bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, Characterization and Water Vapor Sensitivities of Nanocrystalline SnO2 Thin Films
Authors: Chacón M. , Watson A. , Abrego I. , Ching-Prado E. , Ardinsson J. , Perez C. A. Samudio 
Published: June 2012

AbstractThin films of SnO2 were prepared via wet chemical method and deposited by dip-coating on glass substrate. The annealing temperatures of the samples were 300, 400, 500 and 600o C, respectively. Water vapor sensor responses were measured and the experimental results are tested using the Freundlich model. The better water vapor sensitivities were obtained for annealing temperatures of 500 and 600oC, respectively. The samples were characterized morphological and structurally by SEM, XRD, Mössbauer spectroscopy and Raman spectroscopy. The fringes features in the ultraviolet-visible region indicate films thickness around 370 nm. The results are discussed in terms of the fine grain size of the samples.
In vitro Shoot Regeneration and Control of Shoot Tip Necrosis in Tissue Cultures of Soymida febrifuga (Roxb.) A. Juss.
Authors: Chiruvella Kishore K. , Mohammed Arifullah , Dampuri Gayathri , Ghanta Rama Gopal 
Published: June 2012

Soymida febrifuga (Roxb.) A. Juss., (Meliaceae) an indigenous lofty deciduous tree, endemic to India, has extensive pharmacological activity. Continuous destruction of plants due to environmental and geopolitical instability has posed a major threat to endemic tree species. In vitro propagation techniques are also problematic due to high incidence of shoot tip necrosis (STN). The effect of various culture conditions on regeneration and STN of Soymida febrifuga were investigated. Nodal segments from field grown plants were used as explants and cultured on MS supplemented with different concentrations of BA, KN, NAA and IAA. The synergistic effect of BA (2 mg/l) and NAA (0.2 mg/l) induced a mean of 6.3 ± 0.09 shoots from the nodal explants with a frequency of 80.4%. Frequent subculturing of nodal explants from in vitro derived shoots increases the number of multiple shoots, but the regenerated shoots exhibited the symptoms of STN. Various factors such as strength of the media, different carbon sources activated charcoal and different calcium sources have been investigated for reducing the incidence of shoot necrosis. STN can easily be recovered by increasing the levels of calcium. Transfer of shoots showing early signs of necrosis to half strength MS supplemented with CN (556 mg/l), CP (1.0 mg/l), AC (20 mg/l) and fructose (100 mg/l) facilitated recovery of more than 98% of the shoots. Rooted plantlets produced, using the optimized protocol, were acclimatized successfully. Key words: Soymida febrifuga, Shoot regeneration, Shoot tip necrosis D.O.I. 10.3329/ptcb.v21i1.9559 Plant Tissue Cult. & Biotech. 21(1): 11-25, 2011 (June)
Rapid Shoot Regeneration from Thin Cell Layer Explants of an Endangered Medicinal Asclepiad Ceropegia spiralis L.
Authors: Murthy K. Sri Rama , Kondamudi R. 
Published: June 2012

The thin cell layers of nodes and internodes of Ceropegia spiralis L. were cultured on MS supplemented with BAP 13.32 µM/l + NAA 0.537 μM/l induced 17.34 ± 0.55 shoots showing extensive growth. Later on the organogenesis was also induced on MS containing BAP 13.32 µM/l + 2, 4-D 1.130 µM/l, whereas the medium with BAP 13.32 µM/l + 2, 4-D 4.52 µM/l has the highest callus producing ability in recalcitrants as well as in normal explants. Shoots developed were rooted best on 0.5 MS with NAA 10.74 μM/l. Optimum shoot and root multiplication was obtained within eight weeks. In vitro plantlets were successfully weaned and transferred to soil with about 90 per cent survival rate. So far, more than 650 weanlings have been produced successfully and reintroduced into nature for their recovery. Key words: Ceropegia spiralis, Thin cell layer explants, Recalcitrants, Regeneration D. O. I. 10.3329/ptcb.v21i1.9564 Plant Tissue Cult. & Biotech. 21(1): 63-73, 2011 (June)
Antiplatelet Therapy During Surgery: A Review
Authors: Bhuiyan Golam Rahman , Habib SM Ahsan , Anam Md Khairul , Hussain Ahmed Shafiqul , Islam Md Shirajul , Haque Mostasirul , Ahmed Md Khurshed 
Published: June 2012

