bluuebunny/crossref_metadata_2025_split huggingface dataset:
Finite-dimensional perturbation of the Dirichlet boundary value problem for the biharmonic equation
Authors: Berikkhanova Gulnaz 
Published: May 2024

Abstract
The biharmonic equation is one of the important equations of mathematical physics, describing the behaviour of harmonic functions in higher-dimensional spaces. The main purpose of this study was to construct a finite-dimensional perturbation for the Dirichlet boundary value problem associated with the biharmonic equation. The methodological basis for this study was an integrated approach that includes mathematical analysis, algebraic methods, operator theory, and the theorem on the existence and uniqueness of a solution for a boundary value. The main tool is a finite-dimensional perturbation, which allows for examining the properties and behaviour of boundary value problems in as much detail as possible. In the study, descriptions of correctly solvable internal boundary value problems for a biharmonic equation in non-simply connected domains were considered in detail. The study is also devoted to the search for solutions and the analytical representation of resolvents of boundary value problems for a biharmonic equation in multi-connected domains. Within the framework of the study, theorems and their consequences were proved, and a finite-dimensional perturbation was constructed for the Dirichlet boundary value problem. Analytical representations of resolvents of boundary value problems for a biharmonic equation in multi-connected domains were also obtained. The examination of a finite-dimensional perturbation of the Dirichlet boundary value problem for a biharmonic equation has expanded the understanding of the properties of this equation in various contexts.
Investigation on electrochemical corrosion behavior and mechanical properties of Fe-nano particles produced by high-energy ball milling technique
Authors: Milton Prince Herald , Elangeeran Sivasenthil , Husain Fohad Mabood , Vignesh Shanmugam , Arangarajan Viji 
Published: May 2024

Abstract
This study focuses on converting iron particles from grinding sludge, after removing impurities, into Fe-nanoparticles using high-energy ball billing. The goal is to examine the corrosion behaviors and mechanical properties of these Fe-nanoparticles. Nanostructured Fe-powder was synthesized through a process involving 10 h of high-energy ball milling, followed by conventional hot pressing and sintering. Structural and microstructural properties were thoroughly examined using techniques such as X-ray diffraction (XRD), optical microscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and elemental diffraction spectroscopy. Upon sintering, SEM and TEM analyses unveiled the formation of a nanostructured alloy within the samples. Notably, the milled sample exhibited high hardness value, measuring at 155 HV. However, it is noteworthy that the un-milled sample demonstrated superior compression strength compared to its milled counterpart. Furthermore, the corrosion behavior of the samples was evaluated through electrochemical corrosion studies. Interestingly, the sample subjected to 10 h of milling (coin number 5) displayed a significantly lower corrosion rate, measuring at 1.3921 mm/year, suggesting enhanced corrosion resistance attributed to the nano structuring process.
The Power of Linking Organ Systems
Authors: Fraley Amber D. , Kang ChulHee , Vilchiz Victor H. , Lee Cathy 
Published: May 2024

Understanding the body’s homeostasis through interactions among the eleven organ systems is an essential foundation for pre-professional undergraduate students studying human anatomy and physiology. This knowledge enables students to understand the pathophysiology of various disease states that result from non homeostatic conditions. We created an organ systems-based applied learning module containing the signs and symptoms of diabetic ketoacidosis (DKA), which can assist in increasing student engagement while making connections between normal conditions and disease states. The purpose of this module was to encourage students to use critical thinking skills and apply what they have learned in the classroom to real-world situations.
Anatomy and Physiology II students at Gordon State College first learned about four major organ systems: endocrine, cardiovascular, respiratory, and urinary. Students completed each lesson and the corresponding assignment containing the basic functions of each organ system. Students then identified the organ systems’ physiological contributions to the signs and symptoms of DKA, such as hyperglycemia, ketoacidosis, ketonuria, hypokalemia, and osmotic diuresis. At the end of the semester, the students presented posters summarizing their overall understanding of the eleven organ systems’ involvement with the signs and symptoms of DKA. This learning module with the DKA poster project offered an innovative way for students to apply their classroom learning to real-world situations relevant to their potential future careers.
Highly expressed lncRNA H19 in endometriosis promotes aerobic glycolysis and histone lactylation
Authors: Wen Xiaoyang , Zhang Jingyang , Xu Zihan , Li Muzi , Dong Xiaotong , Du Yanbo , Xu Zhen , Yan Lei 
Published: May 2024

In brief
Abnormal glucose metabolism may be involved in the pathogenesis of endometriosis. The present study identifies that highly expressed H19 leads to increased aerobic glycolysis and histone lactylation levels in endometriosis.

