bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of accidents in maritime transport using the method of Bayesian trust networks
Authors: Popov Anatoly N. , Zelenkov Gennadiy A. , Pluzhnik Valeriy S. , Borodin Oleg E. 
Published: June 2024

Maritime incidents, though rare, have a significant impact on both the global economy and the environment. Improving maritime navigation practices always requires new ways to enhance safety, inevitably involving learning from past experiences and mistakes. In this context, probabilistic analysis of incidents and their associated consequences can play a crucial role in creating a safer and more efficient maritime transportation system. Bayesian networks constitute a class of probabilistic models based on statistics, decision theory, and graph theory.
This paper describes the analysis of maritime incident statistics by selecting probabilistic parameters influencing the risk of their occurrence. Important parameters from this database are grouped, and a Bayesian network is constructed to illustrate the relationships between them. This, in turn, provides insight into the dependencies existing among the variables in the database and the fundamental reasons for these accidents. The data for this study are based on the Lloyds Register and IMO incident databases from 1990 to 2022. Key factors from this database are grouped, and a Bayesian network is built to show the relationships between the corresponding variables, providing an understanding of the probabilistic dependencies among the variables in the database and the primary causes of these incidents.
Formation of a Magnetic Cloud from the Merging of Two Successive Coronal Mass Ejections
Authors: Chen Chong , Liu Ying D. , Zhu Bei , Hu Huidong , Wang Rui 
Published: June 2024

Abstract
On 2022 March 28 two successive coronal mass ejections (CMEs) were observed by multiple spacecraft and resulted in a magnetic cloud (MC) at 1 au. We investigate the propagation and interaction properties of the two CMEs correlated with the MC using coordinated multipoint remote sensing and in situ observations from Solar Orbiter, STEREO-A, Solar and Heliospheric Observatory, and Wind. The first CME was triggered by a filament eruption with a high inclination angle. Roughly 9 hr later, the second CME originating from the same active region erupted with a smaller tilt angle and faster speed compared to the first one. The second CME overtook the preceding CME and formed a merged front at approximately 75 R
☉, which developed into a complex ejecta at 1 au. The descending speed and low proton temperature inside the complex ejecta suggest that the two CMEs have fully merged before reaching 1 au, leading them to begin expanding rather than compressing against each other. The complex ejecta appears to have the magnetic field and plasma signatures of an MC, although there is a discontinuity in the magnetic field implying previous interactions. The cross section of the complex ejecta, reconstructed from in situ data using a Grad–Shafranov technique, exhibits a right-handed flux rope structure. These results highlight that an MC-like complex ejecta lacking interaction features could arise from the complete merging of two CMEs.
Les Indications Géographiques pour les Productions Industrielles et Artisanales : la révélation d’un ancrage industriel territorialisé ?
Authors: Baujard Baptiste , Dedeire Marc 
Published: June 2024

Les Indications Géographiques pour les Productions industrielles et artisanales (IGPIA), créées à l’initiative de la loi Consommation de 2014 (loi Hamon), se sont révélées être des outils particulièrement efficaces pour la protection des savoir-faire et le rayonnement de ces différentes productions industrielles et artisanales, à l’échelle nationale comme internationale dans le cadre d’une réindustrialisation de plus en plus accentuée de nos territoires.L’ancrage des entreprises pour ce type de production se doit donc d’être fort. Ce papier tente de révéler l’ancrage industriel de ses productions depuis un point de vue géographique géographie économique en essayant de mesurer leurs ancrages afin de s’interroger sur la révélation de ces ancrages industriels au sein de leurs territoires respectifs.Classification JEL : L6, R0, R12.
La construction politique de la diversification économique régionale : une comparaison de filières en Bretagne et au Québec maritime
Authors: Police Antoine 
Published: June 2024

La diversification des économies régionales constitue un letimotiv ancien des politiques de développement régional et suscite un intérêt renouvelé des géographes et économistes dans le milieu académique. Ce papier développe une approche politique de la diversification en montrant que les acteurs sociaux sont susceptibles de générer collectivement, à partir d’une même activité et dans une même région, des projets de diversification à géométrie variable sur un mode plus ou moins conflictuel. Les bifurcations dans une trajectoires de diversification sont expliquées à l’aune des dynamiques du travail politique (cadrage, instrumentation et alliance) opéré par les acteurs qui jouent avec les opportunités offertes par leur contexte institutionnel (sectoriel et territorial). Ces propositions théoriques sont testées à partir de la comparaison de deux branches émergentes de l’aquaculture en région maritime périphérique (Bretagne, Québec Maritime).Classification JEL : D78 – L78 – O13 - O25.
Lyon, aménager la métropole industrielle
Authors: Lejoux Patricia , Linossier Rachel 
Published: June 2024

