bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel implantation model for evaluation of bone healing response to dental implants: the goat iliac crest
Authors: Schouten C. , Meijer G. J. , Van Den Beucken J. J. J. P. , Spauwen P. H. M. , Jansen J. A. 
Published: March 2010

AbstractObjectives: Despite the availability of numerous animal models for testing the biological performance of dental and orthopedic implants, the selection of a suitable model is complex. This paper presents a new model for objective and standardized evaluation of bone responses to implants using the iliac crest in goats.Material and methods: The feasibility of the iliac crest model regarding anatomy and implant positioning was determined using two cadaveric specimens and the bone structure was evaluated and compared with that of the goat femoral condyle. Additionally, the validity of the model was tested by performing an in vivo study.Results: By means of a rather simple, safe, fast and reproducible surgical procedure, the iliac crest in goats could be approached and allowed the implantation of maximally five dental implants per iliac crest. Because of the bilateral implantation possibility, statistical comparisons between groups on either side of the goat could be performed, resulting in a high statistical power, and hence a reduction in the number of animals required to obtain significant data.Conclusions: In terms of surgical approach, anatomy and implant positioning, the iliac crest is the preferred model over the femoral condyle model. The iliac crest implantation model is suitable for evaluation of the osteogenic response to bone implant materials and represents a justified and deliberate alternative to the already existing animal models. To cite this article:
Schouten C, Meijer GJ, van den Beucken JJJP, Spauwen PHM, Jansen JA. A novel implantation model for evaluation of bone healing response to dental implants: the goat iliac crest. Clin. Oral Impl. Res. 21, 2010; 414–423. doi: 10.1111/j.1600‐0501.2009.01872.x
Bone substitute as an on‐lay graft on rat tibia
Authors: Truedsson A. , Wang J.‐S. , Lindberg P. , Gordh M. , Sunzel B. , Warfvinge G. 
Published: March 2010

AbstractObjectives: To investigate the capacity of Cerament®, an injectable bone substitute, to guide bone generation from a cortical surface.Materials and method: Cerament® was applied to the cortical surface of rat tibiae and investigated histologically after 3, 6 and 12 weeks, using a procedure similar to that performed in sham‐operated rats.Results: In both groups, the thickness of the bone cortex increased significantly from 473±58 μm (mean±SD) at day 0 to 1193±255 μm (Cerament®) and 942±323 μm (sham) after 3 weeks. In the Cerament® group, the new bone thickness remained constant (1258±288 μm) until the end of the experiment at 12 weeks, while the sham group demonstrated a return to initial cortical thickness (591±73 μm) at 12 weeks. The newly formed bone in the Cerament® group was highly trabecular after 3 weeks but attained a normal trabecular structure of the cortex after 12 weeks.Conclusion: Cerament® may guide bone generation from an intact cortical bone surface. Although bone remodeling speed may differ between rats and humans, our study indicates that Cerament® may become a useful alternative to autologous bone, both to fill defects and to increase bone volume by cortical augmentation. To cite this article:
Truedsson A, Wang J‐S, Lindberg P, Gordh M, Sunzel B, Warfvinge G. Bone substitute as an on‐lay graft on rat tibia. Clin. Oral Impl. Res. 21, 2010; 424–429. doi: 10.1111/j.1600‐0501.2009.01875.x
ORIGINAL RESEARCH—EPIDEMIOLOGY: The HSDD Registry for Women: A Novel Patient Registry for Women with Generalized Acquired Hypoactive Sexual Desire Disorder
Authors: Rosen Raymond C. , Connor Megan K. , Maserejian Nancy N. 
Published: March 2010

ABSTRACT

Introduction
Hypoactive sexual desire disorder (HSDD) is a clinically challenging disorder in women. Little is known about the natural history of the disorder and long-term consequences. A longitudinal registry can address these needs.

Aim
To design and implement a registry study of HSDD in women to characterize the natural history of HSDD and current treatment practices.

