bluuebunny/crossref_metadata_2025_split huggingface dataset:
Internet Resources in Medical Genetics
Authors: Waggoner Darrel J. , Pagon Roberta A. 
Published: July 2009

AbstractThis unit presents an overview of the most commonly used Web‐based information resources for clinicians seeking to apply molecular or array‐based genetic testing to patient care, obtain information on metabolic disease testing, learn more about newborn screening, or understand the molecular basis of inherited diseases, as well as for consumers seeking advocacy or scientific/management information, and also for genetics professional societies. Curr. Protoc. Hum. Genet. 62:9.12.1‐9.12.8. © 2009 by John Wiley & Sons, Inc.
Bone Marrow Engraftment Studies
Authors: Vnencak‐Jones Cindy L. 
Published: July 2009

AbstractBone marrow engraftment studies are used to evaluate the level of donor versus recipient cells in post‐transplant peripheral blood or bone marrow specimens. Unique DNA fingerprints identified from the recipient and the donor are used to determine the proportion of each contained within the total DNA extracted from the post‐transplant specimen. These percentages correspond to relative amounts of donor and recipient cells in the specimen. Engraftment studies are sequentially performed on transplant patients to monitor closely the levels of donor and recipient cells so that appropriate therapeutic intervention can proceed if and when needed. This unit describes the use of fluorescent PCR for amplification of genomic short tandem repeats (STR). STR analysis is now considered the gold standard for engraftment studies and provides a quick and accurate assessment of the contribution of both donor and/or recipient hematopoietic cells in post‐transplantation specimens. Curr. Protoc. Hum. Genet. 62:9.17.1‐9.17.34. © 2009 by John Wiley & Sons, Inc.
Improved Protocols for the Illumina Genome Analyzer Sequencing System
Authors: Quail Michael A. , Swerdlow Harold , Turner Daniel J. 
Published: July 2009

AbstractIn this unit, we describe a set of improvements we have made to the standard Illumina Genome Analyzer protocols to make the sequencing process more reliable in a high‐throughput environment, reduce amplification bias, narrow the distribution of insert sizes, and reliably obtain high yields of data. Curr. Protoc. Hum. Genet. 62:18.2.1‐18.2.27. © 2009 by John Wiley & Sons, Inc.
Analysis of Oxidative Damage by Gene‐Specific Quantitative PCR
Authors: Kovalenko Olga A. , Santos Janine H. 
Published: July 2009

AbstractThis unit describes the gene‐specific quantitative PCR‐based (QPCR) assay, which is used to measure DNA integrity of both nuclear and mitochondrial genomes based on amplification of long DNA targets. QPCR can be used to quantify the formation of DNA damage and the kinetics of DNA repair by following restoration of amplification of the target DNA over time after removal of the damaging agent. A detailed protocol to set up QPCR in any laboratory, highlighting critical parameters for successful establishment of the assay and interpretation of the results, is provided here. Advantages (e.g., the use of nanogram amounts of DNA) and limitations (e.g., the inability to define the specific type of lesion present on the DNA) of using QPCR to assay DNA damage in human cells are also described. Curr. Protoc. Hum. Genet. 62:19.1.1‐19.1.13. © 2009 by John Wiley & Sons, Inc.
A new fast Newton‐type adaptive filtering algorithm for stereophonic acoustic echo cancellation (SAEC)
Authors: Djendi Mohamed , Guessoum Abderrezak 
Published: July 2009

AbstractThis paper addresses the problem of acoustic echo cancellation. We propose a new version of the fast Newton transversal filter algorithm for stereophonic acoustic echo cancellation applications. This algorithm can be viewed as an efficient implementation of the extended two‐channel fast transversal filter algorithm. Moreover, it fits naturally within the frame of the fast version of the recursive least‐squares (RLS) algorithm, applied to the two‐channel case. To stabilize the proposed two‐channel algorithm, we have adapted and then applied a new numerical stabilization technique that has been proposed recently. The computational complexity of the proposed two‐channel algorithm is less than half the complexity of the fastest two‐channel RLS versions and very close to that of the two‐channel normalized least mean squares algorithm when its predicting part length is chosen to be small. Simulation results and comparisons in term of complexities, convergence speed and tracking with the two‐channel algorithms are presented. Copyright © 2009 John Wiley & Sons, Ltd.
Regioselective Palladium(0)‐Catalyzed Cross‐Coupling Reactions and Metal‐Halide Exchange Reactions of Tetrabromothiophene: Optimization, Scope and Limitations
Authors: Tùng Đǎng Thanh , Tuân Đǎng Thanh , Rasool Nasir , Villinger Alexander , Reinke Helmut , Fischer Christine , Langer Peter 
Published: July 2009

