bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Serum Insulin and VASPIN Levels Among Type 2 Diabetes Mellitus Patients with or Without Obesity: A Cross-sectional Analytical Study
Authors: Sihag Sapna , Mathur Ranjana , Bissa Madhu Shekhar , Bhawani Jayshree 
Published: May 2024

ABSTRACT

Introduction:
A collection of diverse conditions together referred to as diabetes mellitus frequently manifest as periods of hyperglycemia and glucose intolerance, which can be caused by insufficient insulin, improper insulin action, or both. A medical condition known as obesity is the accumulation of excess body fat to the point that it may be harmful to one’s health. It has been determined that the adipokine vaspin (visceral adipose tissue-derived serpin A12) belongs to the family of serine protease inhibitors. Insulin, a polypeptide hormone, is released by the pancreatic beta cells. This hormone is both anti-catabolic and anabolic. Insulin decreases blood glucose levels by preventing its synthesis and encouraging its storage and use.

Methodology:
In total, 125 male and female participants of various ages participated in the current study. They included 25 healthy controls, 50 non-obese and 50 obese non–insulin-dependent diabetes mellitus patients, who visited the MDM Hospital’s outpatient clinic in Jodhpur, Rajasthan. Commercially available reagents and kits were utilized for the analysis of serum insulin and vaspin samples. Standard statistical tools were utilized to evaluate the parameters.

Results and Discussion:
When results were compared with healthy participants and non-obese NIDDM subjects, obese NIDDM subjects showed statistically significant higher fasting serum insulin and serum vaspin levels (P < 0.0001).

Conclusion:
Our study’s conclusions demonstrated a strong correlation between blood insulin and vaspin levels and diabetes and obesity. Vaspin has a positive impact on insulin resistance, obesity, type 2 diabetes, and metabolic syndrome. It also enhances glucose tolerance and insulin sensitivity, reducing diabetes complications. This novel biomarker has the potential to enhance diabetes mellitus outcomes by facilitating prompt diagnosis, improved management, and reduction of complications.
Avanapparambu Maheswaran Namboothirippad – a life which preserved the knowledge of Ayurveda Vishachikitsa and Hastyayurveda
Authors: Nair Devi R , Shankar Kizhakke Meladam Pratap , Maneeri Akashlal 
Published: May 2024

Abstract
Avanapparambu Maheswaran Namboothirippad (AMN), a legendary physician of Vishachikitsa (toxicology) and Hastyayurveda (treatment of elephants through Ayurveda), has worked tirelessly to preserve these disciplines during their time of decline. Information on his life was collected through interviews with his family members and various secondary sources, including journals, books, and gray literature. His life epitomizes the transformation and upliftment that happened to Vishachikitsa in Kerala during his lifetime, along with the contributions of Ayurveda to the Indian public health care system through him. The lineage of Vishachikitsa will always pay tribute to the efforts of AMN in sustaining this knowledge in full glory during the time of its declining importance.
Acharya Priyavrata Sharma: A life that personified the term “Apta” in the modern era
Authors: Singh Neelam Kumari , Charde Vaibhav , Archana Kumari , Narasimhaji C Venkata 
Published: May 2024

Abstract
Acharya Priyavrata Sharma, who enlightened the wisdom of Ayurveda in the twentieth century, is known for shaping the postgraduate specialty of “Dravyaguna” in Ayurveda’s curriculum. His noted literary works have enriched contemporary Ayurveda literature. He published over 500 articles and 50 books and guided many scholars of Ayurveda through his visionary academic skills. He stressed the need to follow the principles of Ayurveda in research while advocating modern techniques to understand the therapeutic action of different drugs. His disciplined, passionate, and devoted life encourages us to walk the path of dedication, hard work, and diligence for the cause of Ayurveda.
Vaidya Brihaspati Dev Triguna: A healing philanthropist who was a physician to the elite
Authors: Thakur Rinky , Soman Athira 
Published: May 2024

