bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi‐center study on sellar reconstruction after endoscopic transsphenoidal pituitary surgery
Authors: Ali Hawa M. , Leland Evelyn M. , Stickney Emily , Lohse Christine M. , Iyoha Ehiremen , Valappil Benita , Filimonov Andrey , Goetschel Kaitlin , Young Sarah C. , Shahin Maryam N. , Sanusi Olabisi , Sonfack Davaine Joel Ndongo , Nadeau Sylvie , Champagne Pierre‐Olivier , Geltzeiler Mathew , Zwagerman Nathan T. , Gardner Paul A. , Wang Eric W. , Zenonos Georgios A. , Snyderman Carl , Van Gompel Jamie , Link Michael , Peris‐Celda Maria , Stokken Janalee , Choby Garret , Pinheiro‐Neto Carlos D. 
Published: June 2024

AbstractIntroductionSurgical techniques for sellar reconstruction include no reconstruction, use of synthetic materials, autologous grafts, and/or vascularized flaps. The aim of this study was to conduct a multi‐center study comparing the efficacy and postoperative morbidity associated with different sellar reconstruction techniques.MethodsA retrospective chart review of patients who underwent endoscopic transsphenoidal surgery for pituitary tumors from five participating sites between January 2021 and March 2023 was performed. The variables included demographics, tumor characteristics, reconstruction technique, postoperative cerebrospinal fluid leak (CSF) leak, and 22‐item Sino‐Nasal Outcome Test (SNOT‐22) scores. Comparisons of postoperative complications, SNOT‐22 scores, and duration of surgery by type of onlay reconstruction were evaluated using Fisher's exact test, analysis of variance, and Kruskal‒Wallis test.ResultsFive hundred and one patients were identified. The median tumor size was 2.1 cm, and 64% were non‐functioning. Intraoperative CSF leak was identified in 38% of patients. A total of 89% of patients underwent onlay reconstruction: 49% were reconstructed with mucosal grafts, 35% with nasoseptal flaps, and 5% with other onlay techniques. Nasoseptal flaps were utilized more frequently in the setting of giant pituitary adenomas (>3 cm), medial cavernous sinus wall resection, and high‐flow intraoperative CSF leaks. Cases who utilized mucosal grafts had an overall shorter operating time (median: 183 min vs. 240 min; p < 0.001). Five postoperative CSF leaks were identified, and therefore, statistical analysis could not be performed for this complication.ConclusionThe effectiveness and morbidity of different sellar reconstruction techniques are comparable. Vascularized flaps were utilized more frequently in the setting of larger tumors and high‐flow intraoperative CSF leaks.
Advancements in the Use of Artificial Saturable Absorbers for Modelocking of 2 µm Ultrafast Fiber Lasers
Authors: Raj R Akshay , Saha Saikat , Mondal Shyamal 
Published: June 2024

AbstractOver the past decade, the research on modelocked 2 fiber lasers has increased rapidly. Conventionally, modelocking is achieved with the existing quantum well structures as well as 2D materials classified as Real Saturable Absorbers. As time progressed and keeping in mind the versatility, stability and robustness, demonstration of 2 fiber lasers that are modelocked by Artificial Saturable Absorbers (ASA) gained importance. This class of Saturable Absorbers exhibits interesting properties, which can make them the best candidate to replace real material‐based Saturable Absorbers. The progress of ASA based modelocking schemes in the 2 regime is explored and discussed in detail, along with its underlying physics, citing the various uses and the increasing market for ultrafast fiber lasers. Toward the end of this review, a comparison is drawn between different ASAs based modelocking schemes to get the most favorable conditions for desired output parameters as per one's needs. These fiber lasers with an all‐fiber ASA foundation have potential uses in the fields of medical, LIDAR, mid‐IR generation, environmental sensing, industrial, and defence.
Altering the CO2 Electroreduction Pathways Towards C1 or C2+ Products via Engineering the Strength of Interfacial Cu−O Bond
Authors: Zhang Yu , Li Yicheng , Gao Nana , Delmo Ernest Pahuyo , Hou Guoyu , Luo Ali , Wang Dongyang , Chen Ke , Antonietti Markus , Liu Tianxi , Tian Zhihong 
Published: June 2024

