bluuebunny/crossref_metadata_2025_split huggingface dataset:
Das Bibliothekspraktikum „Studierende beraten Studierende“
Authors: Sobel Ariella 
Published: February 2025

Zusammenfassung
An der Fachbereichsbibliothek Bildungswissenschaft, Sprachwissenschaft und Vergleichende Literaturwissenschaft wird seit 2011 das Bibliothekspraktikum Studierende beraten Studierende angeboten. Dieses Praktikum ist curricular verankert und für Studierende mehrerer Studienrichtungen anrechenbar. Es besteht aus einer einführenden geblockten Lehrveranstaltung, gefolgt von einem 80-stündigen Praktikum an der Fachbereichsbibliothek. Im Anschluss an das Praktikum führen die Praktikant*innen selbst Bibliotheksführungen für Studienanfänger*innen durch.
In diesem Aufsatz werden Entstehung, Entwicklung, Konzept und Aufbau dieses besonderen bibliothekarischen Bildungsangebots und dessen Einbindung ins Curriculum erläutert.
Local Birkhoff decompositions for loop groups and a finiteness result
Authors: Patnaik Manish M. 
Published: February 2025

Abstract
Let

𝐆

{\mathbf{G}}

denote an affine Kac–Moody group, and G its points over the local field

𝔽
q

⁢

(

(
s
)

)

{\mathbb{F}_{q}((s))}

. We establish a local Birkhoff decomposition for a subset of G in terms of a pair of subgroups roughly of the form

𝐆
⁢

(

𝔽
q

⁢

[

[
s
]

]

)

{\mathbf{G}(\mathbb{F}_{q}[[s]])}

and

𝐆
⁢

(

𝔽
q

⁢

[

s

-
1

]

)

{\mathbf{G}(\mathbb{F}_{q}[s^{-1}])}

. Our techniques are global-to-local and use the reduction theory for loop groups due to H. Garland. Building on these ideas, we establish the finiteness of a set whose cardinality is related to spherical R-polynomials in D. Muthiah’s conjectural double-affine Kazhdan–Lusztig theory.
ЛЮДВИГ ВИТГЕНШТЕЙН И ГРЭМ ПРИСТ НА ПРЕДЕЛАХ МЫСЛИ
Authors: РОДИН К.А. 
Published: February 2025

В статье сформулированы предварительные критические замечания к предложенному Г. Пристом в контексте пределов выразимости на пределах мысли прочтению «Логико-философского трактата» Л. Витгенштейна и пониманию проблемы следования правилу. Во вводном и первом разделах кратко эксплицируется позиция Приста и приводятся предложенные Пристом и наши собственные примеры пределов выразимости. Во втором разделе сформулирована «доктрина» невыразимого в «Трактате» в контексте решительного и традиционного прочтения этого труда Витгенштейна. В последнем разделе высказаны критические замечания относительно релевантности прочтения Пристом Трактата и его понимания проблемы следования правилу.
The article formulates preliminary critical remarks on the reading of L. Wittgenstein’s Tractatus Logico-Philosophicus and understanding of the rule-following problem proposed by G. Priest in the context of the limits of expressibility at the limits of thought. In the introductory and first sections, we briefly explicate Priest’s position and provide examples of the limits of expressibility both proposed by Priest and our own. The second section formulates the “doctrine” of the inexpressible in the Tractatus in the context of a determined and traditional reading of this Wittgenstein’s work. In the last section, we offer criticism of the relevance of Priest’s reading of the Tractatus and his understanding of the rule-following problem.
Revised metal-silicate partitioning does not require the Late Veneer
Authors: Kondo Nozomi , Asanuma Hisashi , Yoshino Takashi 
Published: February 2025

