bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Multicomponent Cycloaddition Approaches in the Catalytic Asymmetric Synthesis of Alkaloid Targets
Authors: Perreult Stephane , Rovis Tomislav 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Chiral Biaryl Natural Products by Asymmetric Biaryl Coupling
Authors: Kozlowski Marisa C. , Morgan Barbara J. , Linton Elizabeth C. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diaryliodonium Salts: A Journey from Obscurity to Fame
Authors: Merritt Eleanor A. , Olofsson Berit 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Calixarene‐Based Anionic Receptors
Authors: Shokova E. A. , Kovalev V. V. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biomimetic Design and Performance of Polymerizable Lipids
Authors: Cashion Matthew P. , Long Timothy E. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐ and Copper‐Catalyzed Arylation of Carbon—Hydrogen Bonds
Authors: Daugulis Olafs , Do Hien‐Quang , Shabashov Dmitry 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cyclacenes: Hoop‐Shaped Systems Composed of Conjugated Rings
Authors: Gleiter Rolf , Esser Birgit , Kornmayer Stefan C. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Progress in Asymmetric Bifunctional Catalysis Using Multimetallic Systems
Authors: Shibasaki Masakatsu , Kanai Motomu , Matsunaga Shigeki , Kumagai Naoya 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Utilization of N—X Bonds in the Synthesis of N‐Heterocycles
Authors: Minakata Satoshi 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phosphole‐Containing Calixpyrroles, Calixphyrins, and Porphyrins: Synthesis and Coordination Chemistry
Authors: Matano Yoshihiro , Imahori Hiroshi 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Comparison Among Assisted Synthetic Methodologies for the Preparation of Antitumoral Compounds
Authors: Taddei Maurizio 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleotides and Nucleic Acids — Oligo‐ and Polynucleotides
Authors: Loakes David 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Mean Field Theory of Spin Glasses: The Heuristic Replica Approach and Recent Rigorous Results
Authors: Parisi Giorgio 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Departures in the Synthesis of Peptides and Glycopeptides
Authors: Kan Cindy , Danishefsky Samuel J. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regulation of Gene Expression by Jasmonate Hormones
Authors: Memelink Johan 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Wound Hormone Jasmonate
Authors: Koo Abraham J. K. , Howe Gregg A. 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Methyl Jasmonate: A Plant Stress Hormone as an Anticancer Drug
Authors: Cohen Sharon , Flescher Eliezer 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metal Nanoparticles Supported on Carbon Nanofibers: Synthesis and Application for the Hydrogenation Reactions
Authors: Motoyama Yukihiro , Yoon Seong‐Ho , Nagashima Hideo 
Published: January 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Whiteness, chromaticness, and blackness symmetries for CIELAB, with a numerical example
Authors: Adams Louis W. 
Published: January 2010

AbstractWhiteness, chromaticness, and blackness are defined for CIELAB. These NCS‐like color attributes offer an alternative to lightness and chroma for describing color. Their hue‐preserving symmetries are derived for tristimulus color space. A numerical example provides what theory predicts are visually uniform sequences of colors with constant lightness, whiteness, chromaticness, or blackness. Numerical approximation is unnecessary. Such sets of symmetric colors in one hue are visually interesting, and useful for computer aided design. The appropriateness of such attributes for CIELAB is briefly discussed. © 2010 Wiley Periodicals, Inc. Col Res Appl, 2010
The architectural colour design process: An evaluation of sequential media via semantic ratings
Authors: Ural Sibel Ertez , Yilmazer Semiha 
Published: January 2010

