bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental impact of phytobiotic additives on greenhouse gas emission reduction, rumen fermentation manipulation, and performance in ruminants: an updated review
Authors: Ahmed Mariam G. , Elwakeel Eman A. , El-Zarkouny Samir Z. , Al-Sagheer Adham A. 
Published: May 2024

AbstractRuminal fermentation is a natural process involving beneficial microorganisms that contribute to the production of valuable products and efficient nutrient conversion. However, it also leads to the emission of greenhouse gases, which have detrimental effects on the environment and animal productivity. Phytobiotic additives have emerged as a potential solution to these challenges, offering benefits in terms of rumen fermentation modulation, pollution reduction, and improved animal health and performance. This updated review aims to provide a comprehensive understanding of the specific benefits of phytobiotic additives in ruminant nutrition by summarizing existing studies. Phytobiotic additives, rich in secondary metabolites such as tannins, saponins, alkaloids, and essential oils, have demonstrated biological properties that positively influence rumen fermentation and enhance animal health and productivity. These additives contribute to environmental protection by effectively reducing nitrogen excretion and methane emissions from ruminants. Furthermore, they inhibit microbial respiration and nitrification in soil, thereby minimizing nitrous oxide emissions. In addition to their environmental impact, phytobiotic additives improve rumen manipulation, leading to increased ruminant productivity and improved quality of animal products. Their multifaceted properties, including anthelmintic, antioxidant, antimicrobial, and immunomodulatory effects, further contribute to the health and well-being of both animals and humans. The potential synergistic effects of combining phytobiotic additives with probiotics are also explored, highlighting the need for further research in this area. In conclusion, phytobiotic additives show great promise as sustainable and effective solutions for improving ruminant nutrition and addressing environmental challenges.
Estimation of the level of anthropogenic impact based on the determination of radionuclides and heavy metals in sediments taken from Rybnik reservoir, Poland
Authors: Szarłowicz Katarzyna , Baran Agnieszka , Wójs Karolina , Wójcik Sylwia 
Published: May 2024

AbstractThe aim of the study was to estimate the degree of anthropogenic risk by evaluating the level of the contamination of sediments collected from the Rybnik reservoir. The results of the determination of radionuclides (137Cs, 40K, 228Th, 228Ra, 226Ra, 210Pb, 238U) and heavy metals (Zn, Cd, Pb, Cu, Cr, Ni) were presented. The Rybnik reservoir is located in a highly urbanised area, the Lower Silesian Voivodeship in Poland. Radionuclides (137Cs, 40K, 228Th, 228Ra, 226Ra, 210Pb, 238U) were measured using gamma spectrometry. The heavy metal (Zn, Cd, Pb, Cu, Ni and Cr) content was determined using an inductively coupled plasma optical emission spectrophotometer (ICP-OES). The classification of sediment pollution was made on the basis of geochemical and ecotoxicological indices. Radioactivity was varied with the highest for 40K (more than 200 Bq·kg−1). The concentrations for the remaining radionuclides were mostly below 20 Bq·kg−1. At the inlet zone (no. 9) an increase in radioactivity of each radioisotope was observed. The values of heavy metals from the lowest to the highest total amount in the sediments were as follows: Cd < Cr < Pb < Ni < Cu < Zn. The sediments of the reservoir are largely contaminated with Cu, but the sediments generally are contaminated to an average degree. Most pollutants accumulate in the inlet zone and near the dam wall. The content of artificial radionuclides, as well as the geochemical and ecological indicators used, can serve as an indicator of the level of anthropopressure in the vicinity of the Rybnik reservoir.
Occurrence and sources of hormones in water resources—environmental and health impact
Authors: Grzegorzek Martyna , Wartalska Katarzyna , Kowalik Robert 
Published: May 2024

