bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of emulgel formulation from Markhamia tomentosa leaf extract: Characterization and in vitro antimicrobial activity against skin isolates
Authors: Oseni Bukola Aminat , Osekita Shunammite Tofunmi , Ibrahim Mutiat Bolanle , Igbokwe Nwamaka Henrietta , Azubuike Chukwuemeka Paul 
Published: May 2024

Objectives:
Skin infections are mild to severe infections often treated with antimicrobial agents. There is an increase in resistance to antimicrobial agents necessitating the search for new medicines. This study developed an emulgel formulation of Markhamia tomentosa leaf extract and evaluated its antimicrobial activity against skin isolates.

Materials and Methods:
A successive extraction of M. tomentosa leaves in five solvents – n-hexane, dichloromethane, ethyl acetate, ethanol, and distilled water was carried out. The activity of the extracts against skin isolates of Staphylococcus aureus, Staphylococcus epidermidis, and Bacillus subtilis was carried out. The distilled water extract was formulated into emulgel, characterized, and evaluated for antimicrobial activity.

Results:
The n-hexane and dichloromethane extracts of M. tomentosa were inactive against all organisms at concentrations used. The ethanol extract was active against S. aureus and S. epidermidis at 200 mg/mL. The ethyl acetate and distilled water extracts were active against S. epidermidis and B. subtilis at 100 and 50 mg/mL, respectively. All emulgel formulations of distilled water extract of M. tomentosa leaves were brown, smooth, and easy to spread on the skin and had a pH of 4.73–5.55. The formulation containing the distilled water extract was more viscous (7784cP) than the blank formulation (6328cP). The formulation was active against S. epidermidis.

Conclusion:
The distilled water extract of M. tomentosa leaves was the most active against S. epidermidis and B. subtilis. Its emulgel formulation had desirable physicochemical properties for application to the skin. Further studies can be carried out toward its development for the treatment of skin infection caused by organisms investigated.
Utility of SHOX2 and RASSF1A gene methylation detection on the residual cytology material from endobronchial ultrasound-guided transbronchial needle aspiration
Authors: Lan Zhihua , Zhang Jing , Yang Fang , Ma Xin , He Rongfang 
Published: May 2024

Objective:
This study aims to assess the effectiveness of Short Stature Homeobox 2 (SHOX2) and RAS Association Domain Family 1 Isoform A (RASSF1A) gene methylation detection in residual liquid-based cytology (LBC) materials from Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) and investigate the diagnostic accuracy of a comprehensive diagnostic approach.

Material and Methods:
Between June 2022 and May 2023, a total of 110 cases that underwent EBUS-TBNA were enrolled in the study. SHOX2 and RASSF1A genes methylation detection using the residual cytological material, LBC, and cell block (CB) were conducted for each EBUS-TBNA case. The sensitivity and specificity of cytology, CB histopathology, SHOX2, and RASSF1A methylation in diagnosing EBUS-TBNA samples were determined based on follow-up data.

Results:
Among the 72 cases confirmed as pulmonary carcinomas, the methylation test yielded positive results in 24 adenocarcinoma cases, 10 squamous cell carcinoma cases, and 14 small cell carcinoma cases. The sensitivity of the comprehensive diagnosis (combining LBC, CB, and methylation detection) in distinguishing metastatic pulmonary epithelial malignancies in mediastinal and hilar lymph nodes or masses from benign lesions was higher (97.22%, 70/72) than that of morphological diagnosis alone (LBC and CB) (88.89%, 64/72; P < 0.05).

