bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Venous Thromboembolism on Mortality of Elderly Medicare Patients with Stage III Colon Cancer
Authors: Hanna Nader , Bikov Kaloyan A. , McNally Diane , Onwudiwe Nneka C. , Dalal Mehul , Mullins C. Daniel 
Published: July 2012

Abstract

Learning Objectives
After completing this course, the reader will be able to: Identify the prevalence of adjuvant chemotherapy utilization in elderly patients with stage III colon cancer.Discuss the prevalence and impact of venous thromboembolism in elderly patients with stage III colon cancer.Identify potential for development of a clinical trial to study the clinical benefit and impact on cancer-specific and all-cause mortality of thromboprophylaxis during adjuvant chemotherapy in elderly patients with stage III colon cancer.
CME This article is available for continuing medical education credit at CME.TheOncologist.com

Background.
The improvement in survival rates for patients with colon cancer has shifted the focus from examining cancer-specific mortality to exploring all-cause mortality. Adverse events such as venous thromboembolism (VTE) affect overall survival times and the net clinical benefit of cancer management strategies.

Methods.
This retrospective study used Surveillance, Epidemiology and End Results (SEER) Medicare data to examine VTE incidence and mortality rates for elderly patients with stage III colon cancer who were diagnosed in 2004 or 2005 and followed through 2007. The impact of VTE on mortality was estimated using multivariable Cox proportional hazards regression.

Results.
In all, 20.7% of 4,985 elderly patients with stage III colon cancer had clinically diagnosed VTE following diagnosis. All-cause mortality risk was higher for patients with a VTE diagnosis (hazard ratio [HR]: 1.15, 95% confidence interval [CI]: 1.04–1.27), greater comorbidity burden, more advanced tumor depth and nodal involvement within stage III, advanced age, and male sex; the risk was lower for patients treated with chemotherapy. VTE was associated with higher mortality hazards (HR: 1.41, 95% CI: 1.21–1.64) for patients treated with adjuvant chemotherapy but not for untreated patients.

Conclusions.
A new diagnosis of VTE significantly reduced survival rates for elderly patients with stage III colon cancer and further reduced survival rates for patients treated with chemotherapy. Improved prevention and management of VTE for elderly patients with stage III colon cancer who are at risk for VTE is warranted, particularly for patients treated with chemotherapy.
Progression of Periodontitis and Tooth Loss Associated with Glycemic Control in Individuals Undergoing Periodontal Maintenance Therapy: A 5‐Year Follow‐Up Study
Authors: Costa Fernando Oliveira , Miranda Cota Luís Otávio , Pereira Lages Eugênio José , Soares Dutra Oliveira Alcione Maria , Dutra Oliveira Peterson Antônio , Cyrino Renata Magalhães , Medeiros Lorentz Telma Campos , Cortelli Sheila Cavalca , Cortelli José Roberto 
Published: July 2012

Background: Prospective studies that investigated the influence of glycemic control in the progression of periodontitis and tooth loss during periodontal maintenance therapy (PMT) programs have not previously been reported. The aim of the present study is to evaluate associations between glycemic control status and progression of periodontitis and tooth loss among individuals during PMT.Methods: A total of 92 individuals, all recruited from a prospective cohort with 238 participants undergoing PMT, participated in this study. Diabetes control was assessed according to percentage of glycated hemoglobin (HbA1c). Individuals were matched for sex and smoking and were divided into three groups: 23 individuals with diabetes and poor glycemic control (PGC), 23 individuals with diabetes and good glycemic control (GGC), and 46 controls with no diabetes (NDC). Full‐mouth periodontal examination, including bleeding on probing (BOP), probing depth (PD), and clinical attachment level, was performed at all PMT visits during a 5‐year interval.Results: Progression of periodontitis and tooth loss were significantly higher among PGC compared to GGC and NDC. The final logistic model in the final examination included: 1) for the progression of periodontitis, HbA1c ≥6.5% (odds ratio [OR] = 2.9), smoking (OR = 3.7), and BOP in >30% of sites (OR = 4.1); and 2) for tooth loss, HbA1c ≥6.5% (OR = 3.1), smoking (OR = 4.1), and PD 4 to 6 mm in ≤10% of sites (OR = 3.3).Conclusions: PGC individuals, especially smokers, presented with a higher progression of periodontitis and tooth loss compared to NDC and GGC individuals. This result highlights the influence of glycemic control in maintaining a good periodontal status.
A novel biomimetic orthodontic bonding agent helps prevent white spot lesions adjacent to brackets
Authors: Manfred Lauren , Covell David A. , Crowe Jennifer J. , Tufekci Eser , Mitchell John C. 
Published: July 2012

