bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prototyping and characterisation of 316L stainless steel parts and lattice structures printed via metal fused filament fabrication
Authors: Martignoni Ludovico , Vegro Andrea , Candidori Sara , Shaikh Mohammad Qasim , Atre Sundar V. , Graziosi Serena , Casati Riccardo 
Published: June 2024

Purpose
This study aims to deepen the knowledge concerning the metal fused filament fabrication technology through an analysis of the printing parameters of a commercial 316L stainless steel filament and their influence on the porosity and mechanical properties of the printed parts. It also investigates the feasibility of manufacturing complex geometries, including strut-and-node and triply periodic minimal surface lattices.

Design/methodology/approach
A three-step experimental campaign was carried out. Firstly, the printing parameters were evaluated by analysing the green parts: porosity and density measurements were used to define the best printing profile. Then, the microstructure and porosity of the sintered parts were investigated using light optical and scanning electron microscopy, while their mechanical properties were obtained through tensile tests. Finally, manufacturability limits were explored with reference samples and cellular structures having different topologies.

Findings
The choice of printing parameters drastically influences the porosity of green parts. A printing profile which enables reaching a relative density above 99% has been identified. However, voids characterise the sintered components in parallel planes at the interfaces between layers, which inevitably affect their mechanical properties. Lattice structures and complex geometries can be effectively printed, debinded, and sintered if properly dimensioned to fulfil printing constraints.

Originality/value
This study provides an extensive analysis of the printing parameters for the 316L filament used and an in-depth investigation of the potential of the metal fused filament fabrication technology in printing lightweight structures.
Fostering social media user intentions: AI-enabled privacy and intrusiveness concerns
Authors: Shoukat Muhammad Haroon , Elgammal Islam , Selem Kareem M , Shehata Ali Elsayed 
Published: June 2024

Purpose
This paper aims to empirically examine the impact of psychological factors (i.e. privacy and intrusiveness concerns) on user intentions regarding artificial intelligence (AI)-enabled social commerce applications at their core through perceived usefulness. The theoretical model is supported by the theory of planned behaviour (TPB).

Design/methodology/approach
Data was gathered from 488 social media users in Saudi Arabia.

Findings
Privacy concerns significantly affect perceived usefulness. Furthermore, the link between privacy concerns and behavioural intentions was mediated by perceived usefulness.

Research limitations/implications
Business leaders should raise users’ awareness about the effectiveness of AI-powered tools that can influence their behavioural intentions. Furthermore, managers must be aware of the regulations that protect user privacy, track online activity and offer secure communication channels.

Originality/value
This paper expands on TPB by bridging the theoretical and practical divide. It further develops a theoretical framework for practitioners to better understand customers’ physiological aspects of using AI-powered social commerce platforms.
Challenges and facilitating factors in interorganizational knowledge acquisition: evidence from the Orange Line Metro Train System and Sustainable Bus Rapid Transit Corridor
Authors: Iftikhar Rehab , Javed Sammar 
Published: June 2024

Purpose
This paper aims to identify challenges and facilitating factors in interorganizational knowledge acquisition. For this purpose, the interorganizational settings of the Orange Line Metro Train System and Sustainable bus rapid transit (BRT) Corridor in Pakistan are examined.

Design/methodology/approach
This study uses an exploratory multiple case study approach. The empirical data encompasses semi-structured interviews and archival documents. Within and cross-case analyses are used for analyzing the data.

Findings
The findings identify challenges such as time pressure, knowledge hiding, finding credible information sources, organizational red tape and facilitating factors such as clear objectives, individual interest and personal commitment, and revisiting the organizational culture and environment in which interorganizational knowledge acquisition takes place.

Originality/value
By examining knowledge acquisition in interorganizational projects, this study contributes to the literature on knowledge-based theory.
Differential effects of a social work staffing intervention on social work access among rural and highly rural Veterans: A cohort study
Authors: Honken Andrew N. , Halladay Christopher W. , Wootton Lisa E. , Harmon Alita R. , Hua Cassandra L. , Rudolph James L. , Cornell Portia Y. 
Published: June 2024

