bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability and Validity of Child/Adolescent Food Frequency Questionnaires That Assess Foods and/or Food Groups
Authors: Kolodziejczyk Julia K. , Merchant Gina , Norman Gregory J. 
Published: March 2012

ABSTRACTObjective:Summarize the validity and reliability of child/adolescent food frequency questionnaires (FFQs) that assess food and/or food groups.Methods:We performed a systematic review of child/adolescent (6–18 years) FFQ studies published between January 2001 and December 2010 using MEDLINE, Cochrane Library, PsycINFO, and Google Scholar. Main inclusion criteria were peer reviewed, written in English, and reported reliability or validity of questionnaires that assessed intake of food/food groups. Studies were excluded that focused on diseased people or used a combined dietary assessment method. Two authors independently selected the articles and extracted questionnaire characteristics such as number of items, portion size information, time span, category intake frequencies, and method of administration. Validity and reliability coefficients were extracted and reported for food categories and averaged across food categories for each study.Results:Twenty‐one studies were selected from 873, 18 included validity data, and 14 included test‐retest reliability data. Publications were from the United States, Europe, Africa, Brazil, and the south Pacific. Validity correlations ranged from 0.01 to 0.80, and reliability correlations ranged from 0.05 to 0.88. The highest average validity correlations were obtained when the questionnaire did not assess portion size, measured a shorter time span (ie, previous day/week), was of medium length (ie, ∼20–60 items), and was not administered to the child's parents.Conclusions:There are design and administration features of child/adolescent FFQs that should be considered to obtain reliable and valid estimates of dietary intake in this population.
Acute Febrile Cholestatic Jaundice in Children
Authors: Taddio Andrea , Pellegrin Maria Chiara , Centenari Chiara , Filippeschi Irene Pellegrini , Ventura Alessandro , Maggiore Giuseppe 
Published: March 2012

ABSTRACTKawasaki disease (KD) is characterized by persistent fever in addition to 4 of 5 signs of mucocutaneous inflammation. Although gastrointestinal involvement does not belong to the classic diagnostic criteria, it has been often associated with KD onset. We reviewed patients who were admitted for febrile cholestatic jaundice between 2003 and 2010 in 2 tertiary pediatric care centers. KD was the second most frequent cause (21%) after viral infections. Considering the relative high frequency of this condition, a high index of suspicion of KD should be maintained in patients presenting with febrile cholestatic jaundice.
Overexpression of PIP2;5 Aquaporin Alleviates Effects of Low Root Temperature on Cell Hydraulic Conductivity and Growth in Arabidopsis
Authors: Lee Seong Hee , Chung Gap Chae , Jang Ji Young , Ahn Sung Ju , Zwiazek Janusz J. 
Published: March 2012

Abstract
The effects of low root temperature on growth and root cell water transport were compared between wild-type Arabidopsis (Arabidopsis thaliana) and plants overexpressing plasma membrane intrinsic protein 1;4 (PIP1;4) and PIP2;5. Descending root temperature from 25°C to 10°C quickly reduced cell hydraulic conductivity (Lp) in wild-type plants but did not affect Lp in plants overexpressing PIP1;4 and PIP2;5. Similarly, when the roots of wild-type plants were exposed to 10°C for 1 d, Lp was lower compared with 25°C. However, there was no effect of low root temperature on Lp in PIP1;4- and PIP2;5-overexpressing plants after 1 d of treatment. When the roots were exposed to 10°C for 5 d, Lp was reduced in wild-type plants and in plants overexpressing PIP1;4, whereas there was still no effect in PIP2;5-overexpressing plants. These results suggest that the gating mechanism in PIP1;4 may be more sensitive to prolonged low temperature compared with PIP2;5. The reduction of Lp at 10°C in roots of wild-type plants was partly restored to the preexposure level by 5 mm Ca(NO3)2 and protein phosphatase inhibitors (75 nm okadaic acid or 1 μm Na3VO4), suggesting that aquaporin phosphorylation/dephosphorylation processes were involved in this response. The temperature sensitivity of cell water transport in roots was reflected by a reduction in shoot and root growth rates in the wild-type and PIP1;4-overexpressing plants exposed to 10°C root temperature for 5 d. However, low root temperature had no effect on growth in plants overexpressing PIP2;5. These results provide strong evidence for a link between growth at low root temperature and aquaporin-mediated root water transport in Arabidopsis.
Back‐scattered electron imaging combined with EBSD technique for characterization of pearlitic steels
Authors: GUO N. , LIU Q. 
Published: March 2012

