bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Staining and External Bleaching on the color stability and Surface Roughness of Universal-Shade Resin- Based Composite
Authors: AlHabdan AlHanouf , Alsuhaibani Amal , Alomran Lama , Almutib Lulwah 
Published: May 2024

Abstract

Aim: This study evaluated the color stability and surface roughness of four universal-shade resin-based composites after staining and external bleaching with 40% hydrogen peroxide.
Methods: Two universal shade resin-based composites and two nanohybrid composites were tested. Twenty disc-shaped specimens from each material were fabricated and divided into two subgroups: one group was stained and bleached (staining group) and the other received bleaching treatment only (control group). The staining group was stained with coffee solution for 24 h. Subsequently, each sample of all four materials was bleached using an in-office bleaching gel using 40% hydrogen peroxide. Color measurements were performed using a spectrophotometer to obtain the International Commission on Illumination parameters, L*; a*; and b*, for each of the following periods: baseline, after bleaching, and two weeks after bleaching for the control group. The staining group was examined at baseline, after staining, after bleaching, and two weeks after bleaching. Surface roughness (Ra) of all the materials after each treatment step were also recorded.
Results: Descriptive statistics (means and standard deviations) were used to describe color measurements and surface-roughness values. Two-analysis of variance and one-way analysis of variance were used to compare the mean values of surface roughness, L*, a*, b*, and ΔE values.
Statistically significant differences and clinically acceptable ΔE were observed between all materials during the different stages in color measurements, whereas the surface roughness were significantly different for each study material and treatment mode.
Conclusion: Staining with coffee solution and in-office bleaching produced acceptable color changes. Increased surface roughness values were observed after staining and bleaching the tested resin-based composites.
Higher serum fibroblast growth factor 2 levels are prone to appear in younger patients with Takayasu's arteritis
Authors: gao na , li taotao , cui wei , zhao limin , pan lili 
Published: May 2024

Abstract

Objectives
Takayasu's arteritis (TAK) is a rare large vessel vasculitis. The fibroblast growth factor 2(FGF2) has angiogenic property. This study aims to investigate expression of FGF2 in TAK patients.
Methods
Serum cytokines of 48 patients with TAK and 32 healthy controls were detected using cytokine cytometric bead array. The percentage of T cell subsets of TAK patients were analyzed by flow cytometry analysis. Immunohistochemical staining analysis were used to detect FGF expression in the aortic wall of 3 TAK patients and 3 atherosclerosis patients.
Results
Serum level of FGF2 were significantly elevated in patients with TAK compared to controls [40.22 (29.88, 60.01) pg/ml vs. 26.51(21.28, 30.08) pg/ml, p < 0.001].Serum FGF2 level was negatively correlated to age (r = -0.313, p = 0.030),age of TAK onset(r=-0.329, p = 0.023) and positively correlated to cytokines [G-CSF (r = 0.361, p = 0.002), CCL2(r = 0.251, p = 0.034), CCL3(r = 0.572, p < 0.001), IL-4(r = 0.421, p < 0.001), IL-8(r = 0.646, p < 0.001), IL-17(r = 0.812, p < 0.001)Furthermore, we found marked expression of FGF2 was shown in aortic lesions of patients with TAK compared with those of atherosclerosis(5.380% ± 0.986% vs. 0.019% ± 0.012%, P = 0.011).
Conclusions
Higher serum FGF2 levels are prone to appear in younger TAK patients with Takayasu's arteritis. FGF2 might be involved in the pathogenesis in TAK.
Enhancing Stoma Care Quality: Implementing a PDSA Cycle-Based Program for Colorectal Cancer Patients
Authors: Zhu Yingjiao , Yao Na , Tang Lijun , Yang Chunbaixue , Lin Xingyu , Lin Xiaoyan 
Published: May 2024

