bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pancreatic cancer with multiple liver metastasis complicating multi organ infarcts from Marantic endocarditis and Trousseau’s syndrome
Authors: Rahman Mir , Wiles Alan , Shekhar Raj 
Published: May 2024

Background:
Marantic endocarditis and Trousseau’s syndrome are historically linked with pancreatic cancer. The patient had catastrophic embolic events which caused multi organ infarct due to underlying advanced pancreatic cancer. Doctors should be aware of early signs and symptoms of pancreatic cancer and conduct necessary clinical assessments and investigations that can prevent any severe complications.

Case Presentation:
A middle-aged healthy gentleman who presented with left-sided weakness, slurred speech, left-sided sensory neglect, mild headache, and fever. CT head showed acute right-sided temporal ischemic changes with subsequent magnetic resonance imaging (MRI) head showed multiple infarcts in the brain. A transesophageal echocardiogram reported possible MV vegetation. MRI of the liver was done due to deranged LFTs which showed multiple liver metastasis with a primary mass in the tail of the pancreas. Left leg ultrasound Doppler showed a large left leg deep vein thrombosis involving the femoral vein as he complained of left leg pain for 2 months and went to GP with right leg pain 3 months ago which was treated as a right ankle sprain. The clinical events explained that most likely he developed Trousseau’s syndrome 3 months ago and the embolic phenomena were due to rare Marantic endocarditis (Non-bacterial thrombotic endocarditis) secondary to pancreatic cancer. Ultrasound-guided biopsy of liver metastasis was planned, but sadly the patient passed away the next day.

Conclusion:
The diagnosis of early pancreatic cancer with imaging poses a challenge sometimes, therefore the pancreatic protocol of CT or MRI is the first line of investigation. Moreover, the cause of unprovoked thrombo-embolism should be investigated to rule out any underlying malignancy.
Tuberculosis-induced osteomyelitis of the right distal tibia in a healthy male Saudi infant: a case report
Authors: Aldrwesh Abdulaziz , Badahdah Abdullah , Albaiji Dalal 
Published: May 2024

Background:
Tuberculosis (TB) is a challenging disease; however, it is preventable and curable in most cases. In 2022, TB was the second most common single infection leading to death worldwide after coronavirus disease. Almost 10 million people get infected with TB every year. TB manifests clinically in two types: pulmonary and extrapulmonary; the pulmonary type is the most common.

Case presentation:
A 17-month-old medically free male infant was referred to our institution with right distal leg pain, swelling and skin changes, started 1 month ago. Since then, both pain and swelling worsened and led to limping. The father denied any history of recent trauma, fever, cough, night sweating, infections, contact with sick patients, skin rashes in other body parts, or any other systematic changes. The baby was delivered at full term by cesarian-section due to placenta previa, with a birth weight of 3500 g, Prenatal and postnatal history is unremarkable. The patient was vitally stable and appeared healthy with no dysmorphic features. He was able to bear weight on his feet; however, his gait and walking abilities could not be assessed. Local examination showed swelling, erythema, and tenderness over the right distal tibia with an intact range of motion. The patient was admitted and initial investigations were done for him. After close observation and multiple investigations, a diagnosis of TB-induced right tibial osteomyelitis was made, and first-line management was initiated.

Conclusion:
This report highlights the importance of orthopedic surgeons in considering TB-induced osteomyelitis in the differential diagnosis of vague musculoskeletal symptoms.
Synthesis, <i>In-vivo</i> estimation of Novel 3-(6-Substituted Benzthiazole-2-yl /Oxadiazole-2-yl)-2-Substituted 4-Quinazolineones
Authors: Rishipathak Dinesh D. , Thombare Yogita B. , Gupta Ashutosh R. , Shinde Kanchan S. , Jain Bhagyashri P. , Ghodke Shantanu S. 
Published: May 2024

