bluuebunny/crossref_metadata_2025_split huggingface dataset:
Field prediction in urban environment using radar approach
Authors: Ouattara Yélakan B. , Richalot Elodie , Picon Odile , Wiart Joe 
Published: December 2010

AbstractTo accelerate radio channel predictions in urban environment, the use of the radar cross section is proposed as a compact representation of far‐field buildings scattering. Simple analytical formulas are obtained, and multiple scattering between buildings is taken into account by combining them with the ray‐tracing approach. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:257–261, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25726
Millimetre‐wave radio‐over‐fibre data transmission over multimode fibre
Authors: Khawaja Bilal A. , Cryan Martin J. 
Published: December 2010

AbstractThis article presents non‐return‐to‐zero (NRZ), binary phase‐shift keying (BPSK) data transmission over 100 m (50‐μm core) and 200 m (62.5‐μm core) millimetre‐wave multimode radio‐over‐fibre (RoF) links.The system consists of a 1.55‐μm tunable laser source, a wide bandwidth 40‐Gb/s Mach‐Zehnder Modulator (MZM), and a high‐speed photodiode for detection. Successful data transmission of 900 Mb/s over 100 m and 500 Mb/s over 200‐m multimode RoF links is achieved. A millimetre‐wave carrier frequency of 38.8 GHz is used for the data transmission over multimode fibres which is believed to the highest reported so far. After the RoF links eye‐diagrams are recovered with good Q‐factor performance recorded. These measurements show that multimode fibre links have the potential for use in next generation in‐building/campus wide pico‐cellular and low cost distributed antenna systems. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:254–256, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25727
Research on the electromagnetic scattering of 3D target coated with anisotropic medium using impedance boundary condition
Authors: Yu Ding‐Feng , He Si‐Yuan , Chen Hai‐Tao , Zhu Guo‐Qiang 
Published: December 2010

AbstractBased on impedance boundary condition, a method of moments solution for the electromagnetic scattering of three‐dimensional target coated with anisotropic medium is presented.According to the surface equivalence principle, the scatters can be replaced by equivalent electric and magnetic current source expanded by Rao‐Wilton‐Glisson vector‐basis functions. Using electric‐field integral equation, Galerkin moment method can deal with the electromagnetic issues of arbitrary structural targets (surface open or closed) simply and effectively. Electromagnetic parameters of medium are characterized by the surface impedance matrix, to simulate the anisotropic materials. Several numerical examples of typical target coated with anisotropic media are presented, and the results are compared with the physical optics solution, reasonable analysis is given as well. By setting the surface impedance matrix, the issue can be degraded to isotropic medium coating case or perfectly electric conductor case, and the proposed algorithm is still efficient and accurate. Simulation analysis to the electromagnetic scattering of plasma coating space satellite is presented, which provides theoretical support for the radar stealth and shows the proposed algorithm's value for engineering applications. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:458–462, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25728
A low‐voltage 5.4 GHZ monolithic cascode LNA using 0.18 um CMOS technology
Authors: Liu Baohong , Mao Junfa 
Published: December 2010

AbstractThis article presents a low‐voltage monolithic cascode LNA using 0.18‐um CMOS technology. Different from the stacked threshold voltage supply topology of conventional cascode LNA, this cascode LNA is designed as two cascaded stages for low‐voltage application. For the purpose of lowering the whole power dissipation while RF performances are not influenced, the current occupation is reduced by decreasing the channel width of the second NMOS. The whole circuit is implemented through TSMC 0.18‐um CMOS technology. Measurement results show that it can get 10.7‐dB gain and 2.6 dB NF at frequency of 5.4 GHz. The IIP3 is about −2.3 dBm. The supply voltage is only 0.7 V, and the whole power dissipation is 6.3 mW. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:386–389, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25733
Printed, multi‐loop‐antenna system integrated into a concurrent, dual‐WLAN‐band access point
Authors: Su Saou‐Wen , Hong Tzi‐Chieh 
Published: December 2010

