bluuebunny/crossref_metadata_2025_split huggingface dataset:
Euthanasia-related strain and coping strategies in animal shelter employees
Authors: Baran Benjamin E. , Allen Joseph A. , Rogelberg Steven G. , Spitzmüller Christiane , DiGiacomo Natalie A. , Webb Jennifer B. , Carter Nathan T. , Clark Olga L. , Teeter Lisa A. , Walker Alan G. 
Published: July 2009

Abstract
Objective—To identify and evaluate coping strategies advocated by experienced animal shelter workers who directly engaged in euthanizing animals.
Design—Cross-sectional study.
Sample Population—Animal shelters across the United States in which euthanasia was conducted (5 to 100 employees/shelter).
Procedures—With the assistance of experts associated with the Humane Society of the United States, the authors identified 88 animal shelters throughout the United States in which animal euthanasia was actively conducted and for which contact information regarding the shelter director was available. Staff at 62 animal shelters agreed to participate in the survey. Survey packets were mailed to the 62 shelter directors, who then distributed them to employees. The survey included questions regarding respondent age, level of education, and role and asked those directly involved in the euthanasia of animals to provide advice on strategies for new euthanasia technicians to deal with the related stress. Employees completed the survey and returned it by mail. Content analysis techniques were used to summarize survey responses.
Results—Coping strategies suggested by 242 euthanasia technicians were summarized into 26 distinct coping recommendations in 8 categories: competence or skills strategies, euthanasia behavioral strategies, cognitive or self-talk strategies, emotional regulation strategies, separation strategies, get-help strategies, seek long-term solution strategies, and withdrawal strategies.
Conclusions and Clinical Relevance—Euthanizing animals is a major stressor for many animal shelter workers. Information regarding the coping strategies identified in this study may be useful for training new euthanasia technicians.
Does diabetes affect the intensity of staining of interstitial cells and neuronal tissue in the bladder, prostate and urethra of rabbits?
Authors: Canda Abdullah , Aktas Safiye , Turna Burak , Cinar Mehtap 
Published: July 2009

Abstract
We compared the intensity of staining of interstitial cells (ICs) and neural tissue in the lower urinary tract of rabbits with diabetes with the intensity in normal subjects. Diabetes was induced by injecting alloxane (65mg/kg) in adult male rabbits. After 3 days, rabbits with a blood glucose level >300 mg/dL were considered to have diabetes. After 8 weeks, the rabbits were killed, and tissue specimens from the bladder, prostate and urethra were obtained. ICs were stained with anti-human CD117 (c-kit) rabbit polyclonal antibody, and neural tissue was stained with synaptophysin. The streptavidin-biotin method was used for immunohistochemical staining. The intensity of c-kit and synaptophysin staining were scored as negative (0), weak (+), moderate (++), and strong (+++). Staining intensity of ICs and neural tissue was assessed and compared in tissues obtained from rabbits with diabetes (n=8) and from control subjects (n=7). Although staining intensity of both ICs and neural tissue was found to be significantly decreased in the bladder tissue of rabbits with diabetes compared to that in the control group (p=0.0001 [ICs] and p=0.021 [neural tissue]), no significant differences in staining intensity of ICs and neural tissue in the urethra and in the prostate was found when rabbits with diabetes were compared to the control group. Diabetes may cause dysfunction of the lower urinary tract, particularly in the urinary bladder, as shown by the staining intensity of ICs and neural tissue.
The value of transabdominal ultrasound for assessment of the severity of liver steatosis as compared to liver biopsy
Authors: Sporea Ioan , Şirli Roxana , Başa Elena , Cornianu Maria , Popescu Alina , Dănilă Mirela , Focşa Mircea 
Published: July 2009