AbstractThe Suzuki reaction of tetrabromothiophene with arylboronic acids provides a regioselective approach to various 5‐aryl‐2,3,4‐tribromothiophenes, symmetrical 2,5‐diaryl‐3,4‐dibromothiophenes, and tetraarylthiophenes. Unsymmetrical 2,5‐diaryl‐3,4‐dibromothiophenes are prepared by Suzuki reaction of 5‐aryl‐2,3,4‐tribromothiophenes. Tetraarylthiophenes containing two different types of aryl groups are obtained by Suzuki reactions of 2,5‐diaryl‐3,4‐dibromothiophenes. During the optimization of the conditions of each individual reaction, the solvent, the catalyst and the temperature play an important role. In several cases, classical conditions [use of tetrakis(triphenylphosphane)palladium(0), Pd(PPh3)4, as the catalyst] gave excellent yields. The yields of those transformations which failed or proceeded sluggishly could be significantly improved by application of a new biarylmonophosphine ligand developed by Buchwald and co‐workers. Regioselective metal‐halide exchange reactions of tetrabromothiophene provide a convenient approach to various 2,5‐disubstituted 3,4‐dibromothiophenes. 5‐Alkyl‐2‐trimethylsilyl‐3,4‐dibromothiophenes could be prepared in one pot by sequential addition of trimethylchlorosilane and alkyl bromides. The reaction of tetrabromothiophene with methyl chloroformate and subsequent Suzuki reactions afforded 3,4‐diaryl‐2,5‐bis(methoxycarbonyl)thiophenes.
Pricing credit derivatives under stochastic recovery in a hybrid model
Authors: Höcht Stephan , Zagst Rudi 
Published: July 2009

AbstractIn this article, a framework for the joint modelling of default and recovery risk is presented. The model accounts for typical characteristics known from empirical studies, e.g. negative correlation between recovery‐rate process and default intensity, as well as between default intensity and state of the economy, and a positive dependence of recovery rates on the economic environment. Within this framework analytically tractable pricing formulas for credit derivatives are derived. The stochastic model for the recovery process allows for the pricing of credit derivatives with payoffs that are directly linked to the recovery rate at default, e.g. recovery locks. Copyright © 2009 John Wiley & Sons, Ltd.
A cataluminescence gas sensor for ammonium sulfide based on Fe3O4–carbon nanotubes composite
Authors: Xu Shuxia , Tang Li , Bi Chen , Wang Xianxiang , Lv Yi 
Published: July 2009

AbstractIn the present work, Fe3O4–carbon nanotubes (CNTs) composite was explored as a sensing material candidate for ammonium sulfide. Intense chemiluminescence emission can be observed during the catalytic oxidation of ammonium sulfide on the surface of Fe3O4–CNTs composite. Based on this phenomenon, a selective and sensitive gas sensor for the determination of ammonium sulfide was demonstrated. Under the optimized conditions, the linear range of cataluminescence intensity vs concentration of ammonium sulfide gas was 1.4–115 µg mL−1 (R = 0.998) with a limit of detection (S/N = 3) of 0.05 µg mL−1. The relative standard deviation (n = 5) for 14.3 µg mL−1 ammonium sulfide was 1.9%. There was no response to common foreign substances, such as sulfur dioxide, toluene, aether, ethanol, acetone, hydrogen sulfide, carbon bisulfide, benzene and ammonia. The proposed sensor was successfully applied for the determination of ammonium sulfide in artificial air samples. Copyright © 2009 John Wiley & Sons, Ltd.
The effects of harassment severity and organizational behavior on damage awards in a hostile work environment sexual harassment case
Authors: Cass Stacie A. , Levett Lora M. , Kovera Margaret Bull 
Published: July 2009

