bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physiological and Pathophysiological Implications of Social Stress in Mammals
Authors: Sapolsky Robert M. 
Published: December 2010

AbstractThe sections in this article are:Social Subordinance as an Environmental StressorVarieties of Hierarchical Ranking Systems among MammalsWhat Is Stressful about Having a Particular Social Rank in a Hierarchy?The Adrenocortical AxisCardiovascular Function and DiseaseReproductive PhysiologyFemalesMalesImmunityLimits to the Importance of RankThe Societal Context of RankThe Personal Experience of RankPersonalityConclusions and Relevance to Humans
Saturated‐efferocytosis generates pro‐resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids
Authors: Schif‐Zuck Sagie , Gross Nufar , Assi Simaan , Rostoker Ran , Serhan Charles N. , Ariel Amiram 
Published: December 2010

AbstractDuring the resolution phase of inflammation, apoptotic leukocytes are efferocytosed by macrophages in a nonphlogistic fashion that results in diminished responses to bacterial moieties and production of anti‐inflammatory cytokines. Complement receptor 3 and pro‐resolving lipid mediators promote the engulfment of apoptotic leukocytes by macrophages. Here, we present evidence for the emergence of pro‐resolving, CD11blow macrophages in vivo during the resolution of murine peritonitis. These macrophages are distinct from the majority of peritoneal macrophages in terms of their functional protein expression profile, as well as pro‐resolving properties, such as apoptotic leukocyte engulfment, indifference to TLR ligands, and emigration to lymphoid organs. Notably, we also found macrophages convert from the CD11bhigh to the CD11blow phenotype upon interaction with apoptotic cells ex vivo. In addition, we found that the pro‐resolving lipid mediators resolvin E1 and D1, and the glucocorticoid dexamethasone regulated pro‐resolving macrophage functions in vivo. This regulation culminated in a novel pro‐resolving function, namely reducing the apoptotic leukocyte ingestion requirement for CD11blow macrophage generation. These new phenotype and molecular pathway markers define the new satiated macrophage. Thus, we suggest that satisfying efferocytosis generates CD11blow macrophages that are essential for complete nonphlogistic containment of inflammatory agents and the termination of acute inflammation.
Electrochemical and Structural Characterization of Tri‐ and Dithioether Copper Complexes
Authors: Martínez‐Alanis Paulina R. , Ugalde‐Saldívar Víctor M. , Castillo Ivan 
Published: December 2010

AbstractTri‐ and dithioethers tris(2‐tert‐butyl‐4‐methylphenylthiomethyl)amine (1), bis(2,4‐dimethylphenylthio)methane (2), and bis(2‐tert‐butyl‐4‐methylphenylthio)methane (3) were developed to evaluate their coordination properties toward Cu+. The thioethers associate weakly with Cu+ when ClO4– or PF6– are the counterions, while the reactions with CuI afford crystalline products in the case of nitrilotrithioether 1 and dithioether 2. The solid‐state structures of the complexes [(1)CuI]2 and [(2)(CuI)4(CH3CN)2]2·2THF·4CH3CN are characterized by the chelating‐bidentate coordination mode of 1 and the bridging nature of 2 spanning two Cu4I4 cuboidal clusters. Electrochemical studies of the thioether/Cu+ complexes revealed that the sulfur‐rich coordination environment results in high redox potentials for the Cu2+/Cu+ couple, which is close to the first oxidation potential of the ligands. Thus, chemical (Cu2+) or electrochemical oxidation of the thioethers resulted in oxidative decomposition of the ligands with concomitant reduction to Cu+, in agreement with the electrochemical results. Bulk electrolyses of the tri‐ and dithioethers 1–3 enabled us to confirm that the corresponding disulfides are the major oxidation products. The cathodic peak potentials for the Cu+/Cu0 couple of the complexes allowed us to determine the relative stability of the thioether/Cu+ complexes.
Supramolecular and Intramolecular Energy Transfer with Ruthenium–Anthracene Donor–Acceptor Couples: Salt Bridge versus Covalent Bond (Eur. J. Inorg. Chem. 35/2010)
Authors: Freys Jonathan C. , Wenger Oliver S. 
Published: December 2010

