bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between cleaning frequency and pressure ulcer healing time in older people receiving home care
Authors: Yoshikawa Yoshiyuki , Maeshige Noriaki , Tanaka Masayuki , Uemura Mikiko , Hiramatsu Terutaka , Fujino Hidemi , Sugimoto Masaharu , Terashi Hiroto 
Published: June 2024

Objective: The relationship between the healing time of pressure ulcers (PUs) and wound cleaning frequency among older people in homecare settings was investigated. Method: This single-centre, prospective cohort study was conducted from April 2018 to March 2019. Patients who used home-visit nursing services, had National Pressure Ulcer Advisory Panel classification stage 2 PUs, and had their wounds cleaned at least twice a week were enrolled in the study. Wound cleaning was performed using tap water and a weakly acidic cleanser. Participants were divided into two groups, determined by the frequency of wound cleaning (twice weekly versus ≥3 times weekly). Duration of PU healing and the increase in care insurance premiums were compared in both groups. Results: A total of 12 patients were included in the study. The mean healing period of PUs cleaned ≥3 times per week (65.3±24.8 days) was significantly shorter than that of PUs cleaned twice a week (102.6±19.2 days; p<0.05). Furthermore, the increase in care insurance premiums for PUs cleaned ≥3 times per week (¥122,497±105,660 Yen per six months) was significantly lower than that for PUs cleaned twice a week (¥238,116±60,428 per six months) (p<0.05). Conclusion: Our results suggest that frequent cleaning of PUs by health professionals in homecare settings not only shorten PU healing period but also reduces care insurance premiums for PU care.
Ten recommendations for hosting a Diversity, Equity, Inclusion, and Justice (DEIJ) journal club
Authors: Díaz Roberto Efraín , Wankowicz Stephanie A. 
Published: June 2024

Despite advances and social progress, the exclusion of diverse groups in academia, especially science, technology, engineering, and mathematics (STEM) fields, across the US and Europe persists, resulting in the underrepresentation of diverse people in higher education. There is extensive literature about theory, observation, and evidence-based practices that can help create a more equitable, inclusive, and diverse learning environment. In this article, we propose the implementation of a Diversity, Equity, Inclusion, and Justice (DEIJ) journal club as a strategic initiative to foster education and promote action towards making academia a more equitable institution. By creating a space for people to engage with DEIJ theories* and strategize ways to improve their learning environment, we hope to normalize the practice and importance of analyzing academia through an equity lens. Guided by restorative justice principles, we offer 10 recommendations for fostering community cohesion through education and mutual understanding. This approach underscores the importance of appropriate action and self-education in the journey toward a more diverse, equitable, inclusive, and just academic environment.
*Authors’ note: We understand that “DEIJ” is a multidisciplinary organizational framework that relies on numerous fields of study, including history, sociology, philosophy, and more. We use this term to refer to these different fields of study for brevity purposes.
Solid dispersion systems for enhanced dissolution of poorly water-soluble candesartan cilexetil: In vitro evaluation and simulated pharmacokinetics studies
Authors: Ali Israa Saad Mustafa , Sajad Uday Aziz , Abdul Rasool Bazigha K. 
Published: June 2024

Background
Candesartan cilexetil (CC) is a selective angiotensin II receptor antagonist widely used to treat hypertension. CC is a substrate of P-glycoprotein (P-gp), causing its efflux to the intestinal lumen. It is also practically insoluble in water and has low oral bioavailability (14%). Thus, the current study aims to improve the in vitro dissolution of CC by developing solid dispersion systems (SDSs) and corroborating the in vitro results using a simulated pharmacokinetics study.

Methods
The SDSs were prepared using polyvinyl pyrrolidone (PVP) as a water-soluble polymer, Eudragit E100 (EE100) as a pH-dependent soluble carrier, and a combination of these two polymers. The saturation solubility and the dissolution rate studies of the prepared systems in three dissolution media were performed. The optimized system SE-EE5 was selected for further investigations, including DSC, XRD, FTIR, FESEM, DLS, TSEM, IVIVC convolution study, and stability studies.

Results
The solubility of CC significantly increased by a factor of 27,037.344 when formulated as a solid dispersion matrix using EE100 at a ratio of 1:5 (w/w) drug to polymer (SE-EE5 SD), compared to the solubility of the pure drug. The mechanism of solubility and dissolution rate enhancement of CC by the optimized SDS was found to be via the conversion of the crystalline CC into the amorphous form as well as nanoparticles formation upon dissolution at a pH below 5. The instrumental analysis tests showed good compatibility between CC and EE100 and there was no chemical interaction between the drug and the polymer. Moreover, the stability tests confirmed that the optimized system was stable after three months of storage at 25°C.

