bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare gynecological entity: malignant cervical PEComa (perivascular epithelioid cell differentiation tumour) - challenges in diagnosis, treatment and surveillance
Authors: Anjos Amanda da Silva , Kwiatkowski Filipe Vieira , Kwiatkowski Rafael Vieira , Bonow Danielle Rediess , Vasques Luana Ferreira , Teixeira Sabine Triguero 
Published: May 2024

ABSTRACTPerivascular epithelioid cell tumors constitute a family of mesenchymal tumors characterized by the concomitant expression of melanocytic and muscular markers. Gynecological perivascular epithelioid cell tumors are rare, encompassing about 25% of cases. Studies demonstrate an even rarer occurrence in the uterine cervix. In this article, we report a case of malignant perivascular epithelioid cell tumors of the uterine cervix in a young patient, managed with total hysterectomy with unilateral salpingo- oophorectomy (due to suspected neoplasic involvement of the right ovary) and bilateral pelvic lymphadenectomy. Due to limited data, diagnosing these tumors is challenging. Given the uncertain biological behavior of this neoplasm, they should be considered potentially malignant and require long-term follow-up, despite the potential for late local recurrence and distant metastases. Surgical treatment involving complete resection of the lesion with clear margins remains the recommended option for this type of tumor until more consistent evidence can support adjuvant treatments.
Immunohistochemistry and next-generation sequencing for NTRK fusion detection in differentiated thyroid cancer of children, adolescents and young adults
Authors: Telles Ana Clara Oliveira Tosta , Machado Gabriel Jeferson Rodríguez , von-Ammon Juliana Lima , da-Matta Rafael Reis Campos , de-Oliveira Taíse Lima Cerqueira , de Lima Beltrão Fabyan Esberard , da-Paz Alexandre Rolim , Hecht Fabio , de Castro Lopes Guilherme , Rios Leonardo Freitas Boaventura , Lisboa Bruno da Silva , Ramos Helton Estrela 
Published: May 2024

ABSTRACT
Introduction: Pan-TRK immunohistochemistry staining can assess the protein expression from NTRK gene fusions. A little is known about its utility in differentiated thyroid cancer samples from children, adolescents, and young adults patients. Objective:Investigate pan-TRKimmunohistochemistry sensitivity and specificity in differentiated thyroid cancer samples from children, adolescents, and young adults patients.
Methods: Tumor samples obtained from 79 children, adolescents, and young adults patients (age <21 years) diagnosed with differentiated thyroid cancer between January, 2010 and January, 2021 were retrospectively recruited from four health centers from state of Bahia e Paraíba, Brazil. NTRK gene fusion testing of all archival FFPE tumor samples: pan-TRK immunohistochemistry staining for TRKA, TRKB and TRKC protein expression were performed and then analyzed with RNA-based nextgeneration sequencing assay to confirm immunohistochemistry pan-TRK result and elucidate fusion partner.
Results: Pan-TRK immunohistochemistry: 3 of 79 cases had positive pan-TRK expression: next-generation sequencing; 4 were identified with NTRK gene fusion, pan-TRK immunohistochemistry was negative in all 4 NTRK next-generation sequencing-positive cases. 25 of 79 NTRK next-generation sequencing-negative control cases had concordant negative pan-TRK immunohistochemistry results. Therefore, our rate of false positive pan-TRK immunohistochemistry results was 3/25 (12%). The overall results for pan-TRK immunohistochemistry in our cohort of next-generation sequencing-negative cases was: (i) sensitivity (0%), (ii) specificity (96%), (iii) positive predictive value (94.7%), (iv) negative predictive value (91%).
Conclusion: Pan-TRK immunohistochemistry was not a tissue-efficient screen for NTRK fusions in differentiated thyroid cancer from children, adolescents, and young adults patients. This is the largest cohort of from children, adolescents, and young adults differentiated thyroid cancer cases stained with pan-TRK immunohistochemistry, and it is the first to detail the sensitivity and specificity of pan-TRK immunohistochemistry regarding the data obtained by targeted RNA-based next-generation sequencing panel in differentiated thyroid cancer.
Himalayas farmer participatory evaluation of balanced application of nutrients in rice (Oryza sativa)–wheat (Triticum aestivum) system in Kumaon hills
Authors: DINESH KUMAR SINGH  , GAURAV DEEP SINGH  , ROHITASHAV SINGH  , A.P. SINGH  , SUMIT CHATURVEDI  , MOHAN SINGH  
Published: May 2024

