bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of sulfate ester content in sulfated oligo‐ and poly‐saccharides by capillary electrophoresis with indirect UV detection
Authors: Kinoshita Mitsuhiro , Kakoi Naotaka , Matsuno Yu‐ki , Hayakawa Takao , Kakehi Kazuaki 
Published: July 2010

AbstractCarbohydrates having sulfate groups such as glycosaminoglycans and chemically synthesized sucrose sulfate show interesting and important biological activities. We adapted CE with indirect UV detection technique to the determination of sulfate ester in sulfated carbohydrates, which were previously hydrolyzed with HCl. The liberated sulfate ion was analyzed using a background electrolyte consisting of triethanolamine‐buffered chromate with hexamethonium bromide. Sulfate contents of glucose 3‐sulfate and sucrose octasulfate used as a model were in good agreement with theoretical values (accuracy, 95.9–96.7 and 97.4–101.9%, respectively), and relative standard deviation values run‐to‐run were 0.977 and 1.90%, respectively. We applied the method to the determination of the sulfate contents of some glycosaminoglycan samples and showed that the contents were in good agreement with those calculated from sulfur content. Copyright © 2010 John Wiley & Sons, Ltd.
A simple chromatographic method for determining norfloxacin and enoxacin in pharmacokinetic study assessing CYP1A2 inhibition
Authors: Kobayashi Toshimi , Homma Masato , Momo Kenji , Kobayashi Daisuke , Kohda Yukinao 
Published: July 2010

AbstractWe developed a simple assay method for the determination of serum and urine norfloxacin and enoxacin using reversed‐phase high‐performance liquid chromatography and perchloric acid precipitation for sample pre‐treatment. Optimized conditions can permit detection of norfloxacin and enoxacin in the same chromatogram, so either compound can be used as an internal standard for another determinant. Supernatants of the precipitated samples were analyzed by the octadecylsilyl silica‐gel column under ambient temperature and an ultraviolet wavelength of 272 nm. A mobile phase solvent consisting of 20 mm sodium dihydrogenphosphate (pH 3.0) and acetonitrile (85:15, v/v) was pumped at a flow rate of 1.0 mL/min. The calibration curves for norfloxacin and enoxacin at a concentration of 62.5–1000 ng/mL for serum and 250–4000 ng/mL for urine were linear (r > 0.9997). The recoveries of norfloxacin and enoxacin from serum and urine were >94% with the coefficient of variations (CV) <5%. The CVs for intra‐ and inter‐day assay of norfloxacin and enoxacin were <4.2 and <5.5%, respectively. This method can be applied to the pharmacokinetic study of norfloxacin and enoxacin after repeated administration to assess changes in CYP1A2 activity in healthy subjects. Copyright © 2010 John Wiley & Sons, Ltd.
ChemInform Abstract: Structural and Conductivity Studies of Y10‐xLaxW2O21.
Authors: Lashtabeg Anna , Bradley John , Dicks Andrew , Auchterlonie Graeme , Drennan John 
Published: July 2010

AbstractThe Y10‐xLaxW2O21 (x = 0—10) solid solution series is characterized by synchrotron XRD, TEM, and conductivity measurements.
ChemInform Abstract: Isolated ∞1[ZnPn2]4‐ Chains in the Zintl Phases Ba2ZnPn2 (Pn: As, Sb, Bi)—Synthesis, Structure, and Bonding.
Authors: Saparov Bayrammurad , Bobev Svilen 
Published: July 2010

AbstractThe three new title compounds are prepared by reaction of stoichiometric mixtures of the elements in a Pb flux (900—960 °C, 20 h, ≈100% yield).
ChemInform Abstract: Broensted Acid‐Catalyzed Cascade Cycloisomerization of Enynes via Acetylene Cations and sp3‐Hybridized C—H Bond Activation.
Authors: Jin Tienan , Himuro Masafumi , Yamamoto Yoshinori 
Published: July 2010

