bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subunit positioning and diversity of the nematode levamisole-sensitive acetylcholine receptor
Authors: Noonan JD , Duguet TB , Handy-Hart CJ , Beech RN 
Published: May 2024

AbstractThe helminth levamisole-sensitive acetylcholine receptor (L-AChR) is a historically significant drug target. This heteromeric receptor belongs to the larger class of pentameric ligand-gated ion channels that has recently expanded within the nematodes and therefore provides the opportunity to study specific examples of how worm receptors evolve. TheCaenorhabditis elegansL-AChR can exist in two forms. The first contains three alpha subunits: ACR-13, UNC-38, and UNC-63, and two non-alpha subunits UNC-29 and LEV-1. The second can be formed by replacing ACR-13 with its paralog ACR-8, from eitherC. elegansor the closely relatedHaemonchus contortus.This form no longer requires LEV-1, demonstrating an evolved functional difference between ACR-8 and ACR-13. Since the properties of a channel depend on its composition and organization, knowing the underlying mechanisms regulating this would provide valuable insight into one of the least understood aspects of this important drug target. The goal of this study was to identify the subunit stoichiometry of the L-AChR and further elucidate the functional divergence of alpha subunits ACR-8 and ACR-13. Using a series of subunit concatemers, we determined the arrangement of threeC. elegansL-AChR subunits in the following N- to C-terminal order; UNC-38 – LEV-1 – UNC-63. We were unable to order the ACR-13 and UNC-29 subunits unambiguously. Additionally, our concatemers provide support for the sequential model of subunit assembly whereby a trimer is formed first, consisting of UNC-38 – LEV-1 – UNC-63, followed by individual addition of the remaining two subunits ACR-13 and UNC-29. UsingC. elegansandH. contortussubunit admixtures, we show that replacing ACR-13 with ACR-8 alleviates the requirement for five distinct subunits, as a functional receptor can be measured in the absence of non-alpha LEV-1. We confirm that UNC-29 can replace LEV-1 and that the intracellular loop determines this positional plasticity. This work provides the first evidence of the quaternary structure of the L-AChR which is necessary for future studies on this drug target. It also confirms that subunit arrangement is determined first during receptor heteromerization, followed by functional fine-tuning once subunit types have defined positions.
Health literacy in parents of children with Down syndrome
Authors: Akça Gülfer , Sanri Aslihan , Akca Unal 
Published: May 2024

Purpose
This study aims to evaluate the health literacy level of the parents of children diagnosed with Down syndrome (DS) within one institution in Turkey.

Design/methodology/approach
A cross-sectional survey measuring demographics, information of the child and the parent and health literacy was administered to participants. The health literacy levels in the study were measured with the European Health Literacy Scale (EHLS), which consists of 47 questions.

Findings
Of the 65 participants who completed the questionnaire, 56.9% were mothers, 68.1% were diagnosed in the neonatal outpatient clinic examination after birth, and 58.5% stayed in the neonatal intensive care unit after birth. The mean score of the IHLS scale was 25.06 ± 6.59. Of the parents, 63.1% were found to be inadequate, 18.5% problematic-limited, and 18.5% adequate health literate. Any parent with excellent health literacy level was identified. High education level (p < 0.001), high income level (p < 0.001), living in the city center (p < 0.05), planned pregnancy (p < 0.05) and being a health worker (p < 0.001) were found to be statistically significant with a high EHSL score.

Research limitations/implications
The presence of Down syndrome (DS) in a child also necessitates ongoing monitoring for a range of conditions, including eye diseases and heart disease. Some surgical procedures, such as heart or gastrointestinal surgeries, may also be required. Additionally, the child may require the administration of various medications. Finally, due to the potential lifelong need for assistance, the child may require the support of an adult throughout their lifetime. This is because of the child's inability to live independently due to their mental state. Therefore, parent education is the most important issue in the follow-up of the disease.

Practical implications
To the best of the authors’ knowledge, this is the first study to determine that parents of children diagnosed with DS have very limited knowledge of the disease and health literacy. Explanation of current diseases, treatments and training of parents should also be included in genetic counseling.

Social implications
DS is a chromosomal disease that requires multidisciplinary care. Parents have to know the course of the disease and its complications.

