bluuebunny/crossref_metadata_2025_split huggingface dataset:
Untersuchungen zum Auslaugverhalten beregneter Bauteile
Authors: Vollpracht Anya , Brameshuber Wolfgang 
Published: July 2009

AbstractIn diesem Beitrag werden Ergebnisse zur Auslaugung von Spurenelementen aus mineralischen Baustoffen bei Beregnung dargestellt. Die Auslaugung im Beregnungsversuch wird mit der Auslaugung bei durchgehender Wasserbeaufschlagung verglichen, um festzustellen, welche Relevanz das Beregnungsszenario für die Bewertung der Umweltverträglichkeit von mineralischen Baustoffen hat.Investigations on the leaching behaviour of construction elements exposed to artificial rain.In this paper, results regarding the leaching of trace elements out of mineral building materials under irrigation are presented. The leaching in the irrigation test is compared to the leaching under constant water exposure to determine the relevance of the irrigation scenario for the assessment of the environmental compatibility of mineral building materials.
The association between socioeconomic status and exposure to mobile telecommunication networks in children and adolescents
Authors: Thomas Silke , Heinrich Sabine , Kühnlein Anja , Radon Katja 
Published: July 2009

AbstractA potential association between socioeconomic status (SES) and self‐reported use of mobile phones has been investigated in a few studies. If measured exposure to mobile phone networks differs by SES in children, it has not yet been studied. Interview data of 1,481 children and 1,505 adolescents on participants' mobile phone use, socio‐demographic characteristics and potential confounders were taken from the German MobilEe‐study. Sociodemographic data was used to stratify participants into three “status groups” (low, middle, high). Using a personal dosimeter, we obtained an exposure profile over 24 h for each of the participants. Exposure levels during waking hours were expressed as mean percentage of the reference level. Children with a low SES were more likely to own a mobile phone (OR 2.1; 95% CI: 1.1–3.9) and also reported to use their mobile phone longer per day (OR 2.4; 95% CI: 1.1–5.4) than children with a high SES. For adolescents, self‐reported duration of mobile phone use per day was also higher with a low SES (OR: 3.4; 95% CI: 1.4–8.4) compared with a high SES. No association between SES and measured exposure to mobile telecommunication networks was seen for children or adolescents. Mobile phone use may differ between status groups with higher use among disadvantaged groups. However, this does not result in higher overall exposure to mobile telecommunication networks. Whether short duration of own mobile phone use or the small numbers of participants with a low SES are causal, have to be investigated in further studies. Bioelectromagnetics 31:20–27, 2010. © 2009 Wiley‐Liss, Inc.
The effect of the side chain length of Asp and Glu on coordination structure of Cu2+ in a de novo designed protein
Authors: Shiga Daigo , Nakane Daisuke , Inomata Tomohiko , Masuda Hideki , Oda Masayuki , Noda Masanori , Uchiyama Susumu , Fukui Kiichi , Takano Yu , Nakamura Haruki , Mizuno Toshihisa , Tanaka Toshiki 
Published: July 2009

AbstractMetal ions in proteins are important not only for the formation of the proper structures but also for various biological activities. For biological functions such as hydrolysis and oxidation, metal ions often adopt unusual coordination structures. We constructed a stable scaffold for metal binding to create distorted metal coordination structures. A stable four stranded α‐helical coiled‐coil structure was used as the scaffold, and the metal binding site was in the cavity created at the center of the structure. Two His residues and one Asp or Glu residue were used to coordinate the metal ions, AM2D and AM2E, respectively. Cu2+ bound to AM2D with an equatorial planar coordination structure with two His, one Asp, and H2O as detected by electron spin resonance and UV spectral analyzes. On the other hand, Cu2+ had a slightly distorted square planar structure when it bound two His and Glu in AM2E, due to the longer side‐chain of the Glu residue as compared to the Asp residue. Computational analysis also supported the distorted coordination structure of Cu2+ in AM2E. This construct should be useful to create various coordinations of metal ions for catalytic functions. © 2009 Wiley Periodicals, Inc. Biopolymers 91: 907–916, 2009.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Mechanism of pH‐sensitive polymer‐assisted protein refolding and its application in TGF‐β1 and KGF‐2
Authors: Huang Zhifeng , Ni Chunyan , Zhou Xiangtian , Liu Yanlong , Tan Yi , Xiao Jian , Feng Wenke , Li Xiaokun , Yang Shulin 
Published: July 2009

