bluuebunny/crossref_metadata_2025_split huggingface dataset:
Usability evaluation of a glove-type wearable device for efficient biometric collection during triage
Authors: Shinozaki Masayoshi , Saito Daiki , Tomita Keisuke , Nakada Taka-aki , Nomura Yukihiro , Nakaguchi Toshiya 
Published: April 2024

AbstractTo efficiently allocate medical resources at disaster sites, medical workers perform triage to prioritize medical treatments based on the severity of the wounded or sick. In such instances, evaluators often assess the severity status of the wounded or sick quickly, but their measurements are qualitative and rely on experience. Therefore, we developed a wearable device called Medic Hand in this study to extend the functionality of a medical worker’s hand so as to measure multiple biometric indicators simultaneously without increasing the number of medical devices to be carried. Medic Hand was developed to quantitatively and efficiently evaluate "perfusion" during triage. Speed is essential during triage at disaster sites, where time and effort are often spared to attach medical devices to patients, so the use of Medic Hand as a biometric measurement device is more efficient for collecting biometric information. For Medic Hand to be handy during disasters, it is essential to understand and improve upon factors that facilitate its public acceptance. To this end, this paper reports on the usability evaluation of Medic Hand through a questionnaire survey of nonmedical workers.
Selective hydrogenolysis of furfural to 1,2-pentanediol over a Pt–Fe/MT catalyst under mild conditions
Authors: Cao Chen , Guan Weixiang , Liu Qiaoyun , Li Lin , Su Yang , Liu Fei , Wang Aiqin , Zhang Tao 
Published: April 2024

A Pt–Fe bimetallic catalyst is developed to produce 1,2-pentanediol from furfural under mild conditions of 140 °C and 0.1 MPa H2, affording by far the highest production rate.
Relationship Between Serum Brain-Derived Neurotrophic Factor and Neurotrophin-3 Levels and Hearing Thresholds in Patients With Age-Related Hearing Loss
Authors: Altay Diler Us , Korkmaz Hakan , Korkmaz Mukadder , Noyan Tevfik 
Published: April 2024

Background:
Age-related hearing loss (ARHL) is a general term used to describe the sensorineural type of hearing loss occurring in both ears in older adults. Neurotrophins are the most promising candidates for supporting the auditory nerve by increasing neuronal survival. This study aimed to help elucidate the pathophysiology of ARHL by determining whether any relationship exists between brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) levels in serum samples from patients diagnosed with ARHL.

Materials and Method:
Seventy-seven individuals, a study group of 41 patients diagnosed with ARHL, and a control group of 36 participants without hearing loss were evaluated. Serum samples were collected and used to measure serum BDNF and NT-3 levels with the new Nepenthe enzyme-linked immunosorbent assay method.

Results:

Median pure-tone average results in the 2000, 4000, and 6000 Hz ranges were 52.5 (44.3–67.3) dB HL in the ARHL group and 13.5 (11.1–17.1) dB HL in the control group. The difference was statistically significant (
p
= .001). Although NT-3 and BDNF levels were both lower in ARHL patients than in participants without hearing loss, only the BDNF levels were significantly (
p
= .002) lower. Mean left and right ear word recognition scores were also lower in ARHL patients than in control groups. The ARHL group was further divided into two subgroups based on word recognition scores to evaluate significant differences in BDNF and NT-3 levels. No statistically significant difference was observed in BDNF and NT-3 levels between these subgroups. However, there was a significant difference in word recognition scores.

Conclusions:
Low BDNF levels in the ARHL group suggest that BDNF may play a role in the pathogenesis of ARHL. Patients with low (ARHL1) and high (ARHL2) word recognition scores were compared for the first time in the literature in terms of BDNF and NT-3 levels. However, the results were not statistically significant. This article is a preliminary study and was written to provide guidance for our next comprehensive project.
Screening for Bacterial Vaginosis Prior to Delivery: A Cost–Effectiveness Study
Authors: Knochenhauer Hope E. , Lim Stephanie L. , Havrilesky Laura J. , Dotters-Katz Sarah K. 
Published: April 2024

