bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between habitual coffee consumption and normal or increased estimated glomerular filtration rate in apparently healthy adults
Authors: Nakajima Kei , Hirose Kazuki , Ebata Midori , Morita Kumiko , Munakata Hiromi 
Published: September 2009

Habitual coffee consumption is associated with the prevention of type 2 diabetes, which often accompanies diabetic nephropathy. However, the relationship between coffee consumption and kidney function is unclear. Therefore, we investigated the associations between habitual coffee consumption and kidney function and damage assessed by the estimated glomerular filtration rate (eGFR) and proteinuria using dipstick urinalysis, respectively, in a cross-sectional study of 342 apparently healthy adults. Habitual coffee consumption was defined as drinking one or more cups of coffee per d. eGFR in coffee consumers (n182; 80·1 (sd15·0) ml/min per 1·73 m2) was significantly higher than that in non-coffee consumers (n160; 76·9 (sd12·6) ml/min per 1·73 m2) (P < 0·05). Multivariate logistic analysis showed that, compared with non-coffee consumption, coffee consumption was significantly associated with normal or increased eGFR (NIGFR) ( ≥ 90 ml/min per 1·73 m2), but not proteinuria, which was not attenuated, even after adjustment for age, sex, smoking, tea consumption and other cardiovascular risks (OR 2·91; 95 % CI 1·51, 5·61;P = 0·001). When we took into account eGFR measured 1 year before in a subgroup of the subjects (n262), coffee consumption (n142) had a significant relationship with eGFR, which was consistently higher with a difference of 4·0 ml/min per 1·73 m2compared with non-coffee consumption (P = 0·01; two-way repeated ANOVA). Similar associations were observed in both sexes when data were reanalysed according to sex. In conclusion, our findings suggest that habitual coffee consumption is associated with NIGFR independently of clinical confounders. Further studies are needed to confirm this association and to explore whether the effect of coffee consumption on eGFR is beneficial for the kidney.
Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient – a randomised, placebo-controlled trial
Authors: von Hurst Pamela R. , Stonehouse Welma , Coad Jane 
Published: September 2009

Low serum 25-hydroxyvitamin D (25(OH)D) has been shown to correlate with increased risk of type 2 diabetes. Small, observational studies suggest an action for vitamin D in improving insulin sensitivity and/or insulin secretion. The objective of the present study was to investigate the effect of improved vitamin D status on insulin resistance (IR), utilising randomised, controlled, double-blind intervention administering 100 μg (4000 IU) vitamin D3(n42) or placebo (n39) daily for 6 months to South Asian women, aged 23–68 years, living in Auckland, New Zealand. Subjects were insulin resistant – homeostasis model assessment 1 (HOMA1)>1·93 and had serum 25(OH)D concentration < 50 nmol/l. Exclusion criteria included diabetes medication and vitamin D supplementation >25 μg (1000 IU)/d. The HOMA2 computer model was used to calculate outcomes. Median (25th, 75th percentiles) serum 25(OH)D3increased significantly from 21 (11, 40) to 75 (55, 84) nmol/l with supplementation. Significant improvements were seen in insulin sensitivity and IR (P = 0·003 and 0·02, respectively), and fasting insulin decreased (P = 0·02) with supplementation compared with placebo. There was no change in C-peptide with supplementation. IR was most improved when endpoint serum 25(OH)D reached ≥ 80 nmol/l. Secondary outcome variables (lipid profile and high sensitivity C-reactive protein) were not affected by supplementation. In conclusion, improving vitamin D status in insulin resistant women resulted in improved IR and sensitivity, but no change in insulin secretion. Optimal vitamin D concentrations for reducing IR were shown to be 80–119 nmol/l, providing further evidence for an increase in the recommended adequate levels. Registered Trial No. ACTRN12607000642482.
Glycaemic index and glycaemic load values of a selection of popular foods consumed in Hong Kong
Authors: Lok Kris Y. , Chan Ruth , Chan Dicken , Li Liz , Leung Grace , Woo Jean , Lightowler Helen J. , Henry C. Jeya K. 
Published: September 2009

