bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating a Calcium Alginate-Xylitol Coating Methodology for Controlled Release Profiles of Multivitamin Tablet as a Model Drug
Authors: Kim Raehyun 
Published: May 2024

The drug delivery system promotes the release of the active pharmaceutical ingredient (API) to attain the desired therapeutic effect at the time most needed. Alginate is a natural polymer that is frequently employed in drug delivery systems. Calcium alginate can simply coat as a film type on the surface of a tablet, which might be created to be dissolved more quickly and predictably manners in the gastric fluid to deliver as needed in a patient-friendly system. In this study, the sodium alginate solution was reacted with a predetermined calcium compound and xylitol combination, while the multivitamin tablets’ surface was coated with calcium suppliers such as calcium chloride. Then, the coated tablets were subjected to a dissolution test in a simulated gastric fluid. Our study results showed that the sphere formation was excellent in terms of strength and size in 1.0% sodium alginate with 4% calcium chloride. Average sphere sizes were 0.5 ~ 2.0 mm. Their break force was 3.5 N, And the dissolution was the fastest in the coated tablets with 1% sodium alginate and calcium chloride. The dissolution rate was changed proportionally with calcium concentration. A high feasibility of dissolution rate was positively found. When a high concentration of xylitol was mixed with 4% calcium chloride, the dissolution rate was proportional to the concentration of xylitol. In conclusion, the study demonstrated that the dissolution rate of tablets with API might be controllable with the calcium alginate film coating with xylitol.
State-of-the-Art Energy-Consumption Optimization Solutions for Mobile Ad-Hoc Networks
Authors: Admin Admin 
Published: May 2024

The Peta Journal of Social Science and Humanity (PJSSH) is an open access, peer-reviewed international journal that deals with both applied and theoretical issues. Special Issues devoted to important topics in social science will occasionally be published. The main objective of JSS is to offer an intellectual platform to the international scholars and it aims to promote interdisciplinary studies in social science. Generally, accepted papers will appear online within 3 weeks followed by printed hard copy.
Teachers’ Perspective on Using Oral Peer Feedback in Public Speaking
Authors: Novita Sari Hidayat  , Oikurema Purwanti  , Slamet Setiawan  
Published: May 2024

Assessment activities are closely related to the process of learning activities that cannot be separated. There are three processes in teaching and learning activities. That is input, process and output. Peer assessment has an important role in an English learning process, especially in the realm of speaking. Input is the student himself, the process is related to the curriculum, teaching materials, and teaching methods. And output is the result of learning. Assessment is available in all three domains. Assessment is carried out before the learning process, when learning is carried out, and after learning is carried out. Because of the importance of assessment factors in learning, there are many forms of assessment during learning. One form of assessment that supports the process of learning English in the realm of speaking is peer assessment activities. Some researchers believe that peer assessment plays an active and beneficial role for both students and teachers themselves. This qualitative research aims to determine and evaluate the benefits of peer assessment and perceptions of four subject teachers in an upper secondary school as teaching material from the results of assessments conducted by their students. Data was obtained through semi-structured interviews containing opinions, challenges and benefits from the application they obtained from this oral peer feedback assessment method
Hubungan Kemampuan Manajerial Kepala Sekolah, Iklim Kerja Sekolah, Motivasi Kerja, dan Kepuasan Kerja dengan Komitmen Organisasional Guru SMP Swasta di Kota Denpasar
Authors: Ariyasa I Putu , Yudana I Made , Dantes Kadek Rihendra 
Published: May 2024