AbstractA printed, planar multi‐loop‐antenna system having high‐gain, quasi‐dual‐polarized radiation properties for concurrent, dual‐band WLAN operation in the 2.4 and 5.2 GHz bands is presented. The multi‐antenna design comprises four printed loop antennas arranged to be of a orthogonal configuration, printed on the same‐layer of a 1.6‐mm thick FR4 substrate, and one system PCB serving as an efficient reflector for the loops. The four antennas are set within the boundary of the PCB of the typical size for compact, outdoor access‐point (AP) applications and stacked there above by a small distance. In this study, the design integrates the system PCB of an AP into an internal multi‐antenna solution for compact outdoor APs. The results show that good input matching with 10‐dB return loss over the 2.4 and 5.2 GHz bands can be attained. Directional radiation patterns with comparable Eθ and Eφ fields were also obtained. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:317–322, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25736
Improved test structure for on‐wafer microwave characterization of components
Authors: Descamps Philippe , Abessolo‐Bidzo Dolphin , Poirier Patrick 
Published: December 2010

AbstractThis article presents the impact of different test structures on the results of microwave characterization of on‐wafer components. In this study, we focus on the characterization and modeling of NXP Semiconductors Technology Passive Integration Connective Substrate (PICS) capacitor. First, we show the strong dependency of the extracted parameters according to test structure used when utilizing traditional open/short parasitic elements removing method. Second, we propose an optimization of the test structures to reduce their influence on the intrinsic parameters extracted from on‐wafer characterization of the device under test. We also propose a way to improve the accuracy of the modeling of PICS devices in radiofrequency and microwave domains. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:249–254, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25738
Design of a compact ultrawideband slot antenna with dual band‐notched function
Authors: Xue Jin‐Yuan , Gong Shu‐Xi , Fei Peng , Wang Wei , Zhang Fei‐Fei 
Published: December 2010

AbstractA compact ultrawideband (UWB) microstrip‐fed slot antenna with dual band‐notched function is presented.The prototype consists of an L‐shaped microstrip line, a modified ground plane with T‐shaped slot and a small stub embedded on the ground for impedance matching. The designed antenna satisfies the return loss requirement of larger than 10 dB in UWB frequency range from 3.1 to 10.6 GHz, whereas shows the wireless local area network and worldwide interoperability for microwave access band notched in the frequency band of 5.1–6 GHz and 3.5–4.1 GHz by the inserted rectangle strips. Detailed analysis and experimental results for the design are studied and investigated. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:245–249, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25739
A MIMO antenna with a two‐stage ground for USB dongle applications
Authors: Yu Yeonsik , Kim Giho , Seong Wonmo , Choi Jaehoon 
Published: December 2010

AbstractA multiband internal multiple‐input multiple‐output (MIMO) antenna for USB dongle applications is proposed. Two types of antenna element are used to construct a MIMO antenna system. The resonance frequencies of the MIMO antenna are controlled by the lengths of the two asymmetric arms or by the number of turns in a helix. The designed antenna provides wide bandwidth to cover LTE, DCN, and PCS‐1900 services, simultaneously. Although the MIMO antenna is installed within an electrically small USB dongle device, the isolation characteristic and antenna performance can be improved by using a two‐stage ground structure. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:418–422, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25742
Multimode broadband bandpass filter using one single square patch resonator
Authors: Xiao Zhongyin 
Published: December 2010

AbstractA novel multimode broadband square patch bandpass filter is proposed.The return loss of the filter is more than 11 dB and insertion loss is less than 1.2 dB within 3.47–5.22 GHz. This new filter has four transmission poles in the passband and the 3dB bandwidth is 48.9%. Measured results are in good agreement with simulated results. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:385–386, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25744
Design and analysis of a compact ultra‐wideband CMOS low‐noise amplifier
Authors: Seong Nackgyun , Jang Yohan , Choi Jaehoon 
Published: December 2010

