bluuebunny/crossref_metadata_2025_split huggingface dataset:
948-P: Glycemic and CGM Outcomes Are Nearly Independent of the Frequency of User Engagement with the Bionic Pancreas during 13 Weeks of Use in Adults and Children with Type 1 Diabetes
Authors: DAMIANO EDWARD , SELAGAMSETTY RAJENDRANATH , BRANDT RACHEL , RUSSELL STEVEN J. 
Published: June 2024

It is well established that glycemic and continuous glucose monitoring (CGM) outcomes improve with increasing user engagement for both therapeutic devices (insulin pumps and pens) and diagnostic devices (CGMs, flash-glucose monitors, and blood-glucose monitors) used in the management of type 1 diabetes (T1D). Unlike any other insulin-delivery device, the iLet Bionic Pancreas (BP) determines and delivers 100% of all therapeutic insulin. Given this degree of autonomy, we hypothesized that glycemic and CGM outcomes obtained by the BP might be independent of the frequency of user engagement. To that end, data about user interactions with the BP were captured on the BP during the Bionic Pancreas Pivotal Trial (BPPT), and analyzed retrospectively. The average frequency of meal announcements initiated by each participant using the BP, and the average frequency of swipe gestures to unlock the lock screen of the BP, were analyzed and taken as proxies for user engagement with the device. Among 219 adults with T1D who used the BP for 13 weeks during the BPPT, the mean CGM glucose level was 156 ± 12 mg/dl. The average number of meal announcements and swipes to unlock the screen were 2.8/day and 9.9/day, respectively. The slope and intercept of the linear correlation between the mean CGM glucose level and the average number of daily swipes to unlock the screen were -0.08 and 157 mg/dl, respectively. The R2 correlation coefficient was 0.00. Similarly, the slope and intercept of the linear correlation between the mean CGM glucose level and the average number of daily meal announcements were -0.27 and 163 mg/dl, respectively, with an R2 of 0.06. Similar results to these are obtained when using 13-week HbA1c as an outcome. Unlike other therapeutic and diagnostic devices used in T1D management, glucose control achieved by the BP is nearly independent of the frequency of user engagement in terms of the metrics studied here.

Disclosure
E. Damiano: Board Member; Beta Bionics, Inc. Employee; Beta Bionics, Inc. Stock/Shareholder; Beta Bionics, Inc. R. Selagamsetty: Employee; Beta Bionics, Inc. Stock/Shareholder; Beta Bionics, Inc. R. Brandt: Employee; Beta Bionics, Inc. S.J. Russell: Employee; Beta Bionics, Inc. Stock/Shareholder; Beta Bionics, Inc. Other Relationship; Beta Bionics, Inc. Consultant; Beta Bionics, Inc. Research Support; Beta Bionics, Inc. Consultant; Novo Nordisk. Research Support; Novo Nordisk. Other Relationship; Novo Nordisk.
953-P: Changes in Time in Range (TIR) among Youth with Type 1 Diabetes (T1D) Initiating Different Automated Insulin Delivery (AID) Systems
Authors: GERA SONIA , REARSON ANDREW , BAKER GREY , DOUVAS JULIA L. , ALICEA-TRELLES NICOLE , GALLOP ROBERT J. , MEIGHAN SEEMA , MARKS BRYNN E. 
Published: June 2024

Introduction & Objective: Glycemic outcomes in youth with T1D have not been compared between the two most commonly used AID systems in the United States, Insulet Omnipod 5 (OP5) and Tandem Control IQ (CIQ). Our aim is to perform the first head-to-head analysis of changes in TIR in youth initiating AID systems to further support clinical counseling and decision making.
Methods: This single center, retrospective chart review included youth &lt; 21 years who were prescribed OP5 or CIQ between 2022-2023. AID start dates, pump data, 14-day baseline and 90-day continuous glucose monitor data were obtained from proprietary cloud-based software. A multiple linear regression model assessed for differences in 90-day time in range (TIR) according to AID system initiated.
Results: Among 470 youth, 228 (48.5%) started OP5 and 242 (51.4%) initiated CIQ. OP5 users were more likely to identify as female (57.5% vs 47.1%, p=0.03) and non-Hispanic Black (15.4% vs 4.5%, p=&lt;0.01). OP5 users had a shorter TID duration (1.7 [IQR 0.7, 4.4] vs. 5.9 [IQR 2.9, 5.9], p=&lt;0.01) and were more likely to have transitioned to AID from multiple daily injections (76.8% vs 19%, p&lt;0.01). Baseline TIR was similar between groups (OP5 51.0% [IQR 36.3, 67.4] vs CIQ 52.9% [IQR 39.3, 66.3], p=0.74). There was no difference in AID active time (OP5 89.6% vs CIQ 87.4%, p=0.10) or user-initiated boluses per day (OP5 5.0 vs CIQ 5.3, p=0.21). 90-day TIR increased in both groups (p&lt;0.001), rising by 11.9%-points (95% CI [10.3,13.4]) in OP5 users and 9.9%-points (95% CI[8.4,11.5]) in CIQ users. After adjusting for sex, race/ethnicity, T1D duration and prior regimen, improvements in 90-day TIR did not differ between AID systems (p=0.11).
Conclusion: Improvements in 90-day TIR following AID initiation among youth with T1D are significant and do not differ between commonly prescribed systems. Further studies are required to understand patient-related factors that may lead to differential success with a particular AID system.

