bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumers and carers as partners in mental health research: Reflections on the experience of two project teams in Victoria, Australia
Authors: Callander Rosemary , Ning Lei , Crowley Anna , Childs Bianca , Brisbane Pam , Salter Tony 
Published: April 2011

ABSTRACTA successful working partnership in research between a consumer project team from the Victorian Mental Illness Awareness Council and a carer project team from the Victorian Mental Health Carers Network was forged during their collaborative involvement in an innovative 2‐year pilot project funded by the Victorian Government of Australia. This project trialled new ways of capturing consumer and carer experiences of mental health services, and that feedback was integrated into service quality improvement. Towards the end of the project, an external facilitator was used to enable the two teams to reflect on their experience of working together so that their joint story could be shared with others and used to promote further use of this approach in the mental health field. Main findings included the importance of having strong support and belief at leadership levels, opportunities to build the relationship and develop mutual trust and respect, a common vision and a clearly articulated set of values, targeted training appropriate to the needs of the team members, independent work bases, and mutual support to overcome challenges encountered during the project. The experience forged a close working relationship between the two teams and has set the scene for further participation of consumers and carers in research and innovative quality‐improvement processes in the mental health field.
Fetal and neonatal anemia associated with anti‐Jra: A case report showing a poorly hemolytic mechanism
Authors: Sasamoto Naoko , Tomimatsu Takuji , Nagamine Keisuke , Oshida Machiko , Kashiwagi Hirokazu , Koyama Shinsuke , Kanagawa Takeshi , Arahori Hitomi , Tomiyama Yoshiaki , Kimura Tadashi 
Published: April 2011

AbstractAlthough recently published case reports suggest the significance of Jra alloimmunization in the obstetric setting, the involved mechanism still remains unclear. Here we report a case of severe fetal and neonatal anemia associated with anti‐Jra alloimmunization, which was successfully managed using Doppler assessment of peak systolic velocity of the fetal middle cerebral artery (MCA‐PSV). A Japanese woman with anti‐Jra (titer 1024) was referred to our department at 20 weeks' gestation. As fetal MCA‐PSV exceeded 1.5 multiple of median, labor was induced and a female neonate of 1998 g was delivered vaginally at 33 weeks and 5 days of gestation. The infant's hematocrit and hemoglobin levels were 25.4% and 82 g/L, respectively, but her total bilirubin level (15 µmol/L; 0.9 mg/dL) and reticulocyte counts (4.5%) were low. During the course, the infant showed no apparent signs of hemolysis. Jra alloimmunization should be recognized as a possible cause of fetal anemia with no direct hemolytic process.
Androgens and sexual dysfunction in naturally and surgically menopausal women
Authors: Alarslan Demet , Sarandol Aslı , Cengiz Candan , Develioglu Osman H. 
Published: April 2011

AbstractAim:  To evaluate the influence of surgical versus natural menopause on sexual dysfunction, and the role of androgens in that context.Material & Methods:  Sexual functioning and androgen levels were studied in 35 surgically and 83 naturally menopausal women. Sexual dysfunction was defined as a total score of less than 23 on the Female Sexual Function Index.Results:  Sexual dysfunction was significantly more common in surgically than in naturally menopausal women (65.7% vs 44.6%; P = 0.036). The mean total testosterone level in women with sexual dysfunction was significantly lower than that in their counterparts (49.3 ± 21.0 vs 58.8 ± 23.6 ng/mL; P = 0.022). On the other hand, androgen levels did not differ significantly between surgically and naturally menopausal women. Androstenedione (B = 2.253; P = 0.039) and dehydroepiandrosterone sulfate levels (B = 0.222; P < 0.001), and time from menopause (B = −0.064; P = 0.040) were found to be independent determinants of total testosterone levels. While the duration of menopause was significantly longer in surgically menopausal women, this co‐factor was not an independent predictor of sexual dysfunction. Logistic regression analysis proved mode of menopause and total testosterone levels to be the only two independent determinants of sexual dysfunction.Conclusions:  Our findings suggest that while surgical menopause is detrimental to sexual functioning by itself, lower testosterone levels are predictive of sexual dysfunction, especially in naturally menopausal women.
An intrauterine device as a possible cause of change in the microbial flora of the female genital system
Authors: Kaliterna Vanja , Kučišec‐Tepeš Nastja , Pejković Lidija , Zavorović Srđan , Petrović Sanja , Barišić Zvonimir 
Published: April 2011

