bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pramipexole in the treatment of Restless Legs Syndrome
Authors: Schapira Anthony HV 
Published: July 2010

AbstractRestless Legs Syndrome (RLS) was first described by Sir Thomas Willis, an English physician, in London in 1672, but has only recently become recognised as a specific disease entity. Although epidemiological studies suggest that it is one of the most common neurological disorders, awareness of the syndrome remains relatively low among both patients and physicians. As a result, diagnosis can often be delayed, or even missed. What is apparent is that RLS can cause substantial morbidity and that, with symptomatic relief now available, there is an increased need to identify and diagnose those patients who require therapy. This article considers and summarises the evidence for treatment with pramipexole (Mirapexin), recently licensed for use in RLS. Copyright © 2007 Wiley Interface Ltd
Hemerobiiden aus Bulgarien (Neuroptera)
Authors: Popov Alexi 
Published: July 2010

Hemerobiidae from Bulgaria (Neuroptera)New localities for the total of 28 species of Hemerobiidae occurring in Bulgaria are reported. Out of these Hemerobius zernyi is new for the fauna of continental Europe and Wesmaelius fassnidgei, Wesmaelius mortoni, Hemerobius atrifrons, Hemerobius schedli, Hemerobius marginatus, Psectra diptera, and Sympherobius klapaleki are new for the Balkan Peninsula. The finds in Bulgaria offer a major contribution to our knowledge on the distribution of Wesmaelius fassnidgei, Hemerobius schedli, and Hemerobius zernyi as well as of Hemerobius atrifrons and Sympherobius klapaleki; 8 other species have a range further south. Species of northern origin prevail in Bulgarian fauna (71%). Zoogeographically they are oreotundral (with alpine, oreal origin) – 1 species and arboreal – the remaining species, namely: Holarctic – 3, Siberian – 11, Siberian‐Mediterranean – 2, Middle European – 3, Holomediterranean – 7 and Pontomediterranean – 1.
Nonisothermal cocuring behavior and kinetics of epoxy resin/3‐glycidyloxypropyl‐POSS with MeTHPA
Authors: Gao Jungang , Kong Dejuan , Li Shurong 
Published: July 2010

Abstract3‐Glycidyloxypropyl‐polyhedral oligomeric silsesquioxanes (G‐POSS) was prepared from 3‐glycidyloxypropyl‐trimethoxysilane (GTMS) by hydrolytic condensation. The cocuring behavior and kinetics of G‐POSS with bisphenol‐A epoxy resin (BPAER) using 3‐methyl‐tetrahydrophthalic anhydride (MeTHPA) as curing agent were investigated by nonisothermal differential scanning calorimetry (DSC) and torsional braid analysis (TBA). The face distribution of silicon in the cured products was characterized by energy dispersive X‐ray spectrometry (EDS). The results show that the compatibility of G‐POSS with BPAER is very well and can cocure. The curing mechanism was proposed. The relationship of Ea and conversion α can be obtained by the isoconversional method of Kissinger. These curing reactions can be described by the Šesták–Berggren (S–B) equation and can be depicted by the following equation:
$ \font\abc=cmmib10\def\bi#1{\hbox{\abc #1}}{\bi d\alpha \over \bi dt} {=} A\ {\bf exp} (-{E_a \over RT}) {{\alpha}}^m ({\bf 1}-a)^n $. TBA analysis indicated that Tg was decreased when the contents of G‐POSS is over to 30 wt%. POLYM. COMPOS., 2010. © 2009 Society of Plastics Engineers
Microstructure and field mapping of AlInN‐based heterostructures and devices
Authors: Zhou Lin , Cullen David A , McCartney Martha R. , Leach Jacob H. , Fan Qian , Morkoç Hadis , Smith David J. 
Published: July 2010

