bluuebunny/crossref_metadata_2025_split huggingface dataset:
Judicial Corruption dan Analisis Tindak Pidana Korupsi Bantuan Dana Likuiditas Bank Indonesia Berdasarkan Teori Sebab-sebab Tindak Pidana Korupsi: Studi Kasus Syafruddin Arsyad Temenggung
Authors: Muliana  
Published: April 2024

Abstack
Bantuan Likuiditas Bank Indonesia (BLBI) was born out of a situation at that time when an economic crisis hit Indonesia, where the rupiah exchange rate against the dollar fell very sharply, decreased exports and imports, collapsed banking, sluggish real sector and increased unemployment . Thus, on September 3, 1997, the President instructed the Minister of Finance and the Governor of Bank Indonesia to assist national banks which were sick and lacking liquidity. In addition, it provides the option to be merged with healthy banks or if it is successful too, the main focus is to protect depositors. Of the several suspects in the BLBI corruption case, this journal discussion will focus more on the BLBI corruption crime committed by the defendant Syafruddin Arsyad Tumenggung as the Former Chairman of the Indonesian Bank Restructuring Agency (IBRA) or the owner of PT. Fortius Investment Asia by analyzing the verdict that has been handed down against Syafruddin at the district court until the cassation.

Abstrak
Bantuan Likuiditas Bank Indonesia (BLBI) lahir dari situasi yang pada saat itu sedang terjadi krisis ekonomi melanda Indonesia, di mana nilai tukar rupiah terhadap dolar merosot dan lemah dengan sangat tajam, turunnya ekspor dan impor, perbankan yang kolaps, lesunya sektor riil dan bertambahnya pengangguran. Sehingga, pada 3 September 1997, Presiden menginstruksikan Menteri Keuangan dan Gubernur Bank Indonesia untuk membantu bank nasional yang sakit dan likuiditasnya kurang. Selain itu, memberikan opsi untuk digabung dengan bank-bank yang sehat atau jika berhasil juga, maka fokus utama adalah melindungi deposan. Dari beberapa tersangka dalam kasus tindak pidana korupsi BLBI, dalam pembahasan jurnal kali ini akan lebih difokuskan terhadap tindak pidana korupsi BLBI yang dilakukan oleh terdakwa Syafruddin Arsyad Tumenggung selaku Mantan Ketua Badan Penyehatan Perbankan Nasional (BPPN) atau Pemilik PT. Fortius Investment Asia dengan menganalisis putusan yang telah dijatuhkan terhadap Syafruddin pada Pengadilan negeri hingga kasasi.
Pertanggungjawaban Pidana Promosi Saham Yang Menyebabkan Terjadinya Manipulasi Pasar Dengan Melibatkan Public Figure
Authors: Marina Adelia Putri 
Published: April 2024

Abstract
This research is entitled "Criminal Liability for Promotion of Stocks Causing Market Manipulation by Involving Public Figures". The formulation of the problems proposed 1) Criminal liability for stock promotion that causes market manipulation by companies involving Public Figures, and 2) Legal protection for investors who are harmed due to stock promotion actions that result in market manipulation. In connection with the phenomenon of stock promotion actions, it is deemed necessary to study in which case this stock promotion leads to a criminal act of market manipulation as referred to in the Capital Market Law, so that the perpetrators can be charged with the provisions of Article 91 and their criminal sanctions. In addition, the application of criminal sanctions is not sufficient to accommodate the interests of the victims, in this case the investors who are harmed. As an effort to recover investors' losses from stock promotion actions that result in market manipulation, investors can submit applications for restitution and illegal returns of profits and compensation funds.

Abstrak
Penelitian ini berjudul “Pertanggungjawaban Pidana Promosi Saham yang Menyebabkan Manipulasi Pasar dengan Melibatkan Public Figure”. Rumusan masalah yang diajukan 1) Pertanggungjawaban pidana promosi saham yang menyebabkan terjadinya manipulasi pasar oleh perusahaan yang melibatkan Public Figure, dan 2) Perlindungan hukum bagi investor yang dirugikan akibat tindakan promosi saham yang berakibat terjadinya manipulasi pasar. Berkaitan dengan fenomena tindakan promosi saham dirasa perlu untuk dikaji dalam hal mana promosi saham ini mengarah pada tindak pidana manipulasi pasar sebagaimana dimaksud dalam Undang-Undang Pasar Modal, sehingga para pelakunya dapat dijerat ketentuan Pasal 91 beserta sanksi pidananya. Selain itu, penerapan sanksi pidananya tidak cukup untuk mengakomodir kepentingan korban dalam hal ini investor yang dirugikan. Sebagai upaya untuk pengembalian kerugian investor atas tindakan promosi saham yang berakibat terjadinya manipulasi pasar maka pengajuan permohonan restitusi dan pengembalian keuntungan secara tidak sah dan dana kompensasi dapat dilakukan investor.
Penggunaan Material Mycelium dalam Perancangan Kembali Microlibrary Warak Kayu
Authors: Fonna Farhah Amira , Irsyad Diva Iryanti , Adriansyah Kaylila Fathia , Qonitah Labitta , Koerniawan Mochamad Donny 
Published: April 2024