AbstractCopper (Cu)‐based catalysts have established their unique capability for yielding wide value‐added products from CO2. Herein, we demonstrate that the pathways of the electrocatalytic CO2 reduction reaction (CO2RR) can be rationally altered toward C1 or C2+ products by simply optimizing the coordination of Cu with O‐containing organic species (squaric acid (H2C4O4) and cyclohexanehexaone (C6O6)). It is revealed that the strength of Cu−O bonds can significantly affect the morphologies and electronic structures of derived Cu catalysts, resulting in the distinct behaviors during CO2RR. Specifically, the C6O6−Cu catalysts made up from organized nanodomains shows a dominant C1 pathway with a total Faradaic efficiency (FE) of 63.7 % at −0.6 V (versus reversible hydrogen electrode, RHE). In comparison, the C4O4−Cu with an about perfect crystalline structure results in uniformly dispersed Cu‐atoms, showing a notable FE of 65.8 % for C2+ products with enhanced capability of C−C coupling. The latter system also shows stable operation over at least 10 h with a high current density of 205.1 mA cm−2 at −1.0 VRHE, i.e., is already at the boarder of practical relevance. This study sheds light on the rational design of Cu‐based catalysts for directing the CO2RR reaction pathway.
A General Strategy Based on Hetero‐Charge Coupling Effect for Constructing Single‐Atom Sites
Authors: Peng Cheng , Wang Mingyue , Li Sha , Zeng Xuezhi , Wang Jieyue , Wang Wenhai , Zhang Zhirong , Ye Mingfu , Wei Xianwen , Wu Konglin , Zhang Kui , Zeng Jie 
Published: June 2024

AbstractSingle‐atom catalysts have emerged as cutting‐edge hotspots in the field of material science owing to their excellent catalytic performance brought about by well‐defined metal single‐atom sites (M SASs). However, huge challenges still lie in achieving the rational design and precise synthesis of M SASs. Herein, we report a novel synthesis strategy based on the hetero‐charge coupling effect (HCCE) to prepare M SASs loaded on N and S co‐doped porous carbon (M1/NSC). The proposed strategy was widely applied to prepare 17 types of M1/NSC composed of single or multi‐metal with the integrated regulation of the coordination environment and electronic structure, exhibiting good universality and flexible adjustability. Furthermore, this strategy provided a low‐cost method of efficiently synthesizing M1/NSC with high yields, that can produce more than 50 g catalyst at one time, which is key to large‐scale production. Among various as‐prepared unary M1/NSC (M can be Fe, Co, Ni, V, Cr, Mn, Mo, Pd, W, Re, Ir, Pt, or Bi) catalysts, Fe1/NSC delivered excellent performance for electrocatalytic nitrate reduction to NH3 with high NH3 Faradaic efficiency of 86.6 % and high NH3 yield rate of 1.50 mg h−1 mgcat.−1 at −0.6 V vs. RHE. Even using Fe1/NSC as a cathode in a Zn‐nitrate battery, it exhibited a high open circuit voltage of 1.756 V and high energy density of 4.42 mW cm−2 with good cycling stability.
Ion Exchange‐Mediated 3D Cross‐Linked ZIF‐L Superstructure for Flexible Electrochemical Energy Storage
Authors: Ding Hongye , Liu Zheng , Xie Ju , Shen Zizhou , Yu Dianheng , Chen Yihao , Lu Yibo , Zhou Huijie , Zhang Guangxun , Pang Huan 
Published: June 2024

