bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevención y Manejo de la Trombosis Venosa Profunda en Pacientes Oncológicos
Authors: Tamay Chamba Daniela Fernanda 
Published: April 2024

Introducción: La enfermedad tromboembólica venosa se caracteriza por la formación de un coágulo en el interior de las venas, lo que obstruye el flujo sanguíneo y puede provocar una variedad de síntomas dependiendo de su ubicación. Se ha establecido que los pacientes con cáncer tienen un riesgo más elevado de desarrollar trombosis venosa en comparación con la población general, debido a las complejas interacciones entre factores relacionados con el paciente como el tumor, el tratamiento y ciertos biomarcadores asociados con la enfermedad, esta condición puede tener consecuencias significativas en términos de salud, aumentando el riesgo de mortalidad y generando un impacto económico considerable en el sistema de atención médica. Metodología: Revisión bibliográfica de artículos científicos, publicaciones en revistas científicas. Las bases de datos utilizadas fueron Scielo, Pubmed, Elsevier, Medline, Google. Con antigüedad de 5 años. Resultados: El diagnóstico de la trombosis venosa profunda (TVP) se fundamenta principalmente en la manifestación clínica, y la exploración física; sin embargo, se puede mejorar la precisión diagnóstica al integrar adecuadamente escalas de valoración clínica que clasifica el riesgo de TEV. Conclusiones: El diagnóstico y manejo oportuno de la profilaxis en pacientes oncológicos con trombosis venosa profunda disminuirá la presencia de complicaciones al paciente por ende se evidenciará el decrecientito de mortalidad asociada a esta patología.
Analisis pengaruh kinerja keuangan terhadap cash dividend pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI)
Authors: Tama Fareza Wisnu Aji 
Published: April 2024

This research is intended to know and prove the influence of financial performance towards devident cash on manufacturing industries between 2008 -2011 listed in indonesian stock exchange. And also to measure the degree of influence between financial performance towards cash dividend, thus we used return on investment (ROI) debt to total assets (DTA) and earning per share (EPS) as an indicator that give influence towards cash dividend. We used all manufacturing industries listed in Indonesia stock exchange as a population to calculate the outcome of this research. However, during the research we used purposive sampling method to gather the data and in this case there are 152 companies eligible to be classified as good samples of this research. Then we also used SPSS as a tool to calculate statistical test of regression analysis. Based on the data above, we only found that debt to total assets (H3) did not not prove any significant relationship toward cash dividend. However the rest of the proposed hypothesis (H1, H2, H4 and H5) that consist of return on investment, current ratio and earning per share do have significant relationship toward cash dividend. In the other hand all proposed hypothesis’ have significant and positive relationship toward cash dividend simultaneously. During the statistical calculation we also found that independent variable influences as much as 20,7 % toward cash dividend showed in Adjusted R2 calculation and 79,3 % is influenced by other variables outside this research.
Penerapan sistem reward berbasis kinerja karyawan di Maestro Parfum Yogyakarta
Authors: Utama Surya Wahyu , Prasojo Eko , Kurnianingsih Retno , Pahlevi Reza Widhar 
Published: April 2024

Penelitian ini membahas tentang penerapan sistem reward berbasis kinerja karyawan di Maestro Parfum Yogyakarta. Penelitian ini dilatar belakangi oleh berkembangnya parfum isi ulang dan pengelolaan sumber daya manusia.Penelitian ini merupakan penelitian kualitatif, lokasi yang dijadikan tempat penelitian adalah Maestro Parfum Yogyakarta, adapun yang menjadi subjek penelitian ini adalah seluruh karyawan berjumlah 92 orang, teknik pengumpulan data yang digunakan adalah dengan wawancara. Berdasarkan hasil penelitian dapat disimpulkan bahwa reward yang diberikan Maestro Parfum Yogyakarta memberikan motivasi bagi karyawan dalam bekerja. Reward yang diberikan Maestro Parfum Yogyakarta berupa uang tunai, kenaikan jabatan dan berupa barang.
Perkembangan Hukum dan Kejahatan Siber “Cybercrime” di Indonesia
Authors: Mohamad Revaldy Fairuzzen  , Abil Arya Putra  , Akmal Reihan  , Lilik Prihatini S.H, M.H  
Published: April 2024

