bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunohistochemical Localization of Platelet‐Derived Growth Factor Receptors in the Porcine Uterus During the Oestrous Cycle and Pregnancy
Authors: Rodriguez‐Martinez H. , Persson E. , Hurst M. , Stanchev P. 
Published: May 2010

SummaryThe distribution of α‐ and β‐type receptors for PDGF was studied immunohistochemically in the uterus of cycling and pregnant pigs with well‐documented hormonal status in order to determine a possible steroid hormone‐dependence of its expression. Peroxidase‐antiperoxidase (PAP) labelling at light microscopical level was done with rabbit polyclonal antisera recognizing either both α‐ and β‐type receptors (PDGFR‐1), or selectively β‐type (PDGFR‐3). Immunoreactivity to the PDGF‐receptors of α‐ and β‐type (PDGFR‐1) was present in all endometrial samples examined, being located principally on subepithelial stromal and endothelial cells, the wall of endometrial blood vessels and in the fetal placenta (trophoblast and adjoining blood capillaries). In the myometrium, the major reactive cells were the non‐vascular smooth muscle cells, and to some extent, also those of the tunica media of major uterine vessels. No dramatic variations in the intensity of the reaction were noticed during the oestrous cycle. A very intense immunoreactivity was present at early pregnancy and at term, i. e. under major oestrogenic influence. The immunoreactivity to the PDGF‐receptor antiserum R‐3 (against β‐type) was similarly localized as that showed for R‐1 antiserum, while of a weaker intensity. The results indicate the presence of PDGF receptors (α‐ and β‐type) in the endo‐ and myometrium of cycling and pregnant pigs, and that their expression seems to be accentuated under oestrogenic influence.
Die Frischmasse sowie die Konzentration an DNA, RNA und Protein in verschiedenen Geweben von Schweinen unterschiedlichen Alters
Authors: Marx D. , Kolb E. , Salomon F.V. 
Published: May 2010

SummaryThe Wet Weight and the Concentration of DNA, RNA and Protein in Different Tissues of Pigs of Various AgeFemale pigs aged between one day (body weight 1.39 ± 0.20 kg) and 1123 days (b. w. 233 ± 32 kg) were allotted to 10 groups of various age and analyses of the concentration of DNA, RNA and protein in 9 different tissues were performed. The wet weight: DNA‐, the protein: DNA‐ and the RNA: DNA‐ratio were determined. With the exception of the liver the content in DNA, RNA and protein increased to the age of 1123 days. The highest fresh weight: DNA ratio of 2041 was reached on the 1123rd day in the M. longissimus; the smallest (111) existed at this time in the spleen. In the liver the highest content in fresh weight, in DNA and RNA was found on the 180th day. The smallest increases in the content of DNA and RNA in the mentioned period were in the brain, the highest in the spleen, the liver and the M. longissimus dorsi. The values can be used as a basis for studies on the influence of feeding and of diseases (infections) on growth.ZusammenfassungBei weiblichen Schweinen im Alter von einem Tag (KM: 1,39 ± 0,20 kg) bis zu einem solchen von 1123 Tagen (KM: 233 ± 32 kg) wurden in 10 Gruppen verschiedenen Alters Analysen der Konzentration an DNA, RNA und Protein in 9 verschiedenen Geweben durchgeführt. Die Frischmasse: DNA‐, die Protein: DNA‐ und die RNA: DNA‐Quotienten wurden ermittelt. Der Gehalt der meisten Gewebe — mit Ausnahme der Leber — an DNA, RNA und Protein nahm bis zum 1123. Tag zu. Der größte FM: DNA‐Quotient von 2041 wurde am 1123. Tag im M. longissimus erreicht; der kleinste (111) lag zu diesem Zeitpunkt in der Milz vor. In der Leber wurde der höchste Gehalt an Frischmasse, an DNA und RNA am 180. Tag ermittelt. Die niedrigsten Zunahmen im Gehalt an DNA und RNA im genannten Zeitraum lagen im Gehirn, die höchsten in der Milz, in der Leber und im M. longissimus dorsi vor. Die Werte können als Basis für Analysen über den Einfluß unterschiedlicher Fütterung und von Erkrankungen (Infektionen) auf das Wachstum verwendet werden.
Comparison of Staple and Suture Techniques for Partial Typhlectomy in the Cow: A Prospective Clinical Study of 40 Cases
Authors: Steiner A. , Braun U. , Waldvogel A. 
Published: May 2010