The objective of the present paper is to provide glycaemic index (GI) and glycaemic load (GL) values for a variety of foods that are commonly consumed in Hong Kong and expand on the international GI table of Chinese foods. Fasted healthy subjects were given 50 g of available carbohydrate servings of a glucose reference, which was tested twice, and test foods of various brands of noodles (n5), instant cereals (n3) and breads (n2), which were tested once, on separate occasions. For each test food, tests were repeated in ten healthy subjects. Capillary blood glucose was measured via finger-prick samples in fasting subjects ( − 5, 0 min) and at 15, 30, 45, 60, 90 and 120 min after the consumption of each test food. The GI of each test food was calculated geometrically by expressing the incremental area under the blood glucose response curve (IAUC) of each test food as a percentage of each subject's average IAUC for the reference food. GL was calculated as the product of the test food's GI and the amount of available carbohydrate in a reference serving size. The majority of GI values of foods tested were medium (a GI value of 56–69) to high (a GI value of 70 or more) and compared well with previously published values. More importantly, our dataset provides GI values of ten foods previously untested and presents values for foods commonly consumed in Hong Kong.
Low calcium:phosphorus ratio in habitual diets affects serum parathyroid hormone concentration and calcium metabolism in healthy women with adequate calcium intake
Authors: Kemi Virpi E. , Kärkkäinen Merja U. M. , Rita Hannu J. , Laaksonen Marika M. L. , Outila Terhi A. , Lamberg-Allardt Christel J. E. 
Published: September 2009

Excessive dietary P intake alone can be deleterious to bone through increased parathyroid hormone (PTH) secretion, but adverse effects on bone increase when dietary Ca intake is low. In many countries, P intake is abundant, whereas Ca intake fails to meet recommendations; an optimal dietary Ca:P ratio is therefore difficult to achieve. Our objective was to investigate how habitual dietary Ca:P ratio affects serum PTH (S-PTH) concentration and other Ca metabolism markers in a population with generally adequate Ca intake. In this cross-sectional analysis of 147 healthy women aged 31–43 years, fasting blood samples and three separate 24-h urinary samples were collected. Participants kept a 4-d food record and were divided into quartiles according to their dietary Ca:P ratios. The 1st quartile with Ca:P molar ratio ≤ 0·50 differed significantly from the 2nd (Ca:P molar ratio 0·51–0·57), 3rd (Ca:P molar ratio 0·58–0·64) and 4th (Ca:P molar ratio ≥ 0·65) quartiles by interfering with Ca metabolism. In the 1st quartile, mean S-PTH concentration (P = 0·021) and mean urinary Ca (U-Ca) excretion were higher (P = 0·051) than in all other quartiles. These findings suggest that in habitual diets low Ca:P ratios may interfere with homoeostasis of Ca metabolism and increase bone resorption, as indicated by higher S-PTH and U-Ca levels. Because low habitual dietary Ca:P ratios are common in Western diets, more attention should be focused on decreasing excessively high dietary P intake and increasing Ca intake to the recommended level.
Development of larvalContracaecum rudolphiiHartwich, 1964 (Ascaridida: Anisakidae) in experimentally infected goldfish (Carassius auratusL., 1758)
Authors: Dziekońska-Rynko J. , Rokicki J. , Gomułka P. 
Published: September 2009

AbstractLaboratory-bred goldfish were experimentally infected withContracaecum rudolphii, either directly (with nematode larvae) or indirectly via infected zooplankton. Intensity and prevalence of infection were markedly higher in fish exposed to the infected zooplankton than in goldfish exposed to nematode larvae. When transmitted to fish via the zooplankton, larvae developed much faster and, after 8 weeks, became firmly encysted in the intestine wall. The digestive tract of larvae isolated from the intestine wall showed a well-developed ventriculus, ventricular appendix and intestinal caecum. The mouth was surrounded by three lips. When free-living larvae induced infection, they rapidly penetrated the intestine wall and migrated to internal organs (e.g. liver). The primordial lips of those larvae were poorly visible, the ventricular appendix was short, and the intestinal caecum was absent. During the 10-week experiment, no encysted larvae were found in fish infected with free-living larvae.
The Uses of Books in a Late Mughal Takiyya: Persianate Knowledge Between Person and Paper
Authors: GREEN NILE 
Published: September 2009

