bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTASI TEKNIK BERMAIN PADA PROGRAM KAMPUS MENGAJAR ANGKATAN 6 DALAM MENINGKATKAN KEMAMPUAN LITERASI DAN NUMERASI SISWA SD NEGERI 3 MAYONGLOR
Authors: Diner Lispridona , Indriyani Eka , Akhiroh Elok Nur , Nafi’ah Fiki Zakiyatun , Sari Shelly Novita , Firdaus Zuhairina 
Published: May 2024

Education in Indonesia, especially at the elementary level, still faces big challenges, especially in terms of literacy and numeracy. This difficulty is more pronounced in remote areas, such as what happened at SD Negeri 3 MayongLor, Jepara. Therefore, the Ministry of Education and Culture (Kemendikbud) launched the Class 6 Teaching Campus Program to improve the literacy and numeracy skills of students in these schools. The aim of this research is to determine the effectiveness of implementing playing techniques, with a focus on improving students' literacy and numeracy skills and knowing the advantages and disadvantages of playing techniques in the Class 6 Teaching Campus program at SD Negeri 3 MayongLor. The research method used was quantitative and qualitative, involving 30 students as research subjects. Data was collected through observations, questionnaires, tests and documentation during the three months of program implementation. The results of the questionnaire show that 60% of students strongly agree that learning literacy and numeracy is fun, 66% of students strongly agree and agree that they are motivated to learn literacy and numeracy through playing techniques, 53% of students strongly agree and agree that they can master literacy and numeracy effectively and 51% Students strongly agree that they can master literacy and numeracy through digital-based play techniques. It can be concluded that there is effectiveness in improving literacy and numeracy learning outcomes through techniques in the Class 6 Teaching Campus Program at SD Negeri 3 MayongLor.
Hubungan Antara Trombositpoenia Dengan IgM, IgG Pada Pasien Demam Berdarah Dengue di Puskesmas Polowijen
Authors: Rodolof Claudya Putri , Mahtuti Erni Yohani , Rahmawati Previta Zeizar 
Published: May 2024

Dengue hemorrhagic fever (DHF) caused by the dengue virus with general symptoms of fever, joint pain, rash and thrombocytopenia. One of the tests of the immune system in DHF is IgM and IgG. The purpose o determine the relationship between thrombocytopenia and (IgM) and (IgG) in patients with dengue hemorrhagic fever at the Polowijen Health Center in Malang City. The method is in the form of laboratory descriptive observational, carried out from May to June 2023. sampling by Accidental Sampling with a total of 25 patients. The results of the study of 25 patients with dengue hemorrhagic fever, 13 female patients (52%) and 12 male patients (48%). Based on the age category, there were 4 patients with dengue hemorrhagic fever under five (16%), children 10 patients (40%), adolescents 4 patients (16%) and early adults 7 patients (28%). The results of the infection category included primary 8 patients (32%), secondary infection 17 (68%). The results of data analysis with Pearson correlation showed a relationship between thrombocytopenia and IgM p = 0.029 r = 0.436 meaning that there is a strong and unidirectional relationship between thrombocytopenia and IgM. Thrombocytopenia with IgG p = 0.056 r = 0.387 means that there is a strong and unidirectional relationship between thrombocytopenia and IgG. The relationship between IgM and IgG is p = 0.093 r = -0.343. Which means that between IgM and IgG there is a strong inverse relationship, that is, if IgM is positive then IgG is negative, and vice versa
Pengetahuan Tentang Keputihan Berhubungan Dengan Pelaksanaan Kebersihan Genitalia Siswi di MAN 1 Kota Malang
Authors: Sila Maria Azerina D Timo , Susmini Susmini , Ka'arayeno Arie Jefry 
Published: May 2024

