bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sterically Hindered Oleogel‐Based Underwater Adhesive Enabled by Mesh‐Tailoring Strategy
Authors: Zhang Bin , Zhang Pengli , Zhang Guoliang , Ma Chunfeng , Zhang Guangzhao 
Published: April 2024

AbstractUnderwater adhesives hold significant relevance in daily life and numerous industrial applications. Despite considerable efforts, developing scalable, high‐performance underwater adhesives through a simple and effective method remains a formidable challenge. This study presents a novel mesh‐tailoring strategy for in situ, rapid, and ultrastrong oleogel‐based underwater adhesives (OUA), which comprises a highly crosslinked polyurethane network with a matching mesh size (≈2.22 nm) that precisely entraps bio‐based epoxidized soybean oil (ESO) molecules (≈2.31 nm) by steric hindrance effect. This oleogel exhibits unprecedented robust mechanical properties (≈35 MPa) and maintains stability under extreme conditions, including high temperatures (100 °C), high pressures (30 MPa), and immersion in various solvents (water, ethanol, or ESO). In particular, this oleogel displays high hydrophobicity, rapid curing, and strong interface affinity, resulting in ultrahigh underwater adhesion strength (up to 2.13 MPa) and exceptional substrate universality. Moreover, the remarkable environmental adaptability and stability of OUA enable its use in harsh aqueous environments, including acidic/alkaline, saline, and extreme temperature solutions. The comprehensive capabilities of the OUA underscore its potential for building underwater structures, repairing leaky containers, and sealing broken submarine pipelines. This research establishes the foundation for the designing of next‐generation underwater adhesives and offers fresh perspectives for exploring oleogel‐based materials.
Photochemical Synthesis of Chiral Heterocycles via Asymmetric Carbon‐Heteroatom Bond Formation
Authors: Brijwashi Sharma Yogesh , Saha Sanjukta , Mohan Guru Murali 
Published: April 2024

AbstractChiral heterocyclic compounds play a crucial role in the pharmaceutical science, materials science, and agrochemical industries. The critical step for synthesizing chiral heterocycles is the formation of asymmetric carbon‐heteroatom bonds, which can be achieved in a chiral environment under thermal or photochemical conditions. However, photochemical asymmetric transformation has become an area of immense growth in the past 15 years. In the drug discovery and development era, chiral photochemical transformations have drawn the attention of researchers to develop new synthetic strategies for chiral heterocycles via asymmetric carbon‐heteroatom bond formation. Chiral photochemistry in the pathway of asymmetric synthesis requires a chirality source which is transferred to the products. A catalytic chiral metal complexing agent or a chiral photosensitizer that generally follows a single electron transfer (SET) or oxidative and reductive quenching cycle has been widely exploited to achieve this goal. In this review, we have demonstrated the recent development of photochemical synthesis of chiral heterocycles via asymmetric carbon‐heteroatom bond formation by using a chiral metal catalyst, asymmetric organocatalyst, or dual catalytic system based on their plausible mechanism.
Mild and Catalyst‐Free Phosphination of Isocyanates with [TBA][P(SiCl3)2] for the Synthesis of Phosphinecarboxamides
Authors: Xu Wen‐Bo , Li Ming , Chai Yao , Tian Ya‐Ling , Wang Xi‐Cun , Quan Zheng‐Jun 
Published: April 2024

AbstractA procedure utilizing [TBA][P(SiCl3)2] as P source for the synthesis of phosphinecarboxamides is presented. The synthesis involves the reaction of [TBA][P(SiCl3)2] with isocyanates. These compounds act as highly effective reagents for the subsequent phosphination of isocyanates, leading to the formation of phosphine(triscarboxamides). This reaction proceeds swiftly under mild and straightforward conditions, making it suitable for a wide range of commercially available isocyanates.
Regiodivergent and Enantioselective Synthesis of Cyclic Sulfones via Ligand‐Controlled Nickel‐Catalyzed Hydroalkylation
Authors: Fan Chao , Dhawa Uttam , Qian Deyun , Sakic Davor , Morel Jennifer , Hu Xile 
Published: April 2024

