bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of quantitative and qualitative research: an example using Critical Interpretive Synthesis
Authors: Flemming Kate 
Published: December 2009

flemming k. (2010) Synthesis of quantitative and qualitative research: an example using Critical Interpretive Synthesis. Journal of Advanced Nursing66(1), 201–217.AbstractTitle.  Synthesis of quantitative and qualitative research: an example using CriticalInterpretive Synthesis.Aim.  This paper is a report of a Critical Interpretive Synthesis to synthesize quantitative research, in the form of an effectiveness review and a guideline, with qualitative research to examine the use of morphine to treat cancer‐related pain.Background.  Critical Interpretive Synthesis is a new method of reviewing, developed from meta‐ethnography, which integrates systematic review methodology with a qualitative tradition of enquiry. It has not previously been used specifically to synthesize effectiveness and qualitative literature.Data sources.  An existing systematic review of quantitative research and a guideline examining the effectiveness of oral morphine to treat cancer pain were identified. Electronic searches of Medline, CINAHL, Embase, PsychINFO, Health Management Information Consortium database and the Social Science Citation Index to identify qualitative research were carried out in May 2008.Review methods.  Qualitative research papers reporting on the use of morphine to treat cancer pain were identified. The findings of the effectiveness research were used as a framework to guide the translation of findings from qualitative research using an integrative grid. A secondary translation of findings from the qualitative research, not specifically mapped to the effectiveness literature, was guided by the framework.Results.  Nineteen qualitative papers were synthesized with the quantitative effectiveness literature, producing 14 synthetic constructs. These were developed into four synthesizing arguments which drew on patients’, carers’ and healthcare professionals’ interpretations of the meaning and context of the use of morphine to treat cancer pain.Conclusion.  Critical Interpretive Synthesis can be adapted to synthesize reviews of quantitative research into effectiveness with qualitative research and fits into an existing typology of approaches to synthesizing qualitative and quantitative research.
How nurses seek and evaluate clinical guidelines on the Internet
Authors: Verhoeven Fenne , Steehouder Michaël F. , Hendrix Ron M.G. , van Gemert‐Pijnen Julia E.W.C. 
Published: December 2009

verhoeven f., steehouder m.f.,
Hendrix r.m.g. & van gemert‐pijnen j.e.w.c. (2010) How nurses seek and evaluate clinical guidelines on the Internet. Journal of Advanced Nursing66(1), 114–127.AbstractTitle.  How nurses seek and evaluate clinical guidelines on the Internet.Aim.  This paper is a report of a study conducted to assess nurses’ information‐seeking strategies and problems encountered when seeking clinical guidelines on the Internet, and to investigate the criteria they apply when evaluating the guidelines and the websites communicating the guidelines.Background.  As nurses are increasingly taking on clinical responsibilities, they should be able to use the Internet to access up‐to‐date clinical guidelines. Currently, nurses’ information‐seeking skills remain rather limited.Method.  In 2008, a convenience sample of 20 nurses solved scenario‐based tasks using the Internet to seek clinical guidelines regarding methicillin‐resistant Staphylococcus aureus while thinking aloud.Results.  General background information and universal precautions were successfully identified by participants, in contrast to more specific precautions. Nurses’ information‐seeking skills appeared rather basic, as they employed a limited number of search terms and consulted a limited number of websites. Ineffective searches were mainly caused by a mismatch between the guidelines and nurses’ tacit knowledge. Perceived practical relevance and information completeness were the most frequently applied quality criteria. Accuracy and disclosures, which are emphasized in existing e‐health literature, were considered less important. As long as information matched nurses’ practical and experiential wisdom, they were satisfied.Conclusion.  Nurses appeared to rely predominantly on tacit knowledge during the search process and while evaluating the retrieved guidelines. This is dangerous because nurses’ reliance on inaccurate information might result in inadequate behaviour. It is therefore essential to expand nurses’ current information base by tailoring both navigation structure and the guideline communication to dovetail with nurses’ tacit knowledge.
Chinese Breast Cancer Screening Beliefs Questionnaire: development and psychometric testing with Chinese‐Australian women
Authors: Kwok Cannas , Fethney Judith , White Kate 
Published: December 2009

