bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Cross‐Metathesis of Allyl Halides with Olefins Bearing an α‐Alkoxy Amide Group.
Authors: Yun Jeong In , Kim Deukjoon , Lee Jongkook 
Published: June 2011

AbstractThe process is most efficient with amide substrates bearing a Weinreb segment and Hoveyda—Grubbs catalyst.
ChemInform Abstract: Introducing a Podand Motif to Alkyne Metathesis Catalyst Design: A Highly Active Multidentate Molybdenum(VI) Catalyst that Resists Alkyne Polymerization.
Authors: Jyothish Kuthanapillil , Zhang Wei 
Published: June 2011

AbstractThe catalyst prepared in situ from the Mo(VI) propylidyne complex MOL and podand amine AMI exhibits high activity in the metathesis reaction of a variety of alkynes.
ChemInform Abstract: Enantioselective Iridium‐Catalyzed Vinylogous Reformatsky‐Aldol Reaction from the Alcohol Oxidation Level: Linear Regioselectivity by Way of Carbon‐Bound Enolates.
Authors: Hassan Abbas , Zbieg Jason R. , Krische Michael J. 
Published: June 2011

AbstractGood to excellent levels of regioselectivity and uniformly high levels of enantioselectivity are achieved for the hydroxycarboxylic esters obtained by the reaction of a range of alcohols or aldehydes with crotonate (I) in the presence of iridium complex IRI.
ChemInform Abstract: Synthesis and Innate Immunosuppressive Effect of 1,2‐Cyclopentanediol Derivatives.
Authors: Kikuchi Haruhisa , Okazaki Kaori , Sekiya Mizuki , Uryu Yasuyuki , Ueda Kazunori , Katou Yasuhiro , Kurata Shoichiro , Oshima Yoshiteru 
Published: June 2011

Abstract1,2‐Cyclopentanediol derivative (VIII) and a series of structurally related compounds, e.g. (IX), are synthesized and evaluated for their immunosuppressive activity.
ChemInform Abstract: Kinetic Resolution of the Racemic 1‐(Aryloxyzol‐2‐yl)carbinols with Achiral Carboxylic Acids by Asymmetric Esterification: A New Method for the Preparation of Chiral 1,2‐Amino Alcohols.
Authors: Nakata Kenya , Ono Keisuke , Shiina Isamu 
Published: June 2011

AbstractThe kinetic resolution of racemic alcohols (I) with phenylpropanoic acid (II) is examined and the optimized structure of the oxazole part in substrates (I) is determined.
ChemInform Abstract: SN2′ Addition/1,2‐Elimination of Dimethylsulfonium Methylide with Epoxy Vinyl Sulfones: Synthesis of Exocyclic Cross‐Conjugated Dienyl Sulfones.
Authors: Sikervar Vikas , Fuchs Philip L. 
Published: June 2011

AbstractThe title reaction affords enantiopure six and seven membered cross‐conjugated hydroxy vinyl sulfones (III), (V), and (VII) in moderate to good yields.
ChemInform Abstract: Highly Efficient Asymmetric Vinylogous Mannich Reaction Induced by O‐Pivaloylated D‐Galactosylamine as the Chiral Auxiliary.
Authors: Yu Jipan , Miao Zhiwei , Chen Ruyu 
Published: June 2011

AbstractA new and efficient asymmetric access to a number of γ‐butenolide derivatives is presented.
ChemInform Abstract: Catalytic Asymmetric 1,3‐Dipolar Cycloaddition of N‐Unprotected 2‐Oxoindolin‐3‐ylidene Derivatives and Azomethine Ylides for the Construction of Spirooxindole‐Pyrrolidines.
Authors: Liu Tang‐Lin , Xue Zhi‐Yong , Tao Hai‐Yan , Wang Chun‐Jiang 
Published: June 2011

AbstractA simple, efficient, and stereoselective method to prepare biologically important spirooxindole‐pyrrolidines like (III) is reported.
ChemInform Abstract: General Synthesis of Mono‐, Di‐, and Triacetylated Indoles from Indolin‐2‐ones.
Authors: Jha Mukund , Chou Ting‐Yi , Blunt Brian 
Published: June 2011

AbstractThe combination of a DMAP‐catalyzed acetylation of indolinones of type (I) with an enzyme‐assisted deacetylation reaction results in the chemoselective formation of 1,3‐diacetyl‐2‐hydroxyindoles (IV).
ChemInform Abstract: Rhodium(II) Acetate‐Catalyzed Stereoselective Synthesis, SAR and anti‐HIV Activity of Novel Oxindoles Bearing Cyclopropane Ring.
Authors: Kumari Garima , Nutan Nutan , Modi Manoj , Gupta Satish K. , Singh Ramendra K. 
Published: June 2011