Objective The objective of this study was to compare the cost and effectiveness of three strategies for screening and/or treating bacterial vaginosis (BV) during pregnancy prior to delivery: (1) the current standard of care was neither test nor treat for BV (Treat None); (2) test all patients for BV at 36 weeks' gestation; treat if positive (Test Treat); and (3) treat all patients undergoing cesarean delivery with intravenous metronidazole at time of surgery (Treat All Cesarean). Effectiveness was defined as avoidance of postpartum surgical site infection (SSI).
Study Design A decision analytic cost–effectiveness model was designed from a third-party payer perspective using clinical and cost estimates obtained from the literature, American College of Surgeons National Surgical Quality Improvement Program participant use file (2005–2019), 2019 National Vital Statistics, Medicare costs, and wholesale drug costs. Cost estimates were inflated to 2020 U.S. dollars. For this study, effectiveness was defined as avoidance of postpartum SSIs.
Results The base case analysis that is the current standard of care of not routinely testing and treating patients for BV (Treat None) was the most expensive and least effective strategy, with a mean cost of $59.16 and infection rate of 3.71%. Empirically treating all patients for BV without testing (Treat All Cesarean) was the most effective and the least expensive strategy, with a mean cost of $53.50 and an infection rate of 2.75%. Testing all patients for BV and treating those positive for BV (Test Treat) was also relatively inexpensive and effective, with an infection rate of 2.94% and mean cost of $57.05. Compared with Treat None, we would expect the Treat All Cesarean strategy to reduce the infection rate by 26%.
Conclusion These findings suggest that treating pregnant patients with intravenous metronidazole at time of cesarean delivery could be an effective and cost-saving strategy. Testing and treating for BV could also be considered a reasonable strategy, as it has the added benefit of preserving antibiotic stewardship. In no analysis was the standard of care strategy of neither testing nor treating for BV before delivery the preferred strategy.
Key Points
Solid-State Mechanochemical Clemmensen Reduction
Authors: Bhattacharjee Debjyoti , Jana Sayan K. , Maji Biplab 
Published: April 2024

AbstractMechanochemical synthesis has emerged as a sustainable alternative to traditional organic reactions, offering several advantages, including reduced solvent usage, lower reaction time, lower energy consumption, and enhanced reaction efficiency. In this study, the application of mechanochemistry to Clemmensen reduction, a classic method for converting aldehydes and ketones into alkanes, was explored. By employing ball milling as a mechanical activation, the feasibility and efficacy of mechanochemical Clemmensen reduction in various substrates were demonstrated. The results indicate that this approach offers comparable or improved yields and functional group compatibility compared to conventional methods while minimizing environmental impact. The reaction optimization strategies and scope of substrates are discussed, highlighting the potential of mechanochemical synthesis for sustainable organic transformations.
Evaluation of Quality of Life After Use the Virtual Reality in Patients with Neurodegenerative Disease
Authors: Malisky Jéssica Spricigo , Cavalcante-Leão Bianca Lopes , Severiano Maria Izabel , dos Santos Geslaine Janaina Bueno , Teive Hélio Augusto Guizoni , José Maria Renata , de Araújo Cristiano Miranda , Zeigelboim Bianca Simone 
Published: April 2024

Abstract
Introduction Spinocerebellar ataxias (SCAs) are a heterogeneous group of neurodegenerative diseases.
Objective To evaluate the living standard of patients with SCA, by applying the Vestibular Disorders Activities of Daily Living Scale (VADL) and Activitiesspecific Balance Confidence Scale (ABC) questionnaires.
Methods An uncontrolled clinical trial study was conducted with 28 patients who underwent anamnesis, ENT evaluation, and vestibular assessment and the application of questionnaires VADL and ABC before and after rehabilitation with virtual reality.
Results The vestibular exam was altered in 64.3% of the cases. The result between the correlation of the VADL and ABC questionnaires showed significant results in all cases (p < 0.005). The correlation between the ages and disease length with the VADL and ABC questionnaires was significant in the T3 assessment (p = 0.015). The correlation between the disease length and the VADL questionnaire was significant in all cases (p < 0.005). The comparison of the vestibular rehabilitation result (T1 to T2) showed a significant difference for all the applied games, except for the ski slalom. The comparison of the vestibular rehabilitation result (T1 to T3) showed significant difference for all the applied games (p < 0.005) (1st assessment before the start of rehabilitation designated T1, after 10 rehabilitation sessions, considered T2 and, at the end of 20 rehabilitation sessions, called T3).
Conclusion We can point out a direct improvement in the living standard, reflected by the reduction of falls, better balance, and march, contributing to a higher self-confidence in patients in daily activities.
Limb Ischemic Necrosis Secondary to Microvascular Thrombosis: A Brief Historical Review
Authors: Warkentin Theodore E. 
Published: April 2024

