bluuebunny/crossref_metadata_2025_split huggingface dataset:
Small‐size multiband planar antenna for LTE700/2300/2500 operation in the tablet computer
Authors: Wong Kin‐Lu , Lyu Chao‐An , Chou Liang‐Che 
Published: November 2011

AbstractA small‐size multiband planar antenna can be obtained using a long parasitic shorted strip and a monopole feed encircled by the same. Such a configuration can lead to a small antenna size for multiband operation, and a promising design with a small size of 12 × 35 mm2 for covering three‐band LTE700/2300/2500 operation (704–787/2300–2400/2500–2690 MHz bands) in the tablet computer is presented. The antenna is easy to fabricate on one surface of an FR4 substrate and is composed of an inverted‐L strip as the monopole feed and a long parasitic shorted strip encircling the inverted‐L monopole. The long shorted strip is parasitically excited to generate a 0.25‐wavelength resonant mode at about 750 MHz to cover the LTE700 operation, while the inverted‐L monopole generates a 0.25‐wavelength resonant mode at about 2.5 GHz to cover the LTE2300/2500 operation. Details of the proposed antenna are described. Radiation characteristics of the antenna and its body specific absorption rate results for tablet computer applications are also presented. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:81–86, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26507
WWAN/LTE printed slot antenna for tablet computer application
Authors: Wong Kin‐Lu , Lin Wun‐Jian 
Published: November 2011

AbstractA printed slot antenna comprising two quarter‐wavelength slots of different lengths and a half‐wavelength slot for eight‐band wireless wide area network/long term evolution operation in the tablet computer is presented. The two quarter‐wavelength slots are open slots or monopole slots, and the half‐wavelength slot is aligned in‐between the two quarter‐wavelength slots. The three slots are excited using a two‐strip feedline which is printed on the opposite surface of the printed slots. The proposed three‐slot configuration can lead to two wide operating bands, with the lower one covering the 704–960 MHz band and the upper one covering the 1710–2690 MHz band. Good radiation efficiency for frequencies over the operating bands is obtained. The simulated body specific absorption rate values of the antenna in the bottom face, landscape and portrait orientations to the flat phantom in the body specific absorption rate testing model also meet the limit of 1.6 W/kg for 1‐g tissue. Details of the results are presented. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:44–49, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26509
A compact dual bevel planar monopole antenna with lumped element for ultra high frequency/very high frequency application
Authors: Jusoh M. , Jamlos M. F. , Kamarudin M. R. 
Published: November 2011

AbstractA novel small size planar monopole antenna operating from 0.1 to 1100 MHz is proposed. A planar monopole antenna constructed with 148 mm × 64 mm of radiating element and 80 mm square of ground plane is suitable for cognitive radio (CR) applications where it can cover a very high frequency and a partial of ultra high frequency (UHF) band for spectrum sensing. The proposed monopole antenna is designed by combining a beveling technique and resistor lumped element loading by employing FR4 substrate for low‐cost intention. The integration of the resistor with double bevel contributes to the behavior of an inductor as more current are excited to the ground eventually making the radiating element becomes more magnetic. Furthermore, it is found that 50° of dual bevel angle give optimization results for the impedance bandwidth of the antenna. As a result, the low frequency has shifted to the left and enhanced the antenna's impedance bandwidth significantly from 2.2:1 (103%) to 11:1 (200%). The proposed antenna is also extensively proficient in producing divisive radiation patterns with vertical polarization at four different frequencies; 200, 500, 800, and 1000 MHz. The presented antenna performances clarify the potential of the approach between simulation and the measurement results. Instead of CR, the proposed antenna has attractive potentials to be used for GSM, broadcasting, UHF radio frequency identification (RFID) and radio astronomy applications in the future. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:156–160, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26515
Protective effect of scFv‐DAF fusion protein on the complement attack to acetylcholine receptor: A possible option for treatment of myasthenia gravis
Authors: Song Chen , Xu Zhikai , Miao Jianting , Xu Jiang , Wu Xingan , Zhang Fanglin , Lin Hong , Li Zhuyi , Kaminski Henry J. 
Published: November 2011

