bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case study analysis of a successful birth center in northern Uganda
Authors: Telfer Michelle , Zaslow Rachel , Nalugo Mbalinda Scovia , Blatt Rachel , Kim Diane , Kennedy Holly Powell 
Published: June 2024

AbstractBackgroundMothers and infants continue to die at alarming rates throughout the Global South. Evidence suggests that high‐quality midwifery care significantly reduces preventable maternal and neonatal morbidity and mortality. This paper uses a case study approach to describe the social and institutional model at one birth center in Northern Uganda where, in over 20,000 births, there have been no maternal deaths and the neonatal mortality rate is 11/1000—a rate that is lower than many high‐resource countries.MethodsThis case study combined institutional ethnographic and narrative methods to explore key maternal and neonatal outcomes. The sample included birthing people who intended to or had given birth at the center, as well as the midwives, staff, stakeholders, and community health workers affiliated with the center. Data were collected through individual and small group interviews, participant observation, field notes, data and document reviews. Iterative and systematic analytical steps were followed, and all data were organized and managed with Atlas.ti software.ResultsFindings describe the setting, an overview of the birth center's history, how it is situated within the community, its staffing, administration, clinical outcomes, and model of care. A synthesis of contextual variables and key outcomes as they relate to the components of the evidence‐informed Quality Maternal and Newborn Care (QMNC) framework are presented. Three overarching themes were identified: (a) community knowledge and understanding, (b) community integrated care, and (c) quality care that is respectful, accessible, and available.ConclusionsThis birth center is an example of care that embodies the findings and anticipated outcomes described in the QMNC framework. Replication of this model in other childbearing settings may help alleviate unnecessary perinatal morbidity and mortality.
Seabird presence and seasonality influence nutrient dynamics of atoll habitats
Authors: Appoo Jennifer , Bunbury Nancy , Letori Jake , Hector Aurelie , Gendron Annie , Graham Nicholas A. J. , Rocamora Gerard , Le Corre Matthieu , Jaquemet Sébastien 
Published: June 2024

AbstractMarine nutrients underpin productivity and functioning of oceanic island ecosystems. On islands where they nest, seabirds represent a primary source of marine nutrients. In tropical regions, some of the largest seabird populations nest on atolls, yet there is limited information available on seabird contributions to atoll ecosystem nutrient dynamics. To investigate the spatial and seasonal dynamics of seabird contributions, we assessed seabird colonies of different taxa, including red‐footed boobies and terns, nesting on separate islands of Farquhar Atoll, Seychelles. We assessed nutrient concentrations of guano, soil, coastal plants, and nearby seagrass in seabird colonies and at a control island with no seabirds, during the wet and dry seasons. Sooty terns contributed the highest quantities of nutrients, estimated at 71.2 N tonne/year and 52.2 P tonne/year. Seabird‐derived nutrient transfer occurred year‐round from seabird colonies to soil, coastal plants and seagrass. Soil macro‐ and inorganic nutrients were higher in the high‐density tern colony and during the dry season, coinciding with the breeding period of sooty terns. Both red‐footed booby and tern colonies maintained high nitrogen levels in coastal plants year‐round, while phosphorus levels did not differ between islands or seasons. Seabird‐derived nitrogen reversed nitrogen limitation of seagrass during the dry season. We provide the first insights into seabird nutrient contributions to atoll ecosystems in Seychelles, with recommendations for seabird conservation to boost and support atoll and island ecosystem resilience. Our results from a relatively undisturbed atoll serve as a baseline with which more impacted atolls and future changes can be assessed.
Randomized split‐mouth clinical trial comparing osteoblastic activity and osteogenic potential of autogenous particle harvesting during implant surgery without irrigation and with irrigation
Authors: Camacho‐Alonso Fabio , Mercado‐Díaz Ana María , Rivas‐Ballester Rebeca , Bernabeu‐Mira Juan Carlos , Peñarrocha‐Oltra David , del Rosario Tudela‐Mulero María 
Published: June 2024