Methods
A longitudinal multicenter registry study has been initiated at clinical sites across the United States. A total of 1,500 women (approximately 1,000 premenopausal, 500 postmenopausal) with clinically-diagnosed HSDD, confirmed by the Decreased Sexual Desire Screener, will be recruited over 24 months at up to 40 clinical sites. Participants will be followed with in-clinic or remote, computer-assisted follow-up. Data from the initial implementation phase was analyzed to assess feasibility of the protocol. A qualitative substudy (N=40) was conducted to assess content validity of the participant questionnaire.

Main Outcome Measures
The primary outcome measure for the Registry study is a patient-based global impression of change in HSDD. Secondary outcome measures are derived from two sources: (i) self-administered questionnaire completed by the participant, and (ii) medical history review completed by the clinician. The questionnaire includes validated measures of sexual function, quality of life, relationship factors, and physical and mental health, as well as newly developed questions on treatments and medications.

Results
As of February 12, 2009, 290 women (209 premenopausal, 81 postmenopausal) had been recruited from 15 clinical sites. Results of the initial implementation phase and qualitative substudy on the participant questionnaire show that the Registry protocol is highly feasible and the questionnaire consisting of previously validated scales and selected new items has high content validity.

Conclusions
As the first longitudinal registry study in female sexual dysfunction, the HSDD Registry will contribute to a broader understanding of the impact and treatment needs of women with clinically diagnosed HSDD.
Renunciation and Non‐Renunciation in Indian Films
Authors: Jain Pankaj 
Published: March 2010

AbstractRenunciation is one of the most widely studied subjects among Indic traditions. The image of a half‐naked ascetic with a stick in one hand and a begging bowl in other has captured the attention of scholars more often than the mundane householder. Whereas the ascetic captured the imagination with his (and sometimes her) individualistic spirit rebelling against the maligned caste hierarchy, the householder has been seen as a poor creature living a routine life according to the rules dictated by the caste (varna) and the stage in life (ashrama). In this article, I review several films to analyze the portrayal of ascetics and householders, but cannot claim that the review is encyclopedic because there are so many films with variations on this theme. All of the films introduced here were made by Indian filmmakers except for two Hollywood films,1The Householder (1963) and Siddhartha (1972), that were filmed in India with an Indian cast and story.
Visual Culture and American Religions
Authors: Schwain Kristin 
Published: March 2010

AbstractScholarship on the visual culture in American religions has flourished in the past three decades. Scholars from myriad disciplines have generated essays, monographs, and edited volumes that examine everything from fine art paintings to popular prints, church architecture to yard shrines, and folk art to graphic novels. In this essay, I provide an abbreviated explanation for the explosion of scholarship on visual culture and American religions in the 1980s and 1990s to highlight prominent approaches to the subject in contemporary scholarship. Then, I outline a few of the major themes that stimulate the scholarly field, including popular religion, consumption, cross‐cultural encounters, sacred space, modern and postmodern art, and dress. Finally, I consider challenges faced by contemporary scholars in developing and strengthening this interdisciplinary area of inquiry.
Pentecostal and Charismatic Christianity in South Africa and Zimbabwe: A Review
Authors: Ganiel Gladys 
Published: March 2010

AbstractPentecostal/charismatic Christianity is the fastest‐growing religion in southern Africa. This article explores its social and political roles, drawing primarily on examples from South Africa and Zimbabwe to illuminate wider trends across the continent. It considers the main competing assessments of Pentecostal/charismatic Christianity in Africa: (1) it is dominated by the ‘prosperity gospel’ and therefore stunts real economic growth and development; (2) it is primarily an apolitical faith that distracts people from their suffering; and (3) it is a Western import that disables the development of African cultures. It concludes that Pentecostal/charismatic Christianity in South Africa and Zimbabwe has included all of these elements. But recent research indicates that Pentecostal/charismatic Christianity is increasingly a socially and politically active religion that is surprisingly well‐placed to meet people’s economic and material needs, to empower people to participate in civic and public life, and to promote reconciliation between previously opposing groups.
Photophysics of Halogenated Fluoresceins: Involvement of Both Intramolecular Electron Transfer and Heavy Atom Effect in the Deactivation of Excited States
Authors: Zhang Xian‐Fu , Zhang Iris , Liu Lihong 
Published: March 2010

