bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Enantioselective Catalysis. Part 111. New Chiral Expanded Phosphanes Derived from Substituted Deltacyclenes.
Authors: BRUNNER H. , REIMER A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2,4‐Diphosphoranediyl‐1,3‐diphosphetanes.
Authors: SCHROEDEL H.‐P. , SCHMIDPETER A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Generation of Alkyl, Aminyl, and Alkoxy Radicals from Se‐Phenyl Benzoselenohydroximate Derivatives.
Authors: KIM S. , LEE T. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthesis of Thioesters and Selenoesters of Triflic Acid under Oxidative Conditions.
Authors: BILLARD T. , LANGLOIS B. R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Monoorganostannanes as Efficient Reagents for Palladium‐Catalyzed Coupling Reactions.
Authors: FOUQUET E. , PEREYRE M. , RODRIGUEZ A. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies Toward the Synthesis of Vinigrol. First Construction of the Tricyclic Ring System.
Authors: DEVAUX J.‐F. , HANNA I. , LALLEMAND J.‐Y. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Polyunsaturated Irregular Acyclic C25 Isoprenoid in a Methanogenic Archaeon.
Authors: SINNINGHE DAMSTE J. S. , SCHOUTEN S. , VAN VLIET N. H. , HUBER R. , GEENEVASEN J. A. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A hybrid finite element/finite difference algorithm for compressible/incompressible viscoelastic liquids
Authors: Guaily Amr , Epstein Marcelo 
Published: August 2010

AbstractA unified formulation is proposed for modelling compressible/incompressible viscoelastic liquids. The pure hyperbolic nature of the model overcomes some of the drawbacks of available models. The most important of these drawbacks is the mixed nature of the resulting systems of equations, with the subsequent consequence of having no general numerical algorithm for the solution. A new non‐dimensionalisation procedure is adopted. A hybrid least‐squares finite element/finite difference scheme coupled with a Newton‐Raphson's algorithm is used to solve the resulting system of equations. The method is used to predict the velocity and stress fields for different Weissenberg numbers for two benchmark problems.
Effect of L64 on the Phase Behavior of 1‐Dodecyl‐3‐methylimidazolium Chloride/Water System
Authors: Wang Luyan , Wu Zhiyan , Pei Meishan , Wu Xinzhou , Tao Xutang 
Published: August 2010

AbstractPhase behavior of ternary system involving surfactant‐like ionic liquid 1‐dodecyl‐3‐methylimidazolium chloride ([C12mim]Cl), water, and nonionic surfactant PEO‐PPO‐PEO block copolymer (Pluronic L64) is investigated at 25°C. Hexagonal (H1) and lamellar liquid crystal phase (Lα) are found in [C12mim]Cl/H2O/L64 system by using polarized optical microscopy (POM), small‐angle X‐ray scattering (SAXS) techniques and 2H NMR spectra. The phase structure (H1 phase), which is formed in [C12mim]Cl/H2O binary system, is not changed when L64 with a low concentration is added. However, phase transitions will occur from hexagonal to multiphases of H1 and cubic phases (C), then to Lα+C phases with constant [C12mim]Cl/H2O ratio and increasing L64 concentration. Moreover, at given L64 (5%, 20%) concentration, the lattice parameter of H1 or Lα phase decreases with increasing [C12mim]Cl/H2O ratio. Fourier transform infrared (FTIR) spectra indicate that the H‐bonded network comprising an imidazolium ring, chloride ion and water formed in [C12mim]Cl/H2O binary system is disrupted upon addition of L64. This is helpful to the phase transition, due to the decreasing of interfacial curvature induced by dehydration of hydrated layer after the addition of PEO block of L64.
Mechanistic Study of Ozone‐Water Reaction and Their Reaction Products with Gas Phase Elemental Mercury: A Computational Study
Authors: Vahedpour Morteza , Tozihi Manijeh , Nazari Fariba 
Published: August 2010

AbstractThe interaction of oxygen of water and central oxygen of ozone produces stable H2O‐O3 complex with no barrier. With decomposition of this complex through H‐abstraction by O3 and O‐abstraction by H2O, four possible product channels have been found. The reaction of mercury and the products of water‐ozone reaction have been studied. All geometrical and AIM parameters of intermediate, transition states, and the products of reactions are calculated and thermodynamic parameters are obtained. The negative value of free energy show that channels Hg+H2OO, Hg+H2O2 and Hg+H2O4 in hydrogen tetroxide form (HTO) may be the main reaction channels.
Chemical Stability and Electrical Property of BaCe0.7Zr0.2Nd0.1O3−α Ceramic
Authors: Wang Maoyuan , Qiu Ligan , Zhang Tong 
Published: August 2010

