bluuebunny/crossref_metadata_2025_split huggingface dataset:
SARS‐CoV‐2 infection among psoriasis patients in Germany: Data from the German registries PsoBest and CoronaBest
Authors: López María José Valencia , Meineke Anna , Stephan Brigitte , Rustenbach Stephan Jeff , Kis Anne , Thaçi Diamant , Mrowietz Ulrich , Reich Kristian , Staubach‐Renz Petra , von Kiedrowski Ralph , Bogena Henriette , Augustin Matthias 
Published: May 2024

SummaryBackgroundLimited data exist on the characteristics of SARS‐CoV‐2 infections in German patients with psoriasis or psoriasis arthritis (PsA). This study analyses COVID‐19 prevalence and severity of symptoms in these patients.Patients and MethodsParticipants of the German registries PsoBest and CoronaBest were surveyed in February 2022. Descriptive analyses were conducted.Results4,818 patients were included in the analysis, mean age of 56.4 years. Positive SARS‐CoV‐2 tests were reported by 737 (15.3%) patients. The most frequently reported acute symptoms were fatigue (67.3%), cough (58.8%), and headache (58.3%). Longer‐lasting symptoms after COVID‐19 were reported by 231 of 737 patients after the acute phase. For most patients (92.9%), systemic treatment for their psoriasis or PsA was not modified during the pandemic. Patients positively tested for SARS‐CoV‐2 were younger on average and had more often changes in the therapy of psoriasis than negatively tested patients (8.5% vs. 5.4%).ConclusionsIn this cohort of patients with psoriasis or PsA undergoing systemic treatment, SARS‐CoV‐2 infections were common but less frequent than in the general German population. No risk signals for more severe COVID‐19 or increased infection rates were observed in the patients. In addition, systemic treatments remained largely unchanged, so that no risks can be attributed to these therapies.
Dieback of small‐leaved lime trees (Tilia cordata Mill.) caused by Gibsiella quercinecans in urban areas in Poland
Authors: Tkaczyk Miłosz , Sikora Katarzyna , Plewa Radosław 
Published: May 2024

AbstractIn the summer of 2023, small‐leaved lime trees (Tilia cordata) in the capital city of Warsaw were found to be dying along transport routes. The stem fragments collected for analysis showed the presence of necrosis near larval galleries caused by Agrilus viridis (L.). After a detailed microbiological analysis of both the tissues taken directly from the necroses and from the larval galleries, the presence of five different bacteria was confirmed, including Gibsiella quercinecans, which is responsible for the phenomenon of oak stand dieback known as Acute Oak Dieback. The pathogenicity tests carried out confirmed that this bacterium is also capable of causing necrosis on lime trees. The fact that this bacterium was found in the larval galleries of the polyphagous A. viridis could also indicate that it was vectored into the lime tree from other species, for example, oaks. The results obtained are the first report on the occurrence of G. quercinecans on lime trees in Poland.
Multimodal imaging investigation of structural rich club alterations in Alzheimer's disease and mild cognitive impairment: Amyloid deposition, structural atrophy, and functional activation differences
Authors: Markett Sebastian , Boeken Ole J. , Wudarczyk Olga A. ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: May 2024

AbstractAlzheimer's disease (AD) is characterized by significant cerebral dysfunction, including increased amyloid deposition, gray matter atrophy, and changes in brain function. The involvement of highly connected network hubs, known as the “rich club,” in the pathology of the disease remains inconclusive despite previous research efforts. In this study, we aimed to systematically assess the link between the rich club and AD using a multimodal neuroimaging approach.We employed network analyses of diffusion magnetic resonance imaging (MRI), longitudinal assessments of gray matter atrophy, amyloid deposition measurements using positron emission tomography (PET) imaging, and meta‐analytic data on functional activation differences. Our study focused on evaluating the role of both the structural brain network's core and extended rich club regions in individuals with mild cognitive impairment (MCI) and those diagnosed with AD.Our findings revealed that structural rich club regions exhibited accelerated gray matter atrophy and increased amyloid deposition in both MCI and AD. Importantly, these regions remained unaffected by altered functional activation patterns observed outside the core rich club regions. These results shed light on the connection between two major AD biomarkers and the rich club, providing valuable insights into AD as a potential disconnection syndrome.
Quantifying aboveground biomass, soil organic carbon and erosion with a detailed crop map and PESERA model in the Yangtze River Basin
Authors: Zhou Jichen , Baartman Jantienne , Ning Yinan , Nunes João Pedro , van Delden Hedwig , Vanhout Roel , Chen Xinping , Ritsema Coen , Ma Lihua , Liu Xuejun 
Published: May 2024

