bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Displaced in the name of Religion’: Girl child abuse and community healthcare workers' response to women crying for help in IDP camps in North Central, Nigeria
Authors: Uroko Favour Chukwuemeka , Obiorah Mary Jerome 
Published: May 2024

AbstractThis study examines girl child abuse in an internally displaced people's camp in north‐central Nigeria and the response of community health workers. The conflict in Benue State is caused by religious differences between the natives (Tiv people) and the invading Fulani herdsmen. During these conflicts, women and girls were displaced, and they were kept in internally displaced persons (IDPs) located in different parts of the state. Literature has been extensively written on internal displacement in Nigeria, but none has been able to elucidate the health needs of girls and the various abuses girls and women are suffering in IDP camps. In this study, literature was extended (1) to explore the environment of the girl child in IDP camps, (2) to identify reasons for the abuse of the girl child in IDP camps, (3) to investigate the impacts of the abuse on the girl child in IDP camps and (4) to investigate how healthcare workers could be used to alleviate the plight of girl children in IDP camps. This is a qualitative case study, with data obtained from relevant academic literature and personal observation. The data were analysed using content analysis. Findings reveal that the girl child is suffering from psychological, economic and health challenges due to the various forms of abuse they are going through. Following the devastation in Benue State, healthcare workers from the community relocated to neighbouring states. There is a need to recall those healthcare workers and provide them with the necessary materials to assist girls in IDP camps. Recommendations are discussed.
How is teaching quality related to achievement emotions in secondary low‐ and high‐achieving students: A cross‐sectional study in Chinese mathematics classrooms
Authors: Chen Xin 
Published: May 2024

AbstractBackgroundPast studies clarified the relationship between dimensions of teaching and achievement emotions. However, more information is needed about the underlying process behind this relationship among students with different mathematical abilities.AimsThis study examined the association between students' perceived teaching quality and achievement emotions in Chinese mathematics classrooms, focusing on students with different mathematics achievements.SamplesThere are 1045 secondary school students (49.1% girls; Mage = 13.90, SD = .84) from Chinese mathematics classrooms in the present study.MethodsA multi‐group structural equation model was adopted to test the relationship between teaching quality and achievement emotions between low‐ and high‐achieving students.ResultsControl‐value appraisals mediated in teacher support and achievement emotions in both student groups. At the same time, control‐value appraisals failed to mediate cognitive activation and achievement emotions in low‐achieving students, while the mediating effect of control‐value appraisals was identified in high‐achieving students. Besides, classroom management was related to achievement emotions via academic value only in low‐achieving students. In contrast, it was related to achievement emotions via control‐value appraisals in high‐achieving students.ConclusionsThe results clarified the mediation roles of control‐value appraisals in teaching quality and achievement emotions in students with low‐ and high‐achieving achievements. Similarities and differences were also identified between the two student groups. Teacher support was beneficial to students' positive emotions while classroom management helped to lessen students' negative emotions. High‐achieving students benefited more from activating teaching compared with low‐achieving students.
Whole‐blood transcriptome analysis reveals distinct gene expression signatures in paediatric patients with sickle cell anaemia before and after exercise
Authors: Plaza‐Florido Abel , Liem Robert I. , Haddad Fadia , Radom‐Aizik Shlomit 
Published: May 2024

SummarySickle cell anaemia (SCA) patients display elevated levels of circulating pro‐inflammatory cytokines and endothelial activation markers compared to healthy peers. The impact of exercise on the pro‐inflammatory state in SCA remains unclear. This study aimed to characterize the whole‐blood transcriptome profile in response to an acute bout of exercise in paediatric SCA patients. Twenty‐three SCA participants (13 ± 3 years, 52% girls) and 17 healthy controls (14 ± 3 years, 29% girls) performed eight 2‐min bouts of cycle ergometry interspersed with 1‐min rest intervals. Whole‐blood transcriptome profile (RNA‐seq) was performed before and after exercise. At baseline, gene pathways associated with gas transport in erythrocytes were up‐regulated in SCA patients compared to controls. Following exercise, gene pathways associated with innate immunity were altered in both groups. Interaction analyses revealed 160 annotated genes (101 up‐ and 59 down‐regulated) that differentially altered by exercise in SCA patients. Moreover, genes that exhibited a blunted response to exercise in SCA patients were enriched in the IL‐17 signalling pathway, suggesting an impaired innate immune response to exercise. This data will contribute to the development of evidence‐based exercise prescription guidelines for this patient population.
The neuropharmacological properties of α‐pyrrolidinobutiothiophenone, a new synthetic cathinone, in rodents; role of the dopaminergic system
Authors: Kim Oc‐Hee , Jeon Kyung Oh , Kim Gihyeon , Jang Choon‐Gon , Yoon Seong Shoon , Jang Eun Young 
Published: May 2024