Conclusion:
SHOX2 and RASSF1A methylation detection demonstrates a high sensitivity and negative predictive value in the identification of pulmonary epithelial malignancies and holds promise as a valuable ancillary approach to enhance morphological diagnosis of EBUS-TBNA.
دلائل التغيرات البيئية في وادي الأجردي بمحمية الأمام تركي بن عبد الله الملكية خلال فترة الهولوسين
Authors: العنزي مها عواد 
Published: May 2024

يمتد وادي الأجردي في الأجزاء الجنوبية الشرقية من محمية الامام تركي بن عبدالله الملكية شمالي منطقة القصيم ،ويعد هذا الوادي إحدى الشبكات الهيدرولوجية القديمة، التي تشكلت معالهما إبان العصور المطيرة خلال العصر الرباعي المتأخر، حيث يمثل مع امتداده وادي الرمة، ووادي الباطن في الأجزاء الشرقية جزء من نهر عظيم كان يسود في هذه البقاع من المملكة العربية السعودية. تأتي أهمية دراسة التغيرات البيئية في حوض وادي الأجردي في كونها واحدة من الدراسات التي تهدف إلى إعادة بناء البيئة القديمة في هذا الجزء من محمية الإمام تركي بن عبدالله الملكية، وتهدف الدراسة إلى كشف التغيرات البيئية التي حدثت في هذا الجزء من المحمية، وفهم العلاقة بين مجراه القديم ومجرى وادي الرمة خصوصًا في عصر الهولوسين، وثبت أبرز ملامح التغيرات والتبدلات البيئة والمناخية التي تتزامن مع تطور هذا الوادي. اعتمدت الدراسة على استخدام عدد من التقنيات والتحاليل المعملية متمثلة في تقنية الكربون المشع(14C)Radiocarbon Dating وتقنية حيود الأشعة السينية ((XRD X-Ray Diffraction، والتحليل الحجمي للرواسب Grain size analysis ، بجانب العمل الميداني المكثف. قادت نتائج الدراسة إلى بناء تصور ماضي المحمية في هذا الجزء من المملكة العربية السعودية حيث وادي الأجردي الذي شهد نشاطًا في أوائل الهولوسين 9544 – 9695 Cal قبل الحاضر، بالإضافة إلى إعادة بناء الشبكة النهرية القديمة التي سادت إبان العصور المطيرة.
أثر إدارة المعرفة في الأداء المؤسسي: دراسة تطبيقية على أمانة عمان الكبرى
Authors: الجعافرة عامر زعل 
Published: May 2024

هدفت هذه الدراسة إلى التعرف على أثر إدارة المعرفة في الأداء المؤسسي من وجهة نظر موظفي أمانة عمان الكبرى، ولتحقيق أهداف الدراسة تم بناء استبانة لغرض جمع البيانات، وتكونت عينة الدراسة من 89 موظف من أمانة عمان الكبرى المركز الرئيس من المستوى الإداري التنفيذي، وقد تم اختيارهم بطريقة العينة العشوائية البسيطة، وقد تم استخدام مجموعة من الأساليب الإحصائية المناسبة لتحليل بيانات الدراسة. وتوصلت الدراسة إلى نتائج كان من أهمها أن مدى توافر إدارة المعرفة في أمانة عمان من وجهة نظر موظفي الأمانة جاءت بدرجة مرتفعة، كما أن مستوى الأداء المؤسسي في أمانة عمان قد جاء بدرجة مرتفعة وان هنالك أثراً ما بين إدارة المعرفة والأداء المؤسسي. وتوصي الدراسة بضرورة الاستمرار بتوفير المتطلبات الضرورية لإدارة المعرفة للعاملين في أمانة عمان الكبرى من اجل تحسين أداء العاملين فيها، وبالتالي تحقيق أهدافها باستمرار.
Influência da Vontade nos Julgamentos Intelectuais" de Asa Mahan
Authors: Becker Silvério 
Published: May 2024

O capítulo A Influência da Vontade nos Julgamentos Intelectuais trata mais especificamente de uma teoria do conhecimento acerca das relações da liberdade humana com as crenças, opiniões, e julgamentos destes. Nessetexto, Mahan defende que a Vontade influencia, direta, e também indiretamente, os erros de julgamento, quando eles existem; o que torna os seres humanos responsáveis por seus preconceitos e julgamentos errados. Para Asa Mahan, nenhuma de nossas faculdades intelectuais, e tampouco os nossos sentidos, nos enganam; antes, os erros têm sua origem em assunções realizadas indevidamente pelo próprio agente moral - assunções da Vontade - através do uso que ele faz de sua liberdade.
Nietzsche Leitor de Homero: Materiais Artísticos da 'Genealogia da Moral'
Authors: Garcia André Luis Muniz 
Published: May 2024

