bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemistry of small ring compounds Part 15: The kinetics of the Cannizzaro reaction of cyclopropanecarbaldehyde
Authors: van der Maeden F. P. B. , Steinberg H. , de Boer Th. J. 
Published: September 2010

AbstractIn aqueous sodium hydroxide, cyclopropanecarbaldehyde 1 disproportionates exclusively into cyclopropylmethanol 2 and cyclopropanecarboxylic acid 3 (Cannizzaro reaction). The reaction is second order in aldehyde and second order in base and shows a small positive salt effect. These results and the absence of deuterium incorporation in the alcohol 2, when the reaction is carried out in D2O, have been rationalized in scheme 1.The enthalpy and entropy of activation are found to be ΔH ≠ = 11.7 ± 0.6 kcal/mole and ΔS ≠ = −17.5 ± 1.0 e.u. (74°). The results of the crossed Cannizzaro reaction between benzaldehyde and cyclopropanecarbaldehyde suggests that cyclopropyl is a better electron‐donating group than phenyl.
Some remarks concerning the interpretation of shifts in carbon(1s) electron binding energies
Authors: Bus J. , de Jong S. 
Published: September 2010

AbstractThe carbon (1s) electron binding energies (Eb) of methyl acetate (CH3:285.6, CO: 289.5 and OCH3: 286.5 eV) correlate well with CNDO/2‐charges (slope 5.6 eV/unit charge), with Pauling charges (slope 5.1) and with Extended Hückel charges (slope 2.4).If the Eb‐values are corrected for molecular potentials (V), again good correlations are found (slope 22.0, 20.9 and 18.6 resp.). Because it did not make much difference which method was used for calculating charges (q), tests have been made to establish whether charge calculations based on electronegativities could be used for a large series of C(1s) binding energies. For adjacent charges of equal signs, a correction was introduced and it was also found that Jolly's (or Johnson's) electronegativity values gave better results than the Pauling values.Resonably good correlations were obtained for the function Eb = α + βq + κV with κ = 0, κ = 1 and κ ≠ 0. Introduction of a γq2 term did not improve the correlation. The best fit was obtained with Eb = 285.3 + 11.75 q + 0.48 V ± 0.8 (st. dev.).
NMR and X‐ray diffraction spectra of two hexachloro addition products of biphenyl (E and A); the molecular structures of E and A; the crystal structure of E
Authors: de Mey Catharina A. , de Kok A. J. , Lugtenburg J. , Romers C. 
Published: September 2010

AbstractCrystals of the title compounds are monoclinic. The lattice constants of the first compound (E) are: a = 16.33, b = 6.48, c = 6.96 Å and β = 91.03° at 20°C. Its space group is P21 and Z = 2. The configuration follows from a three‐dimensional X‐ray analysis and turns out to be 1e,2e,3e,4e,5e,6e‐hexachloro‐1a‐phenylcyclohexane. The conformation is described by means of Newman projections. The sum of C‐Cl vectors is not zero and results in a calculated electric moment of 1.06 D, the experimental value being 1.65 D.The lattice constants of the second compound (A) are: a = 20.0, b = 10.8, c = 15.2 Å and β = 112.4° at 20°C. The space group is P21/c and Z = 8.The interpretation of the NMR spectrum of E agrees quite well with the X‐ray analysis. The configuration of A was established by combined NMR (100 and 220 MHz) and 13CNMR techniques, its molecular structure being 1a,2a,3e,4e,5e,6e‐hexachloro‐1e‐phenylcyclohexane.
Activity coefficients of single ions III: The difference between the standard chemical potentials of single ions in methanol and methanol‐water mixtures and in water at 25°C, and some related quantities
Authors: Bax D. , de Ligny C. L. , Alfenaar M. 
Published: September 2010

AbstractThe method described by De Ligny et al. for the estimation of activity coefficients of single ions, which originated from ideas of Alfenaar and De Ligny, Buckingham, Halliwell and Nyburg and Muirhead‐Gould and Laidler, has been improved further.The modified method was applied successfully to the transfer of ions from water to methanol and methanol‐water mixtures.A similar method was used to estimate the standard partial molar enthalpy of transfer ΔH° of single ions, and from these data values for the standard partial molar entropy of transfer ΔS° were obtained.The differences between the standard real potentials of the chloride ion in methanol and methanol‐water mixtures, and in water have been determined by Case and Parsons. From these data, the corresponding differences for the standard chemical potentials and the surface potential of water, the surface potentials of methanol and methanol‐water mixtures, were determined.
Chemistry of acetylenic ethers 97: Claisen‐rearrangement of 1‐alkynyl allenyl sulfides synthesis of acetylenic thioamides and derivatives of thiophene
Authors: Meijer J. , Brandsma L. 
Published: September 2010

