bluuebunny/crossref_metadata_2025_split huggingface dataset:
Entropy-calibrated stellar modeling: Testing and improving the use of prescriptions for the entropy of adiabatic convection
Authors: Manchon L. , Deal M. , Goupil M.-J. , Serenelli A. , Lebreton Y. , Klevas J. , Kučinskas A. , Ludwig H.-G. , Montalbán J. , Gizon L. 
Published: May 2024

Context. Modeling the convection process is a long-standing problem in stellar physics. To date, all ad hoc models have relied on a free parameter, α, (among others) that has no real physical justification and is therefore poorly constrained. However, a link exists between this free parameter and the entropy of the stellar adiabat. There are existing prescriptions, derived from 3D stellar atmospheric models, that treat entropy as a function of stellar atmospheric parameters (effective temperature, surface gravity, and chemical composition). This can offer sufficient constraints on α through the development of entropy-calibrated models. However, several questions have arisen as these models are increasingly used with respect to which prescription should be used and whether it ought to be used in its original form, along with the impacts of uncertainties on entropy-calibrated models.
Aims. We aim to study the three existing prescriptions in detail and determine which of them demonstrate the most optimal performance and how it should be applied.
Methods. We implemented the entropy-calibration method into the stellar evolution code (Cesam2k20) and performed comparisons with the Sun and the α Cen system. In addition, we used data from the CIFIST grid of 3D atmosphere models to evaluate the accuracy of the prescriptions.
Results. Of the three entropy prescriptions currently available, we determined the one that has the best functional form for reproducing the entropies of the 3D models. However, the coefficients involved in this formulation must not be taken from the original paper because they were calibrated against a flawed set of entropies. We also demonstrate that the entropy obtained from this prescription should be corrected for the evolving chemical composition and for an entropy offset different between various EoS tables. This must be done following a precise procedure to ensure that the classical parameters obtained from the models are not strongly biased. Finally, we provide a data table with entropy of the adiabat of the CIFIST grid, along with the fits for these entropies.
Conclusions. Thanks to a precise examination of entropy-calibrated modeling, we are able to offer our recommendations with respect to which adiabatic entropy prescription to use, how to correct it, and how to implement the method into a stellar evolution code.
Ionised AGN outflows in the Goldfish galaxy: The illuminating and interacting red quasar eFEDSJ091157.4+014327 atz∼ 0.6
Authors: Musiimenta B. , Speranza G. , Urrutia T. , Brusa M. , Ramos Almeida C. , Perna M. , López I. E. , Alexander D. , Laloux B. , Shankar F. , Lapi A. , Salvato M. , Toba Y. , Andonie C. , Rodríguez I. M. 
Published: May 2024

Context.Evolutionary models suggest that the initial growth phases of active galactic nuclei (AGN) and their central supermassive black holes (SMBHs) are dust-enshrouded and characterised by jet or wind outflows that should gradually clear the interstellar medium (ISM) in the host by heating and/or expelling the surrounding gas. eFEDSJ091157.4+014327 (z ∼ 0.6) was selected from X-ray samples of eROSITA (extended ROentgen Survey with an Imaging Telescope Array) for its characteristics: red colours, X-ray obscuration (NH= 2.7 × 1022cm−2) and luminous (LX = 6.5 × 1044erg s−1), similar to those expected in quasars with outflows. It hosts an ionised outflow as revealed by a broad [O III]λ5007 Å emission line in the SDSS integrated spectrum. For a proper characterisation of the outflow properties and their effects, we need spatially resolved information.Aims.We aim to explore the environment around the red quasar, morphology of the [O III] gas and characterise the kinematics, mass outflow rates and energetics within the system.Methods.We used spatially resolved spectroscopic data from Multi Unit Spectroscopic Explorer (MUSE) with an average seeing of 0.6″ to construct flux, velocity and velocity dispersion maps. Thanks to the spatially resolved [O III]λ5007 Å emission detected, we provide insights into the morphology and kinematics of the ionised gas and better estimates of the outflow properties.Results.We find that the quasar is embedded in an interacting and merging system with three other galaxies ∼50 kpc from its nucleus. Spatially resolved kinematics reveal that the quasar has extended ionised outflows of up to 9.2−0.4+1.2kpc with positive and negative velocities up to 1000 km s−1and −1200 km s−1, respectively. The velocity dispersion (W80) ranges from 600–1800 km s−1. We associate the presence of high-velocity components with the outflow. The total mass outflow rate is estimated to be ∼10M⊙yr−1, a factor of ∼3–7 higher than the previous findings for the same target and kinetic power of 2 × 1042erg s−1. Considering different AGN bolometric luminosities, the kinetic coupling efficiencies range from 0.01%–0.03% and the momentum boosts are ∼0.2.Conclusions.The kinetic coupling efficiency values are low, which indicates that the ionised outflow is not energetically relevant. These values don’t align with the theoretical predictions of both radiation-pressure-driven outflows and energy-conserving mechanisms. However, note that our results are based only on the ionised phase while theoretical predictions are multi-phase. Moreover, the mass loading factor of ∼5 is an indication that these outflows are more likely AGN-driven than star formation-driven.
A pilot project for energy retrofit of educational buildings - The engineering campus of the University of L’Aquila
Authors: de Rubeis Tullio , Smarra Francesco , Franchi Fabio , Di Battista Davide , D’Innocenzo Alessandro , Ambrosini Dario , De Berardinis Pierluigi 
Published: May 2024

