bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kim Il-sung in the Soviet Army, 1940–1945: His Experience and Its Future Impact on the North Korean State and Armed Forces
Authors: Tertitski Konstantin , Tertitskiy Fyodor 
Published: June 2024

Abstract
This article traces the origins of North Korea's militarized, repressive political system. It shows that the policies of the country's founder, Kim Il-sung, were heavily influenced by his personal experience in the USSR, or, more precisely, in the Soviet armed forces in the early 1940s. This factor has been largely overlooked by the academic community up to now. Drawing on a wealth of new sources in Chinese, Korean, and Russian, the article discusses how Kim's service as a Soviet military officer shaped his worldview and approach to governing North Korea. Through a multifaceted analysis of the North Korean military, the article reveals how its size, doctrine, economic role, and political education system were all influenced by Kim's experiences and those of his fellow soldiers in the USSR's Red Army. This insight has broader implications for understanding North Korean civilian society. By shedding light on the formative experiences that shaped Kim's approach to governance, the article offers a new lens through which to view the country's political and social structures.
Beginning of Winter: The George H.W. Bush Administration, the Nagorno-Karabakh Conflict, and the Emergence of the Post–Cold War World
Authors: Stocker James R. 
Published: June 2024

Abstract
The conflict that arose between Soviet Armenia and Soviet Azerbaijan over Nagorno-Karabakh in 1988 festered throughout the final years of the Soviet Union and sparked a major war between the newly independent Armenia and Azerbaijan in 1992–1994. Most accounts of this period have suggested that the administration of George H. W. Bush took a largely hands-off approach to the Nagorno-Karabakh conflict, but this article shows that in fact the Bush administration pursued a much more active policy that reflected support for the Soviet Union and then Russia, a strong domestic Armenian-American lobby, and regional priorities, as well as a growing awareness of the West's failure to stem violence in Yugoslavia. The Bush administration was hoping to prevent all-out war between Armenia and Azerbaijan, but after the war began, the administration did what it could to try to limit and halt the violence.
Cold War Détente?: The Role of China in the Aftermath of Malaya's Failed Peace Talks in 1955
Authors: Yanqing He , Cheok Cheong Kee , Ran Li 
Published: June 2024

Abstract
After World War II, the struggle for independence in Southeast Asia was complicated by the onset of the Cold War and the involvement of major external powers in the region, especially the People's Republic of China (PRC). Amid Cold War tensions, an opportunity arose for détente in Malaya in the early 1950s, despite the failure of peace talks between the Malayan Communist Party (MCP) and the Malayan government. This opportunity arose from the PRC's proclaimed embrace of peaceful coexistence. Chinese leaders adopted the policy in the expectation that the new Malayan government would defer to China's wishes. This expectation proved unfounded; the government of independent Malaya had no desire to be subservient to the PRC. The adverse turn of events for China, and the subsequent emergence of a rift between Moscow and Beijing, thwarted efforts to establish formal ties between the MCP and the Malayan government, prompting the Malayan Communists to resume their campaign of guerrilla warfare.
Overcoming a Cold War Mindset: Encounters with Soviet Musical Expertise in a Finnish Town
Authors: Mikkonen Simo , Okko Antti 
Published: June 2024

Abstract
This article examines how a music festival in a regional Finnish town managed to overcome concrete and imagined Cold War limitations to become a venue for sustained encounters between Soviet and Western musicians starting in the mid-1960s. It explains how the Jyväskylä Summer Festival, which began in 1956 as one of the first festivals of its kind in the Nordic countries, acted as an intermediary and managed to secure contracts for several high-profile Soviet musicians to perform and provide master classes for up to a month, with relatively little surveillance from the Soviet state security apparatus, allowing for deeper interaction among Eastern and Western participants. Although many obstacles and challenges had to be overcome, the use of music and art to ease Cold War tensions proved beneficial to both the USSR and Finland and helped reduce cultural stereotypes, introduce new forms of music, improve performer agency, promote careers, and open doors to opportunities for long-term cooperation between previously separated societies.
The spatiotemporal profile and adaptation determine the joint effects and interactions of multiple stressors
Authors: Streib Lucas , Spaak Jurg W. , Kloft Marius , Schäfer Ralf B. 
Published: June 2024

