bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative ultrasound in colorectal surgery
Authors: Greif Franklin , Aranovich David , Hananel Nissim , Knizhnik Mikhail , Belenky Alexander 
Published: May 2009

AbstractPurpose.To assess the accuracy of intraoperative ultrasound (IOUS) as a localizing technique for colorectal resections, and its impact on surgical management.Methods.Twenty‐five patients (15 men and 10 women; mean age, 74.4 years) with early cancers (p T1), or polyps, not amenable to endoscopic removal were selected. IOUS was used as a sole method of intraoperative localization. Its performance was evaluated through review of preoperative colonoscopy reports, intraoperative findings, histopathology reports, and clinical follow‐up.Results.The lesions were situated in the cecum (n = 5), ascending colon (n = 3), transverse colon (n = 4), descending colon (n = 7), and rectum (n = 6). IOUS technique allowed correct localization in 24 of 25 patients, visualization of the bowel wall, and its penetration by malignant tumors. In rectal lesions, IOUS showed clearly the tumor and its margin, which facilitated performance sphincter‐sparing procedure.Conclusion.In patients with small polyps and early cancers of colon and rectum, IOUS may be effectively used as a sole method of intraoperative localization and provide additional information that may alter decision making with regard to surgical technique. © 2009 Wiley Periodicals, Inc. J Clin Ultrasound, 2009
Sonography versus nerve conduction studies in patients referred with a clinical diagnosis of carpal tunnel syndrome
Authors: Pastare D. , Therimadasamy A.K. , Lee E. , Wilder‐Smith E.P. 
Published: May 2009

AbstractPurpose.To compare the diagnostic value of high‐resolution ultrasound (US) with nerve conduction studies (NCS) in patients with clinically defined carpal tunnel syndrome (CTS).Methods.A prospective study was conducted on 66 consecutive patients investigated for sensory hand symptoms. The gold standard was the clinical diagnosis of CTS.Results.NCS showed greater diagnostic sensitivity (82%) than US (62%) in supporting a diagnosis of CTS. With increasing neurophysiologic severity of median neuropathy, there was increasing convergence of the two test methods. Abnormal US as the only diagnostic supportive evidence of CTS was rare. However, the positive predictive value of US for CTS was 100%.Conclusion.NCS show better sensitivity than US in supporting a diagnosis of CTS. However, because of its high positive predictive value, one may consider using US as a screening test, eliminating the need for NCS in the majority of clinical suspicion of CTS and reserving NCS for cases in which US is negative. © 2009 Wiley Periodicals, Inc. J Clin Ultrasound, 2009
A facile synthesis of furo[3,4‐e]pyrazolo[3,4‐b]pyridine‐5(7H)‐one derivatives via three‐component reaction in ionic liquid without any catalyst
Authors: Shi Da‐Qing , Yang Fang , Ni Sai‐Nan 
Published: May 2009

Abstractmagnified imageA series of furo[3,4‐e]pyrazolo[3,4‐b]pyridine‐5(7H)‐one and indeno[2,1‐e]pyrazolo[3,4‐b]pyridine‐5(1H)‐one derivatives were synthesized via the three‐component reaction of an aldehyde, 5‐aminopyrazole and either tetronic acid or 1,3‐indanedione in ionic liquid without any catalyst. The structures of the products have been established by spectroscopic data and further confirmed by X‐ray diffraction analysis. This method has the advantages of easier work‐up, mild reaction conditions, high yields and an environmentally benign procedure. J. Heterocyclic Chem., 46, 469 (2009).
Improved preparation of 3‐(1,1‐dimethylallyl)decursinol
Authors: Jiang Xiangrui , Li Jianfeng , Zhang Rongxia , Guo Hongli , Huang Shaolei , Shen Jingshan 
Published: May 2009

Abstract
magnified imageAn improved preparation method of 3‐(1,1‐dimethylallyl)decursinol from inexpensive commercially available start material was described. In the cyclization of 13, silica gel was used as catalyst to give 1 with high purity and satisfying yield. J. Heterocyclic Chem., 46, 560 (2009).
Synthesis and antimicrobial studies of novel bis(diamino)thiazoles
Authors: Manju Sreedharan L. , Devi Satyabhama K. C. , Rajasekharan Kallikat N. 
Published: May 2009