AbstractIschemic limb injury can be broadly classified into arterial (absent pulses) and venous/microvascular (detectable pulses); the latter can be divided into two overlapping disorders—venous limb gangrene (VLG) and symmetrical peripheral gangrene (SPG). Both VLG and SPG feature predominant acral (distal) extremity ischemic necrosis, although in some instances, concomitant nonacral ischemia/skin necrosis occurs. Historically, for coagulopathic disorders with prominent nonacral ischemic necrosis, clinician-scientists implicated depletion of natural anticoagulants, especially involving the protein C (PC) system. This historical review traces the recognition of natural anticoagulant depletion as a key feature of nonacral ischemic syndromes, such as classic warfarin-induced skin necrosis, neonatal purpura fulminans (PF), and meningococcemia-associated PF. However, only after several decades was it recognized that natural anticoagulant depletion is also a key feature of predominantly acral ischemic microthrombosis syndromes—VLG and SPG—even when accompanying nonacral thrombosis is not present. These acquired acral limb ischemic syndromes typically involve the triad of (a) disseminated intravascular coagulation, (b) natural anticoagulant depletion, and (c) a localizing explanation for microthrombosis occurring in one or more limbs, either deep vein thrombosis (helping to explain VLG) or circulatory shock (helping to explain SPG). In most cases of VLG or SPG there are one or more events that exacerbate natural anticoagulant depletion, such as warfarin therapy (e.g., warfarin-associated VLG complicating heparin-induced thrombocytopenia or cancer hypercoagulability) or acute ischemic hepatitis (“shock liver”) as a proximate factor predisposing to severe depletion of hepatically synthesized natural anticoagulants (PC, antithrombin) in the setting of circulatory shock.
Quantitative Analysis of the Supraorbital, Transorbital Microscopic, and Transorbital Neuroendoscopic Approaches to the Anterior Skull Base and Paramedian Vasculature
Authors: Houlihan Lena Mary , Loymak Thanapong , Abramov Irakliy , Jubran Jubran H. , Staudinger Knoll Ann J. , O'Sullivan Michael G. J. , Lawton Michael T. , Preul Mark C. 
Published: April 2024

Abstract
Objectives Our objective was to compare transorbital neuroendoscopic surgery (TONES) with open craniotomy and analyze the effect of visualization technology on surgical freedom.
Design Anatomic dissections included supraorbital craniotomy (SOC), transorbital microscopic surgery (TMS), and TONES.
Setting The study was performed in a neurosurgical anatomy laboratory.
Participants Neurosurgeons dissecting cadaveric specimens were included in the study.
Main Outcome Measures Morphometric analysis of cranial nerve (CN) accessible lengths, frontal lobe base area of exposure, and craniocaudal and mediolateral angle of attack and volume of surgical freedom (VSF) of the paraclinoid internal carotid artery (ICA), terminal ICA, and anterior communicating artery (ACoA).
Results The mean (standard deviation [SD]) frontal lobe base parenchymal exposures for SOC, TMS, and TONES were 955.4 (261.7) mm2, 846.2 (249.9) mm2, and 944.7 (158.8) mm2, respectively. Access to distal vasculature was hindered when using TMS and TONES. Multivariate analysis estimated that accessing the paraclinoid ICA with SOC would provide an 11.2- mm3 increase in normalized volume (NV) compared with transorbital corridors (p < 0.001). There was no difference between the three approaches for ipsilateral terminal ICA VSF (p = 0.71). Compared with TONES, TMS provided more access to the terminal ICA. For the ACoA, SOC produced the greatest access corridor maneuverability (mean [SD] NV: 15.6 [5.6] mm3 for SOC, 13.7 [4.4] mm3 for TMS, and 7.2 [3.5] mm3 for TONES; p = 0.01).
Conclusion SOC provides superior surgical freedom for targets that require more lateral maneuverability, but the transorbital corridor is an option for accessing the frontal lobe base and terminal ICA. Instrument freedom differs quantifiably between the microscope and endoscope. A combined visualization strategy is optimal for the transorbital corridor.
Three-phase equilibria of hydrates from computer simulation. II. Finite-size effects in the carbon dioxide hydrate
Authors: Algaba J. , Blazquez S. , Feria E. , Míguez J. M. , Conde M. M. , Blas F. J. 
Published: April 2024

