bluuebunny/crossref_metadata_2025_split huggingface dataset:
A modified complex shifted preconditioner combined with sparse approximate inversion preconditioner for electromagnetic scattering
Authors: Hu X. Q. , Chen M. , Ding D. Z. , Chen R. S. 
Published: November 2010

AbstractTo efficiently solve large, dense, and complex linear systems arising from electric field integral equations formulation of electromagnetic scattering problems, the multilevel fast multipole algorithm is used to accelerate the matrix–vector product operations. This article presents a modified complex shifted preconditioner (MCSP), which is combined with sparse approximate inversion (SAI) preconditioner can greatly improve the convergence of restart generalized minimal residual iterative method for large, dense, complex linear systems. Numerical experiments demonstrate that the MCSP combined with SAI preconditioner is very effective and can reduce the iteration number and the computational time significantly. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:55–58, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25651
Characterization of nonlinearity using polynomial transfer function of all‐optical sampling
Authors: Zhang Shangjian , Liu Yong , Li Heping , Liu Yongzhi 
Published: November 2010

AbstractA novel method for full characterizing nonlinear distortion of all‐optical sampling is proposed based on polynomial transfer function.The method only requires fitting transfer curve with a polynomial function and enables a uniform expression of nonlinear distortion in terms of polynomial coefficients and input parameters. Simulation and experiment are designed and performed to check the accuracy. The results with our method are in good agreement with the measurement. Our method avoids both Fourier expansion and spectrum measurement, which is suitable for fast evaluating and optimizing distortion of all‐optical sampling. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:216–219, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25655
Electro‐optic field probe sensor incorporating a high‐k dielectric with an aperture
Authors: Kyoung Un‐Hwan , Lee Sang‐Shin 
Published: November 2010

AbstractAn electro‐optic field probe sensor relying on a lithium niobate sensing tip, which is integrated with a fiber collimator, was proposed and fabricated. A high‐k dielectric sheet with a circular aperture at the center was placed in front of the sensing tip to concentrate and strengthen the field near the aperture, leading to an improvement in the sensing capability. The applied electrical field/power was successfully estimated from the optical output power from the sensor, which is dependent upon the electro‐optic effect induced phase retardation between the ordinary and extraordinary waves traversing the electro‐optic sensing tip. The completed sensor functioned successfully up to a frequency of 1.2 GHz. The sensor was used to scan a microstrip test circuit to provide the field distribution. The results are in decent agreement with the theoretical results obtained through a HFSS based simulation. Finally, a high‐k sheet with a dielectric constant of up to 90 was introduced, which improved the sensitivity by ∼10 dB. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:151–153, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25658
Novel broadband dual‐polarized dipole antenna
Authors: Huang Hua , Niu Zhongqi , Bai Bing , Zhang Jinfeng 
Published: November 2010

AbstractA novel broadband dual‐polarized cross‐pair dipole antenna is presented in this article.Two pairs of a folded dipole antenna are used as ±45° polarization element, respectively. With such a cross pair of folded dipoles, a polarization diversity antenna is constructed. A prototype antenna has been fabricated and tested. Results of simulation and measurement agree well and show the antenna exhibits encouraging properties, e.g., 10‐dB impedance bandwidth of 87.3% from 800 to 2040 MHz, which is much wider than that of conventional cross‐pair antennas, as well as a half‐power beamwidth within 65 ± 5° in the horizontal plane. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:148–150, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25659
Reflection loss and bandwidth performance of X‐band infinite reflectarrays: Simulations and measurements
Authors: Abbasi Muhammad Inam , Ismail Muhammad Y. 
Published: November 2010