Abstract1‐Alkynyl allenyl sulfides H2C=C=CHSC≡ CR1 (R1 = CH3, C2H5), prepared from alkynethiolates LiSC≡CR1 and propargyl bromide in liquid ammonia, rearrange at room temperature to thioketenes HC≡CCH2C(R1)=C=S. These can be trapped by amines R22NH (R2 = C2H5, C3H7) to give the acetylenic thioamides H≡CCH2CH(R1)C(=S)NR22 in fair to good yields. Potassium tert‐butoxide in liquid ammonia causes cyclization of the thioamides to 2‐dialkylamino‐3,5‐dialkylthiophenes. The same thiophenes are obtained by simply heating the thioamides in hexamethylphosphoric triamide.
Electrocyclic reactions in a cyclohexadiene‐hexatriene system
Authors: Gaasbeek C. J. , Hogeveen H. , Volger H. C. 
Published: September 2010

AbstractIn a consecutive series of stereospecific reactions under alternately thermal and photochemical conditions cis‐1,2,3,4,5,6‐hexamethylcyclohexa‐1,3‐diene I, 3,4,5,6‐tetramethyl‐(Z,Z,E)‐octa‐2,4,6‐triene II, transf‐1,2,3,4,5,6‐hexamethylcyclohexa‐1,3‐diene III and 3,4,5,6‐tetramethyl‐(Z,Z,Z)‐octa‐2,4,6‐triene IV have been synthesized from 1,2,3,4,5‐endo,6‐endo‐hexamethylbicyclo[2.2.0] hex‐2‐ene as the starting material. Thermal ring closure of the triene IV did not give the cis‐diene I, but, among other products, the trans‐diene III. An intermediate product in this reaction is 3,4,5,6‐tetramethyl‐(Z,Z)‐octa‐1,3,5‐triene V, formed via a [1,7a] H shift.The structure of compound IV has been assigned on the basis of chemical and spectroscopic (13C and 220 MHz 1H NMR) data.Cis‐diene I can, at room temperature, be converted direct into trans‐diene III under the influence of hydrochloric acid.
Asymmetric synthesis of optically active 6‐thiaestrogens
Authors: Könst W. M. B. , Speckamp W. N. , Houwen H. O. , Huisman H. O. 
Published: September 2010

Abstract(13S,17S)‐6‐Thiaestrogens have been synthesized by asymmetric conversion of the corresponding 8,14‐seco‐steroid.
Pyrazoles and imidazoles as ligands. Part XI: Mössbauer spectra of tetragonal pyrazole complexes of Fe(II)
Authors: Reedijk J. , Engelfriet D. W. 
Published: September 2010

AbstractCompounds of the type Fe(ligand)4(anion)2, with pyrazole and 5‐methylpyrazole as ligands, and I−, Br−, Cl−, NO−3 and NCS− as anions, have been investigated by Mössbauer spectroscopy at 300 and 90° K.The observed centre shifts of the compounds are in the 1.29‐1.33 mm/s range at room temperature and 1.42‐1.45 mm/s range at liquid nitrogen temperatures, and fall in the lower range of the region found for Fe(II) in the high‐spin state. The observed quadrupole splittings were found to be largely dependent upon the particular combination of ligand and anion, and, for some compounds also upon the temperature.Comparison of the quadrupole splittings with previously obtained ligandfield parameters confirms the 5Eg ground state for the Fe(II) ion, and agrees with a tetragonal symmetry for the species FeL4A2. In addition, small rhombic distortions were found to be present for the compounds with the ligand 5‐methylpyrazole. A 5B2g ground state is proposed for Fe(pyrazole)4(NCS)2.In all compounds the splitting of the octahedral 5T2g state is quite large, placing the 5B2g level about 2‐3 kK above the 5Eg state.The lattice contribution to the quadrupole splitting (0.8‐1.6 mm/s for most compounds) is shown to be much larger than previously assumed for high‐spin Fe(II).
Gas phase reaction of ethene with carbonyl sulfide and carbon disulfide in a silent electrical discharge
Authors: van Drumpt J. D. 
Published: September 2010