AbstractBackground and Purposeα‐Pyrrolidinobutiothiophenone (α‐PBT) is a chemical derivative of cathinone, a structural analogue of amphetamine. Until now, there have been a few previous neurochemical or neurobehavioural studies on the abuse potential of α‐PBT.Experimental ApproachWe examined the abuse potential of α‐PBT by measuring psychomotor, rewarding, and reinforcing properties and methamphetamine‐like discriminative stimulus effects in rodents using locomotor activity, conditioned place preference, self‐administration, and drug discrimination studies. To clarify the underlying neuropharmacological mechanisms, we measured dopamine levels and neuronal activation in the dorsal striatum. In addition, we investigated the role of the dopamine D1 receptor or D2 receptors in α‐PBT‐induced hyperlocomotor activity, conditioned place preference, and the methamphetamine‐like discriminative stimulus effect of α‐PBT in rodents.Key Resultsα‐PBT promoted hyperlocomotor activity in mice. α‐PBT induced drug‐paired place preference in mice and supported self‐administration in rats. In a drug discrimination experiment, α‐PBT fully substituted for the discriminative stimulus effects of methamphetamine in rats. Furthermore, α‐PBT increased dopamine levels and c‐Fos expression in the dorsal striatum of mice, which was associated with these behaviours. Finally, pretreatment with the D1 receptor antagonist SCH23390 or the D2 receptors antagonist eticlopride significantly attenuated acute or repeated α‐PBT‐induced hyperlocomotor activity, place preference, and the methamphetamine‐like discriminative stimulus effects in rodents.Conclusions and ImplicationsThese findings suggest that α‐PBT has abuse potential at the highest dose tested via enhanced dopaminergic transmission in the dorsal striatum of rodents. The results provide scientific evidence for the legal restrictions of the recreational use of α‐PBT.
Contact sensitization and self‐reported eczema in Swedish painters with occupational exposure to isothiazolinones
Authors: Edlund Maria , Holm Mathias , Inerot Annica , Långsved Linda , Dahlman‐Höglund Anna , Hagvall Lina 
Published: May 2024

AbstractBackgroundDue to an increasing occupational usage of isothiazolinone (IT)‐containing preservatives, and their potential to cause skin sensitization and allergic contact dermatitis, that is, chronic disease, there is a need for more knowledge on how highly exposed workers are affected.ObjectivesThe overall objective was to explore dermatological symptoms of potentially long‐lasting or chronic character in Swedish painters.MethodsBuilding painters from western and southern Sweden were initially invited to perform a questionnaire on occurrence of skin symptoms. Participants with affirmative responses, and the right inclusion criteria, were further invited to patch testing with four different ITs: benzisothiazolinone (BIT), methylisothiazolinone, methylchloroisothiazolinone and octylisothiazolinone.ResultsThere was a tendency towards higher occurrence of positive patch test reactions among the painters compared with occupationally unexposed registry patients; however, not statistically significant differences. BIT was the substance most frequently causing positive test results in both groups. The occurrence of adult‐onset eczema was higher in painters than in the control group of electricians, and just shy of statistical significance concerning any of several skin locations (face/legs/arms/hands).ConclusionBuilding painters present with positive patch test reactions to common paint preservatives (ITs), and they report adult‐onset eczema more often than do less occupationally exposed groups.
The beneficial effects of neutrophil elastase inhibitor on gastrointestinal dysfunction in sepsis
Authors: Sun Jia‐Kui , Li Jing‐Jing , Deng Yi‐Hang , Yin Xiang , Huangfu Xiao‐Tian , Ye Zi‐Yu , Zhou Xue‐Hui , Chen Yong‐Ming , Yuan Shou‐Tao , Wang Xiang 
Published: May 2024

