bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Chemoselective (Trans)thioacetalization of Carbonyl Compounds with a Reusable Lewis Acid—Surfactant‐Combined Copper Bis(dodecyl sulfate) Catalyst in Water.
Authors: Weng Shiue‐Shien , Chang Shen‐Chun , Chang Tsuan‐Hao , Chyn Jong‐Pyng , Lee Shu‐Wei , Li Chao‐An , Chen Fong‐kuang 
Published: August 2010

AbstractA broad spectrum of aldehyde and ketone substrates can be used and many functionalities are tolerated.
ChemInform Abstract: Seven‐Component Reactions by Sequential Chemoselective Ugi—Mumm/Ugi—Smiles Reactions.
Authors: Brauch Sebastian , Gabriel Lars , Westermann Bernhard 
Published: August 2010

AbstractThe one‐pot Ugi—Mumm and Ugi—Smiles reactions of hydroxyacids (I) and (VI) give rise to peptide‐like derivatives (V) and (VII).
ChemInform Abstract: Asymmetric Acid‐Catalyzed Meerwein—Ponndorf—Verley—Aldol Reactions of Enolizable Aldehydes.
Authors: Seifert Andrea , Scheffler Ulf , Markert Morris , Mahrwald Rainer 
Published: August 2010

AbstractThe asymmetric version of the reaction is carried out under neat conditions using an alcohol, catalytic amount of TFA and dry LiClO4 as an additive and methyl silyl ether as a chiral hydrogen source.
ChemInform Abstract: Copper‐Catalyzed Asymmetric Allylic Alkylation of Halocrotonates: Efficient Synthesis of Versatile Chiral Multifunctional Building Blocks.
Authors: den Hartog Tim , Macia Beatriz , Minnaard Adriaan J. , Feringa Ben L. 
Published: August 2010

AbstractThe highly enantioselective synthesis of α‐methyl‐substituted ester (III) is reported.
ChemInform Abstract: Triquinanes: A “One‐Pot” IMDA‐Tandem Metathesis Cascade Strategy: Ring‐Closing Metathesis (RCM) Dominates Norbornene ROM!
Authors: Nguyen Natalie N. M. , Leclere Mathieu , Stogaitis Nicole , Fallis Alex G. 
Published: August 2010

AbstractOne‐pot and stepwise methods are developed to prepare the target compounds (IV).
ChemInform Abstract: Selective Synthesis of Allenes and Alkynes Through Ligand‐Controlled, Palladium‐Catalyzed Decarboxylative Hydrogenolysis of Propargylic Formates.
Authors: Ohmiya Hirohisa , Yang Mingyu , Yamauchi Yoshihiro , Ohtsuka Yuhki , Sawamura Masaya 
Published: August 2010

AbstractThe linker chain length in the ligand decides on the formation of the allenes or propargyl derivatives, with the former obtained predominantly with the shorter chain (dppe) and the latter being preferred using Ph2P‐(CH2)6‐PPh2 as a ligand.
ChemInform Abstract: A Versatile and Highly Reactive Polyfluorinated Hypervalent Iodine(III) Compound.
Authors: Schaefer Sascha , Wirth Thomas 
Published: August 2010

AbstractThe new iodine compound (V)(PFIA) effectively promotes the oxidation of sulfides to sulfoxides, conversion of sulfides into sulfoximines, homocoupling of arenes, and ring closure of unsaturated acids.
ChemInform Abstract: Chemoselective Reaction System Using a Two Inlet Micro‐Flow Reactor: Application to Carbonyl Allylation.
Authors: Amemiya Fumihiro , Fuse Keishi , Fuchigami Toshio , Atobe Mahito 
Published: August 2010

AbstractThe combined use of suitable flow mode and corresponding cathode material enables chemoselective cathodic reduction to control the product regioselectively in carbonyl allylation.
ChemInform Abstract: Highly Stereoselective Synthesis of 2,5‐Disubstituted (E,E)‐Penta‐2,4‐dienals.
Authors: Grigorieva N. Ya. , Smirnov A. G. , Popovsky V. A. , Stepanov A. V. 
Published: August 2010

