bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative risk estimation for large for gestational age using the area under the 100‐g oral glucose tolerance test curve
Authors: Kim Sollip , Min Won‐Ki , Chun Sail , Lee Woochang , Chung Hee‐Jung , Lee Pil Ryang , Kim Ahm 
Published: July 2009

AbstractWe devised a complementary quantitative method for gestational diabetes (GDM) that uses the area under the curve (AUC) of the results of the oral glucose tolerance test (OGTT), and evaluated its efficacy in predicting neonates that would be large for gestational age (LGA). The study subjects were 648 pregnant women. The AUC–OGTT (concentration × time) was calculated from the 100‐g OGTT results. The incidence of LGA according to each range of the AUC–OGTT was estimated and odds ratios were analyzed using multiple logistic regression analysis.The incidence of LGA increased with the AUC–OGTT value and was 0% for AUC<300, 7.8% for 300–400, 14.9% for 400–500, 20.8% for 500–600, and 45.5% for ≥600. The odds ratio of LGA increased by approximately two‐fold with an increase of 100 in the AUC–OGTT. The results indicated that the AUC–OGTT can be used to quantify the risk of LGA in GDM. The AUC–OGTT could complement a diagnosis of GDM using conventional diagnostic criteria. J. Clin. Lab. Anal. 23:231–236, 2009. © 2009 Wiley‐Liss, Inc.
Expression of CD4+CD25highCD127low/− regulatory T cells in transitional cell carcinoma patients and its significance
Authors: Zhu Xi , Ma Lin‐Lin , Ye Tian 
Published: July 2009

AbstractTo evaluate the expressions of CD4+CD25highCD127low/− regulatory T cells (Tregs) in peripheral blood from patients with transitional cell carcinoma (TCC) in urinary system, we investigated the proportion of Treg population in CD4+ T from 93 patients with TCC, 38 with benign urinary diseases, and 37 healthy subjects by using flow cytometric analysis and analyzing different clinicopathologic characteristics and the changes before and after operation. We found that the proportion of Treg in peripheral blood from patients with TCC was significantly increased as compared with the othertwo groups. There was a strong correlation between the proportion of Treg and tumor recurrence, quantity, lymph node metastasis (P<0.01), as well as pathological stage; no correlation was found between the proportion of Treg and clinical TNM stage (P>0.05). The proportion of Treg was also different before and after operation (P<0.05). This suggest that CD4+CD25+CD127low/− regulatory T cells may be responsible for immune suppression in TCC patients. The resection of tumor can decrease the proportion of Treg in peripheral blood. J. Clin. Lab. Anal. 23:197–201, 2009. © 2009 Wiley‐Liss, Inc.
Age‐dependent pattern of connexin43 expression in testes of European bison (Bison bonasus, L.)
Authors: Hejmej Anna , Kopera Ilona , Kotula‐Balak Malgorzata , Giżejewski Zygmunt , Bilińska Barbara 
Published: July 2009

AbstractMorphology and the expression of connexin43 (Cx43) was investigated in testes of immature, prepubertal, and adult European bison bulls by means of routine histology, immunohistochemistry, and Western blotting, respectively. Testes were collected from culled animals living in Bialowieza and Borecka Forests, Poland. Histological examination of testicular tissue of immature and prepubertal males revealed normal structure, whereas of adult individuals either normal testicular structure with advanced spermatogenesis or varying degrees of tubule and interstitial tissue abnormality were seen. Immunohistochemical studies revealed Cx43 signal mostly at Leydig cell membrane appositions. In testes of immature males heterogeneous staining was observed; its intensity markedly increased in prepubertal males reaching almost two times more intense staining in adults. Strong Cx43 signal between Leydig cells was also observed in testes with structural alterations; however, sporadically it was of weak linear pattern. In the tubules of the latter, the intensity of Cx43 staining was weak to moderate or it was even absent. Immunohistochemical qualitative analysis was confirmed by quantitative image analysis in which the staining intensity was expressed as relative optical density of diaminobenzidine deposits. Data from Western blot analyses confirmed the results obtained by immunohistochemistry; immunodetectable Cx43 protein as a band of 43 kDa was detected in all testes samples. Overall, the increase in Cx43 level in testes along the bison postnatal development may be capable of a better exchange of metabolites and coordinating Leydig cell activity during maturation. A relationship between homozygosity occurring in European bison and altered intercellular communication is suggested. J. Exp. Zool. 311A: 667–675, 2009. © 2009 Wiley‐Liss, Inc.
Structure and function of the maxillary nephridium of Lithobius forficatus (Chilopoda, Pleurostigmophora)
Authors: Rosenberg Jörg , Sombke Andy , Hilken Gero 
Published: July 2009

