bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efektivitas Kombinasi Bakteri Streptomyces sp Dengan Pestisida Nabati Daun Sirih Dan Daun Kelakai Terhadap Penyakit Antraknosa Pada Cabai Hiyung
Authors: Erlangga Muhammad Dede , Budi Ismed Setya , Mariana Mariana 
Published: February 2025

Cabai merupakan komoditas yang mengalami fluktuasi harga akibat tingginya permintaan. Pada 2021 produksi cabai rawit di Indonesia turun 8,09% dibanding 2020. Penyakit antraknosa disebabkan oleh jamur Colletotrichum sp., dapat menurunkan produktivitas hingga 5-30%, bahkan menyebabkan gagal panen. Pengendalian hayati menggunakan Streptomyces sp. dan pestisida nabati seperti daun sirih dan daun kelakai adalah alternatif ramah lingkungan. Penelitian ini mengevaluasi efektivitas kombinasi tersebut terhadap antraknosa pada cabai hiyung. Hasil penelitian menunjukkan bahwa aplikasi bakteri Streptomyches sp., pestisida nabati Daun Kelakai, pestisida nabati Daun Sirih dan kombinasinya mampu menurunkan kejadian penyakit antraknosa dengan kejadian penyakit berkisar 15.05%-21.33% dibandingkan kontrol yang kejadian penyakitnya 33.24%. Hasil analisis efektivitas pengendalian penyakit terdapat 4 perlakuan yang cukup efektif yaitu Sirih 54.72%, Streptomyces sp. 46.48%, kombinasi Sirih dan Streptomyces sp. 43.65%, serta kombinasi kelakai dan Streptomyces sp 40.94%. Hasil pengamatan juga menunjukkan bahwa perlakuan pestisida nabati Sirih adalah perlakuan terbaik dalam menghasilkan tanaman tertinggi 30.56 cm dan meningkatkan berat basah dengan hasil 83.38 g, diikuti dengan perlakuan Kelakai yang juga menghasilkan hasil panen tertinggi 82.03 g. Selain itu, seluruh perlakuan yang diberikan mampu mempercepat umur pembungaan cabai 56.08-57.52 hari dibandingkan kontrol selama 58.28 hari.
Novel Approach to Enhancing Brain DHA Uptake: The Role of Nannochloropsis Microalgae Extract
Authors: Ma Kunpeng , Xie Shuhui , Zhang Ying , Liu Haixiang , Yu Wei , Chen Peihua 
Published: February 2025

Abstract

Docosahexaenoic acid (DHA) plays a pivotal role in sustaining the normal function of human brain and preventing metabolic and neurodegenerative disorders. Despite its significance, the bioavailability of DHA from current supplements is suboptimal due to limited uptake capacity of adult brain. Recent studies have highlighted the role of Mfsd2a transporter in facilitating brain uptake of DHA when esterified to lyso-phosphatidylcholine (LPC). Lyso-diacylglyceryltrimethylhomoserine (LDGTS), a betaine lipid that resembles LPC in structure and is abundant in Nannochloropsis microalgaeoil, presents a promising alternative for enhancing DHA uptake. This study aimed to examine whether LDGTS-containing microalgae oil can increase DHA level by the brain. We established 8 groups of mice fed with different lipid materials for comparison in addition to their regular diet. After 15 days of feeding, and tissue and organ samples of mice were collected for lipid extraction and fatty acid analysis. The mice fed a mixture of microalgae oil and triacylglycerol (TAG)-DHA showed a significant increase in DHA uptake in the brain compared to control. This effect was not observed when mice were administered with TAG-DHA alone, microalgae oil alone, or krill oil. The facilitation of DHA incorporation was accompanied by a notable enhancement of pathways related to cell growth and retinol metabolism in the brain, while pathways associated with cellular apoptosis and inflammation were downregulated. Thus, the inclusion of LDGTS-rich microalgae oil in DHA supplementation may offer a novel and effective strategy for improving the bioavailability of DHA in the brain.
Extravascular leakage of dexrazoxane during treatment of diffuse large B-cell lymphoma: A case report
Authors: Wakamiya Nao , Suzuki Masanori , Isezaki Tatsuya , Funakoshi Ryohkan 
Published: February 2025