Even with all of the new and old therapies available, seizure management is infamously difficult. Scientists will continue to search for novel drugs with high selectivity and low central nervous system side effects in the hopes of finding the newest and most effective treatment. This work designates the synthesis of several 4- quinazolinones substituted with oxadiazoles and benzothiazoles through condensation of 2-substituted-4H-benzo(1,3)-oxazin-4-ones with substituted-oxadiazole and 6-substituted-benzothiazol-2-amine. The title compounds were confirmed through IR, 1H-NMR, 13C-NMR analyses. The compounds evaluated for anticonvulsant activity. Compounds A3, A4, A9, A5, A10 possess good potential. They reduce the extent of tonic phase up to 1.3 to 1.1 seconds and stupor up to 100 to 51 seconds with absence of straub phase when compared to the control group.
عــلم البديـــع في صفــوة التفاســـــير
Authors: إبراهيم محمد خليل , سلطان ضرغام بشير 
Published: May 2024

إن القرآن الكريم المعجزة الباقية إلى يوم الدين ، والحجة الدائمة على الخلق ، والنبراس للعلماء والدعاة ، فهو كتاب إرشاد وعناية وتشريع وهداية ، وإعجازه متعدد الوجوه من حيث فصاحته وبلاغته ونظمـه وتراكيبه وأساليبه ، وما تضمنه من أخبار ماضية ومستقبلية ، ومااشتمل عليه من أحكام جليـة ، وهو لا تنقضي عجائبه ولا تنقطع فوائده ، ومن أعظم وجوه إعجازه الإعجاز البياني ، لأننا نجده في كلماته ، وفي كل آية من آياته .
وقد كان لاختيارنا هذا الموضوع أسبابه ، من أهمها : أن الموضوع يستحق الدراسة ، لأن كتاب صفوة التفاسير يعد كنزاً من الكنوز العلمية الثمينة ، إذ إنه كتاب جامع شامل لعلوم اللغـة العربية ، فهو فضـلاً عن شرحه للآيـات الكريمات فإننا نجد فيه الفقـه ، واللغـة ، والنحو ، والصرف ، والبلاغة ، مما جعل هذا الكتاب جديراً بأن يحظى بالاهتمام والدراسة ، ولاسيما أنّ البلاغة أخذت حيزاً واسعاً فيه ، لذا آثرنا الكشف عن إمكانية الصابوني في فهمه للبلاغة ، وبخاصة فنون علم البديع ، وكيفية تحليله البلاغي للنصوص القرآنية الكريمة .
وقد تناولـنا الموضوع على وفق خطة تقوم على مبحثين وخاتمة.
أما المبحثان فتناول الأول منهما المحسنات المعنوية ، والثاني المحسنات اللفظيـة ، ثـم ختمنا البحث بخاتمة ضمت أهم النتائج التي توصلنا إليها.
ثورات الأندلسيين بعد تسليم مدينة غرناطة دراسة تاريخية للأسباب والنتائج
Authors: عناد وجدان فريق 
Published: May 2024

الكتابة عن الأندلس بعد تسليم مدينة غرناطة يحمل في ثناياه ألم كبير، لأن الأندلسيين عاشوا تجربة إنسانية قاسية سببها الأساس غياب التسامح الديني والعدالة الاجتماعية، الأمر الذي دفعهم للثورة مطالبين بحقوقهم التي نصت عليها معاهدة تسليم المدينة. فقد عاش أولئك حياة صعبة ، فكانوا صورة للصراع بين حضارتين الإسلامية والغربية ، ويمكن تلمس ذلك الصراع من خلال دراسة ثوراتهم ضد السلطة الحاكمة التي يبدو من تتبع أحداثها بشكل واضح اسباب اندلاعها فضلا عن نتائجها. والباحث في تاريخ تلك المدة الزمنية لابد ان يعترف ان السلطة الحاكمة في اسبانيا كانت تسعى إلى الابادة الجماعية للأندلسيين
أثر المنحى البنائي في تحصيل طلاب الصف الثاني المتوسط في مادة الاجتماعيات وتنمية تفكيرهم عال الرتبة
Authors: خميس الدليمي طارق هاشم , عبدالله خلف العجيلي اسعد حمود 
Published: May 2024

