bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coexistence of intracranial aneurysm in 800 patients with surgically confirmed pituitary adenoma
Authors: Oh Min Chul , Kim Eui Hyun , Kim Sun Ho 
Published: February 2012

Object
The purpose of this study was to assess factors associated with intracranial aneurysm (IA) in patients with pituitary adenoma (PA). In addition, these patients were compared with a control group from the general patient population in terms of the age-matched prevalence rate and the pattern of distribution of IA.

Methods
The authors retrospectively reviewed 800 patients who received transsphenoidal surgery for PA and 3850 control patients from the general patient population who were evaluated for routine health care at the authors' institution between 2004 and 2010. All patients underwent MR imaging and MR angiography. Hormone assessment and pathological examination performed using immunohistochemical (IHC) staining were completed for patients with PA.

Results
Coexistence of IA in patients with PA was detected in 18 patients (2.3%). Multivariate analysis showed that age (p = 0.04) and cavernous sinus invasion (p < 0.001) were correlated with the increased incidence of IA, but hormone type, IHC staining, and sex were not associated. An age-matched comparison of the prevalence of IA showed an increased prevalence in patients with PA compared with the controls (p = 0.014), and when categorized according to age by decade, the 6th decade was significantly different (p = 0.039). However, the intracranial distribution pattern of IA did not demonstrate a significant difference.

Conclusions
Older age and the existence of a cavernous sinus invasion were correlated with increased incidence of IA in patients with PA. An age-matched comparison showed an increased incidence of IA in patients with PA than in the controls.
Treatment and outcomes of acute intracranial vertebrobasilar artery occlusion: one institution's experience
Authors: Webb Sharon , Yashar Parham , Kan Peter , Siddiqui Adnan H. , Hopkins L. Nelson , Levy Elad I. 
Published: February 2012

Object
The treatment of acute intracranial vertebrobasilar artery occlusion (VBO) has been described but often with poor results. The authors of this study set out to evaluate their institution's outcomes following multimodal treatment of VBO.

Methods
They retrospectively reviewed their endovascular database for all patients treated for acute intracranial VBO between December 2004 and June 2010. Twenty-four patients were identified. Two patients were excluded from evaluation—one because of incomplete medical records and one because the etiology was basilar stenosis and not stroke. Occlusion location, hypercoagulable causes, time to endovascular treatment, time to revascularization, comorbidities, devices used, procedural anticoagulation, and outcomes were analyzed.

Results
Among the 22 eligible study patients, the mean National Institutes of Health Stroke Scale (NIHSS) score at presentation was 15.3. The mean time from presentation to initiation of the endovascular procedure was 4.77 hours. The mean time for recanalization from the start of angiography was 1.63 hours. In 16 patients (73%), revascularization was successful (Thrombolysis in Myocardial Infarction [TIMI] score of 2 or 3). Thirteen (59%) of the 22 patients were discharged to home or a rehabilitation facility. One patient was transferred to a chronic care facility. The overall survival rate was 64%. The average NIHSS score for the 14 surviving patients at discharge was 3.9. At the follow-up (average 14.5 months, range 1–58 months), 10 patients (71%) had achieved good outcomes (modified Rankin Scale [mRS] score ≤ 2) and 4 (29%) had poor outcomes (mRS Score 3–6).

Conclusions
Published case series have historically shown poor outcomes and high mortality rates in association with the treatment of acute VBO, prompting surgeons to be less aggressive in the treatment of this disease than they might be otherwise. Data in this series show that the revascularization of posterior circulation occlusions is feasible and that good outcomes and lower mortality rates with newer endovascular technologies are possible, and thus more prompt and aggressive treatment of this disease may be warranted.
Mesures de gestion favorisant les coléoptères du bois dans une réserve forestière
Authors: Barbalat Sylvie 
Published: February 2012

