bluuebunny/crossref_metadata_2025_split huggingface dataset:
Field survey data for conservation: Evaluating suitable habitat of Chinese pangolin at the county‐level in eastern China (2000–2040)
Authors: Liu Wei , Nie Xiaoxiao , Chen Fengjiao , Guo Ning , Zhang Yong , Xiao Shuping , Huang Yanbin , Xie Yanping 
Published: June 2024

AbstractThe scarcity of up‐to‐date data on the distribution and dynamics of the Chinese pangolin (Manis pentadactyla) presented a significant challenge in developing effective conservation strategies and implementing protective measures within China. Currently, most of China's national‐level nature reserves and administrative departments operate at the county level, thereby limiting the applicability of larger‐scale analyses and studies for these administrative entities. This study employed 11 widely used modeling techniques created within the Biomod2 framework to predict suitable habitats for the pangolin at the county scale, while examining the correlation between environmental variables and pangolin distribution. The results revealed that highly suitable habitats in Mingxi County of China encompassed only 49 km2. Within the county‐managed nature reserve, the proportion of highly suitable habitats reached as high as 52%. However, nearly half of these areas, both moderately and highly suitable habitats, remained inadequately addressed and conserved. We found nine administrative villages that necessitated prioritized conservation efforts. The study anticipated an overall expansion in suitable habitats over the ensuing two decades, with significant growth projected in the eastern regions of Xiayang and Hufang Town. This research offered a clear and applicable research paradigm for the specific administrative level at which China operates, particularly pertinent to county‐level jurisdictions with established nature reserves.
The role of bromeliad structural complexity on the presence, spatial distribution and predator avoidance in Tityus neglectus (Scorpiones: Buthidae)
Authors: de Oliveira Souza Maria Carolina , Foerster Stênio Ítalo Araújo , Salomão Renato Portela , Souza‐Alves João Pedro , de Moura Geraldo Jorge Barbosa , Lira André Felipe de Araujo , Ferreira Rodrigo Barbosa 
Published: June 2024

AbstractThe spatial arrangement of organisms is significantly influenced by the structure of vegetation. Bromeliads, characterized by a remarkable architectural design featuring rosette‐like leaf arrangements for rainwater storage, act as habitats for various organisms. These organisms use bromeliads for shelter, foraging, reproduction and the supply of nutrients and moisture. This study investigated how specific aspects of bromeliad structure, such as the number, width and length of leaves, impact the behaviour and distribution patterns of the bromelicolous scorpion Tityus neglectus. In the examination of 110 sampled bromeliads, 33 scorpions were recorded, resulting in an occupancy rate of 30%. The likelihood of scorpion occurrence was associated with the plant's structure. The length and coefficient of variation in the width of leaves appeared as the main predictors, positively influencing scorpion presence while the number of leaves exhibited a negative relation with scorpion occurrence. The distribution of scorpions was uniform across the spatial design of bromeliads. Furthermore, T. neglectus demonstrated the ability to utilize water accumulated in the bromeliad to evade potential predators, submerging itself for, on mean, almost 8 min. We concluded that bromeliad structure is essential in shaping the distribution patterns and anti‐predatory behaviour of T. neglectus.
Colchicine in acute heart failure: Rationale and design of a randomized double‐blind placebo‐controlled trial (COLICA)
Authors: Pascual‐Figal Domingo , Núñez Villota Julio , Pérez‐Martínez Maria Teresa , González‐Juanatey José Ramón , Taibo‐Urquía Mikel , Llàcer Iborra Pau , González‐Martín Javier , Villar Sandra , Soler Meritxel , Mirabet Sonia , Aimo Alberto , Riquelme‐Pérez Alejandro , Anguita Sánchez Manuel , Martínez‐Sellés Manuel , Sánchez Pedro L. , Ibáñez Borja , Bayés‐Genís Antoni ,   on behalf of the COLICA Investigators (see Appendix)
Published: June 2024

