bluuebunny/crossref_metadata_2025_split huggingface dataset:
The multifaceted functions of long non-coding RNAHOTAIRin neuropathologies and its potential as a prognostic marker and therapeutic biotarget
Authors: Ahmad Faraz , Sudesh Ravi , Ahmed Atheeq Toufeeq , Arumugam Mohanapriya , Mathkor Darin Mansor , Haque Shafiul 
Published: April 2024

AbstractLong non-coding RNAs (lncRNAs) are progressively being perceived as prominent molecular agents controlling multiple aspects of neuronal (patho)physiology. Amongst these is the HOX transcript antisense intergenic RNA, often abbreviated asHOTAIR.HOTAIRepigenetically regulates its target genes via its interaction with two different chromatin-modifying agents; histone methyltransferase polycomb-repressive complex 2 and histone demethylase lysine-specific demethylase 1. Parenthetically,HOTAIRelicits trans-acting sponging function against multiple micro-RNA species. Oncological research studies have confirmed the pathogenic functions ofHOTAIRin multiple cancer types, such as gliomas and proposed it as a pro-oncological lncRNA. In fact, its expression has been suggested to be a predictor of the severity/grade of gliomas, and as a prognostic biomarker. Moreover, a propound influence ofHOTAIRin other aspects of brain heath and disease states is just beginning to be unravelled. The objective of this review is to recapitulate all the relevant data pertaining to the regulatory roles ofHOTAIRin neuronal (patho)physiology. To this end, we discuss the pathogenic mechanisms ofHOTAIRin multiple neuronal diseases, such as neurodegeneration, traumatic brain injury and neuropsychiatric disorders. Finally, we also summarize the results from the studies incriminatingHOTAIRin the pathogeneses of gliomas and other brain cancers. Implications ofHOTAIRserving as a suitable therapeutic target in neuropathologies are also discussed.
Compression and acceleration processes of spherical shells in gold cones
Authors: Wei Huigang , Yuan Dawei , Wang Shaojun , Cui Ye , Yang Xiaohu , Ma Yanyun , Zhang Zhe , Yuan Xiaohui , Zhong Jiayong , Hua Neng , Li Yutong , Zhu Jianqiang , Zhao Gang , Zhang Jie 
Published: April 2024

Abstract
Double-cone ignition [Zhang et al., Phil. Trans. R. Soc. A 378, 20200015 (2020)] was proposed recently as a novel path for direct-drive inertial confinement fusion using high-power lasers. In this scheme, plasma jets with both high density and high velocity are required for collisions. Here we report preliminary experimental results obtained at the Shenguang-II upgrade laser facility, employing a CHCl shell in a gold cone irradiated with a two-ramp laser pulse. The CHCl shell was pre-compressed by the first laser ramp to a density of 3.75 g/cm3 along the isentropic path. Subsequently, the target was further compressed and accelerated by the second laser ramp in the cone. According to the simulations, the plasma jet reached a density of up to 15 g/cm3, while measurements indicated a velocity of 126.8 ± 17.1 km/s. The good agreements between experimental data and simulations are documented.
Dialectometry-based classification of the Central–Southern Italian dialects
Authors: Sciarretta Antonio 
Published: April 2024

AbstractThis paper provides a new classification of Central–Southern Italian dialects using dialectometric methods. All varieties considered are analyzed and cast in a data set where homogeneous areas are evaluated according to a selected list of phonetic features. Using numerical evaluation of these features and the Manhattan distance, a linguistic distance rule is defined. On this basis, the classification problem is formulated as a clustering problem, and a k-means algorithm is used. Additionally, an ad-hoc rule is set to identify transitional areas, and silhouette analysis is used to select the most appropriate number of clusters. While meaningful results are obtained for each number of clusters, a nine-group classification emerges as the most appropriate. As the results suggest, this classification is less subjective, more precise, and more comprehensive than traditional ones based on selected isoglosses.
Shabbat and Shattered Dreams: Religious Accommodations for Public Exams in South Korea
Authors: Nam Soojin , Park Juhyun 
Published: April 2024