<p><em>Mycelium composites are emerging as a new sustainable. Mycelium is a fungi that is produced from the remains organisms and can be used as a natural adhesive to unite and grow in a biomass.</em> <em>By responding to a critical evaluation of SHAU Indonesia's Warak Kayu Microlibrary, this paper aims to explore and develop bio-design in the use of mycelium as a sustainable alternative to architectural elements. In this paper, agricultural waste such as coffee grounds and wood will be used as substrates in the formation of mycelium composites. . The method used in this research is descriptive qualitative methods with data collection derived from literature studies and followed by data analysis. From this paper, it is found that mycelium can be used as an architectural element in the form of facade panels that pay attention to audial comfort by utilizing agricultural waste as nutrients for mycelium to be processed into a material.</em></p>
Pendampingan Pembuatan Media Tanam Budidaya Tanaman Anggur sebagai Konsep Urban Farming
Authors: Putra Heristama , Kristianto Ryan , Andrian David , Hutabarat Daniel Gentario , Kristin Elisabeth Yolanda 
Published: April 2024

The population of the city of Surabaya currently reaches approximately three million people, which makes the density level increase from year to year. The need for residential housing is the main factor in reducing open land in the city of Surabaya. Most of the land that becomes residential or housing is managed by housing developers (developers) who continue to clear land for the development process to cater to urbanites. Urban farming activities can increase residents' enthusiasm for farming in urban environments and for food needs, in this case the cultivation of horticultural crops. The problem that the residents want to solve is cultivating grapes, so media will also be created in the form of facilities and infrastructure so that grape cultivation can grow and develop well until it produces fruit in good condition. The implementation method used is the verticulture method. In this method, activity stages are carried out starting from preparation, socialization, training, mentoring and evaluation. So that the results of cultivating grapes can be sold by residents as additional cash for the RT. Apart from that, residents can also use it themselves for consumption together. The main point of the activity is that residents can learn how to plant from seeding to fertilization of grapes, considering the nature of grapes which grow by vines.

Abstrak
Penduduk kota Surabaya saat ini mencapai kurang lebih tiga juta jiwa yang membuat tingkat kepadatan dari tahun ke tahun semakin meningkat. Kebutuhan akan hunian tempat tinggal menjadi faktor utama berkurangnya lahan terbuka di kota Surabaya. Sebagian besar lahan yang menjadi pemukiman ataupun perumahan dikelola oleh pengembang perumahan (developer) yang terus melakukan pembukaan lahan untuk proses pembangunan guna memenuhi para kaum urban. Kegiatan urban farming dapat meningkatkan semangat warga dalam hal bercocok tanam di lingkungan perkotaan dan akan kebutuhan pangan dalam hal ini adalah budidaya tanaman hortikultura. Masalah yang ingin diselesaikan bersama warga yakni melakukan budidaya tanaman anggur, maka akan dibuatkan juga media berupa sarana dan prasarana agar tanaman budidaya anggur ini dapat tumbuh dan berkembang dengan baik hingga menghasilkan buah dengan kondisi yang baik pula. Metode pelaksanaan yang digunakan yakni metode vertikultur. Pada metode ini dilaksanakan tahap kegiatan mulai dari persiapan, sosialisasi, pelatihan, pendampingan dan evaluasi. Sehingga dari hasil budidaya tanaman anggur tersebut dapat dijual oleh warga sebagai tambahan uang kas bagi RT. Selain itu juga dapat dimanfaatkan sendiri oleh warga untuk dikonsumsi bersama. Pokok utama kegiatan yaitu warga dapat belajar cara menanam sejak mulai dari pembibitan hingga pembuahan dari tanaman anggur, mengingat sifat tanaman anggur yang tumbuh secara merambat.
Digital images generated by Artificial Intelligence as ethnographic experimentation
Authors: Helanski Cardoso Juliane Cristina 
Published: April 2024

