bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel approach to runway overrun risk assessment using FRAM and flight data monitoring
Authors: Reiser C. , Villani E. , Machado Cardoso-Junior M. 
Published: May 2024

AbstractRunway overruns (ROs) are the result of an aircraft rolling beyond the end of a runway, which is one of the accident’s types that most frequently occurs on aviation. The risk of an RO arises from the synergistic effect among its precursors, such as unstable approaches, long touchdowns and inadequate use of deceleration devices. To analyse this complex socio-technical system, the current work proposes a customised functional resonance analysis method, called FRAM-FDM, as traditional techniques of risk and safety assessment do not identify the interactions and couplings between the various functional aspects of the system itself, especially regarding human and organisational components. Basically, FRAM-FDM is the coupling of a traditional FRAM with flight data monitoring (FDM) techniques, used here to quantify the variabilities of the flight crew performance while executing the required activity (i.e. the landing). In this proposal, these variabilities (i.e. the FRAM functions aspects) are aggregated by the addend of a logistic regression, resulting in a model to evaluate the flare operations and the brake application profile effect on the remaining distance to the end of the runway, used as a reference to classify the landing as acceptable or not. The present application of the FRAM-FDM assesses the operational risk of a sample fleet in overrunning the runway during landing, highlighting the brake pedal application profile as the most relevant contributor. The model improves the knowledge about the system behaviour, being useful to direct flight crew training.
Use of nonnative, invasive tree logs for commercial mushroom production
Authors: Bowers Kristen E. , Hight Stephen D. , Miller Neil W. , Gaffke Alexander M. , Taylor Jennifer E. 
Published: May 2024

AbstractRemoval and disposal of nonnative trees is expensive and time-consuming. Using these nonnative trees as a substrate to produce edible mushrooms could diversify farming operations and provide additional income to small-scale farmers. This research compared the production of shiitake mushrooms (Lentinula edodes) on nonnative tree logs to shiitake mushroom production on native oak (Quercus L.) logs, which are the traditional substrate. In a 2-yr study, we evaluated nonnative tree species as alternate substrates for growing shiitake mushrooms at farms in northern Florida and southern Georgia. A mix of native Quercus spp. and nonnative trees was targeted for removal on participating farms. Five nonnative tree species were initially tested for their ability to produce edible mushrooms, either shiitake or oyster (Pleurotus ostreatus var. florida). Of the nonnative trees we tested: Chinaberry (Melia azedarach L.), Chinese tallowtree [Triadica sebifera (L.) Small], silktree (Albizia julibrissin Durazz.), earleaf acacia (Acacia auriculiformis A. Cunn. ex Benth.), and paperbark tree [Melaleuca quinquenervia (Cav.) S.F. Blake], only T. sebifera produced shiitake mushrooms, and none produced native Florida oyster mushrooms. In on-farm trials, Quercus spp. logs produced more total mushrooms and more mushrooms per log and had a higher total mushroom yield per log. However, mushrooms produced on T. sebifera logs had higher mean weight per mushroom. Edible fungi can be used to recycle invasive, nonnative T. sebifera and transform their biomass from waste into an income-producing resource.
‘Microcosm of the Pacific’: Colonial encounters at the Central Medical School in Fiji
Authors: Cho Hohee 
Published: May 2024

AbstractWhile larger British colonies in Africa and Asia generally had their own medical services, the British took a different approach in the South Pacific by working with other colonial administrations. Together, colonial administrations of the South Pacific operated a centralised medical service based on the existing system of Native Medical Practitioners in Fiji. The cornerstone of this system was the Central Medical School, established in 1928. Various actors converged on the school despite its apparent isolation from global centres of power. It was run by the colonial government of Fiji, staffed by British-trained tutors, attended by students from twelve colonies, funded and supervised by the Rockefeller Foundation, and jointly managed by the colonial administrations of Britain, Australia, New Zealand, France and the United States. At the time of its establishment, it was seen as an experiment in international cooperation, to the point that the High Commissioner for the Western Pacific called it a ‘microcosm of the Pacific’. Why did the British establish an intercolonial medical school in Oceania, so far from the imperial metropole? How did the medical curriculum at the Central Medical School standardise to meet the imperial norm? And in what ways did colonial encounters occur at the Central Medical School? This article provides answers to these questions by comparing archival documents acquired from five countries. In doing so, this article will pay special attention to the ways in which this medical training institution enabled enduring intercolonial encounters in the Pacific Islands.
Within- and between-person associations of time-varying determinants with snacking in older adults: an ecological momentary assessment study
Authors: Cnudde Kim , De Vylder Flore , Cardon Greet , Maes Iris , Van Dyck Delfien 
Published: May 2024

