bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the resolvent arising in a parameter‐elliptic multi‐order boundary problem
Authors: Faierman M. 
Published: July 2012

AbstractIn this paper we consider a boundary problem for a parameter‐elliptic, multi‐order system of differential equations defined over a bounded region in \documentclass{article}\usepackage{amssymb}\begin{document}\pagestyle{empty}$\mathbb {R}^n$\end{document} and under limited smoothness assumptions as well as under boundary conditions which include those of Dirichlet. Information is then derived concerning the asymptotic behaviour of the trace of a power of the resolvent of the Hilbert space operator, in general non‐selfadjoint, induced by the boundary problem under null boundary conditions. This information will then be used in a subsequent work to derive various results pertaining to the asymptotic behaviour of the eigenvalues of this operator.
Assessing the reproducibility of dynamic contrast enhanced magnetic resonance imaging in a murine model of breast cancer
Authors: Barnes Stephanie L. , Whisenant Jennifer G. , Loveless Mary E. , Ayers Gregory D. , Yankeelov Thomas E. 
Published: July 2012

AbstractQuantitative dynamic contrast enhanced magnetic resonance imaging estimates parameters related to tissue vascularity and volume fractions; additionally, semiquantitative parameters such as the initial area under the curve can be utilized to describe tissue behavior. The aim of this study was to establish the reproducibility of quantitative and semiquantitative analysis of dynamic contrast enhanced magnetic resonance imaging in a murine model of breast cancer. For each animal, a T1‐weighted, gradient‐echo sequence was used to acquire two sets of dynamic contrast enhanced magnetic resonance imaging data separated by 5 h. Data were acquired at both a 0.05 mm3 (1282, n = 12) and a 0.2 mm3 (642, n = 12) resolution, and analysis was performed using both the Tofts–Kety (to estimate Ktrans and ve) and extended Tofts–Kety (Ktrans, ve, and vp) models. Reproducibility analysis was performed for both the center slice and the total tumor volume for all parameters. For the total volume analysis, the repeatability index for Ktrans is 0.073 min−1 in the standard model analysis and 0.075 min−1 in the extended model analysis at the 1282 acquisition. For the 642 acquisition, the values are 0.089 and 0.063 min−1 for the standard and extended models, respectively. The repeatability index for initial area under the curve was 0.0039 and 0.0042 mM min for the 1282 and 642 acquisitions, respectively. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.
Experimental study of therapy of bone marrow mesenchymal stem cells or muscle‐like cells/calcium alginate composite gel for the treatment of stress urinary incontinence
Authors: Du Xiao‐Wen , Wu Hui‐Ling , Zhu Yong‐Feng , Hu Jun‐Biao , Jin Fan , Lv Rui‐Ping , Sun Si , Wang Hao‐Yu , Xu Jian‐Wei 
Published: July 2012

AbstractObjectiveTo explore the myoblast formation around the urethra and increase in urethral resistance of bone marrow mesenchymal stem cells or muscle‐like cells/calcium alginate composite gel injection therapy and effect on LPP in SUI rat model.MethodsIsolation, cultivation, and identification of SD rat bone marrow mesenchymal stem cell were performed. 5‐Azacytidine was introduced to induce muscle‐like cells. SUI was produced in 72 6‐week‐old female Sprague–Dawley rats, which were divided into four groups: stem cell‐gel group, muscle‐like cell‐gel group, Gel group, and mock control group. One, 4, and 8 weeks after injection, the leak point pressure (LPP) was measured. HE staining of Desmin and α‐skeletal muscle actin (α‐SMA) were performed.ResultsAt 4 and 8 weeks after injection in stem cell‐gel group and muscle‐like cell‐gel group, growth of blood vessels gradually increased at gel edge, BMSC, and muscle‐like cells gathered around the new blood vessels observed by fluorescence tracer, muscle‐like cells grew into elongated spindle‐like cells, Desmin, and α‐SMA staining were obviously positive expression. LPP determinations of the mock control group compared with the Gel groups were significantly different.ConclusionsCompound of BMSC, muscle‐like cells, and calcium alginate composite gel has the potential to differentiate into muscle cells in the microenvironment of SUI rat model. It is found by LPP measurement that the correlation between the increase in urethral resistance and the volume effect of calcium alginate gel is high. Neurourol. Urodynam. 32: 281–286, 2013. © 2012 Wiley Periodicals, Inc.
Does it work in the long term?—A systematic review on pelvic floor muscle training for female stress urinary incontinence
Authors: Bø Kari , Hilde Gunvor 
Published: July 2012

