bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Prospective Randomized Multicenter Comparison on Health‐Related Quality of Life: The Value of Add‐On Arrhythmia Surgery in Patients with Paroxysmal, Permanent or Persistent Atrial Fibrillation Undergoing Valvular and/or Coronary Bypass Surgery
Authors: VAN BREUGEL H. N. A. M. , NIEMAN F. H. M. , ACCORD R. E. , VAN MASTRIGT G. A. P. G. , NIJS J. F. M. A. , SEVERENS J. L. , VRAKKING R. , MAESSEN J. G. 
Published: November 2009

Quality of Life After Add‐on Arrhythmia Surgery Introduction: This is a multicenter, prospective, randomized controlled trial to determine the effect of add‐on arrhythmia surgery on health‐related quality of life during 1‐year follow‐up of cardiac surgery patients with atrial fibrillation.
Methods:
150 patients with documented atrial fibrillation were randomly assigned to undergo cardiac surgery with or without add‐on surgery. Patients completed quality of life questionnaires, comprising the RAND 36‐item Health Survey 1.0 (SF‐36), Multidimensional Fatigue Inventory‐20 (MFI‐20) and EuroQoL (EQ‐5D and VAS) at baseline and 3, 6, and 12 months following operation.
Results:
132 patients completed the questionnaires at a minimum of one time‐point during follow‐up. At baseline patient characteristics, operative data and health‐related quality of life were comparable. At 12‐month follow‐up 62 patients were free of atrial fibrillation without significant differences between groups (P = 0.28). Conversion to SR occurred in 69.8% (37/53) of patients with paroxysmal AF, in 28.2% (11/39) of patients with permanent AF and in 44.4% (12/27) of patients in persistent AF. Cardiac surgery in general resulted in an overall improvement of the RAND SF‐36 and the MFI‐20. However, the EQ‐5D showed a significant deterioration in the subscale Pain/Discomfort for both groups (P < 0.001), with a significant worse outcome for the control group (P = 0.006).
Conclusions:
Health‐related quality of life in patients with paroxysmal, permanent and persistent atrial fibrillation improves after cardiac surgery regardless of giving add‐on surgery or not, but this improvement is presumably more affected by treating the underlying heart disease than by restoring sinus rhythm. (J Cardiovasc Electrophysiol, Vol. 21, pp. 511‐520, May 2010)
Initial Experience Using a Radiofrequency Powered Transseptal Needle
Authors: SMELLEY MATTHEW P. , SHAH DIPAK P. , WEISBERG IAN , KIM SUSAN S. , LIN ALBERT C. , BESHAI JOHN F. , BURKE MARTIN C. , KNIGHT BRADLEY P. 
Published: November 2009

Introduction:
The purpose of this study was to determine the safety and efficacy of using a novel radiofrequency (RF) powered transseptal needle to perform transseptal puncture (TSP).
Methods:
TSP was performed in 35 consecutive patients undergoing left‐sided catheter ablation (mean age = 51 years; male = 71%) using a RF powered transseptal needle (NRG, Adult Large and Standard Curve C1, 71 cm, Baylis Medical Company, Inc.). Prior TSP had been performed in 34% of patients. The transseptal apparatus was positioned with the tip of the dilator engaged in the fossa ovalis. RF energy was delivered to the tip of the transseptal needle using a proprietary RF generator at 10 W for 2 seconds as gentle pressure was applied to the needle.
Results:
In 5 of the 41 TSPs, the needle crossed into the left atrium before RF energy was delivered. In 35 of the remaining 36 punctures, the needle was successfully advanced into the left atrium after application of RF current. In 1 patient, the TSP with the powered needle was unsuccessful but was accomplished using a standard needle. The only complication was a transient right atrial thrombus, which occurred in 2 patients.
Conclusion:
A radiofrequency powered transseptal needle can be used to perform TSP safely and successfully without the need for significant mechanical force, even in patients who have undergone TSP previously. Additional studies are needed to determine whether a powered transseptal needle should be used routinely. (J Cardiovasc Electrophysiol, Vol. 21, pp. 423–427, April 2010)
Brésil: les leçons de la flexibilisation des années quatre‐vingt‐dix
Authors: POCHMANN Marcio 
Published: November 2009

Résumé.La trajectoire sociale suiviepar le Brésil des années trente à soixante‐dix a connu un changement de cap lors de la crise de la dette de 1981–1983. On a alors commencéà démanteler les régimes du travail et de la protection sociale mis en place pendant ces cinquante années à lafaveur de l'urbanisation et de l'expansion de l'industrie et du travail salarié. Les politiques néolibérales n'ontpas suscité un dynamisme économique suffisant, le chômage et la précarité du travail se sont aggravés. Depuis la fin de 2002, le projet de société néolibérale est progressivement abandonné.
Mexique: persistance d'un système porteur d'exclusion
Authors: BAYÓN María Cristina 
Published: November 2009