AbstractThis paper addresses several questions that appear preliminary to understanding the circulation of knowledge in early modern India (circa1500 to 1800): What work did writing do? What was the relationship between writing and speaking? And what can our answers to these questions tell us about cultural formulations of ‘knowledge’ in this period? After addressing these questions on ‘modes’ of circulation, this paper turns to the more practical issue of ‘means’ of circulation, looking at the intersection between religious and bureaucratic patterns of the production and consumption of books in the absence of printing in Indian languages. Overall, the paper argues for early modernity as a period of tension and transition between ‘anthropocentric’ and ‘bibliocentric’ attitudes towards the location and thence circulation of knowledge in a Persianate context. The issues are exemplified by reference to the various and, at times, perplexing uses of books in an imperial dervish lodge ortakiyya.
Letters Home: Banaras pandits and the Maratha regions in early modern India
Authors: O'HANLON ROSALIND 
Published: September 2009

AbstractMaratha Brahman families migrated to Banaras in increasing numbers from the early sixteenth century. They dominated the intellectual life of the city and established an important presence at the Mughal and other north Indian courts. They retained close links with Brahmans back in the Maratha regions, where pressures of social change and competition for rural resources led to acrimonious disputes concerning ritual entitlement and precedence in the rural social order. Parties on either side appealed to Banaras for resolution of the disputes, raising serious questions about the nature of Brahman community and identity. Banaras pandit communities struggled to contain these disputes, even as the symbols of their own authority came under attack from the Mughal emperor Aurangzeb. By the early eighteenth century, the emergence of the Maratha state created new models of Brahman authority and community, and new patterns for the resolution of such disputes.
Case-control study on Puumala virus infection: smoking is a risk factor
Authors: VAPALAHTI K. , VIRTALA A.-M. , VAHERI A. , VAPALAHTI O. 
Published: September 2009

SUMMARYPuumala hantavirus (PUUV) is apparently transmitted to humans by inhalation of aerosolized secretions of carrier rodents (bank voles). The means of transmission and the associated risk factors are poorly defined. An epidemiological study during the peak of an epidemic season in Finland was conducted based on 282 acute clinical PUUV infections and 204 controls without PUUV infection or immunity. The main risk factors adjusted by age, sex and living environment were cigarette smoking [odds ratio (OR) 3·6, 95% confidence interval (CI) 2·1–5·9,P<0·0001] and buildings with holes allowing rodents to enter (OR 3·3, 95% CI 2·0–5·6); these results were similar in two subsets. Further, use of rodent traps (OR3·5, 95% CI 2·2–5·7) and handling firewood (OR 2·7, 95% CI 1·6–4·4) were associated with a risk. The risk attributed to smoking also remained high using simulated population controls with average smoking habits. The results suggest that hantavirus transmission occurs by inhalation mainly indoors and is dependent on the condition of the respiratory tract.
Epidemiology of group B streptococcus in Korean pregnant women
Authors: LEE B. K. , SONG Y. R. , KIM M. Y. , YANG J. H. , SHIN J. H. , SEO Y. S. , OH K. Y. , YOON H. R. , PAI S. Y. , FOXMAN B. , KI M. 
Published: September 2009

SUMMARYBetween January 2006 and May 2008, 2624 pregnant S. Korean women between 35–37 weeks gestation were screened for group B streptococcus (GBS). Resistance to antimicrobials was tested by disk diffusion and serotype determined using co-agglutination assays and microarray methods. Overall, 8% of pregnant women were colonized. Serotype III was the predominant serotype (43·8%), followed by serotypes V (20·3%), Ia (12·1%), and Ib (9·5%). GBS was frequently resistant to clindamycin (54·0%) and erythromycin (25·6%); 3·7% were resistant to cefazolin. More than three-quarters of serotype V were resistant to clindamycin or erythromycin or both, and 71% of serotype III were resistant to clindamycin but only 12% were resistant to erythromycin. GBS prevalence exceeded earlier reports by one-third. This is the first report of cefazolin resistance in Korea. These results underscore the need to establish screening measures and chemoprophylaxis guidelines regarding GBS infections in Korea.
Modelling the impact of one-dosevs. two-dose vaccination regimens on the epidemiology of varicella zoster virus in Australia
Authors: GAO Z. , GIDDING H. F. , WOOD J. G. , MacINTYRE C. R. 
Published: September 2009