A study was conducted by involving 24 farmers in their fields during 2011–13 in lower Kumaon hills, to study the response of rice (Oryza sativa L.)–wheat (Triticum aestivum L.) system to balanced nutrient application. The highest mean grain yields of rice (7.21 t/ha) and of wheat (5.14 t/ha) were recorded with the recommended doses of nitrogen, phosphorus and potassium (120, 60 and 40 kg/ha respectively, to both the crops) applied along with the sulphur @ 20 kg/ha followed by recommended NPK alone without micronutrients (7.01 and 5.01 t/ha, respec tively, for rice and wheat). During both the years, grain yields of rice and wheat under the farmers’ practice of nu trient application were significantly lower than the other treatments except control and N alone. In rice crop, appli cation of recommended doses of N, P and K provided additional mean grain yield of 1.50 t/ha over the farmers’ practice, whereas it was 1.04 t/ha in wheat. Application of sulphur @ 20 kg/ha over the recommended dose of NPK to both the crops resulted in additional grain yield of rice and wheat by 200 and 130 kg/ha, respectively, it also resulted in the highest production efficiency (45.4 kg/ha/day). The highest net returns were found under the treatment receiving recommended dose of NPK along with sulphur @ 20 kg/ha ( 150.15 × 103/ha) and it was 54.8% higher over the farmers’ practice of fertilizer application. The soil fertility status after harvesting of wheat in rice–wheat cropping system revealed that highest available nitrogen (298 kg/ha), phosphorus (16.9 kg/ha) and po tassium (200 kg/ha) were observed with recommended doses of N, P and K along with sulphur @ 20 kg/ha to rice and wheat crops in sequence.
Implementasi Undang-Undang Nomor 23 Tahun 2004 Tentang Penghapusan Kekerasan Dalam Rumah Tangga Persfektif Fiqh Siyasah Dusturiyah
Authors: Saidah Siagian  , John Kenedi  , Miti Yarmunida  
Published: May 2024

Penelitian ini untuk melihat implementasi Undang-undang Nomor 23 Tahun 2004 tentang Penghapusan Kekerasan Dalam Rumah Tangga persfektif fiqh siyasah dusturiyah (studi di kantor women’s crisis centre kota bengkulu). Dalam penelitian ini, jenis penelitian yang dipakai adalah penelitian hukum empiris dengan menggunakan pendekatan kualitatif yang bersifat dekriftif atau dengan kata lain sering disebut dengan penelitian lapangan (field research) atau menggunakan jenis penelitian empiris. Metode pengumpilan data menggunakan observasi, wawancara dan dokumentasi. Metode analisis data melalui tiga tahapan yaitu reduksi data, penyajian data dan verifikasi data. Penelitian ini menyimpulkan Kajian Fiqh Siyasah Dusturiyah terhadap Implementasi Undang-Undang Nomor 23 Tahun 2004 Tentang Penghapusan Kekerasan Dalam Rumah Tangga bahwa semua bentuk KDRT merupakan perbuatan aniaya yang mengganggu hak individu orang lain yang mengandung kemudaratan, bertentangan sekaligus prinsip mu’asyarah bi al-ma‟ruf yang diajurkan dalam berumah tangga untuk menuju keluarga yang sakinah, mawaddah, dan warahmah, dan mekanisme pelaksanaan kebijakan yang dilakukan pemerintah ialah dengan menggunakan Ijtihad Jama'i.
POLA ASUH ORANG TUA TERHADAP PERKEMBANGAN ANAK USIA 5-6 TAHUN
Authors: Nurilah  , Fajriani Evalina 
Published: May 2024

