bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cave-dwelling bats do not avoid TMT and 2-PT – components of predator odour that induce fear in other small mammals
Authors: Driessens Tess , Siemers Björn M. 
Published: June 2010

SUMMARYRecognition and avoidance of predators is fundamental for the survival of prey animals. Here we conducted the first study assessing chemosensory predator recognition in cave-dwelling bats. We used a Y-maze approach to test the reaction of greater mouse-eared bats (Myotis myotis) to two synthetically derived components of predator odour (2,4,5-trimethyl-3-thiazoline, TMT, a component of fox faeces scent; and 2-propylthietane, 2-PT, a component of mustelid scent) and to the natural scent of the least weasel (Mustela nivalis). It is well documented that rodents and several other small mammals show strong and at least partly innate fear reactions when confronted with these odorants. By contrast, the bats did not show any avoidance or fear reaction, despite the fact that relatively high odorant concentrations were presented. Furthermore, they did not react differently towards predator scent and towards acrid but otherwise neutral odours (basil or goat). The number of entries into in the Y-maze arm with the odour source and the time spent in this arm as well as the bats' overall exploratory activity and several other behavioural variables were not affected by the odour treatments. Generally, the sense of smell is well developed in bats and plays an important role in bat behavioural ecology. It is thus somewhat surprising that the bats did not show any avoidance reaction to predator scent, even though direct contact with a mustelid or fox would result in death. We discuss ecological explanations that might have prevented bats from evolving olfactory predatory recognition and avoidance.
MTERF factors: a multifunction protein family
Authors: Roberti Marina , Polosa Paola Loguercio , Bruni Francesco , Deceglie Stefania , Gadaleta Maria Nicola , Cantatore Palmiro 
Published: June 2010

AbstractThe MTERF family is a large protein family, identified in metazoans and plants, which consists of four subfamilies, MTERF1, 2, 3 and 4. Mitochondrial localisation was predicted for the vast majority of MTERF family members and demonstrated for the characterised MTERF proteins. The main structural feature of MTERF proteins is the presence of a modular architecture, based on repetitions of a 30-residue module, the mTERF motif, containing leucine zipper-like heptads. The MTERF family includes transcription termination factors: human mTERF, sea urchin mtDBP andDrosophilaDmTTF. In addition to terminating transcription, they are involved in transcription initiation and in the control of mtDNA replication. This multiplicity of functions seems to flank differences in the gene organisation of mitochondrial genomes. MTERF2 and MTERF3 play antithetical roles in controlling mitochondrial transcription: that is, mammalian andDrosophilaMTERF3 act as negative regulators, whereas mammalian MTERF2 functions as a positive regulator. Both proteins contact mtDNA in the promoter region, perhaps establishing interactions, either mutual or with other factors. Regulation of MTERF gene expression in human andDrosophiladepends on nuclear transcription factors NRF-2 and DREF, respectively, and proceeds through pathways which appear to discriminate between factors positively or negatively acting in mitochondrial transcription. In this emerging scenario, it appears that MTERF proteins act to coordinate mitochondrial transcription.
What has changed in Hiberno-English: constructions and their role in contact-induced change
Authors: Pietsch Lukas 
Published: June 2010

AbstractThree case studies of contact-induced grammatical innovations in Hiberno-English (Irish English) are presented, with a view to determining a realistic and descriptively adequate syntactic analysis of the mechanisms of syntactic replication under language contact. The case studies deal with a range of different tense-aspect constructions and the morpho-syntax of subordinating clause constructions. It is argued that an approach based on the “construction”, a holistically represented complex form-function mapping as a central cognitive unit of storage and mental representation, offers a plausible and intuitive way of modelling the cross-linguistic identification processes that must be at the heart of what happens in the mind of the bilingual speaker in actuating contact-induced change.
Underuse of Anthracyclines in Women with HER-2+ Advanced Breast Cancer
Authors: Montemurro Filippo , Rossi Valentina , Nolè Franco , Redana Stefania , Donadio Michela , Martinello Rossella , Verri Elena , Valabrega Giorgio , Rocca Maria Cossu , Jacomuzzi Maria Elena , Viale Giuseppe , Sapino Anna , Aglietta Massimo 
Published: June 2010

