bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Accelerated Heck Reaction Using ortho‐Palladated Complex with Controlled Microwave Heating.
Authors: Hajipour Abdol R. , Karami Kazem , Pirisedigh Azadeh 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Synthesis of Thioesters in Water.
Authors: Boeini Hassan Zali , Kashan Maryam Eshghi 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (S)‐Ketamine via [1,3]‐Chirality Transfer of a Stereocenter Created by Enantioselective Aldol Reaction.
Authors: Yokoyama Takeshi , Yokoyama Reiko , Nomura Satoshi , Matsumoto Satoshi , Fujiyama Ryoji , Kiyooka Syun‐ichi 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of 4‐Substituted 4,5‐Dihydroisoxazol‐3‐ols from Morita—Baylis—Hillman Bromides.
Authors: Zhong Weihui , Liu Yongliang , Guo Baoming 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Some Novel Thiazolidine‐2,4‐dione Derivatives.
Authors: Mentese Arzu , Ceylan‐Uenluesoy Meltem , Bozdag‐Duendar Oya , Altanlar Nurten , Ertan Rahmiye 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermolysis of N‐Arylenamino‐N‐arylimine Hydrochloride Derivatives: A Short and Improved Synthesis of 2‐Methylthieno[2,3‐c]acridine Derivatives.
Authors: Maiti Tuhin B. , Kar Gandhi K. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convergent Stereoselective Synthesis of Quinolizidines and Indolizidines: Chemoselective Coupling of 2‐Hydroxymethyl‐Substituted Allylic Silanes with Imines.
Authors: Yang Dexi , Micalizio Glenn C. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Isoquinuclidinones by Direct Imino‐Diels—Alder Type Reaction Catalyzed by L‐Proline.
Authors: Quinones Noelia , Aznar Fernando , Cabal Maria‐Paz 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Production of Sulfur Heterocycles (Dihydrobenzodithiins): A New Application of Ligand‐Based Alkene Reactivity.
Authors: Harrison Daniel J. , Fekl Ulrich 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies on Synthesis of 2‐Methyl‐3,1‐benzoxazine‐4(4H)‐one Dyes and Their Application on Nylon and Polyester Fibres.
Authors: Navadiya H. D. , Undavia N. K. , Patwa B. S. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactions of Selenium Dichloride and Dibromide with Divinyl Selenide: Synthesis of Novel Selenium Heterocycles and Rearrangement of 2,6‐Dihalo‐1,4‐diselenanes.
Authors: Potapov Vladimir A. , Amosova Svetlana V. , Volkova Kaleria A. , Penzik Maxim V. , Albanov Alexander I. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Gold‐Catalyzed Cycloaddition of Functionalized Ketoenynes: Synthesis of (+)‐Orientalol F.
Authors: Jimenez‐Nunez Eloisa , Molawi Kian , Echavarren Antonio M. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Constituents and Their Bioactivities of Houttuynia cordata.
Authors: Chou Shu‐Chen , Su Chung‐Ren , Ku Yuh‐Chi , Wu Tian‐Shung 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkali Metal 1:1:x Borates
Authors: Zviedre I. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: TRANSDIP — An Authentic trans‐Chelating Ligand: Use of a Molecular Cavity to Form a New Class of Diphosphines
Authors: Poorters Laurent , Lejeune Manuel , Armspach Dominique , Matt Dominique 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbohydrate Hydrazones and Osazones as Organic Raw Materials for Nucleosides and Heterocycles — Revised and Updated
Authors: El Ashry El Sayed H. 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sensors for the Optical Detection of Cyanide Ion
Authors: Xu Zhaochao , Chen Xiaoqiang , Kim Ha Na , Yoon Juyoung 
Published: March 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Bifunctional Eu3+‐doped Gd2O3 nanoparticles as a luminescent and T1 contrast agent for stem cell labeling
Authors: Shi Zhilong , Neoh K. G. , Kang E. T. , Shuter Borys , Wang Shih‐Chang 
Published: March 2010