AbstractObjectiveTo compare the osteoblastic activity and osteogenic potential of autogenous particle harvesting during implant surgery using low‐speed drilling without irrigation and high‐speed drilling with irrigation.Materials and MethodsThirty patients with bilateral missing teeth of 3.6 and 4.6 were randomized into two groups (Group 1: low‐speed drilling without irrigation and Group 2: high‐speed drilling with irrigation) and 60 single dental implants were placed. The temperature at the tip of each drill was recorded and the harvested bone was weighed; particle size and Ca and P levels were also analyzed. After osteoblast culture, cell viability, cell cycle assay, cell migration, vascular endothelial growth factor (VEGF) concentration, and mineralized nodule formation were assessed.ResultsAlthough the temperature of the drills was slightly higher in Group 1, no statistically significant differences were observed (p ≤ 0.05); however, the amount of harvested bone was higher (p < 0.001) and the size of the particles was higher (p = 0.019). In relation to osteoblastic activity and osteogenic potential, higher cell proliferation, higher number of cells in G2/M and S phases, higher cell migration capacity, higher VEGF concentration, and higher amount of mineralized nodule formation were observed in Group 1.ConclusionsLow‐speed drilling without irrigation does not result in a significant increase in bone temperature compared to conventional drilling. However, a greater amount of bone is obtained; in addition, osteoblastic activity and osteogenic potential are higher with this technique, but further clinical studies are necessary.
Economic voting behavior: The peak‐end growth rule
Authors: Shen Zekai , Jin Yiyang , Dong Yuanyuan , Liu Yazhou 
Published: June 2024

AbstractThis paper introduces the peak‐end rule to economic voting, finding that voters focus on peak and end economic growth when evaluating incumbents. Cross‐national data from 595 elections in 70 countries (1960–2020) shows that the average of the highest GDP growth rate during the term and the growth rate in the election year positively impacts incumbent vote share, with peak growth having a stronger effect. Instrumental variable analysis addresses endogeneity. Heterogeneity analysis reveals that less‐educated voters rely more on the peak‐end rule. The findings contribute to understanding voters' behavioral patterns and improving democratic accountability.
Anomalies, option volume, and disagreement
Authors: Hameed Allaudeen , Jeon Byounghyun (BH) 
Published: June 2024

AbstractWe document robust amplification of stock market anomaly returns associated with elevated option trading volume driven by disagreement trades. Consistent with the correction of mispricing associated with biased beliefs, anomaly returns are higher when disagreement option volume is high prior to earnings announcements. Additionally, we demonstrate that disagreement‐based option volume is negatively related to future stock returns among stocks that are overpriced based on anomaly characteristics. Our findings also concentrate in stocks that are also difficult to short, emphasizing the combined impact of investor bias and shorting costs. Leveraging the staggered adoption of eXtensible Business Reporting Language, we establish a plausibly identified link between investor disagreement and short‐horizon mispricing in stocks.
Application of vacuum‐sealing drainage in buttonhole‐related arteriovenous fistula infection: A case report
Authors: Luo Manyu , Ding Yushuang , Qu Zhijie , Feng Wenyuan , Lu Xuehong 
Published: June 2024

AbstractFew studies have reported the application of vacuum‐sealing drainage of infected dialysis vascular access wounds. Herein, we present a case of buttonhole‐related arteriovenous fistula infection treated with vacuum‐sealing drainage. A 53‐year‐old female hemodialysis patient was hospitalized with an inflamed arteriovenous fistula. The patient underwent non‐tunneled catheterization for dialysis and was treated with moxifloxacin and vancomycin for staphylococcal infection. On Day 3, the skin overlying the inflamed fistula was ulcerated, resulting in severe hemorrhage. Emergency surgery was performed along with vacuum‐sealing drainage for fistula reconstruction. Vacuum‐sealing drainage accelerated the recovery of the wound without complications. No further access complications occurred during over a 3‐year follow‐up.
Circadian functional changes of pain‐processing brainstem nuclei and implications for cluster headache: A 7 Tesla imaging study
Authors: Pohl Heiko , Neumeier Maria S. , Gantenbein Andreas R. , Wegener Susanne , Rosio Michael , Hennel Franciszek , Sandor Peter S. , Weller Michael , Michels Lars 
Published: June 2024

