bluuebunny/crossref_metadata_2025_split huggingface dataset:
The pruitt‐inahara carotid shunt as an assisting tool to anastomose the arterial free flap pedicle to the internal carotid artery in the vessel‐depleted neck
Authors: Salgarello Marzia , Snider Francesco , Finocchi Valerio , Bussu Francesco , Paludetti Gaetano , Almadori Giovanni 
Published: February 2011

AbstractMicrovascular free tissue transfer in head and neck reconstruction requires suitable recipient vessels which are frequently compromised by prior surgery or radiotherapy to the neck. This article details a new technique of arterial free flap pedicle anastomosis to the internal carotid artery in a vessel‐depleted neck. A 63‐year‐old female was referred because of recurrence of squamous cell carcinoma of the tongue, which involved the left‐sided tongue base and pharynx with circumferential involvement of the homolateral external carotid artery. This artery and its branches were excluded as potential recipients. To close the defect after tumor excision, a free vertical rectus abdominis muscle arterial flap pedicle was anastomosed to the homolateral internal carotid artery with the help of a Pruitt‐Inahara outlying carotid shunt. The venous anastomosis was performed to the internal jugular vein. The VRAM flap survived without complications. This procedure is to be considered an alternative rescue technique for salvage reconstruction in vessel depleted necks. © 2011 Wiley‐Liss, Inc. Microsurgery, 2011.
Microvascular reconstructions of traumatic‐combined tissue loss at foot and ankle level
Authors: Battiston Bruno , Antonini Andrea , Tos Pierluigi , Daghino Walter , Massazza Giuseppe , Riccio Michele 
Published: February 2011

AbstractSevere injuries at foot and ankle level with loss of soft tissues and bone are often treated by means of amputation. The transfer of composite free flaps from various donor sites may provide anatomical reconstruction of the foot and ankle and function. Ten patients who sustained severe combined tissue injuries of the foot requiring reconstruction with composite free flaps were studied with a mean follow‐up of 3.4 years. A thorough clinical examination was performed, and gait analysis was carried out with kinetic and kinematic parameters. Bone integration and healing was observed with satisfactory foot morphology. All the patients returned to normal activities, although biomechanical gait analysis showed some functional disorders mainly in joint angular kinematics. Our results showed that microvascular flaps afford successful combined tissue reconstruction of the foot. © 2011 Wiley‐Liss, Inc. Microsurgery, 2011.
False aneurysm of the common digital artery. Is reconstruction with an arterial graft worth the efforts? A case report
Authors: Lucchina Stefano , Nistor Alexandru , Stricker Hans , Fusetti Cesare 
Published: February 2011

AbstractFalse aneurysms in the hand are rare. A false aneurysm of the common digital artery in the palm for the second and third finger is reported, illustrating our experience with arterial graft reconstruction after excision as a valid alternative surgical therapy to a vein graft, when ligation or end‐to‐end anastomosis are not indicated or feasible. The superficial palmar branch of the radial artery was chosen as donor vessel based on the similarity in vessel diameter and wall thickness to the common digital arteries. Ease of harvesting and performing the microvascular anastomosis using an arterial graft allows for a viable reconstruction after false aneurysm excision in the palm. © 2010 Wiley‐Liss, Inc. Microsurgery, 2011.
Coexpression and estrogen‐mediated regulation of TRPV6 and PMCA1 in the human endometrium during the menstrual cycle
Authors: Yang Hyun , Choi Kyung‐Chul , Hyun Sang‐Hwan , Jeung Eui‐Bae 
Published: February 2011

