bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of Debye temperature and temperature-dependent EXAFS cumulants of Zn, Zr, α-Ti, Ru and Hf metals
Authors: Hieu Ho Khac , Lam Le Thu , Tam Nguyen Trong , Hong Nguyen Thi 
Published: June 2024

Abstract
In this work, the anharmonic Einstein model is developed to determine the Debye temperature and investigate the temperature effects on the extended x-ray absorption fine structure (EXAFS) cumulants of hexagonal close-packed (hcp) metals. We have derived the analytical expressions of the anharmonic effective potential, the effective force constant, the Debye temperature and the first four EXAFS cumulants as a function of axial ratio e = c/a. Numerical calculations have been conducted for hcp Zn, Zr, α-Ti, Ru and Hf metals up to temperature 800 K. Our findings indicate that the anharmonicity of thermal lattice vibrations significantly influences the EXAFS cumulants, particularly at high temperatures. Ru atoms have the strongest coupling force causing a phenomenon that Ru lattice shows a smaller thermal disorder, and Zn has a greater thermal disorder. Additionally, we highlight the significant contributions of thermal disorder to the mean-square relative displacement at high temperatures due to thermal lattice vibrations. Moreover, our Debye temperatures derived from the developed model align reasonably well with those reported in previous studies.
Direct implementation of a frequency-programmable Josephson voltage standard to provide an SI traceable optical power scale
Authors: White M G , Rufenacht A , Fox A , Gamouras A , Tomlin N A , Lehman J H , Benz S 
Published: June 2024

AbstractWe have developed a technique to determine the electrical substitution power of a cryogenic optical radiant power detector, that directly implements a frequency-programmable Josephson voltage standard (FPJVS), thus reducing the traceability chain. The optical power detector and the Josephson voltage reference are combined inside a common cryogenic environment. We demonstrate the practicality of the technique by using a FPJVS to apply a known voltage across the resistive heater of a standard NIST cryogenic planar radiometric detector. The power applied to the detector heater is calculated from a measurement of the heater resistance and the known applied voltage. The FPJVS dc bias current source supplies dc current to the resistive heater. In this demonstration, the standard uncertainty of the substituted electrical power is limited by the uncertainty of the electrical heater four-wire resistance measurement at 4 K. The uncertainty due to the resistance measurement is 1 part in 105out of a total uncertainty of 1 part in 104(k= 2) on the 1 mW optical power measurement. We aim to develop the technique, to provide traceability to the International System of Units for the picowatt power measurement of single-photon emitters such as quantum dot sources.
Feynman–Kac equation for Brownian non-Gaussian polymer diffusion
Authors: Zhou Tian , Wang Heng , Deng Weihua 
Published: June 2024

Abstract
The motion of the polymer center of mass (CM) is driven by two stochastic terms that are Gaussian white noise generated by standard thermal stirring and chain polymerization processes, respectively. It can be described by the Langevin equation and is Brownian non-Gaussian by calculating the kurtosis. We derive the forward Fokker–Planck equation governing the joint distribution of the motion of CM and the chain polymerization process. The backward Fokker–Planck equation governing only the probability density function (PDF) of CM position for a given number of monomers is also derived. We derive the forward and backward Feynman–Kac equations for the functional distribution of the motion of the CM, respectively, and present some of their applications, which are validated by a deep learning method based on backward stochastic differential equations (BSDEs), i.e. the deep BSDE method.
Synthesis, characterization, and OFET characteristics of p-type organic semiconductors incorporating diketopyrrolopyrrole and thiadiazole-quinoxaline acceptors
Authors: Takahashi Naohiro , Nishiyama Tomoki , Weng Weichun , Miwa Yuki , Marumoto Shinsuke , Kitoh-Nishioka Hirotaka , Tanaka Senku , Okubo Takashi 
Published: June 2024