In this work, the effects of finite size on the determination of the three-phase coexistence temperature (T3) of the carbon dioxide (CO2) hydrate have been studied by molecular dynamic simulations and using the direct coexistence technique. According to this technique, the three phases involved (hydrate–aqueous solution–liquid CO2) are placed together in the same simulation box. By varying the number of molecules of each phase, it is possible to analyze the effect of simulation size and stoichiometry on the T3 determination. In this work, we have determined the T3 value at 8 different pressures (from 100 to 6000 bar) and using 6 different simulation boxes with different numbers of molecules and sizes. In two of these configurations, the ratio of the number of water and CO2 molecules in the aqueous solution and the liquid CO2 phase is the same as in the hydrate (stoichiometric configuration). In both stoichiometric configurations, the formation of a liquid drop of CO2 in the aqueous phase is observed. This drop, which has a cylindrical geometry, increases the amount of CO2 available in the aqueous solution and can in some cases lead to the crystallization of the hydrate at temperatures above T3, overestimating the T3 value obtained from direct coexistence simulations. The simulation results obtained for the CO2 hydrate confirm the sensitivity of T3 depending on the size and composition of the system, explaining the discrepancies observed in the original work by Míguez et al. [J. Chem Phys. 142, 124505 (2015)]. Non-stoichiometric configurations with larger unit cells show a convergence of T3 values, suggesting that finite-size effects for these system sizes, regardless of drop formation, can be safely neglected. The results obtained in this work highlight that the choice of a correct initial configuration is essential to accurately estimate the three-phase coexistence temperature of hydrates by direct coexistence simulations.
Dual-functional pentamode metamaterial with water-like and topological transmission properties
Authors: Chu Yangyang , Hu Yuan , Wang Guanxi , Wang Zhaohong 
Published: April 2024

Abstract
In this paper, a water-like pentamode metamaterial (PM) with a single metallic material is designed and the topological edge-state transmission properties of elastic waves in the PM are thoroughly investigated. Numerical results indicate that by introducing structural perturbation into PM, the Dirac point degeneracy at K-point can be opened and topological band inversion can be generated. Topological edge states are also obtained by organizing PM structural units, which are robust to defects such as bending and cavities. In addition, it also has the mimics water in acoustic properties over a wide frequency range, i.e. it exhibits transparency when surrounded by water. Therefore, it will have both good transmission efficiency and acoustic stealth performance when used as an underwater waveguide. The dual-functional PM proposed in this study provides theoretical guidance for designing underwater stealth acoustic waveguides.
Free energy of a two-liquid system of charge carriers in strongly coupled electron and phonon fields and common nature of three phases in hole-doped cuprates
Authors: Myasnikova A E , Doronkina S V , Arutyunyan R R , Dzhantemirov A H 
Published: April 2024

Abstract
Hole-doped cuprates exhibit partially coexisting pseudogap (PG), charge ordering (CO) and superconductivity; we show that there exists a class of systems in which they have a single nature as it has recently been supposed. Since the charge-ordered phase exhibits large frozen deformation of the lattice, we develop a method for calculating the phase diagram of a system with strong long-range (Fröhlich) electron–phonon interaction. Using a variational approach, we calculate the free energy of a two-liquid system of carriers with cuprate-like dispersion comprising a liquid of autolocalized carriers (large polarons and bipolarons) and Fermi liquid of delocalized carriers. Comparing it with the free energy of pure Fermi liquid and calculating (with standard methods of Bose liquid theory) a temperature of the superfluid transition in the large-bipolaron liquid we identify regions in the phase diagram with the presence of PG (caused by the impact of the (bi)polarons potential on delocalized quasiparticles), CO and superconductivity. They are located in the same places in the diagram as in hole-doped cuprates, and, as in the latter, the shape of the calculated phase diagram is resistant to wide-range changes in the characteristics of the system. As in cuprates, the calculated temperature of the superconducting transition increases with the number of conducting planes in the unit cell, the superfluid density decreases with doping at overdoping, the bipolaron density (and bipolaronic plasmon energy) saturates at optimal doping. Thus, the similarity of the considered system with hole-doped cuprates is not limited to the phase diagram. The results obtained allow us to discuss ways of increasing the temperature of the superfluid transition in the large-bipolaron liquid and open up the possibility of studying the current-carrying state and properties of the bipolaron condensate.
Nanoporous silver fabricated with pretreated Ag–Al alloy toward surface enhanced Raman sensing
Authors: Jing Zhiyu , Dong Yongle , Zhang Ling 
Published: April 2024

