bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE FATE OF THE STATE ACADEMY FOR THE HISTORY OF MATERIAL CULTURE AT THE TURNING POINT: AN UNDISPATCHED LETTER OF F.V. KIPARISOV TO S.M. KIROV
Authors: Zastrozhnova Evgenia G. , Medvedeva Maria V. 
Published: April 2024

In 1934, the Academy for the History of Material Culture (SAHMC), a leading archaeological institution of Russia, faced a challenge. The Chairman of SAHMC, Academician Nikolai Ya. Marr, who had headed it for many years, was dying, and urgent measures had to be taken to ensure successful work of the Academy after his death. Deputy Chairman F.V. Kiparisov decided to address a letter to the party leader of Leningrad Sergey Kirov in order to secure the leading positions of SAHMC in science; he asked for a personal appointment with Kirov to discuss the future of the Academy and proposed a programme for further development of the institution. The drafts of the letter were prepared in November 1934, shortly before the assassination of S.M. Kirov, but the letter itself was probably never sent to the addressee. The papers are kept in the archival collection of SAHMC at Archives of the Institute for the History of Material Culture RAS. Its full publication will provide important new information on the history of SAHMC activities in the context of the general development of Russian academic science during the troubled period of the 1930s.
PROBLEMATIKA BUDAYA HUKUM KONSUMEN DALAM TRANSAKSI ONLINE
Authors: Putri Shely Nasya , Nabila Cindy Firantika 
Published: April 2024

Transaksi online berkembang di dalam masyarakat sebagai dampak dari adanya perkembangan teknologi. Banyak pelaku usaha dan konsumen melakukan transaksi jual beli melalui online. Realitasnya konsumen masih ada yang dirugikan dengan menggunakan transaksi online,hal ini disebabkan karena konsumen masih banyak yang menggunakan transaksi online dengan tidak berhati-hati tidak melihat penilaian atau komentar pada toko. Pihak yang dirugikan tidak melaporkan atau mengadu ketika terjadi sesuatu permasalahan dalam melakukan transaksi online. Padahal konsumen dalam melakukan transaksi online dilindungi oleh Undang-undang No.11 Tahun 2008 Tentang Informasi serta Transaksi Elektronik dan Peraturan Pemerintah No. 71 Tahun 2019 Tentang Penyelenggaraan Sistem dan Transaksi Elektroni dan oleh Undang-undang No. 8 Tahun 1999 yang mengatur tentang perlindungan terhadap konsumen. Konsumen mempunyai kewajiban untuk membaca dan mencari informasi ketika melakukan pembelian dalam transaksi online dan melaporkan permasalahan yang terjadi ketika melakukan pembelian dalam transaksi online. Pentingnya budaya hukum pada konsumen dalam transaksi online karena budaya hukum unsur yang penting dalam sistem hukum, karena budaya hukum memperlihatkan pemikiran masyarakat dalam menentukan bagaimana hukum tersebut ditaati atau tidak.Penelitan ini bertujuan untuk mengetahui bagaimanakah budaya hukum konsumen dalam transaksi online. Pengumpulan data dilakukan dengan menggunakan teknik wawancara dan dokumentasi. Sedangkan analisa data menggunakan metode analisis kualitatif. Hasil dari penelitan yaitu problema budaya hukum konsumen terlihat dari sikap konsumen yang masih kurang berhati-hati dalam melakukan pembelian pada transaksi online, kurangnya pengetahuan konsumen antara membedakan akun-akun penipuan atau bukan pada transaksi online dan kesadaran hukum konsumen dalam transaksi online masih cukup rendah karena lebih memilih diam ketika mengalami permasalahan – permasalahan ketika melakukan transaksi online.
IMPLEMENTASI PEMBELAJARAN STEAM DALAM MENGEMBANGKAN KETERAMPILAN ABAD 21 PADA ANAK USIA DINI
Authors: Ngili Agustina Elisabeth 
Published: April 2024

