bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, attitudes, and practices among the general community population toward heatstroke
Authors: Xu Yangfeng , Chen Jianping , Du Jinkang , Jin YunYing 
Published: May 2024

Background and objectiveHeatstroke (HS) is a life-threatening condition resulting from thermal injury within the body, and it is associated with a significantly high mortality rate. This study aimed to assess the knowledge, attitudes and practices (KAP) among the general community population toward heatstroke.MethodsThe web-based cross-sectional study was conducted between September 2023 and October 2023 at the Emergency Department of Dongyang People's Hospital. A self-designed questionnaire was developed to collect demographic information of the general community population and to assess their knowledge, attitudes and practices toward heatstroke.ResultsA total of 1,356 valid questionnaires were collected. Among the participants, 875 (64.53%) were female, and 496 (36.58%) had regular exercise. The mean knowledge, attitudes and practices scores were 12.73 ± 1.42 (possible range: 0–14), 33.74 ± 2.91 (possible range: 8–40) and 34.65 ± 5.30 (possible range: 8–40), respectively. The structural equation model demonstrated that education had direct effects on knowledge (β = 0.017, p &lt; 0.001), attitudes (β = 0.123, p &lt; 0.001), and practices (β = −0.094, p &lt; 0.001). Moreover, knowledge had direct effects on attitudes (β = 1.920, p &lt; 0.001), and attitudes had direct effects on practices (β = 0.642, p &lt; 0.001).ConclusionThe findings revealed that the general community population have sufficient knowledge, active attitudes and proactive practices toward the heatstroke. However, there is still room for improvement and it is necessary to develop and implement educational initiatives and interventions designed to further enhance their KAP toward heatstroke.
Does volunteering decrease burnout? Healthcare professional and student perspectives on burnout and volunteering
Authors: Metzger Tai , Nguyen Nathan , Le Hillary , Havo Daisy , Ngo Katherine , Lee Sebastian , Nguyen Timmy , Nguyen Quynhanh , Tran Leyna , Tong Nathan , Le Collin , Dudovitz Rebecca 
Published: May 2024

BackgroundBurnout among healthcare providers is a significant crisis in our healthcare system, especially in the context of the COVID-19 pandemic. The aim of this study was to understand what motivates healthcare workers and students to volunteer in their community as well as examine how volunteering relates to burnout. These findings can help health organizations better meet the needs of healthcare workers, as well as provide insights for non-profits that rely on volunteer professionals.MethodsHealthcare providers (N = 8), graduate healthcare students (N = 10), and undergraduate students (N = 14) who volunteered at community health fairs completed the OLBI burnout assessment and an individual semi-structured interview to characterize their attitudes toward volunteering and its relationship with burnout. Interviews were recorded, transcribed, and analyzed using a phenomenological approach, comparing themes across levels of burnout among providers and students.ResultsParticipants described that feeling burnt out decreased one’s likelihood to volunteer, but also that volunteering prevented burnout. The OLBI scores showed that 79.2 and 20.8% of students were low and moderately burnt out respectively, and 87.5 and 12.5% of health professionals were low and moderately burnt out, respectively. Students volunteered for professional development while healthcare professionals cited a desire for a change in their day-to-day work as a reason to volunteer. Both students and health professionals often volunteered because they wanted to make a difference, it made them feel good, and/or they felt a responsibility to volunteer. COVID-19 had a wide range of effects on burnout and motivations to volunteer.ConclusionVolunteering may be useful for preventing burnout among healthcare workers and students, but may not be helpful for those already experiencing burnout. Interview responses and the fact that none of the volunteers had high burnout levels according to their OLBI scores suggest those who choose to volunteer may be less burnt out. Healthcare organizations and schools can encourage volunteering by emphasizing the difference healthcare students and professionals can make through volunteering in the community. Increasing convenience and emphasizing professional development can help recruit and retain healthcare student volunteers. Highlighting the chance to diversify their scope of practice may help recruit and retain healthcare professional volunteers.
Evaluation of activation characteristics of a canine platelet concentrate produced by a commercial double centrifugation system
Authors: Tey Nicole , Koenig Amie , Hodges Katie , Brainard Benjamin M. 
Published: May 2024

