bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and Perceptions of Texas Community Pharmacists Regarding Electronic Nicotine Delivery Systems
Authors: Wollen Joshua , Kochuparambil Priyanka , Singh Harleen , Mottley Olivia , Rosario Natalie 
Published: June 2024

Abstract

Background:
Electronic nicotine delivery systems (ENDS) have gained popularity in the United States among adults and adolescents for social use and as a smoking cessation tool. The increase of ENDS use leads to concerns about their impact on public health. In the United States, ENDS are readily available for purchase and pose risks. Community pharmacists can play a crucial role in educating adult and adolescent patients about ENDS.
Objectives:
This study aimed to understand Texas community pharmacists' perceptions of ENDS with three objectives: 1) to identify consensus on perceptions and comfort among community pharmacists in Texas and 2) assess basic knowledge of the ENDS use landscape in the United States.
Methods:
A cross-sectional survey targeting community pharmacists in Texas was conducted in 2019. Sixty-eight responses were collected, and 43 were included in the analysis. The survey covered pharmacist demographics and ENDS questions related to knowledge and perceptions or ENDS and a ranking question of tobacco cessation strategies.
Results:
Most respondents 40 or more years of practice. Respondents expressed low confidence in ENDS as an effective smoking cessation tool. Nicotine replacement therapy was considered the most effective method, while e-cigarettes were deemed the least effective. Knowledge about ENDS was limited, with significant gaps in understanding.
Conclusion:
Community pharmacists in Texas require additional education and knowledge enhancement regarding ENDS. This study highlights the urgent need for more comprehensive ENDS education in pharmacy curricula and continuing education to equip pharmacists with the knowledge to counsel patients on ENDS effectively.
Enhanced denitrification by graphene oxide–modified cathode for the secondary effluent of wastewater treatment plants in three-dimensional biofilm electrode reactors
Authors: Xue Ying , Zhang Chaojie , Li Sibo , Zhou Qi , Zhou Xuefei , Zhang Yalei 
Published: June 2024

ABSTRACT

In this study, a novel three-dimensional biofilm electrode reactor (3D-BER) with a graphene oxide (GO)–modified cathode was developed to enhance the denitrification performance of secondary effluent from wastewater treatment plants (SEWTPs). The effects of different hydraulic retention times (HRTs) and currents on the 3D-BER were explored. The results indicated that at the optimal HRT of 4 h and current of 350 mA/m2, the 3D-BER with GO-modified cathode had a higher denitrification rate (2.40 ± 0.1 mg TN/L/h) and less accumulation of intermediate products, especially with 3.34% total nitrogen (TN) molar conversion to N2O. The GO-modified cathode offered a large biocompatible specific surface area and enhanced the conductivity, which favored microbial growth and increased electron transfer efficiency and extracellular enzyme activities. Moreover, the activity of nitrite reductase increased more than that of nitrate reductase to accelerate nitrite reduction, thus facilitating the denitrification process. The proposed 3D-BER provided an effective solution to elevate tertiary denitrification in the SEWTP.
An Analogy between Two Bio-Membranes (CGF-PRGF) Mixed with Xenogeneic Bone Graft to Achieve Frugal Management of Labial Dehiscence amidst Immediate Implantation in Esthetic Zone: A Randomized Clinical Trial
Authors: Fathy Abo-elkheir Hussein , Moustafa Ahmed Abdel Meguid , Khalil Ahmed Abdallah 
Published: June 2024

Background
Labial dehiscence is a very prevalent esthetic concern among implantologists during immediate implantation in the esthetic zone since recent implant treatment and patient ambition are not only directed to function reestablishment, but esthetic superbness also holds immense consideration.

Objective
This study aimed to manage the labial dehiscence at the time of implantation and evaluate and compare the effects of two different autologous biomembranes, Concentrated Growth Factor (CGF) and Plasma Rich Growth Factors (PRGF), in combination with xenogeneic bone around the immediate implants in the esthetic zone.

Methods
Twenty patients indicated for immediate implant in the esthetic zone were randomly divided into two groups. The first group received CGF with xenograft, and the second group received PRGF mixed with xenograft. Cone Beam Computed Tomography (CBCT) radiographs and clinical periodontal parameters were evaluated, and all the results were tabulated and statistically analyzed.