Abstract
This life profile delves into the extraordinary life and contributions of Vaidya Brihaspati Dev Triguna, an exemplary physician and visionary in the realm of Ayurveda. His unparalleled expertise in Nadi Pariksha (Ayurvedic pulse examination) has left an indelible mark on the legacy of Ayurveda in India. The life profile meticulously unfolds through a comprehensive methodology, encompassing an extensive literature review, personal interviews with his son Vaidya Devender Triguna and members of Rashtriya Ayurveda Vidyapeeth (RAV), and insights gathered from various sources, providing a holistic understanding of his family background, education, and his national and international contributions for Ayurveda. This work is a tribute to a visionary who enriched Ayurveda and left an enduring imprint on the global landscape of holistic health.
Professor Shivcharan Dhyani - Exponent of new concepts on Ayurveda principles
Authors: Layeeq Shaizi 
Published: May 2024

Abstract
Professor Shivcharan Dhyani hailed as a beacon in the realm of Ayurveda, embodied the quintessence of an exemplary educator, researcher, and visionary. His origins in a remote village in Uttarakhand marked the beginning of a journey characterized by an insatiable thirst for knowledge and an unwavering commitment to excellence. Throughout his illustrious career, Prof. Dhyani left an indelible mark on the field with his multifaceted contributions. His pioneering research in Dravyaguna brought about a paradigm shift in Ayurvedic pharmacology. By employing rigorous scientific methodologies, he successfully bridged the gap between traditional wisdom and contemporary scientific understanding. As an educator, he transcended conventional teaching methods, fostering a deep connection with his students, and igniting their passion for learning. His eloquence and literary insight further enriched his teaching, rendering intricate concepts accessible to a diverse audience. Professor Shivcharan Dhyani’s contributions to Ayurveda transcend temporal constraints, leaving an enduring legacy that continues to inspire future generations of practitioners and researchers alike. His life serves as a poignant reminder of the transformative potential of education and the profound impact of a selflessly devoted existence dedicated to the pursuit of knowledge and service to humanity.
Biography of Pandit Divi Gopalacharlu: A revolutionary reformer of Ayurveda in preindependent India
Authors: Prasad Goli Penchala , Lavaniya Vinod Kumar , Chincholikar Mukesh Bhagwanrao 
Published: May 2024

Abstract
Pandit Divi Gopalacharlu was a legendary Ayurvedic physician who provided valuable service to Ayurveda and made a remarkable contribution to the upliftment of Ayurveda. His primary education and Sanskrit studies were held in Machalipatnam, and he completed his studies at Mahant school in Tirupati and was conferred with the title “Acharya.” He completed his Ayurveda education at Maharajah’s Ayurveda Oriental School in Mysore. The British Government recruited him as a special plague officer in 1895. He succeeded in curing and controlling the disease. His services were applauded across India for his exceptional contribution and successful management of an emergency epidemiological condition through Ayurveda. Later, he worked as Chief Physician at a free dispensary hospital of Kanyaka Parameswari Devasthanam and Charities. He established the Ashramam of Ayurveda. He started teaching Ayurveda in Telugu and tried to create awareness among people about Ayurveda. He started Ayurvedashrama Granthamala and published nearly 20 Ayurvedic texts. He wrote translations and commentaries in Telugu for the classical Ayurvedic texts. He also started a journal, Dhanvantari, to publish various research outcomes of Ayurveda. He deciphered many inscriptions that had medical importance. He was honored with many awards and worked as the president of many committees. Through Kanyaka Parameswari Devasthanam and Charities, he started a free hospital and Ayurveda college. He established Madras Ayurveda Laboratory and started manufacturing and supplying Ayurvedic medicines all over India. He prepared hundreds of medicines and set standards for the preparations. This article covers his contributions and scholarliness in detail.
Revitalizing classical Ayurveda practice in urban India—Contribution of Vaidya V. R. Padmanabha Rao
Authors: Rao Vibhuti , Sharma Ahalya 
Published: May 2024

Abstract
The renaissance of Ayurveda in contemporary times owes much to the remarkable contributions of exemplary practitioners. This paper explores the journey of Dr. V. R. Padmanabha Rao (1953–2020), an Ayurveda clinician who not only demonstrated excellence in clinical practice but also spearheaded the creation of “Agnivesha Ayurveda Anushthana,” an exclusive organization devoted to the education and training of Ayurveda doctors. Dr. Rao played a pivotal role in influencing and guiding numerous Ayurveda graduates to transition from allopathy to Ayurvedic clinical practice. His therapeutic knowledge was disseminated in a number of national and international forums, especially with regard to his successful treatment of male infertility. Central to his teachings was the concept of “How to be a successful Ayurveda clinician,” anchored in the three pillars of dual diagnosis (integrated Ayurveda and modern methods), the utilization of self-prepared classical medicines (single-herb therapy), and the cultivation of excellent clinical and administrative skills including documentation of clinical cases.
Ms. Savita Satakopan—A doyen of research in the field of Pharmacognosy
Authors: Pattona Aswathi Mohan , Kusuma Ganji , Nartunai Govindarajan , Ilavarasan Raju 
Published: May 2024

