bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dissolving the mystery of subsurface controls on snowmelt–discharge dynamics in karst mountain watersheds using hydrologic timeseries
Authors: Thurber Daniel , Lane Belize , Xu Tianfang , Neilson Bethany T. 
Published: May 2024

AbstractStreamflow generation in mountain watersheds is strongly influenced by snow accumulation and melt as well as groundwater connectivity. In mountainous regions with limestone and dolomite geology, bedrock formations can host karst aquifers, which play a significant role in snowmelt–discharge dynamics. However, mapping complex karst features and the resulting surface‐groundwater exchanges at large scales remains infeasible. In this study, timeseries analysis of continuous discharge and specific conductance measurements were combined with gridded snowmelt predictions to characterize seasonal streamflow response and evaluate dominant watershed controls across 12 monitoring sites in a karstified 554 km2 watershed in northern Utah, USA. Immense surface water hydrologic variability across subcatchments, years and seasons was linked to geologic controls on groundwater dynamics. Unlike many mountain watersheds, the variability between subcatchments could not be well described by typical watershed properties, including elevation or surficial geology. To fill this gap, a conceptual framework was proposed to characterize subsurface controls on snowmelt–discharge dynamics in karst mountain watersheds in terms of conduit flow direction, aquifer storage capacity and connectivity. This framework requires only readily measured surface water and climatic data from nested monitoring sites and was applied to the study watershed to demonstrate its applicability for evaluating dominant controls and climate sensitivity.
Clinical research on neurological and psychiatric diagnosis and monitoring using wearable devices: A literature review
Authors: Huang Jielin , Wang Huidi , Wu Qiheng , Yin Jia , Zhou Hongwei , He Yan 
Published: May 2024

AbstractWearable devices have opened up exciting possibilities for monitoring and managing home health, particularly in the realm of neurological and psychiatric diseases. These devices capture signals related to physiological and behavioral changes, including heart rate, sleep patterns, and motor functions. Their emergence has resulted in significant advancements in the management of such conditions. Traditional clinical diagnosis and assessment methods heavily rely on patient reports and evaluations conducted by healthcare professionals, often leading to a detachment of patients from their home environment and creating additional burdens for both patients and healthcare providers. The increasing popularity of wearable devices offers a potential solution to these challenges. This review focuses on the clinical utility of wearable devices in diagnosing and monitoring neurological and psychiatric diseases. Through research findings and practical examples, we highlight the potential role of wearable devices in diagnosing and monitoring conditions such as autism spectrum disorder, depression, epilepsy, stroke prognosis, Parkinson's disease, dementia, and other diseases. Additionally, the review discusses the benefits and limitations of wearable devices in clinical applications, while highlighting the challenges they face. Finally, it provides prospects for enhancing the value of wearable devices in the monitoring and diagnosis of neurological and psychiatric diseases.
Hepatotoxicity of titanium dioxide nanoparticles
Authors: Khan Jangrez , Kim Nicholas D. , Bromhead Collette , Truman Penelope , Kruger Marlena C. , Mallard Beth L. 
Published: May 2024

AbstractThe food additive E171 (titanium dioxide, TiO2), is widely used in foods, pharmaceuticals and cosmetics. It is a fine white powder, with at least one third of its particles sized in the nanoparticulate (˂100 nm range, TiO2 NPs). The use of E171 is controversial as its relevant risk assessment has never been satisfactorily accomplished. In vitro and in vivo studies have shown dose‐dependent toxicity in various organs including the liver. TiO2 NPs have been shown to induce inflammation, cell death and structural and functional changes within the liver. The toxicity of TiO2 NPs in experimental models varies between organs and according to their physiochemical characteristics and parameters such as dosage and route of administration. Among these factors, ingestion is the most significant exposure route, and the liver is a key target organ. The aim of this review is to highlight the reported adverse effects of orally administered TiO2 NPs on the liver and to discuss the controversial state of its toxicity.
In vitro proliferation and differentiation of mouse spermatogonial stem cells in decellularized human placenta matrix
Authors: Asgari Fatemeh , Asgari Hamidreza , Najafi Mohammad , Hajiaghalou Samira , Pirhajati‐Mahabadi Vahid , Mohammadi Amirhossein , Gholipourmalekabadi Mazaher , Koruji Morteza 
Published: May 2024

