bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stereoselective Hydride Transfer by Aryl‐Alcohol Oxidase, a Member of the GMC Superfamily
Authors: Hernández‐Ortega Aitor , Ferreira Patricia , Merino Pedro , Medina Milagros , Guallar Victor , Martínez Angel T. 
Published: January 2012

AbstractPrimary alcohol oxidation by aryl‐alcohol oxidase (AAO), a flavoenzyme providing H2O2 to ligninolytic peroxidases, is produced by concerted proton and hydride transfers, as shown by substrate and solvent kinetic isotope effects (KIEs). Interestingly, when the reaction was investigated with synthesized (R)‐ and (S)‐α‐deuterated p‐methoxybenzyl alcohol, a primary KIE (≈6) was observed only for the R enantiomer, revealing that the hydride transfer is highly stereoselective. Docking of p‐methoxybenzyl alcohol at the buried crystal active site, together with QM/MM calculations, showed that this stereoselectivity is due to the position of the hydride‐ and proton‐receiving atoms (flavin N5 and His502 Nε, respectively) relative to the alcohol Cα‐substituents, and to the concerted nature of transfer (the pro‐S orientation corresponding to a 6 kcal mol−1 penalty with respect to the pro‐R orientation). The role of His502 is supported by the lower activity (by three orders of magnitude) of the H502A variant. The above stereoselectivity was also observed, although activities were much lower, in AAO reactions with secondary aryl alcohols (over 98 % excess of the R enantiomer after treatment of racemic 1‐(p‐methoxyphenyl)ethanol, as shown by chiral HPLC) and especially with use of the F501A variant. This variant has an enlarged active site that allow better accommodation of the α‐substituents, resulting in higher stereoselectivity (S/R ratios) than is seen with AAO. High enantioselectivity in a member of the GMC oxidoreductase superfamily is reported for the first time, and shows the potential for engineering of AAO for deracemization purposes.
A benchmark spike‐in data set for biomarker identification in metabolomics
Authors: Franceschi Pietro , Masuero Domenico , Vrhovsek Urska , Mattivi Fulvio , Wehrens Ron 
Published: January 2012

The development and the validation of innovative approaches for biomarker selection are of paramount importance in many ‐omics technologies. Unfortunately, the actual testing of new methods on real data is difficult, because in real data sets, one can never be sure about the “true” biomarkers. In this paper, we present a publicly available metabolomic ultra performance liquid chromatography–mass spectrometry spike‐in data set for apples. The data set consists of 10 control samples and three spiked sets of the same size, where naturally occurring compounds are added in different concentrations. In this sense, the data set can serve as a test bed to assess the performance of new algorithms and compare them with previously published results.We illustrate some of the possibilities provided by this spike‐in data set by comparing the performance of two popular biomarker‐selection methods, the univariate t‐test and the multivariate variable importance in projection. To promote a widespread use of the data, raw data files as well as preprocessed peak lists are made available. Copyright © 2012 John Wiley & Sons, Ltd.
Fluorescent Detection of Hypochlorous Acid from Turn‐On to FRET‐Based Ratiometry by a HOCl‐Mediated Cyclization Reaction
Authors: Yuan Lin , Lin Weiying , Xie Yinan , Chen Bin , Song Jizeng 
Published: January 2012