AbstractThe cover picture shows two energy‐transfer dyads that both comprise a ruthenium donor and an anthracene acceptor. The time constant (τ) associated with the energy transfer process is strongly dependent on the linkage between the donor and the acceptor: A salt bridge mediates energy transfer with τ = 153 ns, while a covalent p‐xylene linker makes energy transfer possible within less than 10 ns. Details are discussed in the article by J. C. Freys and O. S. Wenger on p. 5509 ff.
Refining of Roundup Ready® soya bean oil: Effect on the fatty acid, phytosterol and tocopherol profiles
Authors: Costa Joana , Amaral Joana S. , Mafra Isabel , Oliveira M. Beatriz P. P. 
Published: December 2010

AbstractIn this study, genetically modified (GM) soya bean seeds with the event known as Roundup Ready® were used for the production of soya bean oil and their fatty acid, phytosterol and tocopherol composition was characterised. Since these compounds can be partially lost during refining, this study also aimed at evaluating the compositional changes along the GM soya bean oil extraction and refining processes carried out industrially. During the refining process of crude soya bean oil, neutralisation was responsible for the major losses on phytosterols (15%). The greatest reduction of tocopherols was also caused by the neutralisation step (20%), while the deodorisation step caused minor losses (9%). Along the refining process, the decreases of total phytosterols and total tocopherols were 20 and 30%, respectively, which are lower than the losses reported in other studies, reflecting the industrial improvements in preserving beneficial health compounds in the refined oil. The results showed that the refined GM soya bean oil presented higher contents of phytosterols (313 mg/100 g) and tocopherols (931 mg/kg) comparing to other reports.
Multidentate Pyridyl‐Based Ligands in the Coordination‐Driven Self‐Assembly of Palladium Metallo‐Macrocycles
Authors: Brusilowskij Boris , Schalley Christoph A. 
Published: December 2010

AbstractIn the current study, a convenient way is presented to synthesize one ditopic and two tetratopic pyridine‐based ligands, which are then used to construct metallo‐supramolecular polygons. The tetratopic ligands offer two different metal‐binding sites, one central 2,2′‐bipyridine, which can act as a chelate ligand, and two separate pyridine rings, which mediate assembly formation. The three ligands differ with respect to their conformational flexibility. While a biphenyl core allows the ligand to adjust its conformation as needed, a bipyridine core strongly prefers a divergent arrangement of the additional pyridine binding sites, but can be fixed in a cisoid conformation by metal complexation to the bipyridine.Instead, a phenanthroline core already fixes the pyridinylethynyl substituents in a cisoid structure without any metal coordinated to it. Upon mixing each one of the ligands separately with the appropriate amount of dpppPdII triflate, discrete self‐assembled metallo‐macrocycles are formed which are characterized by 1H and 31P NMR spectroscopy and mass spectrometry. Mixing all three ligands simultaneously with the metal complex leads to the formation of a statistical dynamic combinatorial library (DCL) of all possible homo‐ and heterodimeric metallo‐supramolecular assemblies. This underlines the conformational differences between the three ligands not to impact significantly on the self‐assembly process.
A novel role of prostaglandin E2 in neuropathic pain
Authors: Kunori Shunji , Matsumura Shinji , Okuda‐Ashitaka Emiko , Katano Tayo , Audoly Laurent P , Urade Yoshihiro , Ito Seiji 
Published: December 2010

AbstractNeuropathic pain produced by damage to or dysfunction of the nervous system is a common and severely disabling state that affects millions of people worldwide. Recent evidence indicates that activated microglia are key cellular intermediaries in the pathogenesis of neuropathic pain and that ATP serves as the mediator. However, the in vivo mechanism underlying the retention of activated microglia in the injured region has not yet been completely elucidated. Prostaglandin E2 (PGE2) is the principal proinflammatory prostanoid and plays versatile roles by acting via four PGE receptor subtypes, EP1‐EP4. In the present study, we investigated the role of PGE2 in spinal microglial activation in relation to neuropathic pain by using genetic and pharmacological methods. Mice deficient in microsomal prostaglandin E synthase‐1 impaired the activation of microglia and the NMDA‐nitric oxide (NO) cascade in spinal neurons in the dorsal horn and did not exhibit mechanical allodynia after peripheral nerve injury. The intrathecal injection of indomethacin, a nonsteroidal anti‐inflammatory drug, ONO‐8713, a selective EP1 antagonist, or 7‐nitroindole, a neuronal NO synthase inhibitor, attenuated mechanical allodynia and the increase in activated microglia observed in the established neuropathic‐pain state. We further demonstrated that ATP‐induced microglial migration was blocked in vitro by PGE2 via EP2 and by S‐nitrosoglutathione, an NO donor. Taken together, the present study suggests that PGE2 participated in the maintenance of neuropathic pain in vivo not only by activating spinal neurons, but also by retaining microglia in the central terminals of primary afferent fibers via EP2 subtype and via EP1‐mediated NO production. ©2010 Wiley‐Liss, Inc.
The role of TLR2 in nerve injury‐induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response
Authors: Shi Xiang Qun , Zekki Hakima , Zhang Ji 
Published: December 2010