AbstractWithin recent years, hormones have become emergent contaminants in the water environment. They easily accumulate in living organisms which in effect leads to numerous health problems (endocrine-disrupting mechanism is one of the most known toxic effects). Microbial resistance to antibiotics also became one of the emergent issues related to hormone presence. It was shown that the most common in the environment occur estrogens (E1, E2, E3, and EE2). It has been proven that large amounts of hormones are released from aquaculture as well as from wastewater treatment plants (due to the relatively low separation efficiency of conventional wastewater treatment processes). Within the article’s scope, the literature review was performed. The analysis was regarding the characterization of the hormone substances present in the environment, their influence on living organisms and the environment, as well as its potential sources classification.
A Very Compact Metamaterial-Based Triple-Band Sensor in Terahertz Spectrum as a Perfect Absorber for Human Blood Cancer Diagnostics
Authors: Hamza Musa N. , Abdulkarim Yadgar I. , Saeed Salah Raza , Hamad Muhamad A. , Muhammadsharif Fahmi F. , Bakır Mehmet , Appasani Bhargav , Haxha Shyqyri 
Published: May 2024

AbstractNowadays, early cancer identification and surveillance have become vital problems. This research paper explores the development of a small, three-band sensor harnessing the potential of terahertz (THz) technology and metamaterials (MTMs) to diagnose blood cancer. The proposed sensor holds the promise of a paradigm shift in the diagnosis of blood cancer by offering a non-invasive and highly accurate approach. Terahertz radiation, occupying the unique “THz gap” in the electromagnetic spectrum, is now accessible due to recent technological breakthroughs. This work simplifies the design of multiple-band metamaterial absorbers, enhancing their effectiveness and expanding their sensing capabilities. Through the integration of THz technology, metamaterial engineering, and cancer detection, the suggested sensor seeks to launch a new phase of rapid, precise, and non-invasive blood cancer diagnosis. The proposed structure is capable of distinguishing cancer and normal cell with 1 GHz sensitivity, which would be more pronounced when we consider the THz technology devices. This work represents a significant step forward in non-invasive, accurate diagnostics for blood cancer, promising to revolutionize the way this disease is diagnosed and treated. The proposed novel strategy has a lot of promise to advance medical diagnostics and enhance patients’ outcomes.
Glycyrrhizic Acid Alleviates Semen Strychni-Induced Neurotoxicity Through the Inhibition of HMGB1 Phosphorylation and Inflammatory Responses
Authors: Yu Changwei , Xiang Yalan , Zhang Min , Wen Jing , Duan Xiaoyu , Wang Lu , Deng Gongying , Fang Pingfei 
Published: May 2024

Abstract
The neurotoxicity of Semen Strychni has been reported recently in several clinical cases. Therefore, this study was conducted to investigate the role of HMGB1 in a model of neurotoxicity induced by Semen Strychni and to assess the potential alleviating effects of glycyrrhizic acid (GA), which is associated with the regulation of HMGB1 release. Forty-eight SD rats were intraperitoneally injected with Semen Strychni extract (175 mg/kg), followed by oral administration of GA (50 mg/kg) for four days. After treatment of SS and GA, neuronal degeneration, apoptosis, and necrosis were observed via histopathological examination. Inflammatory cytokines (TNF-α and IL-1β), neurotransmitter associated enzymes (MAO and AChE), serum HMGB1, nuclear and cytoplasmic HMGB1/ph-HMGB1, and the interaction between PP2A, PKC, and HMGB1 were evaluated. The influence of the MAPK pathway was also examined. As a result, this neurotoxicity was characterized by neuronal degeneration and apoptosis, the induction of pro-inflammatory cytokines, and a reduction in neurotransmitter-metabolizing enzymes. In contrast, GA treatment significantly ameliorated the abovementioned effects and alleviated nerve injury. Furthermore, Semen Strychni promoted HMGB1 phosphorylation and its translocation between the nucleus and cytoplasm, thereby activating the NF-κB and MAPK pathways, initiating various inflammatory responses. Our experiments demonstrated that GA could partially reverse these effects. In summary, GA acid alleviated Semen Strychni-induced neurotoxicity, possibly by inhibiting HMGB1 phosphorylation and preventing its release from the cell.
Attachment in Young Adults and Life Satisfaction at Age 30: A Birth Cohort Study
Authors: Blake Julie A. , Thomas Hannah J. , Pelecanos Anita M. , Najman Jake M. , Scott James G. 
Published: May 2024

Abstract
Background
Satisfying close relationships are associated with higher levels of life satisfaction throughout the life course. Despite the fundamental role of attachment style in close relationships, few studies have longitudinally examined the association between attachment style in young adults with later life satisfaction.

