bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVEKTIVITAS PERENDAMAN KELUBI (ELEIODOXA CONFERTA) TERHADAP KADAR MIKROBA DAN KALSIUM TEPUNG CANGKANG TELUR
Authors: Gaol Susan Lumban , Wijinindyah Ayutha , Mudhita Ida ketut 
Published: June 2024

Tingkat limbah dari cangkang telur semakin meningkat. Limbah cangkang telur perlu di manfaatkan menjadi tepung cangkang yang banyak mengandung kalsium dan bisa menurunkan tingkat pembuangan limbah di Indonesia. Cangkang telur merupakan sumber kalsium yang ketersediaannya melimpah namun belum banyak dimanfaatkan. Tanaman Buah kelubi merupakan salah satu jenis buah rasa asam yang dapat ditemukan di daerah tertentu, seperti Sumatera di daerah Kalimantan. Senyawa, flavonoid, saponin, dan alkaloid dilaporkan terkandung dalam buah Eleiodoxa conferta Kelubi. Tujuan dari penelitian ini adalah untuk mengetahui kandungan extrak air buah kelubi terhadap kadar mikroba dan kalsium tepung cangkang telur. Metode yang digunakan dalam penelitian ini uji bakteri escherichia coli dan salmonella sp menggunakan metode MPN (Most Probable Number). Sedangkan uji kadar kalsium Empat perlakuan tiga ulangan uji kalsium, perendaman 3 jam, perendaman 4 jam, perendaman 5 jam dan perendaman tanpa campuran air kelubi. Hasil penelitian menunjukkan terhadap kadar kalsium bahwa semakin tinggi pemberian air buah kelubi maka kadar Ca tepung cangkang semakin meningkat. Namun uji kadar mikroba tidak memberikan efektivitas yang berbeda dalam hasil tersebut tidak ditemukannya bakteri Salmonella sp dan Escherichia Coli artinya dalam penambahan air kelubi dapat memberikan efek yang baik terhadap kadar Ca dan tepung cangkang aman dikonsumsi dengan perendama suhu ruang. Kata kunci: Air Kelubi (Eleiodoxa conferta), mikroba, cangkang telur
The Effect of Giving Liquid Organic Fertilizer Made from Cow Urine Enriched by Agricultural Symbiotic Microbes on the Production of Taiwan Grass (Pennisetum purpureum Cv. Mott)
Authors: Mudhita Ida Ketut , Saprudin  , Mulyadi Dedi , Nurlatipah Siti 
Published: June 2024

This research aims to determine the effect of adding liquid organic fertilizer (POC) made from cow urine and agricultural symbiotic microbes on the growth and production of Taiwan grass (Pennisetum purpureum Cv. Mott). The research location is Natai Raya Village, Kumai District, West Kotawaringin Regency. The research method used a unidirectional Randomized Block Design (RAK) with 3 fertilizer treatments applied to Taiwanese grass with 6 replication plots. Treatment consists of: P1 using chemical fertilizer (PK) 100% NPK 200 kg/ha (40 g/plant) or P2 using PK 100%+25% POC (100 ml/plant), and P3 using PK 100%+50 % POC (200 ml/plant). The parameters observed were: plant height, stem diameter, number of tillers, leaf length, fresh weight production (BS), dry matter production (DW) and organic matter production (BO). The results of the study showed that there was a significant increase (P<0.05) with the addition of POC on the growth and production of Taiwan grass. Plant height increased significantly, the highest at P3 was 91.6 cm, an increase of 32.2% compared to P1 of 69.3 cm, at P2 it increased by 16.1%. The largest stem diameter in P3 was 2.18 cm, an increase of 29.9% compared to P1 of 1.68 cm, P2 increased 13.7%. The highest number of offspring at P3 18.56 increased 45.5% compared to P1 12.75, P2 increased 24.9%. The length of the longest leaf on P3 was 77.46 cm, an increase of 40.5% compared to P1 of 55.13 cm, P2 increased 34.55%. The highest BS production was at P3 28,550 tons/ha, an increase of 22.37% compared to P1 23.33 tons/ha, P2 increased 9.74%. BK production was highest at P3 13.38 tonnes/ha, an increase of 25.6% compared to P1 10.62 tonnes/ha, P2 increased 12.5%. The highest BO production was at P3 7,208 tonnes/ha, an increase of 30.62% compared to P1 5.51 tonnes/ha, P2 increased 15.92%. The conclusion of this research is that the higher the dose of liquid organic fertilizer made from cow urine, the higher the growth and production of Taiwanese grass. The optimal fertilizer dose is 100% chemical fertilizer treatment with added liquid organic fertilizer made from 50% cow urine.