Abstract
magnified imageThe synthesis of novel bis(diamino)thiazoles has been achieved by reacting bis(bromoacetyl)benzene and 1‐alkyl(or aryl)‐3‐(N‐nitroamidino)thioureas in presence of triethylamine. These new compounds were characterized by spectral analysis and screened for antimicrobial activities. J. Heterocyclic Chem., 46, 455 (2009).
Unexpected CO bond formation in Suzuki coupling of 4‐chlorothieno[2,3‐d]pyrimidines
Authors: Perspicace Enrico , Hesse Stéphanie , Kirsch Gilbert , Yemloul Mehdi , Lecomte Claude 
Published: May 2009

Abstract
magnified imagePalladium‐catalyzed Suzuki reactions were performed on 4‐chlorothieno[2,3‐d]pyrimidines under classical heating conditions and under microwave irradiation. Some unexpected results were obtained during this study as two kinds of compounds were isolated depending on the conditions used. A careful investigation of experimental details has shown that the expected CC bond formation occurred when degassed solvents were used (both in classical and microwave heating) whereas an unexpected CO bond formation happened when solvents were not degassed with argon‐bubbling before use. J. Heterocyclic Chem., 46, 459 (2009).
Solvent‐free microwave‐assisted synthesis of 1H‐indole‐2, 3‐dione derivatives
Authors: Singh Ashish Kumar , Shukla Sudhish Kumar , Ahamad Ishtiaque , Quraishi M. A. 
Published: May 2009

Abstract
magnified imageMicrowave‐assisted synthesis has been found to increase both reaction rates and yields via more efficient heating compared with standard thermal conduction. Dry reaction of isatins with thiosemicarbazide and their thiosemicarbazone with secondary amine on acid—washed K10 in microwave oven afforded isatin‐3‐thiosemicarbazones and N‐Mannich bases in reasonably good yield. The chemical structures were confirmed by means of 1H NMR, IR spectral data, and elemental analysis. J. Heterocyclic Chem., 46, 571 (2009).
Synthesis and spectral characterization of a novel series of methylcinnamate derivatives of 15‐crown‐5
Authors: Gündüz Cihan , Salan Ümit , Bulut Mustafa 
Published: May 2009

Abstract
magnified imageA series of novel methylcinnamate derivatives of 15‐crown‐5 have been synthesized. The derivatives of methylcinnamate have been prepared by a synthesis from the corresponding chromenone‐crown ether with MeONa/MeOH or KOH, CH3I, and DMSO as solvent. Novel compounds were characterized by elemental analysis, IR, 1H NMR, and MALDI‐TOF. J. Heterocyclic Chem., 46, 567 (2009).
In situ vinylpyrrole synthesis. Diels‐Alder reactions with maleimides to give tetrahydroindoles
Authors: Noland Wayland E. , Lanzatella Nicholas P. , Sizova Elena P. , Venkatraman Lakshmanan , Afanasyev Oleg V. 
Published: May 2009

Abstract
magnified imageA series of 108 tetrahydroindoles has been prepared by a one‐pot synthesis from 2‐alkylpyrroles, cyclic ketones, maleimides, and an acid catalyst. A 5‐vinylpyrrole is formed by an acid‐catalyzed condensation of a 2‐alkyl‐substituted pyrrole with a ketone, which is subsequently trapped in situ by a maleimide in a predominantly endo‐addition Diels‐Alder reaction. Isomerization of the double bond into the pyrrole ring gives a tetrahydroindole with predominant cis‐fusion of the cycloalkane ring. J. Heterocyclic Chem., 46, 503 (2009).
Transitions of Care Consensus Policy Statement: American College of Physicians, Society of General Internal Medicine, Society of Hospital Medicine, American Geriatrics Society, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Authors: Snow Vincenza , Beck Dennis , Budnitz Tina , Miller Doriane C. , Potter Jane , Wears Robert L. , Weiss Kevin B. , Williams Mark V. 
Published: May 2009

