bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Direct Decomposition of NO into N2 and O2 on C‐Type Cubic Y2O3—ZrO2 and Y2O3—ZrO2—BaO.
Authors: Tsujimoto Soichiro , Wang Xiaojing , Masui Toshiyuki , Imanaka Nobuhito 
Published: September 2011

AbstractC‐type cubic Y2O3 catalysts in which the Y3+ site is partially substituted by Zr4+ and Ba2+ are prepared by coprecipitation.
ChemInform Abstract: Synthesis and Crystal Structure of a Rare Tetra‐Yttrium‐Supported Krebs‐Type Tungstoantimonate.
Authors: Tan Rongxin , Pang Xiaohong , Ren Yulan , Wang Xiaohong , Li Rui 
Published: September 2011

AbstractNa2 [{Y(H2O) 7}4Sb2W22O76] ·14H2O is synthesized from an aqueous HNO3 solution of Y2O3 and Na9[SbW9O33], (pH 2.2 adjusted with 4 M HCl, 95 °C, 2 h, 50% yield).
ChemInform Abstract: Chiral Sc‐Catalyzed Asymmetric Michael Reactions of Thiols with Enones in Water.
Authors: Ueno Masaharu , Kitanosono Taku , Sakai Masaru , Kobayashi Shu 
Published: September 2011

AbstractUnder these conditions a number of organic sulfides can be prepared with good to high enantioselectivity.
ChemInform Abstract: Organocatalytic Enantioselective Formal Conjugate Addition of a Hydroxymoyl Anion to α,β‐Unsaturated Aldehydes.
Authors: Alonso Beatriz , Reyes Efraim , Carrillo Luisa , Vicario Jose L. , Badia Dolores 
Published: September 2011

AbstractThe method uses (II) as an excellent hydroxymethanimidoyl anion equivalent and a chiral secondary amine as organocatalyst.
ChemInform Abstract: Regioselective Addition of Organometallic Reagents to 2‐(1‐Alkynyl)‐2‐alken‐1‐ones for an Efficient Synthesis of Substituted 1,2‐Allenyl Ketones.
Authors: Yu Xiuzhao , Zhang Junliang 
Published: September 2011

AbstractThe allenyl ketones are useful synthons for tetrasubstituted allenes and highly substituted furans.
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Addition of Potassium Organotrifluoroborates to N‐Sulfonyl Ketimines.
Authors: Shintani Ryo , Takeda Momotaro , Soh Ying‐Teck , Ito Tomoaki , Hayashi Tamio 
Published: September 2011

AbstractThe nosyl group is easily removed under mild conditions with retaining the enantiomeric excess.
ChemInform Abstract: Convenient and Selective Hydrogenation of Nitro Aromatics with a Platinum Nanocatalyst under Ambient Pressure.
Authors: Xu Kunling , Zhang Yuan , Chen Xiaorong , Huang Lei , Zhang Rui , Huang Jun 
Published: September 2011

AbstractPt nanoparticles supported on a porous ionic copolymer (=PICP)(based on 1,1,3,3,‐tetramethylguanidium with CO32‐ anion) efficiently promote the transformation to anilines.
ChemInform Abstract: A New Class of Heterogeneous Platinum Catalyst for the Chemoselective Hydrogenation of Nitroarenes.
Authors: Pandarus Valerica , Ciriminna Rosaria , Beland Francois , Pagliaro Mario 
Published: September 2011

AbstractIt is found that Pt nanoparticles entrapped within an organosilica matrix efficiently promote the reduction of a wide range of nitroarenes to aromatic amines.
ChemInform Abstract: Palladium‐Catalyzed Aerobic Oxidative Direct Esterification of Alcohols.
Authors: Liu Chao , Wang Jing , Meng Lingkui , Deng Yi , Li Yao , Lei Aiwen 
Published: September 2011

AbstractThe challenging esterification reactions of long‐chain aliphatic alcohols are accomplished by using P‐olefin ligand to control the selectivity.
ChemInform Abstract: Organocatalytic Asymmetric Synthesis of Sulfoxides from Sulfenic Acid Anions Mediated by a Cinchona‐Derived Phase‐Transfer Reagent.
Authors: Gelat Fabien , Jayashankaran Jayadevan , Lohier Jean‐Francois , Gaumont Annie‐Claude , Perrio Stephane 
Published: September 2011

