bluuebunny/crossref_metadata_2025_split huggingface dataset:
Have you made up your story? The effect of suspicion and liars' strategies on reality monitoring
Authors: Gnisci Augusto , Caso Letizia , Vrij Aldert 
Published: May 2009

AbstractThe impact of Veracity, Suspicion (weak or strong) and Strategy (making up a story or using past experiences) on Reality Monitoring (RM) scores was examined. A total of 158 undergraduate students were interviewed twice about the possession of an object. In one interview they were asked to lie, and in the other to tell the truth (Veracity factor). In both conditions, suspicion was raised in the second half of the interview: Participants were accused of lying by the interviewer and asked to repeat their account (Raised Suspicion factor). At the end of the interview participants were asked whether their lies were totally made up or whether they described an event that they had experienced previously (Strategy factor). Results revealed that truth tellers and liars' speech differed from each other in accordance with RM theory, even when the interviewer was suspicious and even when liars fabricated a story by describing events that they had previously experienced. Copyright © 2009 John Wiley & Sons, Ltd.
Congenital skin pedicles with or without amniotic band sequence: Extending the human phenotype resembling mouse disorganization
Authors: Isidor B. , Baujat G. , Le Caignec C. , Pichon O. , Martin‐Coignard D. , Toutain A. , David A. 
Published: May 2009

AbstractCongenital skin pedicles are very rare and usually described in association with multiple congenital anomalies. Here, we report on six patients with congenital pedicle skin hamartomatous lesions. Two patients showed a single skin pedicle lesion, one of whom was also shown to have 22q11.2 microdeletion syndrome, and four patients also had severe limb anomalies for which they were originally diagnosed with amniotic band sequence (ABS). We propose that all these infants instead show various forms of the phenotype resembling disorganization in the mouse. This article supports previous reports suggesting that “Disorganization‐like” mutations may cause cases with apparent ABS. Owing to these reports, we propose the hypothesis that hamartomatous skin pedicles and “ABS plus” are different phenotypes of the human disorder resembling disorganization. © 2009 Wiley‐Liss, Inc.
Unstable familial transmissions of Huntington disease alleles with 27–35 CAG repeats (intermediate alleles)
Authors: Semaka A. , Collins J.A. , Hayden M.R. 
Published: May 2009

AbstractThere are inconsistent reports regarding the likelihood of repeat instability for alleles with 27–35 CAG repeats in the Huntington disease (HD) gene. We have examined the intergenerational stability of such intermediate alleles in 51 families from the University of British Columbia's DNA and Tissue Bank for Huntington Disease Research (UBC‐HD Databank). A total of 181 transmissions were identified, with 30% (n = 54/181) of the alleles being unstable upon transmission. The unstable transmissions included both expansions (n = 37) and contractions (n = 17) of CAG size. Of the expanded alleles, 68% (n = 25/37) expanded into the HD range (>36 CAG). Therefore, 14% (n = 25/181) of the 27–35 CAG allele transmissions examined expanded into the disease‐associated range resulting in a new mutation for HD. Significantly, of these new mutations, 40% (n = 10/25) originated from an allele with 35 CAG repeats with CAG repeat expansions ranging from +1 CAG to +23 CAG. The proportion of new mutations in the UBC‐HD Databank is consistent with the most recent new mutation rate for HD, estimated to be at least 10%. The observed difference in the stability of HD intermediate allele transmissions in this data set and in other studies may be a reflection of a small sample size. Alternately, these inconsistencies may indicate an underlying difference in genetic factors which influence repeat instability between the different populations examined. Additional studies determining the frequency and magnitude of repeat instability in this CAG repeat range and factors that influence instability are urgently needed. Until we understand the clinical implications of HD alleles with 27–35 CAG repeats and establish reliable risks of instability, we should exercise caution when translating these results to the clinic. © 2009 Wiley‐Liss, Inc.
Association study of the serotoninergic system in migraine in the spanish population
Authors: Corominas R. , Sobrido M.J. , Ribasés M. , Cuenca‐León E. , Blanco‐Arias P. , Narberhaus B. , Roig M. , Leira R. , López‐González J. , Macaya A. , Cormand B. 
Published: May 2009

