bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migration, culture and mental health
Authors: Murphy H. B. M. 
Published: July 2009

SynopsisThe former belief that immigrants always suffer from an excess of mental disorder is no longer valid, and the old rivalry between social selection and social causation hypotheses has lost much of its relevance. The mental health of a migrant group is determined by factors relating to the society of origin, factors relating to the migration itself, and factors operating in the society of resettlement; and all three sets need to be considered if one seeks to reduce or merely to understand the level of mental disorder in any immigrant group. Illustrations from each set of factors are presented, with indications of whether they appear to have general relevance or be related to specific mental disorders.
Costs and benefits of behavioural psychotherapy: a pilot study of neurotics treated by nurse-therapists
Authors: Ginsberg Gary , Marks Isaac 
Published: July 2009

synopsisA pilot study is reported of costs and benefits from behavioural psychotherapy by nurse-therapists for selected neurotic problems. Figures are based on the treatment of 42 neurotics (mainly phobics and obsessive-compulsives) who completed treatment with nurse-therapists in a mean of 9 sessions (16 hours). The year before and after treatment was studied. Apart from significant and lasting reduction in patients' distress, economic benefits to them, their families and the community yielded a worthwhile internal rate of return when benefits from the cohort continue for 3 years, a reasonable assumption on available other evidence. Though untreated phobics did not improve elsewhere over 5 years follow-up, a controlled study would seem desirable.
Lowered responsiveness and auditory signal detectability during depression
Authors: Malone J. R. L. , Hemsley D. R. 
Published: July 2009

synopsisTen depressed patients were assessed on an auditory signal detection task; testing was repeated on remission. The patients' clinical state was monitored by means of the Hamilton rating scale and the Beck Depression Inventory. The task was performed under three conditions: 2 button (Yes/No); 1 button (Yes); 1 button (No). The findings indicated lower motor responsiveness during depression, consistent with Seligman's learned helplessness model. The measure of auditory sensitivity was also lowered during depression, possibly attributable to attentional disturbance. It is suggested that the lowered initiation of voluntary responses may be an important factor in the assessment of cognitive functioning during depression; such deficits may be reduced if the task does not permit the omission of a response.
Prostaglandins and schizophrenia: further discussion of the evidence
Authors: Horrobin D. F. , Ally A. I. , Karmali R. A. , Karmazyn M. , Manku M. S. , Morgan R. O. 
Published: July 2009

SynopsisIt has been proposed that schizophrenia is a prostaglandin-deficiency disease and also that it is a disease of prostaglandin excess. New evidence is reviewed which suggests that ‘classic’ schizophrenia is due to a specific deficiency of prostaglandin E1while certain toxic and vitamindeficiency psychoses may be due to a broader spectrum of prostaglandin deficiency. There is also good evidence that a particular schizophrenic subgroup, which includes catatonic schizophrenia but may not be confined to it, is associated with an excess of prostaglandins. Part of the explanation may be that prostaglandin E1has a ‘bell-shaped’ dose-response curve with high concentrations having effects similar to those of prostaglandin deficiency.
The relationship between psychological and physiological measures of anxiety
Authors: Morrow Gary R. , Labrum Anthony H. 
Published: July 2009

SynopsisThe responses of 6 representative physiological parameters frequently assumed to be measures of anxiety along with a set of 4 psychological tests for measuring anxiety were obtained under naturalistic conditions from 25 patients hospitalized with a first myocardial infarction. A canonical correlational analysis failed to show any relationship between anxiety as assessed by the Taylor Manifest Anxiety Scale, Mood Adjective Check List, State-Trait Anxiety Inventory and Multiple Affect Adjective Check List psychological tests, and anxiety as assessed by the physiological indices of heart rate, systolic and diastolic blood pressures, epinephrine, norepinephrine and VMA. The intercorrelation matrix revealed a significant positive pattern of relationships among all 4 psychological tests, a non-significant, positive pattern of relationships among the physiological indices, and a non-significant, negative pattern of relationships between the psychological and physiological measures. The absence of mood-specific physiological measures for anxiety, as measured by the psychological tests, supports previous theory and investigation and points to the inadvisability of assuming that studies on anxiety that use diverse physiological and psychological measures yield results that may be compared as though they were assessing a common mood.
Serum folic acid and B12 in 272 psychiatric in-patients
Authors: Carney M. W. P. , Sheffield B. F. 
Published: July 2009

