bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ring‐Opening Copolymerization of 2,2‐Dimethyltrimethylene Carbonate and ε‐Caprolactone Using Rare Earth Aryloxides Substituted by Various Alkyl Groups
Authors: Zhang Lifang , Wang Yan , Shen Lijuan , Zhang Ting 
Published: July 2010

AbstractA variety of single component rare earth aryloxides substituted by various alkyl groups [Ln(OAr)3] such as methyl, isopropyl, tert‐butyl have been surveyed in the ring‐opening copolymerization of 2,2‐dimethyltrimethylene carbonate (DTC) and ε‐caprolactone (ε‐CL). It was worthwhile to note that activity of the catalyst varied with both the ligands' structure and the number of alkyl groups on phenyl ring. The stronger ability of electron‐donation of alkyl groups on phenyl ring, and the more numbers of alkyl groups on phenyl ring, the higher catalytic activity. The experimental results show that lanthanum tris(2,4,6‐tri‐tert‐butylphenolate) [La(OTTBP)3] exhibits highest activity in all lanthanum aryloxides. 1H NMR spectral data of copolymer obtained showed that the polymerization mechanism is in agreement with the coordination insertion mechanism.
Synthesis and Functional Properties of Symmetrically Naphthyl‐Based Oligoarylenes with High Glass‐Transition Temperatures
Authors: Zhang Xiaoling , Sun Kang , Liu Yurong , Xiong Mojun , Xia Pingfang , Li Zhonghui , Cao Zijian 
Published: July 2010

AbstractSymmetrically naphthyl‐based π‐conjugated oligoarylenes, OPP(4)Ph‐TNp, OPP(4)An‐TNp and OPP(4)OX‐TNp have successfully been synthesized by a divergent approach using Pd‐catalyzed Suzuki cross‐coupling reaction of diiodo‐ or dibromo‐oligoarylene and arylboronic acid as a key step. Their optical, electrochemical and thermal properties have also been characterized. These newly synthesized naphthyl‐based oligoarylenes show highly morphological (Tg 149–187°C) and thermal (Tdec 509–597°C) stabilities as well as exhibit potential applications in optoelectronic fields.
Preparation and Catalytic Performance of Carbon Nanotube Supported Palladium Catalyst
Authors: Zhang Yan , Chu Wei , Xie Lijuan , Sun Wenjing 
Published: July 2010

AbstractTwo carbon nanotube supported palladium catalysts were prepared using a chemical reduction technique (Pd/CR‐CNT) and a conventional impregnation method (Pd/CNT) respectively, and their catalytic performances for Heck reaction were investigated. The catalysts were characterized by TEM and XPS techniques and the products were characterized by 1H NMR. Research results showed that the (Pd/CR‐CNT) catalyst showed a better catalytic activity than the (Pd/CNT) catalyst, owing to better dispersion of palladium nanoparticles and stronger interaction between the active palladium species and carbon nanotube. Meanwhile, the product yield maintained 99.93% of its initial value at five‐times re‐use, compared with that at the first time use. The catalyst prepared with the chemical reduction method represented a better reusing performance.
Screening and Verification of Differentially Expressed Proteins from Pancreatic Cancer Tissue
Authors: Cui Lei , Li Fang , Zhao Qingchuan , Li Zhili 
Published: July 2010

AbstractPancreatic cancer (PC) is a devastating disease, with a mortality rate almost identical with its incidence. Biomarkers are desperately needed to improve earlier, more curable cancer diagnosis and to develop new effective therapeutic targets. In this study, differentially expressed proteins between PC and adjacent normal tissues from paired tissues of 9 patients were investigated by 2‐DE coupled to MALDI‐TOF/TOF mass spectrometry. 23 differentially expressed proteins were identified, 5 and 18 of which were up‐regulated and down‐regulated, respectively, including transcription regulators, signal transducers, antioxidant activity proteins, catalytic activity proteins and binding proteins. Carboxypeptidase B (CBPB1), trypsin‐1 (TRY1) and peroxiredoxin‐2 (PRDX2) were further confirmed by Western blot analysis. It is found that there is the significant difference for PRDX2 and TRY1 (p<0.05) compared with adjacent normal tissues. It should be noted that three proteins [lithostathine 1 beta (REG1B), serpin B6 (SPB6), glucagon (GLUC)] related to PC were first detected in this study, which may be potential biomarkers for the diagnosis and prognosis of patients with PC.
Silica‐Coated CaF2:Eu3+ Nanoparticles Functionalized with Oxalic Acid for Bio‐conjugation to BSA Proteins
Authors: Tian Yue , Hua Ruinian , Yu Jicheng , Chen Baojiu , Sun Jiashi , Cheng Lihong 
Published: July 2010

