bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gene expression profiles of the incisor pulp tissue during fluorosis
Authors: Wu Y. , Hao Y.‐Q. , Li J.‐Y. , Zhou X.‐D. 
Published: May 2010

Wu Y, Hao Y‐Q, Li J‐Y, Zhou X‐D. Gene expression profiles of the incisor pulp tissue during fluorosis. International Endodontic Journal.AbstractAim  To examine gene expression levels within the cells of dental pulp tissue in fluorotic rats and normal subjects and to identify fluoride‐susceptible genes.Methodology  Female wistar rats were given 0.16 (control) or 100 parts per 106 fluoride ion in their drinking water. After 3 months, the teeth in the fluoride‐exposed animals showed signs of fluorosis. The animals were killed, and RNA was extracted from incisor pulp tissue and pooled into three fluorosis and three control pools. The females were analysed for gene expression profiles using microarray analysis and semi‐quantitative reverse transcriptase polymerase chain reaction (Sq‐RT‐PCR).Results  Of the 26 962 probe sets, duplicate hybridisation data indicated that 5443 genes were detected as being present by both targets. Two hundred and forty seven genes, that is 4.53% of detected genes, were 1.5‐fold or greater differentially expressed after fluoride treatment. Three interesting genes, dentine matrix protein 1, dentine sialophosphoprotein and Cadherin‐11, were confirmed as being down‐regulated by Sq‐RT‐PCR.Conclusions  The gene expression levels in rat pulp tissue changed during fluorosis. The gene expression profiles between the fluorotic model and the normal group will help to understand the multiple pathogenic mechanisms for the altered mineralization patterns observed in fluorotic dentine.
Fell‐Muir Lecture: Cartilage 2010 – The Known Unknowns
Authors: Hardingham Timothy E. 
Published: May 2010

SummaryOver the past 40 years there have been giant steps forward in our understanding of cellular and molecular biology that have given us the framework by which to understand tissue organization and tissue function on a range of scales. However, although the progress has been great, the more we have discovered, the more we are aware of what we don’t yet know. In this article, I would like to flag up some issues of cartilage biology, function and pathology where we still have significant ignorance. As scientists we all provide contributions to add to the greater understanding of science and progress is on a broad front, but gaps are left where particular difficulty is encountered and in life sciences it is no different. Progress is fast where new knowledge and techniques pave the way, but where study is complex and relevant techniques poorly developed the gaps are left behind. In cartilage research and matrix biology, the gaps can particularly be seen at interfaces between disciplines and where technology development has lagged behind and in the particular challenges of understanding how molecular properties can explain tissue macro properties.
Effects of low dose gamma irradiation on microbial inactivation and physicochemical properties of fried shrimp (Penaeus vannamei)
Authors: Wang He , Yang Ruijin , Liu Yanning , Zhang Weibin , Zhao Wei , Zhang Yanpeng , Hua Xiao 
Published: May 2010

SummaryChanges in microbiological, physicochemical and sensory properties of shrimp gamma irradiated with 60Co at doses of 0, 1, 3, 6, 9 kGy were investigated. Irradiation at 6 kGy eliminated most of the spoilage microorganisms and did not affect sensory quality. The L* value increased as irradiation dose increased, while a* value decreased as irradiation dose increased. Irradiation had no significant effect on the texture of shrimp samples; however, increasing the dose up to 9 kGy significantly increased the amount of volatile compounds, such as, alcohols, ketones, aldehydes, furans, and oxides. According to the total sensory points, the appearance and flavour of the shrimp product was considered as acceptable by sensory evaluation when irradiated at doses of 0–6 kGy. These results showed that gamma irradiation processing (<6 kGy) had the potential to extend the shelf life of fried shrimp.
Palynological and physicochemical data characterisation of honeys produced in the Entre‐Douro e Minho region of Portugal
Authors: Feás Xesús , Pires José , Estevinho María Letícia , Iglesias Antonio , De Araujo José Pedro Pinto 
Published: May 2010

