bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of New-onset and Flare of Preexisting Psoriasis During Rituximab Therapy for Rheumatoid Arthritis: Data from the French AIR Registry
Authors: THOMAS LAURE , CANOUI-POITRINE FLORENCE , GOTTENBERG JACQUES-ERIC , ECONOMU-DUBOSC ANDRA , MEDKOUR FATIHA , CHEVALIER XAVIER , BASTUJI-GARIN SYLVIE , LE LOUËT HERVÉ , FARRENQ VALÉRIE , CLAUDEPIERRE PASCAL 
Published: April 2012

Objective.Psoriasis could be a paradoxical reaction to tumor necrosis factor-α antagonist therapy and it has been reported with rituximab therapy. Our objective was to assess the rates of new-onset and flare of preexisting psoriasis in patients taking rituximab for rheumatoid arthritis (RA).Methods.The nationwide multicenter prospective AutoImmunity and Rituximab (AIR) registry was set up in 2006 by the French Society for Rheumatology to collect data on patients taking rituximab for joint diseases. We identified patients with RA in the registry who had psoriasis listed as an adverse drug reaction, and we obtained additional information from their physicians if needed. We computed the incidence rates of new-onset and flare of preexisting psoriasis according to the rituximab exposure time.Results.Among the 1927 patients in the registry with RA, 2 had new-onset and 5 had flare of preexisting psoriasis after a median followup of 39.2 weeks. Incidence rates were 1.04/1000 person-years (95% CI 0.13 to 3.8) for new-onset psoriasis and 2.6/1000 person-years (95% CI 0.84 to 6.1) for flare of preexisting psoriasis. Rituximab rechallenge in the 2 new-onset cases and in 2 flare cases was not followed by recurrence or exacerbation of psoriasis. Two of the 5 flare cases developed after discontinuation of methotrexate.Conclusion.Despite the small number of cases observed, leading to wide CI, the incidence rates in our study do not support a causative role of rituximab therapy in new-onset or flare of preexisting psoriasis in patients with RA.
Correlates of Axial Gout: A Cross-sectional Study
Authors: KONATALAPALLI RUKMINI M. , LUMEZANU ELENA , JELINEK JAMES S. , MURPHEY MARK D. , WANG HONG , WEINSTEIN ARTHUR 
Published: April 2012

Objective.A cross-sectional study was undertaken to determine the prevalence of axial gout in patients with established gouty arthritis and to analyze clinical, laboratory, and radiological correlations.Methods.Forty-eight subjects with a history of gouty arthritis (American College of Rheumatology criteria) for ≥ 3 years under poor control were included. Subjects underwent history, physical examination, laboratory testing, and imaging studies, including radiographs of the hands and feet and computerized tomography (CT) of the cervical and lumbar spines and sacroiliac joints (SIJ). Patients with characteristic erosions and/or tophi in the spine or SIJ were considered to have axial or spinal gout.Results.Seventeen patients (35%) had CT evidence of spinal erosions and/or tophi, with tophi identified in 7 of the 48 subjects (15%). The spinal location of axial gout was cervical in 7 patients (15%), lumbar in 16 (94%), SIJ in 1 (6%), and more than 1 location in 14 (82%). Duration of gout, presence of back pain, and serum uric acid levels did not correlate with axial gout. Extremity radiographs characteristic of gouty arthropathy found in 21 patients (45%) were strongly correlated with CT evidence of axial gout (p < 0.001). All patients with tophi in the spine had abnormal hand or feet radiographs (p = 0.005).Conclusion.Axial gout may be a common feature of chronic gouty arthritis. The lack of correlation with back pain, the infrequent use of CT imaging in patients with back pain, and the lack of recognition of the problem of spinal involvement in gouty arthritis suggest that this diagnosis is often missed.
Peptidylarginine Deiminase Type 4 and Methyl-CpG Binding Domain 4 Polymorphisms in Chinese Patients with Rheumatoid Arthritis
Authors: CHENG JINLUO , ZHANG HUI , ZHUANG CHAO , LIU RUIPING 
Published: April 2012