AbstractThe reaction can be scaled up and tolerates functional groups and steric hindrance in the aryl substituents.
ChemInform Abstract: In situ Generation of the Coates Catalyst: A Practical and Versatile Catalytic System for the Carbonylation of meso‐Epoxides.
Authors: Ganji Prasad , Doyle David J. , Ibrahim Hasim 
Published: September 2011

AbstractThe catalytic system is effective at low loading in the carbonylation of a variety of functionalized, sterically hindered and heterocyclic epoxides to yield β‐lactones.
ChemInform Abstract: An Efficient Approach to Fused Indolines via a Copper(I)‐Catalyzed Reaction of Sulfonyl Azide with 2‐Ethynylaryl Methylenecyclopropane.
Authors: Li Shaoyu , Luo Yong , Wu Jie 
Published: September 2011

AbstractThe reaction leads to various fused N‐sulfonyl indolines.
ChemInform Abstract: Novel 3‐Chlorooxazolidin‐2‐ones as Antimicrobial Agents.
Authors: Jain Rakesh K. , et al. et al. 
Published: September 2011

AbstractA series of 3‐chlorooxazolidin‐2‐one derivatives are synthesized and evaluated for their antimicrobial and cytotoxic activity.
ChemInform Abstract: Regioselective Synthesis of 1,2‐ vs. 1,3‐Squaraines.
Authors: Ronchi Elisabetta , Ruffo Riccardo , Rizzato Silvia , Albinati Alberto , Beverina Luca , Pagani Giorgio A. 
Published: September 2011

AbstractA method for the direct synthesis of the symmetrical and nonsymmetrical 1,2‐squarines is described.
ChemInform Abstract: Synthesis of Benzologues of Nitazoxanide and Tizoxanide: A Comparative Study of Their in vitro Broad‐Spectrum Antiprotozoal Activity.
Authors: Navarrete‐Vazquez Gabriel , Chavez‐Silva Fabiola , Argotte‐Ramos Rocio , Rodriguez‐Gutierrez Maria del Carmen , Chan‐Bacab Manuel Jesus , Cedillo‐Rivera Roberto , Moo‐Puc Rosa , Hernandez‐Nunez Emanuel 
Published: September 2011

AbstractTwo new annulated analogues (I) of the antiprotozoal agent nitazoxanide (NIT) and its metabolite tizoxanide (TIZ), are prepared using a short synthetic route.
ChemInform Abstract: Copper‐Mediated Annulative Direct Coupling of o‐Alkynylphenols with Oxadiazoles: A Dehydrogenative Cascade Construction of Biheteroaryls.
Authors: Hachiya Hitoshi , Hirano Koji , Satoh Tetsuya , Miura Masahiro 
Published: September 2011

AbstractThe construction of a wide range of benzofuran‐3‐yl‐1,3,4‐oxadiazole derivatives proceeds under conditions A).
ChemInform Abstract: New Quinolin‐4‐yl‐1,2,3‐triazoles Carrying Amides, Sulfonamides and Amidopiperazines as Potential Antitubercular Agents.
Authors: Thomas K. D. , Adhikari Airody Vasudeva , Chowdhury Imran H. , Sumesh E. , Pal Nishith K. 
Published: September 2011

AbstractAmong the synthesized compounds, compounds (IXa), (IXc)—(IXe), (XIc), (XVa) and (XVd) show significant antitubercular activity when compared to isoniazid.
ChemInform Abstract: Novel Regio‐ and Stereo‐Selectivity: Synthesis of Dihydropyrrolo[1,2‐f]phenanthridines via Isocyanide‐Based Multicomponent Reaction.
Authors: Li Ming , Qiu Zhong‐Xuan , Wen Li‐Rong , Zhou Zhong‐Min 
Published: September 2011

AbstractIn the absence of a catalyst, phenanthridine, malononitriles and isocyanides give the title compounds as single diastereomers or with high diastereoselectivity, depending on the bulkiness of the isocyanide.
ChemInform Abstract: A New Approach to the Synthesis of 4‐(N‐Aryl)carbamoylmethyl‐4,5‐dihydropyridazin‐3(2H)‐ones.
Authors: Stepakov Alexander V. , Kinzhalov Michail A. , Boitsov Vitaly M. , Stepakova Liubov V. , Starova Galina L. , Vyazmin Sergey Yu. , Grinenko Elena V. 
Published: September 2011