IntroductionIn veterinary medicine there are few readily available products for platelet transfusion to patients with thrombocytopenia. Commercial tabletop platelet concentrating systems have recently become available to veterinarians, primarily directed towards uses associated with regenerative medicine. These systems could potentially be used to produce fresh concentrated platelets for use in transfusion medicine. This study evaluated the concentration, activation, and sterility of a double centrifugation platelet concentrate (PC) produced by a commercial benchtop system.MethodsTen healthy dogs were studied. Whole blood was collected and mixed with ACD-A in a 1:7.6 ratio of ACD-A to whole blood. 12 mL of this mixture was processed into PC via single centrifugation, while 60 mL of the anticoagulated whole blood was processed via a commercial double centrifugation system. Both types of PC were evaluated for platelet concentration, CD62P expression with and without thrombin stimulation, and for sterility.ResultsMean platelet count in the double centrifuged PC was 863 ± 352 × 103/μL, with very low white blood cell contamination (median of 0.47 × 103 leukocyte/μL (range 0.15–2.18 × 103/μL)). The double-centrifuged PC had similar baseline activation characteristics (as determined by P-selectin expression) as the single centrifuge PC (0.76% vs. 0.72% unstimulated, 30.5% vs. 34.9% stimulated, p = 0.432).DiscussionThe benchtop PC system studied here did not cause activation of platelets during production and produced a sterile product that can be further investigated as a source of fresh platelet concentrates for transfusion purposes.
Estudo de alimentos denominados “naturais” para cães comercializados em Florianópolis - SC
Authors: Miranda Danielli Pinheiro , Hauptli Lucélia , Lima André Luis Ferreira , Moraes Priscila de Oliveira , Miotto Marília , Thaines Luiza , Rossignatti Bruna Queiros 
Published: May 2024

O objetivo do estudo foi avaliar alimentos considerados “naturais”, para cães comercializados em Florianópolis – SC, em relação a conformidade com a legislação, composições nutricionais (para proteína bruta, extrato etéreo, fibra bruta, matéria mineral, cálcio e fósforo), informações nos rótulos e qualidade microbiológica. Os alimentos foram divididos em dois grupos: com e sem fabricante registrado no Ministério da Agricultura, Pecuária e Abastecimento (MAPA). As análises nutricionais foram comparadas com os níveis mínimos de exigências das tabelas de referência oficiais utilizadas para formulações de dietas para cães. A comparação destes dados entre os dois grupos foi realizada por análise de variância com nível de 5% de significância. Foram identificados sete alimentos, quatro com fabricante registrado no MAPA e três sem registro. Dos alimentos com registro, um destes, não atendeu completamente aos itens necessários no rótulo. Dos alimentos sem registro, nenhum atendeu completamente à legislação, faltando em torno de 60% das informações. Os resultados das análises dos nutrientes nos sete alimentos não mostraram diferenças (P>0,05) e apresentaram valores dentro dos níveis recomendados por tabelas de exigências oficiais. A exceção dos níveis de cálcio que foram diferentes entre os alimentos com (1,5%) e sem registro de fabricante (0,06%). A média do Ca nos alimentos sem registro foi muito menor que o mínimo exigido para um cão adulto (0,6%). Dos quatro alimentos com registro ocorreram situações de níveis nutricionais e de matéria seca analisados diferentes dos declarados no rótulo. Nas análises microbiológicas, houve ausência de Salmonella spp. e baixa prevalência de coliformes nos sete alimentos. Houve ocorrência maior que aceitável de bolores e leveduras em cinco dos setes alimentos. Conclui-se que os alimentos denominados naturais comercializados Florianópolis – SC para cães, que não tem registro no MAPA não apresentam informações exigidas por lei em seus rótulos. Os níveis nutricionais analisados dos alimentos, com e sem registro, estão de acordo com as tabelas oficiais de exigências nutricionais dos cães, a exceção do Ca que estava abaixo do exigido nos alimentos sem registro. Dos quatro alimentos com registro de fabricante ocorreram situações de níveis nutricionais e de matéria seca analisados diferentes dos declarados no rótulo. A qualidade microbiológica pode ser considerada satisfatória, a exceção de bolores que apresentaram alta incidência em cinco alimentos analisados.
Nota Editorial
Authors: Hernández Quintero Juan Esteban 
Published: May 2024

