bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic and morphometric characterization of a local Vietnamese Swamp Buffalo population
Authors: Berthouly C. , Rognon X. , Nhu Van T. , Berthouly A. , Thanh Hoang H. , Bed’Hom B. , Laloë D. , Vu Chi C. , Verrier E. , Maillard J.‐C. 
Published: September 2009

SummaryThe water buffalo plays a key role in the socio‐economy of South‐East Asia as it is the main draught power for paddy rice cultivation. While in the Indian subcontinent the water buffalo is the riverine type, in South‐East Asia the majority of buffaloes are of the swamp type. In the poor remote northern province of Ha Giang in Vietnam, improvement of the swamp buffalo breed may be one of the best ways to increase sustainability of farming systems. Therefore, analysis of the genetic structure of the province buffalo population is a prerequisite to any conservation or improvement project. A total of 1122 animals were described for 11 body and horn measurements for morphometric characterization. From this sample set, 744 animals were genotyped for 17 microsatellite markers. Also 17 animals from southern provinces of Vietnam were genotyped as a comparative sample. The results showed that genetic diversity as well as inbreeding value in the Ha Giang was high. The FST values within the province and across Vietnam were low indicating that most of the population variation is explained by individual variability. Bayesian clustering analysis did not highlight the presence of subdivided populations. These results are useful for the implementation of a conservation and improvement strategy of the swamp buffalo in order to guarantee the householders’ needs for sustainability of the farming system in the Ha Giang province.
Database on diagnosis of arthropod diseases in the Internet of the Julius Kühn‐Institute
Authors: Kleespies R. G. , Huger A. M. , Zimmermann G. 
Published: September 2009

AbstractA database on diagnosis of diseases of insects and other arthropods is available in a German and English version at http://arthropodenkrankheiten.jki.bund.de. It is based on 55 years of diagnostic investigations of living, diseased, or dead arthropods of about 450 species at the ‘Institute for Biological Control’ in Darmstadt, Germany. Results of 1951 accessions with several thousands of diagnosed specimens from 1953 to 2008 are presented. The diagnosed pathogens belong to six groups: viruses, bacteria including rickettsiae, fungi, microsporidia (recently assigned to fungi), protists, and nematodes. The database will be updated regularly.
Review article: Kidney dendritic cells: Their role in homeostasis, inflammation and transplantation
Authors: ROGERS NATASHA M , MATTHEWS TYSON J , KAUSMAN JOSH Y , KITCHING RICHARD A , COATES P TOBY H 
Published: September 2009

SUMMARY:There is definitive experimental proof that a lattice of dendritic cells (DC) exist within the renal parenchyma. Kidney‐resident DC (KDC) are an important constituent of passenger leucocytes that initiate the direct component of allograft rejection in transplantation and form a central element of the innate immune response following injurious stimuli to the kidney. DC are recruited to the kidney in pathophysiological states such as glomerulonephritis and ischaemia–reperfusion injury. However, the exact mechanism for engaging and attracting DC to infectious and transplant antigens, and whether specific DC subsets are involved remains unresolved. In addition, the extent to which resident and infiltrating DC contribute to the propagation of injury or rejection is also unclear. Despite consistently expanding published work regarding DC location, phenotype and function, there are a number of deficiencies in our knowledge base, particularly in relation to KDC.
Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis
Authors: MIKI Keisuke , MAEKURA Ryoji , HIRAGA Toru , HASHIMOTO Hisako , KITADA Seigo , MIKI Mari , YOSHIMURA Kenji , TATEISHI Yoshitaka , FUSHITANI Kenji , MOTONE Masaharu 
Published: September 2009