SUMMARYWe examined the impact of one-dosevs. two-dose vaccination strategies on the epidemiology of varicella zoster virus (VZV) in Australia, using a mathematical model. Strategies were assessed in terms of varicella (natural and breakthrough) and zoster incidence, morbidity, average age of infection and vaccine effectiveness (VE). Our modelling results suggest that compared to a one-dose vaccination strategy (Australia's current vaccination schedule), a two-dose strategy is expected to not only produce less natural varicella cases (5%vs. 13% of pre-vaccination state, respectively) but also considerably fewer breakthrough varicella cases (only 11·4% of one-dose strategy). Therefore a two-dose infant vaccination programme would be a better long-term strategy for Australia.
Tense and verb raising in advanced L2 French
Authors: HERSCHENSOHN JULIA , ARTEAGA DEBORAH 
Published: September 2009

ABSTRACTTwo UG approaches to L2A propose different views of parameter resetting, depending on the capacity of interlanguage grammars to gain new values for uninterpretable functional features. Representational Deficit/Interpretability (e.g. Hawkins, 2003) maintains that parameter settings are limited to L1 values, whereas Full Access (e.g. Prévost & White, 2000) claims L2 parameter values may be gained; both assume initial transfer of L1 morphosyntactic settings. We examine verb morphosyntax of three advanced anglophone learners of L2 French, beginning with a description of the theoretical issues. We next report the study: the subjects, data collection and results. The final section discusses the data in terms of the two approaches, concluding that the results generally support FA over RD/I.
Second-person pronoun use in French language discussion fora
Authors: WILLIAMS LAWRENCE , VAN COMPERNOLLE RÉMI A. 
Published: September 2009

ABSTRACTThis article examines the use of second-person pronouns in on-line French language discussion fora, with specific focus onDoctissimoandMeilleur du chef, two fora from which approximately 400,000 words were collected for this corpus. Two hundred discussion threads (i.e., series of linked postings), with a minimum of fifteen postings (i.e., messages) and a maximum of twenty per thread, were analysed in three different ways in order to determine whethertu,vous-singular, or neither could be considered the default address pronoun. The results of the analysis suggest that whiletuis clearly preferred in many cases, its use has not become systematic.
Aprosodia Secondary to Right Hemisphere Damage
Authors: Rodriguez Amy D. 
Published: September 2009

AbstractPurpose: This article introduces two types of prosody in human communication; describes right hemisphere contributions to prosody; describes prosodic deficits associated with right hemisphere damage; and discusses prevalence, quality of life, spontaneous recovery, and treatment of aprosodia.Method: Definitions of affective and linguistic prosody and aprosodia are provided. Results of lesion studies and neuroimaging studies are reviewed to inform the reader of the importance of the right hemisphere in prosody expression and comprehension, as well as to describe patterns of prosodic deficits in individuals with right hemisphere damage.Results and Conclusions: There is a large body of evidence supporting the role of the right hemisphere in affective prosody comprehension and production. Specifically, frontal brain regions and the basal ganglia are associated with aprosodia, suggesting there may be an underlying motor impairment. Because aprosodia is enduring and can impact quality of life, it is important to gain a better understanding of this disorder so that clinicians can accurately diagnose prosodic deficits and provide informed treatment.
Acoustic Correlates of Prosodic Abnormality in Acquired Apraxia of Speech
Authors: Jacks Adam 
Published: September 2009

Abstract
Purpose: Prosodic abnormality is one of the primary characteristics used for the perceptual differentiation between acquired apraxia of speech (AOS) and phonemic paraphasias in the context of fluent aphasia. Acoustic measures of speech prosody are not frequently used in the clinical assessment of AOS, but would be useful as a method of quantifying prosodic abnormality. The purpose of this paper is to describe acoustic characteristics of prosodic abnormality in adult speakers with AOS.
Method: Previous investigations of acoustic measures of speech prosody in AOS were reviewed, focusing on studies of duration, fundamental frequency (F0), and speech intensity.
Results and Conclusions: Prosodic abnormality in adults with AOS is primarily characterized by articulatory prolongation. In some individuals, relational patterns among syllables are retained despite overall increased duration, while others produce syllables that are temporally isolated, giving the impression that speech is programmed one syllable at a time. Syllable segregation is also noted in F0 and intensity contours that lack continuity across syllables. Metrics are suggested for use in quantification of prosodic abnormality in AOS. The review of findings, particularly slowed speech rate, is interpreted in the context of theoretical models of speech including impaired or intact feedback mechanisms in speakers with AOS.
Dysprosody and the Foreign Accent Syndrome
Authors: Haley Katarina L. 
Published: September 2009

