bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renal artery stenting in patients with chronic ischemic heart disease
Authors: Trani Carlo , Tommasino Antonella , Giammarinaro Maura , Burzotta Francesco , Coroleu Santiago Federico , Rufini Vittoria , Mazzari Mario Attilio , Porto Italo , Niccoli Giampaolo , Leone Antonio Maria , Mongiardo Rocco , Gabrielli Francesca Augusta , Schiavoni Giovanni , Biamino Giancarlo , Crea Filippo 
Published: March 2010

AbstractObjectives: To investigate the role of renal stenting in selected patients with chronic ischemic heart disease and renal artery stenosis. Methods: Consecutive patients, with chronic ischemic heart disease and severe hypertension and/or impaired renal function undergoing renal stenting, were prospectively enrolled. Mid‐term (at least 2 years) follow‐up was performed to assess both changes in renal function [serum creatinine and estimated glomerular filtrate rate (eGFR)] and blood pressure (BP) control (number of required drugs) and to record the incidence of clinical major adverse events. Moreover, in the first consecutive 24 patients, out‐of‐range pressure values at 24‐hr BP monitoring and GFR at renal scintigraphy were measured at baseline and 1 month after stenting. Results: Seventy patients treated by stenting on 86 renal arteries entered the study. Procedural success rate was 99% and no major complication occurred. At 2‐year follow‐up, both mean serum creatinine (−0.1 ± 0.7 mg/dl at follow‐up compared to baseline, P = 0.6) and eGFR (+3.7 ± 23.5 ml/min/1.73m2 at follow‐up compared to baseline, P = 0.2) did not significantly change while the number of drugs required to control BP significantly decreased (2.7 ± 0.8 to 2.2 ± 0.7, P < 0.0001). In the subset of 24 patients evaluated at 1 month, GFR significantly increased (62 ± 20 ml/min to 67 ± 21 ml/min; P = 0.008) and the rate of the out‐of‐range systolic pressure values at 24‐hr monitoring significantly decreased (51–33%, P = 0.005). Elevated baseline creatinine values and the presence of global renal ischemia were identified as predictors of poor outcome at the multivariate analysis. Conclusions: In selected patients with chronic ischemic heart disease and hypertension and/or renal insufficiency, renal stenting may be performed with very low periprocedural complications and results in unchanged renal function and improved BP control. © 2010 Wiley‐Liss, Inc.
Asymmetric Synthesis of Bicyclic Diol Derivatives through Metal and Enzyme Catalysis: Application to the Formal Synthesis of Sertraline
Authors: Krumlinde Patrik , Bogár Krisztián , Bäckvall Jan‐E. 
Published: March 2010

AbstractEnzyme‐ and ruthenium‐catalyzed dynamic kinetic asymmetric transformation (DYKAT) of bicyclic diols to their diacetates was highly enantio‐ and diastereoselective to give the corresponding diacetates in high yield with high enantioselectivity (99.9 % ee). The enantiomerically pure diols are accessible by simple hydrolysis (NaOH, MeOH), but an alternative enzyme‐catalyzed ester cleavage was also used to give the trans‐diol (R,R)‐1 b in extremely high diastereomeric purity (trans/cis=99.9:0.1, >99.9 % ee). It was demonstrated that the diols can be selectively oxidized to the ketoalcohols in a ruthenium‐catalyzed Oppenauer‐type reaction. A formal enantioselective synthesis of sertraline from a simple racemic cis/trans diol 1 b was demonstrated.
Localization of MglA, an essential gliding motility protein in Myxococcus xanthus
Authors: Patryn Jacek , Allen Krisandra , Dziewanowska Katarzyna , Otto Rebecca , Hartzell Patricia L. 
Published: March 2010

AbstractMglA, a 22‐kDa protein related to monomeric GTPases, is required for the normal operation of the A (Adventurous) and S (Social) motility and for multicellular development of Myxococcus xanthus. To determine how MglA controls A‐ and S‐motility, MglA was assayed biochemically and its cellular location was determined. His‐tagged MglA hydrolyzed GTP slowly in vitro at a rate nearly identical to that of Ras showing that MglA has GTPase activity. Immunofluorescence microscopy of fixed cells from liquid showed that MglA was associated with helical track similar to the MreB spiral that spanned the length of the cell. The distribution pattern of MglA depended on the type of surface from which cells were harvested. In cells gliding on 1.5% (w/v) agar, the helical pattern gave way to punctate clusters of MglA‐Yfp at the poles and along the long axis (lateral clusters). The lateral clusters emerged near the leading pole as the cell advanced coincident with a decrease in the intensity of the MglA‐Yfp cluster at the leading pole. Newly formed lateral clusters remained fixed with regard to the substratum as the cell moved forward, similar to focal adhesion complexes described for AglZ, a protein partner of MglA. Lateral clusters did not form in cells gliding in methylcellulose, a polymer that stimulates S‐motility at low cell density; rather MglA‐Yfp was diffuse in the cytoplasm and more concentrated at the poles. The results suggest that conditions that favor S‐motility prevent the formation of lateral clusters of MglA, which are associated with A‐motility functions. © 2010 Wiley‐Liss, Inc.
Color constancy from invariant wavelength ratios. III: Chromatic adaptation theory, model and tests
Authors: Pridmore Ralph W. 
Published: March 2010

