bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amidoximated‐Wood Derived Carbons as Advanced Self‐Standing Electrodes for Supercapacitor and Water Splitting
Authors: Shen Liu‐Liu , Dong Xiangzun , Wang Wei , Yu Hui , Wu Peiran , Wang Jiansong , Xu Yipu , Cui Xuanxuan , Li Xinkun , Zhang Gui‐Rong , Mei Donghai 
Published: May 2024

AbstractWood‐derived carbons demonstrate great potential as self‐standing electrodes in energy storage/conversion applications, including supercapacitors and water‐splitting devices. However, the key challenge remains the rational customization of surface functionalities for optimized performance. This study introduces an innovative approach to self‐standing wood‐derived carbons with tailored nitrogen and metal functionalities. In contrast to traditional impregnation techniques, which offer limited precision in surface modification, this approach entails the intentional attachment of amidoxime groups to the wood substrates. These groups serve as nitrogen sources, and create abundant surface anchoring sites for metal ions due to the chelation between the amidoxime groups and metals. The resulting carbons feature uniform and high dispersion of nitrogen and metal functionalities, along with a distinctive hierarchical porosity combining interconnected open channels with abundant mesopores. As a proof‐of‐concept, different metals are incorporated (i.e., Mn, Co, Ni) into the amidoximated‐wood precursors, and the resulting self‐standing carbons showcase excellent performance in both supercapacitors and water‐splitting applications. Leveraging the specific chelating ability of amidoxime groups toward metal ions, this strategy holds great potential as a generic approach to systematically tailoring the surface functionalities of carbon‐based materials for various electrochemical energy storage/conversion processes.
Brain‐Targeted 9‐Phenanthrol‐Loaded Lipid Nanoparticle Prevents Brain Edema after Cerebral Ischemia‐Reperfusion Injury by Inhibiting the Trpm4 Channel in Mice
Authors: Liu Kewei , Peng Yuqin , Xu Mingheng , Yuan Kun , Li Yongchuan , Lin Chuman , Zhao Xiaolin , Zhu Juan , Chang Yuan , Lin Zhenzhou , Pan Suyue , Ma Huanrong , Wang Xiaorui , Huang Kaibin 
Published: May 2024

AbstractBrain edema robustly increases mortality and hinders functional recovery after acute ischemic stroke. However, there are currently no effective therapies available for treating or preventing it. The unchecked opening of the transient receptor potential M4 (TRPM4) channel results in an excessive influx of Na+ and water, which contributes significantly to the formation of brain edema after ischemic stroke. 9‐phenanthrol (9‐Phe), a potent TRPM4 inhibitor, has limited clinical applicability due to its potential cytotoxicity and poor solubility. A brain‐targeting T7 (HAIYPRH)‐modified lipid nanoparticle (LNP) encapsulated 9‐Phe (9‐Phe@T7‐LNP) is designed and synthesized to improve the physicochemical properties and pharmacokinetic properties of 9‐Phe for treating brain edema in vivo. These results demonstrated that 9‐Phe@T7‐LNP can penetrate the intact blood‐brain barrier (BBB) in normal mice and target the brain parenchyma. Moreover, 9‐Phe@T7‐LNP effectively reduced infarct volume and brain edema, prevented neuronal loss and BBB disruption, improved survival, and facilitated neurological function recovery after transient middle cerebral artery occlusion in mice. Additionally, 9‐Phe@T7‐LNP scavenged oxygen‐free radicals and prevented neuronal apoptosis in cultured neurons subjected to oxygen and glucose deprivation/reperfusion. In summary, these findings showed that 9‐Phe@T7‐LNP holds strong potential as a promising targeted therapy for brain edema after stroke, providing superior pharmacological neuroprotection against brain edema.
Dielectric Engineering of Perovskite BaMnO3 for the Rapid Heterogeneous Nucleation of Pt Nanoparticles for Catalytic Applications
Authors: Hughes Lucia , Roy Ahin , Yadav Neelam , Downing Clive , Browne Michelle P. , Vij Jagdish K. , Nicolosi Valeria 
Published: May 2024

