bluuebunny/crossref_metadata_2025_split huggingface dataset:
P03-371 - Electroconvulsive Therapy (ECT): a Retrospective Study of the Psychiatric unit of a Brazilian General Hospital from 1993 to 2007
Authors: Santos A. , Oliveira M.C. , Andrade T.S. , Freitas R.R. , Salán T.M. , Azevedo R.C.S. ,   ECT Study Group
Published: June 2010

ObjectivesTo describe the socio-demographic and clinical characteristics, complications and therapeutic response of patients treated with ECT in the Psychiatric Unit of the General Hospital from University of Campinas-Brazil (1993-2007).MethodsAll medical records of the patients who underwent ECT were reviewed and compiled for subsequent statistical analysis by SPSS program.Results156 patients were studied. Ages ranged from 13 to 78 years-old, with a mean of 39.9±17.8 years-old [95% CI: 37.2-42.8 years]. There were 64 (41%) men and 92 (59%) women. The main diagnostic categories of the patients submitted to ECT were: schizophrenia (33.9%), depression without psychotic symptoms (30.8%), depression with psychotic symptoms (39.1%), bipolar disorder (18.6%) and schizoaffective disorder (3.2%). Complications occurred during the procedure in 98 cases (62.8%), immediately after the application in 85 cases (54.5%) and three days after the last session in 33 cases (21.2%).The response to ECT was: good response in 132 (84.6%) patients, unchanged psychiatric symptoms in 14 (9%) patients and worsening in 3 (1.9%). The mean time of permanence inside the Psychiatric Unit was 57.5±38.2 days [95% CI: 51.4-63.2 days].Table1 1:Complications during the procedureComplicationsN%Incomplete seizure7950.6%Arrythmia3220.5%Prolonged seizure2214.1%Ineffective session after three applications2113.5%Hypertensive episode1811.5%Table 2:Complications immediately after the proceComplicationsN%Mental confusion3824.4%Amnesia2616.7%Headache2314.7%Gastrointestinal alterations1811.5%Pneumonia21.3%Pulmonary thromboembolism21.3%Manic turn21.3%Bronchospasm10.6%Subarachnoid hemorrhage10.6%Table 3:Complications at least three days after tComplicationsN%Amnesia1710.9%Mental confusion106.4%Headache63.8%ConclusionsThe diagnostic categories for which ECT therapy corresponded to those described in the literature. Data suggest that the incidence of complications was moderate and the response to treatment was positive in most cases, reinforcing the importance of this therapeutic method for the treatment of patients with severe mental illness.
P03-373 - Relation Between Symptomatic and Functional Outcomes in Adults with ADHD Treated with OROS MPH - a Partial Correlation Analysis
Authors: Buitelaar J.K. , Roesler M. , Kooij S. , Casas M. , Dejonckheere J. , van Oene J. , Schaeuble B. , Trott G.-E. 
Published: June 2010

ObjectiveTo explore the relationship between symptomatic and functional outcomes in a five week, double blind, fixed dose, placebo controlled study in adults (age 18-65 years) with ADHD.MethodsPost hoc-analysis of a five-week, double-blind (DB), parallel arm, placebo-controlled trial in adult subjects with ADHD (DSM-IV) and a Conners’ Adult ADHD Rating Scale (CAARS) score >= 24 at baseline. Subjects were randomized to OROS-MPH (18mg, 36mg, 72 mg/day) or placebo. Symptomatic outcomes were assessed by total CAARS score (TCS). Functional outcomes were assessed by Sheehan Disability Scale (SDS) total score and subscales (work, social life and family life), quality of life by Q-LES-Q total score. The relationship of CAARS with SDS and Q-LES-Q was assessed by Pearson's partial correlation analysis, with adjustment for baseline scores of CAARS, SDS, Q-LES-Q, CGI-S, age, sex, and randomization group.Results401 subjects were enrolled (54.4% male, mean (SD) age 34 (10.24) yrs). There was a significant treatment effect as measured in TCS at DB endpoint for all OROS MPH treatment groups compared to placebo (P< 0.05). The absolute value of partial correlations of symptomatic outcome with functional outcomes and quality of life varied between 0.54 and 0.36; all correlations were significant (p< 0.0001). These correlations were compared between the functional and quality of life measures, but none differed significantly.ConclusionSubjects’ symptomatic improvements during treatment with PR OROS MPH are reflected in improvements in their vocational and social function as measured by the SDS, and quality of life.
P03-379 - The use of Clozapine in Children and Adolescents with Serious Conduct Disorder for Control of the Aggressiveness
Authors: Teixeira E.H. , Santos A. , Salán T.M. , Jacintho A.C.d.Á. , Celeri E.H.R.V. , Dalgalarrondo P. ,   Child and Adolescent Psychiatry Study Group
Published: June 2010

