bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A Noble‐Metalate Bowl: The Polyoxo‐6‐vanado(V)‐7‐palladate(II) [Pd7V6O24(OH)2]6‐.
Authors: Izarova Natalya V. , Vankova Nina , Banerjee Abhishek , Jameson Geoffrey B. , Heine Thomas , Schinle Florian , Hampe Oliver , Kortz Ulrich 
Published: December 2010

AbstractThe new polyoxometalate (IV) crystallizes in the monoclinic space group P21/n with Z = 4 (single crystal XRD).
ChemInform Abstract: Catalyst versus Substrate Induced Selectivity: Kinetic Resolution by Palladacycle Catalyzed Allylic Imidate Rearrangements.
Authors: Peters Rene , Xin Zhuo‐qun , Maier Frank 
Published: December 2010

AbstractThe first kinetic resolution of allylic trifluoroacetimidates is achieved by using planar chiral palladacycles as catalysts.
ChemInform Abstract: Asymmetric Formal trans‐Dihydroxylation and trans‐Aminohydroxylation of α,β‐Unsaturated Aldehydes via an Organocatalytic Reaction Cascade.
Authors: Albrecht Lukasz , Jiang Hao , Dickmeiss Gustav , Gschwend Bjoern , Hansen Signe Grann , Joergensen Karl Anker 
Published: December 2010

AbstractA highly enantio‐ and diastereoselective, organocatalytic one‐pot formal trans‐dihydroxylation and trans‐aminohydroxylation of α,β‐unsaturated aldehydes is developed.
ChemInform Abstract: Palladium‐Catalyzed Dimerization of Vinyl Ethers to Acetals.
Authors: Chen Changle , Jordan Richard F. 
Published: December 2010

AbstractThe dinuclear dicationic complex (I) catalyzes the dimerization of alkyl or silyl vinyl ethers to acetals as well as the cyclization of divinyl ethers to cyclic acetals.
ChemInform Abstract: Zinc(II) Containing γ‐Keggin Sandwich‐Type Silicotungstate: Synthesis in Organic Media and Oxidation Catalysis.
Authors: Kikukawa Yuji , Yamaguchi Kazuya , Mizuno Noritaka 
Published: December 2010

AbstractReaction of a polyoxymetalate with Zn(acac)2 provides access towards a novel γ‐Keggin zinc‐containing sandwich‐type polyoxymetalate.
ChemInform Abstract: Regioselective Ring Cleavage of Phenyl‐ or/and Alkyl‐Substituted Epoxides with Al‐Trifluoromethanesulfonyldiisobutylalane. Comparison of Its Reactivity with Al‐Methanesulfonyldiisobutylalane.
Authors: Cha Jin Soon , Park Seung Jin 
Published: December 2010

AbstractEpoxides are cleaved with complete regioselectivity in the presence of Al‐trifluoromethanesulfonyldiisobutylalane.
ChemInform Abstract: Ethynyl‐1,2‐benziodoxol‐3(1H)‐one (EBX): An Exceptional Reagent for the Ethynylation of Keto, Cyano, and Nitro Esters.
Authors: Fernandez Gonzalez Davinia , Brand Jonathan P. , Waser Jerome 
Published: December 2010

AbstractIn situ desilylation of reagent (II) generates a highly reactive ethynylation species which is successfully applied in the acetylene transfer towards various cyclic and acyclic keto, cyano and nitro esters.
ChemInform Abstract: Palladium‐Catalyzed Hydroarylation of 1,3‐Dienes with Boronic Esters via Reductive Formation of π‐Allyl Palladium Intermediates under Oxidative Conditions.
Authors: Liao Longyan , Sigman Matthew S. 
Published: December 2010

AbstractHigh selectivity, that has steric origin, is observed for the 1,2‐addition products and is shown to have a steric origin.
ChemInform Abstract: Practical New Silyloxy‐Based Alkyne Metathesis Catalysts with Optimized Activity and Selectivity Profiles.
Authors: Heppekausen Johannes , Stade Robert , Goddard Richard , Fuerstner Alois 
Published: December 2010

