bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sequential Dissection for Exposure of the Second Metatarsophalangeal Joint
Authors: Cooper Minton Truitt , Coughlin Michael J. 
Published: April 2011

Background: Instability of the second metatarsophalangeal (MTP) joint is relatively common, and although the anatomy of the joint has been well described and plantar plate pathology has been identified, little has been written about its exposure and repair. The goal of this study was to elucidate the necessary dissection to expose and potentially repair the lesions of the plantar plate through a dorsal approach. Materials and Methods: Sequential dorsal dissection of the second MTP joint was carried out in eight cadaveric specimens. After each step, measurements were obtained using fluoroscopic imaging and digital photography to determine the amount of exposure of the plantar plate gained by each step. Results: Dorsal capsulotomy of the second MTP joint with collateral ligament release off of the proximal phalanx base, then combined with a subcapital oblique metatarsal osteotomy provided on average 8 and 8.5 mm of exposure of the plantar plate as measured by digital photography and fluoroscopy, respectively. Minimal exposure was gained by releasing the collateral ligaments from the metatarsal head or elevating the plantar plate off of the plantar metatarsal head. Conclusion: Exposure of the plantar plate can be obtained by releasing the collateral ligaments off of the proximal phalanx and performing a subcapital oblique osteotomy. Clinical Relevance: Minimizing the risk of disrupting the blood supply to the metatarsal head may be possible by avoiding collateral ligament or plantar plate release.
Stability of Locking and Non-Locking Plates in an Osteoporotic Calcaneal Fracture Model
Authors: Illert Till , Rammelt Stefan , Drewes Tim , Grass Rene , Zwipp Hans 
Published: April 2011

Background: The aim of this biomechanical cadaver study of calcaneal fractures was to investigate whether a locking calcaneal plate provides more stiffness in osteoporotic bone compared to a non-locking plate. Materials and Methods: Sixteen fresh frozen bone mineral density (BMD)-matched cadaver feet were tested in a four-part model of a Sanders Type IIB calcaneal fracture. The fractures were fixed either with a non-locking AO (Sanders) plate or an interlocking AO plate (Synthes, Paoli, PA) to the lateral calcaneal wall with six screws. Specimens were subjected to cyclic loading which was increased stepwise to full body weight. Displacement of the posterior facet fragment was measured with an optical tracking system in the sagittal and transverse planes. Results: No statistically significant differences were observed between the non-locking and the locking plates with respect to number of cycles to failure or 1-mm displacement of the posterior facet. The initial stiffness was significantly higher for non-locking plates. Conclusion: In osteoporotic bone, the greater stiffness of the screw-locking-plate construct was offset by the smaller diameter of the screw threads and the lower friction between the plate and bone when a locking plate was used. In clinical practice, the plate should first be compressed to osteoporotic bone with cancellous screws and at least two screws should be placed in the anterior process and in the tuberosity of the calcaneus.
Hidden in Music: Religious Experience and Pop Festivals
Authors: Kommers Heleen 
Published: April 2011

Abstract: Can pop festivals offer young people opportunities to experience transcendental ideas, resulting in religiosity? The research proposed in this article joins current debates about pop music as a substitute for institutional forms of religion which are supposed to be vanishing. This article offers a critical reflection on some well-established approaches like large-scale quantitative studies and those focusing on cultural change. It contains a plea for qualitative research: so-called multi-sited fieldwork, stressing participant observation. The article is of a programmatic, reflective character. The research starts from the perspective of young people, following the Malinowskian dictum: to discover their vision of their world.
Doomsday America: The Pessimistic Turn of Post-9/11 Apocalyptic Cinema
Authors: Walliss John , Aston James 
Published: April 2011

Abstract: In this article we discuss the cycle of apocalypse films released in the aftermath of the attacks of 11 September 2001, examining the ways in which they conveyed a variety of post-9/11 fears and concerns around issues such as the War on Terror, American imperialism and the environment. In particular, we will trace the continuities and discontinuities with similar disaster/apocalyptic films released in the late 1990s, tracking the representations of four thematic elements that permeate through both pre-millennium and post-9/11 apocalyptic Hollywood cinema: the representation of the apocalypse; the role of human agency as saviour; the role of religion; and socio-political commentary made by the films. In doing so, we argue that cinematic representations of the apocalypse have been much more pessimistic post-9/11, thus demonstrating that Hollywood science fiction, or “sci-fi,” can facilitate wider socio-political concerns while continuing to provide the expected spectacular, audio-visual displays.
Ökosponsoring – mehr als eine neue Einnahmequelle? | Environmental sponsorship – more than a source of revenue?
Authors: Schoop Georg , Niedermann-Meier Sarah 
Published: April 2011

