bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lymph Node Evolution in Eyelid and Orbit Squamous Cell Carcinomas
Authors: Chebib Emilien , Rougier Guillaume , Dubray‐Vautrin Antoine , Martin Joey , Ghanem Wahib , Lesnik Maria , Sabran Baptiste , Matet Alexandre , Malaise Denis , Cassoux Nathalie , Dendale Rémi , Choussy Olivier , Badois Nathalie 
Published: June 2024

ObjectivesTo describe a large cohort of eyelid and periorbital SCCs, to compare the location of the tumor and of the pathological lymph nodes, and to analyze the risk factors for lymph node involvement among tumor characteristics.MethodsAll patients managed inside our institution for an eyelid and periorbital SCCs were included. Tumor characteristics, imaging setup, excision margins, lymph node evolution features, local, regional, and distant recurrences rates, and global survival were reported. The risk for lymph node involvement and location of pathological lymph nodes were analyzed through univariate and multivariate analyses.ResultsBetween January 2012 and August 2022, 115 patients were included, and 18 presented a lymph node evolution (15.7%), involving the parotid gland in 16 cases (88.9%), the submental and submandibular areas in seven cases (38%), and the jugular and carotid areas in four cases (22%). Tumor size above 20 mm, infiltration of the external canthus and periorbital structures, the presence of perineural invasion or vascular embolism, the depth of infiltration, and the presence of a local recurrence were significantly associated with the risk of lymph node evolution.ConclusionPeriorbital and eyelid SCCs present a true potential for lymph node evolution especially through the parotid gland. Extension setup including the parotid gland and neck should be mandatory, and lymph node dissection should be associated in case of parotidectomy for lymph node involvement.Level of Evidence4 Laryngoscope, 134:4956–4963, 2024
Phytoconstituents of Citrus limon (Lemon) as Potential Inhibitors Against Multi Targets of SARS‐CoV‐2 by Use of Molecular Modelling and In Vitro Determination Approaches
Authors: Raman Kannan , Kalirajan Rajagopal , Islam Fahadul , Jupudi Srikanth , Selvaraj Divakar , Swaminathan Gomathi , Singh Laliteshwar Pratap , Rana Ritesh , Akash Shopnil , Islam Md. Rezaul , Nainu Firzan , Emran Talha Bin , Dawoud Turki M. , Bourhia Mohammed , Dauelbait Musaab , Barua Rashu 
Published: June 2024

AbstractIn the present work, phytoconstituents from Citrus limon are computationally tested against SARS‐CoV‐2 target protein such as Mpro ‐ (5R82.pdb), Spike ‐ (6YZ5.pdb) &RdRp ‐ (7BTF.pdb) for COVID‐19. Docking was done by glide model, QikProp was performed by in silico ADMET screening & Prime MM‐GB/SA modules were used to define binding energy. When compared with approved COVID‐19 drugs such as Remdesivir, Ritonavir, Lopinavir, and Hydroxychloroquine, plant‐based constituents such as Quercetin, Rutoside, Naringin, Eriocitrin, and Hesperidin. bind with significant G‐scores to the active SARS‐CoV‐2 place. The constituents Rutoside and Eriocitrin were studied in each MD simulation in 100 ns against 3 proteins 5R82.pdb, 6YZ5.pdb and 7BTF.pdb.We performed an assay with significant natural compounds from contacts and in silico results (Rutin, Eriocitrin, Naringin, Hesperidin) using 3CL protease assay kit (B.11529 Omicron variant). This kit contained 3CL inhibitor GC376 as Control. The IC50 value of the test compound was found to be Rutin −17.50 μM, Eriocitrin−37.91 μM, Naringin−39.58 μM, Hesperidine−140.20 μM, the standard inhibitory concentration of GC376 was 38.64 μM. The phytoconstituents showed important interactions with SARS‐CoV‐2 targets, and potential modifications could be beneficial for future development.
Current advances in the pain treatment and mechanisms of Traditional Chinese Medicine
Authors: Zhu Xiaoli , Jia Zhuolin , Zhou Ye , Wu Jie , Cao Mayijie , Hu Changjiang , Yu Lingying , Chen Zhimin 
Published: June 2024

