bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shear wave elastography of the supraspinatus tendon with early degeneration in asymptomatic type II diabetes mellitus patients: a multicenter study
Authors: Wang Tong , He Yanni , Yi Wenhong , Xie Huiyu , Wang Dan , Zeng Jie , Liang Jinying , Chen Yufan , Mo Qiuyan , Zhou Meijun , Li Sushu , Huang Feifei , Liu Shaoming , Ma Liya , Liu Xueling , Liu Hongmei 
Published: June 2024

Abstract

Objectives This study aimed to explore conventional ultrasound sonography and shear wave elastography (SWE) changes in the supraspinatus tendon in type 2 diabetes patients (T2DM) without shoulder pain. The factors influencing supraspinatus tendon thickness and shear wave velocity (SWV), which are measured by SWE, were also explored.
Methods This multicenter study recruited nonshoulder pain individuals, including healthy and diabetic patients from March 2021 to October 2022. Propensity score matching was used to overcome selection bias. The thickness and SWV of the bilateral supraspinatus tendons were measured, and their influencing factors were evaluated via regression analysis. The sonography and blood flow signals were observed and compared via χ2 tests.
Results A total of 107 T2DM patients and 270 healthy people were enrolled (mean age, 42 years +/- 14, 162 men). Although 59.8% of T2DM patients without shoulder pain, they were likely to have degenerative ultrasonic image and a lower SWV (-0.529 [-0.827, -0.232] vs. 1; p = 0.001) than healthy people, but no difference was detected for uneven thickening of the tendon (p = 0.055) or blood flow signals (p = 0.060).
Furthermore, subjects > 50 years old, with a BMI ≥ 25.0 and who were of Zhuang nationality had thicker supraspinatus tendons than did the controls. Han individuals and regular upper limb exercise subjects had greater tendon SWV than did controls.
Conclusions SWE is a repeatable and early tool for assessing supraspinatus tendon degeneration in asymptomatic patients with T2DM. Active control of the condition of diabetes patients and regular upper limb exercise might help delay the degeneration of supraspinatus tendons.
Comparison of Low-Pressure and Standard-Pressure Pneumoperitoneum Laparoscopic Cholecystectomy in Patients with Cardiopulmonary Comorbidities: A Double Blinded Randomized Clinical Trial
Authors: Tian Feng , Sun Xiaowei , Yu Yang , Zhang Ning , Hong Tao , Liang Lu , Yao Bihui , Song Lei , Pei Changhong , Wang Yu , Lu Wenlong , Qu Qiang , Guo Junchao , Zhang Taiping , He Xiaodong 
Published: June 2024

Abstract

Background
The safety and efficacy of low-pressure laparoscopic cholecystectomy (LPLC) in patients with cardiopulmonary comorbidities remain unclear.
Methods
This was a multicenter, parallel, double-blind, randomized controlled trial performed from January 1, 2019, to January 31, 2023. Eligible patients included patients with cardiac or pulmonary comorbidities, who were randomly assigned (1:1) to undergo LPLC (10 mmHg) or standard-pressure laparoscopic cholecystectomy (SPLC) (14 mmHg). The primary outcome was intraoperative surgeon comfort. Surgical safety variables, patient recovery, and pulmonary function parameters were also compared between groups.
Results
This study enrolled 144 participants, with 124 participants extracted for the final analysis (62 in LPLC and 62 in SPLC group, respectively). Similar proportion of surgeons reported excellent working space and surgical view (90.3% in the LPLC and 98.4% in the SPLC groups, respectively, p = 0.114). There was no between-group difference regarding intraabdominal operative time, rate of intraoperative bile spillage, blood loss, and conversion rate. Moreover, postoperative major complication rates, the median time to the first flatus, postoperative hospital stay, or mean postoperative visual analog scale score for pain were similar in both groups. Pulmonary parameters including postoperative pH, PaCO2, HCO3, and lactate levels were similar between the two comparing groups.
Conclusions
LPLC with a pneumoperitoneum pressure of 10 mmHg is safe and reasonable for patients with cardiopulmonary comorbidities.
Registration:
The trial is registered at ClinicalTrials.gov (NCT04670952).
The Model of Digital Pedagogies and Digital Quality Management in practically oriented Higher Education Institutions (HEIs). The case of Laurea University of Applied Sciences.
Authors: Ulatowska Roksana , Sułkowski Łukasz , Bilan Svitlana 
Published: June 2024