Abstract

Objective:
To compare changes in enamel microhardness adjacent to orthodontic brackets after using bonding agents containing various compositions of bioactive glass compared to a traditional resin adhesive following a simulated caries challenge.

Materials and Methods:
Extracted human third molars (n  =  10 per group) had orthodontic brackets bonded using one of four novel bioactive glass (BAG)-containing orthodontic bonding agents (BAG-Bonds) or commercially available Transbond-XT. The four new adhesives contained BAG in varying percentages incorporated into a traditional resin monomer mixture. Teeth were cycled through low-pH demineralizing and physiologic-pH remineralizing solutions once each day over 14 days. Microhardness was measured on longitudinal sections of the teeth 100, 200, and 300 µm from the bracket edge and beneath the brackets, at depths of 25 to 200 µm from the enamel surface. Normalized hardness values were compared using three-way analysis of variance.

Results:
Significantly less reduction in enamel microhardness was found with the experimental adhesives at depths of 25 and 50 µm at all distances from the bracket edge. In all groups, there were no significant changes in enamel microhardness past 125-µm depth. Results varied with the different BAG-Bonds, with 81BAG-Bond showing the smallest decrease in enamel microhardness.

Conclusions:
The BAG-Bonds tested in this study showed a reduction in the amount of superficial enamel softening surrounding orthodontic brackets compared to a traditional bonding agent. The results indicate that clinically, BAG-Bonds may aid in maintaining enamel surface hardness, therefore helping prevent white spot lesions adjacent to orthodontic brackets.
Tortricidae (Lepidoptera) from the Tervuren Museum, 4: Enarmoniini, Eucosmini and Grapholitini
Authors: Razowski Józef 
Published: July 2012

Tortricidae (Lepidoptera) from the Tervuren Museum, 4: Enarmoniini, Eucosmini and Grapholitini
Eleven species are treated; one genus (Congancylis gen. n.) and nine species (Ancylis tryssops sp. n., Congancylis ghesquieri sp. n., Gypsonoma ngangaona sp. n., Charitostega achrosta sp. n., Melanodaedala magdalina sp. n., Cryptophlebia dolia sp. n., Grapholita mutsorae sp. n., G. niveosa sp. n., Grapholita ueleana sp. n.) are described as new.
Pratiques de littératie à l'école. Pour une approche ethnographique de la classe en deuxième année d'immersion en Colombie-Britannique(avec fonctionnement supplémentaire)
Authors: Moore Danièle , Sabatier Cécile 
Published: July 2012

RésuméÀ partir d'un corpus recueilli dans trois classes de deuxième année de l'école primaire en immersion française en Colombie-Britannique, l'article explore le concept de littératie(s) dans son articulation avec les notions de contexte et de culture éducative, et présente la méthodologie et les classes observées selon une perspective ethnographique. L'analyse des données insiste sur les pratiques de littératie dans les classes pour, dans sa conclusion, poser les jalons d'une réflexion qui envisage la question de l'agir professionnel et de la formation des enseignants. Cette étude met ainsi l'emphase sur le travail pédagogique des enseignants, en proposant une description minutieuse de l'éventail des pratiques de littératie qui font le quotidien des élèves et de leurs enseignants.
Vagus nerve stimulation for partial and generalized epilepsy from infancy to adolescence
Authors: Thompson Eric M. , Wozniak Susan E. , Roberts Colin M. , Kao Amy , Anderson Valerie C. , Selden Nathan R. 
Published: July 2012

Object
Vagus nerve stimulation (VNS) is approved by the FDA for the treatment of partial epilepsy in patients older than 12 years. Authors of the current study performed a large retrospective analysis and comparison of VNS outcomes in children with an age ≥ and < 12 years, including those with partial and generalized epilepsy.