kwok c., fethney j. & white k. (2010) Chinese Breast Cancer Screening Beliefs Questionnaire: development and psychometric testing with Chinese‐Australian women.Journal of Advanced Nursing66(1), 191–200.AbstractTitle. Chinese Breast Cancer Screening Beliefs Questionnaire: development andpsychometric testing with Chinese‐Australian women.Aim. This paper is a report of the development and psychometric testing of the Chinese Breast Cancer Screening Beliefs Questionnaire, a culturally sensitive questionnaire for measuring Chinese‐Australian women’s beliefs, knowledge and attitudes towards breast cancer and breast screening practices.Background. Breast cancer is the leading cause of cancer morbidity among Chinese‐Australian women. They are, however, 50% less likely to participate in all types of breast examination. A valid and reliable instrument to explore the breast cancer beliefs is essential for the development of interventions to promote breast cancer screening practices.Method. Items for the questionnaire were drawn from a literature review and in‐depth interviews. A panel of professional experts and lay women evaluated face and content validity. The instrument was translated from English to Chinese using back‐translation. In 2008, a total of 292 Chinese‐Australian women aged 22–78 years who were resident of Australia were included in testing the instrument. Multi‐trait analysis and Cronbach’s alpha were used to assess internal consistency reliability and exploratory factor analysis assessed construct validity.Results. The final 13‐item questionnaire had satisfactory validity and internal consistency. Cronbach’s alpha for the total scale was 0·76, and for the three subscales ranged from 0·70 to 0·79. Exploratory factor analysis showed that the scale reduced to three factors.Conclusion. Preliminary data suggest that the Chinese Breast Cancer Screening Beliefs Questionnaire is a valid, reliable and culturally sensitive instrument for the measurement of Chinese‐Australian women’s beliefs, knowledge and attitudes about breast cancer and breast cancer screening.
Building dynamic models and theories to advance the science of symptom management research
Authors: Brant Jeannine M. , Beck Susan , Miaskowski Christine 
Published: December 2009

brant j.m., beck s. & miaskowski c. (2010) Building dynamic models and theories to advance the science of symptom management research.Journal of Advanced Nursing66(1), 228–240.AbstractTitle. Building dynamic models and theories to advance the science of symptommanagement research.Aim. This paper is a description, comparison, and critique of two models and two theories used to guide symptom management research, and a proposal of directions for new theory or model development.Background. Symptom management research has undergone a paradigmatic shift to include symptom clusters, longitudinal studies that examine symptom trajectories, and the effects of interventions on patient outcomes. Models and theories are used to guide descriptive and intervention research. Over the past 15 years, four conceptual models or theories (i.e. Theory of Symptom Management, the Theory of Unpleasant Symptoms, the Symptoms Experience Model and the Symptoms Experience in Time Model) were used in a variety of symptom management studies.Data sources. Literature searches were performed in Medline and the Cumulative Index of Nursing and Allied Health Literature between 1990 and 2008 for models and theories that guide symptom management research. Related papers and book chapters were used as supporting documentation.Discussion. Comparison and critique of the models and theories revealed important gaps including lack of consideration of symptom clusters, failure to incorporate temporal aspects of the symptom experience and failure to incorporate the impact of interventions on patient outcomes.Conclusion. New models and theories should incorporate current trends in symptom management research, capture the dynamic nature of symptoms and incorporate concepts that will facilitate transdisciplinary research in symptom management. Researchers and clinicians need to build more expansive and dynamic symptom management models and theories that parallel advances in symptom research and practice.
Intimate male partner violence in the migration process: intersections of gender, race and class
Authors: Guruge Sepali , Khanlou Nazilla , Gastaldo Denise 
Published: December 2009

