bluuebunny/crossref_metadata_2025_split huggingface dataset:
Testing quantitative magnetization transfer models with membrane lipids
Authors: Shtangel Oshrat , Mezer Aviv A. 
Published: June 2024

AbstractPurposeQuantitative magnetization transfer (qMT) models aim to quantify the contributions of lipids and macromolecules to the MRI signal. Hence, a model system that relates qMT parameters and their molecular sources may improve the interpretation of the qMT parameters. Here we used membrane lipid phantoms as a meaningful tool to study qMT models. By controlling the fraction and type of membrane lipids, we could test the accuracy, reliability, and interpretability of different qMT models.MethodsWe formulated liposomes with various lipid types and water‐to‐lipids fractions and measured their signals with spoiled gradient‐echo MT. We fitted three known qMT models and estimated six parameters for every model. We tested the accuracy and reproducibility of the models and compared the dependency among the qMT parameters. We compared the samples' qMT parameters with their water‐to‐lipid fractions and with a simple MTnorm (= MTon/MToff) calculation.ResultsWe found that the three qMT models fit the membrane lipids signals well. We also found that the estimated qMT parameters are highly interdependent. Interestingly, the estimated qMT parameters are a function of the membrane lipid type and also highly related to the water‐to‐lipid fraction. Finally, we find that most of the lipid sample's information can be captured using the common and easy to estimate MTnorm analysis.ConclusionqMT parameters are sensitive to both the water‐to‐lipid fraction and to the lipid type. Estimating the water‐to‐lipid fraction can improve the characterization of membrane lipids' contributions to qMT parameters. Similar characterizations can be obtained using the MTnorm analysis.
Interplay of superconductivity and magnetism in the Fe1+yTe1‐xSex iron‐based superconductor: A theoretical study
Authors: Ayalew Kefale , Shiferaw Dagne Atnafu , Mebratie Gedefaw 
Published: June 2024

AbstractThe competition between superconductivity and magnetism has been studied for the ongoing investigation of mechanisms in unconventional superconductors. Fe1+yTe1−xSex is distinct among iron‐based superconductors due to its structural simplicity, comprising solely FeTe/Se layers that are favorable for probing the superconductivity mechanism. The main goal of this article is to focus on the computational investigation of the interplay of magnetism and superconductivity in the Fe1+yTe1−xSex multiband superconductor. From the electronic structure of the Fe1+yTe1−xSex superconductor, a two‐band Hamiltonian model was considered to examine the interplay of magnetism and superconductivity in the Fe1+yTe1‐xSex superconductor. Using Green's function formalism with the Hamiltonian model, the mathematical statements for the superconducting (Sc) gap parameter, spin density wave (SDW) ordering parameter, Sc and magnetic transitional temperatures have been obtained. Using these mathematical expressions, the phase diagram of transition temperatures versus the gap parameters for the Fe1+yTe1‐xSex superconductor has been plotted. The intersection region in the phase diagram of transition temperatures as a function of the SDW order parameter has been plotted to show the possible interplay of superconductivity and magnetism in a Fe1+yTe1‐xSex iron‐based superconductor.
Privacy‐preserving‐based fuzzy filtering for nonlinear networked systems with adaptive‐event‐triggered mechanism and FDI attacks
Authors: Liu Jinliang , Tang Jiahui , Zha Lijuan , Xie Xiangpeng , Tian Engang , Peng Chen 
Published: June 2024

AbstractThis article centers around the privacy‐preserving‐based secure filtering issue for interval type‐2 (IT‐2) fuzzy networked systems with false data injection (FDI) attacks. In order to achieve the goal of privacy preserving and significantly enhancing system security against potential eavesdropping threats, a novel encryption‐decryption mechanism (EDM) is adopted to safeguard the safety of signals across the network. The mechanism encrypts the transmitted signal by introducing artificial noise, secret key, and utilizing randomly selected nodes. This ensures that the actual transmitted data remains invisible to eavesdroppers while minimally the impact on the estimated performance of the proposed EDM. Given the network communication resources are becoming constrained due to the ever‐increasing network traffic, an adaptive event‐triggered mechanism (AETM) is employed to ease network congestion by an adaptively adjustable threshold. Then, various sufficient conditions have been outlined to ensure that the filtering error system meets the prescribed disturbance attenuation level. In the end, a numerical example is presented to evaluate both the precision and effectiveness of the developed algorithms.
Virtual reality testing of emergency scenarios could improve student reactions in the future
Authors: Sutton Halley 
Published: June 2024

