bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing nurse led innovations
Authors: Verma Rupa , Domingo Nancy P 
Published: June 2024

To innovate is to bring forward positive change for a population of people who are affected by a pervasive unmet need. In nursing and healthcare, new inventions must address how to advance quality issues. These advancements can be through one or further of the six disciplines of quality (e.g., safe, effective, efficient, indifferent, timely, and patient- centred). Nursing history is rich with invention sweats to advance the profession. Nursing has recently endured a new regeneration of focus on invention through academics, practice, disquisition, and education. Nursing must continue to evolve and meet the contemporary conditions of our peers and the people which we serve. Embracing the power of invention as a profession can help us address the multitudinous pervasive unmet nursing and healthcare needs across the globe.Innovation is “The design, invention, development, and/ or perpetration of new or altered products, services, systems, organizational structures, or business models for the purpose of creating new value for guests and fiscal returns for the establishment ”. The Advisory Committee on Measuring Innovation in the 21st Century Economy, 2008, pg. i).
RELAÇÕES DE PODER EM NARRATIVAS VIRTUAIS PRODUZIDAS POR JOVENS:
Authors: Bianchi Pamela Cristina , Autiero da Costa Gabriela Helena 
Published: June 2024

Temas relativos ao ciberespaço vêm ganhando mais relevância na contemporaneidade. A juventude aparece como protagonista desse processo impulsionando e produzindo novas manifestações culturais neste universo. Dentre elas, destacam-se as fanfictions, narrativas construídas virtualmente por e para fãs. O estudo teve como objetivo identificar, sob a perspectiva das Epistemologias do Sul, como o colonialismo, o patriarcado e o capitalismo se manifestam nas fanfictions. Realizou-se uma pesquisa documental qualitativa, com leitura e análise de três narrativas publicadas em plataformas online. Notou-se a presença das três estruturas de poder: destaque ao patriarcado, expresso em cenas de objetificação e violências contra a mulher; o colonialismo, visualizado pela presença de apenas personagens brancos; e o capitalismo, através do protagonismo do estilo de vida das classes sociais dominantes. Os resultados apontam que as produções juvenis têm sido espaços de reprodução de relações de poder dominantes no cenário atual.
Política linguística como política de domínio territorial
Authors: Colaça Joyce Palha , Mariani Bethania 
Published: June 2024

No artigo em tela, fazemos um percurso de análise sobre o National Security Education Program, um programa de Educação mantido pelo Departamento de Defesa norte-americano, cujo objetivo é a aprendizagem do que denominam como línguas críticas em relação a áreas críticas. Tomamos como base para nossa discussão os estudos do campo do discurso no seu encontro com a História das Ideias Linguísticas, que pensa as línguas em sua historicidade como “corpo simbólico” e as políticas de línguas, ou seja, as tensões que percorrem os sentidos políticos para as línguas nas lutas sociais (ORLANDI, 2007). Como corpus de análise, nos detivemos aos textos descritos na página web do Programa, considerando tanto os aspectos da constituição de sua história, objetivos e alcance, como as tabelas descritivas nas quais demonstram as áreas e as línguas críticas que são prioritárias para o governo norte-americano. Em nossa análise, foi possível discutir o processo de produção de sentidos que engendra como evidência, nos dias atuais, uma certa relação entre línguas e territórios. Em nosso gesto de análise, como modo de trabalhar com o dito e o não dito constitutivo do processo de significação desse programa, traçamos um percurso que passa pela historicidade das dominações em relação à aprendizagem de línguas como estratégia de guerra, uma estratégia que ultrapassa o campo bélico.
Testosterone
Authors: Arcand Michel A. , Poulin Dominique , Testa Edward J. , Lemme Nicholas J. 
Published: June 2024

» Testosterone replacement treatment (TRT) and anabolic androgenic steroid (AAS) use is common and possibly increasing.» Diagnosing and treating hypogonadism in men is controversial.» Hypogonadism and the use of AASs seem to have a detrimental effect on the musculoskeletal system. The current literature on TRT and the musculoskeletal system shows an increased risk of tendon injury.» There may be a role for testosterone supplementation in the postoperative period.
A histological study of the black-winged kite's retina (Elanus caeruleus, Desfontaines, 1789)
Authors: Abid Shaimaa Awad , Haba Mukhtar Khamis 
Published: June 2024

