bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intracranial Aneurysms Managed by Parent Artery Reconstruction Using Tubridge Flow Diverter study: 1-year outcomes
Authors: Li Qiang , Lv Nan , Li Li , Gu Yuxiang , Xu Liquan , Lv Ming , Huang Changren , Mao Guohua , Lu Hua , Zhong Shu , Duan Chuanzhi , Xie Xiaodong , Wan Jieqing , Wang Feng , Guan Sheng , Zhao Rui , Dai Dongwei , Zhou Yu , Huang Qinghai , Xu Yi , Miao Zhongrong , Li Tianxiao , Liu Jianmin 
Published: June 2024

OBJECTIVE
Previous randomized controlled trials have reported a significantly higher occlusion rate of large and giant aneurysms when utilizing the Tubridge flow diverter (FD). In the present trial, the safety and efficacy of the Tubridge FD in treating unruptured internal carotid artery (ICA) or vertebral artery (VA) aneurysms were assessed in a real-world setting.

METHODS
The Intracranial Aneurysms Managed by Parent Artery Reconstruction Using Tubridge Flow Diverter (IMPACT) study is a prospective, multicenter, single-arm clinical trial assessing the efficacy of the Tubridge FD in the management of unruptured aneurysms located in the ICA or VA. The primary endpoint was the complete occlusion (Raymond-Roy class 1) rate at the 1-year follow-up. The secondary endpoints included the technical success rate, the successful occlusion rate of the aneurysm, which is the degree of aneurysm embolization scored as Raymond-Roy class 1 or 2, major (> 50%) in-stent stenosis, and incidence of disabling stroke or neurological death associated with the target aneurysms.

RESULTS
This study included 14 interventional neuroradiology centers, with 200 patients and 240 aneurysms. According to angiographic core laboratory assessment, 205 (85.4%) aneurysms were located in the ICA, 34 (14.2%) in the VA, and 1 (0.4%) in the middle cerebral artery. Additionally, 189 (78.8%) aneurysms were small (< 10 mm). At the 12-month follow-up, the total occlusion rate was 79.0% (166/210, 95% CI 72.91%–84.34%). Additionally, the occurrence of disabling stroke or neurological death related to the specified aneurysms was 1% (2/200).

CONCLUSIONS
The 1-year results from the IMPACT trial affirm the safety record of use of the Tubridge FD in the treatment of intracranial aneurysms in real-world scenarios. These results reveal low morbidity and mortality rates of 3.5% and 1.5%, respectively. Furthermore, they provide evidence of the effectiveness of the Tubridge FD, as demonstrated by the complete occlusion achieved in 166 of 210 (79%) cases.
Endoscopic transorbital approach to the petrous apex: is orbital rim removal worthwhile for the exposure? An anatomical study with illustrative case
Authors: Hong Chang-Ki , Mosteiro Alejandra , Kong Doo-Sik , Tafuto Roberto , Codes Marta , Ferres Abel , Matas Jessica , Manfrellotti Roberto , Prats-Galino Alberto , Di Somma Alberto , Enseñat Joaquim 
Published: June 2024

OBJECTIVE
The endoscopic transorbital approach (ETOA) has been demonstrated to be a feasible ventral route to the petrous apex. Yet, it has been pointed to as a deep and narrow corridor for anterior petrosectomy; particularly, medialization of the instruments can become an issue when targeting the petroclival area. To overcome this limitation, an ETOA with orbital rim removal (ETOA-OR) has been suggested, but not de facto compared, with a transorbital approach without removal of the rim. This addition could augment the surgical exposure and freedom of movement when accessing the petrous apex area.

METHODS
Five human cadaveric heads (10 sides) were dissected. First, anterior petrosectomy was performed via a conventional ETOA (without orbital rim removal). Second, en bloc removal of the orbital rim was performed, with enlargement of the orbital craniectomy and, subsequently, further drilling of the medial petrous apex. Qualitative and quantitative comparisons are provided. An illustrative surgical case is also shown.