Abstract

Background: Dexrazoxane is used to treat extravascular leakage of anthracycline antitumor agents, but its own extravascular leakage and management remain underreported. This case aimed to highlight both doxorubicin and dexrazoxane leakage during treatment for diffuse large B-cell lymphoma.
Case presentation: A 55-year-old man with diffuse large B-cell lymphoma developed doxorubicin leakage during R-CHOP therapy, which was treated with dexrazoxane. Subsequently, dexrazoxane leakage occurred, causing erythema and swelling. Topical clobetasol propionate was applied, leading to symptom resolution without necrosis. The patient successfully completed chemotherapy and achieved long-term remission.
Conclusions: This case report is one of the first to document the management of dexrazoxane extravascular leakage using topical steroids, effectively preventing severe outcomes. The findings suggest that topical steroids may be a desirable treatment approach for dexrazoxane leakage. Prompt intervention and interdisciplinary care contributed to the favorable outcome. This case highlights the need for further research and guideline refinement to optimize the management of inflammatory extravascular leakage.
Factors associated with homogenization management of outpatient services in multi-campus hospitals: a cross-sectional study based on Structural Equation Model
Authors: Wang Huilin , Wang Hao , Fang Hongjun , Guan Sinan , Ge Hourui , Yang Hongyan , Li Jing 
Published: February 2025

Abstract

Background: The multi-campus hospitals have become increasingly prevalent in China over the past few decades, however, how to improve the quality of service and better develop the multi-campus hospitals remain insufficiently understood in the literature. Patient satisfaction is an important indicator of the measurement of service quality. This study aimed to analyze the status of patient satisfaction and its key influencing factors, in order to provide relevant reference on the homogeneous management of service and differentiated strategies aiming at consistent quality in two campuses of a tertiary hospital in Beijing.
Methods: A total of 28155 surveys of outpatients who was willing to be investigated and had not been diagnosed with infectious diseases or in a state of emergency were conducted by a cross-sectional study in Beijing, China from January to April 2024. We use a 5-point likert scale with the choices of 1 (very dissatisfied), 2 (dissatisfied), 3 (Normal), 4 (satisfied), and 5 (very satisfied) to measure patient satisfaction. Statistical description, simple and multivariate logistic regression analysis were employed to analyze patient satisfaction and its associated factors. Additionally, the correlation behind the key influencing factors are revealed by the structural equation model.
Results: Results of this study showed that the waiting time, responsiveness of patientneeds, doctors’ diagnosis, advice on treatment plan, assistive medical technology, and attitude of doctors are important influencing factors on satisfaction in both campuses. Outpatient environment and hygiene situation of the toilet had a significant effect on the central campus, while guidepost, the service group and patients aged 0-44 are important to explain the differences in the new hospital campus.
Conclusion: For the management of multi-campushospitals, more attention should be paid to the waiting time, responsiveness of patientneeds, doctors’ diagnosis, advice on treatment plan, assistive medical technology service, and attitude of doctors in both campuses. In addition, hospital managers should focus on the service group as well as the initial settings in the new campus, while considering the substantial investment in infrastructure in the central campus.
Human Dignity as the Foundation of Peremptory Norms in International Law: Theoretical Considerations and Practical Implications
Authors: Karliuha Yelyzaveta 
Published: February 2025

Summary
The concept of human dignity receives considerable scholarly attention in international law. More often, however, such studies primarily focus on the genesis, definition, and functions of human dignity across various domains of international law, particularly within the ambit of international human rights law. This research seeks to inquire into a less-explored connection between human dignity and jus cogens. Such an attempt is made to elucidate the foundational character of human dignity for peremptory norms through the examination of travaux préparatoires of the 1969 Vienna Convention on the Law of Treaties, relevant treaties, as well as international and domestic jurisprudence. The overarching aim of this study is twofold: firstly, to enrich the discourse on human dignity by examining it as a general legal principle underpinning jus cogens, while illuminating its operational role within the international legal order; secondly, to provide further insights into the legal category of jus cogens by delineating the rationale for its existence and the foundations that support it.
2-D polar curves cloak structures for microwave applications
Authors: Raza Muhammad , Rybin Oleg , Rehman Najma Abdul , Shahid Reeha 
Published: February 2025