guruge s., khanlou n. & gastaldo d. (2010) Intimate male partner violence in the migration process: intersections of gender, race and class. Journal of Advanced Nursing66(1), 103–113.AbstractTitle.  Intimate male partner violence in the migration process: intersections ofgender, race and class.Aim.  This paper is a report of a s tudy of Sri Lankan Tamil Canadian immigrants’ perspectives on factors that contribute to intimate male partner violence in the postmigration context.Background.  Increasing evidence illustrates the extent and nature of intimate male partner violence and its links to a range of physical and mental health problems for women around the world. However, there has been little health sciences research on intimate male partner violence in the postmigration context in Canada.Methods.  Data were collected for this qualitative descriptive study in 2004 and 2005, through individual interviews with community leaders (n = 16), four focus groups with women and four with men from the general community (n = 41), and individual interviews with women who had experienced intimate male partner violence (n = 6). The research was informed by a postcolonial feminist perspective and an ecosystemic framework.Findings.  Participants’ conceptualization of the production of intimate male partner violence in the postmigration context involved (a) experiences of violence in the premigration context and during border crossing; (b) gender inequity in the marital institution; (c) changes in social networks and supports; and (d) changes in socioeconomic status and privilege.Conclusion.  Increasing immigration requires that nurses pay attention to and respond appropriately to women’s unique needs, based on complex and interrelated factors that produce intimate male partner violence in the postmigration context.
Simulation‐based learning in nurse education: systematic review
Authors: Cant Robyn P. , Cooper Simon J. 
Published: December 2009

cant r.p. & cooper s.j. (2010) Simulation‐based learning in nurse education: systematic review. Journal of Advanced Nursing66(1), 3–15.AbstractTitle.  Simulation‐based learning in nurse education: systematic review.Aim.  This paper is a report of a review of the quantitative evidence for medium to high fidelity simulation using manikins in nursing, in comparison to other educational strategies.Background.  Human simulation is an educational process that can replicate clinical practices in a safe environment. Although endorsed in nursing curricula, its effectiveness is largely unknown.Review methods.  A systematic review of quantitative studies published between 1999 and January 2009 was undertaken using the following databases: CINAHL Plus, ERIC, Embase, Medline, SCOPUS, ProQuest and ProQuest Dissertation and Theses Database. The primary search terms were ‘simulation’ and ‘human simulation’. Reference lists from relevant papers and the websites of relevant nursing organizations were also searched. The quality of the included studies was appraised using the Critical Appraisal Skills Programme criteria.Results. Twelve studies were included in the review. These used experimental or quasi‐experimental designs. All reported simulation as a valid teaching/learning strategy. Six of the studies showed additional gains in knowledge, critical thinking ability, satisfaction or confidence compared with a control group (range 7–11%). The validity and reliability of the studies varied due to differences in design and assessment methods.Conclusion. Medium and/or high fidelity simulation using manikins is an effective teaching and learning method when best practice guidelines are adhered to. Simulation may have some advantage over other teaching methods, depending on the context, topic and method. Further exploration is needed to determine the effect of team size on learning and to develop a universal method of outcome measurement.
The Effects of Family Firm Specific Sources of TMT Diversity: The Moderating Role of Information Exchange Frequency
Authors: Ling Yan , Kellermanns Franz W. 
Published: December 2009

abstractWe examine the relationships among three family firm specific sources of top management team (TMT) diversity (the generation in charge of the family firm, the number of family employees, and the number of employed generations) and family firm performance. By integrating upper‐echelons and team process research, we hypothesize that these TMT diversity sources interact with information exchange frequency among TMT members to affect family firm performance. Multisource survey data with lagged performance measurement, including CEOs and TMT members from 86 family firms, support our hypotheses. We discuss the implications of our findings and develop avenues for future research.
Expression quantitative trait loci analysis in plants
Authors: Druka Arnis , Potokina Elena , Luo Zewei , Jiang Ning , Chen Xinwei , Kearsey Mike , Waugh Robbie 
Published: December 2009