Objective.Peptidylarginine deiminase type 4 (PADI4) and methyl-CpG binding domain 4 (MBD4) are closely related with rheumatoid arthritis (RA). We hypothesized that PADI4 and MBD4 polymorphisms may contribute to RA susceptibility.Methods.We studied PADI4 rs2240340 G/A, PADI4 rs874881 C/G, MBD4 rs140693 G/A, and MBD4 rs2005618 T/C gene polymorphisms in 329 patients with RA and 697 controls in a Chinese population. Genotyping was done using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).Results.When the PADI4 rs2240340 GG homozygote genotype was used as the reference group, the AA genotype was associated with a significantly increased risk of RA. In the recessive model, when PADI4 rs2240340 GG/GA genotypes were used as the reference group, the AA homozygote genotype was associated with a significant increased susceptibility to RA. PADI4 rs874881 C/G was in complete linkage disequilibrium with PADI4 rs2240340 G/A. MBD4 rs140693 G/A and MBD4 rs2005618 T/C polymorphisms were not associated with the risk of RA. In stratification analyses, a significantly increased risk for RA associated with the PADI4 rs2240340 AA genotype was evident among older patients and patients who were anticitrullinated protein antibody (ACPA)-positive compared with the PADI4 rs2240340 GG/GA genotype.Conclusion.These findings suggest that the functional single-nucleotide polymorphism PADI4 rs2240340 G/A variant allele is associated with RA development, especially among older patients and ACPA-positive patients. However, our results were obtained from a moderate-sized sample, and therefore this is a preliminary conclusion. Validation by a larger study from a more diverse ethnic population is needed to confirm these findings.
Certification Of Occupational Therapists in the Public Schools: The Wisconsin Experience
Authors: Punwar Alice , Wendt Eugene 
Published: April 2012

Abstract
The history of public school certification for occupational and physical therapists is reviewed. The process used to develop the current standards for certification of public school occupational therapists in Wisconsin and the standards that resulted are described. The implications of school certification requirements are discussed in terms of basic professional education in occupational therapy, and recommendations are made regarding the establishment of certification standards for school-based therapists.
Single Subject Research in Occupational Therapy: A Case Illustration
Authors: Madsen Paula S. , Conte Jon R. 
Published: April 2012

Abstract
Three male children with behavior-disorders were treated by tactile, vestibular, and proprioceptive sensory stimulation in 20-minute sessions 3 times per week for a period ranging from 4-to-6 weeks. Attention to a mathematical computation task was measured for several sessions before the introduction of treatment and immediately after each treatment session. Attention was operationally defined as the total time spent attending to the task during a ten minute test period.
Of the three subjects, one showed negligible change, one showed some performance improvement and a reduction in response variability, and the third showed improvement followed by performance deterioration, though not to original low baseline levels.
Although improvements were coincident with the onset of treatment, they may not be attributed to it, because no response stability was achieved during the baseline condition.
Patterns of Static Prehension in Normal Hands
Authors: Kamakura Noriko , Matsuo Michiko , Ishii Harumi , Mitsuboshi Fumiko , Miura Yoriko 
Published: April 2012

Abstract
According to the finger positions and the contact areas, the static prehensile patterns of normal hands were classified into 14 patterns under 4 categories. The patterns that 7 subjects used for holding each of 98 objects were confirmed under these new classifications. The findings could be of reference value for the therapist interested in the evaluation and the re-education of disabled hands.
Normative Comparison of the Southern California Postrotary Nystagmus Test: Los Angeles vs. Syracuse Data
Authors: Kimball Judith Giencke 
Published: April 2012

