bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Faktor-Faktor Kepuasan Kerja Terhadap Kinerja Dosen PTS di Bogor
Authors: Pratomo Anton Widio , Fitriyah Idah , Gendalasari Gen Gen 
Published: June 2024

The purpose of this study was to test and analyze the effect of job satisfaction factors consisting of the work itself (X1), salary (X2), promotion opportunities (X3), supervision (X4) and co-workers (X5) on lecturer performance and the influence of variables X1, X2, X3, X4 & X5 simultaneously on lecturer performance. This study uses primary data through a survey of as many private university permanent lecturers (PTS) in Bogor. The collected data was processed and analyzed using SPSS software. From the results of this study indicate that; (1) work has a positive and significant effect on the performance of permanent lecturers at PTS in Bogor; (2) salary has no effect on the performance of permanent lecturers at PTS in Bogor; ; (3) promotion opportunities have no effect on the performance of permanent lecturers at PTS in Bogor; (4) supervisors have a positive and significant effect on the performance of permanent lecturers at PTS in Bogor; (5) colleagues have a positive and significant effect on the performance of permanent lecturers at PTS in Bogor; (6) variable X (factors of job satisfaction) as a whole is positive and significant to the performance of PTS lecturers in Bogor by 50.1%

Keywords: work, supervision, colleagues, performance
Rovibrational Transitions in HCl due to Collisions with H2: Spin-free and Hyperfine-resolved Transitions
Authors: Hoffman Daniel , Taylor Josiah , Price T. J. , Forrey Robert C. , Yang B. H. , Stancil P. C. , Zhang Z. E. , Balakrishnan N. 
Published: June 2024

Abstract
Hydrogen chloride (HCl) is a key repository of chlorine in the interstellar medium. Accurate determinations of its abundance are critical to assessing the chlorine elemental abundance and constraining stellar nucleosynthesis models. To aid in modeling recent and future observations of HCl rovibrational spectra, we present cross sections and rate coefficients for collisions between HCl and molecular hydrogen. Transitions between rovibrational states of HCl are considered for temperatures ranging from 10 to 3000 K. Cross sections are computed using a full dimensional quantum close-coupling (CC) method and a reduced dimensionality coupled-states (CS) approach. The CS results, benchmarked against the CC results, are used with a recoupling approach to calculate hyperfine-resolved rate coefficients for rovibrational transitions of HCl induced by H2. The rate coefficients will allow for a better determination of the HCl abundance in the interstellar medium and an improved understanding of interstellar chlorine chemistry. We demonstrate the utility of the new rate coefficients in a nonthermodynamic equilibrium radiative transfer model applied to observations of HCl rovibrational transitions in a circumstellar shell.
eDNA-based survey of the marine vertebrate biodiversity off the west coast of Guadeloupe (French West Indies)
Authors: Haderlé Rachel , Bouveret Laurent , Chazal Jordane , Girardet Justine , Iglésias Samuel , Lopez Pascal-Jean , Millon Cédric , Valentini Alice , Ung Visotheary , Jung Jean-Luc 
Published: June 2024

In the marine environment, knowledge of biodiversity remains incomplete for many taxa, requiring assessments to understand and monitor biodiversity loss. Environmental DNA (eDNA) metabarcoding is a powerful tool for monitoring marine biodiversity, as it enables several taxa to be characterised simultaneously in a single sample. However, the data generated by environmental DNA metabarcoding are often not easily reusable. Implementing FAIR principles and standards for eDNA-derived data can facilitate data-sharing within the scientific community.
This study focuses on the detection of marine vertebrate biodiversity using eDNA metabarcoding on the leeward coast of Guadeloupe, a known hotspot for marine biodiversity in the French West Indies. Occurrences and DNA-derived data are shared here using DarwinCore standards combined with MIMARKS standards.
Expanding geographic distribution knowledge of Galerina marginata (Batsch) Kühner (Agaricales, Hymenogastraceae) with a novel Antarctic record
Authors: Bertazzo-Silva Fernando Augusto , Putzke Jair , Furlan-Lopes Cassiane , D'ávila Maricia , Costa Alice , Carvalho Evelise , Zorzi Ana , Schaefer Carlos 
Published: June 2024