AbstractTraditional Chinese Medicine (TCM), as a unique medical model in China, has been shown to be effective in the treatment of many diseases. It has been proven that TCM can increase the pain threshold, increase the level of endorphins and enkephalins in the body, and reduce the body's response to adverse stimuli. In recent years, TCM scholars have made valuable explorations in the field of pain treatment, using methods such as internal and external application of TCM and acupuncture to carry out research on pain treatment and have achieved more satisfactory results. TCM treats pain in a variety of ways, and with the discovery of a variety of potential bioactive substances for pain treatment. With the new progress in the research of other TCM treatment methods for pain, TCM will have greater potential in the clinical application of pain.
A New Protocol for Semi‐quantum Private Set of Intersection and Union Mixed Cardinality for Any Tripartite Based on Bell States
Authors: Chi Yue‐Ping , Zhang Yu , Zhang Ke‐Jia , Xu Gang , Chen Xiu‐Bo 
Published: June 2024

AbstractThe cardinality of the private set allows multiple parties to jointly compute the cardinality of the intersection and union without revealing their respective private sets. It plays an important role in data mining and data analysis to protect privacy. However, existing studies only focus on computing the cardinality of the intersection or union of private sets. To extend its application in various scenes, a private‐set intersection and union mixed cardinality protocol are proposed for any tripartite based on Bell states for the first time. During the protocol, participants are supposed to be semi‐quantum to reduce the consumption of quantum resources and improve the realizability of the protocol. Furthermore, correctness and security analysis show that the protocol can withstand internal and external attacks. Additionally, the IBM Quantum Simulator (IBMQS) is also applied to illustrate the fundamentals of the protocol and verify the availability of the protocol. The results are expected have positive effects on the further development of secure multiparty computation.
Transoral robotic surgery in the diagnosis and treatment of primary unknown head and neck squamous cell carcinoma: A preliminary single centre experience
Authors: Zhi Yinghui , Zhang Yabing , Zhang Bin 
Published: June 2024

AbstractBackgroundSquamous cell carcinoma of unknown primary (CUP) in the head and neck is difficult to diagnose and treat. This report outlines 11 cases of CUP treated with transoral robotic surgery (TORS), aimed at investigating the diagnostic efficiency of primary tumour and radical resection effectiveness of TORS.Methods11 cases of CUP among 68 oropharyngeal cancer patients treated by TORS were analysed retrospectively.ResultsAll the 11 cases received TORS with cervical lymph node dissection. Primary tumours were found in 8 cases (72.7%), 4 cases in the palatine tonsil and 4 cases in the base of the tongue. The average diameter of the primary tumour was 1.65 cm. All patients resumed eating by mouth within 24 h, no tracheotomy, no pharyngeal fistula and no postoperative death. The 3‐year disease‐free survival rate was 91%.ConclusionsTORS can improve the diagnostic efficiency of primary tumour of CUP and achieve good oncology and functional results.
Transition to a Science Mega-Project, 2006–2012
Authors: Schilizzi Richard T. , Ekers Ronald D. , Dewdney Peter E. , Crosby Philip 
Published: June 2024

AbstractFollowing the “Grass-roots” astronomer-led phase of global collaboration in the SKA project described in the previous Chapter, the transition of SKA to a science mega-project (the “Transition Era”) began in 2006. Three governance entities operated in conjunction in this period (i) the International SKA Steering Committee, (ii) the funding agencies acting collectively in a group, and (iii) the European Commission-funded SKA Preparatory Phase (PrepSKA) Board. This culminated in an Agreement at the end of 2011 amongst the funding agencies and governments to establish a legal entity for the project, the SKA Organisation (SKAO), in the UK in the form of a Company Limited by Guarantee, with governance vested solely in the company. The third phase of governance, the “Pre-Construction Era”, followed until January 2021 when a new governance arrangement, an Inter-Governmental Organisation, came into force for the construction and operation of the SKA Observatory.In this Chapter, we describe the Transition Era in terms of its evolving governance, the major activities carried out, bumps along the road including the US decision at the end of 2011 not to join the SKAO, and the first year of the Pre-Construction Era in 2012. The first major decision of the new SKAO, in mid-2012—where the SKA telescope would be located—is described in Chap. 8.
Innovation Meets Reality: The SKA Design
Authors: Schilizzi Richard T. , Ekers Ronald D. , Dewdney Peter E. , Crosby Philip 
Published: June 2024