AbstractIn recent studies, contextual situations of applied colours are compared to colours presented as samples or chips. Findings of such studies point out different results in terms of similarities or differences between the evaluations of isolated/abstract colours and contextualized situations. Architectural and spatial contexts have their own characteristics regarding colouring criteria, so it is of great importance to examine the architectural/spatial colouring process from this point of view. This study explores this process by investigating the consistency of semantic ratings of four sequential stages of the architectural colour design process, namely, colour chips/samples, abstract compositions, perspective drawings and 3D models. The architectural context for the study was a simple interior space. Fifteen different colour schemes were applied on the four media representing the stages. Subjects rated the 15 sets against seven bipolar, five‐step semantic differential scales. The scales consisted of harmonious‐discord, pleasant‐unpleasant, comfortable‐uncomfortable, spacious‐confined, static‐dynamic, exciting‐calming and extroverted‐introverted. Findings indicated that there are significant associations between the evaluations of the abstract compositions, the perspective drawings and the 3D models; however, the evaluations of colour chips are significantly different than the others. The medium effect observed mostly between abstract and contextualized media. Additionally, factor analysis showed that pleasantness, harmony, spaciousness and comfort are connected in the evaluations of contextual situations, while pleasantness and harmony differ from spaciousness and comfort in the evaluations of colour chips and abstract compositions. The factor of activity (arousal) (dynamism, excitement, and extroversion) stays the same for all four media. It is also found that different colour characteristics are determinative over different media. © 2010 Wiley Periodicals, Inc. Col Res Appl, 2010
Adaptive structured parallelism for distributed heterogeneous architectures: a methodological approach with pipelines and farms
Authors: González‐Vélez Horacio , Cole Murray 
Published: January 2010

AbstractAlgorithmic skeletons abstract commonly used patterns of parallel computation, communication, and interaction. Based on the algorithmic skeleton concept, structured parallelism provides a high‐level parallel programming technique that allows the conceptual description of parallel programs while fostering platform independence and algorithm abstraction. This work presents a methodology to improve skeletal parallel programming in heterogeneous distributed systems by introducing adaptivity through resource awareness. As we hypothesise that a skeletal program should be able to adapt to the dynamic resource conditions over time using its structural forecasting information, we have developed adaptive structured parallelism (ASPARA). ASPARA is a generic methodology to incorporate structural information at compilation into a parallel program, which will help it to adapt at execution. ASPARA comprises four phases: programming, compilation, calibration, and execution. We illustrate the feasibility of this approach and its associated performance improvements using independent case studies based on two algorithmic skeletons—the task farm and the pipeline—evaluated in a non‐dedicated heterogeneous multi‐cluster system. Copyright © 2010 John Wiley & Sons, Ltd.
Melting of Crystals in Two Dimensions
Authors: Gasser Urs , Eisenmann Christoph , Maret Georg , Keim Peter 
Published: January 2010

AbstractWhile the melting of crystals is in general not understood in detail on a microscopic scale, there is a microscopic theory for a class of two‐dimensional crystals, which is based on the formation and unbinding of topological defects. Herein, we review experimental work on a colloidal two‐dimensional model system with tunable interactions that has given the first conclusive evidence for the validity of this theory on a microscopic level. Furthermore, we show how the mechanism of melting depends on the particle interaction and that a strong anisotropy of the interaction leads to a changed melting scenario.
Ab Initio Molecular Dynamics Simulations of the Adsorption of H2 on Palladium Surfaces
Authors: Groß Axel 
Published: January 2010

AbstractThe interaction of hydrogen with palladium surfaces represents a model system for the study of the adsorption and absorption at metal surfaces. Theoretical gas–surface dynamics studies have usually concentrated on the adsorption dynamics on clean surfaces. Only recently has it become possible, based on advances in electronic structure codes and improvements in computer power, to address the much more complex problem of the adsorption dynamics on precovered surfaces. Herein, recent ab initio molecular dynamics studies are discussed that address the adsorption dynamics of hydrogen molecules on hydrogen‐ and sulfur‐precovered Pd surfaces. In addition, the relaxation dynamics of the hydrogen atoms after the dissociation on clean Pd(100) are presented.
Evaluation of a 12‐color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans
Authors: Autissier Patrick , Soulas Caroline , Burdo Tricia H. , Williams Kenneth C. 
Published: January 2010

