bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: B‐Chlorodialkylboranes for the Enolboration of 3,3,3‐Trifluoropropionates.
Authors: Ramachandran P. Veeraraghavan , Gagare Pravin D. , Parthasarathy Gowrisankar 
Published: February 2012

AbstractOptimized conditions are elaborated and boron reagent NBC is found to be the most efficient one to give diastereomerically pure products (III) from ester (I).
ChemInform Abstract: Metal‐Free Synthesis of Amides by Oxidative Amidation of Aldehydes with Amines in PEG/Oxidant System.
Authors: Liang Jun , Lv Jing , Shang Zhi‐cai 
Published: February 2012

AbstractA green, simple, inexpensive, and efficient one‐pot synthesis of amides using a PEG/oxidant system is reported.
ChemInform Abstract: Aromatics from Pyrones: para‐Substituted Alkyl Benzoates from Alkenes, Coumalic Acid and Methyl Coumalate.
Authors: Kraus George A. , Riley Sean , Cordes Travis 
Published: February 2012

AbstractThe Diels—Alder reaction of title coumalic acid derivatives with unactivated alkenes provides exclusively para‐substituted adducts in good yields.
ChemInform Abstract: Direct Asymmetric α‐Benzoyloxylation of Cyclic Ketones.
Authors: Lifchits Olga , Demoulin Nicolas , List Benjamin 
Published: February 2012

AbstractThe asymmetric benzoyloxylation of cyclic ketones with dibenzoyl peroxide is efficiently catalyzed by chiral cinchona alkaloid‐derived primary amines and BHT to give the corresponding α‐benzoyloxy ketones, e.g. (III) or (IX), in good yields with high enantioselectivities (up to 96% e.e.).
ChemInform Abstract: Enantioselective Carbon—Sulfur Bond Formation: γ‐Additions of Aryl Thiols to Allenoates Catalyzed by a Chiral Phosphepine.
Authors: Fujiwara Yuji , Sun Jianwei , Fu Gregory C. 
Published: February 2012

AbstractAn axially chiral phosphepine efficiently catalyzes the asymmetric addition of arylthiols to the γ‐position of allenoates.
ChemInform Abstract: Ruthenium‐Catalyzed Arylation of Fluorinated Aromatic Ketones via ortho‐Selective Carbon—Fluorine Bond Cleavage.
Authors: Kawamoto Keisuke , Kochi Takuya , Sato Mitsuo , Mizushima Eiichiro , Kakiuchi Fumitoshi 
Published: February 2012

AbstractSubstrates (I) and (IV) are phenylated by dioxaborinane (II) under optimized conditions A).
ChemInform Abstract: Calcium Carbide as a Cost‐Effective Starting Material for Symmetrical Diarylethynes via Pd‐Catalyzed Coupling Reaction.
Authors: Chuentragool Padon , Vongnam Kunnigar , Rashatasakhon Paitoon , Sukwattanasinitt Mongkol , Wacharasindhu Sumrit 
Published: February 2012

AbstractThe coupling reaction of aryl iodides with calcium carbide tolerates a wide range of functional groups.
ChemInform Abstract: A Robust Pure Hydrocarbon Derivative Based on the (2,1‐b)‐Indenofluorenyl Core with High Triplet Energy Level
Authors: Poriel Cyril , Metivier Remi , Rault‐Berthelot Joelle , Thirion Damien , Barriere Frederic , Jeannin Olivier 
Published: February 2012

Abstractdesign, synthesis and characterization of title compound (X)
ChemInform Abstract: One‐Pot Synthesis of Functionalized Spirobenzofuranones via MCR Involving 3‐Cyanochromones.
Authors: Zarganes‐Tzitzikas Tryfon , Terzidis Michael A. , Stephanidou‐Stephanatou Julia , Tsoleridis Constantinos A. , Kostakis George E. 
Published: February 2012

AbstractTreatment of 3‐cyanochromones with isocyanides and acetylenecarboxylates allows a new and facile access to spirobenzofuranones of biological interest.
ChemInform Abstract: Synthesis and Photophysical Properties of Novel 4‐Aryl Substituted Thiophene Derivatives.
Authors: Xu Zhaozhe , Yu Mingxin 
Published: February 2012

