bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marine range shifts and species introductions: comparative spread rates and community impacts
Authors: Sorte Cascade J. B. , Williams Susan L. , Carlton James T. 
Published: March 2010

ABSTRACTAim  Shifts in species ranges are a predicted and realized effect of global climate change; however, few studies have addressed the rates and consequence of such shifts, particularly in marine systems. Given ecological similarities between shifting and introduced species, we examined how our understanding of range shifts may be informed by the more established study of non‐native species introductions.Location  Marine systems world‐wide.Methods  Database and citation searches were used to identify 129 marine species experiencing range shifts and to determine spread rates and impacts on recipient communities. Analyses of spread rates were based on studies for which post‐establishment spread was reported in linear distance. The sizes of the effects of community impacts of shifting species were compared with those of functionally similar introduced species having ecologically similar impacts.Results  Our review and meta‐analyses revealed that: (1) 75% of the range shifts found through the database search were in the poleward direction, consistent with climate change scenarios, (2) spread rates of range shifts were lower than those of introductions, (3) shifting species spread over an order of magnitude faster in marine than in terrestrial systems, and (4) directions of community effects were largely negative and magnitudes were often similar for shifters and introduced species; however, this comparison was limited by few data for range‐shifting species.Main conclusions  Although marine range shifts are likely to proceed more slowly than marine introductions, the community‐level effects could be as great, and in the same direction, as those of introduced species. Because it is well‐established that introduced species are a primary threat to global biodiversity, it follows that, just like introductions, range shifts have the potential to seriously affect biological systems. In addition, given that ranges shift faster in marine than terrestrial environments, marine communities might be affected faster than terrestrial ones as species shift with climate change. Regardless of habitat, consideration of range shifts in the context of invasion biology can improve our understanding of what to expect from climate change‐driven shifts as well as provide tools for formal assessment of risks to community structure and function.
The role of non‐native plants and vertebrates in defining patterns of compositional dissimilarity within and across continents
Authors: Winter Marten , Kühn Ingolf , La Sorte Frank A. , Schweiger Oliver , Nentwig Wolfgang , Klotz Stefan 
Published: March 2010

ABSTRACTAim  Human activities have led to the spread and establishment of increasing numbers of non‐native species. Here we assess whether non‐native plant and vertebrate species have affected species compositions within and across Europe and North America. We also assess the effects of intra‐continental species exchange using the example of vertebrates.Location  European countries and North America (states in the contiguous United States and provinces of Canada).Methods  We measured compositional dissimilarity of native and non‐native assemblages of vascular plants and vertebrates and related these patterns to climatic dissimilarity and geographical distance. We considered three categories of non‐native species (introduced after ad 1500), namely: those (1) originating outside of both continents, (2) native to one continent and non‐native to the other, and (3) native in a particular region of a continent but non‐native in another region.Results  The presence of non‐native plants and vertebrates led to more homogeneous species compositions between continents and to less homogeneous species composition within Europe compared with the native assemblages. In North America, the presence of non‐native plants led to more homogeneous species compositions and the presence of non‐native vertebrates had no effect. Species compositions being more homogeneous than the native composition were found for the three categories of non‐native vertebrate species for both continents. Between continents, climate was a better predictor of compositional dissimilarity for non‐native plants, whereas for vertebrates the explanatory power of climate and geographical distance were comparable. By contrast, within continents, climate was a better predictor of compositional dissimilarity of both plants and vertebrates.Conclusions  We found clear evidence for biotic homogenization as a consequence of species displacement. However, in relation to overall species richness this effect was rather small, indicating that floras and faunas are still quite distinct. Therefore, claiming that we already face homogeneous biotas might be premature, although clear indications are visible which should raise a note of caution, especially in the light of increasing globalization.
Negative and atypical story content themes depicted by children with behaviour problems
Authors: Wan Ming Wai , Green Jonathan 
Published: March 2010