Abstract

Highly siderophile elements (HSEs) are critical tracers for deciphering planetary formation and evolution. The widely accepted Late Veneer hypothesis, which proposes the accretion of chondritic materials after core formation, was developed to explain the discrepancy between metal-silicate partitioning behavior and the HSE composition of the Earth's primitive upper mantle (PUM). However, prior partitioning experiments relied on systems with unrealistically high bulk HSE concentrations, introducing significant uncertainty. Here, we present high-pressure and high-temperature experiments on HSE partitioning across a wide range of bulk HSE concentrations, including conditions relevant to terrestrial planets. Our results demonstrate that HSEs are more soluble in silicate melts at low concentrations and converge to chondritic relative abundances under these conditions, resolving the previous mismatch between mantle HSE composition and PUM. Furthermore, the revised partition coefficients not only reduce the discrepancy for Earth's mantle but also explain the HSE composition of the lunar mantle through core-mantle differentiation processes. These findings challenge the necessity of the Late Veneer for both Earth and Moon, aligning with recent discussions on the volatile element origins of terrestrial planets. This study offers a transformative perspective on the early differentiation and formation of Earth and other rocky planets in the solar system.
Polymer Matrix Drives Dual Phosphorescence in Dispersed Chromophores
Authors: Thilagar Pakkirisamy , Ghosh Subhajit Ghosh , Nandi Rajendra , Geremia Silvano , Hickey Neal , Sirohiwal Abhishek 
Published: February 2025

Abstract

Poly(methyl methacrylate) (PMMA) matrix has been extensively explored for decades to achieve efficient room-temperature phosphorescence in blue-to-red regions from dispersed chromophores. Isolated chromophores at low-weight concentrations in the polymer matrix eliminate the inter-chromophore interactions. However, the impact of the polymer matrix on the optical characteristics of chromophores remains elusive. Herein, we analyze the dual phosphorescence behavior of three chromophores molecularly dispersed (1 wt.% concentration) in the PMMA matrix. We employ second-order Algebraic Diagrammatic Construction (ADC2) excited state calculations to show that the dual phosphorescence observed in BANHPh and BANMePh does not stem from the T1 and T2 electronic states. Instead, this phenomenon arises from matrix-assisted, room-temperature accessible conformers within the T1 state (T1H and T1L). The PMMA matrix creates an asymmetric environment around the chromophores, inducing structural and electronic modulations that result in spectral tuning of the singlet and triplet manifolds. In conclusion, conformation-dependent dual phosphorescence is unlikely to occur without the PMMA matrix. These matrix-induced dual phosphorescent emitters have been demonstrated to be highly competent in the application of fingerprint recognition, information encryption, and afterglow display.
Exploring the Anticancer Potential of Epigallocatechin Gallate Loaded Sodium Alginate Nanoparticles: Impact of Size Variation on Head and Neck Cancer Cells
Authors: Rajabzadeh Faezeh , Arabhalvaei Mohadeseh , Arab Samaneh , Afraz Elham Sadat , Bahraminasab Marjan 
Published: February 2025

Abstract

Head and neck cancers, particularly squamous cell carcinomas, are challenging to treat due to recurrence, drug resistance, and side effects. The present study explores using epigallocatechin gallate (EGCG), an anti-cancer compound from green tea, encapsulated in sodium alginate nanoparticles (SA NPs) of varying sizes. Five different sizes of SA NPs were synthesized, and EGCG was loaded into the selected particles. Characterizations of SA NPs with and without EGCG were conducted using dynamic light scattering (DLS), FE-SEM, and Fourier transform infrared spectroscopy (FTIR). Furthermore, the loading capacity, entrapment efficiency and release profile of the EGCG-loaded NPs were evaluated. The cytotoxicity and cell viability were assessed using MTT and LDH assays on TSCC-1 cancer cells. Moreover, cellular uptake, wound healing, colony formation and apoptosis were also tested. The results of characterizations confirmed the successful synthesis of SA NPs. Two NP sizes (type 1 and type 4) were selected for EGCG loading, for which the drug release was around 39% for type 1 and 51% for type 4 nanoparticles after 14 days. The optimal cytotoxicity on cancer cells was observed at a concentration of 80 µg/mL of NPs (type 1). The colony formation analysis displayed a significant reduction in colony numbers after treatment with EGCG-loaded NPs compared to controls. Furthermore, wound healing assays showed the ability of EGCG-loaded NPs to prevent cancer cell migration, and the evaluation of apoptosis demonstrated an obvious increase in apoptosis levels in TSCC-1 cells treated with type 1 NPs (80 µg/mL). It was demonstrated that EGCG-loaded SA NPs effectively inhibit the proliferation and migration, and induce apoptosis in head and neck cancer cells.
Shock Reformation Induced by Ion-scale Whistler Waves in Quasi-perpendicular Bow Shock
Authors: Xu Sibo , Sun Jia-Ji , Wang Shan , Li Jing-Huan , Zhou Xu-Zhi , Graham Daniel B. , Hao Yu-Fei , Zong Qiu-Gang , Yue Chao , Omura Yoshiharu , Khotyaintsev Yuri V. 
Published: February 2025

