bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can patients with longstanding Bulimia Nervosa suffer from Severe and Enduring Eating Disorder? A qualitative study
Authors: Robinson Paul , Guidetti Giulia , Kasriel Jessica , Khawandanah Jomana , Hughes Maxine , Hachem Zeinab 
Published: April 2024

Abstract

Objectives: To interview a series of patients with bulimia nervosa of longstanding to establish their symptoms and examine the suggestion, using qualitative analysis, that the term “Severe and Enduring Bulimia Nervosa (SEED-BN)” might be appropriate and helpful.
Methods: 12 participants with Bulimia Nervosa, one male, were interviewed with the help of an interview guide. Interviews were recorded and transcribed. Transcripts were analysed using Thematic Analysis.
Results: participants with Bulimia Nervosa described serious problems in many realms, especially social, psychological, family and relationships.
Conclusions: Bulimia nervosa of long duration is associated with many serious symptoms. It seems likely that recognition of long standing bulimia nervosa as a severe and enduring eating disorder could encourage clinicians and families to pay attention to the wide variety of problems suffered by this group. Further research is required to examine this proposal. .
Validation of the English version of TOY8 Developmental Screening Tool: Examining Measurement Invariance Across Languages, Gender and Income Groups
Authors: Wo Su Woan , Alagappar Ponmalar , Yahya Amira Najiha , Woo Pei Jun 
Published: April 2024

Abstract
Background: National Health and Morbidity Survey in Malaysia (2022) revealed that there is a significant increase in developmental delay among young children. Early detection is required by using a developmental screening tool that is easy to access and cross-culturally effective. Thus, the TOY EIGHT developmental screening tool (TOY8) was developed, utilizing artificial intelligence (AI) technology and a standardized parent proxy questionnaire. The objective of this study is to examine the validity and reliability of the English TOY8 (based on existing validated Malay Toy8) and to examine measurement invariance across language versions, gender, and income groups.
Methods: TOY8 was designed and developed to screen the developmental aspects in children aged 3 to 5 years old in two languages: Malay and English, by an interdisciplinary expert panel drawing upon both national and international guidelines. Two samples of parents and their children were recruited: 1767 dyad to complete the English Toy8 and another 1724 dyad to complete the Malay Toy8.
Results: The CFA results indicate that the model structure of the English version of TOY8 matches that of the Malay version of TOY8. The split-half reliability coefficient indicated adequate to high reliability which is also consistent with the previous Malay version of TOY8. Our results showed that all configural and metric invariance model across groups showed good fit to the data demonstrating that a multiple-group CFA was appropriate. Lastly, scalar invariance was only achieved in certain domains across gender, not in the language version of income groups.
Conclusion: The English TOY8 is found to be a valid and reliable screening tool to identify developmental milestones of children aged 3-5 years old in Malaysia. In addition, configural and metric invariances across groups in all domains were established indicating the cross-cultural equivalent of the items; scalar invariance was established across genders in most of the domains of 3-5 years old. This implies that our study aligns with previous literature regarding child development, which indicates that there is a general similarity in gender and cross-cultural development domains in the first years of life but not for older children in term of language and socioemotional skills.
Double knots versus triple knots facia closure method during cesarean section; is there a difference in pain sensation or cosmetic satisfaction? A randomized controlled trial comparing two different surgical methods in terms of pain and cosmetic satisfaction
Authors: Baş Sevda , ADIGÜZEL Fikriye Işıl , HEJAZI Ghaith , NARIN Raziye 
Published: April 2024

