bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioluminescent imaging of reporter gene expression in the lungs of wildtype and model mice following the administration of PEG‐stabilized DNA nanoparticles
Authors: Ziady Assem G. , Kotlarchyk Maxwell , Bryant Laura , McShane Matthew , Lee Zhenghong 
Published: March 2010

AbstractDNA nanoparticles (DNPs) formed by compacting DNA with polyethyleneglycolylated poly‐L‐lysine are a nonviral vector shown to be safe and efficacious in animals and humans. To extend our capabilities of assessing the efficacy and duration of expression achieved by DNPs, we tested the utility of bioluminescent imaging (BLI) of transgene expression in wildtype and cystic fibrosis (CF) mouse models. We tested the effect of route of administration, mouse coat color, anesthesia, dose, and promoter sequence on the level and duration of expression. Furthermore, we investigated the correlation between imaging and direct analysis of luciferase expression in lung homogenates. We found that intratracheal instillation, and the use of deep and prolonged anesthesia with avertin produced significantly higher expression compared with intranasal administration, and the use of lighter anesthesia with isoflurane. Although similar expression was observed for both dark and light coat animals, imaging signal intensity was attenuated in mice with dark fur. Furthermore, good correlation between imaging and direct homogenate analysis was observed for single dose (r = 0.96), and dose response studies in wildtype (r = 0.82) and CF mice (r = 0.87). Finally, we used imaging to track gene expression over a 56‐day time course. We found that the human ubiquitin B promoter gives stable transgene expression up to 49 days following nanoparticle administration, while expression with the cytomegalovirus promoter diminished after 2 days and returned to background levels by day 14. Taken together, our results demonstrate that BLI is an effective and useful modality for measuring gene expression conferred by DNPs in the lung. Microsc. Res. Tech. 73:918–928, 2010. © 2010 Wiley‐Liss, Inc.
Segmenting resident perceptions towards tourism — a cluster analysis with a multinomial logit model of a mountain community
Authors: Brida Juan Gabriel , Osti Linda , Barquet Andrea 
Published: March 2010

AbstractThis study investigates aspects of host perception for the formulation of strategic tourism policies. A community segmentation framework with cluster analysis and multinomial logit model was applied to data of a mountain community in northern Italy to reveal the heterogeneity of residents' perception. The results of this study reflect the overall opinions of the sample population and identify homogeneous opinion groups. Positive and negative perceptions about tourism in the region generate a division of residents in environmental supporters, development supporters, protectionist and ambivalent. This study identifies the effect of demographic variation on the clusters and on residents' attitudes towards tourism. Copyright © 2010 John Wiley & Sons, Ltd.
Incident angle dependency of propagating modes in rectangular grating for polarization‐independent −1ST order diffraction or polarization splitting
Authors: Iizuka Hideo , Engheta Nader , Fujikawa Hisayoshi , Sato Kazuo 
Published: March 2010

AbstractThe role of the incident angle of incoming light on the excited modes in rectangular grating at the interface of air and fused silica in Littrow mounting is investigated by the modal analysis.The analysis points out that the optimum effective refractive index difference for two propagating modes varies with the angle of incidence. In polarization‐independent −1st order diffraction, effective refractive index difference has the same value for the p‐ and s‐polarizations for incident angles from 30° to 37.5°, and a ratio of one‐third with the further increase of incident angle, to select the minimum aspect ratio of the grating dimensions. On the other hand, polarization splitting condition has a change of ratio of effective refractive index difference from a half to zero at an incident angle of 45.3°, where the coupling order of diffraction for p‐ or s‐polarization is also swapped. Such ratio of effective refractive index differences are seen as the ratio of modal periods in the variation of diffraction efficiency with the grating height. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1362–1369, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25163
Compact sharp‐cutoff wide‐stopband low‐pass filters using H‐shaped coupled microstrip line units
Authors: Velidi Vamsi Krishna , Sanyal Subrata 
Published: March 2010

AbstractIn this article, a single coupled‐line configuration is presented for the design of compact, sharp‐rejection, wide‐stopband low‐pass filters. The proposed filter topology consists of parallel coupled‐lines shorted at the middle. The filtering action results from the generation of three transmission zeros brought about by cross coupling. Design equations and guidelines to adjust both bandwidth and the rejection depth are provided. Theoretical predictions are validated in microstrip line by fabricating a two‐unit prototype filter having better than 25 dB stopband, which is at least five times the filter cut‐off frequency. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1402–1405, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25166
Microwave photonic frequency doubling in an RoF link DWDM system with four wave mixing
Authors: Xia Li , Aditya S. , Shum P. , Zhou Junqiang 
Published: March 2010

