bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics and preventability of medication-related admissions for acute kidney injury and dehydration in elderly patients
Authors: Coppes Tristan , Hazen Ankie C. M. , Zwart Dorien L. M. , Koster Ellen S. , van Gelder Teun , Bouvy Marcel L. 
Published: June 2024

Abstract
Purpose
Patients with impaired renal function using medication that affects glomerular filtration rate are at increased risk of developing acute kidney injury (AKI) leading to hospital admissions. The risk increases during periods of dehydration due to diarrhoea, vomiting or fever (so-called “sick days”), or high environmental temperatures (heat wave). This study aims to gain insight into the characteristics and preventability of medication-related admissions for AKI and dehydration in elderly patients.

Methods
Retrospective case series study in patients aged ≥ 65 years with admission for acute kidney injury, dehydration or electrolyte imbalance related to dehydration that was defined as medication-related. General practitioner’s (GP) patient records including medication history and hospital discharge letters were available. For each admission, patient and admission characteristics were collected to review the patient journey. A case-by-case assessment of preventability of hospital admissions was performed.

Results
In total, 75 admissions were included. Most prevalent comorbidities were hypertension, diabetes, and known impaired renal function. Diuretics and RAS-inhibitors were the most prevalent medication combination. Eighty percent of patients experienced non-acute onset of symptoms and 60% had contacted their GP within 2 weeks prior to admission. Around 40% (n = 29) of admissions were considered potentially preventable if pharmacotherapy had been timely and adequately adjusted.

Conclusion
A substantial proportion of patients admitted with AKI or dehydration experience non-acute onset of symptoms and had contacted their GP within 2 weeks prior to admission. Timely adjusting of medication in these patients could have potentially prevented a considerable number of admissions.
Shaping the Microbial Landscape: Parasitoid-Driven Modifications of Bactrocera dorsalis Microbiota
Authors: Gwokyalya Rehemah , Herren Jeremy K. , Weldon Christopher W. , Ndlela Shepard , Gichuhi Joseph , Ongeso Nehemiah , Wairimu Anne W. , Ekesi Sunday , Mohamed Samira A. 
Published: June 2024

AbstractKoinobiont endoparasitoids regulate the physiology of their hosts through altering host immuno-metabolic responses, processes which function in tandem to shape the composition of the microbiota of these hosts. Here, we employed 16S rRNA and ITS amplicon sequencing to investigate whether parasitization by the parasitoid wasps, Diachasmimorpha longicaudata (Ashmaed) (Hymenoptera: Braconidae) and Psyttalia cosyrae (Wilkinson) (Hymenoptera: Braconidae), induces gut dysbiosis and differentially alter the gut microbial (bacteria and fungi) communities of an important horticultural pest, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae). We further investigated the composition of bacterial communities of adult D. longicaudata and P. cosyrae to ascertain whether the adult parasitoids and parasitized host larvae share microbial taxa through transmission. We demonstrated that parasitism by D. longicaudata induced significant gut perturbations, resulting in the colonization and increased relative abundance of pathogenic gut bacteria. Some pathogenic bacteria like Stenotrophomonas and Morganella were detected in both the guts of D. longicaudata-parasitized B. dorsalis larvae and adult D. longicaudata wasps, suggesting a horizontal transfer of microbes from the parasitoid to the host. The bacterial community of P. cosyrae adult wasps was dominated by Arsenophonus nasoniae, whereas that of D. longicaudata adults was dominated by Paucibater spp. and Pseudomonas spp. Parasitization by either parasitoid wasp was associated with an overall reduction in fungal diversity and evenness. These findings indicate that unlike P. cosyrae which is avirulent to B. dorsalis, parasitization by D. longicaudata induces shifts in the gut bacteriome of B. dorsalis larvae to a pathobiont-dominated community. This mechanism possibly enhances its virulence against the pest, further supporting its candidacy as an effective biocontrol agent of this frugivorous tephritid fruit fly pest.
Digitalisierung und Sorgebeziehungen von Alleinlebenden im Alter: eine kritische Analyse politischer Dokumente
Authors: Werny Rafaela , Reich Marie , Leontowitsch Miranda , Oswald Frank 
Published: June 2024