Abstract

The Industrial Revolution 4.0 and the ongoing development of technology result in a digital transformation which forces higher education institutions (HEIs) to introduce significant changes. These changes necessitate a new approach that encompasses not only learning methodologies but also the university’s culture, strategy, and systemic activities. In this article we present a new, unique model of Digital Pedagogies and Digital Quality Management exemplified by the case applied approach. The model shows the intersection of the‘Digital learning foundation’,‘ Enabling factors’(digital flexibility and digital learning tools),‘Systematic quality of learning management’ and ‘Challenges of Digital Flexibility’ in HEIs. The proposed model applies practices and recommendations for Universities of Applied Sciences, making it worth disseminating in this context. The model can be useful and beneficial for facilitating peer-to-peer networking in practically oriented HEIs. The results section discusses the empirical results, supported by direct quotes from interviewees and structured codifications and proposition of model dynamics. The final section of the article describes key conclusions and limitations of the model. This study provides valuable insights for university authorities, educators, and policymakers on how digital transformation influences digital pedagogies, quality management, and finally the transition of HEIs.
An Evolutionary Prediction Model for Enterprise Basic Research Based on Knowledge Graph
Authors: Haican Diao , Yanqun Zhang 
Published: June 2024

Abstract

Currently, China's enterprise basic research faces problems due to a need for more systematic guidance and dispersed themes. The construction of an enterprise basic research knowledge map is of great practical significance for tracking cutting-edge technologies, tapping the primitive scientific and technological innovation ability of enterprises, and playing the leading role in enterprise innovation. By mining the intrinsic correlation between the data, a multilayer CNN-LSTM-based correlation prediction model for enterprise basic research is proposed, using the number of published papers of enterprises as the experimental dataset, reasoning and completing the knowledge graph of enterprise basic research, and predicting the future direction of enterprise basic research; and constructing a probability calculation model of enterprise basic research with a multi-attention mechanism, and probabilistically calculating the future hotspot direction of enterprise basic research. The experimental results show that compared with the existing classical model, the recall and F1 value of the multilayer CNN-LSTM evolutionary prediction model are significantly improved. It can more accurately capture the cutting-edge research topics in several types of basic research fields, which provides a new perspective for the related personnel to predict the trend of basic research fields.
Evaluating the Relationship between Periodontal Bone Loss in Maxillary Posterior Teeth and Schneiderian Membrane Thickness
Authors: Ekşi Cemre , Şeker Başak 
Published: June 2024

Abstract

Background
To understand the potential impact of periodontal disease on maxillary sinus health, this study aimed to evaluate the relationship between periodontal bone loss and maxillary sinus membrane thickness using cone beam computed tomography (CBCT).
Methods
Nine hundred thirty-nine maxillary posterior segment images from 527 subjects were retrospectively scanned via CBCT. A total of 826 premolar, 701 first molar and 817 second molar teeth were examined. The maxillary sinuses in each segment were divided into anterior, median and posterior regions according to the tooth roots they were associated with and their membrane thicknesses were measured and categorized. The effects of age and sex on membrane thickness were evaluated. T tests and one-way ANOVA were used to analyze differences between groups, followed by post hoc Tukey tests for multiple comparisons. Additionally, correlation analyses were performed to investigate the relationships between the categorized membrane thicknesses and periodontal bone loss.
Results
A significant positive correlation was found between maxillary sinus membrane thickness and periodontal bone loss in all three regions (p < 0.05). Periodontal bone loss was greater in regions with class IV membrane thickness (p < 0.001). Sinus membrane thickness and periodontal bone loss were greater in men (p < 0.001) and older people (p < 0.05).
Conclusions
This study found a relationship between maxillary sinus membrane thickness and bone loss due to periodontal disease in the maxillary posterior region. Considering the relationship between periodontal disease and sinus infections, it can be concluded that progressive and untreated periodontal disease may be associated with infections in close anatomical structures such as the maxillary sinus. These results may contribute to the development of clinical decisions and treatment plans in implantology practices.
Facile Fabrication of Polymer/Palygorskite Microcapsules via Pickering Emulsion Photopolymerization
Authors: Li Jin , Wang Xinyang , Zhang Pengying , Chen Quan , Min Dandan , Jiang Xiaowu , Gao Xiaoyan , Ni Lingli 
Published: June 2024

