bluuebunny/crossref_metadata_2025_split huggingface dataset:
If health organisations and staff engage in research, does healthcare improve? Strengthening the evidence base through systematic reviews
Authors: Boaz Annette , Goodenough Belinda , Hanney Stephen , Soper Bryony 
Published: May 2024

Abstract

Background
There is a widely held assumption that the engagement of clinicians and healthcare organisations in research improves healthcare performance at various levels. Previous reviews found small numbers of studies that suggest an association between the engagement of individuals and healthcare organisations in research, and improvements in healthcare performance. The current study sought to provide an update.
Methods
The team updated an existing published systematic review, and addressed the question: Does research engagement (by clinicians and organisations) improve healthcare performance? The search covered the period January 1, 2012 to March 2024, in two phases. First, the formal updated search ran from January 1, 2012 to May 31, 2020, in any healthcare setting or country and focused on English language publications. In this phase two searches identified 66,901 records. Second, a further check of key journals and citations to identified papers ran from May 2020 to March 2024. In total, 168 papers progressed to full-text appraisal; 62 were identified for inclusion in the update.
Results
Fifty-eight of the 62 papers report positive results, of which 48 are purely positive and 10 positive/mixed meaning that there are some negative elements (i.e., aspects where there is a lack of healthcare improvement) in their findings. In the updated review, the literature is still dominated by papers from the US (35/62) and is mostly drawn from the Global North. The papers cover a range of clinical fields but with considerably more on cancer than any other field.
Conclusions
The updated review collates a substantial pool of studies, especially when combined with our first review, which are largely positive in terms of the impact of research engagement on processes of care and patient outcomes. Of the potential engagement mechanisms, the review highlights the important role played by research networks. The review also identifies various papers which consider how far there is a “dose effect” from differing amounts of research engagement. Additional lessons come from analyses of equity issues and negative papers. This review provides further evidence of the contribution played by systems level research investments such as research networks on processes of care and patient outcomes.
Exploring the Impact of Supplier Relationship Management Practices on Operational Efficiency and Customer Satisfaction in Italian Restaurants
Authors: Mitchell Eleanor 
Published: May 2024

Abstract

Purpose
This study explores the impact of supplier relationship management practices on operational efficiency and customer satisfaction in Italian restaurants.
Design/Methodology/Approach:
Utilizing a qualitative research approach, data was collected through interviews and surveys from 200 participants across various Italian restaurants.
Findings:
The analysis revealed strong correlations between supplier relationship management practices and other operational variables, emphasizing the interconnectedness of management strategies. Effective supplier relationship management not only enhances supply chain efficiency but also influences ingredient sourcing, menu diversity, and technological integration.
Research Limitations/Implications:
While technological advancements were found to contribute to operational efficiency, their direct impact on customer satisfaction was limited. The study underscores the multifaceted nature of customer satisfaction determinants, suggesting the need for a balanced approach combining technology with personalized service. Continuous improvement opportunities were identified, providing insights for restaurant operators to refine strategies and better align with customer expectations.
Practical Implications:
While this study offers valuable insights into Italian restaurant management, it has limitations, including its qualitative nature and reliance on self-reported data.
Social Implications:
Nonetheless, the findings contribute to the existing body of knowledge and offer practical implications for restaurant operators aiming to enhance operational efficiency and customer satisfaction.
Originality/Value:
By recognizing the interconnectedness of management practices and adopting customer-centric approaches, Italian restaurants can position themselves for sustained success in a competitive culinary landscape.
The Future of TCR-like Antibodies in Diagnosis and Potential Application
Targets
Authors: Liu Huaqiang , Dass Sylvia Annabel , Balakrishnan Venugopal , Nordin Fazlina , Tye Gee Jun 
Published: May 2024