Keywords : Chemical fertilizer; liquid organic fertilizer; cow urine; agricultural symbiotic microbes; growth and production; Taiwan grass
Chemical Analysis of Chicken Sempol for Food Safety Program in Karanganyar Regency
Authors: Wijayanti Desna Ayu 
Published: June 2024

This aims study to evaluate chemical composition of chicken sempol in Karanganyar Regency. The sampling location of the research was carried out at sempol A sellers (Karanganyar Square area), sempol B (Pujasera Streetfood area), sempol C (Jl. Lawu area). The research method used a Complete Randomized Design (RAL) with 3 treatments and 4 repeats. Sampling was carried out by nonprobability sampling and research method with descriptive quantitative analysis. Data analysis in this study used Analysis of Variance (ANOVA). The findings demonstrate significant (P<0.05) variations in protein content, water content, carbohydrate content, fat content and boraks and formalin analysis the chicken sempol. The highest chemical content of sempol is carbohydrate which is 51,12% in sempol A. The highest water content in sempol A (48.73%), the highest protein content in sempol C (10.76%), carbohydrate content A (51.12%), the highest fat content in sempol B (11.87%). Chemical quality tests reveal protein content at 9.59%, water content at 47.77%, carbohydrate content at 47.17%, fat content at 9.21%, the result and discussion of boraks and formalin on sempols is negative (-). Sempol ayam at traders in Karanganyar has different chemical characteristics. This study concludes that chicken sempol with chemical quality can provide information on the quality of food or processed products that are good for consumers so as to increase the nutritional value of food products.
Keywords : chicken sempol ,chemical analysis, karanganyar regency, chemical characteristics, chemical composition
Pelatihan Pendirian dan Tata Kelola Bank Desa Untuk Pengembangan Ekonomi dan Kesejahteraan Masyarakat Desa Sumberdem
Authors: Anas M. Yusuf Azwar , Manan Yuliyanti M. 
Published: June 2024

Pengembangan pedesaan dan keberlanjutan keuangan mikro menjadi fokus utama untuk mengatasi kesenjangan antara perkotaan dan pedesaan. Berdasarkan Rencana Pembangunan Jangka Menengah Nasional (RPJMN) 2020–2024, Indonesia memprioritaskan pembangunan pedesaan dengan alokasi dana desa dari APBN sejak tahun 2015. Pelatihan pendirian dan tata kelola Bank Desa merupakan langkah awal pendirian bank desa serta meningkatkan inklusi keuangan di wilayah pedesaan. Metode pelaksanaan pelatihan mencakup identifikasi masalah, penyusunan materi pelatihan, pelaksanaan pelatihan, dan evaluasi keberlanjutan. Kegiatan pelatihan yang diadakan di Desa Sumberdem melibatkan berbagai pihak, seperti tokoh masyarakat, perangkat desa, pengurus BUMDES, dan mahasiswa KKN UNIRA Malang. Materi pelatihan meliputi perencanaan bisnis, proses pendirian bank desa, tata kelola yang baik, serta produk dan layanan yang dapat ditawarkan oleh Bank Desa. Diskusi interaktif dan simulasi digunakan untuk memberikan pemahaman yang komprehensif kepada peserta. Program pendampingan lanjutan akan dilakukan untuk membantu implementasi pengetahuan yang diperoleh dalam praktik nyata.
Meningkatkan Aktivitas dan Hasil Belajar Matematika Siswa SMP pada Materi Bangun Ruang Sisi Lengkung Melalui Penerapan Model Pembelajaran RME
Authors: Sallao Yulianti 
Published: June 2024

