bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre-injection local anesthesia does not affect experienced pain in intra-articular hip injections
Authors: Albagli Assaf , Rath Ehud , Druckmann Ido , Efrima Ben , Kazum Efi , Parnes Nata , Sandler Alexis B , Tyler John , Amar Eyal 
Published: February 2025

BACKGROUND
Intra-articular hip injections (IAHIs) are commonly used for diagnostic and therapeutic purposes but are often associated with patient anxiety and fear. The disparity between anticipated and experienced pain during IAHIs and the role of pre-injection local anesthesia in pain modulation remains unclear.
AIM
To investigate the difference between anticipated and experienced pain during IAHIs and the impact of pre-injection local anesthesia.
METHODS
This prospective study enrolled 60 patients undergoing IAHI, 30 receiving pre-injection superficial local anesthesia and 30 serving as a control group without pre-injection local anesthesia. Pain levels were assessed using numeric rating scales.
RESULTS
Patients significantly overestimated anticipated pain compared to experienced pain (6.43 ± 2.48 vs 3.68 ± 2.37, P < 0.001). Pre-injection local anesthesia did not significantly reduce experienced pain (3.19 ± 2.38 vs 4.20 ± 2.29, P = 0.130).
CONCLUSION
Patients overestimate anticipated pain during IAHIs. Pre-injection local anesthesia does not reduce experienced pain.
Percutaneous transforaminal endoscopic treatment of gas-containing pseudocyst compressing the L5 nerve root: A case report
Authors: Jiang Zhen-Xian , Ren Ji-Bin , Li Yu-Cai , Chen Lei 
Published: February 2025

BACKGROUND
Gas-containing pseudocysts rarely cause of lumbar radiculopathy. This report describes successful treatment of a gas-containing pseudocyst using percutaneous transforaminal endoscopy.
CASE SUMMARY
A 48-year-old man presented with severe pain and numbness in his right leg, which worsened upon walking or weight bearing. Computed tomography and magnetic resonance imaging revealed a gas-containing cyst compressing the left L5 nerve root at the L4–5 level. The pseudocyst was successfully removed using a percutaneous transforaminal endoscopic discectomy. Vivid and clear endoscopic imaging of the pseudocysts was performed intraoperatively. The patient experienced immediate pain relief and was discharged one day after the operation. The patient returned to work. Moreover, numbness in the right leg returned to normal within 6 months. At the one-year follow-up, there was no symptoms recurrence.
CONCLUSION
Transforaminal endoscopy offers excellent surgical visualization and facilitates meticulous operative manipulation, making it a minimally invasive approach for treating gas-containing pseudocysts in the intervertebral foramen.
Return to work and resumption of driving after anterior minimally invasive total hip arthroplasty
Authors: Ishikura Hisatoshi , Masuyama Yuji , Fujita Sho , Tanaka Takeyuki , Tanaka Sakae , Nishiwaki Toru 
Published: February 2025

BACKGROUND
Return to work (RTW) and resumption of driving (ROD) are critical factors that influence postoperative quality of life in patients undergoing total hip arthroplasty (THA). However, few studies have focused on the minimally invasive (MIS) approach and its effect on these outcomes.
AIM
To investigate RTW and ROD's timelines and influencing factors following anterior MIS-THA.
METHODS
A retrospective analysis was conducted on 124 patients who underwent anterior MIS-THA. Data on the demographics, occupational physical demands, and RTW/ROD timelines were also collected. Clinical outcomes were measured using standardised scoring systems. Statistical analyses were performed to evaluate the differences between the groups based on employment status and physical workload.
RESULTS
Among employed patients, the RTW rate was 94.7%, with an average return time of five weeks. The average ROD time was 3.5 weeks across all patients. Despite similar postoperative clinical scores, RTW time was significantly influenced by occupations' physical workload, with heavier physical demands associated with delayed RTW.
CONCLUSION
Anterior MIS-THA facilitates early RTW and ROD, particularly in occupations with lower physical demands. These findings highlight the importance of considering occupational and physical workload in postoperative care planning to optimize recovery outcomes.
Perceptions and experiences with academic group work in online and in-person classroom contexts: Perspectives across levels of undergraduate study
Authors: Vogel Natasha , Wood Eileen , Pinto Sabrina 
Published: February 2025