AbstractMaintenance of calcium balance in the uterus is essential for many of its functions, including embryo implantation. The plasma membrane Ca2+‐pumping ATPase proteins are encoded by four genes designated PMCA1‐4, and PMCA1 is expressed in the uterus of rats during the estrous cycle. Although transient receptor potential cation channel subfamily V, member 6 (TRPV6), has been detected in the human placenta, pancreas and the prostate gland, expression patterns of uterine TRPV6 and PMCA1 and their potential roles in the human endometrium remain to be elucidated. In the present study, the expression patterns of TRPV6 and PMCA1 were examined to predict their potential roles in the human endometrium during the menstrual cycle. Human classified endometrial tissues (total n = 40) were separated into three groups according to menstrual cycle phase: menstrual, proliferative (early‐, mid‐, late), and secretory phase (early‐, mid‐, late). The expression of TRPV6 and PMCA1 mRNA and protein in the uterine endometrium during the menstrual cycle increased by 1.5‐ to 1.8‐fold at the proliferative phase (early‐, mid‐, and late‐) in comparison to the other phases. Estrogen treatment caused a significant increase in TRPV6 and PMCA1 mRNA expression. Immunohistochemical analysis of the distribution of TRPV6 and PMCA1 in the uterus revealed that both proteins are abundantly expressed in the cytoplasm of endometrial and glandular epithelial cells during menstrual phases. Taken together, these results suggest that uterine expression of TRPV6 and PMCA1 may be involved in human reproductive function. Mol. Reprod. Dev. 78:274–282, 2011. © 2011 Wiley‐Liss, Inc.
Respiratory self‐gated multiple gradient recalled echo sequence for free‐breathing abdominal R2* mapping
Authors: Jin Ning , Zhang Zhuoli , Zhang Longjiang , Lu Guangming , Larson Andrew C. 
Published: February 2011

AbstractAbdominal effective transverse relaxation rate (R2*) mapping is critical for a wide range of applications. However, respiratory motion can lead to significant image quality deterioration and R2* overestimation. For this work, we explored the feasibility of combining respiratory self‐gating techniques with a multiple gradient‐recalled echo sequence for free‐breathing abdominal R2* measurements. In a series of eight normal volunteers, respiratory self‐gated–multiple gradient‐recalled echo methods effectively avoided motion artifacts to produce quantitative R2* measurements in liver, spleen, and kidneys that were comparable to R2* measurements produced while breath‐holding. Respiratory self‐gated–multiple gradient‐recalled echo methods demonstrated the potential to avoid the need for breath‐holding during abdominal R2* mapping. For clinical application, respiratory self‐gated–multiple gradient‐recalled echo approaches could be particularly useful for R2* measurements in those patients unable or unwilling to sustain sufficiently long breath‐holds to avoid motion artifacts. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.
Quantitative conductivity and permittivity imaging of the human brain using electric properties tomography
Authors: Voigt Tobias , Katscher Ulrich , Doessel Olaf 
Published: February 2011

AbstractThe electric properties of human tissue can potentially be used as an additional diagnostic parameter, e.g., in tumor diagnosis. In the framework of radiofrequency safety, the electric conductivity of tissue is needed to correctly estimate the local specific absorption rate distribution during MR measurements. In this study, a recently developed approach, called electric properties tomography (EPT) is adapted for and applied to in vivo imaging. It derives the patient's electric conductivity and permittivity from the spatial sensitivity distributions of the applied radiofrequency coils. In contrast to other methods to measure the patient's electric properties, EPT does not apply externally mounted electrodes, currents, or radiofrequency probes, which enhances the practicability of the approach. This work shows that conductivity distributions can be reconstructed from phase images and permittivity distributions can be reconstructed from magnitude images of the radiofrequency transmit field. Corresponding numerical simulations using finite‐difference time‐domain methods support the feasibility of this phase‐based conductivity imaging and magnitude‐based permittivity imaging. Using this approximation, three‐dimensional in vivo conductivity and permittivity maps of the human brain are obtained in 5 and 13 min, respectively, which can be considered a step toward clinical feasibility for EPT. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.
Motion correction using coil arrays (MOCCA) for free‐breathing cardiac cine MRI
Authors: Hu Peng , Hong Susie , Moghari Mehdi H. , Goddu Beth , Goepfert Lois , Kissinger Kraig V. , Hauser Thomas H. , Manning Warren J. , Nezafat Reza 
Published: February 2011

