bluuebunny/crossref_metadata_2025_split huggingface dataset:
Screening and analysis of the multiple absorbed bioactive components and metabolites in rat plasma after oral administration of Jitai tablets by high‐performance liquid chromatography/diode‐array detection coupled with electrospray ionization tandem mass spectrometry
Authors: Wang Shu‐Ping , Liu Lei , Wang Ling‐Ling , Jiang Peng , Zhang Ji‐Quan , Zhang Wei‐Dong , Liu Run‐Hui 
Published: May 2010

AbstractBased on the serum pharmacochemistry technique and high‐performance liquid chromatography/diode‐array detection (HPLC/DAD) coupled with electrospray tandem mass spectrometry (HPLC/ESI‐MS/MS), a method for screening and analysis of the multiple absorbed bioactive components and metabolites of Jitai tablets (JTT) in orally dosed rat plasma was developed. Plasma was treated by methanol precipitation prior to liquid chromatography, and the separation was carried out on a Symmetry C18 column, with a linear gradient (0.1% formic acid/water/acetonitrile). Mass spectra were acquired in negative and positive ion modes, respectively. As a result, 26 bioactive components originated from JTT and 5 metabolites were tentatively identified in orally dosed rat plasma by comparing their retention times and MS spectra with those of authentic standards and literature data. It is concluded that an effective and reliable analytical method was set up for screening the bioactive components of Chinese herbal medicine, which provided a meaningful basis for further pharmacology and active mechanism research of JTT. Copyright © 2010 John Wiley & Sons, Ltd.
Robotic hip arthroscopy in human anatomy
Authors: Kather Jens , Hagen Monika E. , Morel Philippe , Fasel Jean , Markar Sheraz , Schueler Michael 
Published: May 2010

AbstractBackgroundRobotic technology offers technical advantages that might offer new solutions for hip arthroscopy.MethodsTwo hip arthroscopies were performed in human cadavers using the da Vinci© surgical system. During both surgeries, a robotic camera and 5 or 8 mm da Vinci trocars with instruments were inserted into the hip joint for manipulation.ResultsIntroduction of cameras and working instruments, docking of the robotic system and instrument manipulation was successful in both cases. The long articulating area of 5 mm instruments limited movements inside the joint; an 8 mm instrument with a shorter area of articulation offered an improved range of motion.ConclusionsHip arthroscopy using the da Vinci standard system appears a feasible alternative to standard arthroscopy. Instruments and method of application must be modified and improved before routine clinical application but further research in this area seems justified, considering the clinical value of such an approach. Copyright © 2010 John Wiley & Sons, Ltd.
Stability criteria for uncertain stochastic dynamic systems with time‐varying delays
Authors: Kwon O. M. 
Published: May 2010

AbstractIn this paper, the problem of delay‐dependent stability for uncertain stochastic dynamic systems with time‐varying delay is considered. Based on the Lyapunov stability theory, improved delay‐dependent stability criteria for the system are established in terms of linear matrix inequalities. Three numerical examples are given to show the effectiveness of the proposed method. Copyright © 2010 John Wiley & Sons, Ltd.
Airborne vision‐based mapping and classification of large farmland environments
Authors: Bryson Mitch , Reid Alistair , Ramos Fabio , Sukkarieh Salah 
Published: May 2010

AbstractThis paper presents a framework for integrating sensor information from an inertial measuring unit (IMU), global positioning system (GPS) receiver, and monocular vision camera mounted to a low‐flying unmanned aerial vehicle (UAV) for producing large‐scale terrain reconstructions and classifying different species of vegetation within the environment. The reconstruction phase integrates all of the sensor information using a statistically optimal nonlinear least‐squares bundle adjustment algorithm to estimate vehicle poses simultaneously to a highly detailed point feature map of the terrain. The classification phase uses feature descriptors based on the color and texture properties of vegetation observed in the vision data and uses the terrain information to build a georeferenced map of different types of vegetation. The resulting system can be used for a range of environmental monitoring missions such as invasive plant detection and biomass mapping. Experimental results of the algorithms are demonstrated in a “weed‐finding” mission over a large farmland area of the Australian outback. © 2010 Wiley Periodicals, Inc.
A cross‐layer framework for IPsec over satellite links
Authors: Roseti C. , Luglio M. , Fairhurst G. , Ramachandran S. 
Published: May 2010

