bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viral-mediated inflammation by Poly I:C induces the chemokine CCL5 in NK cells and its receptors CCR1 and CCR5 in microglia in the neonatal rat cerebellum
Authors: Perez-Pouchoulen Miguel , Holley Amanda S. , Reinl Erin L. , VanRyzin Jonathan W. , Mehrabani Amir , Dionisos Christie , Mirza Muhammed , McCarthy Margaret M. 
Published: April 2024

Abstract

Objectives
To study the effect of viral inflammation induced by Polyinosinic:polycytidylic acid (PIC) on the cerebellum during a critical period of development in rats.

Methods
Neonatal rat pups were treated with PIC on postnatal days (PN) 8 and 10 after which we quantified RNA using Nanostring, qRT-PCR and RNAscope and analyzed immune cells through flow cytometry and immunohistochemistry on PN11. Using the same paradigm, we also analyzed play juvenile behavior, anxiety-like behavior, motor balance using the balance beam and the rotarod assays as well as fine motor behavior using the sunflower seed opening test.

Results
We determined that male and female pups treated with PIC reacted with a significant increase in CCL5, a chemotactic cytokine that attracts T-cells, eosinophils and basophils to the site of inflammation, at PN11. PIC treatment also increased the expression of two receptors for CCL5, CCR1 and CCR5 in the cerebellar vermis in both males and females at PN11. In-situ hybridization (RNAscope®) for specific transcripts revealed that microglia express both CCL5 receptors under inflammatory and non-inflammatory conditions in both males and females. PIC treatment also increased the total number of CCL5+ cells in the developing cerebellum which were determined to be both natural killer cells and T-cells. There were modest but significant impacts of PIC treatment on large and fine motor skills and juvenile play behavior.

Conclusions
Our findings suggest an important role for CCL5 and other immune cells in mediating inflammation in the developing cerebellum that potentially impact the maturation of cerebellar neurons during a critical period of development.
La fermeture des établissements scolaires en temps de pandémie : point de vue d’adolescents et d’adolescentes en région éloignée sur les changements perçus dans leur pratique d’activité physique
Authors: Guay Sandrine , Pouliot Eve , Maltais Danielle , Giroux Patrick , Simard Ann-Sophie , Maltais-Dufour Olivia , Lacelle Catherine 
Published: April 2024

En raison de la pandémie, en mars 2020, les adolescents et les adolescentes se sont retrouvés confinés à leur domicile pour un temps indéterminé. Afin de mieux comprendre leur vécu dans ce contexte particulier, notamment en ce qui concerne leurs habitudes de vie, des entrevues de groupe (n=10) ont été réalisées auprès de 57 jeunes fréquentant trois écoles secondaires du Saguenay-Lac-Saint-Jean en 2021-2022. Les résultats soulignent la pertinence de mieux comprendre leur vécu et leurs besoins en temps de crise, de même que l’importance du rôle des milieux scolaires quant à la pratique d’activité physique chez les jeunes, et ce, en vue d’améliorer la qualité du soutien qui leur est offert.
Factors Impact of the Stock Market Performance During the Covid-19 Crisis
Authors: Goh Thomas Sumarsan , Henry Henry , Erika Erika 
Published: April 2024

Research originality: This research adds the exchange rate variable and the use of the Vector Autoregressive (VAR) model that can add to the financial literature.Research Objectives: This study examines how macroeconomics can impact a business during a crisis. The stock market has associated access with new COVID-19 cases and new deaths in Indonesia. During the pandemic, the exchange rate is critical, so this study observes the exchange rate of IDR against USD. This paper investigates the relationship between new cases, new deaths, and the exchange rate with the stock market index.Research Methods: The study retrieves the daily data from March 2, 2020, to June 30, 2022, from Our World in Data, Indonesia's stock exchange, and Indonesia's Statistic Central Bureau. We have used the ADF, Vector Autoregressive (VAR) Model, impulse response function, and the Toda Yamamoto causality test. Empirical Results: The findings reveal a significant negative impact of new COVID-19 cases, new deaths, and exchange rates on the stock market. Toda Yamamoto's causality analysis reveals substantial evidence of unidirectional daily growth of new COVID-19 deaths in the stock market and a bidirectional causality of new COVID-19 cases and new COVID-19 deaths.Implications: The policy implications of this study are to stabilize markets, impact overall financial stability, support entrepreneurship, and develop a competitive market environment that can encourage innovation. JEL Classification: C5, E31, F31How to Cite:Goh, T. S., Henry, H., & Erika, E. (2024). Factors Impact of the Stock Market Performance During the Covid-19 Crisis. Etikonomi, 23(1), 47 – 62. https://doi.org/10.15408/etk.v23i1.32005
Islamic and Conventional Banks Stability in Indonesia
Authors: Khan Shabeer , Aziza Nur Amalia , Nawaz Allah Ditta 
Published: April 2024

