bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective assessment of the dismasking flap procedure as a craniofacial approach
Authors: Fujimoto Takuya , Imai Keisuke , Takahashi Makoto , Hatano Takaharu , Tamai Motoki , Nakano Tomoaki , Sakamoto Hiroaki , Ohata Kenji 
Published: April 2011

Object
In 1997 the authors presented the case of a 3-year-old girl who underwent complete resection of a huge tumor via a new technique using a dismasking flap. Since that report, 14 patients have undergone surgery using this technique. There have been few reports on long-term follow-up after a craniofacial surgical approach and reconstruction of a huge tissue defect. The authors report details of this procedure based on these cases, including long-term follow-up in the original case.

Methods
The dismasking flap is a cranioorbitofacial degloving method that uses a circumpalpebral approach with or without piriform margin incisions and presents a wide surgical field under direct vision. Fourteen patients have undergone surgery using the dismasking flap technique. These patients had multiple craniofacial bone fractures (3 cases) and malignant or premalignant craniofacial tumors (11 cases). Patients ranged in age from 3 to 62 years old. The longest follow-up period was 15 years. The results of these cases are reported regarding changes in the facial bones and soft tissues with growth, the various pathologies involved, and complications.

Results
Complications using this approach were lagophthalmos with ectropion of the lower eyelid, disturbance of the superior orbital nerve, disturbance of the inferior orbital nerve, maxillary hypoplasia, and blepharoptosis. In all affected patients these complications were almost always temporary. In 2 of the 14 cases, a repair operation for lagophthalmos was necessary, while others showed spontaneous improvement approximately 6 months to a year after the procedure. In the case with the longest follow-up duration, the patient's nose is asymmetrical, especially the alar portion, due to hypoplasia of the grafted bone and/or the fixation with titanium miniplates.

Conclusions
This flap is very useful for en bloc resection of huge skull base tumors, multiple craniofacial bone fractures, and as a lateral approach to a deep portion of the middle cranial base. Careful attention is necessary, however, because one may encounter unexpected complications if one does not ensure adequate protection of the perioperative flap. Meticulous postoperative management is also essential.
Evaluation of neoadjuvant therapy in patients with nongerminomatous malignant germ cell tumors
Authors: Nakamura Hideo , Makino Keishi , Kochi Masato , Ushio Yukitaka , Kuratsu Jun-ichi 
Published: April 2011

Object
The authors evaluated the effectiveness of a neoadjuvant therapy (NAT) consisting of combined chemoand radiotherapy followed by complete resection of the residual tumor in patients with nongerminomatous malignant germ cell tumors (NGMGCTs).

Methods
The authors treated 14 consecutive patients in whom NGMGCTs were diagnosed based on elevated levels of the tumor markers α-fetoprotein, human chorionic gonadotropin, and the β-subunit of human chorionic gonadotropin (β-HCG). Chemotherapy and radiotherapy were performed, and after the serum tumor markers level was in the normal or near-normal range, the residual tumors were completely resected.

Results
Residual tumors were confirmed in 11 of the 14 patients after NAT, and total removal was successful in 10 of the 11 patients. In the other patient the residual tumor could not be completely excised because it was attached to a deep vein. The follow-up duration ranged from 1.2 to 22.2 years. The 5-year event-free and total survival rates were 86% and 93%, respectively. Although 3 patients died, 2 of tumor recurrence and 1 of a radiation-induced secondary tumor (glioblastoma), the other 11 are alive and without evidence of tumor recurrence.

Conclusions
The authors consider their NAT protocol for NGMGCT to be highly effective in relation to survival for the patients with NGMGCT, but there are several quality of life issues that need to be resolved.
Detection of lasalocid residues in the tissues of broiler chickens by a new screening test total antibiotics
Authors: Kožárová Ivona , Šimková Jana , Mártonová Mária , Mačanga Ján , Levkut, ml. Martin 
Published: April 2011

