bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphometric analysis of proximal femur in Indian population and its implications in Total Hip Arthroplasty
Authors: Contractor Jaikumar B , Umraniya Bhavika , Singh Praveen 
Published: May 2024

Geometric understanding of the proximal end of femur is significant for functional bipedal erect posture and in pre-operative planning of osteotomy as well as the design and development of implants for THA. Moreover, the anthropological parameters of any bone are determined by genetic and environmental factors such as age, race, gender and lifestyle and this leads to racial variations in the morphological parameters of proximal end of femur owing to lifestyle, physique, applied force and their distribution in India population.The current study was designed to study and compare the morphology of proximal end of femur in Indian population and was conducted on 94 dry human cadaveric bones of unknown age and sex to determine the morphology of the proximal end of femur. We observed the Femur Length as 426.6 ± 15.82 mm, Femur Neck Length as 3.455 ± 0.378 mm and Neck Shaft Angle as 125.27 ± 2.54° amongst other parameters.The findings also revealed significant variations in the morphological parameters among different populations, emphasizing the importance of considering racial diversity in the design and selection of implants for THA for improving the success and longevity of hip arthroplasty procedures.
Incomplete oblique fissure with absence of lingula, cardiac notch in left lung: A case report
Authors: Dsouza Schwetha Cheryl , Nayak Sabita , Nazmeen Silotry  
Published: May 2024

: Lungs, are partitioned into distinct lobes by fissures. These anatomical fissures play a crucial role in ensuring the consistent expansion of each lobe during the process of respiration. The left lung, comprises of two main lobes: the upper lobe and the lower lobe, delineated by an oblique fissure. We present a case of an incomplete oblique fissure, accompanied by the absence of both the lingula and the cardiac notch in the left lung of a male cadaver. This anatomical variation was discovered during a routine thoracic dissection. No structural alterations were noted at the hilum of the left lung. The Fissures and hilum on the right lung were normal. Understanding morphological variations in fissures and lobes is useful when identifying lung lesions, planning invasive respiratory operations, and analyzing diagnostic imaging. It emphasizes the practical consequences of anatomical variation in the context of respiratory operations and imaging interpretations, highlighting the importance of incorporating it into medical teaching and practice.
Estructura del Programa Nacional para la Prevención del Suicidio en México
Authors: Vazquez Alejandro , Arenas Landgrave Paulina , Tejadilla Orozco Diana Iris , Espinosa Méndez Pamela 
Published: May 2024

ANTECEDENTES: Durante las últimas dos décadas las tasas de suicidio disminuyeron en todas las regiones del mundo, excepto en la región de las Américas; en México, incrementaron especialmente en el grupo de adolescentes y jóvenes. En atención a esta problemática, México ocupa el sexto lugar en la región de las Américas en desarrollar durante el 2020, un Programa Nacional para la Prevención de Suicidio (PRONAPS) que lo aborda desde una perspectiva contextual de salud pública.
OBJETIVO: Describir la estructura del Programa Nacional para la Prevención de Suicidio en México, con base en el modelo de Redes Integradas de Servicios de Salud y el modelo escalonado de atención al riesgo suicida, Modelo Dinámico de Órdenes de Riesgo de Suicidio (MODORIS).
RELEVANCIA: Una de las principales estrategias para la prevención del suicidio a nivel global es aumentar el acceso a los servicios de salud, el cual debe acompañarse de una atención de calidad fundamentada en el abordaje, manejo y tratamiento de la suicidalidad desde modelos con evidencia clínica, que puedan implementarse desde la comunidad hasta los servicios de salud especializados. Estas acciones se priorizan en el PRONAPS bajo cinco ejes centrales: organización y coordinación intersectorial e interinstitucional; vigilancia epidemiológica; intervención; capacitación; e investigación, para proporcionar y sostener una atención integral a las personas con riesgo suicida. Es la primera vez en el país que se estructuran e implementan estas acciones de manera articulada a nivel intersectorial, por lo que uno de los principales retos del PRONAPS es mantener su gobernanza.
Intentos de suicidio atendidos en un servicio de urgencias pediátrico, antes y durante la pandemia de COVID-19
Authors: Casas Muñoz Abigail , Mondragón María del Carmen Obregón , Caballero Aarón Rodríguez , Rojano Ángel Eduardo Velasco , Pérez Nahomi Patricia Gallardo , Rangel Rosa Valentina Vega , Peralta Victoria Abril Agatón , González Ivanna Sofía Barrón , Ortega Diana Laura Sandoval 
Published: May 2024