AbstractHypochlorous acid (HOCl), a reactive oxygen species (ROS), plays a significant biological role in living systems. However, abnormal levels of HOCl are implicated in many inflammation‐associated diseases. Therefore, the detection of HOCl is of great importance. In this work, we describe the HOCl‐promoted cyclization of rhodamine‐thiosemicarbazides to rhodamine‐oxadiazoles, which is then exploited as a novel design strategy for the development of a new fluorescence turn‐on HOCl probe 2. On the basis of the fluorescence resonance energy transfer (FRET) signaling mechanism, 2 was further converted into 1 a and 1 b, which represent the first paradigm of FRET‐based ratiometric fluorescent HOCl probes. The outstanding features of 1 a and 1 b include well‐resolved emission peaks, high sensitivity, high selectivity, good functionality at physiological pH, rapid response, low cytotoxicity, and good cell‐membrane permeability. Furthermore, these excellent attributes enable us to demonstrate, for the first time, the ratiometric imaging of endogenously produced HOCl in living cells by using these novel ratiometric probes. We expect that 1 a and 1 b will be useful molecular tools for studies of HOCl biology. In addition, the HOCl‐promoted cyclization reaction of rhodamine‐thiosemicarbazides to rhodamine‐oxadiazoles should be widely applicable for the development of different types of fluorescent HOCl probes.
Visible‐Light‐Induced Selective Photocatalytic Aerobic Oxidation of Amines into Imines on TiO2
Authors: Lang Xianjun , Ma Wanhong , Zhao Yubao , Chen Chuncheng , Ji Hongwei , Zhao Jincai 
Published: January 2012

AbstractImines are important intermediates for the synthesis of fine chemicals, pharmaceuticals, and agricultural chemicals. Selective oxidation of amines into their corresponding imines with dioxygen is one of the most‐fundamental chemical transformations. Herein, we report the oxidation of a series of benzylic amines into their corresponding imines with atmospheric dioxygen as the oxidant on a surface of anatase TiO2 under visible‐light irradiation (λ>420 nm). The visible‐light response of this system was caused by the formation of a surface complex through the adsorption of a benzylic amine onto the surface of TiO2. From the analysis of products of specially designed benzylic amines, we demonstrated that a highly selective oxygenation reaction proceeds via an oxygen‐transfer mechanism to afford the corresponding carbonyl compound, whose further condensation with an amine would generate the final imine product. We found that when primary benzylic amines (13 examples), were chosen as the substrates, moderate to excellent selectivities for the imine products were achieved (ca. 38–94 %) in moderate to excellent conversion rates (ca. 44–95 %). When secondary benzylic amines (15 examples) were chosen as the substrates, both the corresponding imines and aldehydes were detected as the main products with moderate to high conversion rates (ca. 18–100 %) and lower selectivities for the imine products (ca. 14–69 %). When tribenzylamine was chosen as the substrate, imine (27 %), dibenzylamine (24 %), and benzaldehyde products (39 %) were obtained in a conversion of 50 %. This report can be viewed as a prototypical system for the activation of CH bonds adjacent to heteroatoms such as N, O, and S atoms, and oxofuctionalization with air or dioxygen as the terminal oxidant under visible‐light irradiation using TiO2 as the photocatalyst.
ChemInform Abstract: In Search of Chemical Frustration in the Ca—Cu—Cd System: Chemical Pressure Relief in the Crystal Structures of Ca5Cu2Cd and Ca2Cu2Cd9.
Authors: Harris Nicholas A. , Hadler Amelia B. , Fredrickson Daniel C. 
Published: January 2012

AbstractTwo new compounds in the Ca—Cu—Cd system of nominal composition Ca5Cu2Cd and Ca2Cu2Cd9 are synthesized from nearly stoichiometric mixtures of the elements (1100 °C, 48 h).
ChemInform Abstract: Structure, Bonding, and Phase Relations in Bi2Sn2O7 and Bi2Ti2O7 Pyrochlores: New Insights from High Pressure and High Temperature Studies.
Authors: Salamat Ashkan , Hector Andrew L. , McMillan Paul F. , Ritter Clemens 
Published: January 2012

AbstractCompression of Bi2Ti2O7 does not result in any phase changes up to about 33 GPa.
ChemInform Abstract: Synthesis, Crystal Structures and Properties of the Zintl Phases Sr2ZnP2, Sr2ZnAs2, A2ZnSb2 and A2ZnBi2 (A: Sr and Eu).
Authors: Wilson Dereck K. , Saparov Bayrammurad , Bobev Svilen 
Published: January 2012

