bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Monstrous Conclusion
Authors: Stroppa Luca 
Published: May 2024

AbstractThis paper introduces the Monstrous Conclusion, according to which, for any population, there is a better population consisting of just one individual (the Monster). The Monstrous Conclusion is deeply counterintuitive. I defend a version of Prioritarianism as a particularly promising population axiology that does not imply the Monstrous Conclusion. According to this version of Prioritarianism, which I call Asymptotic Prioritarianism, there is diminishing marginal moral importance of individual welfare that can get close to, but never quite reach, some upper limit. I argue that Asymptotic Prioritarianism faces a theoretical cost, that I call the Absolute Priority Principle. However, the Absolute Priority Principle is an extreme version of what I call the Trade-off Condition, an already noteworthy problem facing other (more widely endorsed) versions of Prioritarianism. I conclude that it is better for a theory to imply the Absolute Priority Principle and avoid the Monstrous Conclusion than to imply the Monstrous Conclusion and the Trade-off Condition. The potential for Asymptotic Prioritarianism is substantial.
Novel approaches to improve rooting of microshoots, acclimatization and plant growth of Pyrodwarf pear rootstock
Authors: Nawandish Farangis , Dumanoğlu Hatice , Sarıkamış Gölge 
Published: May 2024

AbstractEx vitro root formation of micro cuttings of Pyrodwarf pear rootstock (Pyrus communis L.) using floating perlite bed and the effects of Indole-3-butric acid (IBA) treatments on the growth performance after five months were determined. Micro cuttings were dipped in 25, 50, 100 or 150 mg L–1 IBA solutions for 10 s for ex vitro rooting, except for the control. The floating perlite bed cultures were kept for 4 weeks at 25 ± 2ºC with a photoperiod of 16 h light (35 μmol∙m−2∙s−1). At the end of the rooting experiment, there were no statistically significant differences among treatments in terms of rooting percentages (77.8%-81.1%), number of roots (1.9–2.5) and the length of the longest root (22.8–36.8 mm). In the plant growth experiment, ex vitro rooted micro cuttings treated with 25 and 50 mg L–1 IBA and the control were maintained under greenhouse conditions for 5 months to determine the growth performance of the plants. Growth performance was higher in terms of stem diameter, root and stem dry weights of plants rooted with 50 mg L–1 IBA determined as 4.5 mm, 196.5 mg and 704.7 mg, respectively. In conclusion, it was found that the floating perlite bed method was effective in ex vitro rooting and acclimatization. Ex vitro rooting with 50 mg L−1 IBA improved plant growth performance in greenhouse.
Effects of temperature and moisture fluctuations for suitable use of raw-crushed wind-turbine blade in concrete
Authors: Revilla-Cuesta Víctor , Hurtado-Alonso Nerea , Manso-Morato Javier , Serrano-López Roberto , Manso Juan M. 
Published: May 2024

AbstractRaw-crushed wind-turbine blade (RCWTB), a waste from the recycling of wind-turbine blades, is used as a raw material in concrete in this research. It contains not only fiberglass-composite fibers that bridge the cementitious matrix but also polyurethane and balsa-wood particles. Therefore, concrete containing RCWTB can be notably affected by moisture and temperature fluctuations and by exposure to high temperatures. In this research, the performance of five concrete mixes with 0.0%, 1.5%, 3.0%, 4.5%, and 6.0% RCWTB, respectively, is studied under moist/dry, alternating-sign-temperature-shock, and high-temperature-shock tests. Two damage mechanisms of RCWTB within concrete were found through these tests: on the one hand, micro-cracking of the cementitious matrix, which was verified by microscopic analyses and was dependent on concrete porosity; on the other, damage and degradation of the RCWTB components, as the polyurethane melted, and the balsa-wood particles burned. Both phenomena led to larger remaining-strain levels and reduced concrete compressive strength by up to 25% under temperature and humidity variations, although the bridging effect of the fiberglass-composite fibers was effective when adding RCWTB amounts higher than 3.0%. The compressive-strength loss after the high-temperature-shock test increased with the RCWTB content, reaching maximum values of 8% after an exposure time of 7 days. Statistical analyses revealed that effect of the RCA amount in the concrete was conditioned by the exposure times in all the tests. The accurate definition of those times is therefore key to set an RCWTB content in concrete that ensures its suitable behavior under the environmental conditions analyzed.
Life cycle assessment as a driver for process optimisation of cellobiose lipids fermentation and purification
Authors: Oraby Amira , Briem Ann-Kathrin , Bippus Lars , Rupp Steffen , Zibek Susanne 
Published: May 2024