Abstract
Savita Satakopan, born in 1927, was a renowned figure in drug standardization and quality control in Ayurveda, Siddha, and Unani systems of medicine. She spent 25 years researching and analyzing Ayurvedic drugs and raw materials, focusing on identifying genuine classical crude drugs, adulteration, and developing quality standards for sample analysis. Miss. Satakopan traveled to various countries in the 1970’s to develop analytical methods for Ayurvedic drugs and published numerous papers that contributed to the quality control measures of Ayurvedic drugs. As a member of the Ayurvedic Pharmacopeia Committee, she provided guidelines and established basic principles for pharmacopeial test methods. She also advised botanical studies and contributed to the Ayurvedic pharmacopeia of India. At 94, she passed away, leaving behind a remarkable legacy in botany. Her passion for research and dedication inspired aspiring young scientists, ensuring her impact would be felt for generations to come.
Vaidyaratna Captain G. Srinivasa Murthy: A legend who revived Indian Medicine
Authors: Pattona Aswathi Mohan , Kusuma Ganji , Ilavarasan Raju 
Published: May 2024

Abstract
Captain Dr. G. Srinivasa Murthy, born in 1887, was a multifaceted personality with a strong background in both Allopathic and Indian systems of medicine. He played a significant role in the recognition and encouragement of indigenous systems of medicine. Dr. Murthy was a member of the Usman Committee formed to report on how the indigenous systems of medicine could be best developed. He produced a report, “The Science & the Art of Indian Medicine,” for the committee as his magnum opus. He founded the School of Indian Medicine in 1925 and developed an integral system combining Ayurveda and Allopathy. He was the founder president of the Indian Medical Practitioners Co-operative Pharmacy & Stores. His unselfishness and passion inspired the younger generation in the field of Indian medicine. Dr. V Narayana Swamy, a disciple of Murthy, founded the Captain Srinivasa Murthy Research Institute in 1963, which later became part of the Central Council for Research in Ayurvedic Sciences.
Pioneering contributions of Vaidyaraj Atmaram Waman Datar Shastri in Panchabhautik Chikitsa of Ayurveda
Authors: Kolhe Rasika , Pawar Gajanan , Gurav Arun 
Published: May 2024

Abstract
The resemblance between the universe and the human body is defined by five constituents, viz. earth, water, fire, air, and space are called Panchamahabhuta in Ayurveda. This fundamental concept of Panchamahabhuta is popularized by its application in diagnosis, prognosis, and treatment by Vaidya Atmaram Waman Datar Shastri, known as a pacesetter for Panchabhautik Chikitsa across India. He wrote six books on this concept. For his significant contribution to the clinical examination of Agni Samstha (seat of Agni/digestive system) and preparation of medicines, he was felicitated with “Brihattrayeeratna” by Arya Vaidya Pharmacy, Coimbatore. He founded a charitable trust in Sangli, Maharashtra. After his demise on December 25, 1995, his legacy is being carried forward by students in various ways. This study aims to delve into the life and works of Vaidya Atmaram Waman Datar Shastri. It sheds light on his invaluable contributions to the field and the enduring relevance of Panchabhautik Chikitsa in Ayurvedic practice.
Endodontic retreatment of a mesotaurodontic mandibular first molar with C-shaped configuration in a patient with multiple taurodonts: A case report and review of literature
Authors: Davaji Mina , Karimpour Sahar 
Published: May 2024