Abstract BaCe0.7Zr0.2Nd0.1O3−α ceramic was prepared by solid state reaction. Phase composition, surface and fracture morphologies of the material were characterized by using XRD and SEM, respectively. Chemical stability against carbon dioxide and water steam at the high temperature was tested. The conductivity and ionic transport number of the material were measured by ac impedance spectroscopy and gas concentration cell methods in the temperature range of 500–900°C in wet hydrogen and wet air, respectively. Using the ceramic as solid electrolyte and porous platinum as electrodes, the hydrogen‐air fuel cell was constructed, and the cell performance at the temperature from 500 to 900°C was examined. The results indicate that BaCe0.7Zr0.2Nd0.1O3−α was a single phase perovskite‐type orthorhombic system, with high density and good chemical stability in carbon dioxide and water steam atmospheres at the high temperature. The conductivity of the material in wet hydrogen and wet air was increased as the temperature rises. In wet hydrogen, the material was a pure protonic conductor with the protonic transport number of 1 from 500 to 600°C, a mixed conductor of proton and electron with the protonic transport number of 0.973–0.955 from 700 to 900°C. In wet air, the material was a mixed conductor of proton, oxide ion and electron hole. The protonic transport numbers were 0.002–0.003, and the oxide ionic transport numbers were 0.124–0.179. The fuel cell could work stably. At 900°C, the maximum short‐circuit current density and power output density were 156 mA·cm−2 and 40 mW·cm−2, respectively.
Recognizing Hybrid/Mixed G‐quadruplex in Human Telomeres by Using a Cyanine Dye Supramolecule with Confocal Laser Scanning Microscopy
Authors: Yang Qianfan , Xiang Junfeng , Yang Shu , Zhou Qiuju , Li Qian , Guan Aijiao , Zhang Xiufeng , Zhang Hong , Tang Yalin , Xu Guangzhi 
Published: August 2010

AbstractSingle‐stranded telomeric DNA tends to form a four‐base‐paired planar structure termed G‐quadruplex. Although kinds of G‐quadruplex structures in vitro have been documented in the presence of potassium or sodium, recognition of these DNA motifs (both in vitro and in vivo) is still an important issue in understanding the biological function of the G‐quadruplex structures in telomeres as well as developing anticancer agents. Herein we address this important question through the distinctive properties of a supramolecular system of cyanine dye 3,3′‐di(3‐sulfopropyl)‐4,5,4′,5′‐dibenzo‐9‐methyl‐thiacarbocyanine triethylammonium salt (MTC) upon binding to different DNA motifs. Interaction of MTC with hybrid/mixed G‐quadruplex results in a set of unique spectrophotometric signatures which are completely different from those arising from binding to other DNA motifs. Furthermore, such feature could be extended to map the locations of DNAs on interface. Linear duplex and mixed G‐quadruplex in human telomeres assembled on Au film and stained by MTC were directly recognized by confocal laser scanning microscopy (CLSM). All results suggested that MTC supramolecular system may be a good probe of specific G‐quadruplex structure.
Aptamer‐modified AuRe Nanoalloy Probe for Trace Hg2+ Using Resonance Scattering as Detection Technique
Authors: Jiang Zhiliang , Zhang Jing , Wen Guiqing , Liang Aihui , Liu Qingye , Kang Caiyan , He Xingcun 
Published: August 2010

