bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meromorphic extensions from small families of circles and holomorphic extensions from spheres
Authors: Globevnik Josip 
Published: May 2012

Let

B

\mathbb {B}

be the open unit ball in

C

2

\mathbb {C}^2

and let

a
,
b
,
c

a, b, c

be three points in

C

2

\mathbb {C}^2

which do not lie in a complex line, such that the complex line through

a
,
b

a, b

meets

B

\mathbb {B}

and such that if one of the points

a
,
b

a, b

is in

B

\mathbb {B}

and the other in

C

2

∖

B

¯

\mathbb {C}^2\setminus \overline {\mathbb {B}}

then

⟨
a

|

b
⟩
≠
1

\langle a|b\rangle \not = 1

and such that at least one of the numbers

⟨
a

|

c
⟩
,

⟨
b

|

c
⟩

\langle a|c\rangle ,\ \langle b|c\rangle

is different from

1
1

. We prove that if a continuous function

f
f

on

b

B

b\mathbb {B}

extends holomorphically into

B

\mathbb {B}

along each complex line which meets

{
a
,
b
,
c
}

\{ a, b, c\}

, then

f
f

extends holomorphically through

B

\mathbb {B}

. This generalizes the recent result of L. Baracco who proved such a result in the case when the points

a
,
b
,
c

a, b, c

are contained in

B

\mathbb {B}

. The proof is quite different from the one of Baracco and uses the following one-variable result, which we also prove in the paper: Let

Δ
\Delta

be the open unit disc in

C

\mathbb {C}

. Given

α
∈
Δ

\alpha \in \Delta

let

C

α

\mathcal {C}_\alpha

be the family of all circles in

Δ
\Delta

obtained as the images of circles centered at the origin under an automorphism of

Δ
\Delta

that maps

0
0

to

α
\alpha

. Given

α
,
β
∈
Δ
,

α
≠
β

\alpha , \beta \in \Delta ,\ \alpha \not = \beta

, and

n
∈

N

n\in \mathbb {N}

, a continuous function

f
f

on

Δ
¯

\overline {\Delta }

extends meromorphically from every circle

Γ
∈

C

α

∪

C

β

\Gamma \in \mathcal {C}_\alpha \cup \mathcal {C}_\beta

through the disc bounded by

Γ
\Gamma

with the only pole at the center of

Γ
\Gamma

of degree not exceeding

n
n

if and only if

f
f

is of the form

f
(
z
)
=

a
0

(
z
)
+

a
1

(
z
)

z
¯

+
⋯
+

a
n

(
z
)

z
¯

n

(
z
∈
Δ
)

f(z) = a_0(z)+a_1(z)\overline z +\cdots +a_n(z)\overline z^n (z\in \Delta )

where the functions

a
j

,
0
≤
j
≤
n

a_j, 0\leq j\leq n

, are holomorphic on

Δ
\Delta

.
An observational study of the Baska® mask: a novel supraglottic airway*
Authors: Alexiev V. , Salim A. , Kevin L. G. , Laffey J. G. 
Published: May 2012

SummaryThe Baska mask is a novel supraglottic airway device. We conducted an initial observational study to assess this device in 30 low‐risk female patients. All Baska masks were inserted by a single investigator. The overall success rate for device insertion was 96.7% (95% CI 82.8–99.9%), while the success rate for the first insertion attempt was 76.7% (95% CI 57.7–90.1%). The device was easy to insert, with a mean (SD) difficulty score of 0.9 (1.6) on a 10‐cm scale. The mean (SD) airway leak pressure was 35.7 (13.3) cmH2O. The incidence of throat pain, dysphonia and dysphagia was low. We conclude that the Baska mask demonstrates a level of utility as an alternative supraglottic airway that is worthy of further clinical study.
Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates
Authors: Degré D , Lemmers A , Gustot T , Ouziel R , Trépo E , Demetter P , Verset L , Quertinmont E , Vercruysse V , Le Moine O , Devière J , Moreno C 
Published: May 2012

