bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction
Authors: Rodella Luigi Fabrizio , Favero Gaia , Boninsegna Ramon , Buffoli Barbara , Labanca Mauro , Scarì Giorgio , Sacco Luigi , Batani Tiziano , Rezzani Rita 
Published: July 2011

AbstractAn interesting clinical option for optimizing healing tissue is the use of platelet concentrate. Platelets contain high quantities of growth factors, among these TGF‐β1 and VEGF, which are known to be implicated in tissue regeneration. CGF is produced by processing blood samples with a special centrifuge device; three layers are formed: top acellular plasma (PPP), middle CGF and bottom red blood cells (RBC) layers. Given that to date there are no data concerning the biological characteristic of CGF, the aim of this study was to evaluate the presence of TGF‐β1 and VEGF in CGF and also in PPP and RBC layers. In addition, since circulating stem cells are recruited from blood to injured tissue for healing we also evaluated the presence of CD34 positive cells. Our data show the presence of TGF‐β1 and VEGF in CGF and RBC layers. In addition, we show CD34 positive cells in CGF. Microsc. Res. Tech., 2011. © 2010 Wiley‐Liss, Inc.
Synergistic anticancer activity of curcumin and catechin: An in vitro study using human cancer cell lines
Authors: Manikandan R. , Beulaja M. , Arulvasu C. , Sellamuthu S. , Dinesh D. , Prabhu D. , Babu G. , Vaseeharan B. , Prabhu N.M. 
Published: July 2011

AbstractThe most practical approach to reduce morbidity and mortality of cancer is to delay the process of carcinogenesis by usage of anticancer agents. This necessitates that safer compounds are to be critically examined for anticancer activity especially, those derived from natural sources. A spice commonly found in India and the surrounding regions, is turmeric, derived from the rhizome of Curcuma longa and the major active component is a phytochemical termed curcumin. Green tea is one of the most popular beverages used worldwide, produced from the leaves of evergreen plant Camellia sinensis and the major active ingredients are polyphenolic compounds known as catechins. In this study, synergistic anticancer activity of curcumin and catechin was evaluated in human colon adenocarcinoma HCT 15, HCT 116, and human larynx carcinoma Hep G‐2 cell lines. Although, both curcumin or catechin inhibited the growth of above cell lines, interestingly, in combination of both these compounds highest level of growth control was observed. The anticancer activity shown is due to cytotoxicity, nuclear fragmentation as well as condensation, and DNA fragmentation associated with the appearance of apoptosis. These results suggest that curcumin and catechin in combination can inhibit the proliferation of HCT 15, HCT 116, as well as Hep G‐2 cells efficiently through induction of apoptosis. Microsc. Res. Tech., 2011. © 2011 Wiley Periodicals, Inc.
Hamilton cycle and Hamilton path extendability of Cayley graphs on abelian groups
Authors: MiklaviČ Štefko , Šparl Primož 
Published: July 2011

AbstractIn this paper the concepts of Hamilton cycle (HC) and Hamilton path (HP) extendability are introduced. A connected graph Γ isn‐HC‐extendableif it contains a path of lengthnand if every such path is contained in some Hamilton cycle of Γ. Similarly, Γ isweakly n‐HP‐extendableif it contains a path of lengthnand if every such path is contained in some Hamilton path of Γ. Moreover, Γ isstrongly n‐HP‐extendableif it contains a path of lengthnand if for every such pathPthere is a Hamilton path of Γ starting withP. These concepts are then studied for the class of connected Cayley graphs on abelian groups. It is proved that every connected Cayley graph on an abelian group of order at least three is 2‐HC‐extendable and a complete classification of 3‐HC‐extendable connected Cayley graphs of abelian groups is obtained. Moreover, it is proved that every connected Cayley graph on an abelian group of order at least five is weakly 4‐HP‐extendable. Copyright © 2011 Wiley Periodicals, Inc. J Graph Theory
Adaptive response of single and binary Pseudomonas aeruginosa and Escherichia coli biofilms to benzalkonium chloride
Authors: Machado Idalina , Lopes Susana Patrícia , Sousa Ana Margarida , Pereira Maria Olívia 
Published: July 2011

