bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 4‐year intervention to increase adoption of safer dairy farming work practices
Authors: Chapman Larry J. , Brunette Christopher M. , Karsh Ben‐Tzion , Taveira Alvaro D. , Josefsson K. Gunnar 
Published: November 2010

AbstractBackgroundTraumatic and musculoskeletal injury rates have been high in dairy farming compared to other industries. Previous work has shown that social marketing efforts can persuade farm managers to adopt practices that reduce injury hazards compared to traditional practices if the new practices maintain profits.MethodsThe intervention disseminated information to 4,300 Northeast Wisconsin dairy farm managers about three safer and more profitable production practices (barn lights, silage bags, and calf feed mixing sites) using information channels that these managers were known to rely on. We evaluated rolling, independent, community‐based samples, at baseline and then again after each of four intervention years. We also evaluated samples from Maryland's 1,200 dairy farms after the second through the fourth year of the intervention. Maryland dairy managers read many of the same nationally distributed print mass media that we used in the intervention and so were a “partially exposed” comparison group.ResultsThe intervention to disseminate information about the innovations was successful. In comparisons before and after the intervention, Wisconsin managers reported getting more information about calf sites from public events and equipment dealers, about silage bags from other farmers and equipment dealers, and about barn lights from public events, other farmers, equipment dealers, consultants, and electrical suppliers. Wisconsin managers also reported getting more information than Maryland managers from public events for barn lights and silage bags. During years three and four, the intervention managed to sustain, but not improve, earlier increases in adoption and awareness from the first 2 years. After adjusting for farm manager and operation variables, intervention years was associated with increased Wisconsin manager adoption of two of three practices in comparisons between the baseline and the fourth intervention year: barn lights (odds ratio = 5.58, 95% confidence interval = 3.39–9.17) and silage bags (OR = 2.94, CI = 1.84–4.70). There were similar results for awareness of barn lights and the calf feeding sites. Compared to Maryland managers, Wisconsin managers reported greater awareness of barn lights.ConclusionsDisseminating information to managers through information channels that they usually consulted was associated with increased reports of getting information and with greater adoption and awareness of safer, profit‐enhancing work practices in a high hazard industry. Am. J. Ind. Med. 54:232–243, 2011. © 2010 Wiley‐Liss, Inc.
Trends in common rhinologic illnesses: Analysis of U.S. healthcare surveys 1995–2007
Authors: Mattos Jose L. , Woodard Charles R. , Payne Spencer C. 
Published: November 2010

AbstractBackgroundUp to date information on the epidemiology of, and recent changes in, allergic rhinitis (AR), acute sinusitis (AS), and chronic sinusitis (CS) office and emergency department (ED) visits and prevalence is sparse. Current studies may quote data that is outdated or based solely on patient self‐report. The purpose of this work was to describe basic epidemiologic measures of office and ED visits for AR, AS, and CS between 1995 and 2007, and to analyze trends over time for each of these diseases.MethodsSurvey data from the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) were examined from 1995 to 2007 for AR, AS, and CS by International Classification of Diseases, 9th edition (ICD‐9) code, using the STATA statistical package survey‐specific commands to obtain appropriate estimates. Subgroup analyses were performed for age, sex (male and female), race (white and black), and region. Logistic regression was used in order to investigate the predictors mentioned above in a multivariate model, and to analyze trends over time.ResultsFor AR, there has been an increase in visits in both the office and ED settings between 1995 and 2007. For CS, there has been a decrease in the proportion of both office and ED visits over this time period, as well as in the visit rate. For CS office visits, there has been an increase in the total number of visits. For AS, descriptive data show an increase in both the total number and proportion of office visits, but logistic regression did not validate these findings. There has been a decrease in ED visits for AS. Age, sex, race, and region have differing effects on each these diseases, and these factors appear to be setting‐dependent as well.ConclusionWhile regression did not show statistically significant changes for AS, the odds ratio along with the number and proportion of visits suggests that an increase for AS at a similar rate of AR is possible, lending support to a relationship between these disease processes. The relatively small increase in the prevalence of AR in the United States when compared with the worldwide increase in developing countries suggests that the hygiene theory and environmental factors play a leading role in the development of AR. The relative decrease in the prevalence of CS may be the result of successful medical therapy with the increased use of nasal steroids and nasal saline irrigation. © 2011 ARS‐AAOA, LLC.
Expression of Matrix Metalloproteinase‐9 mRNA and Vascular Endothelial Growth Factor Protein in Gastric Carcinoma and Its Relationship to Its Pathological Features and Prognosis
Authors: Yang Qiong , Ye Zai‐Yuan , Zhang Jing‐Xia , Tao Hou‐Quan , Li Shu‐Guang , Zhao Zhong‐Sheng 
Published: November 2010