Summary
Serum levels and liver expression of CCL2 are increased in patients with alcoholic hepatitis (AH). In an experimental model of alcoholic liver disease (ALD), CCL2 was implicated in proinflammatory cytokines activation and hepatic lipid metabolism, but its role in human disease is currently unknown. In a large cohort of ALD patients, we analysed plasma levels and liver expression of CCL2 and their association with liver disease severity and histological lesions. We also studied the relationship between −2518 A &gt; G CCL2 and CCR2 190 A/G polymorphisms and severity of ALD. We show that CCL2 plasma levels are increased in ALD patients compared with healthy subjects. AH patients had significantly higher plasma levels and hepatic expression of CCL2 than patients without AH. Plasma levels and hepatic expression of CCL2 were associated with disease severity. CCL2 liver expression was correlated with neutrophil infiltrate and interleukin (IL)-8 expression, but not with steatosis. Moreover, there were more G-allele carriers of −2518 A &gt; G CCL2 polymorphism in severe AH patients than in other ALD patients. Our results demonstrate that CCL2 is increased in ALD, particularly in severe forms, and suggest a role for CCL2 in the pathogenesis of ALD via neutrophil recruitment.
The effects of treatment with drospirenone/ethinyl oestradiol alone or in combination with metformin on elastic properties of aorta in women with polycystic ovary syndrome
Authors: Kaya Mehmet G. , Calapkorur Bekir , Karaca Zuleyha , Yildirim Sumeyra , Celik Ahmet , Akpek Mahmut , Unluhizarci Kursad , Kelestimur Fahrettin 
Published: May 2012

SummaryBackgroundPolycystic ovary syndrome (PCOS) is a heterogeneous clinical condition. Oral contraceptive pills (OCPs) have conventionally been the mainstay of treatment for the amelioration of hyperandrogenism and regulation of menstrual cycles in women with PCOS. Metformin has beneficial effects on insulin resistance and endothelial functions. To our knowledge, the effect of metformin/OCP combination treatment on aortic stiffness has not been studied so far.ObjectiveThe aim of this study was to investigate the effects of treatment with drospirenone/ethinyl oestradiol (E/E) alone or in combination with metformin on the elastic properties of the aorta in women with PCOS.MethodsThirty‐seven women with PCOS were enrolled in the study. The first treatment arm, which was treated with OCP alone, was described as the OCP group (19 patients, mean age: 23·2 ± 5·4); the other treatment arm, which was treated with OCP and metformin, was described as the combination group (18 patients, mean age: 23·0 ± 4·5). The elastic parameters of the aorta namely ‘aortic strain’, ‘aortic distensibility’, ‘aortic diameter alteration’ and ‘aortic stiffness index’ were calculated by the appropriate formulae. The hormonal profile, HOMA‐IR score, basal insulin and glucose levels were studied in both groups. Before and after 6 months of treatment, echocardiographic measurements and laboratory tests were also obtained.ResultsAfter 6 months of treatment, significant weight loss and decrease in body mass index (BMI) were observed in the combination group (75·3 ± 13·3 kg to 72·3 ± 13·5 kg and 31·7 ± 7·3 kg/m² vs 30·4 ± 7·3 kg/m², P = 0·001 and P = 0·001, respectively). Conversely in the OCP group, BMI and weight were not significantly different after 6 months of treatment (68·8 ± 18·3 kg to 71·6 ± 21·2 kg and 26·4 ± 6·2 kg/m² to 27·4 ± 6·9 kg/m², P = 0·159 and P = 0·149, respectively). In addition, there were no significant differences in aortic strain, distensibility (7·7 ± 4·2 to 7·8 ± 3·6 and 7·2 ± 4·1 to 7·7 ± 3·6, P = 0·926 and P = 0·593, respectively) and stiffness index in the OCP group (8·8 ± 7·4 to 8·2 ± 6·7, P = 0·772). However, in the combination group, the adjusted values of the aortic stiffness index decreased significantly at the 6 months' follow‐up (10·0 ± 1·5 to 6·7 ± 0·3, P = 0·021) and aortic distensibility and strain increased but not significantly (7·0 ± 4·3 to 9·3 ± 3·3 and 6·8 ± 3·9 to 9·4 ± 3·5, P = 0·163 and P = 0·071, respectively) at the 6 months' follow‐up.ConclusionWe demonstrated an improvement in the elastic parameters of the aorta by adding metformin to OCP treatment. We suggest that metformin plus OCP treatment may decrease cardiovascular disease risk in women with PCOS.
A gradient‐ratio method for the semi‐automatic interpretation of gravity map data sets
Authors: Cooper G.R.J. 
Published: May 2012