Group work is a commonly used and highly regarded learning tool in tertiary education. While previous research has examined collaboration within higher education contexts, no study has investigated student preferences and experiences across different years of study. This is essential for a better understanding of how to effectively integrate collaborative learning into the undergraduate curriculum. The present study surveyed first year, second year and senior (3rd and 4th year) undergraduate students (n = 100 per group) to gather insights regarding their experiences with collaborative learning as a function of year of study and in both in-person and online contexts. Overall, preferences regarding group composition (e.g., group size) and experiences regarding group work (e.g., efficiency, motivation, satisfaction, stress) were consistent across the year of study. However, notable shifts in experiences were observed, particularly from first to second year, with respect to instructor-related variables (i.e., group formation strategies, leadership opportunities) and student-related variables (i.e., perceived difficulty producing assignments, level of collaboration in groups, learning experiences and enjoyment). Some differences were also observed between in-person and online contexts. Implications for future studies and instructional design are discussed.
Quasivrijwillige mediation
Authors: de Roo Annie , Jagtenberg Rob 
Published: February 2025

Quasi voluntary mediation – A short comment on the Dutch Mediation Bill 2013
On 26 May 2013 Ard van der Steur, Netherlands MP for the liberal democrats, introduced a cluster of three mediation bills to secure the status of mediation as a sound alternative to traditional in-court adjudication in civil and administrative disputes. Although the starting point in these bills is that mediation should take place on a voluntary basis, there are some arrangements that may result in quasi compulsory mediation. One such arrangement is that the judge, on his own motion, may refer parties to mediation. Also parties have to proof that they first have attempted to settle their dispute through mediation and if not, why not.
Het melden van ongewone voorvallen
Authors: Maas-Cooymans M.M.C. , Ebben B. 
Published: February 2025

Het melden van ongewone voorvallen
De auteurs bespreken de meldplicht voor ongewone voorvallen in een inrichting. De algemene verplichting op grond van artikel 17.1 Wm wordt vergeleken met de aanvullende verplichtingen in de omgevingsvergunning. Daarvoor wordt de reikwijdte van de wettelijke bepaling besproken en de aanvullende rol die vergunningsvoorschriften nog kunnen spelen. Tot slot wordt aandacht besteed aan de wijziging van artikel 17.1 Wm die voorschrijft dat in bepaalde gevallen het productieproces in een inrichting moet worden stilgelegd.
Meer of minder afval?
Authors: Tieman J.R.C. 
Published: February 2025

Meer of minder afval? Het onderscheid tussen afvalstoffen en grondstoffen onder de vernieuwde Kaderrichtlijn Afvalstoffen 2008/98/EG
De vernieuwde Kaderrichtlijn Afvalstoffen verscheen eind 2008 in het Europese publicatieblad. Vijf jaar na dato kan aan de hand van de rechtspraak over het begrip afvalstof en de in de richtlijn opgenomen uitzonderingen de balans worden opgemaakt: is het met de nieuwe richtlijn in de hand inderdaad makkelijker geworden om afvalstoffen van (secundaire) grondstoffen te onderscheiden? De conclusie is dat dit maar zeer ten dele is gelukt, en dat het nog steeds vooral aan de rechter is om de scherpe randjes van het afvalstoffenbegrip weg te vijlen. Wel lijkt het zo dat het begrip afvalstof anno 2014 minder ruim is dan in 2000 na het arrest ARCO Chemie misschien nog werd gedacht.
Assessment of Factors Influencing the Stability of the Banking System: Experience of the European Union Countries
Authors: Meshcheriakov Andrii , Maslov Anatoliy , Saienko Grygorii , Antoniuk Oksana , Sunduk Tetiana 
Published: February 2025