Abstract

Background: Effective quality management is of prime importance in reducing the risk of ostomy’s complications. It is necessary to improve the quality of stoma practice specialist and increase patients' awareness of self-care and the need to temporarily withhold certain medication.
Objectives: A quality stoma practice specific program (QSPSP) was introduced to address these concerns and enhance the care among patients who had received a diagnosis of colorectal cancer (CRC) and underwent surgery with stoma creation at a single medical center. PDSA model was approached for care service improvement in three cycles (the Plan, Do, Study, Act/cycle) to test and generate new ideas relating to patients' needs.
Measurements and Results: The QSPSP was identified through the application of the PDSA model. Viable strategies to address these challenges within the QSPSP program encompass: (1) Recruitment of a certified stoma-specific nurse. (2) Creation of standardized guidelines. (3) Integration of an interdisciplinary team. (4) Enhancement of patient self-care education. (5) Identification of specific goals. (6) Provision of feedback on intervention and evaluation by comparison of QLQ-C30 scores
Conclusion: The quality stoma practice specific program has achieved qualification, and its initiatives have been effectively disseminated to enhance professional awareness of the paramount importance of quality in patient care.
FBG seismometer optimized by genetic algorithm to realize 3-axis vibration detection using one fiber without bending
Authors: Guo Teng , Song Hao , Sha Sha , Li Cunxia , Xu Ming 
Published: May 2024

Abstract

We propose a 3-axis FBG seismometer in which the X- and Y-axis hinge structures are optimized and designed by genetic algorithm to precisely modulate their sensitivity and resonant frequency, thence possess basically the same vibration characteristics with the pre-fabricated spring structure that responsible for Z-axis vibration detection. Sensors on three axes operate in a frequency band of 20-90 Hz, the sensitivities of the proposed accelerometer in X,Y and Z directions are 401.088 pm/g, 413.580 pm/g and 402.075 pm/g respectively. Such application of algorithm enables our seismometer to realize quasi-distributed 3-dimensional vibration detection using one single fiber without bending, which will significantly reduce the diameter of the seismometer, eliminate the bending loss and broaden its application scenario.
Effect of tracheal intubation performed by trauma surgeons on patients with severe traumatic brain injury
Authors: Wang Liang , Sun Zhengjie , Xu Feng , Sharifi Nona Hashem , Zhang Pengjie , Ling Weihua , Chen Xionghui 
Published: May 2024

Abstract

Background: An early intubation is predominantly performed by anesthesiologists for patients experiencing severe traumatic brain injury (STBI). Currently, a growing number of trauma surgeons in China have acquired proficient skills in tracheal intubation through rigorous training offered at trauma centers. In this article, we performed a retrospective observational cohort investigation with the aim of comparing the outcomes of endotracheal intubation conducted by trauma surgeons and anesthesiologists in the emergency room, specifically focusing on patients suffering from STBI.
Methods: Data were gathered from all STBI patients who received intubation between January 2018 and March 2023. There are two study groups based on the intubation performers: the trauma surgeon's intubation (TI) group and the anesthesiologist's intubation (AI) group. The age, sex, Injury Severity Score (ISS), Glasgow Coma Scale (GCS), admission SpO2, PO2, PCO2, SBP, RR, HR, injury mechanism, intracranial lesion type, duration of endotracheal intubation, 1-min success rate of intubation, complications related to intubation, time from admission to intubation, duration of mechanical ventilation, incidence of aspiration pneumonia, 3-day mortality rate and the 30-day mortality rate were recorded.
Results: Among the 356 patients with STBI, 219 individuals fulfilled the inclusion criteria (comprising of 142 patients in the TI group and 77 patients in the AI group). No notable statistical differences were observed between the two groups in terms of age, sex, ISS, GCS, admission SpO2, PO2, PCO2, SBP, RR, HR, injury mechanism, and intracranial lesion type. The AI group exhibited a considerably shorter time from admission to intubation (p<0.01). Furthermore, the AI group demonstrated a reduced incidence of aspiration pneumonia as well as a decreased duration of mechanical ventilation (p<0.05).
Conclusion: The intubation of patients with STBI by trauma surgeons early can reduce aspiration pneumonia incidents and duration of mechanical ventilation.
A clustering-based survival comparison procedure designed to study the Caenorhabditis elegans Model
Authors: Grollemund Paul-Marie , Poupet Cyril , Comte Elise , Bonnet Muriel , Veisseire Philippe , Bornes Stéphanie 
Published: May 2024