Cet article vise à apporter de nouveaux éléments de connaissances sur la dimension institutionnelle des effets locaux de la performance économique des territoires. Il cherche plus particulièrement à comprendre le rôle que peuvent jouer les collectivités locales, en l’occurrence les métropoles, dans le dynamisme industriel de leur territoire. Il analyse pour cela les politiques d’aménagement et d’urbanisme menées par la Métropole de Lyon pour mettre en œuvre sa politique industrielle. Les résultats montrent que la mise en œuvre de cette politique industrielle est facilitée par l’alignement des acteurs de l’écosystème territorial, la mobilisation de différents leviers d’action spatiale (urbanisme réglementaire, politique foncière et immobilière, etc.) et la prise en compte de la diversité des problématiques industrielles et urbaines au sein de la métropole. Mais elle se heurte à la difficulté de concilier politique de développement économique, politique d’aménagement urbain et politique de mobilité à l’échelle d’une métropole.Classification JEL : L52, L60, R30, R52.
Territoires d’industrie : hétérogénéité et convergence
Authors: Amdaoud Mounir , Levratto Nadine 
Published: June 2024

L’objectif de cet article est d’explorer la nature des dynamiques de l’emploi dans les territoires d’industrie en France sur la période 2014 à 2021. Deux méthodes d’investigation complémentaires sont déployées. La première s’appuie sur le modèle des chaînes de Markov en vue d’analyser la croissance relative des territoires d’industrie et mesurer les mouvements dans la distribution des taux d’emploi. La seconde, plus récente, teste l’hypothèse de convergence en clubs, elle complète la précédente en précisant et identifiant chacun des territoires faisant l’objet d’une mobilité au sein de la distribution. Les résultats mettent en avant l’hétérogénéité des processus de croissance et de convergence des territoires d’industrie ainsi que l’absence d’une trappe à industrie.Classification JEL : R11, C14, O42, R15.
DEL phenotype in RhD-negative North Indian blood donors
Authors: Kaur Paramjit , Bedi Ravneet K. , Sood Tanvi , Mittal Kshitija , Kaur Gagandeep 
Published: June 2024

Abstract:

BACKGROUND:
Rh-DEL type is not detected on routine serology and requires specialized adsorption elution methods which are laborious. Identifying the DEL phenotype in blood donors is important to prevent alloimmunization in transfusion recipients. The present study aimed to determine the frequency of DEL phenotype in RhD-negative North Indian blood donors and correlate the results with Rh Cc/Ee phenotype.

MATERIALS AND METHODS:
In this prospective descriptive cross-sectional study, a total of 205 blood donors with historic blood group RhD-negative were enrolled. All samples were subjected to blood grouping using a fully automated immunohematology analyzer and samples that typed as RhD negative by two different anti-D antisera were tested for Weak D. Weak D-negative samples were subjected to adsorption and elution for DEL phenotype. All samples were also tested for extended Rh phenotype for C/c and E/e antigens.

RESULTS:
Of the total 11934 donors during the study, 6.2% (n = 743) donors were RhD negative. Of the 205 donors enrolled in the study, two donor samples were serologically weak D positive. None of the remaining 203 donors tested positive for the DEL phenotype. The extended Rh phenotype performed for these donors showed that 6.83% (n = 14) donors were positive for RhC antigen and 1.46% (n = 3) were positive for Rh E antigen. Both weak D-positive donors were also positive for the Rh C antigen.