AbstractIntroduction: Autoantibody‐induced complement activation, which causes disruption of the postsynaptic membrane, is recognized as a key pathogenic factor in myasthenia gravis (MG). Therefore, specific targeting of complement inhibitors to the site of complement activation is a potential therapeutic strategy for treatment of MG. Methods: We assessed expression of single‐chain antibody fragment–decay accelerating factor (scFv‐DAF), comprising a single‐chain fragment scFv1956 based on the rat complement inhibitor DAF in prokaryotic systems, and studied its inhibitory effect on complement deposition in vitro. Results: The recombinant conjugate scFv‐DAF completely retained the wild‐type binding activity of scFv1956 to AChR and inhibited complement activation of DAF in vitro. Conclusions: We found that scFv‐DAF could bind specifically to TE671 cells, and it is significantly more potent at inhibiting complement deposition than the untargeted parent molecule DAF. scFv‐DAF may be a candidate for in vivo protection of the AChR in MG. Muscle Nerve, 2012
Sulfur‐36S stable isotope labeling of amino acids for quantification (SULAQ)
Authors: Jehmlich Nico , Kopinke Frank‐Dieter , Lenhard Steffi , Vogt Carsten , Herbst Florian‐Alexander , Seifert Jana , Lissner Ulrike , Völker Uwe , Schmidt Frank , von Bergen Martin 
Published: November 2011

AbstractWe introduce a universal metabolic labeling strategy using elemental heavy 36Sulfur (36S) called 36Sulfur stable isotope labeling of amino acids for quantification (SULAQ). In the proof of principle experiment, Pseudomonas putida KT2440 was grown in defined minimal medium with sodium benzoate or sodium succinate as the sole carbon and 32S‐ or 36S‐sodium sulfate as the sole sulfur sources. Quantification using mass spectrometry resulted in 562 proteins with 1991 unique peptides. SULAQ technology can be a valuable alternative strategy for the quantitative comparisons in MS‐based proteomics approaches characterizing bacterial and other biological samples in different growth conditions.
Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)
Authors: Wang Zhen , Hill Salisha , Luther James M. , Hachey David L. , Schey Kevin L. 
Published: November 2011

AbstractExosomes are membrane vesicles that are secreted by cells upon fusion of multivesicular bodies with the plasma membrane. Exosomal proteomics has emerged as a powerful approach to understand the molecular composition of exosomes and has potential to accelerate biomarker discovery. Different proteomic analysis methods have been previously employed to establish several exosome protein databases. In this study, TFE solution‐phase digestion was compared with in‐gel digestion and found to yield similar results. Proteomic analysis of urinary exosomes was performed by multidimensional protein identification technology (MudPIT) after TFE digestion. Nearly, 3280 proteins were identified from nine human urine samples with 31% overlap among nine samples. Gene ontology (GO) analysis, coupled with detection of all of the members of ESCRT machinery complex, supports the multivesicular origin of these particles. These results significantly expand the existing database of urinary exosome proteins. Our results also indicate that more than 1000 proteins can be detected from exosomes prepared from as little as 25 mL of urine. This study provides the largest set of proteins present in human urinary exosome proteomes, provides a valuable reference for future studies, and provides methods that can be applied to exosomal proteomic analysis from other tissue sources.
Concentration‐dependent oligomerization and oligomeric arrangement of LptA
Authors: Merten Jacqueline A. , Schultz Kathryn M. , Klug Candice S. 
Published: November 2011

AbstractGram‐negative bacteria such as Escherichia coli have an inner membrane and an asymmetric outer membrane (OM) that together protect the cytoplasm and act as a highly selective permeability barrier. Lipopolysaccharide (LPS) is the major component of the outer leaflet of the OM and is essential for the survival of nearly all Gram‐negative bacteria. Recent advances in understanding the proteins involved in the transport of LPS across the periplasm and into the outer leaflet of the OM include the identification of seven proteins suggested to comprise the LPS transport (Lpt) system. Crystal structures of the periplasmic Lpt protein LptA have recently been reported and show that LptA forms oligomers in either an end‐to‐end arrangement or a side‐by‐side dimer. It is not known if LptA oligomers bridge the periplasm to form a large, connected protein complex or if monomeric LptA acts as a periplasmic shuttle to transport LPS across the periplasm. Therefore, the studies presented here focus specifically on the LptA protein and its oligomeric arrangement and concentration dependence in solution using experimental data from several biophysical approaches, including laser light scattering, crosslinking, and double electron electron resonance spectroscopy. The results of these complementary techniques clearly show that LptA readily associates into stable, end‐to‐end, rod‐shaped oligomers even at relatively low local protein concentrations and that LptA forms a continuous array of higher order oligomeric end‐to‐end structures as a function of increasing protein concentration.
Asparagine and glutamine differ in their propensities to form specific side chain‐backbone hydrogen bonded motifs in proteins
Authors: Vasudev Prema G. , Banerjee Mousumi , Ramakrishnan C. , Balaram P. 
Published: November 2011