Abstract

Studies have long suggested that shocks can undergo cyclical self-reformation as a type of shock nonstationarity. Until now, providing solid evidence for shock reformation in spacecraft observation and identifying its generating mechanisms remain challenging. In this work, by analyzing Magnetospheric Multiscale (MMS) spacecraft observations, we unambiguously identified shock reformation occurring in a quasi-perpendicular shock. A 2-D particle-in-cell simulation reproduces and explains the observed shock reformation. The simulation reveals that shock dynamics in the foot and ramp region generate two types of ion-scale whistler waves, respectively, each of which can drive shock reformation. Within one single wave period, the wave induces the magnetic field pile-up, ion accumulation and reflection, and upstream-pointing electric field, finally evolving into a new shock front. An interesting finding is that different shock dynamics compete and dominate the reformation at different stages. Our results not only provide evidence that the shock reformation in the present regime can be driven by ion-scale whistler waves, but also demonstrate the detailed kinetic processes how it happens, offering valuable insights into shock dynamics.
The valence states of Nb and Ta in magmatic-hydrothermal systems: Insights from combined SXAS and XPS analyses of titanite and ilmenite in two Chinese anorogenic suites
Authors: Zhu Yu-Xiang , Pan Yuanming , Wang Lian-Xun , She Zhenbing , Feng Renfei , Chen Ning , Purdy Sarah , Cao Kenan 
Published: February 2025

Abstract
Niobium and tantalum are the so-called “geochemical twins” with similar properties and have long been used to constrain magmatic sources and trace geological and planetary processes. Significant fractionations of Nb and Ta have recently been documented in diverse magmatic-hydrothermal and metamorphic systems, but their origin remains unclear. Niobium and Ta are preferentially incorporated in Ti-rich minerals such as ilmenite, rutile, and titanite. In this study, representative samples of Nb-rich titanite and ilmenite exhibiting large Nb/Ta variations (5 to 65) from two anorogenic alkaline suites in the Fangcheng and Ziyang regions of China and associated hydrothermal alteration have been investigated by Raman spectroscopy, synchrotron X-ray adsorption spectroscopy (SXAS) and X-ray photoelectron spectroscopy (XPS). The Raman spectra of Nb-rich titanite and ilmenite show only minor degrees of metamictization. The Nb K-edge SXAS spectra of Nb-rich ilmenite with Nb/Ta &gt; 30 are similar to that of Nb2O5, indicative of a dominant presence of Nb5+ with minor Nb4+, and an Nb5+/ΣNb ratio range from 0.59 to 1. In contrast, the Nb K-edge SXAS spectra of titanite and ilmenite with Nb/Ta &lt; 30 indicate mixed valences of Nb5+ and Nb4+, with Nb5+/ΣNb in the range of 0.22 to 0.55. Similarly, XPS measurements of titanite and ilmenite further support the presence of mixed valences of Nb, with Nb5+/ΣNb in the range of 0.49 to 0.85. In addition, Ta L3-edge SXAS spectra of titanite suggest the occupancy of Ta5+ at the octahedral site. Fitting results from Nb K-edge and Ta L3-edge extended X-ray adsorption fine structure (EXAFS) data further suggest that both Nb and Ta replace Ti via coupled substitutions of the type 2Ti4+ ↔ (Nb5+, Ta5+) + (Al, Fe)3+) and an isovalent substitution (Ti4+ ↔ Nb4+). A positive correlation between the oxidation states of Nb and the Nb/Ta values has been observed in titanite and ilmenite, but not for Ta. These results suggest that the extreme enrichment and large variations in Nb contents as well as significant fractionation of Nb from Ta in titanite and ilmenite are controlled by the prevailing oxygen fugacity in magmatic-hydrothermal systems. Given these complexities involving variable valence states, circumspection is required to use Nb and Ta anomalies to interpret geotectonic settings and apply Nb/Ta systematics to constrain magmatic-hydrothermal sources.
Investigation of LncRNA Expression Profiles and Analysis of Immune-Related lncRNA-miRNA-mRNA Networks in Neovascular Age-Related Macular Degeneration
Authors: Qin Liying , Gao Xiang , Lu Xiuhai , Liu Wencai , Tian Jingyi , Yuan Gongqiang 
Published: February 2025

