bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous estimation of 16α‐hydroxycleroda‐3,13(14) Z‐dien‐15,16‐olide from Polyalthia longifolia and its metabolite in hamster plasma: application to pharmacokinetic study
Authors: Bhatta R. S. , Kumar Devendra , Chhonker Y. S. , Kumar Deepak , Singh Suriya P. , Sashidhara Koneni V. , Jain G. K. 
Published: July 2011

ABSTRACTA selective and sensitive LC–MS‐MS method was developed and validated for simultaneous estimation and pharmacokinetic studies of 16α‐hydroxycleroda‐3,13(14) Z‐dien‐15,16‐olide (K‐09) obtained from Polyalthia longifolia and its metabolite (K‐9T), a novel antidyslipidemic agent. Sample clean‐up involved liquid–liquid extraction of both the analytes and internal standard (rosuvastatin) from 200 μL of hamster plasma. The analytes were chromatographically separated on a Symmetry‐Shield C18 (5 µm, 4.6 × 150 mm) column, using acetonitrile–0.1% aqueous formic acid (92:08, v/v) as the mobile phase. Detection was performed using negative ion electrospray ionization in multiple reaction monitoring mode. The MS/MS response was linear over the concentration range 1.56–200 ng/mL, with a correlation coefficient (r2) of 0.998 or better. The within‐ and between‐batch precisions (relative standard deviation, %RSD) and the accuracy (percentage bias) were within acceptable limits as per FDA guidelines. The validated method was successfully applied to reveal the pharmacokinetic parameters of K‐09 and metabolite after oral administration. This method will therefore be highly useful for future studies of K‐09 and metabolite K‐9T pharmacokinetics in preclinical and clinical studies. Copyright © 2011 John Wiley & Sons, Ltd.
Family Climate and Recovery in Adolescent Onset Eating Disorders: A Prospective Study
Authors: Nilsson Karin , Engström Ingemar , Hägglöf Bruno 
Published: July 2011

AbstractObjectiveThis prospective study investigated the self‐assessed family climate of adolescent patients and their parents during treatment of and recovery from eating disorders.MethodOne hundred two girls aged 13–17 years with eating disorders, answered the self‐report Family Climate Scale (FCS) and Eating Disorders Inventory for Children at initial assessment and after 18 and 36 months. The FCS was also answered by their parents at the same time points.ResultsSelf‐assessed family climate and eating disorder symptoms were similar for recovered (R) and nonrecovered (NR) adolescents at initial assessment and at 18 months. At 36 months, FCS Closeness was higher for R, and FCS Distance was lower for R compared with NR. Parents of R adolescents had higher scores on FCS Closeness and lower scores on FCS Chaos compared with parents of NR adolescents at the 36‐month follow‐up.ConclusionSelf‐reported family climate was associated with recovery. Changes in eating disorder symptoms preceded changes in family climate. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
Generation companies' adaptive bidding strategies using finite‐state automata in a single‐sided electricity market
Authors: Sheblé Gerald B. , Gutierrez‐Alcaraz Guillermo 
Published: July 2011

SUMMARYThis paper explores the use of genetic algorithms (GAs) in the development of the bidding strategies used by generation companies under two different market clearing mechanisms, uniform pricing and pay‐as‐bid pricing. The bidding strategies are represented by two modifications of a classical data processing structure known as finite‐state automata. Semi‐fixed fitness function and co‐evolutionary fitness function were incorporated in our GA. A third simple representation to obtain a comparison baseline for the other two representations, showing how their behaviors compare with a “standard” solution, was also incorporated. The strategies developed by our method were adaptive, and all GA types were based on maximizing profit in a competitive bidding situation. Copyright © 2011 John Wiley & Sons, Ltd.
Improved production implicit continuous‐fluid Eulerian method for compressible flow problems in Uintah
Authors: Tran L. T. , Berzins M. 
Published: July 2011

