bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical trial recruitment of people who speak languages other than English: a Children’s Oncology Group report
Authors: Beauchemin Melissa P , Ortega Maria , Santacroce Sheila J , Robles Joanna M , Ruiz Jenny , Hall Anurekha G , Kahn Justine M , Fu Cecilia , Orjuela-Grimm Manuela , Hillyer Grace C , Solomon Samrawit , Pelletier Wendy , Montiel-Esparza Raul , Blazin Lindsay J , Kline Cassie , Seif Alix E , Aristizabal Paula , Winestone Lena E , Velez Maria C 
Published: June 2024

Abstract

Background
Persons who speak languages other than English are underrepresented in clinical trials, likely in part because of inadequate multilevel resources. We conducted a survey of institutions affiliated with the Children’s Oncology Group (COG) to characterize current research recruitment practices and resources regarding translation and interpretation services.

Methods
In October 2022, a 20-item survey was distributed electronically to institutions affiliated with COG to assess consent practices and resources for recruiting participants who speak languages other than English to COG trials. Descriptive statistics were used to summarize responses; responses were compared by institution size and type as well as respondent role.

Results
The survey was sent to 230 institutions, and the response rate was 60% (n = 139). In total, 60% (n = 83) of those respondents had access to short-form consent forms. Full consent form translation was required at 50% of institutions, and 12% of institutional review boards restricted use of centrally translated consent forms. Forty-six percent (n = 64) of institutions reported insufficient funding to support translation costs; 19% (n = 26) had access to no-cost translation services. Forty-four percent (n = 61) were required to use in-person interpreters for consent discussions; the most frequently cited barrier (56%) to obtaining consent was lack of available in-person interpreters. Forty-seven percent (n = 65) reported that recruiting persons who speak languages other than English to clinical trials was somewhat or very difficult.

Conclusions
Institutions affiliated with COG face resource-specific challenges that impede recruitment of participants who speak languages other than English for clinical trials. These findings indicate an urgent need to identify strategies aimed at reducing recruitment barriers to ensure equitable access to clinical trials.
(035) WOMEN IN PROSTHETIC UROLOGY: MENTORSHIP, SPONSORSHIP, AND CAREER ADVANCEMENT
Authors: Paulsen O , Orozco Rendon D , King S , Hehemann M , Ramasamy R , L  Bernie H 
Published: June 2024

Abstract

Introduction
Mentorship is a dynamic, reciprocal personal relationship in which a more experienced member of the organization (mentor), acts as a guide, role model, teacher, and sponsor of a less experienced person (mentee). Sponsorship involves the mentor making a personal investment in the advancement of the mentee. Women currently in and looking to enter prosthetic urology are not afforded the same quality or quantity of these dynamic relationships compared to men.

Objective
The goals of this manuscript are to discuss obstacles and barriers faced by women in prosthetic urology, highlight the benefits of mentorship and sponsorship in advancing the careers of women in this field, and provide recommendations for creating a more inclusive and supportive environment for women to excel in prosthetic urology.

Methods
Six authors carefully reviewed full-text, published articles related to the climate of [women in urology], [prosthetic urology], and available [mentorship], [sponsorship], and [leadership], and data from the 2022 American Urologic Association (AUA) census. Thirty-two sources were included.

Results
Urology and specifically, prosthetic urology, has a long history of being male-prominent. Several factors play into this truth, including gender roles, societal influences, implicit biases, medical history, and a lack of early exposure, mentorship, and sponsorship. Despite strides made in gender equity in medicine, women remain underrepresented in urology making up only 11.6% of practicing urologists in the United States. In subspecialties such as prosthetic urology, women make up even less of the pool. These factors also contribute to the lack of women in leadership positions. As of 2023, women occupy just 3 of the 13 board member positions and 7 of the 29 committee chair positions in the SMSNA.

Conclusions
Implementing successful mentorship involves recognizing the gender disparities that exist in prosthetic urology, having male mentors and sponsors, and breaking the traditional mentor-mentee hierarchies. Additionally, mentees can foster effective mentorship by establishing SMART goals and getting involved in women affinity groups. By creating an inclusive, diverse environment that not only welcomes, but mentors, and sponsors women, prosthetic urology can harness its full potential.