AbstractShort range side chain‐backbone hydrogen bonded motifs involving Asn and Gln residues have been identified from a data set of 1370 protein crystal structures (resolution ≤ 1.5 Å). Hydrogen bonds involving residues i − 5 to i + 5 have been considered. Out of 12,901 Asn residues, 3403 residues (26.4%) participate in such interactions, while out of 10,934 Gln residues, 1780 Gln residues (16.3%) are involved in these motifs. Hydrogen bonded ring sizes (Cn, where n is the number of atoms involved), directionality and internal torsion angles are used to classify motifs. The occurrence of the various motifs in the contexts of protein structure is illustrated. Distinct differences are established between the nature of motifs formed by Asn and Gln residues. For Asn, the most highly populated motifs are the C10 (COδi …NHi + 2), C13 (COδi …NHi + 3) and C17 (NδHi …COi − 4) structures. In contrast, Gln predominantly forms C16 (COεi …NHi − 3), C12 (NεHi …COi − 2), C15 (NεHi …COi − 3) and C18 (NεHi …COi − 4) motifs, with only the C18motif being analogous to the Asn C17structure. Specific conformational types are established for the Asn containing motifs, which mimic backbone β‐turns and α‐turns. Histidine residues are shown to serve as a mimic for Asn residues in side chain‐backbone hydrogen bonded ring motifs. Illustrative examples from protein structures are considered. Proteins 2012; © 2011 Wiley Periodicals, Inc.
The effect of observed vertical structure, habits, and size distributions on the solar radiative properties and cloud evolution of cirrus clouds
Authors: Yang Huiyi , Dobbie Steven , Herbert Ross , Connolly Paul , Gallagher Martin , Ghosh Sat , Al‐Jumur Sardar M. R. K. , Clayton James 
Published: November 2011

AbstractCirrus observations taken during EMERALD1 clearly showed vertical structure in ice crystal habit and size distribution. In this study, we use these observations along with radiative and cloud modelling to assess the importance of this observed vertical structure in size and habit on radiative properties and cloud evolution. We show that neglecting the vertical structure results in changes to the solar upwelling and downwelling fluxes of 10 and 8 W m−2, respectively. If further simplifications are made and aggregate and rosettes are treated more simplistically (as columns) then the upwelling and downwelling fluxes are altered by about 12 and 16 W m−2, respectively. [Correction added 8 May 2012 after original online publication: the end of the preceding sentence has been changed from ‘16 and 12 W m−2, respectively’.] It was noted that the effects of simplifying the vertical structure and habits act in competing ways in terms of the fluxes and therefore emphasize the need to consider both effects in order to improve modelling rather than considering either in isolation.Often, general circulation models have highly parametrized treatments of cloud properties. We illustrate that crude assumptions about ice crystal effective sizes used in models (from the literature) can result in fluxes being in error by 100 W m−2 or more compared to using the observations. The above results are contrasted with effects of ice crystal roughness (altering the asymmetry). We show that moderate estimates of roughness lead to changes in the upward and downward fluxes of about 10–15 W m−2. This shows that vertical structure, habits and knowledge of size distribution are key factors and on a par with such effects as ice particle roughness, which is considered to have a highly uncertain but important cirrus radiative effect. Copyright © 2011 Royal Meteorological Society
Application of Multivariate Analysis in Mid‐Infrared Spectroscopy as a Tool for the Evaluation of Waste Frying Oil Blends
Authors: Hocevar Luciano , Soares Vitória R. B. , Oliveira Fábio S. , Korn Maria Graças A. , Teixeira Leonardo S. G. 
Published: November 2011