AbstractNotostigmophora and Lithobiomorpha are the only Chilopoda that have maxillary nephridia. The ultrastructure of the maxillary nephridium in Scutigera coleoptrata was described, but only light microscopic descriptions of this excretory organ of Lithobius forficatus are available. Therefore, we studied the ultrastructural organization of the maxillary nephridium of L. forficatus. In this species, the paired maxillary nephridium lies lateral to the pleuroventral longitudinal musculature in the region of the 1st and 2nd maxilla. The nephridium is partitioned in three compartments: a wide sacculus and a nephridial canal formed by a sac‐like labyrinth and a bean‐like utriculus. The sacculus opens with two different openings to the labyrinth. The labyrinth and the utriculus are connected by a short canal. Each nephridium opens to the exterior by two conducting canals. The lumen of the sacculus is lined by podocytes. The nephridial canal is formed by a high‐prismatic transport epithelium with a wide microvillar border and a high basal labyrinth. Only the epithelium of the utriculus is covered by a cuticle. Here, we compare the maxillary nephridia of L. forficatus (Pleurostigmophora) with that of Scutigera coleoptrata (Notostigmophora) in regard to their functional morphology, the mode of life of these species, and their excretory products. J. Morphol. 2009. © 2009 Wiley‐Liss, Inc.
HIV‐1 IN alternative molecular recognition of DNA induced by raltegravir resistance mutations
Authors: Mouscadet Jean‐François , Arora Rohit , André Joseph , Lambry Jean‐Christophe , Delelis Olivier , Malet Isabelle , Marcelin Anne‐Geneviève , Calvez Vincent , Tchertanov Luba 
Published: July 2009

AbstractVirologic failure during treatment with raltegravir, the first effective drug targeting HIV integrase, is associated with two exclusive pathways involving either Q148H/R/K, G140S/A or N155H mutations. We carried out a detailed analysis of the molecular and structural effects of these mutations. We observed no topological change in the integrase core domain, with conservation of a newly identified Ω‐shaped hairpin containing the Q148 residue, in particular. In contrast, the mutations greatly altered the specificity of DNA recognition by integrase. The native residues displayed a clear preference for adenine, whereas the mutant residues strongly favored pyrimidines. Raltegravir may bind to N155 and/or Q148 residues as an adenine bioisoster. This may account for the selected mutations impairing raltegravir binding while allowing alternative DNA recognition by integrase. This study opens up new opportunities for the design of integrase inhibitors active against raltegravir‐resistant viruses. Copyright © 2009 John Wiley & Sons, Ltd.
Epidemiologic risk profile of infection with different groups of human papillomaviruses
Authors: Chan Paul K.S. , Ho Wendy C.S. , Wong Martin C.S. , Chang Alexander R. , Chor Josette S.Y. , Yu Mei‐Yung 
Published: July 2009