AbstractCommunity members reporting for jury duty (N = 128) read a sexual harassment trial summary in which harassment severity and the organization's sexual harassment policy and response were manipulated. Jurors who read the severe harassment scenario were more likely to agree that the plaintiff had suffered and should be compensated for her suffering and that the organization should be punished than were jurors who read the mild harassment scenario. When the organization had and enforced a sexual harassment policy, jurors believed that the plaintiff had suffered little and the organization should not be punished compared with conditions in which the organization did not have an enforced sexual harassment policy. Harassment severity influenced jurors' compensatory awards, and organizational behavior influenced jurors' punitive awards. These results have implications for plaintiffs, who must decide whether to claim specific or garden‐variety damages; organizations, which could create or modify sexual harassment policy to limit damages; and trial lawyers, who could tailor arguments to maximize or minimize awards. Copyright © 2009 John Wiley & Sons, Ltd.
SmartMetals: a new method for metal identification based on fuzzy logic
Authors: Pocajt Viktor , Sevarac Zoran , Kovacevic Ana 
Published: July 2009

AbstractThis paper presents a method of searching, identifying and cross‐referencing metal alloys based on their chemical composition and/or mechanical properties, typically obtained by analysis and tests. The method uses a general pattern similar to the approach of a human expert, and relies on a classification of metals based on metallurgical expertise and fuzzy logic for identifying metals and comparing their chemical and mechanical properties. The algorithm has been tested and deployed in real applications for fast metal identification and finding of unknown equivalents, by the leading companies in the field. The same principles can also be used in other domains for similar problems, such as organic and inorganic materials identification and generic drugs comparison. Copyright © 2009 John Wiley & Sons, Ltd.
Simulation of fluid–structure interaction with the interface artificial compressibility method
Authors: Degroote Joris , Swillens Abigail , Bruggeman Peter , Haelterman Robby , Segers Patrick , Vierendeels Jan 
Published: July 2009

AbstractPartitioned fluid–structure interaction simulations of the arterial system are difficult due to the incompressibility of the fluid and the shape of the domain. The interface artificial compressibility (IAC) method mitigates the incompressibility constraint by adding a source term to the continuity equation in the fluid domain adjacent to the fluid–structure interface. This source term imitates the effect of the structure's displacement as a result of the fluid pressure and disappears when the coupling iterations have converged. The IAC method requires a small modification of the flow solver but not of the black‐box structural solver and it outperforms a partitioned quasi‐Newton coupling of the two black‐box solvers in a simulation of a carotid bifurcation. Copyright © 2009 John Wiley & Sons, Ltd.
An adaptive multi‐hop forward error correction protection scheme for video streaming over wireless mesh networks
Authors: Tsai Ming‐Fong , Shieh Ce‐Kuen , Hwang Wen‐Shyang , Deng Der‐Jiunn 
Published: July 2009

AbstractTraditional forward error correction (FEC) mechanisms can be divided into end‐to‐end FEC protection schemes and hop‐by‐hop FEC protection schemes. The end‐to‐end FEC protection schemes over‐allocate FEC redundancy to each link and may induce a self‐congestion effect in a link. The hop‐by‐hop FEC protection scheme incurs a long end‐to‐end delay that harms the video performance at the video receiver. Accordingly, the Adaptive Multi‐Hop FEC (AM‐FEC) protection scheme is proposed in this paper to improve the quality of video streaming data over Wireless Mesh Networks by means of simultaneously minimizing the end‐to‐end delay and reducing the FEC computational cost. The AM‐FEC protection scheme uses a heuristic algorithm to minimize the number of FEC‐encoded segments between the video sender and receiver. Moreover, according to the decodable frame rate the AM‐FEC protection scheme can dynamically adjust FEC redundancy on each link to outperform end‐to‐end FEC protection schemes and hop‐by‐hop FEC protection schemes. In the experiments, the AM‐FEC protection scheme achieves timely loss recovery for delay‐sensitive video streaming and outperforms traditional FEC protection schemes in terms of video peak signal‐to‐noise ratio. Copyright © 2009 John Wiley & Sons, Ltd.
Self‐confirmation strivings in depression: An extension to the affective domain using an experimental design
Authors: Rehman Uzma S. , Ebel‐Lam Anna , Mortimer Amanda , Mark Kristen 
Published: July 2009