Abstract
Taurodontism is a dental anomaly characterized by an apical displacement of the pulp chamber floor, resulting in a large pulp chamber with short roots. It can be associated with certain syndromes and abnormalities, although it is common to occur as an isolated characteristic. This anomaly can occur along with other root canal system anomalies such as C-type configuration. The aim of this report is to present the successful endodontic management of a C-shaped mesotaurodontic mandibular molar and review the literature available on this matter. A 23-year-old Persian female was referred by her dental surgeon to complete the root canal treatment of her right mandibular first molar (#46). Clinical examination showed a temporized cavity with no response to pulpoperiapical tests or visible pocket depth while an elongated root trunk with slight periodontal ligament widening, incomplete obturation of the root canal system, and periapical radiolucency was evident on the intraoral radiograph. Cone-beam computed tomography (CBCT) revealed a taurodontic and type III C-shaped root canal configuration. With a diagnosis of previous treatment and asymptomatic apical periodontitis, the patient was scheduled for root canal retreatment. The same anomaly was discovered in other molar teeth on the panoramic radiograph taken before the primary treatment of tooth #46. At a 2-month follow-up session, the tooth was found asymptomatic clinically and radiographically. The past publications about the management of nonsyndromic taurodontic molars were also reviewed. The review of 29 similar articles showed that preoperative CBCT, magnification with illumination, along with active irrigation are helpful items in managing such cases.
Adoption of rotary instrumentation among general practitioners in Qassim region, Saudi Arabia: A cross-sectional survey
Authors: Alotaibi Badi B. 
Published: May 2024

Abstract

Introduction:
In contemporary dentistry, nickel–titanium (NiTi) rotary instrumentation is the standard of care. General dental practitioners (GDPs) should acquire and adopt rotary root canal instrumentation in their practices. Therefore, this study aimed to investigate the application of rotary root canal instrumentation among GDPs in the Qassim region of Saudi Arabia.

Materials and Methods:
This cross-sectional survey was conducted in the Qassim region of Saudi Arabia. An online survey was sent to GDPs registered in the Qassim region through the Saudi Dental Society contact list. It consisted of 15 questions about gender, demographics, sector, and the extent of rotary root canal instrumentation adoption in their daily practices. The Chi-square test was used to compare the frequency responses between the groups. Fisher’s exact test was used when the expected outcome was <5.

Results:
Of the 153 GDPs contacted, 81 completed the online survey. Of the 81 participants, 71.6% performed root canal treatment in their daily practice, whereas only 51.9% reported using NiTi rotary instrumentation. NiTi rotary instrumentation was adopted significantly more frequently by GDPs who graduated from non-Saudi schools, worked in the private sector, and had more than 10 years of experience. The lack of required equipment was the most commonly reported reason for not adopting NiTi rotary instrumentation. Most participants were interested in receiving training in NiTi rotary instrumentation.

Conclusion:
Almost half of the GDPs in the Qassim region did not use rotary files in their practices. Lack of undergraduate training and unavailability of equipment were the most commonly reported factors for not adopting rotary instrumentation. There was a significant interest in receiving additional training on NiTi rotary instrumentation.
Dynamic cyclic fatigue resistance of RACE EVO in S-shaped canal with different angles of access: An in vitro study
Authors: Ayad Odena Essam , El Seoud Mohammed Abou , Kataia Engy M. 
Published: May 2024

Abstract

Introduction:
Nickel–titanium instruments annually undergo improvements to enhance the cyclic fatigue lifespan, especially with challenging canals. This study examines RACE EVO instrument in an S-shaped double-curvature canal in different angles of insertion 0°, 20°, and 40° to investigate the behavior of the heat-treated instruments in challenging canals.

Materials and Methods:
A total of 30 instruments were assigned to three groups (Group 0°, Group 20°, and Group 40°). RACE EVO instruments were tested in artificial canals. The canals had two curvatures: an apical one which its parameters are 70° angle and 2 mm radius and a coronal one which its parameters are 60° angle and 5 mm radius. The test was done using a cyclic fatigue apparatus. A statistical study was done by one-way analysis of variance groups, and Tukey’s honestly significant difference/Tukey–Kramer with a level of significance (α) was adjusted to 0.05.

Results:
The time until failure was reduced by the increase in the angle of insertion; however, Group 20° and Group 40° were not significantly different. All the instruments were broken apically. The scanning electron microscopic analysis showed typical characteristics of cyclic fatigue failure.

