bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Not-So-Slight Perceptual Consequences of Slight Hearing Loss in School-Age Children: A Scoping Review
Authors: Patro Chhayakanta , Mishra Srikanta Kumar 
Published: May 2024

Purpose:
This study aimed to conduct a scoping review of research exploring the effects of slight hearing loss on auditory and speech perception in children.

Method:
A comprehensive search conducted in August 2023 identified a total of 402 potential articles sourced from eight prominent bibliographic databases. These articles were subjected to rigorous evaluation for inclusion criteria, specifically focusing on their reporting of speech or auditory perception using psychoacoustic tasks. The selected studies exclusively examined school-age children, encompassing those between 5 and 18 years of age. Following rigorous evaluation, 10 articles meeting these criteria were selected for inclusion in the review.

Results:
The analysis of included articles consistently shows that even slight hearing loss in school-age children significantly affects their speech and auditory perception. Notably, most of the included articles highlighted a common trend, demonstrating that perceptual deficits originating due to slight hearing loss in children are particularly observable under challenging experimental conditions and/or in cognitively demanding listening tasks. Recent evidence further underscores that the negative impacts of slight hearing loss in school-age children cannot be solely predicted by their pure-tone thresholds alone. However, there is limited evidence concerning the effect of slight hearing loss on the segregation of competing speech, which may be a better representation of listening in the classroom.

Conclusion:
This scoping review discusses the perceptual consequences of slight hearing loss in school-age children and provides insights into an array of methodological issues associated with studying perceptual skills in school-age children with slight hearing losses, offering guidance for future research endeavors.
Enhancing the biological functionality of poly (lactic‐co‐glycolic acid) cage‐like structures through surface modification with micro‐ and nano‐sized hydroxyapatite particles
Authors: Chang Dongbiao , Li Siyu , Bai Zhenfan , You Jing , Cao Lili , Li Qingcao , Tan Huan , Zheng Yan , Ye Feilun , Weng Jie 
Published: May 2024

AbstractBiomaterials with exceptional performance are crucial for addressing the challenges of complex bone regeneration. Compared with traditional three‐dimensional scaffolds, injectable microspheres enable new strategies for the treatment of irregular bone defects. Biodegradable poly (lactic‐co‐glycolic acid) has found widespread applications as microcarriers of drugs, proteins, and other active macromolecules. Applied to the surface of poly (lactic‐co‐glycolic acid) cage‐like structures (PLGA‐CAS), hydroxyapatite (HA) effectively reduces inflammation while enhancing biological effects. In this study, we loaded the surface of PLGA‐CAS with micro‐ and nano‐hydroxyapatite particles, referred to as μHA/PLGA‐CAS and nHA/PLGA‐CAS, respectively. Subsequently, their material characteristics and biological effects were assessed. The incorporation of hydroxyapatite onto PLGA‐CAS resulted in enhanced surface roughness and hydrophilicity, coupled with improved thermal stability and delayed degradation. Furthermore, μHA/PLGA‐CAS induced osteogenic differentiation of osteoblast precursor cells, while nHA/PLGA‐CAS improved endothelial cell adhesion and stimulated angiogenic differentiation in vitro. Collectively, these findings suggest that μHA/PLGA‐CAS and nHA/PLGA‐CAS, each with distinct characteristics, hold significant potential for application as microcarriers in various biomedical contexts.
Clustered DTN routing based on sensing node relationship strength
Authors: Chen Hongsheng , Wu Chunhui 
Published: May 2024

AbstractDelay tolerant networks (DTNs) is a network evolved from mobile networks. Differing from the traditional network, which has a stable end‐to‐end transmission path, DTNs are sparse and intermittently connected mobile ad hoc network, which are widely used in harsh environments, such as battlefields, seabed, space communication networks, and so on. In DTNs, intermittent connectivity, partitioned network, long delays and node mobility characteristics make the network fail to communicate frequently, therefore, how to successfully forward the message is of extreme importance. Up to now, almost all the traditional models in DTNs use the store‐carry‐forward method. This paper proposes a novel clustered DTN routing model based on sensing node relationship strength. The routing mechanism takes advantage of the number of other nodes encountered by the nodes in the process of movement and the changes in the number of nodes to calculate the strength of the relationship between nodes, and clusters DTN routing according to the strength of the relationship between nodes. Moreover, the relationship between nodes in a cluster and other clusters is used to transmit messages between clusters, and messages are transmitted within clusters according to the strength of the relationship between nodes. Simulation results show that the routing mechanism not only increases the success rate of message transmission, but also reduces the transmission delay of messages and improves network performance.
ER‐Mapping: An extrinsic robust coloured mapping system using residual evaluation and selection
Authors: Jiang Changjian , Wan Zeyu , Gao Ruilan , Zhang Yu 
Published: May 2024

