bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMASI PENGOLAHAN AYAM GORENG BUMBU KUNING DENGAN METODE SOUS VIDE
Authors: Shafira Nindita  , R. Muhammad Zatmodisuwa  , Zayyini Nadhlah  
Published: May 2024

Ayam Goreng Bumbu Kuning merupakan salah satu makanan khas Jawa Timur yang sangat populer ditemui di sudut kota manapun di Indonesia. Makanan ini biasa diolah dengan cara mengungkep ayam dengan bumbu kuning. Bumbu kuning merupakan bumbu yang berupa hasil penghalusan bawang merah, bawang putih, dan kunyit. Pada proses pembuatan, ayam yang sudah diungkep kemudian di deep fried sebelum disajikan untuk mencari warna kecoklatan. Ungkep membuat bumbu dasar menjadi meresap ke dalam bahan makanan dengan hasil bahan makanan menjadi kering dan volume makanan mengalami penyusutan yang sangat banyak. Untuk mengatasi hal ini dilakukan penggantian metode ungkep dengan metode sous vide. Tujuan dari penelitian ini adalah untuk mengetahui kombinasi ayam goreng bumbu kuning dan metode sous vide agar bisa diketahui tehnik pembuatan, tingkat kesukaan, sifat sensoris, kandungan gizi, masa simpan, dan harga pengolahan pokok. Tehnik sous vide yang digunakan dalam pembuatan ayam goreng bumbu kuning adalah 60oC;60 menit, 60oC;75 menit, dan 65oC:60 menit, yang diikuti dengan proses deep frying pada suhu 190oc selama 1 menit. Hasil penelitian menunjukan bahwa ayam goreng bumbu kuning metode sous vide 60oC;60 menit menghasilkan produk yang tingkat kesukaannya lebih tinggi dari ayam goreng bumbu kuning metode ungkep dan paling disukai. Sifat sensoris menunjukan bahwa ayam goreng bumbu kuning metode sous vide 60oC;60 menit menghasilkan tenderness, juiciness, aroma dan rasa tertinggi. Sedangkan ayam goreng bumbu kuning metode sous vide 65oC;60 menit menghasilkan warna tertinggi. Penyimpanan ayam goreng bumbu kuning metode sous vide 60oC;60 menit pada suhu 4oC dapat bertahan selama 30 hari tanpa kehilangan kualitas sensori sebelum mengalami proses spoiled. Sedangkan pada suhu (-18oc) ayam goreng bumbu kuning bisa bertahan selama 60 hari tanpa kehilangan kualitas sensori.
Pengembangan Homestay Berbasis Ramah Disabilitas Tunadaksa di Pulau Pari, Kepulauan Seribu, Jakarta
Authors: Talitha Ananda Nadine  , Telly Chammellia Salsabilla , Darmawan Rahmat 
Published: May 2024

Pariwisata menjadi kebutuhan setiap orang, pelayanan wisata menjadi hak semua orang termasuk bagi penyandang disabilitas terutama pada seseorang dengan disabilitas tuna daksa, tetapi pada faktanya industri pariwisata masih mengabaikan konsep ramah disabilitas terutama pada segi penyediaan fasilitas. Konsep Tourism for All merupakan konsep yang dibuat pada tahun 1989 di Inggris dengan menargetkan industri pariwisata terutama kepada para operator untuk meningkatkan kualitas suatu produk wisata dengan menawarkan produk wisata sesuai dengan ekspetasi berupa kenyamanan, atraksi dan keamanan terutama pada orang-orang yang berkebutuhan khusus. Kajian Pengembangan Homestay Berbasis Ramah Disabilitas Tuna Daksa di Pulau Pari bertujuan untuk memperluas segmentasi wisatawan yang berkunjung ke Pulau Pari dengan melihat potensi pengembangan homestay yang dapat diterapkan dengan menggunakan Konsep Rumah Ramah Disabilitas Tuna Daksa. Dalam penelitian metode yang digunakan adalah kualitatif yaitu memaparkan objek sebagaimana adanya sesuai dengan kondisi saat peneliti melakukan penelitian. Dari hasil penelitian diketahui bahwa homestay yang ada di Pulau Pari masih dikatakan kurang ramah untuk penyandang disabilitas terutama disabilitas tuna daksa dikarenakan masih terdapat kekurangan dalam penyediaan fasilitas khusus bagi pengguna kursi roda seperti tidak ada akses ramp, hand rail, dan lainnya. Berdasarkan kekurangan diatas maka diperlukan adanya standarisasi dan penyesuaian fasilitas homestay yang ramah bagi penyandang disabilitas khususnya tuna daksa.

