bluuebunny/crossref_metadata_2025_split huggingface dataset:
Метод оценки подземных территорий города Еревана как объектов двойного назначения
Authors: Манвелян Зара , Микаелян Аракся , Саркисян Лилит 
Published: May 2024

Во многих странах последние десятилетия характеризуются расширением и развитием городов, а также растущим числом природных и техногенных катастроф. В связи с отмеченными тенденциями, актуальной становится задача размещения части городских сооружений различ­ного назначения под землей, а также проектирование и эксплуатация этих объектов в условиях чрезвычайных ситуаций. Целью работы является анализ возможности использования городских подземных территорий г. Еревана в качестве объектов гражданской обороны. В ходе анализа был предложен метод оценки эффективного использования подземных сооружений с помощью эко-экономических параметров и способы доведения их защитных свойств до уровня, соответству­ю­щего требованиям МЧС РА. Выявлена математическая зависимость используемого объема подзем­ного сооружения от количества укрываемых людей и необходимой вентиляции. Материал иссле­дования доказываeт экономическую эффективность использования город­ских подземных терри­торий в качестве объектов двойного назначения.
Predicting Complications in 153 Lumbar Pedicle Subtraction Osteotomies by a Single Surgeon Over a 6-Year Period
Authors: Baker Seth C. , Lucasti Christopher , Graham Benjamin C. , Scott Maxwell M. , Vallee Emily K. , Kowalski David , Patel Dil V. , Hamill Christopher L. 
Published: May 2024

Introduction:
Pedicle subtraction osteotomy (PSO) is a complex surgical procedure that provides correction of moderate sagittal imbalance. Surgical complications have adverse effects on patient outcomes and healthcare costs, making it imperative for clinical researchers to focus on minimizing complications. However, when it comes to risk modeling of PSO surgery, there is currently no consensus on which patient characteristics or measures should be used. This study aimed to describe complications and compare the performance of various sociodemographic characteristics, surgical variables, and established risk indices in predicting postoperative complications, infections, and readmissions after lumbar PSO surgeries.

Methods:
A review was conducted on 191 patients who underwent PSO surgery at a single institution by a single fellowship-trained orthopaedic spine surgeon between January 1, 2018, and December 31, 2021. Demographic, intraoperative, and postoperative data within 30 days, 1 year, and 2 years of the index procedure were evaluated. Descriptive statistics, t-test, chi-squared analysis, and logistic regression models were used.

Results:
Intraoperative complications were significantly associated with coronary artery disease (odds ratios [OR] 3.95, P = 0.03) and operating room time (OR 1.01, P = 0.006). 30-day complications were significantly cardiovascular disease (OR 2.68, P = 0.04) and levels fused (OR 1.10, P = 0.04). 2-year complications were significantly associated with cardiovascular disease (OR 2.85, P = 0.02). 30-day readmissions were significantly associated with sex (4.47, 0.04) and length of hospital stay (χ2 = 0.07, P = 0.04). 2-year readmissions were significantly associated with age (χ2 = 0.50, P = 0.03), hypertension (χ2 = 4.64, P = 0.03), revision surgeries (χ2 = 5.46, P = 0.02), and length of hospital stay (χ2 = 0.07, P = 0.03).

Discussion:
This study found that patients with coronary vascular disease and longer fusions were at higher risk of postoperative complications and patients with notable intraoperative blood loss were at higher risk of postoperative infections. In addition, physicians should closely follow patients with extended postoperative hospital stays, with advanced age, and undergoing revision surgery because these patients were more likely to be readmitted to the hospital.
OS BENEFÍCIOS DE UMA VISITA ESTENDIDA NA UNIDADE DE TERAPIA INTENSIVA (UTI)
Authors: Rodrigues Ana Vanessa Figueira , Silva Ariomar Souza da , Lopes Ingrid de Souza , Oliveira Helena Cristina Loureiro de , Fontes Marinete de Araújo , Lemos Israel Ananias de , Soares Fabiane Veloso 
Published: May 2024

