bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appropriate Sampling and Longer Follow-Up Are Required to Rigorously Evaluate Longevity of Humoral Memory After Vaccination
Authors: Ganusov Vitaly V 
Published: June 2024

Abstract
One of the goals of vaccination is to induce long-lived immunity against the infection and/or disease. Many studies have followed the generation of humoral immunity to SARS-CoV-2 after vaccination; however, such studies typically varied by the duration of the follow-up and the number of time points at which immune response measurements were done. How these parameters (the number of time points and the overall duration of the follow-up) impact estimates of immunity longevity remain largely unknown. Several studies, including one by Arunachalam et al. (2023. J. Clin. Invest. 133: e167955), evaluated the humoral immune response in individuals receiving either a third or fourth dose of mRNA COVID-19 vaccine; by measuring Ab levels at three time points (prior to vaccination and at 1 and 6 mo), Arunachalam et al. found similar half-life times for serum Abs in the two groups and thus suggested that additional boosting is unnecessary to prolong immunity to SARS-CoV-2. I demonstrate that measuring Ab levels at these three time points and only for 6 mo does not allow one to accurately evaluate the long-term half-life of vaccine-induced Abs. By using the data from a cohort of blood donors followed for several years, I show that after revaccination with vaccinia virus, vaccinia virus–specific Abs decay biphasically, and even the late decay rate exceeds the true slow loss rate of humoral memory observed years prior to the boosting. Mathematical models of Ab response kinetics, parameterized using preliminary data, should be used for power analysis to determine the most appropriate timing and duration of sampling to rigorously determine the duration of humoral immunity after vaccination.
Spherical objects, transitivity and auto-equivalences of Kodaira cycles via gentle algebras
Authors: Opper Sebastian 
Published: June 2024

This paper studies the class of spherical objects over any Kodaira

n

-cycle of projective lines and provides a parametrization of their isomorphism classes in terms of closed curves on the

n

-punctured torus without self-intersections. Employing recent results on gentle algebras, we derive a topological model for the bounded derived category of any Kodaira cycle. The groups of triangle auto-equivalences of these categories are computed and are shown to act transitively on isomorphism classes of spherical objects. This answers a question by Polishchuk (2002) and extends earlier results by Burban–Kreußler (2012) and Lekili–Polishchuk (2019). The description of auto-equivalences is further used to establish faithfulness of a mapping class group action defined by Sibilla (2014). The final part describes the closed curves which correspond to vector bundles and simple vector bundles. This leads to an alternative proof of a result by Bodnarchuk–Drozd–Greuel (2012) which states that simple vector bundles on cycles of projective lines are uniquely determined by their multi-degree, rank and determinant. As a by-product, we obtain a closed formula for the cyclic sequence of any simple vector bundle on

C_{n}

as introduced by Burban–Drozd–Greuel (2001).
religião Cristocêntrica como possibilidade de reconciliação diante do divertissement em Blaise Pascal
Authors: Silva Martins Breno 
Published: June 2024

O presente artigo pretende mostrar uma possibilidade de reconciliação do homem diante de suas insuficiências e misérias, isto é, diante do divertissement. O caminho antropológico, indicado pela antropologia pascaliana, traz à luz um homem paradoxal e desproporcional à natureza, tanto à sua mesma quanto à natureza como mundo físico que se percebe decaído de um primeiro estado sobrenatural de comunhão com Deus. Neste sentido, a vida cristã transmite ao homem um desprezar-se para amar o Cristo Mediador, o Deus que o homem consegue se aproximar porque foi o Deus que assumiu as misérias e os paradoxos humanos e, por isso, o homem não se desespera.
8-Step Method for Third Order Fredholm Integro-Differential Equations with Vieta-Pell-Lucas as Approximating Function.
Authors: Olayemi K.S. , Obayomi A.A. , Ogunrinde R. B. 
Published: June 2024

