bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the impact of agricultural drainage ditch management on in-stream bacterial communities involved in nitrogen cycling: insights from the Environmental Change One Health Observatory (ECO2)
Authors: Guo Galen , Lapen David R. , Khan Izhar U. H. , Sunohara Mark , Craiovan Emilia , Chen Wen 
Published: May 2024

IntroductionAgricultural drainage ditches are essential for maintaining flow efficiency and are often managed by brushing (i.e., vegetation clearing along ditch banks) and dredging. These maintenance practices not only impact flow but also the ditches’ capacity to process and assimilate agricultural chemicals. However, the influence of ditch management on microbial activities, essential in processing and transforming these contaminants, remains underexplored.MethodsWe conducted a four-year surface water sampling campaign in two long-established (over 40 years) agricultural drainage ditches situated in eastern Ontario, Canada. One drainage ditch underwent intensive bank brushing and channel dredging, while the other remained unmanaged. We assessed the impact of these contrasting ditch management practices on the diversity and compositional structure of surface water microbiome communities, with a particular focus on the distribution of genes associated with nitrogen (N) cycling, using shotgun metagenomics sequencing and an assembly-based metagenome approach.Results and discussionFrom 117 surface water samples, we reconstructed 157 metagenome-assembled genomes (MAGs), predominantly from the Patescibacteria superphylum. Brushing alone, conducted about 10 months prior to dredging, had an insignificant impact on the aquatic microbial community. However, dredging led to a significant reduction in community diversity and abundance of genes affiliated with denitrification, dissimilatory nitrate reduction to ammonia, and complete nitrification through comammox. Ditch management resulted in noticeable shifts in the microbial community, evidenced by the enrichment of taxa in Polaromonas, Emticicia, Flectobacillus, and Patescibacteria in the water of the managed ditch sites. The metagenomes of these taxa harbor genes involved in various nitrogen biotransformation pathways. Interestingly, following dredging, the levels of ammonia and ammonium, nitrite, and total Kjeldahl N in the managed ditch did not increase, but significantly decreased; likely due to ditch substrate removal and potentially increased flow efficiency and dilution. Being one of the few studies conducted to date, this study provided unique insights into the consequences of drainage ditch management on freshwater microbiomes involved in N cycling.
Robot-assisted laparoscopic combined with endoscopic partial gastrectomy (RALE-PG) for the treatment of gastric gastrointestinal stromal tumors in challenging anatomical locations: single-center experience
Authors: Jian Chenxing , Huang Xinxiang , Lin Ruirong , Yang Weijin , Zheng Shiyao , He Hongxin , Jin Shangkun , Yang Chunkang , Guan Shen 
Published: May 2024

BackgroundGastric gastrointestinal stromal tumors in challenging anatomical locations are difficult to remove.MethodsThis study retrospectively analyzed the clinical data of 12 patients with gastric GISTs in challenging anatomical locations who underwent robot-assisted laparoscopic combined with endoscopic partial gastrectomy (RALE-PG) and manual suturing of the gastric wall.ResultsThis study included 12 patients with a mean age of 56.8 ± 9.8 years and a mean BMI of 23.9 ± 1.9 kg/m2. Tumors were located in the GEJ (n = 3), lesser curvature (n = 3), posterior gastric wall (n = 3) and antrum (n = 3). The cardia and pylorus were successfully preserved in all patients regardless of the tumor location. The mean tumor size was 4.5 ± 1.4 cm. The mitotic-count/50 mm2 was less than 5 in all patients (100%). There was no intraoperative tumor rupture (0%) and no conversion to open surgery (0%). The median operation time was 122 (97–240) min, and the median blood loss volume was 10 (5–30) ml. The median postoperative VAS score was 2 (2–4). The median time to first flatus was 2 (2–3) days. The median time to first fluid intake was 2 (2–3) days. The median time to first ambulation after the operation was 3 (2–4) days. No cases of anastomotic stenosis or leakage were found. The median time to drain removal for 6 patients was 5 (4–7) days. The median time to nasogastric tube removal for all patients was 2 (1–5) days. The median postoperative hospital stay was 5 (4–8) days. One patient (female/41 year) developed moderate anemia (Clavien-Dindo grade II complication). There was no unplanned readmission within 30 days after the operation. The median distance from the tumor to the resection margin was 1 (1–2) cm. R0 resection was achieved in all patients. The median follow-up period was 19 (10–25) months, and all patients survived with no recurrence or metastasis.ConclusionsRALE-PG is a safe, feasible and advantageous technique for treating GISTs in challenging anatomical locations. It can be used to accurately remove the tumor while preserving gastric function to the greatest extent, but long-term oncologic outcomes need to be evaluated in a study with a larger sample size and longer follow-up period.
Kidney Cancer and Potential Use of Urinary Extracellular Vesicles
Authors: Le Linh Nguy-Hoang , Munir Javaria , Kim Eun-Bit , Ryu Seongho 
Published: May 2024