AbstractAimsHeart failure (HF) elicits a pro‐inflammatory state, which is associated with impaired clinical outcomes, but no anti‐inflammatory therapies have demonstrated a clinical benefit yet. Inflammatory pathways related with the interleukin‐1 axis are overactivated during episodes of acute HF. Colchicine, an anti‐inflammatory drug with proven benefits in acute pericarditis and ischaemic heart disease, may target this inflammatory response. This study aims to assess the efficacy of colchicine in acute HF patients.MethodsCOLICA is a multicentre, randomized, double‐blind, placebo‐controlled trial enrolling 278 patients across 12 sites. Patients presenting with acute HF, clinical evidence of congestion requiring ≥40 mg of intravenous furosemide and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) >900 pg/ml, are eligible for participation. Patients are enrolled irrespective of left ventricular ejection fraction, HF type (new‐onset or not) and setting (hospital or outpatient clinic). Patients are randomized 1:1 within the first 24 h of presentation to either placebo or colchicine, with an initial loading dose of 2 mg followed by 0.5 mg every 12 h for 8 weeks (reduced dose if <70 kg, >75 years old, or glomerular filtration rate <50 ml/min/1.73 m2). The primary efficacy endpoint is the time‐averaged proportional change in NT‐proBNP concentrations from baseline to week 8. Key secondary and exploratory outcomes include symptoms, diuretic use, worsening HF episodes, related biomarkers of cardiac stress and inflammation, total and cardiovascular readmissions, mortality and safety events.ConclusionCOLICA will be the first randomized trial testing the efficacy and safety of colchicine for acute HF.
Novel 3D textile structures and geometries for electrofluidics
Authors: Abeywardena Sujani B. Y. , Yue Zhilian , Wallace Gordon G. , Innis Peter C. 
Published: June 2024

AbstractThe integration of microfluidics with electric field control, commonly referred to as electrofluidics, has led to new opportunities for biomedical analysis. The requirement for closed microcapillary channels in microfluidics, typically formed via complex microlithographic fabrication approaches, limits the direct accessibility to the separation processes during conventional electrofluidic devices. Textile structures provide an alternative and low‐cost approach to overcome these limitations via providing open and surface‐accessible capillary channels. Herein, we investigate the potential of different 3D textile structures for electrofluidics. In this study, 12 polyester yarns were braided around nylon monofilament cores of different diameters to produce functional 3D core–shell textile structures. Capillary electrophoresis performances of these 3D core–shell textile structures both before and after removing the nylon core were evaluated in terms of mobility and bandwidth of a fluorescence marker compound. It was shown that the fibre arrangement and density govern the inherent capillary formation within these textile structures which also impacts upon the solute analyte mobility and separation bandwidth during electrophoretic studies. Core–shell textile structures with a 0.47 mm nylon core exhibited the highest fluorescein mobility and presented a narrower separation bandwidth. This optimal textile structure was readily converted to different geometries via a simple heat‐setting of the central nylon core. This approach can be used to fabricate an array of miniaturized devices that possess many of the basic functionalities required in electrofluidics while maintaining open surface access that is otherwise impractical in classical approaches.
Numerical simulation of CO2 enhanced condensate gas recovery: A case study in pen 5 gas reservoir
Authors: Wu Min , Li Daoqing , Zhang Yi , Zhao Jinglei , Xie Zehao , Qiu Peng , Sayiti Hasiyati , Sun Haoran 
Published: June 2024

AbstractCO2 flooding is an effective technology for suppling condensate gas reservoir pressure and mitigating global warming. In this study, numerical simulation studies have been conducted to enhance gas recovery in Pen5 condensate gas reservoir using CO2 flooding. Pen5 reservoir has lasted 20 years of primary depletion, which affected by water invasion and retrograde condensation. In numerical simulation study, the GEM module is applied to implement history‐matching of production data, and good agreement has been achieved. Based on comprehensive geological understanding, production dynamics, and numerical simulation techniques, areas with minimal impact from water invasion and retrograde condensation contamination have been delineated. The comparison between continued depletion and the implementation of CO2 injection as a replacement technology in favorable areas has demonstrated the feasibility of CO2 flooding development in these regions. The analysis of the advantages and disadvantages of using miscible flooding and immiscible flooding was conducted, and the optimal development well pattern was evaluated. In the end, the plan of CO2 flooding of Pen5 reservoir has been designed and the gas production rate in the next 10 years has been predicted. The research findings of this study have reference significance for the practical application of CO2 flooding in developing condensate gas reservoirs.
Dairy intake screener as web‐based application is reliable and valid
Authors: Piderit Monique C. , White Zelda , Becker Piet J. , Wenhold Friedeburg A. M. 
Published: June 2024