ZusammenfassungDie Digitalisierung aller Lebensbereiche transformiert das gesellschaftliche und soziale Miteinander. Es entstehen neue kulturelle Vorstellungen von Sorgebeziehungen, die ältere Menschen vor Herausforderungen stellen können. Diese gelten insbesondere für Alleinlebende im Alter, die seltener digitale Geräte benutzen und bei der Bewältigung von zunehmend digitalisierten Aufgaben (Termine, Buchungen, finanzielle Angelegenheiten) auf Unterstützung angewiesen sind. Der vorliegende Artikel untersucht das Verhältnis von Digitalisierung und Sorgebeziehungen von alleinlebenden älteren Menschen mithilfe einer kritischen Dokumentenanalyse nach Bacchi. Dieses Vorgehen ermöglicht es, das Verständnis hinter den Begriffen Alleinleben, Sorgebeziehungen und Digitalisierung in Bezug auf ältere Menschen einzeln und im Zusammenspiel in den Blick zu nehmen sowie Leerstellen sichtbar zu machen. Die Analyse von Sozialgesetzgebung und politischen sowie zivilgesellschaftlichen Dokumenten führt zu zwei zentralen Ergebnissen: Zum einen wird eine individuelle Verantwortungszuschreibung im Hinblick auf die Versorgung sowie den Zugang und Umgang mit Digitalisierung an ältere Menschen und ihre Beziehungsnetzwerke deutlich. Diese Individualisierung erscheint besonders signifikant, da die Digitalisierung als Lösungsansatz für gesamtgesellschaftliche Probleme, wie den demografischen Wandel oder den Pflegekräftemangel, präsentiert wird. Zum anderen zeigt die Analyse, dass in den Dokumenten, die Handlungsrahmen schaffen, Digitalisierung im Alter nicht thematisiert wird. Diese fehlende Fokussierung hat zur Folge, dass Handlungsstrategien schwach ausfallen.
Transvaginal versus transabdominal specimen extraction in minimally invasive surgery: a systematic review and meta-analysis
Authors: Chang Jasmine Hui Er , Xu Hongyun , Zhao Yun , Wee Ian Jun Yan , Ang Joella Xiaohong , Tan Emile Kwong-Wei , Seow-En Isaac 
Published: June 2024

Abstract
Aim
Natural orifice specimen extraction (NOSE) is an alternative to conventional transabdominal retrieval. We aimed to compare outcomes following transvaginal specimen extraction (TVSE) and transabdominal specimen extraction (TASE) in minimally invasive abdominal surgery.

Methods
An electronic database search of PubMed, Embase and CENTRAL was performed from inception until March 2023. Comparative studies evaluating TVSE versus TASE in adult female patients were included. Studies involving transanal NOSE, endoluminal surgery, or TVSE with concomitant hysterectomy were excluded. Weighted mean differences (WMD) and odds ratio were estimated for continuous and dichotomous outcomes respectively. Primary outcomes were postoperative day 1 (POD1) pain and length of stay (LOS). Secondary outcomes were operative time, rescue analgesia, morbidity, and cosmesis. A review of sexual, oncological, and technical outcomes was performed.

Results
Thirteen studies (2 randomised trials, 11 retrospective cohort studies), involving 1094 patients (TASE 583, TVSE 511), were included in the analysis. Seven studies involved colorectal disease and six assessed gynaecological conditions. TVSE resulted in significantly decreased POD1 pain (WMD 1.08, 95% CI: 0.49, 1.68) and shorter LOS (WMD 1.18 days, 95% CI: 0.14, 2.22), compared to TASE. Operative time was similar between both groups, with fewer patients requiring postoperative rescue analgesia with TVSE. Overall morbidity rates, as well as both wound-related and non-wound related complication rates were better with TVSE, while anastomotic morbidity rates were comparable. Cosmetic scores were higher with TVSE. TVSE did not result in worse sexual or oncological outcomes.