AbstractMetal–organic frameworks (MOFs) are considered as a promising candidate for advancing energy storage owing to their intrinsic multi‐channel architecture, high theoretical capacity, and precise adjustability. However, the low conductivity and poor structural stability lead to unsatisfactory rate and cycling performance, greatly hindering their practical application. Herein, we propose a sea urchin‐like Co‐ZIF‐L superstructure using molecular template to induce self‐assembly followed by ion exchange method, which shows improved conductivity, successive channels, and high stability. The ion exchange can gradually etch the superstructure, leading to the reconstruction of Co‐ZIF‐L with three‐dimensional (3D) cross‐linked ultrathin porous nanosheets. Moreover, the precise control of Co to Ni ratios can construct effective micro‐electric field and synergistically enhance the rapid transfer of electrons and electrolyte ions, improving the conductivity and stability of CoNi‐ZIF‐L. The Co6.53Ni‐ZIF‐L electrode exhibits a high specific capacity (602 F g−1 at 1 A g−1) and long cycling stability (95.3 % retention after 4,000 cycles at 5 A g−1). The Co6.53Ni‐ZIF‐L//AC asymmetric flexible supercapacitor employing gel electrolyte also exhibits excellent cycling stability (93.3 % retention after 4000 cycles at 5 A g−1). This discovery provides valuable insights for electrode material selection and energy storage efficiency improvement.
Polymeric Prodrugs using Dynamic Covalent Chemistry for Prolonged Local Anesthesia
Authors: Xue Tianrui , Li Yang , Torre Matthew , Shao Rachelle , Han Yiyuan , Chen Shuanglong , Lee Daniel , Kohane Daniel S. 
Published: June 2024

AbstractDepot‐type drug delivery systems are designed to deliver drugs at an effective rate over an extended period. Minimizing initial “burst” can also be important, especially with drugs causing systemic toxicity. Both goals are challenging with small hydrophilic molecules. The delivery of molecules such as the ultrapotent local anesthetic tetrodotoxin (TTX) exemplifies both challenges. Toxicity can be mitigated by conjugating TTX to polymers with ester bonds, but the slow ester hydrolysis can result in subtherapeutic TTX release. Here, we developed a prodrug strategy, based on dynamic covalent chemistry utilizing a reversible reaction between the diol TTX and phenylboronic acids. These polymeric prodrugs exhibited TTX encapsulation efficiencies exceeding 90 % and the resulting polymeric nanoparticles showed a range of TTX release rates. In vivo injection of the TTX polymeric prodrugs at the sciatic nerve reduced TTX systemic toxicity and produced nerve block lasting 9.7±2.0 h, in comparison to 1.6±0.6 h from free TTX. This approach could also be used to co‐deliver the diol dexamethasone, which prolonged nerve block to 21.8±5.1 h. This work emphasized the usefulness of dynamic covalent chemistry for depot‐type drug delivery systems with slow and effective drug release kinetics.
Supramolecular Complex of Cucurbit[7]uril with Diketopyrrolopyrole Dye: Fluorescence Boost, Biolabeling and Optical Microscopy
Authors: Kim Dojin , Bossi Mariano L. , Belov Vladimir N. , Hell Stefan W. 
Published: June 2024

AbstractNew photostable and bright supramolecular complexes based on cucurbit[7]uril (CB7) host and diketopyrrolopyrole (DPP) guest dyes having two positively charged 4‐(trimethylammonio)phenyl groups were prepared and characterized. The dye core displays large Stokes shift (in H2O, abs./emission max. 480/550 nm; ϵ~19 000, τfl>4 ns), strong binding with the host (~560 nM Kd) and a linker affording fluorescence detection of bioconjugates with antibody and nanobody. Combination of protein‐functionalized DPP dye with CB7 improves photostability and affords up to 12‐fold emission gain. Two‐color confocal and stimulated emission depletion (STED) microscopy with 595 nm or 655 nm STED depletion lasers shows that the presence of CB7 not only leads to improved brightness and image quality, but also results in DPP becoming cell‐permeable.
Aerogel‐like biodegradable acoustic foams of bacterial cellulose
Authors: Mehrotra Nitisha , Bhuvana Thiruvelu , Tiwari Anjali , Chandraprakash C. 
Published: June 2024