Background:  Specific thematic content arising from children’s doll play is often considered to give clinically meaningful information regarding their mental state, but has received little systematic enquiry. This exploratory study examined the negative and atypical content themes in the attachment story narratives of children with behaviour problems, and their associations with child symptomatology and parental depressed mood.Method:  Videotaped mother–child attachment doll play completions of 77 children from a clinical sample were blind coded for negative content themes. Mothers completed questionnaires for maternal depression and child behaviour.Results:  Children rating positive for behaviour disorder were more likely to represent maternal injury, role reversal and marked maternal sadness. Severe behavioural symptoms were associated with more pervasive negative themes. Half of the overall sample depicted child accidents and maternal unresponsiveness, whereas child aggression, child anger and maternal absence were rare. Girls with depressed mothers showed an absence of particular negative representations (e.g., child sadness) compared to boys.Conclusions:  Specific atypical themes are associated with the extent of child psychopathology and may be modified by exposure to maternal depressed mood. The methodological limitations in this exploratory study are also discussed.
LIF‐dependent JAK3 activation is not essential for retinal degeneration
Authors: Lange Christina , Thiersch Markus , Samardzija Marijana , Bürgi Sandra , Joly Sandrine , Grimm Christian 
Published: March 2010

J. Neurochem. (2010) 113, 1210–1220.AbstractRetinal degeneration causes the induction of a leukemia inhibitory factor (LIF)‐controlled survival pathway which includes Janus kinase/signal transducer and activator of transcription signaling. Lack of LIF prevents activation of this signaling cascade and accelerates disease progression leading to a fast loss of photoreceptor cells. In this study, we show that expression of Janus kinase 3 (Jak3), but not of the other members of the family of Janus kinases, is induced in four different models of retinal degeneration and that LIF is essential and sufficient to activate Jak3 gene expression. We also show that the induction of Jak3 and Lif may not depend directly on cell death but rather on the retinal stress during photoreceptor degeneration. However, despite its dependence on LIF, JAK3 is not essential for LIF‐mediated photoreceptor protection or gene expression. Also, absence of JAK3 in knockout mice did not affect immune‐related responses in the degenerating retina. JAK3 may therefore play a different, yet unknown, role in the retinal response to photoreceptor injury.
Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer’s disease
Authors: Chang Kuei‐Hua , De Pablo Yolanda , Lee Hyun‐pil , Lee Hyoung‐gon , Smith Mark A. , Shah Kavita 
Published: March 2010

J. Neurochem. (2010) 113, 1221–1229.AbstractCyclin‐dependent kinase (Cdk) 5 and p38 activities are significantly increased in Alzheimer’s Disease (AD). Both p38 and Cdk5 promote neurodegeneration upon deregulation. However, to date the mechanistic link between Cdk5 and p38 remains unclear. This study presents the first mechanism showing Cdk5 as a major regulator of p38 cascade in neurons and in transgenic mouse model of AD. Using β‐amyloid and glutamate as the neurotoxic stimuli, our results show that deregulated Cdk5 induces p38 activation by increasing reactive oxygen species (ROS) in neuronal cells and in primary cortical neurons. Elimination of ROS inhibits p38 activation, revealing ROS as major stimuli of the p38 cascade. Importantly, Cdk5‐mediated p38 activation increases c‐Jun expression, thereby revealing a mechanistic link between deregulated Cdk5 and c‐Jun level in AD brains. c‐Jun is over‐expressed in AD, and is believed to contribute significantly to neurodegeneration. Based on the proposed mechanism, Cdk5 inhibition is more neuroprotective relative to p38 and c‐Jun, suggesting that Cdk5 is an upstream regulator of neurodegenerative pathways triggered by p38 and a preferable therapeutic target for AD.
Undirected motility of filamentous cyanobacteria produces reticulate mats
Authors: SHEPARD R. N. , SUMNER D. Y. 
Published: March 2010

