bluuebunny/crossref_metadata_2025_split huggingface dataset:
980-P: Automated Insulin Delivery Clamp Technology—Proof of Concept Study
Authors: HAWKE KATE , KHAN NABEEL , FOURNIER MARC G. , ELLIOTT TOM 
Published: June 2024

Introduction & Objective: Interventions designed to improve endogenous insulin production and/or reduce exogenous insulin requirements are currently assessed using C-peptide measurement & traditional clamp techniques. We propose a novel adjunctive protocol for determining insulin requirements using Automated Insulin Delivery (AID) systems, known as AID-Clamp.
Methods: With AID-Clamp (see video https://bit.ly/AIDClamp), an individual’s insulin requirement over a defined period is quantified using analysis of the AID event log. An insulin quantification script retrieves basal and bolus insulin data over the time period and provides an output of total insulin requirement.
A 55-year-old man with type 1 diabetes already using AID (open-source iAPS) opted to commence off-label tirzepatide as adjunct therapy. He reported a profound reduction in insulin requirement. We applied AID-Clamp analytics retrospectively to identical meals eaten regularly by this patient, to demonstrate its application.
Results: In the two weeks prior to tirzepatide commencement, mean insulin total daily dose was 194 units. The AID-Clamp 6-hour insulin requirement post standard-meal of 88g carbohydrate was 30.5 units. In the third week of tirzepatide use (dose 5 mg weekly), the mean insulin total daily dose was 113.4 units. The 6-hour insulin requirement post standard 88 g meal was 11.8 units.
Conclusion: AID-Clamp is a novel application for AID systems. When used in appropriate clinical or research settings, it is capable of detailed quantification of insulin requirements. The changes in insulin requirement in response to pharmacologic, lifestyle or other interventions, serve as a proxy for the effect of the intervention. AID-Clamp is non-invasive, carries no additional cost and is much quicker and less labor-intensive than traditional methods of assessing the efficacy of such interventions.

Disclosure
K. Hawke: None. N. Khan: None. M.G. Fournier: None. T. Elliott: Research Support; Biomea Fusion, Inc., Eli Lilly and Company, Novo Nordisk, GlaxoSmithKline plc, Sanofi, Janssen Pharmaceuticals, Inc. Consultant; Vertex Pharmaceuticals Incorporated, Abbott, Dexcom, Inc. Research Support; Zucara Therapeutics.
981-P: Development of a Diabetes Navigator Toolkit to Support Diabetes Technology Uptake and Sustained Use—IMPACT Toolkit
Authors: WOLF RISA M. , ALVER DEFNE , PAN BERNARD , PARIMI NEHA , KLOPOUH MILANA S. , LIU THALIA D. , LIU ABBY D. , SIDHAYE ANIKET , RIEKERT KRISTIN , MATHIOUDAKIS NESTORAS N. 
Published: June 2024

Advanced diabetes technologies (ADT), including continuous glucose monitors (CGMs), insulin pumps, and automated insulin delivery systems, improve glycemic control in Type 1 diabetes. However, these technologies are underutilized, particularly in minority and underserved populations. Barriers to ADT use are well described, yet there are limited reports of solutions to improve ADT uptake. This qualitative interview study of diabetes stakeholders aimed to develop a diabetes toolkit to help improve the uptake and sustained use of ADT.
Semi-structured interviews were conducted, specifically focusing on CGM prescription, CGM education and use, pump prescription, and pump education and use. Rapid qualitative method was employed for efficient data collection and analysis. Key themes were identified and iteratively applied to refine the toolkit.
The participants included 18 providers, 10 community/commercial partners and vendors, and 23 patients/caregivers, among whom 9 used both CGM and pump, 10 used only CGM, and 4 did not use either device. Key barriers included communication lapses, insurance/cost challenges, inadequate education, technological issues, complex processes, and limited resource accessibility. For communication gaps and clinic portal connections, appointing a central liaison such as a diabetes navigator was proposed. Solutions for insurance/cost challenges involved providing transparent cost information. Education enhancements emphasized hands-on training, and providing clear device instructions. In general stakeholders supported adopting the diabetes toolkit for improved technology uptake and use.
A diabetes toolkit could be utilized by a diabetes navigator or another diabetes care team member to help improve the uptake and sustained use of diabetes technologies despite the complex processes involved.

Disclosure
R.M. Wolf: Research Support; Dexcom, Inc., Boehringer-Ingelheim, Novo Nordisk. D. Alver: None. B. Pan: None. N. Parimi: None. M.S. Klopouh: None. T.D. Liu: None. A.D. Liu: None. A. Sidhaye: None. K. Riekert: Consultant; Vertex Pharmaceuticals Incorporated. N.N. Mathioudakis: None.