Abstract
The purpose of our paper was to evaluate the performance of ultrasound (US) for assessment of the severity of liver steatosis as compared to a pathological examination, which is presently considered to be the gold standard, in patients that have undergone liver biopsy for various reasons. We performed echo-assisted liver biopsy in 161 patients with chronic hepatitis with the US aspect of “bright liver” with “posterior attenuation”, using modified Menghini needles. Following the US examination, the severity of liver steatosis was estimated as minimal, mild, moderate. or severe according to the Hepburn classification: absent (affecting 0% to 2% of the hepatocytes), minimal (2% to 10%), mild (10% to 30%), moderate (30% to 60%), and severe (more than 60% of the hepatocytes). The results of this study showed that the sensitivity of US for the prediction of histological steatosis of at least moderate severity was 0.64, with 0.77 specificity, 0.55 positive predictive value, and 0.94 negative predictive value. The overall accuracy was 0.75. This study showed that the transabdominal ultrasound evaluation of the fatty liver is a quite good predictor, perhaps sufficient for most purposes, for the estimation of the severity of liver steatosis in the moderate to severe range.
Coronary artery disease associated with radiation therapy
Authors: Celık Turgay , Yuksel Cagdas , Demırkol Sait , Iyısoy Atila , Ulutın Cuneyt 
Published: July 2009

Abstract
Recent advancements in curative-intent therapies have led to dramatic improvements in breast cancer-specific mortality but at the direct expense of increased risk of cardiovascular-related mortality. The use of radiation therapy has led to significant improvements in survival for patients treated for breast cancer. However, as patients live longer, the potentially serious adverse effects of radiation on the heart have raised concerns. Coronary artery disease following irradiation is encountered rarely but is one of the most devastating treatable complications.In this article we review the cardiac complications associated with radiation therapy.
Secondary cold agglutinin disease associated with Hashimoto disease
Authors: Cikrikcioglu Mehmet , Hursitoglu Mehmet , Erkal Hafize , Karaca Nilay , Coraoglu Sati , Tukek Tufan 
Published: July 2009

Abstract
Our case involves a 53 year old woman. Three years ago, she was investigated because of normal hemoglobin levels despite very a low erythrocyte count, which was revealed during the preoperative evaluation for ovarian cyst operation. The Direct Coombs test was found to be positive against complement and negative against IgG. Cold agglutinin titer was 1/448 (+). Due to the polyclonal IgM increase, secondary cold agglutinin disease (CAD) was considered but no factor could be found that would lead to cold agglutinin disease. During the post-operative follow-up, cold agglutinin titers increased with fluctuations in the patient. Twenty-four months after transabdominal hysterectomy and bilateral salpingooopherectomy operation, diagnosis of Hashimoto disease was made upon detection of subclinical hypothyroidism. No case of Hashimoto disease associated with CAD caused by polyclonal IgM has been reported until the present time.
Wing-Tagging Temporarily Affects Time Budgets of Large Gulls
Authors: Bellebaum Jochen , Buchheim Andreas 
Published: July 2009

Wing-Tagging Temporarily Affects Time Budgets of Large Gulls
We studied behaviour of large gulls recently marked with wing-tags at loafing sites at an inland refuse dump using focal birds. During the first 3-4 weeks after marking, wing-tagged gulls spent more time preening at the refuse dump than unmarked birds, which usually did not preen there, while no difference between those two groups was observed at other sites. The possible reasons for preening on the refuse dump are that marked gulls either avoided flying to the loafing water because wing-tags impaired their flight, or showed displacement behaviour.
The role of bracing, casting, and vertical expandable prosthetic titanium rib for the treatment of infantile idiopathic scoliosis: a single-institution experience with 31 consecutive patients
Authors: Smith Jason R. , Samdani Amer F. , Pahys Joshua , Ranade Ashish , Asghar Jahangir , Cahill Patrick , Betz Randal R. 
Published: July 2009

Object
There are few data on treatment results for patients with idiopathic infantile scoliosis (IIS). Thus, the authors have performed a retrospective review of their experience with treating these patients, particularly as newer technologies, such as the vertical expandable prosthetic titanium rib (VEPTR), emerge.

Methods
This retrospective study was conducted to evaluate the methods of treatment used to manage IIS at a single institution. The authors reviewed 31 consecutive patients with a primary diagnosis of IIS. Patients were screened to ensure that there were no confounding congenital anomalies or comorbidities that may have contributed to the spinal deformity. The average age at the time of initial treatment was 25 months. Treatment modalities included bracing, serial body casting, and VEPTR. Pretreatment, posttreatment, and most recent Cobb angles were compared to assess the overall curve correction, and patient charts were reviewed for the occurrence of complications.

