bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hyperbolic temperament and borderline personality disorder
Authors: Hopwood Christopher J. , Thomas Katherine M. , Zanarini Mary C. 
Published: February 2011

ABSTRACTZanarini and Frankenburg described the ‘essential nature’ of borderline psychopathology as involving intense and chronic inner pain deriving from a hyperbolic temperament that is mediated through interpersonal behaviours. These interpersonal behaviours can either provoke kindling events that promote the expression of borderline pathology or buffer against borderline symptoms. This study was designed to test this general hypothesis and to articulate both the temperamental and the mediating constructs implicated in this theory more specifically. A questionnaire containing the elements of this theory was administered to non‐clinical (n = 545), clinical (n = 316) and treatment (n = 50) samples. Covariance analyses supported a hyperbolic temperament factor and four mediating factors labelled as passive, agentic, validation seeking and detached. Overall, validity correlations conformed to predictions in showing a strong association between hyperbolic temperament and borderline and other forms of personality pathology and in demonstrating varying relations between the mediating factors and adaptivity, including psychiatric improvements in a treatment trial. The place of this theoretical model of borderline pathology beside other theories that tend to emphasize personality traits or interpersonal patterns are discussed, and clinical implications of the model are highlighted. Copyright © 2011 John Wiley & Sons, Ltd.
An Approach to Create Silver Containing Antibacterial Coatings by Use of Atmospheric Pressure Plasma Chemical Vapour Deposition (APCVD) and Combustion Chemical Vapour Deposition (CCVD) in an Economic Way
Authors: Zimmermann Roberto , Pfuch Andreas , Horn Kerstin , Weisser Jürgen , Heft Andreas , Röder Michael , Linke Ralf , Schnabelrauch Matthias , Schimanski Arnd 
Published: February 2011

AbstractThe aim of this study was to test the possibilities of using APCVD and CCVD to create effective antibacterial coatings and to determine their antibacterial activity. SiOx‐layers were created by use of a hexamethyldisiloxane (HMDSO) precursor in combination with silver nitrate solution and silver nanoparticles as additives. A strong antibacterial effect of the APCVD and CCVD coated samples on an Escherichia coli (E. coli) strain could be shown. Layers obtained by CCVD showed a longer‐lasting antibacterial activity. The results were verified using a commercially available microbial cell viability assay basing on the measurement of bacterial adenosine triphosphate (ATP) or by counting of colony forming units (CFU) on agar plates. magnified image
Single‐Step Plasma Process Producing Anti‐Reflective and Photovoltaic Behavior on Crystalline Silicon
Authors: Di Mundo Rosa , Ambrico Marianna , Ambrico Paolo Francesco , d'Agostino Riccardo , Italiano Francesca , Palumbo Fabio 
Published: February 2011

AbstractReactive ion etching (RIE) plasma processes fed with CF4 have been investigated as single‐step maskless method for nanotexturing the surface of crystalline silicon. Variation of surface topography under different plasma conditions has been evaluated with scanning electron microscopy and correlated with total, diffuse, and specular reflectance. Chemical features have been evaluated by X‐ray photoelectron spectroscopy and current–voltage characteristics have been measured under dark and illuminated conditions. Results indicate that a widely tunable nanoscale texture can be generated onto silicon surface leading to a reduced total reflectance. A significant uptake of carbon and fluorine is detected onto treated silicon with fluorine mainly in ionic form. Further, the plasma modification is per se capable, without further doping procedures, to generate a photovoltaic behavior onto treated silicon, with higher short circuit current in less reflective samples.
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Development of a brain metastatic canine prostate cancer cell line
Authors: Thudi Nanda K. , Shu Sherry T. , Martin Chelsea K. , Lanigan Lisa G. , Nadella Murali V.P. , Van Bokhoven Adrie , Werbeck Jillian L. , Simmons Jessica K. , Murahari Sridhar , Kisseberth William C. , Breen Matthew , Williams Christina , Chen Ching‐Shih , McCauley Laurie K. , Keller Evan T. , Rosol Thomas J. 
Published: February 2011