Abstract
P-type Organic Semiconductors, TQx5-BT-DPP8 (1a) and TQx5-BT-DPP20 (1b), consisting of a donor unit of bithiophene (BT) and two acceptor units of thiadiazole quinoxaline (TQx) and diketopyrrolopyrrole (DPP), were synthesized, and their electronic states and physical properties were elucidated. These semiconductors demonstrate strong absorption extending from the visible to the near-infrared region, functioning effectively as strong donor dyes. The organic field-effect transistors (OFETs) exhibited normally on transistor characteristics, with carrier mobilities of 1.1 × 10−3 cm2/Vs for 1a and 3.3 × 10−4 cm2/Vs for 1b.
The role of temperature in vitality and survival assessments of beam-trawled and discarded European plaice (Pleuronectes platessa)
Authors: Uhlmann Sven Sebastian , Paoletti Silvia , Ampe Bart , Theodoridis Konstantinos , Kochzius Marc , Koeck Barbara 
Published: June 2024

Abstract
Thermal stress can influence the recovery of fish released after capture. Vitality assessments using reflex and behavioural responses require that responses can be observed reliably, independent of temperature. Here, we tested whether reflex and behavioural impairment and survival of beam-trawled and discarded European plaice (Pleuronectes platessa) are independent from seasonal air and water temperature deviations. In total, 324 beam-trawled plaice (n = 196 in summer and n = 128 in winter) were exposed to two air temperature treatments and two water treatments (i.e. modified and ambient temperatures for both). The modified treatments (i.e. cooled in summer, warmed in winter) represent the thermal shock a fish may experience when being returned to the water. All reflexes and tested behaviours were affected by ambient temperature, with high impairment noted in summer. None of the reflexes were affected by temperature shocks alone, only body flex was. Body flex was highly impaired under every exposure combination. Fish size and duration of air exposure further influenced impairment of reflexes such as head complex and tail grab. More generally, post-release survival was assessed as 21% [95% CI: 16–28%] in summer and 99% [97–100%] in winter. Beam trawling in summer is likely to induce high reflex impairment and mortality in discarded plaice, and therefore spatial–temporal mitigation approaches should be prioritized over control of on-board temperatures.
Demand for Commitment in Credit and Saving Contracts: A Field Experiment
Authors: Afzal Uzma , d’Adda Giovanna , Fafchamps Marcel , Quinn Simon , Said Farah 
Published: June 2024

Abstract
We conduct a field experiment in which we offer credit and saving contracts to the same pool of Pakistani microfinance clients. Additional treatments test ex ante demand for soft commitment (in the form of reminders, either to respondents or to their families), hard commitment (in the form of a penalty for missing an instalment) and flexibility (an option to postpone an instalment) to save or pay loan instalments on time. We find substantial demand for fixed repayment contracts in both the credit and savings domains, in ways that imply that respondents value the commitment required. While we find little or no average demand for additional contractual features, we nonetheless observe that different combinations of contractual add-ons are preferred depending on the respondent’s level of financial discipline. Respondents with high financial discipline prefer flexibility in credit contracts when combined with reminders to self while those with low discipline value penalties in savings contracts only when paired with reminders. Our results imply that, for the average microfinance client, demand for commitment is met through the regular payment schedule built into standard microcredit or commitment savings contracts. However, combining penalties or flexibility with reminders may appeal to certain subsets of clients.
Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis
Authors: Dinu Monica , Sofi Francesco , Lotti Sofia , Colombini Barbara , Mattioli Anna Vittoria , Catapano Alberico L , Casula Manuela , Baragetti Andrea , Wong Nathan D , Steg Philippe Gabriel , Ambrosio Giuseppe 
Published: June 2024

Abstract

Aims
Benefits of pharmacologic omega-3 fatty acid administration in cardiovascular prevention are controversial. Particularly, effects on coronary revascularization are unclear; also debated are specific benefits of eicosapentaenoic acid (EPA). We investigated incident coronary revascularizations, myocardial infarction (MI), stroke, heart failure (HF), unstable angina, and cardiovascular death, in subjects randomized to receive EPA or EPA + docosahexaenoic acid (EPA + DHA) vs. control.