Abstract

A facile photocatalytic Pickering emulsion polymerization process was developed to fabricate polymer/clay composite microcapsules. Photolatent Pickering emulsions of oil (monomer, crosslinker, Irgacure 819 and octane) in water were prepared using palygorskite fibers (PAL) as particulate emulsifier. The effect of PAL concentration on the emulsion stabilities was well studied. 3 wt% of PAL fibers were required in order to obtain a stable Pickering emulsion. Moreover, serials of factors on the formation of microcapsules have been investigated, such as PAL concentration, photoinitiator percentage, light intensity, crosslinker/monomer radio and monomer type. Under the appropriate conditions, polymer/PAL microcapsules with spherical morphology can be produced easily. Consequently, a formation mechanism of the microcapsules has been proposed.
Two-step Ulm-Chebyshev-like method for inverse singular value problems with multiple singular values
Authors: Ma Wei , Zhu Yuqing , Dang Yawei 
Published: June 2024

Abstract

In this article, when the given singular values are positive and multiple, we study the convergence of two-step Ulm-Chebyshev-like method for solving the inverse singular value problems is obtained, which extends the result of Ma (2022) [1]. We show that the new method is cubically convergent. Moreover, numerical experiments are given in the last section, which show that the proposed method is practical and efficient.
AMS subject classification. 65F18, 65F15, 15A18
The rate of dunes erosion on the Southern Baltic Sea coast under the influence of the Marie and Nadine double storm in January 2022
Authors: Labuz Tomasz Arkadiusz 
Published: June 2024

Abstract

The paper discusses the conditions for development and the course of the double storm surge caused by the Marie and Nadine cyclones in January 2022. Smaller surges that preceded the main large one have also been presented. The volume of coastal dune erosion caused by storm surges, including the sea level height and wave run-up were analysed, as was the influence of the ratio of beach height to run-up and the volume of dune erosion. The results were obtained based on field measurements of the changes in the morphology of the coast and the waterfront on various sections of the Polish coastline. The dune retreat after selected surges was calculated. The largest dune erosion occurred after the Marie and Nadine storms. The maximum sea level was 1.28 m AMSL. At that height, the water run-up on the coast reached 3-3.2 m AMSL. Mean erosion, defined as the retreat of the dune base, was 4.3 m. However, it was higher in sections where the beach was lower than the water run-up during surges and ranged from 4 to 8 m. Dune erosion reaching up to 8 m occurred on so-called cape sections, where the direction of the coastline changes. The factors that influenced the volume of dune erosion were the different levels of the sea and run-up, as well as the coast’s exposure to waves and the beach height.
High blood pressure in the Emergency Department as an opportunistic screening tool for detection of hypertension
Authors: Bentzel Sara , Manhem Karin , Öhman Ottilia , Abdulla Karzan , Mourtzinis Georgios 
Published: June 2024

Abstract

Hypertension is the most preventable cause of morbidity and mortality, but many individuals are not diagnosed and lack treatment control. High blood pressure (BP) in the emergency department (ED) is commonly observed, but mostly used for short-term evaluation. We aimed to study the usefulness of high BP in the ED as a screening tool for undiagnosed hypertension.
We used the electronic medical record system to identify all patients that had attended the ED at a university hospital from 2018-01-01 to 2018-03-31 and from 2018-07-01 to 2018-09-30 with an obtained BP ≥160/100 mmHg measured at the ED. We excluded patients with previously diagnosed hypertension and patients on any BP-lowering medication. All patients identified where contacted two years after attending the ED, with a letter of consent and a questionnaire regarding diagnosis of hypertension and current medication.
5424 patients attended the ED during the 6-months-period. A total of 271 patients met the inclusion criteria and were asked to participate. 167 individuals (62%) agreed to participate and responded to the questionnaire. Mean age of participants were 63.1 years and 51% were women. 134 patients (80%) had measured their BP after the ED-visit, and 48 (36%) of those had been diagnosed with hypertension. 96% of patients diagnosed with hypertension were on BP-lowering medication.
To follow-up BP ≥160/100 mmHg after an ED visit can reveal undiagnosed hypertension in one third of the patients. Given the amount of undiagnosed hypertension, an ED-measured BP might provide an important tool to detect and start treatment of hypertension.
How Learners’ Trust Changes in Generative AI Over a Semester of Undergraduate Courses
Authors: Song Donggil 
Published: June 2024