Introduction: In modern developed European countries, the banking system reflects the economy's state and financial sector efficiency. Its stability significantly impacts the financial system and economic growth. Banking institutions act as intermediaries between sectors like trade, manufacturing, agriculture, and consumers, underscoring their critical role. Aim: This study aims to identify factors influencing banking system stability by analyzing the European Union's banking experience. Methods: A statistical analysis was conducted to determine the key factors affecting stability and prioritize those requiring regulatory focus. The research employed general scientific methods (analysis, synthesis, generalization, systematization) and a specific method—a multiple regression model—to identify factors ensuring financial stability. Results and conclusions: Findings reveal regional disparities and instabilities in the distribution of major banks across EU countries. This highlights the need for proactive fiscal stability measures. The multiple regression analysis identified significant determinants of banking stability, including capital cost and accessibility, investment activity, financial stability risks, digital security, and data protection. These insights emphasize the importance of targeted regulatory efforts to enhance the EU banking sector's resilience and sustainable growth
Clinical characteristics and treatment outcomes in multiple sclerosis patients treated with anti-CD20s who switched to fumarates: a retrospective analysis of a US healthcare claims database
Authors: Ben-Zacharia Aliza B , Feng Jenny J , Moss Brandon P , Belviso Nicholas , Yu Zhang  , Branco Filipe , Mendoza Jason P , Lewin James B , Sarah M England  
Published: February 2025

Aim:
Anti-CD20 monoclonal antibodies and fumarates are common multiple sclerosis (MS) disease-modifying therapies (DMTs). Data on switching from anti-CD20s to other DMTs are limited. This retrospective, observational study of the US Komodo Health Sentinel claims database aimed to evaluate a de-escalation strategy in a real-world cohort, comparing clinical characteristics, relapses, healthcare encounters (HCEs) and healthcare costs (HCCs) between patients aged ≥18 years with stable MS who switched from anti-CD20s to fumarates (‘Switchers’) versus patients who stayed on anti-CD20s (‘Stayers’).
Materials & methods:
Patients with MS (diagnosed 1 January 2015–31 August 2022) were propensity score matched 5:1 (Stayers:Switchers) and followed from index to end of study; end of insurance eligibility; >45-day gap in index DMT; or DMT switch. Primary outcomes were clinical characteristics and claims-based annualized relapse rate (ARR). Rates of HCEs and HCCs were estimated.
Results:
Baseline characteristics were well balanced between cohorts (Stayers, n = 540; Switchers, n = 108). Mean (SD) duration of post-index follow-up was 341.4 (250.0) days for both cohorts. Mean (SD) ARR was 0.08 (0.41; Stayers) versus 0.14 (0.5; Switchers; p = 0.3). Twenty-one Stayers (3.9%) and 1 Switcher (0.9%) were hospitalized for infections, with mean stays of 9.9 and 1 day, respectively. Mean annualized all-cause HCEs were similar between cohorts; annualized inpatient infection-related HCEs were higher for Stayers versus Switchers (mean difference: -0.05; p = 0.005). Annualized all-cause HCCs were similar between cohorts; Switchers had lower annualized infection-related HCCs overall (mean difference: -$2412; p = 0.002) and in the inpatient setting (mean difference: -$2325; p = 0.002).
Conclusion:
After 1 year, no significant differences in ARR emerged between cohorts. Switchers experienced lower inpatient infection-related HCEs, shorter inpatient infection-related hospital stays and lower overall infection-related HCCs.
Eculizumab or ravulizumab treatment effect in people with neuromyelitis optica spectrum disorder: a plain language summary of three studies
Authors: Damasceno Alfredo , Marrodan Mariano 
Published: February 2025

What is this summary about?
Neuromyelitis optica spectrum disorder (NMOSD for short) is a rare autoimmune health condition, meaning that the body's natural defense system (the immune system) attacks the body's own tissues. This summary describes NMOSD and the results of three studies of the effects of treatment with two medicines called eculizumab and ravulizumab. Eculizumab and ravulizumab are approved to treat people with a type of NMOSD called AQP4-Ab+ NMOSD. The three studies included in this summary are the PREVENT and CHAMPION-NMOSD clinical studies and a study done in everyday clinical practice in Japan.

