bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mathematics teachers in the time of digital technologies: a theoretical framework adapting the double approach to study their activity
Authors: Abboud Maha 
Published: May 2024

Article à paraître dans un numéro spécial de la revue Recherches en Didactique des Mathématiques
This text deals with the mathematics teacher’s activity in digital technologies-based sessions. It is composed of two parts. The first part outlines recent studies and theoretical models that have been developed to study the teaching dimension in learning and teaching within environments integrating these technologies. The second presents a theoretical framework for the study of the teacher's activity in ordinary classroom situations: the DAaT (Double Approach applied to Technology). This framework is derived from the Double Didactic and Ergonomic Approach (Robert and Rogalski, 2002) while introducing adaptations and adding complementary constructs in order to better consider the specificity of the studied environments. The theoretical concepts thus developed are presented and discussed. The conclusion returns to the usefulness of the theoretical and methodological tools provided by the research in this field for the enrichment of teacher practices or for teacher education
Ce texte porte sur l’activité de l'enseignant de mathématiques utilisant des technologies numériques. Il est composé de deux parties. La première esquisse un panorama des études récentes et des modèles théoriques qui ont été développés pour étudier la dimension enseignante dans des environnements d’apprentissage et d’enseignement intégrant ces technologies. La deuxième présente un cadre théorique pour l’étude de l’activité de l’enseignant dans des situations ordinaires de classe : la DAaT (Double Approche adaptée aux Technologies). Ce cadre prend appui sur la Double Approche didactique et ergonomique des pratiques (Robert et Rogalski, 2002) tout en y introduisant des adaptations et y apportant des compléments et des prolongements afin de rendre compte de la spécificité des environnements étudiés. Les concepts théoriques ainsi développés sont présentés et discutés. La conclusion revient sur l’utilité des outils et résultats issus de la recherche dans ce domaine pour l’enrichissement des pratiques ou pour leur formation
Inclusão da Classificação Internacional de Funcionalidade, Incapacidade e Saúde nos projetos pedagógicos de cursos de graduação em Fisioterapia e Terapia Ocupacional de Universidades Federais Brasileiras
Authors: De Oliveira Huryel Tarcio , Rodrigues Gleyson Hiego Vieira , Rocha Tainara Davidis , Fangel Renan , Fangel Leticia Meda Vendrusculo 
Published: May 2024

Introdução: A Fisioterapia e a Terapia Ocupacional têm um olhar voltado para a funcionalidade do indivíduo na sua prática profissional. A funcionalidade e a incapacidade são descritas pela Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF), que deve ser utilizada interdisciplinarmente. O uso da CIF por fisioterapeutas e terapeutas ocupacionais é garantido por legislações brasileiras, que também recomendam às Instituições de Ensino Superior o ensino da CIF nos cursos de graduação, pós-graduação e extensão em Fisioterapia e Terapia Ocupacional. Objetivo: Identificar a inserção da CIF nos projetos pedagógicos (PPCs) dos cursos de fisioterapia e terapia ocupacional de Universidades Federais brasileiras. Método: Pesquisa documental e exploratória dividida em duas etapas, sendo elas identificação dos cursos e extração de dados dos PPCs. Resultados: Foram analisados 39 PPCs considerando os dois cursos. 22 PPCs incluíram o termo funcionalidade ou a CIF em ao menos 1 dos três tópicos analisados, o correspondente a cerca de 56% dos PPCs incluídos neste estudo. Conclusão: A CIF ainda é pouco inserida nos PPCs dos cursos de Fisioterapia (66%) e de Terapia Ocupacional (50%) de Universidades Federais brasileiras, fazendo-se necessária a inserção desse componente curricular para formar profissionais com um olhar abrangente em relação à saúde da população, e além disso, se adequarem às novas proposições de Diretrizes Curriculares Nacionais. É preciso também que pesquisadores estudem e aprofundem suas análises acerca do modelo biopsicossocial, para que assim possam propor métodos de suprimento ao déficit de conhecimento atual sobre a CIF por terapeutas ocupacionais e fisioterapeutas.
Vivência acadêmica e saúde mental de estudantes de Terapia Ocupacional
Authors: Neto de Menezes Camargo Campos Roberta Liz , Oliveira Adrielly Pereira , Matsukura Thelma Simões , Constantinidis Teresinha Cid 
Published: May 2024

