bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rhabdomyolysis and acute renal failure following minimally invasive spine surgery
Authors: Dakwar Elias , Rifkin Stephen I. , Volcan Ildemaro J. , Goodrich J. Allan , Uribe Juan S. 
Published: March 2011

Minimally invasive spine surgery is increasingly used to treat various spinal pathologies with the goal of minimizing destruction of the surrounding tissues. Rhabdomyolysis (RM) is a rare but known complication of spine surgery, and acute renal failure (ARF) is in turn a potential complication of severe RM. The authors report the first known case series of RM and ARF following minimally invasive lateral spine surgery.
The authors retrospectively reviewed data in all consecutive patients who underwent a minimally invasive lateral transpsoas approach for interbody fusion with the subsequent development of RM and ARF at 2 institutions between 2006 and 2009. Demographic variables, patient home medications, preoperative laboratory values, and anesthetic used during the procedure were reviewed. All patient data were recorded including the operative procedure, patient positioning, postoperative hospital course, operative time, blood loss, creatine phosphokinase (CPK), creatinine, duration of hospital stay, and complications.
Five of 315 consecutive patients were identified with RM and ARF after undergoing minimally invasive lateral transpsoas spine surgery. There were 4 men and 1 woman with a mean age of 66 years (range 60–71 years). The mean body mass index was 31 kg/m2 and ranged from 25 to 40 kg/m2. Nineteen interbody levels had been fused, with a range of 3–6 levels per patient. The mean operative time was 420 minutes and ranged from 315 to 600 minutes. The CPK ranged from 5000 to 56,000 U/L, with a mean of 25,861 U/L. Two of the 5 patients required temporary hemodialysis, while 3 required only aggressive fluid resuscitation. The mean duration of the hospital stay was 12 days, with a range of 3–25 days
Rhabdomyolysis is a rare but known potential complication of spine surgery. The authors describe the first case series associated with the minimally invasive lateral approach. Surgeons must be aware of the possibility of postoperative RM and ARF, particularly in morbidly obese patients and in procedures associated with prolonged operative times.
Texte de la Déclaration de Vienne (18 Juillet 2010)
Authors: Wood Evan 
Published: March 2011

Résumé Rédigée par une équipe de chercheurs internationaux dirigée par le Canadien Evan Wood, cette déclaration met en avant le fait que la criminalisation des utilisateurs de drogues illicites alimente l’épidémie de VIH et qu’elle a eu des retombées négatives sur la santé et la société. Cette déclaration met gouvernements et Nations Unies au défi de réorienter complètement leurs politiques en matière de drogues.
Histoire de la constitution d'une norme anti-drogue internationale
Authors: Maguet Olivier , Dumand Dominique 
Published: March 2011

Résumé Depuis le début du siècle, les États ont élaboré un corpus de recommandations constituant une véritable norme en matière de drogues. Ils les ont inscrites dans leur législation nationale et en délèguent au système onusien le contrôle de l’application au niveau mondial. Les conséquences de l’application de cette norme anti-drogue, qui s’appuie sur un mélange de morale (le « fléau » des drogues), d’hygiénisme (les effets délétères des usages abusifs de drogues) et d’intérêts économiques (les profits de l’industrie pharmaceutique) en France et à l’étranger, sont désastreuses sur les populations.
Lentiviral Vector Mediated Transgenesis
Authors: Barde Isabelle , Verp Sonia , Offner Sandra , Trono Didier 
Published: March 2011

AbstractThe genetic manipulation of rodents through the generation of fully transgenic animals or via the modification of selective cells or organs is a procedure of paramount importance for biomedical research, either to address fundamental questions or to develop preclinical models of human diseases. Lentiviral vectors occupy the front stage in this scene, as they can mediate the integration and stable expression of transgenes both in vitro and in vivo. Widely used to modify a variety of cells, including re‐implantable somatic and embryonic stem cells, lentiviral vectors can also be directly administered in vivo, for instance in the brain. However, perhaps their most spectacular research application is in the generation of transgenic animals. Compared with the three‐decade‐old DNA pronuclear injection technique, lentivector‐mediated transgenesis is simple, cheap, and highly efficient. Furthermore, it can take full advantage of the great diversity of lentiviral vectors developed for other applications, and thus allows for ubiquitous or tissue‐specific or constitutive or externally controllable transgene expression, as well as RNAi‐mediated gene knockdown. Curr. Protoc. Mouse Biol. 1:169‐184. © 2011 by John Wiley & Sons, Inc.
Formation of Ultrafine‐Grained Microstructure of Ti–6Al–4V Alloy by Hot Deformation of α′ Martensite Starting Microstructure
Authors: Matsumoto Hiroaki , Lee Sang‐Hak , Ono Yoshiki , Li Yunping , Chiba Akihiko 
Published: March 2011