Research Originality: The stability of banking institutions is crucial for the overall financial health of a country. The originality of this paper lies in its innovative use of quantile regression analysis to provide a nuanced understanding of the factors influencing bank stability, particularly in the Indonesian context.Research Objectives: This research identifies factors influencing bank stability in Islamic and conventional banks in Indonesia.Research Methods: Utilizing quantile regression analysis to measure the impact of various factors at different quantiles, addressing the existing mixed findings in the literature. This study utilizes 15 years of data, encompassing 61 observations for Islamic banks and 779 observations for conventional banks in Indonesia.Empirical Results: The study identifies impaired loans as the primary determinant of bank stability in Indonesia, with a notably greater impact on conventional banks compared to Islamic banks. Notably, the upper quantile of Islamic banks indicates a decline or a lesser impact on bank stability. The paper additionally concludes that the stability of Islamic banks in Indonesia is comparatively lower than conventional banks.Implications: By offering insights into the different levels of factors affecting bank stability, the study contributes to the existing literature, sheds light on unique dynamics, and highlights potential recommendations for enhancing bank stability, especially in the context of non-performing loans.JEL Classification: C21, C23, G21How to Cite:Khan, S., Aziza, N. A., & Nawaz, A. D. (2024). Islamic and Conventional Banks Stability in Indonesia. Etikonomi, 23(1), 167 – 182. https://doi.org/10.15408/etk.v23i1.33879.
Measuring Procyclicality Behavior on Islamic and Conventional Banks in Indonesia
Authors: Wiranatakusuma Dimas Bagus , Muttaqin Ecky Imamul 
Published: April 2024

Research Originality: This study contributes to capturing credit cycle movements during the COVID-19 pandemic and compares sizes of credit and business cycles to promote banking stability.Research Objectives: This study attempts to examine banking behavior on amplitude and frequency indicators by focusing on the credit property of Islamic and conventional banks from 2014 to 2020.Research Methods: Ordinary Least Square, frequency base filter and turning point analysis are used.Empirical Results: This study unveiled that the size of an Islamic bank’s amplitude was higher than conventional bank’s amplitude. Meanwhile, the size of the frequency of Islamic banks had a longer frequency than conventional banks, given Islamic banks rely on real sector-based financing which has a longer period of economic expansion.Implications: It is also argued that conventional banks have a riskier leverage indicated by a higher percentage of amplitude. Thus, it is recommended to Indonesian banking sectors to promote the growth of Islamic banks to achieve financial stability. This research is significance in showing the Islamic banking’s contribution on stability given Indonesia is taking serious effort becoming the epicentrum of Islamic finance growth in the world.JEL Classification: E51, G01, G21How to Cite:Wiranatakusuma, D. B., & Muttaqin, E. I. (2024). Measuring Procyclicality Behavior on Islamic and Conventional Banks in Indonesia. Etikonomi, 23(1), 249 – 270. https://doi.org/10.15408/etk.v23i1.35293.
Preference Digital Wallet by Generation Z with the Unified Theory of Acceptance and Use of Technology 2 (UTAUT 2) Model Approach and Perceived Risk
Authors: Elasaria Rani , Nurabiah  
Published: April 2024