The investigation of Agaricales diversity in the Antarctica is limited, with only seven genera reported for the region. Galerina stands out as the genus with the highest species diversity, including 12 species in Antarctica. This research reports the presence of G. marginata in the region, providing the first complete morphological description for the specimen developing in Antarctica. Sampling was conducted during the Austral summer of 2022/2023 as part of the XLI Brazilian Antarctic Operation in Point Smellie, Byers Peninsula, Livingston Island, South Shetland Archipelago, Antarctica. Phylogenetic relationships reconstructed by Maximum Likelihood demonstrate that G. marginata forms a monophyletic clade with over 60% bootstrap support in most branches. The isolate in this study was found to be internal to the main cluster. Evolutionary reconstructions using the Maximum Likelihood method indicate that the branches correspond to the Antarctic isolate being an internal clade within the marginata group. Recording fungal populations in polar regions offers information about their adaptation and survival in inhospitable environments. Understanding the species' distribution in Antarctica encourages future investigations into its ecology and interactions with other organisms. Here, data are presented to establish an initial foundation for monitoring the G. marginata population in Antarctica and assessing the potential impacts of climate change on its development and survival in the forthcoming years.
We report the third occurrence of Galerina marginata (Batsch) Kühner in Antarctica and provide, for the first time, a comprehensive morphological description of an individual of the species for the Antarctic continent, accompanied by phylogenetic analyses and comprehensive discussions regarding its diversity and global distribution.
A Broad-specificity Neutralizing Nanobody against Hepatitis E Virus Capsid Protein
Authors: Wang Xueting , Sheng Yamin , Ji Pinpin , Deng Yingying , Sun Yani , Chen Yiyang , Nan Yuchen , Hiscox Julian A , Zhou En-Min , Liu Baoyuan , Zhao Qin 
Published: June 2024

Abstract
Hepatitis E virus (HEV) is a worldwide zoonotic and public health concern. The study of HEV biology is helpful for designing viral vaccines and drugs. Nanobodies have recently been considered appealing materials for viral biological research. In this study, a Bactrian camel was immunized with capsid proteins from different genotypes (1, 3, 4, and avian) of HEV. Then, a phage library (6.3 × 108 individual clones) was constructed using peripheral blood lymphocytes from the immunized camel, and 12 nanobodies against the truncated capsid protein of genotype 3 HEV (g3-p239) were screened. g3-p239-Nb55 can cross-react with different genotypes of HEV and block Kernow-C1/P6 HEV from infecting HepG2/C3A cells. To our knowledge, the epitope recognized by g3-p239-Nb55 was determined to be a novel conformational epitope located on the surface of viral particles and highly conserved among different mammalian HEV isolates. Next, to increase the affinity and half-life of the nanobody, it was displayed on the surface of ferritin, which can self-assemble into a 24-subunit nanocage, namely, fenobody-55. The affinities of fenobody-55 to g3-p239 were ∼20 times greater than those of g3-p239-Nb55. In addition, the half-life of fenobody-55 was nine times greater than that of g3-p239-Nb55. G3-p239-Nb55 and fenobody-55 can block p239 attachment and Kernow-C1/P6 infection of HepG2/C3A cells. Fenobody-55 can completely neutralize HEV infection in rabbits when it is preincubated with nonenveloped HEV particles. Our study reported a case in which a nanobody neutralized HEV infection by preincubation, identified a (to our knowledge) novel and conserved conformational epitope of HEV, and provided new material for researching HEV biology.
Distinct Localization, Transcriptional Profiles, and Functionality in Early Life Tonsil Regulatory T Cells
Authors: Verma Shivali , Bradley Marissa C , Gray Joshua , Dogra Pranay , Caron Daniel P , Maurrasse Sarah , Grunstein Eli , Waldman Erik , Jang Minyoung , Pethe Kalpana , Farber Donna L , Connors Thomas J 
Published: June 2024

