bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical and experimental study on the critical geometric variation based on sensitivity analysis on a compressor rotor
Authors: Wang Yan , Zhu Mingmin , Zhang Songan , Qiang Xiaoqing , Zheng Biaojie , Teng Jinfang 
Published: June 2024

Abstract
Different types of geometric variations often appear coupledly in manufactured blades. It is desired to identify the ones that have the strongest impact on the performance. In this paper, the influence of multiple geometric variations on the compressor rotor blade at the design point is studied. Two hundred and nine varied blades are constructed by adding variation data to the design-intent blade and assessed using steady-state Reynolds-Averaged Navier–Stokes (RANS) simulations. It is shown that the region near the lower and upper end of the blade is more sensitive to geometric variations. Spearman’s rank correlation coefficient is used to measure the sensitivity of rotor performance to geometric variations. The results show that the stagger angle variation is the most influencing variation. Local sensitivity analysis at different spans also shows that the stagger angle variation is an important geometric variation that needs more attention during blade manufacturing. Also, the influence of geometric variations can reach further than nearby regions. Consequently, experiments on linear cascades at different spans of the rotor are carried out to study the effect of stagger angle on flow characteristics. Results show that the stagger angle variation could lead to different changes in performance depending on the specific cascade profile.
Morphological and immunological characterization of primary cultured chicken caecal epithelial cells
Authors: Willer Thomas , Kaiser Annette , Smith Adrian , Rautenschlein Silke 
Published: June 2024

AbstractCell cultures are models in biological and medical research to understand physiological and pathological processes. Cell lines are not always available depending on cell type and required species. In addition, the immortalization process often affects cell biology. Primary cells generally maintain a greater degree of similarity in short-term culture to the cells in tissue. Goal of this study was to verify the suitability of chicken primary epithelial caecal cells (PECCs) for in vitro investigations of host‒pathogen interactions. Epithelial nature of PECCs was confirmed by detection of tight and adherens junctions and cobblestone-like cell morphology. Sialic acids distribution was similar to that in caecal cyrosections. To understand the capacity of PECCs to respond to microbial challenges, the Toll-like receptors (TLRs) repertoire was determined. Exposure of PECCs to polyinosinic-polycytidylic acid (poly(I:C)) or lipopolysaccharide (LPS) led to upregulation of type I and III interferon (IFN) as well as interleukin (IL-) 1β, IL-6 and IL-8 mRNA expression. Overall, the PECCs showed properties of polarized epithelial cells. The presence of TLRs, their differential expression, as well as pattern recognition receptor dependent immune responses enable PECCs to act as suitable in vitro model for host‒pathogen interaction studies, which are difficult to conduct under in vivo conditions.
Pensamiento Matemático de Estudiantes de Quinto Grado cuando Inventan y Solucionan Problemas
Authors: Castro Walter F. , Herrera-Restrepo Catalina 
Published: June 2024

El artículo indaga sobre el pensamiento matemático manifestado por estudiantes de quinto grado, cuando inventan y resuelven problemas matemáticos. El problema de investigación refiere al desconocimiento del pensamiento matemático de los estudiantes y cómo se suele infravalorar cuando se hace mediante pruebas estandarizadas. Conocer el pensamiento matemático de los estudiantes ayuda a construir procesos de estudio que los reconozca. La investigación se realizó durante un año, es cualitativa y naturalista, se utilizó la invención y solución de problemas para determinar tanto el pensamiento matemático de los estudiantes como estrategias de solución. Los registros se tomaron de la producción escrita de cuarenta niños de quinto grado, cuando inventaron problemas para ser propuestos y resueltos por sus compañeros. Los resultados informan que los niños inventan problemas de naturaleza aritmética, prefieren las operaciones entre números sobre las relaciones entre ellos, y manifiestan dificultades para proponer problemas cuando se les da información.
Disparity in temporal and spatial relationships between resting-state electrophysiological and fMRI signals
Authors: Tu Wenyu , Cramer Samuel , Zhang Nanyin 
Published: June 2024