AbstractTo investigate matrix metalloproteinase‐9 (MMP‐9) mRNA and vascular endothelial growth factor (VEGF) protein expression in gastric carcinoma and its correlation with microvascular density, growth‐pattern, invasion, metastasis, and prognosis. In situ hybridization of MMP‐9 mRNA and immunohistochemistry of VEGF and CD34 proteins were performed on surgical specimens of gastric cancers from 118 patients compared with 20 nonmalignant gastric mucosae. Their relationships to pathological parameters and survival times were determined by statistical analysis. The positive rate of MMP‐9 in noncancerous gastric mucosae was significantly lower than that of gastric cancer tissue (60.17%, P < 0.01). In patients with cancers of the infiltrating type, at stage T3‐T4, with vessel invasion, lymphatic metastasis, hepatic, or peritoneal metastasis, the positive expression rates of MMP‐9 mRNA, VEGF protein, and CD34 were significantly higher than those for patients with tumors of the expanding type (P < 0.01), at stage T1–T2 (P < 0.01), with nonvessel invasion (P < 0.05), without lymphatic metastasis (P < 0.05), and without hepatic (P < 0.001) or peritoneal metastasis (P < 0.001), respectively. Expression of MMP‐9 mRNA was positively related to that of VEGF protein (P < 0.001) and microvascular density (P < 0.001). Patients with higher MMP‐9 mRNA and VEGF expression demonstrated vivid tumor angiogenesis and poor 5‐year survival rate. MMP‐9 and VEGF expression is associated with enhanced tumor angiogenesis and may play crucial roles in the invasion and metastasis of gastric carcinoma. Therefore, MMP‐9 and VEGF may represent prognostic biomarkers and promising targets for therapeutic intervention. Anat Rec, 2010. © 2010 Wiley‐Liss, Inc.
Vimentin Intermediate Filaments: the Central Base in Sinus Endothelial Cells of the Rat Spleen
Authors: Uehara Kiyoko , Uehara Akira 
Published: November 2010

AbstractThe ultrastructural distribution of vimentin intermediate filaments (IFs) and localizations of the related proteins in sinus endothelial cells of the rat spleen was examined by confocal laser scanning and electron microscopy with detergent extraction, myosin‐fragment 1 decoration, and immunogold labeling to elucidate their functions in endothelial cells. Vimentin IFs were extremely abundant over stress fibers in the basal part of the endothelial cells. Some of them were intermingled with actin filaments in stress fibers, and were associated with coated vesicles. Plectin was predominantly localized in the layers of vimentin and stress fibers of the endothelial cells, but rarely in the vicinity of adherens junctions in the lateral part and focal adhesions in the basal part of the cells. Neither plakoglobin nor desmoplakin, which is coupled VE‐cadherin to vimentin IFs, was detected in sinus endothelial cells. Vinculin was localized in the basal membranes of the endothelial cells. These data suggest that abundant vimentin IFs are associated with stress fibers by plectin in the basal part of the cells and form cytoskeletal cores of sinus endothelial cells only partially supported by the ring‐shaped basal lamina to have roles in scaffolding and the mechanical stabilization of the endothelial cells. Furthermore, taken in connection with recently revealed functions of vimentin and plectin, vimentin might play a cytoskeletal core of sinus endothelial cells. Anat Rec, 2010. © 2010 Wiley‐Liss, Inc.
Antiparkinsonian Effects of Novel Adenosine A2AReceptor Antagonists
Authors: Drabczyńska Anna , Zygmunt Małgorzata , Sapa Jacek , Filipek Barbara , Müller Christa E. , Kieć‐Kononowicz Katarzyna 
Published: November 2010

