bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Response of Taupō Volcano to the M7.8 Kaikōura Earthquake
Authors: Schuler J. , Hreinsdóttir S. , Illsley‐Kemp F. , Holden C. , Townend J. , Villamor P. 
Published: May 2024

AbstractSeveral studies suggest that large earthquakes (M > 7.0) can act as external triggers of volcanic unrest, and even eruption. This triggering is attributed to either ground shaking (dynamic stresses) or to permanent ground deformation (associated with static stress changes). However, large earthquakes are rare and testing triggering hypotheses has proven difficult. We use geodetic data to show that the 13 November 2016 Kaikōura earthquake (Mw 7.8) triggered local deformation of up to 11 mm at Taupō volcano, 500 km away, which lasted for approximately twelve days. Using elastic geodetic models, we infer that the observed deformation was caused by either aseismic fault slip or a dike intrusion. We then use strong motion data from the surrounding area to show that the Kaikōura earthquake caused maximum dynamic stress changes in the range of 0.15–0.9 MPa in the vicinity of Taupō volcano and conclude that these dynamic stress changes triggered local faulting or dike activity and the associated deformation at Taupō volcano.
A Correlated‐K Parameterization for O2 Photolysis in the Schumann‐Runge Bands
Authors: Ji Aoshuang , Tomazzeli Orlando G. , Palancar Gustavo G. , Chaverot Guillaume , Barker Mackenzie , Fernández Rafael P. , Minschwaner Kenneth , Kasting James F. 
Published: May 2024

AbstractA recent study comparing ozone column depths and methane lifetimes at varied atmospheric O2 (pO2) levels calculated in the Kasting‐group 1‐D photochemical model and the Whole Atmosphere Community Climate Model version 6 (WACCM6) 3‐D model (Ji, Kasting, et al., 2023; https://doi.org/10.1098/rsos.230056) has exposed weaknesses in both models in parameterizing photolysis in the O2 Schumann‐Runge bands, 175–205 nm. WACCM6 does a good job for Earth's present atmosphere but neglects scattering, which becomes important at low pO2. The 1‐D model includes scattering but is based on an out‐of‐date band model, and it neglects the temperature dependence of photolysis at low pO2. We have revised and improved the 1‐D photochemical model by replacing the old O2 photolysis algorithm with a new correlated‐k parameterization, which improves accuracy for all O2 levels and all temperature profiles. The WACCM6 parameterization was also included in the 1‐D model for comparative purposes. The correlated‐k and WACCM6 photolysis algorithms agree well for both the present atmosphere and for an atmosphere containing 10−3 times the present O2 level, but only if multiple scattering is included at low pO2. The correlated‐k parameterization will be made available to photochemical modeling groups who might choose to adopt it.
Constraints on Growth and Stabilization of the Western Superior Craton From Inversion of Magnetotelluric Data
Authors: Roots E. A. , Frieman B. M. , Hill G. J. , Smith R. S. , Craven J. A. , Calvert A. J. , Snyder D. B. 
Published: May 2024

AbstractA data set consisting of 376 broadband and long‐period MT measurements was used to generate the first ever 3D resistivity model of the Archean western Superior Craton. The modeled resistivity structure is compared to coincident seismic reflection data. The observed geophysical signatures are interpreted within the context of the late stages of crustal growth and cratonization of the region via the progressive accretion of terranes against the initial cratonic core. The northern‐most terranes comprising the cratonic core exhibit a nearly homogenous highly resistive crust. The lower crust of the southern terranes contains largely continuous low resistivity bands which run subparallel to major terrane boundaries and corresponding fault systems. In some cases, low resistivity features are coincident with dense packages of sub‐horizontal to listric reflections within the mid‐ to lower crust. These resistivity structures are inferred to represent preserved geoelectric signatures of late to post‐orogenic magmatic pulses likely related to delamination of locally overthickened crust. Increased mantle heat flow resulted in partial melting of the lower crust and upper mantle and upward migration of CO2‐rich melts and fluids through crustal weak zones corresponding to shear and/or suture zones formed during terrane amalgamation. Thermal softening of the mid‐ to lower crust led to orogenic collapse and reactivation of the crustal shear zones, resulting in formation and interconnection of graphitic films which were preserved within the stable craton. These results have implications for the tectono‐magmatic history of the western Superior Craton, as well toward the understanding of the geodynamic regime of the Archean Earth.
CO2‐Dependence of Longwave Clear‐Sky Feedback Is Sensitive to Temperature
Authors: Xu Yue , Koll Daniel D. B. 
Published: May 2024

