bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elucidating the Crystallization‐Caused Phosphorescence Quenching Mechanism to Achieve Efficient Photoactivated Persistent Luminescence for High‐Quality Light Printing
Authors: Zhang Qingqing , Hu Pengtao , Han Chenyang , Mao Zhu , Chen Ruitai , Liang Zhiling , Cai Wei , Wang Leyu , Yang Zhan , Zheng Chunxiong , Liu Cong , Shi Guang , Xu Bingjia 
Published: April 2024

AbstractThe development of polymer‐based luminescent materials with efficient photoactivated ultralong organic phosphorescence (UOP) is of great importance but very challenging. Herein, a new class of organic phosphorescent luminogens is constructed by attaching phenyl rings and/or ethyl benzoates to the nitrogen atoms of a planar aromatic heterocycle pyrrolodiindole (PDI). The compounds show a significant elevation in phosphorescence emission capability after incorporating the ester group(s). However, they cannot produce room‐temperature phosphorescence in the crystalline state. These observations are identified to be associated with the formation of dimers and excimers and the motions of substituents within the molecules. In this context, the PDI derivatives are doped into epoxy polymers with compact and permanent 3D covalent networks. The resulting polymer films show reversible photoactivated UOP under ambient conditions, with quantum yields and lifetimes of up to 24.4% and 2.03 s, respectively, thereby enabling high‐quality and erasable light printing and multi‐level anti‐counterfeiting applications. In addition, they also exhibit excellent water and chemical resistance. This work is conducive to understanding the generation and decay mechanisms of the triplet excitons of organic luminophores with planar aromatic heterocycles in the crystalline state and provides a direction for the development of high‐performance photoactivated UOP materials.
Quantitative and qualitative analysis of stability for 16 serum immunoregulators over 50 freeze–thaw cycles
Authors: Chowdhury R. N. , Armato A. , Culver E. , Shteynman L. , Kurien C. , Cradin B. , Margolin F. , Nguyen T. , Cardona C. , Kabir N. , Garruto R. M. , Lum J. K. , Wander K. 
Published: April 2024

AbstractObjectivesTo evaluate the reliability of data from the assay of bio‐archived specimens, a 50‐freeze–thaw‐cycle (FTC) degradation study of fresh sera was conducted to test the stability of 16 immunoregulators.MethodsTwenty de‐identified serum specimens were obtained from volunteers at United Health Services‐Wilson Memorial Hospital. Specimens were stored at −20°C and underwent daily 1 h thawing and subsequent freezing for each FTC over 50 consecutive days. Immunoregulator concentrations were assessed via enzyme‐linked immunosorbent assay (ELISA) in participant samples at 2 FTC (baseline), 25 FTC, and 50 FTC. Specific immunoregulators observed in the study were C‐reactive protein (CRP), interleukin (IL)‐1α, 4, 6, 8, 10, monocyte chemoattractant protein‐1 (MCP‐1, CCL2), monocyte chemoattractant protein‐2 (MCP‐2, CCL8), eotaxin‐1, thymus‐and‐activation‐regulated chemokine (TARC, CCL17), regulated on activation normal T‐cell expressed and secreted (RANTES, CCL5), growth‐regulated oncogene‐alpha (GRO‐α, CXCL1), small inducible cytokine A1 (I‐309, CCL1), interferon‐gamma (IFN‐γ), interferon‐gamma inducible protein‐10 (IP‐10, CXCL10), and tumor necrosis factor‐alpha (TNF‐α).ResultsQuantitative stability of serum immunoregulators: Serum CRP, IL‐8, IL‐10, IFN‐γ, IP‐10, and eotaxin‐1 levels appear to be statistically equivalent from baseline to 50 FTC (p ≤ .05). Retention of patterns in serum immunoregulators: patterns across FTC were retained for TARC (age) and CRP, IFN‐γ, and MCP‐2 (sex).ConclusionsWhile the effect of multiple FTC on serum immunoregulator levels may not replicate prolonged freezer storage, the results of this study provide valuable information on the robustness of immunoregulators for research using bio‐archived sera.
An Efficient Synthesis of α‐Sulfonamide Phosphonates through Metal‐Free Three‐Component Reaction
Authors: Ramani Arti , Bhavyesh Desai , Kanta Koppolu Mani , Chinna Ashalu Kashamalla , Begari Eeshwaraiah , Naveen Togati 
Published: April 2024