Purpose: In this paper, we derive multistep numerical methods for third order linear Fredholm integro-differential equation using Vieta-Pell-Lucas polynomial as approximating function.
Methodology: These new method is implemented by embedding it with Trapezoidal, Booles and Simpson 1/3 numerical methods. The derivation led to a block of twenty-four discrete schemes which simultaneously solves the third order linear integro-differential equation. The qualitative properties of the schemes have been investigated.
Findings: The analysis of the method reveals that the proposed method is of order seven and the method is found to be consistent and stable, hence convergent.
Unique contributor to theory, policy and practice: Numerical experiments have been performed on some selected problems and the results show that the proposed method perform creditably well when compared with the exact solution of the selected examples
Lifestyle changes and Nutrition in Polycystic Ovarian Disorder: A Holistic Review
Authors: Tiwari Archita , Verma Arti , Mishra Shrishti , Mishra Bharat 
Published: June 2024

Polycystic Ovarian Disorder (PCOD) is a prevalent endocrine illness in women of reproductive age which is a reproductive and metabolic disorder. It shows hormonal abnormalities in which there is an excessive production of androgens and that is one of the main causes of infertility, diabetes, irregular menstrual periods, hirsutism, hair loss, obesity and acne. One of the main features of PCOD is the presence of cysts on the ovaries, which can affect their ability to release eggs regularly and Anti-Müllerian hormone (AMH) plays an inhibitory role in follicular development and recruitment, contributing to follicular arrest. AMH inhibitory action on FSH-induced aromatase production likely contributes to hyperandrogenism in PCOD. Some factors which can cause of PCOD such as lack of exercise, skipping breakfast, fast food, unbalanced sleep, obesity, genetic, environmental factors and stress level. Lifestyle and nutrition can affect PCOD development and maintenance in PCOD can be done by lifestyle changes such as diet regulation (in taking of vitamins, antioxidant and Creatine) and exercise, as well as medications to regulate hormones, improve fertility and sleep which play a vital role in PCOD management.
Эффективное использование сказок на уроках английского языка в общеобразовательной школе
Authors: Абдыханова Б.А. , Мұрат Н.М. 
Published: June 2024

Основной из задач преподавания является результативность обучения. Данная цель достигается благодаря постоянному развитию навыков, внедрению современных методов преподавания и введению интегрированных технологий в процесс урока. В данной статье рассматривается нетрадиционный формат обучения, помогающий ученикам быстрее усваивать новую информацию и применять ее в жизни. В ходе написания статьи была определена роль фольклорного жанра – сказок, как методического средства для эффективного развития способностей учеников по английскому языку. Сказка активизирует мыслительную деятельность школьников, превращает процесс обучение в интересное путешествие в волшебный мир, где они могут проживать героев, что влияет на стимул изучения языка. Также, была проделана исследовательская работа в качестве онлайн-анкетирования как среди учителей, так и среди учеников об их представлении и мнении об эффективности и частоте использовании сказок на уроках английского языка. Это дало понять, что сказки обладают значительным потенциалом для обогащения изучения английского языка, особенно в плане расширения словарного запаса и межкультурного понимания. К тому же, акцентируется внимание на практическом применении сказки и на методологических подходах в ходе обучения языку с применением дидактического материала в виде сказки «Красная шапочка».
The primary objective of pedagogy is the effectiveness of acquisition. This goal is accomplished through the continuous development of skills, the introduction of modern teaching methods, and the integration of sophisticated technologies into the didactic process. This manuscript considers a non-traditional paradigm of pedagogy that contributes to the accelerated assimilation of new information and its practical application. During the composition of this manuscript, the role of the folklore genre - fairy tales - as a methodological instrument for the effective development of students' abilities in the English language was ascertained. A fairy tale activates the cognitive activity of pupils, and transforms the learning process into a captivating journey, into a fantastical realm where they can embody the characters, thereby affecting the stimulus of language learning. Additionally, empirical research was conducted in the form of an online questionnaire among both educators and students regarding their perceptions and perspectives on the effectiveness and frequency of utilizing fairy tales in English lessons. This made it clear that fairy tales have significant potential to enrich English language learning, especially in terms of vocabulary expansion and cross-cultural comprehension. Furthermore, the practical implementation of fairy tales and methodological approaches during language teaching with the didactic material based on the fairy tale "Little Red Riding Hood" are emphasized.
Quality and competitiveness are the main priorities
Authors: Адильбаева А.С. 
Published: June 2024

