bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion
Authors: Beeston Dave , Szladovits Balazs , Cortellini Stefano 
Published: May 2024

Abstract

OBJECTIVE
To describe the presentation, diagnosis, and treatment of 4 cases of splenic torsion with associated spherocytosis.

ANIMALS
4 client-owned dogs with spherocytosis and splenic torsion.

CLINICAL PRESENTATION
Each dog presented with nonspecific clinical signs, and 3 out of 4 dogs were anemic on presentation.

RESULTS
The diagnosis of splenic torsion was made with abdominal ultrasound or CT and confirmed during exploratory laparotomy. Spherocytosis was described as occasional (patient 1), rare (patient 2), and low number (patients 3 and 4). Two dogs survived to hospital discharge, and 2 dogs died following cardiorespiratory arrest.

CLINICAL RELEVANCE
Spherocytosis has not previously been reported in cases of splenic torsion, and identification of spherocytes on blood film evaluation warrants further investigation. The cause of spherocytosis in splenic torsion remains unknown but may be associated with microangiopathic fragmentation injury.
Technological challenges in manufacturing of vacuum gauge thermionic cathode using thick-film technology
Authors: Jasińska Laura , Dzbik Krzysztof , Nowak Damian , Stojek Krzysztof , Chudzyńska Aleksandra , Politański Kamil , Malecha Karol 
Published: May 2024

Abstract
This paper focuses on the development of a technological challenges of manufacturing the planar ceramic vacuum sensor based on the principles of hot-cathode ionization in the Bayard-Alpert configuration. The goal is to simplify the technological process by utilizing planar platinum structures with gold electrical paths instead of 3-dimensional structures. Various methods were tested, including the use of carbon-based SVM (Sacrifice Volume Materials) materials, but without success. Wet-etching using potassium hydroxide on Al2O3 substrates showed promise results. The findings highlight the challenges and progress made in developing the thermo-emittercomponent of the vacuum sensor.
The predictive validity of the Morse Fall Scale in hospitalized patients in the Czech Republic
Authors: Zeleníková Renáta , Jarošová Darja 
Published: May 2024

Abstract

Aim. The main aim of the study was to test the Morse Fall Scale (MFS) in the Czech population of hospitalized patients and to determine the predictive validity of the scale by assessing its specificity, sensitivity, positive predictive value, negative predictive value and cut-off points.

Material and methods. The study was a prospective follow-up study. Ten acute and long-term care units in two selected hospitals participated in the study. The sample consisted of 4383 patients. To assess the patients’ risk of falls, the MFS was chosen. The patients were assessed on admission.

Results. The reliability of the Morse Fall Scale measured by Cronbach’s alpha was 0.484. Using a cut-off point of 35, the sensitivity was 61.1% and the specificity was 53%. The positive predictive value was 10.5% and the negative predictive value was 90.6%.

Conclusions. Results of the study revealed only moderate predictive accuracy of the Morse Fall Scale.
Spirituality as an influential holistic factor in life satisfaction in older adults: descriptive research
Authors: Kaučič Boris Miha , Nedeljko Mihael , Filej Bojana 
Published: May 2024

Abstract

Aim. Life satisfaction is an important driver of life and an important factor in the personal stability of a person. With the research, we wanted to find which of the holistic factors is most related to life satisfaction in old age.

Material and methods. The research is based on the quantitative method of research, the method of description, compilation and causal non-experimental method. We used the survey technique. A total number of 656 older adults between the age of 65 and 98 participated in the survey. We obtained the data using various standardised measuring instruments. In order to determine the strength of the connection between holistic factors and life satisfaction in older adults, we used advanced statistical methods for the analysis of causal effects and conditional associations (propensity score methods).

Results. We found that the most important factor for life satisfaction in older adults is the spiritual factor (R²=0.37) and the self-esteem index (R²=0.488) within it. The spiritual factor is followed by a psychological factor (R²=0.21), social factor (R²=0.19) and finally the physical factor (R²=0.05).

Conclusions. Spirituality directs the lives of older adults and helps them to overcome various life problems. Since spirituality is a multidimensional concept, this research is an important starting point for further research in this field.
Duty of Civilians Security Agencies that Suffer Losses Due to Civil Corruption
Authors: Ginting Asepte Gaulle , Danil Elwi , Marlina  , Sukarja Detania 
Published: May 2024

Objective: The media at the time focused on corruption practices in Indonesia's BUMN sector. Weak supervisory functions by the BUMN Supervisory Body have led to inefficient oversight of the Directorate, which is one of the sources of corruption in the BUMN sector. Therefore, in the event that a loss results from corruption, the BUMN's supervisory bodies are required to assume criminal accountability.