AbstractThe microwave photonic frequency doubling is achieved through optical carrier suppression modulation.The undesirable optical carrier and new generated optical idler light caused by four wave mixing (FWM) effect in the dense wavelength division multiplexing (DWDM) system can be blocked by a specially designed F‐P‐based FBG pair. A stable microwave frequency component at around 18 GHz with high suppression ratio to unwanted frequencies (>40 dB) is obtained after an RoF link transmission. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1428–1431, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25167
Compact dual‐mode H‐shaped filter with source/load coupling for harmonic suppression
Authors: Xiao Fei , Tang Xiaohong , Wang Ling , Wu Tao 
Published: March 2010

AbstractA compact dual‐mode H‐shaped filter with source/load coupling for harmonic suppression is proposed in this article. The compact dual‐mode H‐shaped itself has a finite‐frequency transmission zero associated with the even mode. In addition, another transmission zero can be created by introducing source/load coupling. The simulated and measured results show that the harmonic suppression of the filter can be improved by using coupled lines with loads to some extent. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1431–1434, 2010; Published online in Wiley InterScience (www.interscience. wiley.com). DOI 10.1002/mop.25168
Design and fabrication of a single‐mode optical fiber based refractive‐index sensor
Authors: Kamakshi Koppole , Rastogi Vipul , Kumar Ajeet , Rai Jagdish 
Published: March 2010

AbstractWe present a core diameter mismatch refractive index sensor designed in a single‐mode SM 600 optical fiber. The sensing region has been achieved by etching out the whole cladding and some portion of the core of the fiber. Effect of the etched core radius on sensitivity of the sensor has been investigated. Sensors response has been experimentally tested for water and acetone. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1408–1411, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25180
Compact, tunable Wilkinson power divider using tunable synthetic transmission line
Authors: Tang Wenjia , Ryu Ji‐Ho , Kim Hongjoon 
Published: March 2010

AbstractA very compact and frequency tunable Wilkinson power divider is suggested and demonstrated for the first time.By replacing λ/4 section lines in a conventional Wilkinson power divider with varactor tunable, lumped‐element synthetic transmission lines, dramatical size reduction and frequency tunability has been achieved. The prototype circuit fabricated shows excellent performance. For tunable frequencies from 0.71 to 0.99 GHz, the insertion loss is less than 3.52 dB, whereas the return loss and isolation are greater than 20 dB. Yet, the size of this voltage controllable Wilkinson power divider is only 4 mm by 8 mm, which occupies less than 3% area of original Wilkinson power divider structure. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1434–1436, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25181
Design of vertical lines for vehicle rear window antennas
Authors: Kang Woojoon , Choo Hosung 
Published: March 2010

AbstractIn this article, we propose the design of a rear on‐glass antenna for a commercial sedan. We focus on optimizing the vertical lines of the antenna and propose the optimum design parameters to maximize the matching bandwidth and improve the average vertical gain for the entire FM radio band. The detailed design parameters are determined using the Pareto genetic algorithm with an EM simulation tool. The optimized rear on‐glass antenna was built and installed on a commercial sedan. The measurement results showed a matching bandwidth of about 15%, an average bore‐sight gain of about −2.86 dBi in the entire FM band, and an average gain of about −14 dBi along the azimuth direction. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1445–1449, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25184
W‐band microstrip band‐pass filter using branch‐line coupler with open stubs
Authors: Hwang Chi‐Jeon , Lok Lai Bun , Thayne Iain G. , Elgaid Khaled 
Published: March 2010

AbstractThis article presents the design and measurement of a microstrip band‐pass filter (BPF) using modified branch‐line coupler with asymmetric open‐circuit stubs in the W‐band frequency range. The fundamental topology consists of using the branch‐line coupler as a filtering section by loading the coupled ports with suitable lengths of open‐circuit stubs. Therefore, transmission responses with simultaneously good stopband and sharp cutoff slope are derived, while the passband bandwidth can be easily controlled by means of the design parameters of the filtering section. The proposed BPF structure has been designed and fabricated on GaAs substrate. The fabricated BPF shows a 3‐dB bandwidth from 81 to 107 GHz with insertion loss <2 dB at center frequency, rejection of 51 dB, and return loss better than 18 dB. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1436–1439, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25185
A novel wideband microstrip fractal bandpass filter with a notch band at 5–6 GHz
Authors: Church Justin , West David , Dagar Pankaj , Sharma Satish K. 
Published: March 2010

AbstractThis article presents a novel wideband Sierpinski fractal stub‐based microstrip filter that provides a notch band at 5–6 GHz. The frequency bandwidth is 103% from 2.89 to 9.0 GHz, which has two passbands of 40 and 25% separated by the notch band. The filter has been designed using full wave analysis tools and has been experimentally verified. The simulated and measured results are found to be in acceptable agreement. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1413–1416, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25194
Dual‐band design of single‐stub impedance matching networks with application to dual‐band stubbed T‐junctions
Authors: Park Myun‐Joo , Lee Byungje 
Published: March 2010