AbstractPromoting healthy snacking is important in addressing malnutrition, overweight and obesity among an ageing population. However, little is known about the factors underlying snacking behaviour in older adults. The present study aimed to explore within- and between-person associations between determinants (i.e. intention, visibility of snacks, social modelling and emotions) and snacking behaviours (i.e. decision to snack, health factor of the snack and portion size) in older adults (60+). Conducting a two-part intensive longitudinal design, data were analysed from forty-eight healthy older adults consisting of (1) an event-based self-report ecological momentary assessment (EMA) diary every time they had a snack and (2) a time-based EMA questionnaire on their phone five times per day. Analysis through generalised linear mixed models indicated that higher intention to snack healthily leads to healthier snacking while higher levels of social modelling and cheerfulness promote unhealthier choices within individuals. At the between-person level, similar results were found for intention and social modelling. Visibility of a snack increased portion size at both a within- and between-person level, while the intention to eat a healthy snack only increased portion size at the between-person level. No associations were found between the decision to snack and all determinants. This is the first study to investigate both within- and between-person associations between time-varying determinants and snacking in older adults. Such information holds the potential for incorporation into just-in-time adaptive interventions, allowing for personalised tailoring, more effective promotion of healthier snacking behaviours and thus pursuing the challenge of healthy ageing.
A Retrospective Comparative Chart Review of Hearing Recovery in Neural and Sensory Type Sudden Sensorineural Hearing Loss Patients
Authors: Xu Rebecca Z. , Guo Ru C. , Wijesinghe Printha , Joshua Temitope G. , Ayub Aysha , Lee Melissa , Nunez Desmond A. 
Published: May 2024

AbstractObjectiveWhile the pathogenesis of sudden sensorineural hearing loss is thought to be localised to the cochlea, recent microRNA findings suggest a neuro-topic localisation in some patients. This study distinguishes if neural and non-neural groups differ in hearing recovery.MethodsNeural-type hearing loss was defined as a presenting word recognition score less than 60 per cent, with a word recognition score reduction greater than 20 per cent than expected based on the averaged pure tone audiometry. Hearing recovery was defined as an improvement of greater than or equal to 10 decibels in pure tone audiometric thresholds.ResultsEight of 12 and 24 of 36 of neural and non-neural hearing loss patients demonstrated hearing recovery, respectively. The affected ear's word recognition score (per cent) change with treatment were different between the neural and non-neural groups (46.9 ± 29.8 vs 3.2 ± 25.8 (p < 0.0001)).ConclusionThe hearing recovery rate in neural and non-neural hearing loss groups was similar. Patients with neural-type hearing loss demonstrated greater word recognition score recovery post treatment than those in the sensory group.
Why do citizens support algorithmic government?
Authors: Sidhu Dario , Magistro Beatrice , Allen Stevens Benjamin , Loewen Peter John 
Published: May 2024

AbstractAs governments increasingly adopt algorithms and artificial intelligence (AAI), we still know comparatively little about citizens’ support for algorithmic government. In this paper, we analyze how many and what kind of reasons for government use of AAI citizens support. We use a sample of 17,000 respondents from 16 OECD countries and find that opinions on algorithmic government are divided. A narrow majority of people (55.6%) support a majority of reasons for using algorithmic government, and this is relatively consistent across countries. Results from multilevel models suggest that most of the cross-country variation is explained by individual-level characteristics, including age, education, gender, and income. Older and more educated respondents are more accepting of algorithmic government, while female and low-income respondents are less supportive. Finally, we classify the reasons for using algorithmic government into two types, “fairness” and “efficiency,” and find that support for them varies based on individuals’ political attitudes.
Intraspecific karyotypic variability among 12 Indian accessions of Momordica charantia L. (bitter gourd): a medicinally important vegetable crop
Authors: Alam Md Mabud , Santra Indranil , Ghosh Biswajit 
Published: May 2024