O presente estudo teve como objetivo analisar o impacto na recuperação do paciente com o método de visita estendida. Foi empregada a metodologia da Revisão Integrativa de Literatura, na qual foram utilizados artigos provenientes de fontes renomadas, incluindo o PubMed (National Library of Medicine e National Institutes of Health), SciELO (Scientific Electronic Library Online), IBECS (Índice Bibliográfico Español en Ciencias de la Salud) e o site oficial da FURG (Portal de Periódicos Científicos da Universidade Federal do Rio Grande – FURG). Os resultados estão organizados em três subtítulos que evidenciam os benefícios do método de visita estendida na seção de resultado e discussão, abordando: percepções dos profissionais e familiares quanto a visita estendida, funcionamento e o objetivo da visita estendida e benefícios da visita estendida para a recuperação do paciente. Portanto, ao caminhar para as considerações finais, foi possível compreender que as visitas acabam sendo um momento muito esperado pela família e que apresentam muitos benefícios, pois é nesse momento que aproveitam para sanar as dúvidas, levar acolhimento, demonstrar carinho e afeto e também sentir que está fazendo parte do processo de cuidado do seu ente querido, enquanto para o paciente sentir o cuidado, interagir, ampliar a comunicação e o tempo de contato, demonstra surgir grandes efeitos no seu tratamento, minimizando a ansiedade e o medo.
UNSOLVED ISSUES OF CHEMOTHERAPY OF CHILDHOOD TB
Authors:   Central TB Research Institute, Moscow, Russia,N.I. Pirogov Russian National Research Medical University, Moscow, Russia Submitted as of, Gubkina M.F. , Sterlikova S.S. , Khokhlova Yu.Yu. , Petrakova I.Yu. , Yukhimenko N.V. ,   Central TB Research Institute, Moscow, Russia
Published: May 2024

Тhe current standards of chemotherapy of childhood TB recommend a specific set of drugs for treatment initiation, an optimal consequence of drug replacement, and treatment duration; however, they cannot recommend the most appropriate alternative for a specific patient in a special situation. The articlescribes two clinical cases illustrating individualized approaches to chemotherapy of childhood TB, which cannot be treated using standard chemotherapy regimens due to various reasons; these approaches have resulted in favourable outcomes of the disease. The individualized approach to treatment of a patient co-infected with HIV/TB excluded rifampicin despite preserved sensitivity to first- and second-line drugs and involved continued antiretroviral therapy (ART) without correction. A patient with advanced sputum negative pulmonary TB without risk of developing MDR received additional second-line drugs and a prolonged intensive phase of treatment up to 8 months. In both cases effective treatment results were achieved without surgical interventions.
VERA ARKADYEVNA FIRSOVA – AN UNFINISHED STORY. SCIENTIFIC PROJECTS OF THE CHILDREN AND ADOLESCENTS’ DEPARTMENT FOR PRACTICAL PHTHISIOLOGY
Authors:   Central TB Research Institute, Moscow, Russia, Ovsyankina E.S. , Panova L.V ,   Central TB Research Institute, Moscow, Russia, Gubkina M.F ,   Central TB Research Institute, Moscow, Russia,N.I. Pirogov Russian National Research Medical University, Moscow, Russia
Published: May 2024

