bluuebunny/crossref_metadata_2025_split huggingface dataset:
Important considerations for craniofacial mapping using laser scanners
Authors: Majid Zulkepli , Chong Albert K. , Setan Halim 
Published: July 2010

AbstractThe use of a laser scanning system for human craniofacial mapping has gained considerable interest recently as it offers a non‐contact method which is very efficient in capturing a vast amount of accurate spatial data. Nonetheless, there is a need for a thorough evaluation to identify the important technical factors which may affect the accuracy of the system. This paper discusses the tests and the results of an evaluation of the Minolta VI‐910 3D laser scanning system used to capture craniofacial surface data. The research shows that the factors to consider for craniofacial mapping are: scan distance, camera focal length, laser beam intensity, scanning resolution, convergence angle and number of overlapping scans.
Familial Loading for Alcoholism and Offspring Behavior: Mediating and Moderating Influences
Authors: Molina Brooke S. G. , Donovan John E. , Belendiuk Katherine A. 
Published: July 2010

Background:  Familial loading for alcoholism is an important marker of risk for early‐onset alcohol problems, but the early expression of this risk in community samples of children is understudied.Methods:  This study tested, for 452 8‐ and 10‐year‐old children, whether the density of alcohol problems in their biological relatives was associated with externalizing behaviors that are risk factors for later alcohol problems.Results:  Density of alcohol problems in first‐ and second‐degree biological relatives was associated with behavioral disinhibition (BD; e.g., poor inhibitory control, attentional shifting, β = 0.10, p = 0.04) and conduct problems (CP; i.e., defiance, aggression, delinquency, β = 0.18, p = 0.00). These relations were moderated by parenting practices (parental warmth, discipline consistency, and parental monitoring). The density‐behavior association lost statistical significance when at least 2 of 3 parenting practices were rated above median levels for the sample (p = 0.67 to 0.36). The density‐behavior association was mediated by current demographic advantage (p = 0.00 for BD, p = 0.00 for CP), current maternal mental health (p = 0.01 for BD, p = 0.00 for CP), and current maternal deviant behavior (for CP only, p = 0.01).Conclusions:  Findings support previously proposed but untested pathways in etiologic models of alcoholism and show the potentially important role of active parenting in reducing the expression of inherited vulnerability to alcoholism in childhood.
Right‐Sided Free Wall Accessory Pathway Refractory to Conventional Catheter Ablation: Lessons From 3‐Dimensional Electroanatomic Mapping
Authors: CHEN MINGLONG , YANG BING , JU WEIZHU , CHEN HONGWU , CHEN CHUN , HOU XIAOFENG , ZHANG FENGXIANG , CUI JUNYOU , ZHANG CHUANHUAN , SHAN QIJUN , ZOU JIANGANG , SUN JUNPING , XI YUTAO , CHENG JIE , CAO KEJIANG 
Published: July 2010

Right Free Wall Accessory Pathway Ablation. Introduction: The aim of this study was to delineate the electroanatomic substrates of right‐sided free wall (RFW) accessory pathways (APs) that were refractory to conventional catheter ablation utilizing 3‐dimensional (3‐D) mapping.
Methods and Results:
Eleven patients with RFW APs that failed initial conventional catheter ablation(s) by a mean of 1.9 ± 0.5 attempts were enrolled in the study. Electroanatomic mapping of the right atrium was performed during orthodromic reciprocating tachycardia in 3 patients and right ventricular pacing in 8 patients. The earliest atrial activation site, which represented the atrial insertion of the AP, was separated from the tricuspid annulus by an average of 14.3 ± 3.9 mm, and the local activation time was 27.8 ± 17.0 ms earlier than that of the corresponding annular point. One patient exhibited an AP with wide branching on the atrial side. RF ablation with an irrigated catheter successfully interrupted AP conduction in all patients without complications.
Conclusions:
RFW APs resistant to conventional catheter ablation might be due to unique anatomic AP features such as more epicardial course at the annulus level with atrial insertion distant from the tricuspid annulus. Electroanatomic mapping is helpful to accurately localize the atrial insertion sites of these APs and facilitates catheter ablation. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1317‐1324, December 2010)
Capsaicin‐induced neurogenic inflammation in the skin in patients with symptoms induced by odorous chemicals
Authors: Holst Helle , Arendt‐Nielsen Lars , Mosbech Holger , Serup Jørgen , Elberling Jesper 
Published: July 2010

