bluuebunny/crossref_metadata_2025_split huggingface dataset:
Natural elicitors enhanced suberin polyphenolic accumulation in wounded potato tuber tissues
Authors: Dogramaci Munevver , Sarkar Dipayan , Finger Fernando L. , Shetty Kalidas , Fugate Karen K. 
Published: May 2024

IntroductionUnintended wounding or bruising during harvest or postharvest handling leads to significant tuber loss and imposes economic burden to potato industry. Therefore, finding effective strategies to mitigate wound-related tuber losses is very important from industry perspectives. Formation of protective barrier through accumulation of suberin polyphenolics (SPP) is a natural and initial response of potato tuber tissues to wounding.Materials and methodsIn this study, efficacy of two natural elicitors, such as chitosan oligosaccharide (COS 0.125 g L-1) and cranberry pomace residue (Nutri-Cran 0.125 g L-1) was investigated using a mechanically wounded tuber tissue model and by histological determination of SPP formation in five agronomically relevant and red-skin potato cultivars (Chieftain, Dakota Rose, Dakota Ruby, Red LaSoda, Red Norland). Furthermore, the potential role of stress protective metabolic regulation involving phenolic metabolites, proline, and antioxidant enzymes in tuber WH processes were also investigated during 0-9 days after wounding.Results and discussionExogenous treatments of both COS and Nutri-Cran resulted into enhanced SPP formation in wounded surface, but the impact was more rapid with Nutri-Cran treatment in select cultivars. Greater contents of total soluble phenolic, ferulic acid, chlorogenic acid, total antioxidant activity, and superoxide dismutase activity were also observed in elicitor treated tuber tissues at different time points after wounding. Nutri-Cran treatment also reduced the activity of succinate dehydrogenase in Red Norland and Dakota Ruby at 3 d, indicating a suppression in respiration rate. Collectively, these results suggest that Nutri-Cran can be potentially utilized as an effective WH treatment to potato tubers for minimizing wound-related losses.
“Finding my voice again” - women’s experiences of psychological therapy in perinatal secondary care settings: a qualitative study
Authors: O’Brien Jayne , Gregg Lynsey , Wittkowski Anja 
Published: May 2024

IntroductionAlthough women often experience mental health comorbidities in the perinatal period, the evidence-base for psychological therapy across diagnostic boundaries in the perinatal period remains limited. As there is a need to understand experiences of therapy, irrespective of diagnosis, to inform intervention provision, the aims of this study were to explore women’s experiences of psychological therapy for perinatal mental health difficulties and to identify the mechanisms that women attributed to the most significant therapeutic change for themselves and/or the mother-infant relationship.MethodSemi-structured interviews were conducted with 16 women who received therapy within specialist perinatal community mental health settings in the Northwest of England, the UK. Interview data were analysed using reflexive thematic analysis.ResultsOne overarching theme entitled participant life stories were at the heart of therapy was identified alongside three other main themes: 1.) We’re in this together – therapeutic bond and establishing a coherent sense of self, 2.) Surfing the urge to ‘fix’ feelings – Sitting with emotions improved regulation and 3.) Seeing myself in a new light – Shifting self-blame to self-compassion enhanced self-efficacy. Theme 1 consisted of three subthemes. Participants described the quality of the therapeutic relationship as the fundamental foundation to (re)connecting with their needs, values and boundaries, which improved their sense of agency, self-esteem, therapeutic engagement and self-understanding. Shifting emotional avoidance to emotional engagement improved their self-regulation. Considering alternative factors that could have contributed to their experiences helped them to defuse self-blame and enhance self-compassion. Finally, changes in their mental health led to positive relational changes in their relationship with their infant and improved communication with partners.DiscussionSensitivity, engagement and responsivity experienced in the therapist-woman relationship was reported to be mirrored in the mother-infant relationship. Developing a coherent sense of self and self-regulation skills both appeared to heighten women’s self-compassion and empathy for their infants, which also seemed to improve their ability to tolerate uncertainty and mixed emotions within themselves and their infants. The mechanisms of change in the perinatal period are important to consider at a stakeholder, therapist and service management level to parsimoniously and best meet the needs of women and the mother-infant relationship.
Placebo effects of repetitive transcranial magnetic stimulation on negative symptoms and cognition in patients with schizophrenia spectrum disorders: a systematic review and meta-analysis
Authors: Wang Mingqi , Lu Shensen , Hao Lu , Xia Yifei , Shi Zhenchun , Su Lei 
Published: May 2024