AbstractThe American College of Physicians, Society of Hospital Medicine, and Society of General Internal Medicine convened a multi‐stakeholder consensus conference in July 2007 to address the quality gaps in the transitions between inpatient and outpatient settings and to develop consensus standards for these transitions. Over 30 organizations sent representatives to the Transitions of Care Consensus Conference. Participating organizations included medical specialty societies from internal medicine as well as family medicine and pediatrics, governmental agencies such as the Agency for Healthcare Research and Quality and the Centers for Medicare and Medicaid Services, performance measure developers such as the National Committee for Quality Assurance and the American Medical Association Physician Consortium on Performance Improvement, nurse associations such as the Visiting Nurse Associations of America and Home Care and Hospice, pharmacist groups, and patient groups such as the Institute for Family‐Centered Care. The Transitions of Care Consensus Conference made recommendations for standards concerning the transitions between inpatient and outpatient settings for future implementation. The American College of Physicians, Society of Hospital Medicine, Society of General Internal Medicine, American Geriatric Society, American College of Emergency Physicians, and Society for Academic Emergency Medicine all endorsed this document. Journal of Hospital Medicine 2009;4:364–370. © 2009 Society of Hospital Medicine.
Synthesis, radiosynthesis andin vivoevaluation of [123I]‐4‐(2‐(bis(4‐fluorophenyl)methoxy)ethyl)‐1‐(4‐iodobenzyl)piperidine as a selective tracer for imaging the dopamine transporter
Authors: De Bruyne S. , Boos T. L. , wyffels L. , Goeman J. L. , Rice K. C. , De Vos F. 
Published: May 2009

AbstractDopamine transporter (DAT) neuroimaging is a useful tool in Parkinson's disease diagnosis, staging and follow‐up providing information on the integrity of the dopaminergic neurotransmitter systemin vivo. 4‐(2‐(Bis(4‐fluorophenyl)methoxy)ethyl)‐1‐(4‐iodobenzyl)piperidine (7) has nanomolar affinity for DAT and better selectivity over the other monoamine transporters compared with the existing SPECT radioligands for DAT. The aim of this study was to synthesize and evaluate [123I]‐7 as anin vivotracer for DAT.The tributylstannyl precursor was synthesized with an overall yield of 25%. [123I]‐7 was synthesized by electrophilic destannylation with a yield of 40±10%. Radiochemical purity appeared to be >98%, whereas specific activity was at least 667 GBq/µmol. Biodistribution studies in mice showed brain uptake of 0.96±0.53%ID/g at 30 s post injection (p.i.) and 0.26±0.02%ID/g at 3 h p.i. High blood activity was observed at all time points. Pretreatment with Cyclosporin A raised brain uptake indicating that [123I]‐7 is transported by P‐glycoprotein (P‐gp) pumps. In rats, regional brain distribution of [123I]‐7 was not in agreement with DAT distribution. These results indicate that [123I]‐7 is not suitable for mapping DATin vivobut could be a useful tracer for the P‐gp transporter. Copyright © 2009 John Wiley & Sons, Ltd.
Deuterium labelling of theaflavin
Authors: Peng Weimin , Yao Yin‐fang 
Published: May 2009

AbstractAn efficient deuterium labelling of theaflavin, aiming at radiolabelling of theaflavin, was accomplished for the first time by using 4‐deuterium‐labelled epi‐catechin as the precursor and the resulting D‐labelled theaflavin was fully characterized by 1H NMR, 13C NMR, IR spectroscopy and ESI‐MS. The synthesis features a novel efficient polyphenol oxidase (PPO) catalyzed benzotropolone formation. PPO was bound onto a selected polymer by a novel efficient method developed in this lab. Copyright © 2009 John Wiley & Sons, Ltd.
Understanding the elements of empathy as a component of care‐driven leadership
Authors: Undung Yosep , De Guzman Allan B. 
Published: May 2009

AbstractEmpathy plays a pivotal role in educational leadership practice. It creates and maintains a sound and dynamic interpersonal milieu in dynamic social enterprises such as schools, colleges, and universities. A phenomenological study was conducted to probe deeper the meaning of empathy as it is lived and constituted in the awareness of a select group of 13 Filipino academic administrators representing colleges in the Philippines. Anchored on the central question, “how do Filipino academic administrators collectively typify in their school leadership practices the elements of empathic concern, perspective taking, and empathic matching,” semistructured (Patton, 1990) and in‐depth interviews were conducted. Field texts were analyzed via a repertory grid. Through constant comparative analyses, an interesting set of conceptual categories notably describes the human and humane side of a caring leader, typified in the ability to effect listening, confluencing, and scaffolding in the journey with the faculty.
Assessing the value of the relationship between organizational culture types and knowledge management initiatives
Authors: Kangas Lisa M. 
Published: May 2009