Abstract
Purpose
Cellobiose lipids (CL) are biosurfactants produced by various Ustilaginaceae species in aerobic fermentations. They show high potential for application as alternatives to conventional oleochemical- or petrochemical surfactants. To ensure their environmentally friendly performance, we aimed to assess CL production from a life cycle perspective at an early developmental stage to identify process steps that have the highest impact on the environment. With this information, optimisation approaches can be derived.

Materials and methods
Following a cradle-to-gate approach, we modelled the CL fermentation and purification process based on experimental data from the lab scale and process simulation data at a 10 m3 scale. For LCA, the impact categories (IC) abiotic depletion potential (ADP), eutrophication potential, photochemical ozone creation potential, global warming potential, acidification potential, and the primary energy demand were calculated for all process steps. Based on the obtained results, process bottlenecks were identified, and alternative process scenarios varying the related process parameters were simulated. These were used to assess the environmental impact reduction potential (EIRP) of an optimised process and draw recommendations for experimental process optimisation.

Results and discussion
The obtained results showed that the fermentation caused ~ 73% of ADP and more than 85% of all other ICs. The major contributor was the electricity consumption for continuous fermenter aeration. Thus, reducing the fermentation duration from the initial 14 to 5 days would result in a decrease in all investigated ICs of up to ~ 27–52%. An increase in CL concentration results in a decrease in all ICs of a similar magnitude due to the higher yield per batch at comparable energy and material consumption. Although the share of purification process steps to all ICs is overall relatively small, implementing foam fractionation for in situ product recovery showed an additional EIRP of 18–27% in all purification IC shares.

Conclusions
The conducted LCA showed that overall, more EIRP can be achieved by optimising fermentation process parameters compared to purification process steps. This is mainly due to the long fermentation duration and large energy consumption for fermenter aeration. This highlights the importance of using LCA as a driver for process optimisation to identify process steps with high EIRP. While some of the results are specific to CL, other obtained results can be transferred to other fermentations.
Conducting sustainability research in the anthropocene: toward a relational approach
Authors: Böhme Jessica , Spreitzer Eva-Maria , Wamsler Christine 
Published: May 2024

AbstractScholars and practitioners are urgently highlighting the need to apply a relational approach to effectively address societal crises. At the same time, little is known about the associated challenges, and there is little advice regarding how to operationalize this approach in sustainability science. Against this background, this article explores how we can break out of our current paradigms and approaches, and instead apply relational thinking, being, and acting in the way we conduct research. To achieve this, we systematically list all major research phases, and assess possible pathways for integrating a relational paradigm for each step. We show that moving toward a relational paradigm requires us to methodically question and redefine existing theories of change, concepts, and approaches, for instance by combining abductive reasoning, first-person inquiries, and decentering the human through critical complexity theory. Challenging mainstream thought, and daring to ask different questions in each step is crucial to ultimately shift scientific norms and systems. Hence, we offer a catalog of questions that may help to systematically integrate relational being, thinking, and acting into the process, as a tool for transforming current paradigms in research, and associated education and practice. Finally, we highlight the importance of further research to develop and refine our outcomes.
The mediating role of positive body image
between friendship qualities, well-being strategies and identity development among
adolescents
Authors: Eryılmaz Ali , Kara Ahmet , Uzun Abdullah Ensar 
Published: May 2024