Изначально перед высшим учебным заведением была поставлена цель подготовки высококвалифицированных специалистов, конкурентоспособных на региональном, страновом и мировом уровнях. Отмечается, что в современном мире высшее образование является важнейшим приоритетом и одной из целей устойчивого развития, что подтверждается документами ООН и ЮНЕСКО, признающими его важнейшую роль в социально-экономическом развитии всех стран мира. В связи с этим в статье анализируются роль Alikhan Bokeikhan University в системе образования Республики Казахстан, его организационная, учебная, научная деятельность. Значительное внимание уделено повышению качества образования, улучшению материально-технической базы, квалификации научно-педагогического состава, расширению международного сотрудничества, перспективам развития университета и росту его вклада в региональную экономику, социальную сферу.
The University’s anniversary is not only a joyful event, but also a time to sum up its activities. Initially, the higher education institution set the goal of training highly qualified specialists who would be competitive at the regional, national and global levels. It is noted that in the modern world, higher education is the most important priority and one of the goals of sustainable development, which is confirmed by UN and UNESCO documents recognizing its critical role in the socio-economic development of all countries of the world. In this regard, the article analyzes the role of the Alikhan Bokeikhan University in the education system of the Republic of Kazakhstan, its organizational, educational, and scientific activities. Considerable attention is paid to improving the quality of education, improving the material and technical base, qualifications of scientific and teaching staff, expanding international cooperation, prospects for the development of the university and the growth of its contribution to the regional economic system.
The concept of the methodology for analyzing the efficiency of using the company's own capital
Authors: Курманбаева С.Т. , Рамазанова К.Б. 
Published: June 2024

В данной статье рассматривается использование собственного капитала как источника финансирования ограничено, поскольку зависит от дивидендной политики распределения чистой прибыли. Экономический анализ структуры собственного капитала и других источников финансирования позволяет установить резервы повышения финансовой устойчивости, которые необходимы для разработки финансовой стратегии и обоснования основных направлений экономической политики управления капиталом коммерческой организации, а также осуществить корректировку управленческих решений по оптимальному соотношению заемного и собственного капиталов, снизить уровень финансового риска.
This article considers the use of equity as a source of financing is limited, since it depends on the dividend policy of distribution of net profit. An economic analysis of the structure of equity and other sources of financing makes it possible to establish reserves for improving financial stability, which are necessary to develop a financial strategy and substantiate the main directions of the economic policy of capital management of a commercial organization, as well as to adjust management decisions on the optimal ratio of debt and equity, reduce the level of financial risk. Keywords: capital, efficiency, accounting, concentration
Corruption: prerequisites and features of prevention
Authors: Аймханова Г.К. , Ногаева Н.М. 
Published: June 2024

Одной из актуальных проблем является профилактика коррупции и ее предпосылки. Наряду с опытом передовых государств в борьбе с коррупцией большое значение имеют международные отношения. В статье предлагается работа, которая должна сопровождаться работой, проводимой в направлении коррупции.
Сыбайлас жемқорлықтың алдын-алу және оның алғы шарттары өзекті мәселелерінің бірі болып табылады. Сыбайлас жемқорлықпен күресуде алдыңғы қатардағы мемлекеттер тәжірибесімен қатар халықаралық қатынастардың да маңызы зор. Мақалада сыбайлас жемқорлықтың алдың алу бағытында атқарылып жатқан жұмыстармен қатар атқарылу керек жұмыстар ұсынылады.
One of the urgent problems is the prevention of corruption and its prerequisites. Along with the experience of advanced States in the fight against corruption, international relations are of great importance. The article suggests work that should be accompanied by work carried out in the direction of corruption.
Historical aspects of the development of the concept of strategic enterprise management
Authors: Шустова Е.П. , Гэ Ч. 
Published: June 2024

В данной статье рассматриваются исторические аспекты развития концепции стратегического управления компанией, основные этапы развития стратегического управления, а также матрица стратегического управления.
This article considers historical aspects of the development of the concept of strategic management of the company, the main stages of the development of strategic management, as well as the matrix of strategic management.
Strategi Pembinaan Disiplin Siswa di Madrasah Aliyah Negeri (MAN) 1 Medan
Authors: Dewi Yuliana 
Published: June 2024

