bluuebunny/crossref_metadata_2025_split huggingface dataset:
Afterword: Primitivism under Erasure
Authors: Gikandi Simon 
Published: June 2024

Abstract
Of all the terms that came to define the making of culture and art in the long twentieth century, there was perhaps none as necessary and troublesome as primitivism and the tropes associated with it. This afterword is a reflection on the collection of articles in this special issue struggling with the question of how to work with disputed terms such as primitivism, and to consider the possibilities and limits of the aesthetic ideology of modernism and its alternative iterations.
Adaptive Seamless Dose-Finding Trials
Authors: Chen Ningyuan , Khademi Amin 
Published: June 2024

Problem definition: We study early-stage dose-finding clinical trials with simultaneous consideration of efficacy and toxicity without parametric assumptions on the forms of the unknown dose-efficacy and dose-toxicity curves. We propose algorithms that adaptively allocate doses based on patient responses, in order to maximize the efficacy for the patients during the trial while minimizing the toxicity. Methodology/results: We leverage online learning to design the clinical trial and propose two algorithms. The first one follows dose-escalation principles and analyzes the efficacy and toxicity simultaneously. The second one uses bisection search to identify a safe dose range and then applies upper confidence bound algorithms within the safe range to identify efficacious doses. We show the matching upper and lower bounds for the regret of both algorithms. We find that observing the dose-escalation principle is costly, as the optimal regret of the first algorithm is in the order of [Formula: see text], worse than the optimal regret of the second algorithm, which is in the order of [Formula: see text]. We test our proposed algorithms with three benchmarks commonly used in practice on synthetic and real data sets, and the results show that they are competitive with or significantly outperform the benchmarks. Managerial implications: We provide a novel insight that following the dose-escalation principle inevitably leads to higher regret. The first proposed algorithm is suitable to use when little information about the dose-toxicity profile is available, whereas the second one is appealing when more information is available about the toxicity profile. Funding: This work was supported by the National Science Foundation [Grant 1651912]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.0246 .
Statins, metformin, and RAS inhibitors did not reduce variceal bleeding risk and mortality in a large, real-life cohort of patients with cirrhosis
Authors: Pfisterer Nikolaus , Schwarz Michael , Schwarz Caroline , Putre Florian , Ritt Lukas , Riedl Florian , Hartl Lukas , Jachs Mathias , Mandorfer Mattias , Madl Christian , Trauner Michael , Reiberger Thomas 
Published: June 2024

Background
Previous experimental and clinical studies suggested a beneficial effect of statins, metformin, angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers (RASi) on portal hypertension. Still, their effects on hard cirrhosis-related clinical endpoints, such as variceal bleeding and bleeding-related mortality, remain to be investigated.

Methods
Thus, we recorded the use of statins, metformin and RASi in a large cohort of cirrhotic patients undergoing endoscopic band ligation (EBL) for primary (PP, n = 440) and secondary bleeding prophylaxis (SP, n = 480) between 01/2000 and 05/2020. Variceal (re-) bleeding and survival rates were compared between patients with vs. without these co-medications.

Results
A total of 920 cirrhotic patients with varices were included. At first EBL, median MELD was 13 and 515 (56%) patients showed ascites. Statins, metformin and RASi were used by 49 (5.3%), 74 (8%), and 91 (9.9%) patients, respectively. MELD and platelet counts were similar in patients with and without the co-medications of interest. Rates of first variceal bleeding and variceal rebleeding at 2 years were 5.2% and 11.7%, respectively. Neither of the co-medications were associated with decreased first bleeding rates (log-rank tests in PP: statins p = 0.813, metformin p = 0.862, RASi p = 0.919) nor rebleeding rates (log-rank tests in SP: statin p = 0.113, metformin p = 0.348, RASi p = 0.273). Similar mortality rates were documented in patients with and without co-medications for PP (log-rank tests: statins p = 0.630, metformin p = 0.591, RASi p = 0.064) and for SP (statins p = 0.720, metformin p = 0.584, RASi p = 0.118).

