bluuebunny/crossref_metadata_2025_split huggingface dataset:
Postmenopausal Sexuality in Thai Women*
Authors: Tungphaisal Somchai , Chandeying Verapol , Sutthijumroon Sonthit , Krisanapan Oermporn , Udomratn Pichet 
Published: August 2010

AbstractWe evaluate sexuality in 100 natural menopausal women as pertains to hormones, symptoms related to intercourse, and marital relationship with sexual desire, orgasm and coital frequency. The mean age was 56.8 years while menopausal age was 50.3 years. The postmenopausal syndrome presented 55.0% occurring 1 to 7 years after menopause (mean 3.4 years). The common sexual problems after menopause were loss of libido, orgasmic dysfunction, and dyspareunia. Both sexual desire and activity decreased when compared with premenopausal period. Ninety percent of the subjects had sexual desire less than once a month. Only 14% of the subjects occasionally reached orgasm while the other 86% never had orgasm after menopause. The levels of FSH, LH, estradiol and testosterone were also reported. There was no correlation of hormone estradiol and testosterone, symptoms related to intercourse and marital relationship with sexual desire, orgasm, or coital frequency.
Plasma Vitamin A and Carotene in Maternal and Cord Blood
Authors: Ibrahim Khushnaseeb , Hassan Talat J. , Jafarey Sadiqua N. 
Published: August 2010

AbstractMean plasma vitamin A and carotene levels in 200 pregnant women at term were 30.3 mcg% and 43.6 mcg%. Sixty‐four percent of women had vitamin A in lower limit of normal (<33 mcg%) and 26% had deficient and low levels of carotene.Mean values of plasma vitamin A and carotene in cord blood was 13.7 mcg% and 16.5 mcg%, respectively, and lower than that of maternal blood at term.Women who had adequate levels of vitamin A (>33 mcg%) in blood had significantlyhigher intake of vitamin A. Similarly the newborn babies of those mothers who had adequate levels of vitamin A had significantly higher levels of vitamin A than those of mothers who had inadequate levels (<33 mcg%).
Local Thermo‐Radiotherapy in Carcinoma Cervix: Improved Local Control versus Increased Incidence of Distant Metastasis
Authors: Sharma Sanjiv , Singhal Sandeep , Sandhu A.P.S. , Ghoshal Sushmita , Gupta B. D. , Yadav N. S. 
Published: August 2010

AbstractIn 1986, 50 patients with stages II and III carcinoma of the cervix were entered into this prospective randomized study. Twenty‐five cases (Group I) were treated only by radical radiation whereas remaining 25 cases (Group II) received local hyperthermia in addition to radical radiation. Hyperthermia was delivered by intracavitary brachyhyperthermia approach using an endotract applicator. Both the groups were followed up for a minimum period of 18 months. Group II patients achieved better local control (14 out of 20 evaluable cases) than the Group I patients (11 out of 22 evaluable cases). A disturbing observation was the increased incidence of distant metastasis in Group II (4 out of 23 cases) as compared to Group I (1 out of 23 cases), though most of them remained disease free locally. The increasing use of hyperthermia in the management of various cancers needs to be reviewed in this context.
Clinicostatistical Study of Ovarian Tumors of Germ Cell Origin
Authors: Shiromizu Kenji , Kawana Takashi , Sugase Motoyasu , Izumi Rikuichi , Mizuno Masahiko 
Published: August 2010

