bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Cardiopulmonary Bypass on Annexin A1 Expression in Peripheral Blood Mononuclear Cells of Children with Congenital Heart Disease
Authors: Zhou Gengxu , Hong Xiaoyang , Liu Yuhang , Feng Zhichun 
Published: April 2012

Effect of Cardiopulmonary Bypass on Annexin A1 Expression in Peripheral Blood Mononuclear Cells of Children with Congenital Heart DiseaseThis study aimed to investigate the effect of cardiopulmonary bypass (CPB) on Annexin A1 expression in the peripheral blood mononuclear cells (PBMCs) of children with congenital heart disease (CHD). A total of 30 children receiving CPB for interventricular septal defect were included. Peripheral blood was collected before and after CPB. PBMCs were collected by density gradient centrifugation. Protein extraction was performed by lysis and subjected to 2D-QUANT for protein quantitation. Isoelectric focusing electrophoresis (IEF) was carried out followed by gel image analysis. Protein spots with a difference in expression of >1.5 fold were collected as candidate proteins which were subjected to mass spectrometry for the identification of differentially expressed proteins. Western blot assay was employed to confirm the expressions of target proteins. Peripheral blood collected at two time points was subjected to two-dimensional electrophoresis, and a total of 12 differentially expressed proteins were identified. Of them, 5 proteins had decreased expression before CPB (T0) but their expressions increased after CPB (T1); the remaining 7 proteins had increased expressions before CPB but their expressions reduced after CPB. One of these differentially expressed proteins was Annexin A1. Western blot assay confirmed that Annexin A1 expression began to increase at 0.5 h after CPB, and the increase of Annexin A1 was more obvious after CPB. Our findings primarily indicate the potential mechanism underlying the role of PBMC in inflammatory response following CPB, and provide a target for the prevention and control of post-CPB systemic inflammatory response syndrome (SIRS).
Seltenes und zerstreutes Vorkommen: Auswirkungen auf den Paarungserfolg des Speierlings
Authors: Kamm Urs , Gugerli Felix , Rotach Peter , Edwards Peter , Holderegger Rolf 
Published: April 2012

Rare and scattered: consequences for the mating success of the service tree
Using a population genetic approach, we studied the effect of the highly scattered occurrence of the rare service tree (Sorbus domestica) in the canton of Schaffhausen (Switzerland) on the realised mating system. Therefore, we mapped all tree individuals in our extended study area and genotyped all 189 trees using microsatellites. Additionally, we genotyped 1183 seeds from 49 different mother trees and assigned the corresponding pollen-donor (father tree). We showed that effective pollinations occur over large spatial distances (&gt;16 km). Because the amount of effectively dispersed pollen decreased with increasing distance from its source, the spatial position of a tree in relation to its conspecific neighbours has a significant impact on the genetic composition of its offspring (seeds) — the more isolated a tree was, the higher was the proportion of self-fertilised offspring. Based on these results, we discuss management strategies aimed at securing the survival and increasing the fecundity, in particular flowering, of adult trees in the study area. If priorities have to be set, trees belonging to denser local groups of service trees should be favoured as they have a higher potential to produce genetically diverse offspring. These progenies can be used to produce high-quality planting material for artificial regeneration, a conservation measure which we consider necessary since we observed no natural regeneration from seeds in the study area. Stands may be managed in a silvicultural practice similar to that of coppice-with-standards. Promoting the regeneration of light-demanding and rare forest tree species, like service tree, wild service tree, wild pear and wild apple, may allow them grow to mature trees of high value, both ecologically and economically.
Microsatellite development for an endangered riparian inhabitant, Lilaeopsis schaffneriana subsp. recurva (Apiaceae)
Authors: Tew Jessica M. , Lance Stacey L. , Jones Kenneth L. , Fehlberg Shannon D. 
Published: April 2012

