bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demodex mite infestation in patients with and without rheumatoid arthritis
Authors: Garbacewicz Aleksandra , Jaworski Janusz , Grytner-Zięcina Barbara 
Published: February 2012

AbstractIn the present study we compared the prevalence of Demodex mites in patients with rheumatoid arthritis and in one control group involving individuals of similar mean age. From each person we epilated 3–4 lashes from each eyelid and examined them under a microscope to find Demodex mites. In total 147 patients were examined. The prevalence of Demodex mites was 33% in rheumatoid arthritis (RA) patients and 31% in the control group. Our results demonstrated that the prevalence of Demodex mites was similar in RA patients as compared to the control group.
Is the community of fish gill parasites structured in a Neotropical floodplain?
Authors: Bellay Sybelle , Takemoto Ricardo , Oliveira Edson 
Published: February 2012

AbstractSixty-one specimens of the piranha Serrasalmus marginatus Valenciennes, 1837 were analyzed, aiming at assessing the community structure of their gill parasites. The samples were collected in lagoons of the Paraná, Ivinheima and Baia Subsystems within the Upper Paraná River Floodplain (Brazil). Host size and sex had little or no influence on the abundance and prevalence of parasites. The organization of the gill parasite infracommunities of S. marginatus was significantly non-random according to null models and ordination analyses. In general, parasite infrapopulations were not affected by interspecific associations or host characteristics (e.g. size, sex), what highlights the importance of local habitat characteristics to community organization of gill parasites of S. marginatus in the Upper Paraná River Floodplain.
Rhabdochona (Rhabdochona) keralaensis sp. nov. (Rhabdochonidae) and some other nematodes in the Indian mottled eel Anguilla bengalensis bengalensis from India
Authors: Moravec František , Sheeba Sarasamma , Kumar Appukuttannair 
Published: February 2012

AbstractA new species of parasitic nematode, Rhabdochona (Rhabdochona) keralaensis sp. nov., is described based on specimens recovered from the intestine of Anguilla bengalensis bengalensis (Gray) collected from the freshwater bodies of Kerala State, southern India. It is characterized mainly by the presence of ten anterior prostomal teeth, absence of basal teeth, simple deirids, length of spicules, number and arrangement of preanal papillae and non-filamented eggs. Two species of camallanid nematodes, adults of Camallanus cotti Fujita, 1927 and a single Procamallanus (Spirocamallanus) sp. fourth-stage larva, were also recorded from A. bengalensis. Camallanus cotti, a pathogenic parasite of many species of wild and aquarium-reared fishes in many countries of South and East Asia, Europe, South and North America, West Indies and Australia, is reported for the first time from a representative of the fish family Anguillidae. Descriptions of R. (R.) keralaensis and Indian specimens of C. cotti, based on light and scanning electron microscopical examinations, are provided. Camallanus oxygasterae Gupta et Bakshi, 1983 is considered a junior synonym of C. cotti.
Utrastructural observations on Goussia metchnikovi (Laveran, 1897) in the spleen of gudgeon, Gobio gobio L.
Authors: Ball Stanley , Daszak Peter , Davies Angela 
Published: February 2012

AbstractThe ultrastructure of gamonts and sporulated oocysts of Goussia metchnikovi in the spleen of gudgeon, Gobio gobio from the river Lee, England is described. In developing microgamonts, small amylopectin granules were grouped centrally and nuclei were often arranged peripherally, close to the surface membrane. Nuclear chromatin condensed into peripheral dense portions that became the nuclei of flagellated microgametes, released to the parasitophorous vacuole. The cytoplasm of macrogametes had larger, scattered amylopectin granules, lipid globules and small electron-dense bodies, but no obvious wall forming bodies; peripheral vesicular structures with the appearance of mitochondria were also present and the parasitophorous vacuole contained flocculent material, but was otherwise free of structures. Sporulated oocysts contained four sporocysts and oocyst walls appeared to consist of a single membrane. Sporocyst walls showed a dehiscence suture, characteristic of the genus Goussia, which had filamentous extensions in places. The sporocyst wall comprised a dense inner layer and a thin outer layer with a fuzzy coat, separated by an electron lucent layer. Groups of oocysts were encapsulated by fibrous layers and inflammatory cells, and many sporocysts and their contained sporozoites showed evidence of elimination by the host.
First record of an arthropod from the Passaic Formation (Late Triassic), near Milford, New Jersey
Authors: Metz Robert 
Published: February 2012