Artificial intelligence is infiltrating every sector of college life, from admissions papers to now, research on how virtual reality simulations can improve campus safety. Emergency Management Science and Technology published a paper titled “Experimental Research on College Students’ Emergency Ability and Its Influencing Factors in Virtual Emergency Situations” that examines how AI technology, such as virtual reality simulations, can improve understanding of students’ ability to respond to emergency situations.
Enhancement of Catalytic Activity via Inevitable Reconstruction of the Ni–Mo Interface for Alkaline Hydrogen Oxidation
Authors: Song Xiaoyun , Yang Qimei , Chen Zebi , Zou Kaisheng , Xie Zhenyang , Ding Wei , Wei Zidong 
Published: June 2024

AbstractThe inevitable oxidation of nickel‐metal‐based catalysts exposed to the air will lead to instability and poor reproducibility of a catalytic interface, which is usually ignored and greatly hinders their application for the catalysis of alkaline hydrogen oxidation. The details on the formation of a world‐class nickel‐based HOR catalyst Ni3‐MoOx/C‐500 are reported via an interfacial reconstruction triggered by passive oxidation upon air exposure. Interfacial reconstruction, initiated with various Ni–Mo metal ratios and annealing temperature, can fine‐tune the Ni–Mo interface with an increased work function and a reduced d‐band center. The optimized Ni3‐MoOx/C exhibits a record high mass activity of 102.8 mA mgNi−1, a top‐level exchange current density of 76.5 µA cmNi−2, and exceptional resistance to CO poisoning at 1000 ppm CO for hours. The catalyzed alkaline exchange membrane fuel cell exhibits a maximum power output of 600 mW cm−2 and excellent stability, ranking it as one of the most active non‐precious metals HOR catalysts to date.
Probing Short‐Range Correlations in the van der Waals Magnet CrSBr by Small‐Angle Neutron Scattering
Authors: Rybakov Andrey , Boix‐Constant Carla , Alba Venero Diego , van der Zant Herre S. J. , Mañas‐Valero Samuel , Coronado Eugenio 
Published: June 2024

The layered metamagnet CrSBr offers a rich interplay between magnetic, optical, and electrical properties that can be extended down to the two‐dimensional (2D) limit. Despite the extensive research regarding the long‐range magnetic order in magnetic van der Waals materials, short‐range correlations have been loosely investigated. By using small‐angle neutron scattering (SANS) the formation of short‐range magnetic regions in CrSBr with correlation lengths that increase upon cooling up to ≈3 nm at the antiferromagnetic ordering temperature (T
N
≈ 140 K) is shown. Interestingly, these ferromagnetic correlations start developing below 200 K, i.e., well above T
N. Below T
N, these correlations rapidly decrease and are negligible at low‐temperatures. The experimental results are well‐reproduced by an effective spin Hamiltonian, which pinpoints that the short‐range correlations in CrSBr are intrinsic to the monolayer limit, and discard the appearance of any frustrated phase in CrSBr at low‐temperatures within the experimental window between 2 and 200 nm. Overall, the obtained results are compatible with a spin freezing scenario of the magnetic fluctuations in CrSBr and highlight SANS as a powerful technique for characterizing the rich physical phenomenology beyond the long‐range order paradigm offered by van der Waals magnets.
Applying recent advances in climate adaptation research to urban heat risk management
Authors: Singh Chandni , Ramesh Ananya , Hagenlocher Michael , Shekhar Himanshu , Siemons Anne‐Sophie Sabino , Okunola Olasunkanmi Habeeb , Werners Saskia E. 
Published: June 2024