Conclusion
TVSE may be feasible and beneficial compared to TASE when performed by proficient laparoscopic operators, using appropriate selection criteria. Continued evaluation with prospective studies is warranted.
A needs-based perspective on long-term care, obesity, and old age
Authors: Hansen Solveig Lena , Preuß Benedikt , Frisina Doetter Lorraine 
Published: June 2024

Abstract
Definition of the problem
Obesity is a burgeoning challenge for healthcare systems worldwide. In times of demographic change, it also affects an increasing number of older persons, presenting substantial challenges to delivering health and nursing care in both acute and long-term care (LTC) settings. So far, a detailed analysis of the diverse group of 65+ in this field is missing, particularly in the area of LTC. The needs of neither care recipients, nor those of nurses and institutions are monitored, analyzed, or systematically evaluated. Moreover, ethical implications of professional care for older persons with obesity have not yet been discussed in research and policy.

Arguments
We argue that a needs-based approach is appropriate to address these ethical complexities. We further argue that a comprehensive mapping of the ethical terrain is best from an interdisciplinary and mixed methods perspective. For this, we conduct a scoping review to synthesize the state-of-the-art in both the healthcare and LTC settings; and we focus on challenges reported in case studies from professional care settings in European and North American institutions.

Conclusion
Our findings point to a lack of research on ethical issues related to the LTC needs of older persons living with obesity and the challenges faced by their professional carers. From the limited number of (case) studies that can be found, however, a series of ethical concerns emerge that have direct import for access, utilization, and quality of care. Accordingly, a new research agenda is needed to inform an ethical approach for policy and practice. It must be rooted in a concern for both care recipients and caregivers in mixed methods studies. Future research should provide criteria for balancing needs, allocating resources and developing practical solutions for people who are confronted with multiple stigma.
Nachhaltiger Lebensmittelkonsum – Erklärungsansätze für den Attitude-Behavior-Gap von Studierenden in Norddeutschland
Authors: Kruse Hauke 
Published: June 2024

ZusammenfassungDer Lebensmittelsektor gilt als ein Haupttreiber für globale Umweltveränderungen. Um nachhaltige Entwicklung zu gewährleisten, sind radikale Veränderungen sowohl in Nahrungsmittelproduktion als auch im Konsumverhalten der Verbraucher:innen unumgänglich. Trotz steigenden Umweltbewusstseins gibt es jedoch Diskrepanzen zwischen positiven Einstellungen zum nachhaltigen Lebensmittelkonsum und dem tatsächlichem Konsumverhalten. Diese Studie untersucht den sogenannten Attitude-Behavior-Gap für die Zielgruppe junger Student:innen aus urbanen und ländlichen Regionen. Mithilfe von zwölf Interviews werden potenzielle Erklärungsansätze erforscht und Maßnahmen skizziert, die dazu beitragen können, die Diskrepanzen abzubauen. Als Hauptbarrieren konnten zusätzlicher Aufwand und vermeintlich höhere Preise nachhaltiger Lebensmittel identifiziert werden. Darüber hinaus stellen fehlende Zugänglichkeiten zu nachhaltigen Lebensmitteln eine Hürde für Studierende aus ländlichen Regionen dar. Die Studie zeigt, dass der Wunsch nach nachhaltigem Konsum die Studierenden vor äußerst komplexe Entscheidungen stellt, die häufig Zielkonflikte aufzeigen und zu Entscheidungen führen, die von den Befragten selbst als nicht optimal betrachtet werden. Für den Abbau der Diskrepanzen sind Maßnahmen auf verschiedenen Ebenen erforderlich. Politisch müssen Rahmenbedingungen geschaffen werden, die nachhaltigen Lebensmittelkonsum erleichtern. Unternehmen und Einzelhändler sollten transparente Informationen bereitstellen und ihr Sortiment nachhaltiger gestalten. Darüber hinaus ist es grundlegend, dass Verbraucher:innen einen zusätzlichen individuellen Aufwand in Kauf nehmen.
Does obesity and varying body mass index affect the clinical outcomes and safety of biportal endoscopic lumbar decompression? A comparative cohort study
Authors: Olson Thomas E. , Upfill-Brown Alexander , Adejuyigbe Babapelumi , Bhatia Nitin , Lee Yu-Po , Hashmi Sohaib , Wu Hao-Hua , Bow Hansen , Park Cheol Wung , Heo Dong Hwa , Park Don Young 
Published: June 2024