AbstractAim:  An intrauterine device (IUD), used by millions of women worldwide, is one of the most efficient methods of contraception. The goal of our study was to compare a group of women using the IUD to a control group.Material & Methods:  The survey included 236 women of fertile age from gynaecological practices in the area of Split and Dalmatia County, Croatia. The subjects were divided into two groups: IUD users and a control group (women not using any contraception methods). Sampling, transportation, sample processing in the laboratory and interpretation of results were conducted using standard microbiological procedures and methods.Results:  Opportunistic bacteria were statistically more frequently isolated among IUD users (P < 0.001). The most frequently isolated bacteria in both groups were Escherichia coli and Ureaplasma urealyticum with significantly higher rates in IUD users (P < 0.001). Both colonization and infection had higher rates in IUD users (P < 0.001). There were no significant differences either in the frequency of bacteria isolation regarding different IUD types (P = 0.93), or in relation to duration of IUD use (P = 0.67).Conclusions:  Based on the data in our study IUD users have an increased chance of developing a cervical infection caused by the bacteria Escherichia coli and Ureaplasma urealyticum. Therefore, before IUD insertion women should be screened and treated for asymptomatic vaginal or cervical infections to prevent possible serious IUD‐associated infections.
A pregnant woman with clinical and radiological findings compatible with posterior reversible encephalopathy syndrome in early pregnancy without discernable underlying disorders: Atypical type of this syndrome?
Authors: Matsubara Shigeki , Fujita Akifumi , Muramatsu Shin‐ichi , Usui Rie , Chikazawa Kenro , Suzuki Mitsuaki 
Published: April 2011

AbstractPosterior reversible encephalopathy syndrome, if it occurs in late pregnancy, requires pregnancy termination. Here, we report a woman without a discernable underlying condition who developed neurological deficits at 14 weeks of pregnancy. Magnetic resonance imaging demonstrated an occipitoparietal brain lesion suggestive of posterior reversible encephalopathy syndrome. Neurological symptoms ameliorated spontaneously and she continued her pregnancy to term. A decision to terminate pregnancy based on only neurological and magnetic resonance imaging findings should be avoided.
Impact of palliative urinary diversion by percutaneous nephrostomy drainage and ureteral stenting among patients with advanced cervical cancer and obstructive uropathy: A prospective cohort
Authors: Lapitan Marie Carmela M. , Buckley Brian S. 
Published: April 2011

AbstractAim:  Obstructive uropathy is a recognized complication in advanced cervical cancer. Urinary diversion is commonly used to bypass the obstruction and improve renal function. The degree of survival benefit that diversion offers is not well established and its impact on quality of life (QoL) is uncertain. This study considered these factors in order to inform treatment decisions.Methods:  This study examined a prospective cohort of patients with advanced cervical cancer and obstructive uropathy in Manila, Philippines. Age, cancer treatment status, comorbidities, serum creatinine level, degree of obstructive uropathy and QoL were recorded at baseline. Patients with creatinine values >150 µmol/L, or who were being considered for radiotherapy or nephrotoxic chemotherapy or manifesting uncontrolled or recurrent uropathy‐related urinary tract infection, were offered diversion. Follow‐up data collection was at 3, 6, 9 and 12 months from cohort entry.Results:  Of the 230 patients invited, 205 patients joined the cohort. Complete data were available for 198, of whom 93 underwent diversion, 56 required diversion but elected not to receive it, and 49 did not require it. Although survival at 12 months among those who underwent diversion was no greater than among those who required but elected not to receive the procedure, diversion was associated with significantly improved chance of survival in the shorter term. There was no significant difference in the QoL between the groups throughout the study.Conclusion:  With no evidence of an impact on QoL, the decision to offer diversionary surgery might be based solely on a survival benefit, which is modest but potentially important to patients.
Cardiomyopathy and heart failure in children: anesthetic implications
Authors: Rosenthal David N. , Hammer Gregory B. 
Published: April 2011