AbstractA metal‐free three‐component reaction for the direct synthesis of α‐sulfonamide phosphonates involving sulfonamide derivatives, benzaldehyde derivatives, and diethyl phosphite, has been achieved with high yields using ethanol as a green solvent. This efficient method reduces reaction time and minimizes the use of excess reagents. Hitherto, no reports have been found in the literature for the direct synthesis of α‐sulfonamide phosphonates from the readily available aldehydes, diethyl phosphite, and sulfonamides, emphasizing the novelty and significance of this work.
Comparing short‐axis versus long‐axis ultrasound‐guided techniques for internal jugular vein cannulation: A meta‐analysis of clinical outcomes and safety
Authors: AlGhamdi Faisal , AlJoaib Nasser , Aldawood Ali , AlGhamdi Mohammed , AlMulhim Abdullah 
Published: April 2024

AbstractIntroductionCentral venous access plays a crucial role in various clinical settings, and ultrasound guidance has become increasingly popular for improving its safety and success rates. The aim of this meta‐analysis was to compare the short‐axis (SAX) and long‐axis (LAX) ultrasound‐guided techniques for internal jugular vein (IJV) cannulation in terms of first needle pass success rate, number of cannulation attempts, access time, guidewire insertion time, posterior IJV wall puncture, arterial puncture, haematoma and catheter‐related bloodstream infection.MethodsA comprehensive literature search was conducted, and randomised controlled trials (RCTs) comparing SAX and LAX techniques for IJV cannulation on adults were included.ResultsA total of 11 RCTs involving 1183 patients were included in the meta‐analysis. The SAX technique demonstrated a significantly greater first needle pass success rate and faster IJV access time compared to the LAX technique. However, more posterior IJV wall puncture was significantly associated with the SAX technique. There was no significant difference between the two techniques in terms of number of cannulation attempts, guidewire insertion time, arterial puncture, haematoma and catheter‐related bloodstream infection.ConclusionThis meta‐analysis suggests that the SAX technique may have advantages over the LAX technique in terms of first needle pass success rate and potentially reducing cannulation attempts and access time. However, the occurrence of posterior IJV wall puncture raises concerns. The decision on the choice of technique should be based on individual patient factors and operator proficiency.
Data‐driven decomposition and staging of flortaucipir uptake in Alzheimer's disease
Authors: Earnest Tom , Bani Abdalla , Ha Sung Min , Hobbs Diana A. , Kothapalli Deydeep , Yang Braden , Lee John J. , Benzinger Tammie L. S. , Gordon Brian A. , Sotiras Aristeidis ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: April 2024

AbstractINTRODUCTIONPrevious approaches pursuing in vivo staging of tau pathology in Alzheimer's disease (AD) have typically relied on neuropathologically defined criteria. In using predefined systems, these studies may miss spatial deposition patterns which are informative of disease progression.METHODSWe selected discovery (n = 418) and replication (n = 132) cohorts with flortaucipir imaging. Non‐negative matrix factorization (NMF) was applied to learn tau covariance patterns and develop a tau staging system. Flortaucipir components were also validated by comparison with amyloid burden, gray matter loss, and the expression of AD‐related genes.RESULTSWe found eight flortaucipir covariance patterns which were reproducible and overlapped with relevant gene expression maps. Tau stages were associated with AD severity as indexed by dementia status and neuropsychological performance. Comparisons of flortaucipir uptake with amyloid and atrophy also supported our model of tau progression.DISCUSSIONData‐driven decomposition of flortaucipir uptake provides a novel framework for tau staging which complements existing systems.Highlights
NMF reveals patterns of tau deposition in AD.
Data‐driven staging of flortaucipir tracks AD severity.
Learned flortaucipir patterns overlap with AD‐related gene expression.
Microwave Assisted Fast Synthesis of a Donor‐Acceptor COF Towards Photooxidative Amidation Catalysis
Authors: Dey Anupam , Chakraborty Samiran , Singh Ashish , Rahimi Faruk Ahamed , Biswas Sandip , Mandal Tamagna , Maji Tapas Kumar 
Published: April 2024

