bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of fuzzy neural network‐based robust gain scheduling controllers
Authors: Sato Yoshishige 
Published: August 2009

AbstractThis paper proposes a method of robust gain scheduling control design by intelligent control that uses a fuzzy neural network without a model. We create a system that is robust and capable of automatic gain control against the conventional fixed PID control system, design a neural network which learns inverse dynamics as feedforward compensation, along with a two‐degree‐of‐freedom control to perform feedback compensation, produce a control system which adaptively adjusts the gain according to changes of the target errors, and verify the effectiveness of the proposed method. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(4): 21–28, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20820
Study of drive system for linear induction motor using magnetic energy recovery switch
Authors: Isobe Takanori , Takaku Taku , Kitahara Tadayuki , Sumitani Hideo , Shimada Ryuichi 
Published: August 2009

AbstractThis paper proposes a power supply suitable for driving linear induction motors. The power supply consists of a voltage source inverter (VSI) and a magnetic energy recovery switch (MERS). Circuit configuration and operation principles of the power supply are described. Power factor correction by MERS can increase the output power. Technical advantages of using MERS compared with increasing the rated voltage of VSI are discussed. Some experiments with a linear induction motor were conducted. The results confirm that MERS can reduce the capacity of the VSI or increase the output with the same VSI capacity. The number of devices and magnitude of losses are evaluated on a large‐scale drive system. A half‐bridge type of MERS is provided and discussed. The half‐bridge MERS mitigates disadvantages of using MERS. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(4): 65–74, 2009; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/eej.20832
An information system development method connecting business process modeling and its experimental evaluation
Authors: Okawa Tsutomu , Kaminishi Tsukasa , Kojima Yoshiyuki , Hirabayashi Syuichi , Koizumi Hisao 
Published: August 2009

AbstractBusiness process modeling (BPM) is gaining attention as a measure for analysis and improvement of the business process. BPM analyzes the current business process as an As‐Is model and solves problems to improve the current business, and also aims to create a business process that produces value as a To‐Be model. However, research into techniques that connect the business process improvement acquired by BPM to the implementation of the information system seamlessly is rarely reported. If the business model obtained by BPM is converted to UML, and the implementation can be carried out by the technique of UML, one can expect an improvement in the efficiency of information system implementation. In this paper, we describe a method for system development that converts the process model obtained by BPM into UML. The method is evaluated by modeling a prototype of a parts procurement system. In the evaluation, a comparison with a case in which the system is implemented using the conventional UML techniques without BPM is performed. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(4): 9–20, 2009; Published online in Wiley InterScience (www.interscience.wiley. com). DOI 10.1002/eej.20856
Simulation of variable‐speed wind generation system using boost converter of permanent magnet synchronous generator
Authors: Ohyama Kazuhiro , Sakamoto Tsuyoshi , Arinaga Shinji , Yamashita Yukio 
Published: August 2009

AbstractThis paper proposes a variable‐speed wind generation system using the boost converter. The proposed system has three speed control modes for the wind velocity. The control mode of low wind velocity regulates the armature current of the generator with the boost converter to control the speed of wind turbine. The control mode of middle wind velocity regulates the DC link voltage with the vector controlled inverter to control the speed of wind turbine. The control mode of high wind velocity regulates the pitch angle of the wind turbine with the pitch angle control system to control the speed of the wind turbine. The hybrid combination of three control modes extends the variable‐speed range. The proposed system simplifies maintenance, improves reliability, and reduces the costs compared with the variable‐speed wind generation system using a PWM converter.This paper describes the control strategy and modeling for a simulation of the proposed system using Simulink of Matlab. It also describes the control strategy and modeling of a variable‐speed wind generation system using a PWM converter. The steady state and transient responses for wind velocity changes are simulated using Matlab Simulink. This paper verifies the fundamental performance of the system using a boost converter by discussing the simulation results of both systems. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(4): 37–54, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20902
The Halide Binding Behavior of 2‐Carbamoyl‐7‐ureido‐1H‐indoles: Conformational Aspects
Authors: Makuc Damjan , Triyanti  , Albrecht Markus , Plavec Janez , Rissanen Kari , Valkonen Arto , Schalley Christoph A. 
Published: August 2009

