bluuebunny/crossref_metadata_2025_split huggingface dataset:
CropMetabolome: a comprehensive metabolome database for major crops cross eight categories
Authors: Shi Han , Zhu Yan , Wu Xueting , Jiang Tao , Li Xuetong , Liu Jianju , Di Ye , Chen Feng , Gao Jinshan , Xu Xiaoyan , Xiao Ning , Feng Xianzhong , Zhang Peng , Wu Yongrui , La Qiong , Li Aihong , Chen Ping , Li Xuan 
Published: May 2024

SUMMARYChemical compositions of crops are of great agronomical importance, as crops serve as resources for nutrition, energy, and medicines for human and livestock. For crop metabolomics research, the lack of crop reference metabolome and high‐quality reference compound mass spectra, as well as utilities for metabolic profiling, has hindered the discovery and functional study of phytochemicals in crops. To meet these challenging needs, we have developed the Crop Metabolome database (abbreviated as CropMetabolome) that is dedicated to the construction of crop reference metabolome, repository, and dissemination of crop metabolomic data, and profiling and analytic tools for metabolomics research. CropMetabolome contains a metabolomics database for more than 50 crops (belonging to eight categories) that integrated self‐generated raw mass spectral data and public‐source datasets. The reference metabolome for 59 crop species was constructed, which have functions that parallel those of reference genome in genomic studies. CropMetabolome also contains ‘Standard compound mass spectral library’, ‘Flavonoids library’, ‘Pesticide library’, and a set of related analytical tools that enable metabolic profiling based on a reference metabolome (CropRefMetaBlast), annotation and identification of new metabolites (CompoundLibBlast), deducing the structure of novel flavonoid derivatives (FlavoDiscover), and detecting possible residual pesticides in crop samples (PesticiDiscover). In addition, CropMetabolome is a repository to share and disseminate metabolomics data and a platform to promote collaborations to develop reference metabolome for more crop species. CropMetabolome is a comprehensive platform that offers important functions in crop metabolomics research and contributes to improve crop breeding, nutrition, and safety. CropMetabolome is freely available at https://www.cropmetabolome.com/.
Marchenko–Pastur Law for Spectra of Random Weighted
Bipartite Graphs
Authors: Nadutkina A. V. , Tikhomirov A. N. , Timushev D. A. 
Published: May 2024

Abstract
We study the spectra of random weighted bipartite graphs. We establish that, under
specific assumptions on the edge probabilities, the symmetrized empirical spectral distribution
function of the graph’s adjacency matrix converges to the symmetrized Marchenko-Pastur
distribution function.
Relationship between parathyroid adenoma size, weight and histological subtypes with perioperative serum levels
Authors: Chuang Fred , Ng Shu Kay , Khan Roger , Lam Alfred King-yin 
Published: May 2024

AimsThis study aims to identify associations between parathyroid adenoma (PTA) characteristics (histology, weight and size) with the change in parathyroid hormone (PTH) and calcium levels.MethodsA historical cohort study was conducted on adult patients with solitary PTA removed in the Gold Coast Health Precinct, Australia, between 2017 and 2022.ResultsPTA weight is correlated with the change in day 1 PTH level (r=0.26, p=0.036), the change in day 1 corrected calcium level (r=0.20, p=0.033), and the change in follow-up corrected calcium level (r=0.47, p<0.001). The largest dimension (size) of PTA is also correlated with the change in day 1 PTH (r=0.30, p=0.011) and the change in follow-up corrected calcium level (r=0.40, p<0.001). Adjusted for age and gender, a statistically significant negative correlation was found between day 1 PTH level and adenoma size, resulting in a 0.5% change in size for every percentage change in PTH level (equating to a 5.0% increase in variance explained, p=0.038). Similarly, a negative correlation was identified in day 1 corrected calcium levels and weight, with a 4.7% change in weight for every percentage of change in day 1 corrected calcium level (an increase of 5.6% variance explained, p=0.010). In addition, a negative correlation was identified, where every 3.1% change in size (an increase of 17.4% variance explained, p<0.001) and 7.6% change in weight (an increase of 22.7% variance explained, p<0.001) was seen with every percentage change in follow-up corrected calcium levels. Clear-cell PTA had the most significant percentage fall in day 1 corrected calcium levels compared with other PTA subtypes (p=0.007).ConclusionsPreoperative calcium and PTH levels correlate with PTA weight and size. The degree of change in postoperative corrected calcium levels behaved differently in the clear-cell subtype.
Complete nanopore repeat sequencing of SCA27B (GAA-FGF14ataxia) in Japanese
Authors: Miyatake Satoko , Doi Hiroshi , Yaguchi Hiroaki , Koshimizu Eriko , Kihara Naoki , Matsubara Tomoyasu , Mori Yasuko , Kunieda Kenjiro , Shimizu Yusaku , Toyota Tomoko , Shirai Shinichi , Matsushima Masaaki , Okubo Masaki , Wada Taishi , Kunii Misako , Johkura Ken , Miyamoto Ryosuke , Osaki Yusuke , Miyama Takabumi , Satoh Mai , Fujita Atsushi , Uchiyama Yuri , Tsuchida Naomi , Misawa Kazuharu , Hamanaka Kohei , Hamanoue Haruka , Mizuguchi Takeshi , Morino Hiroyuki , Izumi Yuishin , Shimohata Takayoshi , Yoshida Kunihiro , Adachi Hiroaki , Tanaka Fumiaki , Yabe Ichiro , Matsumoto Naomichi 
Published: May 2024

