bluuebunny/crossref_metadata_2025_split huggingface dataset:
The performance gap in UK property returns
Authors: Lee Stephen 
Published: July 2012

PurposeWhen one talks of the return performance one typically refers to an average buy‐and‐hold return, also known as time‐weighted return. However, the returns of investors can be quite different. Investor returns are determined not only by the returns on the underlying assets but also by the timing and magnitude of their capital flows into and out of these assets. To account for the annual‐to‐annual variation in assets under management, a dollar‐weighted return has to be calculated. The difference between time‐weighted returns and dollar‐weighted returns is known as the performance gap. The purpose of this paper will be to investigate this in the UK property market.Design/methodology/approachUsing an approach similar to that of Dichev the authors examine the performance gap in the UK direct property market using historical return data for 45 market‐segments over the time period 1981‐2009.FindingsThe results show that the performance gap was negative, i.e. investor returns were greater than asset returns. That is, UK direct property investors have shown greater returns than their underlying investments. This implies that estimates of the performance of the UK property market based on property returns do not reflect the experience of investors as a group.Originality/valueThis study provides the first evidence of the performance gap in the UK direct real estate market.
Flow cytometry technique for analysing Leishmania promastigote phagocytosis by human polymorphonuclear leucocytes and monocytes
Authors: REBBESTAD K. , HERREDSVELA S. , SORNES S. , EIDE G. E. , MÜLLER K. E. , SPRIET E. , SJURSEN H. , NAESS A. 
Published: July 2012

SummaryIn this study, we developed a flow cytometry technique for studying Leishmania (L.) mexicana phagocytosis by human polymorphonuclear leucocytes (PMNs) and monocytes. Leishmania promastigotes are elongated in shape and flagellated. This influences the light scatter when phagocytosis is measured by flow cytometry. Accordingly, we developed an oxidative burst method for measuring the phagocytic process. As this is an indirect marker of phagocytosis, we used confocal, light and electron microscopy to verify that promastigotes were, indeed, internalized by the phagocytes. For both PMNs and monocytes, the optimal conditions for achieving high sensitivity in flow cytometry detection were 5% pooled human serum and 15 min. incubation time. Incubations at 35, 37 and 39°C were also equally efficient for both PMNs and monocytes. Optimal parasite ratios were 10 parasites per PMN and 20 parasites per monocyte. Under these conditions, Leishmania were readily phagocytosed by human PMNs and monocytes and the effects of other influences, such as treatment, would be readily detectable. This indicated that these cells may play a role in the immune response against Leishmania.
Pyrosequencing Analysis of Bacterial Diversity in 14 Wastewater Treatment Systems in China
Authors: Wang Xiaohui , Hu Man , Xia Yu , Wen Xianghua , Ding Kun 
Published: July 2012

ABSTRACT

To determine if there is a core microbial community in the microbial populations of different wastewater treatment plants (WWTPs) and to investigate the effects of wastewater characteristics, operational parameters, and geographic locations on microbial communities, activated sludge samples were collected from 14 wastewater treatment systems located in 4 cities in China. High-throughput pyrosequencing was used to examine the 16S rRNA genes of bacteria in the wastewater treatment systems. Our results showed that there were 60 genera of bacterial populations commonly shared by all 14 samples, including
Ferruginibacter
,
Prosthecobacter
,
Zoogloea
, Subdivision 3 genera
incertae sedis
, Gp4, Gp6, etc., indicating that there is a core microbial community in the microbial populations of WWTPs at different geographic locations. The canonical correspondence analysis (CCA) results showed that the bacterial community variance correlated most strongly with water temperature, conductivity, pH, and dissolved oxygen (DO) content. Variance partitioning analyses suggested that wastewater characteristics had the greatest contribution to the bacterial community variance, explaining 25.7% of the variance of bacterial communities independently, followed by operational parameters (23.9%) and geographic location (14.7%). Results of this study provided insights into the bacterial community structure and diversity in geographically distributed WWTPs and discerned the relationships between bacterial community and environmental variables in WWTPs.
Complete Genome Sequence of the Opportunistic Food-Borne Pathogen Cronobacter sakazakii ES15
Authors: Shin Hakdong , Lee Ju-Hoon , Choi Younho , Ryu Sangryeol 
Published: July 2012

