bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abdominal Nerve Blockade for Postoperative Analgesia after Caesarean Section
Authors: Kuppuvelumani P. , Jaradi Hema , Delilkan Alex 
Published: August 2010

AbstractA prospective study of blocking T10‐L1 with local anaesthetic, bilaterally in 30 patients undergoing caesarean section under general anaesthesia has been shown to provide effective postoperative analgesia thus requiring significantly less narcotics (mean 66.6 mg of pethidine) compared to the 30 patients in the control group (mean 163 mg of pethidine). A cocktail of 0.5% of bupivacaine with adrenaline and xylocaine 1% produced analgesia for the duration ranging from 8 to 12 hours (mean 8.4 hours). Patients with abdominal field block were awake, alert and comfortable during the immediate postoperative period. They were pain‐free sufficiently to put the babies to the breast early and frequently.
Endometriosis and Luteal Phase Defect
Authors: Moeloek F. A. , Moegny Endy 
Published: August 2010

AbstractIt has been reported that there exists a correlation between endometriosis and the luteal phase defect (LPD) as one of the determinants in infertility. In some theories, the hampered maturation of the corpus luteum is believed to be caused by the reduction of LH receptors, increase in prolactin, prostaglandin and macrophages in endometriosis.The purpose of this clinical study is to prove the hypothesis that there exists a significant correlation between endometriosis and the luteal phase defect in infertility.The samples were taken at random from 150 women with infertile marriages on whom ovulation was assumed to have occurred, from January 1981 to December 1985. The assumption that there might have occurred ovulation is determined through the observation of their basal body temperature (BBT) chart. Endometrium biopsies to diagnose the LPD were taken at the end of their luteal phase. A laparoscopy examination to diagnose the pelvic endometriosis was done in the following cycle.Of 84 patients with endometriosis, 44 (55.4%) had luteal phase defects, while the remaining 40 (47.6%) patients had no luteal phase defects. Of the 66 patients without endometriosis, 27 (40.9%) had luteal phase defects, while the remaining 39 (59.1%) did not have luteal phase defects. These differences were not significant (p > 0.05).In summary, this clinical study fails to show the existence of significant correlation between endometriosis and the luteal phase defect.
The Effect of Nicardipine on Maternal and Fetal Hemodynamics and Uterine Blood Flow in Chronically Instrumented Pregnant Goats
Authors: Matsuda Yoshio , Ikenoue Tsuyomu , Matsuda Kazuhiro , Sameshima Hiroshi , Ibara Satoshi , Hokanishi Hisahiko , Sakamoto Hiroshi 
Published: August 2010

AbstractThis study was designed to clarify the maternal and fetal hemodynamics of nicardipine (0.02 mg/kg) administered intravenously to unanesthetized, chronically instrumented pregnant goats. Nicardipine produced a significant increase in maternal heart rate and cardiac output, and a significant decrease in maternal mean arterial blood pressure and systemic vascular resistance. These changes persisted for about 30 minutes. There were no consistent changes in maternal pulmonary hemodynamics. Uterine arterial blood flow (UBF) decreased significantly (about 15%) after 5 minutes of the injection and returned to the control value within 30 minutes. A significant correlation between the decreases in UBF and maternal diastolic blood pressure was observed after 5 minutes of the injection. The fetal heart rate, blood pressure and acid‐base status did not change after the injection of nicardipine. These observations of pregnant goats suggest that nicardipine might be a useful agent for the treatment of acutely hypertensive crises in pregnant patients.
Pharmacological Characteristics of Contractile Responses of Rabbit Uterine Cervices to Electrical Field Stimulation
Authors: Okawa Toshiaki , Suzuki Yosuke , Endo Chikara , Hoshi Kazuhiko , Sato Akira , Nakanishi Hironori 
Published: August 2010

AbstractThe pharmacological characteristics of contractile responses to electrical field stimulation (EFS) of uterine cervical muscular strips taken from non‐pregnant and pregnant rabbits were investigated,in vitro. The contractile responses to EFS of both non‐pregnant and pregnant muscular strips were markedly depressed by treatment with prazosin 1 μm, while the responses were only slightly depressed by treatment with atropine 1 μM. Propranolol 1 μM did not affect the responses. Guanethidine 10 μM and tetrodotoxin (TTX) 10 μm also depressed the contractile responses to EFS of both non‐pregnant and pregnant muscular strips. However, the depressive effects of the latter 2 drugs were more marked in non‐pregnant muscular strips than in pregnant ones. These findings indicate that the uterine cervical smooth muscle is predominantly innervated with adrenergic excitatory nerve fibers. The cholinergic innerva‐tion in uterine cervical smooth muscle seems minor. Futhermore, during pregnancy, a TTX‐resistant, non‐adrenergic, non‐cholinergic component might increase the contractile response of uterine cervical smooth muscle to EFS.
Contraceptive Practice before Female Sterilization*
Authors: Thike Katherine Ba , Wai Khin Thet , Oo Nan , Yi Khin Htar 
Published: August 2010

