bluuebunny/crossref_metadata_2025_split huggingface dataset:
أثر برنامج إرشادي معرفي سلوكي في خفض حدة الشعور بالوحدة النفسية لدى طالبات جامعة السيد محمد بن علي السنوسي الإسلامية بمدينة البيضاء
Authors: حسين د. فاطمة 
Published: June 2024

استهدفت الدراسة معرفة أثر برنامج معرفي سلوكي لخفض حدة الشعور بالوحدة النفسية لدى طالبات كلية أصول الدين بجامعة السيد محمد بن علي السنوسي الإسلامية بمدينة البيضاء، وتكون مجتمع من جميع طالبات كلية أصول الدين بمدينة البيضاء للعام الدراسي( 2019م ) وتراوحت أعمارهن بين (18 ـ 24 سنة فأكثر) ولقد تم تطبيق مقياس على عينة استطلاعية بلغت فيها ن= 120 طالبة من طالبات كلية أصول الدين، وذلك لاستخراج الخصائص السيكومترية للمقياس، وتكونت عينة الدراسة من الطالبات اللواتي يعانين شعورا بالوحدة النفسية وبلغ عددهن ن =30 طالبة، وتمثلت أدوات الدراسة في مقياس الشعور بالوحدة النفسية، وبرنامج الإرشاد المعرفي السلوكي، ولقد تم استخدام المجموعتين التجريبية والضابطة مع القياسيين القبلي والبعدي، وتم تطبيق الدراسة على مدار ثلاثة أيام في الأسبوع الأثنين والثلاثاء والخميس لمدة شهر ونص من فترة 15 / 11 / 2019م إلي 30 / 12 / 2019، وتم تطبيق البرنامج بقاعة كلية أصول الدين حيث تم تقسيم الطالبات إلى مجموعتين المجموعة التجريبية تضم (15) طالبة والمجموعة الضابطة تضم( 15) طالبة، وتم استخدامها خلال ثلاث عشرة جلسة ، يتراوح زمن كل جلسة ساعة واحدة وفق أهداف الجلسة، ولقد استخدام الأسلوب الإحصائي تحليل البيانات لحزمة الإحصائية SPSS واستخدم اختبار t لعينين غير مستقلتين وذلك لتحقيق التكافؤ وعشوائية التوزيع في المجموعتين .وتبين من تحليل البيانات النتائج التالية: لقد تم تفسير نتائج في ضوء الخلفية النظرية والدراسات السابقة واتضحت فعالية برنامج الإرشادي المعرفي السلوكي في خفض من حدة الشعور بالوحدة النفسية لدي طالبات كلية أصول الدين بجامعة السيد محمد بن علي السنوسي الإسلاميةـ 1 ـ يتضح أن أفراد العينة لديهم مستوى مرتفع من أعراض الشعور بالوحدة النفسية .2ـ الفروق غير دالة إحصائيا بين متوسطات المجموعة التجريبية والمجموعة الضابطة قبل تطبيق البرنامج .3ـ الفروق دالة إحصائيا بين متوسطات المجموعة التجريبية والمجموعة الضابطة بعد تطبيق البرنامج .4ـ الفروق دالة إحصائيا بين متوسطات أفراد المجموعة التجريبية في القياسات المتعددة (القبلي و البعدي والتابعي).
النظم التعليميّ في حاشية الخضريّ على ابن عقيل (دراسة وصفيّة تحليليّة)
Authors: عثمان د.عمر 
Published: June 2024