Abstract
CD4+ regulatory T cells (Tregs) are key orchestrators of the immune system, fostering the establishment of protective immunity while preventing deleterious responses. Infancy and childhood are crucial periods of rapid immunologic development, but how Tregs mediate immune responses at these earliest timepoints of human life is poorly understood. In this study, we compare blood and tissue (tonsil) Tregs across pediatric and adult subjects to investigate age-related differences in Treg biology. We observed increased FOXP3 expression and proportions of Tregs in tonsil compared with paired blood samples in children. Within tonsil, early life Tregs accumulated in extrafollicular regions with cellular interactions biased toward CD8+ T cells. Tonsil Tregs in both children and adults expressed transcriptional profiles enriched for lineage defining signatures and canonical functionality compared with blood, suggesting tissue as the primary site of Treg activity. Early life tonsil Tregs transcriptional profiles were further defined by pathways associated with activation, proliferation, and polyfunctionality. Observed differences in pediatric tonsil Treg transcriptional signatures were associated with phenotypic differences, high proliferative capacity, and robust production of IL-10 compared with adult Tregs. These results identify tissue as a major driver of Treg identity, provide new insights into developmental differences in Treg biology across the human lifespan, and demonstrate unique functional properties of early life Tregs.
Understanding Psychosocial Functioning, Caregiver Burden, and Neuropalliative Care in Parkinson’s Disease – A Mixed-Methods Study
Authors: Sharma Prerna , Baruah Upasana , Yadav Akanksha , Kushwaha Suman , Dhamija Rajinder K. 
Published: June 2024

Background:
Despite advancements in treatment, patients with Parkinson’s disease (PD) experience a range of symptoms that affect their quality of life. There is a need to integrate neuropalliative care into standard care. The aim of the study is to understand the psychosocial functioning in persons with PD and explore their caregivers’ burden.

Methods:
The study utilizes a mixed-methods design where 50 patient–caregiver dyads attending the outpatient services of the movement disorder clinic at a tertiary care hospital were measured on psychosocial functioning and caregiver burden and palliative care outcomes for a period of 6 months. Focus group discussions were conducted with 18 patient–caregiver dyads to understand the needs of palliative care.

Results:
It was found that caregiver burden was positively correlated with palliative care outcomes scores of patients (r = 0.586) and caregivers (r = 0.675) and psychosocial functioning was positively correlated with palliative care outcomes of patients (r = 0.708). The psychosocial functioning score was higher among female patients (indicating worse functioning) than males, and female caregivers experienced significantly higher caregiver burden. The qualitative findings reveal that there is a substantial gap in awareness about palliative care, lack of information, presence of stigmatizing beliefs, and lack of adequate accessibility to palliative facilities.

Conclusion:
The study lays the foundation for future PD neuropalliative care research, guiding interventions, and exploration of regional variations in PD experiences in India. There is a need to address caregiver burden in PD in India.
Effect of topical brinzolamide on visual function and waveform in patients of infantile nystagmus syndrome: A randomized control trial
Authors: Yadav Bhupendra , Saxena Rohit , Dhiman Rebika , Kochhar Kanwal P. , Patil Ashlesh , Sharma Pradeep , Sihota Ramanjit , Tandon Radhika 
Published: June 2024

Purpose:
To evaluate the effect of topical carbonic anhydrase inhibitor (brinzolamide) versus placebo on visual function and waveforms in infantile nystagmus syndrome (INS).

Design:
Prospective, placebo-controlled, double-blind, cross-over study.

Methods:

Setting- A tertiary eye care center. Patients- Cases of idiopathic INS with and without abnormal head posture aged ≥10 years who had not received previous treatment for nystagmus. Intervention- Patients were randomized into two groups. Group 1 was given placebo for 3 months, and after a washout period of 7 days started on topical brinzolamide for the next 3 months. In group 2, the order was reversed. The drops were administered topically three times (every 8 hours) in both eyes. Outcome measure- Binocular best corrected visual acuity (BCVA) using the ETDRS chart, eXpanded nystagmus acuity function (NAFX) score and INS waveforms obtained from eye movement recordings, intraocular pressure (IOP) by Goldmann applanation tonometer, near stereopsis by TNO stereo test, and change in abnormal head posture before and after intervention in the null position.

Results:
A total of 29 cases completed the study (23 with abnormal head posture; 6 without abnormal head posture)

.
A significant improvement was noted in INS waveform characteristics, mean NAFX score (P < 0.001), and mean binocular visual acuity (P < 0.001) with topical brinzolamide in comparison to baseline as well as placebo. No significant change in head position and stereopsis was noted. No side effects were reported with 3 months of brinzolamide therapy.

Conclusions:
While brinzolamide shows improvement in visual acuity and NAFX score in idiopathic INS, its clinical significance needs further evidence.
Aberration change after scleral lens wear in eyes with pellucid marginal degenerations
Authors: Dutta Ronit , Iyer Geetha , Srinivasan Bhaskar , Iqbal Asif 
Published: June 2024

Purpose:
To investigate the impact of scleral lenses (SLs) on higher-order aberrations (HOAs), corrected distance visual acuity (CDVA), and contrast sensitivity (CS) in pellucid marginal degeneration (PMD) eyes.

