bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evolution of the meta-neurosurgeon: A systematic review of the current technical capabilities, limitations, and applications of augmented reality in neurosurgery
Authors: Sharma Nikhil , Mallela Arka N. , Khan Talha , Canton Stephen Paul , Kass Nicolas Matheo , Steuer Fritz , Jardini Jacquelyn , Biehl Jacob , Andrews Edward G. 
Published: April 2024

Background:
Augmented reality (AR) applications in neurosurgery have expanded over the past decade with the introduction of headset-based platforms. Many studies have focused on either preoperative planning to tailor the approach to the patient’s anatomy and pathology or intraoperative surgical navigation, primarily realized as AR navigation through microscope oculars. Additional efforts have been made to validate AR in trainee and patient education and to investigate novel surgical approaches. Our objective was to provide a systematic overview of AR in neurosurgery, provide current limitations of this technology, as well as highlight several applications of AR in neurosurgery.

Methods:
We performed a literature search in PubMed/Medline to identify papers that addressed the use of AR in neurosurgery. The authors screened three hundred and seventy-five papers, and 57 papers were selected, analyzed, and included in this systematic review.

Results:
AR has made significant inroads in neurosurgery, particularly in neuronavigation. In spinal neurosurgery, this primarily has been used for pedicle screw placement. AR-based neuronavigation also has significant applications in cranial neurosurgery, including neurovascular, neurosurgical oncology, and skull base neurosurgery. Other potential applications include operating room streamlining, trainee and patient education, and telecommunications.

Conclusion:
AR has already made a significant impact in neurosurgery in the above domains and has the potential to be a paradigm-altering technology. Future development in AR should focus on both validating these applications and extending the role of AR.
Redefining cerebellar assessment: A comprehensive review of the cerebellum’s cognitive and affective roles and the efficacy of CCAS scales
Authors: Alan Albert , Ennabe Michelle , Alsarafandi Muath , Malik Noor , Laws Edward R. , Weinand Martin 
Published: April 2024

Background:
Emerging research expands our understanding of the cerebellum beyond motor control to include cognitive, emotional, and autonomic functions. This review examines the cerebellum’s complex role, spotlighting Schmahmann’s syndrome, or cerebellar cognitive affective syndrome (CCAS), which impairs executive functions, language, and spatial processing. It emphasizes advancements in diagnosing CCAS and the imperative of developing superior diagnostic tools for managing cerebellar pathologies effectively.

Methods:
A comprehensive literature search was performed using databases such as PubMed, OVID Embase, and OVID Medline. Using the keywords “cerebellar cognitive, affective syndrome” and “Schmahmann syndrome,” the search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines for systemic review, in which the selection process narrowed down an initial set of 54 articles to 12, focusing on the impact of the CCAS scale on diagnosing and understanding Schmahmann’s syndrome.

Results:
The review’s analysis confirms the cerebellum’s roles in motor and cognitive functions and underscores the CCAS scale as a significant advancement in detecting cerebellar deficits, surpassing traditional assessments such as the mini-mental state examination and Montreal cognitive assessment.

Conclusion:
This review emphasizes the importance of understanding the cerebellum’s involvement in cognition and emotion and the crucial role of the CCAS scale for identifying cerebellar impairments. It calls for better diagnostic tools to assess CCAS accurately and suggests enhancing the CCAS Scale to reflect cultural and educational diversity. This will improve the diagnosis and treatment of cerebellar disorders, promoting a comprehensive neurological perspective on the cerebellum’s functions.
Nuevos epítopes B y T, consenso de tropomiosina involucradas en reactividad cruzada entre diez especies diferentes. Un estudio in silico
Authors: Fang Luis , Martínez Dalgys , Meza-Torres Catherine , Moreno-Woo Ana , Pereira-Sanandres Nicole , Domínguez-Vargas Alex , Garavito Gloria , Egea Eduardo 
Published: April 2024