The aim of the present study was to evaluate the microbial growth inhibition test Total antibiotics for the screening of lasalocid residues in the tissues of broiler chickens after its oral administration in medicated feed. The residues were investigated throughout the 5-day withdrawal period /WP/) and also on day 6 representing the first day following the WP. All broiler chicken tissues were positive for lasalocid. The breast muscle was positive (the presence of residues at/above the detection limit /LOD/ of method) up to day 1 of the WP, the thigh muscle, gizzard, heart, skin and fat up to day 3 of the WP and the liver and kidneys up to day 4 of the WP. When evaluating the dubious results (the presence of residues just below the LOD of method), the breast muscle was suspect positive up to day 3 of the WP and the gizzard, skin and fat up to day 4 of the WP. No positive or dubious results were detected on day 5 of the WP. The LOD of Bacillus stearothermophilus var. calidolactis for maduramycin was 500 µg.l-1.
Effect of sodium phosphates on selected food grade bacteria
Authors: Buňková Leona , Lorencová Eva , Jurčová Dora , Buňka František , Kráčmar Stanislav 
Published: April 2011

The aim of this study was to examine the inhibitory effect in vitro of selected sodium phosphates (under the corporate names Hexa 68, Hexa 70, Trikrystal, FST, Pyro 52, KPS, Didi) on selected gram-positive and gram-negative bacteria. Seven different concentrations of each phosphate were used. Sensitivity of the bacterial strains to phosphates was observed in broth supplemented with salts. In vitro was showed a negative effect of various phosphates on growth of selected gram-positive bacteria. Orthophosphates and diphosphates (pyrophosphates) did not have significant inhibitory effect on tested bacteria at neutral pH. With the exception of phosphate Trikrystal has not been found in vitro significant inhibitory effects on gram-negative bacteria.
An Introduction to Design and Analysis of Reliability Experiments
Authors: Rigdon Steven E. , Pan Rong , Montgomery Douglas C. , Taylor Dustin 
Published: May 2024

Abstract
Experiments for reliability usually involve lifetimes. Because lifetimes are usually not normally distributed, and because most life tests involve censoring, designing life tests for experiments is somewhat different from the usual normal‐theory designs. We present a review of regression models for life testing experiments, provide some examples, and discuss the optimal design of life tests.
Machine Learning Approaches for Statistical Process Control
Authors: Qiu Peihua 
Published: May 2024

Abstract
Machine learning approaches are widely used in different applications, including the ones involving statistical process control (SPC). In a traditional SPC problem (e.g., online monitoring of a production line), a small set of in‐control (IC) process observations is routinely collected before online process monitoring for estimating certain parameters of the IC process distribution. This dataset, however, does not contain any out‐of‐control (OC) process observations. Thus, supervised machine learning methods would be inappropriate to use in such cases since they require a training dataset that contains both IC and OC process observations. To overcome this difficulty, some machine learning methodologies specific for SPC have been developed based on one‐class classifications, artificial contrast, real‐time contrast, transparent sequential learning, and more. This article provides an overview on these methods.
Controlling Magneto‐Ionics by Defect Engineering Through Light Ion Implantation
Authors: Ma Zheng , Martins Sofia , Tan Zhengwei , Chen Song , Monteblanco Elmer , Liedke Maciej O. , Butterling Maik , Attallah Ahmed G. , Hirschmann Eric , Wagner Andreas , Quintana Alberto , Pellicer Eva , Ravelosona Dafiné , Sort Jordi , Menéndez Enric 
Published: May 2024

AbstractMagneto‐ionics relies on the voltage‐driven transport of ions to modify magnetic properties. As a diffusion‐controlled mechanism, defects play a central role in determining ion motion and, hence, magneto‐ionic response. Here, the potential of ion implantation is exploited to engineer depth‐resolved defect type and density with the aim to control the magneto‐ionic behavior of Co3O4 thin films. It is demonstrated that through a single implantation process of light ions (He+) at 5 keV, the magneto‐ionic response of a nanostructured 50 nm thick Co3O4 film, in terms of rate and amount of induced magnetization, at short‐, mid‐, and long‐term voltage actuation, can be controlled by varying the generated collisional damage through the ion fluence. These results constitute a proof‐of‐principle that paves the way to further use ion implantation (tuning the ion nature, energy, fluence, target temperature, or using multiple implantations) to enhance performance in magneto‐ionic systems, with implications in ionic‐based devices.
2D/0D Heterojunction Interface with Photovoltaic Enhancement and Stabilization for Label‐Free Exosome Biosensor
Authors: Wang Yindian , Zhong Suyun , Lee Jaebeom , Chen Hongxia 
Published: May 2024