Abstract

Caenorhabditis elegans holds significant importance in current research, serving as a pivotal model organism that has greatly advanced the understanding of fundamental biological processes such as development, cellular biology, and neurobiology, helping to promote major advances in various fields of science. In this context, the survival of the nematode under various conditions is commonly investigated, employing a statistical survival analysis typically based on hypothesis testing, providing valuable insights into the factors influencing its longevity and its response to varying environmental factors. The extensive reliance on hypothesis testing is acknowledged as a concern in the scientific analysis process, emphasizing the need for a comprehensive evaluation of alternative statistical approaches to ensure rigorous and unbiased interpretation of research findings. In this paper, we propose an alternative method to hypothesis testing for evaluating differences in nematode survival. Our approach relies on a clustering technique that takes into account the complete structure of survival curves, enabling a more comprehensive assessment of survival dynamics. The proposed methodology helps to identify complex effects on nematode survival and enables us to derive the probability that a treatment induces a specific effect. To highlight the application and benefits of the proposed methodology, it is applied to two different datasets, one simple and one more complex.
Comparative Analysis of Cysteine Protease-based Nano- formulations to Manage Callosobruchus maculatus Fabricius and Trogoderma granarium Everts in Stored Products
Authors: Ahmad Sarah , Akrem Ahmed , Najam-ul-Haq Muhammad , Mehmood Sohaib , Batool Muazzama , Saeed Ahsan , Jabeen Fahmida , Ashraf Saima , Bashir Nabila , saeed Qamar 
Published: May 2024

Abstract

Insect pests cause one-third of grain loss during storage. This should be minimized through sustainable management to assure food security. This study describes development of nano-formulated biopesticides for managing stored product insect pests Callosobruchus maculatus (Fabricius) (Chrysomelidae; Coleoptera) and Trogoderma granarium (Everts) (Dermestidae; Coleoptera). Cysteine protease (PeuCP) from Populus euphratica was extracted, purified (by ammonium sulfate saturation prior to gel filtration chromatography), and identified through LC-MS/MS. The molecular interaction of PeuCP with substrate (chitin) was documented via in-silico study. The PeuCP was formulated with Graphene Quantum Dots (GQDs) and Zinc Oxide Nanoparticles (ZnO NPs). The insecticidal activity of PeuCP was assessed by bioassays against two stored product insect pests at three concentrations (10, 5 and 2.5 mg/g). Computational analysis showed molecular interaction of PeuCP at five potential sites for ligand (N-acetyl-D-glucosamine) binding in which the strongest site with the highest drug score (Site-1) was located near N-terminus. The insecticidal assays of PeuCP without nano-formulation revealed inhibited population buildup of C. maculatus and delayed life stages development in T. granarium. The growth inhibition of tested insects confirmed the substrate binding of PeuCP. The results also revealed increased insecticidal activity of PeuCP after nanoformulations, among which GQDs nanoformulation was more promising. Nanoformulated PeuCP had the potential to control stored grain insect pests as alternative to chemical insecticides.
Eating Behaviors, Physical Activity and Weight Loss after Motivational Interviewing in Patients who have Undergone Laparoscopic Sleeve Gastrectomy
Authors: Sobhani Zahra , Poursharifi Hamid , Khazraei Hajar , Hosseini Seyed Vahid 
Published: May 2024

Abstract

Background: There is strong evidence that obesity, especially morbid obesity, is associated with serious and dangerous physical illnesses, and that weight loss in these patients can improve their social functioning, quality of life, and mental health.
Objectives: The goal of this study was to evaluate eating behaviors, physical activity, and weight loss after motivational interviewing (MI) in patients who have undergone laparoscopic sleeve gastrectomy (LSG).
Setting: Mother and Child Hospital in Shiraz during spring and summer of 2019.
Methods: The thirty obese patients (Body Mass Index:BMI ≥ 35) who had undergone LSG were selected and randomly divided into two groups of control and experimental. Data were collected using bariatric surgery self-management behaviors questionnaire. MI was conducted for the experimental group during four weeks.
Results: The results indicated that MI caused a significant difference between the two groups in at least one of the dependent variables (eating behaviors, supplement consumption and physical activity). Therefore, MI is effective and appropriate in obese patients who had undergone LSG towards achieving optimal weight loss.
Conclusion: Changing the lifestyle in patients that have undergone bariatric surgery is achieved by meeting the psychological needs, namely autonomy, competence, and communication with others.
Improving curcumin bioavailability via sustained release of curcumin and piperine co-encapsulated in electro-sprayed multilayer chitosan microparticles
Authors: Cao-Luu Ngoc-Hanh , Luong Huynh-Vu-Thanh , Pham Duy Toan , Nguyen-Thi Bich-Thuyen , Ngo-Truong Ngoc-Mai , Dang Huynh-Giao , Nguyen Tuong-Vy 
Published: May 2024