Originality/value
The findings of this study indicate that parents of children with Down syndrome exhibit a profound lack of knowledge regarding the nature of their child's condition and the available healthcare options. It is therefore imperative that genetic counseling incorporates an explanation of the diagnosed diseases, treatments, and educational resources for parents.
Peer health coach experiences promoting a nondiet approach in a university health coaching program
Authors: Lee Saemi , Lima Fogaca Janaina , Papini Natalie , Joseph Courtney , Squires Nikole , Clifford Dawn , Lee Jonathan 
Published: May 2024

PurposeResearch shows peer health education programs on university campuses can support students in pursuing sustainable health-related behavior changes. However, few programs deliver peer health education through a nondiet, weight-inclusive framework. Research shows that health educators who challenge the status quo of diet culture and weight-focused health interventions may face unique challenges when sharing this perspective with others. Thus, the purpose of this study was to examine the experiences of peer educators who provided critical health education by introducing a nondiet, weight-inclusive approach to health.Design/methodology/approachFive health coaches from a university health coaching program at a mid-sized southwestern university participated in a semi-structured interview. The data were analyzed through interpretative phenomenological analysis.FindingsPeer educators faced numerous challenges when introducing nondiet, weight-inclusive approaches such as lacking credibility as a peer to challenge weight-centric messages, feeling conflicted about honoring clients’ autonomy when clients are resistant to a weight-inclusive approach and feeling uncomfortable when discussing client vulnerabilities. Peer educators also identified several strategies that helped them navigate these challenges such as being intentional with social media, using motivational interviewing to unpack clients’ concerns about weight, and seeking group supervision.Originality/valueGiven the reality that health coaches will face challenges sharing weight-inclusive health approaches, educators and supervisors should explicitly incorporate strategies and training methods to help peer health coaches prepare for and cope with such challenges. More research is also needed to examine effective ways to introduce weight-inclusive approaches to college students.
Comparing the antecedents of manager’s and employee’s job satisfaction in the housekeeping department
Authors: Zhang Yunxuan Carrie , Zemke Dina M.V. , Belarmino Amanda , Shum Cass 
Published: May 2024

PurposeJob satisfaction is essential in understanding turnover intentions. Previous studies reveal that highly educated hospitality employees generally have lower levels of job satisfaction, indicating that the antecedents of job satisfaction may be different from hospitality managers and frontline employees. This study compared the different antecedents of job satisfaction for housekeeping managers and employees.Design/methodology/approachThis study used a mixed-methods approach for a two-part study. The researchers recruited housekeeping managers for the exploratory survey. The results of open-end questions helped us build a custom dictionary for the text mining of comments from Glassdoor.com. Finally, a multilinear regression of themes from housekeeping employees’ ratings on Glassdoor.com was conducted to understand the antecedents of job satisfaction for housekeeping managers and employees.FindingsThe results of the exploratory survey indicated that the housekeeping department has an urgent need for organizational support and training. The text-mining revealed organizational support impacts both managers and frontline employees, while training impacts managers more than employees. Finally, the regression analysis showed compensation, business outlook, senior management, and career opportunity impacted both groups. However, work-life balance only influenced managers.Originality/valueWith a large number of employees at low salaries, housekeeping departments have a higher-than-average turnover rate for lodging. This study is among the first to compare the antecedents of managers’ and frontline employees’ job satisfaction in the housekeeping department, extending Social Exchange Theory. It provides suggestions for the housekeeping department to decrease turnover intentions.
How the Metaverse can add new layers of hospitality services: a perspective of senior industry practitioners
Authors: Ashton Mark , Filimonau Viachaslau , Tuomi Aarni 
Published: May 2024

Purpose
Although virtual worlds, such as the Metaverse, can disrupt the hospitality sector, few empirical investigations have critically evaluated the scope and scale of this disruption from an industry perspective. This study aims to rectify this knowledge gap by exploring the opportunities and challenges of the Metaverse as seen by hospitality professionals.

Design/methodology/approach
This is a Delphi study conducted with UK-based senior hospitality industry practitioners experienced in designing and implementing digital innovations within their organisations.

Findings
The Metaverse is most likely to be adopted by hospitality organisations willing and able to take risks, such as large and/or chain-affiliated enterprises. The Metaverse will not replace traditional hospitality services but supplement and enhance them with new layers of service. The main applications are in the context of events and experiences. The Metaverse will also provide the “try before you buy” option, revealing the opportunities to design digital twins of physical businesses. Young and technology-savvy individuals are most likely to first adopt the Metaverse. The key challenges of the adoption are attributed to the technological unpreparedness of hospitality organisations; market immaturity; inflated customer expectations; a skills gap among hospitality employees; and regulatory issues. These challenges require the engagement of various stakeholders to create an operational and monitoring framework for hospitality organisations to embrace the Metaverse.

Practical implications
This study highlights how the Metaverse can disrupt the hospitality industry at the level of strategic planning and business operations.

Originality/value
To the best of the authors’ knowledge, this is one of the first empirical investigations of the potential of the Metaverse from the viewpoint of hospitality industry practitioners.
Routine dynamics and sociomateriality: insights into technological artifacts and their roles
Authors: Costa Júnior Júlio César da , Nascimento Leandro da Silva , Silva Magda Vanessa Souza da , Jerônimo Taciana de Barros 
Published: May 2024

Purpose
This paper aims to discuss artifacts and how they influence the performative scheme of the routine and human agency. Artifacts emerge from a heterogeneous network of technical and social elements, which implies assuming that they strongly influence the performance of a routine and the organizing.

