bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery
Authors: Li Tian-Hao , Sun Xiong , Li Cheng-Guo , Yin Yu-Ping , Tao Kai-Xiong 
Published: February 2025

BACKGROUND
Coagulation status is closely related to the progression of malignant tumors. In the era of neoadjuvant immunochemotherapy (NICT), the prognostic utility of coagulation indicators in patients with locally advanced gastric cancer (LAGC) undergoing new treatments remains to be determined.
AIM
To determine whether hypercoagulation is an effective prognostic indicator in patients with LAGC who underwent radical resection after NICT.
METHODS
A retrospective analysis of clinical data from 104 patients with LAGC, who underwent radical resection after NICT between 2020 and 2023, was performed. D-dimer and fibrinogen concentrations were measured one week before NICT, and again one week before surgery, to analyze the association between these two indicators and their combined indices [non-hypercoagulation (D-dimer and fibrinogen concentrations within the upper limit of normal) vs hypercoagulation (D-dimer or fibrinogen concentrations above the upper limit of normal)] with prognosis. After radical resection, patients were followed-up periodically. The median follow-up duration was 21 months.
RESULTS
Data collected after NICT revealed that the three-year overall survival (OS) and disease-free survival (DFS) rates the non-hypercoagulation group were significantly better than those in the hypercoagulation group [94.4% vs 78.0% (P = 0.019) and 87.0% vs 68.0% (P = 0.027), respectively]. Multivariate analysis indicated that hypercoagulation after NICT was an independent factor for poor postoperative OS [hazard ratio (HR) 4.436, P = 0.023] and DFS (HR 2.551, P = 0.039). Pre-NICT data demonstrated no statistically significant difference in three-year OS between the non-hypercoagulation and hypercoagulation groups (88.3% vs 84.1%, respectively; P = 0.443).
CONCLUSION
Hypercoagulation after NICT is an effective prognostic indicator in patients with LAGC undergoing radical gastrectomy.
Ventrículo derecho de doble cámara en un paciente con miocardiopatía hipertrófica no obstructiva. Reporte de caso
Authors: Iroulart Juan María , Ferrero Joaquín , Blanco Rocío , Licht Roshan , Miceli Ana , Pellegrini María Natalia , Pérez de Arenaza Diego , Pizarro Rodolfo 
Published: February 2025

We present the case of a 42-year-old male patient with a history of bilateral lung transplantation and chronic graft dysfunction. The patient presented to the adult emergency department due to acute heart failure. During his stay in the emergency room and in outpatient follow-up, cardiac multi-imaging led to the diagnosis of double-chambered right ventricle with associated hypertrophic cardiomyopathy. Given the presence of advanced lung disease and poor adherence to immunosuppressant medication as well as clinical follow-ups, the patient was deemed unsuitable for re-lung transplantation. The optimization of his immunosuppressive medication was prioritized, and beta-blockers were added as part of the treatment for dynamic right ventricular outflow obstruction. He was referred to pulmonary rehabilitation, currently showing a partially favorable evolution to functional class II.
Implementasi Multimedia Audiovisual dalam Pembelajaran Akidah Akhlak untuk Meningkatkan Prestasi Belajar Siswa di MTSN 2 Surakarta
Authors: Putri Salsabilla Septiana , Mustofa Triono Ali 
Published: February 2025

Penelitian ini bertujuan untuk mengetahui implementasi multimedia audiovisual dalam pembelajaran akidah akhlak di MTs N 2 Surakarta, dengan tujuan untuk meningkatkan prestasi belajar siswa. metode yang digunakan adalah studi kasus kualitatif, yang melibatkan observasi langsung dikelas dan wawancara dengan guru akidah akhlak. hasil penelitian menunjukkan bahwa penggunaan media audiovisual, seperti animasi dan video, secara signifikan meningkatkan keterlibatan siswa, pemahaman, dan resistensi materi. Meskipun terdapat kendala seperti keterbatasan waktu, teknis, dan koneksi internet yang tidak stabil, faktor pendukung seperti infrastruktur teknologi yang memadai, keterampilan guru, dan minat belajar siswa yang tinggi berkontribusi positif terhadap efektivitas pembelajaran. Penelitian ini menyimpulkan bahwa multimedia dapat secara efektif meningkatkan kinerja akademik siswa dalam akidah akhlak, menjadikan pembelajaran lebih konkret dan mudah diakses. Prospek kedepan mencakup peningkatan infrastruktur teknologi, pelatihan guru dan menciptakan suasana belajar yang kondusif, serta sarana untuk penelitian lebih lanjut guna mengeksplorasi, metode dan media pembelajaran lainnya. dengan demikian, diharapkan penelitian ini dapat memotivasi para pendidik untuk mengadopsi metode pengajar yang inovatif dan memberikan solusi praktis untuk meningkatkan efektivitas pembelajaran dikelas.
Analysis of Selected Digital and Connectivity Policies in Canada: Implications for Rural-Living British Columbians
Authors: Seaton Cherisse L. , Rush Kathy L. , Leimbigler Betsy , Li Eric Ping Hung 
Published: February 2025