AbstractThe title compounds are prepared from the elements using Zn, Pb, or Sn as a flux (900—1000 °C, 20 h).
ChemInform Abstract: HfSb2‐xTex: The Second New Compound on the Quasi‐Binary Section HfSb2—HfTe2 with Different Sb—Sb Interactions.
Authors: Kleinke Katja M. , Assoud Abdeljalil , Kleinke Holger 
Published: January 2012

AbstractHfSb2‐xTex (0.4 ≤ x ≤ 0.7) is synthesized from the elements (900 °C, 7 d).
ChemInform Abstract: Hydrothermal Descriptive Chemistry and Single Crystal Structure Determination of Cesium and Rubidium Thorium Fluorides.
Authors: Underwood Christopher C. , Mann Matthew , McMillen Colin D. , Kolis Joseph W. 
Published: January 2012

AbstractThe new compounds (III) and (V)—(VII) are structurally characterized using powder and single crystal XRD.
ChemInform Abstract: Heteroatomic Si/Ge Zintl Clusters: Single‐Crystal Structure Determination of Rb4[Si7.8Ge1.2](NH3)5 and [Rb([18]crown‐6)Rb3] [Si7.5Ge1.5](NH3)4.
Authors: Waibel Markus , Benda Christian B. , Wahl Bernhard , Faessler Thomas F. 
Published: January 2012

AbstractThe ternary Zintl phases K12Si17‐xGex (x = 5, 9, 12) and Rb12Si17‐xGex (x = 1, 5, 9, 12) are prepared from the elements (900 °C, 1 h).
ChemInform Abstract: Hydrothermal Synthesis, Structure Characterization and Catalytic Property of a Zigzag Chain Structural Cluster Compound Built on the Novel Tetra‐Capped and Centered By NiII.
Authors: Yan Dawei , Chen Qi , Xu Yan , Sun Qi , Zhu Dunru , Song You , Elangovan S. P. 
Published: January 2012

AbstractThe novel Mo/W mixed Keggin derivative (IV) is characterized by powder and single crystal XRD, XPS, IR spectroscopy, and magnetic susceptibility measurements.
ChemInform Abstract: Synthesis, Structural Transformation, Thermal Stability, Valence State, and Magnetic and Electronic Properties of PbNiO3 with Perovskite‐ and LiNbO3‐Type Structures.
Authors: Inaguma Yoshiyuki , Tanaka Kie , Tsuchiya Takeshi , Mori Daisuke , Katsumata Tetsuhiro , Ohba Tomonori , Hiraki Ko‐ichi , Takahashi Toshihiro , Saitoh Hiroyuki 
Published: January 2012

AbstractThe high‐pressure perovskite‐type PbNiO3 phase is obtained from a stoichiometric mixture of β‐PbO2 and NiO (3 GPa, 800 °C, 1 ).
ChemInform Abstract: Hydrothermal Synthesis, Crystal Structure and Property of a Barbell‐Like Copper Complex with {(μ‐F)[(μ‐O)2(NbF4)2]} as the Handle Bar.
Authors: Alimaje Kundawlet , Liu Mingguan , Peng Jun , Zhang Pengpeng , Wang Xiang , Zhu Min , Wang Dandan , Meng Cuili 
Published: January 2012

AbstractThe new compound (III) crystallizes in the monoclinic space group C2/c with Z = 4 (single crystal XRD).
ChemInform Abstract: Quaternary Germanide Arsenides ZrCuGeAs and HfCuGeAs.
Authors: Baergen Alyson M. , Blanchard Peter E. R. , Stoyko Stanislav S. , Mar Arthur 
Published: January 2012

AbstractThe title compounds are prepared by reaction of “ZrCuGe” or “HfCuGe” precursors (obtained by arc melting of the elements) with As at 800 °C for two weeks.
ChemInform Abstract: Asymmetric Henry Reaction Catalyzed by a Zn‐Amino Alcohol System.
Authors: Zheng Bing , Wang Min , Li Zhiyuan , Bian Qinghua , Mao Jianyou , Li Shuoning , Liu Shangzhong , Wang Mingan , Zhong Jiangchun , Guo Hongchao 
Published: January 2012

