bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Simple Method to Retrieve Cloud Properties from Atmospheric Transmittance and Liquid Water Column Measurements
Authors: Matamoros Salvador , González Josep-Abel , Calbó Josep 
Published: September 2010

Abstract
A deeper knowledge of the effects and interactions of clouds in the climatic system requires developing both satellite and ground-based methods to assess their optical properties. A simple method based on a parameterized inversion of a radiative transfer model is proposed to estimate the optical depth of thick liquid water clouds from the atmospheric transmittance at 415 nm, solar zenith angle, surface albedo, effective droplet radius, and aerosol load. When concurrent measurements of atmospheric transmittance and liquid water path are available, the effective radius of the droplet size distribution can also be retrieved. The method is compared with a reference algorithm from Min and Harrison, which uses similar data, except aerosol load. When applied to measurements performed at the Southern Great Plains site of the Atmospheric Radiation Measurement Program, the mean bias deviation between the proposed method and the reference method is only −0.08 in units of optical depth, whereas the standard deviation is only 0.46. For the effective droplet radius estimations, the mean bias deviation is −0.13 μm, and the standard deviation is 0.14 μm. Maximum relative deviations are lower than 5% and 8% for cloud optical depth and effective radius, respectively. The effects on these retrievals of the assumed aerosol optical depth and surface albedo are also analyzed.
Changes in Extreme Climate Indices for the Northeastern United States, 1870–2005
Authors: Brown Paula J. , Bradley Raymond S. , Keimig Frank T. 
Published: September 2010

Abstract
The northeastern United States is one of the most variable climates in the world, and how climate extremes are changing is critical to populations, industries, and the environment in this region. A long-term (1870–2005) temperature and precipitation dataset was compiled for the northeastern United States to assess how the climate has changed. Adjustments were made to daily temperatures to account for changes in mean, variance, and skewness resulting from inhomogeneities, but precipitation data were not adjusted. Trends in 17 temperature and 10 precipitation indices at 40 stations were evaluated over three time periods—1893–2005, 1893–1950, and 1951–2005—and over 1870–2005 for a subset of longer-term stations. Temperature indices indicate strong warming with increases in the frequency of warm events (e.g., warm nights and warm summer days) and decreases in the frequency of cold events (e.g., ice days, frost days, and the cold spell duration indicator). The strongest warming is exhibited in the decrease in frost days and the increase in growing season length. Although maximum temperatures indices showed strong warming trends over the period 1893–1950, subsequent trends show little change and cooling. Few significant trends were present in the precipitation indices; however, they displayed a tendency toward wetter conditions. A stepwise multiple linear regression analysis indicated that some of the variability in the 27 indices from 1951 to 2002 was explained by the North Atlantic Oscillation, Pacific decadal oscillation, and Pacific–North American pattern. However, teleconnection patterns showed little influence on the 27 indices over a 103-yr period.
Structural Evolution in Heating Profiles of the MJO in Global Reanalyses and TRMM Retrievals
Authors: Ling Jian , Zhang Chidong 
Published: September 2010

Abstract
Diabatic and latent heating profiles from four global reanalyses and three Tropical Rainfall Measuring Mission (TRMM) algorithms were compared: first generally for the tropics and then in the context of the Madden–Julian oscillation (MJO). Most of them exhibit three heating maxima corresponding to known convection centers over South America, Africa, and the Indian–western Pacific warm pool, but they still differ substantially in many ways. Most noticeably, a double-peak vertical structure with one peak in the upper and the other in the lower troposphere and relative weak heating over the Maritime Continent in comparison to heating over the Indian and western Pacific Oceans are clearly seen in some heating data but absent in others. Heating profiles associated with the MJO were diagnosed through composites and case studies. The composites were constructed as functions of MJO phases at three longitudes representing the Indian Ocean, Maritime Continent, and western Pacific, respectively. Four MJO events were chosen for the case studies, two over the Indian Ocean and two over the western Pacific. No consistent structural evolution of heating profiles through the life cycle of the MJO could be found either among different datasets in their composites at a given longitude and their case studies for a given individual MJO event or among different longitudes and MJO events within a given dataset. Nonetheless, the previously reported westward tilt in the heating field of the MJO, composed of low-level heating preceding deep heating in an active phase of the MJO and upper-level heating immediately following the active phase, is more likely to be observed over the western Pacific than other locations. The discrepancies among the datasets illustrate the infancy of estimating diabatic heating profiles from satellite observations and the need to improve the quality of the data assimilation products.
Assessing the Potential Impacts of Climate Change on Mountain Snowpack in the St. Mary River Watershed, Montana
Authors: MacDonald Ryan J. , Byrne James M. , Kienzle Stefan W. , Larson Robert P. 
Published: September 2010