AbstractA series of novel fluorescent aryl‐substituted thiophene derivatives (V) is obtained via palladium‐catalyzed cross‐coupling reaction of various aryl boronic acids with (Z)‐3(4‐bromothiophen‐2‐yl)‐2‐phenylacrylonitrile (III).
ChemInform Abstract: Concise Synthesis of 3‐Acetoxy‐N,N‐dialkylbenzo[b]thiophene‐2‐carboxamides from 2‐Ethylsulfanylbenzoates.
Authors: Kobayashi Kazuhiro , Kanbe Yuuki , Horiuchi Mai 
Published: February 2012

AbstractIt is demonstrated that otherwise difficult to prepare 3‐acetoxythiophenes of type (VI) can be easily synthesized in three steps from 2‐ethylsulfanyl benzoates using an interrupted Pummerer reaction of substrates (IV) as the key step.
ChemInform Abstract: Palladium‐Catalyzed Direct Monoarylation of Thiophene‐, Benzothiophene‐, and Indoleacetic Acids Through Regioselective C—H Bond Cleavage.
Authors: Takeda Daisuke , Yamashita Mana , Hirano Koji , Satoh Tetsuya , Miura Masahiro 
Published: February 2012

AbstractThe title reaction leads to arylation at the C‐2 position yielding products of pharmaceutical interest.
ChemInform Abstract: Regioselective Synthesis of Multisubstituted Pyrazoles via Cyclocondensation of β‐Thioalkyl‐α,β‐unsaturated Ketones with Hydrazines.
Authors: Jin Weiwei , Yu Haifeng , Yu Zhengkun 
Published: February 2012

AbstractThe title reaction offers a regioselective synthesis of highly functionalized pyrazole structures.
ChemInform Abstract: Four‐Component Reaction Between Trimethyl Phosphite, Aroyl Chlorides and Dialkyl Acetylenedicarboxylate with Benzoic Acid Hydrazide
Authors: Hassanabadi Alireza , Mosslemin Mohammad H. , Anary‐Abbasinejad Mohammad , Ghazvininejad Farzaneh , Koocheki Somayeh 
Published: February 2012

Abstractas a simple and efficient route for the synthesis of functionalized pyrazoledicarboxylates (IV) (8 examples)
ChemInform Abstract: One‐Pot Synthesis of 5‐Sulfonamidopyrazole from Terminal Alkynes, Sulfonyl Azides and Hydrazones.
Authors: Li Yao , Hong Deng , Zhu Yuanxun , Lu Ping , Wang Yanguang 
Published: February 2012

AbstractTitle synthesis involves a copper‐catalyzed three‐component reaction and a Lewis acid‐catalyzed electrocyclization—dehydrogenation.
ChemInform Abstract: Copper‐Catalyzed N‐Arylation of Imidazoles with Aryl or Heteroaryl Halides Facilitated by Dimethylglyoxime in Water.
Authors: Wu Xiangmei , Hu Weiya 
Published: February 2012

AbstractThe reaction is conducted under environmentally benign conditions and works also with aryl iodides as starting material.
ChemInform Abstract: One‐Pot Synthesis of Benzothiazol‐2‐amines by Cyclization of the Adducts Between 2‐Iodophenyl Isothiocyanates and Amines under Metal‐Free Conditions.
Authors: Kobayashi Kazuhiro , Kobayashi Akihiro , Murahashi Kazuya , Fukamachi Shuhei 
Published: February 2012

AbstractA mild and catalyst‐free one‐pot method for the synthesis of benzothiazol‐2‐amines and their corresponding dimers is presented.
ChemInform Abstract: Synthesis and Antibacterial Activity of Some Novel N2‐Hydroxymethyl and N2‐Aminomethyl Derivatives of 4‐Aryl‐5‐(3‐chlorophenyl)‐2,4‐dihydro‐3H‐1,2,4‐triazole‐3‐thione.
Authors: Plech Tomasz , Wujec Monika , Kapron Barbara , Kosikowska Urszula , Malm Anna 
Published: February 2012

