bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical, radiographic, and aesthetic outcomes at two narrow‐diameter implants to replace congenital missing maxillary lateral incisors: A 3‐year prospective, clinical study
Authors: Roccuzzo Andrea , Imber Jean‐Claude , Lempert Jakob , Jensen Simon Storgård 
Published: June 2024

AbstractIntroductionTo present the 3‐year clinical, radiographic, and aesthetic outcomes in patients with congenitally missing lateral incisors rehabilitated with two narrow‐diameter implants (NDIs).MethodsThe original population consisted of 100 patients rehabilitated with a cement‐retained bi‐layered zirconia single‐unit crown supported by either a Ø2.9 mm (Test) or a Ø3.3 mm (Control) NDI (n = 50). At the 1‐ and 3‐year follow‐up (T2, T3), implant survival rate, crestal bone level (CBL) changes, biological, and technical complications were recorded, while the assessment of the aesthetic outcomes was performed using the Copenhagen Index Score.ResultsSeventy‐four patients Ø2.9 mm (n = 39) or Ø3.3 mm (n = 35) reached T3, as 24 patients were lost to follow‐up and 1 implant (Ø3.3 mm) was removed. Throughout the observation period, minimal CBL changes (i.e., <1 mm) were detected between groups. Despite the positive aesthetic scores recorded (i.e., 1–2), at T3 20% of patients rehabilitated with a Ø3.3 mm versus 2.6% of patients Ø2.9 mm displayed an alveolar process deficiency (Score 3). No additional technical and/or mechanical complications were recorded between T2 and T3. Tooth vitality was maintained in all neighboring teeth. Peri‐implant probing depths and plaque scores remained low in both groups (p > 0.05).ConclusionThe use of 2.9 or 3.3 diameter implants showed comparable favorable mid‐term results in terms of survival rate, CBL, and aesthetic outcomes. Hence, clinicians should rely on the use of such NDIs when replacing maxillary lateral incisors.
Public speaking and leadership in implant dentistry: Have these skills been overlooked?
Authors: Paterno’ Holtzman Lucrezia , Pitta João , Milinković Iva , Pirc Miha , Romandini Pierluigi , Alexopoulou Maria‐Angeliki , Becker Kathrin , Feher Balazs , Makarov Nikolay , Scarlat Pavel , Sanz‐Sánchez Ignacio 
Published: June 2024

AbstractObjectiveTo describe the speaker and leadership development seminars during the 2023 EAO Summer Camp (SC).Materials and MethodsIn September 2023, 24 participants joined the SC organized by the EAO Junior Committee (JC) in Lisbon, focused on enhancing public speaking and leadership skills. Facilitated by two experienced trainers, the program aimed to evaluate the participants' progress through pre‐, post‐training “immediate” and “delayed” (3 months after the event) anonymous questionnaires. The JC formulated a survey (JCS) addressing aspects of public speaking, presentation skills and leadership, how important the participants considered them and what type of training in this field they had received thus far.ResultsTwenty‐three participants responded to the pre‐ and immediate post‐training surveys, 22 completed the delayed post‐training survey and 20 completed the JCS. The findings revealed increased confidence and comfort in public speaking post‐event, with sustained improvements over time, accompanied by positivity, pleasant feelings, and increased camaraderie. Post‐training delayed results also showed that reduced symptoms of anxiety before a speech were reported. The JCS highlighted that many participants had not properly acquired public speaking skills during university. Similarly, 19 out of 20 participants felt that leadership skills were important in contemporary dentistry but not properly taught in dental school curriculums.ConclusionsThe 2023 EAO SC was a successful event providing advanced training in leadership and public speaking skills. However, a notable number of young dentists continue to experience anxiety when faced with presentations, indicating a potential need for additional training to relieve stress and enhance confidence.
Material and abutment selection for CAD/CAM implant‐supported fixed dental prostheses in partially edentulous patients – A narrative review
Authors: Strasding Malin , Marchand Laurent , Merino Elizabeth , Zarauz Cristina , Pitta João 
Published: June 2024

