bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polygenic risk-stratified screening for nasopharyngeal carcinoma in high-risk endemic areas of China: a cost-effectiveness study
Authors: Yang Da-Wei , Miller Jacob A. , Xue Wen-Qiong , Tang Minzhong , Lei Lin , Zheng Yuming , Diao Hua , Wang Tong-Min , Liao Ying , Wu Yan-Xia , Zheng Xiao-Hui , Zhou Ting , Li Xi-Zhao , Zhang Pei-Fen , Chen Xue-Yin , Yu Xia , Li Fugui , Ji Mingfang , Sun Ying , He Yong-Qiao , Jia Wei-Hua 
Published: May 2024

BackgroundNasopharyngeal carcinoma (NPC) has an extremely high incidence rate in Southern China, resulting in a severe disease burden for the local population. Current EBV serologic screening is limited by false positives, and there is opportunity to integrate polygenic risk scores for personalized screening which may enhance cost-effectiveness and resource utilization.MethodsA Markov model was developed based on epidemiological and genetic data specific to endemic areas of China, and further compared polygenic risk-stratified screening [subjects with a 10-year absolute risk (AR) greater than a threshold risk underwent EBV serological screening] to age-based screening (EBV serological screening for all subjects). For each initial screening age (30–34, 35–39, 40–44, 45–49, 50–54, 55–59, 60–64, and 65–69 years), a modeled cohort of 100,000 participants was screened until age 69, and then followed until age 79.ResultsAmong subjects aged 30 to 54 years, polygenic risk-stratified screening strategies were more cost-effective than age-based screening strategies, and almost comprised the cost-effectiveness efficiency frontier. For men, screening strategies with a 1-year frequency and a 10-year absolute risk (AR) threshold of 0.7% or higher were cost-effective, with an incremental cost-effectiveness ratio (ICER) below the willingness to pay (¥203,810, twice the local per capita GDP). Specifically, the strategies with a 10-year AR threshold of 0.7% or 0.8% are the most cost-effective strategies, with an ICER ranging from ¥159,752 to ¥201,738 compared to lower-cost non-dominated strategies on the cost-effectiveness frontiers. The optimal strategies have a higher probability (29.4–35.8%) of being cost-effective compared to other strategies on the frontier. Additionally, they reduce the need for nasopharyngoscopies by 5.1–27.7% compared to optimal age-based strategies. Likewise, for women aged 30–54 years, the optimal strategy with a 0.3% threshold showed similar results. Among subjects aged 55 to 69 years, age-based screening strategies were more cost-effective for men, while no screening may be preferred for women.ConclusionOur economic evaluation found that the polygenic risk-stratified screening could improve the cost-effectiveness among individuals aged 30–54, providing valuable guidance for NPC prevention and control policies in endemic areas of China.
“Let’s get back to normal”: emotions mediate the effects of persuasive messages on willingness to vaccinate for COVID-19
Authors: Muis Krista R. , Kendeou Panayiota , Kohatsu Martina , Wang Shuting 
Published: May 2024

ObjectiveWe examined the effectiveness of three different messages for persuading individuals to get vaccinated against COVID-19, and the role that emotions play in persuasion.MethodsFour hundred-thirty-six participants reported their concern about the COVID-19 pandemic and confidence/hesitancy toward vaccines. Participants were randomly assigned to one of three text conditions: (1) self-interest: a persuasive message that focused on how much of a “serious threat COVID-19 is to you,” and to get vaccinated to “protect yourself”; (2) self-interest + altruistic: a persuasive message that focused on the “threat to you and your community” and to get vaccinated to “protect you and your loved ones”; (3) self-interest + altruistic + normal: a persuasive message that included (2) but added “This is the only way we can get back to a normal life.”; and, (4) a baseline control: no text. After reading, participants reported their emotions toward COVID-19 vaccines and their willingness to get vaccinated.ResultsIndividuals in the self-interest + altruistic + normal condition were more willing to get vaccinated compared to the control condition and self-interest + altruistic condition. However, there were no differences in willingness between the self-interest + altruistic + normal condition and the self-interest condition. Moreover, emotions mediated relations between vaccine confidence/hesitancy and willingness.ConclusionA message that focuses on “getting back to normal” can achieve important public health action by increasing vaccine uptake to protect the population. Future work is needed across multiple countries and contexts (i.e., non-pandemic) to assess message effectiveness.
Surface-modified PVDF membranes for separation of dye by forward osmosis
Authors: Muratow Marta , Yalcinkaya Fatma , Bryjak Marek , Siekierka Anna 
Published: May 2024

