bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of biologic agents in rheumatoid arthritis: a bibliographic review
Authors: Juda Luiza Horta Barbosa 
Published: May 2024

Rheumatoid Arthritis (RA) is an autoimmune and chronic disease, which presents a heterogeneity of clinical manifestations and high potential for disability, consequently leading to a difficult diagnosis and treatment by health professionals. Common symptoms are pain, swelling, tenderness, warmth and redness in the affected joints, with long-term joint destruction, demonstrating the importance of early diagnosis and rapid initiation of treatment to prevent and control the pathogenic activity of the disease. Pharmacological treatment aims to mitigate and prevent joint damage, in addition to improving the patient's quality of life. Drug therapy varies according to the clinical stage and is based on the use of analgesics, corticosteroids, disease-modifying drugs, immunosuppressants and biologic agents. This article aims to address the treatment of RA, focusing on the use of biologic and targeted synthetic response modifiers and the best therapeutic choice, based on an integrative review with a survey of scientific data from 2017 to 2022, through guiding questions, based on of health data. The expected results include a synthetic and complete study of the treatment of RA and a thorough data analysis that in fact allows a better choice in the treatment of the disease.
Clinical audit on evaluating situations where patients are prescribed long-term steroids without appropriate monitoring for adverse effects such as osteoporosis, diabetes, or adrenal suppression
Authors: Abbas Waseem , Ahmed Aamir , Mehran Zoya , Ahmad Muhammad Saad , Khan Ahmad , Bukhari Syed Faraz , Ali Kashif , Ullah Sami , Lodhi Aiman Usman , Munawar Mehrub 
Published: May 2024

Chronic inflammatory diseases are better managed with long-term steroid therapy. Nevertheless, it predisposes the patient to numerous complications if not monitored properly. The current clinical audit was carried out at the Emergency Lady Reading Hospital to check on the adequacy of monitoring practices of prolonged steroid use. In particular, the study focused on preventing adverse effects such as osteoporosis, diabetes, and adrenal suppression, which remain significantly high but are largely unaddressed in many clinical settings. The audit focused on a 54-year-old male patient under treatment for chronic obstructive pulmonary disease and rheumatoid arthritis, who was managed under long-term prednisone therapy for 8 years. The patient presented symptoms as severe fatigue, muscle weakness, and bone pain, which could be interpreted as indicative of adrenal insufficiency and osteoporosis. These were once again confirmed by the diagnostic tests, which again revealed a very critical gap in monitoring and managing his steroid therapy. In this way, key recommendations include the need for periodic screening of bone density and adrenal function, and patient education on the risks of steroid use, it would be of great importance in ensuring the safety of patients and increasing the approaches to treatment to prevent these cases in the future.
Comparison between flexible ureteroscopy in pre-stented group of patients and none pre-stented patients
Authors: Allahyani Hossam , Alhayek Rafe , Akhtar Zeeshan 
Published: May 2024

Background: Ureteroscopy has a low re-treatment rate and a high stone-free rate, making it a very successful therapy for ureteral stones. Though ureteral stent installation may make ureteroscope and ureteral access sheath insertion easier, it may come with more complications before and after the procedure. Aim: The objective of the research was to examine the disparities between pre-stenting and non-presenting ureteroscopy in the management of ureteral stones. Summary: Preoperative implantation of a ureteral stent may somewhat reduce the duration of surgery and enhance the stone-free rates in individuals having flexible ureteroscopy (fURS), however the effect is not statistically significant. Preoperative stenting resulted in a longer hospital stay and higher hospital expenses, but did not affect the incidence of complications and re-operations. Based on these data, it may be concluded that it is not justifiable to perform preoperative ureteral stent implantation before fURS for the treatment of upper urinary calculi. Nevertheless, due to the constraints of our study, more rigorous research, such as prospective randomized clinical trials, is necessary to validate our results.
Innovative perspectives on the value of diagnostic tests in clinical practice
Authors: Kelly Estrada-Orozco , Cuervo Juliana 
Published: May 2024