AbstractStarting materials (I),(III), and (V) are accompanied by minor amounts of the corresponding isomers possessing an exocyclic double bond.
ChemInform Abstract: Facile Oxidative Hydrolysis of Acetals to Esters Using Hypervalent Iodine(III)/LiBr Combination in Water.
Authors: Panchan Waraporn , Chiampanichayakul Supanimit , Snyder Deanna L. , Yodbuntung Siriporn , Pohmakotr Manat , Reutrakul Vichai , Jaipetch Thaworn , Kuhakarn Chutima 
Published: July 2010

AbstractThe reaction is general for the cyclic and noncyclic acetals, tolerating a wide range of aromatic and aliphatic substituents.
ChemInform Abstract: Chemo‐, Regio‐, and Stereoselective Synthesis of syn‐Aryl Glycol Monoesters from Aryl Olefins with Hydrogen Peroxide Catalyzed by RuCl3.
Authors: Zhang Yanqiao , Chu Guobiao , Cui Xiaoxue , Han Zhijie , Dou Daoke , Chen Yuanli , Yu Xiaosong , Li Chunbao 
Published: July 2010

AbstractIn the presence of aliphatic C—C double bonds, the aryl double bonds are selectively dioxygenated.
ChemInform Abstract: α‐Fluoroalkylation of Carbonyl Compounds Mediated by a Highly Reactive Alkyl‐Rhodium Complex.
Authors: Sato Kazuyuki , Yamazoe Satoshi , Akashi Yukiko , Hamano Tetsuya , Miyamoto Arisa , Sugiyama Shuhei , Tarui Atsushi , Omote Masaaki , Kumadaki Itsumaro , Ando Akira 
Published: July 2010

AbstractSilyl enol ethers of various carbonyl compounds are treated with diethylzinc and fluoroalkyl halides to afford the corresponding α‐fluoroalkylated carbonyl compounds.
ChemInform Abstract: Synthesis of the 1,2‐anti Type of 3E‐Alkene‐1,2,5‐triol Derivatives.
Authors: Kobayashi Yuichi , Takeuchi Akira , Hattori Hatsuhiko 
Published: July 2010

AbstractAn efficient method to obtain 3E‐alkene‐1,2,5‐triol derivatives with 1,2‐anti stereoselectivity from the corresponding 2Z,4E‐alkadienyl alcohols, which are synthesized by Ni‐catalyzed coupling reaction between lithium 1E‐alkenyl borates and 1‐halo‐1Z‐alken‐3‐ols such as (IX), is described.
ChemInform Abstract: An Alternative CuCl—Piperidine‐Catalyzed Oxidative Homocoupling of Terminal Alkynes Affording 1,3‐Diynes in Air.
Authors: Zheng Qingwei , Hua Ruimao , Wan Youzhi 
Published: July 2010

AbstractOxidative homocoupling of terminal alkynes can be carried out under air in the presence of CuCl—piperidine catalyst to give 1,3‐diynes (II), (IV) in high to excellent yields.
ChemInform Abstract: Tributyltin Hydride in NMP‐Promoted Reduction of Acid Chlorides to Aldehydes under Transition‐Metal‐Free Conditions.
Authors: Le Menez Patrick , Hamze Abdallah , Provot Olivier , Brion Jean‐Daniel , Alami Mouad 
Published: July 2010

AbstractA simple and general procedure uses Bu3SnH in NMP for the partial reduction of the acid chloride substrates.
ChemInform Abstract: Catalytic Asymmetric Addition of Arylboronic Acids to N‐Boc Imines Generated in situ Using C2‐Symmetric Cationic N‐Heterocyclic Carbenes (NHCs) Pd2+ Diaquo Complexes.
Authors: Liu Zhen , Shi Min 
Published: July 2010

AbstractThe reaction tolerates a variety of aromatic and heteroaromatic substituents on α‐carbamoyl sulfones and boronic acis.
ChemInform Abstract: Oxidative Esterification of Aldehydes with Alcohols and Phenols in Air.
Authors: Cheng Shuanghua , Chen Jiuxi , Gao Wenxia , Jin Huile , Ding Jinchang , Wu Huayue 
Published: July 2010