CONCLUSION:
The prevalence of DEL phenotype is low in the Indian population and studies with larger sample sizes are required to determine the effectiveness of routine C/E typing as a strategy to identify DEL-positive individuals.
Audit-based corrective and preventive actions to reduce wastage of blood components at a single blood center: A quality improvement study
Authors: Gnanaraj John , Kulkarni Rajendra , Sahoo Dibyajyoti , Basavarajegowda Abhishekh 
Published: June 2024

Abstract:

INTRODUCTION:
The rate of discarded blood components or “wastage rate” reflects on the whole process, preparation, and production of blood and its quality control. It is the ratio of blood and blood components discarded to the total number of collections. The discard or unusability of blood products are many, and the ones that can be monitored and regarded as indicators to be improvised on are QC failure rate, transfusion-transmitted infection (TTI) positivity, and component discards (other than TTI), including those that caused transfusion reactions. These were studied over four intervention cycles to see if they could be improved.

MATERIALS AND METHODS:
This was a clinical audit and quality improvement study. The clinical audit was conducted over four cycles over 16 months. Each cycle included three stages wherein the data required for calculating those key performance indicators (KPIs) of the blood center were studied and analyzed, and causes for the poorly performing ones were identified; a corrective plan was drawn and implemented, followed by data collection and interpretation of the same in the next cycle for improvement. The data were compiled using a Microsoft Excel spreadsheet and analyzed using SPSS version 19 (IBM Corporation, New York, USA).

RESULTS:
The overall discard rates due to all cumulative causes mentioned were at about 5% at the start of the first cycle. The various factors comprising preparatory, preparation, and the management of inventory and issue were analyzed, and corrective interventions were performed in every cycle. The discard rates were reduced to about 3% by the end of the four cycles. The difference was statistically significant, with a P < 0.05.

CONCLUSION:
The implementation of Corrective and preventive action measures can rectify the deviations in KPIs. The blood center director, staff, and doctors should be responsible for maintaining and continuously improving the quality indicators.
Hemovigilance data: An effective approach for evaluating bacterial protection systems for platelet transfusions
Authors: Alabdullatif Meshari I. 
Published: June 2024

Abstract:

BACKGROUND AND OBJECTIVE:
Septic transfusion reactions due to bacterial contamination in platelet concentrates (PCs) are continually reported to hemovigilance (HV) programs. Worldwide, blood centers use different systems to avoid transfusion-associated bacterial sepsis in PCs. Herein, national HV data were gathered to compare bacterial protection systems and to assess the risk of bacterial contamination.

MATERIALS AND METHODS:
HV data with definite transfusion-associated bacterial sepsis in PCs were obtained from Australia, Canada, the United Kingdom (U. K.), and Switzerland between 2006 and 2016. These data were reviewed to evaluate bacterial protection systems including early small-volume (ESV), early large-volume (ELV), and delayed large-volume (DLV) bacterial culture screening and pathogen inactivation (PI) treatment.

RESULTS:
Implementation of DLV bacterial culture screening in the U. K. and PI treatment in Switzerland resulted in significant reductions (P < 0.05) in transfusion-associated bacterial sepsis for the period of 2011–2016 compared to the prior 4 years (2006–2010). Approximately 1.86 million DLV bacterial culture-screened PCs and 0.21 million PI-treated PCs were issued with no reported septic fatalities nor cases of life-threatening sepsis. In Australia, two life-threatening septic transfusion reactions (1.923 per million) were reported out of almost 1.04 million ELV bacterial culture-screened PCs, and no septic fatalities were reported. Meanwhile, in Canada, four life-threatening septic transfusion reactions (3.6/million) and one fatality (0.9/million) were observed in about 1.11 million ESV bacterial culture-screened PCs.

CONCLUSION:
DLV bacterial culture and PI treatment significantly reduced the incidence of septic reactions. The advantages and disadvantages of both systems merit further investigation before implementation.
Aweak phenotype associated with novel ABO*A allele variant c.106delinsGG
Authors: Joshi Sanmukh Ratilal , Millard Glenda , Vekariya Mayuri , Radadiya Priya , Rajapara Manisha , Dhanani Hiren , Shastri Gaurav , Sharma Prabhat , Wilson Brett , Liew Yew-Wah 
Published: June 2024

Abstract:

BACKGROUND AND OBJECTIVES:
Discrepancy between forward and reverse ABO grouping could be due to several reasons including genetic mutations of the alleles encoding group specific transferase. The healthy donors found with weak A antigen were investigated to ascertain the allele responsible for variation.

MATERIALS AND METHODS:
Standard serological methods were employed using commercial antisera. The molecular sequencing was performed on DNA with enrichment library prep kit and a custom designed overlapping probe panel. Binary alignment mapping files, generated on board the Illumina MiSeq instrument and aligned to the GRCh37/Hg19 reference genome, were uploaded to the QIAGEN CLC genomics workbench software (version. 20) where variant call files were generated and analyzed.