Conclusion
The utilization of the solid dispersion technique employing EE 100 polymer as a matrix demonstrates significant success in enhancing the solubility, dissolution, and subsequently, the bioavailability of water-insoluble drugs like CC.
Differences in referral path, clinical and radiographic outcomes between seronegative and seropositive rheumatoid arthritis Mexican Mestizo patients: A cohort study
Authors: Guaracha-Basáñez Guillermo Arturo , Contreras-Yáñez Irazú , Ortiz-Haro Ana Belén , Pascual-Ramos Virginia 
Published: June 2024

Background
The study compared the referral path, the first two-year clinical outcomes, and the first five-year radiographic outcomes between seronegative patients (SNPs) from a recent-onset rheumatoid arthritis dynamic cohort initiated in 2004 and seropositive patients (SPPs). Predictors of incidental erosive disease were investigated.

Patients and methods
Up to March 2023, one independent observer reviewed the charts from 188 patients with at least two years of clinical assessments and up to five years of annual radiographic assessments. SNPs were defined when baseline RF and ACPA serum titers were within local normal ranges. The erosive disease was defined on hand and/or foot radiographs when at least one unequivocal cortical bone defect was detected. The incidental erosive disease was defined in baseline erosive disease-free patients who developed erosions at follow-ups. Multivariate Cox regression analyses identified hazard ratios (95% confidence interval) for factors to predict incidental erosive disease.

Results
There were 17 (9%) SNPs, and they had a shorter time from symptoms onset to first physician evaluation, visited a lower number of physicians, and received less intensive treatment at referral and during the first years of follow-up than SPPs. Also, they had fewer 0–66 swollen joints and were less frequently persistent on therapy. The erosive disease was detected only in SPPs, and its frequency increased from 10.1% at baseline to 36.1% at the five-year radiographic assessment. There were 53 (31.4%) patients with incidental erosive disease, and differences between SPPs and SNPs were statistically significant at the feet location. Incidental erosive disease was predicted by baseline ACPA, ESR, substantial morning stiffness, and cumulative CRP.

Conclusions
SNPs showed mild differences in their referral path and clinical outcomes compared to SPPs. However, erosive disease was detected only in SPPs and was predicted by baseline and cumulative clinical and serologic variables.
Viral load non-suppression status among women exposed to Dolutegravir-based versus Efavirenz-based regimens in Ethiopia: A before-and-after study
Authors: Facha Wolde , Tadesse Takele , Wolka Eskinder , Astatkie Ayalew 
Published: June 2024

Background
High viral load during pregnancy and breastfeeding period is the risk factor for vertical transmission of human immunodeficiency virus (HIV). Currently, Dolutegravir (DTG)-based regimens are recommended to attain adequate viral load suppression (VLS) among women. However, its effect on VLS has not been investigated among women in PMTCT care in Ethiopia.

Objective
This study aimed to investigate the rate of viral load non-suppression among women exposed to DTG-based versus Efavirenz (EFV)-based regimens in Ethiopia.

Methods
An uncontrolled before-and-after study design was conducted among 924 women (462 on EFV-based and 462 on DTG-based regimens) enrolled in PMTCT care from September 2015 to February 2023. The outcome variable was the viral load (VL) non-suppression among women on PMTCT care. A modified Poisson regression model was employed, and the proportion was computed to compare the rate of VL non-suppression in both groups. The risk ratio (RR) with a 95% confidence interval (CI) was calculated to assess viral load non-suppression among women on DTG-based and EFV-based regimens by adjusting for other variables.

Results
The overall rate of non-suppressed VL was 16.2% (95% CI: 14.0–18.8%). Mothers on DTG-based regimens had approximately a 30% (adjusted risk ratio (aRR): 0.70; 95% CI: 0.52–0.94) lesser risk of developing non-suppressed VL than women on EFV-based regimens. Besides, older women were 1.38 times (aRR: 1.38; 95% CI: 1.04–1.83); mothers who did not disclose their HIV status to their partners were 2.54 times (aRR: 2.54; 95% CI: 1.91–3.38); and mothers who had poor or fair adherence to antiretroviral (ARV) drugs were 2.11 times (aRR: 2.11; 95% CI: 1.45–3.07) at higher risk of non-suppressed VL.