SUMMARYThe implicit continuous‐fluid Eulerian (ICE) method is a successful and widely used semi‐implicit finite‐volume method that applies to flows that range from supersonic to subsonic regimes. The classical ICE method has been expanded to problems in multiphase flow, which spans a wide area of science and engineering. The ICE method is utilized by the Center for the Simulation of Accidental Fires and Explosions code Uintah written at the University of Utah to simulate explosions, fires and other fluid and fluid‐structure interaction phenomena. The ICE method used in Uintah (referred to here as Production ICE) is described in many papers by Kashiwa at Los Alamos National Laboratory and Harman at University of Utah. However, Production ICE does not perform as well as many current methods for compressible flow problems governed by the Euler equations. We show, via examples, that changing the nonconservation form of the solver in Production ICE to a conservation form improves the numerical solutions. In addition, the use of slope limiters makes it possible to suppress the nonphysical oscillations generated by the ICE method in conservation form. This new form of ICE is referred to as IMPICE, the IMproved Production ICE method. The accuracy of IMPICE for one‐dimensional Euler equations is investigated by using a number of test cases. Copyright © 2011 John Wiley & Sons, Ltd.
High‐Temperature Electrochemical Characterization of Ru Core Pt Shell Fuel Cell Catalyst
Authors: Bokach D. , de la Fuente J. L. G. , Tsypkin M. , Ochal P. , Endsjø I. C. , Tunold R. , Sunde S. , Seland F. 
Published: July 2011

AbstractThe electrooxidation of methanol was studied at elevated temperature and pressure by cyclic voltammetry and constant potential experiments at real fuel cell electrocatalysts. Ruthenium core and platinum shell nanoparticles were synthesized by a sequential polyol route, and characterized electrochemically by CO stripping at room temperature to quickly confirm the structure of the synthesized core–shell structure as compared to pure commercial Pt/C and Pt–Ru/C alloy catalysts. A significant promotional effect of Pt decorated Ru cores in the methanol oxidation was found at elevated temperatures and rather high‐electrode potentials. A negative potential shift of the methanol oxidation peak is observed for the Ru@Pt/C core–shell catalyst at moderate temperatures, while a significant shift to positive potentials of the methanol oxidation peak occurs for Pt/C catalysts. The onset potential for methanol oxidation is lowered some 200 mV from room temperature and up to 120 °C for all electrocatalysts, indicating that it is the thermal activity of water adsorption that dictates the onset potential. Direct methanol fuel cell experiments showed only small performance differences between Ru@Pt/C and Pt/C anode electrocatalysts, suggesting the necessity of render possible the formation of surface oxygen species at lower electrode potentials.
Characterising soil moisture in transport corridor environments using airborne LIDAR and CASI data
Authors: Hardy Andrew J. , Barr Stuart L. , Mills Jon P. , Miller Pauline E. 
Published: July 2011

AbstractMuch of the world's transport networks are located on cutting and embankment earthworks. In the UK, many of these earthwork structures were constructed in the mid‐19th century and are susceptible to slope instability. Instability in transport corridors tends to be triggered by an increase in pore water pressure, which is directly influenced by an increase in soil moisture. This study explores the integration of high spatial resolution airborne (1 m) LIght Detection And Ranging (LIDAR) and Compact Airborne Spectrographic Imager (CASI) imagery to characterize soil moisture distribution for a transport corridor near Haltwhistle, UK. The distribution of soil moisture is estimated using these sensors through techniques that are relatively unaffected by, or make use of, the presence of vegetation, unlike other techniques using thermal, shortwave and microwave sensors. Terrain analysis calculations of potential solar radiation and a topographic wetness index were applied to a DEM interpolated from the LIDAR point data. The CASI imagery was used to map Ellenberg moisture indicator values using partial least squares regression. Individually, the remotely sensed metrics were found to have poor correlations with observed soil moisture. However, improvements could be made using an integrated model which demonstrated a correlation coefficient of 0·68. The resulting integrated model showed soil moisture content to increase on north‐facing earthworks and towards the toe of earthwork slopes. Concentrations of moisture were also predicted in cuttings where water is contributed from areas surrounding the earthworks. Copyright © 2011 John Wiley & Sons, Ltd.
A Framework for generalized reference image reconstruction methods including HYPR‐LR, PR‐FOCUSS, and k‐t FOCUSS
Authors: Chen Liyong , Samsonov Alexey , DiBella Edward V.R. 
Published: July 2011