AbstractThe microstructure, composition and electrostatic fields of near‐lattice‐matched Al1‐xInxN/AlN/GaN heterostructures and devices have been characterized using a variety of electron microscopy techniques. A thin parastic Ga‐rich layer was often observed immediately above the AlN spacer and was attributed to GaN nucleation during specimen cooling. Mapping of electrostatic potential profiles across a GaN/Al0.85In0.15N/AlN/ GaN heterostructure using off‐axis electron holography showed polarization‐induced fields of 7.5MV/cm within the AlN layer, and 2.2MV/cm within the Ga‐rich layer. A two‐dimensional electron gas with a density of ∼9.8×1012 cm–2 was observed in the underlying GaN layer located very close to the AlN/GaN interface. Contact inclusions were observed extending into the AlInN and GaN layers along mixed‐type threading dislocations under the source and drain regions of HFET devices. The density and size of the contact inclusions was determined by the annealing temperature (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Content distribution in trail-aware environments
Authors: Silva Jader M. , Rosa João H. , Barbosa Jorge L. V. , Barbosa Débora N. F. , Palazzo Luiz A. M. 
Published: July 2010

Abstract
In mobile computing environments, the tracking of users allows applications to adapt to the contexts visited by users (Context Awareness). In recent years, the use of context information and users’ profiles has been considered an opportunity for context-aware content management. The improvement and the wide adoption of location systems are stimulating the tracking of users, allowing the use of Trails. A trail is the history of the contexts visited by a user during a period. This article proposes a model for trails management and its application in the content management. In this text, we consider that Trail-Aware is an evolution of the simple use of contexts and profiles. The text presents a prototype and its application in an educational environment for distribution of learning objects using trail-aware.
High frequency of childhood ADHD history in women with fibromyalgia
Authors: Reyero F. , Ponce G. , Rodriguez-Jimenez R. , Fernandez-Dapica P. , Taboada D. , Martin V. , Navio M. , Jimenez-Arriero M.A. , Hoenicka J. , Palomo T. 
Published: July 2010

AbstractFibromyalgia and ADHD share some clinical features, and a reduced dopamine function has been proposed for both disorders. Here we found, in a large sample of fibromyalgia female patients, a higher frequency of childhood ADHD antecedent when compared with healthy women. Our data suggest that Fibromyalgia and ADHD have some common etiopathological mechanism.
Assessing the infrequent oral supplementation of olanzapine long-acting injection in the treatment of schizophrenia
Authors: Ascher-Svanum H. , Peng X. , Montgomery W. , Faries D.E. , Lawson A.H. , Witte M.M. , Novick D. , Jemiai N. , Perrin E. , McDonnell D.P. 
Published: July 2010

AbstractObjectiveAdding another antipsychotic to a treatment regimen was previously used in evaluating the medication's efficacy. Supplementation of depot antipsychotics with oral antipsychotics is particularly meaningful because depot formulations are typically chosen for patients struggling with adherence to oral antipsychotics. This post-hoc analysis assessed supplementation of olanzapine long-acting injection (olanzapine-LAI) with oral olanzapine.Subjects and methodsWe used 12 months of data from an open-label, single-arm extension study of patients with schizophrenia or schizoaffective disorder (N = 931) treated with olanzapine-LAI. The prevalence, duration, time to first supplementation, and best predictors of oral supplementation were assessed.ResultsOral supplementation occurred in 21% of patients for a median of 31 days with mean modal dose of 10.8 mg/day. Mean time to first supplementation was shorter for patients who were at least moderately ill at baseline compared to less ill patients (47 vs. 97 days, p < 0.001). Best predictors of oral supplementation included a more severe illness profile at baseline, lower olanzapine-LAI dose prior to oral supplementation, supervised living arrangements, and being African-American.ConclusionSupplementation of olanzapine-LAI appears to be infrequent, of relatively short duration, and reserved for more severely ill patients who may require a targeted rescue medication due to signs of impending relapse.
A prospective, observational study of the safety and effectiveness of intramuscular psychotropic treatment in acutely agitated patients with schizophrenia and bipolar mania
Authors: Perrin E. , Anand E. , Dyachkova Y. , Wagner T. , Frediani S. , Ballerini A. ,   the OBS-IM investigators group
Published: July 2010

