bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of the Manifestation of Sensitivity to Justice in the Structure of the Worldview of High School Students
Authors: Бурмако А.К. 
Published: April 2024

Рассмотрены теоретические проблемы реакции старшеклассников на несправедливость. Показаны место и особенности проявления чувствительности к справедливости в структуре мировоззрения старшеклассников. Представлены результаты опроса, которые выявили индивидуально-психологические особенности и различия в проявлении чувствительности к справедливости у юношей и девушек. Сформулированы рекомендации по учету особенностей чувствительности к справедливости у юношей и девушек для педагогов и психологов.
Theoretical problems of high school students’ reaction to injustice are considered. The place and features of the manifestation of sensitivity to justice in the structure of the worldview of high school students are shown. The results of the survey are presented, which revealed individual psychological characteristics and differences in the manifestation of sensitivity to justice in boys and girls. Recommendations have been formulated for teachers and psychologists to take into account the peculiarities of sensitivity to justice in boys and girls.
Approaches to Using the Works of S.V. Rachmaninoff in Teaching Chinese Pianists
Authors: Ли И. 
Published: April 2024

Обоснована актуальность проблемы подготовки пианистов в Китае, способных предлагать объективные исполнительские трактовки произведений С.В. Рахманинова. Приведены результаты анализа исследований, посвященных творчеству композитора. Определена цель исследования – разносторонне изучить личность и творчество С.В. Рахманинова, его фортепианное наследие в контексте становления и развития китайской фортепианной педагогики. Выделены основные направления и задачи исследования. Результаты проводимого исследования позволят подготовить квалифицированных, творческих исполнителей, которые смогут оказать влияние на китайскую молодежь – студентов музыкальных учебных заведений и многомиллионную слушательскую аудиторию.
The relevance of the problem of training pianists in China who are capable of offering objective performance interpretations of S.V.’s works is substantiated. Rachmaninov. The results of an analysis of studies devoted to the composer’s work are presented. The purpose of the study was determined – to comprehensively study the personality and creativity of S.V. Rachmaninov, his piano heritage in the context of the formation and development of Chinese piano pedagogy. The main directions and objectives of the research are highlighted. The results of the ongoing research will make it possible to prepare qualified, creative performers who will be able to influence Chinese youth – music students and a multimillion-dollar listening audience.
In Vitro Effects of Chlorhexidine and Isopropyl Alcohol Conditioning Agents on Immediate and Late Bond Strength of Fiber Posts to Dentin
Authors: Emami Arjomand Mansoureh , Nasoohi Negin , Shabani Mohaddeseh 
Published: April 2024

Objectives: This study assessed the effect of chlorhexidine (CHX) and isopropyl alcohol (IA) on immediate and late pushout bond strength (PBS) of fiber posts to dentin.
Materials and Methods: In this in vitro study, 54 single-canal premolars were endodontically treated, and randomly assigned to 3 groups (N=18) for root dentin conditioning with distilled water (control), 2% CHX, and 70% IA after post space preparation. Fiber posts were cemented with TheraCem self-adhesive cement, and each group was subdivided into two subgroups (N=9) for PBS measurement immediately after bonding, and after 5000 thermal cycles (5-55°C). The roots were then sectioned, and their PBS was measured. The mode of failure was evaluated under a stereomicroscope at ×40 magnification. Data were analyzed by repeated measures ANOVA and Tukey’s test (alpha=0.05).
Results: The highest PBS was noted in the IA group (21.12 MPa) after 24 hours and the lowest PBS belonged to the control group after thermocycling (7.48 MPa). The immediate and post-thermocycling PBS were significantly lower in the control group than the CHX group (P<0.05). The PBS in both the control and CHX groups was lower than that in the IA group (P<0.001). Regardless of the type of detergent, a significant reduction in PBS was observed after thermocycling (P<0.003). The PBS significantly decreased from the cervical towards the apical region in all groups (P<0.001).
Conclusion: According to the results, application of IA before the self-adhesive cement effectively improved the immediate and late PBS, and was significantly more effective than CHX.
Exploring the Catalytic Activity and Hydrogen Peroxide Sensing Abilities of Low-Density Silica Nanoparticles: Synthesis and Analysis
Authors: kaliyaperumal viswanathan , kaliyaperumal Chitra Priya , rajasekaran Srilekha , ramasamy Radha perumal 
Published: April 2024