ABSTRACT

Cronobacter sakazakii
is an emerging pathogen associated with several outbreaks of food-borne illness in premature infants. To characterize its physiology and pathogenicity at the molecular level,
C. sakazakii
ES15 was isolated and its genome was completely sequenced and analyzed. Here, the results are announced and major findings from its annotation data are reported.
Complete Genome Sequence of the Hyperthermophilic Cellulolytic Crenarchaeon “Thermogladius cellulolyticus” 1633
Authors: Mardanov Andrey V. , Kochetkova Tatiana V. , Beletsky Alexey V. , Bonch-Osmolovskaya Elizaveta A. , Ravin Nikolai V. , Skryabin Konstantin G. 
Published: July 2012

ABSTRACT

Strain 1633, a novel member of the genus
Thermogladius
, isolated from a freshwater hot spring, is an anaerobic hyperthermophilic crenarchaeon capable of fermenting proteinaceous and cellulose substrates. The complete genome sequence reveals genes for protein and carbohydrate-active enzymes, the Embden-Meyerhof pathway for glucose metabolism, cytoplasmic NADP-dependent hydrogenase, and several energy-coupling membrane-bound oxidoreductases.
In Vitro
Intragenomic Rearrangement of Porcine Circovirus Type 2
Authors: Wen Libin , He Kongwang , Ni Yanxiu , Zhang Xuehan , Li Bin , Wang Xiaomin , Guo Rong li , Yu Zhengyu , Mao Aihua , Zhou Junming , Lv Lixin , Jiang Jieyuan 
Published: July 2012

ABSTRACT
We report here for the first time the genome sequence of a rearranged porcine circovirus type 2 (PCV2) strain, CH-IVT1, isolated from PCV2-infected PK-15 cells. The complete circular genome of the CH-IVT1 is 605 nucleotides (nt) in length. The finding will help us to understand the molecular evolution of PCV2 and the relationship between PCV2 and PCV-associated diseases.
The provision of paediatric gastrointestinal endoscopy services in the United Kingdom
Authors: Muhammed Rafeeq , Thomson Mike , McGrogan Paraic , Beattie Robert M , Jenkins Huw R 
Published: July 2012

ObjectiveThere are no specific data available regarding paediatric endoscopy provision in the UK and anecdotal experiences suggest that such provision varies widely between the units. The aim of our study was to identify the current provision of paediatric endoscopy services in the UK, the number of endoscopies performed in each unit, the number of operators performing these endoscopies and whether endoscopies were performed under sedation or general anaesthesia.Methods and resultsAn email questionnaire was sent to all 31 units in the UK performing paediatric endoscopies and responses were received from 25 centres (81%). The median number of total endoscopies (upper and lower) per unit each year was 332 (range 64-2040). The median number of gastrosopy per consultant in each centre was 101 (range 20-288) and median number of colonoscopies performed per consultant per year was 49 (range 10-215). 18 of the 25 centres performed all endoscopies under general anaesthesia with 7 centres using sedation as well as general anaesthesia. Percutaneous endoscopic gastrostomy insertion (PEG) was performed in 24 out of 25 centres with the service undertaken by paediatric surgeons in 11 centres. 11 centres provided formal out of hours endoscopy services.ConclusionThere is wide variation in paediatric endoscopy provision and the British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) endoscopy working group is collaborating with the Joint Advisory Group (JAG) to provide specific standards for paediatric endoscopy services in the UK.
Fall and fracture rates following a change from carpet to vinyl floor coverings in a geriatric rehabilitation hospital. A longitudinal, observational study
Authors: Warren Christopher J , Hanger Hugh C 
Published: July 2012