أظهرت الدراسة أن شبكية عين الطائرالجارح النهاري الغازي Elanus caeruleus ، هي لاوعائية وتزود بالتغذية والأكسجين عن طريق المشيمية وممشط العين. تتكون شبكية العين من طبقتين: الطبقة الخارجية تسمى الظهارية المخضبة ، والطبقة الداخلية هي الطبقة العصبية. تتكون الطبقة العصبية من تسع طبقات: طبقة الخلايا البصرية ، الغشاء المحدد الخارجي ، الطبقة النووية الخارجية ، الطبقة الضفيرية الخارجية ، الطبقة النووية الداخلية ، الطبقة الضفيرية الداخلية ، طبقة الخلايا العقدية ، طبقة الألياف العصبية ، الغشاء المحدد الداخلي. تتكون طبقة الخلية البصرية من مخاريط مزدوجة ، ومخاريط مفردة وقضبان ، وتكون المخاريط أكثر من القضبان. أن الطبقة النووية الخارجية تحتوي على خلايا بصرية متراصة. تتميز الطبقة النووية الداخلية بأن خلاياها متنوعة ومتراصة بشكل كبير وتتألف من خلايا ثنائية القطب، والخلايا الافقية، و الخلايا عديمة البروزات الطويلة، وخلايا مولر. وتكون الطبقة الضفيرية الداخلية أكثر سمكًا من الطبقة الضفيرية الخارجية. تحتوي شبكية العين على الحفيرة العميقة والحفيرة الضحلة. تتميز الحفيرة العميقة بجدران محدبة حول النقرة العميقة والواسعة. تحتوي النقرة في الحفيرة العميقة على مخاريط رفيعة فقط ، وعدد قليل من الخلايا في الطبقة النووية الداخلية ، وعدم وجود الخلايا العقدية. تحتوي الحفيرة الضحلة على جميع طبقات الشبكية الموجودة في النقرة. ولكن ان صفوف الطبقة الشبكية الداخلية اقل عدد مما كانت عليه في المنطقة القريبة من الحفيرة.
DNA barcoding of seven cyprinid fish species in the Iraqi Inland waters using mitochondrial COI gene sequence
Authors: Ziyadi Mustafa Sami Faddagh 
Published: June 2024

إن عائلة Cyprinidae هي أكبر عائلة سمكية في المياه الداخلية العراقية. تاريخيا وصفت أنواع الأسماك الشبوطيات بواسطة القياسات المظهرية التقليدية. تعتبر أنواع أسماك عائلة Cyprinidae في العراق مهمة من النواحي البيئية والاقتصادية. في حين أن التشابه المورفولوجي بين أنواع أسماك الشبوطيات جعل تحديد الأنواع ليس أمرا سهلا. اختيرت شفرة الحامض النووي لتأكيد التصنيف وايضاح التنوع الجيني بين الأنواع المتشابهة العائدة للجنس نفسه. جمعت سبعة أنواع من أسماك الشبوطيات Luciobarbus barbulus، L. xanthopterus، L. kersin، L. esocinus، Arabibarbus grypus، Cyprinus carpio، و Acanthobrama marmid من نهر شط العرب والأهوار وخزان سد الموصل. تم تضخيم جين الميتوكوندريا Oxidase C Cytochrome للجين المستهدف وتحليل التتابع النيوكليوتيدي. اختيرت بادئات مخصصة لهذا الغرض. أستخدم برنامج Chromas لمعالجة نتائج التتابع النيوكليوتيدي. وأظهرت النتيجة أن التتابع النيوكليوتيدي تراوح بين 600-657 زوج قاعدي. في حين كشفت الشجرة الوراثية neighbor joining tree المتحصلة من موقع Clustal Omega عن أنواع Luciobarbus الأربعة التي تتجمع في فرعين مركزيين، بينما تباعدت الأنواع الثلاثة الأخرى. وتمت مقارنة توزيع النيوكليوتيدات إحصائيا لأنواع الأسماك المدروسة باستخدام برنامج CLC bio . أثبتت نتائج ترميز الحامض النووي باستخدام تسلسل الجينات COI وجود أربعة أنواع من أسماك Luciobarbus المستقلة. أثبتت الدراسة إن أستخدام جين COI كشفرة وراثية للحامض النووي ناجحا ودقيقا في تحديد الأنواع. أودعت التتابعات في البنك الجيني تحت رموز OM669701 و OM669699 و OM669702 و OM669705 و OM669703 وOM669700 و OM669704. إن هذه الدراسة هي نقطة الانطلاق لمشروع ترميز الحامض النووي لجميع الشفرات الوراثية للأنواع السمكية في المياه الداخلية العراقية. بالإضافة إلى ذلك، ستكون نتائج الدراسة مفيدةً جداً في برنامج الحفاظ على الأنواع المحلية في المياه الداخلية العراقية.
Personalized evaluation of the passive myocardium in ischemic cardiomyopathy via computational modeling using Bayesian optimization
Authors: Torbati Saeed , Daneshmehr Alireza , Pouraliakbar Hamidreza , Asgharian Masoud , Tafti Seyed Hossein Ahmadi , Shum-Tim Dominique , Heidari Alireza 
Published: June 2024