Abstract

Artificial intelligence (AI) applications, including advanced machine learning (ML), have received attention in education, and generative AI-powered chatbots like ChatGPT and Copilot have been adopted in diverse educational settings worldwide. However, the actual use of and perception regarding AI-powered chatbots by learners have been under-investigated. Obtaining a more accurate understanding of learners’ perceptions, particularly their trust in AI-powered technology, is crucial for preparing for future education because learners’ trust in the technology itself is significantly related to successful technology adoption in various educational contexts. To address this issue, we focused on undergraduate students’ trust in AI-powered chatbots within their courses and investigated the relationship between their trust levels and learning performance. Additionally, we explored the potential association between learners’ trust levels, self-regulated learning, and computational thinking skills. This research employed an exploratory study design with a regular course setting, and there were no experimental treatments involved. In the results, we found that learners’ trust levels were not correlated with their computational thinking, self-regulated learning, or learning performance. Furthermore, these constructs (i.e., self-regulated learning, computational thinking, and learning performance) did not significantly predict learners’ trust in AI. However, there was a notable difference between high and low performers concerning changes in trust over time. Trust levels among low performers exhibited a significant change over the semester, whereas those of high performers remained relatively stable. The study suggests that expectations regarding trusting generative AI technology can be influenced by trusting intention through performance.
Health Gains Arising from Reduced Risk Consumption:South Africa’s PRIME Example
Authors: Koch Steven F. 
Published: June 2024

Abstract

Objectives: Non-communicable diseases (NCDs) account for over 30% of disability-adjusted life years in South Africa. In this research, we offer an estimate of the potential reduction in NCD incidence that would arise from an improvement in diet, combined with a reduction in both tobacco and alcohol consumption.
Methods: We apply the PRIME model, which simulates the effect of risk reduction on NCD incidence. The model inputs baseline data related to the population, risky consumption behaviour and NCD incidence. The model allows for counterfactual scenarios altering the risky consumption behaviour to yield revised NCD incidence.
Results: We find that reducing salt, tobacco and alcohol, along with improved fruit, vegetable and fiber consumption would yield a 10% reduction in NCDs from the 2018 baseline. NCD incidence reductions arise primarily from ischemic heart disease (49%), cerebrovascular diseases (33%) and bronchus and lung disease (11%).
Conclusion: South Africa’s NCD incidence is high because of relatively poor behavioural choices, despite plans and policies aimed at changing this. South Africa should increase their efforts to reach NCD goals. If the government is able to reduce harmful behaviour, with respect to a number of the underlying consumption choices, NCD incidence is expected to fall precipitously.
Targeting TLR4/NF-κB and Nrf2/HO-1 Crosstalk via Trimetazidine alleviates LPS-induced Depressive Like Behaviors in mice
Authors: Mohamed Sarah S. , Rasheed Nora O. Abdel , Ibrahim Weam W. , Shiha Nesma A. 
Published: June 2024