Introdução: A saúde mental de estudantes universitários tem sido alvo de preocupação social em decorrência da elevada prevalência de transtornos mentais entre este grupo. Além de alto índice de reprovação, trancamento e evasão universitária, verifica-se estresse, ansiedade, depressão, drogadição, suicídio entre esses jovens. Objetivo: compreender a vivência acadêmica de estudantes de terapia ocupacional e identificar conteúdos e práticas do curso que afetam a saúde mental, na perspectiva dos estudantes do curso. Método: participaram 25 estudantes de diferentes universidades e períodos do curso de terapia ocupacional. Foram realizadas sessões de grupo focal, que foram transcritas e analisadas por meio do software IRAMUTEQ (Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires). Resultado: foi identificado que o sofrimento psíquico vivenciado por esse grupo está relacionado à densidade de conteúdo nas disciplinas, às especificidades da formação, às horas de estudos demandadas pelo curso, à preocupação com os direitos dos sujeitos assistidos e destacam a sensação de invisibilidade experimentada ao se identificar como estudante de terapia ocupacional. Os docentes do curso se apresentam solícitos para a escuta e acolhida das demandas dos estudantes, realizadas informalmente Conclusão: Ao abordar tal tema com estudantes de terapia ocupacional, cuja caracterização mostra -se próxima, comum, ao grupo ampliado de estudantes universitários, o presente estudo colabora com os estudos e ações de saúde mental de acadêmicos de outros cursos e com seus formadores.
Palavras-chave: Estudantes. Saúde Mental. Terapia Ocupacional
REAL-TIME MONITORING FOR DETECTING LAKE POLLUTION AND BIOTIC CONSERVATION
Authors: Dr. Shalini S  , Sree K Mounika , Prajwal M H  , Nitin Reddy N V  , P Govardhan Reddy  
Published: May 2024

This research unveils a comprehensive system designed to tackle plastic pollution in lakes autonomously, eliminating the necessity for human intervention. By harnessing sensor data and camera imagery processed through the YOLO algorithm, the system identifies plastic debris. It then calculates the debris density and compares it against a preset threshold. Once the threshold is exceeded, an automated email alert containing the density data is sent to relevant authorities. Additionally, water quality sensors are integrated to continuously monitor environmental conditions. Regular updates are provided to enable proactive measures in pollution prevention. This endeavor showcases the utilization of advanced technology to address environmental challenges and safeguard aquatic ecosystems' health. By employing automated detection and monitoring mechanisms, the system offers a sustainable approach to combat plastic pollution in lakes, fostering environmental conservation endeavors.
Integrated Bioinformatics Analysis Reveals ceRNA Triplet Related to Apoptosis in Gastric Cancer
Authors: Nath Anju R. , Natarajan Jeyakumar 
Published: May 2024

Apoptosis is a form of programmed cell death and evading the apoptosis is a milestone in gastric cancer (GC) tumorigenesis. Various RNAs such as miRNA (microRNA), mRNA (messenger RNA), lncRNA (long non-coding RNA), circRNA (circular RNA), play crucial roles in the apoptosis mechanism. In this present study, we aimed to understand the role played by these RNAs in apoptosis in GC. We constructed a ceRNA (competitive endogenous RNA) network using the expression profiles obtained from SRA (Sequence Read Archive) and GEO (Gene Expression Omnibus) datasets. After network construction, the differentially expressed mRNAs were used for gene prioritization. The prioritized genes and the RNAs interacting with them were analyzed to study their role in GC apoptosis. Then, we performed functional and pathway analysis to understand the role played by these genes in gastric cancer. This resulted in 37 miRNA-mRNA interactions, one miRNA-lncRNA interaction, and 17 miRNA-circRNA interactions. The binding site analysis resulted in 10 miRNAs that share common MRE (miRNA Response Elements) among mRNA, lncRNAs, circRNA. Besides, we found 33 miRNA-mRNA-circRNA and two miRNA-mRNA-lncRNA valid interactions. Integration of multiple omics datasets revealed dysregulated genes, including IGF1, MME, CCND2, CDH2, and COL1A1, implicated in GC apoptosis. Functional enrichment analysis highlighted pathways related to apoptosis, with CCND2 emerging as a key player. The integrative methodology has revealed a new potential diagnostic biomarker for the regulation of gastric cancer (GC) apoptosis: the CCND2-miR-141-3p-hsa_circ_0008035 ceRNA triplet. This discovery offers fresh perspectives into the intricate regulatory pathways governing gene expression in GC, promising significant insights into its pathology.