AbstractStereoselective cyclopropanation of diazolactams (I) leads to novel oxindoles whose structure is based upon docking studies.
ChemInform Abstract: 12‐Tungstosilicic Acid Supported on Different Carriers: Pronounced Catalytic Activity in the Synthesis of Bis(indolyl)methanes under Solvent‐Free Conditions.
Authors: Rafiee Ezzat , Zolfagharifar Zohre , Joshaghani Mohammad , Eavani Sara 
Published: June 2011

Abstract12‐Tungstosilicic acid supported on different carriers are used as catalysts for the synthesis of bis(indolyl)methanes from indole and carbonyl compounds.
ChemInform Abstract: (E)‐9‐(2‐Iodovinyl)‐9H‐carbazole: A New Coupling Reagent for the Synthesis of π‐Conjugated Carbazoles.
Authors: Pawluc Piotr , Franczyk Adrian , Walkowiak Jedrzej , Hreczycho Grzegorz , Kubicki Maciej , Marciniec Bogdan 
Published: June 2011

AbstractStereoselective silylative coupling of N‐vinylcarbazole (I) followed by iododesilylation allows an easy access to the desired versatile building block (III).
ChemInform Abstract: Catalytic Asymmetric Syntheses of Isoxazoline‐N‐oxides under Phase‐Transfer Conditions.
Authors: Kano Taichi , Yamamoto Akihiro , Song Sunhwa , Maruoka Keiji 
Published: June 2011

AbstractThe conjugate addition/ O‐alkylation sequence under application of a chiral phase transfer catalyst proceeds with moderate to good enantioinduction.
ChemInform Abstract: A Facile and Eco‐Friendly Synthesis of Diarylthiazoles and Diarylimidazoles in Water.
Authors: Kumar Dalip , Kumar N. Maruthi , Patel Gautam , Gupta Sudeep , Varma Rajender S. 
Published: June 2011

AbstractA simple procedure is presented for the reaction of α‐tosyloxy ketones with thioamides or amidines.
ChemInform Abstract: Novel, Mild, and Highly Efficient Method for the Synthesis of 2‐Arylbenzothiazoles by the Oxidation of 2‐Arylbenzothiazolines with Silicon Lewis Acids.
Authors: Sonika Sonika , Meenakshi Meenakshi , Malhotra Rajesh 
Published: June 2011

AbstractBenzothiazoles (II) and (IV) are synthesized by oxidation of corresponding benzothiazolines using TmsCl or dimethyldichlorosilane.
ChemInform Abstract: A Fully Automated, Multistep Flow Synthesis of 5‐Amino‐4‐cyano‐1,2,3‐triazoles.
Authors: Smith Catherine J. , Nikbin Nikzad , Ley Steven V. , Lange Heiko , Baxendale Ian R. 
Published: June 2011

AbstractIt allows an efficient, safe, and clean access to a number of biologically interesting title triazoles.
ChemInform Abstract: Molecular Iodine‐Catalyzed, One‐Pot, Diastereoselective Synthesis of 4‐Amido Tetrahydropyrans.
Authors: Sabitha Gowravaram , Bhikshapathi M. , Nayak Sambit , Yadav J. S. 
Published: June 2011

AbstractTitle compounds (IV) and (VI) are synthesized via a Sakurai—Prins—Ritter reaction sequence with high diastereoselectivity.
ChemInform Abstract: Synthesis, Human Monoamine Oxidase Inhibitory Activity and Molecular Docking Studies of 3‐Heteroarylcoumarin Derivatives.
Authors: Delogu Giovanna , Picciau Carmen , Ferino Giulio , Quezada Elias , Podda Gianni , Uriarte Eugenio , Vina Dolores 
Published: June 2011

AbstractNovel 3‐heteroarylcoumarin derivatives (III) are synthesized via classical Perkin reaction.
ChemInform Abstract: Sodium [2′‐[(Cyclopropanecarbonyl‐ethyl‐amino)‐methyl] ‐4′‐(6‐ethoxy‐pyridin‐3‐yl)‐6‐methoxy‐biphenyl‐3‐yl]‐acetate (AM432): A Potent, Selective Prostaglandin D2 Receptor Antagonist.
Authors: Stock Nicholas , et al. et al. 
Published: June 2011