AbstractThe fluorescence quantum yield (Φf), fluorescence lifetime (τf), intersystem crossing quantum yield (Φisc) and redox potentials of seven halogenated fluoresceins in their dianion forms were measured and compared in methanol to get a deep insight into the effect of halogeno atoms on their photophysics. It is found that the heavy atom effect alone cannot explain the experimental results, as (1) Φf for chlorinated dyes exceeds that of fluorescein and close to unity, (2) the sum of Φf and Φisc for brominated and iodinated xanthene dyes is remarkably less than unity. The observations can be rationalized by the involvement of intramolecular photoinduced electron transfer, in which the benzoate acts as the electron donor while the xanthene moiety is the acceptor. The more negative reduction potential of excited singlet state for chlorinated fluoresceins results in their much smaller ket, and hence higher Φf.
Biochemical Imaging of Human Atherosclerotic Plaques with Fluorescence Lifetime Angioscopy
Authors: Thomas Patrick , Pande Paritosh , Clubb Fred , Adame Jessie , Jo Javier A. 
Published: March 2010

AbstractA prototype angioscopy system with fluorescence lifetime imaging microscopy (FLIM) capabilities was built and applied for biochemical imaging of human coronary atherosclerotic plaques. The FLIM angioscopy prototype consisted of a thin flexible angioscope suitable for UV‐excited autofluorescence imaging, and a FLIM detection system based on a pulse sampling approach. The angioscope was composed of an imaging bundle attached to a gradient index objective lens and surrounded by a ring of illumination fibers (2 mm outer diameter, 50 μm spatial resolution). For FLIM detection based on the pulse sampling approach, a gated‐intensified charge‐couple device camera (200 ps temporal resolution) was used. Autofluorescence was excited with a pulsed UV laser (337 nm) and FLIM images were acquired at three emission bands (390/40 nm, 450/40 nm, 550/88 nm). The system was characterized on standard fluorophores and then used to image postmortem human coronary arteries. The FLIM angioscope allowed us to distinguish elastin‐dominant plaques (peak emission at 450 nm, ∼1.5 ns lifetimes) from collagen‐dominant plaques (peak emission at 390 n, ∼2–3 ns lifetimes) based on their intrinsic fluorescence spectral and lifetime differences. This study demonstrates the potential of FLIM angioscopy for biochemical imaging of human coronary atherosclerotic plaques.
Novel Surfactant‐like Hypocrellin Derivatives to Achieve Simultaneous Drug Delivery in Blood Plasma and Cell Uptake
Authors: Zhang Yang , Song Liming , Xie Jie , Qiu Haixia , Gu Ying , Zhao Jingquan 
Published: March 2010

AbstractWater‐soluble derivatives of hypocrellins can be safely delivered in blood plasma but lose their photodynamic activity in vivo due to poor cell uptake, while hydrophobic derivatives retaining their activity may aggregate in the blood plasma and block vascular networks. Considering both drug delivery and biological activity, surfactant‐like hypocrellin B (HB) derivatives, sodium 12‐2‐HB‐aminododecanoate (SAHB) and sodium 11,11′‐5,8‐HB‐dimercaptoundecanoate (DMHB), were first designed and then synthesized in the current work. Both SAHB and DMHB were photoactive, generating free radicals and reactive oxygen species, as confirmed by EPR and chemical measurements. Most importantly, DMHB was not only readily soluble, allowing preparation of an intravenous injection solution at a clinically acceptable concentration, but it was also more photodynamic therapy (PDT) active to human breast carcinoma MCF‐7 cells than its parent HB under irradiation. The photodynamic activity was exactly identical to the 1O2 quantum yield and was not reduced by the improved water solubility, suggesting an independent hydrophilicity or lipophilicity. To our knowledge, this is a new strategy that possesses general significance for converting hydrophobic photosensitizers into clinically usable PDT drugs.
Calibration Estimation in Survey Sampling
Authors: Kim Jae Kwang , Park Mingue 
Published: March 2010