AbstractModified Schrock catalysts (I)(fully air‐stable and user‐friendly), (II)(air‐sensitive but highly active and selective) and (III)(similar potent as the etherate; can be handled in air but needs to be stored under argon) are prepared and tested under optimized conditions A)‐C).
ChemInform Abstract: Rapid and Slow Generation of 1‐Trifluoromethylvinyllithium: Syntheses and Applications of CF3‐Containing Allylic Alcohols, Allylic Amines, and Vinyl Ketones.
Authors: Nadano Ryo , Fuchibe Kohei , Ikeda Masahiro , Takahashi Hiroki , Ichikawa Junji 
Published: December 2010

AbstractTwo protocols are developed for the synthesis of (trifluoromethyl)vinyl compounds by rapid and slow lithium halogen exchange processes generating thermally unstable vinyllithium compounds.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular Carboacetoxylation of 4‐Pentenyl‐Substituted Malonate Esters with Iodobenzene Diacetate.
Authors: Fujino Daishi , Yorimitsu Hideki , Oshima Koichiro 
Published: December 2010

AbstractA novel route to cyclopentane derivatives is presented using the palladium‐catalyzed intramolecular carboacetoxylation of 4‐pentenyl‐substituted malonate esters.
ChemInform Abstract: Stereocontrolled Synthesis of Spiro[n.2]alkenes by Ring Contraction of Fused‐Cyclobutanols.
Authors: Takasu Kiyosei , Nagamoto Yuuki , Takemoto Yoshiji 
Published: December 2010

AbstractThe present newly developed unusual ring contraction rearrangement leads to spirocyclopropanes from fused cyclobutanols.
ChemInform Abstract: Heterogeneous Aromatic Amination of Aryl Halides with Arylamines in Water with PS‐PEG Resin‐Supported Palladium Complexes.
Authors: Hirai Yoshinori , Uozumi Yasuhiro 
Published: December 2010

AbstractCatalytic amination of aryl bromides with primary amines is achieved in water under heterogeneous conditions in the presence of a palladium catalyst which is anchored to the amphiphilic PS‐PEG resin to provide a series of triarylamines without metal‐contamination.
ChemInform Abstract: A Facile Protocol for the Synthesis of Mono‐N‐methyl Anilines via Formimidate Intermediates.
Authors: Sun Nan , Wang Shuai , Mo Weimin , Hu Baoxiang , Shen Zhenlu , Hu Xinquan 
Published: December 2010

AbstractThe efficient and environmentally benign method for preparation of N‐methyl anilines relies on NaBH3(O—Ac) reduction of formimidate intermediates quantitatively generated from anilines and triethyl orthoformate.
ChemInform Abstract: Enantioselective Nickel‐Catalyzed Reductive Coupling of Alkynes and Imines.
Authors: Zhou Chang‐Yue , Zhu Shou‐Fei , Wang Li‐Xin , Zhou Qi‐Lin 
Published: December 2010

AbstractGood to excellent yields are obtained if imines resulting from aromatic aldehydes are used.
ChemInform Abstract: Organocatalytic Approach to (S)‐1‐Arylpropan‐2‐ols: Enantioselective Synthesis of the Key Intermediate of Antiepileptic Agent (‐)‐Talampanel.
Authors: Sawant Rajiv T. , Waghmode Suresh B. 
Published: December 2010

AbstractKey step in the synthesis of title compounds (III) is the asymmetric α‐aminoxylation of aldehydes (I).
ChemInform Abstract: In situ Hydrogen from Aqueous‐Methanol for Nitroarene Reduction and Imine Formation over an Au—Pd/Al2O3 Catalyst.
Authors: Xiang Yizhi , Meng Qiangqiang , Li Xiaonian , Wang Jianguo 
Published: December 2010

AbstractThe direct synthesis of imines (III) from nitroarenes (II) and aldehydes (I) is realized over an Au‐Pd/Al2O3 catalyst in the presence of MeOH.
ChemInform Abstract: Synthesis of Dienamides via the Reaction of Nitrile with Allylindium Reagents and Intramolecular Acyl Group Quenching Cascade.
Authors: Kim Sung Hwan , Kim Yu Mi , Kim Jae Nyoung 
Published: December 2010