AbstractStructure—activity‐relationship studies of recently discovered biphenyl acetic acid based DP2 antagonists culminate in the identification of the title compound (I) as a potential candidate for clinical development.
ChemInform Abstract: Synthesis of Tetrahydro‐5‐azaindoles and 5‐Azaindoles Using Pictet—Spengler Reaction — Appreciable Difference in Products Using Different Acid Catalysts.
Authors: Shumaila Abdullah M. A. , Puranik Vedavati G. , Kusurkar Radhika S. 
Published: June 2011

AbstractDisubstituted tetrahydroazaindoles (III) are obtained as trans‐isomers using glacial acetic acid during the title reaction.
ChemInform Abstract: Synthesis and Anticancer Activities of Some Novel 2‐(Benzo[d]thiazol‐2‐yl)‐8‐substituted‐2H‐pyrazolo [4,3‐c]quinolin‐3(5H)‐ones.
Authors: Vasconcelos Thatyana R. A. , et al. et al. 
Published: June 2011

AbstractTitle compounds (III) are evaluated for their in vitro antiproliferative activities against four human cancer cell lines (MDA‐MB‐435, HL‐60, HCT‐8, and SF‐295) using doxorubicin as positive control.
ChemInform Abstract: The Optimized Microwave‐Assisted Decomposition of Formamides and Its Synthetic Utility in the Amination Reactions of Purines.
Authors: Cechova Lucie , Jansa Petr , Sala Michal , Dracinsky Martin , Holy Antonin , Janeba Zlatko 
Published: June 2011

AbstractThe main advantages of the present method as compared to the reactions using conventional heating are short reaction times, high yields, simple work‐up.
ChemInform Abstract: Design, Synthesis and Potential 6 Hz Psychomotor Seizure Test Activity of Some Novel 2‐(Substituted)‐3‐{[substituted]amino}quinazolin‐4(3H)‐one.
Authors: Kumar Praveen , Shrivastava Birendra , Pandeya Surendra N. , Stables James P. 
Published: June 2011

AbstractSynthesis and anticonvulsant activity of title compounds (III) and (V) are reported.
ChemInform Abstract: Synthesis and Anticancer Effects of Some Novel Pyrazolo[3,4‐d]pyrimidine Derivatives by Generating Reactive Oxygen Species in Human Breast Adenocarcinoma Cells.
Authors: Rashad Aymn E. , Mahmoud Abeer E. , Ali Mamdouh M. 
Published: June 2011

AbstractSynthesis and in vitro cytotoxicity tests against human breast adenocarcinoma (MCF‐7) are given.
ChemInform Abstract: Stereoselective Synthesis of Oxazino[4,3‐a]indoles Employing the Oxa‐Pictet—Spengler Reaction of Indoles Bearing N‐Tethered Vinylogous Carbonate.
Authors: Gharpure Santosh J. , Sathiyanarayanan A. M. 
Published: June 2011

AbstractA novel strategy for the stereoselective synthesis of N‐fused oxazinoindoles (II) and (IV) employing a TmsOTf mediated oxa‐Pictet—Spengler reaction of vinylogous carbonates (I) and (III).
ChemInform Abstract: Hydrosilylation of Epoxides Catalyzed by a Cationic η1‐Silane Iridium(III) Complex.
Authors: Park Sehoon , Brookhart Maurice 
Published: June 2011

AbstractA cationic silane complex, generated in situ from the depicted Ir‐acetone complex, catalyzes the hydrosilylation of epoxides (I), (IV), (VI), (VIII), and (X) as well as cyclic ethers, such as (XIII), to afford the silyl‐protected alcohols, regioselectively.
ChemInform Abstract: An Expeditious Asymmetric Synthesis of the Pentacyclic Core of the Cortistatins by an Intramolecular [4 + 3] Cycloaddition.
Authors: Liu Lok Lok , Chiu Pauline 
Published: June 2011

AbstractKey step in the described synthesis of cortistatins, a family of rearranged steroidal alkaloids, is the highly diastereoselective intramolecular [4 + 3] cycloaddition of epoxy enolsilane (I).
ChemInform Abstract: Synthesis of 2‐Acetyl‐5‐(1,2,3,4,5,6‐hexahydroxyhexyl)thiazoles.
Authors: Ung Alison T. , Pyne Stephen G. , Jeoffreys George R. , Skelton Brian W. , White Allan H. 
Published: June 2011