AbstractSoil erosion represents a primary threat to soil systems with adverse implications for ecosystem services, crop production, potable water and carbon storage. While numerous studies have quantified the spatial distribution of aboveground Biomass (AGB), soil erosion and soil organic carbon (SOC) in the Yangtze River Basin (YRB), limited attention has been given to assessing the contributions of different land use types and especially crop types to AGB, soil erosion and SOC. In most studies, cropland is taken as a land use class, while detailed crop types and rotation patterns, and their effect on soil erosion and SOC, vary significantly. In this study, we used the Metronamica model to generate a detailed crop rotation and distribution map across the YRB and subsequently employed the Pan‐European Soil Erosion Risk Assessment (PESERA) model to simulate the spatial distribution of AGB, soil erosion and SOC on a monthly basis. PESERA model simulations indicate an average soil erosion rate across the entire YRB of 7.7 ton/ha/yr, with erosion hotspots concentrated in the Sichuan Basin and the central‐southern regions. The southwestern region and western Sichuan show elevated levels of AGB and SOC, while the eastern plains display lower levels. Erosion rates are lowest in areas designated as artificial land, pasture and grassland, whereas croplands and fruit tree plantations experience the highest erosion rates. In terms of crop types, the highest erosion rates and lowest AGB are observed under fallow and potato cultivation, while the lowest erosion rates and highest AGB are found in rice‐wheat rotation fields. To the best of our knowledge, this is the first study taking detailed crop types and patterns into account while evaluating their effect at a relatively large scale (i.e., YRB). These findings can help to develop sustainable soil management and (cropping) conservation strategies.
Cultural values and voice as determinants of customers' marketing research cooperation: A fuzzy set perspective
Authors: Osakwe Christian Nedu , Ogunmokun Oluwatobi A. , Adeola Ogechi , Jibril Abdul Bashiru 
Published: May 2024

AbstractFirms and their managers have long been concerned with encouraging customers to take on an active role in their marketing research activities. The critical question for these firms is how to foster collaboration with customers in marketing research to enhance the firm's marketing effectiveness and simultaneously benefit the customers. This study focuses on the role that individuals' cultural values and customer voice potentially play in shaping how customers perceive marketing research cooperation with the firm. We analyzed data from a sample of 270 customers of apparel store brands in an African country. Utilizing fuzzy‐set qualitative comparative analysis, our research reveals that the combinations of antecedent conditions that enhance marketing research cooperation significantly differ from those that impede it. Theoretically and managerially, our study expands the understanding of how marketing research cooperation is contingent upon the combination of customers' cultural values and their voice.
Low‐temperature co‐fired ceramic application of SmTaO4 and YTaO4 with ZnO‐B2O3‐SiO2 additive
Authors: Yang Hongcheng , Huang Xier , Zhang Jin , Li Enzhu 
Published: May 2024

AbstractIn this study, ZnO‐B2O3‐SiO2 (ZBS) glass was employed as a sintering facilitator, enabling low‐temperature sintering of SmTaO4 and YTaO4 ceramics. The influence of varying quantities of ZBS glass on sintering behavior and phase composition was investigated to reveal the low‐temperature sintering mechanism. ZBS glass exhibits favorable wetting behavior on the SmTaO4 and YTaO4 ceramic matrices and dramatically decreases the initial shrinkage temperature of ceramics throughout the sintering process. Composited with 20 wt. % ZBS and sintered at their optimal sintering temperature, the composite ceramics of SmTaO4 and YTaO4 possess favorable microwave dielectric properties: εr = 8.46, Q×f = 15,723 GHz, and τf = –6.68 ppm/°C (at 14.339 GHz), and εr = 4.21, Q×f = 18,939 GHz, and τf = –18.92 ppm/°C (at 15.512 GHz), respectively.
Unveiling the role of the KLF4/Lnc18q22.2/ULBP3 axis in the tumorigenesis and immune escape of hepatocellular carcinoma under hypoxic condition
Authors: Wei Lifang , He Ping , Tan Zhongqiu , Zhao Lifeng , Lin Cheng , Wei Zhongheng 
Published: May 2024

