bluuebunny/crossref_metadata_2025_split huggingface dataset:
Productivity and efficiency dynamics in Indian banking: An input distance function approach incorporating quality of inputs and outputs
Authors: Das Abhiman , Kumbhakar Subal C. 
Published: May 2010

SUMMARYBanking technology is typically characterized by multiple inputs and multiple outputs that are associated with various attributes, such as different types of deposits, loans, number of accounts, classes of employees and location of branches. These quality differentials in inputs and outputs are mostly ignored in empirical studies. These omissions make the practical value of productivity studies in organizations like banks questionable because quality is a key component of performance. This paper proposes using hedonic aggregator functions (as a tool of aggregating inputs and outputs with quality attributes) within an input distance function framework and analyzes the impact of banking deregulation on efficiency and total factor productivity (TFP) change in the Indian banking industry using panel data for the period 1996–2005. Empirical results indicate that banks have improved their efficiency (from 61% in 1996 to 72% in 2005) during the post‐deregulation period, and the gain in efficiency of state‐owned banks has surpassed that of private banks. Improvement in capital base, as indicated by increased capital adequacy ratio, played an important role in ushering efficiency gain. The return to scale estimate suggests that state‐owned banks are operating far above their efficient scale and cost savings can be obtained by reducing their size of operations. Overall, TFP growth was above 3.5% annually. Both technical progress and technical efficiency change consistently played an important role in shaping TFP growth. Copyright © 2010 John Wiley & Sons, Ltd.
Jackknife instrumental variables estimation: replication and extension of angrist, imbens and krueger (1999)
Authors: Nakov Anton 
Published: May 2010

AbstractI replicate most of the results in Angrist, Imbens, and Krueger (Journal of Applied Econometrics 1999; 14: 57–67), point to a possible error in and re‐estimate Model 3, and analyze some simple extensions. The programming code, data, and results are available at http://sites.google.com/site/antonnakov/software. Copyright © 2010 John Wiley & Sons, Ltd.
Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging
Authors: Neugebauer Ute , Clement Joachim H. , Bocklitz Thomas , Krafft Christoph , Popp Jürgen 
Published: May 2010

AbstractMedical diagnosis can be improved significantly by fast, highly sensitive and quantitative cell identification from easily accessible body fluids. Prominent examples are disseminated tumor cells circulating in the peripheral blood of cancer patients. These cells are extremely rare and therefore difficult to detect. In this contribution we present the Raman spectroscopic characterization of different cells that can be found in peripheral blood such as leukocytes, leukemic cells and solid tumor cells. Leukocytes were isolated from the peripheral blood from healthy donors. Breast carcinoma derived tumor cells (MCF‐7, BT‐20) and myeloid leukaemia cells (OCI‐AML3) were prepared from cell cultures. Raman images were collected from dried cells on calcium fluoride slides using 785 nm laser excitation. Unsupervised statistical methods (hierarchical cluster analysis and principal component analysis) were used to visualize spectral differences and cluster formation according to the cell type. With the help of supervised statistical methods (support vector machines) a classification model with 99.7% accuracy rates for the differentiation of the cells was built. The model was successfully applied to identify single cells from an independent mixture of cells based on their vibrational spectra. The classification was confirmed by fluorescence staining of the cells after the Raman measurement. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Density functional theory study of the oxidation of methanol to formaldehyde on a hydrated vanadia cluster
Authors: González‐Navarrete P. , Gracia L. , Calatayud M. , AndréS J. 
Published: May 2010