Disclosure
S. Gera: None. A. Rearson: None. G. Baker: None. J.L. Douvas: None. N. Alicea-Trelles: None. R.J. Gallop: None. S. Meighan: Speaker's Bureau; Dexcom, Inc. B.E. Marks: Research Support; Tandem Diabetes Care, Inc., Dexcom, Inc., Medtronic, Digostics. Advisory Panel; International Society for Pediatric and Adolescent Diabetes, American Diabetes Association, T1D Exchange. Board Member; Juvenile Diabetes Research Foundation (JDRF).
958-P: High User Satisfaction and Ease-of-Use Scores with Six Months Use of the Tandem t:connect Mobile Application
Authors: ASSADI KIMIA , MANNING MICHELLE L. , PINSKER JORDAN E. , MESSER LAUREL H. 
Published: June 2024

Objective: People with diabetes who use the t:slim X2 with Control-IQ technology (CIQ, Tandem Diabetes Care) in the United States also have the option to use the smartphone app (t:connect mobile), which includes the ability to bolus from the app, and continuously upload data to the cloud. This study explores user satisfaction and perceptions of ease of use (EOU) of the smartphone app.
Methods: People with type 1 and type 2 diabetes using CIQ completed surveys on satisfaction and perceived EOU of the app after 6 months of use. Data collection occurred June 2023 through November 2023.
Results: 3,687 individuals completed surveys at 6 months (54% female, 88% type 1 diabetes, 25% previous MDI users). Of 2,695 who responded to the satisfaction metric, 79.6% were either satisfied or very satisfied with the smartphone app. Of the 2,433 who responded to the EOU metric, 83.6% considered the app “easy” or “very easy” to use. Individuals who use the bolus feature of the app had comparably higher satisfaction and EOU percentages (84% satisfied and 88% EOU) compared to individuals who did not use the bolus feature (69% satisfied, 71% EOU)
Conclusion: Users new to Tandem report high satisfaction and EOU for the t:connect mobile smartphone app. The consistently positive perceptions indicates that the CIQ system with the mobile app hold general appeal, potentially assuaging pump hesitancy fears in people not yet using a pump.

Disclosure
K. Assadi: Employee; Tandem Diabetes Care, Inc. Stock/Shareholder; Tandem Diabetes Care, Inc. M.L. Manning: Employee; Tandem Diabetes Care, Inc. J.E. Pinsker: Employee; Tandem Diabetes Care, Inc. L.H. Messer: Employee; Tandem Diabetes Care, Inc.

Funding
Tandem Diabetes Care
970-P: Safety and Glucose Control with "Do It Yourself Android Artificial Pancreas System" Using Freestyle Libre Sensor + MiaoMiao in Patients with Type 1 Diabetes
Authors: DANTAS MARIA EDUARDA P. , MESSIAS LARYSSA D.S. , VENTURA GABRIELLA L. , DE LOURDES MACHADO MARIA , SOUTO DÉBORA L. , DANTAS JOANA R. , SOARES THIAGO M. , SANTOS EDSON P. , OLIVEIRA TÁSSIA , ZAJDENVERG LENITA , RODACKI MELANIE 
Published: June 2024