AbstractBackgroundPain thresholds and primary headaches, including cluster headache attacks, have circadian rhythmicity. Thus, they might share a common neuronal mechanism.ObjectiveThis study aimed to elucidate how the modulation of nociceptive input in the brainstem changes from noon to midnight. Insights into the mechanism of these fluctuations could allow for new hypotheses about the pathophysiology of cluster headache.MethodsThis repeated measure observational study was conducted at the University Hospital Zurich from December 2019 to November 2022. Healthy adults between 18 and 85 years of age were eligible. All participants were examined at noon and midnight. We tested the pain threshold on both sides of the foreheads with quantitative sensory testing, assessed tiredness levels, and obtained high‐field (7 Tesla) and high‐resolution functional magnetic resonance imaging (MRI) at each visit.Functional connectivity was assessed at the two visits by performing a region‐of‐interest analysis. We defined nuclei in the brainstem implicated in processing nociceptive input as well as the thalamus and suprachiasmatic nucleus as the region‐of‐interest.ResultsTen people were enrolled, and seven participants were included. First, we did not find statistically significant differences between noon and midnight of A‐delta‐mediated pain thresholds (median mechanical pain threshold at noon: left 9.2, right 9.2; at night: left 6.5, right 6.1). Second, after correction for a false discovery rate, we found changes in the mechanical pain sensitivity to have a statistically significant effect on changes in the functional connectivity between the left parabrachial nucleus and the suprachiasmatic nucleus (T = −40.79).ConclusionThe MRI data analysis suggested that brain stem nuclei and the hypothalamus modulate A‐delta‐mediated pain perception; however, these changes in pain perception did not lead to statistically significantly differing pain thresholds between noon and midnight. Hence, our findings shed doubt on our hypothesis that the physiologic circadian rhythmicity of pain thresholds could drive the circadian rhythmicity of cluster headache attacks.
Differences in circulating alpha‐calcitonin gene–related peptide levels in inflammatory bowel disease and its relation to migraine comorbidity: A cross‐sectional study
Authors: Pascual‐Mato Marta , Gárate Gabriel , González‐Quintanilla Vicente , Madera‐Fernández Jorge , Castro Beatriz , García María José , Crespo Javier , Rivero Montserrat , Pascual Julio 
Published: June 2024

AbstractObjectiveTo analyze the specificity of calcitonin gene–related peptide (CGRP) levels, we measured alpha‐CGRP circulating levels in a large series of patients with a recent diagnosis of inflammatory bowel disease (IBD) who were interviewed regarding comorbid headache.BackgroundSeveral studies have found an association between migraine and IBD.MethodsIn this cross‐sectional study performed in an IBD clinic, morning serum alpha‐CGRP levels were measured by enzyme‐linked immunosorbent assay in 96 patients who were recently diagnosed with IBD and compared to those from 50 similar patients with chronic migraine (CM) and 50 healthy controls (HC).ResultsAlpha‐CGRP levels were higher in patients with IBD (median [interquartile range] 56.9 [35.6–73.9] pg/mL) and patients with CM (53.0 [36.7–73.9] pg/mL) compared to HC (37.2 [30.0–51.8] pg/mL; p = 0.003; p = 0.019, respectively). Regarding IBD diagnostic subtypes, alpha‐CGRP levels for ulcerative colitis (67.2 ± 49.3 pg/mL; 57.0 [35.6–73.4] pg/mL) and Crohn's disease (54.9 ± 27.5 pg/mL; 57.7 [29.1–76.1] pg/mL) were significantly higher than those of HC (p = 0.013, p = 0.040, respectively). Alpha‐CGRP levels were further different in patients with IBD with migraine (70.9 [51.8–88.7] pg/mL) compared to HC (p < 0.001), patients with IBD without headache (57.5 [33.3–73.8] pg/mL; p = 0.049), and patients with IBD with tension‐type headache but without migraine (41.7 [28.5–66.9] pg/mL; p = 0.004), though alpha‐CGRP levels in patients with IBD without migraine (53.7 [32.9–73.5] pg/mL) remained different over HC (p = 0.028).ConclusionTogether with CM, circulating alpha‐CGRP levels are different in patients with IBD, perhaps reflecting a chronic inflammatory state. IBD is an example of how alpha‐CGRP levels are not a totally specific migraine biomarker. However, alpha‐CGRP levels were further increased in patients with IBD who have a history of migraine, which reinforces its role as a biomarker in migraine patients, always bearing in mind their comorbidities.
Defining a learning curve for urology trainees to achieve renal access without complications in endoscopic combined intrarenal surgery
Authors: Yanase Takahiro , Taguchi Kazumi , Sugino Teruaki , Sue Yasuhito , Isogai Masahiko , Hattori Tatsuya , Chaya Ryosuke , Okada Tomoki , Kawase Kengo , Unno Rei , Hashimoto Hiroya , Hamamoto Shuzo , Ando Ryosuke , Okada Atsushi , Yasui Takahiro 
Published: June 2024