No abstract available DOI: http://dx.doi.org/10.3329/uhj.v7i2.10845 University Heart. Journal Vol. 7, No. 2, July 2011
Computerized Tomography of Paranasal Sinuses: A Roadmap to Endoscopic Surgery
Authors: Gupta Bhumika , Tripathi Nishikanta 
Published: June 2012

ABSTRACTA detailed knowledge of sinonasal anatomy is a prerequisite for safe and successful surgery. Variation in the key landmarks of sinonasal anatomy was recorded in this study both on radiology and during surgery. These variations are especially important while working near optic nerve because a single wrong step during surgery can lead to visual loss.How to cite this articleGupta AK, Gupta B, Gupta N, Tripathi N. Computerized Tomography of Paranasal Sinuses: A Roadmap to Endoscopic Surgery. Clin Rhinol Int J 2012;5(1):1-10.
Postoperative Complications Followed by Septoplasty Comparison between Conventional Nasal Packing and Glove Finger Pack
Authors: Yousuf Aamir , Beigh Zafarullah , Malik Manzoor Ahmad , Ahmad Rafiq 
Published: June 2012

ABSTRACT

Objective
Objective of this study is to compare complications in postseptoplasty patients using conventional nasal packing and glove finger packing.

Materials and methods
In our study 95 patients who underwent septoplasty were enrolled and written consent taken for the study among these 95 patients, 50 patients were put in group A and 45 patients in group B. In group A patients glove finger packing was done and in group B patients conventional packing using medicated gauze was done and postoperative complications like postoperative pain, hemorrhage, septal perforation, toxic shock syndrome, septal hematoma, septal deviation and synechia/adhesion bands were compared between two groups, follow-up was done for both groups for 3 weeks.

Result
Our study showed that their was significantly less pain in group A patients and also their was less incidence of synechia in group A patients as compared to group B patients, their was not much difference in other complications.

Conclusion
Our results point out that glove finger pack has more advantage than conventional medicated gauze pack. We recommend use of glove finger pack after septoplasty procedure.

How to cite this article
Beigh Z, Yousuf A, Malik MA, Ahmad R. Postoperative Complications Followed by Septoplasty Comparison between Conventional Nasal Packing and Glove Finger Pack. Clin Rhinol Int J 2012;5(1):11-13.
Transnasal Endoscopic Surgery in Retro-orbital Abscess
Authors: Mohindroo NK , Sharma DR , Thakur JS , Arora Ripudaman 
Published: June 2012

ABSTRACT

Introduction
Transnasal endoscopic approach is well established in the management of subperiosteal abscess but retro-orbital abscess is commonly treated by external surgical approach. There are only two articles published on endoscopic drainage of retro-orbital abscess. We present our experience in the management of retro-orbital abscesses by transnasal endoscopic surgery.

Methods
Retrospective case charts review. Three cases with retro-orbital abscess were drained with endoscopic approach in last 5 years.

Conclusion
Role of transnasal endoscopic surgery in superior-lateral located intraorbital abscesses could not be evaluated but presented case series will further open the doors for transnasal endoscopic surgery.

How to cite this article
Thakur JS, Mohindroo NK, Sharma DR, Arora R. Transnasal Endoscopic Surgery in Retro-orbital Abscess. Clin Rhinol Int J 2012;5(1):14-16.
Chondroid Syringoma of Nose
Authors: Smitha SG , Chandregowda BV , Krishnamurthy Thejasvi 
Published: June 2012

ABSTRACT
Chondroid Syringoma is a rare cutaneous tumor which usually arises in middle age with predilection for head and neck region. We report a case of chondroid syringoma of nose with review of literature.

How to cite this article
Chandregowda BV, Smitha SG, Bhardwaj S, Krishnamurthy T. Chondroid Syringoma of Nose. Clin Rhinol Int J 2012;5(1):30-31.
A Multitrabecular Nasal Dermoid Cyst
Authors: Shinde KJ , Singh Amit Kumar 
Published: June 2012

ABSTRACT
Nasal dermoid is a rare developmental anomaly. Unlike other craniofacial dermoid, the nasal lesions can present as a cyst, a sinus or fistula and may have an intracranial extension. We report a case of 11-year-old male child presenting in the ENT OPD of Pravara Rural Hospital with a tuft of hair over the root of the nose since birth, which is uncommon presentation of nasal dermoid.