With the current emphasis on the term “sustainable development” in society and politics, it is becoming more and more important and economically effective for a business to seek public recognition through its ecological and social services. This can be seen in the increased significance of environmental sponsorship. This is one method of marketing and financing an environmental project. With the financial contribution from sponsors, income can be generated and measures carried out which with the normal budget could not have been taken into consideration. However, environmental sponsorship goes a lot further than the provision of funds for an environmental service. A service bundle is marketed, which includes for example contractual rights for advertising, appearances in the media, the organisation of events or other exclusive rights for the sponsor. Through these a great benefit arises for all the partners involved.
Since 1997 the City Forestry Service of Baden has carried out a number of successful environmental sponsorship projects. Altogether about 850 000 Swiss francs were collected which could be invested in nature and educational projects. This represents about 3–6% of the total turnover. Above all, experience shows that the new contacts established with commerce and society through the sponsoring projects are of great value. Through the additional activities of the sponsors within the framework of their project, such as events for customers, the distribution of brochures and advertising, they succeeded in making people attentive to the importance of forests and nature, who up until then had hardly addressed the issue, but were often employed in influential jobs in the economy, in society or in cultural activities.
Agricultures capitalistes et paysannes dans l'État de Bahia au Brésil
Authors: da Silva Gomes Andréa , Bittencourt M.G. , Dufumier M. 
Published: April 2011

Du fait de l’abondance relative de ses terrains arables et pâturables, le Brésil est devenu un grand pays exportateur de café, sucre et éthanol, huiles et tourteaux de soja, viandes diverses, agrumes, etc. Mais le Brésil rural continue néanmoins encore de souffrir de l’inégale répartition des terres agricoles comme en témoigne la situation économique dans les régions d’Itajuípe - Coaraci et de Valente (État de Bahia). La mise en œuvre de la réforme agraire au Brésil ne devrait pas donc être envisagée exclusivement pour des raisons de justice sociale mais aussi pour des raisons économiques.
Animaux symboliques, animaux interpsychiques
Authors: Bolognini Stefano 
Published: April 2011

Résumé À travers une brève présentation de deux histoires cliniques, l’auteur décrit certaines dimensions symboliques et interpsychiques que l’apparition d’animaux sur la scène analytique évoque et stimule aussi parfois. L’auteur explore également les analogies fonctionnelles possibles entre la coopération élémentaire homme/chien et la coopération analytique au niveau du travail de base, et la métaphore de la « chatière » comme modèle d’une communication fluide entre préconscient et conscient dans un régime économique de facilitation et d’économie d’énergie intrapsychique.
De l'animal numérique au robot de compagnie : quel avenir pour l'intersubjectivité ?
Authors: Tisseron Serge 
Published: April 2011

Résumé Les relations que nous entretenons avec les animaux virtuels de nos écrans préfigurent indiscutablement celles que nous auronts demain avec les robots de compagnie. Mais il existe une grande différence entre nos relations avec les animaux réels et les animaux virtuels ou, bientôt, les robots. Nous pouvons, à la rigueur, nous imaginer à la place d’un animal – et les enfants autistes y réussissent même bien –, mais il nous est difficile de penser que nous puissions nous mettre à la place d’un robot. Pourtant, c’est bel et bien le rêve de certains de ceux qui les construisent…
Morgue, fée de cour ? La féerie courtoise dans le Livre des Visions d'Oger le Dannoys au royaulme de Fairie de François Habert
Authors: Hoernel Alexandra 
Published: April 2011