AbstractMicrowave heating provides a rapid method for the heterogeneous nucleation of noble metal particles on perovskite support materials for electrocatalytic purposes. To succeed, dielectric tuning of perovskite materials becomes fundamental. Herein, the dielectric engineering of the BaMnO3 perovskite system is carried out through the use of B‐site doping to give BaTi0.5Mn0.5O3. Using a combination of atomic‐scale imaging and electron energy loss spectroscopy (EELS), the preferential filling of the M1 and M3 B‐sites with Mn and Ti ions in the 12R‐rhombohedral perovskite structure is established. While the addition of Ti in the BaMnO3 system has no detrimental effects on the presence of the oxygen reduction reaction (ORR) active Mn3+ states at the surface, it does alter the dielectric constant and loss tangent, thus facilitating the heterogeneous nucleation of Pt nanoparticles on BaTi0.5Mn0.5O3 via rapid microwave heating. Higher Pt loading regimes are found to increase the size and aggregation of the nucleated particles, thus reducing their ORR activity. Therefore, lower Pt loading not only reduces costs but improves overall activity. This work represents future possibilities for the dielectric engineering of perovskite and similar support materials to aid in the quick and easy formation of stable noble metal‐support catalytic systems.
Enhanced Thin‐Film Encapsulation Through Micron‐Scale Anchors
Authors: Mintz Hemed Nofar , Pham Albert , Zhao Eric T. , Wang Pingyu , Melosh Nicholas A. 
Published: May 2024

AbstractImplantable medical devices require protective encapsulation to isolate them from the biological environment. Parylene‐C (PaC) is a prevalent encapsulation polymer but is susceptible to cracking, delamination, oxidation, and moisture penetration over time. This study demonstrates that 3D micro‐anchors fabricated by direct laser writing (DLW) greatly enhance PaC lifetime and encapsulation properties. The PaC film is vapor deposited onto these anchor points, followed by ultraviolet radiation (UV)‐curing‐induced shrinkage. Electrochemical impedance spectroscopy (EIS) during accelerated aging tests in reactive solutions (87 °C, 15 mM H2O2) is performed to monitor film degradation over time. Unpatterned PaC films failed before reaching the 3.25 accelerated year benchmark, while 100 µm spaced micro‐anchors extended encapsulation up to 5.5 equivalent years. Subsequent improvements are achieved with a spacing of 50 µm, demonstrating viability up to ≈6 equivalent years. This research demonstrates the benefit of engineering anchor points for preventing delamination of the PaC layer and significantly enhancing encapsulation properties. Printed 3D micro‐anchors are an extremely flexible platform, with many different shapes and sizes possible which can further enhance longevity. The success in increasing coating lifetimes offers a promising direction for improving long‐term implantable medical devices, potentially revolutionizing their longevity and reliability.
Electrically Reconfigurable Phase‐Change Transmissive Metasurface
Authors: Popescu Cosmin Constantin , Aryana Kiumars , Garud Parth , Dao Khoi Phuong , Vitale Steven , Liberman Vladimir , Bae Hyung‐Bin , Lee Tae‐Woo , Kang Myungkoo , Richardson Kathleen A. , Julian Matthew , Ocampo Carlos A. Ríos , Zhang Yifei , Gu Tian , Hu Juejun , Kim Hyun Jung 
Published: May 2024

AbstractProgrammable and reconfigurable optics hold significant potential for transforming a broad spectrum of applications, spanning space explorations to biomedical imaging, gas sensing, and optical cloaking. The ability to adjust the optical properties of components like filters, lenses, and beam steering devices could result in dramatic reductions in size, weight, and power consumption in future optoelectronic devices. Among the potential candidates for reconfigurable optics, chalcogenide‐based phase change materials (PCMs) offer great promise due to their non‐volatile and analogue switching characteristics. Although PCM have found widespread use in electronic data storage, these memory devices are deeply sub‐micron‐sized. To incorporate phase change materials into free‐space optical components, it is essential to scale them up to beyond several hundreds of microns while maintaining reliable switching characteristics. This study demonstrated a non‐mechanical, non‐volatile transmissive filter based on low‐loss PCMs with a 200 × 200 µm2switching area. The device/metafilter can be consistently switched between low‐ and high‐transmission states using electrical pulses with a switching contrast ratio of 5.5 dB. The device was reversibly switched for 1250 cycles before accelerated degradation took place. The work represents an important step toward realizing free‐space reconfigurable optics based on PCMs.
Boosting Upconversion Efficiency in Optically Inert Shelled Structures with Electroactive Membrane through Electron Donation
Authors: Wang Liu‐Chun , Chen Hong‐Kai , Wang Wen‐Jyun , Hsu Fang‐Yi , Huang Hong‐Zhang , Kuo Rui‐Tong , Li Wei‐Peng , Tian Hong‐Kang , Yeh Chen‐Sheng 
Published: May 2024