Purpose: This empirical study explores the use of digital wallets by Gen Z in Indonesia. This study uses a quantitative approach and collects data through distributing questionnaires to respondents online. The instrument in the questionnaire includes questions related to the effect of performance expectancy, effort expectancy, social influence, facilitating conditions, hedonic motivation, price value, habit, and perceived risk on behavioral intention, habit and behavioral intention on use behavior, and perceived risk on financial risk, performance risk, and privacy risk.
Design/Method/Approach: This research uses primary data with a sample of generation Z in Indonesia as digital wallet users. The total observations amounted to 742 respondents, and used quantitative methods with PLS-SEM statistical analysis tools to test the hypothesis.
Findings: This research shows that the variables of behavioral Intention and habit have a significant effect on use behavior, the variables of hedonic motivation, habit, and perceived risk have a significant effect on behavioral intention, the variable perceived risk has a significant effect on financial risk, performance risk and privacy risk in using digital wallets.
Theoretical Implications: This research provides empirical evidence for theory development, as it contributes to empirically applying the UTAUT 2 model as a theoretical framework and applying the concept of risk perception as a complement to the theoretical model, to analyze the factors that influence digital wallet adoption.
Practical Implications: Practically, this research provide precious knowledge for digital wallet managers. Digital wallet managers are supposed to develop features that can provide additional convenience for digital wallet usage, and can take concrete measures to address the risks encountered by users.
Originality/Value: The first research to explore digital wallet preferences with the UTAUT 2 model approach and perceived risk. This paper provides valuable knowledge for researchers interested in understanding digital wallet usage intentions.
Research Limitations/Future Research: Future research is expected to involve multiple countries to contribute to a deeper understanding, and may consider using multiple technology measurement models simultaneously.
Paper Type: Empirical
JEL Classification: C12, E42, F65, G41
Tales in Athenaeus of divine statues preventing or favoring journeys
Authors: Di Serio Chiara 
Published: April 2024

AbstractThis article focuses on two stories contained in Deipnosophists 15 by Athenaeus of Naucratis. Both stories are comprised in the section in which Athenaeus discusses the use of crowns in festive rituals. Athenaeus attributes the first story (672a–e) to Menodotus of Samos. Here we read that some Tyrrhenians went to Samos to steal the simulacrum of Hera. But, having boarded the ship with the statue, they were unable to set sail. Thus, they unloaded the simulacrum on the shore and left. Then the heroine Admete retrieved it and took it back to the temple. For this reason, every year since then, the inhabitants of Samos celebrated the feasts called Tonaia in honor of Hera. The second story, that Athenaeus draws from Polycarmus of Naucratis (675f–676b), tells of a certain Herostratus who, on his return journey from Cyprus to Naucratis, was saved from a storm thanks to the sailors' prayers to the statue of Aphrodite on board. Thereafter, Herostratus prepared a banquet at the temple of the goddess to honor her. These stories introduce the recurring motif, also found in other sources, of travelling divine statues, which display supernatural powers.
Hydrogen in energy and information sciences
Authors: Chung Heejung W. , Cladek Bernadette , Hsiau Yong-Yun , Hu Yan-Yan , Page Katharine , Perry Nicola H. , Yildiz Bilge , Haile Sossina M. 
Published: April 2024

AbstractBeyond its fascinating chemistry as the first element in the Periodic Table, hydrogen is of high societal importance in energy technologies and of growing importance in energy-efficient computing. In energy, hydrogen has reemerged as a potential solution to long-term energy storage and as a carbon-free input for materials manufacturing. Its utilization and production rely on the availability of proton-conducting electrolytes and mixed proton–electron conductors for the components in fuel cells and electrolyzers. In computing, proton mediation of electronic properties has garnered attention for electrochemically controlled energy-efficient neuromorphic computing. Incorporation of substitutional and interstitial hydride ions in oxides, though only recently established, enables tuning of electronic and magnetic properties, inviting a range of possible exotic applications. This article addresses common themes in the fundamental science of hydrogen incorporation and transport in oxides as relevant to pressing technological needs. The content covers (1) lattice (or bulk) mechanisms of hydrogen transport, primarily addressing proton transport, but also touching on hydride ion transport; (2) interfacial transport; (3) exploitation of extreme external drivers to achieve unusual response; and (4) advances in methods to probe the hydrogen environment and transport pathway. The snapshot of research activities in the field of hydrogen-laden materials described here underscores exciting recent breakthroughs, remaining open questions, and breathtaking experimental tools now available for unveiling the nature of hydrogen in solid-state matter.
Graphical abstract
Cytokine profile of nasal polyps and clinical characteristics of patients with polypous rhinosinisitis at different degree of therapeutic control and disease severity
Authors: Savlevich E. L. , Lyubimova E. V. , Zurochka A. V. , Mitrofanova E. S. , Shilovskiy I. P. 
Published: April 2024