BackgroundAlthough pure GAA expansion is considered pathogenic in SCA27B, non-GAA repeat motif is mostly mixed into longer repeat sequences. This study aimed to unravel the complete sequencing ofFGF14repeat expansion to elucidate its repeat motifs and pathogenicity.MethodsWe screenedFGF14repeat expansion in a Japanese cohort of 460 molecularly undiagnosed adult-onset cerebellar ataxia patients and 1022 controls, together with 92 non-Japanese controls, and performed nanopore sequencing ofFGF14repeat expansion.ResultsIn the Japanese population, the GCA motif was predominantly observed as the non-GAA motif, whereas the GGA motif was frequently detected in non-Japanese controls. The 5′-common flanking variant was observed in all Japanese GAA repeat alleles within normal length, demonstrating its meiotic stability against repeat expansion. In both patients and controls, pure GAA repeat was up to 400 units in length, whereas non-pathogenic GAA-GCA repeat was larger, up to 900 units, but they evolved from different haplotypes, as rs534066520, located just upstream of the repeat sequence, completely discriminated them. Both (GAA)≥250and (GAA)≥200were enriched in patients, whereas (GAA-GCA)≥200was similarly observed in patients and controls, suggesting the pathogenic threshold of (GAA)≥200for cerebellar ataxia. We identified 14 patients with SCA27B (3.0%), but their single-nucleotide polymorphism genotype indicated different founder alleles between Japanese and Caucasians. The low prevalence of SCA27B in Japanese may be due to the lower allele frequency of (GAA)≥250in the Japanese population than in Caucasians (0.15% vs 0.32%–1.26%).ConclusionsFGF14repeat expansion has unique features of pathogenicity and allelic origin, as revealed by a single ethnic study.
#Headlesspreggos: challenging visual imaginaries of pregnancy and reproduction
Authors: Cattapan Alana , Mastromatteo Danielle 
Published: May 2024

Amid new abortion restrictions in the USA, scientific advances in genetic technologies and investigations of COVID-19 vaccinations in pregnancy, news stories about reproduction abound, often accompanied by images of what journalist Josie Glausiusz has called the “headless, legless, pregnancy bump”. These images of disembodied pregnant torsos at once improve search engine optimisation for news organisations while perpetuating the view of the ‘bump’ as the quintessential visual representation of pregnancy.The images that accompany news articles convey meaning beyond what is included in the text and work to reinforce stereotypes about race, gender and age. In the so-called obesity epidemic, for example, psychotherapist and fat activist Charlotte Cooper documented how images of fat people with their heads cropped out view had become a visual symbol of abjection—‘the headless fatty’—without a face or agency to speak of. The use of ‘headless preggos’ similarly divorces pregnant people from the embodied experience of their pregnancies, reducing them to a single body part.In this article, we chronicle our experiences tracking images of headless preggos via Twitter, arguing that their use works to erase pregnant people’s autonomy and to construct the fetus as the central concern in reproductive interventions. We begin by tracing the evolution of visual representations of pregnancy including the increasing focus on the fetus and ‘bump’. We then provide a description of our experience with the Twitter account, including our exchanges with academics, journalists and others that highlight how the continued reliance on headless preggos obscures the experiences of pregnant people by focusing all attention on the fetus, as well as how the same images might be thoughtfully deployed. We conclude by offering suggestions for those creating and selecting images that might result in more robust, creative visual representations of pregnancy and reproduction.
Uncomplicated epidural removal in a patient on a therapeutic heparin infusion: a case report
Authors: Hu Lizbeth , Adegboye Janet , Chang Angela Tung , Hanna Marie , Jaremko Kellie 
Published: May 2024

