bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phase Diagram of Na2S2O3)+t‐Butanol+Water at Ambient Pressure and Temperature
Authors: Sabale Sandip R. 
Published: November 2011

AbstractIn the present work, we report the studies concerning liquid‐liquid‐solid equilibria for the ternary system sodium thiosulphate (Na2S2O3)+t‐butanol+water at ambient pressure and at room temperature (303±2 K). The solubility data of Na2S2O3 are reported for solutions in water, t‐butanol and solutions of varying concentrations of t‐butanol in water. The phase diagram for the said system is developed, described and compared with similar systems studied such as Na2S2O3+ethanol+water, K2CO3+methanol+water, etc. These results have been explained in terms of structural properties of aqueous t‐butanol solutions and further discussed in terms of the effect of ions to cause phase separation.
p53 Negatively Regulates Transcription of the Pyruvate Dehydrogenase Kinase Pdk2
Authors: Contractor Tanupriya , Harris Chris R. 
Published: November 2011

Abstract
In cancer cells, the aberrant conversion of pyruvate into lactate instead of acetyl-CoA in the presence of oxygen is known as the Warburg effect. The consequences and mechanisms of this metabolic peculiarity are incompletely understood. Here we report that p53 status is a key determinant of the Warburg effect. Wild-type p53 expression decreased levels of pyruvate dehydrogenase kinase-2 (Pdk2) and the product of its activity, the inactive form of the pyruvate dehydrogenase complex (P-Pdc), both of which are key regulators of pyruvate metabolism. Decreased levels of Pdk2 and P-Pdc in turn promoted conversion of pyruvate into acetyl-CoA instead of lactate. Thus, wild-type p53 limited lactate production in cancer cells unless Pdk2 could be elevated. Together, our results established that wild-type p53 prevents manifestation of the Warburg effect by controlling Pdk2. These findings elucidate a new mechanism by which p53 suppresses tumorigenesis acting at the level of cancer cell metabolism. Cancer Res; 72(2); 560–7. ©2011 AACR.
Mechanistic Study of the Palladium-Catalyzed Stereoselective Cross-Coupling Reaction of 1,1-Dibromo-3,3,3-trifluoro-2-tosyloxypropene
Authors: Shimizu Masaki , Takeda Youhei , Hiyama Tamejiro 
Published: November 2011

Abstract
We prepared a Pd complex by the oxidative addition of 1,1-dibromo-3,3,3-trifluoro-2-tosyloxypropene to [Pd(PPh3)4]. The atomic distance between Pd and F in the complex was 2.95 Å, which was shorter than the sum of the van der Waals radii, suggesting that Pd–F interaction played an important role in determining the stereochemical outcome of the Pd-catalyzed cross-coupling reaction of the propene.
Preterm Milk Oligosaccharides During the First Month of Lactation
Authors: Gabrielli Orazio , Zampini Lucia , Galeazzi Tiziana , Padella Lucia , Santoro Lucia , Peila Chiara , Giuliani Francesca , Bertino Enrico , Fabris Claudio , Coppa Giovanni V. 
Published: November 2011

OBJECTIVE:Oligosaccharides represent one of the main components of human milk, and they have been assigned important biological functions for newborns. Qualitatively and quantitatively, their presence in milk is strictly related to the expression of the mother's Se and/or Le genes, on the basis of which 4 different milk groups have been described. The aim of the study was to provide new data on the oligosaccharide composition of preterm milk in relation to the 4 groups.METHODS:High-pH anion-exchange chromatography was used to quantify levels of 23 oligosaccharides and lactose in 252 milk samples collected from 63 mothers during the first month of lactation and to identify the 4 milk groups.RESULTS:Substantial differences in oligosaccharide contents were found within the groups and were strictly related to the presence or absence of specific fucosyl-oligosaccharides. The highest concentration was found in group 1 (&gt;20 g/L), the lowest level was found in group 4 (∼10 g/L), and intermediate values were observed in groups 2 and 3. No statistically significant differences in lactose concentrations were observed among the groups.CONCLUSIONS:Our data confirm lower lactose concentrations in preterm milk, compared with term milk, and they provide the first detailed characterization of oligosaccharides in preterm milk, demonstrating important differences in oligosaccharide contents in the 4 groups. These differences might exert an influence on several biological functions that are particularly important for preterm infants and currently are attributed to milk oligosaccharides.
Layered Al‐substituted Cobalt Hydroxides/GO Composites for Electrode Materials of Supercapacitors
Authors: Chen Yanli , Hu Zhongai , Chang Yanqin , Wang Huanwen , Fu Guorui , Jin Xiaoqing , Xie Lijing 
Published: November 2011