How to cite this article
Shinde KJ, Singh AK. A Multitrabecular Nasal Dermoid Cyst. Clin Rhinol Int J 2012;5(1):38-40.
Identification of Ensis siliqua Samples and Establishment of the Catch Area Using a Species-Specific Microsatellite Marker
Authors: Fernández-Tajes Juan , Arias-Pérez Aalberto , Gaspar Miguel B , Méndez Josefina 
Published: June 2012

Abstract
European Council Regulation 104/2000 states that fishery products must be labeled to indicate commercial designation of species, the production method, and the catch area. Therefore, traceability of seafood implies knowledge of the species offered to retail and their origin. Ensissiliqua is a bivalve intensively fished in Europe and sold in fresh and canned forms. Although several published methods clearly differentiate Ensis genus species, none of those assess the origin of the commercial samples. In the present study, a microsatellite marker (Esi-UDC3055F) was developed to establish the catch area of E. siliqua samples. Amplification yielded a fragment of 275 or 302 base pairs, depending on whether they were Iberian or Irish populations. The usefulness of this method was also assessed in commercial samples. The results of this study provide a reliable methodology for the identification of catch area in European E. siliqua commercial samples. The coupling of this methodology with existing techniques for razor clam species identification provides a powerful tool for traceability and labeling enforcement.
Fast Screening for Antioxidant Properties of Flavonoids from Pterogyne nitens Using Electrochemical Methods
Authors: Okumura Leonardo Luiz , Regasini  Regasini Luis Octávio , Fernandes Daniara Cristina , Silva Dulce Helena Siqueira da , Zanoni Maria Valnice Boldrin , Bolzani Vanderlan da Silva 
Published: June 2012

Abstract
A fast, low-cost, convenient, and especially sensitive voltammetric screening approach for the study of the antioxidant properties of isoquercitrin and pedalitin from Pterogyne nitens is suggested in this work. These flavonoids were investigated for their redox properties using cyclic voltammetry in nonaqueous media using N,N-dimethylformamide and tetrabutylammonium tetrafluorborate as the supporting electrolyte, a glassy carbon working electrode, Ag|AgCl reference electrode, and Pt bare wire counter electrode. The comparative analysis of the activity of rutin has also been carried out. Moreover, combining HPLC with an electrochemical detector allowed qualitative and quantitative detection of micromolecules (e.g., isoquercitrin and pedalitin) that showed antioxidant activities. These results were then correlated to the inhibition of β-carotene bleaching determined by TLC autographic assay and to structural features of the flavonoids.
Synthesis and Application of Glutaric Dihydrazide Modified Multiwalled Carbon Nanotubes for Selective Solid-Phase Extraction and Preconcentration of Cu(II), Zn(II), Ni(II), and Fe(III)
Authors: Tavallali Hossein , Zahmatkesh Saeed , Aalaei Mehdi , Abdardideh Dawood 
Published: June 2012

Abstract
An SPE method for selective separation-preconcentration of Cu(II), Zn(II), Ni(II), and Fe(III) on multiwalled carbon nanotubes (MWCNTs) modified by glutaric dihydrazide prior to flame atomic absorption spectrometric determination was investigated. The adsorption was achieved quantitatively on MWCNTs at pH 5.0, and then the retained metal ions on the adsorbent were eluted with 1 M HNO3. The effects of analytical parameters including pH of the solution, eluent type, sample volume, and matrix ions were investigated for optimization of the presented procedure. The adsorption capacity of the adsorbent at optimum conditions was found to be 33.6, 29.2, 22.1, and 36.0 mg/g for Cu(II), Zn(II), Ni(II), and Fe(III), respectively. The LOD values of the method were 0.21, 0.11, 0.24, and 0.27 μg/L for Cu(II), Zn(II), Ni(II), and Fe(III), respectively. The RSDs were lower than 3.01%. The method was applied for the determination of analytes in soil, river water, and wastewater samples with satisfactory results.
Validation of the Soleris®E. coli Method for Detection and Semi-Quantitative Determination of Escherichia coli in Foods
Authors: Foti Debra , Romano Leah , Alles Susan , Mozola Mark A 
Published: June 2012