AbstractTo investigate the effects of neutrophil elastase inhibitor (sivelestat sodium) on gastrointestinal function in sepsis. A reanalysis of the data from previous clinical trials conducted at our center was performed. Septic patients were divided into either the sivelestat group or the non‐sivelestat group. The gastrointestinal dysfunction score (GIDS), feeding intolerance (FI) incidence, serum levels of intestinal barrier function and inflammatory biomarkers were recorded. The clinical severity and outcome variables were also documented. A total of 163 septic patients were included. The proportion of patients with GIDS ≥2 in the sivelestat group was reduced relative to that in the non‐sivelestat group (9.6% vs. 22.5%, p = 0.047) on the 7th day of intensive care unit (ICU) admission. The FI incidence was also remarkably reduced in the sivelestat group in contrast to that in the non‐sivelestat group (21.2% vs. 37.8%, p = 0.034). Furthermore, the sivelestat group had fewer days of FI [4 (3, 4) vs. 5 (4–6), p = 0.008]. The serum levels of d‐lactate (p = 0.033), intestinal fatty acid‐binding protein (p = 0.005), interleukin‐6 (p = 0.001), white blood cells (p = 0.007), C‐reactive protein (p = 0.001), and procalcitonin (p < 0.001) of the sivelestat group were lower than those of the non‐sivelestat group. The sivelestat group also demonstrated longer ICU‐free days [18 (0–22) vs. 13 (0–17), p = 0.004] and ventilator‐free days [22 (1–24) vs. 16 (1–19), p = 0.002] compared with the non‐sivelestat group. In conclusion, sivelestat sodium administration appears to improve gastrointestinal dysfunction, mitigate dysregulated inflammation, and reduce disease severity in septic patients.
Cytophagic histiocytic panniculitis leading to a diagnosis of acute myeloid leukemia with monocytic differentiation: A case report and literature review
Authors: Arnoff Taylor E. , Mirza Fatima N. , Yumeen Sara , Ben Khadra Shaza , George Dean David , Robinson‐Bostom Leslie 
Published: May 2024

AbstractCytophagic histiocytic panniculitis (CHP) is associated with a number of systemic conditions and is characterized by the presence of benign phagocytic histiocytes (“bean bag cells”), including phagocytosed erythrocytes, leukocytes, and platelets. We describe a case of a 72‐year‐old female who presented with a papular eruption that clinically mimicked pityriasis lichenoides et varioliformis acuta (PLEVA). Given that her skin biopsy had multiple features concerning PLEVA, this diagnosis was classified as a superficial pityriasis lichenoides‐like variant of CHP. The histopathologic presence of cytophagic histiocytosis prompted workup for a systemic malignancy, leading to a diagnosis of underlying acute monocytic leukemia of myeloid lineage.
Diagnostic delay in Hidradenitis suppurativa investigated using data from social media and from statutory health insurances
Authors: Kirschner Uwe , Kahn Maria , Papukchieva Steffeni , Stosio Karolina , Keis Andreas , Biermann Mona H. C. , Häusser‐Fruh Gisela , Sturm Lisa , Eberl Markus , Friedrich Benjamin , Kurzen Hjalmar 
Published: May 2024

SUMMARYBackgroundThe chronic inflammatory skin disease hidradenitis suppurativa (HS) leads to severe pain and reduced quality of life. Nonetheless, it often takes years until a correct diagnosis is made. In this analysis, disease‐related experiences and pathways of patients with HS were investigated and compared with the physicians’ perspective.MethodsPublic posts on forums and social media as well as results of a survey conducted among dermatologists and their patients on the actual medical care reality of HS in Germany were analysed. Furthermore, claims data from German health insurance companies were evaluated.ResultsPatients with HS suffer from a 43.3% reduction in working ability. Dermatology (26.5%) was the most frequently consulted specialty, with HS diagnosed predominantly in the inpatient setting (43.8%). Abscesses were described as the most frequent alternative diagnosis in HS patients (53.2%). Patient‐reported changes of physicians in dermatology (34.1%) and surgery (42.4%) occurred predominantly within the specialty. Dermatology received most referrals from general practitioners (67.1%), but only 12.1% from surgeons.ConclusionThere is an urgent need to reduce the delay in diagnosis and the prolonged burden of disease in patients with HS. Therefore, awareness of the disease, its detection and treatment which goes beyond dermatology should be promoted, if possible as part of medical studies.
Participatory translation and anti‐racism in NGO development work: A method of co‐producing translations with community members
Authors: Chasukwa Michael , Crack Angela 
Published: May 2024

