bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die antioxidative Wirkung von Produkten der Maillard‐Reaktion in Modellsystemen und gerösteten Haselnüssen
Authors: Nienaber U. , Eichner K. 
Published: October 2010

AbstractLösungen von Glucose und verschiedenen Aminosäuren wurden in Phosphatpuffer pH 7.0 erhitzt. Bräunung und Reduktionskraft dieser Maillard‐Reaktionslösungen zeigten Korrelation und stiegen in der Reihenfolge saure — neutrale — basische Aminosäuren an. Bei Zusatz zu wäßrigen Emulsionen von Linolsäuremethylester (LSME) stieg die antioxidative Wirkung in der Reihenfolge basische — saure — neutrale Aminosäuren an. Die entsprechenden Aminosäuren allein zeigten keinen, verschiedene Amadori‐Verbindungen (Fructose‐Alanin, ‐Arginin und ‐Histidin) dagegen einen prooxidativen Effekt. Auch in Extrakten aus gerösteten. entfetteten Haselnüssen ergab sich eine Korrelation zwischen Bräunung und Reduktionskraft. Wäßrige Extrakte besaßen höhere Bräunung und Reduktionskraft als entsprechende Methanol‐Extrakte; die antioxidative Wirkung beider Extrakte in LSME‐Emulsioncn war jedoch vergleichbar und stieg sowohl mit der Röstdauer als auch mit der zugesetzten Extraktmenge an. Die Extrakte wurden mittels Gelpermeationschromatographie an Sephadex G‐15 in drei Haupt‐fraktionen aufgetrennt. Eine antioxidative Wirkung wurde hauptsächlieh in der Fraktion der niedermolckularen farblosen Maillard‐Reakti‐onsprodukte gefunden.
Simultaneous Determination of Retinol Esters and Tocochromanols in Foods Using Nitro‐Column HPLC
Authors: Balz Marion , Schulte E. , Thier H.‐P 
Published: October 2010

AbstractAll food components with vitamin A and E activity, i.e. all‐trans retinol. its cis isomers and their esters as well as the four tocopherols. the four tocotrienols, and α‐tocopheryl acetate, were separated by HPLC using a nitro‐column and a three‐step gradient elution with n‐hexane and terα‐butylmethylether mixtures. β‐carotene and the retinol isomers were determined with an UV/Vis detector, all other compounds with a fluorescence detector connected in series. Fats, oils, and lipid extracts from foods can he injected onto the HPLC column without any clean‐up.
Vernolic and Cyclopropenoic Fatty Acids in Piper nigrum Seed Oil
Authors: Daulatabad C. D. , Mulla G. M. , Mirajkar A. M. 
Published: October 2010

AbstractThe seed oil of Piper nigrum has the following fatty acid composition: capric (4.1%), lauric (2.5%), myristic (3.1%), palmitic (27.2%), stearic (7.3%), oleic (29.9%), linoleie (7.7%), vernolie (7.7%), malvalie (6.3%), and sterculic (4.2%) acids.
Antioxidative Wirkung von Pflanzenextrakten auf Futterfette
Authors: Budinčević Mirjana , Verbaški Ž. , Turkulov J. , Dimić Etelka 
Published: October 2010