Mengingat kegiatan pembinaan sikap disiplin siswa bukan merupakan pekerjaan yang mudah dibutuhkan strategi khusus dalam upaya pelaksanaan kegiatan tersebut. Madrasah Aliyah Negeri (MAN) 1 Medan adalah salah satu Madrasah Negeri yang cukup terkenal di kota Medan, selain mempunyai letak yang strategis MAN 1 Medan juga banyak melahirkan SDM yang berkualitas. Hal ini terlihat dari banyaknya alumni MAN 1 Medan yang sukses berkarir, baik dalam dunia pendidikan maupun non pendidikan. Siswa-siswi lulusan MAN 1 Medan juga banyak yang melanjutkan studi kejenjang perguruan tinggi dalam dan luar negeri. Siswa-siswi tampak menikmati ketenangan dan kenyamanan belajar di Madrasah tersebut. Namun peneliti menemukan beberapa perilaku siswa yang tidak wajar, yang kemudian perilaku tersebut penulis cantumkan sebagai identifikasi maslah pada penelitian ini. Adapun identifikasi masalah pada penelitian ini yaitu: adanya siswa yang terlambat datang ke-MAN 1 Medan pada 3 hari berturut selama masa observasi awal dilakukan, adanya siswa MAN 1 Medan yang masih berada di area Madrasah sampai Menjelang Magrib dan adanya siswa-siswi yang makan ke kantin pada saat jam pelajaran olah raga. Mengingat MAN 1 Medan merupakan madrasah yang terkenal dan banyak diminati orang di kota Medan Sekitar, beberapa perilaku siswa di atas merupakan masalah yang dapat mungurangi keharuman nama MAN 1 Medan. Oleh karena itu, peneliti merasa hal ini perlu di teliti guna mendapat informasi akurat tentang pembinaan disiplin di MAN 1 Medan.
Investigating the effect of silicate- and calcium-based ocean alkalinity enhancement on diatom silicification
Authors: Ferderer Aaron , Schulz Kai G. , Riebesell Ulf , Baker Kirralee G. , Chase Zanna , Bach Lennart T. 
Published: June 2024

Abstract. Gigatonne-scale atmospheric carbon dioxide removal (CDR) will almost certainly be needed to supplement the emission reductions required to keep global warming between 1.5–2 °C. Ocean alkalinity enhancement (OAE) is an emerging marine CDR method with the addition of pulverised minerals to the surface ocean being one widely considered approach. A concern of this approach is the potential for dissolution products released from minerals to impact phytoplankton communities. We conducted an experiment with 10 pelagic mesocosms (M1–M10) in Raunefjorden, Bergen, Norway, to assess the implications of simulated silicate- and calcium-based mineral OAE on a coastal plankton community. Five mesocosms (M1, M3, M5, M7, and M9) were enriched with silicate (∼ 75 µmol L−1 Na2SiO3), alkalinity along a gradient from 0 to ∼ 600 µmol kg−1, and magnesium in proportion to alkalinity additions. The other five mesocosms (M2, M4, M6, M8, M10) were enriched with alkalinity along the same gradient and calcium in proportion to alkalinity additions. The experiment explored many components of the plankton community, from microbes to fish larvae, and here we report on the influence of simulated mineral based OAE on diatom silicification. Macronutrients (nitrate and phosphate) limited silicification at the onset of the experiment until nutrient additions on day 26. Silicification was significantly greater in the silicate-based mineral treatment, with all genera except Cylindrotheca displaying an increase in silicification as a result of the increased concentration of dissolved silicate. In contrast to the effect of differences in dissolved silicate concentrations between the two mineral treatments, increases in alkalinity only influenced the silicification of two genera, Pseudo-nitzschia and Nitzschia. The four other genera (Arcocellulus, Cylindrotheca, Skeletonema, and Thalassiosira) investigated here displayed no significant changes in silicification as a result of alkalinity increases between 0 and 600 µmol kg−1 above natural levels. In summary, our findings illustrate that the enhancement of alkalinity via simulated silicate- and calcium-based methods has limited genus-specific impacts on the silicification of diatoms. This research underscores the importance of understanding the full breadth of different OAE approaches, their risks, co-benefits, and potential for interactive effects.
Desulfurization of Basra Diesel Fuel by Emulsification – Adsorption Processes
Authors: Khudhur Ali G. , Hantosh Ahmed A. , Omer Mohammed A. 
Published: June 2024