SummaryThe purpose of this article is to provide a brief but systematic overview of heart failure and cardiomyopathy in children and the anesthetic management of these patients. We will begin with disease definitions and descriptions of the disorders. Our review will include the epidemiology and etiology of the more prevalent underlying causes of heart failure, the principal pathophysiology of the specific cardiomyopathies, as well as the common therapies in use today in both inpatient and outpatient settings. Important implications for anesthetic management will be highlighted.
Uncovered Interest Parity: Cross‐Sectional Evidence
Authors: Lee Byung‐Joo 
Published: April 2011

AbstractUncovered interest parity (UIP) is estimated for short‐term horizons from one month to 12 months using a large number of cross‐sectional bilateral exchange rates. In contrast to conventional time‐series UIP, cross‐sectional UIP is examined with a single‐equation estimation and panel regression model estimation. The exchange rates analyzed here include a broad spectrum of countries: developed, developing, low‐inflation, and high‐inflation countries. Based on the empirical evidence, there does not appear to be a well‐publicized UIP puzzle for cross‐sectional UIP, and the slope estimates remain largely between zero and one throughout the sample periods, with a few exceptions. Evidence of UIP is more clear for low inflation countries than for high inflation countries. As interest rate maturity becomes longer from one month to 12 months, the UIP relationship becomes weaker.
Creating Backward Linkages from Multinationals: Is there a Role for Financial Incentives?
Authors: Görg Holger , Hanley Aoife , Strobl Eric 
Published: April 2011

AbstractWe investigate whether government subsidies encourage foreign multinationals to create linkages with domestic suppliers. To this end we use a unique panel dataset of foreign multinationals located in Ireland for which we have exhaustive information on grant receipt. Our results indicate that while European and US foreign plants develop backward linkages independently of grant receipt, multinationals from other parts of the world respond positively to government support. Our results hold even when controlling for the possible endogeneity of grants and the boundedness of the linkage variable. We conclude that governments should not apply a “one‐size‐fits‐all” approach to incentivizing foreign multinationals.
Commercial Policy and Foreign Ownership
Authors: Ishikawa Jota , Sugita Yoichi , Zhao Laixun 
Published: April 2011

AbstractForeign multinationals often not only export but also control local firms through FDI. This paper examines the various effects of trade and industrial policies when exports and FDI coexist. We focus on the case in which a foreign firm has full control of a local firm through partial ownership. Cross‐border ownership on the basis of both financial interests and corporate control leads to horizontal market linkages through which tariffs and production subsidies may harm locally owned firms but benefit the foreign firm. Foreign ownership regulation benefits locally owned firms. These results could have strong policy implications for developing countries that attract an increasing share of world FDI.
Export Variety, Revenue, and Productivity in China
Authors: Chen Bo 
Published: April 2011

AbstractIn this paper I argue through empirical testing that it is the underlying export variety that helps to explain the strong correlation between China's provincial export revenue and productivity. The empirical model maps export varieties into provincial GDP functions with multiple sectors by price index theory. By employing panel data that covers all 31 executive districts of mainland China from 1998 to 2005, I find that export varieties, via export revenue, significantly affect productivity: it accounts for 44.1% of interprovincial TFP differences and 36.6% of within‐province TFP growth; a 10% increase in export variety leads to a 1.4% productivity growth in China.
Is China's Antidumping More Retaliatory than that of the US?
Authors: Bao Xiaohua , Qiu Larry D. 
Published: April 2011