تعد حاشية الخضري على شرح ابن عقيل على ألفية ابن مالك في النحو من أهم الحواشي النحوية التي حظيت باهتمام الدارسين؛ لما فيها من إضافات علمية قيمة على مادة هذا الشرح الذي يعد أكثر شروح الألفية انتشارًا، وقد وظّف صاحب الحاشية عدة وسائل وأساليب علمية لتحقيق أهدافه من تأليف هذه الحاشية، من بينها النظم التعليمي الذي كان سائدًا في الأوساط التعليمية في تلك الحقبة.
وهذه الدراسة استهدفت الكشف عن منهج الخضريّ في توظيف النظم التعليميّ في حاشيته على شرح ابن عقيل على ألفية ابن مالك، حيث اعتمد الباحث خلالها المنهج الوصفي التحليليّ من خلال تتبع ما ورد من النظم التعليمي في متن الحاشية لحصر هذه المادة العلمية وتحليلها؛ بغية الوصول لملامح منهج المؤلف في توظيف هذه المنظومات التعليمية في توضيح مراد الناظم والشارح وإضافة ما يراه متمما للفائدة.
مشكلة الإسقاط وضبط أنظمة الإحداثيات المرتبطة بالخرائط الطبوغرافية والمرئيات الفضائية - دراسة كارتوغرافية – لوحتي البيضاء - بنغازي أنموذجا
Authors: رمضان علي سعد عادل 
Published: June 2024

تكمن أهمية موضوع الدراسة (مشكلات مطابقة المرئيات الفضائية مع الخرائط الطبوغرافية) في إجراء عمليات تطابق بين الخرائط الطبوغرافية المعدة وفق نظام كلارك 1880 والخرائط المعدة من الصور والبيانات الفضائية وفق نظام WGS84، ومحاولة الكشف عن طرق في تحديد المواقع للظواهر الجغرافية بين النظامين، حيث ان القيام بإجراء الجانب التطبيقي لنتائج التطابق يفيد في الحصول على أدق المواقع الممكنة لمعطيات السطح الأرضي ، وكذلك يفيد في البحث والاستقصاء عن أسباب عدم التطابق والفروقات الناتجة مع بيان نوع هذه الفروقات والتأثيرات المحتملة سواء للمسافات بين الظواهر أو لاختلافات مواقع خطوط الطول والعرض بين الخرائط الطبوغرافية والمرئيات الفضائية .
كذلك اعتمدت هذه الدراسة على نظم المعلومات الجغرافية (GIS) بوصفها وسيلة مهمة تعمل على ترتيب المعلومات وتصنيفها حسب الأهمية والحاجة وتطابقها مع مواقعها الحقيقية، وتتأكد أهمية نظم المعلومات الجغرافية من خلال وجود أنظمة وبرامج تقوم بإجراء عمليات تطابق البيانات لمصادر متعددة مثل الخرائط الطبوغرافية وبمقايس مختلفة والخرائط الكادسترالية والخرائط الموضوعية المعدة من الصور الجوية والبيانات الفضائية فضلا عن الخرائط المعدة والمشتقة من المرئيات الفضائية .
Sobrecarga del Cuidador Informal en paciente con Enfermedades Crónicas, en un Prestador Primario de Salud, Montería - Córdoba, 2023
Authors: Romero Ramos Julio Cesar , Hernández Bedoya Wendy Johana , Ramírez Hernández Cristian Andrés 
Published: June 2024