AbstractWe have presented a formation of ultrafine‐grained microstructure (dα ≈ 0.2 µm) of industrial Ti–6Al–4V alloy produced by the hot compression of a sample with the acicular α′ martensite starting microstructure. The hot‐deformation behavior was different from the case of the conventional (α + β) starting microstructure, that is, the phase transformation of α′/(α + β) during hot working enhanced the microstructural conversion, especially under the conditions of a low temperature and a high‐strain rate.
Prospective evaluation of preoperative concern among patients considering endoscopic sinus surgery: initial validation
Authors: Brandt Michael G. , Rotenberg Brian W. , Yeung Jeff C. , Franklin Jason H. , Doyle Philip C. 
Published: March 2011

AbstractBackgroundPatients considering surgery face many uncertainties and concerns. This investigation aimed to develop an objective assessment tool for characterizing the areas of greatest concern among patients considering endoscopic sinus surgery (ESS).MethodsAs part of validating a clinical measure concerning perioperative concerns, patients presenting with chronic rhinosinusitis with or without nasal polyposis were voluntarily recruited. A total of 30 individuals completed a novel 19‐item questionnaire during their initial clinical visit and again 3 days later. Outcomes included descriptive statistics and test‐retest reliability.ResultsData suggest that patient responses did not vary with age or gender. The questionnaire demonstrated strong test‐retest reliability, with alpha values from 0.881 to 0.942. Between‐rater reliability was consistent, with an average intraclass correlation coefficient (ICC) of 0.913. No relationships between question order and patient response was identified.ConclusionPatients considering ESS have concerns that remain stable in the early preoperative period requiring surgeon‐initiated inquiry and counsel. This is the first study to evaluate preoperative patient concerns, and initially establishes the Western Surgical Concern Inventory‐ESS (WSCI‐ESS) as a means of ensuring adequate patient counseling and a method of evaluating perioperative patient education. © 2011 ARS‐AAOA, LLC.
A randomized trial examining the effect of pretreatment point‐of‐care computed tomography imaging on the management of patients with chronic rhinosinusitis symptoms
Authors: Tan Bruce K. , Chandra Rakesh K. , Conley David B. , Tudor Robin Smolak , Kern Robert C. 
Published: March 2011

AbstractBackgroundRecent consensus statements on the diagnosis of chronic rhinosinusitis (CRS) now require endoscopic or radiographic evidence of paranasal sinus inflammation. The timing of point‐of‐care (POC) computed tomography (CT) scan in the workup of these patients remains to be elucidated, particularly when endoscopy is negative. The objective of this research was to prospectively evaluate 2 algorithms for the initial management of patients with symptoms of CRS who manifest a normal nasal endoscopic examination.MethodsA total of 40 such patients were randomized to 1 of 2 pathways: POC‐CT at the initial visit followed by medical therapy based upon CT results (pre‐CT group; n = 20), or empiric medical therapy (EMT) followed by POC posttreatment CT if symptoms persisted (EMT group; n = 20).ResultsThe 2 groups were demographically and symptomatically similar with regard to 2003 Task Force major criteria. Otolaryngology follow‐up was recommended in 11 of 20 pre‐CT patients, all of whom (100%) returned. In contrast, only 10 of 20 EMT patients (50%) followed up as instructed (p < 0.05). Radiographic confirmation of CRS was found in 8 of 20 pre‐CT patients, and only 2 of 9 patients after EMT (p = 0.61). EMT patients received more antibiotic prescriptions (relative ratio [RR], 2.50; 95% CI, 1.46–4.27), while pre‐CT patients received more CT scans (RR, 2.22; 95% CI, 1.37–3.61). Overall prescriptions costs were similar to the EMT group ($253 vs $218; p = 0.37) and the overall number of otolaryngology visits was similar.ConclusionIn patients with symptoms of CRS but negative endoscopy, POC at initial presentation results in substantially less unnecessary antibiotic prescriptions and significantly greater compliance with otolaryngology care but does result in a higher utilization of radiographic imaging. © 2011 ARS‐AAOA, LLC.
Antibacterial activity and antistatic composites of polyester/Ag‐SiO2 prepared by a sol–gel method
Authors: Wu Chin‐San , Liao Hsin‐Tzu 
Published: March 2011