AbstractTitle compounds (IV) are prepared with nearly 100% stereoselectivity as key intermediates for strobilurins A and X synthesis.
ChemInform Abstract: T3P® (Propylphosphonic Anhydride) Mediated Conversion of Carboxylic Acids into Acid Azides and One‐Pot Synthesis of Ureidopeptides.
Authors: Basavaprabhu Basavaprabhu , Narendra N. , Lamani Ravi S. , Sureshbabu Vommina V. 
Published: August 2010

AbstractThe method is high‐yielding and ecofriendly.
ChemInform Abstract: Organocatalytic Mitsunobu Reactions with 3,5‐Dinitrobenzoic Acid.
Authors: But Tracy Yuen Sze , Lu Jinni , Toy Patrick H. 
Published: August 2010

AbstractMitsunobu reaction of acid (I) is carried out using the previously reported combination of stoichiometric amounts of Ph‐I(O‐Ac)2 and DEAD as the catalyst.
ChemInform Abstract: In situ Formation of N,O‐Bidentate Ligand via the Hydrogen Bond for Highly Efficient Suzuki Reaction of Aryl Chlorides.
Authors: Yang Weibo , Liu Chun , Qiu Jieshan 
Published: August 2010

AbstractAn efficient protocol is elaborated for the phosphine‐free Suzuki reaction mediated by hydrogen bond complexes between EtOH and DMA.
ChemInform Abstract: Base Free Aryl Coupling of Diazonium Compounds and Boronic Esters: Self‐Activation Allowing an Overall Highly Practical Process.
Authors: Bonin Helene , Delbrayelle Dominique , Demonchaux Patrice , Gras Emmanuel 
Published: August 2010

AbstractA series of dioxazaborocanes (III) is prepared and successfully used as starting compounds in a base‐free Suzuki—Miyaura reaction with diazonium salts (IV).
ChemInform Abstract: Synthesis of [RhCl(CO)(cyclopentadienone)]2 from [RhCl(cod)]2 and a 1,6‐Diyne under CO: Application to Rh(I)‐Catalyzed Tandem [2 + 2 + 1] Carbonylative Cycloaddition of Diynes and Claisen Rearrangement.
Authors: Lee Sang Ick , Fukumoto Yoshiya , Chatani Naoto 
Published: August 2010

AbstractA series of bicyclo[3.3.0]octane derivatives (III) is obtained by a novel rhodium‐catalyzed carbonylative cycloaddition of diynes (I) and Claisen rearrangement.
ChemInform Abstract: Design of Reaction Media for Nucleophilic Substitution Reactions by Using a Catalytic Amount of an Amphiphilic Imidazolium Salt in Water.
Authors: Asano Keisuke , Matsubara Seijiro 
Published: August 2010

AbstractAn interfacial medium is assembled in H2O by an amphiphilic imidazolium salt to form a hydrophobic membrane including an interface consisting of ammonium species.
ChemInform Abstract: Synthesis and Reactions of 4‐Benzoyl‐1,5‐diaryl‐1H‐pyrazole‐3‐carbonyl Chlorides with Various Semi‐ and Thiosemicarbazides.
Authors: Korkusuz Elif , Yildirim Ismail 
Published: August 2010

AbstractThe chemical behavior of acid chloride (I) towards various semi‐ and thiosemicarbazides is studied.
ChemInform Abstract: Solvent‐Free Synthesis, Antiinflammatory and Anticancer Activity Evaluation of Tricyclic and Tetracyclic Benzimidazole Derivatives.
Authors: Sondhi Sham M. , Rani Reshma , Singh Jaiveer , Roy Partha , Agrawal S. K. , Saxena A. K. 
Published: August 2010

AbstractCompounds (IIIa) and (IIIc) exhibit antiinflammatory activity comparable to standard ibuprofen and compound (IX) exhibits good anticancer activity against ovary (IGR‐OV‐1), breast (MCF‐7), and CNS (SF‐295) human cancer cell lines.
ChemInform Abstract: Tandem Phenolic Oxidative Amidation—Intramolecular Diels—Alder Reaction: An Approach to the Himandrine Core.
Authors: Liang Huan , Ciufolini Marco A. 
Published: August 2010