Abstract

Resting-state brain networks (RSNs) have been widely applied in health and disease, but the interpretation of RSNs in terms of the underlying neural activity is unclear. To address this fundamental question, we conducted simultaneous recordings of whole-brain resting-state functional magnetic resonance imaging (rsfMRI) and electrophysiology signals in two separate brain regions of rats. Our data reveal that for both recording sites, spatial maps derived from band-specific local field potential (LFP) power can account for up to 90% of the spatial variability in RSNs derived from rsfMRI signals. Surprisingly, the time series of LFP band power can only explain to a maximum of 35% of the temporal variance of the local rsfMRI time course from the same site. In addition, regressing out time series of LFP power from rsfMRI signals has minimal impact on the spatial patterns of rsfMRI-based RSNs. This disparity in the spatial and temporal relationships between resting-state electrophysiology and rsfMRI signals suggests that electrophysiological activity alone does not fully explain the effects observed in the rsfMRI signal. To reconcile this disparity, we propose a model hypothesizing that a significant component of the rsfMRI signal is driven by neural activities that are not directly captured by electrophysiology, yet are active in neurovascular coupling. These "electrophysiology-invisible" signals exhibit weak temporal correlation with electrophysiology data. However, due to the shared anatomical backbone constraining both types of neural activities, they can produce similar spatial patterns in RSNs in parallel. These findings, along with our proposed model, offer a novel perspective on our understanding of RSN interpretation.
Concurrent infection of Babesia canis vogeli and Ehrlichia canis in a non-descriptive Indian dog
Authors: Sharma Maneesh , Kumar Tarun , Kumar Aman , Kumar Sanjay , Lata Sneh , Sharma Shalini , Jain V K 
Published: June 2024

Abstract

The present study reports a complicated case of co-infection by haemoprotozoan and haemorickettsiale in a two months old non descriptive male dog. The aim of present clinical study includes early diagnosis of complicated infections to make the prognosis safe. For confirmatory diagnosis, blood sample was collected for routine haemato-biochemical, blood smear examination and molecular diagnosis. Dog had history of vomition and anorexia since last one week. Clinical examination of animal revealed dullness, depression, pale conjunctival mucus membrane and decreased rectal temperature (96.20F). Haematological investigation revealed severe anaemia, neutrophilic leukocytosis and thrombocytopenia. Biochemical examination revealed increased plasma levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), Blood urea nitrogen (BUN), hyperbilirubinemia, hypoglycemia, hypoproteinemia and hypoalbuminemia. Microscopic examination of blood smear revealed oval to pyriform bodies in groups as Babesia canis in RBC’s as well as outside the RBC’s and morula of Ehrlichia canis within the cytoplasm of monocyte. Blood sample was also processed for molecular diagnosis and confirmed positive for both the infections by PCR method. Haemato-biochemical alterations; microscopic examination and molecular diagnosis by PCR confirmed the coinfection of Babesia canis vogeli and Ehrlichia canis in affected dog and proved the infection fatal and can make the prognosis grave. Treatment was given to animal but unfortunately animal was died on the same day. Hence, the present study concludes the confirmatory diagnosis of coinfection of Babesia canis vogeli and Ehrlichia canis in dogs.
A relational approach to co-create Advance Care Planning with and for people living with dementia: a narrative study
Authors: Phenwan Tharin , Sixsmith Judith , McSwiggan Linda , Buchanan Deans 
Published: June 2024

