bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A General Strategy for the Convergent Synthesis of Fused Polycyclic Ethers via B‐Alkyl Suzuki Coupling: Synthesis of the ABCD Ring Fragment of Ciguatoxins.
Authors: Sasaki Makoto , Ishikawa Makoto , Fuwa Haruhiko , Tachibana Kazuo 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxygen Compounds of Halogens X2O2 (X Is a Halogen Atom)
Authors: Nikitin I. V. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Non‐Covalent Synthesis of Metallodendrimers
Authors: van Manen Henk‐Jan , van Veggel Frank C. J. M. , Reinhoudt David N. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tripodal Triamidometallates of the Heavy Group 14 Elements: Inorganic Cages with Remarkable “Ligand Properties”
Authors: Gade Lutz H. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed α‐Arylation of Esters: Ideal New Methodology for Discovery Chemistry
Authors: Lloyd‐Jones Guy C. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermal [1,3] Carbon Sigmatropic Rearrangements of Vinylcyclobutanes
Authors: Leber Phyllis A. , Baldwin John E. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Surface Chemistry of Catalysis: New Challenges Ahead
Authors: Zaera Francisco 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A new view of diffusion in nanoporous materials
Authors: Kärger J. , Chmelik C. , Heinke L. , Valiullin R. 
Published: May 2010

AbstractDiffusion is among the rate‐controlling processes in the technological application of nanoporous materials, including separation and conversion processes. Over decades, the different techniques of diffusion measurements yielded controversial results. The benefit of novel measuring techniques which, by immediate visual evidence, exemplify the self‐consistency of the resulting diffusivities is shown. Furthermore, by quantifying the permeabilities through the particle surfaces and by correlating the rate of molecular uptake and release with the molecular mobilities, these techniques are able to identify and to explore additional transport resistances which so far, though being rate‐limiting in numerous cases, were outside the range of direct experimental observation.
Charakterisierung mesoporöser Materialien mittels Kleinwinkelstreuung (SAXS/SANS)
Authors: Smarsly B. M. , Mascotto S. , Weidmann C. , Kaper H. 
Published: May 2010

AbstractMesoporöse Materialien zeigen abhängig von der Homogenität der Porenstruktur mitunter sehr verschiedenartige Kleinwinkelstreu‐Kurven. Die elementaren Grundlagen der Kleinwinkelstreuung sowie prinzipielle Auswertungsansätze für mesoporöse Materialien mit geordneter und ungeordneter Porenmorphologie werden erläutert. Das Anpassen der kompletten Streukurve führt zu einer umfassenden Charakterisierung der Proben, wobei zwei verschiedene Ansätze verfolgt werden: für geordnete und ungeordnete Porenstrukturen. Für letztere ist das Konzept der Segmentlängenverteilung („chord‐length distribution”︁) eine geeignete Methode, wesentliche Informationen zur Porosität aus scheinbar strukturlosen SAXS/SANS‐Daten zu erhalten.
Two‐part regression models for longitudinal zero‐inflated count data
Authors: Alfò Marco , Maruotti Antonello 
Published: May 2010

AbstractTwo‐part models are quite well established in the economic literature, since they resemble accurately a principal‐agent type model, where homogeneous, observable, counted outcomes are subject to a (prior, exogenous) selection choice. The first decision can be represented by a binary choice model, modeled using a probit or a logit link; the second can be analyzed through a truncated discrete distribution such as a truncated Poisson, negative binomial, and so on. Only recently, a particular attention has been devoted to the extension of two‐part models to handle longitudinal data. The authors discuss a semi‐parametric estimation method for dynamic two‐part models and propose a comparison with other, well‐established alternatives. Heterogeneity sources that influence the first level decision process, that is, the decision to use a certain service, are assumed to influence also the (truncated) distribution of the positive outcomes. Estimation is carried out through an EM algorithm without parametric assumptions on the random effects distribution. Furthermore, the authors investigate the extension of the finite mixture representation to allow for unobservable transition between components in each of these parts. The proposed models are discussed using empirical as well as simulated data. The Canadian Journal of Statistics 38: 197–216; 2010 © 2010 Statistical Society of Canada
Estimating functions for evaluating treatment effects in cluster‐randomized longitudinal studies in the presence of drop‐out and non‐compliance
Authors: Yi Grace Y. , Cook Richard J. , Chen Baojiang 
Published: May 2010