Introducción: Durante los últimos años con el progreso de la sociedad en todos los ámbitos, se ha presentado un aumento de la esperanza de vida y esto se ha acompañado de un cambio en las principales causas de muerte y un aumento de la prevalencia de ciertas patologías (enfermedades crónicas y discapacidades físicas y/o psíquicas), que condicionan cierto grado de dependencia, siendo los adultos mayores el grupo de la población más afectada. Objetivos: Identificar la sobrecarga del cuidador informal en paciente con enfermedades crónicas en un prestador primario de salud, Montería - Córdoba, 2023. Metodología: Estudio cuantitativo descriptivo de corte trasversal. Conto con 120 participantes, correspondientes a la muestra significativa de la población objeto de estudio. Previo consentimiento informado, se identificaron las características sociodemográficas y la sobrecarga del cuidador informal de pacientes con enfermedades crónicas. “Escala de sobrecarga del cuidador de Zarit (Caregiver Burde Interview)”. El análisis estadístico descriptivo permitió representar los datos en frecuencias y porcentajes. Resultados: Participaron 120 cuidadores informales: 77% mujeres y 23% hombres. El 69% era de áreas urbanas, el 31% de zonas rurales. Educación bachillerato 48.2% o técnica/superior (32.5%). Estado civil: solteros 36.6%, casados 31.8%, unión libre 26.6%. Amas de casa 42.5%, trabajadores independientes 27.5%, empleados 22.5%. Estrato I (80%), estrato II 20%. Cuidares hijos (58.3%) Esposo / a 15%. Horas al cuidado de 6-12 horas 52.5%. de 12 – 18 horas 25.8%. a nivel global de la sobrecarga del cuidador informal, es ausencia de sobrecarga con el 66%, seguido sobrecarga ligera con el 19%, y un 15% sobrecarga intensa. Conclusión: Los resultados permitieron cumplir los objetivos de estudio e identificar una correlación positiva entre las competencias del cuidar y la sobrecarga del cuidador informal, que se puede interpretar “a mayores competencias del cuidar menor el nivel de sobrecarga”. Estos hallazgos evidencian que el cuidador informal y prestador primario de salud tiene diversas competencias, además habilidades para ejercer de forma óptima sus roles de cuidadores y prestadores de servicios de salud y por ende tener la capacidad de afrontar situaciones de sobrecarga. La dependencia funcional del paciente crónico en su cuidador se estableció mediante el número de horas que emplea el cuidador informal a su cuidado donde existe relación una dependencia funcional del 79%.
The number of Estonian black fungus gnats (Diptera, Sciaridae) doubled: the first records of 64 species
Authors: Gorban Ina , Heller Kai , Kurina Olavi 
Published: June 2024

Adult sciarid flies are small to medium-sized, delicate insects, typically black in colour and belonging to the superfamily Sciaroidea within the order Diptera. They exhibit a uniform appearance. Distinguishing them from other families of Sciaroidea is primarily achieved through their typical wing venation. Sciaridae are common in both natural and semi-natural ecosystems, where they play a significant role in decomposition during their larval stage. Prior to the current study, only one specific research project had been conducted on Sciaridae in Estonia. The number of sciarid species identified in Estonia was set at 67.
This research, conducted in north-eastern Estonia during 2015 and 2016, presents a comprehensive overview of Sciaridae diversity, shedding light on previously understudied aspects of Estonia's biodiversity. A total of 1038 specimens were identified, representing 91 species, amongst which 64 were previously unknown to Estonia. Notably, Corynoptera winnertzi (Mohrig, 1993) emerged as the most abundant species, followed by Corynoptera irmgardis (Lengersdorf, 1930), Corynoptera crassistylata (Frey, 1948) and Bradysia trivittata (Staeger, 1840). The genus Corynoptera Winnertz, 1867 exhibited the highest diversity, consistent with findings from broader European studies. This study underscores the importance of ongoing surveys for better understanding the distribution and composition of Sciaridae species in Estonia, emphasising the need for further research to delve into the intricate ecology and biology of these insects.
Action of circulating and infiltrating B cells in the immune microenvironment of colorectal cancer by single-cell sequencing analysis
Authors: Zhang Jing-Po , Yan Bing-Zheng , Liu Jie , Wang Wei 
Published: June 2024

