bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopically Assisted Tunnel Approach for Minimally Invasive Corticotomies: A Preliminary Report
Authors: Hernández‐Alfaro Federico , Guijarro‐Martínez Raquel 
Published: September 2011

Background: The dental community has expressed low acceptance of traditional corticotomy techniques for corticotomy‐facilitated orthodontics. These procedures are time consuming, entail substantial postoperative morbidity and periodontal risks, and are often perceived as highly invasive.Methods: A total of 114 interdental sites were treated in nine consecutive patients. Under local anesthesia, a tunnel approach requiring one to three vertical incisions per arch (depending on the targeted teeth) was used. Piezosurgical corticotomies and elective bone augmentation procedures were performed under endoscopic assistance. Postoperative cone‐beam computerized tomography evaluation was used to confirm adequate corticotomy depth.Results: Procedures were completed in a mean time of 26 minutes. Follow‐up evaluations revealed no loss of tooth vitality, no changes in periodontal probing depth, good preservation of the papillae, and no gingival recession. No evidence of crestal bone height reduction or apical root resorption was detected.Conclusions: The tunnel approach minimizes soft‐tissue debridement and permits effective cortical cuts. The combination of piezosurgery technique with endoscopic assistance provides a quick, reliable means to design and perform these corticotomies while maximizing root integrity preservation. Moreover, the sites needing bone augmentation are selected under direct vision. Compared to traditional corticotomies, this procedure has manifest advantages in surgical time, technical complexity, patient morbidity, and periodontium preservation.
Data Comparison Between Two Dental Spectrophotometers
Authors: Khashayar G , Dozic A , Kleverlaan CJ , Feilzer AJ 
Published: September 2011

Clinical Relevance
Different color measuring devices (CMDs) are used to determine tooth color and the color of the matching restoration during the manufacturing process. This study questions whether it is possible to communicate color accurately when dentists and dental laboratories use different CMDs at different locations.
Influence of ThO2 on the photocatalytic activity of TiO2
Authors: Kralchevska Radina , Milanova Maria , Kovacheva Petya , Kolev Jovo , Avdeev Georgi , Todorovsky Dimitar 
Published: September 2011

AbstractMicrocomposites consisting of TiO2 (or Ce-doped TiO2) and ThO2 (0.5–2% of the TiO2 mass) are produced by sol-gel synthesis of TiO2 in presence of ThO2. X-ray diffraction study reveals the effects of ThO2 (compared to the ThO2-free TiO2, obtained by the same method) on the anatase interplanar distances, crystallites size and phase composition. The photocatalytic tests in presence of the composites under UV irradiation reveal an increase of the Malachite Green degradation rate constant. The effect depends on the Th relative content, temperature of annealing of the catalyst and addition of other doping agent. The highest photocatalytic activity is observed for TiO2 obtained at 550°C and containing 1% ThO2. The composite exhibits activity in dark, also. The presence of Ce4+ ions is not an obligatory requirement for the realization of the ThO2 effect. The reported results suggest that the radioactivity of the Th and/or its decay products is one of the main factors responsible for the increased photocatalytic activity of TiO2.
Simple method of fabrication of hydrophobic coatings for polyurethanes
Authors: Butruk Beata , Ziętek Paulina , Ciach Tomasz 
Published: September 2011

AbstractThe aim of this study was to develop a method of manufacturing versatile hydrophobic coatings for polymers. Authors present a simple technique of polyurethane (PU) surface modification with covalently attached silicones (PDMS) or fluorocarbons (PFC). Diisocyanates were applied as linker molecules. The obtained coatings were characterized using spectroscopic analysis (FTIR), scanning acoustic microscopy (SAM) and water contact angle measurements. FTIR analysis revealed high efficiency of grafting reaction. The results of contact angle measurement indicated significant increase of hydrophobicity — from 66° (unmodified PU) to 113° (PU grafted with PDMS) and 118° (PU grafted with PFC). Acoustic microscopy analysis confirmed satisfactory homogeneity and smoothness of the fabricated layers. In vitro cell tests revealed non-adherent properties of the surfaces. Both, MTT assay and fluorescence staining confirmed non-cytotoxicity of the coatings, which makes them potential candidates for use in biomedical applications.
NSGA-II-RJG applied to multi-objective optimization of polymeric nanoparticles synthesis with silicone surfactants
Authors: Furtuna Renata , Curteanu Silvia , Racles Carmen 
Published: September 2011