Abstract
The performance of the Soleris®E. coli method was compared with that of the ISO 7251 most probable number (MPN) and detection reference methods for Escherichia coli. The Soleris E. coli method is a growth-based, rapid, automated system composed of temperature-controlled incubation chambers and photodiode-based optical detection devices for measurement of color changes in a prepared medium vial. A dilution of the test sample homogenate is inoculated directly into the vial. Products of E. coli metabolism alter the color of the medium over time, and this change is monitored by the Soleris instrument. The test is used in a dilute-to-specification or specification monitoring manner in which the result is positive or negative around a desired cutoff (in CFU/g) determined by the dilution and volume of sample homogenate added to the vial. Alternatively, the test is used for zero tolerance determinations (e.g., absence in 25 g) by performing an off-line pre-enrichment step followed by transfer of a portion of the pre-enrichment culture to the Soleris vial. Six E. coli strains originating from food sources were inoculated individually into six food commodities: frozen green beans, Echinacea powder, cocoa powder, sweetened condensed milk, pasteurized liquid egg, and shredded mozzarella cheese. Uninoculated samples were included in each trial. The results obtained by the ISO 7251 detection method and the Soleris E. coli method were shown to be in agreement by Chi-square analysis when the presence of E. coli was determined in 25 g of sample. Results from the Soleris E. coli dilute-to-specification method and the ISO 7251 MPN method were found to be in agreement by probability of detection statistical analysis. In inclusivity testing, 52 of 53 E. coli strains were detected within 24 h. Only a non-thermoduric strain of serotype O157:H43 was not detected. In exclusivity testing, all 31 strains tested produced negative results. Results of ruggedness experiments show that accurate results can be obtained even when the operating temperature of the Soleris instrument is set beyond normal tolerances. The internal and independent laboratory studies demonstrated that the Soleris E. coli method could be successfully utilized as an alternative to the reference methods, with a significant time savings of 2 to 3 days.
Determination of Vitamins D2 and D3 in Infant Formula and Adult Nutritionals by Ultra-Pressure Liquid Chromatography with Tandem Mass Spectrometry Detection (UPLC-MS/MS): First Action 2011.12
Authors: Stevens Jack , Dowell Dawn 
Published: June 2012

Abstract
The method for the “Determination of Vitamins D2 and D3 in Infant Formula and Adult Nutritionals by Ultra-Pressure Liquid Chromatography with Tandem Mass Spectrometry Detection (UPLC-MS/MS)” was adopted as AOAC Official First Action during the “Standards Development and International Harmonization: AOAC INTERNATIONAL Mid-Year Meeting” held June 29, 2011. During the meeting, an Expert Review Panel (ERP) evaluated the available validation information against standard method performance requirements (SMPRs) articulated by stakeholders. The method, approved by the ERP, is applicable for the determination of vitamin D (total vitamins D2 and D3). A range of products had been tested during a single-laboratory validation study. The products included butter, National Institute of Standards and Technology SRM 1849, eggs, cheese, yogurt, ready-to-eat cereal, bread, mushrooms, and tuna. The testing of the method established linearity in the range of 0.005–50 μg/mL. The recovery range was 93.4–100.9% for vitamin D2 and 102.4–106.2% for vitamin D3. The LOD and LOQ for vitamin D2 were reported as 0.20 and 0.61 μg/100 g, respectively; for vitamin D3, the reported values were 0.47 and 1.44 μg/100 g, respectively. The method met the SMPRs set by the Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN). It was, therefore, decided that the method was appropriate for Official First Action Method status.
Comparative Analysis of Chiral Drugs in View of Chemometrics
Authors: Chmielewska Aleksandra , Bączek Tomasz 
Published: June 2012

Abstract
With the development of methods for obtaining chiral compounds as potential drugs, there is also need to develop analytical methods for the separation of both enantiomers. Keeping in mind that the physical and chemical properties of both enantiomers are identical, their different nature will only be revealed in a chiral environment that is appropriately designed. Physicochemical systems can be used to predict the differences in biological activity of both enantiomers. The complexity of the problem requires the use of additional tools, which are various chemometric methods. This paper reviews the application of chemometry in the analysis of chiral drugs and discusses the effects of a combination of chromatographic, electrophoretic, and spectroscopic analysis (UV-Vis absorption spectroscopy, and near-IR spectroscopy aided by cyclodextrin inclusion complexes) with chemometrics for improving the methods of enantioseparation (experimental design), explaining the mechanisms of behavior and chiral recognition (quantitative structure-enantioselective retention relationships) and indicating chiral purity (enantiomeric excess).
Chemometrics in Pharmaceutical Analysis: An Introduction, Review, and Future Perspectives
Authors: EL-Gindy Alaa , Hadad Ghada M 
Published: June 2012