AbstractWe describe methods for analyzing longitudinal binary data from cluster‐randomized trials in which responses are incompletely observed and subjects may not be fully compliant with the prescribed treatment regimen. The method is based on a marginal regression model for the response where parameter estimates are obtained from generalized estimating equations. Estimating equations are also employed to estimate parameters of the missing data process which are used to compute inverse probability weights. A model is specified for the compliance process which facilitates estimating the expectation of the contributions to the estimating function for the response parameters among individuals without compliance data, which occurs when the control treatment involves no intervention. The approach is robust in the sense that semi‐parametric models are used for the response and the missing data processes and robust variance estimates are advocated. The proposed method is shown to perform well in simulation studies, and data from a randomized trial of patients with depression are analyzed for illustration. The Canadian Journal of Statistics 38: 232–255; 2010 © 2010 Statistical Society of Canada
Unusual Anion Effects in the Iron‐Catalyzed Formation of 3‐Hydroxyacrylates from Aromatic Aldehydes and Ethyl Diazoacetate
Authors: Alves Luis Gonçalo , Dazinger Georg , Veiros Luis F. , Kirchner Karl 
Published: May 2010

AbstractDue to the lability of one of the CO ligands in trans‐[Fe(PNP)(CO)2Cl]+ this compound is an efficient catalyst for the coupling of a series of aromatic aldehydes with ethyl diazoacetate (EDA), which give, in most cases, selectively 3‐hydroxyacrylates rather than β‐oxo esters. This reaction is strongly dependent on the nature of the counterion. Whereas with BF4– the reaction proceeds with conversions up to 90 %, in the case of the counterions NO3–, CF3COO–, CF3SO3–,SbF6–, and BAr′4– [Ar′ = 3,5‐(CF3)2C6H3] no reaction took place. In the case of PF6– only up to 20 % conversion was achieved. A conceivable mechanism for the coupling of aromatic aldehydes with EDA was established by means of DFT/B3LYP calculations, which allowed the rationalization of both the chemoselectivity and the role of the counterions.
Free‐flow electrophoresis in the proteomic era: A technique in flux
Authors: Islinger Markus , Eckerskorn Christoph , Völkl Alfred 
Published: May 2010

AbstractSince its introduction five decades ago, free‐flow electrophoresis (FFE) has been mainly employed for the isolation and fractionation of cells, cell organelles and protein mixtures. In the meantime, the growing interest in the proteome of these bio‐particles and biopolymers has shed light on two further facets in the potential of FFE, namely its applicability as an analytical tool and sensor. This review is intended to outline recent innovations, FFE has gained in the proteomic era, and to point out the valuable contributions it has made to the analysis of the proteome of cells, sub‐cellular organelles and functional protein networks.
Three‐dimensional velocity mapping of thoracic aorta and supra‐aortic arteries in takayasu arteritis
Authors: Amano Yasuo , Takagi Ryo , Suzuki Yuriko , Sekine Tetsuro , Kumita Shinichiro , van Cauteren Marc 
Published: May 2010

AbstractTakayasu arteritis is an inflammatory disease of unknown etiology that involves the aorta, its major branches, and the pulmonary artery. We describe three patients with Takayasu arteritis who showed abnormal velocity profile of the thoracic aorta and supra‐aortic arteries on time‐resolved three‐dimensional (3D) phase‐contrast MR imaging and velocity mapping techniques. Compared with two comparative subjects, velocity reduction was observed in these arteries. The velocity reduction was prominent along the thickened arterial wall, even with normal luminal caliber, and the highest velocity was observed on the contralateral side. In one patient, the arterial flow velocity and its profile at systole were partly improved after the treatment. The time‐resolved 3D velocity mapping visualized the changes in the blood velocity profile at systole in Takayasu arteritis. J. Magn. Reson. Imaging 2010;31:1481–1485. ©2010 Wiley‐Liss, Inc.
Pain related to rotator cuff abnormalities: MRI findings without clinical significance
Authors: Bencardino Jenny T. , Beltran Luis S. 
Published: May 2010