AbstractCO2 absorbs and emits radiation, which allows it to act both as radiative forcing and feedback. Recent work has shown CO2’s feedback effect becomes dominant in hothouse climates, giving rise to a non‐monotonic climate sensitivity around 310 K. However, CO2’s feedback effect in colder climates is less clear. We use a line‐by‐line model to explore the CO2‐dependence of the longwave clear‐sky feedback and identify a dividing temperature. Above 290 K, feedback increases with CO2 concentration; below 290 K, feedback decreases with CO2 concentration. We explain this dependence in terms of spectral competition under CO2 increases. In hot climates, CO2’s moderate feedback replaces near‐zero feedback from the H2O bands; in cold climates, CO2’s moderate feedback replaces the large feedback from the surface. Given that global mean temperature is currently close to 290 K, our results suggest that feedback CO2‐dependence is weak at present but can be important in past and future climates.
Fast and Slow Responses of Atlantic Meridional Overturning Circulation to Antarctic Meltwater Forcing
Authors: Shin Yechul , Geng Xin , Oh Ji‐Hoon , Noh Kyung‐Min , Jin Emilia Kyung , Kug Jong‐Seong 
Published: May 2024

AbstractAntarctic meltwater discharge has been largely emphasized for its potential role in climate change mitigation, not only by reducing global warming, but also by stabilizing the Atlantic Meridional Overturning Circulation (AMOC). Despite the tremendous impact of the AMOC on the climate system, its temporal evolution in response to the meltwater remains poorly understood. Here, we investigate the meltwater impacts on the AMOC based on the GFDL CM2.1 experiments and discover its fast weakening and slow strengthening to the Antarctic meltwater discharge. Cold ocean surface caused by meltwater spread throughout the globe and eventually strengthened the AMOC. However, in the early stages, the tropical temperature response could stimulate the Rossby wave teleconnection, modulating atmospheric circulation in the North Atlantic, and weakening convection and even the AMOC. This counterintuitive evolution implies a potential destabilizing effect of Antarctic meltwater, underscoring the importance of the atmospheric dynamics in the interaction between the two poles.
Decadal Variability of Ice‐Shelf Melting in the Amundsen Sea Driven by Sea‐Ice Freshwater Fluxes
Authors: Haigh Michael , Holland Paul R. 
Published: May 2024

AbstractThe ice streams flowing into the Amundsen Sea, West Antarctica, are losing mass due to changes in oceanic basal melting of their floating ice shelves. Rapid ice‐shelf melting is sustained by the delivery of warm Circumpolar Deep Water to the ice‐shelf cavities, which is first supplied to the continental shelf by an undercurrent that flows eastward along the shelf break. Temporal variability of this undercurrent controls ice‐shelf basal melt variability. Recent work shows that on decadal timescales the undercurrent variability opposes surface wind variability. Using a regional model, we show that undercurrent variability is induced by sea‐ice freshwater fluxes, particularly those north of the shelf break, which affect the cross‐shelf break density gradient. This sea‐ice variability is linked to tropical Pacific variability impacting atmospheric conditions over the Amundsen Sea. Ice‐shelf melting also feeds back onto the undercurrent by affecting the on‐shelf density, thereby influencing shelf‐break density gradient anomalies.
Emerging Influence of Enhanced Greenland Melting on Boundary Currents and Deep Convection Regimes in the Labrador and Irminger Seas
Authors: Schiller‐Weiss Ilana , Martin Torge , Schwarzkopf Franziska U. 
Published: May 2024

AbstractFreshwater input from Greenland ice sheet melt has been increasing in the past decades from warming temperatures. To identify the impacts from enhanced meltwater input into the subpolar North Atlantic from 1997 to 2021, we use output from two nearly identical simulations in the eddy‐rich model VIKING20X (1/20°) only differing in the freshwater input from Greenland: one with realistic interannually varying runoff increasing in the early 2000s and the other with climatologically (1961–2000) continued runoff. The majority of the additional freshwater remains within the boundary current enhancing the density gradient toward the warm and salty interior waters yielding increased current velocities. The accelerated boundary current shows a tendency to enhanced, upstream shifted eddy shedding into the Labrador Sea interior. Further, the experiments allow to attribute higher stratification and shallower mixed layers southwest of Greenland and deeper mixed layers in the Irminger Sea, particularly in 2015–2018, to the runoff increase in the early 2000s.
Particle Scattering in the Presence of Moderate to Strong Adiabatic Focusing
Authors: Florinski V. 
Published: May 2024