SummaryMicrostructure of pearlitic steels subjected different heat treatments were characterized combining the usage of back‐scattered electron imaging and electron backscatter diffraction in a scanning electron microscope. The results indicated that the method used in current study enabled the acquisition of pearlite nodule, colony and interlamellar spacing of pearlite structure only through sample preparation of one time. Both the morphology of pearlite lamellae and the crystallographic orientation of ferrite matrix can be released in back‐scattered electron imaging image and electron backscatter diffraction micrograph acquired at the same region. The definitions of pearlite colony and the low‐angle boundaries existed in ferrite matrix were also discussed based on this method.
Impact of neoadjuvant transarterial chemoembolization on tumor recurrence and patient survival after liver transplantation for hepatocellular carcinoma: a retrospective analysis
Authors: Seehofer Daniel , Nebrig Maxim , Denecke Timm , Kroencke Thomas , Weichert Wilko , Stockmann Martin , Somasundaram Rajan , Schott Eckart , Puhl Gero , Neuhaus Peter 
Published: March 2012

AbstractTransarterial chemoembolization (TACE) has gained wide acceptance as a bridge to liver transplantation (LT) in patients with hepatocellular carcinoma (HCC). Aim of this analysis was to compare long‐term results with and without neoadjuvant TACE and to identify subgroups, which particularly benefit from TACE.Patients with HCC transplanted at our center were retrospectively analyzed. The following were excluded to increase consistency: incidental‐HCC, Child‐C, living‐related‐LT, other HCC‐specific‐treatment. Of 336 patients, 177 were subject of this analysis, 71 received TACE and 106 no HCC therapy.Patients with and without TACE showed similar five‐yr survival (73/67%) and recurrence rates (23/29%). Progression on the waiting list was associated with a higher recurrence rate in the TACE (50 vs.12%) and the non‐TACE group (40 vs. 22%). HCC recurrence was reduced in patients inside Milan (0.053) and UCSF (0.037) criteria by neoadjuvant TACE but not outside UCSF (0.99). Also a trend towards an improved survival was seen within these criteria.Our large single center experience suggests that TACE lowers the HCC recurrence rate in patients inside the Milan and UCSF criteria. Moreover, the response to TACE is a good indicator of low recurrence rates. The effect of TACE might be more pronounced in patients with longer waiting time than in this cohort (mean, 4.6 months).
Impact of rifaximin use for hepatic encephalopathy on the risk of early post‐transplant infections in liver transplant recipients
Authors: Sun Hsin‐Yun , Wagener Marilyn , Cacciarelli Thomas V. , Singh Nina 
Published: March 2012

AbstractBackgroundWhether the use of rifaximin for hepatic encephalopathy during liver transplant candidacy has an impact on post‐transplant infections is not known.MethodsWe compared the frequency and spectrum of infections within 90 d post‐transplant in liver transplant recipients who did and did not receive rifaximin for hepatic encephalopathy during transplant candidacy.ResultsOf 110 consecutive liver transplant recipients, 30 (27%) received rifaximin. Rifaximin users were more severely ill based on higher Model for End‐Stage Liver Disease (MELD) score (p = 0.005). When controlled for MELD (stratified by MELD < 30, MELD ≥ 30), the risk of infections was significantly lower in rifaximin vs. no rifaximin recipients (OR = 0.269, 95% CI 0.078–0.0.934, p = 0.026). Rifaximin use was not associated with a higher risk of multidrug resistant bacterial infections (OR = 1.8, 95% CI 0.42–8.35, p = 0.40). The probability of post‐transplant survival at 90 d did not differ for patients with or without rifaximin use (0.90 for both groups, p = 0.56).ConclusionsRifaximin appeared to have a protective effect against early post‐transplant infections in more severely ill liver transplant recipients. Rifaximin use did not select for multidrug resistant bacteria in these patients.
The association between DRESS and the diminished numbers of peripheral B lymphocytes and natural killer cells
Authors: Yazicioglu Mehtap , Elmas Reyhan , Turgut Burhan , Genchallac Tugba 
Published: March 2012

