bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rational design approach for amino acid supplementation in hepatocyte culture
Authors: Yang Hong , Roth Charles M. , Ierapetritou Marianthi G. 
Published: April 2009

AbstractImprovement of culture media for mammalian cells is conducted via empirical adjustments, sometimes aided by statistical design methodologies. Here, we demonstrate a proof of principle for the use of constraints‐based modeling to achieve enhanced performance of liver‐specific functions of cultured hepatocytes during plasma exposure by adjusting amino acid supplementation and hormone levels in the medium. Flux balance analysis (FBA) is used to determine an amino acid flux profile consistent with a desired output; this is used to design an amino acid supplementation. Under conditions of no supplementation, empirical supplementation, and designed supplementation, hepatocytes were exposed to plasma and their morphology, specific cell functions (urea, albumin production) and lipid metabolism were measured. Urea production under the designed amino acid supplementation was found to be increased compared with previously reported (empirical) amino acid supplementation. Not surprisingly, the urea production attained was less than the theoretical value, indicating the existence of pathways or constraints not present in the current model. Although not an explicit design objective, albumin production was also increased by designed amino acid supplementation, suggesting a functional linkage between these outputs. In conjunction with traditional approaches to improving culture conditions, the rational design approach described herein provides a novel means to tune the metabolic outputs of cultured hepatocytes. Biotechnol. Bioeng. 2009;103: 1176–1191. © 2009 Wiley Periodicals, Inc.
A two‐phase partitioning airlift bioreactor for the treatment of BTEX contaminated gases
Authors: Littlejohns Jennifer V. , Daugulis Andrew J. 
Published: April 2009

AbstractThis investigation characterizes a novel 11 L airlift two‐phase partitioning bioreactor (TPPB) for the treatment of gases contaminated with a mixture of benzene, toluene, ethylbenzene, and o‐xylene (BTEX). The application of the TPPB technology in an airlift bioreactor configuration provides a novel technology that reduces energy intensity relative to traditional stirred tank TPPB configurations. The addition of a solid second phase of silicone rubber beads (10%, v/v) or of a liquid second phase of silicone oil (10%, v/v) resulted in enhanced performance of the airlift bioreactor relative to the single phase case, with 20% more BTEX being removed from the gas phase during an imposed transient loading. During a 4 h loading step change of three times the nominal loading (60 g m−3 h−1), overall removal efficiencies for the airlift TPPBs containing a liquid or solid phase remained above 75%, whereas the single phase airlift had an overall removal efficiency of 47.1%. The airlift TPPB containing a silicone rubber second phase was further characterized by testing performance during steady‐state operation over a range of loadings and inlet gas flow rates in the form of a 32 factorial experimental design. Optimal operating conditions that avoid oxygen limitations and that still have a slow enough gas flow rate for sufficient BTEX transfer from the gas phase to the working volume are identified. The novel solid–liquid airlift TPPB reduces energy inputs relative to stirred tank designs while being able to eliminate large amounts of BTEX during both steady‐state and fluctuating loading conditions. Biotechnol. Bioeng. 2009;103: 1077–1086. © 2009 Wiley Periodicals, Inc.
Energy from algae using microbial fuel cells
Authors: Velasquez‐Orta Sharon B. , Curtis Tom P. , Logan Bruce E. 
Published: April 2009

AbstractBioelectricity production from a phytoplankton, Chlorella vulgaris, and a macrophyte, Ulva lactuca was examined in single chamber microbial fuel cells (MFCs). MFCs were fed with the two algae (as powders), obtaining differences in energy recovery, degradation efficiency, and power densities. C. vulgaris produced more energy generation per substrate mass (2.5 kWh/kg), but U. lactuca was degraded more completely over a batch cycle (73 ± 1% COD). Maximum power densities obtained using either single cycle or multiple cycle methods were 0.98 W/m2 (277 W/m3) using C. vulgaris, and 0.76 W/m2 (215 W/m3) using U. lactuca. Polarization curves obtained using a common method of linear sweep voltammetry (LSV) overestimated maximum power densities at a scan rate of 1 mV/s. At 0.1 mV/s, however, the LSV polarization data was in better agreement with single‐ and multiple‐cycle polarization curves. The fingerprints of microbial communities developed in reactors had only 11% similarity to inocula and clustered according to the type of bioprocess used. These results demonstrate that algae can in principle, be used as a renewable source of electricity production in MFCs. Biotechnol. Bioeng. 2009;103: 1068–1076. © 2009 Wiley Periodicals, Inc.
