bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proximity based trust‐advisor using encounters for mobile societies: Analysis of four filters
Authors: Kumar Udayan , Thakur Gautam , Helmy Ahmed 
Published: December 2010

AbstractMany interactions between network users rely on trust, which is becoming particularly important given the security breaches in the Internet today. These problems are further exacerbated by the dynamics in wireless mobile networks. In this paper, we address the issue of trust advisory and its establishment in mobile networks, with application to ad hoc networks, including delay tolerant (DTNs). We utilize encounters in mobile societies in novel ways, noticing that mobility provides opportunities to build proximity, location, and similarity based trust. Four new trust advisor filters are introduced – including encounter frequency, duration, behavior vectors, and behavior matrices. The filters are evaluated over an extensive set of real‐world traces collected from a major university. Two sets of statistical analyses are performed; the first examines the underlying encounter relationships in mobile societies, and the second evaluates DTN routing in mobile peer‐to‐peer networks using trust and selfishness models. We find that for the analyzed trace, trust filters are stable in terms of growth with time (three filters have close to 90% overlap of users over a period of 9 weeks) and the results produced by different filters are noticeably different. In our analysis for trust and selfishness model, our trust filters largely undo the effect of selfishness on the unreachability in a network. Thus improving the connectivity in a network with selfish nodes. We hope that our initial promising results open the door for further research on proximity‐based trust. Copyright © 2010 John Wiley & Sons, Ltd.
Joint Tx/iterative Rx FDE for broadband direct‐sequence code division multiple access
Authors: Takeda K. , Adachi F. 
Published: December 2010

AbstractDirect‐sequence code division multiple access (DS‐CDMA) is a promising uplink access technology for broadband cellular mobile communication systems. In this paper, we propose a joint transmit (Tx)/iterative receive (Rx) frequency‐domain equalization (FDE) for DS‐CDMA. In the proposed scheme, simple one‐tap FDE at the transmitter and iterative one‐tap FDE at the receiver are jointly performed using the common knowledge of channel state information (CSI). Before transmitting the signal, the transmitter predicts the degree of residual inter‐chip interference (ICI) power after the iterations of Rx FDE to determine the Tx FDE weight while the receiver performs the iterative Rx FDE. In practice, it is almost impossible to share the perfect knowledge of CSI. In this paper, a Gaussian approximation of channel estimation (CE) errors is introduced. We theoretically derive a set of Tx and iterative Rx FDE weights based on the minimum mean square error (MMSE) criterion in the presence of the CE error. We show by computer simulation that the proposed scheme provides better bit error rate (BER) performance than the conventional scheme which uses iterative Rx FDE only (i.e., without Tx FDE) even in the presence of CE error. Copyright © 2010 John Wiley & Sons, Ltd.
On the relay position selection for the diamond network over Nakagami‐m fading channels
Authors: Wang Qing , Fan Pingyi 
Published: December 2010

AbstractThe diamond relay channel, or diamond relay network, is a kind of efficient cooperative network in which the source node cooperates with two neighbors. In this paper, we study the impact on the performance of such a network caused by the relays' position for a general Nakagami‐m fading channel, which extends the previous work for a special Rayleigh fading case. In particular, the symmetric scenario for the two relays is investigated but the channel conditions of the two source‐relay‐destination links may have great difference due to the different values of m for the four Nakagami‐m fading channels. We study how to select the position of the two relays and give clear restrictions of their positions based on the requirement of the throughout improvement and network stability. Finally, we show how to find the optimal position to achieve the largest throughput improvement. The numerical results confirm our analysis and the interesting illustrations show much insight on the cooperative neighbor selections. Copyright © 2010 John Wiley & Sons, Ltd.
Boundary layer effects in rectangular cross‐ply Levy‐type plates using zigzag theory
Authors: Kumari P. , Kapuria S. 
Published: December 2010

AbstractThe boundary layer effect in rectangular laminated plates is studied using an efficient third order zigzag theory. For this purpose, a Levy‐type solution is presented for rectangular plates, with two opposite edges hard‐simply supported. A mixed formulation is employed for the solution. The numerical results are presented for composite and sandwich plates with four boundary conditions. While strong edge effects are observed at the free edges and soft‐simply supported edges, no edge effect appears at the hard‐simply supported edge. The effect of length to thickness ratio and aspect ratio on the boundary layer is investigated. The results are compared with those of the smeared third order theory to ascertain the effect of inclusion of layerwise terms in the displacement approximation of the zigzag theory.
Hybrid complementarity formulations for robotics applications
Authors: Bhalerao K.D. , Crean C. , Anderson K. 
Published: December 2010

