bluuebunny/crossref_metadata_2025_split huggingface dataset:
OC6 project Phase IV: validation of numerical models for novel floating offshore wind support structures
Authors: Bergua Roger , Wiley Will , Robertson Amy , Jonkman Jason , Brun Cédric , Pineau Jean-Philippe , Qian Quan , Maoshi Wen , Beardsell Alec , Cutler Joshua , Pierella Fabio , Hansen Christian Anker , Shi Wei , Fu Jie , Hu Lehan , Vlachogiannis Prokopios , Peyrard Christophe , Wright Christopher Simon , Friel Dallán , Hanssen-Bauer Øyvind Waage , dos Santos Carlos Renan , Frickel Eelco , Islam Hafizul , Koop Arjen , Hu Zhiqiang , Yang Jihuai , Quideau Tristan , Harnois Violette , Shaler Kelsey , Netzband Stefan , Alarcón Daniel , Trubat Pau , Connolly Aengus , Leen Seán B. , Conway Oisín 
Published: April 2024

Abstract. This paper provides a summary of the work done within Phase IV of the Offshore Code Comparison Collaboration, Continued with Correlation and unCertainty (OC6) project, under International Energy Agency Wind Technology Collaboration Programme Task 30. This phase focused on validating the loading on and motion of a novel floating offshore wind system. Numerical models of a 3.6 MW horizontal-axis wind turbine atop the TetraSpar floating support structure were compared using measurement data from a 1:43-Froude-scale test performed in the University of Maine's Alfond Wind–Wave (W2) Ocean Engineering Laboratory. Participants in the project ran a series of simulations, including system equilibrium, surge offsets, free-decay tests, wind-only conditions, wave-only conditions, and a combination of wind and wave conditions. Validation of the models was performed by comparing the aerodynamic loading, floating support structure motion, tower base loading, mooring line tensions, and keel line tensions. The results show a relatively good estimation of the aerodynamic loading and a reasonable estimation of the platform motion and tower base fore–aft bending moment. However, there is a significant dispersion in the dynamic loading for the upwind mooring line. Very good agreement was observed between most of the numerical models and the experiment for the keel line tensions.
Direct Variable Cost Comparison of Endoscopic Versus Open Carpal Tunnel Release: A Time-Driven Activity-Based Costing Analysis
Authors: Thomas Terence L. , Goh Graham S. , Beredjiklian Pedro K. 
Published: April 2024

Introduction:
To improve the delivery of value-based health care, a deeper understanding of the cost drivers in hand surgery is warranted. Time-driven activity-based costing (TDABC) offers a more accurate estimation of resource utilization compared with top-down accounting methods. This study used TDABC to compare the facility costs of open carpal tunnel release (OCTR) and endoscopic carpal tunnel release (ECTR).

Methods:
We identified 845 consecutive, unilateral carpal tunnel release (516 open, 329 endoscopic) surgeries performed at an orthopaedic specialty hospital between 2015 and 2021. Itemized facility costs were calculated using a TDABC algorithm. Patient demographics, comorbidities, surgical characteristics, and itemized costs were compared between OCTR and ECTR. Multivariate regression was used to determine the independent effect of endoscopic surgery on true facility costs.

Results:
Total facility costs were $352 higher in ECTR compared with OCTR ($882 versus $530). ECTR cases had higher personnel costs ($499 versus $420), likely because of longer surgical time (15 versus 11 minutes) and total operating room time (35 versus 27 minutes). ECTR cases also had higher supply costs ($383 versus $110). Controlling for demographics and comorbidities, ECTR was associated with an increase in personnel costs of $35.74 (95% CI, $26.32 to $45.15), supply costs of $230.28 (95% CI, $205.17 to $255.39), and total facility costs of $265.99 (95% CI, $237.01 to $294.97) per case.

Discussion:
Using TDABC, ECTR was 66% more costly to the facility compared with OCTR. To reduce the costs related to endoscopic surgery, efforts to decrease surgical time and negotiate lower ECTR-specific supply costs are warranted.

