bluuebunny/crossref_metadata_2025_split huggingface dataset:
Remaking the Connections
Authors: Neilson David 
Published: October 2011

The current Robert Boyer-led French Regulation School (FRS) characterizes the contemporary era as a diversity of national capitalisms. Boyer’s new approach displaces the original FRS focus on “models of development.” This article rallies against the current direction and re-engages the FRS’s earlier mid-range Marxist-influenced account of capitalist development. In particular, key concepts of “regulation” and “model of development” are reworked in the context of a revised account of the Fordist model of development. These concepts are then adapted to work up an outline of the “neoliberal model of development.” JEL classification: B50, F59, O57
Bone Status in Activity-Restricted Pregnant Women Assessed Using Calcaneal Quantitative Ultrasound
Authors: Brandao Kristen L. , Mottola Michelle F. , Gratton Robert , Maloni Judith 
Published: October 2011

Objective: Pregnancy-induced bone loss may be further exacerbated by activity restriction (AR). The authors compared the bone status of AR hospitalized (≥7 days) pregnant women in the third trimester to ambulatory (AM) women at the same gestational age, using a prospective cross-sectional design. Method: AR was quantified in AR women by daily step counts using a pedometer for 7 consecutive days. Bone status was evaluated in the left and right calcaneus bones of both AR ( n = 13) and AM ( n = 20) women using quantitative ultrasound (QUS). Results: AR women took an average of 1,504 ± 1,377 steps/day. Speed of sound scores (1,543.05 ± 41.97 m/s vs. 1,569.60 ± 46.12 m/s) and broadband ultrasound attenuation (BUA) scores (107.93 ± 9.59 dB/MHz vs. 114.69 ± 17.06 dB/MHz) were not different between the AR and AM groups, respectively ( p > .05). However, bone stiffness index (SI) scores (84.0 ± 16.2 vs. 95.8 ± 22.1, respectively, p < .05) were different between groups, indicating a greater relative risk of future fracture in the AR women. Conclusion: Increased fracture risk appears to be a negative side effect incurred through an average of 16 days of hospitalized AR in late pregnancy. Further investigations using a larger sample size are necessary to evaluate the effect of antepartum AR on bone status in the postpartum period to determine if bone status is further attenuated by breastfeeding or if recovery occurs with resumption of ambulation and return of menses and to assess future risk in these women as they age. Prenatal care providers should be made aware of these risks.
Personal and family history of immune-related conditions increase the risk of plasma cell disorders: a population-based study
Authors: Lindqvist Ebba K. , Goldin Lynn R. , Landgren Ola , Blimark Cecilie , Mellqvist Ulf-Henrik , Turesson Ingemar , Wahlin Anders , Björkholm Magnus , Kristinsson Sigurdur Y. 
Published: October 2011

AbstractThe associations between immune-related conditions and multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) have previously been investigated with inconsistent results. In a large population-based study, we identified 19 112 patients with MM, 5403 patients with MGUS, 96 617 matched control subjects, and 262 931 first-degree relatives. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) for the association of MM and MGUS with immune-related conditions by use of logistic regression. A personal history of all infections combined was associated with a significantly increased risk of MM (OR = 1.2; 95% CI, 1.1-1.3), and a personal history of all conditions in the categories infections (OR = 1.6; 95% CI, 1.5-1.7), inflammatory conditions (OR = 1.4; 95% CI, 1.2-1.5), and autoimmune diseases (OR = 2.1; 95% CI, 1.9-2.4) was associated with a significantly increased risk of MGUS. Several specific immune-related conditions elevated the risk of MM and/or MGUS. A family history of autoimmune disease was associated with a significantly increased risk of MGUS (OR = 1.1; 95% CI, 1.00-1.2), but not MM. Our findings suggest that immune-related conditions and/or their treatment are of importance in the etiology of MGUS and possibly MM. The association of both personal and family history of autoimmune disease with MGUS indicates the potential for shared susceptibility for these conditions.
Distance-based features in pattern classification
Authors: Tsai Chih-Fong , Lin Wei-Yang , Hong Zhen-Fu , Hsieh Chung-Yang 
Published: October 2011