AbstractA series of dienamides of type (III)—(V) or (VIII)—(X) are prepared via the reaction of nitriles with allylindium reagents.
ChemInform Abstract: First Sequential Mukaiyama—Michael Reaction/Crossed‐Claisen Condensation Using Two Molar Ketene Silyl Acetals and One Molar α,β‐Unsaturated Esters Promoted by a NaOH Catalyst.
Authors: Tamagaki Hiroaki , Nawate Yuuya , Nagase Ryohei , Tanabe Yoo 
Published: December 2010

AbstractA sequential Mukaiyama—Michael reaction and regioselective crossed‐Claisen condensation to afford 1,3,7‐tricarbonyl scaffolds is developed using two equivalents of ketene silyl acetals (II)/(IV) and one equivalent α,β‐unsaturated esters (I) in either a stepwise or one‐pot procedure.
ChemInform Abstract: Facile, Efficient, and Catalyst‐Free Electrophilic Aminoalkoxylation of Olefins: Scope and Application.
Authors: Zhou Ling , Tan Chong Kiat , Zhou Jing , Yeung Ying‐Yeung 
Published: December 2010

AbstractThe multicomponent reaction of an olefin, a cyclic ether, an sulfonamide and NBS affords a range of amino ether derivatives.
ChemInform Abstract: A New and Practical Grignard‐Coupling—Fluorination Sequence: Synthesis of 2‐Aryl Fluoroarenes.
Authors: Anbarasan Pazhamalai , Neumann Helfried , Beller Matthias 
Published: December 2010

AbstractA new method for the synthesis of 2‐aryl‐fluoroarenes is developed using an intermolecular domino Grignard coupling—fluorination sequence from aryl bromides (I) and 1,2‐dihaloarenes (II) and (IV).
ChemInform Abstract: Catalytic Asymmetric Bromoamination of Chalcones: Highly Efficient Synthesis of Chiral α‐Bromo‐β‐amino Ketone Derivatives.
Authors: Cai Yunfei , Liu Xiaohua , Hui Yonghai , Jiang Jun , Wang Wentao , Chen Weiliang , Lin Lili , Feng Xiaoming 
Published: December 2010

AbstractTitle reaction proceeds with excellent regio‐ and stereoselectivities in the presence of a chiral N,N′‐dioxide—Sb(III) catalyst.
ChemInform Abstract: Base‐Catalyzed Stereoselective Vinylation of Ketones with Arylacetylenes: A New C(sp3)—C(sp2) Bond‐Forming Reaction.
Authors: Trofimov Boris A. , Schmidt Elena Yu. , Ushakov Igor' A. , Zorina Nadezhda V. , Skital'tseva Elena V. , Protsuk Nadezhda I. , Mikhaleva Al'bina I. 
Published: December 2010

AbstractThe present new C‐vinylation of alkyl (het)aryl ketones with arylacetylenes to give 1,4‐disubstituted 3‐buten‐1‐ones proceeds with complete E‐stereoselectivity using KOH as base.
ChemInform Abstract: Stereocontrolled Synthesis of Quaternary Cyclopropyl Esters.
Authors: Bray Christopher D. , Minicone Fabrizio 
Published: December 2010

AbstractQuaternary cyclopropyl esters (III) and (V) are formed in high yields using the Wadsworth‐Emmons cyclopropanation from epoxides (I) and (IV) and substituted phosphonoacetates (II).
ChemInform Abstract: Olefin Epoxidation by Hydrogen Peroxide Catalyzed by Molybdenum Complexes in Ionic Liquids and Structural Characterization of the Proposed Intermediate Dioxoperoxomolybdenum Species.
Authors: Herbert Matthew , Alvarez Eleuterio , Cole‐Hamilton David J. , Montilla Francisco , Galindo Agustin 
Published: December 2010

AbstractThe oxodiperoxomolybdenum‐catalyzed epoxidation of cis‐cyclooctene (I) proceeds most efficiently in ionic liquid in the presence of DMPZ as base additive.
ChemInform Abstract: Palladium‐Catalyzed Cascade Aryl Addition/Intramolecular Lactonization of Phthalaldehyde to Access 3‐Aryl‐ and Alkenylphthalides.
Authors: Ye Zhishi , Qian Pengcheng , Lv Guanglei , Luo Fang , Cheng Jiang 
Published: December 2010