Antecedentes. El suicidio es un problema de salud pública. Los intentos suicidas (IS) en adolescentes aumentaron drásticamente durante la pandemia de COVID-19.
Objetivo. Identificar la frecuencia de los casos de IS atendidos en el servicio de urgencias por temporalidad (en los últimos cinco años) y describir los posibles factores de riesgo y/o posibles desencadenantes y algunas características del IS así como de la solicitud de atención.
Material y Métodos. Estudio observacional, retrospectivo y descriptivo de revisión de expedientes, de 2018 a 2023.
Resultados. Se revisaron 296 expedientes con el diagnóstico de IS. El 74% fueron mujeres, 56% eran adolescentes tardíos, 43% tempranos y 1% niños. Hubo un 266% de incremento de los casos atendidos por IS durante la pandemia. Por temporalidad en el mes de enero prepandemia la cantidad de casos fue más alta y durante la pandemia disminuyó, sucedió de manera inversa para los meses de febrero, marzo, julio y septiembre. Los principales factores de riesgo y/o desencadenantes fueron: los conflictos interpersonales (64.19%), el estrés social (57.43%), la agudización de un trastorno de salud mental previo (56.08%), el antecedente de IS previo (48.31%), divorcio de los padres (31.42%) y vivir diferentes formas de violencia [psicológica (28.33%), sexual (18.92%) y por pares (16.55%)]. El horario de solicitud de atención se concentró principalmente en los turnos vespertino y nocturno (79.39%).
Conclusiones. Durante la pandemia hubo un incremento en la cantidad de casos atendidos por Intento de Suicidio en adolescentes en el servicio de urgencias y cambios en la temporalidad de presentación.
O protocolo spikes na comunicação de más notícias em saúde: revisão integrativa
Authors: Girardi José Marcos , Andrade Beatriz Amélia Monteiro de , Leao Flavio Rogerio de Carvalho , Protazio Mairla Machado , Oliveira Márcia Pedrosa de , Chaves Cristianne Soares 
Published: May 2024

Introdução: A competência de comunicação em saúde exigida para o cuidado está associada a melhores resultados e maiores índices de satisfação, em especial quando profissionais fornecem más notícias, que alteram negativamente a visão do paciente sobre seu futuro. O protocolo SPIKES, realizado em seis etapas, é abordagem didática relacionada ao câncer, mas tem sido usado em diversos cenários clínicos, como em doenças crônico-degenerativas e infertilidade, destacando o direito do paciente de não saber. Intervenções educacionais parecem eficazes para ensinar os educandos a lidar com esta competência. Objetivo: Identificar o papel do protocolo SPIKES na comunicação de más notícias em saúde. Metodologia: Busca bibliográfica de artigos em línguas inglesa ou portuguesa realizada no mês de agosto de 2023 nas bases eletrônicas de dados da literatura em saúde (MEDLINE e LILACS via BIREME, PUBMED, SciELO e SCOPUS), utilizando os termos “communication in health”, AND “breaking bad News” AND “SPIKES protocol”, sem limitação para o ano de publicação. Resultados: De 175 artigos incialmente identificados foram selecionados 39, excluídos aqueles que não atendiam à pesquisa, permanecendo 19 que embasaram a revisão. O protocolo SPIKES é plataforma valiosa, cujos modelos de comunicação centrados nas preferências dos pacientes podem resultar em melhores resultados de tratamento. Conclusão: Comunicação de más notícias é tarefa difícil para profissionais de saúde, para a qual a educação médica oferece pouca preparação, pois as habilidades de comunicação não são parte essencial dos currículos. O protocolo SPIKES fornece mensagem clara e compreensível de acordo com as necessidades e desejos dos pacientes.
OECD countries' main contributors to families emerging above the poverty line
Authors: Oyarzo Felipe , Asher Trixi , DuBose Erika , Smith Shannon , Harrison Chris 
Published: May 2024