AbstractThe main goal of this work was to examine whether the continuous exposure of single and binary P. aeruginosa and E. coli biofilms to sub‐lethal benzalkonium chloride (BC) doses can induce adaptive response of bacteria. Biofilms were formed during 24 h and then put continuously in contact with BC for more 5 days. The six‐day‐old adapted biofilms were then submitted to BC challenge, characterized and inspected by SEM. Both single and binary adapted biofilms have clearly more biomass, polysaccharides and proteins and less activity even though the number of cells was identical. After BC treatment, adapted biofilms maintained their mass and activity. SEM examination revealed that those adapted biofilms had a slimier and denser matrix that became thicker after BC treatment. Continuous exposure of bacteria to antimicrobials can lead to development of biofilms encompassing more virulent and tolerant bacteria. This adaptive resistance can be the result of a phenotypic adaptation, a genetic acquired resistance or both. Instead of eradicating biofilms and kill microorganisms, the use of a disinfectant can, favour biofilm formation and tolerance. This must be a genuine concern as it can happen in clinical environments, where the use of antimicrobials is unavoidable. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Determination of optimum harvest maturity and physico‐chemical quality of Rastali banana (Musa AAB Rastali) during fruit ripening
Authors: Kheng Tee Yei , Ding Phebe , Abdul Rahman Nor Aini 
Published: July 2011

AbstractBACKGROUND: A series of physico‐chemical quality (peel and pulp colours, pulp firmness, fruit pH, sugars and acids content, respiration rate and ethylene production) were conducted to study the optimum harvest periods (either week 11 or week 12 after emergence of the first hand) of Rastali banana (Musa AAB Rastali) based on the fruit quality during ripening.RESULT: Rastali banana fruit exhibited a climacteric rise with the peaks of both CO2 and ethylene production occurring simultaneously at day 3 after ripening was initiated and declined at day 5 when fruits entered the senescence stage. De‐greening was observed in both of the harvesting weeks with peel turned from green to yellow, tissue softening, and fruits became more acidic and sweeter as ripening progressed. Sucrose, fructose and glucose were the main sugars found while malic, citric and succinic acids were the main organic acids found in the fruit.CONCLUSION: Rastali banana harvested at weeks 11 and 12 can be considered as commercial harvest period when the fruits have developed good organoleptic and quality attributes during ripening. However, Rastali banana fruit at more mature stage of harvest maturity taste slightly sweeter and softer with higher ethylene production which also means the fruits may undergo senescence faster than fruit harvested at week 11. Copyright © 2011 Society of Chemical Industry
Induction of mud crab (Scylla paramamosain) tropomyosin and arginine kinase specific hypersensitivity in BALB/c mice
Authors: Liu Guang‐Ming , Li Bing , Yu Hui‐Lin , Cao Min‐Jie , Cai Qiu‐Feng , Lin Jiang‐Wei , Su Wen‐Jin 
Published: July 2011

AbstractBACKGROUND: Shellfish hypersensitivity is among the most common food allergies. The allergens tropomyosin (TM) and arginine kinase (AK) from mud crab (Scylla paramamosain) were purified to homogeneity. BALB/c female mice were sensitized with TM and AK by intragastric administration. Mice treated with normal saline served as the negative control (NC) group.RESULTS: Compared with NC group, mice that were treated with TM and AK developed reduced activity; meanwhile, their scratching behavior and specific‐IgE level were increased. Specific‐CD4 + T cells were significantly elevated in the splenocyte cultures of the mice upon TM and AK stimulation. However, compared with the positive control group (ovalbumin, OVA), there was no significant difference. The expression of IL‐4 in culture cells stimulated by TM, AK, and OVA group showed significant differences from the NC group, respectively.CONCLUSION: These results indicated that a BALB/c mouse model for sensitization to TM and AK from mud crab was successfully established, and the Th2 response was observed, displaying increased immunoglobulin E levels, together with the production of interleukin 4 and allergic symptoms. Copyright © 2011 Society of Chemical Industry
Enhancing aspalathin stability in rooibos (Aspalathus linearis) ready‐to‐drink iced teas during storage: the role of nano‐emulsification and beverage ingredients, citric and ascorbic acids
Authors: de Beer Dalene , Joubert Elizabeth , Viljoen Melvi , Manley Marena 
Published: July 2011