a courtly fairy? The courtly fairy world in the Livre des visions d’Oger le Dannoys au royaulme de Fairie by François Habert Even though fairies do not naturally mix with humans, at the end of the Middle Ages, the world of fairies and that of the court (and of courtoisie ) seem to come together in reciprocal assimilation. From a study of the rewriting of the legend of Ogier the Dane by François Habert in 1542, this article shows that the phenomenon results from two kinds of writing. On the one hand, there is a process of ritualization, which is produced by a spectacular tale integrating the fairy world into a collective ceremonial orchestrated in the real world just as in the fictional one On the other, a degree of rationalization integrates the figures of the fairy world either by turning them into exemplars (as models of courtly relations) or by attributing allegorical value to them (as figures of Fortune). This mix of realistic and magical features then becomes characteristic of a synthesis that materializes, through the image of Morgana, into a fantasy of courtly fairydom.
Dopamine D1-Like Receptor Antagonist Attenuates Th17-Mediated Immune Response and Ovalbumin Antigen-Induced Neutrophilic Airway Inflammation
Authors: Nakagome Kazuyuki , Imamura Mitsuru , Okada Hirokazu , Kawahata Kimito , Inoue Tsutomu , Hashimoto Kumiko , Harada Hiroaki , Higashi Takehiro , Takagi Rie , Nakano Kazuhisa , Hagiwara Koichi , Kanazawa Minoru , Dohi Makoto , Nagata Makoto , Matsushita Sho 
Published: April 2011

Abstract
Allergic airway inflammation is generally considered a Th2-type immune response. Recent studies, however, demonstrated that Th17-type immune responses also play important roles in this process, especially in the pathogenesis of neutrophilic airway inflammation, a hallmark of severe asthma. We previously reported that dendritic cells release dopamine to naive CD4+ T cells in Ag-specific cell–cell interaction, in turn inducing Th17 differentiation through dopamine D1-like receptor (D1-like-R). D1-like-R antagonist attenuates Th17-mediated diseases such as experimental autoimmune encephalomyelitis and autoimmune diabetes. However, the effect of antagonizing D1-like-R on Th17-mediated airway inflammation has yet to be studied. In this study, we examined whether D1-like-R antagonist suppresses OVA-induced neutrophilic airway inflammation in OVA TCR-transgenic DO11.10 mice and then elucidated the mechanism of action. DO11.10 mice were nebulized with OVA or PBS, and some mice received D1-like-R antagonist orally before OVA nebulization. D1-like-R antagonist significantly suppressed OVA-induced neutrophilic airway inflammation in DO11.10 mice. It also inhibited the production of IL-17 and infiltration of Th17 cells in the lung. Further, D1-like-R antagonist suppressed the production of IL-23 by lung CD11c+ APCs. In contrast, D1-like-R antagonist did not increase Foxp3+ regulatory T cells in the lung. D1-like-R antagonist neither suppressed nonspecific LPS-induced neutrophilic airway inflammation nor OVA-induced eosinophilic airway inflammation. These results indicate that D1-like-R antagonist could suppress Th17-mediated neutrophilic airway inflammation, raising the possibility that antagonizing D1-like-R serves as a promising new strategy for treating neutrophil-dominant severe asthma.
Caspase-1–Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity
Authors: Lalor Stephen J. , Dungan Lara S. , Sutton Caroline E. , Basdeo Sharee A. , Fletcher Jean M. , Mills Kingston H. G. 
Published: April 2011