ObjectivesThere is a lack of data on the number of surgeries required for endoscopic combined intrarenal surgery (ECIRS). Accordingly, we aimed to identify the learning curve for ECIRS performed by multiple surgeons.MethodsWe included 296 patients who underwent ECIRS at our university hospital between 2016 and 2021. A learning curve for percutaneous nephrolithotomy side was calculated considering urology‐resident surgeons. The learning curve was retrospectively analyzed for surgical time, renal puncture time, stone‐free rate, and complications and corrected for age, body mass index, stone size, computed tomography value, cumulative number of surgeries, and stone location.ResultsThis study included cases performed by 32 surgeons, including 30 residents and 2 attending surgeons. The median number of surgeries performed by the residents and attending surgeons prior to this study was 4.5 and 90, respectively. The median number of surgical procedures performed during the training period was seven. The surgical time of the residents decreased as the number of cases increased, reaching a median surgical time of 111 min for the attending surgeons after 16.4 cases. Renal puncture time was achieved in 20.1 cases. Complications related to renal access were observed in 13.0% (34 patients), Clavien–Dindo grade II in 1.9% (5 patients), and grade III or higher in 0.8% (2 patients). Comparing the first to fifth cases with the 21st and subsequent cases, the complication rate improved from 35% to 13%.ConclusionOur study demonstrated that ECIRS training provided 16–20 cases with a learning curve to achieve acceptable surgical outcomes.
Determinants of Water Source Choice for Irrigation in the Arkansas Delta
Authors: Kovacs Kent , Henry Christopher , Huang Qiuqiong , Krutz Larry Jason 
Published: June 2024

AbstractThe use and the share of water applied from several irrigation water sources correlate with the irrigation practices in use by the peers of Arkansan farmers. From a sample of producers from an irrigation survey in Arkansas, a bivariate sample selection model accounts for how peer use of numerous irrigation practices affects the use and the share of irrigation that comes from a water source. The bivariate sample selection model controls for the bias in the statistical estimates that occur because producers who volunteer for an irrigation survey are likely to know about and use irrigation more than the population. We find that peer influence operates through multiple irrigation practices, and peer influence through an irrigation practice depends on an irrigator's location and current farm practices. For example, peer use of a tail‐water recovery system and peer use of alternate wetting and drying both increase the probability of surface water use alone.
Feasibility of Wastewater‐based Public Health Monitoring Systems in Texas’ Small Rural Communities
Authors: Mendoza‐Sanchez Itza , Smyth Davida S. , Mendez Monica O. , Pearl Trish , Rifai Hanadi , Howell Nathan , Butler Erick 
Published: June 2024

AbstractIn recent years, there has been much focus on the use of wastewater‐based epidemiology (WBE) in urban centers, particularly for SARS‐CoV‐2 monitoring. However, less is known about the application of WBE in rural settings or in areas of limited resources. Most WBE programs in low‐resource communities have occurred outside the United States. To reap the benefits, WBE would need to be tailored to better reflect the socioeconomic challenges, technical barriers, communication limitations, and variable wastewater infrastructures associated with rural communities. The objective of this review is to evaluate the potential opportunities and challenges of deploying the current SARS‐CoV‐2 monitoring methodologies in small, rural communities, with a particular focus on rural Texas. For this, we conducted an inventory of rural communities in the state of Texas and their wastewater infrastructure. Based on specific rural examples, we evaluated the potential of current WBE methodologies used in urban settings to monitor for emerging biological agents of concern such as SARS‐CoV‐2. Our findings include an overview of rural wastewater capacity across rural Texas, a look at current WBE efforts to detect SARS‐CoV‐2, and recommendations for future implementation in two cities in rural counties, Kerrville and Valentine. WBE is a rapidly evolving public health tool with several notable advantages associated with cost, access, and adaptability. It is of particular use in resource‐limited communities that often exhibit healthcare disparities. This study presents the first overview of the feasibility of implementing WBE in the rural settings of Texas. We provide several recommendations and suggest alternatives that may be of use when planning an expansion of WBE into these areas.
Perfect couple or toxic relationship? A meta‐analysis of the effects and interplays of lean and agile strategies to improve performance
Authors: Matz Katharina , Foerstl Kai , Suurmond Robert 
Published: June 2024