AbstractBitter gourd is a highly nutritious vegetable and important medicinal plant of economic importance. The present study is focused on cytogenetical characterization of 12 accessions of bitter gourd from different parts of India, aiming to differentiate their karyotypes and outline diagnostic features of the chromosomes within each accession's haploid complement. All the accessions possess 2n = 22 numbers of chromosomes. The chromosomes mainly were metacentric (16‒22 chromosomes), and the presence or absence of sub-metacentric (0‒6 chromosomes) chromosomes. The length of the chromosomes varied from 0.83 to 1.93 μm among the accessions studied. Significant differences were obtained for the seven intra-chromosomal indices and four inter-chromosomal indices among the accessions. Principal component analysis and unweighted pair group method with arithmetic mean study revealed relatively distant positioning of individuals that advocated intraspecific phylogenetic relationships and higher karyoevolutionary affinity in bitter gourd accessions. In the meiotic study, regular meiotic behaviour indicates genetic stability and a stable sexual cycle in different accessions. The percentage of pollen viability of all the studied accessions was very high (89.41–94.11%), and these accessions can be considered to be good pollinators. The results obtained will guide characterizing the elite genotypes, genotypes management and designing effective breeding programmes and crop improvement programmes.
In Situ Determination of Thermoelastic Properties of Magnesite at High Pressure and Temperature With Implications to Seismic Detectability of Moderately Carbonated Lithologies in the Earth's Mantle
Authors: Xu Man , Jing Zhicheng , Van Orman James A. , Yu Tony , Wang Yanbin 
Published: May 2024

AbstractSubduction of carbonate‐bearing oceanic plates into Earth's interior recycles carbon from the surface to the deep mantle. The subducted carbonates can significantly affect mantle properties and dynamics. Magnesite is recognized as one of the major potential carbon hosts in the deep mantle because of its stability up to deep lower mantle conditions. However, despite many previous studies on the equation of state and elastic properties of magnesite, large discrepancies still exist for its elastic moduli and their pressure and temperature derivatives. Here we report in situ density and elastic wave velocity measurements on a natural magnesite at simultaneous high pressure‐temperature conditions up to ∼8 GPa–1073 K in a multi‐anvil apparatus using ultrasonic and synchrotron X‐ray techniques. Global fitting of the data set to finite strain equations yields KS0 = 114.0 ± 1.2 GPa, = 4.9 ± 0.3, = (−0.019 ± 0.002) GPa/K, G0 = 68.6 ± 0.4 GPa, G′ = 1.6 ± 0.1, and = (−0.018 ± 0.001) GPa/K. Compared to other major upper mantle and transition zone minerals, magnesite has intermediate VP, the lowest VS, and the lowest density. Thus, magnesite possesses higher VP/VS ratio than other mantle minerals in normal mantle regions, whereas this feature is less pronounced in subduction zone environments. Modeling of the velocity profiles of carbonated lithologies along different geotherms suggests that moderately‐enriched magnesite domains are unlikely to be detected seismically in the Earth's mantle.
Enhancing Soil Resilience to Climatic Wetting‐Drying Cycles Through a Bio‐Mediated Approach
Authors: Tang Chao‐Sheng , Liu Bo , Vahedifard Farshid , Jiang Ning‐Jun , Zhu Cheng , Shen Zheng‐Tao , Pan Xiao‐Hua , Cheng Qing , Shi Bin 
Published: May 2024

