bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bottom‐bounce ray angle subspace detector in the shadow zone of deep water
Authors: Liu Jia‐peng , Sun Chao , Li Ming‐yang , Wang Xuan 
Published: May 2024

AbstractPassive source detection is a challenging problem in the shadow zone, where the sound is contributed primarily by bottom‐bounce rays. The conventional beamforming detector (CBFD), which utilises the sound energy from a single direction, suffers potential significant performance degradation in the multipath‐signal scenario. The matched field detector (MFD) offers optimal performance by exploiting full‐wave field characteristics but is limited due to its reliance on prior ocean environmental knowledge. The authors demonstrate that the incident sound on a near‐surface vertical line array in the shadow zone can be approximated as a coherent sum of two plane waves that share a symmetric arrival angle about the horizontal. This leads to the signal subspace depending only on the arrival angle, which the authors call the bottom‐bounce ray angle subspace (BRAS). With generalised likelihood ratio test theory, the authors further derive the BRAS detector (BRASD). It can utilise the full signal energy under the premise of weak environmental knowledge requirements and is generally superior to the CBFD. Simulation results in a typical deep‐water channel under different source‐position and array configuration conditions demonstrate the effectiveness of the BRASD and suggest that it can even offer a performance comparable to that of the MFD under specific conditions.
Cervical Diastematomyelia: A Case Presentation and Systematic Review
Authors: Zhang Jeff F. , Strelko Oleksandr , Komarov Oleksandr , Kuts-Karpenko Viktoriia , Forbes Jonathan A , Fedorko Ostap , Tomycz Luke D. 
Published: May 2024

AbstractDiastematomyelia is a rare congenital disorder characterized by the separation of the spinal cord by an osseocartilaginous or fibrous septum. While diastematomyelia has been reported to be more common in the thoracic and lumbar regions, the true incidence of cervical diastematomyelia is currently unknown. In this study, we conducted the most comprehensive systematic review to date of all other case reports of diastematomyelia to better characterize the incidence of cervical diastematomyelia and provide comprehensive statistics on the clinical characteristics of diastematomyelia generally. Ninety-one articles were included in our study, which comprised 252 males (27.9%) and 651 females (72.0%) (and one patient with unspecified gender). In 507 cases, the vertebral level of the diastematomyelia was described, and we recorded those levels as either cervical (n = 8, 1.6%), thoracic (n = 220, 43.4%), lumbar (n = 277, 54.6%), or sacral (n = 2, 0.4%). In 719 cases, the type of diastematomyelia was specified as either Type I (n = 482, 67.0%) or Type II (n = 237, 33.0%). Our study found that diastematomyelia has been reported in the cervical region in only 1.6% of cases, and we provide comprehensive data that this disorder occurs in female-to-male ratio of approximately 2.6:1 and Type I versus Type II diastematomyelia in an estimated ratio of 2:1.
E-commerce and foreign direct investment: pioneering a new era of trade strategies
Authors: He Yugang 
Published: May 2024

AbstractThis study explores the dynamic interplay between foreign direct investment, e-commerce, and China’s export growth from 2005 to 2022 against the backdrop of the rapidly evolving global economy. Utilizing advanced analytical models that combine province- and year-fixed effects with fully modified ordinary least squares and dynamic ordinary least-squares methodologies, we delve into how foreign direct investment and e-commerce collectively boost China’s export capabilities. Our findings highlight a significant alignment between China’s export expansion and the global sustainable development agenda. We observe that China’s export growth transcends mere international investment and digital market engagement, incorporating sustainable practices such as effective utilization of local labor resources and an emphasis on technological advancements. This study also uncovers how knowledge capital and educational attainment positively impact export figures. A notable regional disparity is observed, with the eastern regions of China being more responsive to foreign direct investment and e-commerce influences on export trade compared to their western counterparts. This disparity underscores the need for region-specific policy approaches and sustainable strategies to evenly distribute the benefits of foreign direct investment and e-commerce. The study concludes that while foreign direct investment and e-commerce are crucial for China’s export growth, the underlying theme is sustainable development, with technological innovation and human capital being key to ongoing export success. The findings advocate for policies that balance economic drivers with sustainable development goals, ensuring both economic prosperity and environmental sustainability.
The origin of betaine in mouse oocytes and preimplantation embryos
Authors: McIntosh Emily R , McClatchie Taylor , Lee Martin , Zeisel Steven H , Jurisicova Andrea , Baltz Jay M 
Published: May 2024