BACKGROUND
The complexity of the immune microenvironment has an impact on the treatment of colorectal cancer (CRC), one of the most prevalent malignancies worldwide. In this study, multi-omics and single-cell sequencing techniques were used to investigate the mechanism of action of circulating and infiltrating B cells in CRC. By revealing the heterogeneity and functional differences of B cells in cancer immunity, we aim to deepen our understanding of immune regulation and provide a scientific basis for the development of more effective cancer treatment strategies.
AIM
To explore the role of circulating and infiltrating B cell subsets in the immune microenvironment of CRC, explore the potential driving mechanism of B cell development, analyze the interaction between B cells and other immune cells in the immune microenvironment and the functions of communication molecules, and search for possible regulatory pathways to promote the anti-tumor effects of B cells.
METHODS
A total of 69 paracancer (normal), tumor and peripheral blood samples were collected from 23 patients with CRC from The Cancer Genome Atlas database (https://portal.gdc.cancer.gov/ ). After the immune cells were sorted by multicolor flow cytometry, the single cell transcriptome and B cell receptor group library were sequenced using the 10X Genomics platform, and the data were analyzed using bioinformatics tools such as Seurat. The differences in the number and function of B cell infiltration between tumor and normal tissue, the interaction between B cell subsets and T cells and myeloid cell subsets, and the transcription factor regulatory network of B cell subsets were explored and analyzed.
RESULTS
Compared with normal tissue, the infiltrating number of CD20+B cell subsets in tumor tissue increased significantly. Among them, germinal center B cells (GCB) played the most prominent role, with positive clone expansion and heavy chain mutation level increasing, and the trend of differentiation into memory B cells increased. However, the number of plasma cells in the tumor microenvironment decreased significantly, and the plasma cells secreting IgA antibodies decreased most obviously. In addition, compared with the immune microenvironment of normal tissues, GCB cells in tumor tissues became more closely connected with other immune cells such as T cells, and communication molecules that positively regulate immune function were significantly enriched.
CONCLUSION
The role of GCB in CRC tumor microenvironment is greatly enhanced, and its affinity to tumor antigen is enhanced by its significantly increased heavy chain mutation level. Meanwhile, GCB has enhanced its association with immune cells in the microenvironment, which plays a positive anti-tumor effect.
Sm-like 5 knockdown inhibits proliferation and promotes apoptosis of colon cancer cells by upregulating p53, CDKN1A and TNFRSF10B
Authors: Mo Cai-Jing , Deng Xiao-Yuan , Ma Ru-Lan , Zhu Kun , Shi Lei , Li Kang 
Published: June 2024

BACKGROUND
The role of Sm-like 5 (LSM5) in colon cancer has not been determined. In this study, we investigated the role of LSM5 in progression of colon cancer and the potential underlying mechanism involved.
AIM
To determine the role of LSM5 in the progression of colon cancer and the potential underlying mechanism involved.
METHODS
The Gene Expression Profiling Interactive Analysis database and the Human Protein Atlas website were used for LSM5 expression analysis and prognosis analysis. Real-time quantitative polymerase chain reaction and Western blotting were utilized to detect the expression of mRNAs and proteins. A lentivirus targeting LSM5 was constructed and transfected into colon cancer cells to silence LSM5 expression. Proliferation and apoptosis assays were also conducted to evaluate the growth of the colon cancer cells. Human GeneChip assay and bioinformatics analysis were performed to identify the potential underlying mechanism of LSM5 in colon cancer.
RESULTS
LSM5 was highly expressed in tumor tissue and colon cancer cells. A high expression level of LSM5 was related to poor prognosis in patients with colon cancer. Knockdown of LSM5 suppressed proliferation and promoted apoptosis in colon cancer cells. Silencing of LSM5 also facilitates the expression of p53, cyclin-dependent kinase inhibitor 1A (CDKN1A) and tumor necrosis factor receptor superfamily 10B (TNFRSF10B). The inhibitory effect of LSM5 knockdown on the growth of colon cancer cells was associated with the upregulation of p53, CDKN1A and TNFRSF10B.
CONCLUSION
LSM5 knockdown inhibited the proliferation and facilitated the apoptosis of colon cancer cells by upregulating p53, CDKN1A and TNFRSF10B.
Ferroptosis regulating lipid peroxidation metabolism in the occurrence and development of gastric cancer
Authors: Wang Lan-Mei , Zhang Wei-Wei , Qiu Ying-Yang , Wang Fang 
Published: June 2024

