bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal‐crosslinked polyacrylonitrile fiber compacts
Authors: Kalfon‐Cohen E. , Harel H. , Saadon‐Yechezkia M. , Timna K. , Zhidkov T. , Weinberg A. , Marom G. 
Published: August 2009

AbstractPolyacrylonitrile (PAN) textile fibers, in the form of fabrics or threads, were compacted in a heat‐pressure cycle and crosslinked by nitrile polymerization to form a thermoset composite article, whose mechanical properties were found to surpass those of commercially available polypropylene (PP) fiber counterparts. Additional advantages of the PAN compacts included their significant thermal stability (>300°C, i.e., twice that of PP) in addition to their flame retardancy, thereby rendering them as the structural material of choice for applications where heat protection and fire resistance are essential. Copyright © 2009 John Wiley & Sons, Ltd.
A rapid isolation and identification method for blocked N‐terminal peptides by isothiocyanate‐coupled magnetic nanoparticles and MS
Authors: Zhao Liyan , Zhang Yangjun , Wei Junying , Cao Dong , Liu Kehui , Qian Xiaohong 
Published: August 2009

AbstractA quick isolation and identification of N‐blocked peptides from protein digest mixtures were achieved by diisothiocyanate or isothiocyanate‐coupled magnetic nanoparticles and MS. After protein digests were guanidinated and then mixed with diisothiocyanate or isothiocyanate‐coupled magnetic nanoparticles, unmodified N‐terminal peptides were covalently bound to magnetic nanoparticles, and can be removed from the mixture under magnetic field. Therefore, N‐blocked peptides could be isolated and analyzed by MALDI or ESI MS. This new strategy was demonstrated with model peptides, proteins, and the lysates of HepG2 cells.
Proteomic analysis from haploid and diploid embryos of Quercus suber L. identifies qualitative and quantitative differential expression patterns
Authors: Gómez Aranzazu , López Juan Antonio , Pintos Beatriz , Camafeita Emilio , Bueno Ma Ángeles 
Published: August 2009

AbstractQuercus suber L. is a Mediterranean forest species with ecological, social and economic value. Clonal propagation of Q. suber elite trees has been successfully obtained from in vitro‐derived somatic and gametic embryos. These clonal lines play a main role in breeding and genetic studies of Q. suber. To aid in unravelling diverse genetic and biological unknowns, a proteomic approach is proposed. The proteomic analysis of Q. suber somatic and gametic in vitro culture‐derived embryos, based on DIGE and MALDI‐MS, has produced for the first time proteomic data on this species. Seventeen differentially expressed proteins have been identified which display significantly altered levels between gametic and somatic embryos. These proteins are involved in a variety of cellular processes, most of which had been neither previously associated with embryo development nor identified in the genus Quercus. Some of these proteins are involved in stress and pollen development and others play a role in the metabolism of tannins and phenylpropanoids, which represent two of the major pathways for the synthesis of cork chemical components. Furthermore, the augmented expression levels found for specific proteins are probably related to the homozygous state of a doubled‐haploid sample. Proteins involved in synthesis of cork components can be detected at such early stages of development, showing the potential of the method to be useful in searching for biomarkers related to cork quality.
A guide to the Proteomics Identifications Database proteomics data repository
Authors: Vizcaíno Juan Antonio , Côté Richard , Reisinger Florian , M. Foster Joseph , Mueller Michael , Rameseder Jonathan , Hermjakob Henning , Martens Lennart 
Published: August 2009

AbstractThe Proteomics Identifications Database (PRIDE, www.ebi.ac.uk/pride) is one of the main repositories of MS derived proteomics data. Here, we point out the main functionalities of PRIDE both as a submission repository and as a source for proteomics data. We describe the main features for data retrieval and visualization available through the PRIDE web and BioMart interfaces. We also highlight the mechanism by which tailored queries in the BioMart can join PRIDE to other resources such as Reactome, Ensembl or UniProt to execute extremely powerful across‐domain queries. We then present the latest improvements in the PRIDE submission process, using the new easy‐to‐use, platform‐independent graphical user interface submission tool PRIDE Converter. Finally, we speak about future plans and the role of PRIDE in the ProteomExchange consortium.
Bronchoalveolar lavage fluid proteomic patterns of sulfur mustard‐exposed patients
Authors: Mehrani Hossein , Ghanei Mostafa , Aslani Jafar , Golmanesh Leila 
Published: August 2009

