bluuebunny/crossref_metadata_2025_split huggingface dataset:
The efficacy of Punica granatum extract gel in the treatment of symptomatic oral lichen planus in an Indian population: A clinical study
Authors: Mahapatra Subharina , Hebbale Manjula , Mhapuskar Amit , Halli Rajshekhar , Jadhav Santosh 
Published: April 2024

Abstract

INTRODUCTION:
The autoimmune disorder, oral lichen planus (OLP), primarily affects oral mucous membranes. Current drug treatments are only palliative and have serious side effects. Pomegranate has been used as a potential herbal remedy for the treatment of OLP.

MATERIALS AND METHODS:
The study consisted of a sample size of 30 individuals who were diagnosed with symptomatic OLP based on both clinical and histological evidence and were equally assigned to Group A (4% topical Punica granatum seed extract gel, which has been customized for this particular study purpose only) and Group B (0.1% topical steroid). All patients were evaluated for the outcome criteria of pain, burning sensation, and lesion size.

RESULTS:
In the present study, results were highly statistically significant (P = 0.001) in intragroup observation for both Group A and Group B from baseline to the end of 30 days of follow-up for all three parameters. There was no statistically significant difference between groups for each week of follow-up.

CONCLUSION:

P. granatum has been used in very few studies, but this is one of the few where a gel made from P. granatum seed extract is used as an oral gel. In conclusion, it can be said that topical P. granatum extract gel is as good as topical corticosteroids at getting rid of the signs and symptoms of OLP, so it can be used as an alternative treatment.
Monkeypox: A re-emerging disease
Authors: Kaur Narinderpal , Dabar Jatin , Bassi Pallavi 
Published: April 2024

Abstract
The virus known as monkeypox is the source of the zoonotic disease monkeypox, which was historically widespread in Central Africa and West Africa. The cases of monkeypox in humans are uncommon outside of West and Central Africa, but copious nonendemic nations outside of Africa have recently confirmed cases. People when interact with diseased animals, then, they may inadvertently contact monkeypox. There are two drugs in the market: brincidofovir and tecovirimat and both of these drugs are permitted for the cure of monkeypox by the US Food and Drug Administration. The present review summarizes the various parameters of monkeypox in context with transmission, signs and symptoms, histopathological and etiological changes, and possible treatment. Monkeypox is clinically similar to that of smallpox infection but epidemiologically, these two are different, the present study also signifies the main differences and similarities of monkeypox to that of other infectious diseases. As it is an emerging disease, it is important to know about the various factors related to monkeypox so as to control it on a very early stage of transmission.
Sparse-view cone-beam computed tomography iterative reconstruction based on new multi-gradient direction total variation
Authors: Cui Junlong , Hou Yong , Jiang Zekun , Yu Gang , Ye Lan , Cao Qiang , Sun Qian 
Published: April 2024

ABSTRACTAim:The accurate reconstruction of cone-beam computed tomography (CBCT) from sparse projections is one of the most important areas for study. The compressed sensing theory has been widely employed in the sparse reconstruction of CBCT. However, the total variation (TV) approach solely uses information from the i-coordinate, j-coordinate, and k-coordinate gradients to reconstruct the CBCT image.Materials and Methods:It is well recognized that the CBCT image can be reconstructed more accurately with more gradient information from different directions. Thus, this study introduces a novel approach, named the new multi-gradient direction total variation minimization method. The method uses gradient information from the ij-coordinate, ik-coordinate, and jk-coordinate directions to reconstruct CBCT images, which incorporates nine different types of gradient information from nine directions.Results:This study assessed the efficacy of the proposed methodology using under-sampled projections from four different experiments, including two digital phantoms, one patient’s head dataset, and one physical phantom dataset. The results indicated that the proposed method achieved the lowest RMSE index and the highest SSIM index. Meanwhile, we compared the voxel intensity curves of the reconstructed images to assess the edge structure preservation. Among the various methods compared, the curves generated by the proposed method exhibited the highest level of consistency with the gold standard image curves.Conclusion:In summary, the proposed method showed significant potential in enhancing the quality and accuracy of CBCT image reconstruction.
Gastrointestinal bleeding due to obstruction of the superior mesenteric vein
Authors: Liu Feng , Li Aiyin , Li Guijie , Liu Hairong 
Published: April 2024

