bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prognostic significance of additional localized treatment to primary lesion in patients undergoing hormone therapy for metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis
Authors: Yamada Yuta , Urabe Fumihiko , Kimura Shoji , Iwatani Kosuke , Kimura Naoki , Miki Jun , Kimura Takahiro , Kume Haruki 
Published: June 2024

Background
We aimed to compare the prognostic values of ‘localized treatment to the primary lesion (LT) plus hormone therapy (HT)’ versus ‘HT alone’ in metastatic hormone-sensitive prostate cancer (mHSPC).

Methods
We conducted a systematic search through the databases of PubMed®, Web of Science®, and Cochrane library® in April 2023 based on the PRISMA (Preferred Reporting Items for Systemic Reviews and Meta-Analyses) statement. A pooled meta-analysis was performed to assess the prognostic differences between LT + HT and HT alone according to randomized and non-randomized controlled studies (RCTs and NRCTs, respectively).

Results
The search identified three RCTs and eight NRCTs. In RCTs, LT did not show prognostic benefits regarding biochemical-failure free rate nor overall survival (OS), although in patients with low tumor burdens, the LT + HT group showed better OS (HR: 0.68, 95% CI: 0.54–0.86). In the NRCTs, the LT+HT group showed superior progression-free survival (hazard ratio (HR): 0.42, 95% confidence interval (CI): 0.21–0.87), cancer-specific survival (HR: 0.39, 95% CI: 0.20–0.76), and OS (HR: 0.63, 95% CI: 0.57–0.69) to the HT alone group. In addition, better OS was observed in the LT +HT group regardless of the type of treatment modality for LT; radical prostatectomy (HR: 0.52, 95% CI: 0.39–0.69), radiotherapy (HR: 0.63, 95% CI: 0.56–0.71) in NRCTs.

Conclusions
LT to the primary lesion in metastatic hormone-sensitive prostate cancer may provide prognostic benefits and especially in patients with low tumor burden.
An investigation into waste handler’s knowledge of management of isolation waste: A case study of Dr George Mukhari Academic Hospital, Gauteng, South Africa
Authors: Moloisi Mmatlou Ouma , Onwubu Stanley Chibuzor 
Published: June 2024

Background
The proper management of isolation waste is of utmost importance in healthcare facilities to prevent the spread of infections and protect both healthcare workers and the general public. This study investigated waste handlers’ knowledge of the management of isolation waste at Dr. George Mukhari Academic Hospital in Gauteng, South Africa.

Methods
A survey was conducted to assess waste handlers’ understanding of waste types, colour codes, safety precautions, and awareness of internal policies related to isolation waste management.

Results
The study found that the majority of waste handlers demonstrated a good understanding of waste types generated in the isolation unit, including sharps waste, human tissue waste, infectious waste, and general waste. They also correctly identified examples of sharp waste, such as injections, blades, glass slides, and needles. Additionally, most respondents were aware of the colour code used for representing infectious waste as "yellow" and "red." The study revealed a statistically significant association between waste handlers’ age and their knowledge of isolation waste, suggesting that age may influence their understanding of waste management practices. Furthermore, experience was found to be significantly associated with waste handlers’ knowledge of the health-hazardous nature of isolation waste. While the majority of waste handlers recognized the importance of wearing protective clothing and correctly marking isolation waste, some respondents were not aware of the internal policy for waste handling such as guidelines and protocols specific to the segregation, packaging, labeling, and disposal of waste generated within the isolation units.

Conclusion and contribution
These findings highlight the importance of continuous training, targeted education, and policy dissemination to ensure effective waste management and adherence to safety protocols among waste handlers.
Characterization of thymic architecture and lymphocyte populations in X-MAID due to an underlying pathogenic moesin mutation
Authors: Al Ghamdi Abdulrahman , Vong Linda , M. Roifman Chaim , Ngan Bo 
Published: June 2024