SummaryHoney legislation has been addressed to establish the minimum marketing level of the product and the need for consumer protection through correct denominations. Research oriented toward assessment of floral origin and physicochemical properties may increase the commercial value of these products. The characteristics of thirty‐one honeys produced in the Entre‐Douro e Minho region in Portugal were studied. Pollen features and some physicochemical parameters (moisture, ash, pH, free acidity, electrical conductivity, hydroxymethylfurfural contain, apparent sucrose, reducing sugars and diastase activity) were determined. The samples were found to meet international honey specifications. The present study found a linear regression between the ash content of honeys and their specific conductivity. Five samples are listed as Eucalyptus honey, one sample as Citrus honey, and twenty‐five samples as multifloral honeys. Of the total, 87.1% exceeded the quality parameters and should be labelled as ‘virgin’ honey.
Quality assessment of dehydrated red bell pepper using tempering drying cycles
Authors: Carrillo Montes Juan Pablo , Cruz y Victoria María Teresa , Anaya Sosa Irasema , Santiago Pineda Teodoro 
Published: May 2010

SummaryQuality assessment of red bell pepper dices preserved through batch dehydration introducing tempering cycles were performed in this work. The parameters considered were: the percentages of ascorbic acid and final antioxidant activity retention, as well as the influence of calcium chloride on diffusivity and colour values. Although, a similar final moisture content was reached through different red bell pepper dehydration processes, but the one with tempering cycles had better qualities than those without tempering. Ascorbic acid and final antioxidant activity retention showed higher values and so were colour intensities compared to control samples in all cases. In respect to the effective diffusivity coefficients, there was an increment as the calcium chloride concentration increased. As of the treatments with tempering cycles, the best scheme was 15 min drying time and 30 min tempering time at 60 °C.
Main variables affecting the lactic acid fermentation of table olives
Authors: Medina Eduardo , Gori Chiara , Servili Maurizio , De Castro Antonio , Romero Concepción , Brenes Manuel 
Published: May 2010

SummaryAmong the olive varieties, Manzanilla is the most employed as table olives worldwide. Inoculation of the brines of Manzanilla and Gordal olives, which were not treated with alkali, with a strain of Lactobacillus pentosus was carried out and results indicated that variety is one of the main factors to be considered when fermenting olives, even more important than the salt level. This conclusion was based on the presence of a high concentration of antimicrobial compounds, namely the dialdehydic form of decarboxymethyl elenolic acid, either free or linked to hydroxytyrosol in the brines of the Manzanilla variety, as compared to the low level of these substances in the Gordal brines. Likewise, it was also observed that the inhibitory activity of Manzanilla olives against lactic acid bacteria could be counteracted by the addition of nitrogenous supplements such as MRS and yeast extract to their brines. Results obtained from this work are of great interest for the table olive industry in order to develop lactic acid fermentation in olives non‐treated with alkali.
Effect of muscle type and cooking temperature on liver‐like off‐flavour of five beef chuck muscles
Authors: Wadhwani Ranjeeta , Murdia Lalit K. , Cornforth Daren P. 
Published: May 2010

SummarySteaks (1.9 cm thick) from the US Department of Agriculture (USDA) Select grade beef chuck muscles (Infraspinatus, Longissimus dorsi, Serratus ventralis, Supraspinatus and Terres major) were cooked to two temperatures commonly applied in US restaurants (71 °C and 82 °C) and evaluated for liver‐like off‐flavour by trained panel. Pigment content of raw muscles were determined to establish its effect on liver‐like off‐flavour. Mean myoglobin content of Serratus (9.26 mg g−1) was significantly lower than other beef chuck muscles analysed in this study. Infraspinatus had highest (P < 0.05) mean liver flavour of 2.08 where other muscles had <2. Rancid flavour was slightly but significantly increased from 1.34 to 1.58 as internal cook temperature increased from 71 °C to 82 °C; however mean thiobarbituric acid (TBA) values were not affected by cooking temperature. Infraspinatus had small but significant incidence of liver‐like off‐flavour. Cooking temperature had a clear impact on rancidity as evaluated by trained panel but no direct impact on liver‐like off flavour was observed.
A pulsed electric field procedure for promoting Maillard reaction in an asparagine–glucose model system
Authors: Guan Yong‐Guang , Wang Jun , Yu Shu‐Juan , Zeng Xin‐An , Han Zhong , Liu Yan‐Yan 
Published: May 2010

