bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and Disparities in Telehealth Use Among US Adults Following the COVID-19 Pandemic: National Cross-Sectional Survey
Authors: Spaulding Erin M , Fang Michael , Commodore-Mensah Yvonne , Himmelfarb Cheryl R , Martin Seth S , Coresh Josef 
Published: May 2024

Background
Telemedicine expanded during the COVID-19 pandemic, though use differed by age, sex, race or ethnicity, educational attainment, income, and location. It is unclear if high telehealth use or inequities persisted late into the pandemic.

Objective
This study aims to evaluate the prevalence of, inequities in, and primary reasons for telehealth visits a year after telemedicine expansion.

Methods
We used cross-sectional data from the 2022 Health Information National Trends Survey (HINTS 6), the first cycle with data on telemedicine. In total, 4830 English- and Spanish-speaking US adults (aged ≥18 years) were included in this study. The primary outcomes were telehealth visit attendance in the 12 months before March 7, 2022, to November 8, 2022, and the primary reason for the most recent telehealth visit. We evaluated sociodemographic and clinical predictors of telehealth visit attendance and the primary reason for the most recent telehealth visit through Poisson regression. Analyses were weighted according to HINTS 6 standards.

Results
We included 4830 participants (mean age 48.3, SD 17.5 years; 50.28% women; 65.21% White). Among US adults, 38.78% reported having a telehealth visit in the previous year. Telehealth visit attendance rates were similar across age, race or ethnicity, income, and urban versus rural location. However, individuals with a telehealth visit were less likely to live in the Midwest (adjusted prevalence ratio [aPR] 0.65, 95% CI 0.54-0.77), and more likely to be women (aPR 1.21, 95% CI 1.06-1.38), college graduates or postgraduates (aPR 1.24, 95% CI 1.05-1.46), covered by health insurance (aPR 1.56, 95% CI 1.08-2.26), and married or cohabitating (aPR 1.17, 95% CI 1.03-1.32), adjusting for sociodemographic characteristics, frequency of health care visits, and comorbidities. Among participants with a telehealth visit in the past year, the primary reasons for their most recent visit were minor or acute illness (32.15%), chronic disease management (21%), mental health or substance abuse (16.94%), and an annual exam (16.22%). Older adults were more likely to report that the primary reason for their most recent telehealth visit was for chronic disease management (aPR 2.08, 95% CI 1.33-3.23), but less likely to report that it was for a mental health or substance abuse issue (aPR 0.19, 95% CI 0.10-0.35), adjusting for sociodemographic characteristics and frequency of health care visits.

Conclusions
Among US adults, telehealth visit attendance was high more than a year after telemedicine expansion and did not differ by age, race or ethnicity, income, or urban versus rural location. Telehealth could continue to be leveraged following COVID-19 to improve access to care and health equity.
Spanish and Catalan Versions of the eHealth Literacy Questionnaire: Translation, Cross-Cultural Adaptation, and Validation Study (Preprint)
Authors: Hernández Encuentra Eulàlia , Robles Noemí , Angulo-Brunet Ariadna , Cullen David , del Arco Ignacio 
Published: May 2024

BACKGROUND

The rise of digital health services, especially following the outbreak of COVID-19, has led to a need for health literacy policies that respond to people’s needs. Spain is a country with a highly developed digital health infrastructure, but there are currently no tools available to measure digital health literacy fully. A well-thought-through questionnaire with strong psychometric properties such as the eHealth Literacy Questionnaire (eHLQ) is important to assess people’s eHealth literacy levels, especially in the context of a fast-growing field such as digital health.

OBJECTIVE

This study aims to adapt the eHLQ and gather evidence of its psychometric quality in 2 of Spain’s official languages: Spanish and Catalan.

