bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated storage assignment for an E-grocery fulfilment centre: accounting for day-of-week demand patterns
Authors: Winkelmann David , Tolkmitt Frederik , Ulrich Matthias , Römer Michael 
Published: June 2024

AbstractIn this paper, we address a storage assignment problem arising in a fulfilment centre of a major European e-grocery retailer. The centre can be characterised as a hybrid warehouse, consisting of a highly efficient and partially automated fast-picking area designed as a pick-and-pass system with multiple stations, and a picker-to-parts area. The storage assignment problem involves the decisions of selecting products to be allocated to the fast-picking area, assigning these products to picking stations, and determining the specific shelves within the designated station. The objective is to achieve high picking efficiency while maintaining balanced workloads across stations and respecting precedence order constraints. We formulate this three-level problem using an integrated mixed-integer linear programming (MILP) model. Computational experiments with real-world data demonstrate that our integrated approach yields significantly better results than a sequential approach, where the selection of products to be included in the fast-picking area is performed before assigning stations and shelves. To enhance computational efficiency, we propose a heuristic solution approach that fixes SKUs to shelves, allowing us to find better solutions in shorter runtimes compared to directly solving the MILP model. Additionally, we extend the integrated storage assignment model to explicitly account for within-week demand variation. In a set of experiments with day-of-week-dependent demands, we show that while a storage assignment based on average demand figures can lead to highly imbalanced workloads on certain days, the augmented model provides well-balanced storage assignments for each day-of-week without compromising the solution quality in terms of picking efficiency. The benefits of accounting for demand variation are further demonstrated through a simulation-based analysis using sampled weekly data.
The Land of Opportunity: Bioarchaeological Perspectives of Women’s Lives in the Industrial Expansion into the Western UNITED STATES (1850–1915)
Authors: P. Anderson Cheryl , P. Harrod Ryan , M. Baustian Kathryn 
Published: June 2024

AbstractTaking a bioarchaeological approach that puts human skeletal remains in context with historical records, we reconstruct the experiences of three women who lived in the West during the 1800s and early 1900s. Telling the stories of one woman from a homestead outside the city of Las Vegas, Nevada and two women recovered from a sand dune near Walters Ferry, Idaho, we offer insight into what life was like for those who ventured west in search of new identities and roles in developing industries. Our analysis includes documentation of pathological conditions, activity-related changes, and trauma in comparison to other historic cemetery samples from communities growing in this region. Through examination of the skeletal data from these diverse data sets, patterns emerge regarding the health profiles of these women. In particular, the results show that the pathological conditions observed on the three women from Nevada and Idaho align with those documented in the published literature and provide insight into their risk of morbidity and trauma.
Root participles: directive, commissive, expressive and representative participles in Germanic root configurations
Authors: Wegner Dennis 
Published: June 2024

AbstractThe present paper investigates participial root configurations, i.e. participial clauses that are grammatically independent of a host clause. Unlike previous work, which has focussed on either directive or (non-directive) performative uses of so-called past participles (i.e. participles that have passive and/or perfect(ive) interpretations), the present paper establishes a typology of ‘root participles’ in Germanic and contrasts the properties of four main types: (1) directive (RPdir), (2) expressive (RPexp), (3) commissive (RPcom), (4) representative root participles (RPrep). The main claim with respect to the properties of these distinct types is that they differ in terms of whether they include a verbal or an adjectival (passive) participle. In fact, arguments based on argument structure, orientation, aspect, and adverbial modification are presented to substantiate the claim that types (1) and (2) are formed with verbal and types (3) and (4) with adjectival participles. Additionally, the distinct types will be shown to differ in their status of either being non-sentential (i.e. structurally different from potential clausal counterparts) or merely elliptical (just phonologically reduced): types (1) and (3) can be shown to be non-sentential and hence receive a dedicated syntactic analysis, where special attention is paid to the contribution of the (imperative vs. declarative) left periphery.
Quantitatively measuring the cytotoxicity of viscous hydrogels with direct cell sampling in a micro scale format “MicroDrop” and its comparison to CCK8
Authors: Margot Anna Marie , Engels Andreas , Sittinger Michael , Dehne Tilo , Hemmati-Sadeghi Shabnam 
Published: June 2024