Résumé.Au Mexique, le virage néolibéral pris par les politiques sociales et du travail à partir des années quatre‐vingt a aggravé les inégalités, la pauvreté et l'exclusion sociale. Le changement de cap de la dernière décennie ne s'est pas accompagné d'une révision critique du modèle économique et de ses conséquences sociales. Le rôle de l'Etat en matière sociale a été systématiquement réduit, les services sociaux mercantilisés et la protection informelle, fondée sur la famille, s'est étendue. On a ainsi maintenu un modèle social qui ne protège presque exclusivement que les indigents.
Compatibility of the insect pathogenic fungus Beauveria bassiana with neem against sweetpotato whitefly, Bemisia tabaci, on eggplant
Authors: Islam Md. Touhidul , Castle Steven J. , Ren Shunxiang 
Published: November 2009

AbstractA study on the compatibility of the entomopathogenic fungus Beauveria bassiana (Balsamo) Vuillemin (Ascomycota: Hypocreales) with neem was conducted against sweetpotato whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), on eggplant. Initially, three concentrations of B. bassiana (106, 107, and 108 conidia ml−1) and three concentrations of neem (0.25, 0.5, and 1.0%) were used as individual treatments against B. tabaci. The highest concentration of B. bassiana yielded the highest B. tabaci egg (25.2%) and nymph mortalities (73.0%), but this was not significantly different from the mortalities caused by the 107 conidia ml−1 suspension. Similarly, the highest concentration of neem yielded the highest egg (27.3%) and nymph mortalities (75.5%), which was also not significantly different from the 0.5% suspension. Therefore, 0.5% neem was used along with 107B. bassiana conidia ml−1 suspension as an integrated pest management program against B. tabaci. The combination of B. bassiana and neem yielded the highest B. tabaci egg (29.5%) and nymph mortalities (97.2%), and the lowest LT50 (2.08 day) value. Moreover, an integrated combination of B. bassiana with neem caused 27.6 and 20.5% more nymphal mortality than individual treatments of B. bassiana and neem, respectively, 7 days post‐application. Thus, a combined application of an entomopathogenic fungus and a botanical insecticide may benefit from both, and it has proven effective for the control of B. tabaci on eggplant.
Folivorous larvae on flowers: do autumnal moths benefit from catkins of the mountain birch?
Authors: Klemola Tero , Kaitaniemi Pekka , Ruohomäki Kai 
Published: November 2009

AbstractImmature leaves of birches and other deciduous trees and shrubs are the principal food resource for the larvae of the autumnal moth, Epirrita autumnata (Borkhausen) (Lepidoptera: Geometridae). However, the larvae of this geometrid, which displays pronounced population cycles and causes massive forest defoliations in northernmost Europe, are also frequently found on the catkins of mountain birch, Betula pubescens ssp. czerepanovii (Orlova) Hämet‐Ahti (Betulaceae). To examine whether autumnal moth larvae visit birch catkins for their high nutritional value, we conducted two growth experiments in which the larval diet was supplemented with male catkins, and a single test where female catkins were used. We found that the presence of male catkins in the larval diet had a positive effect on the larvae, in relation to their pupal mass (reflecting life span fecundity), survival probability, as well as the duration of the larval period. The presence of female catkins in the diet did not affect larval performance. Our findings suggest that young autumnal moth larvae actively move to male catkins, which provide a nutritional benefit and thus lead to a better performance compared with those feeding elsewhere. Another possible benefit for young larvae choosing the catkins instead of leaves may involve predator or parasitoid avoidance.
Prognostic role of insulin‐like growth factor receptor‐1 expression in small cell lung cancer
Authors: CHANG MYUNG HEE , LEE JEEYUN , HAN JOUNGHO , PARK YEON HEE , AHN JIN SEOK , PARK KEUNCHIL , AHN MYUNG‐JU 
Published: November 2009

