bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes of Operated Cases of Central Nervous System Metastases at a Tertiary Cancer Hospital – An Analysis
Authors: Sundar I. Vijay 
Published: April 2024

Abstract

Background:
Recent advances in the treatment have increased the survival of patients with common cancers. As a result, the incidence of symptomatic central nervous system (CNS) metastases has increased over time. Although systemic therapies remain the mainstay of metastatic cancers, surgical treatment is often required for progressive neurological deficits and to buy time for other modalities to be effective. The present retrospective study aimed to analyze various demographic, neurological, and short-term survival outcomes among operated cases of symptomatic CNS metastases.

Materials and Methods:
All surgically treated symptomatic brain and spine metastasis patients between August 2018 and March 2022 were included in the study. Patients who underwent procedures for primary tumors of the brain and spine were excluded. The details of demographic and clinical profile, neurological data, surgical treatment, and short-term survival data were retrieved from hospital medical records and analyzed. Patients with motor deficits (power grade 3/5 or less) were analyzed to look for improvement in motor deficits after surgery.

Results:
The first 100 operated cases of symptomatic CNS metastases were reviewed. The mean age of presentation was 46.42 years (females – 44.28, males – 49.13). Breast malignancy was the most common source of primary overall (29%) and lung malignancy (15%) was second most common. A total of 53 brain surgeries and 47 spine surgeries were performed. Preoperative motor deficits were seen more commonly among spine metastases (30/47) than brain metastases (17/53) patients. Around 64% of patients who presented with neurological deficits (motor deficits) had improvement postsurgery. Such improvement from deficits was observed more in patients with spine metastases (23/30; 76.7%) than brain metastases (7/17; 41.2%).

Conclusion:
Neurosurgery has an important role in the management of CNS metastases, and timely surgical intervention in a selected group of symptomatic CNS metastases can improve the quality of life of the patients.
Towards efficient and reliable utilization of automated data collection: Media scrapers applied to news on climate change
Authors: Mervaala Erkki , Lyytimäki Jari 
Published: April 2024

Abstract: Automated data collection provides tempting opportunities for social sciences and humanities studies. Abundant data accumulating in various digital archives allows more comprehensive, timely and cost-efficient ways of harvesting and processing information. While easing or even removing some of the key problems, such as laborious and time-consuming data collection and potential errors and biases related to subjective coding of materials and distortions caused by focus on small samples, automated methods also bring in new risks such as poor understanding of contexts of the data or non-recognition of underlying systematic errors or missing information. Results from testing different methods to collect data describing newspaper coverage of climate change in Finland emphasize that fully relying on automatable tools such as media scrapers has its limitations and can provide comprehensive but incomplete document acquisition for research. Many of these limitations can, however, be addressed and not all of them rely on manual control.
АНТИНОМИЧЕСКАЯ ПАРА «МЕСТЬ» И «ПРОЩЕНИЕ» В ПОВЕСТИ-СКАЗКЕ Л. БОРОДИНА «ГОД ЧУДА И ПЕЧАЛИ»
Authors: Родина Ирина 
Published: April 2024

В статье рассматривается тема милосердия на материале сказки-повести «Год чуда и печали» как ключевая тема творчества Л.Бородина, освещаются аксиологические доминанты христианского мироощущения в аспекте таких категорий как как добро и зло, преступление и наказание, любовь и ненависть, милосердие и сострадание, чудо.
TIBBIY TA’LIM TALABALARIDA MEDIAKOMPETENTLIKNI RIVOJLANTIRISH METОDIKАSI
Authors: Muydinov Firuzjon 
Published: April 2024