The reduction of poverty rates remains a challenging battle for most OECD governments, numerous international organizations, philanthropic associations, and a subject of study for many research centers. In this analysis, 200 empirical governmental documents, international reports, and peer-reviewed scientific publications regarding poverty reduction were meta-analyzed to identify the strongest factors in reducing poverty among OECD countries. A quantitative exploration of the literature using a statistical correlational research design showed that positive political leadership, effective economic and policy-making, low crime rates, low corruption rates, employment, higher earnings, familial support, greater access to higher education, age, physical and cognitive disability, physical health, mental health, positive cultural factors (mentality, values, etc.), access to clean water and food, housing, location, relocation, government support, communal support, scientific development (technology and innovation), and availability of production resources were found to be the most significant areas associated with the reduction of poverty among OECD countries in 2023. An analysis of the findings and suggestions for policymaking and research are also offered.
Keywords: Economy; economic mobility; OECD; poverty, poverty reduction; social mobility
MEDIATING ROLE OF TRUST ON VISIT INTENTION: MUSLIM FRIENDLY TOURISM IN TANA TORAJA
Authors: Fasiha Fasiha , Hamida Ambas , Jabani Muzzayanah , Rusli Muhammad 
Published: May 2024

This study evaluated the relationship between attitudes, subjective norms and perceived behavior control by using visit intention as a moderating variable and trust as a mediating variable. This study used quantitative research. The population in this study were Muslim tourists who visited tourist attractions in Tana Toraja district. Sampling used a purposive sampling with certain criteria. Data collection techniques used a questionnaire method. Meanwhile, data analysis in this study used SEM PLS. The results showed that a comprehensive trust mediation was found in the perception relationship between behavioral control and visit intention for Muslim-friendly tourism behavior, while in the attitude relationship, subjective norms toward visit intention Muslim-friendly tourism were found to be partial mediation. In other words, the model proposed to form a fundamental change in the visiting intention pattern of Muslim-friendly tourism for tourists was not running optimally. However, this study still finds it important that trust is able to mediate the relationship between perceptions of behavior control and visit intention in Muslim-friendly tourism. This research had two contributions, namely empirical evidence and policy. The results of this study were additional literature related to evidence of the development of the Muslim-friendly tourism trust on visit intention model. In addition, the results of this study helped the tourism agency achieve sustainable development
Coccydynia
Authors: Daily Drayton , Bridges James , Mo William B. , Mo Andrew Z. , Massey Patrick Allan , Zhang Andrew S 
Published: May 2024

» Coccydynia is a painful condition affecting many patients at the terminal caudal end of the spine.» An understanding of coccyx anatomy and variations of morphology is necessary for proper diagnosis. A multifactorial etiology for pain may be responsible for this clinical entity.» Several treatment options exist. Successful outcomes for patients depend on individual patient characteristics and the etiology of pain.
Uncovering Integrated STEM Attitudes and Dimensional Correlations in Education
Authors: Ummah Munfiathul , Shofiyah Noly 
Published: May 2024

This study investigates the attitudes towards STEM among junior high school students at Muhammadiyah Sidoarjo in Indonesia, focusing on exploring the degree of attitude towards STEM and examining the relationship between STEM dimensions. Using a survey method with 85 students from a population of 326, the research found that students' attitudes were most pronounced in the integrated STEM dimension, followed by engineering, technology, science, and mathematics. However, correlations between certain STEM dimensions and STEM itself were inconsistent, highlighting nuances in students' perceptions. These findings contribute to enhancing STEM education strategies, particularly in schools with integrated STEM-based learning, and suggest avenues for further research in broader educational contexts. Highlight: Examining STEM attitudes in Muhammadiyah Sidoarjo's junior high. Analyzing correlations between STEM dimensions and their implications. Enhancing STEM education strategies in Indonesia's educational context. Keyword: STEM education, Attitude assessment, Muhammadiyah Sidoarjo, Junior high school, Indonesia
Oral 8-aminoguanine against age-related retinal degeneration
Authors: Chen Yuanyuan , Vats Abhishek , Xi Yibo , Wolf-Johnston Amanda , Clinger Owen , Arbuckle Riley , Dermond Chase , Li Jonathan , Stolze Donna , Sahel José-Alain , Jackson Edwin , Birder Lori 
Published: May 2024

