bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inhibition of neointimal formation by trans‐resveratrol: Role of phosphatidyl inositol 3‐kinase‐dependent Nrf2 activation in heme oxygenase‐1 induction
Authors: Kim Jung Woo , Lim Sung Chul , Lee Moo Yeol , Lee Jeong Woon , Oh Won Keun , Kim Sang Kyum , Kang Keon Wook 
Published: May 2010

AbstractNeointima, defined as abnormal growth of the intimal layer of blood vessels, is believed to be a critical event in the development of vascular occlusive disease. Although resveratrol's inhibitory effects on proliferation and migration of vascular smooth muscle cells has been reported, its activity on neointimal formation is still unclear. Oral administration of trans‐resveratrol significantly suppressed intimal hyperplasia in a wire‐injured femoral artery mouse model. In cultured vascular smooth muscle cells, trans‐resveratrol inhibited platelet‐derived growth factor‐stimulated DNA synthesis and cell proliferation with down‐regulation of cyclin D and pRB. Moreover, platelet‐derived growth factor‐induced production of reactive oxygen species was inhibited by trans‐resveratrol and the compound induced heme oxygenase‐1 (HO‐1). The anti‐proliferative activity of trans‐resveratrol was reversed by an HO‐1 inhibitor, ZnPPIX. Subcellular fractionation and reporter gene analyses revealed that trans‐resveratrol increased the level of nuclear Nrf2 and antioxidant response element reporter activity, and that these were essential for the induction of HO‐1. Trans‐resveratrol also enhanced the activities of phosphatidyl inositol 3‐kinase and extracellular signal regulated kinase, and phosphatidyl inositol 3‐kinase was required for Nrf2/antioxidant response element‐dependent HO‐1 induction. These data have significant implications for the elucidation of the pharmacological mechanism by which trans‐resveratrol prevents vascular occlusive diseases.
Numerical solution of the heat equation with non‐linear, time derivative‐dependent source term
Authors: Pieper M. , Klein P. 
Published: May 2010

AbstractThe mathematical modeling of heat conduction with adsorption effects in coated metal structures yields the heat equation with piecewise smooth coefficients and a new kind of source term. This term is special, because it is non‐linear and furthermore depends on a time derivative. In our approach we reformulated this as a new problem for the usual heat equation, without source term but with a new non‐linear coefficient. We gave an existence and uniqueness proof for the weak solution of the reformulated problem. To obtain a numerical solution, we developed a semi‐implicit and a fully implicit finite volume method. We compared these two methods theoretically as well as numerically. Finally, as practical application, we simulated the heat conduction in coated aluminum fibers with adsorption in the zeolite coating. Copyright © 2010 John Wiley & Sons, Ltd.
Replication characterization of microribs fabricated by combining ultraprecision machining and microinjection molding
Authors: Yang Can , Li Lei , Huang Hanxiong , Castro Jose M. , Yi Allen Y. 
Published: May 2010

AbstractThis article aims to investigate the effects of five processing parameters and two geometric factors on replication quality of the microribs, as well as determination of the processing condition when different materials were used. Specifically, the considered parameters include barrel temperature, mold temperature, injection velocity, holding pressure, holding time, aspect ratio, and location of the microribs. The experiment results showed a considerable difference in replicated height of molded microribs with polymethylmethacrylate and polypropylene. Among the processing parameters, the barrel temperature and injection velocity significantly affected replication quality, whereas the holding pressure and holding time appeared to have little influence for both materials. The mold temperature was found to be a sensitive parameter only for polymethylmethacrylate. As for geometric factors, both aspect ratio and location of the microribs played important roles in achievable replication. In addition, simulation results showed good prediction on the trend of how process parameters affect replication, with a small amount of over prediction. POLYM. ENG. SCI., 50:2021–2030, 2010. © 2010 Society of Plastics Engineers
Submicron resolution carrier lifetime analysis in silicon with Fano resonances
Authors: Gundel Paul , Schubert Martin C. , Heinz Friedemann D. , Benick Jan , Zizak Ivo , Warta Wilhelm 
Published: May 2010