Funding
NIDDK (1R01DK134955-01)
Pembuatan Sabun Facial Wash Berbasis Minyak Kelapa Murni (Virgin Coconut Oil) dengan Penambahan Ekstrak Kulit Pisang Ambon (Musa Parisidiaca L.) Sebagai Anti Hiperpigmentasi
Authors: Dini Hanny Sekar , Fuadi Ahmad M. 
Published: June 2024

Sabun facial wash adalah salah satu jenis sabun yang memiliki fungsi membersihkan wajah dari kotoran dan memiliki kandungan yang mampu menjaga kelembaban dan menenangkan kulit wajah. Bahan baku utama pembuatan sabun adalah minyak dan lemak, salah satu bahan campuran pembuatan sabun facial wash adalah minyak kelapa murni (virgin coconut oil) diyakini memiliki banyak manfaat pada komposisinya yang terdiri dari asam lemak jenuh rantai sedang dan bersifat anti mikroba. Kulit buah pisang mengandung senyawa flavonoid sebagai anti hyperpigmentasi. Hyperpigmentasi merupakan salah satu kondisi munculnya bercak gelap pada kulit yang diakibatkan paparan sinar matahari, penuaan, hemokromatosis dan penggunaan obat-obatan tertentu. Tujuan penelitian ini adalah untuk mengetahui hasil pembuatan sabun facial wash berbasis minyak kelapa murni (virgin coconut oil) dengan penambahan ekstrak kulit pisang ambon dengan uji organoleptic dan skala hedonic. Penelitian ini dilakukan terhadap sepuluh panelis dengan penilaian banyak busa, warna, aroma, tekstur, dan reaksi alergi. Panelis diminta memberikan penilaian dengan produk sabun facial wash yang ada dipasaran (produk pembanding). Berdasarkan hasil uji organoleptic didapatkan hasil penilaian produk facial wash berbasis minyak kelapa murni dengan ekstrak kulit pisang ambon (Musa Paradisiaca L.) sebagai anti hiperpigmentasi mendapatkan point lebih unggul pada uji organoleptic warna dan aroma. Sedangkan, pada produk pembanding mendapatkan point lebih unggul pada uji organoleptic banyak busa dan tekstur. Namun, tidak terjadi reaksi alergi pada sepuluh panelis terhadap kedua produk.
Pengaruh Gaya Kepemimpinan Dan Disiplin Kerja Terhadap Kinerja Pegawai Dengan Kepuasan Kerja Sebagai Variabel Moderating Pada Dinas Perumahan Dan Kawasan Permukiman Kota Metro
Authors: Suwarto  , Suryadi  , Sari Intan Novita 
Published: June 2024

Based on the previous observation which yielded the initial data regarding to the level of achievement on the employee performance, it turned out that it still did not fully show good achievement. An institution needs a leader who is able to provide direction to his subordinates where one of the goals is to direct all employees for obeying the rules have been made in order to make the employee performance increase. For this reason, it is necessary to have a quality leader so that later on he is able to lead his subordinates well so that, the organizational goals can be achieved effectively and efficiently. This study aimed at determining whether the leadership style of a leader influenced the employee performance, to determine whether work discipline effects employee performance, to determine whether the leadership style and work discipline affect the job satisfaction as a moderating variable and to determine whether work discipline influences job satisfaction as a moderating variable. The sample of this research was the employees of the Housing Department and Residential Areas of Metro City with totaling 59 employees. The collected data were carried out by distributing questionnaires. Furthermore, the collected data were analyzed by applying the Validity Test, Reliability Test, Data of Frequency Distribution, Normality Test, Linearity Test, Homogenia Test, Multiple Linear Regression Analysis, T Test, Coefficient of Determination Test, MRA Interaction Test and Statistical Hypothesis test using program (SPSS 25). The results of this study showed that there was a positive and significant influences between Leadership style on Employee Performance, there was a Positive and Significant influence between Work Discipline and Employee Performance, there was a positive and significant influence of Leadership Style between Employee Performance and Job Satisfaction as a Moderating Variable, there was a positive and significant influence Significance of Work Discipline and Employee Performance on Job Satisfaction as a Moderating Variable.
Keywords: Leadership Style, Work Discipline, Employee Performance, Job Satisfaction.
Analisis Penggunaan Modal Kerja Terhadap Profitabilitas Perusahaan Pada PT.Indofood Sukses Makmur Tbk Tahun 2019 – 2021
Authors: Sri Retnaning Rahayu  , Ardiansyah Japlani  , Febria Ayu Puspita Ningrum  
Published: June 2024

