bluuebunny/crossref_metadata_2025_split huggingface dataset:
How to repair medial meniscal ramp lesions: A systematic review of surgical techniques
Authors: Pizza Nicola , Urda Luis L. , Sanchez Francisco S. , Ibañez Maximiliano , Zaffagnini Stefano , Perelli Simone , Monllau Juan C. 
Published: June 2024

AbstractPurposeto provide a comprehensive overview of all the surgical techniques published in the literature for repairing meniscal ramp lesions focusing on the technical aspects and the pros and cons of every procedure. Such lesions can be managed using various approaches, each of this with its specific advantages and disadvantages.MethodsPubmed Central, Scopus, and EMBASE databases were systematically reviewed according to the preferred reporting items for systematic reviews and meta‐analysis (PRISMA) guidelines for studies on surgical techniques for repairing meniscal ramp lesions through May 2023. Overall, 32 articles matched the selection criteria and were included in the study.ResultsDebridement alone may be sufficient for small stable meniscal ramp lesions but, for tears in the menisco‐capsular junction that affect the stability of the medial meniscus, it seems reasonable to repair it, even though the clinical results available in literature are contrasting. All‐inside sutures through anterior portals seems to be an effective solution for meniscal ramp lesions with MTL tears. All‐inside sutures through posteromedial portals are particularly useful for large meniscal ramp lesions, in which an inside‐out suture can also be performed.ConclusionMeniscal ramp lesions can be managed using various approaches, each of this with its specific advantages and disadvantages. Further research is required to determine the optimal technique that can be considered as the gold standard and can provide the better results.Level of EvidenceLevel III, systematic review.
Influence of variable hinge positioning on coronal and sagittal alignment in uniplanar medial open‐wedge high tibial osteotomy
Authors: Frings Jannik , Korthaus Alexander , Linke Philip , Rolvien Tim , Stürznickel Julian , Strahl André , Krause Matthias , Frosch Karl‐Heinz 
Published: June 2024

AbstractPurposeThere is a high risk of increasing the posterior tibial slope (PTS) during medially opening‐wedge high tibial osteotomy (mowHTO). Most recently, the idea of intentional simultaneous coronal and sagittal correction, using uniplanar cutting techniques has emerged. This study aims to examine the influences of variable hinge positioning and osteotomy gap height on the sagittal and coronal plane.MethodsTwenty uniplanar mowHTOs were performed in standardised (left) solid‐foam proximal tibia models. In the different models, hinge position was rotated stepwise by 10°, between 90° (cutting straight medial to lateral) and 0° (cutting straight anterior to posterior) (n = 10). Additionally, gap heights of 5 and 10 mm were produced and analysed. Logistic regression analysis was performed to calculate a predictive regression formula for the relation between gap height, hinge rotation and the changes of medial proximal tibia angle (MPTA), medial and lateral PTS.ResultsBetween cutting angles of 90 and 20°, the MPTA was mainly influenced by the gap height (0.95° MPTA per 1 mm gap height), but not by the cutting angle. Between 20 and 0°, the MPTA was decreased by 3.6° per 10° of rotation, but not by the gap height. Between cutting angles of 90 and 10°, the PTS was increased linearly by 0.97° per 10° of rotation and by 0.61° per 1 mm gap height.ConclusionIn mowHTO with lateral hinge positions, the MPTA is mainly influenced by gap height. Changes of PTS can be avoided by a straight lateral hinge position. In posterior hinge locations (0‐20°), changes of MPTA are mainly caused by hinge rotation, but not by gap height.Level of EvidenceLevel III, Case–control study.
The LTAR Grazing Land Common Experiment at Archbold Biological Station‐University of Florida
Authors: Boughton Elizabeth H. , Silveira Maria L. , Swain Hilary , DeLong Alia , Sclater Vivienne , Azad Shefali , Bracho Rosvel , Saha Amartya , Sonnier Grégory 
Published: June 2024