Abstract::
The human leukocyte antigen (HLA, also known as the major
histocompatibility complex or MHC) system, is responsible for immune monitoring of
the intracellular proteome of all nucleated cells. The presentation of antigen peptides
separates malignant or infected cells from their healthy counterparts and forms
aberrant cells tagged as the foundation for identification. Therefore, peptide-MHC
molecules can give potential diagnostic targets for cancer or infection. TCR-like
antibodies recognize specific peptides that bind to MHC molecules, allowing them to
target Such inaccessible cytoplasmic or nuclear tumors or virus-associated antigens. It
binds to MHC, presenting peptides found on the surface of target cells. These
antibodies have shown promising clinical applications in diagnosing and imaging
cancer and infected cells. This review presents the current situation of TCR-like
antibodies and its prospects for application in the field of intracellular antigen
diagnostics. It also lists the potential application targets of TCR, like antibodies in
various disease diagnoses, providing valuable information for developing diagnostic
reagents and selecting targets in the future.
Preparation of a Novel Multifunctional Cationic Liposome Drug-carrying System and
its Functional Study on Lung Cancer
Authors: Kong Yi , Xu Li , Cao Jun 
Published: May 2024

Background:
Low-dose chemotherapy is a promising treatment strategy that may be improved by
controlled delivery.

Objective:
This study aimed to design polyethylene glycol-stabilized bilayer-decorated magnetic Cationic Liposomes
(CLs) as a drug delivery system for integrated functional studies of lung cancer cell therapy and imaging.

Methos:
A novel multifunctional folic acid targeting magnetic CLs docetaxel drug-loading system (FA-CLs-Fe-
DOC) was prepared and tested for its physical properties, encapsulation rate and drug release performance. The
feasibility of FA-CLs-Fe-DOC ability to inhibit tumor cells and act as an MRI contrast agent was investigated in
vitro, and the target recognition and therapeutic ability of FA-CLs-Fe-DOC was studied in vivo.

Results:
FA-CLs-Fe-DOC had a particle size of 221.54 ± 6.42 nm and a potential of 28.64 ± 3.56 mv, with superparamagnetic
properties and better stability. The encapsulation rate was 95.36 ± 1.63%, and the drug loading
capacity was 9.52 ± 0.22%, which possessed the drug slow-release performance and low cytotoxicity and could
effectively inhibit the proliferation of lung cancer cells, promoting apoptosis of lung cancer cells. MRI showed
that it had the function of tracking and localization of lung cancer cells. In vivo experiments confirmed the targeted
recognition property and therapeutic function of lung cancer cells.

Conclusion:
In this study, we successfully prepared an FA-CLs-Fe-DOC capable of specifically targeting lung
cancer cells with integrated functions of efficient lung cancer cell killing and imaging localization. This targeted
drug packaging technology may provide a new strategy for the design of integrated carriers for targeted cancer
therapy and imaging.
Secondary Metabolites from the Mangrove-derived Fungus Trichoderma sp.
Authors: Zi Guangrong , Shi Ying , Hong Kui , Liu Ling 
Published: May 2024

Background::
Secondary metabolites from the mangrove-derived fungi have great potential
to produce natural products with novel structures and significant biological activities.

Objective::
The objective of this study was to isolate and identify the secondary metabolites from the
mangrove-derived fungus Trichoderma sp. WHUF0342, and evaluate their antibacterial activities.

Methods::
The compounds were isolated and purified by silica gel column chromatography, Sephadex
LH-20 gel chromatography, and semi-preparative high-performance liquid chromatography
(HPLC). Their structures were elucidated by comparing the NMR and MS spectroscopic data with
those of literature. The antibacterial activity were evaluated by modified broth microdilution assay.

Results::
Eight compounds were isolated from the fermented extracts of the fungus Trichoderma sp.
WHUF0342 and identified as chaxine B (1), nafuredin (2), dichlorodiaportin (3), ferulaic acid (4),
bis(2-ethylhexyl) benzene-1,2-dicarboxylate (5), methyl 4-hydroxyphenylacetate (6), 4-
hydroxyphenyl acetate (7), and 4-hydroxyphenylethyl acetate (8). Chaxine B (1) showed antibacterial
activity against the phytopathogenic bacterium Ralstonia solanacearum with a minimum inhibitory
concentration (MIC) value of 16 μg/mL. The antibacterial activity against plant pathogen of compound
1 was reported for the first time in this study.

