bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preoperative smoking and robot-assisted radical cystectomy outcomes & complications in multicenter KORARC database
Authors: Choi Joongwon , Lee Jooyoung , Hwang Yu Been , Jeong Byong Chang , Lee Sangchul , Ku Ja Hyeon , Nam Jong Kil , Kim Wansuk , Lee Ji Youl , Hong Sung Hoo , Rha Koon Ho , Han Woong Kyu , Ham Won Sik , Kang Sung Gu , Kang Seok Ho , Oh Jong Jin , Lee Young Goo , Kwon Tae Gyun , Kim Tae-Hwan , Jeon Seung Hyun , Lee Sang Hyub , Park Sung Yul , Yoon Young Eun , Lee Yong Seong 
Published: May 2024

AbstractTo investigate the influence of preoperative smoking history on the survival outcomes and complications in a cohort from a large multicenter database. Many patients who undergo radical cystectomy (RC) have a history of smoking; however, the direct association between preoperative smoking history and survival outcomes and complications in patients with muscle-invasive bladder cancer (MIBC) who undergo robot-assisted radical cystectomy (RARC) remains unexplored. We conducted a retrospective analysis using data from 749 patients in the Korean Robot-Assisted Radical Cystectomy Study Group (KORARC) database, with an average follow-up duration of 30.8 months. The cohort was divided into two groups: smokers (n = 351) and non-smokers (n = 398). Propensity score matching was employed to address differences in sample size and baseline demographics between the two groups (n = 274, each). Comparative analyses included assessments of oncological outcomes and complications. After matching, smoking did not significantly affect the overall complication rate (p = 0.121). Preoperative smoking did not significantly increase the occurrence of complications based on complication type (p = 0.322), nor did it increase the readmission rate (p = 0.076). There were no perioperative death in either group. Furthermore, preoperative smoking history showed no significant impact on overall survival (OS) [hazard ratio (HR) = 0.87, interquartile range (IQR): 0.54–1.42; p = 0.589] and recurrence-free survival (RFS) (HR = 1.12, IQR: 0.83–1.53; p = 0.458) following RARC for MIBC. The extent of preoperative smoking (≤ 10, 10–30, and ≥ 30 pack-years) had no significant influence on OS and RFS in any of the categories (all p > 0.05). Preoperative smoking history did not significantly affect OS, RFS, or complications in patients with MIBC undergoing RARC.
A lightweight network model designed for alligator gar detection
Authors: Wang Xin , Shi Wei , Chen Rong 
Published: May 2024

AbstractWhen using advanced detection algorithms to monitor alligator gar in real-time in wild waters, the efficiency of existing detection algorithms is subject to certain limitations due to turbid water quality, poor underwater lighting conditions, and obstruction by other objects. In order to solve this problem, we developed a lightweight real-time detection network model called ARD-Net, from the perspective of reducing the amount of calculation and obtaining more feature map patterns. We introduced a cross-domain grid matching strategy to accelerate network convergence, and combined the involution operator and dual-channel attention mechanism to build a more lightweight feature extractor and multi-scale detection reasoning network module to enhance the network’s response to different semantics. Compared with the yoloV5 baseline model, our method performs equivalently in terms of detection accuracy, but the model is smaller, the detection speed is increased by 1.48 times, When compared with the latest State-of-the-Art (SOTA) method, YOLOv8, our method demonstrates clear advantages in both detection efficiency and model size,and has good real-time performance. Additionally, we created a dataset of alligator gar images for training.
Evaluation of the immune system status and hematological dyscrasias, among amphetamine and cannabis abusers at Eradah Hospital in Qassim, Saudi Arabia
Authors: Mohammed Amal Hussain , Aljarallah Atheer Saleh , Huq Mohsina , Mackawy Amal M. H. , Alharbi Basmah F. , Almutairi Khulud Salem , Alruwetei Abdulmohsen M. , Almatroudi Ahmad Abdulaziz A. , Alharbi Hajed Obaid , Aljohery Said Abdel Mohsen A. , Wasti Afshan Zeeshan 
Published: May 2024