BackgroundUnanticipated postoperative thrombotic complications can occur in complex patients who receive preoperative epidurals. Therefore, it is imperative that we consider the risks and benefits of epidural management in the setting of therapeutic anticoagulation. We present a case of epidural catheter removal on a heparin infusion, due to the extreme risk of holding anticoagulation for any duration.Case reportA woman with hilar cholangiocarcinoma presented after uncomplicated hepatectomy, bile duct resection and hepaticojejunostomy, with a thoracic epidural for analgesia. On postoperative day 1, she developed a total portal vein thrombosis, requiring emergent open thrombectomy, transhepatic stenting and high-dose heparin infusion while the epidural was indwelling. The patient was deemed to have a profound risk of re-thrombosis if heparin were paused. Therefore, a multidisciplinary discussion between hepatobiliary surgery, critical care, neurosurgery, haematology, acute pain service and the patient’s family ensued regarding epidural management. Options included catheter-directed thrombolytics to her stent while holding systemic anticoagulation, sterilely leaving the epidural catheter in place indefinitely, injecting prothrombotic agent into the epidural prior to removal, or removing the catheter without holding anticoagulation. Due to the risk of re-thrombosis in the portal vein and liver infarction, the heparin infusion was decreased to achieve the lowest therapeutic anti-Xa level, and the epidural was removed. The patient was continuously monitored in the intensive care unit without any adverse events.ConclusionA multidisciplinary discussion is paramount to weigh the risk of epidural haematoma if a catheter is removed on therapeutic anticoagulation against catastrophic thrombosis if anticoagulation is paused.
Exploring the molecular interactions of dorzolamide hydrochloride in aqueous solutions: a comprehensive study using thermophysical techniques and molecular simulations across various temperatures
Authors: Rayinuthala Yesupadamu , Medepalli David Raju , Munnangi Srinivasa Reddy , Nayeem Sk Md , Ravulapalli Lakshmi Tulasi 
Published: May 2024

This research begins with the initial assessment of key physical properties—density ( ρ), speed of sound ( u), and refractive index ( nD ) in binary aqueous solutions of dorzolamide hydrochloride. These properties were measured in solutions with varying molalities, ranging from 0.0 to 0.0276, under standard atmospheric conditions and at temperatures between 300.15 and 320.15 K. From these measurements, we were able to calculate a range of important parameters, including the apparent molar volume ( Vϕ), its limiting values ([Formula: see text]), limiting apparent molar expansivity ([Formula: see text]), Helper’s constant ([Formula: see text]), apparent molar isentropic compression ( κϕ), and its limiting values ([Formula: see text]), specific refraction ( RD), molar refraction ( RM), and hydration number ( nh). These calculated values provided insights into the strong interactions between the solute and solvent in the liquid system. They also shed light on the presence of various molecular interactions, such as inter- and intramolecular hydrogen bonds, dipole–dipole, and dipole-induced-dipole interactions, as well as the ability of the solute to influence the structure of the surrounding water molecules. Additionally, we derived the densities of dorzolamide hydrochloride solutions from molecular dynamics (MD) simulations, which showed a strong correlation with our experimental findings, underscoring the reliability of MD simulations in such studies. In the end, our combined study on dorzolamide hydrochloride in water demonstrates that it shapes structures because it has lower volumetric properties and stronger hydrogen bonds in MD simulations. More alchemical free energy calculations show that there are big changes in solvation energies. This is important for understanding how dorzolamide hydrochloride works in water.
Nano Zinc Oxide Particle Synthesis from Bio-Waste Selaginella willdenowii Leaf Extract: A Multi-Faceted Approach for Environmental and Biomedical Applications
Authors: Sudheesh Arjun K. , Alwin George C. , Joseph Kadanthottu Sebastian , Jaison Juhi Puthukulangara , Jose Joel 
Published: May 2024