Abstract
This article’s objective is to provide an overview of the implementation and effects of selected digital connectivity policies impacting rural regions in British Columbia, Canada. The article identifies four key federal-level policies/strategies and two provincial-level programs and synthesized publicly available information regarding the implementation and effects of each. The analysis was supplemented with open-ended survey responses from rural British Columbians. The policies emphasized universal connectivity targets and funding programs, with challenges related to delays and “last-mile” connectivity. Survey respondents highlighted positive impacts of recent connectivity for some residents and skepticism about universal coverage and concerns about affordability for others.
Education of Diarrhea in Toddlers Treatment for Moms in Kalisat Village, Jember Regency
Authors: Maulani Dyan , Yolanda Febiocti Rizka , Ilma Zazila Faiza , Abu Bakar Muhammad , Andesia Putri Artika Yunita 
Published: February 2025

Diarrhea is an environmental disease that is the main cause of morbidity and death. Diarrhea is a digestive canal infection that is a health problem in the world, including Indonesia. The percentage of toddler deaths due to diarrhea in Indonesia is quite high, namely around 4.55%. Health education about treating diarrhea is one way to reduce the incidence of diarrhea in the community. This activity aims are to provide knowledge about the causes of diarrhea, its symptoms, how to treat it, and preventive measures in Kalisat Village, Jember Regency. The method is to educate mothers of the Posyandu in Kalisat Village. The results of the activity showed active participation in the material presented and succeeded in bridging public health knowledge. It is hoped that this activity can continue and have a positive impact on the health of the people of Kalisat Village in the future, preventing cases of toddler deaths caused by diarrhea.
De Laudato Si' À Laudate Deum:
Authors: Brasileiro Eduardo 
Published: February 2025

A Carta Encíclica Laudato Si', publicada pelo Papa Francisco em 24 de maio de 2015, é notável por várias razões. O seu impacto é reconhecido com o impacto semelhante causado pela Encíclica Rerum Novarum do Papa Leão XIII, que abordou a condição operária em seu tempo e falava da transição global do mundo camponês para o mundo industrial. Assim como a Rerum Novarum, hoje, o Papa Francisco provoca um impacto semelhante com a Laudato Si' ao tratar do importante tema do cuidado com a casa comum e da transição do mundo industrial para o mundo financeirizado.
Ao abordar a crise socioambiental, muito melhor traduzida por crise ecológica, estamos tratando da primeira encíclica social de Francisco e a primeira encíclica socioecológica do magistério da Igreja Católica. Ou seja, Francisco constrói uma integração entre as dinâmicas sociais e ecológicas contemporaneizando os desafios sociopolíticos, econômicos e culturais a serem refletidos e transformados. Contudo, apesar do enorme impacto causado pela Encíclica Laudato Si’, há enormes desafios postos e uma disputa global para os rumos das políticas econômicas no mundo; e cientes desses assustadores dados, surge a Exortação Apostólica Laudate Deum, lançada em 04 de outubro de 2023 e pode ser interpretada como um grito do Papa Francisco para uma mudança de rota nas políticas nacionais e internacionais.
Nosso objetivo neste ensaio é compreender essa crise ecológica, analisando seus sintomas e raízes, e, ao mesmo tempo, identificando caminhos para enfrentá-la e superá-la à luz da Encíclica Laudato Si’[1] (LS) e da Exortação Apostólica Laudate Deum[2] (LD).