AbstractThe reproductive profile and contraceptive practice of 402 women undergoing female sterilization at the Central Women's Hospital are presented. Most (89%) of the interviewees were urban‐dwellers and housewives with primary school education. Fifty‐two percent were between 30 and 34 years with a mean of 4.2 living children. Sixty‐nine percent were past contraceptive users, of them; 29.9% had used more than one method. A considerable gap between knowledge and practice of different methods was found. Education level and employment had a significant effect on contraceptive practice (p<0.01 and p<0.5).The majority knew and used combined oral contraceptive pills and injectable progestogens, whereas rhythm, withdrawal and barrier contraception were lesser known methods. Contraceptive use was primarily for child‐spacing whereas the main reasons for female sterilization were socioeconomic and achievement of desired family size.
Case Report: Spontaneous Pregnancy following Thymectomy for Myasthenia Gravis Associated with Premature Ovarian Failure
Authors: Chung Tony K. H. , Haines Christopher J. , Yip S. K. 
Published: August 2010

AbstractWe report the case of a 29‐year‐old woman who was diagnosed to have premature ovarian failure (POF) and myasthenia gravis at the age of 27 years. She was treated by thymectomy and pyridostigmine. Hormone replacement was started after the operation and she subsequently conceived spontaneously. We believe this is the first report of a spontaneous pregnancy after the diagnosis of POF associated with myasthenia gravis.
Treatment Failure in Malignant Gestational Trophoblastic Disease*
Authors: Byun Ji‐Soo , Yoon Young‐Don , Oh Sung‐Tack , Song Tae‐Bok , Choi Ho‐Sun , Lee Yu‐Ill 
Published: August 2010

AbstractOne hundred and thirty‐three patients with malignant gestational trophoblastic disease (GTD) were admitted. All patients (86/86) of the nonmetastatic and metastatic low‐risk groups and 89.4% (42/47) of the metastatic high‐risk group showed remission. The overall remission rate was 96.2%. Among 5 patients with brain metastases, however, only one (20%) survived. We arrived at two main conclusions. First, brain metastatic lesions did not successfully respond to therapy utilizing conventional chemotherapeutic regimens. Second, the key factors for successful outcome in brain metastases were early diagnosis and aggressive initial therapy. Therefore, early detection of brain metastases should be made with: (1) fine computerized tomography (CT) or magnetic resonance imaging (MRI), (2) measurement of the ratio of serum to cere‐brospinal fluid hCG concentration, and (3) early recognition of their clinical features.
Hormone Treatment Related Bone Mineral Content Changes in Japanese Women with Endometriosis
Authors: Fukushima Mineko , Shindo Masaaki , Sato Kozo 
Published: August 2010

AbstractThe effects of a GnRH agonist and danazol on bone mineral content (BMC) in Japanese women with endometriosis were investigated. Nineteen women with lap‐aroscopically confirmed endometriosis were treated with buserelin (900 μg/d administered intranasally, 10 cases) or with danazol (400 mg/d p.o., 9 cases) for 6 months. Trabecular BMC of the 3rd lumbar vertebra was measured using quantitative computerized tomography before treatment, at the end of treatment and 6 months after treatment by the same radiologist who was not informed about the drugs used. Serum estradiol and the biochemical parameters of bone metabolism were also measured. A significant decrease in BMC (10% on average; maximum 25.4%) was observed at the end of treatment with buserelin (p<0.01) and this loss was only partially recovered 6 months after treatment. In the danazol group, however, a slight gain in BMC was observed. Buserelin suppressed serum estrogen levels much more than danazol did. Parameters of bone resorption tended to increase in the buserelin group. Because treatment with buserelin, but not with danazol, was always associated with a significant decrease in BMC at L3, repeated usage of buserelin may lead to cumulative bone lpss in patients with endometriosis.
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome: Antenatal Ultrasound Appearance. A Case Report
Authors: Gürgan Timur , Yarall Hakan , Zeyneloglu Hulusi , Develioglu Osman , Urman Bülent 
Published: August 2010

