bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of trauma quality improvement program implementation on mortality: A nonrandomized controlled trial
Authors: Berg Johanna , David Siddarth , Bakhshi Girish D. , Basak Debojit , Chatterjee Shamita , Soni Kapil Dev , Ekelund Ulf , Felländer-Tsai Li , Joshipura Manjul , Khan Tamal , Khajanchi Monty , L N Mohan , Mishra Anurag , Petzold Max , Rajan Sendhil , Roy Nobhojit , Singh Rajdeep , Wärnberg Martin Gerdin 
Published: May 2024

AbstractImportanceTrauma causes over four million deaths annually, predominantly in low- and middle-income countries. Implementing trauma quality improvement programs may improve outcomes, and though extensively used, high-quality evidence of their effectiveness is scarce.AimTo assess if implementing a trauma quality improvement program using on audit filters improves trauma patients’ outcomes.DesignA controlled interrupted time-series study.SettingProspective, multicenter study across four tertiary care hospitals in urban India between 2017-2022.ParticipantsAdult patients admitted to participating hospitals with history a of trauma, defined as having any of the external causes listed in block V01-Y36, chapter XX of the ICD-10 as reason for admission.InterventionIn the intervention arm (two hospitals), a trauma quality improvement program using audit filters was implemented after a one-year observation period. The control arm (two hospitals) continued baseline data collection without intervention throughout the study period.Main outcomesAll-cause mortality (in-hospital and at 30 days). For time series analysis, segmented regression with a generalized additive model (GAM) assessed the effect on in-hospital mortality. Secondary analysis using difference-in-differences and linear regression assessed in-hospital and 30-day mortality. The study was not powered for time series analysis on 30-day mortality.ResultsWe included 10143 patients, median age 35 (IQR 26 – 50), 83% men and found a crude 8% reduction(95% CI -11% to -5.3%, p<0.001)in in-hospital mortality and 14% reduction(95% CI -18% to -9.6%, p<0.001)in 30-day mortality in the intervention arm. Using time series analysis, we observed a significant reduction in in-hospital mortality(32% vs 24%; OR 0.56, 95% CI 0.4-0.77, p<0.001)in the intervention arm, with no significant change in the control arm. Difference-in-differences analysis found a significant reduction in 30-day mortality(39% vs 26%; DiD estimate -0.15 95% CI -0.19 to -0.11, p<0.001)and in-hospital mortality(32% vs 24%; DiD estimate -0.12 95% CI -0.16 to -0.09, p<0.001). However, external factors such as the opening of a dedicated trauma center at one intervention hospital and the COVID-19 pandemic may have influenced these results.ConclusionImplementing a trauma quality improvement program using audit filters may reduce mortality. More research is needed to confirm these findings across different settings and to understand by which mechanisms these programs mediate the effect and ensure sustainability in terms of improving outcomes.Trial registrationTrauma Audit Filter Trial, ClinicalTrials.gov IDNCT03235388,https://clinicaltrials.gov/study/NCT03235388
Age-related differences in rejection rates, infections and tacrolimus exposure in pediatric kidney transplant recipients – a benchmark study of the CERTAIN registry
Authors: Baghai Arassi Maral , Feißt Manuel , Krupka Kai , Awan Atif , Benetti Elisa , Duzova Ali , Guzzo Isabella , Kim Jon Jin , König Sabine , Litwin Mieczysław , Oh Jun , Bücher Anja , Pape Lars , Peruzzi Licia , Shenoy Mohan , Testa Sara , Weber Lutz T. , Zieg Jakub , Höcker Britta , Fichtner Alexander , Tönshoff Burkhard 
Published: May 2024