Abstract

Biomechanics-based patient-specific modeling is a promising approach that has proved invaluable for its clinical potential to assess the adversities caused by ischemic heart disease (IHD). In the present study, we propose a framework to find the passive material properties of the myocardium and the unloaded shape of cardiac ventricles simultaneously in patients diagnosed with ischemic cardiomyopathy (ICM). This was achieved by minimizing the difference between the simulated and target end-diastolic pressure-volume relationships (EDPVRs) using black-box Bayesian optimization, based on the finite element analysis (FEA). End-diastolic (ED) biventricular geometry and the location of the ischemia were determined from cardiac magnetic resonance (CMR) imaging. We employed our pipeline to model the cardiac ventricles of three patients aged between 57 and 66 years, with and without the inclusion of valves. An excellent agreement between the simulated and target EDPVRs has been reached. Our results revealed that the incorporation of valvular springs typically leads to lower hyperelastic parameters for both healthy and ischemic myocardium, as well as a higher fiber Green strain in the viable regions compared to models without valvular stiffness. Furthermore, the addition of valve-related effects did not result in significant changes in myofiber stress after optimization. We concluded that more accurate results could be obtained when cardiac valves were considered in modeling ventricles. The present novel and practical methodology paves the way for developing digital twins of ischemic cardiac ventricles, providing a non-invasive assessment for designing optimal personalized therapies in precision medicine.
State-behaviour feedbacks between boldness and food intake shape escape responses in fish
Authors: Planas-Sitjà Isaac , Ioannou Christos 
Published: June 2024

Abstract

Consistent differences in intrinsic state, amplified through state-dependent behaviour, could explain the ubiquity of animal personality variation. Boldness is often positively associated with a high metabolism and food intake. Even though a high food consumption is known to compromise oxygen-demanding activities, the influence of food intake on the anti-predator escape responses has rarely been considered. By conducting experiments with three-spined sticklebacks (Gasterosteus aculeatus) in a setup with real-time tracking and a decoy heron predator, we show that bolder fish benefited from a higher food intake than shy fish, and reacted faster to a predator attack when food intake was the same before being attacked. However, a higher food intake slowed down the escape reaction of fish. These results shine light on how the fitness of shy and bold strategies could be balanced in the wild: the faster reaction of bold fish is impaired by their higher food consumption.
Maternal Stress: Not Just a Mental Illness, but Also a Health Hazard
Authors: Dušová Bohdana , Chromá Jana , Greplová Kateřina , Poláková Hana 
Published: June 2024

Abstract

Objective
Postpartum stress is a common phenomenon experienced by many mothers. It can manifest itself in various symptoms such as fatigue, irritability, insomnia, anxiety, depression and fear. In severe cases, it can lead to the development of postnatal psychosis. The objective of this study is to identify and assess the subjective perception of postpartum maternal stress in relation to selected socio-demographic characteristics and to determine the association between subjectively perceived maternal postpartum stress and midwifery care.
Methodology:
The study population consisted of 200 respondents who had given birth to one healthy child and their postpartum period was in the range of six months. The study was conducted in a pediatrician (referred to as a ‘general practitioner for children and adolescents’ in the Czech Republic) outpatient offices, May 2022 to January 2023. The survey utilized the standardized Maternal Postpartum Stress Scale (MPSS) questionnaire, which was supplemented with socio-demographic data and information on whether midwifery care had been provided.
Results
The study participants had an overall mean score of postpartum stress 32.7. The stress scores for each subscale were as follows: 15 for personal needs and fatigue of the mother, 9.9 for infant nurturing, and 7.8 for body changes and sexuality. The study found a statistically significant relationship between the number of births and body changes and sexuality (p = 0.0097). Statistical significance level 5%. However, no statistically significant effects of sociodemographic parameters or midwifery care were found in the study population.
Conclusion
In the study population, overall postpartum stress was mild to moderate. Sociodemographic parameters and midwife care did not have a statistically significant effect on subjective perception of maternal postpartum stress. Research shows that mothers who have had more than one birth are more prone to experiencing stress in terms of body changes and sexuality after childbirth. It is therefore important to give these mothers extra attention and offer them support and help to cope with these challenging changes
Are laterality effects present in novel object responses of calves?
Authors: Zhang Chenyu , Kindell Molly , Meagher Rebecca 
Published: June 2024

