bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women's Ulama Movement in Building Moderation of Islam Indonesia
Authors: Ibi Satibi  , Mahmudah  , Endang Supriadi  
Published: June 2024

Pergerakan ulama perempuan di Indonesia dalam lintasan sejarahnya menunjukkan dinamika dan karakteristik yang dipengaruhi oleh kondisi sosial dan politik. Tulisan ini mendeskripsikan implementasi dan kontribusi Kongres Ulama Perempuan Indonesia (KUPI) yang diselenggarakan pada tanggal 25-27 April 2017 di Pondok Pesantren Kebon Jambu Babakan Ciwaringin Cirebon terhadap moderasi Islam dalam perspektif keadilan gender di Indonesia. Paper ini menjelaskan, pertama, KUPI memiliki agenda untuk memperkuat landasan keilmuan Islam dan ummat Islam dalam mengembangkan pemberdayaannya untuk mewujudkan kehidupan berkeluarga, bermasyarakat, berbangsa, dan bernegara yang sejahtera dan damai. Kedua, postulat pemikiran moderasi Islam dari perspektif gender di Indonesia. Ketiga, kontribusi teoritis-konseptual berupa lahirnya dan penguatan sudut pandang da'i yang digunakan untuk membaca makna teks-teks Islam. Selain itu, bantuan praktis penting lainnya adalah KUPI dapat mengantarkan pendirian lembaga pendidikan Islam, Ma'had Aly Kebon Jambu sebagai pusat studi yang memperhatikan Islam dan perempuan.
[The movement of female Ulama in Indonesia in its historical trajectory shows the dynamics and characteristics influenced by social and political conditions. The study describes the implementation and contribution of the Indonesian Women's Ulama Congress (KUPI) held on 25-27 April 2017 at Kebon Jambu Islamic Boarding School in Babakan Ciwaringin Cirebon against Islamic moderation in the perspective of gender justice in Indonesia. The paper talks the capability of KUPI with the plan to strengthen the scientific basis of Islam and the Muslim women's community in developing its empowerment to realize family life, community, nation, and prosperous and peaceful state. Second, postulates of Islamic moderation thinking from a gender perspective in Indonesia. Third, the theoretical-conceptual contribution in the form of the birth and strengthening of the standpoint of preachers used to read the meaning of Islamic texts. Besides, another essential practical assistance is that KUPI can deliver the advent of Islamic educational institutions, Ma'had Aly Kebon Jambu as a center of study that pays attention to Islam and women.]
The Incapability to Establish a Household as a Consequence of Child Marriage
Authors: Fadhli Ashabul , Khairiyah Ummil , Rizki Dewinda Herio 
Published: June 2024

Penelitian ini bertujuan untuk menguraikan faktor-faktor yang mendorong terjadinya perkawinan anak di Lintau Buo Utara serta mengetahui bentuk persoalan yang timbul karena perkawinan tersebut. Tidak mudah bagi anak untuk melakukan penyesuaian-penyesuaian yang kompleks sebagaimana yang diadaptasi oleh pasangan dewasa. Penelitian ini merupakan penelitian lapangan dalam bentuk kualitatif. Adapun jenis penelitian ini adalah deskriptif-analitis. Data primer diperoleh melalui wawancara terhadap 7 (tujuh) pasangan kawin anak, Kantor Urusan Agama Kecamatan Lintau Buo Utara. Data yang sudah terkumpul kemudian akan dianalisis menggunakan teori Hurlock tentang pernyesuaian sosial dalam perkawinan dengan menggunakan model interaktif Miles dan Huberman. Hasil penelitian ini menemukan bahwa minimnya pengetahuan tentang perkawinan yang berkelindan dengan persoalan sosial lainnya berakibat pada ketidaksiapan anak menjalani relasi perkawinan. Ketidaksiapan anak dalam perkawinan diketahui telah mempengaruhi kondisi sosial anak yang diantaranya adalah sulit melakukan penyesuaian diri dan gangguang emosi. Realitas sosial ini telah menekan psikologi anak karena tidak adanya kematangan emosi anak sebelum menikah. [This study aimed to describe the factors that encouraged child marriage in the Lintau Buo Utara Sub-district and find out the problems that arose from the marriage. Unlike adult couples, it is difficult for children to make complex adjustments towards marriage. This research is a field study in the form of qualitative. The type of research used in this study is descriptive analytics. The primary data were obtained through interviews with 7 (seven) child-married couples and from the Religious Affairs Office of Lintau Buo Utara. The collected data were then analyzed using Hurlock’s theory of social adjustment in marriage and Miles and Huberman’s interactive model. The results of this study showed that the lack of knowledge about marriage that was intertwined with other social problems resulted in the unreadiness of children to undergo marital relations. The unreadiness of children in marriage also affected their social conditions, which included facing difficulties in adjusting themselves and having emotional disturbances. This social reality suppressed the psychology of children because there was no emotional maturity before marriage.]
Biological engineering – an engineering discipline crucial to the future of our civilization
Authors: Adamy Jürgen , Nuber Ulrike A. , Koeppl Heinz , Bretthauer Georg 
Published: June 2024