AbstractThere is unequivocal evidence that anthropogenic climate change is supercharging temperature and precipitation regimes globally. One of the clearest signals of this is seen in current and projected increases in extreme heat, understood as changes in temperature maximums, longer duration heatwaves, and higher night‐time temperatures. Extreme heat has substantial impacts on socio‐ecological systems through direct impacts on human health and labor productivity, crop yields and water security; and second‐order impacts on infrastructure functioning and hazards (e.g., increased fire and drought incidence). These impacts are differentiated and mediated by preexisting vulnerabilities based on who you are, what you do, where you live, and your capacities to prepare for, prevent, cope with and adapt to heat exposure. Nowhere are these increasing and differentiated impacts of heat more visible than in populous, rapidly urbanizing regions. Governments across the world are piloting and implementing heat management strategies, which are variously called heat‐health plans, heat action plans, heat resilience strategies, and so forth. We argue that such actions and policy agendas can benefit from theoretical advances in the climate change vulnerability and adaptation literature. We synthesize five theoretical advances to highlight the need for suites of actions sequenced in pathways that are more sensitive to trade‐offs, center equity as a normative goal of effective adaptation, acknowledge uncertainty and preexisting differential vulnerabilities, leverage lessons from participatory adpatation planning, and are forward‐looking and preparatory actions. We consolidate these advances and develop an approach to inform urban heat risk management.This article is categorized under:
Climate, Nature, and Ethics > Climate Change and Global Justice
Climate and Development > Urbanization, Development, and Climate Change
The Social Status of Climate Change Knowledge > Climate Science and Decision Making
Improved constraints on the variation of the weak scale from Big Bang nucleosynthesis
Authors: Meyer Helen , Meißner Ulf-G. 
Published: June 2024

Abstract
We present an improved calculation of the light element abundances in the framework of Big Bang nucleosynthesis as a function of the Higgs vacuum expectation value v. We compare the methods of our calculation to previous literature including the recently published work of Burns et al. [1]. The PDG result for the 4He abundance can be explained within 2σ by −0.014 ≤ δv/v ≤ 0.026, for deuterium we find the constraint −0.005 ≤ δv/v ≤ −0.001. These bounds are more stringent than what was found earlier.
Cosmological implications of Kalb-Ramond-like particles
Authors: Capanelli Christian , Jenks Leah , Kolb Edward W. , McDonough Evan 
Published: June 2024

Abstract
The Kalb-Ramond field is an antisymmetric, rank-two tensor field which most notably appears in the context of string theory, but has largely been unexplored in the context of cosmology. In this work, motivated by the Kalb-Ramond field in string theory, and antisymmetric tensor fields that emerge in effective field theories ranging from particle physics to condensed matter, we study the primordial production of interacting massive Kalb-Ramond-like-particles (KRLPs). KRLPs contain features of both dark photon and axion models, which can be appreciated via their duality properties. While the massless non-interacting KRLP is dual to a pseudoscalar, and the massive non-interacting KRLP is dual to a pseudovector, the interacting massive KRLP can be distinguished from its scalar and vector counterparts. We study early-universe production of KRLPs via the freeze-in mechanism, considering a ‘dark photon-like’ interaction, an ‘axion-like’ interaction, and a ‘Higgs portal’ interaction, as well as production via cosmological gravitational particle production. We find that as a dark matter candidate, KRLPs can be produced by all of the above mechanisms and account for the relic density of dark matter today for a wide range of masses. Finally, we comment on the potential to obtain both warm and cold dark matter subcomponents, and speculate on observational and experimental prospects.
Sorafenib and edaravone protect against renal fibrosis induced by unilateral ureteral obstruction via inhibition of oxidative stress, inflammation, and RIPK-3/MLKL pathway
Authors: Abou Taha Mohamed A. , Ali Fares E.M. , Saleh Ibrahim G. , Akool El-Sayed 
Published: June 2024

