bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical Role of Regulatory T Cells in Th17-Mediated Minor Antigen-Disparate Rejection
Authors: Vokaer Benoît , Van Rompaey Nicolas , Lemaître Philippe H. , Lhommé Frédéric , Kubjak Carole , Benghiat Fleur S. , Iwakura Yoichiro , Petein Michel , Field Kenneth A. , Goldman Michel , Le Moine Alain , Charbonnier Louis-Marie 
Published: August 2010

Abstract
Th17-mediated immune responses have been recently identified as novel pathogenic mechanisms in a variety of conditions; however, their importance in allograft rejection processes is still debated. In this paper, we searched for MHC or minor Ag disparate models of skin graft rejection in which Th17 immune responses might be involved. We found that T cell-derived IL-17 is critical for spontaneous rejection of minor but not major Ag-mismatched skin grafts. IL-17 neutralization was associated with a lack of neutrophil infiltration and neutrophil depletion delayed rejection, suggesting neutrophils as an effector mechanism downstream of Th17 cells. Regulatory T cells (Tregs) appeared to be involved in Th17 reactivity. We found that in vivo Treg depletion prevented IL-17 production by recipient T cells. An adoptive cotransfer of Tregs with naive monospecific antidonor T cells in lymphopenic hosts biased the immune response toward Th17. Finally, we observed that IL-6 was central for balancing Tregs and Th17 cells as demonstrated by the prevention of Th17 differentiation, the enhanced Treg/Th17 ratio, and a net impact of rejection blockade in the absence of IL-6. In conclusion, the ability of Tregs to promote the Th17/neutrophil-mediated pathway of rejection that we have described should be considered as a potential drawback of Treg-based cell therapy.
Definition of Key Variables for the Induction of Optimal NY-ESO-1–Specific T Cells in HLA Transgene Mice
Authors: Johannsen Alexandre , Genolet Raphaël , Legler Daniel F. , Luther Sanjiv A. , Luescher Immanuel F. 
Published: August 2010

AbstractAn attractive treatment of cancer consists in inducing tumor-eradicating CD8+ CTL specific for tumor-associated Ags, such as NY-ESO-1 (ESO), a strongly immunogenic cancer germ line gene-encoded tumor-associated Ag, widely expressed on diverse tumors. To establish optimal priming of ESO-specific CTL and to define critical vaccine variables and mechanisms, we used HLA-A2/DR1 H-2−/− transgenic mice and sequential immunization with immunodominant DR1- and A2-restricted ESO peptides. Immunization of mice first with the DR1-restricted ESO123–137 peptide and subsequently with mature dendritic cells (DCs) presenting this and the A2-restriced ESO157–165 epitope generated abundant, circulating, high-avidity primary and memory CD8+ T cells that efficiently killed A2/ESO157–165+ tumor cells. This prime boost regimen was superior to other vaccine regimes and required strong Th1 cell responses, copresentation of MHC class I and MHC class II peptides by the same DC, and resulted in upregulation of sphingosine 1-phosphate receptor 1, and thus egress of freshly primed CD8+ T cells from the draining lymph nodes into circulation. This well-defined system allowed detailed mechanistic analysis, which revealed that 1) the Th1 cytokines IFN-γ and IL-2 played key roles in CTL priming, namely by upregulating on naive CD8+ T cells the chemokine receptor CCR5; 2) the inflammatory chemokines CCL4 (MIP-1β) and CCL3 (MIP-1α) chemoattracted primed CD4+ T cells to mature DCs and activated, naive CD8+ T cells to DC–CD4 conjugates, respectively; and 3) blockade of these chemokines or their common receptor CCR5 ablated priming of CD8+ T cells and upregulation of sphingosine 1-phosphate receptor 1. These findings provide new opportunities for improving T cell cancer vaccines.
ChemInform Abstract: Preparation of Molybdenum‐Based Catalysts by New Slurry Impregnation Method: Active Carbon Supported Molybdenum Sulfide Hydrodesulfurization Catalyst.