Diagnostic tests have intrinsic characteristics such as sensitivity, specificity, overall accuracy and likelihood ratios which define their operational performance. It is not uncommon to find in the literature that test value and clinical utility are defined based exclusively on those characteristics. This paper introduces several arguments aimed at prompting a reflection regarding the characteristics that define the true value of diagnostic tests in clinical practice. It concludes with the view that the value of each diagnostic test needs to be established in accordance with the circumstances in which it is used, taking into account extrinsic characteristics such as in whom it is used, when, where and by who.
Capital social y desarrollo sostenible
Authors: Valadez Solana Brenda Dennís , Venegas Ríos Itzel Yolotzi , Cruz Domínguez Enrique , Cruz Cabrera Blasa Celerina 
Published: May 2024

Desde 1990, las investigaciones referentes al capital social (CS) y Desarrollo Sostenible (DS) han aumentado considerablemente debido a que el CS mejora las dimensiones del DS. El objetivo de este estudio es brindar un panorama bibliométrico de la literatura existente en los campos de CS y DS, a través de una visión cuantitativa. Los datos recopilados comprendieron el periodo de 1994-2022, con los conjuntos de datos de Scopus. Las unidades de análisis fueron revistas, países, instituciones, autores y publicaciones. Los métodos bibliométricos utilizados fueron el análisis de desempeño y el mapeo científico. El análisis de desempeño utilizó indicadores como el índice h, la productividad, el umbral de citas y las dimensiones de temporalidad. Para el mapeo científico se manejaron las técnicas de citas conjuntas y la co-ocurrencia de palabras clave; se crearon mapas de redes con el apoyo del software VOSviewer. Los resultados mostraron que Reino Unido es el país más productivo e influyente en publicaciones referentes a CS y DS. Los autores Ann Dale y Lenore Newman, fueron los más representativos. La sustentabilidad, el capital humano y los tipos de capital social: unión, puente y vertical, son los principales temas emergentes relacionados con el CS y DS.
Os riscos associados ao uso de anti-inflamatórios, e automedicação por idosos
Authors: Trindade Kaliane dos Santos , Deuner Melissa Cardoso , Santos Byanca Ruth Hellen Pereira dos 
Published: May 2024

O uso inapropriado e automedicação por idosos é uma prática comum, e a probabilidade de gerar consequências futura é enorme ocasionando no aumento de doenças e interações medicamentosas devido idosos que faz uso de medicamentos prescritos. Diante disso, o objetivo geral do trabalho foi compreender os riscos associados a automedicação entre a população idosa, na utilização de antiinflamatórios não esteroidais, e as reações adversas. Para isso, utilizou-se como metodologia a revisão de literatura, por meio da coleta de dados em bases como Scielo, Lilacs e Google Acadêmico. Os principais resultados obtidos com a pesquisa evidenciou que os idosos é a população que mais consomem os anti-inflamatórios, e que devem ser administrados com cautela, o uso indiscriminado dos AINES pode ocasionar efeitos indesejáveis utilizado sem acompanhamento farmacoterapêutica. Diante disso, o farmacêutico é o responsável capacitado na segurança e prevenção a prática do uso racional de medicamentos, ele vai além de fornecimento de medicamentos, o profissional esclarece ao paciente no uso inapropriado, e os riscos que podem ocorrer garantindo uma qualidade de vida a população.
THE ALGERIAN COMPETITION COUNCIL: A DE FACTO JURISDICTION
Authors: Mokeddem Toufik , Benturquia Linda Adiba 
Published: May 2024

Objective: The aim of this study is precisely to show and/or demonstrate the quasi-judicial character of the competition council, as a fully independent authority with all that it implies, particularly in terms of dealing with anti-competitive and/or restrictive practices of competition.

Method: To address the issue stated in this study, it seemed necessary to opt for an analytical research approach on all legal texts surrounding the relevance of the theme, and whenever necessary, to partially shift towards a comparative study between Algerian law (domestic law) and French law, notably to highlight certain similarities and/or specificities.

Result: The Algerian Competition Council is an autonomous administrative authority that acts on behalf and for the account of the State to enforce competition rules. It has legal personality and financial autonomy. It is placed under the Minister responsible for trade without being under their supervision. This all serves to confirm its absolute independence. Indeed, this authority is endowed with the power of sanction, with all that implies. Therefore, unquestionably, the Competition Council (without going through a competent jurisdiction de jure) sanctions restrictive or anti-competitive practices and settles disputes in this regard. In this context, the competition authority appears as an economic judiciary, distinguished by its own means, especially quasi-judicial ones: since the ability to impose sanctions, this imperium certainly gives it the character of a judiciary, or even a de facto jurisdiction: both in its form (referring to Delegating Jurisdiction to the Competition Council), and also in its content (referring to the "quasi-judicial" procedural process of administrative enforcement).
GITAR TUNGGAL LAMPUNG PESISIR: SEBUAH IDENTITAS DAN LANSKAP PENDIDIKAN MUSIK INFORMAL YANG BERBASIS KELOKALAN
Authors: Riyan Hidayatullah  
Published: May 2024