Results
Of the 31 patients, 17 were treated with a brace, 9 of whom had curve progression and went on to other forms of treatment. Of the 8 who did respond, there was an overall improvement of 51.2%. The 10 patients who received body casts, who had a mean preoperative Cobb angle of 50.4°, demonstrated an average correction of 59.0%, with only a few skin irritations reported. The 10 patients treated with VEPTR devices demonstrated a mean preoperative Cobb angle of 90.0°, and an average correction of 33.8% was attained. Three of the VEPTR-treated patients (33%) experienced minor problems.

Conclusions
The authors' results suggest that body casting has utility for appropriately selected patients; that is, those with smaller, flexible spinal curves. Bracing had limited utility, with high levels of progression and the need for secondary treatments. The VEPTR device appears to be a viable alternative for large-magnitude curves.
Using lamina screws as a salvage technique at C-7: computed tomography and biomechanical analysis using cadaveric vertebrae
Authors: Cardoso Mario J. , Dmitriev Anton E. , Helgeson Melvin D. , Stephens Frederick , Campbell Victoria , Lehman Ronald A. , Cooper Patrick , Rosner Michael K. 
Published: July 2009

Object
Transpedicular instrumentation at C-7 has been well accepted, but salvage techniques are limited. Lamina screws have been shown to be a biomechanically sound salvage technique in the proximal thoracic spine, but have not been evaluated in the lower cervical spine. The following study evaluates the anatomical feasibility of lamina screws at C-7 as well as their bone-screw interface strength as a salvage technique.

Methods
Nine fresh-frozen C-7 cadaveric specimens were scanned for bone mineral density using dual energy x-ray absorptiometry. Prior to testing, all specimens were imaged using CT to obtain 1-mm axial sections. Caliper measurements of both pedicle width and laminar thickness were obtained. On the right side, pedicle screws were first inserted and then pulled out. Salvage intralaminar screws were inserted into the left lamina from the right spinous process/lamina junction and then pulled out. All screws were placed by experienced cervical spine surgeons under direct fluoroscopic visualization. Pedicle and lamina screws were 4.35- and 3.5-mm in diameter, respectively. Screws sizes were chosen based on direct and radiographic measurements of the respective anatomical regions. Insertional torque (IT) was measured in pounds per inch. Tensile loading to failure was performed in-line with the screw axis at a rate of 0.25 mm/sec using a MiniBionix II system with data recorded in Newtons.

Results
Using lamina screws as a salvage technique generated mean pullout forces (778.9 ± 161.4 N) similar to that of the index pedicle screws (805.3 ± 261.7 N; p = 0.796). However, mean lamina screw peak IT (5.2 ± 2.0 lbs/in) was significantly lower than mean index pedicle screw peak IT (9.1 ± 3.6 lbs/in; p = 0.012). Bone mineral density was strongly correlated with pedicle screw pullout strength (r = 0.95) but less with lamina screw pullout strength (r = 0.04). The mean lamina width measured using calipers (5.7 ± 1.0 mm) was significantly different from the CTmeasured mean lamina width (5.1 ± 0.8 mm; p = 0.003). Similarly, the mean pedicle width recorded with calipers (6.6 ± 1.1 mm) was significantly different from the CT-measured mean pedicle width (6.2 ± 1.3 mm; p = 0.014). The mean laminar width measured on CT at the thinnest point ranged from 3.8 to 6.8 mm, allowing a 3.5-mm screw to be placed without difficulty.