Usia dini merupakan tahap usia yang sangat rentan dan responsif terhadap lingkungan belajarnya. Sehingga diperlukan pendidikan yang dapat meletakkan dasar dalam pembentukan perilaku dan etika yang luhur serta pengembangan intelektual yang tinggi dengan mengimplementasikan pembelajaran STEAM. Tujuan penelitian ini untuk membuktikan bahwa implementasi pembelajaran STEAM dapat meningkatkan ketrampilan abad 21 pada anak usia dini. Metode penelitian yang digunakan metode kualitatif. Pengumpulan data dilakukan dalam lingkungan alamiah, menggunakan sumber data primer. Metode ini melibatkan observasi aktif, wawancara mendalam, dan dokumentasi sebagai teknik utama untuk mengumpulkan data. Hasil penelitian ini membuktikan bahwa pelaksanaan pembelajaran STEAM membawa kontribusi positif dalam pengembangan keterampilan abad 21, seperti berpikir kritis, kreativitas, kolaborasi, komunikasi, literasi digital, dan keterampilan interpersonal. Pembelajaran STEAM juga dapat membangkitkan minat dan motivasi belajar anak-anak usia dini. Melalui proyek-proyek yang menarik dan eksperimen sains menyuguhkan pengalaman belajar yang menyenangkan, merangsang rasa ingin tahu, dan memotivasi anak-anak.
NEED ANALYSIS OF MOBILE LEARNING AT JUNIOR HIGH SCHOOL IN INDONESIA: A BLIOMETRIC STUDY
Authors: Aprilia Bekti , Japar Muhammad , Paristiowati Maria 
Published: April 2024

This research examines the need for mobile learning at Indonesia's junior high school. Mobile learning is a learning approach that uses mobile devices and digital technology to support the learning process. This research aims to understand research trends related to mobile learning and the need for mobile learning in Indonesian junior high schools. This research uses bibliometric analysis to evaluate mobile learning research trends in Indonesian junior high schools. Bibliometric analysis involves collecting and analyzing relevant bibliographic data or scientific publications. The research uses four application tools. First, Publish or Perish was used to search for scientific articles by keyword, resulting in 752 articles. Then, through Mendeley, filtering was carried out based on specific criteria, resulting in 561 articles. Next, Covidence filtered articles in detail, resulting in 158 relevant articles. Finally,VOS viewer is used for data visualization with co-occurrences. The results of the bibliometric analysis show that research on mobile learning in Indonesian junior high schools has increased significantly since 2020. Various disciplines are involved in mobile learning research, primarily focusing on mathematics, science, and language education. Apart from that, the field of information technology also has a vital role in developing mobile learning applications and infrastructure. This research provides an objective view of research trends and mobile learning needs in Indonesian middle schools, provides direction for further research, and supports the development of more innovative and inclusive education in the future.
AUGMENTED REALITY IN EDUCATION: A BIBLIOMETRIC ANALYSIS
Authors: Nirmala Besse , Solihatin Etin , Sukardjo Moch. 
Published: April 2024

The application of augmented reality in education has become increasingly important in recent years. This research aims to reveal trends over the last twenty years with bibliometric analysis to examine the results of articles related to the use of augmented reality in education. This research collects data from the Scopus database from 2003 to 2023, uses the Scopus website analysis features, and visualizes the bibliometric network using Vosviewer. A total of 1,772 studies were accessed through various screening processes. This research distributes publications based on year, country, author, and most cited articles. Among the most published articles indexed by Scopus, papers published by researchers in the United States have the highest number of publications (302), followed by Spain (166) and China with 131 publications. Computer science provided the largest contribution by subject area (858 articles). The five most popular journals in AR are Education and Information Technologies, Computers and Education, Education Sciences, Sustainability Switzerland, and the International Journal of Emerging Technologies in Learning. It has been detected that Wu H.-K. et al. are the most popular authors, with a citation level reaching 3022 citations. The concepts that became clear in the co-occurrence analysis group were “augmented reality," “virtual reality," "education," "teaching," “students,” and "e-learning.”
IMPROVING THE ABILITY TO UNDERSTAND AND SOLVE MIXED AUTOMATION OPERATIONS THROUGH LEARNING MODELS STUDENT TEAMS-ACHIEVEMENT DIVISIONS (STAD) FOR CLASS VI PRIMARY SCHOOL STUDENTS
Authors: Mardiansah Andika 
Published: April 2024

This research aims to increase motivation and learning outcomes in Mathematics through the Student Teams Achievement Divisions (STAD) learning model. This type of research is classroom action research carried out in two cycles with mixed arithmetic operations as the material. The subjects of this research were class VI students at SD Negeri 1 Talagening, Bobotsari, Purbalingga, Central Java, totaling 24 students in the 2022–2023 academic year. This research was carried out in 2 cycles, each consisting of 2 meetings and each meeting included the planning, implementation, observation and reflection stages. The action hypothesis in this research is that the use of the STAD-type learning model increases motivation and Mathematics learning outcomes.
An indicator of success is when student activity in the learning process reaches a score of 75% or more. The average class score for each cycle is at least 75. Students who achieve a score of 75 or 80% of the total number of students. Based on the results of observations of students, it was 37.50% in cycle I, meeting 1 and 58.33% in meeting 2. Meanwhile, in cycle II, meeting 1, the score was 70.83% and in meeting 2, the score was 83.33%. The number of students who obtained a score of 75 or more in cycle I was 16 students or 66.67%, while in cycle II there were 21 students or 87.50%. In cycle II and the final results it was found that students had exceeded the specified success indicators.
PENGARUH KEBIJAKAN SUPERVISI PIMPINAN TERHADAP KINERJA GURU DI SMP NEGERI 14 PESAWARAN
Authors: Nilasari Oktavia , Helmita Helmita 
Published: April 2024