AbstractPoly(butylene adipate‐co‐terephthalate) (PBAT) composites containing silver‐silica (Ag‐SiO2) were prepared using an in‐situ sol–gel process. Maleic anhydride‐grafted PBAT (PBAT‐g‐MA) and multihydroxyl‐functionalized Ag‐SiO2 were used to improve the compatibility and dispersibility of Ag‐SiO2 within the PBAT matrix. The composites were characterized morphologically using transmission electron microscopy and chemically using Fourier transform infrared spectrometry. The existence of Ag‐SiO2 nanoparticles on the substrate was confirmed by the ultraviolet–visible absorption spectra. The antibacterial and antistatic properties of the composites were evaluated whether SiO2 enhanced the electrical conductivity was tested as well as whether Ag enhanced the antibacterial activity of the PBAT‐g‐MA/SiO2 or PBAT/SiO2 composites. The PBAT‐g‐MA/SiO2 or PBAT/SiO2 composite that contained Ag had better antibacterial activity (more than 1.3‐fold). The functionalized PBAT‐g‐MA/Ag‐SiO2 composite can markedly enhanced antibacterial and antistatic properties due to the carboxyl groups of maleic anhydride, which acted as coordination sites for the Ag‐SiO2 phase, allowing the formation of stronger chemical bonds. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Probing molecular mobility during crosslinking process of commercial resins by NMR multiexponential relaxation data analysis
Authors: de L. Campello Sérgio , de Souza Ricardo E. , de Azevedo Walter M. 
Published: March 2011

AbstractIn this study, we present the experimental results for the crosslinking process of a commercial polyester resin based on measurements of the spin lattice relaxation time T1 of protons, as function of the crosslinking time evolution. Multiexponential decomposition of the evolution of magnetization measured in inversion‐recovery experiments is performed. The population of “rigid” and “mobile” nuclear spin sites was estimated as function of time evolution. In analogy to the usual monomer conversion u, site conversion from “mobile” to “rigid” sites uM were also estimated as a function of time evolution and initial concentrations of the reagents. The multiexponential decomposition approach of T1 relaxation data allows one to follow crosslinking processes. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Biodegradability studies on natural fibers reinforced polypropylene composites
Authors: Chattopadhyay Sanjay K. , Singh Sanjay , Pramanik Nilay , Niyogi U. K. , Khandal R. K. , Uppaluri Ramagopal , Ghoshal Aloke K. 
Published: March 2011

AbstractVarious composites of polypropylene (PP) produced using natural fibers such as pineapple leaf fiber, banana fiber, and bamboo fiber were studied for their degree and rate of aerobic biodegradation. Composites used contained 10, 15, and 50% volume fractions of pineapple leaf fiber, banana fiber, and bamboo fiber, respectively, which are the optimum fiber percentages of the respective composites as reported by these authors in their previous works. Cellulose has been used as positive reference material. All the composites exhibited partial biodegradation in the range of 5–15% depending on the fiber content. Degradation had not taken place in the covalent ester linkages between the natural fiber and the MA‐g‐PP compatibilizer but in those areas of the fibers which have remained only physically embedded in the resin matrix. Thus, although natural fibers reinforced PP composites are not excellent biodegradable material, they can address to the management of waste plastics by reducing the amount of polymer content used that in turn will reduce the generation of nonbiodegradable polymeric wastes. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Evaluation of chitosan and their self‐assembled nanoparticles with pDNA for the application in gene therapy
Authors: Sarkar Kishor , Srivastava Rishi , Chatterji Urmi , Kundu P. P. 
Published: March 2011