Kata kunci: Pulau Pari, Homestay, Disabilitas, Tuna Daksa.
Englishpreneurship Program sebagai Upaya Pembelajaran Integeratif di Tingkat Sekolah Dasar
Authors: Tri Kristianti  , Ar Ruhimat Imroati Istibsyaroh , Firdaus Rizalnur 
Published: May 2024

Continuous and impactful education is considered essential for the creation of the 2045 Golden Generation focused on quality education as one of the main pillars alongside economic equality and development. Educators with integrity and adequate competence in their respective fields and expertise are expected to produce a generation with outstanding potential, and capable of enhancing Indonesia's reputation on the international stage. The mismatch between competencies and the demands of Human Resources (HR) needs can significantly affect the quality of teaching. This Community Service Program is focused on achieving maximum results for students by enhancing the quality of educators to meet the Learning Achievement standards in the Independent Curriculum for English, Entrepreneurship, and Project Creative subjects through a training program titled "Young Learners Entrepreneurship" for elementary school teachers. A qualitative descriptive method is applied using interview techniques, classroom observations, and documentation to obtain primary data so that the program can have the greatest impact and benefit for the selected school partner. Hopefully, this community service's results can improve teachers' competencies and boost their confidence when teaching subjects beyond their expertise. This, in turn, allows the involvement of educational technology applications to continue in future service activities.

Abstrak
Pendidikan yang berkesinambungan dan berdampak mutlak diperlukan dalam rangka menuju terciptanya Generasi Emas 2045 yang menitikberatkan pada kualitas Pendidikan yang berkualitas ssebagai salah satu pilar utama disamping pemerataan ekonomi dan pembangunanKewirausahaan serta Project kreatif melalui suatu program pelatihan bertajuk Young Learners Entrepreneurship bagi guru Sekolah Dasar. Metode deskriptif kualitatif diaplikasikan dengan menggunakan teknik wawancara, observasi kelas, dan dokumentasi guna mendapatkan data primer agar program tersebut dapat memberikan dampak dan manfaat yang sebesar-besarnya bagi mitra terpilih. Diharapkan hasil dari pengabdian ini dapat bermanfaat untuk meningkatkan kompetensi guru serta meningkatkan rasa percaya diri ketika mengajarkan mata pelajaran diluar bidang kompetensi sehingga keterlibatan teknologi berupa aplikasi endidikan dapat dilanjutkan pada kegiatan pengabdian di masa mendatang.
Murine orthotopic pancreatic tumor model generation.
Authors: Kim Duk Ki , Jeong Juhee , Jung Kee hoon 
Published: May 2024

Abstract

Approximately 50% of pancreatic cancer patients are diagnosed as stage IV with poor prognosis and show treatment resistance to conventional cytotoxic chemotherapy and recently developed immunotherapy. Therefore, there is an urgent need in developing novel treatment options for pancreatic cancer patients and examine them by using proper preclinical models. Murine orthotopic tumor model is generated by seeding murine cancer cell lines or patient-derived cancer cells into the relevant organ of tumor origin. Significance of the orthotopic pancreatic cancer model have been highlited since it can be easily generated compared to GEMM(Genetically engineered mouse models) and represent more clinical relevance than subcutaneous model. Here, we described how to create the murine orthotopic pancreatic cancer model.
Autonomous self-burying seed carriers for aerial seeding
Authors: Luo Danli , Maheshwari Aditi , Danielescu Andreea , Li Jiaji , Yang Yue , Tao Ye , Sun Lingyun , Patel Dinesh K. , Wang Guanyun , Yang Shu , Zhang Teng , Yao Lining 
Published: May 2024