AbstractIn this letter, we proposed a low power, high gain, compact ultra‐wideband (UWB) low noise amplifier (LNA) using TSMC 0.18‐μm CMOS technology.To satisfy the wide input matching and high voltage gain requirements with low power consumption, a resistive current reused technique is utilized. The proposed UWB LNA has a voltage gain of 10.4–15.5 dB and a noise figure (NF) of 3.3–4.5 dB over the frequency band of interest (1–8 GHz). The total power consumption of the proposed UWB LNA is 10.4 mW from a 1.4 V supply voltage, and the chip area is 0.8 mm × 0.5 mm. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:345–348, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25747
Design of simple CVTL bandstop filter
Authors: Hassan Essam E. M. , Sheikh Sharif I. , Al‐Sharif Yousef 
Published: December 2010

AbstractThe problem of microwave filters design using non‐uniform transmission line is tackled based on a global solution of the overall filter characteristics rather than localized characteristics. This technique simplifies the design process by significantly reducing the numerical efforts. A bandstop filter is designed using the proposed technique and optimized using genetic algorithm. The experimental results are presented and compared with the predicted response of the S‐band filter. Good agreement is found between the predicted and the experimental results. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:310–312, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25749
The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations
Authors: Brandow Amanda M. , Weisman Steven J. , Panepinto Julie A. 
Published: December 2010

AbstractBackgroundSickle cell disease (SCD) pain is acute or chronic, leads to school absenteeism, impaired health‐related quality of life and early mortality. Given that little is known about children with SCD and chronic pain, we (1) described characteristics of these children and (2) evaluated the impact of a multidisciplinary pain management model on health care utilization.ProcedureA retrospective cohort study of children with SCD evaluated and treated in our institution's multidisciplinary pain clinic between 1999 and 2008 was conducted. Referrals occur when children require chronic opioids and/or have frequent pain hospitalizations. Descriptive statistics evaluated patient characteristics and Wilcoxon‐Signed Rank evaluated change in median number of pain hospitalizations 1 year before and after referral.ResultsMedian age of 19 children identified was 15 years (IQR 11–17); significantly more were female (78.9% vs. 21.1%; P = 0.012). At time of referral, all patients reported taking opioids, 68.4% were taking hydroxyurea, half of those not on hydroxyurea started it (n = 3), none were chronically transfused and one initiated transfusions upon referral. Majority (89.5%) learned non‐pharmacologic pain management techniques. Median number of pain hospitalizations between the year before and after referral significantly decreased [5(IQR 3–6) to 1(IQR 0–4); P = 0.006]. To further delineate the pain clinic's effect, analysis was repeated after removing children initiating hydroxyurea/transfusions upon referral. The significant decrease in hospitalizations persisted [5(IQR 3–6) to 1(IQR 0–4; P = 0.022].Conclusions A multidisciplinary pain management model appears to have decreased SCD pain hospitalizations. Results of this retrospective study will need to be tested in a prospective randomized trial. Pediatr Blood Cancer 2011;56:789–793. © 2010 Wiley‐Liss, Inc.
Sex cord stromal tumors of the ovary in children: A clinicopathological report from the Italian TREP project
Authors: Cecchetto Giovanni , Ferrari Andrea , Bernini Gabriella , Alaggio Rita , Collini Paola , Virgone Calogero , Terenziani Monica , Dall'Igna Patrizia , Cozza Raffaele , Conte Massimo , Bisogno Gianni 
Published: December 2010