Abstract
Betaine has important roles in preimplantation mouse embryos, including as an organic osmolyte that functions in cell volume regulation in the early preimplantation stages and as a donor to the methyl pool in blastocysts. The origin of betaine in oocytes and embryos was largely unknown. Here, we found that betaine was present from the earliest stage of growing oocytes. Neither growing oocytes nor early preantral follicles could take up betaine, but antral follicles were able to transport betaine and supply the enclosed oocyte. Betaine is synthesized by choline dehydrogenase, and female mice lacking Chdh did not have detectable betaine in their oocytes or early embryos. Supplementing betaine in their drinking water restored betaine in the oocyte only when supplied during the final stages of antral follicle development but not earlier in folliculogenesis. Together with the transport results, this implies that betaine can only be exogenously supplied during the final stages of oocyte growth. Previous work showed that the amount of betaine in the oocyte increases sharply during meiotic maturation due to upregulated activity of choline dehydrogenase within the oocyte. This betaine present in mature eggs was retained after fertilization until the morula stage. There was no apparent role for betaine uptake via the SIT1 (SLC6A20) betaine transporter that is active at the 1- and 2-cell stages. Instead, betaine was apparently retained because its major route of efflux, the volume-sensitive organic osmolyte – anion channel, remained inactive, even though it is expressed and capable of being activated by a cell volume increase.
Aberrant connectivity in the hippocampus, bilateral insula and temporal poles precedes treatment resistance in first-episode psychosis: a prospective resting-state functional magnetic resonance imaging study with connectivity concordance mapping
Authors: Skouras Stavros , Kleinert Maria-Lisa , Lee Edwin H M , Hui Christy L M , Suen Yi Nam , Camchong Jazmin , Chong Catherine S Y , Chang Wing Chung , Chan Sherry K W , Lo William T L , Lim Kelvin O , Chen Eric Y H 
Published: May 2024

Abstract
Functional connectivity resting-state functional magnetic resonance imaging has been proposed to predict antipsychotic treatment response in schizophrenia. However, only a few prospective studies have examined baseline resting-state functional magnetic resonance imaging data in drug-naïve first-episode schizophrenia patients with regard to subsequent treatment response. Data-driven approaches to conceptualize and measure functional connectivity patterns vary broadly, and model-free, voxel-wise, whole-brain analysis techniques are scarce. Here, we apply such a method, called connectivity concordance mapping to resting-state functional magnetic resonance imaging data acquired from an Asian sample (n = 60) with first-episode psychosis, prior to pharmaceutical treatment. Using a longitudinal design, 12 months after the resting-state functional magnetic resonance imaging, we measured and classified patients into two groups based on psychometric testing: treatment responsive and treatment resistant. Next, we compared the two groups’ connectivity concordance maps that were derived from the resting-state functional magnetic resonance imaging data at baseline. We have identified consistently higher functional connectivity in the treatment-resistant group in a network including the left hippocampus, bilateral insula and temporal poles. These data-driven novel findings can help researchers to consider new regions of interest and facilitate biomarker development in order to identify treatment-resistant schizophrenia patients early, in advance of treatment and at the time of their first psychotic episode.
Investigation of performance and emission characteristics using ethanol-blended gasoline fuel as a flex-fuel in two-wheeler vehicle mounted on a chassis dynamometer
Authors: Gupta Sourabh , Kanchan Sumit , Kaur Rupinder , Sandhu Sarbjot Singh 
Published: May 2024

