bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical and Correlative Characterization of Individual Nanoparticle in Gap Plasmon Resonator Sensors
Authors: Poungsripong Peeranuch , Kannampalli Vyshnav , Santinacci Lionel , Grosso David , Chatain Dominique , Duché David , Margeat Olivier , Sciacca Beniamino 
Published: June 2024

AbstractPlasmonic nanocavities are receving increased attention from the nanophotonics, nanoelectronics, and quantum optics community due to their ability to confine light in extremely small volumes. Coupling colloidal plasmonic nanocrystals to metal films is an inexpensive approach to fabricate virtually unlimited individual resonators that can be tuned by adjusting nanoparticle size, gap thickness, and refractive index. The focus is on silver nanocubes separated from a gold mirror by thin amorphous dielectric layers (Al2O3, TiO2). The optical response is measured and correlative electron microscopy is performed on a large number (>800) of individual resonators to unveil the statistical distribution of gap plasmon modes and assess systematically their sensitivity. A sensitivity as large as 8 nm/nm to nanocube size variation, 50 nm/nm to Al2O3 thickness variation, and 130 nm/RIU for index change of the spacer layer is found. With the help of numerical simulations, this approach enables to infer a quantitative statistical distribution of molecular coatings present on the nanocubes surface, such as polyvinylpyrrolidone, which can affect the performance of nanoelectronic devices and assess the strategy to remove it. Finally, polarization‐resolved measurements enable to unveil a birefringent behavior when nanocubes are supported on annealed TiO2 layers (2–4 nm).
Exploring Microwave Reconfigurable Intelligent Surface for Wireless VOC Detection: A Comparative Study of Porous and Solid PDMS Interfaces
Authors: Mirzaei Hamed , Niksan Omid , Arjmand Mohammad , Zarifi Mohammad H. 
Published: June 2024

AbstractMicrowave gas monitoring with a low‐profile design and enhanced selectivity remains a persistent challenge. This study introduces an innovative approach employing a real‐time wireless reconfigurable intelligent surface (RIS) for comparative investigation of the interaction of two distinct polydimethylsiloxane (PDMS) interfaces, i.e., solid and porous, with acetone gas molecules. The developed PDMS‐coated microwave RIS detects varying concentrations of acetone vapor by wirelessly monitoring variations in the resonant characteristics of the resonating RIS beneath the sensitive interface. This PDMS‐coated microwave RIS is validated through exposure to incremental (15–75) parts per thousand (ppt) acetone concentrations and demonstrated a sensitivity of ≈4.4 MHz/ppt and ≈4.3 MHz/ppt of acetone for solid and porous PDMS, respectively. Integrating PDMS and microwave‐based RIS systems provides a sensitive tool for tracking the interaction of acetone gas and PDMS and demonstrates this system's capability for sensitive gas detection. This study introduces a unique development in the wireless detection of VOCs and presents a compact and passive approach with enhanced sensitivity, making it suitable for monitoring the interaction of polymers and hazardous VOCs. This technology is particularly suited for use in challenging and hard‐to‐reach environments.
Enzalutamide Sensitizes Castration‐Resistant Prostate Cancer to Copper‐Mediated Cell Death
Authors: Gao Xiang , Zhao Haolin , Liu Jiao , Wang Min , Dai Zhihong , Hao Wenjun , Wang Yanlong , Wang Xiang , Zhang Min , Liu Pixu , Cheng Hailing , Liu Zhiyu 
Published: June 2024

AbstractDespite the initial efficacy of enzalutamide in castration‐resistant prostate cancer (CRPC), inevitable resistance remains a significant challenge. Here, the synergistic induction of copper‐dependent cell death (cuproptosis) in CRPC cells is reported by enzalutamide and copper ionophores (elesclomol/disulfiram). Mechanistically, enzalutamide treatment increases mitochondrial dependence in CRPC cells, rendering them susceptible to cuproptosis, as evidenced by specific reversal with the copper chelator tetrathiomolybdate. This susceptibility is characterized by hallmarks of cuproptosis, including lipoylated protein aggregation and iron‐sulfur cluster protein instability. Interestingly, the mitochondrial matrix reductase, FDX1, specifically correlates with elesclomol sensitivity, suggesting a potential mechanistic divergence between the two copper ionophores. Notably, this synergistic effect extends beyond in vitro models, demonstrating efficacy in 22Rv1 xenografts, mouse Pten p53 knockout organoids. Importantly, enzalutamide significantly enhances copper ionophore‐mediated cytotoxicity in enzalutamide‐resistant cells. Collectively, these findings indicate that enzalutamide and copper ionophores synergistically induce cuproptosis, offering a promising therapeutic avenue for CRPC, potentially including enzalutamide‐resistant cases.
First Principles Study of Aluminum Doped Polycrystalline Silicon as a Potential Anode Candidate in Li‐ion Batteries
Authors: Bhimineni Sree Harsha , Ko Shu‐Ting , Cornwell Casey , Xia Yantao , Tolbert Sarah H. , Luo Jian , Sautet Philippe 
Published: June 2024

