bluuebunny/crossref_metadata_2025_split huggingface dataset:
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway
Authors: Wang Chonglong , Yoon Sang‐Hwal , Shah Asad Ali , Chung Young‐Ryun , Kim Jae‐Yean , Choi Eui‐Sung , Keasling Jay D. , Kim Seon‐Won 
Published: June 2010

AbstractFarnesol (FOH) production has been carried out in metabolically engineered Escherichia coli. FOH is formed through the depyrophosphorylation of farnesyl pyrophosphate (FPP), which is synthesized from isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) by FPP synthase. In order to increase FPP synthesis, E. coli was metabolically engineered to overexpress ispA and to utilize the foreign mevalonate (MVA) pathway for the efficient synthesis of IPP and DMAPP. Two‐phase culture using a decane overlay of the culture broth was applied to reduce volatile loss of FOH produced during culture and to extract FOH from the culture broth. A FOH production of 135.5 mg/L was obtained from the recombinant E. coli harboring the pTispA and pSNA plasmids for ispA overexpression and MVA pathway utilization, respectively. It is interesting to observe that a large amount of FOH could be produced from E. coli without FOH synthase by the augmentation of FPP synthesis. Introduction of the exogenous MVA pathway enabled the dramatic production of FOH by E. coli while no detectable FOH production was observed in the endogenous MEP pathway‐only control. Biotechnol. Bioeng. 2010;107: 421–429. © 2010 Wiley Periodicals, Inc.
A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells
Authors: Ferrell Nicholas , Desai Ravi R. , Fleischman Aaron J. , Roy Shuvo , Humes H. David , Fissell William H. 
Published: June 2010

AbstractWe have developed a bilayer microfluidic system with integrated transepithelial electrical resistance (TEER) measurement electrodes to evaluate kidney epithelial cells under physiologically relevant fluid flow conditions. The bioreactor consists of apical and basolateral fluidic chambers connected via a transparent microporous membrane. The top chamber contains microfluidic channels to perfuse the apical surface of the cells. The bottom chamber acts as a reservoir for transport across the cell layer and provides support for the membrane. TEER electrodes were integrated into the device to monitor cell growth and evaluate cell–cell tight junction integrity. Immunofluorescence staining was performed within the microchannels for ZO‐1 tight junction protein and acetylated α‐tubulin (primary cilia) using human renal epithelial cells (HREC) and MDCK cells. HREC were stained for cytoskeletal F‐actin and exhibited disassembly of cytosolic F‐actin stress fibers when exposed to shear stress. TEER was monitored over time under normal culture conditions and after disruption of the tight junctions using low Ca2+ medium. The transport rate of a fluorescently labeled tracer molecule (FITC‐inulin) was measured before and after Ca2+ switch and a decrease in TEER corresponded with a large increase in paracellular inulin transport. This bioreactor design provides an instrumented platform with physiologically meaningful flow conditions to study various epithelial cell transport processes. Biotechnol. Bioeng. 2010;107:707–716. © 2010 Wiley Periodicals, Inc.
Quantitative physiology ofPichia pastorisduring glucose‐limited high‐cell density fed‐batch cultivation for recombinant protein production
Authors: Heyland Jan , Fu Jianan , Blank Lars M. , Schmid Andreas 
Published: June 2010

AbstractPichia pastorishas become one of the major microorganisms for the production of proteins in recent years. This development was mainly driven by the readily available genetic tools and the ease of high‐cell density cultivations using methanol (or methanol/glycerol mixtures) as inducer and carbon source. To overcome the observed limitations of methanol use such as high heat development, cell lysis, and explosion hazard, we here revisited the possibility to produce proteins withP. pastorisusing glucose as sole carbon source. Using a recombinantP. pastorisstrain in glucose limited fed‐batch cultivations, very high‐cell densities were reached (more than 200 gCDW L−1) resulting in a recombinant protein titer of about 6.5 g L−1. To investigate the impact of recombinant protein production and high‐cell density fermentation on the metabolism ofP. pastoris, we used13C‐tracer‐based metabolic flux analysis in batch and fed‐batch experiments. At a controlled growth rate of 0.12 h−1in fed‐batch experiments an increased TCA cycle flux of 1.1 mmol g−1 h−1compared to 0.7 mmol g−1 h−1for the recombinant and reference strains, respectively, suggest a limited but significant flux rerouting of carbon and energy resources. This change in flux is most likely causal to protein synthesis. In summary, the results highlight the potential of glucose as carbon and energy source, enabling high biomass concentrations and protein titers. The insights into the operation of metabolism during recombinant protein production might guide strain design and fermentation development. Biotechnol. Bioeng. 2010;107: 357–368. © 2010 Wiley Periodicals, Inc.
