bluuebunny/crossref_metadata_2025_split huggingface dataset:
Korean Addenbrooke's Cognitive Examination Revised (K‐ACER) for differential diagnosis of Alzheimer's disease and subcortical ischemic vascular dementia
Authors: Kwak Yong Tae , Yang Youngsoon , Kim Gyung Whan 
Published: May 2010

Aim:  Sensitive, specific neuropsychological screening tests, such as the Addenbrooke's Cognitive Examination Revised (ACE‐R), are essential for dementia diagnosis. We aimed to validate the use of the Korean version of ACE‐R (K‐ACER) to differentiate Alzheimer's disease (AD) from subcortical ischemic vascular dementia (SIVD).Methods:  Standard tests for dementia screening were applied to 156 subjects (84 controls, 30 AD, 42 SIVD), and total and sub‐domain scores on the K‐ACER, as well as the sub‐domain ratio (VLOM), were compared.Results:  The reliability of the K‐ACER was very good (α‐coefficient 0.84), and cut‐off score for dementia was determined (cut‐off value 78, sensitivity 0.93, specificity 0.95). The likelihood ratio for dementia was calculated as between 78 and 82. At a cut‐off of 78, the likelihood of dementia was 18.6:1. Although a comparison of K‐ACER scores between AD and SIVD patients revealed significant differences in verbal fluency, language domain and VLOM ratio, sensitivity and specificity for differential diagnosis between AD and SVID proved less accurate.Conclusion:  The K‐ACER is a rapid, sensitive and specific dementia screening test. Though sub‐domains of items may be useful for differentiating between AD and SIVD, sensitivity and specificity is less accurate than dementia screening itself. Geriatr Gerontol Int 2010; 10: 295–301.
Transition of cytomegalovirus seropositivity in Japanese puerperal women
Authors: Inde Yusuke , Yamaguchi Satoru , Kamoi Seiryu , Takeshita Toshiyuki 
Published: May 2010

AbstractAim:  To investigate the latest serological tendency of cytomegalovirus (CMV) in Japanese puerperal women and to estimate the sequential influence on child‐bearing women in Japan.Methods:  We studied 3966 puerperal women registered at a cord blood bank. Serum samples were obtained from umbilical cords at delivery and on the third day after delivery. CMV immunoglobulin G (IgG) and CMV immunoglobulin M (IgM) antibodies were determined using enzyme immunoassay kits. Scatter diagrams between seroprevalences and perinatal details were generated, and Pearson product‐moment correlation coefficients (r) and coefficients of determination (R2) were calculated.Results:  The overall CMV seroprevalence was 68.4% for the IgG antibody and 3.9% for the IgM antibody. IgM seroconversion had occurred separately in 0.28% of the cases without IgG seroconversion. Including outliers on scatter plots, linear decreasing trends were observed for IgG seropositivity with measurement year (r = −0.72, P < 0.05, R2 = 51.8%) and maternal birth year (r = −0.43, P < 0.05, R2 = 18.2%). There was a linear increasing tendency for IgG seroprevalence with maternal age (r = 0.46, P < 0.05, R2 = 21.4%). Without the outlier, a linear decreasing tendency was found for IgM seropositivity (r = −0.85, P < 0.01, R2 = 71.6%).Conclusion:  CMV seropositivity decreased with maternal youth in Japanese puerperal women. A possible contradiction was identified: decreasing tendencies in the seroprevalence of both IgG and IgM might coexist. We assume that actual CMV infections spread in a transient epidemic manner in which it may not be possible to observe a linear tendency and/or that the actual risk of maternal CMV infection might be decreasing.
The relationship of COX–2 expression with estrogen receptor, progesterone receptor and prognostic parameters in endometrial carcinomas
Authors: Keser Sevinç Hallaç , Gül Aylin Ege , Barışık Nagehan Özdemir , Çakır Çağlar , Şensu Sibel , Kandemir Nilüfer Onak , Karadayı Nimet 
Published: May 2010