AbstractIndole‐based anion receptors with an carboxamide unit in 2‐ and an urea in 7‐position were prepared and found to bind halides (as well as acetate and nitrate) in chloroform solutions at room temperature. Investigations of the binding behaviour show that the receptor is selective for chloride. Surprisingly, the truncated receptor 3 without the 2‐carbamoyl substituent shows the highest affinity for Cl–. Thorough 1H, 13C and 15N NMR investigations indicate different binding modes for acetate, nitrate and halides to the receptor 2. The observation of a major conformational change of this receptor during the binding of the halide ions leads to an understanding of the relative binding affinities of 3 > 4 > 2 for chloride. The results of the NMR study are supported by ab initio calculations. In addition, ESI FTICR MS competition experiments of the indole 2 and the quinoline 1 reveal the “self‐aggregation” of the receptors and show that halides have a higher affinity to 2 than to 1.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Optimisation and validation of a new CE method for the determination of lansoprazole enantiomers in pharmaceuticals
Authors: Berzas Nevado Juon José , Castañeda Peñalvo Gregorio , Jiménez Sánchez Juan Carlos , Mochón Manuel Callejón , Rodríguez Dorado Rosa María , Villar Navarro Mercedes 
Published: August 2009

AbstractAn analytical method based on CZE to determine lansoprazole enantiomers in pharmaceuticals was developed. The primary factors affecting its separation efficiency, which include chiral selector, pH, buffer concentration, capillary temperature and injection time, were optimised. The best results were obtained by using a background electrolyte consisting of 50 mM phosphate adjusted to pH 2.2, 12 mM β‐CD and 5 mM sodium sulphite, in combination with hydrodynamic injection and a 15 kV separation voltage. Detection limits were calculated from baseline noise and found to be 0.64 mg L−1 for the R enantiomer and 0.72 mg L−1 for the S enantiomer. The proposed method was used to analyse three different pharmaceutical preparations with recoveries of 91–102% of the label content.
Box–Behnken design for the optimization of an enantioselective method for the simultaneous analysis of propranolol and 4‐hydroxypropranolol by CE
Authors: Borges Keyller Bastos , Pupo Mônica Tallarico , de Freitas Luis Alexandre Pedro , Bonato Pierina Sueli 
Published: August 2009

AbstractAn experimental design optimization (Box–Behnken design, BBD) was used to develop a CE method for the simultaneous resolution of propranolol (Prop) and 4‐hydroxypropranolol enantiomers and acetaminophen (internal standard). The method was optimized using an uncoated fused silica capillary, carboxymethyl‐β‐cyclodextrin (CM‐β‐CD) as chiral selector and triethylamine/phosphoric acid buffer in alkaline conditions. A BBD for four factors was selected to observe the effects of buffer electrolyte concentration, pH, CM‐β‐CD concentration and voltage on separation responses. Each factor was studied at three levels: high, central and low, and three center points were added. The buffer electrolyte concentration ranged from 25 to 75 mM, the pH ranged from 8 to 9, the CM‐β‐CD concentration ranged from 3.5 to 4.5% w/v, and the applied run voltage ranged from 14 to 20 kV. The responses evaluated were resolution and migration time for the last peak. The obtained responses were processed by Minitab®to evaluate the significance of the effects and to find the optimum analysis conditions. The best results were obtained using 4% w/v CM‐β‐CD in 25 mM triethylamine/H3PO4buffer at pH 9 as running electrolyte and 17 kV of voltage. Resolution values of 1.98 and 1.95 were obtained for Prop and 4‐hydroxypropranolol enantiomers, respectively. The total analysis time was around of 15 min. The BBD showed to be an adequate design for the development of a CE method, resulting in a rapid and efficient optimization of the pH and concentration of the buffer, cyclodextrin concentration and applied voltage.
Combined use of chiral ionic liquid and CD for MEKC: Part II. Determination of binding constants
Authors: Wang Bin , He Jun , Bianchi Victoria , Shamsi Shahab A. 
Published: August 2009