AbstractClimatic wetting‐drying cycles exacerbated by climate change can trigger several weakening mechanisms in surface soils, potentially leading to instability and failure of slopes and earthen structures. This study proposes a bio‐mediated approach based on microbially induced calcite precipitation (MICP) to increase soil resilience to wetting‐drying cycles. To explore its viability and the underlying mechanisms, we conducted a series of laboratory tests on clayey soil that underwent six wetting‐drying cycles. The tests were conducted with different treatment methods to investigate the effect of treatment sequence and cementation solution concentration. After MICP treatment, the initial evaporation rate, surface crack ratio during drying, and total soil weight loss during rainfall erosion were reduced by up to 32%, 85%, and 90%, respectively. Spraying the cementation solution first in the MICP treatment sequence proves more effective in improving soil water retention capacity. On the other hand, initiating the sequence with the bacterial solution demonstrates a more pronounced effect in reducing soil desiccation cracks and erosion. Microstructure analysis reveals that the content and distribution of CaCO3 precipitation are the major factors controlling the effectiveness of MICP for the cementation of clayey soil. Employing MICP can minimize the carbon footprint and contribute to developing environmentally friendly solutions for soil improvement in regions affected by climatic wetting‐drying cycles.
Improving MODIS Gross Primary Productivity by Bridging Big‐Leaf and Two‐Leaf Light Use Efficiency Models
Authors: Ma Yongming , Guan Xiaobin , Chen Jing Ming , Ju Weimin , Huang Wenli , Shen Huanfeng 
Published: May 2024

AbstractGross primary productivity (GPP) is an important component of the terrestrial carbon cycle in climate change research. The global GPP product derived using Moderate Resolution Imaging Spectroradiometer (MODIS) data is perhaps the most widely used. Unfortunately, many studies have indicated evident error patterns in the MODIS GPP product. One of the main reasons for this is that the applied big‐leaf (BL) MOD17 model cannot properly handle the variable relative contribution of sunlit and shaded leaves to the total canopy‐level GPP. In this study, we developed a model for correcting the errors in the MODIS GPP product by bridging BL and two‐leaf (TL) light use efficiency (LUE) models (CTL‐MOD17). With the available MODIS GPP product, which considers environmental stress factors, the CTL‐MOD17 model only needs to reuse the two inputs of the leaf area index (LAI) and incoming radiation. The CTL‐MOD17 model was calibrated and validated at 153 global FLUXNET eddy covariance (EC) sites. The results indicate that the modeled GPP obtained with the correction model matches better with the EC GPP than the original MODIS GPP product at different time scales, with an improvement of 0.07 in R2 and a reduction in root‐mean‐square error (RMSE) of 117.08 g C m−2 year−1. The improvements are more significant in the green season when the contribution of shaded leaves is larger. In terms of the global spatial pattern, the obvious underestimation in the regions with high LAI and the overestimation in the low LAI regions of the MODIS GPP product is effectively corrected by the CTL‐MOD17 model. This paper not only bridges the BL and TL LUE models, but also provides a new and simple method to obtain accurate GPP through reusing two inputs used in producing the MODIS GPP product.
Ionospheric Nowcasting Over Italy Through Data Assimilation: A Synergy Between IRI UP and IONORING
Authors: Pignalberi Alessio , Cesaroni Claudio , Pietrella Marco , Pezzopane Michael , Spogli Luca , Marcocci Carlo , Pica Emanuele 
Published: May 2024

AbstractAn accurate modeling of the ionosphere electron density is pivotal to guarantee the effective operation of communication and navigation systems, particularly during Space Weather events. Despite the crucial contribution of empirical models like the International Reference Ionosphere (IRI), their limitations in predicting ionospheric variability, especially under geomagnetically disturbed conditions, are acknowledged. The solution proposed in this work involves integrating real‐time, spatially distributed ionospheric measurements into climatological models through data assimilation. To enhance our predictive capabilities, we present an upgrade of the IRI UP data‐assimilation method, incorporating real‐time vertical total electron content (vTEC) maps from the IONORING algorithm for nowcasting ionospheric conditions over Italy. This approach involves updating the IRI F2‐layer peak electron density description through ionospheric indices, to finally produce real‐time maps over Italy of the ordinary critical frequency of the F2‐layer, foF2, which is crucial for radio‐propagation applications. The IRI UP–IONORING method performance has been evaluated against different climatological and nowcasting models, and under different Space Weather conditions, by showing promising outcomes which encourages its inclusion in the portfolio of ionospheric real‐time products available over Italy. The validation analysis highlighted also what are the current limitations of the IRI UP–IONORING method, particularly during nighttime for severely disturbed conditions, suggesting avenues for future enhancements.
Oxytocin, but not vasopressin, decreases willingness to harm others by promoting moral emotions of guilt and shame
Authors: Zheng Xiaoxiao , Wang Jiayuan , Yang Xi , Xu Lei , Becker Benjamin , Sahakian Barbara J. , Robbins Trevor W. , Kendrick Keith M. 
Published: May 2024