RESULTS
The transorbital route allowed the authors to perform an anterior petrosectomy in all specimens. The landmarks of bone removal are superposed onto those in the transcranial route. The ETOA-OR increased the volume of craniectomy (from 4.0 mL to 5.5 mL), the lateromedial angulation, and superoinferior angulation of the instruments within the petrous area. Thus, this approach improved the exposure of the medial petroclival area, allowing for an augmented petrosectomy (from 1.4 mL to 2.0 mL, 39.5% increase) and for increased maneuverability, both in the petrous area (from 44.1 cm2 to 76.5 cm2, 73.3% increase) and in the posterior fossa (from 20.2 cm2 to 52.0 cm2, 158% increase). The ETOA-OR was also pragmatically applied to treat a recurrent petroclival meningioma. Complete removal was achieved, the abducens nerve palsy improved, and the trigeminal neuralgia decreased in severity, yet still required medication.

CONCLUSIONS
The authors provide the first formal anatomical comparison between the transorbital approach with preservation of the orbital rim and a transorbital approach with removal of the rim to access the petrous apex. In addition, an illustrative case is used as a proof of concept and feasibility. According to the authors’ data, the ETOA-OR significantly improves surgical exposure and the surgeon’s comfort in this deep region. The bony defect can be reconstructed to avoid cosmetic deformities, maintaining the minimally disruptive concept of transorbital surgery.
Stereotactic radiosurgery for prostate cancer spine metastases: local control and fracture risk using a simultaneous integrated boost approach
Authors: Beckham Thomas H. , Rooney Michael K. , Cifter Gizem , Bernard Vincent , McAleer Mary Frances , De Brian S. , Tom Martin C. , Perni Subha , Wang Chenyang , Swanson Todd , Tatsui Claudio E. , Alvarez-Breckenridge Christopher , North Robert , Rhines Laurence D. , Tang Chad , Logothetis Christopher , Amini Behrang , Li Jing , Yeboa Debra N. , Ghia Amol J. 
Published: June 2024

OBJECTIVE
Variation exists in approaches to delivery of spine stereotactic radiosurgery (SSRS). Here, the authors describe outcomes following single-fraction SSRS performed using a simultaneous integrated boost for the treatment of prostate cancer spine metastases.

METHODS
Health records of patients with prostate cancer spine metastases treated with single-fraction SSRS at the authors’ institution were reviewed. Treatment was uniform, with 16 Gy to the clinical tumor volume and 18 Gy to the gross tumor volume. The primary endpoint was local recurrence, with secondary endpoints including vertebral fracture and overall survival. Univariate and multivariate competing risk regression models made using the Fine and Gray method were used to identify factors predictive of local recurrence, considering death to be a competing event for local recurrence.

RESULTS
A total of 87 targets involving 108 vertebrae in 68 patients were included, with a median follow-up of 22.5 months per treated target. The 1-, 2-, and 4-year cumulative incidence rates of local failure for all targets were 4.6%, 8.4%, and 19%, respectively. The presence of epidural disease (subdistribution hazard ratio [sHR] 5.43, p = 0.04) and SSRS as reirradiation (sHR 16.5, p = 0.02) emerged as significant predictors of local failure in a multivariate model. Hormone sensitivity did not predict local control. Vertebral fracture incidence rates leading to symptoms or requiring intervention at 1, 2, and 4 years were 1.1%, 3.7%, and 8.4%, respectively. In an exploratory analysis of patterns of failure, 3 (25%) failures occurred in the epidural space and only 1 (8%) occurred clearly in the clinical tumor volume. There were several lesions for which the precise location of failure with regard to target volumes was unclear.

CONCLUSIONS
High rates of local control were observed, particularly for radiotherapy-naïve lesions without epidural disease. Hormone sensitivity was not predictive of local control in this cohort and fracture risk was low. Further research is needed to better predict which patients are at high risk of recurrence and who might benefit from treatment escalation.
Fueling the future of neurosurgery: increasing trends in female enrollment expanding the neurosurgical workforce from 2010 to 2019
Authors: Smith Eleanor C. , Calafiore Rebecca L. , Oravec Chesney S. , Kittel Carol , Wolfe Stacey Q. , White Jaclyn J. 
Published: June 2024

OBJECTIVE
Regular reporting on recruitment of women into neurosurgery is a mechanism to track the progress of minority inclusion and diversity. For more than 20 years, half of US medical students have been women, yet a disproportionate minority pursue a career in neurosurgery. The authors previously published data tracking women in neurosurgery for the prior decade from 2000 to 2009, which showed an increasing match rate of women over time, from 18 women matched at the beginning of the decade to 36 matched at the end. They now present updated data on the matriculation of women into neurosurgical residencies across the most recent decade, from 2010 to 2019.

