bluuebunny/crossref_metadata_2025_split huggingface dataset:
Poetry and prose: the theme of exile in Nabokov's work
Authors: Тянь Ц. 
Published: June 2024

в данной статье рассматривается тема изгнания в творчестве выдающегося русско-американского писателя Владимира Набокова (1899-1977), нашедшая отражение как в его поэзии, так и в прозе. Набоков, будучи вынужденным покинуть Россию в 1919 году в возрасте 20 лет, провел большую часть своей жизни в эмиграции, что оказало значительное влияние на его мировоззрение и художественное творчество. Целью исследования является анализ мотива изгнания в поэтических и прозаических произведениях Набокова, выявление его специфики и эволюции на протяжении творческого пути писателя. Материалом для исследования послужили как ранние стихотворения Набокова, созданные в 1920-1930-е годы, так и зрелая проза, включая романы «Машенька» (1926), «Защита Лужина» (1930), «Приглашение на казнь» (1938), «Другие берега» (1954) и др. В работе применяются методы сравнительно-исторического, биографического и мотивного анализа. В результате проведенного исследования установлено, что тема изгнания является сквозной в творчестве Набокова и претерпевает определенную трансформацию: если в ранней поэзии доминирует ностальгия по утраченной родине и трагическое мироощущение, то в зрелой прозе писатель переосмысливает изгнание как возможность обретения творческой свободы и новых художественных форм. При этом Набоков виртуозно использует язык для передачи опыта изгнания, прибегая к сложным метафорам, аллюзиям и языковой игре. Полученные результаты вносят вклад в изучение творчества Набокова и расширяют представление о роли темы изгнания в его художественном наследии.
this article examines the theme of exile in the work of the outstanding Russian-American writer Vladimir Nabokov (1899-1977), reflected both in his poetry and in his prose. Nabokov, having been forced to leave Russia in 1919 at the age of 20, spent most of his life in exile, which had a significant impact on his worldview and artistic creativity. The purpose of the study is to analyze the motive of exile in Nabokov's poetic and prose works, to identify its specifics and evolution throughout the writer's creative path. The material for the study was both Nabokov's early poems, created in the 1920s and 1930s, and mature prose, including the novels "Masha" (1926), "The Defense of Luzhin" (1930), "Invitation to Execution" (1938), "Other Shores" (1954), etc. The methods of comparative historical, biographical and motivic analysis are used in the work. As a result of the conducted research, it was found that the theme of exile is end-to-end in Nabokov's work and undergoes a certain transformation: if nostalgia for the lost homeland and a tragic worldview dominate in early poetry, then in mature prose the writer rethinks exile as an opportunity to gain creative freedom and new artistic forms. At the same time, Nabokov masterfully uses language to convey the experience of exile, resorting to complex metaphors, allusions and language play. The results obtained contribute to the study of Nabokov's work and expand the understanding of the role of the theme of exile in his artistic heritage.
Taxonomy of the ant genera Leptothorax Mayr, 1855 and Temnothorax Mayr, 1861 (Hymenoptera: Formicidae) of China with descriptions of twenty-eight new species and a key to the known Chinese species
Authors: Qian Yu-Han , Xu Zheng-Hui 
Published: June 2024