Conclusion
Women on DTG-based regimens had a significantly suppressed VL compared to those on EFV-based regimens. Thus, administering DTG-based first-line ART regimens should be strengthened to achieve global and national targets on VLS.
Beyond the Deck: Critical Essays on Magic: The Gathering and Its Influence, Shelly Jones (ed.) (2023)
Authors: Berge PS 
Published: June 2024

Review of: Beyond the Deck: Critical Essays on Magic: The Gathering and Its Influence, Shelly Jones (ed.) (2023)
Jefferson, NC: McFarland, 301 pp.,
ISBN 978-1-47668-316-4, $39.95
Sommerstück: On Christa Wolf’s Rediscovery of the Idyll
Authors: Beizaei Baharak 
Published: June 2024

Abstract
This article examines Christa Wolf's Sommerstück (1989) through the lens of modernist utopian thinking and genre-theory. The novel challenges the common-sense definition of utopia as an imagined paradisiacal state and the idyll as an idealized vision of communal harmony, complicating the question of dwelling within a utopian idyll at the specific historical conjuncture that preceded the Mauerfall. Interrogating the function of fantasy and the structure of mirage in idealized moments of crystallization with reference to Jameson’s opposition of idyll to utopia, the article contends that utopian impulses in Sommerstück aim to replace the harsh reality of East Germany through the idealization of the quotidian. Although lampooned by Hegel in the Aesthetics as lacking development and the many-sidedness of human interests evinced in epic poetry, the idyll is nonetheless positioned as the prosaic ground for romance and on a continuum with hybrid forms of epic. The article charts the temporal structure of development and progression inherent in the formalism of the genre in terms of the temporal structure of utopian striving. I first identify the temporal structure of idyll and utopia as outlined in the narrative. Of paramount importance is how the narrative, despite being rooted in a specific historical context, attempts to create a utopian vision of social relations as at once timeless and evolving. The shifting relationship between utopian ideals and a changing political reality becomes a focal point for thinking the inseparability of the idyllic from the utopian. With the fall of the Berlin Wall, anti-utopian elements of the negative ideal – the remnants of the old society of control and surveillance – were rendered more prominent to the observers of the divide. From a certain vantage point, then, one could say that the phenomenon of utopia is one of perspectival and spectatorial distance; it intersects with the idyllic mirage of a harmonious collocation in a state of innocence where different societal ideals and classes merge into indistinction. The article deepens the analysis of utopia by considering it within broader frameworks of genre-theory and German idealist thinking, suggesting that the quest for a perfect society may involve control, assimilation, and power struggles – dystopian themes highlighted by the novel when reread in light of catastrophe and a critical reevaluation of the meaning of dwelling at ‘the end of history.’
Nochmals zum Runenwort urnordisch

rūnō-
Authors: Schulte Michael 
Published: June 2024

Abstract
The discovery of a stone fragment from Svingerud/Hole in Norway, whose inscription is dated between 1/25 and 250 CE, attests to the early use of rūnō (cf. Zilmer/Vasshus 2023) as opposed to rūnōʀ. The plural rūnōʀ (ON rúnar) is attested on runestones of the Classical and Post-classical runic periods including C-bracteates. The paper aims to clarify whether rūnō is to be understood soberly with Morris (1985) and Antonsen (1980) as a term of everyday language ›message, inscription‹ to be distinguished from Goth. rūna ›mystery, secret, counsel‹, or rather as a term for ›secret, orally presented knowledge‹, before being linked up to the fuþark and writing in runes in the due course of its history.
Jordan left derivations in infinite matrix rings
Authors: Zhang Daochang , Ma Leiming , Hu Jianping , Sun Chaochao 
Published: June 2024

Abstract
Let

R

R

be a unital associative ring. Our motivation is to prove that left derivations in column finite matrix rings over

R

R

are equal to zero and demonstrate that a left derivation

d
:
T
→
T

d:{\mathcal{T}}\to {\mathcal{T}}

in the infinite upper triangular matrix ring

T

{\mathcal{T}}

is determined by left derivations

d

j

{d}_{j}

in

R

(

j
=
1
,
2
,

…

)

R\left(j=1,2,\ldots )

satisfying

d

(

(

a

i
j

)

)

=

(

b

i
j

)

d\left(\left({a}_{ij}))=\left({b}_{ij})

for any

(

a

i
j

)

∈
T

\left({a}_{ij})\in {\mathcal{T}}

, where

b

i
j

=

d

j

(

a

11

)

,

i
=
1
,

0
,

i
≠
1
.