AbstractAromatic as well as aliphatic aldehydes undergo the Henry reaction with nitromethane under catalysis of an in situ generated chiral amino alcohol—Zn complex to give the corresponding β‐nitroalcohols in moderate to good enantioselectivity.
ChemInform Abstract: Chemo‐ and Regioselectivity‐Tunable Pd‐Catalyzed Allylic Alkylation of Imines.
Authors: Chen Jian‐Ping , Peng Qian , Lei Bai‐Lin , Hou Xue‐Long , Wu Yun‐Dong 
Published: January 2012

AbstractThe chemo‐ and regioselectivity in the Pd‐catalyzed allylic alkylation can be tuned by using bases with different counterions.
ChemInform Abstract: Highly Stereoselective Synthesis of Tetrasubstituted Alkenes via Hydroamination of Alkynes and C—H Acetoxylation.
Authors: Liu Weibing , Chen Cui , Zhang Qing 
Published: January 2012

AbstractThe synthesis of tetrasubstituted (E)‐alkenes by hydroamination of alkynes and subsequent diacetoxyiodobenzene mediated acylation and isomerization is described.
ChemInform Abstract: Synthesis of α,β‐Unsaturated γ‐Amino Esters with Unprecedented High (E)‐Stereoselectivity and Their Conformational Analysis in Peptides.
Authors: Mali Sachitanand M. , Bandyopadhyay Anupam , Jadhav Sandip V. , Kumar Mothukuri Ganesh , Gopi Hosahudya N. 
Published: January 2012

AbstractThe synthesis of α,β‐unsaturated γ‐amino esters using Wittig reaction is reported.
ChemInform Abstract: Proline‐Based Reduced Dipeptides as Recyclable and Highly Enantioselective Organocatalysts for Asymmetric Michael Addition.
Authors: Cao Xiaohui , Wang Ge , Zhang Richeng , Wei Yingying , Wang Wei , Sun Huichao , Chen Ligong 
Published: January 2012

AbstractA new family of organocatalysts is prepared and used to promote highly efficient asymmetric Michael addition reactions of ketones and aldehydes to nitroolefins.
ChemInform Abstract: Coupling of ortho‐Substituted Aryl Chlorides with Bulky Amides.
Authors: Falk Florian C. , Froehlich Roland , Paradies Jan 
Published: January 2012

AbstractVoluminous amides such as (II) and (VIII) are coupled with deactivated, sterically hindered aryl chlorides (I), (IV) and (VII) in high yields providing products (III), (VI) and (IX) which are not efficiently accessible by transition metal catalysis so far.
ChemInform Abstract: Nitropyridines. Part 11. Recyclization of Quaternary Nitropyridinium Salts into Substituted Nitroanilines.
Authors: Garkushenko A. K. , Poendaev N. V. , Vorontsova M. A. , Sagitullina G. P. 
Published: January 2012

AbstractThe synthesis of nitronilines by recyclization of nitropyridinium salts is studied and the differences in the behavior of 3‐, 5‐, and 4‐nitropyridinium compounds are discussed.
ChemInform Abstract: Synthesis of α,α‐Disubstituted Aryl Amines by Rhodium‐Catalyzed Amination of Tertiary Allylic Trichloroacetimidates.
Authors: Arnold Jeffrey S. , Cizio Gregory T. , Nguyen Hien M. 
Published: January 2012

AbstractThe formation of the desired products is accompanied by little or trace amounts of linear amines such as (IV).
ChemInform Abstract: Iridium Diamine Catalyst for the Asymmetric Transfer Hydrogenation of Ketones.
Authors: Vazquez‐Villa Henar , Reber Stefan , Ariger Martin A. , Carreira Erick M. 
Published: January 2012

