bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gingival Cyst of the Adult: Regenerative Therapy of Associated Root Exposure. A Case Report and Literature Review
Authors: Kelsey V W. Patrick , Kalmar John R. , Tatakis Dimitris N. 
Published: December 2009

Background: The gingival cyst of the adult (GCA) is an uncommon developmental cyst of odontogenic origin most frequently seen near mandibular canines and premolars and is routinely treated with excisional biopsy. This article presents a case of a GCA treated with a combined regenerative approach and reviews the GCA literature with an emphasis on the clinical aspects of this lesion.Methods: A 54 year‐old man presented for treatment of generalized severe chronic periodontitis. Clinical examination revealed a cystic lesion in the gingiva of the mandibular canine‐premolar area. Radiographs revealed a well‐defined radiolucency in the coronal one‐third of the tooth roots. Surgical enucleation of the lesion revealed root exposure of the second premolar. Because of the anatomy of the lesion‐associated defect, regenerative treatment, using a combination of freeze‐dried bone allograft and a collagen membrane, was considered the therapeutic approach of choice.Results: The biopsy revealed histologic features consistent with a GCA. Clinical and radiographic examinations 1 year post‐surgery indicated uneventful soft tissue healing and bone fill of the initial defect. The review of the literature revealed only one other case of root exposure associated with GCA and no previous report of regenerative therapy.Conclusions: In rare instances, a GCA lesion may result in tooth‐root exposure. In such cases, a combined regenerative treatment approach may be used to achieve resolution.
Comparative Analysis of Peri‐Implant Marginal Bone Loss Based on Microthread Location: A 1‐Year Prospective Study After Loading
Authors: Song Dong‐Wook , Lee Dong‐Won , Kim Chong‐Kwan , Park Kwang‐Ho , Moon Ik‐Sang 
Published: December 2009

Background: The purpose of the present study was to investigate the short‐term effects of microthread location on peri‐implant marginal bone levels.Methods: Two types of implants, one with microthreads placed at the implant top (group A) and the other with microthreads placed 0.5 mm below the implant top (group B), were placed adjacent to each other in the partially edentulous areas of 20 patients. In total, 40 implants were placed. Bone loss around each implant was analyzed after 1 year of functional loading, and gingival parameters (modified plaque index and modified sulcus bleeding index) of the peri‐implant soft tissue were evaluated. Bone losses after loading and gingival parameters were compared using the paired t test.Results: The average bone loss was 0.16 (SD: 0.19) mm in group A and 0.30 (SD: 0.22) mm in group B after 1‐year of functional loading. The paired t test revealed a significant difference in crestal bone loss between groups A and B in individual patients (P = 0.004). No significant differences were found between the two groups for the gingival parameters.Conclusions: Less peri‐implant bone loss was observed around implants with microthreads placed at the implant top (group A) compared to those in which microthreads were placed below the top (group B). These results indicated that the microthreads acted to stabilize the peri‐implant marginal bone, and their locations played an important role in the stabilization process.
Replication of association between polymorphisms of the pancreatic ATP-sensitive potassium channel and susceptibility to type 2 diabetes in two Russian urban populations
Authors: Chistiakov Dimitry , Potapov Viktor , Khodirev Dmitry , Shamkhalova Minara , Shestakova Marina , Nosikov Valery 
Published: December 2009

AbstractThe KCNJ11 and ABCC8 genes encode components of the pancreatic ATP-sensitive potassium (KATP) channel. Previously, we reported association of the KCNJ11 E23K and ABCC8 R1273R G/A variants with type 2 diabetes (T2D) in a small Russian population sample (n=244). Here we replicated association between these genetic variants and T2D in a larger cohort (588 diabetic and 597 non-diabetic subjects). Using the ANCOVA analysis, Odds Ratios (ORs) and relationships between the carriage of a genotype and biochemical parameters of the patients were assessed and then adjusted for confounders (age, gender, HbA1c, hypertension, and obesity). The KCNJ11 K23 variant and the ABCC8 R1273R allele A showed association with higher risk of T2D (adjusted OR of 1.41 and 2.03, P<0.0001, respectively). Diabetic patients homozygous for K/K had lower 2h insulin (Padjusted=0.044). The ABCC8 A/A variant was associated with increased 2h serum insulin in diabetic and non-diabetic subjects (Padjusted=0.027 and 0.033, respectively). The carriage of the risk variant K/K of KCNJ11 E23K or A/A of ABCC8 G/A R1273R was associated with reduced response to nonsulfonylurea and sulfonylurea blockers of the pancreatic KATP channel. Adjusted attributable population risk was 3.0% (KCNJ11 E23K) and 4.8% (ABCC8 G/A) suggesting for the modest effects of these genetic variants on diabetes susceptibility.
Analysis of mtDNA A3243G mutation frequency in Hungary
Authors: Gal Aniko , Komlosi Katalin , Maasz Anita , Pentelenyi Klara , Remenyi Viktoria , Ovary Csaba , Valikovics Attila , Dioszeghy Peter , Bereczki Daniel , Melegh Bela , Molnár Maria 
Published: December 2009

