bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synovial Fluid D‐Dimer Concentration in Foals with Septic Joint Disease
Authors: Ribera T. , Monreal L. , Armengou L. , Ríos J. , Prades M. 
Published: July 2011

Background:Increased synovial fibrinolytic activity (detected by increases in synovial D‐Dimer concentrations) has been observed in different joint diseases in humans and adult horses, presumably in order to minimize fibrin deposition within the joint and thus avoid its detrimental effects.Objective:To investigate fibrinolytic pathway activation in joint sepsis in foals by measuring synovial D‐Dimer concentrations.Animals:Eighteen septic foals with septic joints, 9 septic foals without septic joints, 9 systemically healthy foals with septic joint, and 3 controls are included.Methods:Prospective observational clinical study of foals admitted for septic arthritis. Synovial D‐Dimer concentration and routine synovial fluid analysis were performed. Diagnosis of joint sepsis was made whenever synovial total nucleated cell count was >30,000 cells/μL, synovial total protein >4 g/dL, and neutrophil percentage of >80%, or synovial fluid culture resulted positive. Results were compared among groups by general lineal models.Results:Synovial D‐Dimer concentration was significantly (P< .001) higher in the foals with septic joints compared with foals without joint disease (P< .001).Conclusions and Clinical Importance:Septic joint disease is associated with a marked increase of synovial D‐Dimer concentration (marked activation of the fibrinolytic activity) within the affected joint. Although further studies are needed, the measurement of synovial D‐Dimer concentration may be considered a complementary diagnostic marker of septic joint disease.
A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2Rγ
null
Mice
Authors: Boss Isaac W. , Nadeau Peter E. , Abbott Jeffrey R. , Yang Yajie , Mergia Ayalew , Renne Rolf 
Published: August 2011

ABSTRACT

MicroRNAs (miRNAs) are small noncoding RNA molecules that function as posttranscriptional regulators of gene expression. Kaposi's sarcoma (KS)-associated herpesvirus (KSHV), a B-cell-tropic virus associated with KS and B-cell lymphomas, encodes 12 miRNA genes that are highly expressed in these tumor cells. One viral miRNA, miR-K12-11, shares 100% seed sequence homology with hsa-miR-155, an oncogenic human miRNA that functions as a key regulator of hematopoiesis and B-cell differentiation. So far,
in vitro
studies have shown that both miRNAs can regulate a common set of cellular target genes, suggesting that miR-K12-11 may mimic miR-155 function. To comparatively study miR-K12-11 and miR-155 function
in vivo
, we used a foamy virus vector to express the miRNAs in human hematopoietic progenitors and performed immune reconstitutions in NOD/LtSz-scid IL2Rγ
null
mice. We found that ectopic expression of miR-K12-11 or miR-155 leads to a significant expansion of the CD19
+
B-cell population in the spleen. Subsequent quantitative PCR analyses of these splenic B cells revealed that C/EBPβ, a transcriptional regulator of interleukin-6 that is linked to B-cell lymphoproliferative disorders, is downregulated when either miR-K12-11 or miR-155 is ectopically expressed. In addition, inhibition of miR-K12-11 function using antagomirs in KSHV-infected human primary effusion lymphoma B cells resulted in derepression of C/EBPβ transcript levels. This
in vivo
study validates miR-K12-11 as a functional ortholog of miR-155 in the context of hematopoiesis and suggests a novel mechanism by which KSHV miR-K12-11 induces splenic B-cell expansion and potentially KSHV-associated lymphomagenesis by targeting C/EBPβ.
Republished error management: Paediatric dosing errors before and after electronic prescribing
Authors: Jani Yogini Hariprasad , Barber Nick , Wong Ian Chi Kei 
Published: July 2011

ABSTRACT

Objective
To compare the incidence and severity rating of dose prescribing errors before and after the implementation of a commercially available electronic prescribing system at a tertiary care children’s hospital.

Methods
Dose errors were identified using prescription review to detect errors. Severity rating was determined by five judges using a validated, reliable scoring tool. The mean score for each error was used as an index of severity.