SynopsisSerum folate and B12 estimations were carried out on 272 admissions to a psychiatric unit during 1972 and 1973. 21–3% had serum folate below 2 ng/ml and 26–1% serum B12 below 150 pg/ml. The organic psychosis patients had a significantly lower mean B12 than the others, and were over-represented among the low B12 group. Low B12 status was also associated with low RBC and WBC. Low folate status was linked with depression, malnutrition, physical illness and low Hb, RBC and WBC. There were more chronic alcoholics than others with serum folate > 4·9 ng/ml, low RBC and macrocytosis. The presence of one or more haematological abnormalities (macrocytosis, low Hb, low RBC or low WBC) predicted low folate in 76%, and low B12 in 79%, but these were also found in 40% of the normal folate and 41% of the normal B12 patients. Macrocytosis may prove to be a reliable sign of alcoholic abuse.
Multiple personality: A single case study with a 15 year follow-up
Authors: Cutler Brian , Reed John 
Published: July 2009

SynopsisA review of the literature relating to multiple personality is presented together with a study of a single case of hysterical aetiology that demonstrates the development of multiple personality from a fugue amnesic state. A re-examination of this case after 15 years without significant psychotherapeutic intervention demonstrates a tendency towards remission. The view that multiple personality is a form of fugue, not necessarily hysterical, in which an alternative personality is adopted and that this behaviour is reinforced by the attention that it receives, is discussed.
Depression followed by suicide: a comparison of depressed suicides with living depressives
Authors: Barraclough B. M. , Pallis D. J. 
Published: July 2009

SynopsisThe characteristics of 64 suicides with a retrospective diagnosis of depression and 128 depressives referred for psychiatric treatment were compared. The following items differentiated the suicide group: male sex, older age in females, single status, living alone, the symptoms of insomnia, impaired memory and self neglect, and a history of suicide attempts. The value of these items in assessing suicide risk in depressive illness is discussed.
Effects of maintenance amitriptyline and psychotherapy on symptoms of depression
Authors: Paykel E. S. , Dimascio A. , Haskell D. , Prusoff B. A. 
Published: July 2009

SynopsisDepressives responding to initial treatment were maintained on amitriptyline for eight months, withdrawn double-blind to placebo after two months, or withdrawn overtly onto no medication. In each group half the patients received weekly psychotherapy and half were seen, once monthly. Effects on symptom ratings were examined. Maintenance amitriptyline gave a significant advantage over early withdrawal in preventing symptom recrudescence. There were no differences between double-blind or overt withdrawal. There were no interactions between drug withdrawal and psychotherapy. Psychotherapy produced no significant advantages over low contact on symptoms, although it did improve social adjustment ratings reported elsewhere.
Double-blind procedure: an assessment in a study of lithium prophylaxis
Authors: Stallone F. , Mendlewicz J. , Fieve R. R. 
Published: July 2009

SynopsisFifty-seven patients with primary affective disorder who were in a double-blind outpatient study to evaluate the prophylaxis of lithium were questioned as to whether they believed they were receiving lithium or placebo. Research nurses who were ‘blind’ to the patients' medication and a close relative living with each patient were also questioned. Nearly all patients (96%) said they believed they were receiving lithium, ascribing this belief in 63% of the cases to a perceived improvement in condition. In only 14% of the cases on lithium was the presence of side-effects implicated in the patients' beliefs. One of the three nurses had a correct guess rate in excess of chance expectancy. All nurses tended to be more accurate in their guesses in the cases of patients who had been in prophylactic trials of over 15 months' duration than for patients with briefer periods in the study. Patients' relatives were, as a group, extremely accurate, their correct guess rate exceeding chance expectancy at the 0·001 level.
Tolerance to amphetamine in two species (rat and guinea pig) that metabolize it differently
Authors: Sever Peter S. , Caldwell John , Williams R. Tecwyn 
Published: July 2009

