bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of arytenoid asymmetry in relation to vocal symptoms
Authors: Hamdan A-L , Nassar J , Ashkar J , Sibai A 
Published: December 2010

AbstractObjectives:(1) To assess the prevalence of arytenoid asymmetry during adduction, and (2) to correlate arytenoid asymmetry with vocal symptoms.Materials and method:The medical records and video recordings of 116 patients who presented to the voice clinic were reviewed for the presence of arytenoid asymmetry, as regards sharpening of the aryepiglottic fold angle and altered positioning of the cuneiform and corniculate cartilages.Results:There were 61 males and 55 females, with a mean age of 39 years and a standard deviation of 15 years. Almost one-third had a history of reflux, 25 per cent had a history of smoking and 9.6 per cent had a history of allergy. Hoarseness was the most common symptom, occurring in 42.2 per cent of patients, followed by vocal fatigue (25 per cent) and inability to project the voice. The most common type of asymmetry was corniculate asymmetry, present in 27.6 per cent of the cases and accounting for 74.39 per cent of cases. This was followed by cuneiform cartilage asymmetry, present in 15.5 per cent of cases. There was no correlation between arytenoid asymmetry and vocal symptoms, except for vocal fatigue (p = 0.038).Conclusion:The prevalence of arytenoid asymmetry during adduction is common. The presence of vocal symptoms such as hoarseness, breathiness, inability to project the voice and straining does not generally seem to correlate with the prevalence of arytenoid asymmetry. However, subjects with vocal fatigue are more likely to have cuneiform asymmetry.
The resolution of conflicts among competing systems: A bidirectional perspective
Authors: Gass Susan M. 
Published: December 2010

ABSTRACTThe present study investigates the interaction of syntax, semantics, and pragmatics from the perspective of functional constraints on sentence processing. The functionalist model of Bates and Mac-Whinney (1981a, 1987) is taken as a basis for investigating subjects' reactions to sentences in which word order, topic, and animacy are varied. Subjects were native speakers of Italian, a language which is sensitive to semantics for interpretation and English, a language which is sensitive to syntax for interpretation (Bates, McNew, MacWhinney, Devescovi, & Smith, 1982). The two native speaker groups were further subdivided in terms of second versus foreign language learners. This study focusses on the question of how learners move from one organizational system to another. It is argued that the ways in which L2 learners are able to determine the strength of dominant factors provides insights not only into the processes involved in L2 acquisition but also into the relative strength of components crosslinguistically and the strength of boundaries between linguistic and extra-linguistic information. The results suggest that in moving from a semantic-dominant language to a syntactic-dominant one, learners first become aware of the importance of the concept of word order in a second language before being able to determine the specifics of word order in that language. On the other hand, moving in the other direction (from syntactic to semantic dominance) seems to come about with greater ease. To account for these results, a prototype model of acquisition is introduced. Finally, differences between second language and foreign language-learning environments are discussed.
Processing transfer: Language-specific processing strategies as a source of interlanguage variation
Authors: Harrington Michael 
Published: December 2010

ABSTRACTA sentence interpretation experiment based on the functionalist Competition Model of speech processing (Bates & MacWhinney, 1982) was administered to three groups of university-age English L1, Japanese ESL, and Japanese L1 subjects (n = 12 per group) in an attempt to elicit evidence for (1) processing strategies characteristic of the Japanese and English L1 groups and, (2) transfer/influence of Japanese L1 strategies on the English sentence interpretations of the Japanese ESL group. Subjects selected the subject/actor of simple sentences incorporating word order, animacy, and stress cues in random converging and competing orders. The English L1 and ESL groups were tested on English sentences and the Japanese L1 group tested on Japanese sentences. The Japanese L1 interpretations were most heavily influenced by animacy cues, while the English L1 group showed a higher overall sensitivity to word order manipulations. The ESL group resembled the Japanese L1 group in reliance on animacy cues, with the exception of allowing inanimate nouns to act as subjects. While the ESL group showed greater sensitivity to word order effects than the Japanese L1 group, no “second-noun” strategy (i.e., systematically interpreting the NNV and VNN orders as left- and right-dislocated SOV and VOS orders) was evident.Although the findings were generally consistent with previous research, the presence of contrasting response patterns in the English L1 group suggests caution in attempting to typify languages on the basis of processing strategies drawn from probablistic tendencies evident in grouped data, and leaves open the role of such processing strategy typologies as a potential source of variation in inter-language.
A critical review of the literature on social and leisure activity and wellbeing in later life
Authors: ADAMS KATHRYN BETTS , LEIBBRANDT SYLVIA , MOON HEEHYUL 
Published: December 2010