Design/methodology/approach
This essay starts from an established theoretical framework to develop reflections and propose that the artifacts entangle part of organizational knowledge and that the artifact's role is structured by their enactment in performing a routine, which gives them meaning and a sense of purpose.

Findings
The propositions contribute to theoretical and empirical advances by offering new insights for analysing the role of artifacts in routine dynamics. The main arguments presented are about (i) the existence of a potential role and a performed role for artifacts, (ii) that the artifacts' role evolves from knowledge and know-how embedded in routines and their actants and (iii) that artifacts are connected through networks of routines, and they embed a vast repertoire of knowledge and expertise.

Originality/value
Also, it proposes a fruitful research agenda based on the main reflections. Finally, the thoughts presented open a pandora's box to reflect on the intertwining between human and artifacts, not just in organizing but also in everyday social life.
Art galleries usage of artificial intelligence
Authors: Ratten Vanessa 
Published: May 2024

PurposeRecently there has been a surge in interest about the use of artificial intelligence in organisations with art galleries introducing new technological innovations that coincide with the digitalisation revolution. Virtual and immersive environments that are supported by social media and digital platforms are significantly changing customer experiences at art galleries. This is internationalising and making art gallery experiences more accessible thereby fostering the competitive advantage of art galleries.Design/methodology/approachArt gallery customers, stakeholders and managers are appreciating the use of artificial intelligence with resulting higher satisfaction rates. Building on competency and transformational entrepreneurship theory international art gallery managers were interviewed to understand the role of artificial intelligence in their organisations and the impact of internationalisation.FindingsThe data analysis revealed that the internationalisation of art galleries enabled artificial intelligence to transform in person and online visitor experience, work and marketing, and future art gallery development ideas. Results show that artificial intelligence is opening up new transformations derived from entrepreneurial behaviours.Originality/valueKey managerial implications are that art gallery managers need to utilise their international networks in order to learn about artificial intelligence and other new technological innovation. Theoretical implications are that existing theory can be adapted to an art gallery and artificial intelligence context. Limitations and future research suggestions focus on the need to focus more on art galleries as cultural entities that are more likely to utilise new technology innovation such as artificial intelligence.
Firm disruption orientation and supply chain resilience: understanding mechanisms to mitigate disruption impact
Authors: Matas Jose , Perez Nieves , Ruiz Laura , Riquelme-Medina Marta 
Published: May 2024

Purpose
This study aims to investigate the interplay between a proactive attitude towards disruptions – supply chain disruption orientation – and supply chain resilience, increasing our understanding of their influence on reducing the impact of supply chain disruptions within the B2B context.

Design/methodology/approach
As unexpected disruptions are closely related to a dynamic and changing perception of the environment, this research is framed under the dynamic capabilities lens, consistent with existing resilience literature. The authors used partial least squares-path modeling (PLS-PM) to empirically test the proposed research model using survey data from 216 firms.

Findings
Results show that a proactive approach to disruptions alone is insufficient in mitigating their negative impact. Instead, a firm’s disruption orientation plays a crucial role in boosting its resilience, which acts as a mediator, reducing the impact of disruptions.

Originality/value
This paper sheds light on the mechanisms by which firms can mitigate the effects of supply chain disruptions and offers insights into how certain capabilities are needed so that firms’ attitudes can effectively impact firm performance. This research thus suggests that dynamic capabilities, traditionally perceived as being enabled by other elements, act themselves as enablers. Consequently, they have the potential to translate strategic orientation or attitudes into tangible effects on performance, enriching our understanding of how firms combine their internal attitudes and capabilities to achieve sustained competitive advantage.
Corporate cash holding and firm’s performance in times of Ukraine war: a literature review and way forward
Authors: Kumar Neetu , Symss Jacqueline 
Published: May 2024

Purpose
The purpose of the study is to examine factors influencing cash holding of firms during periods of crisis. In recent times, the level of cash holdings in firms has seen a steady rise across industries for diverse reasons. However, the need to study cash holding becomes even more compelling during geopolitical instability as it causes firms to hold greater cash reserves for precautionary reasons.

Design/methodology/approach
This paper systematically reviews literature from 1984 to 2024 by organising the findings thematically based on the relationship between corporate cash holdings (CCH) and firm performance in times of war. The paper used 47 research articles from the Scopus database and Google Scholar. Literature connected to CCH, firm performance and war times was explored. The title and abstract analysis were conducted using VOSviewer software. As a result, the predetermined body of literature was visualised, and six theme-based clusters were identified.

