bluuebunny/crossref_metadata_2025_split huggingface dataset:
The AP-3 β Adaptin Mediates the Biogenesis and Function of Lytic Vacuoles inArabidopsis
Authors: Feraru Elena , Paciorek Tomasz , Feraru Mugurel I. , Zwiewka Marta , De Groodt Ruth , De Rycke Riet , Kleine-Vehn Jürgen , Friml Jiří 
Published: August 2010

AbstractPlant vacuoles are essential multifunctional organelles largely distinct from similar organelles in other eukaryotes. Embryo protein storage vacuoles and the lytic vacuoles that perform a general degradation function are the best characterized, but little is known about the biogenesis and transition between these vacuolar types. Here, we designed a fluorescent marker–based forward genetic screen in Arabidopsis thaliana and identified a protein affected trafficking2 (pat2) mutant, whose lytic vacuoles display altered morphology and accumulation of proteins. Unlike other mutants affecting the vacuole, pat2 is specifically defective in the biogenesis, identity, and function of lytic vacuoles but shows normal sorting of proteins to storage vacuoles. PAT2 encodes a putative β-subunit of adaptor protein complex 3 (AP-3) that can partially complement the corresponding yeast mutant. Manipulations of the putative AP-3 β adaptin functions suggest a plant-specific role for the evolutionarily conserved AP-3 β in mediating lytic vacuole performance and transition of storage into the lytic vacuoles independently of the main prevacuolar compartment-based trafficking route.
TDIF Peptide Signaling Regulates Vascular Stem Cell Proliferation via theWOX4Homeobox Gene inArabidopsis
Authors: Hirakawa Yuki , Kondo Yuki , Fukuda Hiroo 
Published: August 2010

AbstractThe indeterminate nature of plant growth and development depends on the stem cell system found in meristems. The Arabidopsis thaliana vascular meristem includes procambium and cambium. In these tissues, cell–cell signaling, mediated by a ligand-receptor pair made of the TDIF (for tracheary element differentiation inhibitory factor) peptide and the TDR/PXY (for TDIF RECEPTOR/ PHLOEM INTERCALATED WITH XYLEM) membrane protein kinase, promotes proliferation of procambial cells and suppresses their xylem differentiation. Here, we report that a WUSCHEL-related HOMEOBOX gene, WOX4, is a key target of the TDIF signaling pathway. WOX4 is expressed preferentially in the procambium and cambium, and its expression level was upregulated upon application of TDIF in a TDR-dependent manner. Genetic analyses showed that WOX4 is required for promoting the proliferation of procambial/cambial stem cells but not for repressing their commitment to xylem differentiation in response to the TDIF signal. Thus, at least two intracellular signaling pathways that diverge after TDIF recognition by TDR might regulate independently the behavior of vascular stem cells. Detailed observations in loss-of-function mutants revealed that TDIF-TDR-WOX4 signaling plays a crucial role in the maintenance of the vascular meristem organization during secondary growth.
TheUstilago maydisClp1 Protein Orchestrates Pheromone andb-Dependent Signaling Pathways to Coordinate the Cell Cycle and Pathogenic Development
Authors: Heimel Kai , Scherer Mario , Schuler David , Kämper Jörg 
Published: August 2010

AbstractRegulation of the cell cycle and morphogenetic switching during pathogenic and sexual development in Ustilago maydis is orchestrated by a concerted action of the a and b mating-type loci. Activation of either mating-type locus triggers the G2 cell cycle arrest that is a prerequisite for the formation of the infectious dikaryon; this cell cycle arrest is released only after penetration of the host plant. Here, we show that bW, one of the two homeodomain transcription factors encoded by the b mating-type locus, and the zinc-finger transcription factor Rbf1, a master regulator for pathogenic development, interact with Clp1 (clampless 1), a protein required for the distribution of nuclei during cell division of the dikaryon. In addition, we identify Cib1, a previously undiscovered bZIP transcription factor required for pathogenic development, as a Clp1-interacting protein. Clp1 interaction with bW blocks b-dependent functions, such as the b-dependent G2 cell cycle arrest and dimorphic switching. The interaction of Clp1 with Rbf1 results in the repression of the a-dependent pheromone pathway, conjugation tube formation, and the a-induced G2 cell cycle arrest. The concerted interaction of Clp1 with Rbf1 and bW coordinates a- and b-dependent cell cycle control and ensures cell cycle release and progression at the onset of biotrophic development.
The fall and rise of knowledge organization: new dimensions of subject description and retrieval
Authors: Broughton Vanda 
Published: August 2010