AbstractThe roles of biology in the morphogenesis of microbial mats and stromatolites remain enigmatic due to the vast array of physical and chemical influences on morphology. However, certain microbial behaviors produce complex morphological features that can be directly attributed to motility patterns. Specifically, laboratory experiments with a strain of the cyanobacteria Pseudanabaena demonstrate that distinctive morphologies arise from the undirected gliding and colliding of filaments. When filamentous cells collide, they align and clump, producing intersecting ridges surrounding areas with low cell density, i.e. reticulate structures. Cell motility is essential for the development of reticulates and associated structures: filaments organize into reticulates faster than cell division and growth, and conditions that inhibit motility also inhibit reticulate formation. Cell density of the inoculum affects the frequency of cell–cell collisions, and thus the time required for biofilm organization into reticulate structures. This also affects the specific geometry of the reticulates. These patterns are propagated into larger structures as cyanobacterial cell numbers increase and cells remain motile. Thus, cell motility is important for templating and maintaining the morphology of these microbial communities, demonstrating a direct link between a microbial behavior and a community morphology. Reticulate geometries have been identified in natural microbial mats as well as in the fossil record, and these structures can be attributed to the motility of filamentous bacteria.
Preservation of Existing Soft‐Tissue Contours in the Transition from a Tooth to an Implant Restoration in the Esthetic Zone Using a Flapless Approach: A Clinical Report
Authors: Koutrach Mohamad , Nimmo Arthur 
Published: March 2010

AbstractTwo‐stage placement of a dental implant is a well‐established method for restoring a missing anterior tooth; however, replacement of an anterior tooth by using two‐stage implant surgery may result in changes in the interdental papilla height and loss of alveolar bone with compromised esthetic results. Alternatively, the use of a one‐stage minimally invasive surgical technique followed by immediate provisionalization may facilitate achievement of esthetic and functional success with minimal discomfort and clinical time. This article presents a clinical case with a single anterior tooth replacement, illustrating ridge preservation with healing, delayed implant placement with immediate provisionalization of the implant to support the soft tissue, and a method of recording the soft‐tissue contour in the final impression to achieve an optimal esthetic result.
Influence of Cusp Inclination on Stress Distribution in Implant‐Supported Prostheses. A Three‐Dimensional Finite Element Analysis
Authors: Falcón‐Antenucci Rosse Mary , Pellizzer Eduardo Piza , De Carvalho Paulo Sergio Perri , Goiato Marcelo Coelho , Noritomi Pedro Yoshito 
Published: March 2010

Abstract Purpose: The aim of this study was to assess the influence of cusp inclination on stress distribution in implant‐supported prostheses by 3D finite element method. Materials and Methods: Three‐dimensional models were created to simulate a mandibular bone section with an implant (3.75 mm diameter × 10 mm length) and crown by means of a 3D scanner and 3D CAD software. A screw‐retained single crown was simulated using three cusp inclinations (10°, 20°, 30°). The 3D models (model 10d, model 20d, and model 30d) were transferred to the finite element program NeiNastran 9.0 to generate a mesh and perform the stress analysis. An oblique load of 200 N was applied on the internal vestibular face of the metal ceramic crown. Results: The results were visualized by means of von Mises stress maps. Maximum stress concentration was located at the point of application. The implant showed higher stress values in model 30d (160.68 MPa). Cortical bone showed higher stress values in model 10d (28.23 MPa). Conclusion: Stresses on the implant and implant/abutment interface increased with increasing cusp inclination, and stresses on the cortical bone decreased with increasing cusp inclination.
Comparison of intradialytic blood pressure variability between conventional thrice‐weekly hemodialysis and short daily hemodialysis
Authors: MURASHIMA Miho , KUMAR Dinesh , DOYLE Alden M. , GLICKMAN Joel D. 
Published: March 2010

