bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Personal Hygiene, Kepadatan Hunian, dan Kelembaban dengan Kejadian Skabies pada Santri Putra Pondok Pesantren Al-Aziziyah
Authors: Dzikrurrohman Mochammad Haidyr , Sabariah Sabariah , Anulus Ayu , Mulianingsih Wiwin 
Published: May 2024

ABSTRACT Scabies is a dermatological condition that causes itching sensations on the skin. High prevalence of scabies is often found in places with relatively high population density, such as boarding schools. Additionally, personal hygiene and humidity are other factors influencing the occurrence of scabies. This study aims to determine the relationship between personal hygiene, population density, and humidity with the occurrence of scabies among male students at Al-Aziziyah Islamic Boarding School. The research design used is analytical observational with a cross-sectional study. The sampling technique employed in this research is simple random sampling, with a sample size of 105 respondents calculated using the Slovin formula. The research findings indicate that 63 respondents (60.0%) experienced scabies. The variables of personal hygiene (p < 0.001), population density (p < 0.001), and humidity (p < 0.001) are factors significantly associated with the occurrence of scabies among male students at Al-Aziziyah Islamic Boarding School. There is a significant relationship between personal hygiene, population density, and humidity with the occurrence of scabies among male students at Al-Aziziyah Islamic Boarding School. Keywords: Scabies, Personal Hygiene, Population Density, Humidity, Al-Aziziyah Islamic Boarding School ABSTRAK Skabies adalah kondisi dermatologis yang menyebabkan sensasi kulit gatal. Prevalensi skabies yang tinggi ini biasanya dapat ditemukan di tempat dengan jumlah hunian yang cukup tinggi seperti pondok pesantren. Selain itu personal hygiene dan kelembaban menjadi faktor lain yang berpengaruh terhadap kejadian skabies. Penelitian ini bertujuan untuk mengetahui hubungan personal hygiene, kepadatan hunian, dan kelembaban terhadap kejadian skabies pada santri putra di Pondok Pesantren Al-Aziziyah. Jenis penelitian yang digunakan adalah observasional analitik dengan studi penelitian crosssectional. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah simple random sampling, Jumlah sampel dalam penelitian ini seteleh menghitung dengan rumus Slovin adalah 105 sampel. Hasil penelitian menunjukkan didapatkan santri yang mengalami skabies yaitu sebanyak 63 responden (60,0%). Variabel personal hygiene (p < 0,001), kepadatan hunian (p < 0,001), dan kelembaban (p < 0,001) menjadi faktor yang berhubungan dengan kejadian skabies pada santri putra Pondok Pesantren Al-Aziziyah. Terdapat hubungan signifikan antara personal hygiene, kepadatan hunian, dan kelembaban seseorang dengan kejadian skabies pada santri putra Pondok Pesantren Al-Aziziyah.Mataram. Kata Kunci: Skabies, Personal Hygiene, Kepadatan Hunian, Kelembaban, Pondok Pesantren Al-Aziziyah
Dukungan Orang Tua Berhubungan dengan Prestasi Belajar Anak di Masa Pandemi Covid-19
Authors: Marwan Marwan , Pariyem Pariyem , Rachmadany Revy Dwi 
Published: May 2024