Methods
A retrospective review of the records of pediatric patients (age < 18 years) who had undergone primary VNS system implantation between 2001 and 2010 by a single pediatric neurosurgeon was undertaken. Considered data included demographics, epilepsy type (partial vs generalized), seizure frequency, seizure duration, postictal period duration, and antiepileptic medication use.

Results
One hundred forty-six patients (49% female) were followed up for a mean of 41 months after VNS implantation. Thirty-two percent of patients had partial epilepsy and 68% had generalized epilepsy. After VNS system implantation, seizure frequency was reduced in 91% of patients, seizure duration in 50%, postictal period in 49%, and antiepileptic medication use in 75%. There was no significant difference in age, sex, or duration of follow-up according to epilepsy type. Neither was there any significant difference in seizure frequency reduction, seizure duration, postictal period, medication use, overall clinical improvement, or improvement in quality of life based on an age ≥ or < 12 years or epilepsy type.

Conclusions
Vagus nerve stimulation reduced both seizure frequency and antiepileptic medication use in the majority of pediatric patients regardless of sex, age cohort, or epilepsy type. Vagus nerve stimulation also reduced seizure duration and postictal period in approximately half of the pediatric patients. Contrary to expectation, children with partial epilepsy do not benefit from VNS at higher rates than those with generalized epilepsy.
Akteurskonstellation und Wissenskommunikation im Naturgefahrenmanagement der Schweiz
Authors: Bischof Nicole , Eppler Martin , Kienholz Hans 
Published: July 2012

The constellation of actors and the communication of knowledge in the management of natural hazards in Switzerland
Switzerland invests about CHF 2.9 billion a year in protection from natural hazards. In order to coordinate this protection and to plan strategies, the National Platform for Natural Hazards (Planat) has formulated a vision and a strategy for dealing with natural hazards with the purpose of implementing risk-based planning at a local level. This implementation process involves many protagonists as well as a great deal of expert knowledge and practical experience and it requires joint action. It can therefore be understood as a complex process of communication. Our research project goes into the questions of how this communication process works, which actors become involved and, at the end of the day, to what extent risk-based planning has already been implemented at a local level. In order to do this a transdisciplinary research approach was chosen. In this article we give an account of the results with regard to the constellation of actors. Whilst in general in communication analysis all three dimensions – contents, participants and sequence of events – are taken into consideration, we focussed in particular on the participants and in so doing investigated their roles and attitudes. The results of our qualitative survey demonstrate the interpretation of roles as well as the present constellation of actors in the management of natural hazards in Switzerland. The results confirm three findings: 1) that the transmission of knowledge is triggered off and fostered by exceptional occurrences and that 2) joint action and 3) the shared use of tools also lend their support to the transfer of knowledge.
Jalons pour une théorie critique du Manuel diagnostique et statistique des troubles mentaux (DSM)
Authors: Adam Christophe 
Published: July 2012