AbstractThe AuRe nanoalloy particles in molar ratio of 9:1 were prepared by sodium borohydride procedure, and modified by single strand DNA (ssDNA) to prepare an aptamer AuRe nanoprobe (AuRessDNA) for Hg2+. In the pH 7.0 Na2HPO4‐NaH2PO4 buffer solution and in the presence of NaCl, Hg2+ interacted with AuRessDNA to form double‐stranded T‐Hg2+‐T mismatched and release AuRe nanoparticles that aggregate to large AuRe nanoparticles clusters causing the resonance scattering (RS) peak red shifting and the RS intensity enhanced linearly. On those grounds, 0.067–33.3 nmol·L−1 Hg2+ can be detected rapidly by the aptamer‐modified AuRe nanoparticles RS assay, with a detection limit of 0.04 nmol·L−1 Hg2+. If the aggregated AuRe particles were removed by membrane filtration, the excess AuRessDNA in the filtration solution exhibits catalytic effect on the new Te particle reaction between Na2TeO4 and SnCl2. As the concentration of Hg2+ increased, the AuRessDNA nanoparticles in the filtrate solution decreased, the RS intensity at 734 nm decreased linearly. The Hg2+ concentration (c) in the range of 0.00133–0.267 nmol·L−1 was linear to the decreased RS intensity (ΔI734nm), with a regression equation of ΔI= −786.4c−4.4, a correlation coefficient of 0.9975, and a detection limit of 0.9 pmol·L−1 Hg2+. This method was applied to the detection of Hg2+ in water samples, with satisfactory results.
Near‐Infrared Fluorimetric Determination of Copper(II) Ions Using CdHgTe Nanorods as Probe
Authors: Yu Mingchuan , Jin Yingqiong , Qi Xin , Bao Linjun , Qian Zhangsheng , Zhu Changqing 
Published: August 2010

AbstractStable water‐soluble CdHgTe nanorods with an emission wavelength at 722 nm, obtained by doping Hg2+ into CdTe nanorods, has been used as a near‐infrared region (NIR) probe to investigate their interaction with copper(II) ions. A new fluorimetric method for the determination of copper(II) ions has been developed based on the quenching effect of copper(II) ions on the emission of CdHgTe nanorods. The mechanism studies show that an effective electron transfer from nanorods to the copper(II) ions occurred based on the coordination reaction between copper(II) ions and the carboxyl groups on the nanorods surface, which could be responsible for the emission quenching of CdHgTe nanorods. Under optimum conditions, the linear range of the calibration curve for the determination of Cu2+ is from 8.0×10−9 to 1.0×10−6 mol/L and the detection limit is 2.0×10−9 mol/L. Owing to low background interference of NIR measurement, the proposed method displays relative high sensitivity and selectivity. Especially, some physiologically important cations almost do not interfere with the determination of Cu2+. The proposed method was also applied to the determination of trace Cu2+ in real aqueous samples with satisfactory results.
Pharmacophore Modeling and Virtual Screening of Novel Inhibitors for c‐Kit Kinase
Authors: Jiang Qinglin , Yang Qian , Liao Changjun , Zan Wang , Zang Zhihe 
Published: August 2010

AbstractThe stem cell factor receptor (c‐Kit) has been known to play critical roles in regulating numerous aspects of cellular behavior including cell growth, differentiation, migration and metabolism. In this investigation, a three‐dimensional pharmacophore model of c‐Kit inhibitors has been established by using the HypoGen algorithms implemented in the catalyst software package. The best quantitative pharmacophore model, hypothesis 1, which has the highest correlation coefficient (0.989), consists of one hydrogen bond acceptor, two hydrogen bond donors and one hydrophobic feature. To our knowledge, this is the first report on the pharmacophore modeling study of c‐Kit inhibitors. The best hypothesis, hypothesis 1, was used to screen molecular structural databases, including Specs and China Natural Products Database for potential lead compounds. The hit compounds were subsequently subjected to filtering by Lipinski's rules and docking study to refine the retrieved hits and as a result to reduce the rate of false positive. Finally 28 compounds were purchased or synthesized for further in vitro assay against several human tumour cell lines including A549, MCF‐7, HepG2 and PC‐3, in which c‐Kit is overexpressed. Two compounds show very low micromolar inhibition potency against the PC‐3 and HepG2 cell lines respectively. And they were selected for further modification and testing.
Synthesis of Novel Spiro Pyrrolidine and Pyrrolizine Derivatives by 1,3‐Dipolar Cycloaddition
Authors: Li Xiaofang , Zheng Aiting , Liu Bin , Yu Xianyong , Yi Pinggui 
Published: August 2010

AbstractThe 1,3‐dipolar cycloaddition of azomethine ylides derived from isatin and amino acids viz. sarcosine and proline to 2‐arylmethylidene‐5,6‐dihydroimidazo[2,1‐b]thiazol‐3(2H)‐ones afforded novel spiro pyrrolidines and pyrrolizidines regio‐ and stereoselectively in moderate yields. The products were characterized thoroughly by IR, MS, NMR together with elementary analysis.
One‐pot Preparation of Fluorinated Polyhydrobenzoacridine‐1‐one Derivatives under Microwave Irradiation and Solvent‐free Conditions
Authors: Jin Jianan , Zhang Jianmin , Liu Fengrui , Shang Wenli , Xin Yong , Zhu Shizheng 
Published: August 2010