AbstractAddressing sustainable energy storage remains crucial for transitioning to renewable sources. While Li‐ion batteries have made significant contributions, enhancing their capacity through alternative materials remains a key challenge. Micro‐sized silicon is a promising anode material due to its tenfold higher theoretical capacity compared to conventional graphite. However, its substantial volumetric expansion during cycling impedes practical application due to mechanical failure and rapid capacity fading. A novel approach is proposed to mitigate this issue by incorporating trace amounts of aluminum into the micro‐sized silicon electrode using ball milling. Density functional theory (DFT) is employed to establish a theoretical framework elucidating how grain boundary sliding, a key mechanism involved in preventing mechanical failure is facilitated by the presence of trace aluminum at grain boundaries. This, in turn, reduces stress accumulation within the material, reducing the likelihood of failure. To validate the theoretical predictions, capacity retention experiments are conducted on undoped and Al‐doped micro‐sized silicon samples. The results demonstrate significantly reduced capacity fading in the doped sample, corroborating the theoretical framework and showcasing the potential of aluminum doping for improved Li‐ion battery performance.
Highly Reversible and Stable Sulfur‐Containing Cathodes for Magnesium Batteries with Two‐Plateau Redox Reactions Enabled by Kinetically Favored Mg─S Decomposition
Authors: Xu Hao , Xie Tian , Li Yue , Sun Fengzhan , Zhang Chao , Li Zhao , Yao Yingying , Li Yinghui , Zhan Yang , Zou Xinshu , Shi Chenyang , Wu Zhao , Laine Richard , Zou Jianxin 
Published: June 2024

AbstractRechargeable magnesium sulfur batteries (MSBs) face issues like polysulfide shuttling, sluggish redox kinetics, and high cost, leading to dissatisfied practical demonstrations. Herein, simple battery configurations utilizing 100% sulfur are proposed on nine collectors and a low‐cost phenolate‐based magnesium complex (PMC) electrolyte to address these problems. Comprehensive studies indicate that the Cu collector is the most conducive to improving battery performance, not only facilitating the generation of magnesium sulfides during discharging but also effectively dissociating Mg─S bonds during charging. Moreover, Cu surfaces can effectively adsorb magnesium polysulfides (MgSx) and induce an insulator‐to‐metal transition of MgS, leading to a more effective suppression of the shuttle effect and the transfer of electrons. MXene interlayers are further introduced between electrodes to inhibit MgSx shuttling and enhance the interfacial electronic conductivity, as reflected by the reinforced high discharge voltage plateau at ≈1.7 V and stable long discharge voltage plateau at ≈1.2 V. The assembled MSBs exhibit the highest reported capacity of 1260 mAh g−1S and an energy density of 1230 Wh kg−1S with a cycle life of over 1000 cycles. This research contributes to the fundamental understanding of rechargeable MSBs and marks a significant advancement in optimizing cell designs for better performance.
Pyridazine‐Promoted Construction of Vinylene‐Linked Covalent Organic Frameworks with Exceptional Capability of Stepwise Water Harvesting
Authors: Mou Kaiwen , Meng Fancheng , Zhang Zixing , Li Xiaomeng , Li Mengqi , Jiao Yang , Wang Zhiheng , Bai Xue , Zhang Fan 
Published: June 2024

