bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical pressure (Pc) and critical temperature (Tc) of Midra shale
Authors: Alipour Mehdi , Sakhaee-Pour A. 
Published: May 2024

AbstractThe critical pressure (Pc) and critical temperature (Tc) of shale gas depend on the characteristic pore size because of the importance of fluid–rock interactions in the matrix. This size dependency is neglected in highly permeable formations, where gas composition is only implemented because the fluid–fluid interactions are dominant. This study determines the critical properties by accounting for the characteristic pore size in the shale matrix and gas composition. The analyzed components are carbon dioxide, ethane, methane, n-butane, nitrogen, pentane, and propane. It shows that the bulk properties overestimate the actual critical properties. The overestimation varies between 15 and 26% in a uniform 5 nm conduit with a circular cross section, and it increases nonlinearly when decreasing the conduit size. Overestimation versus size is presented to provide a convenient tool for correcting the existing data. This study also determines the critical properties of Midra shale by accounting for the pore-throat size and pore-body size distributions. The former distribution is based on the mercury injection capillary pressure measurements of eight samples, whereas the latter is based on the nitrogen adsorption measurements of six samples. This study indicates that common bulk properties overestimate the critical properties of the studied shale between 5 and 22%. The results have applications in characterizing multiphase transport in shale gas reservoirs.
Programmed Cell Death-Related Gene Signature Associated with Prognosis and Immune Infiltration and the Roles of HMOX1 in the Proliferation and Apoptosis were Investigated in Uveal Melanoma
Authors: Zhao Yubao , Wang Liang , Li Xiaoyan , Jiang Junzhi , Ma Yan , Guo Shuxia , Zhou Jinming , Li Yingjun 
Published: May 2024

Abstract
Background
Uveal melanoma (UVM) is the most common primary ocular malignancy, with a wide range of symptoms and outcomes. The programmed cell death (PCD) plays an important role in tumor development, diagnosis, and prognosis. There is still no research on the relationship between PCD-related genes and UVM. A novel PCD-associated prognostic model is urgently needed to improve treatment strategies.

Objective
We aim to screen PCD-related prognostic signature and investigate its proliferation ability and apoptosis in UVM cells.

Methods
The clinical information and RNA-seq data of the UVM patients were collected from the TCGA cohort. All the patients were classified using consensus clustering by the selected PCD-related genes. After univariate Cox regression and PPI network analysis, the prognostic PCD-related genes were then submitted to the LASSO regression analysis to build a prognostic model. The level of immune infiltration of 8-PCD signature in high- and low-risk patients was analyzed using xCell. The prediction on chemotherapy and immunotherapy response in UVM patients was assessed by GDSC and TIDE algorithm. CCK-8, western blot and Annexin V-FITC/PI staining were used to explore the roles of HMOX1 in UVM cells.

Results
A total of 8-PCD signature was constructed and the risk score of the PCD signature was negatively correlated with the overall survival, indicating strong predictive ability and independent prognostic value. The risk score was positively correlated with CD8 Tcm, CD8 Tem and Th2 cells. Immune cells in high-risk group had poorer overall survival. The drug sensitivity demonstrated that cisplatin might impact the progression of UVM and better immunotherapy responsiveness in the high-risk group. Finally, Overespression HMOX1 (OE-HMOX1) decreased the cell viability and induced apoptosis in UVM cells. Recuse experiment results showed that ferrostatin-1 (fer-1) protected MP65 cells from apoptosis and necrosis caused by OE-HMOX1.

