bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of SARS-CoV-2 antibodies and associated factors in the adult population of Belgium: a general population cohort study between March 2021 and April 2022
Authors: Van der Heyden Johan , Leclercq Victoria , Duysburgh Els , Cornelissen Laura , Desombere Isabelle , Roukaerts Inge , Gisle Lydia 
Published: May 2024

Abstract
Background
This study assessed seroprevalence trends of SARS-CoV-2 antibodies in the Belgian adult population between March 2021 and April 2022, and explored factors associated with seropositivity and seroreversion among the vaccinated and unvaccinated population.

Methods
A prospective longitudinal surveillance study was conducted within a random sample of the general population (18 + years) in Belgium, selected from the national register through a multistage sampling design. Participants provided a saliva sample and completed a survey questionnaire on three occasions: at baseline and in two follow-up waves. Outcome variables included (1) seropositivity, defined as the presence of SARS-CoV-2 antibodies, assessed with a semi-quantitative measure of anti-RBD (Receptor Binding Domain) IgG ELISA and (2) seroreversion, defined as passing from a positive to a negative antibody test between two measurements. Trends in SARS-CoV-2 antibody prevalence were assessed using binary logistic regression with contrasts applying post-stratification. Potential determinants of seropositivity were assessed through multilevel logistic regressions.

Results
In total 6,178 valid observations were obtained from 2,768 individuals. SARS-CoV-2 antibody prevalence increased from 25.1% in the beginning of the study period to 92.3% at the end. Among the vaccinated population, factors significantly associated with higher seropositivity rates were being younger, having a bachelor diploma, living with others, having had a vaccine in the last 3 months and having received a nucleic-acid vaccine or a combination. Lower seropositivity rates were observed among vaccinated people with a neurological disease and transplant patients. Factors significantly associated with higher seropositivity rates among the unvaccinated population were having non-O blood type and being non-smoker. Among vaccinated people, the seroreversion rate was much lower (0.3%) in those who had received their latest vaccine in the last 3 months compared to those who had received their latest vaccine more than 3 months ago (2.7%) (OR 0.13; 95%CI 0.04–0.42).

Conclusions
The rapid increase in antibody seropositivity in the general adult population in Belgium during the study period was driven by the vaccination campaign which ran at full speed during this period. Among vaccinated people, seropositivity varied in function of the time since last vaccine, the type of vaccine, sociodemographic features and health status.
Comparison of angiographic change in side-branch ostium after drug-coated balloon vs. drug-eluting stent vs. medication for the treatment of de novo coronary bifurcation lesions
Authors: Her Ae-Young , Kim Bitna , Kim Sunwon , Kim Yong Hoon , Scheller Bruno , Shin Eun-Seok 
Published: May 2024

Abstract
Objectives
Data on side-branch (SB) ostial effect after drug-coated balloon (DCB) treatment in the context of de novo coronary bifurcation lesions are limited. We aimed to investigate the angiographic outcomes of SB ostium after DCB treatment compared with drug-eluting stents (DESs) implantation in the main vessel (MV) or optimal medical therapy (OMT) for the treatment of de novo coronary bifurcation lesions.

Methods
Serial angiographic changes in the SB ostium were compared between DCB, DES, and medication alone for MV treatment. Δ value was calculated by subtracting the follow-up value from the pre-procedure value.

Results
A total of 132 bifurcation lesions were included for analysis (44 lesions in DCB group; 38 lesions in DES group; 50 lesions in OMT group). The minimal lumen diameter (MLD) of SB ostium showed an increase at follow-up in the DCB group, whereas a decrease was observed in both the DES and OMT groups (ΔMLD: −0.16 ± 0.45 mm for DCB group vs. 0.50 ± 0.52 mm for DES group vs. 0.08 ± 0.38 mm for OMT group, p < 0.001). The diameter stenosis (DS) of SB ostium showed a marked decrease at follow-up in the DCB group, in contrast to an increase observed in both the DES and OMT groups (ΔDS: 8.01 ± 18.96% for DCB group vs. −18.68 ± 18.60% for DES group vs. −2.05 ± 14.58% for OMT group, p < 0.001).