Conclusions:
Increasing the inclination during the insertion reduced the resistance of the RACE EVO instruments to cyclic fatigue failure despite the surface heat treatment of the instrument.
Molecular Characterisation of Traditional Cashew (Anacardium occidentale L.) Populations from Nachingwea and Newala Districts in Tanzania
Authors: Chiumbi Hussein R. , Mangosongo Hashim M. 
Published: May 2024

This study assessed the genetic diversity of 120 selected cashew plants from Nachingwea and Newala traditional cashew populations, comprising of 60 cashew plants from each population. Eight Simple Sequence Repeats (SSR) makers were used to ascertain the extent of genetic variation within and between the two traditional cashew populations. Genomic DNA extraction and Polymerase Chain Reaction (PCR) were performed using standard protocols. The results showed that all SSR markers were polymorphic. Average Polymorphic Information Content (PIC), heterozygosity, number of alleles per locus, allelic frequency and Shannon’s Index were 0.540, 0.721, 3.391, 0.666 and 0.649, respectively. Analysis of molecular variance results showed that genetic variation within populations was 88% while genetic variation between populations was 12%, implying gene flow between the populations. The results further showed that the two cashew populations are genetically diverse and that Nachingwea traditional cashew population was genetically more diverse than Newala population. High genetic variation observed in the cashew populations shows that they are suitable for use in cashew breeding programmes. Thus, conservation of traditional cashew populations is recommended
Woody Species Composition, Structure, Regeneration Status and Carbon Storage of Mkulazi Forest Reserve in Tanzania
Authors: Mwakalukwa Ezekiel E. , John Christoganus , Lyimo Paulo J. 
Published: May 2024

Little is known about the status of forest condition and carbon storage potential of Mkulazi forest reserve (MFR) located in Morogoro District, Tanzania. This study was conducted to assess i) woody species composition, richness and diversity, ii) stand structure, iii) regeneration status and iv) carbon storage. Data collection for vegetation involved establishment of 100 concentric circular sample plots in the forest area of 65,710 ha. A total of 54 plant species for trees and shrubs with DBH ≥ 5 cm that belongs to 20 plant families were identified. The diversity of woody species was high (H’ = 3.11), while Stem density was 336 ± 126 stems ha-1, basal area was 9.48 ± 2.88 m2ha-1 and stand volume was 96.22 ± 32.51 m3ha-1. For the regeneration with DBH < 5 cm, a total of 26 plant species belonging to 11 plant families were identified. The diversity of woody species was also high (H’ = 3.14) and stem density was 1,198 ± 847 stems ha-1. The mean carbon stocks above ground for trees and shrubs with DBH ≥ 5 cm were 32.13 ± 10.91 Mg C ha-1 and that of below ground were 11.84 ± 3.58 Mg C ha-1. The observed high diversity of woody species, regeneration status and relatively high carbon storage potential signifies the importance of continuing protecting this reserve.
Perancangan Antarmuka Pada Aplikasi Simaku dengan Kansei Engineering dan AHP
Authors: Anwar Syahrul 
Published: May 2024

Dalam era teknologi informasi yang krusial, Universitas Muhammadiyah Cirebon berupaya memaksimalkan penggunaan Sistem Informasi Manajemen Akademik dan Keuangan (SIMAKU). Namun, perancangan antarmuka pengguna SIMAKU masih perlu peningkatan, terutama dalam layanan kemahasiswaan. Penelitian ini bertujuan untuk merancang antarmuka yang memenuhi kebutuhan emosional pengguna dengan menggunakan pendekatan Kansei Engineering. Penelitian ini membatasi penggunaan metode Kansei Engineering tipe I (KEPack) dan analisis pada pengalaman pengguna dalam aplikasi SIMAKU di Universitas Muhammadiyah Cirebon. Hasil penelitian menunjukkan 13 kata Kansei yang relevan untuk desain antarmuka SIMAKU, dengan faktor emosional "Futuristik" sebagai fokus utama. Rekomendasi elemen tampilan antarmuka dihasilkan dari analisis menggunakan metode Kansei Engineering dan AHP, memastikan kesejajaran dengan preferensi pengguna dan tujuan aplikasi. Dalam ringkasan, penelitian ini menekankan pentingnya merancang antarmuka berdasarkan respons emosional pengguna dengan Kansei Engineering. Dengan demikian, aplikasi SIMAKU dapat lebih efektif memenuhi kebutuhan pengguna dan tujuan universitas.