bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of Coral Life Forms Based on Sea Current Velocity in Kei Besar Island, Maluku, and Mare Island, North Maluku
Authors: Kesuma A , Bernawis L I , Subhan B , Muhidin  , Sangadji N M 
Published: June 2024

Abstract
Diverse life forms found on coral reefs indicate resilience to environmental change, sustaining marine biodiversity and ensuring the stability of the coastal community’s ecosystems. This study investigates the relationship between sea currents and the life forms of coral reefs in Indonesia and focuses on two primary locations: Kei Besar Island, Maluku, and Mare Island in North Maluku. Sea current data from the current real-time global forecasting and coral cover data were analysed to assess the influence of current velocities on the percentage of hard coral cover and the morphological composition of corals. The dominant bottom substrate in both locations is hard coral, with varying percentages of cover. Thirteen distinct life forms of coral were identified in both study sites, with massive and sub-massive forms being the most prevalent on Kei Besar Island (41%) having average current velocities of 0.159 m/s, and branching forms (40%) being dominant on Mare Island with average current velocities were 0.103 m/s. The massive form (CM) is strongly positively (negatively) correlated with faster (slower) currents, with a correlation coefficient of 0.81 (-0.69). On the other hand, several life form of fragile coral reefs particularly Acropora branching (ACB); Acropora sub-massive (ACS); and coral Tubipora (CTU) were found to be positively (negatively) correlated with slower (faster) currents, with a correlation coefficient of 0.55 (-0.63); 0.77 (-0.75); and 0.58 (-0.67).
Generating a monthly variability of sea surface salinity based on source tracing of salt concentration and the estimated SEBAL-evaporation
Authors: Ghazali M F , Saepuloh A , Wikantika K 
Published: June 2024

Abstract
The variation and spatial distribution of sea surface salinity (SSS) depend on the geographic condition of the water surfaces and the temporal variation of atmospheric conditions. The SSS might differ in a local coastal area compared to similar situations in global and regional oceans. The SSS values have been estimated based on spatial regression of extracted water-salt concentration as a source tracing of salt against corrected Landsat 8 satellite data during the drought season of April 2023. Here, the electrical conductivity (EC) from the Cimanuk River can be used as primary data. This result, paired with the evaporation-derived surface energy balance algorithm for land (SEBAL) algorithm, explains a monthly SSS variability after the validation using pre-defined resampled regional SSS and evaporation data. The result shows variations in estimated SSS values along with fluctuated SEBAL evaporation ranging from 1.64 to 1.62 dS/m and 1.04 to 0.41 W/m2, respectively. It describes monthly variability and their relationship in a local coastal area limited to the condition of a drought season. However, the validation shows that the root means square error (RMSE) of 1.00 from the SSS map, produced by the regression model involving band 7 of Landsat 8 and 9, has satisfied the reasonable SSS value ranges besides the best accuracy.
Application of Geoid and Mean Dynamic Topography Models as an Alternative to the Mean Sea Level Approach in Determining Vertical Datum (Case Study: Java Island and Surrounding)
Authors: Sarsito D A , Syahrullah M , Bramanto B , Andreas H , Pradipta D 
Published: June 2024

Abstract
Indonesia’s archipelagic territory provides constraints for determining a seamless vertical datum throughout the region. The main constraint is how to connect the vertical datum between islands separated by sea. To define the physical height system of land areas, it usually refers to the Mean Sea Level (MSL), which has different values in each area, and the ideal MSL information is not yet available throughout regions with a minimum data duration of one cycle of 18.6 years. To overcome this constraint, in this research, another alternative method is used: applying a vertical datum that refers to a physical geoid reference surface, namely Mean Dynamic Topography (MDT) using Altimetry satellite data. The study area is Java Island and its surroundings, using vertical information from Geodetic Control Point stations, which also function as Tidal stations in the Indonesian Geospatial Reference System network. The range of MDT deviation values obtained from the Satellite Altimetry with Geodetic Ground Control data is ± 2 meters, which is a good value for coastal areas facing the open sea. This shows that the application of the geoid and MDT models can be used as an alternative, seamless MSL approach in the Java Island region and its surroundings.
The relationship between urbanization, energy consumption, economic growth, and carbon dioxide emissions in middle eastern countries: Saudi Arabia, Jordan and Egypt
Authors: Aldegheishem Abdulaziz 
Published: June 2024