Level of evidence:
Economic and Decision Analysis Level II
CONTRIBUTION N.I. KEVORKOV IN THE DEVELOPMENT OF PARASITOLOGY AND EPIDEMIOLOGY IN CENTRAL ASIA
Authors: Ткаченко П.В. , Никишина Н.А. 
Published: April 2024

В статье представлены факты научной биографии выдающегося паразитолога ХХ века, заслуженного врача и заслуженного деятеля науки Киргизской ССР, д.м.н. профессора Н.П. Кеворкова. Показаны результаты его научной деятельности в годы работы в г. Ташкенте, г. Фрунзе и г. Курске. Проанализирован вклада Н.П. Кеворкова в изучение биологии возбудителей гименолепидоза, трихомоноза и лямблиоза, а также в профилактику и в лечение этих заболеваний, а также в формирование научных сообществ в Узбекистане, Киргизии и России.
The article presents the facts of the scientific biography of the outstanding parasitologist of the 20th century, Honored Doctor and Honored Scientist of the Kyrgyz SSR, Doctor of Medical Sciences. professor N.P. Kevorkov. The results of his scientific activity during the years of work in Tashkent, Frunze and Kursk are shown. Shown is the contribution of N.P. Kevorkov in the study of the biology of pathogens of hymenolepiasis, trichomoniasis and lyamliosis, as well as in the prevention and treatment of these diseases, as well as in the formation of scientific communities in Uzbekistan, Kyrgyzstan and Russia.
Non-Coding RNA: An Emerging Modulator of ꞵ-Globin Regulation and ꞵ-Hemoglobinopathies
Authors: Ali Hamad , Khan Faisal 
Published: April 2024

ꞵ-Hemoglobinopathies, including ꞵ-thalassemia and sickle cell anemia, are the most common autosomal receiver disorders, globally. Non-coding RNAs (ncRNAs) are derived from exons or introns of protein-coding genes or intronic regions of non-coding genes. There is significant evidence that these ncRNAs may act as protein decoys to impact a variety of biological functions, signaling, transcriptional regulators, cell differentiation, morphogenesis, and developmental regulation. The aberrant regulation of ncRNA expression serves as a hallmark of many hematological disorders, and there is solid evidence that these RNA species can play key roles in the pathogenesis of ꞵ-hemoglobinopathies. In the present review, we provide a summary of recent research findings about the role of ncRNA in globin gene regulation and ꞵ-hemoglobinopathies and their potential as therapeutic targets or prognostic and diagnostic biomarkers.
A Comparative Effectiveness and Renoprotective Effects of Hypoglycemic Drugs for Type 2 Diabetes Mellitus
Authors: Rehman Bisma , Ain Qura Tul , Bashir Fawad , Ibrahim Ahsan , Shahid Fatima 
Published: April 2024

Type 2 Diabetes Mellitus (T2DM) is a huge burden on healthcare systems globally and it can lead to impaired kidney function, albuminuria, end-stage renal disease (ESRD). T2DM impact on the kidneys could results in diabetic nephropathy (DN) or diabetic kidney disease (DKD). It increases morbidity and mortality rate, therefore, decreases the quality of life. Present treatment protocol relies on lowering glucose levels, and strict blood pressure control by targeting blockade of the renin–angiotensin–aldosterone system. Such approaches might slow-down the decline in kidney function but many patients get end-stage kidney failure, despite optimal therapy. The need for new pharmacologic strategies for T2DM, that could prevent the development of DN and safeguard the kidneys, is rising. In this article, an overview of recent clinical data pertaining to novel therapeutic approaches for the management of DN is provided. Moreover, this review evaluates comparative effectiveness of hypoglycemic drugs like sodium-glucose cotransporter-2 inhibitors (SGLT2-i), glucagon-like peptide-1 receptor agonists (GLP1-RA), dipeptidyl peptidase-4 inhibitors (DPP4-i), and finerenone in treating T2DM and their renoprotective effects. This manuscript also highlights the need for selecting suitable drugs for a patient, as the optimal treatment significantly depends upon the patient-specific conditions.
Association of Vitamin D Gene Receptor Polymorphism with Osteoporosis in Postmenopausal Women
Authors: Zubair Muhammad , Khan Saeed , Ali Akhtar , Hanif Farina , Abbas Uzair , Ahmed Bilal , Mehmood Safia , Khan Fatima 
Published: April 2024