Modification of membranes is widely used for altering their separation properties. In this study, the modification of PVDF nanofiber mat by deposition of polyamide layers was evaluated to improve dye recovery by means of forward osmosis process. The polyamide active layer was prepared by a reaction of cyclic aromatic amines, m-phenylenediamine, or piperazine, and trimesoylchloride. The modification progress was monitored by FTIR analysis, water uptake, nitrogen content, and grafting yields. Investigated membranes showed an excellent dye separation features with water flux and dye fluxes strongly related to type of applied amines and reaction time. The best obtained membrane demonstrated outstanding performance in forward osmosis; their water flux was 3.3 LMH and rejection rate of 97% for bromocresol green dye. The membrane allowed increase dye concentration by 50% after 24 h of the process.
Development of a large animal orthotopic intestinal transplantation model with long-term survival for study of immunologic outcomes
Authors: Merl Sarah , Chen Bryan , Gunes M. Esad , Atta Hussein , Yang Kryscilla , Ekanayake-Alper Dilrukshi , Hajosi Dominik , Huang Fei , Bhola Brittany , Patwardhan Satyajit , Jordache Philip , Nowak Greg , Martinez Mercedes , Kato Tomoaki , Sykes Megan , Yamada Kazuhiko , Weiner Joshua 
Published: May 2024

IntroductionIntestinal transplantation (ITx) is the last remaining therapy for patients with intestinal failure once parenteral nutrition is no longer an option, however its use is limited by immunological complications, including high rates of rejection and morbidity associated with immunosuppression, such as infection and malignancy. We aimed to develop a large animal model of ITx with which to study the immune response to ITx and to design and test tolerance induction regimens.MethodsLearning from prior complications, we developed and progressively improved both surgical methods for the donor and recipient as well as postoperative management strategies. Methods of stoma generation, bowel positioning, vessel preparation, and fluid management were optimized. The immunosuppression strategy mirrored our clinical regimen.ResultsAs a result of our modifications, results improved from survival less than 1 month to consistent long-term survival with good graft function. We review several techniques that were developed to avoid pitfalls that were encountered, which can be used to optimize outcomes in this model.DiscussionAchieving long-term survival after swine orthotopic ITx permits immunological analysis and pre-clinical trials in a large animal model of ITx.
Basic psychological need satisfaction of collegiate athletes: the unique and interactive effects of team identification and LMX quality
Authors: Leduc Joé G. , Boucher Frédéric , Marques Dominic L. , Brunelle Eric 
Published: May 2024

PurposeThe present study sought to understand the relationships between team identification, leader-member exchange (LMX) quality, and the basic psychological need satisfaction of collegiate athletes, as well as the moderating role of coach-athlete LMX quality.MethodsSelf-reported data from 319 collegiate athletes were analyzed using SPSS version 29. The relationships between the study variables were tested by moderation analysis using PROCESS macro model 1.ResultsRegression analyses showed team identification to be positively related to the satisfaction of the needs for competence and relatedness, while LMX quality was positively related to the satisfaction of the needs for competence and autonomy. Furthermore, moderation analyses showed that LMX quality positively moderated the relationship between team identification and the satisfaction of the needs for competence and relatedness.ConclusionThe results of this study highlight the important role that team identification and LMX quality play in the satisfaction of the basic psychological needs of collegiate athletes. The implications of these results for the optimal functioning of collegiate athletes are discussed.
Urinary angiotensin-converting enzyme 2 and its activity in cats with chronic kidney disease
Authors: Kuo Tzu-Chien , Hsu Wei-Li , Wu Vin-Cent , Jan Tong-Rong , Tsai Pei-Shiue Jason , Lee Ya-Jane 
Published: May 2024