Abstract
The Middle East region is a strategic driver of the global economy. However, ensuring environmental sustainability in the context of rapid urban and economic changes remains a major challenge for most Middle Eastern countries. Although researchers have widely examined factors affecting carbon dioxide emissions (CO2), little attention has been paid to the Middle Eastern countries. This study uses an ARDL model to examine the nexus between urbanization, energy consumption, economic growth, and CO2 emissions for three Middle Eastern countries, (Saudi Arabia, Egypt and Jordan) based on panel data for the period from 1990 to 2023. Findings reveal that urbanization has had no significant impact on CO2 emissions in Egypt; this is not in line with the findings for Saudi Arabia and Jordan, where urbanization has reduced CO2 emissions in the long- and short-run, indicating that urban policies are well matched with environmental goals in both countries. However, empirical results indicate that energy consumption has had a positive effect on CO2 emissions in the long- and short-run in all three countries and economic growth has also had a positive impact on CO2 emissions. The fact that economic growth has been unable to mitigate CO2 emissions indicates a mismatch between economic policies and environmental goals. This article suggests a series of valuable insights for policymakers to reduce CO2 emissions.
Practical considerations for high-fidelity wavefront shaping experiments
Authors: Mastiani Bahareh , Cox Daniël W S , Vellekoop Ivo M 
Published: June 2024

Abstract
Wavefront shaping (WFS) is a technique for directing light through turbid media. The theoretical aspects of WFS are well understood, and under near-ideal experimental conditions, accurate predictions for the expected signal enhancement can be given. In practice, however, there are many experimental factors that negatively affect the outcome of the experiment. Here, we present a comprehensive overview of these experimental factors, including the effect of sample scattering properties, noise, and response of the spatial light modulator. We present simple means to identify experimental imperfections and to minimize their negative effect on the outcome of the experiment. This paper is accompanied by Python code for automatically quantifying experimental problems using the OpenWFS framework for running and simulating WFS experiments.
Classification of single extracellular vesicles in a double nanohole optical tweezer for cancer detection
Authors: Peters Matthew , Halvaei Sina , Zhao Tianyu , Yang-Schulz Annie , Williams Karla C , Gordon Reuven 
Published: June 2024

Abstract
A major challenge in cancer prognostics is finding early biomarkers that can accurately identify cancer. Circulating tumor cells are rare and circulating tumor DNA can not provide information about the originating cell. Extracellular vesicles (EVs) contain cell specific information, are abundant in fluids, and have unique properties between cancerous and non-cancerous. Fluorescence measurements have limitations from intrinsic fluorescent background signals, photobleaching, non-specific labelling, and EV structural modifications. Here, we demonstrate a label-free approach to classification of 3 different EVs, derived from non-malignant, non-invasive cancerous, and invasive cancerous cell lines. Using double nanohole optical tweezers, the scattering from single trapped EVs is measured, and using a 1D convolutional neural network, we are able to classify the time series optical signal into its respective EV class with greater than 90% accuracy.
Sparse autoregressive neural networks for classical spin systems
Authors: Biazzo Indaco , Wu Dian , Carleo Giuseppe 
Published: June 2024

Abstract
Efficient sampling and approximation of Boltzmann distributions involving large sets of binary variables, or spins, are pivotal in diverse scientific fields even beyond physics. Recent advances in generative neural networks have significantly impacted this domain. However, these neural networks are often treated as black boxes, with architectures primarily influenced by data-driven problems in computational science. Addressing this gap, we introduce a novel autoregressive neural network architecture named TwoBo, specifically designed for sparse two-body interacting spin systems. We directly incorporate the Boltzmann distribution into its architecture and parameters, resulting in enhanced convergence speed, superior free energy accuracy, and reduced trainable parameters. We perform numerical experiments on disordered, frustrated systems with more than 1000 spins on grids and random graphs, and demonstrate its advantages compared to previous autoregressive and recurrent architectures. Our findings validate a physically informed approach and suggest potential extensions to multivalued variables and many-body interaction systems, paving the way for broader applications in scientific research.
Phase-space analysis of a two-section InP laser as an all-optical spiking neuron: dependency on control and design parameters
Authors: Puts Lukas , Lenstra Daan , Williams Kevin , Yao Weiming 
Published: June 2024

Abstract
Using a rate-equation model we numerically evaluate the carrier concentration and photon number in an integrated two-section semiconductor laser, and analyse its dynamics in three-dimensional phase space. The simulation comprises compact model descriptions extracted from a commercially-available generic InP technology platform, allowing us to model an applied reverse-bias voltage to the saturable absorber. We use the model to study the influence of the injected gain current, reverse-bias voltage, and cavity mirror reflectivity on the excitable operation state, which is the operation mode desired for the laser to act as an all-optical integrated neuron. We show in phase-space that our model is capable of demonstrating four different operation modes, i.e. cw, self-pulsating and an on-set and excitable mode under optical pulse injection. In addition, we show that lowering the reflectivity of one of the cavity mirrors greatly enhances the control parameter space for excitable operation, enabling more relaxed operation parameter control and lower power consumption of an integrated two-section laser neuron.
The visual cortex in the blind but not the auditory cortex in the deaf becomes multiple-demand regions
Authors: Duymuş Hasan , Verma Mohini , Güçlütürk Yasemin , Öztürk Mesut , Varol Ayşe B , Kurt Şehmus , Gezici Tamer , Akgür Berhan F , Giray İrem , Öksüz Elif E , Farooqui Ausaf A 
Published: June 2024