AbstractDefect rich regions in multicrystalline silicon are investigated by Raman spectroscopy at high and low injection levels. By analyzing the Fano type asymmetry and the spectral position of the first order Raman peak crucial properties such as recombination lifetime, doping density and stress can be extracted simultaneously. Due to the small wavelength of the excitation laser the spatial resolution of these measurements is significantly below 1 µm, which gives new insight into the impact of defects on the carrier recombination lifetime. The results are evaluated by comparing them to micro‐photoluminescence and synchrotron X‐ray fluorescence measurements. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Diameter‐ and Metallicity‐Selective Enrichment of Single‐Walled Carbon Nanotubes Using Polymethacrylates with Pendant Aromatic Functional Groups
Authors: Pan Xiaoyong , Li Lain‐Jong , Chan‐Park Mary B. 
Published: May 2010

AbstractCurrent methods for the synthesis of single‐walled nanotubes (SWNTs) produce mixtures of semiconducting (sem‐) and metallic (met‐) nanotubes. Most approaches to the chemical separation of sem‐/met‐SWNTs are based on small neutral molecules or conjugated aromatic polymers, which characteristically have low separation/dispersion efficiencies or present difficulties in the postseparation removal of the polymer so that the resulting field‐effect transistors (FETs) have poor performance. In this Full Paper, the use of three polymethacrylates with different pendant aromatic functional groups to separate cobalt–molybdenum catalyst (CoMoCAT) SWNTs according to their metallicity and diameters is reported. UV/Vis/NIR spectroscopy indicates that poly(methyl‐methacrylate‐co‐fluorescein‐o‐acrylate) (PMMAFA) and poly(9‐anthracenylmethyl‐methacrylate) (PAMMA) preferentially disperse semiconducting SWNTs while poly(2‐naphthylmethacrylate) (PNMA) preferentially disperses metallic SWNTs, all in dimethylforamide (DMF). Photoluminescence excitation (PLE) spectroscopy indicates that all three polymers preferentially disperse smaller‐diameter SWNTs, particularly those of (6,5) chirality, in DMF. When chloroform is used instead of DMF, the larger‐diameter SWNTs (8,4) and (7,6) are instead selected by PNMA. The solvent effects suggest that diameter selectivity and change of polymer conformation is probably responsible. Change of the polymer fluorescence upon interaction with SWNTs indicates that metallicity selectivity presumably results from the photon‐induced dipole–dipole interaction between polymeric chromophore and SWNTs. Thin‐film FET devices using semiconductor‐enriched solution with PMMAFA have been successfully fabricated and the device performance confirms the sem‐SWNTs enrichment with a highly reproducible on/off ratio of about 103.
Nematic‐like Organization of Magnetic Mesogen‐Hybridized Nanoparticles
Authors: Demortière Arnaud , Buathong Saïwan , Pichon Benoît P. , Panissod Pierre , Guillon Daniel , Bégin‐Colin Sylvie , Donnio Bertrand 
Published: May 2010

AbstractA fluid nematic‐like phase is induced in monodisperse iron oxide nanoparticles with a diameter of 3.3 nm. This supramolecular arrangement is governed by the covalent functionalization of the nanoparticle surface with cyanobiphenyl‐based ligands as mesogenic promoters. The design and synthesis of these hybrid materials and the study of their mesogenic properties are reported. In addition, the modifications of the magnetic properties of the hybridized nanoparticles are investigated as a function of the different grafted ligands. Owing to the rather large interparticular distances (about 7 nm), the dipolar interaction between nanoparticles is shown to play only a minor role. Conversely, the surface magnetic anisotropy of the particles is significantly affected by the surface derivatization.
Synthesis and Some Surface Properties of Glycine‐Based Surfactants
Authors: Mousli Radia , Tazerouti Amel 
Published: May 2010

AbstractA new group of anionic surfactants, namely sodium salts of secondary alkanesulfonamidoacetic acid, were synthesized using n‐alkanesulfonyl chlorides as starting materials. These surfactants, having the formula: R–SO2–NH–CH2–COONa, with R = C12, C14, C16 and C18, were obtained in a simple way with quantitative yields. Different chain lengths and positional isomers of this new type of surfactants are expected to present differences in surface properties and foamability. The surface properties including critical micelle concentrations and minimal surface tensions γmin were determined for each prepared surfactant using surface tension measurements with a Wilhelmy plate. Surface excess and minimum area per molecule at the air–water interface were determined for different concentrations at 25 and 50 °C using the Gibbs equation. The foaming power was also determined by the Bartsch method, and the results obtained were compared to those of a commercial surfactant, the linear alkylbenzenesulfonate. The stability of the foam formed was also evaluated. As expected, these surfactants exhibit good surface properties and show good foaming power.
Brief report: An online support intervention: Perceptions of adolescents with physical disabilities
Authors: Stewart Miriam , Barnfather Alison , Magill‐Evans Joyce , Ray Lynne , Letourneau Nicole 
Published: May 2010