AbstractThe gas phase reaction between ethene and COS or CS2 in a silent electrical discharge at atmospheric pressure is described. In both cases S(3P) and S(1D) atoms are formed, which react with ethene to give epithioethane and ethenethiol besides minor amounts of polymer.
Stereoselectivity in the complex formation of penicillamine with nickel(II)
Authors: Ritsma J. H. , Jellinek F. 
Published: September 2010

AbstractStability constants of nickel(II) and zinc complexes of optically active and racemic cysteine and penicillamine (dianion: penam) in aqueous solution have been determined. For the complex Ni(penam)22− a significant stereoselective effect in favour of the racemic mixture (MLL + MDD) was observed, the meso complex MDL having an excess Gibbs energy of 0.5‐0.6 kcal/mole (2.1‐2.5 kJ/mole) relative to the racemic mixture. For Zn(penam)22− a small effect, on the edge of significance, in favour of the meso complex MDL was found; no stereoselectivity was observed for the cysteine complexes.
Activity coefficients of single ions IV.: The difference between the standard chemical potentials of single ions in ethanol and ethanol‐water mixtures and in water at 25°, and some related quantities
Authors: Bax D. , de Ligny C. L. , Remijnse A. G. 
Published: September 2010

AbstractA method for the estimation of standard chemical potential differences (Δμ°) of single ions for the transfer from one solvent to another, derived previously, is applied to the transfer of ions from water to ethanol and ethanol‐water mixtures.A similar method is used to estimate the standard partial molar enthalpy of transfer, ΔH° of single ions, and from these data values for the standard partial entropy of transfer, ΔS° are obtained.The difference between the standard real potentials of the chloride ion in ethanol and in water has been determined by Case and Parsons. From these data, the corresponding value of Δμ° and the surface potential of water, the surface potential of ethanol is determined.
Kinetics and mechanism of urethane formation in DMF: The reaction of 4, 4′‐di‐isocyanatodiphenylmethane with alcohols
Authors: Borkent G. , van Aartsen J. J. 
Published: September 2010

AbstractThe rate constants of reactions between 4, 4′‐di‐isocyanato‐diphenylmethane (MDI) and alcohols in N, N‐dimethylformamide (DMF) have been determined by an UV‐spectroscopic method. On the basis of the kinetics observed and the values of the activation parameters ΔS ≠ and ΔH ≠, a proposal is made for a mechanism with a four‐centre transition state. The rate constants for the reaction of several alcohols with MDI in DMF are correlated with the extended Taft equation:
equation image
(Ecs = corrected steric substituent constant according to Hancock).
The synthesis of 14α, 17α‐alkylidenedioxy‐9α‐and 9β‐estrane derivatives. Stereospecific reduction of Δ9(11)‐steroids
Authors: Kooreman H. J. , van der Sijde D. , Marx A. F. 
Published: September 2010

AbstractCatalytic hydrogenation of the 9(11)‐double bond of 3, 14α, 17α‐trihydroxy‐19‐nor‐1, 3, 5(10), 9(11)‐pregnatetraen‐20‐one (1a) furnished a mixture of the 9α‐ and 9β‐stereoisomers.In the case of the 14α, 17α‐ethylidenedioxy‐derivatives 4a and 4b the 9β‐isomers were obtained almost exclusively.Reduction of 14α, 17α‐ethylidenedioxy‐3‐methoxy‐1, 3, 5(10), 9(11)‐pregnatetraen‐20‐one (4b) with sodium in liquid ammonia gave the steroisomeric 9α‐compounds (5b).The stereochemistry of the compounds was determined by NMR‐spectroscopy.
Formation and PMR spectra of arene dipositive ions
Authors: Brouwer D. M. , van Doorn J. A. 
Published: September 2010

AbstractPerylene, naphthacene, anthracene and some substituted anthracenes are oxidized to the dipositive ions by SbF5 (neat or in SO2CIF). In FSO3H‐SbF5 dication formation takes only place with the easily oxidizable arenes perylene and naphthacene. The dication of anthracene has also been obtained by bromide abstraction from 9, 10‐dibromo‐9, 10‐dihydroanthracene. The PMR spectra of the dications are reported. Like in the dianions, the sum of the charge‐induced shifts varies considerably from one arene to the other.
Activation and transfer of oxygen VII: Synthesis and spontaneous oxidation of some 1, 8‐blocked tetrahydropteridines
Authors: Mager H. I. X. , Berends W. 
Published: September 2010

