bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual art in hospitals: case studies and review of the evidence
Authors: Lankston Louise , Cusack Pearce , Fremantle Chris , Isles Chris 
Published: December 2010

Summary In 2006 a Department of Health Working Group on Arts and Health reported that the arts have ‘a clear contribution to make and offer major opportunities in the delivery of better health, wellbeing and improved experience for patients, service users and staff alike’. In this review we examine the evidence underpinning this statement and evaluate the visual art of three of Scotland's newest hospitals: the Royal Infirmary of Edinburgh, the new Stobhill Hospital, and the new Victoria Infirmary in Glasgow. We conclude that art in hospitals is generally viewed positively by both patients and staff, but that the quality of the evidence is not uniformly high. Effects may be mediated by psychological responses to colour hue, brightness and saturation. Colours that elicit high levels of pleasure with low levels of arousal are most likely to induce a state of calm, while those causing displeasure and high levels of arousal may provoke anxiety. The fact that patients frequently express a preference for landscape and nature scenes is consistent with this observation and with evolutionary psychological theories which predict positive emotional responses to flourishing natural environments. Contrary to a view which may prevail among some contemporary artists, patients who are ill or stressed about their health may not always be comforted by abstract art, preferring the positive distraction and state of calm created by the blues and greens of landscape and nature scenes instead.
Personalized Medicine in Diabetes
Authors: Malandrino Noemi , Smith Robert J 
Published: December 2010

BACKGROUNDMultiple genes that are associated with the risk of developing diabetes or the risk of diabetes complications have been identified by candidate gene analysis and genomewide scanning. These molecular markers, together with clinical data and findings from proteomics, metabolomics, pharmacogenetics, and other methods, lead to a consideration of the extent to which personalized approaches can be applied to the treatment of diabetes mellitus.CONTENTKnown genes that cause monogenic subtypes of diabetes are reviewed, and several examples are discussed in which the genotype of an individual with diabetes can direct considerations of preferred choices for glycemic therapy. The extent of characterization of polygenic determinants of type 1 and type 2 diabetes is summarized, and the potential for using this information in personalized management of glycemia and complications in diabetes is discussed. The application and current limitations of proteomic and metabolomic methods in elucidating diabetes heterogeneity is reviewed.SUMMARYThere is established heterogeneity in the determinants of diabetes and the risk of diabetes complications. Understanding the basis of this heterogeneity provides an opportunity for personalizing prevention and treatment strategies according to individual patient clinical and molecular characteristics. There is evidence-based support for benefits from a personalized approach to diabetes care in patients with certain monogenic forms of diabetes. It is anticipated that strategies for individualized treatment decisions in the more common forms of diabetes will emerge with expanding knowledge of polygenic factors and other molecular determinants of disease.
Non-infectious conditions and gestational age influence C-reactive protein values in newborns during the first 3 days of life
Authors: Hofer Nora , Müller Wilhelm , Resch Bernhard 
Published: December 2010

AbstractBackground: Our aim was to analyze C-reactive protein (CRP) values in term and preterm infants and correlate non-infection-associated increases with various neonatal disorders.Methods: Retrospective cohort study that included all newborns hospitalized at a tertiary care center between 2004 and 2007 with documented CRP values in the first 3 days of life. Analysis of differences in CRP values between term and preterm newborns and cases with CRP increases in sepsis negative newborns.Results: For diagnosis of blood culture proven sepsis (19 and 14 cases, respectively) in 353 preterm and 179 term newborns, CRP at a cut-off of 8 mg/L had sensitivities of 53% and 86% and specificities of 91% and 88%, respectively. The area under the receiver operating characteristics curves were 0.799 and 0.890, respectively. Preterm newborns had lower median values compared to term newborns in sepsis positive (9 vs. 18.5 mg/L, p<0.001) and negative newborns (0.5 vs. 2 mg/L, p<0.001). Increases in individuals without infection were correlated significantly with meconium aspiration syndrome and surfactant application in term newborns (p=0.009 and 0.025, respectively) and with surfactant application and higher birth weight in preterm newborns (p<0.001 and 0.031, respectively).Conclusions: CRP values were significantly lower in preterm compared to term newborns, and its application in the diagnosis of sepsis in preterm newborns was not as reliable as in term newborns. Meconium aspiration syndrome, surfactant application, and high birth weight were associated significantly with increased CRP values.
Words Spoken by Osiris or the Ibis? An Ibis Coffin with a Hieroglyphic Inscription in the Macquarie University Museum of Ancient Cultures
Authors: Coussement Sandra , Depauw Mark 
Published: December 2010