AbstractThe reaction of N‐aryl maleimides (II) with aliphatic ketazines (I), (VII), and (IX) leads to the formation of 4,5‐dihydropyridazin‐3‐ones (III), (VIII), and (X) in moderate yields.
ChemInform Abstract: Cyclocondensation of 2‐Iodobenzaldehyde with Benzamidines Catalyzed by Copper(I) Iodide: A Route to 2‐Arylquinazolines.
Authors: Vypolzov A. V. , Dar'in D. V. , Ryazanov S. G. , Lobanov P. S. 
Published: September 2011

Abstract2‐Arylquinazolines (III) are synthesized in good yields, whereas the use of 2‐bromobenzaldehyde (IV) affords low yields due to a competing reaction leading to dihydrotriazine (V).
ChemInform Abstract: Synthesis of 2‐Aziridinyl Phosphonates by Modified Gabriel—Cromwell Reaction and Their Antibacterial Activities.
Authors: Dogan Oezdemir , Babiz Hakan , Goezen Ayse Guel , Budak Songuel 
Published: September 2011

AbstractAll new title compounds (V) and (VII) show comparably moderate to good growth inhibitory activity in reference to ampicillin and streptomycin.
ChemInform Abstract: 1,4‐Addition of Tetraethyl Fluoromethylenebisphosphonate to α,β‐Unsaturated Compounds.
Authors: Opekar Stanislav , Beier Petr 
Published: September 2011

AbstractOptimum reaction conditions are examined for the addition of tetraethyl fluoromethylenebisphosphonate (I) to α,β‐unsaturated compounds of type (II) or (IV).
ChemInform Abstract: Citrinin Derivatives from the Marine‐Derived Fungus Penicillium citrinum.
Authors: Chen Li , Liu Wei , Hu Xiao , Huang Kai , Wu Jiu‐Lin , Zhang Qi‐Qing 
Published: September 2011

AbstractIsolation and structure elucidation of three new citrinin derivatives, penicitrinol C‐E, along with two known citrinin derivatives are described.
ChemInform Abstract: 2‐Arylimidazo[2,1‐b]benzothiazoles: A New Family of Amyloid Binding Agents with Potential for PET and SPECT Imaging of Alzheimer′s Brain.
Authors: Alagille David , DaCosta Herve , Baldwin Ronald M. , Tamagnan Gilles D. 
Published: September 2011

AbstractA novel series of amyloid binding agents based on a 2‐aryl‐imidazo[2.1‐b]benzothiazole (I) scaffold are designed and synthesized.
ChemInform Abstract: Synthesis and Characterization of Single‐Crystalline MnFe2O4 Ferrite Nanocrystals and Their Possible Application in Water Treatment.
Authors: Wang Ying‐Qi , Cheng Rong‐Min , Wen Zi , Zhao Li‐Jun 
Published: September 2011

AbstractMnFe2O4 nanospheres and nano‐octahedra with a narrow size distribution are solvothermally synthesized from mixtures of FeSO4, KMnO4, NaOH, N2H4·H2O, and ethylene glycol (autoclave, 260 °C, 24 h).
ChemInform Abstract: Revisiting Glitazars: Thiophene Substituted Oxazole Containing α‐Ethoxy Phenylpropanoic Acid Derivatives as Highly Potent PPARα/γ Dual Agonists Devoid of Adverse Effects in Rodents.
Authors: Raval Preeti , et al. et al. 
Published: September 2011

AbstractIn an effort to develop safe and efficacious compounds for the treatment of metabolic disorders, novel thiophene substituted oxazole derivatives containing α‐alkoxy‐phenylpropanoic acid (I) are designed and synthesized as highly potent PPARα/γ dual agonists.
Bulky melamine‐based Zn‐porphyrin tweezer as a CD probe of molecular chirality
Authors: Petrovic Ana G. , Vantomme Ghislaine , Negrón‐Abril Yashira L. , Lubian Elisa , Saielli Giacomo , Menegazzo Ileana , Cordero Roselynn , Proni Gloria , Nakanishi Koji , Carofiglio Tommaso , Berova Nina 
Published: September 2011