Nota Editorial

Se presenta en este número el resultado del trabajo realizado por autores en Chile, Rusia, Costa Rica, Argentina, Ecuador y México. Los tópicos que aborda este número incluyen sismología, que representa un riesgo para la población. El tema aborda un llamado al uso de sistemas de alertamiento, y al estudio profundo del comportamiento de la sismicidad en diversas áreas del planeta. Así mismo, la aplicación de la prospección geo-eléctrica nos brinda una herramienta de gran utilidad en la mitigación de riesgos de carácter ambiental; además de un recurso para cuantificar la saturación del agua subterránea, un recurso vital que debe ser considerado estratégico.
En un ejercicio de análisis en la reseña incluida en este número, se demuestra que los esfuerzos trans e interdisciplinarios representan un panorama prometedor para abordar temas extensos y ciertamente complejos. En la reseña “exploraciones del mundo subterráneo. Un acercamiento al Gran Acuífero Maya”, se devela la gran variedad de proyectos ligados a un solo objetivo: analizar la sociedad que conformó el antiguo mundo maya, el cuál actualmente está conformado por cinco países, y que, en el conocimiento actual, abarca 500,000 kilómetros cuadrados, incluyendo los grandes centros de desarrollo en Palenque, Calakmul, Tikal y Copán.
Los artículos presentados en este número 70 siguen demostrando el abanico de temas de riesgo en nuestras sociedades; la importancia de la geofísica en el ámbito de la mitigación y prevención no deja de ser primordial. Por otro lado, la capacidad de los métodos geofísicos para analizar las sociedades del pasado, enriquece el acervo de conocimiento de los países miembros.
Se cumple una vez más, uno de los objetivos del Instituto Panamericano de Geografía e Historia, que consiste en la difusión del conocimiento y del trabajo que los profesionales en las Ciencias de la Tierra desarrollan en diversas entidades generadoras de conocimiento. El intercambio de experiencias en temas específicos, fomenta las relaciones entre los países de América, y del mundo entero.

El Editor
Resolución de parámetros del terremoto del 3 de marzo de 1985 a partir de la distribución de las deformaciones
Authors: Araneda Manuel , Avendaño María Soledad , Kausel Edgar 
Published: May 2024

Variaciones de elevación registradas mediante medidas geodésicas, cambios de la componente vertical de la gravedad y observaciones directas de solevantamientos costeros, asociados al terremoto del 3 de Marzo de 1985 cuya magnitud fue Ms=7.8, permitieron obtener un modelo estático de dislocación de la falla que ajusta adecuadamente con la ubicación de los hipocentros de las replicas.
El modelo consta con un segmento de falla con pendiente de 5° hacia el este, que se hace más inclinado en profundidad (22°- 25°) con deslizamiento de 0.4 a 0.6 m en la parte superficial y 1.8 a 2.1 m en la sección mas profunda. Estos resultados concuerdan con soluciones dinámicas obtenidas por otros autores e indican que gran parte del momento sísmico proviene de los tramos más profundos de la falla, donde se han encontrado las replicas de mayor magnitud.
Variaciones relativas de la gravedad observadas antes y después del terremoto indican que la ruptura se extendió hasta algo más al sur de Pichilemu. La información es insuficiente para estimar el límite norte de la ruptura.
Analisis Faktor Yang Mempengaruhi Aktivitas Instrumen Derivatif Valuta Asing Sebagai Pengambilan Keputusan Hedging (Studi Kasus Pada Perusahaan Sub Sektor Batubara Yang Terdaftar Di Bei Periode 2017-2021)
Authors: Daffa Fadhlurrahman Hartadi  , Utami Kery 
Published: May 2024

Hedging merupakan salah satu alternatif manajemen risiko yang bertujuan untuk melindungi aset perusahaan dari kerugian. Tujuan penelitian ini adalah untuk menganalisis pengaruh variabel independen yang meliputi Likuiditas, Leverage, Ukuran Perusahaan, dan Kepemilikan Manajerial terhadap keputusan lindung nilai dengan menggunakan instrumen derivatif pada perusahaan batubara yang terdaftar di Bursa Efek Indonesia tahun 2017-2021. Metode pemilihan sampel yang digunakan dalam penelitian ini adalah metode purposive sampling dengan ketentuan perusahaan yang menerbitkan laporan keuangan lengkap dimana terdapat 16 perusahaan. Penelitian ini menggunakan teknik analisis regresi logistik, untuk menemukan sekumpulan variabel yang mempengaruhi probabilitas penggunaan instrumen derivatif sebagai aktivitas lindung nilai. Hasil penelitian ini menemukan bahwa: (1) variabel Leverage dan Ukuran Perusahaan berpengaruh positif dan signifikan terhadap keputusan lindung nilai dengan menggunakan instrumen derivatif dan (2) Likuiditas dan Kepemilikan Manajerial berpengaruh negatif dan tidak signifikan terhadap keputusan lindung nilai dengan menggunakan instrumen derivatif.

