bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of alanine aminotransferase/aspartate aminotransferase ratio and high-density lipoprotein for predicting neonatal adverse outcomes associated with intrahepatic cholestasis of pregnancy
Authors: Fan Xizhenzi , Li Xia , Yu Tianxiao , Jiao Ruifen , Song Wenhui , Su Achou , Li Mingwei , Guo Qing 
Published: June 2024

Background
To determine the association between lipid metabolism and intrahepatic cholestasis of pregnancy (ICP), and explore the value of maternal alanine aminotransferase/aspartate aminotransferase (ALT/AST) and high-density lipoprotein (HDL) in predicting adverse neonatal outcomes in women with ICP.

Methods
A total of 147 pregnant women with ICP admitted to The Fourth Hospital of Shijiazhuang and 120 normal pregnant women in the same period were selected in this study. The Mann-Whitney U test and Chi-square tests were used to compare the differences in clinical data. Multivariate logistic regression was used to analyze the relationship between ALT/AST and the occurrence of adverse pregnancy outcomes in patients with ICP. The combined predictive value of ALT/AST and HDL was determined by receiver operating characteristic (ROC) curve analysis.

Results
Among 147 women with ICP, 122 women had total bile acid (TBA) levels of 10–39.9 µmol/L, and 25 had TBA ≥ 40 µmol/L. There was significantly lower gestational age in patients with severe ICP than in those with mild and control groups (all p < 0.05), and the weight of newborns in the maternal ICP group was significantly lower than in the control group (p < 0.05). Increasing TBA levels was associated with higher AST, ALT, ALT/AST, and lower HDL level (all p < 0.05). Meanwhile, higher levels of ALT/AST was positively associated with neonatal hyperbilirubinemia [adjusted odds ratio (AOR) = 4.019, 95% CI [1.757–9.194, p = 0.001] and cardiac injury [AOR = 3.500, 95% CI [1.535–7.987], p = 0.003]. HDL was a significant protective factor for neonatal hyperbilirubinemia and cardiac injury [AOR = 0.315, 95% CI [0.126–0.788], p = 0.014; AOR = 0.134 (0.039–0.461), p = 0.001]. The area under the ROC curve (AUC) for prediction of neonatal hyperbilirubinemia by ALT/AST combined with HDL was 0.668 [95% CI [56.3–77.3%], p = 0.002], and the sensitivity and specificity were 47.1% and 84.0%, respectively. To predict neonatal cardiac injury, the AUC value was 0.668 [95% CI [56.4–77.1%], p = 0.002], with sensitivity and specificity were 41.2% and 87.1%, respectively.

Conclusions
The levels of higher ALT/AST and lower HDL were significantly associated with the risk of ICP-related adverse neonatal outcomes. Moreover, ALT/AST combined with HDL has moderate clinical value in predicting the adverse outcomes of neonatal hyperbilirubinemia and cardiac injury.
Microbial Contamination and Nutritional Evaluation of Poultry Feeds in Abidjan District Farms
Authors: Djoman Christelle Suzanne , Akpa Eric Essoh , Goualié Bernadette Gblossi , Djeneba Ouattara Hadja , Samagassi Lamine , N’Guessan Delphine Yevi 
Published: June 2024

This study aims to evaluate the biochemical and microbial quality of poultry feeds in farms of the Abidjan district. Thus, 164 samples of industrial feeds and farmer-formulated feeds were collected in Bingerville, Yopougon, Port-Bouet, Anyama and Songon areas for microbiological and biochemical analysis. The microbiological analysis consisted of isolation and identification of bacterial and fongical flora potentially pathogenic for the animal. The biochemical analysis was aimed to evaluate the nutritional composition of these feeds. Results showed that among these samples, 15 (10.33%), 91 (55.48%) and 48 (29.26%) were positive respectively for Salmonella sp., E. coli and Aspergillus sp. Moreover, biochemical analysis showed low feeds moisture rate levels ranging from 7.52 ± 0.16% to 12.14 ± 0.05%. Feeds formulated by farmers had low content in ash, protein and lipid with proportions ranging from 4.30 ± 0.15% to 11.61 ± 0.24%, 9.30 ± 0.24% to 15.81 ± 0.20% and 2.07 ± 0.02% to 3.68 ± 0.11% respectively when compared to commercial feeds.
In conclusion, the study shows a poor hygienic quality of the feeds used in modern poultry husbandry in the Abidjan district. However, the content of analyzed feeds content are mostly in conformity with the recommended standards.
Positive Outcome in a Pregnancy with Anti-kell Alloimmunization Treated with Intravenous Immunglobulin and Therapeutic Plasma Exchange Despite Persistence of High Titre Antibody: A Case Report
Authors: Vio Cinzia , Colpo Anna , Collodel Luca , Marson Piero , Gessoni Gianluca 
Published: June 2024