BACKGROUND
Gastric cancer is one of the most common malignant tumors in the world, and its occurrence and development involve complex biological processes. Iron death, as a new cell death mode, has attracted wide attention in recent years. However, the regulatory mechanism of iron death in gastric cancer and its effect on lipid peroxidation metabolism remain unclear.
AIM
To explore the role of iron death in the development of gastric cancer, reveal its relationship with lipid peroxidation, and provide a new theoretical basis for revealing the molecular mechanism of the occurrence and development of gastric cancer.
METHODS
The process of iron death in gastric cancer cells was simulated by cell culture model, and the occurrence of iron death was detected by fluorescence microscopy and flow cytometry. The changes of gene expression related to iron death and lipid peroxidation metabolism were analyzed by high-throughput sequencing technology. In addition, a mouse model of gastric cancer was established, and the role of iron death in vivo was studied by histology and immunohistochemistry, and the level of lipid peroxidation was detected. These methods comprehensively and deeply reveal the regulatory mechanism of iron death on lipid peroxidation metabolism in the occurrence and development of gastric cancer.
RESULTS
Iron death was significantly activated in gastric cancer cells, and at the same time, associated lipid peroxidation levels increased significantly. Through high-throughput sequencing analysis, it was found that iron death regulated the expression of several genes related to lipid metabolism. In vivo experiments demonstrated that increased iron death in gastric cancer mice was accompanied by a significant increase in lipid peroxidation.
CONCLUSION
This study confirmed the important role of iron death in regulating lipid peroxidation metabolism in the occurrence and development of gastric cancer. The activation of iron death significantly increased lipid peroxidation levels, revealing its regulatory mechanism inside the cell.
Correlation analysis of interstitial maturity and prognosis of colorectal cancer: Meta-analysis
Authors: Liu Zhen-Jun , Zhang Xu-Wen , Liu Qi-Qi , Wang Shao-Zhao 
Published: June 2024

BACKGROUND
To investigate the relationship between interstitial maturity and prognosis of colorectal cancer.
AIM
To examine the correlation between interstitial maturity and the prognosis of colorectal cancer.
METHODS
The paper database PubMed, EMBASE, Cochranelibrary, Springerlink, CNKI, and Wanfang database were searched until December 2023. "tumor stroma maturity" "desmoplastic stroma reaction" "desmoplastic reaction" "stroma reaction" "degree of stroma reaction "" stroma classification" "stroma density" "colorectal cancer" "colon cancer" "rectal cancer" "prognosis" were searched for the search terms. Two system assessors independently screened the literature quality according to the inclusion exclusion criteria, Quality evaluation and data extraction were performed for the included literatures, and meta-analysis was performed for randomized control trials included at using Review Manager 5.2 software.
RESULTS
Finally, data of 9849 patients with colorectal cancer from 19 cosets in 15 literatures were included, including 4339 patients with mature type (control group), 3048 patients with intermediate type (intermediate group) and 2456 patients with immature type (immature group). The results of meta-analysis showed: Relapse-free survival [hazard ratio (HR) = 2.66, 95% confidence interval (CI): 2.30-3.08; P < 0.00001], disease-free survival (HR = 3.68, 95%CI: 2.33-5.81; P < 0.00001) and overall survival (HR = 1.70, 95%CI: 1.53-1.87; P < 0.00001) were significantly lower than those in mature group (control group); relapse-free survival (HR = 1.36, 95%CI: 1.17-1.59; P < 0.0001) and disease-free survival rate (HR = 1.85, 95%CI: 1.53-2.24; P < 0.0001) was significantly lower than the mature group (control group).
CONCLUSION
There is the correlation between tumor interstitial maturity and survival prognosis of colorectal cancer, and different degrees of tumor interstitial maturity have a certain impact on the quality of life of colorectal cancer patients.
The photoprotective effectiveness of microemulsion gel made from an ethanol extract of kelakai root (Stenochlaena palustris (Brum. f) bedd.)
Authors: Forestryana Dyera , Ramadhan Hafiz , Maulida Puteri 
Published: June 2024

Background: Free radicals from sunlight have detrimental effects on the skin, such as black and dull colouration and dry- and easy-to-age skin. Prevention can be done by using antioxidants derived from plants as photoprotective. Kelakai root extract has a potent antioxidant activity of 19.06 ppm. Using typical preparations in the form of microemulsion gels protects the skin from free radicals.
Objective: This study aimed to determine the photoprotective effectiveness of the microemulsion gel preparation of kelakai root extract.
Method: The extraction method adopted maceration with 70% ethanol solvent. The microemulsion was incorporated into a gel dosage form with a concentration of 5%. The effectiveness of the photoprotective gel was measured using UV-Vis spectrophotometry, which included determining the value of the Sun Protector Factor (SPF), erythema transmission percentage (%Te), and pigmentation transmission percentage (%Tp).
Result: The results showed that the microemulsion gel of kelakai root extract with a concentration of 80 ppm had an SPF value of 9.816 with a %Te value of 9.591% and a %Tp value of 16.779%.
Conclusion: The microemulsion gel of the kelakai root extract has photoprotective effectiveness as a sunscreen in the sunblock category.
FORMAÇÃO DE PROFESSORES, NARRATIVAS DOCENTES ANALISADAS NO CURSO “LETRAMENTO LÚDICO E CRIATIVO PARA OS ANOS INICIAIS DA SEEDF”
Authors: Cardoso Almeida Nilvânia , Campos Machado Liliane 
Published: June 2024