SummaryAn expression Quantitative Trait Locus or eQTL is a chromosomal region that accounts for a proportion of the variation in abundance of a mRNA transcript observed between individuals in a genetic mapping population. A single gene can have one or multiple eQTLs. Large scale mRNA profiling technologies advanced genome‐wide eQTL mapping in a diverse range of organisms allowing thousands of eQTLs to be detected in a single experiment. When combined with classical or trait QTLs, correlation analyses can directly suggest candidates for genes underlying these traits. Furthermore, eQTL mapping data enables genetic regulatory networks to be modelled and potentially provide a better understanding of the underlying phenotypic variation. The mRNA profiling data sets can also be used to infer the chromosomal positions of thousands of genes, an outcome that is particularly valuable for species with unsequenced genomes where the chromosomal location of the majority of genes remains unknown. In this review we focus on eQTL studies in plants, addressing conceptual and technical aspects that include experimental design, genetic polymorphism prediction and candidate gene identification.
Expression of pigeonpea hybrid‐proline‐rich protein encoding gene (CcHyPRP) in yeast and Arabidopsis affords multiple abiotic stress tolerance
Authors: Priyanka Bhyri , Sekhar Kambakam , Reddy Vudem Dashavantha , Rao Khareedu Venkateswara 
Published: December 2009

SummaryA hybrid‐proline‐rich protein encoding gene (CcHyPRP) has been isolated and characterized, for the first time, from the subtracted cDNA library of pigeonpea (Cajanus cajan L.) plants subjected to drought stress. Functionality of CcHyPRP has been validated for abiotic stress tolerance using the heterologous yeast and Arabidopsis systems. The CcHyPRP contained a repetitive proline‐rich (PR) N‐terminal domain and a conserved eight cysteine motif (8CM) at the C‐terminus. Southern analysis disclosed single‐copy nature of CcHyPRP gene in the pigeonpea genome. Northern analysis revealed higher levels of CcHyPRP transcripts in PEG, NaCl, heat (42°C), cold and ABA‐treated plants compared with the weak signals observed in the untreated plants, suggesting stress‐responsive nature of the CcHyPRP gene. In yeast, expression of CcHyPRP imparted marked tolerance against abiotic stresses exerted by PEG, high temperature, NaCl and LiCl. Transgenic Arabidopsis lines, expressing CcHyPRP under the control of CaMV35S and rd29A promoters, when subjected to PEG, mannitol, NaCl, LiCl and heat (42 °C) stress, developed into healthy plants with profuse root system and increased biomass in contrast to the weak‐stunted wild‐type plants. The CcHyPRP‐transgenics driven by stress‐inducible rd29A exhibited similar stress‐tolerance as that of CaMV35S‐lines without any negative effects on plant morphology, implying that stress‐inducible promoters are preferable for production of stress tolerant transgenics. The overall results amply demonstrate the profound effect of CcHyPRP in bestowing multiple abiotic stress tolerance at cellular and whole plant levels. Accordingly, the multipotent CcHyPRP seems promising as a prime candidate gene to fortify crop plants with abiotic stress tolerance.
Tax Reform, Delocation, and Heterogeneous Firms*
Authors: Baldwin Richard , Okubo Toshihiro 
Published: December 2009

AbstractThe standard international tax model is extended to allow for heterogeneous firms when agglomeration forces are important, enabling us to study the relocation effects of taxes that vary according to firm size. We show that allowing for heterogeneity permits a given tax scheme to have an endogenously different effect on the location decision of small and big firms, with the biggest firms being endogenously more likely to relocate in reaction to high taxes. We show that a reform that flattens the tax–firm–size profile can raise tax revenue without inducing any relocation.
Can Production Subsidies Explain China's Export Performance? Evidence from Firm‐level Data*
Authors: Girma Sourafel , Gong Yundan , Görg Holger , Yu Zhihong 
Published: December 2009