AbstractThis chapter is an account of the creativity of a host of engineers and scientists to build a groundbreaking radio telescope with the performance needed to extract the scientific treasures buried in weak radio signals from the distant Universe, of which there were previously only hints. Always moving forward, it describes the road from the ambition to overcome barriers and harness new technologies to the reality of thousands of difficult individual decisions that had to be made to successfully yield a realisable design in the available time. The global milieu in which this was done as an international project has set many precedents.
Human Dignity as a Global Common Good
Authors: Hasegawa Ko 
Published: June 2024

AbstractThis article tackles the question of what makes human dignity so central in human morality and law, focusing not on specific understandings of human dignity but rather on the concept's universal significance. It argues that of importance are the singularity of human existence in the universe and in life, the manifestation of individuality in ethics and morality in general, and the awareness of these characteristics as grounded in the fundamental natural and societal conditions for human beings. Further, this article maintains that such a status of human dignity is a foundational focus of the broader normative space that has evolved throughout human history; that normative points of human dignity can be globalized in the process of communicative networking; and thus that human dignity is a fundamental, universal, and shared human condition constituting a global common good.
Casting light on integer compositions
Authors: Blecher Aubrey , Knopfmacher Arnold , Mays Michael 
Published: June 2024

AbstractInteger compositions of n are viewed as bargraphs with n circular nodes or square cells in which the ith part of the composition $$x_i$$

x
i

is given by the ith column of the bargraph with $$x_i$$

x
i

nodes or cells. The sun is at infinity in the north west of our two dimensional model and each node/cell may or may not be lit depending on whether it stands in the shadow cast by another node/cell to its left. We study the number of lit nodes in an integer composition of n and later we modify this to yield the number of lit square cells. We then count the number of columns being lit which leads naturally to those cases where only the first column is lit. We prove the theorem that the generating function for the latter is the same as the generating function for compositions in which the first part is strictly smallest. This theorem has interesting q-series identities as corollaries which allow us to deduce in a simple way the asymptotics for both the number of lit nodes and columns as $$n \rightarrow \infty $$

n
→
∞

.
Navigating the labyrinth of peritoneal and extraperitoneal anatomy: abdominal spread made easy with a case based review
Authors: Polamraju Praveen , Oliphant Michael , Aribindi Swetha , Ponnatapura Janardhana 
Published: June 2024

AbstractEssential to understanding disease spread in abdomen is to separate the peritoneum from the extraperitoneum. These areas have distinct anatomy with well-define separate pathways. The peritoneum is comprised of connected recesses that are potential spaces, normally not imaged except when containing excess fluid or air. Peritoneal recesses are formed by the opposing peritoneal surfaces and subdivided by the attachments of the ligaments and mesenteries to the parietal peritoneum. Disease flows within the recesses by changes in abdominal pressure. This forms a distinct spread pattern. The extraperitoneum is traditionally stratified by the renal fascia into the anterior and posterior pararenal spaces and the perirenal space. The fascia contains and directs spread from the contained organs with the compartments. Each space has a unique spread pattern defined by the containing fascia. The extraperitoneum is connected to the mesenteries and ligaments forming the subperitoneal space. This space interconnects the extraperitoneum with the mesenteries allowing for the normal continuum of blood vessels, lymphatics, and nerves but also forms the pathways for bidirectional spread of disease.
Card-based Cryptography with a Standard Deck of Cards, Revisited: Efficient Protocols in the Private Model
Authors: Nakai Takeshi , Iwanari Keita , Ono Tomoki , Abe Yoshiki , Watanabe Yohei , Iwamoto Mitsugu 
Published: June 2024

