bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is There a Place for Pseudostuttering Assignments in Speech-Language Pathology Training Within the Neurodiverse Paradigm?
Authors: Bortz Mellissa A. 
Published: April 2024

Purpose:
The continued use of pseudostuttering assignments, a disability simulation for speech-language pathology students, needs to be reexamined to align with neurodiversity and students' reluctance to participate in these studies. Stuttering, from a neurodiverse perspective, is regarded as a normal speech variation, rather than a disorder. The purpose of this research was for people who stutter, speech-language therapy students, and faculty members to respond to a survey to determine the future of these assignments, in terms of developing empathy and clinical skills of pseudostuttering.

Method:
A descriptive design electronic survey using typical case sampling was disseminated globally. A total of 134 participants, divided into three participant groups, completed the survey. The survey consisted of 84 closed- and open-ended questions. Percentages and thematic analysis were used to determine the results.

Results:
Quantitative and qualitative analyses indicated that 83% of speech-language pathology faculty members supported these assignments. Forty-eight percent of people who stutter and 58% of speech-language pathology students felt negatively toward pseudostuttering assignments. Students reported being more comfortable performing augmentative and alternative communication simulations than pseudostuttering or aphasia simulations. Students were concerned that pseudostuttering assignments were offensive and stigmatizing for people who stutter.

Conclusions:
The results reflect the benefits of partnering with all the constituent groups. Adaptations to pseudostuttering assignments, such as speaking with people who stutter and adopting a neurodiverse, inclusive approach to student education, are recommended.
Gas, not dust: Migration of TESS/Gaia hot Jupiters possibly halted by the magnetospheres of protoplanetary disks
Authors: Mendigutía I. , Lillo-Box J. , Vioque M. , Maldonado J. , Montesinos B. , Huélamo N. , Wang J. 
Published: April 2024

Context. The presence of short-period (< 10 days) planets around main sequence (MS) stars has been associated either with the dust-destruction region or with the magnetospheric gas-truncation radius in the protoplanetary disks that surround them during the pre-MS phase. However, previous analyses have only considered low-mass FGK stars, making it difficult to disentangle the two scenarios.
Aims. This exploratory study is aimed at testing whether it is the inner dust or gas disk driving the location of short-period, giant planets.
Methods. By combining TESS and Gaia DR3 data, we identified a sample of 47 intermediate-mass (1.5−3 M⊙) MS stars hosting confirmed and firm candidate hot Jupiters. We compared their orbits with the rough position of the inner dust and gas disks, which are well separated around their Herbig stars precursors. We also made a comparison with the orbits of confirmed hot Jupiters around a similarly extracted TESS/Gaia sample of low-mass sources (0.5−1.5 M⊙).
Results. The orbits of hot Jupiters around intermediate-mass stars tend to be closer to the central sources than the inner dust disk, most generally consistent with the small magnetospheric truncation radii typical of Herbig stars (≲5 R*). A similar study considering the low-mass stars alone has been less conclusive due to the similar spatial scales of their inner dust and gas disks (≳5 R*). However, considering the whole sample, we do not find the correlation between orbit sizes and stellar luminosities that is otherwise expected if the dust-destruction radius limits the hot Jupiters’ orbits. On the contrary, the comparative analysis reveals that such orbits tend to be closer to the stellar surface for intermediate-mass stars than for low-mass stars, with both being mostly consistent with the rough sizes of the corresponding magnetospheres.
Conclusion. Our results suggest that the inner gas (ad not the dust) disk limits the innermost orbits of hot Jupiters around intermediate-mass stars. These findings also provide tentative support to previous works that have claimed this is indeed the case for low-mass sources. We propose that hot Jupiters could be explained via a combination of the core-accretion paradigm and migration up to the gas-truncation radius, which may be responsible for halting inward migration regardless of the stellar mass regime. Larger samples of intermediate-mass stars with hot Jupiters are necessary to confirm our hypothesis, which implies that massive Herbig stars without magnetospheres (> 3−4 M⊙) may be the most efficient in swallowing their newborn planets.
Comparing the dynamics of Jupiter-family Comets and comet-like fireballs
Authors: Shober P. M. , Tancredi G. , Vaubaillon J. , Devillepoix H. A. R. , Deam S. , Anghel S. , Sansom E. K. , Colas F. , Martino S. 
Published: April 2024