ObjectivesTo analyze the use of Clozapine in six children and adolescents with Serious Conduct Disorder, whose symptoms had been refractory to other pharmacology treatment. Scalar analysis is supplied for the more important psychopathology aspects and the changes with therapeutic one.MethodsSix patients diagnosed with Serious Conduct Disorder are described who had begun the use of Clozapine. They had been widely studied and received application of standardized instruments of infantile psychiatry (CBCL - Child Behavior Check List) before and after the use of this medication.ResultsThe patients had mainly significant improvement in relation to the level of aggressiveness and social behavior.ConclusionsAlthough ample studies on the use of this medication in children and adolescents do not yet exist, more precisely for cases of Serious Conduct Disorder, the preliminary results are very positive and indicate that Clozapine could be an important tool in the handling of the aggressiveness in those refractory patients with Serious Conduct Disorder.
P03-385 - Aripiprazole in the Treatment of Risperidone Associated Tardive Dyskinesia
Authors: Yilmaz O. , Ates M.A. , Algul A. , Semiz U.B. , Basoglu C. , Ebrinc S. , Cetin M. 
Published: June 2010

ObjectivesTardive dyskinesia(TD) is a syndrome characterized by repetitive involuntary movements, usually involving mouth, face and tongue and sometimes the extremities. Atypical antipsychotics are of significantly lower risk for causing tardive dyskinesia, about one-fifth comparing with first generation antipsychotics. Furthermore, there is growing evidence that they may have a therapeutic effect on TD. We present a case that demonstrated a marked improvement in risperidone-induced TD following treatment with aripiprazole.MethodMr. A is a 21-year-old single male with a DSM-IV-TR diagnosis of schizophrenia, of approximately 2 years duration. He was mainly maintained on risperidone 4-6 mg/day during this time. Upon his admittance to our clinic, he was suffering auditory hallucinations, persecutory delusions, social withdrawal and he was noticed to have had some involuntary mouth movements. The patient scored three out of four (moderate) on the ‘lips and peri-oral area’ subcategory of the- Abnormal Involuntary Movement Scale (AIMS). A cranial CT scan was unremarkable and there was no past history or family history of neuro-psychiatric disorders. He was started on aripiprazole 15 miligrams per day.ResultsWithin two weeks a marked improvement was seen in his psychotic symptoms and he scored 2 on the AIMS. Two months after starting aripiprazole, he was free of psychotic symptoms and dyskinetic movements.ConclusionAltough atypical antipsychotics are known to be associated with lower risk of developing tardive dyskinesia, psychiatrists should be aware of these rare conditions. Aripiprazole, as a partial dopamine agonist, might be an alternate pharmacotherapy in threating psychosis and atypical antipsychotic-induced TD.
P02-298 - Clinical Course of Patients with Anorexia Nervosa in an In-Patient Adolescent Eating Disorder Unit
Authors: Clancy M. , Codd M. , McNamara D. 
Published: June 2010