Chang MH, Lee J, Han J, Park YH, Ahn JS, Park K, Ahn M‐J. Prognostic role of insulin‐like growth factor receptor‐1 expression in small cell lung cancer. APMIS 2009; 117: 861–9.Insulin‐like growth factor receptor‐1 (IGFR‐1) is a cellular membrane receptor which is overexpressed in many tumors and seems to play a critical role in anti‐apoptosis. The insulin‐like growth factor binding protein‐3 (IGFBP‐3) is known as a growth suppressor in multiple signaling pathways. The aim of this study was to determine IGFR‐1 and IGFBP‐3 expression in small‐cell lung cancer (SCLC) and analyze the prognostic value in patients with SCLC. We analyzed IGFR‐1 and IGFBP‐3 expression in 194 SCLC tissues by immunohistochemical staining. Correlative analyses between IGFR‐1 and IGFBP‐3 expression in SCLC and clinicopathologic factors were performed. A total of 117 patients had extensive disease (ED) (60.3%) and 77 had limited disease (39.7%). With the median follow‐up duration of 49.5 months (24–82 months), the median progression‐free survival (PFS) and overall survival (OS) were 7.2 months [95% confidence interval (CI): 6.4–8.0 months] and 14.4 months (95% CI: 12.7–16 months), respectively. IGFR‐1 expression was observed in 154 of the 190 tumor tissues, whereas there was no IGFBP‐3 expression. Multivariate analysis showed that stage (p < 0.001), response rate (p < 0.001), and lactate dehydrogenase (LDH) levels (p < 0.001) were the independent prognostic factors for PFS, and age (p = 0.014), LDH level (p < 0.001), and stage (p < 0.001) for OS. The IGFR‐1 positivity was not associated with PFS or OS in the entire cohort. Subgroup analysis revealed that OS was significantly longer in patients with IGFR‐1‐positive tissue than IGFR‐1‐negative tissue in SCLC‐ED (p = 0.034). These results suggest that IGFR‐1 expression may be useful as a prognostic marker in patients with SCLC‐ED.
Comparison of 11 endogenous control genes for normalization of mRNA obtained from paraffin‐embedded tissues
Authors: PAI REKHA , SAMUEL PRASANNA , NEHRU ARUN G. , MANIPADAM MARIE THERESE , THOMAS SUSANNA N. 
Published: November 2009

Pai R, Samuel P, Nehru AG, Manipadam MT, Thomas SN. Comparison of 11 endogenous control genes for normalization of mRNA obtained from paraffin‐embedded tissues. APMIS 2009; 117: 886–92.Real‐time reverse transcriptase PCR (RT‐PCR) based assays are being increasingly used in characterization of gene expression. Good quality mRNA is an essential prerequisite for such assays. While fresh tissues provide quality mRNA, the same may not be true of tissues which are formalin‐fixed and paraffin‐embedded (FFPE). This emphasizes the need to identify a good endogenous control gene to normalize for differences in quality and RNA recovery. We attempted to characterize gene expression patterns of 11 commonly used endogenous control genes among 20 FFPE tissues (both neoplastic and normal). Pearson’s coefficient of correlation was determined by comparing the expression of each gene against the mean expression of all other genes. β2 microglobulin (β2M) and β‐actin (βA) (r = 0.95 and 0.94, respectively) were found to be stably expressed across all tissues. However, βA had greater accuracy (2 × SD) than β2M and therefore may be a better choice of an endogenous control for experiments that require normalization while using FFPE tissues.
Four cases of distinctive meningiomas with Zellballen growth pattern
Authors: DONG YINGCHUN , ZHOU XIAOJUN , WU BO , WANG JIANDONG , MA HENGHUI , ZHOU HANGBO , JIANG SHAOJUN , LU GUANGMING , HU QIUJU 
Published: November 2009

Dong Y, Zhou X, Wu B, Wang J, Ma H, Zhou H, Jiang S, Lu G, Hu Q. Four cases of distinctive meningiomas with Zellballen growth pattern. APMIS 2009; 117: 936–40.Meningiomas are attributed to those tumours with slow‐growing pattern occurring predominantly in middle‐aged or elderly patients. Fifteen histological variants have been described based on the variable histomorphological features. Herein we report four cases with specific Zellballen growth pattern, giving the tumours a ‘paraganglioma‐like’ general aspect. The diagnosis of meningiomas was confirmed by immunohistochemical and ultrastructural findings. Histopathologists should be aware of this specific morphology which can lead to misdiagnosis.
Prevalence of Chlamydophila pneumoniae is higher in aorta and coronary artery than in carotid artery of coronary artery disease patients
Authors: JHA HEM C. , SRIVASTAVA PRAGYA , DIVYA AABHA , PRASAD JAGDISH , MITTAL ARUNA 
Published: November 2009