Abstract
Previous studies from our group and others have shown increased IncRNA H19 expression in both the eutopic endometrium and the ectopic endometriosis tissue during endometriosis. In this study, we use immunofluorescence, immunohistochemistry, and protein quantification to determine that levels of aerobic glycolysis and histone lactylation are increased in endometriosis tissues. In human endometrial stromal cells, we found that high H19 expression resulted in abnormal glucose metabolism by examining the levels of glucose, lactate, and ATP and measuring protein levels of enzymes that participate in glycolysis. At the same time, immunofluorescence and western blotting demonstrated increased histone lactylation in H19 overexpressing cells. Altering aerobic glycolysis and histone lactylation levels through the addition of sodium lactate and 2-deoxy-d-glucose demonstrated that increased aerobic glycolysis and histone lactylation levels resulted in enhanced cell proliferation and cell migration, contributing to endometriosis. To validate these findings in vivo, we constructed an endometriosis mouse model, demonstrating similar changes in endometriosis tissues in vivo. Both aerobic glycolysis and histone lactylation levels were elevated in endometriotic lesions. Taken together, these data demonstrate elevated expression levels of H19 in endometriosis patients promote abnormal glucose metabolism and elevated histone lactylation levels in vivo, enhancing cell proliferation and migration and promoting the progression of endometriosis. Our study provides a functional link between H19 expression and histone lactylation and glucose metabolism in endometriosis, providing new insights into disease mechanisms that could result in novel therapeutic approaches.
Karjeros sprendimų priėmimo sunkumų klausimyno lietuviškosios versijos psichometrinės charakteristikos studentų imtyje
Authors: Vadvilavičius Tadas , Burčikaitė Donata , Jakštaitytė Karolina , Petrulis Tadas 
Published: May 2024

Valid and reliable methods are needed to assess the difficulties young people often face in making career-related decisions. A cross-sectional study was conducted to test the psychometric characteristics (internal consistency, discriminant, convergent and structural validities) of the Lithuanian version of the Career decision-making difficulties questionnaire (Gati et al., 1996) in a sample of Lithuanian students (N = 255). The results revealed that the Lithuanian version of Career decision-making difficulties has good internal consistency. Adequate convergent validity was confirmed by finding statistically significant positive relationships with indecisiveness, and discriminant validity was confirmed by finding statistically significant negative relationships with career self-efficacy. Finally, structural validity was confirmed by confirmatory factor analysis, which revealed that a 10-factor structure was the most appropriate. The results of the research showed that the Lithuanian version of the Career decision-making difficulties questionnaire is a suitable measurement tool, but further studies on the evaluation of the scale are needed.
Phytochemical analysis of Aronia melanocarpa and ×Sorbaronia fallax fruit
Authors: Mezhenskyj V. M. , Shevchuk L. M. , Kovalchuk S. P. , Havryliuk O. S. , Levchuk L. M. , Babenko S. M. , Vintskovska Y. Y. 
Published: May 2024