Preserving the best clinical traditions passed down by our teachers ensures the quality of scientific research, professional care for children and adolescents with TB, staff training – this makes up the legacy and originality. Years pass, the techniques for diagnosing and treating TB change, new people come, but success follows those who preserve the most important and invaluable – the memory of people who gifted boundless love for the profession, the job they served. When the connection between generations is uninterrupted, every work makes sense. Let’s thank our teachers for the knowledge granted to us. Undoubtedly, every new idea implemented in clinical practice is a credit to our teachers.
PATHOGENETIC THERAPY OF CARDIOVASCULAR DISORDERS IN OLDER CHILDREN AND ADOLESCENTS WITH MDR/XDR PULMONARY TB
Authors:   Central TB Research Institute, Moscow, Russia, Piskunova O.A. , Panova L.V. ,   Central TB Research Institute, Moscow, Russia, Bereznitskaya V.V. ,   Yu.E. Veltishchev Research Clinical Institute of Pediatrics of N.I. Pirogov Russian National Research Medical University,  Moscow, Russia, Shergina E.A. ,   Central TB Research Institute, Moscow, Russia
Published: May 2024

We carried out a cohort retrospective-prospective study in order to evaluate the impact of pathogenetic therapy of cardiovascular disorders (CVD) on bedaquiline (Bq) containing TB treatment in older children and adolescents with multi or extensively drug resistant (MDR/XDR) pulmonary TB. The study included 51 patients aged 13–17 years with pulmonary TB and established MDR/pre-XDR/XDR hospitalized in 2014–2023. The prospective study included 35 patients (main group), and the retrospective study included 16 patients (control group). The main group was administered correction of CVD due to QTc interval prolongation without Bq withdrawal; in the control group Bq was withdrawn (according to the current clinical recommendations). We established conduction disturbances in the form of QTc interval prolongation in both main and control groups, 45.7 and 18.7% respectively. In the control group QTc interval prolongation, which required Bq withdrawal, was observed in 3 out of 16 cases. The analysis of proarrhythmogenic factors and comprehensive ECG monitoring in the main group established functional nature of the changes (slow QTc interval adaptation to heart rate changes) in 16 out of 35 cases. Due to pathogenetic therapy (replacement, metabolic therapy, use of β-adrenoblockers) aimed to mitigate the impact of proarrhythmogenic factors we managed to neutralize signs of electrical instability of the heart and continue Bq containing treatment. The comparison of the frequency of Bq withdrawal between the groups associated with correction due to CVD established a significant correlation between the studied risk factor and the outcome (withdrawal of Bq) (χ2 = 3.997; p < 0.05). Thus, our study demonstrated that timely target correction of modifiable risk factors reduced the probability of drug-induced arrhythmia and allowed safe administration of TB drugs with potential cardiotoxic effect.
Educação Bilíngue no Brasil: estudo a partir de produções acadêmicas sobre o ensino de língua estrangeira para crianças em um contexto multicultural
Authors: Mello Costa de Carvalho Maria Isabel , De Bona Viviane 
Published: May 2024

O objetivo do presente estudo é o de identificar o que as pesquisas que emergem de produções científicas nos últimos dois anos (2021 e 2022) abordam sobre Educação Bilíngue no Brasil e suas implicações no ensino escolar. Por meio de uma pesquisa bibliográfica e com apoio em autores como Antonieta Megale (2018, 2019), Ofélia Garcia (2009, 2011), além da legislação publicada pelo Conselho Nacional de Educação (CNE) acerca das Diretrizes Curriculares Nacionais para a oferta de Educação Plurilíngue (Brasil, 2020), nos debruçamos em 10 pesquisas que deram origem às categorias de análise: “Educação bilíngue: trajetória e singularidades no ensino de língua estrangeira para crianças” e “A prática educacional bilíngue: aspectos da aprendizagem.” Os resultados evidenciaram a prática da educação bilíngue advinda de um mundo globalizado como um instrumento de empoderamento para os seus sujeitos visando o desenvolvimento de habilidades e competências decorrentes de uma prática educacional multicultural alinhada ao ensino de uma língua adicional estrangeira.
English Language Spread and Development in Asian Countries
Authors: Namsraijav Munkhbayar 
Published: May 2024

