bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corrosion of M5 in PWRs: Quantification of Li, B, H and Nb in the Oxide Layers Formed Under Different Conditions
Authors: Bossis Philippe , Raepsaet Caroline , Tupin Marc , Bisor-Melloul Caroline , Khodja Hicham , Blat Martine , Ambard Antoine , Miquet Alain , Kaczorowski Damien 
Published: October 2011

Abstract
Until now, most of the detailed characterizations of the M5 corrosion behaviour were performed under standard PWR operating conditions, under moderate Li content and moderate temperature of the primary coolant. In this study, in addition to these standard conditions, two demanding operating conditions were explored: increased Li chemistry and elevated temperature. The objective is to establish whether these more demanding conditions have an impact on the structure of the oxide layers formed, on Nb, Li and B contents in these layers and on Hydrogen pickup of the cladding. The structure of oxide layers was studied by microscopy, the Nb content and distribution by Electron Probe Micro Analysis, the Li and B contents and distributions by Nuclear Reaction Analysis and the hydrogen pickup by gas extraction. It was observed that the stability of the corrosion behaviour of M5 is not affected by increased Li or elevated temperature conditions. The hydrogen pickup fraction of M5 is not modified by increased Li conditions or by irradiation temperature with measured contents (&lt;100 ppm) below the solubility limit at irradiation temperature (586–631 K range). Moreover, no significant release of Nb from the oxide in the primary coolant was observed, whatever the operating conditions can be, with quantification accuracy below 0.05%. The respective Li and B contents reached in oxides are of the same order of magnitude under the all three conditions, with average Li content around 15 ppm and average B content varying from 70 to 140 ppm, corresponding to a range where enhanced corrosion is neither observed, nor expected.
Formation of a miscibility gap in laser-crystallized poly-SiGe thin films
Authors: Weizman M. , Nickeal N. H. , Sieber I. , Yan B. 
Published: October 2011

AbstractLaser-crystallized polycrystalline silicon-germanium (poly-SiGe) thin films on glass substrates were characterized with energy dispersive X-ray and Raman spectroscopy. In the course of the crystallization strong lateral segregation occurs for laser-crystallized poly-Si1-xGex with 0.33 < x < 0.7, causing the local Ge content to differ by as much as 40 % from the average value. The segregation manifests itself in the appearance of well-resolved peaks in the Raman phonon modes. This mode splitting in the Raman spectra is interpreted as the formation of well defined alloy phases with a miscibility gap in between.
Argos, le fameux chien de l'Odyssée, qui attendait son maître
Authors: Costantini Michel 
Published: October 2011

Résumé Le long sillon tracé par Jean-Claude Coquet pour labourer le champ d’une sémiotique phénoménologique (qu’elle soit nommée « subjectale », « du continu », « continuiste », ou encore « des instances ») ne pouvait qu’être... sensible au sensible. À travers plusieurs interventions des dernières années (de l’ouvrage de 2007 sur le jeu de phusis et de logos jusqu’à une communication vénitienne de 2010), on cherche à discerner quelques vertus d’une telle approche : ce qu’elle permet d’entrevoir pour traiter la question de l’empêtrement, ce qu’elle autorise à penser de la problématique du kairos , et, dans le prolongement, ce qu’elle appelle à approfondir pour lire certain tableau de plate peinture.
Le concept de travail et la théorie sociale critique
Authors: Noguera José Antonio 
Published: October 2011

Résumé Les débats actuels autour du concept de travail n’énoncent pas toujours clairement certains des points essentiels qui le caractérisent dans la tradition de la théorie sociale critique initiée par Marx. Celle-ci a souvent mis en évidence les relations entre le travail et l’émancipation. L’article propose trois axes conceptuels complémentaires à l’axe traditionnel « valorisation versus dépréciation » du travail : concept étendu de travail versus concept réduit, productivisme versus antiproductivisme, et centralité normative versus non-centralité du travail. À partir de ces éléments, l’article procède à la critique de certains lieux communs sur le concept de travail chez Marx, et énumère les différents chemins conceptuels empruntés par les traditions marxistes postérieures. L’objectif de ce texte est ainsi de proposer une analyse critique du concept de travail chez Habermas.
MicroRNAs Regulate Dendritic Cell Differentiation and Function
Authors: Turner Marian L. , Schnorfeil Frauke M. , Brocker Thomas 
Published: October 2011