AbstractActivation of macrophages/microglia via toll‐like receptors (TLRs) plays an important role in inflammation and host defense against pathogens. Pathogen‐associated molecular patterns bind TLRs, thereby triggering NF‐κB signaling and production of proinflammatory cytokines. Recent data suggest that nonpathogenic molecules resulting from trauma can also trigger inflammation via TLRs. We sought to determine whether peripheral nerve injury could induce the expression of TLR2 on the site of injury‐damaged nerves and/or in the central nervous system and to investigate whether TLR2 is necessary for the development of nerve injury‐induced neuropathic pain. We observed a significant increase in TLR2, IκB‐α, and TNF‐α mRNAs in damaged nerves. Increased inflammation‐related molecules were found essentially on ED1+ macrophages. Expression of both IκB‐α and TNF‐α in peripheral injured nerves was reduced in TLR2 deficient mice where the recruitment of ED1+ cells is significantly impaired. Although after peripheral nerve injury, spinal microglia became highly activated showing an increase in Iba‐1 immunoreactivity and an enlargement of their cell bodies, neither TLR2 mRNA nor IκB‐α mRNA was detected in activated microglia. Nerve injury‐evoked spinal microglial activation was not significantly altered in TLR2 KO mice. Paw withdrawal threshold and latency in response to mechanical and heat stimuli, respectively, decreased shortly after nerve lesion in wild type mice. In TLR2 KO mice, nerve injury‐induced thermal hyperalgesia was completely abolished contrary to that seen in wild‐type mice, whereas mechanical allodynia was partially reduced. We suggest that TLR2 is necessary for the development of neuropathic pain and its contribution is more important in thermal hypersensitivity than that of mechanical allodynia. ©2010 Wiley‐Liss, Inc.
Mesenchymal stem cells facilitate axon sorting, myelination, and functional recovery in paralyzed mice deficient in Schwann cell‐derived laminin
Authors: Carlson Karen B. , Singh Prabhjot , Feaster Moses M. , Ramnarain Anita , Pavlides Constantine , Chen Zu‐Lin , Yu Wei‐Ming , Feltri M. Laura , Strickland Sidney 
Published: December 2010

AbstractPeripheral nerve function depends on a regulated process of axon and Schwann cell development. Schwann cells interact with peripheral neurons to sort and ensheath individual axons. Ablation of laminin γ1 in the peripheral nervous system (PNS) arrests Schwann cell development prior to radial sorting of axons. Peripheral nerves of laminin‐deficient animals are disorganized and hypomyelinated. In this study, sciatic nerves of laminin‐deficient mice were treated with syngenic murine adipose‐derived stem cells (ADSCs). ADSCs expressed laminin in vitro and in vivo following transplant into mutant sciatic nerves. ADSC‐treatment of mutant nerves caused endogenous Schwann cells to differentiate past the point of developmental arrest to sort and myelinate axons. This was shown by (1) functional, (2) ultrastructural, and (3) immunohistochemical analysis. Treatment of laminin‐deficient nerves with either soluble laminin or the immortalized laminin‐expressing cell line 3T3/L1 did not overcome endogenous Schwann cell developmental arrest. In summary, these results indicate that (1) laminin‐deficient Schwann cells can be rescued, (2) a cell‐based approach is beneficial in comparison with soluble protein treatment, and (3) mesenchymal stem cells modify sciatic nerve function via trophic effects rather than transdifferentiation in this system. © 2010 Wiley‐Liss, Inc.
Mikrosynthese von 35S‐markiertem Aneurin hoher spezifischer Aktivität
Authors: Würsch J. 
Published: December 2010