Penelitian ini bertujuan untuk mengetahui: hubungan kemampuan manajerial kepala sekolah, iklim kerja sekolah, motivasi kerja, dan kepuasan kerja dengan komitmen organisasional Guru SMP swasta di Kota Denpasar. Penentuan sampel pada penelitian ini menggunakan teknik area random sampling, yang mengambil sampel guru yang bekerja di SMP swasta Kota Denpasar sebanyak 276 orang. Penelitian ini dirancang dalam bentuk penelitian ex-post facto. Data dalam penelitian ini dikumpulkan dengan menggunakan kuesioner komponen konteks kemampuan manajerial kepala sekolah, iklim kerja sekolah, motivasi kerja, dan kepuasan kerja dengan komitmen organisasional. Data dianalisis dengan regresi sederhana, korelasi sederhana, korelasi ganda, regresi ganda, korelasi parsial, dan analisis determinasi.Hasil penelitian menunjukkan bahwa: (1) terdapat hubungan yang positif dan signifikan antara kemampuan manajerial kepala sekolah dengan komitmen organisasional guru dengan koefisien korelasi sebesar 0,161 dan sumbangan efektif sebesar 5,47%, (2) terdapat hubungan yang positif dan signifikan antara iklim kerja sekolah dengan komitmen organisasional guru dengan koefisien korelasi sebesar 0,467 dan sumbangan efektif sebesar 6,78%, (3) terdapat hubungan yang positif dan signifikan motivasi kerja dengan komitmen organisasional guru dengan koefisien korelasi sebesar 0,479 dan sumbangan efektif sebesar1,05%, (4) terdapat hubungan yang positif dan signifikan kepuasan kerja guru dengan komitmen organisasional guru dengan koefisien korelasi sebesar 0,480 dan sumbangan efektif sebesar 12,20%, dan (5) terdapat hubungan yang positif dan signifikan secara simultan kemampuan manajerial kepala sekolah, iklim kerja sekolah, motivasi kerja, dan kepuasan kerja guru terhadap komitmen organisasional guru dengan koefisien korelasi ganda sebesar 0,505 dan sumbangan efektif sebesar 25,50%.
Pengaruh Pendekatan Steam-Loose Parts terhadap Kemampuan Literasi Numerasi Anak Usia Dini
Authors: Nufus Asyifa’un , Arianto Fajar , Dewi Utari 
Published: May 2024

The study aimed to identify the approach STEAM-Loose Parts of the ability of literasi numeracy in children aged 3-4 years in Pre School of SKB Sidoarjo. During the observation, several pre school of SKB Sidoarjo were found to have low numeracy skills among the children. The low numeracy skills in children aged 3-4 years are caused by the general nature of mathematics education, which is rarely linked to activities or daily life. However, numeracy skills can help children solve everyday life problems. This study uses the one group design pretest-postest method and uses non parametric data analysis techniques with the help of the wilcoxon match pairs test formula because the subjects only 6 childrens. The result of this research shows that getting the pre-test average is 43,3 and the post-test of 85,0 data shows that the STEAM-Loose Parts learning has a significant impact on the numeration capabilities of 3-4 years old in the pre school of SKB Sidoarjo.
Motivasi, Humanisme, dan Transendensi dalam Sekumpulan Puisi Felix Mencuci Piring Karya Tengsoe Tjahjono
Authors: Kusmiyati Yatik , Supratno Haris , Indarti Titik 
Published: May 2024

This research aims to describe the poems contained in the collection of poems Felix Mencuci Piring by Tengsoe Tjahjono. Literary reception is a literary genre that examines literary texts by considering the reader as the person giving the welcome or response. Readers in giving remarks and responses are influenced by factors of space, time and social group. The data collection technique in this research uses library or document techniques. The results of this research show that in a collection of poems, Felix Mencuci Piring is a poem that is full of motivation, humanization and transcendence. The poems in the book awaken the reader's self-awareness to always be careful, caring, and aware of God presence in every aspect of life.
La influencia de la inteligencia artificial en la personalización del aprendizaje: Perspectivas y desafíos en la educación
Authors: Mera Castillo Debora Elizabeth 
Published: May 2024

La presente investigación explora la influencia de la inteligencia artificial (IA) en la personalización del aprendizaje en el ámbito educativo, con el objetivo de identificar perspectivas y desafíos. Para ello, se empleó una metodología cualitativa que consistió en un análisis exhaustivo de la literatura académica y científica relacionada con el tema. Los resultados revelan que la IA ofrece herramientas digitales innovadoras que permiten adaptar el contenido educativo a las necesidades individuales de los estudiantes, promoviendo así un aprendizaje más efectivo y significativo. Sin embargo, se identificaron desafíos importantes, como la accesibilidad equitativa a la tecnología, la resistencia al cambio por parte de algunos educadores y las preocupaciones éticas y de privacidad relacionadas con la recopilación y el uso de datos. Estos hallazgos resaltan la importancia de abordar estos desafíos de manera proactiva y colaborativa entre investigadores, educadores y desarrolladores de tecnología para maximizar los beneficios de la IA en la personalización del aprendizaje.
Rozwój społeczno-gospodarczy ośrodków miejskich na Mazowszu Północnym w okresie II Rzeczypospolitej na przykładzie Ostrołęki i Makowa Mazowieckiego (analiza porównawcza)
Authors: Budelewski Dariusz 
Published: May 2024

