bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isometric responses of isolated intrapulmonary bronchioles from cats with and without adult heartworm infection
Authors: Wooldridge Anne A. , Dillon A. Ray , Tillson D. Michael , Zhong Qiao , Barney Sharron R. 
Published: February 2012

Abstract
Objective—To determine the isometric responses of isolated intrapulmonary bronchioles from cats with and without adult heartworm infection.
Animals—13 purpose-bred adult cats.
Procedures—Cats were infected with 100 third-stage larvae or received a sham inoculation, and the left caudal lung lobe was collected 278 to 299 days after infection. Isometric responses of intrapulmonary bronchiolar rings were studied by use of a wire myograph. Three cycles of contractions induced by administration of 10μM acetylcholine were followed by administration of the contractile agonists acetylcholine, histamine, and 5-hydroxy-tryptamine. To evaluate relaxation, intrapulmonary bronchiolar rings were constricted by administration of 10μM 5-hydroxytryptamine, and concentration-response curves were generated from administration of sodium nitroprusside, isoproterenol, and substance P.
Results—Compared with tissues from control cats, contractile responses to acetylcholine and 5-hydroxytryptamine were reduced in tissues from heartworm-infected cats. Relaxation to isoproterenol was significantly reduced in tissues from heartworm-infected cats. Relaxation to substance P was increased in tissues from heartworm-infected cats, but relaxation to sodium nitroprusside was unchanged.
Conclusions and Clinical Relevance—Results suggested that despite increased bronchiolar wall thickness in heartworm-infected cats, a hyperreactive response of the bronchiolar smooth muscle is not the primary mechanism of respiratory tract clinical signs. Reduced response of the airway to isoproterenol may indicate refractoriness to bronchiolar relaxation in heartworm-infected cats.
Bilateral angular carpal deformity in a dog with craniomandibular osteopathy
Authors: Fox R. , Comerford E. J. , Newitt A. , Pettitt R. 
Published: February 2012

SummaryA four-month-old West Highland White Terrier was presented to the Small Animal Teaching Hospital at the University of Liverpool with the complaint of a bilateral angular carpal deformity. A 20° valgus deformity was present in both thoracic limbs, centred on the distal radial physes. Both distal ulnas were grossly thickened and there was concomitant thickening of the rostral mandible and calvarium. The dog exhibited signs of resentment on palpation of the mandible and signs of pain were elicited on flexion and extension of both elbow joints. No signs of pain were evident on palpation of the ulnas or calvarium. Radiographic images of both ulnas showed marked amorphous periosteal new bone formation. The distal ulnar physes were closed centrally and both elbow joints had humeroulnar subluxation. Radiographic changes to the calvarium and mandibular rami were consistent with a diagnosis of craniomandibular osteopathy. A bilateral ulna ostectomy was performed to correct the angular limb deformity and elbow subluxations. Histology of the ostectomised pieces showed changes consistent with craniomandibular osteopathy.
Changements climatiques et migrations : quels risques, quelles politiques ?
Authors: Piguet Étienne , Pécoud Antoine , de Guchteneire Paul 
Published: February 2012

Résumé Cet article propose un tour d’horizon des débats relatifs aux conséquences migratoires du changement climatique. Après un bref historique, nous examinons l’impact sur les migrations des trois principaux facteurs environnementaux liés aux changements climatiques (cyclones tropicaux, fortes pluies et inondations ; sécheresses et désertification ; élévation du niveau de la mer). Les questions fondamentales que soulève la relation entre changement climatique et migration sont ensuite abordées : la multicausalité des dynamiques migratoires, les déterminants sociaux de la vulnérabilité, la diversité des types de migration et la méthodologie. Les implications politiques sont ensuite discutées, ce qui amène à aborder le cadre juridique des migrations environnementales et la responsabilité des États. La dernière section traite des orientations futures envisageables aux plans analytique et normatif.
Walking as a Meaningful Leisure Occupation: The Implications for Occupational Therapy
Authors: Wensley Ruth , Slade Anita 
Published: February 2012