Findings
This paper systematically reviews empirical studies, categorising them into six theme-based groups. These clusters encompass CCH and Determinants, Optimal Cash Holding Levels, Cash Holding Adjustment Speed and Theory, Cash Holding and Firm Value, Cash Holding and Firm Performance, Cash Holding in the Context of the Ukraine War and the adaptive financial strategies of firms in response to economic conditions by using cash holding as a hedging instrument. Inflation prompts adjustments in cash-holding strategies at a macro level. During crises, lower interest rates lead to increased cash holdings. Various motives influence firms’ cash-to-assets ratios. According to the pecking order theory, geopolitical risk negatively affects cash holdings. Exposure to pandemics prompts an increase in cash reserves. War shocks have a profound impact on economies, markets and stability; hence, geographic diversification can reduce the need for precautionary cash. In times of uncertainty, the financial stress of firms can get elevated, and therefore, having a well-diversified geographical portfolio of a firm’s investments can aid in meeting any financially distressing situation.

Originality/value
The literature on CCH has been phenomenal. This paper attempts to structure the issues surrounding cash holding and firm performance in wartime, like the Ukraine war, using the VOSviewer software. This study endeavours to highlight the reasons for cash holding during crises and understand how cash holding affects firm performance. Finally, this paper also tries to comprehend whether cash holding helps as a hedging instrument in times of war.
Linking fear of missing out and psychological well-being: a multi-country study
Authors: Srivastava Shalini , Rishi Bikramjit , Belwal Rakesh 
Published: May 2024

Purpose
This study aims to understand the association between the fear of missing out (FOMO) and its impact on psychological well-being (PWB). The mediating effect of anxiety and moderating effects of social media engagement (SME) and resilience on the association mentioned above are also examined.

Design/methodology/approach
The study used a mix of attachment theory and cognitive-motivational-relational theory to understand the hypothesized relationship using a diverse sample of international respondents from South Asia, South East Asia and the Middle East. The data from 612 respondents was collected using SurveyMonkey. The authors have used Hayes’ PROCESS Macro to test the hypothesised relationships.

Findings
The results revealed that anxiety acts as a mediator between FOMO and PWB, while SME and resilience act as moderators in reducing the impact of FOMO on anxiety and the impact of anxiety on PWB, respectively.

Originality/value
The work extends the existing theorization and points out the merits of using SME and resilience as moderators and anxiety as a mediator for understanding the association between FOMO and PWB.
Examining blockchain adoption determinants and supply chain performance: an empirical study in the logistics and supply chain management industry
Authors: Alkatheeri Hanan , Ahmad Syed Zamberi 
Published: May 2024

Purpose
The purpose of this study is to explore the potential impact of blockchain technology on supply chain performance (SCP). This study further delves into the enablers of blockchain adoption (BA) in SCM and investigates both the direct and mediated effects of blockchain assimilation on garnering a competitive edge in the supply chain and bolstering innovation proficiency, ultimately enhancing SCP.

Design/methodology/approach
This study used a quantitative approach, leveraging partial least squares structural equation modelling. Empirical data were sourced from 500 validated data sets obtained through questionnaires.

Findings
The results indicate that technological readiness and knowledge sharing are key drivers for integrating blockchain into supply chains, with technology readiness displaying a substantially stronger influence. Furthermore, BA significantly enhances supply chain innovation capabilities (SCIC), competitive performance (CP) and overall supply chain efficiency. Notably, both SCIC and CP mediate and amplify the positive effects of blockchain on SCP, emphasising the vital role of innovation and competition in optimising the benefits of blockchain.

Originality/value
To the best of the authors’ knowledge, this study is the first to bridge the gap in the literature connecting SCM and blockchain. The established model augments the theoretical discourse on the SCM-blockchain, offering scholars a validated framework that can be adapted and built upon in future studies.
The support of internal communication during organizational change processes
Authors: Abrantes António Cunha Meneses , Bakenhus Maybritt , Ferreira Aristides Isidoro 
Published: May 2024

PurposeThe literature on communication in change processes, although fundamental, appears to still be very fragmented. The purpose of this study is to provide an explanatory and integrated framework for the communication process in organizational change processes.Design/methodology/approachThe authors conducted 22 semi-structured interviews with employees from 21 companies and 13 different sectors in Germany. The four-step Gioia inductive coding approach was adopted as the methodological approach of the current study.FindingsA final research model reveals that the organizational change communication (OCC) process is marked by specific change-restraining forces associated with the fear of the unknown, habits and convenience. Results also suggest the importance of communication timing and factors that help shape the OCC process, namely the scope, contents and channels of the communication process. Finally, the current research highlights contextual variables of the OCC process, such as credibility or the level of honesty.Originality/valueThe importance of OCC, in particular the understanding of the scope, contents of the message and the channels of communication adopted in the change management process, are important variables in the complexity of change. The paper illustrates the intricacy of communication in change and reinforces the internal and external variables that help shape the OCC process, with implications for change agents and scholars.