AbstractBackgroundData on age-related differences in rejection rates, infectious episodes and tacrolimus exposure in pediatric kidney transplant recipients (pKTR) on a uniform tacrolimus-based immunosuppressive regimen are scarce.MethodsWe therefore performed a large-scale analysis of 802 pKTR from the CERTAIN registry from 40 centers in 14 countries. Inclusion criteria were a tacrolimus-based immunosuppressive regimen and at least two years of follow-up. The patient population was divided into three age groups (infants <6 years, school-aged children 6-12 years, and adolescents >12 years) to assess age-related differences in outcome.ResultsMedian follow-up was 48 months (IQR, 36-72). Within the first 2 years post-transplant, infants had a significantly higher incidence of infections (80.6% vs. 55.0% in adolescents, P<0.001) and a significantly higher number of cumulative hospital days (median 13 days vs. 7 days in adolescents, P < 0.001). Adolescents had a significantly higher rate of biopsy-proven acute rejection episodes in the first year post-transplant (21.7%) than infants (12.6%, P=0.007). Infants had significantly lower tacrolimus trough levels, lower concentration-to-dose ratios as an approximation for higher tacrolimus clearance, and higher intra-patient variability (all P < 0.01) than adolescents.ConclusionsThis largest study to date in European pKTR on a tacrolimus-based immunosuppressive regimen shows important age-related differences in rejection rates, infection episodes, tacrolimus exposure and clearance. These data suggest that immunosuppressive therapy in pKTR should be tailored according to the age-specific risk profiles of this heterogeneous patient population.
Sickle hemoglobinopathy research in Zimbabwe and Zambia (SHAZ): Protocol for setting up an international Sickle Cell Disease registry
Authors: Kuona Patience , Kandawasvika Gwendoline Q , Chunda-Liyoka Catherine , Ruredzo Ian M , Sambo Pauline M , Gorejena-Chidawanyika Pamela , Mantina Hamakwa M , Mtisi Takudzwa J , Phiri Cynthia , Chikara Lawson , Kaweme Natasha M , Chivige Exavior , Namushi Jombo , Maborekeke Tendai , Uthale Uma H , Masimirembwa Collen 
Published: May 2024

AbstractOf the 500 000 children born with sickle cell disease annually, most cases occur in Africa, contributing to significant morbidity and mortality associated with limited sickle cell disease (SCD) health outcomes data and reduced access to therapeutic plus preventive care. We aim to develop and manage a standardized electronic SCD registry, establish consistent standards of care (SoC) for patients, improve the SCD research and biobanking capacity in Zimbabwe and Zambia. This five-year program employs mixed methods that include infrastructure and skilled manpower capacity building of SCD clinics, registry, biobanking, cohort and implementation science research studies to improve SCD treatment outcomes. We are collaborating with the SickleInAfrica consortium (Ghana, Mali, Nigeria, Tanzania, Uganda, and South Africa), the African Institute of Biomedical Sciences and Technology (AiBST) and St Jude’s Children Research Hospital. We established the SCD registry in Zimbabwe and Zambia for children and adult patients enrolling 1796/4000 (45%) participants to date. We are participating in SickleInAfrica consortium research activities, training health workers and educating SCD patient communities on SoC. This collaboration with African researchers, policymakers, health workers, and SCD patient communities will improve uptake of SCD SoC and increase our research capacity.
The four frames of leadership and motivating language theory: Version 2.0
Authors: Holmes William T. 
Published: May 2024

Purpose
The purpose of this conceptual paper is to increase the clarity and application of the original model and integration table. Specifically, the intent was to increase clarity by highlighting elements left out of the original article (sentence frames), adding additional information on the medium of leadership practice through the addition of Bolman and Deal's leadership lessons, and improving the flow and structure of leader steps as leaders move across the model in the leader sequence of events. Finally, the model was tweaked to adjust the political frame across both direction-giving and empathetic language based on participant feedback and a literature review.

Design/methodology/approach
The approach of this conceptual paper is to continue the evolution of the integration of the Four-Frames and Motivating Language Theory (MLT) first presented in DLO in 2019 using updated literature from Bolman and Deal (2019, 2021) and feedback from real-world implementation of the contents from the original article.

Findings
The findings of this conceptual paper are in two forms. First, the Version 2.0 integration model illustrates greater clarity and an improved sequence for implementation by leaders to address the pressing issues they face. Second, the illustration of the sentence frames and their evolution from the original article (2019) to the current paper highlights the power and integration of the Four-Frames and Motivating Language Theory regarding their versatility and utilization as a critical thinking and teaching tool for leaders and organizations.

