bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aortic dissection accompanied by preeclampsia and preterm labor
Authors: Parlakgumus Huriye Ayse , Haydardedeoglu Bulent , Alkan Ozlem 
Published: September 2010

AbstractAortic dissection is a potentially fatal disease rarely encountered in obstetric clinics. A multiparous woman with a prior cesarean delivery was admitted with the complaint of epigastric pain at 33 weeks of gestation. The patient was diagnosed with preeclampsia and preterm labor. An emergent cesarean delivery was performed. Hypertension and epigastric pain could not be controlled after the operation. Computed tomography scan 2 days after the operation revealed aortic dissection, multiple infarct areas in the spleen and liver, and dilations of the intestine and the colon. Ascending aorta replacement followed by massive intestinal resection starting from the ligament of Trietz to the sigmoid colon was performed. Nine hours after the operation the patient had cardiopulmonary arrest. Aortic dissection should be suspected in cases of atypical epigastric pain even if the patient shows signs of preeclampsia and preterm labor.
Influence of previous abortions and new paternity on the risk of hypertension in nulliparous parturients in Ibadan: A cohort study
Authors: Olayemi Oladapo , Strobino Donna , Adedapo Kayode , Aimakhu Christopher , Odukogbe Akin‐tunde , Salako Babatunde 
Published: September 2010

AbstractAim:  This study aims to determine the influence of previous abortions and new paternity on the risk of hypertension in a cohort of nulliparous women.Methods:  A prospective cohort study was conducted with development of hypertension in pregnancy as outcome variable. Explanatory variables were previous abortions and paternity. Univariate analysis was by t‐test, χ2 test and Fisher's exact test where applicable. Logistic regression was utilized for multivariate analysis. Stata was utilized for all the analyses. The level of statistical significance was set as P < 0.05.Results:  Same paternity abortions reduced the risk of hypertension (OR 0.48, 95% CI 0.31–0.73). Previous abortions did not reduce the odds of hypertension in pregnancy (OR 1.25, 95% CI 0.83–1.88). Rural dwelling reduced the odds of developing hypertension in pregnancy (OR 0.54, 95% CI 0.42–0.70).Conclusion:  The result of this study supports the immunological theory of the etiology of hypertension in pregnancy.
Development of the genital ducts and external genitalia in the early human embryo
Authors: Sajjad Yasmin 
Published: September 2010

AbstractThe course of development of the human genital tract is undifferentiated to the 9th week of development. At this time two symmetrical paired ducts known as the mesonephric (MD) and paramesonephric ducts (PMD) are present, which together with the urogenital sinus provide the tissue sources for internal and external genital development. Normal differentiation of the bipotential external genitalia and reproductive ducts are dependent upon the presence or absence of certain hormones. Masculinization of the internal and external genitalia during fetal development depends on the existence of two discrete testicular hormones. Testosterone secreted from Leydig cells induces the differentiation of the mesonephric ducts into the epididymis, vasa deferentia and seminal vesicles, whereas anti‐Müllerian hormone (AMH) produced by Sertoli cells induces the regression of the paramesonephric ducts. The absence of AMH action in early fetal life results in the formation of the fallopian tubes, uterus and upper third of the vagina. In some target tissues, testosterone is converted to dihydrotestosterone, which is responsible for the masculinization of the urogenital sinus and external genitalia.
Evidence for oligomerization between GABAB receptors and GIRK channels containing the GIRK1 and GIRK3 subunits
Authors: Ciruela Francisco , Fernández‐Dueñas Víctor , Sahlholm Kristoffer , Fernández‐Alacid Laura , Nicolau Joel C. , Watanabe Masahiko , Luján Rafael 
Published: September 2010

