bluuebunny/crossref_metadata_2025_split huggingface dataset:
Activation syndrome caused by paroxetine in patients with dementia with Lewy bodies
Authors: KIMURA Takemi , YUUKI Seiji , KUGA Masatoshi , HAYASHIDA Hideki , FURUKAWA Hitomi , TAKAMATSU Junichi 
Published: December 2009

AbstractActivation syndrome is a severe adverse effect caused by antidepressants. It is more frequently induced by paroxetine than by other selective serotonin reuptake inhibitors. However, there have been no descriptions of demented patients with activation syndrome derived from paroxetine. Herein, we report on three cases of dementia with Lewy bodies who suffered from activation syndrome induced by paroxetine. These symptoms rapidly disappeared following discontinuation of paroxetine. The present cases lead us to speculate that paroxetine is injurious to patients with dementia with Lewy bodies.
Edge‐roundness of boulders of Torridonian Sandstone (northwest Scotland): applications for relative dating and implications for warm and cold climate weathering rates
Authors: KIRKBRIDE MARTIN P. , BELL CARA M. 
Published: December 2009

Kirkbride, M.P. & Bell, C.M. 2009: Edge‐roundness of boulders of Torridonian Sandstone (northwest Scotland): applications for relative dating and implications for warm and cold climate weathering rates. Boreas, 10.1111/j. 1502‐3885.2009.00131.x. ISSN 0300‐9483.The relative ages of late Quaternary morainic and rock avalanche deposits on Late Precambrian Torridonian Sandstone are determined from the characteristic edge‐roundness of constituent boulders. Because weathering of sandstone is manifest as edge‐rounding by granular disintegration, a relative chronology can be derived by measuring the effective radii of curvature of a sample of boulder edges. Thirteen samples totalling 597 individual boulder edges fall into two statistically distinct groups. Moraines of inferred Younger Dryas age (12.9–11.5 kyr BP) are distinguished from moraines of the Wester Ross Re‐advance (≤14.0 kyr BP). One moraine previously assumed to be of Younger Dryas age is reassigned to the older group. The method allows spatial extrapolation of deposit ages from dated sites where lithological and sampling criteria are met. Calculated rates of edge‐rounding imply that granular disintegration was several times more rapid during cold stadial climates than during the Holocene. Used as a proxy for boulder ‘erosion rate’, this indicates that surface loss of grains in glacial climates exceeds that during interglacials by a factor of 2–5, with implications for the calculation of exposure ages from cosmogenic nuclides.
Alginate‐encapsulated HepG2 Cells in a Fluidized Bed Bioreactor Maintain Function in Human Liver Failure Plasma
Authors: Coward Sam M. , Legallais Cécile , David Bertrand , Thomas Michael , Foo Ying , Mavri‐Damelin Demetra , Hodgson Humphrey J. , Selden Clare 
Published: December 2009

AbstractAlginate‐encapsulated HepG2 cells cultured in microgravity have the potential to serve as the cellular component of a bioartificial liver. This study investigates their performance in normal and liver failure (LF) human plasma over 6–8 h in a fluidized bed bioreactor. After 8 days of microgravity culture, beads containing 1.5 × 109 cells were perfused for up to 8 h at 48 mL/min with 300 mL of plasma. After exposure to 90% LF plasma, vital dye staining showed maintained cell viability, while a 7% increase in lactate dehydrogenase activity indicated minimal cell damage. Glucose consumption, lactate production, and a 4.3‐fold linear increase in alpha‐fetoprotein levels were observed. Detoxificatory function was demonstrated by quantification of bilirubin conjugation, urea synthesis, and Cyp450 1A activity. These data show that in LF plasma, alginate‐encapsulated HepG2 cells can maintain viability, and metabolic, synthetic, and detoxificatory activities, indicating that the system can be scaled‐up to form the biological component of a bioartificial liver.
Alternative Pretreatment Modalities with a Self‐Adhesive System to Promote Dentin/Alloy Shear Bond Strength
Authors: El‐Guindy Jylan , Selim Mohamed , El‐Agroudi Mona 
Published: December 2009