Conclusion
In clinical practice, variceal bleeding and mortality rates of cirrhotic patients were not reduced by co-medication with statins, metformin or RASi. Nevertheless, we recommend the use of these co-medications by indication, as they may still exert beneficial effects on non-bleeding complications in patients with liver cirrhosis.
Factors associated with the intention to use maternity waiting homes among pregnant women in North Ethiopia
Authors: Gebreslasie Kahsay Zenebe , Beyene Abrahaley Welay , Dewey Rebecca Susan , Gebrehawerya Tewelde 
Published: June 2024

Introduction
Maternity waiting homes are residential facilities, located near a qualified healthcare facility, where pregnant women can await their delivery and be transferred to a nearby healthcare facility shortly before delivery, or earlier if complications arise. Although evidence has shown that maternity waiting homes reduce maternal and neonatal mortality, there is limited information about factors associated with the intention to use maternity waiting homes in the study area. Therefore, the aim of this study was to identify factors associated with intention to use maternity waiting homes among pregnant women.

Methods
The study used a community-based cross-sectional study design. Simple random sampling was used to select 399 pregnant women. Data were collected using an interviewer-administered pre-tested structured questionnaire.A binary and multivariate logistic regression analysis was performed.

Result
Two hundred and eighty (70.2%) women indicated they intended to use a maternity waiting home during their current pregnancy. Participants’ educational status, having experienced a previous institutional delivery, the affordability of food while staying at the maternity waiting home, placing a burden on their attendant, having children in the household who can be cared for by the community or family during the woman’s absence, and having household chores covered by their family/community were the factors associated with the intention to use a maternity waiting home.

Conclusion
Relatively few respondents intended to use maternity waiting homes. Empowering women and giving them agency by ensuring their needs are met are important measures necessary to increase the use of maternity waiting homes.
Book-Sharing for Toddlers with Clefts (BOOST): Protocol for a randomized controlled trial of a remote intervention to promote language development in children with cleft palate
Authors: Collett Brent R. , Gallagher Emily R. , Johns Alexis L. , Trevino Cindy O. , Leroux Brian G. , Shic Frederick , Crerand Canice E. , Baylis Adriane L. , Cummings Caitlin A. , Santillan Lupita 
Published: June 2024

Background
Children with cleft palate, with or without cleft lip (CP±L), exhibit language delays on average compared to children without clefts. Interventions to address these disparities are scarce. In this multi-center study, Book Sharing for Toddlers with Clefts (BOOST), we will test a remote, parent-focused intervention to promote language development in children with CP±L.

Objectives
The study will test two primary hypotheses. First, toddlers randomized to BOOST will exhibit better language outcomes than children receiving standard-of-care (SOC). Second, we hypothesize that the BOOST program’s effect on language outcomes is mediated by the frequency and quality of parent-child reading interactions.

Methods
The study is a randomized-controlled trial comparing the BOOST group to a SOC comparison group. We will enroll N = 320 English and/or Spanish-speaking children ages 24–32 months with isolated CP±L (n = 160 per group). Both groups will receive children’s books, and parents will record and upload videos of themselves reading the books with their children using a smartphone app developed for the study. Parents will also complete surveys asking whether they read to their children on five randomly selected days each week. In addition, the BOOST group will participate in 3 remote dialogic book-sharing intervention sessions via Zoom. We will code book-sharing videos to assess parents’ target skill usage and children’s expressive language. End-of-study assessments will include measures of child language outcomes (e.g., clinician-administered measures, parent reports, and naturalistic child language samples).

Results
Enrollment began in April 2024 and will continue through approximately April 2028.

Conclusion
The BOOST study will address a critical gap in the literature on interventions to improve language in children with CP±L. The results will inform the care for toddlers with oral clefts and have potential applications for other populations.
Prevalence characteristics of cervical human papillomavirus infection in Chengdu and Aba District, Sichuan Province, China
Authors: Wang Qianqian , Xu Min , Zhou Hua , Li Yahui , Ma Jichun , Zhu Xuan , He Weijun 
Published: June 2024

Purpose
The genotype distribution of human papillomavirus (HPV) infection varies greatly in different regions. This study aims to determine the prevalence and type-specific distribution of HPV among females from Chengdu and Aba in Sichuan Province, which differ in geographical location, economic status, and living habits. These can serve as evidence of epidemic patterns for future design and implementation of vaccination and screening programs.