AbstractObjectiveTo evaluate the impact on rural Veterans' access to social work services of a Department of Veterans Affairs (VA) national program to increase social work staffing, by Veterans' rurality, race, and complex care needs.Data Sources and Study SettingData obtained from VA Corporate Data Warehouse, including sites that participated in the social work program between October 1, 2016 and September 30, 2021.Study DesignThe study outcome was monthly number of Veterans per 1000 individuals with 1+ social work encounters. We used difference‐in‐differences to estimate the program effect on urban, rural, and highly rural Veterans. Among rural and highly rural Veterans, we stratified by race (American Indian or Alaskan Native, Asian, Black, Native Hawaiian or Other Pacific Islander, and White) and complex care needs (homelessness, high hospitalization risk, and dementia).Data CollectionWe defined a cohort of 740,669 Veterans (32,434,001 monthly observations) who received primary care at a participating site.Principal FindingsAverage monthly social work use was 8.7 Veterans per 1000 individuals. The program increased access by 49% (4.3 per 1000; 95% confidence interval, 2.2–6.3). Rural Veterans' social work access increased by 57% (5.0; 3.6–6.3). Among rural/highly rural Veterans, the program increased social work access for those with high hospitalization risk by 63% (24.5; 18.2–30.9), and for Veterans experiencing homelessness, 35% (13.4; 5.2–21.7). By race, the program increased access for Black Veterans by 53% (6.1; 2.1–10.2) and for Asian Veterans by 82% (5.1; 2.2–7.9).ConclusionsAt rural VA primary care sites with social work staffing below recommended levels, Black and Asian Veterans and those experiencing homelessness and high hospitalization risk may have unmet needs warranting social work services.
Removing barriers: How online visits boost female analysts' participation
Authors: Wang Jun , Wu Chongfeng 
Published: June 2024

AbstractThis study investigates the impact of remote meetings on the participation of female analysts in corporate visits. We find that online visits significantly increase female analysts' participation, especially under greater security risks or work–family conflicts. Additionally, our analysis shows that an increase in the number of female analysts enhances communication between analysts and management and improves forecast performance following corporate visits. These findings suggest that online visits can effectively boost female analysts' participation and enhance their work quality.
IFRS 9 and earnings management in Eurozone banking: The moderating effect of gender diversity
Authors: Proença Catarina , Augusto Mário , Murteira José 
Published: June 2024

AbstractThe present study examines the effect of adopting IFRS 9 on earnings management practices in European Central Bank‐supervised banks, considering the possible moderating effect of gender diversity in this relationship. Using a system GMM methodology, findings suggest IFRS 9 promotes transparency and contributes to a decrease in earnings management, as the new impairment model influences directors' discretion. We also find that gender diversity moderates the negative impact of IFRS 9 on earnings management. However, when the board representation of women is substantial, the adoption of IFRS 9 results in an undesirable turn, as women are more conservative and risk‐averse, which leads to measures of very early prevention of future losses.
Post‐operative pain after single‐visit root canal treatment using resin‐based and bioceramic sealers in teeth with apical periodontitis: A randomised controlled‐trial
Authors: Nathani Tousif Iqbal , Olivieri Juan Gonzalo , Tomás Jordi , Elmsmari Firas , Abella Francesc , Durán‐Sindreu Fernando 
Published: June 2024

AbstractThe present study aimed to compare postoperative pain in teeth with symptomatic and asymptomatic apical periodontitis (AP) following a single‐visit endodontic treatment using BioRoot™ RCS or AH Plus at 8 h, 24 h and 48 h postoperatively. Postgraduate students performed endodontic treatment on 101 teeth with AP, randomised into two obturation groups. A 100‐mm Visual Analog Scale was used to document the intensity of pain at preoperative, 8‐h, 24‐h and 48‐h intervals. The Kolmogorov–Smirnov test was used for normality, and the median and interquartile ranges were compared using the Mann–Whitney U test. Preoperative pain (1.90 ± 3.50) was more frequent in teeth with symptomatic AP (p < 0.05). However, no significant differences were observed in postoperative pain at the 8‐h, 24‐h and 48‐h intervals. Pre and postoperative pain were directly associated (p < 0.05). Single‐visit root canal treatment in teeth with AP using both sealers resulted in similar levels of postoperative pain.
Encapsulated papillary carcinoma of the breast clinicopathological features and management: Could sentinel lymph node biopsy be exempted?
Authors: Ozcan Cumhur , Dag Ahmet , Benli Sami , Tuncel Ferah 
Published: June 2024