AbstractThe reaction proceeds via an initial oxidation with PhI(OAc)2 in pure TFA as a solvent followed by heating in toluene.
ChemInform Abstract: Synthesis of α‐Alkylidene‐δ‐valerolactones via the Conjugate Addition of Ketone Enolates to Functionalized Allyl Acetates.
Authors: Ramachandran P. Veeraraghavan , Bhattacharyya Annyt 
Published: August 2010

AbstractA general synthesis of differently substituted α‐alkylidene‐δ‐valerolactones via the conjugate addition‐elimination of functionalized allylic acetates (I) with enolate nucleophiles (II),(V), and (IX) is achieved.
ChemInform Abstract: Catalytic Asymmetric Mannich—Ketalization Reaction: Highly Enantioselective Synthesis of Aminobenzopyrans.
Authors: Rueping Magnus , Lin Ming‐Yuan 
Published: August 2010

AbstractThe reaction of o‐hydroxy benzaldimines with electron‐rich alkenes proceeds under mild conditions in the presence of an air‐stable chiral catalyst and nicely complements Akiyama′s previously reported Broensted acid catalyzed reaction of aldimines with dihydrofurans and ‐pyrans leading to tetrahydroquinolines.
ChemInform Abstract: Discovery of a Spiroindane Based Compound as a Potent, Selective, Orally Bioavailable Melanocortin Subtype‐4 Receptor Agonist.
Authors: He Shuwen , et al. et al. 
Published: August 2010

AbstractDesign, multi‐step synthesis, and properties of diastereoisomeric spiroindanes of type (I) are reported.
ChemInform Abstract: Functionalized 4‐Aminoquinolines by Rearrangement of Pyrazole N‐Heterocyclic Carbenes.
Authors: Schmidt Andreas , Muenster Niels , Dreger Andrij 
Published: August 2010

AbstractHeating of betaines of type (I), (III), and (V) is found to provide pyrazole carbenes, which immediately undergo novel rearrangement to 4‐aminoquinolines.
ChemInform Abstract: One‐Step Synthesis of Thiazolo[3,2‐a]pyridines by a Multicomponent Reaction of β‐Enaminonitriles, α,β‐Unsaturated Aldehydes, and 2‐Aminothiol Hydrochlorides.
Authors: Perez‐Perrino Monica , del Villar‐Guerra Rafael , Sanudo M. Carmen , Calvo Luis A. , Gonzalez‐Ortega Alfonso 
Published: August 2010

AbstractAlthough the synthetic interest for the multicomponent preparation of the title thiazolopyridines is evident, the stereochemical control is rather low.
ChemInform Abstract: One‐Pot, Three‐Component Synthesis of Spironaphthopyrano[2,3‐d]pyrimidine‐5,3′‐indolines in Water.
Authors: Ghahremanzadeh Ramin , Amanpour Tayebeh , Sayyafi Maryam , Bazgir Ayoob 
Published: August 2010

AbstractA novel one‐pot reaction between barbituric acids, isatins, and β‐naphthol affords the previously unknown spiro compounds (IV).
ChemInform Abstract: SnCl2·2H2O‐Catalyzed One‐Pot Synthesis of 4(3H)‐Quinazolinones from Anthranilic Acid, Orthoesters, and Amines under Solvent‐Free Conditions.
Authors: Wang Min , Song Zhiguo , Zhang Tingting 
Published: August 2010

AbstractTriethyl orthoformate gives higher yields at shorter reaction time compared to the trimethyl orthoester.
ChemInform Abstract: Tetrahydroquinazoline Derivatives by Aza Diels—Alder Reaction
Authors: Cremonesi Giuseppe , Dalla Croce Piero , Gallanti Maddalena , La Rosa Concetta 
Published: August 2010

Abstractof N‐(2‐chloromethylphenyl)benzenesulfonamides with N‐benzylideneamines
ChemInform Abstract: Synthesis and Photophysical Properties of 2,3,5,6,7,8‐Hexasilabicyclo[2.2.2]octan‐1‐yl‐Substituted Arenes.
Authors: Shimizu Masaki , Kawaguchi Tomoaki , Nakagawa Hisashi , Oda Katsunari , Hiyama Tamejiro 
Published: August 2010