To cite this article: Yazicioglu M, Elmas R, Turgut B, Genchallac T. The association between DRESS and the diminished numbers of peripheral B lymphocytes and natural killer cells. Pediatr Allergy Immunol 2012: 23: 289–296.AbstractDrug reaction with eosinophilia and systemic symptoms (DRESS) is a drug‐induced, severe multiorgan system reaction whose exact pathogenesis remains unknown. This study aimed at evaluating specific changes in peripheral blood lymphocyte subtypes associated with DRESS during antibiotic treatment. We analyzed six patients with DRESS. A complete blood count and peripheral blood lymphocytes immunophenotyping were carried out at symptom onset and at follow‐up visits. Acute‐phase reactants and liver enzymes were measured in all patients. Other tests – viral serology, serum immunoglobulin levels, and skin tests were performed when possible. B‐cell counts were low in all patients at the onset of DRESS, and natural killer (NK) cells were low in all cases except one. During recovery, B‐cell numbers were within a normal range in five patients. In one, there was even a 10‐fold increase in B‐cell counts, although the level was mildly low after 3 months. NK‐cell numbers were within a normal range in three patients. The mean numbers of B cells and NK cells were significantly higher in the second samples compared to the values on admission. Serum IgA and IgM levels were low in one patient. The drug provocation test was positive with cefotaxime in one patient. Viral serology, performed on five patients, was negative. A decrease in B‐cell and NK‐cell counts was the most consistent finding associated with the onset of antibiotic‐induced DRESS in our patients. This immunologic alteration might be a useful predictor of DRESS development.
Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study
Authors: Koutsoubari Ioanna , Papaevangelou Vassiliki , Konstantinou George N. , Makrinioti Heidi , Xepapadaki Paraskevi , Kafetzis Dimitrios , Papadopoulos Nikolaos G. 
Published: March 2012

To cite this article: Koutsoubari I, Papaevangelou V, Konstantinou GN, Makrinioti H, Xepapadaki P, Kafetzis D, Papadopoulos NG. Effect of clarithromycin οn acute asthma exacerbations in children: an open pilot randomized study. Pediatric Allergy Immunology 2012: 23: 385–390.AbstractBackground:  Asthma exacerbations are major contributors to asthma morbidity and rather difficult to treat. There is inconclusive evidence that macrolide antibiotics may have an effect on asthma exacerbations through their antibacterial and/or anti‐inflammatory properties. The aim of the study was to evaluate the efficacy of clarithromycin on medium‐term asthma activity when given as an add‐on therapy in children with acute asthma.Methods:  This pilot, open‐labeled, randomized, prospective study included 40 school‐aged children, with intermittent or mild persistent asthma, presenting with an acute exacerbation. Children were randomized to receive 15 mg/kg of clarithromycin for 3 wk, in addition to their regular (GINA‐guided) exacerbation treatment. The microbial trigger of exacerbations was assessed by serology and PCR. Children were followed up with diary cards for 12 wk; lung function was assessed at entry, 3, and 12 wk after the exacerbation.Results:  Children in the clarithromycin group had significantly more symptom‐free days (78 ± 2 vs. 69 ± 6 days, p < 0.00001) and less total number of periods with loss of control (9 vs. 19, respectively, p = 0.013) during the follow‐up period, compared to controls. Moreover, treated children presented reduced duration of the index episode (5.0 ± 1 vs. 7.5 ± 1 days, p < 0.00001). Lung function did not differ between groups.Conclusions:  When added to regular treatment, a 3‐wk course of clarithromycin was associated with an increase in the number of symptom‐free days, reductions in the number and severity of days with loss of control following index episode, and a decrease in the duration of the initial asthma exacerbation.
Clinical features and outcome of X‐linked lymphoproliferative syndrome type 1 (SAP deficiency) in Japan identified by the combination of flow cytometric assay and genetic analysis
Authors: Kanegane Hirokazu , Yang Xi , Zhao Meina , Yamato Kazumi , Inoue Masami , Hamamoto Kazuko , Kobayashi Chie , Hosono Ako , Ito Yoshikiyo , Nakazawa Yozo , Terui Kiminori , Kogawa Kazuhiro , Ishii Eiichi , Sumazaki Ryo , Miyawaki Toshio 
Published: March 2012