Abstract
The article discusses an unprovenanced Ptolemaic lid of an ibis coffin from the collection of the Macquarie University Museum of Ancient Cultures (Sydney). Various aspects suggest that it originates from the ibis cemetery in Tuna El-Gebel. The lid bears a demotic and a hieroglyphic inscription, which are both transliterated, translated and provided with detailed commentary. The demotic inscription includes the usual practical information but the hieroglyphic text is exceptional. It contains the first part of chapter 72 of the Book of the Dead. So far, no other ibis coffin with a similar hieroglyphic text is known. Special attention goes to the peculiar introduction of the chapter on this lid, leaving it unclear who should utter the words following Dd mdw jn, or on whose behalf.
Theben-Ost III. Dritter Teil1: Zehn inj-Tempel-Quittungen (Nr. 47-56), eine Brief-Quittung über Smw und Hw-aHwtj (Nr. 57), zwei Abkommen über Acker-Pacht (Nr. 58, 58A), sechs (staatliche) Acker-Amt-Quittungen2 (Nr. 59-64), die drei mir bekannten (staatlichen) i.ir.ir-iw-Quittungen (Nr. 65-67), das Akten-Fragment aus der Öl-Mühle (des Tempels?) (Nr. 68) und Indices
Authors: Kaplony-Heckel Ursula 
Published: December 2010

Abstract
The 23 Demotic Ostraca of the Third Part of Theben-Ost III all come from the Theban area. They have some peculiarities: In No. 47, 48, 51, 55, 56 one finds percents; No. 48, 51, 52, 53, 54 are syntaxis receipts of the temple; No. 49 notes the bakshish [of the temple scribe]; No. 57 is a letter receipt of tax-free land of Djême; No. 58, 58A are two fragmentary early Roman land leases of temple land, noting the “one aroura for the Pharao”; No. 50 Recto and Verso contains a temple receipt, starting with “Copy of the income” (Xt pA iw). The receipts for labour (r.rx=w) No. 59, 60, 64 from Western Thebes, and No. 62 from Eastern Thebes, are issued by the state, No. 61 by the temple. The difficult No. 63 may be an abbreviated r.rx=w Text. No. 65, 66, 67 show a rare receipt type i.ir.ir-iw, issued by the state (?). The very fragmentary oil seed notes No. 68 presents i.a. a list of Eastern Theban land names.
Traces of a Stative-Eventive Opposition in Ancient Egyptian. Rethinking Pseudoparticiple as Old Perfective
Authors: Oréal Elsa 
Published: December 2010

Abstract
Challenging the usual semantic characterisation of the “adjectival” or nfr sw predication, this paper shows that it originally functioned as a non-eventive, stative (vs. dynamic) predication rather than as an essential (vs. contigent) predication. Conversely, the traditional characterisation of the Pseudoparticiple with statal verbs as an alleged stative will be questioned. This study thus claims that the Pseudoparticiple was initially a V-S periphrastic conjugation specialized for dynamical/eventive predication, forming one and the same paradigm with the Old Perfective sDm + lexical subject (which is not a sDm=f). The real “stative” counterpart to this re-united Old Perfective paradigm appears to be the nfr sw predication. From a typological point of view, this suggests that the opposition between event and state may have played a crucial role in the Proto-Egyptian verbal system.
Trigeminal neuralgia in young adults
Authors: Bahgat Diaa , Ray Dibyendu K. , Raslan Ahmed M. , McCartney Shirley , Burchiel Kim J. 
Published: December 2010

Object
Trigeminal neuralgia (TN) is a form of facial pain that can be debilitating if left untreated. It typically affects elderly adults and is thought to be related to neurovascular compression. It is uncommon in people younger than 30 years of age, with only 1% of cases reportedly occurring in those younger than 20 years of age. The most common cause of compression in young adults is thought to be venous nerve compression either alone or in association with arterial nerve compression. The objective of this study was to review data in cases of TN in which patients were 25 years of age or younger and to identify TN disease characteristics, demographics, clinical features, operative findings, and outcome.

