bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of salt content on Douchi metabolites: biogenic amines, non‐volatile compounds and volatile compounds
Authors: Li Aijun , Liu Yuchen , Yang Gang , Du Muying , Song Jun , Kan Jianquan 
Published: May 2024

AbstractBACKGROUNDThe excessive salt intake associated with Douchi has become a topic of controversy. Addressing this concern and enhancing its market competitiveness necessitates the application of salt reduction fermentation in Douchi. Therefore, to promote the application of salt reduction fermentation in Douchi, a comprehensive study was undertaken aiming to investigate the differences in biogenic amines, volatile compounds and non‐volatile compounds in Douchi with varying salt content.RESULTSThe findings unequivocally demonstrate that salt hampers the formation of metabolites in Douchi. As the salt content increased, there was a significant decrease (P < 0.05) in the levels of total acid, amino‐type nitrogen and free amino acids in Douchi. Notably, when the salt content exceeded 80 g kg−1, there was a substantial reduction (P < 0.05) in putrescine, lactic acid and malic acid levels. Similarly, when the salt content surpassed 40 g kg−1, β‐phenethylamine and oxalic acid levels exhibited a significant decline (P < 0.05). Furthermore, the results of E‐nose and principal component analysis based on headspace solid phase microextraction gas chromatography–mass spectrometry revealed notable discrepancies in the volatile compound content between Douchi samples with relatively low salt content (40 and 80 g kg−1) and those with relatively high salt content (120, 160 and 200 g kg−1) (P < 0.05). By employing partial least squares discriminant analysis, eight distinct volatile compounds, including o‐xylene, benzaldehyde and 1‐octen‐one, were identified. These compounds exhibited higher concentrations in Douchi samples with relatively low salt content (40 and 80 g kg−1). The sensory results showed that Douchi samples with lower salt content exhibited higher scores in the soy sauce‐like and Douchi aroma attributes.CONCLUSIONIn conclusion, this study significantly enhances our understanding of the impact of salt on metabolites in Douchi and provides invaluable insights for the development of salt reduction fermentation in this context. © 2024 Society of Chemical Industry.
The study on the splicing seam of mini‐light‐emitting‐diode display screen
Authors: Yang Zezhou , Jin Liangliang , Zhao Le , Zhang Shubai , Sun Wenjia , Li Jiaxin , Li Yueqiao , Guan Jun , Chen Xiangyi , Shi Lingyun 
Published: May 2024

AbstractWhen viewing the mini‐LED display screen from a large angle, the seam appearing at the edge of the module can disrupt the uniformity of the entire screen's bright state. This paper studies the formation mechanism of bright and dark seam and color seam from the perspectives of spatial frequency and packaging structure, derives the formula for spatial frequency, analyzes the optical path at the splicing position, and designs a reasonable packaging film structure to solve the color seam.
Adaptive display white point under various ambient conditions
Authors: Guo Jiamin , Wei Minchen , Xie Fei , Jiao Zhiwei 
Published: May 2024

AbstractDisplay technologies have been developed to adjust the display brightness and color under different viewing conditions, providing better viewing experiences to users. Solutions have been proposed to adjust the display white point according to the ambient light condition, which roots into the underlying chromatic adaptation mechanism in the human visual system. This study was carefully designed to reveal the necessity to consider the ambient light level and display luminance together, which affects the viewing mode, when adjusting the adaptive display white point. The results clearly suggested that when the display luminance was greater than the ambient light diffuse white luminance, the display was viewed in the self‐luminous mode and the display white point was not significantly affected by the ambient light chromaticities. In contrast, when the display luminance was lower than the ambient light diffuse white luminance, the display was viewed in the surface mode and the ambient light chromaticities had a significant effect on the display white point, especially when the surround ratio was high.
Efficacy of different indocyanine green doses in fluorescent laparoscopic cholecystectomy: A prospective, randomized, double‐blind trial
Authors: Wang Siyu , Yuan Wenkang , Yu Anhai , Gu Wang , Wang Tianqi , Zhang Chong , Zhang Chao 
Published: May 2024