Abstract
IL-1β plays a critical role in promoting IL-17 production by γδ and CD4 T cells. However, IL-1–targeted drugs, although effective against autoinflammatory diseases, are less effective against autoimmune diseases. Conversely, gain-of-function mutations in the NLRP3 inflammasome complex are associated with enhanced IL-1β and IL-18 production and Th17 responses. In this study, we examined the role of caspase-1–processed cytokines in IL-17 production and in induction of experimental autoimmune encephalomyelitis (EAE). Killed Mycobacterium tuberculosis, the immunostimulatory component in CFA used for inducing EAE, stimulated IL-1β and IL-18 production by dendritic cells through activation of the inflammasome complex and caspase-1. Dendritic cells stimulated with M. tuberculosis and myelin oligodendrocyte glycoprotein promoted IL-17 production by T cells and induced EAE following transfer to naive mice, and this was suppressed by a caspase-1 inhibitor and reversed by administration of IL-1β or IL-18. Direct injection of the caspase-1 inhibitor suppressed IL-17 production by CD4 T cells and γδ T cells in vivo and attenuated the clinical signs of EAE. γδ T cells expressed high levels of IL-18R and the combination of IL-18 and IL-23, as with IL-1β and IL-23, stimulated IL-17 production by γδ T cells, but also from CD4 T cells, in the absence of TCR engagement. Our findings demonstrate that caspase-1–processed cytokines IL-1β and IL-18 not only promote autoimmunity by stimulating innate IL-17 production by T cells but also reveal redundancy in the functions of IL-1β and IL-18, suggesting that caspase-1 or the inflammasome may be an important drug target for autoimmune diseases.
Noncanonical K27-Linked Polyubiquitination of TIEG1 Regulates Foxp3 Expression and Tumor Growth
Authors: Peng Dong-Jun , Zeng Minghui , Muromoto Ryuta , Matsuda Tadashi , Shimoda Kazuya , Subramaniam Malayannan , Spelsberg Thomas C. , Wei Wei-Zen , Venuprasad K. 
Published: April 2011

Abstract
Earlier, we demonstrated the essential role of Kruppel-like transcription factor, TIEG1, in TGF-β–induced regulatory T cell (Treg) development. In this article, we demonstrate that IL-6, which promotes Th17 development, abrogated TIEG1 nuclear translocation and inhibited TGF-β–induced Treg development. Tyrosine kinase Tyk2-mediated phosphorylation of TIEG1 at Tyr179 promoted noncanonical K-27–linked polyubiquitination, which inhibited TIEG1 nuclear translocation. To test the role of TIEG1-regulated Treg/Th17 development in antitumor immunity, we analyzed TRAMP-C2 tumor growth in TIEG1−/− mice. The defective Treg development and elevated Th17 response resulted in enhanced immune reactivity in the tumor and inhibition of TRAMP-C2 tumor growth in TIEG1−/− mice. Thus, our results uncovered a novel regulatory mechanism that modulates Tregs and may regulate tumor progression.
Cost-Effectiveness Analysis of Unicompartmental Knee Arthroplasty and High Tibial Osteotomy for Treatment of Medial Compartmental Osteoarthritis
Authors: Brown Christopher A , Watters Tyler S , Mather Richard C , Orlando Lori A 
Published: April 2011

ABSTRACT

Background
Interest in unicompartmental knee arthroplasty (UKA) has recently increased in the United States concomitantly with an increase in the prevalence of physiologically active patients presenting with medial compartment osteoarthritis. This study examined the cost-effectiveness of UKA compared with high tibial osteotomy (HTO) in patients with medial compartment osteoarthritis.

Methods
A Markov decision model was constructed with review of literature to conduct a cost-utility analysis of UKA as compared to HTO in a patient population aged 40 years at the time of surgical intervention. Utility values were assigned to health states annually based on the commonly accepted reference values of 1 being “full health” and 0 being “death”. These values are used to estimate quality-adjusted life years (QALYs). The Markov decision model was used to evaluate the total accumulated costs and effectiveness, measured in QALYs.

Results
The average cost of the UKA was cheaper by $842 and resulted in a significant incremental effectiveness gain compared to HTO (+ 0.96 QALY). UKA gained 20.05 QALY at a cost-effectiveness (C/E) ratio of $1048/QALY, whereas HTO gained 19.09 QALY at a C/E ratio of $1145/QALY.

Conclusion
Both UKA and HTO are cost-effective procedures but patients treated with UKA may experience an increased net health benefit over their lifetime.

