bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complications of XEN gel stent implantation for the treatment of glaucoma: a systematic review
Authors: Gan Lu , Wang Lixiang , Chen Jun , Tang Li 
Published: May 2024

AimThis study was aimed to summarize the complications and their management associated with XEN gel stent implantation.MethodsA systematic review of literature was conducted using Medline (via PubMed), EMBASE, the Cochrane Library databases, and China National Knowledge Infrastructure, from their inception to February 1, 2024.ResultsA total of 48 studies published between 2017 and 2024 were identified and included in the systematic review, including 16 original studies (retrospective or prospective clinical studies), 28 case reports, and 4 case series, which followed patients for up to 5 years. Early postoperative complications of XEN gel stent implantation include hypotony maculopathy (1.9–4.6%), occlusion (3.9–8.8%), suprachoroidal hemorrhage (SCH), choroidal detachment (0–15%), conjunctival erosion, and exposure of the XEN gel stent (1.1–2.3%), wound and bleb leaks (2.1%) and malignant glaucoma (MG) (2.2%). Mid-postoperative complications of XEN gel stent implantation included migration of XEN (1.5%), ptosis (1.2%), endophthalmitis (0.4–3%), macular edema (1.5–4.3%), hypertrophic bleb (8.8%) and subconjunctival XEN gel stent fragmentation (reported in 2 cases). Late postoperative complications reported in cases included spontaneous dislocation and intraocular degradation.ConclusionXEN gel stent implantation is a minimally invasive glaucoma surgery (MIGS) procedure for glaucoma, known for its potential to minimize tissue damage and reduce surgical duration. However, it is crucial to note that despite these advantages, there remains a risk of severe complications, including endophthalmitis, SCH, and MG. Therefore, postoperative follow-up and early recognition of severe complications are essential for surgical management.
Impact of fluid balance and opioid-sparing anesthesia within enchanced recovery pathway on postoperative morbidity after transthoracic esophagectomy for cancer
Authors: Djukanovic Marija , Skrobic Ognjan , Stojakov Dejan , Knezevic Nebojsa Nick , Milicic Biljana , Sabljak Predrag , Simic Aleksandar , Milenkovic Marija , Sreckovic Svetlana , Markovic Dejan , Palibrk Ivan 
Published: May 2024

BackgroundEnhanced Recovery After Surgery (ERAS) protocol for esophagectomy may reduce the high incidence of postoperative morbidity and mortality. The aim of this study was to assess the impact of properly conducted ERAS protocol with specific emphasis on fluid balance and opioid-sparing anesthesia (OSA) on postoperative major morbidity and mortality after esophagectomy.MethodsPatients undergoing elective esophagectomy for esophageal cancer at the Hospital for Digestive Surgery, University Clinical Center of Serbia, from December 2017 to March 2021, were included in this retrospective observational study. Patients were divided into two groups: the ERAS group (OSA, intraoperative goal-directed therapy, and postoperative “near-zero” fluid balance) and the control group (opioid-based anesthesia, maintenance mean blood pressure ≥ 65 mmHg, and liberal postoperative fluid management). The primary outcome was major morbidity within 30 days from surgery and 30-day and 90-day mortality. Multivariable analysis was used to examine the effect of the ERAS protocol.ResultsA total of 121 patients were divided into the ERAS group (69 patients) and the control group (52 patients). Patients in the ERAS group was received less fentanyl, median 300 (interquartile range (IQR), 200–1,550) mcg than in control group, median 1,100 (IQR, 650–1750) mcg, p &lt; 0.001. Median intraoperative total infusion was lower in the ERAS group, 2000 (IQR, 1000–3,750) mL compared to control group, 3,500 (IQR, 2000–5,500) mL, p &lt; 0.001. However, intraoperative norepinephrine infusion was more administered in the ERAS group (52.2% vs. 7.7%, p &lt; 0.001). On postoperative day 1, median cumulative fluid balance was 2,215 (IQR, −150-5880) mL in the ERAS group vs. 4692.5 (IQR, 1770–10,060) mL in the control group, p = 0.002. After the implementation of the ERAS protocol, major morbidity was less frequent in the ERAS group than in the control group (18.8% vs. 75%, p &lt; 0.001). There was no statistical significant difference in 30-day and 90-day mortality (p = 0.07 and p = 0.119, respectively). The probability of postoperative major morbidity and interstitial pulmonary edema were higher in control group (OR 5.637; CI95%:1.178–10.98; p = 0.030 and OR 5.955; CI95% 1.702–9.084; p &lt; 0.001, respectively).ConclusionA major morbidity and interstitial pulmonary edema after esophagectomy were decreased after the implementation of the ERAS protocol, without impact on overall mortality.
Wearing a KN95/FFP2 facemask has no measureable effect on functional activity in a challenging working memory n-back task
Authors: Montandon Marie-Louise , Haller Sven , Rodriguez Cristelle , Herrmann François R. , Giannakopoulos Panteleimon 
Published: May 2024