AbstractPolydimethylsiloxane nanoparticles were obtained by nanoprecipitation, using a siloxane surfactant as stabilizer. Two neural networks and a genetic algorithm were used to optimize this process, by minimizing the particle diameter and the polydispersity, finding in this way the optimum values for surfactant and polymer concentrations, and storage temperature. In order to improve the performance of the non-dominated sorting genetic algorithm, NSGA-II, a genetic operator was introduced in this study — the transposition operator — “real jumping genes”, resulting NSGA-II-RJG. It was implemented in original software and was applied to the multi-objective optimization of the polymeric nanoparticles synthesis with silicone surfactants. The multi-objective function of the algorithm included two fitness functions. One fitness function was calculated with a neural network modelling the variation of the particle diameter on the surfactant concentration, polymer concentration, and storage temperature, and the other was computed by a neural network modelling the dependence of polydispersity index on surfactant and polymer concentrations. The performance of the software program that implemented NSGA-II-RJG was highlighted by comparing it with the software implementation of NSGA-II. The results obtained from simulations showed that NSGA-II-RJG is able to find non-dominated solutions with a greater diversity and a faster convergence time than NSGA-II.
The structural, magnetic, hydrogenation and electrode properties of REMg2Cu9−xNix alloys (RE=La, Pr,Tb)
Authors: Pavlyuk Volodymyr , Rozycka-Sokolowska Ewa , Marciniak Bernard , Paul-Boncour Valerie , Dorogova Maria 
Published: September 2011

AbstractThe LaMg2Cu9, PrMg2Cu9, LaMg2Cu4Ni5, PrMg2Cu4Ni5 and TbMg2Cu6Ni3 alloys were prepared for the investigations of crystal structure, magnetic and hydrogen storage properties. The magnetic properties of several REMg2Cu9−xNix compounds have been studied up to 9 T and from 2 to 300 K. Tb compounds show a ferrimagnetic (with Ni) or antiferromagnetic (without Ni) behaviour, which can be attributed to the Tb magnetic structure. At high temperature a paramagnetic Curie Weiss behaviour is observed and the effective moment corresponds to that of Tb. A magnetic contribution of Pr moment is observed in both Pr compounds, with larger magnetization for PrMg2Cu4Ni5 and a transition at 3 K. The hydrogen absorption occurs at 95 bar for LaMg2Cu9 (3 H f.u.−1) and above 2 bars for LaMg2Cu4Ni5 (1.6 H f.u.−1). The effect of Cu-Ni substitution on the electrochemical properties of LaMg2M9 ternary alloys was investigated leading to maximum discharge capacity of 250–310 mAh g−1.
Ternary ion-association complexes between the indium(III) - 4-(2-pyridylazo)resorcinol anionic chelate and some tetrazolium cations
Authors: Toncheva Galya , Gavazov Kiril , Lekova Vanya , Stojnova Kirila , Dimitrov Atanas 
Published: September 2011

AbstractComplex formation and liquid-liquid extraction were studied in systems containing indium(III), 4-(2-pyridylazo)resorcinol (PAR), tetrazolium salt (TZS), water and chloroform. Two different TZS were used: 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT). The optimum conditions for extraction of In(III) as a ternary complex, (TT+)[In(PAR)2] or (MTT+)[In(PAR)2], were found: pH, extraction time, concentration of PAR and concentration of TZS. The constants of extraction (Kex), constants of association (β), constants of distribution (KD) and recovery factors (R%) were determined. The apparent molar absorptivities in chloroform were calculated to be ɛ′520=6.6×104 L mol−1 cm−1 and ɛ′515=7.1×104 L mol−1 cm−1 for the systems with TTC (I) and MTT (II), respectively. Beer’s law was obeyed for In(III) concentrations up to 3.4 µg mL−1 in both the cases. The limits of detection (LOD=0.07 µg mL−1I and LOD=0.12 µg mL−1II), limits of quantification (LOQ=0.24 µg mL−1I and LOQ=0.41 µg mL−1II) and Sandell’s sensitivities (SS) were estimated as well.
Large transverse momentum lepton pair production at the Large Hadron Collider
Authors: Yin Rui-tao , Fu Yong-ping , Li Yun-de 
Published: September 2011

Abstract
We study the large transverse momentum distribution of lepton pairs produced in heavy-ion collisions, making use of the perturbative QCD. Referring to the calculation of the parton-parton production process into lepton pairs at the Relativistic Heavy Ion Collider (RHIC), the production of lepton pairs at large transverse momentum is extended to the Large Hadron Collider (LHC). The contribution of the parton-parton production process into lepton pairs in Pb-Pb collisions at the LHC is calculated, including the complete processes at large transverse momentum. Lepton pair production with the direct single photon process and the resolved single photon process are considered and confirmed to be significant at the LHC.
Preliminary spectroscopic investigation of tacrolimus TiO2 system
Authors: Todica Mihai , Udrescu Luciana 
Published: September 2011