Conclusion
The PCD signature may have a significant role in the tumor microenvironment, clinicopathological characteristics, prognosis and drug sensitivity. More importantly, HMOX1 depletion greatly induced tumor cell growth and inhibited cell apoptosis and fer-1 protected UVM cells from apoptosis and necrosis induced by OE-HMOX1. This work provides a foundation for effective therapeutic strategy in tumour treatment.
Dietary Modulations in Preventing Cardiometabolic Risk in Individuals with Type 2 Diabetes
Authors: Dal Nursel , Bilici Saniye 
Published: May 2024

Abstract
Purpose of Review
Type 2 diabetes mellitus (T2DM) is a complex health issue include obesity, high cholesterol, high blood pressure, and chronic inflammation that increase the risk of cardiovascular diseases (CVDs). CVDs are of great concern in the disease progression and prognosis of T2DM. This review is a comprehensive examination of the literature on the relationship between T2DM and cardiovascular risk, nutrition-related cardiometabolic risk (CMR) factors, and impact of dietary modulations on CMR.

Recent Findings
In recent years the researches has been focus on the importance of a comprehensive treatment approach like dietary modulations to address multiple cardiovascular risk reductions, including hypertension and dyslipidemia. Modulation of dietary patterns are the most promising interventions to prevent CMR factors and T2DM via affecting the body weight, glucose control, and microbial diversity of individuals. Current evidence suggests that high-quality dietary patterns such as the Dietary Approaches to Stop Hypertension (DASH) eating plan and the Mediterranean diet is important in the metabolic control processes of T2DM with anti-inflammatory and antioxidant compounds, glucagon-like peptide agonist compounds, and intestinal microbiota changes.

Summary
Nutrition plays a critical role in preventing and improving CVD outcomes in patients with T2DM. Dietary modulations should be planned considering individual differences in responses to dietary composition and nutritional changes, personal preferences, eating behaviors and gut microbiota differences.
Assessment of Repetitive Controlled Ovarian Stimulation (COS) Cycles on Oocyte Donors: Impact on Oocyte Quality and Viable Embryo Yield
Authors: Yarkiner Zalihe , Boynukalın Fazilet Kübra , Coban Önder 
Published: May 2024

AbstractThe utilization of donor eggs has broadened the options for Assisted Reproductive Technology (ART) among women facing challenges with egg quantity or quality. Given that donors are typically selected from young and fertile individuals, In Vitro Fertilization with egg donation (IVF-ED) tends to exhibit higher rates of implantation, pregnancy, and live births compared to IVF with the woman's own eggs, especially for females over 35 years old. This has led to a projected increase in the demand for IVF-ED, surpassing the number of available donors. Consequently, many centers opt to use oocyte donors for multiple cycles. However, the correlation between repeated Controlled Ovarian Stimulation (COS) cycles and the performance of donors in terms of viable blastocyst stage embryo (VEC) or blastocyst embryo rate is not definitively established and remains of interest. This study aims to explore the preimplantation characteristics of embryo development and oocyte maturation status based on the number of donor COS cycles, employing a Generalized Linear Mixed Model (GLMM) framework. The study encompasses 1965 embryo transfer (ET) cycles involving 399 donors who underwent a minimum of two and a maximum of nine controlled ovarian hyperstimulation (COS) cycles. The findings indicate that, with the patient undergoing six or more cycles of ovarian stimulation, despite a 3.9% increase in both maturation and fertilization rates, there is a corresponding decrease of 4.5% in VEC rate and 4.7% in blastulation rates. In essence, an escalating number of donor COS cycles appears to be associated with a disadvantageous reduction in embryo quality.
Bluff retreat in North Carolina: harnessing resident and land use professional surveys alongside LiDAR remote sensing and GIS analysis for coastal management insights
Authors: Sirianni Hannah , Montz Burrell , Pettyjohn Sarah 
Published: May 2024