AbstractTitle compounds (I) and (II), prepared by methods according to reported protocols, are screened for their antibacterial activity against six Gram‐positive and four Gram‐negative bacterial strains.
ChemInform Abstract: Synthesis and in vitro Anticancer Activity of 3,5‐Bis(indolyl)‐1,2,4‐thiadiazoles.
Authors: Kumar Dalip , Kumar N. Maruthi , Chang Kuei‐Hua , Gupta Ritika , Shah Kavita 
Published: February 2012

AbstractA novel protocol using iodosylbenzene diacetate is applied to the oxidative cyclization of indolyl substituted thioxamides.
ChemInform Abstract: Synthesis and Antiinflammatory Activity of Some New 4,5‐Dihydro‐1,5‐diaryl‐1H‐pyrazole‐3‐substituted‐heteroazole Derivatives.
Authors: Dekhane Deepak V. , Pawar Shivaji S. , Gupta Sunil , Shingare Murlidhar S. , Patil C. R. , Thore Shivaji N. 
Published: February 2012

AbstractOxadiazoles (Ia), (Ib) and tetrazole derivatives (II) exhibit significant antiinflammatory activity.
ChemInform Abstract: Synthesis and Biological Evaluation of α,β‐Unsaturated Lactones as Potent Immunosuppressive Agents.
Authors: Lee Sun‐Mi , Lee Won‐Gil , Kim Young‐Chul , Ko Hyojin 
Published: February 2012

AbstractThe immunosuppressive efficacy of title compounds, e.g. (II), is studied by using an ELISA method to quantify the IL‐2 inhibition.
ChemInform Abstract: N‐Heterocyclic Carbene (NHC) Catalyzed Annulation of Enals and Vinyl Ketones: A Novel Synthesis of [2H]‐Pyranones.
Authors: Nair Vijay , Paul Rony Rajan , Lakshmi K. C. Seetha , Menon Rajeev S. , Jose Anu , Sinu C. R. 
Published: February 2012

AbstractThe homoenolate annulation to vinyl ketones gives dihydropyranone derivatives in contrast to cyclopentenes resulting from homoenolate reaction of chalcones.
ChemInform Abstract: Regioselective Carbon—Carbon Bond Formation in the Reaction of 2‐Hydroxy‐2‐(trifluoromethyl)‐2H‐chromenes with Indoles Promoted by Lewis Acid.
Authors: Pang Wan , Han Jian Wei , Zhao Jing Wei , Zhu Shi Zheng 
Published: February 2012

AbstractThe regioselectivity depends on the electronic effect of the substituent on the indole.
ChemInform Abstract: Nanocrystalline Magnesium Oxide Stabilized Gold Nanoparticles: An Advanced Nanotechnology Based Recyclable Heterogeneous Catalyst Platform for the One‐Pot Synthesis of Propargylamines
Authors: Layek Keya , Chakravarti Rajashree , Kantam M. Lakshmi , Maheswaran H. , Vinu Ajayan 
Published: February 2012

Abstractvia three‐component coupling of aldehydes with amines and an alkyne
ChemInform Abstract: Expedient Synthesis of 3‐Substituted‐1,2,3,6‐tetrahydropyridines.
Authors: Alcaraz Lilian , Coquebert de Neuville Bertrand , Lister Andrew , Roberts Bryan 
Published: February 2012

AbstractTreatment of aryl or alkyl halides with Landsbury′s reagent (generated from pyridine and LiAlH4) results in an alkylation—reduction sequence which affords the title compounds as suitable intermediates or products of pharmaceutical interest.
ChemInform Abstract: Diastereoselective Arylation of Enantiopure 3‐Bromopiperidin‐2‐one Derived from (R)‐(‐)‐2‐Phenylglycinol with Organocuprate Reagents.
Authors: Romero Oscar , Castro Alejandro , Teran Joel L. , Gnecco Dino , Orea Maria L. , Mendoza Angel , Flores Marcos , Roa Luis F. , Juarez Jorge R. 
Published: February 2012

AbstractThe 3‐bromolactam (I) derived from (R)‐2‐phenylglycinol undergoes a stereoselective reaction with arylcuprate reagents.
ChemInform Abstract: PPA—SiO2 Catalyzed Efficient Synthesis of Polyhydroquinoline Derivatives Through Hantzsch Multicomponent Condensation under Solvent‐Free Conditions.
Authors: Khojastehnezhad Amir , Moeinpour Farid , Davoodnia Abolghasem 
Published: February 2012