Introduction: tropomyosin is a pan-allergen that shows cross-reactivity between different species. In tropical countries, allergy to arthropods (mites, shrimp, cockroaches, mosquitoes) or nematodes (Ascaris spp) is common. IgE epitopes of tropomyosin may be the source of sensitization and the development of allergic symptoms. However, T epitopes (MHC-II) polarize the Th2 response.
Objective: This study aimed to identify by in silico methods tropomyosin consensus B and T epitopes of shrimp species, house dust mites, insects, and nematodes associated with allergic diseases in tropical countries.
Methods: in silico analysis included tropomyosin from mites (Der p 10, Der f 10, Blo t 10), insects (Aed a 10, Per a 7, Bla g 7), shrimp (Lit v 1, Pen m 1, Pen a 1), and nematode (Asc l 3); all sequences were taken from the UniProt database. Linear IgE epitopes were predicted with AlgPred 2.0 and validated with BepiPred 3.0. MHC-II binding T cell epitopes were predicted using the IEDB server, which implements nine predictive methods (consensus method, combinatorial library, NN-align-2.3, NN-align-2.2, SMM-align, Sturniolo, NetMHCIIpan -3.1, and NetMHCIIpan -3.2) these predictions focused on 10 HLA-DR and 2 HLA-DQ alleles associated with allergic diseases. Subsequently, consensus B and T epitopes present in all species were identified.
Results: we identified 12 sequences that behaved as IgE-epitopes and B-cell epitopes, three of them: 160RKYDEVARKLAMVEA174, 192ELEEELRVVGNNLKSLEVSEEKAN215, 251KEVDRLEDELV261 were consensus in all species. Eleven peptides (T-epitopes) showed strong binding (percentile rank ≤ 2.0) to HLA-DRB1*0301, *0402, *0411, *0701, *1101, *1401, HLA- DQA1*03:01/DQB1*03:02, and HLA- DQA1*05:01/DQB1*02:01. Only two T-epitopes were consensus in all species: 167RKLAMVEADLERAEERAEt GEsKIVELEEELRV199, and 218EEeY KQQIKT LTaKLKEAEARAEFAERSV246. Subsequently, we identified 2 B and T epitope sequences and reached a consensus between species 167RKLAMVEA174 and 192ELEEELRV199.
Conclusions: These data describe three sequences that may explain the IgE cross-reactivity between the analyzed species. In addition, the consensus B and T epitopes can be used for further in vitro investigations and may help to design multiple-epitope protein-based immunotherapy for tropomyosin-related allergic diseases.
Temephos Resistance Status of Aedes aegypti Populations From Havana, Cuba
Authors: Piedra Luis A. , Martinez Yanisley , Camacho Eric , Garcia Israel , Rodriguez Dayana , Vanlerberghe Veerle , Marquetti Maria Del Carmen 
Published: April 2024

ABSTRACT
Aedes aegypti chemical control remains an indispensable alternative to prevent dengue, Zika, and chikungunya outbreaks in Havana, Cuba. The city of Havana requires constant surveillance because of its bioecological characteristics that favor the proliferation of mosquito vectors of these viruses, which constitutes a high risk to the health of its inhabitants. The goal of this study was to determine the impact of the stopping of temephos applications during the 2 years of the COVID-19 pandemic on the level of susceptibility of Ae. aegypti in 5 municipalities of Havana, Cuba. Larval susceptibility was evaluated by bioassays as described by the World Health Organization. All Ae. aegypti populations tested showed high resistance to temephos. The National Control Program of Ae. aegypti in Cuba will need to promote insecticide rotation policies to prevent the evolution of temephos resistance in Havana.
Daya Matematis Siswa Kelas VIII dalam Memecahkan Masalah Geometri Ditinjau dari Taksonomi SOLO
Authors: Kusmaryono Imam 
Published: April 2024

