bluuebunny/crossref_metadata_2025_split huggingface dataset:
Defining Narratives of Identity in Canadian Political Science: Accounting for the Absence of Race
Authors: Nath Nisha 
Published: March 2011

Abstract.This article maps how Canadian political science has considered and shaped the logic of “identity” across the institutional, societal and governance dimensions of this disciplinary subfield. Focusing on the ubiquitous analytic absence of “race” in the mainstream literature, this article argues that mainstream Canadian political science reproduces a logic that limits the conversation to particular dimensions of ‘identity’ (‘identity’ as a basis of political action, a collective phenomenon denoting sameness and a core aspect of individual/collective selfhood) at the expense of others (‘identity’ as a product of social or political action, a product of multiple and competing discourses and a governmentality). In addition to this logic of ‘identity’, eight methodological tendencies in the mainstream literature further impede analyses of ‘race’. By challenging these methodological tendencies, abandoning ‘identity’ as ananalyticcategory and reflecting on the consequences of deactivating and erasing ‘race’, Canadian political scientists may become better equipped to interrogate the operating logic of ‘identity’, to substantively incorporate ‘race’ as a conceptual, analytic and explanatory device, and perhaps most critically, begin to redefine the canon.Résumé.Cet article retrace la manière dont la science politique canadienne a considéré et façonné la logique de «l'identité» dans certaines dimensions particulières de cette discipline, soit celles des institutions, de la société et de la gouvernance. En se concentrant sur l'absence prédominante du concept de «race» dans les analyses de la littérature conventionnelle, l'article soutient que la science politique canadienne dans la ligne du courant dominant reproduit une logique qui limite la conversation à certaines dimensions de «l'identité» (soit «l'identité» en tant que base de l'action politique, en tant que phénomène dénotant l'uniformité et en tant qu'aspect essentiel du moi individuel ou collectif) au détriment des autres (soit «l'identité» en tant que produit de l'action politique ou sociale, produit de discours multiples et rivaux, et gouvernementalité). Outre cette logique de «l'identité», huit tendances méthodologiques de la littérature conventionnelle entravent davantage les analyses de la «race». En contestant ces tendances méthodologiques, en abandonnant «l'identité» en tant que catégorieanalytiqueet en réfléchissant aux conséquences de la désactivation et de l'effacement de la «race», les politicologues canadiens pourraient devenir mieux équipés pour interroger la logique opérante de «l'identité», pour incorporer la «race» de manière substantielle en tant que dispositif conceptuel, analytique et explicatif, et peut-être le plus important, pour commencer à redéfinir le canon.
Replying to the anti-God challenge: a God without moral character acts well
Authors: FORREST PETER 
Published: March 2011

AbstractSeveral authors, including Stephen Law in this journal, have argued that the case for an evil God is (about) as strong as for a good God. In this article I take up the challenge on behalf of theists who, like Richard Swinburne, argue for an agent of unrestricted power and knowledge as the ultimate explanation of all contingent truths. I shall argue that an evil God is much less probable than a good one. I do so by (1) distinguishing the analogical predication of ‘good’ or ‘evil’ of God from the literal predication, (2) interpreting ‘acting in a morally good way’ to mean ‘acting like a good consequentialist’, and (3) relying on anaxiarchistthesis about agency that is congenial to theists and perhaps even presupposed by theism.
Linking farmers to community stores to increase consumption of local produce: a case study of the Navajo Nation
Authors: Setala Ashley , Gittelsohn Joel , Speakman Kristen , Oski Jane , Martin Tammy , Moore Regina , Tohannie Marcella , Bleich Sara N 
Published: March 2011