AbstractA new, metal‐free methodology for the oxidative esterification of aldehydes is developed.
ChemInform Abstract: Homocoupling of Arylboronic Acids and Potassium Aryltrifluoroborates Catalyzed by Protein‐Stabilized Palladium Nanoparticles under Air in Water.
Authors: Prastaro Alessandro , Ceci Pierpaolo , Chiancone Emilia , Boffi Alberto , Fabrizi Giancarlo , Cacchi Sandro 
Published: July 2010

AbstractThe palladium nanoparticles are stabilized primarily within the protein cavity of a highly thermostable Dps protein from the thermophilic bacterium Thermosynechoccus elongatus.
ChemInform Abstract: A Convenient Phosphoryloxylactonization of Pentenoic Acids with Catalytic Hypervalent Iodine(III) Reagent.
Authors: Zhou Zhong‐Shi , He Xue‐Han 
Published: July 2010

AbstractOptimized conditions including iodobenzene as the catalyst in combination with MCPBA as the terminal oxidant allow the preparation of various title compounds.
ChemInform Abstract: Catalytic Atom‐Transfer Radical Cyclization by Copper/Bipyridine Species Encapsulated in Polysiloxane Gel.
Authors: Motoyama Yukihiro , Kamo Kazuyuki , Yuasa Akihiro , Nagashima Hideo 
Published: July 2010

AbstractA novel polysiloxane gel encapsulating CuCl(bipy) is prepared and successfully applied in the radical cyclization reaction of halogenated acetamide derivatives.
ChemInform Abstract: Imidazolethiones: Novel and Efficient Organocatalysts for Asymmetric Friedel—Crafts Alkylation.
Authors: Liang Xianrui , Fan Jiaoyang , Shi Fei , Su Weike 
Published: July 2010

AbstractThe TFA salts IDT and IDC are synthesized and successfully employed in the reaction of pyrroles with α,β‐unsaturated aldehydes.
ChemInform Abstract: Regioselective Amination of 3‐Bromoindolylmaleimide with Amines.
Authors: Jiang Di‐Fa , Yang Yan‐Wu , Shao Zhi‐Yu , Zhao Sheng‐Yin 
Published: July 2010

AbstractTitle compounds (I) are subjected to the regioselective amination with amines (II) to provide maleimide derivatives (III) or (IV) depending on the amount of (II) and the conditions used.
ChemInform Abstract: One‐Pot Approach for the Stereoselective Synthesis of Spirocyclopropyl Oxindoles from Isatins and Arsonium Salts.
Authors: Yu Haigang , Liu Ying , Zhang Hui , Chen Jie , Deng Hongmei , Shao Min , Ren Zhongjiao , Cao Weiguo 
Published: July 2010

AbstractThe trans‐products are obtained in high yields under mild conditions.
ChemInform Abstract: Tricyclic‐Isoxazolidine Analogues via Intramolecular 1,3‐Dipolar Cycloaddition Reactions of Nitrones.
Authors: Saubern Simon , Macdonald James M. , Ryan John H. , Woodgate Ruth C. J. , Louie Theola S. , Fuchter Matthew J. , White Jonathan M. , Holmes Andrew B. 
Published: July 2010

AbstractThe process is applied to the preparation of a variety of isoxazolidines.
ChemInform Abstract: Synthesis of Triazolo Indazolones Using 3D Mesoporous Aluminosilicate Catalyst with Nanocage Structure.
Authors: Chari M. Adharvana , Karthikeyan G. , Pandurangan A. , Naidu T. Siddulu , Sathyaseelan B. , Zaidi S. M. Javaid , Vinu A. 
Published: July 2010

AbstractThe three‐component cyclocondensation affords the biologically important heterocyclic skeleton in good to excellent yields.
ChemInform Abstract: Synthesis of Pyrazolopyridine 3‐Carboxylates by Friedlaender Condensation.
Authors: Toche Raghunath B. , Bhavsar Dinesh C. , Kazi Muddassar A. , Bagul Sandeep M. , Jachak Madhukar N. 
Published: July 2010