ABSTRACTBackground and objective:  Exertional dyspnoea limits patients with IPF in their activities of daily living. The mechanism, however, has not been elucidated. This study tested the hypothesis in IPF that exertional dyspnoea correlates with cardiopulmonary exercise responses, specifically changes in arterial blood pH and plasma norepinephrine (NE).Methods:  Cardiopulmonary exercise testing with measurements of dyspnoea (Borg scale), plasma NE, plasma lactate and arterial blood gases were performed in 29 patients with IPF and in nine controls.Results:  Both groups showed obvious break points in dyspnoea changes during exercise. In IPF, an abrupt change in the Borg scale, pH, PaCO2 and plasma NE occurred in the late exercise phase after the ‘break point’. Compared with controls, patients with IPF had significantly higher HCO3‐ levels and physiologic dead space/tidal volume during exercise. In IPF, during both exercise phases, the dyspnoea slope (ΔBorg scale/Δminute ventilation) correlated with the pH slope (ΔpH/Δoxygen uptake) (before the break point: r = −0.537, P = 0.0022; r = −0.886, P < 0.0001, after the break point) and the NE slope (ΔNE/Δoxygen uptake) (before the break point: r = 0.481, P = 0.0075; R = 0.784, P < 0.0001, after the break point).Conclusions:  In patients with IPF, exercise‐induced acidosis and increases in circulating NE levels were associated with intensity of exertional dyspnoea.
The current role of thoracic surgery in tuberculosis management
Authors: SIHOE Alan D.L. , SHIRAISHI Yuji , YEW Wing Wai 
Published: September 2009

ABSTRACTAlthough tuberculosis is mainly managed medically today, thoracic surgery continues to play a key role in its diagnosis and treatment in selected subgroups of patients. In certain scenarios such as multi‐drug‐resistant tuberculosis, advanced tuberculous empyema and symptomatic bronchial stenosis, modern thoracic surgery may represent the only effective means of management in selected patients. Advances in thoracic surgery in recent years, in particular the use of Video‐Assisted Thoracic Surgery, not only reduce postoperative morbidity for individual patients, but may potentially allow a wider range of tuberculosis patients to benefit from surgery. Respiratory physicians and thoracic surgeons should continue to work together to ensure that tuberculosis patients who may benefit from surgery are identified for prompt and effective intervention.
Ameloblastoma of the mandible with pulmonary metastases 45 years after initial diagnosis
Authors: PAPAIOANNOU Maria , MANIKA Katerina , TSAOUSSIS Bassilis , CHEVA Angeliki , SICHLETIDIS Lazaros , KIOUMIS John 
Published: September 2009

ABSTRACTAmeloblastoma of the mandible is a rare odontogenic tumour that rarely metastasizes. We report a patient with a slowly progressing ameloblastoma of the mandible diagnosed at the age of seven and resected multiple times due to tumour recurrence. Multiple pulmonary metastatic nodules were resected at thoracotomy 27 years after the initial diagnosis; however, further pulmonary disease was discovered. The patient was admitted with chest pain due to pulmonary metastases 45 years after the initial diagnosis. The metastases were intraluminal and could be attributed to tumour cell aspiration during the surgical procedures on the mandible. The patient also suffered from hypercalcaemia which was attributed to a parathormone‐like substance secreted by the tumour.
Diagnosing fibrotic lung disease: When is high‐resolution computed tomography sufficient to make a diagnosis of idiopathic pulmonary fibrosis?
Authors: SCHMIDT Shelley L. , SUNDARAM Baskaran , FLAHERTY Kevin R. 
Published: September 2009

ABSTRACTIdiopathic pulmonary fibrosis (IPF), a progressive and fatal diffuse parenchymal lung disease, is defined pathologically by the pattern of usual interstitial pneumonia (UIP). Unfortunately, a surgical lung biopsy cannot be performed in all patients due to comorbidities that may significantly increase the morbidity and mortality of the procedure. High‐resolution computed tomography (HRCT) has been put forth as a surrogate to recognize pathological UIP. The quality of the HRCT impacts the ability to make a diagnosis of UIP and varies based on the centre performing the study and patient factors. The evaluation of the HRCT includes assessing the distribution and predominance of key radiographical findings, such as honeycomb, septal thickening, traction bronchiectasis and ground glass attenuation lesions. The combination of the pattern and distribution is what leads to a diagnosis and associated confidence level. HRCT features of definite UIP (subpleural, basal predominant honeycomb with septal thickening, traction bronchiectasis and ground glass attenuation lesions) have a high specificity for the UIP pathological pattern. In such cases, surgical lung biopsy can be avoided. There are caveats to using the HRCT to diagnose IPF in isolation as a variety of chronic pulmonary interstitial diseases may progress to a UIP pattern. Referral centres with experience in diffuse parenchymal lung disease that have multidisciplinary teams encompassing clinicians, radiologists and pathologists have the highest level of agreement in diagnosing IPF.
Temporal stage and grade migration in surgically treated patients with upper tract urothelial carcinoma
Authors: Lughezzani Giovanni , Jeldres Claudio , Isbarn Hendrik , Sun Maxine , Shariat Shahrokh F. , Widmer Hugues , Arjane Philippe , Graefen Markus , Perrotte Paul , Montorsi Francesco , Karakiewicz Pierre I. 
Published: September 2009