AbstractThe Archbold Biological Station‐University of Florida (ABS‐UF) Long‐term Agroecosystem Research (LTAR) site lies in the heart of south‐central Florida, representing subtropical humid grazing lands in North America and globally. Beef producers in this region face challenges due to climate variability, limited nutritive value of forages, poor soils, public concerns about water quality and greenhouse gas emissions, management trade‐offs, economic uncertainty, and increasing urban encroachment. The ABS‐UF Common Experiment, co‐designed with stakeholders, will assess innovative management systems in comparison to prevailing management systems on key indicators of sustainability. Innovative management systems being tested are alternative fire (frequency and spatial extent) and grazing practices (stocking rate and system). The common experiment framework was implemented across a management intensity gradient spanning from native rangeland to cultivated pastures, including embedded wetlands. Issues that have arisen to date include difficulties in implementing prescribed fire and reduced productivity in cultivated pastures associated with innovative management, which led to an adjustment of the experimental treatment. A stakeholder advisory council will codesign future alternative treatments and guide experimental changes in this long‐term experiment. Stakeholder engagement efforts revealed research priorities centered on financial strength, carbon (C) and greenhouse gas emissions, and water quality. Stakeholders are also interested in testing emerging technology such as the utility of virtual fencing. Results from ABS‐UF provide a unique perspective from subtropical humid grazing lands for continental‐scale cross‐site synthesis on sustainable agroecosystems across LTAR.
Do acting interns need residents? A comparison of acting intern experience on hospital medicine resident versus nonresident teams
Authors: Gray Adam , Hall Alan M. , Chadha Jagriti , Leung Stephanie , Karnik Kelsey , Mangino Anthony A. , Ragsdale John W. 
Published: June 2024

AbstractBackgroundThe clinical demands for hospitalist groups have grown at academic medical centers, without similar growth of teaching opportunities for faculty. Traditional resident teaching teams are often crowded with learners which can limit acting intern (or subintern) patient encounters. Medical students are often placed on nonresident teaching teams, although there are few studies on learner experience on a nonresident teaching team model.MethodsTo address these concerns, we created two nonresident teaching teams composed of one attending and two acting interns. We compared acting intern experience on the nonresident teaching teams to the traditional resident teams to determine if there were significant differences in student experience by reviewing course evaluation data on the two team models.ResultsOf the 276 students who completed the Internal Medicine Acting Internship from 2019 to 2023, 224 students (81%) completed the course evaluation. The course was highly rated, and the ratings were similar in both models demonstrating that the nonresident teaching team model is an effective option for acting interns.ConclusionThe nonresident teaching team model can offload crowded teaching teams, add additional acting intern experiences, and add teaching opportunities for hospital medicine attendings.
The prevalence of HIV resistance mutations and their influence on the shedding of HIV‐1 into peritoneal dialysis effluent
Authors: Mooko Teboho , Bisiwe Feziwe Busiswa , Chikobvu Perpertual , Morobadi Molefi Daniel , Mofokeng Thabiso Rafaki Petrus , Nyaga Martin Munene , Kemp Gabre , Goedhals Dominique , Ndlovu Kwazi Celani Zwakele 
Published: June 2024

AbstractHIV drug resistance mutations (HIVDRMs) are important determinants of therapeutic effects and outcomes even in end‐stage kidney failure (ESKF) people living with HIV (PLWHIV). This study evaluated the prevalence of HIVDRMs and their effect on the shedding of HIV‐1 into peritoneal dialysis (PD) effluents. This cross‐sectional study of PLWHIV and having ESKF and managed with antiretroviral therapy (ART) and PD, collected enrolled patients’ demographic information, clinical and laboratory data, and sequenced HIV‐1 RNA in unsuppressed plasma and PD effluent samples. HIV viral load and HIVDRMs were determined using qualitative polymerase chain reaction (qPCR) and Stanford University HIVDRM Database, respectively. There were 60 participants recruited with a median age of 43.0 (interquartile range [IQR], 38.0–47) years and were predominantly on abacavir (88.3%), lamivudine (98.3%), and efavirenz (70%) for a median duration of 8 (IQR, 5–11) years. Among participants with detectable HIV‐1 in PD effluents, the prevalence of HIVDRMs was 62.5% (5/8) compared to 7.7% (4/52) among those with undetectable HIV‐1 (p = 0.001) with non‐nucleoside reverse transcriptase inhibitor (NNRTI) resistance mutations predominating. On Spearman's correlation analysis, high plasma HIV levels (ρ = 0.649, p < 0.001), T‐cell CD4 count (ρ = −0370, p < 0.004), serum creatinine (ρ = −0.396, p < 0.002), and white blood cell count (ρ = −0.294, p < 0.023) levels were significant factors correlated with the detection of HIV‐1 in PD effluents. Moreover, HIVDRMs presence (ρ = 0.504, p < 0.001) particularly NNRTI resistance (ρ = 0.504, p < 0.001) were also significantly correlated with detection of HIV‐1 in PD effluents. The presence of HIVDRMs, high plasma HIV viral load, and T‐cell CD4 count were correlated with HIV‐1 shedding into PD effluents.
Existential themes of the 2020s syndemic polycrisis
Authors: Field Thomas A. , Ghoston Michelle R. 
Published: June 2024