Selaginella willdenowii, a commonly used greenhouse fern, was often used as a biowaste to synthesize zinc oxide nanoparticles (ZnO NPs) in an eco-friendly and cost-effective way. UV–Visible spectra studies were carried out to confirm the synthesis of S. willdenowii-mediated ZnO NPs (SW-ZnO NPs), and a peak at 367[Formula: see text]nm with a sharp band gap of 3.415[Formula: see text]eV was observed. The X-ray diffraction analysis indicated that the crystalline size of the synthesized SW-ZnO NPs was 11.971[Formula: see text]nm. The phytochemicals present in the extracts and the compounds involved in the reduction of metal to nanoparticles were determined by Fourier Transform Infrared analysis. Scanning electron microscopy was utilized to analyze the surface morphology and size of the obtained SW-ZnO NPs. The examination revealed that they exhibited a hexagonal shape, with an average size falling within the range of 17–23[Formula: see text]nm. Under ultra-violet light, reactive blue 220 and reactive yellow 145 dyes showed 78.06% and 60.14% degradation, showing potential photocatalytic degradation activity. The synthesized SW-ZnO NPs also exhibited antimicrobial activity against bacterial strains (Escherichia coli and Bacillus subtilis) and fungal cultures (Candida tropicalis and Candida albicans) showed cytotoxic activity against Hep-G2 cell lines. Our results suggest the green synthesized SW-ZnO NPs have potential photocatalytic, antimicrobial and cytotoxic potential.
Impacto de uma pesquisa-ação nos indicadores vacinais em Minas Gerais
Authors: Souza Janaina Fonseca Almeida , Silva Thales Philipe Rodrigues da , Oliveira Thais Moreira , Vimieiro Aline Mendes , Teixeira Antônia Maria da Silva , Soares Adriana Coelho , Ribeiro Elice Eliane Nobre , Freitas Giselle Lima de , Gaspar Eduarda Dantas , Matozinhos Fernanda Penido 
Published: May 2024

Esta errata corrige o artigo: https://doi.org/10.11606/s1518-8787.2024058005484
Hypertension Prevalence and Related Risk Factors Among Mexican American Adults Are Increasing: National Health and Nutrition Examination Survey 1999 to 2018
Authors: Briggs Early Kathaleen , Valencia Sandra I. , Stendell‐Hollis Nicole , Klyve Dominic , Gee David L. 
Published: May 2024

Background
Acculturation affects hypertension prevalence among Hispanic people, but there have been no recent analyses specifically focused on Mexican American (MA) people. We sought to determine age‐adjusted hypertension prevalence, abdominal obesity, and acculturation trends among MA adults and non‐Hispanic White adults.

Methods and Results

Data from the NHANES (National Health and Nutrition Examination Survey) were analyzed in 2‐year increments to observe trends in hypertension and risk factors (age, sex, body mass index, smoking status, abdominal obesity, waist‐to‐height ratio (WHtR), education, and income). Acculturation was based on three commonly used measures. The sample included 30 920 adults. Age‐adjusted hypertension prevalence is higher in MA adults (52.7%) than White adults (48.3%). Hypertension risk factors—age, obesity prevalence, WHtR, acculturation—all significantly increased among MA adults, while smoking declined. Higher acculturation scores increased hypertension likelihood (odds ratio [OR], 1.44 [95% CI, 0.91–1.97]) for MA adults compared with those with lower acculturation scores. White adults with elevated WHtR >0.5 had a 40% higher risk of hypertension than those with WHtR <0.5, but among MA adults, elevated WHtR did
not
increase risk for hypertension. There was a significant
increase
in hypertension prevalence among MA adults from 2003 to 2018 at an average biennial rate of 2.23%. There was no change in hypertension prevalence among White adults from 1999 to 2018.