AbstractDie antioxidative Wirkung von cthanolischen Extrakten aus Maclura‐Früchten (Madura aurantiaca Nutt./Osage orange) sowie aus oberirdischen Pflanzenteilen von Asclepias synaca L. (Probe A). Che‐nopodium ambrosiodes L. (Probe B) und Thymus marschallianus Willd. (Probe C) wurde untersuchl. Als Substrate dienten Talg und Schweine‐schmalz (vorbcreitet durch NaBverfahren) bei 60° C. Die Versuche mit dem Rancimat‐Gerät wurden bei 100° C durchgeführt. Zum Vergleich wurde BHA als synthetisches Antioxidans eingesetzt. Die Pflanzenex‐trakte aus den Probcn A. B, C zeigten nur einc mittelmäßige antioxidative Wirkung bei den bei 60OC tempcrierten Substraten. Dies konnte aber durch die mit dem Rancimat erhaltenen Ergebnisse nicht besta‐tigt werden. Der Extrakt aus unreifen Maclura‐Früchten wies eine starke antioxidative Wirkung auf, die mit der von reinem BHA vergli‐chen werden kann und die Induktionsperiode der benutzten Substrate deutlich verlängerte. Die Zugabe von Zitronen‐ und Apfelsäure verur‐sachte einen synergistisehen Effekt. Weiterhin wurden Versuche mit dem Pulver aus unreifen Maclura‐Früchten durchgeführt. Die Zugabe von 0.1 — 0.2 % des Pulvers vcrursacht bei den Substraten Talg und Schwcineschmalz bei 60OC eine deutliche Verlängerung der Induktionsperiode. Annähernd wie bei Zusatz von 0.01 % BHA.
prüfung von Leinfuttermitteln (Saat, Extraktionsschrot) an wachsenden Schweinen – Futterwert, Thiocyanat‐und Schilddrüsenhormonstatus
Authors: Schöne Friedrich , Kirchheim Ulrich , Tischendorf Frank , Rudolph Berd 
Published: October 2010

AbstractLeinsamenschrot (Linum usitatissimum) wurde im Verdauungsversuch an 9 Mastschweinen im Austausch gegen Gerste geprüft. Die dreiTiere in jeder der drei Gruppen erhielten über drei Versuchsperioden im Lateinischen Quadrat Fuller ohne Lein oder mit 25% oder 50% Leinsamenschrot. In zwei Fütterungsvcrsuchen mit insgesamt 120 Absetzferkeln kamen Alleinfuttermischungen zum einen ohne und mit 10% Leinsamenschrot, zum anderen ohne und mit 10% Leinextraktionsschrot zum Einsatz. Die scheinbare Verdaulichkeit der organischen Substanz des Leinsamenschrotes erwies sich mit 66% als sehr niedrig. Mit 40% scheinbarer Verdaulichkeit trugen am meisten die Rohkohlenhydrate (Rohfaser + N‐freier Extrakt) zur Futterwertminderung bei. In den Leingruppen wurde viel Lignin im Futter aufgenommen und im Kot wiedergefunden. Das unverdauliche Lignin ist damil eine, wenn auch nicht die einzige, Ursache der Verdaulichkeitsminderung. Die trotzdem relativ hohe Energiedichte des Leinsamenschrotes von 18 MJ umsetzbarer Energie/kg Trockensubstanz (T) beruht auf seinem hohen Fettgehalt (40% der T). Mit Leinsamenschrot gefütterte Ferkel tendierten zu erhöhter Futteraufnahme sowie Gewichtszunahme und niedrigerem Futteraufwand. Die Futterration mit 10% Leinextraktionsschrot wurde tendenziell in geringerem Umfang aufgenommen, und die Körpermassezunahme erwies sich als geringer als dies in der Gruppe ohne Leinextiaktions‐schrot der Fall war. Im Blutserum zeigte sich nach Leinfuttermittelgabe eine drastisch erhöhte Thiocyanatkonzentration. Im Organismus wird Cyanid freigesetzt und mittels Schwefeltransferasen zum Thiocyanat entgiftet. Thiocyanat beeinträchtigl die Funktion der Schilddrüse, jedoch nur bei Iodmangel. Bei dem hohen Iodzusatz von 0,5mg/kg Futter unterschied sich zwischen den ohne oder mit Leinsamenschrot gefütterten Ferkeln die Konzentration des Blutserums an Thyroxin und Triiodthyronin nicht. Eine niedrigere Serum‐Thyroxin‐Konzentration der Leinextraktionsschrot‐gefütterten Ferkel wird auf andere Ursachen als auf die Iodgabe (0,5 mg/kg Futter) zurückgeführt.
Study on tribological properties of Al2O3 ceramics/1Cr18Ni9Ti stainless steel rubbing pairs in H2O2 solutions
Authors: Dong Conglin , Yuan Chengqing , Li Jun , Li Jian , Yan Xinping 
Published: October 2010

