bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'Écriture ou la vie, une écriture résiliente
Authors: Benestroff Corinne 
Published: October 2010

Résumé En racontant bien après les faits sa déportation à Buchenwald Jorge Semprun donne à son écriture même les traits de la résilience : si cette dernière se fonde psychologiquement sur la résistance au traumatisme, la préservation du moi, et la lutte contre la dépression, le tout enraciné dans le travail du deuil, elle se traduit par l’humour, l’importance de la culture, l’inter- et l’intratextualité, ou les oxymores, en contrepoint des brutales interventions des traumatismes.
Autour du livre Histoire de l'autre
Authors: Mégevand Martin 
Published: October 2010

Résumé	Deux équipes d’historiens venus de part et d’autre du conflit israélopalestinien furent chargées en 2002 de produire une histoire de la déclaration de Balfour, de la guerre de 1948 et de l’Intifada de 1987. Le livre qui en résulta présentait sur chaque page trois colonnes, à droite et à gauche les textes des historiens, et au centre une colonne pour annoter. Refusé par les instances éducatives des deux nations, le livre a trouvé son lectorat en arabe et hébreu, et été traduit en italien, allemande et français. La version française préfacée par Vidal-Naquet oppose fortement les deux textes autour d’une ligne verticale qui a éliminé la colonne centrale, et fit l’objet d’une conférence multidisciplinaire en 2006. Une présentation du livre par Martin Mégevand est suivie de trois contributions, celles de Jean-Pierre Klein (psychiatre), de Michel Costantini (sémioticien) et de Pierre Pachet (écrivain).
L'imaginaire unificateur ? À propos du livre Histoire de l'autre
Authors: Klein Jean-Pierre 
Published: October 2010

Résumé La lecture d’ Histoire de l’autre présente l’expérience déprimante de deux narrations irréconciliables dont chacune tient du mythe identitaire ; mais c’est précisément leur aspect fantasmatique qui ouvre à la possibilité de mettre les imaginaires qui les soutiennent au travail dans le but de se tourner vers l’avenir.
« Histoires de soi, récits pour l'autre »
Authors: Costantini Michel 
Published: October 2010

Résumé L’histoire est un passage d’un « Je-vrai » à un « Il-vrai » au travers d’un « On-vrai », où la question de qui se tient derrière ce « on » et de sa capacité à assumer un « nous » détermine le passage au « Il-vrai » – avec le risque qu’un « Je-vrai » peut se déguiser en « Il-vrai » en restreignant l’accès au « On », et en tout cas peut toujours être lu ainsi. La lecture d’ Histoire de l’autre au moyen du filtre de l’histoire et de la pensée politique grecques permet de le voir comme une étape dans la construction d’un « nous » rassemblant ce qui ne sont pour le moment que deux « on »...
PHENYTOIN-ASSOCIATED LYMPHOADENOPATHY MIMICKING A PERIPHERAL T-CELL LYMPHOMA
Authors: Johns Mark E. , Moscinski Lynn C. , Sokol Lubomir 
Published: October 2010

We report a case of phenytoin-induced pseudolymphoma in a 28-year-old male with a history of autism and seizure disorder. The patient presented with bilateral cervical lymphadenopathy that was shown to be moderately to markedly FDG-avid on a whole body PET/CT scan. Flow cytometry analysis of peripheral blood and bone marrow mononuclear cells detected identical T cell population with aberrant immunophenotype. Additionally, a TCR beta gene was found to be clonally rearranged in both peripheral blood and bone marrow supporting a clonal origin of atypical T cells. However, no such clonal population of T-cells could be detected in a pathologic specimen obtained from an excisional biopsy of one of the patient’s cervical lymph nodes. After discontinuing the patient’s phenytoin, his lymphadenopathy has nearly completely resolved and circulation clonal T cell population disappeared with 12 months of follow-up.
The spectrum of coincident entities with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) diagnosed by cytology
Authors: Kastenbaum Hannah A. , Khalbuss Walid E. , Felgar Raymond E. , Stoller Ronald , Monaco Sara E. 
Published: October 2010

Background:
The cytologic diagnosis of Small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) often relies on finding a small lymphoid population with the characteristic immunoprofile by ancillary testing. There are only a few reports of other processes identified with SLL/CLL. The aim of this study was to review the fine needle aspiration (FNA) and touch prep (TP) diagnoses of SLL/CLL in order to identify any coincident entities.