Glycoside hydrolases: Catalytic base/nucleophile diversity
Authors: Vuong Thu V. , Wilson David B. 
Published: June 2010

AbstractRecent studies have shown that a number of glycoside hydrolase families do not follow the classical catalytic mechanisms, as they lack a typical catalytic base/nucleophile. A variety of mechanisms are used to replace this function, including substrate‐assisted catalysis, a network of several residues, and the use of non‐carboxylate residues or exogenous nucleophiles. Removal of the catalytic base/nucleophile by mutation can have a profound impact on substrate specificity, producing enzymes with completely new functions. Biotechnol. Bioeng. 2010;107: 195–205. © 2010 Wiley Periodicals, Inc.
ChemInform Abstract: G2(MP2) Molecular Orbital Study of [H3AlXH3]‐ (X: C, Si, and Ge) and H3AlYH3 (Y: N, P, and As) Complexes.
Authors: Anane Hafid , Jarid Abdellah , Boutalib Abderrahim 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Crystal Structure of Ba5In3F19: A New Structural Type in Fluoride Crystal Chemistry.
Authors: De Kozak A. , Dupont N. , Gredin P. , Riou D. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ab initio Structures of (M2) and (M3) VO2 High Pressure Phases.
Authors: Galy J. , Miehe G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diammonium Titanium Pentafluoride, (NH4)2TiF5, Containing Ti3+.
Authors: Dadachov Mike , Eriksson Lars 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manganese‐Rich Natural Franklinite.
Authors: Doriguetto Antonio C. , Fernandes Nelson G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Orthorhombic InFe0.33Ti0.67O3.33.
Authors: Michiue Yuichi , Brown Francisco , Kimizuka Noboru , Watanabe Mamoru , Orita Masahiro , Ohta Hiromichi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Illuminating Framework: Understanding the Photoluminescence of α‐Cu‐AlCl4.
Authors: Sullivan Roger M. , Martin James D. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Excitations in Polyoxometalate Clusters Observed by Inelastic Neutron Scattering: Evidence for Ferromagnetic Exchange Interactions and Spin Anisotropy in the Tetrameric Nickel(II) Cluster [Ni4(H2O)2 (PW9O34)2]10‐ and Comparison with the Magnetic Properties.
Authors: Clemente‐Juan Juan M. , Andres Hanspeter , Borras‐Almenar Juan J. , Coronado Eugenio , Guedel Hans U. , Aebersold Michael , Kearly Gordon , Buettner Herma , Zolliker Markus 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Excitations in Polyoxometalate Clusters Observed by Inelastic Neutron Scattering: Evidence for Anisotropic Ferromagnetic Exchange Interactions in the Tetrameric Cobalt(II) Cluster [Co4(H2O)2 (PW9O34)2]10‐. Comparison with the Magnetic and Specific Heat Properties.
Authors: Andres Hanspeter , Clemente‐Juan Juan M. , Aebersold Michael , Guedel Hans U. , Coronado Eugenio , Buettner Herma , Kearly Gordon , Melero Julio , Burriel Ramon 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ferromagnetism in Talc‐Like Cobalt‐Phyllosilicates.
Authors: Richard‐Plouet M. , Vilminot S. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tetracyclohexyloxaquaterene.
Authors: Pajewski Robert , Pecak Agnieszka , Ostaszewski Ryszard , Jurczak Janusz 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An o‐Xylyl Cross‐Bridged 5,12‐Dioxocyclam.
Authors: Hubin Timothy J. , Tyryshkin Nickolay , Alcock Nathaniel W. , Busch Daryle H. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Ring Opening of Meso Aziridines Catalyzed by Tridentate Schiff Base Chromium(III) Complexes.
Authors: Li Zhen , Fernandez Monica , Jacobsen Eric N. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Enantioselective Conjugate Addition of 1,3‐Dicarbonyl Compounds to Nitroalkenes.
Authors: Ji Jianguo , Barnes David M. , Zhang Ji , King Steven A. , Wittenberger Steven J. , Morton Howard E. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral Amine‐Catalyzed Asymmetric Baylis—Hillman Reaction: A Reliable Route to Highly Enantiomerically Enriched (α‐Methylene‐β‐hydroxy)esters.