AbstractStarting from the Vlasov‐Boltzmann equation, we derive corrections to the quasi linear Fokker‐Planck pitch angle scattering coefficient caused by a non‐uniformity of the background magnetic field. Integration of the perturbed particle distribution function is performed along a modified unperturbed trajectory that takes into account the effects of focusing and mirroring on pitch angle and gyrophase. We calculate the changes to the quasi‐linear scattering rate owing to a variations in the field strength and the gyrophase drift that affects the resonance between particles and magnetic fluctuations. It is shown that the scattering coefficient has an oscillating behavior in pitch angle when the focusing lengthscale is comparable to the correlation length of the turbulence and the particle's Larmor radius. The applicability of analytic results are demonstrated with a simple model of charged particles trapped in a magnetic field of a planet. It is suggested that the pitch angle diffusion coefficient could become negative for the case of very strong focusing.
Population health implications of exposure to pervasive military aircraft noise pollution
Authors: Jacuzzi Giordano , Kuehne Lauren M. , Harvey Anne , Hurley Christine , Wilbur Robert , Seto Edmund , Olden Julian D. 
Published: May 2024

Abstract
Background
While the adverse health effects of civil aircraft noise are relatively well studied, impacts associated with more intense and intermittent noise from military aviation have been rarely assessed. In recent years, increased training at Naval Air Station Whidbey Island, USA has raised concerns regarding the public health and well-being implications of noise from military aviation.

Objective
This study assessed the public health risks of military aircraft noise by developing a systematic workflow that uses acoustic and aircraft operations data to map noise exposure and predict health outcomes at the population scale.

Methods
Acoustic data encompassing seven years of monitoring efforts were integrated with flight operations data for 2020–2021 and a Department of Defense noise simulation model to characterize the noise regime. The model produced contours for day-night, nighttime, and 24-h average levels, which were validated by field monitoring and mapped to yield the estimated noise burden. Established thresholds and exposure-response relationships were used to predict the population subject to potential noise-related health effects, including annoyance, sleep disturbance, hearing impairment, and delays in childhood learning.

Results
Over 74,000 people within the area of aircraft noise exposure were at risk of adverse health effects. Of those exposed, substantial numbers were estimated to be highly annoyed and highly sleep disturbed, and several schools were exposed to levels that place them at risk of delay in childhood learning. Noise in some areas exceeded thresholds established by federal regulations for public health, residential land use and noise mitigation action, as well as the ranges of established exposure-response relationships.

Impact statement
This study quantified the extensive spatial scale and population health burden of noise from military aviation. We employed a novel GIS-based workflow for relating mapped distributions of aircraft noise exposure to a suite of public health outcomes by integrating acoustic monitoring and simulation data with a dasymetric population density map. This approach enables the evaluation of population health impacts due to past, current, and future proposed military operations. Moreover, it can be modified for application to other environmental noise sources and offers an improved open-source tool to assess the population health implications of environmental noise exposure, inform at-risk communities, and guide efforts in noise mitigation and policy governing noise legislation, urban planning, and land use.
Single-structure 3-axis Lorentz force magnetometer based on an AlN-on-Si MEMS resonator
Authors: Tu Cheng , Ou-Yang Xu-heng , Wu Ying-jie , Zhang Xiao-sheng 
Published: May 2024