AbstractRenal fibrosis is the common endpoint of nearly all chronic and progressive nephropathies. Cell death and sterile inflammation are the main characteristics of renal fibrosis, which can lead to end-stage renal failure. The inflammatory reaction triggered by tissue damage is strongly related to necroptosis, a type of caspase-independent, regulated cell death. Using an animal model of unilateral ureteral obstruction (UUO), the anti-fibrotic effects of sorafenib (SOF), a multi-kinase inhibitor, and edaravone (EDV), a potent antioxidant and free radical scavenger, were examined in rats with obstructive nephropathy. Experimentally, animals were divided randomly into five groups: sham; UUO; UUO + SOF (5 mg/kg/day, P.O.); UUO + EDV (20 mg/kg/day, P.O.); and UUO + SOF + EDV groups. The kidney function biomarkers, oxidant/antioxidant status, renal mRNA expressions of TNF-α, collagen-1α, protein expressions of RIPK-1, RIPK-3, MLKL, caspase-8, HYP, MPO, and TNF-α were all significantly modulated by UUO. Administration of either SOF or EDV significantly attenuated cellular and molecular changes induced by UUO. Also, histopathological changes were improved. Moreover, SOF in combination with EDV, significantly improved UUO-induced renal fibrosis compared with each drug alone. Collectively, administration of either SOF or EDV or both of them significantly attenuated the rats with obstructive nephropathy, possibly by blocking the RIPK-3/MLKL necroptotic pathway and suppressing renal oxidative stress and inflammation.
A structure-preserving finite element method for the multi-phase Mullins–Sekerka problem with triple junctions
Authors: Eto Tokuhiro , Garcke Harald , Nürnberg Robert 
Published: June 2024

AbstractWe consider a sharp interface formulation for the multi-phase Mullins–Sekerka flow. The flow is characterized by a network of curves evolving such that the total surface energy of the curves is reduced, while the areas of the enclosed phases are conserved. Making use of a variational formulation, we introduce a fully discrete finite element method. Our discretization features a parametric approximation of the moving interfaces that is independent of the discretization used for the equations in the bulk. The scheme can be shown to be unconditionally stable and to satisfy an exact volume conservation property. Moreover, an inherent tangential velocity for the vertices on the discrete curves leads to asymptotically equidistributed vertices, meaning no remeshing is necessary in practice. Several numerical examples, including a convergence experiment for the three-phase Mullins–Sekerka flow, demonstrate the capabilities of the introduced method.
Contribution of Aerobic Cellulolytic Gut Bacteria to Cellulose Digestion in Fifteen Coastal Grapsoid Crabs Underpins Potential for Mineralization of Mangrove Production
Authors: Lee Cheuk Yan , Lee Shing Yip 
Published: June 2024

AbstractGrapsoid crabs (Decapoda: Grapsoidea) inhabiting along the land-sea transition provided various amounts and quality of vascular plant carbon (e.g., fresh mangrove leaf, leaf litter, and mangrove-derived organic carbon) and perform differing levels of herbivory. Other than endogenous cellulase, symbiotic cellulolytic bacteria could also contribute to the crabs’ vascular plant carbon assimilation and mineralization. In this study, we isolated culturable cellulolytic bacteria from three gut regions (i.e., stomach, midgut, and hindgut) of 15 species of grapsoid crabs that inhabit in various coastal habitats (i.e., land margin, mangrove forest, tidal flat, and subtidal area). Bacillus, which was isolated from 11 out of the 15 grapsoid crabs, was the most common genus of culturable prominently cellulolytic bacteria among the target species. Seventy to ninety nine percent of culturable cellulolytic bacteria were removed, and the endoglucanase activity of five species was significantly reduced by 14.4–27.7% after antibiotic treatment. These results suggest that cellulolytic bacteria play a role in assisting mangrove carbon utilization in coastal grapsoid crabs, especially those inhabiting mangrove, mudflat, and subtidal areas. The significantly higher abundance of cellulolytic bacteria and the generally higher hydrolytic capacity of the bacteria in mangrove crab species suggest that they receive more contribution from symbionts for mangrove carbon utilization, while semi-terrestrial crabs seem to depend little on symbiotic cellulase due to the lower abundances.
Ancestral reproductive bias in continuous-time branching trees under various sampling schemes
Authors: Igelbrink Jan Lukas , Ischebeck Jasper 
Published: June 2024