AbstractRestorative material selection has become increasingly challenging due to the speed of new developments in the field of dental material science. The present narrative review gives an overview of the current indications for implant abutments and restoration materials for provisional and definitive implant‐supported fixed dental prostheses in partially edentulous patients. For single implant restorations, titanium base abutments for crowns are suggested as an alternative to the conventional stock‐ and customized abutments made out of metal or zirconia. They combine the mechanical stability of a metallic connection with the esthetic potential of ceramics. For multiple‐unit restorations, conical titanium bases especially designed for bridges are recommended, to compensate for deviating implant insertion axes and angulations. Even though titanium base abutments with different geometries and heights are available, certain clinical scenarios still benefit from customized titanium abutments. Indications for the definitive material in fixed implant restorations depend on the region of tooth replacement. In the posterior (not esthetically critical) zone, ceramics such as zirconia (3–5‐Ymol%) and lithium‐disilicate are recommended to be used in a monolithic fashion. In the anterior sector, ceramic restorations may be buccally micro‐veneered for an optimal esthetic appearance. Lithium‐disilicate is only recommended for single‐crowns, while zirconia (3–5‐Ymol%) is also recommended for multiple‐unit and cantilever restorations. Attention must be given to the specific mechanical properties of different types of zirconia, as some feature reduced mechanical strengths and are therefore not indicated for all regions and restoration span lengths. Metal‐ceramics remain an option, especially for cantilever restorations.
Sustainable scouring of cotton using extracts from wood ash and soapnut and its optimisation by response surface methodology
Authors: Patil Harshal , Athalye Ashok 
Published: June 2024

AbstractThe non‐cellulosic impurities like oil, wax, and pectins present in the cotton fibre adversely impact wetting. Consequently, these impurities must be removed during the pretreatment process to prevent unevenness of subsequent coloration. Generally, an alkaline treatment with petroleum‐based synthetic surfactants is done, which is called scouring. This study attempts to develop an environmentally safe alternative using alkali from wood ash extract (WAE) and surfactant from soapnut extract (SE). The factors of WAE (10%–30%), SE (5–15 g/L), temperature (75–95°C), and time (20–60 min) were optimised using response surface methodology. A concentration of 20% WAE and 10 g/L SE at 90°C for 30 min was found to be adequate to remove impurities. The statistically optimised method showed good hydrophilicity, indicated by an average wetting time of 15 s, and 2.7% weight loss. The scoured fabric was subsequently dyed with natural dye extracted from marigold flowers and reactive dye. The scoured cotton was evaluated by weight loss, wettability, tensile strength, whiteness index, and colour value (K/S) and showed comparable results to conventional scouring.
The indirect impact of infant negative emotionality on interparental conflict via perceptions of coparenting challenges: What prenatal resources mitigate this risk?
Authors: Calkins Frances C. , Finkelstein Seth D. , Martin Meredith J. , Brock Rebecca L. 
Published: June 2024

AbstractResearch clearly demonstrates that conflictual interparental relationship dynamics can create a family context that contributes to child emotional insecurity and psychopathology. Significantly less research has examined familial factors that contribute to maladaptive conflict between parents. Scholars have alluded to the disruptive impacts of parenting a child with certain temperamental characteristics (e.g., negative emotionality). Yet, there is a lack of empirical research examining if and how child temperament contributes to later interparental conflict. Using an established multi‐informant, multi‐method sample of 150 families first assessed during pregnancy, and again when the child was 1, 2, and 3.5 years of age, the present study aimed to test an integrated conceptual model examining whether infants' negative emotionality assessed at age 1 predicts interparental conflict at age 3.5, as mediated through destructive coparenting dynamics in toddlerhood, and identifying prenatal protective factors mitigating this maladaptive pathway. Findings suggest that greater infant negative emotionality predicts worse interparental conflict management during preschool age by undermining the mother's (but not the father's) report of coparenting relationship quality during toddlerhood. However, these results were significant only to the extent that parents were lacking certain prenatal regulatory resources (i.e., low paternal self‐compassion; less secure relationship between parents). Importantly, results point to the need for intervention and prevention efforts during pregnancy that might disrupt the deleterious impacts of parenting a child who is more reactive and prone to expressing negative emotions.
Impacts of hydrologic management on the eutrophication of shallow lakes in an intensive agricultural landscape (Saskatchewan, Canada)
Authors: Gushulak Cale A. C. , Chegoonian Amir M. , Wolfe Jared , Gray Kristen , Mezzini Stefano , Wissel Bjoern , Hann Brenda , Baulch Helen M. , Finlay Kerri , Leavitt Peter R. 
Published: June 2024