AbstractA chiral aqua iridium(III) diamine complex is used in the asymmetric transfer hydrogenation of various α‐cyano and α‐nitro ketones to afford the corresponding optically active alcohols with high enantioselectivities.
ChemInform Abstract: Asymmetric Induction by (S)‐4‐Isopropyl‐1‐phenylimidazolidin‐2‐thione in Titanium‐Mediated Aldol Reactions and Its Application in Enantioselective Synthesis of (R)‐Baclofen.
Authors: Khatik Gopal L. , Khurana Ravi , Kumar Varun , Nair Vipin A. 
Published: January 2012

AbstractThe efficiency of the chiral auxiliary is investigated and the utility of the method is demonstrated by the synthesis of (R)‐baclofen (X).
ChemInform Abstract: Diazaphospholane as an Efficient Ligand for Copper‐Catalyzed Cross‐Coupling of Thiols with Aryl Iodides.
Authors: Yang Minghua , Pei Ji , Yan Guobing , Zheng Yunfa 
Published: January 2012

AbstractThe use of an air‐stable diazaphospholane as ligand for the copper‐catalyzed coupling of aryl iodides with thiols is described.
ChemInform Abstract: Efficient Copper‐Induced Coupling Between NH‐Fluoroalkylated Sulfoximines and Aryl Iodides or Bromides.
Authors: Mace Yohan , Pegot Bruce , Guillot Regis , Bournaud Chloee , Toffano Martial , Vo‐Thanh Giang , Magnier Emmanuel 
Published: January 2012

AbstractAn efficient synthesis of fluorinated N‐aryl sulfoximines (III) and (VI) is presented, involving the copper‐catalyzed N‐arylation of the corresponding sulfoximines (I) and (IV), resp., with aryl iodides or bromides.
ChemInform Abstract: Hydroamination/‐amidation of 1,3‐Diynes with Indoles/Azoles/Amides under Modified Ullmann Conditions: Stereo‐ and Regioselective Synthesis of N‐Alkenynes via N—H Bond Activation.
Authors: Gupta Sahaj , Agarwal Piyush K. , Saifuddin Mohammad , Kundu Bijoy 
Published: January 2012

AbstractReaction of diynes (II) and (XII) with indoles and azoles proceeds regioselectively to form mixtures of the title compounds.
ChemInform Abstract: Waste‐Free Catalytic Propargylation/Allenylation of Aryl and Heteroaryl Nucleophiles and Synthesis of Naphthopyrans.
Authors: McCubbin J. Adam , Nassar Costa , Krokhin Oleg V. 
Published: January 2012

AbstractThe reaction of electron‐rich heterocycles and electron‐rich arenes is examined with different di‐ and trisubstituted propargylic alcohols.
ChemInform Abstract: The [2 + 2] Cycloaddition Reaction of Ethynylated 2H‐Cyclohepta[b]furan‐2‐ones with 2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone.
Authors: Shoji Taku , Higashi Junya , Ito Shunji , Yasunami Masafumi , Morita Noboru 
Published: January 2012

AbstractEthynylated heteroazulenes (II) react with DDQ (I) in a formal [2+2]cycloaddition reaction to provide the stable DDQ adducts(III) in good yields, although some electron‐rich arene‐substituted substrates do not afford the presumed cycloaddition products.
ChemInform Abstract: Systematic Synthesis and Characterization of a Series of Tetra(5‐aryl‐2‐thienyl)thiophenes.
Authors: Muraoka Hiroki , Tanifuji Takanori , Ogawa Satoshi 
Published: January 2012

AbstractAryl‐functionalized tetrathienylthiophenes (IV) are synthesized via selective lithiation/bromination and subsequent Suzuki—Miyaura coupling of key intermediate (II) with arylboronic acids (III).
ChemInform Abstract: Enantio‐ and Diastereoselective Michael Additions of C‐Succinimidyl Esters to Nitro Olefins Using Cinchonine‐Derived Bifunctional Organocatalysts.
Authors: Jakubec Pavol , Cockfield Dane M. , Hynes Peter S. , Cleator Ed , Dixon Darren J. 
Published: January 2012

