bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building a robust pharmacy research program: Reflections from a large healthcare system not affiliated with a college of pharmacy
Authors: Herges Joseph R. , Wieruszewski Erin D. , Barreto Jason N. , Taraba Jodi L. , Barreto Erin F. , Oyen Lance J. , Nei Andrea M. , Wieruszewski Patrick M. , Thurber Kristina M. , Schramm Garrett E. , Formea Christine M. , Rudis Maria I. 
Published: May 2024

AbstractProfessional standards for academic health care system pharmacy departments and clinical pharmacists advocate for research and scholarly activities. Developing and sustaining a research program in a clinical pharmacy department is challenging. Over the span of a decade, a robust pharmacy research program was developed in an academic medical center not affiliated with a college of pharmacy. The aim of this manuscript is to provide a framework suitable for scaling research in pharmacy departments within an academic medical center. Objectives to accomplish the aim includes describing the structure and evolution of the clinical pharmacy department research program, listing measurable outputs and achievements of the pharmacists and the program and describing the barriers encountered and solutions that were enacted to overcome them. Elements critical to building and sustaining a research program in the pharmacy department included long‐term commitment from within the department, a departmental research infrastructure, support from institutional leadership, research funding from the institution, and a growth mindset in accordance with company initiatives to support evolving research needs. A research curriculum was developed for pharmacy residents and pharmacists, created electronic tools for research proposal scientific reviews and allocation of funds, and established departmental research career development awards that allowed for protected time to pursue research and professional development. Over the first 10 years of the program, publication rates grew more than three‐fold, faculty appointments and promotions increased approximately five‐fold, and pharmacist investigators obtained extramural federal funding. Further offsetting clinical workload relative to dedicated research time remains a challenge. The experience and success at this academic medical center suggest it is feasible to develop a robust, sustainable clinical pharmacy department research program.
Social communication and restricted, repetitive behavior as assessed with a diagnostic tool for autism (ADOS‐2) in women with anorexia nervosa
Authors: Saure Emma , Laasonen Marja , Kylliäinen Anneli , Hämäläinen Sini , Lepistö‐Paisley Tuulia , Raevuori Anu 
Published: May 2024

AbstractObjectiveIn anorexia nervosa (AN), the traits of autism spectrum disorder (ASD) are associated with poor outcomes. However, the subtle nature of these characteristics remains poorly understood. We investigated the in‐depth patterns of ASD traits using Autism Diagnostic Observation Schedule‐Second Edition (ADOS‐2) in women with AN.MethodsOf 28 women with ICD‐10 AN, 16 (age 19–30 years) participated in the ADOS‐2, a video‐recorded, semistructured diagnostic assessment for social communication and interaction and restricted, repetitive behaviors and interests related to ASD. None of the participants had previously been diagnosed with ASD. Other measurements included the Eating Disorder Examination Questionnaire and the Wechsler Abbreviated Scale of Intelligence‐IV.ResultsFive individuals (18% of all, 31% of those assessed) scored above the cutoff for autism in ADOS‐2. They had challenges in social communication and interaction, manifesting as sustained difficulties in social relationships and deficits in conversation skills. Few described being frequently misunderstood by others, including in the eating disorder treatment settings. Three individuals showed prominent restricted and repetitive behaviors such as ritual seeking, eating‐related routines, sensory sensitivity related to food texture and selective eating, and intense interest in specific topics. The mean duration of AN in women above the cutoff was twice as long compared with those below (12.3 vs. 6.2 years).DiscussionThe ASD‐related characteristics and behavior appear to contribute to the manifestation and duration of AN in a subgroup of women. Among these women, the traits of ASD appear to be mixed with eating disorder symptoms, which should be taken into account in the treatment.
Gallai‐like characterization of strong cocomparability graphs
Authors: Huang Jing 
Published: May 2024