SummaryTwo techniques for partial typhlectony were evaluated on 20 cows each suffering from dilatation/torsion of the cecum. In a preliminary study on two cows the suitability of a stainless steel staple pattern using two TA 90 cartridges of 4.8 mm and 3.5 mm staples respectively was examined and the technique standardized. In the main clinical study the stapling pattern (group I) was compared with a simple continuous full thickness appositional suture oversewn with a continuous Cushing suture (group II).The cartridges with the 4.8 mm staples were used in 7 clinical cases, with intestinal wall edema and the 3.5 mm staples were used in 13 cases. Arterial bleeding from the cecal stump occurred in 20 out of 22 cases (including the results of the preliminary study). The number of arteries that had to be ligated was statistically significantly higher (p < 0.05) with the 4.8mm staples than with the 3.5mm staples. The additional ligation of bleeding vessels prolonged the surgical procedure. Seventeen out of 20 cows (85%) of each group were discharged from the clinic. The duration of the hospital stay was 6 days for both groups. Fourteen cows (70%) of each group were still alive upon inquiry. One cow of the stapling group was slaughtered because of a severe fibrinous peritonitis at the resection site. In the other 11 cows there was no evidence of a connection between the surgery and the slaughtering.
Haemodynamic Responses Following Meperidine and Promazine Induced Neuroleptanalgesia in Calves
Authors: Dass L.L. , Sahay P.N. 
Published: May 2010

SummaryInduction of neuroleptanalgesia in 6 calves by i/v administration of a combination of meperidine (@ 12 mg/kg body weight) and promazine (@ 3 mg/kg body weight) elicited various haemodynamic responses. The MAP and CVP exhibited significant (p < 0.01) overall variations with fluctuating fall and rise at different observation periods. A significant (p < 0.01) rise could be observed in HR which manifested a maximum and an abrupt rise (104.31%) at 5 minutes postinjection. Cardiac output, cardiac index, stroke volume, stroke index and total peripheral resistance exhibited significant (p < 0.01) overall variations with an initial fall in their values as compared to the respective base values. The cardiac output and cardiac index showed an alternate fall and rise from the preceeding value while the stroke volume, stroke index and total peripheral resistance manifested decreased values throughout the observation period as compared to base value. The values of all parameters measured, except heart rate, stroke volume, stroke index and total peripheral resistance, nearly returned to preinjection level by 120 minutes.
A Possible Role of Endotoxins in Spontaneous Paretic Cows Around Parturition
Authors: Aiumlamai S. , Fredriksson G. , Kindahl H. , Edqvist L.‐E. 
Published: May 2010

SummarySix late pregnant old cows which had a history of parturient paresis were studied with respect to clinical and blood biochemical changes during two weeks before and after parturition. The levels of serum endotoxin were evaluated during two days before and after parturition. Three out of six animals showed signs of paresis and two animals needed treatment. The clinical and general changes of all parameters supported the idea that during parturient paresis and parturition, there is absorption of endotoxins from the gastro‐intestinal tract. Most of the studied parameters changed similarly to what has been described in experimentally induced endotoxaemia. The animals showed signs of ruminal stasis, had an increase in body temperature, prostaglandin metabolite and endotoxin as well as a decrease in serum calcium, zinc, iron and bile acids levels. The changes of these parameters were also closely related to each other. Furthermore, the changes were more pronounced in paretic cows. Endotoxins absorbed from the gastro‐intestinal tract can be involved in paresis and make the outcome of this disease more severe.
Synovial Sarcoma in a Dog
Authors: Karayannopoulou M. , Kaldrimidou E. , Dessiris A. 
Published: May 2010

SummarySynovial sarcoma is an uncommon malignant tumour of mesenchymal origin, occurring mainly in the vicinity of a joint. Subsequent invasion of the joint and adjacent bones may occur. Less frequently the tumour may be localized in soft tissues remote from joints.Synovial sarcoma usually affects male middle‐aged dogs of large breeds. The rate of tumour growth can vary from very slow to very rapid. The tumour is usually poorly defined and infiltrates the deeper structures. Metastasis and recurrence are common. Wide‐field surgical excision of the tumour or amputation of the affected limb are the most frequently used forms of treatment.In the present case the dog, a 7‐year‐old male Alsatian, had a slowly growing tumour in the vicinity of the hip joint, bilaterally. There was no involvement of the bones surrounding the tumour. Surgical resection was performed and one year later the dog was reported to be normal.
Über den Einfluß einer unterschiedlichen Energieversorgung wachsender Doggen auf Körpermasse und Skelettentwicklung
Authors: Meyer H. , Zentek J. 
Published: May 2010

