bluuebunny/crossref_metadata_2025_split huggingface dataset:
Niger : Troubles neuropsychiques révélant un syndrome de Fahr chez un sujet de 29 ans : à propos d’un cas dans le service de psychiatrie de l’hôpital national de Niamey
Authors: Douma Maiga Djibo , Sani Aminou , Salifou Abdou Moubarack M , Amadou Sidikou 
Published: April 2024

le syndrome de Fahr est caractérisé par des calcifications isolées bilatérales et symétriques des ganglions de la base du cerveau. Le polymorphisme de ces manifestations cliniques rend difficile le diagnostic. Nous rapportons le cas d’un patient de 29 présentant un syndrome de Fahr révélé par des troubles neuropsychiques évoluant depuis 7 ans et dont la tomographie cérébrale a permis le diagnostic. Des manifestations neuropsychiques d’installation et d’évolution lentes chez un sujet jeune imposent la prescription d’un bilan biologique en première intention comprenant au moins une calcémie avant toute prescription de médicaments psychotropes.
France : Le don et l’amour en psychanalyse
Authors: Djilali-Messaoud Fatiha 
Published: April 2024

nous tenterons dans ce travail de montrer que le désir consiste à convoiter ce que l’on n’a pas tandis que l’amour lui, consiste à donner ce que l’on n’a pas. L’aimant désire le rien de l’aimé qui devient aimant en lui concédant ce rien. Les cas cliniques de Freud : Dora et L’Homme aux rats nous serviront avec Le Banquet de Platon de supports réflexifs.
Le chien noir de la mélancolie – Les Murray
Authors: Padovani Pascal 
Published: April 2024

Ce travail est issu d’une question à laquelle j’ai tenté de répondre. Les Murray, immense poète australien méconnu en France, est-il, comme l’affirme Daniel Tammet qui a traduit en français certains de ses poèmes, un autiste ? Pour répondre à cette question, j’ai dû aller y voir de plus près et explorer les multiples facettes de sa vie et de son œuvre : son œuvre écrite d’abord, mais aussi ses nombreuses lectures publiques et quantité d’interviews qu’il a données dans divers médias. Au fil de ce parcours il s’est formé en moi la conviction que Les Murray est bien davantage un cas de mélancolie, et ainsi constitue un témoignage de premier ordre sur cette terrible maladie. J’ai alors pu préciser certains de ses aspects : douleur d’exister, rapport au corps, mésaventures du désir, et enfin la suppléance trouvée dans l’écriture : un corps perpétuel de poésie.
Des avancées paradoxales
Authors: Durovic Anja 
Published: April 2024

Même si les inégalités de genre dans les niveaux de participation politique ont évolué au fil du temps, elles paraissent plus que jamais différenciées et dépendantes des modes d’action. Comment expliquer cette évolution inégale des niveaux de participation politique entre les femmes et les hommes en France ? Cette étude propose un cadrage théorique nouveau et s’appuie sur une approche empirique doublement comparative en analysant différents types d’engagement politique et en suivant des cohortes de naissances au fil du temps, prenant appui sur trois grandes enquêtes longitudinales : l’enquête européenne sur les valeurs (1981-2017), l’enquête sociale européenne (2002-2018) ainsi que les enquêtes sur la participation électorale de l’Insee (2002-2017).
La liturgie, pédagogie de la synodalité
Authors: Souletie Jean-Louis 
Published: April 2024

La synodalité comme la liturgie sont toutes deux de nature pneumatologique : elles sont animées par l’Esprit Saint et manifestent la nature et la mission de l’Église. L’auteur souligne combien la diversité et la complémentarité des dons de l’Esprit dans la vie de l’Église sont essentielles pour la vie liturgique, comme pour la synodalité, permettant à tous les membres de constituer le corps du Christ, chacun à sa juste place. « Membres les uns des autres, selon la métaphore paulinienne, les baptisés sont des dons organiquement liés entre eux pour la mission de tout le corps. » La spécificité de la liturgie, qui exprime la totalité du mystère chrétien, est qu’elle est « une sorte de bain ecclésial dans lequel se renouvelle en permanence l’incorporation des fidèles dans la vie de l’Église », contribuant et favorisant ainsi la synodalité en son sein. Avec la liturgie, les fidèles apprennent à faire corps avec d’autres, comme dans la synodalité qui leur apprend à discerner ensemble l’appel de Dieu. Par leur caractère pneumatologique, liturgie et synodalité constituent une forme de vie ecclésiale dans la communion et la participation, ordonnée à la mission.
Culture d’origine et figure auctoriale dans les œuvres de François Cheng
Authors: Yang Xiaoliu 
Published: April 2024