Abstract

Depression is a global psychiatric disorder that imposes a substantial economic burden. Trimetazidine (TMZ); a well-known anti-ischemic drug, could exert neuroprotection in cerebral ischemia.
Aims: This study aimed to investigate the effect of TMZ in lipopolysaccharide (LPS) mouse model of depression with empathises on its ability to regulate toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) as well as nuclear factor erythroid 2 related factor 2 (Nrf2)/ heme oxygenase-1(HO-1) signaling pathways.
Main methods: Male Swiss albino mice were injected with LPS (500 µg/kg, i.p) every other day alone or concurrently with oral doses of either TMZ (20 mg/kg/day) or escitalopram (Esc) (10 mg/kg/day) for 14 days.
Key findings: Administration of TMZ attenuated LPS-induced animals' despair with decreased immobility time in forced swimming test. Additionally, TMZ diminished LPS–induced neuro-inflammation via inhibition of TLR4/NF-κB pathway contrary to Nrf2/HO-1 cascade activation with consequent increase in reduced glutathione (GSH) and HO-1 levels whereas the pro-inflammatory cytokines; tumor necrosis factor –α (TNF-α) and interleukin (IL)-1β were markedly reduced. Besides, TMZ replenished brain serotonin levels owing to serotonin transporter (SERT) inhibition. Thus, TMZ hindered LPS-induced neuro-inflammation, oxidative stress, serotonin deficiency in addition to its anti-apoptotic effect which was reflected by decreased caspase-3 level. The formerly mentioned neuroprotective effects of TMZ were verified by the histological photomicrographs which revealed prominent neuronal survival with minimal records of neuronal damage.
Significance: Consequently, TMZ is proposed as an affluent nominee for depression management via targeting TLR4/NF-κB and Nrf2/HO-1 pathways.
WWP1 targeting PTEN for polyubiquitination to promote bone metastasis of luminal breast cancer
Authors: Jiang Hao , Li Zhenxi , Xu Wei , Xiao Jianru 
Published: June 2024

Abstract

Luminal breast cancer exhibits a high incidence of bone recurrence when metastasizing to distant organs. The mechanisms underlying the organotropism of luminal breast cancer cells remain unclear. In this study, we aimed to determine the role of WWP1 (WW domain-containing E3 ubiquitin protein ligase 1)-PTEN (Phosphatase and tensin homolog deleted on chromosome ten) interaction in bone tropism in luminal breast cancer. We observed that WWP1 was overexpressed in luminal breast cancer tissues and associated with poor prognosis in breast cancer patients. In luminal breast cancer cells, WWP1 was found to mediate PTEN ubiquitination, resulting in the functional loss of PTEN. As a result, we demonstrate that the WWP1 contributes to bone tropism in luminal breast cancer cells via the polyubiquitination of PTEN. Consequently, WWP1-mediated PTEN polyubiquitination contributed to the early metastasis of luminal breast cancer cells to the bone. Thus, our study provides a mechanistic insight into the bone tropism of luminal breast cancer cells and proposes a potential therapeutic strategy for mitigating cancer metastasis to the bone.
Spatial Data Modelling of Atmospheric Water Availability and Stress in Jharkhand, India
Authors: Roy Priyanka , Gupta Saurabh Kumar , Singh Suraj Kumar , Kanga Shruti 
Published: June 2024

Abstract

The levels of Atmospheric Water Stress (AWS) and Atmospheric Water Availability (AWA) in Jharkhand, India was investigated in this study. The analysis makes use of MODIS NDVI and Terra Climate data that have undergone Google Earth Engine (GEE) processing. Following the computation of mean annual values for Normalized Difference Water Index (NDWI), run-off, precipitation, and Evapotranspiration (ET), AWS and AWA are classified based on these indices. Significant geographical variations in ET, precipitation, runoff, AWS, and AWA are revealed by the results across a few Jharkhand regions. Purbi Singhbhum exhibits significantly higher rates of ET than Garhwa, Palamu, and Chatra, which experience comparatively lower rates. Geographic areas with high levels of AWS, including Sahibganj, Godda, Pakur, Garhwa, and Kodarma, serve as indicators of more severe water scarcity. Consequently, these regions necessitate the implementation of targeted water management strategies. Conversely, varying degrees of AWS are observed in districts including Giridih, Chatra, Jamtara, Latehar, Simdega, and Hazaribagh, underscoring the need for individualized interventions. By identifying regions with limited water availability, the AWA index facilitates the formulation of well-informed resource management decisions. AWS is exacerbated by climate variability, which impacts the distribution of temperatures and precipitation, particularly in regions where AWS levels are high. Local infrastructure development and the implementation of water management strategies are crucial for mitigating the effects of water scarcity.