Jha HC, Srivastava P, Divya A, Prasad J, Mittal A. Prevalence of Chlamydophila pneumoniae is higher in aorta and coronary artery than in carotid artery of coronary artery disease patients. APMIS 2009; 117: 905–11.Coronary artery disease (CAD) is a public health problem accounting for an estimated one‐third of deaths overall. A potential link between infectious agents and atherosclerosis has been suggested. Data obtained from several seroepidemiological studies have suggested that infection with Chlamydiophila pneumoniae, Helicobacter pylori, cytomegalovirus and herpes simplex virus‐1 can initiate or maintain the atherosclerotic process. However, there is no single study in which multiple infectious agents have been detected together in different vascular locations in the same population. This would help in determining if there is any leading pathogen in atheromatous plaques of CAD patients. Hence, we screened for C. pneumoniae, H. pylori, CMV and HSV‐1 in different vascular locations of CAD patients using quantitative real‐time (RT) PCR. We performed multiplex RT‐PCR for detecting pathogens, viz. C. pneumoniae, H. pylori, CMV and HSV‐1 in different vascular locations of CAD patients. Percent positivity scores for C. pneumoniae, H. pylori, CMV and HSV‐1 in different vascular locations were as follows: aorta (64.7, 35.3, 11.7 and 11.7 respectively); carotid (27.2, 27.2, 9 and 0 respectively); coronary artery (58.3, 33.3, 16.6 and 8.3 respectively). Combined positivity for C. pneumoniae (C. pneumoniae IgA and RT‐PCR for C. pneumoniae) was the highest compared with all other groups. Aorta and coronary artery were more susceptible to these pathogens as compared with carotid artery. Moreover, CAD patients’ characteristics were associated with C. pneumoniae positivity (C. pneumoniae IgA and RT‐PCR), suggesting thereby that C. pneumoniae may have caused chronic persistent infection in CAD.
Superficially invasive transitional cell carcinoma of the bladder associated with distant cutaneous metastases
Authors: Swick Brian L. , Gordon Jennifer R.S. 
Published: November 2009

Cutaneous metastases from transitional cell carcinoma of the bladder are rare and most often associated with a deeply invasive primary tumor. This case report describes a 69‐year‐old male with previously resected superficially invasive primary transitional cell carcinoma of the bladder who presented with distant cutaneous and central nervous system metastases associated with recurrent bladder cancer. In addition, this case highlights the differential diagnosis of metastatic carcinomas that display a CK7/CK20 positive immunophenotype including transitional cell carcinoma, pancreatic carcinoma, cholangiocarcinoma and rare gastric carcinomas.Swick BL, Gordon JRS. Superficially invasive transitional cell carcinoma of the bladder associated with distant cutaneous metastases.
Antibody buffering of systemically administered lysozyme*
Authors: O’Hear Carol , Foote Jefferson 
Published: November 2009

Abstract Objective: To assess the ability of an anti‐lysozyme antibody to stabilize the plasma pharmacokinetics of lysozyme through a ‘buffering’ effect. Methods: Hen egg lysozyme was radiolabeled with 14C and infused with or without the murine anti‐lysozyme antibody D1.3 into the jugular vein of rats. The dosages of antibody and lysozyme were varied, and the antibody and lysozyme were administered either together or in separate infusions. Results: Buffering of lysozyme with an equimolar amount of D1.3 more than doubled the plasma half‐life of lysozyme and addition of more antibody buffer prolonged the half‐life to an even greater extent. D1.3 bound lysozyme that was infused several minutes after the D1.3 administration, indicating that D1.3 can be charged with drug in vivo. Conclusion: Antibody buffering of monovalent therapeutic enzymes is possible and may have potential for clinical use.
Remission of extensive intrahepatic metastasis by C‐arm computed tomography guided chemoembolization in uveal melanoma
Authors: Sunderkötter Cord , Eickelmann Mareike , Köhler Michael , Schmittel Alexander , Wacker Frank K. 
Published: November 2009

SummaryAs soon as uveal melanoma has metastasized to the liver, response rates to systemic chemotherapy are low. It can be improved by development of special locoregional procedures. A 24‐year‐old woman suffered from inoperable hepatic metastases which grew to life‐endangering size despite both systemic chemotherapy with gemc‐itabine/treosulfan and conventional intrahepatic chemoembolization with fotemustine and starch particles. We subsequently performed two angiographic C‐arm CT‐guided, superselective chemoembolizations of the hepatic arteries feeding the tumor, using cisplatin, starch microspheres and ethiodized oil. Following this treatment, no vital tumor tissue was detectable by MRI. This remission lasted for more than 6 months and the patient's quality of life was good. A subsequent local relapse could not be treated with chemoembolization because of thrombosis of the portal vein due to tumor compression. And the patient died 20 months after first detection of metastases. However, the selective angiographic C‐arm CT‐guided chemoembolization resulted in prolongation of life with good quality despite the advanced stage of the disease.
Root and rhizome systems of perennial grasses grown in Inner Mongolian grassland, China
Authors: Ao Min , Miura Reiichi , Tominaga Tohru 
Published: November 2009