AbstractBACKGROUNDProstate cancer in men has a high mortality and morbidity due to metastatic disease. The pathobiology of prostate cancer metastasis is not well understood and cell lines and animal models that recapitulate the complex nature of the disease are needed. Therefore, the goal of the study was to establish and characterize a new prostate cancer line derived from a dog with spontaneous prostate cancer.METHODSA new cell line (Leo) was derived from a dog with spontaneous prostate cancer. Immunohistochemistry and PCR were used to characterize the primary prostate cancer and xenografts in nude mice. Subcutaneous tumor growth and metastases in nude mice were evaluated by bioluminescent imaging, radiography and histopathology. In vitro chemosensitivity of Leo cells to therapeutic agents was measured.RESULTSLeo cells expressed the secretory epithelial cytokeratins (CK)8, 18, and ductal cell marker, CK7. The cell line grew in vitro (over 75 passages) and was tumorigenic in the subcutis of nude mice. Following intracardiac injection, Leo cells metastasized to the brain, spinal cord, bone, and adrenal gland. The incidence of metastases was greatest to the central nervous system (80%) with a lower incidence to bone (20%) and the adrenal glands (16%). In vitro chemosensitivity assays demonstrated that Leo cells were sensitive to Velcade and an HDAC‐42 inhibitor with IC50 concentrations of 1.9 nm and 0.95 µm, respectively.CONCLUSIONThe new prostate cancer cell line (Leo) will be a valuable model to investigate the mechanisms of the brain and bone metastases. Prostate 71:1251–1263, 2011. © 2011 Wiley‐Liss, Inc.
The anti‐interleukin‐6 antibody siltuximab down‐regulates genes implicated in tumorigenesis in prostate cancer patients from a phase I study
Authors: Karkera Jayaprakash , Steiner Hannes , Li Weimin , Skradski Viktor , Moser Patrizia L. , Riethdorf Sabine , Reddy Manjula , Puchalski Thomas , Safer Karim , Prabhakar Uma , Pantel Klaus , Qi Ming , Culig Zoran 
Published: February 2011

AbstractBACKGROUNDInterleukin‐6 (IL‐6) is associated with prostate cancer morbidity. In several experimental models, IL‐6 has been reported to have anti‐apoptotic and pro‐angiogenic effects. Siltuximab (CNTO 328) is a monoclonal anti‐IL‐6 antibody which has been successfully applied in several models representing prostate cancer. This study was designed to assess preliminary safety of siltuximab in patients with early prostate cancer.PATIENTS AND METHODSTwenty patients scheduled to undergo radical prostatectomy received either no drug or siltuximab (6 mg/kg, five patients per group with administration once, two times, and three times prior to surgery). Blood samples were collected for pharmacokinetic and pharmacodynamic analyses. Expression of elements of IL‐6 signaling pathways was analyzed in tumor tissue by immunohistochemistry. Gene analysis in tumor specimens was performed with the DASL array.RESULTSNo adverse events related to siltuximab were observed. Patients treated with siltuximab presented with higher levels of proliferation and apoptosis markers. Following a single dose, serum concentrations of siltuximab declined in a biexponential manner. This study revealed a decrease in phosphorylation of Stat3 and p44/p42 mitogen‐activated protein kinases. In addition, gene expression analyses indicate down‐regulation of genes immediately downstream of the IL‐6 signaling pathway and key enzymes of the androgen signaling pathway.CONCLUSIONSPreliminary safety of siltuximab is favorable. Future studies in which siltuximab could be combined with androgen‐deprivation therapy and experimental therapies in advanced prostate cancer are justified. Prostate 71:1455–1465, 2011. © 2011 Wiley‐Liss, Inc.
Importance of strain for green emitters based on (In, Ga)N films of non‐polar orientation
Authors: Ghosh Sandip , Grahn Holger T. 
Published: February 2011

AbstractWurtzite InxGa1–xN films, with alloy compositions suitable for obtaining green‐light emitting diodes (LED) and lasers in the wavelength range between 520 and 550 nm, experience compressive anisotropic in‐plane strain when grown on non‐polar ($1{\bar {1}}00$) oriented M‐plane or ($11{\bar {2}}0$) oriented A‐plane GaN substrates. The results of calculations of the electronic band structure presented here demonstrate that this strain mixes the valence bands and modifies the emission polarization properties in such a way that lasing characteristics will benefit from it. The advantage improves with partial anisotropic strain relaxation. However, both lasing characteristics and light extraction out of a LED will deteriorate when such a film becomes fully relaxed.
The Central European limited‐area ensemble forecasting system: ALADIN‐LAEF
Authors: Wang Yong , Bellus Martin , Wittmann Christoph , Steinheimer Martin , Weidle Florian , Kann Alexander , Ivatek‐Šahdan Stjepan , Tian Weihong , Ma Xulin , Tascu Simona , Bazile Eric 
Published: February 2011