AbstractSome tetrahydropteridines carrying methyl substituents at the N(1)‐, N(3)‐and N(8)‐positions were synthesized and subjected to autoxidation (V and XIII). A spontaneous oxidative contraction of the pyrimidine ring occurred in aqueous solution (XIII + O2 → XXI). This result was in agreement with a theory which has already been put forward.5‐Acetyl‐tetrahydropteridines were required for synthetic purposes. They could not generally be prepared by reduction of pteridines with zinc/acetic acid/acetic anhydride. A contraction of the pyrazine ring occurred in the attempted reductive acetylation of 1, 3, 6, 7‐tetramethylpteri‐2, 4‐dione (IX). The product was identified as 1, 3, 8‐trimethyl‐2, 6‐dioxopurine (XIV = 8‐methyl‐theophylline). Starting from 1, 3‐dimethylpteri‐2, 4‐dione the same procedure led to a mixture of two dimeric acetyl‐tetrahydropteridine derivatives.
On the mechanism of the amination of 4‐halogeno‐6‐phenylpyrimidines with potassium amide in liquid ammonia
Authors: de Valk J. , van der Plas H. C. 
Published: September 2010

AbstractThe synthesis of the 4‐chloro‐, 4‐iodo‐ and 4‐fluoro derivatives of 6‐phenyl‐[1(3)‐15N]pyrimidine is described. The amination of 4‐chloro‐ and 4‐fluoro–6‐phenyl‐[1(3)‐15N]pyrimidine with potassium amide in liquid ammonia at −75° occurs to a great extent (93% ± 5% and 73% ± 5%, respectively) according to the ANRORC‐mechanism. In the conversion of 4‐iodo‐6‐phenyl‐pyrimidine into the corresponding 4‐amino compound the ANRORC‐mechanism occurs to the extent of about 10% only; evidence has been put forward that in this conversion an EA‐mechanism is mainly operative.
Tetrakis(t‐butyl isocyanide)nickel(II) perchlorate
Authors: Stephany R. W. , Drenth W. 
Published: September 2010

AbstractNi(CN‐t‐C4H9)4(H2O)2(ClO4)2 has been prepared and reversibly converted to Ni(CN‐t‐C4H9)4(ClO4)2. Infrared, electronic, proton magnetic resonance and some X‐ray data are provided.
Studies on vitamin D and related compounds XXII: New reactions and products in vitamin D3 photochemistry
Authors: Bakker S. A. , Lugtenburg J. , Havinga E. 
Published: September 2010

AbstractFrom the mixtures resulting from U.V. irradiation (λ > 250 nm) of solutions of vitamin D3 in ethanol four novel products could be isolated besides suprasterols3 I and II. The NMR and other data suggest that two of the new compounds found are stereoisomeric vinylallene derivatives, whereas the two others may represent cyclobutene derivatives (Fig. 3). The six photoproducts of vitamin D3 correspond to what would be expected from a 1,3,5‐hexatriene occurring in a s‐trans‐Δ3‐cis‐s‐cis conformation.
Aromatic lead(IV) compounds. III: The plumbylation of aromatic ethers in the presence of halogen‐substituted acetic acids: (Preliminary communication)
Authors: de Vos D. , Spierenburg J. , Wolters J. 
Published: September 2010

AbstractThe widened scope of the improved method of plumbylation of aromatic ethers has made novel aryllead(IV) compounds accessible.
Mannich‐type condensation reactions of sulfinic acids with aldehydes and nitrogen bases: Part. VI. The use of ureas, thioureas and thiobenzamide
Authors: Meijer H. , Tel R. M. , Strating J. , Engberts J. B. F. N. 
Published: September 2010