The Chinese members of the genera Leptothorax Mayr, 1855 and Temnothorax Mayr, 1861 are reviewed based on the morphological characters of the worker caste, and 66 species are recognized in China to date. A new synonym is proposed: T. opaciabdomin (Chang &#38; He, 2001) is a junior synonym of T. mongolicus (Pisarski, 1969). Twenty-eight new species of Temnothorax, T. bailu sp. nov., T. chun sp. nov., T. chunfen sp. nov., T. chushu sp. nov., T. dahan sp. nov., T. dashu sp. nov., T. daxue sp. nov., T. dong sp. nov., T. dongzhi sp. nov., T. guyu sp. nov., T. hanlu sp. nov., T. jingzhe sp. nov., T. lichun sp. nov., T. lidong sp. nov., T. liqiu sp. nov., T. lixia sp. nov., T. mangzhong sp. nov., T. qingming sp. nov., T. qiu sp. nov., T. qiufen sp. nov.,T. shuangjiang sp. nov., T. xia sp. nov., T. xiaohan sp. nov., T. xiaoman sp. nov., T. xiaoshu sp. nov., T. xiaoxue sp. nov., T. xiazhi sp. nov., T. yushui sp. nov., are described from China based on worker caste. Three species of Temnothorax, T. desioi (Menozzi, 1939), T. susamyri (Dlussky, 1965) and T. volgensis (Ruzsky, 1905) are recorded in China for the first time. The following eight species are recorded in a province or autonomous region of China for the first time: Leptothorax acervorum (Fabricius, 1793) is a new record in Qinghai, Sichuan and Yunnan; Temnothorax angulohumerus Zhou et al., 2010 is a new record in Guizhou and Tibet; T. argentipes (Wheeler, 1928) is a new record in Sichuan and Yunnan; T. mongolicus (Pisarski, 1969) is a new record in Inner Mongolia; T. reticulatus (Chang &#38; He, 2001) is a new record in Beijing, Gansu, Inner Mongolia, Jilin, Shaanxi and Yunnan; T. spinosior (Forel, 1901) is a new record in Yunnan; T. taivanensis (Wheeler, 1929) is a new record in Guizhou, Sichuan and Yunnan; and T. zhejiangensis Zhou et al., 2010 is a new record in Henan and Guangxi. A key based on the worker caste is provided for the 66 known Chinese species.
Quick pix of ‘Jimbo’, the Wyoming <i>Supersaurus</i>
Authors: Wedel Matt 
Published: June 2024

Another quick photo post from the road. The Tate Museum has a quality in common with the Oxford Museum of Natural History, where the guiding philosophy seems to have been, “Let’s put one of every interesting thing in the world in one big room.” Tucked into a corner is this small assemblage of cast bits of ‘Jimbo’, the Wyoming
<em>
Supersaurus
</em>
specimen described by Lovelace et al. (2008). Here’s a tibia. And a dorsal vertebra.
MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN THAY ĐỔI CÁC CHỈ SỐ HUYẾT HỌC, SINH HÓA Ở BỆNH NHÂN UNG THƯ DẠ DÀY DI CĂN, ĐIỀU TRỊ HÓA CHẤT PHÁC ĐỒ SOX
Authors: Trần Thị Phương Thảo  , Nguyễn Trọng Hòa  , La Vân Trường  
Published: June 2024

Mục tiêu: Nghiên cứu một số yếu tố liên quan đến sự thay đổi các chỉ số huyết học, sinh hóa ở bệnh nhân ung thư dạ dày di căn, điều trị hóa chất bằng phác đồ SOX.
Đối tượng và phương pháp: Nghiên cứu hồi cứu kết hợp tiến cứu ở 62 bệnh nhân ung thư dạ dày di căn, điều trị hóa chất phác đồ SOX, tại Bệnh viện Trung ương Quân đội 108 từ tháng 4/2019-4/2023. Xét nghiệm công thức máu và chức năng gan, thận, điện giải của bệnh nhân thực hiện trước mỗi chu kì điều trị hóa chất. Đánh giá thay đổi các chỉ số theo tiêu chuẩn đánh giá các tác dụng không mong muốn thường gặp (Common Terminology Criteria for Adverse Events, version 3.0.).
Kết quả: Thay đổi chỉ số huyết học ghi nhận: giảm bạch cầu (32,3%), giảm bạch cầu hạt (32,3%), thiếu máu (85,5%), giảm tiểu cầu (24,2%). Thay đổi các chỉ số sinh hóa ghi nhận: tăng Aspartate transaminase (64,5%), tăng Alanine transaminase (33,8%), tăng bilirubin toàn phần (35,5%) và hạ natri máu (50%). Các thay đổi chỉ số huyết học chủ yếu là độ 1 và độ 2. Giảm bạch cầu và giảm bạch cầu hạt thường gặp ở các bệnh nhân có số lượng tế bào tủy thấp (p < 0,001). Thiếu máu hay gặp ở bệnh nhân không phẫu thuật cắt bỏ khối u dạ dày nguyên phát (p = 0,033). Tăng bilirubin hay gặp ở các bệnh nhân có di căn phúc mạc (p = 0,034) và di căn gan (p= 0,004). Hạ natri máu hay gặp ở các bệnh nhân có số lượng tế bào tủy thấp (p = 0,026), di căn gan (p = 0,038) và không phẫu thuật cắt bỏ khối u dạ dày nguyên phát (p = 0,041).
In Vitro Transcription and Immobilized Template Analysis of Preinitiation Complexes
Authors: Lin Justin J. , Carey Michael 
Published: January 2012