AbstractThis study innovatively addresses challenges in enhancing upconversion efficiency in lanthanide‐based nanoparticles (UCNPs) by exploiting Shewanella oneidensis MR‐1, a microorganism capable of extracellular electron transfer. Electroactive membranes, rich in c‐type cytochromes, are extracted from bacteria and integrated into membrane‐integrated liposomes (MILs), encapsulating core–shelled UCNPs with an optically inactive shell, forming UCNP@MIL constructs. The electroactive membrane, tailored to donate electrons through the inert shell, independently boosts upconversion emission under near‐infrared excitation (980 or 1550 nm), bypassing ligand‐sensitized UCNPs. The optically inactive shell restricts energy migration, emphasizing electroactive membrane electron donation. Density functional theory calculations elucidate efficient electron transfer due to the electroactive membrane hemes' highest occupied molecular orbital being higher than the valence band maximum of the optically inactive shell, crucial for enhancing energy transfer to emitter ions. The introduction of a SiO2 insulator coating diminishes light enhancement, underscoring the importance of unimpeded electron transfer. Luminescence enhancement remains resilient to variations in emitter or sensitizing ions, highlighting the robustness of the electron transfer‐induced phenomenon. However, altering the inert shell material diminishes enhancement, emphasizing the role of electron transfer. This methodology holds significant promise for diverse biological applications. UCNP@MIL offers an advantage in cellular uptake, which proves beneficial for cell imaging.
Capacitorless Two‐Transistor Dynamic Random‐Access Memory Cells Comprising Amorphous Indium–Tin–Gallium–Zinc Oxide Thin‐Film Transistors for the Multiply–Accumulate Operation
Authors: Ryu Seungho , Kang Mingu , Cho Kyoungah , Kim Sangsig 
Published: May 2024

AbstractCapacitorless two‐transistor (2T0C) dynamic random‐access memory (DRAM) cells comprising oxide thin‐film transistors (TFTs) show potential as low‐power and high‐density DRAM cells; however, the multiply–accumulate (MAC) operation using these cells is not yet realized. In this study, 2T0C DRAM cells comprising amorphous indium–tin–gallium–zinc oxide TFTs are fabricated for MAC operations. In a 2T0C DRAM cell, one transistor acts as a write transistor and the other as a read transistor, whose gate capacitance corresponds to the data storage capacitance. The cells have a long retention time of 1000 s, which is 104 times longer than that of conventional DRAM cells, owing to the extremely low leakage current of the TFTs (1.11 × 10−18 A µm−1). These cells satisfy the original condition for synaptic devices, in which a proportional relationship exists between the input and output. The MAC operation is performed using two cells. This study demonstrates the usefulness of oxide TFTs in artificial neural networks.
Thickness‐Dependent Formation Capacity and Mechanism of Planar (β)‐Conformation in Polydiarylfluorenes for Stable Deep‐Blue Polymer Light‐Emitting Diodes
Authors: Xu Man , Li Hao , Ma Jingyao , Zhang Yunlong , Chen Wenyu , Wang Shengjie , Lin Jinyin , Feng Quanyou , Xie Linghai 
Published: May 2024

AbstractConjugated polymers with p‐orbital overlap show intramolecular‐conformation‐dependent photophysical and electrical properties. Compared to the non‐planar segments, the planar conformation segments have a relatively long effective conjugated length and rigid backbone structure, which are beneficial for the enhancement of optoelectronic properties. Herein, the effect of film thickness on the formation capacity of planar (β) conformations in polyfluorene (poly[4‐(octyloxy)‐9,9‐diphenylfluorene‐2,7‐diyl]‐co‐[5‐(octyloxy)‐9,9‐diphenylfluorene‐2,7‐diyl], PODPF) for the fabrication of stable deep‐blue polymer light‐emitting diodes (PLEDs) is explored. Thickness‐tunable films with thicknesses ranging from 15 to 270 nm by controlling the concentration of precursor solution are prepared. The main observations are as follows. The PODPF chains in thin films are less likely to adopt the β conformations associated with the loose interchain packing in nano‐aggregates than those in thick films. Red‐shifted and well‐resolved emission spectra are observed for the annealed film with a high thickness, indicating the greater presence of β‐conformation segments. More interestingly, interchain aggregation is a necessary but not sufficient condition for the formation of β conformations. Finally, PLEDs based on β‐conformation segments have outstanding brightness, low turn‐on voltage, and stable deep‐blue electroluminescent behavior, confirming the unique advantage of planar conformation for optoelectronic applications.
Carboxylesterase Activatable Molecular Probe for Personalized Treatment Guidance by Analyte‐Induced Molecular Transformation
Authors: Li Benhao , Liu Hengke , Zhao Mengyao , Zhang Xinming , Huang Peng , Chen Xiaoyuan , Lin Jing 
Published: May 2024