METHODS

A systematic cultural adaptation process was followed. Data from Spanish-speaking (n=400) and Catalan-speaking (n=400) people were collected. Confirmatory factor analysis was used to confirm the previously established factor structure. For reliability, the Cronbach α and categorical ω were obtained for every subscale. Evidence of convergent and discriminant validity was provided through the correlation with the total score of the eHealth Literacy Scale. Evidence based on relations to other variables was evaluated by examining extreme values for educational level, socioeconomic level, and use of technology variables.

RESULTS

Regarding the confirmatory factor analysis, the 7-factor correlated model and the 7 one-factor models had adequate goodness-of-fit indexes for both Spanish and Catalan. Moreover, measurement invariance was established between the Spanish and Catalan versions. Reliability estimates were considered adequate as all the scales in both versions had values of &gt;0.80. For convergent and discriminant validity evidence, the eHealth Literacy Scale showed moderate correlation with eHLQ scales in both versions (Spanish: range 0.57-0.76 and <i>P</i>&lt;.001; Catalan: range 0.41-0.64 and <i>P</i>&lt;.001). According to the relationship with external variables, all the eHLQ scales in both languages could discriminate between the maximum and minimum categories in level of education, socioeconomic level, and level of technology use.

CONCLUSIONS

The Spanish and Catalan versions of the eHLQ appear to be psychometrically sound questionnaires for assessing digital health literacy. They could both be useful tools in Spain and Catalonia for researchers, policy makers, and health service managers to explore people’s needs, skills, and competencies and provide interesting insights into their interactions and engagement regarding their own experiences with digital health services, especially in the context of digital health growth in Spain.

CLINICALTRIAL
BIOSYNTHESIS, CHARACTERIZATION AND EVALUATION OF SILVER NANOPARTICLES FROM THE LEAF EXTRACT OF PREMNA INTIGRIFOLIA L. AS A POTENTIAL ANTICANCER AGENT
Authors: K. SPANDANA , SHETTAR ARUN K. , S. RASHMI 
Published: May 2024

Objective: In this study, plant-based silver nanoparticles were synthesized and characterized from Premna integrifolia leaf extract to test the viability towards anticancer properties.
Methods: Preliminary identification of silver nanoparticles was validated by Visual observation and confirmed for the characterization by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDX) and Fourier-transform Infrared Spectroscopy (FTIR) analysis. Further synthesized nanoparticles were evaluated against non-small lung cancer cells (A549) by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay.
Results: Aqueous leaf extract of Premna intigrifolia was synthesized for silver nanoparticles and showed an average size from 35nm to 100 nm through SEM studies. EDX showed a strong signal confirming the formation of silver nanoparticles in the metallic silver region at 5Kev, and the FTIR spectrum showed changes in some peaks of the aqueous extract with functional groups. The newly synthesized silver nanoparticles showed significant anticancer properties targeting lung cancer A549 cell line against standard drug Epotoside with a 50% Inhibitory Concentration (IC50) value of 78.431 µg.
Conclusion: The results affirm that biosynthesized silver nanoparticles can be used as an alternative to chemical medicines to cure cancer.
Polygenic Risk Score Modifies the Association of HbA1c With Hearing Loss in Middle-Aged and Older Chinese Individuals: The Dongfeng-Tongji Cohort
Authors: He Yaling , Wang Zhichao , Zhang Haiqing , Lai Xuefeng , Liu Miao , Yang Liangle , Zheng Yiquan , He Meian , Kong Weijia , Zhang Xiaomin 
Published: May 2024

OBJECTIVE
Evidence regarding the modifying effect of the polygenic risk score (PRS) on the associations between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these associations can be influenced by genetic susceptibility.

RESEARCH DESIGN AND METHODS
This cross-sectional study included 13,275 participants aged 64.9 years from the Dongfeng-Tongji cohort. HL was defined according to a pure tone average &gt;25 dB in the better ear and further classified by severity. Prediabetes and type 2 diabetes (T2D) were defined based on the 2013 criteria from the American Diabetes Association. A PRS was derived from 37 single nucleotide polymorphisms associated with HL. Multivariable logistic regression models were fitted to estimate the associations of PRS and glycemic traits with HL and its severity.