Introduction: In response to growing interest in leisure in occupational therapy and the importance of understanding how occupations maintain, enhance and promote health and wellbeing, a qualitative phenomenological study was conducted to explore the experiences of walking for leisure. Method: Six healthy student participants, identified as regular walkers, were interviewed using a semi-structured format. Data were analysed following interpretative phenomenological analysis methodology. Findings: Participants expressed how and why walking was meaningful to them; the four main themes were social connectedness, wellbeing, connection to nature and achievement from a challenge. Findings suggest that occupational therapists could use walking and leisure occupations in intervention, and that there is scope for an occupational therapy perspective in health promotion. Conclusion: Determining the subjective meaning of engaging in walking as a leisure occupation has implications for occupational science and health promotion in helping to explain why people do what they do.
Trabalhos sobre formação pedagógica para a docência universitária nas reuniões anuais da anped: período 2000-2009
Authors: Bazzo Vera Lúcia , Silva Maria da Gloria Silva e 
Published: February 2012

A pesquisa trata dos trabalhos e pôsteres apresentados nas Reuniões Anuais da Associação Nacional de Pós-graduação e Pesquisa em Educação (ANPEd) de 2000 a 2009 relacionados a processos de formação pedagógica para a docência universitária. Foram localizados, inicialmente, entre os textos publicados no sítio da ANPEd e apresentados no período em questão, 63 trabalhos que tinham como tema a docência universitária. A leitura desses trabalhos permitiu verificar que eles se concentraram nas seguintes temáticas: a avaliação da aprendizagem na educação superior; as estratégias didáticas na sala de aula universitária; a docência em cursos e licenciatura; saberes e trajetórias constituintes da docência; e políticas institucionais de formação pedagógica voltadas a docentes da educação superior. Selecionando somente os trabalhos que trataram deste último tema, chegou-se a um conjunto final de 20 trabalhos publicados. Os resultados mostram aumento significativo da quantidade de trabalhos sobre o tema no período de 2005 a 2009, em relação ao período de 2000 a 2004, evidenciando maior preocupação com a oferta qualificada de formação pedagógica mediante processos intencionais disponibilizados aos docentes universitários pelas instituições às quais estão vinculados.
The Outcome of Silicone Intubation and Tube Removal in External Dacryocystorhinostomy Patients with Distal Canalicular Obstruction
Authors: Buttanri Ibrahim B. , Serin Didem , Karslioğlu Safak , Akbaba Muslime , Fazil Korhan , Acar Banu , Sevim Mehmet Sahin 
Published: February 2012

Purpose. To evaluate the outcome of silicone intubation and tube removal in external dacryocystorhinostomy (DCR) patients with distal canalicular or common canalicular obstruction. Methods Seventy-five eyes of 69 patients with distal or common canalicular obstruction who had undergone external DCR and silicone tube insertion were included in the study. Silicone tube was left in place at least for 3 months. Presence of epiphora was questioned and patency was assessed by irrigation at each control after tube removal. Results. Mean patient age was 49.8±14.4 years (range 15-78) and mean follow-up after surgery was 13.2±4.2 months (range 6-25). After tube removal, 16 eyes (21.3%) presented with epiphora and occluded canalicular systems. Two eyes (2.7%) presented with epiphora which started just after tube removal and had a patent canalicular system. Fifty-seven eyes (76%) were free of symptoms and had patent canalicular systems and 3 of these eyes (4%) had epiphora while the tube was in place. Conclusions. Silicone intubation is indicated in patients with distal or common canalicular obstruction. The majority of patients with canalicular problems are relieved of epiphora after silicone tube removal. However, the tube itself may transiently occlude the canalicular system and cause epiphora in some patients, and in some it can aid tear flow even in the presence of a patent system.
The Prevalence of Cam-Type Femoroacetabular Morphology in Young Adults and Its Effect on Functional Hip Scores
Authors: Tsitskaris Konstantinos , Sharif Khalid , Meacock Lisa M. , Bansal Mohit , Ayis Salma , Li Patrick L.S. , Elias David A. 
Published: February 2012

Pelvic computed tomography (CT) scans of forty five young adults were reviewed and the alpha angle was calculated. The patients were selected on the basis of an age of less than 40 years and the absence of any CT evidence of previous hip pathology. An alpha angle of >55° was considered positive for cam morphology. The non-arthritic hip score and the University of California Los Angeles activity score were completed by the selected group of patients. The mean age of the individuals was 33 years (range, 20 to 40). The mean alpha angle at the superoinferior position of the anterosuperior quadrant of the femoral neck was 50.1° on the right side and 49.6° on the left. The prevalence of cam morphology was found to be 20% in the right hip and 17.7% in the left hip. There was a relatively higher prevalence of cam morphology in men. We also compared the functional scores of patients with an alpha angle >55° and those with an alpha angle ≤55°. We found no statistically significant difference between the two groups for both scores.
Antibiotic Addition to Cement - is it Beneficial?
Authors: Tabutin Jacques , D'Ollonne Thomas , Cambas Pierre M. 
Published: February 2012