Background: Few reports have been published about the current clinical management of anti-Kell alloimmunization in pregnancy; its low frequency of occurrence means that the few long series published have covered an extensive time period in which different treatment approaches have overlapped. The objective of the present paper is to present our experience in the clinical management of a pregnant woman who was positive for the anti-Kell antibody.
Materials and Methods: The laboratory follow-up included the weekly measurement of the antibody titre, and identification of the paternal and fetal genotype. The clinical management included TPE and IVIG administration. Obstetric monitoring included ultrasonographic monitoring of the fetus.
Case Description: We report a case of anti-Kell alloimmunization with high antibody titre at first observation. Testing for fetal DNA circulating in maternal blood confirmed positivity for KEL1 gene. The patient underwent fifteen sessions of TPE after 18 weeks of gestational age, followed by weekly IVIG infusion, which continued until 27 weeks of pregnancy. Anti-Kell titres were measured before and after each TPE session.
The patient had no need for IUBT and delivered by cesarean section at 34 weeks of gestational age. Pregnancy resulted in a live birth with mild HDFN.
Discussion: HDFN is a potentially lethal complication of alloimmunization, and IUBT is the standard treatment for severe fetal anemia. TPE and IVIG are two alternative treatment modalities described in the literature to avoid or postpone the need for IUBT transfusion. In the case reported, despite any substantial change in antibody titre, pregnancy resulted in a live birth. This result suggests that the use of TPE and IVIG in alloimmunization during pregnancy could be an effective treatment strategy.
Action as a Window to Perception: Measuring Attention with Mouse Movements
Authors: Johnson Addie , Mulder Ben , Sijbinga Ankie , Hulsebos Lucas 
Published: August 2012

SummaryEye‐gaze tracking has been shown to deliver valuable information about how people view advertisements and what they pay attention to. However, practical difficulties in its application limit its usability by marketing researchers. Here, we explore the use of mouse tracking to evaluate viewing behavior by determining whether the hand can be trained to follow visual spatial attention and whether visual processing can be estimated by tracking pointing movements made with a computer mouse. In brief, the results of the research are very promising, showing high correlations between the scan paths for the eye and the mouse, as well as high correlations between the percentage of time spent in designated regions of interest for the mouse and the eye. An additional comparison of the data with that of a group who did not use a mouse while viewing the experimental stimuli showed that viewing patterns were not disrupted by mouse use. Copyright © 2012 John Wiley & Sons, Ltd.
A globally convergent wind speed estimator for wind turbine systems
Authors: Ortega Romeo , Mancilla‐David Fernando , Jaramillo Fernando 
Published: August 2012

SUMMARYAn estimator of the wind speed of a wind turbine coupled to a generator is proposed in this paper. Wind speed enters into the generator dynamics through a highly nonlinear function; hence, we are confronted with a difficult problem of estimation of a nonlinearly parameterized system. To solve this problem, we use the technique of immersion and invariance, recently introduced in the literature. It is assumed that the rotor speed and electrical torque of the generator are measured, which is the case for the machines typically used in this application. The result is of interest for the design of controllers of maximum power extraction, where the knowledge of the wind speed is necessary to express the control objective as a speed tracking problem. Detailed computer simulations are presented to assess the performance of the proposed estimator.Copyright © 2012 John Wiley & Sons, Ltd.
Metal Nanoparticles Acting as Light‐Activated Heating Elements within Composite Materials
Authors: Maity Somsubhra , Bochinski Jason R. , Clarke Laura I. 
Published: August 2012