AbstractIn the study of gene regulation, it is often necessary to employ functional assays that investigate the action or mechanism of specific promoters or enhancer‐binding factors and their role in transcription by RNA polymerase II. Although many assays measure the transcription of a gene under the control of an endogenous or model activator in vivo, it is often useful to recreate transcription in vitro in order to study specific regulatory mechanisms. In this unit, protocols are presented that will allow the investigator to perform in vitro transcription using preinitiation complexes assembled from cellular extracts on either naked DNA or chromatin templates. Curr. Protoc. Mol. Biol. 97:12.14.1‐12.14.19. © 2012 by John Wiley & Sons, Inc.
Protein Databases on the Internet
Authors: Xu Dong 
Published: January 2012

AbstractProtein databases have become a crucial part of modern biology. Huge amounts of data for protein structures, functions, and particularly sequences are being generated. Searching databases is often the first step in the study of a new protein. Comparison between proteins or between protein families provides information about the relationship between proteins within a genome or across different species, and hence offers much more information than can be obtained by studying only an isolated protein. In addition, secondary databases derived from experimental databases are also widely available. These databases reorganize and annotate the data or provide predictions. The use of multiple databases often helps researchers understand the structure and function of a protein. Although some protein databases are widely known, they are far from being fully utilized in the protein science community. This unit provides a starting point for readers to explore the potential of protein databases on the Internet. Curr. Protoc. Mol. Biol. 97:19.4.1‐19.4.17. © 2012 by John Wiley & Sons, Inc.
Hexylthiophene‐Featured D–A–π–A Structural Indoline Chromophores for Coadsorbent‐Free and Panchromatic Dye‐Sensitized Solar Cells
Authors: Wu Yongzhen , Zhang Xi , Li Wenqin , Wang Zhong‐Sheng , Tian He , Zhu Weihong 
Published: January 2012

AbstractFor a sensitizer with a strong π‐conjugation system, a coadsorbent is needed to hinder dye aggregation. However, coadsorption always brings a decrease in dye coverage on the TiO2 surface. Organic ‘‘D–A–π–A’’ dyes, WS‐6 and WS‐11, are designed and synthesized based on the known WS‐2 material for coadsorbent‐free, dye‐sensitized solar cells (DSSCs). Compared with the traditional D–π–A structure, these D–A–π–A indoline dyes, with the additional incorporated acceptor unit of benzothiadiazole in the π‐conjugation, exhibit a broad photoresponse, high redox stability, and convenient energy‐level tuning. The attached n‐hexyl chains in both dyes are effective to suppress charge recombination, resulting in a decreased dark current and enhanced open‐circuit voltage. Electrochemical impedance spectroscopy studies indicate that both the resistance for charge recombination and the electron lifetime are increased after the introduction of alkyl chains to the dye molecules. Without deoxycholic acid coadsorption, the power‐conversion efficiency of WS‐6 (7.76%) on a 16 μm‐thick TiO2 film device is 45% higher than that of WS‐2 (5.31%) under the same conditions. The additional n‐hexylthiophene in WS‐11 extends the photoresponse to a panchromatic spectrum but causes a low incident photon‐to‐current conversion efficiency.
Mantle cell lymphoma displays a homogenous methylation profile: A comparative analysis with chronic lymphocytic leukemia
Authors: Halldórsdóttir Anna Margrét , Kanduri Meena , Marincevic Millaray , Mansouri Larry , Isaksson Anders , Göransson Hanna , Axelsson Tomas , Agarwal Prasoon , Jernberg‐Wiklund Helena , Stamatopoulos Kostas , Sander Birgitta , Ehrencrona Hans , Rosenquist Richard 
Published: January 2012

AbstractMantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) are mature CD5+ B‐cell malignancies with different biological/clinical characteristics. We recently reported an association between different prognostic subgroups of CLL (i.e., IGHV mutated and unmutated) and genomic methylation pattern. However, the relationship between DNA methylation and prognostic markers, such as the proliferation gene expression signature, has not been investigated in MCL. We applied high‐resolution methylation microarrays (27,578 CpG sites) to assess the global DNA methylation profiles in 20 MCL (10 each with high/low proliferation signature) and 30 CLL (15 poor‐prognostic IGHV unmutated subset #1 and 15 good‐prognostic IGHV mutated subset #4) samples. Notably, MCL and each CLL subset displayed distinct genomic methylation profiles. After unsupervised hierarchical clustering, 17/20 MCL cases formed a cluster separate from CLL, while CLL subsets #1 and #4 formed subclusters. Surprisingly, few differentially methylated genes (n = 6) were identified between high vs. low proliferation MCL. In contrast, distinct methylation profiles were demonstrated for MCL and CLL. Importantly, certain functional classes of genes were preferentially methylated in either disease. For instance, developmental genes, in particular homeobox transcription factor genes (e.g., HLXB9, HOXA13), were more highly methylated in MCL, whereas apoptosis‐related genes were enriched among targets methylated in CLL (e.g., CYFIP2, NR4A1). Results were validated using pyrosequencing, RQ‐PCR and reexpression of specific genes. In summary, the methylation profile of MCL was homogeneous and no correlation with the proliferation signature was observed. Compared to CLL, however, marked differences were discovered such as the preferential methylation of homeobox genes in MCL. Am. J. Hematol., 2012. © 2012 Wiley Periodicals, Inc.
Lung cancer risk among construction workers in California, 1988–2007
Authors: Calvert Geoffrey M. , Luckhaupt Sara , Lee Soo‐Jeong , Cress Rosemary , Schumacher Pam , Shen Rui , Tak SangWoo , Deapen Dennis 
Published: January 2012

AbstractBackgroundAlthough lung cancer risks can vary by race/ethnicity and by construction occupation, these risks have not been examined extensively.MethodsThis study analyzed 110,937 lung cancer cases identified from the California Cancer Registry between 1988 and 2007. Mean age at diagnosis, proportion diagnosed at an advanced stage, and proportion with 3‐year survival were calculated for lung cancer cases employed in the construction industry. Case–control methodology was also used to assess the risk of lung cancer. Morbidity odds ratios (MORs) were estimated by conditional logistic regression.ResultsConstruction workers were found to have a significantly elevated risk for all lung cancer combined (MOR = 1.57) and for each lung cancer histologic subtype examined. All construction occupations, except managers/engineers and supervisors, had a significantly elevated risk for all lung cancer combined. Roofers and welders had the highest risks for total lung cancer and for each of the histologic subtypes. Construction workers in each of the four race/ethnicity groups also had significantly increased lung cancer risks. Compared to non‐construction workers, construction workers were diagnosed at an earlier age, at a more advanced stage, and had significantly lower 3‐year survival, though differences were modest.ConclusionThese findings justify additional reductions in carcinogenic exposures in construction, and increased support for smoking cessation programs at construction sites. Am. J. Ind. Med. 55:412–422, 2012. © 2012 Wiley Periodicals, Inc.
Migrant farmworker housing regulation violations in north Carolina
Authors: Arcury Thomas A. , Weir Maria , Chen Haiying , Summers Phillip , Pelletier Lori E. , Galván Leonardo , Bischoff Werner E. , Mirabelli Maria C. , Quandt Sara A. 
Published: January 2012