AbstractIn this study, we present a motion correction technique using coil arrays (MOCCA) and evaluate its application in free‐breathing respiratory self‐gated cine MRI. Motion correction technique using coil arrays takes advantages of the fact that motion‐induced changes in k‐space signal are modulated by individual coil sensitivity profiles. In the proposed implementation of motion correction technique using coil arrays self‐gating for free‐breathing cine MRI, the k‐space center line is acquired at the beginning of each k‐space segment for each cardiac cycle with 4 repetitions. For each k‐space segment, the k‐space center line acquired immediately before was used to select one of the 4 acquired repetitions to be included in the final self‐gated cine image by calculating the cross correlation between the k‐space center line with a reference line. The proposed method was tested on a cohort of healthy adult subjects for subjective image quality and objective blood‐myocardium border sharpness. The method was also tested on a cohort of patients to compare the left and right ventricular volumes and ejection fraction measurements with that of standard breath‐hold cine MRI. Our data indicate that the proposed motion correction technique using coil arrays method provides significantly improved image quality and sharpness compared with free‐breathing cine without respiratory self‐gating and provides similar volume measurements compared with breath‐hold cine MRI. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.
Safety of influenza and H1N1 vaccinations in patients with myasthenia gravis, and patient compliance
Authors: Auriel Eitan , Regev Keren , Dori Amir , Karni Arnon 
Published: February 2011

AbstractMyasthenia gravis (MG) exacerbations may be triggered by infections.In the winter of 2009/2010, the Israeli Ministry of Health recommended that each individual with a chronic condition be vaccinated against both the seasonal influenza and the H1N1 virus. We examined vaccination practices in 74 MG patients. Only 38 patients (51.4%) received the seasonal influenza vaccine, and 24 (32.4%) received the H1N1 vaccine. No exacerbation of MG was found, and therefore seasonal influenza and H1N1 vaccines seem to be safe in MG. Muscle Nerve, 2011
Nerve compression, membrane excitability, and symptoms of carpal tunnel syndrome
Authors: Han S. Eric , Lin Cindy S.‐Y. , Boland Robert A. , Kiernan Matthew C. 
Published: February 2011

AbstractIntroduction: In this study we investigated the changes in axonal excitability and the generation of neurological symptoms in response to focal nerve compression (FNC) of the median nerve in carpal tunnel syndrome (CTS). Methods: Sensory excitability recordings were undertaken in 11 CTS patients with FNC being applied at the wrist using a custom‐designed electrode. Results: During FNC, refractoriness increased significantly (62.4 ± 3.4%; P < 0.001), associated with a rapid reduction in superexcitability (16.9 ± 2.8%; P < 0.001) and sensory nerve action potential amplitude (SNAP) (32.4 ± 3.9%; P < 0.001), consistent with axonal depolarization. Associated with these changes, paresthesiae steadily increased throughout FNC, as did numbness. Reductions in SNAP amplitude and superexcitability developed more rapidly for CTS patients during FNC compared with controls, and these changes were associated with more marked symptoms. Conclusions: Axonal responses to compression are impaired in CTS. This may suggest a greater reliance on axonal membrane Na+/K+‐ATPase function. Muscle Nerve 44: 402–409, 2011
SPH truncation error in estimating a 3D derivative
Authors: Amicarelli Andrea , Marongiu Jean‐Christophe , Leboeuf Francis , Leduc Julien , Neuhauser Magdalena , Fang Le , Caro Joëlle 
Published: February 2011

AbstractFollowing the procedure proposed in Quinlan et al. (Int. J. Numer. Meth. Engng. 2006; 66:2064–2085) for a 1D generic derivative, a 3D formulation of the Smoothed Particle Hydrodynamics (SPH) truncation error (εT) has been derived and validated. We have then underlined the differences between traditional SPH simulations, which are not consistent, and estimations using renormalization, a first‐order consistency technique. The consistency order is here defined as the highest degree of a generic polynomial function, which can be exactly reproduced by an SPH approximation.Under the homogeneous conditions assumed in our analyses renormalization generally reduces the relative truncation error by 1 or 2 orders of magnitude, both at inner points and boundary locations. Due to renormalization the error tends to a lowest constant value as the kernel support size (h) goes to zero, while in general with no consistency the error behaves like 1/h. In contrast to formulations without any consistency estimations, using renormalization there is a weak dependence of the error on the absolute value of the displacement of the particles from their volume barycentre (δ). In addition, for simulations with renormalization, the best choice for the kernel function seems to be the closest to Dirac's delta, while for the ones with no consistency, the preferences are altered. Furthermore, we observe that renormalization reduces the number of neighbors that are necessary to obtain a discretization error that is negligible with respect to the integral error. Copyright © 2011 John Wiley & Sons, Ltd.
Ballistic performance study of fabric armor based on numerical simulations with multiscale material model
Authors: Xia Weijie , Adeeb Samer M. , Nadler Ben 
Published: February 2011