Abstract
MicroRNAs (miRNAs) are an important class of cellular regulators that modulate gene expression and thereby influence cell fate and function. In the immune system, miRNAs act at checkpoints during hematopoietic development and cell subset differentiation, they modulate effector cell function, and they are implicated in the maintenance of homeostasis. Dendritic cells (DCs), the professional APCs involved in the coordination of adaptive immune responses, are also regulated by miRNAs. Some DC-relevant miRNAs, including miR-155 and miR-146a, are shared with other immune cells, whereas others have been newly identified. In this review, we summarize the current understanding of where miRNAs are active during DC development from myeloid precursors and differentiation into specialized subsets, and which miRNAs play roles in DC function.
Similarities and differences in peripheral blood gene‐expression signatures of individuals with schizophrenia and their first‐degree biological relatives
Authors: Glatt Stephen J. , Stone William S. , Nossova Nadine , Liew Choong‐Chin , Seidman Larry J. , Tsuang Ming T. 
Published: October 2011

AbstractSeveral studies have evaluated the potential utility of blood‐based whole‐transcriptome signatures as a source of biomarkers for schizophrenia. This endeavor has been complicated by the fact that individuals with schizophrenia typically differ from appropriate comparison subjects on more than just the presence of the disorder; for example, individuals with schizophrenia typically receive antipsychotic medications, and have been dealing with the sequelae of this chronic illness for years. The inability to control such factors introduces a considerable degree of uncertainty in the results to date. To overcome this, we performed a blood‐based gene‐expression profiling study of schizophrenia patients (n = 9) as well as their unmedicated, nonpsychotic, biological siblings (n = 9) and unaffected comparison subjects (n = 12). The unaffected biological siblings, who may harbor some of the genetic predisposition to schizophrenia, exhibited a host of gene‐expression differences from unaffected comparison subjects, many of which were shared by their schizophrenic siblings, perhaps indicative of underlying risk factors for the disorder. Several genes that were dysregulated in both individuals with schizophrenia and their siblings related to nucleosome and histone structure and function, suggesting a potential epigenetic mechanism underlying the risk state for the disorder. Nonpsychotic siblings also displayed some differences from comparison subjects that were not found in their affected siblings, suggesting that the dysregulation of some genes in peripheral blood may be indicative of underlying protective factors. This study, while exploratory, illustrated the potential utility and increased informativeness of including unaffected first‐degree relatives in research in pursuit of peripheral biomarkers for schizophrenia. © 2011 Wiley Periodicals, Inc.
Primary Study of Lymph Node Metastasis‐Related Serum Biomarkers in Breast Cancer
Authors: Wang Liang , Su Dan , Yan Huai‐Jun , Xu Jian‐Hua , Zheng Zhi‐Guo , Hu Yan‐Jun , Pan Xiao‐Dan , Ding Xiao‐Wen , Chen Chun , Chen Bin , Mao Wei‐Min , Meng Xu‐Li 
Published: October 2011

AbstractThe aim of this study was to detect the pretreatment serum protein profiles of breast cancer patients by mass spectrometry (MS) to screen candidate tumor biomarkers, which will supply a simple, accurate, and minimally invasive method to predict the axillary lymph node metastasis of breast cancer. We used magnetic bead‐based weak cation‐exchange chromatography followed by matrix‐assisted laser desorption and ionization time‐of‐flight MS to detect proteins in the sera of 54 cases of axillary node‐negative breast cancer, 47 cases of axillary node‐positive breast cancer, and 101 healthy controls. The protein profiles were analyzed to screen tumor biomarkers and lymph node metastasis‐associated proteins to establish and verify a diagnostic model. Comparison of the protein profiles between the two cancer groups resulted in a total of 111 discriminate m/z peaks that were associated with breast cancer. Furthermore, 40 discriminate m/z peaks were detected between breast cancer patients with and without axillary node metastases. Four protein m/z peaks at 5,643, 4,651, 2,377, and 2,240 were used to construct a diagnosis model, and cross‐validation indicated that breast cancer with and without axillary node metastasis was identified with 87.04% sensitivity (47/54), 87.23% specificity (41/47), and 87.13% accuracy (88/101). These proteins could potentially be used as predictive biomarkers to distinguish between breast cancer patients with or without lymph node metastasis. Anat Rec, , 2011. © 2011 Wiley‐Liss, Inc.
Ganglion Cell Distribution and Retinal Resolution in the Florida Manatee, Trichechus Manatus Latirostris
Authors: Mass Alla M. , Ketten Darlene R. , Odell Daniel K. , Supin Alexander Ya. 
Published: October 2011