Aronia melanocarpa (Michx.) Elliott, ×Sorbaronia fallax (C. K. Schneid.) C. K. Schneid. nothosubsp. fallax, and ×Sorbaronia fallax nothosubsp. mitschurinii (A. Skvortsov & Maitul.) A.Stalažs, belonging to the Rosaceae family, are grown as fruit plants. They are known to horticulturists as garden chokeberry or black chokeberry. The fruit of these species is the richest source of biophenols in the plant kingdom and suitable raw material for the production of functional foods with high nutraceutical value. The work aimed to examine the basic and polyphenolic composition of fruit chokeberry and rowan-chokeberry hybrids of different taxonomic groups. Experimental plants were grown at the orchard of the National University of Life and Environmental Sciences of Ukraine in the Kyiv region. Fruit of 10 cultivars developed in Belorussia, the Czech Republic, Finland, Russia, Ukraine, and the USA were collected during 2020 and 2021. The fruit was analyzed for dry matter, soluble solids, sugars, pectin substances, organic titratable acidity, ascorbic acid, and biophenols. Chokeberry fruit contains on average 24.4–29.2% dry matter, 16.0–21.1% soluble solids, 6.5–8.9% sugars, 0.40–0.80% pectin, and 0.95–2.15% organic acids on raw material. Bioactive components of chokeberry fruit are ascorbic acid (24.7–45.9 mg/100 g), total polyphenols (998–4840 mg/100 g), including anthocyanidins (9–217 mg/100 g), flavonoids (23–1422 mg/100 g), and chalcones (9–59 mg/100 g). If the group ×S. fallax nothosubsp. mitschurinii cultivars is morphologically constant and like A. melanocarpa simple in leaf shape, then the group ×S. fallax nothosubsp. fallax cultivars was different in the morphology of leaves from lobate to pinnate and fruit color from purple to black in the study. Chokeberry fruit composition varied between each year and especially between taxonomic groups and cultivars. Fruit harvested in 2021 had the lowest dry matter, soluble solid, sugars, and ascorbic acid in comparison with 2020. In contrast, titrated acidity was consistent between years. The fruit of garden chokeberries is a good source of ascorbic acid. ×S. fallax cultivars with the exception ‘Titan’ are richer on ascorbic acid. The fruit of A. melanocarpa ‘Dwarf’ has the highest content of total polyphenols, flavonoids, and chalcones. There are significant differences between ×S. mitschurinii cultivars in biochemical content. Purple-fruited ‘Titan’ has the lowest content of all biologically active substances, than other cultivars belonging to the same ×S. fallax taxonomic group. The black-fruited ×S. fallax nothosubsp. fallax genotypes, including the first chokeberry cultivar ‘Vseslava’ of Ukrainian breeding, often have a high or the highest content of ascorbic acid, total polyphenols, anthocyanidins, flavonoids, and chalcones, which is valuable for garden chokeberry breeding.
Morphological features of the causative agent of chorioptic mange isolated from cattle
Authors: Melnychuk V. , Kovalenko S. , Yevstafieva V. , Korchan L. , Kone M. , Titarenko O. , Nikiforova O. 
Published: May 2024

Providing veterinary care against parasitic diseases is one of the factors that affect the possibility of effective and profitable introduction of the livestock sector. Chorioptic mange is one of the globally spread invasive diseases of cattle caused by persistent ectoparasites. The diagnosis of chorioptosis is based on the microscopic detection of mites in scrapings from the skin of the affected animal with mandatory identification of the parasites. The aim of the research was to investigate the morphological features and metric parameters of Chorioptes mites isolated from cattle. Mites isolated from cattle were morphometrically identified as Chorioptes texanus. Morphological features of male Ch. texanus mites include peculiarities in the structure of the opisthosomal lobes and of the setae located on the opisthosomal lobes, opisthosoma and tarsus of leg III. 14 morphometric parameters characterizing the general structure of the body (length, width and their ratio, length and width of the gnathosoma, length of the idiosoma, proterosoma, podosoma, propodosoma, metapodosoma, hysterosoma, opisthosoma, length and width of the propodosomal shield) were identified and suggested for use in identification of male and female Ch. texanus. In male mites of this species, 5 additional parameters were also determined, which describe the length and width of the opisthomal lobes, their ratio, the diameter of the adanal suckers and the distance between them. The morphological features, location and length of 6 setae, which are species-specific in Chorioptes mites, namely 4 setae of the opisthosomal lobe, 1 opisthosomal seta, 1 ventral seta of tarsus III, were described. The parameters of Ch. texanus eggs in the bodies of female mites and on the body of the host animal were determined. The scientific data obtained in this study expand the already existing data on the differential identification of Ch. texanus mites and proves their parasitism in cattle on the territory of Ukraine.
A pilot study on the impact of parenteral vaccination of free-roaming dogs within the rabies control framework in Ukraine
Authors: Makovska I. F. , Tsarenko T. M. , Cliquet F. , Dhaka P. , Korniienko L. Y. , Tabakovski B. , Chantziaras I. , Dewulf J. 
Published: May 2024