Practical implications
For practitioners, this conceptual paper provides additional information on how to implement the Four-Frames as leaders through the power and influence of leadership communication and action.

Originality/value
The value of the Version 2.0 integrated model continues to leverage the combination of the Four Frames and Motivating Language Theory, which is still unique in the research. This evolution of the integration creates greater clarity in terms of understanding and utilizing leadership, connecting and sequencing the Four-Frames and MLT together, and applying the Four-Frame(s) accurately. This article continues to extend the field of Motivating Language Theory and addresses a gap in the work of the Four Frames – communication.
Returns from herding as a function of the social network of agents: a simulation study
Authors: Hazarika Ishan Kashyap , Yadav Ashutosh 
Published: May 2024

PurposeThis study combines different perspectives on herding, viewing it as a social network heuristic in comparison to other heuristics. The purpose is to use the heuristic view of herding as found in early literature and test it on grounds of efficiency and payoff, in essence, combining the heuristic and rational agent view of herding. The simulated double auction setting includes agents embedded in a social network, allowing for an examination of herding alongside rational behaviour and imperfect signals.Design/methodology/approachIn each round of the simulation, levels of homophily, density and fractions of types of agents is set and agents are allowed to follow their respective heuristics under those conditions. Characteristics of the social network, such as the size, levels of different homophilies, density and fractions of different types of agents are varied randomly to gauge their effect on the performance of herders vis-à-vis others and the overall market efficiency through simulation based approach. The data used for the study has been developed in Python and linear models are estimated using R.FindingsHerding decreases total surplus in private value double auctions, but herders are not worse off than other agents and perform equally in common value auctions. Further, herders and random offerers reduce payoffs of other agents as well, and herding effects the surplus per transaction and not the quantum.Research limitations/implicationsThis study explores herding as a strategic behaviour coexisting with rationality and other strategies in specific circumstances. It presents intriguing findings on the impact of herding on individual outcomes and market efficiency, raising new avenues for future research. Implication to research includes a dent on the “sieve” argument of markets rooting out irrationality and from it, a policy implication that follows is the need for corrective measures as markets cannot self-correct this, given herders do not perform worse than others.Originality/valueThe study links the phenomenon of herding to the dynamics of social networks and heuristic-based learning mechanisms that sets apart this research from the majority of existing literature, which predominantly conceptualizes herding as an outcome derived from a perfect Bayesian Equilibrium and a rational learning process.
Three research method approaches: musharaka financing performance model in Indonesian Islamic banks
Authors: Roziq Ahmad , Shulthoni Moch , Anugerah Eza Gusti , Mawardi Ahmad Ahsin Kusuma , Prasetyo Whedy 
Published: May 2024

Purpose
This paper aims to create a model of musharaka financing performance and Islamicizing agency theory to explain issues related to musharaka financing and propose solutions to these problems.

Design/methodology/approach
This research focuses on Islamic banks located in East Java Province, Indonesia, as the population for investigation. This study used primary data collected through a questionnaire instrument. The research adopts a mixed method approach, integrating quantitative data using the smartPLS program, qualitative data using a case study and kasyif research.

Findings
This research revealed that employee competence, Islamic business ethics and monitoring significantly impact the risk of musharaka financing. In contrast, information asymmetry does not significantly influence the risk of musharaka financing in Islamic banks. On the contrary, information asymmetry, Islamic business ethics and monitoring significantly affect the performance of musharaka financing. However, employee competence and risk of musharaka financing do not significantly influence the performance of musharaka financing in Islamic banks.

Research limitations
The responses to the questionnaire are analyzed from the perspective of directors and financing managers of Islamic banks who possess expertise in management and act as financing providers. However, musharaka partners who receive financing may have different perceptions and experiences of implementing musharaka financing.

Practical implications
Financing managers and directors at Islamic banks need to minimize the risk of musharaka financing and alleviate information asymmetry by enhancing employee competence and selecting musharaka partners capable of adhering to Islamic business ethics.

Social implications
Partners of musharaka financing should enhance their Islamic business ethics. Next, other researchers should improve this study by expanding the research locations, increasing the sample size, incorporating additional variables and involving musharaka partners as respondents.