AbstractThe synthesis of two diastereomers of the title compound involves the coupling of 5‐lithiated 2‐(1,1‐dimethoxyethyl)thiazole (VI) with a Weinreb amide (V) derived from gluconolacetone, followed by asymmetric reduction of the ketone functionality.
ChemInform Abstract: Alkyne‐Mediated Domino Hydroformylation/Double Cyclization: Mechanistic Insight and Synthesis of (.+‐.)‐Tashiromine.
Authors: Chiou Wen‐Hua , Lin Yi‐Huei , Chen Guei‐Tang , Gao Yu‐Kai , Tseng Yu‐Che , Kao Chien‐Lun , Tsai Jui‐Chi 
Published: June 2011

AbstractThe title reaction allows the rapid preparation of indolizidine type alkaloids.
ChemInform Abstract: Stereoselective First Total Synthesis, Confirmation of the Absolute Configuration and Bioevaluation of Botryolide‐E.
Authors: Reddy D. Kumar , Shekhar V. , Prabhakar P. , Babu D. Chanti , Ramesh D. , Siddhardha B. , Murthy U. S. N. , Venkateswarlu Y. 
Published: June 2011

AbstractBotryolide‐E (I) shows potent activity against S.
Prüfung der Druckfestigkeit von Außenputz auf Mauerwerk
Authors: Schubert Peter 
Published: June 2011

AbstractAußenputz muss in wichtigen Eigenschaften auf den Putzgrund, vor allem bei wärmedämmendem Leichtziegel‐Mauerwerk, angepasst sein, damit schädliche Putzrisse bis in den Putzgrund vermieden werden. Der Nachweis ausreichender Eigenschaftsanpassung kann mit Hilfe der Druckfestigkeit des Putzes auf dem Putzgrund erfolgen. Diese soll etwa 5 N/mm2 nicht überschreiten. Die Druckfestigkeit wird mit den Verfahren II oder III nach DIN 18555‐9, vorzugsweise mit dem Verfahren III an Putzscheiben von am Bauwerk entnommenen Bohrkernen ermittelt. Ein Bezug dieser Druckfestigkeitswerte zu denen an Prismen nach DIN EN 1015‐11 (“Standard”‐Normprüfung, Normdruckfestigkeit) ist möglich. Dadurch lässt sich auch näherungsweise der (obere) Grenzwert der Normdruckfestigkeit bestimmen, bei dem davon ausgegangen werden kann, dass die Putzdruckfestigkeit am Bauwerk den empfohlenen Wert von etwa 5 N/mm2 einhält.Testing the compressive strength of external rendering on masonry. The important properties of external renderings have to be adapted to the respective rendering base, especially in case of masonry made of high thermal insolating light clay units, to avoid unintentional crack formation in the rendering extending into the rendering base. A criterion for the adaptation between rendering and base is the compressive strength of the rendering, which should not exceed 5 N/mm2. The compressive strength of the rendering can be tested according to DIN 18555‐9, test method II or III. Preferably, it should be determined with test method III by use of small plates of the rendering taken from drilled masonry samples. A relation of these compressive strength values to values tested on prisms (standard test method according to DIN EN 1015‐11) does exist. Thus, the upper limit value of the compressive strength tested on prisms can approximately be determined, with which it can be assumed that the compressive strength of the rendering on the masonry wall does not exceed the recommended value of 5 N/mm2.
Komfort und Luftqualität im Niedrigenergie‐Ziegelgebäude
Authors: Keul Alexander , Salzmann Roland , Lehmden Alexander 
Published: June 2011

AbstractFür Ziegel als Baustoff wird mit Wohlbefinden, Komfortklima und Nachhaltigkeit geworben. Beim derzeitigen Aufschwung von Niedrigenergie‐ und Passivhausprojekten macht es Sinn, subjektiv wahrnehmbare Wohneigenschaften mittels Evaluation zu testen. Bisherige Ergebnisse aus Österreich zeigen, dass Wohnentscheidungen für großvolumige Niedrigenergie‐Wohnformen von Lage und Objekteigenschaften, aber kaum von der Energieeinsparung abhängen. Im Folgenden wird über eine Salzburger Wohnhausanlage in Ziegelbauweise nach Niedrigenergie‐Standard berichtet, die mit Tagebüchern, Datenloggern und CO2‐Messgerät evaluiert wurde. Der thermisch‐hygrische Komfort der Ziegelhauswohnungen erschien dabei objektiv wie subjektiv sehr gut; die Luftqualität variierte je nach Familiengröße und Lebensstil.Comfort and air quality in low energy brick buildings. Brick is advertised as a building material for well‐being, indoor climate comfort and sustainability. In the present boom of low‐energy and passive housing projects it makes sense to test subjective, perceptible housing attributes via evaluation. Results from Austria show that housing decisions for large‐volume low energy housing forms focus on site and object qualities, not on energy saving. The following report is on a Salzburg City (Austria) clay brick housing estate with low‐energy standard which was evaluated via user diaries, data logger and with a carbon dioxide measuring instrument. The thermal and hygrometric comfort of the brick apartments was very good according to measurements and diaries; the air quality varied due to family size and life‐style.
DIN 4102‐4 — Eurocodes: Die Zukunft des Brandschutzes
Authors: Hahn Christiane 
Published: June 2011