ABSTRACT
Gastrointestinal bleeding is a common clinical symptom. Finding the underlying cause is the first step for treatment. In a few patients, this can be difficult. The present work reports on the unusual case of a 53-year-old man who presented gastrointestinal bleeding. No bleeding site was found by gastrocolonoscopy or interventional examination, but after multidisciplinary consultation, we discovered that the cause of gastrointestinal bleeding was the obstruction of the upper mesenteric vein.
Rational use of prescribing power of a physician
Authors: Rath Sudhanshu Kumar 
Published: April 2024

Abstract
Writing a prescription is a duty, responsibility and a power has to be used diligently. For various reasons, our prescription sometimes becomes longer than necessary. Multiple medications can be associated with adverse outcome. Co-prescription of proton pump inhibitors with analgesics and probiotics with antibiotics may not be required routinely. Human chorionic gonadotrophin for threatened abortion deserves a relook. Progesterone during pregnancy has been overstretched. Vitamins supplementation has its place only in specific situations but tends to be over-prescribed. A rational approach while prescribing would be scientific as well as pocket-friendly to the patient.
The effect of oxygen-inhibited layer and its inhibition technique on diametral tensile strength values of various nanofilled composite resin types
Authors: Hadi Steward , Tjandrawinata Rosalina , Fibryanto Eko 
Published: April 2024

Abstract

Aim:
To investigate the impact of different inhibitory techniques on the thickness of oxygen-inhibited layer (OIL) and diametral tensile strength (DTS) value in various types of nanofilled composite resins.

Materials and Methods:
Thirty-six nanofilled composite resins specimens, consisting of packable, flowable, high-viscosity bulk-fill (HVBF), low-viscosity bulk-fill (LVBF), shaped as half disk (diameter: 6 mm and height 3 mm) and randomly allocated to three groups (n = 3): with Mylar strip, glycerin application, and without OIL inhibitors. OIL thickness was observed with an optical microscope. Furthermore, 60 specimens of composite resins were incrementally created in disk-shaped molds (diameter: 6 mm, height: 1.5 mm × 2 mm). DTS measurements were carried out using a universal testing machine. Data were statistically analyzed using a two-way analysis of variance (ANOVA) test and Pearson’s correlation test (P < 0.05).

Results:
OIL inhibitor techniques (Mylar strip and glycerin) significantly affected OIL formation across various types of nanofilled composite resins (P < 0.05). Changes were also observed in how these techniques influenced DTS values. Correlation analysis indicated a positive relationship between OIL thickness and DTS value.

Conclusions:
Application of Mylar strip and glycerin reduced OIL thickness and DTS values in packable, flowable, HVBF, LVBF nanofilled composite resins. Glycerin proved to be more effective than Mylar strips in reducing OIL thickness, which is reflected in the DTS values of nanofilled composite resins. Greater OIL layer thickness on the outermost layer of the nanofilled composite resin correlated with a higher DTS value.
Aerosol drug therapy in critically ill patients (Aero-in-ICU study): A multicentre prospective observational cohort study
Authors: Singhal Sanjay , Gurjar Mohan , Sahoo Jyoti Narayan , Saran Sai , Dua Ruchi , Sahoo Alok Kumar , Sharma Ankur , Agarwal Sonika , Sharma Arun , Ghosh Pralay Shankar , Rao Parnandi Bhaskar , Kothari Nikhil , Joshi Krupal , Deokar Kunal , Mukherjee Sudipta , Sharma Prakhar , Sreedevi Billa PS , Sivaramakrishnan Prakash , Singh Umadri , Sundaram Dhivya , Agrawal Avinash , Katoch Chandan Dev Singh 
Published: April 2024

Background:
In recent years, a significant understanding of delivering optimal aerosol therapy and the availability of various drugs and devices have led to an increase in its use in clinical practice. There are only a few studies available regarding their use in critically ill patients from a few parts of the world. We aimed to study the practice pattern of aerosol therapy in critically ill patients from Indian intensive care units (ICUs).

Methods:
After ethical approval, this multi-centric prospective observational study was performed over a study period of four weeks. Newly admitted adult patients considered who had an artificial airway and/or ventilation (including non-invasive). Patients were followed up for the next 14 days or until ICU discharge/death (whichever came first) for details of each aerosol therapy, including ongoing respiratory support, drug type, and aerosol-generating device.

Results:
From the nine participating centers across India, 218 patients were enrolled. Of 218 enrolled patients, 72.48% received 4884 aerosols with 30.91 ± 27.15 (95%CI: 26.6-35.1) aerosols per patient over 1108 patient days. Approximately 62.7% during IMV, 30.2% during NIV, 2.3% in spontaneously breathing patients with an artificial airway during weaning, and 4.7% were given without an artificial airway after weaning or decannulation. In 59%, a single drug was used, and bronchodilators were the most frequent. The jet nebulizer was the most common, followed by the ultrasonic and vibrating mesh aerosol generator. The ventilator setting was changed in only 6.6% of the aerosol sessions with IMV and none with NIV.