This pioneering study is prompted by the imperative to enhance our understanding of a constituent within Ukraine's rabies control strategy, specifically focusing on the vaccination of free-roaming canines against rabies with a local vaccine in certain endemic rabies areas. The cross-sectional study encompassed the capture, sterilization, deworming, and rabies vaccination processes in 160 free-roaming dogs, followed by the collection of blood samples to examine RABV-specific neutralising antibodies in 16 dogs (10% of the vaccinated population), captured from sectors (territories) with a higher density of population and with higher density of previously vaccinated free-roaming dogs. Half of the targeted samples comprised males (n = 8), while the remaining half consisted of females (n = 8). The median of virus-neutralising antibody level was 0.58 IU/mL, with a minimum protective threshold of 0.5 IU/mL. Antibody titers below the 0.5 IU/mL threshold were detected in 25.0% (2/8) of the male group, and in 62.5% (5/8) of the female group. Notably, male dogs exhibited a higher median antibody level of 0.66 IU/mL, compared to females, who presented a median level of 0.26 IU/mL. However, no statistically significant difference was found between the male and female groups (P = 0.36). In general, more than half of the tested population (56.3%) exceeded the 0.5 IU/mL protective threshold 4 months post-vaccination. The inadequate levels of antibodies neutralizing the rabies virus are likely a result of a confluence of factors, including stressors such as nutritional and temperature-related challenges, along with variations in the responses of individual immune systems. Considering the endemic rabies situation and large population of free-roaming dogs in Ukraine, we suggest repeated vaccination for free-roaming dogs against rabies one year after the previous vaccination. In perspective, we suggest conducting large-scale epidemiological studies to assess the impact of animal-related, vaccine-related, and environment-related parameters on the efficacy of rabies vaccines used in Ukraine.
Efficacy of yoga package on cognitive flexibility and attention in university girls: A single group pilot study
Authors: Tyagi Yashi , Singh Sandeep 
Published: May 2024

Executive functions and attention are key indicator of cognitive health. Cognitive flexibility, the ability to flexibly switch between tasks, is a core dimension of executive functions. Yoga helps to improve mental wellness, which consequently provides cognitive flexibility.This study aimed to determine the effect of yoga on cognitive flexibility and attention in university girls.Thirty healthy university girls (group mean ± SD; 18.27 ± 1.44) were enrolled as participants in the study. Trail Making Test (TMT) parts A and B were used to assess their cognitive flexibility whereas sustained attention was determined using Six Letter Cancellation Test (SLCT). The assessments were taken at baseline and after three months of yogic practices. Statistical analysis was performed by paired t-test to examine the effect of yoga on cognitive flexibility and attention in university girls.There was a significant decrease in time taken to complete TMT part A (t= 4.33; P&#60;0.05) and a significant increase in total attempts (t= -2.75; P&#60;0.05) and net attempts (t=-2.80; P&#60;0.01) in six letter cancellation test after three months of yoga practice.The results suggest that yoga improves visual search ability and motor speed skills and hence cognitive flexibility and attention in university girls.
Flipped classroom approach for trauma education: Attitudes of participants towards pre-course assignments before the advanced trauma life supports (ATLS) instructor course
Authors: Ray Amita , Misra Mahesh Chandra , Jain Vinod , Ghosh Sudip 
Published: May 2024