AbstractThe purpose of the present study was to compare the emotional reactions of depressed and nondepressed individuals to experiences of romantic rejection versus acceptance. We tested our hypotheses in a sample of 28 depressed and 43 nondepressed undergraduate students. In support of self‐consistency theories, the results showed that depressed individuals reported significantly greater negative mood in the romantic acceptance versus rejection condition, while there was no significant difference across the two conditions in the self‐reported mood of nondepressed individuals. Further, symptoms of anxiety mediated the interactive effects of depression status and rejection status on mood. Our findings demonstrate how the responses of depressed individuals to interpersonal feedback contribute to their affective disturbance. Copyright © 2009 John Wiley & Sons, Ltd.
Seismic rehabilitation performance of steel side plate moment connections
Authors: Chou Chung‐Che , Tsai Keh‐Chyuan , Wang Yuang‐Yu , Jao Chih‐Kai 
Published: July 2009

AbstractMoment connections in an existing steel building located in Kaohsiung, Taiwan were rehabilitated to satisfy seismic requirements based on the 2005 AISC seismic provisions. Construction of the building was ceased in 1996 due to financial difficulties and was recommenced in 2007 with enhanced connection performance. Steel moment connections in the existing building were constructed by groove welding the beam flanges and bolting the beam web to the column. Four moment connections, two from the existing steel building, were cyclically tested. A non‐rehabilitated moment connection with bolted web‐welded flanges was tested as a benchmark. Three moment connections rehabilitated by welding full‐depth side plates between the column face and beam flange inner side were tested to validate the rehabilitation performance. Test results revealed that (1) the non‐rehabilitated existing moment connection made by in situ welding process prior to 1996 had similar deformation capacity as contemporary connection specimens made by laboratory welding process, (2) all rehabilitated moment connections exhibited excellent performance, exceeding a 4% drift without fractures of beam flange groove‐welded joints, and (3) presence of the full‐depth side plates effectively reduced beam flange tensile strain near the column face by almost half compared with the non‐rehabilitated moment connection. The connection specimens were also modeled using the non‐linear finite element computer program ABAQUS to further confirm the effectiveness of the side plate in transferring beam moments to the column and to investigate potential sources of connection failure. A design procedure was made based on experimental and analytical studies. Copyright © 2009 John Wiley & Sons, Ltd.
Seismic performance of an unreinforced masonry building: An experimental investigation
Authors: Bothara Jitendra K. , Dhakal Rajesh P. , Mander John B. 
Published: July 2009

AbstractThis paper presents the results of an experimental investigation carried out to investigate the seismic performance of a two storey brick masonry house with one room in each floor. A half‐scale building constructed using single wythe clay brick masonry laid in cement sand mortar and a conventional timber floor and timber roof clad with clay tiles was tested under earthquake ground motions on a shaking table, first in the longitudinal direction and then in the transverse direction. In each direction, the building was subjected to different ground motions with gradually increasing intensity. Dynamic properties of the system were assessed through white‐noise tests after each ground motion. The building suffered increasing levels of damage as the excitations became more severe. The damage ranged from cracking to global/local rocking of different piers and partial out‐of‐plane failure of the walls. Nevertheless, the building did not collapse under base excitations with peak ground acceleration up to 0.8g. General behaviour of the tested building model during the tests is discussed, and fragility curves are developed for unreinforced masonry buildings based on the experimental results. Copyright © 2009 John Wiley & Sons, Ltd.
A note on two upwind strategies for RBF‐based grid‐free schemes to solve steady convection–diffusion equations
Authors: Sanyasiraju Y. V. S. S. , Chandhini G. 
Published: July 2009

AbstractIn this paper, two radial basis function (RBF)‐based local grid‐free upwind schemes have been discussed for convection–diffusion equations. The schemes have been validated over some convection–diffusion problems with sharp boundary layers. It is found that one of the upwind schemes realizes the boundary layers more accurately than the rest. Comparisons with the analytical solutions demonstrate that the local RBF grid‐free upwind schemes based on the exact velocity direction are stable and produce accurate results on domains discretized even with scattered distribution of nodal points. Copyright © 2009 John Wiley & Sons, Ltd.
Brief cognitive screening instruments: an update
Authors: Ismail Zahinoor , Rajji Tarek K. , Shulman Kenneth I. 
Published: July 2009