AbstractMonitoring changes in human immune cell populations such as lymphocytes, monocytes, and dendritic cells (DCs) during infectious diseases like human immunodeficiency virus (HIV) is crucial. However, difficulties to identify rare or heterogeneous cell populations can be limiting. For example, to accurately measure DC subsets, eight flow cytometry parameters are ideal. The aim of this work was to analyze the phenotype of human lymphocyte, monocyte, and DC subsets using a single 12‐color flow cytometry panel. After erythrocyte lysis, blood from healthy human volunteers was washed and labeled with a cocktail of 12 antibodies. Samples were analyzed on a Becton‐Dickinson FACSAria™ equipped with three lasers. Data were compared with lineage‐specific panels using 5–8 Ab combinations per lineage. Acquired data were analyzed using FlowJo software. Our 12‐color panel allows for the identification of the following major subsets of circulating cells in a single tube: CD4+ and CD8+ T lymphocytes, B lymphocytes, NK cells, NKT cells, monocyte subsets (CD14 and/or CD16), and five nonoverlapping HLA‐DR+Lin− subsets: CD34+ hematopoietic stem cells, CD123+ plasmacytoid DC, and three subsets of CD11c+ myeloid DC expressing either CD16, CD1c (BDCA‐1), or CD141 (BDCA‐3). We have developed a single flow cytometry panel that allows for simultaneous detection of the lymphocyte and monocyte cell populations and all known DC subsets. Studying these major players of the immune system in one single panel may give us a broader view of the immune response during HIV infection and the ability to better define the role of individual cell types in Acquired Immune Deficiency Syndrome (AIDS) pathogenesis. © 2010 International Society for Advancement of Cytometry
Setting the eating disorder aside: An alternative model of care
Authors: Williams Kim D. , Dobney Tracey , Geller Josie 
Published: January 2010

AbstractEating disorder treatment typically involves psychotherapy, structured programmes to normalize eating behaviours, and weight restoration. Unfortunately some individuals who receive these treatments do not recover. The Community Outreach Partnership Program (COPP) was developed to address the needs of these individuals. Using a team approach which combines both community and hospital services, COPP assists clients increase their quality of life by fostering independence, increasing hope and enhancing social skills in the context of the client's economic, social and physical living environment. Preliminary outcome research reveals significant improvement in eating disorder and psychiatric symptoms in individuals who complete four or more months of COPP. Copyright © 2010 John Wiley & Sons, Ltd and Eating Disorders Association.
Blood leukocyte DNA hypomethylation and gastric cancer risk in a high‐risk Polish population
Authors: Hou Lifang , Wang Hao , Sartori Samantha , Gawron Andrew , Lissowska Jolanta , Bollati Valentina , Tarantini Letizia , Zhang Fang Fang , Zatonski Witold , Chow Wong‐Ho , Baccarelli Andrea 
Published: January 2010

AbstractGlobal hypomethylation has been shown to increase genome instability potentially leading to increased cancer risk. We determined whether global methylation in blood leukocyte DNA was associated with gastric cancer in a population‐based study on 302 gastric cancer cases and 421 age‐ and sex‐matched controls in Warsaw, Poland, between 1994 and 1996. Using PCR‐pyrosequencing, we analyzed methylation levels of Alu and LINE‐1, 2 CG‐rich repetitive elements, to measure global methylation levels. Gastric cancer risk was highest among those with lowest level of methylation in either Alu (OR = 1.3, 95% CI = 0.9–1.9) or LINE‐1 (OR = 1.4, 95% CI = 0.9–2.0) relative to those with the highest levels, although the trends were not statistically significant. For Alu, the association was stronger among those aged 70 or older (OR = 2.6, 95% CI = 1.3–5.5, p for interaction = 0.02). We did not observe meaningful differences in the associations by other risk factors and polymorphisms examined. For LINE‐1, the association tended to be stronger among individuals with a family history of cancer (OR = 3.1, 95% CI = 1.4–7.0, p for interaction = 0.01), current alcohol drinkers (OR = 1.9, 95% CI = 1.0–3.6, p for interaction = 0.05), current smokers (OR = 2.3, 95% CI = 1.1–4.6, p for interaction = 0.02), those who rarely or never consumed fruit (OR = 3.1, 95% CI = 1.2–8.1, p for interaction = 0.03), CC carriers for the MTRR Ex5+123C>T polymorphism (OR = 2.3, 95% CI = 1.2–4.4, p for interaction = 0.01) and TT carriers for the MTRR Ex15+572T>C polymorphism (OR = 1.7, 95% CI = 1.0–2.8, p for interaction = 0.06). The association was not different by sex, Helicobacter pylori infection, intake of folate, vitamin B6 and total protein and the remaining polymorphisms examined. Our results indicate that interactions between blood leukocyte DNA hypomethylation and host characteristics may determine gastric cancer risk.
Regulation of HER expression and transactivation in human prostate cancer cells by a targeted cytotoxic bombesin analog (AN‐215) and a bombesin antagonist (RC‐3095)
Authors: Sotomayor Sandra , Muñoz‐Moreno Laura , Carmena María J. , Schally Andrew V. , Sánchez‐Chapado Manuel , Prieto Juan C. , Bajo Ana M. 
Published: January 2010

