bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Efficient and General Synthesis of 3‐Aminoindolines and 3‐Aminoindoles via Copper‐Catalyzed Three‐Component Coupling Reaction.
Authors: Chernyak Dmitri , Chernyak Natalia , Gevorgyan Vladimir 
Published: August 2010

Abstract3‐Aminoindolines are prepared in a novel highly efficient and general copper‐catalyzed three component coupling reaction.
ChemInform Abstract: PdCl2‐Catalyzed Domino Reactions of 2‐Alkynylbenzaldehydes with Indoles: Synthesis of Fluorescent 5H‐Benzo[b]carbazol‐6‐yl Ketones.
Authors: Tang Ri‐Yuan , Li Jin‐Heng 
Published: August 2010

AbstractDepending on the reaction temperature, the title reaction affords either benzo‐fused carbazoles or isochromenylindoles.
ChemInform Abstract: Silica‐Bonded S‐Sulfonic Acid: A Recyclable Catalyst for the Synthesis of Trisubstituted Imidazoles under Solvent‐Free Conditions.
Authors: Niknam Khodabakhsh , Mohammadizadeh Mohammad R. , Mirzaee Salimeh , Saberi Dariush 
Published: August 2010

AbstractA silica‐bonded S‐sulfonic acid is shown to be an efficient catalyst for the synthesis of trisubstituted imidazoles, e.g. (III).
ChemInform Abstract: Tandem [8 + 2] Cycloaddition—[2 + 6 + 2] Dehydrogenation Reactions Involving Imidazo[1,2‐a]pyridines and Imidazo[1,2‐a]pyrimidines.
Authors: Aginagalde Maialen , Vara Yosu , Arrieta Ana , Zangi Ronen , Cebolla Vicente L. , Delgado‐Camon Arantzazu , Cossio Fernando P. 
Published: August 2010

AbstractThe resulting tetracyclic products exhibit interesting photophysical properties.
ChemInform Abstract: Biologic Activity of Benzimidazole Derivatives.
Authors: Zniber Rachid , Moussaif Ahmed , Achour Radouane , El Ghoul Mostafa , Filali Maltouf Abdelkrim , Mekkak Abdel Illah , Harrata Abdelkamel 
Published: August 2010

AbstractThe title compounds (VIII) show antibacterial activity against Gram‐positive bacteria whereas (V) also exhibits activity against Gram‐negative bacteria.
ChemInform Abstract: Highly Substituted 2,3‐Dihydroisoxazoles by Et3N‐Catalyzed Tandem Reaction of Electron‐Deficient 1,3‐Conjugated Enynes with Hydroxylamines.
Authors: Yu Xiuzhao , Du Bo , Wang Kai , Zhang Junliang 
Published: August 2010

AbstractA wide range of multifunctionalized 2,3‐dihydroisoxazoles is prepared, tolerating many functional groups as ketones, esters, aldehydes, aromatic and aliphatic substituents.
ChemInform Abstract: Copper(I)‐Zeolites as New Heterogeneous and Green Catalysts for Organic Synthesis.
Authors: Chassaing Stefan , Alix Aurelien , Boningari Thirupathi , Sido Karim Sani Souna , Keller Murielle , Kuhn Philippe , Louis Benoit , Sommer Jean , Pale Patrick 
Published: August 2010

AbstractCu(I)‐modified USY‐zeolite is used for the regioselective 1,3‐dipolar cycloaddition of azides, generated in situ, or the azomethine (VI) with terminal alkynes.
ChemInform Abstract: One‐Pot, Three‐Component Synthesis of 4‐Aryl‐5,6‐dihydropyran via Prins—Friedel—Crafts Reaction.
Authors: Reddy Udagandla C. , Saikia Anil K. 
Published: August 2010

AbstractBF3·OEt2 promotes the reaction of homopropargylic alcohol (I) with a variety of aldehydes and with epoxides in the presence of arenes to give the title compounds.
ChemInform Abstract: A Highly Effective One‐Pot Synthesis of Quinolines from 2‐Alkynylnitrobenzenes.
Authors: Okuma Kentaro , Ozaki Saori , Seto Jun‐ichi , Nagahora Noriyoshi , Shioji Kosei 
Published: August 2010

Abstract2‐Alkynylnitrobenzenes (I) are used as starting materials for the synthesis of arylketones of type (II), quinolines of type (IV) or acridine derivatives, e.g. (VI).
ChemInform Abstract: Intramolecular Cobalt‐Catalyzed [2 + 2 + 2] Cycloaddition of O‐Protected Diyne‐Cyanohydrins.
Authors: Meissner Anja , Groth Ulrich 
Published: August 2010