Abstract

In this study, low density silica nanoparticles (LDS) were synthesized and used as a heterogeneous catalyst for dye removal and nanosensors for hydrogen peroxide detection. Organosilane silica nanoparticles were produced and calcinated at 400°C to produce low density particles. SEM, FTIR, DLS, and zeta potential analysis were used to characterize the generated particles. The results confirmed that the particle size, charge, and density varied with the APTES concentration. The results showed that at lower APTES concentrations, small particles (70-75 nm) were created, but at higher concentrations, larger particles (420-430 nm) were produced. The particle density changed depending on the APTES content. The UV absorption spectra of APTES-added samples varied significantly between 440 and 480 nm.The dye removal activity was measured using crystal violet dye; under UV irradiation, the particles destroyed up to 90% of the dye within 120 minutes, and the kinetics were also detailed. HRP-coated LDS was used as a nanosensor for detecting H2O2. Results indicated linearity of 5´10-10 ~ 1´10-5 (M) (R2=0.995), and a detection limit of 5 nm mol. The milk was spiked with H2O2 at varied concentrations and used as detections for the actual sample analysis. Finally, this paper describes the simplest way for producing tailored low-density silica, which is ideal for biomedical and drug delivery applications..
Research on Tunnel Control Surveying and Penetration Error Accuracy Estimation for High Speed Railway
Authors: Sun Qingjuan , Ma Haitao , Zhang Guihao 
Published: April 2024

Abstract
The magnitude of the penetration error is critical in determining whether a high-speed railway tunnel project can effectively break through as per the project's predictions. Controlling the lateral penetration error is essential in managing the overall penetration error. Estimating the accuracy of the penetration error based on control measurement results and conducting penetration measurements after evaluation are effective measures to ensure the quality of tunnel projects. Taking the first-level risk tunnel of Luojiashan in the ZWZQ-7 section of Zhengwan High-speed Rail as an example, this paper explores methods for laying out control points outside and inside the tunnel based on measurement specifications, aiming at controlling the penetration error limit. It also discusses data processing techniques using different software and estimating tunnel penetration error accuracy based on control measurement results.
Reduction in vertical transmission rate of Bean common mosaic virus in bee-pollinated common bean plants
Authors: Mhlanga Netsai M. , Pate Adrienne E , Arinaitwe Warren , Carr John P. , Murphy Alex M. 
Published: April 2024

Abstract

Vertical transmission, the transfer of pathogens across generations, is a critical mechanism for the persistence of plant viruses. The transmission mechanisms are diverse, involving direct invasion through the suspensor and virus entry into developing gametes before achieving symplastic isolation. Despite the progress in understanding vertical virus transmission, the environmental factors influencing this process remain largely unexplored. We investigated the complex interplay between vertical transmission of plant viruses and pollination dynamics, focusing on the common bean (Phaseolus vulgaris). The intricate relationship between plants and pollinators, especially bees, is essential for global ecosystems and crop productivity. We explored the impact of virus infection on seed transmission rates, with a particular emphasis on the bean common mosaic virus (BCMV), bean common mosaic necrosis virus (BCMNV), and cucumber mosaic virus (CMV). Under controlled growth conditions, BCMNV exhibited the highest seed transmission rate, followed by BCMV and CMV. Notably, bee-pollinated BCMV-infected plants outdoors showed a reduced transmission rate compared to self-pollinated plants. This highlights the influence of pollinators on virus transmission dynamics. The findings provide valuable insights into the species-specific nature of virus seed transmission and underscore the importance of considering environmental factors, such as pollination, in understanding and managing plant virus spread.
Hypoxia-induced OSBPL10 accelerates pancreatic cancer progression through CNBP sequestration
Authors: Huang Yishu , Zhang Ronghao , Fan Shuyang , Shi Minmin , Tang Xiaomei , Wang Xinjing , Deng Xiaxing 
Published: April 2024