Abstract
The A3243G mutation in the mitochondrial tRNALeu (UUR) gene is one of the most common causes of mitochondrial DNA related disorders. Originally it was described in MELAS syndrome (Mitochondrial Encephalomyopathy, Lactic acidosis, Stroke-like episodes), later it had been found to be associated with various phenotypes. In our study the mutation frequency of the A3243G mtDNA mutation was investigated in patients with maternal sensoneural hearing loss, stroke-like episodes, ataxia and myopathy with undetermined etiology. We screened 631 Hungarian patients in North-East, South-West and Central Hungary between 1999 and 2008 for this mutation. The mtDNA analysis was performed from blood and/or muscle tissue. The A3243G substitution was present in 6 patients in heteroplasmic form. The segregation analysis detected 8 further cases. The frequency of the A3243G mutation was 2.22% in the investigated patients. The A3243G mutation frequency in Hungary does not differ significantly from other countries using similar patient selection criteria, however in Finland a higher mutation rate was found. In studies investigated the mutation frequency of this mutation in diabetes mellitus similarly wide variety was detected as well. We conclude that the study design has a huge impact on the result of the genetic epidemiological investigation analyzing the mutation frequency of the A3243G mutation due to the broad clinical phenotype and the different mutation load in different tissues.
UARS presenting with the symptoms of anxiety and depression
Authors: Kunter Erdogan , Yetkin Ozkan , Gunen Hakan 
Published: December 2009

Abstract
Upper airway resistance syndrome (UARS) is a condition where the apnea-hypopnea index is less than 5 and respiratory-effort related arousal index is more than 10. The clinical presentation of UARS may be the same as obstructive sleep apnea-hypopnea syndrome (OSAS); it sometimes shows up with symptoms hardly suggestive of a sleep-disordered breathing. A 17 year-old male patient had applied to a local psychiatry clinic and complained of chronic fatigue, insomnia, behavioral and academic problems and was treated for anxiety and depression. After a period of unresponsive treatment, he was sent to a sleep center for evaluation of insomnia, which turned out to be a fragmented, unrefreshing sleep episode. Polysomnographical evaluation revealed that he had UARS without OSAS. His complaints decreased dramatically after he received CPAP treatment. This case shows that UARS should be considered in young patients with functional somatic syndromes even if the clinical presentation does not apparently imply the condition.
Advanced morphology and behaviour of extinct earwig-like cockroaches (Blattida: Fuziidae fam. nov.)
Authors: Vršanský Peter , Liang Jun-Hui , Ren Dong 
Published: December 2009

Advanced morphology and behaviour of extinct earwig-like cockroaches (Blattida: Fuziidae fam. nov.)We describe the extinct cockroach family Fuziidae fam. nov., represented byFuzia dadaogen. et sp. nov. from the ?Bathonian (168 Ma) Middle Jurassic sediments of Daohugou, Inner Mongolia, China. Males are characterized by unique, long and narrow bodies with a notch on forceps of earwig-like cerci, which attaches to the long external ovipositor during courtship. In a combination with the presence of male tergal glands, it appears the most advanced form of reproduction in the nearly 300 Myr history of long external ovipositor-bearing cockroaches. Its advanced morphology significantly supports attribution of living and fossil cockroaches within a single order Blattida.
North Field Well Delivery - Commitment to Top Quartile Performance
Authors: May Andrew Neal , Quaden Roy Martinus , Byrne Sean 
Published: December 2009