AbstractThe tribological properties of (Al2O3) ceramics/1Cr18Ni9Ti stainless steel rubbing pairs were investigated using a MMW‐1 tribo‐tester under pure water and different concentrations of hydrogen peroxide (H2O2) solutions. A comparison analysis of the friction coefficient, wear mass loss and worn surface topographies was conducted. The wear mass loss of the 1Cr18Ni9Ti stainless steel ring sample in all H2O2 solutions was greater than that in pure water. The wear mass loss was the highest in 70% H2O2 solution. The comprehensive analysis showed that the main wear mechanisms between the Al2O3 ceramics/1Cr18Ni9Ti stainless steel rubbing pairs were severe adhesive, abrasive and ploughing wear in the H2O2 solutions. It is believed that the knowledge gained in this study will provide the theoretical data and guide for the optimisation of the rubbing pairs in the H2O2 solutions to be used for the lubrication of some moving parts in the propulsion system of the launch vehicle. Copyright © 2010 John Wiley & Sons, Ltd.
Retransplantation for donor-derived neuroendocrine tumor
Authors: Begum Rehana , Harnois Denise , Satyanarayana Raj , Krishna Murli , Halling Kevin C. , Kim George P. , Nguyen Justin H. , Keaveny Andrew P. 
Published: October 2010

Abstract

Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor-derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases. The high grade nature of the NET was the most important determinant of prognosis in this case. Our experience suggests that retransplantation for donor-derived NET should only be considered when tumor biology is favorable. Liver Transpl 17:83-87, 2011. © 2011 AASLD.
Metabolic syndrome in liver transplant recipients
Authors: Laish Ido , Braun Marius , Mor Eytan , Sulkes Jaqueline , Harif Yael , Ari Ziv Ben 
Published: October 2010

Abstract

Features of metabolic syndrome are not uncommon in patients after liver transplantation. To examine the prevalence and risk factors of posttransplantation metabolic syndrome (PTMS), the files of 252 transplant recipients (mean age, 54.5 ± 2.8 years, 57.9% male) were reviewed for pretransplant and posttransplant clinical and laboratory parameters (mean follow-up, 6.2 ± 4.4 years). Rates of obesity (body mass index >30 kg/m2), hypertriglyceridemia (>150 mg/dL), high-density lipoprotein cholesterol <40 mg/dL (men) or <50 mg/dL (women), hypertension, and diabetes were significantly higher after transplantation than before. Metabolic syndrome was diagnosed in 5.4% of patients before transplantation and 51.9% after. Besides significantly higher rates of the typical metabolic derangements (P < 0.0001), the patients with PTMS were older and heavier than those without PTMS, and they had a higher rate of pretransplant hepatitis C virus infection (P < 0.03) and more posttransplant major vascular and cardiac events (20 events in 15.2% of patients with PTMS versus 6 events in 4.9% of patients without PTMS; P < 0.007). There was no between-group difference in mortality or causes of death (mainly related to recurrent disease, graft failure, and sepsis). Significant independent predictors of PTMS on logistic regression analysis were age (odds ratio [OR] = 1.04), pretransplant nonalcoholic fatty liver disease (OR = 3.4), body mass index (OR = 1.13), diabetes (OR = 5.95), and triglycerides (OR = 1.01). The rate of metabolic syndrome in liver transplant recipients is more than twice that reported for the general population. PTMS is associated with cardiovascular morbidity but not mortality, and it may be predicted by pretransplantation conditions. Prospective studies are required to determine the significance and management of PTMS. Liver Transpl 17:15-22, 2011. © 2011 AASLD.
Amphiphilic Cationic [Dendritic poly(L‐lysine)]‐block‐poly(L‐lactide)‐block‐[dendritic poly(L‐lysine)]s in Aqueous Solution: Self‐Aggregation and Interaction with DNA as Gene Delivery Carriers
Authors: Zhu Yingdan , Sheng Ruilong , Luo Ting , Li Hui , Sun Wenyan , Li Yang , Cao Amin 
Published: October 2010

