bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biomechanics‐based study of muscle activation under different driving conditions for Chinese percentiles
Authors: Li Mingyue , Li Biao , Chen Guoying , Huading Bao , Shi Chongyue , Yu Fei 
Published: May 2024

AbstractIn this paper, we determined the adjustment levels of the human–machine layout under the preferred driving posture for individuals with different body sizes. We also comparatively analyzed the maximum activation levels of various muscles under straight‐line driving and steering conditions. To increase the accuracy of the results, AnyBody biomechanics software was used to establish a human skeletal muscle mechanics model, which we analyzed for consistency with rig test results. The results showed that people with larger body sizes preferred a driving position with the seat reclined back. Steered driving was associated with a significant (p < .05) increase in the maximum activation of the wrist extensors, serratus anterior, deltoid, and triceps brachii, which are the main force‐generating muscle groups for steered driving, compared with straight driving. Moreover, the measured and simulated results of maximum muscle activation were relatively consistent, with the error between them within a 15% margin. In summary, this study explored the relationship between different driving conditions and preferred driving postures from a biomechanical perspective. A combined experimental and simulation approach was adopted to ensure the reliability of the findings. The insights from this study can inform ergonomic considerations for the comfort and health of Chinese drivers with varying physical characteristics.
Examination of clinical variables affecting resurgence: A reanalysis of 46 applications
Authors: Laureano Brianna , Ringdahl Joel , Falligant John M. 
Published: May 2024

AbstractDespite the efficacy of behavioral interventions, resurgence of challenging behavior (e.g., aggression, self‐injury) following successful treatment can still occur. Applied work has focused on identifying treatment‐related variables thought to affect the occurrence and magnitude of resurgence. The current study describes the relation between several variables (i.e., phase duration, response rates in baseline and treatment, obtained rates of reinforcement, downshift in reinforcement step size) and resurgence in a retrospective consecutive controlled case series of 46 treatment applications for challenging behavior conducted in an inpatient setting. Only the downshift in reinforcement (e.g., schedule‐thinning) step size was correlated with the magnitude of resurgence. These results are consistent with recent findings suggesting that treatment duration and other factors have inconsistent effects on resurgence of challenging behavior.
Child–parent agreement on the SDQ: The role of child–parent attachment and parental feelings
Authors: Hen Meirav , Shenaar‐Golan Vered , Atia Stav , Yatzkar Uri 
Published: May 2024

AbstractObjectivesChildren and their parents often provide divergent reports regarding their mental health on the Strengths and Difficulties Questionnaire (SDQ). These discrepancies may impede the diagnostic processes. The present study aimed to explore how a child's attachment to the parent and parental feelings may explain some of the variability between parent's and children's reports on the SDQ.MethodsData were collected using self‐report questionnaires from 277 children and their parents (n = 421) who were referred to a public mental health clinic. This information was classified into clinical categories (normal and abnormal) and analyzed using multinomial logistic regression.ResultsThe agreement rates between children and parents on the normality of children were high in general and across gender and age. Insecure attachment to parents positively and significantly predicted the agreement of child and parent reporting abnormality and disagreement when parents reported normality and children reported abnormality. Parental anger positively and significantly predicted disagreement in reports in which parents reported abnormal anger and children reported normal anger.ConclusionsThese findings highlight the importance of assessing informant variability in association with emotional and relationship variables as clinically meaningful information for a clinical diagnosis.
Macroscopic, microscopic, and immunofluorescent characterization of the Greek tortoise (Testudo graeca graeca) oropharyngeal floor with concern to its feed adaptation as a herbivorous land reptile
Authors: Alsafy Mohamed A. M. , El‐sharnobey Nermin K. A. , El‐Gendy Samir A. A. , Abumandour Mohamed A. , Ez Elarab Samar M. , Rashwan Ahmed M. , Hanafy Basma G. 
Published: May 2024