Method
Data from 2,088 participants in a longitudinal birth cohort study were examined. At 21-years, participants completed the Attachment Style Questionnaire which comprises five domains reflective of internal working models of interpersonal relationships and attachment style: confidence (security), discomfort with closeness and relationships as secondary (avoidance), need for approval and preoccupation with relationships (anxiety). At 30-years, participants self-reported their overall life satisfaction. Linear regression was used to longitudinally examine the association between attachment domains at 21-years and life satisfaction at age 30.

Results
After adjustments, confidence was positively associated with life satisfaction (β = 0.41, 95% CI 0.25–0.56, p < 0.001), while need for approval was negatively associated with life satisfaction (β = -0.17, 95% CI -0.30 – -0.04, p < 0.001). Low income at 21, caring for a child by age 21, and leaving the parental home at 16-years or under were negatively associated with life satisfaction at 30-years.

Conclusion
Young adult attachment style is associated with later life satisfaction, particularly through confidence in self and others. Promoting positive internal working models of interpersonal relationships and fostering greater confidence in self and others in adolescence may be an effective strategy for improving life satisfaction later in life.
An optimal advertising model with carryover effect and mean field terms
Authors: Gozzi Fausto , Masiero Federica , Rosestolato Mauro 
Published: May 2024

AbstractWe consider a class of optimal advertising problems under uncertainty for the introduction of a new product into the market, on the line of the seminal papers of Vidale and Wolfe (Oper Res 5:370–381, 1957) and Nerlove and Arrow (Economica 29:129–142, 1962). The main features of our model are that, on one side, we assume a carryover effect (i.e. the advertisement spending affects the goodwill with some delay); on the other side we introduce, in the state equation and in the objective, some mean field terms that take into account the presence of other agents. We take the point of view of a planner who optimizes the average profit of all agents, hence we fall into the family of the so-called “Mean Field Control” problems. The simultaneous presence of the carryover effect makes the problem infinite dimensional hence belonging to a family of problems which are very difficult in general and whose study started only very recently, see Cosso et al. [Ann Appl Probab 33(4):2863–2918, 2023]. Here we consider, as a first step, a simple version of the problem providing the solutions in a simple case through a suitable auxiliary problem.
The effect of bee drone brood on the motility and viability of stallion spermatozoa—an in vitro study
Authors: Lenický Michal , Sidor Ewelina , Dianová Lucia , Tirpák Filip , Štefunková Nikola , Dżugan Małgorzata , Halo Marko , Halo Marko , Slanina Tomáš , Urban Iveta , Bažány Denis , Greń Agnieszka , Roychoudhury Shubhadeep , Schneir Eric Rendon , Massányi Peter 
Published: May 2024

AbstractBee drone brood is a beehive by-product with high hormonal activity used in natural medicine to treat male infertility. The aim of the study was to assess the effect of drone brood on stallion spermatozoa during a short-term incubation for its potential use in the equine semen extenders. Three different forms of fixed drone brood (frozen (FR), freeze-dried (FD), and dried extract (DE)) were used. Solutions of drone brood were compared in terms of testosterone, protein, total phenolic content, and antioxidant activity. The stallion semen was diluted with prepared drone brood solutions. The computer-assisted semen analysis (CASA) method was employed to evaluate the movement characteristics of the diluted ejaculate. To determine spermatozoa viability, the mitochondrial toxicity test (MTT) and Alamar Blue test were performed. In terms of testosterone content and antioxidant activity, a close likeness between FR and FD was found whereas DE’s composition differed notably. FR had a positive effect mainly on progressive motility, but also on sperm distance and speed parameters after 2 and 3 h of incubation. On the contrary, FD and DE acted negatively, depending on increasing dose and time. For the first time, a positive dose-dependent effect of fixed drone brood on spermatozoa survival in vitro was demonstrated.
Graphical Abstract
On the Equicontinuity of Generalized Quasiconformal Mappings by Prime Ends
Authors: Ilkevych Nataliya , Sevost’yanov Evgeny , Ukhlov Alexander 
Published: May 2024