AbstractThe colour‐enhanced point cloud map is increasingly being employed in fields such as robotics, 3D reconstruction and virtual reality. The authors propose ER‐Mapping (Extrinsic Robust coloured Mapping system using residual evaluation and selection). ER‐Mapping consists of two components: the simultaneous localisation and mapping (SLAM) subsystem and the colouring subsystem. The SLAM subsystem reconstructs the geometric structure, where it employs a dynamic threshold‐based residual selection in LiDAR‐inertial odometry to improve mapping accuracy. On the other hand, the colouring subsystem focuses on recovering texture information from input images and innovatively utilises 3D–2D feature selection and optimisation methods, eliminating the need for strict hardware time synchronisation and highly accurate extrinsic parameters. Experiments were conducted in both indoor and outdoor environments. The results demonstrate that our system can enhance accuracy, reduce computational costs and achieve extrinsic robustness.
Smart resilience through IoT‐enabled natural disaster management: A COVID‐19 response in São Paulo state
Authors: Santos Alessandro S. , Goncales Icaro , Silva Angelina , Neves Rodrigo , Teixeira Igor , Barbosa Eder , Gava Vagner , Yoshida Olga 
Published: May 2024

AbstractNatural disaster management approach establishes stages of prevention, preparation, response, and recovery. With the Internet of Things (IoT), Bigdata, Business Intelligence, and other Information Communication Technologies, data can be gathered to support decisions in stages of the response to natural disaster events. In biological natural disasters, the ICTs can also support efforts to promote social distancing, public health, and economic monitoring to face the threads. São Paulo state used IoT in scenarios to face COVID‐19, such as monitoring vehicular interurban mobility, social distancing, and economic activity. Frameworks, strategies, data views, and use cases are presented to support the decision‐making process to face this biological natural disaster. The data‐driven approach supports several purposes, including the communication of social distancing indices, economic recovery, the progression of contagion, and deaths. It also played a pivotal role in fostering transparency initiatives for society and supporting the crisis committee by facilitating situational analyses, and this approach became standard practice for pandemic response. Studies and innovative visualisation perspectives have produced positive outcomes, guiding the decision‐making process through data analysis. Noteworthy use cases were interurban traffic fence monitoring; mapping of virus spreading; tracking the economic impact concerning recovery plans; and, evaluating the effectiveness of public policies.
Rotation periods of asteroids from light curves of TESS data
Authors: Vavilov D. E. , Carry B. 
Published: May 2024

Context. Understanding the dynamical evolution of asteroids through the secular Yarkovsky effect requires the determination of many physical properties, including the rotation period.
Aims. We propose a method aimed at obtaining a robust determination of the rotation period of asteroids, while avoiding the pitfalls of aliases. We applied this approach to thousands of asteroid light curves measured by the NASA TESS mission.
Methods. We developed a robust period-analysis algorithm based on a Fourier series. Our approach includes a comparison of the results from multiple orders and tests on the number of extremes to identify and reject potential aliases. We also provide the uncertainty interval for the result as well as additional periods that may be plausible.
Results. We report the rotation period for 4521 asteroids within a precision of 10%. A comparison with the literature (whenever available) reveals a very good agreement and validates the approach presented here. Our approach also highlights cases for which the determination of the period should be considered invalid. The dataset presented here confirms the apparent small number of asteroids with a rotation between 50 and 100 h and correlated with diameter. The amplitude of the light curves is found to increase toward smaller diameters, as asteroids become less and less spherical. Finally, there is a systematic difference between the broad C and S complex in the amplitude-period, revealing the statistically lower density of C-types compared to S-type asteroids.
Conclusions. Our approach to the determination of asteroid rotation period is based on simple concepts, yet it is nonetheless robust. It can be applied to large corpora of time series photometry, such as those extracted from exoplanet transit surveys.
Genetische Testung bei Kardiomyopathien: ein Update für die Praxis
Authors: Trenkwalder Teresa , Knoll Katharina , Schunkert Heribert 
Published: May 2024