AbstractPurpose:To investigate the relationships among highly constrained back projection (HYPR)‐LR, projection reconstruction focal underdetermined system solver (PR‐FOCUSS), and k‐t FOCUSS by showing how each method relates to a generalized reference image reconstruction method. That is, the generalized series model employs a fixed reference image and multiplicative corrections—that model is extended here to consider reference images more broadly, both in image space and in transform spaces (x‐t and x‐f spaces), and that can evolve with iteration.Materials and Methods:Theoretical relationships between the methods were derived. Computer simulations were done to compare HYPR‐LR to one iteration of PR‐FOCUSS. The generalized reference approaches applied in the x‐t or x‐f domain were compared using computer simulation, five cardiac cine imaging datasets, and six myocardial perfusion datasets.Results:PR‐FOCUSS and HYPR‐LR gave comparable errors, with PR‐FOCUSS slightly outperforming HYPR‐LR. The baseline image is important to the performance of k‐t FOCUSS and x‐t FOCUSS, as demonstrated by results from cardiac cine imaging. For cardiac perfusion reconstructions with the use of a temporal average image as the baseline image, k‐t FOCUSS gave lower errors than x‐t FOCUSS.Conclusion:HYPR‐LR and PR‐FOCUSS are closely related: both work for radial sampling and use reference images in the x‐t domain; HYPR‐LR is an approximate implementation of the generalized reference framework, while PR‐FOCUSS is a conjugate gradient implementation of the generalized reference framework. The superiority of generalized reference approaches applied in the x‐t or x‐f domain was sensitive to the characteristics of the acquired data and to the baseline image used. J. Magn. Reson. Imaging 2011;. © 2011 Wiley‐Liss, Inc.
Zoom imaging for rapid aortic vessel wall imaging and cardiovascular risk assessment
Authors: Hussain Tarique , Clough Rachel E. , Cecelja Marina , Makowski Marcus , Peel Sarah , Chowienczyk Philip , Schaeffter Tobias , Greil Gerald , Botnar Rene 
Published: July 2011

AbstractPurpose:To demonstrate the utility of a “reduced field‐of‐view” (zoom imaging) technique to accelerate free‐breathing, ECG‐triggered, turbo‐spin‐echo black‐blood sequences, which have been previously described to detect subclinical aortic atherosclerosis.Materials and Methods:Fifteen healthy volunteers underwent MRI of the thoracic and abdominal aorta. Imaging with the conventional full field‐of‐view sequence was compared with zoom imaging. Total scan time, image quality (i.e., contrast‐to‐noise ratio and vessel wall sharpness) and vessel wall thickness were analyzed. A subgroup of 10 volunteers also underwent acceleration of imaging using sensitivity encoding (SENSE) for comparison.Results:Zoom imaging significantly reduced imaging time from a mean of 41 ± 9 min (conventional imaging) to 15 ± 0.5 min (P < 0.01). There was no difference in image quality between conventional and zoom imaging with respect to CNR (10.1 ± 6 versus 10.1 ± 6) or vessel wall sharpness (38 ± 4% versus 39 ± 4%). Furthermore, Bland Altman plots showed excellent agreement in vessel wall thickness measurements using the two methods. In comparison, SENSE not only reduced CNR but also resulted in underestimation of vessel wall thickness compared with the conventional sequence.Conclusion:Zoom imaging allows accurate and time‐efficient imaging of the abdominal and thoracic aorta for cardiovascular risk prediction. In this application, it is preferable to SENSE. J. Magn. Reson. Imaging 2011;. © 2011 Wiley‐Liss, Inc.
Tissue conservation using circular defect with dog‐ear deformities excision technique
Authors: Lee Thomas S. , Murakami Craig S. , Suryadevara Amar C. 
Published: July 2011

