bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lyme Borreliosis During Pregnancy
Authors: Lakos András , Solymosi Norbert 
Published: March 2012

AbstractOne of the authors (AL) presented a poster on 34 pregnancies of maternal Lyme borreliosis (Lb) in 1995. It was striking that untreated Lb associated with higher probability of adverse outcome but the number of patients were small and the statistical power was low. We have recently published a paper on 95 maternal Lb and the outcome of their pregnancies. Since the closure of the database for that manuscript the number of the pregnant women with Borrelia infection observed in our Centre increased to 124, and the statistical analysis strengthened our previous doubtful observations and reached significant results in important aspects by now. This series is the largest study to date on this topic. Treatment was administered parenterally to 87 (70%) women and orally to 25 (20.0%). Infection remained untreated in 12 (10%) pregnancies. Adverse outcomes were seen in 7/87 (8%), 9/25 (36%), 8/12 (67%), of the parenterally, orally treated and untreated women, respectively. In comparison to patients treated with antibiotics, untreated women had a significantly higher risk of adverse pregnancy outcomes (OR: 11.62, p<0.001). Mothers treated orally comparing to iv. treatment had an increased chance (OR: 6.28) to have an adverse outcome (p=0.001). In the adverse pregnancy outcome, the most impressive difference was between the untreated and parenterally treated women (OR: 21.44, p<0.001). The probability of adverse outcome increased by the exposition time (from the first maternal symptom to the treatment or delivery). When the exposition time has reached four months, the probability of adverse outcome increased by 33%. We had no chance to examine the bacterial invasion of the foetus. Loss of the pregnancy (N=9), small for gestational age or preterm birth (N=7) were the most prevalent adverse outcomes in our series. The other complications were heterogeneous. Our results indicate that untreated or orally treated maternal Borrelia burgdorferi s.l. infection is associated with adverse outcomes. 'Congenital Lyme disease' similar to the Hutchinson's triad in syphilis is unlikely.
FAIRE-seq data analysis of Chlamydomonas reinhardtii under carbon deprivation
Authors: Urbina-Gómez David , Vischi Winck Flavia , Müller-Röber Bernd , Riaño-Pachón Diego Mauricio 
Published: March 2012

AbstractFor the genome-wide identification of nucleosome depleted regions under carbon deprivation, we analyze an available set of data from an assay of formaldehyde-assisted isolation of regulatory elements followed by sequencing (FAIRE-seq). Mapping to the sequenced nuclear genome of C.reinhardtii, followed by the identification of the enrichment-sequenced fragments was performed. We examined the location of these fragments relative to annotated genes. The related genes were associated to the corresponding Gene-Ontology (GO), for an evaluation of over-representate GO categories. Some genes, link with functions or locations, that have been previous described, indicating the success of the method finding carbon-metabolism related fragments.
Rotenone Persistence Model for Montane Streams
Authors: Brown Peter J. , Zale Alexander V. 
Published: March 2012

AbstractThe efficient and effective use of rotenone is hindered by its unknown persistence in streams. Environmental conditions degrade rotenone, but current label instructions suggest fortifying the chemical along a stream based on linear distance or travel time rather than environmental conditions. Our objective was to develop models that use measurements of environmental conditions to predict rotenone persistence in streams. Detailed measurements of ultraviolet radiation, water temperature, dissolved oxygen, total dissolved solids (TDS), conductivity, pH, oxidation–reduction potential (ORP), substrate composition, amount of organic matter, channel slope, and travel time were made along stream segments located between rotenone treatment stations and cages containing bioassay fish in six streams. The amount of fine organic matter, biofilm, sand, gravel, cobble, rubble, small boulders, slope, pH, TDS, ORP, light reaching the stream, energy dissipated, discharge, and cumulative travel time were each significantly correlated with fish death. By using logistic regression, measurements of environmental conditions were paired with the responses of bioassay fish to develop a model that predicted the persistence of rotenone toxicity in streams. This model was validated with data from two additional stream treatment reaches. Rotenone persistence was predicted by a model that used travel time, rubble, and ORP. When this model predicts a probability of less than 0.95, those who apply rotenone can expect incomplete eradication and should plan on fortifying rotenone concentrations. The significance of travel time has been previously identified and is currently used to predict rotenone persistence. However, rubble substrate, which may be associated with the degradation of rotenone by adsorption and volatilization in turbulent environments, was not previously considered.
Beyond the fringe? South African social movements and the politics of redistribution
Authors: Friedman Steven 
Published: March 2012