AbstractThe current investigation focuses on gross anatomy, light, and scanning electron microscopy (SEM) of the Testudo graeca oropharyngeal floor, with particular reference to the immunofluorescence technique to examine its tongue. The T. graeca oropharyngeal floor showed many anatomical structures: the lower rhamphotheca, paralingual ridge, lower alveolar ridge, tongue, laryngeal mound, and glottis. The lower rhamphotheca appeared as a V‐shaped jaw line with a highly serrated edge and a median tomium (beak). SEM observations of the lingual apex and the lingual body showed rectangular and conical filiform papillae with porous surfaces and taste pores. Meanwhile, the lingual root had two wings that carried papillae with different shapes: dagger‐shaped, conical, bifurcated, and leaf‐like papillae, and these papillae lacked taste pores. The laryngeal mound had openings for the laryngeal mucus gland and its secretions. Light microscopy findings showed mucous glands in the propria submucosa and near the mucosal surface of the lingual apex. The lingual root had lingual papillae and two hyaline cartilaginous skeletons between skeletal muscles, and the lingual papillae were elongated filiform, rectangular filiform papillae, and fungiform papillae. The lamina propria constituted the core of the lingual papillae and the mucous gland, they had a positive reaction with the periodic acid schiff (PAS) reagent. The apical surface of the fungiform papillae had taste pores. Under immunofluorescence, the vimentin was detected in taste bud cells, and synaptophysin reacted to the taste buds and nerve bundles. The current study of the Greek tortoise oropharyngeal floor investigated its herbivorous eating habits using its serrated lower rhamphotheca, a large tongue with differently shaped papillae, and numerous mucous glands.Research Highlights
The Greek tortoise (T. graeca graeca) oropharyngeal floor showed many anatomical structures: lower rhamphotheca, paralingual ridge, lower alveolar ridge, tongue, laryngeal mound, and glottis.
SEM and light microscopy observations of the tongue revealed varied types and shapes of lingual papillae with a porous surface on the tongue apex (rectangular or conical filiform papillae), on the tongue body (filiform and fungiform papillae), and on the tongue root (dagger‐shaped, conical, bifurcated, and leaf‐like papillae).
Light microscopy findings: the lamina propria constituted the core of the lingual papillae and had numerous mucous glands that had a slightly magenta‐red color with PAS reagent.
The apical surface of the fungiform papillae had taste pores. Vimentin and synaptophysin gave a reaction to the taste buds.
Clinical differences between drug‐induced type 1 Brugada pattern and syndrome
Authors: Sabbag Avi , Amoroso Gisella , Tomer Orr , Conte Giulio , Beinart Roy , Nof Eyal , Özkartal Tardu , Ollitrault Pierre , Laredo Mikael , Tovia‐Brodie Oholi , Gandjbakhch Estelle , de Benedictis Michele , ter Bekke Rachel M. A. , Milman Anat 
Published: May 2024

AbstractBackgroundDiagnosis of Brugada syndrome (BrS) may be established by exposing a Type 1 Brugada pattern using a sodium channel blocker. Data on the outcomes of different patient populations with drug‐induced Type 1 Brugada pattern are limited. The present study reports on the characteristics and outcome of subjects with ajmaline induced Type 1 Brugada pattern.MethodsA multicenter retrospective study including all consecutive cases of ajmaline‐induced Type 1 Brugada pattern from seven centers.ResultsA total of 260 patients (69.9% males, mean age 43.4 ± 13.5) were included. Additional characteristics included history of syncope (n = 56, 21.5%), family history of BrS (n = 58, 22.3%) or sudden cardiac death (n = 47, 18.1%) and ventricular fibrillation (n = 3, 1.2%). Patients were divided into those meeting current diagnostic criteria for drug‐induced BrS (DIBrS) and compared to the drug‐induced Brugada pattern (DIBrECG). Females were significantly overrepresented in the DIBrS group (n = 50, 40% vs. n = 29, 21.5%, p = .001). A significantly higher prevalence of type 2/3 Brugada ECG at baseline was found in the DIBrECG group (n = 108, 80.8% vs. n = 75, 60% in the DIBrS, p = .026). During a median follow up of three (IQR 1.50–5.32) years, a single event of significant arrhythmia occurred in the DIBrS group.ConclusionLess than half of subjects with ajmaline‐induced Brugada pattern met current criteria for BrS. These individuals had very low rate of adverse outcomes during a follow up of 3 years, irrespective of the indication for the test or eligibility for the BrS diagnosis.
Suppression of TNF‐α activity by immobilization rescues Mkx expression and attenuates tendon ossification in a mouse Achilles tenotomy model
Authors: Isaji Masashi , Horiuchi Keisuke , Kondo Shinya , Nakagawa Takahiro , Ishizaka Takahiro , Amako Masatoshi , Chiba Kazuhiro 
Published: May 2024