AbstractIncorporation of the title polysilacage moiety into chromophores such as biphenyl, terphenyl, stilbene and tolan is found to induce bathochromic shifts of absorption and fluorescence spectra as well as enhancements of molar extinction coefficients and fluorescence quantum yields.
ChemInform Abstract: 4‐Phosphorylated 1,2‐Disubstituted Imidazoles.
Authors: Huryeva A. N. , Marchenko A. P. , Koidan G. N. , Yurchenko A. A. , Zarudnitskii E. V. , Pinchuk A. M. , Kostyuk A. N. 
Published: August 2010

AbstractA facile route to 4‐phosphorylated imidazoles starting from readily available 5‐diamidoselenophosphoryl‐imidazoles (VI) is developed.
ChemInform Abstract: Dimethylsilylaminophosphane Heterocyclization of Isothiocyanates to Diazaphosphole‐Thiones Through Zwitterionic Intermediates.
Authors: Petrov Petar Y. , Angelov Christo M. , McDonald Robert , Alexiev Alexi , Cavell Ronald G. 
Published: August 2010

AbstractSilylaminophosphane (I) reacts with isothiocyanates to novel five‐membered heterocyclic diazaphosphole‐thiones (III).
ChemInform Abstract: Bioisostere of Valtrate, anti‐HIV Principle by Inhibition for Nuclear Export of Rev.
Authors: Tamura Satoru , Shimizu Nobuhiro , Fujiwara Katsuaki , Kaneko Masafumi , Kimura Tominori , Murakami Nobutoshi 
Published: August 2010

AbstractA synthetic pathway to 5,6‐dihydrovaltrate (I) is described using an asymmetric Diels—Alder reaction between diethyl fumarate and cyclopentadiene as key step (catalyst and product configuration are not specified, yield quant., 95% e.e.).
ChemInform Abstract: 2‐Cyano‐3,10‐dioxooleana‐1,9(11)‐dien‐28‐oic Acid Anhydride. A Novel and Highly Potent Antiinflammatory and Cytoprotective Agent.
Authors: Honda Tadashi , Padegimas Eric M. , David Emilie , Sundararajan Chitra , Liby Karen T. , Williams Charlotte , Sporn Michael B. , Visnick Melean 
Published: August 2010

AbstractTitle compound (I) is easily synthesized as first example of an oleane triterpenoid anhydride.
ChemInform Abstract: Synthesis of the ABC Ring Fragment of Brevisin, a New Dinoflagellate Polycyclic Ether.
Authors: Ohtani Naohito , Tsutsumi Ryosuke , Kuranaga Takefumi , Shirai Tomohiro , Wright Jeffrey L. C. , Baden Daniel G. , Satake Masayuki , Tachibana Kazuo 
Published: August 2010

AbstractThe polycyclic ether brevisin is isolated from the red‐tide dinoflagellate K.
ChemInform Abstract: New Cyanoglycosides, Hydracyanosides D, E, and F, from the Leaves of Hydrangea macrophylla.
Authors: Wang Zhibin , Nakamura Seikou , Matsuda Hisashi , Wu Lijun , Yoshikawa Masayuki 
Published: August 2010

AbstractTogether with 17 known compounds, three new cyanoglycosides named hydracyanosides D (I), E (II), and F (III) are isolated from the leaves of Hydrangea macrophylla cultivated in China.
ChemInform Abstract: Synthesis and Antifungal Activity of 2‐Hydroxy‐4,5‐methylenedioxyaryl Ketones as Analogues of Kakuol.
Authors: Musso Loana , Dallavalle Sabrina , Merlini Lucio , Farina Gandolfina 
Published: August 2010

AbstractA diversity of structural analogues of kakuol (Ia) is prepared and their antifungal activity against several pathogenic strains is studied in detail.
ChemInform Abstract: A Concise Synthesis of Sex Pheromone of Mediterranean Fruit Fly, Ceratitis capitata via Lithiated Carbanion Derived from Enephosphoramide.
Authors: Olszewski Tomasz Krzysztof , Grison Claude 
Published: August 2010

AbstractArising from retrosynthetic analysis, assets and drawbacks of two different approaches to title compound (VII) are compared.
ChemInform Abstract: Zinc Oxide Nanorod Based Photonic Devices: Recent Progress in Growth, Light Emitting Diodes and Lasers
Authors: Willander M. , Nur O. , Zhao Q. X. , Yang L. L. , Lorenz M. , Cao B. Q. , Perez J. Zuniga , Czekalla C. , Zimmermann G. , Grundmann M. , et al. et al. 
Published: August 2010