AbstractAnthracyclines are among the most active drugs in breast cancer. Because of excessive cardiotoxicity, their use in combination with trastuzumab has been discouraged in patients with human epidermal growth factor receptor (HER)-2+ metastatic breast cancer. We sought to describe how this treatment paradigm influenced the use of anthracyclines in this patient setting.We analyzed a multi-institutional database containing the treatment history of 450 patients who received at least one trastuzumab-based regimen for HER-2+ metastatic breast cancer. Patients were considered eligible for anthracyclines for metastatic disease if they were never exposed (NE) or had been previously exposed (PE) to an anthracycline in the neoadjuvant or adjuvant setting and had relapsed after 12 months from the last dose. We then assessed the use of anthracycline-based therapy after failure with the first trastuzumab-based regimen in eligible patients.Three-hundred twenty-one patients were considered eligible for anthracyclines. In total, 190 eligible patients developing disease progression during the initial trastuzumab-based therapy were analyzed. An anthracycline was administered as first salvage treatment in 14 NE and two PE patients. Another 15 NE and nine PE patients received an anthracycline as a further line of therapy. Of 119 eligible patients who died from breast cancer, only 30 received an anthracycline for metastatic disease.In conclusion, despite the fact that two thirds of the patients receiving trastuzumab-based therapy for HER-2 metastatic breast cancer are eligible for anthracyclines, these drugs are infrequently used nowadays to treat trastuzumab-refractory disease. A role for these compounds should be redefined in this patient subset.
Prevention of Biofouling in Industrial RO Systems: Experiences with Peracetic Acid
Authors: van den Broek W.B.P. , Boorsma M.J. , Huiting H. , Dusamos M.G. , van Agtmaal S. 
Published: June 2010

Biofouling is the major fouling type occurring in reverse osmosis (RO) plants treating surface water or effluent from a waste water treatment plant. Severe biofouling can result in operational problems, higher energy and chemical consumption and premature membrane replacement. There are different methods to control biofouling. One method is removal of nutrients in the pre-treatment of the membrane filtration plant, another method is periodic removal of biofouling by chemical cleanings or the use of chemicals to prevent biological growth in the RO systems. In this paper the results of experiments with peracetic acid on three different full scale plants are presented. Two of the plants are operated by Evides Industriewater, the third one by Bètawater, a subsidiary company for industry water of Waterleidingmaatschappij Drenthe (WMD).
One of the main outcomes is that biofouling can be controlled fully on reverse osmosis (RO) plants with the applied method with a peracetic acid based product (Divosan Activ). If the proper measures are taken to avoid oxidation damage due to transition metals, this method with the environmental friendly product results in a stable process and savings by a significantly reduced CIP interval.
Water Balance in a Refinery and Water Reuse Options: Building an Auxiliary Tool for Water Resources Management
Authors: Nogueira D. M. , Mendes C. G. da Nave 
Published: June 2010

The main purpose of this study is to conduct a survey on the detailed Water Balance of Paulínia Refinery, focusing all process units so as to allow its use as data basis for the management of water resources that are consumed there in different forms (natural water, process water, for the fire prevention system, drinkable, demineralized, steam etc,).
The main result shows that 61.5% of the total water collected by the refinery does not reach the effluents treatment station, that is, losses occur during the processes, mainly due to the evaporation in the cooling towers, an intrinsic process factor. Another important identified aspect refers to the relation between equipment maintenance and the consequent water waste. Once these problems are solved, it is estimated that the collection could be reduced by 6.4% and the effluents generation by 16.9%.
Border bases and kernels of homomorphisms and of derivations
Authors: Zieliński Janusz 
Published: June 2010

AbstractBorder bases are an alternative to Gröbner bases. The former have several more desirable properties. In this paper some constructions and operations on border bases are presented. Namely; the case of a restriction of an ideal to a polynomial ring (in a smaller number of variables), the case of the intersection of two ideals, and the case of the kernel of a homomorphism of polynomial rings. These constructions are applied to the ideal of relations and to factorizable derivations.
Validity of Real-Time Ultrasound Imaging to Measure Anterior Hip Muscle Size: A Comparison With Magnetic Resonance Imaging
Authors: Mendis M. Dilani , Wilson Stephen J. , Stanton Warren , Hides Julie A. 
Published: June 2010