ABSTRACTThe application of semi‐automatic interpretation techniques to potential field data can be of significant assistance to a geophysicist. This paper generalizes the magnetic vertical contact model tilt‐depth method to gravity data using a vertical cylinder and buried sphere models. The method computes the ratio of the vertical to the total horizontal derivative of data and then identifies circular contours within it. Given the radius of the contour and the contour value itself, the depth to the source can be determined. The method is applied both to synthetic and gravity data from South Africa. The Matlab source code can be obtained from the author upon request.
Rock physics interpretation of heterogeneous and anisotropic turbidite reservoirs
Authors: Golikov Pavel , Avseth Per , Stovas Alexey , Bachrach Ran 
Published: May 2012

ABSTRACTIn this paper, we create rock physics templates for heterogeneous and anisotropic thin‐bedded sand‐shale intervals as a function of group angle, net‐to‐gross, saturation and porosity as variable parameters. These templates are basically cross‐plots of acoustic impedance versus P‐ to S‐velocity ratio. We apply these templates to interpret well log data from a vertical and a deviated well, respectively, in a North Sea turbidite system. We are able to infer the shale anisotropic elastic moduli and Thomsen parameters by comparing the measured velocities in a deviated well with the velocities in an adjacent vertical well. Our modeling captures the observed trends in the data as we go from a vertical well to a deviated well through a heterogeneous reservoir saturated with light oil and water. We can clearly see how the reservoir properties changes due to the presence of anisotropy. We also perform an AVO sensitivity study as a function of heterogeneity and hydrocarbon saturation.
Multiple osteolytic lesions of intraosseous adenoid cystic carcinoma in the mandible mimicking apical periodontitis
Authors: Grimm M. , Henopp T. , Hoefert S. , Schaefer F. , Kluba S. , Krimmel M. , Reinert S. 
Published: May 2012

AbstractGrimm M, Henopp T, Hoefert S, Schaefer F, Kluba S, Krimmel M, Reinert S. Multiple osteolytic lesions of intraosseous adenoid cystic carcinoma in the mandible mimicking apical periodontitis. International Endodontic Journal.AimAdenoid cystic carcinoma (ACC) is a relatively rare epithelial tumour of the salivary glands in the maxillofacial region. About 40–60% of the patients develop distant metastases, which have been documented most commonly in the lung but also in brain, bone, liver, thyroid, spleen and pancreatic gland.SummaryA 55‐year‐old women with intraosseous ACC in the mandible mimicking apical periodontitis following curative resection and radiotherapy is presented. Three years later, multiple lung metastases were observed followed by chemotherapy. Five years after curative resection, the patient presented simultaneously with new expansive soft tissue in the pancreas and mammary gland as well as in the kidney found to be metastatic ACC. No case has been reported to date on the manifestation of distant metastases of intraosseous ACC in the breast and the kidney as described by these observations. Metastatic mammary gland ACC stained positive for epithelial growth factor receptor (EGFR) but was negative for HER‐2/neu and Cyclooxygenase‐2 (COX‐2) expression.
Combination of astaxanthin and fish oil supplementation alters antioxidant enzyme profile of dental pulp tissue
Authors: Leite M. F. , Lima A. M. , Otton R. 
Published: May 2012

