bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcome expectation ratings as predictors of success in weight reduction
Authors: Bradley Ian , Poser Ernest G. , Johnson Jean Ann 
Published: August 2012

AbstractIdentification of obese persons likely to benefit from weight reduction programs presents considerable difficulty. Neither biological (e.g., adipose cellularity) nor psychological (e.g., MMPI profiles) measures thus far have been shown to differentiate reliably between those who do and those who do not lose weight in such programs. Fifteen obese persons about to enter a group program intended to produce “conditioned satiety” were asked to estimate the number of pounds that they expected to lose. Their outcome expectation was found to correlate significantly with weight loss recorded 7 weeks later. However, the magnitude of expected weight loss exceeded the actual amount of weight lost.
Differential effects of hypnosis, biofeedback training, and trophotropic responses on anxiety, ego strength, and locus of control
Authors: Hurley John D. 
Published: August 2012

AbstractPretested 60 college students on three scales: The IPAT Anxiety Scale, the Barron Ego‐strength scale, and the Rotter I‐E scale. The Ss then were assigned randomly to one of four treatment groups designated: Hypnotic treatment, biofeedback treatment, trophotropic treatment, and control. Three of these groups met separately for 60 minutes once a week for 8 weeks. The control group did not meet during this time. During the sessions, each group was trained in a different technique for self‐regulation. At the end of the 8‐week period the scales were readministered to all groups. A series of covariance analyses indicated that hypnosis was a more effective self‐regulatory technique for lowering anxiety levels when compared to biofeedback or trophotropic response procedures. With regard to increasing ego strength, both the hypnotic training group and the biofeedback training group proved to be significant. No significant difference was found between the experimental and control groups on the I‐E scores.
Bidirectional changes in digital skin temperature using biofeedback in a cold room
Authors: Zeiner Arthur R. , Pollak Michael H. 
Published: August 2012

AbstractThe ability to increase digital skin temperature (DST) of cold extremities or to prevent decreases in DST in a cold environment may be useful clinically in the treatment of Raynaud's disease or in the alleviation of the effects of stressful stimuli. Ten Ss, each of whom participated in five sessions, were studied in a room at 20°C. Each session was divided into 5‐minute trials during which Ss either received auditory biofeedback of DST and tried to increase or decrease DST or received no feedback and merely sat quietly (Baseline trials). There were significant changes in DST during Baseline trials; these changes were different at different times during the session. The difference between Increase and Decrease trials was significant. The DST decrease during Decrease trials was significantly different from the change during corresponding Baseline trials, while the Increase trial DST, although of the same magnitude as the decrease trial, did not differ significantly from its corresponding Baseline trials DST.
A comparison of three covert assertion training procedures
Authors: Twentyman Craig T. , Pharr Daniel R. , Connor Jane M. 
Published: August 2012

AbstractAssessed the effectiveness of covert modification procedures in an assertion training program (N = 52). At pretest, Ss chosen on the basis of high scores on an assertion questionnaire were compared to low scoring Ss in a behavioral role play test. Significant differences between these groups were obtained on behavioral ratings. After the pretest, the nonassertive Ss were assigned randomly to a no‐treatment control group or to one of three treatment groups that received covert assertion training procedures. One treatment group received a program that emphasized the generation of alternative responses, while a second group received training directed at restructuring hypothesized negative self‐statements. The third treatment group received a social skills treatment program that employed covert rehearsal procedures. All the treatment groups were superior to the control in behavioral ratings of assertiveness during the posttest in those situations that had been employed previously in treatment; two were superior in those that had not been used and thereby provided evidence of transfer of training. Results are discussed with regard to assessment issues in assertion training programs and the use of cognitively oriented procedures in producing behavioral changes.
Assertion training: Effectiveness in the treatment of depression
Authors: Sanchez Victor C. , Lewinsohn Peter M. , Larson Douglas W. 
Published: August 2012

