bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dramatically elevated plasma vascular endothelial growth factor levels from influenza A infection in polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome: A case report
Authors: Kannan Ashwin , Zhuo Ying , Banerjee Rahul 
Published: June 2024

AbstractWe present a patient with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome who had a dramatic and sustained elevation in plasma vascular endothelial growth factor (VEGF) levels from 182 to 740 pg/mL while on lenalidomide‐dexamethasone therapy. Given his biochemical evidence of progression, second‐line daratumumab was added. In hindsight, a concurrent influenza A infection was the likely driver of his VEGF elevation rather than his underlying POEMS syndrome. Given the importance of longitudinal VEGF monitoring and the infectious risks of plasma cell therapies, our case highlights the need for caution with POEMS response assessments in the setting of a respiratory viral infection.
The promotion and implementation of open science measures among high‐performing journals from Brazil, Mexico, Portugal, and Spain
Authors: Fradkin Chris , Mugnaini Rogério 
Published: June 2024

AbstractThis study empirically examined the promotion and implementation of open science measures among high‐performing journals of Brazil, Mexico, Portugal, and Spain. Journal policy related to data sharing, materials sharing, preregistration, open peer review, and consideration of preprints and replication studies was gathered from the websites of the journals. Four hundred articles were coded for the inclusion of data availability statements, conflict of interest disclosures, funding disclosures, DOI, ORCID, and continuous publishing. Analyses found a higher promotion of open science measures among Brazilian journals than their Portuguese counterparts, and higher promotion of open science measures among international journals than their domestic counterparts. Analyses found higher implementation of open science measures among Brazilian journals than their Portuguese and Mexican counterparts. One journal out of 40 encouraged preregistration of studies; none encouraged replication studies and none had implemented open peer review. These findings reveal reasonably strong implementation of secondary open science measures (e.g., DOI, ORCID, conflict of interest and funding source disclosure) among the sample, but weaker implementation of primary measures (e.g., open data, open materials, replication studies and open peer review). The implications of these findings are considered and suggestions are made to bolster the adoption of open science measures among Ibero‐American scientific journals.
Study of slope stability analysis method based on equivalent Mohr‐Coulomb strength parameters of three‐dimensional stress state
Authors: Wu Shunchuan , Xia Lei , Han Longqiang , Chu Chaoqun , Zhang Min , Han Shun 
Published: June 2024

AbstractMost rock slope stability analysis methods are based on the Hoke–Brown criterion under a two‐dimensional state of stress, which somewhat ignores the effect of intermediate principal stress. In this paper, by introducing the improved three‐dimensional H‐B criterion into the Meridian plane, the tangent line of a point on the H‐B strength envelope is regarded as its instantaneous equivalent M‐C parameter. Based on this, a formula for solving the equivalent M‐C strength parameters under a three‐dimensional stress state is established to describe the shear strength parameters of rock mass, considering different stress states. Taking three kinds of rocks as examples, the influence of the intermediate principal stress on their strength parameters is analyzed. On this basis, the realization scheme of the nonlinear strength reduction method is established, the stability of the slope is studied, and an example verifies the feasibility of this method. This method fully considers the nonlinear characteristics of rock slope strength parameters under a three‐dimensional stress state and provides a solid basis for slope stability analysis.
Modified eco‐friendly and biodegradable chitosan‐based sustainable semiconducting thin films
Authors: Lokesh Kumar S. , Servesh Anushka , Sunitha V. R. , Prasad J. Raj , Tabassum Sumaiya , Ramaraj Sankar Ganesh , Kumar Niraj , Govindaraju Santhosh 
Published: June 2024