Abstract

Background
Discussing Advance Care Planning (ACP) with people living with dementia (PwD) is challenging due to topic sensitivity, fluctuating mental capacity and symptom of forgetfulness. Given communication difficulties, the preferences and expectations expressed in any ACP may reflect family and healthcare professional perspectives rather than the PwD. Starting discussions early in the disease trajectory may avoid this, but many PwD may not be ready at this point for such discussions. Consequently, the optimal timing to discuss an ACP with and for PwD is undetermined. This study explored the changing needs of PwD and experiences of social contexts that influence ACP initiation and revision and aimed to identify the optimal time to discuss an ACP with PwD.
Methods
Narrative online and telephone interviews were conducted with 13 PwD and 23 family carers. Participants were recruited via the Join Dementia Research (JDR) Platform. Narrative analysis was used to identify patterns in the data, generating three narratives: Shifting Expectations; Relational Interdependency and Trigger Points.
Results
The Shifting Expectations narrative indicated that PwD’s needs shifted to co-constructed needs with their family as PwD’s independence declined. This was reflected in the Relational interdependency narrative where PwD almost always co-created and revised their ACPs with trusted key persons who provided relational support. The Trigger points narrative indicated various points in time when PwD can effectively initiate and revise their ACPs, ranging from before the diagnosis to years afterwards, challenging the current suggestion of an early ACP initiation.
Conclusions
This study highlighted the changing co-constructed needs between PwD and their families that influence how PwD initiate and revise their ACP. The identification of ACP trigger points - the pivotal events throughout the dementia journey - that prompt PwD and family members to discuss their ACPs were suggested, indicating that PwD can initiate and revise their ACPs throughout the disease trajectory provided relational support is available whereby key persons involved in their care are involved and agree with the decisions being made. Therefore, an alternative, relational approach to ACP with and for PwD is recommended.
The Ecological Tapestry of Lonar Crater: Biodiversity, Conservation Challenges, and Preservation Strategies of the Ecosystem
Authors: Dighe Bhushan B. , Singh M. R. , Ragde Rajesh , Maurya Satish 
Published: June 2024

Abstract

The Lonar Crater, a geological marvel located in Buldana District of India’s Maharashtra state, stands as a unique testament to Earth's natural history, formed around 30,000-50,000 years ago by a meteorite impact on Deccan Plateau basalts. The floral and faunal study of Lonar Lake is a comprehensive research endeavor aimed at understanding the biodiversity and ecological dynamics of this unique ecosystem. The study covered various significant points around the lake spanning a total distance of 3.2 km (aerial) and then back to the Lonar Lake entry point. The main objective of this study was to investigate the occurrence of native flora and fauna and to assess the impact of introduced species on the native biodiversity of the area. This study deals into the diverse flora and fauna of the Lonar ecosystem, revealing 85 plant species, including natives, naturalized, and introduced varieties, alongside a rich avian and reptilian fauna. However, presently the ecosystem faces challenges, including invasive species, deforestation, and pollution. This research underscores the urgency of conservation efforts to protect Lonar's ecological balance and preserve its unique biodiversity.
Comparison of RSM, ANN, and ANFIS in predicting the weld strength of Laser transmission welds of oak wood powder-reinforced polypropylene absorbent part.
Authors: Kapuyanyika Munyaradzi , Ude Albert Uchenna , Chinnasamy Vivekanandhan 
Published: June 2024

Abstract

This study examines the feasibility of Laser transmission welding(LTW) of a 100% homo-polypropylene transparent part joined to an absorbent part composed of 15% wt white oak wood fiber reinforced homo-polypropylene doped with 0.2% carbon black in lap-joint configuration. Focus is given to investigating the influence of process parameters, namely laser power, welding speed, stand-off distance, and clamp pressure on the laser welded joints of polypropylene joined to plant-based polypropylene composite and the feasibility of weld strength prediction using Response Surface Method (RSM), Artificial Neural Network (ANN) and Adaptive Neuro-Fuzzy Inference System (ANFIS). Results showed that stand-off distance was the most crucial factor affecting weld strength, followed by welding speed. Laser power and clamp pressure had insignificant effects on weld strength in the design space studied in this paper. The coefficient of determination (R2) was (0.90), (0.93), and (0.99) for the RSM model, the ANN model, and the ANFIS model, respectively. All the prediction models exhibited acceptable mean absolute error percentages and root-mean-square errors. The results suggested a satisfactory performance in predicting weld strength for the specified materials in this study's specified parameter design space. The ANFIS model showed the best predictions, followed by the ANN and RSM models.
The relationship between kindergarten teachers' emotional intelligence and classroom management ability: An investigative study with latent profile analysis
Authors: Di Huijuan , Lun Yuting , Zhang Beibei 
Published: June 2024