What are the key conclusions from these studies?
The PREVENT study was a phase 3 study (a large study testing safety and effectiveness of a treatment before it is approved) with three parts. The PREVENT main study compared eculizumab to a placebo (a treatment with no active ingredients, used to test how well a new treatment works). A long-term follow-up study assessed the safety and effectiveness of eculizumab over time, without a placebo group. Another long-term follow-up focused on people taking eculizumab alone, without other immunosuppressive treatments. The CHAMPION-NMOSD study was another phase 3 study testing ravulizumab, a treatment based on eculizumab but given less often, using the placebo group from the PREVENT study for comparison. A daily clinical practice study with eculizumab in Japan looked at how eculizumab works in everyday medical practice (outside of controlled clinical trials) after the medication was already approved. The studies found eculizumab and ravulizumab to be safe and effective for preventing relapses in AQP4-Ab+ NMOSD. More than 95% of people treated with these medicines stayed relapse-free during the months or years of the studies follow-up periods. Most people reported side effects that were mild or moderate. The most common side effects were headache, runny nose or sore throat (nasopharyngitis), and infections in the upper respiratory system. The daily practice study confirmed that eculizumab works well in everyday medical practice.

What do the findings of the study mean?
These studies suggest that eculizumab and ravulizumab are safe and effective treatments for people with AQP4-Ab+ NMOSD. Eculizumab may help reduce or stop the need for other treatments that weaken the immune system (immunosuppressive therapies). These treatments help people maintain their ability to carry out daily activities and their quality of life.
effect of cation ordering on the structure, electrical and electronic properties of cubic spinel LiNi0.5Mn1.5O4
Authors: Edi Yasa Ardiansyah  , Mohd Sobri Idris  , Rozana Aina Maulat Osman  , Fahmi Fahmi  
Published: February 2025

In this paper, we present the investigation of the impact of cation ordering on the structural, electrical, and electronic properties of a cubic spinel LiNi0.5Mn1.5O4. Rietveld refinement using X-ray diffraction (XRD) data reveals that LiNi0.5Mn1.5O4 annealed at 700 °C adopts a well-ordered atomic arrangement in cubic spinel (SG = P4332). Then, it is transformed to a disordered cubic spinel (SG = Fd-3m) at higher temperatures (> 800 °C). Impedance spectroscopy is employed to evaluate the dielectric and electrical properties in the temperature range of 0 to 25oC within the frequency range between 10 Hz and 100 kHz. The Cole-Cole plot indicates that grain boundaries contribute significantly to electrical conductivity and that bulk resistance decreases with increasing temperature. The AC conductivity analysis shows that the electrical conductivity of well-ordered and disordered cubic spinel LiNi0.5Mn1.5O4 exhibits thermal activation and obeys Jonscher's universal power law. Furthermore, the electronic properties of cubic spinel LiNi0.5Mn1.5O4 with the space groups of Fd-3m and P4332 are investigated using the density functional theory (DFT) plane-wave method. The electronic analysis of the cubic spinel LiNi0.5Mn1.5O4 (SG = Fd-3m) indicates stronger bonding between oxygen and transition metal elements compared to the LiNi0.5Mn1.5O4 (SG = P4332) structure. Therefore, LiNi0.5Mn1.5O4 with the Fd-3m space group exhibits high structural stability, making it a favourable cathode material for high-voltage rechargeable lithium-ion batteries.
Peranan Teknologi dalam Mendukung Perekonomian di Desa Mojowatesrejo
Authors: Wyda Lusiana  , Alvia Nur Jannah  , Miftakhul Fitriyah  , Rizka Lailiya Tasya  , Robi’atul Adawiyah  , Rosi Diah Bela  , Meta Silvi Rosalia  , Rafif Farrydika  , Risky Nurus Sobah  , Eko Setiyo Budiono  , Juan Ariwangsa  , Aditya Indra Wardana  , Krisna Laksana Putra  , Dhena Mustikawati  , Orka Maya Armayudha  , Ratna Dewi Rama Diningtias  , Adam Wirasunu  , Mochammad Nur Mahmudi  , Tazkia Rizki Adillah  , Hari Widiastuti  , Indyka Giran Mahardani  , Indah Lestiana  , Aldo Putra Pratama  
Published: February 2025