AbstractTraumatic heterotopic ossification is a condition in which extraskeletal bone formation occurs in soft tissues after injury. It most commonly occurs in patients who had major orthopedic surgery and in those with severe extremity injuries. The lesion causes local pain and can impair motor function of the affected limb, but there is currently no established prophylaxis or treatment for this condition. In this study, we show that immobilization at an early stage of the inflammatory response after injury can attenuate ossification formation in a murine Achilles tenotomy model. Gene expression analysis revealed a decrease in the expression of Tnf and an increase in the expression of Mkx, which encodes one of the master regulators of tendon differentiation, Mohawk. Notably, we found that TNF‐α suppressed the expression of Mkx transcripts and accelerated the osteogenic differentiation of tendon‐derived mesenchymal stem cells (MSCs), suggesting that TNF‐α acts as a negative regulator of Mkx transcription. Consistent with these findings, pharmaceutical inhibition of TNF‐α increased the expression of Mkx transcripts and suppressed bone formation in this mouse model. These findings reveal the previously unrecognized involvement of TNF‐α in regulating tendon MSC fate through suppression of Mkx expression and suggest that TNF‐α is a potential target for preventing traumatic heterotopic ossification.
Blind versus endoscopy‐guided postpyloric feeding tube placement in adults with ischemic stroke: A retrospective cohort study
Authors: Sun Chun , Yuan Kangyi , Gao Qiyuan , Liu Fang , Long Yuanxi , Wang Li 
Published: May 2024

AbstractBackgroundThis study compared the one‐time success rate of blind and endoscopy‐guided postpyloric feeding tube placement after implementing a comprehensive nursing scheme of intestinal blind placement for patients with ischemic stroke.MethodsThis retrospective cohort study included 179 patients with blind bedside placement and 118 with endoscopy‐guided placement. The primary outcome was the one‐time success rate of radiologically confirmed postpyloric placement. The secondary endpoints included the position of the tube tip, length of insertion, time of placement, and expenses. The safety endpoints were the incidence of complications caused by placement.ResultsThe results showed that the method of tube placement did not significantly affect the outcome of the first tube placement (odds ratio [OR] = 0.41; 95% CI = 0.137–1.207; P = 0.105). Compared with endoscopy‐guided placement, blind placement was half the cost. We also found that a history of abdominal surgery (OR = 0.003; 95% CI  = 0.000–0.059; P < 0.001) and longer intensive care unit (ICU) days (OR = 0.94; 95% CI = 0.903–0.981; P = 0.004) were inversely associated with the one‐time success rate.ConclusionOur study suggested that blind intestinal feeding tube placement has an equivalent one‐time success rate compared with endoscopy‐guided placement in hospitalized patients with ischemic stroke if operators can be trained well. However, the expenses of endoscopy‐guided placement were twice those of blind bedside methods. We also found that patients with abdominal surgery history and longer ICU stay were more likely to fail at the first placement. Further research is needed to replicate our single‐center observations in a larger population of patients.
Detection of cystic and alveolar echinococcosis based on tissue surface‐enhanced Raman spectroscopy combined with deep learning
Authors: Du Yu , Zheng Xiangxiang , Lv Guodong , Yin Longfei , Wu Guohua , You Zhaonan 
Published: May 2024

AbstractEchinococcosis chiefly includes cystic and alveolar echinococcosis, which is a parasitic disease. It is very important to find a quick and non‐staining method to determine whether a tissue sample has echinococcosis lesions; it is not only conducive to the diagnosis of echinococcosis but also conducive to the judgment after surgery. In the study, tissue surface‐enhanced Raman spectroscopy (SERS) in combination with deep learning was used to classify cystic and alveolar echinococcosis and healthy controls. Silver nanoparticles served as SERS‐enhanced substrates, and a large amount of tissue SERS spectra was collected. There were 24 cases of cystic echinococcosis tissue, 14 cases of alveolar echinococcosis tissue, and 21 cases of healthy control tissues, and the numbers of SERS spectra collected were 594, 410, and 990, respectively, for a total of 1994 spectra. The convolutional neural network (CNN) was used to categorize SERS spectra into three types. Four other common machine learning classification algorithms were compared with the CNN model to highlight the classification effect of the CNN model. The results show that the model with the best effect is the CNN model, whose accuracy reaches 95%. Therefore, SERS combined with the CNN model has great potential for distinguishing the tissues of cystic and alveolar echinococcosis.
Modulation on structure and electric properties by tantalum of lead‐free NaNbO3 ceramics
Authors: Wang Liguang , Huang Xiaoxia , Zhu Changming , Su Xiaofei , Yu Guibo , Zeng Pinyi , Jiang Changhao , Wang Yishuang 
Published: May 2024