Measures favouring saproxylic beetles in a forest reserve
The goal of this study is to propose conservation measures aiming at favouring saproxylic beetle populations, considering the general management of a forest reserve. The study site is a periurban forest above the city of Neuchâtel in the Swiss Jura. The studied habitats are oak and beech forests alternating with dry meadow patches and black pine (Pinus nigra) plantations. The general management goal of this forest reserve is to conserve rare plant associations and to preserve characteristical fauna and flora. In order to achieve these goals, the following management actions were undertaken: preserve open habitats, reduce black pine occurrence, restore and enhance oak forest and preserve islands of old growth.
An inventory of four beetle families (Cerambycidae, Buprestidae, Lucanidae and Cetoniidae) was made by means of direct collection. Between 2004 and 2009, twenty-five collecting tours lasting for an average of 1 hour 45 minutes were performed from the beginning of May to the beginning of July. Fifty-two beetle species were caught and grouped in six categories based on their larval ecology. For each of them, enhancing actions were proposed, potential conflicts between saproxylic beetle conservation and general management actions were discussed. In order to find a balance between sometimes contradictory actions, the best solution to promote an optimal biodiversity is a patchwork of forest and open biotopes. As far as saproxylic beetles are concerned, tree diversity should be enhanced and old trees preserved. In the open areas, old bushes growing in the edges should not be removed.
Wie gross sollen Altholzinseln sein?
Authors: Müller Markus , Lachat Thibault , Bütler Rita 
Published: February 2012

How large should old-growth islands be?
About 5% of the Swiss forest surface should be protected as natural forest reserves or as old-growth islands until 2030. This goal, which has been formulated by the Federal Office for the Environment and by the cantons, aims to promote the natural development of the forest and to conserve saproxylic species. Beside large-sized natural forest reserves, smaller old-growth islands may also play an important role. A bootstrapping method has been developed to define the minimal size of old-growth islands based on a field inventory in high forests without logging since at least 30 years. Three different indicators for habitat structures have been used to establish the ecological potential of old-growth islands: the total number of habitat structures, the amount of deadwood and the number of woodpecker trees. The threshold has been defined as the average of each indicator minus the standard error for different forest types. The surface of an island is determined at the point where 75% of the modeled surfaces are above the threshold, which guarantees a certain ecological potential. This surface reaches 0.7 ha for floodplain forests, 0.9 ha for beech and fir-beech forests and 1.2 ha for silver spruce-fir forests. The computed values are minimal rather than optimal surfaces for old-growth islands. With an increase of the surface, sustainability, quantity and quality of the habitats will be improved. Therefore, the size of old-growth islands should be larger whenever the local circumstances are favorable.
Durch Standards die Interoperabilität von forstlichen Warenwirtschaftssystemen verbessern
Authors: Blattert Clemens , Lemm Renato , Ehrhardt Ina , Seeling Ute 
Published: February 2012

Improving the interoperability of forest enterprise resource planning systems with standards
To ensure forestry, the timber industry and their products are competitive, flexible and time-optimized logistics processes are necessary. These, in turn, require a fast, safe and efficient flow of information, for which IT-based enterprise resource planning systems (ERP) provide an essential basis. ERP systems are increasingly being used in the forestry-wood-products chain. ERP systems that can work together beyond their original application range are needed for an efficient information flow. Because of the heterogeneity of these systems, simple and clear standards must be defined at the interfaces. That means the computers have to use the same language not only technically but also from the point of view of the content to be communicated. The following article analyzes the strengths and weaknesses of the four standardization efforts Eldat, FHPDAT, Papinet and Cosemat and derives some initial recommendations for further developments.
Next‐generation sequencing‐based transcriptomic and proteomic analysis of the common reed, Phragmites australis (Poaceae), reveals genes involved in invasiveness and rhizome specificity
Authors: He Ruifeng , Kim Min‐Jeong , Nelson William , Balbuena Tiago S. , Kim Ryan , Kramer Robin , Crow John A. , May Greg D. , Thelen Jay J. , Soderlund Carol A. , Gang David R. 
Published: February 2012