AbstractObjectiveTo understand the barriers to farmer participation in Farm-to-Table (F2T) programmes and to identify possible solutions to these obstacles.DesignCross-sectional analysis of farmer perspectives on F2T programmes.SettingThree service units on the Navajo Nation (Chinle, Tuba City and Fort Defiance).SubjectsForty-four Navajo farmers.ResultsMost participants reported that farming on the Navajo Nation is getting harder (61 %) but that it is very important to maintain Navajo farming traditions (98 %). A modest number of farmers (43 %) expressed interest in participating in an F2T programme. All farmers reported that childhood obesity was a very serious or serious problem in the Navajo Nation. The farmers expressed support for an F2T programme if key barriers to farming, including water access and pest control, could be addressed. Key barriers to participation identified included lack of fruits and vegetables to sell, sale price of crops and lack of certification of produce by the US Food and Drug Administration.ConclusionsNavajo farmers are aware of the burden of childhood obesity on the Navajo Nation and feel that an F2T programme could be beneficial. To successfully implement a Farm-to-Table programme, the barriers to participation identified will need to be addressed.
Incomplete Harmonization Contracts in International Economic Law: Report of the Panel, China – Measures Affecting the Protection and Enforcement of Intellectual Property Rights, WT/DS362/R, adopted 20 March 2009
Authors: SAGGI KAMAL , TRACHTMAN JOEL P. 
Published: March 2011

AbstractIn China – Measures Affecting the Protection and Enforcement of Intellectual Property Rights, the Panel addressed three main issues:
1.the relationship between China's censorship laws and its obligations to protect copyright under the WTO Agreement on Trade Related Intellectual Property Rights (‘TRIPS’);2.China's obligations under TRIPS to ensure that its customs authorities be empowered to dispose properly of confiscated goods that infringe intellectual property rights;3.whether China's volume and value of goods thresholds for application of criminal procedures and penalties with respect to trademark counterfeiting or copyright piracy comply with TRIPS requirements for application of criminal procedures and penalties.
US Compliance with WTO Rulings on Zeroing in Anti-Dumping
Authors: HOEKMAN BERNARD , WAUTERS JASPER 
Published: March 2011

AbstractThis paper reviews the WTO Appellate Body Reports on United States–Zeroing (EC) (Article 21.5 DSU – EC) (WT/DS294/AB/RW, 14 May 2009) and United States–Zeroing (Japan) (Article 21.5 DSU – Japan) (WT/DS322/AB/RW, 18 August 2009). The Appellate Body found that the United States had not brought its anti-dumping measures into compliance with the WTO Anti-Dumping Agreement as it continued to use zeroing in annual reviews of anti-dumping orders. We argue that this conclusion – based on a complicated discussion of what constitutes a ‘measure taken to comply’ – could have been reached through a much simpler and direct argument. Continued noncompliance by the United States generates costs to traders targeting the United States and the trading system more generally. We argue that from a broader WTO compliance perspective consideration should be given to stronger multilateral surveillance of anti-dumping practice by all WTO members and to more analysis and effective communication by economists regarding the costs of zeroing and anti-dumping practices more generally.
‘Optimal’ Retaliation in the WTO – a commentary on the Upland Cotton Arbitration
Authors: GROSSMAN GENE M. , SYKES ALAN O. 
Published: March 2011

AbstractThe Upland Cotton case raises a range of interesting issues regarding the rationale for retaliation in the WTO system and the proper approach to its calibration. These include: Should the approach to retaliation differ in cases involving prohibited or actionable subsidies? When should cross-retaliation be allowed? Should retaliation be based only on the harm to the complaining nation, or to other nations as well? And, most importantly, what economic content can be given to the standard of countermeasures ‘equivalent to the level of nullification or impairment’? We address these and other issues from both a legal and economic perspective, with particular attention to the question of what level of retaliation will restore the lost welfare of the complaining nation.
Genomic and proteomic analyses of the coral pathogen Vibrio coralliilyticus reveal a diverse virulence repertoire
Authors: de O Santos Eidy , Alves Nelson , Dias Graciela M , Mazotto Ana Maria , Vermelho Alane , Vora Gary J , Wilson Bryan , Beltran Victor H , Bourne David G , Le Roux Frédérique , Thompson Fabiano L 
Published: March 2011