Abstract: Technological progress and its implementation have always had a wide impact, both in the context of social life, the development of the business world, and in the evolution of Moral, Ethical, and Legal values. Various technologies are considered to have the potential to fundamentally change the paradigm of global life. The growth of multimedia technology, for example, has resulted in significant developments in the field of telecommunications. This includes not only developments in basic communications, but also involves additional technologies that provide more value. Large penetration of the Internet, if not managed wisely, can lead to the emergence of cybercrime, known as cybercrime or cybercrime, which is a further development of computer crime. Criminal offenses in the realm of information technology are a relatively recent phenomenon, especially when compared to conventional crimes. Information technology crime arose along with the information technology revolution and increasingly physically minimal social interaction, being one of the hallmarks of that revolution. The fight against cybercrime by law enforcement is strongly influenced by the existence of legal regulations. There are several legislations related to information technology, in particular crimes related to the internet, which are regulated in national regulations.
Keywords: Cybercrime, Technology, Development

Abstrak: Kemajuan teknologi beserta implementasinya selalu memiliki dampak yang luas, baik dalam konteks kehidupan sosial, perkembangan dunia bisnis, maupun dalam evolusi nilai-nilai Moral, Etika, dan Hukum. Berbagai teknologi dianggap memiliki potensi untuk mengubah paradigma kehidupan global secara menyeluruh. Pertumbuhan teknologi multimedia, misalnya, telah menghasilkan perkembangan yang signifikan dalam bidang telekomunikasi. Ini tidak hanya mencakup perkembangan dalam komunikasi dasar, tetapi juga melibatkan teknologi tambahan yang memberikan nilai lebih. Penetrasi internet yang besar, jika tidak dikelola dengan bijak, dapat menyebabkan timbulnya kejahatan di dunia maya, dikenal sebagai kejahatan siber atau cyber crime, yang merupakan perkembangan lebih lanjut dari kejahatan komputer. Tindak pidana dalam ranah teknologi informasi merupakan fenomena relatif baru, terutama jika dibandingkan dengan kejahatan konvensional. Kejahatan teknologi informasi muncul seiring dengan revolusi teknologi informasi dan interaksi sosial yang semakin minim secara fisik, menjadi salah satu ciri khas revolusi tersebut.
Penanggulangan kejahatan siber oleh penegak hukum sangat dipengaruhi oleh adanya regulasi hukum. Ada beberapa perundang-undangan yang terkait dengan teknologi informasi, khususnya kejahatan yang terkait dengan internet, yang diatur dalam peraturan nasional.
Kata kunci: Cybercrime, Teknologi, Perkembangan
The Role Of Islamic Religious Education In The Era Of Information And Communication Technology
Authors: Jimi Harianto  
Published: April 2024

Abstract
In the era of globalization, the role of information and communication technology has become very strategic because it presents a world without borders, distance, space and time, and is effective in increasing productivity and efficiency. The Islamic religious education learning process can obtain information, manipulate, manage and exchange knowledge or exchange information more easily. The integration of ICT in educational programs will play an important role in developing students' thinking and developing skills. Increasing teacher professionalism in ICT activities, especially the use of ICT platforms in PAI classes, in order to improve learning and make the education center a center for creative learning, as well as motivation so that students can understand and motivate themselves in learning PAI. In the educational field, ICT programs aim to familiarize students with common ICT information and tools, including computers. Students are expected to understand the terms used in information and communication technology. Apart from helping students learn, the role of information and communication technology inside Education is very influential for teachers, especially in utilizing opportunities to improve teaching strengths.
Keywords: Islamic Religious Education and Information Technology

Abstrak
Di era globalisasi, peran teknologi informasi dan komunikasi menjadi sangat strategis karena menghadirkan dunia tanpa batas, jarak, ruang dan waktu, serta efektif dalam meningkatkan produktivitas dan efisiensi. Proses pembelajaran pendidikan agama Islam dapat memperoleh informasi, memanipulasi, mengelola dan bertukar pengetahuan atau bertukar informasi dengan lebih mudah. Integrasi TIK dalam program pendidikan akan memainkan peran penting dalam mengembangkan pemikiran siswa dan mengembangkan keterampilan. Peningkatan profesionalisme guru dalam kegiatan TIK khususnya penggunaan platform TIK di kelas PAI, guna meningkatkan pembelajaran dan menjadikan pusat pendidikan sebagai pusat pembelajaran yang kreatif, serta motivasi agar peserta didik dapat memahami dan memotivasi diri dalam belajar PAI. Dalam bidang pendidikan, program TIK bertujuan untuk membiasakan siswa dengan informasi dan alat TIK yang umum, termasuk komputer. Siswa diharapkan dapat memahami istilah-istilah yang digunakan dalam teknologi informasi dan komunikasi. Selain membantu siswa belajar, peran teknologi informasi dan komunikasi di dalam dunia pendidikan sangat berpengaruh bagi para guru, terutama dalam memanfaatkan peluang untuk meningkatkan kemampuan mengajar.
Kata Kunci: Pendidikan Agama Islam dan Teknologi Informasi
Maraknya Permohonan Pengesahan Perkawinan di Kota Banjarmasin Kalimantan Selatan
Authors: Gusti Muzainah  , Miftah Faridh  
Published: April 2024

