bluuebunny/crossref_metadata_2025_split huggingface dataset:
To conserve African tropical forests, invest in the protection of its most endangered group of monkeys, red colobus
Authors: Linder Joshua M. , Cronin Drew T. , Ting Nelson , Abwe Ekwoge E. , Aghomo Florence , Davenport Tim R. B. , Detwiler Kate M. , Galat Gérard , Galat‐Luong Anh , Hart John A. , Ikemeh Rachel A. , Kivai Stanislaus M. , Koné Inza , Konstant William , Kujirakwinja Deo , Long Barney , Maisels Fiona , McGraw W. Scott , Mittermeier Russell A. , Struhsaker Thomas T. 
Published: April 2024

AbstractForest loss and overhunting are eroding African tropical biodiversity and threatening local human food security, livelihoods, and health. Emblematic of this ecological crisis is Africa's most endangered group of monkeys, the red colobus (genus Piliocolobus). All 17 species, found in forests from Senegal in the west to the Zanzibar archipelago in the east, are threatened with extinction. Red colobus are among the most vulnerable mammals to gun hunting, typically disappearing from heavily hunted forests before most other large‐bodied animals. Despite their conservation status, they are rarely a focus of conservation attention and continue to be understudied. However, red colobus can act as critical barometers of forest health and serve as flagships for catalyzing broader African tropical forest conservation efforts. We offer a plan for conservation of red colobus and their habitats and discuss conservation and policy implications.
Adiposity indicators exhibit depot‐ and sex‐specific associations with multimorbidity onset: A cohort study of the UK Biobank
Authors: Ma Lu , Li Ying , Li Gaixia , Sun Jiajun , Zhang Xueli , Shi Zumin , Yan Yating , Duan Yutian , Wang Jing , Li Zengbin , Zhang Lei 
Published: April 2024

AbstractAimThis study investigated the depot‐ and sex‐specific associations of adiposity indicators with incident multimorbidity and comorbidity pairs.Materials and MethodsWe selected 382 678 adults without multimorbidity (≥2 chronic diseases) at baseline from the UK Biobank. General obesity, abdominal obesity and body fat percentage indices were measured.ResultsCox proportional hazard regression analyses of general obesity indices revealed that for every one‐unit increase in body mass index, the risk of incident multimorbidity increased by 5.2% (95% confidence interval 5.0%‐5.4%). A dose‐response relationship was observed between general obesity degrees and incident multimorbidity. The analysis of abdominal obesity indices showed that for every 0.1 increment in waist‐to‐height ratio and waist‐to‐hip ratio, the risk of incident multimorbidity increased by 42.0% (37.9%‐46.2%) and 27.9% (25.7%‐30.0%), respectively. Central obesity, as defined by waist circumference, contributed to a 23.2% increased risk of incident multimorbidity. Hip circumference and hip‐to‐height ratio had protective effects on multimorbidity onset. Consistent findings were observed for males and females. Body fat percentage elevated 3% (0.2%‐5.9%) and 5.3% (1.1%‐9.7%) risks of incident multimorbidity in all adults and females, respectively. Arm fat percentages elevated 5.3% (0.8%‐9.9%) and 19.4% (11.0%‐28.5%) risks of incident multimorbidity in all adults and males, respectively. The general obesity indices, waist circumference, waist‐to‐height ratio, waist‐to‐hip ratio and central obesity increased the onset of comorbidity pairs, whereas hip circumference and hip‐to‐height ratio decreased the onset of comorbidity pairs. These adiposity indicators mainly affect diabetes mellitus‐related comorbidity onset in males and hypertensive‐related comorbidity onset in females.ConclusionsAdiposity indicators are predictors of multimorbidity and comorbidity pairs and represent a promising approach for intervention.
Evaluation of the hydrating benefits of a cationic hyaluronic acid: From biological evaluation to consumer home use trial
Authors: Blanc Catala Justine , Zanchetta Catherine , François Candice , Chapuis Emilie , Joset Nathalie , Meunier Marie , Loeser Florian , Godbille Shan , Scandolera Amandine , Reynaud Romain , Lefèvre Fabrice 
Published: April 2024

AbstractActive ingredients are often assessed based on physiological measurements, but innovative technologies to measure skin sensations can provide a holistic volunteer assessment of the use of an ingredient. In this paper, the hydrating benefits of a cationic hyaluronic acid (HA) were evaluated alongside clinical biometrics and innovative cognitive measurements to determine how biological benefits correlated with volunteers' feelings and perceptions of hydration. The results demonstrated that cationic HA provides hydrating benefits at the clinical level due to its film‐forming properties. Through the use of innovative behavioural measurement tools, we were able to show that these outcomes are perceived by naïve consumers in real‐life conditions. In addition, the benefits of cationic HA reported by users were in accordance with the mental representation they had related to the use of HA, thus the product achieved complete sensorial embodiment. We can conclude that the combination of clinical evaluations and home use trials consolidates product assessment when seeking to measure consumer satisfaction with proven biological benefits.
AV‐optimized conduction system pacing for treatment of AV dromotropathy: A randomized, cross‐over study
Authors: Zupan Mežnar Anja , Mrak Miha , Mullens Wilfried , Štublar Jernej , Ivanovski Maja , Žižek David 
Published: April 2024