Abstract

Purpose Given oxysterol binding protein like 10’s (OSBPL10) known involvement in lipid transport and oncogenic activity in other tumors, we aimed to elucidate the mechanism underlying its contribution to pancreatic cancer progression.
Methods We employed data from the Gene Expression Omnibus database. A series of assays, including CCK8,colony formation,wound healing and transwell, were conducted to assess the impact of OSBPL10 on the proliferation and metastatic capacities of pancreatic cancer cells. Flow cytometry was employed to evaluate the influence of OSBPL10 on macrophages. Co-immunoprecipitation , mass spectrometry, and western blot assays were utilized to investigate the potential mechanisms of OSBPL10 activity.
Results The study revealed a significant uoregulation of OSBPL10 in pancreatic cancer cells, correlating with poor prognosis. OSBPL10 knockdown attenuated pancreatic cancer cells proliferation and metastasis, while its overexpression enhanced these malignant behaviors. Notably, OSBPL10 knockdown promoted the transformation of M2 macrophages into M1 macrophages in the pancreatic cancer microenvironment. Mechanistically, hypoxia-induced upregulation of OSBPL10 through interaction with hypoxia-inducible factor 1-α in the promoter region was identified. Additionally, OSBPL10 directly bound to CNBP, mediating CNBP expression and ultimately regulating the proliferation and metastasis capacity of pancreatic cancer cells, as well as influencing macrophage polarization.
Conclusions This study provides comprehensive insights into oncogenic role of OSBPL10 in pancreatic cancer, uncovering key mechanisms involving hypoxia, HIF-α,and CNBP. The finding suggest that OSBPL10 plays s crucial role in promoting pancreatic cancer progression, making it a potential therapeutic target for intervention in this malignancy.
Mapping burn severity in the Bejaia region, Algeria (2021), using Landsat 8 satellite data on the GEE platform
Authors: Sallaye Miloud , Belloulou Bilal , Khallef Boubaker 
Published: April 2024

Abstract

In the recent past, Forest fires are a severe environmental risk that occurs continually in the Mediterranean region. The province of Bejaia, located in the northeastern part of Algeria, is an illustrative example of forest fires. In this research, we used multi-source remote sensing data (MODIS and Landsat 8) and the Google Earth Engine (GEE) platform to assess the impact of forest fires in August 2021. In addition, the Differenced Normalized Difference Vegetation Index (dNDVI) and Differenced Normalized Burn Ratio (dNBR) were employed to identify fire-affected areas and estimate the degree of damage. Our results showed that 2.24% of the study area experienced high fire severity, covering 7223 hectares. This high fire sensitivity is probably due to topographic and environmental factors. This study demonstrates how Geographic Information System (GIS) and remote sensing can be valuable tools for forest managers, helping them make better decisions for sustainable forest management.
Qualitative research on nutritional literacy in patients with type 2 diabetes—Patient and health worker perspectives
Authors: zhang wenjuan , Xia Yinglan , Sun Ziyu , Wu Yuhong 
Published: April 2024

Abstract

Background
Medical nutritional therapy is the basis of the treatment of type 2 diabetes mellitus. To deeply explore the nutritional literacy status and influencing factors of type 2 diabetes mellitus patients, to understand the nutritional needs of patients, and to provide a basis for strengthening the nutritional literacy level of diabetes mellitus patients in China, improving self-management, and improving the quality of life.
Methods
A phenomenological research method was used to conduct semi-structured interviews with 13 patients with type 2 diabetes mellitus and 10 healthcare professionals, and the Colaizzi 7-step method was used to analyze the data and refine the themes.
Results
Four themes and 12 sub-themes were summarized: lack of beliefs about nutrition management (ambiguity about the role of nutrition management, lack of willingness to gain in-depth knowledge about nutrition, lack of awareness of dietary nutritional risks, and poor dietary nutritional adherence); insufficient knowledge and skills in nutrition management (misconceptions about nutritional knowledge, lack of skills in nutritional combinations and food exchanges, and insufficient ability to cope with difficulties); and insufficient ability to interact with nutritional information (active less access to nutritional knowledge, limited utilization of perceived surrounding resources, transformation and utilization of nutritional information); and insufficient ability to critique nutritional information (difficulty in identifying nutritional information, selective acceptance of nutritional information).
Conclusion
The overall nutritional literacy of patients with type 2 diabetes mellitus is insufficient, the perception of nutritional management is weak, nutritional knowledge and skills are more lacking, the interactive and critical ability of nutritional information needs to be improved, and the patients are unable to carry out effective disease management; therefore, it is necessary for healthcare professionals to improve the nutritional literacy of the patients for the self-management and healthy outcomes by targeting the weak points.
Clinicopathological characterization of subgroups in anti-glomerular basement membrane nephritis patients From a Single Center in China: A 12-Year observational study
Authors: Fang Kun , Wang Rui , Ding Yan , Zhou Wenxv , Zhou Zheren , Wei Ting , Yang Yi , Feng Jie 
Published: April 2024