AbstractCyclic sulfones have demonstrated important applications in drug discovery. However, the catalytic and enantioselective synthesis of chiral cyclic sulfones remains challenging. Herein, we develop nickel‐catalyzed regiodivergent and enantioselective hydroalkylation of sulfolenes to streamline the synthesis of chiral alkyl cyclic sulfones. The method has broad scope and high functional group tolerance. The regioselectivity can be controlled by ligands only. A neutral PYROX ligand favors C3‐alkylation whereas an anionic BOX ligand favors C2‐alkylation. This control is kinetic in origin as the C2‐bound Ni intermediates are always thermodynamically more stable. Reactivity study of a wide range of relevant Ni intermediates reveal a NiI/NiIII catalytic cycle with a NiII−H species as the resting state. The regio‐ and enantio‐determining step is the insertion of this NiII−H species into 2‐sulfolene. This work provides an efficient catalytic method for the synthesis of an important class of organic compounds and enhances the mechanistic understanding of Ni‐catalyzed stereoselective hydroalkylation.
Type I Photoinitiator Based on Sustainable Carbon Dots
Authors: Li Ruiping , Guo Hongda , Luo Xiongfei , Wang Qunying , Pang Yulian , Li Shujun , Liu Shouxin , Li Jian , Strehmel Bernd , Chen Zhijun 
Published: April 2024

AbstractSustainable carbon dots comprising surficial oxime ester groups following homolytic bond cleavage exhibit potential as photoinitiators for traditional free radical photopolymerization. Carbon dots were made following a solvothermal procedure from sustainable furfural available from lignocellulose. Surficial aldehyde moieties reacted with hydroxylamine to the respective oxime while reaction with benzoyl chloride resulted in a biobased Type I photoinitiator comprising sustainable carbon dot (CD‐PI). Photoinitiating ability was compared with the traditional photoinitiator (PI) ethyl (2,4,6‐trimethyl benzoyl) phenyl phosphinate (TPO‐L) by real‐time FTIR with UV exposure at 365 nm. Photopolymer composition based on a mixture of urethane dimethacrylate (UDMA) and tripropylene glycol diacrylate (TPGDA) resulted in a similar final conversion of about 70 % using either CD‐PI or TPO‐L. Nevertheless, it appeared homogeneous in the case of compositions processed with CD‐PI, while those made with TPO‐L were heterogeneous as shown by two glass transition temperatures. Moreover, the migration rate of CD‐PI in the cured samples was lower in comparison with those samples using TPO‐L as PI.
Cyano group‐containing DOPO derivative for improving the flame retardancy, smoke suppression, and mechanical properties of epoxy resins
Authors: Zhang Juan , Ma Huiru , Gao Yuan , Kang Jing , Li Ya , Chen Yuan , Liu Weipeng , Duan Huajun 
Published: April 2024

AbstractIn order to obtain an efficient flame retardant and smoke suppressor without sacrificing mechanical properties of epoxy resin (EP). A cyano group‐containing 9,10‐dihydro‐9‐oxa‐10‐phosphaphenanthrene‐10‐oxide (DOPO) derivative (CP‐DOPO) was proposed and synthesized through one‐step Atherton–Todd reaction between DOPO and 4‐cyanophenol. The comprehensive performance analysis of CP‐DOPO‐based EP composite was conducted by measuring the flame retardancy, smoke suppression, and mechanical properties. The flame‐retardant test findings shows that the EP/4CP‐DOPO sample achieves UL‐94 V‐0 rating with 4 wt% low addition of CP‐DOPO. Moreover, EP/6CP‐DOPO sample presents a LOI of 36.5%, a 28.1% reduction in the peak heat release rate, and a 42.1% substantial decrease in total smoke production, demonstrating its desirable flame retardancy and smoke suppression properties. Significantly, different from the traditionally additive flame retardants, the mechanical properties of EP matrix will not be affected by the incorporation of CP‐DOPO but a 17.7% increasement of flexural properties compared to EP. This research not only provides an ingenious strategy for designing and preparing high‐effective flame retardant but also enhances the comprehensive performance of EP resins in practical applications.
Synthesis and characterization of high strength and ultraviolet transmitting silicone rubber reinforced by organic solvent‐soluble trimethylsiloxysilicate polymers (MQ and MTQ copolymers)
Authors: Wu Yu , Qi Yinghao , Liu Weiqi , Zhao Jingshun , Dai Chuanchuan , Li Zhaoxin , Gao Jiaqi , Chen Xuhuang 
Published: April 2024