Abstract
Background
Biodiversity is declining worldwide as ecosystems are increasingly threatened by multiple stressors associated with anthropogenic global change. Stressors frequently co-occur across scales spatially and temporally, resulting in joint effects that are additive or non-additive, i.e., antagonism or synergism. Forecasting and counteracting threats from intensifying stressors requires improved mechanistic understanding of joint effects, which is currently relatively low. To date, research on multiple stressors has been biased toward simplified scenarios, emphasized classification of interactions over realized joint effects, and mostly ignored adaptation (i.e., phenotypic plasticity or evolving life-history traits) of organisms. To investigate if more a realistic scenarios design incorporating complex spatiotemporal stressor profiles and adaption change joint effects and interactions of multiple stressors compared to simplified scenarios, we modified a spatially explicit meta-population model for a generic freshwater insect. We used the model to simulate different, hypothetical spatiotemporal profiles of a continuous and a discrete stressor and evaluated their joint effects and interactions. Agricultural land use represented the continuous stressor impacting meta-population patch quality and network connectivity and related scenarios implied different trajectories. Climatic events represented the discrete stressor impacting all patches simultaneously by temporary mortality events, with related scenarios implying different event severity. Adaptation mitigated the effects of climatic events based on previous events.

Results
Excluding adaptation, we found that at higher levels of the discrete stressor (i.e., strong and frequent climatic events) it strongly dominates the joint effects, while at a low level (i.e., weak and infrequent climatic events) of the discrete stressor, the continuous stressor (i.e., land use) dominates. Yet, the continuous stressor always defined the interaction type, with decreasing land use stress leading to antagonism, and increasing land use stress leading to synergism. Adaptation reduced joint effects under decreasing land use stress, yet had little compensatory influence under increasing land use stress. Moreover, adaptation changed interaction sizes inconsistently across the different land use and climate scenarios, with change depending on the climate scenario. Here, interactions decreased in the moderate scenario but increased in the severe and intense scenarios.

Conclusions
We highlight that realistic stressor scenarios accounting for potential adaptation are critical for a mechanistic understanding of how species respond to global change. To our knowledge, this is the first modeling study to show that stressor interactions depend on complex spatiotemporal stressor profiles and adaptation, following general principles.
Advancements in understanding the role of intestinal dysbacteriosis mediated mucosal immunity in IgA nephropathy
Authors: Fan Yitao , Wang Yan , Xiao Han , Sun Hui 
Published: June 2024

AbstractIgA nephropathy, presently recognized as the foremost primary glomerular disorder, emerges as a principal contributor to renal failure globally, with its pathogenesis yet to be fully elucidated. Extensive research has highlighted the critical role of gut microbiome in the onset and progression of IgA nephropathy, underscoring its importance in accurately delineating the disease’s etiology. For example, gut microbiome dysbacteriosis can lead to the production of nephritogenic IgA1 antibodies, which form immune complexes that deposit in the kidneys, causing inflammation and damage. The gut microbiome, a source of numerous bioactive compounds, interacts with the host and plays a regulatory role in gut-immune axis modulation, earning it the moniker of the “second brain.” Recent investigations have particularly emphasized a significant correlation between IgA nephropathy and gut microbiome dysbacteriosis. This article offers a detailed overview of the pathogenic mechanisms of IgA nephropathy, specifically focusing on elucidating how alterations in the gut microbiome are associated with anomalies in the intestinal mucosal system in IgA nephropathy. Additionally, it describes the possible influence of gut microbiome on recurrent IgA nephropathy following kidney transplantation. Furthermore, it compiles potential therapeutic interventions, offering both theoretical and practical foundations for the management of IgA nephropathy. Lastly, the challenges currently faced in the therapeutic approaches to IgA nephropathy are discussed.
Patient-perceived barriers to early initiation of prenatal care at a large, urban federally qualified health center: a mixed-methods study
Authors: Holt Valerie N. , Pelegrí Elan , Hardy Mary , Buchin Lindsey , Dapkins Isaac , Chuang Meleen 
Published: June 2024

Abstract
Background
Early initiation of prenatal care is widely accepted to improve the health outcomes of pregnancy for both mothers and their infants. Identification of the various barriers to entry into care that patients experience may inform and improve health care provision and, in turn, improve the patient’s ability to receive necessary care.