AbstractBackgroundOvarian sex‐cord stromal tumors (SCST) are rare in childhood and include a variety of neoplasms with different clinical features and biologic behavior. Aim of the analysis was to report the clinical findings and treatment results of a series of patients with SCST of the ovary, registered in a multi‐institutional Italian network on rare tumors in children and adolescent between 2000 and 2009.MethodsData on 23 patients, 5–176 months old, from 13 Centers were reviewed. All patients were grouped on the basis of the results of the first surgical approach, according to the Children Oncology Group staging system. A cisplatin based chemotherapy was recommended in patients with a localized disease, who had undergone an incomplete excision/initial biopsy, and in case of metastatic spread.ResultsA frequent symptom was abdominal pain; 9/23 cases had signs of hormonal secretion and two patients were hospitalized for acute pain following ovarian torsion. Twelve patients had a Juvenile–Granulosa Cell tumor, six a Sertoli–Leydig Cell tumor, three a Fibrothecoma, and two a Sclerosing‐Stromal tumor. Twenty‐one patients maintained the complete remission (follow‐up: 9–91 months), 2 with a ST II Sertoli–Leydig Cell tumor relapsed and one of them died. Immonohistochemical studies could be done in 10 cases.ConclusionsCompleteness of resection and histology were important prognostic factors; in our series the Sertoli–Leydig Cell tumor was the most aggressive variety. Hormonal signs (precocious puberty, telarca, menarche) were common in younger patients and led to an early diagnosis. Cisplatin based chemotherapy seemed to be effective for locally advanced tumors. Pediatr Blood Cancer 2011;56:1062–1067. © 2010 Wiley‐Liss, Inc.
Targeted large‐scale analysis of protein acetylation
Authors: Mischerikow Nikolai , Heck Albert J. R. 
Published: December 2010

AbstractProtein modifications are biologically important events that may be studied by mass spectrometry‐based high‐throughput proteome analyses. In recent years, several new technologies have emerged that have widened and deepened the targeted analysis of one important, albeit functionally ill‐defined modification, namely protein acetylation. This modification can take place both co‐ and post‐translationally by the transfer of acetyl groups under the catalysis of acetyltransferases. The acetyl group can modify either the α‐amino group at the N‐terminus, so‐called N‐terminal acetylation, or the ε‐amino group on the side chain of lysine residues. Here, we review several emerging targeted technologies to chart both N‐terminal acetylation as well as acetylation at the lysine side chain, on a proteome‐wide scale, highlighting in particular studies that have expanded the biological knowledge on the appearance and function of these common but functionally still less investigated co‐ and post‐translational modifications.
Comprehensive proteomic and transcriptomic characterization of hepatic expression signatures affected in p14 liver conditional knockout mice
Authors: Prokudin Ivan , Stasyk Taras , Rainer Johannes , Bonn Guenther K. , Kofler Reinhard , Huber Lukas A. 
Published: December 2010

AbstractScaffold proteins regulate intracellular MAP kinase signaling by providing critical spatial and temporal specificities. We have shown previously that the scaffold protein MEK1 partner (MP1) is localized to late endosomes by the adaptor protein p14. Using conditional gene disruption of p14 in livers of mice (p14Δhep) we analyzed protein and transcript signatures in tissue samples. Further biological network analysis predicted that the differentially expressed transcripts and proteins are involved in cell cycle progression and regulation of cellular proliferation. Although some of the here identified signatures were previously linked to phospho‐ERK activity, most of them were novel targets of the late endosomal p14/MP1/MEK/ERK signaling module. Finally, the proliferation defect was confirmed in a chemically induced liver regeneration model in p14Δhep knockout mice.
Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines
Authors: Skalnikova Helena , Motlik Jan , Gadher Suresh Jivan , Kovarova Hana 
Published: December 2010

AbstractWithin a mammalian organism, the interaction among cells both at short and long distances is mediated by soluble factors released by cells into the extracellular environment. The secreted proteins may involve extracellular matrix proteins, proteinases, growth factors, protein hormones, immunoregulatory cytokines, chemokines or other bioactive molecules that have a direct impact on target cell phenotype. Stem cells of mesenchymal, adipose, neural and embryonic origin, fibroblast feeder cells as well as primary isolates of astrocytes, endothelial and muscle cells have recently become targets of intensive secretome profiling with the search for proteins regulating cell survival, proliferation, differentiation or inflammatory response. Recent advances and challenges of the stem cell and primary cell secretome analysis together with the most relevant results are discussed in this review.
Proteomics of human embryonic stem cells
Authors: Hughes Chris S. , Nuhn Amelia A. , Postovit Lynne M. , Lajoie Gilles A. 
Published: December 2010