AbstractMotivationThis article argues that the NGO sector should prioritize translation as an anti‐racist practice because failing to tackle colonial language hierarchies replicates historic power structures. Aligned with the locally led approach to development, the article responds to calls for more research into the role of translation in shaping development outcomes, and answers direct appeals from NGO practitioners for translation glossaries in different languages to improve communication between development actors.PurposeWe introduce a new participatory method for co‐producing translations of terms that community members deem important for their visions of “development” and social change. We contend that participatory translation fosters an anti‐racist approach to knowledge production by centring communities in the construction of meaning, which may encompass language and concepts outside the international development lexicon.Approach and methodsThe study was based on the principles of community‐based participatory research, and an Advisory Board of community members was instrumental in its design. The draft of the glossary was produced in two three‐day participatory workshops in Lilongwe and Zomba, Malawi. These were attended by 36 people representing potential user groups of the glossary.FindingsThe workshop participants created 385 translations of development terms, including 70 translations that are not listed in the Oxford Chichewa–English Dictionary. They also engaged in critically reflective discussions that challenged dominant discourses of development. We argue that participatory translation is a tool to transcend the language barrier in a way that simultaneously subverts conventional power hierarchies and offers access to different ways of understanding the world.Policy implicationsNGOs in different linguistic and geographical contexts could adopt participatory translation activities in the early stages of forming relationships with communities and local partners to build trust and common understanding. In line with an anti‐racist approach, this would help to combat systemic linguistic exclusion, which exacerbates other forms of disadvantage.
In vitro effects of wound‐dressings on key wound healing properties of dermal fibroblasts
Authors: Peltier S. , Adib Y. , Nicosia L. , Ly Ka So S. , Da Silva C. , Serror K. , Duciel L. , Proust R. , Mimoun M. , Bagot M. , Bensussan A. , des Courtils C. , Michel Laurence 
Published: May 2024

AbstractHealing of complex wounds requires dressings that must, at least, not hinder and should ideally promote the activity of key healing cells, in particular fibroblasts. This in vitro study assessed the effects of three wound‐dressings (a pure Ca2+ alginate: Algostéril®, a Ca2+ alginate + carboxymethylcellulose: Biatain alginate® and a polyacrylate impregnated with lipido‐colloid matrix: UrgoClean®) on dermal fibroblast activity. The results showed the pure calcium alginate to be non‐cytotoxic, whereas the other wound‐dressings showed moderate to strong cytotoxicity. The two alginates stimulated fibroblast migration and proliferation, whereas the polyacrylate altered migration and had no effect on proliferation. The pure Ca2+ alginate significantly increased the TGF‐β‐induced fibroblast activation, which is essential to healing. This activation was confirmed by a significant increase in Vascular endothelial growth factor (VEGF) secretion and a higher collagen production. The other dressings reduced these fibroblast activities. The pure Ca2+ alginate was also able to counteract the inhibitory effect of NK cell supernatants on fibroblast migration. These in vitro results demonstrate that tested wound‐dressings are not equivalent for fibroblast activation. Only Algostéril was found to promote all the fibroblast activities tested, which could contribute to its healing efficacy demonstrated in the clinic.
On the elastic–plastic behaviors of centrifugal steam compressor impeller under cyclic thermomechanical loading
Authors: Li Jianxun , Wang Xiaoxiao , Ma Zhiyuan , Lu Kai , Chen Haofeng , Wang Weiqiang 
Published: May 2024

AbstractIn this paper, the cyclic elastic–plastic behaviors of the centrifugal steam compressor impeller (CSCI) structure under practical operating conditions are discussed employing the linear matching method (LMM). The three‐stage strategy of the LMM is employed to determine the shakedown and ratchet boundaries by conducting a series of iterative direct steady cyclic analysis, and based on this, the load regions corresponding to different types of damage behavior that may occur during the operation are identified. Computational results reveal slight contraction in the structural response diagram when considering actual material constitutive relationships, compared to ideal elastic–plastic models. Meanwhile, by integrating the unified ratchet and fatigue program with fatigue experimental data, a series of constant low‐cycle fatigue life curves has been presented for different service conditions. Furthermore, a comparison with detailed step‐by‐step inelastic analyses confirms the applicability and great efficiency of the LMM in practical engineering problems.
Impact of persistently high sea surface temperatures on the rhizobiomes of Zostera marina in a Baltic Sea benthocosms
Authors: Aires Tânia , Cúcio Catarina , Brakel Janina , Weinberger Florian , Wahl Martin , Teles Ana , Muyzer Gerard , Engelen Aschwin H. 
Published: May 2024