AbstractThe stimulation of inhibitory neurotransmitter receptors, such as γ‐aminobutyric acid type B (GABAB) receptors, activates G protein‐gated inwardly‐rectifying K+ (GIRK) channels, which influence membrane excitability. There is now evidence suggesting that G protein‐coupled receptors and G protein‐gated inwardly‐rectifying K+ [GIRK/family 3 of inwardly‐rectifying K+ (Kir3)] channels do not diffuse freely within the plasma membrane, but instead there are direct protein–protein interactions between them. Here, we used bioluminescence resonance energy transfer, co‐immunoprecipitation, confocal and electron microscopy techniques to investigate the oligomerization of GABAB receptors with GIRK channels containing the GIRK3 subunit, whose contribution to functional channels is still unresolved. Co‐expression of GABAB receptors and GIRK channels in human embryonic kidney‐293 cells in combination with co‐immunoprecipitation experiments established that the metabotropic receptor forms stable complexes with GIRK channels. Using bioluminescence resonance energy transfer, we have shown that, in living cells under physiological conditions, GABAB receptors interact directly with GIRK1/GIRK3 heterotetramers. In addition, we have provided evidence that the receptor–effector complexes are also found in vivo and identified that the cerebellar granule cells are one neuron population where the interaction probably takes place. Altogether, our data show that signalling complexes containing GABAB receptors and GIRK channels are formed shortly after biosynthesis, probably in the endoplasmic reticulum and/or endoplasmic reticulum/Golgi apparatus complex, suggesting that this might be a general feature of receptor–effector ion channel signal transduction and supporting a channel‐forming role for the GIRK3 subunit.
Neuronal mechanism of mirror movements caused by dysfunction of the motor cortex
Authors: Tsuboi Fumiharu , Nishimura Yukio , Yoshino‐Saito Kimika , Isa Tadashi 
Published: September 2010

AbstractMirror movements (MMs) are often observed in hemiplegic patients after stroke, and are supposed to reflect some aspects of their recovery process. Therefore, understanding the neuronal mechanism of MMs is important, but from the currently available evidence in human case studies, the mechanism of MMs has not been clearly understood. Here we found that in monkeys, after reversible inactivation of the right primary motor cortex (M1) by microinjection of muscimol, MMs were induced in the right hand during voluntary grasping with the left hand, which were partially affected by the injection. Using this animal model, we investigated the origin of MMs after dysfunction of the M1. We found the MMs thus induced were completely abolished by additional blockade of the left M1. Electromyogram (EMG) activities in some homonymous muscle pairs in bilateral hands were co‐activated. Detailed analysis of EMG activities suggested that the enhanced activation of the left M1, which led to MMs in the right hand, was not directly driven by the activity of the right M1, whose activity was likely to be affected by the injection. Rather, the present finding has suggested that common drive of bilateral M1 from higher‐order structures and reduction in commissural inhibition from the affected side concomitantly enhanced the activity of the cortico‐motoneuronal pathway of the intact side, and led to the MMs.
An immunohistochemical investigation of canine idiopathic granulomatous scleritis
Authors: Day M. J. , Mould J. R. B. , Carter W. J. 
Published: September 2010

AbstractThe clinical, histopathologic and immunohistochemical findings in three dogs with granulomatous scleritis are reported. The lesions of granulomatous scleritis were characterized by vasculitis, collagenolysis, granulomatous inflammation and perivascular lymphoplasmacytic aggregation. There was evidence of vascular immune complex deposition, and the inflammatory aggregates contained T lymphocytes, IgG plasma cells and macrophages expressing class II molecules of the major histocompatibility complex (MHC). There was no evidence for an infectious etiology in any case, and one of the dogs subsequently developed cutaneous vascular disease consistent with a systemic immune‐mediated disorder. Canine granulomatous scleritis has an immunopathogenesis likely involving primary type IV hypersensitivity, with a probable underlying type III involvement.
Back in Contention? The Conservatives' Electoral Prospects
Authors: CURTICE JOHN 
Published: September 2010