AbstractSemiconducting materials are pivotal in various fields, such as solar cells, LEDs, photovoltaic cells, etc. A nature‐friendly chitosan is a good film‐forming, water‐soluble polymer that is modified to a small band‐gap polymer for various optoelectronic applications. Choline chloride:ethylene glycol:glycerin (1:1:1) deep eutectic solvent (DES)‐modified activated carbon is incorporated into the chitosan matric and this composite is fabricated into thin films via spin coating methodology. The obtained films are subjected to multiple studies such as scanning electron microscopy (SEM), X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), impedance spectroscopy, and UV–vis spectroscopy to perceive the thin‐films microstructure, morphology, conductance, band gap, and optical nature. The integration of DES‐modified activated carbon has significantly improved the charge transfer capacity of chitosan by reducing the band gap from 4.0 to 2.0 eV. These notable characteristics exhibited by the modified films can be key to sustainable semiconducting materials and have the potential to transform several optoelectronic applications.
Innovation of advanced polymers from seafood waste: Applications of chitin and chitosan
Authors: Lalarukh  , Hussain Syed Makhdoom , Ali Shafaqat , Zahoor Ameer Fawad , Azmat Hamda , Nazish Nadia , Alshehri Mohammed Ali , Riaz Danish , Naeem Eman , Mahrukh  
Published: June 2024

AbstractDespite their importance to global economies, the aquaculture and seafood sectors are major contributors to waste, which is a problem for the environment. Because of its biocompatibility and recyclability, fish waste, which is rich in chitin and chitosan—holds potential in several fields. The shells of crustaceans are the source of chitin and chitosan, two substances with versatile and useful qualities. Although it is not very soluble, chitin is very biocompatible and biodegradable, much like cellulose. The more versatile and solubilized chitosan is made when chitin is deacetylated. About half of seafood waste is made up of cephalothoraxes and shrimp exoskeletons, and chitin is the second most common polysaccharide in the world. An eco‐friendly strategy for managing seafood waste and creating value may be found in investigating these compounds originating from the ocean. The byproduct of fish scales, chitosan, has many uses in the cosmetics, pharmaceutical, culinary, and aquaculture industries. Greener ways of chitin extraction include enzymatic deproteinization and microbial fermentations, as well as biological approaches like demineralization and deproteinization. Chitosan has several potential uses in biomedicine, food technology, and tissue engineering because of its acid solubility and precipitation at pH values greater than 6.0. It may be used in wound healing, water treatment, and agriculture due to its biocompatibility, biodegradability, and antibacterial qualities. Research on chitosan supplementation in several fish species suggests that it may improve immune responses. However, further research is needed to properly comprehend this. Oral chitosan use has the potential to lead to a more efficient and environmentally friendly aquaculture industry.
Particle filter‐based prognostics for composite curing process
Authors: Balaji Aravind , Dumas David , Pierard Olivier , Sbarufatti Claudio , Cadini Francesco 
Published: June 2024

AbstractProcess‐induced deformation (PID) arises in thermoset parts due to internal residual stress developed from their anisotropic properties, resulting in distortions. While passive numerical manufacturing control exists, active manufacturing control is crucial for enhancing the manufacturing process. The work focuses on diagnosing the polymerization reaction, known as the curing process, to consider the influence of uncertainties in thermal loading conditions on the behavior of cure kinetics. This is achieved using a Particle Filter approach, wherein a posterior distribution of cure evolution is recursively approximated based on observed measurements from characterization tests. The algorithm is designed to simultaneously perform the diagnosis and prognosis of the Degree of Cure and PID. This approach adopts the augmented cure formulation to address various scenarios with uncertainties in thermal loading conditions. It offers the advantage of providing comparable PID predictions with minimal computational costs. C‐shaped thermoset parts made of epoxy/carbon fibers with varying thicknesses are cured using the Manufacturing Recommended Curing Cycle, and the predictions with the developed algorithm are validated against experimental measures. Upon validation, the converged prognosis capability of the Particle Filter model is employed to assess the impact of thermal loading uncertainty on cure profiles, which, in turn, affects the final PIDs outcome.Highlights
A Bayesian sampling approach enables the estimation of cure kinetics parameters.
The estimated stochastic parameters forecast the process‐induced deformations.
The augmented Degree of Cure accounts for uncertainties linked to thermal loadings.
Analysis on AS4/8552 C‐shaped parts shows the cure kinetics impact.
The framework reduces the computational costs required for active control.
Characterization and modeling of an epoxy vitrimer based on disulfide exchange for wet filament winding applications
Authors: Lorenz N. , Zawadzki T. , Keller L. , Fuchs J. , Fischer K. , Hopmann Ch. 
Published: June 2024