Background: X-linked Moesin Associated Immunodeficiency (X-MAID) is a combined immunodeficiency caused by deficiency in the moesin protein. Moesin, which is encoded by the MSN gene, is part of the ezrin-radixin-moesin (ERM) family of transmembrane proteins that interact with the actin cytoskeleton and regulate the shape and migration of cells. Deficiency of moesin is associated with aberrant T cell migration and inadequate immune synapse formation, leading to significant immunodeficiency and recurrent infections. While the clinical presentation of X-MAID is diverse, to date, no thymus histopathology findings have been reported. Aim: Describe the thymus histopathology of a patient with X-MAID. Results: Our patient is a 10-year-old male who presented early in life with recurrent infections, dysmorphic features, and severe pulmonary venous stenosis which required a double lung transplant at the age of 4 years. Prior to transplant, he was referred to Immunology for assessment and was subsequently found to harbour a hemizygous variant in the MSN gene (c.278dupT; p.L93FfsX21). Thymus histopathology findings showed significant cortical atrophy and dysplasia and was accompanied by reduction in CD3+ cells in the cortex. Abnormally low numbers of suppressor T cells and T helper cells in the thymic cortex and medulla were noted. Conclusion: Thymic findings in X-MAID can include cortical atrophy, dysplasia, and decreased cellularity. This provides further evidence for the importance of moesin on T cell development and migration in the thymus. Statement of novelty: Description of thymus histopathology in a patient with X-MAID.
Generalized derivation on semiprime and prime Banach algebras
Authors: Koç Sögütcü Emine 
Published: June 2024

Abstract
In this study, the commutativity conditions with generalized derivations, which have not been examined before, are discussed.
Under these conditions, the subject of generalized derivations in (semi)prime Banach algebras is studied.
New fundamental results will be provided for researchers in this field and generalize some of the results found in the literature.
The apple doesn’t fall far from the tree: is there a connection between the body mass indexes of adolescents and their parents?
Authors: Tazeoglu Aybala , Ergul Yasemin 
Published: June 2024

Abstract

Objectives
Adolescent cases suffering from obesity tend to increase in middle-income countries. This study focused on the relationship between adolescent obesity and parents body mass index (BMI) and the variables of satisfaction, diet implementation and sports promotion.

Methods
This cross-sectional study was conducted among adolescents living in the Mediterranean region (n=522, evaluated n=488). Anthropometric measurements were taken by expert researchers and data were collected using face-to-face survey technique.

Results
The average BMI of the adolescents and parents’ was found to be above normal values. In adolescents, there was a positive and very good correlation with maternal BMI (r=0.711, p<0.01), a positive and moderate correlation with paternal BMI (r=0.512, p<0.01); In girl adolescents, it was positively and very well with maternal BMI (r=0.731, p<0.01), positively and moderately with father BMI (r=0.549, p<0.01); In boy adolescents, a positive and good correlation was found with maternal BMI (r=0.698, p<0.01), and a positive and moderate correlation with paternal BMI (r=0.459, p<0.01). In the analyzes comparing those who thought obesity threatened them (group 1) and those who did not think it threatened them (group 2), there was a statistically significant difference between the groups in terms of BMI distribution, satisfaction with body weight, diet program implementation, diet recommendation by the family and sports encouragement (p<0, 05).

Conclusions
In a cross-sectional perspective paternal obesity is also significant in adolescents and the correlation with maternal obesity is relatively more effective. Also includes evidence of individual efforts and parental contribution in adolescents who see obesity as a threat.
The false tiger of almond, Monosteira unicostata (Hemiptera: Tingidae): Biology, ecology, and control methods
Authors: Bouali Zakaria , Assouguem Amine , Joutei Abdelmalek Boutaleb , Ullah Riaz , Alqahtani Ali S. , Lahlali Rachid 
Published: June 2024