AbstractThis study identified the age‐specific prevalence and epidemiologic risk profile for infection with different groups and species of human papillomaviruses (HPV). Structured interview and HPV testing were conducted for 2,604 Chinese women self‐referred for cervical screening. Independent risk factors for infection were identified by multiple logistic regressions. Overall, a major peak of HPV infection was observed at women aged 26–30 years, and a minor peak at 46–55 years. This pattern was observed for high‐risk, low‐risk, and alpha‐5/7/9 HPVs; but alpha‐3/6 HPVs showed peaks of similar magnitudes in young and older women. Independent risk factors for HPV infection (all types combined) included younger age (OR [95% CI] for >55 vs. ≤30 years = 0.22 [0.09–0.55]; 31‐45 vs. ≤ 30 years = 0.57 [0.33–0.99]), having ≥4 lifetime sexual partners (2.28 [1.06–4.88]), and smoking (2.24 [1.22–4.10]). Young age and smoking were the most consistent independent risk factors observed across different HPV groups. The risk profile for high‐risk HPV was similar to alpha‐5/7/9. Single‐type infection was associated with having more sexual partners, higher education level and oral contraception; whereas multiple‐type infection was associated with smoking. In conclusion, a U‐shaped age‐specific prevalence curve was observed for HPV infection overall, but with a different pattern for different HPV species. Different HPV groups showed variations in their risk profiles. These data are useful for formulating preventative strategy for HPV‐related diseases. Catch‐up vaccination program in Hong Kong should cover a wider age group as the first peak of infection occurred relatively late. J. Med. Virol. 81:1635–1644, 2009. © 2009 Wiley‐Liss, Inc.
Neural stimulation does not mediate attenuated vascular response in ACL‐deficient knees: Potential role of local inflammatory mediators
Authors: Miller Daniel , Salo Paul , Hart David A. , Leonard Catherine , Mammoto Takeo , Bray Robert C. 
Published: July 2009

AbstractChronic inflammation associated with osteoarthritis (OA) alters normal responses and modifies the functionality of the articular vasculature. Altered responsiveness of the vasculature may be due to excessive neural activity associated with chronic pain and inflammation, or from the production of inflammatory mediators which induce vasodilation. Using laser speckle perfusion imaging (LSPI), blood flow to the medial collateral ligament (MCL) of adult rabbits was measured in denervated ACL transected knees (n = 6) and compared to unoperated control (n = 6) and 6‐week anterial cruciate ligament (ACL)‐transected knees (n = 6). Phenylephrine and neuropeptide Y were applied to the MCL vasculature in topical boluses of 100 µL (dose range 10−14 to 10−8 mol and 10−14 to 10−9 mol, respectively). Denervation diminished vasoconstrictive responsiveness to phenylephrine compared to both control and ACL‐transected knees. Denervation minimally enhanced vascular responses to neuropeptide Y (NPY) compared to ACL deficiency alone, which nevertheless remained significantly diminished from control responses. To evaluate the potential role of inflammatory dilators in the diminished contractile responses, phenylephrine was coadministered with histamine, substance P, and prostaglandin E2. High‐dose histamine, and low‐dose substance P and PGE2 were able to inhibit contractile responses in the MCL of control knees. Excessive neural input does not mediate diminished vasoconstrictive responses in the ACL transected knee; inflammatory mediators may play a role in the deficient vascular responsiveness of the ACL transected knee. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:83–88, 2010
Geochemistry and extractable Fe and Al in cold‐temperature soils of northwestern Siberia
Authors: Mahaney William C. , Kalm Volli , Hancock Ronald G. V. , Michel Fred , Kapran Barbara 
Published: July 2009

AbstractThe concentrations of major, minor and trace elements in three Cryosols from northwestern Siberia were analysed to determine profiles of geochemical uniformity, element mobility and the release and build‐up of extractable Fe and Al. The scope of this study involves weathering processes over all or part of the Lateglacial to the Holocene Epoch (<10 ka) in a cold environment. Iron and Al extracts are investigated to elicit information regarding profile age and palaeoclimate. ‘Free’ iron (Fed) relative to total Fe increases in the Ah + Bw horizons compared with the lower horizons, where oxidation is weaker. Low total Fe reflects reworked felsic deltaic and shallow marine deposits from the Permian to the early Tertiary, thereafter emplaced by episodic flooding of glacial meltwater from the Arctic Urals and/or the Kara Sea Ice Sheet. Organically complexed Al (Alp), uniformly low in all soils, nevertheless shows trends indicating some downward movement, a rather unique occurrence in Arctic tundra soils. As indicated by the slow increase of oxihydrites, it may not be realistic to estimate the age of a profile by its physical characteristics. However, it appears possible to determine broad age ranges from the isotopic composition of water in soils. Copyright © 2009 John Wiley & Sons, Ltd.
Volatile compounds of experimental liver pâté from pigs fed conjugated linoleic acid in combination with monounsaturated fatty acids
Authors: Martin Diana , Antequera Teresa , Muriel Elena , Perez‐Palacios Trinidad , Ruiz Jorge 
Published: July 2009