AbstractUrea, thiourea and some N′‐alkyl(di)substituted ureas and thioureas were found to react as the amine component in Mannich‐type condensation reactions with p‐toluene‐ or phenylmethane‐sulfinic acid and aldehydes. Mono‐ or di‐alkylation products are formed in good yields depending on the N′‐ and N′‐substituents in the substrate, while N,N,N′‐trimethylurea or ‐thiourea failed to react. N′‐Hydroxy‐N′‐phenylthiourea is alkylated on the N′‐atom bearing the OH‐substituent as demonstrated by the ESR spectrum of the thioacyl nitroxide derived from the condensation product. Thiobenzamide, in contrast with thioacetamide, also condensed with p‐toluenesulfinic acid and formaldehyde or N′‐butyraldehyde. With benzaldehyde, however, Mannich‐type condensation did not occur and 3,5‐diphenyl‐1,2,4‐thiadiazole was isolated instead.The NMR spectra of several urea and thiourea condensation products provided evidence for hindered internal rotation in the urea and thiourea function and some ΔG≠ values for the exchange process were estimated. Intramolecular shielding effects were observed in the NMR spectrum of 4c and 4f indicating the occurrence of folded conformations.
Isolation of purine oligonucleotides after hydrazinolysis of deoxyribonucleic acid
Authors: Havelaar K. J. , de Waard A. 
Published: September 2010

AbstractA modified version of the classical degradation of deoxyribonucleic acid by hydrazine has been used to obtain undamaged purine‐deoxyribo oligonucleotides. This method exploits hydraziniumchloride as a reagent capable of β‐elimination of the phosphate ester group from C(3) of a deoxyribose originally carrying a pyrimidine. Alkaline hydrolysis completes the required scission of the sugar‐phosphate backbone and removes remnants of the pyrimidine skeleton still attached to some deoxyribose residues. A novel type of reaction of alkaline phosphatase from E. coli was used with advantage to free the purine‐isostychs from substitution products of deoxyribose originally carrying a pyrimidine. The resulting purine‐isostychs have been separated and characterized.
Synthesis of human growth hormone sequences. Solid‐phase synthesis of protected 1‐10 and 6‐10 HGH
Authors: de Leer E. W. B. , Beyerman H. C. 
Published: September 2010

AbstractThe solid‐phase synthesis of the fully protected N‐terminal decapeptide sequence of human growth hormone, Boc‐Phe‐Pro‐Thr(ZTF)‐Ile‐Pro‐Leu‐Ser(Bzl)‐Arg‐(NO2)‐Leu‐Phe‐OMe, and the sequence 6‐10, Boc‐Leu‐Ser(Bzl)‐Arg(NO2)‐Leu‐Phe‐OMe, is described. The synthesis of the decapeptide was carried out twice, once with Boc‐amino acid couplings only, and once with dipeptide couplings of Boc‐Ile‐Pro and Boc‐Phe‐Pro. The products were purified by gel chromatography; the product obtained by the first method then still contained an impurity.
Investigation of 90° and 180° superexchange interactions of Ni2+ in MgO by means of magnetic susceptibility methods
Authors: van Leeuwen G. C. M. , van Driel J. C. 
Published: September 2010

AbstractMagnetic susceptibility measurements in the temperature range of 4‐300°K have been performed on different NixMg1−xO samples with x ranging from 0.0068 to 0.0465. Typical temperature dependent deviations from the single‐ionsusceptibility were observed for all samples. These deviations have been explained by taking into account the effect of both 90° and 180° superexchange interactions. Assuming a random distribution of Ni2+ ions over the Mg2+ sites, the contributions from the various bi‐ and tri‐nuclear clusters to the total susceptibility have been found to check with experiment for J(90°)/k = 2.3 ± 0.2°K and J(180°)/k = 150 ± 10°K.
Synthesis of the pyrroline analogue of nigrifactin: A new oxidation reaction with lead tetra‐acetate
Authors: de Koning H. , Springer‐Fidder A. , Moolenaar M. J. , Huisman H. O. 
Published: September 2010

AbstractThe pyrroline analogue of nigrifactin ‐ 2‐(1,3,5‐heptatrienyl)‐1‐pyrroline (2) ‐ has been synthesized. A key‐step is oxidation of 2‐hydroxymethyl‐1‐tritylpiperidine (6) with lead tetra‐acetate in presence of pyridine, leading to the formation of 2‐diacetoxymethyl‐1‐tritylpyrrolidine (7). The mechanism of this oxidation reaction is discussed.
Synthesis of 2trans‐alkene‐mono‐and ‐poly‐ynoic acids with a triple bond in the 5‐position and their hydrogenation. A new synthesis of arachidonic acid
Authors: Heslinga L. , Pabon H. J. J. , van Dorp D. A. 
Published: September 2010