BackgroundNegative symptoms and cognitive impairments are highly frequent in schizophrenia spectrum disorders (SSD), associated with adverse functional outcomes and quality of life. Repetitive transcranial magnetic stimulation (rTMS) has been considered a promising therapeutic option in SSD. However, placebo effects of rTMS on these symptoms remained unclear.ObjectiveTo investigate placebo effects of rTMS on alleviating negative symptoms and cognitive impairment in patients with SSD and to explore potential moderators.MethodsWe systematically searched five electronic databases up to 15 July 2023. Randomized, double-blind, sham-controlled trials investigating effects of rTMS on negative symptoms or cognition in patients with SSD were included. The pooled placebo effect sizes, represented by Hedges’ g, were estimated using the random-effects model. Potential moderators were explored through subgroup analysis and meta-regression.ResultsForty-four randomized controlled trials with 961 patients (mean age 37.53 years; 28.1% female) in the sham group were included. Significant low-to-moderate pooled placebo effect sizes were observed for negative symptoms (g=0.44, p&lt;0.001), memory (g=0.31, p=0.010), executive function (g=0.35, p&lt;0.001), working memory (g=0.26, p=0.004), and processing speed (g=0.36, p=0.004). Subgroup analysis indicated that placebo effects were affected by sham stimulation methods, rTMS targeting approaches, and stimulation frequency.ConclusionsPlacebo effects of rTMS on negative symptoms and cognition in patients with SSD are significant in a small-to-moderate magnitude, which might be mediated by rTMS parameters. Our findings will provide new insights for practitioners to further optimize and establish standardized rTMS protocols for future RCTs tackling cardinal symptoms in SSD.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023390138.
Suicidal behavior and associated factors among holy water users at Northwest, Ethiopia, 2023: an institution based cross-sectional study
Authors: Kassahun Gedefaw Tegegne , Addis Fikir , Mossie Tilahun Belete , Belete Habte , Munie Birhanu Mengist 
Published: May 2024

BackgroundSuicide is a serious cause of mortality that affects families, communities, and the entire country. Because of a lack of national systematic reporting for cause-specific mortality, a high level of stigma, and religious non-acceptance, suicidal behavior is an under-reported and concealed cause of death in the majority of low- and middle-income countries.ObjectiveThe aim of this study was to assess the prevalence of suicidal behavior and associated factors among holy water users at the Andassa Saint George Monastery, 2023.MethodsAn institution-based cross-sectional study was conducted at the Andassa Saint George Monastery from 5 April to 5 May 2023. A systematic random sampling method was utilized to select 423 study participants and the Suicidal Behaviors Questionnaire—Revised was used to assess suicidal behavior. The data were gathered using the epicollect5 software with a face-to-face interview method then exported to SPSS-25 for analysis. A binary logistic regression model was used and all variables in a bivariate analysis with a p-value of less than 0.25 were entered into a multivariable logistic regression model, and statistical significance was declared at a p-value of less than 0.05.ResultsThe prevalence of suicidal behavior among holy water users was 9.7% (95% CI: 7.1–12.4). Being female [2.632 (1.206–5.748)], living alone [2.52 (1.06–5.97)], and having depression [3.03 (1.32–6.99)], epilepsy [3.82 (1.28–11.40)], and diabetes mellitus [3.37 (1.229–9.25)] were significantly associated with suicidal behavior.ConclusionIn this study, almost 1 in 10 had engaged in suicidal behavior in their lifetime. Several risk factors for suicidal behavior were identified, including being female, living alone, and having diabetes mellitus, epilepsy, and depression.
Exploring the relationship between smoking and poor sleep quality: a cross-sectional study using NHANES
Authors: Sun Haoxiong , Li Sijia 
Published: May 2024