Tibbiy ta’lim talabalarini mediаkompetentligini rivojlantirishga yо‘nаltirilgаn pedаgоgik jаrаyоndа qо‘lgа kiritilgаn nаtijаlаrni tаhlil qilish vа umumlаshtirish, sаmаrаdоrlik dаrаjаsini аniqlаsh metоdikаsini ishlаb сhiqish muhim аhаmiyаtgа egа. Bu оrqаli mаzkur muаmmоning аhаmiyаti, uni yeсhishning pedаgоgik mоdeli, shаrt-shаrоitlаri vа u оrqаli erishilаdigаn nаtijаlаrni kо‘rish mumkin bо‘lаdi. Shuningdek, tibbiy tа’lim tizimi uсhun mediakompetentlikni rivojlantirishning zаrurаti vа bо‘lаjаk shifokorlarni tаrbiyаlаshdаgi muhimligini kо‘rsаtib berish оrqаli tаdqiqоt ishining ilmiy fаrаzini isbоtlаsh mumkin bо‘lаdi. Shungа kо‘rа, bо‘lаjаk shifokorlarning medikompetentligini rivojlantirishgа yо‘nаltirilgаn pedаgоgik tizim sаmаrаdоrligini аniqlаshning muhim shаrtlаridаn biri – tа’kidlоvсhi tаjribа-sinоv ishlаrining tо‘g‘ri tаshkil etilishidir. Tаsdiqlоvсhi tаjribа-sinоv ishlаri оrqаli tаjribа ishlаrining mаqsаdi vа vаzifаlаri, eksperimentning аniq mezоnlаri, shаrt-shаrоitlаrining nаzаriy tаhlili keltirilаdi vа bu оrqаli tаsdiqlоvсhi tаjribа ishlаrining mаzmunini аnglаsh mumkin bо‘lаdi.
ДАВЛАТ ХИЗМАТЧИЛАРИДА БОШҚАРУВ КОМПЕТЕНЦИЯЛАРИНИ ШАКЛЛАНТИРИШ БОРАСИДА ХОРИЖ ТАЖРИБАСИ
Authors: Саидов Сарвар 
Published: April 2024

Мазкур мақолада мамлакатимизда давлат фуқаролик хизмати институтини янада такомиллаштириш, давлат хизматчиларининг бошқарув ва касбий компетенцияларини ривожлантириш бўйича илғор хориж тажрибасининг ўзига хос хусусиятлари тадқиқ қилинган. Осиё ва Европанинг етакчи мамлакатларида давлат хизматчиларини тайёрлаш тизими тамойиллари ва асосий тенденциялари кўриб чиқилган. Шунингдек, Туркия, Япония, Жанубий Корея каби ривожланган мамлакатларда давлат хизматчиларини тайёрлашнинг устувор йўналишлари ва уларга қўйилган талаблар аниқланган.
ИНГЛИЗ ВА ЎЗБЕК АНТРОПОНИМИК ЛУҒАТЛАР ТИПОЛОГИЯСИ
Authors: Жўраева Ирода 
Published: April 2024

Мақолада инглиз ва ўзбек антропонимик луғатларининг типологияси ҳақида фикр юритилади. Унда инглиз ва ўзбек тилларидаги антропонимик луғатларнинг турлари: босма ва онлайн антропонимик луғатлар ва уларнинг турлари, тузилиши, мазмуни, ҳажми ҳақида, шунингдек, бир тилли ва икки тилли луғатлар, маълумотларни жойлаштириш услубига кўра, даврийлиги, ҳажмига кўра, жинс турига кўра, ижтимоий мавқе, ёшига кўра турлари таҳлил қилинган.
Konsep Modern Classic Pada Perancangan Interior Novela Galery
Authors: Hasna Hanan 
Published: April 2024

Novela gallery merupakan sebuah tempat persewaan kebaya, make up dan juga hairdo yang tempat usahanya berada di dalam sebuah rumah tinggal. Dikarenakan tempat tersebut sudah tidak dijadikan lagi sebagai rumah tinggal menjadi sebuah alasan untuk mengubah Novela Galery agar dapat dikembangkan lagi menjadi usaha yang bisa mendapat lebih banyak klien. Tujuan penulisan Artikel ini adalah a) Mendesain Novela Galery dengan konsep Modern Classic b) Menciptakan tata layout yang sesuai dengan fungsi Novela Galery c) Menerapkan material yang sesuai dengan konsep Modern Classic. Dalam melakukan penelitian, dilakukakan beberapa metode pencarian data melalui observasi dengan studi literatur, wawancara dan dokumentasi. Dari hasil metode pencarian tersebut bahwa konsep Modern Classic cocok diterapkan untuk Novela Galery. Konsep Modern Classic diaplikasian baik itu dalam pemilihan bentuk, dinding, lantai, ceiling, tata letak, furniture, dekorasi dan juga pemilihan material.
Regulasi Emosi Pada Mahasiswa Yang Mengalami Hubungan Toxic Relationship
Authors: Agustin Mellani , Dewi Rantri Mustika 
Published: April 2024

