bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictive metabolomics of pearl millet phenotypic traits using a germplasm panel of genetic diversity
Authors: Pimentel Mariana Pinheiro Costa , Passos Alexandre Martins Abdão dos , Prigent Sylvain , Cassan Cédric , Tardin Flavio Dessaune , Ferreira Mariana Simões Larraz , Pétriacq Pierre , Santos Millena Barros 
Published: May 2024

Abstract

Introduction Pearl millet, dubbed a “Nutri-cereal”, has a high content of protein, starch, fiber, mineral and fatty acids. Its resilience in adverse agro-climatic conditions sets it apart from major cereals. Despite this, understanding how its genetic diversity affects physiological traits and metabolic responses remains limited. Predictive metabolomics, merging metabolomics with artificial intelligence, allows for the comprehensive top-down modelling —from phenotype to the mechanism— of various phenotypic traits.Objectives To discover predictive biomarkers for phenotypic traits in the Brazilian germplasm core collection of 203 genotypes of pearl millet through the combination of predictive metabolomics with machine learning.Methods Untargeted metabolomics was conducted using UHPLC-LTQ-Orbitrap-HRMS to obtain metabolite profiles, from the central and specialised metabolism of the pearl millet core collection. Generalised linear modelling with penalisation (GLMNET) was applied to explore the correlation between metabolism and phenotypic traits.Results Our model successfully predicted eight qualitative traits from the pearl millet core collection, with accuracy ranging between 74% and 87%. From, 834 potential unique biomarkers (575 annotated-ion features and 259 unknowns) have been annotated as top metabolic predictors. It is noteworthy that the majority of the top metabolic predictors were from the carbohydrate, amino acid, flavonoid, and terpene subclasses.Conclusions This is the first report on leveraging a germplasm bank of pearl millet for metabolome characterisation and subsequent predictive modelling of important agronomic traits. These outcomes hint at the robustness of employing GLMNET for predicting metabolic biomarkers crucial in selecting genotypes for future breeding programmes.
Nanoscale Covalent Organic Frameworks for Enhanced Photocatalytic Hydrogen Production
Authors: Cooper Andrew , Zhao Wei , Luo Liang , Cong Muyu , Liu Xueyan , Zhang Zhiyun , Bahri Mounib , Li Boyu , Yang Jing , Yu Miaojie , Liu Lunjie , Xia Yu , Browning Nigel , Zhu Wei-Hong , Zhang Weiwei 
Published: May 2024

Abstract

Nanosizing confers unique functions in materials such as graphene and quantum dots. Here, we present two nanoscale-covalent organic frameworks (nano-COFs) that exhibit exceptionally high activity for photocatalytic hydrogen production that results from their size and morphology. Compared to bulk analogues, the downsizing of COFs crystals using surfactants provides greatly improved water dispersibility and light-harvesting properties. One of these nano-COFs, TFP-BpyD nano-COF, shows a hydrogen evolution rate of 392.0 mmol g− 1 h− 1, which is one of the highest mass-normalized rates reported for a COF or any other organic photocatalysts. A reverse concentration-dependent photocatalytic phenomenon was observed, whereby a higher photocatalytic activity was found at a lower catalyst concentration. These materials also show a molecule-like excitonic nature, as studied by photoluminescence and transient absorption spectroscopy, which is again a function of their nanoscale dimensions. This charts a new path to highly efficient organic photocatalysts for solar fuel production.
Factors Influencing English-Speaking Anxiety Among EFL Learners: A Case Study in Cambodian Higher Education
Authors: Sam Rany , Yoeng Hak , Tieng Morin , Chiv Sarith 
Published: May 2024

Abstract

It is undeniable that most EFL learners have experienced academic difficulty in learning English; most of them live in non-English-speaking countries that use English as a foreign language, for example, Cambodia. This study has two main purposes, including: (1) to investigate the factors that cause EFL learners’ speaking anxiety in their higher education institutions; and (2) to examine the influences of anxiety factors on EFL learners’ speaking anxiety. The research employed a quantitative research method by using purposive sampling; a self-reported questionnaire was administered to 381 English students among senior students who currently study at three universities. Based on the findings of this research, there are six factors that make them feel anxious in the English foreign language classroom: lack of knowledge, lack of self-confidence, lack of self-esteem, lack of class interaction, lack of practice, and poor listening compression. Based on the findings, the researcher provides some recommendations to solve students’ English-speaking anxiety as well as improve students’ learning strategies.
Study of Core Biopsies of the Prostate with Emphasis on Prostate Carcinoma Detection Rate, Its Quantification and Relation to Serum PSA Level
Authors: Kujur Asha Lata , Pant Vinita 
Published: May 2024