يهدف البحث الحالي التعرف على (أثر المنحى البنائي في تحصيل طلاب الصف الثاني المتوسط في مادة الاجتماعيات وتنمية تفكيرهم عالي الرتبة).
ولغرض التحقق من ذلك تم فرض الفرضيات الآتية:
الفرضية الرئيسية الأولى:
الفرضية الرئيسة الأولى : لا يوجد فرق ذو دلالة احصائية بين متوسط درجات طلاب المجموعة التجريبية الاولى الذين يدرسون مادة الاجتماعيات باستعمال أنموذج (المنحى البنائي) ومتوسط درجات المجموعة الضابطة الثانية الذين يدرسون باستعمال (الطريقة الاعتيادية) في اختبار التحصيل .
الفرضية الرئيسية الثانية:
لا يوجد فرق ذو دلالة احصائية بين متوسط درجات طلاب المجموعة التجريبية الذين يدرسون مادة الاجتماعيات باستعمال أنموذج (المنحى البنائي) ومتوسط درجات طلاب المجموعة الضابطة الذين يدرسون باستعمال (الطريقة الاعتيادية) في اختبار التفكير عالي الرتبة.
استعمل الباحثان المنهج التجريبي واختار التصميم التجريبي ذا المجموعات المتكافئة ذات الاختبار القبلي والبعدي، تألف مجتمع الدراسة من طلاب الصف الثاني المتوسط في المدارس المتوسطة التابعة للمديرية العامة لتربية محافظة صلاح الدين/ تكريت/ البوعجيل للعام الدراسي (2018-2019) لغرض تطبيق التجربة، بلغت عينة الدراسة (65) طالباً من طلاب الصف الثاني المتوسط وزعوا على مجموعتين تجريبية و ضابطة، حيث كان عدد المجموعة التجريبية (22) طالبا الذين درسوا وفق إنموذج المنحى البنائي وعدد المجموعة الضابطة (23) طالبا الذين درسوا وفق الطريقة الاعتيادية وقد توصل الباحثان الى النتائج الآتية :

تفوق طلاب المجموعة التجريبية التي درست المادة بوساطة إنموذج (المنحى البنائي) على المجموعة الضابطة الذين درسوا مادة الاجتماعيات باستعمال (الطريقة الاعتيادية) في اختبار التحصيل لمادة الاجتماعيات .
تفوق طلاب المجموعة التجريبية الذين درسوا مادة الاجتماعيات باستعمال إنموذج (المنحى البنائي) على زملائهم في المجموعة الضابطة الذين درسوا بالطريقة الاعتيادية في اختبار التفكير عال الرتبة .
The Role of Prosodic Features in Conversational Interaction : Hard Talk a Case Study
Authors: Ali Hadeel Kamil , Fouad Ameena Farouk 
Published: May 2024

This study aims to look into the relationships between prosodic features from phonological perspective and interactional relationships and sequence organization from conversation analysis (CA) view. There are specific prosodic cues that speakers employ to signal to one another when it is their turn to talk in any speech situation. These cues serve as signs to let other people know when it is the speaker's turn to talk. It is important to demonstrate that some prosodic patterns indicate the end or continuation of a turn. Prosodic orientation, such as intonation and tone patterns, are hypothesized to reveal information about participants' matching and non-matching of a prior turn. The consistent use of the same pitch height indicates that there is agreement among the participants on a specific situation. PRAAT, a computer program is used for doing acoustic analysis to conduct the prosodic analysis following Ladefoged’s model. It is supposed that when the speaker makes a low pitch, he is no more interested in the topic raised or no more excited, but when there is a high pitch that means there is more to be added and some significant issues can be shown However, prosodic orientation is obviously used in political interviews in a manner similar to that of ordinary speech. As well as Political interviews commonly employ pauses, interrupted speech, and reasoning, some of which show a particular orientation to the preceding turns
Formulation, Evaluation, and Characterization of Indapamide Niosomes
Authors: B Archana , Yallapragada Sahithi Sri Charani , Pawar Sony , D Sathvika , Gotham Sathwika 
Published: May 2024