Background: Intradermal injection of capsaicin induces the axonal release of neuropeptides, vasodilatation and flare, e.g. neurogenic inflammation. The spatial profile of neurogenic inflammation in the skin has been studied in various experimental models. Polarization spectroscopy imaging introduced recently may be used for the quantitative assessment of the temporal profile of neurogenic inflammation expressed as erythema intensity.Purpose: In the present study, we aimed to compare capsaicin‐induced erythema intensity with the flare area in patients with symptoms induced by odorous chemicals, thereby comparing the temporal and spatial profiles of neurogenic inflammation.Methods: Sixteen patients fulfilling Cullen's criteria for multiple chemical sensitivity (MCS) and 15 eczema (EC) patients with airway symptoms elicited by odorous chemicals were compared with 29 age‐matched, healthy controls. Participants were administered two intradermal injections of capsaicin 3.3 and 33 μM. Erythema intensity was measured by polarization spectroscopy imaging and flare response was quantified by visual inspection.Results: Erythema intensity and flare area did not differ between patients and controls, and they were not correlated. Erythema intensity and flare area showed a dose‐dependent increase (P<0.05). Erythema intensity increased with age at 3.3 μM but not at 33 μM capsaicin, whereas the flare area increased with age at both concentrations (P<0.05).Conclusion: Capsaicin‐induced erythema intensity and visual flare were normal in patients with MCS and EC patients with airway symptoms from odorous chemicals. Polarized light spectroscopy was a useful method for the measurement of the rapid temporal changes in erythema of experimental reactions.
Late and ultra late onset Streptococcus B meningitis: clinical and bacteriological data over 6 years in France
Authors: Guilbert J , Levy C , Cohen R ,   Bacterial meningitis group, Delacourt C , Renolleau Sylvain , Flamant Cyril 
Published: July 2010

AbstractBackground:  Group B Streptococcus (GBS) is one of the leading causes of sepsis and meningitis in newborn. The objective of this study was to describe the characteristics of GBS meningitis in children aged between 7 and 89 days (late onset disease – LOD group) and to compare them with children aged more than 3 months (ultra late onset disease – ULOD group).Methods: Clinical and biological data were gathered by ACTIV/GPIP (a nationwide active surveillance network). The study population included 242 children hospitalized between 2001 and 2006 for GBS meningitis (220 in the LOD group and 22 in the ULOD group).Results:  Univariate analysis revealed that gestational age (GA) was significantly lower in the ULOD group as compared with the LOD group (respectively 35.6 weeks vs. 37.9 weeks, p = 0.002). Prevalence of early preterm birth (before the 32nd week GA) was significantly higher in the ULOD group than in the LOD group (32% vs. 7%, p = 0.002). No significant difference was found between the two groups for biological characteristics of lumbar puncture, GBS serotypes, complications and survival rate.Conclusion: These data suggest that LOD and ULOD would be the same clinical and bacteriological entity, except for prematurity, which seems significantly associated with ULOD.
THE BOOK SHELF
Authors: Bailey Franklin C. 
Published: July 2010

Books reviewed in this article:1. Bard, Morton, Ph.D., Training Police As Specialists in Family Crisis Intervention.2. Eck, Marcel, Lies and Truth.3. From, Erich, The Revolution of Hope.4. Howard, Jane, Please Touch.5. Hunt, Morton, The Affair.6. Lowen, Alexander, M.D., Pleasure: A Creative Approach to Life.7. Masters, William H. and Virginia E. Johnson, Human Sexual Inadequacy.7A. Belliveau, Fred, and Lin Richter, Understanding Human Sexual inadequacy.8. Mindey, Carol, The Divorced Mother.9. Watson, Andrew S., M.D., Psychiatry for Lawyers.
THE BOOK SHELF
Authors: Bailey Franklin C. 
Published: July 2010

Books reviewed in this article:1. Block, Dr. William A. What Your Child Really Wants to Know About Sex – And Why.2. Bingham, Sallie. The Way It Is Now.3. Charny, Dr. Israel. Marital Love and Hate.4. Cooper, Boyd, M.D. Sex Without Tears.5. Cuse, Arthur R. Financial Guideline: Divorce.6. Evslin, Dorothy. The Fortunate Sex.7. Gorney, Roderil, M.D. The Human Agenda.8. Halsell, Grace. Black/White Sex.9. Hart, Harold (Ed.). Marriage: For and Against.10. Kavanaugh, James. Faces In the City.11. Satir, Virginia. Peoplemaking.12. Steincrohn, Peter J., M.D. Antidotes for Anxiety.13. Stuart, Irving R., Ph.D. and Lawrence Edwin Abt, Ph.D. Children of Separation and Divorce.
THE BOOK SHELF
Authors: Hulbert E. Ronald 
Published: July 2010