• Premise of the study: Microsatellite markers were developed and characterized to evaluate genetic diversity and population structure in Lilaeopsis schaffneriana subsp. recurva, an endangered species endemic to wetlands dispersed throughout southeastern Arizona, USA, and northern Sonora, Mexico.• Methods and Results: Eight loci (one of which was monomorphic) were developed and characterized in 48 individuals from two populations. The total number of alleles was 35, ranging from one to 10 per locus. Many of the primers amplified in L. carolinensis, L. chinensis, L. masonii, L. occidentalis, L. schaffneriana subsp. schaffneriana, Oxypolis fendleri, and Eryngium lemmonii.• Conclusions: Development of these novel microsatellite loci will facilitate a deeper understanding of genetic diversity, mode of reproduction, and population structure not only in L. schaffneriana subsp. recurva, but also in apiaceous relatives.
Le rôle des communautés de pratique dans le développement de l’ambidextrie contextuelle : le cas GDF SUEZ
Authors: Dupouët Olivier , Barlatier Pierre-Jean 
Published: April 2012

Cette contribution propose de voir les communautés de pratique pilotées comme un support à l’ambidextrie contextuelle. En présentant la capacité de ces structures à supporter des activités d’exploration et d’exploitation, nous montrons qu’elles satisfont aux hypothèses de l’ambidextrie contextuelle. Nous développons cette proposition à travers l’étude du réseau de communautés du groupe GDF SUEZ. Cette étude permet d’affiner notre compréhension des principaux aspects de l’ambidextrie contextuelle : un contexte favorisant tant la performance que le partage de connaissances, la gestion des tensions entre exploration et exploitation au niveau individuel et la capacité à combiner alignement et flexibilité sur l’ensemble d’une organisation.
Le critique et la scène
Authors: Pefanis Georges P. 
Published: April 2012

La critique de théâtre aujourd’hui pourrait être convertie à un discours polyvalent qui questionne les événements théâtraux en tirant des expériences, des significations et formes mentales des champs cognitifs adjacents. L’élargissement du canon théâtral, sa réadaptation aux nouvelles données culturelles, la reconstitution de la forme théâtrale à l’aide de matériaux hybrides et la décentralisation plurielle de l’acte de représentation, ainsi que l’autonomisation des arts dans les processus scéniques sont quelques uns des facteurs les plus importants qui différencient en grande partie, non seulement les représentations elles-mêmes, mais également la perception qu’en a le spectateur spécialiste.
La critique de théâtre en Grèce contemporaine à certains égards était, jusqu’ à très récemment, peu étudiée aux universités comme aux cercles des intellectuels. Ce fut la raison pour laquelle elle peut se caractériser, soit enfermée dans de vieilles postures acquises par le passé, de manière empirique et inconstante, sinon arbitraire, soit amenée à un relativisme sans issue, en suivant les différentes tendances importées. L’ interpénétration de la déontologie scientifique et de l’actualité au sein de la critique théâtrale peut considérablement améliorer la situation dans le domaine de la perception des représentations et progressivement lever l’opposition stérile qui parfois se manifeste entre la science, la méditation et la création artistique.
Dialectique de l’intérieur et de l’extérieur dans trois événements in situ présentés dans l’édition 2010 du FTA
Authors: Siaud Florent 
Published: April 2012

Né d’une volonté d’extraire l’oeuvre d’art de ses habituels lieux de présentation pour les inscrire dans des contextes insolites, le théâtre in situ délaisse les espaces sanctuarisés de la création. Comme l’ont montré trois spectacles présentés dans l’édition 2010 du Festival TransAmérique de Montréal, il permet au spectateur de vivre une expérience artistique au coeur de la ville. Enquête anthropologique sur ce qui fonde nos rites, notre inconscient collectif et nos sentiments d’appartenance, le théâtre in situ n’est pourtant pas exclusivement une manifestation à ciel ouvert : bouleversement de l’espace urbain, il occasionne parallèlement une plongée en soi qui conduit le sujet à s’interroger sur son rapport à sa propre mémoire ou à son activité sensorielle de citadin.
Adaptive control of the oxidation ditch reactors in a wastewater treatment plant
Authors: Kandare Gregor , Viúdez‐Moreiras Daniel , Hernández‐del‐Olmo Félix 
Published: April 2012