Abstract
In data mining and pattern classification, feature extraction and representation methods are a very important step since the extracted features have a direct and significant impact on the classification accuracy. In literature, numbers of novel feature extraction and representation methods have been proposed. However, many of them only focus on specific domain problems. In this article, we introduce a novel distance-based feature extraction method for various pattern classification problems. Specifically, two distances are extracted, which are based on (1) the distance between the data and its intra-cluster center and (2) the distance between the data and its extra-cluster centers. Experiments based on ten datasets containing different numbers of classes, samples, and dimensions are examined. The experimental results using naïve Bayes, k-NN, and SVM classifiers show that concatenating the original features provided by the datasets to the distance-based features can improve classification accuracy except image-related datasets. In particular, the distance-based features are suitable for the datasets which have smaller numbers of classes, numbers of samples, and the lower dimensionality of features. Moreover, two datasets, which have similar characteristics, are further used to validate this finding. The result is consistent with the first experiment result that adding the distance-based features can improve the classification performance.
On the phonetic status of syllabic consonants: Evidence from Slovak
Authors: Pouplier Marianne , Beňuš Štefan 
Published: October 2011

AbstractThis paper investigates the phonetic correlates of syllable structure, focusing on syllabic consonants. Cross-linguistically, syllables containing consonantal nuclei are often subject to a number of restrictions compared to their vocalic counterparts. However, some languages, like Slovak, allow relatively freely distributed syllabic liquids. Phonetic studies of syllable structure have shown that the vowel provides the basis for the articulatory coordination relationships within a syllable, and consonant–vowel timing patterns have been identified as a primary phonetic correlate of syllable structure. However, how coordination relationships within a syllable are organized when a consonant occupies the nucleus is largely unknown. We investigate whether in Slovak, syllabic consonants change their consonantal kinematics to approach a more vowel-like articulation and whether vowel-less syllables differ in their articulatory timing characteristics from canonical syllables containing vowels. Our results show that a consonant does not change to be more like a vowel in its articulatory dynamics when occupying the nucleus position. However, we find consistent effects in articulatory timing in that consonantal syllables show less overlap on a variety of measures compared to vocalic syllables. We argue that the typological possibility for syllabic consonants may be related to the general consonant timing pattern of a language.
Realization of voiceless stops and vowels in conversational French and Spanish
Authors: Torreira Francisco , Ernestus Mirjam 
Published: October 2011

AbstractThe present study compares the realization of intervocalic voiceless stops and vowels surrounded by voiceless stops in conversational Spanish and French. Our data reveal significant differences in how these segments are realized in each language. Spanish voiceless stops tend to have shorter stop closures, display incomplete closures more often, and exhibit more voicing than French voiceless stops. As for vowels, more cases of complete devoicing and greater degrees of partial devoicing were found in French than in Spanish. Moreover, all French vowel types exhibit significantly lower F1 values than their Spanish counterparts. These findings indicate that the extent of reduction that a segment type can undergo in conversational speech can vary significantly across languages. Language differences in coarticulatory strategies and “base-of-articulation” are discussed as possible causes of our observations.
Inclined Tensile Load Testing on Short Drilled Shafts
Authors: Puppala Anand J. , Wejrungsikul Thornchaya , Williammee Richard S. , Thomas Witherspoon W. , Lozano Nicasio 
Published: October 2011

Abstract
Several drilled shafts supporting three-cable median barrier systems failed in North Texas during severe winter storms in 2006-2007. The original design of these foundations did not consider both uplift and lateral forces acting on the shafts at the same time. Since the barrier cables were fastened to the drilled shafts at an angle, it is hypothesized that an inclined pullout from both cable contraction due to seasonal temperature changes and soil softening may have contributed to the foundation failures. Hence, an attempt is made to design, conduct, and study inclined load tests on various drilled shafts of different dimensions. A total of twelve load tests were conducted on different drilled shafts in both summer and winter. This paper presents a summary of inclined load resistances of drilled shafts and vertical and horizontal movements from various types of instrumentation including the MEMS based system. The test results are also analyzed to explain the seasonal effects on the resistances of drilled shaft foundations.
Comparison of Damage Criteria for Structures to Near-Field Blast-Induced Ground Motions
Authors: Mehmet Özcan D. , Bayraktar Alemdar , Can Altunişik Ahmet 
Published: October 2011