Methods
A retrospective cross-sectional study was conducted on 144 113 women who underwent cervical screening at Chengdu Women’s and Children’s Central Hospital from January 2015 to September 2020. Meanwhile, 1799 samples from February 2018 to December 2021 were collected from Aba Maternal and Child Health Hospital. HPV DNA genotype testing was performed using real‐time PCR. The overall prevalence, annual trend, age-specific prevalence, and type distribution were analyzed.

Results
The overall HPV prevalence was 22.51% in Chengdu. During 2015–2020, the highest prevalence rate was observed in 2018. Age-specific HPV distribution displayed a bimodal distribution among women aged ≤25 or ≥46 years old. The top three prevalent genotypes were HPV52, -16, and -58. Although the total prevalence of HPV in Aba was 14.23%, there was an upward trend from 2018 to 2021. However, no significant differences were identified in HPV infection rate across all age groups. HPV52, -53, and -16 were the major genotypes. Furthermore, single-type HPV infections and high-risk HPV infections were identified as the most common infection types in both regions.

Conclusion
Our findings demonstrate the overall prevalence of HPV was still high in Chengdu and Aba. The age-specific prevalence distribution demonstrated different patterns. Non-vaccine-covered HR-HPV53, -51and LR-HPV81, -CP8304 were frequently detected, which was worth significant clinical attention. In summary, regional HPV screening provides valuable clinical guidance for cervical cancer prevention and vaccine selection in Western China.
Double burden of malnutrition among women of reproductive age: Trends and determinants over the last 15 years in India
Authors: Prithishkumar Ivan James , Sappani Marimuthu , Ranjan Varsha , Garg Chhavi , Mani Thenmozhi , Babu Malavika , Joy Melvin , Rao Bhawna , Asirvatham Edwin Sam , Lakshmanan Jeyaseelan 
Published: June 2024

Introduction
Double burden of malnutrition (DBM) has been recognized by the World Health Organisation (WHO) as an emerging Global Syndemic characterized by the simultaneous occurrence of both undernutrition and overnutrition. Women of the reproductive age group (15 to 49 years) are disproportionately affected by DBM and are at high risk of continuing the intergenerational cycle of malnutrition. This study aims to assess the changing trends and determinants of DBM among women of the reproductive age group in India.

Materials and methods
We used data from three rounds of National Family Health Surveys (NFHS-3,4,5) conducted in years 2005–06, 2015–16, and 2019–2021. Descriptive statistics and Poisson regression analysis were done using weights with log link function.

Results
The prevalence of anaemia, underweight and overweight/obesity was 57.2%, 18.6% and 24% respectively. The combined burden of underweight and anaemia has declined by 46% (21.6% to 11.7%), whereas the combined burden of overweight/obesity and anaemia has increased by 130% (5.4% to 12.4%) in the past 15 years. The prevalence of DBM, which includes both underweight and overweight/obesity with anaemia was 24.1% in 2021, a decline of 11% in 15 years. Women who were younger, rural, less educated, poor and middle class, and women living in the eastern, western and southern regions of India had higher risk for being underweight with anaemia and lower risk for developing overweight/obesity with anaemia.

Conclusion
The significant decrease in underweight yet enormous increase in overweight/obesity over the past 15 years with the persistence of anaemia in both ends of the nutritional spectrum is characteristic of the new nutritional reality emphasizing the need to address malnutrition in all its forms. It is critical to consider geography and a population specific, double-duty targeted intervention to holistically address the risk factors associated with DBM and accomplish India’s commitment to the global agenda of Sustainable Development Goals-2030.
Effect of implementing of the IDEAL discharge model on satisfaction of patient referred to trauma emergency department
Authors: Moradi Rekabdar Kalaiee Zahra , Ghafouri Raziyeh , Zandi Mitra , Nasiri Malihe 
Published: June 2024

Background
Patient education at the time of discharge is one of the most important challenges in the emergency department. This study aimed to evaluate the Effect of implementing the IDEAL, or integrated discharge model, on the satisfaction of patients referred to the trauma emergency department.

