bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aktualisierung der DEGAM-S1-Handlungsempfehlung zum chronischen, nichttumorbedingten Schmerz
Authors: Straßner Cornelia , Becker Annette 
Published: May 2024

Zusammenfassung
Hintergrund
Gemäß den Vorgaben der Arbeitsgemeinschaft Wissenschaftlicher Medizinischer Fachgesellschaften (AWMF) erforderte die S1-Handlungsempfehlung „Chronischer Schmerz“ der Deutschen Gesellschaft für Allgemeinmedizin und Familienmedizin (DEGAM) eine Aktualisierung.

Methoden
Es erfolgte eine unsystematische selektive Literaturrecherche und eine Kommentierung durch die DEGAM-Leitlinienkommission.

Ergebnisse
Die inhaltlichen Aussagen der Vorversion können weitgehend aufrechterhalten werden. Es erfolgten inhaltliche Vertiefungen insbesondere in den Bereichen Assessment, nichtmedikamentöse Therapieansätze bzw. Self-Care- und Opioidmanagement. Die Kurzversion wurde um ein Dokument mit Erläuterungen und Implementierungshilfen ergänzt.

Schlussfolgerungen
Chronischer nichttumorbedingter Schmerz (CNTS) ist ein sehr häufiger Beratungsanlass in hausärztlichen Praxen. Handlungsempfehlungen und Instrumente speziell für das hausärztliche Setting werden dringend benötigt. Ein Upgrade der Handlungsempfehlung auf S2- oder S3-Leitlinien-Niveau und Praxishilfen für die gemeinsame Entscheidungsfindung zur individuellen Langzeitbegleitung von betroffenen Patient:innen sind für die Zukunft wünschenswert.
Recent efforts on investigating the effects of recycled rubber content on the mechanical properties of structural concrete
Authors: Eissa Mahmoud , Habib Ahed , AL Houri Ausamah , Alibrahim Bashar 
Published: May 2024

AbstractRubberized concrete effectively prevents brittle failures and enhances the ductility and energy absorption of concrete. It has been observed that the inclusion of rubber reduces the strength and abrasion resistance of concrete; however, the enhancement in energy absorption is significant. A vast number of tires end up as waste, posing a major environmental issue globally. The disposal of waste tires has become an acute environmental challenge, with billions discarded and buried worldwide, representing a significant ecological threat. Consequently, utilizing rubber in the concrete industry can be advantageous for both the environment and the industry. This study presents an extensive review of the effects of various rubber contents on the mechanical properties of concrete. The scope of the review encompasses an analysis of a diverse range of studies conducted over the past decade, focusing on the influence of rubber content on concrete's mechanical performance. The analysis revealed that the optimal amount of rubber to be used in concrete is in the range of 2–5% as a replacement for natural concrete aggregate. Furthermore, replacing aggregate with treated rubber may offer additional benefits, including improved energy absorption and sustainability. However, despite the promising benefits of rubberized concrete, there is a notable gap in the literature regarding the creep behavior of rubberized concrete, a crucial parameter for defining concrete performance, particularly in superstructures. This gap underscores the need for further research to comprehensively understand the long-term behavior of rubberized concrete under sustained loading conditions. Additionally, while coating or treating rubber could mitigate the reduction in mechanical properties associated with rubber inclusion, there remains a need for more investigation into the brittleness index and energy absorption of treated rubber. Addressing these gaps in knowledge will contribute to a more thorough understanding of the potential applications and limitations of rubberized concrete in various engineering contexts.
Clinical decision support menu for reducing unnecessary urine cultures
Authors: Stensgard Erik , Masoud Bobbie , Gravely Amy , Drekonja Dimitri 
Published: May 2024

Abstract
A clinical decision support menu requiring selection of urine culture (UC) indication within outpatient and inpatient settings of a large integrated health care system significantly reduced UC sample collection. Clear documentation of selected UC indication in most post-intervention cases affirms its potential as an effective diagnostic stewardship strategy.
Candida auris in the burn unit: a prolonged biphasic outbreak
Authors: Pedersen Laura , Mikesell Jake , Marcaccini Robert , Atkinson Connie , Cooper Kaila , Feldman Michael , Rittman Barry , Ching Patrick , Bryson Alexandra , Doll Michelle 
Published: May 2024