Abstract
The almond tree, following the olive tree, holds the distinction of being the fruit species occupying the largest area in Morocco, spanning 128,000 ha and hosting 16 million trees. This sector holds immense socio-economic significance both nationally and globally. Despite its prominence, the almond tree faces severe phytosanitary challenges, prominently among them, the False tiger bug of the almond tree, Monosteira unicostata (Mulsant & Rey [Hemiptera: Tingidae]). This polyphagous, sedentary, and gregarious hemipteran, boasting five larval instars and typically generating four generations annually, exhibits a life cycle duration ranging from 2 to 3 months contingent on the season. This pest inflicts notable harm on almond tree leaves by extracting their chlorophyll content through its piercing mouthparts and depositing excrement, impeding respiratory function and adversely impacting fruit development, maturation, and overall production. Diverse control strategies have been implemented to tackle this issue, commencing with prophylaxis involving resistant varieties and sound agricultural practices. Subsequently, biological control methods leveraging natural enemies such as Piocoris luridus and species from families including Coccinellidae, Anthocoridae, Lygaeidae, Miridae, and Nabidae have been employed. Plant-based biopesticides such as azadirachtin (Azadirachta indica), thyme oil (Thymus zygis), Jatropha oil (Jatropha curcas), and concentrated extracts of Artemisia absinthium, as well as mineral-based approaches involving treated kaolin sprays through particle film technology, contribute to the arsenal of control measures. In cases of severe infestations, synthetic active ingredients such as organophosphates, pyrethroids, carbamates, abamectin, and deltamethrin, among others, have proven efficacy in managing this pest.
Against the Nudity in Art: Eliasian Reading of National Conservative Catholic Habitus
Authors: Laddach Agnieszka 
Published: June 2024

Abstract

The Cleaner Marina Abramović Retrospective Exhibition in the Centre of Contemporary Art in Toruń, Poland, sparked much protest. This article analyses the protesters’ attitudes to capture their habitus. The analysis employs Norbert Elias’ sociological theory on national habitus. Demonstrations of protest invite interpretations of the peculiar national conservative Catholic habitus that – in the light of my study – stems in Poland from selective post-Tridentine pre-Vatican II Catholic magisterial thought and a sociopolitical historiography of traditional Polish culture. I recognise that the aim of the national conservative Catholics is to preserve a specific kind of Polish culture based on its early-modern image: strong state influenced by the Catholic Church in both policy and culture, with the accompanying theology of art taken from the Tridentine Council and the post-Tridentine debate. As a result, the national conservative Catholics invest much energy in remembrance politics and historical politics. I conclude that this habitus requires theological and religious reworking of national conservative Catholics’ understanding of the term “catholic.”
Handlungsspielräume deutscher Sicherheitspolitik nach Russlands Angriff auf die Ukraine 2022
Authors: Jäger Thomas 
Published: June 2024

Zusammenfassung
Deutschland muss seinen außen- und sicherheitspolitischen Handlungsspielraum in einer gebrochen bipolaren internationalen Ordnung ausgestalten. Dabei gibt die EU den Rahmen ab, weil sie die europäische Staatenordnung prägt. Sie hebt das Bemühen der einzelnen Staaten aber nicht auf, denn sie garantiert keine Sicherheit. Russland entwickelt sich zur langfristigen Bedrohung, weil innere und äußere Entwicklungen gleichermaßen auf Gewalt gerichtet sind. Die USA kämpfen gleichzeitig in drei Regionen um die Stabilisierung der Ordnung: in Europa, im Pazifik und im Mittleren Osten. Europa hat dabei nicht viel zu bieten. Das amerikanische Interesse zu verhindern, dass China Eurasien beherrscht, ist die Chance von Deutschland und der EU, Demokratie, Sicherheit und Wohlstand zu bewahren.
Die „Zeitenwende“ und die Suche nach einem Paradigma für die postliberale internationale Ordnung
Authors: Horlohe Thomas 
Published: June 2024

Zusammenfassung
Als Staats- und Regierungsform ist die liberale Demokratie bereits seit einiger Zeit herausgefordert, von innen und von außen. Russlands Überfall auf die Ukraine wurde vom Niedergang der liberalen internationalen Ordnung und von der Schwäche ihrer Führungsmacht USA ermuntert. Vor diesem Hintergrund weckte die von Bundeskanzler Olaf Scholz am 27. Februar 2022 verkündete „Zeitenwende“ große Erwartungen. Sie schien als Paradigma für die postliberale Weltordnung geeignet, zumal der Kanzler sie kurz darauf zu einer „Global Zeitenwende“ ausbaute. Unglücklicherweise wird sie ihnen jedoch nicht gerecht. Die Herausforderung besteht nicht darin, eine künftige multipolare Weltordnung zu steuern und der EU darin einen der vorderen Plätze zu sichern. Das drängende Problem besteht vielmehr in dem sich entwickelnden weltumspannenden Systemkonflikt zwischen revisionistisch orientierten Autokratien und Demokratien, die eine regelbasierte internationale Ordnung aufrechterhalten wollen. Der historische Vergleich mit der Zwanzigjährigen Krise von 1919 bis 1939 legt nahe, dass es dazu eines „demokratischen Antirevisionismus“ bedarf.
Zermürbung durch Mehrfrontendruck: Wie die Achse der Autokratien die westliche Allianz in die Knie zwingen will
Authors: Herold Heiko 
Published: June 2024