AbstractSulfur mustard is an alkylating agent that reacts with ocular, respiratory, cutaneous, and bone marrow tissues. Main late respiratory complications are chronic obstructive pulmonary disease, bronchiectasis, asthma, and bronchiolitis obliterans. The aim of the present study was to identify differentially expressed proteins in bronchoalveolar lavage (BAL) fluid of control healthy and sulfur mustard‐exposed lung disease patients. The BAL protein profile of ten healthy and 30 exposed patients with mild, moderate, and severe conditions (ten males in each group) were separated with 2‐D SDS‐PAGE and differentially expressed protein spots were successfully identified with MALDI TOF TOF MS. Among the differentially expressed proteins we observed a significant increase in vitamin D binding protein isoforms, haptoglobin isoforms, and fibrinogen especially in exposed moderate and severe lung diseases patients (p<0.01). Moreover, compared with healthy controls, significant decreases was noted in calcyphosine, surfactant protein A, and transthyretin in these patients (p<0.01). Apolipoprotein A1 was detected in all patients' BAL fluid but none of the healthy controls. Furthermore, S100 calcium‐binding protein A8 was only detected in BAL fluid of moderate and severe groups. These findings will be useful to improve current methods of monitoring and helps to identify new therapeutic targets for treatment of this complicated illness.
The solution structure and dynamics of the DH‐PH module of PDZRhoGEF in isolation and in complex with nucleotide‐free RhoA
Authors: Cierpicki Tomasz , Bielnicki Jakub , Zheng Meiying , Gruszczyk Jakub , Kasterka Marta , Petoukhov Maxim , Zhang Aming , Fernandez Erik J. , Svergun Dmitri I. , Derewenda Urszula , Bushweller John H. , Derewenda Zygmunt S. 
Published: August 2009

AbstractThe DH‐PH domain tandems of Dbl‐homology guanine nucleotide exchange factors catalyze the exchange of GTP for GDP in Rho‐family GTPases, and thus initiate a wide variety of cellular signaling cascades. Although several crystal structures of complexes of DH‐PH tandems with cognate, nucleotide free Rho GTPases are known, they provide limited information about the dynamics of the complex and it is not clear how accurately they represent the structures in solution. We used a complementary combination of nuclear magnetic resonance (NMR), small‐angle X‐ray scattering (SAXS), and hydrogen‐deuterium exchange mass spectrometry (DXMS) to study the solution structure and dynamics of the DH‐PH tandem of RhoA‐specific exchange factor PDZRhoGEF, both in isolation and in complex with nucleotide free RhoA. We show that in solution the DH‐PH tandem behaves as a rigid entity and that the mutual disposition of the DH and PH domains remains identical within experimental error to that seen in the crystal structure of the complex, thus validating the latter as an accurate model of the complex in vivo. We also show that the nucleotide‐free RhoA exhibits elevated dynamics when in complex with DH‐PH, a phenomenon not observed in the crystal structure, presumably due to the restraining effects of crystal contacts. The complex is readily and rapidly dissociated in the presence of both GDP and GTP nucleotides, with no evidence of intermediate ternary complexes.
Use of antimicrobial methylcellulose films to control Staphylococcus aureus during storage of Kasar cheese
Authors: Ayana Belgizar , Turhan K. Nazan 
Published: August 2009

AbstractOlive leaf extract (OLE) (Olea europaea L.) is a natural product that has antimicrobial effect on many food pathogens. In this study, methylcellulose (MC) based antimicrobial films containing 0.5–3% (w/v) OLE and glycerol (1.6%, v/v) were produced. The effects of OLE amount on the water vapour permeability (WVP), mechanical and antimicrobial properties of the films were investigated. The films were effective against Staphylococcus aureus (ATCC 25923). The OLE in the film solution caused a decrease in WVP and elongation (E), and an increase in tensile strength (TS). The MC films containing 1.5% (w/v) OLE were applied on Kasar cheese slices inoculated with S. aureus. The count of S. aureus decreased 0.68 and 1.22 log cycle at the 7th and 14th days, respectively. Copyright © 2009 John Wiley & Sons, Ltd.
Victims arrested for domestic violence: unintended consequences of arrest policies
Authors: Hovmand Peter S. , Ford David N. , Flom Ingrid , Kyriakakis Stavroula 
Published: August 2009

AbstractDomestic violence is a major social problem. In the United States, the failure of communities and police departments to intervene resulted in a push to implement pro‐ and mandatory arrest policies for domestic violence. These policies have led to an unexpected increase in the number of victim arrests. Competing explanations have been offered. This paper describes the development of a system dynamics model of victim arrests. Results of model structure analysis suggest that these policies may have created or strengthened a crossover mechanism that shifts the risk of arrests in domestic violence cases from aggressors to victims. Model analysis also demonstrates how the changing role of cooperation between advocates and police can help explain the trends in victim arrests. Implications for research and policy are discussed. Copyright © 2009 John Wiley & Sons, Ltd.
Structural and Magnetic Characterisation of La1+xSr1–xCo0.5M0.5O4±δ (M = Cr, Mn)
Authors: El Shinawi Hany , Greaves Colin 
Published: August 2009