AbstractThe Central European limited‐area ensemble forecasting system ALADIN‐LAEF (Aire Limitée Adaptation Dynamique Développement InterNational—Limited‐Area Ensemble Forecasting) has been developed within the framework of ALADIN international cooperation and the Regional Cooperation for Limited‐Area modelling in Central Europe (RC LACE). It was put into pre‐operation in March 2007. The main feature of the pre‐operational ALADIN‐LAEF was the dynamical downscaling of the global ensemble forecast from the European Centre for Medium‐range Weather Forecasts (ECMWF). In 2009, ALADIN‐LAEF was upgraded with several methods for dealing with the forecast uncertainties to improve the forecast quality. These are: (1) the blending method, which combines the large‐scale uncertainty generated by ECMWF singular vectors with the small‐scale perturbations resolved by ALADIN breeding into atmospheric initial condition perturbations; (2) the multi‐physics approach, wherein different physics schemes are used for different forecast members to account for model uncertainties; and (3) the non‐cycling surface breeding technique, which generates surface initial condition perturbations.This article illustrates the technical details of the updated ALADIN‐LAEF and investigates its performance. Detailed verification of the upgraded ALADIN‐LAEF and a comparison with its first implementation (dynamical downscaling of ECMWF ensemble forecasts) are presented for a two‐month period in summer 2007. The results show better performance and skill for the upgraded system due to the better representation of forecast uncertainties. Copyright © 2011 Royal Meteorological Society
Timely detection of localized excess influenza activity in Northern California across patient care, prescription, and laboratory data
Authors: Greene Sharon K. , Kulldorff Martin , Huang Jie , Brand Richard J. , Kleinman Kenneth P. , Hsu John , Platt Richard 
Published: February 2011

AbstractTimely detection of clusters of localized influenza activity in excess of background seasonal levels could improve situational awareness for public health officials and health systems. However, no single data type may capture influenza activity with optimal sensitivity, specificity, and timeliness, and it is unknown which data types could be most useful for surveillance. We compared the performance of 10 types of electronic clinical data for timely detection of influenza clusters throughout the 2007/08 influenza season in northern California. Kaiser Permanente Northern California generated zip code‐specific daily episode counts for: influenza‐like illness (ILI) diagnoses in ambulatory care (AC) and emergency departments (ED), both with and without regard to fever; hospital admissions and discharges for pneumonia and influenza; antiviral drugs dispensed (Rx); influenza laboratory tests ordered (Tests); and tests positive for influenza type A (FluA) and type B (FluB). Four credible events of localized excess illness were identified. Prospective surveillance was mimicked within each data stream using a space–time permutation scan statistic, analyzing only data available as of each day, to evaluate the ability and timeliness to detect the credible events. AC without fever and Tests signaled during all four events and, along with Rx, had the most timely signals. FluA had less timely signals. ED, hospitalizations, and FluB did not signal reliably. When fever was included in the ILI definition, signals were either delayed or missed. Although limited to one health plan, location, and year, these results can inform the choice of data streams for public health surveillance of influenza. Copyright © 2010 John Wiley & Sons, Ltd.
The Great Recession of 2008: Impact on the Bangladeshi economy and international business implications
Authors: Ali Muhammad Mahboob , Islam Anisul M. , Wise Victoria J. 
Published: February 2011