AbstractThe traditional modular OSI‐layered architecture has served a major role in the development of a variety of protocols. However, as physical layer impairments become complex and time varying, a dynamic cross‐layer design can enable better performance. A Cross‐Layer Architecture (CLA) is proposed to improve performance of error‐tolerant applications running over UDP‐Lite. This approach to implementation introduces new challenges in protocol design, as well as in the area of security, where the study proposes a new method to enable IP security (IPsec) authentication and integrity services at the network layer. Target scenarios include satellite multicast for large‐scale delivery of data and video content. In this scenario, CLA can mitigate the effects of physical layer impairments and high latency. Numerical analysis has shown that a link design employing header compression and cross‐layer signalling may protect protocol headers and can reduce the probability of packet discard. To evaluate the feasibility of the CLA, these methods have been implemented as an extension to the IPsec protocol, named Cross‐Layer IPsec (CL‐IPsec). A satellite emulation platform was used to validate the implementation of CL‐IPsec and to evaluate the overall performance improvement resulting from the proposed CLA. Copyright © 2010 John Wiley & Sons, Ltd.
Experience with Delay‐Tolerant Networking from orbit
Authors: Ivancic W. , Eddy W. M. , Stewart D. , Wood L. , Northam J. , Jackson C. 
Published: May 2010

AbstractWe describe the first use from space of the Bundle Protocol for Delay‐Tolerant Networking (DTN) and lessons learned from experiments made and experience gained with this protocol. The Disaster Monitoring Constellation (DMC), constructed by Surrey Satellite Technology Ltd (SSTL), is a multiple‐satellite Earth‐imaging low‐Earth‐orbit sensor network in which recorded image swaths are stored onboard each satellite and later downloaded from the satellite payloads to a ground station. Store‐and‐forward of images with capture and later download gives each satellite the characteristics of a node in a disruption‐tolerant network. Originally developed for the ‘Interplanetary Internet,’ DTNs are now under investigation in an Internet Research Task Force (IRTF) DTN research group (RG), which has developed a ‘bundle’ architecture and protocol. The DMC is technically advanced in its adoption of the Internet Protocol (IP) for its imaging payloads and for satellite command and control, based around reuse of commercial networking and link protocols. These satellites' use of IP has enabled earlier experiments with the Cisco router in Low Earth Orbit (CLEO) onboard the constellation's UK‐DMC satellite. Earth images are downloaded from the satellites using a custom IP‐based high‐speed transfer protocol developed by SSTL, Saratoga, which tolerates unusual link environments. Saratoga has been documented in the Internet Engineering Task Force (IETF) for wider adoption. We experiment with the use of DTNRG bundle concepts onboard the UK‐DMC satellite, by examining how Saratoga can be used as a DTN ‘convergence layer’ to carry the DTNRG Bundle Protocol, so that sensor images can be delivered to ground stations and beyond as bundles. Our practical experience with the first successful use of the DTNRG Bundle Protocol in a space environment gives us insights into the design of the Bundle Protocol and enables us to identify issues that must be addressed before wider deployment of the Bundle Protocol. Published in 2010 by John Wiley & Sons, Ltd.
The relevance of ecocentrism, personal development and transformational leadership to sustainability and identity
Authors: Hay Robert 
Published: May 2010

AbstractIdentity is formed gradually as we mature through personal development within societal (and natural) context. As such, it is group informed but individually directed and is strongly influenced by our family, community, place and natural surroundings. Together, these interwoven aspects of our lives help us each to create an identity that is unique and that should be able to be sustained over time. However, because we live within collectives and places that have often become less sustainable of late, this has a corresponding effect on our identity. The interactive relationship between identity and sustainability is therefore integral to how we understand and then address issues that currently confront us all. To investigate this relationship, three aspects of identity are considered together: the significance of an ecocentric philosophy, personal development oriented to service and transformational leadership. Interweaving these related reflections goes beyond a more limited view of identity, providing new directions for sustainability. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Unstable identities: stable unsustainability
Authors: Strannegård Lars , Dobers Peter 
Published: May 2010