AbstractAneurine‐35S of high specific activity has been prepared following an industrial procedure based on the synthesis of Todd & Bergel. Starting from 3,0 mmoles of H235S of the specific activity 40,3 mc/mmole, 216 mg of aneurine chloride hydrochloride monohydrate corresponding to a chemical yield of 40,5% based on H235S has been obtained. It was pure as shown by paper chromatography and had a calculated specific activity of 110 μc/mg or 39,1 mc/mmole immediately after synthesis.
Abbau von 3‐O‐Acetyl‐desarogenin und 3‐Dehydro‐11‐O‐acetyl‐sarmentogenin. Über Bestandteile der Nebennierenrinde und verwandte Stoffe, 97. Mitteilung
Authors: Lardon A. , Euw J. V. 
Published: December 2010

AbstractDie Überführung von 11‐Dehydro‐sarmentogenin in das bekannte 3β,21‐Diacetoxy‐5β‐pregnandion‐(11,20) und den bekannten 3β‐Acetoxy‐11‐keto‐5β‐ätiansäure‐methylester wird beschrieben, ferner die Überführung von 3‐De‐hydro‐sarmentogenin in den bekannten 11α‐Acetoxy‐3‐keto‐5β‐ätiansäure‐methylester. Die letztere Reaktionsfolge gab bisher unbefriedigende Ausbeuten.
Synthése de quelques aldéhydes p,p′‐polyméthylène‐dibenzoïques
Authors: Jaunin R. , Baer T. 
Published: December 2010

Abstractp,p′‐Polymethylene‐dibenzaldehydes (I, n = 6, 8, 9, 10) have been prepared by Kröhnke's method from the appropriate chloromethyl derivatives. Alternatively p,p′‐hexamethylene‐dibenzaldehyde (I, n = 6) has also been obtained by the LiAlH4 reduction of the corresponding bis‐(N‐methylanilide).
Reduktionen mit LiAlH4 in der Isatin‐Reihe. 3. Mitteilung. Zur Darstellung von N‐Methyl‐3‐hydroxy‐indolin
Authors: Giovannini E. , Lorenz Th. 
Published: December 2010

AbstractDie Reduktion von N‐Methylisatin (I), N‐Methyldioxindol (V), N‐Formylindoxyl (VI) und N‐Methyl‐β‐isatoxim (VII) mit LiAlH4 führte unter den angewandten Versuchsbedingungen jeweils zu N‐Methylindol (III) und den Leukoverbindungen von Farbstoffen der Indigoreihe, aber nicht zu N‐Methyl‐3‐hydroxy‐indolin (II); letzteres wurde durch direkte Methylierung von 3‐Hydroxy‐indolin dargestellt. Die Reduktion von N‐Formyl‐2,2‐dimethyl‐indoxyl (X) mit LiAlH4 führte zu N,2,2‐Trimethyl‐3‐hydroxy‐indolin (XI).
Syntheseversuche in der Emetin‐Reihe. 1. Mitteilung. 2‐Oxo‐hydrobenzo[a]chinolizine
Authors: Brossi A. , Lindlar H. , Walter M. , Schnider O. 
Published: December 2010

Abstract2‐Oxo‐1,2,3,4,6,7‐hexahydro‐11bH‐benzo[a]quinolizines unsubstituted in ring C (XXX, XXXI, XXXII, and XXXIII) and the homologues which are alkylated in 3‐position (V and analogues) were synthesized from 1‐carbalkoxy‐methyl‐1,2,3,4‐tetrahydro‐isoquinolines (VI, VII, VIII, and IX).
Zur Kenntnis der Pseudojononsynthese nach Kimel & Sax
Authors: Saucy G. , Chopard‐Dit‐Jean L. H. , Guex W. , Ryser G. , Isler O. 
Published: December 2010

AbstractIn the synthesis of pseudoionone by pyrolysis of dehydro‐linalyl‐acetoacetate (Kimel & Sax, US‐Pat. 2 661 368) an isomeric ketone is formed, the structure of which has been elucidated by degradation to d,l‐puleganic acid.
Voacangarin, ein neues Alkaloid aus Voacanga africana Stapf
Authors: Stauffacher D. , Seebeck E. 
Published: December 2010