Pengaruh kebijakan Supervisi Pimpinan (Kepala Sekolah) terhadap kinerja guru di SMP Negeri 14 Pesawaran. Sampel guru yang digunakan adalah seluruh guru yang ada di SMP Negeri 14 Pesawaran 30 guru dengan teknik populasi. Analisis yang digunakan meliputi uji validasi data, uji rehabilitas, analisis regresi berganda, Uji t, dan Uji F. Hasil penelitian menunjukan variable independen seperti pimpinan (X), berpengaruh terhadap kinerja guru (Y) pada SMP Negeri 14 Pesawaran. Variabel supervisi Pimpinan / Kepala Sekolah (X) secara parsial berpengaruh signifikan kinerja guru (Y). Kepala Sekolah belum memberikan supervisi yang sesuai dengan kebutuhan dan harapan para guru masih adanya ketidak sesuaian dalam membuat atau melaksanakan supervise yang dilakukan kepala sekolah terhadap guru untuk sebuah penilaian kinerja guru. Dalam system pembelajaran masih di anggap kuranmg maksimal karena dalam system penilaian yang dilakukan pimpinan/kepala sekolah belum sepenuhnya dilaksanakan sesuai juknis (aturan) yang sudah mendajdi ketetapan dari dinas Pendidikan.
Playing the Long Game: China’s market opportunities for Ontario startups (Part 1)
Authors: Mao Xuefei 
Published: April 2024

<p>Canada has a robust startup ecosystem. In Startup Genome’s Startup Ecosystem Report 2012, three Canadian cities (two in Ontario) were ranked among the top 20 most active startup scenes in the world. These numbered among seven cities in the US, one in Israel, three in Europe and several in Asia Pacific. While Canada has the reputation of having excellent innovation capabilities and has witnessed a healthy growth of startups, it is facing similar challenges as Israel and other European countries on the top 20 list. These challenges include a comparably small domestic market and limited early-stage funding support for startups. </p>
Out-of-pocket expenses and rationing of insulin and diabetes supplies: findings from the 2022 T1International cross-sectional web-based survey
Authors: Souris Katherine Janine , Pfiester Elizabeth , Thieffry Axel , Chen Yanbing , Braune Katarina , Kapil Bhargava Mridula , Samra Ravjot , Gómez Pilar , O'Donnell Shane 
Published: April 2024

IntroductionContinue investigating Out-of-Pocket Expenses (OoPEs) and rationing of insulin and diabetes supplies, including impacts of the COVID-19 pandemic, for people with type 1 diabetes (T1D).MethodsA cross-sectional web-based survey was conducted in English and advertised by T1International’s global network of patient advocates from May through September 2022. Participants provided monthly OoPEs and rationing frequency for insulin and supplies, impacts of the COVID-19 pandemic, and open-ended comments.ResultsIn the seven most represented countries, mean monthly OoPEs were highest in the United States, followed by Panama, Canada, and India, and were much lower in the United Kingdom, Germany, and Sweden. OoPEs were highest for participants with partial healthcare coverage, followed by those with no healthcare coverage. The COVID-19 pandemic negatively impacted access and/or affordability of insulin and/or supplies for over half of participants. Globally, 19.5% reported insulin rationing and 36.6% reported rationing glucose testing supplies. Qualitative analysis of open-ended responses identified themes such as ‘mental health impacts’ and ‘limits to life choices.’DiscussionHigh OoPEs lead to rationing of insulin and supplies for many people with T1D globally. Healthcare systems improvements and price reductions of insulin and supplies are needed to ensure adequate, equitable access for all.
Representations of Chagas disease among Bolivian immigrants in the city of São Paulo
Authors: Silveira Cássio , Forsyth Colin , Junior Nivaldo Carneiro , Goldberg Alejandro , da Silva Lia Maria Britto , da Silva Rubens Antonio , Shikanai-Yasuda Maria Aparecida 
Published: April 2024