AbstractA technique for the measurement of scattering parameters of an infinite reflectarray is presented which takes into account effects of mutual coupling. Infinite reflectarrays designed at 10 GHz with different substrate thicknesses have been analyzed in which maximum 10% and 20% bandwidth values from resonance are shown to be 157 MHZ and 250 MHz, respectively, constructed on 0.508‐mm thick substrate. Moreover, a figure of merit (FOM) has been defined which decreases from 0.320 to 0.26 °/MHz as the substrate thickness is increased from 0.127 to 0.508 mm, and the results demonstrate a significant decrease in the slope of reflection phase curve. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:77–80, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25662
New and accurate synthesis formulas for asymmetric conductor‐backed coplanar waveguides
Authors: Kaya S. , Guney K. , Yildiz C. , Turkmen M. 
Published: November 2010

AbstractNew and accurate synthesis formulas for the asymmetric conductor‐backed coplanar waveguide (ACBCPW) are presented. They are obtained by using a differential evolution and particle swarm optimization algorithms. The synthesis formulas are useful to microwave engineers for accurately calculating the physical dimensions of ACBCPWs. The results of the synthesis formulas are compared with the quasi‐static analysis, a full‐wave electromagnetic simulator IE3D, and experimental results obtained in this work. The average percentage errors of the synthesis formulas found by using differential evolution and particle swarm optimization algorithms are calculated to be 0.56% and 0.93%, respectively, for 3024 ACBCPW samples having different electrical parameters and physical dimensions, compared with the results of respective quasi‐static analysis. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:211–216, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25666
Spectrum sensing cognitive‐wave‐radio for interference identification in wireless communications
Authors: Xu Yansheng , Aljerjawi M. , Nerguizian C. , Bosisio R. G. 
Published: November 2010

AbstractPhysical layer of cognitive‐wave‐radio receiver is investigated to identify interference signals, by spectrum sensing, in the presence of received QPSK data at 20 Mbps. The investigated cognitive‐wave‐radio receiver structure is based on existing wave radio physical layer (six‐port receiver interferometer) adapted for the receiver data active cancellation. For active cancellation of the received digital data, four outputs of the standard wave radio receiver are used in conjunction with three “single pole double throw” switches providing a single output of the “zero state time interval” for spectrum sensing of the interference signal. Two interference signals were tested: a 7‐dBm amplitude modulated interference and a wide band white noise with 0.01 mW/MHz. The microwave carrier of the QPSK signal is set at an amplitude of 16 dBm and a carrier frequency of 3.5 GHz. Once the interference signal spectrum is identified, the QPSK data are transmitted through the available channel. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:195–200, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25670
Planar triangular monopole antenna with multioctave bandwidth
Authors: Naser‐Moghadasi M. , Dadashzadeh G.R. , Abdollahvand M. , Zehforoosh Y. , Virdee B. S. 
Published: November 2010

AbstractThis article presents the results of a novel triangular monopole antenna that exhibits multioctave performance. This modification significantly improves the antenna's impedance bandwidth by 167% over an ultrawideband frequency. The antenna's simulated return‐loss and radiation patterns show very good correlation with the fabricated antenna's measured results. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:10–14, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25673
Multioctave microstrip‐to‐coplanar waveguide vertical transition
Authors: Abbosh A. M. 
Published: November 2010

AbstractA vialess vertical microstrip‐to‐coplanar waveguide (CPW) transition that covers a multioctave bandwidth is proposed. The proposed transition utilizes the magnetic coupling in a pair of mcirostrip‐to‐slotline transitions derived from the microstrip/CPW structure. The presented device is designed following simple design guidelines. The simulated and measured results show that the proposed transition can achieve a six‐octave bandwidth. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:187–189, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25675
Wideband bandpass filter using microstrip ring
Authors: Jung Dong‐Jin , Lee Jung‐Kyu , Chang Kai 
Published: November 2010

AbstractA simple design for a wideband bandpass filter is presented.A compact filter structure is achieved by placing a microstrip ring between two parallel coupling gaps. 3D electromagnetic simulation and measurement of the proposed filter validate its wideband characteristics. The proposed filter exhibits good insertion loss <1.2 dB and group delay variation <0.2 ns. Both simulated and measured results show good agreement. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:154–155, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25678
Demodulation of the FBG temperature sensor with the tunable twin‐core fiber
Authors: Zou Yi , Dong Xiaopeng 
Published: November 2010