AbstractAssigned depressed outpatients (N = 32) to either group assertion training or “traditional” group psychotherapy. The results showed that over a relatively short period of time, assertion training was more effective than traditional psychotherapy in increasing self‐reported assertiveness and in alleviating depression.
Three‐year follow‐up data in overweight treatment
Authors: Hautzinger Martin 
Published: August 2012

AbstractReassessed 3 years after the termination of a weight reduction program the body weight of former participants to control long‐term efficiency of behavior‐oriented weight reduction programs. Of 31 former participants, 21 could be rechecked. Most of the Ss stabilized their body weight or continued to reduce weight. Only 4 Ss regained weight over the 3‐year period. On an average, the group of former Ss lost 4.4 kilograms over the follow‐up period. The whole reduction (therapy time and follow‐up) resulted in 11.3 kilograms. These results are encouraging, but difficult to discuss because no member of the former control group could be reassessed after 3 years and 10 Ss of the former therapy‐groups could not be motivated to renewed collaboration. However, these results support the behavior‐oriented approach to weight reduction and give evidence for the stabilizing function of such a therapy.
Levels of psychological experience in asthma: General and illness‐specific concomitants of panic‐fear personality
Authors: Kinsman Robert A. , Dirks Jerald F. , Jones Nelson F. 
Published: August 2012

AbstractCoping styles in asthma indexed by a Panic‐Fear personality measure are known to influence physicians' medical decisions and long‐term treatment outcome. Unusually High or Low Panic‐Fear personality styles are maladaptive, the former characterized by anxious, helpless dependency and the latter by an extreme counterphobic independence. In this study (N = 90), the psychological experiences among Panic‐Fear personality groups (Low, Moderate, and High) of asthma patients are described at three levels of assessment: (1) general personality characteristics; (2) attitudes toward asthma and its treatment; and (3) the subjective symptoms reported during breathing difficulties. Comparisons among the groups delineated the linkages between Panic‐Fear personality and more illness‐specific attitudes, symptoms, and experiences in asthma. Discussion centered upon how general personality and illness‐specific characteristics associated with extreme High and Low Panic‐Fear personality may contribute to the psychomaintenance of asthma.
Therapeutic relationship and improvement as perceived by clients and therapists
Authors: Cooley Eric J. , Lajoy Ronald 
Published: August 2012

AbstractTherapeutic relationship as perceived by clients (N = 54) and therapists (N = 8) at a community mental health clinic was rated on Lorr's (1965) five main factors: Understanding, Accepting, Critical, Independence‐Encouraging, and Authoritarian (Directive). These perceptions were correlated with client and therapist ratings of improvement. In addition, discrepancies between client and therapist ratings of the relationship were correlated with outcome measures. Findings indicated that client perceptions of therapists as Understanding and Accepting were correlated most highly with self‐reported improvement. Therapists self‐perception of Independence‐Encouraging was correlated most highly with client‐rated improvement, while therapists' self‐perception of Accepting and Understanding was correlated most highly with therapist‐rated improvement. Differences between client and therapist ratings of the Understanding and Accepting qualities of the therapeutic relationship showed the highest negative correlations with both client and therapist improvement ratings. Implications for therapeutic and research strategies are discussed.
Perception of self and significant others by male and female alcoholics
Authors: Pushkash Mark , Quereshi M. Y. 
Published: August 2012

AbstractAlcoholic and nonalcoholic adult males and females (N = 100) judged self and three intimate others on four personality characteristics. Multivariate analysis of covariance indicated that alcoholics viewed themselves and their fathers as more unhappy, less sociable, and less productive and persistent; they judged their mothers as more unhappy and less productive and persistent, and they rated their spouses as more unhappy and less sociable than did non‐alcoholics. Also, alcoholics were more variable in their evaluation of self and intimate others.
MMPI profiles and code types of responsible and non‐responsible criminal defendants
Authors: Kurlychek Robert T. , Jordan L. 
Published: August 2012