AbstractWe report the first work on the development of biodegradable acoustic foams from self‐grown bacterial cellulose (BC) from kombucha solution and green processing techniques. Kombucha BC‐agar and kombucha BC‐polyvinyl alcohol foams were fabricated by using slurries of BC pellicles mixed with the additives, froze for 24 h, and recast into foams using the freeze‐drying method. The foams were aerogel‐like with a density 20 kg/m3, thermally stable upto 220 °C, and crystallinity ~74%. Morphological analysis revealed macropores with coarse walls in agar‐based foams, whereas the PVA‐based foams comprised a polydisperse pore network with coarse walls. A broadband absorption was observed with a maximum of 0.4 for the 2.5‐mm‐thick single‐layer foams and 0.9 for the 12‐mm‐thick multilayer foams. The sound absorption was found to be on par with the biodegradable foams of agar and other cellulose‐rich materials such as agricultural residue, yet with a lightweight. Being largely porous, the foams had little transmission loss. As the densities and the crystallinities of these foams are tunable by the addition of other polymers, the results from this study provide scope to explore BC‐based lightweight materials for large‐scale fabrication suitable for sound absorption over specific regimes.
Labour market institutions for immigrants: The case of high‐wage migrant workers in Indonesia
Authors: Palmer Wayne 
Published: June 2024

AbstractThis paper presents a novel ‘legal process’ analysis to examine labour market institutions' role in addressing violations of migrants' labour rights in Indonesia. Examining 92 labour disputes and conducting qualitative interviews with stakeholders, the study explores Indonesia's primary labour market institutions' effectiveness in safeguarding migrants' rights. Systemic shortcomings within Indonesia's labour market institutions are revealed, indicating their limited capacity to protect migrants' labour rights effectively. Qualitative interviews provide insights into various foci and disconnects contributing to institutional failures. Calling attention to the role of the state, this study identifies ‘institutional fixes’ that facilitate migrant rights protection, such as the assistance provided by private lawyers. It argues for shifting focus from ‘migrant exceptionalism’ to acknowledging migrants' experiences within labour market institutions as workers. This study contributes to understanding migrant labour governance in Indonesia, emphasizing the need to address institutional failures and advocate for comprehensive reforms to protect migrants' rights effectively.
Fabrication of Porous Adsorbents Templated from Capillary Foam Stabilized with Chlorella for Highly Efficient Removal of Cationic Dyes
Authors: Yu Hui , Zhu Yongfeng , Duan Fangzhi , Hui Aiping , Wang Aiqin 
Published: June 2024

AbstractThe thermodynamic instability of conventional aqueous foam‐stabilized surfactants is a critical bottleneck in the construction of porous materials. Herein, a novel strategy is proposed for preparing a capillary foam based on Chlorella and utilizing it as a template for constructing porous materials with high‐efficiency adsorption. The capillary foam was stabilized by Chlorella particles enclosed within a gel network of oil bridges connecting the particles (capillary suspension). Chlorella particles, which act as stable particles, form oil bridges and are distributed at the phase interface of the capillary foam. These particles exhibited resistance to shear forces, allowing the formation of a long‐term stable capillary foam. Using this foam as a template, a porous material with outstanding adsorption performance for Methylene Blue (MB) and Brilliant Green (BG) dyes was successfully constructed. Additionally, the material exhibited a sustained high adsorption performance even after five thermal regeneration‐adsorption cycles. In conclusion, this study presents a green and straightforward method for constructing capillary foams with high stability, which is a promising approach for developing porous materials with exceptional adsorption and regeneration properties for dyes.
A robust network binder enables high‐performance silicon anode via localized linking by small molecules
Authors: Chen Junyi , Han Lin , Zhang Wu , Wan Guangying , Zhang Zhen , Tao Xinyong , Liu Tiefeng 
Published: June 2024