AbstractBackground and ObjectivesIntraoperative bile duct injury is a significant complication in laparoscopic cholecystectomy (LC). Near‐infrared fluorescence cholangiography (NIFC) can reduce this complication. Therefore, determining the optimal indocyanine green (ICG) dosage for effective NIFC is crucial. This study aimed to determine the optimal ICG dosage for NIFC.MethodsThis was a prospective, randomized, double‐blind clinical trial at a single tertiary referral center, including 195 patients randomly assigned to three groups: lower dose (0.01 mg/BMI) ICG (n = 63), medium dose (0.02 mg/BMI) ICG (n = 68), and higher dose (0.04 mg/BMI) ICG (n = 64). Surgeon satisfaction and detection rates for seven biliary structures were compared among the three dose groups.ResultsDemographic parameters did not significantly differ among the groups. The medium dose (72.1%) and higher dose ICG groups (70.3%) exhibited superior visualization of the common hepatic duct compared to the lower dose group (41.3%) (p < 0.001). No differences existed between the medium and higher dose groups. Similar trends were observed for the common bile duct and cystic common bile duct junction.ConclusionsIn patients undergoing fluorescent laparoscopic cholecystectomy, the 0.02 mg/BMI dose of indocyanine green demonstrated better biliary structure detection rates than the 0.01 mg/BMI dose and was non‐inferior to the 0.04 mg/BMI dose.
Robotic‐assisted total knee arthroplasty is associated with the use of thinner polyethylene liners compared to navigation‐guided and manual techniques
Authors: Cheng Ryan , Kim Billy , Taylor Walter L. , Westrich Geoffrey H. , Shen Tony S. 
Published: May 2024

AbstractPurposeThe purpose of this study was to examine the effects of intraoperative technology use on the rate of using polyethylene liners 15 mm or greater during primary total knee arthroplasty (TKA).MethodsThere were 103,295 implants from 16,386 primary unilateral TKAs performed on 14,253 patients at a single institution between 1 January 2018, and 30 June 2022, included in the current study. Robotic assistance and navigation guidance were used in 1274 (8%) and 8345 (51%) procedures, respectively. The remaining 6767 TKAs (41%) were performed manually. Polyethylene liners were manually identified and further subcategorised by implant thickness. Patients who underwent robotic‐assisted TKA were younger (p < 0.001) and more likely to be male (p < 0.001) compared to patients who underwent navigation‐guided or manual TKAs.ResultsAverage polyethylene liner thickness was similar between groups (10.5 ± 1.5 mm for robotic‐assisted TKAs, 10.9 ± 1.8 mm for navigation‐guided TKAs and 10.8 ± 1.8 mm for manual TKAs). The proportions of polyethylene liners 15 mm or greater used were 4.9%, 3.8% and 1.9% for navigation‐guided, manual and robotic‐assisted procedures, respectively (p < 0.001). Multivariate regression analyses demonstrated that navigation‐guided (odds ratio [OR]: 2.6, 95% confidence Interval [CI]: [1.75–4.07], p < 0.001) and manual (OR: 2.0, 95% CI: [1.34–3.20], p = 0.001) procedures were associated with an increased use of polyethylene liners 15 mm or greater.ConclusionRobotic‐assisted TKA was associated with a lower proportion of polyethylene liners 15 mm or greater used compared to navigation‐guided and manual TKA. These findings suggest that robotic assistance can reduce human error via a more precise cutting system, limit over‐resection of the tibia and flexion‐extension gap mismatch and ultimately allow for more appropriately sized implants.Level of EvidenceLevel III, retrospective cohort study.
An Ovine Model Yields Histology and Gene Expression Changes Consistent with Laryngotracheal Stenosis
Authors: Mafla Laura , So Raymond J. , Collins Samuel L. , Chan‐Li Yee , Lina Ioan , Motz Kevin M. , Hillel Alexander T. 
Published: May 2024