L’écrivain francophone d’origine chinoise François Cheng, écrivain migrant en France, connaît aujourd’hui une forte reconnaissance auprès du lectorat français. Il a pourtant subi avant sa notoriété, pendant une longue période, une crise identitaire à cause des expériences d’errance après son arrivée dans ce pays d’accueil. Pris dans la confrontation entre deux cultures hétérogènes, la culture chinoise et la culture française, il a réussi à construire une identité transculturelle bien spécifique et à présenter l’image d’un homme de dialogue, un « pèlerin » entre l’Orient et l’Occident, en ne cessant d’avoir recours à la culture et à la pensée chinoises dans ses créations littéraires. Cet auteur au parcours emblématique et contrasté (auteur en exil et figure de réussite) nous invite à étudier le rapport entre ses expériences identitaires, sa mobilisation de la culture chinoise et la figure auctoriale qu’il souhaite présenter de lui-même.
Le baiser de Satan : lecture de Bernanos
Authors: Falque Emmanuel 
Published: April 2024

On voudrait vivre « sous le soleil de Dieu » (Ecc. 8,15), mais on se découvre Sous le soleil de Satan . Nul plus que Bernanos ne l’a vu, et aussi ne l’a su – car la littérature atteint ce que ni la philosophie ni la théologie ne savent dire, en particulier pour ce qui est du tourment du mal. Caché sous la figure du « maquignon picard », et donc d’un homme ordinaire, le diable ne se laisse pas voir ; il aime plutôt à se déguiser. Il n’y a pas le mal d’un côté et le bien de l’autre chez Bernanos, mais plutôt « le mal sous la figure du bien ». Telle est sa suprême ruse, et aussi sa plus sûre manière de nous percer à jour. Brouillant les frontières, se faisant passer pour personne alors qu’il est quelqu’un, préférant le « Froid » de la glace au chaud des flammes, et (se) couchant avec l’abbé Donissan pour lui ôter son souffle, Satan nous guette toujours – moins pour se montrer que pour nous piéger. Une « lecture philosophique » de ces pages fulgurantes de Sous le soleil de Satan (rencontre de l’abbé Donissan avec le maquignon picard) élèvera Bernanos au rang des plus grands penseurs catholiques. Nul n’en avait douté. Mais le lire, et le relire, permet de le confirmer.
« Greffer la Parole biblique sur la durée d’une vie ». Petite théologie de la poésie des Psaumes
Authors: Oiry Béatrice 
Published: April 2024

Dans son essai Marcher dans la neige , le poète Jean-Pierre Lemaire utilise la métaphore de la greffe pour parler de l’usage que le poète croyant peut faire des Écritures bibliques dans le poème. Il insiste sur la double temporalité spécifique à ce recours : il s’agit de greffer la parole divine dont l’efficacité est immédiate au cours long et lent des existences humaines sans que celui-ci s’en trouve aboli ou méprisé. Cette perspective n’est pas sans évoquer les expériences de foi dont témoignent les psaumes. Une attention à la forme spécifique des vers de la poésie hébraïque permet de dégager la manière dont la dynamique propre au poème est au service de l’élaboration de l’expérience spirituelle. Les psaumes de supplication – et en particulier le Ps 22 – font entendre les modalités selon lesquelles la Parole se greffe à l’expérience du suppliant. Et il faut toute la longueur de l’épreuve pour que la greffe, sous la modalité souvent paradoxale d’une parole silencieuse, soit accueillie comme énonciation vitale.
Etiologies and Seizure Outcome of Neonatal Seizures: A Tertiary University Hospital Experience
Authors: Muthaffar Osama Y. , Aldail Abdullah A. , Khojah Imad M. , Alyazidi Anas S. , Alotibi Taif K. , Makki Lama T. 
Published: April 2024

Context:
Despite the vast developments in medical sciences in recent decades, seizures remain a common occurrence among neonates, associated with high rates of morbidity and mortality.

Aims:
The aim of this study was to assess and analyze the presentation and outcome of neonates who were previously exposed to seizures.

Subjects and Methods:
Following a retrospective research design, this study included 50 cases of neonatal seizures (29 males and 21 females), who were admitted to the neonatal intensive care unit at King Abdulaziz University Hospital, Jeddah City, Saudi Arabia. Data were collected from the hospital records and included all visits between January 2022 and December 2022.