AbstractA new method for silica‐coated CaF2:Eu3+ core‐shell nanoparticles functionalized with oxalic acid for bio‐conjugation to bovine serum albumin (BSA) proteins has been developed. Moreover, CaF2:Eu3+/SiO2 core‐shell nanoparticles modified with oxalic acid are biocompatible and can be dispersed in water. As an organic functional molecule, oxalic acid is able to react with hydroxyl groups existed on the surface of SiO2 layer by esterification reaction to form carboxylic acid for further bio‐conjugation with BSA. The final products were characterized by means of X‐ray diffraction (XRD), transmission electron microscope (TEM), field‐emission scanning electron microscopy (FE‐SEM), ultraviolet (UV) spectrophotometer, infrared (IR) spectrophotometer and photoluminescence (PL) spectra. XRD result confirmed the phase purity of CaF2:10 mol% Eu3+ and CaF2:10 mol% Eu3+/SiO2 nanoparticles obtained from the quaternary reverse micelles of cetyltrimethylammonium bromide (CTAB), cyclohexane, n‐pentanol and water. Images of TEM and FE‐SEM showed that the average grain sizes of CaF2:10 mol% Eu3+/SiO2 and bio‐conjugation of CaF2:10 mol% Eu3+/SiO2 nanoparticles with BSA were about 17 nm. The patterns of UV and IR spectra showed that BSA was linked to CaF2:10 mol% Eu3+/SiO2 nanoparticles. In the emission spectrum of CaF2:10 mol% Eu3+/SiO2 conjugated by BSA nanoparticles, characteristic emission peaks of Eu3+ within the wavelength ranging from 500 to 700 nm were observed, which is corresponding to the transitions from the excited 5D0 levels to 7FJ levels. This confirmed that the Eu3+ dopant ion is located in a Ca2+ crystal site with Td symmetry. CaF2:10 mol% Eu3+/SiO2 conjugated by BSA nanoparticles remain stable in aqueous media within 15 d with pH ranging from 2 to 9. Therefore, these luminescent colloidal nanoparticles can be potentially employed as targeted fluorescent labels in biomedical research applications.
Synthesis and Characterization of a Series of New Asymmetric Salphen Mono‐ and Binuclear Metal Complexes
Authors: Li Jiayuan , Guo Liqin , Ruan Wenjuan , Zhu Zhiang 
Published: July 2010

AbstractTwo novel asymmetric salen ligands H2L1 [N‐phenyl‐N‐(2‐hydroxy‐5‐methylphenyl)‐N′‐(2‐hydroxy‐3‐meth‐ oxylphenyl)‐o‐phenyldiamine] and H2L2 [N‐phenyl‐N‐(2‐hydroxy‐5‐chlorophenyl)‐N′‐(2‐hydroxy‐3‐methoxyl‐ phenyl)‐o‐phenyldiamine] and their metal complexes MLn (M=Zn, Co, Ni, Cu; n=1, 2) have been prepared and characterized by elemental analyses, 1H NMR, ESI‐MS, FT‐IR and UV‐Vis spectra. In particular, the complex ZnL1, the binuclear monosalphen complex, was synthesized and studied in detail using 1H NMR and ESI‐MS techniques. For other metal complexes under the same reaction conditions, only mononuclear complexes were obtained. The results are relevant to both the metal ions and the structure of ligands.
Synthesis and Spectral Tuning of Novel Triphenylamine‐Based Derivatives Containing Electron Donor‐Acceptor Groups
Authors: Gao Fang , Liu Jian , Yang Long , Wang Qi , Li Hongru , Zhang Shengtao 
Published: July 2010