Abstract

Background
This study aims to compare the effects of two different fascia closure techniques on cosmetic and pain outcomes after a cesarean section.
Methods
Patients planned for cesarean section were randomized into two groups. In Group I (double knots group), the edge of the fascia was identified with a Kocher clamp. A synthetic absorbable multifilament suture was used to close the fascia in a continuous fashion, starting from the opposite side up to the Kocher clamp. The knots were tied with the same single suture. In Group II (triple knots group), the edge of the fascia was fixed with the same suture material instead of the Kocher clamp. The fascia was closed similarly, starting from the opposite corner via the second loop. The loops from the first suture were tied to the second suture. Postoperative pain at and around the incision line was measured on the 1st, and 10th days postoperatively on the NRS (Numeric Rating Scale). Analgesic medication required during hospitalization was also recorded. Patient satisfaction with the final aesthetic results of the incision was assessed using a 10-point scale at the 1st and 3rd months postoperatively.
Results
A total of 711 patients were enrolled, of which 218 were randomized to each interventional group (109 patients in each of the two groups). There was no significant difference in pain scores between the groups on the 1st and the 10th postoperative days (p > 0.05). There were significant differences in nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol use between groups during the post-cesarean hospitalization. Regardless of the type of drug, patients in Group I required higher doses of pain medication than those in Group II, with median doses of NSAIDs of 3(0–5) vs. 2(0–4) and median doses of paracetamol of 4(1–7) vs. 2(0–6), respectively (p < 0.001). Group II had significantly higher aesthetic satisfaction scores than Group I in both measurements, with a median score of 9(4–10) vs. 8(2–10) at the end of the first month and 10 (5–10) vs. 9(3–10) at the end of the third month (p = 0.03,0.02, respectively).
Conclusion
Compared to double knots, fascia closure with the triple knot closure method is statistically associated with a higher aesthetic satisfaction score and less need for painkillers.
Transcriptomic and metabolomic analyses of the response of sainfoin (Onobrychis viciifolia) seedings to low-temperature stress
Authors: Cheng Jiao , Wang kun , Yao Yuheng , Wu Shiwen , Nan Lili 
Published: April 2024

Abstract

Sainfoin (Onobrychis viciifolia) is a valuable native legume forage in northwest China and is commonly used as fodder for livestock. However, low temperatures (LW) not only affect the yield and quality of sainfoin but also its geographical distribution. The leaves of the cold-tolerant new line of P4 and the cold-sensitive material of 13709 were collected after low temperature (4℃) treatment to evaluate their molecular regulatory mechanisms during low temperature via integrative analyses of their transcriptomes and metabolomes. A comprehensive analysis was conducted, including the detection of 6619 metabolites and annotation of 6939 genes using UPLC-MS/MS analysis and the IIIumina HisSeq system. The metabolomics analysis revealed 26 common differentially accumulated metabolites (DAMs) in the cold-tolerant and cold-sensitive sainfoin at different comparisons, these metabolites are mainly divided into lipids and lipid-like molecules, and phenylpropanoids and polyketides. Transcriptome analysis identified 1045, 1412, 5010, and 3119 differentially expressed genes (DEGs) in different comparisons at the same time points. By integrating the transcriptomic and metabolomic datasets, it was observed that several DAMs were closely associated with DEGs. Functional enrichment analysis of DAMs and associated DEGs highlighted their involvement in anthocyanin biosynthesis and amino acid metabolism. Six candidate genes from the above pathways were selected for controlling the adaptation to LW stress. These findings provide valuable insights into the metabolic regulation of sainfoin under LW stress and offer guidance for improving its cold resistance and selecting cold-tolerant varieties.
Dual Impacts of Urbanization and Precipitation on Subsidence in Chongqing Revealed by SBAS-InSAR
Authors: Zhang Jinlai , Tao Yuxiang , Kou Pinglang , Jin Zhao , Huang Yijian , Cui Jinhu , Liang Wenli , Liu Rui 
Published: April 2024