Introduction & Objective: Do it yourself (DIY) Android Artificial Pancreas Systems (AAPS) integrate insulin infusion and glucose sensors at lower cost than commercial systems. Freestyle Libre™ 1 + MiaoMiao™ + insulin pump has been poorly studied for this purpose. This study aims to evaluate the effectiveness and safety of this system in patients with type 1 diabetes (T1D).
Methods: This is an observational study performed in Brazil. Patients were recruited through social media. Data was collected remotely with a questionnaire (AirTable). Non pregnant individuals with more than 3 years of T1D who used DIY AAPS were included. Continuous glucose monitoring data, quality of life (QOL) through DQOL-Brazil instrument and hemoglobin A1c (A1c) prior and after treatment were accessed.
Results: 69 patients were included, with mean age and disease duration of 36.4 ± 13.2 and 20.9 ±12.1 years, respectively. Among them, 60.9% had higher education. Mean time in range, hypoglycemia &lt; 70 mg/dL, hypoglycemia &lt; 54 mg/dL, hyperglycemia &gt; 180 mg/dL, hyperglycemia &gt; 250 mg/dL and glucose coefficient variability were 78.5% ± 16.6, 4.1% ± 3.4, 1.3% ± 1.8, 16.1% ± 11.9, 4.1% ± 5.6 and 46.3% ±16.2, respectively. Mean A1c before and after treatment were 8.9 ± 11.6 and 6.4% ± 0.7, respectively. 75.5% of patients had A1c &lt;7%. The frequency of reported severe hypoglycemia in the past year and weekly hypoglycemia were 0.4 (±1.0) and 3.3 (± 2.2), respectively. 79.2% of the responders were very/moderately satisfied with their treatment and 64.2% were very/ moderately satisfied with time spent to manage T1D.
Conclusion: DIY AAPS with Freestyle Libre™ 1 + MiaoMiao™ seems safe and well accepted by patients with T1D in Brazil. Most users had A1c &lt; 7% and significantly improved A1c after initiation, but percentage of time in hypoglycemia and glucose CV are still above target, which might be related to algorithm limitations, the system components or lack of proper patient education.

Disclosure
M.P. Dantas: None. L.D. Messias: None. G.L. Ventura: None. M. Machado: None. D.L. Souto: None. J.R. Dantas: None. T.M. Soares: None. E.P. Santos: None. T. Oliveira: None. L. Zajdenverg: None. M. Rodacki: None.
993-P: Exploring CGM Adherence and Glycemic Metrics in People with Diabetes—Real-World Data from Dexcom Users
Authors: HICKS CHRISTIAN , CRAWFORD MARGARET A. , SINGH HARSIMRAN 
Published: June 2024

We previously identified that greater frequency and duration of gaps in CGM wear period were associated with lower time in range (TIR) in adults with T2D. The current study explored impact of CGM wear period on glycemic metrics by diabetes type in adult and pediatric users.
Random samples of 1000 Dexcom G6 users each from June 2022 were pulled for T2D adults (≥18 years), T1D adults (≥18), and T1D pediatrics (&lt;18). T2D pediatric cohort was excluded due to data insufficiency. Gaps in CGM wear period &gt;3 days defined as extended gaps (EGs) were observed over 3 months. Comparisons were made between users with and without ≥1 EG. Regression models estimated the effects of EGs and cohorts on CGM metrics.
Overall, sample reported a high median [IQR] CGM wear time (96% [86, 99]). EGs were present in only 31% of users. T2 adults had 1.8 (95% CI: 1.5 - 2.2) times greater odds than T1 adults and 2.3 (1.9 - 2.8) times greater odds than T1 pediatrics to have EGs (Table). After adjusting for cohorts, presence of EGs was significantly associated with 9% (8 - 11) lower TIR and 0.4% (0.3 - 0.5) greater GMI. Significant associations were also identified with time above range, mean glucose, and coefficient of variation.
Odds of EGs varied by diabetes type and age. T2 adults had the greatest odds of EGs, which were associated with less optimal CGM metrics. These results suggest that uninterrupted CGM access may result in beneficial glycemic outcomes.

Disclosure
C. Hicks: Employee; Dexcom, Inc. M.A. Crawford: Employee; Dexcom, Inc. H. Singh: Employee; Dexcom, Inc.
Pengaruh Variasi Komposisi Minyak Almond, Lidah Buaya dan Aqua pada Sediaan Lotion Bayi dengan Penambahan Minyak Ketumbar (Corriander Oil)
Authors: Dewi Eryantri Chintya , Hidayati Nur 
Published: June 2024