AbstractBACKGROUND: The effects of citric and ascorbic acids on the stability of aspalathin in rooibos (Aspalathus linearis) ready‐to‐drink (RTD) formulations containing fermented rooibos extract (FR), aspalathin‐enriched green rooibos extract (GR) and aspalathin‐enriched green rooibos extract ascorbic acid solubilisate (GR‐solubilisate) were investigated during storage (12 weeks at 25 °C).RESULTS: Storage of iced tea formulations containing FR and GR extracts reduced their flavonoid content. The aspalathin content of FR iced tea without citric or ascorbic acid was reduced to undetectable levels by week 8 of storage. Addition of citric acid resulted in improved stability of aspalathin, but ascorbic acid did not impart additional stability. Iso‐orientin and orientin were less affected than aspalathin, presumably owing to partial conversion of aspalathin to these flavones. Similar results were obtained for GR iced tea formulations. Improved stability of aspalathin was noted in iced tea containing GR‐solubilisate with or without citric acid. Lower pH was shown to favour stability, especially for fermented rooibos iced teas.CONCLUSION: Citric and ascorbic acids contribute to the stability of rooibos flavonoids during storage. Differences in stability between formulations are not due to pH differences but may be related to the matrix. Copyright © 2011 Society of Chemical Industry
A new high‐throughput method utilizing porous silica‐based nano‐composites for the determination of partition coefficients of drug candidates
Authors: Yu Chih H. , Tam Kin , Tsang Shik C. 
Published: July 2011

AbstractWe show that highly porous silica‐based nanoparticles prepared via micro‐emulsion and sol–gel techniques are stable colloids in aqueous solution. By incorporating a magnetic core into the porous silica nano‐composite, it is found that the material can be rapidly separated (precipitated) upon exposure to an external magnetic field. Alternatively, the porous silica nanoparticles without magnetic cores can be equally separated from solution by applying a high‐speed centrifugation. Using these silica‐based nanostructures a new high‐throughput method for the determination of partition coefficient for water/n‐octanol is hereby described. First, a tiny quantity of n‐octanol phase is pre‐absorbed in the porous silica nano‐composite colloids, which allows an establishment of interface at nano‐scale between the adsorbed n‐octanol with the bulk aqueous phase. Organic compounds added to the mixture can therefore undergo a rapid partition between the two phases. The concentration of drug compound in the supernatant in a small vial can be determined by UV–visible absorption spectroscopy. With the adaptation of a robotic liquid handler, a high‐throughput technology for the determination of partition coefficients of drug candidates can be employed for drug screening in the industry based on these nano‐separation skills. The experimental results clearly suggest that this new method can provide partition coefficient values of potential drug candidates comparable to the conventional shake‐flask method but requires much shorter analytical time and lesser quantity of chemicals.
Case report on the use of cognitive processing therapy–cognitive, enhanced to address heavy alcohol use
Authors: McCarthy Elissa , Petrakis Ismene 
Published: July 2011

AbstractThere is a high rate of co‐occurring alcohol dependence (AD) in individuals with posttraumatic stress disorder (PTSD). Cognitive processing therapy (CPT) is an effective treatment for individuals diagnosed with PTSD. CPT–Cognitive (CPT‐C) is a modified form of CPT. This case report describes a 12‐week course of CPT‐C treatment, enhanced to address heavy alcohol use, in a combat veteran with PTSD and co‐occurring AD. By treatment end, the veteran demonstrated clinically significant improvement in both PTSD symptoms and alcohol‐related problems and sustained these gains 12‐weeks posttreatment. The results indicate promise for the use of CPT‐C, enhanced for heavy alcohol use, for individuals diagnosed with PTSD and AD.
Deoximation by cetyltrimethylammonium dichromate: A kinetic study
Authors: Sahu Sandhyamayee , Patel Sabita , Mishra Bijay K 
Published: July 2011

AbstractThe deoximation kinetics of some oximes was studied by using cetyltrimethylammonium dichromate (CTADC) in dichloromethane in the presence of acetic acid and a cationic surfactant. The rate of reaction is highly sensitive to the change in [CTADC], [oxime], [acid], [surfactant], polarity of the solvents, and reaction temperature. The reaction is found to be catalyzed by acid with an appreciable uncatalytic rate. The reaction is first order with respect to substrate. With increase in CTADC concentration, rate of the reaction increases with a fractional order dependency with respect to oxidant. Consistent to the observation, a mechanism has been proposed in which the substrate forms a complex with CTADC in the rate determining step followed by decomposition with a fast process to yield corresponding carbonyl compounds. The structure of the substituents has also a significant effect on the rate constant. © 2011 Wiley Periodicals, Inc. Int J Chem Kinet 43: 482–488, 2011
Kinetic study of the interaction of three glycine‐containing dipeptides with diaquaethylenediamineplatinum(II) in aqueous medium
Authors: Mallick Subhasis , Mondal Subala , Mandal Arup , Bera Biplab K. , Karmakar Parnajyoti , Ghosh Alak K. 
Published: July 2011

