bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neurosurgical treatment of spasticity: a potential return to the cerebellum
Authors: Cummins Daniel D. , Park Hyun Joo , Panov Fedor 
Published: June 2024

OBJECTIVE
Neurosurgical targeting of the cerebellar dentate nucleus via ablative dentatotomy and stimulation of the dentate nucleus was historically used for effective treatment of spasticity. Yet for decades, neurosurgical treatment of spasticity targeting the cerebellum was bypassed in favor of alternative treatments such as intrathecal baclofen pumps and selective dorsal rhizotomies. Cerebellar neuromodulation has recently reemerged as a promising and effective therapy for spasticity and related movement disorders.

METHODS
In this narrative review, the authors contextualize the historical literature of cerebellar neuromodulation, comparing it with modern approaches and exploring future directions with regard to cerebellar neuromodulation for spasticity.

RESULTS
Neurosurgical intervention on the cerebellum dates to the use of dentatotomy in the 1960s, which had progressed to electrical stimulation of the cerebellar cortex and dentate nucleus by the 1980s. By 2024, modern neurosurgical approaches such as tractography-based targeting of the dentate nucleus and transcranial magnetic stimulation of cerebellar cortex have demonstrated promise for treating spasticity.

CONCLUSIONS
Cerebellar neuromodulation of the dentate nucleus and cerebellar cortex are promising therapies for severe cases of spasticity. Open areas for exploration in the field include the following: tractography-based targeting, adaptive cerebellar stimulation, and investigations into the network dynamics between the cerebellar cortex, deep cerebellar nuclei, and the subcortical and cortical structures of the cerebrum.
Actigraph-based quantification of sleep in children with dystonia undergoing deep brain stimulation
Authors: Zhang Frederick , Mithani Karim , Breitbart Sara , Yan Han , Fasano Alfonso , Ibrahim George M. , Gorodetsky Carolina 
Published: June 2024

OBJECTIVE
Dystonia is among the most common pediatric movement disorders and can manifest with a range of debilitating symptoms, including sleep disruptions. The duration and quality of sleep are strongly associated with quality of life in these individuals and could serve as biomarkers of dystonia severity and the efficacy of interventions such as deep brain stimulation (DBS). Thus, this study investigated sleep duration and its relationship to disease severity and DBS response in pediatric dystonia.

METHODS
Actigraphs (wearable three-axis accelerometers) were used to record multiday sleep data in 22 children with dystonia, including 6 patients before and after DBS implantation, and age- and sex- matched healthy controls. Data were preprocessed, and metrics of sleep duration and quality were extracted. Repeated-measures statistical analyses were used.

RESULTS
Children with dystonia slept less than typically developing children (p = 0.009), and shorter sleep duration showed trending correlation with worse dystonia severity (r = −0.421, p = 0.073). Of 4 patients who underwent DBS and had good-quality data, 1 demonstrated significantly improved sleep (p < 0.001) postoperatively. Reduction in dystonia severity strongly correlated with increased sleep duration after DBS implantation (r = −0.965, p = 0.035).

CONCLUSIONS
Sleep disturbances are an underrecognized marker of pediatric dystonia severity, as well as the effectiveness of interventions such as DBS. They can serve as objective biomarkers of disease burden and symptom progression after treatment.
Evaluation of the long-term effect of selective tibial neurotomy for the treatment of spastic foot using a personal goal-centered approach
Authors: Dauleac Corentin , Luaute Jacques , Rode Gilles , Sindou Marc , Mertens Patrick 
Published: June 2024

OBJECTIVE
The objective of this study was to evaluate the long-term effectiveness of selective tibial neurotomy (STN) for the treatment of the spastic foot using a goal-centered approach.

METHODS
Between 2011 and 2018, adult patients with a spastic foot (regardless of etiology) who received STN followed by a rehabilitation program were included. The primary outcome was the achievement of individual goals defined preoperatively (T0) and compared at 1-year (T1) and 5-year (T5) follow-up by using the Goal Attainment Scaling methodology (T-score). The secondary outcomes were the presence of spastic deformities (equinus, varus, and claw toes), modified Ashworth scale (MAS) score for the targeted muscles, and modified Rankin Scale (mRS) score at T0, T1, and T5.