AbstractOvarian tumors of germ cell origin consisted of 440 dermoid cysts, 5 struma ovariis, 3 immature teratomas (G1, G2), 2 carcinoids, 8 dysgerminoma, 3 yolk sac tumors, one choriocarcinoma, 4 dermoid cysts with malignant transformation, and one immature teratoma (G3) of a total of 1,387 ovarian tumors. The patients' mean ages ranged between 17.3 years to 31.9 years, but the mean ages of those with carcinoid and dermoid cyst with malignant transformation were 46.0 and 53.0 years, respectively. In dermoid cyst bilaterality was 17.3% and occurrence during pregnancy or puerperium was 19.6%. In benign tumors, torsion of pedicle and association with pregnancy or puerperium were frequent unlike common epithelial carcinoma, but ascites was rare. Abdominal tumor, pain and metromenorrphagia were the main symptoms, but abdominal distension was scarce with dermoid cysts. The rate of malignant transformation of dermoid cysts was 0.9% overall but 4.3% in patients over 40 years. The prognosis for borderline germ cell tumors was good.
Vitamin A Status of Pregnant Women in Five Districts of Sri Lanka
Authors: Jayasekera J.P.D.J.S. , Atukorala T. M. Sunethra , Seneviratne H. R. 
Published: August 2010

AbstractVitamin A status was assessed in early and late stages of pregnancy in 496 pregnant women living in Colombo, Kurunegala, Kegalle, Badulla and Galle districts, using clinical, dietary and biochemical parameters. Serum vitamin A concentration was determined by a fluorometric method and the retinol binding protein concentration by radial immunodiffusion.The serum vitamin A levels of subjects in the lowest socioeconomic group in Galle and Kegalle districts were significantly lower than those living in Colombo. The percentage of subjects having serum vitamin A levels less than 20 μg/dl, increased in late pregnancy in all areas, with the highest value (27.8%) in the Galle district. None of the subjects had severe ocular manifestations of vitamin A deficiency. The higher incidence of subclinical vitamin A deficiency noted among subjects in Galle and Kegalle districts could be attributed at least in part to a low dietary intake of vitamin A and carotenoids.
Depressed Skull Fracture in a Newborn Successfully Managed Conservatively: A Case Report
Authors: Lim C. T. , Koh M. T. , Sivanesaratnam V. 
Published: August 2010

AbstractA preterm baby was born to a multiparous mother by emergency caesarean section at 36 weeks of gestation. Apart from a depression on the right temporo‐parietal region measuring 3 cm × 3 cm × 0.5 cm, no other abnormality was noted. A CT scan of the brain excluded the presence of intracranial haematoma and pressure effect on the brain. Spontaneous reduction of the fracture without any adverse neurological sequelae suggests that these fractures can be managed conservatively in some instances.
Ovarian Tumors in the Second Decade of Life
Authors: Vani Ramkumar , Kuntal Rao , Rao P.L.N.G. 
Published: August 2010

AbstractA study of 28 adolescents aged 10–20 years admitted with ovarian tumors during a 5‐year period revealed that 75% had malignant ovarian tumors, with germ cell tumors being most frequent. The high incidence of malignancy was due to our hospital being a referral centre. One case of mixed germ cell tumor (mainly choriocarcinoma) presented with precocious puberty, and one case of arrhenoblastoma showed signs of virilization. Tumor markers were found useful in diagnosing choriocarcinoma and endodermal sinus tumor. Amongst the malignant ovarian tumors, the best prognosis was noted with dysgerminomas. Tumors were found more frequently on the right side. Optimal surgery at initial laparotomy, followed by adjuvant chemotherapy or radiotherapy were found to offer the best chance of cure.
Translaparoscopic Tubal Embryo Transfer: Preliminary Experience at National Taiwan University Hospital
Authors: Yang Yu‐Shih , Hwang Jiann‐Loung , Ho Hong‐Nerng , Lien Yih‐Ron , Lin Heng‐Ru , Chiu Yu‐Ho , Lee Tzu‐Yao 
Published: August 2010