Results
The two groups showed a statistically significant increase in bone density and inevitable crestal bone loss after 9 months, even though the CGF group comparably showed a statistically significant reduction in crestal bone loss.

Conclusion
Platelet concentrate derivatives, such as CGF and PRGF, are beneficial in the management of labial dehiscence around the immediate implants even though CGF offers a considerably and statistically significant decrease in crestal bone loss and more amelioration of bone density alongside its easier and faster preparation than PRGF.

Clinical Trial Registration
The study is registered at the U.S. National Library of Medicine website of clinical trials (clinicaltrials.gov) under ID: NCT05595772.
Prevalence of Dentin Hypersensitivity Among Dental Students and Effectiveness of Tooth Desensitizing Agents
Authors: Islam Md. Sofiqul , Padmanabhan Vivek , Al Abid Hanan Khalil , Khallaf Ebtessam Ahmad Abouelnaga , Rahman Muhammed Mustahsen , Aryal A C Smriti 
Published: June 2024

Objectives
Dentin hypersensitivity (DH) is a growing concern in Dentistry. The objective of this study was to evaluate the prevalence and effectiveness of different desensitizing agents of (DH) among undergraduate dental students.

Materials and Methods
This cross-sectional clinical study was conducted with 161 undergraduate dental students. A self-reporting questionnaire along with a clinical examination was performed to diagnose DH and determine the severity. The effectiveness of home-based and in-office desensitizers was evaluated by comparing the combined DH scale in the pre- and post-treatment periods. The data were analyzed for frequency, correlation, and T-test.

Results
The prevalence of DH in the tested population was 19.3%, predominantly in females. The Chi-Square test showed significance in gender and oral hygiene practice by the participants (p<0.05). However, none of the tested factors strongly correlated with DH in this population. The post-treatment combined DH scale (5.48±3.1) was statistically significant (p=0.0001) compared to the pretreatment scale (11.29±3.5). The effectiveness of SRA was 87%, and the remaining 13% of DH recovered using GLUMA.

Conclusion
The prevalence of DH was 19.3% without any strongly correlated etiology. Home-based and in-office desensitizers were effective in reducing DH in the tested population.
K’abeena phonology
Authors: Girma Tadesse 
Published: June 2024

The article provides descriptive analysis of the phonology of K'abeena, a language belonging to the Afro-Asian phylum, spoken in central Ethiopia. In this article, I identify 25 consonant phonemes and 3 loan phonemes. The loan phonemes are included as they are used in the current language's orthography. The language has five vowels. Vowel length and Gemination of consonants are phonemic in the language. With the exception of /h/ and /f/, which never geminate in the language, the rest of the consonant phonemes appear together to geminate. This only happens in the medial position of the words. Consonant clusters are allowed in word medial position with a maximum of two consonants. The phonological process identified in this article involves processes like assimilation, palatalization and deletion. Kabeena does not appear to be a pitch-accent language, but further research is needed to establish confirmed statements.
Wayfinding Analysis for Evacuation Optimization with Urban Network Analysis in Disaster Preparedness School KB TK Masjid Syuhada
Authors: Setyawan Siti Luzviminda Harum Pratiwi , Syafii Nedyomukti Imam 
Published: June 2024

The existence of evacuation routes is one of the most important elements in disaster management because it will determine the smoothness of the rescue process during a disaster. An evacuation route is a route to an assembly point or exit that is assumed to be a safe space. Wayfinding is the process of moving from one point to another within the closest or fastest distance. In relation to the evacuation process, wayfinding will show the movement from a point, which in relation to buildings can be a specific space, to an exit or assembly point. As one of the disaster preparedness schools in Yogyakarta's Special Region, Masjid Syuhada Kindergarten was chosen as the site of the research. It is a complex of schools ranging from playgroup, kindergarten, elementary school, to junior high school, all of which are connected by the Syuhada Mosque. The analysis of evacuation routes in the kindergarten was conducted using Urban Network Analysis (UNA). UNA is used as a method to determine the effectiveness of providing evacuation routes in a building area because it can analyze trips between points, called origin and destination. Of the various analyses that UNA can perform, this research uses the closest facility analysis. In this study, the origins were all the class in the kindergarten which placed at the door as the open access and in the middle of the class if the class have two doors; while the destinations were the stairs which heading to assembly point. The conclusion is reached after analyzing the network that connects the origin of the class to the destination of the stairs, which is connected to the assembly point.
Tantangan dan Kebutuhan Guru SDLB dalam Implementasi Kurikulum Merdeka Di Lampung
Authors: Wardany Ossy Firstanti , Sani Yulvia , Herlina Heni , Setyaningsih Septi 
Published: June 2024