The engineering campus of the University of L’Aquila represents a complex use case in the context of energy efficiency, mainly due to its size, the high thermal power, the hybrid hydronic and ventilation system, the absence of a room’s thermal control, and the progressive obsolescence of the heating plant.
An in-depth recognition and study of the campus’ HVAC system made it possible to assess the main energy inefficiencies and define interventions to improve its performance.
The energy retrofit, carried out by the University’s “Energy Commission Workgroup”, highlighted the main criticalities and potentials of the HVAC system providing viable paths for energy optimization. Among them, one of the hypothesized interventions concerned the thermal regulation of the heating plant, which is, to date, substantially absent.
This work presents the results of a Pilot Project to quantitatively evaluate the effectiveness of the closed-loop control on a thermal system. Two classrooms in the Engineering Campus, similar in geometry, orientation, and occupancy, were selected. One of them has been equipped with a control system. The results of the monitoring campaign showed that the proposed system achieved more than 30% energy savings over a three-month trial period.
Systemischer Lupus Erythematodes 2023
Authors: Mucke Johanna , Aringer Martin 
Published: May 2024

ZusammenfassungMit zwei neuen Zulassungen in den letzten Jahren, einem Update der EULAR
Empfehlungen zum Management des systemischer Lupus erythematodes (SLE) 2023 und
neuen, vielversprechenden Therapieoptionen konnten in der SLE-Therapie
bedeutende Fortschritte erzielt werden. Nach wie vor steht der individuelle
Patient im Fokus, und Therapieansätze richten sich nach Manifestationen und
Patientencharakteristika. Durch das erweitere Armamentarium stehen nun jedoch
mehr Optionen zu Verfügung.
How to Approach the Difficult Perineum in Crohn's Disease
Authors: Rinebold Emily , Huang Alex L. , Hahn Sue J. 
Published: May 2024

AbstractCrohn's disease (CD) is a chronic, inflammatory bowel disease with a wide range of presentations, including perianal disease. Presentation is variable, ranging from skin tags to complex fistulas, strictures, and nonhealing wounds. Symptoms of perianal CD can be devastating and may impact quality of life. Optimal management requires coordinated medical and surgical therapy. When possible, conservative treatment of perianal disease should be attempted. However, surgical treatment is often required, and some patients may ultimately require total proctocolectomy with permanent diversion due to the severity of disease. Even with close attention and treatment, disease can be recurrent, and complications of treatment are sometimes worse than the initial presentation. Novel treatments, including use of mesenchymal stem cells and autologous fat grafting, hold some promise, but are not yet widely available. Thorough knowledge of treatment options, careful patient selection, coordination between medical and surgical providers, and setting realistic expectations are important in the successful treatment of difficult perineal CD.
Neuromonitoring in a Case with Midbrain Cavernoma Operated in Sitting Position: Unveiling the Complexities
Authors: Rebello Joslita , Thakore Bhoomika 
Published: May 2024