AbstractTissue engineering holds promise for developing therapeutic applications using viscous materials e.g. hydrogels. However, assessing the cytotoxicity of such materials with conventional assays can be challenging due to non-specific interactions. To address this, we optimized a live/dead staining method for quantitative evaluation and compared it with the conventional CCK8 assay. Our MicroDrop method involved seeding droplets containing 5000 cells in 10 µl medium on 12-well plates. After allowing them to adhere for 4 h, various viscous samples were applied to the cells and measurements were conducted using a fluorescence microscope immediately and at daily intervals up to 72 h. A sodium dodecyl sulfate (SDS) dilution series compared the MicroDrop with the CCK8 assay. The findings revealed a cell-type specific pattern for 10 mg/ml hyaluronic acid (HA), wherein MC3T3-E1 cells maintained 95% viability until 72 h, while L929 cells experienced a gradual decline to 17%. 2 mg/ml HA exhibited consistent viability above 90% across all time points and cell lines. Similarly, fibrin demonstrated 90% viability across dilutions and time points, except for undiluted samples showing a decrease from 85% to 20%. Gelatin-methacrylol sustained viability above 70% across all time points at both 5% and 10% concentrations. The comparison of the SDS dilution series between viability (MicroDrop) and metabolic activity (CCK8) assay showed a correlation coefficient of 0.95. The study validates the feasibility of the established assay, providing researchers with an efficient tool for assessing cytotoxicity in viscous materials. Additionally, it holds the potential to yield more precise data on well-known hydrogels.
Graphical Abstract
Biological and mechanical performance of calcium phosphate cements modified with phytic acid
Authors: Steinacker Valentin C. , Weichhold Jan , Renner Tobias , Gubik Sebastian , Vollmer Andreas , Breitenbücher Niko , Fuchs Andreas , Straub Anton , Hartmann Stefan , Kübler Alexander C. , Gbureck Uwe 
Published: June 2024

AbstractCalcium phosphate cements, primarily brushite cements, require the addition of setting retarders to ensure adequate processing time and processability. So far, citric acid has been the primary setting retarder used in this context. Due to the poor biocompatibility, it is crucial to explore alternative options for better processing. In recent years, the setting retarder phytic acid (IP6) has been increasingly investigated. This study investigates the biological behaviour of calcium phosphate cements with varying concentrations of IP6, in addition to their physical properties. Therefore cytocompatibility in vitro testing was performed using osteoblastic (MG-63) and osteoclastic (RAW 264.7 differentiated with RANKL) cells. We could demonstrate that the physical properties like the compressive strength of specimens formed with IP6 (brushite_IP6_5 = 11.2 MPa) were improved compared to the reference (brushite = 9.8 MPa). In osteoblast and osteoclast assays, IP6 exhibited significantly better cytocompatibility in terms of cell activity and cell number for brushite cements up to 11 times compared to the brushite reference. In contrast, the calcium-deficient hydroxyapatite (CDHA) cements produced similar results for IP6 (CDHA_IP6_0.25 = 27.0 MPa) when compared to their reference (CDHA = 21.2 MPa). Interestingly, lower doses of IP6 were found to be more effective than higher doses with up to 3 times higher. Additionally, IP6 significantly increased degradation in both passive and active resorption. For these reasons, IP6 is emerging as a strong new competitor to established setting retarders such as citric acid. These cements have potential applications in bone augmentation, the stabilisation of non-load bearing fractures (craniofacial), or the cementation of metal implants.
Graphical Abstract
Herbivory by Leaf-Cutting Ants: Exploring the Jasmonate Response in Host and Non-Host Plants
Authors: Müller Andrea Teresa , Ossetek Kilian Lucas , Mithöfer Axel 
Published: June 2024