To cite this article: Kanegane H, Yang Xi, Zhao M, Yamato K, Inoue M, Hamamoto K, Kobayashi C, Hosono A, Ito Y, Nakazawa Y, Terui K, Kogawa K, Ishii E, Sumazaki R, Miyawaki T. Clinical features and outcome of X‐linked lymphoproliferative syndrome type 1 (SAP deficiency) in Japan identified by the combination of flow cytometric assay and genetic analysis. Pediatric Allergy Immunology 2012: 23: 488–493.AbstractObjective:  X‐linked lymphoproliferative syndrome (XLP) type 1 is a rare immunodeficiency, which is caused by mutations in SH2D1A gene. The prognosis of XLP is very poor, and hematopoietic stem cell transplantation (HSCT) is the only curative therapy. We characterized the clinical features and outcome of Japanese patients with XLP‐1.Methods:  We used a combination of flow cytometric analysis and genetic analysis to identify XLP‐1 and reviewed the patient characteristics and survival with HSCT.Results:  We identified 33 patients from 21 families with XLP‐1 in Japan. Twenty‐one of the patients (65%) who did not undergo a transplant died of the disease and complications. Twelve patients underwent HSCT, and 11 of these (92%) survived.Conclusion:  We described the clinical characteristics and outcomes of Japanese patients with XLP‐1, and HSCT was the only curative therapy for XLP‐1. The rapid and accurate diagnosis of XLP with the combination of flow cytometric assay and genetic analysis is important.
Allergy in children: practical recommendations of the Finnish Allergy Programme 2008–2018 for prevention, diagnosis, and treatment
Authors: Pelkonen Anna S. , Kuitunen Mikael , Dunder Teija , Reijonen Tiina , Valovirta Erkka , Mäkelä Mika J. 
Published: March 2012

To cite this article: Pelkonen AS, Kuitunen M, Dunder T, Reijonen T, Valovirta E, Mäkelä MJ. Allergy in children: practical recommendations of the Finnish Allergy Programme 2008–2018 for prevention, diagnosis, and treatment. Pediatr Allergy Immunol 2012: 23: 103–116.AbstractThe Finnish Allergy Programme 2008–2018 is a comprehensive plan intended to reduce the burden of allergies. One basic goal is to increase immunologic tolerance and change attitudes to encourage health instead of medicalizing common and mild allergy symptoms. The main goals can be listed as to: (i) prevent the development of allergic symptoms; (ii) increase tolerance to allergens; (iii) improve diagnostics; (iv) reduce work‐related allergies; (v) allocate resources to manage and prevent exacerbations of severe allergies, and (vi) reduce costs caused by allergic diseases. So far, the Allergy Programme has organized 135 educational meetings for healthcare professionals around Finland. These meetings are multidisciplinary meetings gathering together all healthcare professionals working with allergic diseases. Since the start of the program in spring 2008, more than 7000 participants have taken part. Educational material for patient care has been provided on special Web sites/therapeutic portals, which can be accessed by all physicians caring for allergic patients. Local Allergy Working Groups have been created in different parts of Finland. As a part of the Programme, a set of guidelines for child welfare clinics was prepared. Child welfare clinics have a key role in the screening of illnesses and providing advice to families with a symptomatic child. The guidelines aimed to facilitate pattern recognition and clinical decision making for public health nurses and doctors are described in this paper.
A field test for host fruit odour discrimination and avoidance behaviour for Rhagoletis pomonella flies in the western United States
Authors: SIM S. B. , MATTSSON M. , FEDER JASMINE L. , CHA D. H. , YEE W. L. , GOUGHNOUR R. B. , LINN JR C. E. , FEDER JEFFREY L. 
Published: March 2012

AbstractPrezygotic isolation due to habitat choice is important to many models of speciation‐with‐gene‐flow. Habitat choice is usually thought to occur through positive preferences of organisms for particular environments. However, avoidance of non‐natal environments may also play a role in choice and have repercussions for post‐zygotic isolation that preference does not. The recent host shift of Rhagoletis pomonella (Diptera: Tephritidae) from downy hawthorn, Crataegus mollis, to introduced apple, Malus domestica, in the eastern United States is a model for speciation‐with‐gene‐flow. However, the fly is also present in the western United States where it was likely introduced via infested apples ≤ 60 years ago. R. pomonella now attacks two additional hawthorns in the west, the native C. douglasii (black hawthorn) and the introduced C. monogyna (English ornamental hawthorn). Flight tunnel tests have shown that western apple‐, C. douglasii‐ and C. monogyna‐origin flies all positively orient to fruit volatile blends of their respective natal hosts in flight tunnel assays. Here, we show that these laboratory differences translate to nature through field‐trapping studies of flies in the state of Washington. Moreover, western R. pomonella display both positive orientation to their respective natal fruit volatiles and avoidance behaviour (negative orientation) to non‐natal volatiles. Our results are consistent with the existence of behaviourally differentiated host races of R. pomonella in the west. In addition, the rapid evolution of avoidance behaviour appears to be a general phenomenon for R. pomonella during host shifts, as the eastern apple and downy hawthorn host races also are antagonized by non‐natal fruit volatiles.
Assessment of quality of life in pregnant Japanese women: Comparison of hospitalized, outpatient, and non‐pregnant women
Authors: Nakamura Yasuka , Takeishi Yoko , Atogami Fumi , Yoshizawa Toyoko 
Published: March 2012