Transisi dari Kurikulum 2013 ke Kurikulum Merdeka bagi PDBK (Peserta Didik Berkebutuhan Khusus) diasumsikan menimbulkan tantangan baru bagi guru dalam mengimplementasikannya. Penelitian bertujuan menggali tantangan dan merumuskan kebutuhan guru Sekolah Dasar Luar Biasa (SLB) dalam implementasi Kurikulum Merdeka bagi PDBK di jenjang SD. Penelitian merupakan penelitian kuantitatif dengan menggunakan metode survei. Responden penelitian adalah 44 guru SLB tingkat Sekolah Dasar di Provinsi Lampung yang menerapkan Kurikulum Merdeka yang dipilih secara random sampling. Pengumpulan data menggunakan penyebaran kuesioner dengan Google Form. Hasil penelitian menunjukkan bahwa guru telah memiliki pemahaman yang baik, pandangan positif dan kesiapan yang cukup mengenai Kurikulum Merdeka yang didukung dari pengalaman belajar melalui berbagai kegiatan dari pemerintah, sekolah, dan pihak lain. Dari 44 guru tersebut, 55% guru merasa kekurangan waktu dalam merancang evaluasi yang sesuai dengan keragaman jenis dan fase peserta didik, 59% guru merasa pilihan keterampilan vokasional yang ada di sekolah masih terbatas, 48% masih kesulitan dalam membuat instrumen asesmen awal, dan 45% mengalami masalah dalam melaksanakan pembelajaran yang mengakomodasi keberagaman. Tantangan ini selaras dengan kebutuhan yang diinginkan guru, di mana 3 kebutuhan teratas yakni 84% mengharapkan pelatihan mengenai metode dan media pembelajaran yang berdiferensiasi, 77% membuat asesmen dan rencana pembelajaran, 77% pelatihan program kebutuhan khusus.
Pengaruh Teman Sebaya, Minat Belajar, dan Kreativitas Siswa Terhadap Prestasi Belajar Akuntansi Keuangan
Authors: Siswanto Siswanto , Rosa Laksmita 
Published: June 2024

Penelitian ini bertujuan untuk mengetahui Pengaruh Teman Sebaya, Minat Belajar, dan Kreativitas Siswa terhadap Prestasi Belajar Akuntansi Keuangan. Penelitian ini merupakan jenis penelitian ex-post facto. Objek penelitian adalah siswa kelas XI Akuntansi Keuangan Lembaga SMK Negeri 1 Batealit Jepara dengan jumlah 72 siswa. Metode pengumpulan data yang digunakan adalah kuesioner. Teknik analisis data yang digunakan ialah analisis regresi. Hasil penelitian menunjukkan bahwa: (1) Terdapat pengaruh positif Teman Sebaya terhadap Prestasi Belajar Akuntansi Keuangan dengan koefisien regresi (r1x1)sebesar 0,386; dan : 3,505; (2) Terdapat pengaruh positif Minat Belajar terhadap Prestasi Belajar Akuntansi Keuangan dengan nilai koefisien regresi (r2x2 ) sebesar 0,210; dan : 2,093. (3) Terdapat pengaruh positif Kreativitas Siswa terhadap Prestasi Belajar Akuntansi Keuangan dengan nilai koefisien regresi (r3x3 ) sebesar 0,142; dan 417; (4) Terdapat pengaruh positif Teman Sebaya, Minat Belajar, dan Kreativitas Siswa terhadap Prestasi Belajar Akuntansi Keuangan dengan koefisien korelasi (Ry123 ) sebesar 0,706; koefisien determinasi ( R2y123)sebesar 0,498.
Analisis Peluang Kerja Lulusan Pendidikan Administrasi Perkantoran dalam Rekrutmen Pegawai Pemerintah Kelompok Teknis 2022
Authors: Rusdiyanto Wahyu , Ismawati Junica , Zulkarnaen Zulkarnaen 
Published: June 2024