ABSTRACT With so many people infected with Corona Virus Disease (COVID-19), the government issued a regulation on Large-Scale Social Restrictions which resulted in the teaching and learning process which is now conducted online. With these rules, parental support is needed in the child's learning process at home. Parental support is assistance given to children, especially in learning. To analyze the relationship between parental support and children's learning achievement during the COVID-19 pandemic at SDN Kartoharjo 1 Magetan. The approach used is cross sectional. The sample used by some students at SDN Kartoharjo 1 was 60 respondents, the sampling technique used cluster random sampling. From the research conducted the majority of parental support is very high with very good children's learning achievement as many as 16 respondents (26.7%). The results of the Rank Sperman test show a significant value value = 0.020 (p value = 0.020 <0.05), which means that there is a relationship between parental support and learning achievement with a coefficient of r = 0.301 which indicates a sufficient relationship. H0 is rejected and H1 is accepted, meaning that there is a relationship between parental support for children's learning achievements during the COVID-19 pandemic at SDN Kartoharjo 1 Magetan. Therefore, parental support is needed to improve children's learning achievement. Keywords: Parental Support, Learning Achievement ABSTRAK Dengan banyaknnya masyarakat yang terinfeksi Corona Virus Disease COVID-19 pemerintah mengeluarkan aturan Pembatasan Sosial Berskala Besar yang berakibat pada proses belajar mengajar yang sekarang dilakukan secara online. Dengan adanya aturan tersebut dukungan orang tua diperlukan dalam proses belajar anak di rumah. Dukungan orang tua adalah bantuan yang diberikan kepada anak terutama dalam belajar. Menganalisis hubungan dukungan orang tua terhadap prestasi belajar anak di masa pandemi covid-19 di SDN Kartoharjo 1 Magetan. Pendekatan yang digunakan adalah Cross sectional. Sampel yang digunakan sebagian siswa di SDN Kartoharjo 1 sebanyak 60 responden, tehnik sampling menggunakan cluster random sampling. Dari penelitian yang dilakukan Mayoritas dukungan orang tua sangat tinggi dengan prestasi belajar anak sangat baik sebanyak 16 responden (26,7%). Hasil uji Rank Sperman menunjukkan nilai signifikan ρ value = 0,020 (p value=0,020<0,05), yang berarti ada hubungan antara dukungan orang tua dengan prestasi belajar dengan nilai koefisien r = 0,301 yang menunjukkan hubungan cukup. H0 ditolak dan H1 diterima berarti ada hubungan dukungan orang tua terhadap prestasi belajar anak di masa pandemi COVID-19 di SDN Kartoharjo 1 Magetan. Oleh karena itu, dukungan orang tua sangat diperlukan untuk meningkatkan prestasi belajar anak. Kata Kunci: Dukungan Orang tua, Prestasi belajar
Pengaruh Terapi Murottal Terhadap Perubahan Nadi dan Kecemasan Pada Pasien Stemi di Ruangan CVCU RSUD PROF. DR. H. Aloei Saboe
Authors: Damansyah Haslinda , Umar Arifin , Pakaya Idris , Mohamad Nunung Amelia 
Published: May 2024

ABSTRACT Increased blood pressure in stemi patients due to anxiety can be seen from the patient's pulse. Treatment that can be given to stemi patients to reduce pulse rate and anxiety is murottal Al-Qur'an therapy. The purpose of this researchcapable studentsdetermine the effect of murottal therapy on pulse changes and anxiety in stemi patients in the CVCU Room at Prof. Dr. H. Aloei Saboe Regional Hospital. The research method used was pre-experimental with a one group pre-post test design on 10 stemi patients in the CVCU room at Prof. Hospital. Aloei Saboe. The results of this study show that from the paired sample t-test analysis, the significant value for pulse before and after was 0.012 (<α 0.05) and the significant value for anxiety before and after was 0.000 (<α 0.05), meaning that there was an influence of murottal Al therapy. -Qur'an on changes in pulse and anxiety in STEMI patients in the CVCU Room at Prof. Hospital. Dr. H. Aloei Saboe. Keywords: Anxiety, Murottal, Nadi, Stemi, Therapy ABSTRAK Peningkatan tekanan darah pada pasien stemi akibat kecemasan dapat diketahui dari denyut nadi pasien. Penatalaksanaan yang dapat diberikan kepada pasien stemi untuk menurunkan denyut nadi dan kecemasan yaitu terapi murottal Al-Qur’an. Tujuan penelitian ini mahasiswa mampu mengetahui pengaruh terapi murottal terhadap perubahan nadi dan kecemasan pada pasien stemi di Ruangan CVCU RSUD Prof. Dr. H. Aloei Saboe. Metode penelitian yang digunakan yaitu pra-eksperimental dengan one group pre post test design pada 10 pasien stemi di ruangan CVCU RSUD Prof. Aloei Saboe. Hasil penelitian ini menunjukan dari analisis paired sample t-test diperoleh nilai signifikan untuk nadi sebelum dan sesudah adalah 0,012 (<α 0,05) dan nilai signifikan kecemasan sebelum dan sesudah adalah 0,000 (<α 0,05) artinya ada pengaruh terapi murottal Al-Qur’an terhadap perubahan nadi dan kecemasan pada pasien STEMI di Ruangan CVCU RSUD Prof. Dr. H. Aloei Saboe. Kata Kunci: Kecemasan, Murottal, Nadi, Stemi, Terapi
In the Middle of a Reign
Authors: Limbert Mandana E. 
Published: May 2024

By the mid-1990s, twenty-five years after Sultan Qaboos came to power and in the middle of his reign, the past—and local values associated with it—garnered significant interest for many in Bahla, a medium-sized pre-Islamic oasis town in interior Oman. Townspeople organized and opened a new library for the first time and town elders wrote and copied local histories to disseminate and sell at bookshops in the town suq. Such interest in local history did not appear suddenly or out of the blue.
Beyond the Horizon and Back: The Sultan Qaboos Scholarshi
Authors: Pritt Jody 
Published: May 2024