RESULTS
Eighty-eight patients were included. At T5, 88.7% of patients had achieved their goals at least "as expected." The mean T-score was significantly higher at T1 (62.5 ± 9.5) and T5 (60.6 ± 11.3) than at T0 (37.9 ± 2.8) (p < 0.0001), and the difference between T1 and T5 was not significant (p = 0.2). Compared to T0, deformities (equinus, varus, and claw toes; all p < 0.0001), MAS score (p < 0.0001), and mRS score (p < 0.0001) were significantly improved at T1 and T5. Compared to T1, MAS score increased slightly only at T5 (p = 0.05) but remained largely below the preoperative value. There was no difference between T1 and T5 regarding other clinical parameters (e.g., deformities, walking abilities, mRS score).

CONCLUSIONS
This study found that STN associated with a postoperative rehabilitation program can enable patients to successfully achieve personal goals that are sustained within a 5-year follow-up period.
Spinal catheter revision in pediatric intrathecal baclofen pumps: risk factors and postoperative outcomes
Authors: Mosher Amanda M. , Hartman Emma , Keusch Dylan , Papadakis Joanna E. , Buxton Kristin , Morgan Ann , Stone Scellig S. D. , Northam Weston T. 
Published: June 2024

OBJECTIVE
Intrathecal baclofen (ITB) pumps are commonly used in pediatric patients with cerebral palsy (CP) and medically refractory spasticity. However, catheter malfunction and associated risk factors are not well understood. The aim of this study was to examine potential risk factors for spinal catheter malfunction and characterize postoperative follow-up to understand the clinical consequences.

METHODS
Patients who received ITB pump replacement or revision at Boston Children’s Hospital between 2010 and 2023 were retrospectively reviewed. The spinal catheter revision cohort (SCRC) included patients whose spinal catheter was occluded requiring lumbar catheter revision. The second cohort included abdominal pump replacements only (APRC). Between-group comparisons and multivariable regression identified factors associated with catheter revision and postoperative outcomes.

RESULTS
Forty-one (33.6%) patients underwent spinal catheter revision and were compared with 81 patients (66.4%) who underwent abdominal pump replacement only. Younger age at surgery and an elevated preoperative lower-extremity modified Ashworth scale grade were associated with spinal catheter revision (p < 0.05). Catheter model type, tip location, and history of spinal fusion were not associated with obstruction. Postoperatively, SCRC patients experienced a higher rate of infection (17.1%) relative to APRC patients (0%) within 30 days from their ITB pump replacement procedure (p < 0.05) and greater likelihood of subsequent ITB system removal compared with the APRC (24.4% vs 7.4%, p < 0.05). Although not differing preoperatively, SCRC patients had lower postoperative ITB doses when compared with the APRC group (median dose 143 vs 350 µg/day, p < 0.05) at hospital discharge and remained statistically different at the 6-month and 1-year follow-ups (p < 0.05). There were no postoperative differences in baclofen overdose, withdrawal, or median number of hospital readmissions within 30 days. Overall, 31.7% of spinal catheter revisions were unanticipated by the clinical team at time of surgery.

CONCLUSIONS
Younger age at surgery and increased preoperative lower-extremity tone may be risk factors for catheter obstruction, resulting in a higher rate of postoperative infection and subsequent ITB pump removal compared with pump replacement alone. Spinal catheter occlusion can complicate revision or replacement procedures, especially when unanticipated. Routine clinical assessment may be inadequate for diagnosing insidious catheter malfunction. Catheter occlusion deserves further study, and routine assessment of catheter patency may be warranted to prevent suboptimal tone therapy.
Ventriculoperitoneal shunt placement following endoscopic third ventriculostomy failure in the treatment of pediatric hydrocephalus
Authors: Evans Alexander R. , Villeneuve Lance , Bowen Ira , Carter Lacey , Chen Sixia , Kimmell Marianne , Gernsback Joanna , Balsara Karl , Jea Andrew , Desai Virendra R. 
Published: June 2024

OBJECTIVE
The goal of this study was to evaluate the impact of endoscopic third ventriculostomy (ETV) failure on subsequent risk of ventriculoperitoneal shunt (VPS) placement.