AbstractA facile and efficient synthesis of fluorine‐containing polyhydrobenzoacridines was accomplished by a three‐component coupling of fluorinated aldehyde, α‐naphthylamine, and 1,3‐cyclohexanedione or dimedone under microwave irradiation and solvent‐free conditions without catalyst. All new compounds were obtained in moderate to good yields and characterized by standard spectroscopic methods.
Green and Highly Efficient Functionalization of Carbon Nanotubes by Combination of 1,3‐Dipolar Cycloaddition and Curtius Rearrangement Reactions
Authors: Peng Hongdan , Yang Zhe , Huang Shu , Liu Tianxi 
Published: August 2010

AbstractA facile and environmentally friendly strategy was developed for covalent modification of the convex surfaces of carbon nanotubes (CNT) through a combination of 1,3‐dipolar cycloaddition of azomethine ylides and Curtius rearrangement of carboxylic acid azides and its application in grafting polyamide 6 onto the surface of CNT was further investigated.
Convenient Synthesis of D‐Talose from D‐Galactose
Authors: Xiao Hualing , Wang Guangfa , Wang Peng , Li Yingxia 
Published: August 2010

AbstractThe rare and expensive D‐talose was conveniently synthesized from readily available D‐galactose in four steps with an overall yield of 58%. The key step was the inversion of equatorial 2‐OH of galactose to the axial one by SN2 reaction under the modified Lattrell‐Dax reaction conditions.
Addition of Acetone towards β‐Cyano‐α‐oxoesters Catalyzed by L‐Proline: Dynamic Kinetic Resolution
Authors: Wang Yajun , Zhang Yawen 
Published: August 2010

Abstractβ‐Cyano‐α‐oxoesters were found to undergo asymmetric aldol addition reaction with acetone in the presence of 10 mol% of L‐proline. With the racemic starting material, dynamic kinetic resolution (DKR) was achieved in quantitative yields with good diastreroselectivity of up to 85:15 dr and excellent ee up to 99% for the major diastereomer.
Synthesis, Photophysics and Morphology of a Conjugated Polymer with Azobenzene Building Block in the Backbone
Authors: Shen Dezhi , Pan Zhenxing , Xu Haibo , Cheng Si , Zhu Xiulin , Fan Lijuan 
Published: August 2010

AbstractA conjugate polymer poly[p‐(phenyleneethylene)‐alt‐(phenyleneazophenyleneethylene)] (PPEPAPE) containing azobenzene building block in the polymer backbone was synthesized via Sonogashira cross‐coupling of 4,4′‐diiodoazobenzene and 1,4‐diethynyl‐2,5‐didodecyloxybenzene. All the monomers and the resulting polymer were well characterized. The polymer had a relatively high molecular weight and showed very good solubility (≧10 mg/mL) in common organic solvents. The photophysics of this polymer in solution and in film was investigated. The surface morphology of the films was studied by scanning electron microscope (SEM) and the relationship between the morphology and absorbance was discussed. This polymer has good film‐forming property, broad absorbance and no emission, which might make it a good candidate for the photovoltaic material in the solar cell.
Synthesis of 3‐Benzoyl Acrylates/Acrylamides via Dehydrogenation of 3‐Benzoyl Propionates/Propionamides Using IBX/p‐TsOH
Authors: Li Ziyuan , Wang Yiyun , Tang Changhua , Xu Jinyi , Wu Xiaoming , Yao Hequan 
Published: August 2010

AbstractDehydrogenation by IBX/p‐TsOH is applied to the conversion of 3‐benzoyl propionates/propionamides to 3‐benzoyl acrylates/acrylamides in moderate to excellent yields. The reaction time for the dehydrogenation of 3‐benzoyl propionamides was remarkably shorter than that for the dehydrogenation of esters.
Design, Synthesis, and Biological Evaluation of Coumarin Derivatives Tethered to an Edrophonium‐like Fragment as Highly Potent and Selective Dual Binding Site Acetylcholinesterase Inhibitors
Authors: Pisani Leonardo , Catto Marco , Giangreco Ilenia , Leonetti Francesco , Nicolotti Orazio , Stefanachi Angela , Cellamare Saverio , Carotti Angelo 
Published: August 2010