SummaryEffects of pulsed electric field (PEF) on pH, intermediate products, asparagine and glucose content, browning value, reducing power as well as antioxidant activity of an asparagine–glucose solution were explored in this paper. Results showed that the solution’s UV–Vis absorbance at 294 nm and 420 nm was significantly increased from 0 to approximately 1.14 and 0.74, respectively, at PEF intensity of 40 kV cm−1 for 7.35 ms treatment. The temperature of PEF treated samples were overall lower than 40 °C. It was also detected that the antioxidant activity of treated sample was correspondingly increased by 20.33%. Meanwhile, 14% reduction of asparagine content and 66% reduction of glucose content were observed. It was demonstrated from high performance liquid chromatography analysis that Maillard reaction in the model system had been enhanced by PEF treatment as no 5‐hydroxymethyl‐2‐furaldehyde was generated. This study indicates that pulsed electric field treatment, especially with higher intensities, is a means to significantly promote the Maillard reaction in an asparagine–glucose solution.
A new deletion mutation of fragrant gene and the development of three molecular markers for fragrance in rice
Authors: Shao G. N. , Tang A. , Tang S. Q. , Luo J. , Jiao G. A. , Wu J. L. , Hu P. S. 
Published: May 2010

With 3 figures and 3 tables AbstractFragrance is an important quality trait of rice, which is mainly controlled by loss‐function of the betaine aldehyde dehydrogenase gene (badh2) on rice chromosome 8. Two deletion mutations of Badh2 have been reported to associate with fragrance in rice. Allelic test showed that the fragrant gene of ‘Zaimiaoxiangnuo’ is allelic to badh2‐E7 (8 bp deletion in exon 7 of Badh2). Sequencing and BLAST analysis showed that the allele in ‘Zaimiaoxiangnuo’ is a new mutation, i.e. deletion of 803 bp between exons 4 and 5. A marker FMbadh2‐E4‐5 was developed for the detection of the new deletion site of fragrant gene. FMbadh2‐E4‐5 and the two previously reported functional markers were used to genotype the fragrant genes of four non‐fragrant and 22 fragrant rice varieties. The deletions were absent in all non‐fragrant rice varieties, but present in all fragrant rice varieties. Eight fragrant rice varieties were positive for the FMbadh2‐E4‐5 marker. These findings are useful in the breeding of fragrant rice varieties.
Are Australian rural women aware of coronary heart disease?
Authors: Crouch Rosanne , Wilson Anne 
Published: May 2010

Crouch R, Wilson A. International Journal of Nursing Practice 2010; 16: 295–300 Are Australian rural women aware of coronary heart disease?Heart disease is the leading cause of morbidity and mortality in Australian women. In 2005, 109 000 women died of heart disease and 27 000 women died of breast cancer. The reported study sought to assess rural women's level of awareness of heart disease as the leading cause of death. A self‐enumerated questionnaire designed to collect information on rural women's perception and awareness of heart disease was distributed to women attending a women's health clinic in a regional hospital. Of 65 participants, 13% (n = 8) identified heart disease as the most significant health problem. Sixty‐four per cent of women participating in the study reported that breast cancer claims more lives than heart disease. The authors concluded that women do not perceive heart disease as a substantial health concern. Programmes directed at young women to improve their perception of risk for heart disease and to encourage them to make healthy lifestyle choices are required to reduce overall heart disease morbidity and mortality.
Viral bronchiolitis for the clinician
Authors: Fitzgerald Dominic A 
Published: May 2010

AbstractViral bronchiolitis is common, and about 98–99% of infants are managed in the home. Because about 95% of infants <2 years old are infected with respiratory syncytial virus, however, bronchiolitis is the commonest reason for admission to hospital in the first 6 months of life. It is usually a self‐limiting condition lasting around a week in previously well children. About 1% of infants are admitted to hospital, and about 10% of hospitalised infants will require admission to the intensive care unit. Respiratory syncytial virus is isolated from about 70% of infants hospitalised with bronchiolitis. The emphasis of hospital treatment is to ensure adequate hydration and oxygenation. Other than supplemental oxygen, little in the way of pharmacological treatment has been demonstrated to alter the course of the illness or the risk of wheezing in the months following bronchiolitis.
Adolescents seeking weight management: Who is putting their hand up and what are they looking for?
Authors: Truby Helen , Baxter Kim , Elliott Sarah , Warren Janet , Davies Peter , Batch Jennifer 
Published: May 2010