Penelitian ini bertujuan untuk menganalisis peluang kerja lulusan pendidikan administrasi perkantoran pada rekrutmen Pegawai Pemerintah dengan Perjanjian Kerja (PPPK) Teknis Tahun 2022. Penelitian ini menggunakan metode analisis konten dengan pendekatan kualitatif. Pengumpulan data dalam penelitian ini menggunakan dokumentasi tentang informasi jenis pengadaan, instansi, serta tingkat pendidikan. Sumber data dalam penelitian ini yaitu website resmi rekrutmen PPPK (sscasn.bkn.go.id). Selanjutnya, data dianalisis untuk mendapatkan informasi jenis formasi jabatan dan instansi yang membuka lowongan. Analisis deskriptif digunakan untuk mendapatkan informasi jenis lowongan pekerjaan dan kantor pemerintah penyedia lowongan pekerjaan. Hasil penelitian menunjukkan bahwa terdapat 1901 peluang kerja untuk lulusan Pendidikan Administrasi Perkantoran. Peluang kerja terbanyak berada di Kementerian Agama. Formasi pekerjaan yang tersedia yaitu arsiparis dan analis kebijakan. Namun, lulusan pendidikan administrasi perkantoran harus bersaing dengan lulusan program studi lain yang layak mengisi formasi tersebut.
The Effect of Artificial Intelligence on Patient-Physician Trust: Cross-Sectional Vignette Study
Authors: Zondag Anna G M , Rozestraten Raoul , Grimmelikhuijsen Stephan G , Jongsma Karin R , van Solinge Wouter W , Bots Michiel L , Vernooij Robin W M , Haitjema Saskia 
Published: June 2024

Background
Clinical decision support systems (CDSSs) based on routine care data, using artificial intelligence (AI), are increasingly being developed. Previous studies focused largely on the technical aspects of using AI, but the acceptability of these technologies by patients remains unclear.

Objective
We aimed to investigate whether patient-physician trust is affected when medical decision-making is supported by a CDSS.

Methods
We conducted a vignette study among the patient panel (N=860) of the University Medical Center Utrecht, the Netherlands. Patients were randomly assigned into 4 groups—either the intervention or control groups of the high-risk or low-risk cases. In both the high-risk and low-risk case groups, a physician made a treatment decision with (intervention groups) or without (control groups) the support of a CDSS. Using a questionnaire with a 7-point Likert scale, with 1 indicating “strongly disagree” and 7 indicating “strongly agree,” we collected data on patient-physician trust in 3 dimensions: competence, integrity, and benevolence. We assessed differences in patient-physician trust between the control and intervention groups per case using Mann-Whitney U tests and potential effect modification by the participant’s sex, age, education level, general trust in health care, and general trust in technology using multivariate analyses of (co)variance.

Results
In total, 398 patients participated. In the high-risk case, median perceived competence and integrity were lower in the intervention group compared to the control group but not statistically significant (5.8 vs 5.6; P=.16 and 6.3 vs 6.0; P=.06, respectively). However, the effect of a CDSS application on the perceived competence of the physician depended on the participant’s sex (P=.03). Although no between-group differences were found in men, in women, the perception of the physician’s competence and integrity was significantly lower in the intervention compared to the control group (P=.009 and P=.01, respectively). In the low-risk case, no differences in trust between the groups were found. However, increased trust in technology positively influenced the perceived benevolence and integrity in the low-risk case (P=.009 and P=.04, respectively).

Conclusions
We found that, in general, patient-physician trust was high. However, our findings indicate a potentially negative effect of AI applications on the patient-physician relationship, especially among women and in high-risk situations. Trust in technology, in general, might increase the likelihood of embracing the use of CDSSs by treating professionals.
Connecting Female Entertainment Workers in Cambodia to Health Care Services Using mHealth: Economic Evaluation of Mobile Link
Authors: Avanceña Anton L V , Brody Carinne , Chhoun Pheak , Tuot Sovannary , Yi Siyan 
Published: June 2024

Background
Mobile Link is a mobile phone–based intervention to increase access to, and use of, health care services among female entertainment workers in Cambodia who face higher risks for specific diseases and gender-based violence. A multisite randomized controlled trial showed that Mobile Link connected female entertainment workers with outreach workers for information and escorted referrals after 6 months but did not lead to statistically significant improvements in HIV and sexually transmitted infection testing, contraceptive use, and condom use.

Objective
This study aims to conduct a 3-part economic evaluation of Mobile Link to understand its costs, value, and affordability.