AbstractObjectives:Compare circular defect with dog‐ear deformities excision (CDDE) technique to 3:1 fusiform excision technique when removing facial lesions to analyze which technique provides superior wound closure.Methods:Identical 1‐cm circular skin defects were created on bilateral cheek, forehead, and parietal scalp on three fresh cadavers. Similarly, using four fresh cadavers, identical 2‐cm circular skin defects were created on bilateral cheek, forehead, and scalp. In both the 1‐cm and 2‐cm circular defects (n = 19), a 3:1 fusiform excision and closure was performed on one side of the cadaver head for control. On the opposite side, CDDE excision technique was performed. The following measurements were recorded: circumferential incision length after tissue excision, average of wound widening widths after an approximation suture was placed at the halfway point, and the final incision length after primary closure. Final incision length upon closure was divided by the original defect size to obtain a final incision length to defect ratio. A paired t‐test was performed on all variables for analysis.Results:When using the CDDE excision technique, there were statistically significant decreases in circumference, average wound widening, final incision length in both 1‐cm and 2‐cm circular defects (P < .01). The final incision length upon closure to defect ratio in CDDE excision was approximately 2.5:1, whereas 3:1 fusiform excision resulted in the final incision length to defect ratio of approximately 3.5:1.Conclusions:When compared to fusiform excision technique, CDDE excision technique appears to minimize tissue excision, decrease wound widening and the final incision length.
Subthalamic nucleus stimulation affects incentive salience attribution in Parkinson's disease
Authors: Serranová Tereza , Jech Robert , Dušek Petr , Sieger Tomáš , Růžička Filip , Urgošík Dušan , Růžička Evžen 
Published: July 2011

AbstractDeep brain stimulation (DBS) of the subthalamic nucleus (STN) can induce nonmotor side effects such as behavioral and mood disturbances or body weight gain in Parkinson's disease (PD) patients. We hypothesized that some of these problems could be related to an altered attribution of incentive salience (ie, emotional relevance) to rewarding and aversive stimuli. Twenty PD patients (all men; mean age ± SD, 58.3 ± 6 years) in bilateral STN DBS switched ON and OFF conditions and 18 matched controls rated pictures selected from the International Affective Picture System according to emotional valence (unpleasantness/pleasantness) and arousal on 2 independent visual scales ranging from 1 to 9. Eighty‐four pictures depicting primary rewarding (erotica and food) and aversive fearful (victims and threat) and neutral stimuli were selected for this study. In the STN DBS ON condition, the PD patients attributed lower valence scores to the aversive pictures compared with the OFF condition (P < .01) and compared with controls (P < .01). The difference between the OFF condition and controls was less pronounced (P < .05). Furthermore, postoperative weight gain correlated with arousal ratings from the food pictures in the STN DBS ON condition (P < .05 compensated for OFF condition). Our results suggest that STN DBS increases activation of the aversive motivational system so that more relevance is attributed to aversive fearful stimuli. In addition, STN DBS–related sensitivity to food reward stimuli cues might drive DBS‐treated patients to higher food intake and subsequent weight gain. © 2011 Movement Disorder Society
Characterization of SrTiO3 thin films at microwave frequencies using coplanar waveguide linear resonator method
Authors: Marulanda J. I. , Cremona M. , Santos R. , Carvalho M. C. R. , Demenicis L. S. 
Published: July 2011

AbstractExperimental characterization of the dielectric properties of a SrTiO3 (STO) thin film in the microwave frequency range at room temperature is presented. The coplanar waveguide linear resonator technique, which is already well‐established for thick film characterization, was tailored and improved to allow thin film measurements. Experimental results are in very good agreement with theoretical analysis. Using this approach, a relative dielectric constant of 95 and a loss tangent less than 10−3 were measured for a STO film with 4.2 μm of thickness deposited by radio frequency (RF) magnetron sputtering. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2418–2422, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26233
Integrated coherent receiver for linear optical phase demodulation
Authors: Krishnamachari Uppiliappan , Ristic Sasa , Ramaswamy Anand , Johansson Leif A. , Chen Chin‐Hui , Klamkin Jonathan , Bhardwaj Ashish , Rodwell Mark J. , Bowers John E. , Coldren Larry A. 
Published: July 2011