AbstractDensity functional theory was used to study the mechanism for the oxidation of methanol to formaldehyde. A vanadium oxide cluster OV(OH)3 has been utilized to represent the catalytic system under hydrated conditions, i.e., in the presence of VOH hydroxyl groups. Two types of methoxy‐intermediates have been considered: a penta‐coordinate methoxy‐intermediate (OH)4V(OCH3) and a tetrahedral methoxy‐intermediate (OH)2VO(OCH3)(H2O). The most plausible reaction pathway corresponds to the process involving first the formation of the tetrahedral methoxide, and a subsequent rate‐limiting step where hydrogen is transferred from the methoxy groups toward the oxygen atom of the vanadyl VO site. The reaction mechanism is a typical two‐state reactivity process due to a change of the multiplicity (reactive singlet → product triplet) along the reaction coordinate accompanied by a reduction of the vanadium center from VV (d0) to VIII (d2). Minimum energy crossing points were localized and possible spin inversion processes are discussed by means of the intrinsic reaction coordinate approach to find the most favorable reaction pathways. The hydration effect is found to be mainly the destabilization of the methoxy intermediates. An alternative reaction pathway with a lower apparent barrier is presented. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2010
Bis‐8‐hydroxyquinoline and bis‐8‐hydroxyquinaldine N‐substituted amines: A single methyl group structural difference between the two heterocycles, which modulates the antiproliferative effects
Authors: Madonna Sébastien , Marcowycz Aline , Lamoral‐Theys Delphine , Van Goietsenoven Gwendoline , Dessolin Jean , Pirker Christine , Spiegl‐Kreinecker Sabine , Biraboneye César‐Alain , Berger Walter , Kiss Robert , Kraus Jean‐Louis 
Published: May 2010

Abstract
magnified imageThe synthesis of a series of bis‐8‐hydroxyquinoline‐ and bis‐8‐hydroxyquinaldine‐substituted N‐benzyl or thiophenyl amines and their corresponding bis‐8‐hydroxyquinoline is reported. In vitro growth inhibitory effects of both series have been evaluated. It has been observed that analogs from the bis‐8‐hydroxyquinoline series exert nanomolar range activity, whereas the antiproliferative activity of the corresponding analogs from the bis‐8‐hydroxyquinaldine series was found to be drastically lower. Molecular docking and chemical–physical properties account for these observed growth inhibitory differences between the two series of analogs, which differ only by the presence of a methyl group at the 2 position of the heterocyclic ring. J. Heterocyclic Chem., (2010).
The first in situ Raman spectroscopic study of San rock art in South Africa: procedures and preliminary results
Authors: Tournié Aurélie , Prinsloo Linda C. , Paris Céline , Colomban Philippe , Smith Benjamin 
Published: May 2010

AbstractSouthern Africa has a rich heritage of hunter‐gatherer, herder and farmer rock art traditions made by using both painted and engraved techniques. Until now, there have been only a handful of studies on the chemical analysis of the paint, as all previous types of analysis required the removal of pigment samples from the sites a practice which has been avoided. Raman spectroscopy is an ideal techniques to analyse the paint non‐destructively and also offers the possibility of in situ work with portable instruments. This article describes the procedures and reports the preliminary results of the first in situ Raman spectroscopic study of rock art in South Africa (also a first worldwide), where we, first, evaluate the capability of a Raman portable instrument in very difficult conditions, second, analyse the paints in order to contribute to a better knowledge of the technology used and, third, evaluate the possible contribution of in situ analyses in conservation studies. The paintings from two different rock art sites were studied. The instrument proved to be highly suitable for in situ analyses in physically very challenging conditions. Most of the pigments and alteration products previously detected under laboratory conditions were identified, thereby giving information on both the pigments and conservation state of the paintings. A layered structure of alteration products and pigment was identified in situ for the first time by controlling the laser power, thereby obtaining the same results as in mapping experiments of cross sections of paint. Copyright © 2010 John Wiley & Sons, Ltd.
Claims data linked to hospital registry data enhance evaluation of the quality of care of breast cancer
Authors: Meguerditchian Ari‐Nareg , Stewart Andrew , Roistacher James , Watroba Nancy , Cropp Michael , Edge Stephen B. 
Published: May 2010