AbstractWe report a case of megacystis microcolon intestinal hypoperistalsis syndrome the diagnosis of which was established antenatally by ultrasonographic examination.
Serum Level of Magnesium Attained in Magnesium Sulfate Therapy for Severe Preeclampsia
Authors: Phuapradit Winit , Saropala Nopadol , Haruvasin Somchai , Thuvasethakul Pichai 
Published: August 2010

AbstractSerum magnesium levels were determined in severe preeclampsia patients who were treated with magnesium sulfate infusion. Forty‐four patients with diagnosis of severe preeclampsia between 30–41 weeks gestation, given a conventional 5 g magnesium sulfate intravenous bolus infusion and 1 g/hr continous infusion and continued 24 hours postpartum, were prospectively studied. The mean pre‐treatment magnesium level was 2.3±0.3 mg/dl which was similar to those reports. The levels measured at 1/2, 1, 2, 4, 12 and 24 hours after initiation of magnesium infusion were 4.8±0.4, 4.7±0.4, 4.5±0.3, 4.7±0.3, 5.4±0.3 and 5.9±0.3 mg/dlrespectively. After delivery the levels were measured immediately, 12, and 24 hours and found to be 4.7±0.4, 4.9 ±0.4, and 5.2±0.3 mg/dl respectively. The serum magnesium levels were also varied with maternal weight, the dose regimen used in our study is appropriate for Asian pregnant women whose body weight usually less than 70 kg.
Serum Manganese Superoxide Dismutase (MnSOD) and Histological Virulence of Ovarian Cancer
Authors: Nishida Takashi , Sugiyama Toru , Kataoka Akio , Tashiro Masamichi , Yakushiji Michiaki , Ishikawa Mutsuo 
Published: August 2010

AbstractThe serum level of a scavenging enzyme, manganese superoxide dismutase (MnSOD), was examined in 78 patients with ovarian cancer. Tumors included 27 stage I, 6 stage II, 37 stage III and 8 stage IV diseases. They were classified as 43 serous, 18 mucinous, 10 clear cell and 7 endometrioid neoplasms, and grouped into 25 grade I, 27 grade II and 26 grade III cancers. Factors affecting the MnSOD level were estimated by analysis of variance and Bonferroni t‐test. From these, both the stage and histology were less‐effectively affected by the level, while the histological grade was estimated as effective with p<0.05. The MnSOD value increased significantly in accordance with the escalation of the tumor grade with p=0.02 for grade I vs II, 0.005 for II vs III, and 0.0001 for I vs III respectively. MnSOD determination may be unique as a predictor of the histological virulence of ovarian carcinoma.
Studies on the Permeability and Enzyme‐Cytochemistry of the Mouse Hemotrichorial Placenta*
Authors: Matsubara Shigeki , Tamada Taro , Sayama Masaaki , Saito Takuma 
Published: August 2010

AbstractThe permeability of higher molecular weight substances was investigated in mouse chorioallantoic labyrinthine hemotrichorial placenta, using horseradish peroxidase as a tracer. At the same time, ultrastructural localizations of some important enzymes, such as alkaline phosphatase (ALP), acid phosphatase (ACP), Ca++‐ATPase and guanylate cyclase were elucidated in this organ by means of the enzyme‐cytochemical technique.Peroxidase easily entered the space between layers I and II, and no penetration of this tracer beyond layer II was observed. The reaction products for ALP activity were found mainly on the maternal side of the plasma membrane of the layer II tro‐phoblast. ACP activity was confined to the lysosomes of this layer II cell. In short, peroxidase stopped at the cell surface of the layer II trophoblast, and both ALP and ACP coexisted in this layer II cell. These observations strongly suggest that the layer II trophoblast, especially the surface plasma membrane of this cell, may have an important role in regulating the materno‐fetal transfer of substances in mouse chorioallantoic placenta.
Development and Evaluation of a Computer Expert System for the Management of Fetal Distress
Authors: Wong K. K. , Ng K. H. , Nah S. H. , Yusof K. , Rajeswari K. 
Published: August 2010

AbstractThe general lack of specialist obstetricians in a developing country such as Malaysia prompted us to develop a computer expert system for the management of fetal distress in rural hospitals. It was based on accepted production rules and implemented on a microcomputer. The clinical prototype was evaluated by 8 specialist obstetricians and 21 non‐specialist doctors involved in obstetric care. The initial impression was that this type of expert system may help in diagnosis, decision‐making and teaching.
Intrauterine Pressure: Comparison of Extra vs Intra Amniotic Methods Using a Transducer Tipped Catheter
Authors: Chua Selina , Arulkumaran S. , Yang Mary , Steer Philip J. , Ratnam S. S. 
Published: August 2010