Conclusion:
Aerosol therapy is frequently used with a wide variation in practices; bronchodilators are the most commonly used drugs, and jet nebulizers are the most widely used.
Management of primary childhood glaucoma: Evaluation of practice, practice gaps, and needs in a low-resource country
Authors: Ugalahi Mary , Sarimiye Tarela Frederick , Obajolowo Tokunbo , Nkanga Elizabeth Dennis , Abdulrahman Amina , Olusanya Bolutife , Baiyeroju Aderonke 
Published: April 2024

Abstract

Purpose:
To evaluate the current practice, equipment availability, and training needs for managing childhood glaucoma in Nigeria.

Materials and Methods:
An online questionnaire (Google Forms) was distributed through E-mails and social media platforms of pediatric ophthalmologists and glaucoma specialists who practice in Nigeria and manage glaucoma in children aged 0–16 years. Information concerning sociodemographic characteristics, type of practice, location of practice, years of practice, status, and preferred practices in the management of childhood glaucoma cataracts were obtained and analyzed with SPSS.

Results:
Thirty (23.3%) out of 129 eligible participants indicated they perform glaucoma surgeries in children. The majority (66.6%) had practiced as specialists for 10 years or less, and 70% were pediatric ophthalmologists. A third of the respondents practiced in the country’s southwest region, with none in the Northeast region. The most common surgery performed for primary congenital glaucoma was combined trabeculotomy trabeculectomy, while trabeculectomy was the most common surgery performed for juvenile open-angle glaucoma. Two respondents reported performing glaucoma drainage device surgery and seven reported possessions of skills for goniotomy. All centers had trabeculectomy instrument sets, while three centers had facilities for endolaser cyclophotocoagulation, and only two centers had knives for goniotomy. Antimetabolites were routinely used for childhood glaucoma surgeries by 26 (86.7%) respondents, and the most common antimetabolite used was mitomycin (21; 80.8%).

Conclusion:
There is a need for the development of in-country training programs and the exchange of skills through collaboration among those providing glaucoma services within Nigeria to improve the care of children with glaucoma.
Outcomes of Adjunctive Therapy with Open Arthrotomy for Patients with Septic Arthritis Due to Melioidosis: A Retrospective Study
Authors: Chittrakarn Sorawit , Siripaitoon Pisud , Kositpantawong Narongdet , Kanchanasuwan Siripen , Aiewruengsurat Duangkamol , Bintachitt Piyawat , Charoenmak Boonsri , Jullangkoon Monchana , Chusri Sarunyou 
Published: April 2024

ABSTRACT.
Melioidosis is a potentially fatal infection caused by the bacterium Burkholderia pseudomallei. Septic arthritis caused by this infection is uncommon and difficult to treat. The role of adjunctive open arthrotomy in this type of infection has not yet been elucidated. We conducted a retrospective study of patients with microbiologically confirmed melioidosis between January 2002 and December 2022. Patients with a clinical condition of septic arthritis and positive cultures for B. pseudomallei were included. Comparisons were made between patients who received adjunctive therapy with open arthrotomy with conventional standard treatment and those who did not in terms of clinical outcomes and hospital expenditures. Of the 478 patients diagnosed with melioidosis microbiological confirmation, 81 patients had septic arthritis, accounting for 17% of cases. Among these patients, only 36 (44%) underwent adjunctive therapy with open arthrotomy. The 14-day and 30-day in-hospital mortality and length of hospital stays of patients who underwent adjunctive therapy with open arthrotomy were more favorable than those of patients who did not receive adjunctive therapy with open arthrotomy; however, the difference was not statistically significant. Patients who underwent adjunctive therapy with open arthrotomy had lower hospital expenditures (antimicrobial and non-antimicrobial costs) than those who did not undergo open arthrotomy. Adjunctive therapy with open arthrotomy for patients with septic arthritis due to melioidosis was associated with favorable clinical outcomes and significantly lower hospital expenditures.
Penentuan Zona Produktif Berdasarkan Parameter Mud Logging Unit Sumur DVS-04 Lapangan Jatibarang Pt Mustika Petrotech Indonesia
Authors: Winarto Winarto , Setiawan Guntur , Kusrini Desi , Putra Ananda Setiawan Davis 
Published: April 2024