Theoretical Framework: However, there are flaws and barriers in the application of criminal law that make it necessary to restructure the system of criminal responsibility against the supervisory bodies of the BUMN in order to impose criminal liability on them.

Method: A court decision that brings criminal accusations against Indonesian firms provided the data for this study. After identification under consideration and court ruling, a legal technique is used to assess the data and identify a solution to the issue.

Results and Conclusion: According to the study's findings, a supervisory body's failure to keep an eye on directors who engage in corrupt behavior is considered a "hole of omission," or a gap that puts the crime of inaction or passive acts in jeopardy.

Implication of the Research: This research will have an impact on law enforcement related to criminal acts of corruption against State-Owned Enterprises (BUMN).

Originality/Value: It is possible to create a just legal system where justice is the fundamental component of the law and the execution of the law itself by imposing criminal liability on supervisory authorities that fail to perform their oversight obligations against the Directorate in the management of BUMN.
Diagnosis with Guinea Pig (Cavia Porcellus), Aymara X-Rays and Treatment in Times Of COVID-19
Authors: Apaza-Ticona Jorge , Arocutipa Vicente Alanoca , Cutipa-Añamuro Guillermo , Calderón-Torres Alfredo , Chambilla-Laquiticona Adolfo , Maquera-Maquera Yuselino 
Published: May 2024

Objective: The objective is to identify the use and practice of diagnosis with Cuy (Cavia Porcellus), Aymara X-rays and treatment in Covid-19 times as a natural method different from the diagnostic and medication procedures of modern scientific biomedicine in this context. Theoretical framework: Traditional Aymara medicine is a current medical system practiced by peasant health agents, who still have a particular profile, where leadership, sensitivity, vocation, especially of service, stand out. It is still a system that responds to the health needs of the population. In the last two years, Aymara medicine resisted the Covid-19 pandemic with its own local resources, highlighting herbal medicine, the use of mineral and animal by-products in the diagnosis and treatment of post-Covid-19 patients. Method: This is an interpretative qualitative case study with ethnographic design through which the perceptions and practices of health restoration of doctors and Aymara patients affected by Covid-19 are analyzed. The research was conducted in the Aymara peasant communities of the provinces of Chucuito, El Collao and Puno in the districts of Acora, Chucuito and Pichacani, in the department of Puno (Peru) during the period 2021-2022. Results: The results show that ancestral Aymara medicine is an integral medical system that responds to a set of knowledge and know-how for the treatment of various physiological and cultural diseases. The guinea pig is important in traditional medicine, it is used as an "X-Ray" and has efficacy in the diagnosis, treatment, follow-up and prognosis of diseases caused by Covid-19 in the Aymara communities.
COVID-19 Pandemic and Impacts on the Environment in Brazil
Authors: Dutra Aline Soares de Santana , Passos Christian Ricardo Silva , Gomes Filho Teodoro Antunes , Nascimento Wanessa da Costa , Meller Guilherme Semprebom , Marques Francisco Roldineli Varela , Sousa Júnior Francisco Souto de , Gurgel Genilson Pereira , Lucena Raimundo de Oliveira , Santos Paulo Henrique Soles dos 
Published: May 2024

Objective: The objective of this research was to analyze the impacts of the Covid-19 pandemic on the environment in Brazil

Methodology: The research was conducted through an integrative review, using searches on Google Scholar and Scielo with specific keywords. Inclusion criteria were applied to select complete, free Brazilian scientific articles published between 2020 and 2023, excluding other types of studies. Data analysis involved two stages: reading abstracts and titles, followed by the complete reading of selected articles, resulting in a sample of four articles for analysis.

Results and data analysis: The COVID-19 pandemic represented an unprecedented event in contemporary history, causing profound impacts on human life. Through an analysis of available studies, it was possible to investigate the effects of this crisis on the environment. Initially, an opportunity was observed for a deep reflection on the complex interaction between these domains, evidenced by the significant temporary reduction in air and noise pollution and pressure on natural ecosystems, resulting from the slowdown in human activities. However, it is crucial to recognize the transitory nature of these benefits and the pressing need for a holistic and forward-looking approach to formulating policies and practices that promote environmental sustainability, contemplating not only the temporary reduction of human activity but also a reshaping fundamental aspect of society and the economy from an ecological and sustainable perspective. Furthermore, the importance of addressing the disproportionate impacts on vulnerable communities is highlighted, especially in the global and local context, as evidenced by the challenges faced by family farming in Brazil during the pandemic period.