AbstractMRI has become an important diagnostic tool in the evaluation of rotator cuff pathology and the technology continues to evolve. Direct MR arthrography, diagnosis‐specific sequencing such as fat suppression, special positioning such as abducted externally rotated (ABER) views and ultra high field magnets allow for an unprecedented level of detail in imaging. In this article, we review MRI findings in patients with rotator cuff abnormalities that are anatomic variants or incidental findings. Although MRI findings may be diagnostic in some cases, we find that clinical correlation with history and physical examination is critical to differentiate between anatomic variants, incidental findings, and true pathology. We conclude that good communication between the orthopedic surgeon and the radiologist is necessary to optimize diagnostic yield. J. Magn. Reson. Imaging 2010;31:1286–1299. © 2010 Wiley‐Liss, Inc.
Improved pseudo‐continuous arterial spin labeling for mapping brain perfusion
Authors: Nezamzadeh Marzieh , Matson Gerald B. , Young Karl , Weiner Michael W. , Schuff Norbert 
Published: May 2010

AbstractPurpose:To investigate arterial spin labeling (ASL) methods for improved brain perfusion mapping. Previously, pseudo‐continuous ASL (pCASL) was developed to overcome limitations inherent with conventional continuous ASL (CASL), but the control scan (null pulse) in the original method for pCASL perturbs the equilibrium magnetization, diminishing the ASL signal. Here, a new modification of pCASL, termed mpCASL is reported, in which the perturbation caused by the null pulse is reduced and perfusion mapping improved.Materials and Methods:improvements with mpCASL are demonstrated using numerical simulations and experiments. ASL signal intensity as well as contrast and reproducibility of in vivo brain perfusion images were measured in four volunteers who had MRI scans at 4 Tesla and the data compared across the labeling methods.Results:Perfusion maps with mpCASL showed, on average, higher ASL signal intensity and higher image contrast than those from CASL or pCASL. Furthermore, mpCASL yielded better reproducibility in repeat scans than the other methods.Conclusion:The experimental results are consistent with the hypothesis that the new null pulse of mpCASL leads to improved brain perfusion images. J. Magn. Reson. Imaging 2010;31:1419–1427. © 2010 Wiley‐Liss, Inc.
Brain iron detected by SWI high pass filtered phase calibrated with synchrotron X‐ray fluorescence
Authors: Hopp Karla , Popescu Bogdan F.Gh. , McCrea Richard P.E. , Harder Sheri L. , Robinson Christopher A. , Haacke Mark E. , Rajput Ali H. , Rajput Alex , Nichol Helen 
Published: May 2010

AbstractPurpose:To test the ability of susceptibility weighted images (SWI) and high pass filtered phase images to localize and quantify brain iron.Materials and Methods:Magnetic resonance (MR) images of human cadaver brain hemispheres were collected using a gradient echo based SWI sequence at 1.5T. For X‐ray fluorescence (XRF) mapping, each brain was cut to obtain slices that reasonably matched the MR images and iron was mapped at the iron K‐edge at 50 or 100 μm resolution. Iron was quantified using XRF calibration foils. Phase and iron XRF were averaged within anatomic regions of one slice, chosen for its range of iron concentrations and nearly perfect anatomic correspondence. X‐ray absorption spectroscopy (XAS) was used to determine if the chemical form of iron was different in regions with poorer correspondence between iron and phase.Results:Iron XRF maps, SWI, and high pass filtered phase data in nine brain slices from five subjects were visually very similar, particularly in high iron regions. The chemical form of iron could not explain poor matches. The correlation between the concentration of iron and phase in the cadaver brain was estimated as cFe [μg/g tissue] = 850Δϖ + 110.Conclusion:The phase shift Δϖ was found to vary linearly with iron concentration with the best correspondence found in regions with high iron content. J. Magn. Reson. Imaging 2010;31:1346–1354. © 2010 Wiley‐Liss, Inc.
JCV/BKV and SV40 viral load in lymphoid tissues of young immunocompetent children from an area of North‐East Italy
Authors: Comar Manola , Zanotta Nunzia , Bovenzi Massimo , Campello Cesare 
Published: May 2010