AbstractThe 5‐amino‐4‐formyl pyrazole (IV) is utilized as key intermediate for the synthesis of a series of fused heterocycles.
ChemInform Abstract: Synthesis of (Purin‐6‐yl)methylphosphonate Bases and Nucleosides.
Authors: Hasnik Zbynek , Pohl Radek , Hocek Michal 
Published: July 2010

AbstractMichaelis—Becker reaction of the mesylate (II) and Pd‐catalyzed cross‐coupling of 6‐iodopurines (IV) with zinc iodide derived from (V) offer efficient approaches to (purin‐6‐yl)methylphosphonates.
ChemInform Abstract: Synthesis of a Versatile 2 (1H)‐Pyrazinone Core for the Preparation of Tissue Factor‐Factor VIIa Inhibitors.
Authors: Jones Darin E. , South Michael S. 
Published: July 2010

AbstractA general method for the preparation of the target compounds (VII), consisting of the selective hydrolysis and N‐alkylation as key steps, is developed.
ChemInform Abstract: A Novel Three‐Component One‐Pot Reaction Involving β‐Naphthol, Aldehydes, and Urea Promoted by TMSCl/NaI.
Authors: Sabitha Gowravaram , Arundhathi K. , Sudhakar K. , Sastry B. S. , Yadav J. S. 
Published: July 2010

AbstractA novel multicomponent one‐pot reaction to 1,2‐dihydro‐1‐arylnaphtho[1,2‐e][1,3]oxazin‐3‐one derivatives (IV) is presented.
ChemInform Abstract: An Efficient One‐Pot Three Component Synthesis of 1,2‐Dihydro‐1‐arylnaphtho[1,2‐e][1,3]oxazine‐3‐ones Using Montmorillonite K10 under Solvent Free Conditions.
Authors: Kantevari Srinivas , Vuppalapati Srinivasu V. N. , Bantu Rajashaker , Nagarapu Lingaiah 
Published: July 2010

AbstractThe known heterocyclic system (IV) is obtained employing a three‐component, one‐pot procedure in the presence of montmorillonite K10 clay as Lewis acid.
ChemInform Abstract: Synthesis of Polyazamacrocycles Comprising 6,6′‐Diamino‐2,2′‐bipyridine Moieties via Pd‐Catalyzed Amination.
Authors: Averin Alexei D. , Uglov Alexei N. , Buryak Alexei K. , Bessmertnykh Alla G. , Guilard Roger , Beletskaya Irina P. 
Published: July 2010

AbstractA new family of macrocyclic ligands incorporating one or two fluorescent diaminobipyridine moieties is synthesized by the Buchwald—Hartwig amination reaction.
ChemInform Abstract: Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae)
Authors: Mbaze Meva'a Luc , Lobe Songue Jules , Wansi Jean Duplex , Kamdem Waffo Alain Francois , Dongo Etienne , Ngando Mpondo Theophile , Sewald Norbert 
Published: July 2010

Abstractisolation and structure elucidation of the new acridone alkaloid citropsine A (I) together with thirteen known compounds
ChemInform Abstract: PMP (p‐Methoxyphenyl), a Versatile N‐Protective Group in the Synthesis of Chiral Amines and Amino Acids
Authors: Alsters Paul L. , Verkade Jorge M. M. , Rutjes Floris P. J. T. , Quaedflieg Peter J. L. M. 
Published: July 2010

AbstractReview: 40 refs.
Extrapolation of the W7‐X Magnet System to Reactor Size
Authors: Schauer F. , Wobig H. , Egorov K. , Bykov V. , Köppen M. 
Published: July 2010