Kebersihan di area vulva sering tidak diperhatikan secara khusus oleh kaum hawa, padahal jika dibiarkan secara terus menerus berdampak pada kesehatan dan rentan terinfeksi virus berbahaya. Kurangnya pemahaman ditambah rendahnya pelaksanaan melakukan kebersihan daerah genital menjadi masalah dalam penelitian ini. Tujuan penelitian mengetahui hubungan pengetahuan keputihan dengan pelaksanaan melakukan kebersihan genitalia siswi di MAN 1 Kota Malang. Desain yang digunakan adalah cross sectional. Populasi yakni semua siswi yang belajar di MAN 1 Kota Malang yang berjumlah 400 siswi, dengan teknik accidental sampling diperoleh sampel 120 orang. Data diambil dengan lembar kuesioner, dan uji analisa data chi square. Dari hasil didapatkan lebih dari separuh responden (74.2%) memiliki pengetahuan tentang keputihan kategori cukup, sebagian besar responden (85.0%) memiliki perilaku vulva hygiene kategori kurang; terdapat hubungan yang signifikan pengetahuan siswi tentang keputihan dengan pelaksanaan kebersihan genital siswi di MAN 1 Kota Malang (p value 0,050) Peneliti selanjutnya diharapkan dapat melihat hubungan faktor eksternal seperti kebersihan lingkungan dan dapat memberikan penyuluhan tentang cara melakukan vulva hygiene bagi remaja di sekolah.
Acesso ao tratamento odontológico no SUS: Revisão sistemática e metánalise
Authors: Rafael Luiza Guimarães , Moreira Gabriele Lopes , Colodette Renata Maria 
Published: May 2024

Objetivo. Analisar, por meio de uma revisão sistemática, a prevalência do acesso aos serviços odontológicos nas Unidades Básicas de Saúde brasileiras. Métodos: Foi realizada uma revisão sistemática e uma metánalise. Selecionou-se estudos publicados entre janeiro de 2002 e setembro de 2023 nas bases de dados Literatura Latino-America¬na e do Caribe em Ciências da Saúde (LILACS), MEDLINE (via PubMed), Scientific Electronic Library Online (SciELO) e Scopus. A estratégia de busca foi prevalência E acesso aos serviços de saúde E serviços de saúde bucal E brasil. (DeCS e Palavras) ou prevalence AND health services accessibility AND dental health services AND brazil. O desfecho primário foi a prevalência de acesso aos serviços de Saúde Bucal na APS com seu respectivo Intervalo de Confiança de 95%. Foi utilizado o teste qui-quadrado (χ2), com uma significância de (p < 0,10) para avaliar a heterogeneidade. Resultados. A prevalência agrupada de acesso aos serviços de saúde bucal entre indivíduos investigados foi de 34% (IC95%: 0,17 - 0,51). A heterogeneidade entre os estudos foi substancial, demostrada pelo teste Q (p < 0,001) e pela estatística I2 (I2 = 99,94%). Conclusão: O presente estudo demonstra uma prevalência de 34% de acesso aos serviços odontológicos e fatores como renda, dieta, nível de escolaridade e disponibilidade do serviço, estão fortemente ligados a obtenção de tratamentos odontológicos, tendo um impacto direto na qualidade de vida das pessoas.
Cuidados e desafios vivenciados pelos pais na Unidade de Terapia Intensiva Neonatal: Revisão integrativa
Authors: Silva Maria Luiza Borburema da , Lopes Thais Rosental Gabriel , Sales José Renato Paulino de , Silva Jéssica Aslan Santos da , Dantas Lívia de Azevedo , Carvalho Jovanka Bittencourt Leite de 
Published: May 2024

Objetivo: caracterizar quais os cuidados e desafios vivenciados pelos pais ao lidar com seu filho internado na UTIN, realizando o Método Canguru, em sua primeira etapa. Método: trata-se de uma revisão integrativa com buscas realizadas nas bases de dados: Medical Literature Analysis and Retrieval System Online (MEDLINE), Science Direct, SCOPUS e Web of Science. Após critérios de elegibilidade, a amostra final foi constituída por 34 artigos, resultando em oito temas principais. Resultados: os temas encontrados foram: Sentimentos antagônicos; Aleitamento materno; Ambiente da Unidade de Terapia Intensiva Neonatal; Relação com a equipe de saúde e participação no cuidado; Método Canguru; Redes de apoio; Papel materno x Papel paterno. Conclusão: percebeu-se a diversidade na abordagem sobre as vivências dos pais na Unidade de Terapia Intensiva Neonatal. Houve unanimidade sobre a importância da vinculação precoce entre pais e filhos, necessitando de maior sensibilidade dos profissionais de saúde na inserção precoce entre ambos. Contribuições para a prática: a partir dos resultados foi possível a elaboração e validação do guia prático com vistas à auxiliar os pais durante a internação na Unidade de Terapia Intensiva Neonatal.
Faktor Yang Berhubungan dengan Tingkat Pengetahuan Perawat Dalam Ketepatan Identifikasi Insiden Keselamatan Pasien di Rumah Sakit RSUD Dr. H. Moch. Ansari Saleh Banjarmasin
Authors: Jailani Muhamad , Wijaksono Muhammad Arief , Basit Mohammad 
Published: May 2024

