bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are Eco-Neighborhoods Health-Promoting Places? Case Study of ZAC Boucicat and ZAC Frequel-Fontarabe in Paris
Authors: TROJANOWSKA Monika 
Published: February 2025

Abstract
Eco-neighborhoods are constructed to answer the call to protect our planet, our common home. They were first initiated as a grassroots initiative by eco-enthusiast, and gradually adopted as national or regional strategies. Various methods for certification and labeling were created by international institutions and national governments which evaluate ecological, economical, and societal aspects of their design and functioning. The recognized gap in knowledge concerns the development of health-promoting places within eco-neighborhoods. In this paper, a comparative study of two small certified eco-neighborhoods in Paris – ZAC Boucicaut and ZAC Frequel-Fontarabe is presented. These neighborhoods were assessed with the universal standard for health-promoting places. The results suggest that within eco-neighborhoods it is possible to care for ecological aspects without compromising on health-promoting places.
Influence of land use activities on predicted soil loss in a semi-arid river basin
Authors: Singh Vikram Gaurav , Kumar Nirmal , Acharki Siham , Singh Sudhir Kumar , Kulimushi Luc Cimusa , Olusola Adeyemi Oludapo , Choudhari Pandurang , Rawat Kishan Singh , Jodhani Keval H. , Gupta Nitesh , Omar Padam Jee 
Published: February 2025

ABSTRACT
Soil loss due to land transformations is a serious issue confronting the globe nowadays. The research's main focus was to predict future land use and land cover (LULC) and quantify soil loss, which is exacerbated by excessive rainfall following uneven topography, intensive agriculture, and a lack of adequate watershed management strategies. The Landsat satellite data were classified using maximum likelihood algorithm, and future LULC (2030 and 2040) was quantified using TerrSet Land Change Modeler through Markov Chain Model. In addition, the RUSLE was applied to estimate soil loss based on LULC data from various years, and the results were evaluated using sediment observation data. In this research, the LS-factor has been quantified by employing open-source digital elevation models (DEMs) (SRTM, ASTER, MERIT, AW3D30, NASADEM, CARTOSAT, and TanDEM-X). Furthermore, hypsometry analysis was carried out to assess erosion vulnerability at the sub-watershed. The results showed that SRTM 30-m DEM-based soil loss corresponds to observation. Moreover, soil loss is estimated at 16.55 t/ha/year for 2015, whereas future soil loss may be reduced to 14.51 and 14.46 t/ha/year in 2030 and 2040, respectively.
The Role of Immunosenescence and Inflammaging in the Susceptibility of Older Adults to SARS-CoV-2 Infection
Authors: Zia Aliabbas , Sahebdel Faezeh , Farkhondeh Tahereh , Pourbagher-Shahri Ali Mohammad , Samini Fariborz , Samarghandian Saeed 
Published: February 2025

Abstract:
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 coronavirus that is
one of the most significant challenges to public health over the past few years. Most people
are vulnerable to SARS-CoV-2, but older adults are more vulnerable. Aging is one of the major
risk factors for the detrimental consequences of COVID-19, likely due to chronic inflammation
and immunosenescence, both of which are the characteristics of old age. Immunosenescence
refers to the weakening of the immune system with age while inflammaging describes
the low-grade chronic inflammation seen in older individuals. One key aspect of human
aging is immune deficiency. During aging, our body’s defense system weakens, resulting
in decreased responses to infection by novel pathogens and a reduced ability to become immunized.
The presence of chronic inflammation and viral infection in old age may cause several
adverse unpredictable outcomes increasing the propensity and severity of the disease and
requires to be considered, enabling people to better prepare for the potential consequences of
this ongoing pandemic. This requires consideration so that individuals can better be prepared
to address the potential consequences of this ongoing pandemic. In this review, we discuss the
clinical characteristics of elderly COVID-19 patients and survey the associated molecular
pathways that are pivotal for the interactions of the coronavirus and host cellular responses,
including immunosenescence, inflammation, telomere attrition, impaired autophagy, mitochondrial
dysfunction and alterations in major aging signaling pathways, which are crucial for
the discovery of new therapeutic and preventive methods in the ongoing pandemic.
Association of Hypertensive Disorders of Pregnancy and their Clinical Features with Peripartum Cardiomyopathy: A Systematic Review and Meta-analysis
Authors: Huang Wilbert , Syahruddin Siti Shofia , Johansyah Alexandra Aurelia , Suriadiredja Siti Saqinah , Santoso Dhanny Primantara Johari , Sasotya RM Sonny , Azis Muhammad Alamsyah , Pribadi Adhi , Prameswari Hawani Sasmaya 
Published: February 2025