AbstractAim:  Endometrial cancer (EC), which is the most common gynecologic cancer, develops as a result of disruption of the delicate balance between cell proliferation and cell loss, or apoptosis through activation of oncogenesis, or loss of tumor suppressor genes. Among the biochemical factors proposed to give a more detailed characterization of EC biology, estrogen receptors (ER) and progesterone receptors (PR) play a major role. Most of the studies in the literature have shown increased expression of cyclooxygenase‐2 (COX–2) in EC. Recent experiments suggest that COX–2 antagonizes cell apoptosis, increases the invasiveness of malignant cells and promotes angiogenesis. The aim of this study was to investigate the expression of COX–2 in EC, to study its correlation to established menstrual status, grade, myometrial invasion, lymph node status, stage and ER and PR status.Material & Methods:  The study was performed on 72 ECs. Immunohistochemically was analyzed for ER, PR, and COX–2.Results:  COX–2 positivity was found in 91.7% of the cases. In 61 cases (84.7%) there was ER positive staining, and in 59 cases (81.9%) PR positive staining was observed. We have not found a statistically significant relation between COX–2 and prognostic factors, ER and PR.Conclusions:  A high expression rate still suggests a probable relation with endometrial carcinogenesis. If such a relation exists, new therapeutic options might be available in the future.
Uterine junctional zone at magnetic resonance imaging: A predictor of in vitro fertilization implantation failure
Authors: Maubon Antoine , Faury Alexandre , Kapella Michel , Pouquet Magalie , Piver Pascal 
Published: May 2010

AbstractAim:  To prospectively study the influence of the uterine junctional zone thickness measured on pelvic magnetic resonance imaging (MRI), on implantation rates during in vitro fertilization (IVF).Methods:  A prospective clinical‐imaging study was conducted and included 152 female patients. Patients had a positive diagnosis of infertility and an indication for IVF. All patients had a pelvic MRI scan on a 1.5T magnet with T2‐weighted sequences prior to IVF. The average junctional zone thickness value and the maximal junctional zone thickness values were measured. Implantation outcomes were correlated with junctional zone values and with infertility subtypes (endometriosis, tubal, dysovulation, male, unexplained).Results:  The mean number of embryo transfers per patient was 1.63, with a total pregnancy rate of 54%. Junctional zone thickness increase was significantly correlated with implantation failure at IVF: implantation failure rate was 95.8% for patients with an average junctional zone superior to 7 mm and a maximal junctional zone superior to 10 mm, versus 37.5% in other patient groups (P < 0.0001), independently from the cause of infertility or patients' age.Conclusion:  In a group of infertile patients engaged in an IVF program, a pelvic MRI scan showing a thickened uterine junctional zone is a negative predictive factor for embryo implantation after IVF.
Late post‐cesarean surgical complication
Authors: Fawzy Muhammad , Zalata Khaled 
Published: May 2010

AbstractAim:  The aim of the study was to clarify the incidence, indication, and management of late surgical intervention following cesarean section (CS) in a tertiary care university hospital.Methods:  A cohort of 5981 women underwent CS from a group of 24 060 parturients in a retrospective study at a tertiary care university hospital. Surgical intervention after CS in the late postoperative period (after puerperium) was reviewed regarding clinical, operative, and pathological findings.Results:  The CS rate was 24.86%. The incidence of late surgical intervention after CS was 0.40% (24/5981); of these 24 women, 10 (41.67%) were operated for skin lesions, two (8.3%) for urogenital fistula, three (12.5%) for gastrointestinal problems, three (12.5%) for omental masses and six (25%) for pelvic lesions.Conclusion:  Although the incidence of surgical intervention after CS in the late postoperative period is low and the outcome is favorable, several measures must be undertaken to reduce late surgical complications.
Internal iliac artery ligation for severe postpartum hemorrhage and severe hemorrhage after postpartum hysterectomy
Authors: Camuzcuoglu Hakan , Toy Harun , Vural Mehmet , Yildiz Fahrettin , Aydın Halef 
Published: May 2010