Pola asuh merupakan pola interaksi antara orang tua dengan anak, tentang bagaimana cara sikap ataupun perilaku orang tua ketika berinteraksi dengan anak, termasuk juga cara penerapan aturan, mengajarkan nilai atau norma, memberi perhatian beserta kasih sayang, dan menunjukkan sikap serta perilaku baik, sehingga dapat dijadikan panutan bagi anaknya. Setiap orang tua masing-masing memiliki cara yang berbeda untuk membesarkan anaknya, termasuk cara pola asuh. Akan tetapi, beberapa orang tua terkadang tidak menyadari pola asuh seperti apa yang mereka terapkan. Padahal, pola asuh merupakan bagian terpenting dalam membentuk tingkah laku dan kecerdasan anak. Perlakuan orang tua terhadap anak dapat memberikan kontribusi yang sangat besar pada kompetensi sosial, emosi, dan kecerdasan atau intelektual anak. Tujuan penelitian ini adalah untuk mengetahui gambaran pola asuh orang tua terhadap perkembangan anak usia 5-6 tahun di RA Nurul Hidayah. Jenis penelitian yang digunakan pada penelitian ini adalah penelitian kuantitatif yang menggunakan desain cross sectional yaitu jenis penelitian yang menekankan waktu pengukuran atau observasi data variabel independen dan dependen hanya satu kali dalam satu waktu. Variabel independen dalam penelitian ini adalah pola asuh orang tua dan variabel dependennya adalah perkembangan anak. Berdasarkan pola asuh orang tua menunjukkan bahwa terdapat 32 responden (86,4%) menerapkan pola asuh demokratis pada anak, 4 responden (10,9%) memberikan pola asuh permisif pada anak, dan 1 responden (2,7%) menerapkan pola asuh otoriter pada anak. Berdasarkan perkembangan anak menunjukkan bahwa 36 anak (97,3 %) mengalami perkembangan yang sesuai, sebanyak 1 anak (2,7 %) mengalami perkembangan yang meragukan, serta tidak ada anak yang mengalami perkembangan yang menyimpang (0%).
Progression des apprentissages dans l’acquisition de savoirs nécessaires à l’improvisation au clavier : le cas de Il Transilvano (1593-1609) de Girolamo Diruta
Authors: Falcone Fabio Antonio 
Published: May 2024

À travers l’analyse didactique de Il Transilvano (1593-1609) de Girolamo Diruta, cet article se propose de déterminer et de décrire la nature des savoirs mis à l’étude pour la construction de l’expertise en improvisation au clavier. Dans le but de saisir le projet didactique sous-jacent à la méthode pédagogique de Diruta, il s’agira ici d’interroger la conduite de la progression mise en place par l’auteur pour la construction de ces savoirs. L’hypothèse posée est que les savoirs savants sous-jacents aux pratiques étaient construits autour d’un corpus restreint de contenus noyaux, notamment les notions de consonance et de dissonance, de diminution et de mouvements. Ce à travers l’organisation, par le maître, de dispositifs didactiques divers visant l’appropriation, par l’élève de contenus d’enseignement et l’installation d’une mémoire du système didactique (Centeno 1995) qui permette à l’élève de construire de nouveaux savoirs à partir de « savoirs en train de se faire » (Centeno 1995, 135). Il en résulte une progression des apprentissages caractérisée par des éléments de gradualité — en l’espèce, donnée par une complexification du milieu (Brousseau 1998) au fur et à mesure que l’on progresse dans le traité, ce qui induit une prise de responsabilité croissante de l’élève dans la construction de l’expertise en improvisation. En outre, cette progression fait l’objet d’introductions d’éléments complémentaires, porteurs de contradictions apparentes dans la réalisation de la tâche. Plus précisément, ces éléments complémentaires sont liés aux différents genres musicaux présentés par Diruta, qui exigent une modification de la stratégie de résolution sans que les savoirs savants soient toujours explicités à l’avance dans la définition de la tâche proposée par le maître.
Quantitative indicators of the training of cadets of the Irkutsk Fire Technical School in 1968-1993.
Authors: Baranovskii Andrei Valer'evich 
Published: May 2024