Within this study we tried to explore spread of English, historical development, implementing policy and future trends in English in Asian countries such as Singapore, Philippine, Khong Kong, Malaysia, Taiwan, Japan and Korea. This will help to determine future trends and English language education role of our country.
Азийн орнуудын англи хэлний тархалт ба хөгжил
Хураангуй: Тус өгүүлэлдээ Сингапур, Филиппин, Хон Конг, Хятад, Малайз, Тайван, Япон, Солонгос зэрэг Азийн орнуудын англи хэлний тархалт ( Качру, 2009) болон түүхэн замнал, англи хэлний сургалтад баримталж буй бодлого, цаашдын чиг хандлага зэргийг дэлгэрэнгүй судалж үзэхийг хичээлээ. Энэ нь өөрийн орны англи хэлний боловсролын үүргийг тодорхойлох, ирээдүйн чиг хандлагыг тогтооход чухал үүрэгтэй билээ.
Түлхүүр үг: Азийн орнуудын англи хэлний хөгжил, бодлогын шинж чанар, боловсролын үүрэг, ирээдүйн чиг хандлага
Thematic Classification of Educationally Significant Phrases
Authors: Shirnen Tsolmon , Ravdanjamts Urgamal , Badrakh Anar 
Published: May 2024

Mongolians have effiently paid attention to their young children's knowledge and education from generation to generation, and in order to properly develop their upbringing, morals, and aesthetics, they have organised educational activities based on phrases and idioms passed down through the people. When we attempted to define such phrases and idioms based on their cognitive and educational relevance, we have considered Mongolian national customs, habits, features and the ways of thinking or mentality.
Сурган хүмүүжүүлэх ач холбогдол бүхий хэлц хэллэгийг сэдэвчлэн ангилах нь
Хураангуй: Аливаа ард түмний сурган хүмүүжүүлэх ухааны үндэс нь ардын аман зохиолын бүх төрөл зүйлд болон тухайн ард түмний дунд үеэс үед уламжлагдан ирсэн хэлц үг хэллэгт тусгалаа олсон байдаг бөгөөд энэ нь өсвөр үеийнхэнд ёс суртахуун, оюун ухаан, хөдөлмөр, гоо үзэсгэлэн, бие бялдрын боловсрол олгох замаар үеийн үед уламжлагдан ирсэн билээ. Бид энэхүү өгүүлэлдээ танин мэдэхүйн болон сурган хүмүүжүүлэх ач холбогдлоор нь хэлц үг хэллэгийг ангилах оролдлого хийсэн ба тэдгээрийг ашиглан сургалтын үйл явцыг үр дүнтэй зохион байгуулах боломжтой гэж үзсэн болно.
Түлхүүр үг: Сургалтын үйл явц, боловсрол, танин мэдэхүй, сэтгэл хөдлөл, хүний үйл ажиллагaa
LITERARY TEXT LINGUISTIC CREATIVITY AND NOVEL MRS. DALLOWAY BY VIRGINIA WOOLF
Authors: Карнюшина В.В. 
Published: May 2024

В статье рассматриваются лингвокреативные аспекты лите-ратурного творчества в целом и некоторые аспекты проявления лингвокреа-тивности в творчестве английской писательницы Вирджинии Вульф, в частно-сти. Автором исследуется понятие «лингвокреативность» и рассматриваются проблемы выявления и исследования лингвокреативности в художественных произведениях. Доказывается, что роман Миссис Деллоуэй является примером лингвокреативного использования автором языковых средств. При этом основ-ными новаторскими приемами в романе определены особый авторский синтак-сический параллелизм и особое выстраивание сюжетной линии. Делается вывод о том, что автор использует новаторский подход в описании социального време-ни, объединения в единое пространство и время героев с использованием ори-гинальных лингвостилистических приемов. Кроме того, автор делает попытку исследовать проблему нелинейного течения времени в художественном тексте, делая проблематику изучения социального времени в литературе и языке акту-альной и требующей дальнейшей разработки.
The article highlights the linguocreative aspects of literary works in general and some aspects of its manifestation in the novel of the English writer Virgin-ia Woolf, in particular. The author examines the problems of identifying and research-ing the notion of linguistic creativity and its manifestation in literary work. It is proved that Mrs. Dalloway is a vivid example of the linguocreative usage of linguistic means and stylistic devices. At the same time, the main innovative techniques in the novel are the author’s unique syntactic parallelism, and an innovative alignment of the storyline. It is concluded that Virginia Woolf uses an innovative approach in describing social time, combining personages into one space and time area using original linguistic sty-listic techniques. In addition, the article makes an attempt to explore the problem of the nonlinear flow of time in a literary text, making the problem of studying social time in literature and language relevant and requiring further development.
Social ulighed på professionsbacheloruddannelser
Authors: Grøndahl Glavind Johanne , Graversgaard Hansen Ditte , Bang-Kristjansen Søren 
Published: May 2024