AbstractThis paper presents the investigation of tuning the color and photoluminescence of a range of triphenylamine‐ based derivatives with various substituent groups. The ultraviolet/visible absorption and fluorescence spectroscopy of the derivatives showed remarkable difference. The molecular geometry optimization demonstrated that the properties of the ground state and the excited state of the compounds have a close relationship with the substituent groups. Therefore, it is possible to tune the color and photoluminescence of the derivatives at molecular level. The cyclic voltammograms of these compounds were detected in methylene chloride at various scan rates. The thermal stabilities of the compounds were analyzed with the different scanning calorimetry and the thermogravimetry.
Efficient Polymer‐Supported Pd Catalysts for the Heck Reaction
Authors: Liu Yuxia , Jia Jun , Tan Haohan , Sun Yanan , Tao Jingchao 
Published: July 2010

AbstractSome efficient polymer‐supported palladium catalysts have been synthesized. Their catalytic effects were evaluated in the Heck reaction of iodobenzene with acrylates or styrene. High catalytic activities were achieved with turn over frequencies (TOF) up to 28000 and 6250, respectively. For the reaction of iodobenzene with styrene, high stereoselectivity was obtained. Additionally, the catalysts could be recovered by a simple filtration progress and can be reused for at least 5 times with a slow progressive decrease in activity.
Synthesis of [1,2,4]Oxadiazolo[4,5‐a]thiazolo[2,3‐b]pyrimidin‐9(10H)‐ones via 1,3‐Dipolar Cycloaddition of Nitrile Oxide to Thiazolo[3,2‐a]pyrimidin‐3‐one Derivatives
Authors: Li Xiaofang , Zheng Aiting , Liu Bin , Yu Xianyong , Yi Pinggui 
Published: July 2010

AbstractA new class of [1,2,4]oxadiazolo[4,5‐a]thiazolo[2,3‐b]pyrimidin‐9(10H)‐one was prepared in moderate yields by the reaction of nitrile oxide with 2‐arylmethylidene‐6,7‐dihydro‐5H‐thiazolo[3,2‐a]pyrimidin‐3‐one. The reaction site of dipolarphile is the CN of thiazolo[3,2‐a]pyrimidin‐3‐one rather than the expected CC of arylmethylidene. The structures of the products were characterized thoroughly by IR, elemental analysis, MS, and NMR analysis.
The Comparison of Two Different Electro‐Membrane Processes' Performance for Industrial Applications
Authors: Oztekin Yasemin , Yazicigil Zafer , Ata Nejla , Karadayi Neriman 
Published: July 2010

AbstractThe recovery of bases from solutions containing salt forms of potassium was studied in cells separated by commercial ion exchange membranes. For this aim, two different types of techniques were applied. In the first technique, an equimolar quantity of acid solutions and different metallic salt solutions were used as an anolyte and a catholyte, respectively, in the cell separating with anion exchange membrane (AEM). In the second technique, an equimolar quantity of acid, base solutions, and different metallic salt solutions were used as an anolyte, a catholyte, and a solution in the middle chamber of the cell, respectively, in the cell separating with cation exchange membrane (CEM) and AEM. Effects of the current, the type of the membranes, the concentrations of the solutions, and the type of solutions on the recovery of bases were investigated and both of the techniques were compared. The results of the experiments were evaluated with the Statistical Package for Social Sciences program.
Actin on DNA—An ancient and dynamic relationship
Authors: Skarp Kari‐Pekka , Vartiainen Maria K. 
Published: July 2010