AbstractThe kinetics of the interaction of three glycine‐containing dipeptides, namely, glycine‐L‐leucine (Gly‐Leu), glycine‐L‐isoleucine (Gly‐Ile), and glycine‐valine (Gly‐Val) with [Pt(en)(H2O)2](ClO4)2 has been studied spectrophotometrically as a function of [substrate complex], [dipeptides] and temperature at a particular pH(4.0), where the substrate complex exists predominantly as the diaqua species and the dipeptides as a zwitterion. The substitution reaction shows two consecutive steps; the first is the ligand‐assisted anation and the second is the chelation step. The activation parameters for both the steps were evaluated using Eyring's equation. The low ΔH1≠ and large negative value of ΔS1≠ as well as ΔH2≠ and ΔS2≠ indicate an associative mode of activation for both the aqua ligand substitution processes. © 2011 Wiley Periodicals, Inc. Int J Chem Kinet 43: 498–506, 2011
Kinetics and mechanism of the reaction of propylene oxide with chlorine atoms and hydroxy radicals
Authors: Middala Srikar , Campbell Sean , Olea Catalina , Scruggs Austen , Hasson Alam S. 
Published: July 2011

AbstractThe kinetics and mechanism of gas‐phase propylene oxide (PPO) reactions were studied in a 142‐L reaction chamber by long‐path Fourier transform infrared spectroscopy at atmospheric pressure and 298 K. Rate coefficients for the reaction of PPO with ozone (O3), chlorine atoms (Cl), and hydroxyl radicals (OH) were measured using the relative rate technique. Product yields of acetic acid, acetic formic anhydride, formic acid, and carbon monoxide were determined for the following reactions: PPO with Cl both in the presence and absence of NO, PPO with OH and NO, methyl acetate with Cl both in the presence and absence of NO, and ethyl formate with Cl both in the presence and absence of NO. The measured rate coefficients for PPO with O3, Cl, and OH are <3.5 × 10−21 cm3 molecule−1 s−1, (3.0 ± 0.7) × 10−11 cm3 molecule−1 s−1, and (3.0 ± 1.0) × 10−13 cm3 molecule−1 s−1, respectively. The carbon balance for the products measured ranged from 10% (for OH + PPO) to 100% (for Cl + methyl acetate in the absence of NO). The mechanistic and atmospheric implications of these measurements are discussed. © 2011 Wiley Periodicals, Inc. Int J Chem Kinet 43: 507–521, 2011
Coherent state transforms attached to generalized Bargmann spaces on the complex plane
Authors: Mouayn Zouhaïr 
Published: July 2011

AbstractWe construct a family of coherent states transforms attached to generalized Bargmann spaces [C. R. Acad. Sci. Paris, t. 325, 1997] in the complex plane. This constitutes another way of obtaining the kernel of an isometric operator linking the space of square integrable functions on the real line with the true‐poly‐Fock spaces [Oper. Theory, Adv. Appl. v. 117, 2000]. © 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
19%‐efficient and 43 µm‐thick crystalline Si solar cell from layer transfer using porous silicon
Authors: Petermann Jan Hendrik , Zielke Dimitri , Schmidt Jan , Haase Felix , Rojas Enrique Garralaga , Brendel Rolf 
Published: July 2011

ABSTRACTWe present a both‐sides‐contacted thin‐film crystalline silicon (c‐Si) solar cell with a confirmed AM1.5 efficiency of 19.1% using the porous silicon layer transfer process. The aperture area of the cell is 3.98 cm2. This is the highest efficiency ever reported for transferred Si cells. The efficiency improvement over the prior state of the art (16.9%) is achieved by implementing recent developments for Si wafer cells such as surface passivation with aluminum oxide and laser ablation for contacting. The cell has a short‐circuit current density of 37.8 mA cm−2, an open‐circuit voltage of 650 mV, and a fill factor of 77.6%. Copyright © 2011 John Wiley & Sons, Ltd.
Nanoparticle‐enhanced light trapping in thin‐film silicon solar cells
Authors: Ouyang Zi , Zhao Xiang , Varlamov Sergey , Tao Yuguo , Wong Johnson , Pillai Supriya 
Published: July 2011