Background
According to the national cancer registries, there has been a noteworthy increase in the incidence and prevalence of prostate cancer in India in recent years. Elevated serum PSA level has been found to show a strong correlation with prostate cancer in multiple studies conducted worldwide. The aim of this study was (i) to determine the percentage positivity of prostate biopsies sent to our centre and compare it with national and international data (ii) to assess the number and percentage area of TRUS cores involved by adenocarcinoma and its correlation with serum PSA levels and Gleason grade.
Material and methods
A retrospective study was done in our histopathology laboratory wherein, 130 TRUS-guided biopsies received in proper fixative from different hospitals and clinics during a period of one year from 1st January 2021 to 31st December 2021, were evaluated for histopathological diagnosis. Proper detailed history and indication for biopsy were provided along with the requisition form. Statistical analysis was carried out on the data.
Results
A total of 130 biopsy samples were included in the study. Out of which 76 were malignant (58.5 %) and 54 were benign (41.5 %). It was proven that with an increase in total serum PSA level, there was an increase in the involvement of the number of cores by the tumour. A significant correlation was seen between the total serum PSA levels and involvement of cores by more than 50 per cent of tumour, proven by ANOVA and the Fischer exact test. It was also noted that the tumour volume showed a strong correlation with the grade group in accordance with the Modified Gleason grading system.
Conclusion
Total serum PSA level in conjunction with quantification of tumour provides valuable information to the clinician regarding the spread of tumour within the gland as well as the severity of the disease.Malaria and Dengue fever are the two most common arthropod-borne diseases in tropical countries like India, and endemic areas like Mangalore. Since they share a similar clinical presentation, identifying the hematological parameters, can help differentiate between patients of malaria and dengue fever and can help with its prognosis and early treatment. This study aims to find a link between diagnostic markers that are used to discriminate between the infections, occuring in malaria-endemic areas, such as Mangalore, Karnataka.
Rare Spindle Cell Hemangioma of Bone: A Case Report
Authors: Patwardhan Leena , Sharma Sunita 
Published: May 2024

Spindle cell haemangioma (SCH), a rare vascular tumour usually appears as a cutaneous nodule and subcutaneous nodules in the extremities in adults in 4 th and 5 th decades of life. Its occurrence in bone and paediatric age group is extremely rare. We report a case of SCH arising at the lateral condyle of femur in a 16 year old female. It is important to avoid misdiagnosis as these lesions are considered to be benign, non neoplastic reactive vascular proliferations, with moderate incidence of recurrence.
Synthesis, Characterization, Antibacterial Evaluation, and Enzyme Inhibition Activity of a Novel Nitrogen-containing Heterocyclic Sulfonamide
Authors: Kong Jingyao , Zhang Xue , Xuan Guangshan 
Published: May 2024

Introduction:
Novel sulfonamides containing pyrazole and 1,2,3-triazole were synthesized,
and their inhibitory effects on six common pathogenic bacteria and COX-2 were investigated
to screen new sulfonamides antimicrobial agents and COX-2 inhibitors with better effects.

Methods:
The compounds with bacteriostatic effect were screened by using the ring of inhibition
method and MTT chromogenic method, and the mechanism of bacteriostatic inhibition and description
of bacteriostatic effect of the synthesized compounds were investigated with the aid of MOE
molecular docking simulation and Gaussian molecular weighting calculations. The in vitro inhibitory
effect of the synthesized compounds on COX-2 was studied using the phenylmethyl acetate color
development method.

Results:
The results of bacterial inhibition experiments revealed that compounds 11d and 11e had
better inhibition effects on pathogenic bacteria, especially on C. albicans, essentially the same as that
of the positive control, FLUCZ. The compounds 4f, 7b, and 11c had the best inhibitory effect by
COX-2 in vitro inhibition experiments, especially 11c, which had a better inhibitory effect than the
positive control acetazolamide.