AbstractThe coronavirus and anti‐Black racial violence dual pandemics of the early 2020s brought multiple existential concerns that aligned with the four existential givens of human experience, namely, life and death anxiety, community and isolation, meaning‐making and absurdity, freedom of choice and responsibility compared to determinism, and existential guilt and shattering. These themes are examined through an analysis and summary of the seven articles included in this special issue. These seven articles substantiate a need for further research and widely implemented interventions that emphasize culturally affirming and sustaining humanistic and existential counseling practices paired with advocacy for systemic change that enhances community solidarity alongside meaning‐making and identity preservation. This approach aims to support people from marginalized communities in navigating compounded challenges during dual crises such as the early 2020s syndemic polycrisis.
A simple step to improve fat and energy delivery of human milk delivered via bottle‐feeding pump: An experimental study
Authors: Irwin Caitlin , Beard Kate , Martin Louis , Kua Kok Lim , Huff Katie 
Published: June 2024

AbstractBackgroundEnteral feeding pump systems deliver decreased amounts of macronutrients in human milk to neonates. This study determined the macronutrient loss associated with a bottle‐feeding pump system and the effect of manually mixing the human milk during extended feeds.MethodsMacronutrient content from samples of donor human milk was analyzed after simulated extended feeds with a bottle‐feeding pump system, using a human milk analyzer. Simulations were repeated using manual mixing of the bottle every 30 min during feeding. The percentage of the baseline was calculated, and one‐sample t tests and analysis of variance compared the effect of manual mixing and the duration of feeding on macronutrient delivery.ResultsThe delivery of fat and energy was lower over time, but manual mixing considerably improved retention. The length of feeding impacted fat delivery, with less fat delivered over time (P < 0.001). Manually mixing significantly increased fat delivery (P < 0.001). Similar results were found for energy, with a significant reduction in energy delivery over time (P < 0.001) and significantly more energy delivered with mixing (P < 0.001). Mixing and the duration of feeding had minimal effect on protein or carbohydrate delivery.ConclusionsBottle‐feeding pump systems are associated with a significant reduction in the delivery of fat and energy of donor human milk. The manual mixing of donor human milk during prolonged feeds is a simple way to improve fat and energy delivery to the neonate.
Automation tools to support undertaking scoping reviews
Authors: Khalil Hanan , Pollock Danielle , McInerney Patricia , Evans Catrin , Moraes Erica B. , Godfrey Christina M. , Alexander Lyndsay , Tricco Andrea , Peters Micah D. J. , Pieper Dawid , Saran Ashrita , Ameen Daniel , Taneri Petek Eylul , Munn Zachary 
Published: June 2024

AbstractObjectiveThis paper describes several automation tools and software that can be considered during evidence synthesis projects and provides guidance for their integration in the conduct of scoping reviews.Study Design and SettingThe guidance presented in this work is adapted from the results of a scoping review and consultations with the JBI Scoping Review Methodology group.ResultsThis paper describes several reliable, validated automation tools and software that can be used to enhance the conduct of scoping reviews. Developments in the automation of systematic reviews, and more recently scoping reviews, are continuously evolving. We detail several helpful tools in order of the key steps recommended by the JBI's methodological guidance for undertaking scoping reviews including team establishment, protocol development, searching, de‐duplication, screening titles and abstracts, data extraction, data charting, and report writing. While we include several reliable tools and software that can be used for the automation of scoping reviews, there are some limitations to the tools mentioned. For example, some are available in English only and their lack of integration with other tools results in limited interoperability.ConclusionThis paper highlighted several useful automation tools and software programs to use in undertaking each step of a scoping review. This guidance has the potential to inform collaborative efforts aiming at the development of evidence informed, integrated automation tools and software packages for enhancing the conduct of high‐quality scoping reviews.
Light‐Triggered Reversible Swelling of Azobenzene‐Containing Block Copolymer Worms via Confined Deformation Prepared by Polymerization‐Induced Self‐Assembly
Authors: Deng Zichao , Sun Yalan , Chen Aihua 
Published: June 2024