RESULTS:
Red blood cells (RBCs) of six healthy donors, showing weak mix-field agglutination by anti-A and anti-A, B and plasma with absence or weakly reacting anti-A, were investigated serologically. The RBCs incubated with anti-A yield positive elution and their saliva lacked A but possessed H antigen thereby classifying as a historical known phenotype Aend. Family study on 4 probands showed inheritance of the trait. Molecular studies revealed presence of ABO*A allele carrying rare novel variant referred to as c.106delinsGG in line with HGVS recommendation that was thought to be responsible for the variant of A.

CONCLUSION:
Six cases serologically defined as Aweak were found to be associated with novel allele ABO*A (c.106delinsGG). The Aweak phenotype with the novel allele has not been displayed on International Society of Blood Transfusion database, though c.106delinsGG is listed in the UCSC genome browser under rs782544248.
Tailoring transfusion strategy using thromboelastogram in goal-directed massive transfusion: Impact on transfusion requirements and clinical outcomes
Authors: Prethika P. A. , Mohan Ganesh , Shastry Shamee , Balakrishnan Jayaraj Mymbilly 
Published: June 2024

Abstract:

BACKGROUND AND OBJECTIVE:
We compared the overall clinical outcome in formula-based protocol (1:1:1) and thromboelastogram (TEG)-guided goal-based massive transfusion (MT) in the resuscitation of patients with hemorrhagic shock.

MATERIALS AND METHODS:
This was a retro-prospective case–control study conducted over a period of 2 years among the patients who received MT using a 1:1:1 fixed ratio protocol (controls, Group A) and goal-based protocol (cases, Group B) guided through TEG. Patients were matched for the type and severity of the clinical conditions. Utilization of blood components, clinical outcomes, transfusion-related complications, and total mortality rates were compared between the groups.

RESULTS:
There were 113 patients in the formula-based group and 109 patients in the goal-based transfusion group who were matched for injury severity scores. The total blood components utilized were 1867 and 1560, respectively, with a 17.7% reduction associated with the use of TEG. Patients were divided into normal, hypo, and hypercoagulable based on TEG, and a higher transfusion rate was associated with hypocoagulable TEG (942 vs. 610). The prothrombin time, activated partial thromboplastin time, R time, and K time had a significant positive correlation with the need to transfuse more than 20 blood components, whereas platelet count, base excess, alpha angle, MA, and CI had a negative correlation (r = 0.268, P < 0.001). At the end of goal-directed transfusion, 75% of the patients were free of transfusion support (vs. 65.4%) and only 6.9% of the patients had coagulopathy (vs. 31.8%) compared to formula-based resuscitation with a 10% reduction in mortality.

CONCLUSION:
TEG-guided goal-based approach helped to reduce blood component utilization with a reduced incidence of coagulopathy at the end of the MT while improving patient survival.
Efficacy of Urinary Diversion in Gynecological Cases: A Retrospective Study at a Tertiary Referral Hospital
Authors: Azmi Rizza Maulana , Azmi Yufi Aulia , Tjokroprawiro Brahmana Askandar , Yadav Deepak Kumar , Khadga Ajit 
Published: June 2024

ABSTRACT

Introduction:
Gynecological malignancies are one of the most common cancers in women. Morbidity, in this case, can occur in patients with advanced cancer, and one of the causes is hydronephrosis. In the development of this case, a double-J stent (DJS) is usually used to treat urinary diversion. This research aimed to analyze the comparison of hydronephrosis patients from gynecologic oncology treated with DJS and without DJS.

Methods:
Retrospective research was conducted by reviewing 115 medical record data. Patients with hydronephrosis related to gynecologic oncology at a referral hospital in Surabaya, Indonesia, from January to August 2023 were included in this study. Data were analyzed using the Chi-square test for categorical data. For numerical data, they were analyzed using the Mann–Whitney test.

Results:
Cervical cancer was found in almost half of the total patients. Most patients undergo a DJS procedure. Nearly half of the patients experienced moderate category hydronephrosis before treatment and mild category after treatment. More than half of patients experience hydronephrosis on one side. The statistical test results of patients who underwent DJS installation and those who were not installed with DJS regarding the length of treatment (length of stay), prediversion creatinine, postdiversion creatinine, cancer stage, side of hydronephrosis, and length of operation showed P < 0.05.