AbstractCheek and Johnston (JMB 86:70, 2023) consider a continuous-time Bienaymé-Galton-Watson tree conditioned on being alive at time T. They study the reproduction events along the ancestral lineage of an individual randomly sampled from all those alive at time T. We give a short proof of an extension of their main results (Cheek and Johnston in JMB 86:70, 2023, Theorems 2.3 and 2.4) to the more general case of Bellman-Harris processes. Our proof also sheds light onto the probabilistic structure of the rate of the reproduction events. A similar method will be applied to explain (i) the different ancestral reproduction bias appearing in work by Geiger (JAP 36:301–309, 1999) and (ii) the fact that the sampling rule considered by Chauvin et al. (SPA 39:117–130, 1991), (Theorem 1) leads to a time homogeneous process along the ancestral lineage.
Genetic/epigenetic effects in NF1 microdeletion syndrome: beyond the haploinsufficiency, looking at the contribution of not deleted genes
Authors: Tritto Viviana , Bettinaglio Paola , Mangano Eleonora , Cesaretti Claudia , Marasca Federica , Castronovo Chiara , Bordoni Roberta , Battaglia Cristina , Saletti Veronica , Ranzani Valeria , Bodega Beatrice , Eoli Marica , Natacci Federica , Riva Paola 
Published: June 2024

AbstractNF1 microdeletion syndrome, accounting for 5–11% of NF1 patients, is caused by a deletion in the NF1 region and it is generally characterized by a severe phenotype. Although 70% of NF1 microdeletion patients presents the same 1.4 Mb type-I deletion, some patients may show additional clinical features. Therefore, the contribution of several pathogenic mechanisms, besides haploinsufficiency of some genes within the deletion interval, is expected and needs to be defined. We investigated an altered expression of deletion flanking genes by qPCR in patients with type-1 NF1 deletion, compared to healthy donors, possibly contributing to the clinical traits of NF1 microdeletion syndrome. In addition, the 1.4-Mb deletion leads to changes in the 3D chromatin structure in the 17q11.2 region. Specifically, this deletion alters DNA-DNA interactions in the regions flanking the breakpoints, as demonstrated by our 4C-seq analysis. This alteration likely causes position effect on the expression of deletion flanking genes.Interestingly, 4C-seq analysis revealed that in microdeletion patients, an interaction was established between the RHOT1 promoter and the SLC6A4 gene, which showed increased expression. We performed NGS on putative modifier genes, and identified two “likely pathogenic” rare variants in RAS pathway, possibly contributing to incidental phenotypic features.This study provides new insights into understanding the pathogenesis of NF1 microdeletion syndrome and suggests a novel pathomechanism that contributes to the expression phenotype in addition to haploinsufficiency of genes located within the deletion.This is a pivotal approach that can be applied to unravel microdeletion syndromes, improving precision medicine, prognosis and patients’ follow-up.
Introduction of day-case robotic liver surgery: a case series from a tertiary hepatobiliary and pancreatic centre
Authors: Yeung Kai Tai Derek , Vellaisamy Rajendran , Hussain Aasim , Mingo Olivia , Raobaikady Ravishankar , Nicol David , Rasheed Shahnawaz , Tekkis Paris , Cunningham David , Jiao Long R. 
Published: June 2024

Abstract
Background
Liver surgery is associated with a significant hospital stay regardless the type of liver resection. A large incision is essential for open liver surgery which is a major factor in the course of the patient’s recovery. For patients with small parenchyma liver lesions requiring surgical resection, robotic surgery potentially offers the opportunity to transform the patient’s post-operative course. A day-case robotic liver resection pathway was formulated and implemented at our institution when patients were planned for discharge within 24 h of admission for liver surgery.

Methods
Single surgeon case series of cases performed at a tertiary hepatobiliary and pancreatic centre between September 2022 and November 2023. The inclusion criteria were non-anatomical wedge resections, < 2 anatomical segmental resections, left lateral hepatectomy and minimally invasive surgery.

Results
This is the first series of robotic day-case minor liver resection in the United Kingdom. 20 patients were included in this case series. The mean operative time was 86.6 ± 30.9 min and mean console time was 58.6 ± 24.5 min. Thirteen patients (65%) were discharged within 24 h of surgery. The main cause of hospitalisation beyond 24 h was inadequate pain relief. There were no Clavien–Dindo grade III or above complications, no 30-day readmission and 90-day mortalities.

Conclusion
This case series demonstrates that robotic day-case liver resection is safe and feasible. Robust follow-up pathways must be in place to allow for the safe implementation of this approach, to monitor for any complications and to allow intervention as required in a timely manner.