AbstractIn this study, we successfully developed two novel vinylene‐linked covalent organic frameworks (COFs) using 2‐connected 3,6‐dimethylpyridazine through Knoevenagel condensation. These COFs featured finely tailored micro‐/nano‐scale pore sizes, high surface areas and stable non‐polar vinylene linkages. Finely resolved powder X‐ray diffraction patterns demonstrated highly crystalline structures with a hexagonal lattice in the AA layer stacking. The resulting one‐dimensional channels possess strong hydrogen‐bond accepting sites arising from the decorated cis‐azo/azine units with two pairs of fully exposed lone pair electrons, endowing the as‐prepared COFs with exceptional water absorption properties. The g‐DZPH‐COF exhibited successive steep water uptake steps starting from low relative pressures (P/PSTA=0.1), with the remarkable water uptake capacity of 0.26 g/g at P/PSTA=0.2 (25 °C), which is the optimal value recorded among the reported COFs. Dynamic vapour sorption measurements revealed the fast kinetics of these COFs, even in the cluster formation process. Water uptake and release cycling tests demonstrated their outstanding hydrolytic stability, durability, and adsorption–desorption retention ability.
Bimetallic Single Atom/Nanoparticle Ensemble for Efficient Photochemical Cascade Synthesis of Ethylene from Methane
Authors: Wang Yin‐Feng , Qi Ming‐Yu , Conte Marco , Tang Zi‐Rong , Xu Yi‐Jun 
Published: June 2024

AbstractLight‐driven photoredox catalysis presents a promising approach for the activation and conversion of methane (CH4) into high value‐added chemicals under ambient conditions. However, the high C−H bond dissociation energy of CH4 and the absence of well‐defined C−H activation sites on catalysts significantly limit the highly efficient conversion of CH4 toward multicarbon (C2+) hydrocarbons, particularly ethylene (C2H4). Herein, we demonstrate a bimetallic design of Ag nanoparticles (NPs) and Pd single atoms (SAs) on ZnO for the cascade conversion of CH4 into C2H4 with the highest production rate compared with previous works. Mechanistic studies reveal that the synergistic effect of Ag NPs and Pd SAs, upon effecting key bond‐breaking and ‐forming events, lowers the overall energy barrier of the activation process of both CH4 and the resulting C2H6, constituting a truly synergistic catalytic system to facilitate the C2H4 generation. This work offers a novel perspective on the advancement of photocatalytic directional CH4 conversion toward high value‐added C2+ hydrocarbons through the subtle design of bimetallic cascade catalyst strategy.
Nano silica grafted on modified polyacrylonitrile fiber improves the interfacial strength of fiber‐reinforced concrete
Authors: Wei Fayun , Xu Xiao , Wang Hailou , Yu Bin , Zhang Guangyu , Zhang Wei 
Published: June 2024

AbstractCement is known to be brittle and usually reinforced with fibers. However, there is a lack of effective chemical bonding between organic fibers and inorganic cement, resulting in a weaker interfacial bonding strength. In this paper, amino hyperbranched polymer (HBP) was used to modify the surface of polyacrylonitrile (PAN) fibers, and then silica nanoparticles (SiO2 NPs) were grafted on the surface of modified PAN fibers to realize the inorganic treatment of organic fibers. The modified PAN fibers applied to cement concrete can significantly enhance the interfacial strength between the fibers and cement. The morphology and chemical composition of the modified PAN fibers were characterized by scanning electron microscope, atomic force microscope, electron energy dispersive spectroscopy, and Fourier transform infrared spectroscopy, and the influence of grafting conditions on grafting effect was analyzed. The results show that SiO2 NPs were evenly distributed on the surface of PAN fiber. When SiO2 NPs concentration was 4%, grafting temperature was 50°C, and grafting time was 4 h, the grafting degree of SiO2 NPs grafted PAN fiber can reach to 1.4%. After coating with SiO2 NPs, the pullout bonding strength of the PAN fiber was increased from 5.5 to 6.5 cN.
Utility of green chemistry for feasible spectrofluorometric determination of trifluridine via metal complexation: Application to dosage forms
Authors: Salem Hesham , Emad Nadeen , Fares Joy , Ahmed Habeba , Kamal Habiba , Zein Dina 
Published: June 2024

AbstractThe goal of the current research was to establish a quick and practical fluorometric technique for trifluridine analysis. The approach relied on the drug's complex formation with the zinc ion to produce a high‐fluorescence product. The fluorescence was further enhanced by adding sodium dodecyl sulfate, and it was observed at 450 nm following excitation at 400 nm. With a determination coefficient of 0.9994, the association between emission intensity and trifluridine concentration was linear between 1 and 125 ng mL−1. The quantitation limit was 0.987 ng mL−1 while 0.333 ng mL−1 was the detection limit. The buffer type, pH and concentration, type of surfactant and concentration, and finally the diluting solvent were among the reaction conditions that were closely examined. With great precision and reliability, the drug in question was quantified using this method in dosage formulations. The proposed method's level of greenness was assessed using two methodologies: the analytical greenness metric (AGREE) and the Green Analytical Procedure Index (GAPI).
Superficial retrocalcaneal bursae and nerves: From anatomy to ultrasound‐guided procedures
Authors: Ricci Vincenzo , Chang Ke‐Vin , Naňka Ondřej , Özçakar Levent 
Published: June 2024