IntroductionAngiotensin-converting enzyme 2 (ACE2) played an important role in the renin-angiotensin-aldosterone system (RAAS) and it was proved to be renoprotective in renal disease. Urinary angiotensin-converting enzyme 2 (uACE2) has been shown to reflect renal injury in human and experimental studies, but its role in feline kidney disease remains unknown.AimsOur objectives involve comparing uACE2 concentrations and activities in cats across CKD stages with healthy controls, investigating the relationship between uACE2 concentrations, activities, and clinicopathological data in feline CKD patients, and assessing the predictive abilities of both for CKD progression.MethodsA retrospective, case–control study. The concentration and activity of uACE2 were measured by commercial ELISA and fluorometric assay kits, respectively. The concentration was adjusted to give uACE2 concentration-to-creatinine ratios (UACCRs).ResultsIn total, 67 cats consisting of 24 control and 43 chronic kidney disease (CKD), including 24 early-stage CKD and 19 late-stage CKD, were enrolled in this study. UACCR values were significantly higher in both early-stage (2.100 [1.142–4.242] x 10−6) and late-stage feline CKD (4.343 [2.992–5.0.71] x 10−6) compared to healthy controls (0.894 [0.610–1.076] x 10−6; p &lt; 0.001), and there was also significant difference between-early stage group and late-stage group (p = 0.026). Urinary ACE2 activity (UAA) was significantly lower in CKD cats (1.338 [0.644–2.755] x pmol/min/ml) compared to the healthy cats (7.989 [3.711–15.903] x pmol/min/ml; p &lt; 0.001). UACCR demonstrated an independent, positive correlation with BUN (p &lt; 0.001), and UAA exhibited an independent, negative correlation with plasma creatinine (p &lt; 0.001). Both UACCR and UAA did not yield significant results in predicting CKD progression based on the ROC curve analysis.Conclusion and clinical importanceuACE2 concentration and activity exhibit varying changes as renal function declines, particularly in advanced CKD cats.
THIẾT KẾ CHẾ TẠO VÀ SỬ DỤNG BỘ THÍ NGHIỆM KHẢO SÁT HỢP LỰC ĐỒNG QUY NHẰM PHÁT TRIỂN NĂNG LỰC GIẢI QUYẾT VẤN ĐỀ VÀ SÁNG TẠO CỦA HỌC SINH TRONG DẠY HỌC VẬT LÝ Ở TRƯỜNG PHỔ THÔNG
Authors: Trung Nghiêm Hồng 
Published: May 2024

Học sinh gặp khó khăn và nhầm lẫn khi học về hợp lực đồng quy; với thiết bị thí nghiệm hiện hành chưa có phương án thể hiện được đầy đủ quy tắc hợp lực đồng quy và người thầy gặp khó khăn khi dùng nó để tổ chức hoạt động nhận thức dạy học nhằm phát triển năng lực giải quyết vấn đề, năng lực sáng tạo của học sinh; tác giả nhận thấy cần phải chế tạo một bộ thí nghiệm mới. Từ những khảo sát việc sử dụng bộ thí nghiệm hiện hành trong dạy học ở một số trường học khác nhau, tác giả đã nghiên cứu những hạn chế và nhược điểm của bộ thí nghiệm hiện hành. Đồng thời, nghiên cứu đã chế tạo ra thiết bị mới giải quyết được những hạn chế nêu trên, kết quả thực hiện với bộ thí nghiệm mới cho độ chính xác rất cao, phát triển được năng lực giải quyết vấn đề, năng lực sáng tạo của học sinh.
Clinical Aspects of Newborn's Haemodynamics in the Neonatal Period
Authors: Белкин А.М. , Кизатова С.Т. , Устинович Ю.А. 
Published: May 2024