Kata kunci: Likuiditas, leverage, Ukuran Perusahaan, dan Kepemilikan Manajerial
Drag of electron–hole bilayer in silicon-on-insulator metal-oxide-semiconductor field-effect transistor at low temperature
Authors: Ahmed Nabil , Razanoelina Manjakavahoaka , Hori Masahiro , Fujiwara Akira , Ono Yukinori 
Published: May 2024

Abstract
Drag between the electron and the hole layers formed in a silicon-on-insulator MOSFET, with the estimated interlayer distance as small as 18 nm, is investigated. The drag resistance is measured at 10 K and mapped on the plane defined by the electron and hole densities. Analysis shows that the Coulomb drag predominates over the competing virtual-phonon drag. The observed drag resistance is as large as 103-104 Ω, indicating strong Coulomb interaction between the electron and hole layers.
Relevancia Social de una Nueva Carrera en una Zona Manufacturera Catalogada con Pobreza en Amozoc, Puebla
Authors: Apan Araujo Giovana Lizet , Apan Araujo Karla Cecilia , Flores Cajica Sirenia Dolores , Flores Ramírez Óscar 
Published: May 2024

Un estudio sobre la factibilidad de la apertura de una nueva licenciatura dentro de una isntitución educativa permite dar una respuesta directa, relevante y eficaz a las problematicas y necesidades presentes en nuestra sociedad actual. Por lo que el objetivo fue estudiar la pertinencia socioal de la propuesta de una nueva licenciatura en Amozoc, Puebla, México, para garantizar su efecto positivo en la región. Dicho estudio se realizó desde Noviembre de 2023 hasta Febrero de 2024, se aplicaron 1390 cuestionarios a estudiantes de educación media superior prontos a ingresar a una formación de educación superior, estas herramientas contenian 28 preguntas para conocer el contexto social de los encuestados y de sus preferencias educativas; así mismo se realizo una reunión de “Análisis Situacional del Trabajo”. La estadística fue descriptiva. Se encontró que los intereses universitarios de los aprendientes corresponden a dar respuesta a las necesidades que observan en su región, como lo son lo relacionado con la industria atomotriz y mecánica, además de esta responder a lo evaluado en la AST.
Ameloblastic Fibro-odontoma - A Case Report of Two Uncommon Cases
Authors: Jihed Sghaier , Slim Afef , Charfeddine Abir , Smida Abdelkader , Abdellatif Chokri , Selmi Jamil 
Published: May 2024

Abstract

Rationale:
Ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumour with a preferential location in the posterior mandible and with a variety of radiological aspects. We report two clinical cases of AFO in two rare locations and with unusual radiological aspects.

Patient Concerns:
The first patient is a 37-year-old female with an asymptomatic intraoral swelling located in the anterior mandibular. The second patient is a 16-year-old girl with a chief complaint of missing maxillary canine.

Diagnosis:
Both cases were diagnosed with AFO.

Treatment:
For the first patient, a biopsy was performed, and for the second one, the lesion was surgically excised.

Outcomes:
The first patient is under regular surveillance and the other was followed up for one year without any evidence of recurrences.

Take-away Lessons:
Despite many efforts, the nature, histology and therapy of these lesions remain very confusing.
Characteristic Differences between Freeze-dried Tenogenic Secretomes and Freeze-dried Crude Secretomes of Mesenchymal Stem Cells under Hypoxic Conditions
Authors: Kresnadi Agus , Edward Mouli , Khang Gilson , Suroto Heri 
Published: May 2024

ABSTRACT

Introduction:
Tendons that are crucial for movement are struggling with self-healing. Regenerative medicine has been using mesenchymal stem cells (MSCs) and their secretomes, and it offers promise. These secretomes, rich in growth factors, aid tissue healing. Tenogenic secretomes target tendon-specific healing, while crude ones provide a broader view of MSC signaling. The study aims to enhance targeted interventions in tendon regeneration and improve the quality of life for those with tendon-related issues.

Methods:
This laboratory study compares freeze-dried tenogenic and crude secretomes of MSCs under hypoxic conditions for regenerative potential. Stem cells from adipose tissue undergo isolation, culture, and multiplication then treated in hypoxic conditions. Characterization, Interleukin-6 (IL-6) and Interleukin-10 (IL-10) analysis with enzyme-linked immunosorbent assay (ELISA) follow. The results, including organoleptic, pH, and scanning electron microscope assessments, were presented descriptively. Statistical analysis will enhance understanding.

Results:
Physical characteristics (odor, color, and pH) are similar in both groups. Tenogenic secretome has a more concave surface, potentially aiding cell migration compared to the crude secretome. There were significant differences in cytokine levels (P = 0.001). IL-6 levels expressed from tenogenic secretome were 10.2 ± 2.432 pg/mL compared to the crude one which 18.3 ± 3.175 pg/mL. Levels of IL-10 expressed from tenogenic and crude secretomes were 309.2 ± 50.973 pg/mL and 200.1 ± 32.030, respectively.