AbstractThe K2NiF4 phases La1+xSr1–xCo0.5Cr0.5O4±δ (x = 0, 0.15) and La1+xSr1–xCo0.5Mn0.5O4±δ (x = 0, 0.2) have been synthesised and examined by X‐ray powder diffraction, thermal analysis, neutron powder diffraction and magnetic susceptibility measurements. Mn3+/Co3+ and Cr3+/Co3+ states predominate in the oxidised forms. Structural stability and crystal symmetry are retained under reducing conditions which cause reduction of Co3+ into Co2+ and the creation of oxide ion vacancies within the equatorial planes of the K2NiF4 structure. Excess oxygen in La1.2Sr0.8Co0.5Mn0.5O4.1 is accommodated in the ideal interstitial positions (0, 0.5, 0.25) of the tetragonal structure of these materials in an oxygen/air atmosphere. No long‐range magnetic order has been observed because of competing AFM and FM interactions in these B‐site disordered materials.
Seltenerdethenidhalogenide Ln2n+6(C2)n+4X2n+2: Darstellung, Struktur, Verwachsung und Verzwilligung
Authors: Mattausch Hansjürgen , Kienle Lorenz , Duppel Viola , Hoch Constantin , Simon Arndt 
Published: August 2009

AbstractPreparation, crystal structure, intergrowth and twinning of the compounds La10(C2)6Br6, Ce10(C2)6Br6 and Gd10(C2)6Cl6 are described. The compounds Ln10(C2)6X6 are formed by heating mixtures of LnX3, Ln und C in tantalum capsules under argon with the ratio LnX3:Ln:C = 2:4:6 for La10(C2)6Br6 at 1040 °C, 30 d (yield ca. 20 %), Ce10(C2)6Br6 at 1200 °C, 12 d, (80 %), Pr10(C2)6Br6 at 1140 °C, 5 d, (20 %) and 2:8:12 for Gd10(C2)6Cl6 at 1170 °C, 39 d, (100 %). They crystallize isotypical in a new structure type in C2/m with a = 22.809(5) Å, b = 3.9855(8) Å, c = 16.599(3) Å, β = 123.32(3)° (La10(C2)6Br6), a = 22.483(5) Å, b = 3.9253(8) Å, c = 16.375(3) Å, β = 123.15(3)° (Ce10(C2)6Br6), a = 22.360(10) Å, b = 3.895(2) Å, c = 16.269(8) Å, β = 123.44(3)° (Pr10(C2)6Br6) and a = 21.507(4) Å, b = 3.7193(7) Å, c = 15.331(3) Å, β = 123.34(3)° (Gd10(C2)6Cl6). The structure of Ln10(C2)6X6 is composed of Ln octahedra centered by (C2) groups, which are connected through common edges to form sheets which are further connected perpendicularly by chains of Ln triple octahedra to form tunnels, which contain the X atoms coordinating the triangular faces of the Ln octahedra. The compounds are semiconductors according to ionic formulations (Ln3+)10(C24–)6(X–)6 suggested by the C=C double bond assignment.
Impact of the Standardized Medial‐to‐Lateral Approach on Outcome of Laparoscopic Colorectal Resection
Authors: Poon Jensen T. C. , Law Wai‐Lun , Fan Joe K. M. , Lo Oswen S. H. 
Published: August 2009

AbstractBackgroundBeginning in 2004, a standardized medial‐to‐lateral approach was adopted in laparoscopic colorectal resection (LapCR) in our institution. The present study aimed to compare the outcomes of patients operated on by this approach with those who were operated on prior to the adoption of this technique.MethodsData were retrieved from a prospectively collected database on LapCR. The control group included 196 patients operated on from January 2002 to December 2003 and the medial approach group included 224 patients who underwent operations from January 2005 to December 2007. The patient characteristics, operative details, pathology, and surgical outcomes of the two groups were compared.ResultsThe patient demographics, types of operation and pathology did not show any statistically significant difference. The medial approach group was associated with significantly less median blood loss [100 (interquartile range [IQR]: 50–174) ml versus 150 (IQR:100–300) ml; p < 0.001], shorter hospital stay [4 (IQR: (4–7) versus 7 (5–9) days; p < 0.001], and more lymph nodes harvested [12 (7–17.5) versus 10 (6–15); p = 0.001]. Significantly earlier bowel function recovery was observed in the medial approach group. The mortality and complications did not show any difference.ConclusionsA standardized medial‐to‐lateral approach for LapCR is associated with less blood loss, earlier return of bowel function, shorter hospital stay, and increased number of lymph nodes harvested. This should be the preferred approach in LapCR.
Constructing a relativistic heat flow by transport time steps
Authors: Puel Marjolaine , McCann Robert J. 
Published: August 2009