Background:
Peripartum Cardiomyopathy (PPCM) is a rare yet fatal cardiac disease
associated with pregnancy. PPCM has been shown to have similar etiopathogenesis with hypertensive
disorders of pregnancy (HDP). Hence, this study aims to study the association between
HDP and the development of PPCM.

Methods:
Three databases (PubMed, Scopus, Cochrane Library) were searched and screened
based on prespecified inclusion and exclusion criteria. Predictors of PPCM evaluated were HDP
(preeclampsia, superimposed preeclampsia, chronic hypertension, and gestational hypertension)
and its clinical features (severe preeclampsia, age, parity, serum creatinine, etc.). Data were analyzed
using the random effects model of pooled odds ratios (ORs) with the Mantel Haenszel
method, and publication bias was assessed with a funnel plot.

Results:
A total of 13 observational studies with 11,951 PPCM cases from 7 countries were
identified. All types of HDP were associated with significantly increased odds of developing
PPCM, and severe preeclampsia was associated with the highest OR of 13.33 (CI: 5.95 – 29.83,
p < 0.01). Additionally, superimposed preeclampsia, chronic hypertension, preeclampsia, and
lastly gestational hypertension were associated with increased odds of PPCM with OR 5.77,
4.73, 4.70, and 3.13, respectively. Other clinical features being statistically significant for
PPCM development included advanced age > 35 years and multiple pregnancies (p < 0.05). No
significant difference in creatinine level was found between PPCM and no PPCM group. No
publication bias was found based on funnel plot assessment.

Conclusion:
HDP, especially severe preeclampsia, is associated with increased odds of PPCM
development; hence, a low threshold for PPCM screening in this high-risk group is required.
Novel Drug Delivery for Treating Cartilage Injuries
Authors: Dortaj Hengameh , Zakizadeh Fatemeh , Izadi Sepideh , Dehghan Mehdi , Pourentezari Majid , Dortaj Sareh , Rajabi Ali 
Published: February 2025

Abstract:
Osteochondral injuries caused by trauma or osteoarthritis are joint diseases that impose significant social and economic burdens on modern society. The mechanisms of articular cartilage healing pose a crucial clinical challenge. Delivering cells and therapeutic factors to the injury site using various types of carriers is a novel approach that promotes tissue regeneration. Multiple factors are involved in the cartilage regeneration process; however, uncontrolled delivery of drugs, growth factors, and other mechanisms may not only diminish the full repair potential of damaged cartilage but also lead to undesirable morphological effects. New approaches, such as targeted smart drug de-livery, may enhance the therapeutic potential of intra-articular agents by prolonging the half-life of selected drugs within the joint and specific tissues. This review will discuss the roles of various bio-logics in cartilage regeneration, as well as different delivery methods for achieving effective healing responses.
Analysis of Carbapenemase and Extended-Spectrum Beta-Lactamases- producing Cephalosporin-resistant Strain of Escherichia coli and Klebsiella pneumoniae among Children in a Tertiary Care Centre, South India
Authors: Thattil Santhosh J. , Ajith Thekkuttuparambil A. , Dhanaraj Suresh 
Published: February 2025

Background:
The incidence of Extended-Spectrum Beta-Lactamase (ESBL)- and carbapenemase-producing enterobacteriaceae in enterobacterales is increasing globally, pos-ing a threat to health. Schoolchildren under adolescence show a gradual increase in immunity, and respiratory infections like pneumonia and others are more prevalent in children under five-years of age. However, gastrointestinal disorders primarily affect children under one-year of age.

Aims:
The study aimed to analyze the Extended-spectrum Beta-Lactamase (ESBL) and car-bapenemase-producing cephalosporin-resistant strain of Escherichia coli and Klebsiella pneumoniae, isolated from various specimens of hospitalized children below ten years of age.