SUMMARYThis paper describes the application of adaptive predictive expert (ADEX) control methodology to the oxidation ditch reactor in the wastewater treatment plant of Ceutí (Murcia, Spain) and evaluates the performance of the ADEX control system against that of the previous control system operating the plant. After a basic description of ADEX control methodology, the ditch reactor is described, as well as the control objectives and the control strategy, which focused on energy consumption reduction. The results of the application of the ADEX control system show significant improvement compared with the previous control system in terms of higher stability and precision of controlled variables, reduction of energy consumption of the plant, and better quality of the effluent water. Copyright © 2012 John Wiley & Sons, Ltd.
Type II enteropathy‐associated T‐cell lymphoma: A multicenter analysis from the Asia Lymphoma Study Group
Authors: Tse Eric , Gill Harinder , Loong Florence , Kim Seok Jin , Ng Siok‐Bian , Tang Tiffany , Ko Young‐Hyeh , Chng Wee‐Joo , Lim Soon‐Thye , Kim Won Seog , Kwong Yok‐Lam 
Published: April 2012

AbstractEnteropathy‐associated T‐cell lymphoma (EATL) is a rare primary gastrointestinal T‐cell lymphoma. A multicenter study from the Asia Lymphoma Study Group identified 38 EATL patients within a 19‐year period. All cases were type II EATL. Men were affected twice as common as women, at a median age of 59 (23–89) years. None had a history of celiac disease. The sites of involvement were small bowel and stomach (5%), small bowel (63%), small and large bowel (16%), and large bowel (18%). Common presenting features were bowel perforation (34%), pain (32%), and obstruction (21%). Lymphomas showed monomorphic neoplastic lymphoid infiltrates that were CD3+ (100%), CD56+ (91%), TIA‐1+ (96%), CD4–CD8+ (63%), CD4+CD8+ (19%), CD4–CD8– (16%), and CD4+CD8– (3%). Epstein Barr virus was demonstrable in three cases. Despite chemotherapy and/or surgical resection, the overall response and complete response rates were poor at 46% and 38%. The median overall survival (OS) was 7 months and progression‐free‐survival (PFS) 1 month. Five patients underwent hematopoietic stem cell transplantation all were alive. Age and the prognostic index for peripheral T‐cell lymphoma were not prognostically significant. Good performance status was associated with better OS (P = 0.03), and response to initial treatment led to better OS and PFS (P < 0.001). Am. J. Hematol. 87:663–668, 2012. © 2012 Wiley Periodicals, Inc.
Risk factors associated with asthma phenotypes in dental healthcare workers
Authors: Singh Tanusha , Bello Braimoh , Jeebhay Mohamed F. 
Published: April 2012

AbstractBackgroundExposure in the dental environment can increase the risk of respiratory disease in dental healthcare workers (HCWs). This study investigated the prevalence of asthma phenotypes in dental HCWs and associated risk factors.MethodsA cross‐sectional study of 454 dental HCWs in five dental institutions in South Africa was conducted. A self‐administered questionnaire elicited the health and employment history of subjects. Sera was analyzed for atopic status and latex sensitization. Pre‐ and post‐bronchodilator spirometry was performed.ResultsThe prevalence of atopic asthma was 6.9%, non‐atopic asthma 5.9% and work‐exacerbated asthma (WEA) 4.0%. Atopy and work‐related ocular‐nasal symptoms were strong predictors of WEA (OR: 3.4; 95% CI: 1.07–10.8; OR: 6.7, 95% CI: 2.4–19.1), respectively. Regular use of personal protective equipment (PPE) was associated with a protective affect (OR: 0.23, 95% CI: 0.1–0.7) among non‐atopic asthmatics, while glove use and respiratory protection was protective among atopic asthmatics (OR: 0.39, 95% CI: 0.17–0.89).ConclusionIdentification of risk factors associated with specific asthma phenotypes in dental HCWs can be used to focus preventive strategies for asthmatics. Am. J. Ind. Med. 56:90–99, 2013. © 2012 Wiley Periodicals, Inc.
States with low non‐fatal injury rates have high fatality rates and vice‐versa
Authors: Mendeloff John , Burns Rachel 
Published: April 2012