AbstractReview: 280 refs.
ChemInform Abstract: Novel Phosphorus and Nitrogen Donor Ligands Bearing Secondary Functionalities for Applications in Homogeneous Catalysis
Authors: Pleier Anna‐Katharina , Sun Yu , Schubert Anett , Zabel Dirk , May Claudia , Reis Andreas , Wolmershauser Gotthelf , Thiel Werner R. 
Published: August 2010

AbstractReview: 80 refs.
RelHunter: a machine learning method for relation extraction from text
Authors: Fernandes Eraldo R. , Milidiú Ruy L. , Rentería Raúl P. 
Published: August 2010

Abstract
We propose RelHunter, a machine learning-based method for the extraction of structured information from text. RelHunter’s key idea is to model the target structures as a relation over entities. Hence, the modeling effort is reduced to the identification of entities and the generation of a candidate relation, which are simpler problems than the original one. RelHunter fits a very broad spectrum of complex computational linguistic problems. We apply it to five tasks: phrase chunking, clause identification, hedge detection, quotation extraction, and dependency parsing. We compare RelHunter to token classification approaches through several computational experiments on seven multilingual corpora. RelHunter outperforms the token classification approaches by 2.14% on average. Moreover, we compare the derived systems against state-of-the-art systems for each corpus. Our systems achieve state-of-the-art performances for three corpora: Portuguese phrase chunking, Portuguese clause identification, and English quotation extraction. Additionally, the derived systems show good quality performance for the other four corpora.
Thermal expansion coefficients and composition of sputter-deposited silicon oxynitride thin films
Authors: McKerracher I R , Fu L , Tan H H , Jagadish C 
Published: August 2010

Modern technology is heavily reliant on silicon dioxide and silicon nitride thin films. These films have many electronic and optical applications, and in some cases silicon oxynitride films of intermediate composition are desirable. We have systematically deposited several SiO
x
N
y
films by magnetron sputter deposition and thoroughly investigated their composition with Rutherford backscattering spectrometry and optical measurements. The as-deposited stress in these thin films was also measured and all were found to be compressive.
Temperature-dependent stress measurements up to 450 °C were then used to extract the biaxial modulus and coefficient of thermal expansion for each SiO
x
N
y
. The SiO2-like films exhibit negative thermal expansion, which is consistent with a strong but porous structure. Increasing the nitrogen content results in the thermal expansion coefficient increasing towards values reported elsewhere for Si3N4.
Absolute ground-state nitrogen atom density in a N2/CH4 late afterglow: TALIF experiments and modelling studies
Authors: Es-sebbar Et , C-Gazeau M , Benilan Y , Jolly A , Pintassilgo C D 
Published: August 2010

Following a first study on a late afterglow in flowing pure nitrogen post discharge, we report new two-photon absorption laser-induced fluorescence (TALIF) measurements of the absolute ground-state atomic nitrogen density N(4S) and investigate the influence of methane introduced downstream from the discharge by varying the CH4 mixing ratio from 0% up to 50%. The N (4S) maximum density is about 2.2 × 1015 cm−3 in pure N2 for a residence time of 22 ms and does not change significantly for methane mixing ratio up to ∼15%, while above, a drastic decrease is observed. The influence of the residence time has been studied.
A kinetic model has been developed to determine the elementary processes responsible for the evolution of the N (4S) density in N2/CH4 late afterglow. This model shows the same decrease as the experimental results even though absolute density values are always larger by about a factor of 3. In the late afterglow three-body recombination dominates the loss of N (4S) atoms whatever the CH4 mixing ratio. For high CH4 mixing ratio, the destruction process through collisions with CH3, H2CN and NH becomes important and is responsible for the observed decrease of the N (4S) density.
Gene function prediction using semantic similarity clustering and enrichment analysis in the malaria parasite Plasmodium falciparum
Authors: Tedder Philip M. R. , Bradford James R. , Needham Chris J. , McConkey Glenn A. , Bulpitt Andrew J. , Westhead David R. 
Published: August 2010