AbstractBackgroundSevere first‐degree atrioventricular (AV) block may produce symptoms similar to heart failure due to AV dyssynchrony, a syndrome termed AV dromotropathy. According to guidelines, it should be considered for permanent pacemaker implantation, yet evidence supporting this treatment is scarce.ObjectivesThis study aimed to determine the impact of AV‐optimized conduction system pacing (CSP) in patients with symptomatic severe first‐degree AV block and echocardiographic signs of AV dyssynchrony.MethodsPatients with symptomatic first‐degree AV block (PR > 250 ms), preserved left ventricular ejection fraction, narrow QRS, and AV dyssynchrony were included in the study. In a single‐blind cross‐over design, patients were randomized to AV sequential CSP or backup VVI pacing with a base rate of 40 bpm. We compared exercise capacity, echocardiographic parameters, and symptom occurrence at the end of 3 months of each period.ResultsFourteen patients completed the study. During the AV‐optimized CSP compared to the backup pacing period, patients achieved a higher workload on exercise test (147.2 ± 50.9 vs. 140.7 ± 55.8 W; p = .032), with a trend towards higher peak VO2 (23.3 ± 7.1 vs. 22.8 ± 7.1 mL/min/kg; p = .224), and higher left ventricular stroke volume (LVSV 74.5 ± 13.8 vs. 66.4 ± 12.5 mL; p < .001). Symptomatic improvement was recorded, with fewer patients reporting general tiredness and 71% of patients preferring the AV‐optimized CSP (p = .008).ConclusionsAV‐optimized CSP could improve symptoms, exercise capacity and LVSV in patients with severe first‐degree AV block.
Effectiveness of interventions to enhance shared decision‐making in wound care: A systematic review
Authors: Clemett Victoria J. , Graham Tanya , Woodward Sue , Grocott Patricia 
Published: April 2024

AbstractAimsTo explore the effectiveness of interventions to enhance patient participation in shared decision‐making in wound care and tissue viability.BackgroundCaring for people living with a wound is complex due to interaction between wound healing, symptoms, psychological wellbeing and treatment effectiveness. To respond to this complexity, there has been recent emphasis on the importance of delivering patient centred wound care and shared decision‐making to personalise health care. However, little is known about the effectiveness of existing interventions to support shared decision‐making in wound care.DesignSystematic review of interventional studies to enhance shared decision‐making in wound care or tissue viability. This was reported following the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA) guidelines 2020.MethodsInterventional primary research studies published in English up to January 2023 were included. Screening, data extraction and quality appraisal were undertaken independently by two authors.Data SourcesMedline, EMBASE, Cochrane Central Register of Controlled Trails (trials database), CINAHL, British Nursing Index (BNI), WorldCat (thesis database), Scopus and registries of ongoing studies (ISRCTN registry and clinicaltrials.gov).Results1063 abstracts were screened, and eight full‐text studies included. Findings indicate, interventions to support shared decision‐making are positively received. Goal or need setting components may assist knowledge transfer between patient and clinician, and could lower short term decisional conflict. However, generally findings within this study had very low certainty due to the inconsistencies in outcomes reported, and the variation and complexity of single and multiple interventions used.ConclusionsFuture research on shared decision‐making interventions in wound care should include the involvement of stakeholders and programme theory to underpin the interventions developed to consider the complexity of interventions.Implications for the profession and patient carePatients setting out their needs or goals and exploring patient questions are important and should be considered in clinical care.RegistrationThe review protocol was prospectively registered (PROSPERO database: CRD42023389820).No Patient or Public ContributionNot applicable as this is a systematic review.
A comparative review of human milk banking and national tissue banking programs
Authors: Herson Marisa , Weaver Gillian 
Published: April 2024