AbstractThe variation of structural and electric properties is investigated via different characterization methods for NaNbO3 ceramics modified with Ta5+ ions. At room temperature, substitution of Ta5+ ions can effectively induce the phase coexistence and transition between orthorhombic antiferroelectric P and orthorhombic ferroelectric Q phase in NaNb1‐xTaxO3 ceramics. Thus, the ferroelectric and piezoelectric properties could be regulated with the maximum value of d33 (~37.3) at x = 0.05. Besides, with increasing temperature, multiple phase transitions are demonstrated through dielectric, XRD, and in situ Raman results. Moreover, the temperature of various phase transitions gradually shifts toward lower temperature with increasing Ta5+ ions. Correspondingly, the modulation mechanism is also discussed based on the evolution of Raman vibration. This work is instructive for regulatable applications of NaNbO3‐based materials.
Strategies for social venture growth: Governing the means‐ends dynamics of social impact
Authors: Roche Olivier P. , Siebold Nicole 
Published: May 2024

AbstractGoverning the growth strategies of social ventures is one of the most significant challenges social entrepreneurs face. While social entrepreneurs strive for growth mainly to increase the social venture's impact on its key stakeholders, pursuing growth may result in mission drift with a detrimental neglect of dual mission objectives and stakeholder needs. In this conceptual article, we aim to contribute to an enhanced understanding of how growth unfolds in social ventures and how the governance of growth can prevent divergence from the venture's raison d'être in tackling stakeholder needs. Building upon the literature on organizational and social impact growth, we theorize four distinct growth strategies: benevolence‐driven, collaboration‐driven, skills‐driven, and consumption‐driven social venture growth. For each strategy, we identify underlying growth dynamics and derive principles for the governance of social venture growth. This way, we add to the emergent literature on social venture growth and dual mission management.
Interfacial properties and foam performance of alpha olefin sulfonate and CO2 switchable aminopropyl methyl siloxane surfactant mixtures
Authors: Zhao Yujie , Qiu Jun , Zhu Xuedong , He Xiujuan , Li Yingcheng 
Published: May 2024

AbstractCO2‐in‐water (C/W) foams have attracted much attention given their eco‐friendliness in recent years. However, limited surfactants were able to effectively adsorb at the supercritical CO2–water (C–W) interface considering the weak solvent strength of CO2, especially at high temperatures. Herein, attempts have been made to design suitable CO2 foaming agents by evaluating the influence of proportions of anionic and cationic surfactants and the affinity between aminopropyl methyl siloxane (APSi) and CO2. Through systematical foamability and foam stability experiments, together with the measurements of C–W equilibrium and dynamic interfacial tensions, the adsorption and stabilization mechanisms of sodium alpha olefin sulfonate (AOS)‐APSi aqueous dispersions on the CO2 foam films are revealed. Excellent foam properties were observed at AOS/APSi mass ratio of 9:1, in which initial foam height (h0) and half‐life period (t1/2) first increased and then decreased with increasing pressure, whereas the interfacial tension decreased with increasing pressure. The results indicate that the interaction of anionic and cationic head‐groups contributes to accelerating the surfactant adsorption rate from bulk to the C–W interface, enhancing foamability and stabilizing foam. Besides, the AOS/APSi mass ratio of 8:2 shows a good affinity for CO2 at 15 MPa, of which h0 is 26% higher and t1/2 is 60% slower than AOS alone. Furthermore, the initial mean bubble area of both 9:1 and 8:2 AOS/APSi mixtures was around half that of AOS alone. This work broadens the design of novel surfactant methodologies including CO2 foam, providing a theoretical guidance for the application of CO2 on enhanced‐oil‐recovery technologies.
Lipids and Statin Medication With Sensorineural Hearing Loss: A Mendelian Randomization Study
Authors: Wu Haoyang , Deng Wenting , Luo Yuelian , Xu Yaodong , Xiong Hao 
Published: May 2024