AbstractThe synthesis is advantageous with regards to short reaction times, simple experimental and work‐up procedures.
ChemInform Abstract: Ruthenium‐Catalyzed Intramolecular Carbocyclization of Alkynes with an sp3 Carbon Involving an Oxidative Deprotonation Process.
Authors: Tang Bo‐Xiao , Song Ren‐Jie , Wu Cui‐Yan , Wang Zhi‐Qiang , Liu Yu , Huang Xiao‐Cheng , Xie Ye‐Xiang , Li Jin‐Heng 
Published: February 2012

AbstractRuthenium‐catalyzed intramolecular cyclization of an alkyne onto an α‐amido C(sp3) carbon atom proceeds smoothly under base‐free conditions to give quinolinones (II) and (IV) in moderate yields.
ChemInform Abstract: Synthesis of 4‐Quinolones via Cyclocondensation of Substituted ortho‐Amidoacetophenones: A Refit to the Camps Cyclization by Applying Trimethylsilyl Trifluoromethanesulfonate/Triethylamine.
Authors: Eidamshaus Christian , Triemer Therese , Reissig Hans‐Ulrich 
Published: February 2012

AbstractTreatment of the substrates according to A) allows the selective preparation of various 2‐alkyl‐ or 2‐arylsubstituted quinolones.
ChemInform Abstract: Ytterbium Pentafluorobenzoate as a Novel Fluorous Lewis Acid Catalyst in the Synthesis of 2,4‐Disubstituted Quinolines.
Authors: Tang Jun , Wang Limin , Mao Dan , Wang Wenbo , Zhang Liang , Wu Shengying , Xie Yongshu 
Published: February 2012

AbstractA series of air‐stable and water‐tolerated rare earth metal pentafluorobenzoates are prepared for the first time.
ChemInform Abstract: Iron‐Catalyzed Oxidative Coupling of Alkylamines with Arenes, Nitroalkanes, and 1,3‐Dicarbonyl Compounds.
Authors: Shirakawa Eiji , Yoneda Tomoki , Moriya Kohei , Ota Kensuke , Uchiyama Nanase , Nishikawa Ryo , Hayashi Tamio 
Published: February 2012

AbstractThe presented catalytic oxidative system is also applicable to benzene derivatives, e.g. compound (VI).
ChemInform Abstract: Dehydrogenative Coupling Reactions Catalyzed by Rose Bengal Using Visible Light Irradiation.
Authors: Pan Yuanhang , Kee Choon Wee , Chen Li , Tan Choon‐Hong 
Published: February 2012

AbstractRose Bengal is shown to be a useful photoredox catalyst for dehydrogenative coupling reactions and Mannich reactions using visible light irradiation.
ChemInform Abstract: Synthesis of Novel Triplet Drugs with 1,3,5‐Trioxazatriquinane Skeletons and Their Pharmacologies. Part 2. Synthesis of Novel Triplet Drugs with the Epoxymethano Structure (Capped Homotriplet).
Authors: Nagase Hiroshi , Koyano Koji , Wada Naohisa , Hirayama Shigeto , Watanabe Akio , Nemoto Toru , Nakajima Mayumi , Nakao Kaoru , Mochizuki Hidenori , Fujii Hideaki 
Published: February 2012

AbstractAn improved synthetic method for oxazoline dimers using TosMIC is reported.
ChemInform Abstract: Palladium‐Catalyzed Highly Regioselective C‐3 Arylation of Imidazo[1,5‐a]pyridine.
Authors: Huang Chunhui , Giokaris Alexandros , Gevorgyan Vladimir 
Published: February 2012

AbstractWith respect to the aryl and hetaryl bromide a rapid and general method for the synthesis of the compounds (III) and (V) is presented.
ChemInform Abstract: Friedlaender Synthesis of Benzo[h]naphthyridines from o‐Aminoaldehydes.
Authors: Rote Ramhari V. , Shelar Deepak P. , Patil Sandeep R. , Jachak Madhukar N. 
Published: February 2012