AbstractToday in South Korea, individuals of certain faiths are unable to take a wide range of state-administered qualifying examinations due to their religious convictions. The Constitutional Court of Korea has repeatedly refused their request for religious accommodations, such as an alternative test date for Sabbath or holy day observers who are unable to take exams on their original dates. The authors analyze the series of Constitutional Court decisions rejecting the need for such accommodation by focusing on the court’s use of its main analytical tool, the proportionality principle. These decisions reveal important shortcomings in the court’s application of the proportionality principle, including challenges inherent to proportionality and more specific deficiencies in the court’s application of the general principle. The article thus sheds light on how the proportionality principle is applied in the context of Korean constitutional jurisprudence and the resultant deprivation of protection for certain fundamental rights in Korea. The authors compare the court’s approach with that of courts in Spain, Switzerland, and the United States. They then propose a number of ways to improve the court’s proportionality analysis and its constitutional reasoning.
The Expressive Dimension of Free Exercise
Authors: Golemboski David 
Published: April 2024

AbstractExpressivist theories of law focus not only on what legal arrangements do but also what they communicate. The expressivist view has gained special currency in the context of religious establishment. Even when governmental involvement with religion is not coercive or does not materially violate anyone’s rights, it may nevertheless be undesirable by virtue of expressing a preference for a certain religion or a privileged status for certain religious groups over others. The existing literature, however, lacks an equivalent expressivist analysis of the related but distinct domain of free exercise of religion. What is expressed when a religious individual or group is granted special relief from the legal requirements that would otherwise apply to them? I argue that just like religious establishments, religious exemptions not only implicate rights and material interests but also have important expressive dimensions that both help account for their value and impose limits on their desirability.
Colombian Paramilitaries and Their Successor Groups
Authors: Wilson Suzanne B. 
Published: April 2024

This essay reviews the following works:The Frontier Effect: State Formation and Violence in Colombia. By Teo Ballvé. Ithaca, NY: Cornell University Press, 2020. Pp. 228. $27.95 paperback. ISBN: 9781501747540.Paramilitarismo. Balance de la contribución del CNMH al esclarecimiento histórico. By Centro Nacional de Memoria Histórica (CNMH). Bogotá: Centro Nacional de Memoria Histórica, 2018. Pp. 234. Free e-book. ISBN: 9789585500051.Agrarian Capitalism, War and Peace in Colombia: Beyond Dispossession. By Jacobo Grajales. New York: Routledge, 2021. Pp. 190. $44.95 paperback. ISBN: 978036775707.Clientelistic Warfare: Paramilitaries and the State in Colombia (1982-2007). By Francisco Gutiérrez Sanín. Oxford: Peter Lang, 2019. Pp. 480 pages. $72.95 hardcover. ISBN: 9781787073654.Borderland Battles: Violence, Crime, and Governance at the Edges of Colombia’s War. By Annette Idler. New York: Oxford University Press, 2019. Pp. 496. $29.00 paper. ISBN: 9780190849153.Organized Violence after Civil War: The Geography of Recruitment in Latin America. By Sarah Zukerman Daly. New York: Cambridge University Press, 2016. Pp. 344. $25.00 paperback. ISBN: 9781107566835.
Existential Inertia and Thomistic Esse
Authors: Boczar Jack 
Published: April 2024

AbstractIn recent years, a considerable amount of interest has arisen in the topic of existential inertia (henceforth EIT)
and its relation to the natural theology of Thomas Aquinas. While contemporary Thomists have engaged with proponents of EIT, strangely enough, no literature has focused on Aquinas’s own response to the objection(s) from an EIT-like position. The intention of this article is to (1) lay out the basic thrust of EIT and then (2) articulate how Aquinas’s own metaphysical commitments dissolve the problems that EIT raises. After formulating an argument based on Aqunias’s own texts and paying attention to the metaphysical commitments it involves, I then level three objections and respond to them.
A Miocene sperm whale (Cetacea, Physeteroidea) tooth from Liessel (Noord-Brabant, the Netherlands)
Authors: Snoodijk Felix , Wallaard Jonathan J. W. , Schulp Anne S. , Reumer Jelle W. F. 
Published: April 2024