From the start of his reign in 1970, Sultan Qaboos bin Said prioritized education for all citizens. His establishment of Oman’s first national university in 1986, Sultan Qaboos University (SQU), was a major pillar of Oman’s modernizing Nahda or “Renaissance.” Sultan Qaboos also created an external scholarship program under the authority of the newly created Department of Knowledge.
Pengaruh Campuran Probiotik dan Daun Pepaya pada Pakan Buatan (Pellet) Terhadap Pertumbuhan Ikan Nila (Oreochromis niloticus)
Authors: Haqiqi Fhaisal , Astarika Rina , Nurdiyah  
Published: May 2024

Ikan nila merupakan komoditas air tawar yang cukup banyak digemari oleh masyarakat Indonesia karena rasa dagingnya yang sangat lezat. Ikan ini memiliki kelebihan diantaranya : 1) cenderung kuat terhadap gangguan penyakit yang biasa dialami oleh jenis ikan air tawar lainnya, 2) memiliki toleransi terhadap kualitas air pada kisaran yang lebar.Beberapa factor penting yang mendasari penelitian ini adalah pembudidayaan ikan nila di Mamuju Tengah saat ini menjadi perhatian disebabkan 1) hasil produksinya masih sangat minim yaitu 82,19 ton per tahun 2022 lalu, 2) teknik pembudidayaannya kurang efisien : untuk mencapai usia panen, pemeliharaan ikan nila ini menghabiskan waktu tiga sampai empat bulan. Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui pengaruh penambahan campuran probiotik dan daun pepaya pada pakan buatan (pellet) terhadap pertumbuhan ikan nila meliputi masa pemeliharan, bobot ikan dan panjang ikan. Metode pengumpulan data menggunakan rancangan eksperimen jenis Quasi Experimental Design. Sedangkan pengambilan datanya menggunakan metode pengambilan sampel secara tidak acak dengan cara quota sampling. Data yang diperoleh dalam penelitian ini ditampilkan dalam bentuk tabel. Penyajian data menggunakan Microsoft Excel 2013. Hasil yang diperoleh dari penelitian ini antara lain : (1) pembudidayaan ikan nila dengan metode alternatif campuran pakan ini dapat ditempuh dalam kurun waktu 63 hari, (2) pemberian alternatif pakan terbaik didapatkan pada dosis 4 ml probiotik dan 25 g daun pepaya pada 100 gr pakan.
Rapid segmentation of computed tomography angiography images of the aortic valve: the efficacy and clinical value of a deep learning algorithm
Authors: Mao Yu , Zhu Guangyu , Yang Tingting , Lange Ruediger , Noterdaeme Timothée , Ma Chenming , Yang Jian 
Published: May 2024

ObjectivesThe goal of this study was to explore the reliability and clinical value of fast, accurate automatic segmentation of the aortic root based on a deep learning tool compared with computed tomography angiography.MethodsA deep learning tool for automatic 3-dimensional aortic root reconstruction, the CVPILOT system (TAVIMercy Data Technology Ltd., Nanjing, China), was trained and tested using computed tomography angiography scans collected from 183 patients undergoing transcatheter aortic valve replacement from January 2021 to December 2022. The quality of the reconstructed models was assessed using validation data sets and evaluated clinically by experts.ResultsThe segmentation of the ascending aorta and the left ventricle attained Dice similarity coefficients (DSC) of 0.9806/0.9711 and 0.9603/0.9643 for the training and validation sets, respectively. The leaflets had a DSC of 0.8049/0.7931, and the calcification had a DSC of 0.8814/0.8630. After 6 months of application, the system modeling time was reduced to 19.83 s.ConclusionFor patients undergoing transcatheter aortic valve replacement, the CVPILOT system facilitates clinical workflow. The reliable evaluation quality of the platform indicates broad clinical application prospects in the future.
Association of high vibration perception threshold with reduced renal function in patients with type 2 diabetes
Authors: Zhang Yongze , Zheng Biao , Li Yimei , Shen Ximei , Huang Lingning , Zhao Fengying , Yan Sunjie 
Published: May 2024