Ostrołęka podczas I wojny światowej została dotkliwie zniszczona. Początkowo sytuacja gospodarcza Ostrołęki poprawiała się powoli, ale z czasem miasto stopniowo się rozwijało. Wyraźnie wzrosło budownictwo oraz ilość zakładów przemysłowych i rzemieślniczych. Zwiększyła się też liczba ludności. Dobrze rozwijało się szkolnictwo i życie kulturalne. Maków Mazowiecki początkowo borykał się z podobnymi problemami społeczno–gospodarczymi jak Ostrołęka. Miasto jednak pokonywało trudności i stopniowo postępował jego rozwój. Dobrze rozwijało się rzemiosło i handel oraz spółdzielczość. Poprawiała się także sytuacja w szkolnictwie i nastąpiło ożywienie życia kulturalnego. Niestety, w porównaniu z Ostrołęką liczba ludności miasta wzrastała dużo wolniej.
Principal Component Analysis of Cognitive Executive Functions: A Predictive Model of Academic Performance of Students in Mathematics in Secondary Schools
Authors: Akpan Ekemini T. , Umoh Joseph B. , James Godwin D. 
Published: May 2024

There is a growing interest from instructional scientists in using parameters of brain executive functions to unfold cognitive disorders, Mathematical Learning Difficulties (MLD), and assessment of learners’ academic performance. Thus, it is imperative to investigates, extracts and classify the major principal components of learners’ cognitive executive functions that predict academic performance of students in Mathematics and science related courses in secondary schools. An ex post facto quasi-experimental design was adopted for the study. Students’ cognitive profile was measured using a validated and reliable cognitive assessment Battery (CAB) application. There were significant positive correlations between cognitive executive functions and academic performance of students in Mathematics. The major components of the executive functions that accounted for substantial effects on academic performance of students in Mathematics include working memory, conceptual memory, short-term memory, inhibition, updating, focus attention, divided attention, auditory perception, and visual perception. Also, processing speed, shifting, planning, hand-eye coordination and response time accounted for moderate effects on academic performance of students in Mathematics. Consequently, instructors should reinforce learners’ cognitive processes using cognitive retraining programmes, personalized learning, differentiated instructional strategies for exceptional students, and offer therapeutic interventions on the identified cognitive parameters that could reduce extraneous cognitive loads. These could facilitate mental internalization of external perception during instructional delivery and learning.
Preparation and Characterization of Ferrihydrite: Application in Arsenic Removal from Aqueous Solutions
Authors: Tiendrebéogo Rasmane , Sanou Yacouba , Paré Samuel , Senou Aboubacar 
Published: May 2024

Arsenic pollution is a public health hazard in Burkina Faso due to its impact on human health and water resources. To mitigate this pollution, ferrihydrite material has been synthesized and characterized to be used as adsorbent for arsenic removal in aqueous solutions. This study aimed to contribute to improve of access to clean drinking water by removing arsenic from water using ferrihydrite. Arsenic species such as As(III) and As(V) were removed through batch adsorption. Experiments were carried out in batch mode using arsenic aqueous solutions. The characterization of ferrihydrite using Scanning Electron Microscopy (SEM) coupled with Energy Dispersive Spectroscopy (EDX), X-ray Diffraction (XRD), Infrared (IR), and Brunauer Emmett Teller (BET) showed that an amorphous and microporous 2-line ferrihydrite. The total specific surface area and pH at point of zero charge (pHpzc) were 184.518 m²/g and 9.41, respectively. The optimal adsorbent doses were 4 g/L for As (V) and 8 g/L for As (III). The optimum pH range for the adsorption of As (V) and As (III) was between 2 and 10, The maximum adsorption capacity was 15.07 mg/g for As(V) and 13.01 mg/g for As(III) with increasing concentration between 2 and 16 mg/L. Equilibrium time for As (V) and As (III) on ferrihydrite was found to be 720 min and 960 min, respectively. The adsorption of As(V) and As(III) was consistent with the Langmuir monolayer model on ferrihydrite. Arsenic adsorption was occurred according to spontaneous chemical reaction. Arsenic removal was occurred on a monolayer following the pseudo-second order kinetic.
Sero-prevalence of Human Immunodeficiency Virus among Students Undergoing Medical Examination in a Tertiary Institution
Authors: Huldah Hanson Asikiya , Renner Briggs Bieye 
Published: May 2024