AbstractStrong cocomparability graphs are the reflexive graphs whose adjacency matrix can be rearranged by a simultaneous row and column permutation to avoid the submatrix with rows . Strong cocomparability graphs form a subclass of cocomparability graphs (i.e., the complements of comparability graphs) and can be recognized in polynomial time. In his seminal paper, Gallai characterized cocomparability graphs in terms of a forbidden structure called asteroids. Gallai proved that cocomparability graphs are precisely those reflexive graphs which do not contain asteroids. In this paper, we give a characterization of strong cocomparability graphs which is analogous to Gallai's characterization for cocomparability graphs. We prove that strong cocomparability graphs are precisely those reflexive graphs which do not contain weak edge‐asteroids (a weaker version of asteroids). Our characterization also leads to a polynomial time recognition algorithm for strong cocomparability graphs.
ePortfolios: Enhancing confidence in student radiographers' communication of radiographic anatomy and pathology. A cross‐sectional study
Authors: Dolic Magdalena , Peng Yaxuan , Dhingra Keshav , Lee Kristal , McInerney John 
Published: May 2024

AbstractIntroductionIn 2020, the Medical Radiation Practice Board of Australia made several revisions to its professional capabilities. To address this, medical radiation practitioners, including diagnostic radiographers, are required to escalate urgent findings in all radiographic settings. However, the confidence of radiographers in articulating descriptions of radiographic findings varies despite this requirement. This cross‐sectional study explores how the implementation of eportfolio affects student self‐perceived confidence in identifying and describing radiographic findings in both an academic and a clinical setting.MethodsA Qualtrics survey was distributed to second‐year radiography students who had used eportfolios. The survey comprised of four questions using a Likert‐scale and one open‐ended question. Quantitative data were analysed using the Wilcoxon signed‐rank test and qualitative data was thematically assessed.ResultsOverall, 55 of 65 radiographic students (85%) completed the survey. Confidence (strongly agree and agree) decreased from 89% to 74% between academic and clinical environments when identifying abnormalities, and 89% to 73% when describing findings. This finding highlights the challenges students face when in the clinical environment. Wilcoxon signed rank test analysed a statistically significant relation between the two environments (P < 0.05). However, the relationship between identifying and describing skills was not statistically significant (P > 0.05). Following a review of the qualitative data, three recurring themes were identified among responses.ConclusionePortfolios assist in improving confidence in identification and description of radiographic abnormalities, particularly in an academic setting. The clinical environment presents unique challenges which may limit student clinical performance; however, this requires further investigation.
Talus‐derived reference coordinate system for 3D calcaneal assessment: A novel approach to improve morphological measurements
Authors: Wakker Alexander M. , Verhofstad Michael H. J. , Visser Jacob J. , Van Vledder Mark G. , Van Walsum Theo 
Published: May 2024

AbstractIn 3D‐analysis of the calcaneus, a consistent coordinate system aligned with the original anatomical directions is crucial for pre‐ and postoperative analysis. This importance stems from the calcaneus's key role in weight‐bearing and biomechanical alignment. However, defining a reliable coordinate system based solely on fractured or surgically reconstructed calcanei presents significant challenges. Given its anatomical prominence and consistent orientation, the talus offers a potential solution to this challenge. Our work explores the feasibility of talus‐derived coordinate systems for 3D‐modeling of the calcaneus across its various conditions. Four methods were tested on nonfractured, fractured and surgically reconstructed calcanei, utilizing Principal Component Analysis, anatomical landmarks, bounding box, and an atlas‐based approach. The methods were compared with a self‐defined calcaneus reference coordinate system. Additionally, the impact of deviation of the coordinate system on morphological measurements was investigated. Among methods for constructing nonfractured calcanei coordinate systems, the atlas‐based method displayed the lowest Root Mean Square value in comparison with the reference coordinate system. For morphological measures like Böhler's Angle and the Critical angle of Gissane, the atlas talus‐based system closely aligned with ground truth, yielding differences of 0.6° and 1.2°, respectively, compared to larger deviations seen in other talus‐based coordinate systems. In conclusion, all tested methods were feasible for creating a talus derived coordinate system. A talus derived coordinate system showed potential, offering benefits for morphological measurements and clinical scenarios involving fractured and surgically reconstructed calcanei. Further research is recommended to assess the impact of these coordinate systems on surgical planning and outcomes.
4670‐PPI OLEDoS pixel circuit design for wide data voltage range in a 5 V 0.13 μm CMOS process
Authors: Shin Hyeon‐Jun , Kim Yong‐Duck , Choi Byong‐Deok 
Published: May 2024