Cover Picture: Total Syntheses of Amphidinolides B1, B4, G1, H1 and Structure Revision of Amphidinolide H2 (Chem. Eur. J. 16/2009)
Authors: Fürstner Alois , Bouchez Laure C. , Morency Louis , Funel Jaques‐Alexis , Liepins Vilnis , Porée François‐Hugues , Gilmour Ryan , Laurich Daniel , Beaufils Florent , Tamiya Minoru 
Published: April 2009

AbstractHighly cytotoxic amphidinolide macrolides have been prepared in a highly convergent and largely catalysis‐based route. In their Full Paper on page 3983 ff., and two subsequent papers, A. Fürstner et al. describe the total synthesis and biological evaluation of amphidinolide B1, B4, G1, H1, H2, V, X, and Y, as well as several analogues.magnified image
ChemInform Abstract: Location of Deuterium Positions in the Proton‐Conducting Perovskite BaCe0.4Zr0.4Sc0.2O2.90 ·xD2O by Neutron Powder Diffraction.
Authors: Azad Abul K. , Irvine John T. S. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Luminescence Properties of Sr2ZnWO6:Eu3+ Phosphors.
Authors: Zhang Xueliang , Li Zhaosheng , Zhang Haitao , Ouyang Shuxin , Zou Zhigang 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalyst‐Free Growth of Quasi‐Aligned Nanorods of Single Crystal Cu3Mo2O9 and Their Catalytic Properties.
Authors: Chu W. G. , Wang H. F. , Guo Y. J. , Zhang L. N. , Han Z. H. , Li Q. Q. , Fan S. S. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: {[SmCl(en)4][In2Te4]}n: An Indium Telluride with a One‐Dimensional Sinusoidal Chain.
Authors: Li Chun‐Ying , Zhou Jian , Zhang Yong , Bian Guo‐Qing , Dai Jie 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of 1,5‐Diketones. A New Synthetic Approach to Unsaturated 1,5‐Diketones.
Authors: Pchelintseva N. V. , Fedotova O. V. , Kolevatova Ya. G. , Burov A. M. , Men'shova M. A. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold‐Catalyzed Cycloisomerization of Cyclopropyl Alkynyl Acetates: A Versatile Approach to 5‐, 6‐, and 7‐Membered Carbocycles.
Authors: Zou Yue , Garayalde David , Wang Quanrui , Nevado Cristina , Goeke Andreas 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Platinum‐Catalyzed Cycloisomerization Reaction of 1,6‐Enyne Coupling with Rearrangement of Propargylic Esters.
Authors: Lu Li , Liu Xue‐Yuan , Shu Xing‐Zhong , Yang Ke , Ji Ke‐Gong , Liang Yong‐Min 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iodination of Aromatic Compounds Using Potassium Iodide and Hydrogen Peroxide.
Authors: Reddy K. Suresh Kumar , Narender N. , Rohitha C. N. , Kulkarni S. J. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient and Stable Palladium Nanocatalysts Supported on an Ionic Liquid Modified Xerogel.
Authors: Safavi Afsaneh , Maleki Norouz , Iranpoor Nasser , Firouzabadi Habib , Banazadeh Ali Reza , Azadi Roya , Sedaghati Fatemeh 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Coupling of Alcohols with Alkenylsilanes Catalyzed by Indium Trichloride or Bismuth Tribromide.
Authors: Nishimoto Yoshihiro , Kajioka Masayuki , Saito Takahiro , Yasuda Makoto , Baba Akio 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium(0) Nanoparticle Catalyzed Cross‐Coupling of Allyl Acetates and Aryl and Vinyl Siloxanes.
Authors: Dey Raju , Chattopadhyay Kalicharan , Ranu Brindaban C. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Unexpected Tandem Enantioselective Michael Addition/Oxa‐Nucleophilic Rearrangement Reaction of β,γ‐Unsaturated α‐Keto Esters Catalyzed by Cinchona Alkaloids.
Authors: Wang Hai‐Feng , Zheng Chang‐Wu , Yang Ying‐Quan , Chai Zhuo , Zhao Gang 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photocycloaddition Reactions of 2‐(Alk‐3‐en‐1‐ynyl)cyclohex‐2‐enones.
Authors: Moebius Janne , Margaretha Paul 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cobalt(II)‐Catalyzed Regio‐ and Stereoselective Hydroarylation of Alkynes with Organoboronic Acids.
Authors: Lin Pao‐Shun , Jeganmohan Masilamani , Cheng Chien‐Hong 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Addition of Diethylzinc to Aromatic Aldehydes Catalyzed by Ti(IV) Complexes of C2‐Symmetrical Chiral BINOL Derivatives.
Authors: Gou Shaohua , Zudeh Jaher M. A. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydroxyalkyl Thiazolines, a New Class of Highly Efficient Ligands for Carbonyl Additions.