AbstractThe selection and design of interface materials as the key to interface engineering is crucial for the excellent performance of optoelectronic devices, enabling multi‐functional integration at interfaces. MXene has been extensively employed in optoelectronic devices as an interface material. The primary drawback in interfacial applications, however, is MXene's vulnerability to oxidation in hot, humid environments, which severely reduces photovoltaic performance. Based on hetero‐interface engineering, this work offers a novel 2D‐semiconductor/0D‐plasma heterojunction MXene‐TA‐Au‐PEG (MTAP) as a high‐performance and multifunctional photovoltaic interfacial material. MTAP not only effectively protects MXene against stacking and spontaneous oxidation, but also exhibits excellent optoelectronic properties and interfacial antifouling capability. Moreover, MTAP is employed to enhance SPR spectroscopy, allowing for the direct, real‐time detection of tumor cell exosomes with LODs as low as 0.28 particles mL−1. MTAP effectively addresses the conventional “three S” requirements for sensors in terms of sensitivity, specificity, and stability by integrating photoelectric enhancement, interfacial antifouling, and oxidative stabilization characteristics. Finally, the results of serum sample analysis showed the sensor has some potential application value in clinical diagnosis. This study offers novel perspectives on the fabrication of 2D/0D heterojunctions using semiconductor and plasma materials, with the aim of developing improved sensing chips.
Ti Single Atom Enhancing Pt‐Based Intermetallics for Efficient and Durable Oxygen Reduction
Authors: Wang Zichen , Wu Wei , Jiang Haoran , Chen Suhao , Chen Runzhe , Zhu Yu , Xiao Yong , Lv Haifeng , Zhong Jun , Cheng Niancai 
Published: May 2024

AbstractThe insufficient durability of Pt‐based catalysts and the sluggish kinetics of oxygen reduction reaction (ORR) is hampering the development of proton exchange membrane fuel cells (PEMFCs) for commercialization. Herein, a single atom Ti‐modified activated nitrogen‐doped porous carbon (Ti‐a‐NPC) is designed to equalize O2‐activation/*OH‐removal through regulating the charge rearrangement of ultra‐small L12‐Pt3Co for efficient and durable oxygen reduction. The Ti single‐atom modified in the surface/pore of Ti‐a‐NPC can anchor the Pt‐based intermetallic nanoparticles (NPs) not only guarantees Pt‐based intermetallics’ ultra‐fine size (≈2.62 nm) but also maintains Pt‐based intermetallics during ORR process. The enhanced catalyst (L12‐Pt3Co/Ti‐a‐NPC) achieves 11‐fold mass activity (1.765 A mgPt−1) compared to commercial Pt/C. Notably, after 30 000 cycles of accelerated durability tests, the mass activity of the L12‐Pt3Co/Ti‐a‐NPC only decreased by 3.7%, while that of commercial Pt/C decreased by 37.1%. Rationalized by theoretical simulation, the introduction of Ti atoms can form charge channels between L12‐Pt3Co NPs and Ti‐a‐NPC, accelerating the charge transfer in the ORR process. Furthermore, the charge of L12‐Pt3Co will accumulate to Ti atoms and buffer the electron transfer of L12‐Pt3Co to the N atoms, thus optimizing the adsorption performance of the active site to the oxygen‐containing intermediate and improving the intrinsic activity of the catalyst.
Dextran‐Based Antibacterial Hydrogel Dressings for Accelerating Infected Wound Healing by Reducing Inflammation Levels
Authors: Liang Jianhao , Ling Junhong , Sun Deguan , Wu Guanhuai , Ouyang Xiao‐kun , Wang Nan , Yang Guocai 
Published: May 2024

AbstractInfected wounds pose challenges such as exudate management, bacterial infections, and persistent inflammation, making them a significant challenge for modern dressings. To address these issues in infected wounds more effectively, aerogel‐hydrogel biphase gels based on dextran are developed. The gel introduced in this study exhibits antibacterial and anti‐inflammatory properties in the process of wound therapy, contributing to accelerated wound healing. The aerogel phase exhibits exceptional water‐absorption capabilities, rapidly soaking up exudate from infected wound, thereby fostering a clean and hygienic wound healing microenvironment. Concurrently, the aerogel phase is enriched with hydrogen sulfide donors. Following water absorption and the formation of the hydrogel phase, it enables the sustained release of hydrogen sulfide around the wound sites. The experiments confirm that hydrogen sulfide, by promoting M2 macrophage differentiation and reducing the levels of inflammatory factors, effectively diminishes local inflammation levels at the wound site. Furthermore, the sodium copper chlorophyllin component within the hydrogel phase demonstrates effective antibacterial properties through photodynamic antimicrobial therapy, providing a viable solution to wound infection challenges.
Citric Acid: A Nexus Between Cellular Mechanisms and Biomaterial Innovations
Authors: Xu Hui , Yan Su , Gerhard Ethan , Xie Denghui , Liu Xiaodong , Zhang Bing , Shi Dongquan , Ameer Guillermo A. , Yang Jian 
Published: May 2024