Abstract Purpose: The aim of this study was to evaluate alternative pretreatment modalities to enhance the dentin/alloy shear bond strength using a self‐etch adhesive system. Material and Methods: Ninety discs were fabricated and divided into three groups (n = 30). The discs of the first group were cast in gold palladium (Au‐Pd); those of the second group were cast in palladium silver alloy (Pd‐Ag); the discs of third group were cast in nickel chromium alloy (Ni‐Cr). Each group was further divided into three subgroups (n = 10) according to the dentin pretreatment used to lute the discs. Subgroup U (no pre‐treatment): Rely X Unicem resin cement. Subgroup GU: G‐Bond then Rely X Unicem. Subgroup ZU: Zinc‐Zeolite pretreatment then Rely X Unicem. Shear bond strength was determined using a compressive mode of force applied at the dentin/alloy interface using a monobevelled chisel‐shaped metallic rod. Data were collected and statistically analyzed to assess the effect of alloy type, pretreatment modality, and their interactions on the shear bond strength. Scanning electron microscopic examination (1000×) at the dentin/resin interface was performed. Two‐way ANOVA was used in testing significance for the effect of pretreatment, alloy, and their interaction. Duncan's post hoc test was used for pairwise comparison between the means when the ANOVA test was significant. The significance level was set at p≤ 0.05. Statistical analysis was performed with SPSS 15.0®. Results: Regarding the pretreatment modality, the mean shear bond strength and 95% CI of subgroups ZU (18.00 MPa; 16.8 to 19.2) and GU (16.91 MPa; 15.4 to 18.4) were significantly higher than subgroup U (12.81 MPa; 11.4 to 14.2). Regarding the alloy type, the mean shear bond strength and 95% CI of Ni‐Cr groups (18.39 MPa; 16.9 to 19.9) were significantly higher than Au‐Pd (15.33 MPa; 13.8 to 16.8) and Pd‐Ag (13.99 MPa; 12.3 to 15.7). Conclusions: Pretreatment of dentin with G‐Bond and Zinc Zeolite improved the dentin/alloy shear bond strength. Base metal alloys provided superior bond strength values with any adhesive modality compared to noble alloys. Treatment of the dentin surface prior to the application of a self‐adhesive system is of great importance to enhancement of the dentin/alloy bond strength.
Implant‐Supported Obturator Overdenture for Extensive Maxillary Resection Patient: A Clinical Report
Authors: Leles Cláudio Rodrigues , Leles José Luiz Rodrigues , Souza Carlos de Paula , Martins Rafael Ragonezi , Mendonça Elismauro Francisco 
Published: December 2009

AbstractThis clinical report presents an implant‐retained obturator overdenture solution for a Prosthodontic Diagnostic Index Class IV maxillectomy patient with a large oronasal communication and severe facial asymmetry, loss of upper lip and midfacial support, severe impairment of mastication, deglutition, phonetics, and speech intelligibility. Due to insufficient bone support to provide satisfactory zygomaticus implant anchorage, conventional implants were placed in the body of the left zygomatic arch and in the right maxillary tuberosity. Using a modified impression technique, a cobalt‐chromium alloy framework with three overdenture attachments was constructed to retain a complete maxillary obturator. Patient‐reported functional and quality of life measure outcomes were dramatically improved after treatment and at the two‐year follow‐up.
Career Persistence in Baccalaureate‐Prepared Acute Care Nurses
Authors: Hodges Helen F. , Troyan Patricia J. , Keeley Ann C. 
Published: December 2009

Abstract Purpose: To explain how baccalaureate‐prepared acute care nurses understand, adapt to, and negotiate challenge and change in acute care settings in the context of social and structural features and consequently develop career persistence there. Design: Grounded theory method based on the research of Strauss and Corbin. Methods: A research team conducted open‐ended interviews with a theoretic sample of 19 new and experienced baccalaureate‐prepared (BSN) nurses in the southeast United States during 2007 and 2008 until saturation was achieved. Interviews were audiotaped and transcribed verbatim. Constant comparative method was used to analyze data to three increasingly abstract levels culminating in theory emergence. A diagram was developed to better understand relationships and processes. Findings: A central category, building professional resilience, emerged as the central social process with three core processes of verifying fit, stage setting, and optimizing the environment contributing to career persistence in acute care. Core processes include skills and practices nurses have learned to negotiate changing acute care environments while sustaining patient advocacy. Definitions, properties, and dimensions of each were established. Conclusions: The study offers a systematic framework for understanding and promoting career persistence for acute care nurses. Findings broaden theories of resilience to the unique settings of acute care nursing and further extend theoretical understanding of the nursing shortage and market issues of supply and demand. Clinical Relevance: A middle range theory of professional resilience and career persistence makes visible skills and practices acute‐care nurses use to weather continuous change and challenge in health care. Teachable practices can be integrated into nursing education and staff development to improve professional career longevity of experienced nurses at the bedside.
A Comparative Study of Sleep Quality Between Pregnant and Nonpregnant Taiwanese Women
Authors: Ko Shu‐Hua , Chang Shu‐Chen , Chen Chung‐Hey 
Published: December 2009