AbstractUtilizing natural scaffold production derived from extracellular matrix components presents a promising strategy for advancing in vitro spermatogenesis. In this study, we employed decellularized human placental tissue as a scaffold, upon which neonatal mouse spermatogonial cells (SCs) were cultured three‐dimensional (3D) configuration. To assess cellular proliferation, we examined the expression of key markers (Id4 and Gfrα1) at both 1 and 14 days into the culture. Our quantitative reverse transcription‐polymerase chain reaction (qRT‐PCR) analysis revealed a notable increase in Gfrα1 gene expression, with the 3D culture group exhibiting the highest levels. Furthermore, the relative frequency of Gfrα1‐positive cells significantly rose from 38.1% in isolated SCs to 46.13% and 76.93% in the two‐dimensional (2D) and 3D culture systems, respectively. Moving forward to days 14 and 35 of the culture period, we evaluated the expression of differentiating markers (Sycp3, acrosin, and Protamine 1). Sycp3 and Prm1 gene expression levels were upregulated in both 2D and 3D cultures, with the 3D group displaying the highest expression. Additionally, acrosin gene expression increased notably within the 3D culture. Notably, at the 35‐day mark, the percentage of Prm1‐positive cells in the 3D group (36.4%) significantly surpassed that in the 2D group (10.96%). This study suggests that the utilization of placental scaffolds holds significant promise as a bio‐scaffold for enhancing mouse in vitro spermatogenesis.
Diagnostic value of imaging in patients with clear cell papillary renal cell carcinoma: A case series and literature review
Authors: Song Yuxuan , Yang Ran , Zhang Xiujuan , Shi Jiahong , Pan Qizheng 
Published: May 2024

AbstractClear cell papillary renal cell carcinoma (CCPRCC) is a newly classified renal cell carcinoma with a low degree of malignancy. Its imaging features have not been studied deeply. Therefore, we reviewed the imaging features of CCPRCC. Solid CCPRCC shows high echo or isoecho mass on conventional ultrasound. Contrast enhanced ultrasound shows “fast forward and slow backward, uneven high enhancement”. Computed tomography shows high enhancement and maximum enhancement in the cortical‐medullary phase. Magnetic resonance imaging shows slightly low T1WI and high T2WI. This article aims to improve the understanding of CCPRCC by clinical radiologists and promote the accurate.
Self‐directed learning in dental hygiene students: Impact of locus of control and personality traits
Authors: Machakos Teresa , Boyd Linda D. , Oh Uhlee , Vineyard Jared 
Published: May 2024

AbstractObjectivesThe purpose of this study was to identify demographic variables, the level of self‐directed learning (SDL), locus of control (LOC), and personality traits in dental hygiene (DH) students and to identify predictive variables for SDL.MethodsCross‐sectional survey research was conducted with a convenience sample of DH students (n = 229) in the United States using a web‐based survey. The validated instruments used were the Self‐Directed Learning Instrument (SDLI) to determine level of SDL, the Academic Locus of Control (ALC) scale for college students to evaluate LOC, and the Big Five Inventory‐2‐Extra Short Form (BFI‐2‐XS) to identify personality traits. Descriptive, correlation, and regression analyses were performed.ResultsThe completion rate was 68.9% (n = 159). The average SDLI score of the sample was 82.59, indicating a high overall level of SDL. The average ALC score was 10.34, indicating an overall internal LOC. Internal LOC (B = −0.319, SE = 0.082, β = ‐0.330, p < 0.001) and an open‐minded personality trait (B = 1.156, SE = 0.363, β = 0.233, p = 0.002) emerged as significant predictors of learning motivation (B = −0.138, SE = 0.057, β = −0.214, p < 0.017) and self‐monitoring (B = 0.553, SE = 0.253, β = 0.167, p = 0.030) SDLI constructs.ConclusionSDL among DH students can be cultivated by enhancing their learning motivation and self‐monitoring skills. This may be achieved by helping learners increase their internal locus of control and open‐mindedness. Future studies should explore exercises to help promote these traits.
The differential effects of palmitic acid and oleic acid on the metabolic response of hypothalamic astrocytes from male and female mice
Authors: Collado‐Perez Roberto , Chamoso‐Sánchez David , García Antonia , Fernández‐Alfonso María S. , Jiménez‐Hernáiz Maria , Canelles Sandra , Argente Jesús , Frago Laura M. , Chowen Julie A. 
Published: May 2024