The subject of the research of the scientific article is the peculiarities of the process of training firefighters on the basis of the Irkutsk Fire Technical School of the Ministry of Internal Affairs of the USSR during the period of activity of this educational institution from 1968 to 1993 on the territory of the Irkutsk region. In this publication, on the basis of previously unpublished and not introduced into scientific circulation archival materials, historical data on quantitative changes in the recruitment and training of cadets of the Irkutsk Fire Technical School during the period of their educational activities are investigated. The author considers the issues of organizing entry examinations for incoming applicants, notes significant events in the educational activities of cadets, and summarizes data on the number of specialists who have completed training. The article identifies the features of the educational process on the basis of the school, which allowed the formation of a professional staff of firefighters in the regions of Siberia and the Far East. The research methodology includes a concrete historical approach (M.V. Astakhov, I.D. Kovalchenko, V.F. Kolomiytsev, A.P. Pronstein, etc.), as well as generalization, comparison, synthesis, classification, concretization; analysis of archival documents, legislation and scientific literature; retrospective analysis; method of historical analogies. The novelty of this scientific article lies in the fact that during the scientific research, historical and pedagogical sources, archival data describing in detail the history of the formation and development of the cadet recruitment structure of the school, as well as a detailed report on the quantitative and qualitative indicators of graduates of the fire school by year of graduation were identified and summarized. The conducted research is of interest to a wide range of readers, since the study of the educational activities of the school, structural and organizational measures for the recruitment and graduation of firefighters is a very important component in the study of the formation and development of departmental education of the Ministry of Internal Affairs of the USSR in the territory of the Baikal region in the XX century. The list of heads of these structural divisions at the stage of formation and development of the Irkutsk Fire Technical School of the Ministry of Internal Affairs of the USSR is considered.
Fatores associados ao aleitamento materno na primeira hora de vida
Authors: Szymanski Jéssica Helena Lourenço , Figueiredo Francisco Winter dos Santos , Silva Adna Thaysa Marcial da , Puccia Maria Inês Rosselli 
Published: May 2024

Introdução: O aleitamento materno na primeira hora de vida ainda é pouco estimulado em vários hospitais do Brasil. Objetivo: Analisar a prevalência e os fatores associados ao aleitamento materno na primeira hora de vida (AMP) entre recém-nascidos a termo. Métodos: Estudo transversal, de natureza quantitativa, com coleta de dados secundários retrospectivos em prontuários hospitalares de 250 recém-nascidos a termo, independentemente do tipo de parto, com histórico de gestacional de risco habitual, atendidos nos últimos seis meses anteriores ao período de coleta de dados, em uma maternidade pública da Grande São Paulo. Os dados foram coletados entre novembro de 2018 e janeiro de 2019, por meio de roteiro estruturado, mediante aprovação do hospital e do Comitê de Ética em Pesquisa da FMABC (Parecer n.º 2.924.393). O banco de dados e o tratamento estatístico foram realizados através do programa STATA®. Para a análise, utilizou-se proporções e teste qui-quadrado, adotando-se um nível de significância de 5% e 95% o intervalo de confiança. Resultados: A prevalência de AMP foi de 66%. O AMP está associado a anestesia no parto (p<0,001), APGAR menor ou igual a 8 no 1º e 5º minutos (p<0,001) e ao parto cesárea (p<0,001), cuja proporção na amostra foi de 29,2%. Desconforto respiratório (38,82%), hipotonia (24,70%), seguido de condições maternas desfavoráveis (18,82%), mostraram-se como fatores impeditivos para o AMP, embora 90% dos recém-nascidos tenham recebido Apgar 9/10 no 5º minuto. Conclusão: A prevalência do aleitamento materno precoce é inferior ao recomendado, porém compatível com as proporções de frequência nacional mais recentes.
The Chronic Time Pressure Inventory: further assessment of factorial structure and validity
Authors: Denovan Andrew , Dagnall Neil , Drinkwater Ken 
Published: May 2024