Abstract
A normative comparison was carried out on the Southern California Postrotary Nystagmus Test. Two hundred and twenty two (222) children, ages five to nine, from Syracuse, New York, were compared with the original Los Angeles sample of 226. In analyzing the Syracuse data, no significant differences were found in duration of postrotary nystagmus by age, sex, or age/sex interaction. Comparison of the Syracuse with the Los Angeles data revealed significantly different means and standard deviations, with the effect that the cut-off point for diagnosing prolonged nystagmus shifted upward. It was concluded that postrotary nystagmus is a consistent measure unaffected by age or six in normal five- to nine-year-olds, but that in view of the differences between the Syracuse and Los Angeles data, care should be taken in diagnosing prolonged postrotary nystagmus.
Gaming Technique: An Assessment and Training Tool for Individuals with Learning Deficits
Authors: Hurff Janith McCready 
Published: April 2012

Abstract
In this article the literature on gaming technique is reviewed as applied to life simulation experiences. The gaming technique is the use or the adaptation of existing games or the development of training games. Training games are useful educational tools to teach daily living skills to the mild to moderate mentally retarded population and other individuals with learning deficits. The author discusses the application of games to a variety of training situations in the occupational therapy clinic and summarizes techniques for making an adaptation of or for constructing games. Four games are included: a pegboard game, a friendship or socialization game, a money-calculator game, and a disaster game.
A Study of Reliability and Validity of a Preschool Play Scale
Authors: Bledsoe Nancy Parry , Shepherd Jayne T. 
Published: April 2012

Abstract
Childhood play is a major arena for development of knowledge, skills, and attitudes that permit productive adult behavior. Occupational therapists must assess and treat play dysfunctions in order to promote normal development. The purpose of this study was to examine the reliability and validity of a play assessment tool, the Preschool Play Scale. Ninety children were observed and rated on the Preschool Play Scale, Lunzer’s Scale of Organization of Play Behavior, and Parten’s Social Play Hierarchy. Data were analyzed using bivariate correlation coefficients. Significant results suggest that the Preschool Play Scale will yield objective, stable, and valid measurements of play for normal preschool children when administered by trained observers. Recommendations for further study of the Preschool Play Scale are given.
A Transdisciplinary Mobile Intervention Program for Rural Areas
Authors: Magrun W. Michael , Tigges Kent Nelson 
Published: April 2012

Abstract
A critical priority in allied health today is the efficient delivery of comprehensive services with the family and professionals as equal partners. In rural areas this is particularly important because of sparsely located populations and limited distribution of services. Few facilities in the rural community are able to deliver comprehensive services to a wide geographical area. Location of the services also presents additional burdens on the rural family with a developmentally disabled child. In this paper the stages of program development to meet a specific regional health need are described. The use and characteristics of a mobile program of early intervention serving developmentally disabled infants and preschoolers in rural areas of southwestern New York State are discussed. The practical application of this approach is considered.
Self-Catheterization Training of a Child with Myelomeningocele
Authors: Clarkson Jean Douglas 
Published: April 2012

Abstract
This paper describes how the occupational therapist, following a urologists’ orders, teaches clean intermittent self-catheterization as a self-care skill to handicapped school children when no trained enterostomal therapist is available. It contains a review of the literature, a definition of neurogenic bladder types, a description of intermittent catheterization, and the steps involved in teaching the technique to children. A case study is given that shows the training of a child with myelomeningocele to catheterize herself, and the therapist’s interaction with the school nurse and other members of the team.
Identification of Factors of Affective Meaning in Four Selected Activities
Authors: Nelson David L. , Thompson Gayle , Moore Jacquelyn A. 
Published: April 2012

Abstract
The premise that activities have inherent meanings is basic to the theory and practice of occupational therapy. In this study the investigators hypothesized that different activities would elicit different kinds of affective meanings in their participants. The subjects in this study were 59 students beginning their training in occupational therapy. On their first day in an activities class, and before instruction in activity analysis, the subjects were presented with four selected activities. Immediately after performing each activity, the students were requested to rate the activity according to Osgood’s 12-scale short-form semantic differential. The data generated were reduced subsequently to Osgood’s three factors of affective meaning: “evaluation,” “power,” and “activity” (in this study called action). Results indicated that the four activities elicited significantly different responses on all three factors. Specific results and implications of this study’s methodology for future occupational therapy research are discussed.
Quality Assurance Requirements of the Joint Commission on Accreditation of Hospitals
Authors: Ostrow Patricia Curran 
Published: April 2012