AbstractThis cross‐sectional study explored the comfort and quality of life in hospitalized, preterm, pregnant women compared with pregnant outpatients, and identified the relationship between comfort, quality of life, and hospitalization. Two‐hundred‐and‐twenty‐one hospitalized pregnant women who met the inclusion criteria were recruited from obstetric units, and 1015 outpatient pregnant women were recruited from obstetric outpatient units in Japan. The women were questioned on six domains of the Japanese Short‐Form‐36 version 2 (bodily pain, general health, vitality, role emotional, social functioning, and mental health) and on their subjective comfort. A total of 189 hospitalized pregnant women and 503 low‐risk pregnant women were analyzed. Subjective comfort and all six domains of health‐related quality of life showed significantly lower scores for hospitalized women than outpatient women (P < 0.05–0.001). The mean differences in social functioning and role–emotional domains between the two groups were particularly marked. The result of this study suggests that these patients require positive psychological support to improve their comfort and quality of life.
Risk factors related to hazardous alcohol consumption among Korean men with hypertension
Authors: Kim Oksoo , Kim Bo Hye , Jeon Hae Ok 
Published: March 2012

AbstractThe present study examines the alcohol consumption behaviors and risk factors related to hazardous alcohol consumption in men with hypertension in South Korea. The participants were 490 Korean hypertensive men > 20 years of age. The Alcohol Use Disorders Identification Test was used to detect hazardous alcohol consumption. The majority of the participants were current drinkers, and 37.4% were hazardous drinkers. However, very few participants had received consultation about alcohol consumption. Of the participants, 37.7% were current smokers, and almost half of them smoked more than one pack of cigarettes daily. The hazardous drinkers smoked much more than the normal drinkers, and their stress levels were higher than that of normal drinkers. Participants aged 40–49 and 50–59 years (odds ratio = 7.91, 95% confidence interval = 1.50–41.70; odds ratio = 7.57, 95% confidence interval = 1.31–43.70), those without stroke (odds ratio = 4.86, 95% confidence interval = 1.33–17.77), and current smokers (odds ratio = 4.24, 95% confidence interval = 2.00–8.98) were more likely to be involved in hazardous alcohol consumption. Successful blood pressure management will necessitate the education of such hypertensive men with consideration of their risk factors.
Dietary pattern and mortality in Japanese elderly patients with type 2 diabetes mellitus: Does a vegetable‐ and fish‐rich diet improve mortality? An explanatory study
Authors: Iimuro Satoshi , Yoshimura Yukio , Umegaki Hiroyuki , Sakurai Takashi , Araki Atsushi , Ohashi Yasuo , Iijima Katsuya , Ito Hideki ,   the Japanese Elderly Diabetes Intervention Trial Study Group
Published: March 2012

Aim:  To assess the effect of dietary patterns on all deaths and diabetes‐related deaths in the Japanese Elderly Diabetes Intervention Trial (J‐EDIT).Methods:  We investigated relationships between that of overall mortality and dietary pattern, and diabetes‐related deaths and dietary pattern as observed among 912 registered cases of the J‐EDIT study, which is a prospective follow‐up study of elderly Japanese type 2 diabetic patients.Results:  Factor analysis with the factor number 3 led to deriving three dietary patterns (healthy type, snack type and greasy type). The relationship between these patterns and overall mortality or diabetes‐related death was investigated. Although not statistically significant, there was a lower tendency of overall mortality and diabetes‐related deaths for the healthy type dietary pattern. When the tendencies of overall mortality were analyzed for “young‐old,” who are younger than 75 years‐of age, and “old‐old” of over 75 years‐of‐age, the mortality rate for the greasy type and healthy type dietary patterns were nearly the same and higher than the snack type dietary pattern in young‐old. In contrast, in old‐old, a higher mortality rate was reported for the greasy type dietary pattern and a lower mortality rate was reported for the healthy type dietary pattern. The hazard ratio by Cox regression analysis for greasy type to healthy type in old‐old was 3.03 (P = 0.04, CI 1.07–8.57). Furthermore, in old‐old, as vegetable consumption increased, the lower the tendency foroverall mortality, and the more fish that was consumed, the overall mortality significantly decreased (P = 0.020) in the tertile.Conclusions:  The greasy type dietary pattern with an increased amount of sugar, fat and meat led to poor life prognosis for elderly Japanese type 2 diabetic patients. The healthy type dietary pattern rich in vegetable and fish, which is similar to the Mediterranean diet and Dietary Approach to Stop Hypertension diet, was suggested to improve life prognosis. Geriatr Gerontol Int 2012; 12 (Suppl. 1): 59–67.