Abstract
This study investigates the design of electromagnetic devices, specifically wave rotators and cloaks, utilizing a polar rose-shaped structure. By applying the principles of transformation optics, the constitutive parameters – permittivity and permeability tensors – are analytically derived for transforming virtual space in cylindrical coordinates to physical space in Cartesian coordinates. Both integer and fractional indices of the rose configurations are considered, each yielding distinct electromagnetic properties. The analytical findings are validated and supported by numerical simulations conducted using COMSOL Multiphysics. The results highlight the tunability and adaptability of the proposed structures in controlling electromagnetic wave propagation, exhibiting rotational dynamics, cloaking, and absorption phenomena. Potential applications of these rose-shaped structures are briefly discussed.
Soft computing and eddy currents to estimate and classify delaminations in biomedical device CFRP plates
Authors: Versaci Mario , Laganà Filippo , Manin Laura , Angiulli Giovanni 
Published: February 2025

Abstract
This paper presents an approach based on eddy currents induced by suitable magnetic induction fields to test, estimate, and classify subsurface delaminations in Carbon Fibre Reinforced Polymer (CFRP) plates for biomedical devices. The two-dimensional maps obtained, characterised by high fuzziness, required the software development of a procedure based on a highly efficient fuzzy classifier that exploits fuzzy similarity computations with reduced computational load by collecting similar maps (deriving from equally similar defects) in specific defects. The hardware implementation of what is designed in software (plate-probe system) detects and evaluates the entity of the defects due to delaminations by a classification percentage comparable with the performances obtained from more sophisticated classifiers, providing a possible tool for evaluating the delaminations potentially useful to assess aircraft compliance with applicable safety standards.
Music Therapy in the Treatment: of People with Hearing Deficits: A Review of Selected Strategies
Authors: Surma Joanna 
Published: February 2025

Abstract
The paper deals with the question of music making in people with hearing deficits, showing the main advantages of such practice. It examines differences between ‘hearing’ in a medical sense and ‘musical hearing’ which is semantically much wider and involves different parts of the brain. Using various examples, the paper proves the possibility of music making even in the case of acute, bilateral or prelingual hearing impairment, but emphasises the necessity of Individualized Education Programme implementation to successfully face challenges posed by hearing deficits. The paper describes the main difficulties and challenges that deaf individuals face during the music learning process, and sums up strategies for musical pedagogy recommended in research studies since the second half of the twentieth century. Elements such as melodic patterns, rhythm and harmony are discussed. The teaching methodology presented in this paper focuses on multisensory approaches that may compensate for hearing loss, underlining such aspects as imagination, movement coordination, visual and haptic stimuli. Different types of hearing loss are presented, depending on their medical causes, hypoacusis level, onset time, and articulation ability in the context of music making. The article emphasises the beneficial role of active music-making for the patient’s well-being, especially for memory training, developing the emotional sphere, improvement of prosodic elements in speech, and tinnitus relief.
The Effectiveness of Ferric Chloride (FeCl₃) And Zeolite in Reducing Copper Heavy Metal and Dye Contaminants in Batik Industry Wastewater Treatment
Authors: Susilowati  , Romadoni Atika Wahyu Wulan , Ramadhan Dimas Anugrah , Jimmy Jimmy 
Published: February 2025

Objective: This study aims to evaluate the effectiveness of ferric chloride (FeCl₃) and zeolite as adsorbents in reducing copper content and dye pollutants in batik wastewater.

Theoretical Framework: Adsorption was chosen as the method for this study due to its suitability in addressing the challenges of batik wastewater treatment. Modifications in the preparation of adsorbents represent an effective approach for developing adsorption models and assessing their performance. The adsorbent used in this study is FeCl₃/zeolite, a composite material created through an impregnation process that combines ferric chloride (FeCl₃) and zeolite. The working mechanism of the FeCl₃/zeolite adsorbent involves coagulation and adsorption processes conducted within a laboratory-scale adsorption column. The effectiveness of the adsorbent is demonstrated by its significant ability to reduce heavy metal copper content and dye pollutants.