AbstractA competitive inhibition mechanism is proposed to investigate the interactions among 2,3,6‐tri‐O‐methyl‐β‐CD (TM‐β‐CD), cationic ionic liquid type surfactants, N‐undecenoxy‐carbonyl‐L‐leucinol bromide (L‐UCLB) and profens using affinity CE. The apparent binding constant of TM‐β‐CD to L‐UCLB was estimated by nonlinear and linear plotting methods. The binding constants of one representative profen (e.g. fenoprofen) to TM‐β‐CD and L‐UCLB were estimated by a secondary plotting approach. The R‐ and S‐fenoprofens have different binding constant values, resulting in the enantioseparation due to the synergistic effect of the two chiral selectors, TM‐β‐CD and L‐UCLB.
Full‐scale dynamic response of an RC building under weak seismic motions using earthquake recordings, ambient vibrations and modelling
Authors: Michel Clotaire , Guéguen Philippe , El Arem Saber , Mazars Jacky , Kotronis Panagiotis 
Published: August 2009

AbstractIn countries with a moderate seismic hazard, the classical methods developed for strong motion prone countries to estimate the seismic behaviour and subsequent vulnerability of existing buildings are often inadequate and not financially realistic. The main goals of this paper are to show how the modal analysis can contribute to the understanding of the seismic building response and the good relevancy of a modal model based on ambient vibrations for estimating the structural deformation under weak earthquakes. We describe the application of an enhanced modal analysis technique (frequency domain decomposition) to process ambient vibration recordings taken at the Grenoble City Hall building (France). The frequencies of ambient vibrations are compared with those of weak earthquakes recorded by the French permanent accelerometric network (RAP) that was installed to monitor the building. The frequency variations of the building under weak earthquakes are shown to be less (∼2%) and therefore ambient vibration frequencies are relevant over the elastic domain of the building. The modal parameters extracted from ambient vibrations are then used to determine the 1D lumped‐mass model in order to reproduce the inter‐storey drift under weak earthquakes and to fix a 3D numerical model that could be used for strong earthquakes. The correlation coefficients between data and synthetic motion are close to 80 and 90% in horizontal directions, for the 1D and 3D modelling, respectively. Copyright © 2009 John Wiley & Sons, Ltd.
Flow of a third grade fluid due to an accelerated disk
Authors: Asghar S. , Hanif Khalid , Hayat T. 
Published: August 2009

AbstractThe magnetohydrodynamic (MHD) flow induced by non‐coaxial rotation of porous disk and a third grade fluid at infinity is investigated. The disk is moving with uniform acceleration and rotating with a uniform angular velocity. Numerical solution of the governing nonlinear initial and boundary value problem is obtained. The effects of physical parameters on the velocity profiles are examined in detail. The present study shows that the constant acceleration part has a greater influence than the time part of the assumed variable velocity of the disk. Copyright © 2009 John Wiley & Sons, Ltd.
A σ‐coordinate non‐hydrostatic model with embedded Boussinesq‐type‐like equations for modeling deep‐water waves
Authors: Young Chih‐Chieh , Wu Chin H. 
Published: August 2009

AbstractA σ‐coordinate non‐hydrostatic model, combined with the embedded Boussinesq‐type‐like equations, a reference velocity, and an adapted top‐layer control, is developed to study the evolution of deep‐water waves. The advantage of using the Boussinesq‐type‐like equations with the reference velocity is to provide an analytical‐based non‐hydrostatic pressure distribution at the top‐layer and to optimize wave dispersion property. The σ‐based non‐hydrostatic model naturally tackles the so‐called overshooting issue in the case of non‐linear steep waves. Efficiency and accuracy of this non‐hydrostatic model in terms of wave dispersion and nonlinearity are critically examined. Overall results show that the newly developed model using a few layers is capable of resolving the evolution of non‐linear deep‐water wave groups. Copyright © 2009 John Wiley & Sons, Ltd.
Performance of IT‐SOFC with Ce0.9Gd0.1O1.95 Functional Layer at the Interface of Ce0.9Gd0.1O1.95 Electrolyte and Ni‐Ce0.9Gd0.1O1.95 Anode
Authors: Ahn J. S. , Yoon H. , Lee K. T. , Camaratta M. A. , Wachsman E. D. 
Published: August 2009