AbstractAntidumping (AD) investigations are widespread. China and the US are two big users and targets of AD investigations. They, respectively, represent developing and developed countries on one hand, and new AD users and traditional AD users on the other. In this paper, using AD filing data of these two countries from 1991 to 2005, we explore whether China's AD is more retaliatory than that of the US. Our results obtained from negative binomial models with maximum likelihood techniques show that although both countries have some degree of retaliatory incentives in their AD filings, China is not more (or may even be less) retaliatory than the US. We also compare the two countries' similarities and differences in their AD responses to other factors such as macroeconomic conditions, contagions, and geographical distance.
Time Preference and Trade Imbalance
Authors: Kikuchi Toru , Hamada Koichi 
Published: April 2011

AbstractThis paper presents a unified theory of trade and investment in a world where the rate of time preference varies between countries. In the framework proposed by Buiter (1981), we can analyze a situation wherein two countries have different rates of discount. Here, the value of the debt to income does not converge to zero but remains constant even in the long run. Furthermore, we show that the existence of less‐capital‐intensive nontradables promotes capital movements: since a more patient country incompletely specializes in less‐capital‐intensive nontradables, capital must flow out of it.
JACOBIAN CLUSTER MUTATION ACROSS ADVERTISING AND INTERNET‐BASED MARKET COMMUNICATION
Authors: BUGGE MARKUS M. 
Published: April 2011

ABSTRACTThe advertising industry is currently undergoing a profound restructuring process, where traditional media like TV and print are being complemented and replaced by new forms of online and interactive advertising. The versatile and interactive nature of the Internet medium represents new opportunities and challenges for the advertising agencies that transcend their traditional role as developers of creative contents and campaigns. The paper discusses how this transformation process affects services in the new online market communication regime. Based on a case study on how the Internet affects the advertising industry and its related actors the paper argues that the introduction and growth of Internet‐based market communication leads to a convergence of creative, strategic and technical services. It is suggested that this represents a new production and market communication space in which the end consumer often plays a more pro‐active and participatory role. The paper argues that the convergence of skills and services across advertising and information and communications technology can be viewed as a Jacobian cluster mutation across related and co‐evolving industrial agglomerations. The empirical findings are interpreted and conceptualised as a cyclical relationship between knowledge externalities associated with specialisation and differentiation.
Delayed myocardial preconditioning induced by cobalt chloride in the rat: HIF‐1α and iNOS involvement
Authors: Belaidi Elise , Beguin Pauline C. , Levy Patrick , Ribuot Christophe , Godin‐Ribuot Diane 
Published: April 2011

AbstractWe previously reported that acute exposure to intermittent hypoxia results in delayed cardioprotection against ischemia/reperfusion (I/R) injury and that the hypoxia‐inducible factor (HIF)‐1α, a transcriptional factor stabilized by hypoxia, as well as inducible nitric oxide synthase (iNOS) play a key role in this form of preconditioning. As cobalt chloride (CoCl2) is known to promote HIF‐1α stabilization by inhibiting prolyl hydroxylase activity, we hypothesized that CoCl2 could mimic the cardioprotective effects of hypoxia. Two groups of rats were administered 30 mg/kg twice of CoCl2 or sterile water. Twenty‐four hours later, hearts were perfused in Langendorff mode and subjected to an I/R protocol. Infarct size and functional recovery were studied. The role of iNOS was assessed by measuring myocardial iNOS content and by observing the effects of the iNOS inhibitor aminoguanidine (Ag, 100 μm, prior to ischemia). The role of HIF‐1α was investigated by preventing its stabilization using cadmium chloride (CdCl2, 1 mg/kg), administered 1 h before cobalt treatment. Treatment by CoCl2 significantly reduced myocardial infarction by 33% and increased coronary flow (CF) at reperfusion by 27% compared with control rats, and this was accompanied by a threefold increase in myocardial iNOS content. CdCl2 pretreatment and Ag perfusion abolished the beneficial effects on both infarct size and CF. Thus, the hypoxia‐sensitive transcription factor HIF‐1α and iNOS appear to play a pivotal role in the delayed pharmacological myocardial preconditioning induced by cobalt, thus mimicking the effects of hypoxic preconditioning. These results underscore the importance of prolyl hydroxylases as potential therapeutic targets for cardioprotection.
Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR‐γ‐related pharmacology
Authors: Song Min K , Roufogalis Basil D , Huang Tom H W 
Published: April 2011

Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes and remains a major cause of preventable blindness among adults at working age. DR involves an abnormal pathology of major retinal cells, including retinal pigment epithelium, microaneurysms, inter‐retinal oedema, haemorrhage, exudates (hard exudates) and intraocular neovascularization. The biochemical mechanisms associated with hyperglycaemic‐induced DR are through multifactorial processes. Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) plays an important role in the pathogenesis of DR by inhibiting diabetes‐induced retinal leukostasis and leakage. Despite DR causing eventual blindness, only a few visual or ophthalmic symptoms are observed until visual loss develops. Therefore, early medical interventions and prevention are the current management strategies. Laser photocoagulation therapy is the most common treatment. However, this therapy may cause retinal damage and scarring. Herbal and traditional natural medicines may provide an alternative to prevent or delay the progression of DR. This review provides an analysis of the therapeutic potential of herbal and traditional natural medicines or their active components for the slowdown of progression of DR and their possible mechanism through the PPAR‐γ pathway.LINKED ARTICLE This article is commented on by Costa and Ciccodicola, pp. 1–3 of this issue. To view this commentary visit http://dx.doi.org/10.1111/j.1476‐5381.2011.01443.x
Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress
Authors: Tian XY , Wong WT , Xu A , Chen ZY , Lu Y , Liu LM , Lee VW , Lau CW , Yao X , Huang Y 
Published: April 2011

BACKGROUND AND PURPOSE HMG‐CoA reductase inhibitors, statins, with lipid‐reducing properties combat against atherosclerosis and diabetes. The favourable modulation of endothelial function may play a significant role in this effect. The present study aimed to investigate the cellular mechanisms responsible for the therapeutic benefits of rosuvastatin in ameliorating diabetes‐associated endothelial dysfunction.EXPERIMENTAL APPROACH Twelve‐week‐old db/db diabetic mice were treated with rosuvastatin at 20 mg·kg−1·day−1 p.o.for 6 weeks. Isometric force was measured in isolated aortae and renal arteries. Protein expressions including angiotensin II type 1 receptor (AT1R), NOX4, p22phox, p67phox, Rac‐1, nitrotyrosine, phospho‐ERK1/2 and phospho‐p38 were determined by Western blotting, while reactive oxygen species (ROS) accumulation in the vascular wall was evaluated by dihydroethidium fluorescence and lucigenin assay.KEY RESULTS Rosuvastatin treatment of db/db mice reversed the impaired ACh‐induced endothelium‐dependent dilatations in both renal arteries and aortae and prevented the exaggerated contractions to angiotensin II and phenylephrine in db/db mouse renal arteries and aortae. Rosuvastatin reduced the elevated expressions of AT1R, p22phox and p67phox, NOX4, Rac1, nitrotyrosine and phosphorylation of ERK1/2 and p38 MAPK and inhibited ROS production in aortae from db/db mice.CONCLUSIONS AND IMPLICATIONS The vasoprotective effects of rosuvastatin are attributed to an increase in NO bioavailability, which is probably achieved by its inhibition of ROS production from the AT1R‐NAD(P)H oxidase cascade.