AbstractThis mixed‐methods study assessed the relationship between organizational culture type and continuous knowledge management initiatives in a prominent global company in the transportation industry. The two‐part sequential phase of grounded theory included triangulation through collection and analysis of quantitative data from a questionnaire followed by collection and analysis of qualitative data from interviews, observations, and documents. The theory emerged from the findings, and the results of this research study revealed the importance for leaders of assessing their organizational culture type as it relates to continuous knowledge management initiatives. Research indicates that it is imperative for leaders to understand organizational culture types for long‐term success to occur. By generating the right organizational culture and continuous knowledge management initiatives, leaders will enhance value and help increase an organization's competitive advantage.
Are you a net creator or destroyer of talent? Seven indicators of organizational health for talent‐intensive organizations
Authors: Harro Ted , Miller Leslie A. 
Published: May 2009

AbstractAs far back as the ninth century BCE in Greece, a talent was a form of currency. In the 21st century, talents remain currency as the special gifts of knowledge, skills, and personal characteristics that individuals bring to organizations. Talent management, also known as human capital management, HCM, is a focus of leadership studies that increasingly strives to acknowledge and measure the tangible contributions that individuals make to the bottom line. In this symposium, we offer a position paper by Ted Harro and Leslie Miller who detail an innovative approach to address how leaders of organizations can create a consistent, positive flow of talent necessary to support success. Our respondents, Karen Kirwan, Dave Wondra, and Edward Perez, each add their perspectives to this timely discussion.
Talent and the human spirit
Authors: Wondra Dave 
Published: May 2009

AbstractAs far back as the ninth century BCE in Greece, a talent was a form of currency. In the 21st century, talents remain currency as the special gifts of knowledge, skills, and personal characteristics that individuals bring to organizations. Talent management, also known as human capital management, HCM, is a focus of leadership studies that increasingly strives to acknowledge and measure the tangible contributions that individuals make to the bottom line. In this symposium, we offer a position paper by Ted Harro and Leslie Miller who detail an innovative approach to address how leaders of organizations can create a consistent, positive flow of talent necessary to support success. Our respondents, Karen Kirwan, Dave Wondra, and Edward Perez, each add their perspectives to this timely discussion.
Choosing the right people and developing them
Authors: Perez Edward C. 
Published: May 2009

AbstractAs far back as the ninth century BCE in Greece, a talent was a form of currency. In the 21st century, talents remain currency as the special gifts of knowledge, skills, and personal characteristics that individuals bring to organizations. Talent management, also known as human capital management, HCM, is a focus of leadership studies that increasingly strives to acknowledge and measure the tangible contributions that individuals make to the bottom line. In this symposium, we offer a position paper by Ted Harro and Leslie Miller who detail an innovative approach to address how leaders of organizations can create a consistent, positive flow of talent necessary to support success. Our respondents, Karen Kirwan, Dave Wondra, and Edward Perez, each add their perspectives to this timely discussion.
Surviving submerged—Setal tracheal gills for gas exchange in adult rheophilic diving beetles
Authors: Kehl Siegfried , Dettner Konrad 
Published: May 2009

AbstractThe gas exchange in adult diving beetles (Coleoptera: Dytiscidae) relies on a subelytral air store, which has to be renewed in regular intervals at the water surface. The dive duration varies from a few minutes to 24 h depending on the species, activity, and temperature. However, some species remain submerged for several weeks. Stygobiont species do not ascend to the surface and gas exchange of these species remains unclear, but it is assumed that they require air filled voids for respiration or they use cutaneous respiration. In this study, we investigate the gas exchange in the running water diving beetle Deronectes aubei, which survive submerged for over 6 weeks. The diffusion distance through the cuticle is too great for cutaneous respiration. Therefore, the dissolved oxygen uptake of submerged beetles was determined and an oxygen uptake via the rich tracheated elytra was observed. Fine structure analyses (SEM and TEM) of the beetles showed tracheated setae mainly on the elytral surface, which acts as tracheal gills. Prevention of the air bubble formation at the tip of the abdomen, which normally act as physical gill in Dytiscidae, resulted in no effect in oxygen uptake in D. aubei, but this was the sole way for a submerged Hydroporus palustris to get oxygen. The setal gas exchange technique explains the restriction of D. aubei to rivers and brooks with high oxygen concentration and it may also be used by subterran living diving beetles, which lack access to atmospheric oxygen. The existence of setal tracheal gills in species in running water which are often found in the hyporheic zone and in stygobiont species supports the known evolution of stygobiont Dytiscidae from species of the hyporheic zone. For species in running water, setal tracheal gills could be seen as an adaptation to avoid drifting downstream by the current. J. Morphol., 2009. © 2009 Wiley‐Liss, Inc.
A real‐time PCR assay to identify and discriminate among wild‐type and vaccine strains of varicella‐zoster virus and herpes simplex virus in clinical specimens, and comparison with the clinical diagnoses
Authors: Harbecke Ruth , Oxman Michael N. , Arnold Beth A. , Ip Charlotte , Johnson Gary R. , Levin Myron J. , Gelb Lawrence D. , Schmader Kenneth E. , Straus Stephen E. , Wang Hui , Wright Peter F. , Pachucki Constance T. , Gershon Anne A. , Arbeit Robert D. , Davis Larry E. , Simberkoff Michael S. , Weinberg Adriana , Williams Heather M. , Cheney Carol , Petrukhin Luba , Abraham Katalin G. , Shaw Alan , Manoff Susan , Antonello Joseph M. , Green Tina , Wang Yue , Tan Charles , Keller Paul M. ,   for the Shingles Prevention Study Group
Published: May 2009