AbstractThe transfer of chirality from a guest molecule to an achiral host is the subject of significant interest especially when, upon chiral induction, the chiroptical response of the host/guest complex can effectively report the absolute configuration (AC) of the guest. For more than a decade, dimeric metalloporphyrin hosts (tweezers) have been successfully applied as chirality probes for determination of the AC for a wide variety of chiral synthetic compounds and natural products. The objective of this study is to investigate the utility of a new class of melamine‐bridged Zn‐porphyrin tweezers as sensitive AC reporters. A combined approach based on an experimental CD analysis and a theoretical prediction of the prevailing interporphyrin helicity demonstrates that these tweezers display favorable properties for chiral recognition. Herein, we discuss the application of the melamine‐bridged tweezer to the chiral recognition of a diverse set of chiral guests, such as 1,2‐diamines, α‐amino‐esters and amides, secondary alcohols, and 1,2‐amino‐alcohols. The bulky periphery and the presence of a rigid porphyrin linkage lead, in some cases, to a more enhanced CD sensitivity than that reported earlier with other tweezers. Chirality, 2011. © 2011 Wiley‐Liss, Inc.
Reversible human serum albumin binding of lipocrine: A circular dichroism study
Authors: Bertucci Carlo , De Simone Angela , Pistolozzi Marco , Rosini Michela 
Published: September 2011

AbstractLipocrine has been selected as an effective candidate for in vivo investigation because of its multiple biological properties, namely inhibition of AChE and BChE activities, inhibition of AChE‐induced Aβ aggregation, and ability to protect cells against reactive oxygen species. To evaluate the possibility for lipocrine to become a lead and to be developed as a multipotent drug for the treatment of Alzheimer's disease, ADMET (absorption, distribution, metabolism, excretion, and toxicity) parameters need to be determined. Among ADMET parameters, distribution plays a key role in determining the lead drugability, and the drug binding to plasma proteins greatly influences the drug distribution. Here, the human serum albumin (HSA) binding of lipocrine has been studied by circular dichroism (CD) spectroscopy. The reversible binding of lipocrine is stereoselective as shown by the well‐defined induced CD spectrum in its binding to HSA. The intensity of the CD signal changes upon changing the [drug]/[HSA] molar ratio, showing a different behavior for a [drug]/[HSA] up to 2/1 or over this molar ratio, suggesting a binding to multiple sites. Competition experiments show that lipocrine interacts significantly with all the main binding sites on the serum carrier. A direct competition has been monitored for site II and bilirubin‐binding site, whereas a noncooperative binding should better describe the displacement observed at site I. Rac‐lipocrine and its enantiomers are characterized by two different binding modes. Almost the same induced CD spectra were obtained for both (R)‐ and (S)‐lipocrine complexed to HSA, suggesting a similar stereochemistry for the bound enantiomers. Chirality, 2011. © 2011 Wiley‐Liss, Inc.
Heat transfer in a fluid through a porous medium over a permeable stretching surface with thermal radiation and variable thermal conductivity
Authors: Cortell Rafael 
Published: September 2011

AbstractThis paper treats about the flow and heat transfer of a viscous incompressible fluid in a porous medium over a permeable stretching surface taking into account thermal radiation and the variation of the thermal conductivity with temperature. Analytical solutions for the stream function are obtained and two cases are studied, namely, (i) prescribed surface temperature (PST case) and (ii) prescribed heat flux (PHF case). The effects of Prandtl number, permeability, suction/blowing, variable thermal conductivity, thermal radiation and surface temperature parameters on heat‐transfer characteristics are shown through tables and graphs and discussed.Ce document concerne l´écoulement et le transfer de chaleur dans le cas d´un fluide visqueux incompressible dans un milieu poreux sur une poreux surface s´étendant en tenant compte de la radiation thermique et de la conductivité thermodépendante. Les solutions analytiques pour la fonction de courant sont obtenus et deux conditions à la frontière pour la tempèrature et le flux de chaleur sont apliquées: (i) predicted surface tempèrature (PST) et (ii) le flux de chaleur predicted (PHF). Les effects du nombre de Prandtl, perméabilité, succion/soufflage, conductivité thermodépendante, radiation thermique et de la surface tempèrature sur le transfer de chaleur sont indiqués dans des tableaux et des graphiques, puis sont discutés. © 2011 Canadian Society for Chemical Engineering
Yield stress of oxide dispersions—intermolecular forces of adsorbed small ionic additives and particle surface roughness
Authors: Ong B. C. , Leong Y. K. 
Published: September 2011