AbstractThis paper explores the legislative and operational commonalities and differences in Medical Products of Human Origin (MPHO) programs, including blood, hematopoietic cells, tissues and reproductive cells and human milk banking. The analysis includes ethical principles in donation and utilization, policies and legislation, public awareness and education, registries, guidelines in donor selection, safety and quality assurance, operational models and funding, infrastructure and human resources and biovigilance and evaluation of outcomes. Unlike other MPHO, the need for donor human milk (DHM) may be greatly reduced, that is, by ensuring optimal support for maternal lactation and breastfeeding. This should not be lost in the drive for wider and improved service provision. Nevertheless, increased overall demand for DHM is expected as a result of forthcoming international recommendations and also its increased use as the first‐choice supplement to a mother's own milk both within and beyond preterm, low‐birthweight and sick infant populations. Insight into current human milk banking highlights differences and gaps in practices that can benefit from further exploration and harmonization. Strong similarities with the ethical and operational principles underpinning donation and processing of the diverse MPHO suggest that legislating human milk banks within similar MPHO frameworks may bring additional safety and facilitate improved product quality. Moreover, that MPHO‐inspired models operating within attainable regulatory requirements may contribute to sustainable human milk banking activity and growth.
Headgear therapy in children with Class II malocclusion and the role of compliance on treatment outcome: A nine‐month randomized controlled trial
Authors: Ghislanzoni Luis Huanca , Kiliaridis Stavros , Antonarakis Gregory S. 
Published: April 2024

AbstractObjectivesTo evaluate three‐dimensional movements of maxillary teeth during headgear treatment in Class II growing children, using digital analytical tools, and to determine the effects of compliance on these movements.Materials and MethodsA 9‐month parallel‐group randomized controlled trial was carried out on 40 children with Class II malocclusion, aged 8‐12 years, half assigned to receive a cervical headgear and half to a no‐treatment group, using block randomization. Subjects in the treatment group were instructed to wear the headgear for 12 hours daily and monitored using an electronic module. After 9 months, the following dental outcomes were measured: first maxillary molar distalisation, rotation, tip and torque, arch depth, and interpremolar and intermolar distances. Caregivers and participants were not blinded to group assignments, but those assessing outcomes were. Linear regression models were used to detect differences between groups and correlation coefficients to find correlations between compliance and dental outcomes.ResultsAll 40 included patients were analysed. A significant difference in molar distalisation was observed between the treatment (1.2 mm) and control groups (−0.2 mm). Arch depth change was also increased to a larger extent in the treatment groups (1.3 mm vs 0.1 mm), as was the interpremolar distance (1.9 mm vs 0.4 mm). In contrast, no significant differences in molar rotation or torque change were observed. With regard to compliance, average compliance was 55%. A significant correlation was found between molar distalisation and compliance in the treatment group.ConclusionsHeadgear therapy has significant effects on molar distalisation, arch depth, and arch width. Compliance has a significant positive effect on molar distalisation.
A cold case of hemolytic disease of the fetus and newborn resolved by genomic sequencing and population studies to define a new antigen in the Rh system
Authors: Wilson Brett , Davison Candice L. , Lopez Genghis H. , Millard Glenda M. , Liew Yew‐Wah , Powley Tanya , Campbell Tamika , Jadhao Sudhir S. , Nagaraj Shivashankar H. , Perry Maree , Roulis Eileen V. , Toombs Maree , Irving David O. , Flower Robert L. , Hyland Catherine A. 
Published: April 2024

AbstractBackgroundWe report an obstetric case involving an RhD‐positive woman who had developed a red blood cell (RBC) antibody that was not detected until after delivery of a newborn, who presented with a positive direct antiglobulin test result. Immunohematology studies suggested that the maternal antibody was directed against a low‐prevalence antigen on the paternal and newborn RBCs.ResultsComprehensive blood group profiling by targeted exome sequencing revealed a novel nonsynonymous single nucleotide variant (SNV) RHCE c.486C>G (GenBank MZ326705) on the RHCE*Ce allele, for both the father and newborn. A subsequent genomic‐based study to profile blood groups in an Indigenous Australian population revealed the same SNV in 2 of 247 individuals. Serology testing showed that the maternal antibody reacted specifically with RBCs from these two individuals.DiscussionThe maternal antibody was directed against a novel antigen in the Rh blood group system arising from an RHCE c.486C>G variant on the RHCE*Ce allele linked to RHD*01. The variant predicts a p.Asn162Lys change on the RhCE protein and has been registered as the 56th antigen in the Rh system, ISBT RH 004063.ConclusionThis antibody was of clinical significance, resulting in a mild to moderate hemolytic disease of the fetus and newborn (HDFN). In the past, the cause of such HDFN cases may have remained unresolved. Genomic sequencing combined with population studies now assists in resolving such cases. Further population studies have potential to inform the need to design population‐specific red cell antibody typing panels for antibody screening in the Australian population.
Evaluation of Composite Structural Materials for Heliostat Cost Reduction
Authors: Tsvankin Daniel , Muller Matthew 
Published: April 2024

