bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interdigitation of the distal anastomosis between tubed fasciocutaneous flap and cervical esophagus for stricture prevention
Authors: Fujiwara Takashi , Shih Hsiang‐Shun , Chen Chien‐Chang , Tay Sherilyn Keng Lin , Jeng Seng‐Feng , Kuo Yur‐Ren 
Published: January 2011

AbstractObjectives/Hypothesis:Distal end circular stricture is a major complication following circumferential pharyngoesophageal reconstruction with tubed fasciocutaneous free flaps. To reduce the stricture rates, we have incorporated spatulation with interdigitation at the distal anastomosis site. This study investigated whether this procedure could decrease the stricture rate.Study Design:Retrospective review.Methods:There were 51 patients who underwent tubed fasciocutaneous free flap reconstruction following total laryngo‐pharyngo‐esophagectomy between July 2002 and August 2008. The interdigitation technique was applied in 10 patients; the 41 remaining patients underwent simple circumferential anastomosis. This modification technique consists of incising both distal skin tube and cervical esophagus into three triangular parts, respectively, and interdigitation by interposition of these flaps. Of the 10 patients with this procedure, five patients were reconstructed with an anterolateral thigh flap and five with a radial forearm flap. All 10 patients received postoperative radiotherapy. The mean follow‐up period was 30.2 months.Results:Of the 41 patients without any modification, 12 patients (29.3%) developed a stricture; however, in our series of 10 patients undergoing this modification, there was no stricture formation except one (10.0%) who had been reconstructed with a radial forearm flap. The nine remaining patients all achieved a modified or unrestricted full oral diet without complications. Esophagography revealed a wide and patent anastomosis without stricture.Conclusions:This interdigitation technique could prevent circular contracture at the neopharyngoesophageal segment in reconstruction with tubed fasciocutaneous free flaps.
Addition of a minimally invasive medial orbital approach in the endoscopic management of advanced sino‐orbital disease: Cadaver study with clinical correlations
Authors: Ramakrishnan Vijay R. , Suh Jeffrey D. , Chiu Alexander G. , Palmer James N. 
Published: January 2011

AbstractObjectives:Access to the medial orbit traditionally has been gained transcutaneously, with potential for associated soft tissue and lacrimal disruption. Endoscopic transnasal approaches to the medial orbit may be limited in certain scenarios by tumor presence or patient‐specific factors. The medial transconjunctival approach, or transcaruncular approach, has been recently described for access to the medial orbit in orbital decompression and repair of medial blowout fractures. The aim of this study is to determine the utility of this minimally invasive external approach in the endoscopic management of advanced sino‐orbital disease.Methods:This is a cadaver study with additional clinical correlations. The transcaruncular approach was combined with a transnasal endoscopic approach in cadaver dissections performed on eight sides. Five cases are described in which the transcaruncular approach was used as an adjunctive technique in advanced endoscopic sinus surgery.Results:In cadaver dissection, the transcaruncular approach is a simple, reliable method to ligate the ethmoid arteries and place bony cuts along the medial orbital wall. In certain anatomic configurations, supraorbital dissection into the frontal sinus or anterior fossa may be achieved. In the cases examined, exposure of the medial orbital subperiosteal plane allowed for ligation of ethmoid arteries, assessment of periorbital invasion of disease, assistance in tumor dissection, and placement of a malleable retractor for protection of orbital contents.Conclusions:The transcaruncular approach to the medial orbit has certain advantages over the traditional open approach. Ligation of the ethmoid arteries, assessment of the lacrimal sac and periorbita for tumor invasion, protection of orbital contents, and en bloc resection of the periorbita and lamina papyrecea are possible through this route.
Unilateral high vagal paralysis: Relationship of the severity of swallowing disturbance and types of injuries
Authors: Fang Tuan‐Jen , Tam Yuan‐Yun , Courey Mark S. , Li Hsueh‐Yu , Chiang Hui‐Cheng 
Published: January 2011