AbstractFourteen women admitted in early labor, with intact membranes, were studied. In each woman, two catheters were inserted transcervically; one catheter was inserted into the extraamniotic space before rupture of membranes, and the second catheter was inserted, after artificial rupture of membranes into the intraamniotic cavity. The contraction to contraction difference in active pressure (pressure above the baseline) recorded by the two catheters, as well as the cumulative total active pressure generated (calculated be adding the active pressure of all contractions) throughout labor by the two catheters were compared. Of the 606 contractions analysed, 43.2% showed pressure difference of 0–5 mmHg between the intra amniotic and extraamniotic catheter; 21.3% showed 6–10 mmHg difference, 12.2% showed a difference of 11–15 mmHg, and 23.3% showed a difference greater than 15 mmHg. When total active pressure generated by each catheter for individual patients was calculated, the percentage difference varied from 2.3% to 53.7%. Intrauterine pressure measurements in labour using transducer‐tipped catheters inserted in the extraamniotic space may not provide comparable information to a similar catheter inserted intraamniotically when membranes are ruptured.
Transient Blindness in Pregnancy Induced Hypertension
Authors: Achanna Siva , Monga Deepika , Sivagnanam  
Published: August 2010

AbstractSudden blindness in pregnancy is a devastating experience for the patient, her family and the treating obstetrician. Four cases of cortical blindness with pregnancy induced hypertension are presented, seen at the General Hospital Kota Bharu, Kelantan, in 1990. The incidence at the GHKB was 1: 1559 (4 cases out of 6,237 deliveries) which is higher as compared to neighbouring Singapore. The pathophysiology of this condition is still not well understood, though it is hoped that newer sophisticated imaging techniques like magnetic resonance imaging (MRI), CT scan, and blood flow waveform analysis by Doppler ultrasound will throw some light on the subject.Two of our cases presented with antepartum and two with postpartum cortical blindness. Therefore, termination of pregnancy alone may not provide the solution to this therapeutic dilemma.
A Case of Recurrent Intramural Uterine Stromal Tumor with Epithelial Differentiation Effectively Treated with Oral Low‐Dose Administration of Etoposide
Authors: Seki Hiroyuki , Takagi Akiyoshi , Takada Shinichi , Takeda Satoru , Kinoshita Katsuyuki , Masunaga Atsuko , Sugawara Isamu , Itoyama Shinji 
Published: August 2010

AbstractA 66‐year‐old woman was diagnosed as having myoma of the uterus and total hysterectomy with bilateral salpingo‐oophorectomy was performed. The histopathological findings were puzzling, and the case was finally diagnosed as intramural uterine stromal tumor with epithelial differentiation. Three years after the operation, a firm tumor developed in the pelvic cavity. Laparotomy failed to remove the tumor and neither CAP (cyclophosphamide 500 mg, adriamycin 50 mg, CDDP 70 mg) therapy nor radiation therapy was effective. Oral administration of etoposide (25 mg/day), however, showed PR (50% decrease) as determined by CT scanning, and ultrasonography, and no me‐tastatic lesions were found.This tumor was coincident with the endometrial stromal tumor with epithelial elements classified by Clement and Scully. The histological feature of the tumors and the efficacy of oral etoposide therapy are discussed in this study.
Autologous Blood Transfusion Using Recombinant Human Erythropoietin in Radical Hysterectomy
Authors: Yamawaki Takaharu , Tanaka Hirohiko , Takeuchi Shigeto , Yanase Hitoshi , Taniguchi Haruki , Toyoda Nagayasu 
Published: August 2010

AbstractThe possibility of serious complications of infection and GVHD and adverse prognosis in cancer patients resulting from homologous blood transfusions has been reported. We used recombinant human erythropoietin (rHuEPO) in autologous blood transfusions for radical hysterectomies to avoid the risks associated with transfusions.rHuEPO efficacy, stability and influence on hemodynamics were investigated. All patients were able to donate 1,200 ml of autologous blood prior to surgery, and anemia did not result despite phlebotomy three times each week. Elevation in Hb concentration was calculated at 0.78±0.37 g/dl over the first 7 days, and 2.12±0.35 g/dl over the first 14 days. No adverse side effects were observed in any patient. The serum EPO level was measured by RIA, and compared to the homologous blood transfusion group. rHuEPO did not influence postoperative EPO secretion. Autologous blood transfusion with rHuEPO in radical hysterectomy was extremely effective in mitigating the risks associated with homologous blood transfusions.
Secondary Abdominal Pregnancy
Authors: Rani P. Reddi , Pandiarajan T. , Raghavan S. Soundara , Rajaram P. 
Published: August 2010