This article assesses whether the Conservatives are likely to be serious contenders for power at the next British general election. First it assesses how well the party will have to do to ‘win’ the election. Second, it considers whether the record of the polls since 2005 suggests the party is capable of securing the necessary support. Third, the article assesses whether the ideological mood of the electorate has moved closer to the Conservatives since 2005. Finally it considers whether the image of the party has improved.The Conservatives are likely to have to outpoll Labour by a considerable margin to become the largest party but their record in opinion polls suggests they could achieve this. The ideological mood of the electorate has moved closer to the party, while David Cameron is a relatively popular leader. But the party has still not fully restored its reputation for economic competence.
FIRST PERSON PLURAL: SELF‐UNITY AND SELF‐MULTIPLICITY IN THEOLOGY'S DIALOGUE WITH PSYCHOLOGY
Authors: Turner Léon P. 
Published: September 2010

Abstract.In contradistinction to the contemporary human sciences, recent theological accounts of the individual‐in‐relation continue to defend the concept of the singular continuous self. Consequently, theological anthropology and the human sciences seem to offer widely divergent accounts of the sense of self‐fragmentation that many believe pervades the modern world. There has been little constructive interdisciplinary conversation in this area. In this essay I address the damaging implications of this oversight and establish the necessary conditions for future dialogue. I have three primary objectives. First, I show how the notion of personal continuity acquires philosophical theological significance through its close association with the concept of personal particularity. Second, through a discussion of contemporary accounts of self‐multiplicity, I clarify the extent of theological anthropology's disagreement with the human sciences. Third, I draw upon narrative accounts of identity to suggest an alternative means of understanding the experiential continuity of personhood that maintains the tension between self‐plurality, unity, and particularity and thereby reconnects philosophical theological concerns with human‐scientific analyses of the human condition. Narrative approaches to personhood are ideally suited to this purpose, and, I suggest, offer an intriguing solution to understanding and resolving the problem of self‐fragmentation that has caused recent theological anthropology so much consternation.
ALTRUISM: TOWARD A PSYCHOBIOSPIRITUAL CONCEPTUALIZATION
Authors: Morrison Nancy K. , Severino Sally K. 
Published: September 2010

Abstract.Altruism, defined here as a regard for or devotion to the interest of others with whom we are interrelated, is pitted against two other dispositions in human beings: nepotism and egoism. We propose that to become fully human is to become more altruistic. We describe how altruism is mediated by our physiology, is expressed in our psychological development, is evolving in our social institutions, and becomes the moral communities that enforce our sense of right and wrong. A change in any one of these influences changes our disposition—changes who we are and what we do—potentially making altruism more possible in the world.
SPACE AND TIME FROM A NEO‐WHITEHEADIAN PERSPECTIVE
Authors: Bracken Joseph A. 
Published: September 2010

Abstract.Russell Stannard distinguishes between objective time as measured in theoretical physics and subjective time, or time as experienced by human beings in normal consciousness. Because objective time, or four‐dimensional space‐time for the physicist, does not change but exists all at once, Stannard argues that this is presumably how God views time from eternity which is beyond time. We human beings are limited to experiencing the moments of time successively and thus cannot know the future as already existing in the same way that God does. I argue that Stannard is basically correct in his theological assumptions about God's understanding of time but that his explanation would be more persuasive within the context of a neo‐Whiteheadian metaphysics. The key points in that metaphysics are (1) that creation is contained within the structured field of activity proper to the three divine persons of the Christian doctrine of the Trinity and (2) that the spontaneous decisions of creatures are continually ordered and reordered into an ever‐expanding totality already known in its fullness by the divine persons.
THE “DEATH OF THE EGO” IN EAST‐MEETS‐WEST SPIRITUALITY: DIVERSE VIEWS FROM PROMINENT AUTHORS
Authors: Rindfleish Jennifer 
Published: September 2010