AbstractThe photothermal effect of metal nanoparticles embedded in polymeric materials can be used to efficiently generate local heat for in situ thermally processing within an existing material. Fluorescent probes are employed as thermal sensors to allow dynamical measurement of the amplitude and rate of temperature change within the polymer matrix. The efficacy of this technique is demonstrated in polymer nanocomposite samples with different morphological characteristics, namely nanofibrous mats and thin film samples. For similarly thick materials and both types of sample morphology, average temperature increases on the order of ≈100s °C are readily obtained with dilute nanoparticle concentrations under relatively low irradiation intensity. Thus, the in situ photothermal heating approach has great potential for controllably driving a multitude of thermal processes, such as triggering phase transitions, generating site‐specific cross‐linking, or initiating chemical reactions from within a material.
Hemorheological alterations, decreased cerebral microvascular oxygenation and cerebral vasomotion compensation in sickle cell patients
Authors: Waltz Xavier , Pichon Aurélien , Mougenel Danièle , Lemonne Nathalie , Lalanne‐Mistrih Marie‐Laure , Sinnapah Stéphane , Tarer Vanessa , Tressières Benoit , Lamarre Yann , Etienne‐Julan Maryse , Hue Olivier , Hardy‐Dessources Marie‐Dominique , Connes Philippe 
Published: August 2012

AbstractSickle cell anemia (SS) is characterized by a reduced cerebral microvascular oxygen saturation (cerebral TOI), which is not associated with hemoglobin concentration. Cerebral TOI has never been studied in sickle cell‐hemoglobin C disease (SC). We focused on the relationships between hemorheological alterations and cerebral TOI in sickle cell patients with no cerebral vasculopathy and on the usefulness of TOI variability to assess the cerebral vasomotion activity. The blood rheological profile, the level of cerebral TOI (spatial resolved spectroscopy) and the cerebral TOI variability, which reflects vasomotion activity, were compared between 20 healthy subjects (AA), 21 SC patients, and 21 SS patients. Cerebral TOI exhibited the following order: AA > SC > SS. The low cerebral TOI in SS patients was related to red blood cell aggregation and deformability properties. The cerebral TOI variability of SS and SC patients was increased above healthy values and vasomotion activity was negatively associated with the reduced cerebral TOI in SS patients. We demonstrated that (1) blood rheology could be involved in the reduced cerebral TOI in SS patients but not in SC patients; (2) vasomotion activity is increased in SS and SC patients to compensate for the reduced cerebral TOI. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
Acute GVHD is a strong predictor of full donor CD3+ T cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation
Authors: El‐Cheikh Jean , Vazquez Alberto , Crocchiolo Roberto , Furst Sabine , Calmels Boris , Castagna Luca , Lemarie Claude , Granata Angela , Ladaique Patrick , Oudin Claire , Faucher Catherine , Chabannon Christian , Blaise Didier 
Published: August 2012

AbstractThe monitoring of chimerism is a standard procedure to assess engraftment and achievement of full donor lymphoid cells after reduced intensity conditioning (RIC) stem cell transplantation (Allo‐SCT). However, there is no consensus on when and how often to monitor post‐transplant chimerism. We retrospectively analyzed our experience regarding the impact of acute graft versus host disease (GVHD) for the prediction of allograft chimerism. One‐hundred‐and‐fifteen patients transplanted between 2001 and 2010 were identified. This group included 57 females and 58 males with a median age of 50 years (range: 26–68). Patients evaluated in this study were adult patients with hematologic malignancies, who received transplants from an HLA‐matched sibling donor or matched unrelated donor (MUD) at allele level so‐called 10/10, and received the RIC regimen including fludarabine/busulfan and anti‐thymoglobulin (ATG). Mixed T‐cell chimerism was defined as between 5 and 94% recipient cells, and full chimerism was defined as the presence of more than 95% donor T‐cell chimerism (TCC). Full donor TCC was achieved in 93 patients (81%) at a median of 77 days (range: 30–120) post‐transplant. The cumulative incidence of Grade 2–4 GVHD in our population was 25% (95% CI 17–34). The analysis of the population of patients with acute GVHD grade ≥2 showed that at day 120 after Allo‐SCT they all had a total full donor TCC. On the other hand, 78 (68%) patients without acute GVHD grade ≥2 presented with mixed chimerism (p = 0.002) on day 120 post‐transplant. Interestingly, patients who received ATG 5 mg/kg obtained a higher probability of complete chimerism compared with those receiving 2.5 mg/kg (p = 0.03). In conclusion, our study demonstrates that acute GVHD was predictive of full donor TCC after RIC Allo‐SCT. Therefore, our data may challenge the concept of the frequent or close monitoring of donor chimerism in some patients with ongoing acute GVHD. However, chimerism testing could represent an attractive modality for minimal residual disease detection or for impeding relapse warranting further prospective studies. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
Preparation and swelling behaviors of porous hemicellulose‐g‐polyacrylamide hydrogels
Authors: Sun Xiao‐Feng , Jing Zhanxin , Wang Guangzheng 
Published: August 2012

