bluuebunny/crossref_metadata_2025_split huggingface dataset:
Targeting murine small bowel and colon through selective superior mesenteric artery injection
Authors: Porvasnik Stacy L. , Mah Cathryn , Polyak Steven 
Published: March 2010

AbstractAdministration of molecular, pharmacologic, or cellular constructs to the intestinal epithelium is limited by luminal surface mucosal barriers and ineffective intestinal delivery via systemic injection. Many murine models of intestinal disease are used in laboratory investigation today and would benefit specific modulation of the intestinal epithelium. Our aim was to determine the feasibility of a modified microsurgical approach to inject the superior mesenteric artery (SMA) and access the intestinal epithelium. We report the detailed techniques for selective injection of the SMA in a mouse. Mice were injected with methylene blue dye to grossly assess vascular distribution, fluorescent microspheres to assess biodistribution and viral vector to determine biological applicability. The procedure yielded good recovery with minimal morbidity. Tissue analysis revealed good uptake in the small intestine and colon. Biodistribution analysis demonstrated some escape from the intestine with accumulation mainly in the liver. This microsurgical procedure provides an effective and efficient method for delivery of agents to the small intestine and colon, including biological agents. © 2010 Wiley‐Liss, Inc. Microsurgery 30:487–493, 2010.
Use of rat segmental intestine for fetal pancreatic transplantation
Authors: Iwasaki Junji , Hata Toshiyuki , Hishikawa Shuji , Fujimoto Yasuhiro , Uemoto Shinji , Murakami Takashi , Kobayashi Eiji 
Published: March 2010

AbstractIt is thought that the small intestine may provide a scaffold for pancreas regeneration. Herein, we investigated whether fetal pancreatic tissue could be transplanted into the segmental intestine in rats. Fetal pancreases from firefly luciferase transgenic Lewis rat embryos (embryonic day 14.5 and 15.5) were transplanted into streptozotocin (STZ)‐induced diabetic wild‐type Lewis rats. As a scaffold for pancreatic development, rat small intestinal segments were utilized after the removal of mucosa, and fetal pancreases were grafted into the luminal surface through the stoma. We also transplanted fetal pancreases into the omentum. The survival of transplanted fetal pancreases was monitored by luciferase‐derived photons and blood glucose levels. Transplanted fetal pancreas‐derived photons were stable for 28 days, suggesting that transplanted fetal pancreatic tissues survived and that their intestinal blood supply was maintained. © 2010 Wiley‐Liss, Inc. Microsurgery, 2010.
Compact dual‐wideband antenna for WLAN/WiMAX applications
Authors: Ye Liang‐Hua , Chu Qing‐Xin 
Published: March 2010

AbstractA compact CPW‐fed dual‐wideband antenna formed by a rectangular ring monopole and a rectangular monopole is presented. The measured 10 dB bandwidths for return loss are achieved to be 46.3% (2.36–3.78 GHz) and 31.4% (5.1–7 GHz) in the lower and upper band, respectively, covering all the 2.4/5.2/5.8 GHz WLAN bands and the 2.5/3.5/5.5 GHz WiMAX bands. Further, the proposed antenna has a simple planar structure and occupies a small size of 28 × 36 mm2, including the finite ground CPW feeding mechanism. Good monopole‐like radiation characteristic are obtained over the operating bands. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1228–1231, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25156
Compact quad‐band antenna based on zeroth‐order resonator for mobile handset applications
Authors: Ji Jeong Keun , Kim Gi Ho , Seong Won Mo 
Published: March 2010

AbstractA compact quad‐band antenna using zeroth‐order resonator (ZOR) for GSM850, DCS1800, PCS1900, and UMTS operations are presented. The proposed antenna comprises a lower band ZOR portion and an upper band ZOR portion. The zeroth‐order resonant properties are analyzed by amplitude and phase distributions of the surface magnetic field using near‐field scanning system. The performance of the antenna is verified by experimental data obtained from fabrication and measurement. The antenna offers omnidirectional radiation patterns and measured radiation efficiencies exceeding about 51% and 43% for lower and upper bands, respectively. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1298–1301, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25160
Ka‐band substrate integrated waveguide voltage‐controlled Gunn oscillator
Authors: Cao Zhou , Tang Xiaohong , Qian Kewei 
Published: March 2010