AbstractObjective:To evaluate the prognoses of high vagal lesions and their association with their clinical presentation, and seek to determine the best strategy of management for each patient.Study Design:Retropective case series with chart review.Materials and Methods:Patients following laryngoplasty from 2001 to 2008 at a tertiary referral voice and swallowing center in Taiwan were reviewed. They were divided into two groups according to the etiologies of high vagal trauma. The pre‐ and posttreatment voice and swallowing functions were reviewed; swallowing status was compared between patient groups.Results:Of 186 consecutive patients who underwent laryngoplasty, 8 females and 9 males were diagnosed of unilateral high vagal damage. One group of 11 patients suffered vagal damaging suddenly from skull base trauma, cerebrovascular accidents, and surgical complications; symptoms of vagal paralysis occurred immediately after those events. The second group was comprised of six patients who lost their high vagal functions gradually from a skull base tumor or mass compression. Feeding tube status was significantly different between the groups. All except one patient in group 2 recovered their voice and swallowing abilities after appropriate laryngoplasty.Conclusions:High vagal nerve damage from skull base surgery or trauma leads to a higher incidence of feeding tube dependency than that from skull base tumor compression. Patients can be treated successfully with an appropriate injection or medialization thyroplasty. Immediate laryngoplasty is suggested for cases right after skull base surgery or trauma.
The use of adalimumab for cricoarytenoid arthritis in ankylosing spondylitis—an effective therapy
Authors: Desuter Gauthier , Duprez Thierry , Huart Caroline , Gardiner Quentin , Verbruggen Gust 
Published: January 2011

AbstractThis report describes cartilaginous regeneration in a cricoarytenoid joint affected by spondyloarthropathy using tumor necrosis factor‐alpha (TNF‐α) blockade, monitored by magnetic resonance (MR) and computed tomography (CT) imaging. This case is interesting for several reasons. It is only the eighth case of destructive ankylosing spondylitis‐related cricoarytenoid arthritis published in the English language literature. It describes, for the first time, full recovery of vocal cord mobility following TNF‐α blockade. It is also the first case to be published with MR imaging demonstrating regeneration of the cricoarytenoid cartilage following treatment. This case represents a landmark in the treatment of patients presenting with destructive arthritis involving the cricoarytenoid joint.
The prevalence of occult metastases in nonsentinel lymph nodes after step‐serial sectioning and immunohistochemistry in cN0 oral squamous cell carcinoma
Authors: Christensen Anders , Bilde Anders , Therkildsen Marianne H. , Mortensen Jann , Charabi Birgitte , Kirkegaard Joergen , Specht Lena , Buchwald Christian von 
Published: January 2011

AbstractObjectives:To examine the prevalence of isolated tumor cells (ITC) and micrometastases (MM) in nonsentinel lymph nodes (NSN) using additional step‐serial sectioning and immunohistochemistry (IHC) as for sentinel lymph nodes (SN).Study Design:Prospective, consecutive, and clinically controlled trial.Methods:Fifty‐one patients with oral cavity squamous cell carcinoma (OSCC) T1–T2 and clinically N0 neck underwent surgical treatment including sentinel‐node biopsy (SNB) assisted selective neck dissection (SND). The location of the SN was determined using dynamic and planar lymphoscintigraphy and SPECT‐CT. The harvested NSN from the neck dissections underwent the same histopathologic examinations as the SN using step‐serial sectioning (SSS) at 150‐micron intervals. Two sections from each level were stained with hematoxylin‐eosin (H&E) and cytokeratin antibodies (AE1/AE3) and examined for tumor deposits. Results were compared with the previous routine examination of the NSN.Results:A total of 403 NSN were examined with a median of 8 per patient. A total of 1/51 patients (2%) had involvement of an additional NSN not found on routine examination. This was the only lymph node with involvement not detected previously. However, this patient had metastases in SN and in another NSN detected on routine examination. The overall incidence of occult metastasis (SN + NSN) was 21.6% (11/51) as previously reported.Conclusions:The incidence of occult metastases in NSN after additional SSS and IHC was 2%. The risk of NSN involvement would seem to be extremely low in patients with early OSCC and negative SN. This study further validates SNB as an accurate staging tool for cN0 early OSCC.
Balloon dilatation of tracheostomal stenosis with cuffed tracheostomy tube. A novel approach to tracheostomal dilatation
Authors: MacKeith Samuel A. C. , Pankhania Miran , Hettige Roland , Gurr Paul 
Published: January 2011

AbstractPostlaryngectomy tracheostomal stenosis is a common complication. Stomal narrowing can be severe, requiring urgent management with dilatation of the stoma. There are numerous ways to achieve this, ranging from forcibly inserting a larger tracheostomy tube, using a graduated dilator, to surgical intervention in the form of a stomaplasty. We describe an alternative technique using a readily available cuffed tracheostomy tube. Laryngoscope, 2011
When to manage level V in head and neck carcinoma?
Authors: Naiboğlu Bariş , Karapinar Uğur , Agrawal Amit , Schuller David E. , Ozer Enver 
Published: January 2011