PurposeThe purpose of this editorial is to introduce the selected Proceedings of the 1st National Conference of ISKO UK, the UK Chapter of the International Society for Knowledge Organization. It aims to provide some background for the group, and place it within the context of the recent history of information organization and retrieval in subject domains.Design/methodology/approachThe paper introduces a selection of papers delivered at the 1st National Conference of the UK Chapter of the International Society for Knowledge Organization.FindingsThe field of knowledge organization is lively and progressive, and researchers and practitioners in many sectors are actively engaged with it, despite its apparent decline in LIS education. New communities of interest may use different terms to describe this work, but there is much common ground, and a growing convergence of ideas and methods.Originality/valueThe value of existing theory is now more widely recognised, and the importance of structured knowledge organization systems and vocabularies in retrieval is generally acknowledged. It is to be hoped that these important areas of information practice and research will soon be restored to their former place in professional education.
Lessons learned in content architecture harmonization and metadata models
Authors: Wagger Shana , Park Randi , Dowding Bedford Denise Ann 
Published: August 2010

PurposeThis paper aims to review key content, architecture, and metadata model decisions and strategies in creation of a publication portal (on DVD to start), based on a 30+ year series of flagship reports from the World Bank.Design/methodology/approachThe paper describes and analyzes key considerations and aspects of the project, including content architecture, content analysis, DTD selection, retrospective conversion, vendor management, design of metadata architectures, use of automated profiling methods, user‐information behavior, and search architectures supporting complex content architectures. It includes the challenges of applying an institutionally based taxonomy required to express subject‐matter responsibilities and relationships within the World Bank.FindingsThe team learned that the metadata behavior and architecture (inheritance, relationships, variations) are more complex than simple links between parent and child objects. The project also reinforced the importance of comprehensive and dynamic topic taxonomy for classifying content that is both historical and current. The approach to defining classes for each full report (parent) will be likely to change, given what has been learned. The team would recommend that parts be classified and the sum of the part classes be assigned to the whole report. As a result of this exploratory work, the Bank's approach to classification and indexing of report series is changing from a top‐down to a bottom‐up inheritance.Originality/valueThe study provides insights into both general and World Bank‐specific challenges in creating a publication portal and derives some best practices for content architecture, metadata architecture, and use of automated profiling methods.
“Content architecture”
Authors: Boteram Felix 
Published: August 2010

PurposeThis paper seeks to develop a specified typology of various levels of semantic interoperability, designed to provide semantically expressive and functional means to interconnect typologically different sub‐systems in an international comprehensive knowledge organization system, supporting advanced information retrieval and exploration strategies.Design/methodology/approachTaking the analysis of rudimentary forms of a functional interoperability based on simple pattern matching as a starting‐point, more refined strategies to provide semantic interoperability, which is actually reaching the conceptual and even thematic level, are being developed. The paper also examines the potential benefits and perspectives of the selective transfer of modelling strategies from the field of semantic technologies for the refinement of relational structures of inter‐system and inter‐concept relations as a requirement for expressive and functional indexing languages supporting advanced types of semantic interoperability.FindingsAs the principles and strategies of advanced information retrieval systems largely depend on semantic information, new concepts and strategies to achieve semantic interoperability have to be developed.Research limitations/implicationsThe approach has been developed in the functional and structural context of an international comprehensive system integrating several heterogeneous knowledge organization systems and indexing languages by interconnecting them to a central conceptual structure operating as a spine in an overall system designed to support retrieval and exploration of bibliographic records representing complex conceptual entities.Originality/valueResearch and development aimed at providing technical and structural interoperability has to be complemented by a thorough and precise reflection and definition of various degrees and types of interoperability on the semantic level as well. The approach specifies these levels and reflects the implications and their potential for advanced strategies of retrieval and exploration.
Large‐scale grid computing for content‐based image retrieval
Authors: Town Chris , Harrison Karl 
Published: August 2010

PurposeContent‐based image retrieval (CBIR) technologies offer many advantages over purely text‐based image search. However, one of the drawbacks associated with CBIR is the increased computational cost arising from tasks such as image processing, feature extraction, image classification, and object detection and recognition. Consequently CBIR systems have suffered from a lack of scalability, which has greatly hampered their adoption for real‐world public and commercial image search. At the same time, paradigms for large‐scale heterogeneous distributed computing such as grid computing, cloud computing, and utility‐based computing are gaining traction as a way of providing more scalable and efficient solutions to large‐scale computing tasks.Design/methodology/approachThis paper presents an approach in which a large distributed processing grid has been used to apply a range of CBIR methods to a substantial number of images. By massively distributing the required computational task across thousands of grid nodes, very high through‐put has been achieved at relatively low overheads.FindingsThis has allowed one to analyse and index about 25 million high resolution images thus far, while using just two servers for storage and job submission. The CBIR system was developed by Imense Ltd and is based on automated analysis and recognition of image content using a semantic ontology. It features a range of image‐processing and analysis modules, including image segmentation, region classification, scene analysis, object detection, and face recognition methods.Originality/valueIn the case of content‐based image analysis, the primary performance criterion is the overall through‐put achieved by the system in terms of the number of images that can be processed over a given time frame, irrespective of the time taken to process any given image. As such, grid processing has great potential for massively parallel content‐based image retrieval and other tasks with similar performance requirements.
An evaluation of enhancing social tagging with a knowledge organization system
Authors: Matthews Brian , Jones Catherine , Puzoń Bartłomiej , Moon Jim , Tudhope Douglas , Golub Koraljka , Lykke Nielsen Marianne 
Published: August 2010

