bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dealing with callers’ racialised talk in suicide preventive helplines: Accomplishing (anti)racism in the context of unconditional support
Authors: Iversen Clara , Flinkfeldt Marie , Hamed Sarah 
Published: June 2024

AbstractThis article investigates how mental health counsellors on helplines in Sweden deal with racism from callers who self‐categorise as non‐racialised. Previous studies have identified racism as a problem in health care interactions, but there is limited knowledge about the features of racialised talk and how staff respond. In this study, we use conversation analysis and membership categorisation analysis to examine racialised talk in 17 audiorecorded calls, a subset of 458 calls to suicide preventive helplines. The analysis shows that racialisation functions as a resource for callers to make sense of their mental health difficulties. This speaks to the complexity of responding to racism in a mental health setting, as counsellors must see to callers’ needs, and calling out racialised talk may alienate callers. Call‐takers manage this problem in three ways: (1) questioning racialised talk, (2) supporting the callers’ stance in a way that makes it ambiguous if call‐takers are coproducing racism or affiliating with callers’ lives being difficult and (3) supporting callers’ problems as mental health issues while resisting a potentially racist trajectory. The study offers direct insight into the workings of racism in health care and how practitioners can balance health care users' needs for support with an antiracist position.
Maternal morbidity and death associated with pregnancy loss before 28 weeks in Nigeria
Authors: Etuk Saturday J. , Orazulike Ngozi , Abasiattai Aniekan M. , Omo‐Aghoja Lawrence O. , Njoku Anthonia , Ande Adedapo B. , Uwagboe Charles , Igbarumah Solomon , Ibrahim Isa Ayuba , Ekpebe Patrick , Ochigbo Sunny , Nyong Eno Etim , Ibeawuchi Amarabia , Idemudia Ebe , Okagua Joyce , Eigbedion Andrew , Ezekwe Bose , Adeyemi Oyedeji Oladele , Lavin Tina , Tukur Jamilu 
Published: June 2024

AbstractObjectiveTo determine the prevalence of maternal morbidity and death from pregnancy loss before 28 weeks in referral‐level hospitals in Nigeria.DesignSecondary analysis of a nationwide cross‐sectional study.SettingFifty‐four referral‐level hospitals.PopulationWomen admitted for complications arising from pregnancy loss before 28 weeks between 1 September 2019 to 31 August 2020.MethodsFrequency and type of pregnancy loss were calculated using the extracted data. Multilevel logistic regression was used to determine sociodemographic and clinical factors associated with early pregnancy loss. Factors contributing to death were also analysed.Main outcome measuresPrevalence and outcome of pregnancy loss at <28 weeks; sociodemographic and clinical predictors of morbidity after early pregnancy loss; contributory factors to death.ResultsOf the 4798 women who had pregnancy loss at <28 weeks of pregnancy, spontaneous abortion accounted for 49.2%, followed by missed abortion (26.9%) and ectopic pregnancy (15%). Seven hundred women (14.6%) had a complication following pregnancy loss and 99 women died (2.1%). Most complications (26%) and deaths (7%) occurred after induced abortion. Haemorrhage was the most frequent complication in all types of pregnancy loss with 11.5% in molar pregnancy and 6.9% following induced abortion. Predictors of complication or death were low maternal education, husband who was not gainfully employed, grand‐multipara, pre‐existing chronic medical condition and referral from another facility or informal setting.ConclusionPregnancy loss before 28 weeks is a significant contributor to high maternal morbidity and mortality in Nigeria. Socio‐economic factors and delays in referral to higher levels of care contribute significantly to poor outcomes for women.
Examining early adherence measures as predictors of subsequent adherence in an intensive longitudinal study of individuals in mutual help groups: One day at a time
Authors: McCool Matison W. , Schwebel Frank J. , Pearson Matthew R. , Tonigan J. Scott 
Published: June 2024