AbstractThe topographic organization of retinal ganglion cells was examined in the Florida manatee (Trichechus manatus latirostris) to assess ganglion cell size and distribution and to estimate retinal resolution. The ganglion cell layer of the manatee's retina was comprised primarily of large neurons with broad intercellular spaces. Cell sizes varied from 10 to 60 μm in diameter (mean 24.3 μm). The retinal wholemounts from adult animals measured 446–501 mm2 in area with total ganglion cell counts of 62,000–81,800 (mean 70,200). The cell density changed across the retina, with the maximum in the area below the optic disc and decreasing toward the retinal edges and in the immediate vicinity of the optic disc. The maximum cell density ranged from 235 to 337 cells per millimeter square in the adult retinae. Two wholemounts obtained from juvenile animals were 271 and 282 mm2 in area with total cell numbers of 70,900 and 68,700, respectively (mean 69,800), that is, nearly equivalent to those of adults, but juvenile retinae consequently had maximum cell densities that were higher than those of adults: 478 and 491 cells per millimeter square. Calculations indicate a retinal resolution of ∼19′ (1.6 cycles per degree) in both adult and juvenile retinae. Anat Rec, 2012. © 2011 Wiley Periodicals, Inc.
The Gallbladder ofUranoscopus ScaberL. (Teleost Perciform Fish) is Lined by Specialized Cholecystocytes
Authors: Gilloteaux J. , Ott Donald W. , Oldham‐Ott Carla K. 
Published: October 2011

AbstractThe gallbladder ofUranoscopus exhibits a mucosal surface layer of simple columnar epithelium composed of specialized cholecystocytes. The apices show storage and mucous secretions, typical microvilli, and very apical projections extending deep into the luminal contents. Many organelles and heterogeneous vesicles of diverse size fill the cytoplasm, including neutral mucins, mitochondria, peroxisomes, lysosomal bodies, and lipid‐rich deposits with cholesterol inclusions. The fibromuscular layer shows little blood supply and contains scattered lymph‐like walls with minute cholesterol inclusions. The remaining muscular, subserosal, and serosal or adventitial layers of this species do not show any histologic differences to those of other Vertebrates. It was unexpected to find cholesterol inclusions in the fatty deposits of the cholecystocytes, similar to those noted in human cholesterolosis and in some forms of hypercholesterolemia, in this teleostean. In addition, aggregations of mitochondria and anomalous mitochondrial morphologies were found that resemble oncocytoma‐like changes. Anat Rec, 2011. © 2011 Wiley‐Liss, Inc.
Arterial Head Vascularization Cartographies of Normal Metencephalic Dogs Using Magnetic Resonance Angiography
Authors: Jacqmot Olivier D. , Snaps Frederic R. , Maquet Nathalie M. , Heinen Marie Pierre A. , Gabriel Annick E. 
Published: October 2011

AbstractThe aim of our study was to establish head arterial cartographies—useful for the diagnosis of brain diseases leading to cerebral vascular modifications—by means of magnetic resonance angiography (MRA). Casts of the arterial vascular brain system were used to corroborate the MRA results as they can be easily rotated in nonvirtual three‐dimensions and give an accurate view of the arteries calibre and origin. Two types of 3T MRA images were used: three‐dimensional fast low‐angle shot (3D‐FLASH) acquisition sequenced every 20 s, paired with injection of a paramagnetic contrast medium, and three‐dimensional time‐of‐flight (3D‐TOF) acquisition sequenced every 300 s. 3D‐FLASH acquisition gives very accurate images of the cerebral arteries and veins, but must be used with care in debilitated animals. 3D‐TOF acquisition is less accurate and gives only images of the main cerebral arteries without showing the venous system. It is, however, a viable diagnostic method for monitoring vascular lesions (e.g., cerebral hemorrhages). Anat Rec, 2011. © 2011 Wiley‐Liss, Inc.
Embryonic Staging Table for a Direct‐Developing Salamander, Plethodon cinereus (Plethodontidae)
Authors: Kerney Ryan 
Published: October 2011

