bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative chromatographic adsorbabilities of some azines, thioles and thienopyridines, their heteroatom oxides and other derivatives on silica gel
Authors: Klemm L. H. , Lee F. H. W. , Lawrence Ross F. 
Published: April 2009

AbstractThin layer chromatographic Rf data on silica gel are reported for 64 compounds containing either a thiole sulfur atom, one or more azine nitrogen atoms, or both. Thiole adsorbates are compared with 28 aromatic hydrocarbons and non‐heterocyclic sulfur compounds. In general the orders of Rf values found are thioles > sulfides > sulfones > sulfoxides > azine N‐oxides and azines > azine‐N‐oxides. Results are interpreted in terms of hydrogen bonding from the silica gel to the adsorbate. The different orders of adsorbability found amongst four series of condensed thiophenes and their arene analogs for chromatography on silica gel and on alumina are rationalized in terms of planarity and acid‐base interactions. Correlations of the tlc data with separations on columns are presented.
Synthesis of a novel 8‐thia‐1,4‐diazacycl[3.3.2] azine
Authors: Campaigne E. , Selby T. P. 
Published: April 2009

AbstractA unique covalently hydrated cyclazine adduct, 2‐imino‐6a‐hydroxy‐4,5,6,6a‐tetrahydro‐7H‐8‐thia‐J, 4‐diazacycl[3.3.2]azin‐5‐one hydrochloride was prepared by reacting ethyl 4‐chloro‐acetoacetate with 4,6‐diamino‐2‐thiopyrimidine in neutral alcohol. Neutralization gave 2‐imino‐5,6a‐dihydroxy‐6,6a‐dihydro‐7H‐8‐thia‐1,4‐diazacycl[3.3.2]azine which decomposed to 4,6‐diamino‐2‐acetonylthiopyrimidine upon heating in water. Warming the hydrated hydrochloride in concentrated hydrochloric acid caused dehydration to yield 2‐imino‐5‐hydroxy‐6H‐8‐thia‐1,4‐diazacycl[3.3.2]azine hydrochloride. Partial isomerization (20%) to 2‐imino‐5‐hydroxy‐7H‐8‐thia‐1,4‐diazacycl[3.3.2]azine hydrochloride occurred during recrystallization from aqueous acidic methanol. The free base, 2‐imino‐5‐hydroxy‐7H‐8‐thia‐1,4‐diazacycl[3.3.2]azine was obtained after neutralizing either of the tautomeric hydrochlorides. Treating the free base with trifluoroacetic acid produced a mixture of the trifluoroacetate salts of the two tautomeric bases. Isomerization of one trifluoroacetate salt into the other in trifluoroacetic acid was observed by pmr at room temperature. Both 2‐amino‐5‐hydroxy‐7‐nitroso‐8‐thia‐1,4‐diazacycl[3.3.2]azine and 2‐amino‐5‐hydroxy‐6‐nitroso‐8‐thia‐1,4‐diazacycl[3.3.2]azine were isolated after nitrosation of the hydrochloride mixture.
Antimykotische wirkstoffe. VIII. Aufbau von dehydro‐N‐mannich‐basen durch piperidin‐ und piperazinring
Authors: Kreutzberger Alfred , Kreutzberger Elfriede 
Published: April 2009

AbstractAus einer die Umsetzung von Cyanamid (1) und s‐Triazin (2) mit einem sekundàren Amin (5) beinhaltenden Dreikomponcntenreaktion gehen die Dehydro‐N‐Mannich‐Basen (6), unter denen 6a, b und c antimykotische Wirksamkeit aufweisen, hervor.
Reaction of sulfene with heterocyclic N,N‐disubstituted α‐aminomethvlene ketones V. Synthesis of 1,2‐oxatliiino[5.6‐c] pyridine and 1,2‐oxathiino[5,6‐c] quinoline derivatives
Authors: Mosti Luisa , Menozzi Giulia , Schenone Pietro 
Published: April 2009