Abstract

Many animals exhibit preferential viewing of fear-inducing stimuli with their left eyes, reflecting cerebral lateralisation in emotion processing. In novel object tests, often used to assess fear, spatial positioning of objects relative to the animal can vary. This study aimed to investigate visual lateralisation in fear processing in novel object tests, evaluate its effectiveness as an indicator of fear, and examine how initial monocular presentation of fear-inducing stimuli impacts fear responses and their reliability. Thirty-six calves underwent a novel object test at six weeks of age and a second at seven weeks of age using a different object, with behavioural responses towards the novel objects recorded. There was no correlation in latency to first contact with novel objects between tests. Proportion of time viewing novel objects with the left eye did not significantly differ from the right eye, nor did it correlate with latency to first contact with novel objects. The probability of contact with novel objects and latency to first contact with novel objects did not differ based on initial eye contact with novel objects. Overall, fear responses in calves during repeated novel object tests were inconsistent, but this inconsistency could not be explained by novel objects being randomly presented to calves’ different visual fields, which suggests potential absence of cerebral lateralisation in fear processing. Thus, laterality of visual response may not reliably indicate fear in calves at this age.
Novel Biosynthesis and Evaluation Cytotoxic Effect of Tellurium Nano-Particle on Breast Cancer Using Co-Culture of Spirulina and Lentinula Edodes
Authors: Reza Mahdieh Ameri Shah , Rasouli Alireza , Movahhed Tahereh Komeili 
Published: June 2024

Abstract

Introduction
Bio-based nanoparticle production has been an alternative method for preparing nanoparticles for pharmaceutical and biomedical applications. This study aims to evaluate the production of tellurium nanoparticles (TeNPs) using the co-culture of algae and fungi and finally to investigate the cytotoxicity of nanoparticles on cancer cell lines MDA-MB-468 and healthy cell line HFF.
Methods
The production of TeNPs was done using the co-culture of algae and fungi. Using the Tyndall effect, FTIR, and FESEM, nanoparticles were evaluated. Finally, using the MTT assay, the toxicity of the nanoparticles produced on MDA-MB-468 and HFF was investigated.
Results
Data showed that it is possible to produce TeNPs using the co-cultivation of algae and fungi. Also, the produced nanoparticles had a size between 20 and 30 nm. Examining the cytotoxicity effects of the created nanoparticle showed that this nanoparticle has an inhibitory effect on cancer cells, while it does not affect healthy cells.
Conclusion
In this study, biosynthesis of TeNPs using co-culture was performed for the first time. The data showed that it is possible to use the co-culture of algae and fungi to produce TeNPs that can inhibit the growth of human breast cancer cells.
Prevalence, radio-clinical patterns and factors associated with pulmonary tuberculosis among children with severe acute malnutrition: A crossectional study in Uganda
Authors: Asiimwe Oliver , Ndezi Grace , Nduwimana Martin , Namukasa Faith , Mutisya Charles Mwendwa , Abdirahman Salad Hassan , Abdifatah Ali Muhuyadin haji , Abdirizak Omar Mohamed , Amatarahman Said Ibrahim , Muhumuza Joshua 
Published: June 2024

Abstract

Background
Although treatable, pulmonary tuberculosis (PTB) has a significant morbidity and mortality. Children with malnutrition are immune compromised, which increases the morbidity and mortality of PTB. This study was done to determine the prevalence and factors associated with Tuberculosis among children aged 6 to 59 months admitted with severe acute malnutrition (SAM) at Jinja Regional Referral Hospital (JRRH).
Methods
This was a cross–sectional study among children aged 6-59 months with SAM at JRRH. History was taken and physical examination done. Gene Xpert was done for all participants, Lipoarabinomannan Antigen Assay for TB (TB-LAM) done for HIV positive children with CD4 below 200 and Chest X-ray for children who presented with cough and difficulty in breathing. Both the investigations and clinical findings were used to make a diagnosis of PTB. Using binary logistic regression in SPSS, the factors associated with Tuberculosis were determined. P value <0.05 was considered significant.
Results
Of the 137 children enrolled with SAM, majority were in the age groups of 6-11 and 12-23 months. Non-edematous malnutrition was the commonest 73(53.3%). Thirty-two children were diagnosed with TB with a prevalence of 23.4%. Of the 32 diagnosed with Tuberculosis, only 5 had a positive gene expert test, 2 had a positive urine TB LAM and the remaining 25 were diagnosed using the clinical criteria. The commonest symptoms among children diagnosed with TB were cough seen in 25/32 (78.1%) and fever in 24/32 (75%). The most common radiological findings comprised adenopathy (64.3%) and consolidations (49.7%). Coming from rural areas (aOR=1.205, 95%CI=1.067-1.360, P=0.003), being HIV positive (aOR=1.619, CI=1.114-2.354, P=0.012), thrombocytopenia (aOR=1.407, CI=1.069-1.853, P=0.015) and thrombocytosis (aOR=1.202, CI=1.047-1.379, P=0.009) were independently associated with presence of Tuberculosis.
Conclusion
The prevalence of tuberculosis in Severe Acute Malnutrition was high. Children with SAM should be routinely screened for TB. When resources are constrained, the iinvestigations for TB could be focused on those coming from rural areas, the HIV positive, those with thrombocytopenia and those with thrombocytosis.
the Interaction Proteome of Ribosomal 40S Components PNO1 and NOB1 Using TurboID Proximity Labeling Technology
Authors: Xu Xingyuan , Zheng Jiefu , Chen Wenli , Liao Jian-You , Zhu Shuang 
Published: June 2024