Conclusions
In de novo coronary bifurcation lesions, DCB treatment on the MV demonstrated favorable angiographic outcomes in the SB ostium at 6–9 month follow-up compared to DES implantation or OMT.
Skyline query under multidimensional incomplete data based on classification tree
Authors: Yuan Dengke , Zhang Liping , Li Song , Sun Guanglu 
Published: May 2024

AbstractA method for skyline query of multidimensional incomplete data based on a classification tree has been proposed to address the problem of a large amount of useless data in existing skyline queries with multidimensional incomplete data, which leads to low query efficiency and algorithm performance. This method consists of two main parts. The first part is the proposed incomplete data weighted classification tree algorithm. In the first part, an incomplete data weighted classification tree is proposed, and the incomplete data set is classified using this tree. The data classified in the first part serves as the basis for the second step of the query. The second part proposes a skyline query algorithm for multidimensional incomplete data. The concept of optimal virtual points has been recently introduced, effectively reducing the number of comparisons of a large amount of data, thereby improving the query efficiency for incomplete data. Theoretical research and experimental analysis have shown that the proposed method can perform skyline queries for multidimensional incomplete data well, with high query efficiency and accuracy of the algorithm.
The impact of changing engineering perceptions on women’s attitudes and behavioral intentions towards engineering pursuits
Authors: Batz-Barbarich Cassondra , Strah Nicole , Tay Louis 
Published: May 2024

Abstract
Background
Women are underrepresented in the field of engineering within academic and professional settings. Based upon premises outlined by social role theory and goal congruity theory, a key factor that contributes to this underrepresentation is a gendered societal belief that there is a disconnect between engineering (seen as more agentic, or self-oriented) and women’s values and abilities (which are believed to be more communal, or other-oriented). While there is evidence that this perceived disconnect influences women’s pursuit of engineering, the extent to which an intervention could realistically counter these perceptions at key points along the engineering pathway has not been explored. Across two studies, we examine the impact of a communal-based intervention (in which we frame engineering majors and careers in more, though not exclusively, communally oriented ways) on women’s engineering-related attitudes and behavioral intentions at two points along the academic-employment pathway: women’s major selection and women’s job selection.

Results
Study 1 found that women with undeclared majors had more positive attitudes (confidence and interest) towards engineering majors when engineering major descriptions were framed as more communal versus more agentic. However, there was no impact on their behavioral intentions to pursue the major. Study 2 found that women with engineering majors were more confident in their ability to be successful in a job role and were more likely to apply when the job role was framed as more communal as compared to more agentic. However, they did not indicate greater interest in the job role.

Conclusions
Testing this intervention on relevant populations advances the literature by providing greater evidence for the potential of such an intervention to meaningfully address women’s underrepresentation at multiple points along the engineering pathway. Furthermore, this study provides evidence that a messaging-based intervention is impactful with a realistic representation of engineering as both an agentic and communally oriented field, which ensures that the retention of those attracted to the field is not negatively impacted by idealistic messaging. While addressing women’s pursuit of engineering is important, work must continue to seek ways to always improve women’s experience in engineering contexts as well.
Thick slab crust with rough basement weakens interplate coupling in the western Nankai Trough
Authors: Arai Ryuta , Shiraishi Kazuya , Nakamura Yasuyuki , Fujie Gou , Miura Seiichi , Kodaira Shuichi , Bassett Dan , Takahashi Tsutomu , Kaiho Yuka , Hamada Yohei , Mochizuki Kimihiro , Nakata Rie , Kinoshita Masataka , Hashimoto Yoshitaka , Okino Kyoko 
Published: May 2024