Conclusion: It is concluded that environmental awareness and the adoption of sustainable practices emerge as crucial elements to face the challenges posed by the pandemic, requiring a review of consumption habits, investment in renewable energy and sustainable infrastructure, and promotion of environmental education.
Investigating the Use of Companion Animal Donor Tissue Banks
Authors: Mitchell Kaitlin , Carver L.F. 
Published: May 2024

Research and education continue to be highly reliant on the use of animal cadavers and tissues. However, due to the damaging impact on animal life, contribution to animal suffering, and lack of translatability of laboratory animal research to humans, alternatives must be investigated. An ethically sourced alternative is the use of non-human animal donor tissue banks, which involves the donation of companion animal cadavers and tissues. A scoping review of current research on the opinions pertaining to companion animal donor tissue banks was conducted using the Queen’s University Omni database. 62 articles were screened and three met the scoping review inclusion criteria. Collectively, these publications displayed positive attitudes among pet owners and veterinarian students towards companion animal cadaver and tissue donation. A common concern raised amongst participants of the studies was the inability to bury or cremate their pets if they were to donate them to tissue banks for research. In conclusion, this scoping review examined trends in the opinions of participants from several studies regarding the use of non-human animal donor tissue banks. Overall, companion animal tissue banks offer an ethical alternative to laboratory animal use and a more reliable model for translatability to humans. The gaps in knowledge outlined in this scoping review direct future research involving the collection of professional perspectives, including veterinarians and researchers.
The « Grands Moulins Vilgrain » (large Vilgrain mills) in Nancy: anonymization or (re)mobilization of a former industrial geosystem?
Authors: BARBIER Léopold 
Published: May 2024

À Nancy (France), se trouvent le long de la Meurthe les Grands Moulins. Il s’agit d’un ancien site industriel minotier, localisé à l’emplacement historique d’un moulin installé là depuis le XIIe/XIIIe siècle. Son nom, Grands Moulins, vient de la société qui a marqué durablement le site, les Grands Moulins Vilgrain. Cette entreprise a façonné le territoire nancéien en édifiant un bâtiment de production de neuf étages, devenu un marqueur paysager fort et créant autour de lui un géosystème industriel. Le site se trouve dans un ancien faubourg industriel en proie à de profondes reconversions depuis trente ans. Parce que son activité ne s’est arrêtée qu’en 2022, ce vaste site positionné au bord de l’eau a été épargné par les actions de renouveau urbain. L’arrêt récent de la production invite à se questionner sur les mobilisations faites de cet héritage industriel : quelle mémoire, quel patrimoine préserver ? Quels intérêts fonciers ? Quel(s) devenir(s) ? Après avoir analysé ce géosystème industriel, nous tenterons de saisir la multitude de ces enjeux.
Siciliano – Illustrations and Comment Fragments (to Hans Zender, to whom the “Dance Suite with a Song about Germany” is dedicated)
Authors: Лахенман Х.Ф. 
Published: May 2024

Настоящая публикация представляет собой перевод статьи Хельмута Лахенмана, которая посвящена анализу его собственной пьесы «Siciliano», являющейся одной из частей его «Танцевальной сюиты с песней о Германии» («Tanzsuite mit Deutschlandlied»). Первая публикация: Lachenmann H. Siciliano – Abbildungen und Kommentarfragmente («Tanzsuite mit Deutschlandlied») // Schweizerische Musikzeitung. 1983. Jg. 123. H. 6 (Nov./Dez. 1983). S. 348-356.
This publication presents a translation of Helmut Lachenmann’s article, which concerns the analysis of his own piece Siciliano, which is one of the parts of his Dance Suite with a Song about Germany (Tanzsuite mit Deutschlandlied). First publication: Lachenmann H. Siciliano – Abbildungen und Kommentarfragmente («Tanzsuite mit Deutschlandlied») // Schweizerische Musikzeitung. 1983. Jg. 123. H. 6 (Nov./Dez. 1983). S. 348-356.
RESTORASI CITRA MAGNETIC RESONANCE IMAGING (MRI) RUANG KATERISASI JANTUNG RSUD ULIN BANJARMASIN MENGGUNAKAN METODE BLIND DECONVOLUTION
Authors: Trianiza Ice - , Sidiq Abdurahim , Lisdawati Ayu Novia 
Published: May 2024