Collective action in support of the redistribution of wealth and power in South Africa was initially led by the trade union movement. But, as more labour-market entrants have failed to find work in the formal economy, unions' capacity to speak for the poor has declined. Scholars and activists have, therefore, come to see new social movements as a superior source of effective action for redistribution. Analysis reveals that the movements are not equipped to lead a redistributive coalition but that co-operation between unions and social movements, and a synergy between their approaches, is most likely to produce effective redistributive politics.
[Au-delà des bords? Les mouvements sociaux sud-africains et la politique de redistribution]. L'action collective en faveur de la redistribution des richesses et du pouvoir en Afrique du Sud était initialement dirigée par le mouvement syndical. Mais, compte tenu du fait que des nouveaux arrivants dans le marché d'emploi n'ont pas réussi à trouver du travail dans l'économie formelle, la capacité des syndicats de parler au nom des pauvres a diminué. Les universitaires et les activistes sont, par conséquent, arrivés à voir de nouveaux mouvements sociaux comme une source supérieure d'une action efficace pour la redistribution. L'analyse révèle que les mouvements ne sont pas équipés pour mener une coalition de redistribution, mais la coopération entre les syndicats et les mouvements sociaux, et une synergie entre leurs approches, est plus susceptible de produire des politiques efficaces de redistribution.

Mots-clés: redistribution; politiques; mouvements sociaux; syndicats; Afrique du Sud
Emotional support and counselling for people with visual impairment: Quantitative findings from a mixed methods pilot study
Authors: Barr Wally , Hodge Suzanne , Leeven Martina , Bowen Louise , Knox Paul 
Published: March 2012

AbstractAims: This paper reports on mainly quantitative findings from a mixed methods evaluation of a new model of emotional support and counselling for people with moderate visual impairment. Method: The CORE Outcome Measure was completed with service users at baseline and post‐intervention to assess the impact of the new service on psychological wellbeing and social functioning. Their perceived needs and expectations of the service were also explored. Results: Of the 35 individuals providing data at each assessment time, mean item scores on the CORE fell significantly (p<.001), taking the sample from within a clinical population before therapy, to a mean score below this following therapy. A more positive outlook accompanied this improvement in functioning. Discussion: Findings from the study augment the growing evidence that emotional support and counselling services can play an important role alongside and within related vision services. Implications for practice: The study indicates that therapeutic input for the visually impaired client group may need to target both wellbeing (feelings about oneself and the future) and problems (depression, anxiety, physical health, and trauma). Conclusions: Our findings suggest that a dual model of emotional support and counselling offers considerable benefit for people with visual impairment.
Policy Diffusion and Innovation: Media and Experts in Colorado Recreational Water Rights
Authors: Crow Deserai A. 
Published: March 2012

Abstract
Beginning in 1998, an innovation in water rights policy took place in Colorado. This paper analyses the diffusion of the recreational in-channel water right policy innovation among Colorado communities. This research involved in-depth case studies in 12 Colorado communities. Data include interviews, legal and legislative documents, and mass media coverage. These new water rights spread among Colorado communities through two processes. First, experts acted as information entrepreneurs providing both technical and policy information to other communities. Through repetitive journalistic sourcing, media coverage spread the influence and reputation of certain experts who then influenced internal policy decisions in subsequent communities.
Reflections on Implementation Science
Authors: Gopalakrishnan Chennat , Okada Norio 
Published: March 2012