AbstractBackgroundThe quality of housing provided to migrant farmworkers is often criticized, but few studies have investigated these housing conditions. This analysis examines housing regulation violations experienced by migrant farmworkers in North Carolina, and the associations of camp characteristics with the presence of housing violations.MethodsData were collected in183 eastern North Carolina migrant farmworker camps in 2010. Housing regulation violations for the domains of camp, sleeping room, bathroom, kitchen, laundry room, and general housing, as well as total violations were assessed using North Carolina Department of Labor standards.ResultsViolations of housing regulations were common, ranging from 4 to 22 per camp. Housing regulation violations were common in all domains; the mean number of camp violations was 1.6, of sleeping room violations was 3.8, of bathroom violations was 4.5, of kitchen violations was 2.3, of laundry room violations was 1.2, and of general housing violations was 3.1. The mean number of total housing violations was 11.4. Several camp characteristics were consistently associated with the number of violations; camps with workers having H‐2A visas, with North Carolina Department of Labor Certificates of Inspection posted, and assessed early in the season had fewer violations.ConclusionsThese results argue for regulatory changes to improve the quality of housing provided to migrant farmworkers, including stronger regulations and the more vigorous enforcement of existing regulations. Am. J. Ind. Med. 55:191–204, 2012. © 2011 Wiley Periodicals, Inc.
Occupational contact allergens: Are they also associated with occupational asthma?
Authors: Arrandale V.H. , Liss G.M. , Tarlo S.M. , Pratt M.D. , Sasseville D. , Kudla I. , Holness D.L. 
Published: January 2012

AbstractBackgroundWorkplace exposures that can potentially cause both allergic occupational contact dermatitis (AOCD) and occupational asthma (OA) are not clearly identified.MethodsOccupational contact allergens (OCAs) were identified using North American Contact Dermatitis Group (NACDG) data. Reference documents and systematic reviews were used to determine whether each OCA had been reported to potentially cause OA. The presence or absence of a sensitizer notation in occupational hygiene reference documents was also examined.ResultsThe 10 most common OCAs were: epoxy resin*, thiuram, carba mix, nickel sulfate*, cobalt chloride*, potassium dichromate*, glyceryl thioglycolate, p‐phenylenediamine*, formaldehyde* and glutaraldehyde*. Seven (indicated by *) were determined to be possible causes of OA. Information on sensitizing potential from OH reference materials contained conflicting information.ConclusionsSeveral common OCAs can also potentially cause OA. Inhalation and dermal exposures to these agents should be controlled and both OA and AOCD should be considered as possible health outcomes. Increased consistency in sensitizer notations is needed. Am. J. Ind. Med. 55:353–360, 2012. © 2011 Wiley Periodicals, Inc.
Increased IgG on cell‐derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation
Authors: Nielsen Christoffer T. , Østergaard Ole , Stener Line , Iversen Line V. , Truedsson Lennart , Gullstrand Birgitta , Jacobsen Søren , Heegaard Niels H. H. 
Published: January 2012