Methods
The authors retrospectively reviewed the clinical records, surgical treatment, and long-term outcome in patients 25 years of age or younger with TN who underwent surgery performed by the senior author (K.J.B.) at Oregon Health & Science University between 1995 and 2008.

Results
Seven patients (2 males and 5 females) met the inclusion criteria. The average age at symptom onset was 19.6 ± 3.4 years (± SD) and the average age at surgery was 22.9 ± 1.7 years. Six patients had right-sided symptoms and 1 had left-sided symptoms. Pain distribution was the V2 in 3 cases, V2–3 in 3 cases, and V3 in 1 case, with no cases of V1 affliction. A total of 11 procedures were performed in 7 patients, and 4 patients underwent a second procedure. Surgery and imaging revealed venous compression in all cases. The average follow-up period was 35.5 ± 39.9 months (median 12 months). Three patients reported a good outcome (no pain with or without medications) and 4 reported a poor outcome (either no pain relief or mild pain relief after surgery).

Conclusions
Trigeminal neuralgia is uncommon in young adults. Patients tend to present with symptoms similar to those in adults: long periods of pain and venous compression, but outcome unfortunately is not as good as that reported in the older population.
Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice
Authors: Chen Lifen , Zhang Xuefeng , Chen-Roetling Jing , Regan Raymond F. 
Published: December 2010

Object
Heme toxicity may contribute to the pathogenesis of intracerebral hemorrhage (ICH). The primary defense against extracellular heme is provided by hemopexin, a serum and neuronal glycoprotein that binds it with very high affinity and mitigates its prooxidant effect. In the present study, the authors tested the hypothesis that hemopexin knockout mice would sustain more injury after experimental ICH than their wild-type counterparts.

Methods:
Striatal ICH was induced by the stereotactic injection of bacterial collagenase or autologous blood. Three days later, striatal protein oxidation was assessed via carbonyl assay. Cell viability was quantified at 8–9 days by using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Behavioral deficits were detected with high-resolution digital analysis of 6-hour home cage video recordings and standard testing.

Results:
Perihematomal protein oxidation was increased in wild-type collagenase-injected striata by approximately 2.1-fold, as compared with contralateral striata; protein carbonyls were increased 3-fold in knockout mice. Striatal cell viability was reduced by collagenase injection in wild-type mice to 52.9 ± 6.5% of that in the contralateral striata, and to 31.1 ± 3.7% of that in the contralateral striata in knockout mice; similar results were obtained after blood injection. Digital analysis of 6-hour video recordings demonstrated an activity deficit in both models that was significantly exacerbated at 8 days in knockout mice. Striatal heme content 9 days after blood injection was increased approximately 2.7-fold in knockouts as compared with wild-type mice.

Conclusions:
These results suggest that hemopexin has a protective effect against hemorrhagic CNS injuries. Hemopexin deficiency, which is often associated with sickle cell disease, may worsen outcome after ICH.
Het waterwegennet ten Noord-Oosten van Brugge in de XIIIe eeuw (slot)
Authors: De Smet Antoine 
Published: December 2010