AbstractCompared MMPI profiles and two‐point code types of criminal defendants (N = 50) who were pleading a defense of “not responsible due to mental disease or defect.” In examining the mean, non‐K corrected raw scores, no significant differences were found between those defendants determined responsible and those determined non‐responsible on individual MMPI scales. A sign test was computed, treating the clinical scales as matched pairs, and a significant difference was found; the non‐responsible group profile was more elevated. Two‐point codes were determined for each group member, and the percentages of individuals within each group who had the same two‐point codes were calculated. A chi‐square test was significant, which indicates that there is an association between the classification of an individual and the two‐point code produced. The 8‐7 code type was modal for the responsible group, while the 8‐6 code type was modal for the non‐responsible group. These findings are discussed, and future research directions in this area are suggested.
The adolescent antisocial behavior check list
Authors: Ostrov Eric , Marohn Richard C. , Offer Daniel , Curtiss Glenn , Feczko Mary 
Published: August 2012

AbstractDescribed the development and validation of a behavioral checklist that focuses on adolescent inpatient (N = 55) antisocial behavior. Reliability data and three sub‐studies that tend to establish the validity of this instrument as a measure of antisocial behavior were presented. The implications for the study of adolescent antisocial behavior as a dependent variable were discussed.
Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene
Authors: Hovhannisyan Hayk , Zhang Ying , Hassan Mohammad Q. , Wu Hai , Glackin Carlotta , Lian Jane B. , Stein Janet L. , Montecino Martin , Stein Gary S. , van Wijnen Andre J. 
Published: August 2012

AbstractEpigenetic mechanisms mediating expression of the Runt‐related transcription factor Runx2 are critical for controlling its osteogenic activity during skeletal development. Here, we characterized bona fide regulatory elements within 120 kbp of the endogenous bone‐related Runx2 promoter (P1) in osteoblasts by genomic DNase I footprinting and chromatin immuno‐precipitations (ChIPs). We identified a ∼10 kbp genomic domain spanning the P1 promoter that interacts with acetylated histones H3 and H4 reflecting an open chromatin conformation in MC3T3 osteoblasts. This large chromatin domain contains a single major DNaseI hypersensitive (DHS) region that defines a 0.4 kbp “basal core” promoter. This region encompasses two endogenous genomic protein/DNA interaction sites (i.e., footprints at Activating Protein 1 [AP1], E‐box and Runx motifs). Helix‐Loop‐Helix (HLH)/E‐box occupancy and presence of the DHS region persists in several mesenchymal cell types, but AP1 site occupancy occurs only during S phase when Runx2 expression is minimal. Point‐mutation of the HLH/E box dramatically reduces basal promoter activity. Our results indicate that the Runx2 P1 promoter utilizes two stable principal protein/DNA interaction domains associated with AP1 and HLH factors. These sites function together with dynamic and developmentally responsive sites in a major DHS region to support epigenetic control of bone‐specific transcription when osteoblasts transition into a quiescent or differentiated state. J. Cell. Physiol. 228: 313–321, 2013. © 2012 Wiley Periodicals, Inc.
Chromatin dynamics in living cells: Identification of oscillatory motion
Authors: Pliss Artem , Malyavantham Kishore S. , Bhattacharya Sambit , Berezney Ronald 
Published: August 2012