AbstractThe pertinent literature widely describes ultrasound‐guided procedures targeting the retrocalcaneal bursa and the tendon tissue to manage insertional Achilles tendinopathy. Synovial bursae and cutaneous nerves of the superficial retrocalcaneal pad are often overlooked pain generators and are poorly considered by clinicians and surgeons. A layer‐by‐layer dissection of the superficial soft tissues in the retrocalcaneal region of two fresh frozen cadavers was matched with historical anatomical tables of the textbook Traite d'Anatomie Topographique Avec Applications Médico‐Chirurgicales (1909 by Testut and Jacob). An accurate and detailed description of the superficial retrocalcaneal pad with its synovial bursae and cutaneous nerves was provided. Cadaveric dissections confirmed the compartmentalized architecture of the superficial retrocalcaneal fat pad and its histological continuum with the superficial lamina of the crural fascia. Superficial synovial tissue islands have been demonstrated on the posterior aspect of the Achilles tendon in one cadaver and on the posterolateral surface of the tendon in the other one. Digitalization of the original anatomical tables of the textbook Traite d'Anatomie Topographique Avec Applications Médico‐Chirurgicales (1909 by Testut and Jacob) showed five potential locations of the superficial calcaneal bursa and a superficial retrocalcaneal nerve plexus within the Achilles tendon‐fat pad interface. In clinical practice, in addition to the previously described interventions regarding the retrocalcaneal bursa and the tendon tissue, ultrasound‐guided procedures targeting the synovial and neural tissues of the superficial retrocalcaneal pad should be considered to optimize the management of insertional Achilles tendinopathy.
Food and housing insecurity among community college student‐veterans
Authors: Soria Krista M. , Smith Amish B. 
Published: June 2024

AbstractIn this manuscript, the authors examined the rates of food and housing insecurity experienced by student‐veterans enrolled at community colleges in fall 2020. The results of a multi‐institutional survey of student‐veterans at 113 community colleges suggested that 37.6% of community college student‐veterans experienced food insecurity and 52.5% of community college student‐veterans experienced housing insecurity. Additionally, 17.8% of community college student‐veterans experienced homelessness in the past year. The results also suggest that community college student‐veterans who experienced food and housing insecurity had lower grade point averages, higher rates of clinically significant generalized anxiety disorder, and higher rates of clinically significant major depressive disorder. Examples of strategies to support community college student‐veterans experiencing food and housing insecurity are included.
Enhancing Suppression of Chain Transfer via Installing Bulky N‐ortho‐Aryl Substituents into α‐Diimine Nickel System
Authors: Ma Zhanshan , Nie Nan , Pang Wenmin , Chen Ao , Peng Dan 
Published: June 2024

AbstractRecently, the important role of sterically bulky aromatic substituents at the axial position of the metal center for synthesizing high‐performance catalysts were recognized. In this study, a series of α‐diimine nickel complexes with bulky N‐ortho‐aryl substituents were designed and synthesized. The as‐synthesized nickel complexes showed high activities (up to 2.3×107 g ⋅ mol−1 ⋅ h−1) and superior thermostability, giving access to moderately branched polyethylenes (35–86/1000 C) with high molecular weights (up to 197.5×104 g ⋅ mol−1). The polyethylene materials generated by these nickel complexes at 80 °C exhibited outstanding tensile mechanical. In addition, these nickel complexes could also catalyze the copolymerization of ethylene and polar monomer with modest activity (such as undecenoic acid, 10‐undecen‐1‐ol and 6‐chlorohex‐1‐ene), yielding functionalized polyolefin with adjustable molecular weights (6.8–222.9×104 g ⋅ mol−1) and incorporation ratios (0.2–4.3 mol %).
Old Yellow Enzymes as Oxime Reductases: New Variants by Substrate‐Based Enzyme Engineering
Authors: Polidori Nakia , Breukelaar Willem B. , Stelzer Svila , Reiter Tamara , Glueck Silvia M. , Kroutil Wolfgang , Gruber Karl 
Published: June 2024