Antibiotic loaded acrylic cement (ALAC) is widely employed in primary as well as revision hip arthroplasties. There are prerequisites in relation to antibiotic choice and mixing techniques. The 2007 French Consensus Conference delivered recommendations for ALAC in primary arthroplasty. Decisions need to be more patient-specific in revision surgery. Appropriate use of ALAC (and associated antibiotics) and awareness of alternative possibilities such as collagen or bone graft impregnated with antibiotics may guide future practice.
Hemofiltration Circuit use beyond 72 Hours in Pediatric Continuous Renal Replacement Therapy
Authors: Ali Farah N. , Lane Jerome C. 
Published: February 2012

Introduction During continuous renal replacement therapy (CRRT), hemofiltration circuits ideally are changed after 72 h since tubing integrity and flow rates are not guaranteed after this time interval. This potential risk must be weighed against the risk of hypotension during elective circuit changes in the unstable patient. The aim of this study was to examine the safety of circuits used beyond 72 h in pediatric CRRT. Methods A retrospective chart review of all patients who underwent CRRT at our institution from January 2003 to October 2005 was performed. Procedures were divided into standard (≤72 h) and extended (>72 h) circuit duration groups. Patients who had more than one CRRT procedure (n=13) were excluded from study. Results 71 CRRT procedures were performed for 71 patients. A total of 254 circuits were used, of which 64 (25%) were used for >72 h. For circuits >72 h, the mean duration of use was 5.5 days ± 1.8 (range 4–11). There were no differences between the groups in age (p=0.12), weight (p=0.48), diagnosis (p=0.21), CRRT indication (p=0.07), CRRT mode (p=0.37), anticoagulation (p=0.53), blood flow rate (p=0.06), replacement rate (p=0.50) or dialysate rate (p=0.89). There were no incidents of membrane or tubing rupture in either group. Conclusions Use of hemofiltration circuits beyond 72 h may be safe in pediatric patients undergoing CRRT without increased risk of tubing rupture. Our data suggest a need to redefine the limits of prolonged circuit use in pediatric CRRT.
Sexual dimorphism in skeletal browridge and chin morphologies determined using a new quantitative method
Authors: Garvin Heather M. , Ruff Christopher B. 
Published: February 2012

AbstractQualitative methods of describing sexual dimorphism in discrete cranial traits have been criticized for their subjectivity and statistical limitations. However, researchers have yet to be able to accurately capture the morphology of these individual traits using traditional metric techniques. This article presents a method to quantify morphological variation in the skeletal browridge and chin using 3D surface laser scans. Browridge and chin regions are isolated from the skull using objectively defined landmarks and planes. Region areas and volumes are used to quantify absolute and relative size, while semilandmarks along transects are used for more detailed morphometric analyses. An intraobserver error study indicates high repeatability of the method. Application of the method is demonstrated on a sample of US males and females of black and white ancestries. Results suggest significant effects of both sex and ancestry on brow and chin morphologies and are consistent with traditional qualitative descriptions. Our results indicate that the method can accurately and reliably quantify browridge and chin morphologies, providing a tool to objectively describe and statistically analyze these traditionally qualitative discrete cranial traits. Am J Phys Anthropol, 2012. © 2012 Wiley Periodicals, Inc.
Autophagy Prior to Chondrocyte Cell Death During the Degeneration of Meckel's Cartilage
Authors: Yang Rong‐Tao , Zhang Chi , Liu Yong , Zhou Hai‐Hua , Li Zu‐Bing 
Published: February 2012