Abstract
Motivation: Functional genomics data provides a rich source of information that can be used in the annotation of the thousands of genes of unknown function found in most sequenced genomes. However, previous gene function prediction programs are mostly produced for relatively well-annotated organisms that often have a large amount of functional genomics data. Here, we present a novel method for predicting gene function that uses clustering of genes by semantic similarity, a naïve Bayes classifier and ‘enrichment analysis’ to predict gene function for a genome that is less well annotated but does has a severe effect on human health, that of the malaria parasite Plasmodium falciparum.
Results: Predictions for the molecular function, biological process and cellular component of P.falciparum genes were created from eight different datasets with a combined prediction also being produced. The high-confidence predictions produced by the combined prediction were compared to those produced by a simple K-nearest neighbour classifier approach and were shown to improve accuracy and coverage. Finally, two case studies are described, which investigate two biological processes in more detail, that of translation initiation and invasion of the host cell.
Availability: Predictions produced are available at http://www.bioinformatics.leeds.ac.uk/∼bio5pmrt/PAGODA
Contact: D.R.Westhead@leeds.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
Alpha‐receptor blockade improves muscle perfusion and glucose uptake in heart failure
Authors: Gomes Marc E.R. , Mulder Alexandra , Bellersen Louise , Verheugt Freek W.A. , Smits Paul , Tack Cees J. 
Published: August 2010

AimsAlpha‐adrenergic receptor‐mediated vasoconstriction might underlie the insulin resistance seen in conditions associated with increased sympathetic tone, like chronic heart failure (CHF). Alpha‐adrenergic receptor blockade by phentolamine could improve forearm blood flow (FBF) and forearm glucose uptake (FGU) in CHF patients.Methods and resultsIn 8 CHF patients and in 12 healthy volunteers, FBF (plethysmography) and FGU were measured in both forearms during a 150 min hyperinsulinaemic euglycaemic clamp procedure. During the final 30 min of the clamp, phentolamine was infused into one arm (experimental arm) at a dose of 5.0 μg; min−1 dL−1 of forearm volume. Insulin infusion (t = 0–120 min) increased FGU in the two groups, without affecting FBF. In the CHF group, α‐adrenergic receptor blockade by phentolamine (t = 120–150 min) further increased FGU in the experimental arm from 3.0 ± 0.7 to 5.0 ± 0.9 μmol min−1 dL−1 (P = 0.03). Forearm glucose uptake in the contralateral forearm remained unchanged. In the control group, phentolamine infusion did not increase FGU in the experimental forearm. The increase in blood flow in response to phentolamine was similar in both groups (CHF: 2.1 ± 0.3–7.5 ± 1.7 mL min−1 dL−1, P < 0.001; controls 1.5 ± 0.2–5.5 ± 0.8 mL min−1 dL−1, P < 0.001 for both, CHF vs. control, P = 0.2). Phentolamine did not affect FBF in the control arm in either group.ConclusionAlpha‐adrenergic receptor blockade improves FGU in CHF patients. As the increase in FBF is similar in controls and CHF patients, this might be explained by an improved glucose‐extraction capacity in CHF patients.
Factors influencing organic food purchase in India – expert survey insights
Authors: Chakrabarti Somnath 
Published: August 2010

PurposeThe paper aims to document the findings of an expert survey in the organic food category in India. It seeks to highlight the relative importance attached by the experts to key explanatory variables in the consumers' purchase process of organic food. It attempts to integrate with the relevant consumer survey findings published in India in recent times in organic food category.Design/methodology/approachThe list of experts was prepared by including regular and well‐known speakers in different agri enclaves and summits and who are members of different food industry bodies. Experts were contacted through judgmental sampling method. Feedback on the expert questionnaires was collected from July to October 2007 from 33 highly knowledgeable senior experts primarily through face‐to‐face personal surveys and through e‐mail surveys.FindingsImportance placed on health motivation has the highest average rating and is one of the lowest standard deviations among the explanatory variables in the expert survey. Experts also rate the importance of the three mentioned attitudes (about conviction about utility of organic food, reputation of store and certification process‐related information), organic food‐specific consumer innovativeness, organic food‐specific consumer opinion leadership, word of mouth (WOM) (activity), WOM (praise) and affective commitment about the store to be high in the consumers' purchase process.Originality/valueThe novelty of the paper lies in the fact that it addresses the key issues facing the organic food category in India from an expert survey point of view.