Results:
The most common types of neonatal seizures were clonic and myoclonic seizures (44% and 28%, respectively). Apgar score at 5 min was <7 in 30% of cases. The main diagnosis was hypoxic-ischemic encephalopathy (HIE) in 28 children (56%), and central nervous system (CNS) infection in 18 children (36%). Children with neonatal seizures mainly received phenobarbital, benzodiazepines, or levetiracetam (48%, 46%, and 36%, respectively). Mechanical ventilation was applied to 20 children (40%). A total of 15 children (30%) had developmental delays, being global delay in 7 children (14%), or motor in 8 children (16%), while 6 children died (12%). Seizures could be controlled in 37 children (74%). Children who presented early (during the 1st week of life) and those who had Apgar scores <7 at 5 min had significantly worse outcomes, with higher case fatality and less seizure control than those who had Apgar scores of 7–10 (P < 0.001).

Conclusions:
Seizures are a common occurrence among neonates, especially males during the 1st week of their lives. HIE and CNS infections are the main diagnoses. The most administered medications are phenobarbital, benzodiazepines, and levetiracetam. Children who present during their 1st week of life and those who have 5-min Apgar scores <7 have significantly higher case fatality and less seizure control.
The role of ultra-widefield imaging with navigated central and peripheral cross-sectional and three-dimensional swept source optical coherence tomography in ophthalmology: Clinical applications
Authors: Stanga Paulo E. , Valentín-Bravo Francisco J. , Reinstein Ursula I. , Saladino Andrea , Arrigo Alessandro , Stanga Sebastian E. F. 
Published: April 2024

PURPOSE:
To assess central and peripheral retinal and choroidal diseases using ultra-widefield (UWF) fundus imaging in combination with navigated central and peripheral cross-sectional and three-dimensional (3D) swept source optical coherence tomography (SS-OCT) scans.

METHODS:
Retrospective study involving 332 consecutive patients, with a nearly equal distribution of males and females. The mean age of patients was 52 years (range 18–92 years). Average refractive error was −3.80 D (range +7.75 to −20.75 D).

RESULTS:
The observations in this study demonstrate the efficacy of peripheral navigated SS-OCT in assessing various ocular conditions. The technology provides high-quality images of the peripheral vitreous, vitreoretinal interface, retina, and choroid, enabling visualization of vitreous floaters and opacities, retinal holes and tears, pigmented lesions, and peripheral retinal degenerations. 3D OCT scans enhance the visualization of these abnormalities and improve diagnostic and therapeutic decisions.

CONCLUSION:
Navigated central and peripheral cross-sectional and 3D SS-OCT scans offer significant complementary benefits in the assessment and management of retinal diseases. Their addition to UWF imaging provides a comprehensive view of central and peripheral ocular structures, aiding in early detection, precise anatomical measurements, and objective monitoring of disease progression. In addition, this technology serves as a valuable tool for patient education, a teaching tool for trainees, and documentation for medico-legal purposes.
Presumed macular toxicity of high-dose intravitreal ganciclovir
Authors: Sweta Shubhra , Prabhakaran Parvathy , Kakunje Chaithra , Sagar Pradeep , Biswal Suchitra , Ravishankar H. N. 
Published: April 2024

Abstract:
A 56-year-old male with bilateral cytomegalovirus retinitis was initiated on oral valganciclovir and intravitreal ganciclovir injection twice a week in first 2 weeks and once a week in subsequent weeks. An intravitreal dose of 2 mg/0.08 mL was administered in the 1st week. Considering the suboptimal response, the dose of intravitreal ganciclovir was increased to 4 mg/0.08 mL. After 4 weeks of therapy (four doses of 4-mg ganciclovir), the patient complained of worsening of vision. Fundus examination showed resolving retinitis, but the optical coherence tomography (OCT) showed neurosensory detachment (NSD) at the fovea in both eyes with inner retinal hyperreflectivity in the right eye. Considering the possibility of retinitis involving fovea, a higher dose of intravitreal ganciclovir (6 mg/0.08 mL) was administered. The patient reported further worsening of vision immediately after removing the eye patch 2 hr following the injection. OCT showed a full-thickness hyperreflective vertical band with ellipsoid zone disruption at the fovea and inner retinal hyperreflectivity in the right eye. Hyperreflective vertical band with NSD was seen in the left eye. A possibility of macular toxicity due to intravitreal ganciclovir was considered. Intravitreal therapy was stopped and oral valganciclovir was continued. At 1-month follow-up, the patient reported improvement in vision. The hyperreflectivity and NSD were resolved at month follow-up. Although higher doses of ganciclovir up to 6 mg have been used in the past, it would be better to avoid higher doses considering the development of presumed drug toxicity in our case following the use of 4 mg and 6 mg.
Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicine
Authors: Rajput Shafiqa Naeem , Naeem Bushra Kiran , Ali Anwar , Salim Asmat , Khan Irfan 
Published: April 2024