Authors: Iwabuchi Yoshiharu , Nakatani Mari , Yokoyama Nobiko , Hatakeyama Susumi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins in the Presence of Chloramine‐T (CAT).
Authors: Padmavathi V. , Sumathi R. P. , Chandrasekhar Babu N. , Bhaskar Reddy D. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regiospecific Cleavage of a Triazole or Pyrimidine Ring in Nitrotriazolo[1,5‐a]pyrimidones.
Authors: Voronin Victor V. , Ulomsky Eugeny N. , Rusinov Vladimir L. , Chupakhin Oleg N. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Destructive Hydration of 7‐Benzyl‐1‐isopropyl‐5‐methyl‐1,2,4‐triazolo[4,3‐c]pyrimidine During Dimroth Rearrangement.
Authors: Danagulyan G. G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Stille Cyclization Approach to (‐)‐Periplanone‐B: Studies in Alkene‐Selective Ring‐Closing Metathesis and an Improved Chromium(II)‐Mediated Synthesis of (E)‐Alkenylstannanes from Aldehydes.
Authors: Hodgson David M. , Foley Anne M. , Boulton Lee T. , Lovell Peter J. , Maw Graham N. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electroinduced Oxidative Transformation of 2,5‐Dioxabicyclo[4.4.0]decanes into 5‐(1,3‐Dioxolan‐2‐yl)‐ and 5‐(Dimethoxymethyl)pentanoates.
Authors: Ogibin Yuri N. , Terent'ev Alexander O. , Ilovaisky Alexey I. , Nikishin Gennady I. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: P(MeNCH2CH2)3N: An Efficient Promoter for the Reduction of Aldehydes and Ketones with Poly(methylhydrosiloxane).
Authors: Wang Zhigang , Wroblewski Andrzej E. , Verkade John G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carboindation of Carbon—Carbon Triple Bonds: Regioselective Indium‐Mediated Allylation of Functionalized Alkynes and Transformation into Halogen‐Substituted 1,4‐Dienes.
Authors: Klaps Ernst , Schmid Walther 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Azathiolation of Carbon Monoxide.
Authors: Kuniyasu Hitoshi , Hiraike Hiroshi , Morita Masaki , Tanaka Aoi , Sugoh Kunihiko , Kurosawa Hideo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Benzoylation of Dianions: Preparation of Monobenzoylated Derivatives of Symmetrical Secondary Diamines.
Authors: Wang Tao , Zhang Zhongxing , Meanwell Nicholas A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The First Efficient Electrophilic Carbonylation of Ethane with Carbon Monoxide.
Authors: Orlinkov Alexander V. , Akhrem Irena S. , Vitt Sergei V. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of Polyfluorinated Alcohols with Thionyl Chloride.
Authors: Rakhimov A. I. , Vostrikova O. V. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Polyfunctional Aromatic Imines with Zwitterionic Character.
Authors: Coen Serge , Martinet‐Reboul Laurence , Perichaud Alain 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Intramolecular Diels—Alder Reactions of Photochemically Generated trans‐Cycloalkenones.
Authors: Dorr Hilary , Rawal Viresh H. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convenient Syntheses of Chiral 3‐Substituted 2‐Ethynylaziridines.
Authors: Ohno Hiroaki , Toda Ayako , Takemoto Yoshiji , Fujii Nobutaka , Ibuka Toshiro 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantio‐Differentiating Hydrogenation of Methyl 2‐Furoylacetate and Its Analogues over Tartaric Acid‐Modified Raney Nickel.
Authors: Nakagawa Satoshi , Haruna Noriko , Acosta Delicia E. , Endo Tadateru , Sugimura Takashi , Tai Akira 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Titanium(IV) Triflates in the Catalysis of Homoaldol Reactions.
Authors: Martins Evelyn O. , Gleason James L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Pyrrole Derivatives as Antimycobacterial Agents Analogues of BM212.
Authors: Biava Mariangela , Fioravanti Rossella , Porretta Giulio Cesare , Deidda Delia , Maullu Carlo , Pompei Raffaello 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Tin Hydride‐Mediated Radical Cyclization of Secondary Amides Leading to Substituted Pyrrolidinones. Part 2. Application to the Synthesis of Aromatic Kainic Acid Analogues.
Authors: Bryans Justin S. , Large Jonathan M. , Parsons Andrew F. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.