AbstractThis study aimed to explore the mediating role of body image in the
association between The utilization of strategies aimed at enhancing subjective
well-being, friendship qualities, and identity development. The participants
consisted of 270 early adolescents, comprising 157 girls (58.15%) and 113
boys (41.85%). Data were collected using several scales, including the
“Body Appreciation Scale,” “Subjective Well-Being Increasing
Strategies Scale for Adolescents,” “Friendship Qualities
Scale,” and “The Dimensions of Identity Development Scale.”
Two-stage structural equation modeling was employed to analyze the gathered data.
The findings indicated a positive model of identity development in adolescents,
highlighting that subjective well-being increasing strategies contribute positively
to identity development, and this relationship is mediated by positive body image.
Furthermore, the study found that positive body image also mediates the association
between adolescents’ identity development and the establishment of quality
friendships.
Filling data gaps in long-term solar UV monitoring by statistical imputation methods
Authors: Heinzl Felix , Lorenz Sebastian , Scholz-Kreisel Peter , Weiskopf Daniela 
Published: May 2024

AbstractKnowledge of long-term time trends of solar ultraviolet (UV) radiation on ground level is of high scientific interest. For this purpose, precise measurements over a long time are necessary. One of the challenges solar UV monitoring faces is the permanent and gap-free data collection over several decades. Data gaps hamper the formation and comparison of monthly or annual means, and, in the worst case, lead to incorrect conclusions in further data evaluation and trend analysis of UV data. For estimating data to fill gaps in long-term UV data series (daily radiant exposure and highest daily irradiance), we developed three statistical imputation methods: a model-based imputation, considering actual local solar radiation conditions using predictors correlated to the local UV values in an empirical model; an average-based imputation based on a statistical approach of averaging available local UV measurement data without predictors; and a mixture of these two imputation methods. A detailed validation demonstrates the superiority of the model-based imputation method. The combined method can be considered the best one in practice. Furthermore, it has been shown that the model-based imputation method can be used as an useful tool to identify systematic errors at and between calibration steps in long-term erythemal UV data series.
X-ray screening of donated wild game is insufficient to protect children from lead exposure
Authors: Buenz Eric J. , Parry Gareth J. , Hunter Simon , Powell Garret M. , Berghamer Dominik , Cieraad Ellen , Hampton Jordan O. , Arnemo Jon M. , Bauer Brent A. 
Published: May 2024

AbstractWorldwide hunters distribute game meat as a gesture of community bonding and as an essential nutritional resource for those facing food insecurity, especially among children and adolescents. Nonetheless, the risk of lead (Pb) contamination from lead-based bullets is not widely acknowledged. Although medical radiography (X-ray) is the standard method to detect lead in meat donations, its efficacy in conclusively identifying lead contamination in game meat samples remains unknown. To address this deficiency, hunters-provided game meat samples were analyzed using both X-ray and inductively-coupled plasma mass spectrometry (ICP-MS). By ICP-MS, 48% of these samples contained lead levels exceeding the daily intake benchmarks for children, including the samples in which no lead was identified by X-ray screening. This finding means that food insecure individuals need to make an unenviable decision between risking lead exposure in donated meat or forgoing a potentially critical food source.
Sociocultural Factors Influence on Burden and Stress of Caregivers of Children with Epilepsy
Authors: Schiller Katharina , Dassi Christelle , Berrahmoune Saoussen , Frauscher Birgit , Myers Kenneth A. 
Published: May 2024

ABSTRACT:We evaluated stress and burden in epilepsy patient caregivers in a pediatric neurology clinic. Caregivers of 102 children with epilepsy completed the Caregivers’ Assessment of Difficulty Index and a questionnaire regarding caregiver sociocultural characteristics. A multiple linear regression statistical analysis found that caregiver burden was significantly increased for those who had a second child with a chronic disease, sole caregivers and for those with children with drug-resistant epilepsy. Caregiver stress was significantly increased for caregivers with a native language other than English or French, caregivers who had a second child with a chronic disease and sole caregivers.
Evaluating NMT using the non-inferiority principle
Authors: do Campo Bayón María , Sánchez-Gijón Pilar 
Published: May 2024