AbstractThis paper analyses the relationship between production subsidies and firms’ export performance using a very comprehensive and recent firm‐level database and controlling for the endogeneity of subsidies. It documents robust evidence that production subsidies stimulate export activity at the intensive margin, although this effect is conditional on firm characteristics. In particular, the positive relationship between subsidies and the intensive margin of exports is strongest among profit‐making firms, firms in capital‐intensive industries, and those located in non‐coastal regions. Compared to firm characteristics, the extent of heterogeneity across ownership structure (SOEs, collectives, and privately owned firms) proves to be relatively less important.
Firm Heterogeneity, Contract Enforcement, and the Industry Dynamics of Offshoring*
Authors: Naghavi Alireza , Ottaviano Gianmarco 
Published: December 2009

AbstractWe develop an endogenous growth model with R&D spillovers to study the long‐run consequences of offshoring with firm heterogeneity and incomplete contracts. In so doing, we model offshoring as the geographical fragmentation of a firm's production chain between a home upstream division and a foreign downstream division. While there is always a positive correlation between upstream bargaining weight and offshoring activities, there is an inverted U‐shaped relationship between these and growth. Whether offshoring with incomplete contracts also increases consumption depends on firm heterogeneity. As for welfare, whereas with complete contracts an R&D subsidy is enough to solve the inefficiency due to R&D spillovers, with incomplete contracts a production subsidy is also needed.
Foreign Direct Investment and the Incentives to Innovate and Imitate*
Authors: Brambilla Irene , Hale Galina , Long Cheryl 
Published: December 2009

AbstractWe propose a new channel of FDI spillovers on domestic firms, which operates through imitation of original products. Domestic heterogeneous firms may not introduce any new products, introduce a new product line (innovate), or develop a variety that is a close substitute to an existing product line (imitate). The presence of foreign firms generates incentives for imitation because they introduce original products that are vertically differentiated from domestic products. Using firm‐level panel data for China, we find that increased FDI presence in a given industry leads to more imitation, but not necessarily more innovation, by domestic firms.
Attitudes towards new HIV biomedical prevention technologies among a cohort of HIV‐negative gay men in Sydney, Australia
Authors: Poynten IM , Jin F , Prestage GP , Kaldor JM , Imrie J , Grulich AE 
Published: December 2009

ObjectivesThe aim of the study was to explore the awareness of rectal microbicides, the use of pre‐exposure prophylaxis (PREP) and the willingness to participate in biomedical HIV prevention trials in a cohort of HIV‐negative gay men.MethodsIn a community‐based cohort study, HIV‐negative homosexually active men in Sydney, Australia were questioned about awareness of rectal microbicides, use of PREP, and willingness to participate in trials of such products. Predictors of awareness and willingness to participate were analysed by logistic regression. Use of PREP was examined prospectively.ResultsOverall, 14% had heard of rectal microbicides. Older (P=0.05) and university‐educated men (P=0.001) were more likely to have knowledge of rectal microbicides. Almost one‐quarter (24%) of men reported that they were likely/very likely to participate in rectal microbicide trials. Among those men with definite opinions on participation, awareness of rectal microbicides was significantly associated with unwillingness to participate [odds ratio (OR) 0.78, 95% confidence interval (CI) 0.65–0.93, P=0.007]. Willingness to participate in trials using antiretroviral drugs (ARVs) to prevent HIV infection was reported by 43% of men, and was higher among those who reported unprotected anal intercourse (UAI) with HIV‐positive partners (OR 1.88, 95% CI 0.99–3.56). There was no evidence of current PREP use.ConclusionsThis study demonstrates that Australian gay men have had little experience with PREP use and rectal microbicides. About half would be willing to consider participation in trials using ARVs to prevent HIV infection. Extensive community education and consultation would be required before PREP or rectal microbicides could be trialled in populations of gay Australian men.