bluuebunny/crossref_metadata_2025_split huggingface dataset:
74: HOW CLINICAL LIBRARIAN ACTS IN EVIDENCE-BASED MEDICINE? A SYSTEMATIC REVIEW
Authors: Mojgan Zareivenovel , Abdlorasoul khosravi 
Published: May 2024

Background and aims:The rapid growth and specialization in Medical Sciences increase the volume of information and therefore make physician problems and difficulty to access reliable information. Physicians can`t decide only according to self-knowledge, and should refer to the new texts and references. Clinical librarian role as a key chain in evidence-based medicine can`t be ignored. Clinical librarian at the hospital library works as a specialist and come to help physicians to carry out evidence-based medicine process in the shortest time and with the least effort. The aim of this study was clarify status and importance of the clinical librarian in the process of evidence-based medicine.Methods:This was a systematic study. Electronic databases such as clinical key, Medline, Embase, Cochrane, Conference proceedings & abstract books, Hand searching, raw data from published trials and thesis were analyzed by keywords: medical librarian, clinical librarianship and informationist. The period which gather information was from 2000–2015 and 112 articles selected, finally 65 were chosen to considered according to inclusion criteria includes the role of medical librarian and article in English and Persian.Results:Clinical librarian Provide filtered information to clinician at the point of need to promote evidence-based health care. Moreover, overcome the time, cost and expertise barriers that clinicians face when they attempt to incorporate the best current evidence from the literature into their patient care decisions, enhance the educational experience of students and resident physicians in training. The position is helping physicians to make decisions based on evidence and access to reliable information is not well understood in our country. Evidence-Based Medicine and librarian in the modern era needs the help their.Conclusion:In the health sector, especially in hospital library, clinical librarian position in evidence-based practice is not well established and many studies must be done in this area in the future. Dissertation thesis will be done and Policies should be considered in this area. Clinical librarian in hospital libraries can be used as a key element in the process of evidence-based medicine.
84: IS HOSPITALIZATION RATE ASSOCIATED WITH SEXUALITY? A TIME-PERIOD STUDY IN THE LARGEST REFERRAL HOSPITAL IN NORTHWEST OF IRAN
Authors: Talebpour Amin , Ghogazadeh Morteza , Ghodrati Parisa , Rezaie Zohreh 
Published: May 2024

Background and aims:The hospitalization rate differences between male and female patients could facilitate management of hospital wards and enhance their efficiency. The aim of this study was to determine the association between sexuality and hospitalization rate by annual hospitalization statistics of one of the Tabriz University of Medical Sciences hospitals according to hospitalization wards.Methods:A Cross-sectional study was conducted. All 30260 records of hospitalized patients of Imam Reza referral Hospital in 1393 included in the study. Data was extracted based on a checklist designed by authors. In order to determine the relations between the variables, Chi-Square test was applied and the P-value was considered less than 0.05. The obtained data were analyzed by software SPSS.16.Results:Of 30260 Cases, 52.26% were male and 47.73% were female. There was no significant difference among male and female hospitalized patients. The highest hospitalization rate for men was in the orthopedics ward with 20.04% (3302 of 16158 male patients) while it was 14.2% (3054 of 13877 female patients) for women in surgery ward. The least significant statistical difference between male and female hospitalization rates was observed in renal ward with 49.85% (683 patients) male and 50.15% (687 patients) female of total patients hospitalized in this ward. The significant statistical difference between male and female hospitalization rates was observed in orthopedic with 71.31% (3302 patients) male and 28.69% (1328 patients) female patients. Vice versa, in the thorax ward, 71.1% (1200 patients) were female and 28.9% (486 patients) were male patients.Conclusion:There was no any significant difference between male and female hospitalized patients expect 5 clinical wards including gastroenterology, thoracic surgery, orthopedics, trauma and urology. It seems that gender is in a direct association with these 5 disease type. This matter should be considered by policy makers and stakeholders.
92: NECESSITY FOR DEVELOPMENT OF A COMPREHENSIVE MODEL FOR MEASURING E-HEALTH LITERACY
Authors: Kalankesh Leila Ranandeh , Khara Rouhallah 
Published: May 2024