Study Type – Therapy (individual cohort) Level of Evidence 2bOBJECTIVETo examine the temporal trends in stage and grade at presentation, as well as cancer‐specific mortality (CSM) rates, in surgically treated patients with upper tract urothelial carcinoma (UTUC), as few population‐based studies addressed contemporary cancer‐control outcomes in patients with UTUC.PATIENTS AND METHODSWithin the Surveillance, Epidemiology and End Results (SEER) database, we identified 4915 patients diagnosed with UTUC between 1983 and 2004, who had either a nephroureterectomy (NU) or a segmental ureterectomy (SU). Patients were divided into four groups according to the year‐of‐surgery quartiles. The chi‐square test and the chi‐square trend test were used for comparison of proportions and trends over time. Kaplan‐Meier plots were used to graphically depict CSM rates. Multivariable Cox regression models were used to test the effect of the year‐of‐surgery quartiles on CSM. Covariates consisted of SEER stage, tumour grade, age, race, primary tumour site, type of surgery, and SEER registries.RESULTSOf 4915 assessable patients, 1316, 1328, 1146 and 1125 were, respectively, treated in 1983–1988, 1989–94, 1995–99 and 2000–2004. Of those, 4430 had a NU and 485 had a SU. The rates of non‐localized stage and of grade III‐IV disease at surgery increased, respectively, from 49.8% to 69.5% (P < 0.001) and 45.7 to 70.2% (P < 0.001) during the study period. CSM rates at 4 years after surgery reflected the temporal stage and grade differences, and increased from 18.2 to 23.9% (P = 0.03) between 1983–1988 and 2000–2004. In multivariable analyses, when stage and grade were taken into account, most contemporary patients showed more favourable CSM rates than their historic counterparts (hazard ratio 0.7, P = 0.02).CONCLUSIONSWe report a stage and grade migration at NU or SU towards more aggressive disease among surgically treated patients between 1983 and 2004. Despite this observation, the CSM rates of contemporary patients have not worsened, which validates the role of NU and SU as effective treatments for UTUC.
Is the incidence of uretero‐intestinal anastomotic stricture increased in patients undergoing radical cystectomy with previous pelvic radiation?
Authors: Katkoori Devendar , Samavedi Srinivas , Adiyat Kishore Thekke , Soloway Mark S. , Manoharan Murugesan 
Published: September 2009

Study Type – Therapy (case series) Level of Evidence 4OBJECTIVETo present our long‐term experience comparing uretero‐intestinal anastomotic (UIA) stricture rates after radical cystectomy (RC) in patients with and without previous pelvic radiotherapy (pRT), as the risk of stricture is thought to be higher in patients undergoing RC and urinary diversion (UD) with a history of pRT.PATIENTS AND METHODSWe retrospectively analysed patients who had RC and UD between 1992 and 2008 by one surgical team. Patients were divided into two groups, those with (group 1) and with no (group 2) previous pRT. Relevant clinical and pathological data were entered into a database. Patients who were symptomatic and required intervention for a UIA stricture were analysed; patients with malignant strictures were excluded.RESULTSIn all, 526 patients had RC by one surgical team during the study period; 65 had pRT before RC, 37 for prostate cancer, 23 for bladder cancer and the rest for other pelvic malignancies. All the patients in group 1 had an ileal conduit (IC) diversion. There were 250 IC and 211 neobladder diversions in group 2. There were 130 (12%) UIAs in group 1, vs 922 (88%) in group 2. There was no statistically significant difference between the groups in demographic profile and follow‐up. The overall stricture rate for UIA was 1.3%; there were two (1.5%) UIA strictures in group 1 vs 12 (1.3%) in group 2. The mean (median, range) time to onset of the stricture was 10 (6, 2–39) months. There was no statistically significant difference in stricture rate between the groups (P > 0.05).CONCLUSIONSIn patients undergoing RC with UD there was no significant difference in UIA stricture rates between those with and without previous pRT.
Auditory verb perception recruits motor systems in the developing brain: an fMRI investigation
Authors: James Karin Harman , Maouene Josita 
Published: September 2009