Matematika merupakan mata pelajaran yang menitikberatkan pada kemampuan Abstrak, atau kompetensi daya nalar. Karena kemampuan di lapangan rata-rata siswa untuk memahami materi abstrak masih rendah, hal ini dibuktikan dengan hasil belajar siswa di kelas IX sebelum penerapan model pembelajaran RME masih rendah yaitu 50% siswa yang hasil belajarnya mencapai di atas KKM. Untuk mengubah pandangan tersebut diperlukan suatu cara yang bisa membuat siswa tertarik untuk mempelajari matematika. Belajar merupakan proses yang membuat seseorang mengalami perubahan tingkah laku baik dalam bentuk pengetahuan maupun sikap sebagai hasil dari pengalaman yang diperolehnya. Pembelajaran matematika harus dapat dikemas dalam bentuk yang menyenangkan dan melibatkan semua siswa secara aktif, sehingga siswa memperoleh sendiri pengetahuan yang harus dimilikinya. Penelitian ini dilaksanakan dalam 2 siklus, masing-masing siklus terdiri atas tahap Perencanaan, Tindakan, Pengamatan, Refleksi. Sedangkan pendekatan pembelajaran dalam penelitian ini menggunakan model pembelajaran Realistics Mathematic Education (RME). Kriteria keberhasilan penelitian tindakan ini penulis tentukan sebagai berikut: Siswa dinyatakan berhasil dalam pembelajaran yang peneliti lakukan jika: (1) Nilai hasil test mencapai ≥ 60 (KKM=60), (2) Nilai afektif dari hasil observasi terhadap proses pembelajaran mencapai ≥ 13, Dari hasil peneleitian diperoleh gambaran, siswa memperoleh nilai hasil tes tulis ≥ 60 pada siklus I sebanyak 29 siswa (85,29 %), siklus II sebanyak 33 siswa (97,06 %) .Dari hasil observasi diperoleh gambaran adanya peningkatan aktivitas siswa dalam pembelajaran yaitu pada siklus 1 siswa yang aktif dan sangat aktif sebanyak 16 siswa (47,06%), siklus II sebanyak 30 siswa (88,24 %). Dengan demikian pembelajaran materi bangun ruang sisi lengkung dengan penerapan model pembelajaran RME dapat meningkatkan hasil belajar siswa kelas IX SMP Negeri 1 Makimi dengan meningkatnya hasil belajar dari siklus I sampai dengan. Siklus II hasilnya meningkat secara signifikan dengan kata lain anak yang mengalami kesulitan belajar berkurang, sedangkan dari hasil observasi yang diperoleh peningkatan aktivitas, siswa terlibat aktif dalam proses pembelajaran serta mampu memacu siswa untuk belajar mengkonstruksi sendiri materi pelajaran yang sedang dipelajari dan bila mengalami kesulitan siswa dibantu teman sekelompoknya yang terlebih dahulu memahami materi yang dipelajari dan bila dalam suatu kelompok tidak ada yang bisa menyelesaikan kesulitan yang dihadapi langsung bertanya pada guru.
From Costume Romps to Queer Milestones: Adaptation, Collaboration, Queerness and Modernism in the ‘Long New Wave’ of Richardson, Schlesinger and Reisz
Authors: Monk Claire 
Published: June 2024

The post-New Wave films and trajectories of the key British New Wave directors remain under-analysed terrain, both in terms of their potential relevance for interrogating how we understand the British New Wave itself and for the terms in which we might conceptualise a ‘Long’ New Wave. This article departs from persisting auteurist approaches to consider the post-New Wave oeuvres and careers of these directors collectively, in terms which foreground the importance of collaborations and networks rather than individual authorship and seek to decentre, denaturalise and potentially dislodge their pre-eminent association with specifically Northern, British, social realism and its presumed legacies. I argue for the importance of a cluster of less-analysed areas of intersection and development which emerge across the eclectic film-making careers of Tony Richardson and John Schlesinger (and, to a lesser extent, Karel Reisz) in the immediate post-New Wave decade from the 1963 success of Richardson's Tom Jones to the early 1970s. My discussion pivots on two commonalities: during this time, all three directors contributed significantly and plurally to innovations and advances in genre and representation across two areas distinct from British Northern working-class realism: historical/costume film genres, and queer representation. An approach which centres the (broadly defined) queer elements in these directors’ post-New Wave oeuvres – intersecting at times with their equally undervalued contribution to ‘pre-heritage’ period cinema – reveals the ‘Long’ New Wave as substantially a cinema of adaptation, collaboration and queerness which encompassed important, near-forgotten, international projects as well as modernist influences and, in Schlesinger's Sunday Bloody Sunday, a significant advance in realist queer representation.
Key drivers of vulnerability to rainfall flooding in New Orleans
Authors: Kane Patrick Bodilly , Tebyanian Nastaran , Gilles Daniel , McMann Brett , Fischbach Jordan R. 
Published: June 2024