Methods
We conducted cost, cost-effectiveness, and budget impact analyses of Mobile Link using cost and outcomes data from the Mobile Link trial and other sources. For the cost analysis, we estimated the total, per-person, and incremental costs of Mobile Link compared with usual care. Using probabilistic decision-analytic models, we estimated the 1-year cost-effectiveness of Mobile Link from payer and combined payer and patient perspectives by converting selected primary and secondary outcomes from the trial to disability-adjusted life years (DALYs) averted. Finally, we estimated the financial costs of scaling up Mobile Link’s messaging and outreach services to 70% of female entertainment workers in 5 years.

Results
The incremental costs of Mobile Link were US $199 from a payer perspective and US $195 per person from a combined payer and patient perspective. With an average of 0.018 (95% predicted interval –0.088 to 0.126) DALYs averted, Mobile Link’s cost-effectiveness was US $10,955 per DALY from a payer perspective (US $10,755 per DALY averted from a payer and patient perspective). The costs of Mobile Link would have to decrease by 85%, or its effectiveness would have to be 5.56 times higher, for the intervention to meet the upper limit of recommended cost-effectiveness thresholds in Cambodia (US $1671 per DALY averted). The 5-year cost of scaling Mobile Link to 34,790 female entertainment workers was estimated at US $1.64 million or US $46 per person per year.

Conclusions
This study provided a comprehensive economic evaluation of Mobile Link. We found that Mobile Link is not likely to be cost-effective unless its costs decrease or its effectiveness increases. Scaling up Mobile Link to more female entertainment workers is estimated to cost less than the costs of the trial. Given the importance of linking female entertainment workers to essential services, future research should focus on enhancing the effectiveness of Mobile Link or developing new mobile health interventions for this population.

Trial Registration
ClinicalTrials.gov NCT03117842; https://clinicaltrials.gov/study/NCT03117842
Trend of Mortality Due to Congenital Anomalies in Children Younger Than 5 Years in Eastern China, 2012-2021: Surveillance Data Analysis
Authors: Dong Wen-Hong , Guo Jun-Xia , Wang Lei , Zheng Shuang-Shuang , Zhu Bing-Quan , Shao Jie 
Published: June 2024

Background
As one of the leading causes of child mortality, deaths due to congenital anomalies (CAs) have been a prominent obstacle to meet Sustainable Development Goal 3.2.

Objective
We conducted this study to understand the death burden and trend of under-5 CA mortality (CAMR) in Zhejiang, one of the provinces with the best medical services and public health foundations in Eastern China.

Methods
We used data retrieved from the under-5 mortality surveillance system in Zhejiang from 2012 to 2021. CAMR by sex, residence, and age group for each year was calculated and standardized according to 2020 National Population Census sex- and residence-specific live birth data in China. Poisson regression models were used to estimate the annual average change rate (AACR) of CAMR and to obtain the rate ratio between subgroups after adjusting for sex, residence, and age group when appropriate.

Results
From 2012 to 2021, a total of 1753 children died from CAs, and the standardized CAMR declined from 121.2 to 62.6 per 100,000 live births with an AACR of –9% (95% CI –10.7% to –7.2%; P<.001). The declining trend was also observed in female and male children, urban and rural children, and neonates and older infants, and the AACRs were –9.7%, –8.5%, –8.5%, –9.2%, –12%, and –6.3%, respectively (all P<.001). However, no significant reduction was observed in children aged 1-4 years (P=.22). Generally, the CAMR rate ratios for male versus female children, rural versus urban children, older infants versus neonates, and older children versus neonates were 1.18 (95% CI 1.08-1.30; P<.001), 1.20 (95% CI 1.08-1.32; P=.001), 0.66 (95% CI 0.59-0.73; P<.001), and 0.20 (95% CI 0.17-0.24; P<.001), respectively. Among all broad CA groups, circulatory system malformations, mainly deaths caused by congenital heart diseases, accounted for 49.4% (866/1753) of deaths and ranked first across all years, although it declined yearly with an AACR of –9.8% (P<.001). Deaths due to chromosomal abnormalities tended to grow in recent years, although the AACR was not significant (P=.90).

Conclusions
CAMR reduced annually, with cardiovascular malformations ranking first across all years in Zhejiang, China. Future research and practices should focus more on the prevention, early detection, long-term management of CAs and comprehensive support for families with children with CAs to improve their survival chances.