AbstractThe sitting position is often utilized for mid-brain cavernoma excision due to its several surgical advantages. Intraoperative neuromonitoring aids dynamic functional assessment of neural structures in real-time. In this case report, we discuss the anesthetic management of a patient scheduled for midbrain cavernoma excision in a sitting position. Evoked potential monitoring was performed as the tumor was in proximity to cortico-spinal tracts. We used a combination of inhalational and intravenous anesthetics for the maintenance of anesthesia. Intraoperatively significant events included two episodes of venous air embolism, and loss of motor evoked potentials during the resection of the tumor. These complications were promptly recognized and managed. In the early postoperative period, the patient had motor power 3/5 in flexors of the right upper limb, which improved to normal by Day 5. Thus, good communication among anesthesiologists, neurologists, and surgeons helped identify altered evoked potential signals early, aiding the modification of dissection accordingly.
Management, Utilization, and Outcomes of Preterm Labor in an Integrated Health Care System
Authors: Getahun Darios , Sacks David A. , Shi Jiaxiao , Xie Fagen , Khadka Nehaa , Chiu Vicki Y. , Mensah Nana A. , Avila Chantal C. , Yeh Meiyu , Kawatkar Aniket A. , Ruma Michael S. , Joyce Derek , Fassett Michael J. 
Published: May 2024

Objective Fetal fibronectin (fFN) testing and transvaginal ultrasound (TVUS) are diagnostic tools used to predict impending spontaneous preterm birth (sPTB) among women presenting with preterm labor (PTL). We evaluated the association between fFN testing or TVUS cervical length (CL) measurement in predicting sPTB, respiratory distress syndrome (RDS), neonatal intensive care unit (NICU) admission, and sPTB-related costs.
Study Design We conducted a retrospective cohort study using data from the Kaiser Permanente Southern California electronic health system (January 1, 2009–December 31, 2020) using diagnostic and procedure codes, along with a natural language processing algorithm to identify pregnancies with PTL evaluations. PTL evaluation was defined as having fFN and/or TVUS assessment. Outcomes were ascertained using diagnostic, procedural, and diagnosis-related group codes. Multivariable logistic regression assessed the association between fFN and/or TVUS results and perinatal outcomes.
Results Compared with those without PTL evaluations, those with positive fFN tests had higher adjusted odds ratio (adj.OR) for sPTB (2.95, 95% confidence interval [CI]: 2.64, 3.29), RDS (2.34, 95% CI: 2.03, 2.69), and NICU admission (2.24, 95% CI: 2.01, 2.50). In contrast, those who tested negative had lower odds for sPTB (adj.OR: 0.75, 95% CI: 0.70, 0.79), RDS (adj.OR: 0.67, 95% CI: 0.61, 0.73), and NICU admission (adj.OR: 0.74, 95% CI: 0.70, 0.79). Among those with positive fFN results, the odds of sPTB was inversely associated with CL. Health care costs for mothers and neonates were lowest for those with fFN testing only.
Conclusion This study demonstrates that positive fFN results were associated with an increased odds of sPTB, RDS, and NICU admission and the association with sPTB was inversely proportional to CL. Additionally, negative fFN results were associated with decreased odds of sPTB, RDS, and NICU admissions. fFN testing may predict these and other sPTB-related adverse outcomes hence its utility should be explored further. Moreover, fFN testing has some cost savings over TVUS.
Key Points
Is the Risk of Intrahepatic Cholestasis Increased with Supplemental Progesterone?
Authors: Rohn Matthew C.H. , Vignali Lindsey , Reeder Isabel , Khosravian Kiana , Petersen Scott 
Published: May 2024