IntroductionFuture urban stormwater flood risk is determined by the confluence of both climate-driven changes in precipitation patterns and the effectiveness of flood mitigation systems, such as urban drainage and pump systems. This is especially true in coastal cities protected by levee systems like New Orleans, where even present-day rainfall would be enough to cause serious flooding in the absence of extensive stormwater drainage and pumping. However, while the uncertainties associated with climate change have been well studied, uncertainties in infrastructure performance and operation have received less attention.MethodsWe investigated how these interrelated sets of uncertainties drive flood risk in New Orleans using a Robust Decision Making (RDM) approach. RDM is a framework for Decision Making Under Deep Uncertainty (DMDU) that leverages simulation models to facilitate exploration across many possible futures and the identification of decision-relevant scenarios. For our work, we leveraged a detailed Storm Water Management Model (SWMM) representation of the New Orleans urban stormwater management system to examine flood depths across the city when faced with different levels of future precipitation, sea-level rise, drainage pipe obstruction, and pumping system failure. We also estimated direct flood damage for each neighborhood in the city for this scenario ensemble. These damage estimates were then subjected to vulnerability analysis using scenario discovery—a technique designed to determine which combinations of uncertainties are most stressful to the system in terms of an outcome of interest (excess flood damage).ResultsOur results suggest that key drivers of vulnerability depend on geographic scale. Specifically, we find that possible climate-driven precipitation increases are the most important determinant of vulnerability at the citywide level. However, for some individual neighborhoods, infrastructure operation challenges under present day conditions are a more significant driver of vulnerability than possible climate-driven precipitation increases.
Apolipoprotein A-I levels in the survival of patients with colorectal cancer: a retrospective study
Authors: Xie Hailun , Wei Lishuang , Wang Qiwen , Tang Shuangyi , Gan Jialiang 
Published: June 2024

BackgroundAbnormal lipid levels have been associated with cancer incidence and progression. However, limited studies have investigated the relationship between apolipoprotein A-I (ApoA-I) and colorectal cancer (CRC). This study assessed the significance of ApoA-I levels in progression-free survival (PFS) and overall survival (OS) of patients with CRC.MethodsSurvival curves were compared using Kaplan–Meier analysis, while the predictive values of various lipid indicators in CRC prognosis were evaluated based on receiver operating characteristic curves. The factors influencing PFS and OS in patients with CRC were analyzed using Cox proportional hazards regression models. Finally, the relationship between ApoA-I level and disease recurrence was investigated through logistic regression analysis. The optimal Apo-I level was determined through maximally selected rank statistics.ResultsUsing the optimal ApoA-I cutoff value (0.9 g/L), the 1,270 patients with CRC were categorized into low (&lt; 0.9 g/L, 275 cases) and high (≥0.9 g/L, 995 cases) ApoA-I groups. Compared with other lipid indicators, ApoA-I demonstrated superior predictive accuracy. The high ApoA-I group exhibited significantly higher survival rates than the low ApoA-I group (PFS, 64.8% vs. 45.2%, P &lt; 0.001; OS, 66.1% vs. 48.6%, P &lt; 0.001). Each one-standard-deviation increase in ApoA-I level was related to a 12.0% decrease in PFS risk (hazard ratio [HR] 0.880; 95% confidence interval [CI], 0.801–0.968; P = 0.009) and an 11.2% decrease in OS risk (HR 0.888; 95%CI, 0.806–0.978; P = 0.015). Logistic regression analysis revealed that patients with low ApoA-I had a 32.5% increased risk of disease recurrence (odds ratio [OR] 0.675; 95%CI, 0.481–0.946; P = 0.0225) compared with those with high ApoA-I. PFS/OS nomograms based on ApoA-I demonstrated excellent prognostic prediction accuracy.ConclusionsSerum ApoA-I level may be a valuable and non-invasive tool for predicting PFS and OS in patients with CRC.
Distinct small RNAs are expressed at different stages of Phytophthora capsici and play important roles in development and pathogenesis
Authors: Zhong Shan , Zhang Sicong , Zheng Yang , Zhang Qinghua , Liu Fangmin , Wang Zhiwen , Liu Xili 
Published: June 2024