Abstract
This paper presents the well construction results to date of an offshore development drilling campaign, which has delivered record-breaking top-quartile performance throughout every phase of well delivery.
The primary purpose of the paper is to distribute both the techniques and lessons learnt in the Pearl well construction campaign, in order that this information can be built upon and lead to further improvements in well delivery. This is a goal that is equally important to both national governments and IOC's in the current economic climate. Some techniques are specific to carbonate reservoirs but others are valid for any offshore development where wells are pre-drilled in order to meet plateau rate from first gas.
Historically, the development wells in Qatar's giant North Field have taken in the region of 75 days to drill, complete, perforate, stimulate and clean up in preparation for their long-term production. The Pearl Well Engineering team has set a new benchmark for North Field wells, dramatically reducing this time by 40% to an average of 45 days. Every aspect of the well design and construction was examined, challenged, and where possible, optimized. Both small incremental improvements and a step-change innovation contributed to the dramatic reduction in delivery time. The paper presents full details on the incremental improvements, some of which include: cost effective Bottom Hole Assembly (BHA) selection, cement design, driving of conductors with deviated drive shoes and simple, fast and very effective stimulation design.
Focus is also given to a truly innovative approach to perforation, stimulation and clean-up. For the Shell Pearl project, these activities were carried out concurrently with the drilling of new wells. The drilling continued from the rig but at the same time the perforation, stimulation and clean-up of pre-drilled wells was conducted from specially built temporary decks installed on the permanent jacket. Therefore, the 20 days per well required to perform these operations were taken off the critical path giving a corresponding direct saving on rig days.
In conclusion, this paper describes in a section-by-section manner both the main factors that contributed to a top-quartile, 40% reduction in well delivery time, and the possible future opportunities to reduce this time still further based on the experience to date.
+1730 G/A polymorphism of the estrogen receptor β gene (ERβ) may be an important genetic factor predisposing to endometriosis
Authors: BIANCO BIANCA , CHRISTOFOLINI DENISE MARIA , MAFRA FERNANDA ABANI , BRANDES ARIEL , ZULLI KARINA , BARBOSA CAIO PARENTE 
Published: December 2009

AbstractObjective. To determine the frequency of the estrogen receptor gene (ERβ) +1730 G/A polymorphism in Brazilian women with endometriosis. Design. Case‐control study. Setting. Endometriosis Outpatient Clinic and Family Planning Outpatient Clinic of ABC Faculty of Medicine. Population. A total of 108 patients with endometriosis and a control group consisting of 210 fertile women. Methods. The ERβ gene +1730 G/A polymorphism was identified by restriction fragment length polymorphism‐polymerase chain reaction. Main outcome measure(s). Genotype distribution and allele frequency of the +1730 G/A polymorphism in the ERβ gene. Results. Genotypes GG, GA and AA of the ERβ gene presented frequencies of 50.9%, 47.2% and 1.9%, respectively, in the women with endometriosis. Among the patients with stage I/II endometriosis, 47% presented the normal homozygous genotype GG; 51% had a GA heterozygous genotype and 2% had a homozygous mutated genotype AA. Among the patients with stage III/IV endometriosis, genotypes GG, GA and AA were present in 54.3%, 44% and 1.7%, respectively. In the control group, 74.3% presented the normal homozygous genotype GG, 24.3% the heterozygous genotype GA and 1.4% the homozygous mutated genotype AA. Conclusion. The data suggest that the ERβ gene +1730 G/A polymorphism can be associated with the risk of endometriosis development, regardless of the stage of the disease.
Facility‐based audit of maternal mortality in Lebanon: A feasibility study
Authors: OSMAN HIBAH , CAMPBELL OONA MR , SINNO DIMA , ZARWI RANA , NASSAR ANWAR H 
Published: December 2009

AbstractObjective. To assess the feasibility of establishing a maternal mortality audit in Lebanon. Design. A facility‐based reproductive age mortality study (RAMOS). Methods. Records of reproductive‐age female deaths over an eight‐year period in three hospitals in Beirut, Lebanon, were reviewed. Main outcome measures. Quality of data sources, comprehensiveness of medical charts and accessibility of information. Results. Review of records was feasible. Cross‐checking three data sources identified missed cases and coding and data entry errors. The quality and accessibility of data varied between hospitals. The maternal mortality rate was 39/100,000 live births and there were 55 pregnancy‐related deaths/100,000 live births. Lack of antenatal care, delay in seeking care and over‐intervention on the part of the medical team were among problems identified. Conclusions. A facility‐based approach is a potential tool for conducting a national maternal mortality audit in a developing country like Lebanon. Computerized medical records and mandatory participation of hospitals are prerequisites for success. This would require the government to develop a cohesive national policy on reducing maternal mortality.
Predictive value of early serum β‐hCG levels after single blastocyst transfer
Authors: OCHSENKÜHN ROBERT , ARZBERGER ANDREA , VON SCHÖNFELDT VIKTORIA , ENGEL JUTTA , THALER CHRISTIAN J , NOSS ULRICH 
Published: December 2009