Abstract
Biological engineering is a new engineering discipline that is paving the way for new products and processes based on findings from biology. These allow for environmentally friendly production, use and disposal while at the same time creating high added value. Like any engineering discipline, biological engineering requires a sound university education, which is already being provided at many North American universities. The aim of the article is to motivate policymakers to take note of this development and to establish comparable departments and degree programs in the EU.
Non-linear influences of track dynamic irregularities on vertical levelling loss of heavy-haul railway track geometry under cyclic loadings
Authors: de Melo Andre Luis Oliveira , Kaewunruen Sakdirat , Li Ting , Goto Keiichi 
Published: June 2024

Abstract
With an emphasis on the combined degradation of railway track geometry and components, a new numerical-analytical method is proposed for predicting the track geometrical vertical levelling loss (VLL). In contrast to previous studies, this research unprecedentedly considers the influence of initial track irregularities (ITI) on VLL under cyclic loadings, elastic-plastic behaviour, and different operational dynamic conditions. The non-linear numerical models are simulated using an explicit finite element package known as LS-Dyna, and their results are validated by full-scale experimental and field measurement data. The outcomes are iteratively regressed by an analytical logarithmic function that cumulates permanent settlements, which innovatively extends the effect of ITI on VLL in a long-term behaviour. For a typical heavy-haul railway operating under 30 tons axle load and 60 km/h train velocity, the result indicates that the set of ITI with the highest standard deviation (SD) of vertical profile (VP) degrades faster (37% on average) than that with the lowest SD. Additionally, our new findings reveal that the worst scenario is related to a train running at 60 km/h and carrying a load of 20 tons/axle in an uneven track whose SD of VP evolves from 3.23 mm at N = 0 (ITI) to 7.20 mm, whereas the best one corresponds to a train at 60 km/h and 30 ton axle load in an uneven track whose SD of VP downgrades from 0.48 to 1.50 mm, both at 3 M cycles (or 60 million gross tons). These findings indicate the importance of considering the ITI for predicting track geometrical VLL under cyclic loadings. Therefore, based on this research, an acceptable condition (thresholds) of ITI can be redefined for a minimum effect on VLL, which can support the development of practical maintenance guidelines to extend the railway track service life.
Performance of carbon nanomaterials incorporated with concrete exposed to high temperature
Authors: Han Seungyeon , Hossain Mohammad Shakhawat , Ha Taeho , Yun Kyong Ku 
Published: June 2024

Abstract
In recent decades, there have been initiatives to incorporate carbon nanomaterials (CNMs) into cement composites, particularly graphene oxide (GO), carbon nanotubes, graphite (GP), and mild carbon (MC). Nevertheless, little is known about how these CNMs interact with the cement matrix itself. In this research, the impact of CNM incorporation at high temperatures (250, 500, 750, and 1,000°C) on cement’s mechanical characteristics and microstructure was investigated. Nine mixes were created with the CNM content (0.1 and 0.3%) being taken into consideration. The microstructure of the CNM composites was further investigated using X-ray diffractometry, thermogravimetry, derivative thermogravimetry, digital microscopy, and micro-computed tomography (micro-CT). Based on research observations, the study demonstrated that the mechanical properties of most specimens could be enhanced through the introduction of CNMs. The recommended proportions of GP-0.1, GO-0.1, and MC-0.1, in accordance with the weight of the binder, and the impact of the CNMs on the elastic modulus were also assessed. As a consequence, the CNM’s porous structure and apparent crack pattern were identified using microstructure analysis.
Predominance of CD4+ T cells in metastatic cervical lymph nodes in papillary thyroid carcinoma
Authors: Moma Camila Aparecida , Barreto Icléia Siqueira , Assumpção Ligia Vera Montali , Zantut-Wittmann Denise Engelbrecht 
Published: June 2024