Abstract

Background
Endoscopic spine surgery has recently grown in popularity due to the potential benefits of reduced pain and faster recovery time as compared to open surgery. Biportal spinal endoscopy has been successfully applied to lumbar disc herniations and lumbar spinal stenosis. Obesity is associated with increased risk of complications in spine surgery. Few prior studies have investigated the impact of obesity and associated medical comorbidities with biportal spinal endoscopy.

Methods
This study was a prospectively collected, retrospectively analyzed comparative cohort design. Patients were divided into cohorts of normal body weight (Bone Mass Index (BMI)18.0–24.9), overweight (BMI 25.0–29.9) and obese (BMI > 30.0) as defined by the World Health Organization (WHO). Patients underwent biportal spinal endoscopy by a single surgeon at a single institution for treatment of lumbar disc herniations and lumbar spinal stenosis. Demographic data, surgical complications, and patient-reported outcomes were analyzed. Statistics were calculated amongst treatment groups using analysis of variance and chi square where appropriate. Statistical significance was determined as p < 0.05.

Results
Eighty-four patients were followed. 26 (30.1%) were normal BMI, 35 (41.7%) were overweight and 23 (27.4%) were obese. Patients with increasing BMI had correspondingly greater American Society of Anesthesiologist (ASA) scores. There were no significant differences in VAS Back, VAS Leg, and ODI scores, or postoperative complications among the cohorts. There were no cases of surgical site infections in the cohort. All cohorts demonstrated significant improvement up to 1 year postoperatively.

Conclusions
This study demonstrates that obesity is not a risk factor for increased perioperative complications with biportal spinal endoscopy and has similar clinical outcomes and safety profile as compared to patients with normal BMI. Biportal spinal endoscopy is a promising alternative to traditional techniques to treat common lumbar pathology.
The Use of Hydrochemical Zoning to Predict Water Hazards: The Example of the Olkusz-Pomorzany Zn-Pb Mine
Authors: Motyka Jacek , Cień Damian , d‘Obyrn Kajetan 
Published: June 2024

AbstractA water hazard is one of the greatest dangers in mining and tunneling operations and the issue of predicting water hazard zones has been extensively discussed in the literature. However, the currently used methods require a highly detailed understanding of hydrogeological conditions or have major limitations and often produce unreliable results. This paper describes the use of hydrogeochemical anomalies as an indicator of impending mine water hazard zones. The proposed method uses the concentration of Cl ions in water extracts from Permian rock samples collected from the face of the mine workings. The concentration of Cl ions in the water extracts strongly correlated with the concentration of this ion in the pore solutions extracted from the same rock samples. Additionally, the concentration of Cl ions in the pore solutions exhibited a very strong correlation with the concentration from the Permian leaks. Thus, the decreasing concentration of Cl ions in the water extracts was deemed a reliable signal of an approaching water hazard zone. In the hydrogeological conditions present in the Olkusz-Pomorzany mine, this method enabled the detection of the moment when a water hazard zone was ≈ 200–250 m away.
Relative dispersion and relative diffusivities in an ocean-wave coupled model of the North Sea
Authors: Villa Castrillón Luciana , Ricker Marcel , Staneva Joanna , Meyerjürgens Jens , Badewien Thomas H. , Stanev Emil V. 
Published: June 2024