Abstract
Our research aims to compare the existing damage standard for structures subjected to near-field blast-induced ground motions. Sixty-four different blasting records were collected from the selected quarry during 20 months in Trabzon, Turkey. Blasting characteristics such as peak particle velocities, dominant frequencies, air pressures, maximum accelerations, and maximum displacements were measured during the blasting on hard soil. Longitudinal, transverse and vertical peak particle velocities were evaluated using existing vibration standards or damage criteria such as United States (USBM 8507), Germany (DIN 4150), Sweden (SS 25210), India (IS 6922), England (BS 7385), Australia (CA 23), and Turkey. According to the U.S., English and Turkish vibration standards, the measured blast-induced ground motions did not cause the significant damage on the structures as compared with the other standards. It was observed that U.S., English, and Turkish standards are very suitable to evaluate the structural damage level of structures to near-field blast-induced ground motions. In addition, nonlinear dynamic analyses of reinforced concrete (RC) highway bridge were performed. The analytical model was constituted by ANSYS. From the analysis, displacements are increased along to the middle of the bridge deck. The maximum and minimum principal stresses are obtained at the top of the bridge column and at the middle of the bridge spans.
Education's outside
Authors: Standish Paul , Ricken Norbert 
Published: October 2011

Is the university to be thought of as in service of society — that is, on the inside? Or should it be regarded rather as its potential critic and prophet of its best prospects, and hence be understood to be on the outside? This is just one example of the multiple ways in which thinking in terms of the inside and the outside figures in educational policy and practice. While the opposition recurs across the broad range of our political and personal lives, it is there in the detail of conceptions of teaching and learning, and of the content of the curriculum. This article seeks to examine some implications of this opposition. It does this by reference to an article by Jacques Derrida in which questions concerning the inside and the outside, of inclusion and exclusion, of purity and contamination, are considered in relation to language itself and to the problems and possibilities of translation. On the surface the reflections of Paul Standish are a very good and impressive example of a European and international philosophy of education today and illustrate the overcoming of traditional limitations of language: here is an English philosopher of education dealing with a German debate between Gershom Scholem and Franz Rosenzweig in the 1920s, which was reread by a French philosopher — Jacques Derrida — in English. But from a second perspective, the reflections of Paul Standish are somehow discouraging, because one of the main topics of this article is the problem and limitation of language, the possibility and impossibility of translation and — therefore — the limitations of language in general. Therefore in this reply the author's comment will oscillate between the problems of understanding and translating — and will lead into foreignness as a consequence of these differences. In order to do this the author gives a very short reconstruction of the main ideas in order to prove that he has understood the argumentation in an adequate way (I), and then develops his questions concerning the ideas of Paul Standish (II).
Effect of Rosiglitazone on Bone Quality in a Rat Model of Insulin Resistance and Osteoporosis
Authors: Sardone Laura D. , Renlund Richard , Willett Thomas L. , Fantus Ivan G. , Grynpas Marc D. 
Published: October 2011

OBJECTIVE
Rosiglitazone (RSG) is an insulin-sensitizing drug used to treat type 2 diabetes mellitus. The A Diabetes Outcome Progression Trial (ADOPT) shows that women taking RSG experienced more fractures than patients taking other type 2 diabetes drugs. These were not osteoporotic vertebral fractures but, rather, occurred in the limbs. The purpose of this study was to investigate how RSG treatment alters bone quality, which leads to fracture risk, using the Zucker fatty rat as a model.

RESEARCH DESIGN AND METHODS
A total of 61 female 4-month-old rats were divided into six groups. One Sham group was a control and another was administered oral RSG 10 mg/kg/day. Four ovariectomized (OVX) groups were dosed as follows: controls, RSG 10 mg/kg, alendronate (ALN, injected at 0.7 mg/kg/week), and RSG 10 mg/kg plus ALN. After 12 weeks of treatment, bone quality was evaluated by mechanical testing. Microarchitecture, bone mineral density (BMD), cortical bone porosity, and bone remodeling were also measured.

RESULTS
OVX RSG 10 mg/kg rats had lower vertebral BMD and compromised trabecular architecture versus OVX controls. Increased cortical bone porosity and decreased mechanical properties occurred in these rats. ALN treatment prevented decreased BMD and architectural and mechanical properties in the OVX model. Reduced bone formation, increased marrow adiposity, and excess bone resorption were observed in RSG-treated rats.