Conclusion:
The tenogenic secretome and crude secretome exhibit no differences in physical characteristics but differ in surface morphology. The concave surface of the tenogenic secretome facilitates cell migration more than the crude secretome. Under hypoxic conditions, the tenogenic secretome shows lower pro-inflammatory (IL-6) and higher anti-inflammatory (IL-10) effects than the crude secretome.
The effect of viral hepatitis B and C on the outcome of allogenic bone marrow transplantation of patients with adult acute myeloid leukemia (Egyptian sample)
Authors: Shazly Mohamed A , Azzazi Mohamed O , Mousa Mohamed M , Soliman Raafat A , Alnakeeb Sarah A E K , Sultan Almetwaly M 
Published: May 2024

Abstract

Background
Hematopoietic stem cell transplantation is now established as a standard therapeutic modality for different malignant and benign diseases. Hematopoietic stem cell transplantation has many complications. Infection and graft-versus-host disease (GVHD) remain the major source of morbidity and mortality in patients who undergo BMT.

Aim
The aim of this work was to investigate the effect of hepatitis B and hepatitis C (HCV) viral infection on the outcome of fully matched sibling donor peripheral blood stem cell transplantation in patients with acute myeloid leukemia (AML).

Patients and methods
A total of 328 patients with AML who received allogeneic PBSC transplantation using BU/CY or FLU/BU conditioning regimen after the consent of the Ethical Committee of Nasser Institute Hospital during the period from 1997 to December 2016 were included in this study with a follow-up of 12 months.

Results
In seropositive patients, neutrophil engraftment was reached at a median of 14.57 days and platelet engraftment was reached at a median of 12.7. However, in seronegative patients, neutrophil engraftment was reached at a median of 14.3 (P=0.287) and platelet engraftment was reached at a median of 12.66 (P=0.917). In seropositive patients, the incidence of SOS was 2.1%, acute GVHD grades 2–4 was reported in eight patients, whereas chronic GVHD was reported in nine patients. In seronegative patients, the incidence of SOS was 0.70% (P=0.33), acute GVHD grades 2–4 was reported in 30 patients (P=0.184), whereas chronic GVHD was reported in 45 patients (P=0.54). Overall survival for HCV seronegative and seropositive patients was 58.4 and 44.6%, respectively (P=0.001), whereas disease-free survival for HCV seronegative and seropositive patients was 56.9 and 43.4%, respectively (P=0.0001).

Conclusion
Analysis of 46 HCV-positive adult AML patients and 282 HCV seronegative patients who had peripheral blood stem cell transplantation shows that HCV infection does not affect platelet or neutrophil engraftment or the incidence of SOS. HCV viremia did not show a significant effect on the incidence of acute and chronic GVHD. We also documented that there is a significant effect of HCV on both the disease-free survival and overall survival.
Relation of junctional adhesion molecule-a in multiple myeloma patients with possible prognostic factors
Authors: Shaaban Ingy Ossama Ahmed , Sultan Hala K , Sultan Magda M , Gammal Maha M A El , Balbaa Ola A 
Published: May 2024

Abstract

Background
Multiple myeloma (MM) is a clonal plasma cell disorder characterized by the abnormal increase of monoclonal paraprotein leading to specific end-organ damage. Drug resistance is one of the major challenges in treating MM. As an emerging cell adhesion-mediated drug resistance (CAM-DR) agent, JAM-A (Junctional adhesion molecule-A), represents an exciting new potential drug target and biomarker for treating MM. However, the pathological role and clinical relevance of JAM-A in MM remains ambiguous.

Aim
To study the relation of JAM-A expression levels in MM patients with possible prognostic factors.

Patients and methods
The study was carried out on a total of 100 subjects divided into two groups. The first group included 50 multiple myeloma patients, while the second group included 50 patients performing aspiration of bone marrow for other conditions with normal plasma cell percentage. All subjects in the current study were subjected to full history taking and complete clinical examination, radiological studies, routine laboratory investigations, bone marrow aspiration/ biopsy, immunophenotyping, measurement of serum IL-6 levels and estimation of JAM-A expressions by Quantitative real-time PCR.

Results
JAM-A was overexpressed in newly diagnosed MM patients compared with post-treated patients and control group. Moreover, high JAM-A expression levels showed statistically significant correlations with plasma cell percentage in BM, serum β2-microglobulin and serum IL-6 levels.

Conclusion
JAM-A is overexpressed in MM and could be used as innovative prognostic biomarker.