AbstractThe “Dairy Diary” is a user‐friendly web‐based dairy intake screener. The reliability and validity are unknown. We aimed to evaluate the screener in terms of test–retest reliability and comparative validity. In a diagnostic accuracy study, a purposefully recruited sample of 79 (age: 21.6 ± 3.8 years) undergraduate dietetics/nutrition students from three South African universities completed 3 non‐consecutive days of weighed food records (reference standard) within a seven‐day period (comparative validity), followed by two administrations, 2 weeks apart, of the screener (index test) (reliability). For the four dairy product serving scores (PSSs) and the summative dairy serving scores (DSSs) of the screener and the food records, t‐tests, correlations, Bland–Altman, Kappa, McNemar's, and diagnostic accuracy were determined. For reliability, mean PSSs and DSSs did not differ significantly (p > .05) between the screener administrations. The mean PSSs were strongly correlated: milk (r = .69; p < .001), maas (fermented milk) (r = .72; p < .001), yoghurt (r = .71; p < .001), cheese (r = .74; p < .001). For DSSs, Kappa was moderate (k = 0.45; p < .001). Non‐agreeing responses suggest symmetry (p = .334). For validity, the PSSs of the screener and food records were moderately correlated [milk (r = .30; p = .0129), yoghurt (r = .38; p < .001), cheese (r = .38; p < .001)], with k = 0.31 (p = .006) for DSS. Bland–Altman analyses showed acceptable agreement for DSSs (bias: −0.49; 95% CI: −0.7 to −0.3). Categorized DSSs had high sensitivity (81.4%) and positive predictive value (93.4%), yet low specificity (55.6%) and negative predictive value (27.8%). The area under the receiver operating characteristic curve (0.7) was acceptable. The “Dairy Diary” is test–retest reliable with moderate comparative validity to screen for dairy intake of nutrition‐literate consumers.
Association between drinking water sources and cognitive functioning in Chinese older adults residing in rural areas
Authors: Du Jing , Yang Ling , Duan Ying , Cui Yan , Qi Qi , Liu Zihao , Liu Huaqing 
Published: June 2024

AbstractObjectivesTo explore the association between drinking water sources and cognitive functioning among older adults residing in rural China.MethodsData were extracted from the 2008–2018 Chinese Longitudinal Healthy Longevity Survey. Drinking water sources were categorized according to whether purification measures were employed. The Chinese version of the Mini‐Mental State Examination was used for cognitive functioning assessment, and the score of <24 was considered as having cognitive dysfunction. Cox regression analyses were conducted to derive hazard ratios (HRs) and 95% confidence intervals (CIs) for the effects of various drinking water sources, changes in such sources, and its interaction with exercise on cognition dysfunction.ResultsWe included 2304 respondents aged 79.67 ± 10.02 years; of them, 1084 (44.49%) were men. Our adjusted model revealed that respondents consistently drinking tap water were 21% less likely to experience cognitive dysfunction compared with those drinking untreated water (HR = 0.79, 95% CI: 0.70–0.90). Respondents transitioning from natural to tap water showed were 33% less likely to experience cognitive dysfunction (HR = 0.67, 95% CI: 0.58–0.78). Moreover, the HR (95% CI) for the interaction between drinking tap water and exercising was 0.86 (0.75–1.00) when compared with that between drinking untreated water and not exercising. All results adjusted for age, occupation, exercise, and body mass index.ConclusionsProlonged tap water consumption and switching from untreated water to tap water were associated with a decreased risk of cognitive dysfunction in older individuals. Additionally, exercising and drinking tap water was synergistically associated with the low incidence of cognitive dysfunction. These findings demonstrate the importance of prioritizing drinking water health in rural areas, indicating that purified tap water can enhance cognitive function among older adults.
Properties of the Ammann–Beenker Tiling and its Square Periodic Approximants
Authors: Jagannathan Anuradha , Duneau Michel 
Published: June 2024