ABSTRACTAdolescents with cerebral palsy and spina bifida report restricted interactions with peers and gaps in social support. A pilot online support intervention offered interactions with peers. Five mentors with cerebral palsy or spina bifida and 22 adolescents with the same disabilities met weekly online for 25 group sessions over six months. Participants completed quantitative measures of loneliness, sense of community, self‐perceptions, coping, and social support prior to intervention, post‐intervention, and delayed post‐intervention. Semi‐structured qualitative interviews elicited perceptions of the intervention's impacts. Participants reported more contact with teens with disabilities, decreased loneliness, and increased social acceptance and confidence. A significant increase in sense of community was reported from post‐intervention to delayed post‐intervention. Encouraging qualitative findings were supported by trends in the quantitative measures. This pilot study can guide a future community‐based intervention trial.
5‐HT2C receptor agonists attenuate pain‐related behaviour in a rat model of trigeminal neuropathic pain
Authors: Nakai Kunihiro , Nakae Aya , Oba Sosuke , Mashimo Takashi , Ueda Koichi 
Published: May 2010

AbstractPeripheral branches of the trigeminal nerve may be damaged during maxillofacial injury or surgical procedures and trigeminal trauma may induce severe pain that is very challenging to treat. Chronic constriction injury to the infraorbital nerve (ION‐CCI) by loose ligatures has proven a useful model for some types of trigeminal neuropathic pain disorder. Using ION‐CCI rats, we examined the antiallodynic effects of intrathecally administered agents which are selective for 5‐HT2C receptors. Allodynia was evaluated by applying von Frey filaments to skin innervated by the injured ION. Dose‐dependent antiallodynic effects followed administration of three 5‐HT2C receptor agonists, 6‐chloro‐2‐(1‐piperazinyl)‐pyrazine (MK212: 10, 30, and 100 μg); (S)‐2‐(chloro‐5‐fluoro‐indol‐l‐yl)‐1‐methyamine fumarate (RO 60‐0175: 10, 30, and 100 μg); (AaR)‐8,9‐dichloro‐2,3,4,4a‐tetrahydro‐1H‐pyrazino[1,2‐a]quinoxalin‐5(6H)‐one (WAY‐161503: 10, 30, and 100 μg). ED50 values for antiallodynic effects of MK212, RO 60‐0175, and WAY‐161503 were 39.62, 46.67, and 51.22 μg, respectively. Intrathecal administration of the 5‐HT2C receptor antagonist, 8‐[5‐2,4‐dimethoxy‐5‐(4‐trifluoromethylphenylsulphonamido)phenyl‐5‐oxopentyl]‐1,3,8‐triazaspiro[4,5]decane‐2,4‐dione (RS‐102221: 30 μg) did not alter the mechanical threshold. Intrathecal pretreatment with RS‐102221 (10 and 30 μg) reduced the antiallodynic effects of the highest dose of 5‐HT2C agonists. These results indicated that, in this rat model, the 5‐HT2C receptor plays a role in spinal inhibition of trigeminal neuropathic pain.
Aleksandr Dugin's Transformation from a Lunatic Fringe Figure into a Mainstream Political Publicist, 1980–1998: A Case Study in the Rise of Late and Post-Soviet Russian Fascism
Authors: Umland Andreas 
Published: May 2010