Abstract
Rapid urbanization in Southwest China has exacerbated ground subsidence, imposing severe threats to infrastructure and the environment. However, an understanding of the intricate multi-factorial mechanisms inducing urban subsidence remains inadequate. This study harnesses 44 Sentinel-1A images and InSAR to gauge spaciotemporal patterns of urbanized subsidence in Chongqing from 2021–2022. Results reveal subsidence up to 8 mm/yr across 26 km2, with hotspots near subway lines, construction sites, and agricultural regions. Subsidence along metro lines likely stems from excavation and vibrations during operation. The proliferation of high-rise buildings has sharply increased loading, accelerating consolidation and deformation. Agricultural land experiences substantial subsidence due to groundwater extraction. Moreover, precipitation demonstrates a negative correlation with subsidence. Heavy rainfall during spring and summer replenishes soil moisture, alleviating consolidation. Whereas reduced precipitation in fall and winter diminishes support from bedrock, aggravating subsidence. These findings underscore anthropogenic activities as primary drivers of urban subsidence. Monitoring infrastructure and minimizing land conversion is critical for mitigation. This study demonstrates InSAR's prowess in unveiling subsidence mechanisms, guiding sustainable urban development.
Tuning LLaMA Model with Mental Disorders Knowledge
Authors: Zhao Xiujie , Gao Yu , Zhang Yimeng 
Published: April 2024

Abstract

Large Language Models (LLMs) have shown its strong emergent ability in many general domain and can achieve good results in natural language processing (NLP) tasks. However, LLMs have not yet shown promising ability in the medical field, especially in the diagnosis of mental disorders, due to the protection of patients' private information and the limitation of psychological terminology. To this end, we collected nearly 7000 real medical records of various mental disorders from a specialized hospital and used them as instruction after data cleansing and manual proofreading for psychological field. We proposed the model named “ZhiXin”, a LLaMA-based model that has been fine-tuned with our own instruction. The experimental results show that our model outperforms the state-of-the-art approaches in terms of mental disorders diagnosis. In the meanwhile, our model also ensures the Safety, Usability and Smoothness of the response which is closer to the answer of a psychiatrist during the diagnosis of mental disorders. Thus ZinXin model can help patients and families with intelligent assisted diagnosis and reduce the workload of psychologists.
Preschool Teachers Attitude Towards Inclusive Education for Students With Autism Spectrum Disorders in Public Schools, Addis Ababa, Ethiopia, 2024. Multicenter Cross Sectional Study
Authors: TSEGAYE MIZAN , MENBERE FASIL , GODIE YOHANNES , BIRHANU DIRES 
Published: April 2024

Abstract
Background
Autism spectrum disorder (ASD) is a neurodevelopmental disorder primarily impacting social communication and behavior. The prevalence of ASD has been rapidly increasing, leading to a corresponding rise in the number of children with ASD attending mainstream schools. Preschool and primary school teachers have a vital role in identifying and supporting these children. However, the extent of teachers' Attitude towards including children with ASD in their classrooms remains uncertain.
Objective
The aim of this study was to evaluate the attitude towards including children with autism spectrum disorders in their classrooms, and associated factors among preschool and primary school teachers in public schools in Addis Ababa.
Methods and Materials:
Data from preschool and primary school teachers were collected using a self-administered questionnaire between September 2023 and December 2023. The collected data were analyzed utilizing SPSS version 27. Descriptive statistics were employed to summarize the findings, while bivariate binary logistic regression was utilized to examine associations between variables.
Results
The study findings revealed that only 35.5% of teachers had adequate knowledge, and the mean attitude score was 3.4, indicating a slight positive inclination towards inclusive education. Teachers between the ages of 20 and 25 had 90% lower knowledge compared to those above 40 years (AOR = 0.1, 95% CI = 0.48–0.7) with a p-value of 0.014. Furthermore, teachers with a positive attitude towards including students in regular classes were 72% more likely to have adequate knowledge (AOR = 0.28, 95% CI = 0.1–0.6) with a p-value of < 0.001. Finally, teachers whose source of knowledge about ASD did not come from surrounding people were 2.5 times more likely to have a positive attitude (AOR = 2.5, 95% CI = 1–6).
Conclusion and recommendation
The findings of this study indicate teachers displayed a generally positive attitude towards ASD. This highlights the need for increased emphasis on educational interventions aimed at enhancing attitudes towards ASD further.
Synthesis, evaluation of mechanical properties of chitosan-PVA nanofibers scaffold properties with decellularized periodontal tissue
Authors: Rzazadeh Fahimeh , Alizadeh Ali Akbar , Shirvani Fatemeh , Alavi Omid , Alipour Hamed , rezazadeh Hojat , Khorami Elham Tayebi , Tabesh Amir 
Published: April 2024