AbstractThe synthetic utility of 4‐aminoquinoline‐3‐carbaldehyde (I) for the synthesis of a variety of benzonaphthyridine derivatives via Friedlaender condensation reactions with reactive methylene compounds or cyclic ketones under acidic, basic and neutral conditions is demonstrated.
ChemInform Abstract: Divergent Reactions of Indoles with Aminobenzaldehydes: Indole Ring‐Opening vs. Annulation and Facile Synthesis of Neocryptolepine.
Authors: Vecchione Matthew K. , Sun Aaron X. , Seidel Daniel , et al. et al. 
Published: February 2012

AbstractAcid‐promoted reaction of indoles (II) with secondary o‐aminobenzaldehydes (I) proceeds via an annulation pathway to give tetracyclic neocryptolepine derivatives (III).
ChemInform Abstract: Design, Synthesis and Structure—Activity Relationship of Novel [3.3.1] Bicyclic Sulfonamide‐Pyrazoles as Potent γ‐Secretase Inhibitors.
Authors: Aubele Danielle L. , et al. et al. 
Published: February 2012

AbstractThe SAR of a novel, potent and metabolically stable series of [3.3.1] bicyclic sulfonamide‐pyrazoles like (XI) which attenuate β‐amyloid peptide synthesis via γ‐secretase inhibition is reported.
ChemInform Abstract: Facile Synthesis of 8‐Azido‐6‐benzylaminopurine.
Authors: Steklov Mikhail Yu. , Tararov Vitali I. , Romanov Georgy A. , Mikhailov Sergey N. 
Published: February 2012

AbstractCompound (III) and the corresponding 2‐azido isomer, synthesized to prove the structure of (III), show typical cytokinin activity in model plant systems.
ChemInform Abstract: Imidazo[1,5‐a]quinoxalines as Irreversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.
Authors: Kim Kyung‐Hee , et al. et al. 
Published: February 2012

AbstractThe synthesis and SAR of a series of imidazo[1,5‐a]quinoxalines are described.
ChemInform Abstract: An Efficient One‐Pot Synthesis of Pyrimido[2,1‐b][1,3]thiazine Derivatives by Reaction of Activated Acetylenes, Thiouracils, and Isocyanides.
Authors: Baharfar Robabeh , Baghbanian Seyed Meysam , Vahdat Seyed Mohammad 
Published: February 2012

AbstractThe addition of isocyanides to dialkyl acetylenendicarboxylates generates zwitterionic intermediates which are intercepted by thiouracils to give pyrimidothiazines of type (IV)/(V).
ChemInform Abstract: Simultaneous Synthesis of 4,5‐Dihydro‐3H‐azepines and 3H‐Azepines, Bearing Alkoxy and Alkylsulfanyl Substituents, Through Metalation of 2‐Aza‐1,3,5‐trienes by t‐BuOK.
Authors: Nedolya Nina A. , Tarasova Ol'ga A. , Volostnykh Ol'ga G. , Albanov Alexander I. , Trofimov Boris A. 
Published: February 2012

AbstractAlkoxy‐ and alkylsulfanyl‐substituted azepines and dihydroazepines are formed in two steps starting from alkoxyallenes (I).
ChemInform Abstract: Novel Trinitrogen‐Containing Triheterocycles via the Intramolecular Nitrile Oxide Cycloaddition Reaction.
Authors: Ferreira Andrew J. , Solano Danielle M. , Oakdale James S. , Kurth Mark J. 
Published: February 2012

AbstractThree different types of isoxazoline‐containing polycyclic heterocycles are prepared from the corresponding oxime precursors (syntheses described).
ChemInform Abstract: Pyrimido[4,5‐d]azepines as Potent and Selective 5‐HT2C Receptor Agonists: Design, Synthesis, and Evaluation of PF‐3246799 (I) as a Treatment for Urinary Incontinence.
Authors: Andrew Mark D. , et al. et al. 
Published: February 2012

AbstractThe title compounds are prepared from phenylacetamidines using a short 4‐step synthesis.
ChemInform Abstract: Stereoselective Synthesis of Isoxazolinobenzoxepanes via Intramolecular Nitrile Oxide Cycloaddition.
Authors: Ramachandiran K. , Karthikeyan K. , Nandhakumar T. , Muralidharan D. , Perumal P. T. 
Published: February 2012