Study Design Clinical measurement, criterion standard. Objectives To investigate the validity of real-time ultrasound imaging (USI) to measure individual anterior hip muscle cross-sectional area. Background The hip flexor muscles are important for hip joint function and could be affected by joint pathology or injury. Objectively documenting individual anterior hip muscle size can be useful in identifying muscle size asymmetry and monitoring treatment efficacy for patients with hip problems. USI offers a novel method of measuring individual muscle size in the clinic, but its validity in measuring the anterior hip muscles has not been investigated. Methods Nine healthy participants (5 males, 4 females) underwent imaging of their iliopsoas, sartorius, and rectus femoris muscles with USI and magnetic resonance imaging. Bilateral muscle cross-sectional areas were measured on images from both modalities. Results There was no significant difference (P>.05) in mean cross-sectional area measurements from USI and magnetic resonance imaging for each muscle. Agreement between measurements was high for the iliopsoas (left: intraclass correlation coefficient [ICC3,1] = 0.86; 95% confidence interval [CI]: 0.51, 0.97; right: ICC3,1 = 0.88; 95% CI: 0.57, 0.97), sartorius (left: ICC3,1 = 0.82; 95% CI: 0.41, 0.96; right: ICC3,1 = 0.81; 95% CI: 0.39, 0.95), and rectus femoris (left: ICC3,1 = 0.85; 95% CI: 0.49, 0.96; right: ICC3,1 = 0.89; 95% CI: 0.61, 0.97). Reliability of measuring each muscle with USI was high between 2 trials (ICCs3,1 = 0.84 to 0.94). Conclusions USI is a valid measure of iliopsoas, sartorius, and rectus femoris muscle size in healthy people, as long as a strict measurement protocol is followed. J Orthop Sports Phys Ther 2010;40(9):577–581.doi:10.2519/jospt.2010.3286
Prognostic factors for the incidence and recovery of delayed facial nerve palsy after vestibular schwannoma resection
Authors: Morton Ryan P. , Ackerman Paul D. , Pisansky Marc T. , Krezalek Monika , Leonetti John P. , Raffin Michael J.M. , Anderson Douglas E. 
Published: June 2010

Object
Preservation of facial nerve function in vestibular schwannoma (VS) resections remains a significant operative challenge. Delayed facial palsy (DFP) is one specific challenge yet to be fully elucidated. The aim of this study was to evaluate DFP among VS resection cases to identify significant prognostic factors associated with its incidence and clinical recovery.

Methods
This investigation involves a retrospective review of 104 cases of VS resection that occurred between December 2005 and May 2007. Patients who developed DFP were compared with patients exhibiting no facial palsy postoperatively with regard to surgical approach, severity and day of palsy onset, tumor size, intraoperative facial nerve monitoring, and postoperative recovery and treatment. Patients who demonstrated immediate facial palsy (IFP) following VS resection were also analyzed. Furthermore, specific analyses were performed in 2 distinct DFP patient groups: those who developed DFP after postoperative Day 3 (“late onset DFP”), and those whose palsy worsened after initial DFP identification (“deteriorators”).

Results
Of the 104 patients who underwent VS resection, 25.0% developed DFP and 8.6% demonstrated IFP postoperatively. The DFP group did not differ significantly in any measure when compared with patients with no postoperative facial palsy. However, patients with DFP presented with significantly smaller tumor sizes than patients with IFP. This IFP group averaged significantly smaller intraoperative facial nerve responses than patients without facial palsy, and larger tumor sizes than both the DFP and no facial palsy groups. Within the DFP group, patients with late onset DFP showed diminished intraoperative facial nerve responses when compared with the total DFP patient population. In total, 25 (96.2%) of 26 patients with DFP and 7 (77.8%) of 9 patients with IFP recovered to normal or near-normal facial function (House-Brackmann Grade I or II) at longest clinical follow-up.