Background and aims:E-Health is considered as a new tool and approach for improving public health. However existence of the health digital divide among different groups of population can act as an obstacle for achieving its goals. Improving the e-Health literacy helps to reduce this gap. Prior to taking any action toward increasing e-health literacy, a comprehensive tool should be created and standardized for measuring it at national level. The aim of this study was to highlight the necessity of developing such a tool and to determine its dimensions.Methods:This study was conducted through systematic review. Search was carried out in WOS, PubMed, Scopus, ProQuest databases through deploying keywords such as “scale”, “model instrument”, “health literacy”, “e-health literacy”, “tool”, “measure”, “questionnaire”, “Necessity” from 2000 to 2015. Information was extracted from papers using qualitative content analysis.Results:40 Paper was included for the final review in this study. The results showed lack of comprehensive and standardized tools to measure e-health literacy. Variety of existing e-health literacy definitions and structures seems to lead researchers toward designing different tools with distinct dimensions for measurement of e-health literacy. Comparative analysis of various aspects of existing tools revealed their similarities, differences and defects. Accordingly it is required to develop a comprehensive tool considering capabilities of existing tools, resolving their weaknesses and removing their defects.Conclusion:Comprehensive electronic health literacy tool is crucial to accurately determine health digital divide in the society. Development of such a tool is the first step toward promoting electronic health literacy and realizing electronics health goals.
93: NEW HORIZON IN THE TREATMENT OF SEPSIS: A SYSTEMATIC REVIEW OF ALTERNATIVE MEDICINE
Authors: Mousavi Sarah , Mirzaie Mahmoud 
Published: May 2024

Background and aims:Despite great advancement in treatment of sepsis, mortality of sepsis remains unacceptably high, even with the modern antibiotic and intensive care technologies. Considering the key role of immune dysfunction in sepsis pathophysiology, different treatments were evaluated, but failed to improve survival of patients. Natural remedies have been tested in various studies to overcome sepsis. In this study, we aim to review some of the evidence from clinical, In vitro and In vivo studies about the effect of alternative medicine on sepsis management.Methods:The following databases were searched up to March 2014: PubMed, Scopus, Web of Science, Ovid and Google Scholar using combination of Mesh term. All in vitro and In Vivo studies also clinical trials published in English which evaluated alternative medicine in management of sepsis were included.Results:Out of 95 relevant studies, the inclusion criteria were met for 78 cases. Among them 18 studies were performed on humans. The most herbal medicine includingXubijing(N=10), and thenRhubarb(n=3). Most of the reviewed botanical medicines modulate immune system. Reduction of mortality also reported in studies.Conclusion:Modulation of immune system, anti-inflammatory activities and improvement of survival were the action of herbal medicine. A monovalent approach is not enough for treatment of sepsis, we recommend further studies to identifies active component of herbal and use them in combination. Also animal model of sepsis does not exactly mimic human sepsis, so more clinical studies should be performed. With no new drug on the horizon, herbal medicine will be promising for treatment of sepsis.
94: ONLINE MANAGEMENT OF METABOLIC SYNDROME AND CARDIOVASCULAR RISK FACTORS: A SIMPLE METHOD FOR AWARENESS AND ACTIONS
Authors: Jahangiry Leila , Farhangi Abbasaliza , Najafi Mahdi 
Published: May 2024