Background
Papillary thyroid carcinoma has become increasingly prevalent over the years. Avoiding unnecessary treatments and the risk of complications is essential, as well as understanding the mechanisms of tumor progression and the conditions that indicate a worse prognosis. Assessment of the tumor microenvironment can allow us understand how the immune system organizes itself to contain neoplastic progression.

Methods
We compared characteristics related to the lymphocytic subpopulations in the thyroid tumor microenvironment and lymph nodes in two groups, with and without lymph node metastatic involvement.

Results
Of the 400 cases followed up at a thyroid cancer reference service, 32 were selected, of which, 13 cases did not present lymph node metastasis (N0 group) and 19 had lymph node involvement (N1 group). Clinical data were collected, and immunohistochemical reactions were performed for markers CD4, CD8, FoxP3, CD25, and CD20 in lymph nodes and peritumoral infiltrate. We found that the N1 group had larger tumor sizes, higher risk staging, higher frequency of extrathyroidal extension, shorter disease-free times, and higher expression of CD4+ T lymphocytes in lymph nodes; however, there was no difference in the expression of other markers or in the pattern of lymphocyte distribution in the lymph node.

Conclusion
In cervical lymph nodes, the higher frequency of CD4+ T lymphocytes is related to the presence of metastasis. However, there were no differences in lymphocytic subpopulations in the thyroid tumor microenvironment. The absence of changes in unaffected lymph nodes could not predict any tumor behavior.
Assessment of retinal atrophy in mixed breed dogs using spectral domain optical coherence tomography (SD-OCT) and electroretinography
Authors: Balicki Ireneusz , Szadkowski Mateusz , Balicka Agnieszka , Lew Marcin , Trbolova Alexandra 
Published: June 2024

AbstractThe aim of the study was to characterize retinal atrophy (RA) with progressive retinal atrophy symptoms in mixed breed dogs using ophthalmoscopy, spectral domain optical coherence tomography (SD-OCT) and electroretinography (ERG).The study was performed on 13 mixed breed dogs affected by retinal atrophy (11 males and 2 females that were 1.5–14 years old). Depending on the advancement of RA, SD-OCT examinations identified retinal abnormalities ranging from layer disorganisation to advanced atrophy. The most advanced RA occurred ventral to the optic disc. Total retinal thickness in both eyes (mean ± SD) was lower in dogs with RA compared to controls dorsally (77.7 ± 39.5 μm vs 173.5 ± 13.3 μm), ventrally (33.4 ± 29.9 μm vs 139.5 ± 10.8 μm), nasally (65.0 ± 34.5 μm vs 163.9 ± 11.0 μm) and temporally (61.8 ± 41.7 μm vs 171.9 ± 11.1 μm) to the optic disc. In dogs with locally normal architecture of inner retina, loss of definition of outer retinal layers occurred in many regions. Dark and light-adapted ERGs were reduced in 2 dogs with RA and were unrecordable in 11 dogs. Lesions evident in SD-OCT scans of mixed breed dogs affected with retinal atrophy initially appear ventrally to the optic disc and ventro-dorsally in advanced RA. In all mixed breed dogs with retinal atrophy, clinical signs and SD-OCT results correlate with ERG findings.
Combined effect of hypertension and smoking on the death risk: data from a long-term 34-year prospective observation of Tomsk population
Authors: Dolgalev I. V. , Ivanova A. Yu. , Kim Yu. Ch. 
Published: June 2024