Abstract
In 1981, the Joint Commission on Accreditation of Hospitals instituted new quality assurance requirements. As occupational therapy departments plan for accreditation review, they must address these changes, which are markedly different from earlier standards. This article outlines the essentials. Official interpretations of the Joint Commission’s quality assurance standard and its application to occupational therapy are presented. The focus of this paper is on one possible quality assurance system. The elements of an effective quality assurance plan for an occupational therapy department are defined, and a hypothetical quarterly report for a department is presented. The ongoing review and evaluation monitors required by the Joint Commission are described.
The Effect of Psychological Type on the Mood and Meaning of Two Collage Activities
Authors: Carter Barbara A. , Nelson David L. , Duncombe Linda W. 
Published: April 2012

Abstract
This study used the Myers-Briggs Type Indicator to identify two types of college students who differed in preferred perceptual processes, with one group strongly preferring the use of sense impressions (sensing types), and the other preferring the use of unconscious associations (intuitive types) in becoming aware of phenomena. All subjects then participated in two collage activities with slightly different instructions, one requiring a creative approach and the other requiring imitation. Change in mood after each collage was measured by the Bipolar Form of the Profile of Mood States, and the affective meanings of the two activities were assessed by Osgood’s 12-scale short-form semantic differential. Results indicated that the creative activity elicited significantly higher scores on two mood states (agreeable-hostile and composed-anxious) and two factors of affective meaning (power and evaluation). Intuitive types rated both activities higher than sensing types on one mood (agreeable-hostile) and one factor of affective meaning (action). Hypothesized interactions were not found. The findings have possible implications for the effects of occupational therapy activities that require creativity as opposed to imitation as well as for the effects of perceptual preferences on the moods and meanings of activities.
Examining the Reliability and Validity of the Play History
Authors: Behnke Cindy Jill , Menarchek Fetkovich Marilee 
Published: April 2012

Abstract
Few occupational therapy tools exist that evaluate play totally and systematically. The purpose of this study was to examine the Play History Interview and establish its value as a scientific clinical tool. The parents of 15 disabled and 15 nondisabled children between the ages of 1 and 7½ years were interviewed about their children’s play behaviors using the Play History Interview. Children were rated on an ordinal scale according to the criteria outlined on the Play History Chart and Taxonomy for Diagnosis. Interrater and test-retest reliabilities were determined by two independent raters. The scores from the Play History and Minnesota Child Development Inventory were correlated to examine concurrent validity of the Play History. Content validity was studied via a literature review. Significant results suggest that the Play History is a reliable and valid interview in occupational therapy for assessing children’s play behavior.
Splint Modification for Flexor Tendon Repairs
Authors: Lopez Mary Sullivan , Hanley Kevin F. 
Published: April 2012

Abstract
A modification of the Kleinert orthosis providing early controlled mobilization following flexor tendon repair is presented in the article. Ongoing evaluations of the efficacy of the splint are described and implications for use in treatment are reviewed.
The views expressed in this paper are those of the authors and do not reflect official United States Army or U.S. Department of Defense Policy.
Occupational Therapy Management and Job Performance of Staff
Authors: Brollier Chestina 
Published: April 2012

Abstract
This study focuses on two basic research questions: 1. Do discrepancies exist between the way hospital-based occupational therapy department directors perceive their managerial leadership and the way their occupational therapy staff members perceive the directors’ leadership? 2. What effect does the managerial leadership of the directors have on staff occupational therapists’ job performance? Mailed questionnaires were completed by 93 occupational therapy directors and 348 nonmanagerial registered occupational therapists who were employed in hospitals throughout the continental United States.
The directors and their staff members demonstrated significant differences in their assessments of the directors’ managerial leadership styles; directors generally gave themselves higher ratings than did their staff members. The occupational therapy directors gave their staff high job performance ratings. Also, discrepancies between the directors’ and their staff occupational therapists’ ratings of the directors’ leadership styles correlated negatively with staff job performance. The results of the study suggest some potentially beneficial management training topics for department directors.
Sensory Intervention With the Preterm Infant in the Neonatal Intensive Care Unit
Authors: Anderson Jill 
Published: April 2012