AbstractAimsThere is level 1, grade A evidence that pelvic floor muscle training (PFMT) is effective in treatment of stress urinary incontinence (SUI), but long‐term outcome has been questioned. The aim of this systematic review was to evaluate the long‐term outcome of PFMT for female SUI.MethodsComputerized search on PubMed up to year 2012 was undertaken with the search strategy: pelvic floor AND (urinary incontinence OR stress urinary incontinence) AND (training OR exercise OR physical activity) AND (follow‐up OR long‐term). Limitations were: humans, female, clinical trial, English, and adults. Inclusion criteria were: studies on SUI using PFMT with or without biofeedback as the intervention, follow‐up period of ≥1 year. Exclusion criteria were studies using electrical stimulation alone and studies in the peripartum period.ResultsNineteen studies were included (1,141 women followed between 1 and 15 years). Statistical meta‐analysis was not performed due to high heterogeneity. Only two studies provided follow‐up interventions. Losses to follow‐up during the long‐term period ranged between 0% and 39%. Long‐term adherence to PFMT varied between 10% and 70%. Five studies reported that the initial success rate on SUI and MUI was maintained at long‐term. Long‐term success based on responders to the original trial varied between 41% and 85%. Surgery rates at long term varied between 4.9% and 58%.ConclusionsShort‐term outcome of PFMT can be maintained at long‐term follow‐up without incentives for continued training, but there is a high heterogeneity in both interventional and methodological quality in short‐and long‐term pelvic floor muscle training studies. Neurourol. Urodynam. 32: 215–223, 2013. © 2012 Wiley Periodicals, Inc.
Clinical features and outcomes in patients with secondary Ewing sarcoma
Authors: Applebaum Mark A. , Goldsby Robert , Neuhaus John , DuBois Steven G. 
Published: July 2012

AbstractBackgroundEwing sarcoma (EWS) is rarely diagnosed as a second malignancy. We sought to describe a cohort of patients with secondary EWS and investigate if patient characteristics and survival differ between patients with secondary and primary EWS.ProcedurePatients with EWS or peripheral primitive neuroectodermal tumor (PNET) reported to the Surveillance, Epidemiology, and End Results Program (SEER) database from 1973 to 2008 were evaluated based on primary or secondary tumor sequence. Overall survival was estimated by Kaplan–Meier methods and evaluated using the log‐rank test. Competing risk analysis was used to describe risk of death due to malignancy rather than other causes.ResultsFifty‐eight cases of secondary EWS were reported, accounting for 2.1% of all EWS cases. The median latency from primary malignancy to secondary EWS was 64 months (range 1–282 months). 12.1% of patients with secondary EWS received radiation to the site of secondary tumor during therapy for their primary malignancy. Patients with secondary EWS were more likely to have axial tumors (77.4% vs. 62.5%; P = 0.03) and smaller tumors (75.0% vs. 48.2% <8 cm; P = 0.001). Five‐year overall survival from diagnosis was inferior for patients with secondary compared to primary EWS (34.3% vs. 52.2%; P = 0.002). However, patients with secondary tumors were less likely than those with primary EWS to die from their malignancy [hazard ratio 0.44; 95% confidence interval (CI) 0.23–0.85].ConclusionsSecondary EWS accounts for a minority of cases of EWS. Tumor size and site and patient survival differ among patients with primary and secondary EWS. Pediatr Blood Cancer 2013; 60: 611–615. © 2012 Wiley Periodicals, Inc.
Optic pathway glioma as part of a constitutional mismatch‐repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1
Authors: Yeung Jacky T. , Pollack Ian F. , Shah Sapana , Jaffe Ronald , Nikiforova Marina , Jakacki Regina I. 
Published: July 2012