METHODS
Public databases from the Association of American Medical Colleges were analyzed for applicants to neurosurgical residency from 2010 to 2019. Demographic data for those matched was obtained from the American Medical Association Masterfile and analyzed for year of match and gender. Secondary outcomes included program location, age, and gap year(s) between medical school and residency.

RESULTS
Women made up 18.8% (394/2094) of residents matched into neurosurgery from 2010 to 2019, compared to 12% during the previous decade. There was an increase in overall match rate of 2.2% per year (male + female) from 2010 to 2019, representing the predicted need for expansion of the neurosurgical workforce to meet national needs. Women made up the majority of this expansion, rising by 5.5% over the time period (p = 0.002), compared to men increasing by 1.4% over the time period (p = 0.096). The percentage of women applicants who matched was 34.4%, compared to men at 38.6% (p = 0.009). There was no significant difference in gender with regard to age, number of gap years, or program location.

CONCLUSIONS
The number of women matching into neurosurgery has continued to increase across the last 2 decades. Despite this, there remains significant disparity between the number of men and women matching into neurosurgery. Ongoing mitigation of barriers to recruitment of women into neurosurgery is critical. The authors’ data highlight the fact that women are important to fueling the expansion of the neurosurgical workforce.
The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis
Authors: Alper David P. , Almeida Mariana N. , Hu Kevin G. , Yang Jenny F. , Timberlake Andrew T. , Shah Jinesh , Persing John A. , Alperovich Michael 
Published: June 2024

OBJECTIVE
Previous work identified an association between genetics and neurodevelopmental delays in patients with nonsyndromic craniosynostosis. The authors investigated the role of genetic mutations on behavioral outcomes of patients with treated sagittal synostosis.

METHODS
Parents of children aged 6–18 years with surgically corrected sagittal synostosis were recruited to complete the Child Behavioral Checklist (overall behavioral problems), Conners 3rd Edition–Parent (attention-deficit/hyperactivity disorder), Social Responsiveness Scale 2nd Edition (autism spectrum disorder [ASD]), and Behavior Rating Inventory of Executive Function 2nd Edition (executive function). Genomic analysis was completed, and patients were identified if they had mutations in high probability of loss of function intolerant (pLI) genes (high pLI vs nonhigh pLI). Genetic burden was assessed relative to controls. Multivariate linear regression determined the association of mutations in high pLI genes with behavioral scores, while controlling for sociodemographic factors, age at surgery, surgery type, and IQ.

RESULTS
Sixteen of 45 patients were in the high pLI group. There were no differences between the groups in terms of sociodemographic factors. A greater proportion of children in the high pLI group scored at or above borderline clinical levels for aggression (18.8% vs 0.0%, p = 0.05) and externalizing problems (31.3% vs 3.7%, p = 0.02). Among children in the nonhigh pLI group, older age at surgery was associated with worse scores on the rule-breaking, aggression, and externalizing problems domains and four out of five ASD domains.

CONCLUSIONS
Children with treated nonsyndromic sagittal synostosis and mutations in high pLI genes had worse behavioral problems in externalizing behaviors and aggression, whereas older age at surgery was a significant predictor of worse behavioral outcomes in patients without mutations in high pLI genes.
Focal selective dorsal rhizotomy and concurrent deformity correction: a combined approach
Authors: Gadgil Nisha , Schwabe Aloysia L. , Wright Edward , Barbuto Amy , Dugan Eric L. , Thomas Sruthi P. , Shilt Jeffrey S. , Beauvais Dorothy , Shih Yushane , Smith Brian G. , Bauer David F. , Curry Daniel J. 
Published: June 2024

OBJECTIVE
Selective dorsal rhizotomy (SDR) is a neurosurgical procedure to reduce spasticity in children with cerebral palsy and spastic diplegia. The authors developed a procedure called focal SDR for children with spasticity predominantly in the L5 or S1 motor distribution, which can be combined with orthopedic correction of fixed soft-tissue or bony deformity. The authors describe in detail the technique of minimally invasive focal SDR and propose selection criteria.