Abstract

Curcumin (CCM) is a natural compound with strong tumor-inhibiting activity. However, CCM is not widely used for cancer treatment because of its poor water solubility, penetration, and bioavailability. In this study, CCM and piperine (PPR), a bio-enhancer, were co-encapsulated within chitosan (CS) by co-axial electro-spraying method aiming to increase CCM bioavailability. Two formulation approaches have been proposed, including (1) co-encapsulation of CCM and PPR in micro-particle core (e.g., CCM/PPR@CS) and (2) separate encapsulation of CCM and PPR in two different CS layers (e.g., CCM@PPR@CS). The optimal electro-spraying parameters were investigated and found to be applied voltage of 15 kV, flow-rate of 0.1/0.2 mL h− 1 (core/shell), and needle tip-to-collector distance of 10 cm for CCM/PPR@CS micro-particle; and applied voltage of 19 kV, flow rate of 0.1/0.2/0.3 mL h− 1 (inner-layer/middle-layer/outer-layer), and working distance of 14 cm for CCM@PPR@CS formulation. The obtained particles were non-agglomerated, spherical, and possessed core-shell structure with clear boundaries, relatively wide distribution with mean diameters of 366 ± 136 nm for CCM/PPR@CS and 784 ± 139 nm for CCM@PPR@CS. As expected, the in vitro data showed that PPR was released faster than CCM with the separation of PPR and CCM in two different layers, and the drugs were released more strongly at pH 5.5 than at pH 7.4 due to pH sensitivity of chitosan shell. The CCM and PPR cumulative releases were also high (70–80%). In conclusion, the CCM@PPR@CS structure could be utilized as a potential drug delivery system for decreasing denaturation and enhancing the absorption of CCM.
Predicting ancient city sites using GEE coupled with geographic element features and temporal spectral features: a case study of the Neolithic and Bronze Age of Jianghan region
Authors: Yang Hong , Hu Qingwu , Zou Qiushi , Ai Mingyao , Zhao Pengcheng , Wang Shaohua 
Published: May 2024

Abstract

As an important birthplace of civilization in China, the Yangtze River Basin has the necessary to discover further and investigate the ancient remains, and the archaeological site prediction model is significant for discovering and investigating archaeological remains. In this paper, we focused on the ancient city sites of the Neolithic and Bronze Age in Jianghan region in the middle reaches of the Yangtze River, annotated the specific locations and ranges of 33 ancient city sites using the Google Earth Engine (GEE) cloud platform, and proposed a machine learning ancient city site prediction model by coupling geographic element features and temporal spectral features. Results indicated that the ancient city sites were recognizable in different geographic elements and separable in Sentinel-2 multispectral bands and spectral indices; the coupled time series spectral features could improve the ability of the model to recognize the regions of the ancient city sites, the percentage of pixels with a high probability of prediction (greater than 0.57) within the range of the ancient city sites was 80.0%, and the distribution of the ancient city sites could be obtained from the precise high probability regions. The model proposed can be used to predict the potential geographic locations of ancient city sites and indicate the key areas for future field archaeological survey work.
Reproductive biology of the threatened Kaempfer's Tody-Tyrant (Hemitriccus kaempferi)
Authors: Willrich Guilherme , de Farias Fernando Bittencourt , Anjos Luiz dos , Lima Marcos Robalinho 
Published: May 2024