Conclusion::
This study not only enriched the secondary metabolites of mangrove-derived fungi but
also provided a valuable resource for the prevention of agricultural pathogen infections.
A Multimodal Fusion and Ensemble Approach for Robust Fake News Detection through Deep Learning, Reinforcement Learning, and Using Blockchain to Enhance Security and Authorization
Authors: Kumar Vivek , Satveer  , Ahmad Waseem , Kumar Satendra 
Published: May 2024

Background:
Computer science significantly influences modern culture, especially with
the rapid breakthroughs and technology in social media networking. Social media platforms have
become significant channels for sharing and exchanging daily news and information on many issues
in the current digital environment, which is known for its massive data collection and transmission
capabilities. While there are many benefits to this environment, there are also many false reports and
information that deceive readers and users into believing they are receiving correct information.

Objective:
Nowadays, all users use social media to obtain news content, but sometimes some malicious
users tamper with real news and then spread fake news, which may reduce the reputation of
social media. Therefore, many existing models have been introduced to detect fake news, but these
models are based on traditional machine learning algorithms, such as decision tree (DT), multilayer
perceptron (MLP), random forest (RF), etc. These models Lack of performance, security, and authorization.
Our proposed model can solve existing model problems using reinforcement learning and
blockchain technology.

Methods:
In this research paper, we explain a new way to identify fake news. This new approach,
combined with policy-based heuristic reinforcement learning (PHRL), where the model dynamically
adjusts through iterative learning, is the key innovation and gradually improves classification accuracy.
The same as our smart contract authorization method, which enhances the authenticity of content
posted safely by authorized users and improves the transparency and accountability of information.

Results:
Our model was tested on real-time information collected from various sources with 70%
accuracy and valid authentication.

Conclusion:
Our proposed model produced better results with a Mean Absolute Error (MAE) of
0.0811 and Root Mean Squared Error (RMSE) of 0.2847, both significantly lower values. Our proposed
model performs better than multilayer perceptron (MLP), and random forest (RF).
Análisis psicométrico de dos versiones del Big Five Inventory-15 en estudiantes universitarios chilenos: estructura interna, invarianza de medición y asociación con bienestar subjetivo
Authors: Dominguez-Lara Sergio , Carmona-Halty Marcos , Schulmeyer Marion K. , Valente Sabina N. , Lourenço Abílio A. 
Published: May 2024

El objetivo de esta investigación fue analizar la estructura interna de dos versiones del Big Five Inventory-15 (BFI-15), invarianza de medición y su relación con el bienestar subjetivo en estudiantes universitarios chilenos. Participaron 1011 estudiantes (mujeres = 54.80 %; Medad = 21.55 años; DEedad = 2.11 años). Los resultados indican que la versión peruana del BFI-15 (BFI-15p) tiene indicadores más consistentes con relación a su estructura interna (e.g., cargas factoriales) en comparación a la versión alemana (BFI-15a), así como una estructura invariante entre hombres y mujeres, y una asociación significativa con las dimensiones del bienestar subjetivo. Finalmente, la confiabilidad del constructo y de las puntuaciones alcanzó magnitudes adecuadas. Se concluye que el BFI-15p presenta propiedades psicométricas adecuadas para su uso en universitarios chilenos.
Pelatihan Penelitian Tindakan Kelas dan Penulisan Artikel Ilmiah bagi Guru SD dan SMP
Authors: Pagiling Sadrack Luden , Tembang Yonarlianto , Rahayu Dewi  Puji , Riyana Minuk , Sardiana I Ketut , Purnawan Ni Luh Ramaswati , Siti Ni Wayan 
Published: May 2024