Authors: ZDRAZIL M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Characterization and Crystal Structure of a New Copper Fluorocarbonate KCu(CO3)F.
Authors: MERCIER N. , LEBLANC M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Indan‐2,2‐dicarboxylic Acid, C11H10O4.
Authors: GARCIA J. G. , ENAS J. D. , FRONCZEK F. R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Reduction of α‐Keto Esters Derived from Functionalized Cholic Acid.
Authors: MAITRA U. , MATHIVANAN P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Production of Optically Active Ketones by a Palladium‐Induced Cascade Reaction from Racemic β‐Ketoesters.
Authors: ABOULHODA S. J. , HENIN F. , MUZART J. , THOREY C. , BEHNEN W. , MARTENS J. , MEHLER T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N,N‐Bis(trimethylsilyl)ynamines (I): Cycloaddition Reactions with Dimethyl Acetylenedicarboxylate and Ketenes.
Authors: SCHULTE N. , MOELLER M. H. , RODEWALD U. , WUERTHWEIN E.‐U. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Modified Synthesis of o‐Hydroxyaryl Aldehydes.
Authors: WANG R. X. , YOU X. Z. , MENG Q. J. , MINTZ E. A. , BU X. R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (1‐S) and (1‐R) cis 2‐Methylcyclopentanols Through Lipase Mediated Resolution.
Authors: REINHOLD A. R. , ROSATI R. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silver Oxide‐Assisted Palladium‐Catalyzed Cross Coupling of Methyl 2‐ Halo‐2,3‐butadienoates (I) with Arylboronic Acids (II).
Authors: GILLMANN T. , WEEBER T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthetic Route to Optically Active α‐Alkyl‐2‐ and 3‐ Furylcarbinols by Intramolecular Diastereoselectivity.
Authors: GIRODIER L. D. , ROUESSAC F. P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New Homochiral Polyfunctionalized Furan‐2(5H)‐ones.
Authors: MARTIN M. R. , MATEO A. I. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of Halogenated Spiro Bi‐2(5H)‐Furanones.
Authors: JAKUBCOVA M. , VEGH D. , KOZISEK J. , DVORSKY A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: π‐Facial Diastereoselection in (4 + 2) Cycloadditions of 3,4‐Epoxy‐ 2‐methyleneoxolanes with Oxadienes: A Short Synthesis of Spiroketals.
Authors: PALE P. , BOUQUANT J. , CHUCHE J. , CARRUPT P. A. , VOGEL P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Spirosuccinimide Aldose Reductase Inhibitors Derived from Isoquinoline‐1,3‐diones: 2‐((4‐Bromo‐2‐fluorophenyl)methyl)‐6‐ fluorospiro(isoquinoline‐4(1H),3′‐pyrrolidine)‐1,2′,3,5′(2H)‐tetrone and Congeners. Part 1.
Authors: MALAMAS M. S. , HOHMAN T. C. , MILLEN J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Phosphorylmono‐ and ‐dichloroacetaldehydes.
Authors: GUSEINOV F. I. , MOSKVA V. V. , ISMAILOV V. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 5‐Phosphorylation of 2‐Thiophenecarboxaldehyde N,N‐Dimethylhydrazone ( I).
Authors: TOLMACHEV A. A. , IVONIN S. P. , KHARCHENKO A. V. , KOZLOV E. S. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structures of Five New Highly Oxygenated Labdane‐Type Diterpenoids, Ptychantins A‐E, Closely Related to Forskolin from the Liverwort Ptychanthus striatus.
Authors: HASHIMOTO T. , HORIE M. , TOYOTA M. , TAIRA Z. , TAKEDA R. , TORI M. , ASAKAWA Y. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Potent Prolyl Endopeptidase Inhibitors: Synthesis and Structure‐ Activity Relationships of Indan and Tetralin Derivatives and Their Analogues.
Authors: TANAKA Y. , NIWA S. , NISHIOKA H. , YAMANAKA T. , TORIZUKA M. , YOSHINAGA K. , KOBAYASHI N. , IKEDA Y. , ARAI H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regio‐ and Diastereoselective Lipase‐Catalyzed Preparation of Acetylated 2‐O‐Glucosylglycerols.