Abstract

Visual decline in the elderly is often attributed to retinal aging, which predisposes the tissue to pathologies such as age-related macular degeneration. Currently, effective oral pharmacological interventions for retinal degeneration are limited. We present a novel oral intervention, 8-aminoguanine (8-AG), targeting age-related retinal degeneration, utilizing the aged Fischer 344 rat model. A low-dose 8-AG regimen (5 mg/kg body weight) via drinking water, beginning at 22 months for 8 weeks, demonstrated significant retinal preservation. This was evidenced by increased retinal thickness, improved photoreceptor integrity, and enhanced electroretinogram responses. 8-AG effectively reduced apoptosis, oxidative damage, and microglial/macrophage activation associated with aging retinae. Age-induced alterations in the retinal purine metabolome, characterized by elevated levels of inosine, hypoxanthine, and xanthine, were partially mitigated by 8-AG. Transcriptomics highlighted 8-AG's anti-inflammatory effects on innate and adaptive immune responses. Extended treatment to 17 weeks further amplified the retinal protective effects. Moreover, 8-AG showed temporary protective effects in the RhoP23H/+ mouse model of retinitis pigmentosa, reducing active microglia/macrophages. Our study positions 8-AG as a promising oral agent against retinal aging. Coupled with previous findings in diverse disease models, 8-AG emerges as a promising anti-aging compound with the capability to reverse common aging hallmarks.
In vitro simulation of oral gastric intestinal digestion and fecal fermentation of Cordyceps militaris polysaccharides reveal its digestion profile and effect on the modulation of the gut microbiota
Authors: Yang Zheng-Guo , Fan Si-Yao , Liu Qi , Xu Wen-Man , Piao Hongjie , Ji Wen-Xiu , Dong Wei-Wei 
Published: May 2024

Abstract

Background: Polysaccharides isolated from Cordyceps militaris mycelia (IPS) are natural polymer compounds composed of monosaccharides, structurally diverse and exhibit various metabolic and biological activities. Nevertheless, as is well known, the lack of enzymes in the human body that can degrade polysaccharides results in a series of polysaccharides such as IPS not being directly absorbed and utilized, thereby greatly reducing their subsequent effects and efficacy in the body.
Results: In simulated saliva, the total carbohydrate, reducing sugar, and free monosaccharide content of IPS remained unchanged, while in the simulated gastric juice, the reduced sugar content of IPS increased from 0.0398 ± 0.0007 mg/mL to 0.072 ± 0.0053 mg/mL, and in intestinal fluid, it decreased from 0.0721 ± 0.0008 mg/mL to 0.0452 ± 0.0010 mg/mL. The carbohydrate content, reduced sugar content, and pH of IPS decreased from 0.1032 ± 0.0058 to 0.0.0722 ± 0.0067, 0.1392 ± 0.0055 to 0.0.0582 ± 0.0009 mg/mL, and 9.27 to 6.92, respectively, during simulated fermentation. Simultaneously, IPS regulated the gut microbiota, increasing the relative abundance of Firmicutes while reducing the relative abundance of Proteobacteria and Escherichia shigella. The IPS group also showed an increase in the concentration of short-chain fatty acids during fermentation.
Conclusions: IPS can be utilized by intestinal microbes to produce SCFAs and regulate the composition of intestinal flora, and can be helpful for better understanding of the potential digestion and fermentation mechanism of IPS.
High Order DIP-VBTV: An Image Restoration Model Combining a Deep Image Prior and a High Order Total Variation on Vector Bundles
Authors: Batard Thomas 
Published: May 2024

Abstract

We introduce a high order Total Variation (TV) for sections of vector bundles over Riemannian manifolds, and which is determined by the following geometric quadruplet: a connection and a positive definite metric on the vector bundle as well as a connection and a positive definite metric on the tangent bundle of the manifold. Then, we insert the high order TV into the Deep Image Prior (DIP), yielding a variational model for the restoration of grey-level and color images. The proposed model can be viewed as a combination of three classes of efficient variational models for image restoration: high order TV-based models which promotes the reconstruction of both edges and fine structures of the original image, geometric TV-based models which can encode extra properties of natural images, and DIP-based models which take benefit of the generative property of neural networks to reconstruct the original image. Experiments conducted up to the order 3 for image deblurring show that the higher the order, the better the results. Moreover, for a given order, the experiments also show that the proposed model outperforms its Euclidean restriction.
Political Influence and firms’ behavior in the framework of transition risk: Evidence from a Survey of EU enterprises
Authors: Quatrosi Marco 
Published: May 2024