AbstractBackgroundIndividuals with a substance use disorder complete ecological momentary assessments (EMA) at lower rates than community samples. Previous research in tobacco users indicates that early log‐in counts to smoking cessation websites predicted subsequent smoking cessation website usage. We extended this line of research to examine individuals who are seeking to change their drinking behaviors through mutual support groups. We examined whether adherence in the first 7 days (1487 observations) of an intensive longitudinal study design could predict subsequent EMA protocol adherence (50% and 80% adherence separately) at 30 (5700 observations) and 60 days (10,750 observations).MethodsParticipants (n = 132) attending mutual‐help groups for alcohol use completed two assessments per day for 6 months. We trained four classification models (logistic regression, recursive partitioning, support vector machines, and neural networks) using a training dataset (80% of the data) with each of the first 7 days' cumulative EMA assessment completion. We then tested these models to predict the remaining 20% of the data and evaluated model classification accuracy. We also used univariate receiver operating characteristic curves to examine the minimal combination of days and completion percentage to best predict subsequent adherence.ResultsDifferent modeling techniques can be used with early assessment completion as predictors to accurately classify individuals that will meet minimal and optimal adherence rates later in the study. Models ranged in their performance from poor to outstanding classification, with no single model clearly outperforming other models.ConclusionsTraditional and machine learning approaches can be used concurrently to examine several methods of predicting EMA adherence based on early assessment completion. Future studies could investigate the use of several algorithms in real time to help improve participant adherence rates by monitoring early adherence and using early assessment completion as features in predictive modeling.
Global association of secondhand smoke exposure locations and smoking behaviour among adolescents in 99 countries
Authors: Hong Seohyun , Son Yejun , Lee Hyeri , Kim Soeun , Kim Hyeon Jin , Jo Hyesu , Park Jaeyu , Lee Kyeongmin , Lee Hayeon , Dragioti Elena , Fond Guillaume , Boyer Laurent , López Sánchez Guillermo F. , Tully Mark A. , Rahmati Masoud , Smith Lee , Kim Sunyoung , Woo Selin , Yon Dong Keon 
Published: June 2024

AbstractAimThis study classified 99 countries into four income groups and then analysed the impact of secondhand smoke (SHS) exposure at home, in public places and at school, on current cigarette smoking prevalence.MethodsWe utilised data from the WHO Global Youth Tobacco Survey and a meta‐analysis was conducted to evaluate the prevalence and weighted odds ratios (wORs) of adolescent smoking behaviour and SHS exposure locations.ResultsBoth smoking behaviours increased with higher national income levels. Smoking behaviours in high and upper‐middle‐income countries (HICs and UMICs) exhibited an association with SHS exposure in public places (HIC: wOR, 3.50 [95% CI, 2.85–4.31]; UMIC: wOR, 2.90 [2.60–3.23]) compared to home. Low‐ and lower‐middle‐income countries (LICs and LMICs) showed an association with SHS exposure in the home (LIC: wOR, 5.33 [3.59–7.93]; LMIC: wOR, 2.71 [2.33–3.17]) than public places. The association between current cigarette smoking and SHS exposure at home increased with lower income levels, while anticipated future use of any form of tobacco with SHS exposure in public places rose in lower income countries.ConclusionsTargeted interventions based on income levels are essential, emphasising home strategies in lower income countries and public place efforts in higher income countries.
Study on the mechanism of quercetin in Sini Decoction Plus Ginseng Soup to inhibit liver cancer and HBV virus replication through CDK1
Authors: Hao Liyuan , Li Shenghao , Chen Guo , Nie Aiyu , Zeng Liang , Xiao Zhonghui , Hu Xiaoyu 
Published: June 2024