METHODS
The authors conducted a retrospective study of patients who underwent focal SDR at their institution and underwent baseline and 1-year postoperative 3D gait analysis. Modified Ashworth scale (MAS) and Gait Deviation Index (GDI) scores were the primary outcome measures.

RESULTS
Ten patients met the study criteria, all with an underlying diagnosis of cerebral palsy. All underwent focal SDR at the unilateral or bilateral S1 level, and 4 additionally underwent focal SDR at the L5 level unilaterally or bilaterally. All but 1 patient underwent concurrent orthopedic surgery. The improvement in spasticity of the plantar flexors, as measured by the MAS score, was 2.2 (p < 0.001). In the patients who underwent L5 focal SDR, there was an improvement in the hamstring MAS score of 1.4 (p = 0.004). The mean improvement in the GDI score following focal SDR was 11 (range −6 to 29, p < 0.001).

CONCLUSIONS
Focally impairing spasticity in the gastrocsoleus complex and/or hamstrings muscle group in the setting of less functionally impactful proximal tone is extremely common in cerebral palsy. The novel technique of focal SDR, combined with orthopedic intervention, improves spasticity scores and overall gait mechanics. Further investigation is warranted to define the ideal candidacy and outcomes.
Walka Hieronima z herezjami chrystologicznymi w świetle nauczania o Chrystusie zawartym w jego Listach
Authors: Łukaszczyk Michał 
Published: June 2024

Artykuł opisuje herezje chrystologiczne występujące w Listach św. Hieronima. Są to arianizm, apolinaryzm, herezje, które głoszą ebionici i nazaretanie, herezje wyznające doketyzm oraz pelagianizm. Autor Wulgaty w opisywanych herezjach wykazuje nie tylko na błędy doktrynalne, ale również broni w swoich pismach ortodoksji wiary chrześcijańskiej. Artykuł wskazuje ponadto na istotne zagadnienia w chrystologii, na które zwrócił uwagę Mnich z Betlejem. Chodzi głównie o pomieszanie pojęć w grece i łacinie dotyczących terminów οὐσία i ὐπόστασις (spiritus asper), próba przywrócenia im właściwego znaczenia, formowanie właściwego znaczenia i rozumienia pojęcia persona, wskazywanie na niebezpieczeństwa pelagianizmu oraz powiązanie go z wcześniejszymi herezjami w celu zwrócenia uwagi na jego zgubne działanie.
PENGARUH KEPERCAYAAN DAN SOCIAL COMMERCE CONSTRUCT PADA MINAT BELI KONSUMEN DI JAWA BARAT
Authors: Triyana S Desna Archelia , Sucherly Sucherly , Oesman Yevis Marty 
Published: June 2024

Penelitian ini bertujuan untuk mengetahui pengaruh kepercayaan dan social commerce construct pada minat beli konsumen di jawa barat. Variabel Independen dalam penelitian ini yaitu kepercayaan dan social commerce construct , sementara variabel dependen pada penelitian ini yaitu minat beli konsumen. Responden dalam penelitian ini adalah pengguna situs social commerce yang pernah mmembeli produk maupun layanan jasa secara online. Penelitian ini menggunakan metode kuantitatif dengan teknik survei melalui kuesioner dan analisis Smart PLS. Sampel dalam penelitian ini berjumlah 210 pelanggan. Hasil penelitian menunjukkan bahwa terdapat pengaruh kepercayaan terhadap minat beli konsumen melalui social commerce construct, terdapat pengaruh kepercayaan terhadap minat beli konsumen, terdapat pengaruh social commerce construct terhadap minat beli konsumen dan terdapat pengaruh kepercayaan terhadap social commerce construct.
Conversational Analysis of Adjacency Pairs in “The Murder of Roger Ackroyd” Novel by Agathe Christie
Authors: Al-Sa’adoon Hadeel , Al-Zubaidy Baidaa 
Published: June 2024