AbstractBackgroundComplete treatment data is central to evaluation and improvement of cancer care quality. Cancer registries vary in completeness of radiation (RT), chemotherapy (CT), and hormone therapy (HT) data. Administrative claims from health payers may supplement these registries. This study assesses the ability to link private payer claims to the National Cancer Data Base (NCDB) and the extent of additional treatment data identified in claims.MethodsClaims for patients with breast cancer surgery from one payer in Western New York (WNY) were matched with NCDB for participating hospitals for 2001–2003 using available identifiers (reporting hospital, gender, birth date, ZIP code). Claims were analyzed for breast and axillary surgery, RT, CT, and HT, and compared with treatment recorded in the NCDB.ResultsFour hundred seventy women had claims for breast cancer surgery and 439 (91%) matched to the NCDB. Seventeen had duplicate/incomplete records. Non‐matches included cases with surgery for cancer recurrence. Among 422 evaluable cases, stage was 0: 9%; I: 49%; II: 33%; III: 7%; and IV: 2%. Claims and registry were highly concordant for surgery. Registry identified RT, CT, and HT in 38%, 47%, 18%, respectively, of treatment reported in claims. Claims also provided information on drugs used and treatment duration.ConclusionsThe NCDB can be matched with private payer claims using available identifiers. Registry data in this convenience sample of hospitals did not include a substantial fraction of outpatient data identified by claims. Private payer claims may help enhance the completeness of NCDB treatment information. J. Surg. Oncol. 2010; 101:593–599. © 2010 Wiley‐Liss, Inc.
Characteristics and prognosis of primary thyroid non‐Hodgkin's lymphoma in Chinese patients
Authors: Sun Tuan‐Qi , Zhu Xiao‐Li , Wang Zhuo‐Ying , Wang Chao‐Fu , Zhou Xiao‐Yan , Ji Qing‐Hai , Wu Yi 
Published: May 2010

AbstractBackground and ObjectivesThere exists no universally accepted treatment for primary thyroid non‐Hodgkin's lymphoma (TNHL) due to the rarity of this entity. The aim of this study is to assess the role of surgery and to explore prognostic factors in Chinese TNHL patients.MethodsPatient presentations, pathologies, surgical interventions, multidisciplinary treatment, prognostic factors and the value of fine needle aspiration were analyzed.ResultsBetween 1991 and 2007, 40 patients of TNHL were diagnosed. Thirty‐eight patients underwent an initial surgical procedure. Further treatments consisted of radiotherapy or chemotherapy alone, and the majority of patients were treated with combined chemo‐radiation. After a median follow‐up of 95 months, the 5‐year overall survival (OS) and relapse‐free survival (RFS) was 82% and 74%, respectively. Survival curves showed no significant difference between therapeutic operations when compared with diagnostic operations. A univariate analysis showed both International Prognostic Index (IPI) and staging significantly influenced OS and RFS. In multivariate analysis, IPI was found to be the only prognostic factor.ConclusionsCombined chemotherapy and radiotherapy may offer better outcome without the need for extensive resection, and surgery should be reserved to providing tissue for diagnosis. The patients with low‐intermediate risk (IPI = 2) or stage IIE need be treated more aggressively. J. Surg. Oncol. 2010; 101:545–550. © 2010 Wiley‐Liss, Inc.
High performance liquid chromatography method for the detection of released purinergic and biogenic amine signaling molecules from in vitro ileum tissue
Authors: Lwin Ayemon , Patel Bhavik Anil 
Published: May 2010

AbstractAdenosine triphosphate (ATP) and serotonin (5‐HT) are known to play key roles in the function and activity of the gastrointestinal tract; however, no methods have been established for the monitoring of these signaling molecules within one assay. We have developed a simple chromatographic methodology using UV/visible detection for the analysis of purinergic and biogenic amine signaling molecules. The chromatographic separation was achieved in an isocratic mode, where the mobile phase consisted of 5% methanol and 95% ammonium phosphate buffer with 10 mM tetrabutylammonium bisulfate. Column temperature of 45°C provided the means to separate all analytes within 14.7 min. Good resolution and tailing factors were observed for all components within the separation. The LOD for ATP and 5‐HT was 30 and 317 nM, respectively, with a linear range from 10–0.02 μM. In vitro measurements were carried out by using aliquots from the buffer the tissue was stored in after 30 min to measure released molecules. In vitro assay of ileum tissue in the presence and absence of endogenous ATP was carried out. Results showed that ATP can elevate 5‐HT release. This method can be used to study alterations in these key signaling molecules with gastrointestinal disease.
Coupling stir bar sorptive extraction‐dispersive liquid–liquid microextraction for preconcentration of triazole pesticides from aqueous samples followed by GC‐FID and GC‐MS determinations
Authors: Farajzadeh Mir Ali , Djozan Djavanshir , Nouri Nina , Bamorowat Mehdi , Shalamzari Mohammad Safi 
Published: May 2010