Abstract
This paper provides an original formulation of some of the key issues that we think are central to the effective implementation of integrated disaster risk management (IDRM). We tentatively call this focused effort “implementation science”. We define the term implementation science, in this context as a collective enterprise to develop a systematic body of knowledge (facts, empirical evidence, intuitions, insights, experience) on the causes and consequences of natural and human disasters, to analyse them systematically, and to successfully implement the resulting strategies in the prevention or mitigation of losses due to disasters. With this in view, we have identified and discussed in this paper some key elements of implementation science in the context of disaster management, both natural and man-made, based on a comprehensive review of important research and writing in the disaster management field.
Food Security of the Hill Tracts of Chittagong in Bangladesh
Authors: Majumder S. , Bala B.K. , Hossain M.A. 
Published: March 2012

Abstract
This paper presents the status of food security of the Hill Tracts of Chittagong in Bangladesh and the factors affecting household food security. Data were collected from primary and secondary sources and a multi-stage sampling was designed for selecting the farm households. A quantitative method is used for computation of food security at upazila (sub-district) level. Multiple logit regression models are fitted to the data on food security of the farmers to identify the factors affecting food security at household level. Overall status of food security at upazila level is good for all the upazilas except Rangamati Sadar. Logit analysis shows that household food security is significantly affected by farm size, types of inhabitants, professions and crops cultivated. Logit analysis also shows that transition from jhum to horticulture is significantly influenced by farm size, education and distance to market. It is concluded that transition from jhum to horticulture enhances food security.
The Impact of Financial Incentives on the Composition of Long‐term Care in Norway
Authors: Øien Henning , Karlsson Martin , Iversen Tor 
Published: March 2012

AbstractIn Norway, municipalities have economic incentives for choosing residential care in nursing homes for high‐income clients and home‐based care for low‐income clients. Using a three‐year panel, 2007‐2009, on 427 municipalities we provide an analysis of the effect of the Norwegian long‐term care (LTC) financing system on the composition of LTC services at the municipality level. Our main result is that the composition of service is determined by local government revenue and local need for LTC services. We cannot identify an effect of average income among older people in a municipality regarding the balance between home‐based care and nursing home care. Hence, the results do not provide evidence of a service distortion.
1001 Proteomes: a functional proteomics portal for the analysis of Arabidopsis thaliana accessions
Authors: Joshi Hiren J. , Christiansen Katy M. , Fitz Joffrey , Cao Jun , Lipzen Anna , Martin Joel , Smith-Moritz A. Michelle , Pennacchio Len A. , Schackwitz Wendy S. , Weigel Detlef , Heazlewood Joshua L. 
Published: March 2012

Abstract
Motivation: The sequencing of over a thousand natural strains of the model plant Arabidopsis thaliana is producing unparalleled information at the genetic level for plant researchers. To enable the rapid exploitation of these data for functional proteomics studies, we have created a resource for the visualization of protein information and proteomic datasets for sequenced natural strains of A. thaliana.
Results: The 1001 Proteomes portal can be used to visualize amino acid substitutions or non-synonymous single-nucleotide polymorphisms in individual proteins of A. thaliana based on the reference genome Col-0. We have used the available processed sequence information to analyze the conservation of known residues subject to protein phosphorylation among these natural strains. The substitution of amino acids in A. thaliana natural strains is heavily constrained and is likely a result of the conservation of functional attributes within proteins. At a practical level, we demonstrate that this information can be used to clarify ambiguously defined phosphorylation sites from phosphoproteomic studies. Protein sets of available natural variants are available for download to enable proteomic studies on these accessions. Together this information can be used to uncover the possible roles of specific amino acids in determining the structure and function of proteins in the model plant A. thaliana. An online portal to enable the community to exploit these data can be accessed at http://1001proteomes.masc-proteomics.org/
Contact: jlheazlewood@lbl.gov
Supplementary information: Supplementary data are available at Bioinformatics online.
ADMIT: a toolbox for guaranteed model invalidation, estimation and qualitative–quantitative modeling
Authors: Streif Stefan , Savchenko Anton , Rumschinski Philipp , Borchers Steffen , Findeisen Rolf 
Published: March 2012