Publié par l’Association américaine de psychiatrie (APA), le Manuel diagnostique et statistique des troubles mentaux , mieux connu sous l’abréviation « DSM », s’impose comme l’instrument par excellence, tant dans le monde de la recherche scientifique que dans celui des pratiques cliniques. Depuis la première version de 1952 jusqu’à nos jours, le manuel a subi des révisions successives. La publication récente sur un site internet officiel du projet de la future nouvelle version (DSM-V), annoncée pour 2013, constitue un événement dit « historique » parce qu’il rendrait enfin transparent le processus de révision et s’ouvrirait ainsi à la critique du plus grand nombre, censée garantir la construction démocratique d’un manuel toujours plus rigoureux. Si la critique apparaît à la fois vive et polémiste dans le monde anglo-saxon, elle se montre beaucoup plus discrète dans le monde francophone alors que le manuel y est très utilisé et constitue indéniablement une référence incontournable. Le but de l’article est de poser les jalons d’une théorie critique du DSM, de ses conceptions et développements en vue d’un tant soit peu relativiser son caractère monopolistique.
Les mots pour (ne pas) le dire
Authors: Matonti Frédérique 
Published: July 2012

Résumé L'affaire Strauss-Kahn est une sorte de tremblement de terre. En France, il s'agit de la première arrestation d'un professionnel de la politique de premier plan pour crime sexuel. Plus encore, Dominique Strauss-Kahn aurait dû être le candidat des socialistes à l'élection présidentielle de 2012. L'affaire elle-même oppose un homme, blanc, riche et puissant à une femme noire et pauvre. Elle se déroule dans la société américaine dont les valeurs sont supposées profondément différentes des valeurs françaises quant à la sexualité et aux rapports genres. C'est pourquoi étudier les médias français du début de l'affaire du Sofitel jusqu'aux derniers développements de l'affaire du Carlton permet d'étudier les représentations françaises du viol, du harcèlement, du consenteme,nt et de la séduction. L'article s'appuie plus précisément sur trois types de récit (presse d'opinion ; presse people et presse féminine ; humoristes et imitateurs) sur des entretiens avec des journalistes et des directeurs de rédaction. Il montre avant tout la difficulté pour la plupart des médias à parler de viol ou de harcèlement pour qualifier le comportement présumé passé ou présent de Strauss-Kahn et en propose des explications autour des contraintes économiques, de la socialisation des journalistes et de leurs connaissances sur les études de genre et de race.
Deux critiques du consentement
Authors: Guillarme Bertrand 
Published: July 2012

Résumé La plupart des critiques du consentement admettent que le déterminisme causal ne remet pas en cause toute idée de liberté de choix. Au lieu de se focaliser sur le processus de délibération des agents, elles mettent l'accent sur deux caractéristiques du choix, dont l'absence fragilise son caractère libre, c'est-à-dire moralement valide. Certaines insistent sur l'importance des conditions du choix, en explorant la nuance que le langage ordinaire reconnaît entre « faire un choix » et « avoir le choix ». D'autres s'intéressent au contenu ou au résultat du choix, en faisant valoir que certaines options sont contradictoires avec la liberté « véritable » des personnes.
Différences linguistiques et dialectales dans la mise en place des procédures de segmentation de la parole
Authors: Nazzi Thierry , Goyet Louise , Sundara Megha , Polka Linda 
Published: July 2012

Résumé Cet article présente une synthèse d’études récentes portant sur la problématique de la segmentation précoce de la parole continue en mots, étape de l’apprentissage du langage constituant un prérequis pour l’acquisition du lexique. Après avoir exposé l’importance de cette question, nous présentons les recherches ayant exploré l’utilisation par les jeunes enfants de deux indices majeurs de segmentation : les indices distributionnels, les indices d’unités rythmiques. Le premier indice est considéré comme étant non spécifique à la langue parlée dans l’environnement de l’enfant, le deuxième comme différant selon les langues. Le premier indice prédit ainsi des trajectoires développementales de segmentation similaires à travers les langues, alors que le deuxième indice prédit différents types de trajectoires développementales en fonction du type de rythme de la langue acquise. Il apparaît que les capacités de segmentation émergent vers 8 mois et se développent dans les mois qui suivent, et que le poids des différents indices varie selon les langues, selon la période de développement, et probablement en fonction de différences dialectales au sein d’une même langue. Nous discuterons aussi du fait que la segmentation des formes sonores de mots nécessite vraisemblablement l’utilisation combinée de différents indices de segmentation, et ce dès le plus jeune âge. Pour finir, nous présenterons quelques pistes de recherche pour le futur.
Management of Hip Instability with a Cemented, Constrained Acetabular Component
Authors: Bakker-Dyos Josh , Moran Matthew 
Published: July 2012