AbstractThe synthesis of covalent organic frameworks (COFs) at bulk scale require robust, straightforward, and cost‐effective techniques. However, the traditional solvothermal synthetic methods of COFs suffer low scalability as well as requirement of sensitive reaction environment and multiday reaction time (2–10 days) which greatly restricts their practical application. Here, we report microwave assisted rapid and optimized synthesis of a donor‐acceptor (D−A) based highly crystalline COF, TzPm‐COF in second (10 sec) to minute (10 min) time scale. With increasing the reaction time from seconds to minutes crystallinity, porosity and morphological changes are observed for TzPm‐COF. Owing to visible range light absorption, suitable band alignment, and low exciton binding energy (Eb=64.6 meV), TzPm‐COF can efficaciously produce superoxide radical anion (O2.−) after activating molecular oxygen (O2) which eventually drives aerobic photooxidative amidation reaction with high recyclability. This photocatalytic approach works well with a variety of substituted aromatic aldehydes having electron‐withdrawing or donating groups and cyclic, acyclic, primary or secondary amines with moderate to high yield. Furthermore, catalytic mechanism was established by monitoring the real‐time reaction progress through in situ diffuse reflectance infrared Fourier transform spectroscopic (DRIFTS) study.
Kinetic Resolution Polymerization Enabled Chemical Synthesis of Perfectly Isotactic Polythioesters
Authors: Li Kun , Cheng Jing‐Liang , Wang Meng‐Yuan , Xiong Wei , Huang Hao‐Yi , Feng Liang‐Wen , Cai Zhongzheng , Zhu Jian‐Bo 
Published: April 2024

AbstractIsotactic polythioesters (PTEs) that are thioester analogs to natural polyhydroxyalkanoates (PHAs) have attracted growing attention due to their distinct properties. However, the development of chemically synthetic methods for preparing isotactic PTEs has long been an intricate endeavour. Herein, we report the successful synthesis of perfectly isotactic PTEs via stereocontrolled ring‐opening polymerization. This binaphthalene‐salen aluminium (SalBinam‐Al) catalyst promoted a robust polymerization of rac‐α‐substituted‐β‐propiothiolactones (rac‐BTL and rac‐PTL) with highly kinetic resolution, affording perfectly isotactic P(BTL) and P(PTL) with Mn up to 276 kDa. Impressively, the isotactic P(BTL) formed a supramolecular stereocomplex with improved thermal property (Tm=204 °C). Ultimately, this kinetic resolution polymerization enabled the facile isolation of enantiopure (S)‐BTL, which could efficiently convert to an important pharmaceutical building block (S)‐2‐benzyl‐3‐mercapto‐propanoic acid. Isotactic P(PTL) served as a tough and ductile material comparable to the commercialized polyolefins. This synthetic system allowed to access of isotactic PTEs, establishing a powerful platform for the discovery of sustainable plastics.
Enable the Domino‐Like Structural Recovering in Bismuth Anode to Achieve Fast and Durable Na/K Storages
Authors: Long Hongli , Wang Jing , Zhao Shengyu , Zou Bobo , Yan Liuming , Huang Qiuan , Zhao Yufeng 
Published: April 2024