AbstractForty‐six couples with various causes of infertility were treated by tubal embryo transfer. Oocyte retrievals were carried out under ultrasound guidance transvaginally and embryos were transferred 48 hours later by laparoscopy into fallopian tubes. Totally 52 cycles were stimulated and 45 retrievals were performed with an average of 8.1 oocytes per retrieval. The average fertilization rate was 54.8%. The implantation rate was 23.8% and the pregnancy rate was 53.5% per transfer. The pregnancy rate per transfer was comparable whether 3 or 4 embryos were transferred. Nine (39.1%) of the 23 pregnancies had multiple pregnancies. Six cases (26.1%) aborted in the first trimester and the remaining 17 were ongoing or term delivery.
Effects of Oxytocin Antagonist (dTVT) and Ritodrine on Spontaneous and Oxytocics‐Induced Uterine Contractions in Pregnant Rats
Authors: Chimura Tetsuro 
Published: August 2010

AbstractThe effect of a recently developed oxytocin antagonist dTVT, i.e. deamino‐[2‐D‐tyrosine(OEt)‐4‐threonine‐8‐ornithine] oxytocin on uterine contraction of pregnant rats was studied in vitro. The following results were obtained.1. dTVT treatment did not affect spontaneous PGE2‐ or PGF2α‐stimulated contraction, while it slightly suppressed PGE1 analogue (Gemeprost)‐stimulated contraction of the uterus.2. Following treatment with dTVT (5–50 μg/ml), oxytocin‐stimulated uterine contraction was gradually and slowly suppressed, resulting in an attenuation curve. Ritodrine treatment, on the other hand, rapidly suppressed spontaneous uterine contraction as well as contraction stimulated by various oxytocics. Suppression of oxytocin‐stimulated uterine contraction by dTVT took much longer (14.8±1.1 min) to take effect than that by ritodrine (<1 min).
Idiopathic Pulmonary Fibrosis (IPF) Necessitating Therapeutic Midtrimester Abortion: A Case Report
Authors: Sholapurkar Shashikant L. , Vasishta Kala , Dhall Gian I. , Jindal Surinder K. 
Published: August 2010

AbstractA 35‐year old multiparous lady was admitted at 19 weeks of pregnancy with rapid onset of dyspnoea which progressed to grade III in 2 months. She was diagnosed as a case of idiopathic pulmonary fibrosis (IPF). She had a vital capacity of 1.25 l, 46.5% of predicted and PaO2 of 60 mmHg at rest, dropping to 35 mmHg on mild exercise testing. She did not respond to prednisolone 40 mg daily given orally for one month. In view of lack of improvement, therapeutic abortion was carried out at 24 weeks by abdominal hysterotomy combined with tubal ligation. Subsequent to termination of pregnancy, her clinical status and pulmonary function improved markedly and she had only grade I dyspnoea 30 months later without corticosteroids. Effect of pregnancy on interstitial lung disorders especially IPF is not yet clear beacuse of extreme rarity of their association. Therapeutic abortion should be seriously considered in patients who cannot increase their oxygen consumption 3 times normal without uncorrectable hypoxaemia.
Obstetric Performance in the Elderly Malaysian Primigravida
Authors: Urquhart D. Rennie , Tai Christina 
Published: August 2010

AbstractThe obstetric performance of 240 elderly primigravida delivering at the University Hospital, Kuala Lumpur, Malaysia between January 1987 and February 1990 was compared with a random group of 250 young primigravida delivering during the same time period. The incidence of impaired glucose tolerance, diabetes mellitus, preterm delivery, antepartum haemorrhage and malpresentation was all increased in the elderly primigravida group. The incidence of caesarean section in the older group was 40.4% compared with 6.8% in the younger (p<0.001). Recent studies suggest that the perinatal mortality in women who delay having their first baby until after the age of 35 is not significantly different from the rest of the obstetric population. However, in our own population of elderly primigravida, although not quite reaching statistical significance the perinatal mortality rate of 46 per 1,000 is three times that of primigravida aged 20–25. This may reflect our low induction rate (7.5%) and assisted vaginal delivery rate (8.3%) in those women in this high risk group who are allowed to labour. The implications of these findings are discussed.
Role of Antenatal Care in Reducing Maternal Mortality
Authors: Pandit Ramesh D. 
Published: August 2010