AbstractMid‐infrared spectroscopy, in association with multivariate chemometric techniques, was employed for pattern recognition and the determination of the composition of waste frying oils (WFO); data are presented in terms of the percentage of soybean oil, palm oil and hydrogenated vegetable fat in frying oil blends. Principal component analysis (PCA) was performed using spectral data (3,000–600 cm−1) to discriminate between the samples containing 100% soybean oil, 100% palm oil, 100% hydrogenated vegetable fat groups and their blends. Additionally, the results indicated that partial least squares (PLS) models based on mid‐infrared spectra were suitable as practical analytical methods for predicting the oil contents in WFO blends. PLS models were validated by a representative prediction set, and the root mean square errors of prediction (RMSEP) were 2.8, 4.7 and 5.5% for palm oil, soybean oil and hydrogenated vegetable fat, respectively. The proposed methodology can be very useful for the rapid and low cost determination of waste frying oil composition while also aiding in decisions regarding the management of oil pretreatment and production routes for biodiesel production.
Migration, Marital Change, and HIV Infection in Malawi
Authors: Anglewicz Philip 
Published: November 2011

Abstract
Research on the relationship between migration and HIV infection in sub-Saharan Africa often suggests that migrants are at higher risk of HIV infection because they are more likely to engage in HIV risk behaviors than nonmigrants, and they tend to move to areas with a relatively higher HIV prevalence. Although migration may be a risk factor for HIV infection, I instead focus on the possibility that the HIV positive are more likely to migrate. Using a longitudinal data set of permanent rural residents and migrants from Malawi, I find that migrants originating from rural areas are indeed more likely than nonmigrants to be HIV positive and to have engaged in HIV risk behaviors. The increased HIV risk among migrants may be due to the selection of HIV-positive individuals into migration; I find that HIV-positive individuals are more likely to migrate than those who are HIV negative. The explanation for this phenomenon appears to be marital instability, which occurs more frequently among HIV-positive individuals and leads to migration after marital change.
The relationship of resting cerebral blood flow and brain activation during a social cognition task in adolescents with chronic moderate to severe traumatic brain injury: a preliminary investigation
Authors: Newsome Mary R. , Scheibel Randall S. , Chu Zili , Hunter Jill V. , Li Xiaoqi , Wilde Elisabeth A. , Lu Hanzhang , Wang Zhiyue J. , Lin Xiaodi , Steinberg Joel L. , Vasquez Ana C. , Cook Lori , Levin Harvey S. 
Published: November 2011

AbstractAlterations in cerebrovascular function are evident acutely in moderate to severe traumatic brain injury (TBI), although less is known about their chronic effects. Adolescent and adult patients with moderate to severe TBI have been reported to demonstrate diffuse activation throughout the brain during functional magnetic resonance imaging (fMRI). Because fMRI is a measure related to blood flow, it is possible that any deficits in blood flow may alter activation. An arterial spin labeling (ASL) perfusion sequence was performed on seven adolescents with chronic moderate to severe TBI and seven typically developing (TD) adolescents during the same session in which they had performed a social cognition task during fMRI. In the TD group, prefrontal CBF was positively related to prefrontal activation and negatively related to non‐prefrontal, posterior, brain activation. This relationship was not seen in the TBI group, who demonstrated a greater positive relationship between prefrontal CBF and non‐prefrontal activation than the TD group. An analysis of CBF data independent of fMRI showed reduced CBF in the right non‐prefrontal region (p < .055) in the TBI group. To understand any role reduced CBF may play in diffuse extra‐activation, we then related the right non‐prefrontal CBF to activation. CBF in the right non‐prefrontal region in the TD group was positively associated with prefrontal activation, suggesting an interactive role of non‐prefrontal and prefrontal blood flow throughout the right hemisphere in healthy brains. However, the TBI group demonstrated a positive association with activation constrained to the right non‐prefrontal region. These data suggest a relationship between impaired non‐prefrontal CBF and the presence of non‐prefrontal extra‐activation, where the region with more limited blood flow is associated with activation limited to that region. In a secondary analysis, pathology associated with hyperintensities on T2‐weighted FLAIR imaging over the whole brain was related to whole brain activation, revealing a negative relationship between lesion volume and frontal activation, and a positive relationship between lesion volume and posterior activation. These preliminary data, albeit collected with small sample sizes, suggest that reduced non‐prefrontal CBF, and possibly pathological tissue associated with T2‐hyperintensities, may provide contributions to the diffuse, primarily posterior extra‐activation observed in adolescents following moderate to severe TBI.
Prevalence of and Factors Associated With Posterior Tibial Tendon Pathology on Sonographic Assessment
Authors: Jain Nitin B. , Omar Imran , Kelikian Armen S. , van Holsbeeck Lodewijk , Grant Thomas H. 
Published: November 2011