Abstract

Objective
To explore the potential categories of preschool teachers' emotional intelligence and its influence on classroom management ability, and to provide a theoretical basis for improving preschool teachers' classroom management ability. Methods: In March, 2023, 496 preschool teachers from all districts and counties in Hebei Province were selected by cluster sampling, and a cross-sectional survey was conducted by using the Emotional Intelligence Scale and the Classroom Management Ability Scale. The potential profile analysis is used to construct different potential categories of emotional intelligence, and the influence of emotional intelligence on classroom management ability was analyzed by multiple linear regression. Results: There are three potential types of emotional intelligence of preschool teachers: low emotional intelligence (20.8%), medium emotional intelligence (59.9%) and high emotional intelligence (20.8%). There are significant differences in the EQ level of preschool teachers in the aspects of teachers' age, marital status, kindergarten types and locations. Compared with low emotional intelligence group, middle emotional intelligence group and high emotional intelligence group can positively predict classroom management ability (β = 0.39, 0.75; p <. 001); The organization of teaching activities for classroom management ability (β = 0.41, 0.76; p <. 001), teacher-child interaction (β = 0.36, 0.71; p <. 001), creating a classroom environment (β = 0.36, 0.73; p <. 001), order maintenance (β = 0.16, 0.30; p <. 001), children's participation (β = 0.29, 0.72; p <. 001) has a positive predictive function. Conclusion: There are three potential categories of preschool teachers' emotional intelligence, which have a positive predictive effect on classroom management.
Sociodemographic and Ocular Factors Associated with Glaucoma ER Care: A Retrospective Analysis from an Eye Emergency Room
Authors: Shukla Aakriti , Ramesh Sunidhi , Abishek Robert , Cherkas Elliot , Shalaby Wesam , Zhang Qiang (Ed) , Chung Christine , Haqqie Nadie , Kolomeyer Natasha , Lee Daniel , Razeghinejad Reza , Myers Jonathan 
Published: June 2024

Abstract

Objective: To describe the demographic factors and clinical characteristics associated with the utilization of an eye emergency room resulting in glaucoma care referral.
Design: Retrospective cohort study.
Subjects: All patients seen at the Wills Eye Emergency Room (ER) from October 1, 2020, to March 31, 2021, who were referred for glaucoma care.
Methods and Measures: Demographic data were collected. Blindness in one or both eyes was defined as BCVA ≤20/200.1
Results: 7438 patients presented to the ER during the study period, and 192 (2.6%) were referred for glaucoma care. Of the 108 patients who provided ophthalmic history, 76 (70.4%) patients (40.8% unilaterally blind and 5.3% bilaterally blind) received a new diagnosis of definite or suspected glaucoma in the ER. 43 of 192 (22.4%) patients required urgent glaucoma procedural intervention after the ER visit; 28 (65.1%) were given a new diagnosis of definite or suspected glaucoma in the ER. 31 of 192 (16.2%) patients were uninsured; they were more likely to be younger in age (54.4 ± 14.5 years vs. 61.8 ± 15.7 years; P=0.016) and to speak a primary language other than English (16.1% vs. 5.6%; P=0.042) as compared to insured patients.
Conclusion: Over a 6-month period, glaucoma represented a small subset of ER visits but resulted in a new diagnosis of definite or suspected glaucoma in the majority of cases, of whom 46.1% were unilaterally or bilaterally blind. Almost two-thirds of those with a new diagnosis required an urgent glaucoma procedural intervention after the ER visit.
Investigating PCB degradation by Indigenous Fungal Strains Isolated from the Transformer Oil-Contaminated Site: Degradation Kinetics, Bayesian Network, Artificial Neural Networks, QSAR with DFT, Molecular Docking, and Molecular Dynamics Simulation
Authors: Singh Ningthoujam Samarendra , Mukherjee Irani 
Published: June 2024