Kidney cancer is the 14th most common cancer globally. The 5-year relative survival rate of kidney cancer at a localized stage is 92.9% and it declines to 17.4% in metastatic stage. Currently, the most accurate method of its diagnosis is tissue biopsy. However, the invasive and costly nature of biopsies makes it undesirable in many patients. Therefore, novel biomarkers for diagnosis and prognosis should be explored. Urinary extracellular vesicles (uEVs) are small vesicles (50–200 nm) in urine carrying nucleic acids, proteins and lipids as their cargos. These uEVs’ cargos can provide non-invasive alternative to monitor kidney health. In this review, we have summarized recent studies investigating potential use of uEVs’ cargos as biomarkers in kidney cancer for diagnosis, prognosis and therapeutic intervention.
Outcomes of Lung Transplantation in Patients With Right Ventricular Dysfunction: A Single-Center Retrospective Analysis Comparing ECMO Configurations in a Bridge-to-Transplant Setting
Authors: Lee Su Yeon , Ahn Jee Hwan , Kim Ho Cheol , Shim Tae Sun , Kang Pil-Je , Lee Geun Dong , Choi Se Hoon , Jung Sung-Ho , Park Seung-Il , Hong Sang-Bum 
Published: May 2024

This study aimed to assess the lung transplantation (LT) outcomes of patients with right ventricular dysfunction (RVD), focusing on the impact of various extracorporeal membrane oxygenation (ECMO) configurations. We included adult patients who underwent LT with ECMO as a bridge-to-transplant from 2011 to 2021 at a single center. Among patients with RVD (n = 67), veno-venous (V-V) ECMO was initially applied in 79% (53/67) and maintained until LT in 52% (35/67). Due to the worsening of RVD, the configuration was changed from V-V ECMO to veno-arterial (V-A) ECMO or a right ventricular assist device with an oxygenator (Oxy-RVAD) in 34% (18/67). They showed that lactic acid levels (2–6.1 mmol/L) and vasoactive inotropic score (6.6–22.6) increased. V-A ECMO or Oxy-RVAD was initiated and maintained until LT in 21% (14/67) of cases. There was no significant difference in the survival rates among the three configuration groups (V-V ECMO vs. configuration changed vs. V-A ECMO/Oxy-RVAD). Our findings suggest that the choice of ECMO configuration for LT candidates with RVD should be determined by the patient’s current hemodynamic status. Vital sign stability supports the use of V-V ECMO, while increasing lactic acid levels and vasopressor needs may require a switch to V-A ECMO or Oxy-RVAD.
INTELLECTUAL OPTIMIZATION OF MANAGEMENT IN ORGANIZATIONAL MEDICAL SYSTEMS BASED ON THEIR FUNCTIONING
Authors: Тишуков Б.Н. , Львович Я.Е. , Новикова Е.И. , Короткевич С.И. 
Published: May 2024

Цифровая трансформация в организационных медицинских системах, примерами которых служат поликлиники, диспансеры, медицинские центры, создает предпосылки для непосредственного цифрового управления по аналогии с технологическими системами. Технологические системы за несколько десятилетий прошли путь от микропроцессорного управления до современного способа преобразования цифровых данных в управленческие решения посредством интернета вещей. В организационных системах преобладает принятие решений в режиме административного управления. Поэтому требуется разработка методов, содействующих цифровизации в принятии управленческих решений в сфере здравоохранения. Целью работы является разработка метода интеллектуальной оптимизации, позволяющего трансформировать цифровые данные о функционировании исследуемых медицинских систем в управленческие решения в цифровом виде. Такая возможность достигается за счет интеграции в единой вычислительной среде интеллектуальной обработки и анализа цифровых ресурсов с использованием машинного обучения нейронных сетей и численной оптимизации на основе рандомизированной схемы решения задачи булевого программирования, которая адекватно отражает процесс преобразования исходной информации в выбор оптимального варианта управленческих действий по повышению эффективности и качества функционирования организационных медицинских систем
Digital transformation in organizational medical systems, examples of which are polyclinics, dispensaries, medical centers, creates prerequisites for direct digital management by analogy with technological systems. Technological systems have gone from microprocessor control to a modern way of converting digital data into management solutions through the Internet of Things over several decades. In organizational systems, decision-making in the mode of administrative management prevails. Therefore, it is necessary to develop methods that promote digitalization in making managerial decisions in the field of healthcare. The aim of the work is to develop an intelligent optimization method that allows to transform digital data on the functioning of the studied medical systems into management solutions in digital form. This possibility is achieved by integrating intelligent processing and analysis of digital resources in a single computing environment using machine learning of neural networks and numerical optimization based on a randomized scheme for solving a Boolean programming problem, which adequately reflects the process of converting initial information into choosing the optimal variant of managerial actions to improve the efficiency and quality of functioning of organizational medical systems
Medical students’ perspectives on a longitudinal wellness curriculum: a qualitative investigation
Authors: Velez Camila , Gendreau Pascale , Saad Nathalie 
Published: May 2024