RESULTS
Elevated fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), and T2D were positively associated with higher HL risks and its severity, with odds ratios (ORs) ranging from 1.04 (95% CI 1.00, 1.08) to 1.25 (95% CI 1.06, 1.46). We also found significant interaction between HbA1c and PRS on risks of overall HL and its severity (P for multiplicative interaction &lt;0.05), and the effects of HbA1c on HL risks were significant only in the group with high PRS. Additionally, compared with normoglycemia in the group with low PRS, T2D was associated with an OR of up to 2.00 and 2.40 for overall HL and moderate to severe HL, respectively, in the group with high PRS (P for additive interaction &lt;0.05).

CONCLUSIONS
PRS modifies the association of HbA1c with HL prevalence among middle-aged and older Chinese individuals.
Remanufacturing closed-loop supply chain decision comparison under multiple carbon policies
Authors: Feng Yangang , Li Xuemeng 
Published: May 2024

Abstract
This article constructs a closed-loop supply chain system including a single manufacturer and a single retailer and studies the optimal decision problem of enterprises under three different carbon reduction policies. Three supply chain game models were constructed to research the impact of different carbon reduction policies on the decisions of supply chain members. The results revealed that:(1) The carbon emission reduction level of the manufacturer is negatively correlated with the recycling price of used products and the abatement cost factor;(2) When the carbon trading price is equal to the tax rate, the carbon cap and trade policy is more conducive to promoting the manufacturer to improve the level of carbon emission reduction;(3) When the carbon trading price is low, mixed carbon policy is more favorable for the manufacturer to increase its carbon emission reduction. The research results of this study can provide certain suggestions for the government to implement a reasonable carbon reduction policy.
A study on the influencing factors and improvement strategies of perceived value of recreational fishing customers on their willingness to revisit
Authors: Ran Zhou , Qijun Jiang 
Published: May 2024

Abstract
As the main service target of recreational fishery operators, customers’ willingness to revisit has a profound impact on stimulating the rapid development of recreational fishery. However, there is currently little research on the influencing factors and improvement strategies of recreational fishery customers’ willingness to revisit from the perspective of perceived value. This article selects 500 customers participating in recreational fishing in Chun’an County and Xiangshan County, Zhejiang Province, China as the research objects, and uses the fuzzy set qualitative comparative analysis method to explore the influencing factors of recreational fishing customers’ willingness to revisit. Research has found that: (1) Economic value and experiential value play a core role in four conditional configurations that lead to high customer revisit intention, and are key factors affecting the high revisit intention of recreational fishing customers; (2) two conditional configurations lead to low revisit intention of recreational fishery customers, and the lack of economic value plays a core role in these two conditional configurations, which are the key factors affecting the low revisit intention of recreational fishery customers; (3) Based on the controllability of conditional factors, it can be concluded that providing economically applicable and experiential recreational fishery services is the best strategy to enhance customers’ willingness to revisit. This study, under the synergistic effect of multiple conditions, reveals the complexity of factors influencing customer revisit intention. Setting reasonable charging standards and improving customer experience are inevitable choices to enhance the revisit intention of recreational fishing customers.
Effect of Light on Dairy Cattle in Farm Conditions – A Review
Authors: Adamczyk Krzysztof , Herbut Piotr , Godyń Dorota , Angrecka Sabina , Kupczyński Robert , Vieira Frederico Márcio Corrêa 
Published: May 2024