Results
Dose prescribing errors occurred in 88 of the 3939 (2.2%) items prescribed for outpatients and inpatients, and on discharge prescriptions prior to the implementation of electronic prescribing (EP). After EP, there were 57 dose errors in 4784 (1.2%) items prescribed (1% absolute reduction (p&lt;0.001 χ2 test; 95% CI of difference in proportions −1.6% to −0.5%)). A decrease in the severity rating of dose errors was also seen: dose errors with potentially minor outcomes 35/3939 (0.89%) pre vs 21/4784 (0.44%) post (95% CI of difference in proportions −0.8% to −0.11%, p=0.009 χ2 test); moderate outcome 46/3939 (1.17%) pre vs 33/4784 (0.69%) post (95% CI of difference in proportions −0.91% to −0.08, p=0.019, χ2 test); severe outcome: 7/3939 (0.18%) pre vs 3/4784 (0.06%) post (95% CI of difference in proportions −0.31% to +0.04, p=0.11, χ2 test).

Conclusion
Electronic prescribing appears to reduce rates of dosing errors in paediatrics, but larger studies are required to assess the effect on the severity of these errors and in different settings.
In-stent restenosis after revascularization of myocardium with drug-eluting stents is accompanied by elevated level of blood plasma eosinophil cationic protein
Authors: Gabbasov Zufar A. , Kozlov Sergei G. , Imaeva Asiya E. , Saburova Olga S. , Zykov Kirill A. , Masenko Valery P. , Smirnov Vladimir N. 
Published: July 2011

The aim of this study was to assess the involvement of eosinophil cationic protein, a marker of eosinophil activation, in the development of in-stent restenosis after drug-eluting stent implantation. Follow-up angiography at 6 to 12 months was performed in 32 patients who were treated with percutaneous coronary intervention and implantation of sirolimus-eluting stents. Blood plasma levels of eosinophil cationic protein (ECP) and total immunoglobulin E (IgE) were measured by enzyme-linked immunosorbent assay and the level of C-reactive protein (hs-CRP) by high-sensitivity nephelometry. According to angiography data, in-stent restenosis occurred in 13 patients, while 19 patients did not develop it. There were no differences between the hs-CRP and IgE levels in patients with or without restenosis. In contrast, ECP level was higher in patients with restenosis compared with that in patients without restenosis [17.7 ng/mL (11.2–24.0) vs. 9.0 ng/mL (6.4–12.9), p = 0.017]. The incidence of in-stent restenoses was 63% in patients with ECP level higher than or equal to 11 ng/mL, and 19% in patients with an ECP level lower than 11 ng/mL (p = 0.019). These findings suggest that elevated eosinophil activation may play an important role in the pathogenesis of in-stent restenosis after implantation of drug-eluting stents.
AN INTEGRATED GUI-BUSINESS COMPONENT MODELING METHOD FOR THE MDD- AND MVC-BASED HIERARCHICAL DESIGNS
Authors: SONG CHEEYANG , CHO EUNSOOK , KIM CHULJIN 
Published: July 2011

Due to complex applications, such as the reactive system, the importance of graphic user interface (GUI) component modeling has increased. The existing GUI modeling methods, however, do not focus on hierarchical GUI and business component modeling based on the MDD and MVC patterns. Furthermore, there is a lack of systematic component-mapping mechanisms integrating GUI and business/DB component modeling, which consequently makes it difficult to establish a GUI component modeling process integrated with business tasks and ultimately deteriorates the reusability of GUI-business application models. This paper proposes a layered metamodel and an integrated modeling process that can hierarchically build a GUI-business component model based on MDD and MVC. Towards this end, the GUI metamodel and the component metamodel hierarchically established based on the PIM/PSM (MDD) and MVC styles are first defined. Then a GUI-business component modeling process is constructed based on these metamodels, in three modeling phases. Finally, the result of a case study in which the proposed method is applied to an ISMS system is discussed. With the use of the modeling elements and modeling process of the well-defined metamodels based on MDD and MVC, it is hoped that it can be shown that a systematic and layered GUI-business component model can be established, and that the reusability of the constructed GUI-business model can be maximized.
The Encounter
Authors: Gopinath Mohan , Castelino Edwin , Iyengar Srividya 
Published: August 2011