AbstractBACKGROUND: Feeding conjugated linoleic acid (CLA) to pigs leads to CLA‐enriched meat products, which are of current interest owing to the potential health properties of CLA. However, dietary CLA increases the ratio of saturated to monounsaturated fatty acids (MUFA) in pig tissues. Combining CLA with high MUFA levels in pig diets may counteract this effect. Owing to the modification of fatty acid composition, variation in the volatile profile of derived meat products might be expected. The aim of the present work was to study the volatile profile, and its change during storage, of experimental liver pâté manufactured from pigs fed different levels of CLA and MUFA.RESULTS: Regardless of the CLA or MUFA level, 98 compounds were identified. Lower area units were observed for most branched aldehydes, ketones and alcohols and some furans, sulfur compounds and nitrogen compounds with increasing CLA and MUFA contents. Levels of nonanal, propan‐2‐one, dodecane, 2‐pentylfuran and ethylbenzene were higher in CLA pâtes. The effect of experimental diets on the change in volatiles during storage was not significant.CONCLUSION: Supplementation of pig diets with CLA isomers in combination with low or high MUFA levels seems to have a significant effect on the volatile profile of pork liver pâté. Copyright © 2009 Society of Chemical Industry
Ammonium‐Based Cellulose Solvents Suitable for Homogeneous Etherification
Authors: Köhler Sarah , Liebert Tim , Heinze Thomas 
Published: July 2009

AbstractNew ammonium‐based cellulose solvents with triethylmethylammonium‐ and tributylmethylammonium cations and carboxylate anions were synthesized and investigated as potential solvents for cellulose. Triethylmethylammonium formate was found to dissolve cellulose. Small amounts of formic acid may be used to adjust the melting point of the organic salt and can increase the dissolution velocity of cellulose. Carboxymethylation as a common etherification reaction was investigated in the new ammonium‐based system. The watersoluble carboxymethyl cellulose obtained, had a degree of substitution as high as 1.55. An unconventional pattern of substitution was accessible.magnified image
Dispersion of TiO2 Particles in PET/PP/TiO2 and PET/PP/PP‐g‐MA/TiO2 Composites Prepared with Different Blending Procedures
Authors: Li Wenjing , Karger‐Kocsis József , Schlarb Alois K. 
Published: July 2009

Abstract2 vol.‐% TiO2 particles were incorporated into PET/PP blends with and without MA‐grafted PP compatibilizer. During extrusion of the PET/PP/TiO2 composites the TiO2 particles migrated from the PP matrix to the PET‐dispersed phase irrespective of the blending route. For the PET/PP/PP‐g‐MA/TiO2 composites, however, the location of TiO2 depended on the blending sequence. The preferred location of the TiO2 nanoparticles was confirmed by SEM pictures taken from the chemically etched surface of the blends. The observed migration behavior was traced to differences in the interfacial tensions between TiO2 and PET and TiO2 and PP, and to TiO2 encapsulation in one of the blend components during the related blending procedure.magnified image
Coherent sequences of polynomial ideals on Banach spaces
Authors: Carando Daniel , Dimant Verónica , Muro Santiago 
Published: July 2009

AbstractThis article deals with the relationship between an operator ideal and its natural polynomial extensions. We define the concept of coherent sequence of polynomial ideals and also the notion of compatibility between polynomial and operator ideals. We study the stability of these properties for maximal and minimal hulls, adjoint and composition ideals. We also relate these concepts with conditions on the underlying tensor norms (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Universal abelian covers of superisolated singularities
Authors: Stevens Jan 
Published: July 2009

AbstractWe give explicit examples of Gorenstein surface singularities with integral homology sphere link, which are not complete intersections. Their existence was shown by Luengo–Velasco, Melle–Hernández and Némethi, thereby providing counterexamples to the universal abelian covering conjecture of Neumann and Wahl (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Characterization of a novel C8 phasic muscle stretch reflex
Authors: Baker Steven K. 
Published: July 2009