Introduction:
Age-related Macular Degeneration (AMD) is a predominant cause of
blindness in the elderly. The present study is the first to investigate the alteration of lncRNAs
and mRNAs in neovascular AMD.

Methods:
Nine patients with neovascular AMD were included in the study. The control group
comprised seven patients with epiretinal membranes. RNA sequencing was performed to obtain
the differentially expressed mRNAs (DEmRNAs) and lncRNAs (DElncRNAs). Then, the
DElncRNA-DEmRNA co-expression network, ceRNA network, and immune-related ceRNA
subnetwork were constructed. Functional annotation of DEmRNAs between the two groups and
DEmRNAs in networks was conducted. The immune cell distribution in neovascular AMD was
also evaluated. Real-time qPCR (RT-qPCR) was used to validate the expression levels of key
markers.

Results:
A total of 342 DEmRNAs and 157 DElncRNAs were obtained in neovascular AMD.
Functional annotation indicated that these DEmRNAs significantly enriched immune systemrelated
processes, such as positive regulation of B cell activation, immunoglobulin receptor binding,
complement activation, and classical pathway. The DElncRNA-DEmRNA co-expression
network, including 185 DElncRNA-DEmRNA co-expression pairs, and the ceRNA
(DElncRNA-miRNA-DEmRNA) network, containing 45 lncRNA-miRNA pairs and 73 miRNAmRNA
pairs, were constructed. The immune-related ceRNA subnetwork, including 2 lncRNAs,
5 miRNAs, and 3 mRNAs, was constructed. In addition, the distribution of immune cells was
slightly different between the neovascular AMD group and the control group. RT-qPCR validation
indicated the consistency between the RT-qPCR results and RNA sequencing results.

Conclusion:
In conclusion, STC1, S100A1, MEG3, MEG3-hsa-miR-608-S100A1, and MEG3-
hsa-miR-130b-3p/hsa-miR-149-3p-STC1 may be related to the occurrence and development of
neovascular AMD.
Fabrication and Evaluation of Hyaluronic Acid Coated Albumin Nanoparticles for Delivery of Gemcitabine
Authors: Paroha Shweta , Dubey Ravindra Dhar , Verma Juhi , Jain Vikas , Akbar Saleem , Mishra Ashwini Kumar , Neha S.L. , Rani Laxmi , Mahto Aman Kumar , Sahoo Parvat Kumar , Dewangan Rikeshwer Prasad 
Published: February 2025