AbstractAim:  The aim of this study was to evaluate the effect of internal iliac artery (IIA) ligation performed for severe postpartum hemorrhage (PPH).Methods:  Thirty‐three women who underwent IIA ligation to control PPH in a tertiary referral center between June 2007 and May 2009 were included in this retrospective analysis. IIA ligation was performed as the primary surgical intervention or to control bleeding following hysterectomy.Results:  The 33 women underwent IIA ligation due to uterine atony (n = 22), placenta previa accreta/increta/percreta (n = 5), uterine rupture (n = 4), and placental abruption (n = 2). Twenty‐four women underwent IIA ligation as the primary surgical intervention. IIA ligation resulted in control of bleeding in 18/24 women (75%), and only 6/24 women (25%) showed unsuccessful management of bleeding with IIA ligation. In the six women for whom the bleeding was not controlled with IIA ligation, hysterectomy was urgently performed before closure of the abdomen. After obtaining adequate hemostasis with IIA ligation, no women required relaparotomy in the postoperative period. Nine women with persistent bleeding following hysterectomy were also treated with IIA ligation. In our study, there were no intraoperative or postoperative complications related to the procedure.Conclusion:  IIA ligation may be an effective and safe treatment option to arrest severe PPH. This procedure may also be useful to arrest persistent hemorrhage after hysterectomy. Increased understanding of the retroperitoneal anatomy is needed to reduce the risk of intraoperative and postoperative serious complications.
Perceived risk of Type 2 diabetes in Australian women with a recent history of gestational diabetes mellitus
Authors: Morrison M. K. , Lowe J. M. , Collins C. E. 
Published: May 2010

Diabet. Med. 27, 882–886 (2010)AbstractAims  To describe the risk perceptions and factors associated with a high level of perceived risk for the development of Type 2 diabetes in a sample of Australian women with a recent history of gestational diabetes mellitus.Methods  Participants were women aged 18 years and over, diagnosed with gestational diabetes between 2003 and 2005, registered with the National Diabetes Services Scheme. Cross‐sectional data were collected via written postal survey and included a self‐reported risk perception scale.Results  Of 4098 invited, eligible women, 1372 consented to participate (response rate 36%). Respondents currently pregnant or subsequently diagnosed with Type 2 diabetes were excluded (n = 196). Up to 3 years post‐gestational diabetes, 32% of women perceived that they were at a low or very low risk for developing Type 2 diabetes, 42% at moderate risk and 26% high or very high risk. Using logistic regression analysis, factors associated with high level of perceived risk were body mass index > 25 kg/m2 [odds ratio (OR) 4.50, 95% confidence interval (CI) (3.12, 6.51)], a family history of diabetes [OR 3.80, 95% CI (2.67, 5.33)] and use of insulin during pregnancy [OR 1.92, 95% CI (1.31, 2.61)].Conclusions  Although women with known risk factors for Type 2 diabetes were more likely to perceive their risk as high, we found that one third still considered themselves to be at low or very low risk for the development of diabetes. These results suggest a need for increased awareness of gestational diabetes as a strong predictor of Type 2 diabetes risk.
Comparing risk profiles of individuals diagnosed with diabetes by OGTT and HbA1cThe Danish Inter99 study
Authors: Borg R. , Vistisen D. , Witte D. R. , Borch‐Johnsen K. 
Published: May 2010

Diabet. Med. 27, 906–910 (2010)AbstractAims  Glycated haemoglobin (HbA1c) has been proposed as an alternative to the oral glucose tolerance test for diagnosing diabetes. We compared the cardiovascular risk profile of individuals identified by these two alternative methods.Methods  We assessed the prevalence of cardiovascular risk factors in individuals with undiagnosed diabetes according to the World Health Organization classification or by the newly proposed HbA1c level ≥ 6.5% among 6258 participants of the Danish Inter99 study. Receiver operating curve analysis assessed the ability of fasting: 2‐h plasma glucose and HbA1c to distinguish between individuals at high and low risk of ischemic heart disease, predicted by the PRECARD program.Results  Prevalence of undiagnosed diabetes was 4.1% [95% confidence interval (CI) 3.7–4.7%] by the current oral glucose tolerance test definition, whereas 6.6% (95% CI 6.0–7.2%) had diabetes by HbA1c levels. HbA1c‐defined individuals were relatively older with higher proportions of men, smokers, lipid abnormalities and macro‐albuminuria, but they were leaner and had lower blood pressure. HbA1c was better than fasting‐ and 2‐h plasma glucose at distinguishing between individuals of high and low predicted risk of ischaemic heart disease; however, the difference between HbA1c and fasting‐ and 2‐h plasma glucose was not statistically significant.Conclusions  Compared with the current oral glucose tolerance test definition, more individuals were classified as having diabetes based on the HbA1c criteria. This group had as unfavourable a risk profile as those identified by the oral glucose tolerance test.
The Leicester Risk Assessment score for detecting undiagnosed Type 2 diabetes and impaired glucose regulation for use in a multiethnic UK setting
Authors: Gray L. J. , Taub N. A. , Khunti K. , Gardiner E. , Hiles S. , Webb D. R. , Srinivasan B. T. , Davies M. J. 
Published: May 2010