Methods:
SLs were fitted in 24 eyes diagnosed with PMD. CDVA, CS, and HOAs were measured at baseline and with the lens on the eye. The HOAs were measured using an i-Trace aberrometer.

Results:
A statistically significant improvement was noted in CDVA (P < 0.001) with BSS lenses (0.05 ± 0.04) compared to baseline (0.42 ± 0.06). Front surface eccentricity 1 (FSE1) lens provided the best CDVA in most of the eyes. The baseline CS of 1.24 ± 0.74 improved to 1.58 ± 0.48 with SL and reported a statistically significant improvement (P < 0.001) and a gain of 6 letters. The baseline higher order-root mean square (HO-RMS) was 0.89 ± 0.53 µm, which reduced to 0.38 ± 0.24 µm (P < 0.001), and RMS coma of 0.45 ± 0.29 µm improved to 0.20 ± 0.12 µm (P < 0.001). Though there was a marginal reduction from 0.04 ± 0.14 to 0.03 ± 0.07, RMS spherical aberration did not show any statistically significant difference (P = 0.37). RMS secondary astigmatism reduced from 0.17 ± 0.15 µm to 0.08 ± 0.12 µm (P = 0.007), and RMS trefoil reduced to 0.13 ± 0.09 µm from 0.64 ± 0.36 µm (P < 0.001) with SLs and showed statistically significant improvement.

Conclusion:
SLs can be considered an effective option that corrects a significant amount of HOAs and enhances visual performances in PMD eyes.
Distortion-Product Otoacoustic Emission of Cochlear Hair Cells in Pediatric Patients Presenting with Various Perinatal Morbidities
Authors: Mahanta Bhaswati , Bhattacharjee Abhinandan 
Published: June 2024

Background:
Hearing plays a substantial role in the growth of intellect- as well as language-related abilities in children. Congenital hearing loss leads to deficiency and defects in the growth of various abilities such as speech leading to emotional distress. The aim of our study was to detect cochlear hair cell damage in various perinatal morbidities as measured from distortion-product otoacoustic emission (DPOAE) in the pediatric age group.

Materials and Methods:
A 1-year prospective observational study was conducted on 65 children comprising 28 pediatric and 37 neonatal patients attending a tertiary care hospital.

Results:
Among 65 children, 25% of patients having perinatal risk factors failed the OAE test. The majority of neonates passed the OAE test (97.3%) as compared to the pediatric age group (60.7%). The most common risk factor associated with OAE “fail” was neonatal jaundice (100%), followed by low birth weight (35%) and respiratory distress (36%). We found no relation of “fail” OAE test with the Apgar scale (4–6). The mean signal–noise ratio (SNR) variable was highest in the frequency range of 4 and 6 kHz in neonates with statistically significant values for the frequency band of 2, 4, and 6 kHz. The above findings confirmed that the OAE recordings observed in the group of children were reliable.

Conclusion:
The SNR variable of DPOAE is an effective and reliable screening tool at particular frequencies. Emphasis on hearing screening using OAE should be prioritized in cases of neonatal jaundice and respiratory distress and also for patients in the age group from >1 month to 12 years.
Hearing Aid Fitting and Fine-tuning Strategies Implemented by Certified Audiologists in India
Authors: Sigdel Surakshya , Srividya A. , Babu Praveena 
Published: June 2024

Background:
Management of hearing-impaired individuals using hearing aids requires expertise in fitting formulas, compression methods, frequency adjustments, microphone directionality, noise reduction algorithms, and feedback management. There are abundant online resources/guidelines for programming and fine-tuning hearing aids. The fitting strategies for hearing aids can differ among professionals based on their expertise and convenience.

Aims and Objectives:
The survey study aimed to gain comprehension of the methods used by audiologists practicing in Indian subcontinent in choosing, fitting, and tuning hearing aids for adults with hearing impairment.

Materials and Methods:
A web-based survey with a 25-item questionnaire was carried out among audiologists nationwide, addressing topics such as hearing aid selection and fitting techniques. Among the audiologists practicing in India, 77 audiologists from various workplaces across India responded to the survey. The data gathered were then subjected to descriptive analysis.