AbstractObjectives/Hypothesis:As superselective neck dissection strategy is gaining popularity to minimize postoperative morbidity and better life quality, we investigated the metastatic nodal status of level V neck lymph node group for head and neck squamous cell carcinoma in various primary sites. We have also aimed to display the impact of involvement of other nodal groups on level V.Study Design:Retrospective review of histopathologic examination of case series at a comprehensive cancer center.Methods:The study group was composed of 107 patients who underwent a type of neck dissection including level V among 243 patients. The impact of primary site and metastatic nodal status of other levels on metastasis to level V involvement were evaluated.Results:The most common primary tumor site was oropharynx (n = 43), followed by oral cavity (n = 32), larynx (n = 16), carcinoma of unknown primary (n = 10), and hypopharynx (n = 6). General pathologic N positivity for all levels was 78.3% (76 of 97) when 10 carcinoma of unknown primary patients were excluded. Level V was involved in 13 of 107 (12.1%) patients. Level V was not involved in any patient when the other levels were not involved (0 of 21). Even when considering only N+ patients, the ratio of N positivity for level V is still <20% (13 of 86, 15.1%).Conclusions:Because level V was not involved in any patient when the other levels were not involved, it might be reasonable to preserve level V especially in clinically and intraoperatively N0 patients. Laryngoscope, 2011
Th1/Th2 Cytokine profiles in G+/G− bacteremia in pediatric hematology/oncology patients
Authors: Tang Yongmin , Liao Chan , Xu Xiaojun , Song Hua , Shi Shuwen , Yang Shilong 
Published: January 2011

AbstractBackgroundEarly diagnosis of infection and appropriate choice of antibiotics are essential not only to improve the prognosis of the patients but also to prevent from the abuse of the antibiotics in hematology/oncology children at the time of neutropenia after intensive chemotherapy.ProcedureWe evaluated the quantification of Th1/Th2 cytokines with flow cytometry bead assay (CBA) in 145 hospitalized febrile hematology/oncology children with positive blood culture to seek for a rapid diagnostic method to determine the type of infection.ResultsIL‐4, IL‐6, IL‐10, TNF‐α, and IFN‐γ levels from both G− and G+ bacteremia groups were significantly higher than those of controls (P < 0.001). The median levels of IL‐6, IL‐10, TNF‐α of Group G− were 525.4, 96.0, and 6.9 pg/ml, respectively, significantly higher than those of Group G+ (150.0, 22.6, and 4.5 pg/ml, respectively, P < 0.001). According to the different degrees of increased IL‐6 and IL‐10 levels, we named the G− bacterial infection related cytokine profile G− BIRCP and the G+ BIRCP. The specificity and sensitivity of BIRCP prediction for G− and G+ bacteria cultures were 60.2% and 75.4%, 66.8% and 70.1%, respectively. Similar therapeutic efficacy was achieved between BIRCP‐based and broad‐spectrum antibiotics groups (86.1% vs. 89.3%, P > 0.05), which was significantly increased as compared with that (65.5%, P < 0.05) of empirical group.ConclusionsThese results showed the promising use of the IL‐6/IL‐10/TNF‐α determination with CBA technology for the early and rapid diagnosis, evaluation of G+/G− bacteremia in pediatric hematology/oncology patients. Pediatr Blood Cancer 2012; 58: 50–54. © 2011 Wiley Periodicals, Inc.
Resistive switching and changes in microstructure
Authors: Schroeder Herbert , Pandian Ramanathaswamy , Miao Jun 
Published: January 2011