Conclusions
Although patients with DFP did not exhibit any distinguishable characteristics when compared with patients without postoperative facial palsy, our analysis identified significant differences in patients with palsy presenting immediately postoperatively. Further study of patients with DFP should be undertaken to predict its incidence following VS resection.
Une gestion de l'apprentissage de la chimie expérimentale en premier cycle universitaire
Authors: Pernot Christiane 
Published: June 2010

The work presented here concerns a reasoned implementation of semester-units in experimental chemistry during the first college year (Université Paris Sud). In these units both learning and assessment go through a definition of the function and of the content of experimental chemistry as a subject matter.
After a critical analysis of usual practices, choices have been made in order to modify teaching and decisions have been taken so that these choices are respected (content, number of hours, pedagogical strategy, rating...).
The first semester unit, entirely independent of the theoretical course, will be presented.
Des représentations spatiales de concepts : pour quoi faire ?
Authors: de Bueger-Van der Borght Cécile , Lambert Joëlle 
Published: June 2010

In this article two different tools for the spatial representation of concepts are presented : the concept map and the terminological network. The objectives of these tools and the steps taken for their construction are explained. The advantages and limitations of each of them are discussed as well as their complementary characteristics.
The concept map focuses on the logic of the discipline being taught during didactic discourse. The terminological network enables to visualise the actual linkages formed by the teacher among the different terms, their density and the meaning they are given.
Conceptions des opérateurs de bas niveau de qualification du secteur agro-alimentaire en matière de micro-organismes. Incidences sur la formation professionnelle à l'hygiène et à la qualité des produits
Authors: Bazile Joëlle 
Published: June 2010

The concept of the micro-organism is vital for training in hygiene and for the microbiological quality of products. Unskilled workers, for whom this kind of training course is intended, already have their own conceptions of the word “germ” which they use freely at their place of work as well as in their social life.
We have carried out an exploratory study aiming to pinpoint these different conceptions. An analysis of interviews with workers in the meat industry has enabled us to bring to light a certain number of obstacles which we believe should be taken into account in the training.
La formation professionnelle agricole. Tendances et perspectives
Authors: Méaille Michel , Marshall Éric 
Published: June 2010

Cet article résulte d’un entretien avec deux responsables de l’enseignement technique agricole associés à la recherche pédagogique. Il fait le point sur les tendances et les perspectives de cet enseignement, après dix années de rénovation pédagogique, et face au nouveau défi que représente l’évolution du secteur professionnel agricole, dans le contexte de la nouvelle politique agricole européenne.
Les auteurs rappellent les acquis de cette rénovation, en particulier la pluridisciplinarité et la pédagogie de l’action, et précisent les particularités de l’enseignement technique agricole, principalement dans les supports
Développement de la compétence à résoudre des problèmes sur les nouvelles technologies de l'automobile
Authors: Vachon Jean-Claude , Fortin Marc 
Published: June 2010

El grupo IST (Integración de Ciencias y Técnicas), compuesto por investigadores de la Universidad del Québec en Chicoutimi, tiene como objetivo el perfeccionamiento de métodos didácticos destinados al desarrollo de la capacidad de solución de problemas técnicos en mecánica de automóviles.
Este artículo relata los trabajos realizados por el grupo. Después de analizar la situación actual se precisan las componentes cognoscitivas que fundamentan los instrumentes didácticos, los cuales son brevemente descritos. El artículo se termina con la descripción de una estrategia para la aplicación de estos intrumentos.
Un instrument pour évaluer un état conceptuel : exemple du concept de couleur
Authors: Chauvet Françoise 
Published: June 2010

Este artículo describe el procedimiento de construcción de un instrumento de evaluación de las concepciones y de los modos de razonamientos de los estudiantes sobre el tema del color. El estudio previo de las ideas comunes y la observación de las reacciones de los estudiantes en el curso de la experimentación de una secuencia de enseñanza, permitió despejar un número limitado de indicadores (parejas «pregunta/elemento de respuesta») relativos a la comprensión de los aspectos múltiples del color (físicos, técnicos, perceptivos).
Para darune visión más global del estado de los conocimientosy de las herramientas conceptuales disponibles, las parejas fueron reagrupadas en familias caracterfsticas de un tipo de comprensión. La repartición de las tasas de ocurrencia de las parejas en una población dada marca el perfil conceptual de este grupo.
Questions posées par la conception et la réalisation d'un environnement d'aide à la résolution de problèmes en chimie
Authors: Schwob Monique , Blondel François-Marie 
Published: June 2010

