bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of storage lifetime of rubber materials for flexible joint elastomers
Authors: Liu Wenzhi , Deng Yueqiu , Qi Pengcheng , Yin Xiaohao , Yang Xufeng , Gao Liqi 
Published: May 2024

Abstract
To investigate the aging performance and storage lifetime of rubber materials used in flexible joint elastomers for solid rocket engines, a compression permanent deformation was used as the performance evaluation index to conduct aging tests on the elastic specimens of joint rubber materials at different temperatures. The results showed that the compression permanent deformation increased with the aging time and temperature, and the value of compression permanent deformation was greater in the initial stage of aging than in the later stage. Based on the regularity of material aging performance, the storage lifetime of rubber materials at room temperature of 25°C is extrapolated to be approximately 17.35 years through the linear equation of aging kinetics. Given that the aging mechanism remains unchanged, the calculation based on the principle of time-temperature equivalence reveals that as the aging temperature of the rubber material increases, the accelerated aging time to reach the regular storage lifetime becomes faster. Aging for 11.25 days at 140°C is equivalent to storing for this rubber material 15 years at 25°C. This research provides references for the future design, manufacturing, maintenance, and storage reliability of flexible joints.
CMS Level-1 trigger Data Scouting firmware prototyping for LHC Run-3 and CMS Phase-2
Authors: Ardino Rocco , Deldicque Christian , Dobson Marc , Gigi Dominique , Giorgetti Sabrina , James Thomas Owen , Lazzari Miotto Giovanna , Meschi Emilio , Migliorini Matteo , Petrucciani Giovanni , Rabady Dinyar , Racz Attila , Sakulin Hannes , Zejdl Petr ,   the CMS collaboration
Published: May 2024

Abstract
A novel Data Acquisition (DAQ) system, known as Level-1 Data Scouting (L1DS), is being introduced as part of the Level-1 (L1) trigger of the CMS experiment. The L1DS system will receive the L1 intermediate primitives from the CMS Phase-2 L1 trigger on the DAQ-800 custom boards, designed for the Phase-2 central DAQ. Firmware is being developed for this purpose on the Xilinx VCU128 board, with features similar to one half of the DAQ-800, and validated in a demonstrator for LHC Run-3. This contribution describes the firmware development in view of the target design for the DAQ-800.
Decadal preference of seasonal ENSO transition through a southern hemisphere climate mode
Authors: Srivastava Shikhar , Chakraborty Arindam , Murtugudde Raghu 
Published: May 2024

Abstract
El Niño Southern Oscillation (ENSO) is the leading interannual coupled climate mode in the tropical Pacific. The seasonal transition of ENSO from boreal winter to the following summer can significantly affect the global climate. One of the major hurdles in understanding the seasonal transition of ENSO is the spring predictability barrier. Here, we show that ENSO’s seasonal transition is modulated by a multidecadal climate mode of boreal spring sea-level pressure (SLP) in the extratropical Southern Hemisphere. This ENSO transition mode (ETM), when characterised by a decrease in SLP and associated clockwise circulation of the surface winds centred over the southeastern subtropical Pacific Ocean, produces westerly anomalies at the equator. These wind anomalies in the equatorial eastern Pacific aid the seasonal warming of Niño3.4 sea surface temperature anomalies (N34SST) from boreal winter to the following summer. The ETM time series shows prominent multidecadal variations at around 50 years. This creates a conducive environment for alternate cold and warm seasonal transitions leading to multidecadal variations in boreal summer N34SST. Thus, ETM provides a physical insight into the seasonal transition of ENSO and leads to a new paradigm for ENSO evolution beyond its peak. This has implications for seasonal ENSO forecasts and decadal climate predictions.
A unifying quantum speed limit for time-independent Hamiltonian evolution
Authors: Chau H F , Zeng Wenxin 
Published: May 2024