CONCLUSIONS
RSG decreases bone quality. An unusual finding was an increase in cortical bone porosity induced by RSG, consistent with its effect on long bones of women. ALN, an inhibitor of bone resorption, enhanced mechanical strength and may provide an approach to partially counter the deleterious skeletal effects of RSG.
Single Insulin-Specific CD8+ T Cells Show Characteristic Gene Expression Profiles in Human Type 1 Diabetes
Authors: Luce Sandrine , Lemonnier François , Briand Jean-Paul , Coste Joel , Lahlou Najiba , Muller Sylviane , Larger Etienne , Rocha Benedita , Mallone Roberto , Boitard Christian 
Published: October 2011

OBJECTIVEBoth the early steps and the high recurrence of autoimmunity once the disease is established are unexplained in human type 1 diabetes. Because CD8+ T cells are central and insulin is a key autoantigen in the disease process, our objective was to characterize HLA class I–restricted autoreactive CD8+ T cells specific for preproinsulin (PPI) in recent-onset and long-standing type 1 diabetic patients and healthy control subjects.RESEARCH DESIGN AND METHODSWe used HLA-A*02:01 tetramers complexed to PPI peptides to enumerate circulating PPI-specific CD8+ T cells in patients and characterize them using membrane markers and single-cell PCR.RESULTSMost autoreactive CD8+ T cells detected in recent-onset type 1 diabetic patients are specific for leader sequence peptides, notably PPI6–14, whereas CD8+ T cells in long-standing patients recognize the B-chain peptide PPI33–42 (B9–18). Both CD8+ T-cell specificities are predominantly naïve, central, and effector memory cells, and their gene expression profile differs from cytomegalovirus-specific CD8+ T cells. PPI6–14–specific CD8+ T cells detected in one healthy control displayed Il-10 mRNA expression, which was not observed in diabetic patients.CONCLUSIONSPPI-specific CD8+ T cells in type 1 diabetic patients include central memory and target different epitopes in new-onset versus long-standing disease. Our data support the hypothesis that insulin therapy may contribute to the expansion of autoreactive CD8+ T cells in the long term.
Pharmacokinetics and Pharmacodynamics of High-Dose Human Regular U-500 Insulin Versus Human Regular U-100 Insulin in Healthy Obese Subjects
Authors: de la Peña Amparo , Riddle Matthew , Morrow Linda A. , Jiang Honghua H. , Linnebjerg Helle , Scott Adam , Win Khin M. , Hompesch Marcus , Mace Kenneth F. , Jacobson Jennie G. , Jackson Jeffrey A. 
Published: October 2011

OBJECTIVE
Human regular U-500 (U-500R) insulin (500 units/mL) is increasingly being used clinically, yet its pharmacokinetics (PK) and pharmacodynamics (PD) have not been well studied. Therefore, we compared PK and PD of clinically relevant doses of U-500R with the same doses of human regular U-100 (U-100R) insulin (100 units/mL).

RESEARCH DESIGN AND METHODS
This was a single-site, randomized, double-blind, crossover euglycemic clamp study. Single subcutaneous injections of 50- and 100-unit doses of U-500R and U-100R were administered to 24 healthy obese subjects.

RESULTS
Both overall insulin exposure (area under the serum insulin concentration versus time curve from zero to return to baseline [AUC0-t’]) and overall effect (total glucose infused during a clamp) were similar between formulations at both 50- and 100-unit doses (90% [CI] of ratios contained within [0.80, 1.25]). However, peak concentration and effect were significantly lower for U-500R at both doses (P &lt; 0.05). Both formulations produced relatively long durations of action (18.3 to 21.5 h). Time-to-peak concentration and time to maximum effect were significantly longer for U-500R than U-100R at the 100-unit dose (P &lt; 0.05). Time variables reflective of duration of action (late tRmax50, tRlast) were prolonged for U-500R versus U-100R at both doses (P &lt; 0.05).