Abstract
Summary: Often competing hypotheses for biochemical networks exist in the form of different mathematical models with unknown parameters. Considering available experimental data, it is then desired to reject model hypotheses that are inconsistent with the data, or to estimate the unknown parameters. However, these tasks are complicated because experimental data are typically sparse, uncertain, and are frequently only available in form of qualitative if–then observations. ADMIT (Analysis, Design and Model Invalidation Toolbox) is a MatLabTM-based tool for guaranteed model invalidation, state and parameter estimation. The toolbox allows the integration of quantitative measurement data, a priori knowledge of parameters and states, and qualitative information on the dynamic or steady-state behavior. A constraint satisfaction problem is automatically generated and algorithms are implemented for solving the desired estimation, invalidation or analysis tasks. The implemented methods built on convex relaxation and optimization and therefore provide guaranteed estimation results and certificates for invalidity.
Availability: ADMIT, tutorials and illustrative examples are available free of charge for non-commercial use at http://ifatwww.et.uni-magdeburg.de/syst/ADMIT/
Contact: stefan.streif@ovgu.de
Improvement of Sponge Cake Baking Test Procedure for Simple and Reliable Estimation of Soft White Wheat Quality
Authors: Choi Hyun‐Wook , Harris Tracy , Baik Byung‐Kee 
Published: March 2012

ABSTRACTThe sponge cake baking test is accepted and routinely used as a standard quality evaluation tool of soft white wheat for Asian markets, but its lengthy and laborious procedure makes it unsuitable for the routine evaluation of a large number of wheat breeding lines. We simplified the sponge cake baking procedure in the egg‐whipping step and improved its consistency by replacement of the hand mixing of cake batter with mechanical mixing, using a wire whisk or a BeaterBlade paddle. Egg whipping and mechanical batter mixing conditions were optimized by comparing foam density, sponge cake volume, and crumb grain to those obtained by the conventional procedure. Foam density, sponge cake volume, and crumb grain comparable to the conventional 100 g flour procedure were obtained with modifications, including extension of whipping time without heat input using a 5 L KitchenAid mixer, one‐time water addition at 3 min before the completion of egg whipping instead of twice, as in the conventional procedure, and cake batter mixing with a KitchenAid wire whisk or a BeaterBlade paddle. For baking a 50 g flour cake, egg foam of appropriate density was obtained with increased whipping speed and shortened egg‐whipping time (8 min). The modified sponge cake baking procedure yielded egg‐foam density, cake volume, and crumb grain similar to the conventional procedure and effectively differentiated soft wheat flours of different quality. Sponge cake volume of 14 soft white wheat flours ranged from 1,134 to 1,426 mL with the conventional procedure, from 1,113 to 1,333 mL with the modified procedure of batter mixing with a wire whisk, from 1,108 to 1,360 mL with the modified procedure of batter mixing with a BeaterBlade paddle, and from 577 to 719 mL with the modified method of 50 g of flour and batter mixing with a wire whisk. The modified methods with the BeaterBlade paddle and wire whisk exhibited significant correlation in cake volume with a conventional procedure (r = 0.931, P < 0.001 and r = 0.925, P < 0.001, respectively).
Seasonal diet and prey selection of black‐backed jackals on a small‐livestock farm inSouthAfrica
Authors: Kamler Jan F. , Klare Unn , Macdonald David W. 
Published: March 2012