AbstractLeaf-cutting ants (Formicidae; Atta spp., Acromyrmex spp.) cut off pieces of leaves and other plant tissue and feed it to their symbiotic fungi. As this foraging behavior poses an imminent threat to agriculture, leaf-cutting ants are considered as pests of huge ecologically and economically importance. Consequently, research on leaf-cutting ants focused on their foraging decisions and interactions with their cultivated symbiotic fungi, whereas their effect on the attacked plants, apart from the loss of plant tissue, remains largely unknown. In this study, we investigated the consequences of an attack by leaf-cutting ants and analyzed the plants’ defense responses in comparison to chewing caterpillars and mechanical damage. We found that an attack by leaf-cutting ants induces the production of jasmonates in several host and non-host plant species (Arabidopsis thaliana, Vicia faba, Phaseolus lunatus, Tococa quadrialata). Additionally, we showed in the natural host plant lima bean (P. lunatus) that leaf-cutting ant damage immediately leads to the emission of typical herbivory-induced plant volatiles, including green leaf volatiles and terpenoids. Further data exploration revealed clear differences in the defense-related phytohormone profile in plant species of Neotropical and Eurasian origin. Taken together, we show that leaf-cutting ant infestation and their way of clipping the plants’ tissues induce jasmonate and jasmonates-mediated responses and do not differ from those to mechanical injury or larval feeding.
The Impact of Sorbent Amendments for Mercury Remediation on the Viability of Soil Microorganisms
Authors: Ogbudu Jeffrey , Egbo Timothy E. , Johs Alexander , Sahu Rajnish , Abdelmageed Yazeed , Ayariga Joseph , Robertson Boakai K. 
Published: June 2024

AbstractMercury (Hg) remediation across contaminated environments in the United States is an ongoing project. As part of the Hg cleanup strategy at East Fork Poplar Creek (EFPC), located in Oak Ridge, TN, the deployment of sorbents is considered. However, the impact of sorbents on soil microorganisms is poorly understood. In this study, we investigated the effect of sorbents on soil microorganism viability and biofilm formation to assess soil health during sorbent application for Hg remediation. We specifically investigated the effect of two engineered sorbents, Organoclay PM-199 and Organoclay MRM (which are manufactured from clay minerals formulated for various remediation applications), on two gram-negative organisms (Serratia marcescens and Burkholderia thailandensis) isolated from the Hg-contaminated EFPC bank soil. Pure cultures of S. marcescens or B. thailandensis were amended with 5% (w/v) and 25% (w/v) PM-199 and MRM, respectively, for 9 days. The samples were harvested, and bacterial cell viability was determined using a BacLight staining kit. Results showed that the growth of sorbent-amended S. marcescens was inhibited in contrast to that of unamended control. Furthermore, biochemical assays were used to analyze bacterial biofilm formation and integral biofilm components. Our results suggest that biofilm formation by sorbent-amended S. marcescens was negatively affected. In contrast, B. thailandensis amended with low concentrations of MRM showed enhanced growth and notable differences in biofilm morphology. These results suggest that the use of organoclay PM-199 and MRM at higher concentrations in field studies may hinder the growth of specific soil microorganisms.
Microstructural Evolution of Tantalum During Deformation and Subsequent Annealing
Authors: Brown Donald W. , Anghel Veronica , Clausen Bjorn , Pokharel Reeju , Savage Daniel J. , Vogel Sven C. 
Published: June 2024