This case is based on real life incidents in a large international bank. There is a confrontation between an experienced officer (who does not have an MBA degree) and a newly recruited officer who is a novice to office decorum. There is a crisis because of the encounter between the strong willed experienced banker and the newly recruited one who possesses an MBA degree. There was a simmering discontent in the senior banker because she did not possess the required qualifications (degree in Business Administration) to move up the ladder. Circumstances in her younger days had forced her to take up the job in the bank but without this qualification, and the matter had rankled in her mind. Over the years, this had taken the form of a simmering dislike for everyone who possessed this degree, in spite of her best efforts to try and maintain a professional and detached relationship with the degree holders. The situation was also exacerbated by the fact that she felt that the younger employees did not treat her with the respect she deserved because of the lack of the professional degree. The case also shows the sometimes devious ways in which senior bankers who are in positions of trust can have a detrimental impact on the career of younger officers if the latter do not live up to their expectations in terms of office decorum and discipline. Experience is always a good teacher but it should be kept in mind that academic inputs brought in by employees also have their value in the success of an organization. The case does not end with a tidy conclusion and it is up to the reader to try and find possible solutions on how to resolve the issues raised.
Syriac Lexicography: Reflections on Resources and Sources
Authors: Brock Sebastian 
Published: July 2011

Abstract
In this brief survey of Syriac lexicographic tools, the first half considers the differing characters of the existing dictionaries, while the second discusses some of the more important source materials available for future work on Syriac lexicography: here mention is made of the various concordances (almost all of biblical texts) and word lists available, and of collections of some particular categories of words. By way of conclusion some practical suggestions are offered concerning how progress towards an eventual new Syriac dictionary might be compiled.
Response to Paul Flesher, 'The Aramaic Dialect of the James Ossuary Inscription'
Authors: Folmer Margaretha 
Published: July 2011

Abstract
On the basis of the distribution of two linguistic features found within this inscription, Paul Flesher has argued that it is more likely that the James Ossuary inscription comes from the Galilee or southern Judea in later centuries (most likely the fourth or fifth century). The response discusses the methodological shortcomings of Flesher?s treatment of the linguistic evidence. It is argued that the language of the inscription fits into Jewish Palestinian Aramaic of the second century CE onwards, possibly earlier.
11QPsa and the Hebrew Vorlage of the Peshitta Psalter
Authors: Carbajosa Ignacio 
Published: July 2011

Abstract
P.W. Flint suggests, in his monograph on the Qumran manuscripts of the Psalms, that the relationship between scrolls like 11QPsa and the Syriac Psalter 'may be profitably explored' because of the common readings and compositions. In this article the Psalms of Ascent (Pss. 120–134) are studied, concluding that the Hebrew Vorlage of the Peshitta does not follow the textual tradition attested in 11QPsa. The common readings should be ascribed to the translation techniques.
The New English Annotated Translation of the Syriac Bible (NEATSB): Retrospect and Prospect
Authors:   van Peursen, Romeny R.B. ter Haar ,   Salvesen,   Jenner
Published: July 2011

Abstract
At the request of several scholars and laymen, the Leiden Peshitta Institute has initiated a translation project, the so-called New English Annotated Translation of the Syriac Bible (NEATSB). This article reviews the initial discussions as well as the decisions made with regard to the actual setup of this translation at the first NEATSB seminar in 1999. It also evaluates these theoretical reflections and the editorial policy based on them from the perspective of translation techniques, and concludes with sample translations of two passages from 1 Samuel. This material will be brought up for discussion at the second NEATSB seminar, to be held in August 2004 under the title The Bible of Edessa.
Three Harsh Prophets: A Targumic Tosefta to Parashat Korah
Authors: Sysling Harry 
Published: July 2011