Aim
This study implements a mixed-methods approach to establish methods and procedures for identifying barriers to early entry to prenatal care in a medically-vulnerable patient population and areas for future quality improvement initiatives.

Methods
An initial chart review was conducted on obstetrics patients that initiated prenatal care after their first trimester at a large federally qualified health center in Brooklyn, NY, to determine patient-specified reasons for delay. A thematic analysis of these data was implemented in combination with both parametric and non-parametric analyses to characterize the population of interest, and to identify the primary determinants of delayed entry.

Results
The age of patients in the population of interest (n = 169) was bimodal, with a range of 15 – 43 years and a mean of 28 years. The mean gestational age of entry into prenatal care was 19 weeks. The chart review revealed that 8% recently moved to Brooklyn from outside of NYC or the USA. Nine percent had difficulty scheduling an initial prenatal visit within their first trimester. Teenage pregnancy accounted for 7%. Provider challenges with documentation (21%) were noted. The most common themes identified (n = 155) were the patient being in transition (21%), the pregnancy being unplanned (17%), and issues with linkage to care (15%), including no shows or patient cancellations. Patients who were late to prenatal care also differed from their peers dramatically, as they were more likely to be Spanish-speaking, to be young, and to experience a relatively long delay between pregnancy confirmation and entry into care. Moreover, the greatest determinant of delayed entry into care was patient age.

Conclusion
Our study provides a process for other like clinics to identify patients who are at risk for delayed entry to prenatal care and highlight common barriers to entry. Future initiatives include the introduction of a smart data element to document reasons for delay and use of community health workers for dedicated outreach after no show appointments or patient cancellations.
Do promotions of healthier or more sustainable foods increase sales? Findings from three natural experiments in UK supermarkets
Authors: Luick Madison , Bandy Lauren , Piernas Carmen , Jebb Susan A. , Pechey Rachel 
Published: June 2024

Abstract
Background
Dietary changes are necessary to improve population health and meet environmental sustainability targets. Here we analyse the impact of promotional activities implemented in UK supermarkets on purchases of healthier and more sustainable foods.

Methods
Three natural experiments examined the impact of promotional activities on sales of a) no-added-sugar (NAS) plant-based milk (in 199 stores), b) products promoted during ‘Veganuary’ (in 96 stores), and c) seasonal fruit (in 100 non-randomised intervention and 100 matched control stores). Data were provided on store-level product sales, in units sold and monetary value (£), aggregated weekly. Predominant socioeconomic position (SEP) of the store population was provided by the retailer. Analyses used interrupted time series and multivariable hierarchical mixed-effects models.

Results
Sales of both promoted and total NAS plant-based milks increased significantly during the promotional period (Promoted:+126 units, 95%CI: 105–148; Overall:+307 units, 95%CI: 264–349). The increase was greater in stores with predominately low SEP shoppers. During Veganuary, sales increased significantly for plant-based foods on promotion (+60 units, 95%CI: 37–84), but not for sales of plant-based foods overall (dairy alternatives: -1131 units, 95%CI: -5821–3559; meat alternatives: 1403 units, 95%CI: -749–3554). There was no evidence of a change in weekly sales of promoted seasonal fruit products (assessed via ratio change in units sold: 0.01, 95%CI: 0.00–0.02), and overall fruit category sales slightly decreased in intervention stores relative to control (ratio change in units sold: -0.01, 95%CI: -0.01–0.00).