Pengetahuan dan keterampilan guru-guru SD dan SMP yang masih minim dalam melakukan penelitian tindakan kelas (PTK) dan mempublikasikan artikel ilmiah menyebabkan kesulitan untuk mengurus kenaikan pangkat. Oleh karena itu, pengabdian ini bertujuan untuk memberikan pelatihan PTK dan penulisan artikel ilmiah bagi guru-guru SD dan SMP. Metode yang digunakan dalam pengabdian ini yaitu metode pelatihan, diskusi, dan demonstrasi. Pelatihan ini melibatkan 13 guru-guru SD dan SMP yang berada di Kabupaten Merauke, Provinsi Papua Selatan. Tim pelaksana pengabdian ini melakukan evaluasi untuk mengetahui pemahaman guru dengan cara menyebar angket melalui googleform untuk mengetahui pemahaman guru terkait PTK serta teknik penulisan artikel ilmiah yang baik. Hasil pelatihan mendemonstrasikan bahwa 13 guru memiliki pemahaman yang baik terkait dengan pengetahuan PTK dan penulisan artikel melalui pelatihan dan pendampingan dengan skor penilaian di tingkat persetujuan antara 6 dan 7. Selanjutnya, 10 guru berhasil menulis artikel hasil PTK yang selanjutnya didampingi untuk melakukan submit artikel di jurnal nasional. Pelatihan ini disimpulkan berhasil karena mampu memberikan pengetahuan yang berharga bagi guru-guru SD dan SMP dalam melaksanakan PTK dan menulis artikel ilmiah.
Sistema de baixo custo para ensaios em bancada e determinação do máximo torque de protótipos de motores elétricos
Authors: Colaço Fabrício , Baran Eduardo Léo , Rambo Marcos Vinicio Haas 
Published: May 2024

Este projeto visou analisar, compreender e estabelecer uma série de elementos que concernem a um sistema de baixo custo para ensaios em bancada e determinação do máximo torque de protótipos de motores elétricos. Para responder aos requisitivos determinados para sistema destaca-se o uso dos seguintes elementos: Microcontrolador ESP32-Wroon-32 para efetuar o processamento da leitura dos sensores e controle dos atuadores programado usando a plataforma de desenvolvimento Arduino IDE 1.8.19. Display para apresentação dos dados. Aplicativo de celular que se comunica com o sistema microcontrolado, via protocolo Bluetooth low energy (BLE). Para o armazenamento de dados, adotou-se as memórias do tipo SD. O presente trabalho possibilitou a empregabilidade de ferramentas e técnicas modernas que fomentam o controle, a aquisição, o processamento e a apresentação de dados para a análise do usuário.
Pengaruh Metode Aplikasi dan Konsentrasi Gibberellic Acid (GA3) terhadap Fase Pertumbuhan Vegetatif Tanaman Nanas (Ananas comosus [L.] Merr.)
Authors: Maraaini Ajeng , Widyatuti R. A. Diana , Warganegara Hayane Adeline , Karyanto Agus 
Published: May 2024

Increasing the production of pineapple fruit can be done by manipulating the plant using Gibberellic Acid Growth Regulatory Substance (ZPT). The purpose of this study was to determine the effect of GA3 concentration and application method, as well as its interaction in increasing the vegetative growth of pineapple plants. Data collection was carried out in November 2022- February 2023 at a pineapple plantation company in Central Lampung. Treatments were arranged factorial (3x2) using a randomized block design with 3 replications. The first factor was Gibberellin (A) which consisted of three levels, (A1) 0 ppm GA3, (A2) 200 ppm GA3, and (A3) 400 ppm GA3. The second factor is the application method (B) which consists of 2 levels, namely (B1) Application on the top of the leaf (B2) Application on the bottom of the leaf. The observed variables included plant height, stem diameter, number of leaves, D-leaf length, D-leaf width, number of roots, root length, fresh weight of roots, fresh weight of plants. Homogeneity of variance between treatments was tested by Barlett's test and additivity using Tukey's test and then analysis of variance was carried out. Separation of the mean was carried out using the least significant difference test (LSD) at the 5% level. The results showed that 400 ppm GA3 was better than the control in affecting plant fresh weight with a difference of 630,7 g, the treatment of the application method on the leaves was better than the bottom leaf in affecting plant fresh weight with a difference 201,4 g. Treatment with a concentration of 40 ppm using the leaf application method was better than the control treatment. It is suggested to do further research related to the effect of giving GA3 on the generative phase of pineapple plants.Keywords : Gibberellic Acid, application method, pinneaple
Pertumbuhan dan Produksi Tanaman Sawi Pakcoy (Brassica rapa L.) Akibat Dibudidayakan pada Berbagai Komposisi Media Tanam dan Konsentrasi Pupuk Organik Cair dengan Sistem Vertikultur
Authors: Efendy Yessy Pristika , Suhardjono Hadi , Widiwurjani Widiwurjani 
Published: May 2024