AbstractBackgroundState‐level injury rates or fatality rates are sometimes used in studies of the impact of various safety programs or other state policies. How much does the metric used affect the view of relative occupational risks among U.S. states? This paper uses a measure of severe injuries (fatalities) and of less severe injuries (non‐fatal injuries with days away from work, restricted work, or job transfer–DART) to examine that issue.MethodsWe looked at the correlation between the average DART injury rate (from the BLS Survey of Occupational Injuries and Illnesses) and an adjusted average fatality rate (from the BLS Census of Fatal Occupational Injuries) in the construction sector for states for 2003–2005 and for 2006–2008. The RAND Human Subjects Protection Committee determined that this study was exempt from review.ResultsThe correlations between the fatal and non‐fatal injury rates were between −0.30 and −0.70 for all construction and for the subsector of special trade contractors. The negative correlation was much smaller between the rate of fatal falls from heights and the rate of non‐fatal falls from heights. Adjusting for differences in the industry composition of the construction sector across states had minor effects on these results.ConclusionAlthough some have suggested that fatal and non‐fatal injury rates should not necessarily be positively correlated, no one has suggested that the correlation is negative, which is what we find. We know that reported non‐fatal rates are influenced by workers' compensation benefits and other factors. Fatality rates appear to be a more valid measure of risk. Efforts to explain the variations that we find should be undertaken. Am. J. Ind. Med. 56:509–519, 2013. © 2012 Wiley Periodicals, Inc.
Synthesis and characterization of new cardo poly(ether imide)s derived from 9,9‐bis [4‐(4‐aminophenoxy)phenyl]xanthene
Authors: Sheng Shou‐Ri , Zhang Wei , Lu Chun , Wan Jiong , Liu Xiao‐Ling , Song Cai‐Sheng 
Published: April 2012

AbstractA series of new cardo poly(ether imide)s bearing flexible ether and bulky xanthene pendant groups was prepared from 9,9‐bis[4‐(4‐aminophenoxy)phenyl]xanthene with six commercially available aromatic tetracarboxylic dianhydrides in N,N‐dimethylacetamide (DMAc) via the poly(amic acid) precursors and subsequent thermal or chemical imidization. The intermediate poly(amic acid)s had inherent viscosities between 0.83 and 1.28 dL/g, could be cast from DMAc solutions and thermally converted into transparent, flexible, and tough poly(ether imide) films which were further characterized by X‐ray and mechanical analysis. All of the poly(ether imide)s were amorphous and their films exhibited tensile strengths of 89–108 MPa, elongations at break of 7–9%, and initial moduli of 2.12–2.65 GPa. Three poly(ether imide)s derived from 4,4′‐oxydiphthalic anhydride, 4,4′‐sulfonyldiphthalic anhydride, and 2,2‐bis(3,4‐dicarboxyphenyl))hexafluoropropane anhydride, respectively, exhibited excellent solubility in various solvents such as DMAc, N,N‐dimethylformamide, N‐methyl‐2‐pyrrolidinone, pyridine, and even in tetrahydrofuran at room temperature. The resulting poly(ether imide)s with glass transition temperatures between 286 and 335°C had initial decomposition temperatures above 500°C, 10% weight loss temperatures ranging from 551 to 575°C in nitrogen and 547 to 570°C in air, and char yields of 53–64% at 800°C in nitrogen. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Reaction kinetics studies on plasma‐treated polypropylene–polystyrene interfaces
Authors: Yan Da , Guo Chu , Xu Xinhua , Ma Guiqiu , Sheng Jing 
Published: April 2012

AbstractIn this article, the effects of low temperature Ar glow discharge plasma modification on the surface of polypropylene (PP) and polystyrene (PS) plates were characterized by X‐ray photoelectron spectroscopy, and the temporal change of the complex viscosity (η*) of PP/PS plates with a sandwich structure were measured by a rotational rheometer. The results showed that the formation of reactive groups on the surface of PP and PS plates was due to the reaction of O2 with some free radicals when exposed to air. In the rheology study, because of the increase of interfacial adhesion strength due to the coupling reaction between the reactive groups at the interface, η* increased with welding time. There were two distinct stages for the changes of η* with welding time. In Stage I, η* increased rapidly and indicated a reaction‐controlled kinetics, the apparent reaction kinetics was a first‐order reaction; in Stage II, η* increased slowly and indicated a diffusion‐controlled reaction. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Design and development of microparticulate delivery system of metronidazole: Experimental design methodology
Authors: Shukla Raj Kumar , Tiwari Akanksha 
Published: April 2012