AbstractBisher war DIN 4102‐4 in Deutschland das Praxis‐Handbuch im Brandschutz zum Nachweis von Baustoffen und Bauprodukten. Aufgrund der Eurocodes für tragende Bauteile, bei denen jeweils im Teil ‐1‐2 die Bemessung im Brandfall erfolgt, gibt es teilweise parallele Regelungen als auch neue Bemessungsverfahren. DIN 4102‐4 musste daher überarbeitet werden. Da die abschließende Gemeinschaftsitzung — DIN 4102‐4 und konstruktiver baulicher Brandschutz — erst nach Redaktionsschluss für dieses Heft stattfindet, kann an dieser Stelle vorab nur kurz über die Planungen berichtet werden.DIN 4102‐4 — Eurocodes: The future of fire protection. So far, DIN 4102‐4 was the practice manual for fire protection for the assessment of building materials and products in Germany. Because of the Eurocodes for structural components, the policy is that in each Part ‐1‐2 the design in case of fire will be done, there is some parallel schemes and new design procedures. DIN 4102‐4 had to be revised. As the final meeting between DIN 4102‐4 and constructive structural fire protection is after the deadline for this issue, at this point can be pre‐reported briefly on the plans.
Zweischalige Außenwände aus Mauerwerk — Auswirkungen des Wärmeschutzes auf den Brandschutz
Authors: Hahn Christiane 
Published: June 2011

AbstractDIN 4102‐4 wird um Brandschutzregeln zu zweischaligem Mauerwerk mit oder ohne Dämmschicht ergänzt. Aufgrund der heute geltenden Vorschriften zum Wärmeschutz werden die Dämmschichten zwischen den zwei Schalen von Außenwänden aus Mauerwerk immer dicker. Aus Gründen der Wirtschaftlichkeit werden häufig brennbare Dämmungen gewählt.In allen Landesbauordnungen werden schon immer brandschutztechnische Anforderungen an Außenwände gestellt. Brandschutznachweise dazu waren aber nicht geregelt. Es wurde daher eine Brandprüfung in der MFPA Leipzig (Gesellschaft für Materialforschung und Prüfungsanstalt für das Bauwesen Leipzig mbH) an einer realen Fassade durchgeführt, um auch Regeln für zweischalige Außenwände mit brennbarer Dämmung aufnehmen zu können.Im Beitrag wird über die Brandprüfung berichtet, und es werden die Diskussionen zu dem Ergebnis sowie die Festlegungen und Randbedingungen zur Ausführung vorgestellt.External doubleleaf masonry walls — Effects of the thermal insulation on fire protection. The thickness of the insulation in cavities increases due to thermal requirements. Combustible insulation materials are widely used. Information about the fire behavior of that type of construction (especially flame transfer through the cavity) was not available. A fire test on a typical cavity‐wall structure was carried out at MFPA Leipzig. Test results are presented and conclusions are given. Additional rules for the evaluation of cavity walls in DIN 4102‐4 are presented.
Moving sound source localization based on sequential subspace estimation in actual room environments
Authors: Tsuji Daisuke , Suyama Kenji 
Published: June 2011