AbstractBackgroundTo explore the anti‐tumor and anti‐virus key active ingredients of Sini Decoction Plus Ginseng Soup (SNRS) and their mechanisms.MethodsThe main ingredients of SNRS were analyzed by network pharmacology, and quercetin was identified as the key active ingredient. Then, we obtained the targets of quercetin by using Drugbank, PharmMapper, and SwissTargetPrediction databases. Then, the targets of HBV‐related hepatocellular carcinoma (HBV‐related HCC) were obtained by using Genecards database. In addition, using the gene expression profiles of HBV‐related HCC patients in GEO database and the genes with the greatest survival difference in GEPIA 2 database identified the potential targets of quercetin. In addition, the mechanism of potential genes was studied through GO, KEGG analysis, and PPI network. Using AUC and survival analysis to evaluate the diagnostic and prognostic value of cyclin‐dependent kinase 1 (CDK1) and CCNB1. Finally, the effects of quercetin on proliferation of Hep3B and HepG2215 cells and the level of CDK1 and CCNB1 were verified in vitro. ELISA was used to measure the expression levels of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) after the intervention by quercetin for 24 h and 48 h in HepG2215 cell.ResultsThe first 10 key ingredients of SNRS were identified, and quercetin was the most key ingredient. The 101 potential quercetin targets were identified for the treatment of HBV‐related HCC. GO and KEGG showed that 101 potential target enrichment in cancer and cell cycle regulation. By Venn analysis, CDK1 and CCNB1 were intersection targets, which could be used as potential targets for the action of quercetin on HBV‐related HCC. Moreover, the expression of CDK1 and CCNB1 was highly expressed in the high‐risk group, while the OS rate was low. The 1‐year, 3‐year and 5‐year area under the curve (AUC) curves of CDK1 and CCNB1 were 0.724, 0.676, 0.622 and 0.745, 0.678, 0.634, respectively. Moreover, experimental results also showed that quercetin inhibited cell proliferation and reduced CDK1 expression in Hep3B and HepG2215 cells. The expressions of HBsAg and HBeAg in HepG2215 cell supernatant and cell gradually decreased with the increase of intervention time of quercetin and CDK1 inhibitor.ConclusionsQuercetin is a key ingredient of anti‐HBV‐related HCC activity and inhibits HBV replication in SNRS by inhibiting CDK1.
Non‐dilated left ventricular cardiomyopathy with arrhythmias is commonly caused by the nonsense variant DSP:c.3793G>T in Slovenian patients
Authors: Vodnjov Nina , Zupan Mežnar Anja , Maver Aleš , Dolinšek Ajda , Peterlin Borut , Writzl Karin 
Published: June 2024

AbstractDSP‐cardiomyopathy has recently been recognised as a specific type of cardiomyopathy. Using an in‐house Mendelian disease registry, we aimed to identify probands with likely pathogenic or pathogenic DSP variants. We detected these variants in 4.8% and 77.8% of genotype‐positive probands referred for dilated and non‐dilated left ventricular cardiomyopathy (NDLVC), respectively. We identified six Slovenian probands with the DSP:c.3793G>T and characterised them along with further eight of their relatives at the molecular and phenotypic level. Medical records revealed NDLVC with arrhythmia in six individuals (five probands, one relative; 33 ± 14 years; three males, three females). All had subepicardial late gadolinium enhancement on cardiac MRI (CMRI), and five received an ICD. Four individuals (one proband, three relatives; 48 ± 14 years; all female) had no ECG and/or cardiac abnormalities on CMRI detected. Our analysis presents a Slovenian‐specific molecular pathology of DSP cardiomyopathy, delineates the clinical manifestation of DSP:c.3793C>T, and thereby improves the understanding of the clinical outcomes associated with truncating DSP variants.
Clinical and radiographic outcomes of implant‐supported fixed prostheses with cantilever extension in anterior mandible: A retrospective study
Authors: Wang Siyuan , Chen Xiaoyu , Ling Zhaoting , Xie Yiwen , Chen Cong , Shen Xiaoting , He Fuming 
Published: June 2024

AbstractObjectivesThe objective of this study is to analyze the clinical and radiographic outcomes of implant‐supported fixed protheses with cantilever extensions (ISFPCs) in the partially edentulous anterior mandible.Materials and MethodsPatients who received anterior mandible implant restoration between January 2016 and December 2021 were included. Patients with two, three, or four continuous missing teeth receiving adjacent implant supported single‐unit crowns (ISSCs), ISFPCs, implant‐supported fixed protheses without cantilever extensions (ISFPNs) were divided into groups: ISSC+ISSC, ISFPC, ISSC+ISFPC, three‐unit ISFPN, ISFPC+ISFPC, or four‐unit ISFPN, respectively. We recorded and evaluated survival rates, mechanical and biological complications, peri‐implant marginal bone loss (MBL), esthetic outcomes, and patient perceptions. Statistical analysis was performed using linear mixed models (LMM).ResultsThe study included 87 patients and 152 implants. No implant loss occurred during an average follow‐up of 3.48 ± 1.85 years (range: 1–7 years). According to LMM models, prosthetic type had a statistically significant impact on MBL during follow‐up periods, in favor of the ISFPC and ISFPC+ISFPC groups (0.16 ± 0.48 mm vs. 0.51 ± 0.49 mm, p = .034; 0.22 ± 0.49 mm vs. 0.60 ± 0.62 mm, p = .043, respectively). Mechanical and biological complications were relatively low and comparable. The four‐unit ISFPC group had higher subjective esthetic scores compared with the ISSC+ISSC group (98.6 vs. 83.8, p < .05), and patients in the ISFPC+ISFPC group expressed greater satisfaction with cleanability than the ISFPN group (98.8 vs. 80.6).ConclusionISFPCs offer a highly predictable treatment option in the anterior mandible, characterized by high survival rates, and comparable complication rates, peri‐implant bone stability and esthetics to adjacent ISSCs or ISFPNs.
Islamic faith‐based organisations and their role in building social capital for post‐disaster recovery in Indonesia
Authors: Nurdin Muhammad Riza 
Published: June 2024