AbstractAlloying‐type anodes show capacity and density advantages for sodium/potassium‐ion batteries (SIBs/PIBs), but they encounter serious structural degradation upon cycling, which cannot be resolved through conventional nanostructuring techniques. Herein, we present an in‐depth study to reveal the intrinsic reason for the pulverization of bismuth (Bi) materials upon (de)alloying, and report a novel particle‐in‐bulk architecture with Bi nanospheres inlaid in the bulk carbon (BiNC) to achieve durable Na/K storage. We simulate the volume‐expansion‐resistant mechanism of Bi during the (de)alloying reaction, and unveil that the irreversible phase transition upon (de)alloying underlies the fundamental origin for the structural degradation of Bi anode, while a proper compressive stress (~10 %) raised by the bulk carbon can trigger a “domino‐like” Bi crystal recovering. Consequently, the as obtained BiNC exhibits a record high volumetric capacity (823.1 mAh cm−3 for SIBs, 848.1 mAh cm−3 for PIBs) and initial coulombic efficiency (95.3 % for SIBs, 96.4 % for PIBs), and unprecedented cycling stability (15000 cycles for SIBs with only 0.0015 % degradation per cycle), outperforming the state‐of‐the‐art literature. This work provides new insights on the undesirable structural evolution, and proposes basic guidelines for design of the anti‐degradation structure for alloy‐type electrode materials.
Preparation and properties of phenolic foam modified with boric acid and organosiloxane by supercritical CO2 technology
Authors: Wang Xinlong , Yuan Lailai , Zhao Hui , Ou Ye , Gao Tong , Xu Tingting , Chen Lixin 
Published: April 2024

AbstractIn this study, a silica boron modified phenolic resin foam (SiBPF) is prepared in a reactor under specific pressure and temperature and using supercritical CO2 (scCO2) as a physical foaming agent, to improve phenolic foam (PF) brittle and friable properties and avoid environmental pollution caused by conventional physical foaming. To determine the partially curing degree for foaming, the influence of partially curing time at partially curing degrees between 39.88% and 53.17% was studied. Further, through an orthogonal experimental method, the optimized foaming process parameters—partially curing time of 6 h, adsorption time of 9 h, foaming pressure of 1 MPa, and foaming temperature of 130°C—were determined. The SiBPF, thus prepared under the optimized conditions, exhibited a density of 0.2356 g/cm3, an average cell size of 86.66 μm, and a cell density of 7.10 × 106 cells/cm3. Its compressive strength was found to be 7.28 MPa, with a specific compressive strength of 30.90 MPa/g·cm−3. At 800°C, the carbon residue rate, thermal decomposition temperature T5%, and Tmax reached 77.61%, 355.21, and 702.70°C, respectively. The thermal conductivity of SiBPF was measured to be 0.0644 W/mK, with the rear temperature stabilizing at 60°C on a hot platform of 100°C.
Stability analysis of stochastic nonlinear switched systems with time‐delay and its application
Authors: Yao Liqiang , Yin Yanna , Feng Likang 
Published: April 2024

AbstractThis paper studies the stability of stochastic nonlinear time‐delay systems with arbitrary switching and its application. A novel Krasovskii‐type stability theorem is introduced for stochastic nonlinear systems featuring arbitrary switching and time‐delay. Unlike previous results, this stability result removes the restriction that the infinitesimal generator of Lyapunov–Krasovskii functional (i.e.,
) must be negative definite and allows
to be indefinite. As an application, the tracking control is studied for a class of stochastic switched systems with inverse dynamics and time‐delay. The assumption condition imposed on the inverse dynamic subsystem is weaker compared with most of existing findings. Finally, we illustrate the feasibility and effectiveness of proposed control strategy by two simulation examples.
Aqueous Rechargeable Manganese/Iodine Battery
Authors: Soundharrajan Vaiyapuri , Pham Duong Tung , Piao Junji , Nithiananth Subramanian , Kim Jung Ho , Kim Jaekook 
Published: April 2024