Abstract

The widespread prevalence of polychlorinated biphenyls (PCBs) in the environment has raised major concerns due to the associated risks to human health, wildlife, and ecological systems. Here, we investigated the degradation kinetics, Bayesian Network (BN), Quantitative Structure-Activity Relationship-Density Functional Theory (QSAR-DFT), Artificial Neural Network (ANN), Molecular docking (MD) and Molecular dynamics stimulation (MS) of PCBs biodegradation i.e. PCB-10, PCB-28, PCB-52, PCB-138, PCB-153, and PCB-180 in the soil system using fungi isolated from the transformer oil-contaminated sites. Results revealed that the efficacy of PCBs biodegradation best fits the first-order kinetics (R2 ≥ 0.93). The consortium treatment (29.44–74.49%) exhibited more efficient degradation of PCBs than those of Aspergillus tamarii (27.09–71.25%), Corynespora cassiicola sp. MN69 (23.76–57.37%), and Corynespora cassiicola sp. MN70 (23.09–54.98%). 3'-methoxy-2, 4, 4'-trichloro-biphenyl as an intermediate derivative was detected in the fungal consortium treatment. The BN analysis predicted that the biodegradation efficiency of PCBs ranged from 11.6–72.9%. The ANN approach showed the importance of quantum chemical descriptors (QCD) i.e., LUMO > Molecular weight > Ionization Potential > No. of Chlorine > HOMU in PCBs removal. Furthermore, the QSAR-DFT model between the QCD and rate constant (Log K) exhibited a high fit and good robustness of R2 = 99.12% in predicting ability. The MD and MS analyses showed the lowest binding energy through Normal Mode Analysis (NMA), implying stability in the interactions of the docked complexes. These findings provide crucial insights for devising strategies focused on natural attenuation, holding substantial potential for mitigating PCBs contamination within the environment.
Deep Learning Approaches for COVID-19 Detection from CT Scans and Chest X-Rays: A Comparative Study of VGG, ResNet, Inception, and Xception Models
Authors: M Balaji , C Venkata Arun Kumar , S Ayyasamy 
Published: June 2024

Abstract

Accurate diagnosis of COVID-19 is critical for patient management and disease control. In this study, we evaluate the performance of Convolutional Neural Network (CNN) models, including VGG, ResNet, Inception, and Xception, for COVID-19 detection using CT scans and chest X-ray images. Leveraging deep learning algorithms and multiple layers such as Conv2D, MaxPooling2D, Flatten, and Dense, we analyze medical images to identify COVID-19 patterns. Through comprehensive dataset training and evaluation, we assess model accuracy, sensitivity, and specificity. Our findings highlight the potential of CNN-based approaches for accurate COVID-19 diagnosis from chest radiography images, contributing to the development of advanced diagnostic tools in combating the pandemic.
Application of multidisciplinary treatment in the diagnosis and treatment of patients with advanced colorectal cancer：a retrospective study in China
Authors: Li Zhenyu , Shang Manman , xue Mengqi , Huang Xinyu , Huang Shuyi , Chen Zhiping , Chen Jinhua , Wei Qin 
Published: June 2024

Abstract

Objective
Analyze the application and value of multidisciplinary treatment (MDT) for stage IV colorectal cancer patients and summarize work experience.
Methods
The clinical data of patients with stage IV colorectal cancer from January 2017 to December 2021 in the Department of Colorectal Surgery of the hospital were retrospectively analyzed. Patients who received MDT were included in the MDT group, and patients who did not receive MDT were included in the Non-MDT group. The basic information and follow-up data of the two groups were collected, and the general baseline data (including gender, age, pathological stage, primary tumor location, intestinal obstruction, number of metastatic organs, and location of metastasis) and the one-year, two-year, and three-year survival rates of the two groups were compared by chi-square test. The hospital stay and hospitalization cost of the two groups were compared by Z test. The survival curve was drawn by the Kaplan-Meier method, and the difference in overall survival rate between the two groups was compared by log-rank test.
Results
A total of 544 patients with stage IV colorectal cancer (staged according to the NCCN guidelines for clinical staging of tumors) were enrolled. There were no statistically significant differences in gender, age, pathological stage, primary tumor location, number of metastatic organs, metastatic sites, and intestinal obstruction between the two groups (P > 0.05). The hospital stay and hospitalization cost of the MDT group were lower than those of the Non-MDT group, and the differences were statistically significant (P < 0.05). The survival curve indicated that the overall survival cycle of the MDT group was longer than that of the Non-MDT group.
Conclusions
Most patients with advanced colorectal cancer are complicated cases. The multidisciplinary diagnosis and treatment service mode can improve the survival cycle of hospital stay of patients, and improve the operation efficiency of hospitals.
implications for Cancer Survivors
multidisciplinary treatment care enables cancer survivors to receive proper diagnosis and treatment, increases survival time, improves patients' quality of life, and reduces all costs.