AbstractHepatocellular carcinoma (HCC) represents a significant global health burden, necessitating an in‐depth exploration of its molecular underpinnings to facilitate the development of effective therapeutic strategies. This investigation delves into the complex role of long non‐coding RNAs (lncRNAs) in the modulation of hypoxia‐induced HCC progression, with a specific emphasis on delineating and functionally characterizing the novel KLF4/Lnc18q22.2/ULBP3 axis. To elucidate the effects of hypoxic conditions on HCC cells, we established in vitro models under both normoxic and hypoxic environments, followed by lncRNA microarray analyses. Among the lncRNAs identified, Lnc18q22.2 was found to be significantly upregulated in HCC cells subjected to hypoxia. Subsequent investigations affirmed the oncogenic role of Lnc18q22.2, highlighting its critical function in augmenting HCC cell proliferation and migration. Further examination disclosed that Kruppel‐like factor 4 (KLF4) transcriptionally governs Lnc18q22.2 expression in HCC cells, particularly under hypoxic stress. KLF4 subsequently enhances the tumorigenic capabilities of HCC cells through the modulation of Lnc18q22.2 expression. Advancing downstream in the molecular cascade, our study elucidates a novel interaction between Lnc18q22.2 and UL16‐binding protein 3 (ULBP3), culminating in the stabilization of ULBP3 protein expression. Notably, ULBP3 was identified as a pivotal element, exerting dual functions by facilitating HCC tumorigenesis and mitigating immune evasion in hypoxia‐exposed HCC cells. The comprehensive insights gained from our research delineate a hitherto unidentified KLF4/Lnc18q22.2/ULBP3 axis integral to the understanding of HCC tumorigenesis and immune escape under hypoxic conditions. This newly unveiled molecular pathway not only enriches our understanding of hypoxia‐induced HCC progression but also presents novel avenues for therapeutic intervention.
An overview of the different digital facebow methods for transferring the maxillary cast into the virtual articulator
Authors: Revilla‐León Marta , Zeitler Jonathan M. , Kois John C. 
Published: May 2024

AbstractObjectivesThe purposes of this study were to classify the described digital facebow techniques for transferring the maxillary cast into the semi‐adjustable virtual articulator based on the digital data acquisition technology used and to review the reported accuracy values of the different digital facebow methods described.OverviewDigital data acquisition technologies, including digital photographs, facial scanners, cone beam computed tomography (CBCT) imaging, and jaw tracking systems, can be used to transfer the maxillary cast into the virtual articulator. The reported techniques are reviewed, as well as the reported accuracy values of the different digital facebow methods.ConclusionsDigital photographs can be used to transfer the maxillary cast into the virtual articulator using the true horizontal reference plane, but limited studies have assessed the accuracy of this method. Facial scanning and CBCT techniques can be used to transfer the maxillary cast into the virtual articulator, in which the most frequently selected references planes are the Frankfort horizontal, axis orbital, and true horizontal planes. Studies analyzing the accuracy of the maxillary cast transfer by using facial scanning and CBCT techniques are restricted. Lastly, optical jaw trackers can be selected for transferring the maxillary cast into the virtual articulator by using the axis orbital or true horizontal planes, yet the accuracy of these systems is unknown.Clinical ImplicationsDigital data acquisition technologies, including digital photographs, facial scanning methods, CBCTs, and optical jaw tracking systems, can be used to transfer the maxillary cast into the virtual articulator. Studies are needed to assess the accuracy of these digital data acquisition technologies for transferring the maxillary cast into the virtual articulator.
Political Uncertainty and the Geographic Allocation of Credit: Evidence from Small Businesses
Authors: CERQUEIRO GERALDO , MÃO‐DE‐FERRO ANA , PENAS MARÍA FABIANA 
Published: May 2024

AbstractWe investigate how banks change the geographic distribution of their small business loan portfolio when they face political uncertainty in some of the states where they operate. Using exogenous variation in gubernatorial elections with binding term limits, we show that political uncertainty causes local banks to increase out‐of‐state lending to small firms, particularly those located in higher‐income areas. This effect follows a decrease in local lending and is stronger for banks that are more capital‐constrained. The increase in out‐of‐state credit leads to an increase in employment growth and net firm creation in sectors with larger capital needs.
Insight into the evolution of textural properties and juiciness of ready‐to‐eat chicken breasts upon different thermal sterilization: From the perspective of protein degradation
Authors: Liu Xiaoyan , Zhou Kai , Chen Bo , Xie Yong , Ma Yunhao , Zhou Hui , Xu Baocai 
Published: May 2024