IntroductionWide use of facemasks is one of the many consequences of the COVID-19 pandemic.MethodsWe used an established working memory n-back task in functional magnetic resonance imaging (fMRI) to explore whether wearing a KN95/FFP2 facemask affects overall performance and brain activation patterns. We provide here a prospective crossover design 3 T fMRI study with/without wearing a tight FFP2/KN95 facemask, including 24 community-dwelling male healthy control participants (mean age ± SD = 37.6 ± 12.7 years) performing a 2-back task. Data analysis was performed using the FSL toolbox, performing both task-related and functional connectivity independent component analyses.ResultsWearing an FFP2/KN95 facemask did not impact behavioral measures of the 2-back task (response time and number of errors). The 2-back task resulted in typical activations in working-memory related areas in both MASK and NOMASK conditions. There were no statistically significant differences in MASK versus NOMASK while performing the 2-back task in both task-related and functional connectivity fMRI analyses.ConclusionThe effect of wearing a tight FFP2/KN95 facemasks did not significantly affect working memory performance and brain activation patterns of functional connectivity.
Comparison of Dutch healthy eating and healthy eating indexes and anthropometry in patients with major depression with health subjects: a case-control study
Authors: Tohidi Nafe Melika , Movahedi Ariyo , Djazayery Abolghasem 
Published: May 2024

BackgroundDiseases and disorders related to mental health are spreading like other chronic diseases all around the world. Considering the role of food in the prevention and treatment of these disorders, including major depression, investigating the relationship between different food patterns and this disorder is of particular importance. The aim of this study was to compare Dutch healthy eating and healthy eating indexes and anthropometry in patients with major depression with healthy individuals.MethodsIn this case-control study, the final analysis was performed on 67 men and 111 women with an age range of 20–30 years. Height (cm), weight (kg), food frequency questionnaire (FFQ), physical activity (MET-min/week), demographic and PHQ-9 questionnaires were taken from all participants. In the following, all the food ingredients and their components were extracted and used to calculate HEI-2015 and DHD. Statistical analysis was performed using SPSS software with independent t-test, logistic regression and chi-square.ResultsIt was found that people with major depression in this study were mostly women and occupied. The average HEI-2015 in healthy people and those with major depression was 58 and 54.3, respectively. Also, the average DHD in these people was 60.5 and 55, respectively. HEI-2015 and DHD had a significant negative correlation with depression score (r = −0.16, p-value = 0.03) (r = −0.19, p-value = 0.01). Also, in the logistic regression model, before and even after adjusting confounders, HEI-2015 and DHD had a reduced odds ratio in people suffering from major depression. The two groups did not differ significantly in terms of the average factors of height, weight and body mass index (BMI).ConclusionIt seems that HEI2015 and DHD have a significant relationship in reducing major depression. However, due to the small number of studies in this regard, especially in the field of DHD, the need for more studies seems necessary.
Urban safety and psychological distress during the pandemic: the results of a longitudinal study
Authors: Ferretti Fabio , Gualtieri Giacomo , Masti Alessandra , Uvelli Allison 
Published: May 2024