ABSTRACTAn engaged lifestyle is seen as an important component of successful ageing. Many older adults with high participation in social and leisure activities report positive wellbeing, a fact that fuelled the original activity theory and that continues to influence researchers, theorists and practitioners. This study's purpose is to review the conceptualisation and measurement of activity among older adults and the associations reported in the gerontological literature between specific dimensions of activity and wellbeing. We searched published studies that focused on social and leisure activity and wellbeing, and found 42 studies in 44 articles published between 1995 and 2009. They reported from one to 13 activity domains, the majority reporting two or three, such as informal, formal and solitary, or productive versus leisure. Domains associated with subjective wellbeing, health or survival included social, leisure, productive, physical, intellectual, service and solitary activities. Informal social activity has accumulated the most evidence of an influence on wellbeing. Individual descriptors such as gender or physical functioning sometimes moderate these associations, while contextual variables such as choice, meaning or perceived quality play intervening roles. Differences in definitions and measurement make it difficult to draw inferences about this body of evidence on the associations between activity and wellbeing. Activity theory serves as shorthand for these associations, but gerontology must better integrate developmental and psychological constructs into a refined, comprehensive activity theory.
Law-making at the intersection of international environmental, humanitarian and criminal law: the issue of damage to the environment in international armed conflict
Authors: Wyatt Julian 
Published: December 2010

AbstractThe relationship between international environmental law and international humanitarian law, like relationships between many other subsystems of contemporary international law, has not yet been articulated. The problem of environmental damage in international armed conflict lies at the intersection of these two branches and thus provides an ideal opportunity to investigate this relationship. Rather than simply evaluating the applicable international law rules in their context, we break them into elements that we separately assess from both (international) environmental law and international humanitarian/international criminal law perspectives. By doing so, we identify how international law rules for cross-sectoral problems may appropriately combine the existing expertise and institutional strengths of simultaneously applicable branches of international law, and also discover how an evaluation of the ultimate appropriateness of the cross-sectoral rules adopted may be substantially affected by the different frames of reference that are used by those working within the different fields.
Science Education Policy: A Symposium
Authors: KUMAR DAVID D. , ALTSCHULD JAMES W. 
Published: December 2010

AbstractThis article introduces Science Education Policy: A Symposium. The symposium examines trends and issues from the vantage points of individuals from a variety of backgrounds who are concerned with science education in the US. Although optimistic, most of the contributors to this symposium agree that considerable research and evaluation is still needed before we can make informed policy decisions that would have a lasting impact on science education. The expected outcome of the symposium is to stimulate discussions among educators and policymakers.
Automated Surveillance of Clostridium difficile Infections Using BioSense
Authors: Benoit Stephen R. , McDonald L. Clifford , English Roseanne , Tokars Jerome I. 
Published: December 2010