AbstractProsocial and moral behaviors have overlapping neural systems and can both be affected in a number of psychiatric disorders, although whether they involve similar neurochemical systems is unclear. In the current registered randomized placebo-controlled trial on 180 adult male and female subjects, we investigated the effects of intranasal administration of oxytocin and vasopressin, which play key roles in influencing social behavior, on moral emotion ratings for situations involving harming others and on judgments of moral dilemmas where others are harmed for a greater good. Oxytocin, but not vasopressin, enhanced feelings of guilt and shame for intentional but not accidental harm and reduced endorsement of intentionally harming others to achieve a greater good. Neither peptide influenced arousal ratings for the scenarios. Effects of oxytocin on guilt and shame were strongest in individuals scoring lower on the personal distress subscale of trait empathy. Overall, findings demonstrate for the first time that oxytocin, but not vasopressin, promotes enhanced feelings of guilt and shame and unwillingness to harm others irrespective of the consequences. This may reflect associations between oxytocin and empathy and vasopressin with aggression and suggests that oxytocin may have greater therapeutic potential for disorders with atypical social and moral behavior.
Celastrol ameliorates hypoxic-ischemic brain injury in neonatal rats by reducing oxidative stress and inflammation
Authors: Hu Yingying , Nan Yan , Lin Hongzhou , Zhao Qianlei , Chen Tingting , Tao Xiaoyue , Ding Bingqing , Lu Liying , Chen Shangqin , Zhu Jianghu , Guo Xiaoling , Lin Zhenlang 
Published: May 2024

Abstract

Background
Hypoxic-ischemic encephalopathy (HIE) is caused by perinatal hypoxia and subsequent reductions in cerebral blood flow and is one of the leading causes of severe disability or death in newborns. Despite its prevalence, we currently lack an effective drug therapy to combat HIE. Celastrol (Cel) is a pentacyclic triterpene extracted from Tripterygium Wilfordi that can protect against oxidative stress, inflammation, and cancer. However, whether Cel can alleviate neonatal hypoxic-ischemic (HI) brain damage remains unclear.

Methods
Here, we established both in vitro and in vivo models of HI brain damage using CoCl2-treated PC12 cells and neonatal rats, respectively, and explored the neuroprotective effects of Cel in these models.

Results
Analyses revealed that Cel administration reduced brain infarction size, microglia activation, levels of inflammation factors, and levels of oxidative stress markers by upregulating levels of p-AMPKα, Nrf2, HO-1, and by downregulating levels of TXNIP and NLRP3. Conversely, these beneficial effects of Cel on HI brain damage were largely inhibited by AMPKα inhibitor Compound C and its siRNA.

Conclusions
We present compelling evidence that Cel decreases inflammation and oxidative stress through the AMPKα/Nrf2/TXNIP signaling pathway, thereby alleviating neonatal HI brain injury. Cel therefore represents a promising therapeutic agent for treating HIE.

Impact

We firstly report that celastrol can ameliorate neonatal hypoxic-ischemic brain injury both in in vivo and in vitro, which represents a promising therapeutic agent for treating related brain injuries.

Celastrol activates the AMPKα/Nrf2/TXNIP signaling pathway to relieve oxidative stress and inflammation and thereby alleviates neonatal hypoxic-ischemic brain injury.