AbstractBluff landforms, sought-after for housing and development, present a hazard management challenge due to erosional processes despite the perceived safety of elevated land. This study focuses on the Neuse River Estuary in North Carolina, exploring coastal risk perception and erosion. A survey protocol was developed, and questionnaires targeted 246 residents with property within 100 m of the shoreline and 54 land use professionals in Craven County. To explore the connection of individual experiences with erosion, we use openly accessible LiDAR to quantify bluff retreat and erosion between 2014 and 2020, a period that encompasses Hurricane Florence in 2018. Our findings show: 1) survey results reveal a consensus among residents, with 90% observing alterations attributed to storm impacts, 2) preferences for addressing erosion lean towards structural measures, aligning with existing protection strategies (e.g., bulkheads, rip-rap) as opposed to nature-based solutions, 3) bluff tops are eroding at a higher median rate of -0.59 m per year, compared to -0.19 m per year for high sediment banks, and 4) an overall net volume decrease of approximately -1.89 cubic meters per year for Craven County, slightly more than the overall net loss for the Neuse River Estuary, which was -1.74 cubic meters per year. The findings underscore the need for a cohesive bluff erosion management plan, emphasizing the complexity of challenges and the importance of a holistic approach that combines technical studies with effective risk communication.
Knowledge and perceptions of religious leaders towards HIV prevention among young people in Lira district, Northern Uganda: a qualitative study
Authors: Murungi Tom , Kunihira Irene , Oyella Pamela , Mugerwa Moses , Gift Peruth , Aceng Mercy Jane , Puleh Sean Steven 
Published: May 2024

Abstract
Background
Currently, 410,000 new HIV infections among youth occur worldwide, which is a significant public health issue. Members of the clergy can be trustworthy allies in the reduction of HIV infections among the youth. However, little is known regarding their knowledge as well as the perceptions they hold towards HIV prevention among young people. Thus, we explored the knowledge and perceptions of religious leaders regarding HIV prevention among young people (15–24 years) in Lira district.

Methods
This was a cross-sectional qualitative study conducted among 20 religious’ leaders in March 2021 in Lira district. Religious leaders were sampled purposively and recruited from modern religions (beliefs influenced by Christianity or Islam) in Lira district. Guides for key informant interviews were utilized to gather information. Each interview was audio recorded, transcribed, and entered into NVivo version 12 software, and the data was then ready for analysis. The main themes were determined using thematic analysis.

Results
Although a few individuals had some misconceptions, the majority of participants had good knowledge about the transmission and prevention of HIV. Participants knew awareness creation, abstinence, and faithfulness in marriage as HIV prevention strategies and held positive perceptions. Perceived barriers to HIV prevention involvement were lack of knowledge and training and inadequate resources, whereas motivating factors were being respected and trusted and having easy access to young people.

Conclusion
In conclusion, religious leaders show limited HIV prevention knowledge due to religious beliefs, but understand the importance of measures like abstinence. Despite the challenges, their involvement is crucial. Addressing knowledge gaps and providing support is vital. Future efforts should emphasize both behavioral measures and interventions like condom use, post-exposure prophylaxis, and pre-exposure prophylaxis.
Social media and non-university teachers from a gender perspective in Spain
Authors: Martín-Gutiérrez Ángela , Said-Hung Elias , Conde-Jiménez Jesús 
Published: May 2024

AbstractNon-university teaching staff must use social media platforms (SMP) to update themselves on educational matters. This study aims to analyze how these teachers in Spanish non-university education, differentiating between men and women, value and use SMPs to update themselves in educational matters. A total of 463 Spanish teachers participated in this survey-type study. The results show that the perception of usefulness, responsible use, and the role of educational institutions and agents remains medium or low. At the descriptive level, differences between men and women are detected in the perceptions of the teachers surveyed, with female teachers having a more favourable perception of the usefulness, use, and role of social media assumed by the institutions in which they work professionally compared to male teachers. It is concluded that there are three profiles of non-university teachers according to the variables analyzed that do not show differences according to the sex of the teachers. The implications of this study help to propose actions that help improve the scenario by 1) increasing the training channels, 2) increasing the levels of educational innovation through SMP, 3) increasing the effectiveness of teaching–learning strategies, and 4) promoting of skills that contribute to greater use and perception of these scenarios for the training of teachers and students.
Trash, Art, and the Comics
Authors: Dyck John 
Published: May 2024