AbstractOur understanding of physical properties of quasicrystals owes a great deal to studies of tight‐binding models constructed on quasiperiodic tilings. Among the large number of possible quasiperiodic structures, two dimensional tilings are of particular importance – in their own right, but also for information regarding properties of three dimensional systems. We provide here a users manual for those wishing to construct and study physical properties of the 8‐fold Ammann–Beenker quasicrystal, a good starting point for investigations of two dimensional quasiperiodic systems. This tiling has a relatively straightforward construction. Thus, geometrical properties such as the type and number of local environments can be readily found by simple analytical computations. Transformations of sites under discrete scale changes – called inflations and deflations – are easier to establish compared to the celebrated Penrose tiling, for example. We have aimed to describe the methodology with a minimum of technicalities but in sufficient detail so as to enable non‐specialists to generate quasiperiodic tilings and periodic approximants, with or without disorder. The discussion of properties includes some relations not previously published, and examples with figures.
Development and validation of a nomogram for predicting placenta accreta spectrum in pregnancies with one previous cesarean delivery
Authors: Wu Qianqian , Xi Fangfang , Luo Peiying , Dong Tian , Jiang Hangjin , Luo Qiong 
Published: June 2024

AbstractObjectiveThis study aimed to develop and validate a prenatal nomogram to predict the risk of placenta accreta spectrum (PAS) in women with one previous cesarean delivery.MethodsThis retrospective study enrolled 5157 pregnant women with one previous cesarean delivery in China from January 2021 to January 2023. The nomogram was developed from a training cohort of 3612 pregnant women and tested on a validation cohort of 1545 pregnant women. Multivariate regression analysis was performed using the minimum value of the Akaike information criterion to select prognostic factors that can be included in the nomogram. We evaluated the nomogram by the area under the receiver operating characteristic (ROC) curve, calibration curves, and the decision curve analysis (DCA).ResultsPAS occurred in 199 (5.51%) and 80 (5.18%) patients in the training and validation cohorts, respectively. Backward stepwise algorithms in the multivariable logistic regression model determined abortion, hypertensive disorders complicating pregnancy, fetal position, and placenta previa as relevant PAS predictors. The area under the ROC curve for the nomogram was 0.770 (95% confidence interval [CI] 0.733–0.807) and 0.791 (95% CI 0.730–0.853) for the training and validation cohorts, respectively. The calibration curves indicated that the nomogram's prediction probability was consistent with the actual probability. The DCA curve revealed that the nomogram has potential clinical benefit.ConclusionA prenatal nomogram was developed for PAS in our study, which helped obstetricians determine potential patients with PAS and make sufficient preoperative preparation to reduce maternal and neonatal complications.
Boosting flexible electronics with integration of two‐dimensional materials
Authors: Hou Chongyang , Zhang Shuye , Liu Rui , Gemming Thomas , Bachmatiuk Alicja , Zhao Hongbin , Jia Hao , Huang Shirong , Zhou Weijia , Xu Jian‐Bin , Pang Jinbo , Rümmeli Mark H. , Bi Jinshun , Liu Hong , Cuniberti Gianaurelio 
Published: June 2024

AbstractFlexible electronics has emerged as a continuously growing field of study. Two‐dimensional (2D) materials often act as conductors and electrodes in electronic devices, holding significant promise in the design of high‐performance, flexible electronics. Numerous studies have focused on harnessing the potential of these materials for the development of such devices. However, to date, the incorporation of 2D materials in flexible electronics has rarely been summarized or reviewed. Consequently, there is an urgent need to develop comprehensive reviews for rapid updates on this evolving landscape. This review covers progress in complex material architectures based on 2D materials, including interfaces, heterostructures, and 2D/polymer composites. Additionally, it explores flexible and wearable energy storage and conversion, display and touch technologies, and biomedical applications, together with integrated design solutions. Although the pursuit of high‐performance and high‐sensitivity instruments remains a primary objective, the integrated design of flexible electronics with 2D materials also warrants consideration. By combining multiple functionalities into a singular device, augmented by machine learning and algorithms, we can potentially surpass the performance of existing wearable technologies. Finally, we briefly discuss the future trajectory of this burgeoning field. This review discusses the recent advancements in flexible sensors made from 2D materials and their applications in integrated architecture and device design.
Unusual bendable soft molecule‐based ferroelectric crystals enabling the flexible photo‐pyroelectric detection
Authors: Tang Liwei , Zhu Xinxu , Ma Yu , Xu Haojie , Han Shiguo , Liu Yi , Chen Yaoyao , Wang Daohua , Luo Junhua , Sun Zhihua 
Published: June 2024