AbstractThe identity concept has emerged as a key analytical concept in the social sciences in the past decades. In both scientific accounts and everyday use, the identity concept has traditionally been seen as something that individuals possess. This view has however been heavily criticized by a social identity strand of social science, where identity is a matter of a negotiation where different social roles are learned in relations with others. The relational view of identities creates some serious problems for the sustainability challenge. In a world of relational identities, individuals are engaged in identity‐creating interactions every day. Key problems are that the interactions, in urban environments, are highly commercialized; consumption cues are emotionally based and speak to our senses, and outnumber the competing cues several times over. Sustainable lifestyles are thus very fragile. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
The surface profile and biocompatibility of hydroxyapatiteblasted gold membrane as a periodontal guided tissue regeneration membrane
Authors: Jin Kangsik , Youn Lee Doug , Je Jina , Keun Lee Yong , Nam Kim Kyoung , Mahn Kim Kwang 
Published: May 2010

AbstractGuided tissue regeneration (GTR) membrane is essential for periodontal surgery, GTR membrane can guide successful bone tissue formation. The aim of this study is to assess morphologic property and biocompatibility of hydroxyapatite (HA) blasted gold membrane as a periodontal GTR membrane. 99.99 gold (LS Nikko, Korea) was rolled to 0.025∼0.050 mm thickness, and then, blasted with hydroxyapatite powder (5 ∼ 25 µm, Ossgen, Korea) onto the rolled gold sheets. Contact angle measurement of non‐blasted and HA‐blasted surface was performed. And, scanning electron microscopy analysis (simple surface profile observation and observation after attachment of human osteosarcoma cell) was performed. In implantation test using adult dog, Ti‐membrane (Implantium, Suwon, Korea) was used as a control group, and HA‐blasted gold membrane was used as a experimental group. Contact angle of HA‐blasted gold membrane was higher than that of non‐blasted gold surface (p < 0.05). In SEM analysis, HA‐blasted gold membrane showed roughened surface and attachment of MG‐63 cell was more than that of non‐blasted gold surface. There were not any specific clinical symptoms and histological signs in implantation test. This result shows that HA‐blasted gold membrane has a possibility as promising periodontal GTR membrane. Copyright © 2010 John Wiley & Sons, Ltd.
Effect of temperature on free β‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A concentration
Authors: Cruz J. , Cruz G. , Minekawa R. , Maiz N. , Nicolaides K. H. 
Published: May 2010

AbstractObjectiveTo examine the effect of the duration of storage of serum and whole blood at different controlled temperatures on the concentrations of both serum free‐β‐human chorionic gonadotropin (β‐hCG) and pregnancy‐associated plasma protein‐A (PAPP‐A) in first‐trimester screening for aneuploidies.MethodsThe concentrations of free β‐hCG and PAPP‐A were measured in samples collected from 10 pregnant women and stored as whole blood or serum for 1–8 days at 4, 20 or 40 °C. The concentrations measured were adjusted to take day‐to‐day variations into account and were expressed as a percentage of the values on day 0. In a second study involving 10 pregnant women, free β‐hCG was measured at 10 min and at 2, 4, 8 and 12 h after collection and storage at 30 or 40 °C, either as separated serum or as whole blood.ResultsThe change in the levels of PAPP‐A in the separated serum at all three temperatures and in whole blood at 4 °C was always less than 10% throughout the 8 days of storage. In whole blood stored at 20 and 40 °C, the percentage variation was less than 10% only if the storage period was shorter than 4 days. The concentration of free β‐hCG was not altered by storage of either whole blood or separated serum at 4 °C throughout the 8 days of storage. At 20 °C, reliable results were obtained only if the maximum storage time was 2 days for separated serum and 1 day for whole blood. At 30 °C, reliable results were obtained only if the samples were analyzed within 2 h of collection, and at 40 °C the concentrations increased by more than 50% within 2 h and by about 500% after 1 day of storage.ConclusionIn first‐trimester screening for aneuploidies, analysis of blood samples should be undertaken within a few minutes of collection, otherwise the samples should be refrigerated at 4 °C throughout the interval between collection and analysis. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Value of transvaginal ultrasound in assessing severity of pelvic endometriosis
Authors: Holland T. K. , Yazbek J. , Cutner A. , Saridogan E. , Hoo W. L. , Jurkovic D. 
Published: May 2010