Abstract
Many comics are aesthetically trashy: They are immediately grasped and easily available. Historically, this trashiness is lobbed as an aesthetic defect of many comics, a defect for both their production and their appreciation. To defend these comics, some point to non-aesthetic values, like sociality. I argue that there is aesthetic value to these comics, and that it lies precisely in their trashy characteristics: their immediacy and availability. Many comics have these characteristics because many comics are cartooned. The immediacy of cartooning is precisely what makes so many ordinary comics beautiful in an ordinary way.
The Report Versus the Transparency Models of Appreciation: The Case of Comics
Authors: Skow Bradford 
Published: May 2024

Abstract
On the report model of appreciating fiction, one imagines learning about a fictional world through a report: reading or viewing someone’s account or listening to them tell their story. On the transparency model, one simply imagines the things that are fictional in the story, without imagining anything about how that information is acquired. It is argued that the transparency model is the default, in literature and cinema, but in comics, it is the report model that is the default.
The Role of Risk Analysis in EU Food Governance: Balancing Scientific Food Safety Factors and External Factors that Inform Risk Management for Healthier Food Systems
Authors: El Gemayel Maria 
Published: May 2024

Abstract
Scientific consensus links dietary choices to health outcomes, highlighting the urgency to prioritise healthy food production in food systems. At the EU level, however, defining healthy food and integrating it into food governance remains a challenge, particularly regarding the inclusion of health-related characteristics in food safety assessments. While the EU primarily relies on the risk analysis principle to address food safety concerns, the process still exhibits weaknesses that hinder its direct impact on fostering a healthier food production landscape. This review demonstrates how the risk analysis process, particularly scientific opinions in risk assessment and external factors (economic and political) in risk management, impact food governance and the healthiness of food systems. We find that while external factors play a crucial role in risk management decisions by incorporating non-food safety considerations, they often stem from an imbalance of power favouring major industry and political stakeholders. This imbalance disproportionately influences decision-making, often overshadowing nutritional and health aspects. To address these challenges, we recommend directing research towards filling knowledge gaps and exploring minority scientific findings, and separating external factors from risk management’s decision-making process, to ensure that food governance prioritises public health and healthy food production.
Comment on ‘Changing relationships between HIV prevalence and circumcision in Lesotho’, and ‘Age-incidence and prevalence of HIV among intact and circumcised men: an analysis of PHIA surveys in Southern Africa’
Authors: Morris Brian J. , Banerjee Joya 
Published: May 2024

AbstractTwo articles by Garenne (2023a,b) argue that voluntary medical male circumcision does not reduce human immunodeficiency virus transmission in Africa. Here we point out key evidence and analytical flaws that call into question this conclusion.
Does the linguistic market explain sociolinguistic variation in spoken Swiss Standard German?
Authors: Büchler Andrin , Bülow Lars , Britain David 
Published: May 2024

AbstractThis paper shows (a) how the concept of the linguistic market can be operationalized as an index to enable its inclusion as a factor in variationist analysis and (b) how this index helps to explain sociolinguistic variation in a diglossic situation. To do this, sociolinguistic interviews were conducted in Swiss Standard German among 16 L1-dialect-speakers aged between 19 and 40 from Biel/Bienne in western Switzerland. Drawing from participants’ self-assessments of the importance of Standard German in their professional life, a linguistic market index (LMI) was created and cross-validated with external assessments. Our variationist analysis considered four phonetic-phonological variables—/k/, /ç/, /aː/, /ɛ-ɛː/—for which typical Swiss variants (i.e., sociolinguistic stereotypes) exist. Findings show that the LMI is crucial for explaining variation in all the variables tested. Other social (i.e., gender and formality of the language production task) and linguistic factors (e.g., phonetic environment) show partial effects as well.
Jus post bellum: Scope and assessment of the applicable legal framework
Authors: Mfuranzima Noël 
Published: May 2024