AbstractThe molecular weight (MW) of chitosan (CS) was determined by viscometric method (using Mark‐Houwink equation) as well as by gel permeation chromatography, and the degree of deacetylation (DDA) of CS was measured by potentiometric titration method and Gran‐type linearization method. The values of DDA were obtained ∼ 83% (by potentiometric titration method) and ∼ 86% (by Gran‐type linearization method). The self‐assembled nanoparticles of CS/plasmid DNA (pDNA) complex were prepared by varying the concentration of CS. The formation of CS/pDNA complex was confirmed by 0.8% agarose gel electrophoresis and the particle size of the self‐assembled nanoparticle was determined by dynamic light scattering, atomic force microscopy and scanning electron microscopy. The stability of CS/pDNA complexes was determined by turbidity test with the help of UV‐Vis spectroscopy. The effect of ionic strength on the complexes was also observed by means of fluorescence spectroscopy. The cytotoxicity of CS on the HeLa cell line was observed by absorbance of MTT (3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide) assay and showed that CS has lower cytotoxicity in HeLa cells compared with that of poly (L‐lysine) in 293T cells. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Electrical and thermal conductivity and tensile and flexural properties: Comparison of carbon black/polycarbonate and carbon nanotube/polycarbonate resins
Authors: King Julia A. , Via Michael D. , King Michelle E. , Miskioglu Ibrahim , Bogucki Gregg R. 
Published: March 2011

AbstractAdding conductive carbon fillers to thermoplastic polymers increases the resulting composite's electrical conductivity. Carbon black (CB) is very effective at increasing composite electrical conductivity at low loading levels. In this study, varying amounts (2 to 10 wt %) CB were added to polycarbonate (PC) and the resulting composites were tested for electrical conductivity (1/electrical resistivity), thermal conductivity, and tensile and flexural properties. These results were compared with prior work done for carbon nanotubes (CNT) in polycarbonate. The percolation threshold was ∼ 2.3 vol % CB compared to between 0.7 and 1.4 vol % CNT. At 8 wt % filler, the CNT/PC composite had an electrical resistivity of 8 ohm‐cm compared to 122 ohm‐cm for the CB/PC composite. The addition of CB to polycarbonate increased the composite electrical and thermal conductivity and tensile and flexural modulus. The 8 wt % (5.5 vol %) CB in polycarbonate composite had a good combination of properties for semiconductive applications. Ductile tensile behavior is noted in pure polycarbonate and in samples containing up to 8 wt % CB. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Study of optical losses in poly(3‐octylthiophene) planar and inverted RIB waveguides
Authors: Messaad Khalida , Charrier Joël , Mosqueron Alexandra , Bosc Dominique , Rochard Philippe 
Published: March 2011

AbstractPoly(3‐octylthiophene), (P3OT) in addition to its electronics properties exhibits a high Kerr coefficient, n2, due to its third order nonlinear dielectric susceptibility. At the wavelength of 1550 nm, this coefficient n2 is one of the highest. So, this material should be suitable to build integrated all optical switching devices. To construct this device, it is necessary to make a single‐mode optical waveguide. For the time being, such a P3OT waveguide has never been obtained due to excessive optical losses. In view to produce single‐mode waveguide with P3OT as a core, we investigated the different causes of these optical losses in the material and in the guiding structure. We characterized the optical transmission at key steps in its development. First, we demonstrated that the intrinsic polymer absorption is not a limiting factor at 1550 nm, and then we studied the transmission properties of planar (1‐D confined light) and channel waveguides (2‐D confined light). The results revealed that better transmission properties can be achieved using planar waveguides rather that confined channel waveguides. This article describes the development and the characterization of the guiding structures that enabled us to identify the main origins of optical losses. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Rationale and design of the randomized, multicenter EREMUS trial, a study that investigates how to achieve low restenosis and early reendothelialization after percutaneous coronary interventions
Authors: Cortese Bernardo , Danzi Gian Battista , Pitì Antonino , Severi Silva , Limbruno Ugo 
Published: March 2011