Abstract
Denne artikel har til formål at kortlægge den eksisterende viden om social ulighed på professionsbacheloruddannelser i Danmark. Fokus er på betydningen af socio-økonomisk baggrund for professionsbachelorstuderendes uddannelsesforløb. Forskningsspørgsmålet besvares gennem et rapid review af nyere dansk og europæisk litteratur på området. Ud af 1107 fremsøgte referencer på (inter)nationale søgedatabaser og håndholdt søgning af yderligere litteratur levede i alt 34 publikationer op til vores søgekriterier. Disse publikationer er inddelt i et uddannelsesforløbs fire faser: 1) optag, 2) faglig udvikling og social trivsel, 3) gennemførelse og frafald og 4) overgang til arbejdsmarkedet og videreuddannelse. Kortlægningen viser, at betydningen af socio-økonomisk baggrund for optaget på professionsbacheloruddannelser er relativt velbelyst i forskningslitteraturen, mens der mangler viden om, hvilken betydning den sociale baggrund har for professionsbachelorstuderendes uddannelsesforløb. Særligt er litteraturen sparsom og tvetydig, når det gælder professionsbachelorstuderendes faglige udvikling, trivsel og frafald.
Nutritional Quality and Antioxidant Properties of Roselle-Tiger Nut Beverage
Authors: N.P. Mtam, , T.T. Iombor, 
Published: May 2024

Background: A beverage is a liquid prepared from cereals, grains and leaves/calyxes for human consumption. Beverages are classified into alcoholic and non-alcoholic beverages.
Objective: The study evaluated the nutritional quality and antioxidant properties of Roselle-tiger nut beverage.
Methods: Roselle-tiger nut beverage was produced from the control samples roselle and tiger nut (% v/v) using the ratios 100:0 Roselle beverage, 0:100 tiger nut beverage and 80:20 Roselle-tiger nut beverage. Subsequently, Proximate, mineral, phytochemical compositions, antioxidants properties and sensory properties were determined using established methods.
Results: There was an elevation in protein (16.29±2.39a) carbohydrate (11.08±9.59a), crude protein (16.29±2.39a) and ash content (3.09±0.56a) but a decrease in moisture and crude fat content. Also, an increase in Sodium (0.09±0.01b), Zinc (0.21±0.00b) and Copper (0.09±0.00b) content with a decrease in Potassium, Phosphorus, Manganese, Magnesium, Calcium and Iron levels. For phytochemical compositions, an increase in flavonoids (1.73±0.43a), saponins (1.25±0.75a) and alkaloids (1.36±0.13a) contents with a decrease in tannins, oxalates and phytate contents was observed. There was an elevation in free radical scavenging activity (0.36±0.00ab) and ferric reducing power (0.32±0.00c) but a decrease in hydroxyl scavenging activity and metal chelating ability. Sample MNP836 of Roselle-tiger nut beverage was the most preferred by panelists for appearance (8.10), taste (8.24), flavor (8.38), mouth feel (8.38) and overall acceptability (8.48).
Conclusion: Substitution of roselle beverage with 20% tiger nut beverage improved the nutritional quality of roselle-tiger nut beverage.
Effect of Potting Mixture and Polybag Size on Growth and Flowering of Asiatic Lily (Lilium asiaticum var. Nashville) under Protected Condition
Authors: Geethan Anupama , Bahadur Vijay , Joseph Annjoe V 
Published: May 2024