The article discusses the role of images produced by artificial intelligence (AI) in visual anthropology, highlighting their ability to represent identity and experience. It also addresses the technical and ethical challenges of AI data classification and its interaction with socio-technical networks, questioning technological neutrality. Technical implications include data categorization that can perpetuate biases and power relations. The simplification and distortion of representations by AI is highlighted, requiring a critical analysis of the stories embedded in the categorizations. It is proposed that anthropologists examine the relationship between image, label, and referent, recognizing differences and similarities in their roles and those of AI labelers in knowledge production. In addition, it discusses how AI images can influence anthropological interpretation and analysis by blending reality and emotion. It is argued that a critical engagement with the ethical and technical implications of the generation and use of these images is necessary.
Polyacrylic acid-polyvinylpyrrolidone complex for achieving hemostasis after hemodialysis: study protocol for an open-label crossover randomized controlled trial (PAA-PVP study)
Authors: Terashima Ryohei , Tanaka Mototsugu , Hashimoto Atsushi , Omori Daiki , Tanaka Takahiro , Miyazawa Haruna , Ishizawa Masahiro , Tomita Yoshihiko , Ito Tomoko , Koyama Yoshiyuki , Saito Kokichi , Yamamoto Suguru , Goto Shin , Narita Ichiei 
Published: April 2024

Abstract

Background
Achieving rapid and secure hemostasis of the vascular access point is important for patients undergoing maintenance hemodialysis (HD). We developed a polyacrylic acid-polyvinylpyrrolidone (PAA-PVP) complex that absorbs moisture such as blood or sterilizing solution, forms a hydrogel, and adheres to the body’s surface, thereby exerting a powerful hemostatic effect. This study aims to compare the effect of PAA-PVP complex versus a conventional non-woven fabric pad on hemostasis at the needle puncture vascular access site in patients on HD.
Methods
This open-label crossover randomized controlled trial will include 50 participants who undergo thrice-weekly HD. Participants in whom hemostasis requires more than 10 min by compression using a conventional pad or who have a severe skin problem at the needle puncture vascular access site will be excluded from the study. Participants will be randomized in a 1:1 ratio to receive either the PAA-PVP complex or conventional pads. Three consecutive weekly hemostatic tests will be performed at 11, 9, 7, 5, 3, and 1 min. The study will employ an individual 3 + 3 design in which participants in whom hemostasis is achieved in all three sessions in a week will be challenged to a shorter time in the three sessions of the next week. Those in whom hemostasis is achieved in two of three sessions will be tested at the same time point in the three sessions of the next week. The study treatment will be terminated if hemostasis is achieved in only one or none of the sessions, and the minimum time with three consecutive successes will be recorded as the hemostasis time. The primary endpoint, the hemostasis time on the arterial side of the vascular access, will be analyzed using mixed-effect models for repeated measures and include the hemostatic technique and group, period, and individual effects as covariates.
Discussion
The study will provide evidence on whether the PAA-PVP complex reduces hemostasis time of the vascular access compared to conventional pad in patients on HD.
Trial registration
jRCTs032220597 (Japan Registry of Clinical Trials; registered on January 30, 2023, https://jrct.niph.go.jp/latest-detail/jRCTs032220597)
Assessing the Impact of Modified Intermittent Fasting and Daily Calorie Restriction on Appetite, Food Cravings, and Eating Habits of Overweight and Obese Women Aged 18 to 50 Years: Protocol for a Randomized Controlled Trial
Authors: Esmaili Helia , Hooshiar Saeedeh Hosseini , Yazdani Akram , Jafarnejad Sadegh 
Published: April 2024