IntroductionSleeping disorders is a high prevalent disorder, and although previous research has suggested a link between smoking and sleep disorders, there is a lack of large-scale, nationally representative studies examining this association across multiple sleep outcomes and exploring dose-response relationships.MethodsThis study used data from 30,269 participants from the NHANES database (2007–2020). Weighted logistic regression models were used to assess the associations between smoking status (non-smoker, light smoker, moderate smoker, and heavy smoker) and various sleep outcomes, including insufficient sleep duration, reported sleep problems, snoring, snorting, or stopping breathing during sleep, and daytime sleepiness. Dose-response relationships were explored using restricted cubic splines.ResultsCompared to non-smokers, heavy smokers had significantly higher odds of experiencing insufficient sleep duration with OR 1.732 (95% CI 1.528–1.963, P &lt;0.001), reported sleep problems with OR 1.990 (95% CI 1.766–2.243, P &lt;0.001), occasional or frequent snoring with OR 1.908 (95% CI 1.164–3.128, P = 0.03), and occasional or frequent snorting or stopping breathing during sleep with OR 1.863 (95% CI 1.183–2.936, P = 0.022), while results for sometimes, often or almost always being overly sleepy during the day with OR 1.257 (95% CI 0.872–1.810, P = 0.115) are not significant. A trend of positive correlation was observed between smoking and all sleep disorder outcomes (P for trend &lt; 0.05). Dose-response analyses revealed that the odds of these sleep outcomes increased with higher smoking levels.ConclusionSmoking is significantly associated with various sleep disorders, and a dose-response relationship exists between smoking levels and the odds of experiencing these sleep problems. These findings underscore the importance of addressing smoking as a modifiable risk factor for poor sleep health and suggest that reducing smoking, even if complete cessation is not achieved, may have positive effects on sleep outcomes.
Enhancement of single-lead dry-electrode ECG through wavelet denoising
Authors: Abdou Abdelrahman , Krishnan Sridhar 
Published: May 2024

Neonatal electrocardiogram (ECG) monitoring is an important diagnostic tool for identifying cardiac issues in infants at birth. Long-term remote neonatal dry-electrode ECG monitoring solutions can be an additional step for preventive healthcare measures. In these solutions, power and computationally efficient embedded signal processing techniques for denoising newborn ECGs can assist in increasing neonatal medical wearable time. Wavelet denoising is an appropriate denoising mechanism with low computational complexity that can be implemented on embedded microcontrollers for long-term remote ECG monitoring. Discrete wavelet transform (DWT) denoising for neonatal dry-electrode ECG using different wavelet families is investigated. The wavelet families and mother wavelets used include Daubechies (db1, db2, db3, db4, and db6), symlets (sym5), and coiflets (coif5). Different levels of added white Gaussian noise (AWGN) were added to 19 newborn ECG signals, and denoising was performed to select the appropriate wavelets for neonatal dry-electrode ECG. The selected wavelets then undergo real noise additions of baseline wander and electrode motion to determine their robustness and accuracy. Signal-to-noise ratio (SNR), mean squared error (MSE), and power spectral density (PSD) are used to examine denoising performance. db1, db2, and db3 wavelets are eliminated from analysis where the 30 dB AWGN led to negative SNR improvement for at least one newborn ECG, removing important ECG information. db4 and sym5 are eliminated from selection due to their different waveform morphology compared to the dry-electrode newborn ECG’s QRS complex. db6 and coif5 are selected due to their highest SNR improvement and lowest MSE of 6.26 × 10−6 and 1.65 × 10−7 compared to other wavelets, respectively. Their wavelet shapes are more like a newborn ECG’s QRS morphology, validating their selection. db6 and coif5 showed similar denoising performance, decreasing electrode motion and baseline wander noisy ECG signals by 10 dB and 14 dB, respectively. Further denoising of inherent dry-electrode noise is observed. DWT with coif5 or db6 wavelets is appropriate for denoising newborn dry-electrode ECGs for long-term neonatal dry-electrode ECG monitoring solutions under different noise types. Their similarity to newborn dry-electrode ECGs yields accurate and robust reconstructed denoised newborn dry-electrode ECG signals.
Modulation of cyclophosphamide-induced immunosuppression and intestinal flora in broiler by deep eutectic solvent extracted polysaccharides of Acanthopanax senticosus
Authors: Su Jianqing , Xue Jiaojiao , Wang Xueyan , Zhang Rui , Zhang Xueping , Yang Yaosen , Chu Xiuling 
Published: May 2024