AbstractPatients with constitutional mismatch repair‐deficiency (CMMR‐D) caused by the biallelic deletions of mismatch repair (MMR) genes have a high likelihood of developing malignancies of the bone marrow, bowel, and brain. Affected individuals often have phenotypic features of neurofibromatosis type 1 (NF‐1), including café‐au‐lait spots. Optic pathway gliomas (OPGs), a common manifestation of NF‐1, have not been reported. We report the case of a 3‐year‐old male with an extensive OPG who met the diagnostic criteria for NF‐1. He was subsequently found to have multiple colonic polyps and bi‐allelic loss of PMS2. Testing for NF‐1 was negative. Pediatr Blood Cancer 2013; 60: 137–139. © 2012 Wiley Periodicals, Inc.
Psychoactive medication use and neurocognitive function in adult survivors of childhood cancer: A report from the childhood cancer survivor study
Authors: Brinkman Tara M. , Zhang Nan , Ullrich Nicole J. , Brouwers Pim , Green Daniel M. , Srivastava Deo Kumar , Zeltzer Lonnie K. , Stovall Marilyn , Robison Leslie L. , Krull Kevin R. 
Published: July 2012

AbstractBackgroundAdult survivors of childhood cancer are at risk for long‐term morbidities, which may be managed pharmacologically. Psychoactive medication treatment has been associated with adverse effects on specific neurocognitive processes in non‐cancer populations, yet these associations have not been examined in adult survivors of childhood cancer.ProcedureOutcomes were evaluated in 7,080 adult survivors from the Childhood Cancer Survivor Study (CCSS) using a validated self‐report Neurocognitive Questionnaire. Multivariable logistic regression models were used to calculate odds ratios (OR) and 95% confidence intervals (CI) for neurocognitive impairment using demographic and treatment factors and survivors' report of prescription medication use.ResultsControlling for cranial radiation, pain, psychological distress, and stroke/seizure, use of antidepressant medications was associated with impaired task efficiency (OR = 1.80, 95% CI = 1.47–2.21), organization (OR = 1.83, 95% CI = 1.48–2.25), memory (OR = 1.53, 95% CI = 1.27–1.84), and emotional regulation (OR = 2.06, 95% CI = 1.70–2.51). Neuroleptics and stimulants were associated with impaired task efficiency (OR = 2.46, 95% CI = 1.29–4.69; OR = 2.82, 95% CI = 1.61–4.93, respectively) and memory (OR = 2.08, 95% CI = 1.13–3.82; OR = 2.69, 95% CI = 1.59–4.54, respectively). Anticonvulsants were associated with impaired task efficiency, memory, and emotional regulation, although survivors who use these medications may be at risk for neurocognitive impairment on the basis of seizure disorder and/or underlying tumor location (CNS).ConclusionsThese findings suggest that specific psychoactive medications and/or mental health conditions may be associated with neurocognitive function in adult survivors of childhood cancer. The extent to which these associations are causal or indicative of underlying neurological impairment for which the medications are prescribed remains to be ascertained. Pediatr Blood Cancer 2013; 60: 486–493. © 2012 Wiley Periodicals, Inc.
The impact of attention on social functioning in survivors of pediatric acute lymphoblastic leukemia and brain tumors
Authors: Moyer Katherine H. , Willard Victoria W. , Gross Alan M. , Netson Kelli L. , Ashford Jason M. , Kahalley Lisa S. , Wu Shengjie , Xiong Xiaoping , Conklin Heather M. 
Published: July 2012

AbstractBackgroundThe cognitive late effects experienced by many survivors of pediatric acute lymphoblastic leukemia (ALL) and brain tumors are well‐established. The most commonly reported deficit is difficulty with attention. Problems with social functioning have also been identified, but their relationship with cognitive functioning is not well understood. This multi‐site, cross‐sectional study aimed to examine the impact of attention on social functioning.ProcedureFour hundred sixty nine survivors of ALL and brain tumors (55% ALL; 57% male) completed study procedures, including parent‐ and teacher‐report measures of attention (Conners' Rating Scales, Revised) and parent‐report of social functioning [Social Skills Rating System (SSRS)] as part of their screening evaluation for a large clinical trial. Survivors were 12.1 years of age and 4.9 years from the end of treatment at the time of study.ResultsResults revealed that survivors' parent‐reported attention problems were uniquely associated with their social functioning, relative to known demographic‐ and treatment‐related risk factors. Teacher‐reported attention problems, in contrast, were not, despite a significant correlation between the two. Deficits in intelligence and female gender were also significantly associated with poor social functioning.ConclusionsAttention problems uniquely impact difficulties with social functioning in survivors of pediatric cancer. Future studies will need to further examine the relationship between attention and social functioning in survivors, particularly when assessed by teacher report. Pediatr Blood Cancer 2012; 59: 1290–1295. © 2012 Wiley Periodicals, Inc.
Impact of low‐dose involved‐field radiation therapy on pediatric patients with lymphocyte‐predominant Hodgkin lymphoma treated with chemotherapy: A report from the Children's Oncology Group
Authors: Appel Burton E. , Chen Lu , Buxton Allen , Wolden Suzanne L. , Hodgson David C. , Nachman James B. 
Published: July 2012