Abstract

Background
An imbalance in appetite and eating behavior, accompanied by heightened food cravings, disrupts the equilibrium between energy intake and energy expenditure, leading to the development of obesity and overweight conditions. There are different dietary strategies to control obesity complications, yet their effects on food behaviors remain an understudied aspect of these interventions. One such intervention gaining increasing attention is intermittent fasting, particularly modified intermittent fasting.
Methods
This research constitutes a randomized controlled parallel-group trial aimed at comparing the impact of a modified intermittent fasting diet and a daily calorie restriction diet on various factors including appetite, food cravings, eating behavior, and anthropometric indices in women who are classified as either overweight or obese. The study will span a duration of 8 weeks. A total of fifty-four eligible participants will be carefully matched based on their age and BMI, and subsequently allocated to either the "modified intermittent fasting" group or the "daily calorie restriction" group. The primary outcomes include the Visual Analog Scales (VAS) for appetite, the Food Craving Questionnaire (FCQ), the Dutch Eating Behavior Questionnaire (DEBQ), BMI, and Fat-Free Mass (FFM). As secondary outcomes, the study will also explore changes in waist circumference and body fat mass.
Discussion
This study investigates the effects of an 8-week intermittent fasting intervention compared to a daily calorie restriction approach on appetite, food cravings, and eating behavior. By obtaining this information, we seek to enhance our understanding of the intermittent fasting diet and its potential effects in these domains.
Trial registration:
Iranian Registry of Clinical Trials IRCT20220522054958N2. Registered on 30 May 2022. https://irct.behdasht.gov.ir/trial/63737.
Prognostic factors associated with acute retinal necrosis treated non-surgically
Authors: Liu Xiaoli , Wei Haihui , Xu Wenjing , Jiang Hai , Jin Siyan 
Published: April 2024

Abstract

Objectives
To analyze the prognostic factors for visual acuity in acute retinal necrosis syndrome (ARN) patients treated non-surgically.
Methods
The clinical data of ARN patients who visited our hospital from January 2010 to January 2023 were retrospectively analyzed.
Results
Twenty-four patients (29 eyes) were included. Aqueous humor samples were collected from 20 out of 29 eyes, and PCR confirmed that 85% (17/20) of the eyes had VZV infection, 10% (2/20) had CMV infection, and 5% (1/20) had HSV infection. All patients were treated with intravenous antiviral agents. Intravitreal ganciclovir and oral corticosteroids were given according to the patients’ wishes. A comparison of visual acuity at the last follow-up with that at the first visit revealed that 16 (55.2%) eyes improved and 13 (44.8%) did not improve. Logistic regression analysis revealed that risk factors for failure to improve vision after treatment included retinal detachment, necrotizing retinitis involving the posterior pole, and arteritis involving the large retinal arteries. The VZV viral load in the aqueous humor at initial presentation was significantly associated with visual prognosis (P = 0.013), retinal detachment (P = 0.019) and the extent of retinal necrosis(P = 0.03). The NLR of VZV-infected patients at first presentation was significantly correlated with the prognosis of visual acuity (P = 0.033) and retinal detachment (P = 0.003).
Conclusions
At initial presentation, a high NLR and high viral DNA copy number in the aqueous humor were risk factors for poor visual acuity in VZV-infected ARN patients.
Patient-reported Therapeutic Benefits of Herbal Medicines in the Treatment of Gynecological Ailments
Authors: Drebka Alexandra , Scholl Annika J. , Ochs Teresa , Kelber Olaf , Mösges Ralph , Raskopf Esther , Shah-Hosseini Kija , Bachmeier Beatrice E. 
Published: April 2024

Abstract

Background: Gynaecological ailments have a negative impact on quality of life and productivity. Standard treatment is associated with poor tolerability and other issues related to public health and environment. Herbal Medicines (HMs) are used traditionally for the treatment of menstrual and menopausal ailments as well as uncomplicated urinary tract infections for centuries and constitute an excellent addition to current treatment options. HMs are well tolerated, non-polluting and therapeutically efficacious as evidenced by various clinical studies. Aim of this study was to expand the evidence regarding therapeutic efficacy of HMs for the treatment of gynaecological complaints by complementing knowledge from clinical studies with real world evidence from patient reported outcomes.
Methods: We applied descriptive statistical methods and analyzed a data sample taken from the pharmaco-epidemiological database PhytoVIS regarding frequency and percentage.
Thereafter we evaluated the therapeutic benefit of herbal medicines (HMs) in gynaecological complaints as well as side effects.
Results: More than 80% of the patients in the sample assessed the overall therapeutic benefit of HMs for the treatment of gynaecological complaints as very positive. Over 90% of the patients using HMs perceived no or no significant side effects. Treatment habits differed depending on the type of complaint. In this context the majority of women with menstrual or menopausal ailments preferred to treat for time period of 1 month or longer, while those affected by uncomplicated urinary tract infections reduced the application of HMs to the length of their symptoms. Interestingly women with even strong symptoms relied on the therapeutic benefit of HMs.
Conclusion: Real-world outcome data are an important supplement to clinical data. Our results reveal the excellent benefit-risk ratio of HMs and help to implement them into novel therapeutic strategies to treat gynaecological complaints.
Circadian control of a sex-specific behaviour in Drosophila
Authors: Franco Diana , Riva Sabrina , Ceriani Maria , Risau-Gusman Sebastián 
Published: April 2024