AbstractThis naturalistic, observational pan-European study assessed the safety and early effectiveness of intramuscular (IM) psychotropic treatments in patients with acute agitation suffering from schizophrenia or bipolar mania. One thousand nine hundred and forty of 1945 patients completed the 24-hour observation period after initial IM treatment. Patients from 12 European countries were included (mean age 39 years; 58% male, 66% schizophrenia). IM treatment was at the physician's discretion. The primary objective was to describe the acute tolerability of IM psychotropic therapies in clinical practice, with particular emphasis on EPS. At baseline, 68% of the patients received IM monotherapy, with IM olanzapine most commonly prescribed (36%). During the first 24hours, 190 (9.8%) patients experienced EPS. The occurrence of EPS was statistically significantly lower in patients treated with IM olanzapine compared to those treated with other IM psychotropic medications (mainly typical antipsychotics and benzodiazepines): acute dystonia: 1.1%, 95% CI 0.5–2.3 and 2.9%, CI 2.0–4.0; akathisia: 2.3%, CI 1.3–3.7 and 5.5%, CI 4.3–6.9; Parkinsonism: 2.9%, CI 1.8–4.4 and 7.8%, CI 6.4–9.4, respectively. Anticholinergic treatment was given to 12% IM olanzapine versus 31% non-olanzapine treated patients. Acute agitation after 24hours was reduced by 1.68 (95% CI 1.46–1.91) points on the Clinical Global Impression of Severity (CGI-S) in IM olanzapine patients and 1.51 (95% CI 1.30–1.73) points in non-olanzapine patients. Additional psychotropic medication was required for 90% of the patients during the first 24hours of treatment. Results provide naturalistic evidence for low EPS rates and improvement of agitation with IM psychotropic medications during acute states of patients suffering from acute mania or schizophrenia.
Firearm Suicides And Availability Of Firearms: The Swiss Experience
Authors: Ajdacic-Gross V. , Killias M. , Hepp U. , Haymoz S. , Bopp M. , Gutzwiller F. , Rössler W. 
Published: July 2010

AbstractThis study aimed to examine the association between the availability of firearms at home, and the proportion of firearm suicides in Switzerland in an ecological analysis. The data series were analysed by canton and yielded a fairly high correlation (Spearman's rho = 0.60). Thus, the association holds also at a sub-national level.
Correlations between sadness-induced cerebral activations and schizophrenia symptoms: An fMRI study of sex differences
Authors: Mendrek A. , Jiménez J.A. , Mancini-Marïe A. , Fahim C. , Stip E. 
Published: July 2010

AbstractBackgroundThe functional neuroimaging studies of emotion processing in schizophrenia have revealed variable results attributed partly to differential symptomatology and sex of tested patients. The aim of the present study was to investigate the relationship between cerebral activations during exposure to emotional material and schizophrenia symptoms in men versus women.MethodFifteen men and 10 women with schizophrenia, equivalent in terms of age, medication and experienced symptomatology, underwent functional MRI during viewing sad and neutral film excerpts. Data were analyzed using Statistical Parametric Mapping Software (SPM2).ResultsAcross all the patients there was a significant inverse relationship between negative symptoms and activations in the right prefrontal cortex during processing of sad versus neutral stimuli. In men, activations during sad versus neutral stimuli in the prefrontal, temporal and anterior cingulate cortex, as well as the caudate and cerebellum, were positively correlated with negative symptoms. In women, there were inverse correlations between positive symptoms and activations in the hippocampus, parietal and occipital cortex during the same condition.ConclusionPresent results confirmed association of prefrontal hypofunction with negative symptoms in schizophrenia. More interestingly, the results revealed a diametrically different pattern of symptom-correlated brain activity in men and women with schizophrenia, suggesting that the processing of sadness is mediated via neurophysiological mechanism related to negative symptoms in men and the mechanism related to positive symptoms in women.
Do they Actually Work Across Borders? Evaluation of two Measures of Psychological Distress as Screening Instruments in a Non Anglo-Saxon Country
Authors: Carrà G. , Sciarini P. , Segagni-Lusignani G. , Clerici M. , Montomoli C. , Kessler R.C. 
Published: July 2010