AbstractNovel porous hydrogels were successfully synthesized from hemicelluloses (HCs) and acrylamide (Am) with poly(ethylene glycol) (PEG) as the porogen. The prepared hydrogels were characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, and scanning electron microscopy (SEM). The results show that the used PEG was not involved in the formation process of the hydrogels, and the HC‐g‐polyacrylamide hydrogels displayed a higher thermal stability than the hemicellulosic polymer. SEM analysis confirmed that the prepared hydrogels had porous structures. The effects of the Am/HC ratio, the amount and molecular weight of PEG and the amount of the crosslinker N,N‐methylene bisacrylamide on the swelling ratio of the prepared hydrogels were investigated in detail. The experimental data were fitted with the exponential heuristic equation and the Schott second‐order dynamic equation. The diffusion of water molecules into the hydrogel network was found to be non‐Fickian in behavior, and the swelling kinetics could be described by the Schott second‐order dynamic equation. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Effects of periodic and non‐periodic chaotic mixing on morphology development of immiscible polymer blends
Authors: Wang Jia‐Jun , Yang Yi‐Wei , Gu Xue‐Ping , Feng Lian‐Fang 
Published: August 2012

AbstractThe effects of periodic and non‐periodic chaotic mixing on the morphology development in the blending of polypropylene as dispersed phase and polyamide 6 as continuous phase in a 2D batch chaotic mixer were investigated with experimental and computational fluid dynamic (CFD) methods. The rotor motions were delivered in steady, periodic (sine waveform and square waveform), and non‐periodic (recursive protocol (RP) and restricted random sequence (RRS)) manners. The mixing efficiency was evaluated with flow number, Poincare map, morphology, droplet size and its distribution. Compared with the sine waveform, RP waveform could eliminate the island structures which existed in the flow domains and its corresponding spatial stretching distribution was more uniform. The recursively generated flow using RP lead to higher mixing efficiency and smaller droplet size with narrow distribution. However, the performance of RRS was ordinary even worse due to its random sequence.© 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
A massive spoonbill stopover episode: identifying emergency sites for the conservation of migratory waterbird populations
Authors: Overdijk O. , Navedo J. G. 
Published: August 2012

ABSTRACT

The existence of emergency sites could reduce the mortality rate associated with stochastic adverse weather conditions experienced by migratory waterbirds. However, as they are not regularly used by significant fractions of any population they are not integrated within conservation strategies.
A massive stopover of Eurasian spoonbill (Platalea leucorodia) occurred simultaneously at three coastal wetlands in northern Spain (Txingudi, Urdaibai and Santoña) during 3 consecutive days in September 2011. By analysing the resightings of PVC‐ringed birds it was estimated that it comprised 18% of the population. At least 23% of these birds made short journeys between sites, the majority (77%) overwintering in Africa. A higher percentage of spoonbills that stopped over at Txingudi overwinter in Africa compared with the other areas.
During September 2011 there were more periods of consecutive days with adverse wind conditions than any other year. Furthermore, wind conditions during the massive stopover, as well as precipitation, exerted a continuous negative influence on the resumption of migration, lasting 3 consecutive days.
The scarcity of consecutive days with favourable winds and adverse weather conditions further encountered once en route probably led to an emergency strategy developed by a significant fraction of a spoonbill population, with several birds choosing then to make a short diversion in a westerly direction from Txingudi. Since this stopover site usually appears to be skipped during migration, it will not fit Ramsar Criterion 6 for spoonbills even after including the massive stopover (c. 7%), because average numbers will hardly satisfy the requisite of ‘regularly supporting’ a population.
A criterion is proposed to identify emergency sites for the conservation of migratory waterbird populations thus improving landscape connectivity and accounting better for long‐term natural variability associated with stochastic adverse events. Being a flagship and umbrella species, the recognition of emergency sites for spoonbills would help the conservation of other associated waterbirds. Copyright © 2012 John Wiley & Sons, Ltd.
Non‐Redox‐Metal‐Catalyzed Redox Reactions: Zinc Catalysts
Authors: Wu Xiao‐Feng 
Published: August 2012