ObjectiveTo investigate the correlation between vibration sensory threshold (VPT) and renal function, including glomerulus and renal tubule, in patients with type 2 diabetes mellitus (T2DM).MethodsA total of 1274 patients with T2DM who were enrolled in the Department of Endocrinology of the First Affiliated Hospital of Fujian Medical University between January 2017 and June 2020 were included. Patients were grouped according to VPT levels and divided into three groups, including the normal VPT group (VPT&lt;15V), the mild-moderate elevated VPT group (VPT15~25V), and the severely elevated VPT group (VPT≥25 V). Linear correlation analysis was used to analyze the correlation between VPT and renal functions, including glomerulus markers urine microalbumin (MA) and urinary immunoglobulin G (U-IgG), and renal tubule marker α1-microglobulin (α1-MG). Chronic kidney disease (CKD) was defined according to Kidney Disease Improving Global Outcomes (KDIGO) criteria. The binary logistic regression of the relation between VPT and CKD, eGFR&lt;60 ml/min, and UACR &gt;30 mg/g were expressed.ResultsIn the mild-moderate and severely elevated VPT group, injury biomarkers of glomerulus (MA and U-IgG), renal tubule (α1-MG), and the incidence of CKD, eGFR&lt;60 ml/min, and UACR &gt; 30 mg/g were gradually increased compared with the normal VPT group. Furthermore, patients with diabetes and severely elevated VPT had significantly higher levels of MA (β=197.54, p=0.042) and α1-MG (β=11.69, p=0.023) compared to those with normal VPT. Also, patients with mild-moderate elevated VPT demonstrate significantly higher levels of MA (β=229.02, p=0.005). Patients in mild-moderate elevated VPT group (OR=1.463, 95% CI 1.005–2.127; OR=1.816, 95% CI 1.212–2.721) and severely elevated VPT group (OR=1.704, 95% CI 1.113–2.611; OR=2.027, 95% CI 1.248–3.294) are at a higher incidence of CKD and elevated levels of UACR&gt;30mg/g compared to those in the VPT normal group. Moreover, the incidence of positive Upro was notably higher in the severely elevated VPT group (OR=1.738, 95% CI 1.182–2.556). However, this phenomenon was not observed in the incidence of eGFR &lt;60 ml/min.ConclusionA higher VPT is positively associated with the incidence of CKD in patients with T2DM, particularly with elevated UACR. VPT may serve as a marker for glomerulus and renal tubule injury.
High C-reactive protein-to-albumin ratio levels are associated with osteoporosis in patients with primary biliary cholangitis
Authors: Li Yanyan , Liu Bo , Li Xin 
Published: May 2024

ObjectiveInflammation contributes to the development of metabolic bone diseases. The C-reactive protein-to-albumin ratio (CAR) is an inflammation-based marker with a prognostic value for several metabolic diseases. This study investigated the relationship between the CAR and osteoporosis (OP) in patients with primary biliary cholangitis (PBC).MethodsPatients with PBC treated at Beijing Ditan Hospital between January 2018 and June 2023 were enrolled. Logistic regression analysis was performed to investigate the factors influencing OP. The predictive value of CAR for OP was evaluated using receiver operating characteristic (ROC) curves. Moreover, a restricted cubic spline (RCS) fitted with a logistic regression model was used to analyze the relationship between CAR and OP.ResultsThe prevalence of OP among the patients with PBC was 26.9% (n = 82). CAR levels were higher in the OP group than in the non-OP group (0.33 (0.09, 0.61) vs. 0.08 (0.04, 0.18), P &lt; 0.001). Logistic regression analysis showed that CAR was an independent predictor of OP in patients with PBC (odds ratio = 2.642, 95% confidence interval = 1.537-4.540, P &lt; 0.001). CAR exhibited a good predictive ability for OP, with an areas under the curve (AUC) of 0.741. We found that individuals with CAR values &gt; 0.1 have higher odds of OP. In addition, high CAR levels were associated with an increased prevalence of fragility fractures and high 10-year fracture risk.ConclusionHigh CAR levels were associated with greater odds of developing OP, and the CAR could serve as an independent predictor of OP in patients with PBC.
External exposome and all-cause mortality in European cohorts: the EXPANSE project
Authors: Nobile Federica , Dimakopoulou Konstantina , Åström Christofer , Coloma Fabián , Dadvand Payam , de Bont Jeroen , de Hoogh Kees , Ibi Dorina , Katsouyanni Klea , Ljungman Petter , Melén Erik , Nieuwenhuijsen Mark , Pickford Regina , Sommar Johan Nilsson , Tonne Cathryn , Vermeulen Roel C. H. , Vienneau Danielle , Vlaanderen Jelle J. , Wolf Kathrin , Samoli Evangelia , Stafoggia Massimo 
Published: May 2024