AbstractThis article examines the current global financial crisis (GFC) and its impact on Bangladesh's economy and discusses international business implications for the country within an institution‐based analytical framework. The article finds that the macroeconomy of Bangladesh has shown remarkable resilience in the face of this massive global crisis, and the impact has been minimal and limited to a moderate slowdown of the economy The country thus could be poised for taking advantage of international business opportunities as the global economy begins to recover. Further, JPMorgan's Frontier Five and Goldman Sachs's Next Eleven classification of Bangladesh indicates enormous potential for growth and development. The article suggests that the Bangladeshi diaspora could serve as a connecting hub so that “brain gain” could be achieved through labor migration and remittances. Strategic alliances among home and foreign firms are also important to the future capacity building of the country. However, strategic management in the form of further institutional, structural, and policy reforms are critical in enabling the country to develop an international‐business‐friendly environment conducive to taking advantage of evolving global opportunities and realizing its full potential. © 2011 Wiley Periodicals, Inc.
Über anorganische Verbindungen des Stickoxyds. VII: Über die Bildung von Nitrosylcyanokomplexen durch eine neuartige Disproportionierungsreaktion des Hydroxylamins
Authors: Hieber W. , Nast R. , Proeschel E. 
Published: February 2011

AbstractIn einer Reihe von Fällen konnte gezeigt werden, daβ sich Hydroxylamin zur Einführung von Stickoxyd in Komplexe eignet, wobei Disproportionierung gemäβstattfindet. So führt die Reaktion von Kaliumtetracyanoniccolat(II) mit Hydroxylamin zur violetten Lösung des Nitrosylkomplexes K2[Ni(CN)3NO], dessen Identifizierung mit der zuvor präparativ isolierten Verbindung auf optischem Wege gelang. Wesentlich für den Eintritt der Reaktion ist das Vorliegen eines Zentralatoms mit 16 Elektronen auf dem 3d‐4sp‐Niveau, wodurch die energetisch stark positive Umlagerung des Nitrosokomplexes zum Nitrosylkomplex und Erreichung des Bindungszustandes des Nickelcarbonyls ermöglicht ist.Unter diesem Gesichtspunkt wurde tatsächlich auch die Darstellung des Mangan‐Nitrosylkomplexes K3[Mn(CN)5NO] aus dem K3[Mn(CN)6] mit Hilfe von Hydroxylamin durchgeführt; desgleichen erklärt sich so letzten Endes die kompliziertere Bildung des Na2[Fe(CN)5NO] aus den Cyankomplexen des Eisens.Man erhält die Reihe der Nitroprussiatein denen sich die Zentralatome im Bindungszustand der monomeren Carbonyle befinden und deren Liganden oktaedrisch bzw tetraedrisch angeordnet sind; die auβerordentliche Stabilität dieser Elektronenzustände erklärt das enorme Bildungsbestreben dieser Verbindungen.
Diffusion‐weighted Magnetic Resonance Imaging for Detecting Lymph Node Metastasis of Rectal Cancer
Authors: Mizukami Yo , Ueda Shugo , Mizumoto Akiyoshi , Sasada Tetsuro , Okumura Ryosuke , Kohno Shigene , Takabayashi Arimichi 
Published: February 2011

AbstractBackgroundPreoperative diagnosis of lymph node metastasis is important in determining the optimal therapy for rectal cancer. It has been shown that diffusion‐weighted magnetic resonance imaging (DWI) is a useful tool for detecting malignant tumors.MethodsOne hundred twenty‐nine consecutive patients with rectal cancer were examined with DWI + conventional (T1‐weighted and T2‐weighted) MRI and computed tomography (CT). All 129 patients underwent rectal resection with total mesorectal excision. Findings on DWI + conventional MRI and CT were compared with those from histopathologic examinations.ResultsFifty‐nine (46%) patients had metastatic lymph nodes on histopathologic examinations. Two hundred twenty (18%) of 1,250 lymph nodes were pathologically positive for tumor metastasis. The overall patient‐based sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of DWI + conventional MRI were 93, 81, 81, 93, and 87%, respectively. Corresponding values of CT were 73, 79, 74, 77, and 76%, respectively. The overall node‐based sensitivity, specificity, PPV, NPV, and accuracy of DWI + conventional MRI were 97, 81, 52, 99, and 84%, respectively. Corresponding values of CT were 86, 80, 48, 96, and 81%, respectively.ConclusionDWI + conventional MRI is effective for the detection of lymph node metastasis and useful for selection of the optimal therapy for rectal cancer.
Noninfectious Wound Complications in Clean Surgery: Epidemiology, Risk Factors, and Association with Antibiotic Use
Authors: Uçkay Ilker , Agostinho Americo , Belaieff Wilson , Toutous‐Trellu Laurence , Scherer‐Pietramaggiori Saja , Andres Axel , Bernard Louis , Vuagnat Hubert , Hoffmeyer Pierre , Wyssa Blaise 
Published: February 2011