Niosomes, also known as nonionic surfactant vesicles, are one of the many carriers used to carry drug molecules to their target sites. They can hold both hydrophilic and hydrophobic medicines. Indapamide is an angiotensin II type 1 receptor (AT1) antagonist medication primarily used to treat high blood pressure. Niosomes containing Indapamide were created utilizing the thin film hydration process with various cholesterol concentrations and nonionic surfactants (span 60). All noisome formulations were assessed for entrapment efficiency, drug content, reproducibility, vesicular diameter, shape and size distribution microphotography, FTIR analysis, and in vitro release experiments. The results indicate that in all of the created niosomal formulations, as the surfactant content increases, the entrapment efficiency also increases. The drug content ranged between 90.06±0.57 and 96.15±0.42, with a low standard deviation. Niosomes range in size from 0.280±0.098µm to 0.299±0.044µm and have a spherical shape. The IR spectrum analysis indicated no interaction between the medication and the formulation ingredients. Membrane diffusion cells were used to study the in vitro dissolution parameters. The results demonstrate that formulation F6 had a better-controlled release action than other formulations, with an 'n' value of 0.917, indicating that the medication was released using zero-order kinetics.
ANXIETY AND DEFENESE MECHANISMS PORTRAYED IN “CAT ON A HOT TIN ROOF”
Authors: Afandi Mujad Didien , Muflihah Tatik , Aquariza Novi Rahmania 
Published: May 2024

Born and raised in a poor family, a childless woman named Margaret who is a wife of an alcoholic, has an ambition for wealth which eventually causes her to live with anxiety. To suppress the anxiety, she uses defense mechanisms. Therefore, this study was conducted to analyze the anxiety and defense mechanisms portrayed through Margaret in the drama, entitled “Cat on a Hot Tin Roof”. This qualitative study analyzed the anxiety and defense mechanisms portrayed in one of the canonical drama of Tennessee Williams using psychological lens. The data describing Margaret's anxiety and defense mechanisms collected from this drama were revealed and interpreted descriptively in order to provide detailed explanation and deep understanding. This study identified that the anxiety experienced by Margaret was resulted from her ambition to inherit the wealth of her father-in-law. Poverty in her past life has led her to become ambitious to pursue her dreams of wealth. Besides, she got anxious about her inability to give a child to her husband. In consequence, her childlessness caused her to have anxiety. To cope with the anxiety, she used three types of defense mechanisms: (1) reaction formation, (2) displacement, and (3) denial. The female major character experiences anxiety about wealth and childlessness. To protect herself from the anxiety, she uses reaction formation, displacement, and denial as defense mechanisms.
METACOGNITIVE STRATEGY IN READING COMPREHENSION USED BY THE STUDENTS OF STKIP YAYASAN ABDI PENDIDIKAN PAYAKUMBUH
Authors: Hervina Hervina , Nifriza Ifna , Afdaleni Afdaleni , Thampisa Dila 
Published: May 2024

This study is descriptive qualitative. The sample of this study was sixth semester students in English department of STKIP Abdi Pendidikan Payakumbuh. There were 31 students. The writer choose the sample by using purposive sampling technique. The instrument of this study was the questionnaire which was consist of 30 items based on survey of reading strategy developed by Mokhtary and Sheorey in 2002. Based on data analysis the data can be shown as follow: in using Global Strategy; 8.44% students chose always, 36.22% students chose often, 43.67% students chose sometime, 10.91% students chose seldom and 0.74% students chose never. Meanwhile, in using problem solving Strategy; 12.91% students chose always, 43.15% students chose often, 38.737% students chose sometime, 3.63% students chose seldom and 1.61% students chose never. Last, in using support strategy; 15.43% students chose always, 36.2% students chose often, 35.12% students chose sometime, 11.83% students chose seldom and 1.43% students chose never. Based on the data, it can be concluded that metacognitive strategy in reading comprehension applied by the students were Support strategy and then followed by Problem – solving strategy and Global strategy.Keywords: metacognitive strategy, reading comprehension, STKIP students
FORMATIVE ASSESSMENT VS SUMMATIVE ASSESSMENT: A CASE STUDY OF ESP LECTURERS IN UNIVERSITY IN INDONESIA AND THAILAND
Authors: Rachmawati Dwita Laksmita , Oktafiah Yufenti , Budiarti Dwi 
Published: May 2024