Abstract.Eastern religions, such as Hinduism and Buddhism, have traditionally held to the view that in order for an individual to fully benefit from their practice it was important to lessen or eliminate one's individual desires. Such practice was sometimes referred to as the “death of the ego” in order to emphasize its importance. However, the relatively recent popularity of East‐meets‐West spirituality in Western consumer cultures tends to emphasize the acceptance and transformation of one's ego rather than its death. This essay discusses sociological changes that have shaped and contributed to the popularity of East‐meets‐West spirituality in Western culture that in turn have brought about a modification of the principle of ego death. The views of six Western authors and practitioners of East‐meets‐West spirituality on the importance of the principle of ego death are compared and contrasted. Theories related to the management of self‐identity in consumer society can partly explain the modification of traditional Eastern religious practices, such as ego death, in order that they become relevant and appealing to a society that increasingly reifies the concept of the self. The implication is that the excision of the concept of ego death from the practice of East‐meets‐West spirituality may affect its efficacy.
THE FALSE PROMISE OF QUANTUM MECHANICS
Authors: Sansbury Timothy 
Published: September 2010

Abstract.The causal indeterminacy suggested by quantum mechanics has led to its being the centerpiece of several proposals for divine action that does not contradict natural laws. However, even if the theoretical concerns about the reality of causal indeterminacy are ignored, quantum‐level divine action fails to resolve the problem of ongoing, responsive divine activity. This is because most quantum‐level actions require a significant period of time in order to reach macroscopic levels whether via chaotic amplification or complete divine control of quantum events. Therefore, quantum‐level divine action either requires divine foreknowledge of purportedly free or random events or imposes such limitations on divine actions that they become late, potentially impotent, and confused. I argue that the theological problem of divine action remains; even at its most promising, quantum mechanics offers insufficient resolution. This failure suggests a reexamination of the assumptions that God is temporal and lacks foreknowledge of future contingencies.
SOUTH DAKOTA AND ABORTION: A LOCAL STORY ABOUT HOW RELIGION, MEDICAL SCIENCE, AND CULTURE MEET
Authors: Pederson Ann Milliken 
Published: September 2010

Abstract.Telling the tale about South Dakota's recent legislative ban on nearly all abortions gets messy, complicated, and dirty. There are no innocent subjects and no simple plot lines. The story reveals other stories underneath and over the top of the others. Stories counter stories, revealing who is in the know and who does the telling. To “tell the old, old story,” as the song goes, is not as simple as it may seem. Religion and medical science are caught in the politics and cultural wars about abortion.
EVOLUTION AND SUBJECTIVITY
Authors: Kiblinger William P. 
Published: September 2010

Abstract.Evolutionary theory is becoming an all‐encompassing form of explanation in many branches of philosophy. However, emergence theory uses the concept of self‐organization to support yet alter traditional evolutionary explanation. Biologist Stuart Kauffman suggests that the new science will need to tell stories, not simply as a heuristic device but as part of its fundamental task. This claim is reminiscent of C. S. Peirce's criticism of the doctrine of necessity. Peirce's suggestions reference Hegel, and this essay draws out this Hegelian background, addressing the question of subjectivity and issuing some Hegelian reminders so that such evolutionary and emergent theories will consider the implication of this research program on philosophy of mind. The primary focus is on two post‐Kantian, neo‐Hegelian thinkers in contemporary philosophy who deal with this problem: John McDowell and Robert Brandom.
THE CONSEQUENCES OF METAPHYSICS: OR, CAN CHARLES PEIRCE'S CONTINUITY THEORY MODEL STUART KAUFFMAN'S BIOLOGY?
Authors: Bugbee John 
Published: September 2010