Gitar tunggal Lampung terdiri atas dua gaya, yakni pesisir dan pepadun. Diantara kedua gaya tersebut, peneliti melihat fakta-fakta unik yang terjadi pada gitar tunggal bergaya pesisir. Terdapat praktik sosial dan transmisi musik yang menonjolkan gaya ‘lokal.’ Gitar tunggal Lampung pesisir sebagai sebuah kesenian memiliki dua dimensi. Pertama, dimensi di mana musik itu dianggap sebagai musik pop daerah Lampung yang menyebar melalui ruang budaya massa. Kedua, gitar tunggal befungsi sebagai identitas musik dawai masyarakat Lampung pesisir. Sebelum gitar tunggal bergaya pesisir muncul dan dikonsumsi oleh masyarakat Lampung, musik gambus tunggal lebih dulu populer. Gitar tunggal bergaya pesisir mulai dikenal setelah Hila Hambala—salah seorang tokoh musik dawai Lampung—mulai mengonstruksi musik tersebut. Hila Hambala terinspirasi dengan permainan musik batanghari sembilan dari Sumatera Selatan. Selain itu Hila berusaha menggabungkan teknik petikan gambus tunggal dengan pola permainan batanghari sembilan.
Di dalam praktik sosial dan musikalnya, gitar tunggal Lampung pesisir juga ditularkan dengan proses transmisi musik secara informal. Masyarakat lokal umumnya mempelajari gitar tunggal di lingkungan keluarga, pertemanan, hingga masuk ke era digital. Hampir seluruh proses belajar itu terjadi secara mandiri melalui transkripsi musik yang menyesuaikan kondisi pemain. Meskipun proses belajar terjadi secara mandri dan informal, kenyataannya pola semacam itu efektif dan masih digunakan hingga saat ini. Praktik belajar musik itu juga dikenal dengan pola belajar improvisatoris, yakni sebuah pola pembelajaran yang menekankan pada otoritas pembelajar. Tidak ada kurikulum yang bersifat sistematis, karena proses belajar dilakukan secara mandiri dengan mengandalkan pemahaman dan kreativitas para pemain.
Gitar tunggal Lampung Pesisir dalam buku ini diposisikan sebagai objek material sedangkan esensi penulisannya lebih menekankan pada aspek pendidikan informal yang berbasis kelokalan (Lampung). Selain itu, penulis juga berusaha menguraikan lanskap musik dalam sudut pandang sosio-kultural yang memiliki bentuk, fungsi, dan nilai. Dengan sudut pandang dan gaya pemaparan dalam buku ini, diharapkan penulis dapat memberikan referensi lain tentang praktik pendidikan musik di masyarakat. Selama ini, studi pendidikan musik lebih banyak berfokus pada wilayah formal, sedangkan ruang informal cenderung lepas dari perhatian. Padahal, praktik penularan musik secara informal jumlahnya lebih banyak terjadi di lingkungan sekitar. Dengan memotret praktik pembelajaran dan transmisi musik, penulis berharap dapat memberikan wacana diskusi baru tentang pendidikan musik di Indonesia.
Las habilidades sociales en las competencias laborales de la figura profesional Comercialización y ventas
Authors: Aguilera-Proaño Rita Jacqueline , Criollo-Apolinario Ohanna Jacqueline , Campoverde-Moscol Amarilis Isabel 
Published: May 2024