Conclusion
During promotional campaigns there was evidence that sales of plant-based products increased, but not seasonal fruits. There was no evidence for any sustained change beyond the intervention period.
Medicinal flora of the baiku yao people — An ethnobotanical documentation in South China
Authors: Li Tingting , Luo Binsheng , Tong Yuanming , Wei Guiyuan , Chai Ling , Hu Renchuan 
Published: June 2024

Abstract
Background
This study explores the medicinal plant knowledge of the Baiku Yao, a unique ethnic group in China. Despite existing research on their ethnobotanical practices, a comprehensive understanding of their medicinal flora remains lacking. This study aims to document and analyze the species distribution, utilization, and traditional knowledge of medicinal plants used by Baiku Yao.

Methods
Ethnobotanical surveys were conducted in various Baiku Yao villages across different seasons from 2019 to 2023. Informants were interviewed, and plant specimens were collected and identified. Statistical analyses, including the Relative Frequency of Citation (RFC), were employed to understand plant importance in Baiku Yao culture.

Results
In an ethnobotanical survey conducted in the Baiku Yao region, 434 medicinal plant species were documented, highlighting significant ethnobotanical diversity and a deep cultural integration of traditional medicinal practices. The study revealed pronounced geographical variations in plant knowledge among villages, with a notable reliance on wild plants, as 85.48% were sourced from the wild, reflecting unique local ethnobotanical knowledge. Predominantly herbs and shrubs were used due to their accessibility and abundance in the local environment. High Relative Frequency of Citation (RFC) values for certain species underscored their importance for local health needs and additional economic value. The utilization of various plant parts, particularly whole plants, roots, and leaves, indicates a holistic approach to medicinal applications, adapted to combat prevalent health issues such as skin and infectious diseases. The study also uncovered the Baiku Yao’s cultural practices for countering “Gu” afflictions—a range of pathogenic conditions—with 18 diverse antidote plants used for skin, digestive, and musculoskeletal disorders. The study underscores the imperative of preserving this rich medicinal heritage through innovative models that engage youth and leverage new media, ensuring the inheritance and evolution of Baiku Yao’s traditional knowledge.

Conclusions
Baiku Yao’s medicinal plant use reflects a deep, culturally ingrained knowledge, closely tied to local ecology. The study highlights the importance of preserving this unique ethnobotanical heritage and suggests interdisciplinary approaches for future research.
COVID-19 healthcare success or failure? Crisis management explained by dynamic capabilities
Authors: Rosenbäck Ritva , Eriksson Kristina M. 
Published: June 2024

Abstract
Introduction
This paper presents a structured review of the use of crisis management, specifically examining the frameworks of surge capacity, resilience, and dynamic capabilities in healthcare organizations. Thereafter, a novel deductive method based on the framework of dynamic capabilities is developed and applied to investigate crisis management in two hospital cases during the COVID-19 pandemic.

Background
The COVID-19 pandemic distinguishes itself from many other disasters due to its global spread, uncertainty, and prolonged duration. While crisis management in healthcare has often been explained using the surge capacity framework, the need for adaptability in an unfamiliar setting and different information flow makes the dynamic capabilities framework more useful.

Methods
The dynamic capabilities framework’s microfoundations as categories is utilized in this paper for a deductive analysis of crisis management during the COVID-19 pandemic in a multiple case study involving two Swedish public hospitals. A novel method, incorporating both dynamic and static capabilities across multiple organizational levels, is developed and explored.

Results
The case study results reveal the utilization of all dynamic capabilities with an increased emphasis at lower organizational levels and a higher prevalence of static capabilities at the regional level. In Case A, lower-level managers perceived the hospital manager as brave, supporting sensing, seizing, and transformation at the department level. However, due to information gaps, sensing did not reach regional crisis management, reducing their power. In Case B, with contingency plans not initiated, the hospital faced a lack of management and formed a department manager group for patient care. Seizing was robust at the department level, but regional levels struggled with decisions on crisis versus normal management. The novel method effectively visualizes differences between organizational levels and cases, shedding light on the extent of cooperation or lack thereof within the organization.