Abstract.At the heart of the most radical proposals in Stuart Kauffman's Investigations is his attempt to show that we find in evolutionary biology some configuration spaces—the sets of possible developments for any given system—that (unlike those in traditional physics of Newtonian, relativistic, and quantum stripes) cannot be completely described in advance. We bring Charles Peirce's work on the philosophy of continuity to bear on the problem and discover, first, that Kauffman's arguments do not succeed; second, that Peirce's metaphysics provide new and sounder arguments for the same propositions; third, that Peirce's rigorous but nonstandard treatment of mathematical continuity shows great promise for modeling the unpredictability and growth we find in evolutionary biology; fourth, that it also strengthens a development only hinted at by biologists thus far—the inevitable involvement of the observer's mind in constituting the objects of science. We close with a logical argument for the surprising relevance of metaphysical hypotheses in the natural sciences and with suggestions for future work that will connect these questions to what Kauffman terms the “narrative stance” in biology.
PEIRCEAN APPROACHES TO EMERGENT SYSTEMS IN COGNITIVE SCIENCE AND RELIGION
Authors: Graves Mark 
Published: September 2010

Abstract.Cognitive science and religion provides perspectives on human cognition and spirituality. Emergent systems theory captures the subatomic, physical, biological, psychological, cultural, and transcendent relationships that constitute the human person. C. S. Peirce's metaphysical categories and existential graphs enrich traditional cognitive science modeling tools to capture emergent phenomena. From this richer perspective, one can reinterpret the traditional doctrine of soul as form of the body in terms of information as the constellation of constitutive relationships that enables real possibility.
THE WESTERN ROOTS OF AVATARIC EVOLUTIONISM IN COLONIAL INDIA
Authors: Brown C. Mackenzie 
Published: September 2010

Abstract.British colonialism and Orientalist scholarship on India were key factors affecting the initial Hindu responses to modern science and technology in the nineteenth century. One response was the elaboration of avataric evolutionism—the idea that ancient myths of Vishnu's ten incarnations anticipated Darwinian evolution. This idea quickly became intertwined with political and nationalist concerns and cannot be fully understood in a purely theological context. These concerns were reflected in scriptural interpretation, especially in what may be termed the scientific exegesis of the Vedas and Puranas. Such scientific exegesis of scripture appealed to Keshub Chunder Sen, the leading figure of the Brahmo Samaj in the second half of the nineteenth century. Keshub was apparently the first Indian to develop the notion of avataric evolutionism, in the context of his “New Dispensation,” a synthesis of all religious traditions (in particular Hinduism and Christianity) and modern science. His pronouncement of avataric evolutionism in 1882, however, was not the first proposal of the idea. I conclude with an examination of the Western roots of this idea, specifically in the writings of Helena Petrovna Blavatsky.
CHARLES LYELL, UNIFORMITARIANISM, AND INTERPRETIVE PRINCIPLES
Authors: Anderson Owen 
Published: September 2010

Abstract.I examine the development of Charles Lyell's principle of uniformity and its influence on the development of modern geology and biology and argue that distinguishing between philosophical starting points and empirical findings is essential for clarity in the discussion between science and religion. First, I explore Lyell's arguments against catastrophism and how these were both empirically and religiously motivated. I then consider how David Hume's empiricism, theory of causation, and rejection of miracles influenced Lyell. Using these insights, Lyell formulated his principle of uniformity, which he believed was based on current empirical findings, and rejected explanatory hypotheses that used the biblical Flood or other catastrophist accounts as violations of uniform causation and introductions of theological concepts into empirical science. I next examine the influence of Lyell's principle on Charles Darwin. Although Lyell opposed Darwinism for most of his life, Darwin relied heavily on Lyell, as is evidenced by references throughout The Origin of Species. I contend that the most important aspect of Lyell's principle for Darwin is that it makes natural evil (the struggle for survival) a process that has always been occurring rather than something introduced after the Fall as recorded in Genesis. Finally, I discuss the role that uniformity plays for Lyell, Darwin, and modern science as an interpretive principle rather than as an inference from empirical data, and I conclude by noting that keeping the distinction in mind between interpretive principles and empirical findings will help clarify debates between science and religion.