AbstractA novel linear edge filter based on a piece of tunable twin‐core fiber is proposed in this article.The transmission spectrum of the twin‐core fiber can be adjusted by pulling and twisting the twin‐core fiber to match the central wavelength of the Fiber Bragg Grating (FBG) used for the temperature sensor. The feasibility of the method is analyzed and demonstrated experimentally. This demodulation filter, which is based on the all‐fiber component, can be designed and adjusted according to the measurement sensitivity and range of FBG temperature sensor, so its characteristics of compact scheme and low cost would make this method more applicable. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:81–84, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25681
Melanoma Immunotherapy
Authors: Sivendran Shanthi , Glodny Bradley , Pan Michael , Merad Miriam , Saenger Yvonne 
Published: November 2010

AbstractMelanoma immunotherapy has been an area of intense research for decades, and this work is now yielding more tangible results for patients. Work has focused on 4 main areas: cytokine therapy, administration of immune‐modulating antibodies, adoptive T‐cell therapy, and vaccines. Cytokine therapy is an established treatment for advanced melanoma, and immune‐modulating antibodies have recently emerged as an exciting new area of drug development with efficacy now established in a phase III trial. Adoptive T‐cell therapy provides the proof of principle that T cells can attack and eliminate tumors. It has been challenging, however, to adapt this treatment for widespread use. Vaccines have generally yielded poor results, but intratumor pathogen‐based strategies have shown encouraging results in recent trials, perhaps due to stronger immune stimulation. A review of the field of melanoma immunotherapy is provided here, with emphasis on those agents that have reached clinical testing. Novel strategies to induce the immune system to attack melanomas are reviewed. In the future, it is envisioned that immunotherapy will have further application in combination with cytotoxic and targeted therapies. Mt Sinai J Med 77:620–642, 2010. © 2010 Mount Sinai School of Medicine
Advanced or Metastatic Pancreatic Cancer: Molecular Targeted Therapies
Authors: Bayraktar Soley , Rocha‐Lima Caio M. 
Published: November 2010

AbstractPatients with pancreatic cancer normally present with advanced disease that is lethal and notoriously difficult to treat. However, clinical developments over the past decade have been modest and advances are incremental at most. The core drug and the backbone of treatment in all settings of pancreatic adenocarcinoma—adjuvant, locally advanced, and metastatic—remains gemcitabine. The past decade of research focused initially on combining cytotoxic therapies with gemcitabine, and during that time a large number of studies have been published that aimed to target the molecular abnormalities implicated in pancreatic tumor growth, invasion, metastasis, angiogenesis, and resistance to apoptosis. This research is of particular importance, as data suggest that a large number of genetic alterations affect only a few major signaling pathways and processes involved in pancreatic tumorigenesis. Although laboratory results of targeted therapies have been impressive, until now only erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, has demonstrated marginal survival benefit in combination with gemcitabine in phase III clinical trials. Even though the failures of targeted therapies in the clinical setting are discouraging, it is reasonable to surmise that major progress will evolve as the molecular biology of pancreatic adenocarcinoma continues to be unraveled. This review describes some of the important developments and targeted agents for pancreatic cancer that have been tested in clinical trials. Mt Sinai J Med 77:606–619, 2010. © 2010 Mount Sinai School of Medicine
Genetics of Prostate Cancer Risk
Authors: Pomerantz Mark M. , Freedman Matthew L. 
Published: November 2010