AbstractBackgroundPapillary lesions in the breast pose diagnostic and therapeutic challenges. Encapsulated papillary carcinoma (EPC) is a rare breast cancer. However, evidence‐based guidelines are limited. For this reason, there is no complete clarity in diagnosis and treatment management, and there are insufficient studies in the literature. This study aimed to examine the necessity of sentinel lymph node sampling in the management of EPC, in line with patients' clinicopathological data.MethodsWe retrospectively screened patients with EPC in our clinic between January 2012 and March 2022. We recorded and statistically evaluated patients' demographic, clinical, radiological, pathological, and treatment management.ResultsSixty‐four patients with EPCs were identified. The final pathologic evaluation revealed that 19 patients (18.7%) had pure EPC, 27 patients (43.7%) had EPC with associated ductal carcinoma in situ and 18 patients (37.5%) had EPC associated with invasion. The mean age was 61 years, and two patients were male. Breast‐conserving surgery was performed in 62 patients, and simple mastectomy was performed in two patients. Sentinel lymph node biopsy (SLNB) was positive in only one patient. Sixty‐three patients with EPC were hormone receptor‐positive, and one patient was triple‐negative and was associated with invasion. None of the patients died, one had a local recurrence, and a mastectomy was performed.ConclusionsThe overall prognosis and long‐term survival of patients with EPC were excellent. Our study and the current literature indicate that routine SLNB is overtreatment because surgical excision with negative margins is sufficient in EPC cases and lymph node metastasis is rare, even with an invasive component.
JAK inhibitors in refractory dermatomyositis: A case series
Authors: Corbella‐Bagot L. , Bosch‐Amate X. , Gimeno‐Ribes E. , Gil‐Lianes J. , Giavedoni P. , Milisenda J. C. , Prieto‐González S. , Hurtado García R. , Mascaró J. M. 
Published: June 2024

AbstractThis retrospective cohort study assessed the efficacy and safety of Janus kinase (JAK) inhibitors, tofacitinib and baricitinib, in 14 patients with refractory dermatomyositis (DM), a multisystemic autoimmune disorder with limited therapeutic options. Results demonstrated a significant median decrease of 21 points and a 76% reduction in the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) scores, along with a complete resolution of muscular symptoms in 64% of the patients. JAK inhibitors were effective in managing refractory DM across various subtypes with mild and manageable adverse events.
Biomarkers of peanut allergy in children over time
Authors: Foong Ru‐Xin , Du Toit George , van Ree Ronald , Bahnson Henry T. , Radulovic Suzana , Craven Jo , Kwok Matthew , Jama Zainab , Versteeg Serge A. , Brough Helen A. , Logan Kirsty , Perkin Michael R. , Flohr Carsten , Lack Gideon , Santos Alexandra F. 
Published: June 2024

AbstractBackgroundVarious biomarkers are used to define peanut allergy (PA). We aimed to observe changes in PA resolution and persistence over time comparing biomarkers in PA and peanut sensitised but tolerant (PS) children in a population‐based cohort.MethodsParticipants were recruited from the EAT and EAT‐On studies, conducted across England and Wales, and were exclusively breastfeed babies recruited at 3 months old and followed up until 7–12 years old. Clinical characteristics, skin prick test (SPT), sIgE to peanut and peanut components and mast cell activation tests (MAT) were assessed at 12 months, 36 months and 7–12 years. PA status was determined at the 7–12 year time point.ResultsThe prevalence of PA was 2.1% at 7–12 years. Between 3 and 7–12 year, two children developed PA and one outgrew PA. PA children had larger SPT, higher peanut‐sIgE, Ara h 2‐sIgE and MAT (all p < .001) compared to PS children from 12 months onwards. SPT, peanut‐sIgE, Ara h 2‐sIgE and MAT between children with persistent PA, new PA, outgrown PA and PS were statistically significant from 12 months onwards (p < .001). Those with persistent PA had SPT, peanut‐sIgE and Ara h 2‐sIgE that increased over time and MAT which was highest at 36 months. New PA children had increased SPT and peanut‐sIgE from 36 months to 7–12 years, but MAT remained low. PS children had low biomarkers across time.ConclusionsIn this cohort, few children outgrow or develop new PA between 36 months and 7–12 years. Children with persistent PA have raised SPT, peanut‐sIgE, Ara h 2‐sIgE and MAT evident from infancy that consistently increase over time.
“So that we may be counted”
Authors: Farrukhi Ghazal Asif 
Published: June 2024