Authors: COLOMBO D. , RONCHETTI F. , SCALA A. , TAINO I. M. , MARINONE ALBINI F. , TOMA L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Highly Convergent Synthesis of the Lewisy Blood Group Determinant in Conjugatable Form.
Authors: BEHAR V. , DANISHEFSKY S. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Enantiomerically Pure Cyclopropyl Carbocyclic Nucleosides.
Authors: ZHAO Y. , YANG T.‐F. , LEE M. , CHUN B. K. , DU J. , SCHINAZI R. F. , LEE D. , NEWTON M. G. , CHU C. K. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hepoxilins B3: Synthesis of All Four Stereoisomers and a Glutathione Adduct.
Authors: BELOSLUDTSEV YU. Y. , KOLLAH R. O. , FALCK J. R. , CAPDEVILA J. H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Stereochemical Manipulations of the Penicillin Nucleus.
Authors: BALDWIN J. E. , CHAN R. Y. , SUTHERLAND J. D. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Enantioselective Macrolide Synthesis. Part 2. Use of Differential Deprotection Protocols.
Authors: JONES G. B. , CHAPMAN B. J. , HUBER R. S. , BEATY R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Copper‐Mediated Nitrogen Ligand Oxidation and Oxygenation
Authors: SAYRE L. M. , TANG W. , REDDY K. V. , NADKARNI D. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidation Catalysis: A Binuclear Approach
Authors: FERINGA B. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Angular Dependence of Dipolar Substituent Effects.
Authors: BOWDEN K. , GRUBBS E. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Peptidyl‐Prolyl cis/trans Isomerases and Their Effectors
Authors: FISCHER G. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Atomic Force Microscopy in the Photochemistry of Chalcones
Authors: KAUPP G. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spectroscopic Studies of Radical Ions in Polyatomic Matrixes
Authors: SHIDA T. , KATO T. , MOMOSE T. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optical Absorption Spectra of Au7, Au9, Au11, and Au13, and Their Cations: Gold Clusters with 6, 7, 8, 9, 10, 11, 12, and 13 s‐Electrons
Authors: COLLINGS B. A. , ATHANASSENAS K. , LACOMBE D. , RAYNER D. M. , HACKETT P. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Moessbauer‐Investigation of Ferrimagnetic Spinels in the System CdxNi1‐ xFe2O4.
Authors: RIEDEL E. , PRICK D. , WOLSKA E. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Effect of Additives on Lithium Cycling Efficiency.
Authors: HIRAI T. , YOSHIMATSU I. , YAMAKI J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrochemical Oxidation of Manganese(II) in HClO4 Solutions.
Authors: ZHANG H. , PARK S.‐M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of an Active and Very Selective Iron‐Molybdenum Catalyst for Methanol Oxidation.
Authors: IVANOV K. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Temperature Catalytic Reduction of Nitrogen Monoxide by Carbon Monoxide and Hydrogen Over La1‐xSrxMO3 Perovskites (M: Fe, Co) During Reducing and Oxidising Conditions.
Authors: LINDSTEDT A. , STROEMBERG D. , MILH M. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Donor‐Stabilized Aluminum(I) Bromide.
Authors: MOCKER M. , ROBL C. , SCHNOECKEL H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Extrusion of Molecular Clusters from Solid‐State Materials: Synthesis by Application of γ‐Irradiation. Molecular and Crystal Structure of (H9O4)(Et4N)(Mo3S7Br6).
Authors: FEDIN V. P. , MUELLER A. , FILIPEK K. , ROHLFING R. , BOEGGE H. , VIROVETS A. V. , DZIEGIELEWSKI J. O. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Crystal Structure of Cu0.25Ho1.25W2O8.
Authors: SZILLAT H. , MUELLER‐BUSCHBAUM HK. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Formation of Quaternary Centers Through Aza‐Annulation of Chiral β‐Enamino Esters with Acrylate Derivatives.
Authors: BARTA N. S. , BRODE A. , STILLE J. R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.