Abstract
Cattle are among the animals with diurnal activity, which is due to the specific animal–environment relationship and the natural role wild cattle play in the ecosystem. As humans began domesticating, breeding these animals, they became an integral part of this relationship. This review article addresses the most important current issues: 1) a characterisation of contemporary knowledge on the biological determinants of the vision abilities of dairy cattle, 2) a discussion of the relationship between these abilities and animal health and performance, and 3) a characterisation of the light–animal relationship under husbandry conditions. The intricate link between the anatomical and physiological aspects of visual function in cattle and their circadian rhythms was emphasised. This connection directly influences cattle growth and development, as well as the health and performance of dairy cows during the long/short day photoperiods. The article also considers the possibility of managing dairy cows’ photoperiod and light quality to enhance their performance and overall well-being.
A New Strain of Saccharomyces cerevisiae in Diets of Lactating Holstein Cows Improved Feed Efficiency and Lactation Performance
Authors: Azzaz Hossam H. , Kholif Ahmed E. , Murad Hussein A. , Hassaan Noha A. , Vargas-Bello-Pérez Einar 
Published: May 2024

Abstract
This study compared the effects of feeding a new strain of Saccharomyces cerevisiae HSA2020 with a commercial strain on in vitro rumen fermentation and production performance of dairy cows. Permeate was used as a substrate for the laboratory production of the new strain of S. cerevisiae after the hydrolysis by β-galactosidase (5000 µ/mL at 37°C). Two experiments were conducted: in Experiment 1, the effects of three levels (1, 2 and 3 g/kg dry matter) of S. cerevisiae on in vitro ruminal fermentation kinetics were evaluated. In Experiment 2, for 60 days, sixty multiparous Holstein cows (639±24.8 kg BW, 3±1 parity, 7±1 days in milk, with a previous milk production of 23±2.0 kg/d) during the previous lactation, were randomly assigned to 3 treatments in a completely randomized design. Cows were fed without any additives (control treatment) or supplemented with 2 g/kg feed daily of laboratory produced (PY) or commercial (CY) S. cerevisiae. In Experiment 1, inclusion of PY and CY increased (P<0.05) gas production, propionate, and nutrient disappearance, while decreased (P<0.05) methane production and protozoal count. Moreover, in Experiment 2, PY followed by CY increased (P<0.01) nutrient digestibility, and serum concentrations of total protein, albumin, and glucose (P<0.05). Higher daily milk yield, and milk energy output were observed with PY and CY without affecting concentrations of milk components or milk fatty acid profile. Compared to control, increased feed efficiency was observed with PY and CY. Compared to PY, CY increased serum concentrations of urea-N and decreased triglycerides, while PY decreased serum aspartate transaminase and increased concentration of conjugated linoleic acids in milk. In early lactating cow diets, both strains of S. cerevisiae improved production performance at 2 g/kg, and minimal differences between strains were found.
Animal Models for the Treatment of Human Diseases – A Review
Authors: Jura Jacek 
Published: May 2024

Abstract
Currently, studies conducted on animal models provide new insight into the aetiology and course of various pathological conditions in humans. Due to the cause of disease, animal models can be divided into two categories: natural models, such as nude mice, and induced models, such as transgenic pigs. This article discusses several examples of animal models and their contributions to the development of effective therapies for human diseases such as muscular dystrophy, cystic fibrosis, and atherosclerosis. In addition, we presented the latest news on gene therapy, xenotransplantation, and drug trials in humans and animals.
Biological Removal of Nitrogenous Waste Compounds in the Biofloc Aquaculture System – A Review
Authors: Khanjani Mohammad Hossein , Zahedi Saeed , Sharifinia Moslem , Hajirezaee Saeed , Singh Soibam Khogen 
Published: May 2024