AbstractBackgroundTreatment of pediatric lymphocyte‐predominant Hodgkin lymphoma (LPHL) is controversial but has typically consisted of both chemotherapy and radiation. Radiation therapy is associated with potential late effects in children and adolescents. We examined the impact of radiation therapy on long‐term outcome of patients with LPHL treated on CCG‐5942, a large pediatric cooperative group study of Hodgkin lymphoma (HL).ProcedureEighty‐two patients with LPHL were registered on CCG‐5942. Fifty‐two patients (63%) received chemotherapy alone; 29 patients (35%) received chemotherapy followed by involved‐field radiation therapy (IFRT).ResultsThe median follow‐up of the LPHL patients is 7.7 years; 63 patients (77%) have >5 years of follow‐up. The 5‐year event‐free survival (EFS) and overall survival (OS) were 97% and 100%. Two relapses occurred, both in patients who did not receive IFRT. There were no significant differences in EFS or OS between patients who received or did not receive IFRT.ConclusionsThis subset analysis demonstrates the chemosensitivity of pediatric LPHL. Patients who had a complete response to chemotherapy had an excellent EFS and OS without the addition of radiotherapy. Pediatr Blood Cancer 2012; 59: 1284–1289. © 2012 Wiley Periodicals, Inc.
Treating Pain With the Lidocaine Patch 5% After Total Knee Arthroplasty
Authors: Khanna Malini , Peters Candice , Singh Jaspal Ricky 
Published: July 2012

ObjectiveTo investigate the potential benefits of the lidocaine patch 5% for pain control during the postoperative period after a total knee arthroplasty (TKA).Design/SettingA prospective cohort study in which we analyzed patients admitted to an inpatient rehabilitation unit after a TKA.ParticipantsFifty‐three consecutive patients who underwent a TKA and were admitted to an orthopedic rehabilitation unit.MethodsThirty‐one patients received the lidocaine patch 5%, and 22 patients served as the control group. On the day of admission, the 24‐item Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used to evaluate each patient's pain and functional capacity before surgery. The Visual Analog Scale (VAS) was used to assess pain ratings every other day starting on rehabilitation day 1. The average end point of the study was rehabilitation day 11.Main Outcome MeasuresThe primary outcome measure was the change in VAS from day of admission. Secondary outcomes in the lidocaine patch 5% group consisted of length of use and a patient satisfaction survey.ResultsThe lidocaine patch 5% and control group were demographically well matched. The average admission WOMAC score was 49.3 and 57.1 for the lidocaine patch 5% and control groups, respectively. The average length of stay was 13.2 ± 5.1 days for the lidocaine patch 5% group and 12.4 ± 3.7 days for the control group. A statistically significant difference in VAS was found on day 3 (P = .05) between the 2 groups, with the control group demonstrating better pain relief. However, both groups reported similar pain improvements by the end of their hospital stay. Of the 31 patients receiving lidocaine patch 5%, 94% of the patients reported satisfaction and attributed pain relief to its use.ConclusionsOverall, the concurrent use of lidocaine patch 5% in treating the postoperative pain of patients after TKA does not provide significant additional pain relief compared with control subjects.
‘THE MODERN SHOPPING EXPERIENCE’: KINGSWAY DEPARTMENT STORE AND CONSUMER POLITICS IN GHANA
Authors: Murillo Bianca 
Published: July 2012