La Educación y Formación Técnica y Profesional (EFTP), según la UNESCO, se centra en impartir conocimientos y habilidades prácticas relevantes para el mundo laboral. Esta formación se diferencia de otros tipos de educación al estar específicamente diseñada para preparar a los estudiantes para desempeñarse eficazmente en el ámbito laboral. La acelerada transformación de las sociedades y economías ha generado una crisis de valores, haciendo más relevante la incorporación de habilidades sociales en la educación. El objetivo de la investigación es determinar la incidencia de las habilidades sociales en la formación de competencias laborales en la figura profesional de Comercialización y Ventas. El estudio dimensiona las habilidades sociales e indaga sobre la comunicación asertiva, el trabajo en equipo, la toma de decisiones, la empatía y el autoconocimiento. En cuanto a las competencias laborales de la figura profesional, se indagaron las dimensiones de conocimiento y procedimiento. El proceso investigativo determinó como hipótesis que el desarrollo de las habilidades sociales fortalece la formación técnica profesional. La investigación desarrolló un enfoque cuantitativo no experimental con alcance descriptivo, correlacional y transeccional. El estudio se llevó a cabo en la Unidad Educativa Fiscal Juan Emilio Murillo Landín, ubicada en el cantón Guayaquil. Se aplicó un cuestionario de 12 ítem a la muestra seleccionada por conveniencia conformada por 29 estudiantes. Los resultados indican que los estudiantes están preparados para enfrentar desafíos laborales. Se propone continuar fortaleciendo estas habilidades y desarrollar actividades que promuevan el desarrollo integral de los estudiantes.
The Effect of Using Rebozo Technique during Labor on the Sensation of Labor Pain and Labor Duration
Authors: Uludağ Dilek Sinem , Ayar Kocatürk Asiye 
Published: May 2024

Background: Labor pain is one of the most severe pain types known and it is especially more intense in primiparous women. For this reason, this experimental study was conducted on the rebozo technique applied during labor in primiparous pregnant women to determine its effect on the perception of labor pain and labor duration.
Methods: This study was conducted between 1 July 2021 and 31 January 2022 in a private institution with two groups, 30 patients got treated with rebozo, rebozo group, 30 people in the control group, with a total of 60 patients. Data collection tools included patient information form, partograph form, Visual Analog Scale (VAS). Data was analysed with SPSS. Physical characteristics were similar (p>0.05).
Results: Application of Rebozo technique shortened the duration of the active phase of labor, the duration of the total active phase and the duration between the active phase and delivery. VAS score was found to be significantly lower with Rebozo technique application (p<0.05).
Conclusion: The study suggests that the rebozo technique is a reliable and effective method for reducing labor duration and pain sensation.
ОСОБЕННОСТИ ТЕЧЕНИЯ КАРДИОМИОПАТИЙ В ДЕТСКОМ ВОЗРАСТЕ
Authors: Шадиева Халима , Холикова Гулноз , Абдукадирова Наргиза 
Published: May 2024

Резюме. В статье рассматривается вопрос о клиническом течении различных форм кардиомиопатий (дилатационной, гипертрофической, рестриктивной) у детей. Полученные данные представляют интерес для врачей-кардиологов, врачей общей практики и педиатров семейных поликлиник.
Цель исследования: изучение особенностей клинического течения кардиомиопатий у детей, совершенствования тактики лечения для улучшения качества жизни и оптимизации прогноза.
Материал и методы. Было обследовано 36 детей в возрасте 0-17 лет. Среди обследованных частота различных форм кардиомиопатий составила: дилатационной - 61,1%, гипетрофической - 33,3%, рестриктивной – 5,6%. Изучены анамнестические данные, тяжесть течения, особенности ЭКГ, ЭхоКГ, рентгенографии при каждой из форм кардиомиопатии.
Результаты исследования. Возможно латентное, легкое, однако чаще среднетяжелое и тяжелое течение заболевания. Пациенты с ДКМП и ГКМП часто имеют различные нарушения ритма и проводимости. Показано диспансерное наблюдение и своевременная (непрерывная) терапия ХСН детям с кардиомиопатиями. При тяжелом течении ГКМП с обструктивными формами ГКМП рассматривается вопрос о хирургическом лечении.
La declaratoria judicial de unión de hecho post mortem en parejas LGBTIQ+ en el Ecuador. Un análisis del caso n°. 08201-2019-02570
Authors: Hessamzadeh Villamagua Seyedeh Sougand , Pinto Rodríguez Javier Alejandro , Vargas Secaira Raysa Gabriela , Jaramillo Viteri María José 
Published: May 2024