Abstract

Aims: This study was performed to fabricate and evaluate the mechanical and cellular properties of PVA-Chitosan scaffold with and without decellularized tissue for its application in tissue engineering.
Materials and Methods: In this experimental study, periodontal ligament tissue from human Wisdom Teeth were extracted. Three groups of scaffolds were fabricated by electrospining method: PVA-Chitosan scaffold, PVA-Chitosan scaffold with 0.5 % decellularized tissue and PVA-Chitosan scaffold with 1 % decellularized tissue (dECM). Then, physical evaluation (water uptake test, weight loss test, tensile test was conducted. Scanning electron microscopy (SEM) was done for evaluating surface characteristics and morphology. Moreover, in vitro biocompatibility test (MTT assay, Cell adhesion assay) and differentiation test (alkaline phosphatase activity test, Alizarin Red Staining) was done. One Way ANOVA test was used for statistical analysis.
Results: Present study was shown PVA-Chitosan scaffold with dECM had more water uptake and less tensile strength. It also showed higher levels of degradation, cellular adhesion, cellular viability and differentiation than PVA-Chitosan alone. With adding dECM, SEM images demonstrated more fiber diameter, porosity and pore size in scaffolds.
Conclusion: The present data described the characterization of a novel dECM-based PVA-Chitosan scaffold with appropriate mechanical (water uptake and degradation rate) and biological properties (cellular adhesion, cellular viability and differentiation) via decellularizing periodontal tissues in compare it with PVA-Chitosan scaffold alone.
Combination of electrochemical and Fe2+ -activated persulfate oxidation for improving the dewaterability of aerobically digested sludge
Authors: Sarkari Faranak , Gajidoust Hossein , Yan Jia 
Published: April 2024

Abstract

This study uses two methods to condition aerobically digested sludge: electrochemical-Fe2+-activated PDS (E/Fe2+/PS) and Fe2+-activated PDS (Fe2+/PS). Due to the results of current studies, a comparison has been provided between these two methods to indicate the beneficial effect of applying electrical voltage on the generation of sulfate radicals and improving the dewaterability of sludge. TTF is measured to evaluate the efficiency of these conditioning methods. The Fe2+/PS process in the optimal retention time of 17 minutes decreased TTF by 50%. The E/Fe2+/PS process reduced TTF by 64% in the optimal retention time of 13 minutes and the voltage of 5V. In both methods, the optimal Persulfate concentration was 40mg/gDS. Sludge conditioning with both processes reduced compressibility and increased filtration yield, indicating that both methods can act as a physical conditioner (skeleton builder). Also, both pretreatments decreased the bound water of sludge, suggesting that both processes can serve as chemical conditioners, too. However, the E/Fe2+/PS process performs better in sludge conditioning when the concentrations of persulfate and iron are low. This phenomenon can be attributed to the regeneration of ferrous ions (Fe2+), acting as compensatory agents for the insufficiency of Fe2+, thereby ameliorating sludge dewatering efficiency.
Clinical characteristics and detection of MYB-QKI fusions in patients with Angiocentric glioma
Authors: Li Tiemin , Hu Yue , Zhang Huawei , Aihemaitiniyazi Adilijiang , Wei Da , Guan Yuguang , Zhou Jian , Qi Xueling , Wang Mengyang , Wu Bin , Zhu Mingwang , Zhang Linpeng , Luan Guoming , Liu Changqing 
Published: April 2024