AbstractThe focus of this paper is to review hybrid recursive‐complementarity formulations for multibody systems characterized by a large number of bilateral constraints which are frequently encountered in robotics. Here, hybrid implies the use of complementarity contact models with recursive forward dynamics schemes. Such formulations have a common underlying structure which can be applied to multibody systems with a constrained tree‐type topology. These common steps are pointed out. Theoretical formulation is given for systems using three important classes (O(n3), O(n), and O(log (n))) of multibody algorithms. Further, numerical comparison for the efficiency is given for rigid multibody systems. The paper makes recommendations on the choice of hybrid complementarity formulations which would result in the most efficient simulation. The paper further gives a non‐iterative approach to allow the use of explicit higher order integrators for frictionless contacts. The difficulties in extending this approach to allow for frictional contact are also discussed.
Spatial heterogeneity of soil chemical properties at fine scales induced by Haloxylon ammodendron (Chenopodiaceae) plants in a sandy desert
Authors: Li Congjuan , Li Yan , Ma Jian 
Published: December 2010

AbstractSpatial heterogeneity is considered a ubiquitous feature in natural ecosystems. Fertile islands represent a typical example for such heterogeneity in desert ecosystems. The soil pH and salinity also show significant heterogeneity in fertile islands. To investigate the distribution of soil salinity and nutrients around individual shrubs and the major factors influencing their distribution, an experiment was conducted at the scale of the rhizosphere, root system, and individual for Haloxylon ammodendron (C. A. Mey.) Bunge (Chenopodiaceae) shrub in the Gurbantünggüt Desert. Specifically, the heterogeneity of the following soil chemical parameters was evaluated: pH, electrical conductivity (EC), soil organic carbon (SOC), total nitrogen (TN), and available phosphorus (AP). The chemical properties of the shrub stemflow were also evaluated to determine its contribution to the formation of fertile islands and the distribution of soil salinity. The results revealed great variance in the soil pH and EC at the rhizosphere and root system scales, indicating that a single root or root system exerts a great effect on soil pH and salinity. At the individual scale, the content of SOC, TN, and AP was significantly enriched in the layers adhering to the taproot, and this enrichment extended 20–40 cm from the taproot. Conversely, the soil pH and EC were significantly lower from the taproot to 10–25 cm away from the root, indicating that the fertile island is also an island of low alkalinity/salinity. Comparison of the chemical properties of stemflow and bulk precipitation revealed a higher content of chemical elements (except pH and CO32−) in the stemflow, indicating that the fertile island and lower pH and EC in this island were likely formed by the effects of stemflow. Specifically, stemflow brings in water and nutrients, while reducing the salt levels. Overall, the high nutrients and low alkalinity/salinity island created around the taproot favor the growth of the plants.
Brief report: The Identity Style Inventory (ISI‐3) and the Utrecht‐Management of Identity Commitments Scale (U‐MICS): Factor structure, reliability, and convergent validity in French‐speaking university students
Authors: Zimmermann Grégoire , Mahaim Elodie Biermann , Mantzouranis Gregory , Genoud Philippe A. , Crocetti Elisabetta 
Published: December 2010

ABSTRACTThe purpose of this study was to evaluate the factor structure and the reliability of the French versions of the Identity Style Inventory (ISI‐3) and the Utrecht‐Management of Identity Commitments Scale (U‐MICS) in a sample of college students (N = 457, 18–25 years old). Confirmatory factor analyses confirmed the hypothesized three‐factor solution of the ISI‐3 identity styles (i.e. informational, normative, and diffuse‐avoidant styles), the one‐factor solution of the ISI‐3 identity commitment, and the three‐factor structure of the U‐MICS (i.e. commitment, in‐depth exploration, and reconsideration of commitment). Additionally, theoretically consistent and meaningful associations among the ISI‐3, U‐MICS, and Ego Identity Process Questionnaire (EIPQ) confirmed convergent validity. Overall, the results of the present study indicate that the French versions of the ISI‐3 and UMICS are useful instruments for assessing identity styles and processes, and provide additional support to the cross‐cultural validity of these tools.
Clinical Issues—January 2011
Authors: Blanchard Joan 
Published: December 2010

Use of indwelling urinary catheters for perioperative patientsKey words: indwelling urinary catheter, urinary tract infection, Foley catheter.Managing an Acinetobacter baumannii outbreakKey words: Acinetobacter baumannii, opportunistic pathogen, health care‐associated infection, colonization pressure, bloodstream infection.Frequently asked questions about meningitisKey words: bacterial meningitis, viral meningitis, meningococcal infection, pneumococcal polysaccharide vaccine, meningococcal polysaccharide vaccine, pneumococcal conjugate vaccine.Implementing droplet precautionsKey words: droplet precautions, personal protective equipment.
Clinical Update: Suspension Trauma
Authors: Pasquier Mathieu , Yersin Bertrand , Vallotton Laurent , Carron Pierre-Nicolas 
Published: December 2010