Abstract6‐Substituted octahydrophenanthridines (II) are readily available via the title process.
ChemInform Abstract: Synthesis and in vitro Cytotoxic Evaluation of Novel Pyridazin‐4‐one Derivatives.
Authors: Mojahidi Souad , Rakib El Mostapha , Sekkak Hanan , Abouricha Said , Benchat Nouredine , Mousse Hassan Ait , Zyad Abdelmajid 
Published: August 2010

AbstractNovel pyridazine derivatives are synthesized and tested for their cytotoxic activity on the P815 cell line.
ChemInform Abstract: Synthesis of 4‐Allylquinazolines from N‐(2‐Cyanoaryl)amides via the In‐Mediated Allylation of Nitrile and Dehydrative Cyclization Cascade.
Authors: Kim Sung Hwan , Kim Se Hee , Kim Taek Hyeon , Kim Jae Nyoung 
Published: August 2010

AbstractThe sequence yields 4‐allylquinazolines (III) and (V).
ChemInform Abstract: Convenient Selective Synthesis of 5,7,8,9‐Tetrahydro‐4H,6H‐chromeno[2,3‐d][1,3]oxazin‐4‐ones
Authors: Litvinov Yu. M. , Shestopalov A. M. 
Published: August 2010

Abstractvia acid‐catalyzed acylation of 2‐amino‐tetrahydrochromene‐3‐carboxylates (I)
ChemInform Abstract: Enantioselective Construction of Allylic Phosphine Oxides Through Substitution of Morita—Baylis—Hillman Carbonates with Phosphine Oxides.
Authors: Hong Liang , Sun Wangsheng , Liu Chunxia , Zhao Depeng , Wang Rui 
Published: August 2010

AbstractThe asymmetric organocatalytic allylic substitution reaction of MBH carbonates (I) with phosphines (II) is described.
ChemInform Abstract: A Ring Contraction Strategy Toward a Diastereoselective Total Synthesis of (+)‐Bakkenolide A (VII).
Authors: Carneiro Vania M. T. , Ferraz Helena M. C. , Vieira Tiago O. , Ishikawa Eloisa E. , Silva Luiz F. Jr. 
Published: August 2010

AbstractThe key steps are a ring contraction of the octalone (I) and stereoselective formation of the keto ester (VI).
ChemInform Abstract: Thiadiazole‐Based Thioglycosides as Sodium‐Glucose Co‐Transporter 2 (SGLT2) Inhibitors.
Authors: Gao Yunlong , Zhao Guilong , Liu Wei , Wang Yuli , Xu Weiren , Wang Jianwu 
Published: August 2010

AbstractA series of 16 thiadiazole‐based thioglycosides of type (IV) or (VI) are prepared and tested in vivo as sodium‐glucose co‐transporter 2 (SGLT2) inhibitors.
ChemInform Abstract: First Total Synthesis of a Fluorinated Calystegin.
Authors: Csuk Rene , Prell Erik , Reissmann Stefan , Korb Claudia 
Published: August 2010

AbstractA straightforward chiral pool synthesis of 3‐fluorocalystegin B2 analogue (VIII) is described involving an ultrasound‐assisted Zn‐mediated ring opening reaction [→(V)] followed by a ring closing metathesis as the key steps.
ChemInform Abstract: Nosokomycins, New Antibiotics Discovered in an in vivo‐Mimic Infection Model Using Silkworm Larvae. Part 1. Fermentation, Isolation and Biological Properties.
Authors: Uchida Ryuji , Iwatsuki Masato , Kim Yong‐Pil , Ohte Satoshi , Omura Satoshi , Tomoda Hiroshi 
Published: August 2010

AbstractThe four new antibiotics nosokomycins A‐D (Ia)‐(Id), resp., are isolated from a culture broth of Streptomyces sp.
Nanoscale Metal–Organic Frameworks: MRI Contrast Agents and Beyond Metals@MOFs – Loading MOFs with Metal Nanoparticles for Hybrid Functions Construction of Three‐Dimensional Uranyl–Organic Frameworks with Benzenetricarboxylate Ligands Silica–MOF Composites as a Stationary Phase in Liquid Chromatography (Eur. J. Inorg. Chem. 24/2010)
Authors: Lin Wenbin , Fischer Roland A. , Chen J.‐S. , De Vos Dirk E. 
Published: August 2010