Tujuan penelitian ini adalah menyelidiki adanya pencapaian KKM dari kemampuan daya matematis siswa kelas VIII dan menganalisa tingkat perkembangan kognitif dari kemampuan daya matematis siswa kelas VIII ditinjau dari Taksonomi SOLO. Penelitian menerapkan pendekatan kuantitatif. Penelitian dilaksanakan di SMP Islam Sultan Agung 4 Semarang. Populasi sebanyak 182 siswa kelas VIII. Melalui teknik cluster random sampling diperoleh kelas VIII-E (sebanyak 30 siswa) sebagai kelas eksperimen. Pembelajaran menerapkan model group investigation dengan materi geometri bangun ruang sisi datar. Instrumen penelitian meliputi soal tes tertulis.Â Hasil respon jawaban siswa dari tes daya matematika dianalisa berpanduan pada Structure of the Observed Learning OutcomesTaxonomy (SOLO).Â Hasil temuan penelitian menunjukkan (1)Â Tingkat Perkembangan kognitif daya matematis siswa kelas VIII dalam memecahkan masalah geometri ditinjau dari taksonomi SOLO belum sepenuhnya mencapai perkembangan kognitif tingkat permikiranÂ kualitatif (relational dan extended abstract), tetapi masih terdapat perkembangan kognitif tingkat pemikiran kuantitatif (uni-structural dan multi-structural); dan (2) Penerapan model pembelajaran group investigation efektif dalam pencapaian KKM daya matematis siswa kelas VIII pada materi geometri.Kata kunci: Daya matematis, mathematikal power, geometri, taksonomi SOLOÂ AbstractThe purpose of this study was to investigate the existence of the achievement of the KKM from the mathematical abilities of the eighth-grade students and to analyze the level of cognitive development of the eighth-grade students' mathematical abilities in terms of the SOLO taxonomy. This research applies a quantitative approach. The research was conducted at SMP Islam Sultan Agung 4 Semarang. The population was 182 students of class VIII. Through the cluster, random sampling technique, the VIII-E class (as many as 30 students) was obtained as the experimental class. Learning to apply the group investigation model with the geometry material of the flat side space shape. The research instrument includes written test questions. The results of student responses from the mathematics power test were analyzed based on the Structure of the Observed Learning OutcomesTaxonomy (SOLO). The results of the research findings show (1) the level of cognitive development of mathematical power of grade VIII students in solving geometry problems in terms of the SOLO taxonomy has not fully achieved cognitive development at the level of qualitative thinking (relational and extended abstract), but there is still cognitive development in the level of quantitative thinking (uni-structural). and multi-structural); and (2) The application of the group investigation learning model was effective in achieving the KKM of mathematical power of grade VIII students on geometry material.Keywords: Mathematical power, mathematical power, geometry, SOLO taxonomy
ESTRESSE, FATORES ASSOCIADOS E COPING ENTRE ESTUDANTES DO ENSINO MÉDIO: À LUZ DE BETTY NEUMAN
Authors: SILVA BARBOSA JEFFERSON , RIBEIRO DE VASCONCELOS ELIANE MARIA 
Published: April 2024

Objetivos: Identificar, na literatura, os principais fatores associados ao estresse e seu enfrentamento entre os estudantes do ensino médio na ótica da Teoria dos Sistemas Abertos de Betty Neuman Método: Trata-se se uma pesquisa do tipo revisão integrativa, que tem como finalidade a síntese de resultados obtidos em pesquisas sobre um tema pré-selecionado. Realizou-se a busca em seis bases de dados: LILACS, MEDLINE/Pubmed, CUIDEN, SCOPUS, ERIC E COCHRANE e a Scientific electronic library online (SciELO). Após critérios de inclusão e exclusão somaram-se 14 artigos para a pesquisa. Resultados : Foram encontrados como principais Fatores associados ao estresse a privação do sono, alimentação inadequada, Violência territorial, Práticas parentais prejudiciais, Falta de convívio familiar, Pressões acadêmicas e transição para a vida adulta. No tocante das Estratégias de enfrentamento evidencia-se as terapias alternativas, como musicoterapia e yoga, além da religiosidade, que pode promover bem-estar emocional. Essas práticas, quando integradas a um plano de cuidado abrangente, ajudaram os estudantes a lidar com o estresse e melhorar a qualidade de vida. Considerações finais: A Teoria dos Modelos dos Sistemas Abertos de Betty Neuman ajudou na compreensão dos estressores que os estudantes vivenciam, gerando conclusões mais precisas. Durante o ensino médio, desafios como privação de sono e alimentação afetam saúde física e mental, mas estratégias como musicoterapia e yoga promovem bem-estar.
The Influence Of Recruitment, Work Culture, And Work Environment On The Quality Of Human Resources At PT Gratia Jelajah Semesta
Authors: Handayani Putri , Pujiarti Pujiarti , Andy  
Published: April 2024