AbstractMaternal mortality in the developed nations has been considerably reduced, but it still is very high in developing nations. I carried out an indepth study of maternal mortality at N. Wadia Maternity Hospital, Bombay. India, from 1929 to 1988, which revealed that the MMR which was 1920 per 100,000 live births during 1929–1939 period has declined to 82 per 100,000 live births during 1980–1988 period. This achievement in reduction of maternal mortality over the decades was due to multiple factors like increased and effective antenatal, intranatal, and postnatal care. This study shows the apathy of pregnant women to come forward to avail of antenatal care though available even free of charge nearby. To give maximum benefits to pregnant women specially in the developing nations, we have to carry the antenatal care at the doorsteps of the community.
Chorionic Villus Sampling: Evaluation of Obstetric Performance
Authors: Ng Ngee‐Keng , Liu David T. Y. 
Published: August 2010

AbstractChorionic villus sampling is frequently utilised in the Nottingham region as a means of early prenatal diagnosis of genetic problems. Its relative safety in the early antenatal period is well established but there has been some concern that perinatal mortality may be greater in the chorionic villus sampling group as compared to am‐niocentesis. We have in response studied our own data and report the obstetric outcome in 144 cases where the pregnancy has progressed beyond 28 weeks gestation. We have selected a procedure free control group matched for parity.We have found no significant difference in the perinatal outcome and obstetric performance and conclude that at this juncture we should continue to offer our services as chorionic villus sampling offers significant advantages in the first trimester over amniocentesis.
Immunohistochemical Assessment of the Growth Fraction in Cervical Cancers Using the Monoclonal Antibody Ki‐67; Relationship to the Clinical Stage, Histologic Type and DNA Content
Authors: Masuda Tomoyuki , Yabushita Hiromitsu , Sawaguchi Keizo , Noguchi Masayoshi , Nakanishi Masami 
Published: August 2010

AbstractTo assess the growth potential of cervical cancer, cell populations in proliferating cycle (%PC) were examined by an immunohistochemical technique using the monoclonal antibody Ki‐67. The %PC was 31.63+16.61% in 36 cervical cancers and was significantly higher when compared to the 7.8±3.81% found in 24 samples of normal ectocervical tissues. In cervical cancer tissues, the %PC increased in accordance with progression of the clinical stage of the disease, however, the %PC was not different among the various histologic types of invasive cervical cancers. The DNA index also increased in accordance with progression of the clinical stage of cervical cancer, however, there was no correlation between the %PC and the DNA index. These results suggest that the value of %PC obtained using the monoclonal antibody Ki‐67 can be used as a parameter for evaluating the growth activity of cervical cancer and for predicting biological heterogeneity in a tumor.
The Israel Perinatal Census
Authors: Mor‐Yosef Shlomo , Samueloff Arnon , Schenker Joseph G. 
Published: August 2010

AbstractA nation‐wide perinatal census which included 22,815 deliveries was carried out. The cesarean section rate was 9.6% and the perinatal mortality rate was 13.5/1000. Using a logistic regression analysis the risk factors for cesarean section and for perinatal mortality were ranked. Breech presentation and one uterine scar were found to be the most important risk factors for cesarean section and breech presentation, maternal disease and multiple pregnancy for perinatal mortality.Low birth weight rate was 6.9% with nonsignificant differences between the various ethnic groups. The national cesarean section rate in breech presentation was 57.8%. It was performed mainly at the extremes of birth weight.From those with one previous cesarean section 55.1% delivered vaginally and 44.9% abdominally. The chance for vaginal delivery is higher (67.2%) providing the woman had delivered vaginally in the past.Comparison between primiparae and multiparae showed that preeclampsia, hypertension and diabetes mellitus were all significantly more frequent among older parturients and among primiparae.
Elastase Activity of Endocervical Mucus in Normal Pregnancy*
Authors: Limvarapuss Chainarong , Kanayama Naohiro , Terao Toshihiko 
Published: August 2010