SynopsisIt has been proposed thatp-hydroxynorephedrine, a metabolite of amphetamine, is responsible for the tolerance that occurs to this drug. To test this idea, the development of tolerance to amphetamine has been examined in two species, the rat and the guinea pig, the former of which producesp-hydroxynorephedrine from amphetamine while the latter does not. In both species, tolerance develops to the anorectic and hyperthermic actions of amphetamine, and similar changes in the pattern of behavioural stimulation are seen.
Psychoneurotic disturbance and drug-taking in Borstal boys
Authors: Foggitt R. H. , Gossop M. R. , Nicol A. R. 
Published: July 2009

SynopsisTheir own accounts of their use of drugs, together with a detailed description of psychiatric history and present mental state, were obtained from a sample of institutionalized delinquents, Subjects reporting extensive involvement in drug abuse were found to be disturbed on a number of psychiatric variables; however, those reporting some limited abuse were less disturbed than subjects reporting no experience of drug taking. The results and their implications are discussed.
Magnetic resonance imaging in pre-senile dementia of the Alzheimer-type, multi-infarct dementia and Korsakoff's syndrome
Authors: Christie J. E. , Kean D. M. , Douglas R. H. B. , Engleman H. M. , St. Clair D. , Blackburn I. M. 
Published: July 2009

SynopsisMagnetic resonance imaging T1 values in Alzheimer's disease (ATD) were similar to age-matched controls although frontal T1 values tended to increase intraindividually with progression of the dementia. T1 values were raised, in both cortical grey and white matter, in Korsakoff's syndrome and multi-infarct dementia. T1 values appear of little value in studying the neuropathological changes in ATD in relationship to the neuropsychological deficits, but can assist in the differential diagnosis of pre-senile dementia.
Agenesis of the corpus callosum and schizophrenia: a case report
Authors: Lewis S. W. , Reveley M. A. , David A. S. , Ron M. A. 
Published: July 2009

SynopsisClinical, radiological and neuropsychological findings in the first reported case of schizophrenia with complete agenesis of the corpus callosum are described. Although causal inferences were made difficult by the co-existence of a left frontotemporal cyst and a family history of affective disorder, some theories of the role of callosal dysfunction in schizophrenia require revision in the light of this case.
Psychiatric morbidity in patients with clinically isolated lesions of the type seen in multiple sclerosis: a clinical and MRI study
Authors: Logsdail S. J. , Callanan M. M. , Ron M. A. 
Published: July 2009

SynopsisThis study reports the psychiatric morbidity in 76 patients with clinically isolated lesions of the type seen in multiple sclerosis (optic neuritis, brain stem and cord lesions). The presence or absence of brain pathology was investigated using magnetic resonance imaging (MRI). A group of 33 patients suffering from rheumatic and neurological conditions not known to involve the brain was used for comparison. Normative MRI data were obtained from a group of 40 normal volunteers.Over half of the patients with the clinical presentation of single lesions had MRI abnormalities in the brain, but past and present psychiatric morbidity were similar in patients and controls and no significant associations were found between the presence of MRI abnormalities and psychiatric morbidity. The degree of social stress experienced by the patients with clinically isolated lesions appeared to be highly relevant in the causation of psychiatric symptoms.
Personal networks, support mobilization and unemployment
Authors: Jackson Paul R. 
Published: July 2009

SynopsisMeasures were obtained of features of social network structure and the mobilization of instrumental and expressive support from a sample of 301 unemployed men. Findings showed dependence on a restricted number of family members and close friends, with high levels of expressive support (for example, 71 per cent of the sample reported that someone had ‘let you know that he or she is always around if you need help with something’). Follow-up interviews were obtained on two further occasions over a period of one year, and significant changes in network structure and support mobilization were found. A decrease in non-family network size suggested greater reliance on close family and friends and a withdrawal from weaker ties with members of the community. Finally, the findings of this study emphasize the importance of incorporating a time dimension into research on the mobilization of support following a stressful life event such as job loss.
Needs for care among the long-term mentally ill: a report from the Camberwell High Contact Survey
Authors: Brewin C. R. , Wing J. K. , Mangen S. P. , Brugha T. S. , MacCarthy B. , Lesage A. 
Published: July 2009