AbstractThe present paper investigates the suitability of a vitrimeric epoxy resin for processing in the wet filament winding (WFW) process to manufacture fiber‐reinforced polymers (FRP). Comprehensive material characterization of a commercially available epoxy and vitrimeric resin based on disulfide exchange is carried out, and the processing in WFW is evaluated by analyzing thermomechanical, rheological, thermochemical properties, and chemical shrinkage. The direct comparison of a vitrimer and an established epoxy resin permits an indication of the processability and necessary adjustments in WFW. Based on the implications of modeling, we demonstrate the processing of the vitrimeric resin in the WFW process by increasing the resin bath temperatures. The vitrimer's and conventional resin's elastic modulus development and compression behavior were similar, highlighting the vitrimeric resin's potential. Further, the results confirm that established characterization and modeling routines can be transferred to vitrimeric resins and, therefore, path the way toward advanced process simulation of vitrimeric resin's processing. For this, the present publication gives essential advice for setting up testing schedules for characterizing epoxy vitrimers' processing behavior and their appropriate modeling. The present work underlines the potential of applying commercially available dynamic hardeners to manufacture recyclable and malleable FRP in established processes.Highlights
Material characterization and modeling of wet filament winding process.
Wet filament winding of epoxy vitrimers.
Thermomechanical and chemical shrinkage characterization of epoxy vitrimers.
Rheological and kinetic modeling of epoxy vitrimer.
Enhanced melt flow UHMWPE/HDPE blends melt spinning and performance study
Authors: Wang Gonghao , Liu Jie , Qin Shengxue , Zhang Hongbin , Zhou Haiping 
Published: June 2024

AbstractThe extremely low melt flowability of ultra‐high molecular weight polyethylene (UHMWPE) is the primary obstacle to its melt processing. Particularly in melt spinning processes, the extremely high molecular weight of UHMWPE and the density of entangled molecular chains severely limit its production efficiency and monofilament performance. This study investigates the effect of flow modifiers on the melt spinning process of UHMWPE/HDPE blends, focusing on CaSt2, PEG, and CaSt2/silicone powder composite additives, and their impact on the standard tensile samples and monofilament tensile properties of UHMWPE/HDPE. The mechanism of additive influence on the tensile properties of UHMWPE/HDPE blends is analyzed through tensile strength testing, thermal analysis, and microscopic morphology observation. The results show that in standard tensile samples, CaSt2 or CaSt2/silicone powder composite additives can enhance the crystallinity of the blend, thereby improving its tensile strength. Conversely, adding PEG significantly reduces the crystallinity and tensile strength of the blend. The maximum tensile strength of CaSt2‐modified UHMWPE/HDPE monofilament is 1236.61 MPa. This enhancement is attributed to the lubricating effect of CaSt2, which simultaneously assists the molecular chains in the amorphous region, and the reorientation of the stress‐induced molten lamellar structure under tension, greatly promoting the formation of straight‐chain crystals in the monofilament. During hot drawing, PEG inhibits the formation of straight‐chain crystals in the monofilament, resulting in a 3.06% decrease in maximum crystallinity compared with standard tensile samples. When CaSt2 is combined with silicone powder, the additives tend to aggregate during hot drawing, and these larger aggregate particles hinder the orientation of molecular chains along the drawing direction, resulting in a 30.75% decrease in maximum tensile strength of the monofilament compared with the standard tensile samples.Highlights
The tensile property of UHMWPE/HDPE blends modified with additives was discussed.
Analytical techniques including DSC, SEM, and tensile strength tests were used.
The maximum tensile strength of the monofilament can reach up to 1236.61 MPa.
UHMWPE/HDPE/CaSt2 = 60/40/0.5 exhibits the best tensile property.
Synthesis and properties of novel colorless polyimide containing indene and amide groups
Authors: Lu Zhaohui , Li Dongpeng , Gu Qian , Qian Guangtao , Li Dandan , Chen Chunhai 
Published: June 2024