Faktor seorang perawat sangat berpengaruh terhadap pengetahuan perawat, semakin tinggi faktor internal yang dimiliki maka semakin beragam pengetahuannya, karena perawat dituntut menjalankan profesi berdasarkan pendidikan yang baik dan sikap yang dapat meningkatkan pengetahuan, produktifitas perawat, dan dapat menjadi dasar dalam pengembangan diri seorang perawat dalam melakukan identifikasi insiden keselamatan pasien di rumah sakit. Agar dapat mengetahui hubungan faktor internal mempengaruhi pengetahuan perawat tentang ketepatan identifikasi insiden keselamatan pasien di rumah sakit. Metode penelitian ini menggunakan kuantitatif dengan metode deskriptif, populasi perawat sebanyak 40 orang dengan teknik pengambilan sampel purposive sampling. Instrumen penelitian menggunakan kuisioner. Analisis data menggunakan analisis deskriptif. Hasil penelitian didapatkan faktor internal paling banyak menjawab baik sebanyak 65.5%, jawaban cukup sebanyak 52.5% dan jawaban kurang sebanyak 0%. Sikap menjawab baik (65.0%), cukup (35.0%) dan kurang (0%). Tingkat pengetahuan menjawab kurang 57.5%, cukup 35.0% dan baik 7.5%. Hasil uji statistik Spearman Rank diketahui nilai r=0,.532>0,51 yang artinya Hubungan kuat pada penelitian bahwa terdapat hubungan antara faktor internal dan tingkat pengetahuan di rsud ansari Banjarmasin. Ada hubungan antara faktor internal dan tingkat pengetahuan perawat dalam identifikasi insiden keselamatan pasien RSUD Dr. H. Moch. Ansari Saleh Banjarmasin.
Pengaruh penambahan mangan alam terhadap daya absorbsi cahaya tampak pada keramik TiO2
Authors: Elfianti. A Warda , Agusu La , Eso Rosliana 
Published: May 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penambahan mangan alam terhadap daya absorbsi cahaya yang tampak pada keramik Ti. Mangan ditambahkan kedalam Ti dengan perbandingan yang diberikan yaitu (0% : 100% untuk sampel A ), (1% : 99% untuk sampel B), (3% : 97% untuk sampel C), (5% : 95% untuk sampel D). Penelitian ini diawali dengan menganalisa kadar mangan menggunakan uji AAS, hasil analisis kadar mangan alam diperoleh mangan dengan kemurnian 44,77 %. Karakterisasi yang digunakan adalah Spektofotometer Uv-Vis. Hasil analisis menunjukan pada TiO2 murni tidak memiliki puncak serapan sedangkan untuk TiO2 yang telah ditambahkan mangan alam memiliki dua puncak serapan yaitu pada rentang panjang gelombang 220 nm dan 350 nm. Puncak serapan tertinggi pada 97 % TiO2 dopping 3% mangan yaitu sebesar 23,8%. Pita serapan bergeser ke arah kanan ke panjang gelombang lebih tinggi sehingga energinya lebih kecil. Energi band gap TiO2 pada indirect band gap sebesar 3,97 eV dan Direct band gap sebesar 1,96 eV. Penambahan konsentrasi dopping mangan alam sebesar 1%, 3% dan 5% diperoleh nilai untuk indirect band gap masing-masing sebesar 3,94 eV, 3,25 eV dan 3,19 eV sedangkan untuk direct band gap masing-masing sebesar 1,20 eV, 1,33 eV dan 1,34 eV
Assessing vulnerability and enhancing resilience of port systems in southeast Texas facing sea-level rise
Authors: Amer Reda 
Published: May 2024