Abstract
Candida auris is an emerging pathogen responsible for healthcare-associated infections and outbreaks. This organism has a high tolerance to both high temperatures and high salinity. We describe our experience with a C. auris outbreak in an 8-bed inpatient burn unit at an academic medical center.
Proactive risk stratification and low-risk penicillin allergy delabeling by an antimicrobial stewardship pharmacist
Authors: Caturano Breana N. , Bjork Lauren L. , Lichtenberger Paola N. , Temiño Viviana M. 
Published: May 2024

Abstract
Penicillin (PCN) allergy delabeling is an important component of antimicrobial stewardship; however, widespread implementation has lagged. We found that most patients had low-risk PCN allergy histories eligible for delabeling without skin testing. Pharmacist-led risk stratification and drug challenge expanded access to delabeling independently from an Allergy/Immunology service.
Development and implementation of a nationwide multidrug-resistant organism tracking and alert system for Veterans Affairs medical centers
Authors: Pfeiffer Christopher D. , Jones Makoto M. , Klutts James S. , Francis Quinn A. , Flegal Hannah M. , Murray Adrienne O. , Willson Tina M. , Hicks Natalie R. , Evans Charlesnika T. , Evans Martin E. 
Published: May 2024

AbstractObjective:Develop and implement a system in the Veterans Health Administration (VA) to alert local medical center personnel in real time when an acute- or long-term care patient/resident is admitted to their facility with a history of colonization or infection with a multidrug-resistant organism (MDRO) previously identified at any VA facility across the nation.Methods:An algorithm was developed to extract clinical microbiology and local facility census data from the VA Corporate Data Warehouse initially targeting carbapenem-resistant Enterobacterales (CRE) and methicillin-resistant Staphylococcus aureus (MRSA). The algorithm was validated with chart review of CRE cases from 2010-2018, trialed and refined in 24 VA healthcare systems over two years, expanded to other MDROs and implemented nationwide on 4/2022 as “VA Bug Alert” (VABA). Use through 8/2023 was assessed.Results:VABA performed well for CRE with recall of 96.3%, precision of 99.8%, and F1 score of 98.0%. At the 24 trial sites, feedback was recorded for 1,011 admissions with a history of CRE (130), MRSA (814), or both (67). Among Infection Preventionists and MDRO Prevention Coordinators, 338 (33%) reported being previously unaware of the information, and of these, 271 (80%) reported they would not have otherwise known this information. By fourteen months after nationwide implementation, 113/130 (87%) VA healthcare systems had at least one VABA subscriber.Conclusions:A national system for alerting facilities in real-time of patients admitted with an MDRO history was successfully developed and implemented in VA. Next steps include understanding facilitators and barriers to use and coordination with non-VA facilities nationwide.
Co-ethnic Migration of Vojvodina Slovaks to Slovakia: Institutional Frameworks and Everyday Practices of Interaction
Authors: Zlatanović Sanja , Marušiak Juraj 
Published: May 2024

Abstract
In this article, we explore intra-ethnic aspects of co-ethnic migration by members of the Slovak community from Serbia to Slovakia, both at the institutional level and at the level of intra-ethnic relations, and the boundaries between migrants and the established population. In the first part, we focus on the institutional framework of co-ethnic migration: the politicization of diaspora issues in Slovakia, the Slovak community in Serbia in the hierarchy of Slovakia’s diaspora policy, and co-ethnic relations as a subject of negotiations. In the second part, we investigate the role of language in co-ethnic migration, the situation of nonrecognition by co-ethnics in Slovakia, intra-ethnic boundary-making in everyday interactions, and the consequences of migration on intra-ethnic relations among those members of the community who did not migrate. We thus analyze the ongoing migration of the Slovaks of Vojvodina from Serbia into Slovakia, from the early 1990s onward, through a blend of perspectives “from above” and “from below.” This article is based on extensive fieldwork conducted among members of the Vojvodina Slovak community, both migrants and non-migrants who have remained in Vojvodina. Thus, the sending country (Serbia) and the receiving country (Slovakia) represent one research field. The data collected in the field have been complemented by legal documents and statistical data to gain an overview of the wider social and political structures within which the migration is taking place.
Low soil phosphorus availability has limited effects on wood traits in young plants of five eucalypt species
Authors: Silva Franklin Magnum de Oliveira , Gioppato Helena Augusto , Borghi Alexandre Augusto , Andrade Sara Adrián López , Mazzafera Paulo 
Published: May 2024