O objetivo do presente artigo é revisitar o segundo ensaio da Genealogia da moral de Nietzsche, para, a partir dele, mostrar alguns pressupostos estético-teóricos presentes em sua investigação genealógica sobre a memória e o sofrimento. Central para os propósitos desse estudo é o papel, ali, de Homero, mais precisamente, de estratégias e procedimentos artísticos de sua poética.
Caring Nurse Services Increase Patient Satisfaction in the Catheterization Room
Authors: Ginting Apri Chandra Putra , Saputra Rangga , Haeriyah Siti 
Published: May 2024

Background: The nursing profession's caring service is one of the indicators of success in determining patient satisfaction which will have an impact on the quality of customer satisfaction in the health facility.Objective: The purpose of the study is to determine the relationship between caring nurse services and patient satisfactionMethods: Correlational descriptive with a cross sectional approach. Results: The results of the univariate analysis showed that caring nurse services were sufficient (53.3%) in the Catheterization Room of EMC Alam Sutera Hospital, South Tangerang City and most patients said they were satisfied (56.7%) with caring care services. The results of the bivariate analysis show that there is a strong relationship between caring nurse services and patient satisfaction in the Catheterization Room of EMC Alam Sutera Hospital, South Tangerang City in 2022 (p value: 0.001, correlation 0.579).Conclusion: There is a strong relationship between caring nurse services and patient satisfaction in the Catheterization Room of EMC Alam Sutera Hospital, South Tangerang City
Deep Vein Thrombosis of Saphenous-Femoral Junction After Leg Lauromacrogol Foam Ultrasound Guided Percutaneous Sclerotherapy
Authors: Quarato Marco , Lacavalla Ilaria 
Published: May 2024

Background: Lauromacrogol foam sclerotherapy is characterized by a high success rate in obliterating varicose veins and a low frequency of adverse effects. Most of these parts consist of minor effects, and few data are available about significant effects (e.g., vein thrombosis), pointing out the technical safety of ultrasound-guided foam sclerotherapy.Case Presentation: a 78-year-old woman was evaluated for chronic vein disease; at ultrasonographic and Doppler scan (USDS), severe GSV dilatation and GSV reflux were documented in both legs below the knee. After meticulous anamnesis and physical examination, informed consent was obtained, and ultrasound-guided percutaneous polidocanol foam (one part of 2% lauromacrogol solution + one part of the air, mixed with Double Syringe System) sclerotherapy was performed in the right leg; best medical therapy was given after the procedure. After five days, USDS pointed out thrombosis extending to the thigh upper region to saphenous-femoral junctions, consisting of deep vein thrombosis. Appropriate anticoagulant therapy was promptly dispensed, and the patient had no aftermaths.Conclusion:The prevalence of vein thrombosis after lauromacrogol sclerotherapy is unknown, and their correlation is uncertain, but, in our experience, it should be suspected in patients who referred lower limb pain after this procedure despite the best medical therapy dispensation.
GENDER AND THE USE OF LOCAL LANGUAGE IN URBAN COMMUNITY
Authors: Rizki Dini , Kurniawati Kurniawati , Hanif Hanif , Kiram M. Zawil 
Published: May 2024