AbstractThe present work describes the synthesis of a pyrazinopurinedione derivative which was together with a series of pyrimidopurinedione derivatives tested for potential antiparkinsonian activity in two tests: the “oxotremorine” and the “reserpine” test. For the studies compounds which had shown affinity for the adenosine A2Areceptor were chosen. One compound, a pyrazinopurinedione derivative, without affinity for A2Areceptors, but showing adenosine A1receptor affinity was also investigated. The performed preliminary tests indicated that, contrary to the pyrazinopurinedione all pyrimidopurinediones demonstrated antiparkinsonian effects. As a result of present studies it may be concluded that antiparkinsonian effects of the examined compounds are correlated with the antagonistic activity toward adenosine A2Areceptors in this class of compounds. However a direct correlation of the potency of both effects was not observed possibly due to different pharmacokinetic properties of the compounds. The most active derivatives of the present series were aryl‐substituted pyrimidopurinediones.
Design, Synthesis and Evaluation of Cytotoxicity of Novel Chromeno[4,3‐b]quinoline Derivatives
Authors: Miri Ramin , Motamedi Radineh , Rezaei Mohammad Reza , Firuzi Omidreza , Javidnia Azita , Shafiee Abbas 
Published: November 2010

AbstractIn the present work 15 new 1,4‐dihydropyridines (DHPs) bearing a coumarin ring were synthesized and assessed on 4 different human cancer cell lines (HeLa, K562, LS180, and MCF‐7). Although, all the derivatives were inactive on LS180 cell line, the results on other cells showed that these compounds had weak to moderate antitumoral activities and their IC50 ranged from 25 to >100 µM. Among the synthesized compounds, 7‐(2‐nitrophenyl)‐8,9,10,12‐tetrahydro‐7H‐chromeno[4,3‐b]quinoline‐6,8‐dione (6a) demonstrated the highest activity (IC50 range in different cell lines: 25.4–58.6 µM). Furthermore, the calcium channel antagonist activity of the derivatives, an undesired effect when these compounds are used as antitumoral agents, was much lower than nifedipine, a reference antagonist. In conclusion, this group of compounds seems to have promising biological properties and further investigation on this group could potentially lead to the discovery of cytotoxic agents with low calcium channel blocking activity.
Triazine‐Based Polymers as Nanostructured Supports for the Liquid‐Phase Oxidation of Alcohols
Authors: Chan‐Thaw Carine E. , Villa Alberto , Prati Laura , Thomas Arne 
Published: November 2010

AbstractA covalent triazine framework (CTF) was used as support for palladium nanoparticles (NPs) and Pd/CTF was applied as the catalyst in the selective oxidation of benzyl alcohol. N groups in the CTF appeared more efficient than those created on carbon nanotubes (CNTs) by NH3/high‐temperature treatment in stabilizing Pd NPs against growth during the immobilization step. This assured a high metal dispersion, which led to a highly active and stable catalyst in the alcohol oxidation reaction. Indeed, Pd on the CTF was more stable in recycling than Pd on activated carbon (AC) and on nitrogen‐doped CNTs, particularly avoiding leaching of Pd NPs. Moreover, Pd on the CTF was less sensitive than Pd on AC to the decrease of reactant concentration. This in turn led to a higher selectivity to benzaldehyde (98 %) with a considerable activity (turnover frequency 1453 h−1).
A Minimalist NMR Approach for the Structural Revision of Mucoxin
Authors: Yan Jun , Garzan Atefeh , Narayan Radha S. , Vasileiou Chrysoula , Borhan Babak 
Published: November 2010

AbstractIn an attempt to revise the structural assignment of mucoxin, and faced with 64 diastereomeric possibilities, we resorted to the synthesis of truncated structures that contained the core stereochemical sites. Twelve stereochemical analogues were synthesized, their 1H and 13C NMR spectra were analyzed and four recurring stereochemical trends were distilled from the data. Applying the observed trends to the diastereomeric population pared the possible choices for the correct structure of mucoxin from 64 to 4. Synthesis of these analogues led to the identification of the correct structure of mucoxin.
ChemInform Abstract: Electrical Transport Properties of F‐Doped LaFeAsO Oxypnictide.
Authors: Zhao Li‐Dong , Berardan David , Dragoe Nita 
Published: November 2010