IntroductionThis study examined adolescents with anorexia nervosa admitted to a tertiary referral unit in Dublin over a 3 year period.The aims of the study were to assess changes if any in patient clinical and laboratory parameters specifically weight change, body mass index (BMI), cardiovascular, haematological and biochemical measurements over the course of in-patient stay.MethodsHospital computerized databases and clinical case notes were examined for each patient.Results were compared with Royal College of Psychiatrists (RCP) and National Institute for Clinical Evidence (NICE) guidelines for treatment of in-patients with anorexia nervosa.ResultsThere were at total of 42 admissions over the 3 years.7 males and 35 females were admitted.Median length of admission was 88 days. Female patients gained on average 7.2 kilograms during their admission.The average female BMI on admission was 14.9 on admission and 17.6 on discharge. 82.3% of female admissions had blood abnormalities, the most common being anaemia and hypokalaemia.45.7% of female patients had an abnormal electrocariograph.25% of female patients required transfer out during their admission for medical review.ConclusionThe eating disorder unit fulfilled the RCP and NICE guidelines for 97.6% of patients in terms of blood results performed and 92.8% in terms of electrocardiographs performed.The average BMI on discharge for both males and females was above 17.5 which is regarded as the normal cut off point for anorexia nervosa.The importance of this study despite its limited sample size is that it is the first study of investigations and outcomes in an Irish in-patient adolescent eating disorder sample.
P02-304 - Alexithymia is Associated with Eating Disorder Symptoms in Adolescents
Authors: Karukivi M. , Hautala L. , Korpelainen J. , Haapasalo-Pesu K.-M. , Liuksila P.-R. , Joukamaa M. , Saarijärvi S. 
Published: June 2010

ObjectivesIncreasing amount of evidence indicates an association between alexithymia and eating disorder (ED) symptoms. The aim of this study was to evaluate possible association between alexithymia and EDs in a non-clinical sample of late adolescents.MethodsThe questionnaire was sent to 935 adolescents of whom 729 (78%) completed it, thus forming the final sample. The mean age in the sample was 19 years (range 17−21 years). Alexithymia was measured using the 20-item Toronto Alexithymia Scale (TAS-20) and ED symptoms were assessed using the SCOFF questionnaire, a novel tool for screening ED symptoms. A TAS-20 score of 61 or more was used as the cut-off point for classifying a subject as alexithymic, and for SCOFF, the cut-off point for a SCOFF positive subject was of two or more positive answers.ResultsThe rate of alexithymia was 8.2% (8.2% for females and 8.5% for males). The mean TAS-20 scores were 44.65 for females and 45.98 for males without any gender difference. Among the alexithymic adolescents, the share of SCOFF positive subjects was significantly higher as compared to the non-alexithymic group (32.2% vs. 11.3%). The mean SCOFF scores also differed significantly between alexithymic and non-alexithymic subjects (0.93 vs. 0.42). The association was clear in the DIF and DDF subscales of TAS-20.ConclusionsThe results suggest that ED symptoms are more common in alexithymic adolescents. However, the evaluation of causal links calls for longitudinal studies.
P02-306 - Eating Disorders - Types of Obsessive-Compulsive Disorder a Case Display
Authors: Krasic D. 
Published: June 2010

Both anorexia mentalis and bulimia nervosa are types of eating disorder (F 50.)Anorexia is a disorder characterized by deliberate loss of body weight.Bulimia is a disorder featured by repeated attacks of excessive eating as well as preoccupation with body weight. Obsessive-compulsive disorder is qualified by recurrent obsessive thoughts and/or actions which repeatedly appear in ones’ mind.A display of a 25 year old female with an eating disorder and obsessive-compulsive disorder conjoint on the basis of an anancastic personality, followed by combination of pharmacotherapeutic and psychotherapeutic treatment.Psychiatric interview, psychological tests (personality test, IQ evaluation test), psychiatric treatment (individual psychodynamic therapy, family therapy; support therapy.) At the beginning of the treatment, the patient had low body weigh (BMI 18), was depressed and dysfunctional, further to occasional bulimic behavior and obsessive-compulsive behavior. Previously she had been treated with antidepressants and basal neuroleptics, clinically and in a dispensary, for a year. After successfully creating a contact and forming a therapeutic alliance, she was submitted to an individual psychiatric treatment as well as family therapy. In addition, pharmacotherapy, which included small doses of atypical neuroleptic and a tricyclic antidepressant, was introduced.During the first two months of treatment, the subject's body weight increased (BMI 18), symptoms of obsessive-compulsive disorder disappeared, depressive symptoms reduced, and functionality restored. The patient is still being psychiatrically treated.Different types of obsessive-compulsive disorder may be developed in an anancastic personality at the same time. However, this does not obstruct psychotherapeutic nor pharmacotherapeutic treatment.
P02-309 - Functional Relaxation in Psychosomatic Medicine - Results From Randomized-Controlled Trials
Authors: Lahmann C. , Henningsen P. , Loew T. 
Published: June 2010