Summary
Plant-derived products rely heavily on the availability of phosphorus (P) in the soil. With reserves of P-rocks being limited, there is a growing demand to enhance the efficiency of P utilization by crops. Eucalypts, an important economic crop in many countries, is a source of timber, coal, essence oils, and cellulose. After identifying low P tolerant and susceptible species in a previous study, we explored the various physiological and biochemical responses of these same species to low P availability. The aim was to expand our understanding of how different P-nutrition responses might impact eucalypt wood production and traits related to its quality. Our results indicate that low soil P minimally affects physiological wood parameters in the young trees of Eucalyptus acmenoides, Corymbia maculata, E. grandis, E. globulus, and E. tereticornis. Decreases in cellulose contents and increases in lignin content and syringyl and guaiacyl (S/G) ratios were observed under low P and only in E. acmenoides plants. Wood density remained unaffected in all species. Additionally, bark, stem, and root P concentrations increased under sufficient P conditions in E. globulus, E. grandis, and E. tereticornis. These findings suggest that these plant parts may act as reserve pools of this nutrient.
Larger putamen in individuals at risk and with manifest bipolar disorder
Authors: Thomas-Odenthal Florian , Stein Frederike , Vogelbacher Christoph , Alexander Nina , Bechdolf Andreas , Bermpohl Felix , Bröckel Kyra , Brosch Katharina , Correll Christoph U. , Evermann Ulrika , Falkenberg Irina , Fallgatter Andreas , Flinkenflügel Kira , Grotegerd Dominik , Hahn Tim , Hautzinger Martin , Jansen Andreas , Juckel Georg , Krug Axel , Lambert Martin , Leicht Gregor , Leopold Karolina , Meinert Susanne , Mikolas Pavol , Mulert Christoph , Nenadić Igor , Pfarr Julia-Katharina , Reif Andreas , Ringwald Kai , Ritter Philipp , Stamm Thomas , Straube Benjamin , Teutenberg Lea , Thiel Katharina , Usemann Paula , Winter Alexandra , Wroblewski Adrian , Dannlowski Udo , Bauer Michael , Pfennig Andrea , Kircher Tilo 
Published: May 2024

AbstractBackground:Individuals at risk for bipolar disorder (BD) have a wide range of genetic and non-genetic risk factors, like a positive family history of BD or (sub)threshold affective symptoms. Yet, it is unclear whether these individuals at risk and those diagnosed with BD share similar gray matter brain alterations.Methods:In 410 male and female participants aged 17–35 years, we compared gray matter volume (3T MRI) between individuals at risk for BD (as assessed using the EPIbipolar scale; n = 208), patients with a DSM-IV-TR diagnosis of BD (n = 87), and healthy controls (n = 115) using voxel-based morphometry in SPM12/CAT12. We applied conjunction analyses to identify similarities in gray matter volume alterations in individuals at risk and BD patients, relative to healthy controls. We also performed exploratory whole-brain analyses to identify differences in gray matter volume among groups. ComBat was used to harmonize imaging data from seven sites.Results:Both individuals at risk and BD patients showed larger volumes in the right putamen than healthy controls. Furthermore, individuals at risk had smaller volumes in the right inferior occipital gyrus, and BD patients had larger volumes in the left precuneus, compared to healthy controls. These findings were independent of course of illness (number of lifetime manic and depressive episodes, number of hospitalizations), comorbid diagnoses (major depressive disorder, attention-deficit hyperactivity disorder, anxiety disorder, eating disorder), familial risk, current disease severity (global functioning, remission status), and current medication intake.Conclusions:Our findings indicate that alterations in the right putamen might constitute a vulnerability marker for BD.
International Relations and the non-human: Exploring animal culture for global environmental governance
Authors: Lappe-Osthege Teresa , Duffy Rosaleen 
Published: May 2024