AbstractBased on a multiscale model for fabric materials, dynamic simulations of the fabric ballistic performance were implemented. Through parameter research, it was found that the ballistic performance and mechanical behavior of the fabric materials are determined by a combination of factors and conditions rather than by the material properties alone. The material mechanical properties reflect the inherent strength of the fabric; the fabric weaving structure, boundary conditions, material orientation, and projectile shape also play important roles and have a significant influence on the ballistic performance of the fabric.The multiscale material model incorporates not only the membrane‐like properties of the fabric but also the underlying weaving structure, yarn interaction, and yarn composition. The simulations results show good agreement with the experimental data. Various physical phenomena can be observed in the simulations, such as yarn decrimping, material anisotropy, and two types of damage modes. Copyright © 2011 John Wiley & Sons, Ltd.
From database to face‐to‐face —wateraid's donor development programme
Authors: Pugh Marcus , Young Jane 
Published: February 2011

AbstractThis paper was first presented at the Henry Stewart Conference, ‘Relationship marketing for charities: Latest thinking and best practice’, on 23rd February, 1996.The paper describes the implementation of the Donor Development Programme at WaterAid and the lessons learned during this process. The analogy of a courtship is used for the development of the relationship between the supporter and the charity.
Whatever happened to the pub crawl? — a change in attitude to charitable fundraising
Authors: Shaw Martin 
Published: February 2011

AbstractThis paper argues that there needs to he greater clarity in the role of today's charities and calls for structured research and evaluation of modern fundraising techniques and strategies, particularly to help smaller charities. It also blames the many councils of voluntary organisations and umbrella associations supporting the smaller charities for failing to provide adequate information and training in fundraising.
American arts service organisations: Conduits for millions in funding
Authors: Reiss Alvin H. 
Published: February 2011

AbstractAlthough national arts service organisations in the United States existed prior to the establishment of the National Endowment for the Arts in 1965, the real growth and development of the arts service field owes a large debt to the emergence of government as an official supporter of the cultural industry. As the number of arts organisations multiplied at a frightening pace throughout the mid 'sixties and early 'seventies, the need for concrete data and for new insights into funding and audience development techniques grew quickly. As the need for arts funding increased, private foundations felt a growing strain on their resources. Many larger foundations discovered that in order to make a significant impact with a far‐reaching programme in a key area of concern, involving scores of grantees, the logistics could be staggering. An answer to this problem lay in the use of conduits, as potential grant recipients that could best serve the programme's needs. In turning to national arts service organisations to help them administer some of their key programmes foundations found more than willing partners.The following paper surveys some of the interesting, cost‐effective and productive programmes that have linked foundations and arts service organisations to meet the needs of the arts industry.
Charity brands: A qualitative study of current practice
Authors: Tapp Alan 
Published: February 2011

AbstractA number of fundraising managers and directors of UK charities were interviewed with the objective of understanding to what extent branding was used in the sector, what development possibilities exist for commercial techniques in charities, and what the constraints may be on such practices.It was found that many charities already use day‐to‐day brand techniques, (without describing them as ‘branding’), but brand development work was scarce.Charities have a number of objectives competing with fundraising when considering their brand content. They must also satisfy the need to respect issues about how the cause itself is communicated, and possible needs to re‐educate the donor community or the public.One commercial practice in particular could be developed further in charity branding: this is the idea of using the personality of the charity itself as something with which donors could associate positively.
Database segmentation: An alternative to recency, frequency, value?
Authors: Lister John 
Published: February 2011

AbstractThis paper argues that recency, frequency, value (RFV), the engines of database segmentation in the voluntary sector, are by no means the only profitable approaches to database segmentation. The use of response models based on core statistical theorems offers an alternative to RFV that may be more discriminatory in targeting both those who are most likely to respond (the people we want to communicate with), and also those least likely to respond (the people we want to avoid).
Profiling the charity donor: A case study of the game conservancy trust
Authors: Sargeant Adrian 
Published: February 2011