AbstractThe screening of a library of 9‐amino(9‐deoxy)epicinchonine derivatives (11 examples) presents thiourea CIN as the most reactive and enantioselective catalyst, although a number of the other catalysts are nearly suitable.
ChemInform Abstract: Lewis Acid Catalyzed Direct Cyanation of Indoles and Pyrroles with N‐Cyano‐N‐phenyl‐p‐toluenesulfonamide(NCTS).
Authors: Yang Yang , Zhang Yan , Wang Jianbo 
Published: January 2012

AbstractThe process is successful for various indole and pyrrole substrates in the presence of catalytic or stoichiometric amounts of BF3·OEt2.
ChemInform Abstract: Tandem Visible Light‐Mediated Radical Cyclization—Divinylcyclopropane Rearrangement to Tricyclic Pyrrolidinones.
Authors: Tucker Joseph W. , Stephenson Corey R. J. 
Published: January 2012

AbstractPartial reduction of product (IIa) provides the pyrrole (III); unprotected lactams like (IV) are generated by removal of the propargyl group.
ChemInform Abstract: Copper‐Mediated Aerobic Synthesis of 3‐Azabicyclo[3.1.0]hex‐2‐enes and 4‐Carbonylpyrroles from N‐Allyl/Propargyl Enamine Carboxylates.
Authors: Toh Kah Kah , Wang Yi‐Feng , Ng Eileen Pei Jian , Chiba Shunsuke 
Published: January 2012

AbstractN‐Allyl enamine carboxylates are applied to the copper‐promoted reaction to give 3‐azabicyclo[3.1.0]hex‐2‐enes with complete diastereoselectivity.
ChemInform Abstract: One‐Pot Synthesis of Trisubstituted Pyrazoles via Multicomponent Approach.
Authors: Santhosh P. , Chunduru V. S. R. , Rao V. Rajeswar 
Published: January 2012

AbstractA novel one‐pot multicomponent reaction for the synthesis of 1‐aryloxymethyl substituted pyrazoles (III) (12 examples) is presented.
ChemInform Abstract: Synthesis of Some 3‐(5‐Chloro‐1,3‐diaryl‐1H‐pyrazol‐4‐yl)‐1‐arylprop‐2‐en‐1‐ones and 1,5‐Bis(5‐chloro‐1,3‐diaryl‐1H pyrazol‐4‐yl)pent‐1,4‐diene‐3‐ones and Their Antimicrobial Activity.
Authors: Rani Archna , Jain Sapna , Dureja Prem , Kumar Rita , Kumar Anil 
Published: January 2012

AbstractSome of the synthesized compounds show promising antimicrobial activities.
ChemInform Abstract: Synthesis of N‐Unsubstituted 2‐Arylpyrazolo[1,5‐a]benzimidazoles from 1‐Benzylideneamino‐2‐methylbenzimidazole and the Role of Acylotropic and Acylotropic‐Prototropic Isomerization.
Authors: Kuz'menko T. A. , Divaeva L. N. , Morkovnik A. S. 
Published: January 2012

AbstractThe title compounds (IV) are obtained for the first time starting from 2‐methylbenzimidazole (I) by benzoylation of the methyl group followed by cyclization of the resulting vinyl acylates (III).
ChemInform Abstract: Unexpected Rearrangement: A Novel Route to 3‐Thiazoline.
Authors: Liu Yingrui , Zhao Baoxiang , Li Yonghai , Zheng Liangwen , Liu Jinting 
Published: January 2012

AbstractThe attempt to prepare 1,4‐thiazine products is unsuccessful and the title compounds are formed instead via a rearrangement process.
ChemInform Abstract: Synthesis and Antimicrobial Activity of a New Class of Methyleneamine‐Linked Bis‐Heterocycles.
Authors: Reddy A. Babul , Hymavathi R. V. , Chandrasekhar T. , Naveen M. , Swamy G. Narayana 
Published: January 2012