Zusammenfassung
In den vergangenen Jahren hat sich eine Achse der Autokratien gebildet, die alles daransetzt, die liberale Weltordnung sukzessive zu unterminieren und sie zu zerstören. Die treibenden Kräfte sind Russland, China, der Iran und Nordkorea. Bei der Achse der Autokratien handelt es sich nicht um ein formelles Bündnis, sondern um eine Zweckgemeinschaft autoritär regierter Staaten, die mit der globalen Hegemonialmacht USA ein gemeinsames Feindbild haben, eine revisionistische Außenpolitik betreiben und die Weltordnung in ihrem Sinne umgestalten wollen. Dieser Beitrag befasst sich mit der Strategie Russlands und seiner Verbündeten, auf allen Kontinenten Konflikte koordiniert und opportunistisch zu eskalieren, um die westlichen Staaten, allen voran die USA, durch Mehrfrontendruck globalpolitisch zu überfordern und strategisch zu schwächen. Offenbar scheinen die Strategen in Moskau darauf zu setzen, dass die westliche Aufmerksamkeit und Unterstützung für die Ukraine nachlassen wird, sobald der Westen nicht mehr in der Lage sein wird, die multiplen Krisen, Konflikte und Kriege, die von der Achse der Autokratien geschürt werden, in den Griff zu bekommen. Der Beitrag widmet sich sowohl den globalen Brennpunkten, die in den zurückliegenden Monaten im Rahmen dieser Strategie angeheizt wurden, als auch jenen, die schon bald angeheizt werden könnten.
Unusual behavior in thermodynamical properties of chitosan-lanthanide oxide composites: competition between the size and mass
Authors: Jesuraj Kabiriyel , Ramasamy Jeyanthi , Jeyabal Sophia , Samu Shahabuddin Naina Mohammed , Amalraj Jacquline Regina Mary , Pandian Karthikeyan Manimozhi , Karuppasamy Radhidevi , Thangarajan Sarveswaran , Chinnan Raja Mohan 
Published: June 2024

Abstract
The objective of this investigation is to explore how doping chitosan (Chi) with different lanthanide oxides (LnO) such as cerium, neodymium, samarium, europium, gadolinium, dysprosium, and holmium oxides affects its thermodynamic properties. Especially the effect of lanthanide contraction which is the competition between mass and size has been investigated and reported. The investigation describes a method for calculating various physical properties of a Chi-LnO composite material based on experimental values of refractive index, density, viscosity, and ultrasonic velocity concerning the mass and size of the LnO doped with chitosan. These properties play crucial roles in understanding the behavior and characteristics of composite materials. The process involves deriving the physical properties such as dielectric constant, intermolecular free path length, relaxation time, ultrasonic attenuation, relative association, surface tension, Gibbs free energy and non-linearity parameters are calculated from the experimental value of the refractive index, density, viscosity and ultrasonic velocity properties from the given experimental data and results are discussed in a detailed manner.
Estrategia sostenible para mejorar la eficiencia de los servicios de inseminación artificial en ganado bovino en el trópico
Authors: Pedroso Sosa Rodolfo , Roller Gutiérrez Felicia , Burgos Macías Daniel Isaías 
Published: June 2024