Aims: To assess the prevalence of human immunodeficiency virus among students undergoing medical checkup in a tertiary institution.
Study Design: The investigation utilised a cross-sectional study design technique.
Methodology: In this present study, 2114 participants were included in the age range 15-49 years. Serological method was used to detect the presence of HIV using a rapid diagnostic technique using determine. Tile method was used to determine the ABO and Rhesus D antigens in the individuals.
Results: Out of the 2114 participants sampled, the population studied according to various departments within the university were ME 95 (5%), EM 181 (9%), LIB 101 (5%), SPE 63 (3%), ENG 296 (14%), BIO 423 (20%), CHE 150 (7%), COM 305 (14%), MGT 236 (11%) and ACC 236 (12%). The prevalence of HIV among tertiary institution students is 1%.
Conclusion: This research gives an insight into the prevalence of HIV among students in tertiary institution for strategic intervention.
Effect of Time Interval, IBA and Rooting Media on Air Layering in Guava (Psidium guajava L.) cv. L-49
Authors: Meena Pooja Kakarwal , Joseph Annjoe V. , Bahadur Vijay , Shubham . 
Published: May 2024

The experiment was conducted at Department of Horticulture, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj during the year 2023–2024. The experiment was laid out in randomized block design with three replications, and the study consists of Twelve treatment combinations by using two different concentrations of IBA viz., 4000 and 5000 ppm and four time of layering viz., 15th July, 30th July, 15th August, 30th August. The result indicated that treatment T9, i.e. Air layering done on 15th July using IBA 5000 ppm was found to be the most effective for better rooting and growth parameters, and gave the best results with respect to number of days of root formation (32days), number of roots per layering (12.75), root length (7.82cm), root thickness (9.61mm), 83.33% success in rooting, number of new leaves (25.23), number of new sprouts (11.83), length of new shoot (6.67 cm) and survival percentage after transplant into polybags (94.44%), that was significantly higher as compared to other treatment combination. On the basis of result obtained in the present investigation, it can be concluded that air-layering performed during 15th July, treated with 5000 ppm IBA concentration with cocopeat and sphagnum moss have been found better compared to all other treatment under subtropical condition of prayagraj, Uttar Pradesh.
Distal extremity pain as a presenting feature of Fabry's disease
Authors: Pagnini Ilaria , Borsini Walter , Cecchi Franco , Sgalambro Aurelio , Olivotto Iacopo , Frullini Anna , Cimaz Rolando 
Published: October 2010

AbstractObjectiveFabry's disease (FD) is an X‐linked lysosomal storage disease. Distal extremity pain can be an early finding and renal, cardiac, and cerebrovascular complications may lead to complications and mortality. Treatment is now available for these patients, who may not be diagnosed correctly for years if the neuropathic nature of the pain is not recognized. The aim of our study was to describe early clinical features in a cohort of patients with FD and to emphasize the importance of distal extremity pain for early diagnosis.MethodsThe medical charts of 35 patients with FD followed in a single center were reviewed. When data were incomplete, a detailed pain questionnaire was sent to patients. Nonresponders were contacted by telephone.ResultsDistal extremity pain was present in the majority of cases (25 of 35). The mean age at diagnosis of FD was 43.5 years (range 5–77 years). Distal extremity pain was more prevalent in males than females and occurred mostly in childhood or adolescence. When present at onset, the disease progressed with subsequent organ system involvement. Misdiagnoses were frequent and included growing pains, juvenile idiopathic arthritis, connective tissue disease, and gout.ConclusionClinical manifestations of FD, including episodes of severe pain in the feet and hands, often start in childhood. Distal extremity pain may be the only symptom for a considerable period of time. Patients may be wrongly labeled as having rheumatologic conditions, resulting in long diagnostic and therapeutic delays. Rheumatologists should be aware of the clinical aspects of FD and include it in the differential diagnosis of distal extremity pain in childhood and adolescence.
Classical Hodgkin's lymphoma arising in different host's conditions: Pathobiology parameters, therapeutic options, and outcome
Authors: Carbone Antonino , Spina Michele , Gloghini Annunziata , Tirelli Umberto 
Published: October 2010