IntroductionIn the last decades, a large body of literature has explored the topic of perceived safety and fear of crime in urban environments. The effects of psychological factors on such feelings have been studied, but rarely using prospective studies, and never when these factors intercept a worldwide dramatic event like the pandemic. This research aimed to analyze the variations of the feelings of urban safety during the pandemic, the role of resiliency and the effect of psychological stressors such as anxiety, stress, and depression.MethodsDuring 2019 and 2022, before and after the pandemic, a face-to-face interview was administered to the same group of 195 participants. The PUSAS scale was used to measure unsafety, the ER89-R to assess for resiliency, the DASS-21 to collect data about the general distress (anxiety, stress and depression), and the CAS scale was used to evaluate the specific coronavirus anxiety. Structural equation models were applied to test a theoretical framework grounded on the relationships between these measures.ResultsThe research findings showed decreased feelings of unsafety across the pandemic, consistent with the literature. The positive effect of ego-resiliency was significant but only for its interaction with data collected before the pandemic, whilst stress and anxiety impacted unsafety in 2022 through different pathways. None of the symptoms of general distress influenced the concern about crime and sense of vulnerability, as the feelings of unsafety were found independent from the variations of the specific coronavirus anxiety.DiscussionAlthough the research findings did not confirm the impact of coronavirus, they presented some facets that disconfirm what the literature reported about the relationships between psychological distress and fear of crime. Implications about measurement issues are discussed.
Interdisciplinary collaborative eye examinations to protect preterm infant neurodevelopment: a quality improvement project
Authors: McCarty Dana B. , Clary-Williams Erika , LeBLond Kristen D. , Liu Tianyi , Zbornik-Thompson Tika , Ulrich J. Niklas , Go Michelle S. 
Published: May 2024

IntroductionInfants born &lt;31 weeks gestational age with birth weight ≤ 1,500 grams receive routine eye examinations to screen for Retinopathy of Prematurity (ROP) while in the Neonatal Intensive Care Unit (NICU) to help prevent vision threatening complications; however, preterm infants’ sensory systems are underdeveloped, and repeated exposure to painful stimuli is associated with worse developmental outcomes.MethodsAn interdisciplinary NICU team designed a collaborative eye exam model (CEEM) incorporating best practice recommendations for infant pain control during exams. Pain scores and vital signs were recorded before, during, and after exams. Two sets of mixed-effects regression models with a random intercept on infants were established to investigate relationships between the intervention, birth gestational age (BGA), postmenstrual age (PMA), and outcomes associated with painful stimuli. Survey feedback was elicited from NICU stakeholders about the CEEM.ResultsThirty standard of care (SC) and 35 CEEM exams of 37 infants were included in final analysis. In infants of the same BGA, the number of desaturation events was significantly reduced in the CEEM group (p = 0.003) and became 1.53 times smaller with each additional week of BGA (p = 0.009). Probability of heart rate recovery within 15 min lowered significantly in the CEEM group (p = 0.04). In SC or CEEM or between infants of the same PMA, no differences were observed for bradycardia, heart rate range, chance of heart rate recovery, or pain scores. Increases in tachycardia (p &lt; 0.001) events and desaturations p = 0.006 were discovered in the CEEM group. When considering interaction effects, the CEEM appeared to reduce the number of desaturations to a greater degree for infants at earliest BGAs with attenuation of this effect with greater BGA. Regarding PMA, bradycardia and tachycardia events were reduced for infants across PMAs in the CEEM, but the effect for tachycardia improves with age, while the effect for bradycardia diminishes with age. Stakeholders agreed that the infant’s eye exam experience and the staff experience was “very much” improved by the CEEM.DiscussionDespite variable findings in selected outcome measures, the CEEM was positively viewed by staff. Infants may benefit from the CEEM differently based on BGA and PMA.
Perception of having children through surrogacy in individuals with MRKH in Vietnam: a qualitative study
Authors: Le Thanh T. Q. , Le Nhung T. H. , Vu Tuan A. , Nguyen Hoa H. , Vuong Lan N. 
Published: May 2024