Disclosure
No.
(036) BASELINE CHARACTERISTICS OF PATIENTS UNDERGOING GENDER AFFIRMING HYSTERECTOMIES
Authors: De Moya A , Watson K , Rowen T 
Published: June 2024

Abstract

Introduction
Gender affirming hysterectomies (GAH) are one of the many interventions offered to people with uteruses who are seeking gender affirming care. Gender affirming care, especially hormones, has been shown to improve sexual satisfaction outcomes, but no research currently exists on sexual function or orgasm experience after gender affirming hysterectomy in particular. Post-hysterectomy sexual function has only been examined in cisgender populations, and has found mixed results on sexual health, wellness, and function. Research on sexual function and orgasm experience after GAH is needed to inform evidence-based recommendations and advance our understanding of sexual pleasure in a population that has historically been under-researched.

Objective
To achieve a better understanding of how gender affirming hysterectomies impact the experience of sex through a standardized analysis of orgasms and sexual function.

Methods
This project is a prospective study of patients receiving gender affirming hysterectomies at a single tertiary care center (November 2023-ongoing). Baseline characteristics (pre-hysterectomy) have been collected and analyzed via surveys asking about demographics, sexual practices, medical history, orgasm satisfaction (Orgasm Rating Scale) and sexual function (Transmasculine Sexual Functioning Index).

Results
We currently have 5 patients enrolled and anticipate a sample size of 30 participants by mid-February 2024. We plan to present pre-hysterectomy data describing participants’ overall sexual function and satisfaction. We anticipate a diversity of sexual practices and wellbeing.

Conclusions
There is a dearth in the current literature describing sexual function of individuals pursuing GAH. Further characterizing this population's pre-operative sexual practices and satisfaction will improve our ability to counsel patients considering GAH. Comparing this baseline data to sexual function post-GAH will provide insight into how GAH impacts ability to perform sexually and its influence on overall sexual satisfaction. This data will allow us to provide evidence-based recommendations regarding the impact of hysterectomy on orgasm and sexual function in patients seeking GAH.

Disclosure
No.
(062) IMPLEMENTING A VALIDATED SEXUAL DYSFUNCTION SCREENING TOOL AT AN INNER-CITY WOMEN’S HEALTH CLINIC
Authors: Zandvliet R , Wortel S , Hartnett J , Lindsay S 
Published: June 2024

Abstract

Introduction
The American College of Obstetricians and Gynecologists (ACOG) reports 43% of American women experience sexual health problems, including Female Sexual Interest and Arousal Disorder, Female Orgasmic Disorder, Genito–Pelvic Pain and Penetration Disorder, and Substance or Medication-Induced Sexual Dysfunction.

Objective
At Women’s Ambulatory Health Services (WAHS), an inner-city clinic associated with Hartford HealthCare, at which UConn Health ObGyn residents work, there is no routine screening in place for sexual dysfunction. This project aimed to implement the Female Sexual Function Index (FSFI) for screening for sexual dysfunction at this clinic to identify patients who may benefit from treatment.

Methods
We implemented the FSFI-short version, a six-question screening tool for sexual dysfunction that has been validated in English and Spanish and utilized in many countries on July 1st, 2022. Patients presenting for a new gynecologic visit or an annual gynecologic exam were asked to complete the screening tool. Patients who scored equal to or less than 18 on the FSFI-short version were identified as at risk for female sexual dysfunction and were offered referral to a health psychologist specializing in sexual dysfunction. We utilized the RE-AIM framework for implementation science to guide the implementation evaluation. We collected data on patients from July 1 through December 1, 2022. We collected patient demographics and implementation outcomes, including rate of survey completion, candidacy for referral and referral completion.

Results
196 surveys were reviewed between July 1st and December 1st of 2022. 44 surveys were excluded for various reasons, including not meeting study inclusion criteria or invalid responses. 152 screening forms were included and 45 patients screened positive. Subjective patient barriers were gathered from comments written directly onto the paper survey as well as quotes documented by their providers in the visit note. These subjective barriers included hesitancy to discuss sexual health and lacking knowledge that the gynecologist provider offers assessment and management for these disorders.