{b}_{ij}=\left\{\begin{array}{ll}{d}_{j}\left({a}_{11}),& i=1,\\ 0,& i\ne 1.\end{array}\right.

The similar results about Jordan left derivations are also obtained when

R

R

is 2-torsion free.
Evaluation of High-Temperature Rheological and Aging Characteristics in Asphalt Binders Modified with Recycled High-Density Polyethylene and Recycled Polypropylene
Authors: Oyelere Abeeb , Wu Shenghua , Rodriguez Eddie 
Published: June 2024

Abstract
Because of extreme global temperatures driven by climate change, the vulnerability of asphalt pavement to heat-induced damage has become a major concern given increasing traffic loads. Traditional asphalt binders oftentimes do not meet the demanding standards for withstanding this condition. As a result, the use of recycled plastics in asphalt road construction has gained popularity because of its potential performance improvement, sustainability, and cost-effectiveness. This study investigates the impact of recycled high-density polyethylene (rHDPE) and recycled polypropylene (rPP) on the high-temperature rheological properties of asphalt binder throughout its service life. A comprehensive evaluation was conducted to assess the rutting resistance, elastic response, deformability, stress sensitivity, and aging susceptibility of modified binders at high temperature. The findings reveal that the addition of rHDPE and rPP to asphalt binders enhances rutting resistance, as evidenced by improved rutting parameters and rutting failure temperatures. The analysis of nonrecoverable creep compliance and percent recovery also showed improvement in elasticity and resistance to permanent deformation of the modified asphalt. Although rHDPE and rPP-modified asphalt did not meet the criteria for elastomeric polymers, a trend toward improved elastic response was observed with aging. Additionally, the result of the aging index showed that though increased stiffness is observed as asphalt-aged, rPP-modified asphalt is more susceptible to short-term aging but exhibits more stable performance during service life compared with the rHDPE-modified asphalt.
Usos de la cuantificación y categoría de modelación. Una transversalidad de conocimiento matemático
Authors: Gaete-Peralta Claudio , Cordero Francisco , Huincahue Jaime , Mena Jaime 
Published: June 2024

[Objective] The teaching of quantification tends to focus on formulas for quantifying the measurement of geometric magnitudes, ignoring their uses in other disciplines. This makes it essential to formulate reference frameworks that allow such teaching to meet the functional justifications demanded by other domains of knowledge. For this reason, and within the framework of socioepistemology, the aim of this research was to formulate an epistemology of the uses of quantification. [Methodology] The methodology was qualitative and consisted of a theoretical-methodological corpus that articulated constructs of a modelling category with empirical data. This formulation was carried out in two phases. In the first one, an epistemology was hypothetically formulated based on an analysis of resignification of the uses of quantification constructed in two specific measurement situations: one specific to an interdisciplinary community, and the other to the mathematical work entitled Intégrale, Longueur, Aire. The second phase analyzed the emergence of a resignification of the uses of quantification by engineering students during the development of a school situation designed on the basis of hypothetical epistemology. [Results] This emergence made it possible to empirically validate this epistemology and to express a transversality of uses of quantification in specific measurement situations, made up of meanings, procedures and instruments that together can be used to derive quantification arguments. [Conclusions] This epistemology of uses makes it possible to capture the measurement situation as an educational reference to establish the use, resignification, and transversality of quantification.
MODERN LINES IN GEOCHEMISTRY: ANNIVERSARY CONFERENCE
Authors: ВОРОНЦОВ А.А. , КУЗЬМИН М.И. , ПЕРЕПЕЛОВ А.Б. , ШАЦКИЙ В.С. 
Published: June 2024