BACKGROUND
Stem cells are undifferentiated cells that possess the potential for self-renewal with the capacity to differentiate into multiple lineages. In humans, their limited numbers pose a challenge in fulfilling the necessary demands for the regeneration and repair of damaged tissues or organs. Studies suggested that mesenchymal stem cells (MSCs), necessary for repair and regeneration via transplantation, require doses ranging from 10 to 400 million cells. Furthermore, the limited expansion of MSCs restricts their therapeutic application.
AIM
To optimize a novel protocol to achieve qualitative and quantitative expansion of MSCs to reach the targeted number of cells for cellular transplantation and minimize the limitations in stem cell therapy protocols.
METHODS
Human umbilical cord (hUC) tissue derived MSCs were obtained and re-cultured. These cultured cells were subjected to the following evaluation procedures: Immunophenotyping, immunocytochemical staining, trilineage differentiation, population doubling time and number, gene expression markers for proliferation, cell cycle progression, senescence-associated β-galactosidase assay, human telomerase reverse transcriptase (hTERT) expression, mycoplasma, cytomegalovirus and endotoxin detection.
RESULTS
Analysis of pluripotent gene markers Oct4 , Sox2 , and Nanog in recultured hUC-MSC revealed no significant differences. The immunophenotypic markers CD90, CD73, CD105, CD44, vimentin, CD29, Stro-1, and Lin28 were positively expressed by these recultured expanded MSCs, and were found negative for CD34, CD11b, CD19, CD45, and HLA-DR. The recultured hUC-MSC population continued to expand through passage 15. Proliferative gene expression of Pax6 , BMP2 , and TGFb1 showed no significant variation between recultured hUC-MSC groups. Nevertheless, a significant increase (P < 0.001) in the mitotic phase of the cell cycle was observed in recultured hUC-MSCs. Cellular senescence markers (hTERT expression and β-galactosidase activity) did not show any negative effect on recultured hUC-MSCs. Additionally, quality control assessments consistently confirmed the absence of mycoplasma, cytomegalovirus, and endotoxin contamination.
CONCLUSION
This study proposes the development of a novel protocol for efficiently expanding stem cell population. This would address the growing demand for larger stem cell doses needed for cellular transplantation and will significantly improve the feasibility of stem cell based therapies.
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages
Authors: Almahasneh Fatimah , Abu-El-Rub Ejlal , Khasawneh Ramada R , Almazari Rawan 
Published: April 2024

BACKGROUND
Mesenchymal stem cells (MSCs) have been extensively studied for therapeutic potential, due to their regenerative and immunomodulatory properties. Serial passage and stress factors may affect the biological characteristics of MSCs, but the details of these effects have not been recognized yet.
AIM
To investigate the effects of stress factors (high glucose and severe hypoxia) on the biological characteristics of MSCs at different passages, in order to optimize the therapeutic applications of MSCs.
METHODS
In this study, we investigated the impact of two stress conditions; severe hypoxia and high glucose on human adipose-tissue derived MSCs (hAD-MSCs) at passages 6 (P6), P8, and P10. Proliferation, senescence and apoptosis were evaluated measuring WST-1, senescence-associated beta-galactosidase, and annexin V, respectively.
RESULTS
Cells at P6 showed decreased proliferation and increased apoptosis under conditions of high glucose and hypoxia compared to control, while the extent of senescence did not change significantly under stress conditions. At P8 hAD-MSCs cultured in stress conditions had a significant decrease in proliferation and apoptosis and a significant increase in senescence compared to counterpart cells at P6. Cells cultured in high glucose at P10 had lower proliferation and higher senescence than their counterparts in the previous passage, while no change in apoptosis was observed. On the other hand, MSCs cultured under hypoxia showed decreased senescence, increased apoptosis and no significant change in proliferation when compared to the same conditions at P8.
CONCLUSION
These results indicate that stress factors had distinct effects on the biological processes of MSCs at different passages, and suggest that senescence may be a protective mechanism for MSCs to survive under stress conditions at higher passage numbers.
Strategi Komunikasi Jurnalis Perempuan Dalam Peliputan Kasus Kekerasan Seksual Terhadap Perempuan Di Kota Padang
Authors: Rahmadani Rina , Flowerina Indria 
Published: April 2024