Authors: Bauer Michael , Maurer Frauke , Hoffmann Svenja M. , Kazmaier Uli 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: LiClO4‐Accelerated Three‐Component Mannich‐Type Reaction of Diethyl Malonate with Imines: An Efficient Synthesis of β‐Amino Esters under Solvent‐Free Conditions.
Authors: Aryanasab Fezzeh , Saidi Mohammad R. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The BF3·OEt2‐Assisted Conversion of Nitriles into Thioamides with Lawesson′s Reagent.
Authors: Nagl Michael , Panuschka Claudia , Barta Andrea , Schmid Walther 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Micellar Catalysis of Suzuki—Miyaura Cross‐Couplings with Heteroaromatics in Water.
Authors: Lipshutz Bruce H. , Abela Alexander R. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Synthesis of 4‐Keto‐4,5,6,7‐tetrahydrobenzofurans.
Authors: Goncalves Sylvie , Wagner Alain , Mioskowski Charles , Baati Rachid 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Influence of the Position of tert‐Butyl Substituents on Reactivity of Quinone Dimers Yielding Dibenzofuran‐1,4‐diones.
Authors: Hayashi Naoto , Kanda Akifumi , Higuchi Hiroyuki , Ninomiya Keiko 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Enolate Protonations: Friedel—Crafts Reactions with α‐Substituted Acrylates.
Authors: Sibi Mukund P. , Coulomb Julien , Stanley Levi M. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of N‐2‐Aryl‐1,2,3‐triazole Fluorophores via Post‐Triazole Arylation.
Authors: Liu Yuxiu , Yan Wuming , Chen Yunfeng , Petersen Jeffrey L. , Shi Xiaodong 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of Chromans by Iridium‐Catalyzed Asymmetric Hydrogenation of 4H‐Chromenes.
Authors: Valla Carine , Baeza Alejandro , Menges Frederik , Pfaltz Andreas 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Methyl 1‐Imidazolecarbodithioate as a Thiocarbonyl Transfer Reagent: A Facile One‐Pot, Three‐Component Synthesis of Novel 2‐Substituted‐5‐aryl‐1‐oxo‐3‐thioxo‐1,2,3,5,11,11a‐hexahydro‐6H‐imidazo‐ [1,5‐b]‐β‐carbolines.
Authors: Singh Balendu , Sundaram G. S. M. , Misra Nimesh C. , Ila Hiriyakkanavar 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of Pyrido[2,1‐a]isoindoles via a Three‐Component Assembly Involving Benzynes.
Authors: Xie Chunsong , Zhang Yuhong , Xu Peixin 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organocatalytic Asymmetric α‐Aminoxylation/Aza‐Michael Reactions for the Synthesis of Functionalized Tetrahydro‐1,2‐oxazines.
Authors: Lu Min , Zhu Di , Lu Yunpeng , Hou Yuxuan , Tan Bin , Zhong Guofu 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of the CDK‐Inhibitor Paullone by Cyclization of a Deprotonated α‐Aminonitrile.
Authors: Opatz Till , Ferenc Dorota 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Preparation of Cycloalkenyl Boronic Acid Pinacol Esters.
Authors: Rauniyar Vivek , Zhai Huimin , Hall Dennis G. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient and Divergent Synthesis of Cyclophosphamide Analogues from 2‐Arylamino‐3‐acetyl‐5,6‐dihydro‐4H‐pyrans.
Authors: Xiang Dexuan , Huang Peng , Wang Kewei , Zhou Guangyuan , Liang Yongjiu , Dong Dewen 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 4‐(N,N‐Dialkylamino)benzyltriphenylphosphonium Iodides from Hydroxymethyltriphenylphosphonium Iodide and N,N‐Dialkylaniline.
Authors: Davis Matthew C. , Parrish Damon A. 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structures of New Monoterpenes from Thai Herbal Medicine Curcuma comosa
Authors: Nakamura Seikuo , Qu Yang , Xu Fengming , Matsuda Hisashi , Yoshikawa Masayuki 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Five New Diterpenoids, Viteagnusins A—E, from the Fruit of Vitex agnus‐castus
Authors: Ono Masateru , Yamasaki Toru , Konoshita Masatarou , Ikeda Tsuyoshi , Okawa Masafumi , Kinjo Junei , Yoshimitsu Hitoshi , Nohara Toshihiro 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Medicinal Flowers. Part 23. New Taraxastane‐Type Triterpene, Punicanolic Acid (I), with Tumor Necrosis Factor‐α Inhibitory Activity from the Flowers of Punica granatum.
Authors: Xie Yuanyuan , Morikawa Toshio , Ninomiya Kiyofumi , Imura Katsuya , Muraoka Osamu , Yuan Dan , Yoshikawa Masayuki 
Published: April 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.