Introduction: There is growing concern about the mental health status of medical students. Medical students are at a higher risk for depression, anxiety, and burnout than non-medical students. The Undergraduate Medical Education (UGME) Office of Medical Learner Affairs at McGill University developed a Longitudinal Wellness Curriculum (LWC) to foment medical students’ well-being, self-care, and adaptability.
Methods: We conducted a qualitative descriptive study to explore students’ experiences with the LWC. We conducted three semi-structured focus groups involving a total of 11 medical students. We used thematic framework analysis for data analysis.
Results: We found four main themes related to participants’ engagement with the curriculum: 1) diverse perceptions on curriculum relevance and helpfulness; 2) the benefits of experiential sessions, role model speakers, and supportive staff; 3) insights on student-friendly curriculum scheduling; and 4) the importance of wellness education and systemic interventions in medical education.
Conclusions: Most participants found the curriculum valuable and supported its integration into the academic curriculum. Experiential and active learning, diverse approaches to wellness, small group sessions, role modeling, and student-centered approaches were preferred methods. Inconvenient curriculum scheduling and skepticism over system-level support were seen as barriers to curriculum engagement and uptake. The findings of our study contribute to the development and implementation of wellness curriculum efforts in medical education.
LIRA-less: a new procedure of incisional hernia repair in Ambulatory Surgery Centers
Authors: de la Herranz Guerrero P , Lara Fernández Y , Guerrero Ramírez JL , Aguilar Márquez A , Gila Bohórquez A , García Moreno JL , Gómez Menchero J 
Published: May 2024

Resumen

La hernia incisional es uno de los procedimientos más comunes en las unidades de Cirugía General, con una incidencia en torno al 3-29% de las laparotomías. Con la introducción de la cirugía laparoscópica ha disminuido la estancia hospitalaria postoperatoria en el tratamiento de la hernia ventral, debido a una reducción de el dolor postoperatorio y de la morbilidad derivada de la herida quirúrgica. Actualmente, con la adaptación de protocolos se ha podido desarrollar la inclusión de esta patología en régimen de Cirugía Mayor Ambulatoria (CMA), en defectos de pequeño y mediano tamaño, siendo la técnica LIRA (laparoscopic intracorporeal rectus aponeuroplasty) un procedimiento seguro y eficaz en pacientes seleccionados.
Discharge and follow-up in major ambulatory surgery for abdominal wall surgery
Authors: Rosel Jódar Salcedo C , Suárez Grau JM , Moreno Suero F , Sánchez Arteaga A , Tallón Aguilar L 
Published: May 2024

Resumen

Las hernias umbilicales son las segundas hernias mas frecuentes de la pared abdominal tras las hernias inguinales, con una prevalencia del 2%. Distintas técnicas quirúrgicas se han desarrollado a lo largo de los años, desde técnicas con tensión (rafias) hasta técnicas sin tensión mediante la colocación de mallas, variando la técnica según el tipo de malla utilizada y el plano de colocación de la misma, así como el abordaje abierto o laparoscópico. Múltiples estudios afirman que el uso de plastias disminuye el riesgo de recidiva de las hernias mayores de 1-2cm, pudiendo ascender hasta el 27% en algunas series.