AbstractOptimized conditions are developed to generate nitrile oxides from indole‐tethered nitroalkanes of type (III).
ChemInform Abstract: Ganodermycin, a Novel Inhibitor of CXCL10 Expression from Ganoderma applanatum.
Authors: Jung Mathias , Liermann Johannes C. , Opatz Till , Erkel Gerhard 
Published: February 2012

AbstractGanodermycin (I), a novel inhibitor of CXCL10 expression, is isolated from Ganoderma applanatum.
ChemInform Abstract: Absolute Configurations of (‐)‐Hirsutanol A and (‐)‐Hirsutanol C Produced by Gloeostereum incarnatum.
Authors: Asai Ryo , Mitsuhashi Shinya , Shigetomi Kengo , Miyamoto Toshizumi , Ubukata Makoto 
Published: February 2012

Abstract(‐)‐Hirsutanol A (I) and (‐)‐hirsutanol C (II) are isolated from Gloeostereum incarnatum and their absolute configuration is determined.
ChemInform Abstract: Novel 4‐Azasteroidal N‐Glycoside Analogues Bearing Sugar‐Like D Ring: Synthesis and Anticancer Activities.
Authors: Huang Li‐Hua , Wang Yan‐Guang , Xu Gong , Zhang Xiang‐Hua , Zheng Yong‐Fei , He Hui‐Li , Fu Wen‐Zheng , Liu Hong‐Min 
Published: February 2012

AbstractOf the five title compounds presented, all members with purinyl moieties exhibit anticancer activity against breast cancer (MCF‐7), human neuroblastoma (SK‐N‐SH), cervical cancer cells (HeLa), and prostatic cancer (PC‐3).
ChemInform Abstract: Metal‐Free Direct Amidation of Peptidyl Thiol Esters with α‐Amino Acid Esters.
Authors: Chen Hao , He Maomao , Wang Yaya , Zhai Linhui , Cui Yongbo , Li Yangyan , Li Yan , Zhou Haibing , Hong Xuechuan , Deng Zixin 
Published: February 2012

AbstractA protocol for the direct amidation of peptidyl thiol esters promoted by bis(trimethylsilyl)acetamide is presented.
ChemInform Abstract: Synthesis of a Chiral β‐Amino Acid Derivative by a Cobalt‐Catalyzed Coupling Reaction.
Authors: Pan Xianhua , Yu Wansheng , Ou Wenhua , Tao Xiaohu , Wan Jiaomei , Liu Feng 
Published: February 2012

AbstractA novel synthetic route for the preparation of enantiopure amino acid derivative (III), a key intermediate in the synthesis of the dipeptidyl peptidase IV inhibitor sitagliptin, is reported.
ChemInform Abstract: A Cytotoxic Fellutamide Analogue from the Sponge‐Derived Fungus Aspergillus versicolor.
Authors: Lee Yoon Mi , Dang Hung The , Li Jianlin , Zhang Ping , Hong Jongki , Lee Chong‐O. , Jung Jee H. 
Published: February 2012

AbstractThe new lipopeptide, fellutamide F (I), shows strong cytotoxicity against a panel of five human solid tumor cell lines.
ChemInform Abstract: DABCO: An Efficient Promoter for the Acetylation of Carbohydrates and Other Substances under Solvent‐Free Conditions.
Authors: Ch Ratnasekhar , Tyagi Mohit , Patil Premanand Ramrao , Kartha K. P. Ravindranathan 
Published: February 2012

AbstractA convenient method is developed which can be applied to a broad spectrum of carbohydrates leaving functional and protecting groups unaffected.
ChemInform Abstract: Benzyl Glycosides from the Aerial Parts of Gynostemma laxum and Their NF‐ϰB Inhibitory Activity in HepG2 Cells
Authors: Ky Pham Thanh , Anh Pham Tuan , Kiem Phan Van , Minh Chau Van , Nhiem Nguyen Xuan , Tai Bui Huu , Ngan Nguyen Thi Thanh , Quang Tran Hong , Thao Nguyen Phuong , Kim Young Ho 
Published: February 2012