AbstractIn this paper we present results for a high power density IT‐SOFC and a method for dispersing nanosized Ce0.9Gd0.1O1.95 (GDC) particles at the GDC electrolyte and Ni‐GDC anode interface. Dispersed nanosized particles were deposited to form an anode functional layer (AFL). Anode supports were prepared by tape casting of large micron‐sized NiO powder and sub micron‐sized GDC powder without pore former. For the cathode a La0.6Sr0.4Co0.2Fe0.8O3 – δ (LSCF)‐GDC composite was used. Without an AFL the open circuit potential (OCP) and the maximum power density were 0.677 V and 407 mW cm–2, respectively, at 650 °C using 30 sccm of hydrogen and air flow‐rate. With an AFL the OCP and the maximum power density increased to 0.796 V and 994 mW cm–2, respectively, at the same temperature. Two point probe impedance measurements revealed that the AFL fabricated by the proposed method not only increased the OCP but also reduced the electrode polarisation by 68%. The effect of gas flow‐rate is also present in this paper. When hydrogen and air flow‐rate is increased to 90 sccm, the sample with AFL obtained 1.57 W cm–2 at 650 °C.
Durability Study of SOFCs Under Cycling Current Load Conditions
Authors: Hagen A. , Hendriksen P. V. , Frandsen H. L. , Thydén K. , Barfod R. 
Published: August 2009

AbstractIn fuel cell applications, the cells must be able to withstand varying operating conditions. Anode supported solid oxide fuel cells were tested under cycling current load in order to determine the durability and possibly identify degradation mechanisms.At 750 °C and a cycling between zero and 0.75 A cm–2, the cell voltage degradation rate was similar to tests with the corresponding high constant current density. However, by analyzing the impedance spectra it was found that anode degradation was becoming more important when going from constant to cycling conditions. Running the cycling load tests at 850 °C, the cells degraded similarly as under the corresponding constant current load whereas, in some cases, cells failed mechanically after a few hundred hours. These cells did not experience severe additional degradation due to the cycling of the current density until the point of failure. The mechanical failure could be avoided if the cells were sealed to an interconnect rather than directly to an alumina test house.The degradation is discussed in the light of testing setup and conditions and cycling parameters. A mechanical analysis of the occurring problems is provided as well.
Ex situ Characterisation of Composite Nafion Membranes Containing Zirconium Hydrogen Phosphate
Authors: Rodgers M. P. , Shi Z. , Holdcroft S. 
Published: August 2009

AbstractComposite membranes were fabricated by the incorporation of zirconium phosphate (ZrP) nanoparticles into Nafion 115® membranes using the exchange method in order to delineate their effect on water retention, water permeation and proton transport. Adjusting the exchange reaction time allowed the fabrication of Nafion/ZrP membranes with ZrP content ranging from 7.8 to 25.0 wt.‐%. A decrease in dimensional stability of the composite membranes upon swelling with water, compared to unmodified Nafion, is found and is attributed to hygroscopic ZrP disrupting the hydrophobic cohesive forces in Nafion. Water content and λ values increase with increasing ZrP for low ZrP contents (<20 wt.‐%), but decrease at higher ZrP contents (>20 wt.‐%). This transition is attributed to ZrP particles increasing in size as ZrP content increases until, at contents >20 wt.‐%, they no longer fit inside the hydrophilic pores of Nafion. ZrP disrupts the proton‐conducting pathway in the membranes resulting in a lowering of proton mobility and proton conductivity. However, the permeance of water vapour through Nafion/ZrP composite membranes are found to be unaffected by ZrP.
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer
Authors: Camps Jordi , Tri Nguyen Quang , Padilla‐Nash Hesed M. , Knutsen Turid , McNeil Nicole E. , Wangsa Danny , Hummon Amanda B. , Grade Marian , Ried Thomas , Difilippantonio Michael J. 
Published: August 2009

AbstractTo evaluate the mechanisms and consequences of chromosomal aberrations in colorectal cancer (CRC), we used a combination of spectral karyotyping, array comparative genomic hybridization (aCGH), and array‐based global gene expression profiling on 31 primary carcinomas and 15 established cell lines. Importantly, aCGH showed that the genomic profiles of primary tumors are recapitulated in the cell lines. We revealed a preponderance of chromosome breakpoints at sites of copy number variants (CNVs) in the CRC cell lines, a novel mechanism of DNA breakage in cancer. The integration of gene expression and aCGH led to the identification of 157 genes localized within high‐level copy number changes whose transcriptional deregulation was significantly affected across all of the samples, thereby suggesting that these genes play a functional role in CRC. Genomic amplification at 8q24 was the most recurrent event and led to the overexpression of MYC and FAM84B. Copy number dependent gene expression resulted in deregulation of known cancer genes such as APC, FGFR2, and ERBB2. The identification of only 36 genes whose localization near a breakpoint could account for their observed deregulated expression demonstrates that the major mechanism for transcriptional deregulation in CRC is genomic copy number changes resulting from chromosomal aberrations. © 2009 Wiley‐Liss, Inc.
Characterization of a hotspot region on chromosome 12 for amplification in ring chromosomes in atypical lipomatous tumors
Authors: Trombetta Domenico , Mertens Fredrik , Lonoce Angelo , D'Addabbo Pietro , Rennstam Karin , Mandahl Nils , Storlazzi Clelia Tiziana 
Published: August 2009