AbstractA new series of triblock [dendritic poly(L‐lysine)]‐block‐PLLA‐block‐[dendritic poly(L‐lysine)]s (DL2‐PLLA‐DL2) with PLLA block lengths of 11.5–26.5 and double 2‐generation PLL dendrons DL2 as model cationic amphiphiles were synthesized and characterized. Their CAC, self‐aggregation and plasmid DNA binding affinities in pure water and PBS were studied. The PLLA block length dependence of particle size, morphology and ξ potential for organized pDNA/amphiphile polyplex aggregates were examined. Finally, toxicities of these DL2‐PLLA‐DL2 amphiphiles and their polyplexes were assayed by MTT with HeLa, SMMC‐7721 and COS‐7 cells, and COS‐7 cell luciferase and eGFP gene transfection efficacies with these amphiphiles as the delivery carriers were investigated. magnified image
Recent Advances in the Application of Natural Fiber Based Composites
Authors: Pandey Jitendra K. , Ahn S. H. , Lee Caroline S. , Mohanty Amar K. , Misra Manjusri 
Published: October 2010

AbstractNatural fiber reinforced polymer composites are lightweight, economical and available in a variety of forms. They have low densities, comparable material properties, high molding flexibility and are environmentally friendly, making them a conceivable alternative to traditional fillers like mica, calcium carbonate and glass. By modifying either the resin system or the natural fiber, biocomposites can be designed for different applications ranging from products of commodity to aerospace, examples including electroactive papers, fuel cell membranes, controlled drug release mechanisms and biosensors. This review aims to analyze the advancement in the application of cellulose based materials in different sectors with a discussion of fundamental research in these areas. magnified image
High‐Yield Fabrication of PLGA Non‐Spherical Microarchitectures by Emulsion‐Solvent Evaporation Method
Authors: Li Ruifeng , Li Xuemin , Liu Lingrong , Zhou Zhimin , Tang Hongbo , Zhang Qiqing 
Published: October 2010

AbstractRecently, it has been recognized the shape of particles plays an essential role in the design of materials with unique properties. In this study, PLGA non‐spherical microarchitectures, rods and fibers, were fabricated successfully in high yield by single emulsion‐solvent evaporation method in the presence of sodium tripolyphosphate. The assay of PVA residue was carried out and the hydrogen bonds formation was verified as well. The presented data show that viscosity and coagulation agent have a synergistic effect on forming the rod‐ and fiber‐like microarchitectures in the shear response and the formation mechanisms were proposed accordingly. magnified image
Everyday reasoning abilities in persons with Parkinson's disease
Authors: Young Tiffany L. , Granic Antoneta , Yu Chen Tuo , Haley Christine B. , Edwards Jerri D. 
Published: October 2010

AbstractParkinson's disease (PD) patients develop progressive cognitive decline. The degree to which such decline impacts instrumental activities of daily living (IADL) among individuals in the early stages of PD without dementia is not well documented. The Everyday Cognitive Battery Reasoning subtest (ECB) was used to assess ability to solve everyday reasoning tasks for IADL among 19 non‐demented older adults with PD in comparison to 20 older adults without PD. The two groups were similar in age, education, race and gender. Individuals with PD had significantly lower scores (M = 61.98, SD = 12.03) than the comparison group (M = 69.80, SD = 9.48). Individuals with PD, who do not have dementia, may be more likely to experience difficulties in IADL requiring reasoning including medication use, finances, and nutrition. Even more serious implications lie in the capacity to make treatment choices. © 2010 Movement Disorder Society
Myoclonus in Creutzfeldt‐Jakob disease: Polygraphic and video‐electroencephalography assessment of 109 patients
Authors: Binelli Simona , Agazzi Pamela , Canafoglia Laura , Scaioli Vidmer , Panzica Ferruccio , Visani Elisa , Di Fede Giuseppe , Giaccone Giorgio , Bizzi Alberto , Bugiani Orso , Avanzini Guiliano , Tagliavini Fabrizio , Franceschetti Silvana 
Published: October 2010