Abstract
Banjarmasin as a metropolitan city is characterized by a dense population, development of the city center, economy, education, access to technology and information as well as the availability of various infrastructure and entertainment facilities. Progress on these various sides should be directly proportional to the level of obedience to the law, the one is the obligation to register a marriage officially. However, based on data from 2015 until 2019, that there is an increase in applications for marriage isbat at the Banjarmasin City Religious Court. This means, there are still many unregistered marriages. This study aims to determine how the phenomenon of marriage isbat in the city of Banjarmasin as a metropolitan city and the factors. The method of this study is used empirical/field research, and the approach of this study is used the sociology and anthropology of law. The results of this study was indicated that: 1) the phenomenon of marriage isbat in the city of Banjarmasin is dominated by the lower class with economic problems and low education; 2) The most dominant factor is the legal culture of the community that views religious law (classical fiqh) as sufficient of validity criteria in the marriage. Therefore, they consider that the marriage isbat can be proposed at any time as a solution to their unregistered marriage.
Keywords: phenomenon, marriage isbat, metropolitan

Abstrak
Banjarmasin sebagai salah satu kota metropolitan yang ditandai dengan padatnya jumlah penduduk, perkembangan pusat kota, ekonomi, pendidikan, akses teknologi dan informasi serta ketersediaan berbagai infrastruktur dan sarana hiburan. Kemajuan di berbagai sisi tersebut seyogyanya berbanding lurus dengan tingkat ketaatan terhadap hukum, salah satunya kewajiban mencatatkan pernikahan secara resmi. Akan tetapi, berdasarkan data tahun 2015 hingga 2019, terlihat adanya peningkatan pengajuan isbat nikah di Pengadilan Agama Kota Banjarmasin. Ini artinya, masih banyak terdapat pernikahan yang tidak tercatat.Penelitian ini bertujuan mengetahui bagaimana fenomena isbat nikah yang terjadi di kota Banjarmasin sebagai salah satu kota metropolitan dan faktor-faktor yang menyebabkan maraknya hal tersebut. metode yang digunakan adalah penelitian hukum empiris/field research, dan pendekatan yang digunakan adalah pendekatan sosiologi hukum dan antropologi hukum.Hasil dari penelitian ini menunjukkan bahwa: 1) fenomena isbat nikah di kota Banjarmasin didominasi oleh kalangan lower class yang memiliki problematika ekonomi dan renfdahnya pendidikan; 2) faktor paling dominan disebabkan budaya hukum masyarakat yang memandang hukum agama (fikih klasik) sudah cukup memenuhi kriteria keabsahan pernikahan mereka. Akibatnya, mereka menganggap bahwa isbat nikah bisa saja sewaktu-waktu diajukan sebagai solusi pernikahan mereka yang tidak tercatat tersebut.
Kata kunci: fenomena, isbat nikah, metropolitan
Circular RNA circMAN1A2 promotes ovarian cancer progression through the microRNA-135a-3p/IL1RAP/TAK1 pathway
Authors: Li Bo , Hu Chuancui , Zhao Da , Nie Mingchao , Wang Xiaoli 
Published: April 2024

Background
Ovarian cancer (OC) is the most lethal malignancy in women owing to its diagnosis only at the advanced stage. Elucidation of its molecular pathogenesis may help identify new tumor markers and targets for therapy. Circular RNAs (circRNAs) are stable, conserved, and functional biomolecules that can be used as effective biomarkers for various cancers.

Methods
In this study, a potential circRNA related to early diagnosis of OC, circMAN1A2, was analyzed. Overexpression/knockdown of circMAN1A2 in OC cells was used to decipher its effects on cell proliferation with a Cell Counting Kit-8, 5-ethynyl-2’-deoxyuridine (EdU), cell cycle, clone formation, and wound healing assay. RNA pull-down and Dual luciferase assay were used to explain the underlying mechanism by which circMAN1A2 regulates OC cell proliferation. In vivo, the effect of circMAN1A2 in OC was evaluated using nude mouse xenograft experiments.