The issues of recurrencies in chronic rhinosinusitis with nasal polyps (CRSwNP) still remain unresolved. Therefore, detection patients with uncontrolled clinical course of CRSwNP is required.The aim of the present study was to assess cytokine profile in nasal polyps as well as clinical characteristics of patients with CRSwNP at varying levels of therapeutic control.The study included 99 patients with chronic rhinosinusitis. The contents of interferon IFNγ, interleukin IL- 1β, IL-4, IL-5, IL-13, tumor necrosis factor TNFα, transforming growth factors TGF-β1, TGF-β2, TGF-β3 were measured in polyp tissue samples by means of multiplex analysis. The patients were treated according to a stepwise СRSwNP therapeutic algorithm [9]. Following observation for 5 years, all patients were divided into groups, as based on medical control degree. Group 1 included patients with mild CRSwNP, who mainly received stage I and II treatment for the entire observation period. Group 2 was presented by moderate- severity CRSwNP, with stage II or III therapy according to the referred algorithm. Group 3 included the patients with severe CRSwNP who received one or more stage IV courses. The patients underwent repeated SNOT-22 questionnaire, endoscopic examination, clinical assessment. In case of bronchial asthma (BA), ACQ-7 was repeated. Initial cytokine profile of nasal polyps was analyzed by the mentioned clinical groups.Results:After 5 years of observations in group 1 (mild CRSwNP), we found a minimal decrease in quality of life (SNOT-22), severity of nasal congestion, or smell impairment. Bronchial asthma duration in these patients was significantly lower compared to group 3, the patients had better asthma control level. Cytokine profile of nasal polyps was characterized by the highest IL-4 concentration, average values IL-1β, TNFα, IFNγ and minimal TGF-β1 values.In group 2 (moderate CRSwNP), we noted more pronouced impairment of smell, nasal congestion and quality of life. Bronchial asthma was less controlled than in group 1. The maximal concentrations of IFNγ, IL-1β, TNFα, IL-5, TGF-β1, TGF-β2 were registered.In group 3 with poor CRSwNP control, the highest SNOT-22 scores, severity of difficulty in nasal breathing, impaired sense of smell were revealed. Duration of bronchial asthma was longer, with lowest levels of medical control. In nasal polyps, minimal levels of IFNγ, IL-1β, TNFα, IL-4, IL-5, TGF-β2, TGF-β3 were noted.Treatment of patients depending on the clinical phenotypes of CRSwNP in the presence/absence of allergic rhinitis or bronchial asthma may improve control and reduce incidence of relapses in CRSwNP.
Differing treatment pathways for the management of hypertension: long-term clinical projections in Russia
Authors: Rodionov A. V. , Granados D. , Kontsevaya A. V. 
Published: April 2024

Aim. Management of hypertension, a major cause of mortality worldwide, is difficult, with adherence a common problem. The present study aimed to estimate the long-term clinical outcomes associated with different treatment pathways in people with hypertension in Russia.Material and methods. Outcomes were projected over 10 years using a microsimulation model. Four treatment pathways (current treatment practices (CTP), single drug with dosage titration then sequential addition of other agents [start low and go slow, SLGS], free choice combination with multiple pills (FCC) and combination therapy in a single pill (SPC)) were evaluated based on the Global Burden of Disease 2017 dataset. Clinical outcomes were simulated for 1,000,000 individuals for each pathway.Results. Long-term projections associated SPC therapy with reductions in mortality (4.9%), disability-adjusted life years (DALYs, 5.2%), and incidence of complications (including chronic kidney disease, stroke and ischemic heart disease, 9.2%) versus CTP, with greater reductions in all outcomes versus SLGS and FCC. SPC was projected to save 1,193 DALYs compared with CTP over 10 years. Adherence was identified as a key driver in the analysis.Conclusion. Based on 10-year projections, combination therapies (including SPC and FCC) appear likely to reduce the burden of hypertension compared with conventional treatment options in Russia.
Assessment of inflammatory biomarkers and risk factors for cardiovascular diseases in overweight and obesity
Authors: Murkamilov I. T. , Aitbaev K. A. , Fomin V. V. , Murkamilova Zh. A. , Yusupova Z. F. , Yusupova T. F. , Yusupov F. A. 
Published: April 2024