AbstractA large series of substituted coumarins linked through an appropriate spacer to 3‐hydroxy‐N,N‐dimethylanilino or 3‐hydroxy‐N,N,N‐trialkylbenzaminium moieties were synthesized and evaluated as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors. The highest AChE inhibitory potency in the 3‐hydroxy‐N,N‐dimethylanilino series was observed with a 6,7‐dimethoxy‐3‐substituted coumarin derivative, which, along with an outstanding affinity (IC50=0.236 nM) exhibits excellent AChE/BChE selectivity (SI>300 000). Most of the synthesized 3‐hydroxy‐N,N,N‐trialkylbenzaminium salts display an AChE affinity in the sub‐nanomolar to picomolar range along with excellent AChE/BChE selectivities (SI values up to 138 333). The combined use of docking and molecular dynamics simulations permitted us to shed light on the observed structure–affinity and structure–selectivity relationships, to detect two possible alternative binding modes, and to assess the critical role of π–π stacking interactions in the AChE peripheral binding site.
Meat and components of meat and the risk of bladder cancer in the NIH‐AARP Diet and Health Study
Authors: Ferrucci Leah M. , Sinha Rashmi , Ward Mary H. , Graubard Barry I. , Hollenbeck Albert R. , Kilfoy Briseis A. , Schatzkin Arthur , Michaud Dominique S. , Cross Amanda J. 
Published: August 2010

AbstractBACKGROUND:Meat could be involved in bladder carcinogenesis via multiple potentially carcinogenic meat‐related compounds related to cooking and processing, including nitrate, nitrite, heterocyclic amines (HCAs), and polycyclic aromatic hydrocarbons (PAHs). The authors comprehensively investigated the association between meat and meat components and bladder cancer.METHODS:During 7 years of follow‐up, 854 transitional cell bladder‐cancer cases were identified among 300,933 men and women who had completed a validated food‐frequency questionnaire in the large prospective NIH‐AARP Diet and Health Study. The authors estimated intake of nitrate and nitrite from processed meat and HCAs and PAHs from cooked meat by using quantitative databases of measured values. Total dietary nitrate and nitrite were calculated based on literature values.RESULTS:The hazard ratios (HR) and 95% confidence intervals (CI) for red meat (HR for fifth quintile compared with first quintile, 1.22; 95% CI, 0.96‐1.54; Ptrend = .07) and the HCA 2‐amino‐1 methyl‐6‐phenylimidazo(4,5‐b)pyridine (PhIP) (HR, 1.19; 95% CI, 0.95‐1.48; Ptrend = .06) conferred a borderline statistically significant increased risk of bladder cancer. Positive associations were observed in the top quintile for total dietary nitrite (HR, 1.28; 95% CI, 1.02‐1.61; Ptrend = .06) and nitrate plus nitrite intake from processed meat (HR, 1.29; 95% CI, 1.00‐1.67; Ptrend = .11).CONCLUSIONS:These findings provided modest support for an increased risk of bladder cancer with total dietary nitrite and nitrate plus nitrite from processed meat. Results also suggested a positive association between red meat and PhIP and bladder carcinogenesis. Cancer 2010. © 2010 American Cancer Society.
Skin melanoma of the head and neck: Prognostic factors and recurrence‐free survival in 512 patients
Authors: Andersson Anders P. , Gottlieb Jorgen , Drzewiecki Krzysztof T. , Hou‐Jensen Klaus , Sondergaard Knud 
Published: August 2010

AbstractThe clinicopathologic and therapeutic data of 512 patients, with clinical Stage I invasive head and neck melanoma of the skin were retrospectively evaluated. There were 287 females and 225 males. Median age at primary‐surgery was 65 years (range, 18 to 96 years). Median observation period was 5 years (range, 1 month to 25 years). Site of first recurrence was local in 7% (38 of 512), regional in 13% (67 of 512) and distant in 6% (31 of 512). Sex, age, ulcerated tumor, and tumor thickness were found to act as independent risk factors to recurrence‐free survival by Cox multivariate regression analysis. In addition, size of excision margin was found to be of no significance to survival without relapse when adjusting for the independent risk factors.