Objective: To investigate whether changing from 5 mm thick carpet tiles to vinyl on a concrete subfloor would alter fall or fracture rates. Design: Longitudinal, observational study. Setting: Six wards (129 beds) of a geriatric rehabilitation hospital. Subjects: All inpatients during this time. Interventions: The floor covering was changed from 5 mm carpet tiles to vinyl on these wards when they were closed for other maintenance. This occurred in stages from November 2007 to December 2009. Measures: Falls are routinely reported using a quality improvement event reporting form. Fall and fracture rates were calculated in the 12 months prior to and following the change in floor covering on each ward. Results: There were 854 falls on the carpet tiles in the 12 months prior to the flooring change and 878 falls on the vinyl in the 12 months after (19.5 and 19.6 falls/1000 bed days, respectively, [ P = 0.95] NS. Fifteen fractures occurred on carpet and 11 fractures on vinyl, [ P = 0.39] NS. Using run charts there were no detectable trends in either the fall or fracture rates following the change in flooring surface. Conclusion: There may be no difference in fall rates or fractures on carpet or vinyl floor covering of similar thickness and subfloor type.
Post-dural (post-lumbar) puncture headache: Risk factors and clinical features
Authors: Amorim Jane A , Gomes de Barros Mauro V , Valença Marcelo M 
Published: July 2012

Objective: This is an analytic, interventional, cross sectional study to evaluate the risk factors of post-dural (post-lumbar) puncture headache (PDPH) and the validity of the diagnostic criteria for PDPH from the ICHD II. Methods: Six-hundred-and-forty patients (332 non-pregnant women and 308 men) aged 8–65 years underwent spinal anesthesia with Quincke 25G or 27G needles in elective surgery. Results: Forty-eight (7.5%) of the patients developed PDPH. The binary logistic regression analysis identified as risk factors: gender [11.1% female vs. 3.6% male, OR 2.25 (1.07–4.73); p  = 0.03], age [11.0% 31–50 years of age vs. 4.2% others, OR 2.21 (1.12–4.36); p  = 0.02], previous history of PDPH [26.4% positive vs. 6.2% negative, OR 4.30 (1.99–9.31); p  < 0.01] and bevel orientation [16.1% perpendicular vs. 5.7% parallel, OR 2.16 (1.07–4.35); p  = 0.03]. The period of latency between lumbar puncture and headache onset range from 6 to 72 hours and the duration from 3 to 15 days. In 34/48 (71%) patients with PDPH, at least one of the following was present: neck stiffness, tinnitus, hypoacusia, photophobia, or nausea. Conclusion: In conclusion, 14/48 patients (29%) suffered none of the above-mentioned symptoms, indicating that a significant number of patients may suffer from PDPH in the absence of any symptoms apart from the headache itself. This suggests that a further analyses of existing studies should be made to determine if a criteria change may need consideration.
Epigeneitc silencing of ribosomal RNA genes by Mybbp1a
Authors: Tan Bertrand Chin-Ming , Yang Chang-Ching , Hsieh Chia-Ling , Chou Yin-Hsiang , Zhong Chang-Zheng , Yung Benjamin Yat-Ming , Liu Hsuan 
Published: July 2012

Abstract

Background
Transcription of the ribosomal RNA gene repeats by Pol I occurs in the nucleolus and is a fundamental step in ribosome biogenesis and protein translation. Due to tight coordination between ribosome biogenesis and cell proliferation, transcription of rRNA and stable maintenance of rDNA clusters are thought to be under intricate control by intercalated mechanisms, particularly at the epigenetic level.

Methods and Results
Here we identify the nucleolar protein Myb-binding protein 1a (Mybbp1a) as a novel negative regulator of rRNA expression. Suppression of rDNA transcription by Mybbp1a was linked to promoter regulation as illustrated by its binding to the chromatin around the hypermethylated, inactive rDNA gene promoters. Our data further showed that downregulation of Mybbp1a abrogated the local DNA methylation levels and histone marks associated with gene silencing, and altered the promoter occupancy of various factors such UBF and HDACs, consequently leading to elevated rRNA expression. Mechanistically, we propose that Mybbp1a maintains rDNA repeats in a silenced state while in association with the negative epigenetic modifiers HDAC1/2.