AbstractA new design method of single‐stub impedance matching networks is presented for the dual‐band application. The dual‐band operating conditions are analyzed in detail and the design equations are derived in concise form for different locations and termination types of the stub line. The proposed impedance matching scheme is successfully applied to the design of a stubbed dual‐band T‐junction power divider. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1359–1362, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25201
A new impedance match method to improve efficiency of LINC with Chireix combiner
Authors: Ni Tao , Liu Falin 
Published: March 2010

AbstractIn this article, we propose a new impedance match method in serial Chireix combiner to improve the efficiency of Linear amplification with Nonlinear Components (LINC) amplifier. Based on the impedance characteristics of the serial Chireix combiner, two transmission lines are added between power amplifiers (PAs) and Chireix combiner in LINC. For experimental verification, the PAs and combiner are implemented and tested. From the measured results, this method is proved available for improving efficiency of LINC, and convenient for design as well as tuning work. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1418–1421, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25205
Design of a compact wideband bandpass filter
Authors: Packiaraj D. , Vinoy K. J. , Ramesh M. , Kalghatgi A. T. 
Published: March 2010

AbstractThis article presents the analysis and design of a compact multi‐layer layer, high selectivity wideband bandpass filter using stub loaded and ‘U’ shaped resonators over a slotted bottom ground plane. While the resonators with folded open circuit stub loadings create the desired bandpass characteristics, the ‘U’ shaped resonators reduce the size of filter. The slotted bottom ground plane is used to enhance the coupling to achieve the desired bandwidth. The proposed filter has been analyzed using circuit model, and the results were verified through full wave simulations and measurements. The fabricated filter is compact and measures a size of 18 mm × 25 mm × 1.6 mm. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1387–1389, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25206
Compact CPW‐FED matched dual‐band monopole antenna using spiral resonators
Authors: Djaiz A. , Habib M. A. , Nedil M. , Denidni T. A. 
Published: March 2010

AbstractIn this letter, a compact dual‐band monopole antenna operating at 2.45 GHz and 5.8 GHz bands using a CPW‐fed and parasitic spiral elements is presented. The monopole element creates the upper ISM band at 5.8 GHz, and the two spiral resonators is used both for impedance matching and providing the lower ISM band at frequency of 2.45 GHz. A prototype of the proposed antenna was fabricated and tested. The experimental results are presented and discussed. A good agreement between simulated and measured results is obtained. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1425–1427, 2010; Published online in Wiley InterScience (www.interscience.wiley. com). DOI 10.1002/mop.25218
Design of a wideband rectangular loop tag antenna for UHF RFID library management
Authors: Kim Uisheon , Choi Jaehoon 
Published: March 2010

AbstractIn this letter, we propose a wideband rectangular loop tag antenna for ultra‐high frequency radio frequency identification library management systems.The proposed antenna has a small matching loop for conjugate impedance matching with the impedance of a tag IC. The impedance bandwidth of the proposed antenna is broadened by lengthening the vertical sides of a rectangular loop. We considered the effects of books in designing the tag antenna. The optimized tag antenna, which is 35 mm × 90 mm in size, has a wide impedance bandwidth of 170 MHz for S11 less than −10 dB. The maximum reading distance of a single tag is about 5 m, and the concurrent reading distance of 19 arranged tags is 1 m. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1439–1445, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25219
Evaluation of EMI risk due to the interaction between cellular phones and medical devices
Authors: Chen Hsing‐Yi , Chou Cheng‐Yi 
Published: March 2010

AbstractThe FDTD method was used to calculate the electric fields emitted from cellular phones.Cellular phones were modeled by a quarter‐wavelength monopole antenna mounted on a rectangular box with equivalent material in the interior of the rectangular box and a dielectric coating in the exterior of the rectangular box. Measurements of the electric fields emitted from cellular phones were also performed by using a Narda Model SRM‐3000 high frequency selective radiation meter with an isotropicE‐field probe. From measurement and simulation results, electric fields emitted from cellular phones are in the range of 0.02–39.0 V/m for separation distances of 0–3 m between handsets and test points. It is found that field strengths emitted from cellular phones may meet the recommended EMI immunity level of 3 V/m set by the IEC for medical equipment keeping a separation distance of more than 1 m from cellular phones. An interference threshold separation distance of 3 m is proposed for evaluating the interaction between cellular phones and medical devices. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1449–1454, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25221
NMR metabolic profile of human follicular fluid
Authors: Piñero‐Sagredo Eva , Nunes Sofía , de los Santos Mª José , Celda Bernardo , Esteve Vicent 
Published: March 2010