AbstractElastase activity of 294 samples of endocervical mucus taken from 125 normal pregnant women during the visits to antenatal clinic were measured. Activity of the enzyme increased gradually with the advance of gestational age. Steep rising of the enzyme was seen between 34–35 weeks of gestation and the peak was achieved at 37 week since then the enzyme activity sustained at relatively high level until deliveries. Average activity of the enzyme after 34 weeks of gestation showed significant difference over that of earlier period. To use delivery date as a referent point, the peak was reached in the last fourth week of pregnancies and then sustained until deliveries. Significantly higher average activity was also seen in these last 4 weeks of gesation. These correlated very well to the fact that cervical maturation progresses most rapidly during last month of pregnancy. Immunohistochemical staining for elastase demonstrated elas‐tase‐containing granules in polymorphonuclear leukocytes. These cells found in cervical tissue taken from immediately postpartal women were much more than in those of early pregnant women. These findings may be the evidences support roles of granulocyte elastase in the process of cervical maturation preceding spontaneous labors in normal pregnancies.
Changes in cAMP‐Dependent Phosphorylation of Specific Cytosol Protein in the Peri‐ and Postmenopausal Ovary
Authors: Ushiroyama Takahisa , Tanigawa Yoshinori , Sugimoto Osamu 
Published: August 2010

AbstractChanges in cAMP‐dependent phosphorylation of 53 kDa protein in a human ovary with respect to the aging process were studied. The phosphorylation of endogenous proteins in ovarian cytosol decreased with aging. However, ovarian aging was accompanied by an increase in the cAMP‐dependent phosphorylation of 53 kDa specific protein while the amount of this protein decreased with aging.The plasma gonadotropin levels of women with regular menstrual periods were significantly different from those of women whose menstrual periods had in the recent past become irregular (FSH: p<0.01; LH: p<0.05); however, there was no significant difference in the plasma estradiol levels between these two groups.Our data show the possible correlations between the non‐steroidal ovarian factor (53 kDa protein) and/or its phosphorylation by cAMP‐dependent protein kinase and the ovarian aging process.
A Case Report: Vesico‐Rectal Fistula with Ano‐Urethral Atresia
Authors: Anandakumar C. , Wong Y. C. , Biswas A. , Venkat A. , Chia D. , Arulkumaran S. , Ratnam S. S. 
Published: August 2010

AbstractVesico‐rectal fistula is a rare congenital abnormality causing severe early second trimester oligohydramnios. Prenatal diagnosis of such a case is reported here. Ultrasound diagnosis could be aided by transabdominal amnio‐infusion and, if necessary, fetal intraperitoneal saline instillation. In a karyotypically normal fetus with normal somatic growth, demonstration of normal fetal kidneys together with a functioning urinary bladder, in presence of severe oligohydramnios, is very suggestive of the diagnosis. Since pulmonary hypoplasia is the major cause of neonatal mortality in these cases, restoration of normal amniotic fluid volume by serial amnio‐infusion was attempted. Although amnio‐infusion is an important diagnostic aid in the evaluation of severe midtrimester oligohydramnios, the role of multiple therapeutic amnio‐infusion in improving lung growth remains to be evaluated.
Acute Abdomen Due to Adenomyosis of the Uterus: A Case Report
Authors: Fujino Toshinori , Watanabe Tomoko , Shinmura Ryoji , Hahn Liangping , Nagata Yukihiro , Hasui Kazuhisa 
Published: August 2010

AbstractA Japanese woman with severe abdominal pain underwent an emergent exploratory laparotomy. Intraperitoneal bleeding from the uterine serosal surface was observed, and a pathologic examination showed that the bleeding was caused by an exudative hemorrhage from the endometrial tissues in the myometrium close to the uterine serosal surface.
Measurement of Serum Rubella Antibody Titers in Korean Children, Female Adolescents, and Pregnant Women
Authors: Lee Im‐Soon , Kim Chang‐Hwi , Lee Sang‐Jhoo , Cho Tai‐Ho 
Published: August 2010