Originality/value
It is a new research using three methods to construct a model of musharaka financing performance. The research refines agency theory by integrating Islamic values into Sharia agency theory.
Decoding digital engagement: a comparative analysis of English and Turkish brand post popularity dynamics on platform X
Authors: Tanaltay Altug , Ozturkcan Selcen , Kasap Nihat 
Published: May 2024

PurposeThis research aims to understand the dynamics that drive consumer engagement of multinational brands' social media posts on platform X, formerly known as Twitter. Taking the emotional tone of posts into account, the effect of vivid, interactive, informative, entertaining and practical features of posts on consumer interactions are evaluated across English- and Turkish-speaking markets.MethodologyInspired by the conceptual framework proposed in previous literature, features were extracted computationally using natural language processing from platform X posts of 33 Fortune 500 brands from various industries from June 2016 to June 2021. Following evaluation of regression models on alternative distributions of the dependent variable, which is total number of likes, shares and comments, random subspace regression using bootstrap resampling was applied to calculate an importance score and evaluate the effect of features.FindingsConsumers in English- and Turkish-speaking markets perceive and engage with content differently. While informative and entertaining posts resonate more with English speakers, emotions play a broader role for Turkish speakers. English-speaking audience prefers happy and vivid daytime messages with questions, while Turkish-speaking audience is drawn to angry messages, lean toward nighttime posts.OriginalityThis research is a pioneer to evaluate the factors that influence brands' platform X post engagements across markets of different cultural orientation. Beyond assessing the distinctions in brand post elements, the role of emotional content in brand messages were also analyzed across English- and Turkish-speaking markets.
Management interventions in pacing a planned financial accounting outsourcing transition
Authors: Flinkman Arja , Gullkvist Benita , Teittinen Henri 
Published: May 2024

Purpose
This paper aims to explore how the time and temporal aspects are managed in a financial accounting outsourcing (FAO) transition process in an international interorganizational context. As a research outcome, the authors identify management interventions of both the service provider (SP) and the outsourcing company (OC) at both the corporate and operational levels.

Design/methodology/approach
The framework by Huy (2001a, 2001b) was used to analyze the qualitative data, which draw on observations, participation in 32 official meetings during the outsourcing process, informal discussions with key actors from the SP and the OC, and archival data of a single case company.

Findings
The authors illustrate how the time and temporal aspects of planned accelerated change are managed through management interventions during the FAO transition process. All four ideal intervention types (commanding, engineering, teaching and socializing) were used sequentially but also jointly to complement one another. The pacing was mostly rapid, owing to strong commanding interventions initiating almost every stage. When analyzing the FAO transition process, the authors identified four stages: contact, contract, convergence and control. Moreover, the authors focused on the role of the operational-level managers and accounting specialists of both organizations. The findings indicate that management interventions vary with the management level.

Originality/value
This study contributes to the interorganizational control literature by considering the time and temporal aspects in planned organizational change and the role of operational-level managers in managing large-scale changes.
The impact of Medicaid expansion on state expenditures through the COVID‐19 era
Authors: Markell Jenny , Meiselbach Mark Katz 
Published: May 2024

AbstractObjectiveTo investigate the impact of Medicaid expansion on state expenditures through the end of 2022.Data SourcesWe used data from the National Association of State Budget Officers (NASBO)'s State Expenditure Report, Kaiser Family Foundation (KFF)'s Medicaid expansion tracker, US Bureau of Labor Statistics data (BLS), US Bureau of Economic Analysis data (BEA), and Pandemic Response Accountability Committee Oversight (PRAC).Study DesignWe investigated spending per capita (by state population) across seven budget categories, including Medicaid spending, and four spending sources. We performed a difference‐in‐differences (DiD) analysis that compared within‐state changes in spending over time in expansion and nonexpansion states to estimate the effect of Medicaid expansion on state budgets. We adjusted for annual state unemployment rate, annual state per capita personal income, and state spending of Coronavirus Relief Funds (CRF) from 2020 to 2022 and included state and year fixed effects.Data Collection/Extraction MethodsWe linked annual state‐level data on state‐reported fiscal year expenditures from NASBO with state‐level characteristics from BLS and BEA data and with CRF state spending from PRAC.Principal FindingsMedicaid expansion was associated with an average increase of 21% (95% confidence interval [CI]: 16%–25%) in per capita Medicaid spending after Medicaid expansion among states that expanded prior to 2020. After inclusion of an interaction term to separate between the coronavirus disease (COVID) era (2020–2022) and the prior period following expansion (2015–2019), we found that although Medicaid expansion led to an average increase of 33% (95% CI: 21%–45%) in federal funding of state expenditures in the post‐COVID years, it was not significantly associated with increased state spending.ConclusionsThere was no evidence of crowding out of other state expenditure categories or a substantial impact on total state spending, even in the COVID‐19 era. Increased federal expenditures may have shielded states from substantial budgetary impacts.
Investigation on the lipid‐lowering effect and mechanism by combining turmeric with hawthorn in C57BL/6 obese mice
Authors: Li Qiang , Hao Zongwei , Xu Huajian , Wang Xueyan 
Published: May 2024