BackgroundTransnational immigrants are particularly impacted by neglected diseases, which take a heavy biological, social, and emotional toll in these marginalized communities. Chagas disease has transformed from an exclusively rural to an increasingly urban phenomenon encompassing non-endemic areas in Latin America.MethodsThrough semi-structured interviews, we investigated representations of Chagas disease in Bolivian immigrants in São Paulo, Brazil. Between August and September 2015, 27 adult migrants were interviewed, 11 of them with Chagas disease. We explored problems of access to health services and essential knowledge about the disease, as well as related conceptions and health practices.ResultsParticipants constructed social representations of Chagas through interactions with family and social networks, drawing on earlier experiences in Bolivia. Diagnosis often provoked fear, and participants faced barriers to care based on language differences and uncertainties about the disease and treatment options. Healthcare personnel played an important role in alleviating concerns and facilitating access to information.DiscussionThe complex intersection of migration and neglected diseases creates challenges for local and national health programs, requiring innovative responses incorporating the perspectives and needs of the often vulnerable affected communities.
Strongly asymmetric interactions and control regimes in the Barents Sea: a topological food web analysis
Authors: Jordán Ferenc , Capelli Greta , Primicerio Raul , Bodini Antonio 
Published: April 2024

IntroductionIncreasing temperature of the global ocean alters the spatial behavior of a number of species. From the northern Atlantic Ocean, species may shift their area towards the poles. This results in the atlantification of the Barents Sea, raising questions about possible changes in species composition, community structure and community control.MethodsWe address the question whether possible changes in community control can be detected and quantified based on simple network analytical measures applied to the food web. Based on unweighted (binary) and undirected (symmetric) data, we quantify the strength of direct and indirect interactions in the network, represent the most asymmetric effects in the asymmetry graph composed of directed and weighted links and study the overlap among trophic niches of organisms.Results and discussionWe support earlier findings suggesting that the ecosystem can possibly be characterized by wasp-waist control. This would mean that focusing management efforts on intermediate trophic levels is of high importance, providing indirect benefit for organisms also at lower and higher trophic levels.
Presenting clinical and imaging features of patients with clinically amyopathic interstitial lung disease associated with myositis-specific autoantibodies
Authors: Tzilas Vasilios , Tzouvelekis Argyrios , Sotiropoulou Vasilina , Panopoulos Stylianos , Bouros Evangelos , Avdoula Eleni , Ryu Jay H. , Bouros Demosthenes 
Published: April 2024

BackgroundLung involvement in the context of idiopathic inflammatory myopathies has significant impact on outcome; early and accurate diagnosis is important but can be difficult to achieve. In particular, patients without clinically evident muscle involvement pose a significant diagnostic challenge.MethodsA computer-assisted search was conducted to identify patients with amyopathic interstitial lung disease associated with the presence of myositis-specific autoantibodies. Medical records and chest imaging studies were reviewed to identify clinical and radiologic features at presentation.ResultsOf the 35 patients with amyopathic interstitial lung disease associated with myositis-specific autoantibodies, the median age was 65 years (range 43–78) and 20 were women (57%). Of the patients, 34% had previously visited the rheumatology department. Presenting symptoms consisted of dyspnea (94%), cough (43%), and arthritis (23%). Raynaud phenomenon, “mechanic hands,” Gottron papules, and inspiratory crackles were present in 23, 31, 9, and 74% of patients, respectively. After a detailed history, none of the patients reported muscle weakness, while four (11%) exhibited increased CK levels; of these four, two had a concomitant increase in aldolase levels. Median FVC was 79% predicted (range: 49–135) and median DLco was 50% predicted (range: 17–103). HRCT pattern was suggestive of an alternative to UIP pattern in 31/33 (94%) patients; the most common imaging patterns were NSIP (49%) and NSIP/OP (39%).ConclusionIn patients with NSIP and NSIP/OP pattern, the presence of amyopathic interstitial lung disease associated with myositis-specific autoantibodies should be considered even in the absence of clinical evident myositis.
Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy
Authors: Xiaoyu Chang , Hongzhen Zhou , Nan Peng , Tengwei Gao , Yanan Gong , Yan Guo , Haiyan La , Li Ma , Haiya Wu , Yujun Wen , Rui Zhang 
Published: April 2024