Materials and Methods:
We retrospectively reviewed all FNA and TP cytology cases between January 2005 and May 2009 with a diagnosis of SLL/CLL to determine the presence of any coincident process.

Results:
We identified 29 cases, including 23 FNAs and six TPs, from 23 patients. Ancillary studies were utilized in 97% of the cases, including flow cytometry (FC, 79%), immunohistochemistry (IHC, 55%), fluorescent in situ hybridization studies (24%) and special stains (7%). Coincident entities were identified in nine cases (31%) and included seven (28%) neoplastic entities (Hodgkin lymphoma [HL], adenocarcinoma, squamous cell carcinoma, seminoma) and two (7%) non-neoplastic entities (infection and immunoglobulin containing cells). Six cases (21%) suspicious for large cell transformation were also identified.

Conclusion:
In our review of SLL/CLL, coincident entities were present in 31% of the cases and included a spectrum of non-neoplastic and neoplastic processes. FC was the most frequently utilized ancillary test, but IHC provided important information by excluding a mantle cell lymphoma or confirming a coincident process. Thus, cytomorphologic evaluation in these patients is important due to the high risk of a coincident process that may not be apparent by FC alone and may require clinical management.
A Method for Preparing Primary Retinal Cell Cultures for Evaluating the Neuroprotective and Neuritogenic Effect of Factors on Axotomized Mature CNS Neurons
Authors: Grozdanov Veselin , Müller Adrienne , Sengottuvel Vetrivel , Leibinger Marco , Fischer Dietmar 
Published: October 2010

AbstractRetinal ganglion cells (RGCs) are central nervous system neurons with a very limited ability for axon regeneration. This unit details a cell culture technique, which can be used to functionally screen factors/compounds for their neuritogenic and neuroprotective effects on RGCs. In this protocol, the retina is isolated, digested in a papain solution, and after trituration, the RGCs are cultured. The neuritogenic effect of applied factors/compounds on RGCs in the medium is functionally determined by measuring the average neurite length of βIII‐tubulin‐positive RGCs in culture after 3 days. This protocol takes 3 to 7 days to perform depending on the application to complete, and is suitable to reliably test pharmacological and genetic approaches for their axon growth‐promoting and neuroprotective potential on mature RGCs. Curr. Protoc. Neurosci. 53:3.22.1‐3.22.10. © 2010 by John Wiley & Sons, Inc.
Social Recognition Assay in the Rat
Authors: Mathiasen Joanne R. , DiCamillo Amy 
Published: October 2010

AbstractNeuropsychiatric disorders encompass a broad patient population in a variety of disease states across all age groups and are often accompanied by deficits in short‐term/working memory. However, most preclinical models that allow for an assessment of cognitive enhancement do not provide robust behavioral readouts with a level of throughput sufficient to support modern drug discovery efforts. The rat social recognition assay presented in this unit is one exception that has been increasingly employed to test new chemical entities for enhancing cognitive activity. The test is simple in design and takes advantage of the spontaneous behavior of rats to investigate conspecifics. The protocol in this unit is designed to evaluate the effects of a test substance on the short‐term/working memory of adult male rats employing 30‐min or 2‐hr pretreatment times. Curr. Protoc. Neurosci. 53:8.51.1‐8.51.15. © 2010 by John Wiley & Sons, Inc.
Modeling Appetitive Pavlovian‐Instrumental Interactions in Mice
Authors: O'Connor Eoin C. , Stephens David N. , Crombag Hans S. 
Published: October 2010