Abstract
The fate of deprived sensory cortices (visual regions in the blind and auditory regions in the deaf) exemplifies the extent to which experience can change brain regions. These regions are frequently seen to activate during tasks involving other sensory modalities, leading many authors to infer that these regions have started to process sensory information of other modalities. However, such observations can also imply that these regions are now activating in response to any task event, regardless of the sensory modality. Activating in response to task events, irrespective of the sensory modality involved, is a feature of the multiple-demands (MD) network. This is a set of regions within the frontal and parietal cortices that activate in response to any kind of control demand. Thus, demands as diverse as attention, perceptual difficulty, rule-switching, updating working memory, inhibiting responses, decision-making and difficult arithmetic all activate the same set of regions that are thought to instantiate domain-general cognitive control and underpin fluid intelligence.
We investigated whether deprived sensory cortices, or foci within them, become part of the MD network. We tested whether the same foci within the visual regions of the blind and auditory regions of the deaf activated in response to different control demands.
We found that control demands related to updating auditory working memory, difficult tactile decisions, time-duration judgments and sensorimotor speed all activated the entire bilateral occipital regions in the blind but not in the sighted. These occipital regions in the blind were the only regions outside the canonical frontoparietal MD regions to show such activation in response to multiple control demands. Furthermore, compared with the sighted, these occipital regions in the blind had higher functional connectivity with frontoparietal MD regions. Early deaf, in contrast, did not activate their auditory regions in response to different control demands, showing that auditory regions do not become MD regions in the deaf.
We suggest that visual regions in the blind do not take a new sensory role but become part of the MD network, and this is not a response of all deprived sensory cortices but a feature unique to the visual regions.
W. E. B. Du Bois’s universal history in Black Folk Then and Now (1939)
Authors: Fertik Harriet 
Published: June 2024

Abstract
While debates about ‘Eurocentric’ versus ‘Afrocentric’ theories of history have driven previous studies of Du Bois’s writings on ancient Africa, I read his account of African antiquity in Black Folk Then and Now in the context of the moral and educational projects articulated within both Greco-Roman and African American historiography. I pay special attention to conventional ancient views of history that Diodorus expresses in his Bibliotheke, which treats history as a source of morally instructive examples and ‘universal history’ as especially educational because it synthesizes different historical narratives: these concepts of history were broadly influential into the nineteenth century, including among African American writers. An ancient model of universal history allows Du Bois to tell the story of a distinct human community and nevertheless insist on the unity of peoples, a principle which is central to his philosophy of race and of human history writ large.
Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme
Authors: Danese Silvio , Dignass Axel , Matsuoka Katsuyoshi , Ferrante Marc , Long Millie , Redondo Isabel , Moses Richard , Maier Sebastian , Hunter Gibble Theresa , Morris Nathan , Milch Catherine , Abreu Maria T 
Published: June 2024

Abstract

Background and Aims
Ulcerative colitis [UC], a chronic inflammatory bowel disease, may manifest with symptoms of increased stool frequency [SF], rectal bleeding [RB], bowel urgency [BU], abdominal pain [AP], and fatigue. Mirikizumab, an anti-IL-23p19 antibody, demonstrated efficacy and safety in patients with moderately to severely active UC in the LUCENT Phase 3 trials. We evaluated mirikizumab’s efficacy in achieving symptom control and time to symptom improvement during induction, maintenance of sustained symptom control, 'comprehensive symptom control', defined according to a combination of individual patient-reported outcomes, and prognostic baseline indicators of early symptomatic remission at Week 4.

Methods
The results of LUCENT-1/-2 have previously been reported. Treatment differences for symptomatic endpoints were compared over 52 weeks versus placebo [PBO] and comprehensive symptomatic endpoints at 12 and 52 weeks of continuous treatment. Subgroup analyses were conducted for prior biologic or tofacitinib treatment failure. Prognostic analyses were run using regression analysis.