Methods:
A cross-sectional study on laboratory reports of positive culture specimens from children below ten years of age was conducted to analyze the cephalosporin-resistant strains of E. coli and K. pneumoniae between July, 2023 and July, 2024 in the Microbiology depart-ment of a tertiary care hospital central Kerala, South India. The cephalosporin-resistant strain was analyzed for carbapenemase or ESBL presence using a double disc synergy test. The data were subjected to statistical analysis.

Results:
A total of 1636 culture reports were analyzed, and growth was found in 672 (41%) specimens. Among the cephalosporin-resistant 187 strains (66%), E. coli and K. pneumoniae were 106 (57%) and 81 (43%), respectively. A significant difference (p <0.05) was noted between cephalosporin-resistant and sensitive E. coli among the various age groups. The dif-ference between cephalosporin-resistant and susceptible K. pneumoniae across different age groups, however, was negligible (p>0.05). Carbapenemase and ESBL-producing E. coli and K. pneumoniae were 39%, 29%, and 48%, respectively. The carbapenemase and ESBL-pro-ducing strains were more in children below one year. An insignificant difference (p>0.05) between ESBL (+) and ESBL (-) E. coli or K. pneumoniae was found among various age groups. A similar observation was found between carbapenemase [+] and carbapenemase (-) E. coli or K. pneumoniae. According to the effect value (Cramer's V) determined for each comparison, the association was either very weak or negligible.

Conclusion:
The cephalosporin-resistant strains (66%) of E. coli and K. pneumoniae were 57% and 43%, respectively. Specimens of children below one year of age showed more inci-dence of ESBL-producing K. pneumonia (67%) and carbapenemase-producing E. coli (68%).
Environmental and Economic Impacts of End-tidal Control of Volatile Anesthetics: A Scoping Review and Analysis
Authors: Beard John W. , Kennedy R. Ross , Philip James H. , Erslon Mary , Jiao Weiqi , Hyatt Hayden W. , Yapici Halit O. 
Published: February 2025

Objective
This review aimed to assess the environmental and economic impacts of End-tidal Control (ET control) compared to manual clinician administration of inhaled anesthetics.

Methods
A scoping literature review was conducted to evaluate the consumption of anesthetic agents when using the Et Control software medical device compared to standard care (manual clinician adjustments) and the associated environmental/economic outcomes. Data were pooled across studies, and standardized mean difference, non-standardized weighted mean difference, and relative reduction in anesthetic agent usage between Et Control and manual adjustments were calculated. Annual reductions in hospital costs and greenhouse gas emissions for a representative 592-bed academic medical center were calculated.

Results
Eight out of the ten identified studies demonstrated that Et Control reduced anesthetic agent usage rates compared to manual administration. Based on the compiled evidence, Et Control results in a mean decrease of anesthetic agent usage by 32.2% for desflurane, 30.1% for isoflurane, and 4.1% for sevoflurane. The annual cost-savings and environmental impact for a large academic medical center using Et Control instead of manual administration is conservatively estimated to be $95,536 ($16,136 per 100 beds), with greenhouse gas emissions reduced by 434,345 kg (73,360 per 100 beds) in CO2 equivalencies (~100 motor vehicle emissions annually).

Conclusion
Our focused review and analysis indicate that Et Control reduces greenhouse gas emissions of anesthesia practice while also conferring cost-savings. The ability of semi-closed loop anesthesia systems to facilitate low-flow anesthesia warrants the need for future research to understand the full scope of environmental and economic impacts.
Developing a Smart Sensing Sock to Prevent Diabetic Foot Ulcers: Qualitative Focus Group and Interview Study
Authors: Corser Jenny , Yoldi Irantzu , Reeves Neil D , Culmer Pete , Venkatraman Prabhuraj D , Orlando Giorgio , Turnbull Rory Peter , Boakes Paul , Woodin Eric , Lightup Roger , Ponton Graham , Bradbury Katherine 
Published: February 2025

Background
Diabetic foot ulcers are common and costly. Most cases are preventable, although few interventions exist to reliably support patients in performing self-care. Emerging technologies are showing promise in this domain, although patient and health care provider perspectives are rarely incorporated into digital intervention designs.

Objective
This study explored patient and health care provider feedback on a smart sensing sock to detect shear strain and alert the wearer to change their behavior (ie, pause activity and check their feet) and considered how patient experience and attitudes toward self-care are likely to impact uptake and long-term effective engagement with the device to curate guiding principles for successful future intervention development.