[1] Será referida como LS, nas menções seguintes e nas referências curtas.
[2] Será referida como LD, nas menções seguintes e nas referências curtas.
Cattle Instance Segmentation by Transfer Learning Approach Using Deep Learning Models for Sustainable Livestock Farming
Authors: Bello Rotimi-Williams , A. Owolawi Pius , A. van Wyk Etienne , Tu Chunling 
Published: February 2025

Image segmentation of animal instances is among the applications of artificial intelligence that recently emerged for sustainable livestock farming. This approach to sustainable livestock farming has become a practical avenue which several precision livestock farming researchers are utilizing to achieve their aims. Artificial intelligence involves several complex tasks including video and image processing. Moreover, the large volume of data required to train deep learning models makes these tasks more complex. However, with the emerging technology of transfer learning, these challenges have been remarkably mitigated. In this study, a system suitable for sustainable livestock farming is proposed using techniques of transfer learning and deep learning models for animal detection and recognition in a farm environment. We evaluated the proposed transfer learning method of the Enhanced Mask R-Convolution Neural Networks (CNN) by comparing it to other two deep learning models, namely Mask R-CNN and Faster R-CNN, on the same dataset using evaluation metric. The Enhanced Mask R-CNN obtained promising results of 0.2 s (computing time) and 97% (mAP), higher than the results obtained by the other two deep learning models. The findings in this study reveal the capacity of transfer learning as an approach for addressing the challenges in segmenting cattle images needed to improve precision livestock farming for sustainable agriculture.
Study of Heavy Metal Accumulation in Common Carp (Cyprinus Carpio L.) Tissues as an Indicator of Sustainable Development in Aquatic Environments
Authors: Kadhim Ban Salman , Ali Abeer Salim , Ahmed Adnan Jawad 
Published: February 2025

The study was conducted to determine the extent of heavy metal accumulation in aquatic organisms important for consumption and to assess the reflection of the aquatic environment in Wasit Governorate, Iraq. Samples were taken from three locations: the first from the river, the second from floating cages, and the third from earthen ponds, as these two systems are the most widespread for fish farming in Iraq.
The results showed that the gill tissues were the most affected by the environment due to their direct contact with the aquatic surroundings. It was observed that the accumulation rates of these elements in fish muscle tissues were the lowest compared to liver and gill tissues. All concentrations were within the permissible limits for human consumption. The results can help predict the state of the aquatic environment in Iraq and work towards the sustainable development of water and animal resources.
THE MODERATE PERSPECTIVE OF YUSUF AL-QARDHAWI ON CAREER WOMEN
Authors: Zunita Hidayatul Chusna  , ITA  MA'RIFATUL FAUZIYAH  , Sandi Yoga Pradana  , Intan Amalia Humala Ababil  , Mu'izah Magfiroh  
Published: February 2025

Women and their role in society has been a long and often controversial topic of discussion in Islamic history. On the one hand, some scholars interpret the role of women as limited to housewives and taking care of the family. But on the other hand, there are scholars who provide more open space for women to have a career outside the home. One of the leading figures who has a moderate view on this issue is Yusuf Al-Qardhawi. This paper examines his moderate views by exploring his thoughts on career women while still considering the rules of sharia and the social realities of modern society. He is one of the leading contemporary scholars on career women. Using the literature review method of Al-Qardhawi's works, this research presents the key points of his views. Al-Qardhawi views that women have the right to work and have a career outside the home, as long as the work is in accordance with women's nature and does not violate the boundaries of Islamic law. He emphasizes the need for balance between a woman's role as a housewife and career. Women should prioritize their primary obligations of taking care of the household and educating children before choosing a career. If women are forced to work due to economic factors or the absence of other breadwinners in the family, then women are allowed to have a career while still observing the Shari'ah rules in interacting with the opposite sex and maintaining their honor.
Voices from the Fringes. A Discourse Analysis of Nicola Sturgeon’s Speech on Scotland’s Place in the World
Authors: Tăbăcaru-Stoian Gabriela 
Published: February 2025