Abstract
Nanoporous silver (NPS), characterized by its three-dimensional bi-continuous interpenetrating ligament channel structure, is a good candidate for surface enhanced Raman scattering (SERS), attributed to its exceptional surface-to-volume ratio and significant SERS enhancement capabilities. Here, we have successfully fabricated NPS through the dealloying of α-terpineol (α-TPN) coated Ag55Al45 alloy. The resulting α-NPS exhibits uniform ligaments and nanopore sizes, maintaining high SERS performance even after being exposed to air for more than one month. The pretreatment of precusor alloy with α-TPN is crucial not only for the formation of nanoporous structure but also for ensuring the long term stability of α-NPS. Specifically, α-TPN functions as a surfactant, facilitating atomic diffusion to achieve a superior interconnected NPS. Furthermore, during the dealloying process, the carbonization of α-TPN serves as a protective layer, effectively inhibiting the oxidation of silver.
Texture-preserving low dose CT image denoising using Pearson divergence
Authors: Oh Jieun , Wu Dufan , Hong Boohwi , Lee Dongheon , Kang Minwoong , Li Quanzheng , Kim Kyungsang 
Published: April 2024

Abstract

Objective. The mean squared error (MSE), also known as L
2 loss, has been widely used as a loss function to optimize image denoising models due to its strong performance as a mean estimator of the Gaussian noise model. Recently, various low-dose computed tomography (LDCT) image denoising methods using deep learning combined with the MSE loss have been developed; however, this approach has been observed to suffer from the regression-to-the-mean problem, leading to over-smoothed edges and degradation of texture in the image. Approach. To overcome this issue, we propose a stochastic function in the loss function to improve the texture of the denoised CT images, rather than relying on complicated networks or feature space losses. The proposed loss function includes the MSE loss to learn the mean distribution and the Pearson divergence loss to learn feature textures. Specifically, the Pearson divergence loss is computed in an image space to measure the distance between two intensity measures of denoised low-dose and normal-dose CT images. The evaluation of the proposed model employs a novel approach of multi-metric quantitative analysis utilizing relative texture feature distance. Results. Our experimental results show that the proposed Pearson divergence loss leads to a significant improvement in texture compared to the conventional MSE loss and generative adversarial network (GAN), both qualitatively and quantitatively. Significance. Achieving consistent texture preservation in LDCT is a challenge in conventional GAN-type methods due to adversarial aspects aimed at minimizing noise while preserving texture. By incorporating the Pearson regularizer in the loss function, we can easily achieve a balance between two conflicting properties. Consistent high-quality CT images can significantly help clinicians in diagnoses and supporting researchers in the development of AI-diagnostic models.
Effect of surface topography and roughness on the leakage of static seals
Authors: Gu Zhengpeng , Dai Qingwen , Huang Wei , Wang Xiaolei 
Published: April 2024

Abstract
Static seal is widely used in modern machinery. Leakage of static seals would shorten the mechanical system’s service life and affect the environment. To understand the leakage characteristics of static seals, in this work, an experimental apparatus for leakage quantization was built. The effects of surface topography and roughness on the leakage performance of static seals subject to elevated pressure were highlighted. It was found that the leakage rate is negatively correlated with contact pressure. Orientation of surface topography affects the leakage, where the grinding scar parallel to the leakage direction contributes to the leakage, and the perpendicular grinding scar has an inhibiting effect. The leakage rate of irregular and discontinuous surface topography is lower than that of regular ones, and it increases with increasing surface roughness. Furthermore, the leakage mechanism of surface topography and roughness was revealed. This work provides general guidance for the parameters design of static seals.