AbstractThe long‐known resistive switching (RS) effect in thin film metal/insulator/metal (MIM) stacks has gained tremendous interest in the last decade because of promising properties and geometries for a resistive memory device (ReRAM) indicating a strong competition for DRAM and FLASH in future ultra‐high integrated circuits. In contrast to numerous contributions for the electric behaviour and many, often very detailed assumptions for the mechanisms, much less is known about the microstructure and its relation to the observed resistance changes, forming and switching. This paper reports experiments combining electric measurements with microstructure characterization in electron microscopes for both, in situ and also ex situ (i.e. sequential). The results, mainly on Pt/TiO2/Pt stacks, indicate mostly heavy damage of the thin film microstructure associated with the forming, although these damaged samples still show stable unipolar and bipolar resistive switching. These findings are discussed and compared to the scarce microstructure information in the literature which is presented in a short review at the end. From all the information it has to be concluded that much more about the microstructure changes related to resistive switching is urgently needed in order to model the RS based on data instead of assumptions.
Local vibrational modes of the oxygen trimer in Si
Authors: Murin L. I. , Tolkacheva E. A. , Markevich V. P. , Peaker A. R. , Svensson B. G. , Lindström J. L. 
Published: January 2011

AbstractIn the present work we have exploited different kinds of defect engineering (hydrogenation, irradiations at elevated temperatures etc) to enhance the formation of small oxygen clusters in Si crystals grown by the Czochralski technique. In these ways we manage to increase significantly the concentration of a defect giving rise to a local vibrational mode (LVM) band at 1006 cm‐1. The highest concentration of the defect is achieved in samples first enriched with the vacancy‐trioxygen complex (VO3) and then electron irradiated. It is found that an interaction of the radiation‐induced Si self‐interstitials with VO3 occurs, so resulting in the appearance of a complex incorporating three interstitial oxygen atoms. The results obtained give strong support for the assignment of the 1006 cm‐1 band to the oxygen trimer. Three LVM bands positioned at 537, 723 and 1020 cm‐1 are found to develop in a similar way to the 1006 cm‐1 band and all of them are suggested to arise from the trimer. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Characterization of InGaAsSbN layers grown on InP by MBE
Authors: Yoshikawa M. , Miura K. , Iguchi Y. , Kawamura Y. 
Published: January 2011

AbstractOptical and electrical properties of the InGaAsSbN layers grown by molecular beam epitaxy (MBE) on InP substrates were studied in comparison with InGaAsN layers. It was found that the optical properties of the InGaAsSbN layer characterized by photoreflectance (PR) and photoluminescence (PL) measurements are superior to those of InGaAsN layer. In addition, electrical properties characterized by Hall measurements were also improved by adding Sb atoms. Annealing studies on photoluminescence properties of the InGaAsSbN layer revealed that the PL intensity increases and the PL spectral half width decreases upon annealing up to 700 °C. These results indicate that post‐annealing is still necessary for InGaAsSbN layers to improve crystalline quality (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Photo‐polymerization of hole‐doped C60 grown by liquid‐liquid interfacial precipitation method
Authors: Koide Daiki , Iwata Nobuyuki , Yamamoto Hiroshi 
Published: January 2011

AbstractThe aim of our study is to synthesize an amorphous 3D C60 polymer at the bulk scale for various application fields. To polymerize the C60 molecules, powders of C60 and I2 were mixed for hole doping and the free electron laser (FEL) photopolymerization was carried out in vacuum. FEL with the wavelength of 500 nm was irradiated. In order to promote the polymerization degree, I2 was doped in alcohol while the liquid‐liquid interfacial precipitaiton (LLIP) growth of C60. It is concerned that the mixture process in air was probably accompanied with a reaction with oxygen, and reduced the polimerization degree. Specimens were analyzed by micro‐Raman spectra. To analyze a polymerization degree, one of the Raman‐active Ag modes, called pentagonal pinch mode Ag (2), is regularly investigated. From the results of Raman spectra, the important parameters to obtaine and promote polymerization phase was rather high pressure more than at least 600 MPa, I2 doping, and the FEL irradiation. So‐called F phase was obtained probably due to the reduction of energy barrier for transformation from sp2 to sp3 and high energy power density of micropulses of the FEL (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Titanium tetrachloride as electrophilic activator in the technology of inorganic polysulfides
Authors: Ysupova A. A. , Shamov A. G. , Ahmetova R. T. , Pervushin V. A. , Hatsrinov A. I. 
Published: January 2011

AbstractThe technology of the inorganic sulphides and composition materials on their base from the different silica‐containing products is described. The mechanism of the sulphides formation is analyzed in detail under the different ways of sulphurous components. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
A first‐principles study of diatomic NiAl: Ground state, structure, and spectroscopic constants
Authors: Cundari Thomas R. , Janardan Smitha S. , Olatunji‐Ojo Olayinka , Wilson Brent R. 
Published: January 2011