AbstractA theory of chromatic adaptation is derived from Parts I and II, and presented in terms of relative wavelength, purity, and radiant power, leading directly to a predictive model of corresponding hue, chroma, and lightness. Considering that even simple animals have effective color vision and color constancy, the aim was to develop a simple model of complete adaptation. The model is tested against well‐known data sets for corresponding colors in illuminants D65, D50, and A, and for small and large visual fields, and performs comparably to CIECAM02. Constant hue is predicted from Part I's mechanism of color constancy from invariant wavelength ratios, where constant hues shift wavelength linearly with reciprocal illuminant color temperature. Constant chroma is predicted from constant colorimetric purity. Constant lightness is predicted from chromatic adaptation of spectral sensitivity represented by power ratios of complementary colors (rather than cone responses which lack spectral sharpening). This model is the first of its type and is not formatted for ease of computation. © 2010 Wiley Periodicals, Inc. Col Res Appl, 2010
Growth and EBSD determination of Celestite SrSO4 dendrites
Authors: Qiu Z. H. , Ruan Q. F. , Zhao S. R. , Xu H. J. , Meng J. 
Published: March 2010

AbstractIn this paper, the SrSO4 dendrites were prepared by diffusion method. Electron backscattered diffraction (EBSD) technique is used to determine the crystallographic orientations of SrSO4 dendrites. It is shown that the SrSO4 dendrites grow in (001) plane, and all short main branches grow along <100>, but the long main branches grow along <110>, <130> or <140> directions. The growth morphology of SrSO4 dendrites is controlled by not only their internal structure but also external growth conditions. The internal structure of SrSO4 dendrites influences the character of the growth direction vertically <001>. The change of the ions concentration in the diffusion system leads to the evolution from <110> to <140> of the long main branches. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Effect of temperature and isomorphic atom substitution on optical absorption edge of TlInS2xSe2(1‐x) mixed crystals (0.25 ≤ x ≤ 1)
Authors: Gasanly N. M. 
Published: March 2010

AbstractThe optical properties of the TlInS2xSe2(1‐x)mixed crystals (0.25 ≤ x ≤ 1) have been investigated through the transmission and reflection measurements in the wavelength range of 400–1100 nm. The optical indirect band gap energies were determined by means of the analysis of the absorption data. It was found that the energy band gaps decrease with the increase of selenium atoms content in the TlInS2xSe2(1‐x)mixed crystals. The transmission measurements carried out in the temperature range of 10–300 K revealed that the rates of change of the indirect band gaps with temperature are γ = –9.2×10–4 eV/K, –6.1×10–4 eV/K, –4.7×10–4 eV/K and –5.6×10–4 eV/K for TlInS2, TlInS1.5Se0.5, TlInSSe and TlInS0.5Se1.5 crystals, respectively. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Structure and humidity sensing properties of SnO2 zigzag belts
Authors: Li Lijun , Yu Ke , Wu Jin , Wang Yang , Zhu Ziqiang 
Published: March 2010

AbstractA novel method was developed for synthesizing ultralong SnO2 zigzag belts with the assistance of CuO powder. The crystalline structure and morphology of SnO2 zigzag belts were characterized using x‐ray diffraction, scanning electron microscopy and transmission electron microscopy. The growth mechanism of the ultralong SnO2 zigzag belts and the catalytic behavior of the copper were discussed. The humidity sensor based on as‐synthesized product shows high sensitivity and fast response time due to unique structure of the SnO2 zigzag belts with large surface‐to‐volume ratio. It can be found that the resistance of the SnO2 materials decreases obviously with increasing relative humidity (RH) at room temperature (26 °C). The results demonstrate that these SnO2 nanostructures are potential to be used as effective and high performance humidity sensors. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Rm62, a DEAD‐box RNA helicase, complexes with DSP1 in Drosophila embryos
Authors: Lamiable O. , Rabhi M. , Peronnet F. , Locker D. , Decoville M. 
Published: March 2010