Objective.To determine the feasibility of using electronic laboratory and admission-discharge-transfer data from BioSense, a national automated surveillance system, to apply new modified Clostridium difficile infection (CDI) surveillance definitions and calculate overall and facility-specific rates of disease.Design.Retrospective, multicenter cohort study.Setting.Thirty-four hospitals sending inpatient, emergency department, and /or outpatient data to BioSense.Methods.Laboratory codes and text-parsing methods were used to extract C. difficile-positive toxin assay results from laboratory data sent to BioSense during the period from January 1, 2007, through June 30, 2008; these were merged with administrative records to determine whether cases were community associated or healthcare onset, as well as patient-day data for rate calculations. A patient was classified as having hospital-onset CDI if he or she had a C. difficile toxin-positive result on a stool sample collected 3 or more days after admission and community-onset CDI if the specimen was collected less than 3 days after admission or the patient was not hospitalized.Results.A total of 4,585 patients from 34 hospitals in 12 states had C. difficile-positive assay results. More than half (53.0%) of the cases were community-onset, and 30.8% of these occurred in patients who were recently hospitalized. The overall rate of healthcare-onset CDI was 7.8 cases per 10,000 patient-days, with a range among facilities of 1.5-27.8 cases per 10,000 patient-days.Conclusions.Electronic laboratory data sent to the BioSense surveillance system were successfully used to produce disease rates of CDI comparable to those of other studies, which shows the feasibility of using electronic laboratory data to track a disease of public health importance.
Dissemination and Sustainability of a Hospital-Wide Hand Hygiene Program Emphasizing Positive Reinforcement
Authors: Mayer Jeanmarie , Mooney Barbara , Gundlapalli Adi , Harbarth Stephan , Stoddard Gregory J , Rubin Michael A. , Eutropius Louise , Brinton Britt , Samore Matthew H. 
Published: December 2010

Objective.To increase and sustain hospital-wide compliance with hand hygiene through a long-term ongoing multidimensional improvement program emphasizing behavioral factors.Design.Quasi-experimental short study (August 2000-November 2001) and descriptive time series (April 2003-December 2006).Setting.A 450-bed teaching tertiary-care hospital.Interventions.An initial intervention bundle was introduced in pilot locations that addressed cognitive behavioral factors, which included access to alcohol sanitizer, education, and ongoing audit and feedback. The bundle was subsequently disseminated hospital-wide, along with a novel approach focused on behavior modification through positive reinforcement and annually changing incentives.Results.A total of 36,123 hand hygiene opportunities involving all categories of healthcare workers from 12 inpatient units were observed from October 2000 to October 2006. The rate of compliance with hand hygiene significantly improved after the intervention in 2 cohorts over the first year (from 40% to 64% of opportunities and from 34% to 49% of opportunities;P< .001, compared with the control group). Mean compliance rates ranged from 19% to 41% of 4174 opportunities (at baseline), increased to the highest levels of 73%–84% of 6,420 opportunities 2 years after hospital-wide dissemination, and remained improved at 59%–81% of 4,990 opportunities during year 6 of the program.Conclusion.This interventional cohort study used a behavioral change approach and is one of the earliest and largest institution-wide programs promoting alcohol sanitizer from the United States that has shown significant and sustained improvements in hand hygiene compliance. This creative campaign used ongoing frequent audit and feedback with novel use of immediate positive reinforcement at an acceptable cost to the institution.
Determination of electron density and temperature in a capacitively coupled RF discharge in neon by OES complemented with a CR model
Authors: Navrátil Z , Dvořák P , Brzobohatý O , Trunec D 
Published: December 2010

A method of determination of electron temperature and electron density in plasmas based on optical emission spectroscopy complemented with collisional–radiative modelling (OES/CRM) was studied in this work. A radiofrequency (13.56 MHz) capacitively coupled discharge in neon at 10 Pa was investigated by intensity calibrated optical emission spectroscopy. The absolute intensities of neon transitions between 3p and 3s states were fitted with a collisional–radiative (CR) model in order to determine the electron temperature and electron density. Measuring techniques such as imaging with an ICCD camera were adopted for supplementary diagnostics. The obtained results were compared with the results of compensated Langmuir probe measurement and one-dimensional particle-in-cell/Monte Carlo (PIC/MC) simulation.The results of OES/CRM and PIC/MC method were in close agreement in the case of electron temperature in the vicinity of a driven electrode. The determined value of electron temperature was about 8 eV. In bulk plasma, the measured spectra were not satisfactorily fitted. In the case of electron density only relative agreement was obtained between OES/CRM and Langmuir probe measurement; the absolute values differed by a factor of 5. The axial dependence of electron density calculated by PIC/MC was distinct from them, reaching the maximum values between the results of the other two methods. The investigation of power dependence of plasma parameters close to the driven electrode showed a decrease in electron temperature and an increase in electron density together with increasing incoming RF power. The calculated spectra fitted very well the measured spectra in this discharge region.
A study of the plasma electronegativity in an argon–oxygen pulsed-dc sputter magnetron
Authors: You S D , Dodd R , Edwards A , Bradley J W 
Published: December 2010