Conclusions
Over 20 years of NHANES, more highly acculturated MA adults were at greater risk for hypertension, despite declines in smoking and controlling for age, sex, obesity status, education, and income. Finding ways to promote more traditional lifestyle and eating habits for MA adults could be a beneficial approach to reducing hypertension risk factors in this population.
Safety and Efficacy of the Bimodal Armadillo Catheter for Intracranial Interventions via the Transfemoral Approach
Authors: Katz Jeffrey M. , Khawar Haroon , Huang Brendan , Chulpayev Boris , Jung Richard 
Published: May 2024

BACKGROUNDThe Armadillo (Q'Apel Medical Inc., Fremont, CA) is a novel bimodal guide catheter, combining properties of a long support sheath with a large‐bore distal access catheter, whose stiffness can be adjusted from “track” mode during navigation to “support” mode for intervention. The main objective of this study was to determine the safety and efficacy of the Armadillo for intracranial interventions via the transfemoral approach.METHODSThis is a retrospective study of our initial Armadillo experience, composed of all patients who underwent an intracranial intervention using the Armadillo via the transfemoral route, between December 2022 and December 2023, at a single institution. Transvenous, external carotid, and stroke‐related interventions were excluded.RESULTSOf 62 total interventions with the Armadillo catheter, 58 procedures (53/58 [91.4%] for aneurysms, 3/58 [5.6%] for arteriovenous malformations, and 2/58 [3.4%] for intracranial stenosis) in 55 patients (mean age, 57.2 [standrad deviation (SD), 12.4] years; 46/55 [83.6%] female sex) met study criteria. Most interventions were in the anterior circulation (51/58 [87.9%]) and significant carotid or vertebral artery tortuosity was encountered in 10 of 58 (17.2%) cases. The Armadillo was the primary sheath in 57/58 (98.3%) cases, and 50/58 (86.2%) received vasodilator for vasospasm prophylaxis prior to distal navigation. The Armadillo was successfully navigated to the intended target location in 52 of 58 (89.7%) procedures, predominantly over a macro‐guidewire alone (41/58 [70.7%]). The need for a triaxial system during the intervention was obviated in 36 of 58 (62.1%) procedures, and all interventions were completed successfully without having to exchange for an alternate support catheter. There were no Armadillo‐related complications.CONCLUSIONThe Armadillo was highly effective as a long guide sheath for intracranial interventions via the transfemoral route, with a high rate of successful distal navigation and no device‐related complications.
What Is a Visual Stream?
Authors: Ritchie J. Brendan , Montesinos Sebastian , Carter Maleah J. 
Published: May 2024

Abstract
The dual stream model of the human and non-human primate visual systems remains Leslie Ungerleider's (1946–2020) most indelible contribution to visual neuroscience. In this model, a dorsal “where” stream specialized for visuospatial representation extends through occipitoparietal cortex, whereas a ventral “what” stream specialized for representing object qualities extends through occipitotemporal cortex. Over time, this model underwent a number of revisions and expansions. In one of her last scientific contributions, Leslie proposed a third visual stream specialized for representing dynamic signals related to social perception. This alteration invites the question: What is a visual stream, and how are different visual streams individuated? In this article, we first consider and reject a simple answer to this question based on a common idealizing visualization of the model, which conflicts with the complexities of the visual system that the model was intended to capture. Next, we propose a taxonomic answer that takes inspiration from the philosophy of science and Leslie's body of work, which distinguishes between neural mechanisms, pathways, and streams. In this taxonomy, visual streams are superordinate to pathways and mechanisms and provide individuation conditions for determining whether collections of cortical connections delineate different visual streams. Given this characterization, we suggest that the proposed third visual stream does not yet meet these conditions, although the tripartite model still suggests important revisions to how we think about the organization of the human and non-human primate visual systems.
A Phenomenological Investigation of the Experiential Features of Trauma
Authors: Hovila Tiia-Mari 
Published: May 2024

Abstract
This article examines the experience of trauma, paying particular attention to how traumatization affects one’s sense of body, time, and intersubjectivity. Furthermore, this study provides one example of how literature can be used in phenomenological research. Using both classical and contemporary phenomenological sources and deepening the analysis by discussing a first-person description by Marguerite Duras, the article aims to clarify one crucial aspect of traumatic experience: trauma alters experiential features so that the relation between traumatic past and present becomes rigid.