AbstractCarbon neutralization has promoted the identification of new types of energy storage devices. Aqueous iodine batteries (AIBs) with reversible iodine redox activity are considered a viable candidate for stationary energy storage units and thus have recently drawn extensive research interest. Herein, we introduce an aqueous manganese iodine battery (AMIB), utilizing sodium iodide (NaI) as a redox‐active additive in the Mn(ClO4)2 (NMC) electrolyte, activated carbon (AC) as a redox host and Mn ions as the charge carrier. Taking advantage of enhanced kinetics facilitated by I2/2I− redox activity, our suggested AMIBs can be electrochemically charged/discharged with only a 6 % loss in capacity after 2,000 cycles at a low current density of 0.3 A g−1 in an AC||AC coin cell configuration. Moreover, the AC||Zn−Mn hybrid full‐cell configuration is also established with AC and a Zn−Mn anode involving the NMC electrolyte, which retains a high energy of 185 Wh kg−1 at a specific power of 2,600 W kg−1. Overall, the AMIBs in this study preferred I2/I− conversion chemistry, yielding stable cycle stability, rate performance, and low capacity loss per cycle when compared to Manganese Ion Batteries (MIBs) which are based on Mn2+ intercalation chemistry.
A systematic review and network meta‐analysis comparing Rezūm with transurethral needle ablation and microwave thermotherapy for the management of enlarged prostate
Authors: Bhatia Ansh , Porto Joao G. , Titus Renil S. , Ila Vishal , Shah Khushi , Malpani Ankur , Lopategui Diana M. , Marcovich Robert , Herrmann Thomas R. W. , Shah Hemendra N. 
Published: April 2024

AbstractObjectivesWe aim to compare efficacy and safety of water vapour therapy (Rezūm), transurethral needle ablation (TUNA) and transurethral microwave therapy (TUMT) for treating men with moderate to severe benign prostatic hyperplasia (BPH) symptoms.MaterialsPubMed/MEDLINE, EMBASE and Cochrane Library were searched from inception to 30 July 2023, followed by reference searching and dual‐independent study selection. We analysed only randomized clinical trials. RoB‐2, NIH‐quality assessment tool and GRADE guidelines were used for quality‐of‐evidence (QoE) assessment. Relevant prospective studies without a critical risk‐of‐bias were included.ResultsAt 12 months, Rezūm showed similar efficacy to TUNA and TUMT for improvement in International Prostate Symptoms Score – Rezūm versus TUMT: 1.33 points (95% CI: −1.66 to 4.35) favouring TUMT (QoE: Moderate) and Rezūm versus TUNA: 0.07 points (95% CI: −3.64 to 3.88) favouring TUNA (QoE: Low). Rezum had similar outcomes to TUNA and TUMT for Maximum Peak‐Flow Rate (Qmax): Rezūm versus TUMT: 1.05 mL/s (95% CI: −4.88 to 2.82) favouring Rezūm (QoE: Low) and Rezūm versus TUNA: 0.37 mL/s (95% CI: −4.61 to 4.21) favouring TUNA (QoE: Low). Furthermore, post‐void residual volume (PVR) comparisons demonstrated that Rezūm was similar, or inferior to other techniques at 12 months – Rezūm versus TUMT: 11.20 mL (95% CI: −32.40 to 10.30) favouring TUMT (QoE: Low) and Rezūm versus TUNA: 24.10 mL (95% CI: 2.81 to 45.10) favouring TUNA (QoE: Low). Rezūm also had a similar surgical retreatment rate with TUMT and TUNA up to 3‐years – TUMT versus Rezūm RR: 1.21 (95% CI: 0.20 to 15.90) (QoE: Low) and TUNA versus Rezūm showed RR: 1.81 (95% CI: 0.2 to 24.60) (QoE: Low). In the first 12 months after treatment, Rezūm had a higher rate of serious adverse events (Clavien‐Dindo ≥ Grade 3) than TUMT and TUNA. TUMT versus Rezūm with RR = 0.53 (95% CI: 0.13 to 3.14) (QoE: Low) and TUNA versus Rezūm with RR = 0.38 (95% CI: 0.04 to 3.49) (QoE: Low).ConclusionsModerate to weak evidence suggests that Rezūm is not superior to TUNA and TUMT in all domains studied.
Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring‐opening polymerization and click chemistry
Authors: Porras Julian D. , Diaz Ivonne L. , Perez Leon D. 
Published: April 2024