Using Langmuir probe-assisted laser photodetachment, the temporal evolution of the O− density was determined in the bulk plasma of a unipolar pulsed-dc magnetron. The source was operated in reactive mode, at a fixed nominal on-time power of 100 W, sputtering Ti in argon–oxygen atmospheres at 1.3 Pa pressure, but over a variation of duty cycles from 5% to 50% and oxygen partial pressures of 10% and 50% of the total pressure.
In the plasma on-time, for all duty cycles the negative ion density (n
−) rises marginally reaching values typically less than 2 × 1015 m−3 with negative ion-to-electron density ratios, α < 1. However, immediately after the transition from pulse on-to-off, n
− falls by about 20–30% as fast O− species created at the cathode exit the system. This is followed by a rapid rise in n
− to values at least 2 or 3 times that in the on-time. The rate of rise of n
− and its maximum value both increase with decreasing duty cycle. In the off-time, the electron density falls rapidly (initial decay rates of several tens of μs), and therefore the afterglow plasma becomes highly electronegative, with α reaching 4.6 and 14.4 for 10% and 50% oxygen partial pressure, respectively. The rapid rise in n
− in the afterglow (in which the electron temperature falls from about 5 to 0.5 eV) is attributed to the dissociative attachment of highly excited oxygen metastables, which themselves are created in the pulse on-time. At the lowest duty of 5%, the long-term O− decay times are several hundred μs.
Langmuir probe characteristics show the clear signature that negative ions dominate over the electrons in the off-time. From the ion and electron saturation current ratios, α has been estimated in some chosen cases and found to agree within a factor between 2 and 10 with those obtained more directly from the photodetachment method.
Baldness, acne and testicular germ cell tumours
Authors: Trabert B. , Sigurdson A. J. , Sweeney A. M. , Amato R. J. , Strom S. S. , McGlynn K. A. 
Published: December 2010

SummaryAndrogen levels during critical periods of testicular development may be involved in the aetiology of testicular germ cell tumours (TGCT). We evaluated the roles of adolescent and early adult life correlates of androgen exposure and TGCT in a hospital‐based case–control study. TGCT cases (n = 187) and controls (n = 148), matched on age, race and state of residence, participated in the study. Unconditional logistic regression was used to estimate associations between TGCT and male pattern baldness, severe acne, markers of puberty onset and body size. Cases were significantly less likely to report hair loss than controls [odds ratio (OR): 0.6; 95% confidence interval (CI): 0.4, 1.0]. Amount of hair loss, increasing age at onset and increasing rate of loss were all inversely associated with TGCT (rate of hair loss: p‐trend = 0.03; age at onset: p‐trend = 0.03; amount of hair loss: p‐trend = 0.01). History of severe acne was inversely associated with TGCT (OR: 0.5; 95% CI: 0.3, 0.9) and height was positively associated with TGCT (p‐trend = 0.02). Increased endogenous androgen levels during puberty and early adulthood may be associated with a decreased risk of TGCT. Additional studies of endogenous hormone levels during puberty and early adult life are warranted, especially studies evaluating the role of androgen synthesis, metabolism and uptake.
Osteoporosis in people with intellectual disabilities: a review and a brief study of risk factors for osteoporosis in a community sample of people with intellectual disabilities
Authors: Srikanth R. , Cassidy G. , Joiner C. , Teeluckdharry S. 
Published: December 2010