AbstractMudstones of the Triassic Passaic Formation, near Milford, New Jersey, have yielded the first evidence of an arthropod impression in that formation. Associated trace fossils include Helminthoidichnites, Lockeia, Scoyenia, Spongeliomorpha, and the reptile footprint Rhynchosauroides, representing the Scoyenia ichnofacies. Associated sedimentary structures include desiccation cracks and raindrop impressions. The Passaic sediments were deposited under shallow water lacustrine shoreline conditions subject to periodic subaerial exposure.
Beans, baths and the barber... A sacred law from Thuburbos Maius
Authors: Kleijwegt Marc 
Published: February 2012

L'inscription II.Af. 225, provenant de Thuburbo Maius, est une loi sacrée datant du milieu du deuxième siècle après J.-C. Ses prescriptions concernent les visiteurs du temple d'Esculape. Ceux-ci doivent, pendant trois jours, s'abstenir de femmes, de fèves et de viande de porc, renoncer à se rendre chez le barbier ou aux bains publics et sont tenus de se déchausser pour entrer dans le temple. Le savant italien F. Vattioni, il y a une quinzaine d'années, avait tenté d'interpréter cette loi dans un contexte sémite / biblique, mais n'avait pas pu expliquer tous les articles mentionnés ni pour quelles raisons on les trouve dans une loi sacrée d'Esculape. Néanmoins, les mêmes prescriptions figurent dans l'ouvrage de Philostrate La vie d'Apollonius de Tyane, ce sage du premier siècle qui était un fervent disciple de Pythagore. En alléguant d'autres parallèles on peut affirmer que ces prescriptions s'accordent mieux avec un contexte gréco-oriental. A Thuburbo Maius un code de prescriptions adopté par les sages pour un usage permanent, a été subordonné pour les besoins du culte à une période réduite à trois jours, durée jugée nécessaire à l'incubation dans le temple d'Esculape.
L'incubation était certainement le but essentiel de cette loi, puisqu'on ne trouve mention d'aucune prescription de sacrifice. La pureté mentale, condition de rêves paisibles, était une exigence absolue pour entrer en contact avec le dieu : bonus intra, melior exi.
High‐throughput capture of nucleotide sequence polymorphisms in three Brassica species (Brassicaceae) using DNA microarrays
Authors: Nishizawa Toru , Tamaoki Masanori , Kaneko Yukio , Aono Mitsuko , Kubo Akihiro , Saji Hikaru , Nakajima Nobuyoshi 
Published: February 2012

• Premise of the study: To capture molecular markers that are applicable to environmental risk assessment of genetically modified oilseed rape, and to streamline their development, we screened variations in nucleotide sequences of three Brassica species by DNA microarray analysis.• Methods and Results: Using the Affymetrix GeneChip Arabidopsis ATH1 Genome Array, we monitored gene expression at 22810 loci among the Brassica species and picked out 192 putative polymorphic loci. We sequenced 25 of these and successfully aligned them among all three species. All 25 loci possessed some interspecific and at times intraspecific nucleotide variation.• Conclusions: DNA microarray analysis effectively detected a large number of nucleotide sequence variations among closely related Brassica species. The polymorphic regions will allow the subsequent development of functional gene markers.
Gardening as an Occupation: A Critical Review
Authors: York Michelle , Wiseman Tania 
Published: February 2012

Purpose: The occupation of gardening has historically generated a wealth of literature. Although espousing its positive impact on wellbeing, evidence is typically anecdotal in nature, with only one major synthesis of reliable evidence to date. This study sought to explore people's experiences and personal meanings of gardening within the literature, from 2003–2010, in order to present a concise body of evidence and to inform occupational therapy practice. Procedures: A meta-ethnography was used in gathering high quality qualitative studies, synthesising through a process of translations, rather than aggregation, in order to preserve meanings from within a range of culturally specific contexts. Four papers, out of 214 initially identified, met the inclusion criteria employed. Findings: This study has identified processes within the occupation of gardening in a natural environment, which offer satisfying and meaningful methods of recovery for people who are marginalised within society. This has been shown on an individual and a community health level. Conclusion: This study has highlighted fundamental links between gardening and wellbeing, and how occupational therapists can broaden practice and have an impact upon health at a community level.
A BOUNDARY-LAYER APPROACH TO STRESS ANALYSIS IN THE SIMPLE SHEARING OF RUBBER BLOCKS
Authors: Horgan Cornelius O. , Murphy Jeremiah G. 
Published: February 2012