AbstractIt is found that PdCl2 in combination with the phosphine efficiently promotes the sequence to give 3‐arylphthalides.
ChemInform Abstract: E,E‐Bis(Styryl)Sulfones — Synthons for a New Class of Bis(heterocycles).
Authors: Padmavathi Venkatapuram , Reddy Boggu Jagan Mohan , Mahesh Konda , Thriveni Pinnu , Padmaja Adivireddy 
Published: December 2010

AbstractA new class of sulfone‐linked bis(heterocycles) having two different heterocyclic rings is synthesized.
ChemInform Abstract: Copper‐Catalyzed Intramolecular C—H Oxidation/Acylation of Formyl‐N‐arylformamides Leading to Indoline‐2,3‐diones.
Authors: Tang Bo‐Xiao , Song Ren‐Jie , Wu Cui‐Yan , Liu Yu , Zhou Ming‐Bo , Wei Wen‐Ting , Deng Guo‐Bo , Yin Du‐Lin , Li Jin‐Heng 
Published: December 2010

AbstractThe first example of the synthesis of indoline‐2,3‐diones using a transition‐metal‐catalyzed process is presented.
ChemInform Abstract: Pd‐Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Broensted Acids.
Authors: Wang Duo‐Sheng , Chen Qing‐An , Li Wei , Yu Chang‐Bin , Zhou Yong‐Gui , Zhang Xumu 
Published: December 2010

AbstractThe present method provides an efficient route to enantioenriched 2‐substituted and 2,3‐disubstituted indolines.
ChemInform Abstract: An Efficient One‐Pot Synthesis of N‐(1,3‐Diphenyl‐1H‐pyrazol‐5‐yl)amides.
Authors: Su Wei‐Nien , Lin Tsung‐Ping , Cheng Kaung‐Min , Sung Kuan‐Chin , Lin Shao‐Kai , Wong Fung Fuh 
Published: December 2010

AbstractThe advantage of the presented one‐pot method is primarily a simple work‐up procedure without isolation and purification of the intermediate 5‐amino‐1,3‐diphenyl‐pyrazole.
ChemInform Abstract: Synthesis, Crystal Structure, and Fungicidal Activity of Novel 1,5‐Diaryl‐1H‐pyrazol‐3‐oxyacetate Derivatives.
Authors: Liu Yuanyuan , Shi Hong , Li Yufeng , Zhu Hongjun 
Published: December 2010

AbstractThe fungicidal (Gibberella zeae, Rhizoctonia cerealis) activity of a series of novel pyrazole derivatives (VI) is reported.
ChemInform Abstract: Palladium‐Catalyzed Asymmetric Allylic Alkylation of 2‐Acylimidazoles as Ester Enolate Equivalents.
Authors: Trost Barry M. , Lehr Konrad , Michaelis David J. , Xu Jiayi , Buckl Andreas K. 
Published: December 2010

AbstractIn contrast to previously reported methods, the catalytic asymmetric alkylation methodology presented herein is quite general in scope for both the allylic electrophile and enolate nucleophile.
ChemInform Abstract: Towards Molecular Diversity: Dealkylation of tert‐Butyl Amine in Ugi‐Type Multicomponent Reaction Product Establishes tert‐Butyl Isocyanide as a Useful Convertible Isonitrile.
Authors: Guchhait Sankar K. , Madaan Chetna 
Published: December 2010

AbstractThe dealkylation of an alkylamine, in situ generated during Ugi reaction with tert‐butyl isonitrile (III), is smoothly achieved by microwave‐assisted reaction with HBF4 to afford the free amine [cf.
ChemInform Abstract: Copper‐Catalyzed Cascade Approach to 1,3‐Diazabicyclo[3.1.0]hex‐3‐enes from Aziridines and Ethyl Diazoacetate.
Authors: Zhu Yuanxun , Wang Shaoyin , Wen Shan , Lu Ping , Wang Yanguang 
Published: December 2010

AbstractThe procedure offers a novel synthesis of diazabicyclohexanes (III).
ChemInform Abstract: Synthesis of 5‐Amino‐oxazole‐4‐carboxylates from α‐Chloroglycinates.
Authors: Zhang Jianmin , Coqueron Pierre‐Yves , Vors Jean‐Pierre , Ciufolini Marco A. 
Published: December 2010