تُعنى هذه الدراسة في الدور المحوري للأزواج المتجاورة كوحدات اساسية في تحليل المحادثة , مع التركيز بشكل خاص على تطبيقها في سياق الروايات البوليسية والتي تتجسد بشكل ملحوظ في اعمال أجاثا كرستي . تعتبر الأزواج المتجاورة , والتي تتكون من جزء الزوج الأول و جزء الزوج الثاني اداة حاسمة في فهم دينامكيات الحوار لأنها تكشف عن الهياكل والمعاني الأساسية داخل المحادثات . وبالتالي تهدف الدراسة الحالية الى تحديد النمط الأكثر شيوعاً بين الازواج المتجاورة والتي استخدمت في تشكيل الحوار في اعمال كرستي, والتحقيق في كيفية توظيف كرستي لنمط زوج مجاور محدد لأضفاء لمسة مميزة على رواياتها البوليسية .
وفي ضوء ما ذُكر أعلاه من أهداف عامة ، فقد طرحت هذه الدراسة عدداً من الفرضيات للبحث في مصداقيتها : أولاً , تصدُّر نمط ( سؤال – جواب/ توضيح ) جميع الأنماط الأخرى. ثانياً, توظيف نمط ( اعلان – قبول / رفض) بطريقة غير متوقعة للتعرف على المجرم في الرواية. ولأختبار صحة هذه الفرضيات المذكورة آنفاً فقد تم تحليل رواية ( مقتل روجر اكرويد ) لأجاثا كرستي وذلك بأعتماد نماذج انتقائية وهم كولتهارد (1985) , كلارك (1996) , شيكلوف (2007) و بالتريدج (2012) . تم تحديد نتائج التحليل باتباع نهج الأساليب الكمية والنوعية . لتحقيق أهداف الدراسة والتحقق من فرضياتها , لا بد من اتباع بعض الأجراءات منها عرض جميع انواع الأزواج المتجاورة و مراجعة المصطلحات اللغوية ذات الصلة التي تتناول مفهوم الأزواج المتجاورة . . تستخلص هذه الدراسة الى انه يمكن للكُتّاب الأستفادة من استخدام أجاثا كرستي الماهر لتوظيف الأزواج المتجاورة ( سؤال – جواب لرفع تأثير الســـرد. كما يمكن لكُتّاب السيناريو الذين يقومون بتكييف اعمال أجاثا كرستي مع الوسائط المرئية الأستفادة من فهم أهمية هذه الأزواج في توجيه بناء الحوار للتصوير السينمائي. أيضاً يمكن دمج هذه الأفكار في دورات الأدب أو علم اللغة كدراسات حالة , لتكون بمثابة ادوات تعليمية لتوضيح الوسائل اللفوية الفعالة و تعميق فهم الأستراتيجيات السـردية.
A Critical Discourse Analysis Study of Reduplication in Some Selected English Newspapers Headlines
Authors: Farhan Mahmood 
Published: June 2024

ان تحليل الخطاب النقدي على العموم يكون موّجه تجاه تحليل الخطابات الاعلامية اضافة الى الخطابات السياسية. ان المشكلة الاساس في الدراسة الحالية تتركز على توظيف تحليل الخطاب النقدي في التحقق من الوسائل اللغوية لظاهرة التضعيف الصرفي في بعض عنوانات الصحف الانكليزية والهدف الاساس من هذه الدراسة هو تحليل العناصر اللغوية لهذه الظاهرة عن طريق تبني منهج فيركلف ذو الثلاث ابعاد (2001) وطرحت الدراسة الفرضيات التالية:

تضم اعلانات الصحف الانكليزية في طياتها الخواص النصية والخطابية والاجتماعية المختلفة
ان النموذج التحليلي هو أفضل نموذج مستخدم في هذه الدراسة