In this study, the combined emulsification–adsorption processes were employed for the desulfurization of Basra diesel fuel. A high sulfur diesel fuel of 1.4538 wt% from the Basra refinery was oxidized effectively with H2O2 and Acetic acid (AcOH) as a catalyst to reduce sulfur content to 1.0875 wt% before being emulsified. The emulsification desulfurization (EDS) process using Alkyl benzene sulfonate (ABS) as a surfactant was optimized by 20 trails according to Response Surface Methodology (RSM). A 0.83886 wt% was achieved at the following optimum conditions: Surfactant concentration 20 wt.%, temperature 57.56 ᵒC, and homogenization speed 5695 rpm. The adsorptive desulfurization (ADS) process using activated bentonite clay was carried out in a batch system. The RSM was applied to determine the effect of contact time (1-10 hr), clay mass (5- 20 gm/50ml), and temperature (30-100 ᵒC) on the sulfur removal. Results showed that the sulfur content of 0.57 wt% was achieved at the following conditions: adsorption time 7.18 hrs., temperature 53.3 ᵒC, and clay mass 15.24 gm/ 50ml. The achieved sulfur removal efficiency was 23% and 32% for EDS and ADS respectively. The diesel fuel quality was studied by GC and IREX.
Envelhecimento e qualidade de vida
Authors: Sousa Miriam Prudenciano de , Kamimura Quésia Postigo , Oliveira Adriana Leonidas de , Cornetta Vitória Kedy , Postigo Sóstenes , Cerveny Ceneide Maria de Oliveira 
Published: June 2024

O presente estudo teve como objetivo identificar e analisar a qualidade de vida de idosos na cidade do interior do Estado e São Paulo, Caçapava, Brasil. Foi composta uma amostra probabilística, com 107 pessoas com 60 e mais anos. Quanto aos instrumentos para coleta de dados foram utilizados o WHOLQOL bref e WHOQOL-OLD. Resultados revelaram que os idosos apresentam qualidade de vida geral média de 65,0 (±11,39). O domínio do WHOQOL-bref com maior valor médio foi Relações Sociais (77,7±17,08), seguido pelos domínios Meio Ambiente (68,61±15,41) e Psicológico (60,1±15,71), enquanto que o menor escore médio foi observado no domínio Físico (53,7±13,06). No instrumento WHOQOL-OLD a faceta Intimidade obteve uma das maiores pontuações, indicando uma boa capacidade dos idosos de ter relações pessoais e íntimas. As facetas Morte e morrer e Funcionamento do sensório apresentaram as mais baixas pontuações entre os idosos pesquisados. Frente aos resultados são discutidas as principais demandas de programas de promoção de qualidade de vida do idoso no contexto investigado.
Evaluation Of Crossing Vessel Operation Patterns On The Kariangau-Penajaj Port Kariangau East Kalimantan Province
Authors: Argo Junian Budi , Amanda Monica , Ulya Febriyanti Himmatul , Puspitasari Novrianti , Dewi Apriani Dahlia , Wulandari Devita Eka 
Published: June 2024

Kariangau Ferry Port is a port in Balikpapan City which serves the Kariangau-Penajam route with a total of 12 ships per day. Ship operations on this route are not balanced with minimum service standards for ship operations and the ideal number of trips so that when the ship sails it does not carry maximum passengers or vehicles. This research aims to increase the efficiency of ship use based on the current ideal number of ships and trips and minimum service standards for ship operations. The method used in this research is analysis load factor, analysis of minimum service standards for ship operations, analysis of ship needs, and scheduling analysis. Based on the results of the calculation analysis load factorobtained on averageload factorfor passengers it is currently 1% and for vehicles it is currently 57%. The change in ship operating patterns on the Kariangau-Penajam route now from existing conditions, which was obtained through the results of analysis of the calculation of the need for the number of ships and analysis of optimal ship schedules, has caused differences between the current ship operating patterns and the planned operation patterns resulting from the calculations. The operating pattern of this plan is calculated based on the number of trips and the number of ships according to the needs of service users so that ships on this route can carry maximum passengers and vehicles.load factorideal 65%.