Abstract
Quantum speed limit (QSL) is the study of fundamental limits on the evolution time of quantum systems. For instance, under the action of a time-independent Hamiltonian, the evolution time between an initial and a final quantum state obeys various mutually complementary lower bounds. They include the Mandelstam–Tamm (MT) bound, the Margolus–Levitin (ML) bound, the Luo–Zhang bound, the Lee–Chau (LC) bound together with the dual ML bound introduced by Ness and coworkers. Here we show that the MT bound can be obtained by optimizing the LC bound over a certain parameter. More importantly, we report a QSL that includes all the above bounds as special cases before optimizing over the physically meaningless reference energy level of a quantum system. This unifying bound depends on a certain parameter p. For any fixed p, we find all pairs of time-independent Hamiltonian and initial pure quantum state that saturate this unifying bound. More importantly, these pairs allow us to compute this bound accurately and efficiently using an oracle that returns certain pth moments related to the absolute value of energy of the quantum state. Moreover, this oracle can be simulated by a computationally efficient and accurate algorithm for finite-dimensional quantum systems as well as for certain infinite-dimensional quantum states with bounded and continuous energy spectra. This makes our computational method feasible in a lot of practical situations. We further compare the performance of this bound for the case of a fixed p as well as the case of optimizing over p with existing QSLs. We find that if the dimension of the underlying Hilbert space is

≲

2000

, our unifying bound optimized over p can be computed accurately in a few minutes using Mathematica code with just-in-time compilation in a typical desktop. Besides, this optimized unifying QSL is at least as good as all the existing ones combined and can occasionally be a few percent to a few times better.
Relevance of Behavioral Research in the Evolving State of Anti-obesity Medications: Is the Glass Half Empty or Half Full?
Authors: Martin Michelle Y , Rogers Renee J 
Published: May 2024

Abstract
Obesity continues to be a significant public health challenge. While weight loss medications have been studied and available for several years, the newest generation of highly effective anti-obesity medications (AOMs) will shift how behavioral science professionals approach obesity treatment and research. With the unique skill set of behavioral science professionals, this commentary suggests ways to integrate behavioral science into the rapidly evolving landscape of AOM use to accelerate better obesity care and generate new lines of research. The goal of this commentary is to stimulate discussion and encourage responsive and relevant action to improve population health.
Study on the Correlation Between Cerebral Vascular Variation and Hypertension
Authors: Fan Jia-cheng , Hui Ying , Yang Ying-ping , Zhao Yan-sheng , Li Meng-Ning , Ren Wei , Yang Zhan-jun 
Published: May 2024

Abstract

OBJECTIVE
To investigate the association between cerebral vascular variation and hypertension in adults.

METHODS
Using a cross-sectional study, the current and retired employees of Kailuan Group who participated in the physical examination of Kailuan General Hospital and underwent magnetic resonance examination in 2020–2022 were taken as the observation objects, and a total of 1,029 people finally met the inclusion and exclusion criteria. The observation objects were divided into 4 groups: no cerebral vascular variation, only vertebral artery hypoplasia (VAH), only incomplete posterior Circle of Willis (ipCoW), and combined variations (VAH + ipCoW). Binary logistic regression models were used to explore the effects of different types of cerebral vascular variation on hypertension.

RESULTS
The mean age of the study population was 55.2 ± 11.4 years. The percentages in no cerebral vascular variations, VAH only, ipCoW only, and combined variations groups were 21.1%, 11.5%, 46.8%, and 20.6%, respectively. Using hypertension as the dependent variable and cerebral vascular variation type as the independent variable, and adjusting for multiple confounders, the results showed that the presence of both VAH and ipCoW was positively associated with hypertension risk (OR = 2.410, 95% CI = 1.401–4.146). Stratified analysis showed that the association was more pronounced in people younger than 55 (OR = 4.437, 95% CI = 1.891–10.406), whereas no significant association was found in people older than 55 (P &gt; 0.05).

CONCLUSIONS
There is a positive correlation between cerebral vascular variation and hypertension, and this association is predominantly observed in the younger population.
AnnoView enables large-scale analysis, comparison, and visualization of microbial gene neighborhoods
Authors: Wei Xin , Tan Huagang , Lobb Briallen , Zhen William , Wu Zijing , Parks Donovan H , Neufeld Josh D , Moreno-Hagelsieb Gabriel , Doxey Andrew C 
Published: May 2024