AbstractIn this work, Al‐substituted α‐Co(OH)2/GO composites with supercapacitive properties were prepared by chemical co‐precipitated method in which cobalt nitrate and aluminum nitrate were used as the raw material, and graphite oxide was employed as carrier. The as‐prepared materials were characterized by X‐ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and fourier transform infrared spectroscopy (FT‐IR). Cyclic voltammetry (CV) and galvanostatic charge/discharge measurements showed that the Al‐substituted α‐Co(OH)2/GO electrode material had excellent electrochemical capacitance. The specific capacitance of 1137 F·g−1 was achieved in 6 mol/L KOH solution at a current density of 1 A·g−1 within a potential range of 0–0.5 V. Moreover, only 12% losses of the initial specific capacitance were found after 500 cycles at a current density of 1 A·g−1.
Morphometric differentiation of Pseudocalanus minutus populations in the Barents Sea
Authors: Dvoretsky Vladimir G. , Dvoretsky Alexander G. 
Published: November 2011

AbstractDvoretsky VG. and Dvoretsky AG. 2011. Morphometric differentiation of Pseudocalanus minutus populations in the Barents Sea. —Acta Zoologica (Stockholm) 00: 1–12.We investigated spatial variations in the morphometric characteristics (total length of body, lengths of cephalothorax, abdomen and antennules, and their relative proportions) of Pseudocalanus minutus, an abundant copepod species across the Barents Sea in August–September 2007. Females were found to have higher values for the measured parameters than males. The average absolute morphometric characters of both sexes increased from the south to the north. In most cases, parameters were similar in the southern, central, and eastern regions delineated by cluster analyses of oceanographic variables. The morphometric characteristics were strongly correlated with environmental variables in both males and females. Multiple regression analysis showed that temperature together with salinity explained 72–85% (in females) and 38–91% (in males) of the total variations in the log10‐transformed morphometric parameters. According to principal component analysis and discriminant function analysis, two distinct groups could be separated in the Barents Sea. The first group included the copepods from the northern region; the other included populations from the southern, central, and eastern regions. The observed morphological variation can be interpreted as geographical variation connected with hydrological variability.
Self‐Regulated Growth of Large‐Grain Sb2S3 Thin Films for High‐Efficiency Solar Cells
Authors: Chen Shihang , Wang Xiaomin , Chen Xueling , Zhao Yuqi , Dai Guohao , Yang Junjie , Tang Rongfeng , Chen Tao , Hu Pu , Li Jianmin 
Published: June 2024

AbstractAntimony sulfide (Sb2S3) has attracted extensive attention due to its excellent photoelectric characteristics, including a high absorption coefficient (α > 104 cm−1) and a suitable bandgap (≈1.7 eV). However, due to its Q1D (quasi‐1D) structure, numerous deep‐level defects are identified in the Sb2S3 film, limiting the device's performance, and necessitating more efforts to overcome this situation. In this context, an ethanol solvent‐assisted chemical bath deposition (S‐CBD) strategy, a novel high‐quality thin film manufacturing technique is presented that modifies the supersaturation of the precursor solution by varying the boiling point and solvent polarity. This approach enables the effective regulation of the correlation between the crystal nucleation and growth rates, resulting in Sb2S3 films with large grains (≈4.25 µm, 37.5% ethanol), excellent crystallinity, well‐oriented structures (TC(211)/TC(020) = 2.39), low defect density, and prolonged carrier lifetimes (τAve ≈ 12.1 ns). Consequently, the final Sb2S3‐based solar device (FTO/CdS/Sb2S3/Spiro‐OMeTAD/Au) shows significant improvements in both FF (61.63%) and JSC (17.61 mA cm−2), yielding an excellent power conversion efficiency (PCE) of 7.84%. This research gives particular insights into the growth mechanism of high‐quality Sb2S3 thin films by CBD method as well as a potential route for enhancing Sb2S3 solar cell performance.
Advanced Polymer Materials for Protecting Lithium Metal Anodes of Liquid‐State and Solid‐State Lithium Batteries
Authors: Li Zhenghao , Zheng Yun , Liao Can , Duan Song , Liu Xiang , Chen Guohui , Dong Li , Dong Jie , Ma Chunxiang , Yin Bo , Yan Wei , Zhang Jiujun 
Published: June 2024