AbstractThe importance of network binder for improving cycling lifespan of silicon (Si) anode needs no further emphasis. However, the linear structure of natural polymer hardly creates a robust network binder. Herein, we propose a facile strategy of establishing a robust network binder by using small molecules of tartaric acid (TA) to locally link sodium carboxymethyl cellulose (CMC). Through hydrogen or covalent bonds, the resultant CMC‐TA binder exhibits improved tensile and adhesive properties. The Si anode using CMC‐TA binder delivers a satisfactory specific capacity of 2213 mAh g−1 after 100 cycles at the rate of 0.2 C, with a capacity retention rate of 68.8%. This result has well confirmed the effectiveness of using small molecules to reinforce hydrogen‐bonding linking between CMC and between Si particles for a high‐performance Si anode.
TRIM8 promotes ovarian cancer proliferation and migration by targeting VDAC2 for ubiquitination and degradation
Authors: Wu Fei , Xu Jiaqi , Jin Xin , Zhu Yue , Gao Wenxin , Liu Meng , Zhang Yan , Qian Weifeng , Huang Xiaoyan , Zhao Dan , Feng Guannan , Hou Shunyu , Xi Xiaoxue 
Published: June 2024

AbstractBackgroundOvarian cancer is a common gynecological tumor with high malignant potential and poor prognosis. TRIM8, is involved in the development of various tumors, but its precise regulatory role in ovarian cancer is still unknown.AimsThe aim of this study was to explore the specific mechanism by which TRIM8 regulates ovarian cancer.Materials and MethodsWe used bioinformatics analysis to screen for high expression of TRIM8 in ovarian cancer. The expression of TRIM8 in healthy and cancerous ovarian tissues was assessed by immunofluorescence. TRIM8 was silenced or overexpressed in ovarian cancer cell lines, with cell proliferation and migration evaluated by CCK8, transwell and clonal formation assays. The effect of TRIM8 on ovarian cancer cells in vivo was assessed by subcutaneous tumor formation experiments in nude mice. The potential interacting protein VDAC2 was identified by mass spectrometry. The mechanism underlying TRIM8 regulation of VDAC2 was evaluated by co‐immunoprecipitation and western blotting.ResultsTRIM8 was overexpressed in ovarian cancer. TRIM8 promoted the proliferation and migration of ovarian cancer cells in vitro and the growth of subcutaneous tumors in mice in vivo. TRIM8 interacted with VDAC2, weakened the stability of the protein, and promoted its polyubiquitination and subsequent degradation. Knockdown of VDAC2 increased the resistance of ovarian cancer cells to iron death, whereas overexpression of VDAC2 attenuated ovarian cancer progression induced by TRIM8 overexpression.DiscussionTRIM8 promotes ovarian cancer proliferation and migration by targeting VDAC2 for ubiquitination and degradation, these finding may provide new targets for the treatment of ovarian cancer.ConclusionTRIM8 degraded VDAC2 through the ubiquitination pathway, increased the resistance of ovarian cancer cells to iron death, and promoted the proliferation and migration of ovarian cancer.
Squirrel bite—a rare cause of necrotizing soft tissue infection: Case report
Authors: Adjei Prosper , Bosomtwi Boateng , Asamoah Prince Henry , Asasu Stanley Anenyemele , Ohene Dominic Asante , Amoakohene‐Yeboah Augustina , Abban Kojo Eduakwa 
Published: June 2024

Key Clinical MessageAlthough squirrel bites are uncommon and generally benign, they have been implicated in the transmission of certain diseases in humans, some of which can be life‐threatening. This report discusses the case of a 27‐year‐old hunter who developed a necrotizing soft tissue infection with vesiculo‐bullous skin lesions after a ground squirrel bite.
Sleep disruptions and the pathway to psychosis: An in‐depth case and literature review
Authors: Kim Jeffrey , Prasad Sakshi , Roshan Nikhita Suzanne , Hasan Bushra Farah , Gill Gurtej , Gunturu Sasidhar 
Published: June 2024