AbstractThis work presents a single-structure 3-axis Lorentz force magnetometer (LFM) based on an AlN-on-Si MEMS resonator. The operation of the proposed LFM relies on the flexible manipulation of applied excitation currents in different directions and frequencies, enabling the effective actuation of two mechanical vibration modes in a single device for magnetic field measurements in three axes. Specifically, the excited out-of-plane drum-like mode at 277 kHz is used for measuring the x- and y-axis magnetic fields, while the in-plane square-extensional mode at 5.4 MHz is used for measuring the z-axis magnetic field. The different configurations of applied excitation currents ensure good cross-interference immunity among the three axes. Compared to conventional capacitive LFMs, the proposed piezoelectric LFM utilizes strong electromechanical coupling from the AlN layer, which allows it to operate at ambient pressure with a high sensitivity. To understand and analyze the measured results, a novel equivalent circuit model for the proposed LFM is also reported in this work, which serves to separate the effect of Lorentz force from the unwanted capacitive feedthrough. The demonstrated 3-axis LFM exhibits measured magnetic responsivities of 1.74 ppm/mT, 1.83 ppm/mT and 6.75 ppm/mT in the x-, y- and z-axes, respectively, which are comparable to their capacitive counterparts.
Salidroside promotes the repair of spinal cord injury by inhibiting astrocyte polarization, promoting neural stem cell proliferation and neuronal differentiation
Authors: Qian Dingfei , Dong Yuan , Liu Xiaole , Yu Haichao , Song Zelong , Jia Chengqi , Zhang Zhen , Cao Shiqi , Hu Fanqi , Zhang Xuesong 
Published: May 2024

AbstractSpinal cord injury (SCI) remains a formidable challenge, lacking effective treatments. Following SCI, neural stem cells (NSCs) migrate to SCI sites, offering a potential avenue for nerve regeneration, but the effectiveness of this intrinsic repair mechanism remains suboptimal. Salidroside has demonstrated pro-repair attributes in various pathological conditions, including arthritis and cerebral ischemia, and the ability to curtail early-stage inflammation following SCI. However, the specific role of salidroside in the late-stage repair processes of SCI remains less defined. In this investigation, we observed that continuous salidroside treatment in SCI mice improved motor function recovery. Immunofluorescence-staining corroborated salidroside’s capacity to stimulate nerve regeneration and remyelination, suppress glial scar hyperplasia, reduce the activation of neurotoxic A1 astrocytes, and facilitate NSCs migration towards the injured region. Mechanistically, in vitro experiments elucidated salidroside’s significant role in restraining astrocyte proliferation and A1 polarization. It was further established that A1 astrocytes hinder NSCs proliferation while inducing their differentiation into astrocytes. Salidroside effectively ameliorated this inhibition of NSCs proliferation through diminishing c-Jun N-terminal kinase (JNK) pathway phosphorylation and restored their differentiation into neurons by suppressing the signal transducer and activator of transcription 3 (STAT3) pathway. In summary, our findings suggest that salidroside holds promise as a therapeutic agent for traumatic SCI treatment.
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Authors: Prabhu Kirti S. , Ahmad Fareed , Kuttikrishnan Shilpa , Leo Rari , Ali Tayyiba Akbar , Izadi Mahmoud , Mateo Jericha M. , Alam Majid , Ahmad Aamir , Al-Shabeeb Akil Ammira S. , Bhat Ajaz A. , Buddenkotte Joerg , Pourkarimi Ehsan , Steinhoff Martin , Uddin Shahab 
Published: May 2024

AbstractNon-melanoma skin cancer (NMSC), encompassing basal and squamous cell carcinoma, is the most prevalent cancer in the United States. While surgical removal remains the conventional therapy with a 95% 5-year cure rate, there is a growing interest in exploring alternative treatment strategies. In this study, we investigated the role of Bortezomib (BTZ), a proteasome inhibitor, in NMSC. Using two NMSC cell lines (A431 and A388), we examined the effects of BTZ treatment. Our results demonstrated that 48 h of BTZ treatment led to downregulating Skp2 expression in both A431 and A388 cells while upregulating p53 expression, specifically in A388 cells. These alterations resulted in impaired cellular growth and caspase-dependent cell death. Silencing Skp2 in A388 cells with siRNA confirmed the upregulation of p53 as a direct target. Furthermore, BTZ treatment increased the Bax to Bcl-2 ratio, promoting mitochondrial permeability and the subsequent release of cytochrome C, thereby activating caspases. We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. Interestingly, BTZ treatment induced autophagy, which is evident from the increased expression of microtubule-associated proteins nucleoporin p62 and LC-3A/B. In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). Our findings demonstrated that BTZ induced germline apoptosis in worms even at low concentrations. Notably, this increased apoptosis was mediated through the activity of CEP-1, the worm’s counterpart to mammalian p53. In summary, our study elucidated the molecular mechanism underlying BTZ-induced apoptosis in NMSC cell lines and C. elegans. By targeting the skp2/p53 axis, inducing mitochondrial permeability, generating ROS, and promoting autophagy, BTZ demonstrates promising anti-cancer activity in NMSC. These findings provide novel insights into potential therapeutic strategies for controlling the unregulated growth of NMSC.
Implication of thermal signaling in neuronal differentiation revealed by manipulation and measurement of intracellular temperature
Authors: Chuma Shunsuke , Kiyosue Kazuyuki , Akiyama Taishu , Kinoshita Masaki , Shimazaki Yukiho , Uchiyama Seiichi , Sotoma Shingo , Okabe Kohki , Harada Yoshie 
Published: May 2024