AbstractThis paper identifies the key fundraising problems faced by the Came Conservancy Trust and describes the donor research that was undertaken in an attempt to resolve these key issues. A survey of 1,000 donors was undertaken and the respondents were profiled according to demographic variables and their response to 20 attitudinal statements. These statements were then subjected to a factor analysis to identify the underlying psychographic variables. Seven such variables were identified and subjected (along with a range of demographic variables) to a regression analysis with a view to identifying which of them would prove to be significant indicators of a propensity to donate larger sums to this organisation. A number of the psychographic factors were indeed found to be significant indicators of the level of support a particular donor might be predisposed to provide. In the light of these findings the paper concludes with a number of recommendations to the Trust for changes to its fundraising strategy.
Pathogenese, Klinik und Therapie der Virusgrippe. Vom harmlosen Infekt bis zur Intensivstation
Authors: Herold Susanne 
Published: February 2011

AbstractInfluenzaviren infizieren Epithelien des oberen Respirationstraktes und führen in der Regel zu unkomplizierten fieberhaften Infekten mit Allgemeinsymptomen und respiratorischen Beschwerden. Selten beobachtet man bei Influenza‐Infektionen eine rasche Virusausbreitung bis in die distalen Luftwege mit Beteiligung des Lungenparenchyms (Influenza‐Pneumonie), häufig gefolgt vom akuten Lungenversagen (ARDS) mit der Indikation zur maschinellen Beatmung oder extrakorporalen Oxygenierungsverfahren (ECMO). Bakterielle Superinfektionen mit Pneumokokken, Haemophilus influenzae und Staphylococcus aureus sind insbesondere bei beatmeten Patienten häufig. Infektionen mit pandemischen Influenza‐Viren (A/H1N1v) verliefen öfter schwer und zeigten eine besondere Häufung bei Kleinkindern und jungen Erwachsenen. Die Diagnostik der saisonalen Influenza wird in erster Linie klinisch gestellt; an Labortests stehen vor allem der Antigen‐Schnelltest und die PCR zur Verfügung. Die Therapie der unkomplizierten Grippe erfolgt meist symptomatisch, für schwere Verläufe besteht die Indikation zur antiviralen Therapie mit Oseltamivir oder Zanamivir. Die STIKO empfiehlt die jährliche Schutzimpfung für Risikogruppen.
Grippe‐Impfstoffe. Herstellung, Zulassung und Weiterentwicklung
Authors: Pfleiderer Michael 
Published: February 2011

AbstractInfluenza‐Impfstoffe sind seit vielen Jahrzehnten verfügbar. Ihr breiter Einsatz, der sich insbesondere auf die öffentlichen Impfempfehlungen stützt, hat sich jedoch erst in den letzten 15 bis 20 Jahren etabliert. Dies ist insbesondere aus den stetig steigenden Produktions‐ und Absatzzahlen ersichtlich. In dieser Zeit unterlag die Herstellung, Prüfung und Zulassung von Influenza‐Impfstoffen einer Reihe von bedeutenden Wandlungsprozessen, die in der Summe bewirkt haben, dass es jedes Jahr aufs Neue möglich ist, gut charakterisierte saisonale Influenza‐Impfstoffe rechtzeitig zur Verfügung zu stellen. Vor diesem wissenschaftlichen und regulatorischen Hintergrund haben sich auch geeignete Mechanismen zur Herstellung und Produktion pandemischer Influenza‐Impfstoffe herausgebildet. Bemerkenswert ist, dass Influenza‐Impfstoffe nach wie vor die einzige Virusimpfstoffklasse darstellen, die sich gegen höchst variable Erregerformen richtet. Die pharmazeutischen, logistischen und regulatorischen Hürden, die dabei zu meistern sind, wurden beschrieben. Als Konsequenz dieser Anstrengungen können Influenza‐Impfstoffe aller Art als höchst sichere Arzneimittel angesehen werden, deren Nutzen die möglichen Impfrisiken bei weitem überwiegt. Aufbauend auf unserem heutigen Wissen werden in den kommenden Jahren neue Influenza‐Impfstoffe hinzukommen, z.B. basierend auf lebend attenuierten Impfstämmen oder mit neuen Adjuvanzien versehen, durch die eine noch breitere Anwendung möglich sein wird. Dies kann natürlich nur auf der Grundlage einer umfangreichen klinischen Charakterisierung geschehen. Im positiven Falle mag es eines Tages wirklich möglich sein saisonale und pandemische Influenza‐Aktivitäten umfassender zu kontrollieren als diese derzeit der Fall ist.