Abstract
Purpose: The sudden emergence of a foreign accent in an individual's native language has been described in the literature for over 60 years. In one of the most famous cases, the terms prosody and dysprosody first were introduced to the literature. The purpose of this paper is to summarize the prosodic changes seen in the foreign accent syndrome (FAS) and to review its etiology and clinical course.
Method: Case studies were reviewed, with an emphasis on information about clinical presentation and course and on speech changes affecting stress, rate, duration, and intonation.
Results and Conclusions: In the majority of published cases with FAS, there has been documented focal brain injury in the left cerebral hemisphere, and the foreign accent has emerged after a period of recovery from muteness, nonfluent aphasia, and/or motor speech disorder. In other cases, a psychogenic etiology has been established or suggested. Stress, rate, and duration changes are similar to those seen in nonfluent aphasia and apraxia of speech, whereas intonation changes are more specific to the foreign accent presentation. Information about recovery and psychosocial consequences of the accented speech is sparse and these areas are in need of further study. In particular, there is a need for detailed and clinically oriented case studies with longitudinal follow-up.
Prosodic Impairment Associated With Traumatic Brain Injury
Authors: Irwin Billy 
Published: September 2009

Abstract
Purpose: This article discusses impaired prosody production subsequent to traumatic brain injury (TBI). Prosody may affect naturalness and intelligibility of speech significantly, often for the long term, and TBI may result in a variety of impairments.
Method: Intonation, rate, and stress production are discussed in terms of the perceptual, physiological, and acoustic characteristics associated with TBI.
Results and Conclusions: All aspects of prosodic production are susceptible to the effects of damage resulting from TBI. There are commonly associated prosodic impairments; however, individual variations in specific aspects of prosody require detailed analysis.
The implementation of routine outcome measures in a Tier 3 Psychological Therapies Service: The process of enhancing data quality and reflections of implementation challenges
Authors: Rao Amra S. , Hendry Gemma , Watson Robert 
Published: September 2009

AbstractBackground: The Newham Psychological Therapies Service (PTS) has been using the CORE System of evaluation to demonstrate effectiveness since 2004. More recently there has been the national and local drive to improve outcomes as outlined by a number of Department of Health policies and the Improving Access to Psychological Therapies (IAPT) initiative. Aims: This paper describes how, as a secondary care complex mental health service, we have engaged with the process of outcome measurement through complementing the usage of the CORE System with additional measures forming the service pilot minimum dataset. The process of implementation is outlined along with reflections on the challenges which the service faced in introducing outcome measurement. Findings: Engagement with outcome measurement by a service requires attention to be paid to the organisational and professional aspects and personal resonances for clinicians if it is to become established as a meaningful enterprise within secondary care services. Despite success at this task, challenges remain to the further development of this area of work.
Who drops‐out? Do measures of risk to self and to others predict unplanned endings in primary care counselling?
Authors: Saxon David , Ricketts Tom , Heywood Joanna 
Published: September 2009

AbstractAims: Unplanned endings, where clients unilaterally end therapy, are of concern for psychological therapy services generally as they raise questions about the appropriateness of the treatment and it's delivery for some clients. Limited available data indicates that those who drop‐out often have more severe symptoms at entry, and have poorer clinical outcomes. This raises further questions about risk to self and others for those clients who leave therapy prematurely and how these clients might be identified and kept engaged. Method: This paper uses a large dataset of CORE data collected routinely in a primary care counselling service between 2000 and 2003. Logistic regression was utilised to consider different measures of risk and other client characteristics recorded at assessment to predict drop‐out from the service. Results: These indicate that younger age, greater psychological distress at assessment, an addiction problem and greater risk to others, are associated with an unplanned ending. However, no reliable logistic regression model could be produced. This may be partly due to data quality issues or important characteristics not being available in the data. Implications for practice: The paper concludes that counsellors should actively seek to minimise unplanned endings, as amongst them may be represented the more distressed and risky clients referred to primary care counselling.