Abstract
Vibrio coralliilyticus has been implicated as an important pathogen of coral species worldwide. In this study, the nearly complete genome of Vibrio coralliilyticus strain P1 (LMG23696) was sequenced and proteases implicated in virulence of the strain were specifically investigated. The genome sequence of P1 (5 513 256 bp in size) consisted of 5222 coding sequences and 58 RNA genes (53 tRNAs and at least 5 rRNAs). Seventeen metalloprotease and effector (vgrG, hlyA and hcp) genes were identified in the genome and expressed proteases were also detected in the secretome of P1. As the VcpA zinc-metalloprotease has been considered an important virulence factor of V. coralliilyticus, a vcpA deletion mutant was constructed to evaluate the effect of this gene in animal pathogenesis. Both wild-type and mutant (ΔvcpA) strains exhibited similar virulence characteristics that resulted in high mortality in Artemia and Drosophila pathogenicity bioassays and strong photosystem II inactivation of the coral dinoflagellate endosymbiont (Symbiodinium). In contrast, the ΔvcpA mutant demonstrated higher hemolytic activity and secreted 18 proteins not secreted by the wild type. These proteins included four types of metalloproteases, a chitinase, a hemolysin-related protein RbmC, the Hcp protein and 12 hypothetical proteins. Overall, the results of this study indicate that V. coralliilyticus strain P1 has a diverse virulence repertoire that possibly enables this bacterium to be an efficient animal pathogen.
Nitrogen fixation and transfer in open ocean diatom–cyanobacterial symbioses
Authors: Foster Rachel A , Kuypers Marcel M M , Vagner Tomas , Paerl Ryan W , Musat Niculina , Zehr Jonathan P 
Published: March 2011

Abstract
Many diatoms that inhabit low-nutrient waters of the open ocean live in close association with cyanobacteria. Some of these associations are believed to be mutualistic, where N2-fixing cyanobacterial symbionts provide N for the diatoms. Rates of N2 fixation by symbiotic cyanobacteria and the N transfer to their diatom partners were measured using a high-resolution nanometer scale secondary ion mass spectrometry approach in natural populations. Cell-specific rates of N2 fixation (1.15–71.5 fmol N per cell h−1) were similar amongst the symbioses and rapid transfer (within 30 min) of fixed N was also measured. Similar growth rates for the diatoms and their symbionts were determined and the symbiotic growth rates were higher than those estimated for free-living cells. The N2 fixation rates estimated for Richelia and Calothrix symbionts were 171–420 times higher when the cells were symbiotic compared with the rates estimated for the cells living freely. When combined, the latter two results suggest that the diatom partners influence the growth and metabolism of their cyanobacterial symbionts. We estimated that Richelia fix 81–744% more N than needed for their own growth and up to 97.3% of the fixed N is transferred to the diatom partners. This study provides new information on the mechanisms controlling N input into the open ocean by symbiotic microorganisms, which are widespread and important for oceanic primary production. Further, this is the first demonstration of N transfer from an N2 fixer to a unicellular partner. These symbioses are important models for molecular regulation and nutrient exchange in symbiotic systems.
Effect of warming and drought on grassland microbial communities
Authors: Sheik Cody S , Beasley William Howard , Elshahed Mostafa S , Zhou Xuhui , Luo Yiqi , Krumholz Lee R 
Published: March 2011

Abstract
The soil microbiome is responsible for mediating key ecological processes; however, little is known about its sensitivity to climate change. Observed increases in global temperatures and alteration to rainfall patterns, due to anthropogenic release of greenhouse gases, will likely have a strong influence on soil microbial communities and ultimately the ecosystem services they provide. Therefore, it is vital to understand how soil microbial communities will respond to future climate change scenarios. To this end, we surveyed the abundance, diversity and structure of microbial communities over a 2-year period from a long-term in situ warming experiment that experienced a moderate natural drought. We found the warming treatment and soil water budgets strongly influence bacterial population size and diversity. In normal precipitation years, the warming treatment significantly increased microbial population size 40–150% but decreased diversity and significantly changed the composition of the community when compared with the unwarmed controls. However during drought conditions, the warming treatment significantly reduced soil moisture thereby creating unfavorable growth conditions that led to a 50–80% reduction in the microbial population size when compared with the control. Warmed plots also saw an increase in species richness, diversity and evenness; however, community composition was unaffected suggesting that few phylotypes may be active under these stressful conditions. Our results indicate that under warmed conditions, ecosystem water budget regulates the abundance and diversity of microbial populations and that rainfall timing is critical at the onset of drought for sustaining microbial populations.
Game Changer
Authors: McLeod Lateef 
Published: March 2011