AbstractWe study mappings satisfying the inverse Poletsky type inequality with respect to a non-conformal modulus. It was prove that such mappings, with some additional conditions, have a continuous extension to the boundary in terms of prime ends and form equicontinuous families of mappings.
Exploring the enablers for building resilience in solar photovoltaic Energy supply chains
Authors: Erol Ismail , Peker Iskender , Benli Tolga , Ar Ilker Murat , Searcy Cory 
Published: May 2024

AbstractA solar photovoltaic energy supply chain (SPvESC) is a global network with several linkages, including mineral and metal mining, material processing, and module and panel manufacturing. Due to the wide range of uncertainties and the unfavorable environmental effects associated with current linear business models, this global network is vulnerable to disruptions. Strengthening the resilience of SPvESCs is crucial for addressing any disturbances. This requires identifying the key enablers of resilience in SPvESCs, an area that has been understudied in the existing literature. An enabler is an aspect that facilitates the achievement of a goal by another aspect. This research contributes to the existing literature by systematically investigating the enablers for SPvESCs to achieve resilience. Thus, the objective of this analysis is to identify enablers that have the potential to enhance the resilience of SPvESCs in Türkiye. This was done by applying the Nominal Group Technique (NGT) in conjunction with a review of the current literature. Neutrosophic (N)-DEMATEL was then utilized to determine the relationships between the identified enablers. Finally, the results were validated using N-DELPHI. The results revealed that sensing and seizing new business models, adaptability to changes in novel energy generation and information technologies, and business contingency plans for natural and man-made disasters were the most influential enablers. The findings provide implications for practitioners, policymakers, and researchers to help ensure improved resilience in SPvESCs.
HER2/neu 655 polymorphism, trastuzumab-induced cardiotoxicity, and survival in HER2-positive breast cancer patients
Authors: Blancas Isabel , Linares-Rodríguez Marina , Martín-Bravo Celia , Gómez-Peña Celia , Rodríguez-Serrano Fernando 
Published: May 2024

Abstract
Purpose
HER2 overexpression in breast cancer correlates with poor outcomes. The incorporation of Trastuzumab into the treatment regimen has notably improved patient prognoses. However, cardiotoxicity emerges in approximately 20% of patients treated with the drug. This study aims to investigate the association between the HER2 655 A > G polymorphism, Trastuzumab-induced cardiotoxicity, and patient survival.

Methods
The study involved 88 patients treated with Trastuzumab. Cardiotoxicity, defined as a reduction in left ventricular ejection fraction (LVEF) from baseline or the emergence of clinical signs of congestive heart failure, was identified during treatment follow-up. Genotyping of HER2 655 A > G employed TaqMan SNP technology.

Results
Genotype frequencies of HER2/neu 655 (53 AA, 32 AG, and 3 GG) were consistent with Hardy–Weinberg equilibrium. No significant differences were observed in mean baseline LVEF between patients who developed cardiotoxicity and those who did not. Within these groups, neither AA nor AG genotypes showed an association with changes in mean baseline or reduced LVEF levels. Logistic regression analysis, adjusted for hormonal status and anthracycline treatment, revealed that AG genotype carriers face a significantly higher risk of cardiotoxicity compared to AA carriers (OR = 4.42; p = 0.037). No association was found between the HER2/neu 655 A > G polymorphism and disease-free or overall survival, regardless of whether the data was adjusted for stage or not.