In communicating, the use of local languages tends to be influenced by the gender of the speakers. This includes politeness, vocabulary selection, grammar, and context. The urban community is most potentially affected by modernization which also influences the use of local languages. This study looks at the differences in the use of local languages and the causes of these differences based on the gender of the speakers. This study used a qualitative descriptive method using data collection techniques consisting of observation, in-depth interviews, and Focus Group Discussion (FGD). This research was conducted with the subject of urban communities living in the city of Takengon. The results of this study show that urban women and men use local language differently, especially in terms of their preference in using local language. Urban women tend to be affected by the feeling of wanting to be associated with being modern, while urban men are more affected by the context in which they interact. These results are hoped to add to the literature on the use of local languages that can contribute to language maintenance efforts.Dalam berkomunikasi, penggunaan bahasa daerah cenderung dipengaruhi oleh gender dari penuturnya. Perbedaan penggunaan bahasa pada gender yang berbeda ini termasuk perbedaan dalam aspek kesopanan, pemilihan kosa kata, tata bahasa, dan konteks. Masyarakat perkotaan paling berpotensi terkena dampak modernisasi yang juga mempengaruhi penggunaan bahasa daerah. Kajian ini melihat perbedaan penggunaan bahasa daerah dan penyebab perbedaan tersebut berdasarkan jenis kelamin penuturnya. Penelitian ini menggunakan metode deskriptif kualitatif dengan teknik pengumpulan data yang terdiri dari observasi, wawancara mendalam, dan Focus Group Discussion (FGD). Penelitian ini dilakukan dengan subjek masyarakat perkotaan yang tinggal di kota Takengon. Hasil penelitian ini menunjukkan bahwa perempuan dan laki-laki perkotaan menggunakan bahasa daerah secara berbeda, terutama dalam hal preferensi mereka dalam menggunakan bahasa daerah. Perempuan urban cenderung dipengaruhi oleh perasaan ingin diasosiasikan dengan modern, sedangkan laki-laki urban lebih dipengaruhi oleh konteks di mana mereka berinteraksi. Hasil ini diharapkan dapat menambah literatur penggunaan bahasa daerah yang dapat berkontribusi dalam upaya pemertahanan bahasa.
PROGRAM BANTUAN SOSIAL LISTRIK GRATIS BAGI MASYARAKAT MISKIN DI KECAMATAN KRUENG SABEE KABUPATEN ACEH JAYA
Authors: Audina Mirna , Saputra Akmal 
Published: May 2024

This article aims to explain the impact of the free electricity social assistance program for the poor in Aceh Jaya District. This program has been running since 2014 until now. The aim of this program is providing access to electricity while reducing the economic burden of expenses for the poor. This research uses a qualitative method with data collection techniques through in-depth interviews as well as supported by documents that support this research, especially documents that make and implement policies. Data analysis techniques were carried out through several stages, namely data reduction, data presentation and drawing conclusions. The results of the study show that the free electricity social assistance program, in the form of a new electricity installation or installation as well as electricity vouchers has a significant impact. The community is greatly assisted by the program currently being implemented by the government. On the other hand, the free electricity social assistance program also has another impact on the poor, namely the emergence of community dependence on the free electricity social assistance program.Program bantuan sosial listrik gratis adalah pemberian bantuan sosial yang disalurkan kepada masyarakat kurang mampu berupa voucher listrik dan pemasangan instalasi listrik. Syarat penerima bantuan sosial listrik gratis adalah keluarga miskin. Program listrik gratis ini berjalan di Aceh Jaya dari tahun 2014 sampai sekarang. Tujuan dari bantuan sosial listrik gratis ini adalah untuk memberikan akses listrik kepada rumah tangga miskin dan mengurangi beban keluarga miskin dalam memenuhi kebutuhan sehari-hari di wilayah kabupaten tersebut. Penelitian ini memiliki tujuan untuk mengetahui dampak positif dari suatu program bantuan sosial listrik gratis dan dampak negatif dari program bantuan sosial listrik gratis dan mengidentifikasikan terkait ketergantungan bantuan sosial listrik gratis. Lokasi penelitian ini berada di Kecamatan Krueng Sabee kabupaten Aceh Jaya dengan menggunakan metode penelitian kualitatif dengan pendakatan deskriptif. Hasil penelitian menunjukkan bahwa dampak positif dari bantuan listrik gratis adalah terbentuknya minimal masyarakat tidak hidup dalam gelap-gelapan karna sudah ada listrik dan dampak negatif bantuan listrik bagi masyarakat miskin adanya ketergantungan keluarga miskin terhadap bantuan ini.
AGAMA DAN PROBLEMATIKA MASYARAKAT: FUNGSI TASAWUF DALAM PENDIDIKAN, SOSIAL DAN AKHLAK
Authors: A. Samad Sri Astuti , Nurdin Abidin , Samad Munawwarah , Gade Fihriani 
Published: May 2024