Abstract27Trans‐alkenoic, 2trans‐alkenemonoynoic and 2trans‐alkenepolyynoic acids with the first triple bond in the 5‐position could be obtained in high yield by coupling 1‐alkyl‐ and 1‐mono‐ or ‐poly‐ynylmagnesium bromides with 4‐bromocrotonic acid in tetrahydrofuran at low temperature.By hydrogenation in the presence of Lindlar's catalyst, cis polyenoic acids with a 2trans double bond have been synthesized. On continued hydrogenation, the 2trans double bond can be removed selectively. This new method has been applied to the synthesis of 2trans,5cis,8cis,11cis,14cis‐eicosapentaenoic acid and its hydrogenation to 5cis,8cis,11cis,14cis‐eicosatetraenoic acid (arachidonic acid).
Ring transformations in reactions of heterocyclic halogeno compounds with nucleophiles (XXVIII) A study of the mechanism of transformation of chloropyrazine into 2‐cyanoimidazole using 14C‐ and 15N‐labelling
Authors: Lont P. J. , van der Plas H. C. 
Published: September 2010

AbstractThe mechanism of the conversion of chloropyrazine into 2‐cyanoimidazole by the action of potassium amide in liquid ammonia has been investigated. Using 2‐chloro[4′ 15N]pyrazine and 2‐chloro[2′ 14C]pyrazine it has been shown that ring contraction occurs by a nucleophilic attack of the amide ion at C(3), followed by fission of the C(3)‐N(4) bond.
ESCA‐Investigations of thallium(I) salts of β‐dicarbonyl compounds
Authors: Kolind‐Andersen H. , Lawesson S.‐O. , Larsson R. 
Published: September 2010

AbstractThe binding energies of the Tl(4f5/2) electrons in various thallium(I) salts of β‐dicarbonyl compounds have been measured. The mean value is considered as the “group shift”. The influence of the substituents on the binding energy of the core electrons in the thallium atom is of second order. No systematic influence on the binding energies of the Tl(4f5/2) electrons is found from the substituents on the heterocyclic six‐membered ring, formed by the ligand and the metal atom.
Nigrifactin analogues: Synthesis of some hetero‐aromatic polyenes via the Horner reaction
Authors: de Koning H. , Mallo G. N. , Springer‐Fidder A. , Subramanian‐Erhart K. E. C. , Huisman H. O. 
Published: September 2010

AbstractSome all‐trans 1,3,5‐heptatrienyl and 6‐ethoxycarbonyl‐1,3,5‐hexatrienyl substituted heterocyclic compounds have been synthesized, employing Horner reactions of heterocyclic aldehydes or heterocyclic methylphosphonates.
Hydride transfer reactions: II. Hydride transfer from alkanes to methyloxocarbonium ion
Authors: Brouwer D. M. , Kiffen A. A. 
Published: September 2010

AbstractThe hydride transfer from some alkanes to acetyl cation (methyloxocarbonium ion, 1), which yields acetaldehyde and alkylcarbonium ions as the primary products, has been investigated in HF solution. In HFBF3 the reaction of isobutane with 1 affords protonated mesityl oxide and protonated ethyl acetate as the first observable products. The former ion arises from acetylation of isobutene and the latter through rapid abstraction of hydride from isobutane by protonated acetaldehyde, followed by acetylation of the ethanol thus formed. Similar results were obtained with isopentane and methylcyclohexane. In 9:1 HFSbF5, reaction of 1 with isobutane gives t‐butyl ion and protonated ethanol. The rates are the same in HFSbF5 and HFBF3 (k ∼ 10−4M−1s−1 at 20°C), which shows that the hydride transfer to oxocarbonium carbon is not assisted by protonation of the incipient aldehyde. Hydride abstraction by 1 from n‐butane is slower than that from isobutane by a factor of at least 103.The present results are compared with those obtained in the reactions of (cyclo)alkanes with acetyl chloride‐aluminium chloride.
The formation of a 1‐methyl‐2‐(4‐pyrimidinyl)hydrazine from a di‐4‐pyrimidinyl carbonate and methylhydrazine
Authors: Dekker W. H. 
Published: September 2010

AbstractThe reaction between methylhydrazine and bis[2‐(dimethylamino)‐5,6‐dimethyl‐4‐pyrimidinyl] carbonate leads to 1‐[2‐(dimethylamino)‐5,6‐dimethyl‐4‐pyrimidinyl]‐2‐methylhydrazine instead of the expected 2‐(dimethylamino)‐5,6‐dimethyl‐4‐pyrimidinyl 2‐methylcarbazate.