AbstractAccurate visualization of tumor microenvironment is of great significance for personalized medicine. Here, we develop a near‐infrared (NIR) fluorescence/photoacoustic (FL/PA) dual‐mode molecular probe (denoted as NIR−CE) for distinguishing tumors based on carboxylesterase (CE) level by an analyte‐induced molecular transformation (AIMT) strategy. The recognition moiety for CE activity is the acetyl unit of NIR−CE, generating the pre‐product, NIR−CE−OH, which undergoes spontaneous hydrogen atom exchange between the nitrogen atoms in the indole group and the phenol hydroxyl group, eventually transforming into NIR−CE−H. In cellular experiments and in vivo blind studies, the human hepatoma cells and tumors with high level of CE were successfully distinguished by both NIR FL and PA imaging. Our findings provide a new molecular imaging strategy for personalized treatment guidance.
Fabrication of sulfobutylether‐β‐cyclodextrin/glabridin inclusion complex for promoting bioactivities
Authors: Wang Wanru , Tang Kewen , Huang Chenggang , Liu An 
Published: May 2024

AbstractAs the main active compound of Glycyrrhiza glabra L., glabridin (GLD) has been shown to have multiple bioactivities, whereas the clinical application of GLD is restricted by its low water solubility. In this study, GLD was encapsulated into a sulfobutylether‐β‐cyclodextrin (SBE‐β‐CD)‐based inclusion complex (SBE‐β‐CD/GLD) by the freeze‐drying method. The materials characterization, antibacterial activity, stimulated cellular behavior and in vivo full‐thickness diabetic wound healing ability of the hydrogels were assessed and analyzed. The successful encapsulation of the inclusion complex was confirmed by ultraviolet (UV) visible spectroscopy, Fourier transform infrared (FT‐IR), X‐ray diffractometer (XRD), scanning electron microscope (SEM), and nuclear magnetic resonance (NMR). SBE‐β‐CD as an excipient significantly enhances the water solubility of GLD, and SBE‐β‐CD/GLD showed excellent biocompatibility on human vascular endothelial cells (HUVECs) and erythrocytes. The SBE‐β‐CD/GLD inclusion complex exerted a pronounced antibacterial activity on Staphylococcus aureus and Escherichia coli in vitro. The SBE‐β‐CD/GLD inclusion complex markedly enhanced the antioxidant activity compared with free GLD. The SBE‐β‐CD/GLD inclusion complex potently accelerates the healing of full‐thickness skin defects by inhibiting inflammation. The outcomes suggest that SBE‐β‐CD could be used as a promising drug delivery system for the clinical application of GLD.
(Ca0.5Mn0.5)2MnTeO6 – An Anomalously Stable High‐Pressure Double Perovskite
Authors: Almadhi Azizah , Ji Kunlang , Injac Sean D. , Ritter Clemens , Attfield J. Paul 
Published: May 2024

AbstractHigh pressure high temperature treatments of the composition CaMnMnTeO6 are found to yield only an A2BB’O6‐type double perovskite (Ca0.5Mn0.5)2MnTeO6, rather than a AA'BB’O6 double double perovskite with A‐ and B‐ site cation order as found in analogs CaMnMnReO6 and CaMnMnWO6 with similar cation sizes. Double perovskite (Ca0.5Mn0.5)2MnTeO6 adopts a monoclinic structure in space group P21/n with a framework of highly tilted MnO6 and TeO6 octahedra enclosing disordered Ca2+ and Mn2+ cations. Magnetic measurements show that (Ca0.5Mn0.5)2MnTeO6 is a highly frustrated spin glass with a freezing transition at 5 K, and no long‐range spin order is apparent by neutron diffraction at 1.6 K.
Exploring the Impact of Decoys on Decision‐Making by Young Children
Authors: Parrish Audrey E. , Dawes Jillian , Thompson Hannah L. 
Published: May 2024