Abstract
This study investigated the performance and emissions of flex fuels in a 110-cc BS6-compliant fuel-injected two-wheeler without ethanol adaptation adjustments. The tests were carried out under controlled conditions on a chassis dynamometer at 1000, 2000 and 3000 r.p.m. using ethanol blends from 10% ethanol (E10) to 85% ethanol (E85). Parameters examined included brake power (BP) output, brake-specific fuel consumption (BSFC), peak in-cylinder pressure and exhaust temperature. Emissions, including carbon monoxide (CO), hydrocarbons (HC), nitrogen oxide (NOx) and unregulated emissions, were also assessed. As the percentages of the ethanol blend increased from E10 to E85, there was a noticeable improvement in power output. At 1000 r.p.m., the BP ranged from 2.4 to 4.6 kW for different blends. The BSFC and the peak in-cylinder pressure followed a similar pattern, indicating enhanced performance and fuel efficiency with higher ethanol concentrations. Interestingly, using E85 at 1000 r.p.m. resulted in a significant 41.08% reduction in exhaust temperature compared with E10, although this difference decreased with higher blend percentages. Furthermore, replacing E10 with E85 at 1000 r.p.m. reduced CO and HC emissions by 9.17% and 38.34%, respectively. In contrast, NOx emissions increased at all r.p.m. levels with higher-ethanol blends, peaking at a 415 parts per million increase at 3000 r.p.m. However, unregulated emissions decreased significantly with increased r.p.m. and ethanol content. In summary, the use of flex-fuel blends in a two-wheeler resulted in a modest increase in BP output, improved fuel efficiency and lower CO and HC emissions. These findings are vital for optimizing ethanol blend utilization in two-wheeler engines under low-load conditions, considering both performance and environmental aspects.
Graphene oxide–lithium-ion batteries: inauguration of an era in energy storage technology
Authors: Mishra Yachana , Chattaraj Aditi , Aljabali Alaa AA , El-Tanani Mohamed , Tambuwala Murtaza M , Mishra Vijay 
Published: May 2024

Abstract
A significant driving force behind the brisk research on rechargeable batteries, particularly lithium-ion batteries (LiBs) in high-performance applications, is the development of portable devices and electric vehicles. Carbon-based materials, which have finite specific capacity, make up the anodes of LiBs. Many attempts are being made to produce novel nanostructured composite anode materials for LiBs that display cycle stability that is superior to that of graphite using graphene oxide. Therefore, using significant amounts of waste graphene oxide from used LiBs represents a fantastic opportunity to engage in waste management and circular economy. This review outlines recent studies, developments and the current advancement of graphene oxide-based LiBs, including preparation of graphene oxide and utilization in LiBs, particularly from the perspective of energy storage technology, which has drawn more and more attention to creating high-performance electrode systems.
Wind energy feasibility and wind turbine selection studies for the city Surat, India
Authors: P S Arshi Banu , Bhadani Maanat 
Published: May 2024

Abstract
Wind energy represents a clean, abundant and cost-effective power source, fostering job growth and environmental mitigation. Although wind energy harnesses several gigawatts today, its availability hinges on diverse factors, with geographical location standing out. Commercial turbines, with varying capacity ranges, saturate the market. Locating site-specific suitability and matching the appropriate turbine to meet specific requirements are of paramount importance. This study aims to assess the feasibility of wind energy in Surat, Gujarat, India and select an optimal small commercial turbine for residential use. The research involves Rayleigh and Weibull probability distribution functions based on yearlong velocity data. These distributions are fitted with actual data, revealing the most probable velocity (vmf = 3 m/s) and velocity at maximum power (vpmax = 5 m/s). The power availability of the site has been assessed as 42.6 W/m2 using both graphical and analytical methods. Several commercial turbines have been shortlisted based on on-site power criteria and their specifications are evaluated against site power availability. A comparative analysis culminates in identifying the most suitable turbine for the location. The best suitable turbine for the site with an annual energy yield of 8 MW has been suggested amongst selected turbines for small-scale residential applications.
Building a resilient future: collaborative sustainability regulation
Authors: Job Jovita Shanta , Khanna Shivi 
Published: May 2024