Results:
The study showed that the selection of hearing aids depended on the extent of hearing loss and the main listening needs of the person. Audiologists generally used manufacturers’ initial fit and their expertise to adjust different signal processing features and considered patient feedback for additional adjustments. Most audiologists use only pure-tone audiometry for the initial evaluation of hearing abilities.

Conclusion:
The findings of the research underscore the absence of standardized procedures for audiologists in the fitting of hearing aids, considering the numerous signal-processing approaches present in contemporary hearing technology. Despite exponential advancements in hearing aid technology, there remains a scarcity of concise and accessible information that would enable audiologists to utilize such sophisticated technologies during fitting and tuning effectively.
Impact of full coverage of population with Long-Lasting Insecticidal Nets (LLINs) on malaria vector density in Gadchiroli district of Maharashtra, India
Authors: Kumar Gaurav , Ojha VP 
Published: June 2024

Background & objectives:
Long-lasting insecticidal nets (LLINs) are a major weapon in the fight against malaria. But protection of each family member is not possible with current distribution system with 80% coverage. Therefore, we hypothesized that the distribution of LLIN to every member of a household will be more effective at reducing vector density and ultimately malaria in endemic areas like district Gadchiroli of Maharashtra, India.

Methods:
The three sub centers Kulbhati, Pannemara and Yerkad of Murumgaon Primary Health Center of Gadchiroli district were selected for the study based on malaria incidence and LLIN distribution. Pre-structured questionnaires were filled to know the distribution and use of LLIN as baseline, thereafter additional LLINs were distributed in selected villages for 100% coverage of population. Entomological surveys were undertaken to know the impact of LLIN on vector mosquito density.

Results:
A total of 250 houses were surveyed in these villages and questionnaires were filled regarding bednet distribution and their use. 507 LLIN were distributed in study villages (population 1270) of Murumgaon PHC. In four selected villages, additional 409 LLIN were distributed for 100% coverage of population with bed nets. Man hour density of vector mosquito in human dwellings in the experimental villages was significantly reduced, 0–19 in comparison to control (0–66). In cattle sheds, MHD of An. culicifacies was observed to be 1-243 in experimental villages vis-à-vis 1-179 in control villages. During exit trap collection of mosquitoes, ~94 % mosquitoes were deterred from blood feeding.

Interpretation & conclusion:
In this study there was a significant impact of insecticide-treated nets on vector mosquito density in human dwellings. Thus, 100% coverage of human populations with LLINs may be an important tool in controlling malaria situation in endemic areas like Gadchiroli.
Indicators sandflies and environment associated to spatial landscaping change in Chocó Biosphere Reserve UNESCO
Authors: Enríquez Sandra , Arrivillaga-Henríquez Jazzmín , Duque Paul , Herrera Vanessa , Vaca Franklin , Sánchez Marco , Roldán Mateo , Ron-Garrido Lenin , Molina C Alfonso 
Published: June 2024

Background & objectives:
Sandflies are vector insects associated with terrestrial forest ecosystems; in the Ecuadorian Andes, they participate in the transmission of human cutaneous leishmaniasis. This geographical area represents an opportunity to evaluate the role of sandflies as bioindicators of the degree of intervention of tropical humid forest ecosystems (THF) associated with changes in the ecology of the local landscape.

Methods:
CDC-light traps were used for collecting adult sandflies in February 2020 in a humid tropical forest within the Chocó Biosphere Reserve. All species were identified using morphological keys. Analysis data about abundance, richness, species accumulation, diversity index, species composition communities, species sex proportion, spatial sandflies environmental, Renyi’s Diversity Profile were performed to compare six spatial habitats in Mashpi locality, Ecuador.

Results:
Sandflies were collected (n-1435); the main species are represented by Trichophoromyia reburra, Nyssomyia trapidoi, Psathyromyia aclydifera, Psychodopygus panamensis and Lutzomyia hartmanni. Only Th. reburra is associated with not intervened forest, while the other three species are associated with intervened forest within Mashpi in the Choco Biosphere Reserve. The secondary forest has major sandflies’ richness, while the primary forest exhibits major abundance.

Interpretation & conclusion:

Th. reburra is a sandfly restricted to the Andean Forest and is a bioindicator of the high environmental health quality of the forest, while Ny. trapidoi and Pa. aclydifera are bioindicators of environmental disturbances in the forest. Additionally, Ps. panamensis, Lu. hartmanni and Ny. trapidoi are bioindicators of human impact and the risk of leishmaniasis.