Background and aims:Metabolic syndrome is a major public health problem in worldwide and Iran. It is argued that metabolic syndrome is the most responsible risk factor for developing the disease People with metabolic syndrome has 1.5- to 3-fold increase in the risk of coronary heart disease and stroke. The prevalence of metabolic syndrome in Iran is very high. Consistent with the Adult Treatment Panel III (ATP III), diagnostic criteria for metabolic syndrome include: Abdominal obesity determined by increased waist circumference, raised triglycerides, reduced HDL, elevated blood pressure, and raised plasma glucose. When 3 of 5 of the characteristics are present, a diagnosis of metabolic syndrome can be made. The internet is a relatively new and effective method of delivering strategies to detecting high risk people with metabolic syndrome and helps them adopt healthy behavior. The aim of study is delivering an online interactive method for metabolic syndrome detection among general population in Tehran.Methods:The study web page (http://www.Heartresearch.ir) is designed in order to increase awareness of visitors about prevention of cardiovascular diseases and metabolic syndrome risk factors. Metabolic syndrome components are designed and implement on the study Homepage as interactive calculator tool. Users could use the calculator tool then receive their own risk signs and feedback about each risk factor for metabolic syndrome that they have. Participants were invited for clinical assessments of metabolic syndrome in Tehran Heart Center.Results:In total, 1,437 individuals registered on the study website. Of these, 815 records were excluded because registrants were living outside Tehran (n=356), had a waist circumference <90 cm (n=392), or had incomplete information (no telephone number; n= 67). In total, 317 individuals were invited to clinical assessments. Of these, 229 were able to attend clinical assessments and were scheduled for a baseline visit, finally 171 had metabolic syndrome.Conclusion:Effective and affordable strategies to control the syndrome could benefit the at risk population. The integration of interactive e-health programs to primary health care practices such as prevention of cardiovascular risk factors offers possibilities for on- time interaction with the target group. The use of web-based approaches is a great interest in the management of patients at high cardiovascular risk, especially in a scenario where the prevalence of obesity, metabolic syndrome and diabetes is increasing.
98: PREPARATION, CHARACTERIZATION AND IN VITRO BIOLOGY STUDY OFSATUREJA KHUZESTANICA JAMZADESSENTIAL OIL-LOADED CHITOSAN NANOPARTICLES
Authors: Rashidipour Marzieh 
Published: May 2024

Background and aims:Complimentary medicine plant an important role in treatment of disease because of variety of usefulness.Satureja khuzestanica Jamzadis one of the plants which is used to make nanoparticles.this study aims in Preparation, characterization and in vitro biology study ofSatureja khuzestanica Jamzadessential oil-loaded chitosan nanoparticles.Method:The fabrication ofSatureja khuzestanica Jamzaessential oil (SKE) -loaded chitosan nanoparticles was achieved by a two-step method: oil-in water emulsion and ionic gelation of chitosan with pentasodium tripolyphosphate.Results:The obtained particles possessed encapsulation efficiency (EE) and loading capacity (LC) in the ranges of 13–30% and 3–11.2%, respectively, when the initial carvacrol content was 1–2% of chitosan. The individual particles exhibited a spherical shape with an average diameter of 185.5 nm, and a positively charged surface with a zeta potential value of −24.3 mV. The increment of initial carvacrol content caused a reduction of surface charge. SKE-loaded chitosan nanoparticles showed antimicrobial activity against S. aureus,S. epidermidisandS. agalactiae, E. faecalis,L. monocytogenes, E. coli, S. typhi,S. paratyphi,S. enterica, with an MIC of 62.5, 15.6, 125, 15.6, 7.8, 62.5, 7.8, 15.6, 500 µg/mL, respectively. Skin inflammation was induced in the right hind paw of rats by the topical application of 2 mg/paw of carrageenan dissolved in 0.2 ml of 0.9% saline solution. The anti-inflammatory effect of the SKE-loaded chitosan nanoparticles (25, 50,100 mg/kg) were compared to diclofenac sodium (200mg/kg). SKE-loaded chitosan nanoparticles (50 mg/kg) produced significant anti-inflammatory effect (P<0.01).Conclusion:The findings from our present study suggest that SKE-loaded chitosan nanoparticles anti-inflammatory and antibacterial properties. SKE-loaded chitosan nanoparticles could serve a potential novel compounds effective in inflammatory and antibacterial conditions.
10 ’Thinking about you and your loved one’: session developed to support mnd carers in wales as part of the marie curie caring for carers initiative in wales
Authors: Court Susan S 
Published: May 2024