NICHOLS, William C., Jr., (Editor) Marriage and Family Therapy: A Reader from the NCFR JournalsFERBER, MENDOLHSON & NAPIER, The Book of Family TherapyGARDNER, Richard A., M.D., The Boys and Girls Book About DivorceBURR, Wesley R., Theory Construction and the Sociology of the Family
THE BOOK SHELF
Authors: Hulbert E. Ronald 
Published: July 2010

FAMILY THERAPY: AN INTRODUCTION TO THEORY & TECHNIQUE, Edited by G. D. Erickson and T. P. HoganHELPING YOUR CHILD LEARN RIGHT FROM WRONG, by Sidney Simon, Ph.D. and Sally W. OldsTREATING RELATIONSHIPS, by David H. Olson, Ph.D.
THE BOOKSHELF
Authors: Hulbert E. Ronald 
Published: July 2010

Books reviewed in this article: LAW & THE MENTAL HEALTH PROFESSIONS, Walter E. Barton & Charlotte J. Sanborn(Eds.) BEHAVIORAL ASSESSMENT: NEW DIRECTORIONS IN CLINICAL PSYCHOLOGY, John D. Cone, Ph.D. and Robert P. Hawkins Ph.D.(Eds.) NETWORKING FAMILILES IN CRISIS, Uri Rueveni, Riverside MARRIAGE AND MARITAL THERAPY, Thomas J. Paolino, Jr., M.D. and Barbara J. McCrady, Ph.D.(Eds.)
THE BOOKSHELF
Authors: HULBERT E. RONALD 
Published: July 2010

The book reviews in this article
MY MOM AND DAD ARE GETTING A DIVORCE
, florence Bienefeld, MA, St. Paul, Minn
The Family: Evaluation and Treatment
, Edited by Charles K. Hofling, M. D. and jerry M. Lewis, M. D.
Parents as Playmates
, Joan Millman and Polly Behrmann
Human Development in Western Culture
, Harold W. Bernard
THE BOOKSHELF
Authors: Hulbert E. Ronald 
Published: July 2010

The book review in this article
MOM'S HOUSE/DAD'S HOUSE—MAKING SHARED CUSTODY WORK
, Isolina Ricci, M.A., M.F.C. Macmillan Publishing Co., Inc.
DIVORCE MEDIATION: THE RATIONAL ALTERNATIVE
, Howard H. Irving, Ph.D.
CHILDREN IN CONCILIATION THE EXPERIENCE OF INVOLVING CHILDREN IN CONCILIATION
Authors: Garwood Fiona 
Published: July 2010

ABSTRACTConciliation services in Scotland have developed rapidly since the first service, Lothian Family Conciliation Service (LFCS), was set up in Edinburgh in 1984. Conciliators in Scotland work principally with parents, but wherever possible involve children in the process. The author monitored and evaluated this work over two years. This article outlines the context of conciliation in Scotland, briefly describes the LFCS and presents the research findings on the service's involvement with children.
Simulation of dark lanes in post-flare supra-arcades – II. A contribution to the remote sensing of the coronal magnetic field
Authors: Schulz W. , Costa A. , Elaskar S. , Cid G. 
Published: July 2010

Abstract
We integrate the MHD ideal equations to simulate dark void sunwardly moving structures in post-flare supra-arcades. In Costa et al. we could numerically reproduce the observations described in Verwichte et al. We showed that the dark tracks are plasma vacuums generated by the bouncing and interfering of shocks and expansion waves, upstream an initial slow magnetoacoustic shock produced by a localized deposition of energy modelled as a pressure perturbation. The same pressure perturbation produces a transverse to the field or perpendicular magnetic shock giving rise to non-linear waves that compose the kink-like plasma void structures, with the same functional sunward decreasing phase speed and period's constancy with height, as those determined by the observations. In this Letter we accomplish a study of sensitivity to initial and background physical conditions of the phenomenon. With the aim of contributing to the remote sensing of the corona we describe the characteristics of different void structures in terms of physical conditions, i.e. magnetic field intensity and pressure perturbation, given a background density.
The Role of Private Equity in Life Sciences
Authors: Greene Jeff , Purcell Dennis , Edelman Brian , Giordano Doug , Ruback Richard , Mihas Dean , Opler Tim , Cahill Tom , Giovannetti Glen 
Published: July 2010

In a roundtable published in this journal a year ago, there was a clear consensus that the R&D function in big pharma was inefficient and in need of major restructuring, possibly through increased investments by venture capital and private equity firms. In this discussion, an accomplished group of industry practitioners begins by looking at the prospects for both venture capital and private equity to play meaningful roles in financing early‐ and mid‐stage drug development. In so doing, they explore questions like the following:

Are there ways for big pharma and biotech to reduce “science risk” and make R&D funding more profitable and attractive to venture capital and private equity—and perhaps even hedge funds?
What roles do you see for specialty PE firms like Symphony Capital and Paul Capital, which are now bundling mid‐stage development assets and securitizing royalties?