ObjectivesAnimal models for laryngotracheal stenosis (LTS) are critical to understand underlying mechanisms and study new therapies. Current animal models for LTS are limited by small airway sizes compared to human. The objective of this study was to develop and validate a novel, large animal ovine model for LTS.MethodsSheep underwent either bleomycin‐coated polypropylene brush injury to the subglottis (n = 6) or airway stent placement (n = 2) via suspension microlaryngoscopy. Laryngotracheal complexes were harvested 4 weeks following injury or stent placement. For the airway injury group, biopsies (n = 3 at each site) were collected of tracheal scar and distal normal regions, and analyzed for fibrotic gene expression. Lamina propria (LP) thickness was compared between injured and normal areas of trachea.ResultsNo mortality occurred in sheep undergoing airway injury or stent placement. There was no migration of tracheal stents. After protocol optimization, LP thickness was significantly increased in injured trachea (Sheep #3: 529.0 vs. 850.8 um; Sheep #4: 933.0 vs. 1693.2 um; Sheep #5: 743.7 vs. 1378.4 um; Sheep #6: 305.7 vs. 2257.6 um). A significant 62‐fold, 20‐fold, 16‐fold, 16‐fold, and 9‐fold change of COL1, COL3, COL5, FN1, and TGFB1 was observed in injured scar specimen relative to unaffected airway, respectively.ConclusionAn ovine LTS model produces histologic and transcriptional changes consistent with fibrosis seen in human LTS. Airway stent placement in this model is safe and feasible. This large airway model is a reliable and reproducible method to assess the efficacy of novel LTS therapies prior to clinical translation.Level of EvidenceN/A Laryngoscope, 134:4239–4245, 2024
Long‐Term Follow‐Up of Post Radiation Complete Sinus Opacification in Sinonasal Cancer Patients
Authors: Levi Lirit , Havazelet Shany , Moskovitz Anner , Soudry Ethan 
Published: May 2024

ObjectiveTreatment of sinonasal malignancies most often requires primary or postoperative radiation treatment. Post radiation sinonasal morbidity has been previously described; however, none addressed post‐radiation sinus obstruction. Our objective was to investigate the long‐term outcomes of post radiation complete isolated sinus opacification (CISO).MethodsA retrospective analysis of sinonasal cancer patients treated with radiation therapy during the years 2002 to 2022. Clinical, imaging and treatment data were collected from patients' medical records. Only patients with at least 12 months of follow‐up and available imaging for review were included.ResultsOut of 109 patients, 37 patients were identified to meet the inclusion criteria. Mean follow‐up was 58 months. 35% of patients were diagnosed with persistent post radiation CISO with a mean onset of 4 months. All these patients remained asymptomatic, and their imaging remained stable during follow‐up with none developing an expanding mucocele. Ethmoid sinus tumor involvement was found to be more prevalent in the CISO group (62% vs. 25%, p‐value = 0.048) as well as chemotherapy/immunotherapy (54% vs. 38%, p‐value = 0.046). Multivariant analysis revealed that ethmoid sinus involvement (OR = 9.516, p‐value = 0.047) and adjuvant therapy, either chemotherapy/immunotherapy (OR = 10.75, p‐value = 0.036) were found to be a predictive factor for complete opacification.ConclusionOur study revealed that a substantial number of post‐radiation patients develop a stable and persistent CISO, often in the frontal and sphenoid sinuses. These patients remained asymptomatic, and none required surgical intervention during nearly 5 years of follow‐up.Level of Evidence4 Laryngoscope, 134:4232–4238, 2024
SiO2 nanoparticle attenuates phytotoxicity of graphene quantum dots in Zea mays (L.) plants
Authors: Yan Ruifeng , Zhang Yanfeng , Tian Hongyan , Hao Yuan , Sun Haifeng 
Published: May 2024

AbstractThe tremendous potential of graphene quantum dots (gqds) in biomedical applications has raised increasing concerns about their risks to ecosystem and human beings. silicon dioxide nanoparticles (sio2 nps) serve as promising nanofertilizers in enhancing plant tolerance against abiotic stresses, but the knowledge of their role in regulating crop responses to gqd stress is far from sufficient in depth and width. The present work offers insight into the effects of sio2 nps on the root uptake and phytotoxicity of gqds in maize (zea mays L.) seedlings. the addition of sio2 nps significantly decreased the accumulation of gqds in the roots and leaves by 33.3% and 58.8%, respectively. physiologically, the presence of sio2 nps led to substantial enhancement in photosynthesis and antioxidant enzyme activities relative to the plants under the gqds stress. responsive differentially expressed genes were mainly associated with crucial pathways regarding photosynthesis, the mapk signaling pathway in the maize plants, and glutathione metabolism. sio2 nps alleviated the gqds‐induced oxidative stress and helped to re‐establish redox homeostasis by up‐regulating the expression of genes related to antioxidant enzyme activities. these results showed that the root application of sio2 nps alleviated the gqd‐induced inhibition to the photosynthesis and growth of crop plants, which are of great significance for advancing the sustainable utilization of nanofertilizers in agriculture.
Effect of Dicarboxylic Acid Chain Length on the Tribological Properties of Aqueous Polyether Esters
Authors: Shao Wenqiang , Xu Chao , Wang Xiaobo , Liu Xiaoling , Lou Wenjing 
Published: May 2024