• Premise of the study: The common reed (Phragmites australis), one of the most widely distributed of all angiosperms, uses its rhizomes (underground stems) to invade new territory, making it one of the most successful weedy species worldwide. Characterization of the rhizome transcriptome and proteome is needed to identify candidate genes and proteins involved in rhizome growth, development, metabolism, and invasiveness.• Methods: We employed next‐generation sequencing technologies including 454 and Illumina platforms to characterize the reed rhizome transcriptome and used quantitative proteomics techniques to identify the rhizome proteome.• Key results: Combining 336514 Roche 454 Titanium reads and 103350802 Illumina paired‐end reads in a de novo hybrid assembly yielded 124450 unique transcripts with an average length of 549 bp, of which 54317 were annotated. Rhizome‐specific and differentially expressed transcripts were identified between rhizome apical tips (apical meristematic region) and rhizome elongation zones. A total of 1280 nonredundant proteins were identified and quantified using GeLC‐MS/MS based label‐free proteomics, where 174 and 77 proteins were preferentially expressed in the rhizome elongation zone and apical tip tissues, respectively. Genes involved in allelopathy and in controlling development and potentially invasiveness were identified.• Conclusions: In addition to being a valuable sequence and protein data resource for studying plant rhizome species, our results provide useful insights into identifying specific genes and proteins with potential roles in rhizome differentiation, development, and function.
La fondation de la Banque des règlements internationaux
Authors: Clavert Frédéric 
Published: February 2012

Cet article s’attache à décrire et à analyser la création de la Banque des Règlements internationaux en 1930. Se fondant essentiellement sur des archives allemandes et françaises, il tente d’expliquer pourquoi les banquiers centraux membres du Comité Young puis du Comité d’organisation de la banque des règlements internationaux ont fini, malgré une attitude ambivalente de la Reichsbank et de Hjalmar Schacht, par se mettre d’accord sur les fonctions et la fondation de la BRI. Dans ce processus, l’accord des banquiers centraux sur l’idée d’indépendance des banques centrales est fondamental.
L'indépendance de la Banque nationale de Roumanie en question : le gouverneur Burillianu et la mission de la Banque de France au début des années trente
Authors: Racianu Ileana 
Published: February 2012

Cet article analyse les relations entre le gouverneur de la Banque nationale de Roumanie, Dimitrie Burillianu, et le pouvoir politique au début des années trente. Ayant refusé d’accepter la prolongation de la mission financière de la Banque de France, qui devient une sorte de conditionnalité, imposée au Gouvernement roumain en échange d’un emprunt international, le gouverneur Burillianu est révoqué par décret royal le 10 mars 1931. Cette mesure illustre la fragilité de l’indépendance que la Banque nationale de Roumanie avait acquise le 7 février 1929, date à laquelle la monnaie roumaine avait été stabilisée grâce à un emprunt international organisé par la Banque de France.
Le « Comité Werner » : nouvelles archives
Authors: Rodica Danescu Elena 
Published: February 2012

Centrées sur le « plan d’une union économique et monétaire par étapes » présenté publiquement le 8 octobre 1970, les recherches dans le fonds des archives inédites de la famille Werner permettent la mise en lumière tant du déroulement des travaux du comité Werner, de l’incidence du plan Werner sur la poursuite du chemin vers l’Union économique et monétaire, que de la contribution personnelle de son président à l’élaboration de ce rapport, ainsi qu’à l’obtention du compromis politique nécessaire pour faire avance l’Europe.
Les banquiers centraux de l'échec du plan Werner à la création du SME, 1974-1979
Authors: Mourlon-Druol Emmanuel 
Published: February 2012

Cet article analyse le rôle des banquiers centraux dans la coopération monétaire européenne, de l’échec du plan Werner à la création du Système monétaire européen (SME). Le rôle des banquiers centraux dans les négociations du SME est généralement considéré comme mineur : la principale caractéristique des négociations de 1978 fut en effet l’effort du président français Valéry Giscard d’Estaing et du chancelier allemand Helmut Schmidt pour éviter les banquiers centraux, prévoyant leur opposition au projet franco-allemand. Utilisant des archives allemandes, britanniques, françaises et communautaires, cet article insiste plutôt sur la continuité de la coopération entre banquiers centraux durant la seconde moitié des années 1970, la formation progressive d’un consensus autour de la position de la Bundesbank, et souligne combien les banquiers centraux sont insérés dans une élite monétaire transnationale plus large incluant conseillers économiques et ministres des Finances.
La Banque de France et la contrainte européenne en France (1979-1983)
Authors: Duchaussoy Vincent 
Published: February 2012

