bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between parenting practices and children's dietary intake, activity behavior and development of body mass index: the KOALA Birth Cohort Study
Authors: Gubbels Jessica S , Kremers Stef PJ , Stafleu Annette , de Vries Sanne I , Goldbohm R Alexandra , Dagnelie Pieter C , de Vries Nanne K , van Buuren Stef , Thijs Carel 
Published: March 2011

Abstract

Background
Insights into the effects of energy balance-related parenting practices on children's diet and activity behavior at an early age is warranted to determine which practices should be recommended and to whom. The purpose of this study was to examine child and parent background correlates of energy balance-related parenting practices at age 5, as well as the associations of these practices with children's diet, activity behavior, and body mass index (BMI) development.

Methods
Questionnaire data originated from the KOALA Birth Cohort Study for ages 5 (N = 2026) and 7 (N = 1819). Linear regression analyses were used to examine the association of child and parent background characteristics with parenting practices (i.e., diet- and activity-related restriction, monitoring and stimulation), and to examine the associations between these parenting practices and children's diet (in terms of energy intake, dietary fiber intake, and added sugar intake) and activity behavior (i.e., physical activity and sedentary time) at age 5, as well as BMI development from age 5 to age 7. Moderation analyses were used to examine whether the associations between the parenting practices and child behavior depended on child characteristics.

Results
Several child and parent background characteristics were associated with the parenting practices. Dietary monitoring, stimulation of healthy intake and stimulation of physical activity were associated with desirable energy balance-related behaviors (i.e., dietary intake and/or activity behavior) and desirable BMI development, whereas restriction of sedentary time showed associations with undesirable behaviors and BMI development. Child eating style and weight status, but not child gender or activity style, moderated the associations between parenting practices and behavior. Dietary restriction and monitoring showed weaker, or even undesirable associations for children with a deviant eating style, whereas these practices showed associations with desirable behavior for normal eaters. By contrast, stimulation to eat healthy worked particularly well for children with a deviant eating style or a high BMI.

Conclusion
Although most energy balance-related parenting practices were associated with desirable behaviors, some practices showed associations with undesirable child behavior and weight outcomes. Only parental stimulation showed desirable associations with regard to both diet and activity behavior. The interaction between parenting and child characteristics in the association with behavior calls for parenting that is tailored to the individual child.
Integrated sensitive on-chip ion field effect transistors based on wrinkled InGaAs nanomembranes
Authors: Harazim Stefan M , Feng Ping , Sanchez Samuel , Deneke Christoph , Mei Yongfeng , Schmidt Oliver G 
Published: March 2011

AbstractSelf-organized wrinkling of pre-strained nanomembranes into nanochannels is used to fabricate a fully integrated nanofluidic device for the development of ion field effect transistors (IFETs). Constrained by the structure and shape of the membrane, the deterministic wrinkling process leads to a versatile variation of channel types such as straight two-way channels, three-way branched channels, or even four-way intersection channels. The fabrication of straight channels is well controllable and offers the opportunity to integrate multiple IFET devices into a single chip. Thus, several IFETs are fabricated on a single chip using a III-V semiconductor substrate to control the ion separation and to measure the ion current of a diluted potassium chloride electrolyte solution.
Pool boiling of water-Al2O3 and water-Cu nanofluids on horizontal smooth tubes
Authors: Cieslinski Janusz T , Kaczmarczyk Tomasz Z 
Published: March 2011

AbstractExperimental investigation of heat transfer during pool boiling of two nanofluids, i.e., water-Al2O3 and water-Cu has been carried out. Nanoparticles were tested at the concentration of 0.01%, 0.1%, and 1% by weight. The horizontal smooth copper and stainless steel tubes having 10 mm OD and 0.6 mm wall thickness formed test heater. The experiments have been performed to establish the influence of nanofluids concentration as well as tube surface material on heat transfer characteristics at atmospheric pressure. The results indicate that independent of concentration nanoparticle material (Al2O3 and Cu) has almost no influence on heat transfer coefficient while boiling of water-Al2O3 or water-Cu nanofluids on smooth copper tube. It seems that heater material did not affect the boiling heat transfer in 0.1 wt.% water-Cu nanofluid, nevertheless independent of concentration, distinctly higher heat transfer coefficient was recorded for stainless steel tube than for copper tube for the same heat flux density.
Structural and optical properties of germanium nanostructures on Si(100) and embedded in high-k oxides
Authors: Ray Samit K , Das Samaresh , Singha Raj K , Manna Santanu , Dhar Achintya 
Published: March 2011