Este trabalho resulta da análise do diário reflexivo do curso de formação de professores, “Letramento Lúdico e Criativo para os professores dos Anos Iniciais”, oferecido pela Secretaria de Estado de Educação do Distrito Federal – SEEDF no ano de 2015, por meio da Subsecretaria de Formação Continuada dos Profissionais em Educação (EAPE) e seus formadores regionais localizados na Coordenação Regional de Sobradinho - DF. O texto explora a formação de professores e as narrativas apresentadas pelos participantes durante o curso oferecido pela SEEDF. É uma produção de natureza qualitativa, com ênfase nas narrativas biográficas registradas no diário reflexivo desenvolvidos no processo formativo citado. A revisão de literatura pautou-se nos estudos de Frigotto; Ciavatta, (2003) e Souza (2006), Delory (2012), Matos e Souza (2015), Souza e Matos (2017), Larrosa (2002), os quais contribuíram para a compreensão das abordagens feitas a partir dos registros reflexivos dos cursistas em processo de formação. A contribuição desse processo formativo possibilitou a ressignificação da prática pedagógica a partir das narrativas apresentadas durante as rodas de conversas, em que a teoria e a prática foram articuladas no sentido de justificar a transformação da ação docente.

Palavras-chave: Educação. Formação de professores. Narrativas docentes.
Politik Hukum Pembatasan Penggunaan Kantong Plastik Sekali Pakai dalam Produk Hukum Daerah
Authors: Siregar Rajacia Angeline , Artina Dessy , Diana Ledy 
Published: June 2024

Introduction: Waste management in Pekanbaru City has received national attention because it is not handled properly. Pekanbaru City can produce 42 tons of plastic waste a day, which is around 20 percent of the total daily waste production.
Purposes of the Research: To understand the legal politics and ideal concept of regulating restrictions on the use of single-use plastic bags in regional legal products in the city of Pekanbaru.
Methods of the Research: The type of research used is normative legal research, namely using library research to search for data.
Results Originality of the Research: The research results show that Article 7 paragraph (1) of Pekanbaru Mayor Regulation Number 6 of 2023 concerning Reducing the Use of Plastic Bags is still not a solution in overcoming the problem of plastic waste in the city of Pekanbaru.
HEMS using Machine Learning and IoT in Energy Management
Authors: N. Sudha  , M. Santhiya  , S. Tamil Selvi  , R. Sathish  
Published: June 2024

The smart grid is a significant component of our modern networks and society. Smart metres are essential. A smart metre offers user engagement, automated information gathering, energy control, and instantaneous monitoring of dependable status. Additionally, it offers two ways for information to move between suppliers and customers, improving efficiency and control. In addition, it offers power management and real-time usage information. As long as the customer’s maximum load demand exceeds the maximum Value, the electricity supply to customers will be separated with the help of implementation of IOT based system for HEMS. In an ideal environment with normal workload conditions, the smart meter has a service life of 5 to 6 years. In this paper the use of the smart meter with IOT Technology is introduced. Many methods are recommended, such as the Energy Monitoring and Prediction System, which is an effective way to keep an eye on the gadgets that are used in homes or businesses. In this research, we have focused on estimating the electric energy consumption of household appliances in a low-energy consumption flat using a machine learning technique. In order to enable demand-side management and allow any legitimate consumer to view their individual consumption rate remotely, this paper focused on a smart system that wirelessly profiles energy consumption by calculating the facility consumed by each individual consumer. The calculated rate is then transmitted to a cloud web server.