AbstractIntradialytic blood pressure (BP) variability may be associated with increased mortality. We examined the effect of short daily hemodialysis (SDHD) on intradialytic BP variability relative to conventional thrice‐weekly HD (CHD). This is a retrospective cohort study. Subjects were those converted from CHD to SDHD (n=12). All intradialytic BPs were collected on the last month of CHD, and on month 6 of SDHD. Absolute predialysis BP level and intradialytic BP variability were defined as the intercept and average residual terms, respectively, from a mixed‐effects linear regression model of time on BP. Dialysis modality was a predictor variable (CHD vs. SDHD). Outcome variables were intradialytic BP variability and hypotension (BP<90/55 mmHg at any time during HD). In addition to a predictor and outcomes, the demographics, estimated dry weight, and ultrafiltration ratio were examined. The median (range) age of the patients was 48 (34–77); all had hypertension, and 4 (33%) had diabetes. By a mixed effects linear regression model, the intradialytic systolic BP variability was 13.2 (quartile range 9.5–14.0) mmHg and 10.0 (8.3–10.9) mmHg for CHD and SDHD, respectively (P<0.006). Intradialytic diastolic BP variability was also significantly reduced (7.7 [6.4–9.2] vs. 6.1 [5.5–6.6] mmHg, P=0.005). Relative to CHD, less hypotension was observed during treatment on SDHD: the odds ratio (95% confidence interval) was 0.36 (0.16–0.81; P=0.008). In this retrospective study, SDHD was associated with less intradialytic BP variability and with fewer episodes of hypotension during treatments. Further studies are necessary to generalize these findings.
Prenatal Stretching Exercise and Autonomic Responses: Preliminary Data and a Model for Reducing Preeclampsia
Authors: Yeo SeonAe 
Published: March 2010

Abstract Purpose: Preeclampsia is a leading cause of perinatal mortality and morbidity, and it increases maternal risk for future cardiovascular disease. The purpose of the study was to explore the relationships among stretching exercise, autonomic cardiac response, and the development of preeclampsia. Design: Secondary data analysis. Methods: Heart rate and pulse pressure were longitudinally examined in this secondary data analysis among women who engaged in stretching exercise daily from 18 weeks of gestation to the end of pregnancy compared with women who did walking exercise daily during the same time period. A total of 124 women were randomized to either stretching (n=60) or walking (n=64) in the parent study. Findings: Heart rates in the stretching group were consistently lower than those in the walking group. Conclusions: Based on the results of this secondary data analyses, a physiologic framework for possible beneficial effects of stretching exercise by enhancing autonomic responses on reducing risks for preeclampsia is proposed and discussed. Clinical Relevance: If the protective effect is established, stretching exercise can be translated into nursing intervention for prenatal care.
Host plant genotype determines bottom‐up effects in an aphid‐parasitoid‐predator system
Authors: Schädler Martin , Brandl Roland , Kempel Anne 
Published: March 2010

AbstractPlant genotypes are known to affect performance of insect herbivores and the community structure of both herbivores and higher trophic levels. Still, only a limited number of studies demonstrate differences in the performance of predators and parasitoids because of plant genotypic effects and most of these focus on gall formers. We designed a greenhouse experiment to investigate the effects of host plant genotype on fitness components in a grass‐aphid‐carnivore system. We used clones of quackgrass [Elytrigia repens (L.) Desv. ex Nevski (Poaceae)], the aphid Rhopalosiphum padi (L.) (Hemiptera: Aphididae), the parasitoid wasp Aphidius colemani (Viereck) (Hymenoptera: Braconidae), and the predatory lacewing Chrysoperla carnea (Stephens) (Neuroptera: Chrysopidae). The number of aphid offspring differed considerably among plant genotypes. These differences were only in part because of differences in the production of biomass among host genotypes. Therefore, genotypes may differ in their nutritional value for phytophages. The number of aphids attacked by the parasitoid also differed among genotypes and aphid numbers only partly accounted for this effect. Moreover, pupal development time of female parasitoids was affected by plant genotype. We found no differences in mortality, body size, or sex ratio of hatching wasps between genotypes of quackgrass. Development time of the larvae and larval weight of the predatory lacewings differed among genotypes, but not weight of pupae and adults. Generally, the proportion of the total variance explained by the plant genotype was smaller for parasitoids and predators than for aphids. Overall, our experiments indicated that the plant genotype affects tri‐trophic interactions, but also that the strength of these effects decreases along the food chain.
A synthesis of laboratory and field studies on the effects of transgenic Bacillus thuringiensis (Bt) maize on non‐target Lepidoptera
Authors: Lang A. , Otto M. 
Published: March 2010