AbstractStimuli‐responsive block copolymer nanoparticles (NPs) have received close attention in recent years owing to their tremendous application potential in smart materials. Azobenzene‐containing NPs are widely studied due to the advantages of light as a stimulus and fast reversible trans–cis isomerization of azobenzene chromophores. However, the inefficient preparation process and difficult reversible transformation of morphologies limit their development. Herein it is demonstrated that the light‐triggered reversible swelling behavior of wormlike NPs with high azobenzene content could be realized via confined deformation. These worms are prepared in large quantities via polymerization‐induced self‐assembly based on the copolymerization of 11‐(4‐(4‐butylphenylazo)phenoxy)undecyl methacrylate (MAAz) and N‐(methacryloxy)succinimide (NMAS) monomers. Upon UV/visible light irradiation, the reversible deformation of worms is achieved when the feed molar ratio of NMAS/MAAz is relatively high or via crosslinking using diamines, which leads to the reduction of the photoisomerization efficiency. The diameter variation of the worms is influenced by the amount and types of crosslinkers. Moreover, the scalability of this strategy is further proved by the fabrication of photo‐ and reductant‐responsive crosslinked worms. It is expected that this study not only provides a new route to affording reversible photoresponsive NPs but also offers a unique insight into the reversible photodeformation mechanism of azobenzene‐containing NPs.
Bond sensitive graph neural networks for predicting high temperature superconductors
Authors: Gu Liang , Liu Yang , Chen Pin , Huang Haiyou , Chen Ning , Li Yang , Lookman Turab , Lu Yutong , Su Yanjing 
Published: June 2024

AbstractFinding high temperature superconductors (HTS) has been a continuing challenge due to the difficulty in predicting the transition temperature (Tc) of superconductors. Recently, the efficiency of predicting Tc has been greatly improved via machine learning (ML). Unfortunately, prevailing ML models have not shown adequate generalization ability to find new HTS, yet. In this work, a graph neural network model is trained to predict the maximal Tc (Tcmax) of various materials. Our model reveals a close connection between Tcmax and chemical bonds. It suggests that shorter bond lengths are favored by high Tc, which is in coherence with previous domain knowledge. More importantly, it also indicates that chemical bonds consisting of some specific chemical elements are responsible for high Tc, which is new even to the human experts. It can provide a convenient guidance to the materials scientists in search of HTS.
Significance of overvaluation of weight and shape in childhood binge‐eating disorder: Results from a population‐based study
Authors: Baron Alejandra , Smith Kathryn E. , Mason Tyler B. 
Published: June 2024

AbstractBinge‐eating disorder (BED) involves recurrent binge‐eating episodes with significant distress and is associated with adverse psychological and social problems. Previous studies in adults have suggested that presence of overvaluation of shape and weight may be a clinically relevant subtype of BED. The purpose of this study was to examine if overvaluation represents an important subtype of BED in children. It was hypothesized that children with both BED and overvaluation will have a higher body mass index z‐scores (BMI‐z) and internalizing psychopathology and lower cognitive functioning scores. Participants included a diverse sample of children between the ages of 9 and 10 years old from the baseline wave of the Adolescent Brain Cognitive Development study. Caregivers completed the Kiddie Schedule for Affective Disorders and Schizophrenia, the Child Behavior Checklist, and measures of demographics, and children completed neurocognitive tests and had their height and weight measured. The analytic sample included 7200 children. There were no interactions between BED status and overvaluation in relation to outcome variables. Yet, BED and overvaluation were independently associated with higher internalizing symptoms, higher BMI‐z, and poorer cognitive functioning. Contrary to the expectations, results did not support significant interactions between BED status and overvaluation in children. However, the study highlights the independent clinical significance of BED and overvaluation with higher BMI‐z, higher internalizing symptoms, and poorer cognitive functioning. Future studies are necessary to determine the developmental trajectories of BED and overvaluation into adolescence and adulthood.
Non‐iterative stress‐displacement solution for surrounding rock mass with multiple non‐circular deep tunnels
Authors: Ye Zi Kun , Ai Zhi Yong 
Published: June 2024