Abstract
The challenge of sustainability lies in achieving a balance between satisfying present needs and protecting resources for future generations with an emphasis on its three pillars—environmental, social and governance. This study explored sustainable development encompassing environmental, social and governance aspects along with sustainability reporting through various sustainability frameworks. A systematic review of literature for the period 2010–23 on major worldwide sustainability frameworks was conducted, by offering insights into enhancing reporting mechanisms for a sustainable future. Secondary data related to sustainability reports were obtained from the Sustainability Accounting Standards Board and International Integrated Reporting Council, which helped in examining sector and year variations across countries. The results reflected that mandatory sustainability disclosures help to meet the United Nations Sustainable Development Goals and global sustainability frameworks help to set standards, disseminate information and promote transparency. Collaboration of investment, company action and sustainability organizations can lead to a sustainable global economy. The adoption of sustainability reporting can help organizations by fostering a proper understanding of sustainability practices, improving transparency and identifying potential business opportunities in sectors with lower sustainability. The paper provided insights into sustainability reporting published across various countries in both advanced as well as emerging and developing economies. The analysis showed which sectors and time periods have had the most sustainability reports and which areas needed to be targeted for action to advance sustainable development.
Synthesis of Magnetic Attapulgite Nanoparticles Via a Novel Surface Covalent Reaction Method and its Application in the Magnetic Solid Phase Extraction
Authors: Wu Shuaibin , Peng Xuejuan 
Published: May 2024

Abstract
In this study, the attapulgite nanoparticle was immobilized on the surface of magnetic nanoparticle Fe3O4 via a novel surface covalent reaction method for the magnetic solid phase extraction (MSPE) for the first time. The surface covalent reaction method has the advantages of controllable steps, and can make the magnetic attapulgite nanoparticle (MANP) have good homogeneity and high stability. Field emission scanning electron microscopy, equipped with an energy dispersive spectrometer, Nitrogen adsorption BET, X-ray diffraction and Fourier transform infrared spectroscopy were applied to characterize the prepared MANP, confirming that the attapulgite nanoparticle could be effectively immobilized on the surface of magnetic nanoparticle Fe3O4 via covalent reactions. Under optimal conditions of the MSPE experiment based on the MANP, the limits of detection were found to be 10 ng/mL for melamine and 3 ng/mL for cyromazine with a relative standard deviation &lt; 10% by a high-performance liquid chromatography system. Meanwhile, 0.1 mg/mL melamine in milk and 0.1 mg/mL cyromazine in cucumber can also be detected according to our MSPE procedure. More importantly, the MANP still has good magnetism and enrichment efficiency after several decades of use. These results showed that the MANP prepared by our method is a kind of promising material for the MSPE.
The efficacy and safety of rituximab with or without glucocorticoid in inducing remission of MCD with different clinical presentations in adults: a retrospective study
Authors: Sun Yujiao , Li Zhuo , Sun Jing , Zhang Shasha , Wang Rong , Chen Bing 
Published: May 2024

ABSTRACT

Background
To investigate the efficacy and safety of rituximab (RTX) with or without glucocorticoid (GC) in inducing remission of minimal change disease (MCD) in adults.

Methods
Twenty-one adult MCD patients were included in the study. The patients were assigned to the following three groups according to their background before RTX treatment: an RTX single drug direct induction treatment group (Group A; n = 9), a short-term, low-dose GC combined with RTX induction treatment group (Group B; n = 4), and a short-term, adequate-dose GC-induced remission and RTX maintenance treatment group (Group C; n = 8). The primary endpoints were the time to induction of remission and the rate of clinical remission at 12 months.

Results
All patients achieved clinical remission, with 19 (90.48%) achieving complete remission (CR), and the median remission time was 4 (2.5, 12) weeks. Eight (88.89%) patients in Group A achieved CR, and the median remission time was 3 (2.25, 14) weeks. In Group B, three (75.00%) patients achieved CR, with a median remission time of 4 (4, 10) weeks. In Group C, eight (100.00%) patients achieved CR, and the median remission time was 3.5 (2, 4) weeks.