The purpose of this study was to determine whether there is an influence of cash turnover, inventory turnover, and inventory turnover on profit margins at PT. Indofood Sukses Makmur, Tbk in 2019-2021. This type of research is descriptive research using a quantitative approach and using secondary data, namely data obtained from materials available in books, and other sources that are relevant to this research and will assist in processing the company's financial data obtained. The data analysis technique used in this study is panel data which is a combination of time series data and cross section data. Therefore, panel data has a combination of characteristics, namely data consisting of several objects and covering several periods of time. The results of the study show that cash turnover does not significantly affect profit margin at PT Indofood Sukses Makmur Tbk in 2019-2021. Receivable turnover has a negative and significant effect on profit margins. Inventory turnover has a positive and significant impact on profit margins at PT Indofood Sukses Makmur Tbk. Cash turnover, accounts receivable turnover, and inventory turnover have no simultaneous effect on profit margins.
Conservadorismo e violência simbólica žižekiana em “Porra, Santo Antônio”, de Maya Falks
Authors: Almeida Marcia Geralda de 
Published: June 2024

Este artigo teve como objetivo interpretar o conto “Porra, Santo Antônio”, da escritora Maya Falks, a partir do conceito de violência (objetiva) simbólica do filósofo esloveno Slavoj Žižek, demonstrando como a violência simbólica funciona como mecanismo de manutenção da ordem simbólica e, pode, eventualmente, irromper em formas de violência subjetiva. Trata-se de um estudo qualitativo e de base interpretativa, baseado nos pressupostos do materialismo lacaniano. O materialismo lacaniano é uma teoria que vincula os pressupostos da psicanálise de Jacques Lacan ao materialismo dialético de Karl Marx, propondo reflexões sobre o funcionamento das relações humanas, considerando não só a luta de classes, mas também as implicações do inconsciente, da linguagem etc. Seus principais disseminadores são os filósofos Slavoj Žižek e Alain Badiou. Por meio deste estudo teórico, verificamos a existência de uma violência objetiva simbólica perceptível pela observação atenta dos usos lexicais no enredo; essa violência simbólica estrutura as coordenadas do universo simbólico das personagens e faz emergir formas de violência subjetiva quando suas contradições vêm à tona.
Palavras-chave: violência simbólica; Slavoj Žižek; Maya Falks.
Treatment of Industrial Effluents in a Heavy Metal Sector Company: From Environmental Compliance to a Branding Strategy
Authors: Fontenelle Anderson Rocha , Araujo Gilberto Jorge da Cruz , Musci Marcelo , Souza Edmilson Monteiro de , Cardoso Alexander Machado , Silva Neto Dario Nepomuceno da 
Published: June 2024

Purpose: This work aims to conduct a review of the entire process of an effluent treatment plant installed in the manufacturing plant of a heavy metals sector company that treats the water used in the process of washing parts and equipment from customers sent for maintenance located in Rio de Janeiro city.

Design/methodology/approach: Exploratory qualitative descriptive research was employed. Data for the development of the work were collected through a checklist created with some guiding questions required by the environmental agency of the State of Rio de Janeiro, Brazil. This checklist identified compliance points and areas for improvement in its management. In addition, other sources of research such as books, websites, newspapers, and magazines that address important topics related to the treatment of industrial effluents, branding, environmental compliance, and other environmental subjects were used.

Findings: Through a review, a branding strategy was developed to promote eco-efficient practices, ensuring that all stakeholders are aware of the company's environmental commitment and how this process can yield significant results for the company's image in an increasingly competitive market.

Discussion: Business management has undergone a significant paradigm shift, as companies can no longer focus their strategies solely on profits. Instead, they must base them on social and environmental principles to avoid facing sanctions that could result in reduced profits, tarnished reputation, or even closure.
Interdisciplinary Records in Agrarian Settlements of The Upper Sergipe Hinterland: Community-Based Tourism As An Economic Alternative
Authors: Martinez Daniela Rollemberg Lopez , Soares Maria José Nascimento , Brandão Camilo Rafael Pereira , Bezerra Talitha Silva Cavalcante 
Published: June 2024

Objective: To analyze the historical and socio-environmental context in which the riverside dwellers and communities of the Upper sergiano hinterlands are inserted, the possibilities and tourist potential of the region.

Method: a bibliographic review was carried out from the survey of historical documents in the databases of Scientific Electronic Library Online - Scielo, Google School, and capes repository from the following searchers: Riverside Community; Agrarian Settlements; Alto Sertão Sergipano; Tourist Territorialities; Community-Based Tourism and Sustainable Development.