AbstractObjectiveTo quantify immunoglobulin and C1q on circulating cell‐derived microparticles (MPs) in patients with systemic lupus erythematosus (SLE) and to determine whether immunoglobulin and C1q levels are correlated with clinical and serologic parameters.MethodsSixty‐eight clinically well‐characterized SLE patients, 38 healthy controls, 6 patients with systemic sclerosis (SSc), and 6 patients with rheumatoid arthritis (RA) were included. The numbers of annexin V–binding MPs displaying IgG, IgM, or C1q were enumerated by flow cytometry. MP protein levels were determined by mass spectrometry in clinically defined subsets of SLE patients and controls. The MP IgG load was determined by flow cytometric analysis of all samples from SLE patients and healthy controls.ResultsSLE patients had significantly increased total and relative numbers of IgG‐positive MPs (P= 0.0004), with a much higher average IgG load per MP (P< 0.0001) than healthy controls. Quantitative mass spectrometry of purified MPs verified significantly increased IgG, IgM, and C1q levels in SLE patients. In RA and SSc patients, the average IgG load per MP was significantly lower than in SLE patients (P= 0.006 andP= 0.05, respectively). Also, the IgM load and C1q load per MP were significantly higher in SLE patients than in the control groups (P< 0.05), except for IgM in the RA group. IgG‐positive MPs were significantly associated with the presence of anti–double‐stranded DNA, anti–extractable nuclear antigen, and antihistone antibodies, with total IgG, and with decreased leukocyte counts. Average IgG load per MP was associated with lower concentrations of MPs, the presence of anti‐C1q antibodies, and complement consumption.ConclusionOur findings indicate that circulating cell‐derived MPs in SLE patients carry increased loads of IgG, IgM, and C1q and that IgG MPs are associated with autoantibodies and complement activation. The findings link immunologic reactions on MPs with the etiology of SLE.
Molecular bioelectricity in developmental biology: New tools and recent discoveries
Authors: Levin Michael 
Published: January 2012

AbstractSignificant progress in the molecular investigation of endogenous bioelectric signals during pattern formation in growing tissues has been enabled by recently developed techniques. Ion flows and voltage gradients produced by ion channels and pumps are key regulators of cell proliferation, migration, and differentiation. Now, instructive roles for bioelectrical gradients in embryogenesis, regeneration, and neoplasm are being revealed through the use of fluorescent voltage reporters and functional experiments using well‐characterized channel mutants. Transmembrane voltage gradients (Vmem) determine anatomical polarity and function as master regulators during appendage regeneration and embryonic left‐right patterning. A state‐of‐the‐art recent study reveals that they can also serve as prepatterns for gene expression domains during craniofacial patterning. Continued development of novel tools and better ways to think about physical controls of cell‐cell interactions will lead to mastery of the morphogenetic information stored in physiological networks. This will enable fundamental advances in basic understanding of growth and form, as well as transformative biomedical applications in regenerative medicine.
Assessing Metal–Metal Multiple Bonds in CrCr, MoMo, and WW Compounds and a Hypothetical UU Compound: A Quantum Chemical Study Comparing DFT and Multireference Methods
Authors: Li Manni Giovanni , Dzubak Allison L. , Mulla Abbas , Brogden David W. , Berry John F. , Gagliardi Laura 
Published: January 2012

AbstractTo gain insights into the trends in metal–metal multiple bonding among the Group 6 elements, density functional theory has been employed in combination with multiconfigurational methods (CASSCF and CASPT2) to investigate a selection of bimetallic, multiply bonded compounds. For the compound [Ar‐MM‐Ar] (Ar=2,6‐(C6H5)2‐C6H3, M=Cr, Mo, W) the effect of the Ar ligand on the M2 core has been compared with the analogous [Ph‐MM‐Ph] (Ph=phenyl, M=Cr, Mo, W) compounds. A set of [M2(dpa)4] (dpa=2,2′‐dipyridylamide, M=Cr, Mo, W, U) compounds has also been investigated. All of the compounds studied here show important multiconfigurational behavior. For the Mo2 and W2 compounds, the σ2π4δ2 configuration dominates the ground‐state wavefunction, contributing at least 75 %. The Cr2 compounds show a more nuanced electronic structure, with many configurations contributing to the ground state. For the Cr, Mo, and W compounds the electronic absorption spectra have been studied, combining density functional theory and multireference methods to make absorption feature assignments. In all cases, the main features observed in the visible spectra may be assigned as charge‐transfer bands. For all compounds investigated the Mayer bond order (MBO) and the effective bond order (EBO) were calculated by density functional theory and CASSCF methods, respectively. The MBO and EBO values share a similar trend toward higher values at shorter normalized metal–metal bond lengths.