AbstractA Ka‐band substrate integrated waveguide (SIW) voltage‐controlled oscillator (VCO) is demonstrated using GaAs Gunn diode.GaAs hyperabrupt varactor is employed in parallel to the Gunn diode for low phase noise and wideband tuning. The VCO achieves a tuning range of more than 1 GHz by varying the varactor tuning voltage between 0 V and 9 V, and phase noise of −102.1 dBc/Hz at 1 MHz offset from a 36 GHz carrier frequency. The output power varies from 9.3 dBm to 11.3 dBm within the tuning range. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1232–1235, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25169
Micromachined air‐filled patch antennas for millimeter‐wave applications
Authors: Wang Yi , Ke Maolong , Lancaster Michael J. 
Published: March 2010

AbstractAir‐filled patch antennas for millimeter‐wave (mm‐wave) applications are demonstrated using silicon‐based micromachining techniques. The antennas are fed by rectangular coaxial lines and made of five gold plated layers bonded together. Each layer is made by deep reactive etching on silicon. The patches are suspended by stubs, without using any dielectric materials. The dielectric free structure not only avoids dielectric losses but also eliminates spurious surface modes that often trouble substrate supported patch antennas at mm‐wave frequencies. The predicted gain of the patch is as high as 9.4 dBi with a patch dimension of 3.27 mm by 3.54 mm at 38 GHz. A radiation pattern measurement has been performed and results shown. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1345–1347, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25183
Analysis of tunable flat dispersion of germanium doped fiber with liquid cladding
Authors: Liu Y. , Chen N. , Lai Y. , Chi S. 
Published: March 2010

AbstractWe demonstrate numerically the tunable dispersion‐flattened fibers can be achieved by immersing the Ge‐doped fiber core in different liquid claddings.The dispersion slope can be flattened over 1100–1700 nm, which is suitable for tunable supercontinuum generation with pumping wavelength in fiber communication or other wavelength regions. Finally, we demonstrate the feasibility to fabricate the proposed structure with chemical etching method. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1357–1359, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25209
Multi‐band chip antenna for WiMAX applications
Authors: Lin Shun‐Yun , Ke Bi‐Jin 
Published: March 2010

AbstractA novel chip antenna for dual‐/tri‐band operation is presented in this article.The design consists of a pair of forked metal strips with different lengths. The longer strip is folded onto an FR4 base to simultaneously introduce the quarter‐ and half‐wavelength modes as the first two operating bands. By varying the included angle between the sections of strip on the opposite base layers, the frequency ratio of the first two operating modes is adjusted over a large range of 1.34–2.29. In addition, the shorter excited strip introduces the quarter‐wavelength mode as the third operating band. The tri‐band operation with a small dimension of 13 × 5 × 0.8 mm3for 2.5/3.5/5.5 GHz WiMAX applications is implemented. Experimental results show that the proposed antenna has good omnidirectional radiation patterns and steady antenna gains over all operating bands. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1286–1290, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25211
On the numerical resolution of the discontinuous material bifurcation problem
Authors: Oliver J. , Huespe A. E. , Cante J. C. , Díaz G. 
Published: March 2010

AbstractThe work focuses on the numerical resolution of the discontinuous material bifurcation problem as a relevant ingredient in computational material failure mechanics. The problem consists of finding the conditions for the strain localization onset in terms of the so‐called bifurcation time, localization directions and localization modes. A numerical algorithm, based on the iterative resolution of a coupled eigenvalue problem in terms of the localization tensor, is proposed for such purpose. The algorithm is shown to be always convergent to the exact solution for the symmetric case (major and minor symmetries of the tangent constitutive operator). In the unsymmetric case (only minor symmetries), the solution is no longer exact, although it is shown that using the symmetric part of the localization tensor in the proposed algorithms provides enough accurate solutions for most of cases. Numerical examples illustrate the benefits of the proposed methodology in terms of accuracy and savings in the computational cost associated with the problem. Copyright © 2010 John Wiley & Sons, Ltd.
Upfront use of gemtuzumab ozogamicin in young children with CD33‐positive AML
Authors: Sayar Dror , Burstein Yoav , Bielorai Bela , Toren Amos , Dvir Rina 
Published: March 2010