Method: The materials used for adsorbent preparation include zeolite and FeCl₃. Zeolite is activated using HCl to enhance its pore size. Subsequently, the zeolite is impregnated with FeCl₃ at a ratio of 3:1 for 3 hours under stirring at 250 rpm. The mixture is then filtered to separate the filtrate and precipitate. The precipitate is calcined at 200°C for 2 hours and characterized using SEM-EDX to analyze the adsorbent's properties. Finally, the prepared adsorbent is applied to treat batik wastewater.

Results and Discussion: The best results obtained from the study show that the FeCl₃/zeolite adsorbent achieved a maximum reduction in Cu content of 30% and a dye reduction of 27.86%. These results were achieved using 450 grams of adsorbent and an adsorption time of 10 minutes.

Research Implications: The results of this study are presented as data, which can be used as a reference or input for wastewater management, particularly for batik wastewater. Additionally, the findings can serve as a basis for environmental monitoring and control efforts.

Originality/Value: The study on adsorption of batik wastewater using FeCl₃/zeolite adsorbent combines coagulation and adsorption processes to reduce copper content and dye pollutants. Previous studies have not explored the use of activated zeolite impregnated with FeCl₃ as an adsorbent for reducing copper content and dye pollutants in batik wastewater.
Ethnomathematics: the Mathematical Knowledge of the Shintuya Native Community - Harakbut People of Madre de Dios, 2023
Authors: Pari Yony Raul Chambilla , Camargo Maria Isabel Puma , Huillca Ruth Nayda Sanchez , Ramos Carlos Bejar , Puma Luis Urbina 
Published: February 2025

Objective: The objective is to investigate the mathematical knowledge implicit in the cultural and pedagogical practices of the Shintuya Native Community, Harakbut People of Madre de Dios, in order to unveil the mathematical knowledge present in the culture and educational practices.

Theoretical Framework: The theories highlighted in ethnomathematics are: Ubiratan D'Ambrosio's Theory of Ethnomathematics, Gorman and Balter's Culturally Sensitive Parent Education, and Weinstein, Tomlinson and CurranView's Toward a Conception of Culturally Responsive Classroom Management.

Method: The methodology adopted comprised the qualitative approach, grounded theory and ethnographic method. Data were collected through interview, observation and documentary analysis.

Results and Discussion: The results revealed that mathematical knowledge is integrated in practical activities such as: land measurement, calculation of planting times and elaboration of patterns in handicrafts; promoting sustainable management of natural resources. This practical learning is transmitted by adults and elders in a pedagogical process based on observation and oral tradition, where young people apply concepts of quantity, form and proportion, while reinforcing values of respect and balance with the environment.

Research Implications: It reveals implications in areas such as: Education, revaluation of ancestral knowledge, intercultural education; Cultural, strengthening of cultural identity; Social, inclusion, equity and community development.

Originality/Value: This study contributes to the literature, providing new knowledge on the ethnomathematics of a cultural group that has been little studied. The relevance and value are evidenced in the rescue of ancestral mathematical knowledge, understanding of cultural diversity and design of pedagogical strategies.
Effectiveness of local hemostasis in nosebleeds in emergency medical care
Authors: Kadyshev V. A. , Chumakov P. L. , Goncharova N. A. , Bulychev S. N. , Voronkova N. Yu. , Sapozhnikov A. V. , Rokhmacheva Yu. A. , Tovmasyan A. S. 
Published: February 2025