AbstractAdvanced abdominal pregnancy is a rare event with a high fetal and maternal morbidity and mortality. We present 3 cases of abdominal pregnancy seen at our hospital. The perinatal mortality was 100% with no maternal deaths. Literature has been reviewed and management of abdominal pregnancy is discussed. Awareness of this condition and its clinical features is important in preventing abdominal pregnancy related morbidity, mortality. Careful clinical examination coupled with investigatory aids like X‐rays and ultrasound will clinch the diagnosis. Most of the patients require early laparotomy following diagnosis and the morbidity and mortality are high particularly for the fetus.
Congenital Listeriosis: Case Reports and Review of Literature
Authors: Leung Tse Ngong , Cheung Kam Lau , Wong Felix 
Published: August 2010

AbstractFour babies with congenital listeriosis were diagnosed in the Prince of Wales Hospital in Hong Kong in 1990—1991. Two died in the early neonatal period. The remaining 2 survived and recovered with no sequelae. The clinical and pathological features of these babies, together with those reported in the recent literature are highlighted so as to raise a high index of suspicion toward this disease and hopefully prompt treatment can be offered.
Long Term Results of Colposuspension Operation for Genuine Stress Incontinence
Authors: Abu‐Heija Adel T. 
Published: August 2010

AbstractA series of 88 patients were treated by a technique of modified Burch technique (colposuspension), in which the vaginal vault on each side is sutured to the iliopectineal ligament on the ipsilateral side using a pair of Dexon 1 sutures on each side. Those patients reviewed 4 years later after the operation, 88% of them were continent. There were 10 failures. The main factors associated with recurrence were previous vaginal repair (70%), pregnancy and vaginal birth after surgery (30%).This confirm that colposuspension is an effective operation for treatment of genuine stress incontinence, the success rate is high, but the selection of patients is essential, also it is important to have Cystometrogram done before surgery to avoid surgery for those patients who will not benifit from it, like those patients with detrusor muscle instability.
Pregnancy Outcome Data in a United Arab Emirates Population: What Can They Tell Us?
Authors: Hughes Phillip F. , Morrison John 
Published: August 2010

AbstractA cross‐sectional study of pregnancy outcome in a national Arabic population is presented to highlight a unique reproductive environment compared with many other obstetric populations. A high pro‐natal intensity is evident with significant numbers of grandmultipara (36.7%) and mature gravida (22.2%). These groups did not show any significant increase in adverse antenatal or intrapartum events apart from an increasing rate of gestational diabetes with maternal age. There was an average induction/augmentation rate of 10.2% with a low rate of instrumental delivery (2.3%) and a mean caesarean section rate of 6.9%. A major antenatal complication noted was the prevalance of 17.3% for a haemoglobin <10 g/dl together with overall increased rates of pre‐existing and gestational diabetes. In addition the incidence of preterm labour increased over each of the 3 years studied and is of concern.
A Study on the Hemostatic Effect of Sodium Alginate on Uterocervical Hemorrhage
Authors: Nishiya Masashi , Hareyama Hitoshi , Makinoda Satoru , Fujimoto Seiichiro 
Published: August 2010

AbstractWe examined a sodium alginate preparation (Alto®) to determine its hemostatic effect, in comparison with other topical drugs, on hemorrhages in the uterocervical area. A total of 149 patients with hemorrhage from cervical erosion or after‐treatment bleeding of the cervix uteri were subjects in this trial, and 84 (79%) of 106 patients treated with this preparation experienced a hemostatic effect.A significant positive correlation (p<0.001) was noted between the degree of tissue adhesiveness and the hemostatic effect in all the drugs tested. As for the tissue adhesiveness, Alto was significantly more favorable (p<0.001) than both Thrombin and Francetin T powder. Because Alto was softened by tissue moisture, its topical adhesiveness could be increased, which suggested that Alto was superior in hemostatis.
Breast Metastasis from Primary Cervical Cancer
Authors: Kumar Lalit , Tanwar Rajendra Kumar , Karak Prasant Kumar , Shukla Nootan Kumar 
Published: August 2010

AbstractMetastasis to the breast from primary cervical cancer is rare. A 52‐year‐old woman developed breast metastasis 6 months after the diagnosis of primary cervical cancer. The mammography showed discrete well defined nodules without microcalcification. Fine needle aspiration cytology confirmed the diagnosis. Treatment with cis‐platinum chemotherapy and local radiotherapy resulted in complete response. The patient continues to be alive and disease‐free 18 months since the diagnosis of breast metastasis.