AbstractReaction of sulfene with N,N‐disubstituted 3‐aminomethylene‐1‐(methyl, methylphenyl, phenyl)‐4‐piprridones and 3‐aminomethylene‐2,3‐dihydro‐1‐plumy 1–4(1H) quinolones gave N,N‐disubstituted 4‐amino‐3,4,5,6,7.8‐hexahydro‐6‐(methyl, methylphenyl, phenyl)‐1,2‐oxathiino‐[5,6‐c] pyridine 2,2‐dioxides and 4‐amino‐6‐phenyl‐3,4,5,6‐tetrahydro‐1,2‐oxathiino[5,6‐c]quinoline 2,2‐dioxides, respectively, whereas N,N‐disubstituted 3‐aminomethylene‐2,3‐dihydro‐1‐methyl‐4(1H) quinolones did not react. Slow air oxidation in the cold of intermediates 2,3‐dihydro‐3‐hydroymethyIene‐1‐(methyl, phenyl)‐4(1H) quinolones gave the corresponding 1‐substituted 1,4‐dihydro‐4‐oxo‐3‐quinolinecarboxyaldehydes.
The synthesis of some benzo[d1]furo[3,2‐e] [1,4] diazepin‐2‐ones
Authors: Ashby John , Ramage E. M. 
Published: April 2009

AbstractReaction of 3‐amino‐2‐benzoylbenzo[b]furan with bromoacetyl bromide followed by cyclization in methanolic ammonia gave 5‐phenyl‐1,3‐dihydrobenzo[d′] furo[3,2‐e] [1,4]diazepin‐2‐one, a representative of a new ring‐system. The corresponding chloro substituted diazepin‐2‐one was similarly prepared from 3‐amino‐2‐(4‐chlorobenzoyl) benzo[b] furan. Some alkylation and thionation reactions of these diazepines have been investigated.
Structural reassignment of the alleged 6‐hydroxy‐1,2,4‐triazine‐3,5‐(2H,4H)dione
Authors: Schuan Thomas J. , Sanford Timothy J. , White It. L. , Miles Nelson J. 
Published: April 2009

AbstractThe reaction of 6‐amino‐1,2,4‐triazine‐3,5‐(2H,4H)clione with sodium hydroxide or nitrous acid has been shown to give 5‐hydroxy‐1,2,4‐triazole‐3‐carboxylic acid instead of 6‐hydroxy‐1,2,4‐triazine‐3,5‐(2H,4H)dione as reported in the literature. The triazolecarboxylic acid was also obtained from the aminotriazine and hydrochloric acid.
Addition des azidosulfatcs d'arylr sur le norborncne
Authors: Hedayatullah Mir , Guy Alain 
Published: April 2009

AbstractLa cycloaddition des azidosulfatcs d'aryle sur le norhornène dans l'acétonitrile à 25°, conduit, après perte d'azote, à des aziridines N‐substituées par des restes aryloxysulfonyles. Par rmn et svnthèse indépendante on montre que l'addition est stére'ospécifique avec formation exclusive d'aziridines exo.
Synthesis of I‐Hydroxy‐2,4‐diphenylpyrrolo[2,3‐d] pyridazin‐7(6H)one
Authors: Migliara Onofrio , Petruso Salvatore 
Published: April 2009

AbstractThe synthesis of 1‐hydroxy‐2,4‐diphenylpyrrolo[2,3‐d]pyridazin‐7(6H)one is described.
Cyclic imides. XII(i). Absorption and fluorescence spectra of 3‐benzamidophthalimides
Authors: Caswell Lyman R. , Campbell Jo‐Anne B. , Cecil Rosemary 
Published: April 2009

AbstractThe ultraviolet absorption, fluorescence, and infrared absorption spectra of fifteen 3‐benz‐amidophthalimides are described. In general, the nature or position of the substituents on the benzamide moiety has little effect on the ultraviolet absorption and fluorescence spectra of these, compounds. The absorption baud at 271 nm is more sensitive to substituent variations than the other two bands (at 227 nm and 341 nm), indicating this band is a composite of bands observed in the spectra of 3‐aminophthalimide and the substituted benzamide. The fluorescence of 3‐amino‐phthalirnide and the 3‐benzamidophthalimides is due to the same transitions. The infrared absorption wavenumbers for the amide and imide vibrations of the 3‐benzamidophthalimides are characterized.
Benzo[B]thiophene derivatives XXIV. Oxidation of o‐dihydroxybenzo[b]thiophene methyl ethers
Authors: Campaigne K. , Homfeld E. 
Published: April 2009