AbstractPersistently high marine temperatures are escalating and threating marine biodiversity. The Baltic Sea, warming faster than other seas, is a good model to study the impact of increasing sea surface temperatures. Zostera marina, a key player in the Baltic ecosystem, faces susceptibility to disturbances, especially under chronic high temperatures. Despite the increasing number of studies on the impact of global warming on seagrasses, little attention has been paid to the role of the holobiont. Using an outdoor benthocosm to replicate near‐natural conditions, this study explores the repercussions of persistent warming on the microbiome of Z. marina and its implications for holobiont function. Results show that both seasonal warming and chronic warming, impact Z. marina roots and sediment microbiome. Compared with roots, sediments demonstrate higher diversity and stability throughout the study, but temperature effects manifest earlier in both compartments, possibly linked to premature Z. marina die‐offs under chronic warming. Shifts in microbial composition, such as an increase in organic matter‐degrading and sulfur‐related bacteria, accompany chronic warming. A higher ratio of sulfate‐reducing bacteria compared to sulfide oxidizers was found in the warming treatment which may result in the collapse of the seagrasses, due to toxic levels of sulfide. Differentiating predicted pathways for warmest temperatures were related to sulfur and nitrogen cycles, suggest an increase of the microbial metabolism, and possible seagrass protection strategies through the production of isoprene. These structural and compositional variations in the associated microbiome offer early insights into the ecological status of seagrasses. Certain taxa/genes/pathways may serve as markers for specific stresses. Monitoring programs should integrate this aspect to identify early indicators of seagrass health. Understanding microbiome changes under stress is crucial for the use of potential probiotic taxa to mitigate climate change effects. Broader‐scale examination of seagrass–microorganism interactions is needed to leverage knowledge on host–microbe interactions in seagrasses.
Early impacts of marginal land‐use transition toMiscanthuson soil quality and soil carbon storage across Europe
Authors: Bertola Marta , Magenau Elena , Martani Enrico , Kontek Mislav , Ashman Chris , Jurišić Vanja , Lamy Isabelle , Kam Jason , Fornasier Flavio , McCalmont Jon , Trindade Luisa M. , Amaducci Stefano , Clifton‐Brown John , Kiesel Andreas , Ferrarini Andrea 
Published: May 2024

AbstractMiscanthus, a C4perennial rhizomatous grass, is a low‐input energy crop suitable for marginal land, which cultivation can improve soil quality and promote soil organic carbon (SOC) sequestration. In this study, four promisingMiscanthushybrids were chosen to evaluate their short‐term potential, in six European marginal sites, to sequester SOC and improve physical, chemical, and biological soil quality in topsoil. Overall, no differences amongMiscanthushybrids were detected in terms of impacts on soil quality and SOC sequestration. SOC sequestration rate after 4 years was of +0.4 Mg C ha−1 year−1, but land‐use transition from former cropland or grassland showed contrasting SOC sequestration trajectories. In unfertilized marginal lands, cultivation of high‐yieldingMiscanthusgenotypes caused a depletion of K (−216 kg ha−1 year−1), followed by Ca (−56 kg ha−1 year−1), Mg (−102 kg ha−1 year−1) and to a lesser extent of N. On the contrary, the biological turnover of organic matter increased the available P content (+164 kg P2O5ha−1 year−1). SOC content was identified as the main driver of changes in biological soil quality. High input of labile plant C stimulated an increment of microbial biomass and enzymatic activity. Here, a novel approach was applied to estimate C input to soil from differentMiscanthusorgans. Despite the high estimated plant C input to soil (0.98 Mg C ha−1 year−1), with significant differences among sites andMiscanthushybrids, it was not identified as a driver of SOC sequestration. On the contrary, initial SOC and nutrients (N, P) content, as well as their elemental stoichiometric ratios with C, were the key factors controlling SOC dynamics. IntroducingMiscanthuson marginal lands impacts positively soil biological quality over the short term, but targeted fertilization plans are needed to secure crop yield over the long term as well as the C sink capacity of this perennial cropping system.