Background
Chronic time pressure represents a prevalent concern within modern society, and effective measurement is crucial for research advancement. The Chronic Time Pressure Inventory (CTPI) has thus far demonstrated adequate psychometric properties. However, only two studies have examined the measure and evidence of its validity is limited. Accordingly, the current investigation, via two independent studies, assessed the factorial composition and validity (convergent/discriminant) of the CTPI.

Methods
Study 1 (N = 398) examined competing factorial models and validity in relation to the Big Five personality traits (Extraversion, Agreeableness, Conscientiousness, Neuroticism, Openness). Study 2 (N = 358) replicated the analysis of factor structure and assessed validity in comparison with five time perspectives (Past Negative, Present Fatalistic, Future, Past Positive, Present Hedonistic). Participants across both studies completed standardized self-report measures capturing the variables.

Results
Comparison of confirmatory factor analysis (CFA) and exploratory structural equation modelling (ESEM) factor solutions indicated that an ESEM bifactor model provided the strongest data-model fit. This included a general chronic time pressure component alongside specific subfactors of Feeling Harried and Cognitive Awareness of Time Shortage. All scale items reflected the general factor; however, some items loaded weakly on the intended specific factor. The CTPI is thus a robust indicator of chronic time pressure but needs refinement as a measure of the specific factors. Convergent/discriminant validity analyses inferred that the CTPI captured chronic time pressure as a related, but distinct, construct to perceived stress, and evidenced a relationship with theoretically associated constructs (Big Five personality traits and time perspective). Overall, the CTPI is a sound measure of chronic time pressure and has the potential to further cohesive research efforts on the contribution of this construct to various life domains.
Effect of Various Weed Management Options on Weed Dry Matter, Yield Attributes and Yield of Sweet Corn (Zea mays L. saccharata) under Organic Production System
Authors: Neha . , Bhambri M. C. , Manisha . , Verma Nagendra Kumar , Porte Dipendra Pankaj , Kumar Harendra , Nag Anchal 
Published: May 2024