Osteoporosis is a critical and complicated systemic musculoskeletal disorder that encompasses low bone density (LBD) and weakening of osseous tissue at a microarchitectural level. This predisposes to increased bone fragility and subsequent risk of fractures. It is frequently encountered in postmenopausal women and has also been seen in elderly men. Vitamin D synchronizes bone and calcium homeostasis in the body by modifying the transcription of target genes through the Vitamin D receptor (VDR) and thus aids calcium uptake and bone-forming proteins. The main objective of the present research was to study the relationship of single nucleotide polymorphisms (SNP) (rs1544410 G>A) of the VDR gene with postmenopausal women who have osteoporosis in a Pakistani cohort. A total of 100 postmenopausal women, 50 without osteoporosis to be in the control group, and 50 with osteoporosis as cases, were enrolled in this study. The patients had no immediate family connections with each other. All the patients underwent BMD measurements at the lumbar spine and femoral neck by dual-energy X-ray absorptiometry scan for their diagnosis of osteoporosis based on World Health Organization (WHO) criteria (T score < -2.5 SD). A total of 25 participants had at least one allele of rs1544410, of which 14 were cases and 11 controls. The number of heterozygous and homozygous were present with similar ratios in both groups (p=0.973). Age was noted to be correlated with osteoporosis (OR: 1.06; 95%CI: 1.004-1.12), (P<0.031). It was also observed that cases had a notably lower weight than the control group (P<0.0001) and the overall body mass index of cases was significantly low in comparison to control (P<0.0001). Moreover, average BMD of femoral and BMD lumbar were notably greater among the control group (P<0.0001) as compared to cases. The SNP (rs1544410) is not significantly associated with BMD but significantly correlated with age which was identified as a risk factor while body mass index was found to be a protective factor for osteoporosis
STATE OF ECONOMIC SECURITY AND DIRECTIONS OF RESTORATION SOCIO-ECONOMIC DEVELOPMENT AND FOOD SECURITY IN THE CONDITIONS OF WAR
Authors: Dankevych Andrii , Stoyanova-Koval Svitlana , Polova Olena , Los Zoriana , Burdeina Nadiia , Kazak Oksana 
Published: April 2024

The purpose of the article is to determine the state of economic security, ways to ensure its level, and ways to restore socio-economic development under the cumulative impact of threats. In order to realize this goal, an expert assessment of the components of economic security provided and the need to take into account the component of military-economic security indicated. It indicated that the task of neutralizing threats to military and economic security opens up new windows of opportunity, in particular opportunities in ensuring socio-economic development. Prerequisites for the use of opportunity windows are defined. The dynamic nature of threats of war that require institutional measures for permanent monitoring of dynamic threats, their operational analytical assessment and the introduction of tactics to neutralize threats and reduce their long-term negative impact, are indicated. An analysis of the state economic security provided, directions for improving this state by components of economic security indicated. The main factors on which the well-being of the country's population depends are determined, the effects of crises on the indicators of the levels of income and expenditure of the population analyzed, and the drivers of the deterioration of well-being are established. It noted that the deterioration of the socio-economic situation of households led to the narrowing of the domestic market, which had a negative impact on the functioning of SMEs. It indicated that this created a negative inverse multiplier effect on the well-being of the population. The negative effects of the crisis, which led to a reduction in production volumes in the agricultural sector, were identified. It indicated that this significantly limited the ability of the branch to fulfil food security tasks. Proposed ways to reduce the negative impact of war on agricultural production to ensure food security. The directions and recommendations for economic and food security and restoring socio-economic development are specified.
BOAS PRÁTICAS NO PROCESSAMENTO DOS PRODUTOS PARA A SAÚDE ATRAVÉS DE EDUCAÇÃO PERMANENTE EM UM CENTRO DE MATERIAIS DE ESTERILIZAÇÃO: RELATO DE EXPERIÊNCIA
Authors: Corrêa Kariciele Cristina , Santos Ana Luiza Vieira Loiola , Sousa Kássia Santos , Oliveira Michelle Pinheiro de , Lima Júnior Antônio José de 
Published: April 2024