Abstract
Rubbers are usually modeled as being perfectly incompressible. In the simple shear of rubber blocks, the normal stress components, therefore, contain an arbitrary constant pressure term to be determined from the boundary conditions. There is therefore a fundamental ambiguity in the determination of this pressure because the normal stresses are expected to be identically zero on different faces of the sheared block. It is proposed here that the stress distribution near a face should be determined by the normal stress boundary condition at that face and that this distribution is valid only within a short distance from the face, giving rise to boundary layers at the faces of the sheared block. At the intersection of these boundary layers it will be assumed that the stress is additive. It is further assumed that the stresses within the bulk of the material should be determined by treating the perfectly incompressible material as equivalent to a slightly compressible material. The form of slight compressibility adopted here is that usually assumed in the finite element simulation of rubbers. These reasonable assumptions give rise to a complex stress pattern within the block. The results are qualitatively similar to results obtained by other authors on using a finite element approach for a neo-Hookean material. The possible occurrence of cavitation at the corners of the block is also examined.
Pragmatics and Cognition
Authors: Ifantidou Elly 
Published: June 2024

Abstract

Language does not happen in a social vacuum. This idea lies at the origins of pragmatics forged by Austin and Searle's classical answers to how verbal communication is achieved. Language does not occur in a cognitive vacuum either. Thanks largely to the influential work of Paul Grice, modern pragmatics has recognized that verbal and nonverbal communication is an inferential activity involving the expression and recognition of
intentions
. These two factors—the social and the cognitive inherent in online processing—are reflected in natural behaviors and in speech coupled with gestures, voice, attitudes, desires, as well as emotions conveyed.

In principle, the aim of pragmatic theory is to explain how
utterances
—with all their linguistic and nonlinguistic properties—are understood. The advent of cognitive pragmatics in the early 1980s brought a different orientation: “pragmatics” is a capacity of the mind which interacts with the utterance comprehension system to show, or recognize, someone's intention to inform. But in the process of utterance interpretation, speakers show us more about their beliefs, desires, and intentions to convey their happiness, distress, anger, or fear, than the words they have used.
Technology in Language Teaching: Mixed‐Methods Research
Authors: Chen Yu‐Li 
Published: June 2024

Abstract
Currently, using technology for teaching is a challenge for language teachers, as seen in various studies on why and how teachers have approached the incorporation of technology into their instruction and the best practices. This entry offers an overview of the advantages of applying a mixed‐methods research design to explore how language teachers have adapted to the current, rapid technological advances. The study described in this entry used the quantitative method of a survey and qualitative technique of interviews. The survey data were analyzed using structural equation modeling and the interview responses using a thematic analysis. Finally, the two data analyses and results were combined and converged for comparison and corroboration and thus obtained a comprehensive understanding of the integration of technology into language teachers' instructive practices in northern Taiwan.
Four‐hour‐delayed 3D‐FLAIR MRIs in patients with acute unilateral peripheral vestibulopathy
Authors: Kim Keun‐Tae , Park Sangeun , Lee Sun‐Uk , Park Euyhyun , Kim Byungjun , Kim Byung‐Jo , Kim Ji‐Soo 
Published: June 2024

AbstractObjectiveConventionally, MRI aids in differentiating acute unilateral peripheral vestibulopathy/vestibular neuritis (AUPV/VN) from mimickers. Meanwhile, the diagnostic utility of MRIs dedicated to the inner ear remains to be elucidated for diagnosing AUPV/VN.MethodsWe prospectively recruited 53 patients with AUPV/VN (mean age ± SD = 60 ± 15 years, 29 men). Initial MRIs were performed with a standard protocol, and an additional axial 3D‐fluid‐attenuated inversion recovery (3D‐FLAIR) sequence was obtained 4 h after intravenous injection of gadoterate meglumine. Abnormal enhancement was defined as a signal intensity that exceeded the mean + 2SD value on the healthy side. The findings of neurotologic evaluation and MRIs were compared.ResultsOverall, the inter‐rater agreement for gadolinium enhancement was 0.886 (Cohen's kappa coefficient). Enhancement was observed in 26 patients (49%), most frequently in the vestibule (n = 20), followed by the anterior (n = 12), horizontal (HC, n = 8), posterior canal (n = 5), and superior (n = 3) and inferior (n = 1) vestibular nerves. In multivariable logistic regression analysis, the enhancement was associated with decreased HC gain in video head‐impulse tests (p = 0.036), increased interaural difference in ocular vestibular‐evoked myogenic potentials (p = 0.001), and a longer onset‐to‐MRI time span (p = 0.024). The sensitivity and specificity were 92.3% and 81.5%, respectively, with an area under the curve of 0.90 for predicting gadolinium enhancement.InterpretationRobust gadolinium enhancement was observed on 4‐hour‐delayed 3D‐FLAIR images in nearly half of the patients with AUPV/VN, with a good correlation with the results of neurotologic evaluation. The positivity may be determined by the extent of vestibular deficit, timing of imaging acquisition, and possibly by the underlying etiology causing AUPV/VN. MRIs may aid in delineating the involved structures in AUPV/VN.
A Water‐Insoluble Yttrium‐Based Complex as Dual‐Ionic Electrolyte Additive for Stable Aqueous Zinc Metal Batteries
Authors: Li Liansheng , Chen Chun , Meng Pengyu , Zhang Yijie , Liang Qinghua 
Published: June 2024