AbstractScreening scales can be useful in searching for common mental disorders in primary care and in tracking relevant prevalence and correlates in community surveys. However, it is important to document their validity, before using them. We developed Italian versions of the widely-used K10 and K6 screening scales following the WHO forward-translation and back-translation protocol. To evaluate their effectiveness as screens for DSM-IV 12-month mood or anxiety disorders and “serious mental illness” (SMI), the scales were validated in a two-stage clinical reappraisal survey. In the first-phase, the scales were administered to 605 people. In the second-phase, a sub-sample of 147 first-phase respondents over-sampling screened positives was administered the 12-month version of the Structured Clinical Interview for DSM-IV Axis I Disorders as a clinical gold standard. Performance of the scales in screening for chosen disorders was assessed by calculating area under the receiver operating characteristic curve and stratum-specific likelihood ratios. Both the K10 and K6 performed well in detecting DSM-IV mood disorders, anxiety disorders, and serious mental illness (SMI), with areas under the curve (AUCs) (95% CIs) between 0.82 (0.75–0.89) and 0.91 (0.85–0.96). The Italian versions of the K6 and K10 scales have good psychometric properties, making them attractive inexpensive screens for mood disorders, anxiety disorders, and SMI.
Brain imaging findings in children and adolescents with mental disorders: A cross-sectional review
Authors: Mana S. , Paillère Martinot M.-L. , Martinot J.-L. 
Published: July 2010

AbstractBackgroundWhile brain imaging studies of juvenile patients has expanded in recent years to investigate the cerebral neurophysiologic correlates of psychiatric disorders, this research field remains scarce. The aim of the present review was to cluster the main mental disorders according to the differential brain location of the imaging findings recently reported in children and adolescents reports. A second objective was to describe the worldwide distribution and the main directions of the recent magnetic resonance imaging (MRI) and positron tomography (PET) studies in these patients.MethodsA survey of 423 MRI and PET articles published between 2005 and 2008 was performed. A principal component analysis (PCA), then an activation likelihood estimate (ALE) meta-analysis, were applied on brain regional information retrieved from articles in order to cluster the various disorders with respect to the cerebral structures where alterations were reported. Furthermore, descriptive analysis characterized the literature production.ResultsTwo hundred and seventy-four articles involving children and adolescent patients were analyzed. Both the PCA and ALE methods clustered, three groups of diagnosed psychiatric disorders, according to the brain structural and functional locations: one group of affective disorders characterized by abnormalities of the frontal-limbic regions; a group of mental disorders with “cognition deficits” mainly related to cortex abnormalities; and one psychomotor condition associated with abnormalities in the basal ganglia. The descriptive analysis indicates a focus on attention deficit hyperactivity disorders and autism spectrum disorders, a general steady rise in the number of annual reports, and lead of US research.ConclusionThis cross-sectional review of child and adolescent mental disorders based on neuroimaging findings suggests overlaps of brain locations that allow to cluster the diagnosed disorders into three sets with respectively marked affective, cognitive, and psychomotor phenomenology. Furthermore, the brain imaging research effort was unequally distributed across disorders, and did not reflect their prevalence.
The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: Assessing courses, types and time stability of diagnostic classification
Authors: Möller H.J. , Jäger M. , Riedel M. , Obermeier M. , Strauss A. , Bottlender R. 
Published: July 2010