AbstractTwo novel diamines 1‐(4‐aminophenyl)‐1,3,3‐trimethyl‐2,3‐dihydro‐1H‐indene‐5‐amine and 4‐amino‐N‐(4‐(5‐(4‐aminobenzamide)‐1,3,3‐trimethyl‐2,3‐dihydro‐1H‐inden‐1‐yl) phenyl) benzamide containing indene and amide groups were successfully designed and synthesized, and a series of colorless polyimides (CPIs) derived from the two diamines with 1,2,4,5‐cyclohexanetetracarboxylic dianhydride in various ratios were copolymerized. The introduction of aliphatic ring structures was conducive to the improvement of optical properties, while the incorporation of amide groups improved thermal and mechanical properties. These CPI films exhibited excellent optical properties (T400 > 80%), high heat resistance (Tg > 300 °C) and mechanical properties with the synergistic action of the two groups. Furthermore, the effect of the content of amide groups on the intermolecular interaction of CPIs was systematically analyzed. This study provides a fancy method for the development of heat‐resistant colorless materials for optical applications.
Validation of de novo designed water‐soluble and transmembrane β‐barrels by in silico folding and melting
Authors: Hermosilla Alvaro Martin , Berner Carolin , Ovchinnikov Sergey , Vorobieva Anastassia A. 
Published: June 2024

AbstractIn silico validation of de novo designed proteins with deep learning (DL)‐based structure prediction algorithms has become mainstream. However, formal evidence of the relationship between a high‐quality predicted model and the chance of experimental success is lacking. We used experimentally characterized de novo water‐soluble and transmembrane β‐barrel designs to show that AlphaFold2 and ESMFold excel at different tasks. ESMFold can efficiently identify designs generated based on high‐quality (designable) backbones. However, only AlphaFold2 can predict which sequences have the best chance of experimentally folding among similar designs. We show that ESMFold can generate high‐quality structures from just a few predicted contacts and introduce a new approach based on incremental perturbation of the prediction (“in silico melting”), which can reveal differences in the presence of favorable contacts between designs. This study provides a new insight on DL‐based structure prediction models explainability and on how they could be leveraged for the design of increasingly complex proteins; in particular membrane proteins which have historically lacked basic in silico validation tools.
Investigation of sensing behavior of carbon nitride (C6N8) for detection of phosphine (PH3) and phosphorous trichloride (PCl3): A DFT approach
Authors: Jamil Rabia , Saleem Uzma , Ahmed Hina , Nadeem Hafsah , Alghamdi Abeer Ahmed , Ayub Khurshid , Iqbal Javed 
Published: June 2024

AbstractThis study shows the exploration of the gas‐sensing capabilities of C6N8 material against toxic gases like phosphine (PH3) and phosphorous trichloride (PCl3). First‐principles study based on M05‐2X/LanL2DZ (d, p) method was performed to investigate the interaction energy (Eint.), frontier molecular orbitals (FMOs), natural bonding orbital (NBO), noncovalent interactions (NCIs), partial density of states (PDOS), molecular electrostatic potential (MEP), and quantum theory of atoms in molecules (QTAIM) analyses. The interaction energy results showed that PCl3@C6N8 (−23.45 kJ/mol) is more stable than PH3@C6N8 (−14.79 kJ/mol). A considerable decrease in the HOMO‐LUMO band gap of C6N8 was observed as a result of its complexation with the analytes. QTAIM and NCI analyses indicated the presence of weak noncovalent interactions between C6N8 and gases (PH3 and PCl3). SAPT0 analysis was performed to quantify the NCIs. MEP maps of complexes revealed the localization of electronic density on C6N8. The little recovery time of complexes (determined at 300 K) showed that C6N8 can serve as a reusable sensing material against PH3 and PCl3. Our results demonstrate that the C6N8 surface is a reliable material for detecting phosphine and phosphorous trichloride gases.
In Situ‐Tunable Spin–Spin Interactions in a Penning Trap with In‐Bore Optomechanics
Authors: Pham Joseph H. , Jee Julian Y. Z. , Rischka Alexander , Biercuk Michael J. , Wolf Robert N. 
Published: June 2024