This study aims to test and determine the influence of recruitment, work culture, and work environment on employee performance at PT Gratia Jelajah Semesta. This study's sample included all company workers, with a total of 120 respondents. Data collection was carried out using questionnaires and the results were processed with SPSS 25 Analysis used using statistical models which include Frequency Test, Descriptive Test, Validity Test, Reliability Test, Determination Test (R2), T Test, and F Test. The results obtained partially stated that the recruitment variable (X1) had a significant effect with a sig value of 0.000 < 0.05 and tcount 14.261 > table 1.98, the variable X2 work culture had a significant effect on the value 18.603 > ttable 1.98, variable X3 work environment has a significant effect with calculated value < table 16.227 > 1.98. The results obtained simultaneously fcalculate > ftable 156.902 > 2.68 there is a joint influence.
Achieving good science
Authors: Pols Jeannette , M'charek Amade , Jerak-Zuiderent Sonja , Brenninkmeijer Jonna 
Published: April 2024

Abstract
There are worries about the quality of scientific research, the validity of the knowledge it produces and the integrity of academics. What is lacking in the debate is what scientists have to say and what they do to create and safeguard what they see as ‘good science’. Using Dutch academia as a case, we show that the academics’ understandings of scientific practice differ in vital ways from those of policy makers. Policy maker's understanding of academia as a competitive marketplace to foster innovative research disturbs the everyday ethics and creativity of scientific work according to the scientists, who see academia as a collective practice aimed at understanding the world in which tradition and innovation have to find a balance. We conclude that this misunderstanding and its consequences do more to damage research integrity than fraudulent activities of individual researchers.
Organizational sustainability to support Trusted Smart Statistics: Istat’s experience
Authors: De Cubellis Massimo , Grippo Gerarda 
Published: April 2024

The datification processes have driven National Statistical Institutes (NSIs) to explore new data sources with the goal of enhancing the quality of statistical information. The creation of innovative statistical products, known as Trusted Smart Statistics (TSS), necessitates new production processes that integrate with traditional methods, maintaining levels of relevance, quality, and trust. To facilitate this transition in statistical production, NSIs must embark on change management initiatives involving all organizational dimensions engaged in statistical processes. In the scientific debate, sustainability has assumed a broad connotation. This paper delves into the organizational aspect, viewing sustainability as a paradigm that encompasses all organizational areas and their interactions crucial to supporting the shift to new statistical production models, without compromising traditional practices. The paper explores the path taken by Istat in this direction, the organizational solutions implemented, the benefits realized, and investments in research and innovation initiated years ago on new data sources, aligning with developments in the European statistical community. Istat has been at the forefront of big data experimentation in Europe for over a decade, implementing a modernization program and establishing research infrastructures. Istat took a significant step by founding the TSS Center to guide organizational adaptation at technological, methodological, legal, communication, and human resources levels toward the new production system.
Pengelolaan Kurikulum Operasional Madrasah di MAN 1 Kota Bekasi
Authors: Wulandari Apriyanti , Hasan Basri Husen , Saimroh Saimroh 
Published: April 2024