PurposeTraditional subject indexing and classification are considered infeasible in many digital collections. This paper seeks to investigate ways of enhancing social tagging via knowledge organization systems, with a view to improving the quality of tags for increased information discovery and retrieval performance.Design/methodology/approachEnhanced tagging interfaces were developed for exemplar online repositories, and trials were undertaken with author and reader groups to evaluate the effectiveness of tagging augmented with control vocabulary for subject indexing of papers in online repositories.FindingsThe results showed that using a knowledge organisation system to augment tagging does appear to increase the effectiveness of non‐specialist users (that is, without information science training) in subject indexing.Research limitations/implicationsWhile limited by the size and scope of the trials undertaken, these results do point to the usefulness of a mixed approach in supporting the subject indexing of online resources.Originality/valueThe value of this work is as a guide to future developments in the practical support for resource indexing in online repositories.
Biodiversity information retrieval across networked data sets
Authors: Sarinder K.K.S. , Lim L.H.S. , Merican A.F. , Dimyati K. 
Published: August 2010

PurposeBiodiversity resources are inevitably digital and stored in a wide variety of formats by researchers or stakeholders. In Malaysia, although digitizing biodiversity data has long been stressed, the interoperability of the biodiversity data is still an issue that requires attention. This is because, when data are shared, the question of copyright occurs, creating a setback among researchers wanting to promote or share data through online presentations. To solve this, the aim is to present an approach to integrate data through wrapping of datasets stored in relational databases located on networked platforms.Design/methodology/approachThe approach uses tools such as XML, PHP, ASP and HTML to integrate distributed databases in heterogeneous formats. Five current database integration systems were reviewed and all of them have common attributes such as query‐oriented, using a mediator‐based approach and integrating a structured data model. These common attributes were also adopted in the proposed solution. Distributed Generic Information Retrieval (DiGIR) was used as a model in designing the proposed solution.FindingsA new database integration system was developed, which is user‐friendly and simple with common attributes found in current integration systems.Originality/valueThe proposed system is unique in that it allows biodiversity data sharing, through the integration of biodiversity databases, hence enabling scientists to share information and generate knowledge. It also solves copyright problems by suggesting distributed warehouses, giving data owners the benefit of having their database under their own jurisdiction. It meets the requirements of querying heterogeneous and remote biodiversity databases.
Longitudinal roughness effect on magnetic fluid‐based squeeze film between conical plates
Authors: Indubhai Andharia Paresh , Deheri Gunamani 
Published: August 2010

PurposeThe paper aims to improve upon the performance of a squeeze film formed by a magnetic fluid between longitudinally rough conical plates.Design/methodology/approachThe objectives are achieved by mathematically modeling a magnetic fluid‐based squeeze film between longitudinally rough conical plates. The roughness of the bearing surface is modeled by a stochastic random variable with non‐zero mean, variance and skewness. The standard approach is to solve associated Reynold's equation which is stochastically averaged with respect to the random roughness parameter. The scope of this paper is the industrial applications with regard to enhanced performance of the bearing system.FindingsThe findings indicate that the performance of the bearing gets enhanced due to negatively skewed roughness. It is also noticed that the standard deviation increases the load carrying capacity which is unlike the case of transverse surface roughness. Further, this paper suggests that there exist considerable scopes for enhancing the performance of the longitudinally rough bearing system by choosing a suitable combination of the magnetization parameter and the semi‐vertical angle of the cone.Practical implicationsFrom the industry point of view, this investigation will be certainly useful for improving the performance of a magnetic fluid‐based squeeze film between longitudinally rough conical plates.Originality/valueThe paper presents the improved performance of a squeeze film formed by a magnetic fluid between longitudinally rough conical plates and thereby extending the life period of the bearing system.
Tribological properties of water‐soluble TiO2 nanoparticles as additives in water
Authors: Wang Jianhua , Li Jinlong , Wang Xiaobo , Liu Weimin 
Published: August 2010