Methods
This quasi-experimental study was conducted on the patients referred to the trauma emergency department of Imam Hossein Hospital in Tehran. Eighty-six patients were recruited from January 20, 2023, until July 30, 2023. In the intervention group, the educational content was taught using the IDEAL (Inclusion, Discussion, Education, Assessment, Listening) or integrated discharge model, and in the control group, it was taught using the emergency department routine method. The satisfaction questionnaire of the emergency department was completed before and after the education in both groups and compared between the two groups. The data were analyzed by using SPSS (version 20) software.

Results
The results showed that out of the 86 participating patients, 52 (60.5%) were male and 34 (39.5%), with a mean (Standard Deviation) of 39.14 (10.89) years old. Demographic characteristics were homogeneous between the two groups (P > 0.05). The mean (standard deviation) of satisfaction of the participants after education, totally was 63.56 (16.21), in the intervention group it was 77.37 (7.95), and in the Control group it was 49.74 (8.84). The mean (SD) participants satisfaction on arrival at the emergency department in the intervention group was 19.16 (2.75) and in the control group was 13.51 (2.51), during hospitalization in the intervention group was 10.72 (1.77) and in the Control group 6.74 (1.81), discharge time in the intervention group 14.51 (2.93) and in the control group 2.93 (2.04), Overall satisfaction with nursing care in intervention group 13.85 (2.46) and in the control group 8.46 (2.41), Overall satisfaction with medical procedures in the intervention group 12.81 (2.73) and in the control group 8.58 (3.20) and Overall patient satisfaction in the intervention group 2.27 (1.81) and 41.4 (1.66) in the control group. An independent T-test was used to compare satisfaction and its dimensions in two groups, and there was a statistically significant difference between the two groups (P<0.01).

Conclusion
The study results showed a statistically significant difference in the satisfaction in the intervention and control groups, so it can be concluded that conducting the integrated discharge model is effective in increasing the satisfaction of trauma patients. Therefore, it is recommended to use this educational method to increase patient satisfaction and decrease readmission rates.
The Journalist’s Predicament: Difficult Choices in a Declining Profession, Matthew Powers and Sandra Vera-Zambrano (2023)
Authors: Giotis Chrisanthi 
Published: June 2024

Review of: The Journalist’s Predicament: Difficult Choices in a Declining Profession, Matthew Powers and Sandra Vera-Zambrano (2023)
New York: Columbia University Press, 320 pp.,
ISBN 978-0-23120-791-1, p/bk, USD 35
ISBN 978-0-23120-790-4, h/bk, USD 140
ISBN 978-0-23155-717-7, e-book, USD 34.99
Constructive Journalism: Precedents, Principles and Practices, Peter Bro (2024)
Authors: Sparrow Jeff 
Published: June 2024

Review of: Constructive Journalism: Precedents, Principles and Practices, Peter Bro (2024)
Routledge: Focus Books, 108 pp.,
ISBN 978-1-03251-609-7, h/bk, AUD 77.25
ISBN 978-1-00340-309-8, e-book, AUD 26.99
Violence against Women in the Global South: Reporting in the #MeToo Era, Andrea Jean Baker, Celeste González de Bustamante and Jeannine E. Relly (eds) (2023)
Authors: Gleave Josie 
Published: June 2024

Review of: Violence against Women in the Global South: Reporting in the #MeToo Era, Andrea Jean Baker, Celeste González de Bustamante and Jeannine E. Relly (eds) (2023)
Cham: Palgrave Macmillan, 259 pp.,
ISBN 978-3-03130-910-6, h/bk, EUR 129.99
ISBN 978-3-03130-911-3, e-book, EUR 106.99
Os movimentos indígenas na Abya Yala:
Authors: Costa César Augusto , Xavier Fernanda Ollé 
Published: June 2024