AbstractThe fusion experiment Wendelstein 7‐X (W7‐X), presently under construction at the Greifswald branch institute of IPP, shall demonstrate the reactor potential of a HELIAS stellarator. HELIAS reactors with three, four and five periods have been studied at IPP since many years. With a plasma axis induction of 5 T, corresponding to about 10 T maximal induction at the coil, it was shown that such reactors are feasible. Now the possibility is being investigated to increase the conductor induction up to the 12 T – range, corresponding to > 5.5 T at the plasma axis. This improves the stellarator confinement properties but does not change the basic physics with respect to the previously analyzed machines. In particular the 5periodic HELIAS type, HSR5, is considered which evolves from W7‐X by linear scaling of the main dimensions by a factor of four.Recent progress in superconductor technology and the extensive development work performed for ITER are taken into account. The latter is particularly relevant since by coincidence the circumferences of the HSR5 and the ITER toroidal field coils are practically the same. For the presented 12 T reactor version, the HSR50a, also the conductor and structural requirements are comparable to the corresponding ITER specifications. Therefore, advantage can be taken of these similarities for the stellarator reactor magnet design.The input was provided by the new code “MODUCO” which was developed for interactive coil layout. It is based on Bézier curve approximations and includes the computation of magnetic surfaces and forces (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Magnetic Diagnostics for Equiibrium Reconstruction at W7‐X
Authors: Geiger J. , Endler M. , Werner A. 
Published: July 2010

AbstractFor W7‐X a set of magnetic diagnostic coils is foreseen to assess plasma properties such as toroidal net current and energy content for real‐time monitoring and also for equilibrium reconstruction. In addition to the set of full Rogowski‐Coils, diamagnetic coils and saddle loops, a set of segmented Rogowski‐Coils is envisaged to access profile information. The planned scheme of equilibrium reconstruction is described and the status of the analysis of the magnetic diagnostics is presented and its prospects are discussed. It is found that the plasma energy may be retrieved with good accuracy. However, the recovery of profile information shows limited accuracy based on the statistical analyses and modeling done so far (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Configuration Space Control for Wendelstein 7‐X
Authors: Dodson T. , Baylard Ch. , Hartmann D. , Greve H. , Herold F. 
Published: July 2010

AbstractThe Wendelstein 7‐X stellarator (W7‐X) is a superconducting fusion experiment presently under construction at the Greifswald branch of the Max‐Planck‐Institut für Plasmaphysik in Greifswald, Germany. W7‐X is a device with extreme geometrical complexity due to the close‐packing of components inside the cryostat and their complex three‐dimensional shapes. The task of the Configuration Space Control department is to ensure that these components do not collide with each other under the defined set of configurations such as during assembly, at cool down, or during operation at various coil currents, among others. To fulfill this task, sophisticated tools and procedures were developed and implemented within the realm of a newly founded division that focuses on design, configuration control, and configuration management. This paper will discuss the Configuration Space Control process, explore the advantages to the project resulting from the process, and demonstrate its application in the analysis of the cryogenic cooling pipes of Module 5 (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Synthesis, Structural, Redox and Mössbauer Characterization of Four‐Electron‐Oxidized Tetrakis(cyclohexyl)iron(II)porphodimethene with Different Axial Ligations (Eur. J. Inorg. Chem. 22/2010)
Authors: Bhattacharya Dibyendu , Sarkar Sabyasachi 
Published: July 2010

AbstractThe cover picture shows induced electron‐transfer reactions with I2 or Br2 as external oxidant, FeIII as internal oxidant, and coordinated porphyrinogen as internal reductant. As a result of this simultaneous metal‐ and ligand‐based redox reaction, the square‐planar iron(III) complex is transformed to a square‐pyramidal iron(II) complex, and the tetraanionic porphyrinogen ligand is oxidized to the neutral porphodimethene. The iron(III/II) redox potential of porphodimethene complexes are more positive than that of the heme cofactor. The large quadruple splitting with large isomeric shift indicates a high‐spin state (S = 2) for the [LΔΔFeII–I]+ cation. Details are discussed in the article by S. Sarkar et al. on p. 3429 ff.
Osteopontin presentation affects cell adhesion—Influence of underlying surface chemistry and nanopatterning of osteopontin
Authors: Malmström Jenny , Christensen Brian , Lovmand Jette , Sørensen Esben S. , Duch Mogens , Sutherland Duncan S. 
Published: July 2010