AbstractPolyomavirus infection occurring during childhood is followed by a lifelong latency in immunocompetent subjects. The major site of polyomavirus persistence are the uroepithelial cells which leads to oral transmission. It has recently been hypothesized that tonsils could be a possible reservoir. The role of tonsil, adenoid, and peripheral blood mononuclear cells (PBMCs) as possible sites of JCV, BKV, and SV40 latency in young healthy children was assessed. Two hundred fifteen fresh specimens, including 57 tonsil, 80 adenoid, and 78 PBMC samples from 80 immunocompetent children (mean age 4.8 years) were analyzed to determine the viral load by quantitative real‐time PCR. The human herpes virus 6 (HHV‐6) was tested as a lymphotropic reference virus. Polyomavirus was detected in 5/80 (6.2%) children while HHV‐6 infection affected 27/80 children (33.7%) (P < 0.001). SV40 was detected in one adenoid sample, while footprints of BKV were found in one adenoid and three tonsil samples. JCV was never found in all samples. Polyomavirus sequences were not detected in the 78 blood samples. One adenoid and two tonsils from three children (1.4%) were positive for both polyomavirus and HHV‐6. Infections were characterized by low replication rates ranging typically from 1 × 10e2/5.5 × 10e4 to 6.8 × 10e3/8.5 × 10e4 viral copies/number of cells. In conclusion, tonsils and adenoids of children could effectively harbor BKV and SV40, although only very few cells proved to be infected. Nevertheless, the low prevalence of polyomavirus, in comparison with the lymphotropic HHV‐6, suggests that these tissues are unlikely to be the preferred site of polyomavirus latency, at least in younger children. J. Med. Virol. 82:1236–1240, 2010. © 2010 Wiley‐Liss, Inc.
Phylogeny and resistance profiles of HIV‐1 POL sequences from rectal biopsies and blood
Authors: Katzenstein T.L. , Petersen A.B. , Storgaard M. , Obel N. , Jensen‐Fangel S. , Nielsen C. , Jørgensen L.B. 
Published: May 2010

AbstractThe phylogeny and resistance profiles of human immunodeficiency virus type 1 (HIV‐1) protease (PR) and reverse transcriptase (RT) sequences were compared among six patients with HIV‐1 who had received numerous treatments. RNA and DNA fractions were obtained from concurrent blood and rectal biopsy samples. Phylogenetic trees and resistance profiles showed that the rectal mucosa and the peripheral blood mononuclear cells (PBMCs) harbored different HIV‐1 strains. The resistance‐associated mutations found in each strain corresponded to the treatment history of the patients. The resistance mutations acquired during earlier treatment regimens were detected in the sequences obtained from the rectal samples and in the PBMCs in several of the patients. Also, differences in the resistance profiles were observed between anatomical sites and between RNA and DNA fractions. Thus, a single sample probably will not be representative of the HIV‐1 archived in different sites. Both the resistance profile and phylogeny of HIV‐1 often differed in sequences obtained from RNA and DNA from the same site. These findings suggest that additional information regarding the antiviral resistance profile of the patient might be obtained by testing different anatomical sites. J. Med. Virol. 82: 1103–1109, 2010. © 2010 Wiley‐Liss, Inc.
Detection of SV40 in colon cancer: A molecular case–control study from Northeast Italy
Authors: Campello Cesare , Comar Manola , Zanotta Nunzia , Minicozzi Anna , Rodella Luca , Poli Albino 
Published: May 2010