Conclusion:
A series of derivatives obtained by introducing pyrazole and 1,2,3-triazole ring into
sulfonamides have good bacteriostatic and COX-2 inhibition effects and have the potential to be
developed as novel antimicrobial agents and enzyme inhibitors.
Awareness and Performance of Dentists Regarding Cardio-Vascular Diseases: A Report from Southeastern Iran
Authors: Kahnooji Masoomeh , Gisour Elham Farokh , Vahidi Firoozeh , Aliramezany Maryam 
Published: May 2024

Introduction
Undoubtedly, managing patients with cardiovascular disease poses a significant challenge for dentists. It is imperative for dental practitioners to possess a comprehensive understanding and adhere to specific guidelines when treating such individuals.

Objective
This study aimed to assess the awareness and performance of dentists concerning cardiovascular diseases.

Materials and Methods
This cross-sectional, analytical study involved the participation of 150 dentists from Kerman, Iran. An online questionnaire related to questions concerning cardiovascular diseases was used for data collection. The responses were collected electronically and entered into the SPSS software for analysis.

Results
Findings revealed a gender distribution of 46% male and 54% female, with an average participant age of 32.57 ± 8.44 years. The overall average awareness score of the study, standing at 51.58, did not show a statistically significant difference among the groups (p-value:0.0837). Conversely, the average performance score, totaling 38.38, showed a statistically significant difference among the three groups (P-value=0.028). Female participants notably displayed a markedly higher awareness score compared to their male counterparts. Age and work experience did not demonstrate any significant relationship with the variables examined in this study. The Pearson correlation coefficient between awareness and performance scores among the examined samples stood at r=0.164, implying a positive and significant correlation (p-value=0.045).

Conclusion
The findings from our study suggest that the awareness and performance levels of dentists in Kerman, Iran, pertaining to cardiovascular diseases, are deemed acceptable and desirable. However, it is prudent to advocate for ongoing attention and continuous training in this domain.
Analisis Sistem Pengendalian Internal Terhadap Pemberian Kredit Multiguna Dalam Mengurangi Kredit Bermasalah Pada PT. BPD Sultra Cabang Utama
Authors: Rahayuningsih Titien , Pratiwi Vira Arianti , Asraf Asraf , Rachmawati Rachmawati 
Published: May 2024

<div>Penelitian ini bertujuan untuk mengetahui penerapan sistem pengendalian internal atas pemberian kredit multiguna dalam mengurangi kredit bermasalah. Jenis penelitian yang digunakan adalah jenis penelitian deskriptif kualitatif. Data yang digunakan merupakan data primer yakni data yang dikumpulkan melalui wawancara. Hasil penelitian ini menunjukkan bahwa penerapan sistem pengendalian internal pada PT. BPD Sultra Cabang Utama sudah sangat memadai yaitu dengan diterapkannya 5 komponen pengendalian internal menurut COSO yang terdiri dari: (1) Lingkungan pengendalian, (2) Penilaian risiko, (3) Aktivitas pengendalian, (4) Infromasi dan Komunikasi, dan (5) Aktivitas pemantauan.</div><p> </p>
NiCuSBlockIoT: Sensor-based Cargo Assets Management and Traceability Blockchain Support for Nigerian Custom Services
Authors: Obasuyi, D.A.  , Yoro, R.E.  , Okpor, M.D.  , Ifioki, A.M,  , Brizimor, S.E  , Ojugo, A.A.  , 4Odiakaose, C.C.  , Emordi, F.U.  , Ako, R.E.  , Geteloma, V.C.  , Abere, R.A.  , Atuduhor, R.R.  , Akiakeme, E  
Published: May 2024