AbstractThe central portion of Meckel's cartilage degenerates almost immediately after birth. Whether autophagy is involved in this process remains unclear. Thus, to explore the role of autophagy during this process, we have detected the expression of autophagy and apoptosis‐related markers in embryonic mice. In E15, Beclin1 and LC3 expressions were weak and negative in Meckel's cartilage, respectively. In E16, chondrocytes of the central portion became hypertrophic. Moderate immunoreactivities of Beclin1 and LC3 were observed in prehypertrophic and hypertrophic chondrocytes of the central portion. In E17, the degradation occurred in the central portion and expanded anteriorly and posteriorly. Beclin1 expression was observed in Meckel's cartilage with an increase in the hypertrophic chondrocytes of the central portion. The expression of LC3 was detected specifically in terminally differentiated hypertrophic chondrocytes. The mRNA expressions of LC3 and Beclin1 from E15 to E17 significantly increased. This result is in accord with the histologic findings. Terminal deoxynucleotidyltransferase‐mediated dUTP‐biotin nick‐end labeling assay and Caspase 3 expression demonstrated that apoptosis was detected in the lateral part of terminal hypertrophic chondrocytes along the degeneration area of Meckel's cartilage. In addition, Bcl2 expression increased significantly from E15 to E17. These results indicate that autophagy is involved in hypertrophic chondrocytes during the degradation of Meckel's cartilage and occurs prior to chondrocyte cell death during this process. Anat Rec, 2012. © 2012 Wiley Periodicals, Inc.
Design of a Mixed Ionic/Electronic Conducting Oxygen Transport Membrane Pilot Module
Authors: Pfaff E. M. , Kaletsch A. , Broeckmann C. 
Published: February 2012

AbstractIn the last years, a lot of ceramic materials were developed that, at higher temperatures, have a high electrical conductivity and a high conductivity of oxygen ions. Such mixed ionic/electronic conductors can be used to produce high‐purity oxygen. This work focuses on the realization of a pilot membrane module, with BSCF (Ba0.5Sr0.5Co0.8Fe0.2O3‐δ) perovskite selected as the membrane material. An amount of 500 kg of powder was industrially fabricated, spray‐granulized and pressed into tubes. The best operation conditions concerning energy consumption were calculated, and a module reactor was designed operating at 850 °C, with an air pressure of 15–20 bar on the feed site and a low vacuum of about 0.8 bar on the permeate site. Special emphasis was placed on joining alternatives for ceramic tubes in metallic bottoms. A first laboratory module was tested with a membrane area of 1 m2 and then advanced to a pilot module with 570 tubes and a capability of more than 300 000 L of pure oxygen per day.
Hydrogen Permeation Properties and Chemical Stability of Novel Pd‐Free Alloy Membranes Based on the V‐Y System
Authors: Magnone E. , Jeon S. I. , Park J. H. , Fleury E. 
Published: February 2012

AbstractNo investigation has yet been accomplished to screen the yttrium‐doped effects on vanadium‐based metal membranes. Synthesis, hydrogen permeation properties, and chemical stability of a novel palladium (Pd)‐coated V99Y1 alloy membrane are presented. Hydrogen permeation experiments have been performed to investigate the hydrogen transport properties through the Pd‐coated V99Y1 alloy membrane in the pressure range of 1.5–3.0 bar under pure hydrogen as well as H2‐CO2 and H2‐CO gas mixtures at 400 °C. The maximum hydrogen permeation rate was ∼32 mL min–1cm–2 for a 0.5 mm thick membrane under pure hydrogen. The results offer new directions in the synthesis of novel non‐Pd‐based metal membranes for hydrogen separation in precombustion capture applications.
Screening of Aqueous Amine‐Based Solvents for Postcombustion CO2 Capture by Chemical Absorption
Authors: Dubois L. , Thomas D. 
Published: February 2012

AbstractIn relation with CO2 capture by chemical absorption into aqueous amine‐based solvents, absorption and regeneration parameters by separate absorption and regeneration tests are determined. An absorption parameter for different types of amine‐based solvents is evaluated by performing absorption tests at 298 K and atmospheric pressure with a gas‐liquid contactor and deducing apparent kinetic constants. The regeneration parameter is obtained from a CO2 concentration temporal profile measured in a regeneration cell at the boiling temperature of each solvent. By combining both parameters it is possible to compare the absorption‐regeneration performances of all the solvents studied. Good absorption‐regeneration performances of cyclical amines, especially of piperidine (PIP) and piperazine (PZ), are highlighted. The interesting potential of 2‐amino‐2‐methyl‐1‐propanol (AMP) and methyldiethanolamine (MDEA) activated with PZ and PIP is also considered.
A high‐performance switch architecture based on mesh of trees
Authors: Chang Hyung Jae , Qu Guannan , Zheng S.Q. 
Published: February 2012