Abstract
Sensory intervention, one aspect in the occupational therapy treatment of the high-risk, preterm infant in the neonatal intensive care unit (NICU), is discussed. Normal deviations in the healthy preterm baby’s development at the equivalent age of the full-term baby are identified as a basis for intervention. Environmental factors affecting the preterm infant’s interactions and therapeutic needs, such as the NICU environment and medical intervention, are reviewed. The rationale underlying the selection of sensory evaluation and treatment approaches is based on recent research. These approaches primarily focus on visual, tactile, proprioceptive, vestibular, and, to a lesser degree, auditory stimulation.
Splinting Proximal Interphalangeal Joint Flexion Contractures: A New Design
Authors: Callahan Anne D. , McEntee Pamela 
Published: April 2012

Abstract
Proximal interphalangeal joint flexion contracture is a common and persistent problem in hand rehabilitation. This article discusses the advantages and disadvantages of several current splint designs for correcting this contracture and introduces an alternate design that uses wire in a 3-point pressure system. The advantages of this design include ease of fabrication, patient appeal, and effectiveness.
The Efficacy of the ROM Dance Program for Adults With Rheumatoid Arthritis
Authors: Van Deusen Julia , Harlowe Diane 
Published: April 2012

Abstract
This study examined the efficacy of an exercise and relaxation program for adults with rheumatoid arthritis. The program integrates principles of occupational therapy and T’ai-Chi Ch’uan and was expected to be more effective than traditional exercise and rest regimens because of its expressive and pleasurable elements. There were significant differences between 17 experimental and 16 control subjects on two categories of dependent variables after the former group’s participation in the experimental program. These dependent variables were range of motion measures and subject self-reports of frequency, enjoyment, and benefits of home exercise and rest routines. Pretest, posttest, and 4-month follow-up data were analyzed.
Program participants showed significantly greater upper extremity range of motion 4 months after completing the program although the reported frequency of exercise and rest was greater in the control group. Postprogram reports of enjoyment were significantly higher for experimental than for control subjects. If these initial results are confirmed in further studies, the efficacy of the use of purposeful activity for exercise and rest will be supported. This study also supports the integration of Eastern and Western frames of reference in the treatment of patients with chronic illness.
Bilateral Hand Performance With Divided Attention After a Cerebral Vascular Accident
Authors: Dittmar Christy M. , Gliner Jeffrey A. 
Published: April 2012

Abstract
A divided attention task was used with 10 left or right cerebral vascular accident (CVA) subjects who had return of functional movement in the affected extremities. The primary task was one subtest of the Jebson Hand Function Test. The secondary task was a foot press to a series of auditory cues. Four measurements were obtained for each subject at intervals of 1 month, 2 months, and 3 months after the stroke. Comparison scores on this procedure were also obtained on 5 normal subjects.
The results indicated that dividing attention in the CVA subjects significantly decreased the performance on the primary task. The performance with the affected limb improved over the 3-month time period and reached a level of performance that was not significantly different from that of the unaffected limb for either the undivided or divided attention task. Implications for occupational therapy environments and consideration of attention limitations are discussed.
Behavioral Treatment of Attention Deficits in Mentally Impaired Subjects
Authors: Burgess Paul W. , Mitchelmore Stuart , Giles Gordon M. 
Published: April 2012

Abstract
This paper describes an operant approach to the remediation of the behavioral aspects of attention deficits in three mentally impaired subjects. Two of the subjects also displayed severe atypical psychiatric disorders. Contingent reinforcement within an ABAC experimental design was used to increase levels of attending behavior. The efficacy of this approach within a group setting was demonstrated. Results suggest that some forms of additional deficit may be treated behaviorally despite differing etiologies of the cognitive deficit. The implications for occupational therapy are discussed within the context of the design of the ward program.