AbstractRefolding of proteins at high concentrations often results in non‐productive aggregation. This study, through a unique combination of spectroscopic and chromatographic analyzes, provides biomolecular evidence to demonstrate the ability of Eudragit S‐100, a pH‐responsive polymer, to enhance refolding of denatured‐reduced lysozyme at high concentrations. The addition of Eudragit in the refolding buffer significantly increases lysozyme refolding yield to 75%, when dilution refolding was conducted at 1 mg/mL lysozyme. This study shows evidence of an electrostatic interaction between oppositely charged lysozyme and the Eudragit polymer during refolding. This ionic complexing of Eudragit and lysozyme appears to shield exposed hydrophobic residues of the lysozyme refolding intermediates, thus minimizing hydrophobic‐driven aggregation of the molecules. Importantly, results from this study show that the Eudragit‐lysozyme bioconjugation does not compromise refolded protein structure, and that the polymer can be readily dissociated from the protein by ion exchange chromatography. The strategy was also applied to refolding of TGF‐β1 and KGF‐2. © 2009 American Institute of Chemical Engineers Biotechnol. Prog. 2009
Virtual angioscopy assessment for acute type B aortic dissection endovascular repair
Authors: Izquierdo, Luis , Leiva, Luis 
Published: July 2009

AbstractIntroduction: Virtual angioscopy 3D reconstruction (VA) based on Multidetector computed tomography (m‐CT) can be an important tool in endovascular aortic repair assessment. Here, we present a case of an acute type B aortic dissection, evaluated with preoperative virtual angioscopy 3D reconstruction (VA). Case Report: A 60 years‐old‐man presented with type B acute aortic dissection. Due to renal malperfusion and uncontrolled hypertension TEVAR and renal stenting was performed based on m‐CT and VA images. Discussion: Aortic dissection endovascular repair requires an accurate evaluation based on M‐CT or magnetic resonance angiography (MRA). VA is a CT‐based 3D reconstruction that provides a sort of information comparable to intravascular ultrasound (IVUS) that can be very helpful when it is not available and has many other potential applications in vascular surgery. © 2009 Wiley‐Liss, Inc.
Outcome in high risk patients with unprotected left main coronary artery stenosis treated with percutaneous coronary intervention
Authors: Jensen Lisette Okkels , Kaltoft Anne , Thayssen Per , Tilsted Hans Henrik , Christiansen Evald Hoej , Mikkelsen Kirsten Vilain , Maeng Michael , Hansen Knud Noerregaard , Villadsen Anton Boel , Madsen Morten , Lassen Jens Flensted , Pedersen Knud Erik , Thuesen Leif 
Published: July 2009

AbstractObjective: We examined mortality, risk of myocardial infarction (MI), and target lesion revascularization (TLR) in high‐risk patients with unprotected left main (LM) percutaneous coronary intervention (PCI) in Western Denmark. Background: PCI of left main coronary artery lesions may be an alternative to coronary artery bypass grafting in high‐risk surgical patients. Methods: From January 2005 to May 2007, all patients who had unprotected LM PCI with stent implantation were identified in the Western Denmark Heart Registry. The indications for PCI were: (1) ST segment elevation MI (STEMI), (2) non‐STEMI (NSTEMI) or unstable angina, and (3) stable angina. All patients were followed up for 18 months. Results: A total of 344 patients were treated with LM PCI (STEMI: 71, NSTEMI/unstable angina: 157, and stable angina: 116). In STEMI patients, the median logistic EuroSCORE was 22.5 (interquartile range 12.5–39.5), in non‐STEMI (NSTEMI)/unstable angina patients 13.8 (4.8–23.9), and in stable angina patients 4.8 (2.2–10.4). Mortality after 18 months 38.0, 18.5, and 11.2% (P < 0.001) in patients with STEMI, NSTEMI/unstable angina, and stable angina, respectively. MI after 18 months was 9.9, 6.4, and 6.0% (P = ns), respectively. Four subacute and one late definite stent thrombosis were seen. TLR occurred in 5.6, 4.5, and 6.9% (P = ns) of patients, respectively. Conclusion: After PCI, patients with STEMI and LM culprit lesion have a high‐mortality risk, whereas long‐term outcome for patients with NSTEMI and stable angina pectoris is comparable with other high surgical risk patients with unprotected left main lesion. Further, TLR rates and risk of stent thrombosis were low. © 2009 Wiley‐Liss, Inc.
Influence of obstructive sleep apnea and treatment with continuous positive airway pressure on fractional flow reserve measurements for coronary lesion assessment
Authors: Mak Gary S. , Kern Morton J. , Patel Pranav M. 
Published: July 2009