AbstractOLEDoS displays hold great promise for AR/VR applications, but the ultra‐high pixel density required for microdisplays, exceeding several thousand PPI, presents significant challenges for pixel circuit design. Above all, the maximum OLED current of each OLEDoS sub‐pixel is extremely low, on the order of several nanoamperes or less, resulting in a data voltage range narrower than a few hundred millivolts. Consequently, for example, when expressing 10‐bit grayscale, designing data driver circuits to divide the data voltage range into 1024 levels becomes exceedingly challenging. Furthermore, circuit techniques that compensate for variations in transistor characteristics are nearly inapplicable due to the ultra‐small pixel area. This paper proposes a pixel circuit design method to expand the data voltage range for a 4670‐PPI OLEDoS display while considering current uniformity. The effectiveness of the proposed pixel circuit was verified through measurements on 40 × 120 pixel arrays fabricated in a 5 V 0.13 μm CMOS process.
Point‐of‐Care Ultrasound Psychomotor Learning Curves
Authors: Breunig Mike , Chelf Cynthia , Kashiwagi Deanne 
Published: May 2024

ObjectivesUse of point‐of‐care ultrasound (POCUS) in clinical medicine and inclusion in medical training is increasing. Some professional societies recommend that 25–50 POCUS examinations be completed for each application learned; however, the amount of practice required is not well studied. As such, a better understanding of the learning curves of POCUS psychomotor skills is needed. This systematic review characterizes the learning curves for POCUS psychomotor skill acquisition.MethodsWith the assistance of a research librarian, the available literature through August 28, 2023, was identified. The titles and abstracts, and then the full text were reviewed by two reviewers to screen for inclusion. All studies included after full‐text review then underwent data extraction and analysis.ResultsThe search identified 893 unique studies. Forty‐five studies underwent full‐text review, with 17 meeting full inclusion criteria. Substantial heterogeneity was noted in study design, duration of education, number and type of learners, and methods for statistical analysis. Clear and validated definitions for learning endpoints, such as plateau points or competency, are lacking. Learning curves and endpoints differ for different applications of POCUS.ConclusionThe results are overall supportive of the recommendations to complete 25–50 examinations per application of POCUS learned. However, specific applications require more practice than others. Certain applications, such as cardiac and the Focused Assessment with Sonography in Trauma (FAST) exams, are closer to 50; while others, such as soft tissue, airway, and eye require no more than 25.
Central cone design demonstrates greater micromotion compared to keel design in cementless tibial baseplates: A biomechanical analysis
Authors: Luo T. David , Sogbein Olawale A. , MacDonald Brett M. , Masse Jarrett A. , Willing Ryan T. , Lanting Brent A. 
Published: May 2024

AbstractPurposeThe purpose of this study was to compare micromotion of two new cementless tibial baseplates to a cementless design with well‐published clinical success.MethodsThree cementless tibial baseplate designs (fixed‐bearing [FB] with keel and cruciform pegs, rotating‐platform with porous central cone and pegs, FB with cruciform keel and scalloped pegs) were evaluated on sawbone models. Loading was applied to the baseplate at a rate of 1 Hz for 10,000 cycles, which represents 6–8 weeks of stair descent. This time frame also represents the approximate time length for the induction of biologic fixation of cementless implants. Compressive and shear micromotion at the sawbone–implant interface were measured.ResultsAt the end of the loading protocol, the central cone rotating‐platform design exhibited greater micromotion at the anterior (p < 0.001), posterior (p < 0.001) and medial locations (p = 0.049) compared to the other two implants. The central cone design also exhibited greater translational micromotion in the sagittal plane at the medial (p = 0.001) and lateral locations (p = 0.034) and in the coronal plane anteriorly (p = 0.007).ConclusionThe cementless central cone rotating‐platform baseplate demonstrated greater vertical and translational micromotion compared to the two FB baseplates with a keel underloading. This may indicate lower initial mechanical stability in implants without a keel, which possibly affects osseointegration. The implication of this is yet unknown and requires further long‐term clinical follow‐up to correlate these laboratory findings.Level of EvidenceV (biomechanical study).
Higher diagnostic value of next‐generation sequencing versus culture in periprosthetic joint infection: A systematic review and meta‐analysis
Authors: Su Shilong , Wang Ruideng , Zhou Rubing , Bai Jinwu , Chen Zhengyang , Zhou Fang 
Published: May 2024