AbstractCondensation of α‐chloroglycinates with isonitriles (II) or Et2AlCN gives 5‐amino‐oxazoles in moderate yields.
ChemInform Abstract: Synthesis of Isomeric 2,3,5‐Trisubstituted Perhydropyrrolo[3,4‐d]isoxazole‐4,6‐diones via 1,3‐Dipolar Cycloaddition Reactions.
Authors: Oezkan Hamdi , Yildirir Yilmaz 
Published: December 2010

AbstractCycloaddition of nitrones (I) to maleimides (II) produces a diastereomeric couple of a new type of isoxazolidine derivatives.
ChemInform Abstract: Synthesis and Biological Evaluation of New Naphthoquinone‐Containing Pyrrolo‐Thiazoles as Anticancer Agents.
Authors: Lopes Susana M. M. , Laranjo Mafalda , Serra Armenio C. , Abrantes Ana Margarida , Rocha Gonsalves Antonio M. d'A. , Botelho Maria Filomena , Beja Ana Matos , Silva Manuela Ramos , Pindho e Melo Teresa M. V. D. 
Published: December 2010

AbstractNaphthoquinones undergo 1,3‐dipolar cycloaddition with bicyclic mnchnones generated from thiazolidines affording new pyrrolo‐thiazoles with a fused quinone nucleus.
ChemInform Abstract: Rhodium‐Catalyzed Synthesis of γ‐Pyrones by Three Consecutive Redox‐Aldol Reactions of Allylic Alcohols with α,β‐Unsaturated Aldehydes.
Authors: Mizuno Akio , Kusama Hiroyuki , Iwasawa Nobuharu 
Published: December 2010

AbstractThe present new method for the synthesis of γ‐pyrones involves a novel rhodium‐catalyzed tandem redox—aldol reaction of allylic alcohols with α,β‐unsaturated aldehydes.
ChemInform Abstract: Asymmetric Synthesis of 4‐Amino‐4H‐chromenes by Organocatalytic Oxa‐Michael/Aza‐Baylis—Hillman Tandem Reactions.
Authors: Aleman Jose , Nunez Alberto , Marzo Leyre , Marcos Vanesa , Alvarado Cuauhtemoc , Garcia Ruano Jose Luis 
Published: December 2010

AbstractTitle tandem reaction proceeds under mild conditions using as low as 5 mol% of prolinol‐derived organocatalyst to give the aminochromenes (III), (V) in excellent enantioselectivities (up to 99% e.e.).
ChemInform Abstract: An Expeditious Oxidative Aromatization of Hantzsch 1,4‐Dihydropyridines to Pyridines Using Cetyltrimethylammonium Peroxodisulfate: A Phase Transferring Oxidant.
Authors: Kumar Parvin , Kumar Ashwani 
Published: December 2010

AbstractThe title oxidant is an efficient, stable and cheap reagent which is soluble in most organic solvents.
ChemInform Abstract: Microwave‐Assisted Copper(II)‐Catalyzed One‐Pot Four‐Component Synthesis of Multifunctionalized Dihydropyridines.
Authors: Pasunooti Kalyan Kumar , Jensen Chantel Nixon , Chai Hua , Leow Min Li , Zhang Da‐Wei , Liu Xue‐Wei 
Published: December 2010

AbstractA library of hexahydroquinolines of type (IV) is prepared from cyclohexadiones, a wide variety of aromatic, heteroaromatic or aliphatic aldehydes, keto esters, and ammonium acetate in the presence of only 2 mol% of cupric triflate (48 examples).
ChemInform Abstract: The Design of Efficient and Selective Routes to Pyridyl Analogues of 2,3‐Dihydro‐1,4‐benzodioxin‐6‐carbaldehyde.
Authors: Barfoot Christopher W. , Brown Pamela , Dabbs Steven , Davies David T. , Hennessy Alan J. , Miles Timothy J. , Pearson Neil D. 
Published: December 2010

AbstractSix routes starting from commercially available kojic acid allow the preparation of pyridyl aldehydes (I)‐(VI), which may be of interest as antibacterial drugs.
ChemInform Abstract: A Versatile Route to 3‐(Pyrimidin‐4‐yl)‐imidazo[1,2‐a]pyridines and 3‐(Pyrimidin‐4‐yl)‐pyrazolo[1,5‐a]pyridines.
Authors: Ducray Richard , et al. et al. 
Published: December 2010