AbstractThe advantages of zinc catalysts, such as their low toxicity, low cost, and environmentally benignity, are encouraging organic chemists to explore their applications in organic synthesis. As a non‐redox metal, zinc catalysts have been investigated in redox reactions over the past few decades. Because of the importance of redox reactions, the interest in zinc catalysts, and the fact that no review on zinc‐catalyzed redox reactions has been published, herein, I have collected and summarized the main contributions in this area. This review is divided into two parts: reduction reactions and oxidation reactions.
A comparison of three Met Office wind observing systems
Authors: Sloan C. , Clark M. R. 
Published: August 2012

AbstractResults of a side‐by‐side comparison of wind speed, as measured by three Met Office observing systems, are presented. Mean wind speeds as measured by each system differed by < 1.0 knots (0.5 m s−1) at wind speeds of up to 30 knots (15.4 m s−1). Although differences increased slightly with increasing wind speed, they remained within user‐specified accuracy limits over the whole range of wind speeds experienced. The trial set‐up involved the mounting of anemometers on a single mast. Although a slight sheltering of anemometers occurred at given wind directions, the effect on the overall wind speed differences was negligible. © 2012 British Crown copyright, the Met Office. Published by John Wiley & Sons Ltd.
Hygroscopic growth and cloud activation of pollen: a laboratory and modelling study
Authors: Griffiths P. T. , Borlace J.‐S. , Gallimore P. J. , Kalberer M. , Herzog M. , Pope F. D. 
Published: August 2012

AbstractThis study investigates the hygroscopic growth of pollen. An electrodynamic balance was used to measure the water uptake on pollen and an environmental scanning electron microscope was used to visualize the response of the pollen to subsaturated humidities. Pollen was found to be moderately hygroscopic and its surface wettable at high humidities. The hygroscopicity data were parameterized using κ‐Köhler theory and used in a rising parcel cloud model to investigate the effect of pollen on sulfate activation. Our data suggest that extreme pollen concentrations (>1000 m−3) may interfere with the activation of the background sulphate aerosol mode in pristine environments. Copyright © 2012 Royal Meteorological Society
The role of soil moisture–atmosphere coupling in summer light precipitation variability over East Asia
Authors: Wu Lingyun , Zhang Jingyong , Huang Gang 
Published: August 2012

AbstractThis study investigates the role of soil moisture feedbacks in influencing interannual variability of summer light precipitation frequency over East Asia by analyzing two long‐term simulations with and without interactive soil moisture using the Weather Research and Forecasting model coupled with the Noah land model. It is shown that soil moisture–atmosphere coupling significantly amplifies interannual variability of summer light precipitation frequency over many areas, in particular the climatic and ecological transition zones, contributing to 30–60% of the variance. The results suggest that soil moisture‐atmosphere coupling constitutes an important cause explaining the variations of summer light precipitation events over East Asia. Copyright © 2012 Royal Meteorological Society
Alte Obstsorten erhalten: das Boomgarden‐Projekt
Authors: Högermann Christiane 
Published: August 2012

AbstractVor dem Hintergrund, dass alte norddeutsche Apfelsorten in den vergangenen Jahrzehnten zunehmend aus dem Sortenrepertoire verschwunden sind, hat der Obstbauer Eckart Brandt ein Projekt zu ihrem Erhalt ins Leben gerufen. Dabei stehen die mit dem vielfältigen genetischen Material verbundene Biodiversität, natürliche Resistenzen gegen Schädlinge sowie geschmackliche Besonderheiten im Vordergrund.