<p dir="ltr"><span>This chapter aims to present a discourse analysis of the First Minister’s speech. Language is not merely supposed to be a means of communicating information, but also a tool for compelling conclusions, establishing or denying claims: “Discourse analysis sees texts as sites in which social meanings are formed and reproduced, social identities are shaped and social facts are established”</span><span>, while discourse alone “is a systematic ordering of language which involves rules, terminology and conventions. They shape specific ways of speaking and understanding. It is a group of statements which provide a language as a way for representing a particular kind of knowledge about a topic. […] Critical discourse analysis is concerned with the social and political context of discourse, based on the view that language is not only conditioned by these contexts, but itself helps constitute them.”</span></p><p dir="ltr"><span>British identity can very well be defined by analysing the way Scotland promotes its international image. In her speech, Nicola Sturgeon addresses topics like immigration, climate change, Brexit and Scottish independence, offering a full and complex picture of her nation’s state of affairs, as to give Scots a voice through her own. </span></p>
The Advertising Discourse in the Fashion Industry
Authors: Munteanu Bianca Georgiana 
Published: February 2025

<p dir="ltr"><span>The contemporary advertising discourse constitutes a highly fertile ground for pragmalinguistic, rhetorical, and stylistic analysis due to its effective utilization of persuasion strategies, lexical creativity, the opposition between verbal and non-verbal elements, and stylistic contrasts. This study aims to provide, on the one hand, an analysis of advertising within the fashion industry and, on the other hand, an examination of consumer behavior and the process of adaptation to the evolving consumer society. The objective of the research is to explore, explain, and describe this phenomenon to facilitate a deeper understanding of both advertising itself and its relationship with members of the consumer society. The primary goal of this study is to develop a model for analyzing advertising discourse, with a focus on elucidating its pragmatic significance. The analysis is centered on interpreting both linguistic and extralinguistic components of discourse, thereby enabling the identification and projection of its pragmatic aspects across different levels of language.</span></p>
Approaches and methods used to bring together Indigenous and Environmental science Knowledge in environmental research: A systematic map protocol
Authors: Pirie Emma , Whillans Tom , Knopp Jennie , Furgal Chris 
Published: June 2024

Abstract

The bringing together of multiple knowledge sources, such as Indigenous knowledge (IK) and Environmental science Knowledge (ESK), is a topic of considerable interest and significance in environmental research. In the areas of resource management for example, the bringing together of IK and ESK datasets has raised considerable interest for its potential to increase understanding and provide insights into complex phenomena such as the effects of climate change and variability on wildlife health and distribution.

The potential benefits that exist from merging these knowledge sources have been widely acknowledged. However, navigating the complex processes involved in knowledge linking continues to pose significant challenges. This systematic mapping protocol will guide the collection and analysis of literature to examine the approaches and methods used in published studies that aim to bring together Indigenous and Environmental science Knowledge in environmental research. The particular focus of this examination is placed on identification of the types of approaches and methods used to merge IK and ESK datasets at the stages of data analysis, results, and interpretation/discussion in the research process.

Through a scoping exercise, a draft search string was developed based on a predetermined list of keywords. Consultation was held with a senior Indigenous scholar to advise on the keywords used and consideration for IK likely to be represented in the collected literature. The final search string will be applied to online bibliographic databases to collect studies published in peer‐reviewed journals. The final capture of the search will be screened in two stages: (1) at the level of title and abstract and (2) at full‐text.

All studies included will be coded using a standardised coding template and a narrative synthesis approach will be used to identify patterns in the evidence, including knowledge gaps and clusters.

Practical implication: The resulting systematic map, following the outlined procedures in this protocol and considering guidelines from the Collaboration for Environmental Evidence (CEE) and Reporting standards for Systematic Evidence Syntheses (ROSES), can serve to support and inform future research endeavours engaged in working towards the linking of IK and ESK, with practical implications for communities and policymakers.
An Engineered Anisotropic Skeletal Muscle Organoid‐on‐a‐Chip for Deciphering Muscle Response under Intermittent Hypoxia
Authors: Li Jiao , Zhang Weihua , Liu Anqi , Lu Yun , Yu Liming , Liu Xue , Sun Liangyan , Zhao Bingjiao , Tong Xianqin , Liu Tingjiao , Liu Yuehua 
Published: June 2024