ZusammenfassungDie rasante Verbesserung der DNA-Sequenzierung hat die genetische Diagnostik als zentrale Säule in der ätiologischen Abklärung von Kardiomyopathien etabliert. Neben der Diagnosesicherung kann so bei manchen Kardiomyopathien auch eine individuelle Risikobewertung und Differenzialtherapie möglich werden. Darüber hinaus ist die genetische Diagnostik von zentraler Bedeutung für die Untersuchung weiterer Familienmitglieder. Für eine effektive Nutzung dieser Technologie ist eine sorgfältige Abwägung der Indikationen, eine genaue Auswahl der zu testenden Gene und eine fundierte Interpretation der Ergebnisse entscheidend.
DGN-Handlungsempfehlung (S1-Leitlinie) – Version 3
Authors: Schmidt M. , Hohberg M. , Felcht M. , Kühn T. , Eichbaum M. , Krause B. J. , Zöphel B. K. , Kotzerke J. ,   Deutsche Dermatologische Gesellschaft (DDG), vertreten durch,   Prof. Dr. M. Felcht (Klinik für Dermatologie, Venerologie und Allergologie, Universitätsmedizin Mannheim),   Deutsche Gesellschaft für Gynäkologie und Geburtshilfe (DGGG), vertreten durch,   Prof. Dr. T. Kühn (Klinik für Frauenheilkunde und Geburtshilfe, Klinikum Esslingen) und,   Prof. Dr. M. Eichbaum (Klinik für Gynäkologie und gynäkologische Onkologie, Helios Dr.-Horst-Schmidt-Kliniken Wiesbaden)
Published: May 2024

Die Autoren veröffentlichen eine Verfahrensanweisung zur szintigrafischen Lokalisation von Wächterlymphknoten beim malignen Melanom, beim Mammakarzinom, beim Penis- und Vulvakarzinom sowie bei Kopf-Hals-Tumoren und beim Prostatakarzinom. Wesentliche Ziele der szintigrafischen Wächterlymphknotendiagnostik bestehen in der Minimierung des Operationsausmaßes und der postoperativen Morbidität sowie der Optimierung der histopathologischen Aufarbeitung durch Fokussierung auf die relevanten Lymphknoten. Die Wächterlymphknotenszintigrafie trifft selbst keine Aussage zu einem evtl. tumorösen Befall und ist nicht indiziert, wenn bereits eine lymphogene (Ausnahme Prostata-Ca) oder Fernmetastasierung diagnostiziert ist. Es werden Vorgehensweisen zur Durchführung zusammengestellt, die zum Ziel haben, den oder die Wächterlymphknoten zuverlässig und mit hoher Nachweisrate typischerweise in einem frühen Stadium einer Tumorerkrankung zu detektieren. Neue Aspekte in dieser überarbeiteten Leitlinie sind neue Radiopharmaka wie Tilmanocept und Tc-99m-PSMA sowie die SPECT/CT, die besonders bei Genitaltumoren und im Kopf-Hals-Bereich die anatomische Orientierung erleichtert. Abgewertet wird die Bedeutung der initialen dynamischen Lymphszintigrafie beim Mammakarzinom. Die Strahlenexposition des Patienten/der Patientin ist so niedrig, dass Schwangerschaft keine grundsätzliche Kontraindikation darstellt. Bei Schwangerschaft wird bevorzugt ein 1-Tages-Protokoll eingesetzt. Aufgrund der sehr geringen Strahlenexposition von < 1 mSv/Jahr müssen auch Operateur, OP-Personal und Pathologe selbst bei häufiger Durchführung der Sentinel-Lymphonodektomie (SLNE) nicht als beruflich strahlenexponierte Personen geführt werden. Aspekte der Qualitätssicherung wurden neu aufgenommen (Szintigramm, Überprüfung der Messsonde, 6 h SLN-Kurs für Operateure, zertifizierte Brustzentren, Überprüfung durch die Ärztlichen Stellen).
Is Immediate Postoperative Radiograph Necessary Following Robotic-Assisted Total Knee Arthroplasty?
Authors: Giordano Joshua R. , Bartlett Lucas , Huyke Fernando , Sadh Puru , Thompson Kiara , Ajah Obinnah , Danoff Jonathan 
Published: May 2024