AbstractBoth lean and agile practices have emerged as dominant organizational strategies to improve supply chain and firm performance. In addition, combinations of lean and agile, so‐called leagile practices, have developed. Most extant studies have tested the effects of specific subsets of lean, agile, or leagile practices on performance. This study proposes a comprehensive framework to investigate the complementary versus mutually exclusive performance gains of lean, agile, and leagile practices and their combinations. We review the literature and conduct a meta‐analysis of 127 empirical studies, yielding a total of 969 effect sizes across 30,741 firms. Our results indicate support for the positive link between lean, leagile, and agile practices and firm performance. Further analyses provide support for some aspects of cumulative capability theory, while others support aspects of trade‐off theory. We thereby enlighten the discourse about the cumulative and comparative effects of lean, leagile, and agile leveraging our comprehensive framework of practices. Specifically, our contribution identifies practice combinations that can be considered more valuable performance enhancers than others. Furthermore, our research guides managers on aligning and adapting lean, leagile, and agile practices with their firms' strategic priorities and performance goals. Finally, we showcase areas that require additional empirical investigation.
Impact of chromafenozide on the expression of Halloween gene and nuclear receptor gene in Tetranychus cinnabarinus (Boisduval)
Authors: Xin Tianrong , Zhang Xiaojing , Yang Cui , Ye Xianyan , Zou Zhiwen , Xia Bin 
Published: June 2024

AbstractTetranychus cinnabarinus (Boisduval), a worldwide acarine pest, has garnered significant attention in recent studies, particularly regarding the role of ecdysteroids. Ecdysteroids (moulting hormone) played key roles in regulating the important physiological processes of arthropods, such as ecdysis, metamorphosis reproduction and immunity. However, the underlying mechanisms of ecdysteroid biosynthesis and signalling have not been elucidated in T. cinnabarinus. Therefore, in this study, we utilized RACE technology in conjunction with RT‐PCR to obtain the complete sequence of three Halloween genes disembodied (dib), shadow (sad), shade (shd) and ecdysone receptor (EcR). Moreover, we analysed the expression level of these target genes in T. cinnabarinus, which was found to be expressed at all developmental stages. When using sublethal concentration of chromafenozide for bioassay on nymph of T. cinnabarinus, as the concentration increased, the ecdysis rate, mortality and ecdysteroid content were increased, and the moulting duration was decreased. We also characterized the expression on nymph of T. cinnabarinus after treatment with sublethal concentrations of chromafenozide, which were up‐regulated. Based on these findings, we concluded that the treatment of sublethal chromafenozide enhanced Halloween gene and nuclear receptor gene expression, aided in the investigation of the molecular regulatory mechanism for moulting of T. cinnabarinus, and provided a theoretical basis for new agents.
Assessment of Azorean native strains of Heterorhabditis bacteriophora for the biological control of Popillia japonica
Authors: Garriga Anna , Monteiro Hugo R. , Beltrí Rubén , Frias Jorge , Peñalver Ángel , Teixeira Mario , Toubarro Duarte , Simões Nelson 
Published: June 2024

AbstractEntomopathogenic nematodes (EPNs), especially Heterorhabditis bacteriophora, are promising candidates for biological control of Popillia japonica larvae. Thus, there is a need to study native strains to ensure biological agents adapted to specific environmental conditions to improve their effectiveness in field applications. This work aimed to test the pathogenicity of five Azorean isolates of H. bacteriophora strains to third‐instar larvae of P. japonica under laboratory and semi‐field conditions. All EPNs were able to quickly infect larvae with LT50's ranging between 3.66 and 4.54 days in controlled laboratory conditions. The semi‐field experiment consisted of an EPN application in buried tubes containing five larvae each in May and October. After 15 days, larvae were recovered and confirmed for nematode parasitism. In May, Az29, Az148, Az170, and Az171 displayed a mean of 37% infected larvae per tube. In contrast, EPNs showed a lower infection ability during the experiment in October, and only Az148 maintained the number of parasitized larvae, with a proportion of 40% of infectivity. The results suggest that native EPNs, like Az148, could be better adapted to climatic and edaphic conditions to control P. japonica larvae.