Regulasi emosi berarti suatu kemampuan yang dimiliki oleh individu untuk menilai, mengatasi, mengelola, dan mengungkapkan emosi yang tepat untuk mencapai keseimbangan emosional , Penelitian ini bertujuan untuk mengetahui regulasi emosi pada mahasiswa yang mengalami hubungan toxic relantionship. Metode penelitian ini menggunakan penelitian kualitatif dengan pendekatan fenomenologi. Partisipan berjumlah tujuh orang, terdiri dari tiga partisipan laki laki dan empat partisipan perempuan. Teknik pengumpulan data wawancara. Hasil analisis menemukan bahwa setiap individu memiliki sumber emosi yang berbeda-beda saat menjalani hubungan toxic relantionship. Perbedaan sumber emosi juga mengarahkan pada strategi khusus untuk regulasi emosi, serta hal apa saja yang mempengaruhi kondisi emosi individu dan regulasi emosinya.
Summertime tropospheric ozone source apportionment study in the Madrid region (Spain)
Authors: de la Paz David , Borge Rafael , de Andrés Juan Manuel , Tovar Luis , Sarwar Golam , Napelenok Sergey L. 
Published: April 2024

Abstract. The design of emission abatement measures to effectively reduce high ground-level ozone (O3) concentrations in urban areas is very complex. In addition to the strongly non-linear chemistry of this secondary pollutant, precursors can be released by a variety of sources in different regions, and locally produced O3 is mixed with that transported from the regional or continental scales. All of these processes depend also on the specific meteorological conditions and topography of the study area. Consequently, high-resolution comprehensive modeling tools are needed to understand the drivers of photochemical pollution and to assess the potential of local strategies to reduce adverse impacts from high tropospheric O3 levels. In this study, we apply the Integrated Source Apportionment Method (ISAM) implemented in the Community Multiscale Air Quality (CMAQ v5.3.2) model to investigate the origin of summertime O3 in the Madrid region (Spain). Consistent with previous studies, our results confirm that O3 levels are dominated by non-local contributions, representing around 70 % of mean values across the region. Nonetheless, precursors emitted by local sources, mainly road traffic, play a more important role during O3 peaks, with contributions as high as 25 ppb. The potential impact of local measures is higher under unfavorable meteorological conditions associated with regional accumulation patterns. These findings suggest that this modeling system may be used in the future to simulate the potential outcomes of specific emission abatement measures to prevent high-O3 episodes in the Madrid metropolitan area.
Bergen metrics: composite error metrics for assessing performance of climate models using EURO-CORDEX simulations
Authors: Samantaray Alok K. , Mooney Priscilla A. , Vivacqua Carla A. 
Published: April 2024

Abstract. Error metrics are useful for evaluating model performance and have been used extensively in climate change studies. Despite the abundance of error metrics in the literature, most studies use only one or two metrics. Since each metric evaluates a specific aspect of the relationship between the reference data and model data, restricting the comparison to just one or two metrics limits the range of insights derived from the analysis. This study proposes a new framework and composite error metrics called Bergen metrics to summarize the overall performance of climate models and to ease interpretation of results from multiple error metrics. The framework of Bergen metrics are based on the p norm, and the first norm is selected to evaluate the climate models. The framework includes the application of a non-parametric clustering technique to multiple error metrics to reduce the number of error metrics with minimum information loss. An example of Bergen metrics is provided through its application to the large ensemble of regional climate simulations available from the EURO-CORDEX initiative. This study calculates 38 different error metrics to assess the performance of 89 regional climate simulations of precipitation and temperature over Europe. The non-parametric clustering technique is applied to these 38 metrics to reduce the number of metrics to be used in Bergen metrics for eight different sub-regions in Europe. These provide useful information about the performance of the error metrics in different regions. Results show it is possible to observe contradictory behaviour among error metrics when examining a single model. Therefore, the study also underscores the significance of employing multiple error metrics depending on the specific use case to achieve a thorough understanding of the model behaviour.
Firn air content changes on Antarctic ice shelves under three future warming scenarios
Authors: Veldhuijsen Sanne B. M. , van de Berg Willem Jan , Kuipers Munneke Peter , van den Broeke Michiel R. 
Published: April 2024