AbstractAn ultracompact coherent receiver with negative feedback was developed for highly linear phase demodulation.The receiver demonstrates a spur‐free dynamic range of 122 dB Hz2/3 at a signal frequency of 300 MHz. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2343–2345, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26236
Wave scattering from rough building surfaces in a virtual city model for the land mobile satellite propagation channel
Authors: Valtr Pavel , Perez‐Fontan Fernando 
Published: July 2011

AbstractThe diffuse multipath component is studied in land mobile satellite (LMS) built‐up propagation scenarios. The method of physical optics (PO) was implemented to model scattering from rough building facades. The results in terms of received power time‐series are used to obtain the average multipath power level relative to free space for several roughness levels and various elevations and azimuths toward the transmitter. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2310–2314, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26237
A new numerical technique for analysis of periodic structures
Authors: Yoo Kyungho , Mehta Nikhil , Mittra Raj 
Published: July 2011

AbstractWe introduce a numerically efficient technique to analyze doubly infinite periodic structures by applying Floquet's theorem and the Characteristic Basis Function Method to the corresponding truncated array.We use reciprocity to compute the reflection coefficient of the array and avoid integration of induced currents for calculating scattered far fields by the periodic Green's function. We show that our method is able to analyze both planar and nonplanar frequency selective surfaces by comparing the reflection coefficient of frequency selective surface of standard elements with other codes. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2332–2340, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26250
Mechanically induced long‐period fiber grating array sensor
Authors: Lee Namkwon , Song Jaewon , Park Jaehee 
Published: July 2011

AbstractThis article presents the experimental characterization of a mechanically induced long‐period fiber grating (MLPFG) array sensor for measuring the amplitude and width of an applied weight as well as detecting its position. The MLPFG array sensor consists of an optical fiber placed between a rubber cover and a 45‐cm‐long metal bar with round grooves on its upper surface divided into 10 different grating periods. The grating periods are sequentially increased by 10 μm from 690 to 780 μm, and the number of grooves per grating period is 60. Experimental results show that the MLPFG array sensor can be used for measuring the amplitude of an applied weight from the optical attenuation at the resonance wavelength, measuring the loading width from the full width at half maximum of the dip, and detecting the position of the applied weight from the resonance wavelength. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2295–2298, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26289
A compact mimo antenna with improved isolation bandwidth for mobile applications
Authors: Yu Yeonsik , Ji Jeongkeun , Seong Wonmo , Choi Jaehoon 
Published: July 2011

AbstractAn internal MIMO antenna for mobile applications is proposed. Helical‐type antenna elements are used to construct the MIMO system. The resonance frequencies of the MIMO antenna are controlled by the number of turns per helix. A multi suspended line with lumped elements is used to reduce the coupling between the antenna elements. The antenna elements are located at the top edges of the ground plane, and a decoupling network is inserted between the two antenna elements. The performance of the prototype antenna is analyzed through the scattering parameters, actual diversity gain, envelope correlation coefficient, and channel capacity measurements. The isolation characteristic and MIMO performance can be improved by using the decoupling network at the LTE service band. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2314–2317, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26293
Multiband planar metamaterials
Authors: Sabah Cumali 
Published: July 2011

AbstractNew method for design and realizing multiband metamaterial is presented.For this purpose, resonator‐based metamaterial is designed and investigated by both simulation and experiment with well agreement. By serially arranging the nonconcentric open loop metallic elements with different dimensions, the structure exhibits multipassbands related to the metamaterials' unique features. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2255–2258, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26296
Design of UHF radio frequency identification metal tag antenna using T‐shaped slot
Authors: Park Sang Yong , Lee Jung Nam , Park Jong Kweon 
Published: July 2011

AbstractIn this article, we have proposed a novel ultra high frequency (UHF) radio frequency identification (RFID) metal tag antenna mountable on the metallic surface. Three techniques (T‐shaped slot, two rectangular slots for impedance matching, and air gap technique for reading distance enhancement) are used to obtain a good performance of metal tag antenna on the metallic surface. All simulations are carried out by Ansoft HFSS software. Moreover, by fabricating the antenna, the simulation results are verified by experimental data. Good performances such as reading distance and sensitivity have been observed. Details of the proposed antenna design and the simulated and measured results are presented and discussed. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:2251–2255, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26297