Abstractisolation, structural elucidation and evaluation of the inhibitory effects on NF‐ϰB activation, iNOS and COX‐2 expression of a new benzyl glycoside (I) along with nine known compounds
ChemInform Abstract: Synthesis of 1,6‐Anhydro Sugars Catalyzed by Silica Supported Perchloric Acid.
Authors: Chun Yuexing , Yan Shiqiang , Li Xiangpeng , Ding Ning , Zhang Wei , Wang Peng , Li Ming , Li Yingxia 
Published: February 2012

AbstractThe reaction requires only a few minutes under mild conditions.
ChemInform Abstract: Nucleosides. Part 7. Synthesis, Structure, and Biological Activity of New 6‐Arylidenamino‐2‐thio‐ and 2‐Benzylthiopyrimidine N‐Nucleosides.
Authors: Mosselhi Mosselhi A. N. , Break Laila M. 
Published: February 2012

AbstractThe glycosylation of azomethines such as (III) and (X) provides access to novel thiopyrimidine N‐nucleosides (VI), (VII), (XIII) and (XIV) which demonstrate moderate antibacterial and antifungal activities.
ChemInform Abstract: Dual Pro‐Drug of 2′‐C‐Methyl Guanosine Monophosphate as Potent and Selective Inhibitors of Hepatitis C Virus.
Authors: McGuigan Christopher , et al. et al. 
Published: February 2012

AbstractA previously reported potent anti‐HCV agent is modified in 6‐position of the purine moiety.
ChemInform Abstract: Biological Evaluation of Glycosyl‐isoindigo Derivatives Against the Pathogenic Agents of Tropical Diseases (Malaria, Chagas Disease, Leishmaniasis and Human African Trypanosomiasis).
Authors: Bouchikhi Fadoua , Anizon Fabrice , Brun Reto , Moreau Pascale 
Published: February 2012

AbstractNew indigoid derivatives bearing an acetylated sugar residue are synthesized and evaluated for their antiparasitic activity.
ChemInform Abstract: Antiviral Activity of Novel 2′‐Fluoro‐6′‐methylene‐carbocyclic Adenosine Against Wild‐Type and Drug‐Resistant Hepatitis B Virus Mutants.
Authors: Chu Chung K. , et al. et al. 
Published: February 2012

AbstractThe synthesis of the carbocyclic adenosine analogue (I), which demonstrates significant activity against wild‐type as well as drug‐resistant HBV‐mutants, is given.
ChemInform Abstract: Design and Synthesis of Biotinylated DHMEQ for Direct Identification of Its Target NF‐ϰB Components.
Authors: Saitoh Tsuyoshi , Takeiri Masatoshi , Gotoh Yuko , Ishikawa Yuichi , Umezawa Kazuo , Nishiyama Shigeru 
Published: February 2012

AbstractThe biotinylated dehydroxymethylepoxyquinomicin derivative (I) (one of two diastereomers shown) shows membrane permeability and combined selectivity with the target protein p65.
ChemInform Abstract: Design, Synthesis and Anticancer Activity of Novel Dihydrobenzofuro[4,5‐b][1,8]naphthyridin‐6‐one Derivatives.
Authors: Moon Hyung Ryong , et al. et al. 
Published: February 2012

AbstractRacemic title compounds (XII) and (XIII) are prepared as psorospermin analogues.
ChemInform Abstract: Identification of a Novel Cannabimimetic Phenylacetylindole, Cannabipiperidiethanone, as a Designer Drug in a Herbal Product and Its Affinity for Cannabinoid CB1 and CB2 Receptors.
Authors: Uchiyama Nahoko , Kikura‐Hanajiri Ruri , Goda Yukihiro 
Published: February 2012

AbstractThe new cannabimimetic phenylacetylindole (I) is found as an adulterant in herbal products illegally distributed in Japan.
ChemInform Abstract: Khatmiamycin, a Motility Inhibitor and Zoosporicide Against the Grapevine Downy Mildew Pathogen Plasmopara viticola from Streptomyces sp. ANK313.
Authors: Abdalla Muna Ali , Win Hnin Yu , Islam Md. Tofazzal , von Tiedemann Andreas , Schueffler Anja , Laatsch Hartmut 
Published: February 2012

AbstractThe new metabolite khatmiamycin (I) is isolated from the culture broth of a terrestrial Streptomyces sp.