Наиболее значительная и радикальная адаптация человека к изменениям условий жизни происходит за время первых вдохов, когда плод переходит из внутриутробной во внеутробную среду с существенной перестройкой гемодинамики. При доношенном сроке беременности успешный постнатальный переход осуществляется за счет снижения легочного сосудистого сопротивления после раскрытия легких, повышения системного сосудистого сопротивления в результате пережатия плаценты и последующего закрытия фетальных коммуникаций. Перенаправление кровотока, воздействие повышенного парциального давления кислорода в крови и нейроэндокринный всплеск способствуют значительному перераспределению системного и органного кровотока для удовлетворения метаболических и функциональных потребностей внеутробной жизни. У недоношенного ребенка на нормальный физиологический переход влияют несколько факторов, включая, в частности, незрелость систем органов, состояние матери и принимаемые ею препараты, время пережатия пуповины и реанимационные маневры. Понимание этого сложного процесса имеет решающее значение для выхаживания недоношенных новорожденных, особенно в условиях неонатальной интенсивной терапии.
The most significant and radical human adaptation to changes in living conditions occurs during the first breaths, when the foetus transitions from the intrauterine to the extrauterine environment with a significant restructuring of haemodynamics. In premature gestation, successful postnatal transition is due to a decrease in pulmonary-vascular resistance after lung opening, an increase in systemic vascular resistance as a result of placental constriction and subsequent closure of fetal communications. Redirection of blood flow, exposure to increased partial pressure of oxygen in the blood and neuroendocrine surge contribute to a significant redistribution of systemic and organ blood flow to meet the metabolic and functional needs of extrauterine life. In the preterm infant, several factors affect the normal physiological transition, including immaturity of organ systems, maternal condition and medications, timing of cord clamping and resuscitative manoeuvres, among others. Understanding this complex process is critical for nursing premature neonates, especially in the neonatal intensive care setting.
KONTRIBUSI USAHA BUDIDAYA IKAN KUWE DENGAN KERAMBA JARING APUNG TERHADAP PENDAPATAN KELUARGA DI KELURAHAN SINDULANG I KECAMATAN TUMINTING KOTA MANADO
Authors: Kulangke Jeksen Tiago Wahyu , Andaki Jardie A. , Pangemanan Jeannette F. , Aling Djuwita R.R. , Dien Christian R. , Tambani Grace O. 
Published: May 2024

Abstract
The aim of this research is to find out how much income trevally fish farmers earn and how much contribution the results of the trevally fish farming business make to the income of fishing families in Sindulang I Village.
The research method used in this research is a survey. The population in this study are fishermen who work as pompano fish farmers. Data collection was carried out by sampling. Sampling was carried out by purposive sampling. The data collected consists of primary data and secondary data. Primary data collection in this research was carried out through observation and interviews guided by a questionnaire. Secondary data was obtained from agencies related to research. The data obtained was analyzed using quantitative descriptive analysis and qualitative descriptive analysis.
Based on the research results, the following results were obtained: 1) the income of fishing families from the trevally fish cultivation business using floating net cages is IDR 74,000,000 per year; 2) opinion outside the cultivation business Rp. 51,000,000; and 3) the contribution of the pompano fish cultivation business to family income is 59.20%.
Key words: cultivator; giant trevally; profit; contribution