Abstract Purpose: This study explored (a) differences in sleep quality, depression, and stress among second‐ and third‐trimester pregnant and nonpregnant women, and (b) relationships among depression, stress, and sleep quality of pregnant women in Taiwan. Design: Cross‐sectional. Methods: A convenience sample of 150 second‐trimester and 150 third‐trimester pregnant women was recruited from two medical centers in Taiwan. A comparison group of 300 nonpregnant women was recruited by the acquaintance technique. Data were collected from October 2006 to September 2007 using a demographic form, Pittsburgh Sleep Quality Index (PSQI), Edinburgh Postnatal Depression Scale, and Perceived Stress Scale. Findings: The prevalence of poor sleepers (PSQI score>5) was 60.0% for second‐ and third‐trimester pregnant women and 48.0% for nonpregnant women. After controlling for significant covariates, pregnant women reported worse global sleep quality, habitual sleep efficiency, and sleep disturbances than nonpregnant women, and poorer sleep quality and sleep latency were most prevalent during their third trimester. A high prevalence of antenatal depression (27.3% to 36.0%) was found in pregnant women, depressed women had worse sleep quality than nondepressed women in all groups, and stress affected sleep quality in pregnant women but not in nonpregnant women. Conclusions: This cross‐sectional study provides preliminary evidence that pregnant women suffer significantly more poor sleep quality than nonpregnant women, and that sleep quality of pregnant women was related to stress and depression. Clinical Relevance: Evaluation for sleep quality and depression should be part of routine prenatal check‐ups. Information on women's sleep quality, stress, and depressive status can be used to individualize interventions for pregnancy‐associated sleep disorder.
Conceptualization and Measurement of Coping During Adolescence: A Review of the Literature
Authors: Garcia Carolyn 
Published: December 2009

AbstractPurpose:The purpose of this review was to examine the conceptualization and measurement of coping in adolescent research.Design:A review of the literature published and abstracted in four scientific databases was undertaken between July 2008 and June 2009 with the following key words: adolescent(s), cope/coping, stress(ors), and adaptation/psychological.Methods:A total of 367 articles were initially identified, and review of published abstracts yielded 104 empirical articles to retrieve and examine more closely for inclusion. Criteria for inclusion in the review were that the study (a) measured coping, (b) presented original data, (c) primarily targeted adolescent participants, (d) was reported in English, and (e) was published between 1998 and June 2009. Fifty‐nine subsequent articles were organized using a matrix approach that facilitated cross‐study comparisons of purpose, sample, and dependent variables.Findings:Fewer than half of the studies reviewed included a specific statement defining coping. Instead, many authors described coping in the context of stress response by identifying particular types or ways of coping or naming specific coping strategies used. The theoretical frameworks guiding examination of coping varied across studies. A range of measures, congruent with adolescent developmental processes, were used to assess adolescent coping. A wide range of stress‐related risks or conditions were examined, including psychological stressors such as eating disorders, suicidal ideation, and depression; physical stressors such as chronic illness, HIV infection, sports participation, violence, or sexual abuse; familial stressors such as domestic violence or interparental conflict; social stressors such as romantic relationships or difficulties in settings such as school, prison, or a homeless shelter; and societal stressors such as discrimination.Conclusions:Coping is an important construct in understanding how adolescents react to the extensive stressors and adjustments they experience. Coping is a complex construct yet worthy of examination because it can be a critical point of intervention in the health trajectory of adolescents and young people. Research is needed to advance the conceptualization and measurement of adolescent coping such that interpretation of findings across studies is enhanced. In this way, future research, including interventions targeting coping, will work synergistically to advance the science and adolescent well‐being.Clinical Relevance:Nursing and other healthcare providers working with adolescents understand the need for interventions that promote use of healthy coping strategies and minimize unhealthy coping. Findings from this study demonstrate the state of coping conceptualization and measurement in adolescent research and indicate a need for research that will advance the science and improve the usefulness of adolescent coping data.
Initial pattern of angiogenesis and bone formation following lateral ridge augmentation using rhPDGF and guided bone regeneration: an immunohistochemical study in dogs
Authors: Schwarz Frank , Ferrari Daniel , Podolsky Laura , Mihatovic Ilja , Becker Jürgen 
Published: December 2009