Methods and results
Meta-analysis of randomized controlled trials (RCTs) was conducted after MEDLINE, Embase, Scopus, Web of Science, and Cochrane Library search. Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines were followed for abstracting data and assessing data quality and validity. Data were pooled using a random effects model. Eighteen RCTs with 134 144 participants (primary and secondary cardiovascular prevention) receiving DHA + EPA (n = 52 498), EPA alone (n = 14 640), or control/placebo (n = 67 006) were included. Follow-up ranged from 4.5 months to 7.4 years. Overall, compared with controls, omega-3 supplementation reduced the risk of revascularization [0.90, 95% confidence interval (CI) 0.84–0.98; P = 0.001; P-heterogeneity = 0.0002; I2 = 68%], MI (0.89, 95% CI 0.81–0.98; P = 0.02; P-heterogeneity = 0.06; I2 = 41%), and cardiovascular death (0.92, 95% CI 0.85–0.99; P = 0.02; P-heterogeneity = 0.13; I2 = 33%). Lower risk was still observed in trials where most participants (≥60%) were on statin therapy. Compared with DHA + EPA, EPA alone showed a further significant risk reduction of revascularizations (0.76, 95% CI 0.65–0.88; P = 0.0002; P-interaction = 0.005) and all outcomes except HF.

Conclusion
Omega-3 fatty acid supplementation reduced the risk of cardiovascular events and coronary revascularization, regardless of background statin use. Eicosapentaenoic acid alone produced greater benefits. The role of specific omega-3 molecules in primary vs. secondary prevention and the potential benefits of reduced revascularizations on overall health status and cost savings warrant further research.
Contributing to an inclusive education for neurodivergent students: sharing reflections, practices, and experiences
Authors: Pigato Giorgia 
Published: June 2024

Abstract
It is estimated that one in seven individuals, more than 15% of the population in the UK, are neurodivergent. In recent years, there has been a notable increase in university students disclosing disabilities, specific learning difficulties, or mental health conditions. Despite this, students with disabilities and learning differences often experience lower levels of well-being compared to their peers, and their completion rates are significantly lower. Two years ago, I was tasked with creating a training program for academic staff to enhance their support for neurodivergent students. In this commentary, I share reflections on what I have learned while developing this training, and I outline effective strategies and approaches that can be implemented in the design and delivery of educational content. I advocate a collaborative approach to training development with neurodivergent students and with colleagues with various roles. The commentary draws upon the Universal Design for Learning framework to advocate for an educational environment that is welcoming and accommodating to all learners. It champions strength-based practices, steering clear of the traditional deficit-focused narratives. My goal with this reflection is to prompt educators to reflect on their teaching methodologies, engage in conversations with their students, and to consider substantial pedagogical changes that prioritize inclusivity over reasonable adjustments.
Prioritizing commercial thinning: quantification of growth and competition with high-density drone laser scanning
Authors: Irwin Liam A K , Coops Nicholas C , Riofrío José , Grubinger Samuel G , Barbeito Ignacio , Achim Alexis , Roeser Dominik 
Published: June 2024

Abstract
Laser scanning sensors mounted on drones enable on-demand quantification of forest structure through the collection of high-density point clouds (500+ points m−2). These point clouds facilitate the detection of individual trees enabling the quantification of growth-related variables within a stand that can inform precision management. We present a methodology to link incremental growth data obtained from tree cores with crown models derived from drone laser scanning, quantifying the relative growth condition of individual trees and their neighbours. We stem-mapped 815 trees across five stands in north-central British Columbia, Canada of which 16% were cored to quantify recent basal area growth. Point clouds from drone laser scanning and orthomosaic imagery were used to locate trees, model three-dimensional crown features, and derive competition metrics describing the relative distribution of crown sizes. Local access to water and light were simulated using topographic wetness and potential solar irradiance indices derived from high-resolution terrain and surface models. Wall-to-wall predictions of recent basal area growth were produced from the best-performing model and summarized across a grid alongside a tree-level competition index. Overall, crown volume was most strongly correlated with observed differences in 5-year basal area increment (R2 = 0.70, P &lt; .001). Competition and solar irradiance metrics were significant as univariate predictors (P &lt; .001) but nonsignificant when included in multivariate models with crown volume. Using predictions from the best-performing model and laser-scanning-derived competition metrics, we present a newly developed growth competition index to assess variability and inform commercial thinning prescription prioritization. Growth predictions, competition metrics, and the growth competition index are summarized into maps that could be used in an operational workflow. Our methodology presents a new capacity to capture and quantify intra-stand variation in growth by combining competition metrics and measures of recent growth with high-density drone laser scanning data.
Use of simulation to optimize a sweet corn breeding program: implementing genomic selection and doubled haploid technology
Authors: Peixoto Marco Antônio , Coelho Igor Ferreira , Leach Kristen A , Lübberstedt Thomas , Bhering Leonardo Lopes , Resende Márcio F R 
Published: June 2024