AbstractThe attempted oxidative demethylation of a series of o‐dihydroxybenzo[b]thiophene methyl ethers with cerium (IV), argentic oxide, periodale and thallate usually led to intractable mixtures. However, in one ease, use of ceric ammonium nitrate resulted in nitration of the benzo[b]‐thiophene ring. In another example, treatment with aqueous periodate or thallate resulted in oxidative hydroxylation of benzo[b]thiophene.
Synthesis of 5,6‐dihydro‐4H‐pyrrolo[1, 2‐a] [1,4]benzodiazepines
Authors: Cheeseman G. W. H. , Greenberg S. G. 
Published: April 2009

AbstractThe title compounds are. Prepared by the reaction of carbonyl compounds with 1‐(2′‐amino‐methylphenyl)pyrrole hydrochloride.
Condensed Pyridazines. Part I. Synthesis of 2‐Oxo‐2H‐pyrano[2,3‐D]‐pyridazine and 2‐Oxo‐2H‐pyrano[2,3‐c] pyridazine
Authors: Maeba Isamu , Ando Masahiko , Yoshina Shigetaka , Castle Raymond N. 
Published: April 2009

AbstractThe reaction of 4,7‐diehlorofuro[2,3‐d]pyridazine (1) with potassium cyanide in DMSO gave two products, (E)‐3,6‐diehloro‐5‐(2‐cyanovinyl)‐4‐hydroxypyridazine (II) and 5,8‐dichloro‐2‐oxo‐2H‐pyrano[2,3‐d]pyridazine (III) as a result of ring opening or ring expansion. A new ring system, 2‐oxo‐2H‐pyrano[2,3‐c]pyridazines (IX, XII, XIII) was obtained from 5,8‐dichloro‐3‐methyl‐2‐oxo‐2H‐pyrano[2,3‐d]pyridazine (VI).
Condensed pyridazines. Part II. Synthesis of pyrido[2,3‐C] pyridazines
Authors: Maeba Isamu , Castle Raymond N. 
Published: April 2009

AbstractThe synthesis of some pyrido[2,3‐c]pyridazines from 5,8‐diehloro‐3‐methyl‐2‐oxo‐2H‐pyrano‐[2,3‐d]pyridazine (I) is described. Attempted oxidation of 8‐amino‐3‐chloro‐1,6‐dimethyl‐4,7‐dioxo‐1,4,7,8‐tetrahydropyrido[2,3‐c]pyridazine (VI) with LTA led only to the deaminated compound VII. Treatment of VI with LTA A in the presence of cyclohexene gave the nitrene adduct XI.
On the photooxygenation and autoxidation of dipyrrylmethenes and dipyrrylmethanes
Authors: Norris R. D. , Lightner D. A. 
Published: April 2009

AbstractThe dye‐sensitized photooxygenations of 4,4′‐diethyl‐3,5,3′5′‐tetramethyldipyrrylmethene and 4,4 ‐diethyl‐3,5,3′5‐tetramethyldipyrrylmethane have been investigated in neutral, basic and acidic methanol solution. Several photoproducts are common to the photooxygenation of both substrates. The dipyrrylmethene was detected as an intermediate in the photooxygenation of the dipyrrylmethane; however, it was determined not to be an important precursor to monopyrrole products. Autoxidations of the two dipyrrole compounds were also investigated and were found to be slower than the corresponding photooxygenation. Autoxidation and photooxygenation were both found to be faster in basic than in acidic methanol with the dipyrrylmethane faster than with the dipyrrylmethene in the same solvent.
Synthesis of heterocyclic compounds. XIII. 2‐amino‐3‐benzyl‐3,5‐dieyano‐6‐methoxy‐4‐phenyl‐3,4‐dihydropyridines
Authors: Fuentes L. , Lorente A. , Soto J. L. 
Published: April 2009

AbstractA synthesis of 2‐amino‐3‐benzyl‐3,5‐dicyano‐6‐methoxy‐4‐phenyl‐3,4‐dihydropyridines from benzylmalononitriles and benzylidenemalononitrile is described. The structures of the new compounds have been elucidated on the basis of spectral data (ir, nmr, ms), and in two cases (Vb and Ve) by chemical degradation.
Heterocyclic. Compounds. X. Bis(2‐chloroethyl)amino substituted β‐lactams as potential antineoplastic agents
Authors: Manilas M. S. , Min S. G. A. , Glazer R. D. 
Published: April 2009