AbstractThis cross-sectional study aims to evaluate the immune system status and hematological disturbances among individuals who abuse amphetamines and cannabis. Substance abuse, particularly of amphetamines and cannabis, has been associated with various adverse effects on the body, including potential impacts on the immune system and hematological parameters. However, limited research has been conducted to comprehensively assess these effects in a cross-sectional design. Additionally, fungal infections are on the rise internationally, and immune-compromised people are particularly susceptible. The study will recruit a sample of amphetamine and cannabis abusers (n = 50) at the Eradah Hospital in the Qassim Region of Buraydah and assess their sociodemographic and biochemical variables, including blood indices and differential WBC indices, liver, and kidney profiles. Additionally, 50 sputum samples in total were cultured for testing for fungus infections. To obtain the descriptive statistics, the data was imported into Microsoft Excel and subjected to statistical analysis using SPSS 22.0. Amphetamine and cannabis abuser's sociodemographic variables analysis observed that the majority (52%) were aged 18–30, with 56% in secondary school. Unemployment was a significant issue, and most had no other health issues. The majority (50%) had 5–10 years of abuse, while 32% had less than 5 years, and only 18% had been drug abusers for more than 10 years. There were significant changes (p < 0.001) in all different leukocyte blood cells, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. Furthermore, a microscopic examination of blood films from individuals who misuse the combination of the medications "amphetamine and cannabis" reveals hazardous alterations in Neutrophils. Out of 50, 35 sputum samples showed positive growth on Sabouraud dextrose agar (SDA) with chloramphenicol antibiotic, indicating a unicellular fungal growth. The present study explores the immune system and hematological disturbances linked to amphetamine and cannabis abuse, providing insights into health risks and targeted interventions. The findings complement previous research on drug users' hematological abnormalities, particularly in white blood cells. Routine hematological tests help identify alterations in homeostatic conditions, improving patient knowledge and preventing major issues. Further research is needed on multi-drug abuse prevention, early detection, and intervention. The cross-sectional design allows for a snapshot of the immune system and hematological status among abusers, laying the groundwork for future longitudinal studies. Key Words: Drug Effect, Immunity, Epidemiology, Oxidative Stress, Inflammation.
An extensive investigation on human risk associated with PAHs in fish and sediment in Bushehr, Northern of Persian Gulf
Authors: Nourian Ghafour , Jaafarzadeh Haghighi Fard Neamat , Pazira Abdul Rahim , Kohgardi Esmaeil 
Published: May 2024

AbstractHere, a comprehensive study was designed to estimate the human risk assessment attributed to exposure of polycyclic aromatic hydrocarbons (PAHs)in sediment and fish in most polluted shore area in north of Persian Gulf. To this end, a total of 20 sediment and inhabitual Fish, as one of most commercial fish, samples were randomly collected from 20 different stations along Bushehr Province coastline. The 16 different components of PAHs were extracted from sediment and edible parts of inhabitual fish and measured with high-performance liquid chromatography (HPLC) and gas chromatography (GC), respectively. In addition, dietary daily intake (DDI) values of PAHs via ingestion Indian halibut and the incremental lifetime cancer risk (ILCR) attributed to human exposure to sediments PAHs via (a) inhalation, (b) ingestion, and (c) dermal contact for two groups of ages: children (1–11 years) and adults (18–70 years) were estimated. The results indicated that all individual PAHs except for Benzo(b)flouranthene (BbF) and Benzo(ghi) perylene (BgP) were detected in different sediment sample throughout the study area with average concentration between 2.275 ± 4.993 mg.kg–1 dw. Furthermore, Naphthalene (Nap) with highest average concentration of 3.906 ± 3.039 mg.kg–1 dw was measured at the Indian halibut. In addition, the human risk analysis indicated that excess cancer risk (ECR) attributed to PAHs in sediment and fish in Asaluyeh with high industrial activities on oil and derivatives were higher the value recommended by USEPA (10−6). Therefore, a comprehensive analysis on spatial distribution and human risk assessment of PAHs in sediment and fish can improve the awareness on environmental threat in order to aid authorities and decision maker to find a sustainable solution.
Analysis of numerical modeling of steady-state modes of methane–hydrogen mixture transportation through a compressor station to reduce CO2 emissions
Authors: Fetisov Vadim 
Published: May 2024