AbstractHuman embryonic stem cells (hESCs) offer exciting potential in regenerative medicine for the treatment of a host of diseases including cancer, Alzheimer's and Parkinson's disease. They also provide insight into human development and disease and can be used as models for drug discovery and toxicity analyses. The key properties of hESCs that make them so promising for medical use are that they have the ability to self‐renew indefinitely in culture and they are pluripotent, which means that they can differentiate into any of more than 200 human cell types. Since proteins are the effectors of cellular processes, it is important to investigate hESC expression at the protein level as well as at the transcript level. In addition, post‐translational modifications, such as phosphorylation, may influence the activity of pivotal proteins in hESCs, and this information can only be determined by studying the proteome. In this review, we summarize the results obtained from several proteomics analyses of hESCs that have been reported in the last few years.
Energy matters: Mitochondrial proteomics for biomedicine
Authors: Gianazza Elisabetta , Eberini Ivano , Sensi Cristina , Barile Maria , Vergani Lodovica , Vanoni Maria Antonietta 
Published: December 2010

AbstractThis review compiles results of medical relevance from mitochondrial proteomics, grouped either according to the type of disease – genetic or degenerative – or to the involved mechanism – oxidative stress or apoptosis. The findings are commented in the light of our current understanding of uniformity/variability in cell responses to different stimuli. Specificities in the conceptual and technical approaches to human mitochondrial proteomics are also outlined.
Proteomics insights into plant signaling and development
Authors: Kaufmann Kerstin , Smaczniak Cezary , de Vries Sacco , Angenent Gerco C. , Karlova Rumyana 
Published: December 2010

AbstractMass spectrometry‐based proteomics is used to gain insight into the abundance and subcellular localization of cellular signaling components, the composition of molecular complexes and the regulation of signaling pathways. Multicellular organisms have evolved signaling networks and fast responses to stimuli that can be discovered and monitored by the use of advanced proteomics techniques in combination with traditional functional analysis. Plants are multicellular organisms and products of tightly regulated developmental programmes that respond to environmental conditions and internal cues. Plant development is orchestrated by inter‐ and intracellular signaling molecules, receptors and transcriptional regulators, which act in a temporal and spatially coordinated manner. Here we review recent advances in proteomics applications used to understand complex cellular signaling processes in plants.
Glycan analysis by modern instrumental methods
Authors: Pabst Martin , Altmann Friedrich 
Published: December 2010

AbstractThe oligosaccharides attached to proteins or lipids are among the most challenging analytical tasks due to their complexity and variety. Knowing the genes and enzymes responsible for their biosynthesis, a large but not unlimited number of different structures and isomers of such glycans can be imagined. Understanding of the biological role of structural variations requires the ability to unambiguously determine the identity and quantity of all glycan species. Here, we examine, which analytical strategies – with a certain high‐throughput potential – may come near this ideal. After an expose of the relevant techniques, we try to depict how analytical raw data are translated into structural assignments using retention times, mass and fragment spectra. A method's ability to discriminate between the many conceivable isomeric structures together with the time, effort and sample amount needed for that purpose is suggested as a criterion for the comparative assessment of approaches and their evolutionary stages.
Indacaterol: a long‐acting beta2‐ agonist taken once daily
Authors: Chaplin Steve , Roberts Michael 
Published: December 2010

AbstractIndacaterol (Onbrez) is a new long‐acting beta2‐agonist taken once daily for the treatment of COPD. In our New products review, Steve Chaplin presents the clinical data relating to its efficacy and adverse effects, and Professor Michael Roberts assesses its place in therapy compared with current treatments. Copyright © 2010 Wiley Interface Ltd