AbstractBombesin (BN) and gastrin‐releasing peptide (GRP) have been shown to stimulate the growth of human prostate cancer in vivo and in vitro by mechanisms initiated by binding of the peptide to BN/GRP receptor (GRPR). GRPR is overexpressed in a variety of human cancers, including human prostatic carcinoma. This led us to evaluate the effectiveness of blocking GRPR and of chemotherapy targeted to GRPR in androgen‐dependent (LNCaP) and androgen‐independent (PC‐3) prostate cancer cells, which exhibit different features of disease progression. Thus, we used a cytotoxic BN/GRP analog, AN‐215, consisting of 2‐pyrrolinodoxorubicin (AN‐201) linked to BN‐like carrier peptide, and a BN/GRP receptor antagonist, RC‐3095. Semiquantitative RT‐PCR and Western blotting revealed that mRNA and protein levels for GRPR increased in prostate cancer cells as compared with nonneoplastic RWPE‐1 cells. Immunofluorocytochemistry and Western blot assays revealed that AN‐215 was the most effective analog decreasing both the expression of epidermal growth factor receptor family members and the activation of epidermal growth factor receptor and HER‐2, which are associated to a poor prognosis. Furthermore, analogs targeted to BN/GRP receptors, AN‐215 and RC‐3095, blocked the effect of BN on cell growth in RWPE‐1, LNCaP and PC‐3 cells. These findings shed light on the mechanisms of action of these analogs and support the view that the use of AN‐215 and RC‐3095 for blocking BN/GRP receptors for targeted therapy may be of benefit for treatment of advanced prostate cancer.
Insulin‐like growth factor 1 expression correlates with clinical outcome in K‐RAS wild type colorectal cancer patients treated with cetuximab and irinotecan
Authors: Scartozzi Mario , Mandolesi Alessandra , Giampieri Riccardo , Pierantoni Chiara , Loupakis Fotios , Zaniboni Alberto , Galizia Eva , Giustini Lucio , Silva Rosa Rita , Bisonni Renato , Berardi Rossana , Biagetti Simona , Menzo Stefano , Falcone Alfredo , Bearzi Italo , Cascinu Stefano 
Published: January 2010

AbstractSeventy to 40% of K‐RAS wild type colorectal tumors does not seem to benefit from treatment with antiepidermal growth factor receptor (anti‐EGFR) monoclonal antibodies. Recent data suggested that in presence of IGF‐1 system, altered activation colorectal cancer cells may escape anti‐EGFR mediated cell death. The interaction between IGF‐1 expression and K‐RAS mutational analysis was tested to verify the ability of IGF‐1 to identify a subgroup of patients more likely to benefit from EGFR‐targeted antibodies treatment. IGF‐1 expression and K‐RAS mutational status was assessed in advanced colorectal cancer patients receiving irinotecan/cetuximab. One hundred twelve patients were analyzed. IGF‐1 was negative in 30 patients (27%) and overexpressed in the remaining 82 cases (73%). In IGF‐1 negative and IGF‐1 positive tumors, we observed progressive disease in 9 (30%) and 55 (67%) patients, respectively (p = 0.001). Median progression‐free survival was 7.5 mo in patients showing IGF‐1 negative tumors and 3 mo for IGF‐1 expressing tumors (p = 0.002). Among K‐RAS wild type patients, IGF‐1 negative and positive tumors showed a partial response to cetuximab‐irinotecan in 13 (65%) and 11 (22%) cases, respectively (p = 0.002). Median progression‐free survival in IGF‐1 negative tumors was 10 mo and 3.2 mo in IGF‐1 positive colorectal cancers (p = 0.02). IGF‐1 proved to be a possible predictive factor for resistance to anti‐EGFR monoclonal antibodies in K‐RAS wild type colorectal cancer. Combined IGF‐1 and K‐RAS analysis may represent an effective strategy for a better selection of responding colorectal cancer patients.