AbstractObjective. Analysis of serum β‐human chorionic gonadotropin (β‐hCG) levels on standardized days after oocyte retrieval (OR) following single blastocyst transfer to predict pregnancy outcome after assisted reproductive technology. Design. Retrospective study. Setting. Private fertility center. Population. A total of 230 women with an intact intrauterine pregnancy 21 days after OR and a vital term delivery (n = 191) or a miscarriage (< 10+0 gestational weeks) (n = 39) in the course of the pregnancy following single blastocyst transfer between 1999 and 2008. Methods. Blood was sampled 11, 14 and partly 21 days after OR. The serum concentration of total β‐hCG was measured by an automated quantitative immunoassay. Receiver operating characteristic curves were generated to calculate sensitivity and specificity. Main outcome measures. A total of 509 β‐hCG measurements. Results. The mean β‐hCG concentrations on days 11, 14 and 21 after OR were significantly lower in the group of patients with a miscarriage compared to the group with a term delivery (p = 0.02, < 0.001 and < 0.001 respectively). With the cut‐off values of 15 mIU/mL, 80 mIU/mL and 1500 mIU/mL on days 11, 14 and 21, the positive predictive value was 89%, 93% and 92%. The negative predictive value was 28%, 40% and 54%. Conclusions. The predictive value of a single β‐hCG measurement for pregnancy outcome after single blastocyst transfer increases between days 11 and 21 after OR. A single β‐hCG measurement on day 14 may balance the accuracy of prediction and the necessity of an early reassuring test.
Cost‐effectiveness of human papilloma virus vaccination in Iceland
Authors: ODDSSON KRISTJAN , JOHANNSSON JAKOB , ASGEIRSDOTTIR TINNA LAUFEY , GUDNASON THOROLFUR 
Published: December 2009

AbstractObjective. To evaluate the likely cost‐effectiveness of introducing routine HPV vaccination in Iceland. Design. Prospective cost‐effectiveness analysis of human papilloma virus (HPV) vaccination. Setting and sample. Population of 12‐year‐old girls in the Icelandic population. Methods. A model was developed, comparing a cohort of all 12‐year‐old girls alive in year 2006, with or without vaccination. The model was based on the epidemiology of cervical cancer in Iceland and its premalignant stages as well as the costs involved in the treatment of each stage, assuming that the vaccines only prevent infections caused by HPV 16/18 at an efficacy of 95% and participation rate of 90%, no catch‐up vaccination, no vaccination of boys and no booster dose needed. All costs were calculated on the basis of the price level of mid‐year 2006 with a 3% discount rate. Incremental cost‐effectiveness ratio calculations were performed and sensitivity analysis was carried out on factors most relevant for cost‐effectiveness. Results. Vaccination costs in excess of savings would be about €313.000/year. Vaccination would reduce the number of women diagnosed with cervical cancer by almost 9, prevent the death of 1.7 women and result in 16.9 quality‐adjusted life years gained annually. The incremental cost‐effectiveness ratio was calculated to be about €18.500/quality‐adjusted life year saved. Conclusion. HPV vaccination seems to be cost‐effective in Iceland, but this was sensitive to various parameters in the model, mainly the discount rate, the price of the vaccines and the need for a booster dose.
Wetland Link International – A Global Network for Wetland Educators
Authors: Rostron Chris 
Published: December 2009

Wetland Link International (WLI) was set up in 1991, in order to strengthen wetland education networks through wetland education centres, and has a Memorandum of Co-operation with Ramsar to deliver CEPA support internationally. The definition of a ‘wetland education centre' is broad, encompassing large built centres with interactive exhibits and thousands of visitors, to small community-run projects with little infrastructure. Anywhere that people are working to deliver messages about wetland conservation could be included. The network now has 350 members across the globe, and works with regional networks including WLI Asia and NorBalWet.DOI: 10.3126/jowe.v2i1.1856Journal of Wetlands Ecology, (2009) Vol.2, pp.46
Water Quality Status of Some Urban Ponds of Lucknow, Uttar Pradesh
Authors: Bhat Mohd Muzamil , Yazdani Taiyyaba , Narain Kamini , Yunus Mohammad , Shukla Ravinder Nath 
Published: December 2009