AbstractA real‐time PCR assay was developed to identify varicella‐zoster virus (VZV) and herpes simplex virus (HSV) DNA in clinical specimens from subjects with suspected herpes zoster (HZ; shingles). Three sets of primers and probes were used in separate PCR reactions to detect and discriminate among wild‐type VZV (VZV‐WT), Oka vaccine strain VZV (VZV‐Oka), and HSV DNA, and the reaction for each virus DNA was multiplexed with primers and probe specific for the human β‐globin gene to assess specimen adequacy. Discrimination of all VZV‐WT strains, including Japanese isolates and the Oka parent strain, from VZV‐Oka was based upon a single nucleotide polymorphism at position 106262 in ORF 62, resulting in preferential amplification by the homologous primer pair. The assay was highly sensitive and specific for the target virus DNA, and no cross‐reactions were detected with any other infectious agent. With the PCR assay as the gold standard, the sensitivity of virus culture was 53% for VZV and 77% for HSV. There was 92% agreement between the clinical diagnosis of HZ by the Clinical Evaluation Committee and the PCR assay results. J. Med. Virol. 81:1310–1322, 2009. Published 2009 Wiley‐Liss, Inc.
A comparative study of the frequency of antibody and titers against human herpesvirus 8 latent and lytic antigens in “at‐risk” individuals and among patients with Kaposi's sarcoma
Authors: Magri Mariana Cavalheiro , Carbone Paulo Henrique Lage , de los Santos‐Fortuna Elizabeth , Caterino‐de‐Araujo Adele 
Published: May 2009

AbstractDifferences in the prevalence of human herpesvirus 8 (HHV‐8) and Kaposi's sarcoma (KS) have been described, depending on the study population and their geographic origin. A cross‐ sectional study aimed at detecting the frequency and titers of antibodies against HHV‐8 latent and lytic antigens in serum samples from individuals with different risk‐factors for HHV‐8 infection, as well as predictive marker identification in patients with KS, was conducted. Serum samples were collected from seven groups of individuals: 75 patients with AIDS‐KS, 5 with classic KS, 16 with African KS, 495 with HIV/AIDS, 805 patients with chronic kidney disease, 683 handicapped individuals, and 757 health care workers. Samples were evaluated for the presence and titers of HHV‐8‐specific antibodies to latent and lytic antigens using “in house” immunofluorescence assays. The results were analyzed by the Chi‐square, Fisher's exact test, Kruskal–Wallis and/or Mann–Whitney U‐tests. The frequencies of HHV‐8 antibodies were as follows: 87.5–100% in patients with KS, 20.4% in patients with HIV/AIDS, 18% in patients with chronic kidney disease, 1.6% in handicapped individuals, and 1.1% in health care workers. A greater number of samples were antibody positive to lytic antigens. Elevated titers of antibodies to latent and lytic antigens, mostly among patients with KS, were detected. Using established serological assays, different “at‐risk” populations for HHV‐8 infection/disease were detected in this geographic area, confirming HIV/AIDS and identifying patients with chronic kidney disease as high‐risk groups. It is suggested that a longitudinal evaluation of antibody titers in patients with chronic kidney disease be undertaken to confirm their predictive value in the development of KS. J. Med. Virol. 81:1292–1297, 2009. © 2009 Wiley‐Liss, Inc.