La presente investigación, tiene por objeto analizar la causa No. 08201-2019-2573, iniciada en la ciudad de Esmeraldas- Ecuador, a efectos de escudriñar las sentencias emitidas por la Jueza de primer nivel y el Tribunal de segunda instancia, así como la decisión adoptada por la Sala Especializada de la Familia, Niñez, Adolescencia y Adolescentes Infractores de la Corte Nacional de Justicia, respecto de una “Declaratoria de Unión de Hecho” entre dos personas (homosexuales), para lo cual se explora, la pretensión, las decisiones de instancia y el planteamiento realizado en sede casacional, donde se acusó falta de motivación de la sentencia emitida por el Tribunal de Apelación. Considerando que los fallos de primera y segunda instancia niegan la demanda, y dada la procedencia del recurso de casación planteado, en virtud del control de legalidad realizado, se estudia la unión de hecho como institución jurídica que regula las relaciones familiares paralelamente al matrimonio, como una expresión de la voluntad protegida por la ley, con sustento constitucional, y dado el contexto de este conflicto se pone en perspectiva la exclusión a la cual se enfrentan las parejas LGBTIQ+, al plantear este tipo de acciones, resueltas algunas veces por operadores de justicia, con sesgos parcializados, o desconocimiento de las normas nacionales e internacionales aplicables, como se evidencia en el fallo de primera instancia en este caso, determinándose además la profunda necesidad de capacitación permanente de los juzgadores en materia de género.
Features of the activities of the jury institute in the Volga region in the period from 1864 to 1917
Authors: Бойко Н.С. , Куликов А.В. 
Published: May 2024

осмысление и адаптация исторического опыта помогают избежать ошибок и негативных тенденций, которые свойственны эволюционным процессам развития гражданского общества при восприятии и внедрении различных моделей государственного устройства в период функционирования судов присяжных с 1864 г. по 1917 г. на территории Поволжских регионов, где данные суды были введены в систему судопроизводства рассматриваемого периода.
understanding and adaptation of historical experience helps to avoid mistakes and negative trends that are characteristic of the evolutionary processes of development of civil society when perceiving and implementing various models of government during the functioning of jury courts from 1864 to 1917 in the Volga regions, where these courts were introduced into the legal system of the period under review.
Melee weapons and defensive weapons of the nomads of Central Asia in the early Modern period
Authors: Панасюк Н.В. , Пастухов Д.А. 
Published: May 2024

статья посвящена изучению военного дела кочевников Центральной Азии в период раннего Нового времени. Целью работы является анализ отличительных особенностей комплекса вооружения кочевников в период раннего Нового времени. Задачами работы являются выявление характерных черт оружия ближнего боя и элементов защитной экипировки в исследуемый период. Анализируются вещественные, письменные и этнографические источники. Освещается вопрос типологизации клинкового, длиннодревкового, ударного и ударно рубящего оружия. Проводится анализ видов защитного вооружения, рассматриваются различные методы сборки панцирного доспеха, а также материалы изготовления подобной экипировки. Понимается вопрос боевых шлемов, наручей, поножей, набедренников и наплечников. Анализируются изменения в области применения как стационарных, так и ручных боевых щитов. Рассматриваются методы производства или приобретения кочевниками различных видов вооружения. Работа может стать основой или составной частью большого комплекса исследований в рамках изучения всего комплекса вооружения центральноазиатских кочевников на завершающем этапе своего самостоятельного развития. Также, на основании проведенного исследования возможна работа в области экспериментальной археологии, с созданием различных элементов вооружения и испытанием их тактико-технических характеристик.
the article is devoted to the study of the military affairs of the nomads of Central Asia in the early Modern period. The purpose of the work is to analyze the distinctive features of the nomad armament complex in the early Modern period. The objectives of the work are to identify the characteristic features of melee weapons and elements of protective equipment during the study period. The material, written and ethnographic sources are analyzed. The article highlights the issue of typologization of bladed, long-bladed, percussive and shock-chopping weapons. The analysis of types of protective weapons is carried out, various methods of assembling armored armor are considered, as well as materials for manufacturing such equipment. The issue of combat helmets, armbands, greaves, loincloths and shoulder pads is understood. The changes in the field of application of both stationary and manual combat shields are analyzed. The methods of production or acquisition of various types of weapons by nomads are considered. The work can become the basis or an integral part of a large complex of studies within the framework of studying the entire complex of weapons of Central Asian nomads at the final stage of their independent development. Also, based on the conducted research, it is possible to work in the field of experimental archaeology, with the creation of various elements of weapons and testing their tactical and technical characteristics.