A Educação Permanente em Saúde (EPS) é essencial na prevenção de agravos e promoção a saúde. Uma vez que, este fator sai do contexto do saber científico e engloba diversos alicerces entre teoria e prática, entre a realidade e a experiência/aprendizagem de cada um. Dessa forma, quanto mais conhecimento a respeito da realidade de determinado ambiente, maior a probabilidade de melhoria no processo de trabalho, na qualidade da assistência prestada. Objetivo: relatar a experiência exitosa de educação permanente em saúde no Centro de Material e Esterilização (CME) para profissionais de enfermagem do Hospital de Clínicas da Universidade Federal de Uberlândia (HC-UFU) vinculado a Empresa Brasileira de Serviços Hospitalares (EBSERH). Método: relato de experiência, descritivo. Resultado: realizado educação permanente para todos os profissionais de enfermagem acerca de todos os protocolos e rotinas do CME. Conclusão: O processamento de materiais é complexo e dinâmico, e diante desta realidade faz-se necessário continua e permanente a educação com o intuito de propagação de informações profissionais enfocando teoria e prática para melhoria da assistência prestada. Acredita-se que a educação permanente aos profissionais fortaleça o trabalho dos mesmos enquanto atores importantes nesse processo e que as discussões tenham despertado o desejo de um novo modo de pensar-fazer, sendo crítico e reflexivo.
التحالفات الاستراتيجية مدخل لمعالجة الصدمات الاستراتيجية: دراسة لآراء عينة من القيادة الادارية لشركات المقاولات العاملة في مدينة الموصل
Authors: بهجت Yaser 
Published: April 2024

يهدف البحث لتوضيح التأثير الذي تمارسه التحالفات الاستراتيجية وابعاده الممثلة بـ (شراكة سلسلة القيمة، ترتيب الترخيص، مشارع مشتركة، اتحاد الخدمة المتبادلة) في الصدمات الاستراتيجية وابعاده الممثلة بـ (عامل البيئة الصناعية (تقلب سعر الصرف)، عامل البيئية المؤسسية (قيود الميزانية الناعمة تقابلها القوية)، قدرات الشركة (الرافعة المالية المنخفضة مقابل العالية)) والعلاقة بينهما، وكان الميدان المبحوث شركات المقاولات العاملة في مدينة الموصل ( المدرجة ضمن اتحاد المقاولين العراقيين/ فرع نينوى)، التي تم اختيارها لإجراء الجانب التطبيقي للبحث، وتم توزيع الاستمارة الاستبيان الالكترونية على الميدان المبحوث عبر تطبيق الواتساب الخاص بالمقاولين العاملين في مدينة الموصل وتم الحصول على (98) أجابه عن طريق الرابط الالكتروني الذي اعد لهذا الغرض، وتكون المجتمع البحثي من المدراء العامين لشركات المقاولات، وتم اعتماد المنهج الوصفي التحليلي في البحث، ووظفت البرمجية الاحصائية (spss.v.27) لعمليات التحليل الاحصائي للبيانات التي تم جمعها، وكانت ابرز النتائج وجود علاقة عكسية بين كل من التحالفات الاستراتيجية والصدمات الاستراتيجية، كما يوجد اثر معنوي بين التحالفات الاستراتيجية في الصدمات الاستراتيجية.
تأثير الإرهاب في سلوك أسعار الأسهم: دراسة حدث لعينة من الشركات السياحية المدرجة في سوق العراق للأوراق المالية
Authors: عيسى Jabar , جبر Shatha , داود Fadel 
Published: April 2024