AbstractIn 2017 a seemingly small change in Pakistan's questionnaire for the upcoming national census sparked vociferous debates about religious identity and the politics of recognition. The questionnaire added “Scheduled Caste” as a separate religion, whereas previously it had appeared as a Hindu subcategory. Some saw this bureaucratic shift as a cynical attempt to further diminish Pakistan's precarious Hindu minority, reopening old wounds about religious nationalism. Anti‐caste progressives, however, saw an opportunity to imagine alternative political horizons for minority citizenship. How do untimely state projects render new political aspirations legible? As shown through ethnographic attention to rumors, enumerative practices, and census campaigns, the tools of bureaucratic documentation can reactivate unsettled histories, helping people imagine new possibilities from the state's margins.
Impact of CYP2D6*2A, CYP2D6*4 and CYP3A5*3 genetic polymorphisms on Bisoprolol peak concentration and clinical response in acute coronary syndrome patients
Authors: Okda Sherouk M. , El‐Bassiouny Noha A. , El Amrawy Ahmed Mahmoud , Salahuddin Ahmad , Elonsy Sohila M. , Kassem Amira B. 
Published: June 2024

AimsAcute coronary syndrome (ACS) represents a major cause of death. Bisoprolol is commonly used in the management of ACS. This study aims to investigate the impact of CYP2D6*2A, CYP2D6*4 and CYP3A5*3 genetic polymorphisms on pharmacokinetics and clinical response of bisoprolol in ACS patients.MethodsThis is an open‐label cohort study that included 127 ACS patients and studied the effect of CYP3A5*3, CYP2D6*2A and CYP2D6*4 genotyping using real‐time polymerase chain reaction on steady state bisoprolol plasma peak concentration analysed by high performance liquid chromatography–fluorescence detector.ResultsRegarding CYP3A5*3, the mean peak bisoprolol concentration for CC, CT and TT genotypes were 4.25 ± 1.20, 3.93 ± 1.10 and 1.79 ± 0.69 ng/mL, respectively (P < .001). Higher systolic (126 ± 5.47 mmHg), diastolic blood pressure (82 ± 2.73 mmHg) and heart rate (97.80 ± 3.03 beats/min) were also observed in CYP3A5*3 TT carriers (P < .05). In CYP2D6*2A, the peak concentration of bisoprolol was lower in CC carriers (3.54 ± 1 ng/mL) compared to GG (4.38 ± 1.25 ng/mL) and GC carriers (4.07 ± 1.29 ng/mL,P = .019). In CYP2D6*4, the mean bisoprolol peak concentration in CC carriers was 3.98 ± 1.31 ng/mL, which was lower than T allele carriers (4.5 ± 0.8,P = .02). No differences in heart rate, systolic, diastolic blood pressure or bisoprolol dose were observed among CYP2D6*2A or CYP2D6*4 variants. Smokers exhibited lower bisoprolol peak concentration (3.96 ± 1.2 ng/mL) compared to nonsmokers (4.55 ± 1.34 ng/mL,P = .037).ConclusionThere is an association between CYP3A5*3, CYP2D6*4, CYP2D6*2A variants and bisoprolol peak concentration, which may serve as a guide in the future in choosing the optimum dose of bisoprolol in ACS patients.
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats
Authors: Bi Guofang , Liang Fengting , Wu Ting , Wang Peng , Jiang Xiaowen , Hu Shuang , Wu Chenghua , Zhou Wenhong , Guo Jiayin , Yang Xiao , Fang Jian‐hong , Chen Wenying , Bi Huichang 
Published: June 2024

AbstractHuman pregnane X receptor (PXR) is critical for regulating the expression of key drug‐metabolizing enzymes such as CYP3A and CYP2C. Our recent study revealed that treatment with rodent‐specific PXR agonist pregnenolone‐16α‐carbonitrile (PCN) significantly induced hepatomegaly and promoted liver regeneration after two‐thirds partial hepatectomy (PHx) in mice. However, it remains unclear whether PXR activation induces hepatomegaly and liver regeneration and simultaneously promotes metabolic function of the liver. Here, we investigated the metabolism activity of CYP1A2, CYP3A1/2 and CYP2C6/11 during PXR activation‐induced liver enlargement and regeneration in rats after cocktail dosing of CYP probe drugs. For PCN‐induced hepatomegaly, a notable increase in the metabolic activity of CYP3A1/2 and CYP2C6/11, as evidenced by the plasma exposure of probe substrates and the AUC ratios of the characteristic metabolites to its corresponding probe substrates. The metabolic activity of CYP1A2, CYP3A1/2 and CYP2C6/11 decreased significantly after PHx. However, PCN treatment obviously enhanced the metabolic activity of CYP2C6/11 and CYP3A1/2 in PHx rats. Furthermore, the protein expression levels of CYP3A1/2 and CYP2C6/11 in liver were up‐regulated. Taken together, this study demonstrates that PXR activation not only induces hepatomegaly and liver regeneration in rats, but also promotes the protein expression and metabolic activity of the PXR downstream metabolizing enzymes such as CYP3A1/2 and CYP2C6/11 in the body.
Outcomes of active surveillance for Japanese patients with prostate cancer (PRIAS‐JAPAN)
Authors: Kato Takuma , Matsumoto Ryuji , Yokomizo Akira , Tohi Yoichiro , Fukuhara Hiroshi , Fujii Yoichi , Mori Keiichiro , Sato Takuma , Inokuchi Junichi , Hashine Katsuyoshi , Sakamoto Shinichi , Kinoshita Hidefumi , Inoue Koji , Tanikawa Toshiki , Utsumi Takanobu , Goto Takayuki , Hara Isao , Okuno Hiroshi , Kakehi Yoshiyuki , Sugimoto Mikio 
Published: June 2024