We evaluated the use of a cemented constrained acetabular component to treat recurrent or potential instability after hip replacement. Over a seven year period, 109 patients who had undergone 110 operations were identified from hospital records. Patients were reviewed based on clinical and radiological follow-up. Post-operative function and quality of life was assessed using the Oxford Hip Score (OHS) and SF-12. From an original cohort of 109 patients, 9 patients were lost to follow up. Of the remaining 100 patients, the mean follow up was 2.9 years (SD±2 years). There were 4 failures, requiring 3 further revisions. The mean post-operative OHS was 33, SF-12 PCS 34 and SF12 MCS 52. 5-year survivorship was 90%. Cementing a constrained acetabular component provides satisfactory mid term results in patients at high risk of hip dislocation.
On the Hybrid of Fourier Transform and Adomian Decomposition Method for the Solution of Nonlinear Cauchy Problems of the Reaction-Diffusion Equation
Authors: Nourazar Salman , Nazari-Golshan Akbar , Yıldırım Ahmet , Nourazar Maryam 
Published: July 2012

The physical science importance of the Cauchy problem of the reaction-diffusion equation appears in the modelling of a wide variety of nonlinear systems in physics, chemistry, ecology, biology, and engineering. A hybrid of Fourier transform and Adomian decomposition method (FTADM) is developed for solving the nonlinear non-homogeneous partial differential equations of the Cauchy problem of reaction-diffusion. The results of the FTADM and the ADM are compared with the exact solution. The comparison reveals that for the same components of the recursive sequences, the errors associated with the FTADM are much lesser than those of the ADM. We show that as time increases the results of the FTADM approaches 1 with only six recursive terms. This is in agreement with the physical property of the density-dependent nonlinear diffusion of the Cauchy problem which is also in agreement with the exact solution.
The monotonic and very rapid convergence of the results of the FTADM towards the exact solution is shown to be much faster than that of the ADM
Synthese und Kristallstruktur des Komplexsalzes [Au(tBu2PH)2][HCl2] / Synthesis and Crystal Structure of the Complex Salt [Au(tBu2PH)2][HCl2]
Authors: Böttcher Hans-Christian , Mayer Peter , Schmidbaur Hubert 
Published: July 2012

Abstract
The synthesis and the characterization of the complex salt [Au(tBu2PH)2][HCl2] (2) resulting from the reaction of hydrogen tetrachloridoaurate(III) hydrate with tBu2PH in dichloromethane at room temperature is reported. Single crystals of 2 have been analyzed by X-ray crystallography: monoclinic, P21=c, Z = 12, a = 12:0805(3), b = 12:3729(4), c = 46:7506(13) Å ; ß = 90:948(2)°; V = 6986:9(3) Å3; T = 173(2) K. The hydrogen bihalide anions [HCl2]- fill the interstices between the large complex cations [Au(tBu2PH)2]+ in the crystal.
Coordination Chemistry of Perhalogenated Cyclopentadienes and Alkynes, XXIX. The Reaction of Ni(0) and Pt(0) Phosphane Complexes with Trichloroethene, Hexachloro- and Hexabromocyclopentadiene
Authors: Sünkel Karlheinz , Bernhartzeder Stefanie , Birk Uwe 
Published: July 2012