AbstractThe cover picture a schematic design of a porous metal–organic framework as the background. Embedded in the MOF are illustrations representing some of the thought‐provoking contributions that make up this Cluster Issue entitled “Targeted Fabrication of MOFs for Hybrid Functionality”. With a focus towards application, this issue serves to showcase the research at the forefront of the field. The top left‐hand graphic symbolises the use of nanoscale MOFs as MRI contrast agents (W. Lin et al.; p. 3725 ff), while the bottom left depicts the use of MOFs as supports for metal nanoparticles in catalysis (R. A. Fischer et al.; p. 3701 ff). The structure–property relationship of uranyl–organic frameworks (top right‐hand corner), important in photovoltaics is highlighted by J.‐S. Chen et al. (p. 3780 ff), and the synthesis of MOF composites for use as a stationary phase in HPLC (bottom right‐hand corner) is discussed by D. E. De Vos et al. (p. 3735 ff). A sincere thanks to the authors for their excellent contributions to the cover. We thank Heulwen Price for designing the background.
Quantification of glycolipids in cereal and dairy matrices
Authors: Cotting Claudia , Giuffrida Francesca 
Published: August 2010

AbstractGlycolipids are currently divided into three main classes: glycerolipids, containing a glycerol backbone; glycosphingolipids, containing a sphingosin backbone; and polyisoprenoid glycolipids. Glycolipids are well known for their excellent emulsifier properties and health benefits. However, they represent a small fraction of lipid compounds and because of their amphiphilic nature, their precise quantification is not straightforward.
Nanowire‐Based Sensors
Authors: Ramgir Niranjan S. , Yang Yang , Zacharias Margit 
Published: August 2010

AbstractNanowires are important potential candidates for the realization of the next generation of sensors. They offer many advantages such as high surface‐to‐volume ratios, Debye lengths comparable to the target molecule, minimum power consumption, and they can be relatively easily incorporated into microelectronic devices. Accordingly, there has been an intensified search for novel nanowire materials and corresponding platforms for realizing single‐molecule detection with superior sensing performance. In this work, progress made towards the use of nanowires for achieving better sensing performance is critically reviewed. In particular, various nanowires types (metallic, semiconducting, and insulating) and their employment either as a sensor material or as a template material are discussed. Major obstacles and future steps towards the ultimate nanosensors based on nanowires are addressed.
Concurrent Precipitation of AlN and VN in Microalloyed Steel
Authors: Radis R. , Kozeschnik E. 
Published: August 2010

AbstractThe precipitation kinetics of AlN and VN in microalloyed steel is investigated numerically with the thermo‐kinetic software MatCalc. To mimic the heterogeneous precipitation of AlN along austenite grain boundaries, a new model is utilized, which takes into account the fast short circuit diffusion along grain boundaries and sluggish bulk diffusion inside the grains. It is demonstrated that the precipitation of VN inside the grains can be more rapid than the precipitation of AlN at the grain boundaries. However, the thermodynamically more stable AlN can overgrow and dissolve the existing VN again. The computed results are compared to experimental results from literature and good agreement is observed.
On the Formation of Centreline Segregation in Continuous Slab Casting of Steel due to Bulging and/or Feeding
Authors: Mayer F. , Wu M. , Ludwig A. 
Published: August 2010

AbstractCentreline macrosegregation is often observed in continuous slab casting of steel. Two of the main macrosegregation formation mechanisms are bulging and feeding. Both were studied and compared in the current work by using a two‐phase volume averaging model considering only columnar solidification. The casting of the strand itself is modelled by applying a predefined velocity following the casting speed and solid shell deformation (e.g. bulging). Three different cases are simulated and discussed. (i) The first case considers the influence of the feeding flow during solidification without taking bulging into account. Negative macrosegregation is observed in the centre of the casting in this case. (ii) The second case takes the flow caused by series of bulging along the solidifying strand shell into account, and is, therefore, representative for an ideal situation where bulging takes place without solidification shrinkage. In this case positive centreline segregation is found. (iii) The last case shows the results of a simulation which combines both shrinkage‐ and bulging‐induced flows. It is found that under the current casting conditions the bulging effect dominates over the shrinkage effect, and so positive centreline segregation is predicted.
Synoptic analysis of a rare event of Saharan dust reaching the Arctic region
Authors: Barkan Joseph , Alpert Pinhas 
Published: August 2010