AbstractLithium metal batteries (LMBs) are considered as one type of the most promising next‐generation energy storage devices with high‐energy‐density, and stabilizing the lithium metal anodes (LMAs) to overcome LMBs’ safety concerns and performance degradation has attracted extensive attention. Introducing advanced polymer materials into the critical components of LMBs has proven to be an effective and promising approach for stabilizing LMAs toward practical application of LMBs. In addressing the lack of a timely review on the emerging progress of advanced polymer materials in LMBs for stabilizing LMAs, a comprehensive article summarizing the most recent developments of multiscale cellulose materials, including micron cellulose (MC) and nanocellulose (NC), in LMBs is reviewed. First, the basic structures of cellulose, characteristics comparison, and the development history of introducing cellulose into LMBs are presented. Furthermore, the roles of multiscale cellulose materials and functional mechanisms in various components of LMBs for stabilizing LMAs are summarized. A general conclusion and a perspective on the current limitations and future research directions of cellulose‐based stable LMBs are proposed. The aim of this review is not only to summarize the recent progress of multiscale cellulose materials in stabilizing LMAs but also to lighten the pathways for realizing LMBs’ practical application.
Chiral Polymer‐Organic Molecule Composite with Circularly Polarized Thermally Activated Delayed Fluorescence and Room‐Temperature Phosphorescence by Bridging Effect of Hydrogen Bond
Authors: Chen Ruilian , Feng Rui , Huang Zhenjie , Feng Dengchong , Long YuBo , Zhang Jiawen , Yang Yuzhao , Ma Zetong , Yuan Zhongke , Lu Shaolin , Zhao Zujin , Chen Xudong 
Published: June 2024

AbstractCircularly polarized luminescence is essential to chiral and photonic science, but achieving circularly polarized thermally activated delayed fluorescence (CP‐TADF) and circularly polarized room‐temperature phosphorescence (CP‐RTP) simultaneously remains a great challenge. This is because it is difficult to satisfy simultaneously the stable triplet exciton, appropriate energy gap, and the regular chiral environment. Herein, a simple strategy is reported to construct a persistent photoluminescent system, which can achieve TADF and RTP simultaneously by suppressing the non‐radiative transition decay of the triplet exciton through intermolecular hydrogen bonding between acridine flavin (AF) and rigid polymer network. The persistent photoluminescent composite exhibited ultra‐long lifetimes and high quantum yields. Then, a rarely multi‐circularly polarized photoluminescence system containing CP‐TADF and CP‐RTP is constructed by the co‐assembly of cellulose nanocrystals, polyvinyl alcohol, and AF. By utilizing the cholesteric structure, photonic band gap of chiral photonic crystals, and the stabilization mechanism of triplet exciton by intermolecular hydrogen bonding between the light emitter and rigid polymer, chiral photoluminescent films exhibited rare optical properties simultaneously: multi‐circularly polarized photoluminescence emission, high and tunable dissymmetric factor, significant quantum yield, and ultralong lifetimes, which are not reported before and broaden the perspective for multi‐circularly polarized luminescence.
Compressively Strained and Interconnected Platinum Cones with Greatly Enhanced Activity and Durability toward Oxygen Reduction
Authors: Liu Mingkai , Zhou Siyu , Figueras‐Valls Marc , Ding Yong , Lyu Zhiheng , Mavrikakis Manos , Xia Younan 
Published: June 2024

AbstractThe synthesis of cone‐shaped Pt nanoparticles featuring compressively‐strained {111} facets by depositing Pt atoms on the vertices of Pd icosahedral nanocrystals, followed by selective removal of the Pd template via wet etching, is reported. By controlling the lateral dimensions down to ca. 3 nm, together with a thickness of ca. 2 nm, the Pt cones show greatly enhanced specific and mass activities toward oxygen reduction, with values being 2.8 and 6.4 times those of commercial Pt/C, respectively. Both the strain field and the observed activity trend are rationalized using density functional theory calculations. With the formation of ultrathin linkers among the Pt cones derived from the same Pd icosahedral seed, the interconnected Pt cones acquire stronger interactions with the carbon support, preventing them from detachment and aggregation during the catalytic reaction. Even after 20 000 cycles of accelerated durability test, the Pt cones still show a mass activity 5.3 times higher than the initial value of the Pt/C.
Optical Switchers to Manipulate Intracellular Pathways and Boost Tissue Regeneration
Authors: Dell’Aversano Natalia , Amenta Maria Laura , Rippa Massimo , Moros Maria , Tino Angela , Tortiglione Claudia 
Published: June 2024