Conclusions
The introduction of the FSFI-sv at WAHS has both expanded the resources offered to patients, enhanced the environment surrounding topics of women’s health both between staff members as well as within the patient-provider relationship, and has unearthed multiple opportunities for improving the screening process, referral selection and work flow for sexual dysfunction amongst the patient population.

Disclosure
No.
(075) THE USE OF ONLINE EDUCATIONAL MODULES TO REDUCE FEMALE SEXUAL DYSFUNCTION
Authors: Suarez R , Shah M , Lynn M 
Published: June 2024

Abstract

Introduction
Sex is fundamental to overall health, well-being, and quality of life yet, the prevalence of female sexual dysfunction is alarmingly high. This could be attributed to multiple factors such as an overall dearth of evidence-based information detailing female anatomy, arousal, orgasm, and sexual disorders. In addition, many women face numerous obstacles that limit their access to a comprehensive sexual and reproductive health education. The unavailability and inaccessibility of knowledge regarding the female sexual experience can prevent many women from truly appreciating and understanding their bodies. This can lead to a variety of negative outcomes, including depression, anxiety, low self-esteem, and decreased well-being.

Objective
Several of these outcomes are most prevalent in young women; thus, it is critical that we educate this age group using delivery methods best suited for a young demographic.

Methods
In this study, we created a brief online educational module for women between the ages of 18 and 29 years old, which explained various aspects of the female sexual experience including female anatomy, orgasm responses, and masturbation. The module also shared resources women may use if they are experiencing issues regarding sex or pleasure. We expected to see greater female sexual literacy among women who completed the module (intervention) compared to those who did not (control). 13 women between the ages of 18 and 29 years old who were attending their annual gynecologic well-visit were recruited and randomly assigned to the intervention or control group.

Results
Although all participants from both groups rated sex education as important (N=13), less than half (N=5) reported having received formal sex education including female sexual functioning. Furthermore, only half (N=6) correctly disagreed when asked if the outer part of the female reproductive system was called “vagina.” However, post-test surveys showed no significant difference in knowledge between those who watched the module and those who did not. We attribute this to the sample size being too small, to the age range being too wide, and to the information presented in the module being too basic for this age group.

Conclusions
It is imperative that we not only continue to explore the female sexual experience, but that we also continue to improve ways to deliver that information. Further research on the use of online modules for sex education should consider its population’s degree of knowledge, limit their sample’s age range, and focus on issues its population commonly inquires about.

Disclosure
No.
(111) PLATELET-RICH PLASMA FOR IMPROVEMENT OF SEXUAL DYSFUNCTION: A PILOT STUDY
Authors: Kim S E 
Published: June 2024

Abstract

Introduction
Platelet-rich plasma has been widely used in various field of medicine. Some studies have shown that PRP helps improving sexual function, but most studies were conducted on men. There are also studies showing that it helps women’s sexual function, but it is very limited.

Objective
This study conducted to determine whether PRP was effective for women complaining of sexual dysfunction.

Methods
This retrospective study included 34 women who underwent PRP for improving sexual function from December 2022 to September 2023. Patients underwent a total of three procedures on schedules 0, 1, and 4 months. Before performing each procedure, a survey was conducted on questionnaire related to sexual dysfunction. The results of a total of 22 questions were analyzed by dividing them into sexual desire or sexual interest, sexual excitement, lubrication, orgasm, satisfaction with sexual life, pain during intercourse, and urinary incontinence.

Results
In the categories of sexual desire or sexual interest, sexual excitement, and satisfaction with sexual life scores showed a significant increase after PRP treatment (p &lt; 0.001, p &lt; 0.001, and p &lt; 0.003, respectively). There was a significant increase in orgasm between the first and third treatments (p &lt; 0.021), but it was not statistically significant overall. Symptoms related with lubrication, pain, and urinary incontinence all improved, but did not show statistical significance.