Abstract

The EU has already issued the objectives to be complied with by Member States by 2050. On the other hand, enterprises face the effects of a changing climate mostly related to the increase in the likelihood of extreme events (physical risk) and uncertainty of the policy framework (transition risk). In this framework, this work will try to assess whether political pressure through different channels (e.g., lobbying, political connections, corruption) can be related to regulatory uncertainty. Results show that firms that perceive the environment as an obstacle also use political pressure to influence government decisions. However, despite the quality of government, there is still a component of uncertainty in the regulatory framework, especially in non-manufacturing enterprises. Thus, besides pure lobbying, firms can use political pressure to hedge from regulatory uncertainty. Results also highlight that firms that perceive environmental regulations as obstacles are also those that think more public funding should be channeled to the environment. This work sheds further light on the relationship between environmental regulations, political pressure and policy uncertainty. It also proves that transition risk is a concrete issue even in contexts where environmental objectives have been clearly set such as the European Union.
Genome-wide identification of high-affinity nitrate transporter 2 (NRT2) gene family in alfalfa (Medicago sativa)
Authors: Luo Yanyan , Nan Lili 
Published: May 2024

Abstract

The high-affinity nitrate transporter 2 (NRT2) proteins plays an important role in nitrate uptake and transport in plants. In this study, the NRT2s gene family was systematically analyzed in alfalfa. We showed that a total of three NRT2 members were identified from the genome database, according to their chromosomal location, they were named MsNRT2.1-2.3. The phylogenetic tree revealed that NRT2 proteins were categorized into two main subgroups, which was further confirmed by their gene structure and conserved motifs. Three MsNRT2 genes distributed on 2 chromosomes. Furthermore, we studied the expression pattern of MsNRT2 gene in six tissues based on RNA-sequencing data from the Short Read Archive (SRA) database of NCBI, and the results showed that MsNRT2 gene was widely expressed in six tissues. After treatment with drought, salt, abscisic acid (ABA) and salicylic acid (SA), We used quantitative RT-PCR to analyze the expression levels of MsNRT2 genes and the results showed that most of the MsNRT2 genes responded to these stresses. However, the individual genes play a major role under the different treatment conditions. In summary, MsNRT2 plays an irreplaceable role in the growth, development and stress response of alfalfa, and this study provides valuable information and theoretical basis for future research on MsNRT2 function.
Threshold Preview-able Essential Secret Image Sharing
Authors: Chen Shang-Kuan , Hsu Mao-Hsiu 
Published: May 2024

Abstract

This study investigates an essential secret image sharing scheme, which entails encoding a confidential image into two distinct sets of shadows referred to as essential shadows and non-essential shadows. This dual-shadow strategy is designed to fault-tolerantly and differentially preserve the confidentiality of the secret image. However, the inherent limitations of the essential secret image sharing mechanism become apparent when the number of shadows falls below the specified threshold, making the recovery of the secret image based solely on essential shadows unattainable. The reliance on non-essential shadows in such instances presents a dilemma for users. In response to this challenge, the present paper introduces a novel threshold preview-able essential secret image sharing method. In this approach, upon receiving a sufficient number of essential shadows, a preview of the distorted version of the secret image becomes possible. The proposed mechanism extends its applicability to two primary variations of threshold preview-able essential secret image sharing: (t, s, k, n)- and (t, k, n)-threshold preview-able essential secret image sharing. This research contributes to the advancement of secure and fault-tolerant secret image sharing techniques, alleviating the challenges associated with an insufficient number of essential shadows for image recovery.
Protein-ligand binding affinity prediction: Is 3D binding pose needed?
Authors: Zhi Degui , Wu Ming Hsiu , Xie Ziqian 
Published: May 2024

Abstract

Accurate protein-ligand binding affinity prediction is crucial in drug discovery. Existing methods are predominately docking-free, without explicitly considering atom-level interaction between proteins and ligands in scenarios where crystallized protein-ligand binding conformations are unavailable. Now, with breakthroughs
in deep learning AI-based protein folding and binding conformation prediction, can we improve binding affinity prediction? This study introduces a framework,
Folding-Docking-Affinity (FDA), which folds proteins, determines protein-ligand binding conformations and predicts binding affinities from three-dimensional
protein-ligand binding structures. Our experiments demonstrate that the FDA outperforms state-of-the-art docking-free models in the DAVIS dataset, showcasing
the potential of explicit modeling of three-dimensional binding conformations for enhancing binding affinity prediction accuracy.