Abstract
Individuals with significant communication challenges need to communicate across many different venues. The author, from the perspective of an individual who uses AAC, discusses the strengths and weaknesses of both traditional AAC technologies and new mobile AAC technologies. He describes how access to AAC has allowed him to fulfill his dreams as a presenter and writer. He successfully manages a blog in San Francisco, writes grants, and has published his first book of poetry. Not one AAC device fits all of his communication needs; however, access to mobile technology tools has increased his flexibility across environments and given him another successful tool for communication.
The iPad: A Cool Communicator on the Go
Authors: Hyatt Glenda Watson 
Published: March 2011

Abstract
Glenda Watson Hyatt, Web accessibility consultant, blogger, and user of AAC, shares her perspective on new mobile AAC technologies. A history of Glenda's use of AAC is chronicled from her early low-tech strategies to her recent embracing of new mobile AAC technologies. She recounts purchasing an iPad and her early experiences attempting to use it as an AAC system in a variety of contexts. Strengths, weaknesses, and projections for the future are highlighted in this personal sharing of a user perspective.
The caBIG® Life Science Business Architecture Model
Authors: Boyd Lauren Becnel , Hunicke-Smith Scott P. , Stafford Grace A. , Freund Elaine T. , Ehlman Michele , Chandran Uma , Dennis Robert , Fernandez Anna T. , Goldstein Stephen , Steffen David , Tycko Benjamin , Klemm Juli D. 
Published: March 2011

Abstract
Motivation: Business Architecture Models (BAMs) describe what a business does, who performs the activities, where and when activities are performed, how activities are accomplished and which data are present. The purpose of a BAM is to provide a common resource for understanding business functions and requirements and to guide software development. The cancer Biomedical Informatics Grid (caBIG®) Life Science BAM (LS BAM) provides a shared understanding of the vocabulary, goals and processes that are common in the business of LS research.
Results: LS BAM 1.1 includes 90 goals and 61 people and groups within Use Case and Activity Unified Modeling Language (UML) Diagrams. Here we report on the model's current release, LS BAM 1.1, its utility and usage, and plans for future use and continuing development for future releases.
Availability and Implementation: The LS BAM is freely available as UML, PDF and HTML (https://wiki.nci.nih.gov/x/OFNyAQ).
Contact: lbboyd@bcm.edu; laurenbboyd@gmail.com
Supplementary information: Supplementary data) are avaliable at Bioinformatics online.
pathClass: an R-package for integration of pathway knowledge into support vector machines for biomarker discovery
Authors: Johannes Marc , Fröhlich Holger , Sültmann Holger , Beißbarth Tim 
Published: March 2011

Abstract
Summary: Prognostic and diagnostic biomarker discovery is one of the key issues for a successful stratification of patients according to clinical risk factors. For this purpose, statistical classification methods, such as support vector machines (SVM), are frequently used tools. Different groups have recently shown that the usage of prior biological knowledge significantly improves the classification results in terms of accuracy as well as reproducibility and interpretability of gene lists. Here, we introduce pathClass, a collection of different SVM-based classification methods for improved gene selection and classfication performance. The methods contained in pathClass do not merely rely on gene expression data but also exploit the information that is carried in gene network data.
Availability: pathClass is open source and freely available as an R-Package on the CRAN repository at http://cran.r-project.org
Contact: m.johannes@dkfz-heidelberg.de; tim.beissbarth@ams.med.uni-goettingen.de
A qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk
Authors: Sankar Martial , Osmont Karen S. , Rolcik Jakub , Gujas Bojan , Tarkowska Danuse , Strnad Miroslav , Xenarios Ioannis , Hardtke Christian S. 
Published: March 2011