SummaryInfluence of various levels of energy intake on development of body weight and skeleton in growing Great Danes 1. Growth rate and energy requirement27 Great Danes (from 3 litters) were fed ad lib. (n = 9) or with an energy intake (n = 18) restricted to 80 and 70% of the paired ad lib. group, respectively, and a nearly equalized protein and nutrient supply meeting the current recommendations (8 dogs of the restricted groups were bearing weight loaded [15% of own BW] belts in the scapular region).Dogs were weighed weekly, shoulder height, approximate length of the forearm and foot were recorded in certain intervalls. In plasma protein, urea, Ca, P, Cu, Zn, and alkaline phosphatase were determined. Intake of digestible energy (according to the results of digestive trials) was recorded daily.Zusammenfassung27 Doggen (aus 3 Würfen) wurden ad lib. (n = 9) oder restriktiv (n = 18) aufgezogen (Energieaufnahme 80 bzw. 70% der ad lib. gefütterten Gruppe) bei annähernd gleich hoher, bedarfsgerechter Eiweiß‐ und Nährstoffzufuhr in beiden Gruppen (die Hälfte der restriktiv gefütterten Tiere mit Gewichtsbelastung; 15% der KM).Die Hunde wurden regelmäßig gewogen, gemessen (Widerristhöhe, Unterarm‐ und Fußlänge) und zu Blutanalysen herangezogen (Plasmaeiweiß, Harnstoff, Ca, P, Cu, Zn, alkalische Phosphatase). Die Aufnahme an verd. Energie (bestimmt durch Verdauungsversuche) wurde täglich registriert.
Hereditary Peromelia in Mohair Goats
Authors: Nielsen J.S. , Arnbjerg J. 
Published: May 2010

SummaryThe occurrence of a new congenital defect of the appendicular skeleton in Mohair goats is described. The malformation is peromelia and occurs in a familiar pattern. The defect seems to have an autosomal recessive mode of inheritance with variation in the expressivity of the genotype. The pathological abnormalities were described in 8 cases, all characterized by agenesia of the phalanges and parts of the metacarpus or metatarsus affecting one or more limbs. In some cases additional skeletal defects were found. Furthermore, 5 cases were reported by the owners with a description of the limb affected and 1 case was examined clinically. Predisposition for pelvic limbs to be affected was observed. The defect, which does not seem to have been described in goats previously, is phenotypically similar to and possibly also genetically homologous to a defect described in sheep.
Gross and Histopathological Observations on the Effects of Therapeutic Ultrasound in Experimental Acute Chemical Arthritis in Calves
Authors: Bhatia R. , Sobti V.K. , Roy K.S. 
Published: May 2010

SummaryAcute chemical arthritis was induced in right radiocarpal joints of eight cow calves by intraarticular injections of turpentine oil. They were randomly divided into two groups A and B of four calves each. Group A served as control. Group B was given therapeutic ultrasound @2.0W/cm2for 7 minutes daily for 7 days starting on day 5. On day 19, all the calves of both the groups were slaughtered. Grossly as well as microscopically, joint tissues of group A calves showed severe inflammatory and degenerative changes. Joint capsule of group B calves showed regeneration of synovial membrane and articular cartilage was normal grossly as well as microscopically.
Cardiorespiratory Parameters in Draught Horses before and after Short Term Draught Work Pulling Loads
Authors: Pérez R. , Recabarren S. E. , Mora G. , Jara C. , Quijada G. , Hetz E. 
Published: May 2010

SummaryIn order to establish the relationship between draught force and cardiorespiratory responses to exercise heart rate (HR), respiratory rate (RR), arterial and venous blood gases, pH, hemoglobin concentration and temperature were measured in five draught horses during rest, immediately after exercise and 30 min post‐exercise under field conditions. A wagon equipped with an odometer and a hydraulic dynamometer was used for measuring distance and draught force. The wagon was loaded with 946 kg for the low load, 1, 979 kg for the medium load and 2,994 kg for the high load, and drawn for a distance of 1,500 m. Draught force and load weight were linearly related. The response of the draught horse to low and medium load exercise was characterized by a moderate increase in HR, RR and temperature with no significant changes in arterial blood gases and pH. An increase in HR, RR and temperature was observed, whereas no changes in arterial PO2and increases in venous PO2were noticed after high load exercise. Slight increase in venous lactic acid concentration as a result of high load exercise was observed, suggesting that some anaerobic work was performed. However this was insufficient to produce changes in blood pH. The increase in metabolic requirements during the three levels of draught exercise was associated with increases in arterial hemoglobin concentration and oxygen content of blood.
Registrierung des Freßverhaltens beim frei beweglichen Tier am Beispiel der freitauchenden Weddellrobbe* (Leptonychotes Weddellii)
Authors: Bornemann H. , Mohr E. , Plötz J. 
Published: May 2010