METHODS
A retrospective chart review was performed to identify pediatric patients receiving ETV followed by a VPS at Oklahoma Children’s Hospital between January 1, 2016, and December 31, 2021. A control group of patients receiving a VPS alone was also gathered. Complication and shunt failure rates were compared between the 2 groups at 12 months postoperatively.

RESULTS
A total of 222 patients were included in this study. The VPS placement after ETV failure (VPSEF) group included 21 patients; 53% were male and 47% were female, with a mean age of 2.2 years and standard deviation of 4.3 years. The etiology of hydrocephalus was chiefly intraventricular hemorrhage (43%) and neural tube defects (19%). At 12 months after VPS placement, the complication rate was 24%, predominantly including infection (19%) or CSF leakage (10%).
The VPS-only (VPSO) group included 201 patients; 51% were male and 49% were female, with a mean age of 4.2 years and standard deviation of 6.5 years. The etiology of hydrocephalus was chiefly intraventricular hemorrhage (26%) and neural tube defects (30%). At 12 months postoperatively, the complication rate was 10%, predominantly including infection (6%) or catheter-associated hemorrhage (3%). The difference in complication rates between the VPSEF and VPSO groups was not significant at 12 months postoperatively (p = 0.07); however, on subgroup analysis there was a significantly higher rate of CSF leakage at 12 months in the VPSEF group compared to the VPSO group (p = 0.0371).

CONCLUSIONS
There was no difference in overall complication rates for the treatment of pediatric hydrocephalus by VPS following failed ETV compared to VPS placement alone, yet prior ETV may predispose patients to a higher rate of CSF leaks within 12 months of VPS placement. Further study is indicated to determine whether a prior ETV procedure predisposes patients to a higher complication rate on VPS placement.
FUNGSI PENGAWASAN DEWAN PERWAKILAN RAKYAT DAERAH TERHADAP PEMERINTAH DAERAH BERDASARKAN UNDANG-UNDANG DASAR 1945
Authors: Zulfia Sophi 
Published: June 2024

Function Local House of Representatives to local governments based on the 1945 Constitution, the main problem of this research is to find out how the implementation of the regulation of the DPRD's supervisory function on local governments in the Unitary State of the Republic of Indonesia which is based on decentralization, with identification studies. what indicators are used to optimize the local House of Representaitives oversight function of local governments and what is the proper concept of supervision that can be carried out by the Local House of Representatives on local governments.
FATWA IN THE DIGITAL ERA: COMMUNICATION STRATEGY OF THE MUI IN DISSEMINATING THE UANG PANAI’ FATWA IN SOUTH SULAWESI
Authors: Azka Ibnu , Nida Sairatun , Rizki Agam Muhammad , Baldan Haramain Fathur 
Published: June 2024

<p><em>The understanding that emerges from some Bugis–Makassar people about the meaning of dowry and Uang Panai' is still much wrong. So that it creates a lot of inequality, Uang Panai' is a condition that exceeds the dowry position. Therefore, the Indonesian Ulama Council of South Sulawesi issued a fatwa Uang Panai' to explain the position of Uang Panai' in Islam. This study aims to discuss how the South Sulawesi MUI uses a communication strategy in disseminating fatwa on Uang Panai' in the digital era. The method used in this research is field research with a qualitative descriptive phenomenological approach. The subject of this research is the management of the South Sulawesi Indonesian Ulama Council. Data collection techniques through observation, in-depth interviews and documentation. The main question of this research is how the communication strategy used by the South Sulawesi MUI in disseminating the Uang Panai' fatwa and why the South Sulawesi MUI uses digital media to disseminate the Uang Panai' fatwa. The results of this study indicate that the South Sulawesi MUI is able to accommodate two communication strategies in disseminating the Uang Panai' fatwa in the digital era.</em></p><p class="07AbstrakInggris"> </p>
Exion Math: An Interactive Digital Question Bank Design for Middle School Mathematics
Authors: Ikashaum Fertilia , Wahyuni Sri 
Published: June 2024