IntroductionThe aim of this experiment was to investigate the modulation effect of Acanthopanax senticosus polysaccharide (ASPS-PD) extracted with deep eutectic solvent on cyclophosphamide-induced immunosuppression in broilers and its modulation of the gut microbiota of broilers.MethodsThe 108 one-day-old broilers were divided into six groups, including the control group, the Cyclophosphamide (CY) model group, the ASPS-PD control group, the ASPA-PD high and low dose groups and the Astragalus polysaccharide group. Body weight, feed intake, feed conversion ratio, and immune organ index of broilers at 7, 14, and 21 days were determined; IL-2, IFN-γ, and lgG1 levels were determined by enzyme-linked immunosorbent assay (ELISA); Broiler caeca feces were analyzed by amplification and 16S rRNA sequencing.ResultsThe results showed that ASPS-PD can restore growth performance, increase immune organ index and improve serum cytokine levels of IL-2 and IFN-γ and immunoglobulin lgG1 levels in CY-treated broilers. The analysis of cecum flora showed that ASPS-PD can promote the proliferation of beneficial bacteria and reduce the number of harmful bacteria, regulating intestinal flora.DiscussionTherefore, ASPA-PD may be a potential novel immunomodulator to ameliorate CY-induced immunosuppression and intestinal flora dysregulation in broiler.
Developing a Novel Murine Meningococcal Meningitis Model Using a Capsule-Null Bacterial Strain
Authors: Caracoti Viorela-I. , Caracoti Costin-Ș. , Ancuța Diana L. , Ioniță Fabiola , Muntean Andrei-A. , Bhide Mangesh , Popa Gabriela L. , Popa Mircea I. , Coman Cristin 
Published: May 2024

Background: Neisseria meningitidis (meningococcus) is a Gram-negative bacterium that colonises the nasopharynx of about 10% of the healthy human population. Under certain conditions, it spreads into the body, causing infections with high morbidity and mortality rates. Although the capsule is the key virulence factor, unencapsulated strains have proved to possess significant clinical implications as well. Meningococcal meningitis is a primarily human infection, with limited animal models that are dependent on a variety of parameters such as bacterial virulence and mouse strain. In this study, we aimed to develop a murine Neisseria meningitidis meningitis model to be used in the study of various antimicrobial compounds. Method: We used a capsule-deficient Neisseria meningitidis strain that was thoroughly analysed through various methods. The bacterial strain was incubated for 48 h in brain–heart infusion (BHI) broth before being concentrated and injected intracisternally to bypass the blood–brain barrier in CD-1 mice. This prolonged incubation time was a key factor in increasing the virulence of the bacterial strain. A total of three more differently prepared inoculums were tested to further solidify the importance of the protocol (a 24-h incubated inoculum, a diluted inoculum, and an inactivated inoculum). Antibiotic treatment groups were also established. The clinical parameters and number of deaths were recorded over a period of 5 days, and comatose mice with no chance of recovery were euthanised. Results: The bacterial strain was confirmed to have no capsule but was found to harbour a total of 56 genes coding virulence factors, and its antibiotic susceptibility was established. Meningitis was confirmed through positive tissue culture and histological evaluation, where specific lesions were observed, such as perivascular sheaths with inflammatory infiltrate. In the treatment groups, survival rates were significantly higher (up to 81.25% in one of the treatment groups compared to 18.75% in the control group). Conclusion: We managed to successfully develop a cost-efficient murine (using simple CD-1 mice instead of expensive transgenic mice) meningococcal meningitis model using an unencapsulated strain with a novel method of preparation.
A selective separation method for microplastics using ultrasonic jet atomization
Authors: Matsuura Hiroshi , Furukawa Hiromitsu , Kondo Atsushi , Kurita Hiroki , Toyoshi Takuya , Watanabe Yoshinori , Tanikawa Tamio , Hashimoto Hideki 
Published: May 2024