Abstract
Here we report a well-preserved isolated physeteroid tooth of Late Miocene age from Liessel, the Netherlands. The presence of several morphological features allows attribution to the macroraptorial physeteroids. Size and morphology are to some extent comparable to Zygophyseter and almost identical to the primarily tooth-based Tortonian taxon Scaldicetus caretti. However, the genus Scaldicetus was declared unutilizable, which is supported here with an overview of modern classifications of Scaldicetus species and specimens. Despite the restrictions, the type species S. caretti is still valid, although the name is to be restricted to the type material. Based on its morphological resemblance, the tooth is identified as Physeteroidea indet. cf. Scaldicetus caretti.
Plastic pollution and human–primate interactions: A growing conservation concern
Authors: Anca Evelyn D. , Wallis Janette 
Published: April 2024

Abstract
As an anthropogenic creation, plastic pollution is a form of human–wildlife interaction and an emerging conservation threat to a growing number of species in both terrestrial and marine environments. Although plastic pollution has spread worldwide and a growing body of literature shows its effects on human health, little is known about its impact on our closest living relatives, nonhuman primates, and their habitats. With over 60% of primate species already under threat of extinction, plastic pollution in their habitats poses a unique problem, exposing them to physical harm, synthetic chemicals, and pathogens through ingestion, entanglement, and oral manipulation. Moreover, through its presence in soil, air, and waterways, plastic pollution leads to environmental degradation and reduces the quality and ecological functionality of primate habitats. This perspective article covers what is known so far about plastic pollution as a conservation threat to nonhuman primates. It is a call for primatologists to address plastic pollution in our research and conservation initiatives. By collecting data on plastic pollution’s presence and assessing its impact on primates and their habitats, we can develop safe protocols and prevention strategies to combat the threat of plastic pollution in the Anthropocene.
Estimation of Groundwater Residence Time Using Radiocarbon and Stable Isotope Ratio in Dissolved Inorganic Carbon and Soil CO2
Authors: Agrawal Rahul Kumar , Mohanty Ranjan Kumar , Rathi Ajayeta , Mehta Shreya , Yadava M G , Kumar Sanjeev , Laskar Amzad H 
Published: April 2024

AbstractEstimation of residence time of groundwater, particularly in regions with inadequate surface waters are very important for formulating sustainable groundwater management policies. We developed a technique for extracting dissolved inorganic carbon (DIC) quantitatively from water for measuring its 14C contents and presented the analytical details here. We also measured stable carbon isotope ratio (δ13C) in soil CO2 and groundwater DIC to correct the groundwater 14C ages. In addition, 14C in soil CO2 were measured for making necessary correction in the initial activity of the recharging water. The corrected 14C contents in the groundwater samples were used to estimate their residence times employing Lumped Parameter Models (LPM), a set of mathematical models to account for the processes that take place during transport from the recharge to the sampling spots. We present a case study focused on the calculation of radiocarbon ages and residence times for a groundwater sample collected from the campus of Physical Research Laboratory in Ahmedabad, Gujarat, India. The study also includes estimations of groundwater residence times using previously measured 14C ages of groundwater samples from Gujarat, India. Various factors controlling the groundwater ages in the LPM and their applicability are discussed.
A HOMEMADE SEMIAUTOMATIC GRAPHITIZATION DEVICE FOR AMS 14C DATING AT NTUAMS LAB
Authors: Shen Tzu-Tsen , Li Hong-Chun , Qiu Rick 
Published: April 2024

ABSTRACTA low-cost and computer-controlled graphitization system connected to an elemental analyzer (EA) has been designed and built at the NTUAMS Lab. This semiautomatic system equips 6-unit reactors for the graphitization of CO2 with H2 on the iron catalyst. The entire procedure takes about 7 hours for iron conditioning, sample combustion and loading, and graphitization. The system can produce good-quality graphite for samples containing 0.5–1.6 mg carbon mass, with the pressure yield of graphitization ranging from 57.7% to 87.1%. The average values of OXI and OXII agree well with the consensus value, but the result of ANU sucrose was observed to be slightly higher than the reported one. The background samples of anthracite over ten months yielded an average of 0.38±0.10 pMC (n=21) corresponding to a 14C age of 45 kyr BP. Intercomparison samples L and M of FIRI exhibit that the measured 14C ages are almost identical to the consensus values and have a small spread in these values. The system has been carrying out graphitization for total organic carbon (TOC) of peat samples, and providing a more efficient and convenient way for AMS 14C dating.
A systematic review of the effect of dietary and nutritional interventions on the behaviours and mental health of prisoners
Authors: Poulter Matthew , Coe Shelly , Graham Catherine Anna-Marie , Leach Bethan , Tammam Jonathan 
Published: April 2024