AbstractThe yield stress‐pH and zeta potential‐pH behaviour of α‐alumina and zirconia dispersions with adsorbed small ionic molecular additives such as phosphate and pyrophosphate were determined. The result for adsorbed citrate was included for comparison. Adsorbed phosphate at high surface coverage increased the maximum yield stress of low surface area α‐Al2O3 (AKP30 and AA07) dispersions slightly. This increase is attributed to the intermolecular hydrogen bonding between phosphates adsorbed on interacting particles. With high surface area ZrO2 (Tosoh) dispersions, however, the adsorbed phosphate decreased the maximum yield stress. This is due to its very rough surface morphology limiting the extent of intermolecular hydrogen bonding between adsorbed phosphate layers. Unlike phosphate, pyrophosphate reduces the maximum yield stress of AKP30 α‐Al2O3. This is due to the presence of intramolecular hydrogen bonding, thereby impeding effective bridging. A similar result is observed with citrate. The adsorbed pyrophosphate acts as an effective steric barrier keeping interacting particles further apart, thereby weakening the van de Waals attraction. These dispersions with the presence of non‐DLVO forces, that is bridging and steric, did not affect the linear relationship between yield stress and the square of the zeta potential as predicted by the yield stress–DLVO force model. However the relative importance of these non‐DLVO forces affect the value of the critical zeta potential at the point of transition from flocculated to dispersed state. © 2011 Canadian Society for Chemical Engineering
Combined effects of internal heat generation and higher order chemical reaction on the non‐darcian forced convective flow of a viscous incompressible fluid with variable viscosity and thermal conductivity over a stretching surface embedded in a porous medium
Authors: Rahman M. M. 
Published: September 2011

AbstractIn this paper, we study the combined effects of internal heat generation and higher order chemical reaction on a steady two‐dimensional non‐Darcian forced convective flow of a viscous incompressible fluid with variable dynamic viscosity and thermal conductivity in a fluid saturated porous medium passing over a linear stretching sheet. Using similarity transformations, the governing nonlinear‐coupled partial differential equations are made dimensionless and solved numerically for similarity solutions using very robust computer algebra software Maple 8. The non‐dimensional velocity, temperature and concentration distributions are presented graphically for various pertinent parameters such as relative temperature difference parameter, Darcy number, porosity parameter, reaction rate parameter and the order of the chemical reaction. The variations of Prandtl number and Schmidt number within the boundary layer are also displayed graphically when the fluid dynamic viscosity and thermal conductivity are temperature dependent. From the present numerical computations it is found that Prandtl number as well as Schmidt number must be taken as variables within the flow domain when the fluid's dynamic viscosity and thermal conductivity are variable. In the presence of internal heat generation, dynamic viscosity and thermal conductivity of the fluid are found to be higher than when it is absent. Increasing Darcy number reduces dynamic viscosity as well as thermal conductivity whereas increasing pore size reduces the Schmidt number and increases the Prandtl number within the boundary layer. For higher order reaction the rate of increase in mass transfer function is less compared to the rate of increase for the lower order reaction. © 2011 Canadian Society for Chemical Engineering
Incidence of subsequent pancreatic adenocarcinoma in patients with a history of nonpancreatic primary cancers
Authors: Amin Sunil , McBride Russell B. , Kline Jennie K. , Mitchel Elana B. , Lucas Aimee L. , Neugut Alfred I. , Frucht Harold 
Published: September 2011