BackgroundMany studies reported associations between long-term exposure to environmental factors and mortality; however, little is known on the combined effects of these factors and health. We aimed to evaluate the association between external exposome and all-cause mortality in large administrative and traditional adult cohorts in Europe.MethodsData from six administrative cohorts (Catalonia, Greece, Rome, Sweden, Switzerland and the Netherlands, totaling 27,913,545 subjects) and three traditional adult cohorts (CEANS-Sweden, EPIC-NL-the Netherlands, KORA–Germany, totaling 57,653 participants) were included. Multiple exposures were assigned at the residential addresses, and were divided into three a priori defined domains: (1) air pollution [fine particulate matter (PM2.5), nitrogen dioxide (NO₂), black carbon (BC) and warm-season Ozone (warm-O3)]; (2) land/built environment (Normalized Difference Vegetation Index—NDVI, impervious surfaces, and distance to water); (3) air temperature (cold- and warm-season mean and standard deviation). Each domain was synthesized through Principal Component Analysis (PCA), with the aim of explaining at least 80% of its variability. Cox proportional-hazards regression models were applied and the total risk of the external exposome was estimated through the Cumulative Risk Index (CRI). The estimates were adjusted for individual- and area-level covariates.ResultsMore than 205 million person-years at risk and more than 3.2 million deaths were analyzed. In single-component models, IQR increases of the first principal component of the air pollution domain were associated with higher mortality [HRs ranging from 1.011 (95% CI: 1.005–1.018) for the Rome cohort to 1.076 (1.071–1.081) for the Swedish cohort]. In contrast, lower levels of the first principal component of the land/built environment domain, pointing to reduced vegetation and higher percentage of impervious surfaces, were associated with higher risks. Finally, the CRI of external exposome increased mortality for almost all cohorts. The associations found in the traditional adult cohorts were generally consistent with the results from the administrative ones, albeit without reaching statistical significance.DiscussionVarious components of the external exposome, analyzed individually or in combination, were associated with increased mortality across European cohorts. This sets the stage for future research on the connections between various exposure patterns and human health, aiding in the planning of healthier cities.
Oropharyngeal microbial ecosystem perturbations influence the risk for acute respiratory infections in common variable immunodeficiency
Authors: Pulvirenti Federica , Giufrè Maria , Pentimalli Tancredi M. , Camilli Romina , Milito Cinzia , Villa Annalisa , Sculco Eleonora , Cerquetti Marina , Pantosti Annalisa , Quinti Isabella 
Published: May 2024

BackgroundThe respiratory tract microbiome is essential for human health and well-being and is determined by genetic, lifestyle, and environmental factors. Patients with Common Variable Immunodeficiency (CVID) suffer from respiratory and intestinal tract infections, leading to chronic diseases and increased mortality rates. While CVID patients’ gut microbiota have been analyzed, data on the respiratory microbiome ecosystem are limited.ObjectiveThis study aims to analyze the bacterial composition of the oropharynx of adults with CVID and its link with clinical and immunological features and risk for respiratory acute infections.MethodsOropharyngeal samples from 72 CVID adults and 26 controls were collected in a 12-month prospective study. The samples were analyzed by metagenomic bacterial 16S ribosomal RNA sequencing and processed using the Quantitative Insights Into Microbial Ecology (QIME) pipeline. Differentially abundant species were identified and used to build a dysbiosis index. A machine learning model trained on microbial abundance data was used to test the power of microbiome alterations to distinguish between healthy individuals and CVID patients.ResultsCompared to controls, the oropharyngeal microbiome of CVID patients showed lower alpha- and beta-diversity, with a relatively increased abundance of the order Lactobacillales, including the family Streptococcaceae. Intra-CVID analysis identified age &gt;45 years, COPD, lack of IgA, and low residual IgM as associated with a reduced alpha diversity. Expansion of Haemophilus and Streptococcus genera was observed in patients with undetectable IgA and COPD, independent from recent antibiotic use. Patients receiving azithromycin as antibiotic prophylaxis had a higher dysbiosis score. Expansion of Haemophilus and Anoxybacillus was associated with acute respiratory infections within six months.ConclusionsCVID patients showed a perturbed oropharynx microbiota enriched with potentially pathogenic bacteria and decreased protective species. Low residual levels of IgA/IgM, chronic lung damage, anti antibiotic prophylaxis contributed to respiratory dysbiosis.