BackgroundRecent insights suggest that lipids and statin medication play a role in the development of sensorineural hearing loss (SNHL), yet the exact role remains controversial. This research applied Mendelian randomization (MR) to assess whether lipids and statin medication are associated with an increased risk of SNHL.MethodsA two‐sample MR was used in this study. Genetic instruments were constructed from variants associated with risk factors. Data for lipids and statin medication were obtained from the IEU OpenGWAS project, and for SNHL from the Finngen research project, which comprises 32,487 individuals with SNHL and 331,736 control individuals.ResultsGenetically predicted higher levels of triglycerides were associated with an increased risk of SNHL. The use of genetically predicted atorvastatin was associated with a lower risk of SNHL. Rosuvastatin has demonstrated potential in treating SNHL, yet further investigations are warranted to elucidate its relationship with SNHL. Insufficient evidence was available to suggest that the genetically predicted level of high‐density lipoprotein cholesterol or low‐density lipoprotein cholesterol or the use of simvastatin were associated with SNHL.ConclusionsThe study provides genetic evidence suggesting that increased levels of triglycerides in the blood could be a risk factor for SNHL and that the use of certain statin medications, including atorvastatin and rosuvastatin, could reduce the risk of SNHL. These results align with findings from previous observational studies that have linked hyperlipidemia with the risk of SNHL.Level of EvidenceAccording to the Oxford Centre for Evidence‐Based Medicine 2011 levels of Evidence, the study has a third level of Evidence Laryngoscope, 134:4366–4373, 2024
Airway and Voice Outcomes After Thyroarytenoid Myomectomy for Bilateral Vocal Fold Immobility
Authors: Yang Zao M. , Malka Ronit , Erwin Dylan Z. , Postma Gregory 
Published: May 2024

IntroductionType 4 posterior glottic stenosis and bilateral vocal fold paralysis are clinically challenging causes of bilateral vocal fold immobility (BVFI) that result in glottic airway obstruction. Established procedures for BVFI typically worsen dysphonia. We hypothesize the use of thyroarytenoid myomectomy (TAM) in the setting of BVFI will improve dyspnea with decreased detriment to voice.MethodsEleven unilateral TAM procedures were performed between April 2021 and June 2023 at a single institution. Pre‐ and postoperative patient reported outcomes were compared. Representative images of maximal glottic opening were analyzed in ImageJ to calculate ipsilateral bowing index (BI), total BI, maximum glottic surface area (MGSA), and maximum opening angle (MOA). Statistical comparisons were performed with paired t‐tests when normality was confirmed with Shapiro–Wilk test and otherwise with Wilcoxon signed‐rank tests, with threshold for significance of α = 0.05. Interrater reliability for objective glottal measures was compared with intraclass correlation coefficient (ICC).ResultsDyspnea Index improved from mean (standard error) of 24.1 (3.8) to 9.1 (3.3), p = 0.004. Voice Handicap Index‐10 improved from 20.0 (4) to 10.3 (3.8), p = 0.011. Glottal Function Index improved from 9.6 (1.4) to 6.3 (1.3), p = 0.017. There was no significant difference in ipsilateral BI, total BI, MOA, and median MGSA. There was good to excellent ICCs for all comparisons (0.83–0.95).ConclusionsTAM demonstrated significant improvement in symptoms from BVFI while not significantly altering glottal structure. These data suggest TAM improves dyspnea in patients with BVFI without significantly impairing voice.Level of Evidence4 Laryngoscope, 134:4307–4312, 2024
Crop pest identification using deep network based extracted features and MobileENet in smart agriculture
Authors: K S Guruprakash , P Siva Karthik , A Ramachandran , K Gayathri 
Published: May 2024

AbstractAgriculture has been considered an important source of food for humans throughout history. Plant pests cause significant damage to crops and reduce the productivity of global crop yields. Therefore, it is important to identify the plant pest at an earlier stage in order to minimize crop losses and use pesticides optimally. This paper develops the MobileENet deep learning architecture for accurate plant pest identification with less computational effort. The input images are pre‐processed, and the features are extracted using a deep convolutional encoder–decoder network (DCEDN). The proposed classification approach solves the problems of over‐fitting regularization, batch normalization, and dropout layers. Due to the minimum computing size and factorization process, the classification performance is increased. It extracts discriminatory feature information by eliminating redundant background information. The performance of the proposed approach is evaluated on the IP102 dataset, and the performance is compared with existing deep learning‐based approaches. The performance metrics, such as accuracy, precision, recall, and so forth, are considered to evaluate the performance of the proposed plant pest identification approach. The accuracy performance of the proposed approach is improved to 98.83% with less information loss.