AbstractThis paper investigates the role of Islamic faith‐based organisations (FBOs) in Indonesia and examines the way in which their disaster recovery aid can be successful or less successful depending on social capital formation in communities affected by a disaster. The paper argues that Islamic FBOs play a prominent role in disaster‐affected communities by building new social capital or strengthening existing social capital. Failure to do so may affect a community's recovery and its long‐term resilience. Applying a framework that considers three types of social capital—bonding, bridging, and linking—from a comparative perspective, the paper discusses two cases of disaster recovery: one following the earthquake that struck Aceh in 2013; and the other after the Mount Kelud volcanic eruptions in East Java in 2014. In both instances, the findings highlight the importance of the village facilitator, cultural sensitivity, and understanding of local indigenous and religious practices for successful disaster recovery.
Key results from observational studies and real‐world evidence of sodium‐glucose cotransporter‐2 inhibitor effectiveness and safety in reducing cardio‐renal risk
Authors: Nyström Thomas 
Published: June 2024

AbstractSodium‐glucose cotransporter 2 (SGLT2) inhibitors, originally designed to manage blood sugar levels in individuals with type 2 diabetes (T2D), have emerged as a crucial class of drugs for managing cardio‐renal diseases. These drugs work by targeting the SGLT2 protein in the kidneys, promoting the excretion of glucose and influencing metabolic pathways beyond glucose control. The relationship between cardio‐renal diseases and SGLT2 inhibitors has been explored through landmark trials and real‐world evidence (RWE) studies, demonstrating significant reductions in cardio‐renal complications. This review discusses the importance of RWE studies alongside randomized controlled trials in understanding the real‐world effectiveness and safety of SGLT2 inhibitors. It outlines the advantages and disadvantages of RWE compared to RCTs, highlighting their complementary roles in providing comprehensive insights into treatment outcomes. By examining a range of RWE studies, the review underscores the cardio‐renal benefits of SGLT2 inhibitors across various patient populations. Safety assessments indicate that SGLT2 inhibitors are generally well tolerated, with severe adverse events being rare. Common issues, such as genital mycotic infections and urinary tract infections, are acknowledged, alongside less frequent but significant adverse events including diabetic ketoacidosis, lower‐limb amputations, and bone fractures. In summary, SGLT2 inhibitors show promising cardio‐renal protective effects in real‐world scenarios across diverse populations in T2D, indicating their potential as early intervention measures. Continued research is essential for gaining a thorough understanding of their long‐term effects and safety profiles.
The how and how much of technology use in the classroom: A motivational approach to teachers' technology use
Authors: David Loukia , Weinstein Netta 
Published: June 2024

AbstractTechnology in the classroom can facilitate learning, but little is known about how the motivational climate set by teachers shapes its impacts on students. Informed by self‐determination theory, the current study explored technology use in English language classrooms to understand how autonomy‐supportive and structured teaching styles influenced positive outcomes of classroom technology use. Teachers (N = 101) reported on technology use and motivational styles, and students (N = 550) aged 9–16 years reported on basic psychological needs satisfaction (autonomy, relatedness and competence) and academic well‐being (interest and effort). Findings of nested models showed no direct benefits for the amount of technology use; more autonomous teaching style and low structure linked to students' need satisfaction and interest. Beyond these main effects, when teachers were more autonomous, using technology enhanced student need satisfaction and interest; the combination of both was most beneficial for these student outcomes. Counter to expectations, when teachers had low structure technology use enhanced their impact on students. Findings suggest that to optimize student well‐being and interest in learning, teachers benefit from combining autonomy‐supportive education styles and technology use.
Enhancing education quality: Exploring teachers' attitudes and intentions towards intelligent MR devices
Authors: Chen Yuyu , Zou Yuntao 
Published: June 2024