AbstractGenomic DNA in mammalian cells is organized into ∼1 Mbp chromatin domains (ChrD) which represent the basic structural units for DNA compaction, replication, and transcription. Remarkably, ChrD are highly dynamic and undergo both translational movement and configurational changes. In this study, we introduce an automated motion tracking analysis to measure, both in 2D and 3D, the linear displacement of early, mid and late S‐phase replicated ChrD over short time periods (<1 sec). We conclude that previously identified large‐scale transitions in the spatial position and configuration of chromatin, originate from asymmetric oscillations of the ChrD detectable in fractions of a second. The rapid oscillatory motion correlates with the replication timing of the ChrD with early S replicated ChrD showing the highest levels of motion and late S‐phase chromatin the lowest. Virtually identical levels of oscillatory motion were detected when ChrD were measured during active DNA replication or during inhibition of transcription with DRB or α‐amanitin. While this motion is energy independent, the oscillations of early S and mid S, but not late S replicated chromatin, are reduced by cell permeabilization. This suggests involvement of soluble factors in the regulation of chromatin dynamics. The DNA intercalating agent actinomycin D also significantly inhibits early S‐labeled chromatin oscillation. We propose that rapid asymmetric oscillations of <1 sec are the basis for translational movements and configurational changes in ChrD previously detected over time spans of minutes–hours, and are the result of both the stochastic collisions of macromolecules and specific molecular interactions. J. Cell. Physiol. 228: 609–616, 2013. © 2012 Wiley Periodicals, Inc.
An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells
Authors: Kim Jung‐Min , Choi Jin Seok , Kim Yun‐Hee , Jin Seong Hui , Lim Seyoung , Jang Hyun‐Jun , Kim Kyong‐Tai , Ryu Sung Ho , Suh Pann‐Ghill 
Published: August 2012

AbstractMesenchymal stem cells (MSCs) are multipotent adult stem cells capable of differentiating along the osteoblast, adipocyte, and chondrocyte lineages. Regulation of MSCs differentiation may be a useful tool for regenerative medicine and cell‐based therapy. The discovery of small molecule that activates the osteogenic differentiation of MSCs could aid in the development of a new anabolic drug for osteoporosis treatment. We identified CW008, a derivative of pyrazole–pyridine, that stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion. These results suggest that CW008 is an agonist of cAMP/PKA/CREB pathway in osteogenic differentiation and that application of CW008 may be useful for the treatment of bone‐related diseases and for the study of bone biology. J. Cell. Physiol. 228: 617–626, 2013. © 2012 Wiley Periodicals, Inc.
Comparison of gait in patients following a computer‐navigated minimally invasive anterior approach and a conventional posterolateral approach for total hip arthroplasty: A randomized controlled trial
Authors: Reininga Inge H.F. , Stevens Martin , Wagenmakers Robert , Boerboom Alexander L. , Groothoff Johan W. , Bulstra Sjoerd K. , Zijlstra Wiebren 
Published: August 2012

AbstractMinimally invasive total hip arthroplasty (MIS THA) aims at minimizing damage to muscles and tendons to accelerate postoperative recovery. Computer navigation allows a precise prosthesis alignment without complete visualization of the bony landmarks during MIS THA. A randomized controlled trial (RCT) was conducted to determine the effectiveness of a computer‐navigated MIS anterior approach for THA compared to a conventional posterolateral THA technique on the restoration of physical functioning during recovery following surgery. Thirty‐five patients underwent computer‐navigated MIS THA via the anterior approach, and 40 patients underwent conventional THA using the conventional posterolateral approach. Gait analysis was performed preoperatively, 6 weeks, and 3 and 6 months postoperatively using a body‐fixed‐sensor based gait analysis system. Walking speed, step length, cadence, and frontal plane angular movements of the pelvis and thorax were assessed. The same data were obtained from 30 healthy subjects. No differences were found in the recovery of spatiotemporal parameters or in angular movements of the pelvis and thorax following the computer‐navigated MIS anterior approach or the conventional posterolateral approach. Although gait improved after surgery, small differences in several spatiotemporal parameters and angular movements of the trunk remained at 6 months postoperatively between both patient groups and healthy subjects. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 31: 288–294, 2013
Intraoperative C‐arm cone‐beam computed tomography: Quantitative analysis of surgical performance in skull base surgery
Authors: Lee Stella , Gallia Gary L. , Reh Douglas D. , Schafer Sebastian , Uneri Ali , Mirota Daniel J. , Nithiananthan Sajendra , Otake Yoshito , Stayman J. Webster , Zbijewski Wojciech , Siewerdsen Jeffrey H. 
Published: August 2012