Notes and conclusion: Starting from the historical review carried out by the authors, Alto Sertão has exuberant natural scenarios, highlighting also in cultural diversity, crafts and regional gastronomy. Although the locus of the research is made up of traditional riverside communities and agrarian settlements, it is denoted the hegemony of conventional tourism over community-based tourism in the region, due to the absence of consistent public policies, combined with the socioeconomic complexity of the semi-arid region.

Implications of the research: It highlights the tourist territorialities of the agrarian settlements of Alto Sertão as an economic alternative for the traditional riverside communities, emphasizing the importance of the organization for coping with the negative impacts of conventional tourism and its role in the management of the local tourist activity.

Originality: Contributes to the discussion of strengthening the tourist activity in a sustainable and inclusive way in the settlements of Alto Sertão Sergipano.
How Does The Official Indonesian Tourism Website Apply The Dimensions of The Experiential Marketing?
Authors: Mwinuka Nickson Nazarenus , Phabiano Edward , Sumarwan Antonius 
Published: June 2024

This paper aimed to explore out how the dimensions of experiential marketing have been applied in the official Indonesian tourism website. It is the qualitative paper which basically focuses on content analysis, data were obtained through literature documents (journals and articles) and internet documents. The dimensions discussed on engaging all five senses, creating link with customers, creating surprise, themes the experience (giving a clear message) and memorability. Basing on the way the website operates, the findings show that, the dimensions towards implementing the experiential marketing while promoting and advertising the attractions in Indonesia is fulfilled. The paper shows how the internet revolutionary has changed the way of marketing the tourism products when experiential marketing is well utilized. The purpose of this paper was to find out whether the experiential marketing via website is done right or not and the result showed ,the dimensions are followed and applied but not smarter as it was expected, there is need to have more research which will account how many consumers visit the destinations due to the role played by the website, to this point the paper can help the academicians to conduce more researches on this point, the government and other policy makers will be helped by the paper to amend and do some improvements on the way of running the website. For example, some of the destinations are not well described, meaning no clear details concerning the destinations especially to the new customers who visit the website for the first time.
Discriminación y limitaciones en el uso de la lengua española: el fetiche de la norma en Twitter (X)
Authors:   Universidade de Vigo (España), Méndez Santos María del Carmen , Rodríguez Barcia Susana ,   Universidade de Vigo (España)
Published: June 2024

This paper discusses the restrictions that the standard norm of Spanish imposes on speakers. T he analysis has been based on opinions expressed on the social network Twitter regarding memes that present spelling or grammatical deviations from the standard norm of Spanish. Firstly, some terms are discussed to contextualize this phenomenon, such as linguistic profiling and linguistic discrimination (linguicism, accentism, and glottophobia). After that, a corpus of one hundred comments collected from Twitter between November and December 2022 is analyzed. This corpus serves as textuality to illustrate how society reproduces discriminatory patterns based on the assumption of regulations understood in terms of command and prestige. The main conclusion of this research is that the restrictive nature of the languages governed by normative institutions limits the innovative practices of a linguistic community and encourages discriminatory and classist practices.
Cerebral vasospasm occurring immediately after endoscopic transsphenoidal resection of a pituitary adenoma: A case report
Authors: Aihara Satoshi , Umegaki Takeshi , Soeda Takehiro , Iwamura Haruka , Takeda Junichi , Nonaka Masahiro , Kamibayashi Takahiko 
Published: June 2024

Background:
Cerebral vasospasm is a rare postoperative complication of transsphenoidal pituitary adenoma surgery with potentially severe consequences. These vasospasms generally have a delayed presentation at a mean of 8 postoperative days. We report an unusual case of hyperacute onset of cerebral vasospasm that occurred immediately after surgery.

Case Description:
A 38-year-old man underwent endoscopic transsphenoidal surgery for a nonfunctioning pituitary adenoma. The patient experienced mild subarachnoid hematoma during surgery. Three hours after surgery, he developed rightward conjugate eye deviation and complete paralysis of the left upper and lower extremities. Diagnostic imaging revealed cerebral vasospasm in both middle cerebral arteries, and symptoms improved after intra-arterial administration of fasudil hydrochloride.