Abstract
The aim of this article is to propose a new neural machine translation (NMT) evaluation method based on the non-inferiority principle. In order to do that, we evaluate raw machine translation (MT) in terms of naturalness, which for this research is defined as not just the lack of fluency errors but also meeting the linguistic expectations of Galician end users when reading original texts in Galician. Our main objective is, in the first place, to validate the new methodology presented in our previous study by evaluating an NMT engine from Spanish into Galician for the social media domain that was retrained with a new Twitter corpus. This new methodology and NMT engine were applied after analyzing the conclusions of a pilot survey conducted among Twitter users to evaluate their perception of tweets translated from Spanish into Galician with our NMT engine created with a corpus of tweets. As in our preliminary study, our aim is to propose a robust quality approximation method based on the reception parameters of end users’ perceptions. This new survey was conducted in December of 2022 with the participation of 228 Galician-speaking Twitter users. Among the main changes proposed are the inclusion of more information about the participant profile, so the non-inferiority principle can be also evaluated according to these parameters; the inclusion of a new typology of tweets, the threads; the provision of context by means of presenting the tweets in their original display as shown in the Twitter app; a change in the number of tweets evaluated and the number of different questionnaires; the change in the distribution of the questionnaires; and the inclusion of an error classification human evaluation conducted by professional linguists to correlate the findings. We will present the steps carried out following the conclusions of the pilot study, describe the new study’s design, analyze the new findings, and present the final conclusions regarding the engine and the evaluation method based on the non-inferiority principle. Finally, we will also provide some examples of the use of this new methodology in the translation industry.
The prophylactic and therapeutic impact of Trichinella spiralis larvae excretory secretory antigens- loaded Ca-BTC metal organic frameworks on induced murine colitis
Authors: Fawzy E.M. , Selim M.A. , Mostafa N. E. , Abdelhameed R.M. , Darwish A.M. , Yousef A.M. , Alabiad M.A. , Ibrahim M.N. , Fawzy H.M. , Abdel Hamed E.F. 
Published: May 2024

Abstract
Background: Inflammatory bowel disease is an autoimmune disease that affects the gut. T. spiralis larvae (E/S Ags) loaded on calcium-benzene-1,3,5-tricarboxylate metal-organic frameworks (Ca-BTC MOFs) were tested to determine whether they might prevent or cure acetic acid-induced murine colitis. Methods: T. spiralis larvae E/S Ags/Ca-BTC MOFs were used in prophylactic and therapeutic groups to either precede or follow the development of murine colitis. On the seventh day after colitis, mice were slaughtered. The effect of our target antigens on the progress of the colitis was evaluated using a variety of measures, including survival rate, disease activity index, colon weight/bodyweight, colon weight/length) ratios, and ratings for macroscopic and microscopic colon damage. The levels of inflammatory cytokines (interferon-γ and interleukin-4), oxidative stress marker malondialdehyde, and glutathione peroxidase in serum samples were evaluated. Foxp3 T-reg expression was carried out in colonic and splenic tissues. Results: T. spiralis larvae E/S Ags/Ca-BTC MOFs were the most effective in alleviating severe inflammation in murine colitis. The survival rate, disease activity index score, colon weight/length and colon weight/bodyweight ratios, and gross and microscopic colon damage scores have all considerably improved. A large decrease in proinflammatory cytokine (interferon-γ) and oxidative stress marker (malondialdehyde) expression and a significant increase in interleukin-4 and glutathione peroxidase expression were obtained. The expression of Foxp3+ Treg cells was elevated in colonic and splenic tissues. Conclusion: T. spiralis larvae E/S Ags/Ca-BTC MOFs had the highest anti-inflammatory, antioxidant, and cytoprotective capabilities against murine colitis and might be used to develop new preventative and treatment strategies.
Ectoparasite and bacterial population genetics and community structure indicate extent of bat movement across an island chain
Authors: McKee Clifton D. , Peel Alison J. , Hayman David T. S. , Suu-Ire Richard , Ntiamoa-Baidu Yaa , Cunningham Andrew A. , Wood James L. N. , Webb Colleen T. , Kosoy Michael Y. 
Published: May 2024