AbstractThe structural and optical properties of Ge quantum dots (QDs) grown on Si(001) for mid-infrared photodetector and Ge nanocrystals embedded in oxide matrices for floating gate memory devices are presented. The infrared photoluminescence (PL) signal from Ge islands has been studied at a low temperature. The temperature- and bias-dependent photocurrent spectra of a capped Si/SiGe/Si(001) QDs infrared photodetector device are presented. The properties of Ge nanocrystals of different size and density embedded in high-k matrices grown using radio frequency magnetron sputtering have been studied. Transmission electron micrographs have revealed the formation of isolated spherical Ge nanocrystals in high-k oxide matrix of sizes ranging from 4 to 18 nm. Embedded nanocrystals in high band gap oxides have been found to act as discrete trapping sites for exchanging charge carriers with the conduction channel by direct tunneling that is desired for applications in floating gate memory devices.
A simple and efficient method for isolating small RNAs from different plant species
Authors: Rosas-Cárdenas FlordeFátima , Durán-Figueroa Noé , Vielle-Calzada Jean-Philippe , Cruz-Hernández Andrés , Marsch-Martínez Nayelli , de Folter Stefan 
Published: March 2011

Abstract

Background
Small RNAs emerged over the last decade as key regulators in diverse biological processes in eukaryotic organisms. To identify and study small RNAs, good and efficient protocols are necessary to isolate them, which sometimes may be challenging due to the composition of specific tissues of certain plant species. Here we describe a simple and efficient method to isolate small RNAs from different plant species.

Results
We developed a simple and efficient method to isolate small RNAs from different plant species by first comparing different total RNA extraction protocols, followed by streamlining the best one, finally resulting in a small RNA extraction method that has no need of first total RNA extraction and is not based on the commercially available TRIzol® Reagent or columns. This small RNA extraction method not only works well for plant tissues with high polysaccharide content, like cactus, agave, banana, and tomato, but also for plant species like Arabidopsis or tobacco. Furthermore, the obtained small RNA samples were successfully used in northern blot assays.

Conclusion
Here we provide a simple and efficient method to isolate small RNAs from different plant species, such as cactus, agave, banana, tomato, Arabidopsis, and tobacco, and the small RNAs from this simplified and low cost method is suitable for downstream handling like northern blot assays.
Perforation and abscess formation after radiological placement of a retrievable plastic biliary stent
Authors: Papadopoulou Ioanna , Fotiadis Nicos I , Ahmed Irfan , Thurley Peter , Hutchins Robert R , Fotheringham Tim 
Published: March 2011

Abstract

Introduction
Retrievable plastic biliary stents are usually inserted endoscopically. When endoscopic placement fails, radiological percutaneous transhepatic placement is indicated. We report the occurrence of a case of delayed duodenal perforation with abscess formation after radiological placement of a plastic stent. To the best of our knowledge, this is the first report of this complication after radiological stenting.

Case presentation
A 58-year-old Caucasian man had a mass 30 mm in size in the head of the pancreas and obstructive jaundice. He was referred for radiological insertion of plastic biliary stents after a failed endoscopic attempt. The procedure was uneventful, and the patient was discharged. Two weeks after the procedure, the patient presented with an acute abdomen and signs of sepsis. Computed tomography revealed erosion of the posterior duodenal wall from the plastic stent, and a large retroperitoneal abscess. The abscess was drained under computed tomography guidance, and the migrated stent was removed percutaneously with a snare under fluoroscopic guidance. Our patient had an uneventful recovery and was discharged after a week.