AbstractWe describe the characteristics of adolescents seeking treatment for obesity via the ‘Eat Smart’ feasibility study; an intensive 12 week dietitian‐led weight management programme with an emphasis on lifestyle change. It was designed to test the feasibility of a structured low‐fat diet compared with a semi‐structured reduced carbohydrate plan compared with a model of ‘standard care’– an unstructured low fat approach. When compared with non‐participants, participants were predominantly female and lived in lower socioeconomic areas. When given the choice of dietary approach, 50% elected reduced dietary carbohydrate, 43% structured low fat and 7% chose ‘standard care’. Modest weight loss was achieved over 12 weeks, with both the structured low fat and reduced carbohydrate formats. Families showed a strong preference for structured eating plans, in particular seeking assistance with correct portion size. The current standard model of unstructured advice was both unpopular and relatively unsuccessful.
Superior vena cava obstruction: Dangers of a missed diagnosis
Authors: Holme Harriet , Nanduri Vasanta 
Published: May 2010

AbstractWe report the case of a 7 year old girl who presented to the Children's Emergency Department with a 6 week history of bilateral facial and neck swelling. She had felt generally unwell, tired, with a recent onset of dry cough, and had presented multiple times to her general practitioner (GP) who after initially unsuccessfully trying an antihistamine, had given her five courses of soluble Betamethasone (corticosteroid) over six weeks, for presumed allergy; this temporarily relieved her symptoms for a couple of days each time. On subsequent referral to Accident and Emergency she was found to have a superior mediastinal mass, with a left pleural effusion and mediastinal deviation to the right. Further investigation confirmed the diagnosis of a T‐cell lymphoma causing superior vena cava obstruction of blood flow through the SVC to the right atrium and is a classical oncological emergency. This case report highlights the importance of recognizing superior vena cava obstruction and the need for awareness of malignancy as a differential diagnosis when initially presented with a child with non‐specific respiratory findings. We highlight that acute tumour lysis syndrome, a life threatening metabolic emergency that results from massive cytolysis of malignant cells, may occur after a single dose of corticosteroids and one should be aware of this potentially life‐threatening complication.
Hyperperfusion in primary somatosensory region related to somatic hallucination in the elderly
Authors: Nemoto Kiyotaka , Mizukami Katsuyoshi , Hori Takafumi , Tachikawa Hirokazu , Ota Miho , Takeda Tohoru , Ohnishi Takashi , Matsuda Hiroshi , Asada Takashi 
Published: May 2010

Aim:  The purpose of the present study was to investigate the regional cerebral blood flow (rCBF) of patients with delusional disorder, somatic type (DDST) exhibiting somatic hallucination.Methods:  Five patients diagnosed with DDST, as well as 20 control subjects, were examined. All subjects underwent technetium‐99m ethyl cysteinate dimer brain perfusion single‐photon emission computed tomography. Statistical analysis was performed with SPM5, using a two‐sample t‐test model to test the regional population effect on rCBF.Results:  Patients with DDST had a significant increase in perfusion in the left post‐central gyrus and the right paracentral lobule, both of which are involved in somatic sensory processing.Conclusion:  Somatic hallucination might be associated with increased perfusion in the primary somatosensory regions.
Synchronous radiation‐induced orbital meningioma and multiple cavernomas
Authors: Paramanathan Nirosha , Ooi Kenneth Gek‐Jin , Reeves Dianne , Wilcsek Geoff A 
Published: May 2010

AbstractSynchronous radiation‐induced tumours are extremely rare. We present the first reported case of synchronous radiation‐induced orbital meningioma and cavernomas of the cerebellum and bilateral basal ganglia, presenting 16 years after ionizing radiation therapy for parietal anaplastic ependymoma, at the age of five. This case again underscores the risks of radiotherapy to children.
The Usefulness of Screaning for Chlamydial Trachomatis Infection with Cervical Mucus Leukocyte Esterase
Authors: El‐Shourbagy Mahmoud , Diab Khaled M. , Abdalla Mahmoud Y. , El‐Salam Magda Abd , Mohasb Shadia H. 
Published: May 2010