Abstract

Hydrologic management of shallow lakes is often undertaken to prevent fluctuations in lake level, and to ensure sufficient water volume for economic, domestic, and recreational uses, but there is inconsistent evidence of whether lake‐level stabilisation through hydrological management promotes or hinders eutrophication.

Here we used multi‐proxy paleolimnological assessments of water quality (sedimentary carbon, nitrogen, total phosphorus, fossil pigments), and zooplankton community ecology (fossil Cladocera assemblages), combined with Landsat‐derived estimates of lake surface area in two shallow eutrophic lakes, in the Prairies of southern Saskatchewan, Canada, to quantify how 8 decades of contrasting hydrological management strategies (continuous or intermittent) affect primary production and phytoplankton composition.

Analysis revealed that irregular hydrological management of Pelican Lake led to sharp increases in primary production concomitant with lake‐level decline. In contrast, continuously managed Buffalo Pound Lake, a drinking water reservoir for regional cities, exhibited slow, persistent eutrophication over decades despite active regulation of water levels. In both lakes, strong correlations of δ 15N values with pigments from diazotrophic cyanobacteria (canthaxanthin) showed that N2‐fixation increased during eutrophication irrespective of the timing of change. Finally, variation in fossil cladoceran density and composition reflected changes in pelagic and littoral habitats (e.g., reduced macrophyte cover) due to changes in both lake level and water quality.

Basin comparison shows that while hydrologic management can moderate water quality degradation due to lake‐level change, it does not prevent eutrophication when nutrient influx remains high.

Given that regional water availability is forecast to decline in coming decades, we anticipate that continued hydrological management will be unavoidable and will be unable to improve water quality unless nutrient influx is also controlled.
Unveiling the gaps: Hypertension control beyond the cascade of care framework
Authors: Silberzan Léna , Bajos Nathalie , Kelly‐Irving Michelle 
Published: June 2024

AbstractThis study examines hypertension control beyond the cascade of care framework, which assesses awareness, treatment, and control sequentially. The analysis included 52 434 hypertensive adults (blood pressure (BP) ≥140/90 mm Hg and/or treatment in the past 6 months), aged 25–69, from the French population‐based CONSTANCES cohort from 2012 to 2021. The authors assessed the typical “awareness, treatment, and control” scenario and characterized other possible control patterns. The authors found that 13% achieved control. This percentage rose to 19% when considering individuals who were not aware but treated and controlled. This alternative control scenario was associated with female sex, younger age, higher education, Northern‐African origin, and reporting prior cardiovascular diseases (CVD). Sub‐Saharan African origin, diabetes and overweight/obesity were associated with the typical control scenario. This study highlights that applying a typical sequential cascade of care approach may lead to the exclusion of some specific groups of participants who do not fit into the defined categories.
The vulnerability of sharks, skates, and rays to ocean deoxygenation: Physiological mechanisms, behavioral responses, and ecological impacts
Authors: Waller Matt J. , Humphries Nicolas E. , Womersley Freya C. , Loveridge Alexandra , Jeffries Amy L. , Watanabe Yuuki , Payne Nicholas , Semmens Jayson , Queiroz Nuno , Southall Emily J. , Sims David W. 
Published: June 2024