Context. Jupiter-family comets (JFCs), which originate from the Kuiper belt and scattered disk, exhibit low-inclination and chaotic trajectories due to close encounters with Jupiter. Despite their typically short incursions into the inner solar system, a notable number of them are on Earth-crossing orbits, with fireball networks detecting many objects on “JFC-like” (2 < TJ < 3) orbits.
Aims. This investigation aims to examine the orbital dynamics of JFCs and comet-like fireballs over 104 yr timescales, focusing on the trajectories and stability of these objects in the context of gravitational interactions within the solar system.
Methods. We employed an extensive fireball dataset from Desert Fireball Network (DFN), European Fireball Network (EFN), Fireball Recovery and InterPlanetary Observation Network (FRIPON), and Meteorite Observation and Recovery Project (MORP), alongside telescopically observed cometary ephemeris from the NASA HORIZONS database. The study integrates 646 fireball orbits with 661 JFC orbits for a comparative analysis of their orbital stability and evolution.
Results. The analysis confirms frequent Jupiter encounters among most JFCs, inducing chaotic orbital behavior with limited predictability and short Lyapunov lifetimes (~120 yr), underscoring Jupiter’s significant dynamical influence. In contrast, “JFC-like” meteoroids detected by fireball networks largely exhibit dynamics divergent from genuine JFCs, with 79–92% on “JFC-like” orbits shown not to be prone to frequent Jupiter encounters; in particular, only 1–5% of all fireballs detected by the four networks exhibit dynamics similar to that of actual JFCs. In addition, 22% (16 of 72) of near-Earth JFCs are on highly stable orbits, suggesting a potential main belt origin for some of the bodies.
Conclusions. This extensive study delineates the stark dynamical contrast between JFCs and JFC-like meteoroids detected by global fireball networks. The majority of centimeter- and meter-scale meteoroids on JFC-like orbits exhibit remarkably stable trajectories, which starkly differ from the chaotic paths of their km-scale counterparts. Our findings suggest that the JFC-like objects observed by fireball networks predominantly originate from the outer main belt, with only a minor fraction being directly attributable to traditional JFCs.
The power of binary pulsars in testing Gauss-Bonnet gravity
Authors: Yordanov Petar Y. , Staykov Kalin V. , Yazadjiev Stoytcho S. , Doneva Daniela D. 
Published: April 2024

Context. Binary pulsars are a powerful tool for probing strong gravity that still outperform direct gravitational wave observations in a number of ways due to the remarkable accuracy of the pulsar timing. They can constrain the presence of additional charges of the orbiting neutron stars very precisely, leading to new channels of energy and angular momentum loss, such as scalar dipole radiation.
Aims. In the present paper, we explore in detail the possibility of constraining different classes of scalar-Gauss-Bonnet gravity with binary pulsars. Additionally, we updated the existing constraints related to the observed maximum mass of neutron stars.
Methods. Interestingly, depending on the equation of state, the resulting limits on the theory coupling parameters can outperform the constraints coming from binary merger observations by up to a factor of two, even for so-called Einstein-dilaton-Gauss-Bonnet gravity where neutron stars are often underestimated as relevant theory probes. As an additional merit, precise Bayesian methods are compared with approximate approaches, with the latter showing a very good performance despite their simplicity.
Evolution of the magnetic field rotation distributions in the inner heliosphere
Authors: Larosa A. , Chen C. H. K. , McIntyre J. R. , Jagarlamudi V. K. , Sorriso-Valvo L. 
Published: April 2024

Context. The nature and evolution of the solar wind magnetic field rotations is studied in data from the Parker Solar Probe.
Aims. We investigated the magnetic field deflections in the inner heliosphere below 0.5 au in a distance- and scale-dependent manner to shed some light on the mechanism behind their evolution.
Methods. We used the magnetic field data from the FIELDS instrument suite to study the evolution of the magnetic field vector increment and rotation distributions that contain switchbacks.
Results. We find that the rotation distributions evolve in a scale-dependent fashion. They have the same shape at small scales regardless of the radial distance, in contrast to larger scales, where the shape evolves with distance. The increments are shown to evolve towards a log-normal shape with increasing radial distance, even though the log-normal fit works quite well at all distances, especially at small scales. The rotation distributions are shown to evolve towards a previously developed rotation model moving away from the Sun.
Conclusions. Our results suggest a scenario in which the evolution of the rotation distributions is primarily the result of the expansion-driven growth of the fluctuations, which are reshaped into a log-normal distribution by the solar wind turbulence.
Recurrent Venous Thromboembolism in Patients on Anticoagulation: An Update Based on the Revised AWMF S2k Guideline
Authors: Klamroth Robert , Riess Hanno , Beyer-Westendorf Jan , Linnemann Birgit 
Published: April 2024