AbstractOsteopontin is a promising coating material for biomaterials, being important both in remodeling and formation of mineralized tissue and in immunological responses. We have investigated cell attachment to osteopontin adsorbed at different surface chemistries (NH2, COOH, CH3, and bare gold) and to osteopontin presented as a nanopattern of 50 nm protein patches separated by a nonadhesive background. MDA‐MB‐435 cells adhere well to osteopontin presented at the hydrophilic chemistries (NH2, COOH, and gold) suggesting that osteopontin is presented in a functional form on these surfaces. On the amine surface, the cell attachment appears partly driven by electrostatic attraction between the positively charged substrate and the negatively charged cell membrane, whereas the spreading of the cells depends on the specific interaction with osteopontin presented at the surface. Significantly, fewer cells adhere to osteopontin presented at the methyl‐terminated hydrophobic surface and the cells are less spread. On the nanopatterned osteopontin, only a very low number of cells adhered and those few attached cells showed an elongated morphology with few adhesion points to the surface. This indicates that the adhesive patches are not large enough to support stable focal contacts. The good cell attachment and spreading on the hydrophilic surfaces holds promise for osteopontin as a future coating for biomaterials. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Osteoconductive effects of calcium phosphate glass cement grafts in rabbit calvarial defects
Authors: Lim Hyun‐Chang , Sohn Joo‐Yeon , Park Jung‐Chul , Um Yoo‐Jung , Jung Ui‐Won , Kim Chang‐Sung , Lee Yong‐Keun , Choi Seong‐Ho 
Published: July 2010

AbstractCalcium phosphate glass (CPG) is well‐documented alloplastic bone graft material. The objective of this study was to evaluate the osteoconductive effect of newly developed calcium phosphate glass cement (CPGC) in rabbit calvarial defects. Three circular defects (8 mm diameter) were created on the rabbit calvarium. One defect was filled with biphasic calcium phosphate (BCP group) and one defect was filled with CPGC (CPGC group). The remaining defect was not filled as the control. Histologic and histometric analysis were performed at four and eight weeks following the implantation of materials. One‐way ANOVA method was used to evaluated the significance between three groups (p < 0.05). The CPGC group did not show a statistical difference in new bone area compared with the control at all healing periods, but the bone formation rate of CPGC seemed to increase between four and eight weeks. This suggests the bone formation rate of CPGC is initially slow, but increases at a specific time, showing the possibility of greater bone formation with time. The resorption rate of CPGC was greater than BCP. Within the limits of this study, CPGC demonstrated good space maintaining capacity and had an osteoconductive effect, suggesting it could be successfully used to improve bone formation capacity. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010.
Post‐transcriptional regulation of the DUSP6/MKP‐3 phosphatase by MEK/ERK signaling and hypoxia
Authors: Bermudez Olga , Jouandin Patrick , Rottier Juliette , Bourcier Christine , Pagès Gilles , Gimond Clotilde 
Published: July 2010

AbstractDUSP6/MKP‐3 is a cytoplasmic dual‐specificity phosphatase specific for the MAP kinases ERK1/2. Previous data have shown that the MEK/ERK axis exerts a retro‐control on its own signaling through transcriptional and post‐translational regulation of DUSP6. We first confirm the key role of MEK/ERK in maintaining the levels of dusp6 mRNA, while PI3K/mTOR, p38 MAPK, and JNK signaling pathways had no significant effects. We further show that regulation of dusp6 mRNA stability plays a critical role in ERK‐dependent regulation of dusp6 expression. Luciferase reporter constructs indicated that MEK/ERK signaling increased the half‐life of dusp6 mRNA in a 3′untranslated region (3′UTR)‐dependent manner. In addition, hypoxia, a hallmark of tumor growth, was found to increase both endogenous levels of dusp6 mRNA and the stability of the luciferase reporter constructs containing its 3′UTR, in a HIF‐1‐dependent manner. Nevertheless, a basal ERK activity was required for the response to hypoxia. Finally, Tristetraprolin (TTP), a member of the TIS11 CCCH zinc finger protein family, and PUM2, an homolog of drosophila pumilio, two proteins regulating mRNA stability reduced the levels of endogenous dusp6 mRNA and the activity of the dusp6/3′UTR luciferase reporter constructs. This study shows that post‐transcriptional regulation is a key process in the control of DUSP6 expression. J. Cell. Physiol. 226: 276–284, 2010. © 2010 Wiley‐Liss, Inc.