AbstractThis study investigated neural activation patterns during verb processing in children, using fMRI (functional Magnetic Resonance Imaging). Preschool children (aged 4–6) passively listened to lists of verbs and adjectives while neural activation was measured. Findings indicated that verbs were processed differently than adjectives, as the verbs recruited motor systems in the frontal cortex during auditory perception, but the adjectives did not. Further evidence suggested that different types of verbs activated different regions in the motor cortex. The results demonstrate that the motor system is recruited during verb perception in the developing brain, reflecting the embodied nature of language learning and processing.
Fertility needs and funding in couples with blood‐borne viral infection
Authors: Kalu E , Wood R , Vourliotis M , Gilling‐Smith C 
Published: September 2009

BackgroundCouples infected with HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) are increasingly seeking assisted conception. These couples avoid unprotected intercourse and use condoms at all times in order to minimize the risk of infecting their partner. As this practice inhibits pregnancy, assisted procreation is generally required for safe conception. For many couples, access to such services is restricted on ethical, geographical and financial grounds.ObjectiveThe aim of the study was to assess the fertility needs, geographical origin and state funding of patients with blood‐borne viral infection.MethodsA retrospective review of the medical records of couples referred for fertility treatment between January 1999 and December 2006, where one or both partners were infected with HIV, HBV and/or HCV, was carried out.ResultsOf the 205 couples included in the study, 44% lived in London, 51% came from elsewhere in the United Kingdom and 5% travelled from outside the United Kingdom to seek treatment. Genitourinary medicine clinics were the main source of referral. 85.8% of couples had HIV infection, 15.1% were infected with HBV and 13.6% had HCV infection. Fertility screening identified a high incidence of male factor infertility (33.3%) in HIV‐infected men and tubal disease (40.8%) in HIV‐infected women. Only 23.6% of HIV‐infected couples, 20% of HBV‐infected couples and 12.5% of HCV‐infected couples obtained state funding for assisted conception.ConclusionFertility screening identified a high incidence of male and tubal factor subfertility among couples living with HIV, HBV and HCV. Limited access to specialist clinics equipped to cater for these couples and restricted funding may impact negatively on couples obtaining risk‐reducing assisted reproduction treatment. This may have long‐term public health implications as individuals attempt to conceive through unprotected intercourse.
Toward a More Embedded Production System? Automotive Supply Networks and Localized Capabilities in Poland
Authors: DOMAŃSKI BOLESŁAW , GWOSDZ KRZYSZTOF 
Published: September 2009

ABSTRACTThe article addresses the embeddedness of automotive production in Poland in terms of supply networks. A comprehensive analysis of more than 550 suppliers, supported by company interviews, shows that foreign‐owned producers become embedded in Poland in the automotive supplier networks they have largely created themselves. Numerous local suppliers gain access to export markets and become integrated in a Europe‐wide production system. This trend has been accompanied by significant upgrading of foreign affiliates and domestic firms in terms of product quality, cost efficiency, adaptability, and fast response, but far less in nonproduction competences such as R&D. It is argued that the competences of automotive suppliers in Poland are built upon the localized capabilities, which are a product of the dynamic interplay between the activity of foreign firms and the changing local environment comprising various stakeholders. The localized capabilities constitute elements of a company's sunk costs and are embedding automotive producers in Poland. At the same time, the dependence on decisions and innovations from abroad and the limited development of local design and brands may constrain the future role of suppliers from the semiperipheral economy of Poland.
Environmental Protection and Impact on Adjacent Economies: Evidence from the Swedish Mountain Region
Authors: LUNDGREN TOMMY 
Published: September 2009