Abstract
This article aims to highlight the importance of determining the temporal scope of the transition from armed conflict to peace. It will also consider the emergence of a new legal paradigm, jus post bellum, applicable to the post-conflict period, and the associated need for an appropriate regulatory framework. Given the unavoidable impact of armed conflict, the post-conflict period deserves particular attention, especially with regard to the need for a legal framework to facilitate the sustainable reconstruction of communities torn apart by conflict and ensure a lasting peace. After any kind of armed conflict, a solid legal framework is essential to finalize the end of hostilities, begin a sustainable peace process, build a united society and address the rifts caused by armed violence.
Known and potential benefits of applying herbicides with glutathione S-transferase inhibitors and inducers—a review
Authors: Carvalho-Moore Pâmela , Norsworthy Jason K. , Avent Tristen H. , Riechers Dean E. 
Published: May 2024

AbstractWeed resistance to herbicides has increased exponentially during the past 30 to 40 yr, consequently reducing the number of effective products available to control certain species and populations. Future efforts should target not only the discovery of new protein binding sites and the development of new molecules, but also the revival of old molecules with reduced efficacy due to widespread herbicide resistance. The addition of herbicide synergists that inhibit metabolic pathways or enhance intrinsic plant stress is a possible solution to ameliorate the negative effects caused by the lack of new herbicide chemistries. Glutathione S-transferase (GST) enzymes are involved with numerous herbicide detoxification reactions and plant stress responses. This review approaches the potential use of natural and synthetic GST inhibitors to enhance herbicidal activity or induce crop safety to provide effective, sustainable weed management strategies in the future.
Detection of Traveling Ionospheric Disturbances Triggered by 2022 Tonga Volcanic Eruptions Through CubeSats Coherent GNSS‐Reflectometry Measurement
Authors: Cheng Pin‐Hsuan , Wang Yang , Liu Lei , Morton Y. Jade 
Published: May 2024

AbstractWe present two case studies of traveling ionospheric disturbances (TIDs) triggered by the 2022 Tonga volcanic eruption observed by low‐cost CubeSat‐based global navigation satellite system reflectometry (GNSS‐R) measurements. The GNSS‐R data used in this work are from Spire Global CubeSats. Our analysis shows that coherent GNSS signals reflected over the ocean can be used to derive precise ionospheric total electron content (TEC) measurements. The first case shows clear TID structures with a TEC disturbance magnitude of ∼1 TEC unit (TECu) and horizontal wavelength of ∼330 km over Northwest Australia on the day of Tonga volcanic eruption. The second case shows the TIDs with ∼0.05 TECu disturbance magnitude and horizontal wavelength of ∼240 km over East Russia the day after the eruption. The second case is likely a TIDs propagated outward from Tonga for the second time after it traversed around the Earth. The GNSS‐R observed TID may be associated with the incident or reflection signal ray path. In this paper, the appropriate ray path was identified using simultaneous observations from ground receiver networks in the areas of both ray paths.
Association between time of assessment within a school year and physical fitness of primary school children
Authors: Teich Paula , Golle Kathleen , Kliegl Reinhold 
Published: May 2024

AbstractThe dissociation of effects of age, time of assessment and cohort is a well-known challenge in developmental science. We examined effects of time of assessment in the school year on children’s physical fitness using data from 75,362 German third-graders from seven cohorts. Children were tested once either in the first or second school term of third grade. Tests examined cardiorespiratory endurance (6-min run), coordination (star-run), speed (20-m sprint), lower (standing long jump) and upper (ball-push test) limbs muscle power, and flexibility (stand-and-reach test). We estimated the effect of time of assessment using a regression discontinuity design specified in a linear mixed model with random factors child and school and adjusted for age, sex, and cohort effects. Coordination, speed, and upper limbs muscle power were better in second compared to first school term, with boys exhibiting a larger increase of upper limbs muscle power than girls. There was no evidence for changes in cardiorespiratory endurance, lower limbs muscle power, and flexibility between assessments. Previously reported age and sex effects as well as secular fitness trends were replicated. There is thus evidence for improvement of some physical fitness components beyond age and cohort effects that presumably reflects the benefit of physical activity in physical education and other settings. Effects of assessment time should be taken into consideration in performance-based grading or norm-based selection of children.