AbstractObjectiveThe objective of this study was to examine the ability of preoperative transvaginal ultrasound (TVS) scanning to assess the severity of pelvic endometriosis.MethodsConsecutive women with clinically suspected or proven pelvic endometriosis, who were booked for laparoscopy, were invited to join the study. The severity of endometriosis was assessed preoperatively using TVS and the findings were compared with the results obtained by laparoscopy using the American Society for Reproductive Medicine (ASRM) classification.ResultsIn total, 201 women had preoperative TVS and laparoscopies. Of these, no endometriosis was found at laparoscopy for 62/201 (30.8%; 95% CI, 24.8–37.5), whereas 33/201 (16.4%; 95% CI, 11.9–22.2) had minimal endometriosis, 31/201 (15.4%; 95% CI, 11.1–21.1) had mild endometriosis, 27/201 (13.4%; 95% CI, 9.4–18.8) had moderate endometriosis and 48/201 (23.9%; 95% CI, 18.5–30.2) had severe endometriosis. The sensitivity and specificity of the TVS diagnosis of severe pelvic endometriosis were 0.85 (95% CI, 0.716–0.934) and 0.98 (95% CI, 0.939–0.994), respectively, and the positive and negative likelihood ratios were 43.5 (95% CI, 14.1–134) and 0.15 (95% CI, 0.075–0.295), respectively. Overall, there was a good level of agreement between ultrasound and laparoscopy in identifying absent, minimal, mild, moderate and severe disease (quadratic weighted kappa = 0.786). The mean ASRM score difference between TVS and laparoscopy in assessing severity of endometriosis was − 2.398 (95% CI, − 4.685 to − 0.1112) and the limits of agreement were − 34.62 (95% CI, − 38.54 to − 30.709) to 29.83 (95% CI, 25.91–33.74).ConclusionsTVS is a good test for assessing the severity of pelvic endometriosis. TVS is particularly accurate in detecting severe disease, which could facilitate more effective triaging of women for appropriate surgical care. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Infant categorization
Authors: Rakison David H. , Yermolayeva Yevdokiya 
Published: May 2010

AbstractIn this article, we review the principal findings on infant categorization from the last 30 years. The review focuses on behaviorally based experiments with visual preference, habituation, object examining, sequential touching, and inductive generalization procedures. We propose that although this research has helped to elucidate the ‘what’ and ‘when’ of infant categorization, it has failed to clarify the mechanisms that underpin this behavior and the development of concepts. We outline a number of reasons for why the field has failed in this regard, most notably because of the context‐specific nature of infant categorization and a lack of ground rules in interpreting data. We conclude by suggesting that one remedy for this issue is for infant categorization researchers to adopt more of an interdisciplinary approach by incorporating imaging and computational methods into their current methodological arsenal.WIREs Cogn Sci2010 1 894–905This article is categorized under:Psychology > Development and Aging
Perception and action
Authors: Creem‐Regehr Sarah H. , Kunz Benjamin R. 
Published: May 2010

AbstractThe phrase perception and action is used widely but in diverse ways in the context of the relationship between perceptual and motor processes. This review describes and integrates five perspectives on perception and action which rely on both neurophysiological and behavioral levels of analysis. The two visual systems view proposes dissociable but interactive systems for conscious processing of objects/space and the visual control of action. The integrative view proposes tightly calibrated but flexible systems for perception and motor control in spatial representation. The embodied view posits that action underlies perception, involving common coding or motor simulation systems, and examines the relationship between action observation, imitation, and the understanding of intention. The ecological view emphasizes environmental information and affordances in perception. The functional view defines the relationship between perception, action planning, and semantics in goal‐directed actions. Although some of these views/approaches differ in significant ways, their shared emphasis on the importance of action in perception serves as a useful unifying framework. WIREs Cogn Sci 2010 1 800–810This article is categorized under:

Psychology > Motor Skill and Performance
Light detection and ranging measurements of wake dynamics. Part II: two‐dimensional scanning
Authors: Trujillo Juan‐José , Bingöl Ferhat , Larsen Gunner C. , Mann Jakob , Kühn Martin 
Published: May 2010

AbstractA nacelle‐mounted lidar system pointing downstream has been used to measure wind turbine wake dynamics. The new measurement and data analysis techniques allow estimation of quasi‐instantaneous wind fields in planes perpendicular to the rotor axis. A newly developed wake tracking procedure delivers the instantaneous transversal wake position which is quantitatively compared with the prediction of the Dynamic Wake Meandering model. The results, shown for two 10‐min time series, suggest that the conjecture of the wake behaving as a passive tracer is a fair approximation; this corroborates and expands the results of one‐dimensional measurements already presented in the first part of this paper. Consequently, it is now possible to separate the deterministic and turbulent parts of the wake wind field, thus enabling capturing the wake in the meandering frame of reference. The results correspond, qualitatively and to some extent quantitatively, to the expectations from CFD simulations which are compared in the paper. Copyright © 2010 John Wiley & Sons, Ltd.
Functional interactions between mRNA turnover and surveillance and the ubiquitin proteasome system
Authors: Brooks Seth A. 
Published: May 2010