AbstractGemtuzumab ozogamicin (GO) is a humanized anti‐CD33 antibody used for treating patients with CD33+ acute myeloid leukemia (AML). We report three young children (two infants and one toddler) with AML treated with GO 9 mg/m2. Two received two doses at diagnosis alone with conventional chemotherapy and one received one dose after relapse. GO was well tolerated and all three achieved remission. All were transplanted: one relapsed after 5 months and died of disease, one died a toxic death in remission due to pulmonary fibrosis, and one survived (41 months from diagnosis). In conclusion, GO was well tolerated in these young patients with evidence for efficacy. Pediatr Blood Cancer 2010;55:183–185. © 2010 Wiley‐Liss, Inc.
A new methodology to preserve the original proportion and integrity of cell‐free fetal DNA in maternal plasma during sample processing and storage
Authors: Fernando M. R. , Chen K. , Norton S. , Krzyzanowski G. , Bourne D. , Hunsley B. , Ryan W. L. , Bassett C. 
Published: March 2010

AbstractObjectiveTo develop a standardized blood collection device that preserves fetal cell‐free DNA and minimizes the cell‐free DNA background in maternal plasma.MethodsBlood samples were drawn from healthy pregnant donors into K3EDTA (BD vacutainer®) and Cell‐free DNA™ BCT tubes (Streck®, Inc.) and kept at ambient temperature. Plasma was separated by centrifugation and cell‐free DNA was extracted. Cell‐free DNA from plasma was quantified by quantitative real‐time polymerase chain reaction.ResultsBlood drawn into Cell‐free DNA™ BCT tubes showed no change in the original proportion of fetal cell‐free DNA during a 14‐day storage period at ambient temperature. Conversely, maternal blood drawn into K3EDTA tubes showed a steady reduction in the original proportion of fetal cell‐free DNA over the same time period. Using maternal plasma stored in Cell‐free DNA™ BCT tubes for 14 days, fetal cell‐free DNA was amplified 80‐fold using whole genome amplification (WGA).ConclusionUsing Streck's Cell‐free DNA™ BCT tubes, it is possible to preserve the original proportion of fetal cell‐free DNA for extended times as well as minimize the post‐sampling maternal cell‐free DNA background. Preserved in this way, fetal cell‐free DNA can be amplified by WGA technology to be used in prenatal diagnostic tests. Copyright © 2010 John Wiley & Sons, Ltd.
Orthogonal predictions: follow‐up questions for suggestive data
Authors: Walker Alexander M. 
Published: March 2010

AbstractWhen a biological hypothesis of causal effect can be inferred, the hypothesis can sometimes be tested in the selfsame database that gave rise to the study data from which the hypothesis grew. Valid testing happens when the inferred biological hypothesis has scientific implications that predict new relations between observations already recorded. Testing for the existence of the new relations is a valid assessment of the biological hypothesis, so long as the newly predicted relations are not a logical correlate of the observations that stimulated the hypothesis in the first place. These predictions that lead to valid tests might be called ‘orthogonal’ predictions in the data, and stand in marked contrast to ‘scrawny’ hypotheses with no biological content, which predict simply that the same data relations will be seen in a new database. The Universal Data Warehouse will shortly render moot searches for new databases in which to test. Copyright © 2010 John Wiley & Sons, Ltd.
Validating injection stretch‐blow molding simulation through free blow trials
Authors: Menary G.H. , Tan C.W. , Armstrong C.G. , Salomeia Y. , Picard M. , Billon N. , Harkin‐Jones E.M.A. 
Published: March 2010

AbstractA 2D isothermal finite element simulation of the injection stretch‐blow molding (ISBM) process for polyethylene terephthalate (PET) containers has been developed through the commercial finite element package ABAQUS/standard. In this work, the blowing air to inflate the PET preform was modeled through two different approaches: a direct pressure input (as measured in the blowing machine) and a constant mass flow rate input (based on a pressure–volume–time relationship). The results from these two approaches were validated against free blow and free stretch‐blow experiments, which were instrumented and monitored through high‐speed video. Results show that simulation using a constant mass flow rate approach gave a better prediction of volume vs. time curve and preform shape evolution when compared with the direct pressure approach and hence is more appropriate in modeling the preblowing stage in the injection stretch‐blow molding process. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers
Compatibilization of PP/PAE blends by means of the addition of an ionomer
Authors: Granado A. , Eguiazábal J.I. , Nazábal J. 
Published: March 2010