AbstractObjectiveIn the context of the development of DSM-V and ICD-11 it appears to be useful to get further data on the validity of the diagnostic differentiation between schizophrenic and affective disorders. This study investigated the relevance of the main diagnostic groups schizophrenia, schizoaffective psychosis and affective disorder in the context of different diagnostic systems (ICD-9, ICD-10, DSM –IV), assessing their time stability, long-term courses, types and functional outcome.MethodsA total of 323 first hospitalized inpatients of the Psychiatric Department of the University Munich were recruited at index time. The full follow-up evaluation including standardized assessment procedures could be performed in 197 patients.ResultsThe re-diagnosis of the patients’ disorders shows that with the transition from ICD-9 to ICD-10 or DSM-IV, the group of affective disorders increased numerically while the diagnostic groups of schizophrenia and schizoaffective disorders decreased in size. The structured clinical interview for DSM-IV (SCID) analysis showed that altogether ICD-10 and DSM-IV had a relatively high diagnostic stability. Of the patients with an ICD-10 diagnosis of schizophrenia, 57% had a chronic course; 61% of the patients with a DSM-IV diagnosis of schizophrenia. Patients with affective disorders, according either to ICD-10 or DSM-IV, had in more than 90% of the cases an episodic-remitting course. In terms of prediction of long-term outcome regarding the differentiation between chronic and non-chronic course, the ICD-10 diagnoses did give a slightly better predictive result than a dimensional approach based on the key psychopathological syndrome scores.ConclusionsThe differentiation between schizophrenic and affective disorders seems meaningful especially under predictive aspects. A dimensional syndromatological description does not exceed the predictive power of the investigated main diagnostic categories, but might increase the clinically relevant information.
A prospective longitudinal study of the impact of early postnatal vs. chronic maternal depressive symptoms on child development
Authors: Sutter-Dallay A.-L. , Murray L. , Dequae-Merchadou L. , Glatigny-Dallay E. , Bourgeois M.-L. , Verdoux H. 
Published: July 2010

AbstractBackgroundFew studies of the effects of postnatal depression on child development have considered the chronicity of depressive symptoms. We investigated whether early postnatal depressive symptoms (PNDS) predicted child developmental outcome independently of later maternal depressive symptoms.MethodsIn a prospective, longitudinal study, mothers and children were followed-up from birth to 2 years; repeated measures of PNDS were made using the Edinburgh Postnatal Depression Scale (EPDS); child development was assessed using the Bayley Scales II. Multilevel modelling techniques were used to examine the association between 6 week PNDS, and child development, taking subsequent depressive symptoms into account.ResultsChildren of mothers with 6 week PNDS were significantly more likely than children of non-symptomatic mothers to have poor cognitive outcome; however, this association was reduced to trend level when adjusted for later maternal depressive symptoms.ConclusionEffects of early PNDS on infant development may be partly explained by subsequent depressive symptoms.
Verbraucherschutz und die Optimierung der Strukturen des Gesundheitssystems
Authors: Kranich Christoph 
Published: July 2010

Einleitung
Wie steht Verbraucherschutz zum Gesundheitswesen und welche Rolle hat der Patient? Vom System der Fürsorge, das sich um kranke Menschen kümmert, wurde das Gesundheitswesen zum Supermarkt und der Kunde zum Objekt sich kreuzender Interessenströme mächtiger Akteure. Verbraucherschutz hat dieselben gegensätzlichen Ziele wie Prävention und Gesundheitsförderung: individuelle Hilfe, also die Arbeit mit Einzelnen, und systemische Unterstützung, bei der es um Hinweise auf strukturelle Mängel geht, die dringend abgestellt werden sollten.
A multiplier theorem for 𝐻¹(𝑅ⁿ)
Authors: Oberlin Daniel M. 
Published: July 2010

We prove the following theorem. Theorem. Let m be a nonnegative measurable function on

[
0
,
∞
)

[0,\infty )

. For

n
⩾
2

n \geqslant 2

, the two conditions below are equivalent: (a)

∫

R
n

|

f
^

(
x
)

|

m
(

|

x

|

)

d
x
>
∞

\smallint {\;_{{R^n}}}|\hat f(x)|m(|x|)\;dx > \infty

for each

f
∈

H
1

(

R
n

)

f \in {H^1}({R^n})

, (b)

sup
{

2

(
n
−
1
)
k

∫

2
k

2

k
+
1

m
(
r
)

d
r
:
−
∞
>
k
>
∞
}
>
∞

\sup \{ {2^{(n - 1)k}}\smallint _{{2^k}}^{{2^{k + 1}}}m(r)\;dr: - \infty > k > \infty \} > \infty