AbstractNeuronal differentiation—the development of neurons from neural stem cells—involves neurite outgrowth and is a key process during the development and regeneration of neural functions. In addition to various chemical signaling mechanisms, it has been suggested that thermal stimuli induce neuronal differentiation. However, the function of physiological subcellular thermogenesis during neuronal differentiation remains unknown. Here we create methods to manipulate and observe local intracellular temperature, and investigate the effects of noninvasive temperature changes on neuronal differentiation using neuron-like PC12 cells. Using quantitative heating with an infrared laser, we find an increase in local temperature (especially in the nucleus) facilitates neurite outgrowth. Intracellular thermometry reveals that neuronal differentiation is accompanied by intracellular thermogenesis associated with transcription and translation. Suppression of intracellular temperature increase during neuronal differentiation inhibits neurite outgrowth. Furthermore, spontaneous intracellular temperature elevation is involved in neurite outgrowth of primary mouse cortical neurons. These results offer a model for understanding neuronal differentiation induced by intracellular thermal signaling.
Self-assembly of nanocrystal checkerboard patterns via non-specific interactions
Authors: Wang Yufei , Zhou Yilong , Yang Quanpeng , Basak Rourav , Xie Yu , Le Dong , Fuqua Alexander D. , Shipley Wade , Yam Zachary , Frano Alex , Arya Gaurav , Tao Andrea R. 
Published: May 2024

AbstractCheckerboard lattices—where the resulting structure is open, porous, and highly symmetric—are difficult to create by self-assembly. Synthetic systems that adopt such structures typically rely on shape complementarity and site-specific chemical interactions that are only available to biomolecular systems (e.g., protein, DNA). Here we show the assembly of checkerboard lattices from colloidal nanocrystals that harness the effects of multiple, coupled physical forces at disparate length scales (interfacial, interparticle, and intermolecular) and that do not rely on chemical binding. Colloidal Ag nanocubes were bi-functionalized with mixtures of hydrophilic and hydrophobic surface ligands and subsequently assembled at an air–water interface. Using feedback between molecular dynamics simulations and interfacial assembly experiments, we achieve a periodic checkerboard mesostructure that represents a tiny fraction of the phase space associated with the polymer-grafted nanocrystals used in these experiments. In a broader context, this work expands our knowledge of non-specific nanocrystal interactions and presents a computation-guided strategy for designing self-assembling materials.
Correlating activities and defects in (photo)electrocatalysts using in-situ multi-modal microscopic imaging
Authors: Mesa Camilo A. , Sachs Michael , Pastor Ernest , Gauriot Nicolas , Merryweather Alice J. , Gomez-Gonzalez Miguel A. , Ignatyev Konstantin , Giménez Sixto , Rao Akshay , Durrant James R. , Pandya Raj 
Published: May 2024

AbstractPhoto(electro)catalysts use sunlight to drive chemical reactions such as water splitting. A major factor limiting photocatalyst development is physicochemical heterogeneity which leads to spatially dependent reactivity. To link structure and function in such systems, simultaneous probing of the electrochemical environment at microscopic length scales and a broad range of timescales (ns to s) is required. Here, we address this challenge by developing and applying in-situ (optical) microscopies to map and correlate local electrochemical activity, with hole lifetimes, oxygen vacancy concentrations and photoelectrode crystal structure. Using this multi-modal approach, we study prototypical hematite (α-Fe2O3) photoelectrodes. We demonstrate that regions of α-Fe2O3, adjacent to microstructural cracks have a better photoelectrochemical response and reduced back electron recombination due to an optimal oxygen vacancy concentration, with the film thickness and extended light exposure also influencing local activity. Our work highlights the importance of microscopic mapping to understand activity, in even seemingly homogeneous photoelectrodes.