Then the panelists turn to the broader life sciences industry and consider the outlook for leveraged private equity transactions involving marketed products, late‐stage development, and services. Here they consider issues like the following:

Will PE be attracted to less‐R&D‐intensive activities like medtech and generics?
Have the recent consolidation through mergers and reorganization of big pharma into decentralized business units created opportunities for carve‐outs of certain businesses?

For big pharma and life sciences companies in general, the answers to such questions point to greater specialization and focus achieved partly through strategic alliances with venture capital, private equity, and even hedge funds, and involving marketed products and services as well as early‐stage drug development.
Smart Growth—Creating Real Long‐term Value
Authors: Hess Edward D. 
Published: July 2010

Most U.S. business leaders appear to believe that all businesses either “grow or die”—and many act as if they believed that all growth is good, and that public companies should grow in a linear, continuous manner as reflected in ever‐increasing quarterly earnings. But if these tenets of “the U.S. Growth Model” inform the short‐term business view that prevails in many C‐suites and boardrooms, there has been surprisingly little analysis of the extent to which the pursuit of continuous growth translates into longer‐run success.In this article, the author reports finding no theoretical or empirical support in the fields of economics, finance, strategy, organizational design (or biology) for the idea that continuous growth is either a realistic possibility or a useful corporate objective. In business organizations, the pursuit of continuous growth can drive bad corporate behavior and inhibit real growth and innovation. Based on extensive research, the author suggests a new model of “smart growth”—one in which companies grow successfully by building internal comprehensive systems designed to encourage growth through specific kinds of culture, leadership, and processes. Smart‐growth companies use experimental learning processes designed to test growth ideas and build diversified “growth portfolios” while also attempting to limit the risks associated with the pursuit of growth.
Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic
Authors: Ishikura S. , Koshkina A. , Klip A. 
Published: July 2010

AbstractInsulin stimulates glucose uptake into muscle and adipose tissues through glucose transporter 4 (GLUT4). GLUT4 cycles between the intracellular compartments and the plasma membrane. GLUT4 traffic‐regulating insulin signals are largely within the insulin receptor‐insulin receptor substrate‐phosphatidylinositol 3‐kinase (IR‐IRS‐PI3K) axis. In muscle cells, insulin signal bifurcates downstream of the PI3K into one arm leading to the activation of the Ser/Thr kinases Akt and atypical protein kinase C, and another leading to the activation of Rho family protein Rac1 leading to actin remodelling. Activated Akt inactivates AS160, a GTPase‐activating protein for Rab family small G proteins. Here we review the roles of Rab and Rho proteins, particularly Rab substrates of AS160 and Rac1, in insulin‐stimulated GLUT4 traffic. We discuss: (1) how distinct steps in GLUT4 traffic may be regulated by discrete Rab proteins, and (2) the importance of Rac1 activation in insulin‐induced actin remodelling in muscle cells, a key element for the net gain in surface GLUT4.
Role of adipokines in obesity‐associated hypertension
Authors: Vlasova M. , Purhonen A. K. , Jarvelin M. R. , Rodilla E. , Pascual J. , Herzig K. H. 
Published: July 2010

AbstractIt has been well documented that obesity is a major risk factor for the development of the hypertensive state. The correlation between body mass index and blood pressure level is well established. Nevertheless, the exact mechanisms which contribute to obesity‐related hypertension remain poorly understood. In the last years, we have realized that the white adipose tissue is not just an inert organ for nutrient storage and isolation but rather depending on the body mass index the biggest endocrinological organ. Thus, the possible contribution of adipokines to the blood pressure elevation becomes an attractive hypothesis to explain the hypertensive state that often occurs in obesity. In this review, we consider direct and indirect effects of main adipokines on structural and functional changes in the cardiovascular system.
Fluorescence and Photochemistry of Recombinant Phytochrome from the CyanobacteriumSynechocystis
Authors: Sineshchekov V. , Hughes J. , Hartmann E. , Lamparter T. 
Published: July 2010