AbstractThe synthesis of variously substituted β‐lactams carrying a bis(2‐chloroethyl) amino group is described. Some of these compounds show mild antitumor activity and low toxicity.
Reactions of nitrogen compounds with ruthenium tetroxide. Determination of the absolute configuration of 3‐ethylpiperidine
Authors: Morlacchi Flaviano , Losacco Vincenzo , Tortorella Vincenzo 
Published: April 2009

Abstract(‐)‐3‐Kthylpiperidine and (R)‐(‐)‐2‐ethylglutarie acid have been chemically correlated through N‐subslituted α‐ethylglutarimides obtained from the oxidation of optically active N‐ethyl‐ and N‐benzyl‐3‐ethylpiperidine with ruthenium tetroxide. The (R)‐(‐) configuration of (‐)‐3‐ethylpiperidine was confirmed by CD measurements. The selective oxidation of endocyclic methylenes linked to the nitrogen atom was explained in term of different conformational freedom of endo‐ and exocyclic methylene groups.
On the mechanism of the conversion of 6‐chloropyrido[2,3‐B]pyrazine into 1h‐lmidazo[4,5‐b] pyridine by potassium amide in liquid ammonia
Authors: Nagel A. , Van Der Plas H. C. , Geurtsen G. , Van Der Kuilen A. 
Published: April 2009

AbstractThe synthesis of a number of 2‐R1, 3‐R2‐6‐X‐pyrido[2,3‐b]pyrazines (1) is reported and their reaction with potassium amide in liquid ammonia investigated. Ring contraction into a 2‐R‐1H‐imidazo[4,5‐b]pyridine was found to occur with X = Cl, R1 = H, R2 = C6H5 (1b); X = Cl, R1 = R2 = C6H5 (1c); X = Cl, R1 = H, R2 = t‐C4H9 (1d). Besides ring contraction, an increasing amount of dechlorination of 1 was found: 1a, 20%; 1b, 30%; 1d, 40%; 1c, 60%; 1g, 95%. 1e (X = Cl, R1 = t‐C4H9, R2 = H) yields the unreactive anionic σ‐adduct at C‐3 i.e., 3‐amino‐2‐t‐butyl‐6‐chloro‐3,4‐dihydropyrido[2,3‐b]pyrazine. The ring contraction only proceeds with X = Cl. 1b (X = F) gives an amino‐defluorination, 1b (X = Br) exclusively undergoes reductive debromination. The ring contraction of 1a (X = Cl, R1 = R2 = H) is investigated by 15N‐ and 13C‐labelling. It is concluded that the conversion into 1H‐imidazo[4,5‐b]pyridine proceeds via the reactive anionic σ‐adduct at C‐2, under exclusive elimination of C‐2.
Competition entre les réactivités dipolarophiles et nucléophiles des pyrazolines‐2 dans l'action de l'oxyde de benzonitrile. Synthèse, identification, comportement chimique des tétrahydropyrazolo‐[4,5‐b] oxadiazoles‐1,2,4
Authors: Giberl J.‐P. , Petrus C. , Petrus F. 
Published: April 2009

AbstractL'action de l'oxyde de benzonitrile sur une série de pyrazolines‐2 permet de montrer la réaetivité dipolarophile de la liaison C=N et la présence de deux sites nucléophiles; l'azote en 1, ou le carbone en 3 pour les pyrazolines‐2 non substituées en 1 ou 3. La régiospécificité de la cycloaddition est démontrée. Cette dernière conduit à une nouvelle série d'hétérocycles condenses que nous décrivons.
Synthesis of heterocyclic analogs of α‐methyldopa
Authors: Tilley Jefferson W. , Levitan Paul , Kierstead Richard W. 
Published: April 2009

AbstractThe condensation of various halomethyl heterocycles with the potassium salt of the alanine derivative 3, followed by hydrolysis, gave a series of novel 3‐heterocyclic‐2‐methylalanines.
2‐(Aminomethyl)phthalimide. A new reagent for the synthesis of 2,4‐benzodiazepines
Authors: Lauer Rudolph F. , Zenchoff Gladys 
Published: April 2009