AbstractBACKGROUND:Several environmental risk factors are known to predispose individuals to pancreatic cancer, and up to 15% of pancreatic cancers have an inherited component. Understanding metachronous cancer associations can modify pancreas cancer risk. The objective of this study was to investigate the association of nonpancreatic cancers with subsequent pancreatic adenocarcinoma.METHODS:The authors used data from the US Surveillance, Epidemiology, and End Results (SEER) registries to identify 1,618,834 individuals who had a primary malignancy and subsequent pancreatic adenocarcinoma (n = 4013). Standardized incidence ratios were calculated as an approximation of relative risk (RR) for the occurrence of pancreatic adenocarcinoma after another primary malignancy.RESULTS:Among patients who were diagnosed with a first primary malignancy at ages 20 to 49 years, the risk of subsequent pancreatic adenocarcinoma was increased among patients who had cancers of the ascending colon (relative risk [RR], 4.62; 95% confidence interval [CI], 1.86‐9.52), hepatic flexure (RR, 5.42; 95% CI, 1.12‐15.84), biliary system (RR, 13.14; 95% CI, 4.27‐30.66), breast (RR, 1.32; 95% CI, 1.09‐1.59), uterine cervix (RR, 1.61; 95% CI, 1.02‐2.41), testes (RR, 2.78; 95% CI, 1.83‐4.05), and hematopoietic system (RR, 1.83; 95% CI, 1.28‐2.53). Among patients who had a first malignancy at ages 50 to 64 years, the risk was increased after cancers of the stomach (RR, 1.88; 95% CI, 1.13‐2.93), hepatic flexure (RR, 2.25; 95% CI, 1.08‐4.13), lung and bronchus (RR, 1.46; 95% CI, 1.16‐1.82), pharynx (RR, 2.26; 95% CI, 1.13‐4.04), and bladder (RR, 1.24; 95% CI, 1.03‐1.48). Among patients who had a primary cancer after age 65 years, the risk was increased after cancers of the stomach (RR, 1.79; 95% CI, 1.23‐2.53), hepatic flexure (RR, 1.76; 95% CI, 1.06‐2.75), biliary system (RR, 2.35; 95% CI, 1.17‐4.20), and uterus (RR, 1.23; 95% CI, 1.03‐1.47).CONCLUSIONS:The results from the current population‐based data set suggested that pancreatic adenocarcinoma is associated with certain primary cancers. Genetic predisposition and common environmental and behavioral risk factors all may contribute to this observation. Specific tumor associations will guide future risk‐stratification efforts. Cancer 2012. © 2011 American Cancer Society.
Early versus delayed autologous transplantation after immunomodulatory agents‐based induction therapy in patients with newly diagnosed multiple myeloma
Authors: Kumar Shaji K. , Lacy Martha Q. , Dispenzieri Angela , Buadi Francis K. , Hayman Suzanne R. , Dingli David , Gay Francesca , Sinha Shirshendu , Leung Nelson , Hogan William , Rajkumar S. Vincent , Gertz Morie A. 
Published: September 2011

AbstractBACKGROUND:Early versus delayed autologous stem cell transplantation (SCT) results in comparable overall survival in patients with multiple myeloma (MM) who receive alkylator‐based therapies. It is not clear whether this paradigm holds true in the context of new therapies, such as immunomodulatory drugs (IMiDs).METHODS:The authors studied 290 patients with untreated MM who received IMiD‐based initial therapy, including 123 patients who received thalidomide‐dexamethasone (TD) and 167 patients who received lenalidomide‐dexamethasone (LD) induction before SCT. Patients who underwent a stem cell harvest attempt were considered transplantation‐eligible and were included. SCT within 12 months of diagnosis and within 2 months of harvest were considered early SCT (n = 173; 60%). SCT >12 months after diagnosis was considered delayed SCT (n = 112; 40%).RESULTS:In the delayed SCT group, 42 patients had undergone SCT at the time of the current report, and the median estimated time to SCT was 5.3 months and 44.5 months in the early SCT and delayed SCT groups, respectively. The 4‐year overall survival rate from diagnosis was 73% in both groups (P = .3) and was comparable in those who received TD (68% vs 64%, respectively) and those who received LD (82% vs 86%, respectively) as initial therapy. The time to progression after SCT was similar between the early and delayed SCT groups (20 months vs 16 months; P value nonsignificant).CONCLUSIONS:The current results indicated that, in transplantation‐eligible patients who receive IMiDs as initial therapy followed by early stem cell mobilization, delayed SCT results in similar overall survival compared with early SCT. It is noteworthy that an excellent 4‐year survival rate of >80% was observed among transplantation‐eligible patients who received initial therapy with LD regardless of the timing of transplantation. Cancer 2011;. © 2011 American Cancer Society.