AbstractA two‐step synthesis of imidazopyridines (V) involves formation of vinyl ethers via phosphine‐free Heck reaction and subsequent cyclocondensation with aminopyridines.
ChemInform Abstract: Facile Method for the Combinatorial Synthesis of 2,2‐Disubstituted Quinazolin‐4(1H)‐one Derivatives Catalyzed by Iodine in Ionic Liquids.
Authors: Wang Xiang‐Shan , Yang Ke , Zhou Jie , Tu Shu‐Jiang 
Published: December 2010

Abstract2‐Aminobenzamides and aliphatic, aromatic, cyclic, and heterocyclic ketones as well as cyclohexane‐1,4‐diones give the desired quinazolinones in high yields (73 examples).
ChemInform Abstract: Convenient Synthesis of Substituted 2‐(2‐Iminocoumarin‐3‐yl)thieno[2,3‐d]pyrimidin‐4‐ones.
Authors: Shynkarenko Pavlo E. , Vlasov Sergiy V. , Kovalenko Sergiy M. , Shishkina Svitlana V. , Shishkin Oleg V. , Chernykh Valentin P. 
Published: December 2010

AbstractIntermediates (III) are isolable solids which are used without purification for the following thermal rearrangement.
ChemInform Abstract: Synthesis of Novel 8,9‐Dihydro‐5H‐pyrimido[4,5‐e][1,4]diazepin‐7(6H)‐ones.
Authors: Xiang Jinbao , Wen Dongsheng , Xie Hongxiang , Dang Qun , Bai Xu 
Published: December 2010

AbstractBis‐electrophilic pyrimidines such as (I), (VII), (X), and (XII) and aliphatic or aromatic amines or ammonia give the title diazepine derivatives bearing a 4‐chloro substituent (25 examples).
ChemInform Abstract: Chrysophaentins A—H, Antibacterial Bisdiarylbutene Macrocycles that Inhibit the Bacterial Cell Division Protein FtsZ.
Authors: Plaza Alberto , Keffer Jessica L. , Bifulco Giuseppe , Lloyd John R. , Bewley Carole A. 
Published: December 2010

AbstractBiological, biochemical, and structural studies presented in this paper show Chrysophaentin A (Ia) is the most potent of the isolated antibiotics, inhibited the growth of clinically relevant Gram‐positive bacteria including methicillin‐resistant Staphylococcus aureus, multidrug‐resistant S.
ChemInform Abstract: Iridium‐Catalyzed anti‐Diastereo‐ and Enantioselective Carbonyl (Trimethylsilyl)allylation from the Alcohol or Aldehyde Oxidation Level.
Authors: Han Soo Bong , Gao Xin , Krische Michael J. 
Published: December 2010

AbstractA highly anti‐diastereo‐ and enantioselective (trimethylsilyl)allylation of aldehydes and alcohols is reported.
ChemInform Abstract: Base‐Accelerated Enantioselective Substitution of Morita—Baylis—Hillman Carbonates with Dialkyl Phosphine Oxides.
Authors: Sun Wangsheng , Hong Liang , Liu Chunxia , Wang Rui 
Published: December 2010

AbstractOptimized reaction conditions including catalytic quinidine and sodium carbonate to activate nonreactive phosphine oxides are developed.
ChemInform Abstract: Camellisins A‐C, Three New Triterpenoids from the Roots of Camellia sinensis
Authors: Lei Chun , Hu Zhuo , Pu Jian‐Xin , Wang Yuan‐Yuan , Xiao Wei‐Lie , Gong Ning‐Bo , Li Yan , Lu Yang , Zheng Qi‐Tai , Sun Han‐Dong 
Published: December 2010

Abstractstructure and cytotoxicity
ChemInform Abstract: Reactivity Difference Between Protolytic Forms of Some Macrocyclic Chromium(III) Complexes in Ligand Substitution and Electron Transfer Processes
Authors: Katafias Anna , Chatlas Janusz , Impert Olga , Kita Przemyslaw , Madej Edyta , Topolski Adrian , Wrzeszcz Grzegorz , Eriksen Jette , Monsted Ole , Mills Andrew 
Published: December 2010