La realización de un programa informático educativo supone la implementación de conocimientos relativos a varios dominios : la informática, y particularmente la representación de conocimientos y las interfases hombre-máquina, la didáctica, la psicología cognitiva, las ciencias de la educacion, porno citarque las principales.
En la ocasión de un projecto que trata sobre la resolución deproblemas en química, la concepción y realización de un medio de aprendizaje interactivo, llevó ante todo a la proposición de algunas preguntas, conocidas por la mayoría, pero vistas bajo un ángulo diferente. En este texto, presentamos algunas de esas preguntas, en la frontera entre la didactica y la psicología cognitiva del trabajo, así como algunas de las respuestas posibles : ¿Cuál espacio de conocimientos para el problema de química ? ¿ Cuál es la naturaleza de la complejidad de este problema para los alumnos ? c Qué lenguaje permite representar el sistema físico-químico asociado a una reacción ? ¿ Cómo representar el aspecto temporal y dinámico de la reacción ?
Conceptions d'élèves et d'étudiants français et tunisiens sur la conduction dans les piles électrochimiques / Conceptions of French and Tunisian students on conduction in electrochemical cells
Authors: Bouraoui Kamel , Maurines Laurence 
Published: June 2010

Cet article présente les conceptions sur la conduction électrique dans les piles électrochimiques repérées chez des élèves et des étudiants français ou tunisiens. Cinquante-cinq lycéens (de 16-17 ans) et soixante-quatre étudiants ont participé à cette étude. La démarche mise en place associe un questionnaire et des entretiens semi-directifs basés sur l’observation de dispositifs expérimentaux.
L’omniprésence des conceptions relatives à la présence des électrons en solution est essentiellement due à l’assimilation du courant électrique à un déplacement d’électrons, même dans les électrolytes. L’absence de liaison entre le mouvement des ions et le courant électrique constitue un obstacle à la construction des concepts nécessaires à la compréhension du fonctionnement des piles électrochimiques. Quelques facteurs de persistance des conceptions repérées sont brièvement analysés.
Étude croisée du darwinisme en classe de première littéraire (SVT et histoire). Compte rendu d'innovation / Cross-studies of the darwinism in premiere I (biology and history). Report of innovation
Authors: Chanet Bruno , Cottour Thierry 
Published: June 2010

Estudio cruzado del darwinismo en clase de segundo de bachillerato literario francés (biología e historia). Informe de innovación
El objetivo de este artículo es presentar una actividad llevada a cabo en clase de segundo de bachillerato (première littéraire). Un análisis conjunto de documentales científicos e histôricos permitió entender no sólo las características y el origen del Darwinismo sino también revelar la influencia sobre los movimientos sociopolíticos de los siglos XIX y XX. Este estudio ha demostrado el interés de las interacciones entre las asignaturas.
Nouveaux dispositifs d'enseignement au lycée. Nouveaux processus d'apprentissage de l'élève ; nouvelles pratiques de l'enseignant / New teaching devices in high school. Students' new learning processes; teachers' new teaching practices
Authors: Crindal Alain , Larcher Claudine 
Published: June 2010

Neue Unterrichtsverfahren am Lycée. Neue Lernverfahren fiir den Schüler, neue Lernpraktiken .
Dieser Artikel berichtet über die Unterrichtsverfahren, die in den letzten Jahren in die französischen Curricula der allgemeinbildenden und berufli- chen Schulen eingeführt wurden, TPE : Travaux personnels encadrés (persönliche Arbeiten unter Lehrerbegleitung) und PPCP : Projet pluridisciplinaire à caractère professionnel (fachübergreifendes Projekt mit beruflichem Charakter). Bei diesen Verfahren haben wir zum einen den intellektuellen Prozess bei der Strukturierung der Kenntnisse analysiert, zum anderen die neuen Praktiken der Lehrer, um den Schüler in diesen Vorgang zu führen. Dazu haben wir mehrere Stufen bei der Strukturierung unterschieden und haben an Hand einiger Beispiele die Entwicklung der Schüler gezeigt. Wir haben auch „Haltungen“ erkannt, mit denen die Lehrer ihre neue Rolle entwerfen