AbstractAimTo evaluate the effect of administration of astaxanthin (ASTA) and fish oil (FO) on enzymatic antioxidant parameters of dental pulp tissue from healthy rats.MethodologyThirty‐two healthy Wistar rats were divided into four groups: untreated control, ASTA‐treated (1 mg kg−1 body weight), FO‐treated (10 mg eicosapentaenoic acid per kg BW and 7 mg docosahexaenoic acid per kg BW) and FO plus ASTA‐treated. A prophylactic dose was administered in each group daily by gavage, 5 days a week, for 45 days. After treatment, the rats were killed and all incisor dental pulps were removed. Superoxide dismutase (SOD), catalase, glutathione (GSH) peroxidase and reductase activities were determined. Data were compared by anova and the Tukey's post‐test (
P
< 0.05).ResultsTreatment with FO, ASTA and FO plus ASTA caused a reduction in SOD and GSH reductase activities in dental pulp tissue compared to untreated control rats (
P
< 0.05). ASTA partially stimulated catalase activity.ConclusionsThe preventive administration of ASTA and FO changed the enzymatic antioxidant system of dental pulp tissue, possibly by controlling oxidative stress.
Effect of cleaning method, luting agent and preparation procedure on the retention of fibre posts
Authors: Bitter K. , Eirich W. , Neumann K. , Weiger R. , Krastl G. 
Published: May 2012

AbstractBitter K, Eirich W, Neumann K, Weiger R, Krastl G. Effect of cleaning method, luting agent and preparation procedure on the retention of fibre posts. International Endodontic Journal.AimTo investigate the effects of various cleaning methods, luting agents and preparation procedures on fibre post retention.MethodologyIn total, 156 human canines were allocated to twelve groups. Teeth were decoronated, instrumented and root filled using warm vertical gutta‐percha compaction. Post space preparation was performed in 78 roots using the dedicated preparation drills of the DT Light Post SL system [group post drill (PD)]. Gutta‐percha was removed from the other 78 roots using a round bur (RB) (group RB). Within each of these two groups, 26 root canals were rinsed with 1% NaOCl (control), 26 were cleaned using rotating brushes and pumice powder, and 26 were sandblasted with Al2
O
3 (50 μm) using an intraoral device. Cleanliness of each root canal was investigated using an operating microscope (n = 24) and scanning electron microscope (n = 2). Fibre posts were inserted using self‐adhesive resin cement (SmartCem2) or core build‐up material (CoreX Flow/XP Bond). Pull‐out force was measured using a universal testing machine. Statistical analyses were performed using three‐way anova and Tukey's HSD
post hoc tests.ResultsRoot canal cleanliness was not affected by the cleaning method (P = 0.618, chi‐squared test). Pull‐out force for fibre posts was significantly affected by the cleaning method (P = 0.008), the luting agent (P < 0.0005) and the preparation procedure (P < 0.0005, three‐way anova). RB group demonstrated significantly higher pull‐out forces [399 (88) N] compared with PD group [287 (105) N]. Posts that were inserted using CoreX Flow/XP Bond exhibited significantly higher pull‐out forces [370 (62) N] compared with posts inserted using SmartCem2 [315 (141) N].ConclusionThe different cleaning methods did not lead to significant differences in root canal cleanliness and did not enhance fibre post retention inside the root canal. However, post space preparation using a RB might be beneficial for improving retention, especially when self‐adhesive cements are used. The use of the core build‐up material CoreX Flow/XP Bond instead of the self‐adhesive resin cement, SmartCem 2, resulted in significantly higher pull‐out force.
Polar lakes may act as ecological islands to aquatic protists
Authors: RENGEFORS K. , LOGARES R. , LAYBOURN‐PARRY J. 
Published: May 2012