AbstractLaFeAsO1‐xFx (x = 0, 0.075, 0.15, 0.225) is synthesized by solid state reaction of LaAs, Fe2O3, FeF2, and Fe powders (1150 °C, 50 h) and characterized by XRD, electrical resistivity, and Seebeck coefficient measurements.
ChemInform Abstract: Room Temperature Magnetic and Magnetocaloric Properties of La0.67Ba0.33Mn0.98Ti0.02 O3 Perovskite.
Authors: Oumezzine Ma. , Zemni S. , Pena O. 
Published: November 2010

AbstractThe title compound is prepared by solid state reaction at 1400 °C and characterized by powder XRD, SEM, and magnetic measurements.
ChemInform Abstract: Enhanced Photocatalytic Activity of Mo—{001}TiO2 Core—Shell Nanoparticles under Visible Light.
Authors: Liu Xianguo , Geng Dianyu , Wang Xiaolei , Ma Song , Wang Han , Li Da , Li Baiqing , Liu Wei , Zhang Zhidong 
Published: November 2010

AbstractThe title nanoparticles are prepared by an arc‐discharge technique from Mo and Ti flakes and characterized by powder XRD, TEM, XPS, and UV/VIS spectroscopy.
ChemInform Abstract: Alkali‐Stabilized Pt‐OHx Species Catalyze Low‐Temperature Water‐Gas Shift Reactions.
Authors: Pierre Danny , et al. et al. 
Published: November 2010

AbstractA dramatic enhancement of the catalytic activity of Pt‐Al2O3 and Pt‐SiO2 for the low‐temperature (about 100 °C) water‐gas shift reaction occurs by addition of Na+ or K+ ions.
ChemInform Abstract: A Facile Construction of Bi‐ or Tricyclic Skeletons by Nickel‐Catalyzed Stereoselective Cyclization of Alkynylcycloalkanone.
Authors: Saito Nozomi , Sugimura Yasuyuki , Sato Yoshihiro 
Published: November 2010

AbstractThe conversion proceeds as a syn‐selective cyclization and the exocyclic alkene part has exclusively the (E) configuration.
ChemInform Abstract: Facile Benzo‐Ring Construction via Palladium‐Catalyzed Functionalization of Unactivated sp3 C—H Bonds under Mild Reaction Conditions.
Authors: Feng Yiqing , Wang Yuji , Landgraf Bradley , Liu Shi , Chen Gong 
Published: November 2010

AbstractGenerally, good yields are obtained for a broad scope of substrates and the reaction is tolerant to air and moisture.
ChemInform Abstract: Broensted Acid Mediated Nazarov Cyclization of Vinylallenes.
Authors: Wu Yen‐Ku , West F. G. 
Published: November 2010

AbstractIn the presence of TFA vinylsilyloxyallenes, generated from siloxy enynes, smoothly undergo Nazarov cyclization to afford cyclopentenone and/or alkylidenecyclopentanone derivatives.
ChemInform Abstract: An Intermolecular Hydroamination of Allenamides with Arylamines Catalyzed by Cationic Au(I) Salts.
Authors: Hill Anthony W. , Elsegood Mark R. J. , Kimber Marc C. 
Published: November 2010

AbstractIt allows a facile, efficient, and selective access to allylamino (E)‐enamides as useful synthons.
ChemInform Abstract: An Expeditious Copper‐Catalyzed Access to 3‐Aminoquinolinones, 3‐Aminocoumarins and Anilines Using Sodium Azide.
Authors: Messaoudi Samir , Brion Jean‐Daniel , Alami Mouad 
Published: November 2010

AbstractA direct C(sp2)—NH2 bond formation is achieved by Cu(0)—pipecolinic acid—ascorbic acid‐catalyzed reaction of 3‐bromoquinolinones (I), (III), 3‐bromocoumarins (V) and (het)aryl halides (IX) with sodium azide.
ChemInform Abstract: Iridium‐Catalyzed C—H Activation versus Directed ortho‐Metalation: Complementary Borylation of Aromatics and Heteroaromatics.
Authors: Hartmann Eduard , Kuegel Wolfgang , Parisienne‐La Salle Jean‐Christophe , Batsanov Andrei S. , Marder Todd B. , Snieckus Victor 
Published: November 2010