This study aims to investigate the physico-chemical properties of some urban ponds in the ecological system of Lucknow which is called as the city of Nawabs in U.P. But owing to the unplanned development and urbanization, the ponds of this city are struggling for their existence. Inspite of the global alarm for restoration of the water bodies, the ponds in the city are facing neglectance. For the study period ten ponds were selected. The physico-chemical parameters of the water sampled in June 2008 from ten ponds such as PH ranged from 6.55 to 7.93; Turbidity, 6.06 NTU to 8.59 NTU; Conductivity, 12.32 ms/cm to 16.84 ms/cm; D.O., 3.72 mg/l to 6.81 mg/l; B.O.D., 3.77 mg/l to 6.40 mg/l. Residual chlorine was detected only in pond A (1.09 mg/l), pond C (1.13 mg/l), pond E (1.04 mg/l) and in pond F (1.03 mg/l). Free CO2 was found between 8.7 mg/l to 19.68 mg/l. TS, TDS, and Chlorides were found much beyond the permissible levels. Alkalinity ranges between 202.55 mg/l to 310.05 mg/l; Acidity between 10.75 mg/l to 15.48 mg/l; Total Hardness between 244.49 mg/l to 254.78 mg/l. Prominent sources of pollution are the domestic sewage, kitchen flow and street runoff etc. In addition, solid waste and garbage tied in polythene bags are recorded along the banks and also floating on the water surface. Key words: Lucknow; physico-chemical; restoration; sewage; Urban pondsDOI: 10.3126/jowe.v2i1.1866 Journal of Wetlands Ecology, (2009) vol. 2, pp 67-73
Size difference effects on the bulk, and surface properties of Bi–Zn, Cu–Pb, K–Pb and K–Tl liquid alloys
Authors: Awe O. E. 
Published: December 2009

Abstract
The Flory's approximate model, and the model of Prasad et al. have been used respectively to study size effects on the bulk and surface properties of Bi–Zn, Cu–Pb, K–Pb and K–Tl liquid alloys.
Our results reveal that for the same value of order energy, W/T: the effect of size on the bulk properties is to reduce the tendencies toward phase separation in Bi–Zn and Cu–Pb while in K–Pb and K–Tl is to decrease the tendencies toward chemical ordering; size effect increases both the surface concentration and the surface tension of Bi–Zn and Cu–Pb while it decreases these same quantities in K–Pb and K–Tl.
A mesoscopic grain boundary sliding controlled flow model for superplasticity in intermetallics
Authors: Anantha Padmanabhan Kuppuswamy , Ishaq Raviathul Basariya Mohammed 
Published: December 2009

Abstract
A model based on grain/interphase boundary sliding controlled flow that develops to a mesoscopic scale (defined to be equal to or more than a grain diameter) has been used to understand superplasticity in micrometer- and sub-micrometer grained intermetallics. The procedure for analyzing the experimental stress–strain rate data at a fixed initial grain size and temperature is so developed that the free energy of activation for the rate controlling deformation process, and the long range threshold stress which has to be overcome for boundary sliding to develop to a mesoscopic scale, σ0disloc, are estimated directly from the experimental results. The analysis is validated using experimental data pertaining to a number of systems. Directions for further development of the model are indicated.
Transformation of reverted austenite in a maraging steel under external loading: an in-situ X-ray diffraction study using high-energy synchrotron radiation
Authors: Zickler Gerald A. , Schnitzer Ronald , Hochfellner Rainer , Lippmann Thomas , Zinner Silvia , Leitner Harald 
Published: December 2009

Abstract
Reverted austenite strongly influences the mechanical properties of maraging steels. Therefore, X-ray diffraction using high-energy synchrotron radiation was applied for in-situ studying of the reverse martensitic phase transformation under external load in a PH 13-8 Mo maraging steel. The volume fraction of austenite, the domain size of the crystallites, and the lattice parameters were determined as function of strain for differently aged samples. It is shown that the reverted austenite is not mechanically stable under external load. Scanning of the fractured sample along the axial direction shows that the volume fraction of the austenite and the domain sizes strongly depend on the distance from the point of fracture initiation.