Conclusion
Late retroperitoneal duodenal perforation is a very rare but severe complication of biliary stenting with plastic stents. Gastroenterologists, surgeons and radiologists should all be aware of its existence, clinical presentation and management.
Relationships between the Foot Posture Index and foot kinematics during gait in individuals with and without patellofemoral pain syndrome
Authors: Barton Christian J , Levinger Pazit , Crossley Kay M , Webster Kate E , Menz Hylton B 
Published: March 2011

AbstractBackgroundFoot posture assessment is commonly undertaken in clinical practice for the evaluation of individuals with patellofemoral pain syndrome (PFPS), particularly when considering prescription of foot orthoses. However, the validity of static assessment to provide insight into dynamic function in individuals with PFPS is unclear. This study was designed to evaluate the extent to which a static foot posture measurement tool (the Foot Posture Index ‐ FPI) can provide insight into kinematic variables associated with foot pronation during level walking in individuals with PFPS and asymptomatic controls.MethodsTwenty‐six individuals (5 males, 21 females) with PFPS aged 25.1 ± 4.6 years and 20 control participants (4 males, 16 females) aged 23.4 ± 2.3 years were recruited into the study. Each participant underwent clinical evaluation of the FPI and kinematic analysis of the rearfoot and forefoot during walking using a three‐dimensional motion analysis system. The association of the FPI score with rearfoot eversion, forefoot dorsiflexion, and forefoot abduction kinematic variables (magnitude, timing of peak and range of motion) were evaluated using partial correlation coefficient statistics with gait velocity entered as a covariate.ResultsA more pronated foot type as measured by the FPI was associated with greater peak forefoot abduction (r = 0.502, p = 0.013) and earlier peak rearfoot eversion relative to the laboratory (r = ‐0.440, p = 0.031) in the PFPS group, and greater rearfoot eversion range of motion relative to the laboratory (r = 0.614, p = 0.009) in the control group.ConclusionIn both individuals with and without PFPS, there was fair to moderate association between the FPI and some parameters of dynamic foot function. Inconsistent findings between the PFPS and control groups indicate that pathology may play a role in the relationship between static foot posture and dynamic function. The fair association between pronated foot posture as indicated by the FPI and earlier peak rearfoot eversion relative to the laboratory observed exclusively in those with PFPS is consistent with the biomechanical model of PFPS development. However, prospective studies are required to determine whether this relationship is causal.
New clinical score to diagnose nonalcoholic steatohepatitis in obese patients
Authors: Pulzi Fernanda BU , Cisternas Raul , Melo Murilo R , Ribeiro Cristiane MF , Malheiros Carlos A , Salles João E 
Published: March 2011

Abstract

Background
Nonalcoholic fatty liver disease (NAFLD) is the most frequent disease associated with abnormal liver tests that is characterized by a wide spectrum of liver damage, ranging from simple macro vesicular steatosis to steatohepatitis (NASH), cirrhosis or liver carcinoma. Liver biopsy is the most precise test to differentiate NASH from other stages of NAFLD, but it is an invasive and expensive method. This study aimed to create a clinical laboratory score capable of identify individual with NASH in severely obese patients submitted to bariatric surgery.

Methods
The medical records from 66 patients submitted to gastroplasty were reviewed. Their chemistry profile, abdominal ultrasound (US) and liver biopsy done during the surgical procedure were analyzed. Patients were classified into 2 groups according to liver biopsy: Non-NASH group - those patients without NAFLD or with grade I, II or III steatosis; and NASH group - those with steatohepatitis or fibrosis. The t-test was used to compare each variable with normal distribution between NASH and Non-NASH groups. When comparing proportions of categorical variables, we used chi-square or z-test, where appropriate. A p-value < 0.05 was considered statistically significant.

Results
83% of patients with obesity grades II or III showed NAFLD, and the majority was asymptomatic. Total Cholesterol (TC)≥200 mg/dL, alanine aminotransferase (ALT) ≥30, AST/ALT ratio (AAR)≤ 1, gammaglutaril-transferase (γGT)≥30 U/L and abdominal US, compatible with steatosis, showed association with NASH group. We proposed 2 scores: Complete score (TC, ALT, AAR, γGT and US) and the simplified score, where US was not included. The combination of biochemical and imaging results improved accuracy to 84.4% the recognition of NASH (sensitivity 70%, specificity 88.6%, NPV 91.2%, PPV 63. 6%).