El objetivo de este video es mostrar paso a paso una hernioplastia abierta preperitoneal con malla plana de polipropileno no preformada, al ser la técnica más extendida actualmente para la reparación abierta de la hernia umbilical, puesto que es una técnica fácilmente reproducible y que puede realizarse en régimen de cirugía ambulatoria.
Endoscopic retromuscular eventroplasty (eTEP) in supraumbilical eventration secundary to venriculoperitoneal bypass catheter
Authors: Rubio Castellanos C , Bellido Luque JA , Alpizar Rivas O , Sánchez-Matamoros Martin I , Nogales Muñoz AL 
Published: May 2024

Resumen

La eventroplastia totalmente endoscópica retromuscular se encuentra actualmente en fase de desarrollo. Diferentes estudios publicados en la literatura objetivan diferentes ventajas clínicas si se compara con el abordaje clásico laparoscópico con colocación de malla intraabdominal. Presentamos un caso clínico de un paciente con una eventración en pared anterior abdominal en línea media supraumbilical, M3W2, secundaria a la colocación de un catéter de derivación ventrículoperitoneal al cual se le realizó una eventroplastia totalmente endoscópica retromuscular (eTEP) para su reparación.
Criterios de selección en cirugía mayor ambulatoria de pared abdominal.
Authors: Merino Díez E , Suárez Grau JM , de Jesús Gil A , Tallón Aguilar L , Mateo Retuerta J , Tkacikova E 
Published: May 2024

Resumen

La reparación de pared abdominal como cirugía mayor ambulatoria es aquella que no requiere que el paciente pernocte en el centro hospitalario. Para que se realice de manera eficiente y segura se debe seleccionar a los pacientes candidatos a este tipo de cirugía. Están descritos criterios de selección y exclusión para todos los procedimientos que se realizan como cirugía mayor ambulatoria, son muy variados y tienen en cuenta factores del paciente, de la intervención quirúrgica y anestesia entre otros. En este trabajo se quiere concretar y resumir los criterios a considerar para cirugía mayor ambulatoria específica de la reparación de pared abdominal.
Prehabilitation of the patient and the abdominal wall in ambulatory major surgery
Authors: Cabrera Bermón JM , Monje Salazar C , Buendía Peña E , González Cano J , Mansilla Díaz S 
Published: May 2024

Resumen

Introducción. La prehabilitación del paciente con hernia ventral ha demostrado estar asociada a una disminución en la incidencia de complicaciones postoperatorias y recidiva. Actualmente no existen trabajos con alto nivel de evidencia que avalen protocolos definidos. No obstante, en los últimos años existe un creciente interés en torno a este tema. Por ello, el objetivo del presente trabajo es realizar una actualización bibliográfica al respecto.

Métodos: Revisión de artículos científicos consultando la base de datos MedLine.

Resultados: Se revisaron un total de 32 artículos, destacando 3 ensayos clínicos randomizados y 12 revisiones sistemáticas.

Conclusiones: Los estudios revisados demuestran la importancia de la prehabilitación del paciente y de la pared abdominal en la optimización de los resultados postquirúrgicos. Sin embargo, son necesario estudios con un alto nivel de evidencia que especifiquen protocolos definidos.
Use of self-adhesive mesh in ambulatory surgery. Utility and advantages.
Authors: González Minchón JA , Suárez Grau JM , Pineda Navarro N , García Fernández N , Balongo García R 
Published: May 2024

Resumen

Introducción: La patología herniaria supone una de las patologías más prevalentes en el ámbito quirúrgico. El desarrollo de nuevas mallas y nuevos materiales de fijación ha supuesto un avance en el manejo quirúrgico de la hernia.

Material y métodos: La tendencia en la cirugía de la hernia va dirigida al uso de mallas de baja densidad, con gran capacidad de integración, asociándose con una disminución del dolor postoperatorio y sensación a cuerpo extraño, mejorando el tiempo de recuperación del paciente, sin aumentar el índice de recidiva a corto plazo. En cuanto al tipo de fijación usada, las mallas autofijables han demostrado beneficios respecto a las próstesis convencionales, consiguiendo una reducción del tiempo quirúrgico, disminuyendo el dolor postoperatorio y permitiendo una rápida incorporación del paciente a la rutina diaria.

Conclusiones: El uso de mallas autoadhesivas supone una alternativa eficaz en la reparación herniaria, disminuyendo el tiempo quirúrgico y anestésico, y asociando menos dolor en el postoperatorio.
الدبلوماسية الإسلامية الخارجية في العهد النبوي (1هـ/623م - 11هـ/632م)
Authors: محمود وشاح د.غسان , سلمان أبو معمر أ.سمية 
Published: May 2024

اهتمت الدولة الإسلامية بالدبلوماسية الخارجية في العهد النبوي (1-11هـ/623-632م) وتطرقت الدراسة إلى دبلوماسية النبي r في إرسال الرسل والسفراء والوفود، وكتابة الرسائل وصياغتها بطريقة غاية في الدبلوماسية وإرسالها بطريقة دبلوماسية للأطراف خارج الدولة، ثم ختمت الدراسة بخاتمة اشتملت على أهم النتائج، التي توصلت إليها الدراسة، ثم قائمة المصادر والمراجع.
Dampak Pandemi Covid-19 Terhadap Volume Ekspor Dan Impor Beras Di Indonesia
Authors: Sahputra Eka , Hasanuddin Hasanuddin , Sari Romida Rifiana , Eviatun Esti 
Published: May 2024