Conclusions
These results suggest that using lamina screws as a salvage technique at C-7 provides similar fixation strength as the index pedicle screw. The C-7 lamina appears to have an ideal anatomical width for the insertion of 3.5-mm screws commonly used for cervical fusions. Therefore, if the transpedicular screw fails, using intralaminar screws appear to be a biomechanically sound salvage technique.
Surgical anatomy and quantitation of the branches of the V2 and V3 segments of the vertebral artery
Authors: Tubbs R. Shane , Shah Nemil A. , Sullivan Brian P. , Marchase Nicholas D. , Cohen-Gadol Aaron A. 
Published: July 2009

Object
The vertebral artery (VA) and its branches may be encountered during various neurosurgical procedures such as far lateral suboccipital approaches to the skull base and spinal operations. Therefore, a working knowledge of the distribution and significance of such VA branches may be advantageous to the surgeon. To date, quantitation of these branches is lacking in the literature.

Methods
The authors evaluated the branches of 20 VAs from 10 adult cadavers and assessed the distribution and surgical significance of the branches from the V2 and V3 segments.

Results
In terms of target tissues, the VA branches encountered at the C1–2 level were most likely to be muscular, branches at C2–3 osseous, and those at C3–6 radicular. No radicular or medullary branches were identified arising from any V3 segment of the VA or C1–2 level of the V2 segment. The greatest concentration of branches per level was found arising from the V2 segment at C2–3. Posterior branches of the VA tended to be radicular or muscular, whereas anterior branches tended to be radicular or osseous. Lateral branches were most commonly radicular and medial branches tended to be osseous or muscular in nature. The largest branches of the VA originated from its V3 segment or the C2–3 part of its V2 segment. Rarely, branches to the extracranial glossopharyngeal and spinal accessory nerves were identified originating from the V3 and V2 segments of the VA, respectively.

Conclusions
Although seemingly diverse in their distribution, the branches of the V2 and V3 segments of the VA may follow a certain consistent arrangement. The potential for injury to neural branches of the VA is minimal at its V3 segment and the C1–2 portion of its V2 segment. Such knowledge may be of use to the neurosurgeon who operates in the neck and at the craniocervical junction.
Human neocortical electrical activity recorded on nonpenetrating microwire arrays: applicability for neuroprostheses
Authors: Kellis Spencer S. , House Paul A. , Thomson Kyle E. , Brown Richard , Greger Bradley 
Published: July 2009

Object
The goal of this study was to determine whether a nonpenetrating, high-density microwire array could provide sufficient information to serve as the interface for decoding motor cortical signals.

Methods
Arrays of nonpenetrating microwires were implanted over the human motor cortex in 2 patients. The patients performed directed stereotypical reaching movements in 2 directions. The resulting data were used to determine whether the reach direction could be distinguished through a frequency power analysis.

Results
Correlation analysis revealed decreasing signal correlation with distance. The gamma-band power during motor planning allowed binary classification of gross directionality in the reaching movements. The degree of power change was correlated to the underlying gyral pattern.

Conclusions
The nonpenetrating microwire platform showed good potential for allowing differentiated signals to be recorded with high spatial fidelity without cortical penetration.
Robust, long-term control of an electrocorticographic brain-computer interface with fixed parameters
Authors: Blakely Tim , Miller Kai J. , Zanos Stavros P. , Rao Rajesh P. N. , Ojemann Jeffrey G. 
Published: July 2009

All previous multiple-day brain-computer interface (BCI) experiments have dynamically adjusted the parameterization between the signals measured from the brain and the features used to control the interface. The authors present the results of a multiple-day electrocorticographic (ECoG) BCI experiment.
A patient with a subdural electrode array implanted for seizure localization performed tongue motor tasks. After an initial screening and feature selection on the 1st day, 5 consecutive days of cursor-based feedback were performed with a fixed parameterization. Control of the interface was robust throughout all days, with performance increasing to a stable state in which high-frequency ECoG signal could immediately be translated into cursor control.
These findings demonstrate that ECoG-based BCIs can be implemented for multiple-day control without the necessity for sophisticated retraining and adaptation.
Microscale recording from human motor cortex: implications for minimally invasive electrocorticographic brain-computer interfaces
Authors: Leuthardt Eric C. , Freudenberg Zac , Bundy David , Roland Jarod 
Published: July 2009

Object
There is a growing interest in the use of recording from the surface of the brain, known as electrocorticography (ECoG), as a practical signal platform for brain-computer interface application. The signal has a combination of high signal quality and long-term stability that may be the ideal intermediate modality for future application. The research paradigm for studying ECoG signals uses patients requiring invasive monitoring for seizure localization. The implanted arrays span cortex areas on the order of centimeters. Currently, it is unknown what level of motor information can be discerned from small regions of human cortex with microscale ECoG recording.