AbstractObjectives/Hypothesis:To determine whether incorporation of intraoperative imaging via a new cone‐beam computed tomography (CBCT) image‐guidance system improves accuracy and facilitates resection in sinus and skull‐base surgery through quantification of surgical performance.Study Design:Landmark identification and skull base ablation tasks were performed with a CBCT intraoperative image‐guidance system in the experimental group and with image‐guided surgery (IGS) alone based on preoperative computed tomography (CT) in the control group.Methods:Six cadaveric heads underwent preoperative CT imaging and surgical planning identifying surgical targets. Three types of surgical tasks were planned: landmark point identification, line contour identification, and volume drill‐out. Key anatomic structures (carotid artery and optic nerve) were chosen for landmark identification and line contour tasks. Complete ethmoidectomy, vidian corridor drill‐out, and clival resection were performed for volume ablation tasks. The CBCT guidance system was used in the experimental group and performance was assessed by metrics of target registration error, sensitivity, and specificity of excision.Results:Significant improvements were seen for point identification and line tracing tasks. Additional resection was performed in 67% of tasks in the CBCT group, and qualitative feedback indicated unequivocal improvement in confidence for all tasks. In review of tasks in the control group, additional resection would have been performed in 35% of tasks if an intraoperative image was available.Conclusions:An experimental prototype C‐arm CBCT guidance system was shown to improve surgical precision in the identification of skull base targets and increase accuracy in the ablation of surgical target volumes in comparison to using IGS alone.
Halloysite Clay Nanotubes for Resveratrol Delivery to Cancer Cells
Authors: Vergaro Viviana , Lvov Yuri M. , Leporatti Stefano 
Published: August 2012

AbstractHalloysite is natural aluminosilicate clay with hollow tubular structure which allows loading with low soluble drugs using their saturated solutions in organic solvents. Resveratrol, a polyphenol known for having antioxidant and antineoplastic properties, is loaded inside these clay nanotubes lumens. Release time of 48 h is demonstrated. Spectroscopic and ζ‐potential measurements are used to study the drug loading/release and for monitoring the nanotube layer‐by‐layer (LbL) coating with polyelectrolytes for further release control. Resveratrol‐loaded clay nanotubes are added to breast cell cultures for toxicity tests. Halloysite functionalization with LbL polyelectrolyte multilayers remarkably decrease nanotube self‐toxicity. MTT measurements performed with a neoplastic cell lines model system (MCF‐7) as function of the resveratrol‐loaded nanotubes concentration and incubation time indicate that drug‐loaded halloysite strongly increase of cytotoxicity leading to cell apoptosis. magnified image
Emergence of Polymer Stereocomplexes for Biomedical Applications
Authors: Bertin Annabelle 
Published: August 2012

AbstractPolylactide (PLA) and poly(methyl methacrylate) (PMMA) constitute, already for several decades, the gold standards for various biomedical applications due to their biocompatibility/inertness. Moreover, they have an additional property: they can form stereocomplexes (SCs) that have a more compact crystalline structure than the individual components. As a result, polymer SCs display improved thermal and mechanical properties, as well as delayed drug release and biodegradation rate in the case of drug delivery systems and biomaterials based on PLA, which is of prime importance in the biomedical field. In this article, the potential of SCs for biomedical applications in the areas of drug delivery, tissue engineering, and nanostructured surfaces is highlighted.
Preparation of Fluorescent Conjugated Polymer Films with Different Emission Colors: Investigation into the Influences of Chemical Structure and Morphology
Authors: Zhao Wei , Song Jing , Shao Ya , Zhang Wei , Au Aaron , Fan Li‐Juan 
Published: August 2012

AbstractA series of PPV films with different fluorescent emission colors are prepared using a facile approach. Modified from the conventional Wessling route, the labile sulfonium groups in the polymer precursor (pre‐PPV) are partly substituted to various degrees by relatively stable methoxy groups, followed by a regular thermal elimination step to obtain PPV. Different chemical structures among these films are confirmed by IR and photophysical studies. Two film‐preparative processes are compared and the films are studied by SEM and confocal fluorescent microscopy. From the same polymer precursor, different preparative processes result in PPV films with different morphologies but the same photophysical properties.