Abstract
There is a paradox in global environmental governance that policymaking must ‘follow the science’ while environmental change is itself characterised by scientific uncertainty. This paper addresses this paradox by embracing that uncertainty. We bring International Relations (IR) into conversation with animal studies to further develop conceptual debates on integrating non-human actors. We focus on avian cultures to understand the nexus between bird crime, flyways, and global environmental governance. We analyse how bird migrations along flyways disrupt mainstream systems of knowledge production that global conventions rely on. Zooming in on bird crime along flyways, we demonstrate that crime relies on offenders’ understanding of avian cultures. We synthesise those findings with an analysis of the Convention on Migratory Species, as the only global convention that integrates animal cultures to develop more effective responses to wildlife crime. Our analysis demonstrates that international conservation overlooks the exploitation of avian culture for criminal activity, rendering policy responses less effective, particularly in contexts of scientific uncertainty. Integrating animal cultures can address scientific uncertainty and promote multispecies learning, creating more effective forms of global environmental governance. Ultimately, this renders the non-human visible and makes it possible to explore the implications for multispecies entanglements in IR.
Analysis and forecasting of syphilis trends in mainland China based on hybrid time series models
Authors: Wang Zhen D. , Yang Chun X. , Zhang Sheng K. , Wang Yong B. , Xu Zhen , Feng Zi J. 
Published: May 2024

Abstract
Syphilis remains a serious public health problem in mainland China that requires attention, modelling to describe and predict its prevalence patterns can help the government to develop more scientific interventions. The seasonal autoregressive integrated moving average (SARIMA) model, long short-term memory network (LSTM) model, hybrid SARIMA-LSTM model, and hybrid SARIMA-nonlinear auto-regressive models with exogenous inputs (SARIMA-NARX) model were used to simulate the time series data of the syphilis incidence from January 2004 to November 2023 respectively. Compared to the SARIMA, LSTM, and SARIMA-LSTM models, the median absolute deviation (MAD) value of the SARIMA-NARX model decreases by 352.69%, 4.98%, and 3.73%, respectively. The mean absolute percentage error (MAPE) value decreases by 73.7%, 23.46%, and 13.06%, respectively. The root mean square error (RMSE) value decreases by 68.02%, 26.68%, and 23.78%, respectively. The mean absolute error (MAE) value decreases by 70.90%, 23.00%, and 21.80%, respectively. The hybrid SARIMA-NARX and SARIMA-LSTM methods predict syphilis cases more accurately than the basic SARIMA and LSTM methods, so that can be used for governments to develop long-term syphilis prevention and control programs. In addition, the predicted cases still maintain a fairly high level of incidence, so there is an urgent need to develop more comprehensive prevention strategies.
International travel as a risk factor for gastrointestinal infections in residents of North East England
Authors: Love Nicola K. , Jenkins Claire , McCarthy Noel , Baker Kate S. , Manley Petra , Wilson Deborah 
Published: May 2024

Abstract
International travel is thought to be a major risk factor for developing gastrointestinal (GI) illness for UK residents. Here, we present an analysis of routine laboratory and exposure surveillance data from North East (NE) England, describing the destination-specific contribution that international travel makes to the regional burden of GI infection.
Laboratory reports of common notifiable enteric infections were linked to exposure data for cases reported between 1 January 2013 and 31 December 2022. Demographic characteristics of cases were described, and rates per 100,000 visits were determined using published estimates of overseas visits from the Office for National Statistics (ONS) International Passenger Survey (IPS).
About 34.9% of cases reported international travel during their incubation period between 2013 and 2022, although travel-associated cases were significantly reduced (>80%) during the COVID-19 pandemic. Between 2013 and 2019, half of Shigella spp. and non-typhoidal Salmonella infections and a third of Giardia sp., Cryptosporidium spp., and Shiga toxin-producing Escherichia coli (STEC) infections were reported following travel. Rates of illness were highest in travellers returning from Africa and Asia (107.8 and 61.1 per 100,000 visits), with high rates also associated with tourist resorts like Turkey, Egypt, and the Dominican Republic (386.4–147.9 per 100,000 visits).
International travel is a major risk factor for the development of GI infections. High rates of illness were reported following travel to both destinations, which are typically regarded as high-risk and common tourist resorts. This work highlights the need to better understand risks while travelling to support the implementation of guidance and control measures to reduce the burden of illness in returning travellers.
Anaesthesia management of interventional cardiac catheterisation for pulmonary atresia with intact ventricular septum and critical pulmonary stenosis: a retrospective analysis
Authors: Zhang Xu , Zhang Ning , Wang Kui-liang , Ren Yue-yi 
Published: May 2024

