bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Lactol‐Ene Reaction: An Efficient Access to the Synthesis of 22R,25‐ Dihydroy Steroid Side Chains.
Authors: MIKAMI K. , KISHINO H. , MATSUEDA H. , LOH T.‐P. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Racemic myo‐Inositol 1,4,5‐Trisphosphate 3‐O‐ Methylenecarboxylate (VII), a Ca2+‐Mobilising myo‐Inositol 1,3,4,5‐ Tetrakisphosphate Analogue.
Authors: LIU C. , THOMAS N. F. , POTTER B. V. L. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Syntheses of Ethyl Z‐ and E‐Octa‐2,6‐ dienopyranosiduronates from Ethyl 2,4‐Dideoxy‐α‐D‐erythro‐hex‐2‐ enopyranoside.
Authors: GOMEZ A. M. , LOPEZ J. C. , FRASER‐REID B. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Carbocyclic Analogues of 1‐β‐D‐Psicofuranosyl Nucleosides. psico‐Cyclopentenyladenosine (Psicoplanocin A) and psico‐ Cyclopentenylcytosine.
Authors: BODENTEICH M. , MARQUEZ V. E. , BARCHI J. J. JUN. , HALLOWS W. H. , GOLDSTEIN B. M. , DRISCOLL J. S. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ultraviolet Resonance Raman Spectra of Ribosyl C(1′)‐Deuterated Purine Nucleosides: Evidence of Vibrational Coupling Between Purine and Ribose Rings
Authors: TOYAMA A. , TAKINO Y. , TAKEUCHI H. , HARADA I. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Route to Functionalized cis‐Hydrindanes from Tricyclo( 5.2.1.02,6)decan‐10‐ones. A Total Synthesis of (.+‐.)‐Coronafacic Acid.
Authors: MEHTA G. , PRAVEEN M. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies of the Rutamycins. Construction of the C1‐C15 Subunit (II) of Rutamycin B.
Authors: WHITE J. D. , PORTER W. J. , TILLER T. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Local Monitoring of Absolute NO2 Concentrations in Ambient Air by Multipass Absorption Spectroscopy.
Authors: ARMERDING W. , WALTER J. , RUEGER CHR. , SPIEKERMANN M. , COMES F. J. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbon, Silicon, Germanium, Tin and Lead
Authors: ARMITAGE D. A. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Laser‐Matter Interaction in Intense Laser Fields
Authors: LOMPRE L. A. , MONOT P. , AUGUSTE T. , MAINFRAY G. , MANUS C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitric Oxide Catalysis in Automotive Exhaust Systems
Authors: TAYLOR K. C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: State‐Resolved Simple Bond‐Fission Reactions: Experiment and Theory
Authors: REISLER H. , WITTIG C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magneto‐Structural Correlations in Dimeric Copper(II) Carboxylates
Authors: OHBA S. , KATO M. , TOKII T. , MUTO Y. , STEWARD O. W. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Entry to Naturally Occurring 5‐Alkenyl α,β‐Unsaturated δ‐Lactones from D‐Glucose: Syntheses of (+)‐Acetylphomalactone and (+)‐Asperlin.
Authors: GOMEZ A. M. , LOPEZ DE URALDE B. , VALVERDE S. , LOPEZ J. C. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Discovery of LB30057, a Benzamidrazone‐Based Selective Oral Thrombin Inhibitor.
Authors: OH Y. S. , KIM S. , ET AL. ET AL. 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation and Crystal Structure of Triammonium‐trisulfimide (NH4)3(NSO2)3.
Authors: Leben Christiane , Jansen Martin 
Published: September 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro
Authors: Boudiffa Maya , Wade-Gueye Ndéye Marième , Guignandon Alain , Vanden-Bossche Arnaud , Sabido Odile , Aubin Jane E , Jurdic Pierre , Vico Laurence , Lafage-Proust Marie Hélène , Malaval Luc 
Published: September 2010