Abstract. The Antarctic firn layer provides pore space in which an estimated 94 % to 96 % of the surface melt refreezes or is retained as liquid water. Future depletion of firn pore space by increased surface melt, densification and formation of low-permeability ice slabs can potentially lead to meltwater ponding, hydrofracturing and ice-shelf disintegration. Here, we investigate the 21st-century evolution of total firn air content (FAC) and accessible FAC (i.e. the pore space that meltwater can reach) across Antarctic ice shelves. We use the semi-empirical IMAU Firn Densification Model (IMAU-FDM) with an updated dynamical densification expression to cope with changing climate forcing. The firn model is forced by general circulation model output of the Community Earth System Model version 2 (CESM2) for three climate emission scenarios (SSP1-2.6, SSP2-4.5 and SSP5-8.5), dynamically downscaled to a 27 km horizontal resolution by the Regional Atmospheric Climate Model version 2.3p2 (RACMO2.3p2). To estimate accessible FAC, we prescribe a relationship between ice-slab thickness and permeability. In our simulations, ice shelves on the Antarctic Peninsula and the Roi Baudouin Ice Shelf in Dronning Maud Land are particularly vulnerable to total FAC depletion (> 50 % decrease by 2100), even for low-emission (SSP1-2.6) and intermediate-emission (SSP2-4.5) scenarios. In the high-emission (SSP5-8.5) scenario in particular, the formation of ice slabs further reduces accessible FAC on ice shelves with low accumulation rates (current rates of < 500 mmw.e.yr-1), including many East Antarctic ice shelves and the Filchner–Ronne, Ross, Pine Island and Larsen C ice shelves. These results underline the potentially large vulnerability of low-accumulation ice shelves to firn air depletion through ice-slab formation.
Post-Separation Parenting Apps in the Context of Family Violence: Harm Minimisation versus Harm Facilitation
Authors: Irving Michelle 
Published: April 2024

Post-separation parenting apps are designed for separated parents to use as a dedicated space for child-related communication and organisation. Their enhanced record-keeping features often lead to recommendations for their use within the context of family law and they are likely to appeal to victim/survivors of family violence. However, concerns have also been raised about their potential misuse by perpetrating parents. Using responses to an online survey about post-separation parenting apps, this study explores the tension between the harms and benefits of app use under these circumstances. Data were examined from 33 mothers who reported experiencing family violence via parenting apps. Comparative methods were used to contrast those who endorsed beneficial outcomes from app use with those whose outcomes were detrimental (net-benefit case group [n = 24] vs net-detriment case group [n = 9], respectively). Overall, mothers in the net-benefit case group reported a shorter time since separation (M = 3 years) and fewer experiences of app misuse by the other parent. For these mothers, apps worked to minimise harmful perpetrator conduct by deterring and/or capturing abusive behaviours and affording containment and boundary setting around interactions. By contrast, those in the net-detriment case group were separated longer (M = 6.9 years) and reported a higher incidence of app misuse and fear. These participants experienced a range of app-facilitated harms centred on perpetrators’ false narratives and manipulation. These results suggests that while post-separation parenting apps may be useful harm-minimisation tools for many victim/survivors of post-separation family violence, they are not a panacea for parenting communication in all such contexts – particularly where there is entrenched coercive control.
“Failing splendidly” and the price of success: Feminist struggle between revolution and reformation
Authors: Huegel Viktoria 
Published: April 2024

With Euripides’s Bacchae Honig, in A Feminist Theory of Refusal (2021), chooses a story that easily can be read as an “errant path”: the story of a group of “honey-mad” women who, driven by a Dionysian force, slaughter their own kin and are eventually put back into place by fatherly reprimand. Against that, Honig retells the story of the women of Cithaeron as what W.E.B. Du Bois called a “splendid failure” - “a possibility first nurtured outside the city is extinguished, but memory remains” (p. 5). In the three moments that I look at in the following, we find an affirmative politics and a politics of celebration that Honig herself follows in her writing: she lays new foundations upon which future democratic struggle can build. The narrative of “failure,” even in the “splendid form” that Honig employs, however, misses an important aspect of the story: namely the violence and forms of domination that held back the city. Honig reproaches Arendt for not being attuned to the archive’s logic of closure that prevents the seeds of the women’s struggle to flourish in the city. But is Honig? Recognizing the conditions that have led to the bacchant’s failure might push us to think about the work of reformation, or rather transformation, as part of a revolutionary feminist struggle.
COVID-19 impact in Crohn’s disease patients submitted to autologous hematopoietic stem cell transplantation
Authors: Ruiz Milton Artur , Kaiser Junior Roberto Luiz , Piron-Ruiz Lilian , Pinho Tainara Souza , Castiglioni Lilian , de Quadros Luiz Gustavo 
Published: April 2024