Abstract
In ms Paris of the Fragmentary Targums one finds lengthy introductions to the festival readings and also to the weekly sabbath readings. In one of these introductions (to Numbers 16.1ff.) a story is told about three prophets who denied their own prophecies, namely Moses, Elijah and Micah. This story is of special interest because of the quotations it contains of scriptural verses from the Prophets that are at variance with the offcial targum on the Prophets. The article o?ers a detailed analysis of the story and discusses its date and origin by comparing it to the extant parallels in rabbinic sources.
Effect of nematophagous fungi on reproduction of Meloidogyne enterolobii on guava (Psidium guajava) plants
Authors: Tigano Myrian , Ayres de Souza Silva Karla Fernanda , Martins Irene , Carneiro Regina M.D. Gomes , Hidalgo-Díaz Leopoldo , Guimarães de Sousa Mariana 
Published: July 2011

AbstractThe root-knot nematode, Meloidogyne enterolobii, is a major disease of guava, Psidium guajava, in Brazil and other countries. Egg-pathogenic fungi are considered potential biological control agents of root-knot nematodes and are associated with suppression of Meloidogyne spp. Glasshouse experiments were conducted in order to evaluate the effect of the fungi Paecilomyces lilacinus and Pochonia chlamydosporia on a population of M. enterolobii growing on guava plants. Guava seedlings of about 15-20 cm growing in plastic bags were inoculated with 10 000 eggs of M. enterolobii plant−1. Two months later, three isolates of P. lilacinus and one isolate of P. chlamydosporia were inoculated in the infested plants. The effect of the treatments was evaluated 6 months later. Although plant infection by nematodes was not attenuated, the number of eggs (g roots)−1 fell significantly. The number of egg masses infected with the fungi was inversely correlated with the number of eggs found in the roots. The most effective result (61.5% of control) was obtained with the isolate CG1003 of P. chlamydoporia, which was originally isolated from eggs of M. enterolobii in Brazil, followed by P. lilacinus (CG959 and CG1038) with about 40% of control. These fungi showed the ability to colonise healthy guava roots in glasshouse experiments. These results suggest that P. chlamydosporia can be selected as a potential biological control agent to be employed with other strategies in integrated management to control M. enterolobii on guava.
Genitive Constructions in Targum Jonathan to Samuel
Authors: Kuty Renaud 
Published: July 2011

Abstract
It is common knowledge that Classical Aramaic possesses two main devices to express the genitive. The first, the construct relation, is synthetic and involves a special form of the noun known as construct state (e.g. malkut david, “David's kingdom”). The second, analytic by nature, features the use of the particle d- and knows two variants: one that involves a proleptic pronominal suffix on the nomen regens (e.g. malkuteh d-david) and one that does not and therefore displays the nomen regens in the absolute or emphatic state (e.g. malkuta d-david). Though the expression of the genitive has previously been investigated in various types of Aramaic, the matter has never been raised with regard to the Aramaic of Targum Jonathan specifically. The present article purports to discuss the working and interactions of the genitive constructions in Targum Jonathan to Samuel. It will endeavor to identify the factors that condition their use, and attempt to demonstrate that the genitive in the Aramaic of Targum Jonathan to Samuel functions according to a largely consistent linguistic system.
A Non-Peshitta Jeremiah Citation by Aphrahat
Authors: Lund Jerome 
Published: July 2011

Abstract
The fourth century Syriac church father Aphrahat cites Jer. 31.31–32 in his Demonstrations. His citation is remarkable since it differs dramatically from the text of the OT Peshitta. This essay analyzes the citation and presents a solution. What looks at first blush like a citation of the Peshitta OT is in reality a blending of the Syriac NT citation of the OT and the OT Peshitta text. His use of Gen. 15.6 corroborates this method of OT citation.
The Sheikh Fadl Inscription in Its Literary and Historical Context
Authors: Holm Tawny 
Published: July 2011