Â Abstract
The learning load for madrasas is greater because it accommodates the curriculum program set by the Ministry of Education, Culture, Research and Technology plus a curriculum program related to Islamic religious content set by the Ministry of Religion. This high learning load is carried out in accordance with regulations from the center without any adjustments according to the resources and orientation of education services in each madrasah. This study aims to examine curriculum management which includes planning, implementation, and evaluation at MAN 1 Bekasi City. The results of the research found that curriculum management at MAN 1 Bekasi City was still focused on implementation that had not been well planned and evaluation based on problems. The operational curriculum that has been prepared does not yet describe the practice of educational services carried out at MAN 1 Bekasi City. Input the results of the study to MAN 1 Bekasi City as a proposal to improve curriculum documents.
KOMUNIKASI EFEKTIF PEMERINTAH DAERAH DENGAN DPRD DALAM PEMBENTUKAN PERATURAN DAERAH DI KABUPATEN TIMOR TENGAH UTARA
Authors: Kehik Bernardus Seran , Kalembang Elpius 
Published: April 2024

Dasar dari komunikasi efektif adalah adanya komunikasi timbal balik yang dilakukan oleh komunikator dengan komunikan dalam pengiriman pesan, dengan memperhatikan isi pesan yang disampaikan baik melalui media komunikasi maupun melalui pesan secara langsung. Pola hubungan Pemerintah Dewan Perwakilan Rakyat Daerah diperlukan komunikasi yang efektif dalam penyelenggaraan pemerintahan daerah guna mencapai tujuan kegiatan pambangunan yang dilaksanakan. Komunikasi antara Pemerintah Daerah dengan DPRD yang kurang baik berdampak pada kinerja kedua lembaga tersebut. Produk kebijakan public yang mereka hasilkan bersama menjadi kurang efektif karena dalam proses pembahasannya bisa terganjal hal-hal yang bersifat non teknis. Persoalan komunikasi yang timbul biasanya disebabkan antara lain oleh permasalahan legitimasi, ego sektoral lembaga, pemahaman terhadap tugas dan fungsi yang keliru, konflik politik karena ego sektoral yang masih melekat pada Esekutif dan Legislatif. Peneliti menyimpulan bahwa komunikasi efektif guna membangun pola hubungan sejajar antara Pemerintah Daerah dengan DPRD di Kabupaten Timor Tengah Utara selama ini dapat berjalan dengan baik. Walaupun dalam komunikasi efektif tersebut terdapat muatan kepentingan politik partai yang cukup kental dari masing-masing lembaga.
PENERAPAN SISTEM APLIKASI E - ARSIP PADA KEGIATAN PENGARSIPAN SURAT- MENYURAT DIBAGIAN UMUM SEKRETARIAT DAERAH KABUPATEN ACEH BARAT
Authors: Asrat Elisa 
Published: April 2024

Penelitian ini bertujuan untuk mengetahui tentang pemanfaatan alat elektronik dilingkup istansi pemerintahan, Salah satunya pemanfaatan komputer dibagian umum setdakab aceh barat dalam hal kegiatan pengarsipan surat masuk dan surat keluar dengan menerapkan sistem aplikasi web yang dikenal dengan E-Arsip. Penerapan sistem E-arsip ini dinilai sudah cukup baik dan efesien dalam memberikan pelayanan, yang mana dapat dirasakan berdasarkan kecepatan, keamanan kinerja pegawai. Akan tetapi masih dijumpai kendala- kendala pada sistem aplikasi tersebut dalam kegiatan pengarsipan surat sehari hari. Penelitian ini mengunakan teori William H. DeLone dan Ephraim R. McLean (1992). Metode dalam Penelitian ini mengunakan evaluasi bersifat kualitatif yaitu menganalisis, memotret, dan menggambarkan kondisi kerja pegawai dibidang pengarsipan surat masuk dan surat keluar dibagian umum lingkup setdakap aceh barat, sesuai dengan hasil wawancara, pengumpulan data, serta observasi lapangan dapat disarankan penulis agar sistem aplikasi e-arsip ini harus terus diterapkan dalam memberikan pelayanan, bahkan bila perlu lebih dikembangkan lagi dan merancang sistem aplikasi E-arsip dalam hal kegiatan pengarsipan surat masuk dan surat keluar yang lebih terbaru sehinga dapat meminimalisir kendala yang ada agar proses kegiatan pengarsipan surat lebih efektif dan efesien dari sebelumnya.
DAMPAK KONSTRUKSI GENDER TERHADAP ANGKA PARTISIPASI SEKOLAH PEREMPUAN
Authors: Bitin Berek Hendrika Jelia , Kehik Bernardus Seran , Kalembang Elpius 
Published: April 2024