AbstractA fundamental question in ecology is whether microorganisms follow the same patterns as multicellular organisms when it comes to population structure and levels of genetic diversity. Enormous population sizes, predominately asexual reproduction and presumably high dispersal because of small body size could have profound implications on their genetic diversity and population structure. Here, we have analysed the population genetic structure in a lake‐dwelling microbial eukaryote (dinoflagellate) and tested the hypothesis that there is population genetic differentiation among nearby lake subpopulations. This dinoflagellate occurs in the marine‐derived saline lakes of the Vestfold Hills, Antarctica, which are ice‐covered most of the year. Clonal strains were isolated from four different lakes and were genotyped using amplified fragment length polymorphism (AFLP). Our results show high genetic differentiation among lake populations despite their close geographic proximity (<9 km). Moreover, genotype diversity was high within populations. Gene flow in this system is clearly limited, either because of physical or biological barriers. Our results discard the null hypothesis that there is free gene flow among protist lake populations. Instead, limnetic protist populations may differentiate genetically, and lakes act as ecological islands even on the microbial scale.
Surveillance of contact allergies: methods and results of the Information Network of Departments of Dermatology (IVDK)
Authors: Schnuch A. , Geier J. , Lessmann H. , Arnold R. , Uter W. 
Published: May 2012

AbstractContact allergy (CA) surveillance networks provide information to a multitude of stakeholders, which is indispensable for evidence‐based decision‐making in the field of prevention. Methods and results of the German surveillance system on CA are reviewed and discussed with reference to other systems. The German network structure comprises 56 departments of dermatology and includes all patients who are patch‐tested for suspected CA. Data analysis considers the results of patch testing and further pertinent information for each patient. Following aspects are addressed: (i) the description of the clinical population, (ii) evaluation of patch test reactions, (iii) relationship between patch test results and population characteristics. Trend analyses on chromate (decreasing), epoxy resin (increasing) and nickel (heterogeneous) served as examples for surveillance system analyses, with the identification of sentinel events, as well as proof of success or failure of prevention. In addition, external data sources can be used such as sales data of patch test preparations to estimate frequencies of sensitization on a population level. National prescription data of drugs and statistics of labelling of preservatives on cosmetics can be included, the latter two approaches allowing for risk estimates conferred by specific allergens.
Recombinant IGFBP‐3 inhibits allergic lung inflammation, VEGF production, and vascular leak in a mouse model of asthma
Authors: Kim S. R. , Lee K. S. , Lee K. B. , Lee Y. C. 
Published: May 2012

AbstractBackgroundVascular endothelial growth factor (VEGF) plays a pro‐inflammatory mediator as well as a vascular permeability factor in bronchial asthma. Insulin‐like growth factor (IGF)‐I is also involved in the inflammatory process associated with bronchial asthma and stimulates VEGF expression. The IGF‐binding proteins (IGFBPs), especially IGFBP‐3, display distinctive properties and can interfere with various biological processes.MethodsIn this study, an ovalbumin (OVA)‐induced murine model of allergic airway disease was used to investigate which mechanism is implicated in the preventive and therapeutic actions of IGFBP‐3 administered exogenously on allergen‐induced bronchial inflammation and airway hyper‐responsiveness, in particular focusing on the regulation of VEGF expression.ResultsAdministration of recombinant human IGFBP‐3 to OVA‐inhaled mice substantially attenuated the increases in hypoxia‐inducible factor (HIF)‐α activity, IGF‐I production, and VEGF protein levels in the lung. In addition, the blockade of IGF‐I action decreased the OVA‐induced VEGF expression, airway inflammation, and bronchial hyper‐responsiveness. The administration of recombinant human IGFBP‐3 or CBO‐P11 also reduced significantly increases in inflammatory cells, airway hyper‐responsiveness, levels of IL‐4, IL‐5, IL‐13, and vascular permeability in the lung of OVA‐inhaled mice. Moreover, when recombinant human IGFBP‐3 was administered after the completion of OVA inhalation, these therapeutic effects of IGFBP‐3 were also observed.ConclusionsThese results indicate that IGFBP‐3 administered exogenously may attenuate antigen‐induced airway inflammation and hyper‐responsiveness through the modulation of vascular leakage and VEGF expression mediated by HIF‐1α/HIF‐2α signaling as well as IGF‐I action in allergic airway disease of mice.
Drug‐/radiation‐induced interstitial lung disease in the United Kingdom general population: Incidence, all‐cause mortality and characteristics at diagnosis
Authors: AMAR RAJEEV K. , JICK SUSAN S. , ROSENBERG DANIEL , MAHER TOBY M. , MEIER CHRISTOPH R. 
Published: May 2012