Abstract2,4‐Benzodiazepines can be prepared by condensation of an activated 2‐benzoylbenzoic acid with 2‐(aminomelhyl)phthalimide. A synthesis of this reagent is described.
4‐Thiazolidinones and 2,4‐thiazolidinediones from α‐mercaptopropionic acid and carbodiimides
Authors: Monforte P. , Fenech G. , Basile M. , Ficarra P. , Silvestro A. 
Published: April 2009

Abstract2,3‐Substituted 5‐methyl‐4‐thiazolidinones (1) and 3‐substituted 5‐methyl‐2,4‐thiazolidine‐diones (II) were prepared by reacting some carbodiimides with α‐mercaptopropionic acid, with the purpose of obtaining potentially chemotherapeutic agents. It is noteworthy that 3‐cyclohexyl‐5‐methyl‐2,4‐thiazolidinedione (IId) was obtained in three different crystalline structures. Some secondary compounds were also obtained: the N,N‐disubstituted ureas (III) and thioureas (IV) in all cases, the dianilides (V) and the tri‐substituted guanidines (VI) from the arylcarbodiimides, and the dithiolactide (VII) from the isopropyl‐ and cyclohexylcarbodiimides.
Reaction of 1‐formyladamantane with heterocyclic compounds. Mass spectra, antibacterial and antifungal activity
Authors: Fenech G. , Monforte P. , Chimirri A. , Grasso S. 
Published: April 2009

Abstract1‐Formyladamantane reacts with some amino derivatives to give I, II, III and IV. 3‐Substiluted 2‐adamantyl‐4‐thiazolidinones (V), (VI) and (VII) were obtained by reacting the above compounds with mercaptoacetic acid. Their structure was established by ir, pmr and mass spectroscopy. All compounds synthesized inhibit the growth of gram‐negative and gram‐positive bacteria and fungi.
arabinonucleosides
Authors: Montgomery John A. , Jeanette Thomas H. 
Published: April 2009

AbstractThe α‐D‐arabinonucleosides of cytosine (6) and 5‐fluorouracil (9) were prepared from the 2,3,‐5‐tri‐O‐benzoyl‐D‐arabinofuranosyl halides, in keeping with thetransrule. The 2′‐O‐methyl‐)3‐D‐arabinonucleosides of 5‐fluorouraeil (β‐14) and adenine (β‐21a) were prepared from 3,5‐di‐O‐(4‐ehlorobenzoyl)‐2‐O‐methyl‐α‐D‐arabinofuranosyl chloride, although in both cases a lesser amount of the α‐anomer was also found. Reaction of 3,5‐di‐O‐(4‐chlorobenzoyl)‐2‐deoxy‐2‐(methylthio)‐α‐D‐arabinofuranosyl chloride, prepared in four steps from methyl 2,3‐anhydro‐α‐D‐ribofurano‐side (15), withN‐benzoyladenine gave slightly more of the β‐ than the α‐arabinonucleoside20b. The β‐anomer was converted to 9‐[2‐deoxy‐2‐(methylthio)‐β‐D‐arabinofuranosyl]adenine. Only 1‐α‐D‐arabinofuranosylcytosine (6) proved to be cytotoxic.
Mononuclear heterocyclic rearrangements. Part III. Rearrangement of the P‐methoxyphenylhydrazone and the m‐nitrophenylhydrazone of 3‐benzoyl‐5‐phenyl‐1,2,4‐oxadiazole in dioxane/water in the pS+ range 3.8–11.5
Authors: Spinelli Domenico , Corrao Antonino , Frenna Vincenzo , Vivona Nicolò , Ruccia Michele 
Published: April 2009

AbstractThe rates of the mononuclear heterocyclic rearrangement of the p‐methoxyphenylhydrazone (Ib) and the m‐nitrophenylhydrazone (1c) of 3‐benzoyl‐5‐phenyl‐1,2,4‐oxadiazole have been measured in the range of pS+ 3.8–11.5 (solvent: dioxane/water 1:1, v:v) and compared with those of the unsubstituted phenylhydrazone (Ia). The obtained results show that in the base‐catalyzed range, electron‐repelling as well as electron‐withdrawing substituents accelerate the rearrangement rates.
Synthesis of chromones
Authors: Reynolds G. A. , Van Allan J. A. , Seidel A. K. 
Published: April 2009