Abstract

Aerial seeding can quickly cover large and physically inaccessible areas to improve soil quality and scavenge residual nitrogen in agriculture, and for postfire reforestation and wildland restoration. However, it suffers from low germination rates, due to the direct exposure of unburied seeds to harsh sunlight, wind and granivorous birds, as well as undesirable air humidity and temperature. Here, inspired by Erodium seeds, we design and fabricate self-drilling seed carriers, turning wood veneer into highly stiff (about 4.9 GPa when dry, and about 1.3 GPa when wet) and hygromorphic bending or coiling actuators with an extremely large bending curvature (1,854 m-1), 45 times larger than the values in the literature. Our three-tailed carrier has an 80% drilling success rate on flat land after two triggering cycles, due to the beneficial resting angle (25°–30°) of its tail anchoring, whereas the natural Erodium seed’s success rate is 0%. Our carriers can carry payloads of various sizes and contents including biofertilizers and plant seeds as large as those of whitebark pine, which are about 11 mm in length and about 72 mg. We compare data from experiments and numerical simulation to elucidate the curvature transformation and actuation mechanisms to guide the design and optimization of the seed carriers. Our system will improve the effectiveness of aerial seeding to relieve agricultural and environmental stresses, and has potential applications in energy harvesting, soft robotics and sustainable buildings.
Oxidative release of glycans from carbohydrate-conjugated vaccine
Authors: Wang Szu-Wen 
Published: May 2024

Abstract

This protocol provides a oxidative method to release glycans from glycoconjugates which was conjugated using p-nitrophenyl ester homobifunctional linker. The advantages of this protocol are its low costs and easy way to purified glycans from complicated samples, such as cell lysate, for glycomic analyses by LC-MS/MS.
A systematic review of pharmacogenetic guided opioid therapy for pain.
Authors: Jethwa Sneha 
Published: May 2024

Abstract

Title
A systematic review of pharmacogenetic guided opioid therapy for pain.
Authors
Sneha Jethwa
Contact:
Sj648@cam.ac.uk
University of Cambridge
Contributions
Dr Kenneth Langlands
Rationale
Genetic polymorphisms have been shown to have a role in the variability in response to analgesics. Clinical Pharmacogenetics Implementation Consortium (CPIC) has issued guidelines that support pharmacogenetic testing for opioid therapy, including the CYP2D6, OPRM1, and COMT genes (Crews et al., 2021). There is a need to determine if pharmacogenetic-guided opioid prescribing leads to improved clinical outcomes using data from clinical trials and whether healthcare providers could benefit from using these tests as part of routine care.
Objectives
1) Determine if pharmacogenetic guided opioid prescribing improves clinical outcomes.
2) Determine if pharmacogenetic tests reduce adverse effects when prescribing opioid therapy.
3) Identify gaps in research and provide recommendations for future research.
Method
A systematic literature review was carried in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines 2020. The following databases were searched: Embase, MEDLINE, Cochrane Central Register of Controlled Trials and Web of Science. The search results were reported in accordance with the PRISMA-S checklist
1D-CNN-based Audio Tampering Detection Using ENF Signals
Authors: Shen Xingfa 
Published: May 2024

Abstract

The extensive adoption of digital audio recording has revolutionized its application in digital forensics, particularly in civil litigation and criminal prosecution. Electric Network Frequency (ENF) has emerged as a reliable technique in the field of audio forensics. However, the absence of comprehensive ENF reference datasets limits current ENF-based methods. To address this, this study introduces ATD, a blind audio forensics framework based on a One-Dimensional Convolutional Neural Network (1D-CNN) model. ATD can identify phase mutations and waveform discontinuities within the tampered ENF signal, without relying on an ENF reference database. To enhance feature extraction, the framework incorporates characteristics of the fundamental harmonics of ENF signals. In addition, a denoising method termed ENF Noise Reduction (ENR) based on the Variational Mode Decomposition (VMD) and Robust Filtering Algorithm (RFA) is proposed to reduce the impact of external noise on embedded Electric Network Frequency signals. This study investigates three distinct types of audio tampering—deletion, insertion, and replacement—culminating in the design of binary-class tampering detection scenarios and four-class tampering detection scenarios tailored to these tampering types. ATD achieves a tampering detection accuracy of over 93% in the four-class scenario and exceeds 96% in the binary-class scenario. The effectiveness, efficiency, adaptability, and robustness of ATD in the two and four classification scenarios have been confirmed by extensive experiments.
Population structure analysis of emmer wheat (Triticum dicoccum Schrank) germplasm conserved in National Genebank of India using SSR markers
Authors: Tanwar Jatin , Tyagi Sandhya , Sharma Shivani , Jakhar Preeti , Kumar Gaurav , Jacob Sherry R , Singh Amit Kumar , Jha Shailendra K , Kumari Jyoti 
Published: May 2024