AbstractIn the recently updated German S2k Guideline “Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism,” a new chapter was incorporated about recurrent venous thromboembolism (VTE) in patients on anticoagulation treatment. Despite the high efficacy of anticoagulation in most patients, approximately 2% experience a recurrent VTE event while receiving anticoagulant drugs. The proper diagnosis of the recurrent VTE is important and possible only with the knowledge of localization and thrombus burden of the primary VTE event. Possible reasons for recurrent VTE events in patients on anticoagulation are non-adherence to medication, sub-therapeutic drug levels due to resorption disorders or drug interactions, or concomitant disease with high thrombogenicity. Cancer is the most common underlying disease, but it is important to investigate and understand possible other causes whenever a breakthrough VTE event occurs. This results in the recommendation that in patients with VTE recurrence on therapeutic anticoagulation, in particular, the presence of malignant disease, antiphospholipid syndrome, and rare diseases like paroxysmal nocturnal hemoglobinuria or Behçet's disease should be considered. For VTE recurrence during heparin therapy, heparin-induced thrombocytopenia type II needs to be ruled out, even if platelet counts are within the normal range. Although the mechanisms of recurrence on anticoagulation can be evaluated in a certain degree, clinical evidence for the management of recurrent VTE in anticoagulated patients is minimal and mainly based on expert opinion. Switching anticoagulant medication and intensifying anticoagulant treatment are possible options.
Pulmonary Embolism: An Update Based on the Revised AWMF-S2k Guideline
Authors: Opitz Christian F. , Meyer F. Joachim 
Published: April 2024

AbstractPulmonary embolism (PE) is the third most common acute cardiovascular disease. The risk of PE increases with age and mortality is high. Patients are stratified into hemodynamically stable versus unstable patients, as this has important implications for diagnosis and therapy. Since clinical signs and symptoms of acute PE are nonspecific, the clinical likelihood of PE is estimated to guide diagnostic pathways. D-dimer testing is performed in hemodynamically stable patients with low or intermediate probability of PE and the visualization of thromboembolism and its sequelae is commonly achieved with computed tomography pulmonary angiography (CTPA), supplemented by ultrasound techniques. With confirmed PE, another risk stratification estimates disease severity and defines intensity and setting of the ensuing treatment. The therapeutic spectrum ranges from outpatient treatment with initial oral anticoagulation to thrombolytic or interventional treatment in the intensive care unit or catheterization laboratory. In single cases, even acute surgical thrombectomy is attempted.
Low-/Negative-Pressure Hydrocephalus: To Understand the Formation Mechanism from the Perspective of Clinicians
Authors: Li Guangzhao , Lin Bin , Yang Fei 
Published: April 2024

AbstractLow-/negative-pressure hydrocephalus (LPH/NePH) is uncommon in clinical practice, and doctors are unfamiliar with it. LPH/NePH is frequently caused by other central nervous system diseases, and patients are frequently misdiagnosed with other types of hydrocephalus, resulting in delayed treatment. LPH/NePH therapy evolved to therapeutic measures based on “external ventricular drainage below atmospheric pressure” as the number of patients with LPH/NePH described in the literature has increased. However, the mechanism of LPH/NePH formation is unknown. Thus, understanding the process of LPH/NePH development is the most important step in improving diagnosis and treatment capability. Based on case reports of LPH/NePH, we reviewed theories of transcortical pressure difference, excessive cerebral venous drainage, brain viscoelastic changes, and porous elastic sponges.
Predictors of Prolonged Mechanical Ventilation in Pediatric Patients with Hemolytic Uremic Syndrome
Authors: Bhakta Rupal T. , Brown Clare C. , Garcia Xiomara , Dachepally Rashmitha , Prodhan Parthak 
Published: April 2024