AbstractTexture deterioration of meat products upon high‐temperature sterilization is a pressing issue in the meat industry. This study evaluated the effect of different thermal sterilization temperatures on the textural and juiciness of ready‐to‐eat (RTE) chicken breast. In this study, by dynamically monitoring the texture and juiciness of chicken meat products during the process of thermal sterilization, it has been observed that excessively high sterilization temperatures (above 100°C) significantly diminish the shear force, springiness and water‐holding capacity of the products. Furthermore, from the perspective of myofibrillar protein degradation, molecular mechanisms have been elucidated, unveiling that the thermal sterilization treatment at 121°C/10 min triggers the degradation of myosin heavy chains and F‐actin, disrupting the lattice arrangement of myofilaments, compromising the integrity of sarcomeres, and resulting in an increase of approximately 40.66% in the myofibrillar fragmentation index, thus diminishing the quality characteristics of the products. This study unravels the underlying mechanisms governing the dynamic changes in quality of chicken meat products during the process of thermal sterilization, thereby providing theoretical guidance for the development of high‐quality chicken products.
Courts and democratic backsliding: A comparative perspective on the United States
Authors: Gardbaum Stephen 
Published: May 2024

AbstractThis article argues that courts in the United States are comparatively less likely to be captured than those of many other countries and more able to resist an authoritarian populist regime, but also somewhat more likely to facilitate democratic backsliding on their own account. In this way, they potentially could—and arguably already do—provide a relatively rare case of “abusive judicial review” by independent courts. The article also briefly considers whether the US experience provides any insights for the relationship of courts and democratic backsliding in other countries, and especially how the ability of courts to resist capture might be bolstered.
Serum bile acid change correlates with improvement in pruritus in patients with primary biliary cholangitis receiving linerixibat
Authors: Karatza Eleni , Swift Brandon , Carreño Fernando , Mukherjee Sumanta , Casillas Linda , Lennie Janelle , Fettiplace James , McLaughlin Megan M. , Kremer Andreas E. 
Published: May 2024

AbstractBackground & AimsTotal serum bile acid (TSBA) levels are elevated in patients with primary biliary cholangitis (PBC) and may mediate cholestatic pruritus. Linerixibat, an ileal bile acid transporter inhibitor, improved pruritus in patients with PBC. We explored the relationship between linerixibat dose, TSBA concentration, and pruritus.MethodsData from Phase 1/2 trials were used to develop a population kinetic‐pharmacodynamic model to characterize the linerixibat dose–TSBA relationship. Individual Bayesian parameter estimates for participants in the GLIMMER study were used to derive the area under the TSBA concentration curve over 24 h (AUC0–24). Time‐matched post hoc estimates of AUC0–24 were correlated with pruritus reported on a 0–10 numerical rating scale. Baseline TSBA concentration was correlated with change from baseline (ΔBL) in monthly itch score (MIS). ΔBL in model‐estimated TSBA AUC0–24 was correlated with time‐matched ΔBL in weekly itch score (WIS) or MIS.ResultsLinerixibat dose dependently reduced TSBA AUC0–24, reaching steady state after 5 days. Baseline TSBA levels in GLIMMER did not correlate with ΔBL in MIS. ΔBL in TSBA AUC0–24 correlated with improved WIS over 12 weeks of treatment (r = 0.52, p < 0.0001). Of participants with a ≥30% decrease in TSBA AUC0–24, 60% were pruritus responders (≥2‐point improvement in WIS from baseline).ConclusionsLinerixibat treatment leads to rapid, dose‐dependent TSBA reductions. Baseline TSBA levels do not correlate with on‐treatment pruritus change, suggesting they do not predict linerixibat response. Change in TSBA AUC0–24 correlates significantly with, and can be predictive of, pruritus improvement in patients with PBC.
Protective effect of equol intake on bladder dysfunction in a rat model of bladder outlet obstruction
Authors: Miyazaki Nozomu , Katsura Ryota , Ozaki Chiaki , Suzutani Tatsuo 
Published: May 2024