AbstractThis work presents a refined staging table for the direct‐developing red‐backed salamander Plethodon cinereus, which is based on the incomplete staging system of James Norman Dent (J Morphol 1942; 71:577–601). This common species from eastern North America is a member of the species‐rich lungless salamander family Plethodontidae. The staging table presented here covers several stages omitted by Dent and reveals novel developmental features of P. cinereus embryos. These include putative Leydig cells and open gill clefts, which are found in larvae of metamorphosing species but were previously reported as absent in direct‐developing Plethodon. Other features found in larvae of metamorphosing salamander species, such as the palatopterygoid bone and lateral line neuromasts, were not observed in this material. The occurrence of larval and metamorphic features in these embryos has direct bearing on the patterns of life history evolution within the plethodontidae family. This study emphasizes the degree to which typically larval structures are retained in this direct‐developing species and provides a staging table for further investigations into the development and evolution of plethodontid salamanders. Anat Rec, 2011. © 2011 Wiley‐Liss, Inc.
Immunohistochemical Analysis of the Proteolytic Enzyme Subtilase in the Digestive Organs of the Sea Urchin Strongylocentrotus intermedius
Authors: Ura Kazuhiro , Hasegawa Syuto , Tanaka Eri , Gotoh Takahiro , Ojima Takao , Takagi Yasuaki 
Published: October 2011

AbstractSubtilase, a major protease in the short‐spined sea urchin (Strongylocentrotus intermedius), was isolated and used as antigen for the subsequent production of a specific polyclonal antibody. Immunoreactive cells were observed by immunohistochemical analysis in granules in the anterior and posterior stomach and the anterior intestine. These granules, which were most numerous in the anterior stomach, also stained intensely with methylene blue‐Azure II. However, granules in cells of the esophagus, posterior intestine, and rectum were not stained by this antibody. We conclude that subtilase mainly localizes in the stomach and anterior intestine of the sea urchin. Anat Rec, 2012. © 2011 Wiley Periodicals, Inc.
Unique hue data for colour appearance models. Part II: Chromatic adaptation transform
Authors: Xiao Kaida , Fu Chenyang , Mylonas Dimitris , Karatzas Dimosthenis , Wuerger Sophie 
Published: October 2011

AbstractUnique hue settings of 185 observers under three room‐lighting conditions were used to evaluate the accuracy of full and mixed chromatic adaptation transform models of CIECAM02 in terms of unique hue reproduction. Perceptual hue shifts in CIECAM02 were evaluated for both models with no clear difference using the current Commission Internationale de l'Éclairage (CIE) recommendation for mixed chromatic adaptation ratio. Using our large dataset of unique hue data as a benchmark, an optimised parameter is proposed for chromatic adaptation under mixed illumination conditions that produces more accurate results in unique hue reproduction. © 2011 Wiley Periodicals, Inc. Col Res Appl, 2013
Evaluation of the performance of a tandem mass spectral library with mass spectral data extracted from literature
Authors: Würtinger Philipp , Oberacher Herbert 
Published: October 2011

MSforID represents a database of tandem mass spectral data obtained from (quasi‐)molecular ions produced by atmospheric pressure ionization methods. At the current stage of development the library contains 12 122 spectra of 1208 small (bio‐)organic molecules.The present work was aimed to evaluate the performance of the MSforID library in terms of accuracy and transferability with a collection of fragment ion mass spectra from various compounds acquired on multiple instruments. A literature survey was conducted to collect the set of sample spectra. A total number of 554 spectra covering 291 compounds were extracted from 109 publications. The majority of spectra originated from publications on applications of LC/MS/MS in drug monitoring, pharmacokinetics, environmental analysis, forensic analysis as well as food analysis. Almost all types of tandem mass spectrometric instruments distributed by the five most important instrument vendors were included in the study.The overall sensitivity of library search was found to be 96.4%, which clearly proves that the MSforID library can successfully handle data from a huge variety of mass spectrometric instruments to allow accurate compound identification. Only for spectra containing three or more fragment ions, however, the rate of classified matches (= matches with a relative average match probability (ramp) score > 40.0) was 95%. Ambiguous or unclassified results were mainly obtained for searches with single precursor‐to‐fragment ion transitions due to the insufficient specificity of such a low amount of structural information to unequivocally define a single compound. Copyright © 2011 John Wiley & Sons, Ltd.
Fuzzy lattice based technique for classification of power quality disturbances
Authors: Kapoor Rajiv , Gupta Rashmi 
Published: October 2011