Summary Calibration estimation, where the sampling weights are adjusted to make certain estimators match known population totals, is commonly used in survey sampling. The generalized regression estimator is an example of a calibration estimator. Given the functional form of the calibration adjustment term, we establish the asymptotic equivalence between the functional‐form calibration estimator and an instrumental variable calibration estimator where the instrumental variable is directly determined from the functional form in the calibration equation. Variance estimation based on linearization is discussed and applied to some recently proposed calibration estimators. The results are extended to the estimator that is a solution to the calibrated estimating equation. Results from a limited simulation study are presented.
On the Decomposition by Subgroups of the Gini Index and Zenga's Uniformity and Inequality Indexes
Authors: Radaelli Paolo 
Published: March 2010

Summary Besides a brief historical outline of the Gini index decomposition proposals, we compare, in a subgroups framework, the decompositions of the Gini index and of the uniformity and inequality indexes recently proposed by Zenga. The two decompositions follow a similar scheme: in both cases the overall index can be at first expressed as a weighted average of convenient “cross” measures, with their own interpretation, and afterwards it is decomposed into a within and a between term by merely distinguishing measures evaluated within the same subgroup from the ones regarding different subgroups. This procedure does not depend on an a priori definition of the within or the between term and allows their contribution to be naturally evaluated preserving the structure of the index itself. In the last section the two decompositions are applied to the Italian net household wealth provided by the 2006 central Bank of Italy sample survey on household budgets.
A Review of Hot Deck Imputation for Survey Non‐response
Authors: Andridge Rebecca R. , Little Roderick J. A. 
Published: March 2010

Summary Hot deck imputation is a method for handling missing data in which each missing value is replaced with an observed response from a “similar” unit. Despite being used extensively in practice, the theory is not as well developed as that of other imputation methods. We have found that no consensus exists as to the best way to apply the hot deck and obtain inferences from the completed data set. Here we review different forms of the hot deck and existing research on its statistical properties. We describe applications of the hot deck currently in use, including the U.S. Census Bureau's hot deck for the Current Population Survey (CPS). We also provide an extended example of variations of the hot deck applied to the third National Health and Nutrition Examination Survey (NHANES III). Some potential areas for future research are highlighted.
Steroid injection in addition to macular laser grid photocoagulation in diabetic macular oedema: a systematic review
Authors: Steijns Daan , Duijvesz Diederick , Breedijk Marja A. , Van Der Heijden Geert J. M. G. 
Published: March 2010

Abstract.Objectives:  This study aimed to evaluate the evidence for the effects of steroid injection in addition to macular laser grid (MLG) photocoagulation versus those of MLG photocoagulation alone on visual acuity (VA) in patients with diabetic macular oedema (DMO).Methods:  An extensive literature search in Medline (PubMed), Experta Medica (EMBASE) and the Cochrane Library (CENTRAL) using synonyms for MLG photocoagulation, steroid injection and DMO found 181 articles. Of the articles that met selection criteria, three studies in which patients receiving MLG photocoagulation were randomized to additional pretreatment with steroids provided the best available evidence. In addition to VA, central foveal thickness (CFT) was measured at baseline and at 6 months in all three studies.Results:  Two studies, with total populations of 73 and 42 eyes, respectively, reported no additional effect of steroid injection on VA. One study, with a total of 41 eyes, reported a beneficial effect of pretreatment with steroids on VA of − 0.21 ETDRS logMAR units. All three studies reported larger reductions in CFT in eyes pretreated with steroids, the smallest of which was 64 μm.Conclusions:  Although there is a greater reduction in CFT in eyes pretreated with steroids, this does not consistently result in higher VA. The literature search does not provide sufficiently strong evidence to recommend steroid injection before MLG photocoagulation in DMO.
Structural biomass partitioning in regrowth and undisturbed mesquite (Prosopis glandulosa): implications for bioenergy uses
Authors: ANSLEY R. JAMES , MIRIK MUSTAFA , CASTELLANO MICHAEL J. 
Published: March 2010