AbstractOne of the major applications of transgenic crops in agriculture are the so‐called Bacillus thuringiensis Berliner (Bt) plants, in particular Bt maizes, which produce insecticidal Cry proteins that target specific orders, such as the Lepidoptera or Coleoptera. We reviewed publications that reported on the direct toxic effects of Bt‐maize and/or Cry proteins of current Bt‐maize events on larvae of non‐target butterflies and moths (Lepidoptera). In total, 20 peer‐reviewed publications were identified, of which 16 papers contributed laboratory‐based data and seven field‐based data. An adverse effect on caterpillars was recorded in 52% of all laboratory‐based and in 21% of all field‐based observations. The variables most often studied and having the highest occurrence of effects were larval survival, body mass, and developmental time. Parameters of the adult stage were under‐represented in the studies. Overall, 11 lepidopteran species were tested. The majority of the studies originated from the USA, with the Monarch butterfly being the most studied, whereas other species and other parts of the world were widely neglected. Laboratory experiments were often run under unrealistic conditions from an ecological point of view. Although the papers we reviewed indicated a potential hazard for Lepidoptera that are exposed to and feed on lepidopteran‐specific Bt‐maize pollen, a general conclusion on the level of risk for butterflies and moths cannot as yet be drawn. A comprehensive risk characterization would require thorough hazard identification, exposure assessment, and impact assessment. However, our review showed that even the basic level of hazard characterization is as yet incomplete. Reasons for this are the still‐limited numbers of publications and concurrent lack of knowledge, the restriction of data to only a few species, the over‐representation of North American species, and the identified limitations of both laboratory and field experiments. The findings of this review suggest that more realistic, ecologically meaningful, and detailed experiments and analyses are crucial to improve the present assessment of Bt‐maize cultivation effects on Lepidoptera.
Relationships between subgingival microbiota and GCF biomarkers in generalized aggressive periodontitis
Authors: Teles Ricardo P. , Gursky Lauren C. , Faveri Marcelo , Rosa Edvaldo A. , Teles Flavia R. F. , Feres Magda , Socransky Sigmund S. , Haffajee Anne D. 
Published: March 2010

Teles RP, Gursky LC, Faveri M, Rosa EA, Teles FRF, Feres M, Socransky SS, Haffajee AD. Relationships between subgingival microbiota and GCF biomarkers in generalized aggressive periodontitis. J Clin Periodontol 2010; 37: 313–323. doi: 10.1111/j.1600‐051X.2010.01534.x. AbstractAim: To examine relationships between subgingival biofilm composition and levels of gingival crevicular fluid (GCF) cytokines in periodontal health and generalized aggressive periodontitis (GAP).Materials and Methods: Periodontal parameters were measured in 25 periodontally healthy and 31 GAP subjects. Subgingival plaque and GCF samples were obtained from 14 sites from each subject. Forty subgingival taxa were quantified using checkerboard DNA–DNA hybridization and the concentrations of eight GCF cytokines were measured using Luminex. Cluster analysis was used to define sites with similar subgingival microbiotas in each clinical group. Significance of differences in clinical, microbiological and immunological parameters among clusters was determined using the Kruskal–Wallis test.Results: GAP subjects had statistically significantly higher GCF levels of interleukin‐1β (IL‐1β) (p<0.001), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) (p<0.01) and IL‐1β/IL‐10 ratio (p<0.001) and higher proportions of Red and Orange complex species than periodontally healthy subjects. There were no statistically significant differences in the mean proportion of cytokines among clusters in the periodontally healthy subjects, while the ratio IL‐1β/IL‐10 (p<0.05) differed significantly among clusters in the aggressive periodontitis group.Conclusions: Different subgingival biofilm profiles are associated with distinct patterns of GCF cytokine expression. Aggressive periodontitis subjects were characterized by a higher IL‐1β/IL‐10 ratio than periodontally healthy subjects, suggesting an imbalance between pro‐ and anti‐inflammatory cytokines in aggressive periodontitis.