Cet article se propose d’examiner l’existence d’une contrainte politique imposée par les institutions communautaires européennes au gouvernement français, de la mise en place du Système monétaire européen au « tournant de la rigueur » adopté par le gouvernement Mauroy en mars 1983, et d’en identifier les acteurs. Ce sera l’occasion de saisir la répercussion sur le plan des relations communautaires, de la politique économique menée par la France après l’élection de François Mitterrand à la présidence de la République, à contre-courant vis-à-vis des autres pays de la Communauté. On s’interrogera, enfin, sur l’action de la Banque de France, en désaccord profond avec le gouvernement quant à la définition de la politique économique et monétaire du pays, dans les instances communautaires au sein desquelles elle est amenée à siéger.
Le rôle des comités d'experts du Comité des gouverneurs des banques centrales de la CEE
Authors: Raymond Robert 
Published: February 2012

Le témoignage de Robert Raymond éclaire pour la première fois l’histoire du groupe des experts monétaires constitué en 1973 auprès du Comité des Gouverneurs de la CEE. Il montre le rôle joué par la communauté informelle et transnationale des experts des banques centrales dans la genèse et la mise en œuvre de l’Union économique et monétaire, sans solution de continuité des années 1970 aux années 2000.
Le maternel déifié
Authors: Denis Paul 
Published: February 2012

Résumé Le sentiment religieux dérive d’un « maternel purifié ». Pour se maintenir ce sentiment religieux doit nier la dimension phallique et sexuelle de la mère, présente cependant à l’arrière-plan des expériences d’exaltation et des expériences mystiques, cultes secrets résultant d’une inversion béate du sentiment de désarroi. Au plan individuel, le passage du maternel au paternel doit être surtout considéré comme le passage d’une organisation soumise à une imago de mère phallique à un système où les deux parents jouent chacun un rôle spécifique ouvrant au développement du complexe d’Œdipe.
Visual Outcomes and Safety of a Small Diameter Intrastromal Refractive Inlay for the Corneal Compensation of Presbyopia
Authors: Bouzoukis Dimitrios I. , Kymionis George D. , Panagopoulou Sophia I. , Diakonis Vasilios F. , Pallikaris Aristophanes I. , Limnopoulou Aliki N. , Portaliou Dimitra M. , Pallikaris Ioannis G. 
Published: February 2012

PURPOSE:
To investigate the outcomes and safety of an intrastromal refractive inlay (Invue Lens, Biovision AG) for the corneal compensation of presbyopia.

METHODS:
This prospective, noncomparative, interventional clinical study comprised 45 emmetropic presbyopes with a mean age of 52.3±3.3 years (range: 47 to 58 years). The refractive inlay was inserted in the non-dominant eye within a corneal pocket that was created using a mechanical microkeratome. Last follow-up was 12 months in all patients and examinations were scheduled at 1 week and 1, 3, 6, and 12 months after surgery. Visual, wavefront, contrast sensitivity, and topographic outcomes as well as structural corneal alteration were evaluated.

RESULTS:
Twelve months after surgery, uncorrected near visual acuity was 20/32 or better in 98% of operated eyes and binocularly, whereas uncorrected distance visual acuity was 20/40 or better in 93% of operated eyes and 20/25 or better in all patients binocularly. Three patients lost one line of corrected distance visual acuity in the operated eye. Overall, higher order aberrations were increased and contrast sensitivity was decreased in the operated eye. No tissue alterations were found using corneal confocal microscopy. No intra- or postoperative complications occurred.