Magnetic Resonance Imaging (MRI) adalah sebuah metode pemeriksaan diagnostik yang mulai digunakan sejak tahun 1980. Gambar yang dihasilkan merupakan hasil rekonstruksi pencitraan komputer. Namun berbeda dengan CT-Scan MRI tidak menggunakan radiasi ion melainkan menggunakan medan magnet dan radiofrekuensi. studi kasus yang dijumpai banyak gangguan debluring terhadap citra yang didapatkan dari MRI. Degradasi dan gangguan tersebut tentunya akan berakibat pada pada kualitas gambar yang dihasilkan. Hal tersebut tentunya sangat merugikan dalam dunia medis dikarenakan citra yang dihasilkan akan digunakan untuk mendiagnosa ataupun mendeteksi kelainan yang ada pada tubuh. Dari hasil penulisan dapat disimpulkan proses peningkatan kualitas citra termal dilakukan dengan menggunakan metode blind deconvolution yang terdiri dari 3 tahap, yaitu mencari nilai kernel, mencari nilai konvolusi dan estimasi (MAP????,????). Metode blind deconvolution dapat diterapkan dalam peningkatan kualitas citra termal dengan cara mengurangi efek blur yang terdapat pada gambar. Aplikasi peningkatan kualitas citra termal telah selesai dirancang dengan menggunakan matlab R2022a dan dapat dijalankan pada sistem operasi macOS atau windows.
RANCANG BANGUN BRACKET SISTEM STEERING RODA DEPAN PADA PROTOTIPE MOBIL LISTRIK HEULANG GALUNGGUNG
Authors: Pratama Irfan Aditia 
Published: May 2024

Bracket sistem steering roda depan merupakan salah satu komponen kendaraan roda empat yang berfungsi sebagai penopang atau dudukan dari poros roda dan sistem kemudi.Penelitian ini bertujuan untuk mengetahui alur perancangan, proses manufaktur, serta pengujian dengan metode Finite Element Analysis. Perancangan gambar teknik (CAD), program NC (CAM), dan Finite Element Analysis (FEA) menggunakan software Solidworks dan proses manufaktur menggunakan mesin milling CNC. Hasil perancangan didapatkan jenis material yang digunakan adalah Alumunium 6061-T6. Proses pengujian menggunakan metode FEA dengan variasi beban 100 N, 125 N, dan 150 N. Beban maksimal 150 N didapatkan hasil pengujian menunjukan bahwa nilai Von mises stress adalah 438325,09 N/mm2, besar nilai displacement yang terjadi sebesar 0,000293 mm, nilai minimum safety factor adalah 125,86. Hasil yang didapatkan menunjukan bahwa bracket sistem steering roda depan yang didesain aman digunakan maksimal beban 150 N. Kata kunci : Bracket, CAD, CAM, FEA
Manejo odontológico de pacientes que tomen medicamentos anticoagulantes: revisión bibliográfica
Authors: Guayas Carrión Paola , Matute Merchán Sara 
Published: May 2024

Introducción: El manejo odontológico de pacientes que usan anticoagulantes es fundamental para prevenir eventos tromboembólicos con el riesgo de hemorragias. Objetivo: Determinar un protocolo adecuado del manejo odontológico de pacientes que tomen medicamentos anticoagulantes. Metodología: Estudio de revisión bibliográfica narrativa, con la búsqueda de estudios publicados durante 2017–2024. Se utilizaron palabras clave en PubMed, Scopus y Web of Science; el universo fue de 324 publicaciones y la selección final de 50 artículos. Resultados: El tiempo de protrombina se refleja en los resultados del índice internacional normalizado (INR). Los rangos seguros de INR para procedimientos odontológicos varían significativamente, siendo complementados por parámetros como: plaquetas, hemoglobina y hematocrito. Los anticoagulantes orales más frecuentes incluyen warfarina, dabigatrán, rivaroxabán y apixabán. Conclusiones: El manejo odontológico de pacientes anticoagulados, basado en una comprensión detallada de los rangos de INR, los parámetros hemáticos clave y las características específicas de los anticoagulantes orales, es esencial para minimizar los riesgos de hemorragia y asegurar tratamientos dentales seguros y efectivos.
КОРПОРАТИВНА СОЦІАЛЬНА ВІДПОВІДАЛЬНІСТЬ – ЗАПОРУКА СТАЛОГО РОЗВИТКУ БІЗНЕСУ
Authors: БАЙЛО Володимир 
Published: May 2024