AbstractThe necessity of immediate postoperative radiographs following total knee arthroplasty (TKA) has long been debated. With the increasing use of robotic-assisted TKA (RTKA), and thus more precise implant placement, the need for immediate postoperative radiographs to determine implant positioning may be unnecessary. We sought to evaluate implant position on the immediate postoperative radiographs following RTKA to determine their necessity. A retrospective review of 150 RTKAs was performed. The posterior slopes for all TKAs were recorded based on the preoperative three-dimensional template. Additionally, two independent trained researchers (J.G./L.B.) each measured the posterior slope of the postoperative day 0 (POD0) radiograph and postoperative week 2 radiograph. The difference in posterior slope measurement between template and POD0, between template and postoperative week 2, and between POD0 and postoperative week 2 was calculated. Of the 150 TKAs performed, there were no periprosthetic fractures found on the POD0 radiograph. The mean difference between the templated posterior slope and measured posterior slope on POD0 was 0.04 degrees (standard deviation [SD], 1.01; p = 0.615). There was a weak correlation between the two values (rs
[95% confidence interval (CI)], 0.38 [0.21, 0.53]). When comparing the template to the postoperative week 2 radiographs, there was a mean difference of 0.02 degrees (SD, 0.48; p = 0.556).  However, a moderate to strong correlation was noted (rs
[95% CI], 0.71 [0.61, 0.79]). Comparison of the mean posterior slope from POD0 radiograph to that of postoperative week 2 radiograph showed a mean difference of 0.06 degrees (SD, 1.0; p = 0.427). A weak correlation was found between these two values (rs
[95% CI], 0.43 [0.26, 0.56]). Given the accuracy and precision of RTKA, along with the ability to decrease cost and radiation, immediate postoperative radiograph may be unnecessary, when pertaining to the uncomplicated RTKA. However, if there is concern for intraoperative fracture, long stems placed in a revision arthroplasty, or other intraoperative complications, then postoperative radiographs are encouraged.
Docetaxel, Oxaliplatin with Capecitabine (TEX Regimen) in Metastatic Gastric and Gastroesophageal Adenocarcinoma: A Prospective Single-Arm Observational Study from a Tertiary Cancer Center in Kashmir
Authors: Puthiyottil Sanudev Sadanandan Vadakke , Guru Faisal R. , Ahmad Syed Nisar , Wahid Mir Ab , Ahmad Choh Naseer , Maqbool Lone Mohammad , Mir Mohammad Hussain , Zaffar Banday Saquib , Kunju Hashim Ismail , Muhammed Bhat Gul 
Published: May 2024

Abstract
Background Metastatic gastric and gastroesophageal adenocarcinoma (MGGEAC) is a challenging disease with limited treatment options. The Taxotere, Eloxatin, and Xeloda (TEX) regimen has shown promising results in several clinical trials. There exists a dearth of data pertaining to the efficacy and tolerance of the treatment approach in the populace of Kashmir.
Methods This study was performed at the Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir. Patients with MGGEAC received treatment with biweekly TEX regimen that included docetaxel 50 mg/m2-D1, oxaliplatin 85 mg/m2-D1, and capecitabine 1250 mg/m2/day, twice daily orally, for 14 days. The effectiveness of the regimen was assessed based on the overall response rate (ORR), progression-free survival (PFS), and overall survival (OS), along with the prognostic factors, safety, and tolerability of the regimen.
Results The ORR was 63.5% after four cycles. The median PFS and OS were 9.1 and 13 months, respectively. Univariate and multivariate analysis showed that a higher number of sites of metastases is associated with poor PFS. The TEX regimen was well tolerated. The most observed grade 3 to 4 toxicities were neutropenia (36.7%), anemia (20%), fatigue (20%), and febrile neutropenia (16.7%).
Conclusion Using the TEX regimen in MGGEAC showed better response rates and a slightly longer PFS. A higher number of sites of metastases is a poor prognostic factor in MGGEAC, as seen in our study. The toxicity profile shows that the regimen is tolerable. We recommend a randomized controlled study comparing CapeOx with TEX to test this regimen further.
Balancing Risks versus Benefits: Vitamin C Therapy versus Copper Oxide Nanoparticles Toxicity in Albino Rats' Submandibular Salivary Gland
Authors: Shamel Mohamed , Baz Safaa , Mahmoud Heba , Taghyan Salma Awad , Bakr Mahmoud M. , Al Ankily Mahmoud 
Published: May 2024

Objectives This study aimed to examine the suppressive effect of the natural antioxidant vitamin C (VC) against submandibular gland toxicity induced by copper oxide nanoparticles (CuO-NPs).
Materials and Methods Three groups of 30 mature male albino rats (4 weeks old) weighing between 150 and 200 g were selected. The rats were randomly assigned for 6 weeks to receive: intraperitoneal injection (IP) of vehicle (control group); IP of 2.5 mg/kg body weight (bw) of CuO-NPs (CuO-NPs group); and IP of 2.5 mg/kg bw of CuO-NPs, combined with a daily oral dose of 100 mg/kg bw of VC in drinking water via gavage (CuO-NPs/VC group). The rats were euthanized, and their submandibular glands were dissected for histological evaluation, including hematoxylin and eosin staining and immunohistochemistry for Ki-67 and caspase-3.
Statistical Analysis The area expression for Ki-67 and caspase-3 was statistically analyzed using GraphPad Prism. Following analysis of variance analysis, Tukey's post hoc was used for multiple comparisons. The significance level was set at p < 0.05.
Results CuO-NPs caused significant cytotoxic effects on submandibular salivary gland cells in albino rats. This led to an increase in Ki-67 and caspase-3 levels compared with the control group. VC administration improved tissue histology and reduced Ki-67 and caspase-3 levels in the VC/CuO-NPs group compared with rats treated with CuO-NPs alone.
Conclusion The study revealed significant cytotoxic effects of CuO-NPs on the submandibular salivary gland of albino rats. VC effectively mitigated these toxic effects, suggesting its potential as a readily available antioxidant.
Evaluation of the Impact of Irradiance Lamps and Storage Media on Elution of TEGDMA from Dental Composites
Authors: Tauseef Kiran , Amin Faiza , Moin Syed Faraz , Khurshid Zohaib , Aslam Kashif , Jabeen Bushra 
Published: May 2024