AbstractThe root and rhizome systems of dominant perennial grasses in Inner Mongolian grassland were clarified. We surveyed the vertical distribution of root and rhizome biomass in the natural stands, and the changes of under‐ground biomass and the branching pattern of rhizomes for transplanted plants in a container experiment. Most roots of Leymus chinensis, Bromus inermis, Elymus dahuricus and Agropyron cristatum were distributed in the soil depth of 0–10 cm. Roots of E. dahuricus and A. cristatum were distributed in a shallower soil layer, but those of L. chinensis and B. inermis were distributed in a deeper soil layer. Biomass of above‐ground parts increased with growth, resulting in a decreasing ratio of under‐ground parts to total biomass. Rhizomes of L. chinensis and B. inermis were distributed in the soil depth of 0–10 cm, but E. dahuricus and A. cristatum did not have rhizomes. L. chinensis had longer rhizomes and new ramets were produced away from their mother plant. B. inermis had many short rhizomes and produced daughter plants near their mother plant.
Frequency of androgenesis in Poa arachnifera interspecific hybridizations
Authors: Kindiger Bryan , Wipff Joseph 
Published: November 2009

AbstractAndrogenic dihaploids represent a unique form of dihaploids that have historically been utilized for cytoplasmic transfer, the generation of inbred lines and polyploid genome manipulations. Due to the apomictic nature of many Poa species, breeding improvements can be slow and difficult; therefore, alternative approaches that can capitalize on sampling the genetic diversity of near obligate Poa could be advantageous. This study investigates the frequency and potential use of androgenic derived dihaploids generated from a series of Poa arachnifera (Texas bluegrass) × Poa secunda (Sandberg bluegrass), Poa pratensis (Kentucky bluegrass) and Poa ligularis (Argentine bluegrass) interspecific hybrids. The examination of 2041 F1 hybrids generated from three interspecific hybridizations, confirmed the generation of 31 dihaploid individuals. Though low in occurrence, the generation of androgenic dihaploids derived through P. arachnifera interspecific hybridizations offers a non‐traditional breeding approach for sampling genetic variability of Poa species and the development of new breeding resources.
Utilizing single primers as molecular markers inPoaspp.
Authors: Kindiger Bryan , Conley Terry R. 
Published: November 2009

AbstractAn approach is described whereby single simple sequence repeat (SSR) primers are utilized at high annealing temperature to identify and evaluate the presence of palindrome or quasi‐palindrome regions in polyploid genomes to provide locus specific genotyping for polyploid grass species. The procedure has been effective in identifying markers that coexpress inPoa arachniferaand interspecificPoahybrids. DNA sequence analysis of the polymerase chain reaction (PCR) amplification products identified an array of homologous loci within and among evaluated individuals. From this study, 157 single primers were identified to provide information and identify polymorphisms acrossP. arachnifera. Similar to random amplified polymorphic DNA, arbitrarily primed PCR or low‐stringency single primer PCR methods, this approach requires no prior genome information, utilizes agarose gels and can be visualized with ethidium bromide. Preliminary evaluations of additionalPoaspp.,Bromus inermis,Dactylis glomerata,Thinopyrum ponticum,Lolium perenneandAgrostisspp. suggest wide utility of this approach toward genotyping polyploid grasses.
Differences in spectrum reflectance and physiological indices among three typical semi‐natural grasslands in Japan
Authors: Tomimatsu Hajime , Itano Shiro 
Published: November 2009

AbstractTo clarify the utility of spectrum reflection from plant canopy surfaces for distinguishing grassland vegetation, we tested a portable hyper‐spectrometer in three typical Japanese semi‐natural grasslands: Zoysia‐dominated (Z), Pleioblastus‐dominated (P), and mixed species types (Mixed). We calculated the spectrum reflectance, its coefficient of variation (CV) and first derivative reflectance (FDR), and three physiological indices (PRI, photochemical reflectance index; CCI, canopy chlorophyll index; CI, chlorophyll index). The CV of waveform reflectance in the Mixed grassland tended to be higher than those in Z‐ and P‐dominated grasslands. The values of PRI, CI and CCI differed among the three grasslands (P [PRI = −0.027, CCI = 1.469, CI = 0.550] > Mixed [−0.031, 1.421, 0.459] > Z [−0.042, 1.297, 0.428]). Therefore, the CV may be used to distinguish grasslands dominated by a single species from those dominated by multiple species, while the physiological indices may be able to distinguish the grassland type by its dominant species.