AbstractWe used electroencephalography (EEG)‐polygraphic recordings to classify myoclonus in 109 patients with Creutzfeldt‐Jakob disease (CJD) on the basis of its electromyography (EMG) pattern, time course, distribution, and EEG correlates. We recorded myoclonic jerks in 55 patients (50.4%), and we classified them as periodic myoclonus in 28, rhythmic in 13, and irregular in 20 (6 patients showed two types of myoclonus). Myoclonus occurred as a prominently negative event (interrupting the EMG discharge) in 10. Periodic sharp‐wave complexes (PSWCs) were present in all but one patient with myoclonic jerks but were time‐locked with EMG‐bursts only in case of periodic myoclonus. Jerk‐locked back averaging revealed a variable EEG‐EMG transfer‐time commonly exceeding that characterizing cortical myoclonus. Myoclonus was frequently associated with Met/Met polymorphism at codon 129 of the prion protein gene, but it was also observed in association with Met/Val or Val/Val polymorphisms provided that the EEG showed the presence of the PSWC pattern. The presence of enlarged somatosensory evoked potentials significantly correlated with the myoclonic presentation, as did MR signal hyperintensity involving the cortical mantle. Our observations on the basis of standard polygraphic criteria suggest that CJD associates with a remarkable variety of myoclonic jerks, and therefore different brain structures are probably involved as generators. The significant association between the presence of all myoclonus types with PSWCs suggests that hyperexcitable corticosubcortical loops are always required to generate (or allow) both myoclonus and the EEG complexes, either they are time locked or not. © 2010 Movement Disorder Society
Sensory disturbances and pain complaints after brachial plexus root injury: A prospective study involving 150 adult patients
Authors: Bertelli Jayme Augusto , Ghizoni Marcos FlÁvio , Loure Iro Chaves Daniel Preissler 
Published: October 2010

AbstractAfter injury of the brachial plexus, sensory disturbance in the affected limb varies according to the extent of root involvement. The goal of this study was to match sensory assessments and pain complaints with findings on CT myelo scans and surgical observations. One hundred fifty patients with supraclavicular stretch injury of the brachial plexus were operated upon within an average of 5.4 months of trauma. Preoperatively, upper limb sensation was evaluated using Semmes‐Weinstein monofilaments. Pain complaints were recorded for each patient. With lesions affecting the upper roots of the brachial plexus, hand sensation was largerly preserved. Sensory disturbances were identified over a longitudinal bundle on the lateral arm and forearm. In C8–T1 root injuries, diminished protective sensation was observed on the ulnar aspect of the hand. If the C7 root also was injured, sensation in the long finger was impaired. Eighty‐four percent of our 64 patients with total palsy reported pain, versus just 47% of our 72 patients with upper type palsies. This rate dropped to 29% in the 14 patients with a lower‐type palsy. C8 and T1, when injured, always were avulsed from the cord; when avulsion of these roots was the only nerve injury, pain was absent. Hand sensation was largely preserved in patients with partial injuries of the brachial plexus, particularly on the radial side. Even when T1 was the only preserved root, hand sensation was mostly spared. This indicates that overlapping of the dermatomal zones seems much more widespread than previously reported. © 2010 Wiley‐Liss, Inc. Microsurgery, 2011.
Reconstruction of the radial forearm free flap donor site using integra artificial dermis
Authors: Murray Ryan C. , Gordin Eli A. , Saigal Kapil , Leventhal Douglas , Krein Howard , Heffelfinger Ryan N. 
Published: October 2010