Providing an assessment and feedbacks are crucial parts for teaching and learning phase as well as for continued growth in the education system. In general, assessing the students’ progress and giving feedbacks as reflections of progress can be done in a variety of ways. The recent research is primarily concerned with how the formative assessment, as the most advantageous and beneficial kind of evaluation can be considered as a sufficient contributor to the instruction process, particularly once followed by genuine constructive feedbacks. This research's findings claimed that the formative assessment and feedbacks have a significant impact on what the learners perform and how the instructors teach. This research explored how formative assessment is implemented in ESP classes, particularly in Business English classes at universities in Indonesia and Thailand.
BILINGUAL INSTRUCTIONS OF INDONESIAN PRIMARY SCHOOLS IN ENDENESE COMMUNITY
Authors: Sama Gratiana , Doi Maksimilianus , Irawati Wanggai Febe Fenny 
Published: May 2024

This study aims at determining the first-grade teacher perception of primary school on the use of bilingual instructions and the impact on students’ learning outcomes. This qualitative study used the first-grade teacher who taught reading and writing in first year students at SDK Pu’ubheto, Ende Sub-district of Ende Regency. The data were collected through in-depth interview, observation and documentation. The interview document data were analyzed descriptively. The result showed that the teacher was successfully implementing bilingual instruction. Finally, the implementation of bilingualism by the teacher affected teacher-student interaction and improved students' reading and writing skill and learning outcomes..
THE EFFECT OF POINT-COUNTERPOINT STRATEGY ON STUDENTS ‘ABILITY IN SPEAKING SKILL AT THE EIGHTH GRADE OF UPTD SMP NEGERI 1 GUNUNGSITOLI IN 2022/2023.
Authors: Gea Donata Deli Bertin , Laoli Adieli , Maru’ao Nursayani , Telaumbanua Kristof Martin E 
Published: May 2024

This research aimed to investigate whether is there a significant effect of Point-Counterpoint Strategy on Students’ ability in Speaking Skill or not. The research was conducted by using Quantitative Research especially in Quasi-Experimental Design. The Population of the research was eighth grade of UPTD SMP Negeri 1 Gunungsitoli that consisted of 287 students. The research took sample which consist of 64 students by using Cluster Sampling Technique. The instrument used in collecting data was Directed Response Task. The instrument of my research is sound record, handphone, and documentation. The test was validated by three validators and it was stated valid. Then the researcher gave the pre-test and post-test to experimental class and control class to find the normality and homogeneity of the sample. After conducting the research, the researcher analyzed the data and the result shows (1) the mean score of students’ ability in pre-test of experimental class was 66,41 and control class was 61.10. (2) The mean score of students’ ability in post-test of experimental class 87,22 and in control class was 70.00. (3) The result of testing hypothesis , the researcher found that tcount was 12.127 and ttable was 1.659. Since tcount(12.127) ttable(1.659), it can be concluded that Ha is accepted. (4) There is a significant effect of Point-Counterpoint Strategy on students’ ability in speaking skill especially in expressing asking and giving opinion at the eighth grade of UPTD SMP Negeri 1 Gunungsitoli in 2022/2023.Furthermore, the researcher has some suggestion related to the research: (1) The English Teacher should use Point-Counterp oint Strategy in teaching Speaking especially in expressing asking and giving opinion material. (2) The English Teacher should be able to guide the students in practicing speaking orally by using expression, dialog, and enhancing the students’ vocabulary. The researcher suggest for the next researcher to use Point-Counterpoint Strategy in the other skill of language.
IMPLEMENTATION OF MULTI-BLENDED LEARNING MODEL IN ENGLISH TEACHING AT THE REMOTE AREA SCHOOL IN BURU-MALUKU
Authors: AR Nirwana. , Pellu Mitha Rahmawati , Hajar Ibnu , Bin Tahir Saidna Zulfiqar 
Published: May 2024