Abstract:
Gemcitabine (Gem) is a well-known antineoplastic drug used for several solid tumors.
The clinical application of gem is hampered owing to non-selectivity, short half-life, and drug resistance,
which necessitate the development of a suitable novel formulation that can selectively target
cancer sites. In the present work, Gem-loaded bovine serum albumin nanoparticles (Gem-BSANPs)
have been prepared and coated with hyaluronic acid (HA-Gem-BSANPs). Particle size,
zeta potential, TEM, and DSC analysis characterized the developed NPs. The mean particle size,
PDI, and zeta potentials were observed to be 120.9 ± 5.87 vs 144.7 ± 5.67 and 28.66 ± 1.10 vs
-45.72 ± 3.24, for Gem-BSANPs and HA-Gem-BSANPs, respectively. Interestingly, HA-coated
Gem-BSANPs were found higher cytotoxic against A549 cell lines with better killing kinetics and
mitochondrial membrane loss due to overexpression of CD44. The present work demonstrated
that HA-Gem-BSANPs could be a potential strategy to improve the therapeutic efficacy of gem
by selectively targeting to the tumor site.
scZIGVAE: A Variational Graph Attention Autoencoder Based on the
Zero-Inflated Negative Binomial Distribution for Clustering Single-cell
RNA-Seq Data
Authors: Wang Yutian , Gao Ke , Li zhaomei , Liu chuanxin , Ji Cunmei , Qiao Lijuan , Zheng Chunhou 
Published: February 2025

Background:
Single-cell RNA sequencing (scRNA-seq) technology has opened new horizons
in studying cellular diversity, helping researchers distinguish the gene expression patterns of
each cell, identify rare cell types, and explore the dynamics of gene expression in specific cells under
different environments. Clustering plays a central role in revealing unknown cell types and downstream
analysis of scRNA-seq. However, the high dimensionality, high noise, and common data
missing issues in scRNA-seq data significantly limit the performance of clustering. Traditional embedding
algorithms often ignore the characteristics of the underlying distribution when dealing with
scRNA-seq data.

Aims:
In this study, we aim to achieve clustering analysis of single-cell RNA sequencing (scRNAseq)
data by developing and applying a variational graph attention autoencoder model based on the
zero-inflated negative binomial (ZINB) distribution.

Methods:
Therefore, we propose a scRNA-seq data clustering analysis method, scZIGVAE, which
integrates the zero-inflated negative binomial (ZINB) model and variational graph attention autoencoder.
It enhances the learning of complex topological structures between cells while modeling missing
events. By jointly optimizing the ZINB loss and cell graph reconstruction loss to estimate missing
data, scZIGVAE generates cell representations that are more suitable for clustering. Furthermore,
through the method of self-optimizing embedded clustering, the clustering centers are iteratively updated
to fine-tune the clustering effect of the model further.

Results:
Extensive testing on twelve datasets from different single-cell RNA sequencing platforms
has demonstrated that the scZIGVAE method outperforms current sota clustering techniques.

Conclusion:
In summary, our research findings demonstrate that by incorporating the Zero-Inflated
Negative Binomial (ZINB) distribution strategy into the Variational Graph Autoencoder (VGAE) architecture,
we are able to achieve better estimation of missing values during decoding. Furthermore,
the utilization of multiple loss constraints on the generated latent representations renders them more
conducive to downstream analyses.
Integrative Analysis of Metabolomic and Transcriptomic Data Reveals Metabolic Signatures and Major Metabolic Pathways in Primary Aldosteronism
Authors: Lai Xiaomei , Yang Tingting , Wei Chaoping , Zhu Shuangbei , Li Jianling 
Published: February 2025

Objective:
Primary aldosteronism (PA) is the most common secondary hypertension. In
this study, we performed the pathway enrichment analysis based on metabolomics and transcriptomic
data to find the metabolic perturbations in PA, which could provide new targets for PA and
further understand the biology of PA.

Methods:
24 PA patients and 24 healthy adults served as the control group in this study. Six participants
were chosen from each group to have their peripheral blood and serum samples analyzed
for omics investigations. Another eighteen participants' peripheral blood samples were selected
for further validation of the RNA-sequencing results.