AbstractCard-based cryptography is a secure computation protocol realized by using physical cards. There are two models on card-based cryptography: public and private models. We adopt private one that allows players to handle cards privately. While much of the existing works for card-based cryptography use two-colored cards, it is also a vital task to construct an efficient protocol with playing cards. In the public model, 2n cards are necessary for any n-bit input protocol since at least two cards are required to express a Boolean value. It holds true for both two-colored and playing-card settings. On the other hand, the private model enables us to construct a protocol with fewer than 2n cards. However, all existing protocols that achieve such properties are only in the two-colored setting. This paper shows that the private model enables us to construct a protocol with fewer than 2n cards using the playing cards. We first show two-bit input protocols with fewer than four cards for logical operations, AND, OR, and XOR. Furthermore, we show a three-input majority voting protocol using only three cards, which is constructed by combining our AND and OR protocols. Notably, our proposed protocols require no randomness. All operations are deterministic and depend only on players’ private inputs.
A Coarse Grained Molecular Dynamics Model for the Simulation of Lubricating Greases
Authors: Benois Anthony , Echeverri Restrepo Sebastián , De Laurentis Nicola , Hogenberk Femke , Giuntoli Andrea , Lugt Piet M. 
Published: June 2024

AbstractThe rheological properties of lubricating greases are determined by the viscosity of the base oil, the interaction between base oil and thickener, and the interaction between thickener particles. The contribution of the oil–thickener interactions to the viscosity is well known, but the contribution of the thickener–thickener interactions has not yet been studied by employing theoretical or computational frameworks. In this paper, we use coarse-grained molecular dynamics to simulate a fibrous microstructure, and we show that the experimentally observed viscoelastic/plastic behaviour can be well reproduced. A parametric study shows that the apparent viscosity increases with increasing fibre length, fibre stiffness and thickener concentration. This is as expected, showing that this modelling approach is useful to study effects on grease rheology that are not accessible experimentally, such as impact of fibre entanglement or agglomeration.
The organisational impact of agility: a systematic literature review
Authors: Nguyen Tien , Le Cat Vi , Nguyen Minh , Nguyen Gam , Lien Tran Thi Hong , Nguyen Oanh 
Published: June 2024

AbstractThis paper reviews the literature on agility and its relationship with organisational performance using a sample of 249 recent empirical studies from 1998 to February 2024. We find support for a relatively strong and consistent contribution of different aspects of agility to organisational performance. Our analysis highlights numerous salient issues in this literature in terms of the theoretical background, research design, and contextual factors in agility-performance research. On this basis, we propose relevant recommendations for future research to address these issues, specifically focusing on the role of the board of directors and their leadership in fostering organisational agility.
A Better Argument for Tawḥīd?: Philosophical Discussions of Divine Attributes in the Sharḥ Al-ʿaqāid Tradition
Authors: Arslan Mehmet Fatih 
Published: June 2024