Methods
In this study, a patient requiring invasive monitoring for seizure localization underwent concurrent implantation with a 16-microwire array (1-mm electrode spacing) placed over primary motor cortex. Microscale activity was recorded while the patient performed simple contra- and ipsilateral wrist movements that were monitored in parallel with electromyography. Using various statistical methods, linear and nonlinear relationships between these microcortical changes and recorded electromyography activity were defined.

Results
Small regions of primary motor cortex (< 5 mm) carry sufficient information to separate multiple aspects of motor movements (that is, wrist flexion/extension and ipsilateral/contralateral movements).

Conclusions
These findings support the conclusion that small regions of cortex investigated by ECoG recording may provide sufficient information about motor intentions to support brain-computer interface operations in the future. Given the small scale of the cortical region required, the requisite implanted array would be minimally invasive in terms of surgical placement of the electrode array.
Increased Frequency of Gastrointestinal Symptoms in Patients with Fibromyalgia and Associated Factors: A Comparative Study
Authors: PAMUK ÖMER NURI , ÜMIT HASAN , HARMANDAR ORBAY 
Published: July 2009

Objective.To determine the frequency and severity of gastrointestinal (GI) symptoms in patients with fibromyalgia (FM).Methods.We included 152 women with FM (mean age 45.4 ± 12.2 yrs), 98 women with rheumatoid arthritis (RA; mean age 45.5 ± 12.3 yrs), and 60 healthy female controls (mean age 44 ± 11.3 yrs). All patients were questioned about the severity of their chronic widespread pain, symptoms of FM, symptoms of dyspepsia, using a visual analog scale (VAS), and anxiety-depression scale. Patients were asked self-reported (yes/no), symptom-based (≥ 2 criteria) constipation and severity of constipation questions, and about the severity of quality of life (QOL) disturbance secondary to dyspepsia and constipation.Results.Patients with FM had higher symptom severities for belching, reflux, bloating, sour taste, and vomiting than patients with RA and controls (all p values < 0.01). Patients with FM had significantly more dyspepsia-related QOL disturbances than the other 2 groups (p < 0.01). FM and RA patients had more frequent self-reported constipation than controls (respectively, 42.1%, 48%, 21.7%; p < 0.01). The frequency of symptom-based constipation was significantly higher in the RA group (49%) than in FM (29.6%) and control groups (23.3%) (p < 0.01). Constipation-related QOL disturbance was significantly higher in patients with FM than in controls (p < 0.01).Conclusion.In patients with FM, the severity scores of dyspepsia symptoms, constipation, and dyspepsia-related QOL disturbance were higher than in patients with RA and controls. The higher GI symptom severity in patients with FM might have negative effects on their QOL.
Measuring episodic memory: A novel approach with an indefinite number of alternative forms
Authors: Humphreys Michael S. , Smith Simon , Pachana Nancy A. , Tehan Gerry , Byrne Gerard J. 
Published: July 2009

AbstractBoth clinical practice and clinical research settings can require successive administrations of a memory test, particularly when following the trajectory of suspected memory decline in older adults. However, relatively few verbal episodic memory tests have alternative forms. We set out to create a broad‐based memory test to allow for the use of an essentially unlimited number of alternative forms. Four tasks for inclusion in such a test were developed. These tasks varied the requirement for recall as opposed to recognition, the need to form an association between unrelated words, and the need to discriminate the most recent list from earlier lists, all of which proved useful. A total of 115 participants completed the battery of tests and were used to show that the test could differentiate between older and younger adults; a sub‐sample of 73 participants completed alternative forms of the tests to determine test–retest reliability and the amount of learning to learn. Copyright © 2009 John Wiley & Sons, Ltd.