ABSTRACTThis article presents the preparation of environmentally friendly water‐soluble lubricant additives. Adipic acid (AA), sebacic acid (SA) and dodecanedioic acid (DA) were individually subjected to esterification reactions with polyethylene glycol 1500 (PEG1500) to prepare a class of water‐soluble polyether esters (AAPEE1500, SAPEE1500 and DAPEE1500) (referred to as XAPEE1500s) that exhibit excellent water solubility and do not contain environmentally harmful elements. First, the molecular structure characterisation and functional group analysis of these additives will be conducted using an infrared spectrometer and a nuclear magnetic resonance spectrometer. Subsequently, the frictional properties of the additives in the base liquid (deionised water) will be investigated using an SRV‐V tribometer, Falex pin‐on‐disc tribometer and screw torque tester. The surface morphology of wear scars will be characterised and analysed using scanning electron microscopy (SEM) and a non‐contact 3D profilometer. Finally, the lubrication mechanism of the DAPEE1500 additive will be analysed using X‐ray photoelectron spectroscopy (XPS). The results indicate that the optimal lubrication performance is achieved when the added mass fraction of DAPEE1500 is at 3%. Compared with 0.5 wt% DAPEE1500, the average friction coefficient of 3 wt% DAPEE1500 decreased from 0.285 to 0.122, and the wear volume decreased from 25.52 × 10−5 μm3 to 10.96 × 10−5 μm3. The lubrication mechanism of polyether ester is the result of the combined action of its polar ester functional groups and long carboxylic acid chains in the structure. These polar functional groups can form a relatively firm adsorption film on the friction surface, while the long carboxylic acid chains act as a brush‐like isolating layer, thus demonstrating superior anti‐wear and anti‐friction performance.
UPHOLDING THE LEADERSHIP LESSONS OF THE LITTLE ROCK NINE
Authors: McArthur Sarah 
Published: May 2024

AbstractThe author, Leader to Leader’s editor‐in‐chief, reflects on how her father was a member of the 327th Infantry Regiment of the 101st Airborne Division of the United States Army, and as such had an important role in US history. She notes that in 1957, “President Dwight D. Eisenhower issued Executive Order 10730 sending my father’s regiment to Central High School in Little Rock, Arkansas to maintain order as the school was desegregated.” This Executive Order “placed the Arkansas National Guard under federal authority and sent 1,000 US Army troops to Little Rock to enforce the US Supreme Court’s 1954 ruling in Brown v. the Board of Education that US State laws establishing segregation in public schools are unconstitutional, even if the segregated schools are otherwise equal in quality.” She relates that her father “ … remembers feeling the volatility of the situation that did not ignite, he believes, because of the discipline and presence of the 101st.” These thoughts resonated with her as she later interviewed the retired Army General Dennis J. Reimer, who in the 1990s was Chief of Staff of the United States Army, for her forthcoming documentary about our journal’s founder, Frances Hesselbein.
Transcription factor EHF drives cholangiocarcinoma development through transcriptional activation of glioma‐associated oncogene homolog 1 and chemokine CCL2
Authors: Luo Yiming , Li Zhi , Zhu He , Lu Junli , Lei Zhen , Su Chen , Liu Furong , Zhang Hongwei , Huang Qibo , Han Shenqi , Rao Dean , Wang Tiantian , Chen Xiaoping , Cao Hong , Zhang Zhiwei , Huang Wenjie , Liang Huifang 
Published: May 2024