21—25 ноября 2022 г. Институт геохимии им. А.П. Виноградова Сибирского отделения Российской академии наук организовал и провел юбилейную Всероссийскую конференцию, посвященную 65-летию со дня своего основания и 105-летию со дня рождения его директора академика Льва Владимировича Таусона, руководившего институтом в период с 1961 по 1989 гг. На конференции были представлены результаты исследований, которые связаны с широким кругом вопросов современной геохимии, включая следующие направления: «Изотопно-геохимические исследования магматических, метаморфических и осадочных комплексов пород различных геодинамических обстановок»; «Геохимические исследования рудно-магматических систем и современные методы поисков и прогнозирования месторождений полезных ископаемых»; «Геохимия окружающей среды, геоэкология и палеоклимат»; «Экспериментальное и физико-химическое моделирование природных и техногенных процессов, физическое материаловедение»; «Современные аналитические методы исследований и информационные технологии в науках о Земле». В вводной статье показана неразрывная связь творческого пути Льва Владимировича с развитием Института геохимии СО РАН и приведен обзор материалов, представленных на конференции и затрагивющих ряд проблем формирования геологических комплексов разной природы, включая оценку источников вещества, геодинамических условий их проявления и характеристику рудообразующих процессов
On 21–25 November, 2022, Vinogradov Institute of Geochemistry, Siberian Branch of the Russian Academy of Sciences (Irkutsk), organized an All-Russian anniversary conference celebrating 65 years to the date of the Institute foundation and 105 years to the birth of its first director, Lev Vladimirovich Tauson, Full Member of the Russian Academy of Sciences. The results reported at the conference encompass a wide range of research fields in modern geochemistry, including isotope geochemistry of igneous, metamorphic, and sedimentary rocks in various geodynamic settings; chemistry of ore-magmatic systems and modern methods of mineral exploration; environmental geochemistry, geoecology, and paleoclimate; laboratory modeling and thermodynamic calculations of natural and production-related processes and materials; advanced analytical methods and information technologies for geosciences. The conference presentations pay tribute to Lev Tauson whose academic carrier, as well as all creative activity, had been closely related with the development of the Institute of Geochemistry. The preface paper provides a review of topics discussed at the conference concerning various geodynamic and geochemical problems, including sources of material, petrogenesis, and metallogeny.
Hubungan Pengetahuan dan Sikap Terhadap Perilaku Pencegahan Penularan Tuberkulosis pada Penderita TB di Fasilitas Pelayanan Tingkat Pertama
Authors: Ramadhani Asri , Aristi Dela 
Published: June 2024

Tuberculosis (TB) transmission prevention behavior is an effort to break the chain of transmission of TB disease to people around, especially family members. Knowledge and attitudes of TB sufferers related to TB disease will influence their preventive behavior. The purpose of this study was to determine the relationship between knowledge and attitudes with the behavior of preventing TB transmission in TB patients in the working area of the Wanasari Public Health Center, Brebes Regency. This study used a cross-sectional study design involving 62 respondents. The results showed that the respondents had poor tuberculosis transmission prevention behavior (62.9%). Knowledge (p-value = 0.127) is not related to the behavior of preventing TB transmission, but there is a relationship between attitude (p-value = 0.012) and the behavior of preventing TB transmission. Public health centers are recommended to conduct health counseling for TB patients as an effort to improve attitudes and for TB patients it is important to carry out TB prevention behaviors such as coughing and sneezing etiquette, opening the windows of the house every day, separating eating utensils from other family members, drying mattresses and pillows a week. once, and bask in the sun every day.Keywords: TB transmission prevention behavior, Knowledge, AttitudeAbstrakPerilaku pencegahan penularan Tuberkulosis (TB) merupakan upaya untuk memutus rantai penularan penyakit TB kepada orang-orang sekitar terutama anggota keluarga. Pengetahuan dan sikap penderita TB terkait penyakit TB akan mempengaruhi dalam melakukan perilaku pencegahan. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan dan sikap dengan perilaku pencegahan penularan TB pada penderita TB di wilayah kerja Puskesmas Wanasari Kabupaten Brebes. Penelitian ini menggunakan desain studi cross-sectional dengan melibatkan responden yang berjumlah 62 orang. Hasil penelitian menunjukkan bahawa responden memiliki perilaku pencegahan penularan tuberkulosis yang buruk (62,9%). Pengetahuan (pvalue = 0,127) tidak berhubungan dengan perilaku pencegahan penularan TB namun terdapat hubungan antara sikap (pvalue = 0,012) dengan perilaku pencegahan penularan TB. Puskesmas dianjurkan untuk melakukan konseling kesehatan kepada penderita TB sebagai upaya untuk meningkatkan sikap dan bagi penderita TB penting untuk melakukan perilaku pencegahan TB seperti melakukan etika batuk dan bersin, membuka jendela rumah setiap hari, memisahkan alat makan dengan anggota keluarga lainnya, menjemur kasur dan bantal seminggu sekali, dan berjemur di bawah sinar matahari setiap hari. Kata Kunci: Perilaku Pencegahan Penularan TB, Pengetahuan, Sikap