Climate change and the associated sea level rise (SLR) are presenting newfound challenges to the port systems and coastal transportation infrastructure of southeast Texas. This paper introduces a Geographic Information Systems (GIS) based model designed to simulate inundation scenarios under various sea-level projections, aiming to assess the vulnerabilities of both port facilities and road networks. The study area encompasses a specific region within Jefferson County, southeast Texas, encompassing three major ports: Port Arthur, Beaumont, and Orange. Utilizing a high-resolution (1-m) Digital Elevation Model (DEM) derived from the 2017 LiDAR dataset, this model is integrated with NASA’s sea-level rise projections to compute the extent and volume of inundation across low, medium, and high SLR scenarios. Drawing from monthly mean sea level data spanning from 1958 to 2020, the lowest SLR projections, derived from the relative sea-level trend measured at the Sabine Pass, TX gauge station, indicate a yearly increase of 6.16 mm, with a 95% confidence interval of +/- 0.74 mm. Projections for 2050 and 2,100 show the lowest SLR at 0.17 m and 0.48 m, respectively. In contrast, the medium to high RSLR projections under the IPCC SSP3-7.0 scenario for 2050 and 2,100 stand at 0.54 m and 1.34 m, respectively. The findings reveal that, under medium to high SLR scenarios, the extent of inundated areas in the study region is expected to expand by 12.4% in 2050 and 19.9% in 2,100, compared to the lowest SLR projection. Additionally, the length of submerged roadways is predicted to increase by 6.9% in 2050 and 13.3% in 2,100, in comparison to the lowest SLR projection. It is worth noting that some margin of error may be introduced due to factors such as the width of the port area and access roads, the high-resolution DEM, and the alignment of computed inundated areas with the existing topography. Overall, the manuscript highlights the urgency of proactive planning and underscores the importance of safeguarding critical infrastructure in the context of climate change and SLR.
Six factors facilitating teachers’ use of research. An experimental factorial survey of educational stakeholders perspectives
Authors: Jeune Nathanael , Juhel Jacques , Dessus Philippe , Atal Ignacio 
Published: May 2024

IntroductionTeachers’ use of research has been increasingly advocated for in the past few decades, and some research has documented the factors which positively or negatively influence teachers’ use of research. However, the existing research does not give relevant information to prioritize between different ways to facilitate teachers’ use of research. In addition, different professionals working in education may have divergent opinions about such priorities. This study therefore asks what are the factors that most influence teachers’ use of research according to teachers, teacher trainers, educational decision makers and researchers?MethodsWe conducted a factorial survey experiment on six factors with 100 participants (pilot study) and 340 participants (main study) to identify which factors were perceived as influencing the most teachers’ use of research and to compare respondents’ perceptions according to their main role in education.ResultsThis study shows that support for research use by the institution and instrumental utility of research are the factors that were judged as most impactful. Some categories of respondents had conflicting views about specific factors, for instance researchers perceiving teachers’ involvement in research as less likely to facilitate teachers’ use of research.ConclusionThese findings can help decision-makers and teacher-trainers with limited resources to allocate them in a more effective way, while taking into consideration the disagreements across professions in order to resolve possibly arising conflicts.
Ketogenic diet enhances the anti-cancer effects of PD-L1 blockade in renal cell carcinoma
Authors: Richard Jeremy , Beauvillain Céline , Benoit Maxime , Barth Magalie , Aubert Cécile , Rolley Cyrielle , Bellal Sarah , Bourreau Jennifer , Ferragu Matthieu , Lebdai Souhil , Chevrollier Arnaud , Henrion Daniel , Procaccio Vincent , Bigot Pierre 
Published: May 2024

IntroductionClear cell renal cell carcinoma (ccRCC) is characterized by a predominant metabolic reprogramming triggering energy production by anaerobic glycolysis at the expense of oxydative phosphorylation. Ketogenic diet (KD), which consists of high fat and low carbohydrate intake, could bring required energy substrates to healthy cells while depriving tumor cells of glucose. Our objective was to evaluate the effect of KD on renal cancer cell tumor metabolism and growth proliferation.MethodsGrowth cell proliferation and mitochondrial metabolism of ACHN and Renca renal carcinoma cells were evaluated under ketone bodies (KB) exposure. In vivo studies were performed with mice (nude or Balb/c) receiving a xenograft of ACHN cells or Renca cells, respectively, and were then split into 2 feeding groups, fed either with standard diet or a 2:1 KD ad libitum. To test the effect of KD associated to immunotherapy, Balb/c mice were treated with anti-PDL1 mAb. Tumor growth was monitored.ResultsIn vitro, KB exposure was associated with a significant reduction of ACHN and Renca cell proliferation and viability, while increasing mitochondrial metabolism. In mice, KD was associated with tumor growth reduction and PDL-1 gene expression up-regulation. In Balb/c mice adjuvant KD was associated to a better response to anti-PDL-1 mAb treatment.ConclusionKB reduced the renal tumor cell growth proliferation and improved mitochondrial respiration and biogenesis. KD also slowed down tumor growth of ACHN and Renca in vivo. We observed that PDL-1 was significantly overexpressed in tumor in mice under KD. Response to anti-PDL-1 mAb was improved in mice under KD. Further studies are needed to confirm the therapeutic benefit of adjuvant KD combined with immunotherapy in patients with kidney cancer.
Effects of long and short ejaculatory abstinence on sperm parameters: a meta-analysis of randomized-controlled trials
Authors: Lo Giudice Arturo , Asmundo Maria Giovanna , Cimino Sebastiano , Cocci Andrea , Falcone Marco , Capece Marco , Abdelhameed Ali Saber , Capogrosso Paolo , Morgado Afonso , Tsampoukas Georgios , Manfredi Celeste , Russo Giorgio Ivan 
Published: May 2024