AbstractThis study presents a mathematical model to evaluate the performance of gas pipelines during hydrogen injection in a gas pipeline-compressor station. The developed model presents the calculation of methane–hydrogen mixture (CH4/H2) transportation through the compressor station, where the compensation of pressure drops in the mass and energy balance takes place. Simultaneously, in the operation of the centrifugal blower system of gas compressor stations, the emissions of CO2 are considered, considering the mixing of gas media and the compression of CH4/H2. This mathematical model is realized for the pipeline transportation of hydrogen, at which the principle of mixture expansion occurs. The aim is to solve the problem of CO2 emissions at compressor stations. The optimization procedure has been formulated using a system of nonlinear algebraic equalities. The research focuses on the adaptation of existing gas transportation systems to CH4/H2 transportation and the impact of environmental risks on the operation of compressor station equipment. In this case, it is possible to determine the quantitative amount of hydrogen that can be added to natural gas. By solving the problem of finding the inner point of sets using the system of nonlinear algebraic equalities, it is possible to obtain the control parameters for safety control of technological modes of CH4/H2 mixture transportation. The study findings reveal that the consumption of gas charger and hydrogen was 50.67 and 0.184 kg/s, respectively, and the estimated efficiency resulting from the modified turbine design was 75.1 percent. These results indicate that the equipment operates more efficiently when hydrogen is being transported. The numerical analytical results indicated in this study hold practical significance for design applications. It will assist in identifying and evaluating the restrictions that may develop during the technological, operational, and design stages of decision-making.
Prediction and mediation analysis for treatment responses to combined cognitive and physical training for older adults
Authors: Chuang I.-Ching , Chen I.-Chen , Wu Yih-Ru , Li Kuan-Yi 
Published: May 2024

AbstractDiminished cognitive and physical functions negatively affect the daily functions of individuals. Although combined cognitive and physical training prevents instrumental activities of daily living (IADL) disability in older adults, no predictive model or mediation analysis of IADL after combined training exists. This study aims to employ prediction and mediation analysis to identify the predictors of IADL performance and to elucidate the mediators of the association between baseline global cognition and subsequent IADL performance following combined cognitive and physical training. This study involved 177 participants aged 60 years and older who underwent combined training. Cognitive function was measured with the Montreal Cognitive Assessment (MoCA), Digit Symbol Substitution Test (DSST), Color Trails Test, Word List, and a dual task; physical function with the Timed Up and Go (TUG) test; daily function with the Lawton IADL Scale. We conducted regression analyses to identify the predictors of IADL performance, and mediation analysis to examine whether DSST and TUG mediate the relationship between MoCA and IADL. The pre-intervention DSST and TUG were significant independent predictors of post-intervention IADL. The association between the pre-intervention MoCA and post-intervention IADL was mediated by pre-intervention DSST and TUG. This study highlighted the importance of measuring and improving processing speed and functional mobility before and during interventions to enhance IADL outcomes.Trial registration: NCT03619577, 23/07/2018; NCT04689776, 29/12/2020.
A fungi hotspot deep in the ocean: explaining the presence of Gjaerumia minor in equatorial Pacific bathypelagic waters
Authors: Pernice Massimo C. , Forn Irene , Logares Ramiro , Massana Ramon 
Published: May 2024