Functional relaxation is a somatopsychotherapeutic intervention technique commonly used in Germany, Austria and Switzerland for the treatment of psychosomatic disorders. The therapeutic effects are assumed to be delivered by positive stimulation of the autonomic nervous system, as well as by facilitation of proprioreceptive awareness. Minute movements of small joints, hardly noticeable to observers, are performed during relaxed expiration, accompanied by a focus on and exploration of the perceived differences of bodily feelings triggered by these movements. Unlike exercise-based methods, such as progressive muscle relaxation, the bodily perceptions are explicitly verbalized and processed in the therapeutic relationship.By now, a number of randomized controlled studies have proven the effectiveness of Functional Relaxation in various disorders such as tension headache, bronchial asthma, irritable bowel syndrome, non-specific-chest pain and dental anxiety.
P02-311 - The questionnaire of Eating Behaviours: Creating and Validating a New Screening Instrument For Eating Disorders
Authors: Focà F. , Luci G. , D’Alessandris L. , Blanco P. , Del Basso G. , Vasale M. 
Published: June 2010

ObjectivesEating Disorders concern a growing number of people. Several instruments were created to assess symptomatology of Anorexia Nervosa and Bulimia Nervosa. Our aim is to create and validate a short questionnaire about all the eating symptoms of Eating Disorders, including Binge Eating Disorder.MethodsThe Questionnaire of Eating Behaviours (Scheda dei Comportamenti Alimentari, SCA) is a self-administered questionnaire composed of 13 items regarding all the eating symptoms of Eating Disorders. Items are divided into 3 scales: Restrictive Eating, Weight Control Practices and Binge Eating. The SCA was given to 200 female outpatients with Eating Disorders and to 218 non-clinical adult women. Student's t test was performed to compare clinical and non-clinical subjects, one-way ANOVA was performed to compare three diagnostic subtypes (Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder). Cronbach's Alpha and factor analysis were used to validate the questionnaire.ResultsClinical and non-clinical subjects get significantly different scores in all the three subscales. Besides, the three diagnostic subtypes scores significantly differ on each scale. Cronbach's Alpha values show a significant inner consistency in the subscales of Restrictive Eating and Binge Eating, while the Weight Control Practices one is not very homogeneous, as expected. The factor analysis has shown the presence of three factors, corresponding to the 3 scales.ConclusionsThe SCA has shown to be effective in distinguishing people with Eating Disorders from non-clinical subjects. For its characteristics of being short, easy to fill in and to interpret, the SCA seems to be an instrument suitable for screening purposes.
P02-319 - Development and Evaluation of Aplicability for A Psychoeducative Manual As First Intervention on the Treatment of Binge Eating Disorder
Authors: Stefano S. , Devoraes A.M. , Blay S. 
Published: June 2010

ObjectiveThe objective of this Project was to develop and evaluate the applicability of a psychoeducative manual adapted to the Brazilian population reality, as first intervention on the treatment of BED patients.MethodThe manual is printed in a brochure format, using a non-medic language, where the information is presented with images and fictitious characters, allowing patients to make use of it without supervision of a specialized professional.The first part gives information about the disease, characteristics and symptoms, allowing the patient to identify if he has or not the disorder, partial or complete.The second part gives the mechanisms that predispose, start and perpetuate the eating disorder, helping the patient to recognize them and develop strategies to modify his behavior.ResultsSeveral versions have been improved by the authors; when a definitive format was achieved, the manual was evaluated by eight eating disorders specialized professionals, who presented their comments and suggestions on the format and contents. After implemented the changes, the 12th version was settled as final, consisting of 10 items. Then, this manual was submitted to 10 patients, to be evaluated regarding information assimilation through a questionnaire specially developed for this purpose.ConclusionsThis is the first psychoeducative manual for BED patients in Brazil. Its final version was considered by the patients a quick and easy to understand reading. Due to the low range of specialized professional assistance, such manual can be very relevant. Studies to evaluate the efficaciousness of this manual are currently under process.
P02-321 - Chronic Fatigue Syndrome: Novel Treatment Perspectives
Authors: Stubhaug B. ,   Frihamnsenteret Clinical Research Center of Psychological Medicine
Published: June 2010