AbstractStir bar sorptive extraction (SBSE) combined with dispersive liquid–liquid microextraction (DLLME) has been developed as a new approach for the extraction of six triazole pesticides (penconazole, hexaconazole, diniconazole, tebuconazole, triticonazole and difenconazole) in aqueous samples prior to GC‐flame ionization detection (GC‐FID). A series of parameters that affect the performance of both steps were thoroughly investigated. Under optimized conditions, aqueous sample was stirred using a stir bar coated with octadecylsilane (ODS) and then target compounds on the sorbent (stir bar) were desorbed with methanol. The extract was mixed with 25 μL of 1,1,2,2‐tetrachloroethane and the mixture was rapidly injected into sodium chloride solution 30% w/v. After centrifugation, an aliquot of the settled organic phase was analyzed by GC‐FID. The methodology showed broad linear ranges for the six triazole pesticides studied, with correlation coefficients higher than 0.993, lower LODs and LOQs between 0.53–24.0 and 1.08–80.0 ng/mL, respectively, and suitable precision (RSD < 5.2%). Moreover, the developed methodology was applied for the determination of target analytes in several samples, including tap, river and well waters, wastewater (before and after purification), and grape and apple juices. Also, the presented SBSE‐DLLME procedure followed by GC‐MS determination was performed on purified wastewater. Penconazole, hexaconazole and diniconazole were detected in the purified wastewater that confirmed the obtained results by GC‐FID determination. In short, by coupling SBSE with DLLME, advantages of two methods are combined to enhance the selectivity and sensitivity of the method. This method showed higher enrichment factors (282–1792) when compared with conventional methods of sample preparation to screen pesticides in aqueous samples.
New outbred colony derived from Mus musculus castaneus to identify skin tumor susceptibility loci
Authors: Fujiwara Kyoko , Wie Benjamin , Elliott Rosemary , Nagase Hiroki 
Published: May 2010

AbstractSusceptibility to tumor development varies among mice strains. Using inbred NIH and wild‐derived outbred Mus spretus backcrosses, skin cancer‐susceptibility loci were mapped [Nagase et al. 1995. Nat Genet 10: 424–429; Nagase et al. 1999. Proc Natl Acad Sci USA 96: 15032–15037], and Skts13 was identified as the Aurka gene using a conventional linkage in conjunction with haplotype analysis [Ewart‐Toland et al. 2003. Nat Genet 34: 403–412]. In the present study, we examined another wild‐derived outbred Mus musculus castaneus in which 10.3% of the analyzed SNPs showed heterogeneity among the colony. All mice examined were completely resistant to the two‐stage skin carcinogenesis protocol using 7.12‐dimethylbenz(a)anthracene (DMBA)/12‐O‐tetradecanoylphorbol‐13‐acetate (TPA), and this resistant phenotype was dominant when we crossed them with the highly susceptible strain FVB. By scanning F1 backcross progeny between M. m. castaneus and FVB, we found a highly significant linkage for tumor multiplicity on Chromosome 4, which was overlapped with the Skts‐fp1 locus, found in the previous study using FVB and PWK cross [Fujiwara et al. 2007. BMC Genet 8: 39]. The linkage was observed in all pedigrees from the five F1 founders, while the linkage for papilloma size on Chromosome 4 was mapped only in pedigrees from founders 1 and 2. By scanning the whole Chromosome 4 of the five F1 founders, founders 1‐ and 2‐specific haplotype block was found between D4Mit293 (20.6 Mbp) and D4Mit171 (22.4 Mbp). In this study we exploited the outbred nature of M. m. castaneus stock to identify a haplotype contributing to papilloma size on mouse Chromosome 4. These data illustrate the strength of using outbred mice in identification of the genetic component of a mouse complex trait such as the skin cancer‐susceptibility phenotype. © 2010 Wiley‐Liss, Inc.
Nicht aus einem Guss
Authors: Hartwig Andreas 
Published: May 2010

AbstractPraktisch alle natürlichen und synthetischen Materialien sind heterogen — seien es Perlmutt, Bäume, Polymere oder Hochleistungsstahl. Es stellt sich also die Frage, ob es so etwas wie ein Prinzip der Heterogenität gibt, das den Materialien ihre herausragenden Eigenschaften verleiht.
UHPLC: Verkaufsschlager oder Nischenprodukt?
Authors: Osterath Brigitte 
Published: May 2010