AbstractAqueous batteries employing Zinc metal anodes (ZMAs) are considered to be promising next‐generation energy storage systems. However, the severe interfacial side reactions and dendrite growth restrict the practical application of ZMAs in aqueous electrolytes. Herein, a water‐insoluble dual‐ionic electrolyte additive of yttrium 2,4,5‐trifluorophenylacetate (YTFPAA) is developed to stabilize the aqueous ZMAs. Notably, the ethanol‐solvated TFPAA− can capture H+ and thus buffer the decreased electrolyte pH caused by the hydrolysis of Y3+. Furthermore, the ethanol‐solvated TFPAA− can dynamically adsorb onto the surface of ZMAs through a reversible oxidation‐reduction reaction, effectively suppressing the interfacial side reactions by forming a water‐poor interface, and enhancing the reversibility of Zn2+ deposition/stripping by redistributing the Zn2+ flux. These favorable effects of TFPAA− combined with the dynamic electrostatic shielding effect of Y3+ ultimately enable uniform and dense Zn2+ deposition. As a result, the Zn/Zn cells assembled with 0.25YTFPAA electrolyte exhibit an impressive cycle life of 2100 h at 0.5 mA cm−2–0.25 mAh cm−2. More importantly, the assembled V2O5/Zn full cell shows an ultra‐long cycle life of up to 18000 cycles at 5.0 A g−1. This work highlights the rational design of multifunctional ionic additives for stabilizing aqueous ZMAs.
Palladium‐Catalyzed Carbonylative Transformation for the Synthesis of Tetracyclic Indoline Thioesters
Authors: Li Ming , Zhao Guo‐Xiao , Xu Shanmei , Miao Dong‐Yu , Li Shun‐Xi , Qiu Yi‐Feng , Chen Dong‐Ping , Quan Zheng‐Jun , Wang Xi‐Cun , Liang Yong‐Min 
Published: June 2024

AbstractPalladium‐catalyzed thioesterification of (aza)indole‐tethered aryl iodides, Mo(CO)6, and sulfonyl chlorides is reported. A series of C2 thioester‐group substituted indoline‐fused ring compounds are constructed by an intramolecular Heck cyclization and carbonylation chemistry involving N‐(2‐iodobenzoyl)indole. The salient features of this three‐component cascade sequence include the use of solid Mo(CO)6 as the carbon monoxide source and good functional group tolerance.
A Novel Ubiquitin Ligase Adaptor PTPRN Suppresses Seizure Susceptibility through Endocytosis of NaV1.2 Sodium Channels
Authors: Wang Yifan , Yang Hui , Li Na , Wang Lili , Guo Chang , Ma Weining , Liu Shiqi , Peng Chao , Chen Jiexin , Song Huifang , Chen Hedan , Ma Xinyue , Yi Jingyun , Lian Jingjing , Kong Weikaixin , Dong Jie , Tu Xinyu , Shah Mala , Tian Xin , Huang Zhuo 
Published: June 2024