AbstractTwo main classes of proteins, Polycomb group (PcG) and Trithorax group (TrxG), play a key role in the regulation of homeotic genes. These proteins act in multimeric complexes to remodel chromatin. A third class of proteins named Enhancers of Trithorax and Polycomb (ETP) modulates the activity of TrxG and PcG, but their role remains largely unknown. We previously identified an HMGB‐like protein, DSP1 (Dorsal Switch Protein 1), which was classified as an ETP. Preliminary studies have revealed that DSP1 is involved in multimeric complexes. Here we identify a DEAD‐box RNA helicase, Rm62, as partner of DSP1 in a 250‐kDa complex. Coimmunoprecipitation assays performed on embryo extracts indicate that DSP1 and Rm62 are associated in 3‐ to 12‐h embryos. Furthermore, DSP1 and Rm62 colocalize on polytene chromosomes. Consistent with these results, a mutation in Rm62 enhances a null mutation of dsp1 and also mutations of trxG or PcG, suggesting that Rm62 has characteristics of an ETP. We show here for the first time that an RNA helicase is involved in the maintenance of homeotic genes. genesis 48:244–253, 2010. © 2010 Wiley‐Liss, Inc.
Estimation of renal function in patients with eating disorders
Authors: Fabbian Fabio , Pala Marco , Scanelli Giovanni , Manzato Emilia , Longhini Carlo , Portaluppi Francesco 
Published: March 2010

AbstractBackground:Renal function could be evaluated with different equations such as Cockcroft–Gault formula (C‐G), Mayo Clinic Quadratic (MAYO) and four MDRD variables. Clinical application of different formulae in conditions with severe energy restriction or in obese subjects is still a matter of investigation.Method:Renal function of 55 anorexia nervosa (AN) and 44 bulimia nervosa (BN) patients was evaluated with C‐G formula for creatinine clearance calculation, and glomerular filtration rate (GFR) was estimated with MAYO and MDRD equations.Results:BN group was older and had higher weight, body mass index (BMI), body surface area than AN subjects; however, their mean BMI was in the normal range. AN group had better renal function than BN one when it was evaluated with MAYO and MDRD; on the contrary, it was worse when it was calculated with C‐G. The results obtained from the three formulae were poorly correlated and Bland–Altman analysis confirmed that the results of the three formulae were not in agreement.Discussion:C‐G is inaccurate when it is applied to obese or cachectic subjects. MDRD underestimates renal function in normal‐high GFR. MAYO seems to be a good alternative to the other equations leading to correct classification of patients; therefore, it should be used to diagnose eating disorder subjects as renal insufficient. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:233–237)
Mild Synthetic Routes to High‐Surface Zinc Oxide Nanopowders
Authors: Estruga Marc , Domingo Concepción , Ayllón José A. 
Published: March 2010

AbstractZnO nanostructured powders have been prepared at low temperature and atmospheric pressure by thermal decomposition of solid precursors. Two alternative methods have been explored by using: (i) commercial zinc acetate dihydrate and (ii) a solid mixture obtained after the evaporation of a solution of zinc acetate in aqueous ammonia at 90 °C. Powder X‐ray diffraction characterization shows that in both cases crystalline ZnO was obtained after precursor treatment at 90 °C over 150 h. According to attenuated total reflection Fourier transform infrared analysis, powders obtained by both routes retain a small percentage of adsorbed acetate. Elemental analysis proves that almost 98 wt.‐% of acetate was removed during the low‐temperature treatment. Low‐temperature nitrogen adsorption‐desorption characterization shows the existence of two types of pores: intra‐aggregate mesopores and interaggregate macropores. The specific surface area reached a value of 35 m2 g–1 for materials obtained following the direct route (i) and increased to 60 m2 g–1 for powders obtained by the ammonia route (ii). TEM characterization confirms the presence of a hierarchical pore structure as a result of the formation of sub‐micrometric porous aggregates (50–200 nm) composed of nanocrystals smaller than 20 nm.
NCN‐Chelated Organoantimony(III) and Organobismuth(III) Phosphonates: Syntheses and Structures
Authors: Svoboda Tomáš , Jambor Roman , Růžička Aleš , Padělková Zdeňka , Erben Milan , Jirásko Robert , Dostál Libor 
Published: March 2010