AbstractDiets rich in saturated fats are more detrimental to health than those containing mono‐ or unsaturated fats. Fatty acids are an important source of energy, but they also relay information regarding nutritional status to hypothalamic metabolic circuits and when in excess can be detrimental to these circuits. Astrocytes are the main site of central fatty acid β‐oxidation, and hypothalamic astrocytes participate in energy homeostasis, in part by modulating hormonal and nutritional signals reaching metabolic neurons, as well as in the inflammatory response to high‐fat diets. Thus, we hypothesized that how hypothalamic astrocytes process‐specific fatty acids participates in determining the differential metabolic response and that this is sex dependent as males and females respond differently to high‐fat diets. Male and female primary hypothalamic astrocyte cultures were treated with oleic acid (OA) or palmitic acid (PA) for 24 h, and an untargeted metabolomics study was performed. A clear predictive model for PA exposure was obtained, while the metabolome after OA exposure was not different from controls. The observed modifications in metabolites, as well as the expression levels of key metabolic enzymes, indicate a reduction in the activity of the Krebs and glutamate/glutamine cycles in response to PA. In addition, there were specific differences between the response of astrocytes from male and female mice, as well as between hypothalamic and cerebral cortical astrocytes. Thus, the response of hypothalamic astrocytes to specific fatty acids could result in differential impacts on surrounding metabolic neurons and resulting in varied systemic metabolic outcomes.
Thinking outside of the (Western) Box: Cultural Psychology Perspectives on Creativity in Education
Authors: Dantas de Paula Luciana , Branco Angela , Glaveanu Vlad 
Published: May 2024

ABSTRACTThis paper expands upon the invitation to rethink how psychology has constructed knowledge, theories, and research while analyzing the epistemological foundations of educational practices in schools, especially those aimed at promoting creativity. Our goal is to critically explore the shortcomings of the traditional, Westernized individualistic, and mostly positivistic approach usually found in school contexts. To foster creativity, a more dialogical, socio‐cultural, and collaborative framework is suggested, involving multiple perspectives and possibility thinking to address current educational challenges. Through an examination of education and creativity, we analyze educational practices in Westernized societies and explore the possibilities that arise from non‐Western perspectives and dialogical approaches. The discussion is guided by the following questions: what kind of educational practices have been bolstered in Westernized societies? How do these relate to educating (with and for) creativity? A case study is included to provide concrete illustrations that substantiate our arguments. Incorporating decolonial frameworks into cultural and socio‐cultural perspectives, as well as in creativity research, would enrich the understanding of these fields. Decolonial approaches can offer valuable insights by addressing power relations inherent in knowledge construction and practice. Embracing these approaches enables these fields to contribute to a more nuanced and comprehensive understanding of human phenomena.
Survival rate of teeth adjacent and nonadjacent to dental implants: A retrospective cohort study
Authors: Chen Hsuan‐Hung , Lin Guo‐Hao , Kao Richard T. , Yeh Yu‐Ting 
Published: May 2024

AbstractBackgroundThe aim of this retrospective study was to investigate the risk of tooth loss for teeth adjacent and nonadjacent to dental implants.MethodsA total of 787 patients with an average follow‐up of 57.1 months were examined to define the tooth loss, cumulative survival rate, and odds ratio (OR) for teeth adjacent versus nonadjacent to implants. A multivariate logistic regression was employed to assess the association between dental history and various recorded etiologies of tooth loss among teeth adjacent to implants.ResultsThe incidence of tooth loss for teeth adjacent to implants was 8.1% at the tooth level and 15.1% at the patient level, while 0.7% and 9.5% at the tooth and patientlevel for teeth nonadjacent to implants. The 10‐year cumulative survival rate for teeth adjacent to implants was 89.2%, and the primary etiology of tooth loss was root fracture (45.2%). The risk of tooth loss among teeth adjacent versus nonadjacent to implants was significantly higher (OR 13.15). Among teeth adjacent to implants, root canal‐treated teeth had a significantly higher risk of tooth loss due to root fracture (OR 7.72), a history of existing restoration significantly increased the risk of tooth loss due to caries (OR 3.05), and a history of periodontitis significantly increased the risk of tooth loss due to periodontitis (OR 38.24).ConclusionThe present study demonstrated that after patients received dental implant treatment, teeth adjacent to implants showed a 13.2‐fold higher risk of tooth loss compared to teeth nonadjacent to implants, with the primary etiology being root fracture.
Effects of garlic‐derived fructan and oligofructose mixtures on intestinal health and constipation relief in mice
Authors: Xie Chanyuan , Gao Wei , Liang Xingdi , Chye Fook Yee 
Published: May 2024