PurposeThe purpose of this paper is to prepare water‐soluble TiO2 nanoparticles and evaluate the tribological properties as additives in water.Design/methodology/approachNanoparticles present excellent friction‐reducing and antiwear properties as additives in base oils. However, there are seldom literatures about the nanoparticles as additives in water as yet. In this work, water‐soluble TiO2 nanoparticles were prepared by sol‐gel method and characterized with transmission electron microscopy and selected area electron diffraction. The tribological properties as additives in water were investigated by SRV and the surface analysis by scanning electron microscope and X‐ray photon electron spectroscope.FindingsTiO2 nanoparticles modified with polyethylene glycol have uniform size about 10 nm and easily dissolve in water. The tribological experiments showed TiO2 nanoparticles exhibit excellent friction‐reducing and antiwear properties.Research limitations/implicationsThe paper is restricted to only TiO2 nanoparticles. Some other water‐soluble nanoparticles also should be prepared and their tribological properties investigated.Practical implicationsWater‐soluble TiO2 nanoparticles could be used as water additives and improve the tribological properties.Originality/valueThis paper emphasises that the water‐soluble nanoparticles are prepared and could be used as water additives.
Foresight in static stiffness of hydrostatic bearings with various compensations by film gradient versus recess pressure
Authors: Kang Yuan , Chen Cheng‐Hsien , Lee Jian‐Lin , Chen Juhn‐Horng , Chang Yeon‐Pun 
Published: August 2010

PurposeThe purpose of this paper is to investigate the static stiffness of hydrostatic bearings with three constant compensations in types of constant‐flow pump, capillary and orifice, and both single‐action and double‐action variable restrictors with cylindrical‐spool, tapered‐spool, and membrane types by film gradient and recess pressure.Design/methodology/approachThis paper utilizes the equations of flow equilibrium to determine the variations of film thickness or displacement of loading table with respect to the varying of recess pressure. For a hydrostatic bearing whose recess pressures are controlled by compensations, the stiffness characteristics can be presented directly by these variations.FindingsThe usage range of recess pressure and compensation parameters should be selected to correspond to a variation with smallest gradient.Originality/valueThis paper proposes an extensive database as a critical requirement for the selection of types and parameters of the compensation as to yield the acceptable or optimized characteristics in design of hydrostatic bearings.
Predicting turnover intentions
Authors: Perryer Chris , Jordan Catherine , Firns Ian , Travaglione Antonio 
Published: August 2010

PurposeThe purpose of this paper is to examine the relationship between organizational commitment, perceived organizational support (POS) and turnover intentions. The objective is to identify practical as well as theoretical implications of the relationships.Design/methodology/approachThis research was undertaken via a questionnaire in a large Australian public sector organization.FindingsThe interaction between POS and organizational commitment was a significant predictor of turnover intention. Employees with low levels of commitment, but high levels of support from the organization, are less likely to leave the organization.Research limitations/implicationsThis is a cross‐sectional study, using self‐reports for independent and dependent variables.Practical implicationsAs POS was found to influence turnover, this provides an avenue of approach for managers struggling to retain valuable employees whose commitment alone may not be enough to prevent them from leaving.Originality/valueThe paper examines the impact of POS, a neglected variable in the study of turnover intention, and in particular in its interactive effect between commitment and turnover.
The performance impact of business process standardization: HR case study insights
Authors: Muenstermann Bjoern , von Stetten Alexander , Laumer Sven , Eckhardt Andreas 
Published: August 2010

PurposeThe purpose of this paper is to enhance the understanding of business process standardization and how it contributes to generating business value. This research is a step towards a solid theoretical framework around business process standardization.Design/methodology/approachA single case study conducted in a global operating company is completed. Standardization of a certain business process (in this case the recruiting process) is shown to contribute to business value.FindingsBy standardizing its recruiting process, the company was able to reduce the “time‐to‐hire” from 92 to 69 days and the overall costs of the recruiting process by about 30 percent. The quality of the applicant data has clearly improved. Clarity and transparency of the recruiting process could be increased, while the administrative expense within the human resources (HR) departments in the distinct business locations could be reduced significantly.Research limitations/implicationsAs with every case study, the generalizability of these findings is limited because the results are based on a single case only and because the focus has been solely on one process – the recruiting process – and did not include other business processes.Practical implicationsThe case study can be useful for any company that intends to standardize its recruiting process. Clear indications of how to achieve business value out of process standardization are given.Originality/valueThe paper provides a clear definition of what business process standardization is and how it can lead to increased business value. Clear indications of how to achieve increased business value by business process standardization are provided for practitioners.