bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laryngeal involvement in pemphigus vulgaris: a proposed classification
Authors: Mahmoud A , Miziara I D , Costa K C , Santi C G , Maruta C W , Aoki V 
Published: July 2012

AbstractObjective:(1) To investigate the incidence of laryngeal involvement in a large series of patients with pemphigus vulgaris, using endoscopic examination, (2) to describe the lesions, and (3) to establish a classification of laryngeal involvement in pemphigus vulgaris based on the location of the lesions.Study design:Prospective study.Methods:A total of 40 sequentially treated pemphigus vulgaris patients, diagnosed using clinical, histological and immunofluorescence criteria, were evaluated for laryngeal manifestations using endoscopic examination. The results were used to establish a graded classification of laryngeal involvement according to the location of the lesions.Results:Active laryngeal lesions (ulcers or blisters) were found in 16 patients (40 per cent). Of these, 37.5 per cent were classified as grade I, 20 per cent as grade II, 20 per cent as grade III and 17.5 per cent as grade IV.Conclusion:Laryngeal involvement is common in pemphigus vulgaris and must be considered at the point of diagnosis. Grade I lesions are the most frequent.
A Fréchet law and an Erdős–Philipp law for maximal cuspidal windings
Authors: JAERISCH JOHANNES , KESSEBÖHMER MARC , STRATMANN BERND O. 
Published: July 2012

AbstractIn this paper we establish a Fréchet law for maximal cuspidal windings of the geodesic flow on a Riemannian surface associated with an arbitrary finitely generated, essentially free Fuchsian group with parabolic elements. This result extends previous work by Galambos and Dolgopyat and is obtained by applying extreme value theory. Subsequently, we show that this law gives rise to an Erdős–Philipp law and to various generalized Khintchine-type results for maximal cuspidal windings. These results strengthen previous results by Sullivan, Stratmann and Velani for Kleinian groups, and extend earlier work by Philipp on continued fractions, which was inspired by a conjecture of Erdős.
Relativistic self-focusing of super-Gaussian laser beam in plasma with transverse magneticfield
Authors: Gill Tarsem Singh , Mahajan Ranju , Kaur Ravinder , Gupta Suhail 
Published: July 2012

AbstractThis paper presents an investigation of a self-consistent, theoretical model, which explains the ring formation in a super-Gaussian laser beam propagating in plasma with transverse magnetic field, characterized by relativistic nonlinearity. Higher order terms (up to r4) in the expansion of the dielectric function and the eikonal have been taken into account. The condition for the formation of a dark and bright ring has been used to study focusing/defocusing of the beam. It is seen that inclusion of higher order terms does significantly affect the dependence of beam width parameter on the distance of propagation. Self-focusing of super-Gaussian beam is studied at various values of super-Gaussian coefficient, m and magnetic field. Further, we have studied some distinct features of critical power curves for varying values of magnetic field.
Clinical response to arginine vasopressin therapy after paediatric cardiac surgery
Authors: Mastropietro Christopher W. , Davalos Maria C. , Seshadri Shivaprakash , Walters Henry L. , Delius Ralph E. 
Published: July 2012

AbstractObjectiveTo describe the haemodynamic response of children who receive arginine vasopressin for haemodynamic instability after cardiac surgery and to identify clinical variables associated with a favourable response.Materials and MethodsWe reviewed patients less than or equal to 6 years undergoing open heart surgery in our institution between January, 2009 and July, 2010 who received arginine vasopressin during the first 7 days post operation. Favourable responders were defined as those in whom blood pressure was increased or maintained and catecholamine score was decreased, or blood pressure was increased by greater than or equal to 10% of baseline and catecholamine score was unchanged at 6 hours following arginine vasopressin initiation.ResultsOf the 34 patients identified, 17 (50%) patients responded favourably to arginine vasopressin. At 6 hours, the mean blood pressure was increased by 32.2% in responders as compared with 4.6% in non-responders, with a p-value less than 0.001. The mean catecholamine score decreased by 30.1% in responders and increased by 7.6% in non-responders, with a p-value less than 0.001. Anthropometric, demographic, and intra-operative variables were similar in both groups, as was maximum dose of arginine vasopressin. The median time after arrival to the intensive care unit at which arginine vasopressin was initiated, however, was later in those who responded, 20 hours as compared with those who did not, 6 hours, with a p-value equal to 0.032.ConclusionsArginine vasopressin therapy led to haemodynamic improvement in only half of the children in this study, and improvement was more likely to occur if arginine vasopressin was initiated after the post-operative night.
Role of Protease-Activated Receptor-1 in Brain Injury After Experimental Global Cerebral Ischemia
Authors: Wang Jinhu , Jin Hang , Hua Ya , Keep Richard F. , Xi Guohua 
Published: July 2012

Background and Purpose—
Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia.