AbstractObjectives: To evaluate (i) the effects of rhPDGF‐BB on localized ridge augmentation using a natural bone mineral (NBM), and (ii) the influence of a collagen membrane (CM) on factor activity.Materials and methods: Chronic‐type alveolar ridge defects (n=4 dogs) were randomly allocated in a split‐mouth design as follows: upper jaw: NBM+rhPDGF‐BB+CM (test) vs. NBM+rhPDGF‐BB (control), and lower jaw: NBM+rhPDGF‐BB+CM (test) vs. NBM+CM (control). After 3 weeks, dissected blocks were prepared for immunohistochemical (angiogenesis – TG) and histomorphometrical analysis [e.g. augmented area (AA), mineralized – (MT), non‐mineralized tissue (NMT) (mm2)].Results: Lower jaw: TG and mineralization of AA mainly originated from the defect borders. Test sites revealed a pronounced TG antigen reactivity and higher AA and MT values (mean and median). Upper jaw: control sites revealed a dislocation of AA in caudal direction, but also an improved vascularization in the peripheral wound area. While MT values (median) appeared to be comparable in both groups, AA, NMT, and NBM values (mean and median) tended to be higher at test sites.Conclusions: It was concluded that (i) rhPDGF‐BB soak‐loaded on NBM might have the potential to support bone formation at chronic‐type lateral ridge defects, and (ii) the application of CM did not seem to interfere with the factor activity, but ensured a stabilization of the graft particles. To cited this article:
Schwarz F, Ferrari D, Podolsky L, Mihatovic I, Becker J. Initial pattern of angiogenesis and bone formation following lateral ridge augmentation using rhPDGF and guided bone regeneration: an immunohistochemical study in dogs. Clin. Oral Impl. Res. 21, 2010; 90–99.
Platform switching and marginal bone‐level alterations: the results of a randomized‐controlled trial
Authors: Canullo Luigi , Fedele Giampiero Rossi , Iannello Giuliano , Jepsen Søren 
Published: December 2009

AbstractObjectives: This randomized‐controlled trial aimed to evaluate marginal bone level alterations at implants restored according to the platform‐switching concept, using different implant/abutment mismatching.Material and methods: Eighty implants were divided according to the platform diameter in four groups: 3.8 mm (control), 4.3 mm (test group1), 4.8 mm (test group2) and 5.5 mm (test group3), and randomly placed in the posterior maxilla of 31 patients. After 3 months, implants were connected to a 3.8‐mm‐diameter abutment and final restorations were performed. Radiographic bone height was measured by two independent examiners at the time of implant placement (baseline), and after 9, 15, 21 and 33 months.Results: After 21 months, all 80 implants were clinically osseointegrated in the 31 patients treated. A total of 69 implants were available for analysis, as 11 implants had to be excluded from the study due to early unintentional cover screw exposure. Radiographic evaluation showed a mean bone loss of 0.99 mm (SD=0.42 mm) for test group1, 0.82 mm (SD=0.36 mm) for test group2 and 0.56 mm (SD=0.31 mm) for test group3. These values were statistically significantly lower (P<0.005) compared with control (1.49 mm, SD=0.54 mm). After 33 months, five patients were lost to follow‐up. Evaluation of the remaining 60 implants showed no difference compared with 21 months data except for test group2 (0.87 mm) and test group3 (0.64 mm). There was an inverse correlation between the extent of mismatching and the amount of bone loss.Conclusions: This study suggested that marginal bone level alterations could be related to the extent of implant/abutment mismatching. Marginal bone levels were better maintained at implants restored according to the platform‐switching concept. To cite this article:
Canullo L, Fedele GR, Iannello G, Jepsen S. Platform switching and marginal bone‐level alterations: the results of a randomized‐controlled trial. Clin. Oral Impl. Res. 21, 2010; 115–121.
Analysis of the socket bone wall dimensions in the upper maxilla in relation to immediate implant placement
Authors: Huynh‐Ba Guy , Pjetursson Bjarni E. , Sanz Mariano , Cecchinato Denis , Ferrus Jorge , Lindhe Jan , Lang Niklaus P. 
Published: December 2009