AbstractCitrate‐based biodegradable polymers have emerged as a distinctive biomaterial platform with tremendous potential for diverse medical applications. By harnessing their versatile chemistry, these polymers exhibit a wide range of material and bioactive properties, enabling them to regulate cell metabolism and stem cell differentiation through energy metabolism, metabonegenesis, angiogenesis, and immunomodulation. Moreover, the recent US Food and Drug Administration (FDA) clearance of the biodegradable poly(octamethylene citrate) (POC)/hydroxyapatite‐based orthopedic fixation devices represents a translational research milestone for biomaterial science. POC joins a short list of biodegradable synthetic polymers that have ever been authorized by the FDA for use in humans. The clinical success of POC has sparked enthusiasm and accelerated the development of next‐generation citrate‐based biomaterials. This review presents a comprehensive, forward‐thinking discussion on the pivotal role of citrate chemistry and metabolism in various tissue regeneration and on the development of functional citrate‐based metabotissugenic biomaterials for regenerative engineering applications.
Synergistic Bulk and Surface Engineering for Expeditious and Durable Reversible Protonic Ceramic Electrochemical Cells Air Electrode
Authors: Chen Xi , Yu Na , Song Yufei , Liu Tong , Xu Hengyue , Guan Daqin , Li Zheng , Huang Wei‐Hsiang , Shao Zongping , Ciucci Francesco , Ni Meng 
Published: May 2024

AbstractReversible protonic ceramic electrochemical cells (R‐PCECs) offer the potential for high‐efficiency power generation and green hydrogen production at intermediate temperatures. However, the commercial viability of R‐PCECs is hampered by the sluggish kinetics of the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) within conventional air electrodes operating at reduced temperatures. To address this challenge, this work introduces a novel approach based on the simultaneous optimization of bulk‐phase metal‐oxygen bonds and in‐situ formation of a metal oxide nano‐catalyst surface modification. This strategy is designed to expedite the ORR/OER electrocatalytic activity of air electrodes exhibiting triple (O2−, H+, e−) conductivity. Specifically, this engineered air electrode nanocomposite‐Ba(Co0.4Fe0.4Zr0.1Y0.1)0.95Ni0.05F0.1O2.9‐δ demonstrates remarkable ORR/OER catalytic activity and exceptional durability in R‐PCECs. This is evidenced by significantly improved peak power density from 626 to 996 mW cm−2 and highly stable reversibility over a 100‐h cycling period. This research offers a rational design strategy to achieve high‐performance R‐PCEC air electrodes with superior operational activity and stability for efficient and sustainable energy conversion and storage.
Exciton Dissociation into Charge Carriers in Porphyrinic Metal‐Organic Frameworks for Light‐Assisted Li‐O2 Batteries
Authors: Wen Bo , Huang Yaohui , Jiang Zhuoliang , Wang Yuzhe , Hua Weibo , Indris Sylvio , Li Fujun 
Published: May 2024