AbstractHoney mesquite (Prosopis glandulosa Torr.) which grows on grasslands and rangelands in southwestern USA may have potential as a bioenergy feedstock because of existing standing biomass and regrowth potential. However, regrowth mesquite physiognomy is highly different from undisturbed mesquite physiognomy and little is known regarding growth rates and structural biomass allocation in regrowth mesquite. We compared canopy architecture, aboveground biomass and relative allocation of biomass components in regrowth (RG) trees of different known ages with undisturbed (UD) trees of similar canopy height to each RG age class. RG trees in most age classes (2–12 years old) had greater canopy area, leaf area, basal stem number, twig (<0.5 cm diameter) mass and small stem (0.5–3 cm diameter) mass than UD trees of the same height. Large stem (>3 cm diameter) mass was similar between RG and UD trees in all height classes. Ages of UD trees were determined after harvest and further comparisons were made between age, canopy structure and biomass in RG and UD trees. Relationships between age and total mass, age and height, and age and canopy area indicated a faster growth rate in RG than in UD trees. Large stem mass as a percentage of total tree mass accumulated more rapidly with age in RG than UD trees. Leaf area index and leaf : twig mass ratio were maintained near 1 in all RG and UD trees. Regrowth potential may be one of the most important features of mesquite in consideration as a bioenergy feedstock.
Identification of neoplastic cells in blood using the Sysmex XT‐2000iV: a preliminary step in the diagnosis of canine leukemia
Authors: Gelain Maria Elena , Rossi Gabriele , Giori Luca , Comazzi Stefano , Paltrinieri Saverio 
Published: March 2010

Background: Classification of leukemias requires specialized diagnostic techniques. Automated preliminary indicators of neoplastic cells in blood would expedite selection of appropriate tests.Objective: The objective of this study was to assess the capacity of the Sysmex XT‐2000iV hematology analyzer to identify neoplastic cells in canine blood samples.Methods: Blood samples (n=160) were grouped into 5 categories: acute leukemia (n=30), chronic leukemia (n=15), neoplasia without blood involvement (n=41), non‐neoplastic reactive conditions (n=31), and healthy dogs (n=43). WBC counts, WBC flags, scattergrams, percentages of cells with high fluorescence intensity, and percentages of cells in the lysis‐resistant region were evaluated alone or in combination to establish a “leukemic flag.” Sensitivity, specificity, negative (LR−) and positive (LR+) likelihood ratios, and the number of false‐negative (FN) and false‐positive (FP) results were calculated, and receiver operating characteristic curves were designed for numerical values.Results: Among single measurements and parameters, only the evaluation of scattergrams minimized FN and FP results (sensitivity 100%, specificity 94.8%, LR+ 19.17, and LR− 0.00), although their interpretation was subjective. The more objective approach based on the generation of a “leukemic flag” had a sensitivity of 100%, specificity of 87.0%, LR− of 0.00, and LR+ of 7.67.Conclusion: Using a novel gating strategy the Sysmex XT‐2000iV may be used effectively to screen canine blood for hematopoietic neoplasia.
Platelet Aggregation in Feline Cardiomyopathy
Authors: Helenski Cecelia A. , Ross James N. 
Published: March 2010

Platelet aggregation in response to adenosine diphosphate (ADP) was evaluated in 16 healthy cats and in 10 cats with cardiomyopathy. The minimum threshold concentration of ADP required to induce irreversible (2nd‐phase) aggregation was determined in each cat. The minimum ADP concentration needed for 2nd‐phase aggregation in platelets from healthy cats ranged from 1 μM to 100 μM ADP, with 56% (9/16) requiring 100 μM ADP. Of the remaining seven normal cats, three had platelets responding irreversibly to 10 μM ADP, and four had platelets responding to 1 μM ADP. In cats with cardiomyopathy, the threshold concentrations ranged from 0.01 μM ADP to 10 μM ADP. Two cats had platelets responding irreversibly to 0.01 μM ADP, whereas another cat had a threshold response at 0.1 nM ADP. Platelets from the remaining seven cats with cardiomyopathy exhibited 2nd‐phase aggregation in response to 1 μM ADP (five cats) or 10 μM ADP (two cats).Platelet counts ranged from 210,000/mm3to 630,000/mm3in healthy cats and from 218,000/mm3to 624,000/mm3in cats with cardiomyopathy. There was no apparent correlation between the platelet count and the magnitude of the threshold aggregation response, as measured by lag phase and slope of the aggregation curves.The results indicate that some cats with cardiomyopathy have platelets that are hyperaggregable to ADP in vitro.