AbstractThe reduction of oximes was recently identified as a promiscuous activity of Old Yellow Enzymes (OYEs). This reaction involves a two‐step reduction of α‐oxime‐ß‐ketoesters to the corresponding amines, which spontaneously dimerise to yield pyrazine derivatives. This biotransformation is currently limited to substrates with small substituents like methyl/ethyl on the keto moiety. We used a structure‐based approach to engineer 12‐oxophytodienoate reductase 3 (OPR3) from Solanum lycopersicum as a prototypical OYE to accept oximes with bulkier substituents. To this end, three single and two double variants were prepared and tested on six oxime substrates. The engineered variants indeed showed activity on some of the bulkier substrates, which had not been converted at all by the wild‐type enzyme, including the diester compound diethyl‐2‐(hydroximino) malonate. While we were unable to identify variants capable of converting substrates with branched and aromatic substituents, the results demonstrate the validity of our engineering approach, suggesting potential pathways for expanding the substrate scope of OYEs.
Multisite Amino‐Allylidene Ligands from Thermal CO Elimination in Diiron Complexes and Catalytic Activity in Hydroboration Reactions
Authors: Zappelli Chiara , Taglieri Francesco , Schoch Silvia , Bresciani Giulio , Funaioli Tiziana , Marchetti Fabio , Zacchini Stefano , Di Giuseppe Andrea , Crucianelli Marcello 
Published: June 2024

AbstractThe new diiron(I) complexes [Fe2Cp2(μ‐CO){μ‐k3C,kN‐C(R1)C(R2)C(CN)NMe(R)}], 3 a–o (R=alkyl or 4‐C6H4OMe; R1=alkyl, aryl, ferrocenyl (Fc), thiophenyl, CO2Me or SiMe3; R2=H, Me or CO2Me) were synthesized in moderate to high yields from the thermal decarbonylation of the bis‐carbonyl precursors 2 a–o, and were structurally characterized by IR and NMR spectroscopy, and single crystal X‐ray diffraction in four cases. Electrochemical behavior of one complex was also investigated. Complexes 3 a–o comprise a highly functionalized, multisite amino‐(cyano)allylidene ligand, including metal coordination of a tertiary amine group. Selected complexes displayed negligible to moderate catalytic activity in CO2/propylene oxide coupling, working under ambient conditions. Additionally, they were investigated as catalysts for the conversion of benzaldehyde to the corresponding borate ester 6 a, using pinacolborane (HBpin) as the borylating agent. Most complexes achieved good conversions at room temperature with 1 % catalyst loading, and data highlight the significant influence of the multisite ligand substituents on the catalytic performance. Notably, complex 3 m (featuring R=4‐methoxyphenyl, R1=Fc, R2=H) displayed the highest activity and effectively catalyzed the hydroboration of various aldehydes and ketones. A plausible mechanistic cycle involves metal coordination of the carbonyl substrate, its activation being possibly facilitated by intramolecular interactions.
Multiscale structural NaTi2(PO4)3 anode for sodium‐ion batteries with long cycle, high areal capacity, and wide operation temperature
Authors: Xu Guobao , Yang Liyue , Yan Zhihao , Huang Zhikai , Li Xue , Guo Gencai , Tian Ye , Yang Liwen , Huang Jianyu , Liang Yaru , Chou Shulei 
Published: June 2024

AbstractThough plenty of research has been conducted to improve the low intrinsic electronic conductivity of NASICON‐structured NaTi2(PO4)3 (NTP), realizing sodium‐ion batteries with high areal/volumetric capacity still remains a formidable challenge. Herein, a multiscale design from anode material to electrode structure is proposed to obtain a gadolinium‐ion‐doped and carbon‐coated NTP composite electrode (NTP‐Gd‐C), in which gadolinium ion doping, oxygen vacancy, optimized structure, N‐doped carbon coating, and bridging on the three‐dimensional network are simultaneously achieved. In the whole electrode, the excellent hierarchical electronic/ionic conductivity and structural stability are simultaneously improved via the synergistic optimization of NTP‐Gd‐C. As a result, excellent electrochemical performances of NTP‐Gd‐C electrode with a high areal/volumetric capacity of 1.0 mAh cm−2/142.8 mAh cm−3, high rate capability (58.3 mAh g−1 at 200 C), long cycle life (ultralow capacity fading of 0.004% per cycle under 10,000 cycles), and wide‐temperature electrochemical performances (97.0 mAh g−1 at 2 C under −20°C) are achieved. Moreover, the NTP‐Gd‐C//Na3V2(PO4)3/C full cell also delivers an excellent rate capacity of 42.0 mAh g−1 at 200 C and long‐term high‐capacity retention of 66.2% after 4000 cycles at 20 C.