AbstractA computational study of diatomic NiAl is reported. Molecular properties evaluated include the equilibrium bond length (re), equilibrium stretching frequency (ωe), doublet‐quartet energy splitting, and nickel‐aluminum bond strength. Several interesting conclusions have resulted from this research. First, convergence in calculated properties is smoother with recently reported correlation consistent basis sets than earlier basis sets for Ni and Al. Second, with the exception of bond strength, basis set limit properties extrapolated using correlation basis sets are in agreement with reported data. Third, this research suggests that caution may be needed with regard to the use of DFT for developing interatomic potentials for larger scale simulations. For example, B97‐1 showed better agreement with reported re for 2NiAl than B3LYP. However, the situation was reversed for the calculation of ωe. With respect to bond strength, the situation is unclear due to the scatter among experiment and calculations. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
Quantum bifurcation in a coulombic‐like potential
Authors: Yang Ciann‐Dong , Weng Hung‐Jen 
Published: January 2011

AbstractBecause of the lack of nonlinear dynamics, up to now no bifurcation phenomenon in its original sense has been discovered directly in quantum mechanical systems. Based on the formalism of complex‐valued quantum mechanics, this article derives the nonlinear Hamilton equations from the Schrödinger equation to provide the necessary mathematic framework for the analysis of quantum bifurcation. This new approach makes it possible to identify quantum bifurcation by the direct evidence of the sudden change of fixed points and their surrounding trajectories. As a practical application of the proposed approach, we consider the quantum motion in a Coulombic‐like potential modeled by V(r) = A/r2 − B/r, where the first term describes the centrifugal trend and the second deals with the Coulombic attraction. As the bifurcation parameter evolves, we demonstrate how local and global bifurcations in quantum dynamics can be identified by inspecting the changes of fixed points and their surrounding trajectories. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
Doing good deeds in times of need: a strategic perspective on corporate disaster donations
Authors: Muller Alan , Kräussl Roman 
Published: January 2011

AbstractMajor corporations often respond charitably in times of disaster. However, disasters can also impose nontrivial costs on firms themselves, and under adverse conditions, firms typically donate less, not more. This paper takes a strategic perspective on corporate magnanimity in times of crisis by looking at the relationship between firm value, reputation, and donations by U.S. Fortune 500 firms in the case of Hurricane Katrina. In general, we find that Katrina's landfall was associated with significant negative abnormal stock returns. In particular, we find that a reputation for social irresponsibility was associated with both the greatest drop in stock prices and the greatest likelihood of making a subsequent charitable donation in response to the disaster. Copyright © 2011 John Wiley & Sons, Ltd.
MNC strategies, exogenous shocks, and performance outcomes
Authors: Li Sali , Tallman Stephen 
Published: January 2011

AbstractThis paper examines the effect of international diversification on multinational corporation (MNC) performance in the face of exogenous shocks in the global business environment, and the extent to which MNCs' internationalization aids or impedes post‐shock performance. We use the September 11, 2001 attacks as a research setting to investigate the relationship between international diversification and MNC performance after a sudden change in the environment. The empirical tests on a sample of 191 U.S. MNCs and a matched sample of non‐U.S. MNCs indicate that the level of pre‐September 11 international diversification is negatively correlated with immediate cumulative abnormal returns to shares, but positively correlated with longer‐term performance. Copyright © 2011 John Wiley & Sons, Ltd.
Physicochemical properties and in vitro digestibility of resistant starch from mung bean (Phaseolus radiatus) starch
Authors: Li Suling , Gao Qunyu , Ward Rachelle 
Published: January 2011

AbstractRS from mung bean starch was prepared by autoclaving, pullulanase debranching, and retrogradation. Physicochemical properties, crystalline structure, and in vitro digestibility of selected RS samples with different RS content were investigated. Compared to native starch, AAM content of RS increased but MW decreased greatly. SEM clearly showed RS samples exhibited irregular shaped fragments with compact structure. XRD pattern indicated that RS samples had typical B‐type pattern with sharp peaks at 17.0°, 22.2°, and 23.9° 2θ. The relative crystallinity, gelatinization temperatures, and enthalpy increased with increasing RS content. The α‐amylase digestibility of RS was lower than that of native starch. The results suggested that the decrease in enzymatic digestion of RS might due to compact and ordered crystalline structures after debranching and recrystallization.