ObjectiveTemporal lobe epilepsy (TLE) is a prevalent refractory partial epilepsy seen in clinical practice, with most cases originating from the hippocampus and being characterized by impaired learning and memory. Oxidative stress plays a direct role in the development of epilepsy and neurodegeneration while promoting cognitive dysfunction. Previous research indicates that benzyl isothiocyanate (BITC) has antioxidative stress properties and contributes to neuroprotection. In this study, we aimed to investigate the neuroprotective effect of BITC on a lithium-pilocarpine-induced temporal lobe epileptic mice model.MethodsWe conducted Intellicage learning tests, Morris water maze, open field test, and step-down-type passive avoidance tests, respectively. In addition, body weight and brain-to-body ratio were calculated. Nissl staining, real-time quantitative PCR detection of nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase 1 (HO-1) and NAD(P)H dehydrogenase quinone 1(NQO1) were performed. Content of malondialdehyde (MDA) and activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC) were determined.ResultsOur results demonstrate that BITC enhances cognitive function and motor ability in mice, as determined by Intellicage learning tests, Morris water maze, open field test, and step-down-type passive avoidance tests, respectively. Epilepsy leads to the loss of neurons in the CA3 region, while BITC treatment plays a positive role in neuroprotection, especially in the cortex. In comparison to the control group, the EP group exhibited decreased transcription levels of HO-1 and NQO1, alongside reduced GSH-Px activity, while MDA content was elevated. Conversely, the BITC treatment group, when compared to the EP group, showed enhanced transcription levels of Nrf2, HO-1, and NQO1, along with increased GSH-Px activity, and a decrease in MDA content.ConclusionIn summary, our study provides evidence that BITC can improve cognitive impairments in pilocarpine-induced epileptic mice, demonstrating significant antioxidant effects and neuroprotective properties. This highlights its potential as a phytochemical for managing the sequelae of epilepsy.
LGR6 is a prognostic biomarker for less differentiated tumors in lymph nodes of colon cancer patients
Authors: Eltorky Hagar , AbdelMageed Manar , Ismail Hager , Zahran Faten , Guirgis Adel , Olsson Lina , Lindmark Gudrun , Hammarström Marie-Louise , Hammarström Sten , Sitohy Basel 
Published: April 2024

IntroductionThe aim was to investigate whether the stem cell marker LGR6 has prognostic value in colon cancer, alone or in combination with the prognostic biomarkers CEA and CXCL16.MethodsLGR6 mRNA levels were determined in 370 half lymph nodes of 121 colon cancer patients. Ability to predict relapse after curative surgery was estimated by Kaplan-Meier survival model and Cox regression analyses.ResultsPatients with high LGR6 levels [LGR6(+)] had a decreased mean survival time of 11 months at 5-year follow-up and 47 months at 12-year follow-up, respectively, with hazard ratios of 3.2 and 2.8. LGR6 mRNA analysis added prognostic value to CEA and CXCL16 mRNA analysis. In the poor prognosis groups CEA(+) and CXCL16(+), further division was achieved by LGR6 analysis. LGR6(+) patients had a very poor prognosis. LGR6 also identified a small number of CEA(-), TNM stage I patients who relapsed suggesting stem cell origin of these tumors. LGR6 and LGR5 levels correlated strongly in lymph nodes of stage I and IV patients but not in stage II patients, suggesting that these stem cell markers are differentially regulated.ConclusionThis study highlights LGR6 as a useful prognostic biomarker independently and in combination with CEA, CXCL16 or LGR5 identifying different risk groups.
Role and mechanism of NCAPD3 in promoting malignant behaviors in gastric cancer
Authors: Zhang Su-Yun , Luo Qiong , Xiao Li-Rong , Yang Fan , Zhu Jian , Chen Xiang-Qi , Yang Sheng 
Published: April 2024

Background:Gastric cancer (GC) is one of the major malignancies threatening human lives and health. Non-SMC condensin II complex subunit D3 (NCAPD3) plays a crucial role in the occurrence of many diseases. However, its role in GC remains unexplored.Materials and Methods:The Cancer Genome Atlas (TCGA) database, clinical samples, and cell lines were used to analyze NCAPD3 expression in GC. NCAPD3 was overexpressed and inhibited by lentiviral vectors and the CRISPR/Cas9 system, respectively. The biological functions of NCAPD3 were investigated in vitro and in vivo. Gene microarray, Gene set enrichment analysis (GSEA) and ingenuity pathway analysis (IPA) were performed to establish the potential mechanisms.Results:NCAPD3 was highly expressed in GC and was associated with a poor prognosis. NCAPD3 upregulation significantly promoted the malignant biological behaviors of gastric cancer cell, while NCAPD3 inhibition exerted a opposite effect. NCAPD3 loss can directly inhibit CCND1 and ESR1 expression to downregulate the expression of downstream targets CDK6 and IRS1 and inhibit the proliferation of gastric cancer cells. Moreover, NCAPD3 loss activates IRF7 and DDIT3 to regulate apoptosis in gastric cancer cells.Conclusion:Our study revealed that NCAPD3 silencing attenuates malignant phenotypes of GC and that it is a potential target for GC treatment.