Conclusions:
The use of urinary diversion in cases of gynecological malignancies can support the management of hydronephrosis in gynecological cancer patients. There are differences between patients who undergo DJS installation and those who do not undergo DJS installation, which show specific indications.
Functional Outcome of Acetabular Fracture Using Majeed Score: A Single-center Retrospective Study
Authors: Soetjahjo Bintang , Adriansyah Denny , Malik Ricat Hinaywan , Munoz Michael Del Rosario 
Published: June 2024

ABSTRACT

Introduction:
Acetabular fractures make a challenge for orthopedic trauma surgeons. The published data on acetabular fracture in Indonesia are very limited and there is no study to assess the functional outcome of acetabular fracture using the Majeed score. This study aims to report the functional outcome of an acetabular fracture using the Majeed score in one tertiary referral hospital (single center), Dr. Moewardi General Hospital.

Methods:
This is a retrospective descriptive study with a cross-sectional design from patients who registered on January 1, 2017–December 31, 2021 (5 years) at Dr. Moewardi General Hospital, a referral Hospital in Surakarta, Indonesia. The inclusion criteria included all acetabular fracture patients who registered and had complete data.

Results:
The most common type of acetabular fracture based on Judet-Letournel classification in this study is both columns (59.1%), most commonly treated by surgery. The most common surgical approach to treating an acetabular fracture is the anterior approach. The Majeed score shows the total of good and excellent outcomes after surgery (57.2%) is higher than fair and poor outcomes (42.9%), and the total of good and excellent outcomes after nonsurgical treatment (66.7%) is higher than fair and poor outcomes (33.3%).

Conclusion:
Using the Majeed score in a single center, the functional outcomes of acetabular fracture patients treated both surgically and conservatively are good to excellent.
Emerging Coproduction of AmpC Beta-lactamase in Extended-spectrum Beta-lactamase-producing Escherichia coli Clinical Isolates in Indonesia
Authors: Marzah Mohammad Agung , Sarassari Rosantia , Safari Dodi , Maladan Yustinus , Setyarini Wahyu , Sulistya Hanif Ardiansyah , Endraswari Pepy Dwi , Shirakawa Toshiro , Hirai Itaru , Kuntaman Kuntaman , Koendhori Eko Budi 
Published: June 2024

ABSTRACT

Introduction:
Extended-spectrum beta-lactamase (ESBL) and AmpC beta-lactamase (AmpC-BL) in Enterobacteriaceae are a global threat. Coproduction of AmpC-BL and ESBL reduces therapeutic options, with more resistance against cephamycin and beta-lactamase inhibitor combinations. This study determines the proportion, incidence, and distribution of AmpC-BL-resistant genes in clinically isolated ESBL-producing Escherichia coli, completing its scarce data in Indonesia.

Methods:
The samples in this study were ESBL-producing E. coli from blood and urine specimens, confirmed by BD Phoenix semiautomatic examination combined with cefoxitin disk screening method. Confirmation tests of AmpC-BL used the AmpC-disk method and the polymerase chain reaction method.

Results:
Thirteen (27.8%) of 108 E. coli isolates were nonsusceptible to cefoxitin, and 3 (11.5%) isolates were confirmed to produce AmpC-BL and contained AmpC-BL CITM gene. Of the 3 AmpC-BL and ESBL coproduction isolates, one isolate was a copresentation of ESBL and AmpC-BL genes, namely blaTEM and CITM. Fisher’s exact test showed that the coproduction of AmpC-BL in ESBL-producing isolates was associated with reduced susceptibility to cefoxitin (P = 0.020) and amoxicillin-clavulanate (P = 0.048) compared to isolates producing ESBL alone. The effect of ESBL and AmpC-BL coproduction on reducing susceptibility to carbapenems needs further investigation.

Conclusions:
AmpC coproduction was found in 3 (2.8%) of 108 ESBL-producing E. coli isolates, and one isolate copresented AmpC-BL and ESBL coding genes blaTEM and CITM. These three isolates were associated with widened antibiotic resistance to cefoxitin and amoxicillin--clavulanate compared to isolates producing ESBL alone.