ومن اجل تحقيق اهداف هذه الدراسة والتحقق من الفرضيات تم استخدام منهج تحليل الخطاب النقدي هذه الدراسة والمتمثل بمنهج فيركلف الثقافي الاجتماعي
والدراسة الحالية تحرّت عن استخدام هذه الظاهرة في بعض عنوانات الصحف الامريكية والبريطانية التي تشمل صحيفة الكارديان والواشنطن بوست والتليكراف والاوبزرفر والفاينشال تايمز وتوّصلت الدراسة الى الاستنتاجات التالية:

ان عنوانات الصحف توصف على انها توّظف او تستخدم مفردات غير رسمية بسيطة
يتصف اسلوب الكتابة بالدقة والوضوح والمباشرة اذ ان محرري هذه الصحف يستخدمون كلمات مادية محددة وشائعة لإقناع القرّاء
يظهر التحليل الدلالي بان المفردات القاموسية تشمل التصاحب اللغوي والمرادفات والاستعارة وذلك لتعزيز لغة الاقناع فيما يظهر التحليل الصرفي بان محرري الصحف يستخدمون تضعيف صرفي مختلف وذلك لتحقيق الهدف المنشود الذي يسعى اليه المحررون اما التحليل الاجتماعي فيكشف لنا بان المحررين يجدون فترات ومناسبات واماكن وشخصيات سياسية مختلفة.
Penerapan Customer Relationship Management (CRM) Pada UMKM Merdeka Sumedang Binaan Coca-Cola Europacific Partners Indonesia
Authors: Fauziah Sabila Nurul , Novel Nurillah Jamil A. , Wahyudi Denny 
Published: June 2024

Perkembangan UMKM di Indonesia mencapai 66 juta ditahun 2023. Biasanya, setiap UMKM memiliki permasalahan yang serupa seperti pemasaran, permodalan, pengelolaan keuangan, legalitas usaha, dan distribusi. Kehadiran CCEP Indonesia sebagai bentuk tanggung jawab kepada lingkungan akan membantu UMKM melalui pembinaan. Salah satu daerah yang dibantu adalah Kabupaten Sumedang. Kelima UMKM Binaan CCEP Indonesia bagian Sumedang Plant memiliki permasalahan yang serupa dengan UMKM pada umumnya. Namun, salah satu yang menjadi perhatian berkaitan dengan penerapan customer relationship management (CRM), sehingga tujuan penelitian ini untuk menggambarkan penerapan dan analisis sederhana mengenai CRM di lima UMKM yang dibina CCEP Indonesia. Metode yang digunakan dalam penelitian ini adalah kualititatif dengan pendekatan deskriptif. Metode pengumpulan data yang dilakukan untuk penelitian ini adalah wawancara, observasi, dan studi pustaka. Berdasarkan analisis yang dilakukan, kelima UMKM menerapkan CRM secara sederhana dan penggunaan CRM dalam digitalisasi masih belum maksimal. Analisis ini dilakukan melalui pendekatan technology-based relationship, brand-based relationship, dan human-based relationship.
Pengaruh Budaya Organisasi, Workplace Friendship dan Etos Kerja terhadap Organizational Citizenship Behavior (OCB)
Authors: Anisa Mutiara , Khasanah Nur 
Published: June 2024

Penelitian ini bertujuan untuk menganalisis pengaruh Budaya organisasi, Workplace Friendship, dan Etos Kerja terhadap Organizational Citizenship Behavior (OCB) pada PNS Pengadilan Agama Kebumen. Pengumpulan data menggunakan kuisioner dengan skala Likert dan jumlah sampel sebanyak 36 responden. Teknik sampling yang digunakan dalam penelitian ini adalah sampling jenuh. Hipotesis diuji menggunakan teknik analisis regresi berganda, uji t, uji f dan koefisien determinasi dengan menggunakan SPSS for windows versi 23.00. Hasil penelitian ini menunjukan bahwa Budaya organisasi, secara parsial berpengaruh signifikan terhadap Organizational Citizenship Behavior (OCB), Workplace Friendship secara parsial berpengaruh signifikan terhadap terhadap Organizational Citizenship Behavior (OCB), Etos Kerja, secara parsial berpengaruh signifikan terhadap Organizational Citizenship Behavior (OCB). Budaya organisasi, Workplace Friendship, Dan Etos Kerja secara simultan berpengaruh terhadap Organizational Citizenship Behavior (OCB).