Abstract
Motivation: Hormone pathway interactions are crucial in shaping plant development, such as synergism between the auxin and brassinosteroid pathways in cell elongation. Both hormone pathways have been characterized in detail, revealing several feedback loops. The complexity of this network, combined with a shortage of kinetic data, renders its quantitative analysis virtually impossible at present.
Results: As a first step towards overcoming these obstacles, we analyzed the network using a Boolean logic approach to build models of auxin and brassinosteroid signaling, and their interaction. To compare these discrete dynamic models across conditions, we transformed them into qualitative continuous systems, which predict network component states more accurately and can accommodate kinetic data as they become available. To this end, we developed an extension for the SQUAD software, allowing semi-quantitative analysis of network states. Contrasting the developmental output depending on cell type-specific modulators enabled us to identify a most parsimonious model, which explains initially paradoxical mutant phenotypes and revealed a novel physiological feature.
Availability: The package SQUADD is freely available via the Bioconductor repository at http://www.bioconductor.org/help/bioc-views/release/bioc/html/SQUADD.html.
Contact: martial.sankar@unil.ch; christian.hardtke@unil.ch
Supplementary information: Supplementary data are available at Bioinformatics online.
High-dimensional pharmacogenetic prediction of a continuous trait using machine learning techniques with application to warfarin dose prediction in African Americans
Authors: Cosgun Erdal , Limdi Nita A. , Duarte Christine W. 
Published: March 2011

Abstract
Motivation: With complex traits and diseases having potential genetic contributions of thousands of genetic factors, and with current genotyping arrays consisting of millions of single nucleotide polymorphisms (SNPs), powerful high-dimensional statistical techniques are needed to comprehensively model the genetic variance. Machine learning techniques have many advantages including lack of parametric assumptions, and high power and flexibility.
Results: We have applied three machine learning approaches: Random Forest Regression (RFR), Boosted Regression Tree (BRT) and Support Vector Regression (SVR) to the prediction of warfarin maintenance dose in a cohort of African Americans. We have developed a multi-step approach that selects SNPs, builds prediction models with different subsets of selected SNPs along with known associated genetic and environmental variables and tests the discovered models in a cross-validation framework. Preliminary results indicate that our modeling approach gives much higher accuracy than previous models for warfarin dose prediction. A model size of 200 SNPs (in addition to the known genetic and environmental variables) gives the best accuracy. The R2 between the predicted and actual square root of warfarin dose in this model was on average 66.4% for RFR, 57.8% for SVR and 56.9% for BRT. Thus RFR had the best accuracy, but all three techniques achieved better performance than the current published R2 of 43% in a sample of mixed ethnicity, and 27% in an African American sample. In summary, machine learning approaches for high-dimensional pharmacogenetic prediction, and for prediction of clinical continuous traits of interest, hold great promise and warrant further research.
Contact: cduarte@uab.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
MRSD: a web server for Metabolic Route Search and Design
Authors: Xia Deguo , Zheng Haoran , Liu Zhiqiang , Li Guisheng , Li Jinlong , Hong Jiong , Zhao Kai 
Published: March 2011

Abstract
Summary: We present a tool called MRSD (Metabolic Route Search and Design) to search and design routes based on the weighted compound transform diagraph. The search submodule returns routes between a source and product compound within seconds in the network of one or multiple organisms based on data from KEGG. The design submodule designs a route from an appointed compound in an interactive mode. The two complementary functions, Metabolic Route Search and Design, can be broadly used in biosynthesis, bio-pharmaceuticals and the other related fields.
Availability: bioinfo.ustc.edu.cn/softwares/MRSD/
Contact: hrzheng@ustc.edu.cn
Supplementary information: Supplementary data are available at the Bioinformatics online.