AbstractThe environment of the oocyte during its in vivo maturation consists of follicular fluid (FF) and is surrounded by granulosa cells. The FF is derived from the sanguineous plasma and secretions, synthesised in the follicle wall, that contain a large variety of growth factors, cytokines, amino acids, and other metabolites. These metabolites are presumably involved in the physiology of the oocyte. The identification, quantification and study of FF metabolites can provide additional information about the oocyte state which can be helpful in distinguishing those oocytes that have a greater capacity to be fertilised and to develop properly. The aim of this work is to identify the metabolic profile of FF samples exhaustively using High Resolution Nuclear Magnetic Resonance (NMR). A total of 30 FF samples from oocyte donors (<35 years) were analysed. Different monodimensional (1D) and bidimensional (2D) (homo and heteronuclear) NMR experiments were acquired. A total of 131 chemical shifts were assigned and 42 metabolites, including as example glucose, lactate, acetate, acetoacetate, pyruvate and β‐hydroxybutyrate, were identified. High correlations were found between these important intermediaries of the energetic metabolic pathways of the follicle which can indicate the importance of these pathways in oocyte development. Some of these identified metabolites might be useful as biomarkers of the follicular maturation state, allowing oocytes with a higher fertilisation potential to be selected, thereby increasing pregnancy rates in women following in vitro fertilisation (IVF) treatments. Copyright © 2010 John Wiley & Sons, Ltd.
Association between gastrointestinal manifestations following acetaminophen poisoning and outcome in 291 acetaminophen poisoning patients
Authors: Zyoud Sa'ed H. , Awang Rahmat , Sulaiman Syed Azhar Syed , Al‐Jabi Samah W. 
Published: March 2010

AbstractBackgroundAcetaminophen poisoning is a common clinical problem, and early identification of patients with more severe poisoning is key to improving outcomes.PurposesThis study intends to document prevalence, clinical characteristics, and predictors of gastrointestinal (GI) manifestations and to assess the impact of these manifestations on outcome in patients with acetaminophen poisoning.MethodsThis is a retrospective cohort study of hospital admissions for acute acetaminophen poisoning conducted over a period of 5 years from 1 January 2004 to 31 December 2008. Parametric and non‐parametric tests were used to test differences between groups depending on the normality of the data. Statistical Package for Social Sciences (SPSS) 15 was used for data analysis.ResultsTwo hundred and ninety‐one patients were studied; their mean age was 23.01 ± 7.4 years and 76.6% had GI manifestations. Multiple logistic regression showed that significant risk factors for GI manifestations were present among patients who reported acetaminophen dose ingested ≥10 g (p < 0.001), and latency time more than 8 hours (p = 0.030). GI manifestations at first admission predicted poorer outcomes in terms of estimated acetaminophen levels to be a possible toxic (p < 0.001), elevated bilirubin levels (p = 0.002), prolonged prothrombin time (PT; p = 0.002), elevated creatinine level (p = 0.028), declination of potassium level (p < 0.001), and prolonged hospital stay (p < 0.001).ConclusionsGI manifestations were common among patients with acetaminophen poisoning. This study suggests that the presence of GI manifestations at first presentation appears to be an important risk marker of subsequent hepatotoxicity and nephrotoxicity. Copyright © 2010 John Wiley & Sons, Ltd.
Posttraumatic growth in breast cancer survivors: a comparison of volunteers and non‐volunteers
Authors: Cohen Miri , Numa Maya 
Published: March 2010

AbstractBackground: The need to understand posttraumatic growth (PTG) in relation to actual changes in an individual's life has recently been raised. However, the relationship of volunteering, health, and PTG has not yet been assessed.Aims: To assess the relationship of volunteer work, health, and PTG, and to assess whether cognitive and emotional processing, emotional expressing, and social support differ in volunteer and non‐volunteer breast cancer survivors.Methods: Participants were 84 breast cancer survivors who had volunteered to work with newly diagnosed breast cancer patients and 40 breast cancer survivors who did not participate in any volunteer work. Participants completed the PTG inventory, the emotional expression and processing scale, the cognitive processing scale, and the multidimensional scale of perceived social support.Results: Participants in both groups reported similar and relatively high levels of PTG (M = 70.22, SD = 17.38 in a possible range of 0–105). In the volunteer group, PTG levels were not related to self‐reported health (r = 0.07, p>0.05), while in the non‐volunteer group a high and significant correlation between self‐reported health and PTG (r = 0.46, p<0.001), and a significant effect of group×self‐reported health on PTG levels, were found. The study variables accounted for 31% of PTG variance, with cognitive and emotional processing and the interaction of group×health being significant predictors.Conclusions: Although volunteers did not differ from non‐volunteers in PTG levels, higher PTG was related to better health in the non‐volunteers group only. These findings point to the complexity of PTG structure and its multifaceted relation to behavior. Copyright © 2010 John Wiley & Sons, Ltd.