AbstractGenerating highly organized skeletal muscle tissues that mimics the cellular alignment, maturation, and contraction of native skeletal muscle remains a challenge in disease modeling and regenerative therapies. Existing methodologies are constrained by complexity in fabrication and difficulty in achieving aligned 3D myofibers. Here, a functional skeletal muscle organoid‐on‐a‐chip (SMO) is engineered by establishing mechanical boundary constraints at either end of the cell‐laden extracellular matrix hydrogel within polydimethylsiloxane microstructures to promote the formation of an anisotropic biophysical microenvironment in tissues. The linearly aligned tissue, featuring multinucleated myofibers with distinct cross‐striations, exhibited a positive force‐frequency relationship and stable calcium transients under electrical stimulation. SMOs applicability is demonstrated by systematically evaluating muscle response to varying degrees of intermittent hypoxia. Murine‐ or human‐derived SMOs revealed that, with increasing hypoxia severity, muscles transitioned from a compensatory phase‐characterized by enhanced contractile function, vacuolation and hypertrophic‐like changes in myofibers, fiber type switching, and metabolic shift, to a decompensatory stage, paralleling in vivo muscle responses and highlighting interspecies differences. Human‐derived SMOs are also utilized to assess self‐repair capabilities and pharmaceuticals protective effects on damaged muscle. Together, the platform, with its simplicity of operation and reliable phenotypic readouts, demonstrates significant potential for future disease modeling and regenerative therapies.
Liquid Crystal Elastomer Hollow Fibers as Artificial Muscles with Large and Rapid Actuation Enabled by Thermal‐Pneumatic Enhanced Effect
Authors: Ma Jiazhe , Wang Yunpeng , Sun Jiahao , Yang Zhongqiang 
Published: June 2024

AbstractLiquid crystal elastomer (LCE) has large and reversible deformation under stimulation, making it an ideal material for artificial muscles. Currently, multi‐stimulus responsive LCE actually responds to each stimulus independently rather than responding to several stimuli simultaneously. Achieving an enhanced effect from concurrent stimuli is still a challenge, which requires a new stimulus‐response mechanism. This work develops a novel and facile solvent evaporation‐assisted template method to prepare LCE hollow fiber (LCEHF) with axial alignment. Taking advantage of the enhanced effect of heat‐induced phase transition and mechanical force‐induced orientation transition of mesogens, the LCEHF under both heat and pressure can produce a large contraction ratio of ≈50%, which is higher than 42% of thermal stimulation or 27% of pneumatic stimulation. It can also enhance the respective response and recovery speed of LCEHF to 300 and 3700 times of pneumatic actuation. Additionally, the enhanced effect lowers the actuation temperature much below the phase transition temperature, imparting LCEHF with high mechanical performance during actuation. Furthermore, the dual thermal‐pneumatic responsive LCEHF can mimic human biceps and cause large and rapid bending of an artificial arm reversibly. This new actuation methodology sheds new light on improving LCE actuation performance and broadens its application scenarios.
Nanoarchitectonics of Laser Induced MAX 3D‐Printed Electrode for Photo‐Electrocatalysis and Energy Storage Application with Long Cyclic Durability of 100 000 Cycles
Authors: Nouseen Shaista , Deshmukh Sujit , Pumera Martin 
Published: June 2024

Abstract3D printing, a rapidly expanding domain of additive manufacturing, enables the fabrication of intricate 3D structures with adjustable fabrication parameters and scalability. Nonetheless, post‐fabrication, 3D‐printed materials often require an activation step to eliminate non‐conductive polymers, a process traditionally achieved through chemical, thermal, or electrochemical methods. These conventional activation techniques, however, suffer from inefficiency and inconsistent results. In this study, a novel chemical‐free activation method employing laser treatment is introduced. This innovative technique effectively activates 3D‐printed electrodes, which are then evaluated for their photo and electrochemical performance against traditional solvent‐activated counterparts. The method not only precisely ablates surplus non‐conductive polymers but also exposes and activates the underlying electroactive materials. The 3D‐printed electrodes, processed with this single‐step laser approach, exhibit a notably low overpotential of ≈505 mV at a current density of −10 mA cm−2 under an illumination wavelength of 365 nm. These electrodes also demonstrate exceptional durability, maintaining stability through >100 000 cycles in energy storage applications. By amalgamating 3D printing with laser processing, the creation of electrodes with complex structures and customizable properties is enabled. This synergy paves the way for streamlined production of such devices in the field of energy conversion and storage.