Abstract

An endogenous circadian clock controls many of the behavioral traits of Drosophila melanogaster. This ¨clock¨ relies on the activity of interconnected clusters of neurons that harbor the clock machinery. The hierarchy among clusters involved in the control of rest-activity cycles has been extensively studied. Sexually dimorphic behaviors, on the other hand, have received less attention. Even though egg-laying, a female characteristic behavior, has been shown to be rhythmic, it remains largely unexplored possibly due to metholodological constraints. The current study provides the first steps towards determining the neural substrates underlying the circadian control of egg-laying. We show that, whereas the lateral ventral neurons (LNvs) and the dorsal neurons (DNs) are dispensable, the lateral dorsal neurons (LNds) are necessary for rhythmic egg-laying. Systematically probing the Drosophila connectome for contacts between circadian clusters and oviposition-related neurons, we found no evidence of direct connections between LNvs or DNs and neurons recruited during oviposition. Conversely, we did find bidirectional connections between Cryptochrome (Cry) expressing LNd (Cry+ LNds) and oviposition related neurons. Taken together, these results reveal that cry positive LNd neurons have a leading role in the control of the egg-laying rhythm in Drosophila females.
Molecular and Functional Profiling of Gαi as an Intracellular pH Sensor
Authors: Campbell Sharon , Prakash Ajit , Li Zijian , Chirasani Venkat , Rasquinha Juhi , Valentin Natalie , Hubbard Garrett , Yin Guowei , Dohlman Henrik 
Published: April 2024

Abstract

Heterotrimeric G proteins (Gα, Gβ and Gγ) act downstream of G-protein-coupled receptors (GPCRs) to mediate signaling pathways that regulate various physiological processes and human disease conditions. Previously, human Gαi and its yeast homolog Gpa1 have been reported to function as intracellular pH sensors, yet the pH sensing capabilities of Gαi and the underlying mechanism remain to be established. Herein, we identify a pH sensing network within Gαi, and evaluate the consequences of pH modulation on the structure and stability of the G-protein. We find that changes over the physiological pH range significantly alter the structure and stability of Gαi-GDP, with the protein undergoing a disorder-to-order transition as the pH is raised from 6.8 to 7.5. Further, we find that modulation of intracellular pH in HEK293 cells regulates Gαi-Gβγ release. Identification of key residues in the pH-sensing network allowed the generation of low pH mimetics that attenuate Gαi-Gβγ release. Our findings, taken together, indicate that pH-dependent structural changes in Gαi alter the agonist-mediated Gβγ dissociation necessary for proper signaling.
Modi-2, a vaccine stimulating CD4 mediated responses to homocitrullinated self-epitopes, as a therapy for solid cancers
Authors: Durrant Lindy , Al-Omari Abdullah , Cook Katherine , Symonds Peter , Skinner Anne , Zhu Yaling , Coble Vincent , Mohammed Omar , Choudhury Ruhul , Uddin Nazim , Ranglani Priscilla , Parry Adrian , Adams Sally , Lynn Geoffrey , Brentville Victoria 
Published: April 2024

Abstract

Stresses within the tumour microenvironment can mediate post-translational modifications (PTM) of self-proteins. Homocitrullination is the conversion of lysine residues to homocitrulline which can generate neoepitopes and bypass self-tolerance. In this study a vaccine targeting homocitrullinated peptide antigens was assessed for its ability to stimulate anti-tumour immunity. Peptides that bind HLA are often hydrophobic which can lead to complications with large scale manufacture and solubility that must be considered in the design of vaccines. Here we demonstrate the use of a self-assembling nanoparticle technology (SNAPvaxTM) to co-deliver four homocitrullinated peptides and adjuvant in nanoparticles of a precise size and composition as a vaccine (“Modi-2”) that is optimized for manufacturing ease and T cell induction. The vaccine stimulated strong Th1 cell responses and anti-tumour immunity in mouse tumour models with 40% overall survival against B16 melanoma (p=0.0113), 100% survival against CT26 colorectal cancer (p<0.0001) and 70% survival against 4T1 breast cancer (p=0.0090). We demonstrate that human lung, colorectal, breast and prostate tumours express the antigens that are targets of the Modi-2 vaccine. We therefore propose the Modi-2 vaccine utilizing homocitrullinated peptides and SNAPvax has potential for translation into clinic in several cancer indications.