AbstractTo explore the involvement of the simian polyomavirus SV40 in human colon cancer, a molecular case–control study was undertaken in patients and in their relatives living in an area where the spread of SV40 has already been documented. From 2006 to 2008, 94 colon cancer patients (age: 37–90 years) and 91 subjects (age: 32–70 years) relatives of each index case were enrolled. A blood sample and a specimen of cancer tissue or biopsy were collected, from each patient or control, respectively. Samples were analyzed twice for Polyomavirus (i.e., SV40, JCV, and BKV) by PCR and by quantitative real‐time PCR (RT‐qPCR) with reproducible results. No BKV/JCV was detected either in normal or pathological tissues. SV40 was not present in control subjects, either normal tissue or in biopsies from adenomas or polyps. All blood samples were negative. Conversely, six adenocarcinoma specimens were positive for SV40 sequences (overall prevalence 6.4%, P = 0.03 in comparison with controls). Nevertheless, the SV40‐associated colon cancer risk proved statistically not significant (OR = 3.91; P = 0.115) when adjusted for age. Quantitation of SV40 DNA performed by RT‐qPCR showed a low viral load ranging from 6.2 × 101 to 9 × 103 copies per reaction. This molecular case–control survey showed, for the first time in fresh samples and by RT‐qPCR, that SV40 can be detected in colon cancer tissue. However, the finding was not statistically significant when compared with a well‐structured community control group. Thus, the role of SV40 and other polyomavirus in colon cancer genesis deserves further investigation. J. Med. Virol. 82: 1197–1200, 2010. © 2010 Wiley‐Liss, Inc.
Thermoablation of colorectal liver metastasis
Authors: Kulaylat Mahmoud N. , Gibbs John F. 
Published: May 2010

AbstractThermoablation is a local therapy that is effective in in situ destruction of colorectal liver metastasis while preserving surrounding normal liver tissue. It is less invasive compared to surgery, easy to use, and can be repeated. The therapy provides local control of unresectable disease and is an alternative therapy for small resectable lesions in patients with insufficient hepatic reserve after resection or coexistent comorbid conditions. It can artificially increase the resection margin thus increasing the number of patient candidate for resection. When used in conjunction with liver resection it clears the liver of multiple lesions that are surgically inaccessible or unresectable. Main limitations of the treatment are local recurrence of the disease, treatment‐related complications, and questionable impact on patient. Outcome of therapy can be improved when used as part of multimodality treatment. J. Surg. Oncol. 2010; 101:699‐705. © 2010 Wiley‐Liss, Inc.
Ulcerative colitis and cancer
Authors: Kulaylat Mahmoud N. , Dayton Merril T. 
Published: May 2010

AbstractPatients with ulcerative colitis (UC) are at an increased risk for the development of colorectal cancer (CRC). Unlike sporadic CRC, the cancer in UC patients arises from a focal or multifocal dysplastic mucosa in areas of inflammation. The clinical features of UC‐associated cancer are similar to those found in patients with hereditary non‐polyposis colorectal cancer. As with other varieties of CRC, UC‐associated cancer exhibits a variety of genetic and molecular changes/abnormalities. These abnormalities are however clustered in areas of mucosae with histological abnormalities. The magnitude and timing of these changes are however significantly different. Surveillance and identification of patients at risk for cancer are a challenging problem. J. Surg. Oncol. 2010; 101:706‐712. © 2010 Wiley‐Liss, Inc.
NMR assignment and characterization of proton exchange of the ellagitannin granatin B
Authors: Steinmetz Wayne E. 
Published: May 2010

AbstractGranatin B, a complex ellagitannin extracted from pomegranate fruit, has two equilibrating isomers, form a and form b. A full ensemble of proton and carbon‐13 NMR methods over a wide range of temperature enabled a complete assignment of the more abundant isomer and showed it to be form b. This result is based on the NMR data for granatin alone and agrees with the previous determinations which were based on a combination of chemical methods and a partial assignment of the NMR spectra. The new NMR spectra also yield exchange rates for the hydroxyl protons as a function of temperature. A molecular model involving hydrogen bonding provides an explanation for the exchange data. Copyright © 2010 John Wiley & Sons, Ltd.