AbstractA general procedure for the preparation of chromones from the boron difluoride complex of o‐hydroxyaryl methyl ketones is described. One of the best methods used for the preparation of chromones and benzochromones is the treatment of o‐hydroxyaryl methyl ketones with the dimethylacetal of dimethylformamide followed by treatment with sulfuric acid (1). We previously had shown (2) that benzochromone 4 was prepared in reasonable yield by the following reaction sequence.
Azobilirubin and azomesobilirubin isomers. A carbon‐13 nmr analysis
Authors: Salmón Manuel , Legoff I. , Joseph‐Nathan P. 
Published: April 2009

AbstractThe 13C nmr chemical shifts of azobilirubin and azomesobilirubin isomers are reported. The signals are assigned on the basis of substituent effects and comparison with structurally related compounds.
A reinvestigation of the bamberger‐ham phenazine. Synthesis: A limitation
Authors: Sawhney Shanti N. , Boykin David W. 
Published: April 2009

AbstractThe Bamberger‐Ham condensation of 4‐substituted nitrosobenzenes in concentrated sulfuric acid reported as a method of synthesis for phenazine N‐oxides has been found to be limited to electron donating substituents. Methyl 4‐nitrosobenzoale has been found to react under these conditions to give dimethyl 2‐nitrodiphenylamine‐4, 5‐diearboxylate (2). Compounds of unknown structure previously reported to arise from acid treatment of 4‐bromo‐ and 4‐chloronilrosobenzene have been shown to be 4, 5‐dibromo‐2‐nitrosophenylamine (10) and the analogous dichloro compound. Treatment under stronger acidic conditions (oleum) converted 10 but not 2 into the corresponding phenazine N‐oxide. Mechanistic implications are discussed.
Some reactions of 1,2‐dihydropyridines with cyanogen azide. Synthesis of üiazabieyclo[4.1.0]hept‐4‐enes
Authors: Ondrus T. A. , Knaus E. E. , Ciam C. S. 
Published: April 2009

AbstractThe regiospecific 1,3‐dipolarcycloaddition reaction of 1,2‐dihydropyridines 1 with cyanogen azide 2 afford 2,7‐diazabieyelo[4.1.0]hept‐4‐enes 3 in quantitative yield. Catalytic hydrogenation of 3 gives rise to a tautomeric mixture of piperidylidene‐2‐cyanamides 5 in quantitative yield. Alternatively treatment of 3 with a suspension of alumina oxide in chloroform yields 1,2,5,6‐tetrahydropyridylidenes 4 which are also quantitatively reduced to 5.
Electrochemical behaviour of heterocyclic amidines I. Anodic oxidation of 2‐amino‐5‐ethoxycarbonyl‐4‐methylthiazole
Authors: Cauquis G. , Pierre G. , Elnagdi M. H. , Fahmy H. M. 
Published: April 2009

AbstractThe behaviour of 2‐amino‐5‐ethoxycrbonyl‐4‐methylthiazole on oxidation at a rotating platinum disc electrode is reported. The mechanism of the formation of the azo and hydraazo dimeric compounds as main oxidation products is discussed.
Substituent effects in chemical carcinogenesis: Methyl derivatives of the benzacridines
Authors: Smith Idea A. , Seybold Paul G. 
Published: April 2009

AbstractAn explanation for the different carcinogenic potencies observed among methyl derivatives of the angular benzacridines is given in terms of the tendencies of these compounds to undergo specific metabolic activating reactions analogous to those of polycyclic aromatic hydrocarbons. Theoretical reactivity indices representing these reactions correlate with the carcinogenic activities of these compounds.
Synthèse et réactivité de dihydrotriazines et de dihydrotriazolotriazines
Authors: Daunis Jacques , Djouai‐Hifdi Laila , Lopez Hélène 
Published: April 2009