AbstractCompound (IIIc) shows activity against P.
ChemInform Abstract: Heterogeneous Catalyst: Silica Sulfuric Acid Catalyzed Synthesis of 9,10‐Dihydro‐12‐aryl‐8H‐benzo[α]xanthen‐11(12H)‐one Derivatives under Solvent‐Free Conditions.
Authors: Nazeruddin G. M. , Pandharpatte Mahesh S. , Mulani Khudbudin B. 
Published: January 2012

AbstractThe title compounds (IV) are obtained by three‐component condensation reaction of β‐naphthol, cyclic 1,3‐dicarbonyl compounds, and aromatic aldehydes using silica sulfuric acid as an efficient and reusable heterogeneous catalyst.
ChemInform Abstract: Convenient Synthesis of Aminopyridinecarboxylic Acids.
Authors: Okamoto Iwao , Terashima Masayuki , Yoshioka Rempei , Muramatsu Tomonori , Kojima Satomi , Inoue Haruka , Takahashi Mio , Morita Nobuyoshi , Tamura Osamu 
Published: January 2012

AbstractMonoamination of dibromopyridines (I) and (VIII) followed by carbonylation and subsequent hydrolysis of methyl esters (VI) and (X) furnish (alkylamino)pyridinecarboxylic acids (VII) and (XI) in satisfactory to good yields, though the 3,5‐dibromopyridine (VIII) reacts more slowly.
ChemInform Abstract: 4‐(Azulen‐1‐yl) Six‐Membered Heteroaromatics Substituted with Thiophen‐2‐yl or Furan‐2‐yl Moieties in 2 and 6 Positions.
Authors: Razus Alexandru C. , Birzan Liviu , Cristea Mihaela , Tecuceanu Victorita , Hanganu Anamaria , Enache Cristian 
Published: January 2012

AbstractThe compounds (IV) and (V) are intensely colored.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Some Heterocyclic 2,6‐Bis(substituted)‐1,3,4‐thiadiazolo‐, Oxadiazolo‐, and Oxathiazolidino‐Pyridine Derivatives from 2,6‐Pyridine Dicarboxylic Acid Dihydrazide.
Authors: Ghozlan Said A. S. , Al‐Omar Mohammed A. , Amr Abd El‐Galil E. , Ali Korany A. , El‐Wahab Ahmed A. Abd 
Published: January 2012

AbstractThe new compounds are screened for their antimicrobial activity against the Gram‐positive bacteria B.
ChemInform Abstract: Synthesis of 3,5‐Diaroylpyridines.
Authors: Garkushenko K. , Makarova M. A. , Sorokina O. P. , Poendaev N. V. , Vorontsova M. A. , Sagitullina G. P. 
Published: January 2012

AbstractPreviously unknown symmetrical 3,5‐diaroylpyridines (IV) are synthesized according to a modified Hantzsch reaction followed by an oxidation step.
ChemInform Abstract: 3‐(2‐Methylthiopyridin‐3‐yl)‐3‐oxopropionic Esters.
Authors: Zubarev A. A. , Zav'yalova V. K. , Shestopalov A. M. 
Published: January 2012

AbstractHydrolysis of 3‐amino‐3‐(2‐methylthiopyridinyl)propenoic esters (III), obtained by the Blaise reaction, provides access to the corresponding β‐keto carboxylic esters (IV).
ChemInform Abstract: Green Synthesis and Characterization of Novel α‐Acyloxycarboxamides Through Three‐Component Reaction Between Pyridine Carbaldehydes, Cyclohexyl Isocyanide, and Benzoic Acid Derivatives.
Authors: Vessally Esmail , Ramazani Ali , Yaaghubi Elham 
Published: January 2012

AbstractNovel α‐acyloxycarboxamides (IV) (15 examples) are synthesized via Passerini reaction in water.