bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comorbidity of Depression and Diabetes: A Literature Review on Systemic Flaws in Healthcare and the Benefits of Collaborative Diagnosis and Treatment in Primary Care Settings
Authors: Wal Pranay , Kumar Pankaj , Bhardwaj Harsh , Sharma Komal , Tripathi Arpan Kumar , Gupta Arpit , Wal Ankita , Sharma Mukesh Chandra 
Published: May 2024

Background:
The increasing specialization and dispersion of healthcare systems
have led to a shortage of resources to address comorbidities. Patients with coexisting mental
and physical conditions are disadvantaged, as medical providers often only focus on the patient's
mental illness while neglecting their physical needs, resulting in poorer health outcomes.

Objective:
This study aimed to shed light on the systemic flaws in healthcare systems that contribute
to suboptimal health outcomes in individuals with comorbid diseases, including depression
and diabetes. This paper also discusses the clinical and economic benefits of collaborative
methods for diagnosing and treating depressive disorders in primary care settings.

Methods:
A comprehensive literature review of the relationship between depression and diabetes
was conducted. The outcomes of the literature review were carefully analyzed. Several databases
were searched using keywords such as "diabetes," "depression," "comorbidity," "prevalence,"
"epidemiology," and "risk factors" using Google Scholar and PubMed as search engines.
The review and research papers written between 1961 and 2023 were our main focus.

Results:
This study revealed improved depressive symptoms and better blood sugar and blood
pressure control. Additionally, individuals with comorbid depression and diabetes have higher
direct and secondary medical costs. Antidepressants and psychological interventions are equally
effective in treating depressive symptoms in patients with diabetes, although they have conflicting
effects on glycemic control. For individuals with comorbid diabetes and depression,
clear care pathways, including a multidisciplinary team, are essential for achieving the best
medical and mental health outcomes.

Conclusion:
Coordinated healthcare solutions are necessary to reduce the burden of illness and
improve therapeutic outcomes. Numerous pathophysiological mechanisms interact with one
another and may support the comorbidities of T2DM, and depressive disorders could exacerbate
the course of both diseases.
Puerarin Affects 1HMR Spectroscopy Quantified Hepatic Fat Signal Fraction inIntrauterine Growth Restricted Rats
Authors: Wang Tao , Kalonda Mutamba Alpha , Bian Jing , He Xiaori , Bian DuJun 
Published: May 2024

Objective:
This study aimed to investigate the impact of puerarin early intervention on growth parameters and Hepatic Fat Signal Fraction (HFF)
quantification in Intrauterine Growth Restricted (IUGR) rats through Proton Magnetic resonance spectroscopy (1H-MRS).

Methods:
Pregnant rats were divided into three groups: control, IUGR with puerarin treatment, and IUGR without treatment. The treatment and nontreatment
groups were received a low-protein diet during pregnancy, while the control group received a normal diet. After birth, pups in the
treatment group received a unilateral intraperitoneal injection of 50 mg/kg/d puerarin. Male rats were evaluated at 3,8 and 12 weeks, including
measurements of weight, body length and waist circumference and body mass index (BMI). Conventional magnetic resonance imaging and 1HMRS
were conducted using a 3.0 T whole-body MR scanner.

Results:
Newborn pups in the treatment and non-treatment groups showed significantly lower body weight, BMI, and body length at 3 weeks compared to
the control group. However, there were no significant differences in HFF and waist circumference between the three groups at 3 weeks. At 8 and
12 weeks post-delivery, significant differences in body weight, BMI, waist circumference were observed in newborn pups of IUGR non-treatment
rats compared to the control group. In contrast, there were no significant differences in body weight, BMI, waist circumference between the
treatment group and the control group at 8 and 12 weeks. Moreover, the treatment group exhibited notably higher HFF compared to the control
group at both time points. At 12 weeks post-birth, a significant difference in HFF was observed between the IUGR non-treatment and treatment
groups, although no significant difference was found at 8 weeks.

Conclusion:
Early intervention with puerarin following birth has a significant impact on liver fat content and may potentially reduce adult obesity among IUGR
rats.
Development of Autoimmune Hepatitis after COVID-19 Infection in Vaccinated Women
Authors: Lenci Ilaria , Milana Martina , Savino Luca , Signorello Alessandro , Baiocchi Leonardo 
Published: May 2024

Purpose:
SARS-CoV-2 infection has been associated with the impairment of several organs,
including the liver. In addition, cases of autoimmune hepatitis have been described in association
with COVID-19 disease. According to some case reports, vaccination has also been suggested
to elicit the immune liver disorder.