AbstractA plant parasite associated with the white haze disease in apples, the Basidiomycota Gjaerumia minor, has been found in most samples of the global bathypelagic ocean. An analysis of environmental 18S rDNA sequences on 12 vertical profiles of the Malaspina 2010 expedition shows that the relative abundance of this cultured species increases with depth while its distribution is remarkably different between the deep waters of the Pacific and Atlantic oceans, being present in higher concentrations in the former. This is evident from sequence analysis and a microscopic survey with a species-specific newly designed TSA-FISH probe. Several hints point to the hypothesis that G. minor is transported to the deep ocean attached to particles, and the absence of G. minor in bathypelagic Atlantic waters could then be explained by the absence of this organism in surface waters of the equatorial Atlantic. The good correlation of G. minor biomass with Apparent Oxygen Utilization, recalcitrant carbon and free-living prokaryotic biomass in South Pacific waters, together with the identification of the observed cells as yeasts and not as resting spores (teliospores), point to the possibility that once arrived at deep layers this species keeps on growing and thriving.
Global arthropod beta-diversity is spatially and temporally structured by latitude
Authors: Seymour Mathew , Roslin Tomas , deWaard Jeremy R. , Perez Kate H. J. , D’Souza Michelle L. , Ratnasingham Sujeevan , Ashfaq Muhammad , Levesque-Beaudin Valerie , Blagoev Gergin A. , Bukowski Belén , Cale Peter , Crosbie Denise , Decaëns Thibaud , deWaard Stephanie L. , Ekrem Torbjørn , El-Ansary Hosam O. , Evouna Ondo Fidèle , Fraser David , Geiger Matthias F. , Hajibabaei Mehrdad , Hallwachs Winnie , Hanisch Priscila E. , Hausmann Axel , Heath Mark , Hogg Ian D. , Janzen Daniel H. , Kinnaird Margaret , Kohn Joshua R. , Larrivée Maxim , Lees David C. , León-Règagnon Virginia , Liddell Michael , Lijtmaer Darío A. , Lipinskaya Tatsiana , Locke Sean A. , Manjunath Ramya , Martins Dino J. , Martins Marlúcia B. , Mazumdar Santosh , McKeown Jaclyn T. A. , Anderson-Teixeria Kristina , Miller Scott E. , Milton Megan A. , Miskie Renee , Morinière Jérôme , Mutanen Marko , Naik Suresh , Nichols Becky , Noguera Felipe A. , Novotny Vojtech , Penev Lyubomir , Pentinsaari Mikko , Quinn Jenna , Ramsay Leah , Rochefort Regina , Schmidt Stefan , Smith M. Alex , Sobel Crystal N. , Somervuo Panu , Sones Jayme E. , Staude Hermann S. , St. Jaques Brianne , Stur Elisabeth , Telfer Angela C. , Tubaro Pablo L. , Wardlaw Tim J. , Worcester Robyn , Yang Zhaofu , Young Monica R. , Zemlak Tyler , Zakharov Evgeny V. , Zlotnick Bradley , Ovaskainen Otso , Hebert Paul D. N. 
Published: May 2024

Abstract
Global biodiversity gradients are generally expected to reflect greater species replacement closer to the equator. However, empirical validation of global biodiversity gradients largely relies on vertebrates, plants, and other less diverse taxa. Here we assess the temporal and spatial dynamics of global arthropod biodiversity dynamics using a beta-diversity framework. Sampling includes 129 sampling sites whereby malaise traps are deployed to monitor temporal changes in arthropod communities. Overall, we encountered more than 150,000 unique barcode index numbers (BINs) (i.e. species proxies). We assess between site differences in community diversity using beta-diversity and the partitioned components of species replacement and richness difference. Global total beta-diversity (dissimilarity) increases with decreasing latitude, greater spatial distance and greater temporal distance. Species replacement and richness difference patterns vary across biogeographic regions. Our findings support long-standing, general expectations of global biodiversity patterns. However, we also show that the underlying processes driving patterns may be regionally linked.
Hyperthyroidism-driven bone loss depends on BMP receptor Bmpr1a expression in osteoblasts
Authors: Lademann Franziska , Rijntjes Eddy , Köhrle Josef , Tsourdi Elena , Hofbauer Lorenz C. , Rauner Martina 
Published: May 2024

AbstractHyperthyroidism is a well-known trigger of high bone turnover that can lead to the development of secondary osteoporosis. Previously, we have shown that blocking bone morphogenetic protein (BMP) signaling systemically with BMPR1A-Fc can prevent bone loss in hyperthyroid mice. To distinguish between bone cell type-specific effects, conditional knockout mice lacking Bmpr1a in either osteoclast precursors (LysM-Cre) or osteoprogenitors (Osx-Cre) were rendered hyperthyroid and their bone microarchitecture, strength and turnover were analyzed. While hyperthyroidism in osteoclast precursor-specific Bmpr1a knockout mice accelerated bone resorption leading to bone loss just as in wildtype mice, osteoprogenitor-specific Bmpr1a deletion prevented an increase of bone resorption and thus osteoporosis with hyperthyroidism. In vitro, wildtype but not Bmpr1a-deficient osteoblasts responded to thyroid hormone (TH) treatment with increased differentiation and activity. Furthermore, we found an elevated Rankl/Opg ratio with TH excess in osteoblasts and bone tissue from wildtype mice, but not in Bmpr1a knockouts. In line, expression of osteoclast marker genes increased when osteoclasts were treated with supernatants from TH-stimulated wildtype osteoblasts, in contrast to Bmpr1a-deficient cells. In conclusion, we identified the osteoblastic BMP receptor BMPR1A as a main driver of osteoporosis in hyperthyroid mice promoting TH-induced osteoblast activity and potentially its coupling to high osteoclastic resorption.
Distributed and dynamical communication: a mechanism for flexible cortico-cortical interactions and its functional roles in visual attention
Authors: Ni Shencong , Harris Brendan , Gong Pulin 
Published: May 2024