A field experiment was conducted at Instructional cum Research Farm, Indira Gandhi Krishi Vishwavidyalaya, Raipur (C.G.) during kharif 2019 entitled “Effect of various weed management options on weed dry matter, yield attributes and yield of sweet corn (Zea mays L. saccharata) under organic production system”. The soil of the experimental site was clayey in texture, neutral in reaction and low in nitrogen, medium in phosphorus and high in potassium. The experiment was laid out in Randomized Block Design with three replications. The weed flora of the experimental site was dominated by Echinocloa colona, Alternanthera sessilis, Parthenium hysterophorus, Cyperus iria. Results revealed that the highest green cob yield of sweet corn was recorded in stale seed bed + reduced spacing (upto 25%) + mulching with paddy straw + 20 DAS hand weeding (7.63t ha-1 ) which was 83.48% higher than the weedy check. The green cob yield in stale seed bed + reduced spacing (upto 25%) + mulching with paddy straw + 20 DAS hand weeding was found to be at par with mulching with waste polythene bags (ITK-practices) (7.45t ha- ), hand weeding twice carried out at 20 and 40 DAS (7.33 t ha-1) and soil solarization with 25µ polythene mulch during summer + one hand weeding at 20 DAS(6.94t ha-1). Although grain yield in other weed management practices was significantly lower than stale seed bed + reduced spacing (upto 25%) + mulching with paddy straw + 20 DAS hand weeding treatments but higher than weedy check. Similarly, As regards total weed dry weight at harvest, the total lowest weed dry weight was observed in stale seed bed + reduced spacing (upto 25%) + mulching with paddy straw + hand weeding at 20 DAS(3.45gm-2) followed by mulching with waste polythene bags (ITK- practices)(4.71 gm-2), hand weeding at 20 and 40 DAS (4.96gm-2)and soil solarization with 25µ polythene mulch during summer + one hand weeding at 20 DAS(5.08 gm-2). However, higher WCE was noticed in these treatment over weedy check. The weedy check was significantly inferior in all the yield attributes and green cob yield of sweet corn.
Prevalence of African Mosaic and Morphological Characterization of Cassava (Manihot esculenta Cranz) Varieties in Two Agroecological Zones of Cameroon
Authors: Alain Heu , Bertrand Mboussi Serge , Abdou Kone Nsangou Nourou , Sylvere Dida Lontsi Landry , Patrice Ngoh Dooh Jules , Zachee Ambang 
Published: May 2024

The objective of this work is to conduct an epidemiological study of African cassava mosaic and to characterize the diversity of local cultivars in circulation in the monomodal and bimodal rainforest zones of Cameroon. Disease-related parameters (incidence and severity index) were studied as well as morphological parameters (plant height, leaflet color, petiole color, lobe length, number of lobes, number of branches, petiole length). The results show that 96 cassava varieties were identified with 89 local varieties and 07 improved varieties. Diseased plants showed a symptom severity index of 1 to 5, which could reduce production by half in the areas considered. The leaf color was dark green, the number of branches was 3, the lobe and petiole lengths were 16.46 and 22 cm respectively, while the number of lobes was 5 the disease incidence for the two agro-ecological zones as a whole is 57.58% for a symptom severity index of 3. The epidemiological study reveals that the desease incidence of both agro-ecological zones was 57.58 % for a symptom severity index of 2 corresponding to 40 %. In the humid forest zone with monomodal spray the average incidence was 49.74% and a leaf attack rate was 29.03 % in the locality of Njombé (Cameroon's littoral region). At Ekona in southwestern Cameroon, the average incidence was 63% and leaf attack index was 1 corresponding to 20 %. In the bimodal rainforest zone (central Cameroon region), the average incidence was 60 % for a leaf attack rate was 37.11%. The expected results highlight a relatively worrying situation. Principal Component Analysis (PCA) confirms the convergence of tolerance towards the mosaic and grouped the different varieties into more or less homogeneous groups according to the morphological and epidemiological cassava descriptors. The results of the present work show that the introduction of cassava local varieties tolerant to mosaic disease in middling could be an alternative for the control of the cassava mosaic disease.
Improved adaptive control for the discrete‐time parametric‐strict‐feedback form
Authors: González Graciela Adriana 
Published: November 2009

AbstractAdaptive control design for a class of single‐input single‐output nonlinear discrete‐time systems in parametric‐strict‐feedback form is re‐visited. No growth restrictions are assumed on the nonlinearities. The control objective is to achieve tracking of a reference signal. As usual, the algorithm derives from the combination of a control law and a parameter estimator (certainty equivalence principle). The parameter estimator strongly lies on the regressor subspace identification by means of an orthogonalization process. Certain drawbacks of previous schemes are analyzed. Several modifications on them are considered to improve the algorithm complexity, control performance and numerical stability. As a result, an alternative control scheme is proposed. When applied to the proposed class of systems, global boundedness and convergence remain as achieved objectives while improving the performance issues of previous schemes. Copyright © 2009 John Wiley & Sons, Ltd.