AbstractObstructive sleep apnea (OSA) and sleep‐disordered breathing have been implicated in the progression of cardiovascular disease and with increased risk of coronary artery disease, congestive heart failure, and stroke. Fractional flow reserve (FFR) is used to evaluate the physiological significance of coronary artery stenosis, and this technique is largely thought to be independent of systemic hemodynamic changes. Herein, we describe a case of OSA and sleep‐disordered breathing cyclically altering FFR measurements from normal to abnormal in a patient with coronary artery disease. More specifically, we show that the abnormal FFR across a coronary lesion in a patient with sleep disordered apnea improves (to a normal threshold) with the initiation of continuous positive airway pressure (CPAP). This finding may have implications for the mechanisms of cardiac dysfunction in patients with OSA. © 2009 Wiley‐Liss, Inc.
Racial differences in colorectal cancer survival in the Detroit Metropolitan area
Authors: Yan Ben , Noone Anne‐Michelle , Yee Cecilia , Banerjee Mousumi , Schwartz Kendra , Simon Michael S. 
Published: July 2009

AbstractBACKGROUND:Colorectal carcinoma is the second most common cause of cancer death with African Americans having lower survival compared with White Americans. The purpose of this study was to investigate the effect of demographics, clinical factors, and socioeconomic status (SES) on racial disparities in colorectal cancer survival in the Detroit Metropolitan Area.METHODS:The study population included 9078 individuals with primary invasive colorectal cancer identified between 1988 and 1992 through the Surveillance, Epidemiology, and End Results (SEER) program. Demographics, clinical information, and survival were obtained through SEER. SES was categorized using occupation, educational level, and poverty status at the census tract level. Kaplan‐Meier survival curves and Cox proportional hazards regression were used to compare overall survival by race.RESULTS:African Americans were more likely to be diagnosed with stage IV disease (P < .001), and to reside within poor census tracts (P < .001) compared with White Americans. Unadjusted analysis showed that African Americans had a significantly higher risk of death compared with their White American counterparts (hazards ratio [HR], 1.13; 95% confidence interval [CI], 1.07‐1.20). After adjusting for age, marital status, sex, SES group, TNM stage, and treatment, race was no longer significantly associated with overall survival (HR, 1.00; 95% CI, 0.92‐1.09). Similar results were seen with colorectal cancer‐specific survival.CONCLUSIONS:Racial disparities in colorectal cancer survival dissipate after adjusting for other demographic and clinical factors. These results can potentially affect medical guidelines regarding screening and treatment, and possibly influence public health policies that can have a positive impact on equalizing racial differences in access to care. Cancer 2009. © 2009 American Cancer Society.
Alcohol consumption, finasteride, and prostate cancer risk
Authors: Gong Zhihong , Kristal Alan R. , Schenk Jeannette M. , Tangen Catherine M. , Goodman Phyllis J. , Thompson Ian M. 
Published: July 2009

AbstractBACKGROUND:Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, the authors examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with the risk of total, low‐grade, and high‐grade prostate cancer.METHODS:Data for this study came from the 2129 participants in the Prostate Cancer Prevention Trial (PCPT) who had cancer detected during the 7‐year trial and 8791 men who were determined by biopsy to be free of cancer at the trial end. Poisson regression was used to calculate relative risks (RRs) and 95% confidence intervals (95% CIs) for associations of alcohol intake with prostate cancer risk.RESULTS:Associations of drinking with high‐grade disease did not differ by treatment arm. In combined arms, heavy alcohol consumption (≥50 g of alcohol daily) and regular heavy drinking (≥4 drinks daily on ≥5 days per week) were associated with increased risks of high‐grade prostate cancer (RR, 2.01 [95% CI, 1.33‐3.05] and 2.17 [95% CI, 1.42‐3.30], respectively); less heavy drinking was not associated with risk. Associations of drinking with low‐grade cancer differed by treatment arm. In the placebo arm, there was no association of drinking with risk of low‐grade cancer. In the finasteride arm, drinking ≥50 g of alcohol daily was associated with an increased risk of low‐grade disease (RR, 1.89; 95% CI, 1.39‐2.56); this finding was because of a 43% reduction in the risk of low‐grade cancer attributable to finasteride treatment in men who drank <50g of alcohol daily and the lack of an effect of finasteride in men who drank ≥50 g of alcohol daily (Pinteraction= .03).CONCLUSIONS:Heavy, daily drinking increased the risk of high‐grade prostate cancer. Heavy drinking made finasteride ineffective for reducing prostate cancer risk. Cancer 2009. © 2009 American Cancer Society.
Effects of flow vortex on a chorded mitral valve in the left ventricle
Authors: Yin M. , Luo X. Y. , Wang T. J. , Watton P. N. 
Published: July 2009