AbstractThe proteasome is a critical regulator of protein levels within the cell and is essential for maintaining homeostasis. A functional proteasome is required for effective mRNA surveillance and turnover. During transcription, the proteasome localizes to sites of DNA breaks, degrading RNA polymerase II and terminating transcription. For fully transcribed and processed messages, cytoplasmic surveillance is initiated with the pioneer round of translation. The proteasome is recruited to messages bearing premature termination codons, which trigger nonsense‐mediated decay (NMD), as well as messages lacking a termination codon, which trigger nonstop decay, to degrade the aberrant protein produced from these messages. A number of proteins involved in mRNA translation are regulated in part by proteasome‐mediated decay, including the initiation factors eIF4G, eIF4E, and eIF3a, and the poly(A)‐binding protein (PABP) interacting protein, Paip2. eIF4E‐BP (4E‐BP) is differentially regulated by the proteasome: truncated to generate a protein with higher eIF4B binding or completely degraded, depending on its phosphorylation status. Finally, a functional proteasome is required for AU‐rich‐element (ARE)‐mediated decay but the specific role the proteasome plays is unclear. There is data indicating the proteasome can bind to AREs, act as an endonuclease, and degrade ARE‐binding proteins. How these events interact with the 5′‐to‐3′ and 3′‐to‐5′ decay pathways is unclear at this time; however, data is provided indicating that proteasomes colocalize with Xrn1 and the exosome RNases Rrp44 and Rrp6 in untreated HeLa cells. Copyright © 2010 John Wiley & Sons, Ltd.This article is categorized under:

RNA Turnover and Surveillance > Turnover/Surveillance Mechanisms
RNA Turnover and Surveillance > Regulation of RNA Stability
Translation > Translation Mechanisms
BaNi2Ge and Ca4Ni4Ge3 – Two layered Structures with $\rm ^2_\infty$[Ni2Ge] and, $\rm ^2_\infty$[Ni4Ge3] Networks
Authors: Siggelkow Lisa , Hlukhyy Viktor , Fässler Thomas F. 
Published: May 2010

AbstractThe intermetallic compounds BaNi2Ge and Ca4Ni4Ge3 were prepared by melting stoichiometric amounts of the elements in welded tantalum ampoules in an induction furnace. The compounds were investigated by both powder and single‐crystal X‐ray diffraction. Both compounds crystallize in own structure types, BaNi2Ge with space group Pmmn, a = 6.6935(5) Å, b = 4.1571(5) Å, c = 5.9498(7) Å, wR2 = 0.043, 292 F2 values, 16 variable parameters; Ca4Ni4Ge3 with space group Cmcm, a = 4.1824(8) Å, b = 10.415(2) Å, c = 19.864(4) Å, wR2 = 0.061, 541 F2 values, 38 variable parameters., The chemical bonding of these compounds is discussed in terms of TB‐LMTO‐ASA calculations and a topological analysis of the Electron Localization Function (ELF).
1‐Amino‐2‐fluoromonocarba‐closo‐dodecaborates: K[1‐H2N‐2‐F‐closo‐1‐CB11H10] and [Et4N][1‐H2N‐2‐F‐closo‐1‐CB11I10]
Authors: Finze Maik , Sprenger Jan A. P. 
Published: May 2010

AbstractThe potassium salt of the [1‐H2N‐2‐F‐closo‐1‐CB11H10]– anion (1) was obtained from an insertion reaction of Li3[7‐H2N‐nido‐7‐CB10H10] with BF3·OEt2. Anion 1 was protonated to the neutral species 1‐H3N‐2‐F‐closo‐1‐CB11H10 (H1) and it was iodinated with ICl to the [1‐H2N‐2‐F‐closo‐1‐CB11I10]– anion (2). All species were characterized by multinuclear NMR, IR, and Raman spectroscopy as well as by elemental analysis. The structure of H1·(CH3)2CO was studied by single‐crystal X‐ray diffraction and the experimentally determined bond lengths are compared to values derived from density functional calculations.