تهدف هذه الدراسة الى بيان تأثير الإعلان عن توزيع الأرباح في ضل لا تماثل المعلومات وفي ضل ظاهرة الإرهاب لغرض التنبؤ بأسعار الأسهم للشركات المدرجة في سوق العراق للأوراق المالية، تَّم تطبيق الدراسة على عينة من مختلف قطاعات السوق مع مراعاة التنوع في القطاعات شملت (1) شركة سد الموصل استوفت شروط الدراسة والتي حَددت الشركات التي وزعت أرباح لسنتين متتاليين (2014 -2015)، وتَّم استعمال أُسلوب دراسة الحدث بنافذة حدث (40) يوم بمدة (20) قبل وبعد الحدث لقياس لا تماثل المعلومات، إذ تم اعتماد أسلوب التنبؤ للتّعرف على اّلاثار المستقبلية لقرار مقسوم الارباح على قرارات المستثمرين في ضل ظروف عدم الاستقرار ، إضافة الى استعمال أسلوبين احصائيين لاختبار فرضيات الدراسة هما أسلوب تحليل الانحدار وأسلوب السيناريوهات وتوصلت الدراسة الى مجموعة من الاستنتاجات أهمها امكانية تحقيق عوائد غير عادية بالاعتماد على المحتوى المعلوماتي لمقسوم الارباح كما أن هنالك تأثيرًا ذي دلالة احصائية لقرار مقسوم الأرباح في لا تماثل المعلومات ويساهم أسلوب السيناريو في التنبؤ بأسعار الأسهم بشكل افضل من الأسلوب التقليدي، ومن اهم التوصيات التي توصلت اليها الدراسة ضرورة اعتماد الأساليب العلمية لقياس تأثير الأحداث الإرهابية المؤثرة الخاصة بالسوق على دقّة النتائج المالية ولاسيمّا استخدام نماذج رياضية لقياس تأثير الأحداث الخاصة بالسوق على أسعار الأسهم كذلك يٌفضل اعتماد أُسلوب السيناريو في التنبؤ بأسعار الأسهم والأداء المالي واعتماده كنموذج يقدم خيارات متعددة أمام القرارات المالية فضلاً عن عدم الاكتفاء بالعائد غير العادي كأداة واحدة فقط لاتخاذ قرارات الاستثمار بل يجب أن يؤخذ بنظر الاعتبار العوامل الأخرى مثل المخاطرة.
Chronic Serous Chorioretinopathy: A Case Study
Authors: Hunter Amanda , Carrion Justin , Loporchio Salvatore , Greenberg Paul 
Published: April 2024

Introduction Chronic central serous chorioretinopathy (CSCR) is characterized by persistent subretinal fluid that disrupts the outer layers of the retina and may lead to complications such as: outer retinal atrophy, increased risk of choroidal neovascularization (CNVM) and the potential for permanent vision loss. This report describes the clinical features of chronic CSCR. Case Presentation A 73-year-old male with a history of systemic steroid and inhaler use presented for a routine eye exam without visual complaints. Examination findings included normal visual acuity in both eyes and multiple areas of retinal hyper and hypopigmentation along the arcades with no macular involvement in the right eye; the left eye was unremarkable. Fundus photography and optical coherence tomography showed localized areas of outer retinal disruption and thinning near the optic nerve head and along the corresponding retinal areas of irregular pigmentation in the right eye; the left eye was unremarkable. Discussion In chronic CSCR, structural changes in the retina can lead to retinal dysfunction and permanent vision loss. Treatment options for chronic CSCR include photodynamic therapy, intravitreal anti-vascular endothelial growth factor therapy, or systemic steroid receptor blockers. Visual prognosis varies depending on the severity of the disease, age of onset, risk of CNVM and the degree of outer retinal degeneration. Conclusion Patients with chronic CSCR are at risk for permanent vision loss. The structural changes in the outer retina also increase the risk for CNVM. Hence, it is important that patients with chronic CSR receive regular eye examinations and are educated on the role of regular Amsler grid testing.
Rurbanisme o el reequilibri del territori : U6T. 2, Solsonès, Segarra, Alta Anoia
Authors: Franquesa Sànchez Jordi 
Published: April 2024