Gilliodts van Severen qui le premier a étudié le réseau hydrographique au Ν. Ε. de Bruges en utilisant des documents qui pouvaient lui permettre d'y voir clair, n'a fait qu'embrouiller la question. Il a voulu soutenir de toutes façons qu'il n'y avait qu'une seule branche, allant de Bruges par Damme, Monike- rede, Hoeke, Mude et l'Écluse à la mer, et qui s'appelait toute entière le Zwin. C'est ainsi qu'il a inventé de toute pièces que la Reie était un canal creusé au xme siècle, et que l'Oude Zwin n'était que l'ancien lit du Zwin.
Nous basant sur les plus anciens textes, les meilleurs textes postérieurs — parmi lesquels nous citons les ommeloopers (terriers), espèces de registres cadastraux des wateringues ou des possessions d'un établissement religieux — et les anciennes cartes, nous avons réétudié la question et nous sommes parvenu à déterminer avec assez bien de précision, l'état de ce réseau hydrographique au N. E. de Bruges au xme siècle, de sorte que nous avons pu tout indiquer sur la carte topographique actuelle de la Belgique au 1 /20.000e, et sur une carte faite d'après la carte topographique au 1 /40.000e, jointe au présent travail.
Il se composait essentiellement de trois cours d'eau principaux formant deux grandes branches, dont l'une se jetait dans l'autre vers la fin du parcours de celle ci. Ces deux branches principales étaient reliées entre elles par trois cours d'eau secondaires.
Assessing Pharmacists' Attitudes regarding Delivery of the Pandemic Influenza Vaccine in British Columbia
Authors: Marra Fawziah , Kaczorowski Janusz A. , Marra Carlo 
Published: December 2010

Background: In response to the clear indication that the second wave of the pandemic (H1N1) 2009 would arrive in North America during fall 2009, the Ministry of Health Services in British Columbia proposed expanding pharmacists' scope of practice to include administering vaccinations. This change in regulations was prompted by the anticipated need to provide millions of doses of the pandemic (H1N1) influenza vaccine in a short period of time. Objectives: To determine pharmacists' willingness and preparedness to deliver vaccines, especially the pandemic (H1N1) influenza vaccine, as well as their preferences related to providing this service. Methods: A survey was developed to elicit pharmacists' opinions concerning administration of vaccines. Staff pharmacists and pharmacy managers and owners licensed to practice in British Columbia were invited to complete the online survey. The survey results were analyzed descriptively. Results: In total, 151 pharmacists participated in the study. The majority of respondents were men (84 [55.6%]) and most had practised for at least 5 years (108 [71.5%]). Most respondents (123 [81.5%]) were interested in administering vaccines to their clients, including the pandemic (H1N1) influenza vaccine (113 [74.8%]). In general, respondents preferred to vaccinate adults rather than children and understood the importance of documentation, reporting of adverse events and reporting to their local health authorities. More than half of participants (84 [55.6%]) felt that they were prepared to provide vaccine services in time for the pandemic (H1N1) vaccination program in fall 2009. The majority of these were prepared to offer vaccination services during daytime hours (91 [74.0%]), and some were willing to do so during the evenings (43 [35.0%]) and on weekends (40 [32.5%]). Ninety (73.2%) of the participants thought they had adequate space to administer vaccinations and maintain patient confidentiality and 111 (90.2%) indicated that they had adequate space to store the vaccines in their refrigerators, but only 82 (66.7%) had adequate storage space in their freezers. Conclusion: Pharmacists in British Columbia were willing to offer vaccination services to their clients. Given this willingness and a general level of preparedness, pharmacists who have undergone appropriate training should be allowed to vaccinate against seasonal and pandemic influenza and to offer pneumococcal vaccine in their pharmacies.
Discontinuing Benzodiazepine Therapy: An Interdisciplinary Approach at a Geriatric Day Hospital
Authors: Chen Lori , Farrell Barbara , Ward Natalie , Russell Grant , Eisener-Parsche Pamela , Dore Naomi 
Published: December 2010