Abstract
The effect of air and UV exposure on the tacrolimus was observed by Raman and UV VIS spectroscopy. For moderate time exposure the chemical structure of tacrolimus is not affected. The absorption property of tacrolimus was enhanced by addition of TiO2.
Three-Dimensional Computed Tomography Analysis to Help Define an Endoscopic Endonasal Approach of the Pterygopalatine Fossa
Authors: Hwang Se Hwan , Joo Young Hoon , Seo Jae Hyun , Kim Soo Whan , Cho Jin Hee , Kang Jun Myung 
Published: September 2011

Background The pterygopalatine fossa (PPF) can be entered endoscopically, but the endoscopic landmarks to localize the bony structures in the PPF are not well described. This study aimed to investigate the anatomy of the sphenopalatine foramen (SPF), vidian canal (VC), and foramen rotundum (FR) with regard to an endoscopic endonasal approach to the PPF using three-dimensional reconstruction of computed tomography (CT) scans. Methods The CT scans of 98 patients were retrospectively evaluated. The morphology of the SPF, VC, and FR as well as the spatial relationship between the SPF and VC were measured on a three-dimensional model. Results The mean diameters of the SPF, VC, and FR were 5.3 ±1.3 mm, 2.4 ± 0.7 mm, and 2.8 ± 0.5 mm, respectively. The mean distance between the VC and posteroinferior margin of SPF was 3.8 ± 1.0 mm. The mean vertical and horizontal distances on the surface plane of sphenoid bone between the VC and FR were 5.8 ± 1.9 mm and 8.5 ± 1.9 mm, respectively. The whole or partial margin of the VC was above the inferior margin of the SPF in 92% (180/196) of the VC and lateral to the posterior margin of the SPF in 98% (195/196) of the VC. The distance between the VC and SPF had a positive correlation with the distances between the VC and FR. Conclusion The endoscopic endonasal approach to the PPF will be performed with greater accuracy and safety through comprehension of the spatial relationships between the SPF, VC, and FR.
Histological Features of the Nasal Mucosa in Hematopoietic Stem Cell Transplantation
Authors: Ortiz Érica , Sakano Eulália , Meirelles Luciana R. , Vigorito Afonso C. , Cintra Maria L. , Paschoal Ilma A. , Chone Carlos T. 
Published: September 2011

Background Immunosuppression is the leading cause of recurrent sinus infections after hematopoietic stem cell transplant (HSCT), with increased incidence of sinusitis in patients with chronic graft versus host disease (GVHD). Histological descriptions of the oral mucosa, lung ciliary epithelium, and intestinal mucosa related to HSCT have been described. However, few have described the nasal mucosa. We, therefore, sought to elucidate the histological and ultrastructural features of the nasal mucosa in patients after HSCT to better understand the pathophysiology of the immune response. Methods Uncinate processes from 24 HSCT patients and 12 immunocompetent patients were subjected to histological analyses via light and transmission electron microscopy (TEM). Results TEM revealed aberrant cilia structure, altered mitochondria quantity, microvilli, and cytoplasm vacuolization. All HSCT patients with rhinosinusitis had significant loss or absence of cilia (p = 0.018). Apoptotic bodies were increased and Goblet cells decreased in nasal epithelium from patients with chronic GVHD (p = 0.04). Conclusion This tissue destruction likely enhances pathogen penetration resulting in recurrent infection.
Functional and Cosmetic Outcomes of External Approach Septoplasty
Authors: Phillips P. Seamus , Stow Nicholas , Timperley Daniel G. , Sacks Raymond , Srubiski Aviva , Harvey Richard J. , Marcells George N. 
Published: September 2011