Abstract
Trichloroethene reacts with [Pt(PPh3)2(C2H4)] at first π to the complex [Pt(PPh3)2(η2-C2HCl3)] (1a), which isomerizes via the cis-isomer to the insoluble trans-[Pt(Cl)(η1-CH=CCl2)(PPh3)2] (2a). Both 1a and 2a react with PBu3 to the corresponding tributylphosphane complexes 1b and 2b, respectively. From the reactions of [Ni(PR3)2(C2H4)] (R = Me, Et, Bu) and C2HCl3 only the products of oxidative addition trans-[Ni(Cl)(η1-CH=CCl2)(PR3)2] (3a - c) can be isolated. Hexachlorocyclopentadiene and hexabromocyclopentadiene react with [Pt(PPh3)2(C2H4)] or [Ni(PR3)2(C2H4)] (R = Ph, Me) to give highly colored solutions.
An Efficient Route to 1,3,5-Triazido-2,4,6-tricyanobenzene
Authors: Becker Martin , Voss Karsten , Villinger Alexander , Schulz Axel 
Published: July 2012

Abstract
An efficient synthetic route starting from 1,3,5-trimethylbenzene is described for binary 1,3,5- triazido-2,4,6-tricyanobenzene. Besides 1,3,5-triazido-2,4,6-tricyanobenzene, all intermediates have been isolated and fully characterized.
Reactivity of Cu(I) Compounds towards Ethylenediamine and Dimethylformamide: Crystal Structure of CuCl(PiPr3)n (n=1, 2), CuX(PPh3)(en)2 (X=Cl, Br) and CuX(PPh3)(dmf)
Authors: Scharfe Sandra , Fässler Thomas F. 
Published: July 2012

Abstract
The synthesis of several phosphine Cu(I) complexes is reported, and their reactivity towards the solvents ethylenediamine (en) and dimethylformamide (dmf) has been investigated. CuX(PPh3) [X = Cl (1), Br (2)], CuCl(PCy3) (3) and CuCl(PiPr3)n [n = 1 (4), 2 (5)] were prepared according to adapted literature procedures. The complexes CuCl(PiPr3)n were obtained in crystalline form from a hexane solution at -70 °C and structurally characterized for n = 1 and 2. Copper halide complexes of PCy3 (3) and PiPr3 [n=1 (4)] gave colorless solutions in both en and dmf indicating the absence of Cu(II) ions. CuCl(PiPr3)2 is stable in dmf solutions. By contrast, the complexes CuX(PPh3) (X = Cl, Br) dissolve with blue color in en and with greenish-yellow color in dmf at higher temperatures under inert gas indicating a redox process affording Cu(II). At room temperature colorless crystals of CuX(PPh3)(en)2 [X = Cl (6), Br (7)] and CuX(PPh3)(dmf) [X = Cl (8), Br (9)] were isolated from the solutions and analyzed by single-crystal X-ray diffraction.
Reactivity of 4-Nitrosoanilines Towards Dimeric Halogenido-bridged Complexes of Iridium(III) and Rhodium(III) of the Type [(η5- C5Me5)MX2]2
Authors: Wirth Stefan , Lorenz Ingo-Peter 
Published: July 2012

Abstract
The synthesis, spectroscopic characterization and crystal structures of new C-nitrosoaryl complexes of iridium(III) and rhodium(III) are reported. The reactions of the μ2-halogenido-bridged dimers [(η5-C5Me5)IrX2]2 [X = Cl (1a), Br (1b), I (1c)] and [(η5-C5Me5)RhCl2]2 (2a) with N,N-dimethyl- (3) and N,N-diethyl-4-nitrosoaniline (4) yield the mononuclear complexes [(η5- C5Me5)MX2(3)] [M = Ir, X = Cl (5a), Br (5b), I (5c);M= Rh, X = Cl (7a)] and [(η5-C5Me5)MX2(4)] [M = Ir, X = Cl (6a), Br (6b), I (6c); M = Rh, X = Cl (8a)]. All new compounds were characterized by their melting points, NMR, IR and mass spectra as well as in selected cases by UV/Vis spectroscopy. The X-ray structure analyses revealed a slightly distorted pseudo-octahedral configuration (“three-legged pianostool”) and σ-N coordination of the C-nitroso ligand.