Received: 6 January 2024 | Revised: 25 April 2024 | Accepted: 10 May 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
The data that support the findings of this study are openly available in NCBI database at https://www.ncbi.nlm.nih.gov/sra; in Gene Expression Omnibus (GEO) at https://www.ncbi.nlm.nih.gov/geo/; in ENCORI from https://academic.oup.com/nar/article/42/D1/D92/1063720?login=false.

Author Contribution Statement
Anju R. Nath: Conceptualization, Methodology, Data Curation, Writing – original draft, Visualization. Jeyakumar Natarajan: Writing – review & editing, Supervision.
Factors controlling spatiotemporal variability of soil carbon accumulation and stock estimates in a tidal salt marsh
Authors: Fettrow Sean , Wozniak Andrew , Michael Holly A. , Seyfferth Angelia L. 
Published: May 2024

Abstract. Tidal salt marshes are important contributors to soil carbon (C) stocks despite their relatively small land surface area. Although it is well understood that salt marshes have soil C burial rates orders of magnitude greater than those of terrestrial ecosystems, there is a wide range in accrual rates among spatially distributed marshes. In addition, wide ranges in C accrual rates also exist within a single marsh ecosystem. Tidal marshes often contain multiple species of cordgrass due to variations in hydrology and soil biogeochemistry caused by microtopography and distance from tidal creeks, creating distinct subsites. Our overarching objective was to observe how soil C concentration and dissolved organic carbon (DOC) vary across four plant phenophases and across three subsites categorized by unique vegetation and hydrology. We also investigated the dominant biogeochemical controls on the spatiotemporal variability of soil C and DOC concentrations. We hypothesized that subsite biogeochemistry drives spatial heterogeneity in soil C concentration, and this causes variability in total soil C and DOC concentrations at the marsh scale. In addition, we hypothesized that soil C concentration and porewater biogeochemistry vary temporally across the four plant phenophases (i.e., senescence, dormancy, green-up, maturity). To test these interrelated hypotheses, we quantified soil C and DOC concentrations in 12 cm sections of soil cores (0–48 cm depth) across time (i.e., phenophase) and space (i.e., subsite), alongside several other porewater biogeochemical variables. Soil C concentration varied significantly (p < 0.05) among the three subsites and was significantly greater during plant dormancy. Soil S, porewater sulfide, redox potential, and depth predicted 44 % of the variability in soil C concentration. There were also significant spatial differences in the optical characterization properties of DOC across subsites. Our results show that soil C varied spatially across a marsh ecosystem by up to 63 % and across plant phenophase by 26 %, causing variability in soil C accrual rates and stocks depending on where and when samples are taken. This shows that hydrology, biogeochemistry, and plant phenology are major controls on salt marsh C content. It is critical to consider spatiotemporal heterogeneity in soil C concentration and porewater biogeochemistry to account for these sources of uncertainty in C stock estimates. We recommend that multiple locations and sampling time points are sampled when conducting blue C assessments to account for ecosystem-scale variability.
European topsoil bulk density and organic carbon stock database (0–20 cm) using machine-learning-based pedotransfer functions
Authors: Chen Songchao , Chen Zhongxing , Zhang Xianglin , Luo Zhongkui , Schillaci Calogero , Arrouays Dominique , Richer-de-Forges Anne Christine , Shi Zhou 
Published: May 2024