AbstractMagnetic resonance tracking of stem cells has recently become an emerging application for investigating cell–tissue interactions and guiding the development of effective stem cell therapies for regeneration of damaged tissues and organs. In this work, anionic Eu3+‐doped Gd2O3 hybrid nanoparticles were applied as a contrast agent both for fluorescence microscopy and T1‐weighted MRI. The nanoparticles were synthesized through the polyol method and further modified with citric acid to obtain anionic nanoparticles. These nanoparticles were internalized into human mesenchymal stem cells (hMSCs) as confirmed by confocal laser scanning microscopy and quantified by inductively coupled plasma–mass spectrometry. MTT assay of the labeled cells showed that the nanoparticles did not possess significant cytotoxicity. In addition, the osteogenic, adipogenic and chondrogenic differentiation of the hMSCs was not influenced by the labeling process. With MRI, the in vitro detection threshold of cells after incubation with nanoparticles at a Gd concentration of 0.5 mMfor 2 h was estimated to be about 10 000 cells. The results from this study indicate that the biocompatible anionic Gd2O3 nanoparticles doped with Eu3+ show promise both as a luminescent and T1 contrast agent for use in visualizing hMSCs. Copyright © 2010 John Wiley & Sons, Ltd.
Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer
Authors: Nakayama Naomi , Nakayama Kentaro , Shamima Yeasmin , Ishikawa Masako , Katagiri Atsuko , Iida Kouji , Miyazaki Khoji 
Published: March 2010

AbstractBACKGROUND:This study examined the clinical significance of CCNE1 (Cyclin E1) amplification and assessed whether CCNE1 is a potential therapeutic target in ovarian cancer.METHODS:CCNE1 expression and amplification in ovarian cancer was assessed by immunohistochemistry, fluorescence in situ hybridization and clinical data collected by retrospective chart review. CCNE1 gene knockdown using silencing RNA and a CCNE1 gene transfection system were used to asses CCNE1 function in tissue samples of ovarian cancer.RESULTS:Gene amplification was identified in 18 (20.4%) of 88 ovarian carcinomas. CCNE1 copy number significantly correlated with CCNE1 protein expression (r = 0.522, P < .0001). CCNE1 amplification significantly correlated with shorter disease‐free survival and overall survival (P < .001). There were nonsignificant trends between high protein expression and poor disease‐free survival (P = .2865) and overall survival (P = .1248). Multivariate analysis showed gene amplification was an independent prognostic factor for disease‐free survival and overall survival after standard platinum‐taxane chemotherapy (P = .0274, P = .0023). Profound growth inhibition and apoptosis were observed in silencing RNA‐treated cancer cells with gene amplification compared with results in cancer cells with CCNE1 moderate expression without gene amplification or with low CCNE1 expression. CCNE1 overexpression stimulated proliferation in ovarian cancer cell lines ES2 and TOV‐21G, which have lower endogenous CCNE1 expression.CONCLUSIONS:These findings indicate that CCNE1 overexpression is critical to growth and survival of ovarian cancer tumors with CCNE1 gene amplification. Furthermore, they suggest that CCNE1 silencing RNA‐induced phenotypes depend on amplification status of ovarian cancers. Therefore, CCNE1‐targeted therapy may benefit ovarian cancer patients with CCNE1 amplification. Cancer 2010. © 2010 American Cancer Society.
The incidence of venous thromboembolism and its effect on survival among patients with primary bladder cancer
Authors: Sandhu Rasanamar , Pan Chong‐Xian , Wun Ted , Harvey Danielle , Zhou Hong , White Richard H. , Chew Helen K. 
Published: March 2010

AbstractBACKGROUND:The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population‐based study of patients with bladder cancer have not been identified previously.METHODS:The California Cancer Registry was merged with the California Patient Discharge Data Set to determine the incidence of VTE in patients with newly diagnosed bladder cancer within a 6‐year period. Cox proportional hazards models were used to determine the risk factors for VTE and the effects of VTE on survival.RESULTS:Among 24,861 patients with bladder cancer, the 2‐year incidence of VTE was 1.9%. The highest incidence of VTE occurred in the first 6 months regardless of age, sex, race, tumor stage, or histologic subtype. In a multivariate model, significant risk factors for the development of VTE included major surgery, advancing disease stage, and increasing number of comorbidities. Compared with the general population, the 1‐year standardized incidence ratio for VTE in the bladder cancer cohort was 5.3 (95% confidence interval, 4.8‐5.9). Among patients with bladder cancer, significant risk factors for death included advancing disease stage, increasing comorbidities, African‐American race, nontransitional cell carcinoma histology, and the development of VTE.CONCLUSIONS:Patients with bladder cancer had a 1.9% 2‐year incidence of VTE. Metastatic disease was the strongest predictor of both VTE and death. It was noteworthy that cancer‐associated surgery was associated with a higher risk of VTE, which differed from the results reported from other studies in solid tumors. VTE was a significant predictor of death in the first 2 years. Cancer 2010. © 2010 American Cancer Society.
KRAS mutation status in primary nonsmall cell lung cancer and matched metastases
Authors: Cortot Alexis B. , Italiano Antoine , Burel‐Vandenbos Fanny , Martel‐Planche Ghyslaine , Hainaut Pierre 
Published: March 2010