AbstractIn appetitive Pavlovian associative learning, a stimulus (conditioned stimulus, CS) that has been associated with the delivery of a reinforcing event (unconditioned stimulus, US; e.g., food) can subsequently elicit or modulate goal‐directed instrumental behaviors. For example, a Pavlovian CS can serve to reinforce (novel) instrumental behavior (conditioned reinforcement or CRf), or it can energize and potentiate ongoing instrumental responses when presented non‐contingently (Pavlovian‐instrumental transfer or PIT). Notably, these different effects of a Pavlovian CS on instrumental behavior are mediated by dissociable psychological and neurobiological mechanisms. Given the critical role that Pavlovian‐instrumental interactions play in regulating motivated behavior and maladaptive manifestations of motivation such as eating disorders and addictions, understanding the underlying psychological and neurobiological mechanisms will be important. This unit describes behavioral protocols that produce robust and reliable PIT and CRf in mice and that open the door for future studies using transgenic approaches into the molecular mechanisms underlying associative learning and motivation.Curr. Protoc. Neurosci. 53:8.25.1‐8.25.27. © 2010 by John Wiley & Sons, Inc.
Drug‐Induced Sexual Dysfunction in Rats
Authors: Chan Johnny S.W. , Waldinger Marcel D. , Olivier Berend , Oosting Ronald. S. 
Published: October 2010

AbstractThis unit describes the testing of sexual behaviors of male Wistar rats. The described test enables the detection of stimulatory and inhibitory profiles of compounds. The test includes four training sessions to reach a stable sexual performance, followed by acute and/or chronic administration of drugs. The main quantifiable sexual behaviors are number of mounts (no vaginal penetration), intromissions (vaginal penetration), and ejaculations. By comparing the test compound to reference compound(s), sexual (side) effects can be determined. Curr. Protoc. Neurosci. 53:9.34.1‐9.34.11. © 2010 by John Wiley & Sons, Inc.
Evaluation and Purchase of Confocal Microscopes: Numerous Factors to Consider
Authors: Zucker Robert M. , Chua Michael 
Published: October 2010

AbstractThe purchase of a confocal microscope is a difficult decision. Many factors need to be considered, which include hardware, software, company, support, service, and price. These issues are discussed to help guide the purchasing process. Curr. Protoc. Cytom. 54:2.16.1‐2.16.12. © 2010 by John Wiley & Sons, Inc.
Titration of Fluorochrome‐Conjugated Antibodies for Labeling Cell Surface Markers on Live Cells
Authors: Hulspas Ruud 
Published: October 2010

AbstractNonspecific antibody binding is best eliminated by optimizing the amount and concentration of the antibody. An antibody titration assay should be applied to determine the antibody amount and concentration resulting in the highest signal of the positive population and the lowest signal of the negative population. While conventional antibody titration protocols focus on the concentration of the antibody, this protocol for antibody titration considers the antibody concentration, as well as the antibody amount. Thus, it is designed to find the optimal antibody concentration for labeling antigens expressed on the surface membrane of live cells, while nonspecific antibody binding is kept to a minimum. Curr. Protoc. Cytom. 54:6.29.1‐6.29.9. © 2010 by John Wiley & Sons, Inc.
Microsphere‐Based Flow Cytometry Protease Assays for Use in Protease Activity Detection and High‐Throughput Screening
Authors: Saunders Matthew J. , Edwards Bruce S. , Zhu Jingshu , Sklar Larry A. , Graves Steven W. 
Published: October 2010

AbstractThis protocol describes microsphere‐based protease assays for use in flow cytometry and high‐throughput screening. This platform measures a loss of fluorescence from the surface of a microsphere due to the cleavage of an attached fluorescent protease substrate by a suitable protease enzyme. The assay format can be adapted to any site or protein‐specific protease of interest and results can be measured in both real time and as endpoint fluorescence assays on a flow cytometer. Endpoint assays are easily adapted to microplate format for flow cytometry high‐throughput analysis and inhibitor screening. Curr. Protoc. Cytom. 54:13.12.1‐13.12.17. © 2010 by John Wiley & Sons, Inc.
Kaede‐Centrin1 Labeling of Mother and Daughter Centrosomes in Mammalian Neocortical Neural Progenitors
Authors: Imai Janice H. , Wang Xiaoqun , Shi Song‐Hai 
Published: October 2010