Results
By Week [W] 2, mirikizumab-treated patients achieved greater reductions in SF, RB, BU, and fatigue versus PBO. At W4, there was a higher rate of AP improvement. At W12, a greater proportion of mirikizumab-treated patients achieved symptomatic remission, RB remission, SF remission, and BU remission/clinically meaningful improvement. Mirikizumab-treated patients sustained symptom control versus placebo patients in maintenance until W52. This treatment effect was shown in patients regardless of prior biologic or tofacitinib failure. Additionally, mirikizumab achieved comprehensive symptom control versus PBO at W12 and W52.

Conclusions
Mirikizumab demonstrated efficacy in achieving and sustaining symptom control and comprehensive symptom control over 52 weeks [NCT03518086; NCT03524092].
Genetic drift drives faster-Z evolution in the salmon louse Lepeophtheirus salmonis
Authors: Mongue Andrew J , Baird Robert B 
Published: June 2024

Abstract
How sex chromosomes evolve compared to autosomes remains an unresolved question in population genetics. Most studies focus on only a handful of taxa, resulting in uncertainty over whether observed patterns reflect general processes or idiosyncrasies in particular clades. For example, in female heterogametic (ZW) systems, bird Z chromosomes tend to evolve quickly but not adaptively, while in Lepidopterans they evolve adaptively, but not always quickly. To understand how these observations fit into broader evolutionary patterns, we explore Z chromosome evolution outside of these two well-studied clades. We utilize a publicly available genome, gene expression, population, and outgroup data in the salmon louse Lepeophtheirus salmonis, an important agricultural pest copepod. We find that the Z chromosome is faster evolving than autosomes, but that this effect is driven by increased drift rather than adaptive evolution. Due to high rates of female reproductive failure, the Z chromosome exhibits a slightly lower effective population size than the autosomes which is nonetheless to decrease efficiency of hemizygous selection acting on the Z. These results highlight the usefulness of organismal life history in calibrating population genetic expectations and demonstrate the value of the ever-expanding wealth of publicly available data to help resolve outstanding evolutionary questions.
Re-energizing health literacy in Wales: a testbed for health, education and prosperity for all
Authors: Marchant Emily 
Published: June 2024

Abstract
A growing body of evidence demonstrates the importance of enhancing health literacy for improved health outcomes, self-reported health, lower health services use and disease prevention. Importantly, improving health literacy has great potential to reduce health inequities and inequalities. The World Health Organization (WHO) has identified health literacy as a global priority, viewing it as a right and a fundamental competency necessary to function within modern society. Building health literacy foundations should begin in early childhood, including focus within educational frameworks and school curricula. The WHO advocate for governments to embed it as an explicit goal. In response, it has received significant international policy and strategy focus, in addition to the development of country-level action plans. In Wales, UK, it was identified as a priority in 2010, but despite wider developments spanning health and social care, well-being, economy and education policy, growth in health literacy has stalled since. Optimizing health literacy would act as an indirect enabler to a range of Welsh policies and strategies. A promising avenue for strengthening the health literacy of current and future generations is through ongoing significant national education reforms and the introduction of the new Curriculum for Wales. One of four overarching purposes of this curriculum is healthy, confident individuals, and health and well-being constitutes one of six statutory curriculum areas. Tracking the impact of this on children and young people’s health literacy offers opportunities for Wales to model and gain traction as a national-scale health literacy policy testbed. This requires re-energizing health literacy as a national priority.
Understanding medication recycling practices in Canadian hospitals
Authors: Zou Brenda , Sung Sophia , Drummond Isla , Tang Linda , Tejani Aaron M 
Published: June 2024

Abstract

Background
Medication recycling within hospitals has proven financial and possible environmental benefits according to local evaluations done in British Columbia. Despite this, the extent of medication recycling in Canadian hospitals remains unclear in the literature.

Objective(s)
To determine if Canadian hospitals recycle medications, provide an estimate of how much medication is recycled by dosage form, and identify medication recycling barriers through the distribution of a cross-sectional survey.

Methods
A nine-question survey was distributed to 171 hospital pharmacy departments across Canada that consented to complete the survey. The survey identified whether sites recycled unused medications, an estimate of how much is recycled based on dosage form, and barriers to recycling.

Key findings
Of 62 respondents, the majority indicated they do have medication recycling procedures; however, the frequency of recycling is suboptimal (30–50% of medications are not recycled), and not all medication types are always recycled. Individually packaged oral tablets were most often recycled, and oral liquid medications were least often recycled. Many multi-dose medications were not tamper-proofed. Most respondents selected “sanitization/infection control” and “resource constraint” as reasons for not recycling all medications.

Conclusions
Among respondents, the proportion and type of unused medicines that are recycled varied. For sites that did not respond, this might suggest that medication recycling is not a priority. This could represent a missed opportunity to standardize practices and increase medication recycling in hospitals, both of which could represent a meaningful step towards responsible use of medications and reduction of negative impacts on human health and the environment.