AbstractAus Voacanga africana Stapf konnte ein neues Alkaloid, das Voacangarin, C22H28O4N2, isoliert werden. Es werden Abbaureaktionen beschrieben, welche beweisen, dass das Voacangarin ein Hydroxy‐carbomethyoxy‐ibogain ist, dem die Strukturformel I zukommt.
Sur la séparation des terres rares à l'aide de l'acide éthylènediamine‐tétraacétique. VI. Le système NH4[Gd‐édta]  NH4[Y‐édta]  H2O à 0°
Authors: Brunisholz G. , Randin M. 
Published: December 2010

AbstractTwo stable solid phases appear in the system NH4[Gd‐EDTA]  NH4[Y‐EDTA]  H2O at 0°C: the gadolinium‐rich octahydrate NH4[(Gd, Y)‐EDTA], 8H2O (= phase α) and the yttrium‐rich hexahydrate NH4[(Y, Gd)‐EDTA], 6H2O (= phase η). An important miscibility gap exists between the two phases.
Zur Kenntnis des Kohlenstoffringes. 75. Mitteilung. Über den nichtklassischen Verlauf der Acetolyse von Cyclodecyl‐[1‐D]‐p‐toluolsulfonat
Authors: Prelog V. , Borčić S. 
Published: December 2010

AbstractDas durch Acetolyse von Cyclodecyl‐[1‐D]‐p‐toluolsulfonat erhaltene trans‐Cyclodecen wurde systematisch bis zur Adipinsäure abgebaut und in den Abbau‐Produkten das Deuterium bestimmt. Die auf diese. Weise gefundene Deuterium‐Verteilung zeigt, dass ein beträchtlicher Teil der Eliminierung nichtklassisch, d.h. unter 1,5 bzw. 1,6‐Hydrid‐Verschiebung stattfindet.
Synthese der Racemate von Muscaron, Muscarin und epi‐Muscarin (Trennung der racemischen Muscarin‐Isomeren). 7. Mitteilung über Muscarin
Authors: Eugster C. H. , Häfliger F. , Denss R. , Girod E. 
Published: December 2010

AbstractDie Reduktion des 2‐Methyl‐5‐dimethylaminomethyl‐2,3‐dihydro‐furan‐3‐ons wurde unter verschiedenen Bedingungen untersucht. Aus den Reduktionsprodukten wurden die Norbasen von d,l‐Muscarin, d,l‐epi‐Muscarin und d,l‐Muscaron isoliert.
Untersuchungen der optischen Rotationsdispersion. XV. Anwendung auf Steroid‐Ketole und herzwirksame Aglykone. Glykoside und Aglykone, 186. Mitteilung
Authors: Djerassi C. , Halpern O. , Halpern V. , Schindler O. , Tamm Ch. 
Published: December 2010

Abstract
Mit Hilfe von optischen Rotationsdispersionskurven lassen sich bei Cardenolid‐Derivaten wie in andern Steroid‐Klassen zusätzliche Carbonylfunktionen ohne Schwierigkeiten erfassen. Bei den Bufadienolid‐Derivaten ist dies erst möglich, wenn der α‐Pyronring in hydrierter Form vorliegt.
Die Rotationsdispersionskurve von 1‐Keto‐steroiden zeigt einen aussergewöhnlichen Verlauf. Dies wird durch weitere entsprechende Cardenolid‐Derivate sowie durch Modellverbindungen illustriert.
Die Abhängigkeit der Rotationsdispersion von Cardenoliden mit einer α‐Ketol‐Gruppierung in 11,12‐Stellung sowohl von der Stereochemie dieser Gruppe selbst als auch von der des Ringgerüstes wird unter Heranziehung geeigneter Modelle (Ätiansäuren, Gallensäuren, Sapogenine) untersucht und diskutiert. Zum Vergleich wird die Rotationsdispersion einiger D‐Homo‐steroide mit einer α‐Ketol‐Gruppierung in 17α, 17a‐Stellung sowie weitere Steroid‐Derivate mit einer solchen in 4,5‐, 5,6‐, 16,17‐ und 17,20‐Stellung bestimmt und diskutiert.
Programmgesteuerter Gas‐Chromatograph zur präparativen Trennung von Gemischen organischer Verbindungen. Teil II
Authors: Kováts E. , Simon W. , Heilbronner E. 
Published: December 2010