AbstractLes dihydro‐4,5 triazinones‐3 peuvent ětre préparées de façon générale par hydrolyse basique des methylmereapto‐3 dihydro‐4,5 triazines; parmi toutesles méthodes de méthylation envisagées, action du diazométhane, du sulfate ou de l'iodure de méthyle en présence de méthylate de sodium ou de carbonate d'argent, ou du bromure de méthyle en catalyse par transfert de phase, seule cette derniére conduit aux différents produitsN‐méthylés en position 2 ou (et) 4. L'action de l'acide formique sur l'hydrazino‐3 triméthyl‐5,5,6 dihydro‐2,5 triazine donne un mélange de dihydrotriazolotriazines résultant des deux possibilités de cyclisation. Deux types de synthèse univoque de dihydro triazolo[4,3‐b] triazines sont décrits.
The synthesis of 8‐oxoberbines containing a heterocyclic D‐ring by enamide photocyclizations
Authors: Lenz George R. 
Published: April 2009

AbstractThe photocyclization of 2‐heteroyl‐1‐methyleneyl‐3,4‐dihydro‐6,7‐dimethoxyisoquinolines, where heteroyl = benzofuran, benzo[b]thiophene, coumarin and nicotinoyl, leads to the corresponding 8‐oxoberbines containing a heterocyclic D‐ring. Dehydrogenation can accompany photocyclization depending on the reaction conditions employed, or alternatively DDQ can be used to effect this dehydrogenation.
Hétérocyclisations intramoléculaires par reaction d'oxymereuration V. Oxymercuration intramoléculaire d'alcools γ‐éthyléniques. Synthèse d'alcools spiranniques
Authors: Spéziale Vincent , Lattes Armand 
Published: April 2009

AbstractL'hétérocyclisation intramoléculaire, par l'acétate mercurique, d'alcools γ‐éthyléniques dont la double liaison est intracyclique et le groupement hydroxy le en γ du cycle, conduit à des éther‐oxydes spiranniques. L'action du borohydrure de sodium sur les chloromercuriques en solution dans du N,N‐diméthylformamide saturé par de l'oxygène, permet d'obtenir les alcools spiranniques correspondants avec de bons rendements.
Dinitrofuran derivatives
Authors: Sitzmann Michael E. 
Published: April 2009

AbstractThe synthesis and properties of twelve 2‐substituted 3,5‐dinitrofurans are described. These derivatives include bromo‐, iodo‐, azido‐, hydroxy‐, amino‐, 3,5‐dinitro‐2‐furanyl‐, 5‐nitro‐2‐furanyl‐, acetamido‐, and carbamate compounds.
Studies on furan derivatives IV. A simple preparation of α‐substituted β‐(5‐nitro‐2‐furyl)ethynyls from α‐substituted β‐(5‐nitro‐2‐furyl)vinylamines
Authors: Tanaka Akira , Usui Toshinao , Yoshina Shigetaka 
Published: April 2009

Abstractα‐Substituted β‐(5‐nitro‐2‐furyl)ethynyls were conveniently prepared by the deamination of α‐substituted β‐(5‐nitro‐2‐furyl)vinylamines. Also the application of this reaction towardα,β‐bis(p‐nitrophenyl)vinylamine was examined and affordedα,β‐bis(p‐nitrophenyl)ethynyl as the main product.
Tetronic acids and derivatives. Part V. Synthesis of 5‐hydroxy‐1H‐pyrazoles via 4‐hydrazino‐5H‐furan‐2‐ones. Reaction of hydrazines on tetronic acids
Authors: Gelin Suzanne , Pollet Patrick 
Published: April 2009

AbstractThe conversion of tetronic acids 1 to 3(1‐hydroxy alkyl)‐5‐hydroxy‐1H‐pyrazole derivatives 3, 5, 7 and 12 is described. The formation is shown to proceed via base‐catalyzed rearrangement of the intermediate 4‐hydrazino‐5H‐furan‐2‐one derivatives.
Synthesis in the diazasteroid group VIII. Synthetic studies of the 14,17‐diazasteroid system
Authors: Yamazaki Takao , Matoba Katsuhide , Imai Toshio , Castle Raymond N. 
Published: April 2009

AbstractTwo synthetic routes leading to the 14,17‐diazasteroid system have been developed. One of these gives 14,17‐diazagona‐1,3,5(10),6,8,9,11,13(17)heptaene (V), prepared from benzo[f]quinolin‐3(4H)one (I) and ethanolamine. The other route gives 14,17‐diazagona‐1,3,5(10),8,12‐heptaen‐11‐one (XVIa) via the reaction of 2‐tetralone with ethyl 2‐imidazolidinylidenacetate (IXa).