Abstract
This paper reveals that ultrasonic jet atomization using a diaphragm enables the enclosure of microplastics in water into atomized mist, emitting them into the air. In particular, a strong correlation is found between the sizes of the atomized mist and the acrylic particles enclosed in the mist: Acrylic particles with an average diameter of 1.5 μm or smaller are selectively enclosed within the atomized mist with an average diameter of 2.2 μm. This result indicates that jet atomization has the ability to select particles with diameters of 1.5 μm or less from numerous micro-particles with different diameters and separate them into individual particles without aggregation. The results of this study can be applicable to the process of analyzing microplastics dispersed in rivers, lakes, and oceans for separating particles of a targeted diameter from numerous particles of different diameters without aggregation.
الخروج على عباءة الرواد!
Authors: د. هشام فاضل محمود  
Published: May 2024

لا يستطيع اي مهتم بشؤون الادب ان ينكر الانجاز الشعري الكبير الذي حققه الرواد ( السياب ونازك الملائكة ) واسهامهم الثرة في رفد الحركة الشعرية الجديدة وتاثيرهم الخلاق في اجيال متواترة من الشعراء .
التوسع الحضري لمدينة بغداد وأثره على الأراضي الزراعية
Authors: أ.م. سوسن صبيح حمدان  , م.م حنان حسين دريول  
Published: May 2024

تناول البحث دراسة التوسع الحضري لمدينة بغداد من خلال تسليط الضوءعلى المحيط الحضـري لمديـنة بغــداد على اقليـمها الزراعي وبيان مخاطـر زحف الاستـخدام السكني علـى الاراضي الزراعية او الصالحة للزراعة مما يترك اثارا سلبية عديدة ياتي في مقدمتها انخفاض الانـتاج الزراعي وتدمـيرمساحات واسعة من الاراضي الصـالحة للزراعة فضلا عـن التدهـور الـبيـئي وارتفـاع معدلات الـتـلوث وتدنـي الكفـاءة الوظيفـية للخدمات العامـة وخدمـات البنـى الارتكازية وافتقار العديد من المناطق السكنية لاسيما العشوائية منها الى هذه الخدمات.
El presente de subjuntivo en español y la traducción de sus estructuras al árabe
Authors: م.م.محمد هاشم محيسن  , م.م.امل طه محمد امين  
Published: May 2024

لكل لغة حالات إعرابية خاصة تميزها عن بقية اللغات فاللغة الاسبانية لديها ثلاث حالات خاصة بالفعل فقط وهي الحالة الدليلية ويقابلها في العربية حالة الرفع والحالة غير الدليلية التي تشير الى احداث غير مؤكدة ويقابلها بالعربية حالة النصب اما الحالة الثالثة هي حالة الامر ويقابلها الامر في لغتنا العربية.
في هذه الدراسة تناولنا المضارع المنصوب في اللغة الاسبانية وبيان تراكيبه القواعدية وترجمتها مقارنة مع المضارع المنصوب في اللغة العربية .في اللغة الاسبانية يصبح الفعل المضارع منصوبا في الحالات الاتية:

اذا جاء في جملة ثانوية تسبقها جملة رئيسة في زمن المضارع ايضا او المستقبل وفعلها يدل على رغبة او شعور او نصيحة...الخ.على سبيل المثال:

Quiero que estudies mucho. تدرس كثيرا . أرِيدُ أنْ

ثمة تراكيب قواعدية خاصة تجعل المضارع منصوبا .

الفعل في حالة الامر المثبت (بالنسبة للضمائر الشخصية :حضرتك وحضراتكم للمذكر والمؤنث) وفي حالة الامر المنفي (بالنسبة للضمائر الشخصية انت و انتم حضرتك وحضراتكم للمذكر والمؤنث).
اثر تصميم تعليمي قائم على ستراتيجية "M.U.R.D.E.R" المعدلة لمساعدات التذكر في تحصيل مادة الرياضيات لدى طالبات الصف الرابع العلمي
Authors: أ.د. رافد بحر احمد المعيوف  , م.م. سهاد عبد النبي سلمان صحو  
Published: May 2024