ObjectiveTo report the outcomes of repeat biopsies, metastasis and survival in the Prostate Cancer Research International: Active Surveillance (PRIAS)‐JAPAN study, a prospective observational study for Japanese patients, initiated in 2010.Patients and MethodsAt the beginning, inclusion criteria were initially low‐risk patients, prostate‐specific antigen (PSA) density (PSAD) <0.2, and ≤2 positive biopsy cores. As from 2014, GS3+4 has also been allowed for patients aged 70 years and over. Since January 2021, the age limit for Gleason score (GS) 3 + 4 cases was removed, and eligibility criteria were expanded to PSA ≤20 ng/mL, PSAD <0.25 nd/mL/cc, unlimited number of positive GS 3 + 3 cores, and positive results for fewer than half of the total number of cores for GS 3 + 4 cases if magnetic resonance imaging fusion biopsy was performed at study enrolment or subsequent follow‐up. For patients eligible for active surveillance, PSA tests were performed every 3 months, rectal examination every 6 months, and biopsies at 1, 4, 7 and 10 years, followed by every 5 years thereafter. Patients with confirmed pathological reclassification were recommended for secondary treatments.ResultsAs of February 2024, 1302 patients were enrolled in AS; 1274 (98%) met the eligibility criteria. The median (interquartile range) age, PSA level, PSAD, and number of positive cores were 69 (64–73) years, 5.3 (4.5–6.6) ng/mL, 0.15 (0.12–0.17) ng/mL, and 1 (1–2), respectively. The clinical stage was T1c in 1089 patients (86%) and T2 in 185 (15%). The rates of acceptance by patients for the first, second, third and fourth re‐biopsies were 83%, 64%, 41% and 22%, respectively. The pathological reclassification rates for the first, second, third and fourth re‐biopsies were 29%, 30%, 35% and 25%, respectively. The 1‐, 5‐ and 10‐year persistence rates were 77%, 45% and 23%, respectively. Six patients developed metastasis, and one patient died from prostate cancer.ConclusionPathological reclassification was observed in approximately 30% of the patients during biopsy; however, biopsy acceptance rates decreased over time. Although metastasis occurred in six patients, only one death from prostate cancer was recorded.
Soil–plant–gall relationships: from gall development to ecological patterns
Authors: Arriola Ígor Abba , Costa Elaine Cotrim , de Oliveira Denis Coelho , Isaias Rosy Mary dos Santos 
Published: June 2024

ABSTRACTThe adaptive nature of the galler habit has been tentatively explained by the nutrition, microenvironment, and enemy hypotheses. Soil attributes have direct relationships with these three hypotheses at the cellular and macroecological scales, but their influence has been restricted previously to effects on the nutritional status of the host plant on gall richness and abundance. Herein, we discuss the ionome patterns within gall tissues and their significance for gall development, physiology, structure, and for the nutrition of the gallers. Previous ecological and chemical quantification focused extensively on nitrogen and carbon contents, evoking the carbon‐nutrient defence hypothesis as an explanation for establishing the plant–gall interaction. Different elements are involved in cell wall composition dynamics, antioxidant activity, and regulation of plant–gall water dynamics. An overview of the different soil–plant–gall relationships highlights the complexity of the nutritional requirements of gallers, which are strongly influenced by environmental soil traits. Soil and plant chemical profiles interact to determine the outcome of plant–herbivore interactions and need to be addressed by considering not only the soil features and galler nutrition but also the host plant's physiological traits. The quantitative and qualitative results for iron metabolism in gall tissues, as well as the roles of iron as an essential element in the physiology and reproduction of gallers suggest that it may represent a key nutritional resource, aligning with the nutrition hypothesis, and providing an integrative explanation for higher gall diversity in iron‐rich soils.