ABSTRACTBackground and objective:  Radiotherapy and an increasing number of substances are implicated in the pathogenesis of interstitial lung disease (ILD). While the frequency of published data on more common ILD entities such as the idiopathic interstitial pneumonias has increased in recent years, less attention has been given to relatively rarely occurring forms such as drug‐/radiation‐induced ILD.Methods:  Data from the UK‐based General Practice Research Database (GPRD) was used to estimate the incidence of drug‐/radiation‐induced ILD over a 12‐year period (1997–2008). Crude incidence rates were stratified by gender, age group and calendar period, and rate ratios were adjusted using Poisson regression. All‐cause mortality was modelled using Cox regression, and characteristics at diagnosis were compared with a random sample of matched, non‐ILD controls using conditional logistic regression.Results:  A total of 128 patients with an incident diagnosis of drug‐/radiation‐induced ILD were identified, and the overall incidence density during the study period was 4.1 (95% confidence interval 3.4–4.9) per million person‐years. Incidence rates increased during the time period 1997–2005 and decreased thereafter. The adjusted all‐cause mortality was >4 times higher in cases compared with controls.Conclusions:  This UK population‐based study characterizes patients diagnosed with drug‐/radiation‐induced ILD and quantifies incidence and all‐cause mortality during 1997–2008. No statistically significant time trend in incidence was found, despite having observed numeric increases in incidence rates during the study window. Future research using the GPRD and other data sources is required to better understand the disposition of patients diagnosed with drug‐/radiation‐induced ILD and to investigate potential trends incidence and mortality over time.
Influence of age on the clinical differentiation of atypical pneumonia in adults
Authors: MIYASHITA NAOYUKI , KAWAI YASUHIRO , AKAIKE HIROTO , OUCHI KAZUNOBU , HAYASHI TOSHIKIYO , KURIHARA TAKEYUKI , OKIMOTO NIRO 
Published: May 2012

ABSTRACTBackground and objective:  The Japanese Respiratory Society (JRS) scoring system is a useful tool for the early and simple presumptive diagnosis of atypical pneumonia (Mycoplasma pneumoniae and Chlamydia pneumoniae pneumonia). However, it has been suggested that it is difficult to diagnose atypical pneumonia in the elderly using this system. In the present study, we evaluated the accuracy and usefulness of the JRS scoring system for diagnosing atypical pneumonia in different age groups.Methods:  Cases of M. pneumoniae (n = 262), C. pneumoniae (n = 98) and common bacterial pneumonia (n = 364) were analysed.Results:  For both atypical pneumonias, the frequency of comorbid illnesses and being in a higher risk category were significantly greater in elderly (age ≥60 years) than in non‐elderly patients (age <60 years). One or more additional aetiological factors were more frequently present in elderly than in non‐elderly patients. The diagnostic sensitivity and specificity for atypical pneumonia were 39% and 88%, respectively, in the elderly group, and 86% and 88%, respectively, in the non‐elderly group. When the patients were stratified into 10‐year age groups, the diagnostic sensitivity was highest in the 18‐ to 29‐year age group and decreased from the youngest to the oldest age group.Conclusions:  These results indicate that it is difficult to distinguish between atypical pneumonia and bacterial pneumonia in the elderly using the JRS scoring system. When treating patients aged ≥60 years, physicians should use fluoroquinolones or β‐lactam antibiotics + macrolides as empirical first‐choice drugs so as to always provide antibiotic protection against potential atypical pathogens.