Background The external approach for septoplasty is an important surgical technique to manage severe septal deviations, caudal deformities, and mid-dorsal abnormalities when a simple endonasal approach may not suffice. The procedure is longer in duration and draws on more resources than endonasal septoplasty. The outcome reporting of the external approach for septoplasty is important to provide evidence of benefit for both patients and health care providers. This study was designed to describe functional and cosmetic outcomes of the external approach for septoplasty. Methods A prospective assessment of consecutive patients undergoing the external approach for septoplasty at a tertiary center was performed. Pre- and postoperative nasal peak inspiratory flow (NPIF), symptom scores, 22-Item Sinonasal Outcome Test (SNOT-22), Nasal Obstruction Score, and Short Form 36 (SF-36) quality-of-life scores were assessed. A global Likert change scale was also used for both function and cosmesis. Results Thirty patients (mean age, 40 ± 15.9 years; 40% women) were assessed with a mean follow-up of 12.2 ± 9.5 months. Mean NPIF improved significantly from 93.3 ± 34.7 to 143.0 ± 44.3 (p < 0.001). Nasal obstruction score improved significantly from 3.6 ± 1.3 to 0.69 ± 1.2 (p < 0.001). SNOT-22 improved significantly from 34.1 ± 17.2 to 12.7 ± 14.9 (p < 0.001). Ninety-six percent had subjective improvement in nasal function, and 96% had no change or improvement in cosmesis. Seventy percent improved by the minimal clinically important difference for NPIF. Conclusion The external approach for septoplasty is an operation that produces significant improvements in subjective and objective nasal health measures. Although requiring greater training and operative time, it is an appropriate approach for the severely deviated nasal septum.
The Expression of Adiponectin Receptor is Altered in Mild and Moderate/Severe Persistent Allergic Nasal Mucosa
Authors: Kim Ha Kyun , Kim Tae Hoon , Kim Ki Hyoung , Hwang Jae Woong , Park Sang Heon , Yum Gun Whee , Lee Jae Yong , Cho Woo Sung , Lee Heung Man , Lee Seung Hoon , Lee Sang Hag 
Published: September 2011

Background Adiponectin, one of the adipokines, has been implicated in the inflammatory process in patients with allergic rhinitis. The level of adiponectin is affected by immunotherapy. Considering the fact that adiponectin receptors (AdipoRs) mediate intracellular signaling events in response to the binding of adiponectin, the role of AdipoRs in healthy and allergic nasal mucosa should be determined. This study investigates the level of expression and distribution pattern of AdipoR1 and AdipoR2 in healthy, mild, and moderate/severe persistent allergic nasal mucosa to understand the role of adiponectin in allergic rhinitis. Methods The level of expression and distribution pattern of AdipoR1 and AdipoR2 were evaluated in healthy, mild, and moderate/severe persistent allergic nasal mucosa, using semiquantitative reverse-transcriptase–polymerase chain reaction (RT-PCR), immunohistochemistry, and Western blot analysis. Results AdipoR1 was expressed in healthy, mild, and moderate/severe persistent allergic nasal mucosa where it was commonly localized to the vascular endothelium. However, AdipoR2 was not expressed in any samples of nasal mucosa tested in the present study. Semiquantitative RT-PCR and Western blot analysis showed that the level of expression of AdipoR1 mRNA and protein was decreased in mild and moderate/severe persistent allergic nasal mucosa in comparison with healthy nasal mucosa, but not significantly different between mild and moderate/severe persistent allergic nasal mucosa. Conclusion These results indicate that AdipoR1 may play an important role in the pathogenesis of allergic nasal mucosa, suggesting a role for AdipoR1 in vascular dysfunction in mild and moderate/severe persistent allergic nasal mucosa.
Spirometric Abnormalities in Patients with Allergic Rhinitis: Indicator of an “Asthma March”?
Authors: Ciprandi Giorgio , Signori Alessio , Tosca Maria Angela , Cirillo Ignazio 
Published: September 2011

Background Allergic rhinitis (AR) may precede and promote the onset of asthma. However, few studies addressed this issue mainly concerning bronchial physiological parameters. The aim of this study was to assess forced expiratory flow at 25–75% (FEF 25–75 ), forced expiratory volume at 1 second (FEV 1 ), and response to bronchodilation test in a large group of AR patients. Methods Sixteen hundred five adult AR patients were evaluated. Clinical examination, assessment of nasal obstruction perception by visual analog scale, spirometry, and bronchodilation test were performed in all patients. Results There were 8.4% of patients with abnormal FEV 1 values, 24.7% had impaired FEF 25–75, and 66.1% had reversibility with bronchodilation. A trend of spirometric impairment seems to exist in these patients. Age, gender, and duration of rhinitis may be risk factors for these findings. Different grades of bronchial impairment seem to exist. Conclusion This study highlights the close link between upper and lower airways and suggests the possible existence of a progression from AR toward asthma, such as an “asthma march.” Therefore, asthma should be suspected and carefully investigated in AR patients.
Intraoperative Medialization of Medial Rectus Muscle as a New Endoscopic Technique for Approaching Intraconal Lesions
Authors: Tomazic Peter Valentin , Stammberger Heinz , Habermann Walter , Gerstenberger Claus , Braun Hannes , Gellner Verena , Mokry Michael , Klein Angelika , Langmann Gerald , Köele Wolfgang 
Published: September 2011