Abstracttable 2 check and delteFor decades, physicians and researchers have recognized that family history is a significant risk factor for prostate cancer. The identification of the genes responsible for inherited risk, however, proved difficult. With the sequencing of the human genome and the completion of the initial phases of the International HapMap Project, the tools are available to scan the entire genome and find genetic markers for disease. Since 2006, more than 30 inherited variants strongly associated with prostate cancer have been reported. As the inherited component of the disease is revealed, efforts are ongoing to translate genetic findings into the clinic. Mt Sinai J Med 74:643–654, 2010. © 2010 Mount Sinai School of Medicine
Myeloproliferative Neoplasms: New Translational Therapies
Authors: Mascarenhas John , Hoffman Ronald 
Published: November 2010

AbstractThe myeloproliferative neoplasms represent a diverse group of hematologic malignancies that have been the subject of intense investigation over the last decade. Although clinical trials of the much anticipated small molecule inhibitors of Janus kinase 2 have shown that these experimental agents are successful in palliating many of the symptoms associated with the myeloproliferative neoplasms, they have not been reported to affect the disease initiating hematopoietic stem cell population or to alter the natural history of these disorders. Investigators remain optimistic that new information about the genetic and cellular origins gained from the efforts of numerous laboratories will ultimately translate in to the identification of new drug targets and more effective therapies. We hypothesize that ultimately, the use of combinations of drugs including chromatin modifying agents, immunomodulatory agents, anti‐apoptotic agents, cellular therapies and monoclonal antibodies will be required to effectively treat patients with myeloproliferative neoplasms. Mt Sinai J Med 77:667–683, 2010. © 2010 Mount Sinai School of Medicine
Lung Adenocarcinoma: Lessons in Translation from Bench to Bedside
Authors: Sangodkar Jaya , Katz Suzanna , Melville Heather , Narla Goutham 
Published: November 2010

AbstractLung cancer is currently the leading cause of cancer‐related death in the United States and worldwide, accounting for approximately a third of all cancer diagnoses and deaths. The American Cancer Society estimates 159,390 deaths from lung cancer in the United States for 2009 alone. The high mortality rate associated with lung cancer has prompted numerous exhaustive efforts to identify novel therapeutic targets and treatment modalities for this deadly disease. The characterization of signaling pathways underlying the development and progression of lung cancer, particularly lung adenocarcinoma, has been instrumental in developing novel therapeutic strategies to target aggressive metastatic disease. This paradigm is best illustrated in lung adenocarcinoma by recent studies of the epidermal growth factor receptor, which has been identified to be a critical diagnostic and therapeutic target. Our understanding of the central role of epidermal growth factor receptor in the development and progression of lung adenocarcinoma has led to the development of molecular agents against this key oncogene that have demonstrated significant clinical efficacy against the disease. Despite these successes, de novo or acquired resistance to these anti–epidermal growth factor receptor agents invariably develops, either through additional mutations in the epidermal growth factor receptor, or abnormal regulation of downstream signaling pathways. Thus, it is necessary to further investigate the molecular determinants of treatment resistance and to develop novel therapeutic strategies directed specifically against the molecular drivers of metastatic chemoresistant lung cancer. Given the heterogeneity and convergence of signaling pathways underlying both disease etiology and chemoresistance, future efforts to administer rationally designed agents against multiple molecular targets could serve to improve both first‐line and second‐line therapies for patients with lung adenocarcinoma. Mt Sinai J Med 77:597–605, 2010. © 2010 Mount Sinai School of Medicine
Bacterial overgrowth syndrome in myotonic muscular dystrophy is potentially treatable
Authors: Tarnopolsky Mark A. , Pearce Erin , Matteliano Andre , James Cindy , Armstrong David 
Published: November 2010