AbstractThe study analyzes the impact of various wave-induced processes on relative dispersion and diffusivities in the North Sea using OpenDrift, a Lagrangian particle-drift model driven by a fully coupled NEMO-WAM model. The coupled model parameterizations include sea state-dependent momentum flux, energy flux, and wave-induced mixing. The study demonstrates that Eulerian currents, influenced by the interaction between the ocean and wave models, significantly enhance particle transport. Experiments conducted using drifter clusters obtained during an RV Heincke excursion further confirm the impact of wind-wave coupling. The analysis includes a comparison of results from experiments with and without wave coupling. The impact of diffusion in the Lagrangian model on relative dispersion is investigated, with the conclusion that diffusion is essential for achieving precise simulations. Furthermore, the incorporation of wind-wave-driven mixing parameters, including sea state-dependent momentum flux, energy flux, and wave-induced mixing, into the hydrodynamic model leads to elevated levels of relative dispersion and diffusivity.
Future perspectives of Brazilian beef production: what is the role of Silvopastoral systems?
Authors: Agethen Katrin , Mauricio Rogerio Martins , Deblitz Claus , Izquierdo Maria Dolores , Reyes Ernesto , Chará Julian 
Published: June 2024

AbstractAgainst the backdrop of changing production conditions and market requirements, it seems time has come to rethink Brazil’s beef production systems. We analyse the economic and environmental performance of three beef production systems: classic beef production system (CB), and two types of silvopastoral systems: the integrated crop-livestock-forestry system (ICLFS) and the natural regeneration system (NR) in a comparative case study analysis. We find that, though costs of production are the lowest for CB, only the ICLFS and NR case studies are generating long-term profits. While greenhouse gas emissions per kg live weight added are lowest in ICLFS, followed by NR and CB, per hectare (ha) emissions are highest in NR, followed by ICLFS and CB. Considering the system’s carbon removal, NR and potentially ICLFS are sequestering more than releasing. Additionally, the land required to produce beef is lowest in NR, followed by ICLFS and CB. Considering the additional outputs produced by ICLFS and NR, they showcase the potential of multifunctional production systems for future scenarios, where land scarcity puts land-demanding production systems, such as beef, under pressure. The three production systems perform differently depending on the indicators analysed. How they will reply to future challenges depends on the location and the specific environment. Yet, from the analysed systems, CB is the least sustainable, economically and environmentally.
The Other Side: Preschool Children’s Experience of a Read-Aloud Focused on Social Justice
Authors: Wild Norline R. 
Published: June 2024

AbstractThe purpose of this article is to detail preschool age students’ exploration of social justice as they cocreated with their teacher an interactive read-aloud approach, named Picturebooks for Social Justice. Over the three phases, the teacher researcher studied her own preschool teaching as she read and explored 12 picturebooks with the 3-5-year-old children in her preschool class. Guided by relational and critical theoretical perspectives, findings demonstrate and detail examples of the children’s learning across the social justice standards of identity, diversity, justice, and action. These standards, which functioned both as the content and the goals of Picturebooks for Social Justice, were explored through books in the context of the strong bond between the children and teacher. The insights gained in this study can guide educators and researchers in understanding young children’s capacity to explore and understand social justice.
Performance and investment styles of international multi-asset funds during market crises
Authors: Leite Paulo 
Published: June 2024

AbstractThis paper presents a comprehensive investigation into the performance of multi-asset funds investing internationally. Based on a custom-built conditional multi-factor model, which includes several bond and equity-related factors, along with time-varying betas and alphas, we show that funds in our dataset significantly underperform from 2004 to 2021. This evidence holds even on a before-fee basis, with funds investing predominantly in bonds exhibiting significantly higher alphas than funds investing predominantly in equities. Since multi-asset funds may better hedge against market downturns than equity or bond funds, given their higher asset class diversification, we also evaluate performance for crisis and non-crisis phases separately. The results show that, during market crises, international multi-asset funds perform significantly better than in non-crisis times, achieving neutral performance. However, while funds that favour bond investments perform similarly across different market phases, funds that prioritize equity investments perform significantly better during crises. Consequently, multi-asset funds with higher bond holdings can be a better option during non-crisis periods, while funds with higher equity holdings should be preferred during market downturns. This somewhat puzzling finding seems to be related to funds’ cash holdings. By providing a better understanding of the asset allocation decisions of international mutual fund managers, as well as of their impact on fund performance, this work has meaningful implications for investors.