Case Description:
We report on the case series of two middle-aged women developing
COVID-19 infection despite a completed vaccination schedule. More interestingly, the infection
was followed by the onset of acute hepatitis with a significant increase in the values of liver function
tests (x 10 normal values). After ruling out the main causes of liver damage (viral, toxic, etc.),
a diagnosis of autoimmune hepatitis was made and supported by liver histology in both cases. The
clinical picture was quickly reverted with immunosuppressive (steroid) therapy, also confirming
the diagnosis.

Conclusion:
We observed a possible relationship between COVID-19 infection and the onset of
autoimmune hepatitis and also described this occurrence in vaccinated subjects. It remains to be
clarified whether repeated exposure to viral antigens (vaccination plus true infection) or specific
emerging viral genotype (omicron strain) may facilitate the onset of this immune liver disease.
Enhancing Drug Peptide Sequence Prediction Using Multi-view Feature Fusion Learning
Authors: Zhang Junyu , Lu Ronglin , Zhou Hongmei , Jiang Xinbo 
Published: May 2024

Background:
Currently, various types of peptides have broad implications for human
health and disease. Some drug peptides play significant roles in sensory science, drug research, and
cancer biology. The prediction and classification of peptide sequences are of significant importance
to various industries. However, predicting peptide sequences through biological experiments is a
time-consuming and expensive process. Moreover, the task of protein sequence classification and
prediction faces challenges due to the high dimensionality, nonlinearity, and irregularity of protein
sequence data, along with the presence of numerous unknown or unlabeled protein sequences.
Therefore, an accurate and efficient method for predicting peptide category is necessary.

Methods:
In our work, we used two pre-trained models to extract sequence features, TextCNN
(Convolutional Neural Networks for Text Classification) and Transformer. We extracted the overall
semantic information of the sequences using Transformer Encoder and extracted the local semantic
information between sequences using TextCNN and concatenated them into a new feature. Finally,
we used the concatenated feature for classification prediction. To validate this approach, we conducted
experiments on the BP dataset, THP dataset and DPP-IV dataset and compared them with
some pre-trained models.

Results:
Since TextCNN and Transformer Encoder extract features from different perspectives, the
concatenated feature contains multi-view information, which improves the accuracy of the peptide
predictor.

Conclusion:
Ultimately, our model demonstrated superior metrics, highlighting its efficacy in peptide
sequence prediction and classification.
Deep Learning based Feed Forward Neural Network Models for Hyperspectral Image Classification
Authors: Jeya I Jasmine Selvakumari , J Jaya 
Published: May 2024

Introduction
Traditional feed-forward neural networks (FFNN) have been widely used in image processing, but their effectiveness can be limited. To address this, we develop two deep learning models based on FFNN: the deep backpropagation neural network classifier (DBPNN) and the deep radial basis function neural network classifier (DRBFNN), integrating convolutional layers for feature extraction.

Methods
We apply a training algorithm to the deep, dense layers of both classifiers, optimizing their layer structures for improved classification accuracy across various hyperspectral datasets. Testing is conducted on datasets including Indian Pine, University of Pavia, Kennedy Space Centre, and Salinas, validating the effectiveness of our approach in feature extraction and noise reduction.

Results
Our experiments demonstrate the superior performance of the DBPNN and DRBFNN classifiers compared to previous methods. We report enhanced classification accuracy, reduced mean square error, shorter training times, and fewer epochs required for convergence across all tested hyperspectral datasets.

Conclusion
The results underscore the efficacy of deep learning feed-forward classifiers in hyperspectral image processing. By leveraging convolutional layers, the DBPNN and DRBFNN models exhibit promising capabilities in feature extraction and noise reduction, surpassing the performance of conventional classifiers. These findings highlight the potential of our approach to advance hyperspectral image classification tasks.
Novel Energy-efficient Modified LEACH Routing Protocol for Wireless Sensor Networks
Authors: Dongare Mahendra Prabhakar , Jondhale Satish Raosaheb , Agarkar Balasaheb Shrirangrao 
Published: May 2024

Introduction:
In wireless sensor networks (WSNs), hierarchical clustered routing protocols
play a crucial role in minimizing energy consumption. The Low Energy Adaptive Clustering
Hierarchy (LEACH) architecture is commonly employed for application-specific protocols in
WSNs. However, the LEACH protocol may lead to increased energy consumption within the network
if the rotational distribution of cluster heads (CHs) is not considered.

Methods:
A novel average energy, residual energy-based modified LEACH (aerem-LEACH) routing
protocol for improving the WSN’s energy efficiency is proposed. This approach simultaneously
considers the average energy of the networks and the residual node energy for routing, thereby
reducing overall power consumption.