Kulit bayi dan anak rentan terhadap trauma dan infeksi, sehingga membutuhkan perawatan khusus. Oleh karena itu, penambahan aditif berbasis bahan kimia, harus dapat direduksi. Produk yang umumnya digunakan untuk anak dan bayi adalah lotion. Aditif bahan kimia yang umum digunakan adalah penetration enhancers, yang ditambahkan agar meningkatkan penyerapan lotion melalui kulit. Pada penelitian, dilakukan formulasi lotion berbahan dasar alami, tanpa menggunakan aditif kimia. Komposisi dasar yang dipilih adalah berupa ini minyak almond, lidah buaya dan aqua pada sediaan lotion rambut bayi dengan menggunakan penambahan minyak ketumbar (Coriander oil). Pengaruh perbedaan komposisi bahan tersebut, akan dievaluasi berdasarkan uji organoleptik, uji daya sebar, uji homogenitas, uji daya lekat, dan uji pH. Pada uji organoleptik dihasilkan warna putih, dengan tekstur semi cair dan aroma ketumbar. Untuk uji homogenitas diperoleh hasil yang bervariasi. Didapatkan pH yang sudah sesuai dengan SNI. Daya lekat dari lotion bervariasi, yaitu 11 s.d 17 detik. Daya sebar berkisar antara 4,7 cm – 7 cm. Penambahan minyak almond yang terlalu banyak menyebabkan minyak almond sulit menyatu dengan bahan lain, sehingga perlu penambahan aqua yang lebih banyak agar mendapatkan tekstur lotion yang diinginkan.
Інтерполяційна задача Ньютона в класі мероморфних функцій із швидкозростаючими
вузлами
Authors: Онисько В. З. , Шепарович І. Б. 
Published: June 2024

Нехай (λk) — послiдовнiсть рiзних комплексних чисел така, що

і

У роботi отримано асимптотичну оцiнку мероморфної функцiї, поданої у виглядi ряду
рацiональних дробiв:

де (ak) — послiдовнiсть комплексних чисел така, що

Також доведено, що мероморфну функцiю, що має нулi в точках {λk, k ∈ ℕ} та полюси в
точках {uλk, k ∈ ℕ}, для якої зовнi кругiв U (uλk, σ) := {|z - uλk| ≤ σ} (σ > 0)
виконується:

можна зобразити у виглядi вказаного функцiонального ряду, де
Saúde, desenvolvimento humano e regional
Authors: Bazzanella Sandro Luiz 
Published: June 2024

Alguns aspectos do presente artigo foram apresentados no colóquio no I Congresso de promoção à Saúde realizado no dia 16 de Outubro de 2014, na Universidade do Contestado, Campus de Mafra – Santa Catarina. Participaram do colóquio o professor Dr. Markus Nahas da Universidade Federal de Santa Catarina, na condição de mediador do debate e, a professora Drª. Ana Maria Girotti Sperandio da Faculdade de Jaguariúna – São Paulo. A reflexão proposta se divide em três momentos reflexivos. Num primeiro momento, argumenta em torno da importância e das dificuldades das definições conceituais implicadas no termo desenvolvimento em suas diversas acepções e adjetivações. Num segundo momento, o artigo procura demonstrar de que forma a vida em sua dimensão meramente biológica se tornou o objeto por excelência da razão política, administrativa e jurídica do Estado na modernidade e, de forma mais intensa na contemporaneidade. Na terceira seção do artigo, a reflexão procura articular os conceitos de Estado, desenvolvimento e saúde, apontando para o fato de que o desenvolvimento de uma determinada região, senão do país depende do grau de vitalidade de suas instituições públicas, de seus atores privados e, da sociedade civil organizada.
AHP Applied in Choosing a Power System for Autonomous Vehicles
Authors: Nogueira Edison Cesar de Faria , Santos Genildo Nonato , Xavier Marcelle Caruzo , Dantas Gabriel Rodrigo de Souza , Flach Elton 
Published: June 2024

Objective: In the present work, a literature review was carried out with the objective of listing and analyzing commercially viable options for battery technologies for application in Automatic Guided Vehicles (AGV) or Autonomous Vehicles in the industrial segment.

Theoretical Framework: The literature review made it possible to gather basic information about the concepts that support the study, as well as the data that will be analyzed.

Method: For the selection of works and synthesis of information, the PRISMA bibliometric review protocol was used. The research was carried out on the Periódicos Capes platform, finding and analyzing 23 articles. The AHP methodology was used to choose the best alternative using criteria based on “usability” and sustainability.

Results and Discussion: From the results of the analyzes carried out, it was possible to verify that the most efficient energy storage technology was Lithium-ion technology, given its moderate performance in all factors considered.

Implications of the research: AVGs have their application within industrial environments and the use of batteries is essential for the mobility of these equipment. Storing electric energy in such a way as to optimize such mobility and also to have a minimum impact on the environment and the health of workers is a matter of high relevance for companies concerned with environmental, social and governance issues (ESG).

Originality: As far as we know, there are very few comparative papers published on battery technology that have application in AVG. None of them makes a broad comparison, like the one made in the present study, both in terms of commercial, social and sustainability.
The Psychological Motivations Left by Exile in the Souls of Knight Poets
Authors: Al-Mobaideen Nadeem Yousef Mohammed 
Published: June 2024

Objective: The study focused on the key components that analyzed the psychological reasons behind the continuing impact of gossip on the renowned knights.