La realitat dels entorns rurals és extremadament polièdrica, ja que convergeixen diverses qüestions que s’entrellacen i afecten constantment, incidint a més sobre territoris molt variats i únics. Al mateix temps, també presenta considerables desafiaments, com l’envelliment demogràfic, les disparitats socials i les dificultats d’accés als serveis essencials i a l’habitatge. Aquest segon document de la col·lecció busca proporcionar una nova perspectiva reflexiva sobre els nuclis rurals, amb l’objectiu de proporcionar criteris per a restablir un equilibri territorial necessari i millorar la qualitat de vida en les comunitats rurals.
The reality of rural environments is extremely multifaceted, since several issues converge that are constantly intertwined and affected, also in very varied and unique territories. At the same time, it also presents considerable challenges, such as the ageing of the population, social disparities and difficulties in accessing essential services and housing. This second document of the collection seeks to provide a new reflective perspective on rural nuclei, with the aim of proposing criteria to restore a necessary territorial balance and improve the quality of life in rural communities.
Partial least square structural equation modellingâ' use in information systems
Authors: Macire KANTE  , Christopher Chepken  , Robert Oboko  
Published: April 2024

The purpose of many studies in the field of Information Systems (IS) research is to analyse causal relationship between variables. Structural Equation Modelling (SEM) is a statistical technique for testing and estimating those causal relationship based on statistical data and qualitative causal assumption. Partial Least Square Structural Equation Modelling (PLS-SEM) is the technique that is mostly used in IS research. It has been subject to many reviews either in confirmatory or exploratory settings. However, it has recently emerged that PLS occupies the middle ground of exploratory and confirmatory settings. Thus, this paper intends to propose an updated guideline for the use of PLS-SEM in Information Systems Research in exploratory settings maintaining interpretability. A systematic literature review of 40 empirical and methodological studies published between 2012 and 2016 in the leading journal of the field guide Â future empirical work.
The Six Right Principles of Drug Administration to Patients with Diabetes Mellitus in Hospitals: A Case Study
Authors: Afandi Alfid Tri , Maula Muthiatul , Asmaningrum Nurfika , Putrha Gede Dharmawan 
Published: April 2024

Background: About one-third of adverse events are drug-related medication administration errors (MAE). One method to improve drug administration safety is the application of the six rights of drug administration which include right patient, right drug, correct dose, right time, right route, and proper documentation. Nurses must apply it generously and nursing professional students must be able to use it well too. Purpose: The purpose of this case study is to compare the application of the six right medicine principles between nursing and nursing professional students to Mrs. E with Diabetes Mellitus in Hospital. Methods: This case study uses a quantitative study approach with a comparative descriptive design. Data were obtained through observation for seven days with an observation measuring instrument for applying the six correct drug administration are consist of 33 statements. Respondents were obtained from purposive sampling consisting of 7 Nursing Profession students at the Faculty of Nursing, University of Jember, and seven nurses at the Hospital. Results: The difference in applying the six right principles of drug administration to Mrs. E for seven days (14 shifts) by 11 students and nurses (4.8%). Conclusion: An indicator that still really needs to be improved by students and nurses is the true indicator of patients who are still below 50%. Meanwhile, the other indicators have achieved a total implementation of >70%.