Results:
The suggested approach in aerem-LEACH accounts for optimal CHs numbers, and nodes
in close proximity to the sink are forbidden from participating in cluster formation in order to
achieve sufficient performance in the form of reduced sensor node energy consumption. Furthermore,
a new threshold is employed in the proposed approach for selecting CHs for the network,
and the aerem-LEACH uses free space, multiple hopping, and a hybrid communicating model for
an energy-efficient network.

Conclusion:
The simulation result demonstrates that there is a substantial reduction in the consumption
of energy in WSNs with the proposed aerem-LEACH routing protocol compared with
existing routing protocols, namely Stable Energy Efficient Network (SEEN), Energy Efficient
LEACH (EE LEACH), Optical LEACH (O-LEACH), LEACH-Mobile (LEACH-M), LEACHCentralized
(LEACH-C), and LEACH for small-scale as well as large-scale sensor field.
The Development of Tavern Legislation during the Preparation of the wine Reform of 1863 in Russia
Authors: Goryushkina N. E. 
Published: May 2024

Relevance. The wine reform of 1863 is an important stage in the improvement of Russian legislation on the tavern industry. But the activities of the Special Committee for the Development of tavern legislation in historiography have not received adequate coverage. The problem raised in the article is very relevant for the correct interpretation of the history of tavern establishments. The purpose is to show the activities of a Special Committee headed by A.P. Zablotsky-Desyatovsky on the development of tavern legislation in Russia.The objectives arising from the designated goal are to ensure that: to describe the state of the tavern industry on the eve of the wine reform; to reveal the course of preparation of the "Regulations on the tavern industry"; to highlight the requirements legally imposed on tavern establishments.The methodology of the article includes the principles of objectivity, historicism and consistency, which complemented the historical-chronological, historical-comparative research methods.Results. There was no general legislation regulating the activities of tavern establishments in Russia for a long time, different laws regulated the tavern industry in capitals, port, provincial, and county towns. They were extensive, confusing, and hampered the initiative of the hotel owners, but left many aspects of the activity without instructions. The government has been developing tavern legislation for a long time. The merit in the creation of the all-Russian "Regulations on tavern establishments" belongs to a Special commission under the leadership of A.P. Zablotsky-Desyatovsky. She carried out this work as part of the preparation of the wine reform. The "Regulations on tavern establishments" became the fundamental document that defined the conditions and nature of the tavern business for several decades.Conclusion. The "Regulations on Tavern Establishments", highly approved on July 4, 1861, corresponded to the spirit of the times. It made it possible to establish clear rules for the functioning of tavern establishments. Their number increased significantly in the second half of the XIX century, budget revenues from taverns became a prominent part of budgets at all levels.
The Attitude of the Political Parties of the Russian Empire to the War With Austria-Hungary and Germany in 1914
Authors: Viziltir E. V. 
Published: May 2024

Relevance. The war that began in 1914 met the growing needs of the bourgeoisie class, as it was a source of enormous profits. In the event of a victory, Russia would gain exclusive dominance over the Black Sea, Asia Minor and the Balkan Peninsula. The war was also supposed to serve as a lightning rod against the growing revolutionary movement and the impending revolution. On the eve of the war, the labor movement in Russia reached exceptional tension, in its scope it was comparable to the revolutionary year 1905. In such circumstances, the war was supposed to "extinguish" the growing discontent of the people. The study of the attitude of political parties in the Russian Empire to the war is of not only theoretical but also practical interest, since the possibilities of preventing a new world war are largely related to the position of various social forces, political parties, the state of civil society, and the ability to negotiate controversial issues.Purpose. To investigate the attitude of the political parties of the Russian Empire to the outbreak of the First World War in 1914.Objectives: to analyze the political situation in the country by 1914 and characterize the positions of Russian political parties in their attitude to the war.Methodology. The author's methodology is based on the principles of historicism and objectivity. The methods of information synthesis and analysis, the method of generalization of the obtained data, and the ideographic method are also used.Results. In the study, the author shows the process of unification of Russian political parties in relation to the war with Austria-Hungary and Germany that began in 1914. At that moment, all party barriers fell, and representatives of political parties recognized the need for a war to a victorious end. But the Mensheviks and Trudoviks opposed war loans, and the Bolsheviks protested against the war.Conclusion. An analysis of the sources showed that the war consolidated Russian society. Representatives of all parties, except the Social Democrats, supported Russia's participation in the war, considering it defensive.
Legal Regulation of Monastic Usury in Russia in the XV-XVII Centuries
Authors: Kuzmin M. O. 
Published: May 2024

