknecht David W. 
Published: August 2011

Abstract

The Arctic Alaska petroleum province encompasses all lands and adjacent continental shelf areas north of the Brooks Range–Herald Arch orogenic belt and south of the northern (outboard) margin of the Beaufort Rift shoulder. Even though only a small part is thoroughly explored, it is one of the most prolific petroleum provinces in North America with total known resources (cumulative production plus proved reserves) of
c
. 28 BBOE. The province constitutes a significant part of a displaced continental fragment, the Arctic Alaska microplate, that was probably rifted from the Canadian Arctic margin during formation of the Canada Basin. Petroleum prospective rocks in the province, mostly Mississippian and younger, record a sequential geological evolution through passive margin, rift and foreland basin tectonic stages. Significant petroleum source and reservoir rocks were formed during each tectonic stage but it was the foreland basin stage that provided the necessary burial heating to generate petroleum from the source rocks. The lion's share of known petroleum resources in the province occur in combination structural–stratigraphic traps formed as a consequence of rifting and located along the rift shoulder. Since the discovery of the super-giant Prudhoe Bay accumulation in one of these traps in the late 1960s, exploration activity preferentially focused on these types of traps. More recent activity, however, has emphasized the potential for stratigraphic traps and the prospect of a natural gas pipeline in this region has spurred renewed interest in structural traps. For assessment purposes, the province is divided into a Platform assessment unit (AU), comprising the Beaufort Rift shoulder and its relatively undeformed flanks, and a Fold-and-Thrust Belt AU, comprising the deformed area north of the Brooks Range and Herald Arch tectonic belt. Mean estimates of undiscovered, technically recoverable resources include nearly 28 billion barrels of oil (BBO) and 122 trillion cubic feet (TCF) of nonassociated gas in the Platform AU and 2 BBO and 59 TCF of nonassociated gas in the Fold-and-Thrust Belt AU.
Chapter 34 Geology and petroleum potential of the rifted margins of the Canada Basin
Authors: Houseknecht David W. , Bird Kenneth J. 
Published: August 2011

Abstract
Three sides of the Canada Basin are bordered by high-standing, conjugate rift shoulders of the Chukchi Borderland, Alaska and Canada. The Alaska and Canada margins are mantled with thick, growth-faulted sediment prisms, and the Chukchi Borderland contains only a thin veneer of sediment. The rift-margin strata of Alaska and Canada reflect the tectonics and sediment dispersal systems of adjacent continental regions whereas the Chukchi Borderland was tectonically isolated from these sediment dispersal systems. Along the eastern Alaska–southern Canada margin, termed herein the ‘Canning–Mackenzie deformed margin’, the rifted margin is deformed by ongoing Brooks Range tectonism. Additional contractional structures occur in a gravity fold belt that may be present along the entire Alaska and Canada margins of the Canada Basin. Source-rock data inboard of the rift shoulders and regional palaeogeographic reconstructions suggest three potential source-rock intervals: Lower Cretaceous (Hauterivian–Albian), Upper Cretaceous (mostly Turonian) and Lower Palaeogene. Burial history modelling indicates favourable timing for generation from all three intervals beneath the Alaska and Canada passive margins, and an active petroleum system has been documented in the Canning–Mackenzie deformed margin. Assessment of undiscovered petroleum resources indicates the greatest potential in the Canning–Mackenzie deformed margin and significant potential in the Canada and Alaska passive margins.
Chapter 36 Petroleum prospectivity of the Triassic–Jurassic succession of Sverdrup Basin, Canadian Arctic Archipelago
Authors: Embry Ashton 
Published: August 2011

Abstract
The Sverdrup Basin of the Canadian Arctic Archipelago is an established petroliferous, rift/sag basin with 17 discovered oil and gas fields. Almost all the hydrocarbons occur in Triassic–Jurassic shallow marine sandstones and were sourced from Middle to Upper Triassic bituminous shales. The discovered fields occur on the culminations of Palaeogene structures. Three prospective areas for future discoveries in the Triassic–Jurassic succession include western Sverdrup, southeastern Sverdrup and the Fosheim Peninsula area. Most of the large structures in these prospective areas were mapped and tested in the initial round of hydrocarbon exploration. The largest potential play which has not been tested involves a stratigraphic component as part of the hydrocarbon trapping mechanism. Potential reservoir units are developed on the third-order sequence scale and 22 such sequences have been delineated in the Triassic–Jurassic succession. Most of them contain a progradational, shallow marine sandstone unit which is in part porous within the prospective areas. These units are often truncated by unconformities on the basin margins and change facies to nonporous strata basinward. The pinchouts of these porous units in proper structural orientations provide good petroleum prospects because they were already present during the maturation and migration of the Triassic-sourced hydrocarbons.