Objective This study aimed to evaluate the relationship between supplemental progesterone use during pregnancy and the development of intrahepatic cholestasis of pregnancy (ICP).
Study Design A retrospective, matched case–control study was conducted among a population of women who delivered at George Washington University Hospital (GW) between 2012 and 2022. Women diagnosed with ICP (cases) were identified using International Statistical Classification of Diseases (ICD) codes, and data were collected via chart abstraction. Descriptive data included patient demographics, pregnancy characteristics, and medical history. Laboratory values related to ICP were collected. Cases were matched on a 1:3 ratio by maternal age, body mass index, and gravidarum to women who delivered at GW during the same month and did not carry a diagnosis of ICP (controls). A univariate logistic regression model was created to assess the use of supplemental progesterone between groups, adjusting for the use of assisted reproductive technology in the current pregnancy, and a history of liver disease.
Results One hundred and twenty women who delivered during the study period were confirmed to have a diagnosis of ICP. Cases were matched with 360 controls and measures compared between the two groups. Cases were significantly more likely to have a history of liver disease (5.9 vs. 1.7%, p = 0.0021), multiple gestation (10.0 vs. 3.3%, p < 0.0001), a history of ICP in a previous pregnancy (10.0 vs. 0%, p < 0.0001), and to have delivered at an earlier gestational age (mean 37.1 vs. 38.6 weeks, p < 0.0001) as compared with controls. No differences were seen in the odds of supplemental progesterone use in both unadjusted and adjusted models (OR = 1.14, 95% CI: 0.30–4.34; adjusted Odds Ratio [aOR] = 0.98 [0.24–3.94]).
Conclusion Contrary to recent evidence, no association was seen with the use of supplemental progesterone. It is possible that the associated risk with supplemental progesterone is dependent on medication formulation or route of administration.
Key Points
Therapeutic Hypothermia for Neonatal Hypoxic–Ischemic Encephalopathy: Reducing Variability in Practice through a Collaborative Telemedicine Initiative
Authors: Leandro Danieli M.K. , Variane Gabriel F.T. , Dahlen Alex , Pietrobom Rafaela F.R. , de Castro Jessica A.R.R. , Rodrigues Daniela P. , Magalhães Mauricio , Mimica Marcelo J. , Van Meurs Krisa P. , Chock Valerie Y. 
Published: May 2024

Objective This study aimed to assess the viability of implementing a tele-educational training program in neurocritical care for newborns diagnosed with hypoxic–ischemic encephalopathy (HIE) and treated with therapeutic hypothermia (TH), with the goal of reducing practice variation.
Study Design Prospective study including newborns with HIE treated with TH from 12 neonatal intensive care units in Brazil conducted from February 2021 to February 2022. An educational intervention consisting of 12 biweekly, 1-hour, live videoconferences was implemented during a 6-month period in all centers. Half of the centers had the assistance of a remote neuromonitoring team. The primary outcome was the rate of deviations from TH protocol, and it was evaluated during a 3-month period before and after the intervention. Logistic regression via generalized estimating equations was performed to compare the primary and secondary outcomes. Protocol deviations were defined as practices not in compliance with the TH protocol provided. A subanalysis evaluated the differences in protocol deviations and clinical variables between centers with and without neuromonitoring.
Results Sixty-six (39.5%) newborns with HIE were treated with TH during the preintervention period, 69 (41.3%) during the intervention period and 32 (19.1%) after intervention. There was not a significant reduction in protocol deviations between the pre- and postintervention periods (37.8 vs. 25%, p = 0.23); however, a decrease in the rates of missing Sarnat examinations within 6 hours after birth was seen between the preintervention (n = 5, 7.6%) and postintervention (n = 2, 6.3%) periods (adjusted odds ratio [aOR]: 0.36 [0.25–0.52], p < 0.001). Centers with remote neuromonitoring support had significantly lower rates of seizures (27.6 vs. 57.5%; aOR: 0.26 [0.12–0.55], p < 0.001) and significant less seizure medication (27.6 vs. 68.7%; aOR: 0.17 [0.07–0.4], p < 0.001).
Conclusion This study shows that implementing a tele-educational program in neonatal neurocritical care is feasible and may decrease variability in the delivery of care to patients with HIE treated with TH.
Key Points
The blocking and transmission effects of lower level system in patent transaction - evidence from Chinese colleges and universities
Authors: Junrong Zhang 
Published: May 2024