Relevance. This article examines the problems of normative regulation of monastic usury in Russia in the Middle Ages and Modern era. Due to the peculiarities of economic and social development and historical and political reasons, the Church for a long time carried out operations characteristic of specialized credit and banking organizations. However, such activities contradicted basic Christian principles and the texts of the Holy Scriptures, prompting the legislator to respond to the current situation by creating various legal acts. The study of this issue by Soviet scientists through the prism of anti-religious policy in the modern period cannot reflect the full objectivity of this phenomenon. Consideration of monasteries as a unique subject of civil legal relations in the XV-XVII centuries will allow us to rethink the degree of development of financial in the Russia.The purpose of the research is to form a modern scientific approach to the legal regulation of monetary and borrowing activities of monasteries in Russia.Objectives: to determine the place of monastic usury in the financial sphere of the Russia; to characterize the main mechanisms of interaction between the Church and other subjects of civil legal relation in the field of loan transactions; to identify the features of normative regulation of this phenomenon.The research methodology is characterized by the application of the principles of historicism and objectivity, as well as structural-functional, formal-legal and comparative-legal methods.The results of the research indicate the versatility of the problems posed, have a historical and legal nature and allow us to consider the participation of monasteries in credit transactions from the perspective of economic and legal views for further scrutiny.The conclusions formulated based on the results of the study confirm the existence of complexly structured monetary-borrowing relations in the Russia in the 15th-17th centuries and their special legal regulation. The article is a continuation of the author’s scientific research on issues of legal regulation of credit and banking relations in the history of Russia.
Prenuptial Agreement and Agreement on the Division of Common Property of Spouses (former Spouses) Through the Prism of Intersectoral Private law Regulation of Property Relations in Russia
Authors: Shershen T. V. 
Published: May 2024

Relevance. The most acute problems of modern Russian legislation, theory and law enforcement practice include the inconsistency of private law norms designed to regulate property relations with the participation of subjects of civil and family law – spouses and former spouses, creditors of the debtor spouse and other persons, whose rights and interests may be violated as a result of unscrupulous behavior of a participant in civil turnover, abuse granted contractual freedom. The common joint property of the spouses forms the material basis of the family. The increase in cases of challenging marriage contracts and agreements on the division of marital property in bankruptcy proceedings and especially consumer bankruptcy confirms the need to resolve the issue of coordinating the intersectoral interaction of family law and civil law in the field of property relations of subjects of civil and family law.The purpose of the study is to develop theoretical provisions on the nature of the interaction of the norms of civil and family law governing the property relations of subjects of civil and family law.Objectives: to identify the "pain points" of intersectoral regulation of property relations with the participation of subjects of family law (spouses and former spouses); to propose possible solutions to the problem of regulating property relations with the participation of a debtor spouse (former debtor spouse) and a creditor (creditors).Methodology. In the course of the research, a systematic method, analysis and synthesis, and a formal legal method were applied.The results of the study are theoretical and applied in nature, aimed at improving the quality of legal intersectoral regulation of property relations involving spouses (former spouses).The conclusions reached by the author in the course of the research are of a debatable nature and do not pretend to be the only correct solution to the situation. The article is a continuation of the study of the issues of intersectoral contractual regulation of subjects of family law
Private Life, Personal Secret or Personal Data: How to Interpret Information about the Person to the Law Enforcement Officer?
Authors: Alikhadzhiyev I. S. 
Published: May 2024

Relevance of the article is determined by considering the problem of interpreting the relationship between personal data and information about the private life of a person constituting his secret for the purpose of uniform law enforcement. Particular attention is paid to the position of the Constitutional and Supreme Courts of the Russian Federation, which have formed the practice of interpretation by courts of general jurisdiction of the concepts of private life and personal secrecy.The purpose of the study is to supplement the theory of criminal law with new knowledge about the criteria for delimiting the terms under consideration, taking into account their difference and the qualification of crimes that encroach on the inviolability of privacy, personal secrets and personal data to effectively counter them.Objectives: on the basis of the established positions of theorists and investigative and judicial practice, distinguish between the concepts under consideration and propose recommendations regarding a criminal law assessment of acts committed in relation to privacy and personal data.Methodology. The research methodology is represented by general scientific and private scientific methods of knowing objective reality. Methods of analysis, synthesis, induction, deduction, as well as system-analytical, formallegal, formal-logical and documentary methods found their application in the work.The results of the study are of a theoretical and applied nature and include the development of recommendations for the law enforcement officer regarding the assessment of the presence of evidence of corpus delicti that encroached on privacy, personal secrets or personal data. The specific examples show the formal interpretation of the extinguished or withdrawn criminal record as personal data in its legal absence. To ensure the balance of private and public interests, a different approach to understanding criminal records as a personal secret in the event of its repayment or removal is justified.Conclusion. In law enforcement practice, there are no clear criteria for delineation, in which case private life, personal secrecy, and in which personal data are protected by means of criminal law. The proposal to introduce independent responsibility for illegal actions with personal data, which may not necessarily be information constituting privacy or personal secrets, is supported.