CONCLUSIONS:
The intracorneal refractive inlay (Invue Lens) seems to be an effective surgical method for the corneal compensation of presbyopia in emmetropes aged between 45 and 60 years.
Unilateral Sulcus Implantation of the Crystalens HD
Authors: Pallikaris Ioannis G. , Karavitaki Alexandra E. , Kymionis George D. , Kontadakis Georgios A. , Panagopoulou Sophia I. , Kounis George A. 
Published: February 2012

PURPOSE:
To evaluate the results after unilateral sulcus implantation of the Crystalens HD (Bausch & Lomb) accommodative intraocular lens (IOL).

METHODS:
This retrospective interventional case series comprised six eyes from three patients who underwent cataract surgery and bilateral Crystalens HD accommodative IOL implantation. The Crystalens HD was implanted in the bag in one eye (non-sulcus group) and, due to posterior capsule rupture, the lens was positioned in the ciliary sulcus in the fellow eye (sulcus group).

RESULTS:
Mean patient age was 66.3±4.9 years (range: 60 to 72 years). Mean follow-up was 14.3±3.2 months (range: 12 to 18 months) for the non-sulcus group and 14±2 months (range: 12 to 16 months) for the sulcus group. Uncorrected distance visual acuity improved from 20/100 to 20/33 in the non-sulcus group and from 20/63 to 20/32 in the sulcus group during last follow-up. Corrected distance visual acuity improved from 20/35 to 20/20 in the non-sulcus group and from 20/27 to 20/23 in the sulcus group. Regarding near vision, all eyes in the sulcus group and 66.7% of eyes in the non-sulcus group achieved J1–J2 (Birkhauser reading chart). None of the eyes had any intra- (except posterior capsule rupture in the sulcus cases) or postoperative complications.

CONCLUSIONS:
Based on this small series, ciliary sulcus implantation of the Crystalens HD seems to be associated with no significant morbidity and provides satisfactory visual acuity outcomes.
HER2/HER3 Signaling Regulates NK Cell-Mediated Cytotoxicity via MHC Class I Chain-Related Molecule A and B Expression in Human Breast Cancer Cell Lines
Authors: Okita Riki , Mougiakakos Dimitrios , Ando Takashi , Mao Yumeng , Sarhan Dhifaf , Wennerberg Erik , Seliger Barbara , Lundqvist Andreas , Mimura Kousaku , Kiessling Rolf 
Published: February 2012

Abstract
Overexpression of the receptor tyrosine kinases HER2 and HER3 is associated with a poor prognosis in several types of cancer. Presently, HER2- as well as HER3-targeted therapies are in clinical practice or evaluated within clinical trials, including treatment with mAbs mediating growth inhibition and/or activation of Ab-induced innate or adaptive cellular immunity. A better understanding of how HER2/HER3 signaling in tumors influences cellular immune mechanisms is therefore warranted. In this study, we demonstrate that HER2/HER3 signaling regulates the expression of MHC class I-related chain A and B (MICA and MICB) in breast cancer cell lines. The MICA and MICB (MICA/B) molecules act as key ligands for the activating receptor NK group 2, member D (NKG2D) and promote NK cell-mediated recognition and cytolysis. Genetic silencing of HER3 but not HER2 downregulated the expression of MICA/B, and HER3 overexpression significantly enhanced MICA expression. Among the major pathways activated by HER2/HER3 signaling, the PI3K/AKT pathway was shown to predominantly regulate MICA/B expression. Treatment with the HER3-specific ligand neuregulin 1β promoted the expression in a process that was antagonized by pharmacological and genetic interference with HER3 but not by the ataxia-telangiectasia–mutated (ATM) and ATM and Rad3-related protein kinases inhibitor caffeine. These observations further emphasize that HER2/HER3 signaling directly, and not via genotoxic stress, regulates MICA/B expression. As anticipated, stimulating HER2/HER3 enhanced the NKG2D-MICA/B–dependent NK cell-mediated cytotoxicity. Taken together, we conclude that signaling via the HER2/HER3 pathway in breast carcinoma cell lines may lead to enhanced NKG2D-MICA/B recognition by NK cells and T cells.