AbstractRing chromosomes are cytogenetic hallmarks of genomic amplification in several bone and soft tissue tumors, in particular atypical lipomatous tumors (ALT). In ALT, the ring chromosomes invariably contain amplified material from the central part of the long arm of chromosome 12, mainly 12q12→15, but often also segments from other chromosomes are involved. Previous studies have shown that one of the recurrent amplicons in ALT, located in 12q13.3‐14.1 and harboring the candidate target genes TSPAN31 and CDK4, often has a sharp centromeric border. To characterize this breakpoint region in more detail, 12 cases of ALT with ring chromosomes were analyzed by array comparative genomic hybridization and fluorescence in situ hybridization. In the seven cases showing a sharply delineated amplicon in 12q13.3‐14.1, the breakpoint region was further investigated by real time quantitative polymerase chain reaction and Vectorette PCR. The breakpoints clustered to a 146‐kb region containing 11 genes. Whereas there was no indication that the breakpoints gave rise to fusion genes, in silico analysis revealed that the breakpoint region was enriched for repeated elements that could be important for ring chromosome formation in ALT. © 2009 Wiley‐Liss, Inc.
Genomic profiling of pediatric ALK‐positive anaplastic large cell lymphoma: A Children's Cancer and Leukaemia Group Study
Authors: Youssif Catrin , Goldenbogen Jan , Hamoudi Rifat , Carreras Joaquim , Viskaduraki Maria , Cui Yu‐xin , Bacon Chris M. , Burke G. A. Amos , Turner Suzanne D. 
Published: August 2009

AbstractAnaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) is a T‐cell malignancy in which ALK expression is a consequence of the t(2;5) or a variant translocation involving Chromosome 2. For the most part, this disease presents in the pediatric population and most, but not all, patients are successfully treated. Although the t(2;5) product nucleophosmin‐ALK has been extensively studied for its transforming properties, very little is known regarding cooperative genetic mutations that may contribute to lymphomagenesis and may predict survival outcome, specifically in a purely pediatric population. We set out to determine the frequency and positions of genomic imbalances in this relatively rare disease. We collected biopsy material from 15 UK‐resident children with ALK‐expressing ALCL. We performed array comparative genomic hybridization at a resolution of 1 MB using DNA isolated from tumor tissue. Some of the more common genomic gains were confirmed by quantitative PCR. Regions of genomic gain were far more common than losses and were most often detected on chromosomes 1–4, 5–12, 14, and 17, with Chromosome 11 being the most frequent site of genomic imbalances. Patients with 14 or fewer imbalances had a lower overall 3‐year survival (87.5–40%, P = 0.14) as did patients with gains in the regions of DDB1 or BIRC5. A range of genomic imbalances exist in ALK‐expressing ALCL of a pediatric origin, with a greater number associated with poorer overall survival. © 2009 Wiley‐Liss, Inc.
Infrared reflection spectrometry analysis as a non‐destructive method of characterizing minerals and stone materials in geoarchaeological and archaeometric applications
Authors: Ostrooumov Mikhail 
Published: August 2009

AbstractThe purpose of this paper is to show the benefits and applications of using mid and far infrared reflection spectrometry (IRS) in the analysis of archaeological materials. Infrared spectral databases do not yet exist for rocks and principal minerals. In support of IRS techniques, a catalogue and new spectral database have been created with over 500 infrared reflection spectra in mid and far ranges from more than 250 different archaeological minerals and stone materials. The reflection spectrum serves as a “fingerprint” of all these materials. This new, non‐destructive method is useful for spectrometric identification and crystal chemical characterization of many rocks and minerals commonly found in archaeological contexts. Three brief examples of IRS analysis of archaeological materials are presented as test cases. It is suggested that IRS could and should become a routine approach in geoarchaeology and archaeometry for identification and provenance studies. © 2009 Wiley Periodicals, Inc.