Abstract

Background
The ribosome assembly factors PNO1 and NOB1 play crucial roles in the maturation of the 40S ribosomal small subunit. TurboID is an efficient biotin ligase that can biotinylate proteins in proximity to the target protein and is widely used to study complex biological processes within cells.Here, we utilized this technology to investigate the complex interaction network of PNO1 and NOB1 within cells.
Results
Through immunofluorescence experiments, we found that PNO1 and NOB1 have different localizations within cells. By identifying the proximal proteins biotinylated by PNO1-TurboID and NOB1-TurboID, we discovered 871 proteins interacting with PNO1 and 1044 proteins interacting with NOB1, with 663 proteins overlapping. These results suggest that PNO1 and NOB1 are extensively involved in various biological processes within the cell. Furthermore, we found that PNO1 and NOB1 interact with translation-related proteins EIF4B and EIF4G2, indicating that they may participate in the mRNA translation process.
Conclusion
The interaction proteome results of PNO1 and NOB1 suggest that ribosome assembly factors are not only involved in ribosome biogenesis but also couple with multiple biological processes within the cell, such as mRNA translation. This provides a foundation for understanding the complex biological processes within the cell.
solar: A solar thermal power plant simulator for blackboxoptimization benchmarking
Authors: Andres-Thio Nicolau , Audet Charles , Diago Miguel , Gheribi Aimen , Digabel Sébastien Le , Lebeuf Xavier , Garneau Mathieu Lemyre , Tribes Christophe 
Published: June 2024

Abstract

This work introduces solar, a collection of ten optimization problem instances for benchmarking blackbox optimization solvers.The instances present different design aspects of a concentrated solar power plant simulated by blackbox numerical models.The type of variables (discrete or continuous), dimensionality, and number and types of constraints (including hidden constraints) differ across instances.Some are deterministic, others are stochastic with possibilities to execute several replications to control stochasticity. Most instances offer variable fidelity surrogates, two are biobjective and one is unconstrained.The solar plant model takes into account various subsystems: a heliostats field, a central cavity receiver (the receiver), a molten salt thermal energy storage, a steam generator and an idealized power block. Several numerical methods are implemented throughout the solar code and most of the executions are time-consuming. Great care was applied to guarantee reproducibility across platforms.The solar tool encompasses most of the characteristics that can be found in industrial and real-life blackbox optimization problems, all in an open-source and stand-alone code.
AMS subject classifications: 90-04, 90-10, 90C56.
Enhancing Genetic Prompt Search Using Language Model Probability Exploitation
Authors: Song Zichen , Huang Sitan 
Published: June 2024

Abstract

In the application of large pre-trained language models (PLMs), prompt-tuning techniques have demonstrated notable effectiveness in low-resource settings, such as learning from a small number of samples. Concurrently, derivative-free optimization (DFO) techniques enable prompt tuning on black-box PLMs, enhancing adaptation to specific downstream tasks. However, current DFO-based prompt-tuning methods typically rely on certain prerequisites, such as requiring additional APIs from PLMs to inject continuous prompts as hidden states or embedding vectors, or necessitating well-designed discrete manual prompts as initial states for the algorithm. To overcome these limitations and make DFO-based prompt tuning more universally applicable, we propose a novel genetic algorithm (GA). This algorithm starts with a blank prompt and drives the evolution of the prompt by leveraging prediction probabilities guided by a small-sample training set, thus selecting appropriate tokens. Experiments across multiple diverse benchmark datasets have shown that this unconditional approach significantly outperforms existing prerequisite-dependent DFO methods, such as black-box tuning, genetic prompt search, and gradient-free imperative prompt search.