ObjectiveTo assess the frequency of and factors associated with supramalleolar posterior tibial tendon (PTT) pathology that often may be missed on sonography because of the limited field of view of ultrasound.DesignRetrospective cross‐sectional study.SettingLarge academic center.PatientsPatients with medial ankle pain and tenderness and with normal radiographs who presented for sonographic assessment (n = 217).MethodsTwo experienced musculoskeletal radiologists interpreted the studies by consensus.Main Outcome MeasurementPTT pathology.ResultsOf the 217 patients, 33.2% had grade 1 PTT pathology (n = 72), 14.3% had grade 2 pathology (n = 31), and 2.8% had grade 3 pathology (n = 6). When stratified by location, 29.0% of patients (n = 63) had inframalleolar abnormalities, 11.5% had retromalleolar pathology (n = 25), and 11 patients had supramalleolar pathology (5.1%). Four patients had PTT subluxation or dislocation. Age was significantly associated with PTT pathology (P = .02). A higher proportion of patients with supramalleolar (81.8%) and retromalleolar (72.0%) PTT pathology were women compared with patients who had inframalleolar (57.1%) PTT pathology. A higher proportion of patients with supramalleolar and retromalleolar PTT pathology had grade 2 tears compared with those with inframalleolar PTT pathology (36.4% for supramalleolar, 44.0% for retromalleolar, and 22.2% for inframalleolar pathology).ConclusionsWe present one of the largest studies on PTT pathology. PTT pathology can occur in the supramalleolar area, a region that often is not assessed on imaging. Although data are unavailable with regard to whether the natural history of supramalleolar PTT is different from that of other regions, patients with supramalleolar PTT pathology had more severe grades of tear and increased prevalence of tenosynovitis and were more often women. It is essential to recognize supramalleolar PTT pathology so that consequences of nontreatment such as medial arch collapse can be prevented.
An open trial of aripiprazole for the treatment of delirium in hospitalized cancer patients
Authors: Boettger Soenke , Breitbart William 
Published: November 2011

AbstractObjective:The purpose of this study was to examine the efficacy and safety of aripiprazole in the treatment of delirium in hospitalized cancer patients, and to examine differential responses based on delirium subtypes.Method:We conducted an analysis of 21 hospitalized cancer patients at Memorial Sloan-Kettering Cancer Center (MSKCC) who had been evaluated and treated for delirium with aripiprazole, using an MSKCC Institutional Review Board (IRB) approved Clinical Delirium Database. Measures used were the Memorial Delirium Assessment Scale (MDAS), the Karnofsky Scale of Performance Status (KPS), and side effect rating at baseline (T1), 2–3 days (T2), and 4–7 days (T3). All measurements were integrated into the routine clinical care of patients. Doses of aripiprazole were adjusted based on clinical response.Results:Patients treated for delirium with aripiprazole experienced significant improvement and resolution of delirium, with MDAS scores declining from a mean of 18.0 at baseline (T1) to mean of 10.8 at T2 and a mean of 8.3 at T3. KPS scores improved from 28.1 at baseline (T1) to 35.2 at T2 and 41 at T3. Delirium resolved (based on MDAS < 10) in 52.4% of cases at T2 and in 76.2% at T3. The mean dosage of aripiprazole required was 18.3 mg (range of 5–30) daily at T3. In our cohort of patients with hypoactive delirium, we observed a delirium resolution rate of 100% compared to the cohort of patients with hyperactive delirium (58.3% rate of delirium resolution). MDAS scores improved from 15.6 at T1 to 5.7 at T3 in hypoactive delirium and from 19.9 at T1 to 10.2 at T3 in hyperactive delirium. In patients with pre-morbid cognitive deficits and the hyperactive subtype of delirium, we observed a more limited treatment response to aripiprazole treatment for delirium. There were no clinically significant side effects noted.Significance of results:Aripiprazole is effective and safe in the treatment of delirium in hospitalized cancer patients. These preliminary finding suggest that aripiprazole may be most effective in resolving delirium of the hypoactive subtype.