AbstractEpidemiologic and molecular findings suggest that classical Hodgkin's lymphoma (CHL) is not a single disease but consists of more than one entity and may occur in different clinical settings. This review analyzes similarities and disparities among CHL entities arising in different host's conditions with respect to pathobiology parameters, therapeutic options, and outcome. For the purpose of this analysis, CHL entities have been subdivided according to the immune status of the host. In nonimmunosuppressed hosts, according to the age, CHL include pediatric, adult, and elderly forms, whereas, in immunosuppressed hosts, according to the type of immunosuppression, CHL include human immunodeficiency virus (HIV)‐associated, iatrogenic, and post‐transplant types. CHL entities in different settings are similar in morphology of neoplastic cells, expression of activation markers, and aberrations/activation of NFKB, JAK/STAT, and P13K/AKT pathways, but differ in the association with Epstein‐Barr virus (EBV) infection, persistent B‐cell phenotype, and cellular background composition. Large B‐cell lymphomas resembling CHL may also be observed in the same clinical settings. These lesions, however, do not fulfill the diagnostic criteria of CHL and clinically display a very aggressive behavior. In this article, current treatment options for the CHL entities, especially for elderly CHL and HIV‐associated CHL, are specifically reviewed. ABVD remains the gold standard both in nonimmunosuppressed or immunosuppressed hosts even if there are several data suggesting a possible improvement in outcome using the aggressive BEACOPP regimen in advanced stages. Refractory CHL, a clinical condition that may occur throughout the entire spectrum of CHL, is discussed separately. Am. J. Hematol., 2011. © 2010 Wiley‐Liss, Inc.
Autophagy induction by Bcr‐Abl‐expressing cells facilitates their recovery from a targeted or nontargeted treatment
Authors: Crowley Lisa C. , Elzinga Baukje M. , O'Sullivan Gerald C. , McKenna Sharon L. 
Published: October 2010

AbstractAlthough Imatinib has transformed the treatment of chronic myeloid leukemia (CML), it is not curative due to the persistence of resistant cells that can regenerate the disease. We have examined how Bcr‐Abl‐expressing cells respond to two mechanistically different therapeutic agents, etoposide and Imatinib. We also examined Bcr‐Abl expression at low and high levels as elevated expression has been associated with treatment failure. Cells expressing low levels of Bcr‐Abl undergo apoptosis in response to the DNA‐targeting agent (etoposide), whereas high‐Bcr‐Abl‐expressing cells primarily induce autophagy. Autophagic populations engage a delayed nonapoptotic death; however, sufficient cells evade this and repopulate following the withdrawal of the drug. Non‐Bcr‐Abl‐expressing 32D or Ba/F3 cells induce both apoptosis and autophagy in response to etoposide and can recover. Imatinib treatment induces both apoptosis and autophagy in all Bcr‐Abl‐expressing cells and populations rapidly recover. Inhibition of autophagy with ATG7 and Beclin1 siRNA significantly reduced the recovery of Imatinib‐treated K562 cells, indicating the importance of autophagy for the recovery of treated cells. Combination regimes incorporating agents that disrupt Imatinib‐induced autophagy would remain primarily targeted and may improve response to the treatment in CML. Am. J. Hematol., 2011. © 2010 Wiley‐Liss, Inc.
The behavioral phenotype of the Angelman syndrome
Authors: Williams Charles A. 
Published: October 2010

AbstractThe Angelman syndrome is clinically delineated by the combination of seizures, absent speech, hypermotoric and ataxic movements and certain remarkable behaviors. Those with the syndrome have a predisposition toward apparent happiness and paroxysms of laughter, and this finding helps distinguish Angelman syndrome from other ones involving severe developmental handicap. In this review the core neurological features of the syndrome are discussed with a focus on those behaviors that make Angelman syndrome a prototypical genetic disorder expressing a behavioral phenotype. © 2010 Wiley‐Liss, Inc.
Neurobehavioral phenotype in Prader–Willi syndrome
Authors: Whittington Joyce , Holland Anthony 
Published: October 2010

AbstractThe focus of this article is on the lifetime development of people with Prader–Willi syndrome (PWS) and specifically on the neurobehavioral phenotype. We consider studies of this aspect of the phenotype (the “behavioral phenotype” of the syndrome) that have confirmed that there are specific behaviors and psychiatric disorders, the propensities to which are increased in those with PWS, and cannot be accounted for by other variables such as IQ or adaptive behavior. Beginning with a description of what is observed in people with PWS, we review the evolving PWS phenotype and consider how some aspects of the phenotype might be best explained, and how this complex phenotype may relate to the equally complex genotype. We then consider in more detail some of the neurobehavioral aspects of the phenotype listed above that raise the greatest management problems for parents and carers. © 2010 Wiley‐Liss, Inc.