AbstractPerceptual and cognitive processing relies on flexible communication among cortical areas; however, the underlying neural mechanism remains unclear. Here we report a mechanism based on the realistic spatiotemporal dynamics of propagating wave patterns in neural population activity. Using a biophysically plausible, multiarea spiking neural circuit model, we demonstrate that these wave patterns, characterized by their rich and complex dynamics, can account for a wide variety of empirically observed neural processes. The coordinated interactions of these wave patterns give rise to distributed and dynamic communication (DDC) that enables flexible and rapid routing of neural activity across cortical areas. We elucidate how DDC unifies the previously proposed oscillation synchronization-based and subspace-based views of interareal communication, offering experimentally testable predictions that we validate through the analysis of Allen Institute Neuropixels data. Furthermore, we demonstrate that DDC can be effectively modulated during attention tasks through the interplay of neuromodulators and cortical feedback loops. This modulation process explains many neural effects of attention, underscoring the fundamental functional role of DDC in cognition.
Scientists’ identities shape engagement with environmental activism
Authors: Finnerty Samuel , Piazza Jared , Levine Mark 
Published: May 2024

AbstractScientists are increasingly joining environmental movements. As knowledge producers and influential figures in society, scientists are uniquely positioned to drive change. Here we explore how scientist identity shapes engagement in environmental activism using qualitative and quantitative data from a multinational survey of 329 scientists from 41 countries. Scientist identity content, specifically perception of the science-activism relationship, was a stronger explanatory variable than strength of identification as a scientist. Perceiving a harmonious relationship between science and activism, endorsing environmental stewardship as a scientist’s duty, and believing objectivity and impartiality remained uncompromised by activism, each had significant correlations with engagement. These components formed a composite variable, which remained a robust explanatory variable of engagement even when accounting for the influence of activist identity. Scientists embracing scientist-activist compatibilism were also less inclined to view new technologies as a panacea for the climate crisis. This research underscores the important role of scientist identity content in shaping climate actions and perspectives.
The impact of agricultural credit on the cattle inventory and deforestation in Colombia: a spatial analysis
Authors: Mejía Tejada Daniela , Díaz Baca Manuel Francisco , Enciso Valencia Karen Johanna , Bravo Parra Aura María , Flórez Jesús Fernando , Junca Paredes John Jairo , Burkart Stefan 
Published: May 2024

AbstractThe relationship between agricultural credit and agricultural production as well as the impacts on sustainable development (i.e., poverty alleviation, reduction of inequalities, food and nutrition security, and stimulation of economic growth) have been widely documented. The objective of this study is to analyze the impact of credit on cattle production and deforestation in Colombia through spatial panel data models. For this purpose, a departmental data panel for the period 2011–2020 was built, based on available information from public entities. The results suggest that in Colombia, the relationship between access to credit and cattle production is significant and can be either negative or positive. In addition, there is evidence of spatial dependence, meaning that cattle production in one department is being affected by cattle production in a neighboring department or by all the departments that make up the national territory. Regarding deforestation, results show that, although the number of cattle present in a department does affect its annual deforestation rate due to a poor coverage of sustainably intensified cattle ranching systems, there is no relationship between deforestation and the access to credit nor any spatial correlations.
Landing a global report on national territories: the reception of AR6 in France and Switzerland
Authors: Gaveau Adèle 
Published: May 2024

AbstractThis article explores the reception of the IPCC reports on a national scale, focusing on the case of the Sixth Assessment Report (AR6) in France and Switzerland. It sheds light on the orchestration processes of national reception by the actors involved in the two science-policy interfaces, and introduces the theoretical concept of “landing” for the comparative analysis. Using mixed qualitative methods, it reveals that in both case studies, the domestic science-policy interactions stemming from the landing deviated significantly from expectations. Unusual actors different from the IPCC National Focal Points got involved in framing the conditions of the report’s domestic reception, and AR6 faced challenges when entering national Parliament. The results are discussed within the broader context of a global reflection on the imperative to enhance the dissemination channels of the IPCC scientific results to political audiences.