SUMMARYWith emergence of various new Internet‐enabled devices, such as tablet PCs or smart phones along with their own applications, the traffic growth rate is getting faster and faster these days and demands more communication bandwidth at even faster rate than before. To accommodate this ever‐increasing network traffic, even faster Internet routers are required. To respond for these needs, we propose a new mesh of trees based switch architecture, called MOTS(N) switch. In addition, we also propose two more variations of MOTS(N) to further improve it. MOTS(N) is inspired by crossbar with crosspoint buffers. It forms a binary tree for each output line, where each gridpoint buffer is a leaf node and each internal node is 2‐in 1‐out merge buffer emulating FIFO queues. Because of this FIFO characteristic of internal buffers, MOTS(N) ensures QoS like FIFO output‐queued switch. The root node of the tree for each output line is the only component connected to the output port where each cell is transmitted to output port without any contention. To limit the number of buffers in MOTS(N) switch, we present one of its improved (practical) variations, IMOTS(N) switch, as well. For IMOTS(N) switch architecture, sizes of the buffers in the fabric are limited by a certain amount. As a downside of IMOTS(N), however, every cell should go through log 2N + 1 number of buffers in the fabric to be transmitted to the designated output line. Therefore, for even further improvement, IMOTS(N) with cut‐through, denoted as IMOTS‐CT(N), is also proposed in this paper. In IMOTS‐CT(N) switch, the cells can cut through one or more empty buffers to be transferred from inputs to outputs with simple 1 or 2 bit signal exchanges between buffers. We analyze the throughput of MOTS(N), IMOTS(N), and IMOTS‐CT(N) switches and show that they can achieve 100% throughput under Bernoulli independent and identically distributed uniform traffic. Our quantitative simulation results validate the theoretical analysis. Copyright © 2012 John Wiley & Sons, Ltd.
[4+2] Cycloadditions of 3‐Tetrazolyl‐1,2‐diaza‐1,3‐butadienes: Synthesis of 3‐Tetrazolyl‐1,4,5,6‐tetrahydropyridazines
Authors: Lopes Susana M. M. , Brigas Amadeu F. , Palacios Francisco , Lemos Américo , Pinho e Melo Teresa M. V. D. 
Published: February 2012

AbstractThe synthesis of new 3‐tetrazolyl‐1,4,5,6‐tetrahydropyridazines by Diels–Alder reactions of ethyl 3‐(tetrazol‐5‐yl)‐1,2‐diaza‐1,3‐butadiene‐1‐carboxylates is reported. These 1,2‐diaza‐1,3‐dienes reacted with electron‐rich heterocycles, nucleophilic olefins and cumulenes, as well as with electron‐deficient dienophiles, to give the target compounds regioselectively. Computational studies corroborated the rationalization of the observed reactivity and selectivity.
Activity scheduling as a core component of effective care management for late‐life depression
Authors: Riebe Genevieve , Fan Ming‐Yu , Unützer Jürgen , Vannoy Steven 
Published: February 2012

BackgroundActivity scheduling is an established component of evidenced‐based treatment for late‐life depression in primary care. We examined participant records from the Improving Mood‐Promoting Access to Collaborative Treatment (IMPACT) trial to identify activity scheduling strategies used in the context of successful depression care management (CM), associations of activity scheduling with self‐reported activity engagement, and depression outcomes.MethodsThis study used observational mixed methods analysis of 4335 CM session notes from 597 participants in the intervention arm of the IMPACT trial. Grounded theory was used to identify 17 distinct activity categories from CM notes. Logistic regression was used to evaluate associations between activity scheduling, activity engagement, and depression outcomes at 12 months. All relevant institutional review boards approved the research protocol.ResultsSeventeen distinct activity categories were generated. Most patients worked on at least one social and one solitary activity during their course of treatment. Common activity categories included physical activity (32%), medication management (22%), active–non‐physical (19%), and passive (14%) activities. We found significant, positive associations between activity scheduling, self‐reported engagement in activities at 12 months, and depression outcomes at 12 months.ConclusionOlder primary care patients in CM for depression worked on a wide range of activities. Consistent with depression theory that has placed emphasis on social activities, the data indicate a benefit for intentional social engagement versus passive social and solitary activities. Care managers should encourage patients to balance instrumental activities (e.g., attending to medical problems) with social activities targeting direct interpersonal engagement. Copyright © 2012 John Wiley & Sons, Ltd.