AbstractThe westernmost Nankai Trough, southwest Japan, exhibits a rapid along-strike reduction in plate coupling in the proximity to the subducting Kyushu-Palau ridge. Yet how and to what extent the ridge subduction impacts physical properties at the megathrust have not been investigated. Here we present high-resolution seismic P-wave velocity models along the forearc wedge in the western Nankai Trough derived from full-waveform inversion analyses of seismic refraction data. The velocity models show that where the plate coupling is weak and the plate boundary presumably hosts slow earthquakes, the upper plate exhibits lower seismic velocities indicating higher degree of fracturing over a ~ 100 km length along trough. Intriguingly, the extent of the upper-plate low-velocity features is significantly larger than the surficial width of the Kyushu-Palau ridge, and this low-velocity zone is underthrust by the slab with increased crustal thickness by 2–4 km. Seismic reflection images consistently reveal that the thicker slab crust has appreciable basement roughness extending ~ 60 km from the eastern margin of the Kyushu-Palau ridge beneath the western Shikoku basin. We suggest that such a thicker and rugged slab crust, together with the main body of the Kyushu-Palau ridge, can cause significant fracture zones in the overriding plate, decrease the interplate coupling and produce preferable conditions for shallow slow earthquakes to occur when subducted. The results may also provide structural constraints on the western limit of future megathrust earthquakes in the Nankai Trough.
Graphical Abstract
Stage IV gastric adenocarcinoma with enteroblastic differentiation with 5-year relapse-free survival after D2 gastrectomy and chemotherapy: A case report
Authors: Nakayama Hiroshi , Ida Tomonori , Hasegawa Yui , Sakamoto Atsuhiko , Umezawa Yoko , Inaba Yuki , Nakada Hiroshi 
Published: May 2024

Abstract
Background
Gastric adenocarcinoma with enteroblastic differentiation (GACED), a rare subtype of gastric cancer, is associated with a more aggressive behavior than conventional gastric adenocarcinomas. We report a rare case of stage IV GACED treated with D2 gastrectomy and postoperative chemotherapy.

Case presentation
A 39-year-old woman with acute upper abdominal pain immediately underwent surgery for gastric perforation. Afterward she was diagnosed with adenocarcinoma of the pylorus. D2 gastrectomy was performed and the final pathological diagnosis was stage IV GACED with positive peritoneal cytology. Postoperative chemotherapy was initiated with S1 plus oxaliplatin for 1 year, which was ceased thereafter to enhance her quality of life. The patient survived more than 5 years without relapse after gastrectomy.

Conclusions
Stage IV GACED, determined by positive spalt-like transcription factor 4, can be successfully treated with surgery and chemotherapy.
Physical and Psychosocial Benefits of Sports Participation Among Children and Adolescents with Chronic Diseases: A Systematic Review
Authors: Sañudo Borja , Sánchez-Oliver Antonio Jesús , Fernández-Gavira Jesús , Gaser Dominik , Stöcker Nicola , Peralta Miguel , Marques Adilson , Papakonstantinou Sofia , Nicolini Chiara , Sitzberger Christina 
Published: May 2024

Abstract
Background
This study aims to identify sports interventions for children and adolescents (CaA) with chronic diseases and evaluate their impact on physical, psychological, and social well-being. The findings of this study will contribute to our understanding of the potential benefits of sports interventions for CaA with chronic diseases and inform future interventions to promote their overall health and well-being.

Methods
A systematic review was conducted in eight databases. This systematic review followed PRISMA guidelines and utilized a comprehensive search strategy to identify studies on sport-based interventions for CaA with chronic diseases. The review included randomized controlled trials and observational studies that focused on physical and psychosocial outcomes.

Results
We screened 10,123 titles and abstracts, reviewed the full text of 622 records, and included 52 primary studies. A total of 2352 participants were assessed with an average of 45 ± 37 participants per study. Among the included studies involving CaA with chronic diseases with an age range from 3 to 18 years, 30% (n = 15) autism spectrum disorders, 21% (n = 11) cerebral palsy, 19% (n = 10) were attention deficit hyperactivity disorder, and 17% (n = 9) obesity. Other diseases included were cancer (n = 5), asthma (n = 1) and cystic fibrosis (n = 1). Interventions involved various sports and physical activities tailored to each chronic disease. The duration and frequency of interventions varied across studies. Most studies assessed physical outcomes, including motor performance and physical fitness measures. Psychosocial outcomes were also evaluated, focusing on behavioural problems, social competencies, and health-related quality of life.

Conclusion
Overall, sport-based interventions effectively improved physical and psychosocial outcomes in CaA with chronic diseases. Interventions are generally safe, and participants adhere to the prescribed protocols favorably. Despite that, there is little evidence that interventions are being implemented. Future studies should include interventions tailored to meet the common issues experienced by CaA with chronic conditions, providing a comprehensive understanding of the impact of sports interventions on those affected.