Results
CircMAN1A2 was highly expressed in OC and promoted proliferation, clone formation, and tumorigenicity of OC cells. In addition, we found that circMAN1A2 acted as a sponge for microRNA (miR)-135a-3p; miR-135a-3p directly targeted the 3’ untranslated region of interleukin 1 receptor accessory protein (IL1RAP) in OC cells, thereby regulating the phosphorylation of transforming growth factor-beta activated kinase 1 (TAK1), which resulted in promotion of OC cell growth.

Conclusions
CircMAN1A2 promotes OC cell proliferation by inhibiting the miR-135a-3p/IL1RAP/TAK1 axis. In conclusion, circMAN1A2 may be a biomarker for early detection of OC and a target for subsequent therapy.
Physical activity and sedentary behavior among school-going adolescents in low- and middle-income countries: insights from the global school-based health survey
Authors: Li Hui , Zhang Wenyu , Yan Jin 
Published: April 2024

BackgroundThe Global School Student Health Survey (GSHS) is being carried out by students in various countries across the globe to advance improved health programs for youth. However, in comparison to high-income countries, adolescents in low- and middle-income countries (LMICs) are generally at an early stage of understanding regarding physical activity (PA) and sedentary behavior (SB), often exhibiting low levels of PA and high levels of SB. Furthermore, there is limited evidence connecting PA and SB in school-going adolescents from LMICs.PurposeThe objective of this review was to synthesize the available evidence regarding PA and sedentary behavior among school-going adolescents in LMICs using data from the GSHS.MethodOn March 18, 2023, a systematic literature search was performed across four electronic databases, namely Web of Science, PubMed, ScienceDirect, and EBSCO with n odaterestrictions. Studies were eligible if they: (1) utilization of data sourced from the Global Student-based Health Survey; (2) exploration of physical activity; (3) specific focus on adolescents; (4) conducted in low- and middle-income countries; (5) study design encompassing observational; (6) published as English journal articles.ResultsAmong the 29 studies included in the analysis, the majority revealed elevated levels of sedentary behavior and diminished levels of PA in low- and middle-income countries. Furthermore, notable disparities in physical engagement and sedentary behavior were noted between male and female adolescents (p< 0.001). Augmented PA among teenagers was observed to correlate with higher consumption of vegetables and fruits (AOR = 1.30; 95% CI [1.13–1.50];p< 0.001), decreased alcohol consumption, and a reduced prevalence of loneliness and depression (aOR 1.37, 95% CI [1.18–1.59]).ConclusionsThe results of this review affirm that in contrast to high-income countries, adolescents in low- and middle-income countries (LMICs) are in the early stages of comprehending physical activity, marked by low levels of PA. Physical activity and sedentary behavior in school-going adolescents from LMICs appear to be influenced by factors such as policies, cultural norms, socioeconomic conditions, as well as gender, and age.
Comparative Phytochemical, In-vitro Anti-Hyperglycemic Activities of Napoleona vogelii Hook & Planch Stem Bark and Cassia occidentalis L. Root Extracts
Authors: CE Anarado , CJO Anarado , NA Okonkwo , OF Obumselu , KJ Anyanna, , OA Ikeh , IA Igbokwe 
Published: April 2024

This work investigated the comparative phytochemical, proximate and anti-hyperglycemic activities of stem bark of Napoleonaea vogelii and root of Cassia occidentals extracts. Stem bark and N. vogelii root of C. occidentalis were cold extracted with methanol, ethyl acetate, and n-hexane. The extracts were subjected to proximate, phytochemical analyses and anti-hyperglycemic assays. The result of proximate analysis revealed that stem bark of N. vogelii was made up of 40.28 ± 0.49 % crude fibre, 37.05 ± 0.05 % carbohydrates, 7.45 ± 0.45 % protein and more than 6.00 % oil content. whereas 22.33±0.08 % crude fibre, 44.70± 0.93 % carbohydrates, 10.72± 0.05 % protein and 11.00± 0.00 % oil contents in roots of C. occidentalis. Alkaloids and terpenoids were present in all the extracts of N. vogelii and C. occidentalis. Flavonoids were also found in all extracts of N. vogelii, whereas tannins and glycosides were also found in all extracts of C. occidentalis. In vitro antidiabetic screening of the methanol extracts indicated that both plants showed a good concentration-dependent percentage glucose uptake. In all concentrations, extracts of C. occidentalis exhibited better glucose uptake than N. vogelii extracts. comparable to the activity of the standard drug- metronidazole (68.44±0.00 %), From 0.10 – 0.50 mg/mL, the methanol extracts of both plants also showed a dose-dependent α-amylase inhibitory effect. But the inhibition decreased as the concentration was increased to 1.00 mg/mL. At 0.50 mg/mL, C. occidentalis and N. vogelii showed percentage inhibitory effect of 50.02±0.035 and35.61±0.01. Both plants’ extracts showed good anti-hyperglycemic activity, which may be due to the presence of alkaloids, terpenoids, saponins and tannins in the extracts, validating the folkloric use of both plants in the treatment of diabetes, and thus are good anti-diabetic agents.
Why is benzyl‐gem‐diacetate remarkably stable in aqueous solution?
Authors: Jagannadham V. , Padmavathi D. Annapurna , Sanjeev R. 
Published: May 2009