AbstractLight‐assisted Li‐O2 batteries exhibit a high round‐trip efficiency attributable to the assistance of light‐generated electrons and holes in oxygen reduction and evolution reactions. Nonetheless, the excitonic effect arising from Coulomb interaction between electrons and holes impedes carrier separation, thus hindering efficient utilization of photo‐energy. Herein, porphyrinic metal‐organic frameworks with (Fe2Ni)O(COO)6 clusters are used as photocathodes to accelerate exciton dissociation into charge carriers for light‐assisted Li‐O2 batteries. The coupling of Ni 3d and Fe 3d orbitals boosts ligand‐to‐metal cluster charge transfer, and hence drives exciton dissociation and activates O2 for superoxide (•O2−) radicals, rather than singlet oxygen (1O2) under photoexcitation. These enable the light‐assisted Li‐O2 batteries with a low total overvoltage of 0.28 V and round‐trip efficiency of 92% under light irradiation of 100 mW cm−2. This work highlights the excitonic effect in photoelectrochemical processes and provides insights into photocathode design for light‐assisted Li‐O2 batteries.
Mechanochemically Robust LiCoO2with Ultrahigh Capacity and Prolonged Cyclability
Authors: Huang Weiyuan , Li Jianyuan , Zhao Qinghe , Li Shunning , Ge Mingyuan , Fang Jianjun , Chen Zhefeng , Yu Lei , Huang Xiaozhou , Zhao Wenguang , Huang Xiaojing , Ren Guoxi , Zhang Nian , He Lunhua , Wen Jianguo , Yang Wanli , Zhang Mingjian , Liu Tongchao , Amine Khalil , Pan Feng 
Published: May 2024

AbstractPushing intercalation‐type cathode materials to their theoretical capacity often suffers from fragile Li‐deficient frameworks and severe lattice strain, leading to mechanical failure issues within the crystal structure and fast capacity fading. This is particularly pronounced in layered oxide cathodes because the intrinsic nature of their structures is susceptible to structural degradation with excessive Li extraction, which remains unsolved yet despite attempts involving elemental doping and surface coating strategies. Herein, a mechanochemical strengthening strategy is developed through a gradient disordering structure to address these challenges and push the LiCoO2(LCO) layered cathode approaching the capacity limit (256 mAh g−1, up to 93% of Li utilization). This innovative approach also demonstrates exceptional cyclability and rate capability, as validated in practical Ah‐level pouch full cells, surpassing the current performance benchmarks. Comprehensive characterizations with multiscale X‐ray, electron diffraction, and imaging techniques unveil that the gradient disordering structure notably diminishes the anisotropic lattice strain and exhibits high fatigue resistance, even under extreme delithiation states and harsh operating voltages. Consequently, this designed LCO cathode impedes the growth and propagation of particle cracks, and mitigates irreversible phase transitions. This work sheds light on promising directions toward next‐generation high‐energy‐density battery materials through structural chemistry design.
Laser‐Induced Graphene Toward Flexible Energy Harvesting and Storage Electronics
Authors: Yang Jie , Yu Jiajie , Zhang Ke , Qiao Fen , Yu Gui 
Published: May 2024

AbstractEnergy harvesting and storage devices play an increasingly important role in the field of flexible electronics. Laser‐induced graphene (LIG) with hierarchical porosity, large specific surface area, high electrical conductivity, and mechanical flexibility is an ideal candidate for fabricating flexible energy devices which supply power for other electronic components. Through a simple laser irradiation process with designable routes, abundant precursors (or substrates) rapidly transform into patterned LIG without any other treatments. The structure and physicochemical properties of LIG can be regulated by controlling the processing strategies and parameters, enabling the optimization of device performance. The laser scribing method, as a non‐contact and in situ technique, proves to be efficient in integrating different LIG‐based devices, resulting in all‐in‐one flexible power platforms. Here, a systematic summary of recent advancements in LIG‐based flexible energy electronics is presented. The controllable synthesis of LIG, functional LIG, and 3D architectures are described by elucidating corresponding mechanisms and processing strategies. An overall review of flexible energy conversion and storage devices based on LIG is presented. Eventually, the challenges and opportunities of LIG‐based materials in flexible energy conversion and storage are briefly discussed.
Pencil‐Lead‐Based Quasi‐Equilibrium Glucose Biosensors
Authors: Shachneva Svetlana , Lielpetere Anna , Schuhmann Wolfgang 
Published: May 2024

AbstractForeign body response is the main reason for the limited lifetime of implantable glucose biosensors. A new measurement strategy exerting minimal disturbance from the equilibrium glucose concentration in the sensor compartment has been proposed to mitigate its adverse effects on the sensor signal. Here, a new measurement strategy using automatically fabricated and robust pencil‐lead‐based glucose biosensors is implemented. The sensor response depends on critical parameters such as redox‐polymer film thickness, film uniformity, rigidity, polymer composition, and the ratio between the enzyme and the polymer. These parameters are controlled by introducing a short‐chain redox polymer, a low crosslinker amount, a short‐chain electrografting agent and linker, pulse electrografting, and an automated fabrication procedure.