PurposeThis study aimed to investigate the effects of ejaculatory abstinence on sperm parameters.MethodsThis analysis was registered in PROSPERO (CRD42023472124). We performed a search on PubMed using the following text terms: ((“sperm parameters” OR “sperm analysis” [Mesh]) AND (“sperm DNA fragmentation” OR “DNA fragmentation” [Mesh]) AND (“sexual abstinence” [Mesh] OR “abstinence”)) and an advanced search in Scopus using the terms (“sperm parameters” OR “sperm parameters” OR “DNA fragmentation”) AND (“abstinence”). The sperm parameters that were investigated were sperm volume, total sperm motility, progressive sperm motility, sperm concentration, sperm morphology, and sperm DNA fragmentation (SDF). A two-day cut-off as a “short” or “long” abstinence period has been defined.ResultsThirteen studies published between 2013 and 2022 were included in this meta-analysis. A total of 2,315 patients, ranging from 6 to 836 from each cohort, were enrolled in the study. We showed that longer abstinence time was associated with greater sperm concentration (mean difference [MD]: 8.19; p &lt;0.01), sperm volume (MD: 0.96; p &lt;0.01), and higher SDF (MD: 3.46; p &lt;0.01), but lower progressive sperm motility (MD: −1.83; p &lt;0.01). Otherwise, no statistically significant difference was observed in patients with longer vs. shorter abstinence times regarding total sperm motility (MD: −1.83; p = 0.06). Meta-regression analysis showed that days of abstinence were positively and linearly related to sperm concentration (slope: 3.74; p &lt;0.01) and SDF (slope: 0.65; p = 0.044).ConclusionsAccording to our data, short ejaculatory abstinence is associated with better sperm quality. Indeed, a higher percentage of progressive sperm motility and lower levels of SDF have been reported in a short abstinence cohort. In contrast, the long abstinence group reported a higher sperm concentration.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023472124.
Identification of cytokines in benign and malignant thymus tumors: based on Mendelian randomization and proteomics
Authors: Zhu Kangle , Shi Jingwei , Yang Rusong , Zhou Chu , Liu Zhengcheng 
Published: May 2024

ObjectiveThe aim of this study was to identify potential causal cytokines in thymic malignancies and benign tumors from the FinnGen database using Mendelian randomization (MR).MethodsIn this study, data from genome-wide association studies (GWAS) of 91 cytokines were used as exposure factors, and those of thymic malignant tumors and thymic benign tumors were the outcome variables. Two methods were used to determine the causal relationship between exposure factors and outcome variables: inverse variance weighting (IVW) and MR-Egger regression. Sensitivity analysis was performed using three methods, namely, the heterogeneity test, the pleiotropy test, and the leave-one-out test.ResultsThere was a causal relationship between the expression of fibroblast growth factor 5, which is a risk factor for thymic malignant tumors, and thymic malignant tumors. C-C motif chemokine 19 expression, T-cell surface glycoprotein CD5 levels, and interleukin-12 subunit beta levels were causally related to thymic malignant tumors and were protective. Adenosine deaminase levels, interleukin-10 receptor subunit beta expression, tumor necrosis factor (TNF)-related apoptosis-inducing ligand levels, and TNF-related activation-induced cytokine levels showed a causal relationship with thymic benign tumors, which are its risk factors. Caspase 8 levels, C-C motif chemokine 28 levels, interleukin-12 subunit beta levels, latency-associated peptide transforming growth factor beta 1 levels, and programmed cell death 1 ligand 1 expression showed a causal relationship with thymic benign tumors, which are protective factors. Sensitivity analysis showed no heterogeneity.ConclusionCytokines showed a causal relationship with benign and malignant thymic tumors. Interleukin-12 subunit beta is a common cytokine that affects malignant and benign thymic tumors.