AbstractObjective: To evaluate the ability of leukocyte esterase dipstick test (LET) performed in cervical mucus to predict direct immunofluorescent (DIF)‐verified Chlamydia trachomatis (Ct) cervical infection.Method: Eighty women with inflammatory cervico‐vaginal smear were submitted to both an endocervical smear, to verify Ct cervicitis by DIF technique; and a cervical mucus sample to perform LET. Results of LET and DIF were matched.Results: Among 30 Chlamydial positive subjects, cervical mucus esterase test was positive in 28 (93.3%); while among 50 Chlamydial negative controls, esterase test was negative in 43 subject (86%). The sensitivity, specificity, positive and negative predictive values for LET were 93.3%, 86%, 80% and 95% respectively.Conclusion: Cervical mucus LET is a simple, cost effective screening test, with promising accuracy, for Ct cervical infection among women with inflammatory cervico‐vaginal smears.
Early Invasive Adenocarcinoma of the Fallopian Tube: A Case Report and Review of the Literature
Authors: Kurisu Miho , Konishi Ikuo , Mandai Masaki , Kuroda Hideki , Tsuruta Yuko , Yura Yasuichiro , Nanbu Kanako , Hamid Atia A. 
Published: May 2010

AbstractWe present an early invasive adenocarcinoma of the fallopian tube, which was incidentally found in a 45‐year‐old woman undergoing a laparotomy for uterine myoma. Histological examination of the hydropic tubes revealed widespread endosalpingeal hyperplasia without atypia in both tubes. In addition, the left tube contained 3 scattered lesions of carcinoma in situ, one of which was accompanied by a microfocus of definite stromal invasion confined within the endosalpingeal mucosa. Such a case seems extremely rare, and it might represent the histological appearance of an early invasive feature of tubal carcinoma. We reviewed previously reported cases of in situ and/or early invasive carcinomas of the fallopian tube with respect to the pathological diagnosis and histogenesis of primary tubal adenocarcinomas.
Primary Term Ovarian Pregnancy Superimposed by Intrauterine Pregnancy: A Case Report
Authors: Shahabuddin A. K. M. , Chowdhury Sameena 
Published: May 2010

AbstractA case of primary ovarian pregnancy proceeding upto term superimposed by another intrauterine pregnancy is presented. Compound extrauterine and intrauterine pregnancy is a rare obstetric phenomenon and still rarer is a primary ovarian pregnancy proceeding upto the term. The condition was diagnosed at laparotomy during the second trimester of current pregnancy. Diagnostic laparotomy was done because the ovarian pregnancy was mimicking an ovarian tumur. The ovarian pregnancy was successfully managed by surgery. Normal vaginal delivery of a term intrauterine pregnancy occurred in due time. The difficulty of diagnosing the heterotopic pregnancy is discussed and the clinico‐pathological eatures of primary term ovarian pregnancy is emphasized, as it is a very rare condition.
Intrauterine Therapy of Fetal Atrial Flutter
Authors: Uerpairojkit B. , Tanawattanacharoen S. , Manotaya S. , Wisawasukmongchol W. , Chottivittayatarakorn P. , Charoenvidhya D. 
Published: May 2010

AbstractAn increased awareness of fetal arrhythmias by obstetricians has resulted in a growing number of diagnosed cases of fetal cardiac problems. A fetus with atrial flutter diagnosed at 31 weeks of gestation was successfully converted to normal sinus rhythm in utero by maternal administration with digitalis. The fetal heart rate stayed in a normarhythm with a maintenance dose of 0.5 mg/day. The fetus was delivered spontaneously at term and the neonatal heart rate has been in normal rhythm without any medical treatment.
Abruptio Placentae: Risk Factors and Perinatal Outcome
Authors: Abu‐Heija Adel , Al‐Chalabi Haifa , El‐lloubani Nahar 
Published: May 2010

AbstractObjective: It is a case control study, conducted in order to determine the risk factors, and to find out the perinatal outcome of abruptio placentae in women delivered at the Princess Badeea Teaching Hospital in North Jordan.Methods:We reviewed all cases of placental abruption delivered between 15th April 1994 till 26 November 1995 and to compare that with pregnancies and deliveries not complicated by abruptio placentae.Results:During the study period there were 108 cases of abruptio placentae and 108 cases of the control group. The total number of women delivered were 18,256, so the incidence of abruptio placentae was 5.9 per 1000 births. When compared to the control group, abruptio placentae occurred more in parous women (para ≥ 5) (p < 0.0005), more preterm deliveries (p < 0.0001) with more birth weight < 2,500 g (p < 0.0001). Preeclampsia and pregnancy induced hypertension, intrauterine growth retardation, caesarean delivery, and intrauterine fetal death occurred more in patients with abruptio placentae.Conclusion:High parity, preeclampsia and hypertension are significant etio‐logical determinants of abruptio placentae.