AbstractThe possibility to remotely manipulate intracellular pathways in single cells is among the current goals of regenerative medicine, demanding new strategies to enhance tissue repair and reprogram stem cell activity. Plasmonic nanomaterials are addressing this need, due to improvements in the controlled synthesis allowing convenient regulation and precise thermal positioning. Leveraging on the thermal properties of gold nanoprisms (AuNPs) and on the unparalleled regenerating capabilities of the small invertebrate Hydra vulgaris, here the possibility to activate the molecular machinery underlying the animal regeneration by using AuNPs and applying regular pulses of near infrared irradiation (NIR) is shown. The efficiency of the head regeneration, reproductive capability, and stem cell proliferation rate are boosted by the AuNP photostimulation, indicating NIR triggered hyperthermia as new tool to enhance tissue regeneration. By transcriptional profiling of key developmental genes in animals exposed to external heat or irradiated an estimation of the heat developed in vivo by intracellular nanoheaters is obtained, revealing Hydra as a living thermometer to test performance of plasmonic materials. These results shed light on a novel function of heat emitting nanoparticles to control cell stemness through the activation of molecular pathways that can be targeted for regenerative medicine or wound healing strategies.
Understanding and Design of Cathode–Electrolyte Interphase in High‐Voltage Lithium–Metal Batteries
Authors: Li Wanxia , He Zixu , Jie Yulin , Huang Fanyang , Chen Yawei , Wang Yuan , Zhang Wenqiang , Zhu Xingbao , Cao Ruiguo , Jiao Shuhong 
Published: June 2024

AbstractThe development of lithium–metal batteries (LMBs) has emerged as a mainstream approach for achieving high‐energy‐density energy storage devices. The stability of electrochemical interfaces plays an essential role in realizing stable and long‐life LMBs. Despite extensive and comprehensive research on the lithium anode interface, there is limited focus on the cathode interface, particularly regarding high‐voltage transition metal oxide cathode materials. In this review, the challenges associated with developing stable high‐voltage cathode materials are first discussed. Characterization techniques for understanding the composition and structure of the cathode–electrolyte interphase (CEI) are then introduced. Subsequently, recent developments in electrolyte design and interface modification for constructing a stable CEI are summarized. Finally, perspectives on future research trends for understanding and developing the high‐voltage CEI are discussed. This review can offer valuable guidance for understanding and designing the high‐voltage CEI, pushing forward the development of high‐energy‐density LMBs.
In Situ Interphasial Engineering Enabling High‐Rate and Long‐Cycling Li Metal Batteries
Authors: Li Chenrui , Yang Chengwei , Huang Tianrun , Wang Yuehua , Yang Junhe , Jiang Yong , Mao Jianfeng , Zheng Shiyou , Xia Shuixin 
Published: June 2024

AbstractThe practical implementation of Li metal anode has long been hindered by the significant challenges of notorious dendritic Li growth and severe interphase instability during repeated cycling. Herein, a highly lithiophilic NiSe‐modified host has rationally been constructed to stabilize Li metal by the facile mechanical rolling strategy. The in situ configurated high‐flux Li2Se‐enriched interphase layer can facilitate the fast interfacial charge transfer, high Li plating/stripping reversibility and homogeneous Li nucleation/growth. Consequently, the achieved modified Li metal demonstrates ultrahigh rate capability (10 mA cm−2) and ultralong‐term cycling stability (6600 cycles) with dendrite‐free Li deposition. The Li|LiFePO4 (LFP) cell exhibits an extraordinarily long lifespan cycling stability over 500 cycles with an ultra‐low decay rate of only ≈0.0092% per cycle at 1 C. Furthermore, the 4.5 V high‐voltage Li|LiCoO2 pouch cell with a high areal capacity (≈1.9 mAh cm−2) still reveals an impressively prolonged cyclability over 200 cycles even under the harsh test condition of low negative‐to‐positive‐capacity (N/P) ratio of ≈3.4 and lean electrolyte of ≈5.5 µL mAh−1. This work provides a facile and scalable strategy toward a highly stable Li metal anode for reliable practical usage.
Fasting‐Mimicking Diet Facilitates Anti‐tumor Therapeutic Effects by Nutrient‐Sensitive Nanocomposites
Authors: Wang Zhifang , Wang Junrong , Xu Wencheng , Qiao Luying , Xie Yulin , Gao Minghong , Wang Dongmei , Li Chunxia 
Published: June 2024