AbstractMicrostructure-aware models are necessary to predict the behavior of material based on process knowledge or to extrapolate mechanical properties of materials to environmental conditions which are not easily reproduced in the laboratory, e.g., nuclear reactor environments. Elemental Ta provides a relatively simple BCC system in which to develop a microstructural understanding of deformation processes which can then be applied to more complicated BCC alloys. In situ neutron diffraction during compressive deformation and subsequent heat treatment have been used to monitor the evolution of microstructural features in Ta throughout simulated processing steps. Crystallographic texture and dislocation density are determined as a function of first plastic strain, then temperature. Lattice strains are determined and attributed to stresses at macroscopic, grain and dislocation length scales. The increase of the dislocation density through deformation and subsequent recovery during heat treatment is monitored through the changing diffraction line profile. Also, randomization of the texture is used as a signature of recrystallization. The recovery of dislocations through annihilation is not observed to depend on the initial dislocation density in the range studied here. In contrast, recrystallization is observed to depend strongly on the initially dislocation density.
The Power to Exclude: The (Mis)Treatment of Unaccompanied Minors under the Trump and Biden Administration
Authors: Gerken Christina 
Published: June 2024

AbstractIn “The Biden Plan for Securing Our Values as a Nation of Immigrants” (hereinafter “Biden Plan“), then-candidate Joe Biden promised to “reassert America’s commitment to asylum-seekers and refugees.” Three years into his presidency, how far has the Biden Administration come in their efforts to create a more humane asylum system? And has the treatment of unaccompanied minors seen any significant improvements? This article examines the Trump Administration’s attempts to permanently alter the US asylum system. After trying to categorically ban all claims that were based on persecution by “private actors,” the Trump Administration seized on the COVID-19 pandemic as a convenient pretext for taking away even some of the most basic human rights protections that asylum-seekers have enjoyed for generations. This article will argue that the Biden Administration, despite their efforts to restore some basic protections, continues to criminalize and institutionalize many unaccompanied minors.
The acceptability of technology-enabled physical activity feedback in cardiac patients and health care professionals
Authors: Springett Daniella , Lauber Kathrin , Gillison Fiona , Wort Georgina , Augustine Daniel , Thompson Dylan , Peacock Oliver 
Published: June 2024

Abstract
Purpose
Physical activity is a key component of cardiac rehabilitation (CR). Despite the widely reported benefits of CR, uptake in the United Kingdom is still low. Alternative home-based and technology-facilitated delivery models are needed to improve CR uptake and physical activity. This study set out to explore patient and clinician views of personalised, multidimensional physical activity feedback and its potential use within CR.

Methods
We developed graphics for the presentation of personalised multidimensional physical activity feedback from data collected through wrist-worn monitors. Thirteen cardiac patients and nine healthcare professionals recruited from South West England wore research grade physical activity monitors for seven days. Participants then attended semi-structured interviews during which personalised physical activity feedback was provided. Interviews were audio-recorded, transcribed, and analysed thematically.

Results
Two main themes were derived from the data which covered: 1) the perceived value of multidimensional physical activity feedback, and 2) support needed to facilitate understanding. Within the first theme, participants acknowledged that multidimensional physical activity feedback was useful for monitoring progress, goal setting, and increasing self-awareness of physical activity behaviour among both patients and clinicians. Within theme two, the need for more guidance and support from clinicians to aid patient understanding and reassurance was highlighted, particularly for those with very low physical activity levels.

Conclusions
Multidimensional physical activity feedback delivered using a technology-enabled approach was perceived as acceptable among patients and clinicians. This study provides insights into the potential novel use of technology-enabled physical activity feedback to support and expand the delivery of CR.
Maclura tinctoria (L.) D. Don ex Steud. (Moraceae): a review of the advances in ethnobotanical knowledge, phytochemical composition, and pharmacological potential
Authors: Quintero-Rincón Patricia , Pájaro-González Yina , Diaz-Castillo Fredyc 
Published: June 2024