Aim. To assess the risks of all-cause and cardiovascular mortality in smokers with hypertension (HTN) based on the results of a 34-year prospective observation of a Tomsk population.Material and methods. The study included 630 men and 916 women aged 2059 years who underwent primary screening in 1988-1991. HTN was established with blood pressure (BP) ³140/90 mm Hg and <140/90 mm Hg in persons taking antihypertensive drugs. People who smoked ³1 cigarette per day or stopped smoking less than a year ago were classified as smokers, and those who stopped smoking for more than one year were classified as non-smokers. Over 34-year observation, 535 deaths were identified, of which 232 were from cardiovascular causes.Results. The combination of hypertension and smoking increases the relative risk (RR) of all-cause death by 3,4 times in the general population, by 2,6 times among men and by 3,4 times among women. The risk of cardiovascular death also increases (RR 3,6). This effect was most pronounced among people in the younger age group (RR 8,5). Hypertensive smokers had a 1,5 times higher risk of premature all-cause death compared with nonsmokers with hypertension. Multivariate analysis found that smoking, regardless of other predictors, increases the all-cause and cardiovascular death risk by 2,61 and 2,77 times, respectively. HTN increases allcause and cardiovascular death risk by 1,32 and 1,52 times, respectively.Conclusion. Hypertension and smoking are among the most influential modifiable risk factors for premature death, and their combination increases the RR of allcause and cardiovascular death by 3,4 and 3,6 times, respectively. A more unfavorable prognosis has been established for women and young people. When HTN and smoking are combined, the 34-year survival prognosis decreases to 30,8% compared to 79,3% in individuals without these risk factors.
Point-of-care N-terminal pro-brain natriuretic peptide testing in patients with heart failure: data from the DREAM study
Authors: Belyalov F. I. , Lozhkina N. G. , Shtegman O. A. , Yagudina R. N. , Kankharey O. V. , Reshina I. V. , Sergeeva E. E. , Belyalov D. F. , Belyalova N. S. , Zhilokov Z. Kh. , Aleynikova A. V. , Medvedeva E. A. , Kharitonov A. A. 
Published: June 2024

Aim.To compare the blood levels of N-terminal pro-brain natriuretic peptide (NTproBNP), determined using a Russian semi-quantitative point-of-care test and quantitative laboratory tests, depending on the presence and severity of heart failure (HF) and left ventricular (LV) function.Material and methods.This Diagnosis of chRonic hEart fAilure using a NTproBNP test Multicenter study (DREAM) was conducted in 79 patients with HF and 24 healthy individuals. Blood NT-proBNP concentrations assessed using an immunochromatographic semiquantitative rapid test were compared with quantitative laboratory test results, severity of heart failure, and LV function.Results.The study showed that the NT-proBNP rapid test results were highly correlated (correlation coefficient 0,74) with the quantitative test. The NT-proBNP level assessed by the rapid test increases in patients with higher NYHA HF class and does not differ significantly from the quantitative test grades. The sensitivity, specificity, positive predictive value, and negative predictive value of the test result relative to natriuretic peptide quantification were 0,97, 0,78, 0,91, and 0,93, respectively. Sensitivity, specificity, positive and negative predictive value of the test result regarding NYHA classes II-IV were 0,95, 0,85, 0,95 and 0,85, and regarding LV ejection fraction <50% — 1,0, 0,24, 0,24, and 1,0, respectively. False-positive rate in the healthy individuals' group were low (4%).Conclusion.The results of the NT-proBNP rapid test demonstrated acceptable diagnostic accuracy compared to quantitative assessment in patients with HF of varying severity and LV ejection fraction.
Inhospital outcomes of implantation of a centrifugal left ventricular assist device in patients with endstage heart failure: experience of the Chazov National Medical Research Center of Cardiology
Authors: Ganaev K. G. , Dzybinskaya E. V. , Narusov O. Yu. , Vlasova E. E. , Amanatova V. A. , Shakhramanova Zh. A. , Latypov R. S. , Mershin K. V. , Pevzner D. V. , Tereshchenko S. N. , Shiryaev A. A. , Akchurin R. S. , Boytsov S. A. 
Published: June 2024