Aim. To study biomarkers of inflammation in overweight and obese individuals.Material and methods. A total of 180 people with overweight or obesity were included. Anthropometric and biochemical parameters were determined in all patients. The concentrations of C-reactive protein (CRP), fibrinogen, interleukin (IL)-6, IL-10, and tumor necrosis factor alpha (TNF-α) were studied.Results. The following significant correlations have been established: IL-6 — with the levels of central aortic pressure, systolic and diastolic blood pressure (BP), heart rate (HR), levels of glucose, uric acid, low-density lipoprotein cholesterol (LDL-C); TNF-α — with concentrations of uric acid, triglycerides, cystatin C, creatinine and glomerular filtration rate; CRP — with body mass index, diastolic BP, heart rate, levels of uric acid, LDL-C, cystatin C. A significant correlation of IL-6, IL-10 and TNF-α with the proteinuria level was established.Conclusion. In individuals with overweight or obesity, a direct correlation was found between serum concentrations of IL-6 and levels of BP, heart rate, lipids, carbohydrates, uric acid and proteinuria. In overweight or obesity, the serum TNF-α level has a direct correlation with hyperuricemia, hyperfibrinogenemia, hypertriglyceridemia, proteinuria and reduced renal filtration function, and the level of CRP is associated with an increase in diastolic BP, heart rate, uric acid, fibrinogen, LDL-C and cystatin C.
Vital exhaustion as a marker of chronic social stress and smoking among people aged 25-44 years
Authors: Gafarov V. V. , Gromova E. A. , Gagulin I. V. , Panov D. O. , Gafarova A. V. 
Published: April 2024

Aim. To analyze the associations of exhaustion, as a marker of chronic social stress, with smoking in a random representative sample of people aged 25-44 years in Novosibirsk.Material and methods. In Research Institute of Internal and Preventive Medicine — branch of the Institute of Cytology and Genetics, in 2013-2016, a study of a random representative sample of people aged 25-44 years in one of the Novosibirsk districts was conducted (registration № FWNR-2024-0002). A total of 975 individuals were examined, of which 427 men and 548 women. The response rate was >70%. Assessment of exhaustion level and attitude towards smoking was carried out according to standard methods of the World Health Organization's MONICA-psychosocial (MOPSY) program protocol.Results. Among people aged 25-44 years, 38,3% of men and 56,1% of women had exhaustion (χ2=40,744; df=2, p<0,001). Among people of both sexes aged 25-44 years, 58,9% were smokers, of which 27,1% stopped smoking, while 31,8% continued to smoke. Among men, 72,7% smoked, 29% stopped smoking and 43,7% continued smoking. Among women, 48,4% smoked, 25,6% stopped smoking, and 22,8% continued smoking (χ2=72,374; df=5, p<0,001). Among people of both sexes aged 25-44 years with a high exhaustion, 10,5% tried to change their smoking status, but unsuccessfully (χ2=20,708; df=10, p<0,05), and among women — 7,2% (χ2=27,117; df=10, p<0,05). Among those who tried unsuccessfully to change their smoking status (10,1%), "some events annoyed more now than before" (χ2=20,053; df=10, p<0,05). Women who smoke (33%), as well as women who smoke but quit for a while (21,2%) "wanted to die at times" (χ2=20,040; df=10, p<0,05). Among those who smoke, but quit for some time, both among people of both sexes 25-44 years old (14,7%) (χ2=22,783; df=10, p<0,05) and among men (16,1%) (χ2=19,593; df=10, p<0,05) and women (14%) (χ2=20,734; df=10, p<0,05) individually, more often "there was a feeling that recently life requires more strength than is left." Men who tried unsuccessfully to change their smoking status were (13,8%) more often "woke up feeling exhausted and tired" (χ2=19,713; df=10, p<0,05).Conclusion. We found that people with a high exhaustion have greater dependence on smoking.