AbstractIn the cytoplasm of eukaryotic cells the coordinated assembly of actin filaments drives essential cell biological processes, such as cell migration. The discovery of prokaryotic actin homologues, as well as the appreciation of the existence of nuclear actin, have expanded the scope by which the actin family is utilized in different cell types. In bacteria, actin has been implicated in DNA movement tasks, while the connection with the RNA polymerase machinery appears to exist in both prokaryotes and eukaryotes. Within the nucleus, actin has further been shown to play a role in chromatin remodeling and RNA processing, possibly acting to link these to transcription, thereby facilitating the gene expression process. The molecular mechanism by which actin exerts these newly discovered functions is still unclear, because while polymer formation seems to be required in bacteria, these species lack conventional actin‐binding proteins to regulate the process. Furthermore, although the nucleus contains a plethora of actin‐regulating factors, the polymerization status of actin within this compartment still remains unclear. General theme, however, seems to be actin's ability to interact with numerous binding partners. A common feature to the novel modes of actin utilization is the connection between actin and DNA, and here we aim to review the recent literature to explore how this connection is exploited in different contexts.
Hairy cell leukemia
Authors: Zinzani Pier Luigi , Pellegrini Cinzia , Stefoni Vittorio , Derenzini Enrico , Gandolfi Letizia , Broccoli Alessandro , Argnani Lisa , Quirini Federica , Pileri Stefano , Baccarani Michele 
Published: July 2010

AbstractBACKGROUND:Historically, the first treatment choices for hairy cell leukemia (HCL) were splenectomy and alpha‐interferon. Recently, purine analogues (pentostatin and cladribine) changed radically the treatment modality, inducing complete and durable responses in the majority of patients.METHODS:The authors analyzed the outcome of different lines of therapy in 121 HCL patients followed in their institute from 1986 to 2008, with a median follow‐up of 105 months. Patients were divided into subgroups according to the number of treatments; Group A included 121 patients who underwent a front‐line therapy, Group B patients (n =53) were treated with 2 lines, Group C patients (n = 34) with 3 lines, Group D patients (n = 17) with 4 lines, and Group E patients (n = 8) with 5 lines.RESULTS:In Group A, 92 (77%) patients obtained a complete response (CR), 23 (18%) a partial response, and the remaining 6 (5%) a minor or no response; median duration of response was 2.7 years. In Group B, 53 relapsed patients achieved a second CR rate of 73.5%; median duration of response was 2.5 years. Group C contained 34 patients in a second relapse, with a CR rate after the third line of treatment of 70.5% (median duration of response, 2.2 years). In Group D, 11 (64.7%) patients obtained a CR (median duration of response, 1.6 years), and in Group E 4 (50%) of 8 patients achieved a CR (median duration of response, 1.3 years).CONCLUSIONS:This study confirms the high risk (>40% of all patients) of retreatment of HCL patients and the need to maximize primary response. Cancer 2010. © 2010 American Cancer Society.
Effects of Pt Shell Thicknesses on the Atomic Structure of Ru–Pt Core–Shell Nanoparticles for Methanol Electrooxidation Applications
Authors: Chen Tsan‐Yao , Lin Tsang‐Lang , Luo Tzy‐Jiun Mark , Choi Yongjae , Lee Jyh‐Fu 
Published: July 2010

AbstractIn this research, core–shell electrocatalysts comprising a Ru core covered with precisely controlled 1.5–3.6 atomic layers (ALs)‐thick Pt atoms are synthesized. The sample with 1.5 ALs shows a 3.2‐fold improvement in CO‐tolerance and 2.4‐fold current enhancement at the conventional battery operation potential (I300, at 300 mV vs Ag/AgCl) during methanol oxidation as compared with conventional all‐Pt nanoparticles. The origin of the enhanced performance and the atomic structure of the core–shell nanoparticles are elucidated to be mainly dominated by the lattice strain (possibly some slight effect of heteroatomic interactions) then by the combination of ligand effects and bifunctional mechanisms when the shell crystal is thicker than 2.7 ALs.
Patterns of inner change and their relation with patient characteristics and outcome in a psychoanalytic hospitalization‐based treatment for personality disordered patients
Authors: Vermote Rudi , Lowyck Benedicte , Luyten Patrick , Verhaest Yannic , Vertommen Hans , Vandeneede Bart , Corveleyn Jozef , Peuskens Jozef 
Published: July 2010