The problem of achieving high-quality hemostasis in patients with spontaneous nosebleeds (NC) in emergency medical care (SMP) is still relevant.The purpose: to conduct a comparative assessment of the effectiveness of emergency medical care for patients over 18 years of age with anterior NC in the conditions of the NSR using a developed silicone single-chamber intra-nasal tampon with internal point glues, an intranasal (industrial production) balloon and a generally accepted method of tamponade using gauze turunda.Objectives: to analyze the prevalence and causes of NC in the structure of NSR calls in patients over 18 years of age in Moscow; to evaluate the effectiveness of the use of a developed medical device in patients with NC — a single-chamber intra-nasal tampon with internal point glues in comparison with the use of an intranasal balloon and gauze turunda.Materials and methods: An analysis of the structure of calls to patients with NC and an assessment of the effectiveness of stopping NC using an intra-nasal tampon with internal point glues, an intranasal balloon and a gauze turunda were carried out.The results of the study: It was revealed that in all the studied groups, NC occurred in the range from 28% to 37.3% in patients with hypertension who took anticoagulants/antiplatelet agents and in the range from 30.7% to 32% in patients with hypertension without taking anticoagulants/antiplatelet agents. It was found that in the first group of observations using a singlechamber intra-nasal tampon with internal point glues, the best characteristics of the efficiency of stopping NC were revealed: hemostasis was achieved in 92% of cases; less time spent on performing nasal tamponade was 1.6±0.5 min. and the time of onset of hemostasis was 1.2 min±0.3; pain was less pronounced in patients during nasal tamponade — 0.31±0.01 points; fewer repeated calls with recurrent NC (6.7% of cases) and repeated nasal tamponades (2.7% of cases); the call execution time was reduced by 9.5 min. — from 39.3±1.3 min. to 29.8±1.1 min.Conclusion: The data obtained as a result of the study indicate an improvement in the quality of medical care for patients with NC and allow us to recommend a promising expansion of the range of medical devices used to create high-quality hemostasis in NC at the prehospital stage.
Organization of emergency medical care and medical evacuation of the population of the Krasnodar Territory
Authors: Bagdasaryan A. S. , Pukhnyak D. V. , Linchenko S. N. , Sirunyants A. A. , Kamalyan Zh. A. , Onbysh T. E. , Gerashchenko E. V. 
Published: February 2025

Introduction. One of the directions of healthcare development today is the development and improvement of the emergency medical care system. The modern development of healthcare is based on the principles of medical and economic efficiency, characterized by increased requirements for the quality and timing of emergency medical care at its implementation stages, the introduction of high-tech diagnostic methods, reduction of the time for initiating etiopathogenetic treatment, and requires overall improvement of the emergency medical care system.The aim of the study was to assess the staffing of medical organizations providing emergency medical care in municipal entities of the Krasnodar Territory with emergency medical teams and medical transport, and to analyze the procedure for medical evacuation of patients from district central hospitals and medical organizations of cities to medical organizations in the city of Krasnodar.Materials and methods. Сall maps of emergency medical care organizations of the Krasnodar Territory, passports of medical organizations (district central hospitals, city central hospitals) of the region, stations, substations, and departments of emergency medical care were used in the study.Results and discussion. Ааssessed the level of staffing of emergency medical care organizations with emergency medical teams and specialized emergency medical teams, provision of medical organizations with medical transport. An analysis of the organization of the procedure for medical evacuation of patients from district central hospitals in rural areas to regional healthcare facilities was carried out.
Antiphospholipid syndrome associated with sicca syndrome
Authors: Kryeziu Avni , Kryeziu Shend , Berisha Fatlinda 
Published: February 2025

IntroductionAntiphospholipid syndrome (APS), or antiphospholipid antibody syndrome, is an autoimmune, hypercoagulable condition caused by antiphospholipid antibodies.AimThis case study aims to highlight diagnostic challenge of APS and its association with sicca syndrome.Case studyOur case is a female patient who was transferred to Rheumatology Clinic from the Central Intensive Care Unit (CICU) after being unconscious and on assisted breathing for 5 days. In 2006, she suffered a miscarriage and pulmonary thromboembolism. Since then, she has been under anticoagulant treatment. Clinical observation and positivity of laboratory tests such as anti Ro SSA, anti La SSB and Schrimer test confirmed us sicca syndrome. Positivity of lupus anticoagulant, anti-cardiolipin and anti-B2GP1 raise us suspicious about APS. The patient stayed in our clinic for approximately 10 days and based on the anamnesis, objective examination, laboratory and imaging tests, she was discharged home with the diagnosis of APS accompanied by sicca syndrome.Results and discussionAPS is an autoimmune condition, often challenging to diagnose, especially when it occurs in patients without sufficient symptoms and signs and without positivity in blood tests. The diagnosis of APS is often made through a combination of symptoms and laboratory tests.ConclusionsDiagnosing APS is not always easy, it is quite complex. Any case associated with spontaneous abortion and vascular accidents, without risk factors, should be suspected and investigated for APS. APS can often be secondary associated with other autoimmune diseases. Most often APS is associated with systemic lupus erythematosus, but in our case it is associated with sicca syndrome.