AbstractSoft molecule‐based ferroelectrics with unique structural flexibility hold a promise for versatile applications of non‐volatile memory, imaging and photovoltaic devices. Except for few polymers (e.g., polyvinylidene fluoride, PVDF), it is challenging to exploit soft ferroelectric crystals toward free‐standing flexible photoactive devices. We here report a multiaxial soft molecule‐based ferroelectric, (n‐PA)2PbCl4 (1, where n‐PA+ is n‐pentylammonium), of which spontaneous polarization can be reversibly switched in both crystal and powder forms. Strikingly, single crystals of 1 have unusual structural flexibility and bendability, achieving the self‐standing bending with a bending radius of ~0.22 mm. Besides, the pyroelectric activities are also preserved for these single crystals after several bending cycles. Further, the bendable crystal‐based photodetector of 1 allows broadband photoactivities via the photo‐pyroelectric effect, covering a wide range from 405 to 940 nm spectral region, breaking through the limit of optical absorption bandgap. As the first study of bendable free‐standing photo‐pyroelectric detectors in ferroelectric crystals, our work sheds light on the assembly of flexible smart photoelectric devices.image
Effects of adult children's marriage on household stock market participation: An event‐study difference‐in‐differences approach using Chinese micro data
Authors: Sun Haopeng 
Published: June 2024

AbstractThis paper examines households' stock market participation responses to a critical life‐cycle event, adult children's marriage. An event‐study difference‐in‐differences approach is employed to facilitate identification, which compares changes in the stock market participation behaviors of households that experience children's marriage with households that experience it later as well as households that never experience it. Exploiting household‐wide variations in exposure to children's marriage using the China Family Panel Studies data over the 2010–2020 period, this paper finds that 2 years after children's marriage, households significantly enhance their likelihood of participating in the stock market. Households' willingness to participate increases by 1.1 to 1.6 percentage points depending on specifications. This paper's finding supports time‐varying risk aversion at the household level. Mechanism analysis indicates that children's marriage raises household risk preferences because it mitigates parental old‐age support concerns and alleviates households' consumption commitment to housing and children.
A 90‐day preclinical toxicological evaluation in rats of a highly purified and concentrated mulberry leaf extract
Authors: Murbach Timothy S. , Glávits Róbert , Endres John R. , Hirka Gábor , Pasics Szakonyiné Ilona 
Published: June 2024

AbstractMulberry (genus Morus) leaves have long been used as a human food, especially in Asia, and animal feed. More recently, mulberry leaf extracts have been introduced as a convenient way to consume mulberry for non‐nutritional functional effects. Reducose® 5% is an Morus alba leaf extract that has been highly purified and standardized to a content of 5 ± 0.5% 1‐deoxynojirimycin, a naturally present polyhydroxylated piperidine alkaloid analog of D‐glucose. This extract has previously been evaluated in acute and subacute (28‐day) oral toxicity studies in which no adverse effects of the test item were observed in mice or rats, respectively. Due to continued and growing interest in the extract in multinational markets, we have now further investigated potential toxic effects in subchronic (90‐day) oral toxicity study in male and female Han:WIST rats. The test item was administered at doses of 850, 1700, and 2550 mg/kg bw/day, and did not cause adverse effects in clinical signs, body weight development, clinical pathology, gross pathology, or histopathology in comparison to the vehicle‐control group. The no‐observed‐adverse‐effect‐level was determined to be 2550 mg/kg bw/day. These results add to the existing body of both preclinical and clinical work relevant to the safety of the extract and of interest to regulators in various global markets.