The paper 1 1 The paper expands on my earlier survey: Toward an Uncivil Society? Contextualizing the Recent Decline of Parties of the Extreme Right Wing in Russia, 2002. On Dugin's fascism, see Griffin, Loh, and Umland (2006); Umland (2006b, 2006c, 2006d), reprinted in: Verkhovskii (2006), and Laruelle (2007). was completed in 2008 and complements previous analyses of post-communist Russian right-wing extremism, in general, and studies of “neo-Eurasianism,” in particular, surveying some circumstances of the emergence of its major ideologist Aleksandr Dugin (b. 1962). It introduces some teachers and collaborators of Dugin who influenced him before he became a known journalist, writer and commentator in the late 1990s. It also sketches some of Dugin's initiatives and activities until he rose to the position of an official advisor to Gennady Seleznev, the Speaker of the State Duma, the lower house of the Russian parliament, in 1998. The footnotes provide a comprehensive bibliography on Western and Russian sources on the Russian “New Right.” It concludes with some suggestion where further research into the Dugin phenomenon could go. Current position Assistant Professor of Contemporary Russian History at The Catholic University of Eichstaett-Ingolstadt, Bavaria, and editor of the book series Soviet and Post-Soviet Politics and Society ( http://www.ibidem-verlag.de/spps.html ), Stuttgart and Hannover. Biographical sketch CertTransl (Leipzig), MA (Stanford), MPhil (Oxford), DipPolSci, DrPhil (FU Berlin), PhD (Cambridge). Visiting fellow at Stanford's Hoover Institution in 1997–1999, and Harvard's Weatherhead Center in 2001–2002. Bosch visiting lecturer at Yekaterinburg's Urals State University in 1999–2001, and Kyiv's Mohyla Academy in 2003/2005. In January-December 2004, temporary lecturer in Russian and East European studies at St. Antony's College Oxford. In 2005–2008, German Academic Exchange Service (DAAD) Lecturer Kyiv's Shevchenko University. Papers in Problems of Post-Communism, East European Jewish Affairs, Osteuropa, Österreichische Zeitschrift für Politikwissenschaft, Politicheskie issledovaniya, European Political Science, Political Studies Review, The Journal of Slavic Military Studies, Voprosy filosofii, Obshchestvennye nauki i sovremennost’, Forum für osteuropäische Ideen- und Zeitgeschichte, Ab Imperio and other journals. Editor of The Implementation of the European Convention on Human Rights in Russia: Philosophical, Legal und Empirical Studies (Stuttgart: Ibidem 2004), Geistes- und Sozialwissenschaftliche Hochschullehre in Osteuropa. Vols. 1, 2, 3 & 4 (Frankfurt a.M. u.a.: Peter Lang 2005, 2006, 2007 & 2009), and, with Roger Griffin and Werner Loh, Fascism Past and Present, West and East: An International Debate on Concepts and Cases in the Comparative Study of the Extreme Right. With an afterword by Walter Laqueur (Stuttgart: Ibidem-Verlag 2006).
Anterior abdominal wall cervicopexy for treatment of stage III and stage IV uterine prolapse
Authors: Salem Hosam T. , Tawfik Reda M. , El Saman Ali M. , Nasr Ahmed 
Published: May 2010

AbstractObjectiveTo study the operative and postoperative outcomes of anterior abdominal wall cervicopexy (AWC) for treatment of stage III and stage IV uterine prolapse.MethodsAWC was performed by anchoring the supravaginal cervix to the anterior abdominal wall. This was done following obliteration of the pouch of Douglas via laparotomy.ResultsAmong 37 patients, AWC was performed in 21 women with stage III and 16 women with stage IV uterine prolapse. Overcorrection was observed in 3 women. Postoperatively, 2 women experienced febrile morbidity and 5 had urinary retention. Thirteen women complained of urinary frequency, but all reported improvement at 3‐month follow up. Among 24 women who became pregnant, 14 delivered vaginally, 5 delivered by cesarean, and 5 had an ongoing pregnancy. Four recurrences occurred: 2 stage II and 2 stage III prolapses. Three of these women had delivered by cesarean, while the fourth recurrence occurred after the patient's third vaginal birth.ConclusionsAWC is a simple and effective procedure to treat stage III and stage IV uterine prolapse. However, some surgical modifications and more studies are required to ascertain its validity.
Cochlear implantation in adolescents with prelinguistic deafness
Authors: Arisi Elena , Forti Stella , Pagani Davide , Todini Loredana , Torretta Sara , Ambrosetti Umberto , Pignataro Lorenzo 
Published: May 2010