Hasil Penelitian menunjukkan bahwa dampak konstruksi terhadapa angka partisipasi sekolah perempuan di Desa Kletek disebabkan oleh beberapa faktor yaitu pengetahuan masyarakat mengenai gender masih sangat rendah. Selain dipengaruhi oleh pengetahuan masyarakat tentang gender masih sangat rendah, dipengaruhi juga oleh pola pikir masyarakat terhadap perempuan. Banyak anggapan yang dibangun di dalam masyarakat bahwa tugas utama perempuan adalah mengurus rumah tangga sehingga berpengaruh terhadap tingkat partisipasi sekolah kaum perempuan di Desa Kletek. Selain itu juga peran laki-laki lebih diutamakan daripada perempuan baik dalam hal adat maupun dalam kebiasaan sehari-hari. Sehingga menyebabkan tingkat partisipasi sekolah untuk kaum perempuan di Desa ini masih lebi rendah daripada laki-laki. Dengan hasil kesimpulan di atas, maka penulis menyarankan bahwa: perlu ditingkatkan pengetahuan masyarakat tentang gender dengan cara melakukan sosialisasi secara rutin kepada masyarakat untuk dapat mengubah pola pikir masyarakat terhadap perempuan.
Kata kunci: Dampak, Konstruksi Sosial, Gender, Perempuan, Desa Kletek
KESETARAAN GENDER DALAM BUDAYA PATRIARKI TERHADAP KAUM PEREMPUAN PADA RANAH PUBLIK (KETERLIBATAN PEREMPUAN DALAM PEMILIHAN KEPALA DESA PERIODE 2016-2021)
Authors: PENU YULITA HENDERINA 
Published: April 2024

Tujuan penelitian Ini adalah untuk mengetahui sejauh mana perempuan terlibat dalam pemelihan Kepala Desa Seperti Terlibat Dalam: Pembentukan Panitia, kampanye dan pengumutan suara di Desa Fatumnutu Kecamatan Polen Kabupaten Timor Tengah Selatan. Metode Penelitian Yang digunakan adalah metode yang bersifat Deskriptif Kualitatif. Dan sumber data dalam penelitian ini menggunakan data primer dan data sekunder. Hasil penelitian menunjukan bahwa: Keterlibatan Perempuan dalam tahap–tahap proses pemilihan Kepala desa mulai dari tahap pemebentukan panitia, hingga hasil penetapan hasil pemilihan kepala desa dalam pembentukan panitia dilibatkan. Ada beberapa kendala yang di alami pada saat pemilihan kepala desa yaitu pengaruh budaya patriarki, perempuan tidak mencalonkan diri dalam pemilihan Kepala desa, dan tingkat pemahaman kaum perempuan dalam proses pemilihan kepala Desa Periode 2016-2021 di Desa Fatumnutu Kecamatan Polen Kabupaten Timor Tengah Selatan masih rendah.
Peneliti kepada kaum perempuan Di desa Fatumnutu agar kedepanya perempuan harus diikut sertakaan dalam mencalonkan diri sebagai kepala desa bukan hanya laki-laki yang berkuasa tetapi kaum perempuan juga mempunyai hak untuk berpolitik. Disaran kanjuga agar perempuan tidak berpegaruh dengan budaya patriarki sehingga perempuan juga setara dengan laki-laki dalam ranah publik.