AbstractIn order to evaluate the contribution of 19 serotonin‐related genes to the susceptibility to migraine in a Spanish population we performed a case–control association study of 122 single nucleotide polymorphisms (SNPs), selected according to genetic coverage parameters, in 528 migraine patients —308 with migraine without aura (MO) and 220 with migraine with aura (MA)— and 528 sex‐matched migraine‐free controls. The single‐marker analysis identified nominal associations with the migraine phenotype or with the MO or MA subtypes. The multiple‐marker analysis revealed risk haplotypes in three genes that remained significantly associated with migraine after correction by permutations. Two‐marker risk haplotypes were identified in the HTR2B (rs16827801T‐rs10194776G) and MAOA (rs3027400G‐rs2072743C) genes conferring susceptibility to MO, and a four‐marker haplotype in DDC was specific of MA (rs2329340A‐rs11974297C‐rs2044859T‐rs11761683G). The present study supports the involvement of HTR2B and MAOA genes in the genetic predisposition to MO, while DDC might confer susceptibility to MA. These results suggest a differential involvement of serotonin‐related genes in the genetic background of MO and MA. © 2009 Wiley‐Liss, Inc.
Epileptic encephalopathy in a girl with an interstitial deletion of Xp22 comprising promoter and exon 1 of the CDKL5 gene
Authors: Bahi‐Buisson Nadia , Girard Benoit , Gautier Agnes , Nectoux Juliette , Fichou Yann , Saillour Yoann , Poirier Karine , Chelly Jamel , Bienvenu Thierry 
Published: May 2009

AbstractWe report a 2‐year‐old girl with early onset seizures variant of Rett syndrome with a deletion at Xp22 detected by multiplex ligation‐dependent probe amplification (MLPA) technique. This patient presented with tonic seizures at 7 days of life. Subsequently, she developed infantile spasms at three months and finally refractory myoclonic epilepsy. She demonstrated severe encephalopathy with hypotonia, deceleration of head growth, with eye gaze but limited eye pursuit, no language, limited hand use, and intermittent hand stereotypies. This combination of clinical features, suggestive of early onset variant of Rett syndrome led us to screen the CDKL5 gene. In a first step, screening of the whole coding sequence of the CDKL5 gene revealed no point mutations. In a second step, we searched gross rearrangements by MLPA and identified a microdeletion affecting both the promoter and exon 1 in CDKL5. Subsequent analysis on a Nimblegen HD2 microarray confirmed a deletion of approximately 300 kb at Xp22, including the BEND2, SCML2, and CDKL5 genes. In conclusion, our report suggests that searching for large rearrangements in CDKL5 should be considered in girls with early onset seizures and Rett‐like features. © 2009 Wiley‐Liss, Inc.
Nucleotide variation in central nervous system genes among male suicide attempters
Authors: Baca‐Garcia Enrique , Vaquero‐Lorenzo Concepción , Perez‐Rodriguez M. Mercedes , Gratacòs Mònica , Bayés Mònica , Santiago‐Mozos Ricardo , Leiva‐Murillo Jose Miguel , de Prado‐Cumplido Mario , Artes‐Rodriguez Antonio , Ceverino Antonio , Diaz‐Sastre Carmen , Fernandez‐Navarro Pablo , Costas Javier , Fernandez‐Piqueras José , Diaz‐Hernandez Montserrat , de Leon Jose , Baca‐Baldomero Enrique , Saiz‐Ruiz Jeronimo , Mann J. John , Parsey Ramin V. , Carracedo Angel , Estivill Xavier , Oquendo Maria A. 
Published: May 2009

AbstractDespite marked morbidity and mortality associated with suicidal behavior, accurate identification of individuals at risk remains elusive. The goal of this study is to identify a model based on single nucleotide polymorphisms (SNPs) that discriminates between suicide attempters and non‐attempters using data mining strategies. We examined functional SNPs (n = 840) of 312 brain function and development genes using data mining techniques. Two hundred seventy‐seven male psychiatric patients aged 18 years or older were recruited at a University hospital psychiatric emergency room or psychiatric short stay unit. The main outcome measure was history of suicide attempts. Three SNPs of three genes (rs10944288, HTR1E; hCV8953491, GABRP; and rs707216, ACTN2) correctly classified 67% of male suicide attempters and non‐attempters (0.50 sensitivity, 0.82 specificity, positive likelihood ratio = 2.80, negative likelihood ratio = 1.64). The OR for the combined three SNPs was 4.60 (95% CI: 1.31–16.10). The model's accuracy suggests that in the future similar methodologies may generate simple genetic tests with diagnostic utility in identification of suicide attempters. This strategy may uncover new pathophysiological pathways regarding the neurobiology of suicidal acts. © 2009 Wiley‐Liss, Inc.
A sequencing‐based survey of functional APAF1 alleles in a large sample of individuals with affective illness and population controls
Authors: Amin Zenab , Kanarek Katarzyna , Krupitsky Evgeny , Walderhaug Espen , Ilomäki Risto , Blumberg Hilary , Price Lawrence H. , Bhagwagar Zubin , Carpenter Linda L. , Tyrka Audrey R. , Magnusson Andres , Landrø Nils Inge , Zvartau Edwin , Gelernter Joel , Epperson C. Neill , Räsänen Pirkko , Siironen Jari , Lappalainen Jaakko 
Published: May 2009