هدف البحث الحالي تعرف أثر التصميم التعليمي المقترح القائم على ستراتيجية M.U.R.D.E.R المعدلة لمساعدات التذكر في تحصيل مادة الرياضيات لدى طالبات الصف الرابع العلمي وتحقيقاً لهدف البحث أُعتمد منهج البحث التجريبي، وإستخدم فيه التصميم التجريبي الحقيقي ذي المجموعتين المتكافئتين ذا الاختبار البعدي لقياس التحصيل، ووضعت الفرضية الصفرية الآتية :
"لايوجد فرق ذو دلالة احصائية عند مستوى الدلالة (0.05) بين متوسطي درجات طالبات المجموعة التجريبية اللاتي درسن المادة المقررة بالتصميم التعليمي وفقاً لستراتيجية M.U.R.D.E.R المعدلة وبين طالبات المجموعة الضابطة اللاتي درسن المادة نفسها على وفق الطريقة الاعتيادية في اختبار التحصيل".
وتحدد مجتمع البحث بطالبات الصف الرابع العلمي في المدارس الثانوية والاعدادية النهارية التابعة للمديرية العامة لتربية بغداد/ الرصافة الثانية، وبالاختيار العشوائي تم اختيار ثانوية سومر للبنات لتكون ميداناً لإجراء البحث، ومن بين شعبها الثلاثة لطالبات الصف الرابع العلمي تم اختيار شعبتين عشوائيا لتمثل عينة البحث، وبشكل عشوائي ايضا تم تحديد المجموعة التجريبية التي بلغ عددها (37) طالبة والتي دُرست وفقا لستراتيجية M.U.R.D.E.R المعدلة، اما المجموعة الضابطة التي دُرست وفق الطريقة الإعتيادية. وبهذا بلغ عدد طالبات عينة البحث (72) طالبة، وتم إجراء التكافؤ بين مجموعتي البحث في المتغيرات (العمر الزمني، التحصيل السابق لمادة الرياضيات، الذكاء، اختبار المتطلبات السابقة) ولغرض تحقيق اهداف وجمع البيانات الخاصة بالتجربة تم بناء إختبار تحصيل تكون بصيغته النهائية من (40) فقرة موضوعية من نوع الاختيار من متعدد، وبعد التثبت من صدق الاختبار بعد عرضه على مجموعة من الخبراء والمحكمين، تم تطبيقه على عينة استطلاعية تم التحقق من خلالها من وضوح فقرات الاختبار وتعليماته وتحديد زمن الاختباروأجراء التحليلات الإحصائية المناسبة، والتأكد من الخصائص السايكومترية للإختبار والتي بموجبها اصبح الاختبار جاهزا لتطبيقه على مجموعتي البحث.
وبعد تطبيق الاختبار على مجموعتي البحث تم تحليل نتائجه بإستخدام الأدوات الإحصائية المناسبة مثل معامل إرتباط بيرسون ومعادلة كيودر ريتشاردسون-20 ، واختبار (t-test) لعينتين مستقلتين وقد أشارت النتائج إلى وجود فرق دال ذو دلالة أحصائية لصالح طالبات المجموعة التجريبية التي دُرست بالتصميم التعليمي وفقاً لستراتيجية M.U.R.D.E.R المعدلة في التحصيل وبين طالبات المجموعة الضابطة التي دُرست وفق الطريقة الاعتيادية، وفي ضوء النتائج صيغت عدد من الاستنتاجات منها، ان تدريس طالبات الرابع العلمي بالتصميم التعليمي وفقاً لستراتيجية M.U.R.D.E.R المعدلة كان له أثر ايجابي في تحصيلهم الدراسي، والتي في ضوئها وضعت عدد من التوصيات مثل حث المدرسين على تهيئة بيئة تعليمية مناسبة تتوافر فيها كافة متطلبات نجاح العملية التعليمية من عملية تخطيط ووضع الاهداف من خلال تعرفهم على خطوات بناء التصاميم التعليمية عن طريق عقد ندوات ودورات في هذا المجال، وتم اقتراح عدد من الدراسات مثل إجراء دراسات مماثلة على مراحل تعليمية مختلفة، اجراء دراسة للتعرف على اثر التصميم التعليمي وفق ستراتيجية M.U.R.D.E.R المعدلة في متغيرات تابعة اخرى كالدافع المعرفي، القلق في الرياضيات، الميل نحو الرياضيات..... وغيرها.