Key Clinical MessageThe case highlights an unusual presentation where sleep issues preceded psychotic symptoms, implying link between disrupted sleep and psychosis onset. Earlier symptoms were viewed as depression but may have signaled psychosis exacerbated by insomnia.AbstractSleep disorders, prevalent yet frequently overlooked in individuals with psychotic disorders, have significant associations with the onset and severity of psychosis. Here we describe the case of a patient who first presented with insomnia, but whose condition improved with the use of risperidone and was diagnosed with first‐episode psychosis. Multiple studies emphasize the critical relationship between sleep disturbances and psychosis, particularly in the lead‐up to first‐episode psychosis. Structural abnormalities in the brain, notably the thalamus, combined with neurotransmitter imbalances involving dopamine and acetylcholine, seem pivotal in this interrelation. The connection between dopamine, sleep disturbances, and psychosis, specifically the role of D2 dopamine receptors, highlights a potential pathway bridging sleep irregularities with psychosis. The study underscores the need for further research to delineate the relationship between sleep disturbances and psychosis and to assess the efficacy of various therapeutic interventions targeting both conditions.
A Perspective on Photocatalytic Synthesis of NH3, Urea, and Amino Acids by Nanomaterials: Progress and Prospects
Authors: Bhattacharyya Biswajit , Sarhan Radwan M. , Lu Yan , Taubert Andreas 
Published: June 2024

AbstractA sustainable world is only possible when we are ready to deliver a net zero carbon emission energy sector. In this regard, we must not only consider more renewable energy resources but also find alternate paths for making some popular molecules like NH3 and urea for a lesser carbon footprint. This perspective article summarizes the recent progress of the photocatalytic synthesis of NH3, urea, and some amino acids using novel nanomaterials where we have focused on various approaches to catalyst design like metal oxides, metal sulfides, metal‐free catalysts, and biomimicking catalysts for ambient condition N2 activation. Later we discussed general reaction pathways, a detailed mechanistic overview, and future material layout for a sustainable approach towards N2 activation.
Photoelectrocatalytic Water Splitting by Conformal Copper‐Oxide on Hematite Nanostructures: Dependence on Surface‐States
Authors: Benkó Tímea , Shen Shaohua , Németh Miklós , Lukács Dávid , Xu Yufei , Khan Irfan , Czigány Zsolt , Endre Horváth Zsolt , Kovács Zoltán , Su Jinzhan , Sándor Pap József 
Published: June 2024

AbstractUnderstanding the pivotal role of surface co‐catalysts is paramount in the strategic design of forthcoming photoelectrodes. However, the nuanced impacts of co‐catalysts remain elusive, particularly in promoting the water oxidation reaction on hematite, especially in connection to surface states denoted as S1 (higher energy) and S2 (lower energy). For this purpose, we tailored two isomorphous hematite nanoarrays with a thin layer of amorphous copper oxide (CuOx), composed of a blend of Cu(I) and Cu(II) species, via a soft electrodeposition technique. Remarkably, we discovered that in pristine hematite (α‐Fe2O3), the S2 state played a pivotal role in activating the CuOx ad‐layer for water oxidation. At lower external biases (approximately 0.9–1.1 VRHE), CuOx served as charge reservoir in equilibrium with the S2 state. Notably, beyond 1.1 VRHE, where the high‐energy holes of the S1 state became available, CuOx was activated indirectly through the equilibrium with the S2 state, and a pronounced enhancement in photocurrent was observed. Conversely, in the case of Ti‐doped hematite (Ti : α‐Fe2O3) devoid of the S2 state, the presence of CuOx resulted in a decline in charge transfer efficiency. Instead of facilitating water oxidation, CuOx adversely affected the S1 surface sites and reduced the charge carrier density in Ti : α‐Fe2O3.