An alternative construction to Andreu et al. (2005) [12] is given for

L_{w}^{1}([0,T],\mathrm{BV}(\Omega ))

solutions to the relativistic heat equation (1) (see Brenier (2003) [14], Mihalas and Mihalas (1984) [37], Rosenau (1992) [40], Chertock et al. (2003) [20], Caselles (2007) [19]) under the assumption of initial data bounded from below and from above. For that purpose, we introduce a time discretized scheme in the style of Jordan et al. (1998) [30], Otto (1996) [38] involving an optimal transportation problem with a discontinuous hemispherical cost function. The limiting process is based on a monotonicity argument and on a bound of the Fisher information by an entropy balance characteristic of the minimization problem.

Résumé

Nous présentons ici une construction alternative à celle d'Andreu et al. (2005) [12] de solution

L_{w}^{1}([0,T],\mathrm{BV}(\Omega ))

de l'équation de la chaleur relativiste (1) (voir Brenier (2003) [14], Mihalas et Mihalas (1984) [37], Rosenau (1992) [40], Chertock et al. (2003) [20], Caselles (2007) [19]) dans le cas de conditions initiales bornées inférieurement et supérieurement. Pour cela, nous introduisons un schéma discret en temps dans le style de Jordan et al. (1998) [30], Otto (1996) [38] basé sur un problème de transport optimal faisant intervenir une fonction de coût hémisphérique et discontinue. Le passage à la limite lorsque le pas de temps tend vers zéro repose sur un argument de monotonie et une borne de l'information de Fisher par la variation de l'entropie, inégalité caractéristique du problème de transport optimal.
Controllability on the group of diffeomorphisms
Authors: Agrachev A.A. , Caponigro M. 
Published: August 2009

Given a compact manifold

M

, we prove that any bracket generating family of vector fields on

M

, which is invariant under multiplication by smooth functions, generates the connected component of the identity of the group of diffeomorphisms of

M

.

Résumé

Soit

M

une variété compacte, nous montrons que toute famille de champs de vecteurs satisfaisant la condition du rang et étant invariante par multiplication par fonctions lisses engendre la composante connexe de l'identité du groupe

\mathrm{Diff}M

.
Choquet simplices as spaces of invariant probability measures on post-critical sets
Authors: Cortez María Isabel , Rivera-Letelier Juan 
Published: August 2009

A well-known consequence of the ergodic decomposition theorem is that the space of invariant probability measures of a topological dynamical system, endowed with the weak

∗

topology, is a non-empty metrizable Choquet simplex. We show that every non-empty metrizable Choquet simplex arises as the space of invariant probability measures on the post-critical set of a logistic map. Here, the post-critical set of a logistic map is the

ω

-limit set of its unique critical point. In fact we show the logistic map

f

can be taken in such a way that its post-critical set is a Cantor set where

f

is minimal, and such that each invariant probability measure on this set has zero Lyapunov exponent, and is an equilibrium state for the potential

−\mathrm{\ln }|f^{′}|

.

Résumé

Une conséquence bien connue du théorème de décomposition ergodique est que l'espace des mesures de probabilité invariantes d'un système dynamique topologique est un simplexe de Choquet métrisable et non vide. On montre que tout simplexe de Choquet métrisable et non vide se réalise comme l'espace des mesures de probabilité invariantes sur l'ensemble post-critique d'une application logistique. Ici, l'ensemble post-critique d'une application logistique est l'ensemble

ω

-limite de son unique point critique. En effet, on démontre que l'application logistique

f

peut être choisie de telle façon que son ensemble post-critique soit un ensemble de Cantor où

f

est minimal, et tel que chaque mesure de probabilité invariante sur cet ensemble soit d'exposant de Lyapunov null, et un état d'équilibre pour le potentiel

−\mathrm{\ln }|f^{′}|

.
Wrong Site Surgery Near Misses and Actual Occurrences
Authors: Blanco Mary , Clarke John R. , Martindell Denise 
Published: August 2009