The term sexual violence is not a new term in Indonesia because this type of violence occurs almost every year in the country. News about this issue demands social empathy. Therefore, journalists need to be careful in investigating sexual violence cases because journalism ethics need to be applicable in digging up information and collecting news to be analyzed and to be reported to the public. The purpose of this research is to find out how female journalists applied communication strategies in investigating sexual violence cases towards women. This research uses a qualitative approach, in the form of a case study, and its data collection techniques are in-depth interview, observation, and documentation. Data analysis techniques are data reduction, data display, and conclusion remarks. The theory used in data analysis was the Social Penetration Theory. This theory refers to interpersonal relationships. According to Irwin Altman and Dalmas Taylor, social penetration theory illustrates the process of relationship ties between individuals that move from a superficial level of communication to the most complex level of communication. The result of this research explains that the communication strategy of female journalists in investigating sexual violence towards women is related to the application of feeling empathy, listening attentively, being open to knowing different views, and holding an even better relationship with the person being investigated for the news.
ЗАМАНАУИ ҚАЗАҚ ХОРЕОГРАФИЯСЫНДАҒЫ МЕТАМОДЕРННІҢ КӨРКЕМ КӨРІНІСТЕРІ
Authors: Кукетов Берик , Шанкибаева Алия 
Published: April 2024

ХХІ ғасырдағы ұлттық өнердің дамуы оның мазмұнын ашудың жаңа жолдарын іздестіруде. Бұл құбылыс хореографиялық өнерге де өз ықпалын тигізуде. Өзінің формасы мен мазмұны жағынан жаңашылдығымен ерекшеленетін жарқын хореографиялық қойылымдар пайда болған ХХ ғасырдың ІІ-жартысынан кейінгі даму кезеңдеріндегі ұлттық бидің қойылымдарын талдай отырып, авторлар қазіргі кезеңде қазақ сахналық биі қойылымның мазмұнын ашуда жаңа көзқарасқа ие болуда, ол өз кезегінде би қимылдарын сахнада көрсетудің жаңа формасын талап етеді деген қорытындыға келді.Мақалада З. Райбаевтың «Фрескалар» балеті (1981) ұлттық би мен классикалық хореография синтезінің жаңа түрін дамытуға ықпал еткен алғашқы жарқын туынды ретінде атап өтіледі. Мақалада постмодернизм кезеңіндегі ұлттық хореографияның даму жолы қарастырылып, оның сипаттамасы беріліп, одан әрі қазіргі кезеңдегі би өнерінің дамуы жан-жақты зерттеледі. Көптеген заманауи туындыларды зерттеу барысында би мазмұнын кейіпкердің күйін дәлірек жеткізуге ықпал ететін өзгертілген пластикалық қозғалыстар арқылы көрсету үрдісі байқалады.Қазіргі уақытта жас хореографтар заманауи технологияларды пайдалана отырып, ұлттықхореографияда тарихи оқиғаларды ұсынудың бірегей авторлық тәсілдерін енгізіп, сол арқылыұлттық биді байытып, оның одан әрі дамуына үлес қосуда. Бұл, өз кезегінде, метамодернизмніңтенденцияларының пәнаралық дискурста орынды деп танылуға ұмтылатын жаңа әдіс ретінде ашылуына әкелді. Метамодернизм кезеңіндегі ұлттық хореография зерттеулері жоқтың қасы, соның нәтижесінде, осы жұмыста дамудың сабақтас салаларының нәтижелері мен тәжірибелеріне сүйене отырып, қорытындылар жасалды. Ұлттық хореография академиясының ғылымизертханасының теориялық және педагогикалық еңбектеріне шолу жасалды. Зерттеу жұмысындаұлттық хореографияның заманауи қойылымдарын талдау қазақ би өнеріндегі метамодернизм тенденцияларының көрінісін анықтауға мүмкіндік берді.Қорытындылай келе, зерттеудің негізгі мақсаты – қазақ хореография өнеріндегі метамодерннің көркем көріністерін анықтап, ашып көрсету үшін келесі ғылыми әдістер қолданылды: диахронологиялық, аналитикалық талдау, салыстыру, бақылау.