AbstractAutologous skin grafting to the donor site in patients who undergo radial forearm free flap reconstruction (RFFF) is associated with cosmetic and functional morbidity. Integra artificial dermis (Integra Lifesciences, Plainsboro, NJ) is a bovine collagen based dermal substitute that can be used as an alternative to primary autologous skin transplantation of the donor site. We describe a staged reconstruction using Integra followed by ultrathin skin grafting that results in highly aesthetic and functional outcomes for these defects. A retrospective review of 29 patients undergoing extirpative head and neck oncologic resection were examined. Integra graft placement was performed at the time of RFFF harvest followed by autologous split thickness skin grafting at 1 to 5 weeks postoperatively. Healing fully occurred within 4–6 weeks with negligible donor site complications, excellent cosmesis, and minimal scar contracture. Composite reconstruction with Integra artificial dermis offers advantages over traditional methods of coverage for select cases of radial forearm free flap donor site closures. © 2010 Wiley‐Liss, Inc. Microsurgery, 2011.
One‐sided soft palatal reconstruction with an anterolateral thigh fasciocutaneous flap: Report of two cases
Authors: Tsuchiya Sunao , Nakatsuka Takashi , Sakuraba Minoru 
Published: October 2010

AbstractSoft palate reconstruction is one of the greatest challenges for reconstructive surgeons. In the last 2 decades, anterolateral thigh (ALT) flaps have emerged as a popular reconstructive option because of the low donor morbidity, replacing radial forearm (RF) flaps. For soft palatal reconstructions, however, the RF flap remains the option of first choice, and only a few reports have described soft palatal reconstruction using an ALT flap. At our hospital, ALT flaps were utilized in two cases with soft palatal tumors. During the operation, the nasal side was left unepithelized. To prevent infection of the perforators and pedicles, we dissected a muscle cuff for the perforators and positioned the perforators near the edge of the flap. The postoperative courses were uneventful, and the patients gained almost normal function. ALT fasciocutaneous flaps are a feasible option for soft palatal reconstruction. © 2010 Wiley‐Liss, Inc. Microsurgery, 2011.
Curcumin induces heme oxygenase‐1 in normal human skin fibroblasts through redox signaling: Relevance for anti‐aging intervention
Authors: Lima Cristovao F. , Pereira‐Wilson Cristina , Rattan Suresh I. S. 
Published: October 2010

AbstractScope: Curcumin, a component of the spice turmeric, was tested for its potential hormetic anti‐aging effects as an inducer of mild stress.Methods and results: Early passage young human skin fibroblasts treated with low doses of curcumin (below 20 μM) showed a time‐ and concentration‐dependent induction of heme oxygenase‐1 (HO‐1), followed by compensatory increase in glutathione‐S‐transferase activity, GSH levels and GSH/GSSG ratio. These effects were preceded by induction of oxidative stress (increased levels of reactive oxygen species and DNA damage) and impairment of cells' GSH redox state. Curcumin also induced nuclear factor‐erythroid‐2‐related factor 2 accumulation in the nuclei. The use of the antioxidant N‐acetyl cysteine prevented the induction of HO‐1 by curcumin. Pharmacological inhibition of phosphatidylinositol 3‐kinase, but not other kinases, significantly prevented curcumin‐induced HO‐1 levels, which was corroborated by the induction of phospho‐Akt levels by curcumin. Late passage senescent cells already had higher HO‐1 levels, and further induction of HO‐1 by curcumin was considerably impaired. The induction of stress responses by curcumin in human cells led to protective hormetic effects to further oxidant challenge.Conclusion: Curcumin induces cellular stress responses in normal human skin fibroblasts through phosphatidylinositol 3‐kinase/Akt pathway and redox signaling, supporting the view that curcumin‐induced hormetic stimulation of cellular antioxidant defenses can be a useful approach toward anti‐aging intervention.