Abstract

Knowledge on the reproductive biology of neotropical bird species is still scarce. Many species lack basic information regarding descriptions of nest and eggs, incubation and nestling period, and parental care. In the present study we explore several aspects of the reproductive biology of Hemitriccus kaempferi based on banded individuals that were monitored during two consecutive reproductive seasons (between August and December 2016 and 2017). Fieldwork was conducted in two distinct forest areas in the municipality of Joinville, Santa Catarina state, southern Brazil. A total of 21 individuals were captured and banded. We conducted a total of 178 h 04 min of focal-animal monitoring and 142 h of active nest search and found two nests. Nests resemble those already described for the genus, they are enclosed with lateral entrance, ovoid and has a superior and lateral fixation. The females were solely responsible for all the reproductive activities, including nest construction, egg incubation and parental care. Clutch size varies from 1 to 2 eggs, which are cream coloured and covered by small brown spots. Incubation period was 21–22 days and nestlings fledged after 19 days. We also present information regarding parental care, juvenile behaviour, and diet, which include 11 arthropods orders with prevalence of Lepidoptera and Coleoptera. This study adds valuable information on ecology and natural history of this endemic and enigmatic species as well as can guide further studies on phylogenetically related species.
Season Aware Solar Photovoltaic-Based Efficient EV Charging System Using A Novel JFL-BiLSTM And RF-SHO
Authors: Rajender Jatoth , Dubey Manisha , Kumar Yogendra 
Published: May 2024

Abstract

The surge in Electric Vehicle (EV) adoption has intensified energy demand, prompting the integration of Solar Photovoltaic (S-PV) systems for optimization. To address the challenge of fluctuating load demand with seasonal changes, a novel approach is proposed. This system combines Laguerre Polynomial-based Ramp Rate Method (LP-RRM) to smooth DC power from S-PV, Generalized Space Vector Modulation-based Switching Regulators (GSVM-SR) to tackle grid interruptions, and Rosenbrock Function-based Sea-Horse Optimization (RF-SHO) for optimal Charging System (CS) selection. Pre-processing the dataset identifies seasons and extracts features, which are fed into Joint Fusion Layer – Bidirectional Long Short Term Memory (JFL-BiLSTM) for load demand forecasting. The chosen CS is determined from a constructed graph based on user requests. The proposed technique effectively mitigates blackout risks and facilitates efficient EV charging operations, yielding promising results according to simulation outcomes.
Main sub-harmonic joint resonance of fractional quintic van der Pol-Duffing oscillator
Authors: Ren Zhongkai , Chen Jiazhao , Wang Tingyu , Zhang Zehua , Zhao Penghao , Liu Xiao , Xie Jiaquan 
Published: May 2024

Abstract

The main sub-harmonic joint resonance of the van der Pol-Duffing system with a quintic oscillator under dual-frequency excitation is investigated in this paper. The study examines the conditions for chaos and vibration resonance under different parameters. An approximate analytical solution for the principal sub-harmonic joint resonance of the system under dual-frequency excitation is obtained using the multi-scale method, while the Melnikov method provides necessary conditions for chaos in the system. Furthermore, based on the fast and slow variable separation method, vibration resonance of the system under various conditions is determined. Numerical simulations explore amplitude-frequency characteristics of total response at different excitation frequencies through analytical and simulation methods, with consistency between numerical and analytical results verified by plotting amplitude-frequency characteristic curves. Additionally, an analysis is conducted to investigate how fractional order, fractional differential coefficient, and cubic stiffness affect co-amplitude-frequency curves of the van der Pol-Duffing oscillator. The analysis reveals that a jump phenomenon exists in co-amplitude-harmonic resonance of this oscillator; moreover, changes in different parameters can alter both jump points and cause disappearance of such phenomena. Sub-critical fork bifurcation behavior as well as supercritical fork bifurcation behavior are studied along with vibration resonance caused by parameter variations. Results indicate that sub-critical fork bifurcation arises from changes in excitation term coefficient while supercritical fork bifurcation occurs due to fractional order variations. Furthermore, when different fractional order values are considered, there will be changes in resonance location, response amplitude gain, and vibration resonance mode within the system. The implementation of this measure enhances our comprehension of the vibration characteristics of the system, thereby refining the accuracy of the model and bolstering the stability of the system. Additionally, it serves as a preventive measure against resonance issues, which are particularly critical for mitigating the hazards associated with system resonance triggered by supercritical fork bifurcations. These hazards encompass potential structural damage and equipment failure.