AbstractAn Immersed Boundary fluid–structure interaction model is developed to investigate the dynamic behaviour of a prosthetic chorded mitral valve (MV) inside the left ventricle (LV). In order to simulate more realistic physiological flow conditions, in vivo magnetic resonance images of the LV are used to determine the anatomical structure and the motion of the LV. The LV geometry and its motion are incorporated into the dynamic MV model. This model allows us to investigate the influences of the flow vortex generated by the LV motion on the MV dynamics, as well as the impact of the motion of the chordae attachment points (CAPs). Results are compared with two other cases: (i) an LV model with no prescribed motion of the CAPs, (ii) a Tube model in which the LV is replaced by a tube, although the motion of the chordae is incorporated. These special cases enable the influence of the chordae motion and the vortex on the behaviour of the MV to be analysed independently. It is found that when the MV is placed inside a dynamic LV, the chordae and the valve stretch are significantly increased in the commissural region, and the flow field is strongly asymmetric, with a clockwise single vortex appearing after the early rapid filling phase of the diastole. Given that we impose a flow rate boundary condition, the reverse pressure gradient cannot be established and, hence, the valve does not close properly. Clearly, the presence of the flow vortex alone is not strong enough to aid the valve closure. Copyright © 2009 John Wiley & Sons, Ltd.
A Comparative Study of the Structural, Electronic, and Vibrational Properties of NH3BH3 and LiNH2BH3: Theory and Experiment
Authors: Lee Seung Mi , Kang Xiang‐Dong , Wang Ping , Cheng Hui‐Ming , Lee Young Hee 
Published: July 2009

AbstractHerein, we systematically investigate the structural, electronic, and vibrational properties of ammonia borane (NH3BH3, AB) and lithium amidoborane (LiNH2BH3, LAB) through both density functional calculations and experiments. AB and LAB samples are generated and their vibrational spectra are obtained by using Fourier transformed infrared spectroscopy (FTIR). The measured vibrational spectra are in good agreement with the calculated ones. Our calculations show that the Li‐related vibration modes are primarily found in the low‐frequency region (<1000 cm−1), and that the intermolecular interactions significantly influence the vibrational spectra. Electronic structure calculations provide insights into the differences between the binding natures of AB and LAB and their influence on the vibrational properties of these compounds.
Carbohydrate‐Derived 1,3‐Diphosphite Ligands as Chiral Nanoparticle Stabilizers: Promising Catalytic Systems for Asymmetric Hydrogenation
Authors: Gual Aitor , Godard Cyril , Philippot Karine , Chaudret Bruno , Denicourt‐Nowicki Audrey , Roucoux Alain , Castillón Sergio , Claver Carmen 
Published: July 2009

AbstractMetallic Ru, Rh, and Ir nanoparticles were prepared by the decomposition of organometallic precursors under H2 pressure in the presence of 1,3‐diphosphite ligands, derived from carbohydrates, as stabilizing agents. Structural modifications to the diphosphite backbone were found to influence the nanoparticles′ size, dispersion, and catalytic activity. In the hydrogenation of o‐ and m‐methylanisole, the Rh nanoparticles showed higher catalytic activity than the corresponding Ru nanoparticles. The Ir nanoparticles presented the lowest catalytic activity of the series. In all cases, the hydrogenation of o‐methylanisole gave total selectivity for the cis‐product, however, the ee of the product was always less than 6 %. A maximum of 81 % cis‐selectivity was obtained for the hydrogenation of m‐methylanisole, however, no asymmetric induction was observed. These results show that the catalytic activity is affected by a combination of influences from the substrate, the diphosphite ligands, and the metallic nanoparticles.
Identification of adulterants added to beeswax: Estimation of detectable minimum percentages
Authors: Jiménez Juan J. , Bernal José L. , del Nozal Maria J. , Martín Maria T. , Toribio Laura 
Published: July 2009