AbstractObjectivesThis study evaluates the impact of equol, a metabolite of soy isoflavone, on bladder dysfunction in rats with bladder outlet obstruction (BOO). In addition, we investigate its potential as a neuroprotective agent for the obstructed bladder and discuss its applicability in managing overactive bladder (OAB).MethodsEighteen male Sprague–Dawley rats were divided into three groups (six rats per group) during the rearing period. The Sham and C‐BOO groups received an equol‐free diet, while the E‐BOO group received equol supplementation (0.25 g/kg). At 8 weeks old, rats underwent BOO surgery, followed by continuous cystometry after 4 weeks of rearing. The urinary oxidative stress markers (8‐hydroxy‐2′‐deoxyguanosine and malondialdehyde) were measured, and the bladder histology was analyzed using hematoxylin–eosin, Masson's trichrome, and immunohistochemical staining (neurofilament heavy chain for myelinated nerves, peripherin for unmyelinated nerves, and malondialdehyde).ResultsEquol reduced BOO‐induced smooth muscle layer fibrosis, significantly prolonged the micturition interval (C‐BOO: 193 s, E‐BOO: 438 s) and increased the micturition volume (C‐BOO: 0.54 mL, E‐BOO: 1.02 mL) compared to the C‐BOO group. Equol inhibited the increase in urinary and bladder tissue malondialdehyde levels. While the C‐BOO group exhibited reduced peripherin alone positive nerve fibers within the smooth muscle layer, equol effectively attenuated this decline.ConclusionsEquol reduces lipid peroxidation and smooth muscle layer fibrosis in the bladder and exhibited neuroprotective effects on bladder nerves (peripheral nerves) and prevented the development of bladder dysfunction associated with BOO in rats. Consumption of equol is promising for the prevention of OAB associated with BOO.
Forecasting Inflation with the New Keynesian Phillips Curve: Frequencies Matter*
Authors: Martins Manuel M. F. , Verona Fabio 
Published: May 2024

AbstractWe forecast US inflation with a new Keynesian Phillips curve (NKPC) in the frequency domain. Our method consists of decomposing the time series of inflation and its NKPC predictors into several frequency bands, forecasting separately each frequency component of inflation, and then summing up those forecasts to obtain the forecast for aggregate inflation. We find that (i) accurately forecasting the low frequency of inflation is, on average, crucial to successfully forecast inflation; (ii) our NKPC low‐frequency forecast model consistently and significantly outperforms the time‐series NKPC and standard benchmark models; (iii) the low frequencies of inflation expectations and unemployment are the key predictors; and (iv) optimally switching on / off the forecasts of each frequency components of inflation at each period allows to outstandingly track inflation and show that all frequencies of inflation matter.
Peritendinous Submembrane Access Technique for Management of Acute Ruptures of the Achilles Tendon: A Retrospective Study of 249 Cases
Authors: Huang Xin , Liu Jia‐Wei , Jiang Yu , Zhu Hong‐Wei , Hu Xing‐Xing , Wu Ke‐Jian , Wang Xiao‐Ning , Zhang Shuai 
Published: May 2024

ObjectivePercutaneous repair is an alternative to open surgical repair of the Achilles tendon with comparable, functional results and low re‐rupture and infection rates; however, sural nerve injury is a known complication. The purpose of this study is to design a new surgical procedure, the minimally invasive peritendinous submembrane access technique (MIS‐PSAT). It offers optimal results, with excellent functional outcomes, and with minimal soft tissue complications and sural nerve injury.MethodsThis retrospective study included 249 patients with acute closed Achilles tendon ruptures treated at our institution between 2009 and 2019. All patients underwent MIS‐PSAT at our institution and were followed up for 8–48 months. Functional evaluation was based on the Achilles tendon total rupture score (ATRS) and the American Orthopedic Foot and Ankle Society Ankle‐Hindfoot Scale (AOFAS‐AHS), associated with local complications and isokinetic tests.ResultsNone of the patients had infection, necrosis, or sural nerve injury. Re‐rupture occurred in two cases. The average times to return to work and sports was 10.4 and 31.6 weeks, respectively. The average ATRS and AOFAS‐AHS scores were 90.2 and 95.7, respectively, with an excellent rate of 99.5%. Isokinetic tests showed that ankle function on the affected side was comparable with that on the healthy side (p > 0.05).ConclusionThe MIS‐PSAT for acute Achilles tendon rupture is easy to perform with few complications. Importantly, the surgical technique reduces the risk of sural nerve injuries. Patients have high postoperative satisfaction, low re‐rupture rates, and muscle strength, and endurance can be restored to levels similar to those on the healthy side.