AbstractThe importance of the centrosome in regulating basic cellular processes and cell fate decisions has become increasingly evident from recent studies tracing the etiology of developmental disorders to mutations in genes encoding centrosomal proteins. This unit details a protocol for a fluorescence‐based pulse labeling of centrioles of neural progenitor cells in the developing neocortex of mice. In utero electroporation of Kaede‐Centrin1 followed by in utero or ex vivo photoconversion allows a direct monitoring of the inheritance of centrosomes containing centrioles of different ages in dividing neocortical neural progenitors (i.e., radial glial cells). This is achieved by combining the irreversible photoconversion capacity of the Kaede protein from green to red fluorescence with the faithful duplication of the centrosome during each cell cycle. After two mitotic divisions following photoconversion, mother centrosomes containing the original labeled centriole appear in both red and green fluorescence, and can be distinguished from daughter centrosomes which appear in green fluorescence only. This facilitates the study of the inheritance and behavior of the mother and daughter centrosomes in asymmetric cell divisions in the developing mammalian neocortex. Curr. Protoc. Stem Cell Biol. 15:5A.5.1‐5A.5.12. © 2010 by John Wiley & Sons, Inc.
High‐Throughput Assessment of Bacterial Growth Inhibition by Optical Density Measurements
Authors: Campbell Jennifer 
Published: October 2010

AbstractThe increasing incidence of antibiotic‐resistant bacterial infections both in hospitals and in the community intensifies the need for new antibacterial strategies and targets. Although high‐throughput screening against live bacteria allows rapid discovery of compounds with growth‐inhibitory activities, these efforts have failed to fill the pipeline with the anticipated antibacterial compounds because target identification is often onerous. Recently, a strategy was reported that employs a bacterial growth inhibition assay readout using optical density measurements on paired strains—both a wild‐type strain and a pathway‐null mutant—to find inhibitors of wild‐type bacterial growth that specifically target conditionally essential enzymes in the pathway of interest. Protocols are provided here for determining the robustness of an assay, screening in a high‐throughput format, and setting up dose‐response curves in paired Staphylococcus aureus strains. However, the protocols can be used to screen for growth‐inhibitory compounds in any bacterial strain of interest. Curr. Protoc. Chem. Biol. 2:195‐208 © 2010 by John Wiley & Sons, Inc.
Space use selectivity by chimpanzees and gorillas in an indoor–outdoor enclosure
Authors: Ross S.R. , Calcutt S. , Schapiro S.J. , Hau J. 
Published: October 2010

AbstractUnderstanding the relationship between physical environments and nonhuman primate behavior is a key element for effective care and management in a range of settings. The physical features of the captive environment, including not only gross useable space but also environmental complexity, can have a significant influence on primate behavior and ultimately, animal welfare. But despite this connection, there remains relatively little conclusive data on how captive primates, especially great apes, use the spaces provided to them, especially in modern, indoor–outdoor enclosures that have become more prevalent in recent years. In this study, we used four years of detailed data on where 23 great apes (chimpanzees and gorillas) positioned themselves within a modern, indoor–outdoor zoo enclosure to determine not only how the apes utilized their space but also how access to outdoor areas affected their spatial selectivity. We found that both species used relatively little of their available space: chimpanzees and gorillas spent half their time in only 3.2 and 1.5% of their useable three‐dimensional space, respectively. Chimpanzees utilized the outdoor space more than gorillas, but access to the outdoors did not affect space selectivity in the indoor area for either species. Although both species of ape were highly selective in their space use, consideration should be given to the importance of providing the choice to locate in a variety of spaces, including outdoor areas. These data represent an extremely detailed account of space selectivity by great apes in an indoor–outdoor environment and have substantial implications for future facility design and captive primate management. Am. J. Primatol. 73:197–208, 2011. © 2010 Wiley‐Liss, Inc.
Inter‐unit contests within a provisioned troop of Sichuan snub‐nosed monkeys (Rhinopithecus roxellana) in the Qinling Mountains, China
Authors: Zhao Qing , Tan Chia L. 
Published: October 2010