AbstractThe minimum percentages of adulteration of pure beeswax from Apis mellifera with three paraffins of different melting points and with cow tallow, stearic acid and carnauba wax that can be detected by gas chromatography with flame ionization detection were established. The concentrations of 93 endogenous beeswax compounds such as aliphatic hydrocarbons, olefins, acids, monoesters, alcohols and hydroxyacids were measured in relation to an internal standard (octadecyl octadecanoate) in mixtures of beeswax with the six adulterants; the variation of the concentrations of the compounds with the adulteration percentage was also studied. Percentages higher than 1–4% of each adulterant can be detected in the mixtures. The added adulterant can be identified by the non‐endogenous beeswax compounds observed in the chromatogram; the changes in the concentrations of some beeswax compounds are also useful to corroborate the identification.
Lipid and mineral distribution in different zones of farmed and wild blackspot seabream (Pagellus bogaraveo)
Authors: Álvarez Victoria , Medina Isabel , Prego Ricardo , Aubourg Santiago P. 
Published: July 2009

AbstractLipid composition was studied in different white muscle zones (ventral, dorsal and tail) of wild and farmed blackspot seabream (Pagellus bogaraveo). The study was complemented by moisture, trimethylamine oxide (TMAO) and trace mineral determinations. Farmed fish muscle showed higher lipid and triacylglycerol contents, but lower values for moisture, TMAO and α‐tocopherol than its wild fish counterpart; no differences could be observed between both kinds of fish for the phospholipid, sterol and free fatty acid contents. When compared to wild fish, a higher saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acid (PUFA) content was obtained in farmed fish, while lower values could be observed for the n‐3/n‐6 and 22:6n‐3/20:5n‐3 fatty acid ratios. Most minerals analysed (Cu, Fe, Mn, Se and Zn) showed higher mean values in farmed fish muscle, except for Ca and Mg which provided higher mean contents in wild fish. Concerning the muscle site comparison, greater SFA, MUFA and PUFA contents could be detected in the dorsal zone than in the two other locations both for farmed and wild fish, in accordance with a higher mean lipid content found at this site. Finally, the tail zone showed higher TMAO values than the two other locations.
Protecting oil during frying: A comparative study
Authors: Aladedunye Felix A. , Przybylski Roman 
Published: July 2009

AbstractThe effect of carbon dioxide blanketing (CDB) and vacuum frying (VF) on the frying performance of regular canola oil was evaluated. For 7 h daily and for 7 days French fries were fried in regular canola oil at 185 ± 5 °C without and with CDB and in a vacuum fryer. The extent of changes in the oil was assessed by analysis of total polar compounds (TPC), anisidine value (AV), color component formation and changes in composition of fatty acids and tocopherols. Frying under CDB reduced the amount of TPC by 54%, while 76% reduction was observed during VF compared to standard frying conditions (SFC). Similarly, lower oxidative degradation was observed when measured by AV. At the end of the frying period, the reduction in unsaturated fatty acid content was 3.8, 1.9 and 12.7% when frying under CDB, vacuum and SFC, respectively. The rate of tocopherol degradation was three and twelve times slower in VF when compared to CDB and SFC, respectively.
Enantioselective Halogenation of β‐Oxo Esters Catalyzed by a Chiral Sulfoximine–Copper Complex
Authors: Frings Marcus , Bolm Carsten 
Published: July 2009

AbstractA C1‐symmetric amino sulfoximine has been used as a chiral ligand in copper‐catalyzed asymmetric halogenation reactions of β‐oxo esters. Both the catalyst itself and the reaction conditions were optimized, and 26 fluorinated, chlorinated, and brominated products were obtained with enantioselectivities of up to 91 % ee in yields of up to 99 %. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Isotopic Exchange of Hydrogen at C‐5 in Pyrimidine Derivatives: Tautomers with an sp3‐Hybridised C‐5 Carbon Atom
Authors: Dračínský Martin , Holý Antonín , Jansa Petr , Kovačková Soňa , Buděšínský Miloš 
Published: July 2009

AbstractThe proton‐to‐deuterium exchange reaction of the hydrogen atom at the 5‐position of 15 pyrimidine derivatives has been studied. The exchange proceeds under both acidic and alkaline conditions. Under acidic conditions, the mechanism involves protonation at the 5‐position (forming an σ complex), whereas under alkaline conditions the exchange is mainly a result of the formation of a tautomeric equilibrium, with one tautomer bearing an sp3‐hybridised carbon atom at the 5‐position.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)