AbstractThe reactions of the organoantimony and organobismuthoxides [LSbO]2 (1) and [LBiO]2 (2), where L = [2,6‐(Me2NCH2)2C6H3]–, with selected organophosphonic acids in a 1:4 molar ratio gave molecular organoantimony and organobismuth phosphonates LM[OP(R)(O)(OH)]2 [M = Sb, R = Et (3), Ph (4), tBu (5); M = Bi, R = tBu (8)]. Similarly, the reactions of 1 and 2 with tBuP(O)(OH)2 in a 1:2 molar ratio resulted in LM[O2P(tBu)(O)] [M = Sb (6), M = Bi (9)]. Reactions of 6 and 9 with EtP(O)(OH)2 yielded mixed phosphonates LM[OP(Et)(O)(OH)][OP(tBu)(O)(OH)] [M = Sb (7), M = Bi (10)]. All compounds were characterized by elemental analysis, ESI mass spectrometry, 1H, 13C and 31P NMR spectroscopy and IR spectroscopy. Molecular structures of compounds 4, 5, 8 and 9 were determined by using X‐ray single‐crystal diffraction in the solid state. Secondary phosphonates 4, 5 and 8 form weakly bonded dimeric units through hydrogen bridges of the type PO–H···O=P. On the other hand, compound 9 is trimeric in the solid state with the central 12‐membered ring formed by three LBi[O2P(tBu)(O)] building blocks through intermolecular Bi···O=P contacts.
Analysis of hemoglobin‐based oxygen carriers by CE‐UV/Vis and CE‐ESI‐TOF/MS
Authors: Staub Aline , Rudaz Serge , Saugy Martial , Veuthey Jean‐Luc , Schappler Julie 
Published: March 2010

AbstractBlood doping involves the use of products that enhance the uptake, transport, or delivery of oxygen to the blood. One approach uses artificial oxygen carriers, known as hemoglobin‐based oxygen carriers (HBOCs). This study describes an analytical strategy based on CE for detecting intact HBOCs in plasma samples collected for doping control. On‐capillary detection was performed by UV/Vis at 415 nm, which offered detection selectivity for hemoproteins (such as hemoglobin and HBOCs). On‐line ESI‐MS detection with a TOF analyzer was further used to provide accurate masses on CE peaks and to confirm the presence of HBOCs. An immunodepletion sample preparation step was mandatory prior to analysis, in order to remove most abundant proteins that interfered with CE separation and altered the ESI process. This analytical method was successfully applied to plasma samples enriched with Oxyglobin®, a commercially available HBOC used for veterinary purposes. Detection limits of 0.20 and 0.45 g/dL were achieved in plasma for CE‐UV/Vis at 415 nm and CE‐ESI‐TOF/MS, respectively.
Targeting and processing of site‐specific DNA interstrand crosslinks
Authors: Vasquez Karen M. 
Published: March 2010

AbstractDNA interstrand crosslinks (ICLs) are among the most cytotoxic types of DNA damage, and thus ICL‐inducing agents such as cyclophosphamide, melphalan, cisplatin, psoralen, and mitomycin C have been used clinically as anticancer drugs for decades. ICLs can also be formed endogenously as a consequence of cellular metabolic processes. ICL‐inducing agents continue to be among the most effective chemotherapeutic treatments for many cancers; however, treatment with these agents can lead to secondary malignancies, in part due to mutagenic processing of the DNA lesions. The mechanisms of ICL repair have been characterized more thoroughly in bacteria and yeast than in mammalian cells. Thus, a better understanding of the molecular mechanisms of ICL processing offers the potential to improve the efficacy of these drugs in cancer therapy. In mammalian cells, it is thought that ICLs are repaired by the coordination of proteins from several pathways, including nucleotide excision repair (NER), base excision repair (BER), mismatch repair (MMR), homologous recombination (HR), translesion synthesis (TLS), and proteins involved in Fanconi anemia (FA). In this review, we focus on the potential functions of NER, MMR, and HR proteins in the repair of and response to ICLs in human cells and in mice. We will also discuss a unique approach, using psoralen covalently linked to triplex‐forming oligonucleotides to direct ICLs to specific sites in the mammalian genome. Environ. Mol. Mutagen. 2010. © 2010 Wiley‐Liss, Inc.
Expressive writing and eating disorder features: A preliminary trial in a student sample of the impact of three writing tasks on eating disorder symptoms and associated cognitive, affective and interpersonal factors
Authors: East Philippa , Startup Helen , Roberts Clifford , Schmidt Ulrike 
Published: March 2010