AbstractIntrinsic plasticity, a fundamental process enabling neurons to modify their intrinsic properties, plays a crucial role in shaping neuronal input‐output function and is implicated in various neurological and psychiatric disorders. Despite its importance, the underlying molecular mechanisms of intrinsic plasticity remain poorly understood. In this study, a new ubiquitin ligase adaptor, protein tyrosine phosphatase receptor type N (PTPRN), is identified as a regulator of intrinsic neuronal excitability in the context of temporal lobe epilepsy. PTPRN recruits the NEDD4 Like E3 Ubiquitin Protein Ligase (NEDD4L) to NaV1.2 sodium channels, facilitating NEDD4L‐mediated ubiquitination, and endocytosis of NaV1.2. Knockout of PTPRN in hippocampal granule cells leads to augmented NaV1.2‐mediated sodium currents and higher intrinsic excitability, resulting in increased seizure susceptibility in transgenic mice. Conversely, adeno‐associated virus‐mediated delivery of PTPRN in the dentate gyrus region decreases intrinsic excitability and reduces seizure susceptibility. Moreover, the present findings indicate that PTPRN exerts a selective modulation effect on voltage‐gated sodium channels. Collectively, PTPRN plays a significant role in regulating intrinsic excitability and seizure susceptibility, suggesting a potential strategy for precise modulation of NaV1.2 channels' function.
CD147‐K148me2‐Driven Tumor Cell‐Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis
Authors: Wang Ke , Chen Xiaohong , Lin Peng , Wu Jiao , Huang Qiang , Chen Zhi‐Nan , Tian Jiale , Wang Hao , Tian Ye , Shi Mingyan , Qian Meirui , Hui Bengang , Zhu Yumeng , Li Ling , Yao Rui , Bian Huijie , Zhu Ping , Chen Ruo , Chen Liang 
Published: June 2024

AbstractImmunosuppression is a major hallmark of tumor progression in non‐small cell lung cancer (NSCLC). Cluster of differentiation 147 (CD147), an important pro‐tumorigenic factor, is closely linked to NSCLC immunosuppression. However, the role of CD147 di‐methylation in the immunosuppressive tumor microenvironment (TME) remains unclear. Here, di‐methylation of CD147 at Lys148 (CD147‐K148me2) is identified as a common post‐translational modification (PTM) in NSCLC that is significantly associated with unsatisfying survival outcomes among NSCLC sufferers, especially those in the advanced stages of the disease. The methyltransferase NSD2 catalyzes CD147 to generate CD147‐K148me2. Further analysis demonstrates that CD147‐K148me2 reestablishes the immunosuppressive TME and promotes NSCLC progression. Mechanistically, this modification promotes the interaction between cyclophilin A (CyPA) and CD147, and in turn, increases CCL5 gene transcription by activating p38‐ZBTB32 signaling, leading to increased NSCLC cell‐derived CCL5 secretion. Subsequently, CD147‐K148me2‐mediated CCL5 upregulation facilitates M2‐like tumor‐associated macrophage (TAM) infiltration in NSCLC tissues via CCL5/CCR5 axis‐dependent intercellular crosstalk between tumor cells and macrophages, which is inhibited by blocking CD147‐K148me2 with the targeted antibody 12C8. Overall, this study reveals the role of CD147‐K148me2‐driven intercellular crosstalk in the development of NSCLC immunosuppression, and provides a potential interventional strategy for PTM‐targeted NSCLC therapy.
A Bionic Flapping Magnetic‐Dipole Resonator for ELF Cross‐Medium Communication
Authors: Cheng Zhi , Zhou Jing , Wang Bin , Wu Qiong , Ma Liang , Qin Zhi , Shen Jie , Chen Wen , Peng Wei , Chang Jianglei , Ci Penghong , Dong Shuxiang 
Published: June 2024

AbstractExtremely low‐frequency (ELF) electromagnetic (EM) waves adeptly propagate in harsh cross‐medium environments, overcoming rapid decay that hinders high‐frequency counterparts. Traditional antennas, however, encounter challenges concerning size, efficiency, and power. Here, drawing inspiration from nature, we present a groundbreaking piezo‐actuated, bionic flapping‐wing magnetic‐dipole resonator (BFW‐MDR), operating in the electro‐mechano‐magnetic coupling mechanism, designed for efficient ELF EM wave transmission. The unique rigid‐flexible hybrid flapping‐wing structure magnifies rotation angles of anti‐phase magnetic dipoles by tenfold, leading to constructive superposition of emitted magnetic fields. Consequently, the BFW‐MDR exhibits a remarkable quality factor of 288 and an enhanced magnetic field emission of 514 fT at 100 meters with only 6.9 mW power consumption, surpassing traditional coil antennas by three orders of magnitude. The communication rate is doubled by the ASK+PSK modulation method. Its robust performance in cross‐medium communication, even amidst various interferences, underscores its potential as a highly efficient antenna for underwater and underground applications.