Registration

The methodology for this review was pre-determined and registered in the PROSPERO database (registration number: CRD42023397172).
Assessing donor-recipient arterial pressure dynamics in STA-MCA bypass for moyamoya disease
Authors: Helmy Mohamed , Liao Yujun , Zhao Zehao , Li Zhiqi , He Kangmin , Xu Bin 
Published: May 2024

Abstract
Background
In bypass surgery for moyamoya disease (MMD), the superficial temporal artery’s (STA) pressure needs to surpass that of the cortical M4 recipient of the middle cerebral artery (MCA), boosting cerebral blood flow into the MCA and enhancing cerebral circulation. This study investigates the STA-MCA arterial pressure parameters and gradients during bypass surgery, aiming to deepen our understanding of hemodynamic shifts pre- and post-operation.

Methods
DSA imaging data were prospectively collected from patients diagnosed with bilateral MMD who underwent STA-MCA bypass surgery between 2022 and 2023 and stratified according to the Suzuki stage. The mean arterial pressure (MAP) of the donor and recipient arteries was directly measured during the STA-MCA bypass procedure, and these data were statistically analyzed and evaluated.

Results
Among 48 MMD patients, Suzuki grading revealed that 43.8% were in early stages (II and III), while 56.2% were in advanced stages (IV, V, and VI). Predominantly, 77.1% presented with ischemic-type MMD and 22.9% with hemorrhagic type. Pre-bypass assessments showed that 62.5% exhibited antegrade blood flow direction, and 37.5% had retrograde. The mean recipient artery pressure was 35.0 ± 2.3 mmHg, with a mean donor-recipient pressure gradient (δP) of 46.4 ± 2.5 mmHg between donor and recipient arteries. Post-bypass, mean recipient artery pressure increased to 73.3 ± 1.6 mmHg. No significant correlation (r = 0.18, P = 0.21) was noted between δP and Suzuki staging.

Conclusion
Our study elucidated that cerebral blood pressure significantly decreases beyond the moyamoya network at the distal M4 segment. Furthermore, we observed bidirectional flow in MCA territories and a significant positive pressure gradient between the STA and M4 segments. The lack of correlation between Suzuki stages and M4 pressures indicates that angiographic severity may not reflect hemodynamic conditions before surgery, highlighting the need for customized surgical approaches.
Are psychosocial interventions effective in reducing antipsychotic use for dementia in care home residents? Current evidence and future perspectives
Authors: Chen Jiaying 
Published: May 2024

SUMMARYAntipsychotics are commonly prescribed to manage the behavioural and psychological symptoms of dementia (BPSD) despite their modest efficacy and significant adverse effects. Psychosocial interventions are recommended as the first-line approach in treating BPSD before considering pharmacological options. A Cochrane Review by Lühnen et al (2023) evaluated the effects of psychosocial interventions on reducing antipsychotic prescription in care homes, and found that no generalisable recommendations can be made based on the currently available evidence. This commentary attempts to critically appraise and add context to the review.
Value of Real-World Evidence for Treatment Selection: A Case Study in Colon Cancer
Authors: Shen Lingjie , van Gestel Anja , Prinsen Peter , Vink Geraldine , van Erning Felice N. , Geleijnse Gijs , Kaptein Maurits 
Published: May 2024

PURPOSE Real-world evidence (RWE)—derived from analysis of real-world data (RWD)—has the potential to guide personalized treatment decisions. However, because of potential confounding, generating valid RWE is challenging. This study demonstrates how to responsibly generate RWE for treatment decisions. We validate our approach by demonstrating that we can uncover an existing adjuvant chemotherapy (ACT) guideline for stage II and III colon cancer (CC)—which came about using both data from randomized controlled trials and expert consensus—solely using RWD. METHODS Data from the population-based Netherlands Cancer Registry from a total of 27,056 patients with stage II and III CC who underwent curative surgery were analyzed to estimate the overall survival (OS) benefit of ACT. Focusing on 5-year OS, the benefit of ACT was estimated for each patient using G-computation methods by adjusting for patient and tumor characteristics and estimated propensity score. Subsequently, on the basis of these estimates, an ACT decision tree was constructed. RESULTS The constructed decision tree corresponds to the current Dutch guideline: patients with stage III or stage II with T stage 4 should receive surgery and ACT, whereas patients with stage II with T stage 3 should only receive surgery. Interestingly, we do not find sufficient RWE to conclude against ACT for stage II with T stage 4 and microsatellite instability-high (MSI-H), a recent addition to the current guideline. CONCLUSION RWE, if used carefully, can provide a valuable addition to our construction of evidence on clinical decision making and therefore ultimately affect treatment guidelines. Next to validating the ACT decisions advised in the current Dutch guideline, this paper suggests additional attention should be paid to MSI-H in future iterations of the guideline.
Quantum entanglement between neutrino eigenstates in the presence of the subsequent phase shift of the neutrino oscillations
Authors: Abdolalizadeh Hoda , Aydiner Ekrem 
Published: May 2024