Conclusion
HER2 655 A > G polymorphism is significantly linked to an increased risk of Trastuzumab-induced cardiotoxicity but does not correlate with variations in disease-free survival or overall survival rates.
Neglected Components in Dominant Accounts of a Good Life? — Disagreements among Maasai Pastoralists
Authors: Pissarskoi Eugen , Singo Leiyo 
Published: May 2024

Abstract
Lists of basic needs necessary for a decent human life have found their way into approaches to sustainable development such as the “Safe and Just Space for Humanity” framework. The “dominant” conceptions of a decent human life have been criticised by social groups which find themselves at the margins of public debates such as the Degrowth or Post-colonial movements. According to the latter, the dominant conceptions neglect certain values which are necessary constituents of a decent human life: meaningful activities, convivial activities, and relationships of certain quality (love, respect, harmony, care) towards human and other-than-human beings. With this paper, we present results of interviews with male Maasai pastoralists in a village in Northern Tanzania in which we elicited what they consider as requirements for a good human life. According to our results, Maasai pastoralists disagree about the necessary constituents of a decent human life as well, replicating the controversy from the international debates between the proponents of the dominant approaches and their critics from Post-colonial and Degrowth movements.
A Foot in the Australian Employment Door: A Qualitative Study of Highly Skilled Migrant Women
Authors: Singh Jasvir Kaur Nachatar , Mutum Juliana 
Published: May 2024

AbstractIn the recent years, Australia has been seeking highly skilled migrants to close the skill gap and increase economic participation in the labour market. Although women are predominant among recent migrants in Australia, they experience higher unemployment rates than male migrants. Previous research has shown that one key challenge they face is their family responsibilities that hinder them in the employment market. In this study, factors in gaining Australian employment for highly skilled migrant women are highlighted. Drawing on 27 semi-structured qualitative interviews with such women, the analysis identified three main factors in gaining employment in Australia: (1) leveraging social capital; (2) accumulation of human capital; and (3) prior, home-country work experience. These factors are not mutually exclusive but interplay to assist highly skilled migrant women in obtaining employment in Australia. These findings have contributed to the migrant employment literature in filling an empirical gap and supporting human capital theory, as well as presenting micro, meso, and macro implications for policy.
Literary Neuroexistentialism: Coming to Terms with Materialism and Finding Meaning in the Age of Neuroscience through Literature
Authors: Høeg Mette Leonard 
Published: May 2024

AbstractWith the rise of the scientific authority of neuroscience and recent neurotechnological advances, the understanding of the human being and its future is beginning to undergo a radical change. As a result, a normative and existential vacuum is opening and hopes as well as fears about the future are flourishing. Some philosophers are anticipating a broad neuroscientific disenchantment, sociocultural disruption and a new existential anxiety related to the clash of the neuroscientific and humanistic image of humans. Others are expecting the technological and scientific developments to lead to human enhancement and existential emancipation. In the first part of this commentary, I outline these two contrasting responses to the rise of neurocentricism and non-anthropocentrism. In the second part, I argue that the divide between the old anthropocentric paradigm and the emerging neuroscientific is misconceived and that literature and fictional narrative are particularly illustrative of the possibility of integrating scientific materialism with humanism. I use the contemporary literary-philosophical work The Creative Act by Rick Rubin to show that humanist ideas can indeed cohere with anti-essentialist and neuroscientific notions of personal identity and self and how existential meaning and comfort can be found in a neuroscientifically and deterministically explained world.
CR Compactification for Asymptotically Locally Complex Hyperbolic Almost Hermitian Manifolds
Authors: Pinoy Alan 
Published: May 2024

AbstractIn this article, we consider a complete, non-compact almost Hermitian manifold whose curvature is asymptotic to that of the complex hyperbolic space. Under natural geometric conditions, we show that such a manifold arises as the interior of a compact almost complex manifold whose boundary is a strictly pseudoconvex CR manifold. Moreover, the geometric structure of the boundary can be recovered by analysing the expansion of the metric near infinity.