Conclusions
This study demonstrated that PRP improved some categories of sexual dysfunction.

Disclosure
No.
(116) SUBJECTIVE AND GENITAL SEXUAL RESPONSE IN FEMALE BREAST CANCER SURVIVORS: RESULTS FROM A PSYCHOPHYSIOLOGY STUDY
Authors: Grosse-Rueschkamp M S , Dörfler C , Tissen-Diabaté T , Kronthaler S , Beier K M , Hatzler L 
Published: June 2024

Abstract

Introduction
Sexual dysfunction is a prevalent concern affecting more than 70% of female breast cancer survivors, casting a substantial shadow on their quality of life. Beyond the physical impact of cancer and its treatments, the emotional and psychological toll of sexual dysfunction introduces additional challenges, amplifying stress levels and undermining overall well-being. Acknowledging the profound implications of sexual dysfunction in this group and the absence of therapies, there is an urgent need to delve deeper into the intricacies of its manifestations.

Objective
This study aimed to gather preliminary data on psychophysiological aspects of sexual function in premenopausal breast cancer patients undergoing antihormonal therapy and compare them with a healthy control group. Exploring sexual arousal in breast cancer patients may unveil potential targets for innovative treatment strategies to address sexual dysfunction in this population.

Methods
Participants were prescreened during a telephone interview. We included 40 premenopausal breast cancer survivors with an age range of 29 to 57 years (M = 43.5, SD = 6.36) on current hormonal treatment and 20 healthy controls with an age range of 22 to 35 (M = 27.55, SD = 3.19). Physiological measures (VPA and HRV), subjective sexual arousal (SSA) and self-reported orgasm were assessed in response to audiovisual stimuli and vibrotactile clitoral stimulation sexual stimuli in breast cancer survivors and healthy controls. Self-reported measures like the Female Sexual Function Index (FSFI), the Sexual Self-Esteem Inventory (SSEI) und the PROMIS29 were incorporated. Data were analyzed using 2-level mixed effect models.

Results
No significant differences in VPA scores were observed between healthy controls and breast cancer survivors. Both groups exhibited a greater genital response to clitoral vibrator use than to visual stimuli. Group differences emerged in SSA and HRV, with higher SSA and lower HRV being detected. Breast cancer survivors climaxed less frequently than healthy controls and had significantly lower self-reported sexual function.

Conclusions
Physiological measures of arousal in breast cancer survivors were comparable to healthy controls and only subjective arousal differed. This finding indicates that subjective arousal should be further explored as the focus of intervention and treatment methods for breast cancer patients experiencing sexual dysfunction. Our findings underscore the importance of tailored strategies that resonate with individual narratives, acknowledging the emotional intricacies of post-cancer sexual well-being. This study not only contributes to scientific knowledge but also calls for a compassionate and personalized treatment paradigm, enriching the landscape of survivorship care.

Disclosure
Yes, this is sponsored by industry/sponsor: WOW Tech GmbH
Clarification: No industry support in study design or execution.
(127) TRAUMA INFORMED CARE TO REDUCE ANTEPARTUM COMPLICATIONS IN SURVIVORS OF TRAUMA
Authors: Low A 
Published: June 2024

Abstract

Introduction
Life trauma permeates through society and across cultures. It impacts the individual, community, and society. Trauma may include but is not limited to adverse childhood experiences (ACEs), sexual assault and violence, domestic violence, and interpersonal violence (IPV). In the United States, 1 in 3 women experience physical IPV, 1 in 4 experience sexual assault, and 17% of adults have experienced 4 or more ACEs (CDC 2022, 2023). Experiencing trauma leads to a cascade of effects that infiltrate every aspect of life and causes higher levels of chronic stress. In those who are pregnant or giving birth, a history of trauma, particularly sexual assault, leads to adverse antepartum outcomes.

Objective
After this presentation, the learner will be able to: 1. Define trauma (ACEs, sexual assault, DV, IPV). 2. State the signs and symptoms of trauma. 3. Identify the antepartum complications associated with a history of trauma. 4. Explain the impact that a history of sexual assault has on the birth giver. 5. Define trauma informed care. 6. Identify the components of trauma informed care. 7. State the importance of using trauma informed care as a midwife and WHNP.