Abstract. Soil bulk density (BD) serves as a fundamental indicator of soil health and quality, exerting a significant influence on critical factors such as plant growth, nutrient availability, and water retention. Due to its limited availability in soil databases, the application of pedotransfer functions (PTFs) has emerged as a potent tool for predicting BD using other easily measurable soil properties, while the impact of these PTFs' performance on soil organic carbon (SOC) stock calculation has been rarely explored. In this study, we proposed an innovative local modeling approach for predicting BD of fine earth (BDfine) across Europe using the recently released BDfine data from the LUCAS Soil (Land Use and Coverage Area Frame Survey Soil) 2018 (0–20 cm) and relevant predictors. Our approach involved a combination of neighbor sample search, forward recursive feature selection (FRFS), and random forest (RF) models (local-RFFRFS). The results showed that local-RFFRFS had a good performance in predicting BDfine (R2 of 0.58, root mean square error (RMSE) of 0.19 g cm−3, relative error (RE) of 16.27 %), surpassing the earlier-published PTFs (R2 of 0.40–0.45, RMSE of 0.22 g cm−3, RE of 19.11 %–21.18 %) and global PTFs using RF models with and without FRFS (R2 of 0.56–0.57, RMSE of 0.19 g cm−3, RE of 16.47 %–16.74 %). Interestingly, we found that the best earlier-published PTF (R2 = 0.84, RMSE = 1.39 kg m−2, RE of 17.57 %) performed close to the local-RFFRFS (R2 = 0.85, RMSE = 1.32 kg m−2, RE of 15.01 %) in SOC stock calculation using BDfine predictions. However, the local-RFFRFS still performed better (ΔR2 > 0.2) for soil samples with low SOC stocks (< 3 kg m−2). Therefore, we suggest that the local-RFFRFS is a promising method for BDfine prediction, while earlier-published PTFs would be more efficient when BDfine is subsequently utilized for calculating SOC stock. Finally, we produced two topsoil BDfine and SOC stock datasets (18 945 and 15 389 soil samples) at 0–20 cm for LUCAS Soil 2018 using the best earlier-published PTF and local-RFFRFS, respectively. This dataset is archived on the Zenodo platform at https://doi.org/10.5281/zenodo.10211884 (S. Chen et al., 2023). The outcomes of this study present a meaningful advancement in enhancing the predictive accuracy of BDfine, and the resultant BDfine and SOC stock datasets for topsoil across the Europe enable more precise soil hydrological and biological modeling.
Sturingsvraagstukken bij publieke inkoop: navigeren tussen controle en vertrouwen
Authors: Grandia Jolien , Kuitert Lizet 
Published: May 2024

Governance matters in public procurement: navigating between control and trust
This introductory article for the special issue on governance matters in public procurement explores the significant impact procurement has on markets and society. It delves into the intricate balance between control and trust within the procurement process, contrasting traditional contractual governance with relational governance. Contributions in this special issue shed light on various governance issues, from crisis management to sustainability transitions and supplier management. A recurring theme across the articles is the call for increased flexibility, professionalisation, and collaboration in procurement, recognising the necessity of balancing control and trust. This article offers insights into the challenges and opportunities inherent in public procurement, emphasising the need for a strategic approach to navigate the complexities of contemporary procurement issues.
De governance van inkoop in crisistijd
Authors: Grandia Jolien , Warsen Rianne 
Published: May 2024

The governance of procurement in times of crises: Balancing between control strategies: contract, relationship or laissez-faire?
In this article, we demonstrate how the governance of procurement processes unfolded during the acquisition of face masks and other personal protective equipment amid the COVID-19 crisis. An extensive document analysis was conducted, spanning January 2020 to December 2021, and encompassing over 522 documents, including news articles, parliamentary records, and internal communications. Our research reveals that, under the pressure of a crisis, the mode of control changes, and there are instances where a conscious decision is made not to actively manage the process. We refer to this as ‘laissez-faire governance.’ However, this approach can lead to challenges later in the procurement process and limited possibilities for control at a later stage, thereby posing accountability challenges, particularly in the public domain. Based on our study, we conclude that there does not necessarily need to be more or better control during crises, but rather a focus on prioritisation: when and for what aspects is control essential? And when can a more hands-off approach be adopted?
Een gepaste aanpak van grand challenges?
Authors: Soltani Pedram , Hermans Marleen , Straub Ad , Bosch-Rekveldt Marian 
Published: May 2024

A suitable approach to grand challenges? Governance of integrated urban transformations implies dealing with complexity and uncertainty
In this article, we draw lessons from the set-up and contractual and relational governance of an integrated urban transformation. We investigated whether and how the approach of this grand challenge in the built environment addresses complexity and uncertainty. Our research demonstrates the importance of an integrated programmatic approach, bringing together various policy issues, actors and resources to achieve common objectives. To promote value creation, the approach should recognise the complexity of the challenge at hand. This requires joint vision development, attention to diverse actors’ interests and values and coordination of interrelated project and non-project activities. Under financial constraints, there may be an increased demand for complexity reduction and control through strict contractual governance and focus on individual projects. However, this does not serve the overarching goal. In addition to contractual governance, relational flexibility is necessary to address uncertain future circumstances and ensure successful collaboration. Public clients should pay more attention to the coherence and interface between project and non-project activities, mutual trust among partners, joint problem-solving and conflict management.
O ENSINO E A UTILIZAÇÃO DE MÍDIAS DIGITAIS NA EDUCAÇÃO
Authors: Franqueira Alberto da Silva , Souza Adailza Cristina Nunes de , Nunes Adelzira Patrícia Ribeiro , Santos Andreza de Oliveira Franco , Silva Cliciano Vieira da , Damasceno Edilson , Campos Viviane Alves , Gomes Wanderson Teixeira 
Published: May 2024