CONCLUSIONS
Overall exposure to and action of U-500R insulin after subcutaneous injection were no different from those of U-100R insulin. For U-500R, peaks of concentration and action profiles were blunted and the effect after the peak was prolonged. These findings may help guide therapy with U-500R insulin for highly insulin-resistant patients with diabetes.
Underlying diseases in dogs referred to a veterinary teaching hospital because of dyspnea: 229 cases (2003–2007)
Authors: Fonfara Sonja , de la Heras Alegret Lourdes , German Alexander J. , Blackwood Laura , Dukes-McEwan Joanna , M. Noble P-J. , Burrow Rachel D. 
Published: October 2011

Abstract
Objective—To identify the most frequent underlying diseases in dogs examined because of dyspnea and determine whether signalment, clinical signs, and duration of clinical signs might help guide assessment of the underlying condition and prognosis.
Design—Retrospective case series.
Animals—229 dogs with dyspnea.
Procedures—Case records of dogs referred for dyspnea were reviewed and grouped according to location or etiology (upper airway, lower respiratory tract, pleural space, cardiac diseases, or obesity and stress). Signalment, clinical signs at initial examination, treatment, and survival time were analyzed.
Results—Upper airway (n = 74 [32%]) and lower respiratory tract (76 [33%]) disease were the most common diagnoses, followed by pleural space (44 [19%]) and cardiac (27 [12%]) diseases. Dogs with upper airway and pleural space disease were significantly younger than dogs with lower respiratory tract and cardiac diseases. Dogs with lower respiratory tract and associated systemic diseases were significantly less likely to be discharged from the hospital. Dogs with diseases that were treated surgically had a significantly better outcome than did medically treated patients, which were significantly more likely to be examined on an emergency basis with short duration of clinical signs.
Conclusions and Clinical Relevance—In dogs examined because of dyspnea, young dogs may be examined more frequently with breed-associated upper respiratory tract obstruction or pleural space disease after trauma, whereas older dogs may be seen more commonly with progressive lower respiratory tract or acquired cardiac diseases. Nontraumatic acute onset dyspnea is often associated with a poor prognosis, but stabilization, especially in patients with cardiac disease, is possible. Obesity can be an important contributing or exacerbating factor in dyspneic dogs.
Surficial geophysical deduction of the geomaterial and aquifer distributions at Ngor-Okpala local government area of Imo State, South Eastern Nigeria
Authors: Victor Obianwu , Innocent Chimezie , Anthony Akpan , Jimmy George 
Published: October 2011

AbstractTwenty seven vertical electrical sounding (VES) profiles surrounding four known traverses were obtained in Ngor-Okpala local government area of Imo state to examine the subsurface geomaterials and the associated groundwater potential. The VES data, constrained by borehole data, provided useful information about the subsurface hydrogeologic and lithologic conditions. From the validated interpretation, the area assessed has loamy soil, medium grained sands, well-sorted medium-grained/gravelly sands and river sand as the lithologic succession from top to the bottom of the depth penetrated. The aquifers in the area were found in the medium-grained sands and well-sorted medium-coarse-grained sands. The aquifer depth for all-season groundwater that would be devoid of draw-down can be found at a depth range of 42–50 m. The resistivity maps of selected depths exhibit sharp resistivity changes at depth due mainly to undulating subsurface topography. A map of the distribution of the kσ-values shows that good quality groundwater can be found in most parts of the area.
La psychothérapie individuelle d'orientation systémique : une thérapie sans famille ?
Authors: Duruz Nicolas 
Published: October 2011

Poursuivant en les approfondissant les réflexions d’un groupe de travail du CEF à Lausanne, consacré à la psychothérapie individuelle d’orientation systémique, l’auteur pose la question dans cet article de la légitimité pour les systémiciens d’une telle pratique : la pensée et la clinique systémiques les autorisent-elles à s’intéresser à l’individu ? L’enjeu idéologique ainsi mieux cerné, l’article peut alors aborder les questions de méthode et de techniques engagées dans un tel type de psychothérapie, et plus succinctement, celles de la formation à cette pratique.
Famille, migration et identité : à propos des bidonvilles
Authors: Rabeh Sijelmassi Aicha 
Published: October 2011

Comment dans la précarité d’un contexte socio-économique marginalisé peut-on remédier au dysfonctionnement familial ? Une association de type thérapeutique peut-elle prévenir les troubles de l’hygiène mentale dans un contexte d’exclusion ?