AbstractMuscle stretch reflexes (MSRs) are fundamental to the neurologic examination. Although the fifth, sixth, and seventh cervical roots have appropriate and easily elicited MSRs, the C8 level does not. The C8 reflex is obtained by tapping the thenar eminence, which produces flexion at the interphalyngeal joints of the fingers. To confirm that finger flexion represented an MSR, an externally triggered hammer‐skin contact set‐up was employed. Surface recording electrodes were placed at one third of the distance between the medial epicondyle and ulnar styloid. This montage produced distinct T‐waves with latencies compatible with a reflex arc. Normative data were collected for 75 healthy subjects (150 arms), including 15 from each of five age groups (20–29, 30–39, 40–49, 50–59, ≥60 years). Distance 1 (D1) was measured from the FPL to the C7 spinous process and distance 2 (D2) from C7 to the G1 electrode. A high median neuropathy abolished the T‐wave. A distal median nerve block at the carpal tunnel had no effect. Mean latencies (± SD) from the respective age groups were as follows: 21.73 ± 1.16 ms; 22.50 ± 1.70 ms; 22.19 ± 1.52 ms; 22.66 ± 2.13 ms; and 23.97 ± 1.91 ms. Reflex latencies significantly correlated with age (r = 0.33, P = 0.004), height (r = 0.51, P < 0.0001), and D1 + D2 or arc length (r = 0.74, P < 0.0001). This novel MSR is generated from the FPL tendon and stimulates contraction of the long finger flexors. It therefore represents a clinically useful C8 MSR. Muscle Nerve, 2009
Pericardial effusion with cardiac tamponade as a cardiac manifestation of duchenne muscular dystrophy
Authors: Lin Jainn‐Jim , Hwang Mao‐Sheng , Hsia Shao‐Hsuan , Chung Hung‐Tao , Chang Yu‐Sheng , Lin Kuang‐Lin 
Published: July 2009

AbstractDuchenne muscular dystrophy (DMD) is the most common hereditary neuromuscular disease in children. It is an X‐linked hereditary dystrophinopathy due to the absence of dystrophin. Its onset is often in early childhood and presents with proximal distribution of weakness and a progressive course. Cardiac involvement in DMD is common, and its onset is usually after the age of 10 years. The most common cardiac manifestations are a dilated cardiomyopathy and cardiac arrhythmia. However, pericardial effusion with cardiac tamponade is a very rare cardiac complication of DMD. We report a boy with DMD who initially presented with progressive dyspnea and an enlarged cardiac silhouette on chest radiography who subsequently developed a large pericardial effusion with cardiac tamponade. Early recognition of pericardial effusion with cardiac tamponade is important for institution appropriate therapy. Muscle Nerve, 2009
Dermatomyositis with inclusion body myositis pathology
Authors: Layzer Robert , Lee Han Sung , Iverson Donald , Margeta Marta 
Published: July 2009

AbstractThe pathogenic role of inflammation in inclusion body myositis (IBM) remains uncertain. A 63‐year‐old man developed a severe, rapidly progressive myopathy with clinical features typical of dermatomyositis (DM), but muscle pathology was typical of IBM. Treatment with prednisone and methotrexate resulted in complete remission of symptoms. Together with two similar cases reported previously, this case suggests that the inflammatory process of DM may trigger the pathologic changes of IBM. Muscle Nerve, 2009
Numerical solution of the Helmholtz equation in an infinite strip by Wiener‐Hopf factorization
Authors: Lucia Marcello , Maggio Fabio , Rodriguez Giuseppe 
Published: July 2009

AbstractWe describe an algorithm to compute numerically the solution of the Helmholtz equation: Δu + κu = f, u ∈ H01(S), where S is an infinite strip and κ a given bounded function. By using the finite difference approximation on the entire strip, we are led to solve an infinite linear system. When κ is constant the associated matrix is block Toeplitz and banded and the system can be solved using a Wiener‐Hopf factorization. This approach can also be adapted to deal with the case when κ is constant outside a bounded domain of the strip. Numerical results are given to assess the performance of our method. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 2010
He's homotopy perturbation method for solving Korteweg‐de Vries Burgers equation with initial condition
Authors: Inc Mustafa 
Published: July 2009

AbstractIn this article, we present the Homotopy Perturbation Method (Shortly HPM) for obtaining the numerical solutions of the Korteweg‐de Vries Burgers (KdVB) equation. The series solutions are developed and the reccurance relations are given explicity. The initial approximation can be freely chosen with possibly unknown constants which can be determined by imposing the boundary and initial conditions. The results reveal that HPM is very simple and effective. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 2010