AbstractThis study investigated whether different clusters of patients with personality disorders in a psychoanalytic hospitalization‐based treatment were associated with: (a) different changes in personality organization (PO); (b) different pre‐treatment variables; and (c) different associations between changes in PO and outcome. K‐means clustering analysis identified two clusters of patients, which showed different changes in PO and mainly differed in terms of levels of anaclitic and introjective personality features, respectively. Both clusters showed a significant decrease in symptoms and an improvement in personality functioning during treatment and at 3‐month follow‐up. Clinical implications of these findings are discussed. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Psychoanalytic hospitalization‐based treatment for patients with personality disorders is associated with changes in different aspects of personality organization such as representations of self and others, mentalization and felt safety.• Patients show different trajectories of change in personality organization, which are associated with patient characteristics such as introjective and anaclitic personality dimensions as defined by Blatt (2004).• Two identified trajectories of change during psychoanalytic hospitalization‐based treatment lead to improvement in outcome, i.e., symptom reduction and improvement in personality functioning.• Therapists should tailor treatment to individual patient characteristics in treating personality disorders.
Evolution of crystal structure of Zn:N films under high temperature
Authors: Chityuttakan C. , Wantong K. , Chatraphorn S. , Yoodee K. 
Published: July 2010

AbstractZinc‐nitrogen (Zn:N) compound thin film was prepared from a pure metallic Zn target by rf magnetron sputtering at ambient temperature under the mixture of nitrogen and argon gases with the ratio of 1:1. High temperature x‐ray diffraction (HTXRD) measurement under vacuum was used to examine the evolution of structural properties of the Zn:N film. At ambient temperature, the (002), (100), and (101) planes corresponding to Zn structure were observed while at higher temperature, the left shifts corresponding to the increase of lattice constants a and c of Zn were observed. At temperatures of 320 °C, 481 °C and 554 °C, the (222), (321) and (400) planes corresponding to Zn3N2 structure were observed with the decrease in the intensity amplitudes of the peaks belonging to the Zn structure. The results indicate the gradual transformation of the Zn3N2 phase in the Zn:N films at temperature greater than 320 °C. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Synthesis and in vitro cytotoxic activity on human anaplastic thyroid cancer cells of lipoamino acid conjugates of gemcitabine
Authors: Pignatello Rosario , Vicari Luisa , Pistarà Venerando , Musumeci Teresa , Gulisano Massimo , Puglisi Giovanni 
Published: July 2010

AbstractLipophilic derivatives of the antitumor drug gemcitabine (GEM) with the potential for improving drug loading in lipid‐based colloidal carriers, like liposomes or lipid nanoparticles, are described. GEM free base was conjugated to lipoamino acids bearing an alkyl side chain of different length, by either a carbodiimide‐assisted or an ethylchloroformiate‐assisted coupling reaction, to obtain N4‐acyl GEM derivatives. These compounds retained the same in vitro cell growth inhibitory activity of the parent drug against two lines of human anaplastic thyroid cancer cells. Stability studies suggested that the observed activity was due mainly to intact derivatives and not to released GEM. Accordingly, these amphiphilic derivatives can be proposed in a further step for the encapsulation in liposomes or lipid nanocarriers, to achieve as a final goal an improvement of the pharmacokinetics and therapeutic activity of GEM. Drug Dev Res 2010. © 2010 Wiley‐Liss, Inc.
Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded
Authors: Lyashenko Natalia , Weissenböck Martina , Sharir Amnon , Erben Reinhold G. , Minami Yasuhiro , Hartmann Christine 
Published: July 2010

AbstractRor1 is a member of the Ror‐family receptor tyrosine kinases. Ror1 is broadly expressed in various tissues and organs during mouse embryonic development. However, so far little is known about its function. The closely related family member Ror2 was shown to play a crucial role in skeletogenesis and has been shown to act as a co‐receptor for Wnt5a mediating non‐canonical Wnt‐signaling. Previously, it has been shown that during embryonic development Ror1 acts in part redundantly with Ror2 in the skeletal and cardiovascular systems. In this study, we report that loss of the orphan receptor Ror1 results in a variety of phenotypic defects within the skeletal and urogenital systems and that Ror1 mutant mice display a postnatal growth retardation phenotype. Developmental Dynamics 239:2266–2277, 2010. © 2010 Wiley‐Liss, Inc.
Ruthenium vs. Osmium Complexes as Catalysts for Atom Transfer Radical Addition Reactions
Authors: Fernández‐Zúmel Mariano A. , Kiefer Gregor , Thommes Katrin , Scopelliti Rosario , Severin Kay 
Published: July 2010