AbstractThis study focused on synthesizing and characterizing PEGylated amphiphilic block copolymers with pendant linoleic acid (Lin) moieties as an alternative to enhance their potential in drug delivery applications. The synthesis involved a two‐step process, starting with ring‐opening polymerization of ε‐caprolactone (CL) and propargylated cyclic carbonate (MCP) to obtain PEG‐b‐P(CL‐co‐MCP) copolymers, which were subsequently modified via click chemistry. Various reaction conditions were explored to improve the yield and efficiency of the click chemistry step. The use of anisole as a solvent, N‐(3‐azidopropyl)linoleamide as a substrate, and a reaction temperature of 60°C proved to be highly efficient, achieving nearly 100% conversion at a low catalyst concentration. The resulting copolymers exhibited controlled molecular weights and low polydispersity, confirming the successful synthesis. Furthermore, click chemistry allows for the attachment of Lin moieties to the copolymer, enhancing its hydrophobic character, as deduced from their significantly lower critical micelle concentration than that of traditional PEG‐b‐PCL systems, which is indicative of enhanced stability against dilution. The modified copolymers exhibited improved thermal stability, making them suitable for applications that require high processing temperatures. Dynamic light scattering and transmission electron microscopy confirmed the formation of micellar structures with sizes below 100 nm and minimal aggregate formation. Additionally, 1H NMR spectroscopy in deuterated water revealed the presence of core‐shell micelles, which provided higher kinetic stability against dilution.
Diabetes and vascular mild cognitive impairment among Chinese ≥50 years: A cross‐sectional study with 2020 participants
Authors: Zhang Yu , Liu Wenna , Fu Chen , Liu Xuemei , Hou Xiaobing , Niu Huanmin , Li Tao , Guo Chunyan , Li Aixun , Chen Baoxin , Jin Xianglan 
Published: April 2024

AbstractBackgroundWith the decline of cognitive function in vascular cognitive impairment, the burden on the family and society will increase. Therefore, early identification of vascular mild cognitive impairment (VaMCI) is crucial. The focus of early identification of VaMCI is on the attention of risk factors. Therefore, this study aimed to investigate the relationship between diabetes and VaMCI among the Chinese, hoping to predict the risk of VaMCI by diabetes and to move the identification of vascular cognitive impairment forward.MethodsWe collected data from seven clinical centers and nine communities in China. All participants were over 50 years of age and had cognitive complaints. We collected basic information of the participants, and cognitive function was professionally assessed by the Montreal Cognitive Assessment scale. Finally, logistic regression analysis was used to analyze the correlation between each factor and VaMCI.ResultsA total of 2020 participants were included, including 1140 participants with VaMCI and 880 participants with normal cognition. In univariate logistic regression analysis, age, heavy smoking, and diabetes had a positive correlation with VaMCI. At the same time, being married, high education, and light smoking had a negative correlation with VaMCI. After correction, only diabetes (OR = 1.04, 95% CI: 1.01–1.09, p = 0.05) had a positive correlation with VaMCI, and high education (OR = 0.60, 95% CI:.45–.81, p = 0.001) had a negative correlation with VaMCI.ConclusionIn our study, we found that diabetes had a positive correlation with VaMCI, and high education had a negative correlation with VaMCI. Therefore, early identification and timely intervention of diabetes may reduce the risk of VaMCI and achieve early prevention of VaMCI.