Conclusions
Results from our present work reveal a previously unrecognized co-repressor role of Mybbp1a in rRNA expression. They are further consistent with the scenario that Mybbp1a is an integral constituent of the rDNA epigenetic regulation that underlies the balanced state of rDNA clusters.
ARAMID–NYLON 6.6 HYBRID CORDS AND INVESTIGATION OF THEIR PROPERTIES
Authors: Yilmaz Berrin 
Published: July 2012

Abstract
Hybrid cords of two different polyamide yarns, poly(p-phenylene terephthalamide; aramid) and poly(hexamethylene adipamide; nylon 6.6) have been investigated. Aramid is a high-tenacity, high-modulus, low-elongation, and thermally stable yarn material. Nylon 6.6 is a high-elongation, low-modulus, high-fatigue-resistant, and good adhering synthetic yarn. The combination of these two different synthetic yarns enables hybrid cords with a diversified range of mechanical properties. The hybrid cord product property diversification is achieved by proper combination of different cord-forming properties of individual plies, such as linear densities, twist levels, ply numbers, treating conditions, and so forth. The effect of linear densities, twist level of plies, and twist level of cabled cord and ply number on the cord properties and also cord performance have been summarized. Aramid yarn having an 1100 linear density has been combined with nylon 6.6 yarn with a different linear density, ranging from 940 to 2100, to form hybrid cord structures. Twisting of aramid and nylon 6.6 yarns has been kept between 150 and 450 twists per meter, while the ply number of aramid and nylon 6.6 yarns has been varied as one and two plies by keeping the total ply number of the cord as three.
Polymorphism‐Dependent Emission for Di(p‐methoxylphenyl)dibenzofulvene and Analogues: Optical Waveguide/Amplified Spontaneous Emission Behaviors
Authors: Gu Xinggui , Yao Jingjing , Zhang Guanxin , Yan Yongli , Zhang Chuang , Peng Qian , Liao Qing , Wu Yishi , Xu Zhenzhen , Zhao Yongsheng , Fu Hongbing , Zhang Deqing 
Published: July 2012

AbstractThe synthesis and optical investigations of di(p‐methoxylphenyl)dibenzofulvene (1) and its analogues 2, 3, 4, 5, 6, and 7 with different lengths of alkoxyl chains are presented. All of these molecules exhibit emission in the solid state. The following interesting properties are reported for compound 1: 1) the solid‐state fluorescence of 1 is dependent on the polymorphism forms; the two crystalline forms 1a and 1b are strongly blue‐ and yellow‐green‐emissive, whereas the amorphous solid is weakly fluorescent with orange emission; 2) on the basis of crystal‐structural analysis, the intermolecular interactions will restrict the internal rotations, leading to fluorescence enhancement for the two crystalline forms 1a and 1b; however, the difference in emission color between 1a and 1b is ascribed to the molecular conformational alteration; 3) the solid‐state fluorescence of 1 can be tuned by heating and cooling as well as grinding. Importantly, microrods of 1a and 1b exhibit outstanding optical waveguide behaviors. Moreover, amplified spontaneous emission for 1b and multimode‐lasing behavior for 1a are presented. Besides the studies of compound 1, the crystal structures and solid‐state fluorescence behaviors of 2, 3, 4, 5, 6, and 7 are also described.
Medium chain acyl‐CoA dehydrogenase deficiency detected among Hispanics by New Jersey newborn screening
Authors: Anderson Sharon , Botti Christina , Li Bo , Millonig James H. , Lyon Elaine , Millson Alison , Karabin Suzanne S.M. , Brooks Susan Sklower 
Published: July 2012