AbstractA non‐iterative stress‐displacement solution is proposed in this paper to investigate surrounding rock mass with multiple non‐circular deep tunnels. Compared with the Schwarz alternating method, the proposed method only spends one‐time matrix operation, showing considerable efficiency and accuracy of the matrix solution. First, a matrix solution is formulated to obtain the conformal mapping function for the non‐circular tunnel. Then, in consideration of multiple boundary conditions, the generalized complex variable theory and fast Fourier transform (FFT) algorithm are used to formulate a matrix solution of potential functions. The stress and displacement fields around multiple non‐circular tunnels can be further determined from the matrix solution. A series of numerical examples are conducted to verify the proposed method, perform the convergency study, and discuss the effects of tunnel geometries, distances, and arrangements. The convergency study shows that the more accurate conformal mapping function requires more sampling points in the FFT. In addition, the high stress zone would be amplified if the arrangement of multiple tunnels makes the high stress zone adjacent or overlapped.
On monitoring high‐dimensional processes with individual observations
Authors: Ebadi Mohsen , Chenouri Shoja'eddin , Steiner Stefan H. 
Published: June 2024

AbstractModern data collecting methods and computation tools have made it possible to monitor high‐dimensional processes. In this article, we investigate phase II monitoring of high‐dimensional processes when the available number of samples collected in phase I is limited in comparison to the number of variables. A new charting statistic for high‐dimensional multivariate processes based on the diagonal elements of the underlying covariance matrix is introduced and we propose a unified procedure for phases I and II by employing a self‐starting control chart. To remedy the effect of outliers, we adopt a robust procedure for parameter estimation in phase I and introduce the appropriate consistent estimators. The statistical performance of the proposed method is evaluated in phase II using the average run length (ARL) criterion in the absence and presence of outliers. Results show that the proposed control chart scheme effectively detects various kinds of shifts in the process mean vector. Finally, we illustrate the applicability of our proposed method via a manufacturing application.
Real‐time quantification of in vivo cerebrospinal fluid velocity using the functional magnetic resonance imaging inflow effect
Authors: Diorio Tyler C. , Nair Vidhya Vijayakrishnan , Patel Neal M. , Hedges Lauren E. , Rayz Vitaliy L. , Tong Yunjie 
Published: June 2024

AbstractIn vivo estimation of cerebrospinal fluid (CSF) velocity is crucial for understanding the glymphatic system and its potential role in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. Current cardiac or respiratory‐gated approaches, such as 4D flow magnetic resonance imaging (MRI), cannot capture CSF movement in real time because of limited temporal resolution and, in addition, deteriorate in accuracy at low fluid velocities. Other techniques like real‐time phase‐contrast‐MRI or time‐spatial labeling inversion pulse are not limited by temporal averaging but have limited availability, even in research settings. This study aims to quantify the inflow effect of dynamic CSF motion on functional MRI (fMRI) for in vivo, real‐time measurement of CSF flow velocity. We considered linear and nonlinear models of velocity waveforms and empirically fit them to fMRI data from a controlled flow experiment. To assess the utility of this methodology in human data, CSF flow velocities were computed from fMRI data acquired in eight healthy volunteers. Breath‐holding regimens were used to amplify CSF flow oscillations. Our experimental flow study revealed that CSF velocity is nonlinearly related to inflow effect‐mediated signal increase and well estimated using an extension of a previous nonlinear framework. Using this relationship, we recovered velocity from in vivo fMRI signal, demonstrating the potential of our approach for estimating CSF flow velocity in the human brain. This novel method could serve as an alternative approach to quantifying slow flow velocities in real time, such as CSF flow in the ventricular system, thereby providing valuable insights into the glymphatic system's function and its implications for neurological disorders.