Abstract
The St. Mary River watershed is an important international watershed that supplies irrigation water to large portions of southern Alberta, Canada, and northern Montana. The St. Mary River is fully allocated and users on both sides of the border are concerned regarding declining water supplies and increasing water demands under climate warming. Water supply in the St. Mary River is largely from snowpack in the mountainous portion of the watershed. This work assesses potential future changes in snowpack for the St. Mary River watershed under a range of general circulation model (GCM) derived future climate scenarios. The Generate Earth Systems Science (GENESYS) input spatial hydrometeorological model is used to simulate potential changes in spring snowpack, the onset of melt, and changes in snow extent for three 30-yr periods centered around 2025, 2055, and 2085. Results suggest an earlier spring and associated earlier onset of snowmelt and probable declines in maximum annual snow water equivalent (SWE) over the St. Mary River watershed are likely under most future climate scenarios used in this study. However, results are responsive to future climate scenarios, where a scenario with substantial global greenhouse gas (GHG) emission controls shows a much lower decline in total accumulated SWE over the St. Mary River watershed. Without substantial GHG emission reductions, the study does show that there could be significant changes in snowpack over the St. Mary River watershed in the future.
Tropospheric Water Vapor Transport as Determined from Airborne Lidar Measurements
Authors: Schäfler Andreas , Dörnbrack Andreas , Kiemle Christoph , Rahm Stephan , Wirth Martin 
Published: September 2010

Abstract
The first collocated measurements during THORPEX (The Observing System Research and Predictability Experiment) regional campaign in Europe in 2007 were performed by a novel four-wavelength differential absorption lidar and a scanning 2-μm Doppler wind lidar on board the research aircraft Falcon of the Deutsches Zentrum für Luft- und Raumfahrt (DLR). One mission that was characterized by exceptionally high data coverage (47% for the specific humidity q and 63% for the horizontal wind speed υh) was selected to calculate the advective transport of atmospheric moisture qυh along a 1600-km section in the warm sector of an extratropical cyclone. The observations are compared with special 1-hourly model data calculated by the ECMWF integrated forecast system. Along the cross section, the model underestimates the wind speed on average by −2.8% (−0.6 m s−1) and overestimates the moisture at dry layers and in the boundary layer, which results in a wet bias of 17.1% (0.2 g kg−1). Nevertheless, the ECMWF model reproduces quantitatively the horizontally averaged moisture transport in the warm sector. There, the superposition of high low-level humidity and the increasing wind velocities with height resulted in a deep tropospheric layer of enhanced water vapor transport qυh. The observed moisture transport is variable and possesses a maximum of qυh = 130 g kg−1 m s−1 in the lower troposphere. The pathways of the moisture transport from southwest via several branches of different geographical origin are identified by Lagrangian trajectories and by high values of the vertically averaged tropospheric moisture transport.
Perceived Risk of Cancer and Patient Reports of Participation in Decisions about Screening: The DECISIONS Study
Authors: Dillard Amanda J. , Couper Mick P. , Zikmund-Fisher Brian J. 
Published: September 2010