ABSTRACTFluorescence and photochemical properties of phytochrome from the cyanobacteriumSynechocystiswere investigated in the temperature interval from 293 to 85 K. The apoprotein was obtained by overexpression inEscherichia coliand assembled to a holophytochrome with phycocyanobilin (PCB) and phytochromobilin (PφB), Syn(PCB)phy and Syn(PφB)phy, respectively. Its red‐absorbing form, Pr, is characterized at 85 K by the emission and excitation maxima at 682 and 666 nm in Syn(PCB)phy and at 690 and 674 nm in Syn(PφB)phy. At room temperature, the spectra are blue shifted by 5–10 nm. The fluorescence intensity dropped down by ˜15–20‐fold upon warming from 85 to 293 K and activation energy of the fluorescence decay was estimated to beca5.4 and 4.9 kJ mol−1in Syn(PCB)phy and Syn(PφB)phy, respectively. Phototransformation of Pr upon red illumination was observed at temperatures above 160–170 K in Syn(PCB)phy and above 140–150 K in Syn(PφB)phy with a 2–3 nm shift of the emission spectrum to the blue and increase of the intensity of its shorter wavelength part. This was interpreted as a possible formation of the photoproduct of the meta‐Ra type of the plant phytochrome. At ambient temperatures, the extent of the Pr phototransformation to the far‐red‐absorbing form, Pfr, wasca0.7–0.75 and 0.85–0.9 for Syn(PCB)phy and Syn(PφB)phy, respectively. Fluorescence of Pfr and of the photoproduct similar to lumi‐R was not observed. With respect to the photochemical parameters, Syn(PCB)phy and Syn(PφB)phy are similar to each other and also to a small fraction of phyA (phyA″) and to phyB. The latter were shown to have low photochemical activity at low temperatures in contrast to the major phyA pool (phyA″), which is distinguished by the high extent (ca50%) of Pr photoransformation at 85 K. These photochemical features are interpreted in terms of different activation barriers for the photoreaction in the Pr excited state.
Compound heterozygosity for a rare small deletion and a common point mutation in the beta‐globin gene: report of two Chinese families
Authors: SHANG X. , RAO Z. , LOU J. , LI W. , XIONG F. , ZHOU H. P. , XU X. 
Published: July 2010

SummaryIntroduction:  Most cases of β‐thalassemia are caused by point mutations in the β‐globin gene. Only a minority of β‐thalassemia mutations are small deletions in the exons of the β‐globin gene.Methods:  Here, we report two cases of β‐thalassemia that were caused by compound heterozygosity for a rare small deletion and a common point mutation.Results:  Patient A carried a rare 14‐bp deletion (CD89–93) mutation plus the common mutation −28(A>G). Patient B carried a rare 13‐bp deletion (CD54–58) plus the common mutation IVS‐2‐654(C>T).Conclusion:  Patient B is the second report of the CD54–58(−13 bp) deletion. However, our report differs from the previous report in two ways: we performed a family study based on multiple samples; and the carriers and patient showed an elevated level of HbF, which was not observed in the previous case.
Current Technique of Fluid Status Assessment
Authors: Frank Peacock W. , Soto Karina M. 
Published: July 2010

Congest Heart Fail. 2010;16(4)(suppl 1):S45–S51. ©2010 Wiley Periodicals, Inc.Early in the management of acute illness, it is critically important that volume status is accurately estimated. If inappropriate therapy is given because of errors in volume assessment, acute mortality rates are increased. Unfortunately, as the gold standard of radioisotopic volume measurement is costly and time‐consuming, in the acute care environment clinicians are forced to rely on less accurate measures. In this manuscript, the authors review the currently available techniques of volume assessment for patients presenting with acute illness. In addition to discussing the accuracy of the history, physical examination, and radiography, acoustic cardiography and bedside ultrasonography are presented.
Education and support for dominant ideology*
Authors: BAER DOUGLAS E. , LAMBERT RONALD D. 
Published: July 2010

Utilisant les résultats du sondage national sur la qualité de la vie de 1977, nous avons examiné les quatre hypothèses qui expliquent l'influence de l'instruction sur l'opinion publique au sujet de l'inégalitééconomique. Les hypothèses sont l'instruction, la socialisation, la reproduction, et l'investissement.L'élément français‐anglais et les différences d'âge sont examinés également. Les résultats des analyses multivariées favorisent la socialisation ainsi qu'une des versions de l'hypothèse d'investissement. Les problèmes rencontrés au cours de l'étude du concept d'une idéologie dominante et son utilité dans l'analyse du processus de légitimation au Canada, sont discutés également.Using the Quality of Life (1977) national survey, we tested four hypotheses explaining the effects of education on people's beliefs about economic inequality. The hypotheses are enlightenment, socialization, reproduction, and investment. French‐English and age differences are also examined. Results of the multivariate analyses favour the socialization and one version of the investment hypotheses. Problems in thinking about the concept of dominant ideology and its utility in analyzing legitimation processes in Canada are discussed.