Abstract
The fragmentary Sheikh Fadl inscription from the first half of the fifth century B.C.E. comprises the earliest narratives about the Inaros of Athribis who took part in an Egyptian rebellion against the Assyrians in the seventh century, and who is known especially from the much later 'Cycle of Inaros' in Demotic from the Ptolemaic and Roman periods. This Inaros is not to be confused with the Libyan rebel of the same name who led a revolt against the Persians in 464–454 B.C.E.; it may be significant, however, that the stories about Inaros of Athribis were perhaps written down in his time.
Translation Technique and Translating a Translation, with Special Reference to Ezekiel 8–11
Authors: van Rooy Harry 
Published: July 2011

Abstract
The Peshitta of Ezekiel had been regarded as a free translation since the time of Cornill to the Commentary of Zimmerli. Martin Mulder, however, regarded it as a fairly literal translation. The relationship of the Peshitta of Ezekiel to the Septuagint has also been described in different ways, with some scholars postulating a substantial degree of dependence of the Peshitta on the Septuagint. This paper will look at some aspects of the translation technique of the Peshitta of Ezekiel. This study demonstrates the freedom of the translator when faced with rare words and his use of idiomatic Syriac, but his fidelity to his Vorlage as well.
The Division between Western and Eastern Manuscripts in the Peshitta Psalter: An Insurmountable Obstacle for a Critical Edition?
Authors: Carbajosa Ignacio 
Published: July 2011

Abstract
At the end of the nineteenth century Alfred Rahlfs stated that the manuscripts of the Old Testament Peshitta were clearly divided into two families according to confessional criteria (following the schism between the Eastern and Western Syriac Churches). As a consequence, no critical edition could be done. One century later Piet B. Dirksen cast doubt on the classical theory saying that the schism had been of no consequence for the transmission of the text. But there was one exception: the book of Psalms, on which the old paradigm would continue to weigh. This article challenges the statement on the role of the Psalter.
The Origin of the Official Aramaic Quotative Marker l'mr
Authors: Pat-El Na'ama 
Published: July 2011

Abstract
In Official Aramaic, l'mr, the old infinitive of the verb √'mr, became the main form capable of introducing direct speech, even when there is another verbum dicendi present. The origin of the pattern has been the subject of several studies and has been assumed to be either an Aramaic innovation or a loan from Biblical Hebrew. An examination of the distribution and syntax of the form shows that it cannot be an Aramaic innovation and is highly unlikely to be borrowed from Hebrew. It is further suggested that the pattern is an Egyptian calque.
The Present State of Mandaic Lexicography I: The Mandaic Dictionary
Authors: Morgenstern Matthew 
Published: July 2011

Abstract
The Mandaic language has been used since Late Antiquity by the Mandaean community of Iraq and Iran as a spoken and literary idiom. The presently available Mandaic Dictionary, published in 1963, is a valuable reference tool that greatly advanced research into this much neglected Eastern Aramaic dialect. However, as the article seeks to highlight, both in terms of the scope of its corpus and its analysis, it does not conform to the current needs and achievements of Aramaic lexicography, and is in need of replacement. The first of two studies, the article discusses the dictionary's analysis and presentation of the linguistic data that was available to the authors at the time of its publication, indicates its weaknesses in various areas, and proposes criteria for better lexicographical analysis of the source material.
Criminal Justice for Gendered Violence and Beyond
Authors: Haynes Dina Francesca , Aoláin Fionnuala Ní , Cahn Naomi 
Published: July 2011

AbstractThis article focuses on the advancements in and limitations of international criminal law to address the range of harms experienced by women in times of armed conflict. International criminal law is an important tool, but not the only relevant structure or institution that has a role to play in addressing the underlying conditions and causes that produce systematic violence for women. The long-term success of post-conflict reconstruction rests upon understanding and legally articulating what women truly perceive as generally harmful to them, and then remedying those harms in the broadest possible sense. In assessing the influence and value of international and domestic criminal accountability for violations experienced by women, it is also important that we acknowledge law's limits. Criminal accountability has both symbolic and practical importance, but it must be combined with policy-making focused on the deep inequalities and disadvantages experienced by women in order to fundamentally transform women' lives in post-conflict societies. Feminists should be suspicious when law only addresses a fraction of transgressive sexual acts and fails to engender equality and nullify discrimination. Both are central to changing women's lives.