Abstract
Genomic selection and doubled haploids hold significant potential to enhance genetic gains and shorten breeding cycles across various crops. Here, we utilized stochastic simulations to investigate the best strategies for optimize a sweet corn breeding program. We assessed the effects of incorporating varying proportions of old and new parents into the crossing block (3:1, 1:1, 1:3, and 0:1 ratio, representing different degrees of parental substitution), as well as the implementation of genomic selection in two distinct pipelines: one calibrated using the phenotypes of testcross parents (GSTC scenario) and another using F1 individuals (GSF1). Additionally, we examined scenarios with doubled haploids, both with (DH) and without (DHGS) genomic selection. Across 20 years of simulated breeding, we evaluated scenarios considering traits with varying heritabilities, the presence or absence of genotype-by-environment effects, and two program sizes (50 vs 200 crosses per generation). We also assessed parameters such as parental genetic mean, average genetic variance, hybrid mean, and implementation costs for each scenario. Results indicated that within a conventional selection program, a 1:3 parental substitution ratio (replacing 75% of parents each generation with new lines) yielded the highest performance. Furthermore, the GSTC model outperformed the GSF1 model in enhancing genetic gain. The DHGS model emerged as the most effective, reducing cycle time from 5 to 4 years and enhancing hybrid gains despite increased costs. In conclusion, our findings strongly advocate for the integration of genomic selection and doubled haploids into sweet corn breeding programs, offering accelerated genetic gains and efficiency improvements.
A novel diterpenic derivative produced by Streptomyces chrestomyceticus ADP4 is a potent inhibitor of biofilm and virulence factors in Candida albicans and C. auris
Authors: Singh Radha , Shukla Jyoti , Ali Mohd , Dubey Ashok K 
Published: June 2024

Abstract

Aim
Isolation, identification, structural and functional characterization of potent anti-Candida compound with specific antagonistic activities against significant human pathogens, Candida albicans and C. auris.

Methods and Results
The compound (55B3) was purified from the metabolites produced by Streptomyces chrestomyceticus ADP4 by employing column chromatography. The structure of 55B3 was determined from the analyses of spectral data that included LCMS, nuclear magnetic resonance, FTIR, and UV spectroscopies. It was identified as a novel derivative of diterpenic aromatic acid, 3-(dictyotin-11′-oate-15′α, 19′β-olide)-4-(dictyotin-11′-oate-15″α, 19″β-olide)-protocatechoic acid. The compound displayed potent antifungal and anti-biofilm activities against C. albicans ATCC 10231 (Minimum Inhibitory Concentration, MIC90:14.94 ± 0.17 μgmL−1 and MBIC90: 16.03 ± 1.1 μgmL−1) and against C. auris CBS 12372 (MIC90: 21.75 ± 1.5 μgmL−1 and Minimum Biofilm Inhibitory Concentration, MBIC90: 18.38 ± 1.78 μgmL−1). Further, pronounced inhibition of important virulence attributes of Candida spp., e.g. yeast-to-hyphae transition, secretory aspartyl proteinase and phospholipase B by 55B3 was noted at subinhibitory concentrations. A plausible mechanism of anti-Candida action of the compound appeared to be the inhibition of ergosterol biosynthesis, which was inhibited by 64 ± 3% at the MIC90 value. The non-cytotoxic attribute of the compound was noted in the liver cell line (HepG2 cells).