Este estudo vai demostrar o quanto as mídias digitais estão presentes em diversos segmentos e no contexto escolar, os resultados são bem favoráveis para motivar o ensino e aprendizagem. Com isso, foi feito um estudo com o tema: ’Experiências com mídia digitais e linguagem visual junto aos estudantes’’, e como problema: Por que o uso de mídias digitais no contexto educacional favorece o ensino? Com objetivo geral: Analisar as variedades de mídias digitais disponíveis no mercado com fins educacionais. Com os seguintes objetivos específicos: Avaliar como os docentes estão incorporando as mídias digitais para favorecer o ensinar; mostrar como as mídias digitais modifica a cultura tradicional da prática de estudos e evidenciar como a tecnologia digital pode trazer vantagens ao incluir nas práxis pedagógicas. Tendo como justificativa a grande relevância do tema no contexto atual da sociedade, partindo do princípio no qual o estudo em sua amplitude permite deslumbrar o quanto a mídia digital em variados contextos, pode proporcionar uma melhor comunicação em várias áreas de atuação, favorecendo assim o campo educacional. A metodologia da pesquisa foi a bibliográfica, com revisão, leitura, análise com o objetivo de executar os escritos e estruturar de acordo com o estabelecido, esclarecendo os dados pertinentes. Com isso, ficou evidente, o quanto a educação, conscientização se faz necessário para o uso das tecnologias digitais para então ter-se respeito e equilíbrio no uso. A tecnologia digital está em constante desenvolvimento, então a junção ao ensino aprendizado, idealiza uma cultura de comunicação e conhecimento efetivo.
Genetic Landscape and Its Prognostic Impact in Children With Langerhans Cell Histiocytosis
Authors: Wang Chan-Juan , Cui Lei , Li Shuang-Shuang , Ma Hong-Hao , Wang Dong , Lian Hong-Yun , Zhao Yun-Ze , Zhang Li-Ping , Li Wei-Jing , Zhang Qing , Zhao Xiao-Xi , Yang Ying , Huang Xiao-Tong , Liu Wei , Wang Yi-Zhuo , Wu Wan-Shui , Wang Tian-You , Zhang Rui , Li Zhi-Gang 
Published: May 2024

Context.—
Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm that predominantly affects young children.

Objective.—
To investigate genetic alterations and their correlation with clinical characteristics and prognosis in pediatric LCH.

Design.—
We performed targeted sequencing to detect mutations in LCH lesions from pediatric patients.

Results.—
A total of 30 genomic alterations in 5 genes of the MAPK pathway were identified in 187 of 223 patients (83.9%). BRAF V600E (B-Raf proto-oncogene, serine/threonine kinase) was the most common mutation (51.6%), followed by MAP2K1 (mitogen-activated protein kinase kinase 1) alterations (17.0%) and other BRAF mutations (13.0%). ARAF (A-Raf proto-oncogene, serine/threonine kinase) and KRAS (KRAS proto-oncogene, GTPase) mutations were relatively rare (2.2% and 0.9%, respectively). Additionally, FNBP1 (formin-binding protein 1)::BRAF fusion and MAP3K10 (mitogen-activated protein kinase kinase 10) mutations A17T and R823C were identified in 1 case each, with possible constitutive activation of ERK1/2 phosphorylation. BRAF V600E was more frequent in patients with risk organ involvement, while MAP2K1 mutation was more prevalent in patients with single-system LCH (P = .001). BRAF V600E was associated with craniofacial bone, skin, liver, spleen, and ear involvement (all P &lt; .05). Patients with other BRAF mutations had a higher proportion of spinal column involvement (P = .006). Univariate analysis showed a significant difference in progression-free survival among the 4 molecular subgroups for patients treated with first-line therapy (P = .02). According to multivariate analysis, risk organ involvement was the strongest independent adverse prognostic factor (hazard ratio, 8.854; P &lt; .001); BRAF or MAP2K1 mutation was not an independent prognostic factor.

Conclusions.—
Most pediatric patients with LCH carry somatic mutations involving the MAPK pathway, correlating with clinical characteristics and outcomes for first-line chemotherapy.