Background: Despite the known adverse effects of benzodiazepines, elderly people commonly use these drugs over long periods to treat insomnia and anxiety. This qualitative study was conducted to examine the experiences of patients and care providers in a geriatric day hospital (GDH) as patients participated in a benzodiazepine tapering process, to identify the components and processes of the benzodiazepine tapering intervention, and to begin exploring how they influence patient outcomes. Methods: The study was conducted in a GDH in a Canadian city. Data were gathered from a discussion group and from individual semistructured interviews with 13 health care providers and 5 patients. Charts were reviewed to gather demographic data and confirm provider activities. A reflexive approach was conducted whereby each care provider reviewed and modified the role description created from information provided during his or her interview. Themes were determined through constant comparative analysis of transcripts, which included 5 meetings of the research team. Results: The tapering of benzodiazepines at the GDH was effected primarily by 3 people: the physician, the pharmacist and the nurse. Other members of the interdisciplinary team were not always aware of which patients were tapering their benzodiazepine therapy, but they supported patients in a variety of ways. The patients included in this analysis were willing to taper their benzodiazepines and did not consider the experience significant in any way. Conclusion: The health care provider roles, processes and tools described here could be replicated in other environments to assist patients who are tapering benzodiazepine therapy. Further research is needed to understand the interrelationships of all components of GDH care to determine their relative importance in facilitating behaviour change related to benzodiazepine tapering.
Symptomatic Coronary Artery Disease: A Call to Action for Pharmacists
Authors: Smiley Tom 
Published: December 2010

Background: Research indicates that successful treatment of angina is associated with improved patient quality of life. This pharmacist-conducted patient survey sought to assess patients' overall satisfaction with their current angina therapies. Methods: Patients in Quebec, Alberta and Ontario taking nitrates for angina were asked if they would be willing to participate in the Symptomatic Coronary Artery Disease (SCAD) survey administered by study pharmacists. Results of the study survey were sent to the research lead and tabulated. Results: A total of 208 surveys were completed. Almost 42% of patients reported at least 1 angina episode per week. When asked to choose the category that best described the frequency of their chest pain controlled by medication, 30% of patients indicated “on occasion,” “rarely” or “never.” More than one-quarter of respondents felt that the impact of their heart condition on quality of life was significantly or extremely negative. Conclusions: Current guidelines state that the treatment goal for most patients with chronic stable angina should be complete, or near complete, elimination of the pain. Results of this survey suggest that in many instances treatment for angina-related symptoms could be optimized. Pharmacists are in an ideal position to identify and recommend therapeutic strategies for patients with symptomatic coronary artery disease.
Survey of New York Veterinarians to Assess Needs for Public Health Preparedness Training
Authors: Beckman-Moore June , Eidson Millicent , Ruland Lindsay 
Published: December 2010

ABSTRACTObjective: Because most bioterrorist disease agents are zoonotic, veterinarians are important partners in preparedness. New York State is a prime port of entry and has a network of health and emergency management agencies for response. However, knowledge and participation by veterinarians has not yet been assessed.Methods: A 25-question survey was mailed out to approximately half (1832) of the veterinarians licensed in New York State. Participants were asked about past emergency preparedness training, likelihood of participating in future training, preferred training topics, and their relationship with their local health department (LHD).Results: Completed questionnaires were received from 529 veterinarians (29%). Most (83%) reported that they were likely to participate in emergency preparedness training, but in the past 2 years, only 14% received training in zoonotic disease outbreaks and 12% in emergency preparedness. Only 21% reported having a relationship with their LHD, but 48% were interested in having one. Lack of time was the biggest obstacle to involvement with the LHD (40%). Most (69%) of those responding to the survey said they would participate in training once per year or more often.Conclusions: Inducements, such as earning continuing education credits, or the development of active networks of preparedness organizations, state and local health departments, and veterinary schools are needed to deliver emergency preparedness training and information efficiently to veterinarians.(Disaster Med Public Health Preparedness. 2010;4:300-305)
Path planning with uncertainty: A set membership approach
Authors: Ceccarelli Nicola , Di Marco Mauro , Garulli Andrea , Giannitrapani Antonio , Vicino Antonio 
Published: December 2010

AbstractThe paper addresses the path planning problem in a set theoretic framework. The considered scenario is that of a mobile robot exploiting range and bearing measurements with respect to known landmarks to localize itself. By assuming unknown‐but‐bounded measurement noise, set membership localization techniques are used to estimate the uncertainty of each robot pose within the considered environment. The path planning problem is formulated and solved, with the aim of minimizing the total uncertainty associated with the travelled path. Practical issues such as limited sensory range and obstacle avoidance are taken into account. The proposed technique is validated via numerical simulations. Copyright © 2010 John Wiley & Sons, Ltd.