The aim of this study was to evaluate the efficiency of artificial insemination (AI) services in Holstein x Brahman cows under a heat induction programme. Three experiments were carried out. In Exp. 1, a retrospective analysis of the efficiency of AI insemination of 41 000 cows treated with the combination of progesterone and oestradiol benzoate or equine chorionic gonadotropin (eCG) was carried out. In Exp. 2 it was evaluated 863 cows inseminated after heat induced with progesterone and oestradiol benzoate to know the physiological events that occur before and after service in herds with a high incidence of anoestrus. Gynaecological examinations and determination of progesterone in milk were performed. The purpose of Exp. 3 was to improve the effectiveness of AI services for cows in postpartum anoestrus treated with progesterone and oestradiol benzoate combined with a technique to identify and induce the return to service of females that did not conceive. Only 30% of the cows exceeded 40% conception. The best results were obtained when using eCG (47% vs 29%). The problems associated with the low conception rate were unfertilized oestrus, embryonic mortality and anoestrus after breeding (Exp. 2). The return to service induction technique increased (p<0.001) the conception rate of the second induced service and the percentage of accumulated pregnancy in the treated group compared to the control (69.0 and 32.0%, respectively) (Exp. 3).
Ethnicity and Representation
Authors: Ament-Kovács Bence 
Published: June 2024

AbstractThose Germans who remained in Hungary after the Second World War faced complex political, economic, and social difficulties. In cultural terms, the diverse self-definitions of the Germans living in Hungary at that time precluded national cohesion, despite the use by the authorities of the unifying definition “German.” This national minority was bound together primarily by shared trauma. Individuals and communities alike were searching for their place amidst the changed circumstances, and it was the umbrella organization known as the Democratic Association of Germans in Hungary (Magyarországi Németek Demokratikus Szövetsége) that sought to bring them together. It was not until the 1970s that the association began to professionalize its activities and to conduct ethnographic research in cooperation with qualified specialists. During this process, the village of Harta, which was already famous for its folk art, came to their attention. It was specifically the economic potential of this settlement in Bács-Kiskun County, and its character as an ethnic and confessional enclave, that laid the foundations for the uniform objects and motifs of this local center of furniture painting. After the Second World War, the county administration's cultural policy was relatively accepting of the furniture-making tradition here, and the local intelligentsia showed a supportive attitude towards the settlement's German heritage. In the 1970s, there was still a furniture painter living in Harta, who won the most prestigious folk-art award, regularly participated in exhibitions and gala events, and even produced painted furniture in the cooperative's subsidiary branch at the initiative of the local council president. This ensured that painted furniture from Harta came to represent not only the traditionalist aspirations of the German Association, but also national cultural policy. Harta furniture emerged as the most iconic style of minority painted furniture and as the shared heritage of the German community in Hungary.
Enrichment of apple juice with antioxidant-rich elderberry (Sambucus nigra L) pomace extract
Authors: Furulyás D. , Szalóki-Dorkó L. , Máté M. , Stefanovits-Bányai É. 
Published: June 2024

AbstractElderberry pomace, a by-product generated by elderberry processing industries, may be a favourable resource for further utilisation due to its components of high nutritional quality. In our research, elderberry pomace extract (EP) was added to apple juice as natural food additive for controlling microbial spoilage and enriching antioxidant components.During the 8-week storage period of enriched apple juice (EPA) and control apple juice samples antioxidant properties were evaluated using the FRAP assay, Folin–Ciocalteu method, and pH differentiation method. The amount of polyphenols components was quantified using an RP-HPLC method. The microbiological status of samples was studied by determining the total viable and yeast/mould counts. The EPA is an important source of polyphenol components and other bioactive compounds, and the results suggest that extract of elderberry pomace could be a promising natural preservative to improve microbiological stability during refrigerated storage and increase the quality of apple juice.
A child with congenital hypothyroidism posted for emergency surgery- anaesthesia challenges
Authors: Paul Anju , Hiwarkar Amit , Patil Madhuri , Tonapi Kshitija Dipak 
Published: June 2024

Paediatric cases pose considerable anaesthetic challenges and are more challenging if they are posted for emergency surgeries with associated comorbidities like congenital hypothyroidism. Few reported cases of anaesthesia management of congenital hypothyroid cases are there in the literature. Challenges are due to the difficult airway, associated congenital anomalies and increased sensitivity to anaesthetic drugs. Knowledge of pathophysiology, preoperative optimization and proper selection and planning of anaesthesia techniques are essential for successful anaesthesia management of children with congenital hypothyroidism for emergency surgeries. Congenital hypothyroidism in a child poses significant challenges for anaesthesiologists because of altered physiology, airway anatomy and difficult airway and drug metabolism.