AbstractLevels of dissolved oxygen in open ocean and coastal waters are decreasing (ocean deoxygenation), with poorly understood effects on marine megafauna. All of the more than 1000 species of elasmobranchs (sharks, skates, and rays) are obligate water breathers, with a variety of life‐history strategies and oxygen requirements. This review demonstrates that although many elasmobranchs typically avoid hypoxic water, they also appear capable of withstanding mild to moderate hypoxia with changes in activity, ventilatory responses, alterations to circulatory and hematological parameters, and morphological alterations to gill structures. However, such strategies may be insufficient to withstand severe, progressive, or prolonged hypoxia or anoxia where anaerobic metabolic pathways may be used for limited periods. As water temperatures increase with climate warming, ectothermic elasmobranchs will exhibit elevated metabolic rates and are likely to be less able to tolerate the effects of even mild hypoxia associated with deoxygenation. As a result, sustained hypoxic conditions in warmer coastal or surface‐pelagic waters are likely to lead to shifts in elasmobranch distributions. Mass mortalities of elasmobranchs linked directly to deoxygenation have only rarely been observed but are likely underreported. One key concern is how reductions in habitat volume as a result of expanding hypoxia resulting from deoxygenation will influence interactions between elasmobranchs and industrial fisheries. Catch per unit of effort of threatened pelagic sharks by longline fisheries, for instance, has been shown to be higher above oxygen minimum zones compared to adjacent, normoxic regions, and attributed to vertical habitat compression of sharks overlapping with increased fishing effort. How a compound stressor such as marine heatwaves alters vulnerability to deoxygenation remains an open question. With over a third of elasmobranch species listed as endangered, a priority for conservation and management now lies in understanding and mitigating ocean deoxygenation effects in addition to population declines already occurring from overfishing.
Establishment of an in vitro cell coculture model for investigating the whitening mechanism of Paeonia lactiflora Pall seeds oil
Authors: Chen Zhixiong , Cao Ping , Zhang Yicheng , Hong Ni , Li Ping , Yao Hong 
Published: June 2024

AbstractBackgroundIn vitro single‐cell experiments may yield inconsistent results compared to clinical trials. To enhance the reliability of cosmetic active ingredient screening, a coculture model of B16F10‐HaCaT cells was established in vitro based on the structural characteristics of human skin, thereby improving the credibility of experimental outcomes. Currently, most cosmetic whitening additives primarily target simple efficacy goals such as inhibiting tyrosinase activity or melanin transfer. Therefore, investigating novel and efficient whitening additives has become a prominent research focus.ObjectivesThe aim is to establish an in vitro cell coculture model for more reliable experimental results and investigate the mechanism by which Paeonia lactiflora Pall seeds oil inhibits melanin production and transfer.MethodsThe impact of different concentrations of Paeonia lactiflora Pall seeds oil on cocultured cell proliferation rate was assessed using cck8 assay. Tyrosinase inhibition ability in cocultured cells was tested using levodopa as a substrate. Melanin production inhibition ability in coculture cells was evaluated by lysing cells with sodium hydroxide. The effect of Paeonia lactiflora Pall seeds oil on dendrite‐related gene expression levels was examined through qPCR analysis. Additionally, Western blotting was employed to study the effect of Paeonia lactiflora Pall seeds oil on dendrite‐related protein expression levels.ResultsDifferent concentrations of Paeonia lactiflora Pall seeds oil did not affect the proliferation activity of cocultured cells. A specific concentration of α‐MSH increased cell tyrosinase activity, cellular melanin content, as well as Rac1, Cdc42, and PAR‐2 gene and protein expression related to dendritic formation. Treatment with a certain concentration of Paeonia lactiflora Pall seeds oil resulted in decreased tyrosinase activity and melanin content in cells along with downregulated expression levels of Rac1, Cdc42, and PAR‐2 genes and proteins associated with dendritic formation.ConclusionsPaeonia lactiflora Pall seeds oil at specific concentrations exhibits the ability to inhibit tyrosinase activity, decrease melanin content, and possesses the potential to impede melanin transfer.
Viral complexity of tomatoes yellow mosaic and leaf curl diseases in lowland and highland areas
Authors: Hermanto Rudy , Murti Rudi Hari , Hartono Sedyo , Purwantoro Azis , Wijonarko Arman , Mulyantoro  , Nahampun Hartinio Natalia , Afifuddin Ahmad 
Published: June 2024