AbstractReview: 70 refs.
ChemInform Abstract: Modification of Nucleic Acids Using [3 + 2]‐Dipolar Cycloaddition of Azides and Alkynes
Authors: Ustinov A. V. , Stepanova I. A. , Dubnyakova V. V. , Zatsepin T. S. , Nozhevnikova E. V. , Korshun V. A. 
Published: December 2010

AbstractReview: 336 refs.
ChemInform Abstract: Towards a Green Molecular Chemistry
Authors: Campagne Jean‐Marc , Agbossou Francine , Ayad Tahar , Baudoin Olivier , Buono Gerard , Chataigner Isabelle , Crevisy Christophe , Dez Isabelle , Donnard Morgan , Fache Fabienne , et al. et al. 
Published: December 2010

AbstractReview: 75 refs.
Mikrobielle Herstellung von 1, 3‐Propandiol. Fermentative Biotechnologie
Authors: Steverding Dietmar 
Published: December 2010

AbstractDie mikrobielle Herstellung von 1,3‐Propandiol ist eine Erfolgsgeschichte für die moderne Biotechnologie. Ehemals eine Spezialchemikalie ist 1,3‐Propandiol binnen weniger Jahren zu einer Massenchemikalie aufgestiegen. Das Interesse an 1,3‐Propandiol als neuem Massenprodukt ist seiner Verwendung als Ausgangsmaterial für neuartige Kunststoffe mit hervorragenden physikalischen und chemischen Eigenschaften zu verdanken. Erst mit der Einführung eines neuen biotechnologischen Produktionsverfahrens konnte 1,3‐Propandiol aus erneuerbaren Rohstoffen mithilfe von gentechnisch veränderten E.‐coli‐Bakterien konkurrenzfähig hergestellt werden. Die Entwicklung des rekombinanten E.‐coli‐Stamms dauerte über 7 Jahre und 36 Gene mussten verändert werden, damit die Bakterien das 1,3‐Propandiol produzieren konnten. Auch könnte die Umwandlung von Glycerin zu 1,3‐Propandiol die Lösung des Glycerinproblems bei der Biodieselherstellung sein.
Das Geheimnis des Weihnachtsdufts. Von Anisplätzchen bis Zimtstern
Authors: Roth Klaus 
Published: December 2010

AbstractFür viele von uns hat sich der köstliche Duft von frisch gebackenen Weihnachtskeksen seit unserer Kindheit fest in unser Gedächtnis eingeprägt. Die traditionellen Rezepte mögen sich in vielen Ländern voneinander unterscheiden, aber meist basieren sie auf einigen typischen Gewürzen: Anis, Kardamom, Muskat, Nelken, Piment, Vanille und Zimt. Da der Geruchssinn ein chemischer Sinn ist, lohnt eine tiefere Betrachtung der Strukturen und der Biosynthese der sehr aromatischen Duftstoffe. Dies steigert noch die Freude an unseren Weihnachtskeksen.
Wenn Kälte flüssig macht
Authors: Schöll Achim 
Published: December 2010

AbstractJeden Winter ist es gut zu beobachten: Wird flüssiges Wasser abgekühlt, so verwandelt es sich in kristallines Eis. Am Gefrierpunkt ändert sich der Aggregatzustand des Wassers, und während sich die Moleküle in der Flüssigkeit ungeordnet bewegen, ordnen sie sich im Festkörper zu einem regelmäßigen Gitter an. In seltenen Fällen kann dieser Prozess allerdings auch umgekehrt ablaufen: Dann wird aus dem geordneten Festkörper bei sinkenden Temperaturen eine Flüssigkeit, was den üblichen Erfahrungen völlig widerspricht. Physiker nennen diesen Effekt “inverses Schmelzen”. Allerdings sind dafür in der Regel extreme physikalische Bedingungen erforderlich: Der Druck muss meist sehr hoch sein oder die Temperatur dicht am absoluten Nullpunkt liegen. Nun wurde dieses inverse Schmelzen erstmals an einem zweidimensionalen System aus organischen Molekülen ohne zusätzlichen äußeren Druck nachgewiesen.