AbstractConflicts and contradictions within the legal system may affect the effectiveness of law enforcement, but scholars have not conducted sufficient empirical research on the mechanism. Based on three periods of mixed cross-sectional data in 2015 and 2019 when the reform of patent transaction system in colleges and universities, which represents a quasi-natural experiment, has been carried out, this study adopted a difference-in-difference (DID) model to empirically analyze the efficiency of patent transactions. It was found that if the lower level system was not removed or revised in time when the higher level law had been revised, it would have a blocking effect on the implementation of the higher level law and thus make patent transaction less efficient. Furthermore, when the lower level system was revised accordingly, it would have a transmission effect on the implementation of the higher level law, which could promote its implementation. This basic conclusion remains valid after a series of robustness tests and can provide useful lessons for the systemic revision and organizing of laws, as well as the reform of the economic and social systems.
Development and application of a three-dimensional pseudo-Voigt function for muon spin relaxation analysis of weakly magnetic materials
Authors: Umar M. D. , Hariyanto H. L. , Absor M. A. U. 
Published: May 2024

We present a three-dimensional pseudo-Voigt function to analyze muon spin relaxation (μSR) in weakly magnetic materials. Our approach approximates the Voigt function by superimposing Gaussian and Lorentzian functions using a one-dimensional method proposed by Di Rocco and Cruzado [Acta Phys. Pol., A 122, 666 (2012)]. We derive the peak of the Voigt function analytically and express the Half Width at Half Maximum (HWHM) of the Voigt function as a function of the HWHMs of the Gaussian and Lorentzian functions. We compare the pseudo-Voigt function to the exact Voigt function and find a maximum normalized discrepancy of ∼20% at the tail of the distribution function, depending on the ratio of Lorentzian to Gaussian HWHMs and internal magnetic field. We apply the derived three-dimensional pseudo-Voigt function to calculate μSR functions for zero- and longitudinal-field experiments and use them to fit μSR time spectra of La2−xSrxCuO4 with 2.4% Sr, employing a strong collision model with the static-based pseudo-Voigt muon spin relaxation function as the initial condition. Our results show that the Gaussian- and Lorentzian-fitted parameters and fluctuation rate are in good agreement with results from the exact Voigt function for a temperature range of 30–200 K, with the deviation of Gaussian and Lorentzian width parameters reaching ∼0.15 G below 30 K.
A broadband pulse amplifier for Joule heating experiments in diamond anvil cells
Authors: Geballe Zachary M. , Lai Joseph , Walter Michael J. 
Published: May 2024

Decades of measurements of the thermophysical properties of hot metals show that pulsed Joule heating is an effective method to heat solid and liquid metals that are chemically reactive or difficult to contain. To extend such measurements to hundreds of GPa pressure, pulsed heating methods have recently been integrated with diamond anvil cells. The recent design used a low-side switch and active electrical sensing equipment that was prone to damage and measurement error. Here, we report the design and characterization of new electronics that use a high-side switch and robust, passive electrical sensing equipment. The new pulse amplifier can heat ∼5 to 50 μm diameter metal wires to thousands of kelvin at tens to hundreds of GPa using diamond anvil cells. Pulse durations and peak currents can each be varied over three orders of magnitude, from 5 µs to 10 ms and from 0.2 to 200 A. The pulse amplifier is integrated with a current probe. Two voltage probes attached to the body of a diamond anvil cell are used to measure voltage in a four-point probe geometry. The accuracy of four-point probe resistance measurements for a dummy sample with 0.1 Ω resistance is typically better than 5% at all times from 2 µs to 10 ms after the beginning of the pulse.
How does crosstalk influence the jitter of a clock signal?
Authors: Liao Shuang , Wang Houjun , Tong Yuchen , Chen Cheng , Tan Feng , Guo Lianping 
Published: May 2024

The stability and accuracy of the clock signal are crucial for the proper operation of various electronic devices and systems, as they directly impact system performance. In high-speed electronic systems, the clock signal is susceptible to interference by crosstalk. Therefore, evaluating the performance of the clock signal under crosstalk disturbance is important. Jitter, commonly used as an indicator to assess the degree of this interference, plays a significant role in this evaluation. In this paper, a method is proposed for assessing crosstalk-induced jitter (CIJ) based on scattering parameters. To verify the effectiveness of the method, CIJ was measured for clock signals with frequencies of 25, 100, and 156.25 MHz. In addition, the experimental results are well in agreement with the theoretical model. Thus, the potential application of this method is to assess the performance of circuits or electronic systems.