Abstract
Structures manufactured from steel comprise up to 40% of a concentrating solar thermal power (CSP) heliostat's cost. Composite structures represent a potential opportunity to reduce this cost. A reference heliostat structural model has been created with a reflector area of 25 m2. The design, constructed of low-carbon steel, provides baseline deflection and stiffness under a 21 m/s operating wind speed. Established roster of suitable metal alternative materials is considered including glass, basalt, and carbon fiber-reinforced polymer (GFRP, BFRP, and CFRP, respectively). Three heliostat components are investigated: the pylon, torque tube, and the purlin–strut assembly. Composite material properties are substituted for those of steel, and the beams are re-sized to match the original steel components’ deflection under given wind loads. Weight and cost changes resulting from this resizing are evaluated. It is found that GFRP and BFRP represent a 3 ×–6 × cost premium for the same operating deflection characteristics as steel across all three investigated component classes; with weight reduction only achieved for the purlin–strut assembly. While CFRP components can achieve approximately 25–75% weight savings depending on the application, this comes with a 9 ×–14 × cost increase over the steel baseline for tube-type structures and roughly 5 × cost increase when replacing c-channel structures. This work does not rule out the possibility of cost savings when the heliostat design and kinematics take advantage of composites' specific properties.
Impacts of Developmental Coordination Disorder on Postural Control Mechanisms in Children and Early Adolescents
Authors: Guetiti Sirine , Cadoret Geneviève , Chénier Félix , Blanchet Mariève 
Published: April 2024

Several studies have demonstrated balance impairments in children with developmental coordination disorder (DCD). However, a recent meta-analysis reports that none of the existing studies investigated the entire construct of balance across the same postural task. It is unclear whether anticipatory postural adjustments before voluntary unperturbed leaning tasks are altered in DCD. Anticipatory postural adjustment’s impact on postural control and limits of stability as well as the contribution of proprioception in these mechanisms are also unknown. This study compared the center of pressure displacements of participants with DCD (n = 30) to typically developing participants (n = 20) (9–12 years old). Standing on an AMTI force plate, participants were asked to lean as far as possible forward, backward, rightward, and leftward in both natural and with eyes closed + foam conditions (eight separated trials). The statistical analysis revealed that the DCD group had larger anticipatory postural adjustments, maximal center of pressure excursion, and greater postural instabilities than the control group. The proprioceptive condition does not systematically influence postural performance in DCD. These deficits are, however, increased in mediolateral directions. These impairments could interfere with children’s performance during daily and physical activities and even negatively impact social inclusion.
Rhizospheric bacteria from the Atacama Desert hyper-arid core: cultured community dynamics and plant growth promotion
Authors: Castro-Severyn Juan , Fortt Jonathan , Sierralta Mariela , Alegria Paola , Donoso Gabriel , Choque Alessandra , Avellaneda Andrea M. , Pardo-Esté Coral , Saavedra Claudia P. , Stoll Alexandra , Remonsellez Francisco 
Published: April 2024

ABSTRACT

The Atacama Desert is the oldest and driest desert on Earth, encompassing great temperature variations, high ultraviolet radiation, drought, and high salinity, making it ideal for studying the limits of life and resistance strategies. It is also known for harboring a great biodiversity of adapted life forms. While desertification is increasing as a result of climate change and human activities, it is necessary to optimize soil and water usage, where stress-resistant crops are possible solutions. As many studies have revealed the great impact of the rhizobiome on plant growth efficiency and resistance to abiotic stress, we set up to explore the rhizospheric soils of
Suaeda foliosa
and
Distichlis spicata
desert plants. By culturing these soils and using 16S rRNA amplicon sequencing, we address community taxonomy composition dynamics, stability through time, and the ability to promote lettuce plant growth. The rhizospheric soil communities were dominated by the families Pseudomonadaceae, Bacillaceae, and Planococcaceae for
S. foliosa
and Porphyromonadaceae and Haloferacaceae for
D. spicata
. Nonetheless, the cultures were completely dominated by the Enterobacteriaceae family (up to 98%). Effectively, lettuce plants supplemented with the cultures showed greater size and biomass accumulation. We identified 12 candidates that could be responsible for these outcomes, of which 5 (
Enterococcus, Pseudomonas, Klebsiella, Paenisporosarcina,
and
Ammoniphilus
) were part of the built co-occurrence network. We aim to contribute to the efforts to characterize the microbial communities as key for the plant’s survival in extreme environments and as a possible source of consortia with plant growth promotion traits aimed at agricultural applications.

IMPORTANCE
The current scenario of climate change and desertification represents a series of incoming challenges for all living organisms. As the human population grows rapidly, so does the rising demand for food and natural resources; thus, it is necessary to make agriculture more efficient by optimizing soil and water usage, thus ensuring future food supplies. Particularly, the Atacama Desert (northern Chile) is considered the most arid place on Earth as a consequence of geological and climatic characteristics, such as the naturally low precipitation patterns and high temperatures, which makes it an ideal place to carry out research that seeks to aid agriculture in future conditions that are predicted to resemble these scenarios. Our main interest lies in utilizing microorganism consortia from plants thriving under extreme conditions, aiming to promote plant growth, improve crops, and render “unsuitable” soils farmable.