Abstract

Knowledge of genetic diversity of crop germplasm is essential for their utilization in breeding programme. Emmer wheat germplasm received less attention for exploring its genetic diversity towards enhancing utilization. Agro-morphological characterization was done for 192 emmer wheat accessions during rabi season 2019-20 and subsequently, 96 accessions were selected for morphological and molecular diversity analysis during 2020-21. We estimated genetic diversity and population structure of 96 diverse dicoccum genotypes conserved in national genebank of India using 56 microsatellite (SSR) markers. The number of alleles per locus ranged from 1 to 6 with an average of 1.68 alleles. A total of 93 alleles were detected with the highest PIC value (0.9912) observed for Xcfd20 marker. Based on ‘STRUCTURE’ analysis, 96 dicoccum accession were divided into two sub-populations. The analysis of molecular variance (AMOVA) revealed that genetic differentiation among subpopulations was low and within subpopulations was high. A cluster analysis based on the Jaccard’s dissimilarity index identified two clusters which was in congruence with population structure. Indigenous and exotic collections were categorized into distinct sub-clusters within the same cluster with some overlapping suggesting limited genomic differentiation between these collections from different geographical regions. Based on the allelic information and cluster analysis, cultivated emmer wheat showed low genetic diversity and narrow genetic base. The low genetic diversity in emmer wheat accessions may be due to limited cultivation in small pockets that emphasized a need to broaden the genetic base of emmer wheat genetic resources for enhancing its utilization.
AutoML Platform for Comparative Analysis of Machine Learning Models
Authors: Vinod Pal Sonam , Balasaheb Wagh Shraddha , Pandurang Yadav Mandar , Ravindra Yadgude Samrudhi , Sayyad S F 
Published: May 2024

Abstract

Automated Machine Learning (AutoML) platforms have emerged as indispensable tools in facilitating efficient algorithm selection for diverse machine learning tasks. In this study, we introduce a novel AutoML platform designed to empower users with seamless comparative analysis of machine learning algorithms. Our platform offers a user-friendly interface, guiding users through the process of uploading datasets, selecting algorithms, and evaluating performance metrics. Leveraging automation and in-depth analysis, users can effortlessly compare the performance of two selected algorithms, gaining insights into their data-driven projects. Through visualization tools and explainability mechanisms, our platform aids users in making informed decisions for optimal algorithm selection. By addressing the complexities of algorithm selection and enhancing accessibility, our AutoML platform contributes to advancing data-driven decision-making across various domains.
Psychometric Properties of the Coercion Experience Scale in Patients with Mental Disorders in Iran
Authors: Karimi Kimia , Gardashkhani Sevda , Belil Fatemeh Ebrahimi 
Published: May 2024

Abstract

Background
People with mental disorders are a vulnerable part of society, and it is essential to defend the rights of these patients. The use of threats and coercion s in mental care is a controversial and important issue for research. Therefore, there is a need for a tool that health workers can also use to measure the experience of coercion in mental patients. The present study was conducted with the aim of investigating the psychometric properties of the Coercion Experience Scale among patients admitted to psychiatric departments in Iran.
Methods
This study is a methodological study that examines the psychometric properties of the Coercion Experience Scale in 264 psychiatric patients in psychiatric departments. The instrument's psychometric properties were examined to determine content validity, construct validity (factor analysis), and internal consistency.
Results
The results showed the confirmation of the 34-item and 7-factor model of The Coercion Experience Scale in mentally ill patients in Iran, which explained 63.71% of the total variance. The overall reliability of the tool was also obtained with the internal consistency method of 0.92.
Conclusion
The appropriate model of the Coercion Experience Scale in Iranian society is a scale with 34 items and 7 factors with the best conditions in terms of factorial structure and internal consistency, and it can be used as a screening tool for mental patients in Iran who need support after coercive and threatening interventions to avoid the consequences of traumatic experiences.
Expression and prognosis of NR3C1 in uterine corpus endometrial carcinoma based on multiple datasets
Authors: Shen Yahui , Lu Yanping 
Published: May 2024