AbstractThe catalytic activity of [Cp*OsBr2(PPh3)] in conjunction with Mg has been evaluated for atom transfer radical addition (ATRA) and cyclization (ATRC) reactions. The Os complex enabled these reactions to be performed with similar efficiency as that of the analogous Ru complex [Cp*RuCl2(PPh3)]. The olefin complex [Cp*OsBr(H2C=CHPh)(PPh3)] was obtained by reduction of [Cp*OsBr2(PPh3)] with Mg in the presence of an excess of styrene, whereas an analogous Ru complex was not observed. Kinetic investigations suggest that olefin complexes of Os can form under catalytic conditions.
Mixed Disilyl‐Substituted Cyclopentadiene Derivatives and Corresponding Zirconium, Molybdenum and Tungsten Compounds
Authors: Petrisor Cristina E. , Chahboun Ghaita , El Amrani Mohamed Amin , Royo Eva , Cuenca Tomás 
Published: July 2010

AbstractThe mixed disilyl‐substituted cyclopentadiene C5H4[SiMe2(CH=CHCH3)](SiMe3) (2) has been synthesized in a one‐pot reaction by alkylation, deprotonation and silylation of C5H5(SiMe2Cl). The analogous olefin‐tethered cyclopentadiene C5H4[SiMe2(CH2CH=CH2)](SiMe3) (3) has been obtained through traditional metathesis routes from Li[C5H4(SiMe3)] and the chloroallylsilane SiMe2(CH2CH=CH2)Cl. The corresponding mixed disilyl‐substituted cyclopentadienyllithium salts Li[C5H3‐1‐SiMe2R‐3‐SiMe3] [R = CH=CHCH3 (cis+trans‐4); R = CH2CH=CH2 (5)] were used to isolate the chiral zirconium compounds [ZrX(η5‐C5H4SiMe2‐η1‐NtBu)(η5‐C5H3‐1‐SiMe2R‐3‐SiMe3)] [X = Cl, R = CH=CHCH3 (cis+trans‐6); R = CH2CH=CH2 (7); X = CH3, R = CH=CHCH3 (cis+trans‐8); R = CH2CH=CH2 (9)] and group 6 derivatives [MH(η5‐C5H3‐1‐SiMe2R‐3‐SiMe3)(CO)3] [R = CH=CHCH3, M = Mo (cis+trans‐10), M = W (cis+trans‐11); R = CH2CH=CH2, M = Mo (12) and M = W (13)], which have been fully characterized. The behaviour of metal compounds 8–13 has beenstudied and compared with that previously reported for monosubstituted alkene–silylcyclopentadienyl systems [Zr(CH3)(η5‐C5H4SiMe2‐η1‐NtBu)[(η5‐C5H4SiMe2)(CH2CH=CH2)] and [MH(η5‐C5H4SiMe2‐η1‐NtBu)[(η5‐C5H4SiMe2)(CH2CH=CH2)](M = Mo, W).
Interaction of Gold with Co‐Condensed and Grafted HMS‐SH Silica: A 29Si {1H} CP‐MAS NMR Spectroscopy, XRD, XPS and Au LIII EXAFS Study
Authors: La Parola Valeria , Longo Alessandro , Venezia Anna Maria , Spinella Alberto , Caponetti Eugenio 
Published: July 2010

AbstractHexagonal mesoporous silica (HMS) is functionalised with mercaptopropyl groups by adopting two different procedures; co‐condensation and grafting. In both cases tetraethylorthosilicate (TEOS) and 3‐mercaptopropyltriethoxysilane (3‐MPTES) are used as the silicon and sulfur precursors, respectively. The obtained materials are analysed by several techniques such as N2 sorption, TG‐DTA, XRD, SAXS and‐solid state 29Si {1H} CP‐MAS NMR spectroscopy. By taking advantage of the chemical interaction between gold and the –SH groups, the effect of the thiol addition procedure on the supporting capability of the functionalised silica is evaluated by depositing gold through the incipient wet impregnation technique. The influence of the functionalisation method on the electronic structure of gold and on its surface distribution is determined by extended X‐ray fine absorption spectra (EXAFS) of Au at the LIII edge and by X‐ray photoelectron spectroscopy (XPS).