AbstractNumerical superiority does not always ensure victory in intergroup contests. Although group size is likely to determine the maximum resource holding potential (RHP) of a group, the realized RHP is the collective outcome of individual group members' choices about participation in any given contest. For any group member, the choice about participation should be based on the assessment of costs and benefits that are affected by both ecological and social factors. In this study, we studied inter‐unit contests in a provisioned troop of Sichuan snub‐nosed monkeys (Rhinopithecus roxellana). We spent 368 hr in contact with 9 one‐male units sharing the same home range, during which we recorded 148 inter‐unit contests at a provisioning site. Inter‐unit contests always started as inter‐individual contests. Contests escalated only when the two individuals were of different age‐sex classes and one was an adult male. When a contest escalated, additional individuals were likely to get involved, and the outcome of the contest depended on unit members' choices about participation. The superiority in the number of participants rather than the superiority in unit size led to victory in inter‐unit contests, given that the difference in unit size did not predict a difference in the number of participants. Unit members were more likely to support others in inter‐unit contests in winter when food was sparse than in spring when food was abundant. In addition, unit members were more likely to support others in escalated contests than in those resulting in displacement, indicating that they tended to alter the outcome of a contest to gain immediate benefit. Although males initiated most inter‐unit contests, a clear win–loss was most likely when females joined the fight. This sex difference may reflect the benefits to males vs. females of living in a multi‐level society. Am. J. Primatol. 73:262–269, 2011. © 2010 Wiley‐Liss, Inc.
Impact of injection‐molding processing parameters on the electrical, mechanical, and thermal properties of thermoplastic/carbon nanotube nanocomposites
Authors: Rios P. F. , Ophir A. , Kenig S. , Efrati R. , Zonder L. , Popovitz‐Biro R. 
Published: October 2010

AbstractThermoplastic nanocomposites, based on high‐density polyethylene, polyamide 6, polyamide 66, poly(butylene terephthalate), or polycarbonate and containing multiwalled carbon nanotubes (CNTs), were compounded with either neat CNTs or commercial CNT master batches and injection‐molded for the evaluation of their electrical, mechanical, and thermal properties. The nanocomposites reached a percolation threshold within CNT concentrations of 2–5 wt %; however, the mechanical properties of the host polymers were affected. For some nanocomposites, better properties were achieved with neat CNTs, whereas for others, master batches were better. Then, polycarbonate and poly(butylene terephthalate), both with a CNT concentration of 3 wt %, were injection‐molded with a screening design of experiments (DOE) to evaluate the effects of the processing parameters on the properties of the nanocomposites. Although only a 10‐run screening DOE was performed, such effects were clearly observed. The volume resistivity was significantly dependent on the working temperature and varied up to 4 orders of magnitude. Other properties were also dependent on the processing parameters, albeit in a less pronounced fashion. Transmission electron microscopy indicated that conductive samples formed a percolation network, whereas nonconductive samples did not. In conclusion, injection‐molding parameters have a significant impact on the properties of polymer/CNT nanocomposites, and these parameters should be optimized to yield the best results. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Relating scratch resistance to injection molding‐induced morphology of polypropylene
Authors: Kobayashi Yutaka , Otsuki Yasuhiko , Kanno Hiroaki , Hanamoto Yasuhiro , Kanai Toshitaka 
Published: October 2010

AbstractThe relationship between the scratch resistance and the injection molding‐induced morphology of polypropylene (PP) was investigated. The crystal structure near the surface was controlled by the mold temperature and the doping of a nucleating agent (NA). Although α‐ and β‐NA were used to improve the scratch resistance of PP that was molded at a mold temperature of 40°C, both of the NAs only slightly affected the scratch resistance due to low crystallinity at the surface. When the mold temperature was increased, the skin layer became thin and a β‐form crystal formed. Plastic deformation under the scratch was limited in the frozen layer. Consequently, the thickness of the frozen layer (which had low crystallinity) had the predominant effect on the scratch resistance in comparison to the polymorphism differences. The crystal morphology was analyzed with synchrotron micro‐beam wide angle X‐ray diffraction and Fourier transform infrared spectroscopy. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011