Abstract
In this letter, using von Neumann entropy we examine the entanglement entropy for the neutrino oscillations in the presence of the subsequent phase shift. We numerically show that the entanglement entropy for the subsequent periods of the two-flavor neutrino oscillations increases asymmetrically with time depending on the space-time deformation. We also explored the obtained results for the three-flavor neutrino oscillations to show that this result is also valid for the three-flavor neutrino oscillations. These results, obtained for the first time in this letter, are quite different from the computing for the standard neutrino oscillation theory. We concluded that these interesting results play an important role in the cosmology.
Platelet-rich plasma as a new treatment method in orthopedics
Authors: Janocha Aleksandra , Jerzak Aneta , Hitnarowicz Anna , Kmak Bożena , Szot Anna , Pociecha Agnieszka 
Published: May 2024

Introduction and purposePlatelet-rich plasma (PRP) therapy represents a technology designed to enhance tissue repair by locally administering one's own bioactive agents, aiming to influence physiological processes like inflammation, angiogenesis, and extracellular matrix synthesis. Recently, the use of PRP therapy has become a subject of discussion in the orthopedic field. This review comprehensively examines the mechanisms, contemporary applications, clinical evidence, safety aspects, and potential future advancements of PRP in orthopedic treatment. Research has documented the efficacy of PRP injections in achieving full regeneration and enabling a comeback to competitive sports. PRP injections could serve as a viable alternative treatment for individuals with lateral tendonitis when compared to surgery. Further research investigating the impact of PRP on the bone healing process following a fracture is warranted.
Materials and methods The methodology for conducting literature search involved utilizing medical subject headings terms to explore PubMed. Search terms included: "plasma-rich therapy", "tendinopathy", "injury" " articular cartilage ", "bone fracture "
ConclusionsResearch at different evidence levels has shown that PRP is safe and has beneficial effects in above uses. Due to the autologous nature of the therapy, side effects are minimal. In the majority of cases, PRP therapy alleviates pain sensations in both short- and long-term observations, facilitating a faster return to daily functionality. However, additional randomized, controlled clinical trials are anticipated to be conducted in the future. Progressing further necessitates the standardization of methods for preparing plasma and procedures for its application.
Matching Impatient and Heterogeneous Demand and Supply
Authors: Aveklouris Angelos , DeValve Levi , Stock Maximiliano , Ward Amy 
Published: May 2024

Balancing Speed and Value in On-Demand Matching Platforms In “Matching Impatient and Heterogeneous Demand and Supply,” Aveklouris, DeValve, Stock, and Ward consider a fundamental trade-off faced by many platforms (e.g., Uber/Lyft) that match supply (e.g., drivers) and demand (e.g., riders) dynamically over time: making matches quickly capitalizes on the value of current supply and demand in the system, whereas waiting may enable better matches at the risk of losing impatient customers. They show that this trade-off can be balanced by waiting a short amount of time before making matches: long enough to gather enough agents to make valuable matches but not so long that impatient agents are likely to leave. Intuitively, this balance depends on how long agents are willing to wait, on average, but the authors show that it also depends on the full distribution of the willingness to wait (i.e., not only mean, but also variance and higher moments play a role). Thus, approaches that only take into account the mean willingness to wait may perform quite poorly. Further, the authors develop an algorithm to rank matching priorities in order to achieve an optimized trade-off between speed and value of matches.