Background Health behavior theories suggest that high perceived risk for cancer will be associated with screening, but few studies have examined how perceived risk relates to the screening decision process. Objective To examine relationships between perceived risk of cancer and behaviors during decision making for 3 screening tests. Design Cross-sectional survey conducted between November 2006 and May 2007. Setting Nationwide random-digit dial telephone survey. Participants A total of 1729 English-speaking US adults aged 40 y and older who reported making a cancer screening decision (about breast, colon, or prostate tests) in the previous 2 y. Measurements Participants completed measures of perceived risk, information seeking, and shared decision-making tendencies. Results As perceived risk for cancer increased, patients were more likely to seek information about screening on their own (e.g., 35% of participants who perceived a high risk of cancer searched the Internet compared with 18% for those who perceived a low risk, P < 0.001) and in interactions with their physicians. As perceived risk increased, patients were also more likely to consult with more than 1 provider. Gender moderated the shared decision-making preference such that men with high perceived risks were more likely than women with high perceived risks to report they would have preferred more involvement in the decision (35% v. 9%, P = 0.001). Limitations Cross-sectional data limit causal inferences. Conclusions Higher perceived risk was associated with greater patient participation, as shown by more information seeking and greater desire for decisional involvement (moderated by gender). The results suggest that perceived risk of cancer could influence patient behavior when deciding about screening.
Patients’ Knowledge about 9 Common Health Conditions: The DECISIONS Survey
Authors: Fagerlin Angela , Sepucha Karen R. , Couper Mick P. , Levin Carrie A. , Singer Eleanor , Zikmund-Fisher Brian J. 
Published: September 2010

Background To make informed decisions, patients must have adequate knowledge of key decision-relevant facts. Objective To determine adults’ knowledge about information relevant to common types of medication, screening, or surgery decisions they recently made. Setting National sample of US adults identified by random-digit dialing. Design Cross-sectional survey conducted between November 2006 and May 2007. Participants A total of 2575 English-speaking adults aged 40 y or older who reported having discussed the following medical decisions with a health care provider within the previous 2 y: prescription medications for hypertension, hypercholesterolemia, or depression; screening tests for colorectal, breast, or prostate cancer; or surgeries for knee/hip replacement, cataracts, or lower back pain. Measurements Participants answered knowledge questions and rated the importance of their health care provider, family/friends, and the media as sources of information. Results Accuracy rates varied widely across questions and decision contexts. For example, patients considering cataract surgery were more likely to correctly estimate recovery time than those patients considering lower back pain or knee/hip replacement (78% v. 29% and 39%, P < 0.001). Similarly, participants were more knowledgeable of facts about colorectal cancer screening than those who were asked about breast or prostate cancer. Finally, respondents were consistently more knowledgeable on comparable questions about blood pressure medication than cholesterol medication or antidepressants. The impact of demographic characteristics and sources of information also varied substantially. For example, blacks had lower knowledge than whites about cancer screening decisions (odds ratio [OR] = 0.57; 95% confidence interval [CI] = 0.43, 0.75; P = 0.001) and medication (OR = 0.77; 95% CI = 0.60, 0.97; P = 0.03) even after we controlled for other demographic factors. The same was not true for surgical decisions. Limitations The questions did not measure all knowledge relevant to informed decision making, were subject to recall biases, and may have assessed numeracy more than knowledge. Conclusions Patient knowledge of key facts relevant to recently made medical decisions is often poor and varies systematically by decision type and patient characteristics. Improving patient knowledge about risks, benefits, and characteristics of medical procedures is essential to support informed decision making.
Deficits and Variations in Patients’ Experience with Making 9 Common Medical Decisions: The DECISIONS Survey
Authors: Zikmund-Fisher Brian J. , Couper Mick P. , Singer Eleanor , Ubel Peter A. , Ziniel Sonja , Fowler Floyd J. , Levin Carrie A. , Fagerlin Angela 
Published: September 2010