ABSTRACTUnder coordination by the Patient Safety Authority, staff members in facilities across Pennsylvania analyzed 97 wrong site surgery near misses and 44 actual occurrences using a common analysis form from August 2007 to August 2008. These assessments were aggregated and compared by the Patient Safety Authority.Assessments in which near misses were identified that did not advance to actual wrong site occurrences were significantly more likely to report compliance with patient identification and preoperative reconciliation protocols, accurate scheduling, notation of the surgical site on the consent form, participation of the surgeon in preoperative verification, participation of all surgical team members in the time out, time outs performed with the site marking visible after draping, and the surgeon explicitly empowering team members to speak up if concerned and acknowledging concerns when expressed. AORN J 90 (August 2009) 215–222. © AORN, Inc, 2009.
A Synthesis of the Literature on “Competence” as It Applies to Perioperative Nursing
Authors: Gillespie Brigid Mary , Hamlin Lois 
Published: August 2009

ABSTRACTPerioperative competence is an eclectic concept that has been difficult to define and even more difficult to measure. Competence has been described in relation to standards of practice with little emphasis placed on its interpersonal aspects. This article presents a synthesis of the literature focused on perioperative nurse competence.Although specialized knowledge in the form of technical proficiency is important, it is no longer the only indicator of perioperative competence. The findings in this synthesis attest to the increased awareness and emphasis given to human factors—recognition that teamwork, communication, coordination, and leadership also affect human performance. Based on these findings, the next important step would be to develop and test these categories of competence empirically. AORN J 90 (August 2009) 245–258. © AORN, Inc, 2009.
Relationship between methylation status of ERCC1 promoter and radiosensitivity in glioma cell lines
Authors: Liu Zhi‐Gang , Chen Hua‐Yun , Cheng Jing‐Jian , Chen Zhong‐Ping , Li Xiao‐Nan , Xia Yun‐fei 
Published: August 2009

AbstractIonizing radiation represents one of the most important therapies for glioma, a lethal primary brain tumor, while radiotherapy remains a challenge for radiation oncologist because of radioresistance. Radiosensitivity of gliomas determines radiotherapy efficacy. Evidence demonstrated that methylation of CpG Island in the promoter region may result in gene silencing. This study was designed to determine the relationship between methylation status of ERCC1 promoter region and radiosensitivity in glioma cell lines. We investigated the expression levels of ERCC1 transcripts and protein in GBM cell lines. Colony forming experiments was used to measure surviving fraction at 2 Gy (SF2) in four human glioma cell lines, MGR1, MGR2, SF767 and T98G. Methylation status in the promoter region of ERCC1 in these glioma cell lines was determined by using bisulphate sequencing and MSP analysis. Radiosensitivity was examined to be heterogeneous in these glioma cell lines. There was a statistical difference in the radiosensitivity between glioma cell lines with and without methylation of ERCC1 gene promoter CpG islands. Furthermore, we promoted ERCC1 expression by 5‐azacytidine treatment which resulted in the reduction of radiation‐induced cell killing in radiosensitive cell lines. Our data indicate that methylation status of ERCC1 is associated with radiosensitivity in glioma cell lines. It could be used as a new biomarker for predicting the radiosensitivity of human gliomas.
Rhythmic pattern of PCA opioid demand in adults with cancer pain
Authors: Schiessl C. , Schestag I. , Sittl R. , Drake R. , Zernikow B. 
Published: August 2009

ABSTRACTIntroduction: Patient‐controlled analgesia (PCA) has an established role in managing postoperative pain and has been successfully used in‐patients with cancer pain. The variation of opioid requirement over a 24h period for patients with cancer pain is debated with suggestions of reduced need over night.Methods: Retrospective review of 10years (1997–2006) data of all in‐patients with cancer pain treated with strong opioids delivered by PCA.Results: 141 patients with cancer pain had a mean cumulative 10day morphine equivalent dose per patient of 671mg (median 470mg; range 10–2170mg). At night (10:01pm to 06:00am) the patient's self administered less bolus doses (69mg, (25%)) than during the other two 8h periods (06:01am to 02:00pm, 91mg (33%) and 02:01pm to 10:00pm, 116mg (42%)). In 8 out of 10days a significant variation in bolus requests was observed with significantly less bolus requests during the night (Friedman test, p<0.05). Furthermore, the median number of delivered bolus requests per patient, at night, was 2–3 compared to the morning and afternoon periods of 3–7 and 3.5–6, respectively.Conclusion: PCA met individual patient's opioid needs in a safe and effective manner despite a large inter‐individual variability in opioid consumption. Moreover, the study indicated a pattern of less opioid requirement at night.