Conclusion
The present work led to the discovery of a novel diterpenic derivative produced by S. chrestomyceticus ADP4. The compound displayed potent anti-Candida activity, particularly against the two most significant human pathogens, C. albicans and C. auris, which underlined its significance as a potential drug candidate for infections involving these pathogens.
Taxonomy of the two nominal species of the deep-sea clawed lobsters Nephropsis serrata Macpherson, 1993 and N. hamadai Watabe & Ikeda, 1994 (Decapoda: Astacidea: Nephropidae)
Authors: Chan Tin-Yam , Wakabayashi Kaori , Chen Chien-Lin , Kato Mikio , Chang Su-Ching 
Published: June 2024

Abstract
The deep-sea clawed lobster Nephropsis hamadai Watabe & Ikeda, 1994, described from Japan, has been suspected to be a synonym of Nephropsis serrata Macpherson, 1993, recorded from Australia (type locality) to Taiwan. The availability of recently collected material from Japan referred to N. hamadai allowed detailed morphological and molecular comparisons of topotypic specimens of N. serrata and N. hamadai. Re-examination of the holotype of N. serrata revealed that the major difference proposed for separating N. hamadai from N. serrata was based on an error in the original description of the latter species. As there are very low genetic divergences and no morphological differences between the Australian and Japanese materials referable to N. serrata and N. hamadai, these two names are now confirmed to be synonyms.
Brain-immune interactions: implication for cognitive impairments in Alzheimer's disease and autoimmune disorders
Authors: Kadam Rashmi , Gupta Muskan , Lazarov Orly , Prabhakar Bellur S 
Published: June 2024

Abstract
Progressive memory loss and cognitive dysfunction, encompassing deficits in learning, memory, problem solving, spatial reasoning, and verbal expression, are characteristics of Alzheimer's disease and related dementia. A wealth of studies has described multiple roles of the immune system in the development or exacerbation of dementia. Individuals with autoimmune disorders can also develop cognitive dysfunction, a phenomenon termed “autoimmune dementia.” Together, these findings underscore the pivotal role of the neuroimmune axis in both Alzheimer's disease and related dementia and autoimmune dementia. The dynamic interplay between adaptive and innate immunity, both in and outside the brain, significantly affects the etiology and progression of these conditions. Multidisciplinary research shows that cognitive dysfunction arises from a bidirectional relationship between the nervous and immune systems, though the specific mechanisms that drive cognitive impairments are not fully understood. Intriguingly, this reciprocal regulation occurs at multiple levels, where neuronal signals can modulate immune responses, and immune system–related processes can influence neuronal viability and function. In this review, we consider the implications of autoimmune responses in various autoimmune disorders and Alzheimer's disease and explore their effects on brain function. We also discuss the diverse cellular and molecular crosstalk between the brain and the immune system, as they may shed light on potential triggers of peripheral inflammation, their effect on the integrity of the blood-brain barrier, and brain function. Additionally, we assess challenges and possibilities associated with developing immune-based therapies for the treatment of cognitive decline.
Numerical study of motorbike aerodynamic wing kit
Authors: Chien Han , Wang Chin-Cheng 
Published: June 2024

Abstract
This study aims to design the configuration of an aerodynamic wing kit (AWK) on a racing motorbike to achieve the highest downforce-to-drag ratio. The numerical study involves a motorbike traveling in a straight line, where the AWK improves performance and safety by generating downforce to prevent lift. The geometry of the AWK uses a NACA 4412 airfoil with a span of 0.6 m. The computational mesh is generated using SnappyHexMesh and installed on a simplified motorbike to minimize the mesh skewness. The Navier–Stokes equations are solved with OpenFOAM computational fluid dynamics using the Reynolds-averaged Navier–Stokes k-ω SST and large eddy simulation (LES) turbulence models. Case 1 compares a motorbike with and without a dummy, both equipped with the AWK, varying the angle of attack (AoA) from 0 to −41°. Case 2 studies the single wing at different wind speeds (i.e. 20, 60 and 100 m/s) to determine the highest downforce-to-drag ratio at an AoA of −37°. These results serve as the basis for Case 3, which investigates non-parallel wing configurations with a fixed upper wing and a rotating lower wing. In Case 4, where both upper and lower wings rotate simultaneously as parallel wings, the peak downforce-to-drag ratio occurs at an AoA of −41°. Finally, Case 5 modifies the AoA of −41° of the parallel wing of Case 4 to a closed-wing version to comply with Fédération Internationale de Motocyclisme safety regulations. With the LES turbulence model, unsteady and complex turbulence structures can be visualized using the Q-criterion. A comparison of the time-averaged lift coefficient between the wingless and closed-wing configurations shows an increase in downforce of approximately 360%. Subsequently, the popularity of AWK will contribute to the safety of racing motorbike driving.