AbstractPrisoners experience a higher burden of poor health, aggressive behaviours and worsening mental health than the general population. This systematic review aimed to identify research that used nutrition-based interventions in prisons, focusing on outcomes of mental health and behaviours. The systematic review was registered with Prospective Register of Systematic Reviews on 26 January 2022: CRD42022293370. Inclusion criteria comprised of current prisoners with no limit on time, location, age, sex or ethnicity. Only quantitative research in the English language was included. PubMed/Medline, Web of Science, EMBASE, PsycINFO and CINAHL were searched, retrieving 933 results, with 11 included for qualitative synthesis. Studies were checked for quality using the revised tool to assess risk of bias in randomised trials or risk of bias in non-randomised studies of interventions tool. Of the included studies, seven used nutritional supplements, three included diet changes, and one used education. Of the seven supplement-based studies, six included rule violations as an outcome, and only three demonstrated significant improvements. One study included mental health as an outcome; however, results did not reach significance. Of the three diet change studies, two investigated cognitive function as an outcome, with both reaching significance. Anxiety was included in one diet change study, which found a significant improvement through consuming oily fish. One study using diet education did not find a significant improvement in overall mental resilience. Overall, results are mixed, with the included studies presenting several limitations and heterogeneity. Future research should aim to consider increased homogeneity in research design, allowing for a higher quality of evidence to assess the role nutrition can play in improving the health of prisoners.
Weak amenability for dual Banach algebras
Authors: Mahmoodi Amin 
Published: April 2024

AbstractA suitable notion of weak amenability for dual Banach algebras, which we call weak Connes amenability, is defined and studied. Among other things, it is proved that the measure algebra M(G) of a locally compact group G is always weakly Connes amenable. It can be a complement to Johnson’s theorem that $L^1(G)$ is always weakly amenable [10].
Late Silurian event stratigraphy and facies of South Wales and the Welsh Borderland, United Kingdom
Authors: Hillier Robert D , Waters Richard A , Davies Jeremy R , Higgs Kenneth T , Molyneux Stewart G 
Published: April 2024

AbstractLithofacies and biostratigraphical analysis has enabled the establishment of a stratigraphic event framework for Ludfordian and Pridoli strata in south Wales and the Welsh Borderland. In SW Wales, the Golden Grove Axis acted as a structural hinge separating the shallow marine storm-influenced Cae’r mynach Seaway from a pediment surface above which Ludfordian colluvium (Abercyfor Formation) was deposited. The Axis seeded four NW-derived river-influenced delta progrades of Leintwardinian to early Pridoli age (Tilestones Formation). A NE-sourced early Pridoli wave-influenced delta deposited the Downton Castle Sandstone Formation (DCSF), coeval to the youngest Tilestones prograde, with a lateral interface existing between Mynydd Epynt and the Clun Forest area. Except for the Malverns area, the DCSF is no longer recognized south of the Neath Disturbance. Early Pridoli forced regression promoted widespread subaerial exposure north of the Neath Disturbance, with incision into tracts close to the Welsh Borderland Fault System. The basinward-shift in facies belts resulted in marine erosion and deposition of a phosphatic ravinement pebble lag. The wave-influenced Clifford’s Mesne Sandstone Formation delta subsequently seeded on the Gorsley Axis with tidally influenced Rushall Formation accumulating in a back-barrier setting. The Pwll-Mawr Formation records the easterly advance of coeval coastal deposits on the western side of the remnant Cae’r mynach Seaway. Behind migrating delta coastlines, green muds accumulated on coastal plains (Temeside Mudstone Formation) with better drained red dryland alluvium (Moor Cliffs Formation) charting expansion of Old Red Sandstone lithofacies. Mid-Pridoli incision preserves the Pont ar Llechau Formation estuarine valley fill.
Custom Versus Customary Law: Does South African Jurisprudence Draw the Distinction?
Authors: Osman Fatima 
Published: April 2024