Diabet. Med. 27, 887–895 (2010)AbstractAims  Risk assessment scores identify those at high risk of impaired glucose regulation and Type 2 diabetes mellitus. To date no risk assessment scores that can be completed by a lay person have been developed and validated specifically for multiethnic populations in the UK.Methods  We used data on 6186 subjects aged 40–75 years from a multiethnic UK screening study (73% white European, 22% South Asian). All participants were given a 75 g oral glucose tolerance test. We developed logistic regression models for predicting current impaired glucose regulation (impaired fasting glycaemia/impaired glucose tolerance) or Type 2 diabetes mellitus using data from anthropometric measurements and self‐reported questionnaires. Using the best‐fitting model, we developed the Leicester Risk Assessment score. We externally validated the score using data from 3171 subjects aged 40–75 years from a separate screening study.Results  The components of the final model are age, ethnicity [white European vs. other (predominantly South Asian)], sex, first degree family history of diabetes, antihypertensive therapy or history of hypertension, waist circumference and body mass index. The score ranges from 0 to 47. Validating this model using the data from the second screening study gave an area under the receiver operator characteristic curve of 72% (95% confidence interval, 69–74%). A cut point of 16 had a sensitivity of 81% and a specificity of 45%.Conclusions  The Leicester Risk Assessment score can be used to identify those at high risk of impaired glucose regulation and Type 2 diabetes mellitus in UK multiethnic populations. The score is simple (seven questions) and non‐invasive.
Vasectomy within the public health services in Campinas, São Paulo, Brazil
Authors: Marchi N.M. , De Alvarenga A.T. , Osis M.J.D. , De Aguiar Godoy H.M. , Simões e Silva Domeni M.F. , Bahamondes L. 
Published: May 2010

MARCHI N.M., DE ALVARENGA A.T., OSIS M.J.D., DE AGUIAR GODOY H.M., SIMÕES E SILVA DOMENI M.F. & BAHAMONDES L. (2010) Vasectomy within the public health services in Campinas, São Paulo, Brazil. International Nursing Review57, 254–259Objective:  To describe some of the characteristics of men who underwent a vasectomy in the public health network of Campinas, São Paulo, Brazil.Methods:  A descriptive study including 202 men randomly selected from a list of all the men vasectomized between 1998 and 2004 in the public health network.Results:  Most of the men were 30 years of age or older when vasectomized, had completed elementary school and had two or more children of both sexes. Most of the men came from the lowest income segment of the population: 47.6% in 1998–1999 and 61.3% in 2003–2004. Although the men knew various contraceptive methods, 51.2% reported that their partners were using combined oral contraceptives at the time of surgery. Most men initially sought information on vasectomy at health‐care clinics where care was provided by a multidisciplinary team; most received counselling, however, 47.9% of the men waited more than 4 months for the vasectomy.Conclusions:  The profile of the vasectomized men in this study appears to indicate that the low‐income population from Campinas, São Paulo, Brazil has access to vasectomy; however, the waiting time for vasectomy reveals that difficulties exist in obtaining this contraceptive method in the public health service.
The evaluation of nurses and nursing activities through the perceptions of inpatients
Authors: Oflaz F. , Vural H. 
Published: May 2010