Conclusion
Alterations in TC, ALT, AAR, γGT and US are related to the most risk for NASH. The combination of biochemical and imaging results improved accuracy to 84.4% the recognition of NASH. Additionally, negative final scores exclude the presence of an advanced illness. Using this score, the severity of fatty liver infiltration would be predicted without the risks associated with hepatic biopsy.
An Audit of the Management of Melanoma Patients at Glasgow Royal Infirmary 1998-2003
Authors: Macdonald A , Berry C , Holmes S 
Published: March 2011

Background Melanoma is an important cause of morbidity and mortality. Recently published Scottish Intercollegiate Guideline Network (SIGN) guidelines outline standard management for melanoma patients in Scotland. Methods We audited the management of consecutive patients diagnosed with melanoma in Glasgow Royal Infirmary (1998-2003), using the SIGN guidelines as a gold standard. Results Of 102 patients, 41% were male and 59% were female. The mean ages of men and women were 58 and 50 years respectively. Fifty five per cent of all patients had a superficial spreading melanoma, and the median Breslow thickness was 0.64 mm. The most commonly affected site was the head and neck (29%). Most patients (87%) were referred by their general practitioner, but only 30% were marked as urgent by the referrer, and accordingly the median time to first appointment varied between 20 days (1998) and 52 days (2001). The most frequently noted suspicious feature was irregular pigmentation. The median time to biopsy was 6 days. Seventy-one per cent of patients had an excision biopsy, and of those who did not, most (71%) had lesions on the head and neck. There was poor recording of surgical margins (13%) and histological margins were used to determine the need for re-excision. The SIGN guidelines for re-excision and sentinel lymph node biopsy were closely followed. Conclusion The SIGN guidelines for melanoma have been adhered to in our department, although time to first appointment exceeded national recommendations.
Changing Prevalences of Overweight and Obesity in Primary School Children - a Glimmer of Hope?
Authors: Mcdougall C M , Crum J E 
Published: March 2011

Background The current epidemic of childhood obesity is a growing public health concern. Estimates of the prevalence of obesity are necessary so that secular trends can be monitored and the need for preventative measures assessed. Aims To establish the prevalences of overweight and obesity in Aberdeen primary schoolchildren and to investigate how children have been changing with respect to body fatness during their primary school years. Methods: Retrospective study of two cohorts of school entrants, using height and weight data from school nurse records. Results Data were collected on 1018 children. The prevalence of overweight among children in primary year 1 decreased from 28.7% in 1997/98 to 21.5% in 2001/02 (P<0.01). The mean BMI SD score also significantly decreased in boys from 0.51 in 1997/98 to 0.32 in 2001/02. For the 1997/98 school entrants, the prevalences of overweight and obesity did not change between school entry and the end of primary school. The mean BMI SD score decreased significantly during primary school in boys but not in girls. Conclusion Although childhood overweight and obesity remain major public health concerns, we report a slight improvement in measures of obesity over time, particularly in boys.
The Case of the Septic Fitness Instructor: Exercise Immunology in Action?
Authors: Witherspoon P. , Tatarkowska N , Reid F , Anderson JR 
Published: March 2011

A 20 year old fitness instructor was admitted with abdominal pain and rapidly developed severe systemic inflammatory response syndrome and multi-organ dysfunction requiring ventilation and inotropic support. The cause was a histologically early appendicitis. Investigations excluded any underlying immunological or connective tissue disorder. Intense exercise is known to cause changes in the physiology and function of the immune system. Innate and adaptive immune function, both in cellular numbers and function, has been shown to be impaired. An acute phase response similar to that seen with physical stressors such as sepsis and trauma has also been observed with elevation of pro-inflammatory and anti-inflammatory cytokines. This has led to the ‘open window’ theory of transient immunosuppresion following intense exercise. In this case presented, regular vigorous aerobic exercise was being performed whilst the patient was symptomatic up until 4 hours prior to admission. We propose that exercise induced immunosuppresion and priming of the inflammatory response led to a florid systemic inflammatory response developing and contributed to the rapid progression towards multi-organ dysfunction syndrome.
Hepatitis C Virus Infection in Scotland: Epidemiological Review and Public Health Challenges
Authors: Hutchinson SJ , Roy KM , Wadd S , Bird SM , Taylor A , Anderson E , Shaw L , Codere G , Goldberg DJ 
Published: March 2011