Abstract
The analysis and comparison of gene neighborhoods is a powerful approach for exploring microbial genome structure, function, and evolution. Although numerous tools exist for genome visualization and comparison, genome exploration across large genomic databases or user-generated datasets remains a challenge. Here, we introduce AnnoView, a web server designed for interactive exploration of gene neighborhoods across the bacterial and archaeal tree of life. Our server offers users the ability to identify, compare, and visualize gene neighborhoods of interest from 30 238 bacterial genomes and 1672 archaeal genomes, through integration with the comprehensive Genome Taxonomy Database and AnnoTree databases. Identified gene neighborhoods can be visualized using pre-computed functional annotations from different sources such as KEGG, Pfam and TIGRFAM, or clustered based on similarity. Alternatively, users can upload and explore their own custom genomic datasets in GBK, GFF or CSV format, or use AnnoView as a genome browser for relatively small genomes (e.g. viruses and plasmids). Ultimately, we anticipate that AnnoView will catalyze biological discovery by enabling user-friendly search, comparison, and visualization of genomic data. AnnoView is available at http://annoview.uwaterloo.ca
Domestication reduces caterpillar response to auditory predator cues
Authors: Lee Zachary A , Baranowski Alex K , Cohen Caroline B , Pelletier Tyler S , Preisser Evan L 
Published: May 2024

Abstract
Domestication can lead to significant changes in the growth and behavior of organisms. While the threat of predation is a strong selective force in the wild, the relaxation or removal of this threat in captive-rearing environments selects for reduced sensitivity to biotic stressors. Previous work has documented such changes in other taxa, but no work has been done on domestication-related losses of predation risk sensitivity in insects. We exposed both wild and domesticated (&gt;50 generations in captivity) Lymantria dispar dispar (Lepidoptera: Erebidae) larvae to recordings of predators (wasp buzzing), nonpredators (mosquito buzzing), or no sound to compare the effects of predation risk on the two stocks. Wasp buzzing, but not mosquito buzzing, decreased survival of wild caterpillars relative to the control; domesticated caterpillars showed no such response. Domesticated L. dispar larvae appear to have reduced sensitivity to predation risk cues, suggesting that captive-reared insects may not always be analogs to their wild counterparts for risk-related behavioral studies.
Effects of flavoring additives on feed intake, growth performance, temperament, and markers of immune function for newly received feedlot cattle
Authors: Ahmad Mustaq , Seddon Yolande M , Blanch Marta , Penner Gregory B , Moya Diego 
Published: May 2024

Abstract
Ninety Angus × Hereford steers (259.9 ± 36.18 kg body weight [BW]) were used in a 56-d experiment to assess the effects of flavoring additives on feed intake, and stress and immune response of newly received feedlot cattle. Steers were homogenously distributed by BW into six pens equipped with an individual feed intake monitoring system, and pen was randomly assigned to one of three treatments (15 heads per pen; 30 heads per treatment): a standard feedlot receiving diet (CT), or the same diet with a flavoring additive comprised of either sweeteners (Luctarom Feedlot, SW) or a mix of basic tastes (Luctarom Feedlot Mix, MX) at 1 kg/mT. Pens were equipped with a feed intake monitoring system, while BW, chute behavior, flight speed, blood and saliva samples were collected bi-weekly, and hair samples were collected at 4-wk intervals during the study. Data were analyzed using a mixed-effects model for a pen study using individual animal records with repeated measures. There was a treatment × week interaction (P &lt; 0.01) where meal duration was greater in SW steers than MX and CT on week 3, and then CT on weeks 7 and 8. A trend for treatment × week interaction (P = 0.06) showed that the number of visits per day tended to be greater in SW than MX steers on weeks 4 and 5, and it tended to be greater in SW than MX and CT on week 5. The concentration of IL-6 was greater (P &lt; 0.01) on days 1 and 28 than on day 14. The IgM concentration was greater (P &lt; 0.01) on day 1 compared to days 14, 28, and 56. The concentration of haptoglobin was greater (P &lt; 0.01) on 14 than days 28, 42, and 56, and it was greater (P &lt; 0.01) on day 1 than days 42 and 56. The concentration of serum amyloid A was greater (P &lt; 0.01) on day 1 compared to the rest of sampling days. Fibrinogen concentration was greater (P &lt; 0.01) on day 1 compared to days 14 and 42. The neutrophil-to-lymphocyte ratio was greater (P &lt; 0.01) on days 42 and 56 compared to days 1 and 28, and greater (P &lt; 0.01) on day 14 compared to day 28. Hair and saliva cortisol concentrations were lower (P &lt; 0.01) on day 56 compared to days 1 and 28, respectively. The use of flavoring additives, particularly when based on sweeteners (SW), caused some changes in the feeding pattern of newly received steers. These changes, however, were not consistent over the 56-d feeding period and were not accompanied by a change in growth performance, temperament, biomarkers of stress, inflammation, or immune function.
The Genesis Effect: Digital Goods in the Metaverse
Authors: Yang Haiyang 
Published: May 2024