Level of evidence
Economic and decision analysis level II.
Are there gender-related influences on corporate sustainability? A study of women on boards of directors
Authors: Galbreath Jeremy 
Published: April 2011

AbstractThis study sought to investigate if there is a link between women on boards of directors and corporate sustainability. Using a sample of publicly listed firms from Australia, the results suggest some level of support that a link does exist. Boards that have a strong complement of gender diversity are expected to offer more effective monitoring of agents, as well as offer more stringent enforcement of ethical conduct, thereby minimizing affects of subversion of shareholder funds that can be detrimental to their returns. Accordingly, findings confirm a positive link between women on boards and economic growth. Because of their relational abilities, women on boards are more likely able to engage with multiple stakeholders and respond to their needs, resulting in an avenue for demonstrating social responsiveness, which is confirmed by the results. However, due to their backgrounds and work experiences, sex-based biases and stereotyping might exist in boardrooms with men directors discounting input from women directors on issues relating to environmental quality. The results of this study find that women directors are not significantly associated with environmental quality. Discussion is given to these findings along with paths for future research.
Self-efficacy and effort in new venture development
Authors: Trevelyan Rose 
Published: April 2011

AbstractThere is a lot of evidence to suggest that entrepreneurial self-efficacy influences intentions and performance, but little research on ESE and actual activities. In this paper the possible dual impact of ESE on task effort is explored. On the one hand self-efficacy boosts motivation and persistence, but on the other hand high confidence in one's abilities can lead to decision-making shortcuts and reduced effort on key tasks (the overconfidence hypothesis). Propositions about the relationship between self-efficacy and effort on different types of tasks (action and judgment tasks) are developed and tested with a small sample of active entrepreneurs. Results support a positive impact of self-efficacy on effort regardless of the type of task, thereby raising questions about the overconfidence hypothesis. Understanding types of confidence (in one's ability, knowledge, and judgment) and effort (cognitive effort) may explain these results. Further research on these topics, and on entrepreneurial experience and the use of heuristics are suggested.
Multilevel absorptive capacity and interorganizational new product development: A process study
Authors: Newey Lance , Verreynne Martie-Louise 
Published: April 2011

AbstractThe objective of this paper is to deepen our understanding of the role of absorptive capacity in enabling interorganizational new product development (INPD). We contend that despite what is known about the benefits of absorptive capacity to innovating firms, this research is dominated by firm-level analyses using cross-sectional data. The accumulated knowledge about absorptive capacity thus does not help with understanding how absorptive capacity unfolds as a process within and between firms such as when firms collaborate in new product development. Using a longitudinal case study, we build new theory at the INPD system level of analysis that leads us to shed new light on the cross-level interactions between firm- and alliance-level absorptive capacities.
From the shadows into the light: Let's get real about outsourcing
Authors: Hunter James D , Hall Allastair N 
Published: April 2011

AbstractDespite the continued popularity of outsourcing amongst managers and management researchers alike, signifi cant questions arguably remain as to the adequacy of the typical framing of the outsourcing decision. An extensive review of the literature revealed a skewed, partial and fragmented conceptualisation of the option, further exacerbated by a concerning tendency effectively to rank quantitative outcomes over qualitative outcomes, even ex post. In this article it is argued that a critical analysis of the theoretical frameworks that underlie this body of work suggests a more realistic conceptualisation of outsourcing, both for management researchers and management decision makers.
More similar than different: A study of cooperative product innovation with multiple external stakeholders
Authors: von der Heidt Tania , Scott Don 
Published: April 2011

AbstractThis paper uses a strategy—structure—performance-based model of marketing channel relationship structure to conduct an empirical examination of the involvement of four external stakeholder groups in manufacturing firms' product innovation. The results show that firms' stakeholder orientation (strategy), involvement of stakeholders in product innovation (structure) and quality of stakeholder relationships (performance) are intrinsically linked. Also, the way in which multiple stakeholder groups were involved in manufacturing firms' product innovation was more similar than different.
Onboarding externally hired executives: Avoiding derailment – accelerating contribution
Authors: Guangrong Dai  , De Meuse Kenneth P , Gaeddert Dee 
Published: April 2011

AbstractExecutive onboarding has become a popular technique in the business world during the past decade. However, the demonstrated success of traditional onboarding practices is mixed. We assert in this article that executive onboarding should be strategic, so that it not only prevents executive derailment, but accelerates contribution to optimize strategic achievement. We review the literature and identify six problematic areas externally hired executives often encounter when transitioning in to new organizations. It is recommended that effective onboarding should be tailored to the targeted organizations and executives to address specific transition issues. We propose a conceptual framework to implement onboarding on a strategic basis. It is hoped that such a review and conceptual discussion will enhance the effectiveness of onboarding experiences and increase the likelihood of success for executives hired from outside the organization.