SummaryMonitoring the feeding behaviour on freely diving Weddell seals (Leptonychotes weddellii)During the antarctic summer 1990, the pattern of food intake in comparison to diving‐activity was investigated on adult Weddell seals. Diving depths were recorded by a time‐depth recorder (TDR). The TDR is a free programmable electronic datalogger, which can store data on up to 5 channels. It was fixed on the fur of the seal, ensuring that no longer lasting irritation of the animal was caused.The pattern of food‐intake was monitored by measuring the jaw‐movements, using strain gauges for recording the deformation of the muscles by mastication. After electronic amplification and filtering, the frequency of jaw‐activity within a measuring period was recorded one channel of the TDR. By simultaneously observing the diving depths, these data may lead to conclusions about chewing patterns of the seal in water depths where they catch prey.The graph of these data and the mathematical evaluation by Fourier analysis and Plexogramme show a close correlation between diving depth and jaw‐activity.ZusammenfassungIm Rahmen eines Forschungsprojektes des AWI sollte das Freßverhalten der Weddellrobbe untersucht werden. Hierzu wurde ein elektronischer Datenspeicher (TDR) benutzt, der frei programmierbar auf bis zu 5 Kanälen Meßwerte speichern kann. Dieses Gerät wird extracorporal so befestigt, deß eine anhaltende Beeinträchtigung für das Tier ausgeschlossen wird. Zur Registrierung der Freßaktivität wurde eine Methode entwickelt, bei der die Verformung der Kaumuskulatur mit Hilfe von Dehnungsmeßstreifen (DMS) registriert wird. Nach elektronischer Verstärkung und Filterung kann so die Häufigkeit der Kieferbewegungen innerhalb eines Meßintervalles registriert werden. Simultan dazu wurde auf einem weiteren Kanal die Tauchtiefe registriert. Sowohl die grafische Darstellung der Meßwerte als auch eine mathematische Auswertung mit Hilfe der Fourier‐Analyse und des Plexogramms zeigen einen engen Zusammenhang zwischen Tauchtiefe und Kieferaktivität.
Atlanto‐occipital Fusion in two Polled Hereford Calves
Authors: Engelken T.J. , Leipold H.W. , Spire M.F. , Cash W.C. 
Published: May 2010

SummaryTwo cases of atlanto‐occipital fusion were diagnosed in Polled Hereford calves. The cause, genetic or environmental, of this abnormality could not be determined. Since relatively minor traumatic forces during birth can cause severe injury in the head region, atlanto‐occipital fusion should be ruled out in calves dying acutely after assisted parturition.
The Effects of Medroxyprogesterone Acetate and Ethinylestradiol on Hemogram, Prostate, Testes, and Semen Quality in Normal Dogs
Authors: Bamberg‐Thalén Birgitta , Linde‐Forsberg Catharina 
Published: May 2010

SummaryThree dogs were treated with medroxyprogesterone acetate (MPA) and three were treated with ethinylestradiol. The results indicate that at a dosage of 3–4.8 mg/kg b. w. MPA does not have any detrimental effects on hemogram, testicles or semen quality, whereas ethinylestradiol (2 μg/kg b. w. / day) can negatively affect both testes and semen quality. Both drugs can cause a decrease in prostatic size in clinically healthy dogs. Measurements of peripheral serum testosterone levels indicate that at the dosages used, testosterone levels are depressed considerably more by ethinylestradiol than by MPA.
Electron Microscopy of the Endometrium of Camels in Normal and some Diseased Conditions
Authors: Fetaih H. , Pospischil A. , Waldvogel A. 
Published: May 2010