Abstract

Background
Despite the previous reports of patients with combined anti-glomerular basement membrane (anti-GBM) disease occurring sequentially or simultaneously with other nephropathies, most of them have been reported seperately. The complication of these diseases is rare and the mechanism is not clear, and their immuno-antibodies, microscopic picture, clinical presentation, treatment and prognosis are different, therefore, we presented the collection of anti-GBM with combined disease such as membranous nephropathy (MN), anti-neutrophil cytoplasmic antibody (ANCA), IgA nephropathy and atypical anti-GBM to systematically characterized the epidemiological features, clinical manifestations, pathological features and herapeutic outcomes through a summative review.
Method
We retrospectively a case series of 39 anti-GBM diseases from a single center in Northwest China from 2011–2023.
Results
A total of 39 patients with anti-GBM disease including 19 males and 20 females were collected with a mean age of 50.0 ± 14.6 years. Among them there were 22 cases (22/39,56.4%) of anti-GBM alone, 6 cases (6/39,15.4%) of combined ANCA, 6 cases (6/39,15.4%) of combined MN, 2 cases (2/39,5.1%) of combined IgAN, and 3 cases (3/39,7.7%) of atypical anti-GBM nephropathy. The mean duration of the disease was 2.6 ± 6.2 months. Clinical symptoms were dominated by fever 68.2% (15/22), oliguria/anuria 63.6% (14/22), and microscopic haematuria 88.9% (16/22,) in the anti-GBM alone group, and nausea and vomiting 50% (3/6) in the anti-GBM + MN group, and edema 83.3% (5/6) in the anti-GBM + MN group. The proportion of patients requiring hemodialysis (HD) at the first visit was 79.5% (31/39) in all patients, 56.4% (22/39) in the anti-GBM alone group, 66.7% (4/6) in the anti-GBM + ANCA group, 66.7% (4/6) in the anti-GBM + MN group, and 100% (2/2) in the anti-GBM + IgAN group. Among them, 56.4% had more than 85% glomerular involvement. The proportion of sclerotic glomeruli was higher in the anti-GBM and anti-GBM + ANCA groups. The highest percentage of cellular crescents was found in the anti-GBM group as long with fibrous crescents in the anti-GBM + ANCA group. Immunofluorescence staining demonstrated positive IgG and C3 staining in all subgroups.
Conclusions
We concluded that the complication of other nephritis is another potential risk factor for anti-GBM, which is directly attributable to the adverse effects of the different immune depositions and pathological features on renal function, as timely intervention in patients with different pathological features is crucial.
The Impact of the Wingate Test on Anaerobic Power in the Lower Limbs of Athletes with Varied Time and Load
Authors: Liu Ying , Yan Juntao , Gong Zhigang , Liu Qi 
Published: April 2024

Abstract

This study investigates the effects of Wingate anaerobic test (WAnT) on anaerobic capacity(AC) at different time (20s, 30s, 40s, 45s) and resistance load (7.5%BM, 8.5%BM, 9.5%BM, 10.5%BM).12 male runners of 200m、400m were subjected to four wingate tests of different times and loads.The changes of AC and lower limb muscle characteristics were analyzed by WAnT and electromyography.The result shows that the IEMG, RMS%, MPF and AC of lower limb muscles of RF，BF，VM，VL，TA and LG were increased by time (P < 0.05 or P < 0.01), but there was no significant difference in IEMG of MG (P > 0.05). Load significantly increased AC, IEMG, RMS% and MPF of lower limb muscles (P < 0.01). The interaction effect of time and load had no significant difference on PP, MP, RPE, IEMG, RMS% and MPF (P > 0.05), but increased on FI (P < 0.05).In conclusion, for 200m and 400m athletes, it is recommended to use a combination of 20s and 10.5%BM load to achieve optimal peak power and training effect,as well as a combination of 20s and 9.5%BM load for better average power and training effect.
Differential bioaccumulation patterns of heavy metals and organochlorine pesticides in the Northern Shoveler and Northern Pintail (Avian: Anatidae) related to blood parameters and body condition
Authors: Muñoz Sarahi Roos , Acevedo Edgar Cruz , Castillo-Guerrero Alfredo , Torres-Bugarin Olivia , Río-Zaragoza Oscar Basilio del , García-Hernandez Jaqueline , Aguilar-Zarate Gabriela , Danemann Gustavo D. , Lozano Miguel Betancourt 
Published: April 2024