AbstractBackgroundThe next‐generation sequencing (NGS) has developed rapidly in the past decade and is becoming a promising diagnostic tool for periprosthetic infection (PJI). However, its diagnostic value for PJI is still uncertain. The purpose of this systematic review and meta‐analysis was to evaluate the diagnostic value of NGS compared to culture.MethodsIn this systematic review and meta‐analysis, electronic databases including PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science and clinicaltrials.gov were searched for studies from inception to 12 November 2023. Diagnostic parameters, such as sensitivity, specificity, diagnostic odds ratio and area under the summary receiver‐operating characteristic (SROC) curve (AUC), were calculated for the included studies. A systematic review and meta‐analysis was performed.ResultsA total of 22 studies with 2461 patients were included in our study. The pooled sensitivity, specificity and diagnostic odds ratio of NGS were 87% (95% confidence interval [CI]: 83–90), 94% (95% CI: 91–96) and 111 (95% CI: 70–177), respectively. On the other hand, the pooled sensitivity, specificity and diagnostic odds ratio of culture were 63% (95% CI: 58–67), 98% (95% CI: 96–99) and 93 (95% CI: 40–212), respectively. The SROC curve for NGS and culture showed that the AUCs are 0.96 (95% CI: 0.94–0.98) and 0.82 (95% CI: 0.79–0.86), respectively.ConclusionThis systematic review and meta‐analysis found NGS had higher sensitivity and diagnostic accuracy but slightly lower specificity than culture. Based on the pooled results, we suggested NGS may have the potential to be a new tool for the diagnosis of PJI.Level of EvidenceLevel IV.
Kinematics of 90° change of direction in young football players: Insights for ACL injury prevention from the CUTtheACL study on 6008 trials
Authors: Della Villa Francesco , Di Paolo Stefano , Crepaldi Matteo , Santin Piefrancesco , Menditto Ilaria , Pirli Capitani Luca , Boldrini Lorenzo , Ciampone Luca , Vassura Gabriele , Bortolami Antonio , Bosi Andrea Nicolò , Grassi Alberto , Zaffagnini Stefano 
Published: May 2024

AbstractPurposeTo investigate the 90° change of direction (COD) task in an extensive cohort of competitive healthy football players within the CUTtheACL study and to provide normative values and differences between males and females for full‐body kinematics based on two‐dimensional (2D) video analysis and scoring system.MethodsOne‐thousand‐and‐two competitive football (soccer) players (age 16.3 ± 2.8 years, 264 females) were prospectively enroled. Each player performed three preplanned 90° COD tasks per limb. The 2D evaluation was performed through objective measures (collected through three high‐speed cameras) of frontal and sagittal plane joint kinematics at the cut initial foot contact (IC) and maximum knee flexion angle. A previously published scoring system was adopted to measure the movement quality of the COD task. The scoring system included five criteria (limb stability [LS], pelvis stability [PS], trunk stability [TS], shock absorption [SA], movement strategy [MS]) ranked from 0/2 (nonadequate) to 2/2 (adequate) with a maximum score of 10/10. Normative data were provided for all the variables; statistical differences between male and female players were investigated (p < 0.05).ResultsA total of 6008 valid attempts were included. Frontal plane knee projection angle (FPKPA) at initial contact was 24.4 ± 9.8° (95th percentile: FPKPA > 40°). The total score was ≤4/10 in 71.2% of the trials, the lowest subscores were LS and PS. Female players showed different movement patterns with lower hip and trunk flexion both at IC and maximum knee flexion angle (p < 0.01, ES = 0.41–0.64). Female players also showed worse scores than males in SA, MS and total score (p < 0.01).ConclusionFemale players seem more prone to stiffer lower limb strategy and greater pelvis–trunk frontal plane instability than males. Clinicians could adopt normative data and sex‐specific differences in players' movement techniques to improve ACL injury risk mitigation protocols.Level of EvidenceLevel IV.
Picosecond alexandrite laser treatment of nevus of Ota in children
Authors: Zhao Wenwen , Yang Ying , Shi Hualing , Guo Lifang , Ding Hui , Zhen Huiying , Lin Tong , Ge Yiping 
Published: May 2024