AbstractBackground: Drug eluting stent (DES) use has improved clinical outcome after percutaneous coronary interventions. However, DES‐treated patients may have a higher risk of stent thrombosis, mainly due to uncorrect stent deployment or lack of reendothelialization. Thus, the availabilily of different approaches with comparable efficacy to DES, but higher safety, especially in bleeding‐prone patients, have to be investigated. Study Design: The EREMUS is a multicenter open‐label prospective randomized three‐arm clinical trial that will investigate the efficacy of a paclitaxel coated balloon + an endothelial progenitor capture stent for the treatment of native coronary lesions, and compare it to a DES strategy, or the sole endothelial progenitor capture stent. An angiographic follow‐up with optical coherence tomography analysis will be scheduled 9 months after index procedure. Noninferiority regarding the primary endpoint (late luminal loss) between study group and DES is hypothesized. All patients will undergo clinical follow‐up until 24 months from index hospitalization. Conclusions: The EREMUS trial will determine whether a composite approach with a paclitaxel coated balloon + an endothelial progenitor capture stent in coronary lesions at medium‐to‐high risk of restenosis will achieve similar results compared to DES regarding inhibition of intrastent proliferation; complete stent strut reendothelialization, a safety issue, will also be investigated. © 2011 Wiley‐Liss, Inc.
Aortic valve perforation during aortic valvuloplasty
Authors: Ussia Gian Paolo , Sarkar Kunal , Tamburino Corrado 
Published: March 2011

AbstractBalloon aortic valvuloplasty has seen a revival in interest because of its role in predilation and preparation of the annulus before trans catheter aortic valve implantation. Aortic valve cusp perforation is a serious complication that needs early recognition and prompt corrective measures to prevent a poor procedural outcome or conversion to emergent surgery. A number of useful angiographic and technical findings can alert the operator about the possibility of this complication. Failure to recognize cusp perforation can lead to serious procedural complications like severe aortic regurgitation, suboptimal prosthesis deployment, and function that can necessitate emergent open cardiac surgery © 2011 Wiley‐Liss, Inc.
Supported percutaneous coronary intervention using a novel 6‐Fr intra‐aortic balloon pump catheter via the brachial artery in a nonagenarian patient with an abdominal aortic aneurysm
Authors: Takahashi Akihiko , Taniguchi Norimasa 
Published: March 2011

AbstractIntra‐aortic balloon pump (IABP) counterpulsation is a useful hemodynamic assist device during complex percutaneous coronary intervention (PCI) in patients with poor left ventricular function; however, the presence of an abdominal aortic aneurysm poses a problem, because insertion via the femoral artery may cause distal embolism and aneurysm rupture. A 92‐year‐old man with unstable angina was admitted to our hospital. Coronary angiography revealed chronic total occlusion of the proximal left anterior descending artery and severe stenosis of the left circumflex artery (LCX). The left ventricular ejection fraction was 36%. He also had an infrarenal abdominal aortic aneurysm with a diameter of 55 mm. Supported PCI was performed for the management of the LCX lesion. A novel 6‐Fr IABP catheter was inserted via the left brachial artery. The lesion was successfully dilated, and a 3.0 × 13 mm Cypher® stent was placed. After the PCI procedure, the IABP catheter was retrieved in the catheter laboratory, and the patient was discharged after 7 days. When a femoral approach is contraindicated in PCI, 6‐Fr IABP catheter insertion via the brachial artery is feasible and effective. © 2011 Wiley‐Liss, Inc.
Percutaneous coronary intervention of left main pseudoaneurysm with customized covered stents
Authors: Dhakam Sajid , Ahmeed Hafeez , Jafarani Asif 
Published: March 2011

AbstractLeft main pseuodaneurysm is a rare entity and is one of the potentially lethal consequences of coronary artery dissection. We describe a case of a young woman who almost a week after her delivery developed spontaneous left main dissection, manifested as acute anterior myocardial infarction. Left on medical treatment alone over a month, spontaneous dissection progressed to symptomatic large left main pseuodaneurysm, which was treated percutaneously with covered stents. © 2011 Wiley‐Liss, Inc.
Transhepatic portal vein access for balloon dilation of right upper pulmonary vein stenosis following infradiaphragmatic total anomalous pulmonary venous drainage repair
Authors: Tzifa Aphrodite , Ahmed Irfan , Rosenthal Eric 
Published: March 2011

AbstractTranshepatic cardiac catheterization is now a well‐established alternative when conventional venous routes for cardiac access have failed. Some operators prefer this route even routinely, due to the direct access that it offers to the right atrium and atrial septum. We report the case of a newborn baby previously operated on for infradiaphragmatic total anomalous pulmonary venous drainage who represented with right sided pulmonary vein stenosis. Transhepatic portal vein access, first reported here, gave direct access to the right upper pulmonary vein, through the patent descending vein, after the conventional transfemoral venous and retrograde arterial routes had failed. © 2011 Wiley‐Liss, Inc.