AbstractIr‐catalyzed borylation reactions are achieved on a variety of aryl and pyridyl amide and carbamate substrates.
ChemInform Abstract: Cobalt‐Catalyzed Benzylzincation of Alkynes.
Authors: Murakami Kei , Yorimitsu Hideki , Oshima Koichiro 
Published: November 2010

AbstractThe title reaction proceeds smoothly at ambient temperature to give tri‐ and tetrasubstituted benzylated alkenes with high regio‐ (regioisomeric ratio 90:1 to <99:1) and stereoselectivities (E:Z up to <99:1).
ChemInform Abstract: Asymmetric Conjugate Addition of Nitromethane to Enones Catalyzed by Chiral N,N′‐Dioxide—Scandium(III) Complexes.
Authors: Wang Liwei , Zhang Qi , Zhou Xin , Liu Xiaohua , Lin Lili , Qin Bo , Feng Xiaoming 
Published: November 2010

AbstractA simple to handle and highly efficient N,N′‐dioxide scandium(III) catalyst is developed for the asymmetric conjugate addition of nitromethane to chalcone analogues.
ChemInform Abstract: Remarkably Effective Phosphanes Simply with a PPh2 Moiety: Application to Pd‐Catalyzed Cross‐Coupling Reactions for Tetra‐ortho‐Substituted Biaryl Syntheses.
Authors: So Chau Ming , Chow Wing Kin , Choy Pui Ying , Lau Chak Po , Kwong Fuk Yee 
Published: November 2010

AbstractA new set of triarylphosphane ligands is prepared.
ChemInform Abstract: Gold‐Catalyzed Synthesis of Bicyclo[3.2.0]heptenes via a Formal [3 + 2]/[2 + 2]‐Annulation of Allylsilane with 4‐Methoxybut‐2‐yn‐1‐ols.
Authors: Yang Chun‐Yao , Wang Chiou‐Dong , Tian Shu‐Fan , Liu Rai‐Shung 
Published: November 2010

AbstractThe novel title reaction provides access to a variety of highly strained bicyclo[3.2.0]heptenes in high yields and diastereoselectivities.
ChemInform Abstract: An Efficient Electrochemical Method for the Paired Synthesis of Carbonyl Compounds and Homoallylic Alcohols in a Simple Home‐Made Cell
Authors: Zhang Li , Zha Zhenggen , Wang Zhiyong 
Published: November 2010

AbstractElectrochemical anodic oxidation of alcohols to carbonyl compounds followed by electrochemical cathodic allylation affords the homoallyl alcohols in good yields.
ChemInform Abstract: Asymmetric Aza‐Morita—Baylis—Hillman Reactions of Alkyl Vinyl Ketones with N‐Protected Imines or in situ Generated N‐Protected Imines.
Authors: Guan Xiao‐Yang , Wei Yin , Shi Min 
Published: November 2010

AbstractFacile and direct routes to enantioselective aza‐Morita—Baylis—Hillman adducts by the reactions of alkyl vinyl ketones with N‐protected imines and α‐amido sulfones, respectively, is developed.
ChemInform Abstract: Aqueous Extract of the Pericarp of Sapindus trifoliatus Fruits: A Novel “Green” Catalyst for the Aldimine Synthesis.
Authors: Pore Santosh , Rahsinkar Gajanan , Mote Kavita , Salunkhe Rajeshri 
Published: November 2010

AbstractThe catalytic activity of the Sapindus trifoliatus fruit extract results from the presence of saponins, which have a common pentacyclic tripernoid skeleton substituted with different carbohydrate side chains.
ChemInform Abstract: Unusual Anion Effects in the Iron‐Catalyzed Formation of 3‐Hydroxyacrylates from Aromatic Aldehydes and Ethyl Diazoacetate.
Authors: Alves Luis Goncalo , Dazinger Georg , Veiros Luis F. , Kirchner Karl 
Published: November 2010