AbstractThis study aimed to analyze factors associated with mechanical ventilation (MV) and prolonged MV (≥12 days) in pediatric hemolytic uremic syndrome (HUS) patients. Retrospective multicenter cohort study analyzed data from 3,831 pediatric HUS (age <18 years) patients between 2004 and 2018 from Pediatric Health Information System database. Multivariate logistic regression was used to pinpoint factors associated with MV and prolonged MV. Among 3,831 patients analyzed, 769 (20%) patients required MV, 166 (23.6%) of them were prolonged MV. Factors independently associated with prolonged MV include African American (adjusted odds ratio [aOR]: 1.98, 95% confidence interval [CI]: 1.11–3.54, p = 0.02), children aged between 1 and 5 years (aOR: 7.69, 95% CI: 3.71–15.93, p < 0.001), pneumonia (aOR: 2.54, 95% CI: 1.51–4.25, p < 0.001), pneumothorax (aOR: 2.41, 95% CI: 1.08–5.39, p = 0.032), liver dysfunction (aOR: 3.22, 95% CI: 1.68–6.16, p < 0.001), ileus with perforation (aOR: 1.83, 95% CI: 1.03–3.25, p = 0.039), and sepsis (aOR: 1.97, 95% CI: 1.26–3.08, p = 0.003). In pediatric HUS cases, 20% required MV, and 23.6% of them were prolonged MV. Factors associated with prolong MV include African American race, children aged between 1 and 5 years, pneumonia, pneumothorax, liver dysfunction, ileus with perforation, and sepsis.
The Diagnostic Yield of Chromosomal Microarray Analysis in Third-Trimester Fetal Abnormalities
Authors: Elron Eyal , Maya Idit , Shefer-Averbuch Noa , Kahana Sarit , Matar Reut , Klein Kochav , Agmon-Fishman Ifat , Gurevitch Merav , Basel-Salmon Lina , Levy Michal 
Published: April 2024

Objective This study aimed to determine the diagnostic yield of chromosomal microarray analysis (CMA) performed in cases of fetal abnormalities detected during the third trimester of pregnancy.
Study Design A retrospective review of medical records was conducted for women who underwent amniocentesis at or beyond 28 weeks of gestation between January 2017 and February 2023. CMA results of pregnancies with abnormal sonographic findings not detected before 28 weeks were included.
Results A total of 482 fetuses met the inclusion criteria. The average maternal age was 31.3 years, and the average gestational age at amniocentesis was 32.3 weeks. The overall diagnostic yield of CMA was 6.2% (30 clinically significant copy number variations [CNVs]). The yield was 16.4% in cases with two or more fetal malformations, while cases with a single anomaly revealed a diagnostic yield of 7.3%. Cases presenting isolated polyhydramnios or isolated fetal growth restriction had a lower yield of 9.3 and 5.4%, respectively. Of the 30 clinically significant cases, 19 (or 63.4%) exhibited recurrent CNVs. The remaining 11 cases (or 36.6%) presented unique CNVs. The theoretical yield of Noninvasive Prenatal Testing (NIPT) in our cohort is 2% for aneuploidy, which implies that it could potentially miss up to 70% of the significant findings that could be identified by CMA. In 80% of the fetuses (or 24 out of 30) with clinically significant CNVs, the structural abnormalities detected on fetal ultrasound examinations corresponded with the CMA results.
Conclusion The 6.2% detection rate of significant CNVs in late-onset fetal anomalies confirms the value of CMA in third-trimester amniocentesis. The findings underscore the necessity of CMA for detecting CNVs potentially overlooked by NIPT and emphasize the importance of thorough genetic counseling.
Key Points
Reversal of drug resistance in breast cancer cells by photodynamic action mediated by curcumin/Ko143/PLGA nanoparticles
Authors: Wang Junchao , Han Xiaoyu , Bai Dingqun 
Published: April 2024