AbstractCancer cells support their uncontrolled proliferation primarily by regulating energy metabolism. Inhibiting tumor growth by blocking the supply of nutrients is an effective treatment strategy. Fasting‐mimicking diet (FMD), as a low‐calorie, low‐protein, low‐sugar, high‐fat diet, can effectively reduce the nutrient supply to tumor cells. However, the significant biological barrier presented by the tumor microenvironment imposes greater demands and challenges for drug design. This study constructs the multifunctional nanocomposite ZnFe2O4@TiO2@CHC@Orl‐FA (ZTCOF), which has great potential to overcome the aforementioned drawbacks. ZnFe2O4@TiO2 could produce 1O2 with ultrasound, and stimulate the Fenton‐like conversion of endogenous H2O2 to ·OH, achieving a combined therapeutic effect of sonodynamic therapy (SDT) and chemodynamic therapy (CDT). Orl (Orlistat) and CHC (α‐cyano‐4‐hydroxycinnamic acid) not only block tumor cell energy metabolism but also increase sensitivity to reactive oxygen species, enhancing the cytotoxic effect on tumor cells. Furthermore, combining the treatment strategies with FMD condition control can further inhibit cancer cell energy metabolism, achieving significant synergistic anti‐tumor therapy. Both in vitro and in vivo experiments confirm that ZTCOF with SDT/CDT/starvation can achieve effective tumor suppression and destruction. This work provides theoretical and technical support for anti‐tumor multimodal synergistic therapy.
Effect of Polymer and Cell Membrane Coatings on Theranostic Applications of Nanoparticles: A Review
Authors: Rezaei Bahareh , Harun Asma , Wu Xian , Iyer Poornima Ramesh , Mostufa Shahriar , Ciannella Stefano , Karampelas Ioannis H. , Chalmers Jeffrey , Srivastava Indrajit , Gómez‐Pastora Jenifer , Wu Kai 
Published: June 2024

AbstractThe recent decade has witnessed a remarkable surge in the field of nanoparticles, from their synthesis, characterization, and functionalization to diverse applications. At the nanoscale, these particles exhibit distinct physicochemical properties compared to their bulk counterparts, enabling a multitude of applications spanning energy, catalysis, environmental remediation, biomedicine, and beyond. This review focuses on specific nanoparticle categories, including magnetic, gold, silver, and quantum dots (QDs), as well as hybrid variants, specifically tailored for biomedical applications. A comprehensive review and comparison of prevalent chemical, physical, and biological synthesis methods are presented. To enhance biocompatibility and colloidal stability, and facilitate surface modification and cargo/agent loading, nanoparticle surfaces are coated with different synthetic polymers and very recently, cell membrane coatings. The utilization of polymer‐ or cell membrane‐coated nanoparticles opens a wide variety of biomedical applications such as magnetic resonance imaging (MRI), hyperthermia, photothermia, sample enrichment, bioassays, drug delivery, etc. With this review, the goal is to provide a comprehensive toolbox of insights into polymer or cell membrane‐coated nanoparticles and their biomedical applications, while also addressing the challenges involved in translating such nanoparticles from laboratory benchtops to in vitro and in vivo applications. Furthermore, perspectives on future trends and developments in this rapidly evolving domain are provided.
3D Nanoprinting of Heterogeneous Metal Oxides with High Shape Fidelity
Authors: Hu Huace , Deng Chunsan , Gao Hui , Han Tao , Xue Songyan , Tang Yanting , Zhang Mingduo , Li Minjing , Liu Huan , Deng Leimin , Xiong Wei 
Published: June 2024

Abstract3D nanoprinting can significantly enhance the performance of sensors, batteries, optoelectronic/microelectronic devices, etc. However, current 3D nanoprinting methods for metal oxides are suffering from three key issues including limited material applicability, serious shape distortion, and the difficulty of heterogeneous integration. This paper discovers a mechanism in which imidazole and acrylic acid synergistically coordinate with metal ions in water. Using the mechanism, this work develops a series of metal ion synergistic coordination water‐soluble (MISCWS) resins for 3D nanoprinting of various metal oxides, including MnO2, Cr2O3, Co3O4, and ZnO, as well as heterogeneous structures of MnO2/NiO, Cr2O3/Al2O3, and ZnO/MgO. Besides, the synergistic coordination effect results in a 2.54‐fold increase in inorganic mass fraction within the polymer, compared with previous works, which effectively mitigates the shape distortion of metal oxide microstructures. Based on this method, this work also demonstrates a 3D ZnO microsensor with a high sensitivity (1.113 million at 200 ppm NO2), surpassing the conventional 2D ZnO sensors by tenfold. The method yields high‐fidelity 3D structures of heterogeneous metal oxides with nanoscale resolution, paving the way for applications such as sensing, micro‐optics, energy storage, and microsystems.