AbstractFew studies have examined the genetic population structure of vector-borne microparasites in wildlife, making it unclear how much these systems can reveal about the movement of their associated hosts. This study examined the complex host–vector–microbe interactions in a system of bats, wingless ectoparasitic bat flies (Nycteribiidae), vector-borne microparasitic bacteria (Bartonella) and bacterial endosymbionts of flies (Enterobacterales) across an island chain in the Gulf of Guinea, West Africa. Limited population structure was found in bat flies and Enterobacterales symbionts compared to that of their hosts. Significant isolation by distance was observed in the dissimilarity of Bartonella communities detected in flies from sampled populations of Eidolon helvum bats. These patterns indicate that, while genetic dispersal of bats between islands is limited, some non-reproductive movements may lead to the dispersal of ectoparasites and associated microbes. This study deepens our knowledge of the phylogeography of African fruit bats, their ectoparasites and associated bacteria. The results presented could inform models of pathogen transmission in these bat populations and increase our theoretical understanding of community ecology in host–microbe systems.
The effect of antipsychotic medications on QTc and delirium in paediatric cardiac patients with ICU delirium
Authors: John Carol J. , Engler Meghan , Zaki Hania , Crooker Anna , Cabrera Maria , Golden Cassidy , Whitehill Robert , Xiang Yijin , Liu Katie , Fundora Michael P. 
Published: May 2024

AbstractObjective:Children with prolonged hospital admissions for CHD often develop delirium. Antipsychotic medications (APMs) have been used to treat delirium but are known to prolong the QTc duration. There is concern for prolongation of the QTc interval in cardiac patients who may be more vulnerable to electrocardiogram (ECG) changes and may have postoperative QTc prolongation already. The goal of this study was to determine the effect of APM on QTc duration in postoperative paediatric cardiac patients and determine the effect of quetiapine and risperidone in treating delirium and QTc prolongation.Design:Retrospective study, July 1, 2017–May 31, 2022.Setting:Tertiary children’s hospital.Patients:Included were patients admitted to the paediatric cardiac ICU at Children’s Healthcare of Atlanta.Interventions:None.Measurements and Main Results:ECGs, delirium scores, and drug information were collected. Delirium was defined as Cornell Assessment of Pediatric Delirium (CAPD) score >9. Mixed effect models were performed to evaluate the effect of surgery on QTc change and the effect of antipsychotics on QTc and CAPD changes. There were 139 children, 55% male and 67% surgical admissions. Median age was 5.9 months. Mean QTc increased after cardiac surgery by 18 ms (p = 0.014, 95% CI 3.65–32.4). There was no significant change in QTc after antipsychotic administration (p = 0.064). The mean CAPD score decreased (12.5–7.2; p < 0.001). Quetiapine had the most improvement in delirium, and risperidone had the least improvement (77.8%, n = 14; 37.8%, n = 34, respectively; p = 0.002).Conclusions:The QTc interval did not have a statistically significant change after the administration of antipsychotics, while there was improvement in the CAPD score. APMs may be administered safely without significant prolongation of the QTc and are an effective treatment for delirium.
Cycles and their important shocks: completing the investigation
Authors: Gillman Max , Pagan Adrian 
Published: May 2024

Abstract
The paper looks at the question of measuring the importance of shocks to cycles. We consider two types of cycles - oscillations and those summarized by the NBER that require a study of growth in activity to establish turning points in the level of activity. The latter demarcate expansions and contractions. We establish a connection between these two concepts of cycles that shows shocks may have very different effects on each. As an application we look at a question that has often been asked over how important technology shocks are to cycles in activity? Some recent research concludes that total factor productivity (TFP) shocks are not important for oscillations and therefore models should be designed to reflect that. Using the same data we show that TFP shocks are very important to both types of cycles.