Este artigo tem por objetivo evidenciar os movimentos indígenas a partir do marco histórico e societário no Brasil, e por isto, inscritos no rol das suas minorias identitárias ao qual possuem uma relação vital com o território onde vivem, estabelecendo com ele territorialidades fundamentais. Para tanto alcançar esse fim, realizamos uma pesquisa bibliográfica, mediante uma abordagem social crítica à luz de autores/as como Enrique Dussel, Ivone Lixa e Débora Ferrazo, Carlos Walter Porto-Gonçalves, Anibal Quijano, Sáskia Sassen entre outros/as, e das Constituições Federais do Brasil (1988), da Bolívia (2009) e do Equador (2008), respectivamente. As temáticas debatidas permeiam os direitos humanos e a territorialidade dos povos indígenas das Américas, sob um contexto de violências e atos de exclusão operados pelo sistema-mundo moderno-colonial por intermédio de um Estado orientado por essa matriz colonial eurocêntrica. O texto promoveu reflexões no sentido da necessidade de uma crítica latino-americana acerca do Estado brasileiro, ao qual julgamos necessário firmarmos no reconhecimento da autonomia indígena e dos direitos da natureza, dentre outros, como direitos a garantir a estes povos o exercício de suas territorialidades ao encontro de suas identidades étnicas.
Biochar-Based Subsurface-Flow Wetland from Crumb Rubber Scrap in Treatment of Landfill Leachate
Authors: Riyanti Anggrika , Hadrah Hadrah , Kasman Monik , Ramadan Bimastyaji Surya , Saputra Iwan , Fitri Riska Rahmah Dani 
Published: June 2024

Leachate resulting from the decomposition of organic waste is still a challenging problem, especially in landfill management. Constructed wetlands (CW) are effective, economical, and environmentally friendly options to treat landfill leachate. Biochar added into CW as a pollutant adsorbent in leachate treatment. This study aimed to determine the effectiveness of sub-surface flow CW amended with biochar in reducing leachate pollutants. Biochar was synthesized from crumb rubber scrap waste using pyrolysis. The variation biochar in CW i.e. CW0 without biochar as a control system, CW1 10% biochar, CW2 20% biochar, and CW3 30% biochar. Leachate samples flowed into each CW reactor for 10 days of retention time. The scanning electron showed that the biochar pores ranged from 5-10 կm, containing elements of C, O, Ca, N, Mg, Al, Si, and Fe. Some elements have greater cumulative mass and atomic percentage values i.e. C 34.51%, O 26.54%, and Ca 21.85%. The result of CW treatment showed that the CW system was able to remove 76-88% BOD5, 70-87% COD, and 67-81% TSS. The addition of biochar in CW increased pollutant removal by 7-14%, showing that biochar is able to increase pollutant adsorption in wastewater and improve CW performance. Furthermore, converting organic waste into biochar is highly recommended as a sustainable way to generate useful resources.
Identification of a novel drug target in Porphyromonas gingivalis by a computational genome analysis approach
Authors: Alqurashi Abdulmajeed , Ahmad Waqar , Rahman Ziaur , Nawab Javed , Siddiqui Muhammad Faisal , Akbar Ali , Alkraiem Ayman Ahmad , Latif Muhammad 
Published: June 2024

Abstract
This study applied a subtractive genomics approach to identify a potential drug target in the Porphyromonas gingivalis strain (ATCC BAA-308/W83). The aim was to characterize the whole proteome and hypothetical proteins (HPs) through structural, functional, and pathway predictions. The proteome was systematically reduced to identify essential proteins (EPs), non-homologous proteins (NHPs), and non-paralogous proteins (NPPs) while excluding those that were similar to the human proteome. Out of 1,836 proteins, the cluster database at high identity with tolerance algorithm identified 36 sequences as paralogous, having 80% identity. The resulting 1,827 proteins were compared to the human proteome using BLASTp (e-value 10−3), resulting in 1,427 NHPs. These were then aligned with the DEG database using BLASTp (e-value of 10−5), identifying 396 NHPs essential for pathogen survival. CELLO predicted the sub-cellular localization, and KEGG Automated Annotation Server identified potential metabolic pathways using a BLASTp similarity search of NHPs and EPs against the infrequently updated KEGG database. A total of 79 HPs essential for P. gingivalis were selected, and their molecular weights were determined. HPs were screened for metabolic pathway prediction, and the 3D structures of the proposed HPs were determined using homology modeling, and validation was performed. Only one HP (putative arginine deiminase) was qualified and found to be involved in the arginine and proline metabolic pathway.