AbstractObjective:Pulmonary atresia with intact ventricular septum and critical pulmonary stenosis usually have to undergo treatment in the neonatal period. Compared to traditional surgical intervention, catheter-based cardiac interventions may achieve similar or superior outcomes for neonates with pulmonary atresia with intact ventricular septum and critical pulmonary stenosis. However, there is limited literature on anaesthesia techniques, challenges, and risks associated with cardiac catheterisation in this population.Methods:This article retrospectively analysed the clinical data of pulmonary atresia with intact ventricular septum and critical pulmonary stenosis neonates who were treated with interventional cardiac catheterisation in our hospital from January 2015 to October 2022. Clinical outcomes considered were haemodynamic or pulse oxygen saturation instability, vasoactive requirements, prolonged intubation (>24 h postoperatively), and cardiovascular adverse events.Results:A total of 63 patients met the inclusion criteria. All patients survived the intervention. Among the patients with critical pulmonary stenosis, 40 successfully received percutaneous balloon pulmonary valvuloplasty, while three patients received ductal stenting due to moderate right ventricular dysplasia at the same time. For patients with pulmonary atresia with intact ventricular septum, 17 of the 23 patients successfully underwent percutaneous pulmonary valve perforation and percutaneous balloon pulmonary valvuloplasty. Of these, five patients underwent ductal stenting due to unstable pulmonary blood flow. Three patients only underwent ductal stenting. In addition, three patients received hybrid therapy.Conclusions:There are various clinical techniques and risk challenges in the interventional cardiac catheterisation of neonatal pulmonary atresia with intact ventricular septum and critical pulmonary stenosis. However, by mastering the physiological and pathophysiological characteristics of the disease, adequately preparing for the perioperative period, and predicting the procedure process and potential complications, anaesthesia and surgical risks can be effectively managed.
Political scientists' Track II diplomacy: the International Political Science Association and Cross-Strait relations
Authors: Feng John 
Published: May 2024

AbstractThe International Political Science Association (IPSA) is a unique case against the common perception that Beijing has the upper hand when the two regimes by the Taiwan Strait contest to join international (non-governmental) organisations. Beijing relentlessly pushes international organisations to acknowledge the One China principle; Taipei also relentlessly denies this principle while it seeks to join. In the 1980s, Chinese and Taiwanese political scientists, representing their own regimes, applied Track II diplomacy to compete over membership of this organisation. IPSA membership mattered to both regimes and their political scientists. After many years of Track II competition, The Chinese Association of Political Science in Taipei became a “collective” member without compromising on how to name itself in April 1989. As a result, Beijing's counterpart withdrew from the IPSA. This situation has now persisted for over thirty years. The IPSA case not only challenges the current understanding of Cross-Strait relations but also throws light on the theoretical understanding of Track II diplomacy.
The Ancient Configuration of the Southern Central Andes and Paleogeographic Reconstruction of the Late Cretaceous Foreland Basin at 34°40’S
Authors: Martos F. E. , Fennell L. M. , Naipauer M. , Valencia V. , Folguera A. 
Published: May 2024

AbstractThe early stages of Andean construction have been barely recognized due to a long history of tectonic superposition during the growth of the orogen. In this work, we present a multi‐method approach integrating sedimentological, geochronological, structural, and provenance analyses to reconstruct the architecture of the Late Cretaceous foreland basin at 34°40’S. We identified a new depocenter located in an inner position of the Late Cretaceous foreland basin, a strategic location to understand the sedimentation dynamics near the topographic front of the orogen. Two sandstone samples from the basal and upper sections of the Diamante Formation were collected for detrital zircons dating, which yielded maximum depositional ages between 98 Ma and 91 Ma. The provenance analyses based on U‐Pb zircons ages indicated a main source area located to the west, in the incipient orogenic belt, with a complementary contribution from basement rocks, located to the east. Moreover, growth strata documented in these deposits were compared with structural kinematic models, which suggest that some of these deposits are associated with inherited structures, reactivated during the tectonic inversion of the extensional Jurassic Atuel depocenter. Our paleogeographic model comprises an Andean Cordillera flanked by a hinterland basin to the west and a foreland basin to the east, with a deformational front positioned further east compared to previous models.