Abstract
Objectives The aim of this study was to evaluate and compare the effect of irradiance light and storage media on the elution of triethylene glycol dimethacrylate (TEGDMA) from conventional Filtek Z350XT 3M ESPE and two bulk-fill composites Shofu Beautifil-Bulk and Filtek Bulk fill flowable 3M ESPE using high-performance liquid chromatography (HPLC).
Materials and Methods Shofu Beautifil-Bulk, Filtek Bulk fill flowable 3M ESPE, and Filtek Z350XT 3M ESPE were the three types of composites used in this study. Disk shaped samples of 4-mm thickness and 10-mm diameter were fabricated using a stainless steel mold and were polymerized using light emitting diode (LED) and quartz tungsten halogen (QTH) lamps. After polymerization, the samples were immersed in ethanol, artificial saliva with betel quid extract, and distilled water for 1, 7, and 30 days, respectively. The elution of monomer TEGDMA was evaluated using HPLC.
Statistical Analysis To evaluate the mean concentration difference, mixed way analysis of variance (ANOVA) was applied. Between different light, materials, and within the time duration, Tukey's post hoc test was used. A p value of 0.05 was considered significant.
Results During the first day of storage, a significant amount of monomer TEGDMA elution was seen in all the materials. The highest values observed to be in the disks cured with QTH lamp. However, the highest elution was seen when the disks were immersed in ethanol/water solution. While the most stable medium was distilled water, artificial saliva with betel nut extract also had a significant effect on the elution of TEGDMA. The highest value obtained was of Filtek Bulk fill flowable 3M ESPE after 30 days of immersion in both LED and QTH cured disks.
Conclusion Filtek Bulk fill flowable 3M ESPE shows better properties in relation to the release of monomer TEGDMA as it releases less amount of monomer in the storage media. The release of monomer was highest in ethanol as compared to artificial saliva and distilled water with the passage of time.
Late Manipulation under Anesthesia after Total Knee Arthroplasty: Improved Range of Motion and a Low Complication Rate
Authors: Weintraub Matthew T. , Kurina Steven J. , Cline Joseph T. , Forlenza Enrico M. , Berger Richard A. , Gerlinger Tad L. 
Published: May 2024

AbstractThe purpose of this study was to evaluate outcomes of late manipulation under anesthesia (MUA) for stiffness performed from ≥12 weeks to more than a year after primary total knee arthroplasty (TKA). A total of 152 patients receiving MUA ≥12 weeks after primary TKA from 2014 to 2021 were reviewed. The primary outcome measured was change in range of motion (ROM). We tracked intraoperative complications and the need for repeat MUA or open procedure for continued stiffness after initial MUA. Three subgroups were analyzed: Group 1 included 58 knees between 12 weeks and 6 months after TKA, Group 2 included 44 knees between 6 and 12 months after TKA, and Group 3 included 50 knees ≥12 months after TKA. Analysis included descriptive statistics and univariate analysis, with α <0.05. Groups 1 to 3 all significantly increased their overall ROM by 20.9, 19.2, and 22.0 degrees, respectively. All groups significantly increased their flexion and extension from preoperatively. Group 1 had one intraoperative supracondylar femur fracture (1.7%) requiring open reduction and internal fixation, and five patients required repeat MUA or open procedure (8.6%). Group 2 had no intraoperative fractures, and five patients required repeat MUA or open procedure (11.4%). Group 3 had one intraoperative tibial tubercle avulsion fracture managed conservatively (2.0%) and one repeat MUA (2.0%). Late MUA resulted in significantly improved ROM in all groups. ROM improved more as the time from index TKA increased, although statistically insignificant. Repeat MUA or open procedure rate decreased with MUA ≥12 months from TKA, although statistically insignificant. The overall intraoperative fracture risk was 1.3%.