AbstractBACKGROUND:The objective of this study was to determine whether the mutation status of the v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) and epidermal growth factor receptor (EGFR) differed between primary tumors and matched distant metastases in nonsmall cell lung cancer (NSCLC).METHODS:Patients who underwent resection for both primary NSCLC and matched distant metastases were included in the study. KRAS and EGFR mutation status were assessed by polymerase chain reaction (PCR) amplification and direct sequencing on both primary tumors and metastases. For KRAS analysis, mutant‐enriched PCR (ME‐PCR) was performed in case of discordance between a primary tumor and its matched metastasis.RESULTS:Twenty‐one patients were included. No EGFR mutations were detected. KRAS mutations were detected in 6 patients (28%). In all patients, the mutations identified by direct sequencing were discordant between the primary tumor and the matched metastasis. The use of ME‐PCR allowed a resolution of the discordance in 3 of the 6 cases by demonstrating the presence of low levels of mutant KRAS in lesions that were negative by direct sequencing.CONCLUSIONS:Highly sensitive tools are required to identify biomarkers. The KRAS mutation status mostly was concordant between primary tumors and matched distant metastases. In a few patients, KRAS mutation status differed between different tumor sites. Cancer 2010. © 2010 American Cancer Society.
Serum sE‐selectin levels and carcinoembryonic antigen mRNA‐expressing cells in peripheral blood as prognostic factors in colorectal cancer patients
Authors: Ferroni Patrizia , Roselli Mario , Spila Antonella , D'Alessandro Roberta , Portarena Ilaria , Mariotti Sabrina , Palmirotta Raffaele , Buonomo Oreste , Petrella Giuseppe , Guadagni Fiorella 
Published: March 2010

AbstractBACKGROUND:This study analyzed the possible prognostic value of presurgical serum soluble (s)E‐selectin levels and/or carcinoembryonic antigen (CEA) mRNA positivity in predicting the disease‐free survival of colorectal cancer (CRC) patients.METHODS:CEA mRNA (obtained from blood‐borne cells by reverse transcriptase‐polymerase chain reaction [RT‐PCR]), tumor necrosis factor‐α (TNF‐α), and sE‐selectin levels were analyzed in blood samples obtained from 78 patients with primary (n = 62) or recurrent (n = 16) CRC, 40 patients with benign colorectal (CR) diseases, and 78 controls.RESULTS:CEA mRNA positivity by RT‐PCR was significantly associated with advanced stage (P < .05). Median baseline sE‐selectin levels were higher in patients with CRC (43 ng/mL) compared with controls (36 ng/mL) or patients with benign CR diseases (31 ng/mL, P < .001). These were significantly associated with CEA mRNA positivity by RT‐PCR (P < .05). Multivariate analysis by forward stepping showed that elevated TNF‐α (P = .001) and CEA mRNA positivity by RT‐PCR (P = .0001) were independent predictors of elevated baseline sE‐selectin levels. Positive presurgical sE‐selectin levels were associated with an increased recurrence rate compared with patients with low levels of this molecule (P < .001). Positivity for both CEA mRNA and sE‐selectin had a negative prognostic impact, with a 5‐year recurrence‐free survival rate of 51% compared with 95% of patients with negative parameters (P < .05).CONCLUSIONS:Detection of presurgical serum sE‐selectin levels and CEA mRNA‐positive blood‐borne cells in CRC patients might provide useful prognostic information in terms of recurrence‐free survival, either alone or in combination, and may help in the choice of more aggressive treatment and/or more strict follow‐up procedures in high‐risk patients. Cancer 2010. © 2010 American Cancer Society.
ENDOR Study of Charge Migration in Photosynthetic Arrays of Rhodobacter sphaeroides
Authors: Hasjim Petersen L. , Lendzian Friedhelm , Ponomarenko Nina , Weber Stefan , Norris James R. 
Published: March 2010