Conclusion
The researchers conclude that crisis management in a pandemic, benefits from distributed management, attributed to higher dynamic capabilities at lower organizational levels. A pandemic contingency plan should differ from a plan for accidents, supporting the development of routines for the new situation and continuous improvement. The Dynamic Capabilities framework proved successful for exploration in this context.
Associations between the TyG index and the ɑ-Klotho protein in middle-aged and older population relevant to diabetes mellitus in NHANES 2007–2016
Authors: Qiu Shujuan , Li Chunlei , Zhu Jinhua , Guo Zhentao 
Published: June 2024

Abstract
Background
The anti-aging protein Klotho has diverse functions in antioxidative stress and energy metabolism through several pathways. While it has been reported that α-Klotho is downregulated in patients with insulin resistance (IR), the association between Klotho and IR is complex and controversial. The triglyceride-glucose (TyG) index has provided a practical method for assessing IR. With this in mind, our study aimed to investigate the relationship between the TyG index and soluble α-Klotho protein levels in US populations, both with and without diabetes mellitus.

Methods
This cross-sectional study analyzed data from middle-aged and older participants in the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2016. The participants were divided into two groups based on their diabetes mellitus status: those with diabetes and those without diabetes. To evaluate the relationship between the TyG index and the concentration of the α-Klotho protein in each group, a series of survey-weighted multivariable linear regression models were employed. Furthermore, to examine the association between these two variables, multivariable-adjusted restricted cubic spline curves and subgroup analysis were generated.

Results
The study involved 6,439 adults aged 40 years or older, with a mean age of 57.8 ± 10.9 years. Among them, 1577 (24.5%) had diabetes mellitus. A subgroup analysis indicated that the presence of diabetes significantly affected the relationship between the TyG index and the α-Klotho level. After considering all covariables, regression analysis of the participants without diabetes revealed that the α-Klotho concentration decreased by 32.35 pg/ml (95% CI: -50.07, -14.64) with each one unit increase in TyG (p < 0.001). The decline in α-Klotho levels with elevated TyG was more pronounced in the female population. In patients with diabetes mellitus, a non-linear association between the TyG index and α-Klotho was observed. There was no significant correlation observed between the two when TyG index were below 9.7. However, there was an increase in klotho levels of 106.44 pg/ml for each unit increase in TyG index above 9.7 (95% CI: 28.13, 184.74) (p = 0.008).

Conclusion
Our findings suggested that the presence of diabetes may influence the relationship between the TyG index and soluble α-Klotho. Furthermore, there seem to be sex differences in individuals without diabetes. Further studies are necessary to validate these findings.
Identification of the central role of RNA polymerase mitochondrial for angiogenesis
Authors: Huan Meng-Jia , Fu Ping-ping , Chen Xia , Wang Zhao-Xia , Ma Zhou-rui , Cai Shi-zhong , Jiang Qin , Wang Qian 
Published: June 2024

AbstractMitochondria are central to endothelial cell activation and angiogenesis, with the RNA polymerase mitochondrial (POLRMT) serving as a key protein in regulating mitochondrial transcription and oxidative phosphorylation. In our study, we examined the impact of POLRMT on angiogenesis and found that its silencing or knockout (KO) in human umbilical vein endothelial cells (HUVECs) and other endothelial cells resulted in robust anti-angiogenic effects, impeding cell proliferation, migration, and capillary tube formation. Depletion of POLRMT led to impaired mitochondrial function, characterized by mitochondrial depolarization, oxidative stress, lipid oxidation, DNA damage, and reduced ATP production, along with significant apoptosis activation. Conversely, overexpressing POLRMT promoted angiogenic activity in the endothelial cells. In vivo experiments demonstrated that endothelial knockdown of POLRMT, by intravitreous injection of endothelial specific POLRMT shRNA adeno-associated virus, inhibited retinal angiogenesis. In addition, inhibiting POLRMT with a first-in-class inhibitor IMT1 exerted significant anti-angiogenic impact in vitro and in vivo. Significantly elevated expression of POLRMT was observed in the retinal tissues of streptozotocin-induced diabetic retinopathy (DR) mice. POLRMT endothelial knockdown inhibited pathological retinal angiogenesis and mitigated retinal ganglion cell (RGC) degeneration in DR mice. At last, POLRMT expression exhibited a substantial increase in the retinal proliferative membrane tissues of human DR patients. These findings collectively establish the indispensable role of POLRMT in angiogenesis, both in vitro and in vivo.