AbstractGerätehersteller wetteiferten auf der Analytica darum, wessen UHPLC‐Gerät den höchsten Druck verträgt und die schnellste Analyse liefert. Gleichzeitig äußerten kritische Stimmen, dass sich die Umstellung nur in Spezialfällen lohne, und warben mit alternativen HPLC‐Säulen für eine bessere Auflösung.
Proteomic analysis of field cancerization in pharynx and oesophagus: a prospective pilot study
Authors: Roesch‐Ely Mariana , Leipold Alexandra , Nees Matthias , Holzinger Dana , Dietz Andreas , Flechtenmacher Christa , Wolf Thomas , Zapatka Marc , Bosch Franz X 
Published: May 2010

Abstract‘Field cancerization’ in head and neck squamous cell carcinoma (HNSCC) is poorly understood and it may extend from the pharynx into the oesophagus. Both local recurrences and second primary carcinomas/second field tumours may originate from field cancerization. Our prospective pilot study aimed at the identification of patients suffering from field cancerization on the basis of mucosal protein profiles. Five mucosal biopsies from the oropharynx, hypopharynx and from three regions of the oesophagus were taken from 24 patients. Protein profiles were generated from the mucosal biopsies. After classifier learning, using the profiles of the patients without tumour diagnosis (n = 9), we were able to discriminate between the different mucosal sites and between healthy mucosa and HNSCC using tumour and healthy tissue samples. Mucosal biopsies of tumour patients (n = 15) revealed changes in the protein profiles similar to those in the tumours. During 42 months median follow‐up, six tumour patients experienced local recurrences and second field tumours, of which three occurred in the oesophagus. In all six cases, tumour relapse was correctly predicted by altered mucosal protein profiles (p = 0.007, Fisher's exact test, two‐tailed). Consequently, molecular field cancerization had a strong impact on progression‐free survival (p = 0.007, log‐rank test). Protein profiles of small diagnostic biopsies hold great promise to improve personalized risk assessment in HNSCC. Larger studies are needed to further substantiate these findings. Copyright © 2010 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
‘Evidence‐based medicine: the time has come to set standards for staging’. Is a radical overhaul really needed?
Authors: Sobin Leslie H , Compton Carolyn A , Gospodarowicz Mary , Greene Frederick L , Gunderson Leonard L , Jessup J Milburn , Wittekind Christian 
Published: May 2010

AbstractThis Invited Response addresses concerns and opinions expressed in an Invited Commentary, ‘Evidence‐based medicine: the time has come to set standards for staging’, by Quirke et al., published in this issue of The Journal of Pathology. Copyright © 2010 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Superhydrophobic films of UV‐curable fluorinated epoxy acrylate resins
Authors: Lin Yung‐Hsin , Liao Keng‐Huan , Huang Chih‐Kai , Chou Nai‐Kuan , Wang Shoei‐Shen , Chu Shu‐Hsun , Hsieh Kuo‐Huang 
Published: May 2010

AbstractPhotopolymerization processes are often used in industrial applications because of their solvent‐free formulations and various advantages over conventional thermal processes. Fluorinated monomers and oligomers yield coatings of great interest because of the peculiar characteristics of fluorine atoms: these coatings show hydrophobicity, chemical stability, weathering resistance, etc. Novel UV‐curable fluorinated epoxy acrylate oligomers were synthesized from 1H,1H‐perfluorohexan‐1‐ol, 1,6‐hexamethylene diisocyanate (HDI) and epoxy acrylate (EA). The HDI plays the role of a spacer group in the side chain between the EA backbone chain and the fluorinated segment. This new spacer containing a urethane moiety with long alkyl groups can exhibit a self‐organization effect through the formation of strong hydrogen bonding. This resulted in a stiffening of the whole HDI urethane–perfluoalkyl chain to form nanostructure surface segregation. The designed fluorinated EA with fluoroalkyl (C5F11) units in the side chain exhibited a contact angle of about 151°, which is in the superhydrophobic range. Copyright © 2010 Society of Chemical Industry