An experiment on recognizing the significance of cultivating lilies under polyhouse conditions, this study contributes the valuable insights to the cultivation practices of Asiatic lilies, focusing on the pivotal roles of potting mixture composition and polybag size. Healthy bulbs of each cultivar were freshly planted in various media compositions in different polybag size within a protected environment. From the present investigation, it is concluded that the treatment 12 x 12 polybag size combined with Garden soil + Vermicompost + Cocopeat (1:1:2) was found in superior among other treatments in terms of plant height (69.30cm), leaf length (8.60 cm), leaf width (3.03 cm), number of flower buds/plant (4.60), days to appearance of first flower bud (40.10), flower bud length (8.43 cm), stalk length (68.15 cm), weight of bulb per plant (64.75g), self life of flower spike (15.22 days), number of flowers per 250 m2 (10032.75). The study concluded that, the lilies readily respond to various medium for cultivation and 12 x 12 Polybag combined with potting mixture Garden soil + Vermicompost + Cocopeat (1:1:2) observed to be the best for plant growth and flowering of Asiatic lily under protected condition.
Chondromodulin 1 stabilizes the chondrocyte phenotype and inhibits endochondral ossification of porcine cartilage repair tissue
Authors: Klinger Patricia , Surmann‐Schmitt Cordula , Brem Matthias , Swoboda Bernd , Distler Jörg H. , Carl Hans‐Dieter , von der Mark Klaus , Hennig Friedrich F. , Gelse Kolja 
Published: March 2011

AbstractObjectiveTo investigate the effect of chondromodulin 1 on the phenotype of osteochondral progenitor cells in cartilage repair tissue.MethodsSelf‐complementary adeno‐associated virus (AAV) vectors carrying chondromodulin 1 complementary DNA (AAV‐Chm‐1) were applied to cartilage lesions in the knee joints of miniature pigs that were treated by the microfracture technique. Alternatively, isolated porcine osteochondral progenitor cells were infected with AAV‐Chm‐1 or with AAV‐GFP control vectors ex vivo prior to being transplanted into cartilage lesions in which the subchondral bone plate was left intact. The quality of the repair tissue and the degree of endochondral ossification were assessed by histochemical and immunohistochemical methods. The effects of chondromodulin 1 overexpression were also analyzed by angiogenesis assays and quantitative reverse transcriptase–polymerase chain reaction.ResultsAAV‐Chm‐1–infected cells efficiently produced chondromodulin 1, which had strong antiangiogenic effects, as verified by the inhibition of tube formation of endothelial cells. Gene expression analyses in vitro revealed the cell cycle inhibitor p21WAF1/Cip1 as one target up‐regulated by AAV‐Chm‐1. Direct application of AAV‐Chm‐1 vectors into microfractured porcine cartilage lesions stimulated chondrogenic differentiation of ingrowing progenitor cells, but significantly inhibited terminal chondrocyte hypertrophy, the invasion of vessel structures, and excessive endochondral ossification, which were otherwise observed in untreated lesions. Indirect gene transfer, with infection of porcine osteochondral progenitor cells by AAV‐Chm‐1 ex vivo, also supported chondrogenic differentiation of these transplanted cells. AAV‐Chm‐1–infected cells maintained a chondrocyte‐like phenotype and formed a hyaline‐like matrix that was superior to that formed by uninfected or AAV‐GFP–infected cells.ConclusionOur findings indicate that the antiangiogenic factor chondromodulin 1 stabilizes the chondrocyte phenotype by supporting chondrogenesis but inhibiting chondrocyte hypertrophy and endochondral ossification.