Abstract

Purpose
Angiocentric glioma (AG), a benign tumor identified within the last two decades, was officially included in the 2007 WHO Classification of Tumors of the Central Nervous System, WHO grade I. The tumor is relatively rare, with only approximately 100 cases reported. We aim to complement the characteristics and long-term prognosis of AG, as well as to detect MYB-QKI fusions.
Methods
The characteristics of all cases collected between 1 March 2009 and 1 March 2023 at the Beijing Sanbo Brain Hospital, Capital Medical University, were summarized and analyzed. Additionally, all fourteen patients were tested for MYB-QKI fusions.
Results
AG more predominantly occurs in adolescents (median age 16.5-year-old), and commonly presents with drug-resistant epilepsy. AG is frequently localized in the supratentorial regions and only one patient is in the brainstem. Brain parenchyma atrophy, and stalk-like signs can observe in imaging. Pathologically, tumor cells are perivascular pseudorosettes, presenting immunoreactivity for GFAP, S-100, Vimentin, “dot-like” staining for EMA, and low proliferative activity. Pleomorphic xanthoastrocytoma (PXA) tumor-like and tumor giant cells were observed in one patient, focal cortex dysplasia was observed in four patients. Twelve of fourteen (85.7%) patients were found with MYB-QKI fusions. Completely surgical resection typically has a satisfactory prognosis with long-term follow-up.
Conclusion
AG is a rare benign tumor with a favorable prognosis after complete resection, characterized by refractory epilepsy, frequently occurring in adolescents. MYB-QKI fusions were detected in most AG patients, as a good defining genetic alteration pathologically. The potential presence of focal cortical dysplasia (FCD) may affect the prognosis of epilepsy.
Comparative Analysis of Plant Disease Detection Models on RISC-Based Systems: AMiniTensorflow Approach
Authors: Tanksale Rushikesh , Mane Sunil B 
Published: April 2024

Abstract

Purpose: This research aims to evaluate the performance of four distinct deep learning models, namely EfficientNet B3, GoogLeNet, DenseNet, and VGG16, in the context of plant disease classification. The primary purpose is to investigate their accuracy, efficiency, and resource utilization, providing valuable insights for optimal model selection in agriculture.
Methods: The study employs a systematic approach, training each model on a diverse dataset encompassing various plant types and diseases. The training spans multiple epochs, and model evaluations are conducted using rigorous metrics such as accuracy, precision, recall, and latency. Furthermore, the resource utilization of each model is examined, considering CPU and RAM utilization, temperature, and Total Design Power (TDP).
Results: EfficientNet B3 emerges as the top-performing model, showcasing high accuracy and efficiency across various plant types. GoogLeNet and DenseNet also demonstrate competitive results, while VGG16, though satisfactory, exhibits slightly lower accuracy. In terms of resource utilization, EfficientNet B3 stands out as the most efficient, emphasizing its suitability for resource-constrained environments.
Conclusion: This research contributes valuable insights into the comparative performance of deep learning models for plant disease classification. The findings highlight EfficientNet B3 as a robust and efficient choice, particularly for applications where computational resources are limited. The study underscores the importance of considering both accuracy and resource utilization metrics for informed model selection in agricultural settings, paving the way for enhanced crop disease management strategies.
Status of scientific research integrity knowledge in dental undergraduates from 34 universities in China
Authors: WU Xiaojin , ZHENG Tongxin , NIE Yufei , WU Jingyi , CHEN Jirong , Pathak Janak L , WU Lihong 
Published: April 2024

Abstract

Background
This study aimed to investigatethe status of research integrity knowledge among dental undergraduates from 34 Chinese universities and 5 key demographic regions.
Methods
Questionnaires regarding the knowledge of scientific research integrity including, perception, attitude, and first-hand experience of scientific research integrity were distributed to dental undergraduates of 34 Chinese universities. We divided these universities into 5 key demographic reasons i.e. eastern, western, northern, southern, and central. The questionnaires filled up by 1514 participants were further analyzed.
Results
The results showed that most students acquire scientific integrity knowledge from courses and ideological or political education, and some students from other ways such as books and conferences. In terms of attitude, the vast majority of students are opposed to scientific misconduct, but a small number of students admitted that they have been involved in some sort of violation of scientific integrity by fabricating data, altering experimental results, and so on.
Conclusion Our results indicate that the academic and research environment with strict scientific integrity, implementation of scientific integrity courses in the curriculum, and proper supervision regarding scientific integrity are vital to improving the status of scientific research integrity knowledge in dental undergraduates in Chinese universities.