AbstractAdditional‐type liquid silicone rubber (ALSR) has poor mechanical properties, and conventional methods to reinforce it are at the cost of decreasing transparency. Here, vinyl MQ and fluorine‐containing MTQ silicone resins were synthesized by the sol–gel method. Then, high strength and ultraviolet (UV) transmitting ALSR were prepared using MQ and MTQ silicone resins as reinforcing agents, vinyl‐terminated silicone oil, and polydimethylmethylhydrosiloxane as matrix, respectively. The results show that the enhancement effect of MTQ silicone resin on the mechanical properties of ALSR resin is better than that of MQ silicone resin due to the vinyl content of MTQ silicone resin being higher than that of MQ silicone resin. Compared with pure ALSR, the tensile strength, Young's modulus, and Shore hardness of ALSR with 7 wt% MTQ silicone resin are enhanced by 435%, 127%, and 14%, respectively. The thermal stability of ALSR is slightly increased. The modified silicone rubber also has favorable transparency. Additionally, the MTQ/ALSR composites show higher UV transmittance than MQ/ALSR systems owing to the introduction of fluorine element increasing UV transmittance. The high strength and UV transmittance silicone rubber composites were prepared by using a small addition of MTQ silicone resin.
Comfort levels and experiences of middle school and high school age children in anatomical donor‐based anatomy outreach sessions
Authors: Asri Rijul , Baquerizo Humberto , Padilla‐Register Mercedes , Soto‐Greene Maria L. , Grachan Jeremy J. 
Published: April 2024

AbstractMany health professions schools host anatomy outreach sessions for high school students that utilize anatomical donors. However, teaching with anatomical donors for younger learners is uncommon. This study aimed to assess the comfort levels and experiences of students who attended the anatomy sessions as part of summer programs at Rutgers New Jersey Medical School. Younger learners (students entering grades 7–10; n = 25) and older learners (students entering grades 11–12; n = 33) completed pre‐ and post‐session surveys about their comfort using a 5‐point Likert scale. Before the sessions, most students felt comfortable or very comfortable learning from isolated organs (μ = 2.7, SD = 1.3) or full‐body donors (μ = 2.4, SD = 1.4), even though most have never been to an anatomical donor lab before. After the sessions, the comfort level significantly increased for both isolated organs (μ = 3.3, SD = 1.1; p = 0.02) and full‐body donors (μ = 3.1, SD = 1.2; p = 0.004). For isolated organs, there was no significant difference in the comfort level between younger and older learners before (p = 0.50) or after (p = 0.56) the sessions. Similarly, for full‐body donors, there was no significant difference in the comfort level between younger and older learners before (p = 0.95) or after (p = 0.75) the sessions. Most students expressed that the experience was unique and positive. In conclusion, most students entering grades 7–12 felt comfortable learning from isolated organs and full‐body anatomical donors prior to the sessions and felt more comfortable after the sessions. With this, anatomy outreach programs that utilize anatomical donors could be expanded to include younger learners to provide more dynamic teaching experiences for students of various ages.
Pristine Metal‐Organic Frameworks for Sodium‐Ion Batteries: Past, Present, and Future
Authors: Li Chao , Ni Tao , Yue Min , Li Shujun , Zhang Qichun 
Published: April 2024

AbstractOwing to their adjustable redox‐active sites, designable structures high porosity, and fully activated organic ligands, pristine metal‐organic frameworks (MOFs) have been widely utilized as advanced electrode materials (i. e., both anodes and cathodes) for sodium‐ion batteries (SIBs) to satisfied the insertion/extraction larger size and mass of Na+ cations, achieving significant progresses with excellent electrochemical performance in electrochemical energy storage devices. Here, the recent advances on pristine MOFs as anodes and cathodes for SIBs are summarized. A thorough investigation delves into the detailed characteristics, energy storage mechanisms, and electrochemical performance of diverse pristine MOFs for SIBs are also clarified. Furthermore, the outlooks on pristine MOF electrodes in SIBs are also provided.
Heterochromatin repeat organization at an individual level: Rex1BD and the 14‐3‐3 protein coordinate to shape the epigenetic landscape within heterochromatin repeats
Authors: Gao Jinxin , Li Fei 
Published: April 2024