AbstractThis paper presents a novel method for moving sound source localization and describes its performance evaluation in actual room environments. The method is based on MUSIC (MUltiple SIgnal Classification) which is one of the highest‐resolution localization methods. When using MUSIC, computation of eigenvectors of correlation matrix is required for estimation, which often results in a high computational cost. In particular, in the case of a moving source, this is a crucial drawback, because estimation must be performed at every observation time. Furthermore, since the correlation matrix varies its characteristics due to spatial‐temporal nonstationarity, the matrix must be estimated using only a few observed samples, which degrades the estimation accuracy. In this paper, PAST (Projection Approximation Subspace Tracking) is applied for sequential estimation of the eigenvectors spanning the subspace. In PAST, eigen‐decomposition is not required, and therefore it is possible to reduce the computational costs. Several experimental results in actual room environments are presented in order to demonstrate the superior performance of the proposed method. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(7): 17–26, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10333
Pyrrolopyrrole Cyanines: Effect of Substituents on Optical Properties (Eur. J. Org. Chem. 19/2011)
Authors: Fischer Georg M. , Klein Matthias K. , Daltrozzo Ewald , Zumbusch Andreas 
Published: June 2011

AbstractThe cover picture shows a series of selected absorption spectra (solid lines) from different substituted pyrrolopyrrole cyanine (PPCy) dyes. This is a new class of chromophores recently developed at the University of Konstanz, located at Lake Constance (upper left). PPCys feature preciously unattainable high fluorescence quantum yields in the near infrared region, which besides other applications makes them attractive as fluorescence labels. One emission spectrum is shown as a dotted line. The core structure of the PPCys is depicted in the upper right corner. Proper substitutions of the core structure allow the generation of dyes absorbing over a broad wavelength range. Details are discussed in the article by A. Zumbusch et al. on p. 3421 ff.
Electrospray ionization ion‐trap multiple‐stage mass spectrometry of Quillaja saponins
Authors: Bankefors Johan , Broberg Susanna , Nord Lars I. , Kenne Lennart 
Published: June 2011

AbstractFifteen identified C‐18 fatty acyl‐containing saponin structures from Quillaja saponaria Molina have been investigated by electrospray ionization ion‐trap multiple‐stage mass spectrometry (ESI‐IT‐MSn) in positive ion mode. Their MS1–MS3 spectra were analyzed and ions corresponding to useful fragments, important for the structural identification of Quillaja saponins, were recognized. A few key fragments could describe the structural variations in the C‐3 and the C‐28 oligosaccharides of the Quillaja saponins. A flowchart involving a stepwise procedure based on key fragments from the MS1–MS3 spectra of these saponins, together with key fragments from these saponins and 13 previously investigated saponins, was constructed for the identification of structural elements in Quillaja saponins. Peak intensity ratios in MS3 spectra were found to be correlated to structural features of the investigated saponins and is therefore of value for the identification of regioisomers. Copyright © 2011 John Wiley & Sons, Ltd.
A well‐established Early–Middle Pleistocene marine sequence on south‐east Zakynthos island, western Greece: Magneto‐biostratigraphic constraints and palaeoclimatic implications
Authors: Papanikolaou Maria D. , Triantaphyllou Maria V. , Platzman Ellen S. , Gibbard Philip L. , Niocaill Conall Mac , Head Martin J. 
Published: June 2011

AbstractThe chronostratigraphy of a long, onshore Early–Middle Pleistocene marine sedimentary sequence on the south‐east part of Zakynthos island, Greece, is presented. Correlation of the succession with the isotope record of Ocean Drilling Program Site 963 reveals the combined influence of tectonics and eustacy in this area. The sequence is divided into three formations by two main unconformities that apparently relate to sea‐level lowstands associated with two major northern hemisphere glaciations, those of marine isotope stages (MIS) 22 and 12. The Zakynthos sequence in many ways is comparable with the Italian Valle di Manche section. Magnetostratigraphic and rock magnetic analyses, supported by biostratigraphy, document the position of the Matuyama/Brunhes Chron boundary (0.77 Ma), the top and base of the Jaramillo Subchron (0.99–1.07 Ma), the Cobb Mountain Subchron (1.173–1.185 Ma) and the top of the Olduvai Subchron (1.78 Ma). The underlying strata are constrained exclusively by detailed nannofossil biostratigraphy extending at least to the lowermost Pleistocene at around 2.54 Ma and therefore certainly incorporating the base of the Olduvai Subchron (1.95 Ma) and possibly the Gauss/Matuyama Chron boundary (2.58 Ma). In addition, a remarkable increase in sedimentation rate (from 3.2 and 28 cm ka−1 to 167 cm ka−1) and hence resolution above the Matuyama/Brunhes boundary (Middle Pleistocene) reveals one short‐lived magnetic excursion, possibly 17a (0.66 Ma), within the normal polarity Brunhes Chron. Copyright © 2011 John Wiley & Sons, Ltd.