AbstractIn the follow‐up of New Jersey newborn screens suggestive of medium chain acyl‐CoA dehydrogenase deficiency (MCADD) during a 30‐month period, we identified five patients of Hispanic American ethnicity. With information provided by the New Jersey Department of Health and Human Services Newborn Screening program we calculated an overall cumulative incidence of approximately 7.20/100,000 for MCADD; 7.58/100,000 among Hispanic Americans and 7.08/100,000 among non‐Hispanic Americans. Among the five Hispanic American infants who screened positive, a common variant (c.443G>A [p.R148K]) was identified which accounted for 30% of the alleles; c.799G>A (p.G267R) and c.985A>G (p.K329E) each accounted for an additional 20%; and a novel variant c.302G>A (p.G101E) was identified in one patient. Although treated prospectively during interim illnesses to prevent unwanted sequelae; till date, none of the patients carrying the c.443G>A variant have been symptomatic. © 2012 Wiley Periodicals, Inc.
Infants' MTHFR polymorphisms and nonsyndromic orofacial clefts susceptibility: A meta‐analysis based on 17 case–control studies
Authors: Pan Yongchu , Zhang Weibing , Ma Junqing , Du Yifei , Li Dandan , Cai Qi , Jiang Hongbing , Wang Meilin , Zhang Zhengdong , Wang Lin 
Published: July 2012

AbstractMethylenetetrahydrofolate reductase (MTHFR), an important enzyme in folate metabolism, is thought to be involved in the development of nonsyndromic orofacial clefts (NSOC). However, conflicting results have been achieved when evaluating the associations between infants' MTHFR C677T and A1298C polymorphisms and the risk of NSOC. To obtain more precise estimations of these associations, a meta‐analysis recruiting 17 case–control studies was performed. Among Asians we found that CT heterozygote, TT homozygote, and CT/TT of infants' MTHFR C677T variant could contribute to elevated risks of NSOC, compared with CC wild‐type homozygote (OR = 1.741, 95% CI = 1.043–2.907 for CT vs. CC, OR = 2.311, 95% CI = 1.313–4.041 for TT vs. CC, and OR = 1.740, 95% CI = 1.051–2.882 for CT/TT vs. CC, respectively). Similar effect was also observed on MTHFR 677T T allele, when using C allele as a reference in Asians (OR = 1.420, 95% CI = 1.191–1.693, for T allele vs. C allele). Furthermore, in stratified analysis by types of disease, CT/CC was suggested to confer decreased susceptibility to CL/P under recessive genetic model (OR = 0.854, 95% CI = 0.730–1.000). For MTHFR A1298C, the MTHFR 1298C allele in the case group of Caucasians was significantly lower than that in the control group, suggesting a protective effect against NSOC in Caucasian populations (OR = 0.711, 95% CI = 0.641–0.790, for C allele vs. A allele). In conclusion, the meta‐analysis provided confirmative evidences that infants' MTHFR C677T and A1298C polymorphisms were involved in the development of NSOC. © 2012 Wiley Periodicals, Inc.
Electron Transfer Reactions Between Iron (III) and Substituted Ferrocenes in Cationic and Non‐Ionic Micellar Systems
Authors: Carbone Antonio I. , Paolo Cavasino F. , Sbriziolo Carmelo , Pelizzetti Ezio 
Published: July 2012

AbstractThe kinetics of the electron transfer reactions of aquoiron(III) with ferrocene (Fer) and its n‐butyl (BFer), 1,1′‐dimethyl (DMFer) and 1,1′‐di‐n‐butyl (DBFer) derivatives have been studied in the presence of cationic (CTAN) and non‐ionic (Triton X‐100) micelles at 20.0°C and ionic strength 0.02 mol dm−3. Both surfactants inhibit nearly at the same extent the reaction involving a given ferrocene derivative. The rate inhibition depends strongly on the alkyl groups present in the molecule of ferrocene, following the order DBFer > BFer > DMFer > Fer. The binding constants and the contribution of a methylene (or methyl) group of the alkyl substituents to the transfer free energy from water to micelle have been estimated and discussed, suggesting that ferrocenes are located inside the micelle.
Solubility of Hydrogen in Titanium Alloys. I. The Solubility of Hydrogen in the System Ti1‐xGax, 0 ≦ x ≦ 0.25
Authors: Mrowietz Michael , Weiss Alarich 
Published: July 2012