AbstractObjectiveTo review the recent literature on cognitive screening with a focus on brief screening methods in primary care as well as geriatric services.DesignThe Medline search engine was utilized using the keyword search terms ‘cognitive screening’, ‘cognitive assessment’, and ‘dementia screening’ limiting articles to those published in English since 1998.Results679 abstracts were retrieved. Articles focusing on attitudes toward cognitive screening, current screening practices, promising new instruments and more recent updates contributing significant information on established instruments were retrieved and incorporated into this review. Reference lists were reviewed for relevant contributing articles. Instruments recommended from previous reviews of cognitive screening and those identified in surveys as most frequently used in primary care and geriatric settings were emphasized in this review.ConclusionsDementia remains under‐diagnosed in the elderly population. Despite significant limitations, the Mini Mental State Exam remains the most frequently used cognitive screening instrument. Its best value in the community and primary care appears to be for the purpose of ruling out a diagnosis of dementia. Instruments such as the Mini‐Cog, Memory Impairment Screen (MIS), and the General Practitioner Assessment of Cognition (GPCOG) have consistently been recognized for utility in primary care. The clock drawing test (CDT) and newer instruments such as the Montreal Cognitive Assessment (MoCA) and the Rowland Universal Dementia Assessment Scale (RUDAS) are gaining credibility due to improvements in sensitivity, addressing frontal/executive functioning, and decreasing susceptibility to cultural and educational biases. Copyright © 2009 John Wiley & Sons, Ltd.
Effectiveness of an individualized functional training program on affective disturbances and functional skills in mild and moderate dementia—a randomized control trial
Authors: Lam Linda CW , Lui Victor WC , Luk Daisy NY , Chau Rachel , So Clifton , Poon Vickie , Tam Peter , Ching Raymond , Lo Henry , Chiu Julian , Fung Ada , Ko Flora SL 
Published: July 2009

AbstractObjectivesWe reported the findings of a randomized controlled trial (RCT) to examine the effects of an individualized functional enhancement program (FEP) on functional skills and mood symptoms in mild and moderate dementia.Subjects & Methods74 Chinese older persons with dementia were recruited into a skills training program by occupational therapists (OT). Thirty seven subjects were trained with an individualized selection of daily activities (FEP Intervention, I); 37 were trained with general occupational therapy (Control, C). The FEP comprised of twice weekly group sessions of skills training and problem solving using cognitive behavioral approach.ResultsAt 1 month after completion of program, both I and C subjects showed an improvement in process skills of the assessment of motor and process skills (AMPS)(paired t‐tests, p < 0.05). At 4 months post‐program, the I group showed a further reduction of cornell scale for depression in dementia (CSDD) scores (paired t‐test, p = 0.02); Apathy improved at 1 month post‐training (p = 0.04), but deteriorated at 4 months (p = 0.01). Group differences in changes of mood and functional scores were not significant (ANVOCA, p > 0.05).ConclusionsThe findings suggested a potential benefit for individualized occupational therapy. It should be tailor made with individual needs and continued for sustained effectiveness. Copyright © 2009 John Wiley & Sons, Ltd.
Support/services among family caregivers of persons with dementia—perceived importance and services received
Authors: Alwin Jenny , Öberg Birgitta , Krevers Barbro 
Published: July 2009

AbstractObjectiveThe aim of this study was to examine what family caregivers of persons with dementia perceive as important types of support/services in relation to experienced negative impact (NI) due to the caregiver situation, and to investigate if caregivers receive the support/services perceived as important.MethodThe study was based on the Swedish part of the EUROFAMCARE project and included 110 caregivers of persons with dementia. Data were collected primarily through structured telephone interviews. The caregivers were divided into two groups, a higher NI group and a lower NI group, based on the NI scale from the COPE index.ResultsGetting information and having someone to talk to were perceived as very important types of support/services by the highest proportion of caregivers in both groups. Data indicated only one significant difference; a higher proportion of caregivers in the higher NI group reported being able to participate in activities outside of caring as very important. There was also an indication that a higher proportion of caregivers in the lower NI group perceived information about the disease as very important. Support/services perceived as important by the caregivers were received both to a high and a low degree.ConclusionThe results from this study suggest that there is almost no difference between groups of caregivers experiencing higher and lower NI regarding their perception of what are important types of support/services. The caregivers rated different types of support/services within the areas of information, relief and counselling as very important. Copyright © 2009 John Wiley & Sons, Ltd.