AbstractIron trans‐dicarbonyl pincer‐type complexes are shown to catalyze the coupling of aromatic aldehydes with ethyl diazoacetate to give the products (III) or (V) resulting from an intermediate aryl‐shift and the direct coupling products (VI).
ChemInform Abstract: Decarboxylative Acylation of Arenes with α‐Oxocarboxylic Acids via Palladium‐Catalyzed C—H Activation.
Authors: Li Mingzong , Ge Haibo 
Published: November 2010

AbstractCross‐coupling of unactivated arenes with aromatic α‐carboxylic acids and an aliphatic analogue (IIi) renders possible a novel access to aryl ketones.
ChemInform Abstract: Acid—Base Organocatalysts for the Aza‐Morita—Baylis—Hillman Reaction of Nitroalkenes.
Authors: Takizawa Shinobu , Horii Atsushi , Sasai Hiroaki 
Published: November 2010

AbstractNew chiral catalysts for the enantioselective coupling of conjugated nitroalkenes and imines are developed.
ChemInform Abstract: Iron‐Catalyzed Regio‐ and Stereoselective Head‐to‐Tail Dimerization of Styrenes.
Authors: Cabrero‐Antonino Jose R. , Leyva‐Perez Antonio , Corma Avelino 
Published: November 2010

AbstractCationic Fe(III) salts catalyze the regioselective head‐to‐tail dimerization of styrene derivatives (I), (III) to afford the dimers (II) and (IV), resp., in good yields and excellent E‐selectivity.
ChemInform Abstract: A Novel Process for Selective Ruthenium‐Catalyzed Oxidation of Naphthalenes and Phenols.
Authors: Wienhoefer Gerrit , Schroeder Kristin , Moeller Konstanze , Junge Kathrin , Beller Matthias 
Published: November 2010

AbstractAn improved method is presented for the Ru‐catalyzed hydrogen peroxide oxidation of naphthalenes, naphthols and phenols to the corresponding quinones.
ChemInform Abstract: Rearrangement of 2,3‐Epoxy Alcohol Dimethylthiocarbamate Derivatives. Synthesis of 2,3‐Epithio Alcohol Derivatives under Mild Conditions.
Authors: Kalicki Przemyslaw , Karchier Michal , Michalak Karol , Wicha Jerzy 
Published: November 2010

AbstractTreatment of 2,3‐epoxy alcohols of type (I), (V), and (VIII) with Cl‐CS‐NMe2 results in formation of the corresponding thiocarbamate derivatives which are unstable and undergo rearrangement to 2,3‐epithio alcohol derivatives at room temperature.
ChemInform Abstract: Tetrathiomolybdate Mediated Rearrangement of Aziridinemethanol Tosylates: A Thia‐aza‐Payne Rearrangement.
Authors: Sureshkumar Devarajulu , Koutha Srinivasamurthy Koutha , Ganesh Venkataraman , Chandrasekaran Srinivasan 
Published: November 2010

AbstractThe rearrangement affords thiiranes.
ChemInform Abstract: N‐Benzyloxymalimide for an Easy Access to 5‐Alkyl‐3‐pyrrolin‐2‐ones: Asymmetric Synthesis of the Mixed Imide Substructure of the Potent Immunosuppressant Microcolin B.
Authors: Ye Zhao‐Bao , Chen Jie , Meng Wei‐Hua , Huang Pei‐Qiang 
Published: November 2010

AbstractN‐benzyloxymalimide (III) is synthesized as a novel chiral building block.
ChemInform Abstract: Exploiting the Chemistry of Strained Rings: Synthesis of Indoles via Domino Reaction of Aryl Iodides with 2H‐Azirines.
Authors: Candito David A. , Lautens Mark 
Published: November 2010

AbstractIn the case of substrates (IV) the azirine is completely consumed, whereas the aryl iodide is recovered.
ChemInform Abstract: Asymmetric 1,3‐Dipolar Cycloaddition Reactions of Azomethine Imines with Acrolein Catalyzed by L‐Proline and Its Derivatives.
Authors: Suga Hiroyuki , Arikawa Tadashi , Itoh Kennosuke , Okumura Yukihisa , Kakehi Akikazu , Shiro Motoo 
Published: November 2010

Abstract(S)‐Indoline‐2‐carboxylic acid as catalyst shows high exo‐selectivity, while with L‐proline exo‐products are favored due to isomerization of the exo‐ to the endo‐cycloadducts.