AbstractThis article presents a critical analysis of whether South African courts employ established theoretical concepts to delineate the boundaries between custom and customary law. To facilitate a comprehensive understanding, the article begins by providing an overview of the South African legal system, laying the groundwork for the subsequent discussion. The article then delves into prominent theories that address the differentiation between custom and customary law, providing a succinct summary of each. Finally, the article examines the degree to which these theories have been embraced by the courts. Notably, the article uncovers the courts’ emphasis on factors such as certainty and the protection of human rights when deciding whether to apply customary law, rather than relying solely on the distinction between custom and customary law.
Evaluation of epiphytic microbiota in red clover and alfalfa on silage fermentation products, bacterial community diversity and functionality of oat
Authors: Wang Siran , Li Junfeng , Zhao Jie , Dong Zhihao , Nazar Mudasir , Kaka Niaz Ali , Lin Ziqun , Shao Tao 
Published: April 2024

AbstractThe purpose of this experiment was to evaluate the contribution of epiphytic microbiota on alfalfa (AL), oat (OT), and red clover (RC) to ensiling characteristics and bacterial community diversity of oat. With the irradiation of γ-ray, sterile OT (~233 g/kg dry matter (DM)) was inoculated by sterile water (STOT), epiphytic microbiota from OT (OTOT), AL (OTAL) and RC (OTRC), respectively. Triplicate silage-bags for each treatment were sampled after different days (1, 3, 7, 15, 30 and 60) of fermentation, respectively. Similar chemical compositions were found between fresh oat and STOT. Lower (P < 0.05) contents of ammonia nitrogen (NH3-N) and higher (P < 0.05) accumulation of lactic acid were found in OTAL compared with OTRC and OTOT on day 3. The greatest (P < 0.05) NH3-N, acetic acid concentrations and pH and the lowest (P < 0.05) concentration of lactic acid were found in OTRC on day 60. After 3 days of ensiling, Lactobacillus accounted for a big proportion in OTAL and OTOT, and Hafnia-Obesumbacterium was predominant in OTRC. The bacterial communities in OTAL and OTOT had lower (P < 0.05) abundances of ‘Genetic Information Processing’ than OTRC after 3 days. Overall, the composition, diversity, and activity of epiphytic microbiota can notably influence the ensiling characteristics of forage oat. The lactic acid bacteria (hetero-fermentative type) and Enterobacteriaceae species played an important role in producing ethanol contents during the ensiling of forage oat.
The role of using the submucosal conchoplasty technique for the management of concha bullosa in decreasing post-operative middle meatus synechia formation after functional endoscopic sinus surgery: a randomised controlled trial
Authors: Elgendy Ahmed , Khafagy Yasser , Elzayat Saad , Ali Elouny Ali Gamal 
Published: April 2024

AbstractObjectiveThe study aimed to compare the applicability of classic lateral lamellectomy versus submucosal conchoplasty techniques in managing concha bullosa during and after functional endoscopic sinus surgery.MethodsThe study randomly divided 56 patients with bilateral concha bullosa into two groups. One group of patients underwent the submucosal conchoplasty technique and the other group underwent the lateral lamellectomy technique. The study compared the intra-operative findings, including the time required for each technique, the amount of intra-operative bleeding and the post-operative endoscopic outcome of the middle meatus and middle turbinate stability.ResultsSubmucosal conchoplasty was significantly more time-consuming than the lateral lamellectomy technique (p = 0.001*). The difference in the intra-operative amount of bleeding was (p = 0.086*). The lateral lamellectomy group showed a higher rate of synechia formation in the middle meatus (p = 0.012*).ConclusionSubmucosal conchoplasty is a valid technique for managing concha bullosa with better post-operative endoscopic outcomes.