AbstractBackgroundThe picosecond alexandrite laser has been safely and effectively used to treat the nevus of Ota in adults. However, limited data are available for children.ObjectiveTo investigate the efficacy, safety, and correlative influencing factors of a 755nm picosecond alexandrite laser in the treatment of nevus of Ota in children.MethodsWe retrospectively analyzed Chinese children with nevus of Ota who received a 755nm picosecond alexandrite laser treatment in a tertiary dermatological hospital.ResultA total of 305 pediatric patients received an average of two treatments achieving an average of 79% pigment clearance. After the first treatment, 22 patients achieved complete clearance (95%–100%), and 72 patients achieved excellent response (75%–94%), with an average initial efficacy of 63% lesion clearance. Treatment at an early age achieved better initial efficacy (0‐ to 12‐month group >1‐ to 6‐year group, 6‐ to 12‐year group). And 0‐ to 12‐month group achieved better final efficacy. More treatment sessions also increased the final efficacy. Both initial efficacy and final efficacy were better when treating a darker lesion. The incidence of complications was 12.1%, with 10.8% being post‐inflammatory hyperpigmentation and 1.3% being hypopigmentation. The rate of recurrence was 6.6%.LimitationRetrospective study.ConclusionA 755nm picosecond alexandrite laser is safe and effective in treating nevus of Ota in children. Younger to initiate treatment, darker lesions, and more treatments are positively associated with better pigmentation clearance.
A BETTER LEADERSHIP COMPASS
Authors: Crossan Mary , Crossan Corey , Furlong Bill 
Published: May 2024

AbstractMary Crossan is a Distinguished University Professor and Professor of Strategic Leadership at the Ivey Business School, Western University. Corey Crossan is a research and teaching fellow at The University of Oxford with The Oxford Character Project. Bill Furlong is an executive in residence at the Ivey Business School, and a co‐founder with Mary Crossan of Leader Character Associates Inc. In this article, “the story we tell is about a paradigm shift to elevate character alongside competence in our work and our lives as a foundation for transformation.” Their Figure 1, the Leader Character Framework, depicts judgment in the middle, while radiating out are the terms (with brief explanations), transcendence, drive, collaboration, humanity, humility, integrity, temperance, justice, accountability, and courage. These terms are further delineated in the extensive Virtues and Vices Index Table 1. They also present a variety of character‐related questions, which in their words include: Are we operating at the highest level of understanding how character influences our well‐being and sustained excellence? Do we believe we can change? Does our lifestyle enable us to change our character? Do your peers enable or undermine your character? Do the cultural norms of your organization and society enable or undermine your character?
AWARENESS: A TOOL FOR BURNOUT IMMUNITY
Authors: Wiens Kandi 
Published: May 2024

AbstractThe author is a senior fellow at the University of Pennsylvania Graduate School of Education, a well‐known researcher and speaker on burnout, emotional intelligence, and resilience; and developer of the Burnout Quiz. The article discusses burnout in the context of awareness and self‐awareness, based on her research. She contends that “leaders who display social awareness—the ability to accurately understand the impact of our emotions, thoughts, and behaviors on others, and to understand and share the feelings of others—are better at decision‐making, coaching and engaging their teams, and communication and collaboration.” However, “when leaders are burned out, it’s never just an individual problem. Entire teams and even organizations can suffer when leaders lose motivation and energy, struggle with their ability to influence people, make poorer (and often slower) decisions, and spread an attitude of cynicism throughout organizations.” She discusses what she terms “core burnout immunity awareness skills.” These are, in her words, Awareness of what triggers your workplace stress; Awareness of what increases your sensitivity to stress; Awareness of your tipping point between good stress and bad stress; and Awareness of your burnout risk level.