Penelitian ini dilatarbelakangi oleh kurangnya kumpulan soal terpadu yang dapat diakses siswa dengan mudah. Bahan ajar yang dimiliki siswa di sekolah tidak dapat memberikan umpan balik berupa skor akhir dan pembahasan dari setiap soal. Terlebih lagi lembar soal yang sering dimiliki siswa memiliki tampilan kurang menarik. Penelitian ini bertujuan untuk menghasilkan bank soal matematika SMP berbasis digital dan interaktif yang valid dan layak digunakan siswa. Bank soal tersebut berupa website yang dapat diakses oleh seluruh siswa tanpa berbayar. Penelitian ini merupakan penelitian design research tipe development study yang terdiri dari preliminary design dan formative evaluation. Data diperoleh melalui angket dan dianalisis menggunakan kategorisasi penilaian. Subjek penelitian terdiri dari dosen, guru, dan siswa sesuai tahap penelitian. Hasil penelitian menunjukkan web bank soal bernilai valid berdasarkan penilaian validator dan dapat digunakan oleh semua kalangan secara terbuka.
A question bank is an accessible website provided for all students free of charge. This study was initiated due to the lack of a accessible collection of integrated questions banks. Teaching materials at school did not provide feedback such as a final score and explanation of each question. Furthermore, the question sheets showed an unattractive interface. This study aimed to produce interactive and digital-based math question banks for junior high school that met the validity and appropriateness for students to use. This design study was a development study encompassing preliminary design and formative evaluation. The data were obtained through questionnaires and analysis using assessment categorization. According to the research stages, the participants were lecturers, teachers, and students. The study results showed that the question bank web was valid based on the validator's assessment and able to be used by all groups openly.
Pre-Service Biology Teachers’ Mathematics Anxiety
Authors: Tamba Kimura Patar , Bermuli Jessica Elfani 
Published: June 2024

Kemampuan kuantitatif dibutuhkan calon guru biologi dalam memahami fenomena biologis. Hal pertama yang perlu dilakukan dalam menyelesaikan masalah ini adalah perlunya eksplorasi kondisi kecemasan matematika calon guru biologi. Penelitian ini bertujuan mengeksplorasi tingkat kecemasan matematika calon guru biologi dan perbedaannya berdasarkan gender dan angkatan masuk kuliah. Data dikumpulkan dengan menggunakan kuisioner AMAS (Abbreviated Math Anxiety Scale). Data dianalisis dengan menggunakan statistic deskriptif, uji anova satu arah, dan uji Kruskal-Wallis. Hasil penelitian menunjukkan calon guru biologi memiliki tingkat kecemasan matematika dan kecemasan belajar matematika berdasarkan angkatan dan gender berada pada kategori sedang. Sementara kecemasan evaluasi matematika berada pada kategori tinggi berdasarkan angkatan dan gender. Hasil penelitian juga menunjukkan tidak terdapat perbedaan kecemasan matematika, kecemasan belajar matematika, kecemasan atas evaluasi matematika berdasarkan gender dan angkatan. Hasil penelitian ini layak menjadi perhatian dalam pendidikan biologi bahwa perlu dikonstruksi suatu desain didaktis ataupun perubahan kurikulum yang mendorong integrasi dan interdisiplinari matematika dan biologi sehingga kecemasan matematika dapat berkurang.
Quantitative ability is needed by prospective biology teachers in understanding biological phenomena. The first thing that needs to be done in solving this problem is the need to explore the condition of pre-service biology teachers’ mathematics anxiety. This study aims to explore the mathematics anxiety level of pre-service biology teachers and their differences by gender and cohort. Data were collected using the AMAS (Abbreviated Math Anxiety Scale) questionnaire. Data were analyzed using descriptive statistics, one-way ANOVA test, and Kruskal-Wallis test. The results showed that pre-service biology teachers had mathematics anxiety levels and mathematics learning anxiety based on cohort and gender were in the medium category. Meanwhile, mathematics evaluation anxiety is in the high category based on cohort and gender. The results also showed that there was no difference between mathematics anxiety, mathematics learning anxiety, anxiety over mathematics evaluation based on gender and cohort. The results of this study deserve attention in biology education that it is necessary to construct a didactic design or curriculum change that encourages integration and interdisciplinary mathematics and biology so that mathematics anxiety can be reduced.
YBM PLN's Strategy in Supporting SDGS through ZIS Potential in Maqashid Syariah Perspective
Authors: Al Mustaqim Dede , Makarrim Alfiyah 
Published: June 2024