Abstract

Organochlorine pesticides (OCP) and heavy metals are contaminants that threaten ecosystem health. Migratory birds can bioaccumulate these contaminants; therefore, contaminant effects should be assessed during reproductive, migratory, and wintering stages. We assessed Hg, Pb, and OCPs in the Northern Shoveler (Spatula clypeata) and Northern Pintail (Anas acuta) during their winter stay in southern Sinaloa, Mexico, evaluating associations with exposure and the effects on health-status biomarkers. These migratory ducks use a wide variety of sites in the central and western United States, Canada, and Alaska and along the Mexican portion of the eastern Pacific Flyway. Spatula clypeata showed significantly higher concentrations of Hg in feathers compared to those found in A. acuta. Although there were no differences between species in feather Pb concentrations, the concentrations were high, indicating widespread Pb contamination in wetlands along migratory routes. Compared to those of A. acuta, S. clypeata exhibited lower condition index values, higher organosomatic index values, a higher degree of Hg and OCP bioaccumulation, and a higher OCP liver/muscle ratio. Both species showed similar associations between OCP and Pb concentrations and high spleensomatic index values. Neither species exhibited a relationship between contaminants and the heterophile/lymphocyte ratio or budcells in polychromatic erythrocytes. Our results indicate that both species, despite coexisting along their migratory routes and in their wintering habitat, likely have different bioaccumulation profiles due to differences in trophic niches.
An expert rule-based approach for identifying infantile-onset Pompe disease patients using retrospective electronic health records
Authors: Rustamov Jaloliddin , Rustamov Zahiriddin , Mohamad Mohd Saberi , Zaki Nazar , Tenaiji Amal Al , Harbi Mariam Al , Jasmi Fatma Al 
Published: April 2024

Abstract

Pompe disease (OMIM #232300), a rare genetic disorder, leads to glycogen buildup in the body due to an enzyme deficiency, particularly harming the heart and muscles. Infantile-onset Pompe disease (IOPD) requires urgent treatment to prevent mortality, but diagnosis is often delayed by inadequate newborn screening (NBS) methods or the unavailability of these methods. Our study aims to streamline IOPD diagnosis in the UAE using electronic health records (EHRs) for faster, more accurate detection and timely treatment initiation. This study utilized electronic health records from the Abu Dhabi Healthcare Company (SEHA) healthcare network in the UAE to develop an expert rule-based screening approach operationalized through a dashboard. The study encompassed six diagnosed IOPD patients and screened 93,365 subjects. Expert rules were formulated to identify potential high-risk IOPD patients based on their age, particular symptoms, and creatine kinase levels. The proposed approach was evaluated using accuracy, sensitivity, and specificity. The proposed approach accurately identified five true positives, one false negative, and four false positive IOPD cases. The false negative case involved a patient with both Pompe disease and congenital heart disease. The focus on CHD led to the overlooking of Pompe disease, exacerbated by no measurement of creatine kinase. The false positive cases were diagnosed with Mitochondrial DNA depletion syndrome 12-A (SLC25A4 gene), Immunodeficiency-71 (ARPC1B mutation), Niemann-Pick disease type C (NPC1 gene mutation leading to frameshift), and Group B Streptococcus meningitis. The proposed approach of integrating expert rules with a dashboard facilitated efficient data visualization and automated patient screening, which aids in the early detection of Pompe disease. Future studies are encouraged to investigate the application of machine learning methodologies to enhance further the precision and efficiency of identifying patients with IOPD.