.
One-variable equational compactness in partially distributive semilattices with pseudocomplementation
Authors: Bulman-Fleming Sydney , Fleischer Isidore 
Published: July 2010

A universal algebra A is called one-variable equationally compact if every system of equations with constants in A involving a single variable x, every finite subsystem of which has a solution in A, has itself a solution in A. The one-variable equationally compact semilattices with pseudocomplementation

⟨
S
;
∧

,
∗

,
0
⟩

\langle S; \wedge {,^ \ast },0\rangle

which satisfy the partial distributive law

x
∧

(
y
∧
z

)
∗

=
(
x
∧

y
∗

)
∨
(
x
∧

z
∗

)

x \wedge {(y \wedge z)^ \ast } = (x \wedge {y^ \ast }) \vee (x \wedge {z^ \ast })

are characterized, and as a consequence we are able to describe the one-variable compact Stone semilattices. Similar considerations yield a characterization of the one-variable equationally compact Stone algebras, extending a well known result for distributive lattices.
Quotients of 𝐶^{𝑚}-{0} by diagonal 𝐶*-actions
Authors: Takijima Kunio 
Published: July 2010

Let

q
1

,
…
,

q
m

{q_1}, \ldots ,{q_m}

be positive integers with

(

q
1

,
…
,

q
m

)
=
1

({q_1}, \ldots ,{q_m}) = 1

and

ρ
:

C

∗

×

C

m

→

C

m

,
ρ
(
t
,

z
1

,
…
,

z
m

)
=
(

t

q
1

z
1

,
…
,

t

q
m

z
m

)

\rho :{{\mathbf {C}}^ \ast } \times {{\mathbf {C}}^m} \to {{\mathbf {C}}^m},\rho (t,{z_1}, \ldots ,{z_m}) = ({t^{{q_1}}}{z_1}, \ldots ,{t^{{q_m}}}{z_m})

the diagonal

C

∗

{{\mathbf {C}}^ \ast }

-action on

C

m

{{\mathbf {C}}^m}

. Then the orbit space

C

m

−
{
0
}

/

C

∗

{{\mathbf {C}}^m} - \{ 0\} /{{\mathbf {C}}^ \ast }

is a normal analytic space. In this paper, we shall show that

C

m

−
{
0
}

/

C

∗

{{\mathbf {C}}^m} - \{ 0\} /{{\mathbf {C}}^ \ast }

has only rational singularities and, if

δ
(

q
1

,
…
,

q
m

)
⩽
m
−
3

\delta ({q_1}, \ldots ,{q_m}) \leqslant m - 3

and

m
⩾
3
,

C

m

−
{
0
}

/

C

∗

m \geqslant 3,{{\mathbf {C}}^m} - \{ 0\} /{{\mathbf {C}}^ \ast }

is rigid, where

δ
(

q
1

,
…
,

q
m

)

\delta ({q_1}, \ldots ,{q_m})

is the positive integer defined by

q
1

,
…
,

q
m

{q_1}, \ldots ,{q_m}

.
Slicing convex bodies—bounds for slice area in terms of the body’s covariance
Authors: Hensley Douglas 
Published: July 2010

Let Q be a zero-symmetric convex set in

R

N

{{\mathbf {R}}^N}

with volume 1 and covariance matrix

V
2

I
d

N
×
N

V^2 \mathrm {Id}_{N \times N}

. Let P be a K-dimensional vector subspace of

R

n

,
K
>
N

{{\mathbf {R}}^n},K > N

, and let

J
=
N
−
K

J = N - K

. Then there exist constants

C
1

(
J
)

{C_1}(J)

and

C
2

(
J
)

{C_2}(J)

such that
\[

V

−
J

C
1

(
J
)
⩽

v
o
l

K

(
P
∩
Q
)
⩽

V

−
J

C
2

(
J
)
.

{V^{ - J}}{C_1}(J) \leqslant \mathrm {vol}_K(P \cap Q) \leqslant V^{-J}{C_2}(J).

\]
The lower bound has applications to Diophantine equations.