AbstractOver one third of patients with myotonic muscular dystrophy type 1 (DM1) have gastrointestinal complaints. The cause is multifactorial, and treatment options are limited. Twenty DM1 patients with gastrointestinal symptoms were screened over a 2‐year period using glucose breath hydrogen testing (GBHT) to evaluate the prevalence of small intestinal bacterial overgrowth (SIBO). Sixty‐five percent of patients had a positive GBHT, and diarrhea was the most common presenting symptom. Ciprofloxacin was the most common antibiotic used for treatment, and 70% of patients reported a good response to the initial course of treatment. Although the causes of gastrointestinal symptoms in patients with DM1 are multifactorial, small intestinal bacterial overgrowth is an important diagnostic consideration that is easily diagnosed using glucose breath hydrogen testing and often shows a good response to treatment with common antibiotics. Muscle Nerve 42: 853–855, 2010
A novel deletion mutation in GJB1 causes X‐linked Charcot–Marie–Tooth disease in a Han Chinese family
Authors: Lin Pengfei , Mao Fei , Liu Qiji , Yang Wanling , Shao Changshun , Yan Chuanzhu , Gong Yaoqin 
Published: November 2010

AbstractX‐linked Charcot–Marie–Tooth disease CMT (CMTX) is predominantly caused by mutations in the GJB1 gene that encode connexin32. We describe the clinical findings and the identification of a novel mutation in GJB1 in a large Han Chinese family with CMTX. Linkage to GJB1 was determined by genotyping five polymorphic markers flanking GJB1. Sequence alterations were determined by directly sequencing the coding region of the GJB1 gene. The affected members have variable clinical manifestations. Linkage analysis confirmed the cosegregation of the disease with the GJB1 locus. Sequencing of the GJB1 gene revealed a 1‐basepair deletion (c.110delT) in the coding region. The frameshift begins at amino acid 37 and generates a premature stop codon at position 83. The shortened peptide is unlikely to be functional, as it lacks most of the functional domains. The CMTX in this family is caused by a novel loss of function mutation. Muscle Nerve 42: 922–926, 2010
Validity and reliability of the purdue pegboard test in carpal tunnel syndrome
Authors: Amirjani Nasim , Ashworth Nigel L. , Olson Jaret L. , Morhart Michael , Chan K. Ming 
Published: November 2010

AbstractThere is a paucity of validated tests to quantify hand function impairment due to carpal tunnel syndrome (CTS). The aim of this study was to test the validity and reliability of the Purdue Pegboard Test (PPT) in CTS patients. We compared 190 CTS patients with 122 healthy, age‐matched controls. CTS severity was determined based on electrophysiologic parameters and the Levine Self‐Assessment Questionnaire. The time to complete the PPT and the test–retest reliability were tested. The test–retest reliability was high with an intraclass correlation coefficient of 0.91. Compared to healthy controls, the CTS patients were significantly slower. Although the functional performance generally declined with increasing severity of electrophysiologic abnormalities, the correlation between hand function decline and symptom severity in the young and middle‐aged groups was low. We conclude that the PPT is a valid and reliable tool to quantify functional impairment caused by CTS. It can be a useful outcome measure in young and middle‐aged patients. Muscle Nerve , 2011
Continuous endurance‐type exercise training does not modulate satellite cell content in obese type 2 diabetes patients
Authors: Snijders Tim , Verdijk Lex B. , Hansen Dominique , Dendale Paul , van Loon Luc J.C. 
Published: November 2010

AbstractEndurance‐type exercise training represents a cornerstone in type 2 diabetes treatment. However, the effects of prolonged continuous, endurance‐type exercise on muscle fiber characteristics remain equivocal. Fifteen obese male type 2 diabetes patients (61 ± 6 years) participated in a 6‐month continuous, endurance‐type exercise program. Muscle biopsies were collected before, and after 2 and 6 months of intervention. Muscle fiber type–specific composition, size, and satellite cell (SC) and myonuclear content were determined by immunohistochemistry. Although continuous endurance‐type exercise training lowered total body weight and reduced fat mass, no changes were observed in leg lean mass. At baseline, SC content was significantly lower in type II compared with type I muscle fibers. No change in SC content was observed after exercise training. Continuous endurance‐type exercise training lowers fat mass, but it does not increase leg lean mass and/or modulate muscle fiber characteristics in type 2 diabetes patients. Muscle Nerve, 2011