ObjectiveThe aims of this study were to examine auditory function in a group of adolescents with prelingual deafness who received cochlear implants (CI) and to identify poor‐outcome predictors in order to define reliable prognostic indicators useful in selecting patients for CI.Study DesignProspective study.SettingThe study was conducted in the Audiology Unit of Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.Subjects and MethodsThe study involved 45 adolescents (mean age at implantation: 13.4 ± 2.6 years, range: 11‐18) with profound congenital hearing impairment with a follow‐up of three years. Preimplantation and postimplantation auditory performance and speech perception were evaluated using the mean score of three hearing and speech perception tests (vowel‐consonant‐vowel [VCV], identification of disyllabic words, and recognition of short sentences) performed in auditory‐only listening conditions.ResultsSignificant improvements in all speech perception tests were observed after CI. However, 15 cases were considered “poor performers” (i.e., the auditory performance of these patients was less than 30 percent). The diagnosis of deafness in these subjects was significantly delayed (18.07 ± 6.25 and 34.4 ± 10.26 months in good and poor performers, respectively, P = 0.006), and their hearing threshold was significantly lower than in the good users group. The mean age at CI was 12.8 ± 2.33 and 14.53 ± 2.70 years in good and poor performers, respectively (P = ns).ConclusionCI was shown to be a useful device with the ability to reverse the adverse consequences of hearing loss, particularly for prelingual adolescents who receive implantation early in life and who present a hearing threshold of 100 dB or better both at diagnosis and at surgery.
A comparison of the reproducibility of verbal and nonverbal facial gestures using three‐dimensional motion analysis
Authors: Popat Hashmat , Henley Emma , Richmond Stephen , Benedikt Lanthao , Marshall David , Rosin Paul L. 
Published: May 2010

ObjectiveTo evaluate the reproducibility of selected verbal and nonverbal facial gestures.Study DesignCross‐sectional study.SettingSchool of Dentistry, Cardiff University, Cardiff, United Kingdom.Subjects and MethodsTwenty‐five white subjects were asked to perform four verbal gestures and two nonverbal facial gestures in a normal, relaxed manner. The sequences were captured using a noninvasive, three‐dimensional motion analysis scanner (3dMDFace Dynamic System; 3Q Technologies, Atlanta, GA) at an initial time point (T1) and one month later (T2). Principal component analysis was used to analyze the dynamics of lip movement, and dynamic time warping was used to evaluate the reproducibility between T1 and T2 for the individual facial gestures. Statistical analyses were used to compare the reproducibility of the different facial gestures.ResultsAll four verbal gestures were found to be significantly more reproducible than the nonverbal gestures. The word “puppy” was most reproducible, and the normal smile expression least reproducible. A hierarchy of reproducibility is proposed as “puppy,” “baby,” “rope,” “bob,” standardized smile, normal smile.ConclusionVerbal facial gestures, in particular the words “puppy” and “baby,” are more appropriate for use in the assessment of lip movement when compared with smile expressions because of their high level of reproducibility over a one‐month period.
Hot saline irrigation for control of intraoperative bleeding in adenoidectomy: A randomized controlled trial
Authors: Özmen Süay , Özmen Ömer Afşın 
Published: May 2010

ObjectiveTo investigate the efficiency of hot (50°C) saline irrigation for hemostasis after adenoidectomy.Study DesignA prospective, controlled, randomized study to investigate hot saline solution in hemostasis of adenoidectomy.SettingA tertiary care pediatric hospital.Subjects and MethodsA group of 120 children, undergoing adenoidectomy alone, were randomized into two groups, either the room‐temperature (25°C) or 50°C saline group, at the start of the operation.ResultsOne hundred and twenty consecutive patients were enrolled in the study. Age ranged from 1.5 to nine years (mean ± SD: 4.5 ± 1.9 years vs 4.9 ± 1.8 years, 25°C vs 50°C saline groups). There were 36 males and 24 females in the control group (25°C saline group), and 30 males and 30 females in the 50°C saline group. Compared to patients in the control group, 50°C saline reduced the operative time by 3.1 minutes (95% confidence interval [CI] 1.79‐4.41, P = 0.001) and reduced the time for hemostasis by 1.77 minutes (95% CI 0.83‐2.70, P = 0.008).ConclusionThe present study demonstrated that the 50°C saline irrigation was more effectual for postadenoidectomy hemostasis in comparison to room‐temperature (25°C) saline irrigation by providing a lesser hemostasis time and requiring lesser need of recurettage and electrocauterization.
No significant ice-sheet expansion beyond present ice margins during the past 4500 yr at Rauer Group, East Antarctica
Authors: Berg Sonja , Wagner Bernd , White Duanne A. , Melles Martin 
Published: May 2010

AbstractThe history of glacial advances and retreats of the East Antarctic ice sheet during the Holocene is not well-known, due to limited field evidence in both the marine and terrestrial realm. A 257-cm-long sediment core was recovered from a marine inlet in the Rauer Group, East Antarctica, 1.8 km in front of the present ice-sheet margin. Radiocarbon dating and lithological characteristics reveal that the core comprises a complete marine record since 4500 yr. A significant ice-sheet expansion beyond present ice margins therefore did not occur during this period.