Islam entered the archipelago peacefully brought by Sufi scholars and is influential to this day. Sufism is a dimension of Islamic teachings that is able to answer the problems of society from the past to the present. Sufi scholars also fought against colonialism supported by Sufi brotherhood or tariqa in which there was a concept of obedience to the teacher. The reformulation of classical Sufism which is individual, personal, is important enough to become a communal collective. This article is a qualitative study analyzed using the perspective of sociology of religion. Today, Sufism remains important in various aspects of education, social movements, and moral improvement. If using the perspective of sociology of religion, Sufism is able to provide spirit and strength to humans so that Sufism values transform for the better. The values of Sufism in question are for example, qana'ah, patience, gratitude which provide solutions to the problems of human life. Not only limited to educational, social and moral improvement aspects but more than that.Islam masuk ke Nusantara secara damai dibawa oleh para ulama sufi dan berpengaruh sampai saat ini. Tasawuf merupakan dimensi ajaran Islam yang mampu menjawab problematika masyarakat sejak pada masa lalu sampai sekarang. Ulama sufi juga melakukan perlawanan terhadap kolonialisme yang didukung oleh persaudaraan sufi atau tarekat yang di dalamnya terdapat konsep ketaatan pada guru. Reformulasi tasawuf klasik yang bersifat individual personal cukup penting menjadi kolektif komunal.Artikel ini merupakan studi kualitatif yang dianalisis dengan menggunakan perspektif sosiologi agama. Saat ini kemudian bangsa Indonesia semakin maju sufisme tetap menjadi sesuatu yang urgen dalam berbagai aspek pendidikan, gerakan sosial, dan perbaikan akhlak. Jika menggunakan perspektif sosiologi agama, bahwa tasawuf mampu memberikan spirit dan kekuatan pada manusia sehingga nilai-nilai tasawuf bertransformasi ke arah yang lebih baik. Nilai-nilai tasawuf yang dimaksud misalnya, qana’ah, sabar, syukur yang memberikan solusi problematika kehidupan manusia. Tidak hanya sebatas aspek pendidikan, social dan perbaikan akhlak akan tetapi lebih dari itu.
Harnessing CFD simulations and CAD design to optimize hydropower efficiency of a propeller turbine in the Maliringan River: acase study
Authors: Nathanlius David , Halim Levin , Arthaya Bagus Made 
Published: May 2024

This research focuses on improving hydropower production by designing a turbine for the MaliringanRiver in Kalimantan Selatan. The rotational speed and torque will be the focus of maximizing power generation. This research used Computational Fluid Dynamics (CFD) to understand how the fluid flows and how efficiently the turbine works. The simulations helped us see how the fluid flowed, the pressure differences, and the speed of the water inside the turbine. The software COMSOL Multiphysics imitates how the fluid behaves and interacts in real-life situations. The utilization of SOLIDWORKS played a crucial role in the turbine's design process, facilitating an accurate representation of the turbine's geometry and the subsequent fabrication of a prototype propeller turbine, featuring an outer diameter measuring 0.27 meters and an inner diameter measuring 0.113 meters. The methodology resulted in a power efficiency of 76.45%, showcasing the possibility of significant enhancements in the efficiency of hydropower generation. The broader ramifications of this study emphasize the feasibility of tailor-made turbines for local hydropower initiatives, thereby supporting Indonesia's renewable energy plan by providing sustainable and efficient energy alternatives. This study emphasizes the collaborative utilization of Computer-Aided Design (CAD) and CFD technologies in the progression of turbine technology, thereby establishing a basis for future investigations in hydropower optimization.
Book Reviews
Authors: Freerks Vanessa , Aihiokhai SimonMary Asese A. 
Published: May 2024