Theoretical Framework: A brief presentation was required where the researcher discusses pre-Islamic poetry and then provides knowledge about the psychological motivation to help readers grasp the book's objective.

Method: We examined psychoanalytic theories to comprehend the specific psychological condition of the knightly poet while analyzing his poetry. We proceeded to explore the essence of the study to elucidate the underlying psychological causes, which were the surroundings and emotions.

Results and Discussion: Pre-Islamic poetry remains a shining beacon and a pure source of knowledge. It is considered a secret of the Arab genius in the pre-Islamic era. We have reached a stage of ancient heritage that concealed within its folds the secret of intellectual brilliance, which distinguished the pre -Islamic poet, in addition to eloquence and linguistic eloquence.

Research Implications: Research suggests that knightly poets require psychological reasons to enhance their creativity.

Originality/Value: The text discusses how knightly poets use poetic verses to depict psychological expressions related to dandruff and gray hair among women. It explores the motives behind these expressions in the poets' works.
The Role of Cybersecurity in Enhancing the Effectiveness of Law Against Cybercrimes
Authors: Al-Amaireh Monther Abed-Alrazzaq Musleh 
Published: June 2024

Objective: This study aims to understand the nature of cybercrimes and the challenges faced by legal authorities in combating them.

Theoretical Framework: The progress in information and communication technology is not limited to the positive aspects related to technology and infrastructure development. It has also revealed a negative side with serious implications for the state and its sovereignty. This negative aspect has eroded privacy and greatly encouraged the proliferation of cybercrimes, posing a threat to international security and peace. The negative aspect is manifested in the phenomenon of cyberattacks that now threaten a nation's security and its citizens, necessitating measures to mitigate these threats.

Method: in this study, the descriptive analytical approach was followed by analyzing the texts in Jordanian law and describing each case dealt with in relation to the role of cyber security in enhancing the effectiveness of criminal law against cybercrimes.

Results and Discussion: The role of cybersecurity in addressing cybercrimes is of significant importance in ensuring the safety of information and preserving digital security for individuals and institutions, Jordanian legislation has imposed deterrent laws to combat cybercrimes, including the Electronic Crimes Law and the Cybersecurity Law.

Research Implications: The study also reached a number of recommendations, including the need to develop a clear legal framework to combat cybercrime, strengthen cybersecurity in all fields, train its employees and raise their efficiency.

Originality/Value: The significance of this study arises from the increasing severity of cyber threats and electronic crimes worldwide, which have become a serious threat to individuals, organizations, and nations. As a result, enhancing the effectiveness of criminal law in combating these electronic crimes has become an urgent necessity.
At The Pivot Point of Cultural Education Management, Teaching, and Artistic Practice
Authors: Mayo Sherry 
Published: June 2024

Objective: The objective of this paper is to examine the paradigmatic shifts in teaching methodologies, educational, cultural, and artistic practices that occurred during the pandemic and post-pandemic with the aim to provide implications of what will be next for these roles during the recovery phase.

Theoretical Framework: The Higher Education system of distributing instruction was disrupted by the COVID pandemic and both crisis and opportunity resulted from these new modalities of learning. New pedagogical approaches were developed, and this paper looks particularly at art education, art making, and cultural management looking at innovation and issues of digital equity. This pivoting caused a paradigmatic shift in the way participants experienced art, culture, and learning with both pros and cons. (Dodson, J. 2021). What is the role of educational and cultural managers, and artists during this next phase of recovery (Leonard, N. 2020)?

Method: The primary source of data was empirical observation and exchange with faculty, staff, and students. This is not a research study, but a historical paper based on an educator’s practice. From this perspective, the logic for constructing knowledge is based on research in the literature supporting themes from the field of art education and those proposed by the author.

Results and Discussion: The results revealed in the research were derived by the author from both their empirical observations and experience and their research in the literature. In the discussion section, these results are contextualized considering the theoretical framework, highlighting the implications and relationships identified. Possible limitations of the research include that no one really knows what the future may hold.

Research Implications: The practical and theoretical implications of this research are discussed, providing insights into how the results can be applied or influence practices in the field of art education. These implications could encompass artistic practice and cultural management as well.

Originality/Value: This study contributes to the literature by connecting art education, artistic practice, and cultural management and showing their value as well as projecting the future of emerging technologies and what essential roles art practitioners play in this new world. The relevance and value of this research are evidenced by the implications for education, digital literacy, and equity. I also point the way towards workforce development for arts and technology-related jobs. The paper places a priority on high-end digital skills for every citizen.