AbstractThe chemistry of bacterial photosynthesis begins in the photosynthetic reaction centre (RC), a protein complex containing a series of electron donor and acceptor molecules. Although the pigments of the RC can absorb light to operate the photochemistry, the bulk of the light is captured in special pigmented proteins, the light harvesting complexes (LHCs), that then transfer the energy to the RC. Ordinarily, the LHCs do not participate in chemical reactions during photosynthesis such that LHCs do not become oxidised upon light irradiation. However, upon chemical oxidation in the dark, cation radicals of bacteriochlorophyll (BChl) can be formed in the light harvesting complex 1 (LH1) of Rhodobacter sphaeroides. As observed by continuous‐wave electron‐paramagnetic resonance (EPR), the charges of the BChl+ cations migrate rather freely about the LH1 complex as in a molecular wire. Remarkably, these LH1 molecular wires continue to function in the frozen, solid state. To investigate the nature of electron–hole transfer and to corroborate the process as revealed by EPR, electron–nuclear double resonance (ENDOR) was recorded at 80 K. ENDOR observed only monomeric bacteriochlorophyll cations. Their signal intensity decreased with increased oxidation while the EPR signal narrowed and increased in size. At the increased oxidation state, the possibility of spin‐spin exchange between two BChl+s within LH1 versus electron–hole transfer is addressed. An energy landscape of the BChl+s in the LH1 is proposed to explain the EPR and ENDOR results.
Mineralization of oriented nano hydroxyapatite in photopolymerized polyacrylamide gel matrix
Authors: Ahymah Joshy M. I. , Elayaraja K. , Suganthi R. V. , Narayana Kalkura S. 
Published: March 2010

AbstractPolyacrylamide hydrogel is a biomaterial and nondegradable water based polymer which is used as tissue filler. Mineralization of hydroxyapatite (HAp) in a UV polymerized acrylamide gel matrix was investigated by varying the concentration of precursors and pH in the range 8, 9 and 10. During polymerization, diammonium hydrogen phosphate ions were impregnated in the gel matrix and subsequently, immersed in the calcium nitrate solution. Thin laminated macroporous structures, embedded with nanospheres and ribbons of HAp were mineralized. The HAp was found to be oriented along c‐axis, which could lead to the preferential binding of the acidic proteins on it's surface. In addition, there was an enlargement of pore sizes with an increase in pH. The laminated structures showed resorbable nature whereas, flake like structures obtained at higher concentrations were found to be bioactive. This composite could be an alternative to the use of silicone gel, to avoid long term risk of fibrosis and migration when implanted. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Temperature dependence of lattice parameters of langasite single crystals
Authors: Kräußlich J. , Höfer S. , Zastrau U. , Jeutter N. , Baehtz C. 
Published: March 2010

AbstractTo determine the coefficient of thermal expansion of trigonal langasite (La3Ga5SiO14) the two independent lattice parametersaandcare measured over a temperature range of 800 °C using X‐ray diffraction on single crystal samples. From the given nonlinear temperature dependence the linear and quadratic thermal coefficients of expansion α11, β11and α33, β33for the two lattice parametersaandccould be deduced. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
No effect of social group composition or size on hippocampal formation morphology and neurogenesis in mountain chickadees (Poecile gambeli)
Authors: Fox Rebecca A. , Roth Timothy C. , LaDage Lara D. , Pravosudov Vladimir V. 
Published: March 2010

AbstractBrain plasticity and adult neurogenesis may play a role in many ecologically important processes including mate recognition, song learning and production, and spatial memory processing. In a number of species, both physical and social environments appear to influence attributes (e.g., volume, neuron number, and neurogenesis) of particular brain regions. The hippocampus in particular is well known to be especially sensitive to such changes. Although social grouping in many taxa includes the formation of male and female pairs, most studies of the relationship between social environment and the hippocampus have typically considered only solitary animals and those living in same‐sex groups. Thus, the aim of this study was to compare the volume of the hippocampal formation, the total number of hippocampal neurons, and the number of immature neurons in the hippocampus (as determined by doublecortin expression) in mountain chickadees (Poecile gambeli) housed in groups of males and females, male–female pairs, same sex pairs of either males or females, and as solitary individuals. The different groups were visually and physically, but not acoustically, isolated from each other. We found no significant differences between any of our groups in hippocampal volume, the total number of hippocampal neurons, or the number of immature neurons. Our results thus provided no support to the hypothesis that social group composition and/or size have an effect on hippocampal morphology and neurogenesis. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 70:538–547, 2010