Abstract
Aquaculture has experienced significant global expansion and is considered one of the fastest-growing sectors in food production. However, there exist additional challenges that restrict the capacity to achieve maximum efficiency in aquaculture systems, such as issues over water quality and shortages of appropriate live feeds. Intensive aquaculture systems involve the use of protein-rich prepared feed for feeding the cultured animals. This may give rise to the discharge of nitrogenous compounds into the water, which can pose a risk to the environment when present in excessive quantities beyond the acceptable levels. In recent years, an innovative method called biofloc technology (BFT) has become a practical solution to this issue. Undoubtedly, BFT offers a groundbreaking method for nutrient disposal that eradicates the requirement for excessive water use or equipment maintenance. Three primary types of microorganisms are crucial in alleviating the adverse impacts of nitrogen compounds in this technique. Photoautotrophs participate in the processes of removal and absorption, whereas chemoautotrophs promote nitrification and conversion. Heterotrophs contribute to the absorption process. Biofloc predominantly consists of heterotrophic bacteria, alongside algae, protozoa, rotifers, and nematodes. While there have been reviews carried out on multiple aspects of biofloc technology, there exists a lack of literature that tackles this particular field of research progress. This article discusses every aspect and techniques of biological management used for removing nitrogenous waste compounds in biofloc aquaculture systems.
Exploring the use of metabarcoding to reveal eukaryotic associations with mononchids nematodes
Authors: Maosa Joseph O. , Wang Siqi , Liu Shuhan , Li Hongmei , Qing Xue , Bert Wim 
Published: May 2024

Abstract
Nematodes play a vital ecological role in soil and marine ecosystems, but there is limited information about their dietary diversity and feeding habits. Due to methodological challenges, the available information is based on inference rather than confirmed observations. The lack of correct dietary requirements also hampers rearing experiments. To achieve insight into the prey of mononchid nematodes, this study employed high-throughput Illumina paired-end sequencing using universal eukaryotic species 18S primers on 10 pooled mononchid nematode species, namely Mylonchulus brachyuris, M. brevicaudatus, Mylonchulus sp., Clarkus parvus, Prionchulus sp. M. hawaiiensis, M. sigmaturellus, M. vulvapapillatus, Anatonchus sp. and Miconchus sp. The results indicate that mononchids are associated with a remarkable diversity of eukaryotes, including fungi, algae, and protists. While the metabarcoding approach, first introduced here for mononchids, proved to be a simple and rapid method, it has several limitations and crucial methodological challenges that should be addressed in future studies. Ultimately, such methods should be able to evaluate the dietary complexity of nematodes and provide a valuable avenue for unraveling the dietary requirements of previously unculturable nematodes. This can contribute to the methodology of understanding their feeding habits and contributions to ecosystem dynamics.
Burnout Phenomenon on Principals: Impact on Behavior and its Mitigation Strategies
Authors: Andika Carter Bing , Sihombing Sabrina Oktoria , Tan Jacob Donald , Berlianto Margaretha Pink 
Published: May 2024

Objective: This research was conducted to gain further understanding of the real experiences (life experiences) of private school principals in order to reveal the substantive meaning of the entire process of their experience of the burnout phenomenon through personal interactions with the principals who were the research subjects which were then articulated through a burnout model that explains more about the processes and factors that play a role in the dynamics of the burnout phenomenon that apply specifically to the subject of school principals.

Theoretical Framework: Qualitative research conducted using the phenomenological approach. Research validity was obtained through triangulation of data sources and cross perspectives. Research reliability was obtained through data saturation and in-depth-understanding of the subject from the selected informants.

Method: 12 school principals that have worked for around 5-17 years are selected through criteria matching for interviews. This research uses narrative analysis of stories obtained from in-depth interviews with research informants.

Result and conclusion: This research has presented evidence that although the role of a leader is very important to motivate and improve the performance of the people being led, in fact the same thing also applies vice versa, the more the people being led or managed can be cooperative with the leader, the more positive the performance of a leader, especially for private school principals in Indonesia. On the other hand, educational foundations as the authority to supervise school principals also have a role in creating a conducive situation for school principals to carry out their duties as well as possible.

Research Implications: This research point out several potential steps that need to be taken by educational foundations or organizations that manage an educational institution. This is to ensure that anyone who serves as a school principal can play their role appropriately, efficiently, and produce added value to the organization in the long term.

Originality/Value: The findings of this research reinforce theories regarding the burnout phenomenon that have existed so far, by enriching and clarifying the understanding of the meaning of the phenomenon by which the burnout phenomenon occurs at the leadership level in education industry nowadays.