SummaryUltrastructure of the camel's endometrium in normal and diseased conditions, was studied using the electron microscope. The samples were obtained from 6 normal uteri and 10 uteri with inflammatory lesions. Three ovaries of the latter 10 uteri showed ovarian cysts. All the animals were non‐pregnant. No cyclic changes were taken in consideration because the camel is an induced ovulator animal.The surface and the glandular epithelium of the normal uteri consisted of one layer of tall columnar cells, resting on an undulating membrane. The free borders of cells showed microvilli, motile cilia and zeiotic blebs. Desmosomes and gap junctions were seen as means of connections between the neighboring cells. The nuclei were large, oval and situated in the lower half of the cells. Two types of mitochondria were seen. One type was small, rounded and dilated, and the other was large and elongated. Many lipid droplets and scanty glycogen granules were common findings in the normal cells. Granulated bodies similar to those described in the epithelium of the human uterus and containing acid phosphatase were found. Many other cytoplasmic organelles and granules were seen. The endometrial stroma consisted mainly of stromal cells of irregular shape, and collagen fibres. The collagen fibres were present in amounts larger than many other species.In the diseased uteri, the changes in the epithelium consisted mainly of hyperplasia of the cells and marked increase of all cytoplasmic inclusions and vacuoles. There was also marked increase in the number of the crossing lymphocytes through the epithelial layer. The collagen fibres of the stroma increased in amount and the stromal cells became similar in shape to the fibroblasts. A large number of mast cells as well as other types of inflammatory cells infiltrated the stroma. Non‐specific bacterial infections were detected on bacteriological examination of the inflammed uteri. Neither bacteria nor other microbial agents could be seen ultrastructurally. In an uterus associated with ovarian cysts, the microvilli of its epithelium showed marked changes in their shape and length.
Histologische Untersuchungen einer zungenförmigen Zubildung am Sulcus intertubercularis im Schultergelenk des Hundes
Authors: Rapp E. , Lechleitner E. , Plenk H. 
Published: May 2010

SummaryHistological investigation of a tongue‐shaped bone formation at the intertubercular groove of the canine shoulder jointRadiologically apparent unilateral changes at the intertubercular groove of the humerus were investigated histologically in three dogs and compared with the findings in an unaltered shoulder joint of a dog. Polymethylmethacrylate embedded, undecalcified sections were cut through the sulcus area at the head of humerus and through the biceps tendon, its synovial sheet and the transverse ligament, and were evaluated by light microscopy.While the tendon and soft tissue features were for the most part typical for a normal “gliding” tendon, the respective groove exhibited an again groove‐like, 10–12 mm wide and up to 2 mm high exostosis consisting mainly of lamellar bone, filled with hemopoetic and fatty marrow. The normal fibrocartilaginous lining of the groove showed degenerative arthrotic changes in the altered grooves, pointing to mechanical overloading. The possible mechanisms of these ossifications are discussed.ZusammenfassungIn der vorliegenden Arbeit wurden die radiologisch erkennbaren einseitigen Veränderungen am Sulcus intertubercularis der Bizepssehne von drei Hunden histologisch untersucht und mit den Ergebnissen einer unveränderten Schulter eines Hundes verglichen. Dafür wurden in Polymethyl‐methacrylat eingebettete unentkalkte Dünnschnitte durch den Humeruskopf in Höhe des Sulcus intertubercularis sowie von Bizepssehne, Sehnenscheide und Ligamentum transversum angefertigt und lichtmikroskopisch ausgewertet.An den Weichteilen wurden vorwiegend physiologische Befunde im Sinne einer Gleitsehne erhoben. Im veränderten Sulcusbereich aller drei Hunde wurde ein zungenförmiger, 10–12 mm breiter bis 2 mm hoher, knöcherner Zubau aus großteils lamellärem Knochen mit hämatopoetischem Knochenmark und Fettmark gefunden. Die üblicherweise mit Faserknorpel ausgekleidete Gleitfurche zeigte bei den betroffenen Gelenken degenerative arthrotische Veränderungen, die auf mechanische Überbelastung hinweisen. Mögliche Entstehungsmechanismen für den Knochenzubau werden diskutiert.
Inhibition of Food Intake and Reticulo‐Rumen Motility of Sheep by the Alpha‐2 Adrenoreceptor Agonist Clonidine
Authors: Nicholson T. , Osman T.E.A. 
Published: May 2010

SummaryThe investigation of the effect of intravenous clonidine, an alpha‐2 adrenoreceptor agonist, was carried out in sheep with recording of forestomach motility for 3 h and intake of chopped hay for 8 h after drug administration. Motility and food intake were inhibited by clonidine at 2 μg · kg−1and at 5 μg · kg−1. The effects of the lower dose were prevented by idazoxan, an alpha‐2 antagonist, at 0.1 mg · kg−1but not by prazosin, an alpha‐1 antagonist, at 0.1 mg · kg−1. Minor effects of the antagonists alone were noted. Blood glucose concentration was measured in all the experiments and the possibility discussed that changes in concentration, not absolute values, may have contributed to inhibitory effects. Vagal stimulation in anaesthetised sheep indicated that inhibition of motility was a central neural effect, not an effect on forestomach muscle.