AbstractExperimental implementations of quantum simulation must balance control‐field‐induced decoherence with the controllability of the quantum system. The ratio of coherent interaction strength to decoherence induced by stimulated emission in atomic systems is typically determined by hardware constraints, limiting the flexibility needed to explore different operating regimes. Here, an optomechanical system is presented for in situ tuning of the coherent spin‐motion and spin‐spin interaction strength in 2D ion crystals in a Penning trap. Enabled by precision closed‐loop piezo‐actuated positioners integrated into the confined space of a superconducting magnet's bore, the system allows tuning of the angle‐of‐incidence of Raman laser beams up to , governing the ratio of coherent to incoherent light‐matter interaction for fixed optical power. System characterization involves measurements of the induced mean‐field spin precession under the application of an optical dipole force in ion crystals cooled below the Doppler limit through electromagnetically induced transparency cooling. These experiments show approximately a variation in the coherent to incoherent interaction ratio with changing , consistent with theoretical predictions. The system stability is characterized over 6000 s, resulting in a drift rate of h–1. These technical developments will be crucial in future quantum simulations and sensing applications.
Bronchial occlusion with endobronchial Watanabe spigots using a two‐scope technique for massive haemoptysis
Authors: Baba Tomoya , Ito Takayasu , Sato Yoshiki , Hayai Shunsaku , Koyama Junji , Nakamura Shota , Tokuda Yoshiyuki , Chen‐Yoshikawa Toyofumi Fengshi , Ishii Makoto 
Published: June 2024

AbstractMassive haemoptysis is a life‐threatening condition whose cause needs to be identified rapidly so that prompt interventions can ensue. Bronchial occlusion with endobronchial Watanabe spigots (EWSs) may be useful when endovascular treatment or surgery proves to be difficult. An 84‐year‐old woman developed massive haemoptysis during percutaneous mitral valve repair for refractory heart failure due to severe mitral regurgitation (MR). Interventional radiology (IVR) and surgery were contraindicated, and bronchial occlusion with EWSs was attempted to control bleeding. The bleeding was so persistent that it was difficult to secure the visual field without aspiration with a bronchoscope. Herein, we report a two‐scope technique, also used in cryobiopsy of peripheral lung lesions, to control bleeding and perform bronchial occlusion with EWSs.
Leader‐following consensus control for feedforward nonlinear multiagent systems under DoS attacks with attack detection delays
Authors: Zhang Liuliu , Zhao Jiaao , Qian Cheng , Hua Changchun 
Published: June 2024

AbstractThis article investigates the leader‐follower consensus control problem of a feedforward nonlinear multiagent system under denial‐of‐service (DoS) attacks. Compared with the existing results on the consensus control of multiagent systems under DoS attacks, this article considers a class of feedforward multiagent systems with nonlinear functions that are less conservative, and takes into account asynchronous DoS attacks with attack detection delay. To address these problems, firstly, a new class of topological switching sequences and Laplacian matrices are designed based on the properties of the considered DoS attacks to convert the DoS attacks with attack detection delay problems into a class of topological switching problems. Then, a distributed dynamic gain compensator and an output feedback controller are constructed for each follower by using the output information of neighbor agents that are not intercepted by the attacks. Afterwards, by using piecewise Lyapunov functions, it is proven that if the DoS signal satisfies the condition of time‐varying average dwell time (ADT), then the followers can asymptotically track the state of the leader. Finally, a numerical example is provided to verify the effectiveness of the control algorithm.
Precision fabrication of polymer nanostructures on recyclable DNA template
Authors: Lin Zi'an , Xu Xuemei , Shi Yiwei , Wu Yuzhou 
Published: June 2024

AbstractThe fabrication of precisely patterned polymers at the nanoscale is of critical importance. We have previously succeeded in creating various nanopatterned polymers with nanoscale resolution through the use of in situ atom transfer radical polymerization (ATRP) techniques on deoxyribonucleic acid (DNA) origami. However, separating nanopatterned polymers from the origami template without damaging the origami presents a significant challenge, thereby increasing costs and limiting the development of applications involving nanopatterned polymers. Here, we achieved spatially and temporally controlled release of DNA origami templates through photo‐regulation by incorporating azobenzene‐modified DNA into the initiator. Under UV exposure, azobenzene isomerization rapidly induces the disassociation of patterned polymers from the origami template at ambient temperatures, without damaging the DNA origami. Additionally, the released origami template can be reused as a template for the cyclic production of nanopatterned polymers. This method provides a pathway for the large‐scale production of patterned polymers at reduced costs and facilitates dynamic control over the polymer‐DNA complex, with potential applications in both the biomedical and chemical fields.