AbstractObjectiveTo evaluate the impact of three writing tasks on the cognitive, affective and interpersonal factors typically associated with eating disorder symptoms, in a student population.MethodTwo experimental tasks and one control task were evaluated. Participants gave subjective ratings of the writing experience, and objective questionnaire measures were administered at baseline, and 4‐ and 8‐week follow‐up.ResultsParticipants who dropped out without completing the writing tasks were more experientially avoidant. The three tasks differed significantly in subjective impact, and the experimental tasks were most effective in reducing eating disorder symptoms. They also ameliorated some key features associated with eating difficulties. The control task generally had less, no or a detrimental effect.ConclusionThe results provide preliminary indirect support for the use of therapeutic writing to address specific features associated with the eating disorder presentation. Further research is required to replicate the present findings and extend these to the clinical population. Copyright © 2010 John Wiley & Sons, Ltd and Eating Disorders Association.
Selflessness and perfectionism as predictors of pathological eating attitudes and disorders: A longitudinal study
Authors: Bachar Eytan , Gur Eitan , Canetti Laura , Berry Elliot , Stein Daniel 
Published: March 2010

AbstractThis paper examines the role that selflessness and perfectionism may play as possible predictors of pathological eating attitudes and eating disorders (ED). 1057 schoolgirls (seventh to ninth grade) participated in the initial screening phase. They were administered the Eating Attitudes Test (EAT‐26), Selflessness Scale (SS) and Multidimensional Perfectionism Scale (MPS). Based on their EAT‐26 scores, 150 girls were invited to a clinical interview 2 years later (second phase). In the third phase 4 years later, 243 girls who completed the questionnaires in the seventh grade were the target of re‐administration of these scales. Seventh‐grade selflessness scores at initial screening phase predicted ED status determined in clinical interview at the 2‐year interval and abnormal eating attitudes at the 4‐year interval, above and beyond baseline seventh‐grade eating‐attitude scores. Perfectionism was not found to predict the development of neither ED nor abnormal eating attitudes. Preventional and therapeutic implications of the role of selflessness as a predisposing factor for ED are discussed. Copyright © 2010 John Wiley & Sons, Ltd and Eating Disorders Association.
The independent set perturbation adjoint method: A new method of differentiating mesh‐based fluids models
Authors: Fang F. , Pain C. C. , Navon I. M. , Gorman G. J. , Piggott M. D. , Allison P. A. 
Published: March 2010

AbstractA new scheme for differentiating complex mesh‐based numerical models (e.g. finite element models), the Independent Set Perturbation Adjoint method (ISP‐Adjoint), is presented. Differentiation of the matrices and source terms making up the discrete forward model is realized by a graph coloring approach (forming independent sets of variables) combined with a perturbation method to obtain gradients in numerical discretizations. This information is then convolved with the ‘mathematical adjoint’, which uses the transpose matrix of the discrete forward model. The adjoint code is simple to implement even with complex governing equations, discretization methods and non‐linear parameterizations. Importantly, the adjoint code is independent of the implementation of the forward code. This greatly reduces the effort required to implement the adjoint model and maintain it as the forward model continues to be developed; as compared with more traditional approaches such as applying automatic differentiation tools. The approach can be readily extended to reduced‐order models. The method is applied to a one‐dimensional Burgers' equation problem, with a highly non‐linear high‐resolution discretization method, and to a two‐dimensional, non‐linear, reduced‐order model of an idealized ocean gyre. Copyright © 2010 John Wiley & Sons, Ltd.
Comments on paratrooper‐separation modeling with the DSD/SST formulation and FOIST
Authors: Tezduyar Tayfun E. 
Published: March 2010

AbstractWe provide a brief chronological background on the deforming‐spatial‐domain/stabilized space–time (DSD/SST) formulation, its use in aerodynamic modeling of a paratrooper separating from an aircraft, and the fluid–object interactions subcomputation technique (FOIST). Copyright © 2010 John Wiley & Sons, Ltd.
Thermal model for optimization of vascular laser tissue soldering
Authors: Bogni Serge , Stumpp Oliver , Reinert Michael , Frenz Martin 
Published: March 2010

AbstractLaser tissue soldering (LTS) is a promising technique for tissue fusion based on a heat‐denaturation process of proteins. Thermal damage of the fused tissue during the laser procedure has always been an important and challenging problem. Particularly in LTS of arterial blood vessels strong heating of the endothelium should be avoided to minimize the risk of thrombosis. A precise knowledge of the temperature distribution within the vessel wall during laser irradiation is inevitable. The authors developed a finite element model (FEM) to simulate the temperature distribution within blood vessels during LTS. Temperature measurements were used to verify and calibrate the model. Different parameters such as laser power, solder absorption coefficient, thickness of the solder layer, cooling of the vessel and continuous vs. pulsed energy deposition were tested to elucidate their impact on the temperature distribution within the soldering joint in order to reduce the amount of further animal experiments. A pulsed irradiation with high laser power and high absorbing solder yields the best results. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)