AbstractStudy on the hypolipidemic effect of turmeric combined with hawthorn on C57BL/6 obese mice and its possible mechanism.C57 mice were fed with 60% high‐fat diet for 8 weeks to establish an obesity model, and 4 mice were slaughtered to verify whether the modeling was successful. The successful mice were divided into model group (HFD), positive group (high fat feed group [HFD] + simvastatin group [SIM]), turmeric group (HFD + TUR), hawthorn group (HFD + HAW), and para‐medicine group (HFD + para‐drug group [DOU]) for 4 weeks by gavage intervention.Different intervention groups had certain lipid‐lowering effects, and the para‐medicine group showed significant differences (p < 0.05, p < 0.01, p < 0.001) in reducing serum total cholesterol, triglycerides, low‐density lipoprotein cholesterol, glutamic acid transaminase (ALT), glutamic acid transaminase (AST), and increasing high‐density lipoprotein cholesterol. In the para‐medicine group, the protein expression of peroxisome proliferator‐activated receptor γ, fatty acid synthase, platelet‐reactive protein receptor 36, and CCAAT/enhancer binding protein α were significantly downregulated, and the protein expression of carnitine palmitoyl transferase1 and peroxisome proliferator‐activated receptor α protein expression (p < 0.01, p < 0.001), thus suggesting that turmeric and hawthorn are superior to turmeric and hawthorn alone in enhancing lipid metabolism‐related mechanisms. Combined effects of turmeric and hawthorn improve lipid metabolism in mice, protect the liver, and improve the protein expression of liver‐related genes. This study can lay the theoretical basis for the future association of medicinal food products and the development of related weight loss products.
Recurrence in lobular carcinoma of the breast: A 14‐year review
Authors: Burns Nathan , Bourke Anita 
Published: May 2024

AbstractIntroductionThe two most common types of breast cancer are invasive or infiltrating ductal carcinoma (IDC) and invasive or infiltrating lobular carcinoma (ILC) (Pestalozzi et al., J. Clin. Oncol., 26, 2008, 3006). Between 5% and 15% of invasive breast carcinomas are lobular carcinomas (Pestalozzi et al., J. Clin. Oncol., 26, 2008, 3006; Dossus and Benusiglio, Breast Cancer Res., 17, 2015, 37; Braunstein et al., Breast Cancer Res. Treat., 149, 2015, 555). The paucity of data relating to recurrence rates of lobular cancers prompted this study.MethodsA retrospective cohort study of all cases of lobular breast carcinoma reported to the Western Australia Cancer Registry with the clinical and pathological details between 2000 and 2014.ResultsOverall, 2463 subjects with a total of 2526 events of invasive lobular carcinoma of the breast. 11/2463 (0.45%) subjects met criteria for local recurrence of invasive lobular breast cancer, with an incidence of 1 in 224.ConclusionThere are clinical implications for the management and follow‐up for patients with a diagnosis of lobular cancer of the breast. Due to the low recurrence rate, now, the standard practice in our institution does not offer magnetic resonance imaging (MRI) as part of the follow‐up for ILC patients. Other centres should establish local recurrence rates to aid development of appropriate management protocols.