AbstractApplying the manometric method, the solubility of hydrogen in alloys Ti1‐xGax was studied in the range 0 ≦ x ≦ 25; 5 · 10−5 ≦ pH2/bar ≦ 1; 773 ≦ T/K ≦ 1298. Within the given range of p and T the phase diagram of Ti1‐xGaxHr was investigated for 9 compositions x. In the range of solid solutions, 0 ≦ x ≦ 0.11, with increasing x the range Δr of the hcp phase α‐Ti1‐xGaxHr increases slightly, whereas the range of the bcc phase β‐Ti1‐xGaxHr, narrows strongly with increasing x. The width Δr of the two phase region α + β is nearly independent of x and the phase boundary between β‐phase and (β + γ) region shifts with decreasing Δr of the β‐phase to smaller r. In α‐T1‐xGaxHr the enthalpy of hydrogen solution ΔHH is practically independent of r but depends slightly on x, decreasing from ‐46.0 kJ mol−1 (x = 0) to ‐46.5 kJ mol−1 (x = 0.10). In the bcc phase β‐Ti1‐xGaxHr, ΔHH decreases markedly from ‐57 kJ mol−1 (r → 0) to ‐70 kJ mol−1 (r ⇌ 1). ΔHH is independent of the gallium content x within the limits of error. — Assuming a plausible blocking model for the occupancy of interstitial sites in the metal matrix by hydrogen, the excess entropies of dissolved hydrogen were evaluated. In α‐Ti1‐xGaxHr an increase of ΔSEH is found with increasing r from ‐55 JK−1 mol−1 (r→0) to ‐53 JK−1 mol−1 (r = 0.1). ΔSEH depends much stronger on r in β‐Ti1‐xGaxHr: ΔSEH = ‐70 JK−1 mol−1 (r→0); ΔSEH = ‐66.5 JK−1 mol−1 (r = 0.8). There is negligible influence of x on ΔSEH in both phases. — In the ordered hcp phase α2‐Ti3GaHr there is an increase of exothermicity compared to α‐Ti1‐xGaxHr. ΔHH (r → 0) is ‐51.3 kJ mol−1 for the ordered phase and it depends on r, increasing to ‐50 kJ mol−1 at r ⇌ 0.1. ΔSEH for this phase is independent of r, ΔSEH = ‐53 JK−1 mol−1. — Additional data on the hydrogen solubility in α‐Ti3Sb are given, resulting on more accurate thermodynamic data ΔHH, ΔSH, and ΔSEH.
Dynamics of Trans‐Cis Photoisomerization of Stilbene in Hydrocarbon Solutions
Authors: Sundström Villy , Gillbro Tomas 
Published: July 2012

AbstractWe have determined the intramolecular potential barrier as well as total activation energies of trans‐cis isomerization in the excited state of stilbene in hydrocarbons, using UV picosecond transient‐absorption Spectroscopy. The dynamics of the isomerization is compared with theoretical predictions offered by the activated barrier crossing models of Kramers, and Grote and Hynes.
Tunable VUV Laser Excitation of H2
Authors: Meier W. , Rottke H. , Zacharias H. , Welge K. H. 
Published: July 2012

AbstractRotational state selective single photon excitation of H2 in the (0 — 0) and (3 — 0) bands of the B 1Σ+u ← X1Σ+g transition around λ = 111.0 nm and λ = 106.3 nm has been performed in a molecular beam. VUV laser induced fluorescene detection will be compared with resonantly enhanced two photon ionization where a second UV laser for ionization of the excited B state was employed.