AbstractIn eukaryotic cells, heterochromatin is typically composed of tandem DNA repeats and plays crucial roles in gene expression and genome stability. It has been reported that silencing at individual units within tandem heterochromatin repeats exhibits a position‐dependent variation. However, how the heterochromatin is organized at an individual repeat level remains poorly understood. Using a novel genetic approach, our recent study identified a conserved protein Rex1BD required for position‐dependent silencing within heterochromatin repeats. We further revealed that Rex1BD interacts with the 14‐3‐3 protein to regulate heterochromatin silencing by linking RNAi and HDAC pathways. In this review, we discuss how Rex1BD and the 14‐3‐3 protein coordinate to modulate heterochromatin organization at the individual repeat level, and comment on the biological significance of the position‐dependent effect in heterochromatin repeats. We also identify the knowledge gaps that still need to be unveiled in the field.
Surface Engineering of BiVO4 Photoanodes for Photoelectrochemical Water Splitting: Recent Advances
Authors: Arunachalam Prabhakarn , Amer Mabrook S. , Al‐Mayouf Abdullah M. , Alsaleh Ahmad A. 
Published: April 2024

AbstractEnergy demand worldwide demands clean, cheap, and renewable energy. Through the use of photoelectrochemical (PEC) conversion, solar energy can be transformed into chemical energy. Bismuth vanadate (BiVO4), a material exhibiting visible light activity, favourable conduction band edge energies, and ease of synthesis, has become increasingly popular in recent years. In BiVO4, charge carriers recombine rapidly, which adversely affects the PEC performance and stability. There have been several strategies developed to mitigate these deficiencies, including novel heterojunctions, doping with metals, coupling with cocatalysts, interface modification and modifying morphology. To achieve the best results, it is required to develop PEC devices with exceptional cost‐to‐efficiency ratios and long‐term durability. This review also examines novel yet commercially viable applications for BiVO4‐based photoanodes. Lastly, we discuss the challenges and perspectives facing PEC water splitting systems based on BiVO4.
An adaptive strategy for time‐varying batch process fault prediction based on stochastic configuration network
Authors: Liu Kai , Zhao Xiaoqiang , Hui Yongyong , Jiang Hongmei 
Published: April 2024

AbstractFault prediction ensures safe and stable production, and cuts maintenance costs. Due to the changing operating conditions that lead to the changes in the characteristics of industrial processes, there is a need to monitor the fault state of batch processes in real‐time and to accurately predict fault trends. An adaptive slow feature analysis‐neighborhood preserving embedding‐improved stochastic configuration network (SFA‐NPE‐ISCN) algorithm for batch process fault prediction is proposed. Firstly, SFA is used to extract the time‐varying features of process data and establish the update index of the NPE model. Then, to extract local nearest‐neighbor features and reconstruct them by the NPE model with adaptive update capability, square prediction error (SPE) statistics are constructed as fault state features based on the reconstructed error. Further, the hunter‐prey optimization (HPO) algorithm optimizes the weights and biases in the stochastic configuration network, and the singular value decomposition (SVD) and QR decomposition of column rotation are introduced to solve the ill‐posed problem of SCN and obtain the prediction model of ISCN. Finally, the obtained statistics SPE is formed into a time series, and the ISCN model is used to predict the process state trend. The effectiveness of the proposed algorithm is verified by case studies of industrial‐scale penicillin fermentation processes and the Hot strip mill process.
Short Peptide and Amino Acid‐Based Supramolecular Ionogels and Eutectogels
Authors: Esteves Carina , Roque Ana Cecília A. 
Published: April 2024