Methods—
Adult male wild-type or PAR-1 knockout mice underwent a 20-minute bilateral common carotid artery occlusion or a sham operation. Behavior tests were performed before ischemia and 1, 2, and 3 days after bilateral common carotid artery occlusion. Mice were euthanized at different time points for thrombin activity, brain edema, Western blot analysis, and brain histology.

Results—
Thrombin activity and PAR-1 expression were increased in the brain after bilateral common carotid artery occlusion. Compared with wild-type mice, PAR-1 knockout mice had less brain edema formation, neuronal death, and behavior impairment after bilateral common carotid artery occlusion. In addition, bilateral common carotid artery occlusion-induced activation of mitogen-activated protein kinases was absent in PAR-1 knockout mice.

Conclusion—
PAR-1 contributes to the brain injury induced by global cerebral ischemia, which may be related to activation of mitogen-activated protein kinases.
Electricity Unit Value Prices and Purchase Quantities: U.S. Manufacturing Plants, 1963–2000
Authors: Davis Steven J. , Grim Cheryl , Haltiwanger John , Streitwieser Mary 
Published: July 2012

Abstract
We measure unit value electricity prices using 2 million annual observations on U.S. manufacturing plants from 1963 to 2000. These prices display tremendous cross-sectional dispersion, 85–95% of which reflects differences by plant location and purchase quantity. Spatial differentials decline markedly until the late 1980s for large purchasers but rise over time for small purchasers. Unit value price gaps between larger and smaller purchasers are enormous, diminish through the late 1970s, and then stabilize at still-high levels. There are major differences across states in cost and regulatory factors that we relate to the changing structure of unit value prices.
Effects of Asymmetric Latent Heating on Typhoon Movement Crossing Taiwan: The Case of Morakot (2009) with Extreme Rainfall
Authors: Wang Chung-Chieh , Kuo Hung-Chi , Chen Yu-Han , Huang Hsiao-Ling , Chung Chao-Hsuan , Tsuboki Kazuhisa 
Published: July 2012

AbstractTyphoon Morakot struck Taiwan during 6–9 August 2009, and it produced the highest rainfall (approaching 3000 mm) and caused the worst damage in the past 50 yr. Typhoon–monsoon flow interactions with mesoscale convection, the water vapor supply by the monsoon flow, and the slow moving speed of the storm are the main reasons for the record-breaking precipitation. Analysis of the typhoon track reveals that the steering flow, although indeed slow, still exceeded the typhoon moving speed by approximately 5 km h−1 (1 km h−1 = 0.28 m s−1) during the postlandfall period on 8 August, when the rainfall was the heaviest. The Cloud-Resolving Storm Simulator (CReSS) is used to study the dynamics of the slow storm motion toward the north-northwest upon leaving Taiwan. The control simulations with 3-km grid size compare favorably with the observations, including the track, slow speed, asymmetric precipitation pattern, mesoscale convection, and rainfall distribution over Taiwan. Sensitivity tests with reduced moisture content reveal that not only did the model rainfall decrease but also the typhoon translation speed increased. Specifically, the simulations consistently show a discernible impact on storm motion by as much as 50%, as the storms with full moisture move slower (~5 km h−1), while those with limited moisture (≤25%) move faster (~10 km h−1). Thus, in addition to a weak steering flow, the prolonged asymmetric precipitation in Typhoon Morakot also contributed to its very slow motion upon leaving Taiwan, and both lengthened the heavy-rainfall period and increased the total rainfall amount. The implications of a realistic representation of cloud microphysics from the standpoint of tropical cyclone track forecasts are also briefly discussed.
Comparisons of Clear-Sky Outgoing Far-IR Flux Inferred from Satellite Observations and Computed from the Three Most Recent Reanalysis Products
Authors: Chen Xiuhong , Huang Xianglei , Loeb Norman G. , Wei Heli 
Published: July 2012