Abstract
Bone sialoprotein (BSP) and osteopontin (OPN) belong to the small integrin-binding ligand N-linked glycoprotein (SIBLING) family, whose members interact with bone cells and bone mineral. Previously, we showed that BSP knockout (BSP−/−) mice have a higher bone mass than wild type (BSP+/+) littermates, with very low bone-formation activity and reduced osteoclast surfaces and numbers. Here we report that approximately twofold fewer tartrate-resistant acid phosphatase (TRACP)–positive cells and approximately fourfold fewer osteoclasts form in BSP−/− compared with BSP+/+ spleen cell cultures. BSP−/− preosteoclast cultures display impaired proliferation and enhanced apoptosis. Addition of RGD-containing proteins restores osteoclast number in BSP−/− cultures to BSP+/+ levels. The expression of osteoclast-associated genes is markedly altered in BSP−/− osteoclasts, with reduced expression of cell adhesion and migration genes (αV integrin chain and OPN) and increased expression of resorptive enzymes (TRACP and cathepsin K). The migration of preosteoclasts and mature osteoclasts is impaired in the absence of BSP, but resorption pit assays on dentine slices show no significant difference in pit numbers between BSP+/+ and BSP−/− osteoclasts. However, resorption of mineral-coated slides by BSP−/− osteoclasts is markedly impaired but is fully restored by coating the mineral substrate with hrBSP and partly restored by hrOPN coating. In conclusion, lack of BSP affects both osteoclast formation and activity, which is in accordance with in vivo findings. Our results also suggest at least some functional redundancy between BSP and OPN that remains to be clarified. © 2010 American Society for Bone and Mineral Research.
Theoretische Chemie 1996
Authors: Kaupp Martin , Jug Karl , Häser Marco 
Published: September 2010

AbstractDie Anwendung von Dichtefunktional‐und ab initio‐Methoden auf molekulare Übergangsmetallsysteme, die semiempirische Theorie größerer Systeme, wie Biomoleküle, Cluster und Festkörper, sowie das Potential theoretischer Methoden für die Chemie der Hauptgruppen, die Interpretation von NMR‐Spektren und das Verständnis bestimmter chemischer Phänomene sind diesmal Schwerpunkte des Trendberichts.
Sechs Aufgaben für die Computer‐Chemie
Authors: Niskanen Elina 
Published: September 2010

AbstractChemie, Information und Computer, diese drei Schlagworte verknüpfen das Know‐how von Computerexperten mit dem der Chemiker. Wo sind die zukunftsträchtigen Themen? Welche Vorteile Ziehen Chemiker aus der Kombination?
NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia
Authors: Shiba Norio , Kanazawa Takashi , Park Myoung‐ja , Okuno Haruna , Tamura Kazushi , Tsukada Shota , Hayashi Yasuhide , Arakawa Hirokazu 
Published: September 2010

AbstractA 6‐year‐old Japanese female was diagnosed as having myeloid/NK cell precursor acute leukemia (MNKL) using immunocytochemical analysis. The patient was treated by cord blood transplantation from an HLA 1‐locus mismatched unrelated donor after chemotherapy comprising cytosine arabinoside, idarubicin, etoposide, and L‐asparaginase. We detected a nonsense mutation, C7412A, resulting in S2471X, where X is a terminal codon, in the PEST domain of NOTCH1 in this patient. The presence of the NOTCH1 activating mutation in MNKL might suggest a possible role in the leukemogenesis of MNKL. Pediatr Blood Cancer. 2010;55:1406–1409. © 2010 Wiley‐Liss, Inc.
Emerging clinical applications in cardiovascular pharmacogenomics
Authors: Damani Samir B. , Topol Eric J. 
Published: September 2010

AbstractOver one‐fourth of the 36 million annual outpatient prescriptions filled in the United States are known to have human genomic biomarker information available that predicts drug safety and efficacy, or both. However, to date, we have not systematically implemented strategies to effectively use this data in clinical practice to improve patient outcomes. Part of the difficulty has stemmed from the only modest predictive capacity of previously identified gene variants, lack of replication of data in multiple studies, and the hesitancy of the clinical community to translate data gleaned from basic and translational research to routine clinical practice. Now, additional key variants that strongly impact drug absorption, metabolism, and excretion are rapidly surfacing through the use of genome‐wide association technology. Most importantly, these variants are being validated in independent cohorts of thousands of cases and controls. In the near future, the dramatic reduction in the cost of DNA sequencing will lead to further insight into the common and rare genetic variants that strongly predict our individual response to commonly used medications. The clinical community will need to be prepared to utilize this vital data in aiding their selection of the right drug for the right patient if we expect to significantly reduce the ever increasing burden of societies' most common diseases. Herein, we detail the most clinically compelling and robust examples of pharmacogenomics emerging in the field of cardiovascular disease and hopefully foretell how cardiovascular disease might be treated in the era of genomic medicine. WIREs Syst Biol Med 2011 3 206–215 DOI: 10.1002/wsbm.113This article is categorized under:

Physiology > Mammalian Physiology in Health and Disease
Translational, Genomic, and Systems Medicine > Therapeutic Methods
Using a Plan‐Do‐Study‐Act Cycle to Introduce a New OR Service Line
Authors: Nakayama Don K. , Bushey Timothy N. , Hubbard Irene , Cole Dawn , Brown Amanda , Grant Timothy M. , Shaker Issam J. 
Published: September 2010

AbstractIn 2008, a multidisciplinary team at the Medical Center of Georgia, Macon, began a one‐year Plan‐Do‐Study‐Act (PDSA) cycle to implement a high‐quality pediatric surgery service line. The PDSA team defined goals, objectives, and measurable performance metrics and then reviewed cases and aggregated data monthly to identify and improve clinical, process, instrument, and supply problems as well as patient transfer issues. The PDSA cycle led to improvements in team performance, communication, and patient transfer and decreased the number of problems associated with instruments, supplies, equipment, and surgeon tardiness.
Perioperative Care of the Morbidly Obese Patient in the Lithotomy Position
Authors: Bennicoff Geraldine 
Published: September 2010

AbstractThe lithotomy position is used daily in the OR to position patients for vaginal, rectal, and urologic procedures. Use of this position requires a careful nursing assessment to ensure that the patient can tolerate having his or her legs placed in the stirrups and to ensure that no pressure points exist for the duration of the surgery. Caring for a patient who is morbidly obese and who requires surgery in the lithotomy position can be especially challenging, and the possibility of injury to the patient or staff members should be considered. A case study involving the care of a patient who weighed almost 600 lb undergoing surgery in the lithotomy position demonstrates ways to provide safe care for this type of challenging patient.
Disease progression model for cognitive deterioration from Alzheimer's Disease Neuroimaging Initiative database
Authors: Ito Kaori , Corrigan Brian , Zhao Qinying , French Jonathan , Miller Raymond , Soares Holly , Katz Elyse , Nicholas Timothy , Billing Bill , Anziano Richard , Fullerton Terence 
Published: September 2010

BackgroundA mathematical model was developed to describe the longitudinal response in Alzheimer's Disease Assessment Scale‐cognitive (ADAS‐cog) obtained from the Alzheimer's Disease Neuroimaging Initiative.MethodsThe model was fit to the longitudinal ADAS‐cog scores from 817 patients. Risk factors (age, apolipoprotein ɛ4 [APOE ɛ4] genotype, gender, family history of AD, years of education) and baseline severity were tested as covariates.ResultsRate of disease progression increased with baseline severity. Age, APOE ɛ4 genotype, and gender were identified as potential covariates influencing disease progression. The rate of disease progression in patients with mild to moderate AD was estimated as approximately 5.5 points/yr.ConclusionsA disease progression model adequately described the natural decline of ADAS‐cog observed in Alzheimer's Disease Neuroimaging Initiative. Baseline severity is an important covariate to predict a curvilinear rate of disease progression in normal elderly, mild cognitive impairment, and AD patients. Age, APOE ɛ4 genotype, and gender also influence the rate of disease progression.
Late Permian and Early Triassic magmatic pulses in the Angara–Taseeva syncline, Southern Siberian Traps and their possible influence on the environment
Authors: Paton M.T. , Ivanov A.V. , Fiorentini M.L. , McNaughton N.J. , Mudrovska I. , Reznitskii L.Z. , Demonterova E.I. 
Published: September 2010

Abstract
Recently it has been suggested that the major influence on the environment from Siberian Traps magmatism was due to the interaction of magma and organic-rich shale and petroleum-bearing evaporites, with the subsequent creation and outburst of toxic gases (Siberian gas venting: SGV model). In part this idea was supported by a U-Pb age of 252.0 ± 0.4 Ma for one of the dolerite sills in the southeastern Siberian Traps: the age corresponds to the Permo-Triassic boundary and its known mass extinctions of biota. In this study two other dolerite sills were dated using zircons by the U-Pb SHRIMP method at 254.2 ± 2.3 Ma and 249.6 ± 1.5 Ma. The former age is in agreement within error with the age previously published for the dolerite sills, whereas the latter age is in agreement with U-Pb ages published for lava and intrusions from the northern Siberian Traps. The new ages corresponds to the Cahngshingian/Wuchiapingian or Permian/Triassic and Spathian/Smithian boundaries, respectively. Review of 40Ar/39Ar and U-Pb SHRIMP ages previously published for the southeastern Siberian Traps shows that three other pulses of magmatism probably took place at respectively Anisian/Spathian, Late/Middle Anisian and Landian/Anisian boundaries. Thus it is possible that the SVG model can be applied also to lesser biotic extinctions and recoveries in proximity and aftermath to the main Permo-Triassic extinction.
The relative value of concentrates and roughage for fattening cattle
Authors: Levy D. , Holzer Z. 
Published: September 2010