AbstractThe following characteristics of the automatic gas chromatograph for preparative purposes previously described have been investigated : (a) the dependance of the separation efficiency on temperature, type of stationary phase, retention volume, flow rate of the carrier gas and amount of sample and the conditions prevailing during preparative gas chromatography, (b) the separation of two component mixtures with and without overlapping peaks in their gas chromatogram.
Umwandlung von Cardenoliden durch Mikroorganismen: I. 12β‐Hydroxylierung von Digitoxigenin. 1. Mitteilung über Reaktionen mit Mikroorganismen
Authors: Gubler Alice , Tamm Ch. 
Published: December 2010

AbstractDigitoxigenin (I) wurde auf mikrobiologischem Wege (mit Fusarium Zini (Bolley)) durch Einführung einer Hydroxylgruppe in die 12β‐Stellung in Digoxigenin (VII) übergeführt. Der gleiche Mikroorganismus vermochte 3‐De‐hydro‐digitoxigenin (X) in 3‐epi‐Digitoxigenin (XII), 3‐Dehydro‐digoxigenin (XI) und 3‐epi‐Digoxigenin (XIV) umzuwandeln. XI und XIV sind neue Stoffe. Zum Konstitutionsbeweis wurde XI durch katalytische Oxydation mit O2, und Pt aus Digoxigenin (VII) hergestellt. NaBH4,‐Reduktion von XI ergab 3‐epi‐Digoxigenin (XIV).
Bathochromic displacements and other steric effects in electronic spectra
Authors: Forbes W. F. 
Published: December 2010

AbstractA recently proposed unified theory of steric effects in the electronic spectra of organic compounds is criticised on the grounds that steric effects of that type normally fall into at least two distinct patterns. It is proposed that these two types of steric effects can be better understood by being treated independently. A brief survey of the relevant data is given.
Zur Kenntnis der Sulfen‐ und Selenensäuren und ihrer Derivate. 6. Mitteilung. Synthese von Anthrachinon‐1,5‐disulfensäure
Authors: Jenny W. 
Published: December 2010

AbstractDie Synthese einer zweiten analysenreinen, beständigen Sulfensäure, der Anthrachinon‐1,5‐disulfensäure, wird beschrieben. Die optischen Eigenschaften des Anions dieser Säure werden untersucht.
Infrarot‐Spektren von Cyclanen und Cyclanonen. IV. Infrarot‐Spektren von Cyclanen
Authors: Billeter E. , Günthard Hs. H. 
Published: December 2010

AbstractThe infrared spectra of the n‐membered cyclanes (n = 10, 12, 13, 14, 15, 16, 17, 18) have been investigated over the frequency range 1600 to 650 cm−1 at temperatures between − 180° and + 100° C in liquid and solid state and for comparison in solid state pressed in KBr. Furthermore the spectra of the liquids at temperatures about 20° C above the melting points and those of thin crystalline films have been observed in the rocksalt region.
Synthese des d,l‐7‐Methyltocols (η‐Tocopherol)
Authors: Pendse H. K. , Karrer P. 
Published: December 2010

AbstractAus Methylhydrochinon, Phytol und Ameisensäure als Kondensationsmittel wurde ein Monomethyltocol hergestellt, aus dem sich ein gut kristallisiertes Allophanat und ein ebenfalls gut kristallisiertes p‐Nitrophenylurethan darstellen liessen. Beim thermischen Abbau gab dieses Methyltocol 2,5‐Dimethylhydrochinon, wodurch bewiesen wird, dass es sich um 7‐Methyltocol handelt. Damit in Übereinstimmung steht sein Verhalten bei der Nitrosierung und Kupplung mit diazotiertem o‐Dianisidin.
Nitration de l'acide nitro‐2‐bromo‐4‐benzoïque
Authors: Goldstein Henri , Mohanna Siavache 
Published: December 2010

AbstractLa nitration de l'acide nitro‐2‐bromo‐4‐benzoïque conduit à l'acide dinitro‐2,5‐bromo‐4‐benzoïque avec formation secondaire d'isomère 2,3.
Lanatosid E, ein neues genuines Glykosid aus der Digitalis lanata Ehrh. 40. Mitteilung über Herzglykoside
Authors: Angliker E. , Barfuss F. , Renz J. 
Published: December 2010

AbstractAus Herzglykosidfraktionen der Digitalis lanata Ehrh. konnte das Lanatosid E isoliert und charakterisiert werden. Durch verschiedene Abbaureaktionen konnte gezeigt werden, dass das mit den bekannten Lanatosiden isomorph kristallisierende Glykosid das 16‐Formyl‐lanatosid B darstellt.