Abstract
The far-IR spectrum plays an important role in the earth’s radiation budget and remote sensing. The authors compare the near-global (80°S–80°N) outgoing clear-sky far-IR flux inferred from the collocated Atmospheric Infrared Sounder (AIRS) and Clouds and the Earth’s Radiant Energy System (CERES) observations in 2004 with the counterparts computed from reanalysis datasets subsampled along the same satellite trajectories. The three most recent reanalyses are examined: the ECMWF Interim Re-Analysis (ERA-Interim), NASA Modern-Era Retrospective Analysis for Research and Application (MERRA), and NOAA/NCEP Climate Forecast System Reanalysis (CFSR). Following a previous study by X. Huang et al., clear-sky spectral angular distribution models (ADMs) are developed for five of the CERES land surface scene types as well as for the extratropical oceans. The outgoing longwave radiation (OLR) directly estimated from the AIRS radiances using the authors’ algorithm agrees well with the OLR in the collocated CERES Single Satellite Footprint (SSF) dataset. The daytime difference is 0.96 ±2.02 W m−2, and the nighttime difference is 0.86 ±1.61 W m−2. To a large extent, the far-IR flux derived in this way agrees with those directly computed from three reanalyses. The near-global averaged differences between reanalyses and observations tend to be slightly positive (0.66%–1.15%) over 0–400 cm−1 and slightly negative (−0.89% to −0.44%) over 400–600 cm−1. For all three reanalyses, the spatial distributions of such differences show the largest discrepancies over the high-elevation areas during the daytime but not during the nighttime, suggesting discrepancies in the diurnal variation of such areas among different datasets. The composite differences with respect to temperature or precipitable water suggest large discrepancies for cold and humid scenes.
Bibliometric Analysis of Health Services Research in Otolaryngology Journals
Authors: Sun Gordon H. 
Published: July 2012

ObjectiveDetermine current health services research (HSR) publication trends in major general otolaryngology journals.Study DesignBibliometric analysis.MethodsAll main issues of 8 high‐impact general‐interest otolaryngology journals published worldwide in 2002, 2005, 2008, and 2011 were searched for HSR‐related publications. To qualify as HSR, the abstract of the article must discuss access to care, cost, delivery of care, financing, health organizational or system issues, quality of care, resource utilization, and/or health outcomes. Otolaryngology topics were classified as general, pediatrics, oncology, otology and neurotology, sleep disorders, sinonasal disease, facial plastics, and/or laryngology. Other key measures included study authorship and external sponsorship or mechanism of support.ResultsOf 5958 total articles, 449 (7.5%) qualified as HSR. There was a statistically significant increase in the number of HSR publications across all journals from 2002 to 2011 (P <. 001). Outcomes research (337, 75.1%) was the most common type of HSR being published. The most common subject was oncology (112, 24.9%), whereas the least represented was trauma and facial plastics (4, 0.9%). First and corresponding authors were based in 31 countries, although the United States was the predominant country of origin. Nearly 95% of HSR articles in the current sample demonstrated multidisciplinary authorship. An estimated 22.9% of first authors and 17.8% of corresponding authors were female. Two‐thirds of HSR publications reported no external sponsor, whereas the remainder was supported most commonly by philanthropy and hospital‐based sources.ConclusionHealth services research is an international, multidisciplinary field of inquiry with an increasing presence in major otolaryngology journals.
Clinical Features of Recurrent or Persistent Benign Paroxysmal Positional Vertigo
Authors: Choi Seong Jun , Lee Jong Bin , Lim Hye Jin , Park Hun Yi , Park Keehyun , In Seung Min , Oh Jeong Hyun , Choung Yun‐Hoon 
Published: July 2012

ObjectivesTo identify clinical features and causes of recurrent or persistent benign paroxysmal positional vertigo (BPPV) and to analyze the effectiveness of frequently repeated canalith repositioning procedures (CRPs).Study DesignCase series with chart review.SettingAcademic university hospital.MethodsThe authors retrospectively reviewed the clinical records of 120 patients who were diagnosed with BPPV at the Dizziness Clinic in Ajou University Hospital, Korea, between 2004 and 2008. “Persistent” and “recurrent” BPPV were respectively defined as BPPV continuing more than 2 weeks and recurring BPPV in the same canals after at least 2 weeks of a symptom‐free interval following previous successful treatments. The authors treated patients with frequently repeated CRPs such as the modified Epley maneuver or a barbecue rotation every 2 or 3 days in the outpatient clinic.ResultsAmong 120 patients with BPPV, 93 (77.5%) were typical, 15 (12.5%) were persistent, and 12 (10.0%) were recurrent. Although the most common cause was idiopathic in both recurrent and persistent BPPV, secondary causes, including trauma, were much more common in recurrent and persistent BPPV than in typical BPPV. Typical and recurrent BPPV developed most commonly in the posterior semicircular canals. Persistent BPPV was most commonly detected in the lateral semicircular canals. After frequently repeated CRPs, 91.7% and 86.7% of the patients with recurrent or persistent BPPV, respectively, had resolution of nystagmus and vertigo.ConclusionRecurrent and persistent BPPV are not rare diseases and occur with a higher incidence than expected, especially in patients with secondary causes. However, they can be successfully treated with frequently repeated CRPs.
Detecting causality from online psychiatric texts using inter-sentential language patterns
Authors: Wu Jheng-Long , Yu Liang-Chih , Chang Pei-Chann 
Published: July 2012

Abstract

Background
Online psychiatric texts are natural language texts expressing depressive problems, published by Internet users via community-based web services such as web forums, message boards and blogs. Understanding the cause-effect relations embedded in these psychiatric texts can provide insight into the authors’ problems, thus increasing the effectiveness of online psychiatric services.