Mud Logging Unit merupakan unit yang digunakan dalam pemantauan informasi dari cutting yang terbawa sirkulasi lumpur pemboran. Laporan Tugas Akhir ini memiliki tujuan, yaitu: menentukan keberadaan zona produktif (Payzone) berdasarkan parameter pemboran sumur DVS-04, mengetahui payzone dengan analisis cutting, Mengidentifikasi jenis hidrokarbon pada 2 payzone berdasarkan kalkulasi GWR, LRH dan OCQ. Parameter yang digunakan pada penentuan payzone, yaitu WOB, ROP, Total Gas Detector, Gas Chromatograph, Analisis Cutting, Kalkulasi GWR, LHR dan OCQ. Zona produktif (Payzone) adalah batuan reservoir yang mengandung fluida dalam jumlah yang bisa dieksploitasi, pada umumnya terletak pada lapisan permeable. Data yang digunakan ketika analisis payzone yaitu: ROP, WOB, total gas detector, gas chromatograph (C1- C5), Final Well Report dan Mud Log. Stratigrafi lapangan terdiri dari formasi cisubuh, formasi parigi, formasi cibulakan atas, formasi baturaja, formasi talangakar, dan formasi jatibarang, pada program pemboran sumur DVS-04 menargetkan payzone, yaitu pada formasi cibulakan atas. Setelah plotting didapat hasil perhitungan 2 payzone pada kedalaman 1363-1397 mMD dan 1505 – 1540 mMD pada batupasir dan batugamping. Payzone A dan payzone B memiliki nilai GWR 37.72 (Payzone A) dan 24.28 (Payzone B) pada kisaran 17,5-40 yang mengidentifikasikan zona mengandung minyak dengan GWR lebih besar dari pada LHR. Kedua payzone A dan B pada analisis cutting dan oil show menghasilkan informasi terkandungnya hidrokarbon kedua batuan produktif, yaitu batupasir dan batugamping. Pada analisis berdasarkan data secara terperinci, Payzone terbaik adalah payzone B terdapat di kedalaman 1505 – 1540 meter pada formasi cibulakan atas
Nivel de estrés y prescripción de medicamentos ansiolíticos en el adulto mayor post-pandemia en la ciudad de Huancayo. 2023
Authors: Lavado Morales Ivar Jines , Zevallos Falcon Karol Paola , Calle Vilca Mónica Alejandra , Zacarias Flores Mitzy 
Published: April 2024

Objetivo: Determinar el nivel de estrés y prescripción de medicamentos ansiolíticos en el adulto mayor post pandemia en la Ciudad de Huancayo. 2023. Material y Métodos: Estudio descriptivo, diseño no experimental y de corte transversal. Población total 4250 adultos mayores y la muestra de 352 adultos mayores. Resultados: El nivel de estrés del adulto mayor post pandemia en la ciudad de Huancayo, se encontró de acuerdo a la escala EEP-10, el nivel de estrés alto con 1,84. Determinado, a un Alfa de Cronbach = 0,828 y a un nivel de significancia α ˂ 0,05. La frecuencia de la edad de 61-69 prevalece en un 33,5 %. El sexo de los encuestados prevalece el femenino. En cuanto a la condición laboral, mayormente se dedican a la agricultura, jubilados y trabajadores independientes. Los medicamentos ansiolíticos más utilizados son el clonazepam, alprazolam y diazepam. Los medicamentos ansiolíticos modificaron su sensación en el paciente: la fatiga, depresión y apatía. La prescripción para el consumo de los ansiolíticos fue por un médico. Conclusiones: El nivel de estrés del adulto mayor fue un nivel de estrés alto, el sexo femenino prevalece con mayor estrés, la prescripción fue por un médico. El ansiolítico más utilizado es el clonazepam.
Estados de Arte e Temporalidades Incomuns: arte pública na via UERJ/Mangueira
Authors: Frade Isabela , Puga Jonatas Martin 
Published: April 2024

Na interação dialógica entre universidade e favela se fundamentam processos experimentais de comunalidade. A universidade, promotora de reflexões e ações, fomenta a própria comunidade acadêmica e seu entorno, como a Mangueira, na proposição de práticas estéticas efêmeras em formas presenciais. Os encontros se desdobram por multiplicidades heterotópicas. Passagens, escadas, casas, platôs e jardins emergem em deslocamentos espaço-temporais por situações de arte: tráfego de tempos variados, heterocronias em associações de sujeitos diversos por temporalidades múltiplas.
Espelhos Paralelos: passagens, trocas, reescritas e reconstruções de imagens
Authors: Rauscher Beatriz 
Published: April 2024