IntroductionSessions were designed around the practical information and emotional support needs of carers looking after relatives or friends living with MND.More than half (56%) of MND carers spend more than 100 hours every week on their caring role.1Aim and methodTo provide tailored support, information and advice, leading to clear improvements in well-being for carers.Our approach was to provide a safe, supportive environment to enable carers to learn and develop useful coping strategies for their futures.Experienced facilitation allowed conversations the space to emerge and voices to be heard. Attention was focused on a need to pace the flow of information to the responses and individual carer inputs as well as emerging dialogue from group discussions.Results45 carers attended sessions in 2015, 2016 and 2017.• 80% of carers reported a large improvement in their ability to cope with carin with reduced levels of anxiety• 65% of carers reported some improvement in their levels of isolation and overall health• 95% of carers reported a positive change in their level of confidence as a carer• 75% of carers reported a positive change in their knowledge in what improves the wellbeing of the cared for.• 100% of carers reported that they would beExtremely LikelyorLikelyto recommend sessions to friends and family members in a similar position.ConclusionWe were interested in whether, having participated in sessions, there had been any change in carer’s confidence, knowledge or understanding of the various issues surrounding caring for a loved one.Evidence supported significant positive change.Reference. Fitzgerald S.Experiences and views of carers of people living with MND - Findings of the MND Association Carers Survey2015.
16 The significance of intimate relationships at end of life: experiences of young adults with life-limiting or life-threatening conditions
Authors: Earle Sarah , Blackburn Maddie , Cooke Alison 
Published: May 2024

IntroductionUntil relatively recently, children and young people with life-limiting and/or life-threatening conditions (LLTCs) were not expected to live into adulthood. Today there are approximately 55 000 people with a LLTC living in the UK (Norman & Fraser 2014). Given its demographic infancy, very little empirical work has been carried out with this population and even less is known about the needs and expectations of young people with LLTCs on sex and relationships.AimThe project aimed to explore the significance of intimate relationships for young adults with LLTCs focusing, in particular, on the impact of this on their sense of wellbeing.MethodThe study was carried out within a qualitative framework. Twelve participants were recruited to the project via a network of hospices and organisations that support young adults with LLTCs in England. Three focus groups were held in April 2017. The focus groups were hosted by two hospices and one organisation that provide support to young people with LLTCs.ResultsA thematic analysis of the focus group data highlighted three themes relating to the significance of intimate relationships for young adults with LLTCs. These are: (1) intimate relationships as rite of passage; (2) the significance of intimate relationships on happiness and wellbeing, and (3) social isolation and participatory barriers.ConclusionYoung adults with LLTCs experience a combination of social exclusion and social isolation which impacts on their participatory opportunities. This lack of participatory opportunity subsequently impedes their ability to form meaningful, intimate relationships that could contribute to happiness and enhance wellbeing.Reference. Norman P, Fraser L. Prevalence of life-limiting conditions in children and young people in England: Time trends by area type. Health and Place2014;26:171–179. DOI: 10.1016/j.healthplace.2014.01.002.
20 Implementation of music therapy in an inpatient hospice setting: a realist evaluation
Authors: Graham-Wisener Lisa , McConnell Tracey , Porter Sam , Kirkwood Jenny , Clarke Mike , Regan Joan , McKeown Miriam , McGrillen Kerry , Hughes Naomi , Reid Joanne 
Published: May 2024