IntroductionMayer-Rokitansky-Küster-Hauser syndrome (MRKH) is rare condition that has a negative impact on quality of life because affected women lack a uterus and vagina, and are therefore unable to engage in sexual intercourse and experience natural pregnancy. This study evaluated perceptions of surrogacy in Vietnamese women with MRKH who have started families.MethodWomen with MRKH who had undergone successful vaginal reconstruction, were married, and had started families participated in a semi-structured, in-depth, one-on-one online video interview with an experienced female psychologist. Open-ended questions were used to encourage participants to express their perceptions of surrogacy; prominent themes were discussed, compared, and combined.ResultsTwenty women (mean age 31 years) agreed to participate. Key themes identified from interviews were the importance of having genetic offspring, consideration of surrogacy as a preferred solution to infertility, the barriers to surrogacy in Vietnam, lack of reproductive information and counselling, individuals concealing their health condition, the impact of religion on the possibility of surrogacy, the economic cost of surrogacy, and the difficulty in finding a surrogate under the restrictions imposed by Vietnamese law.DiscussionBased on the perceptions of women from MRKH from Vietnam, there is an opportunity to improve how infertility is managed in these people, including information about surrogacy. These data show that individuals with MRKH should be provided with information about the possibility of surrogacy, encouraged to be open and seek support, and be managed by a multidisciplinary team that includes psychological support; the provision of economic support for fertility treatments in women with MRKH should also be considered.
Musculoskeletal disorders and quality of life for Chilean teachers during the COVID-19 pandemic at the academic year-end
Authors: Vega-Fernández Gustavo , Gonzalez-Torres Carlos , Solis-Soto María , Lizana Pablo A. 
Published: May 2024

IntroductionSchoolteachers have reported multiple demands contributing to poor perceptions regarding their quality of life and high rates of musculoskeletal disorders. However, there are few studies about the association between musculoskeletal disorders and quality of life from the end of the academic period during the COVID-19 pandemic.ObjectiveEvaluate musculoskeletal disorders rates and their association with quality of life perceptions among teachers from the last academic period during the COVID-19 pandemic.Participants and methodsA total sample of 161 Chilean schoolteachers was included in a cross-sectional study musculoskeletal disorders prevalence was evaluated using the Standardized Nordic Questionnaire, and quality of life was evaluated through the Short-Form 12 Health Survey Instrument. A logistic regression was applied to evaluate the association between musculoskeletal disorders and quality of life perceptions adjusted by gender, age, and contract type.Results98% of teachers have suffered from some type of musculoskeletal disorders during the last 12 months, and 64% have had six or more painful regions. Women showed a higher musculoskeletal disorders rate than men. The group of teachers with the most musculoskeletal disorders (≥p50) saw significantly greater risk of low scores on the physical (OR: 2.16; p &lt; 0.05) and mental components (OR: 4.86; p &lt; 0.01) of quality of life, regardless of gender, age, and contract type.ConclusionHigh musculoskeletal disorders rates suggest that preventive and informative actions must be taken regarding these disorders in order to protect teachers’ mental and physical health, considering the effects of the school year and the COVID-19 health crisis.
Incidence and spontaneous clearance of gonorrhea and chlamydia infections among men who have sex with men: a prospective cohort study in Zhuhai, China
Authors: Lyu Hang , Tang Haotong , Feng Yunlong , Hu Shuyan , Wang Yuyu , Zhou Lanlan , Huang Shanzi , Li Jiarun , Zhu Huamei , He Xi , Tang Weiming , Zhou Yi , Zhang Lei 
Published: May 2024