ABSTRACTThe study presented here considers the effects of protected land on neighboring local economies, based on a panel data analysis of its influence on economic growth, net migration, and employment in the forest and tourism sectors in 15 municipalities in northwestern Sweden from 1985 to 2001. The main findings are that increases in the area of protected land in this region seem to have promoted slight increases in per capita income growth and net migration, slight reductions in employment in the forest sector, and possible increases (not significant at the 5 percent probability level) in employment in the tourism sector. In addition, there are indications of conditional divergence in the Swedish mountain region, implying that small economies grow more slowly here than larger economies.
Assemblages of Justice: The ‘Ghost Ships’ of Graythorp
Authors: HILLIER JEAN 
Published: September 2009

AbstractI investigate the issue of dismantling the so‐called ‘ghost’ ships in Graythorp, Hartlepool, as an episode of relational forging of space and contestation between constructs of social and environmental justice. I offer a Deleuzoguattarian‐inspired cartography, tracing constructions of justice, injustice and nature with regard to both Hartlepool and the wider issue of ship dismantling. I explore tensions and commonalities between expressed concerns, as actants discursively seek to reconfigure relational space in the name of social and/or environmental justice. Amongst the generative flux of complex, dynamic forces and relations which become folded together, the complexity of spatial planning decision making emerges as an oscillation between relations of presence and absence, which planners attempt to mediate in constructing some singular form of ‘just’ decision. Yet this is but one choice among many: of social justice? Of environmental justice? To which actants? Across which spaces?Résumé Cet article considère le problème du démantèlement des ‘navires fantômes’ sur le site de Graythorp (Hartlepool) comme un épisode dans le façonnage relationnel de l'espace et de la contestation entre les notions de justice sociale et de justice environnementale. Il propose une cartographie inspirée par Deleuze et Guattari, qui repère les constructions de justice, d'injustice et de nature par rapport à Hartlepool et au problème plus vaste du démantèlement des navires. Sont analysés les tensions et points communs entre les préoccupations exprimées, les différents actants cherchant à reconfigurer l'espace relationnel au nom de la justice sociale et/ou environnementale. Dans le ‘flux génératif’ des relations et forces dynamiques complexes qui sont ainsi incorporées ensemble, la complexité de la prise de décision en matière d'aménagement spatial se dessine comme une oscillation entre des liens de présence et d'absence, les aménageurs tentant d'arbitrer en élaborant une forme singulière de ‘juste’ décision. Pourtant, ce n'est qu'une option parmi beaucoup d'autres : de justice sociale? de justice environnementale? à l'égard de quels actants? au sein de quels espaces?
Association of seborrhoeic warts with skin cancer in renal transplant recipients**
Authors: Lally A , Casabonne D , Waterboer T , Imko‐Walczuk B , Michael KM , Pawlita M , Newton R , Wojnarowska F 
Published: September 2009

AbstractBackground  Renal transplant recipients (RTR) have a well recognized increased risk of cutaneous malignancy. A clinical observation that RTR with skin cancer often had multiple seborrhoeic warts prompted an investigation in RTR into the relationship between seborrhoeic warts and skin cancer and an exploration into potential risk factors for seborrhoeic warts in this population, including infection with human papillomavirus (HPV).Methods  This was a case control study involving 308 RTR. Clinical examinations identified seborrhoeic warts. Histological records reviewed to look for evidence of prior cutaneous malignancy. Seroprevalence of antibodies to 34 different HPV types tested using multiplex serology. Odds ratios (OR) calculated using unconditional logistic regression analysis to look for associations between skin cancer, HPV infection and seborrhoeic warts, controlling for potential confounding factors of gender, age and time since transplantation.Results  Seborrhoeic warts were associated with non‐melanoma skin cancer [OR = 3.7; 95% confidence intervals (CI) ranging from 1.6–8.9; P = 0.002] when confounding factors of gender, age and time since transplantation were controlled for. There was also an association between seborrhoeic warts and viral warts (OR = 3.0, CI: 1.6–5.4; P < 0.0001), but no association between seborrhoeic warts and infection with single or multiple HPV types.Conclusions  Seborrhoeic warts are associated with cutaneous malignancy, but not with any of the HPV types tested. The reasons for this association are unclear. RTR with multiple seborrhoeic warts may require more regular cutaneous examination to monitor for early signs of skin cancer.