This research aims to see the influence of the Covid-19 pandemic on the volume of exports and imports of Indonesian rice commodities compared to the period before the Covid-19 pandemic using data for three years before the Covid-19 pandemic was officially announced in Indonesia. This research uses a library study method by using data collected and then studying and reading several library sources via electronic media. The library sources used in this paper are scientific journals and secondary sources in the form of data that has been processed by government agencies. The results of this research show that there was a decrease in the average volume of exports and imports of Indonesian rice commodities during the Covid-19 pandemic which was caused by restrictions on the mobility of goods and services entering from abroad as part of the implementation of health protocols.

Keywords : Covid-19, Ekspor, Impor
Pengaruh Dana Transfer Ke Daerah Dan Dana Desa Terhadap Tingkat Kemiskinan Desa Dengan Pendapatan Asli Daerah Sebagai Variabel Moderasi
Authors: Hasan Saukani , Iskandar Dadang Ishak , Rumianti Susti 
Published: May 2024

Poverty is a social problem that has always been an important issue in regional development programs because it is related to people's welfare. This research was conducted to determine the magnitude of the influence of Regions' Transfer Funds and Village Funds directly on the Poverty Level as well as by moderating Local Own-source Revenue in East Java during the period 2015–2021. The research population was 29 districts in East Java Province. Data with an observation span of 7 years resulted in 203 datasets in the form of historical data on Regional Original Income, Transfer Funds to Regions, Village Funds, and Regional Expenditures, and the number of poverty figures collected from the official website of the Ministry of Finance and Indonesia's central statistical agency. The data analysis method used is the SEM-PLS analysis model. The results showed that the Village Fund variable had a positive effect on the Poverty Level, but Regions' Transfer Funds had no effect while Local Own-source Revenue did not moderate the effect of Regions' Transfer Funds and Village Funds on Poverty Levels.

Keywords : Regions' Transfer Funds, Village Fund, Poverty Level, Local Own-source Revenue
SMOKE PROTECTION OF A DOUBLE-TRACK SUBWAY TUNNEL
Authors: Абашкин А.А. , Колчев Б.Б. , Хасанов И.Р. 
Published: May 2024

В статье рассмотрены особенности организации систем противодымной защиты в двухпутных тоннелях метрополитенов. Представлена расчетная методика параметров системы противодымной вентиляции с учетом фактора продольного уклона, мощности тепловыделения очага пожара, характеристик тоннеля. Предложены различные схемы приточно-вытяжных систем противодымной вентиляции в двухпутных тоннелях Московского метро.
The article discusses the features of arrangement of smoke protection systems in double-track subway tunnels. The calculation method for the smoke ventilation system parameters is presented, taking into account the factor of longitudinal slope, the heat release power of the fire source, as well as the tunnel characteristics. There are proposed the various schemes of supply and exhaust smoke ventilation systems in double-track tunnels of the Moscow Metro.
La pandèmia de la Covid-19 des de l’àlbum il·lustrat infantil: patrons narratius, pedagogia literària i canonicitat sobrevinguda
Authors: ESCANDELL DARI 
Published: May 2024

Resum
La pandèmia de resultes de la Covid-19 va significar un sotrac a escala global sense precedents. La declaració d’emergència sociosanitària, el confinament domiciliari o el contagi, l’hospitalització i l’adeu sobtat de familiars i coneguts que emmalaltiren provocà efectes colaterals devastadors de caire psicològic difícils d’entendre a ulls dels més petits. Davant d’aquesta tessitura complexa, la literatura catalana infantil va saber fer valdre la seua consuetudinària funció pedagògica creant un corpus diligent de lectures entenedores i entendridores. Aquest article analitza els nous patrons narratius esdevinguts inopinadament tendència en l’ingent sector de l’àlbum iŀlustrat: textos de no-ficció sobre virologia i microorganismes; obres introspectives que expliquen biaixos emocionals patits pels adults; llibres que aborden, des de la naturalitat més tendra i suggestiva, la circumstància de la malaltia o la pèrdua d’algú estimat; etc. Aquest escenari renovellat de títols i temàtiques fa indispensable una recerca exhaustiva d’indicis definidors de la traçabilitat d’un nou cànon summament mutable.