As competitive market and globalization continue to ripple a range of issues across the asset chain (i.e. safety, quality, tracing, and overall management efficiency). Pandemics are bound to occur without warning and has revealed the unpreparedness of many nations. Thus, the Nigerian Government aiming to shore up revenue/monetization via customs exercise duties to augment the nosedive in revenue of the oil sector – must formulate policies and adapt technology to harness its inherent benefits therein. Study advances a sensor-based blockchain NiCuSBlockIoT, which will provision a decision-support scheme for cargo goods traceability and asset movement on a value-chain by first ensuring that accurate records of cargo goods are registered, tagged and reported using the sensor-based units. These are then broadcasted on to the NiCuSBlockIoT as record and/or blocks via a P2P chain on the network as a decentralized framework executed on a distributed hyper-ledger fabric via smart-contract transaction logic. Result show model eliminate fraud that often accompanies a centralized scheme via its sensor-layered model that reports all such errors as data on NiCuSBlockIoT supply value chain. Keywords: BlockChain, Food supply chain, Nigerian Customs Service, NISBlockIoT framework	CISDI Journal Reference Format Obasuyi, D.A., Yoro, R.E., Okpor, M.D., Ifioki, A.., Brizimor, S.., Ojugo, A.A., Odiakaose, C.C., Emordi, F.U., Ako, R.E., Geteloma, V.C., Abere, R.A., Atuduhor, R.R. & Akiakeme, E. (2024): NiCuSBlockIoT: Sensor-based Cargo Assets Management and Traceability Blockchain Support for Nigerian Custom Services. Computing, Information Systems, Development Informatics & Allied Research Journal. Vol 15 No 2, Pp 45-64. dx.doi.org/10.22624/AIMS/CISDI/V15N2P4. Available online at www.isteams.net/cisdijournal
Implementasi Hak dan Kewajiban Masyarakat Millennial Pada Progam Taman Bacaan Masyarakat (TBM)
Authors: Yunita Sri , Sagala Angel Chasita , Sagala Annisa Azmi , Hasibuan Maria Angel , Sinaga Mariana 
Published: May 2024

Tujuan penelitian ini untuk mendeskripsikan bagaimana implementasi hak dan kewajiban warga negara khusus pada masyarakat millennial pada program Taman Bacaan Masyarakat (TBM) dengan tujuan impelemntasi agar anak anak yang ada di TBM tersebut dapat menerapkan di kehidupan sehari hari. Metode yang digunakan dalam penelitian ini adalah metode penelitian survei dengan 100 orang responden yang terlibat dalam program taman bacaan masyarakat di kelurahan Tembung, Medan. Adapun hasil penelitian yang diperoleh yaitu: (1) hak dan kewajiban memiliki peran penting dalam non-formal untuk menjaga kestabilan dan keharmonisan; (2) hak dan kewajiban di lingkungan non-formal sangat berpengaruh pada kualitas pelayanan dan kepuasan pelanggan; (3) hak dan kewajiban di lingkungan non-formal harus diimplementasikan dengan baik, untuk menjaga kestabilan dan keharmonisan; dan (4) pelayanan yang profesional dan transparan membutuhkan banyak evaluasi dan pengawasan, untuk memastikan bahwa hak dan kewajiban di lingkungan non-formal dibangun secara tepat.
The 2020 COVID-19 Financial Crisis Impact on the European Stock Markets and Economies. A Preliminary Analysis
Authors: Foo Jennifer , Witkowska Dorota 
Published: May 2024

Abstract

Research background
In mid-April 2020, the global financial markets plunged into financial crisis from the unprecedented worldwide lockdowns for an extended period.

Purpose
This paper looks at the COVID-19 pandemic impact on the selected European stock markets and economies in comparison to USA, Israel, and China. The goal of the research is to find out if the pandemic affected different national economies and capital markets in the same way.

Research methodology
An empirical investigation is conducted for daily returns from stock indexes characterizing 5 developed and 4 post-communist European stock markets together with the above mentioned 3 non-European ones, using statistical inference and a correlation analysis.

Results
Our study shows that the COVID-19 pandemic financial crisis had a similar impact on all of the analyzed economies. Although, the GDP growth rate and inflation differ among countries. GDP growth rates in 2021 did not offset the declines from the previous year in Czechia, Germany, France, Italy and the UK. GDP growth and inflation rates in 2021 are bigger in European post-communist countries than in developed countries. All markets apart from the NASDAQ100, SSE, DAX and MSCI Europe reported negative annual rates of return in 2020. The highest risk was observed in the pandemic shock period. In the pandemic stabilization period expected returns from all stock indexes (except FTSE100 and TA35) were significantly positive.

Novelty
A comparison of selected markets and economies in different stages of the pandemic. Our study shows that financial markets should now incorporate such an event caused by a pandemic as part of financial crisis studies.
Study of the Impact of War Migration of the Population on the Ukrainian and European Labour Market
Authors: Rybchak Vitalii , Verniuk Nataliia , Novak Inna , Fernos Yuliia 
Published: May 2024

Abstract

Research background
The Russian-Ukrainian war has become a significant factor that has prompted millions of Ukrainian citizens to migrate in search of safety. The demographic situation in Ukraine is deteriorating in both quantitative and qualitative dimensions. The mentioned changes are impacting the domestic and European labour markets.