AbstractMinor amounts of poly(ethylene‐co‐methacrylic acid) ionomer neutralized with Zn (PEMA‐Zn) were added in the melt state to blends of polypropylene (PP) with up to 40% of poly(amino ether) (PAE) resin. Given the good barrier characteristics of PAE, it is a good candidate to improve the poor barrier properties of PP. However, PP/PAE blends were found to be almost fully immiscible, with a large dispersed phase size and a brittle mechanical behavior. Upon PEMA‐Zn addition, the dispersed particle size clearly decreased from diameters of several microns to diameters mostly below 0.5 μm, indicating that compatibilization occurred. This compatibilization was due to the presence of PEMA‐Zn in the two phases of the blends and was additionally proven by the large decrease observed in the interfacial tension. Further, the fine morphology led to an enhancement in the unnotched impact strength of the ternary blends and of their ductile behavior (elongation at break 30‐ to 40‐fold that of the corresponding binary blends). POLYM. ENG. SCI., 50:1512–1519, 2010. © 2010 Society of Plastics Engineers
Pyrolysis of hyperbranched polyborate modified phenolic resin
Authors: Xu Peijun , Jing Xinli 
Published: March 2010

AbstractHyperbranched polyborate (HBPB) is a new polymer with highly branched structures, plenty of functional end groups and excellent thermal resistance, which can be used as a positive modifier for phenolic resin (PR) to greatly increase the carbon yield of PR. In the present article, thermal properties and structural changes of HBPB modified PR (PR‐HBPB) during the pyrolysis are studied. The pyrolysis mechanism of PR‐HBPB is proposed to explain the increase of the carbon yield of PR‐HBPB. It is found that the carbon yields of PR‐HBPBs containing 10 and 20 wt% of HBPB are 71.3 and 73.1% at 800°C in nitrogen, which are higher than those of PR and HBPB but not the sum of the carbon yields of PR and HBPB in consideration of their mixing ratio. The increase of carbon yield of PR‐HBPB can be attributed to the combined effects of the excellent thermal stability of HBPB, the formation of BC3 and B2O3, promoted graphitization by HBPB and the protection of B2O3 on the edges of the graphite microcrystallites. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers
Influence of molecular parameters on thermal, mechanical, and dynamic mechanical properties of hydrogenated nitrile rubber and its nanocomposites
Authors: Choudhury Anusuya , Bhowmick Anil K. , Ong Christopher , Soddemann Matthias 
Published: March 2010

AbstractThe present work derives a relationship between structure and properties of hydrogenated nitrile rubber (HNBR) in the presence as well as absence of nanofillers. Four different grades of HNBR were selected to examine the influence of polarity, unsaturation, and molecular weight on thermal, mechanical, and dynamic mechanical properties of the elastomers and particularly their nanocomposites. An increase in thermal stability, tensile strength, modulus at 100% elongation as well as storage modulus of the unfilled rubber was observed with increase in polarity (acrylonitrile content). Different nanofillers, such as montmorillonite, sepiolite, and nanosilica were used to improve the above properties of the unfilled rubber. Interestingly, a reverse trend of thermal properties was observed for the nanocomposites with acrylonitrile variation, although mechanical and dynamic mechanical properties exhibited similar trend to those of the unfilled rubber. These properties, however, gradually deteriorated as the level of unsaturation on the polymer backbone was increased. On addition of the nanofillers, it was found that the improvement in thermal and mechanical properties was higher for the elastomer having 5.5% diene content. The results were explained by X‐ray Diffraction, Atomic Force Microscopy, Energy Dispersive X‐ray mapping, and swelling studies. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers
Wear properties of 3‐aminopropyltriethoxysilane‐functionalized carbon nanotubes reinforced ultra high molecular weight polyethylene nanocomposites
Authors: Lee Ji‐Hoon , Kathi John , Rhee Kyong Yop , Lee Joong Hee 
Published: March 2010