AbstractBackgroundNoninfectious wound complications are frequent and often are confused with and treated as infection.MethodsWe assessed the epidemiology, impact, risk factors, and associations with antibiotic use of noninfectious wound complications in clean orthopedic and trauma surgery. We report a single‐center, prospective, observational study in an orthopedic department.ResultsAmong 1,073 adult patients, 630 (59%) revealed clinically relevant postoperative noninfectious wound complications, leading to a significant prolongation of hospital stay (14 vs. 12 days; Wilcoxon rank‐sum test; p < 0.02) compared with patients without complications. The most frequent and severe complications were discharge with dehiscence (n = 437; 41%) and hematoma (n = 379; 35%). Forty‐seven patients (47/630; 7%) underwent reoperation for dehiscence (n = 39) or hematoma (n = 8). These patients made up 4.3% of the entire study population (47/1,073). In multivariate analysis, an ASA score ≥2 points, age ≥ 60 years, surgery duration for ≥90 min, implant‐related surgery, and poor compliance toward nurses’ recommendations were pronounced risk factors for these complications, whereas antibiotic‐related parameters had no influence. Staple use was significantly associated with wound discharge but not with hematoma.ConclusionsWound complications, such as dehiscence with discharge or hematoma after clean orthopedic and trauma surgery, are frequent with an overall incidence of 60%. Although they lead to few surgical reinterventions, they prolong hospital stay by 2 days. Few clinical parameters show association with wound complications. Among them, improvements of patient compliance and avoidance of staples use for skin closure are the most promising actions to decrease complication risk.
Seasonal variability in survivorship of a cooperatively breeding tropical passerine
Authors: Sankamethawee Wangworn , Pierce Andrew J. , Hardesty Britta Denise , Gale George A. 
Published: February 2011

AbstractSurvival of tropical passerines is thought to be higher than those in northern temperate regions, but relatively few tropical studies have addressed this issue, particularly in tropical Asia. We examined factors that may have influenced the survival rate of a cooperatively breeding bird, the puff‐throated bulbul (Alophoixus pallidus), in an evergreen forest in northeastern Thailand. These factors included year, season (breeding and non‐breeding), sex, and presence of helper(s) in a family group. We present evidence of breeding season‐dependent survival in a tropical passerine using an information theoretic approach based on both mark‐recapture and resighting data collected during 6 years of study. Based on colour‐banded adults the annual survival rate did not vary significantly among years (average = 0.85 ± 0.02 SE). The mean lifespan (MLS) for the population was 6.22 ± 4.38 SE years. Survivorship was lower during the breeding season (0.89 ± 0.02 SE) than during the non‐breeding season (0.96 ± 0.02 SE). The MLS of males and females was 6.70 ± 7.73 SE and 5.87 ± 4.88 SE years, respectively. The annual survival rate we observed was high compared to the estimates of other tropical and temperate passerines, possibly due to the relatively stable climatic conditions in tropical latitudes and puff‐throated bulbuls being generalists that exploit a wide range of food resources both in space and time.
Influence of the prey aphid Uroleucon nigrotuberculatum parasitizing Solidago canadensis on the larval and adult survivorship of the predatory ladybird beetle Harmonia axyridis
Authors: Kamo Tsunashi , Tokuoka Yoshinori 
Published: February 2011

AbstractThe ladybird beetle Harmonia axyridis is an aphidophagous natural enemy in Japan. The alien plant Solidago canadensis is widespread in Japanese agricultural landscapes, and the alien aphid Uroleucon nigrotuberculatum parasitizes the plant. We examined the quality of the aphid as food for all developmental stages of H. axyridis. First‐instar larvae fed the aphid died within 2 days. Larvae at later developmental stages survived for significantly longer periods but died before pupation. Adults fed the aphid also died within 10 days. These results suggest that U. nigrotuberculatum parasitizing S. canadensis is unsuitable for H. axyridis during the beetle's entire life cycle.