AbstractBenzyl‐gem‐diacetate is synthesized and performed its solvolysis in water at 25°C. It did not solvolize even for a year, whereas its counterparts benzyl‐gem‐diazide and dihalides underwent spontaneous cleavage through a SN1 mechanism in aqueous solution to give benzaldehydes as the final product through α‐azido benzyl and α‐halo benzyl carbocation intermediates, respectively. The possible explanations are offered for the extraordinary stability of the benzyl‐gem‐diacetate in water. © 2009 Wiley Periodicals, Inc. Int J Chem Kinet 41: 554–557, 2009
Enzymatic Digestion of Single DNA Molecules Anchored on Nanogold-Modified Surfaces
Authors: Lü Junhong , Ye Ming , Duan Na , Li Bin 
Published: May 2009

Abstract
To study enzyme–DNA interactions at single molecular level, both the attachment points and the immediate surroundings of surfaces must be carefully considered such that they do not compromise the structural information and biological properties of the sample under investigation. The present work demonstrates the feasibility of enzymatic digestion of single DNA molecules attached to nanoparticle-modified surfaces. With Nanogold linking DNA to the mica surface by electrostatic interactions, advantageous conditions with fewer effects on the length and topography of DNA are obtained, and an appropriate environment for the activities of DNA is created. We demonstrate that by using Dip-Pen Nanolithography, individual DNA molecules attached to modified mica surfaces can be efficiently digested by DNase I.
Cobalt and Nickel Nanopillars on Aluminium Substrates by Direct Current Electrodeposition Process
Authors: Santos A , Vojkuvka L , Pallarés J , Ferré-Borrull J , Marsal LF 
Published: May 2009

Abstract
A fast and cost-effective technique is applied for fabricating cobalt and nickel nanopillars on aluminium substrates. By applying an electrochemical process, the aluminium oxide barrier layer is removed from the pore bottom tips of nanoporous anodic alumina templates. So, cobalt and nickel nanopillars are fabricated into these templates by DC electrodeposition. The resulting nanostructure remains on the aluminium substrate. In this way, this method could be used to fabricate a wide range of nanostructures which could be integrated in new nanodevices.
Modeling premature brain injury and recovery
Authors: Scafidi Joey , Fagel Devon M. , Ment Laura R. , Vaccarino Flora M. 
Published: May 2009

AbstractPremature birth is a growing and significant public health problem because of the large number of infants that survive with neurodevelopmental sequelae from brain injury. Recent advances in neuroimaging have shown that although some neuroanatomical structures are altered, others improve over time. This review outlines recent insights into brain structure and function in these preterm infants at school age and relevant animal models. These animal models have provided scientists with an opportunity to explore in depth the molecular and cellular mechanisms of injury as well as the potential of the brain for recovery. The endogenous potential that the brain has for neurogenesis and gliogenesis, and how environment contributes to recovery, are also outlined. These preclinical models will provide important insights into the genetic and epigenetic mechanisms responsible for variable degrees of injury and recovery, permitting the exploration of targeted therapies to facilitate recovery in the developing preterm brain.
Suppressing feelings: A double‐edged sword to consumer judgment and choice
Authors: Qiu Cheng , Lee Yih Hwai , Yeung Catherine W.M. 
Published: May 2009

AbstractConsumers may suppress their feelings toward the attractive looks of products when they wish to minimize the influence of feelings on their judgments and choices. However, this research suggests that feeling suppression may result in a paradoxical reliance on feelings in product judgments and choices, especially when the product performance judgment is difficult to make. Findings from a series of experiments suggest that this paradoxical effect stems from the requisite resource input for feeling suppression and the consequent resource competition with functionality processing which then impairs product performance judgment.