Aim. To study the inhospital outcomes of implantation of a centrifugal left ventricular assist device (LVAD) in patients with end-stage heart failure (HF).Material and methods. There were following inclusion criteria: estimated body surface area >1,2 m2, end-stage HF, LV ejection fraction <30%, cardiac index <2,2 l/min, long-term optimal therapy for HF. Patients were considered for implantation of a centrifugal (LVAD) as part of the final therapy, but subsequent heart transplantation was not ruled out if appropriate.Results. LVAD was implanted in 23 patients. All patients were men (mean age, 59,1±10 years; mean body mass index, 26±4,6 kg/m2). Ten patients had dilated cardiomyopathy, while 13 — ischemic one. Diabetes was revealed on in 3 (13%) patients, while chronic kidney disease and cancer — in 3 (13%) and 4 (17%) patients, respectively. The mean value of the six-minute walk test (6MWT) upon admission to the hospital was 257±71 meters. In one patient with gastric cancer, the device was implanted as a part of bridging therapy strategy. Thirty-day mortality was 9% (n=2). One of the deceased patients had a long history of end-stage heart failure, body weight deficiency, and frailty with severe muscle weakness. The second death was the result of early postoperative right ventricular failure. At discharge, patients had optimal LVAD performance based on anthropometric characteristics and physical activity. According to echocardiography, the criteria for unloading the left heart chambers have been achieved. The distance of 6MWT at discharge was 298±78 meters.Conclusion. Inhospital outcomes of implantation of a centrifugal LVAD in patients with end-stage HF demonstrate high efficiency in supporting systemic hemodynamics with an acceptable safety profile in patients with extremely high perioperative risk.
Effectiveness of inclisiran lipid-lowering therapy in patients with atherosclerotic cardiovascular disease in Moscow healthcare
Authors: Sapina A. I. , Varlamova Yu. Yu. , Papyrina M. G. , Bezymyanny A. S. , Kordzaya E. L. , Vasilyeva E. Yu. 
Published: June 2024

Aim. To evaluate the effectiveness of PCSK9-targeted therapy (inclisiran, alirocumab, and evolocumab) in patients with atherosclerotic cardiovascular disease (ASCVD) and who did not achieve the target low-density lipoprotein cholesterol (LDL-C) level on basic therapy (statins in maximum tolerated doses and/or ezetimibe).Material and methods. This observational study included 50 patients receiving the inclisiran and 30 patients of the control group with ASCVD treated with PCSK9 inhibitors (alirocumab, n=1; evolocumab, n=29). In all participants, we assessed medical history data and initially performed electrocardiography, echocardiography, Doppler ultrasound of extracranial and lower limb arteries, and laboratory tests (complete blood count, biochemical and lipid profile). Three Moscow public health facilities took part in the study.Results. Data on achievement of primary and secondary endpoints by the 12th month are presented. The study groups were comparable in basic clinical characteristics. In inclisiran group, a significant decrease in LDL-C level was found from 2,53±0,7 mmol/l initially to 1,29±0,5 mmol/l (by 49%), p=0,0002; the target LDL-C <1,4 mmol/l was achieved by 73,9% of the subjects. Alirocumab/ evolocumab showed significant lipid-lowering effect with a LDL-C decrease from 2,4±0,9 mmol/l to 1,32±0,7 mmol/l (by 45%), p<0,0001.Conclusion. The final results are consistent with the intermediate data and indicate not only the possibility of early achievement of target LDL-C levels in PCSK9targeted combination therapy, but their maintenance with a favorable tolerability and safety profile.
Lo que piensan, dicen y hacen los docentes rurales. Narrativas socio ambientales del territorio
Authors: Marín Mejía Milena 
Published: June 2024

El presente escrito presenta los resultados de una investigación que analiza las reflexiones y prácticas asociadas a la Educación Ambiental de un grupo de docentes rurales adscritos a la Secretaría de Educación de Antioquia, quienes participaron en una experiencia de formación. Así que desde una perspectiva cualitativa-interpretativa se analizaron las narrativas audiovisuales elaboradas por los participantes las cuales permitieron reconocer lo que piensan, dicen y hacen en relación con los retos y problemáticas ambientales del territorio. En este sentido, las narrativas como técnicas de recogida de datos, posibilitaron a los docentes externalizar los sentires de los docentes, y a partir de un análisis de contenido, se reconocieron las iniciativas que se están llevando a cabo en algunas instituciones educativas rurales y sus características desde una mirada singular propia de cada contexto, que son determinantes al momento de emprender cualquier acción transformadora.