AbstractThe extent to which black‐backed jackals (Canis mesomelas) selectively consume domestic sheep (Ovis aries) compared to wild prey is unknown. Using faecal analysis and prey surveys, we determined the seasonal diet and prey selection of jackals on a small‐livestock farm inSouthAfrica. Sheep comprised 25–48% of the biomass consumed by jackals across seasons, and consumption peaked during the lambing seasons, indicating sheep often were the main food resource for jackals. Another main food resource was wild ungulates <50 kg, primarily springbok (Antidorcas marsupialis) and steenbok (Raphicerus campestris), which comprised 8–47% of the biomass consumed. Other important food items were mammals 1–3 kg (4–16%), which included hares (Lepusspp.) and springhares (Pedetes capensis), and small rodents (10–14%). Compared to the biomass available, jackals selectively consumed mammals 1–3 kg over sheep across all seasons, whereas wild ungulates <50 kg were selectively consumed over sheep in most seasons. Our results showed that jackals selectively consumed different food items throughout the year and that wild prey were consistently selected over sheep.
Randomised clinical trial: enteral nutrition does not improve the long‐term outcome of alcoholic cirrhotic patients with jaundice
Authors: Dupont B. , Dao T. , Joubert C. , Dupont‐Lucas C. , Gloro R. , Nguyen‐Khac E. , Beaujard E. , Mathurin P. , Vastel E. , Musikas M. , Ollivier I. , Piquet M.‐A. 
Published: March 2012

SummaryBackgroundMalnutrition and jaundice are independent prognostic factors in cirrhosis.AimTo assess the impact of enteral nutrition on the survival of alcoholic cirrhotic patients with jaundice but without acute alcoholic hepatitis.MethodsThe study was a multicentre prospective randomised controlled trial comparing effects of enteral nutrition vs. a symptomatic support in patients with alcoholic cirrhosis and jaundice (bilirubin ≥51 µmol/L) but without severe acute alcoholic hepatitis. A total of 99 patients were randomised to receive either the conventional symptomatic treatment (55 patients) or the symptomatic support associated with 35 kcal/Kg/day of enteral nutrition during 4 weeks followed by an oral nutritional support during 2 months (44 patients). Randomisation was stratified on nutritional status. One‐year survival curves were compared using the Kaplan–Meier method and Logrank test.ResultsPopulations in both arms were similar. One‐year survival was similar in the overall population (27/44 patients (61.4%) in the enteral nutrition arm vs. 36/55 (65.5%) in the control arm; Logrank P = 0.60) and in the subgroup suffering from malnutrition [18/29 patients (62.1%) in the enteral nutrition arm vs. 20/32 (62.5%) in the control arm; Logrank P = 0.99]. There was no statistical difference for bilirubin, prothrombin rate, Child‐Pugh score, albumin or nutritional assessment. Complications during treatment (bleeding, encephalopathy, infection) occurred in 23% of patients in the enteral nutrition group (10/44) vs. 16% (9/55) of the control patients (P = 0.59).ConclusionEnteral nutrition does not improve the survival and hepatic or nutritional parameters of cirrhotic patients with jaundice.
The impact of pre‐operative focused transthoracic echocardiography in emergency non‐cardiac surgery patients with known or risk of cardiac disease
Authors: Canty D. J. , Royse C. F. , Kilpatrick D. , Williams D. L. , Royse A. G. 
Published: March 2012

SummaryThis prospective observational study investigated the effect of focused transthoracic echocardiography in 99 patients who had suspected cardiac disease or were ≥ 65 years old, and were scheduled for emergency non‐cardiac surgery. The treating anaesthetist completed a diagnosis and management plan before and after transthoracic echocardiography, which was performed by an independent operator. Clinical examination rated cardiac disease present in 75%; the remainder were asymptomatic. The cardiac diagnosis was changed in 67% and the management plan in 44% of patients after echocardiography. Cardiac disease was identified by echocardiography in 64% of patients, which led to a step‐up of treatment in 36% (4% delay for cardiology referral, 2% altered surgery, 4% intensive care and 26% intra‐operative haemodynamic management changes). Absence of cardiac disease in 36% resulted in a step‐down of treatment in 8% (no referral 3%, intensive care 1% or haemodynamic treatment 4%). Pre‐operative focused transthoracic echocardiography in patients admitted for emergency surgery and with known cardiac disease or suspected to be at risk of cardiac disease frequently alters diagnosis and management.