Background Although many researchers have examined patient involvement and patient-provider interactions within specific clinical environments, no nationally representative data exist to characterize patient perceptions of decision making and patient-provider communications across multiple common medical decisions. Objective To identify deficits and variations in the patient experience of making common medical decisions about initiation of prescription medications for hypertension, hypercholesterolemia, or depression; screening tests for colorectal, breast, or prostate cancer; and surgeries for knee or hip replacement, cataracts, or lower back pain, as well as to identify factors associated with patient confidence in the decisions. Setting National sample of US adults identified by random-digit dialing. Design Cross-sectional survey conducted from November 2006 to May 2007. Participants Included 2473 English-speaking adults age 40 and older who reported undertaking 1 or more of the above 9 medical actions or discussing doing so with a health care provider within the past 2 years. Measurements Patients reported who initiated discussions and made the final decisions, how much discussion of pros and cons occurred, whether they were asked about their preferences, and their confidence that the decision “was the right one.” Results The proportion of patient-driven decisions varied significantly across decisions (range: blood pressure: 16% to knee/hip replacement: 48%). Most patients (78%–85%) reported that providers made a recommendation, and such recommendations generally favored taking medical action. Fewer patients reported that providers asked them about their preferences (range: colon cancer screening: 34% to knee/hip replacement: 80%) or discussed reasons not to take action (range: breast cancer screening: 20% to lower back surgery: 80%). Decision confidence was higher among patients who reported primarily making the decision themselves (odds ratio [OR] = 14.6, P < 0.001) or having been asked for their preference (OR = 1.32, P < 0.01) and was lower among patients whose patient provider discussions included cons (OR = 0.74, P = 0.008). Limitations Recall biases may affect patients’ memories of their decision-making processes. Conclusions Decisions participants reported wide variations in the proportion of discussions that included a conversation about reasons not to take action or a conversation about patients’ preferences about what they would like to do. These factors appear directly related to patients’ confidence that the decision was “right.”
The Determination of the “Monetary Expression of Labor Time” (“MELT”) in the Case of Non-Commodity Money
Authors: Moseley Fred 
Published: September 2010

This paper suggests a way to determine the “monetary expression of labor” (the “MELT”) in today’s regime of inconvertible credit money, a way that is consistent with Marx’s general theory of money and is quantitatively the same as Marx’s determination of the MELT in the case of the inconvertible fiat money of his time. In order to explain this method of determination of the MELT in the case of modern inconvertible credit money, the paper first reviews Marx’s determination of the MELT in the case of commodity money and in the case of the inconvertible fiat money of his time. The final section of the paper discusses the similarities and the differences between my interpretation and Saros’s (2007) interpretation of the MELT in the case of inconvertible fiat money. JEL classification: B51, E11
Incidence of myelodysplastic syndromes in patients receiving concurrent myelosuppressive chemotherapy and pegfilgrastim
Authors: Covert Wendy M , Murillo Jose R , Cox James E 
Published: September 2010

Background. The World Health Organization classifies myelodysplastic syndromes (MDS) as a group of hematologic malignancies where at least one myeloid lineage contains ≥10% cells with myelodysplasia. Therapy-related MDS (t-MDS) may result from treatment with myelosuppressive chemotherapy and/or radiation. Myeloid growth factors, such as pegfilgrastim, have also been investigated as a possible risk factor for development of t-MDS. National guidelines and myeloid growth factor prescribing information recommend administering myeloid growth factors after a minimum of 24 h following myelosuppressive chemotherapy. Some evidence suggests that administering myeloid growth factors and myelosuppressive chemotherapy concurrently may increase the risk of developing t-MDS. Objective. To evaluate the incidence of t-MDS in patients who received pegfilgrastim and chemotherapy on the same day compared to patients receiving pegfilgrastim at least 1 day following completion of their chemotherapy. Methods. A retrospective chart review was performed to identify all patients who received myelosuppressive chemotherapy and pegfilgrastim on the same day between January 2003 and December 2007. Any initial diagnosis of t-MDS was clinically confirmed. Results. A total of 227 patients received myelosuppressive chemotherapy and pegfilgrastim on the same day. Median time to follow-up was 3.47 years (IQR 1.15). Two patients had a confirmed diagnosis of t-MDS. The incidence of t-MDS in patients receiving concurrent myelosuppressive chemotherapy and pegfilgrastim in our study population is 0.88%. Conclusion. Administering pegfilgrastim at least 1 day after myelosuppressive chemotherapy may help reduce the risk of t-MDS, but more studies with longer follow-up are needed to confirm this finding.
Key components of intravenous chemotherapy labeling: A systematic review and practice guideline
Authors: Trudeau Maureen , Green Esther , Cosby Roxanne , Charbonneau Flay , Easty Tony , Ko Yooj , Marchand Patti , David U , Berger Nadia , Hertz Sherrie 
Published: September 2010