Results:
Transcriptomic analyses found 518 differentially expressed genes (DEGs), and 339 remarkably
differential metabolites (DMs) were identified by untargeted metabolomics. The pathway
enrichment analysis was performed by combining with the omics analysis data. We also focused
on analyzing metabolic pathways that repeatedly occur and constructed possible genemetabolic
networks. A total of 5 genes and 11 metabolites showed significant changes in altered 3
lipid metabolic pathways. Furthermore, the expressions of these genes were verified by qRT-PCR.

Conclusion:
The combination of metabolomic and transcriptomic data can give a comprehensive
picture of unique illness markers and preliminary knowledge of the molecular abnormalities underpinning
PA. These findings may point to viable targets for creating treatments.
Electrospun Polyvinyl Alcohol Nanofibers Loaded with Ferula assa-foetida Gum Extract: Fabrication, Characterization, and Antibacterial Activity
Authors: Salimiyan Fatemeh , Asadollahi Mohammad Ali , Behbahani Mandana , Kajani Abolghasem Abbasi 
Published: February 2025

Background:
Therapeutic effects of plant metabolites have been used for the treatment of
burns, wounds and infections over the centuries. Electrospun nanofibers containing plant metabolites
have also been considered recently for the development of new and efficient wound dressings. Ferula
assa-foetida has received much attention in traditional medicine due to its numerous healing properties.

Objective:
In the present study, polyvinyl alcohol (PVA) nanofibers containing aqueous extracts of
F. assa-foetida gum (FAE) were prepared and characterized. The antibacterial activity of nanofibers
was investigated.

Methods:
Electrospinning was utilized for the fabrication of PVA/FAE nanofibers. The morphology,
physical and chemical properties of the synthesized nanofibers were investigated by scanning electron
microscope (SEM), Fourier transform infrared (FTIR) spectroscopy, and contact angle test.

Results:
The uniform nanofibers with the average diameter of 256 nm were obtained by using 8
wt.% PVA, 1:4 (w: w %) ratio of PVA/FAE, needle to collector distance of 13 cm, 20 kV voltage,
collector rotation speed of 3 m/min, and flow rate of 0.5 mL/h. The use of FAE led to the increased
diameter of nanofibers and their contact angle compared to PVA nanofibers. Interestingly, the
PVA/FAE nanofibers displayed considerable antibacterial activity against Escherichia coli and
Staphylococcus aureus.

Conclusion:
The overall results indicated that PVA/FAE nanofibers can be considered as a potential
candidate for the preparation of wound dressings with antibacterial properties.
The Book “Lists of Conscripts by Maloderbetovsky Regional Military Commissariat in 1941, 1942, 1943” as a Source on the History of Participation of Kalmykia Residents in the Great Patriotic War
Authors:   Kalmyk Scientific Center of the RAS, Ochir-Goryaeva Valentina N. 
Published: February 2025

Introduction. The article is devoted to the analysis of the book “Lists of Conscripts by Maloderbetovsky Regional Military Commissariat in 1941, 1942, 1943” as a source on the history of participation of Kalmykia residents in the Great Patriotic War of 1941–1945. The purpose of this article is a detailed review of this book. Materials and methods. The main source for the study was the book “Lists of Conscripts by Maloderbetovsky Regional Military Commissariat in 1941, 1942, 1943” published in 2023 by T. Ts. Kishteeva. In the process of analysis the methods of comparative and descriptive analysis were used, which allowed us to obtain valuable information about the role of the inhabitants of Kalmykia during the war. Results. The book of conscripts contains information about 3 429 servicemen called up by the Maloderbetovsky Regional Military Commissariat. In the process of the analysis it was found out that in some cases the information is repeated, as well as there are errors and inaccuracies in the information. Nevertheless, the book covers a significant number of war participants and serves as an important source to immortalize the memory of our fellow countrymen who fought for the Motherland in 1941–1945.