Abraham Olivier, M. John Lamola and Justin Sands, Eds., Phenomenology in an African Context: Contributions and Challenges, 2023. State University of New York Press, 353pp. ISBN: 9781438494876 (hbk)
Elias Opongo and Tim Murithi, Eds., Elections, Violence and Transitional Justice in Africa Elections, Violence and Transitional Justice in Africa, 2022. Routledge, 202 pp. ISBN: 9780367655280 (hbk)
Perancangan Sistem Kompensasi Berbasis Job Value Pada RM Terapung Minahasa Utara
Authors: Gultom Shekinah Michelle , Rahmawati Siti 
Published: May 2024

ABSTRAK: RM Terapung Minahasa Utara merupakan salah satu badan usaha pada industri makanan dan minuman yang terletak di Kabupaten Minahasa Utara. Namun dalam pelaksanaannya, RM Terapung Minahasa Utara belum mampu memberikan gaji sesuai upah minimum yang berlaku. Penelitian ini bertujuan untuk mengidentifikasi sistem kompensasi yang diterapkan oleh rumah makan, menganalisis faktor-faktor dasar untuk penetapan kompensasi (compensable factors), serta merancang sistem kompensasi yang ideal untuk diterapkan di RM Terapung Minahasa Utara. Penelitian ini dilakukan pada bulan Februari 2023–April 2023. Metode yang digunakan pada penelitian ini menggunakan metode analisis deskriptif, metode poin, nilai pekerjaan, pengelompokan pekerjaan, pemetaan gaji, serta metode adhered dan overlapping. Data primer diperoleh dari hasil observasi serta wawancara terstruktur, dan data sekunder yang diperoleh dari studi literatur. Faktor-faktor kompensasi yang digunakan pada RM Terapung Minahasa Utara yaitu pengalaman kerja, keahlian, kerja sama, berkomunikasi dan memengaruhi, orientasi pelayanan pelanggan, pemecahan masalah, usaha fisik, kompleksitas pekerjaan, dan tanggung jawab. Sistem kompensasi yang ideal untuk diterapkan adalah sistem kompensasi adhered yang terletak pada range min–mid point. Kata Kunci: gaji, job value, sistem kompensasi
Life Stress and Coping Strategies of Chittagong University Students
Authors: Dey Biplob Kumar , Hossain Mohammad Afzal , Bairagi Arunavo , Rahman Abdur , Sarkar Pulak Kumar 
Published: May 2024

The purpose of the present study was to investigate life stress and coping strategies of Chittagong university students. The sample of the study consisted of 120 university students of whom 60. students were first year (30 male and 30 female) and remaining 60 was masters (30 male and 30 female). Each group again consisted of 15 science students and 15 arts students. They were selected purposively from Chittagong University and some residential areas of Chittagong. The ·Bengali version of the "Life Stress Questionnaire" (Fahim 2001 ) and "coping scale" (Huque 2004) were used for investigating the life stress and coping strategies ·respectively. ·The obtained data were analyzed by using t-test. Results reveal that the life stress of masters’ students were greater than first year students (t=2.87, df= l 18,· p<0.05); the life stress of female students were more compared to the male students (t=2.07 ; - df= 118;: -p<0.05); the problem focused coping strategies of masters students were more compared to first year students (t=9.24; df=58, p<0.05); whereas the emotion focused coping strategies of first year were more compared to masters' students; the problem focused coping strategies of male students were more compared · to female students ··strategies between male and female students and also there was no significant difference between science and arts faculties students in life stress and coping strategies.
The Chittagong Univ. J. B. Sci. 8(1&2):37-50,203