Chronic Fatigue Syndrome (CFS) often presents with severe subjective symptoms and may be accompanied by severe global impairment. No specific treatment has yet been proven to be universally effective; CBT and graded exercise has so far lead to moderately positive results. We present a treatment model based on a comprehensive, educational, cognitive-oriented and mindfulnes-based intervention program, where illness perception and illness behaviour are being challenged. Knowledge of the illness, a comprehensible illness model and understanding unexplainable symptoms constitute the education program. Mindfulness training and stress reduction, combined with cognitive group therapy are essential part of the program. Knowledge, thoughts and feelings are being adressed, including the experience of life satisfaction and positive and negative emotions.We present data on stress parameters, mindfulness items and lifte satisfaction factors, pre and post treatment.
P02-327 - Persistence and Reversibility of Neuroimaging Alterations in Anorexia Nervosa Patients After Weight Recovery: A Review of Literature Studies
Authors: Meuti V. , Loriedo C. , Costa E. 
Published: June 2010

IntroductionAnorexia nervosa (AN) is a chronic and relapsing disorder, characterized by aberrant patterns of weight regulation and eating behaviour, body image distortion and resistance to treatment.AimsThis study aims to investigate the reversibility of the most important structural and functional cerebral alteration found in the illness state after weight recovery, in order to distinguish between state-dependent abnormalities and neurological signs of traits vulnerability.MethodsThe most significant neuroimaging studies are reviewed from the scientific literature of the last ten years, using the following keywords: “neuroimaging”, “anorexia”, “reversibility”, “weight recovery”, “cerebral blood flow”, differently matched together.ResultsStructural neuroimaging techniques show a widening of internal cerebrospinal fluid filled spaces and a brain gray and white matter volume loss. These alterations take place in the low-stages of AN, as body weight decreases, and generally reverse with weight restoration, as a function of re-feeding. Functional neuroimaging studies reveal a reduced global and regional cerebral glucose metabolism in the acute state, that reverses with recovery. On the other hands, techniques based on stimuli provocation reveal a greater activation in the medial prefrontal and anterior cingulate cortices in response to food stimuli, that persists after recovery, suggesting that these alterations could be primary abnormalities related to trait vulnerability.ConclusionsOther studies needs to distinguish between primary neural disturbance and secondary phenomena due to starvation, in order to individuate patterns of vulnerability and to develop new strategies of treatment and prevention.
P02-339 - Internet-Based Therapy Process Monitoring of Psychotherapy Using the Synergetic Navigation System (SNS) -Methodology and Case Report
Authors: Dold M. , Demal U. , Lenz G. , Schiepek G. , Aigner M. 
Published: June 2010

IntroductionTo improve the quality of psychotherapy, computer-assisted feedback and monitoring systems to evaluate continuously an ongoing course of therapy have gained increased importance in psychotherapy research. They can provide both therapists and the patients themselves with feedback about the progress of the treatment to date while psychotherapy is still taking place. The information gained from them can be used to match the treatment better to patients’ individual needs.MethodThis work presents an Internet-based real-time monitoring method, the Synergetic Navigation System (SNS). This is based on a daily self-assessment by the patient, and is thus characterized by recording the therapy process at particularly narrow time intervals. The technology is illustrated by means of a single case example of a patient with obsessive-compulsive disorder who took part in a two-month inpatient behavioural therapy.ResultsIt can be shown that SNS time-series analysis enables the whole course of therapy to be depicted well, without any serious time delay, and it is possible to record phases in which therapeutic interventions are particularly effective (phases of critical instability).DiscussionOn the one hand monitoring a psychotherapy is useful for psychotherapy research because it enables the dynamics of the therapy progress to be investigated better and it is possible to identify exactly which therapeutic intervention at which time produces what effect on the patient. On the other hand it is useful for the psychotherapist who is working mainly clinically, because the regular feedback enables him to match his therapy to the patient's specific needs.