OFLAZ F. & VURAL H. (2010) The evaluation of nurses and nursing activities through the perceptions of inpatients. International Nursing Review57, 232–239Aim:  To examine the relationship of inpatients' perceptions and satisfaction statements with nurses and the nursing activities presented and to determine nursing activities that were implemented mostly from the view of inpatients.Background:  Nursing care is one of the fundamental components of health care, and studies have shown that it has a considerable influence on how patients experience hospitalization. However, nursing care is usually listed as one category in surveys. In fact, nursing care is an integrated combination of specific nursing activities, and to improve nursing practice we need to clarify how each nursing activity affects the perceptions of patients.Methods:  This descriptive study uses cross‐sectional survey design. The sample consists of 454 inpatients from a large‐scale teaching hospital in Ankara, Turkey. A questionnaire survey including demographics and perceptions of the patients, along with a list of the activities that nurses were required to carry out, were administered to the patients.Findings:  Age, gender and marital status were the variables influencing patients' perceptions. Technical nursing activities were recognized more by patients than activities related to care. All nursing activities were relevant to patient satisfaction statements. Most of the patients were satisfied with the nursing care despite the task‐oriented environment.Conclusions:  The results of this study show that nurses tend to do technical activities. All nursing activities were related to patient satisfaction statements. Nurses should be aware of the effect of each activity they are required to carry out on patients and the importance of good communication with patients.
Evaluation of an elderly care training programme for women
Authors: Bayik T.A. , Uysal A. 
Published: May 2010

BAYIK T.A. & UYSAL A. (2010) Evaluation of an elderly care training programme for women. International Nursing Review57, 240–246Background:  Caregiving across different cultures has been perceived conventionally as a private or family responsibility, predominantly performed by women who accept their caregiving as part of their gender role.Aim:  This study aimed to design, deliver, and evaluate an elderly training programme for women by assessing their knowledge, attitudes and skills as a lay caregiver. Encouraging the women to find suitable positions for employment in private or governmental institutions was the further objective of the study.Design:  The study was a quasi‐experimental one‐group pre‐test post‐test design.Methods:  The study was conducted in a solidarity centre for women and in a nursing home for the elderly. The sample covered 120 women selected from the community by convenience sampling. Data were gathered through pre‐ and post‐test evaluation and observation forms in 2 May–22 December 2005. The training programme consisted of 230 h of didactic sessions, demonstrations and clinical practices.Findings:  The mean change in the participants' knowledge score (pre‐test: 41.44 ± 0.92; post‐test: 71.16 ± 1.34) demonstrated a statistically significant improvement in their knowledge. According to clinical observations, most of them displayed satisfactory caring and communication skills towards the elderly. Virtually all participants reported increased skill, knowledge and confidence.Conclusion:  The developed training programme was effective, resulting in an increased knowledge, the acquisition of good attitudes towards the elderly, and performing satisfactory caring and communication skills. Similar community‐based programmes managed by nurses are recommended to support non‐professional caregivers. The research is not only an innovative but also a revolutionary model to promote women.
Global Government Health Partners' Forum 2006: eighteen months later
Authors: Foster J. , Guisinger V. , Graham A. , Hutchcraft L. , Salmon M. 
Published: May 2010

FOSTER J., GUISINGER V., GRAHAM A., HUTCHCRAFT L. & SALMON M. (2010) Global Government Health Partners' Forum 2006: eighteen months later. International Nursing Review57, 173–179Background:  The challenge of global health worker shortages, particularly among nurses, has been the topic of numerous forums over the last several years. Nevertheless, there has been little attention given to the roles of government chief nursing and medical officers as key partners in addressing health worker shortages. This partnership and its potential impact on the adequacy of the global health workforce was the focus of the most recent Global Government Health Partners (GGHP) Forum held in November 2006 in Atlanta, Georgia, USA. This forum was uniquely designed to create a context for government chief nursing officers and chief medical officers to engage in a joint learning and planning experience focused on positioning their leadership to impact health workforce issues.Aim:  This article describes an 18‐month follow‐up evaluation of the outcomes of the GGHP. The purpose of the evaluation was to assess the impact of the forum experience on the actions of participants based on the country‐level plans they produced at the forum. This important feedback is intended to inform the design of future partnered global forums and gain insights into the utility of forum‐based action plans. The evaluation process itself has served as an opportunity for the engagement of university faculty, students and staff in a global service learning experience.Conclusion:  The outcomes of this evaluation indicate that important progress has been made by countries whose leadership was involved in the forum, and was also an important learning activity for those participating in the conduct of the study.