SUMMARYIn this paper, a new technique is proposed for classification of power quality disturbances. The proposed technique is based on the concept of local non‐linear relation to extract the feature specific data. To extract any change occurring in the patterns of power quality events, non‐linear Gaussian functions have been used that result in formation of fuzzy lattices. These fuzzy lattices are expressed in the form of Schrödinger equation to find the kinetic energy involved corresponding to any change occurring in the power quality disturbances. Finally, the kinetic energy parameter embedded in two dimension space has been used to distinguish various power quality events. The proposed technique efficiently distinguishes various real time power quality events in a single cycle. Copyright © 2011 John Wiley & Sons, Ltd.
Effect of crush and axotomy of phrenic nerves on oxidative stress in diaphragm muscle of rats
Authors: Sayir Fuat , Kavak PhD Servet , Meral İsmail , Demir Halit , Cengiz Nurettin , Çobanoğlu Ufuk 
Published: October 2011

AbstractIntroduction: In this study we investigated the effect of crush and axotomy of phrenic nerves on oxidative stress and antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Results: The malondialdehyde level increased in diaphragm muscles after both crush and axotomy. The antioxidant enzymes, such as superoxide dismutase, glutathione peroxidase, carbonic anhydrase, and catalase, decreased in diaphragm muscles after both crush and axotomy. Conclusions: Crushing or axotomizing the phrenic nerves may produce oxidative stress in the diaphragm muscle of the rat by increasing lipid peroxidation and decreasing antioxidant enzyme activities. Muscle Nerve, 2012
Energy-efficient post-harvest storage and handling.
Authors: East A. R. 
Published: October 2011

Abstract
Reducing energy consumption in the supply of fresh produce provides economic advantages by reducing costs, ensuring access to green-aware markets and customers and alleviating the future impact of carbon trading systems on profitability. While any process change should be fully investigated with a systems-thinking approach, such as a life cycle analysis, this work focuses on the post-harvest section of horticultural supply chains (i.e. from producer gate to retailer door). Most typical post-harvest supply chains feature operations of cooling, handling, storage and transportation. This paper provides a review of: (a) the drivers for energy efficiency, (b) energy consumption practices and means of increasing energy efficiency in contemporary supply chains and (c) current developments and ideas being suggested as possible energy use reduction strategies in future fresh produce supply chains.
Left ventricular systolic and diastolic function, remodelling, and clinical outcomes among patients with diabetes following myocardial infarction and the influence of direct renin inhibition with aliskiren
Authors: Shah Amil M. , Shin Sung Hee , Takeuchi Madoka , Skali Hicham , Desai Akshay S. , Køber Lars , Maggioni Aldo P. , Rouleau Jean L. , Kelly Roxzana Y. , Hester Allen , Keefe Deborah , McMurray John J. V. , Pfeffer Marc A. , Solomon Scott D. 
Published: October 2011

AimsWe assessed the relationship between diabetes and cardiac structure and function following myocardial infarction (MI) and whether diabetes influences the effect of direct renin inhibition on change in left ventricular (LV) size.Methods and resultsThe ASPIRE trial enrolled 820 patients 2–8 weeks after MI with ejection fraction ≤45% and randomized them to the direct renin inhibitor aliskiren (n= 423) or placebo (n = 397) added to standard medical therapy. Echocardiography was performed at baseline and after 36 weeks in 672 patients with evaluable paired studies. Compared with non‐diabetic patients, diabetic patients (n = 214) were at higher risk for a composite of cardiovascular (CV) death, heart failure hospitalization, recurrent MI, stroke, or aborted sudden death (14 vs. 7%; adjusted hazard ratio 1.63, 95% confidence interval 1.01–2.64, P= 0.045), despite similar left ventricular ejection fraction (37.9 ± 5.3 vs. 37.6 ± 5.2%, P= 0.48) and end‐systolic volume (ESV) (84 ± 25 vs. 82 ± 28 mL, P= 0.46). Diabetic patients demonstrated greater concentric remodelling (relative wall thickness 0.38 ± 0.07 vs. 0.36 ± 0.07, P= 0.0002) and evidence of higher LV filling pressure (E/E′ 11.1 ± 5.3 vs. 9.1 ± 4.3, P= 0.0011). At 36 weeks, diabetic patients experienced similar per cent reduction in ESV overall (−4.9 ± 17.9 vs. −5.5 ± 16.9, P= 0.67) but tended to experience greater reduction in ESV than non‐diabetic patients when treated with aliskiren (interaction P = 0.08).ConclusionsCompared with non‐diabetic patients, diabetic patients are at increased risk of CV events post‐MI despite no greater LV enlargement or reduction in systolic function. Diabetic patients demonstrate greater concentric remodelling and evidence of higher LV filling pressure, suggesting diastolic dysfunction as a potential mechanism for the higher risk observed among these patients.