Multi-blended learning model was combination of four learning models. They were independent learning model, face to face learning model, small group learning model, and online learning model. This research employed descriptive qualitative method. The research sample consisted of one teacher and 36 students at SMA Negeri 2 Buru, Maluku. The collected data employed observation and interview, and then the data is presented descriptively. The result study was used to explain the challenges faced by teacher and students’ perception in implementation of Multi-Blended Learning Model in English teaching at the remote area school. The challenges faced in independent learning model were low interest and motivation to learn independently, low control and sufficient attention from parents, low support from parents, and low economic level of students’ parents. The second challenges faced in face to face classroom learning model were limited teaching time, large number of students in one class, and different English ability in one class. Several obstacles found in small group learning model were limited teaching time, and large number of students in one class. The obstacles found in online learning model was that some students did not have internet data package, so they could not update information and new materials optimally. Students’ perception that multi-blended learning model was very helpful for students to collaborate and interact among students and teacher. Students became enthusiastic to learn independently and understanding of teacher’s material well through video tutorial available on the teacher’s YouTube content.
THE IMPACT OF AUDIT COMMITTEE CHARACTERISTICS ON FINANCIAL REPORTING QUALITY: EVIDENCE FROM SAUDI ARABIA
Authors: Alhumoudi Hamad 
Published: May 2024

Purpose: The purpose of this study is to investigate the impact of audit committee characteristics, namely independent members in the audit committee, a financial expert in the audit committee, frequency of meetings, and audit committee size on financial reporting quality proxies by qualified audit opinion, to shed light on the role of audit committee characteristics towards the financial reporting quality with audit quality as one of the control variables, particularly the appointment of Big 4 company.

Design/Methodology/Approach: A sample of 292 observations from Saudi non-financial listed companies from 2019 -2022 were collected from annual reports across four years and analyzed using panel data. To analyze the proposed hypothesis, the study employed multiple linear regression and logistic regression.

Findings: The results indicate that the only audit committee characteristic statistically related to financial reporting quality measured by qualified audit opinion is the financial expert's number. There is also evidence that audit quality measured by audit company size (Big4) is positively related to the audit committee and financial reporting quality.

Research Limitations/Implications: The study’s main limitation is that a large sum of the data collected are traced back to the lockdown period. Therefore, the examined issues could change in the future due to the shift in priorities that the COVID-19 pandemic is determining.

Practical Implications: The result will help accountancy professionals and governments as it highlights the relevance of qualified audit opinions to audit committees and enhances audit committees’ characteristics and role in improving audit quality. The findings of this study contribute to the current audit quality and reporting literature.
Study on the Impact of the Construction of the Sichuan-Tibet Railway on the Food Culture of the Areas Along the Route
Authors: Gao Junxi , Li Jian , Wang Xindan 
Published: May 2024

The construction of the Sichuan-Tibet railway has greatly improved the transportation convenience along the railroad and effectively promoted the rapid development of the regional economy. The Sichuan-Tibet railway is not only an important transportation infrastructure, but also will have an impact on the culture of the areas along the route. This study collects a large amount of data on Tibetan dietary habits and changes in dietary preferences through field investigation and literature collation and analyzes the dietary production methods, ingredient choices, and dietary occasions in Tibetan dietary culture through the data, and finds that Tibetan dietary customs, dietary types, dietary productions, and dietary environments differ greatly from those of the major ethnic groups of Han Chinese. With the opening of the Sichuan Tibet railway and the development of the tourism industry, local residents will face the invasion of foreign cultures. Targeted strategies have been proposed to avoid cultural conflicts and promote diversified regional cultural development.