IntroductionMusic therapy is becoming increasingly common as an adjunct therapy to support symptom management in palliative care settings. There is a small but promising research body identifying the effect of music therapy on patient reported outcomes, including health related quality of life. However, studies to date have paid little attention to the processes which lead to these changes in patient outcomes.AimsTo explore the processes involved in the implementation of music therapy as part of a feasibility randomised control trial to an inpatient specialist palliative care setting in the United Kingdom.MethodsA realist evaluation approach was used. A mixed-methods qualitative approach involved three focus groups with a range of healthcare professionals (n=19) and a music therapist in addition to an analysis of open-text in a quality of life questionnaire with patients (n=11).ResultsMusic therapy contains multiple mechanisms that can provide physical, psychological, emotional, expressive, existential and social support. There is also evidence that the hospice context, instilled by a holistic approach to health care, is an important facilitator of the effects of music therapy. Examination of patients’ responses helped identify specific benefits for patients with particular characteristics.ConclusionsThere is a synergy between the therapeutic aims of music therapy and those of palliative care, which appealed to a significant proportion of participants, who perceived it as effective.
36 Together to care
Authors: Reed Elizabeth , Berg Jane , Spencer Lesley 
Published: May 2024

IntroductionAlthough many care homes are committed to providing good quality end of life care, in reality a significant number of Nursing Home (NH) residents die in hospital after emergency admission hours or days before their death.To provide more coordinated services for dying people and their families, the hospice in partnership with a NH developed a six month project with the NH providing 2 palliative care beds and in return for a comprehensive training package in end of life care.Research aimAssess the impact of the educational intervention on NH staff and therefore their confidence and competence in caring for residents at the end of life.MethodsA longitudinal mixed method approach using 3 methods at baseline, 3 and 6 months:1. A survey to all NH staff incorporating a self-efficacy palliative care scale (SEPC) to rate confidence on a 10 point Likert scale (Mason and Ellershaw, 2004).2. Pre and post intervention semi-structured interviews with the staff participating in the T2C educational intervention.3. Focus group of hospice staff 6 months post T2C educational intervention.ResultsAt 6 months confidence increased and was sustained in all aspects of end of life care but most markedly in communication and symptom control. Confidence decreased in NH staff not undertaking the education intervention indicating work to do in peer learning.ConclusionA palliative care educational intervention can increase confidence and competence in NH staff to care for residents in a NH so reduce risk of unplanned hospital admission.Reference. Mason, S. Ellershaw, J. Assessing undergraduate palliative care education: validity and reliability of two scales examining perceived efficacy and outcome expectancies in palliative care. Medical Education2004;38:1103–1110
39 A qualitative study of family carer’s attitudes towards agitation in people with moderate/severe dementia
Authors: Stringer Aisling , Pritty Elizabeth , Laybourne Anne , Frenais Francesca La , Higgins Shanlee , Doyle Mary-Jo , Leavey Gerry , Livingston Gill , Sampson Elizabeth 
Published: May 2024

BackgroundPeople with severe dementia are often cared for at the end of life in nursing homes or acute hospital wards. In these circumstances, symptoms of agitation such as shouting, aggression, and restlessness are common. Agitation is distressing for the person with dementia and paid and family carers, and it is associated with poorer quality of life. Little is known about the attitudes that family carers have towards agitation in severe dementia. Such attitudes are important because they contribute to the personhood and quality of life of the person living with dementia.AimsTo develop knowledge of the attitudes, explanatory models, and coping strategies of family carers around agitation in people with dementia receiving end of life care in hospitals or nursing homes.MethodsAcross two acute hospital and two nursing home sites, we conducted semi-structured interviews with eight family carers of people with a clinical dementia rating of 2 or 3 (moderate/severe). Interview transcripts were open coded by two researchers. Using an iterative process, our open coding was developed into key themes related to explanatory models and coping strategies.ResultsPreliminary analysis showed that agitation was often attributed to disease pathology rather than the individual. Coping strategies included limiting visits to times when the person with dementia was unlikely to be agitated.ConclusionFamily carers see agitation in people with severe dementia at the end of life as a part of their illness and separate to their personal identity. This functioned as a means of preserving the individual’s personhood.