BACKGROUND
Severe acute respiratory syndrome coronavirus 2 is the virus responsible for coronavirus disease 2019 (COVID-19), a disease that has been blamed for inducing or exacerbating symptoms in patients with autoimmune diseases. Crohn's disease (CD) is an inflammatory bowel disease that affects genetically susceptible patients who develop an abnormal mucosal immune response to the intestinal microbiota. Patients who underwent hematopoietic stem cell transplantation (HSCT) are considered at risk for COVID-19.
AIM
To describe for the first time the impact of COVID-19 in CD patients who had undergone autologous, non-myeloablative HSCT.
METHODS
In this descriptive study a series of 19 patients were diagnosed with positive COVID-19. For two patients there were reports of the occurrence of two infectious episodes. Parameters related to HSCT, such as time elapsed since the procedure, vaccination status, CD status before and after infection, and clinical manifestations resulting from COVID-19, were evaluated.
RESULTS
Among the patients with COVID-19, three, who underwent Auto HSCT less than six months ago, relapsed and one, in addition to the CD symptoms, started to present thyroid impairment with positive anti-TPO. Only one of the patients required hospitalization for five days to treat COVID-19 and remained in CD clinical remission. Nine patients reported late symptoms that may be related to COVID-19. There were no deaths, and a statistical evaluation of the series of COVID-19 patients compared to those who did not present any infectious episode did not identify significant differences regarding the analyzed parameters.
CONCLUSION
Despite the change in CD status in three patients and the presence of nine patients with late symptoms, we can conclude that there was no significant adverse impact concerning COVID-19 in the evaluated patients who underwent HSCT to treat CD.
Analisis Penyebab Diselenggarakannya Pemungutan Suara Ulang (PSU) Di Provinsi Jawa Timur Tahun 2024
Authors: Irsyedha Alfara Reginantis  , Nadiah Aurahmadani Priyambodo  , Adam Jamal  
Published: April 2024

The research that we conducted has the aim of knowing the causes of the Re-voting (PSU) ini the 2024 simultaneous general elections in East Java. Aiming to see what factors are behind the PSU. This research was conducted to see the decisions making carried out by Bawaslu in handling allegations of fraud that occurd during the 2024 election process. With the aim of knowing the process in making decisions for organizing PSUs. The method used is qualitative with a literature study approach to collect data to conduct in-depth alaysis which is then presented in the form of a literacy that is useful for adding information to readers and can also be used to make considerations in every decision-making process when facing a problem. The emergence considerations in the form of re-voting is mentioned when a whole process of analyzing various reports, information and data obtained by the Regional Election Supervisory Committee has been carried out. The report willlater be used as basic evidence related to all findings of fraud in the implementation of elections that violate laws and regulations. So that information about the occurrence of these violations will be the cause behind the PSU based on Article 372 paragraphs (2) of Law Number 7 Year 2017 cencerning elections. Things like this should be prevented trough actions that have been taken by the government long before the implementation of the 2024 elections and supported by the organizing committee and election participants can understand the rules regarding the implementation of voting until the time the vote count is carried out.
Cardiomyocyte Maturation During Regeneration
Authors: Staff Editorial 
Published: April 2024

The interplay between calcium signaling and sarcomeres plays a crucial role in directing cardiomyocyte maturation during cardiac regeneration. During cardiac regeneration, various processes occur to restore damaged or lost cardiac tissue, including the proliferation and differentiation of precursor cells into functional cardiomyocytes. These newly formed cardiomyocytes undergo a maturation process to acquire the structural and functional characteristics of adult cardiomyocytes. Nguyen and colleagues found that the cardiac dyad, a structure that regulates calcium handling and excitation-contraction coupling, played a key role in the redifferentiation process. A component of the cardiac dyad called leucine-rich repeat-containing 10 (Lrrc10) acted as a negative regulator of proliferation, prevented cardiomegaly, and induced redifferentiation. They found that its function was conserved in mammalian cardiomyocytes. Their study highlights the importance of the underlying mechanisms required for heart regeneration and their application to the generation of fully functional cardiomyocytes. Science. 2023 May 19;380(6646):758-764. doi: 10.1126/science.abo6718.