AbstractMaclura tinctoria (Moraceae), commonly known as dinde, is a lactescent tree of significant economic importance with extensive ethnomedicinal and ethnobotanical applications. Among native populations in the Neotropics, dinde is used to address diverse forms of inflammatory arthritis, along with ailments stemming from viral, bacterial, or fungal origins. Its efficacy stands out notably in the treatment of conditions affecting the buccal cavity, respiratory tract, and venereal infections. These medicinal attributes have spurred investigations into their potential for developing nutraceuticals and pharmacological agents. Also, dinde has a commercial appeal intertwined with the remarkable qualities of its wood, which include the resistance to moisture and termites. This review consolidates information encompassing peer-reviewed articles from major scientific databases such as Science Direct, Scopus, Springer, PubMed, and Google Scholar. The review spans fifty-four phytocompounds, characterized by remarkable structural complexity and identified from the year 2000 onward. These compounds are categorized into flavones, isoflavones, flavonols, flavanols, flavanones, chalcones, and xanthones, where a significant portion exhibiting glycosylation or prenylation. Additionally, phenolic acids and condensed tannins contribute to the chemical diversity of this species. This comprehensive review offers updated insights into the potential bioactivity of chemical constituents identified in this plant, elucidating findings derived from different studies employing both in vitro and in vivo assays.
Graphical abstract
Middle Devonian reef-derived calciturbidites of western Ossa-Morena Zone (Portugal): conodont biostratigraphy of the Eifelian Pedreira da Engenharia Limestone
Authors: Silvério Gonçalo , Liao Jau-Chyn , Valenzuela-Ríos José I. , Machado Gil , Barreto Pedro , Moreira Noel 
Published: June 2024

AbstractThe first biostratigraphical study on the complete Pedreira da Engenharia quarry section (Middle Devonian, SW Portugal) is presented. A total of 32 samples were collected from the three subsections (PE-A, quarry floor; PE-B and PE-C). This led to the identification of 15 species belonging to the genera Icriodus, Polygnathus and Tortodus. Four index species were identified: P. costatus; T. australis; T. kockelianus; and P. ensensis. The age for the Pedreira da Engenharia section was updated from the costatus zone (Boogaard, 1972) to the costatus-ensensis zones (lower to uppermost Eifelian). There is a thin part of the succession representing the kockelianus and, possibly, eiflius zones, together being represented by 1,5 m. A CAI value of 5-5.5 for the conodont elements indicates a maximum temperature of over 300 ºC. The Pedreira da Engenharia Limestone, together with the Odivelas Limestone, are evidence of the development of calciturbidite sedimentation associated with atoll-like structures (only preserved in Odivelas) along the SW boundary of Ossa-Morena Zone, being probably associated with the beginning of the subduction of the Rheic Ocean during Early to Middle Devonian times.
Biochar technology cannot offset land carbon emissions in Guangdong province, China
Authors: Wang Funing , Zhou Wenneng , Wang Xili , Zhao Qing , Han Mengjie 
Published: June 2024

AbstractAs a highly developed region, Guangdong province has substantial industrial emissions. Its subtropical monsoon climate, characterized by abundant hydrothermal conditions, contributes to a substantial biomass potential. The adoption of potential biomass-based carbon dioxide removal (CDR) technologies, such as biochar, presents an opportunity to mitigate emissions and work towards carbon neutrality in the future. However, the current state of the land carbon balance and the CDR potential of biochar in Guangdong province remains unclear. We first calculated the land carbon balance based on inventory data. Then we estimated the CDR potential of biochar derived from agricultural residues, forestry residues, and bioenergy crops cultivated on marginal lands in Guangdong province using life cycle analysis (LCA). Results show that Guangdong province has not yet achieved carbon neutrality, with a net emission (carbon emissions remaining after offsetting by carbon sinks) of 925.63 Tg CO2e (CO2 equivalent, 1Tg = 106 t) in 2021. Emissions from energy consumption account for the highest proportion, contributing 83.8% of total emissions. In the highest biomass utilization scenario, the maximum CDR potential of biochar derived from all biomass types reaches 84.30 Tg CO2e yr-1, which could offset 9.11% of net carbon emissions in Guangdong province. Our findings provide crucial guidance for setting emission reduction targets and implementing effective mitigation strategies in Guangdong province under temperature warming.
Graphical Abstract