Technology is a system used to market via social media in the current era of globalization. The socialization activity with the theme “The Role of Technology in Improving the Economy in Mojowatesrejo Village” was held on December 13, 2024 at the Mojowatesrejo Village hamlet hall. This socialization activity is carried out to teach the public about the role of digital technology, not only that, but also to carry out socialization and direct practice in using digital through social media. Business activities in Mojowatesrejo village include the agricultural, livestock and craft sectors. After learning about the important role of digital technology, people were very enthusiastic and began to actively use social media to promote their products.
Sozialpartnerschaft – ein zeitgemäßes Instrument der Konfliktlösung?
Authors: Zotter Thomas , Marterbauer Markus 
Published: February 2025

Die Sozialpartnerschaft hat entscheidend zum wirtschaftlichen Aufstieg Österreichs und zum sozialen Frieden beigetragen und gilt als Schlüsselfaktor für den Erfolg des österreichischen Wirtschaftsmodells. Es ist jedoch eine schleichende Abnahme ihrer Bedeutung und Konfliktlösungskompetenz zu beobachten, vor allem bei Herausforderungen wie der Klimakrise und steigender Ungleichheit. Die Kritik an der Sozialpartnerschaft nimmt zu, besonders von neoliberaler und populistischer Seite, und unter den veränderten politischen Mehrheits- und Machtverhältnissen sowie geänderten internationalen Rahmenbedingungen wird der Interessenausgleich komplizierter. Gleichzeitig genießt die Sozialpartnerschaft im Allgemeinen hohes Vertrauen und Zustimmung in der Bevölkerung wie auch bei den Mitgliedern der beteiligten Organisationen. Die Kollektivvertragsverhandlungen bleiben weiter ein stabiler Pfeiler der Sozialpartnerschaft, es braucht aber darüber hinaus angesichts der fundamentalen Zunahme der Unsicherheit in Wirtschaft und Gesellschaft sowie der immer drängenderen Krisen unseres Wirtschaftssystems kompetente und verlässliche Institutionen, die Stabilität geben und ausgewogene Reformen tragen.
D. M. Walsh’s Organisms, Agency, and Evolution // Reviewed by John Dupré
Authors: BJPS The 
Published: February 2025

Next Home Previous Organisms, Agency, and Evolution D. M. Walsh
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Organisms, Agency, and Evolution
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D. M. Walsh Cambridge: Cambridge University Press, 2016, £ 64.99 ISBN 9781107122109 The mantle of heir to Darwin’s famous theory of evolution by natural selection is generally claimed by the so-called neo-Darwinism that derives from the Modern Synthesis, announced
Integral orthogonal bases of small height for real polynomial spaces
Authors:   Department of Mathematics, 850 Columbia Avenue, Claremont McKenna College, Claremont, CA 91711, Fukshabsky Lenny 
Published: February 2025

Let \( \mathcal{P}_N(\mathbb{R}) \) be the space of all real polynomials in \( N \) variables with the usual inner product \( \langle \cdot, \cdot \rangle \) on it, given by integrating over the unit sphere. We start by deriving an explicit combinatorial formula for the bilinear form representing this inner product on the space of coefficient vectors of all polynomials in \( \mathcal{P}_N(\mathbb{R}) \) of degree \( \leq M \). We exhibit two applications of this formula. First, given a finite-dimensional subspace \( V \) of \( \mathcal{P}_N(\mathbb{R}) \) defined over \( \mathbb{Q} \), we prove the existence of an orthogonal basis for \( (V, \langle \cdot, \cdot \rangle) \), consisting of polynomials of small height with integer coefficients, providing an explicit bound on the height; this can be viewed as a version of Siegel’s lemma for real polynomial inner product spaces. Secondly, we derive a criterion for a finite set of points on the unit sphere in \( \mathbb{R}^N \) to be a spherical \( M \)-design.