Abstrak
Tujuan penelitian ini ialah mengetahui berapa besar pendapatan pembudidaya ikan kuwe dan seberapa besar kontribusi hasil usaha budidaya ikan kuwe terhadap pendapatan keluarga nelayan yang ada di Kelurahan Sindulang I.
Metode penelitian yang digunakan dalam penelitian ini yaitu survei. Populasi dalam penelitian ini ialah nelayan yang berprofesi sebagai pembudidaya ikan kuwe. Pengambilan data dilakukan secara sampling. Pengambilan sampel dilakukan dengan cara purposive sampling. Data yang dikumpulkan terdiri dari data primer dan data sekunder. Pengumpulan data primer dalam penelitian ini dilakukan melalui observasi dan wawancara yang dipandu dengan kuesioner. Data sekunder diperoleh dari instansi yang berkaitan dengan penelitian. Data yang diperoleh dianalisis dengan analisis diskriptif kuantitatif dan diskriptif kualitatif.
Berdasarkan hasil penelitian didapat hasil sebagai berikut: 1) pendapatan keluarga nelayan dari usaha budidaya ikan kuwe dengan keramba jaring apung yaitu Rp74.000.000 per tahun; 2) pendapat di luar usaha budidaya Rp51.000.000; dan 3) kontribusi usaha budidaya ikan kuwe terhadap pendapatan keluarga 59,20%.
Kata kunci: pembudidaya; ikan kuwe; keuntungan; kontribusi
Complete terahertz absorber: coupled topological like structure, spaced graphene and magneto-optic effect
Authors: J Gulzar Ali , Mohanty Sanjay Kumar , Nayak Chittaranjan 
Published: May 2024

Abstract
The work examines terahertz (THz) broadband absorbers for unit topological structure (UTS) with spaced graphene. This study examined the transmission and absorption of the proposed structure without and with graphene at each dielectric interface. The UTS absorbed more light while using a cascade structure with a structural index (n) and adjusting dielectric thicknesses (Δ). Absorption increased significantly with an external magnetic field (B). The objective for a complete THz absorber is achieved with average absorption,

A

¯

= 0.8093 by a modified structure with n = 5, applying an external magnetic field, B = 10.7 T, Fermi level, E
F = −0.48 eV, and manipulating the thickness parameter Δ.
Tata Kelola Perkotaan dan Ketahanan Ekonomi di Indonesia: Suatu Tinjauan Kualitatif
Authors: Purnama Susan , Reyta Fitriani , Foster Bob , Sinaga Johnson 
Published: May 2024

Masyarakat perkotaan menghadapi berbagai tantangan, salah satunya memperkuat ketahanan perekonomian. Tujuan dari penelitian ini adalah mengungkap hubungan antara ketahanan ekonomi dan tata kelola perkotaan yang baik di Indonesia, khususnya kota Bandung dalam bidang kebijakan penyaluran kredit. Temuan pada penelitian ini dikonseptualisasikan secara deskripsi kualitatif. Berdasarkan temuan yang diperoleh, penerapan good urban governance di bidang program kredit korporasi masih belum optimal dan masih diperlukan pengembangan lebih lanjut pada kebijakan dan pengawasan terhadap petugas penyalur dana, lembaga penyalur dan penerima dukungan keuangan. Masih ada oknum yang menyelewengkan dana. Artinya masih terdapat kesenjangan dalam implementasi dan salah satu prinsip transparansi belum tercapai. Implikasi manajerial bagi pemerintah kota Bandung adalah peningkatan penyaluran kredit ke sektor produktif khususnya sektor jasa, menambahkan agunan sebelum penyaluran kredit, dan peningkatan mitigasi resiko kredit terhadap debitur muda, debitur berpenghasilan menengah (Rp 10 -20 juta/bulan), dan debitur yang dikenai suku bunga yang lebih tinggi.
Meningkatkan Pendapatan Petani melalui Pendampingan Budidaya Pisang Cavendish di Desa Sukadana
Authors: Zuhdiyah Matienatul Iemaaniah  , Dori Kusuma Jaya  , Siska Ita Selvia  , Suprayanti Martia Dewi  , Afifah Farida Jufri  , Dwi Noorma Putri  , Novita Hidayatun Nuvus  , Anjar Pranggawan Azhari  , Amrul Jihadi  , Yuliana Asri  
Published: May 2024