AbstractBACKGROUNDGarlic polysaccharides (GPs) constitute over 75% of the dry weight of garlic. They are characterized by fructan with a 2,1‐β‐d‐Fruf backbone and 2,6‐β‐d‐Fruf branches. Studies have suggested a role for GPs in regulating gut microbiota but whether they possess a comprehensive function in maintaining intestinal well‐being and can serve as effective prebiotics remains unknown. To explore this, varied doses of GPs (1.25–5.0 g kg−1 body weight) and inulin (as a positive control) were administered to Kunming mice via gavage, and their effects on the intestinal epithelial, chemical, and biological barriers were assessed. A constipation model was also established using loperamide to investigate the potential effects of GPs on the relief of constipation.RESULTSAdministration of GPs significantly upregulated expression of tight‐junction proteins and mucins in Kunming mouse small‐intestine tissue. Garlic polysaccharides elevated cecal butyric acid content, reduced the abundance of Desulfobacterota, and decreased the ratio of Firmicutes to Bacteroidetes (the F/B ratio). Garlic polysaccharides also promoted the growth of Bacteroides acidifaciens and Clostridium saccharogumia. Tax4Fun functional predictions suggested the potential of GPs to prevent human diseases, reducing the risk of insulin resistance, infectious diseases, and drug resistance. Garlic polysaccharides also exhibited a beneficial effect in alleviating loperamide‐induced constipation symptoms by enhancing small intestinal transit, softening stool consistency, accelerating bowel movements, and promoting the release of excitatory neurotransmitters.CONCLUSIONSThese findings highlight the important role of GPs in maintaining gut fitness by enhancing intestinal barrier function and peristalsis. Garlic polysaccharides are promising prebiotics, potentially contributing to overall intestinal well‐being and health. © 2024 Society of Chemical Industry.
Direct laser patterning of glass mask for micro display using GHz bursts
Authors: Jung Woohyun , Kim Hyungsik , Mishchik Konstantin , Lee Kisang , Ryu Jekil , Lee Seung Joo , Jeong Seong Ho , Roh Cheol Lae 
Published: May 2024

AbstractDevelopment of high‐precision RGB patterning process is needed to implement high‐resolution micro display (OLEDoS) for next‐generation VR/AR products. In general, specially designed and manufactured masks are required to realize above 3000‐ppi high‐resolution display in structured OLED material deposition. In this study, we developed direct laser patterning IR‐fs optical system operating in MHz and GHz burst modes and evaluated its capability for precise micro‐drilling of aluminoborosilicate glass materials. The fine hole‐shaped pattern is produced at a minimum of 5 μm pitch level for about 0.6 in. area without sacrificing the glass strength. It is expected to contribute to the high precise manufacture of ultra fine mask (UFM) using thin glass platform corresponding to micro displays in the future.
Electrochemical Performance of Polyaniline‐Polyvanadate‐Copper Nanomaterials for the Detection of Benzoic Acid
Authors: Gao Yiming , Zhuang Lihong , Zhang Yanan , Zhang Yong , Pei Lizhai , Li Xinjiong 
Published: May 2024