Objective. To determine the necessary components and formatting of an intravenous chemotherapy label to maximize safe delivery and minimize errors. Date sources. The MEDLINE and EMBASE databases (up to April 2009) were searched for relevant evidence. Reference lists from retained studies were then searched for additional trials. An environmental scan was also conducted to locate other published and unpublished sources of information. Study selection. Relevant articles were selected and reviewed by one methodologist. Articles were selected for inclusion if they were published English language reports of Phases II or III randomized controlled trials, other comparative studies, single-arm studies, practice guidelines, or systematic reviews with or without meta-analyses, which related to the study question. MEDLINE and EMBASE searches yielded 685 potential studies of which 17 met the inclusion criteria. The environmental scan located one guideline. Three additional relevant studies were identified during the external review process. In total, 21 documents met the inclusion criteria. Data extraction. Data were extracted by one methodologist. Quality of systematic reviews was assessed using the AMSTAR tool. All other studies were evaluated based on study characteristics applicable to the particular study design. Data synthesis. The evidence collected and the consensus of expert opinion of Cancer Care Ontario’s Chemotherapy Labeling Panel form the basis of a series of recommendations for the generation of intravenous chemotherapy labels including formatting, required information, and order of information. These guidelines inform the efficient, effective, and safe administration of intravenous chemotherapy. Illustrative examples are provided.
STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus–encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma
Authors: Kis Loránd L. , Gerasimčik Natalija , Salamon Daniel , Persson Emma K. , Nagy Noémi , Klein George , Severinson Eva , Klein Eva 
Published: September 2010

AbstractIn line with the B-lymphotropic nature of Epstein-Barr virus (EBV), the virus is present in several types of B-cell lymphomas. EBV expresses a different set of latent genes in the associated tumors, such as EBV nuclear antigen 1 (EBNA-1) and latent membrane proteins (LMPs; type II latency) in classical Hodgkin lymphomas (HLs). We previously reported that exposure of in vitro EBV-converted, HL-derived cell line KMH2-EBV to CD40-ligand and interleukin-4 (IL-4) induced the expression of LMP-1. Here, we show that exposure to IL-4 or IL-13 alone induced LMP-1 in the absence of EBNA-2. Induction of LMP-1 by IL-4 and IL-13 was mediated by the signal transducer signal transducer and activator of transcription 6 (STAT6) and a newly defined high-affinity STAT6-binding site in the LMP-1 promoter. IL-4 induced LMP-1 also in Burkitt lymphoma–derived lines and in tonsillar B cells infected with the EBNA-2–deficient EBV strain P3HR-1. Furthermore, coculture of EBV-carrying Burkitt lymphoma cells with activated CD4+ T cells resulted in the induction of LMP-1 in the absence of EBNA-2. Because Hodgkin/Reed-Sternberg cells are known to secrete IL-13, to have constitutively activated STAT6, and to be closely surrounded by CD4+ T cells, these mechanisms may be involved in the expression of LMP-1 in EBV-positive chronic HLs.