BackgroundMen who have sex with men (MSM) face significant risks of Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) infection. Nevertheless, only limited studies have looked into the site-specific infection and clearance of CT/NG. In order to prevent transmission, it is essential to understand the underlying factors that drive infection and spontaneous clearance.MethodsA 12-week cohort study examined the association between CT/NG infection, self-clearance, and sexual behaviors among MSM. The Willingness Service recruited participants who completed weekly questionnaires and provided urine, throat, and rectal swab samples.ResultsThe study involved 151 men, in which 51 (33.8%) were diagnosed with CT/NG infection during the study period. HIV (OR = 11.31), kissing (OR = 1.59), receptive oral sex (OR = 36.64), and insertive anal sex (OR = 19.73) constituted significant risk factors. 100% condom use (OR = 5.78) and antibiotic (OR = 7.53) were more likely to cause spontaneous clearance.DiscussionMSM may engage in riskier sexual behaviors due to insufficient knowledge and awareness of STI prevention, leading to increased susceptibility to NG/CT. It is crucial to concentrate on enhancing health education for MSM.ConclusionThis study found that the rectum was the most prevalent site of CT/NG and sexual behavior can influence the infection. Additionally, the appropriate use of antibiotics and consistent condom use may contribute to clear spontaneously.
Sequência didática para o ensino remoto de astronomia para alunos do ensino médio por meio de um minicurso
Authors: França Coelho Maria Thais , Santos Noelia Souza , Da Silva Dantas Claudio Rejane 
Published: May 2024

Neste trabalho propomos uma Sequência Didática para a abordagem de tópicos de Astronomia para alunos da primeira série do Ensino Médio, por meio de um minicurso realizado no formato remoto. O referencial teórico é pautado na teoria da Aprendizagem Significativa de David Ausubel, que valoriza os conhecimentos preexistentes dos estudantes, e no conceito de UEPS. O minicurso teve uma carga horária de 8 horas-aulas sendo 6 horas-aulas de atividades síncronas e 2 (duas) horas-aulas de atividades assíncronas. Tivemos um total de 8 (oito) participantes os quais eram residentes de 3 (três) municípios da região do Cariri, localizados no Sul do estado do Ceará (Antonina do Norte, Tarrafas e Araripe). A pesquisa insere-se no contexto da abordagem qualitativa e a coleta de dados aconteceu mediante observação e registro dos fatos em diário de bordo, questionários e mapas mentais. Os resultados evidenciaram que as atividades realizadas promoveram a interação de forma plena, mesmo sendo realizadas no formato remoto. Isto nos leva a concluir que a Sequência é um instrumento bastante útil para os profissionais que desejam ensinar Astronomia no formato de minicurso remoto.
Uma revisão sobre Assistência Técnica e Extensão Rural
Authors: Nogaroli Jéssica Alves , Kupicki Felipe 
Published: May 2024

O trabalho em questão tem como objetivo apresentar um panorama histórico da Assistência Técnica e Extensão Rural, qual possui uma temática importante no desenvolvimento econômico e regional da agricultura, sendo responsável pela implementação e fortalecimento das políticas públicas para melhorias na renda e maior qualidade de vida das famílias rurais, por meio do aprimoramento dos sistemas de produção, acesso a recursos, serviços e renda. Desde seu surgimento na Inglaterra em meados do século XIX, os serviços de assistência técnica e extensão rural vêm passando por um processo de profundas mudança. O tradicional modelo deste serviço caiu em desuso e com isso uma nova política de Assistência Técnica e Extensão Rural passou a vigorar com mudanças no seu formato institucional, oferecendo serviços e estratégias de desenvolvimento rural. No Brasil, a renovação dos serviços de assistência técnica e extensão rural ocorreu nos finais da década de 1940, quando foi criada a Associação de Crédito e Assistência Rural (ACAR) que foram os primeiros órgãos a elaborar planos de créditos a trabalhadores rurais. Já durante a década de 1960 com a fundação da ATER, foi possível buscar novas práticas de agricultura, buscando torná-la mais revolucionária na forma de se cultivar o solo, desde desenvolver novas técnicas de cultivo, utilização de maquinários nos sistemas agropecuários. Além disso a contribuição dos serviços de extensão rural, está cooperando para o desenvolvimento da agricultura familiar, disseminando conhecimentos e novas tecnologias através da assistência técnica e extensão rural gratuita através dos serviços públicos oferecidos pelos estados e municípios.