AbstractA rare event of Saharan dust cloud in the subarctic region north of the Scandinavian Peninsula was discovered by the LiDAR of the Arctic LiDAR Observatory (ALOMAR) on 7 August. The origin of this cloud was from the permanent dust reservoir which exists in the atmosphere above the Sahara and was not necessarily a result of a single dust storm. The wind flow and the geopotential height at 700mbar in the area bounded by 0°N–80°N and 100°W–40°E were examined for 1–4 August. Additionally, the 6–7 day forward trajectories from the location 28°N–0°E were computed for the same time. It was found, that during 1–2 August, a strong southwesterly flow formed in northern Africa and western Europe, between a trough along the Atlantic coast of southern Europe and northern Africa and the eastern branch of the subtropical high. This synoptic situation was suitable to long‐range transportation of the dust from the Sahara to the Arctic. © 2010 Royal Meteorological Society
A short meteorological overview of the Eyjafjallajökull eruption 14 April–23 May 2010
Authors: Petersen Guðrún Nína 
Published: August 2010

AbstractOn 14 April 2010 a subglacial explosive eruption started Eyjafjallajökull, situated on the southcentral coast of Iceland. This was a medium‐size eruption but due to the explosive nature and the prevailing winds during that first week, the ash was advected southeastward into the crowded air space of the UK and continental Europe. This caused major disruptions of air traffic. Volcanic eruptions are not uncommon in Iceland but the Eyjafjallajökull eruption has shown different characteristics than usually expected. Instead of peaking during the first few days and then gradually decreasing, the eruption had an explosive phase 14–17 April with mainly tephra and ash production, and a phase of mainly lava production 18–30 April before becoming explosive again. This meant that a continuous reevaluation of the strength of the eruption and the production of tephra and ash was necessary. Because the winds carried the ash a short distance overland, only a small part of Iceland, about 3%, was badly affected by ash fall. However, the rural community in the vicinity of the volcano that experienced the worst ash fall is also facing problems with drifting ash. The purpose of the article is to give a short overview of the eruption, in a meteorological sense, during the period 14 April–23 May 2010. Copyright © 2010 Royal Meteorological Society
Explaining why this body gives rise to me qua subject instead of someone else: an argument for classical substance dualism
Authors: HIMMA KENNETH EINAR 
Published: August 2010

AbstractSince something cannot be conscious without being a conscious subject, a complete physicalist explanation of consciousness must resolve an issue first raised by Thomas Nagel, namely to explain why a particular mass of atoms that comprises my body gives rise to me as conscious subject, rather than someone else. In this essay, I describe a thought-experiment that suggests that physicalism lacks the resources to address Nagel's question and seems to pose a counter-example to any form of non-reductive physicalism relying on the mind–body supervenience thesis, which would include William Hasker's emergent dualism. Since the particular thought-experiment does not pose any problems for classical substance dualism (CSD) and since the problem, as I call it, of explaining subjectivity is the central problem of mind, I conclude that CSD is better supported than any form of non-reductive physicalism.
Sentence-Position Effects on Children’s Perception and Production of English Third Person Singular–s
Authors: Sundara Megha , Demuth Katherine , Kuhl Patricia K. 
Published: August 2010

PurposeTwo-year-olds produce third person singular –smore accurately on verbs in sentence-final position as compared with verbs in sentence-medial position. This study was designed to determine whether these sentence-position effects can be explained by perceptual factors.MethodFor this purpose, the authors compared 22- and 27-month-olds' perception and elicited production of third person singular –sin sentence-medial versus-final position. The authors assessed perception by measuring looking/listening times to a 1-screen display of a cartoon paired with a grammatical versus an ungrammatical sentence (e.g.,Sheeatsnowvs.Sheeatnow).ResultsChildren at both ages demonstrated sensitivity to the presence/absence of this inflectional morpheme in sentence-final, but not sentence-medial, position. Children were also more accurate at producing third person singular –ssentence finally, and production accuracy was predicted by vocabulary measures as well as by performance on the perception task.ConclusionsThese results indicate that children’s more accurate production of third person singular–sin sentence-final position cannot be explained by articulatory factors alone but that perceptual factors play an important role in accounting for early patterns of production. The findings also indicate that perception and production of inflectional morphemes may be more closely related than previously thought.
Cytotoxicity of commercial and novel binary titanium alloys with and without a surface‐reaction layer
Authors: Watanabe I. , Wataha J. C. , Lockwood P. E. , Shimizu H. , Cai Z. , Okabe T. 
Published: August 2010

summary Titanium‐based alloys form a surface reaction layer when cast. This study investigated the effect of the surface reaction layer on the cytotoxicity of novel Ti‐based binary alloys. The cytotoxicities of the novel alloys were compared with commercially pure titanium, Ti‐6Al‐4V and Ti‐6Al‐7Nb. Cast discs with or without the reaction layer were first tested for cytotoxicity, then for elemental release into cell‐culture medium. The elements released into the extracts were measured by means of an inductively coupled plasma atomic emission spectrometer. The commercial and novel binary Ti‐based alloys showed no statistically significant cytotoxicity, although some trends were noted for several alloys. The presence of the reaction layer did not significantly alter the cytotoxicity. These favourable biocompatibility results show that these novel alloys have promise for use in dental restorations.
Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing
Authors: Cho Minseon , Xiao Yi , Nie Jeff , Stewart Ron , Csordas Andrew T. , Oh Seung Soo , Thomson James A. , Soh H. Tom 
Published: August 2010