Abstract

Uterine corpus endometrial carcinoma (UCEC), a prevalent malignancy in the female reproductive system, has witnessed a 30% increase in recent year. Recognizing the significance of early treatment in reducing patient mortality, the identification of potential biomarkers for UCEC plays a crucial role in early diagnosis. This study was to identify key genes associated with UCEC utilizing the Gene Expression Omnibus (GEO) database, followed by validating their prognostic value across multiple databases. Analysis of four UCEC databases (GSE17025, GSE36389, GSE63678, GSE115810) yielded 72 co-expressed genes. KEGG and GO enrichment analyses revealed their involvement in physiological processes such as transcriptional misregulation in cancer. Constructing a Protein-Protein Interaction (PPI) network for these 72 genes, the top 10 genes with significant interactions were identified. Survival regression analysis highlighted NR3C1 as the gene with a substantial impact on UCEC prognostic outcomes. Differential expression analysis indicated lower expression of NR3C1 in UCEC compared to normal endometrial tissue. Cox regression analysis, performed on clinical datasets of UCEC patients, identified clinical stage III, clinical stage IV, age, and NR3C1 as independent prognostic factors influencing UCEC outcomes. The LinkedOmics online database revealed the top 50 positively and negatively correlated genes with NR3C1 in UCEC. Subsequent investigations into the relationship between NR3C1 and tumor-infiltrating immune cells were conducted using R software. Gene set enrichment analysis (GSEA) provided insights into NR3C1-related genes, showing enrichment in processes such as Ribosome, Oxidative phosphorylation in UCEC. Collectively, these comprehensive analyses suggest that NR3C1 may serve as a potential biomarker indicating the prognosis of UCEC.
Traffic Aware Dynamic Beamforming Antenna Design For 5G Communication
Authors: Imon Hasibul Islam , Rahman Md. Asikur , Reza Md. Mahfuz , Karmaker Amit , Hossain Md. Abir 
Published: May 2024

Abstract

Dynamic beamforming is a wireless communication technique that enhances signal transmission and reception using multiple antennas to focus radio frequency energy towards specific directions or devices. Dynamic beamforming faces several challenges as mobility, signal interference, beam misalignment, beam training overhead, and signal traffic management. In this research work, an Advanced Optimized Algorithm (AOA) for beam-forming is proposed after a comprehensive analysis of the performance exhibited by the least mean square (LMS) and the Adaptive gradient algorithm. The weights of the antenna array are initiated and updated by the Advanced optimized algorithm, which involves moving in the direction of the negative gradient of the error signal. This optimization method significantly improves the array factor and the weighted value compared to the LMS and Ada-Grad algorithm, which reduce the processor burden and power consumption during the beamforming process. The outcomes of the experiments and analysis reveal that the proposed Advanced Optimized Algorithm is effective in enhancing the overall performance of beamforming patterns in the desired direction and can be used to resolve the issues of signal interference by employing complex weights for 5G antenna design. The proposed method demonstrates the suitability for high-speed, reliable real-time data communication, along with superiority for signal strength over the LMS and Ada-Grad algorithms.
The notable outcomes of modified thiotepa-based conditioning followed by autologous stem cell transplantation in primary central nervous system lymphomas: A real-life pilot study
Authors: Li Yan , Li Sen , Bao Fang , Ma Lan , Zhao Wei , Yang Ping , Dong Fei , Wang Jijun , Jing Hongmei 
Published: May 2024

Abstract

High-dose chemotherapy followed by autologous stem cell transplantation (HDC–ASCT) is a promising approach for patients with primary central nervous system lymphoma (PCNSL). Encouraging results have been reported with thiotepa-based conditioning; however, there is currently no consensus on the optimal conditioning regimens. To improve the tolerance and efficacy of ASCT with thiotepa-based conditioning, this retrospective, single-arm, pilot study was conducted, including 12 PCNSL patients who received ASCT with modified thiotepa-based conditioning regimens. It was found that 6 patients received ASCT as a first-line consolidation in complete response (CR)/partial response (PR) state, and 6 cases underwent salvage treatment. Among the patients, 7 (58.3%) received the mTBC conditioning regimen, 4 (33.3%) received TT-Bu, and one patient was incorporated with chimeric antigen receptor T-cell (CAR-T) cell infusion with the TT-Cy regimen. All patients achieved sustained neutrophil recovery within a median of 9 (range, 7–12) days and platelet engraftment within a median of 10 (range, 6–12) days. Furthermore, all patients were in CR status at the initial efficacy evaluation following ASCT. The main complications during hospitalization were febrile neutropenia (83.3%) and diarrhea grade 3 (50.0%). No transplantation- related mortality occurred. Maintenance therapy post-ASCT was administered in 11 cases, demonstrating its effectiveness and favorable tolerability. The estimated 1- and 3-year progression-free survival (PFS) following ASCT were 80.0% and 53.3%, respectively, while the estimated 1-and 3-year overall survival (OS) were both 100%. This study presented the modified thiotepa-based conditioning regimens and confirmed their safety and efficacy with ASCT for PCNSL patients.