ABSTRACTThe asymmetric dominance effect (or decoy effect) is a decision‐making phenomenon that occurs when preference for a target alternative shifts with the addition of a similar, yet inferior alternative dubbed the decoy. Despite the considerable number of studies examining the decoy effect with adult humans and animals, there is comparatively less research on context effects within the developmental domain. In this study, we explored the impact of a decoy on choice behavior by young children (3–9 years old) using a preferential choice task as well as a perceptual discrimination task. Introduction of an inferior decoy impacted choice behavior across 2‐alternative (binary) versus 3‐alternative (trinary) sets, such that inclusion of the dominated decoy in expanded sets decreased selection of the superior target alternative. This pattern of results indicates a reversal of the standard attraction effect, also known as the repulsion effect. We discuss these findings in light of the adult and comparative literatures on decoy effects as well as call for additional developmental studies exploring the impact of inferior alternatives in multialternative decision‐making.
The effect of variable delays to reinforcement on the acquisition of tacts in children with autism
Authors: Yang Ya‐Chien , Wilder David A. , Fernand Jonathan K. , McChristie Ashlyn 
Published: May 2024

AbstractBasic research suggests that reinforcer immediacy is important; even short delays to reinforcement may impair learning. Further, a previous applied study showed that most participants with autism spectrum disorder (ASD) acquired tacts more quickly with immediate reinforcement, compared to delays of 6 and 12 s. However, no research has examined variable delays to reinforcement, which may be more common than fixed delays in applied settings. In this study, we examined the effect of variable delays to reinforcement on the acquisition of tacts. Specifically, we evaluated three conditions: a 0 s delay, a 4–8 s delay, and a 10–14 s delay to reinforcement among three children with ASD. The results show that two of the three participants achieved the mastery criterion most quickly in the 0 s delay condition. We discuss the results and implications of this finding.
Efficient production of human interleukin‐3 from Escherichia coli using protein disulfide isomerase b'a' domain
Authors: Nguyen Thi Kieu Oanh , Ryu Dayoung , Nguyen Minh Quan , Ta Huynh Kim Khanh , Vu Thi Luong , Choe Han 
Published: May 2024

AbstractHuman interleukin‐3 (IL3) is a multifunctional cytokine essential for both clinical and biomedical research endeavors. However, its production in Escherichia coli has historically been challenging due to its aggregation into inclusion bodies, requiring intricate solubilization and refolding procedures. This study introduces an innovative approach employing two chaperone proteins, maltose binding protein (MBP) and protein disulfide isomerase b'a' domain (PDIb'a'), as N‐terminal fusion tags. Histidine tag (H) was added at the beginning of each chaperone protein gene for easy purification. This fusion of chaperone proteins significantly improved IL3 solubility across various E. coli strains and temperature conditions, eliminating the need for laborious refolding procedures. Following expression optimization, H‐PDIb'a'‐IL3 was purified using two chromatographic methods, and the subsequent removal of the H‐PDIb'a' tag yielded high‐purity IL3. The identity of the purified protein was confirmed through liquid chromatography coupled with tandem mass spectrometry analysis. Biological activity assays using human erythroleukemia TF‐1 cells revealed a unique two‐step stimulation pattern for both purified IL3 and the H‐PDIb'a'‐IL3 fusion protein, underscoring the protein's functional integrity and revealing novel insights into its cellular interactions. This study advances the understanding of IL3 expression and activity while introducing novel considerations for protein fusion strategies.
Enabling organizations to strategically manage risks in circular supply chains
Authors: Krstić Mladen , Agnusdei Leonardo , Palmi Pamela , Baležentis Tomas 
Published: May 2024

AbstractCircular supply chains (CSCs) prioritize resource efficiency by reusing, remanufacturing, and recycling materials, offering environmental benefits and competitive advantages. However, they are facing various risks and organizational challenges that hinder their efficiency. To ensure long‐term sustainability, this study identifies the key risks and introduces a prioritization model for risk management in CSC strategies proposing a framework for the risk evaluation based on the set of criteria and prioritization model using a combination of three multicriteria decision‐making (MCDM) methods. The model applies fuzzy Delphi‐based analytical hierarchy process (AHP) method to determine the criteria weights and fuzzy axial distance‐based aggregated measurement (ADAM) method for ranking the alternatives. The findings of this study allow for the identification of the most important risks associated with CSC enabling stakeholders to allocate resources strategically and focus efforts on crucial areas. Results highlight that the most important risks are supply chain complexity, resource availability, and quality and technological challenges. The most important contributions are the identification of the most relevant risks that threaten the resilience and sustainability of CSCs, the establishment of the framework for their evaluation, and the development of a novel hybrid MCDM model for their ranking. These contributions are also the main theoretical implications of the study. On a practical level, it enables organizations to strategically manage risks, standardize risk assessment, and improve their competitive advantage by enhancing resilience, reducing disruptions, and lowering operational costs.