Pakcoy (Brassica rapa L.) is one of the important and popular vegetable crops in Indonesia. City development and massive urbanization have resulted in the shrinking of agricultural land in urban areas. Home gardens have great potential if managed optimally and planned. Therefore, the concept of urban farming with the vertical farming method can be a solution. This study aimed to determine the optimal composition of planting media and liquid organic fertilizer (LOF) concentration for the growth and production of pakcoy plants. This study used a completely randomized design (CRD) with two factors. The first factor was the composition of the planting medium, which consisted of three levels: soil, compost, and goat manure with a ratio of 1:1:1, 1:1:2, and 1:2:1. The second factor was the concentration of LOF and urea, which consisted of four levels: 1 gram urea, 2 ml/liter water, 4 ml/liter water, and 6 ml/liter water. The results of the study showed that the combination of planting medium composition and LOF concentration had an effect on all observation parameters. The combination of planting medium composition 1:1:2 and LOF concentration of 4 ml/liter water produced the best results for all observation parameters, namely plant height, number of leaves, total fresh weight, fresh head weight, fresh root weight, and plant dry weight. Key words : Pakcoy mustard, verticulture, media composition, concentration, LOF
Efektivitas Bahan Penyiraman dan Macam Media Tanam terhadap Pertumbuhan Microgreens Tanaman Bunga Matahari (Helianthus annuus L.)
Authors: Rahayu Fita Dwi , Kusumaningrum Nora Augustien , Sulistyono Agus 
Published: May 2024

Microgreens are mini vegetable plants with high nutrition that are managed in a controlled growing environment. Management of microgreens requires sufficient water, nutrients, sunlight, planting media and air. The research aims to obtain the nutrient watering materials and media types for sunflower microgreens' growth. This research was carried out in Sumbang Bojonegoro village in October-December 2021. This research was prepared in a Completely Randomized Design (CRD) consisting of 2 factors, namely 2 levels of nutrient watering material, water (P1) and rice-washing water (P2), while 3 levels of planting media: husk charcoal (M1), sand (M2) and cocopeat (M3). The parameters observed were the percentage of germination, germination rate, number of normal and abnormal sprouts, sprout length, cotyledon width, sprout moisture content, sprout wet weight, and sprout dry weight. The observation data was analyzed used analysis of variance (ANOVA), with a further Least Significant Difference (LSD) test is carried out at a test level of 5%. Phytochemical tests for microgreens include chlorophyll, vitamin C and protein levels. The results showed that applying water and rice-washing water were not significantly different in terms of % germination and germination rate, while cocopeat media was more effective in terms of % germination, number of normal sprouts, % water content, wet weight of microgreens, length of sprouts and width of cotyledons. Highest phytochemical content % chlorophyll 23.60 mg/L (water+sand media); % Vitamin C content 59.40 mg/100g (water + husk charcoal media) and % protein content 3.47% (rice-washing water + sand media). Keywords: Planting media, rice-washing water, microgreens, phytochemical, watering
Food Supply in Bashkortostan during Great Patriotic War: Failures and Violations
Authors: Antoshkin A. V. 
Published: May 2024

This study examines the disruptions in the operations of state trade enterprises and consumer cooperatives in providing food to the population of Bashkortostan during the Great Patriotic War. The article is based on unpublished documents from the National Archives of the Republic of Bashkortostan, as well as materials from periodicals. It is revealed that the weakening of the state’s control functions led to an increase in embezzlement and theft in trade and public catering enterprises. The combination of reduced trade turnover and the rise in abuses within the supply system resulted in severe food shortages. Supply disruptions affected workers, officials, evacuated populations, children, and medical institutions. Various abuses are discussed, including food ration card counterfeiting, different forms of self-supply, and instances of double provisioning. Attention is given to violations in accounting for population groups and inflated supply norms. It is established that combating abuses in the supply system was complicated by the involvement of enterprise leaders, shop workers, accountants, and representatives of auditing bodies in criminal activities. The conclusion is drawn that despite numerous violations, the supply system only minimally provided essential food items to the population of Bashkortostan with interruptions and not in full.