Methods
Previous studies have proposed the use of word pairs extracted from a set of sentence pairs to identify cause-effect relations between sentences. A word pair is made up of two words, with one coming from the cause text span and the other from the effect text span. Analysis of the relationship between these words can be used to capture individual word associations between cause and effect sentences. For instance, (broke up, life) and (boyfriend, meaningless) are two word pairs extracted from the sentence pair: “I broke up with my boyfriend. Life is now meaningless to me”. The major limitation of word pairs is that individual words in sentences usually cannot reflect the exact meaning of the cause and effect events, and thus may produce semantically incomplete word pairs, as the previous examples show. Therefore, this study proposes the use of inter-sentential language patterns such as ≪broke up, boyfriend>, <life, meaningless≫ to detect causality between sentences. The inter-sentential language patterns can capture associations among multiple words within and between sentences, thus can provide more precise information than word pairs. To acquire inter-sentential language patterns, we develop a text mining framework by extending the classical association rule mining algorithm such that it can discover frequently co-occurring patterns across the sentence boundary.

Results
Performance was evaluated on a corpus of texts collected from PsychPark (http://www.psychpark.org), a virtual psychiatric clinic maintained by a group of volunteer professionals from the Taiwan Association of Mental Health Informatics. Experimental results show that the use of inter-sentential language patterns outperformed the use of word pairs proposed in previous studies.

Conclusions
This study demonstrates the acquisition of inter-sentential language patterns for causality detection from online psychiatric texts. Such semantically more complete and precise features can improve causality detection performance.
Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks
Authors: Peng Wei , Wang Jianxin , Wang Weiping , Liu Qing , Wu Fang-Xiang , Pan Yi 
Published: July 2012

Abstract

Background
Identification of essential proteins plays a significant role in understanding minimal requirements for the cellular survival and development. Many computational methods have been proposed for predicting essential proteins by using the topological features of protein-protein interaction (PPI) networks. However, most of these methods ignored intrinsic biological meaning of proteins. Moreover, PPI data contains many false positives and false negatives. To overcome these limitations, recently many research groups have started to focus on identification of essential proteins by integrating PPI networks with other biological information. However, none of their methods has widely been acknowledged.

Results
By considering the facts that essential proteins are more evolutionarily conserved than nonessential proteins and essential proteins frequently bind each other, we propose an iteration method for predicting essential proteins by integrating the orthology with PPI networks, named by ION. Differently from other methods, ION identifies essential proteins depending on not only the connections between proteins but also their orthologous properties and features of their neighbors. ION is implemented to predict essential proteins in S. cerevisiae. Experimental results show that ION can achieve higher identification accuracy than eight other existing centrality methods in terms of area under the curve (AUC). Moreover, ION identifies a large amount of essential proteins which have been ignored by eight other existing centrality methods because of their low-connectivity. Many proteins ranked in top 100 by ION are both essential and belong to the complexes with certain biological functions. Furthermore, no matter how many reference organisms were selected, ION outperforms all eight other existing centrality methods. While using as many as possible reference organisms can improve the performance of ION. Additionally, ION also shows good prediction performance in E. coli K-12.

Conclusions
The accuracy of predicting essential proteins can be improved by integrating the orthology with PPI networks.
Synovial hemangiohamartoma presenting as knee pain, swelling and a soft tissue mass: a case report
Authors: Senol Serkan , Cift Hakan , Ozkan Korhan , Uygur Esat , Spinelli Maria Silvia 
Published: July 2012

Abstract

Introduction
We present a case of a patient with juxtaarticular hemangiohamartoma with a synovial extension associated with hemorrhagic synovitis and recurrent spontaneous hemarthrosis.

Case presentation
A 21-year-old Caucasian woman was admitted to our hospital complaining of pain and swelling at her knee for 6 months. In the magnetic resonance imaging, T2-weighted and fat-suppressed scans revealed a mass with high signal intensity just posterior to the patellar tendon. We performed an excisional biopsy of the mass through an anterior longitudinal incision. Excised material included arterial and venous vascular structures, which were found to be spread among the fat, connective and peripheral nerve tissues microscopically.

Conclusion
Although hemangiohamartomas are not true neoplasms, they may cause knee pain, swelling and hemarthrosis that warrant surgical resection. This lesion, although rare, should be considered in the differential diagnosis, especially in teenagers and young adults.