AbstractThe capability of peptide and amino acid‐based molecules to act as ionogelators and eutectogelators entrapping ionic liquids (ILs) and deep eutectic solvents (DESs) forming ionogels and eutectogels has gathered attention in recent decades. The self‐assembly process, primarily driven by non‐covalent interactions as hydrogen bonding, remains serendipitous in nature. This review provides a comprehensive and detailed report on self‐assembly of unmodified and modified amino acids and peptides in the non‐conventional solvents, ILs and DESs. Understanding these processes holds great promise for the development of innovative soft‐materials, and to the progress of supramolecular systems in non‐conventional solvent environments.
Cold Pressing of Perovskite‐ZIF Glass Interpenetrating Networks with Stable Photoelectric Response
Authors: Xia Zhu Hui , Sun Yu Ting , Wei Zhanpeng , Peng Yu , Hou Yu , Yang Shuang 
Published: April 2024

AbstractThe protection of lead halide perovskite within a stable matrix normally leads to the loss of semiconducting properties. Here, we report the synthesis of perovskite‐ZIF glass interpenetrating networks via a cold pressing method, which allows the advantages of bright photoluminescence, high photoconductivity and environmental stability. This hybrid architecture has provided a novel design strategy for the real‐world application of perovskite‐based devices.
PROTOCOL: Methods used in the development, production and updating of evidence and gap maps: A scoping review
Authors: Campbell Fiona , Wong Ruth , Llewellyen Jennifer L. , Stoniute Akvile , Pearson Fiona , Bond Melissa 
Published: April 2024

AbstractEvidence and gap maps (EGMs) are an increasinly popular approach used in evidence synthesis. As an approach they address broad research questions, describing the existing evidence base, highlighting evidence gaps and providing an interactive visual tool for knowledge users. The purpose of this methodological study is to explore the the processes used in the development of EGM's and how they are reported. The aim is to better understand current practice and identify where clearer guidance is needed to support their production.
Hydroxyapatite: An Eco‐Friendly Material for Enzyme Immobilization
Authors: Gelati Leonardo , Rabuffetti Marco , Benaglia Maurizio , Campisi Sebastiano , Gervasini Antonella , Speranza Giovanna , Morelli Carlo F. 
Published: April 2024

AbstractBiocatalysis has emerged in the last decade as a valuable and eco‐friendly tool in chemical synthesis, allowing in several instances to reduce or eliminate the use of hazardous reagents, environmentally dangerous solvents and harsh reaction conditions. Enzymes are indeed able to catalyse chemical transformations on non‐natural substrates under mild reaction conditions, still maintaining their high chemo‐, regio‐, and stereoselectivity. Enzyme immobilization, i. e. the grafting of enzymes on solid supports, can be viewed as an enabling technology, as it allows a better control of the reaction and the recycling of the biocatalyst, thus rendering economically viable the use of expensive enzymes also on a large scale. To pursue a sustainable approach, the supports for enzyme immobilization should be eco‐friendly and possibly renewable. This review highlights the use of hydroxyapatite (HAP), an inorganic biomaterial able to confer strength and stiffness to the bone tissue in animals, as carrier for enzyme immobilization. HAP is a cheap, non‐toxic and biocompatible material, with high surface area and protein affinity. Different enzyme classes, immobilization strategies, and the use of diverse HAP‐based supports will be discussed, underlining the immobilization conditions and the properties of the obtained biocatalysts.
Unveiling stress markers: A systematic review investigating psychological stress biomarkers
Authors: Shah Khushi , Kumari Ruchi , Jain Mukul 
Published: April 2024

AbstractPsychological stress is a ubiquitous facet of modern life, impacting individuals across diverse contexts and demographics. Understanding its physiological manifestations through biomarkers has gained substantial attention within the scientific community. A comprehensive search was conducted across multiple databases for peer‐reviewed articles published within the past decade. Preliminary findings reveal many biomarkers associated with psychological stress across different biological systems, including the hypothalamic–pituitary–adrenal axis, immune system, cardiovascular system, and central nervous system. This systematic review explores psychological, physiological, and biochemical biomarkers associated with stress. Analyzing recent literature, it synthesizes findings across these three categories, elucidating their respective roles in stress response mechanisms. Psychological markers involve subjective assessments like self‐reported stress levels, perceived stress scales, or psychometric evaluations measuring anxiety, depression, or coping mechanisms. Physiological markers include heart rate variability, blood pressure, and immune system responses such as cytokine levels or inflammatory markers. Biochemical markers involve hormones or chemicals linked to stress. It includes cortisol, catecholamines, copeptin, salivary amylase, IL‐6, and C‐reactive protein.