Abstract
This research shows that although the used and unused versions of a digital good (e.g., virtual apparel) are identical in every pixel and functionality, consumers tend to prefer the unused version. This “genesis effect” occurs because consumers tend to perceive used (vs. unused) digital goods as virtually contaminated and because being permanently listed as the first (vs. subsequent) owner in the ownership record can confer a greater sense of status. Specifically, in study 1, analyses of large-scale field data on purchases of digital goods in the metaverse showed that consumers paid substantially more to acquire the unused (vs. used) version of the same good. Studies 2–4 causally demonstrated the genesis effect and its underlying mechanism across metaverse product categories—participants were less likely to purchase digital goods described as used (vs. unused). Virtual contamination and virtual status jointly mediated the effect. Furthermore, being the first—at the genesis of a digital product’s usage history—was particularly special, such that participants were less sensitive to increases in the number of prior owners after the first one. Finally, showing participants that a used good had been digitally reconstituted attenuated the genesis effect. These findings add to the literature on consumer behavior in the metaverse and offer managerial insights on digital goods marketing.
Evaluation of the Glymphatic System in Schizophrenia Spectrum Disorder Using Proton Magnetic Resonance Spectroscopy Measurement of Brain Macromolecule and Diffusion Tensor Image Analysis Along the Perivascular Space Index
Authors: Abdolizadeh Ali , Torres-Carmona Edgardo , Kambari Yasaman , Amaev Aron , Song Jianmeng , Ueno Fumihiko , Koizumi Teruki , Nakajima Shinichiro , Agarwal Sri Mahavir , De Luca Vincenzo , Gerretsen Philip , Graff-Guerrero Ariel 
Published: May 2024

Abstract

Background and Hypothesis
The glymphatic system (GS), a brain waste clearance pathway, is disrupted in various neurodegenerative and vascular diseases. As schizophrenia shares clinical characteristics with these conditions, we hypothesized GS disruptions in patients with schizophrenia spectrum disorder (SCZ-SD), reflected in increased brain macromolecule (MM) and decreased diffusion-tensor-image-analysis along the perivascular space (DTI-ALPS) index.

Study Design
Forty-seven healthy controls (HCs) and 103 patients with SCZ-SD were studied. Data included 135 proton magnetic resonance spectroscopy (1H-MRS) sets, 96 DTI sets, with 79 participants contributing both. MM levels were quantified in the dorsal-anterior cingulate cortex (dACC), dorsolateral prefrontal cortex, and dorsal caudate (point resolved spectroscopy, echo-time = 35ms). Diffusivities in the projection and association fibers near the lateral ventricle were measured to calculate DTI-ALPS indices. General linear models were performed, adjusting for age, sex, and smoking. Correlation analyses examined relationships with age, illness duration, and symptoms severity.

Study Results
MM levels were not different between patients and HCs. However, left, right, and bilateral DTI-ALPS indices were lower in patients compared with HCs (P &lt; .001). In HCs, age was positively correlated with dACC MM and negatively correlated with left, right, and bilateral DTI-ALPS indices (P &lt; .001). In patients, illness duration was positively correlated with dACC MM and negatively correlated with the right DTI-ALPS index (P &lt; .05). In the entire population, dACC MM and DTI-ALPS indices showed an inverse correlation (P &lt; .01).

Conclusions
Our results suggest potential disruptions in the GS of patients with SCZ-SD. Improving brain’s waste clearance may offer a potential therapeutic approach for patients with SCZ-SD.
Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia
Authors: Radbel Jared , Meshanni Jaclynn A , Vayas Kinal N , Le-Hoang Oahn , Abramova Elena , Zhou Peihong , Joseph Laurie B , Laskin Jeffrey D , Gow Andrew J , Laskin Debra L 
Published: May 2024