AbstractThis study describes the application of response surface methodology in the optimization of guar gum microspheres for colon‐specific delivery of metronidazole. The effect of varying the relative percent of the four factors used, that is guar gum, glutaraldehyde, swelling time, and stirring speed, has been systematically investigated for identifying their best values to optimize the drug release and encapsulation efficiency as well as to highlight possible interactions among the components. Different batches were prepared according to 24 factorial designs and randomly evaluated for drug release and drug encapsulation efficiency. Analysis of response surface plots allowed identification of the best combination of four levels to minimize drug release in upper part of gastrointestinal tract and maximize the encapsulation efficiency. The scanning electron microscopy was used to characterize the surface of these microspheres. Drug polymer interactions were assessed by differential scanning calorimetry and XRD. The good correspondence between calculated and experimental values indicated in the validity of the generated statistical model. Only a small fraction of drug was released at acidic pH; however, the release of drug was found to be higher in the presence of rat cecal contents, indicating the susceptibility of crosslinked guar gum matrix to colonic enzymes released from rat cecal contents. Metronidazole release kinetics corresponds best to zero‐order model and drug release mechanism was diffusion and swelling controlled. The significance of differences was evaluated by analysis of variance (ANOVA). Differences were considered statistically significant at P < 0.05. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Mechanical and shape‐memory properties of polyamide/maleated polyethylene/linear low‐density polyethylene blend
Authors: Lin Guo‐Ming , Sui Guo‐Xin , Yang Rui 
Published: April 2012

AbstractNovel polymer blends of polyamide and linear low‐density polyethylene with maleated polyethylene as compatibilizers were prepared in a modular intermeshing corotating twin‐screw extruder. Polymer blends with different contents of polyamide in polyethylene matrix were obtained. The mechanical properties were studied in terms of the tensile strength and elongation‐to‐break. The shape‐memory properties of the blended materials were characterized using three‐point bending test in a temperature‐controlled chamber. The results show that the incorporation of maleated polyethylene has a strong effect on the tensile properties and the morphology of the blends. The shape‐memory effect of blended materials is affected by polyamide weight fraction, and 60 wt % polyethylene, 20 wt % polyamide, and 20% maleated polyethylene have an acceptable performance. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Polyester/cellulose acetate composites: Preparation, characterization and biocompatible
Authors: Wang Hui‐Min , Chou Yi‐Ting , Wu Chin‐San , Yeh Jen‐Taut 
Published: April 2012

AbstractThe biocompatibility, morphology, and mechanical thermal properties of composite materials composed of maleic anhydride‐grafted polylactide (PLA‐g‐MA) and cellulose acetate (CA) were evaluated. Composites containing maleic anhydride‐grafted PLA (PLA‐g‐MA/CA) exhibited noticeably superior mechanical properties due to greater compatibility between the two components. The dispersion of CA in the PLA‐g‐MA matrix was highly homogeneous as a result of ester formation, and the consequent creation of branched and cross‐linked macromolecules, between the carboxyl groups of PLA‐g‐MA and hydroxyl groups in CA. The human skin dermal fibroblasts (FBs) seeded on these two novel series membranes to verify the wound dressing characterization properties. With time‐dependent course, the FBs proliferation demonstrated a better increasing performance on the series membranes of PLA/CA than PLA‐g‐MA/CA. The immunofluorescent staining illustrated FBs with normal morphological features. The collagen amount from FBs on the PLA/CA series was 25% higher than that seeded on regular culture‐plates after 7 days incubation. With CA content from 0 to 20%, the collagen amount increased apparently and up to the position of CA20%. Otherwise, with PLA‐g‐MA membranes, the collagen amount showed moderate stimulations. The SEM image presented secreted collagen from FBs on the PLA/CA membrane, indicating the bio‐functional properties of these membranes. The above result analysis, this PLA‐g‐MA/CA composites has good mechanical properties and biocompatible, in the future when use adjusts the formula according to the functionality, may increase the product utility. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012