AbstractBackground: Animal and human researches have shown that immediate implant placement into extraction sockets failed to prevent socket dimensional changes following tooth extraction. It has been suggested that a minimal width of 1–2 mm of buccal bone is necessary to maintain a stable vertical dimension of the alveolar crest.Aim: To determine the dimensions of the bony wall at extraction sites in the esthetic zone (anterior teeth and premolars in the maxilla) and relate it to immediate implant placement.Methods: As part of an ongoing prospective randomized‐controlled multicenter clinical study on immediate implant placement, the width of the buccal and palatal bony walls was recorded at 93 extraction sites.Results: The mean width of the buccal and palatal bony walls was 1 and 1.2 mm, respectively (P<0.05). For the anterior sites (canine to canine), the mean width of the buccal bony wall was 0.8 mm. For the posterior (premolar) sites, it was 1.1 mm (P<0.05). In the anterior sites, 87% of the buccal bony walls had a width ≤1 mm and 3% of the walls were 2 mm wide. In the posterior sites, the corresponding values were 59% and 9%, respectively.Conclusions: If the criterion of a minimal buccal bone width of 2 mm to maintain a stable buccal bony wall is valid, only a limited number of sites in the anterior maxilla display such a clinical situation. The data suggested that in the majority of extraction sites in the anterior maxilla, thin (≤1 mm) buccal walls were present. This, in turn, means that in most clinical situations encountered, augmentation procedures are needed to achieve adequate bony contours around the implant. To cite this article:
Huynh‐Ba G, Pjetursson BE, Sanz M, Cecchinato D, Ferrus J, Lindhe J, Lang NP. Analysis of the socket bone wall dimensions in the upper maxilla in relation to immediate implant placement. Clin. Oral Impl. Res. 21, 2010; 37–42.
ORIGINAL ARTICLE: Female Genital Tract Secretions Inhibit Herpes Simplex Virus Infection: Correlation with Soluble Mucosal Immune Mediators and Impact of Hormonal Contraception
Authors: Shust Gail F. , Cho Sylvia , Kim Mimi , Madan Rebecca P. , Guzman Esmeralda M. , Pollack Margaret , Epstein Julia , Cohen Hillel W. , Keller Marla J. , Herold Betsy C. 
Published: December 2009

Citation Shust GF, Cho S, Kim M, Madan RP, Guzman EM, Pollack M, Epstein J, Cohen HW, Keller MJ, Herold BC. Female genital tract secretions inhibit herpes simplex virus infection: correlation with soluble mucosal immune mediators and impact of hormonal contraception. Am J Reprod Immunol 2010; 63: 110–119Problem  Female genital tract secretions inhibit herpes simplex virus (HSV) infection, however, the intra‐ and inter‐subject variability, contribution of specific mediators, and impact of reproductive hormones have not been defined.Method of study  Cervicovaginal lavage (CVL) (n = 89) obtained from nine cyclers and seven women on hormonal contraception (HC), who completed between three and eight weekly visits, were examined for anti‐herpes simplex virus activity and concentrations of mediators.Results  The CVL inhibited HSV infection by a mean value of approximately 57% during the follicular or luteal phase, but only by 36% in hormonal contraceptive users. Human neutrophil peptides 1–3 (HNP1‐3) (P = 0.03), IL‐8 (P = 0.003), lactoferrin (P = 0.005), lysozyme (P = 0.003), IgA (P = 0.002), and IgG (P = 0.02) correlated with antiviral activity. Intra‐subject and inter‐subject variability was observed, suggesting that factors other than hormones contribute to innate defense.Conclusion  Endogenous antimicrobial activity may provide a biomarker of healthy mucosal immunity and may be reduced in the setting of HC. However, larger prospective studies are needed.