Conclusions
In MCD patients without acute kidney injury, adequate RTX alone or short-term combined treatment with low-dose GCs can effectively induce and maintain MCD remission. Adequate short-term GCs combined with RTX maintenance may be an effective alternative for MCD patients in context of acute kidney injury. There is a need to investigate different induction therapy regimens for the remission of MCD patients with different backgrounds.
A systematic review of approaches to assess fish health responses to anthropogenic threats in freshwater ecosystems
Authors: Mallett Maxwell C , Thiem Jason D , Butler Gavin L , Kennard Mark J 
Published: May 2024

Abstract
Anthropogenic threats such as water infrastructure, land-use changes, overexploitation of fishes and other biological resources, invasive species and climate change present formidable challenges to freshwater biodiversity. Historically, management of fish and fishery species has largely been based on studies of population- and community-level dynamics; however, the emerging field of conservation physiology promotes the assessment of individual fish health as a key management tool. Fish health is highly sensitive to environmental disturbances and is also a fundamental driver of fitness, with implications for population dynamics such as recruitment and resilience. However, the mechanistic links between particular anthropogenic disturbances and changes in fish health, or impact pathways, are diverse and complex. The diversity of ways in which fish health can be measured also presents a challenge for researchers deciding on methods to employ in studies seeking to understand the impact of these threats. In this review, we aim to provide an understanding of the pathway through which anthropogenic threats in freshwater ecosystems impact fish health and the ways in which fish health components impacted by anthropogenic threats can be assessed. We employ a quantitative systematic approach to a corpus of papers related to fish health in freshwater and utilize a framework that summarizes the impact pathway of anthropogenic threats through environmental alterations and impact mechanisms that cause a response in fish health. We found that land-use changes were the most prolific anthropogenic threat, with a range of different health metrics being suitable for assessing the impact of this threat. Almost all anthropogenic threats impacted fish health through two or more impact pathways. A robust understanding of the impact pathways of anthropogenic threats and the fish health metrics that are sensitive to these threats is crucial for fisheries managers seeking to undertake targeted management of freshwater ecosystems.
miR-369-3p ameliorates diabetes-associated atherosclerosis by regulating macrophage succinate-GPR91 signalling
Authors: Rawal Shruti , Randhawa Vinay , Rizvi Syed Husain Mustafa , Sachan Madhur , Wara Akm Khyrul , Pérez-Cremades Daniel , Weisbrod Robert M , Hamburg Naomi M , Feinberg Mark W 
Published: May 2024

Abstract

Aims
Diabetes leads to dysregulated macrophage immunometabolism, contributing to accelerated atherosclerosis progression. Identifying critical factors to restore metabolic alterations and promote resolution of inflammation remains an unmet goal. MicroRNAs orchestrate multiple signalling events in macrophages, yet their therapeutic potential in diabetes-associated atherosclerosis remains unclear.

Methods and results
miRNA profiling revealed significantly lower miR-369-3p expression in aortic intimal lesions from Ldlr–/– mice on a high-fat sucrose-containing (HFSC) diet for 12 weeks. miR-369-3p was also reduced in peripheral blood mononuclear cells from diabetic patients with coronary artery disease (CAD). Cell-type expression profiling showed miR-369-3p enrichment in aortic macrophages. In vitro, oxLDL treatment reduced miR-369-3p expression in mouse bone marrow-derived macrophages (BMDMs). Metabolic profiling in BMDMs revealed that miR-369-3p overexpression blocked the oxidized low density lipoprotein (oxLDL)-mediated increase in the cellular metabolite succinate and reduced mitochondrial respiration (OXPHOS) and inflammation [Interleukin (lL)-1β, TNF-α, and IL-6]. Mechanistically, miR-369-3p targeted the succinate receptor (GPR91) and alleviated the oxLDL-induced activation of inflammasome signalling pathways. Therapeutic administration of miR-369-3p mimics in HFSC-fed Ldlr−/− mice reduced GPR91 expression in lesional macrophages and diabetes-accelerated atherosclerosis, evident by a decrease in plaque size and pro-inflammatory Ly6Chi monocytes. RNA-Seq analyses showed more pro-resolving pathways in plaque macrophages from miR-369-3p-treated mice, consistent with an increase in macrophage efferocytosis in lesions. Finally, a GPR91 antagonist attenuated oxLDL-induced inflammation in primary monocytes from human subjects with diabetes.

Conclusion
These findings establish a therapeutic role for miR-369-3p in halting diabetes-associated atherosclerosis by regulating GPR91 and macrophage succinate metabolism.