AbstractThe introduction of nanomaterials as modified electrode materials into the field of electrochemical sensing is expected to improve the reliability, sensitivity, selectivity and repeatability of electrochemical sensors in detecting pollutants in the water environment. In this study, copper vanadate nanomaterials (Cu3V2O7(OH)2·2H2O, referred to as CVO) and Cu3V2O7(OH)2·2H2O/polyyaniline (PANI) composite nanomaterials (referred to as CVO/PANI) are successfully prepared and characterized by Fourier transform infrared spectrum (FTIR), X‐ray traveling‐action (XRD), scanning electron microscopy (SEM) and high‐resolution transmission electron microscopy (HR‐TEM). The modified glassy carbon electrodes (GCE) with these two materials are used for the detection of benzoic acid (BA) and exhibit excellent electrochemical sensing performance. The results show that two pairs of semi‐reversible redox peaks exist in both CVO and CVO/PANI modified glassy carbon electrode (GCE) in BA solution. The linear range of CVO and CVO/PANI nanomaterials‐modified GCE is 0.01–2 mm and 0.001–2 mm, and the limits of detection are 2.16 and 0.41 µm, respectively. PANI plays important role in the electrochemical responses of BA at CVO/PANI modified GCE. PANI enhances the intensities of CV peaks and electrochemical determination ability for BA.
BaTiO3 Catalyzed Ultrasonic‐Driven Piezoelectric‐Induced Reversible Addition‐Fragmentation Chain‐Transfer Polymerization in Aqueous Media
Authors: Zhang Yu , Zhang Junle , Xu Shuo , Shi Ge , He Yanjie , Qiao Xiaoguang , Pang Xinchang 
Published: May 2024

AbstractCompared with normal stimulus such as light and heat, ultrasonic possesses much deeper penetration into tissues and organs and has lower scattering in heterogeneous systems as a noninvasive stimulus. Reversible addition‐fragmentation chain‐transfer polymerization (RAFT) in aqueous media is performed in a commercial ultrasonic wash bath with 40 kHz frequency ultrasonic, in the presence of piezoelectric tetragonal BaTiO3 (BTO) nanoparticles. Owing to the electron transfer from BTO under the ultrasonic action, the water can be decomposed to produce hydroxyl radical (HO•) and initiate the RAFT polymerization (piezo‐RAFT). The piezo‐RAFT polymerization exhibits features of controllable and livingness, such as linear increase of molar mass and narrow molar mass distributions (Mw/Mn < 1.20). Excellent temporal control of the polymerization and the chain fidelity of polymers are illustrated by “ON and OFF” experiment and chain extension, separately. Moreover, this ultrasonic‐driven piezoelectric‐induced RAFT polymerization in aqueous media can be directly used for the preparation of piezoelectric hydrogel which have potential application for stress sensor.
Associations of essential metals with the risk of aortic arch calcification: a cross‐sectional study in a mid‐aged and older population of Shenzhen, China
Authors: Mo Mingxing , Yin Li , Wang Tian , Lv Ziquan , Guo Yadi , Shen Jiangang , Zhang Huanji , Liu Ning , Wang Qiuling , Huang Suli , Huang Hui 
Published: May 2024

AbstractVascular calcification is a strong predictor of cardiovascular events. Essential metals play critical roles in maintaining human health. However, the association of essential metal levels with risk of aortic arch calcification (AoAC) remains unclear. We measured the plasma concentrations of nine essential metals in a cross‐sectional population and evaluated their individual and combined effects on AoAC risk using multiple statistical methods. We also explored the mediating role of fasting glucose. In the logistic regression model, higher quartiles of magnesium and copper were associated with the decreased AoAC risk, while higher quartile of manganese was associated with higher AoAC risk. The least absolute shrinkage and selection operator penalized regression analysis identified magnesium, manganese, calcium, cobalt, and copper as key metals associated with AoAC risk. The weighted quantile sum regression suggested a combined effect of metal mixture. A linear and positive dose–response relationship was found between manganese and AoAC in males. Moreover, blood glucose might mediate a proportion of 9.38% of the association between manganese exposure and AoAC risk. In summary, five essential metal levels were associated with AoAC and showed combined effect. Fasting glucose might play a significant role in mediating manganese exposure‐associated AoAC risk.
A decentralized production approach to measure fuel performance of bus transportation systems
Authors: Kushwaha Shivam , Venkatesh Anand , Prawesh Shankar 
Published: May 2024

AbstractThis paper presents a comprehensive measure of fuel performance, considering economic and environmental factors using Data Envelopment Analysis (DEA). The study uses decentralized production approach, modeling two technology specifications, one with abatement and one without. The study focuses on the Indian public bus transport industry, treating carbon emissions as bad outputs with joint disposability alongside fossil fuels. Additionally, it examines fuel performance drivers through bootstrapped truncated regression. The findings reveal that maintenance practices and vehicle age negatively affect fuel performance, with the latter showing a non‐linear influence. As fuel prices rise, bus company managers increasingly adopt fuel‐saving practices.