Objective Suspension trauma refers to the pathophysiologic syndrome that occurs when a victim is suspended motionless in a vertical position for an extended period of time. This can occur in sports that use a harness system as well as in various occupational activities including work on high wires or helicopter rescue operations. We reviewed the scientific evidence published to date in order to improve the prevention and treatment of suspension trauma. Methods Medline, PreMedline, the Cochrane Library, and Google Scholar were searched for relevant information about suspension trauma. Results Published data describing the pathophysiology of and the therapeutic approach to suspension trauma are sparse and consist mainly of case reports and a limited number of human experimental prospective studies. The pathophysiology of suspension trauma is related to hypovolemia induced by reduced venous return and by vagal stimulation. It is also influenced by the type of harness used. Chest harnesses may induce severe cardiorespiratory repercussions and have the lowest motionless suspension tolerance. Symptoms of suspension trauma include presyncope and can lead to a loss of consciousness. Conclusions Sports enthusiasts and workers who use a body harness system should never act alone and should not use a simple chest harness. If a victim shows symptoms of presyncope or is unconscious, he should be released from suspension as soon as is safely possible. There is no clear evidence to support the idea that the return to the horizontal position may contribute to the potential risk of rescue death.
Keynote: A renaissance for the point mutation: from legacy data to semantic web service
Authors: Baker Christopher 
Published: December 2010

AbstractExperiments that construct or discover protein point-mutations and investigate their functional consequences represent one of the cornerstones of biomedical investigation. And yet, despite the importance of these annotations, the interpretation and reuse of knowledge about their impacts remains a formidable task. This is due to a number of reasons including (i) the publishing of salient mutation impact descriptions in unstructured text, (ii) the existence of numerous boutique databases of mutation information which can have many years of latency, and (iii) errors within manually populated mutation databases. In recent years the mining of mutations from scientific documents has emerged as a promising research theme resulting in automated methods for mutation extraction and denovo database creation. While such methods have shown good performance, this alone does not suffice in seamlessly integrating mutation annotations to other biological datatypes.In this talk I demonstrate the challenges and innovations that have resulted in the deployment of semantic services that supply text-extracted mutation impact annotations on demand. These include; mutation grounding algorithms linking extracted mutations to the correct position on wild type protein sequences, the grounding of mutated protein properties to GO Molecular Function, rule based extraction of mutation impacts and impact direction, conceptualization and population of mutation impact ontology, graphical composition of SPARQL queries using mutation specific metadata, visualization of mutation impact annotations on protein structures, dynamic annotation of PubMed abstracts containing mutations mentions using the Semantic Assistant framework , and lastly SADI web service deployment facilitating queries that leverage mutation impact annotations integrated with multiple semantic web services, namely queries that select for mutations that impact specific protein properties, mutations that impact specific metabolic or signaling pathways, drugs that target mutated proteins, and literature describing mutations on proteins with a given nsSNP.
Angiotensin receptor blockers and angiogenesis: clinical and experimental evidence
Authors: Willis Lauren M. , El-Remessy Azza B. , Somanath Payaningal R. , Deremer David L. , Fagan Susan C. 
Published: December 2010

Angiotensin II type 1 receptor antagonists [ARBs (angiotensin receptor blockers)] are indicated for BP (blood pressure)-lowering, renal protection and cardioprotection in patients unable to tolerate ACEIs (angiotensin-converting enzyme inhibitors). A recent meta-analysis revealed an association between ARBs and tumour development, possibly due to enhancement of angiogenesis. However, published evidence is conflicting on the effects of ARBs on angiogenesis or the expansion of the existing vascular network. ARBs have been shown to exert primarily anti-angiogenic effects in basic science studies of cancer, retinopathy, peripheral artery disease and some models of cardiovascular disease. In animal and cellular models of myocardial infarction and stroke, however, ARB administration has been associated with robust increases in vascular density and improved recovery. The aim of the present review is to examine the angiogenic effects of ARBs in animal and cellular models of relevant disease states, including proposed molecular mechanisms of action of ARBs and the clinical consequences of ARB use.
Ancient watercourses and biogeography of the Sahara explain the peopling of the desert
Authors: Drake Nick A. , Blench Roger M. , Armitage Simon J. , Bristow Charlie S. , White Kevin H. 
Published: December 2010