AbstractCholangiocarcinoma (CCA) is characterized by rapid onset and high chance of metastasis. Therefore, identification of novel therapeutic targets is imperative. E26 transformation‐specific homologous factor (EHF), a member of the E26 transformation‐specific transcription factor family, plays a pivotal role in epithelial cell differentiation and cancer progression. However, its precise role in CCA remains unclear. In this study, through in vitro and in vivo experiments, we demonstrated that EHF plays a profound role in promoting CCA by transcriptional activation of glioma‐associated oncogene homolog 1 (GLI1). Moreover, EHF significantly recruited and activated tumor‐associated macrophages (TAMs) through the C‐C motif chemokine 2/C‐C chemokine receptor type 2 (CCL2/CCR2) axis, thereby remodeling the tumor microenvironment. In human CCA tissues, EHF expression was positively correlated with GLI1 and CCL2 expression, and patients with co‐expression of EHF/GLI1 or EHF/CCL2 had the most adverse prognosis. Furthermore, the combination of the GLI1 inhibitor, GANT58, and CCR2 inhibitor, INCB3344, substantially reduced the occurrence of EHF‐mediated CCA. In summary, our findings suggest that EHF is a potential prognostic biomarker for patients with CCA, while also advocating the therapeutic approach of combined targeting of GLI1 and CCL2/CCR2‐TAMs to inhibit EHF‐driven CCA development.
Examining the impact of board gender diversity and regional differentiation in the ESG‐corporate performance nexus: Evidence from financial service industry
Authors: Tran Thu Huong , Lu Wen‐Min , Ting Irene Wei Kiong , Huang Hsueh‐Li ( Shirley) , Fauzi Muhammad Ashraf 
Published: May 2024

AbstractThis study explores the impact of environmental, social, and governance (ESG) factors on corporations by investigating how board gender diversity moderates the relationship between ESG practices and corporate performance across different regions. Using traditional data envelopment analysis (DEA) and chance‐constrained DEA models, the study analyzes 225 financial service firms over an 11‐year period (2011–2021). Results indicate that high (low) board gender diversity levels significantly influence the connection between the environmental (social) aspects of ESG practices and corporate performance. Thus, the roles of stakeholder engagement and regional distinctions are highlighted in achieving sustainable development goals.
Privacy‐preserving data aggregation achieving completeness of data queries in smart grid
Authors: Li Xinyang , Zhao Meng , Ding Yong , Yang Changsong , Wang Huiyong , Liang Hai , Wang Yujue 
Published: May 2024

AbstractIn smart grid systems, the control center formulates strategies and provides services by analyzing electricity consumption data. However, ensuring the privacy and security of user data is a critical concern. While traditional data aggregation schemes can provide a certain level of privacy protection for users, they also impose limitations on the control center's access to fine‐grained data. To address these challenges, we propose a privacy‐preserving data aggregation scheme supporting data query (PAQ). We designed a multi‐level data aggregation mechanism based on Paillier semi‐homomorphic encryption to achieve efficient aggregation of user data in the control center. Additionally, a data query mechanism based on electricity consumption intervals is introduced, allowing the control center to query aggregated ciphertexts for different user categories from outsourced data on the cloud server. Security analysis demonstrates that PAQ design effectively solves security issues in data aggregation and query processes. Performance analysis indicates that the proposed scheme outperforms existing solutions in terms of efficiency.
Performance of security options for message protocols: A comparative analysis
Authors: dos Reis Bezerra Wesley , Koch Fernando , Becker Westphall Carlos 
Published: May 2024

AbstractWe explore the challenges around security configuration and performance while utilizing publish–subscribe protocols in the Internet of Things, edge computing, and fog computing. Issues in security configuration can lead to disruptions and higher operation costs. These issues can be prevented by selecting the appropriate transmission technology for each configuration, considering the variations in sizing, installation, sensor profile, distribution, security, networking, and locality. We introduce a comparative analysis of different configurations around a smart agriculture use case. For that, we implemented a simulation environment to generate datasets relevant to research and compare the results in terms of performance, resource utilization, security, and resilience—focused on authentication process. This analysis provides a blueprint to decision support for fog computing engineers on the best practices around security configurations.