Small RNAs (sRNAs) are important non-coding RNA regulators that play key roles in the development and pathogenesis of plant pathogens, as well as in other biological processes. However, whether these abundant and varying sRNAs are involved in Phytophthora development or infection remains enigmatic. In this study, sRNA sequencing of 4 asexual stages of Phytophthora capsici (P. capsici), namely, as mycelia (HY), sporangia (SP), zoospores (ZO), cysts (CY), and pepper infected with P. capsici (IN), were performed, followed by sRNA analysis, microRNA (miRNA) identification, and miRNA target prediction. sRNAs were mainly distributed at 25–26 nt in HY, SP, and ZO but distributed at 18–34 nt in CY and IN. 92, 42, 176, 39, and 148 known miRNAs and 15, 19, 54, 13, and 1 novel miRNA were identified in HY, SP, ZO, CY, and IN, respectively. It was found that the expression profiles of known miRNAs vary greatly at different stages and could be divided into 4 categories. Novel miRNAs mostly belong to part I. Gene ontology (GO) analysis of known miRNA-targeting genes showed that they are involved in the catalytic activity pathway, binding function, and other biological processes. Kyoto Encyclopedia of Gene and Genome (KEGG) analysis of novel miRNA-targeting genes showed that they are involved in the lysine degradation pathway. The expression of candidate miRNAs was validated using quantitative reverse transcription–polymerase chain reaction (qRT–PCR), and miRNAs were downregulated in PcDCL1 or PcAGO1 mutants. To further explore the function of the detected miRNAs, the precursor of a novel miRNA, miR91, was knockout by CRISPR-Cas9, the mutants displayed decreased mycelial growth, sporangia production, and zoospore production. It was found that 503142 (Inositol polyphosphate 5-phosphatase and related proteins) can be predicted as a target of miR91, and the interaction between miR91 and 503142 was verified using the tobacco transient expression system. Overall, our results indicate that the diverse and differentially expressed sRNAs are involved in the development and pathogenesis of P. capsici.
Decoding the immune landscape: a comprehensive analysis of immune-associated biomarkers in cervical carcinoma and their implications for immunotherapy strategies
Authors: Wang Le , Liu Huatian , Feng Yue , Liu Xueting , Wang Yuan , Liu Yujie , Li Hao , Zhang Yunyan 
Published: June 2024

Background and aimsCervical cancer, a prevalent gynecological malignant tumor, poses a significant threat to women’s health and lives. Immune checkpoint inhibitor (ICI) therapy has emerged as a promising avenue for treating cervical cancer. For patients with persistent or recurrent metastatic cervical cancer, If the sequence of dead receptor ligand-1 (PD-L1) is positive, ICI show significant clinical efficacy. PD-L1 expression serves as a valuable biomarker for assessing ICI therapeutic efficacy. However, the complex tumor immune microenvironment (TIME), encompassing immune cell composition and tumor-infiltrating lymphocyte (TIL) status, also exerts a profound influence on tumor immunity and prognosis. Given the remarkable strides made by ICI treatments in improving the survival rates of cervical cancer patients, it becomes essential to identify a comprehensive biomarker that integrates various TIME aspects to enhance the effectiveness of ICI treatment. Therefore, the quest for biomarkers linked to multiple facets of TIME in cervical cancer is a vital pursuit.MethodsIn this study, we have developed an Immune-Associated Gene Prognostic Index (IRGPI) with remarkable prognostic value specifically for cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). The Cancer Genome Atlas CESC dataset (n = 305) was meticulously analyzed to pinpoint key immune-related genes via weighted gene co-expression network analysis and differential gene expression assays. Subsequently, we employed Cox regression analysis to construct the IRGPI. Furthermore, the composition of immune cells and TIL status were examined using CIBERSORT and TIDE. Tumor expression of Epigen, LCN10, and P73 were determined with immunohistochemistry.ResultsThe resulting IRGPI, composed of EPGN, LCN10, and TP73 genes, displayed a strong negative correlation with patient survival. The discovery was validated with a patient cohort from our hospital. The IRGPI not only predicts the composition of immune cell subtypes such as Macrophages M1, NK cells, Mast cells, Plasma cells, Neutrophils, Dendritic cells, T cells CD8, and T cells CD4 within CESC, but also indicates TIL exclusion, dysfunction, and PD-1 and PD-L1 expression. Therefore, the IRGPI emerges as a promising biomarker not only for prognostic assessment but also for characterizing multiple immune features in CESC. Additionally, our results underscored the significant associations between the IRGPI and immune cell composition, TIL exclusion, and dysfunction, along with PD-1 and PD-L1 expression in the TIME.ConclusionConsequently, the IRGPI stands out as a biomarker intimately connected to both the survival and TIME status of CESC patients, offering potential insights into immunotherapy strategies for CESC.