Pengembangan budidaya pisang cavendish memiliki potensi yang lebih tinggi dibandingkan dengan pisang jenis lain. Hal ini dikarenakan pisang cavendish memiliki nilai jual pasar yang lebih tinggi terutama dapat menjadi jenis pisang yang sangat laku dipasar internasional. Salah satu desa yang berpotensi untuk dikembangkan budidaya pohon pisang cavendish adalah Desa Sukadana. Desa ini merupakan salah satu desa penyangga kawasan ekonomi Khusus Mandalika yang diharapkan dapat menyediakan kebutuhan pertanian pokok yang ada di kawasan Mandalika. Kegiatan pengabdian dilaksanakan pada bulan desember tahun 2022 hingga mei 2023 dengan kelompok tani sasaran Patuh Bersama. Kegiatan pengabdian ini bertujuan untuk meningkatkan pendapatan masyarakat melalui pendampingan pembudidayaan pisang cavendish. Hasil kegiatan pengabdian yang dilakukan yaitu memberikan wawasan pada masyarakat bahwa pisang cavedish merupakan jenis pisang yang biasa dikonsumsi Masyarakat internasional, selain itu Masyarakat juga dapat mengembangkan pembudidayaan pisang cavendish tidak hanya dipekarangan, akan tetapi juga dapat membudidayakan dilahan pertanian yang belum termanfaatkan.
Evaluación de un Examen de Admisión a Pregrados: Metodológica de Medidas Repetidas con JASP
Authors: Ponce Renova Héctor Francisco , Jiménez Castañeda Ramses , Ronquillo Chávez Cely Celene 
Published: May 2024

La pregunta fue: ¿Existe una diferencia estadísticamente significativa entre los puntajes promedio de los aspirantes a través de las cinco ocasiones/generaciones? El objetivo fue dual: Analizar puntajes de aspirantes (n = 34,617) a 32 programas de pregrado de una universidad pública Mexicana con el Examen de Habilidades y Conocimientos Básicos con el uso del Análisis de Varianza de Medidas Repetidas; y enseñar como utilizar el Análisis de Varianza de Medidas Repetidas con el uso de JASP. El método consto de recolectar del examen de admisión de cinco generaciones de aspirantes (2016-2018), describir y analizar os datos con Análisis de Varianza de Medidas Repetidas. También, se detalló como se usa JASP para este análisis y como se interpreta la hoja de resultados. Los resultados mostraron que no existe diferencia de los puntajes entre las ocasiones/generaciones (p = .262) con una varianza explicada considerada pequeña (eta cuadrado parcial de .042). En conclusión, aparentemente no existe diferencia entre los puntajes de las cinco ocasiones/generaciones, y no aparecieron indicios de algún efecto. Asimismo, se encontraron correlaciones altas de .79 hasta .93 entre las ocasiones/generaciones. Estos resultados se pueden interpretar como una gran consistencia en aspirar a los mismos pregrados a través del tiempo.
Hubungan Beban Kerja, Pola Makan, Status Gizi terhadap Produktivitas Kerja pada Dokter dan Perawat Di RS XYZ Sumatera Selatan
Authors: Wijayanthi Putu Ratih , Muthohharoh Viera Dzakiyyah , Fitkarani Ory Laras , Bernarto Innocentius 
Published: May 2024

The purpose of the study was to determine the relationship between workload, diet, nutritional status and work stress with work productivity in doctors and nurses of XYZ Hospital in South Sumatra. The research method used is quantitative using Structural Equation Modeling (SEM) Partial Least Square (PLS), using SMART PLS 4.0 Software. The sample used in this study was 159 doctors and nurses. Data collection tools in the form of questionnaires about workload, diet, nutritional status, work stress and work productivity. The results showed that workload, diet, nutritional status had a positive effect on work productivity in doctors and nurses at XYZ Hospital in South Sumatra.