Conclusion:
There is a need for prompt diagnosis and therapeutic intervention when typical symptoms of cerebral vasospasm, such as paralysis, occur at any time during the postoperative course.
DIALÉTICA DOS TÓPICOS DE ARISTÓTELES
Authors: Szynwelski Cristiane 
Published: June 2024

Este artigo contém um esboço da dialética dos Tópicos de Aristóteles e explicações sobre algumas passagens da obra, como uma propedêutica à sua leitura. A primeira seção contém uma síntese sobre o problema da definição da dialética aristotélica e explica que sua solução demanda uma pesquisa além dos Tópicos. A segunda e terceira seções mostram o que é possível se conhecer sobre a dialética com o estudo dessa obra: uma técnica de raciocínio conforme é aplicada ao treinamento acadêmico e também, em certa medida, às disputas dialéticas da antiga Grécia. O artigo também chama a atenção para vários detalhes e diferenças a respeito da contextualização de passagens dos Tópicos, o que serve para prevenir erros de interpretação.
Peningkatan Kemampuan Guru SD Menggunakan Google Classroom sebagai Media Pembelajaran di Masa Pandemi
Authors: Aziza Nurul , Purnamasari Wulan , Aisyah Siti , Lindawati Desy 
Published: June 2024

Keputusan bersama menteri Pendidikan Dan Kebudayaan, Menteri Agama, Menteri Kesehatan, Dan Menteri Dalam Negeri Republik Indonesia Nomor 01/Kb/2020, nomor 516 Tahun 2020, Nomor Hk.03.01/Menkes/363/2020, dan nomor 440-882 tahun 2020 tentang Panduan Penyelenggaraan Pembelajaran Pada Tahun Ajaran 2020/2021 dan Tahun Akademik 2020/2021 di Masa Pandemi Corona Virus Disease 2019 (Covid-19) maka dilarang melakukan proses pembelajaran tatap muka di satuan pendidikan. Agar pembelajaran dapat dilakukan , maka salah satu jalan adalah melalui pembelajaran daring. Media daring yang sebelumnya belum pernah dilakukan oleh para guru, khususnya para guru sekolah dasar tentu saja merupakan kendala tersendiri. Oleh karena itu untuk sosialisasi dan pelatihan bagi guru dalam penggunaan media pembelajaran sekolah. Untuk itulah dilakukan program pelatihan media pembelajaran daring kepada guru sekolah dasar dengan aplikasi google classroom. Khususnya diberikan kepada guru sekolah dasar di wilayah sekitar Universitas Maarif Hasyim Latif (UMAHA). Program ini bertujuan untuk memberikan pengetahuan tentang penggunaan google classroom sebagai media pembelajaran online yang dilaksanakan oleh para dosen dan mahasiswa Universitas Maarif Hasyim Latif (UMAHA). Metode program ini dalam bentuk pelatihan secara offline dengan peserta guru sekolah dalam jumlah terbatas dengan tetap memperhatikan protokol kesehatan. Hasil dari kegiatan ini adalah peningkatan kemampuan guru sebesar 75% dapat membuat materi, tugas dan komunikasi interaktif pembelajaran dengan classroom.
Creative Destruction: Pengembangan Desa Wisata Pujon Kidul di Kabupaten Malang
Authors: Pambudi Setyoadi , Novilia Evita , Anindita Erwinda 
Published: June 2024

Desa wisata Pujon Kidul merupakan desa percontohan di Kabupaten Malang, yang di kembangkan sejak tahun 2014. Desa wisata ini salah satu upaya yang di lakukan oleh pemerintah untuk meningkatkan perekonomian melalui sektor pariwisata, sesuai dengan nawacita Presiden RI, yaitu pembangunan dimulai dari desa. Adanya desa wisata di Pujon dapat membantu mengentaskan kemiskinan, mengurangi jumlah pengangguran, meningkatkan pendapatan masyarakat dan desa, serta pembangunan infrastruktur. Ada beberapa produk wisata di daerah Pujon Kidul Kabupaten Malang diantaranya, cafe sawah, air terjun sumber pitu, agro wisata petik sayur dan buah, tracking gunung kawi, wisata outbound, kesenian sadukan, dan sentral olahan susu sapi, serta wisata edukasi sapi ternak. Di Desa Pujon juga ditunjang oleh Bank Pelat Merah yang mampu memberikan Kredit Usaha Rakyat (KUR), sehingga masyarakat lebih mudah dalam modal dan pengembangan usaha. Kepala Desa Pujon Kidul, pemerintah daerah dan pusat sangat mendukungkebijakan pariwisata yang di tawarkan oleh desa pujon kidul. Sehingga regulasi dan perijinan semakin mudah, disertai dengan pendanaan dari pusat dan daerah, melalui dana alokasi dana desa, dana desa, bantuan pemerintah daerah, yang berakibat semakin cepat berkembangnya Desa Pujon Kidul, di buktikan dengan pendapatan asli desa terbesar di Kabupaten Malang dengan kisaran 85 juta per tahun.