Introduction In 2004, Scotland's Health Minister stated that the hepatitis C virus (HCV) “is one of the most serious and significant public health risks of our generation” Methods To appreciate the prevention and care challenges posed by HCV in Scotland, we reviewed all country-specific data on i) the prevalence of infection among different populations, ii) the numbers infected with HCV, and iii) the current and future HCV disease burden Results An estimated 1% of Scotland's population has HCV; 85-90% of those infected were injecting drug users (IDUs). Reductions in HCV prevalence among young IDUs during the early 1990s suggest that the incidence of HCV had decreased; since then, the absence of further reductions highlight that existing prevention measures are insufficient. Two-thirds of the estimated 37,500 chronically HCV-infected individuals in Scotland remain undiagnosed and two-thirds of this group are former IDUs. An estimated 9,000 former IDUs were living with either moderate or severe HCV disease in 2004; if the current uptake of antiviral therapy continues, this number was estimated to double by 2016. Approximately 1,200 HCV-infected IDUs had developed liver failure by 2004; this figure was predicted to increase to 3,200 by 2020. Conclusions Scotland faces three principal public health challenges: i) the prevention of HCV among current IDUs, ii) the diagnosis of HCV-infected persons, particularly those most in need of therapy to prevent severe HCV disease, and iii) the current and future provision of adequate resources to ensure that the movement of patients through the diagnostic and clinical care pathway is optimal
Cost Savings and Quality Improvement - Single-Use Suture Instruments?
Authors: Harden JL , Hiscox JA 
Published: March 2011

Aim To determine if the instruments found in single-use suture kits are of satisfactory quality when compared with re-useable instruments and to determine the cost implications of changing to these kits. Methods Audit of established practice, followed by trial of new suture kits and their introduction to the department. The new practice was then audited. A cost analysis was conducted. Results The audit showed numerous problems with the traditional suture kits (instruments were breaking or no longer suitable for suturing wounds). A trial of single-use instruments demonstrated them to be high quality and provided new instruments each time. A repeat audit at one year post-introduction demonstrated no identifiable problem with the new suture kits. The subjective impression of staff was of an improvement compared to the old kits. Costs of sterilising suture instruments were determined and it was found that single use suture kits were cost effective. Assuming an average usage of 150 kits per month, at £4.45 each cost for sterilisation, and a total cost of £3.05 each for a single-use suture kit plus dressing pack per patient, this yielded a projected cost saving of £2520.00 per annum. The actual cost saving was £1981.00 that year. The shortfall was due to overestimation of average usage. Conclusion - Single use instruments would appear to be safe and cost effective in the emergency department setting.
Outcome Using a Conservative Tracheostomy Strategy in Intensive Care
Authors: Khanna R , Beynon Ja , Ure Ds 
Published: March 2011

Background and aims We have a conservative approach to tracheostomy in intensive care, in that every patient considered for tracheostomy in our unit is discussed at a clinical meeting to evaluate potential benefit and harm from the procedure. This study examined tracheostomy numbers, complications and outcome of patients who had tracheostomy in comparison to our general intensive care population and to Scottish national data. Methods We collected prospective data on all patients having a tracheostomy over a three year period. Data included included time to tracheostomy, type of procedure (open or percutaneous), ventilator settings immediately before tracheostomy, peri- and post-operative complications and mortality. Results The number of tracheostomies was low (27 of 692 patients, 4%) and time to tracheostomy high (mean, 18 days) in comparison to published data. Patients who had a tracheostomy had a hospital mortality that was greater than predicted by the APACHE II scoring system (55% actual mortality vs. 44% predicted). Standardised mortality ratio (SMR) was 1.29 for tracheostomy patients and 0.89 for patients who did not have a tracheostomy. Length of stay and mortality were similar to national figures. One patient in the tracheostomy group developed tracheal stenosis that needed surgical intervention. There were no cases of symptomatic tracheal stenosis in the much larger group managed with orotracheal intubation alone. Conclusions We found that a conservative approach to performing tracheostomy reduced the number of procedures performed without affecting overall unit outcomes.