Background Intraconal tumors of the orbit are rare entities and surgical treatment is challenging. Endoscopic transnasal approaches to the orbit offer a new perspective for surgery, although only few reports exist in literature. This study displays the Graz experience with endoscopic approaches to intraorbital tumors between 2006 and 2010 introducing a novel endoscopic technique for temporary medialization of the medial rectus muscle facilitating access to the orbital cone. Methods A retrospective analysis of patients’ charts was performed. Results For approaches to intraconal lesions a special endoscopic temporary medialization technique of the medial rectus muscle through applying transseptal sutures was developed. Six patients (four male and two female patients) have been included in this study presenting with intraconal/intraorbital tumors. Three patients underwent endoscopic surgery for two hemangiomas and one Schwannoma, respectively, and three patients were successfully biopsied endoscopically revealing one malignant melanoma, one malignant lymphoma, and one optic glioma each. Both hemangiomas were completely resected without any deterioration of vision. The Schwannoma was partially resected with postoperative imaging showing no tumor progression within 3 months. No intraoperative complications occurred. Five cases were performed with computer assisted surgery using CT/MR fusion navigation. Conclusion Although technically challenging, the endoscopic approach to the orbit, even for intraconal lesions with medialization of the medial rectus muscle, can be safe and promising for well-selected cases. Good postoperative results and sufficient material acquisition for proper histological examination can be obtained. Advantages are good visualization of the surgical field and avoidance of external scars. Limitations to endoscopic techniques are tumors in the lateral superior and lateral inferior quadrant of the orbit.
The Canine Fossa Puncture Technique in Chronic Odontogenic Maxillary Sinusitis
Authors: Albu Silviu , Baciut Mihaela , Opincariu Iulian , Rotaru Horatiu , Dinu Cristian 
Published: September 2011

Background Endoscopic sinus surgery (ESS) including middle meatus antrostomy (MMA) has been advocated as the technique of choice in the treatment of maxillary chronic odontogenic sinusitis (COS). However, recently the endoscopic canine fossa puncture (CFP) has been proposed as an alternative surgical technique of accessing the entire antrum when pathology is limited only to the maxillary sinus. This study was designed to assess the outcomes of the CFP approach versus ESS (comprising MMA) in the management of COS. Methods A prospective study was performed on patients with COS produced by odontogenic infections (periapical granulomas or small inflammatory cysts of the molars or bicuspids), oroantral fistula (OAF), large odontogenic cysts, and maxillary foreign bodies (dental fillings, teeth roots, and implants). Patients were randomly allocated into two groups: 56 patients underwent CFP and in 54 patients the maxillary sinus was approached through MMA. After a mean follow-up of 18.5 months, recurrence rates were compared between the two groups. Results During the follow-up period, OAF recurred in 10 patients: 4 in the MMA group (7.4%) and 6 in the CFP group (10.7%). The difference is not statistically significant (p = 0.39, Fisher exact test). Conclusion In patients with COS a conservative approach with avoidance of endonasal surgery is suggested: in COS without a fistula, CFP at the time of dental treatment will be sufficient. In OAF cases, CFP yielded similar results with MMA. Nevertheless, additional study with a larger sample and a longer follow-up is required to validate these results.
Pathophysiology of Chronic Rhinosinusitis with Nasal Polyp
Authors: Hsu Joy , Peters Anju T. 
Published: September 2011

Background Chronic rhinosinusitis (CRS) is a common inflammatory condition of the paranasal sinuses and nasal passages. CRS with nasal polyp (CRSwNP) is a subtype of CRS, and the pathogenesis of CRSwNP remains largely unclear. Methods This article reviews the literature regarding the pathophysiology of CRSwNP. Results Evidence suggests that altered innate immunity, adaptive immunity, tissue remodeling, and/or effects of microorganisms may play a role in the development of CRSwNP. Aberrant arachidonic acid metabolism may also contribute to the pathogenesis of CRSwNP in patients with aspirin-exacerbated respiratory disease. Conclusion There have been significant advances in the understanding pathophysiology of CRSwNP. Additional research is needed to elucidate these mechanisms and to determine their relative importance in the pathogenesis of CRSwNP.