Abstract
Recent studies have identified exposure to environmental levels of ozone as a risk factor for the development of acute respiratory distress syndrome (ARDS), a severe form of acute lung injury (ALI) that can develop in humans with sepsis. The aim of this study was to develop a murine model of ALI to mechanistically explore the impact of ozone exposure on ARDS development. Mice were exposed to ozone (0.8 ppm, 3 h) or air control followed 24 h later by intravenous administration of 3 mg/kg lipopolysaccharide (LPS) or PBS. Exposure of mice to ozone + LPS caused alveolar hyperplasia; increased BAL levels of albumin, IgM, phospholipids, and proinflammatory mediators including surfactant protein D and soluble receptor for advanced glycation end products were also detected in BAL, along with markers of oxidative and nitrosative stress. Administration of ozone + LPS resulted in an increase in neutrophils and anti-inflammatory macrophages in the lung, with no effects on proinflammatory macrophages. Conversely, the numbers of resident alveolar macrophages decreased after ozone + LPS; however, expression of Nos2, Arg1, Cxcl1, Cxcl2, Ccl2 by these cells increased, indicating that they are activated. These findings demonstrate that ozone sensitizes the lung to respond to endotoxin, resulting in ALI, oxidative stress, and exacerbated pulmonary inflammation, and provide support for the epidemiologic association between ozone exposure and ARDS incidence.
Combat-related Wartenberg Syndrome Due to Penetrating Shrapnel Injury: A Case Report
Authors: Berger Ori , Lomeli Bernardo A. , Andrakhanov Andrey , Talisman Ran 
Published: May 2024

Summary:
Wartenberg syndrome, also known as Cheiralgia paresthetica, is an uncommon neuropathy affecting the superficial branch of the radial nerve. Typically caused by external compression, it manifests as paresthesia or pain in the radial side of the hand. We present a case of Wartenberg syndrome resulting from combat shrapnel injury, illustrating an uncommon etiology. A 21-year-old soldier was presented with allodynia and paresthesia after a shrapnel explosion, with positive clinical findings and radiographic evidence supporting the diagnosis. Nonoperative management led to significant improvement, highlighting the importance of conservative treatment in such cases. This report underscores the significance of considering unconventional causes in nerve entrapment syndromes post combat trauma, emphasizing adherence to established therapeutic guidelines.
Hippocampal volume mediates the association of arterial stiffness with cognitive impairment in adult population
Authors: Li Xiaoshuai , Xing Jie , Hui Ying , Shi Huijing , Li Rui , Zhang Shun , Chen Shuohua , Li Jing , Liang Xiaoliang , Wu Yuntao , Zhao Pengfei , Wu Shouling , Wang Zhenchang 
Published: May 2024

Objectives:
To investigate the association of arterial stiffness with brain perfusion, brain tissue volume and cognitive impairment in the general adult population.

Materials and methods:
This prospective study included 1488 adult participants (age range: 22.8–83.9 years) from the Kailuan study. All participants underwent brachial–ankle pulse wave velocity (PWV) measurement, brain MRI, and Montreal Cognitive Assessment (MoCA). The association of PWV with cerebral blood flow (CBF), brain tissue volume and MoCA score was investigated. Mediation analysis was used to determine whether CBF and brain tissue volume changes mediated the associations between PWV and MoCA score.

Results:
A 1 standard deviation (SD) increase in PWV was associated with lower total brain CBF [β (95% CI) −0.67 (−1.2 to −0.14)], total gray matter CBF [β (95% CI) −0.7 [−1.27 to −0.13)], frontal lobe CBF [β (95% CI) −0.59 (−1.17 to −0.01)], parietal lobe CBF [β (95% CI) −0.8 (−1.43 to −0.18)], and temporal lobe CBF [β (95% CI) −0.68 (−1.24 to −0.12)]. Negative associations were found for PWV and total brain volume [β (95% CI) −4.8 (−7.61 to −1.99)] and hippocampus volume [β (95% CI) −0.08 (−0.13 to −0.04)]. A 1 SD increase PWV was significantly associated with elevated odds of developing cognitive impairment [odds ratio (95% CI) 1.21 (1.01–1.45)]. Mediation analysis showed that hippocampal volume partially mediated the negative association between PWV and MoCA scores (proportion: 14.173%).

Conclusion:
High arterial stiffness was associated with decreased total and regional CBF, brain tissue volume, and cognitive impairment. Hippocampal volume partially mediated the effects of arterial stiffness on cognitive impairment.