Methods
This qualitative study combined semistructured interviews and a focus group alongside a participant advisory group that was consulted throughout the study. In total, 20 people with diabetic neuropathy (n=16, 80% with history of diabetic foot ulcers) and 2 carers were recruited directly from podiatry clinics as well as via a recruitment network and national health mobile app for one-to-one interviews either in person or via landline or video call. A total of 6 podiatrists were recruited via professional networks for 1 virtual focus group. Participants were asked about their experience of diabetic foot health and for feedback on the proposed device, including how it might work for them in daily life or clinical practice. The data were analyzed thematically.

Results
Three main themes were generated, each raising a barrier to the use of the sock complemented by potential solutions: (1) patient buy-in—challenged by lack of awareness of risk and potentially addressed through using the device to collect and record evidence to enhance clinical messaging; (2) effective engagement—challenged by difficulties accepting and actioning information and requiring simple, specific, and supportive instructions in line with podiatrist advice; and (3) sustained use—challenged by difficulties coping, with the possibility to gain control through an early warning system.

Conclusions
While both patients and podiatrists were interested in the concept, it would need to be packaged as part of a wider health intervention to overcome barriers to uptake and longer-term effective engagement. This study recommends specific considerations for the framing of feedback messages and instructions as well as provision of support for health care providers to integrate the use of such smart devices into practice. The guiding principles generated by this study can orient future research and development of smart sensing devices for diabetic foot care to help optimize patient engagement and improve health outcomes.
Die „Gymnastik des Allgemeinen“: (moralische) Bildung in der ökonomischen Sphäre.
Authors: Dummer Niklas , Müller Johanna , Prix Lea 
Published: February 2025

Der Artikel diskutiert Hannes Kuchs Kritik an der in liberalen Gerechtigkeitstheorien vertretenen Annahme, dass ökonomisches Verhalten leitende und politisch-moralische Normen getrennt voneinander zu betrachten sind. Gegen diese Annahme argumentiert Kuch in seiner Studie „Wirtschaft, Demokratie und liberaler Sozialismus“ dafür, dass die ökomische Sphäre eine zentrale Rolle für die Ermöglichung und Verwirklichung demokratischer Gerechtigkeit spielt. Dabei problematisiert Kuch, dass die ökonomische Sphäre in ihrer gegenwärtigen Gestalt einen überwiegend negativen Einfluss auf die moralische Bildung der Subjekte hat. Hieran anknüpfend attestiert Kuch der politischen Sphäre ein normatives Primat, während er der ökonomischen Sphäre ein empirisches Primat hinsichtlich der moralischen Bildung der Subjekte zuschreibt. Die KommentatorInnen kritisieren Kuchs Position dahingehend, dass sie einen problematischen Gegensatz zwischen einer amoralischen ökonomischen Sphäre und einer idealisierten moralischen politischen Sphäre postuliert. Neben einem binnenlogisch-argumentativen Problem erweist sich diese Darstellung insbesondere hinsichtlich der Analyse real-politischer und global-ökonomischer Machtverhältnisse als problematisch. Die KommentatorInnen plädieren daher für eine differenziertere Analyse, die die moralische Ambivalenz der beiden Sphären und ihre moralisch bildenden und destruktiven Potenziale anerkennt.
Islet Transplantation Versus Standard of Care for Type 1 Diabetes Complicated by Severe Hypoglycemia From the Collaborative Islet Transplant Registry and the T1D Exchange Registry
Authors: Rickels Michael R. , Ballou Cassandra M. , Foster Nicole C. , Alejandro Rodolfo , Baidal David A. , Bellin Melena D. , Eggerman Thomas L. , Hering Bernhard J. , Kandeel Fouad , Brand Adam , Miller Kellee M. , Barton Franca B. , Payne Elizabeth H. 
Published: February 2025

OBJECTIVE
Islet transplantation was recently US Food and Drug Administration approved for adults with type 1 diabetes complicated by recurrent severe hypoglycemia events (SHEs). We sought to understand the long-term benefit for glycemic control and risk of immunosuppression to kidney function associated with islet transplantation compared with ongoing standard of care.