Objective: The objective of this study is to prepare Cur/Ko143/PLGA that encapsulate the photosensitizer curcumin (Cur) and the multidrug transporter-specific inhibitor Ko143 to investigate its application in reversing drug resistance in breast cancer and evaluate its properties and therapeutic efficacy. Results: After successful preparation of nanoparticles, the encapsulation rate of Cur/Ko143/PLGA was 73.8% ± 1.8%, and the drug loading rate was 2.8% ± 0.1%. The Cur/Ko143/PLGA were spherical and regular in morphology under transmission electron microscopy. The nanoparticles were morphologically intact, were uniform in size, and did not show significant aggregation under scanning electron microscopy. The average particle size of Cur/Ko143/PLGA was 232.32 ± 10.60 nm, the polymer dispersion index was 0.01, and the zeta potential was −17.25 ± 0.65 mV, as determined by laser particle sizing. In vitro ultrasound observation showed that Cur/Ko143/PLGA were enhanced in both the B-mode and contrast modes. Intracellular Cur fluorescence detection, biocompatibility testing, cell scratch experiment, flow detection of apoptosis, live–dead staining, and actin polymerization test all prove that new nanomaterials have better photodynamic efficacy. Conclusion: Drug-carrying Cur/Ko143/PLGA nanoparticles can increase the concentration of the intracellular photosensitizer Cur and increase the photodynamic efficacy by inhibiting an efflux pump, which is expected to become a new therapeutic strategy.
Why not focus on combating the virus?
Authors: Zuo Baiyao 
Published: April 2024

Abstract
“Egocentrism” in communication usually refers to the fact that interlocutors are subconsciously influenced by
their cognitive environment. However, being egocentric may be the product of the interlocutors’ conscious choice rather than the
unavoidable impact of cognitive experience. In order to explore some emotive conflicts during the fight against COVID-19 in China,
this study distinguishes active egocentrism from passive egocentrism. We further contend that the interplay of the cognitive
environment and the active assessment of social context differ in speaker processing and hearer processing, which may result in
emotive miscommunications. The facets of the actual social context assessed by interlocutors are also investigated to explain the
formation of active egocentrism.
Argon admixture-driven enhanced ionization and performance of a 5 kW Hall thruster on krypton
Authors: Lee Dongho , Brabston William P , Lev Dan , Walker Mitchell L R 
Published: April 2024

Abstract
Utilizing alternative propellants has been recognized as a strategy to reduce the total cost of propellants in electric propulsion-based missions. The aim of this study is to quantify the Hall effect thruster (HET) performance and operating characteristics using a Kr–Ar mixture to enable mission designers to evaluate the impact on mission and spacecraft design. We present the performance and plume plasma properties of the P5 5 kW-class HET operated with a Kr–Ar mixture with Ar volumetric flow rate fractions from 0 to 100%. The thruster is characterized at discharge power levels of 2.6 kW and 4.1 kW at constant discharge current and voltage over the range of Ar fractions. Despite higher ionization energy and lower mass of Ar, the thruster exhibited a similar level of thrust within 2% when comparing the pure Kr and 26%-Ar mixture cases. The derived ion energy distribution functions and analytical modeling suggest that the characteristic length for the ionization region is extended as the Ar fraction increases. The increased residence time of Kr at the extended ionization region and background energetic electrons from the ionized Ar neutrals are considered to cause this enhanced ionization of the injected Kr neutrals. This leads to a 6% higher Kr ion density at the 26%-Ar case even at the 16% less injected Kr neutral density than in the pure Kr case. The enhanced Kr ionization and generated Ar ions in the 26%-Ar case consequently led to a comparable thrust with that of the pure Kr case. The study indicates that mixing Ar with approximately 26% volumetrically with Kr can provide a similar or even higher thrust performance at the same discharge power. This will be particularly advantageous for various space missions that require high impulses by reducing the total cost of the propellant.
Improving the output performance of magnetic energy harvesters through coupling beam
Authors: You Zhixiong , Shi Yang , Miao Huining 
Published: April 2024

Abstract
We propose a novel magnetic energy harvester (MEH) with multiple resonance modes. The MEH consists of low-frequency and high-frequency piezoelectric cantilevers connected by a coupling beam. Theoretical modeling, simulation, and experiments were conducted to validate the multiple resonance phenomenon. The results from these investigations are consistent with each other. It is evident that the internal coupling (IC) effect resulting from the coupling beam facilitates significant voltage outputs from both cantilevers at their respective resonant frequencies, i.e. the low-frequency beam (LFB) resonates at the resonant frequency of the high-frequency beam (HFB), resulting in a remarkable 122% increase in the output voltage. Conversely, the HFB resonates at the resonant frequency of the LFB, leading to an astounding 1200% increase in the output voltage. As a result of the IC phenomenon, the operating frequency bandwidth for harvesting an output voltage of more than 1 V in the LFB has been extended by 35.3%, while that of the HFB for capturing an output voltage of more than 0.5 V has been extended by 62.5%. Additionally, the coupling effect significantly enhances the power output of the MEH.