We describe the integration of microfluidic selection with high-throughput DNA sequencing technology for rapid and efficient discovery of nucleic acid aptamers. The Quantitative Selection of Aptamers through Sequencing method tracks the copy number and enrichment-fold of more than 10 million individual sequences through multiple selection rounds, enabling the identification of high-affinity aptamers without the need for the pool to fully converge to a small number of sequences. Importantly, this method allows the discrimination of sequences that arise from experimental biases rather than true high-affinity target binding. As a demonstration, we have identified aptamers that specifically bind to PDGF-BB protein with
K

d

< 3 nM within 3 rounds. Furthermore, we show that the aptamers identified by Quantitative Selection of Aptamers through Sequencing have ∼3–8-fold higher affinity and ∼2–4-fold higher specificity relative to those discovered through conventional cloning methods. Given that many biocombinatorial libraries are encoded with nucleic acids, we extrapolate that our method may be extended to other types of libraries for a range of molecular functions.
Russian Manufacturing Industry in the Mirror of its Exports to the European Union
Authors: Soos Karoly Attila , Ivleva Ekaterina , Levina Irina 
Published: August 2010

The purpose of this study is to shed some light on structural changes in the manufacturing industry of Russia and eight other transition countries during the last decade. The export performance of countries in one and the same market can under certain conditions be used to compare the state of the art in national industries. On the basis of full and comparable trade data from Eurostat, we perform comparative analysis of the development of manufacturing exports to the European Union by Russia and eight other transition countries over the period 1993–2000. The transition countries selected for comparison are Hungary, the Czech Republic, Poland, Romania, Bulgaria, Estonia, Latvia, and Ukraine. For all these countries, as well as for Russia, the European Union is the most important trade partner.The paper provides a comparative analysis of the breakdown of manufacturing exports by factor intensities, export concentration and specialisation, and relative price positions in the European market. All these approaches give a rather unfavourable picture of Russia’s performance. We observe a relative shrinking in exports of labour–intensive, specialised–supplier and science–based sectors. At the same time the role of the sector based on natural resources, which was traditionally predominant in Russia’s exports, is strengthening further. We also observe an alarmingly high level of concentration in Russia’s manufacturing exports and their growing specialisation in base metals, together with an intense de–specialisation in engineering products.
DOUBLE BLIND TRIAL OF LONG‐TERM ANTICOAGULANT TREATMENT AFTER MYOCARDIAL INFARCTION
Authors: Meuwissen O. J. A. T. , Vervoorn A. C. , Cohen O. , Jordan F. L. J. , Nelemans F. A. 
Published: August 2010

Abstract A prospective double blind trial of long‐term anticoagulant medication following myocardial infarction was carried out in Utrecht from May 1, 1964 to January 15, 1966. With the collaboration of all Utrecht cardiologists, all their patients with acute myocardial infarction were included in this trial after a 4‐month interval, to be distributed strictly at random over a phenprocoumon and a placebo group. Supplemental therapy and follow‐up were identical in both groups. Of the total of 138 patients included in the trial, 68 received phenprocoumon and 70 were given a placebo. One patient died in the phenprocoumon group, and eight patients died in the placebo group. This difference is significant (P < 0.01). The difference in the number of reinfarctions was not significant (5 cases and 7 cases, respectively).After January 15, 1966, when the difference between the two groups had become significant, all patients were further treated with phenprocoumon. Nevertheless, the difference in mortality continued through 1966, with five deaths in the original placebo group and only one death in the original phenprocoumon group.The mean thrombotest level was 10.7%; patients remained within the therapeutic limits (5–15% thrombotest) during an average of 91% of the entire period of investigation. The mean daily phenprocoumon dose was 3.21 mg. No serious haemorrhagic complications occurred.The results of our study are consistent with those of several other recently published investigations. The intensity of the hypocoagulability attained is probably of decisive importance in this respect. However, correct calculation of the mean level of hypocoagulability is difficult.The fact that in the original placebo group the results remained less favourable even after the switch to phenprocoumon emphasizes the necessity of long‐term treatment with adequate doses of anticoagulants following myocardial infarction.