SynopsisWe report the results of a survey of the needs for items of care of 145 long-term users of psychiatric day-hospitals and day-centres in Camberwell. The overall ratio of met to unmet need was almost exactly 5:1. Need was shown to vary according to chronicity, degree of participation, and placement in day-hospital or day-centre. Specific areas of functioning and specific types of care were identified in which there was significant overprovision or underprovision. The utility of our measures, and their ability to identify clinically significant unmet need, are discussed.
The use of cholecystokinin in schizophrenia: a review
Authors: Montgomery Stuart A. , Green Mary C. D. 
Published: July 2009

SynopsisCholecystokinin (CCK) is a peptide originally isolated from the gut. It has been investigated as a candidate treatment for schizophrenia on the assumption that the illness is associated with an imbalance between CCK and dopamine in the mesolimbic dopamine system. Many of the studies to assess the efficacy of CCK used open designs and are prone to observer bias and over-optimistic reporting. Most of the studies used CCK as an adjunct to standard neuroleptic treatment and are too small to be able to demonstrate extra efficacy above that of the active compound. Only three out of ten studies using CCK or placebo as an adjunct to neuroleptics reported limited efficacy. Of the 14 placebo-controlled reports only three were in drug-free patients. These were unfortunately too small, or too brief, to draw valid conclusions of efficacy. A summary of these data suggests that although 500 patients have received CCK, its efficacy in the treatment of schizophrenia has not been properly tested.
Abnormal eating attitudes in London schoolgirls — a prospective epidemiological study: factors associated with abnormal response on screening questionnaires
Authors: Johnson-Sabine Eric , Wood Kathryn , Patton George , Mann Anthony , Wakeling Anthony 
Published: July 2009

SynopsisOne thousand and ten unselected London state schoolgirls were screened by questionnaire to identify an ‘at risk’ cohort displaying abnormal eating attitudes and two control cohorts, one with probable general psychiatric morbidity, one without. Members of all cohorts were assessed at interview for the presence of eating disorder and for putative risk factors implicated in the development of anorexia nervosa. A prevalence rate of 0·99 % was detected for clinical eating disorder and 1·78 % for the partial syndrome of eating disorder. Factors specifically associated with abnormal eating attitudes were identified, in particular, current or past overweight, history of amenorrhoea and perceived stress in school and social life. Some commonly accepted risk factors for eating disorders were discovered to be associations with general psychiatric morbidity. These were perceived parental pressure to eat more, taking exercise to lose weight, perceived stress at home and reporting a family history of anxiety or depression. Other well reported putative risk factors for eating disorder, including social class, birth order, age at menarche, obsessional personality and weight related career choice were not associated specifically with abnormal eating attitudes in schoolgirls. These findings represent cross-sectional data at entry into a prospective epidemiological study.
The relationship between body-image and body-fat in adult women
Authors: Brodie D. A. , Slade P. D. 
Published: July 2009

SynopsisMeasures of body-fat or adiposity, body-image, and other psychological variables were obtained from a sample of 100 female volunteer subjects. The measures of adiposity included surface anthropometry, underwater weighing and a new electrical impedance method. Body-image measures were derived from two experimental techniques, namely the visual-size estimation (or calliper) method and a distorting-mirror, and also from a self-report body-satisfaction scale (BSS).The main findings were that measures of adiposity were positively and significantly related to each other. But, that by contrast, measures of body-image separated out into three distinct sets, namely: (i) ‘mirror’ accuracy, (2) ‘callipers’ accuracy, and (3) ‘dissatisfaction/desire for change’. The ‘accuracy’ measures were found to be unrelated to measures of adiposity or other psychological variables: while the ‘dissatisfaction’ measures were found to relate to both of these. The implications of these findings for future studies of weight and eating disorder groups are discussed.
Psychiatric symptoms and related factors in a sample of Japanese workers
Authors: Iwata Noboru , Okuyama Yuko , Kawakami Yoshikazu , Saito Kazuo 
Published: July 2009