A flipped classroom approach in principle, denotes pre-course engagement for an upcoming educational course. Although never used in trauma education, other educational literature is resplendent with the beneficial effects of pre-course engagement on the learning outcomes of the course itself. In this article we share the attitudes and perspectives of prospective Advanced Trauma Life Supports Instructors towards pre-course assignments to see whether this works in the field of trauma education.After an online pre-course session, we administered a validated questionnaire to 100 participants. The questionnaire had 4 categories - the first dealing with participants’ characteristics and the rest with their attitude and perspectives towards the pre-course sessions. The last category included three open ended questions for qualitative analysis to explain the attitudes of the participants.The participants showed a significantly positive attitude (p&#60;0.029) towards this flipped classroom approach. The reasons cited were “effective sensitization”, “adequate feedback”, “peer learning” “user friendly platform” “enjoyable” and “relevance”. A significantly higher level of agreement with the questionnaire statements was seen amongst the private sector doctors as compared to those working in public sector medical colleges (p = 0.004). Same was observed amongst clinical specialists as compared to pre or para clinical specialists (p = 0.001). The Questionnaire had a Cronbach’s alpha of 0.86.The study concludes that a flipped classroom approach can work well in trauma education. A tailored approach, depending upon participant characteristics, may be needed to enhance the relevance of a flipped classroom approach.
Personal Hygiene as Scabies Factors Incidence in the Institute Rehabilitation Center of the Vagrants, Scrounger and Mental Disabilities in South Sumatra Region
Authors: Haniifa Rahmadita Zinda 
Published: May 2024

Introduction: Scabies, caused by the mite Sarcoptes scabiei, is a highly contagious skin infestation. Poor personal hygiene often contributes to its prevalence. This study aims to identify specific aspects of personal hygiene that influence the incidence of scabies among residents of the Institute Rehabilitation Center of The Vagrants, Scroungers, and Individuals with Mental Disabilities in the South Sumatra Region. Methods: This observational-analytic study employed a case-control design. Data collection involved clinical records, observations, and questionnaire-based interviews. A total of 160 occupants, comprising 80 cases and 80 controls, were selected through simple random sampling. Data analysis utilized chi-square test and multiple logistic regression tests. Results and Discussion: Chi-square analysis revealed significant associations (p-value = 0.000) between scabies incidence and bathing habits, cleanliness of mattresses and bed linen, cleanliness of clothing, and open defecation behavior. Multiple logistic regression indicated that open defecation behavior (OR = 56.336; 95% CI = 17.281 – 158.500) was the primary personal hygiene factor influencing scabies incidence. Thus, maintaining proper open defecation practices is crucial for residents' hygiene and health. Conclusion: Poor personal hygiene practices, including inadequate bathing habits, unclean bedding, dirty clothing, and open defecation behavior, contribute to the occurrence of scabies. Effective education and counseling by healthcare professionals are essential for promoting better hygiene practices among residents.
FORMALIZATION OF THE PROCEDURE FOR ASSESSING THE ELECTRIC SUPPLY EFFICIENCY IN WORKSHOP NETWORKS OF INDUSTRIAL ENTERPRISES
Authors: Popov Vladimir , Zabolotnyi Anatolii , Dyachenko Vera , Fedosha Denys , Prykhno Valeriia 
Published: May 2024

There is defined that the efficiency of workshop power supply networks largely determines the efficiency of the power supply system of the industrial enterprise as a whole and is determined by minimizing the reduced costs, which have two components: capital investments and the cost of electricity losses in workshop networks. Calculating the reduced costs during a technical and economic comparison of options is a labor-intensive task, since there is a large variability in the choice of circuit design, the choice of cross-sections of the conductors of the supply and distribution workshop network, as well as taking into account the design features of the workshop network.
The analysis of the characteristics of the efficiency factors of workshop power supply was carried out. The basic components of the effective functioning of the workshoppower supply circuit are identified, namely: discreteness of electrical equipment; its placement in the workshop; operating modes of current-using equipment (CUE); loading schedule; ratio of the cost of electricity and the unit cost of workshop network elements.
There has been determined that in any workshop power supply scheme, the duration of switching CUE on the electric power supply (CUE with a constant and variable operating mode), as well as the shape of the load schedule, largely determines the efficiency of its operation.
Obtained results of a numerical experiment, when performing design of workshop networks in the DIPROPROM design institution (Zaporozhye), showed the effectiveness (3-7%) in determining the operational characteristics of workshop networks in comparison with existing engineering methods.