SUMMARYIn three similar experiments, 2 or 3 kg of a commercial concentrate mixture, forming part of a high concentrate ration, were replaced by an equal weight of dry matter of one of four roughages: hay, straw, silage and green soilage.The metabolizable energy content of the concentrate was 2-4 Mcal/kg. Expected daily gain was calculated according to the following energy systems: Scandinavian feed units (SFU), starch equivalent (SE), total digestible nutrients (TDN), the U.K. Agricultural Research Council system (ARC), and the U.S. National Research Council net energy system (NRC).The replacement of 2 kg of concentrate significantly reduced daily gain only in the straw treatment. Reduction of the fat content of the carcasses was significant for all roughage treatments. The differences between the observed daily gain and the expected, as calculated by the SFU, SE and NRC systems, were highly significant, while those between the observed and those cal culated by the TDN and ARC systems were not significant. The TDN system overestimated the nutritional value of the roughages, while the SFU and SE systems underestimated it.
The effects of variations in the energy concentration and protein source of complete diets for beef cattle
Authors: Broadbent P. J. , Ball C. , Dodsworth T. L. 
Published: September 2010

SUMMARYTwelve British Friesian and 12 Ayrshire castrated male calves were fed ad libitum one of three complete diets of differing energy concentration from approximately 140 to 410 kg live weight. Differences in energy concentration of the diets were achieved by inclusion of different proportions of wet distiller's grains (WDG). Increasing the proportion of WDG in the diet caused reductions in performance. This effect was more marked with the Friesians than with the Ayrshires. The treatments had small and generally non-significant effects on carcass conformation and composition.
Influence of energy and protein concentration in the diet on the performance of growing pigs 1. Response to protein intake on a high-energy diet
Authors: Cooke R. , Lodge G. A. , Lewis D. 
Published: September 2010

SUMMARYSixty gilts by Landrace sires out of Large White × Landrace females were allocated on the basis of litter relationship and initial weight to six treatments involving the individual feeding of six dietary protein levels, 15·5%, 17·4%, 20·2%, 22·3%, 25·3% and 27·3% crude protein (CP), at a common energy level of approximately 3500 kcal/kg DE, from 23 to 59 kg live weight. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. There were significant increases in growth rate and efficiency of feed conversion from the 15·5% to the 17·4% CP diets and significant reductions in both from the 25·3 % to the 27·3 % CP diets. Carcass lean by dissection increased linearly (r = 0·976) and fat decreased linearly (r = −0·992) with dietary protein increment over the full range studied. As best growth performance and maximum lean content were attained at different dietary CP levels, a combined measure of daily lean deposition was calculated; this indicated that maximum rate of lean growth and efficiency of feed conversion to lean were reached on the 22·3% CP level. In terms of efficiency of utilization of nutrients, maximum retentions of both DE and DCP in the edible part of the carcass appeared to be attained on the two lowest dietary protein levels.
Influence of energy and protein concentration in the diet on the performance of growing pigs 2. Differing nutrient density at a constant energy: protein ratio
Authors: Lodge G. A. , Cundy M. E. , Cooke R. , Lewis D. 
Published: September 2010

SUMMARYForty-eight gilts by Landrace sires on Large White × Landrace females were randomly allocated to eight pens and within pens to six treatment groups involving three diets and two levels of feeding from 23 to 59 kg live weight. All diets were formulated to have approximately the same ratio of digestible energy to crude protein (160 kcal DE/unit % CP) but different energy and protein concentrations: (A) 3500 kcal/kg DE and 21 % CP, (B) 3150 kcal/kg DE and 19% CP, and (C) 2800 kcal/kg DE and 17% CP. Amino acid balance was maintained relatively constant with synthetic lysine, methionine and tryptophan. The levels of feeding were such that the lower level of diet A allowed an intake of energy and protein similar to the higher level of diet B, and the lower level of B was similar to the higher level of C.On the lower level of feeding, growth rate, efficiency of feed conversion and carcass fat content increased linearly with each increment in nutrient concentration; on the higher level of feeding growth rate and EFC increased from diet C to B but not from B to A, whereas carcass fat content increased linearly with diet from the lowest to the highest concentration. There was a non-significant tendency for the higher density diets at a similar level of nutrient intake to give better EFC and fatter carcasses than the lower density diets.