SynopsisA survey was conducted to investigate the presence of psychiatric symptoms and associated factors affecting psychiatric impairment among 2190 Japanese tax workers. The Japanese translated version of the General Health Questionnaire (GHQ) was used as a measure of psychiatric symptomatology. Several sociodemographic and psychosocial factors (interpersonal factors and perceived stress) were examined as being related to psychiatric impairment. As with all other language versions, the percentage distribution of the GHQ scores was considerably skewed. Females exhibited more psychiatric symptoms than males. No significant differences were found among four age-groups for both sexes. Perceived stress related to the workplace was correlated more with psychiatric impairment than with other psychosocial factors. It was also observed that the ‘long-distance marriage’ (‘business bachelorhood’) peculiar to Japanese occupations had little influence on the impairment levels.
The Werther effect after television films: new evidence for an old hypothesis
Authors: Schmidtke A. , Häfner H. 
Published: July 2009

SynopsisIn this study it was possible to prove the Werther effect in suicides after watching fictional models for the first time. A twice-broadcast (1981, 1982) six-episode weekly serial showing the railway suicide of a 19-year-old male student provided a quasi-experimental ABABA design to investigate differential effects of suicide imitation. Imitation effects were most clearly observable in the groups whose age and sex were closest to those of the model. Over extended periods (up to 70 days after the first episode), the number of railway suicides increased most sharply among 15- to 19-year-old males (up to 175%); the effect steadily decreased in the older age groups, so that no effect was observable for males over 40 years and females over 30 years. Also, the imitation effects remained detectable for longer periods in the groups closest in age to the model. The increases observed after the first and second broadcast for males aged > 30 years closely corresponded with the respective audience figures for the two showings.
Age and recognition of depression: implications for a cohort effect in major depression
Authors: Hasin Deborah , Link Bruce 
Published: July 2009

SynopsisStudies relying on subjects' retrospective reports have recently been interpreted as indicating that individuals born since World War II are at increased risk for a diagnosis of lifetime major depression. Examining the validity of this ‘cohort effect’ is essential, given the potential importance of such a phenomenon for research and policy. Among a number of artefactual explanations for the cohort effect is the possibility that older individuals are less likely to recognize depression as a mental disorder, and hence are less likely to remember depressive episodes as such, or to report these episodes in interviews on mental health. To test whether age was related to the recognition of major depression as a mental problem, we analysed responses from 152 randomly selected community residents on whether a vignette describing DSM-III major depression represented a psychological or emotional problem. Older respondents were much less likely to characterize major depression this way, even controlling for other factors. Such an age effect may provide a partial explanation for the apparent cohort effect, although the issue is complex and further research is needed.
Obsessive-compulsive beliefs and treatment outcome
Authors: Lelliott P. T. , Noshirvani H. F. , Başoǧlu M. , Marks I. M. , Monteiro W. O. 
Published: July 2009

SynopsisOf 49 compulsive ritualizers one-third perceived their obsessive thoughts as rational and felt that their rituals warded off some unwanted or feared event (the content of their obsessions). The more bizarre the obsessive belief the more strongly it was defended and 12% of cases made no attempt to resist the urge to ritualize. Neither fixity of belief nor resistance to compulsive urges were related to duration of illness. Patients with bizarre and fixed obsessive beliefs responded as well to treatment (all but three received exposure), as did patients whose obsessions were less bizarre and recognized as senseless. There was no difference in outcome between patients who initially found it hard to control their obsessions or never resisted the urge to ritualize and those who initially could control obsessions or resist rituals. One year after starting treatment, patients whose obsessions and compulsions had improved with treatment recognized their irrationality more readily and controlled their compulsive urges more easily. Beliefs appeared to normalize as a function of habituation.