Abstract
Chemometrics is the application of statistical and mathematical methods to analytical data to permit maximum collection and extraction of useful information. The utility of chemometric techniques as tools enabling multidimensional calibration of selected spectroscopic, electrochemical, and chromatographic methods is demonstrated. Application of this approach mainly for interpretation of UV-Vis and near-IR (NIR) spectra, as well as for data obtained by other instrumental methods, makes identification and quantitative analysis of active substances in complex mixtures possible, especially in the analysis of pharmaceutical preparations present in the market. Such analytical work is carried out by the use of advanced chemical instruments and data processing, which has led to a need for advanced methods to design experiments, calibrate instruments, and analyze the resulting data. The purpose of this review is to describe various chemometric methods in combination with UV-Vis spectrophotometry, NIR spectroscopy, fluorescence spectroscopy, electroanalysis, chromatographic separation, and flow-injection analysis for the analysis of drugs in pharmaceutical preparations. Theoretical and practical aspects are described with pharmaceutical examples of chemometric applications. This review will concentrate on gaining an understanding of how chemometrics can be useful in the modern analytical laboratory. A selection of the most challenging problems faced in pharmaceutical analysis is presented, the potential for chemometrics is considered, and some consequent implications for utilization are discussed. The reader can refer to the citations wherever appropriate.
Molecular Modeling Descriptors and Analytical Chemistry Data of Antihistaminic Drugs
Authors: Konieczna Lucyna , Bober Leszek , Belka Mariusz , CIesielski Omasz , Bączek Tomasz 
Published: June 2012

Abstract
The relationships between experimental and computational descriptors of antihistamine drugs were studied using principal component analysis (PCA). Empirical data came from UV and IR spectroscopic measurements. Nonempirical data, such as structural molecular descriptors and chromatographic data, were obtained from HyperChem software. Another objective was to test whether the parameters used as independent variables (nonempirical and empirical-spectroscopic) could lead to attaining classification similar to that developed on the basis of the chromatographic parameters. To arrive at the answer to the question, a matrix of 18 × 49 data, including HPLC and UV and IR spectroscopic data, together with molecular modeling studies, was evaluated by the PCA method. The obtained clusters of drugs were consistent with the drugs' chemical structure classification. Moreover, the PCA method applied to the HPLC retention data and structural descriptors allowed for classification of the drugs according to their pharmacological properties; hence it may potentially help limit the number of biological assays in the search for new drugs.
Detection of Drug Active Ingredients by Chemometric Processing of Solid-State NMR Spectrometry Data—The Case of Acetaminophen
Authors: Paradowska Katarzyna , Jamróz Marta Katarzyna , Kobyłka Mariola , Gowin Ewelina , Mączka Paulina , Skibiński Robert , Komsta Łukasz 
Published: June 2012

Abstract
This paper presents a preliminary study in building discriminant models from solid-state NMR spectrometry data to detect the presence of acetaminophen in over-the-counter pharmaceutical formulations. The dataset, containing 11 spectra of pure substances and 21 spectra of various formulations, was processed by partial least squares discriminant analysis (PLS-DA). The model found coped with the discrimination, and its quality parameters were acceptable. It was found that standard normal variate preprocessing had almost no influence on unsupervised investigation of the dataset. The influence of variable selection with the uninformative variable elimination by PLS method was studied, reducing the dataset from 7601 variables to around 300 informative variables, but not improving the model performance. The results showed the possibility to construct well-working PLS-DA models from such small datasets without a full experimental design.
Application of Curve Resolution Algorithms in the Study Drug Photodegradation Kinetics—The Example of Moclobemide
Authors: Skibiński Robert , Komsta Łukasz 
Published: June 2012

Abstract
The photodegradation of moclobemide was studied in methanolic media. Ultra-HPLC (UHPLC)/MS/MS analysis proved decomposition to 4-chlorobenzamide as a major degradation product and small amounts of Ro 16-3177 (4-chloro-N-[2-[(2-hydroxyethyl)amino] ethyl]benzamide) and 2-[(4-chlorobenzylidene)amino]-N-[2-ethoxyethenyl]ethenamine. The methanolic solution was investigated spectrophotometrically in the UV region, registering the spectra during 30 min of degradation. Using reference spectra and a multivariate chemometric method (multi- variate curve resolution-alternating least squares), the spectra were resolved and concentration profiles were obtained. The obtained results were in good agreement with a quantitative approach, with UHPLC- diode array detection as the reference method.