Evidence increasingly suggests that sub-Saharan Africa is at the center of human evolution and understanding routes of dispersal “out of Africa” is thus becoming increasingly important. The Sahara Desert is considered by many to be an obstacle to these dispersals and a Nile corridor route has been proposed to cross it. Here we provide evidence that the Sahara was not an effective barrier and indicate how both animals and humans populated it during past humid phases. Analysis of the zoogeography of the Sahara shows that more animals crossed via this route than used the Nile corridor. Furthermore, many of these species are aquatic. This dispersal was possible because during the Holocene humid period the region contained a series of linked lakes, rivers, and inland deltas comprising a large interlinked waterway, channeling water and animals into and across the Sahara, thus facilitating these dispersals. This system was last active in the early Holocene when many species appear to have occupied the entire Sahara. However, species that require deep water did not reach northern regions because of weak hydrological connections. Human dispersals were influenced by this distribution; Nilo-Saharan speakers hunting aquatic fauna with barbed bone points occupied the southern Sahara, while people hunting Savannah fauna with the bow and arrow spread southward. The dating of lacustrine sediments show that the “green Sahara” also existed during the last interglacial (∼125 ka) and provided green corridors that could have formed dispersal routes at a likely time for the migration of modern humans out of Africa.
Reaction mechanism of
Drosophila
cryptochrome
Authors: Ozturk Nuri , Selby Christopher P. , Annayev Yunus , Zhong Dongping , Sancar Aziz 
Published: December 2010

Cryptochrome (CRY) is a blue-light sensitive flavoprotein that functions as the primary circadian photoreceptor in
Drosophila melanogaster
. The mechanism by which it transmits the light signal to the core clock circuitry is not known. We conducted in vitro studies on the light-induced conformational change in CRY and its effect on protein–protein interaction and performed in vivo analysis of the lifetime of the signaling state of the protein to gain some insight into the mechanism of phototransduction. We find that exposure of CRY to blue light induces a conformation similar to that of the constitutively active CRY mutant with a C-terminal deletion (CRYΔ). This light-induced conformation has a half-life of ∼15 min in the dark at 25 °C and is characterized by increased affinity to Jetlag E3 ligase. In vivo analysis reveals that in the
Drosophila
S2 cell line, the signaling state induced by a millisecond light exposure has a half-life of 27 min in the dark at 0 °C during which period it is susceptible to degradation by the ubiquitin-proteasome system. These findings lead to a plausible model for circadian photoreception/phototransduction in
Drosophila
.
DiNAMIC: a method to identify recurrent DNA copy number aberrations in tumors
Authors: Walter Vonn , Nobel Andrew B. , Wright Fred A. 
Published: December 2010

Abstract
Motivation: DNA copy number gains and losses are commonly found in tumor tissue, and some of these aberrations play a role in tumor genesis and development. Although high resolution DNA copy number data can be obtained using array-based techniques, no single method is widely used to distinguish between recurrent and sporadic copy number aberrations.
Results: Here we introduce Discovering Copy Number Aberrations Manifested In Cancer (DiNAMIC), a novel method for assessing the statistical significance of recurrent copy number aberrations. In contrast to competing procedures, the testing procedure underlying DiNAMIC is carefully motivated, and employs a novel cyclic permutation scheme. Extensive simulation studies show that DiNAMIC controls false positive discoveries in a variety of realistic scenarios. We use DiNAMIC to analyze two publicly available tumor datasets, and our results show that DiNAMIC detects multiple loci that have biological relevance.
Availability: Source code implemented in R, as well as text files containing examples and sample datasets are available at http://www.bios.unc.edu/research/genomic_software/DiNAMIC.
Contact: vwalter@email.unc.edu; fwright@bios.unc.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
TCP Transcription Factors Link the Regulation of Genes Encoding Mitochondrial Proteins with the Circadian Clock in Arabidopsis thaliana
Authors: Giraud Estelle , Ng Sophia , Carrie Chris , Duncan Owen , Low Jasmine , Lee Chun Pong , Van Aken Olivier , Millar A. Harvey , Murcha Monika , Whelan James 
Published: December 2010

Abstract
Diurnal regulation of transcripts encoding proteins located in mitochondria, plastids, and peroxisomes is important for adaptation of organelle biogenesis and metabolism to meet cellular requirements. We show this regulation is related to diurnal changes in promoter activities and the presence of specific cis-acting regulatory elements in the proximal promoter region [TGGGC(C/T)], previously defined as site II elements, and leads to diurnal changes in organelle protein abundances. These site II elements can act both as activators or repressors of transcription, depending on the night/day period and on the number and arrangement of site II elements in the promoter tested. These elements bind to the TCP family of transcriptions factors in Arabidopsis thaliana, which nearly all display distinct diurnal patterns of cycling transcript abundance. TCP2, TCP3, TCP11, and TCP15 were found to interact with different components of the core circadian clock in both yeast two-hybrid and direct protein–protein interaction assays, and tcp11 and tcp15 mutant plants showed altered transcript profiles for a number of core clock components, including LATE ELONGATED HYPOCOTYL1 and PSEUDO RESPONSE REGULATOR5. Thus, site II elements in the promoter regions of genes encoding mitochondrial, plastid, and peroxisomal proteins provide a direct mechanism for the coordination of expression for genes involved in a variety of organellar functions, including energy metabolism, with the time-of-day specific needs of the organism.