AbstractThis research paper focuses on the adoption of multi‐perspective theory to study teachers' attitudes and intentions towards using intelligent mixed reality (MR) devices for classroom behaviour analysis. The research model integrates TRI (Technology Readiness Index), IDT (Innovation Diffusion Theory), ECM (Expectation Confirmation Theory) and TAM (Technology Acceptance Model) model. The variable of insecurity is considered to address the concerns regarding information security in the use of artificial intelligence in education. The study identifies that innovation and relative advantage significantly and positively influence teachers' attitudes towards using intelligent MR devices. PeoU (perceived ease of use), however, does not have a significant impact on attitudes, suggesting that teachers prioritize the benefits of enhancing teaching quality over the complexity of the devices. PU (perceived usefulness) emerges as a key variable for teachers' adoption of intelligent MR devices, prompting the need for attention from designers and manufacturers. Regression analysis reveals that gender does not influence the use of new technology, while teachers with more teaching experience and those working in remote areas express greater receptiveness towards utilizing new technology. The paper recognizes the potential of intelligent teaching devices to address educational challenges and promote equity in remote areas by providing auxiliary tools for teachers to improve teaching efficiency and quality. Teacher training and technical support are emphasized as crucial factors for effective use of artificial intelligence teaching devices.
Predicting international student satisfaction in Chinese universities: A comparison between undergraduate and graduate students
Authors: Zhao Kai , Ma Jiani 
Published: June 2024

AbstractWith the rapid growth in the number of international students coming to China, improving the quality and effectiveness of international student education has become a new policy priority. This study investigates the quality issue from the perspective of student satisfaction, with a focus on how satisfaction varies by academic level. We analysed data from a national survey involving 1,322 international students studying at Chinese colleges and universities using ordered logit regression models. The results indicate that most international students are satisfied with the host institutions. Both individual and environmental factors are significantly associated with the level of student satisfaction and these associations are different among undergraduate and graduate students. These findings underscore the importance of tailoring support to meet the distinct needs of students at different academic stages and suggest that universities can enhance student satisfaction by fostering a supportive interpersonal environment.
Connecting the dots: Sensory cueing enhances functional connectivity between pre‐motor and supplementary motor areas in Parkinson's disease
Authors: Zadeh Ali K. , Sadeghbeigi Narges , Safakheil Hosein , Setarehdan Seyed Kamaledin , Alibiglou Laila 
Published: June 2024

AbstractPeople with Parkinson's disease often exhibit improvements in motor tasks when exposed to external sensory cues. While the effects of different types of sensory cues on motor functions in Parkinson's disease have been widely studied, the underlying neural mechanism of these effects and the potential of sensory cues to alter the motor cortical activity patterns and functional connectivity of cortical motor areas are still unclear. This study aims to compare changes in oxygenated haemoglobin, deoxygenated haemoglobin and correlations among different cortical regions of interest during wrist movement under different external stimulus conditions between people with Parkinson's disease and controls. Ten Parkinson's disease patients and 10 age‐ and sex‐matched neurologically healthy individuals participated, performing repetitive wrist flexion and extension tasks under auditory and visual cues. Changes in oxygenated and deoxygenated haemoglobin in motor areas were measured using functional near‐infrared spectroscopy, along with electromyograms from wrist muscles and wrist movement kinematics. The functional near‐infrared spectroscopy data revealed significantly higher neural activity changes in the Parkinson's disease group's pre‐motor area compared to controls (p = 0.006), and functional connectivity between the supplementary motor area and pre‐motor area was also significantly higher in the Parkinson's disease group when external sensory cues were present (p = 0.016). These results indicate that external sensory cues' beneficial effects on motor tasks are linked to changes in the functional connectivity between motor areas responsible for planning and preparation of movements.