ABSTRACTDespite the perception that department stores are a recent phenomenon in West Africa, modern indoor retail spaces have existed in its major cities since the mid-twentieth century. This article uses the history of Kingsway Department Store in Accra as a lens to understand emerging political, economic and social tensions in post-colonial Ghana. Drawing on United Africa Company (UAC) records, staff reports and inspection findings, as well as local newspapers, advertising and oral interviews, I demonstrate how legacies of colonial capitalism, struggles for political independence and negotiations over what constituted the ‘modern’ fuelled both local and foreign support of the project. For the UAC, investment was an opportunity to legitimize its activities in a newly independent Ghana and a means to shed its image as a colonial merchant firm. While local authorities were divided on whether large-scale retail developments should be part of an expanding post-colonial city, Prime Minister Kwame Nkrumah thought the store might provide a key component in constructing his vision of a new modern nation. However, the presence of white-collar working women, young managers supervising older employees, and the mixing of white expatriate and African shoppers exacerbated social conflicts – challenging local and colonial notions of authority based on race, gender and age.
Prosodic features of bad news and good news in conversation
Authors: Freese Jeremy , Maynard Douglas W. 
Published: July 2012

ABSTRACTRecent work suggests the importance of integrating prosodic research with research on the sequential organization of ordinary conversation. This paper examines how interactants use prosody as a resource in the joint accomplishment of delivered news as good or bad. Analysis of approximately 100 naturally occurring conversational news deliveries reveals that both good and bad news are presented and received with characteristic prosodic features that are consistent with expression of joy and sorrow, respectively, as described in the existing literature on prosody. These prosodic features are systematically deployed in each of the four turns of the prototypical news delivery sequence. Proposals and ratifications of the valence of a delivery are often made prosodically in the initial turns of the prototypical four-turn news delivery, while lexical assessments of news are often made later. When prosody is used to propose the valence of an item of news, subsequent lexical assessments tend to be alignments with these earlier ascriptions of valence, rather than independent appraisals of the news. (Bad news, good news, conversation analysis, prosody, sequencing).
Oh-prefaced responses to inquiry
Authors: Heritage John 
Published: July 2012

ABSTRACTIn responses to English questions, prefacing with the particleohindicates that, from the viewpoint of the answerer, a question is problematic in terms of its relevance, presuppositions, or context. In addition, oh-prefacing is used to foreshadow reluctance to advance the conversational topic invoked by a question; it may also be part of a “trouble-premonitory” response to various types ofHow are youinquiries in conversational openings and elsewhere. (Conversation analysis, English, utterance design, particles.)
Geological framework of the Inner Hebrides
Authors: Bowes D. R. 
Published: July 2012

SynopsisThe geology of the Inner Hebrides covers the time span from ca 2900 m.y. (million years) ago to the present and is dominated by three major crustal regimes. The foreland of the Caledonides is represented by the metamorphic rocks of the Lewisian complex on Rona, Raasay, Coll and Tiree. It is separated by the Moine thrust from the ca 525–100 m.y. old Caledonian mountain chain which is represented by the sediments of the Dalradian Supergroup of Jura and much of Islay. The younger, ca 60 m.y. old, Hebridean Tertiary Igneous Province has major centres in Skye, Rhum and Mull and basaltic lava flows cover considerable areas. Other geological features include the Mesozoic sediments and the products of both the Quaternary glacial activity and present day sedimentation.
Tertiary igneous activity in the Inner Hebrides
Authors: Donaldson Colin H. 
Published: July 2012

SynopsisThe magmatism early in the Tertiary period resulted in (1) eruption of extensive plateau lavas (Skye, Small Isles, Mull) and of Central-Group lavas (Mull, central Arran), and (2) emplacement of central intrusion complexes (Skye, Rhum, Mull, Blackstones Bank, Arran), of sill complexes (northern Skye, Shiant Isles, western Mull, southern Arran) and of dyke swarms (almost all of the Inner Hebrides) focused on the central intrusion complexes. Each of these magmatic stages and the rock types formed are described, with particular emphasis on the central intrusion complexes and the fact that the centres about which intrusion occurred shifted with time. Some of the causes of compositional variation among rock types are briefly discussed. Most of the magmatism occurred between 61 and 58 million years ago when rifting and separation of eastern Greenland and north-western Europe was initiated.
Climate of the Inner Hebrides
Authors: Green F. H. W. , Harding R. J. 
Published: July 2012

SynopsisThe climate of the Inner Hebrides is considered as a variant (a) of the climate of the British Isles, and (b) of the European Atlantic seaboard. Its chief characteristics are wetness, and mildness—expressed as minimal variation of temperature both diurnally and seasonally. Other features are the marked effect of topography, particularly on rainfall, cloudiness, and windiness. The ecological significance of these features is stressed.