Methods
The methods used to address this topic include a literature review and podium style presentation of findings.

Results
Main findings include increased rates of miscarriage, preterm birth, post traumatic stress disorder, placental abruption, premature rupture of membranes, and low birth weight in pregnant survivors of past trauma. Additionally, the dynamic interplay between the Social Determinants of Health and violence experienced during pregnancy must be considered. Low household income, racism, lack of social support, as well as food and housing insecurity increased rates of intimate partner violence experienced during pregnancy. Trauma informed care has been shown to reduce psychological symptom severity and has been integrated into midwifery care to attempt to reduce these outcomes and prevent further traumatization of the client.

Conclusions
As pregnancy and childbirth are intimate and personal in nature, using a trauma informed model of care is crucial to identifying clients with trauma histories and caring for them in a manner that is cognizant of their lived experiences and potential antepartum outcomes. Future providers must receive adequate education and training regarding trauma informed care in an effort to prevent adverse outcomes and prevent re-traumatization of their clients.

Disclosure
No.
The properties of AGN in dwarf galaxies identified via SED fitting
Authors: Bichang’a B , Kaviraj S , Lazar I , Jackson R A , Das S , Smith D J B , Watkins A E , Martin G 
Published: June 2024

ABSTRACT
Given their dominance of the galaxy number density, dwarf galaxies are central to our understanding of galaxy formation. While the incidence of active galactic nuclei (AGN) and their impact on galaxy evolution have been extensively studied in massive galaxies, much less is known about the role of AGN in the evolution of dwarfs. We search for radiatively efficient AGN in the nearby (0.1 &lt; z &lt; 0.3) dwarf (108 M⊙ &lt; M⋆ &lt; 1010 M⊙) population, using spectral energy distribution fitting (via prospector) applied to deep ultraviolet to mid-infrared photometry of 508 dwarf galaxies. Around a third (32 ± 2 per cent) of our dwarfs show signs of AGN activity. We compare the properties of our dwarf AGN to control samples, constructed from non-AGN, which have the same distributions of redshift and stellar mass as their AGN counterparts. Kolmogorov–Smirnov tests between the AGN and control distributions indicate that the AGN do not show differences in their distances to nodes, filaments, and nearby massive galaxies from their control counterparts. This indicates that AGN triggering in the dwarf regime is not strongly correlated with local environment. The fraction of AGN hosts with early-type morphology and those that are interacting are also indistinguishable from the controls within the uncertainties, suggesting that interactions do not play a significant role in inducing AGN activity in our sample. Finally, the star formation activity in dwarf AGN is only slightly lower than that in their control counterparts, suggesting that the presence of radiatively efficient AGN does not lead to significant, prompt quenching of star formation in these systems.
Transition from decaying to decayless kink oscillations of solar coronal loops
Authors: Nakariakov Valery M , Zhong Yu , Kolotkov Dmitrii Y 
Published: June 2024

ABSTRACT
The transition of an impulsively excited kink oscillation of a solar coronal loop to an oscillation with a stationary amplitude, i.e. the damping pattern, is determined using the low-dimensional self-oscillation model. In the model, the decayless kink oscillations are sustained by the interaction of the oscillating loop with an external quasi-steady flow. The analytical solution is based on the assumption that the combined effect of the effective dissipation, for example, by resonant absorption, and interaction with an external flow, is weak. The effect is characterized by a dimensionless coupling parameter. The damping pattern is found to depend upon the initial amplitude and the coupling parameter. The approximate expression shows a good agreement with a numerical solution of the self-oscillation equation. The plausibility of the established damping pattern is demonstrated by an observational example. Notably, the damping pattern is not exponential, and the characteristic decay time is different from the time determined by the traditionally used exponential damping fit. Implications of this finding for seismology of the solar coronal plasmas are discussed. In particular, it is suggested that a very rapid, in less than the oscillation period, decay of the oscillation to the stationary level, achieved for larger values of the coupling parameter, can explain the relative rareness of the kink oscillation events.