Abstract
This study focuses on al-Taftāzānī’s discussion of the ontological status of divine attributes in his Sharḥ al-ʿAqāid and aims to demonstrate that al-Rāzī’s (d. 606/1210) reluctantly and ambiguously proposed formula that divine attributes are possible by themselves and necessary by God, which itself is an adaptation of Avicennian formula about the ontological status of the divine intellects, received much more recognition after a more sophisticated and advanced version of it was introduced to Sunnī kalām tradition by al-Taftāzānī (d. 792/1390). His improvements generated a considerable amount of intellectual interest within the subsequent commentary and super-commentary tradition and were then refined by the later commentators, a crucial development which has been almost entirely neglected in the modern scholarship. This study further argues that the orientation of post-classical kalām extends to the point where it embraces a specific formula promoted by the Falāsifa to refine Sunnī theory about the ontological status of the divine attributes. Consequently, Sunnī theology deliberately adapted a previously rejected theory to one of its most exclusive and core subjects, that is the discussion of the divine attributes. This study will also show that dramatic transformations in the approach and the structure indicate that Sunnī kalām, especially in Sharḥ al-ʿAqāid commentaries and super-commentaries, was significantly influenced by philosophical theories and was required to adopt both the vocabulary and the framework fashioned in philosophical debates on a greater scale after its first transformation due to al-Rāzī’s influence. Because of the voluminous commentaries and super-commentaries on Sharḥ al-ʿAqāid and their extended coverage of a variety of subjects, the current study limits itself to al-Taftāzānī’s Sharḥ al-ʿAqāid and its super-commentaries by Musa Khayālī (d. 862/1457) and Ramazan Efendi al-Ḥanafī (d. 1025/1616?).
Effects of planned training and music listened to before a cesarean section on surgical fear, anxiety and depression: A randomized controlled trial
Authors: Guney Demet , Pinar Sukran Ertekin 
Published: June 2024

Abstract
Purpose
This research was conducted to determine the impact of a planned training program and music on fear, anxiety, and depression among women undergoing cesarean section.

Methods
The sample of the randomized-controlled experimental study consisted of a total of 120 pregnant women (music 40, training 40, and the control 40) scheduled for cesarean section at the Obstetrics Service. Instrumental music from the Turkish music modes (the Hejaz, Neva, and Acemaşıran modes) was played for the music group, a planned training was given for the training group (what a cesarean section is, why a cesarean section should be performed, breastfeeding, mobilization, etc.) before the cesarean section, and no additional interventions were made for the control group. The data were collected using the Personal Information Form, Surgical Fear Questionnaire, and the Hospital Anxiety and Depression Scale.

Results
After the planned training and listening to music applications, statistically significant differences were found between the music, training, and the control groups in terms of the short-term, long-term sub-scale scores and the overall score of the Surgical Fear Questionnaire and the anxiety sub-scale scores of the Hospital Anxiety and Depression Scale (p < 0.05).

Conclusions
Listening to music before the cesarean section was effective in reducing women’s short-term and general surgical fears, and the training was also effective in reducing their short-term, long-term, and general surgical fears and anxiety levels. However, the applications did not change depression levels. According to these findings, listening to music and provision of training are recommended to reduce surgical fears and anxiety levels of women before a planned cesarean section.
The Utility of Socioeconomic and Remoteness Indicators in Understanding the Geographical Variation in the Regional Prevalence of Early Childhood Vulnerability in Australia
Authors: Baffour Bernard , Das Sumonkanti , Li Mu , Richardson Alice 
Published: June 2024

AbstractThe family lives of children and their early childhood development outcomes are attributable to the level of socio-economic disadvantage and relative isolation. This study aims to investigate how the disadvantage of the local area (i.e., socio-economic indexes for areas (SEIFA)) and the remoteness (i.e., accessibility/remoteness index of Australia (ARIA)) contribute to improved prevalence estimates of child development vulnerability in statistical areas level 3 (SA3) and 4 (SA4) across Australia. Data from the 2018 Australian Early Development Census (AEDC) has been used. The study included 308,953 children involved in the AEDC 2018 where one-in-ten of them were considered to be developmentally vulnerable, nationally. We developed models in a hierarchical Bayesian framework at the SA3 level using SEIFA and ARIA indices as covariates to account for spatial and unobserved heterogeneity. The performances of developed models are examined based on the consistency at SA3, SA4, and state level. The results reveal that SEIFA makes a significant contribution to explaining the spatial variation in childhood development vulnerability across small domains in Australia. Further, the inclusion of the ARIA score improves the model performance and provides better accuracy, particularly in remote and very remote regions. In these regions, the spatial model fails to distinguish the remoteness characteristics. The chosen non-spatial model accounting for heterogeneity at higher hierarchies performs best. The utilization of socio-economic disadvantage and geographic remoteness of the finer level domains helps to explain the geographic variation in child development vulnerability, particularly in sparsely populated remote regions in Australia.