Purpose
The article examines the consequences of war migration of the population for domestic and European labour markets.

Research methodology
The study covers the period between 2013 and 2023. Empirical research methods were use in the article: observation, comparison, generalization, forecasting.

Results
Ukrainian migrants presently comprise approximately 1% of the population in European Union countries and represent 15% of Ukraine’s overall demographic composition. The prevailing inclination among the majority of these migrants is not to return to Ukraine in the immediate future, with the principal determinant being identified as the prevailing sense of peril. Notably, within the age structure of Ukrainian migrants, a significant 81.2% fall within the economically productive age bracket of 18-49 years. This demographic composition sets the stage for a positive economic effect within the European Union, while concurrently engendering adverse repercussions for the domestic labour market in Ukraine.

Novelty
A three-year projection regarding the migration volumes of Ukrainians to the European Union has been delineated. Drawing upon post-war reconstruction experiences worldwide and taking into account the critical demographic landscape in Ukraine, a proposition has been put forth to synergize efforts among the government, international organizations, and donors. This collaborative endeavour seeks to establish a financial fund, wherein resources will be allocated towards the formulation of recommendations and the subsequent design and implementation of programs aimed at the restoration of the domestic labour market.
Assessing the Role of the Fintech Era on the Banking Stability of an Emerging Economy: Interaction Analysis of the Indian Banking Industry
Authors: Syed Aamir Aijaz , Grima Simon , Sood Kiran 
Published: May 2024

Abstract

Research background
The rapid expansion in recent fintech innovations has garnered researchers’ attention to evaluate its influence on the banking industry.

Purpose
In this quest, the current study conducts an interaction analysis to measure the impact of the fintech era on Indian banking stability.

Research methodology
S imilarly t o p revious s tudies, w e u se a regression analysis and a Pearson correlation on the transition period of the fintech era to measure the impact of explanatory variables on the outcome variables of the Indian banking industry. Furthermore, as a robustness test, we have also used the Generalised Method of Moments system approach. This enabled us to make comparisons with similar studies.

Results
Using annual data from 1995 to 2021, the study reveals that, compared to the first fintech era, the second era assisted in reducing NPLs and enhancing financial stability in India. The study concludes that during the second wave of the fintech revolution, through interaction analysis, explanatory variables positively influence banking stability and NPLs.

Novelty
The current study contributes toward understanding the significance of fintech development from the context of an emerging country. It also helps to interpret the importance of disruptive forces of fintech development in the banking industry.
Analysis of Pluviograms Recorded in the Area of a Phosphogypsum Heap at Wiślinka, Poland
Authors: Korzec Aleksandra 
Published: May 2024

Abstract
The paper is devoted to the long-term project concerning monitoring and stability analysis of a 40 m high phosphogypsum heap located at Wiślinka, Poland. The research presented in the paper focused on collecting and processing rainfall data, which subsequently allows us to perform numerical simulation of rainfall impact on heap’s behaviour. Such analysis requires time history of rainfall intensity, that is recorded by an automatic precipitation station. Since this is not common monitoring equipment, the characteristics of the station installed in the immediate vicinity of the heap are presented, and the data obtained in two experiments conducted in the laboratory are discussed. The analysis revealed that di erences between introduced and measured total rain are as large as 10% for very heavy rains. Moreover, the recorded maximum rainfall intensity often includes errors. The data processing procedure to obtain time history of rainfall intensity is presented on the basis of data collected in the first half of the hydrological year 2023 (the first period of the station’s operation). The total precipitation registered was 107 mm, and the maximum daily rain was only 26 mm. However, first single and multi-stage rainfall models for the Wiślinka region that would be applied into numerical simulations are presented.
Pola Pasif dalam Bahasa Indonesi: Suatu Tinjauan Sederhana
Authors: Teguh I Wayan 
Published: May 2024

Indonesian language has several functions. One of the functions of Indonesian language is as a symbol of national identity. The function as a symbol of this national identity is closely related to the statement "language is the mirror of the nation". From this statement, it is known that the nation's mindset can be understood through the language used. That is, the language used affects the way of thinking of the community. In addition, the language used also affects the way people see and understand the surrounding environment. In connection with this, this article simply reviewed one construction in Indonesian language, namely passive construction. This passive construction is considered important to be discussed (although simply) because it is not highlighted by the actors or agents of an action.