RESEARCH DESIGN AND METHODS
We performed a case-control analysis of prospectively collected data from patients in the Collaborative Islet Transplant Registry (CITR) with at least one SHE in the year (2000–2014) before transplantation (cases) and compared them with data from patients in the T1D Exchange (T1DX) Registry with at least one SHE in the year (2010–2012) before enrollment (controls), with both cohorts observed over 5 years. SHEs were restricted to those resulting in seizure or loss of consciousness.

RESULTS
Cases from CITR (n = 71) compared with controls from T1DX (n = 213) more often achieved the primary outcome of HbA1c &lt;7.0% and absence of an SHE (71–80 vs. 21–33% over 5 years; P &lt; 0.001) and the outcome of HbA1c ≤6.5% and absence of an SHE (60–75% vs. 10–20%; P &lt; 0.001) while requiring significantly less insulin (majority in CITR were insulin independent). Kidney function, measured by estimated glomerular filtration rate, declined from baseline to a greater extent in CITR than in T1DX (−8.8 to −20 vs. −1.3 to −6.5 mL ⋅ min−1 ⋅ 1.73 m−2 over 5 years; P &lt; 0.001).

CONCLUSIONS
Islet transplantation for adults with type 1 diabetes complicated by SHEs results in near-normal glycemic control in the absence of SHEs more often than observed with standard of care, but at the cost of greater reduction in kidney function.
Переосмысление романтического образа идеального мира в позднем творчестве Э. Т. А. Гофмана (на примере новеллы "Datura Fastuosa")
Authors: Королева В.В. , Притомская А.Р. 
Published: February 2025

В статье исследуется трансформация романтического образа идеального мира в новелле Э. Т. А. Гофмана «Datura Fastuosa». Утверждается, что в позднем творчестве немецкого писателя возникает реалистический образ идеального мира, ставший результатом переоценки писателем идеи о романтическом идеале, который теперь лишается сказочного элемента, а также имманентной связи с творческим началом человека. Для создания образа идеального мира Гофман прибегает к приему романтического контраста, включающего в себя оппозиции: «экзотический юг – Германия», «страсть – семейная идиллия», «старость – молодость», «филистерские материальные блага – духовные ценности», «рациональное постижение природы – чувственное постижение природы». Делается вывод о том, что идеальный мир в позднем творчестве немецкого романтика лишен эстетики экзотического, а его достижение лежит не через искусство, а через романтическую любовь и интеграцию чувственного и рационального подхода к постижению природы как Логоса.
The article examines the transformation of the romantic image of the ideal world in E. T. A. Hoffmann's short story "Datura Fastuosa". It is argued that in the late work of the German writer there is a realistic image of the ideal world as the result of the writer's reassessment of the idea of the romantic ideal, which is now deprived of a fabulous element, as well as the immanent connection with the creative principle of the human being. To create an image of the ideal world Hoffmann uses the technique of romantic contrast, including the opposition: ‘exotic south – Germany’, ‘passion – family idyll’, ‘old age – youth’, ‘philistine material goods – spiritual values’, ‘rational comprehension of nature – sensual comprehension of nature’. It is concluded that the ideal world in the late work of the German Romantic is devoid of the aesthetics of the exotic, and its achievement lies not through art, but through romantic love and the integration of sensual and rational approach to the comprehension of nature as Logos.
Художественные концепты «Письмо» в прозе А. С. Пушкина и “Letter” в романах Дж. Остин
Authors: Соловьева Е.Е. 
Published: February 2025

Письменная коммуникация была важной частью европейской бытовой культуры XVIII–XIX вв., что нашло отражение в художественной литературе эпохи. В статье рассматриваются художественные концепты «Письмо» в прозе А. С. Пушкина и “Letter” в романах Дж. Остин – писателей, связанных общей культурно-исторической эпохой и литературным контекстом европейской психологической прозы. Общее ядро концепта не заслоняет специфики, обусловленной разностью социальных отношений в России и Англии, а также особенностями индивидуального мировосприятия и стиля.
Correspondence was an important part of the everyday culture in Europe of the XVIII–XIX centuries, which was reflected in the fiction of this period. The article compares the artistic concepts of “Pismo” in A. S. Pushkin’s prose and “Letter” in J. Austin’s novels. These writers relate to a common cultural and historical epoch and the literary context of European psychological prose. The common core of the concept does not obscure the specifics caused by the difference in social relations in Russia and England, as well as the peculiarities of individual worldview and style.