AbstractUltra high molecular weight polyethylene (UHMWPE) is extensively used as a material in various high‐end applications with superior mechanical properties. Carbon nanotubes (CNTs) reinforced UHMWPE (CNT/UHMWPE) nanocomposite is a promising material that can compensate for the weak durability of UHMWPE. In this study, multiwalled carbon nanotubes were oxidized and silanized using acid mixture and 3‐aminopropyltriethoxysilane, respectively, to improve the interfacial strength between CNTs and UHMWPE. The CNT/UHMWPE nanocomposite was fabricated using these oxidized and silanized CNTs. The treatment effect of CNTs on the wear behavior of the CNT/UHMWPE nanocomposites was investigated through wear tests. The oxidization and silanization of CNTs were confirmed by infrared spectroscopy. Scanning electron microscope analysis showed that the silane‐treated CNT/UHMWPE nanocomposites showed better dispersion and interfacial adhesion between UHMWPE and CNTs becaue of the newly formed functional groups on the CNTs. The friction coefficient and wear rate of silanized CNT/UHMWPE nanocomposite were also found to be lower than those of raw UHMWPE and oxidized CNT/UHMWPE nanocomposite. CNTs were functionalized using oxidation and silanization methods to improve the interfacial adhesion between CNTs and UHMWPE. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers
Reinforcement of liquid ethylene–propylene–dicyclopentadiene copolymer based elastomer with vinyl functionalized multiwalled carbon nanotubes
Authors: Zhou Hongfu , Zhang Chen , Li Hangquan , Du Zhongjie , Li Congju 
Published: March 2010

AbstractA methodology for reinforcement of liquid ethylene–propylene–dicyclopentadiene copolymer (liquid‐EPDM) based elastomer with multiwalled carbon nanotubes (MWCNTs) was proposed. Acid‐treated MWCNTs were first reacted with poly(acryloyl chloride) (PACl) leading to a grafted encapsulation, which were subsequently reacted with hydroxy ethyl acrylate (HEA) to generate vinyl groups. Thus obtained vinyl groups functionalized MWCNTs (vinyl‐MWCNTs) were characterized using Fourier transform infrared spectroscopy, transmission electron microscopy, and thermogravimetric analysis. The vinyl‐MWCNTs were blended with liquid‐EPDM and subjected to co‐curing; an intercrosslinked structure was obtained via the free radical polymerization among the vinyl groups on vinyl‐MWCNTs and the double bonds on liquid‐EPDM. As a result, the vinyl‐MWCNTs and the cured EPDM matrix were covalently linked. The chemical interfacial interaction between vinyl‐MWCNTs and the cured matrix were observed by scanning electron microscope, which provided obvious reinforcement of elastomer. POLYM. ENG. SCI., 2010. © 2010 Society of Plastics Engineers
Three‐dimensional scanning electron microscopy characterization of the topography of textured polymeric surfaces
Authors: Ignell Sofie , Ariño Ruth , Iannuzzi Giovanna , Kleist Ulf , Rigdahl Mikael 
Published: March 2010

AbstractA stereographic scanning electron microscopy (SEM) technique combined with a filtering procedure was used to characterize the surface topography of injection‐molded polymeric plaques to improve the understanding of the relation between surface texture and gloss of deliberately textured and quite rough surfaces. The specimens, having small differences in surface topography and gloss, were produced by using two mold cavities with slight differences in surface texture and three different polymers. Small differences in gloss were also achieved by changing the processing conditions. All specimens exhibited a very low gloss. A stereographic image of the textured surface was constructed from two SEM micrographs of the same area, but differing slightly in viewing angle. From this image, descriptors characterizing the surface topography could be evaluated, in the present study the root‐mean‐square roughness and a lateral correlation length. The results indicated that small differences in gloss in the low gloss region could to a significant extent be associated with small‐scale variations in the surface topography. The SEM method used might provide a useful tool for identifying the length scale at which the surface pattern or irregularities has a strong effect on the appearance of polymeric low‐gloss surfaces. POLYM. ENG. SCI., 50:1527–1534, 2010. © 2010 Society of Plastics Engineers