AbstractYellow mosaic and leaf curl diseases caused by whitefly‐transmitted begomo virus genera are important problems in tomato (Solanum lycopersicon L.) production in Indonesia, particularly on Java Island. The aims of this survey are to assess the percentages of disease incidence (DI) and disease severity index (DSI), evaluate the spread and complexity of begomovirus and crinivirus infections responsible for yellow mosaic and leaf curl diseases in tomato plants, and identify the species of whitefly insect vectors and their cryptic biotypes in tomato production centers located on Java Island, Indonesia. A total of 43 locations in East, Central, and West Java were surveyed during the dry season from July 2022 to September 2022. Disease incidence and severity were determined by observing 200 samples of tomato plants from five points at each location, with 40 plants per point of land. A total of 116 whitefly samples in microtubes and 215 symptomatic leaf samples were collected. The genus begomovirus and crinivirus infecting tomato were identified by PCR and RT‐PCR using genus‐specific primers. Similarly, whitefly species and their cryptic biotypes were identified by PCR using MCoI gene‐specific primers. Results showed that DI and DSI remarkably differed between the lowlands (66%–89%) and highlands (33%–62%) in the provinces of Central Java and West Java. Furthermore, PCR analysis of 215 infected tomato showing the symptoms of yellow mosaic and curly leaf revealed that three begomoviruses, one crinivirus and their mixed combination both begomoviruses, one crinivirus has been detected in all the samples. Similarly, the whitefly insect vector Bemisia tabaci biotype Q was identified in all areas, whereas Trialeurodes vaporariorum was found only in the East Java and Java highlands, respectively.
The effect of dietary administration of Saussurea lappa root on performance, blood biochemical indices, redox status, innate immune response, intestinal microbial population and resistance against A. hydrophila infections of Tilapia Fingerlings
Authors: Naiel Mohammed A. E. , Abd El‐hameed Samah A. A. , Ahmed Amany I. , Ismaiel Nahla E. M. 
Published: June 2024

AbstractThis experiment was performed to identify the influence of dietary Saussurea lappa root (SLR) on the performance and general health status of Nile Tilapia fingerlings (O. niloticus). Four formulated diets with different SLR levels of 0.0, 2.5, 5 and 10 g/kg, respectively, were afforded to fingerling fish (15.42 ± 0.05 g) for 8 weeks. The feed efficiency ratio (FER), feed intake (FI) and feed conversion ratio varied with dietary SLR level in a linear model and a high feed efficiency rate was recorded at the 10 g/kg group, while FI and FCR exhibited an opposite trend (P < 0.001). Dietary SLR level influenced serum protein constituents, liver and renal function enzymes, triglycerides, cholesterol and glucose (P < 0.001). Serum Catalase (CAT), total antioxidant capacity (T‐AOC) and superoxide dismutase (SOD) remarkedly increased with dietary SLR level and attained a level at 10 g/kg. Furthermore, serum lysozyme, complement C3 (C3), IgA and IgD were stimulated by 10 g/kg SLR. Intestinal digestive enzymes (lipase and amylase) increased with SLR level up to 10 g/kg. As the dietary SLR level raised, the cumulative survival percentage aginst A. hydrophila challenge increased and then reached a maximum at 10 g/kg SLR group. Moreover, gene expression of pro‐inflammation cytokines (TNF‐2a, IL‐1β, and IL‐10) in liver and kidney transcriptomes demonstrated effective immunostimulant capabilities of greater SLR inclusion levels in fish diet. Meanwhile, intestinal microbial investigation, revealed that high levels of SLR in tilapia fish feed significantly suppressed total bacterial count, and pathogenic bacterial count (such as, E. coli, Coliform, Aeromonas spp, Pseudomonas spp.), and stimulated lactic acid bacteria development. Finally, it is recommended to include a high level of SLR (5 or 10 g/kg) in the diet of O. niloticus fingerlings to enhance feed efficiency, antioxidant characteristics, and immunological response against bacterial infections.