Концепція корпоративної соціальної відповідальності значно еволюціонувала і стала важливим підґрунтям для наукових досліджень та формування державної політики економічного розвитку в різних країнах світу. Корпоративна соціальна відповідальність є невід'ємною складовою сучасного бізнесу. У статті розглянуто корпоративну соціальну відповідальність бізнесу, досліджено різні погляди щодо поняття «соціальна відповідальність», теоретичні та практичні аспекти корпоративної соціальної відповідальності, вплив корпоративної соціальної відповідальності на сталий розвиток підприємств. Проведено аналіз підходів до соціальної відповідальності та сформульовано основні причини впровадження практики корпоративної соціальної відповідальності. Досліджено практики соціальної відповідальності відомих компаній Nike, McDonald’s та Starbucks. Сформульовано основні кроки стратегії корпоративної соціальної відповідальності бізнесу в контексті його сталого розвитку.
Concordance and Acceptability of HPV DNA Genotyping Test by Patient’s Self-Sampling Against Clinician Sampling
Authors: Indarti Junita , Syaharutsa Danny Maesadatu , Surya Ilham Utama , Alda Kristian 
Published: May 2024

Objectives: To determine the effectiveness of this alternative method, especially during the COVID-19 pandemic and considering Indonesia’s cultural context.
Methods: This study utilized a cross-sectional design, and involved patients at the Gynecology and Colposcopy Clinic of Dr. Cipto Mangunkusumo General Hospital. The estimated sample size was 48, determined using a diagnostic test formula. The sample population consisted of female patients with positive VIA or abnormal Pap smear results. Each patient underwent HPV DNA self-sampling and clinician sampling tests using the GenoFlow HPV Array technique and continued with colposcopy. All patients were also administered a questionnaire consisting of eight questions about their perspective on the self-sampling HPV DNA test. The data analysis employed a 2 × 2 table using SPSS version 20, and Cohen’s kappa coefficient was calculated to measure the agreement between the sampling results of patients’ and Clinicians’.
Results: Among the examinations conducted by clinicians, there were 33 patients with positive HPV results, whereas through self-sampling, there were 28 patients with positive HPV (p=0.00). High risk HPV was the most commonly observed, with HPV type 16 appearing the most (15%). Based on these data, the self-sampling sensitivity, specificity, positive predictive value, and negative predictive value were 85%, 100%, 100%, and 75%, respectively, with a concordance rate of 89.6%. The Cohen’s Kappa coefficient between samples taken by the clinician and self-sampling resulted in K=0.778, which is considered a good agreement (K=0.61-0.80). All patients concluded that the procedure was easy (100%), and the majority (60.5%) expressed a preference for the self-sampling method.
Conclusion: There is a good agreement between the results of self-sampling and clinician sampling for detecting HPV DNA, with patients positively accepting the self-sampling method, indicating its potential as an effective cervical cancer screening method.
Keywords: Cervical Cancer Screening, Clinician Sampling, Human Papillomavirus, Self-Sampling.
The economic impact of 14 compassionate use programs for medicines in Italy, in the perspective of the National Health Service
Authors: Jommi Claudio , Pantellini Federico , Giuliani Giovanni , Cavazza Marianna 
Published: May 2024

Background: Compassionate use programs (CUP) for medicines allow patients, not recruited in trials, accessing medicines before marketing approval. The evidence on the economic impact of CUP is limited to one paper that did not include the possible long-term economic impact of medicines used in CUP compared to alternative treatments, like avoided hospitalization costs. This paper aims at covering this information gap, updating and integrating the existing evidence, with a cost analysis in the perspective of the Italian National Health Service (SSN).
Methods: Data were retrieved from the Roche CUP Database, the peer-reviewed literature (e.g. published cost-effectiveness studies, if any), the gray literature (e.g. regional documents for the alternative treatment cost) and unpublished data (e.g. cost-effectiveness analysis provided for price and reimbursement negotiation for medicines in CUP).
Results: We retrieved data from 14 CUPs and 3,485 patients (70% affected by tumors) (Jan 2015-August 2022). The alternative treatment mean cost per patient ranged from € 11.1 k to € 18.8 k. The net economic benefit ranged from € 47 million to € 75 million (€ 13.5 k-€ 21.5 k per patient). Avoiding alternative treatments mostly contributes to the economic benefit. The long-term economic impact accounted for 20/30% of the net economic impact. The net economic benefit for cancer drugs ranged from € 12.6 million to € 40.0 million.
Conclusions: Despite research limitations, this paper provides additional evidence on the economic impact of CUP in Italy. This could represent the first step of a broader analysis of the economic impact of early access schemes for drugs.