AbstractBackground The population of people with intellectual disabilities (ID) is increasing and their health needs impact on primary and secondary healthcare specialities. One important aspect of their physical health is bone health as people with ID have increased risk factors associated with osteoporosis. It has been identified that this population has an increased prevalence of low bone mineral density (BMD), osteoporosis and osteopenia. The main contributory factors for low BMD are age, use of antiepileptics, immobility and diagnosis of Down's syndrome.Methods A literature search of electronic databases was undertaken. Studies that included people with ID were reviewed for the prevalence of osteoporosis and osteopenia. A cross‐sectional survey was conducted in a community sample (n = 149) to screen for risk factors for osteoporosis.Results The majority of studies identified increased prevalence of osteoporosis and osteopenia with associated low BMD. In most studies individuals with ID presented with more than two risk factors. In our survey, we identified an increased prevalence of risk factors associated with osteoporosis, namely use of antiepileptics (64%), immobility (23%), history of falls (20%) and fractures (11%). We found that 54% of our sample fulfilled the criteria for screening. Of those who went on to have scans, 55% had osteoporosis and 33% had osteopenia.Conclusion We conclude that we should be screening for the risk factors associated with low BMD in adults with ID. If these are present further investigations should take place and those found to have osteoporosis and osteopenia should have treatment at an early stage to prevent morbidity and improve their quality of life.
Low mood and challenging behaviour in people with severe and profound intellectual disabilities
Authors: Hayes S. , McGuire B. , O'Neill M. , Oliver C. , Morrison T. 
Published: December 2010

AbstractBackground  We investigated the relationship between low mood and challenging behaviour in people in the severe and profound range of intellectual disability, while controlling for the presence of potentially confounding variables such as diagnosis of autism, physical and sensory problems and ill health.Methods  The key workers of 52 people with severe and profound intellectual disability completed measures of depression, communication, challenging behaviour and provided information on relevant demographic and health variables.Results  Using the Mood, Interest and Pleasure Questionnaire for classification of mood, a significant difference was found between a ‘low mood’ and ‘normothymic’ group in the reported occurrence of challenging behaviour. This difference remained even when confounding variables such as the presence of autism, health and sensory difficulties were controlled. The frequency and severity of challenging behaviour was predicted by measures indicating the presence of low mood.Conclusion  People with severe and profound show clear and measurable signs of low mood, and in this relatively small sample of institutionalised individuals, low mood was associated with challenging behaviour.
MALE GAMETOPHYTE DEFECTIVE 4 encodes a rhamnogalacturonan II xylosyltransferase and is important for growth of pollen tubes and roots in Arabidopsis
Authors: Liu Xiao‐Lei , Liu Lifeng , Niu Qian‐Kun , Xia Chuan , Yang Ke‐Zhen , Li Rui , Chen Li‐Qun , Zhang Xue‐Qin , Zhou Yihua , Ye De 
Published: December 2010

SummaryIn flowering plants, the growth of pollen tubes is essential for the delivery of sperm to the egg cells. Although many factors (including cell‐wall properties) are involved in this process, little is known about the underlying molecular mechanisms that regulate the growth of pollen tubes. We report here the characterization of an Arabidopsis mutant male gametophyte defective 4 (mgp4) that is severely defective in pollen tube growth. The mgp4 mutation also impairs root growth of pollen‐rescued mgp4 mutant plants generated by expressing MGP4 cDNA under the control of a pollen grain/tube‐specific promoter. The MGP4 gene encodes a putative xylosyltransferase and is expressed in many organs/tissues, including pollen tubes and roots. MGP4 protein expressed in Pichia pastoris exhibited xylosyltransferase activity and transferred d‐xylose onto l‐fucose. The pectic polysaccharide rhamnogalacturonan II (RG‐II), isolated from 7‐day‐old pollen‐rescued mutant seedlings, exhibited a 30% reduction in 2‐O‐methyl d‐xylose residues. Furthermore, an exogenous supply of boric acid enhanced RG‐II dimer formation and partially restored the root growth of the pollen‐rescued mutant seedlings. Taken together, these results suggest that MGP4 plays important roles in pollen tube and root growth by acting as a xylosyltransferase involved in the biosynthesis of pectic RG‐II.