Introduction: Yayasan Baitul Maal (YBM) PLN has great potential in managing Zakat, Infaq, and Sadaqah (ZIS) to support Sustainable Development Goals (SDGs) through the economic pillar. Objectives: This research aims to analyze YBM PLN's strategy in supporting SDGs through ZIS from the Maqashid Syariah perspective. Method: This research uses a qualitative method with a case study approach. Primary data was obtained through interviews with YBM PLN administrators and observations of YBM PLN programs in the economic pillar. Secondary data were obtained from YBM PLN documentation and scientific publications related to SDGs and Maqashid Syariah. Results: The results showed that YBM PLN has an effective strategy in managing ZIS to support SDGs through the economic pillar. The YBM PLN program in the economic pillar has proven to be able to empower mustahik and alleviate poverty, which is in line with the goals of SDGs and Maqashid Sharia. YBM PLN plays an important role in supporting SDGs and Maqashid Sharia through effective ZIS management. Implications: This research contributes to science by providing recommendations to improve the effectiveness of YBM PLN's strategy in supporting SDGs.
Determinants of Micro and Small Business Actors on the Motivation to Register for Free Halal Certification in Bondowoso Regency
Authors: Mahendra Hairunnas Esa , Munir Misbahul , Ridlwan Mahmudah 
Published: June 2024

Introduction: Government regulations on halal products, especially in the 2021 Job Creation Law, have been stipulated in the Halal Product Guarantee Law, this is an important factor for producers in the business sector related to halal products, especially since there is a free halal certification program. Objectives: The purpose of this study is to measure the motivation of micro and small business actors in Bondowoso Regency towards registering for free halal certification. Method: This study uses a quantitative approach with multiple linear regression analysis which aims to test the correlation of the variables of Government Regulation (X1), Halal Lifestyle (X2), Perceived Benefits of Halal Certification (X3), Business Competitiveness (X4), Product Safety and Hygiene (X5), to Motivation for Free Halal Certification Registration (Y1). Results: The results showed that government regulations, halal lifestyle, and product safety and hygiene had no significant partial effect on the motivation to register for free halal certification. Meanwhile, the perceived benefits of halal certification and business competitiveness have a partially significant effect on the motivation to register for free halal certification. However, these 5 variables simultaneously affect the motivation to register for free halal certification so it is worthy of being a construct of this study. Implications: The research will provide an overview of the relevant approaches that must be taken to attract micro and small business actors to register for free halal certification.
The Effect of Accountability and Transparency on Interest in Paying Zakat at the National Amil Zakat Agency of Buton Regency With Religiosity as a Moderation
Authors: Amalia Lestari Rezki Nurul , Haliah Haliah , Nirwana Nirwana 
Published: June 2024

Introduction: The Buton Regency National Zakat Amil Agency has the potential to pay zakat by increasing accountability, transparency, and religiosity which can be a factor in advancing the level of community welfare. Objectives: This research aims to determine the effect of accountability and transparency on interest in paying zakat and the relationship between religiosity as moderation in strengthening the influence of accountability and transparency on interest in paying zakat. Method: This research was conducted quantitatively and used a questionnaire as a data collection method. The subjects of this research were 150 muzakki BAZNAS (National Amil Zakat Agency) located in Buton Regency. The data analysis method uses Structural Equation Models with Partial Least Square (PLS). Results: The research results show that accountability and transparency regarding interest in paying zakat have positive and significant results. This research also proves that accountability and transparency on interest in paying zakat are significant with religiosity as a moderating variable that strengthens the influence of accountability and transparency on interest in paying zakat. Implications: These results contribute to the development of a model in research that accounting and transparency in zakat institutions with religiosity as moderation can influence interest in paying zakat.