“Parallel mirrors” é um conjunto de trabalhos em processo, que reúne imagens criadas a partir da passagem por processos fotográficos e digitais. Este artigo relaciona alguns problemas teóricos que dele emergem para buscar os limites entre o que podemos chamar de fotografia e aqueles artefatos iconográficos que não temos propriamente uma palavra para definir. O termo “espelhos paralelos”, escolhido para nomear a série, foi adotado a partir da ideia do deslocamento do referente resultante da apropriação de imagens e sua submissão às operações poéticas do cruzamento, edição e remixagem.
Santiago Sierra - "Estética Remunerada"
Authors: Grando Angela 
Published: April 2024

No título deste artigo, o termo “estética remunerada” pretende abordar as condições do acontecimento de uma modalidade da obra do artista espanhol Santiago Sierra. Nesse eixo, propomos uma reflexão sobre as permeabilidades entre sua prática artística e propostas participativas na arte contemporânea.
Babel TV - Homenagem a Nam June Paik
Authors: Mèredieu Florence de 
Published: April 2024

1Esta texto de “ficção-teórica” toma por matriz e ponto de partida a Biblioteca de Babel, de Jorge Luis Borges. Ele se encaixa na esteira de um conjunto de 12 remarcações reunidas em um volume (Borges & Borges illimited, Paris, Blusson, 1986), seguido por novas “remarcações” (Trafic, FUROR, Genève, 1997, Duchampen forme de readymade, Paris, Blusson, 2000 e Babel /UQAM devaneio dedicado à obra de um jovem artista de Quebec, Stéphane Gilot, em Model Worlds, catálogo, Galeria da UQAM, Montreal, 2012).
A Moldura Literária no Texto-Tela Não Entres Tão Depressa Nessa Noite Escura, de António Lobo Antunes
Authors: Souza Aline Prúcoli de 
Published: April 2024

Com base no livro-poema Não entres tão depressa nessa noite escura, do escritor português António Lobo Antunes, relacionamos a literatura e a pintura, procurando entender especificamente a funcionalidade da moldura, elemento arbitrariamente delimitador, no trabalho de composição pictórico e discursivo. Realizamos, em outras palavras, uma análise homológica a partir da tentativa de “transposição” desse elemento da tela de pintura para a obra literária. Nosso objetivo éampliar o potencial semântico da leitura ao analisarmos os Paratextos Editoriais à luz da teoria das artes ditas plásticas, especialmente da Pintura - em sua dimensão material mais tradicional. Realizamos, portanto, uma pequena associação entre os dois gêneros artísticos - Literatura e Pintura - a partir do atual contexto das relações interartes.
Espírito Oitenta
Authors: Barreto Waldir 
Published: April 2024

Embora a década de 1980 surja, no âmbito da crítica de arte, como uma questão eminentemente alemã, a sua iminência, no âmbito da produção artística, seguida por uma polêmica teórica associada, surge também como um fenômeno caracteristicamente norte-americano, italiano e brasileiro. Para além de mera tendência reativa ao experimentalismo e ao conceitualismo das décadas anteriores,significou uma decisiva ruptura geracional, não apenas metodológica, senão paradigmática com a lógica moderna da arte. O rastreamento crítico-analítico deste rompimento no Espírito Santo é imperativo.
Le royaume des ombres Art et spectralité dans l’Esthétique de Hegel
Authors: Kirchmayr Raoul 
Published: April 2024

Est-il possible de dire que l’art est mort? Est-il encore possible de le dire alors que pour le Savoir Absolu, pour autant qu’il en reste quelque chose, sonne le glas ? Littéralement parlant, Hegel n’a jamais prononcé ce constat de mort, bien que le motif de la mort de l’art se soit constamment immiscé dans une idéologie de la fin, qui s’est présentée comme un diagnostic sur l’Occident. Un diagnostic formulé dans les termes d’une description d’un déclin accompli, dont il fallait reconnaître les signes, ou bien, au contraire et par optimisme, d’un signe qui a scellé une époque révolue, en manifestant ainsi sa vérité. Au pire, associer le thème de la mort de l’art à l’esthétique de Hegel est devenu un locus communis conservateur, au nom d’un sens de l’art qui serait allé se perdre dans la crise de notre temps. Au mieux, il est devenu une occasion pour réfléchir sur le statut incertain de l’art aujourd’hui et sur les disciplines qui se sont légitimé comme autant de savoirs sur l’art, au nom d’un discours qui se veut scientifique, in primis l’histoire de l’art aussi bien que, plus récemment, la sémiologie, dont le trajet, d’ailleurs heureux, est désormais achevé. [...]