ABSTRACTA systematic investigation of the nanoparticle‐enhanced light trapping in thin‐film silicon solar cells is reported. The nanoparticles are fabricated by annealing a thin Ag film on the cell surface. An optimisation roadmap for the plasmon‐enhanced light‐trapping scheme for self‐assembled Ag metal nanoparticles is presented, including a comparison of rear‐located and front‐located nanoparticles, an optimisation of the precursor Ag film thickness, an investigation on different conditions of the nanoparticle dielectric environment and a combination of nanoparticles with other supplementary back‐surface reflectors. Significant photocurrent enhancements have been achieved because of high scattering and coupling efficiency of the Ag nanoparticles into the silicon device. For the optimum light‐trapping scheme, a short‐circuit current enhancement of 27% due to Ag nanoparticles is achieved, increasing to 44% for a “nanoparticle/magnesium fluoride/diffuse paint” back‐surface reflector structure. This is 6% higher compared with our previously reported plasmonic short‐circuit current enhancement of 38%. Copyright © 2011 John Wiley & Sons, Ltd.
Additional coating effects on textured ZnO : Al thin films as transparent conducting oxides for thin‐film Si solar cells
Authors: Moon Taeho , Jun Jin Hyung , Lee Hyun , Yoon Wonki , Kim Soohyun , Lee Byung‐Kee , Lee Hong‐Cheol , Kim Wooyoung , Ahn Seh‐Won , Lee Sungeun , Lee Heon‐Min 
Published: July 2011

ABSTRACTZnO : Al films were additionally deposited on textured transparent conducting oxide thin films to improve the surface morphologies formed in the etching process. The efficiency of the µc‐Si : H cell was enhanced from 7.0% (uncoated) to 8.0% (150‐nm‐coated) because of the additional coating. The quantum efficiency evaluation with a reverse bias voltage showed that the additional coating suppressed the carrier recombination problem. To systematically analyze the change of the i‐layer quality, the changes of (μτ)eff and fill factor (FF) were analyzed using a variable illumination measurement technique, and the results clearly confirmed the enhancement of i‐layer quality due to the additional coating. Copyright © 2011 John Wiley & Sons, Ltd.
Skin care behaviors among melanoma survivors
Authors: Bowen Deborah , Jabson Jennifer , Haddock Nicole , Hay Jennifer , Edwards Karen 
Published: July 2011

AbstractIntroductionClinical recommendations for survivors of melanoma generally include skin care behaviors, including regular physician and skin self‐examination to identify any recurrences or second primary disease early, as well as sun protection. We measured skin care behaviors in a population‐based sample of melanoma survivors.MethodsMelanoma survivors were approached through the regional National Cancer Institute‐funded cancer registry (Surveillance, Epidemiology, and End Results) and recruited to this study with a response rate of approximately 75%, for a total sample of n = 313.ResultsThe sample was 99% Caucasian, 56% female, 44% male, 81% married, 62% college educated, and 48% with an income over 70 K annually, with an average age of 56 years. Over the last 7 days, a total of 45% reported wearing sunscreen, 59% reported wearing long sleeves, 80% reported wearing pants, 35% reported wearing something on the head, and 36% stayed in available shade. Skin self‐examination behaviors were reported at relatively low frequencies, with only 22% performing a thorough check on skin. A total of 88% of survivors reported that their physician checked their skin in the past few years by having all clothes removed. A multivariate analysis using logistic regression indicated that perceived risk was positively related to having the skin checked by a medical provider but no other skin protection behaviors. Gender effects were also detected for wearing sunscreen and wearing a hat or scarf.DiscussionData indicate that melanoma survivors are performing sun protection behaviors to a moderate extent. Future studies can address barriers to consistent use of these behaviors in melanoma survivors.Copyright © 2011 John Wiley & Sons, Ltd.
Rational designs of crystal solid‐solution materials for lithium‐ion batteries
Authors: Luo Ting , Zhang Caixia , Zhang Zhiyong , Zhu Yingdan , Li Jun 
Published: July 2011

AbstractWe present a new strategy for computer‐aided rational design of quantum supercells of crystal solid‐solution (SS) materials for lithium‐ion batteries. Layered SS materials Li(NixCoyMn1−x−y)O2 are used to demonstrate our design strategy. Crystal structures obtained by rational design agree well with those fully optimized by quantum total‐energy calculations and real materials measured from experiments. Compared with conventional first‐principles determination of structures, our approach achieves a significant increase in efficiency without loss of reliability and predictability for searching new structures. We further discuss the necessary steps to develop a generic strategy to rationally design new composite electrode materials.