AbstractIgG antibody titers to rubella virus in serum of 322 nuchal cord blood, 1,473 children, and 1,103 reproductive and pregnant women were detected in Soonchunhyang University Hospital in Korea.Positive rate of IgG antibody to rubella virus was 86.3% (278/322) in nuchal cord blood, 68.0% (991/1,458) in children. The IgG antibody from the mother disappeared between the 7th to 11th month after birth, and then the positive rate increased as age increased.In the reproductive age group including pregnant women, positive rate of IgG antibody was 81.8% (894/1,103). Therefore, it was known that there was a possibility that 18.9% of this group would be attacked with rubella in Korea.
The Effects of Glucose Concentration on Early Embryogenesis Using the Whole Embryo Culture System on Rats
Authors: Katase Tsuyoshi , Tetsuo Masahiro , Hamada Teiji , Yakushiji Michiaki 
Published: August 2010

AbstractIn order to investigate the effect of hyperglycemia on fetal teratogenesis, rat embryo culture was performed according to the method of New et al. The effect of hyperglycemia was then studied at glucose concentrations of 300, 600, 900 and 1,200 mg/dl in the medium. The embryos from the high glucose medium (600 mg/dl) had significantly shorter CRLs and fewer somites. Major anomalies characterized by neural lesions and minor anomalies characterized by extraneural lesions increased as the glucose concentration increased. However, fetal growth was promoted with statistical significance in the medium with 300 mg/dl of glucose, where the incidence of malformations remained unchanged as compared to the control group. The findings indicate that the glucose is one of the substantial compounds which influences embryo growth, development and abnormalities, but glucose alone appears to have no major effect on early embryogenesis in diabetic pregnancy.
Thymidylate Synthase Activity in Normal and Malignant Gynecologic Tissues
Authors: Suzuki M. , Ohwada M. , Tamada T. 
Published: August 2010

AbstractWe assayed thymidylate synthase (TS) activity in normal and malignant gynecologic tissues. TS activity in the normal cervix, secretory endometrium, and ovaries from a total of 61 patients was 1.00±0.52pmol/g tissue (mean±SD). Thus the upper limit (mean+2SD) of TS activity in normal gynecologic tissue was 2.00 pmol/g tissue. TS activity was generally higher in malignant tissue than in normal tissue, and particularly high activity was detected in cervical cancer. TS activity in endo‐metrial cancer was relatively low, but activity in poorly and moderately differentiated tumors was significantly elevated compared to well differentiated tumors. These findings suggest that cervical cancer is a highly proliferative tumor and that in endo‐metrial cancer, cell proliferation is more rapid in poorly differentiated tumors than in well differentiated ones.
Combined Examination of Middle Cerebral Artery and Umbilical Artery Flow Velocity Waveforms in Growth‐Retarded Fetuses
Authors: Sekizuka Naoto 
Published: August 2010

AbstractThe resistance index (RI) of middle cerebral artery (MCA) and umbilical artery (UA) flow velocity waveforms (FVWs) were characterized retrospectively in 60 growth‐retarded fetuses in the third trimester of gestation. Reference ranges of MCA‐RI, UA‐RI, and the UA‐RI/MCA‐RI ratio to gestational age were obtained from a cross‐sectional study of 150 healthy fetuses. Growth‐retarded fetuses that developed fetal distress had lower MCA‐RIs, higher UA‐RIs, and higher UA‐RI/MCA‐RI ratios than growth‐retarded fetuses that had good outcomes. The highest sensitivity for fetal distress was observed in the UA‐RI/MCA‐RI ratio (UA‐RI/MCA‐RI 94.1%, MCA‐RI 79.4%, UA‐RI 61.8%), and the highest specificity was in MCA‐RI (MCA‐RI 92.3%, UA‐RI 84.6%, UA‐RI/MCA‐RI 76.9%). In growth‐retarded fetuses, the combined examination of MCA FVWs and UA FVWs was more useful in assessing fetal well‐being than examination of UA FVWs alone.