AbstractRare apoptosis‐promoting functional variants in the apoptosis protease activating factor 1 (APAF1) gene were recently reported to co‐segregate with major depression in male members of families from Utah. In order to estimate the impact of these variants on risk for major depressive disorder (MDD) in the general population, we surveyed the frequency of the APAF1 putative MDD risk alleles using re‐sequencing in a large sample of northern European and European‐American subjects, including a large number of males with MDD. The E777K and N782T APAF1 variants previously described by Harlan et al. [Harlan et al. (2006) Mol Psychiatry 11(1):76–85] were found at low frequencies in affected individuals and population controls. The C450W and Q465R variants were not detected in any of the 632 subjects sequenced. These results show that the APAF1 variants associated with risk for MDD in the Utah pedigrees are very rare in Northern European and European‐American populations. In addition, the E777K and N782T variants were found at low frequencies both in patients and population controls, suggesting that these variants have limited impact on risk for MDD. © 2009 Wiley‐Liss, Inc.
Tin Chemistry.Fundamentals, Frontiers, and Applications. Herausgegeben von Alwyn G. Davies, Marcel Gielen, Keith H. Pannell und Edward R. T. Tiekink.
Authors: Dehnen Stefanie 
Published: May 2009

AbstractJohn Wiley & Sons, Chichester 2008. 752 S., geb., 199.00 €.—ISBN 978‐0470517710magnified image
Indirect Optical Analysis of a Dynamic Chemical System
Authors: Gasparini Giulio , Bettin Federico , Scrimin Paolo , Prins Leonard J. 
Published: May 2009

AbstractVersteckspiel: Die Gleichgewichtszusammensetzung einer dynamischen kovalenten Reaktion wird bestimmt, indem man die Restkonzentration einer Bezugsverbindung ermittelt (blau, siehe Bild). Das Abfangen dieser Bezugsverbindung führt zu einem charakteristischen UV/Vis‐Signal, das nicht von der Molekülstruktur der Zielverbindung abhängt.magnified image
Mirror‐Image Photoswitching of Individual Single‐Walled Carbon Nanotube Transistors Coated with Titanium Dioxide
Authors: Liu Song , Li Jianming , Shen Qian , Cao Yang , Guo Xuefeng , Zhang Guoming , Feng Chaoqun , Zhang Jin , Liu Zhongfan , Steigerwald Michael L. , Xu Dongsheng , Nuckolls Colin 
Published: May 2009

AbstractStimuliresponsive optoelektronische Einheiten werden aus den mit photoaktiven Quantenpunkten funktionalisierten Titeltransistoren erhalten. Bei den p‐Halbleiterröhren nimmt der Stromfluss unter UV‐Licht rasch ab und beim Abschalten der Bestrahlung reversibel wieder zu. Dagegen zeigen ambipolare Röhren spiegelbildliche Photoschalteffekte, wenn negative und positive Gatter‐Vorspannungen angewendet werden.magnified image
9,10‐Dihydro‐9,10‐diboraanthracene: Supramolecular Structure and Use as a Building Block for Luminescent Conjugated Polymers
Authors: Lorbach Andreas , Bolte Michael , Li Haiyan , Lerner Hans‐Wolfram , Holthausen Max C. , Jäkle Frieder , Wagner Matthias 
Published: May 2009

AbstractDreizentren‐Zweielektronen‐B‐H‐B‐Brücken kennzeichnen die neuartige polymere Struktur der Titelverbindung im Festkörper. Dieses Organoboran dient als effiziente Vorstufe für die Herstellung bordotierter π‐konjugierter Polymere durch Hydroborierungspolymerisation mit einem funktionalisierten 1,4‐Diethinylbenzol (siehe Bild). Diese Polymere bilden dünne Filme, die sich durch intensive grüne Lumineszenz auszeichnen.magnified image
Self‐Healing Colloidal Crystals
Authors: Iyer Ashlee St. John , Lyon L. Andrew 
Published: May 2009

AbstractHeilende Hände: Ein komplexes Zusammenspiel kolloidaler und polymerer Energetik bei der Selbstorganisation von Mikrogelen führt zur Bildung weicher kolloidaler Anordnungen mit Selbstheilungseigenschaften. Repulsive weiche Kugeln können in kolloidalen kristallinen Gittern stark komprimierte Konformationen ohne direkten Kontakt zu den nächsten Nachbarn annehmen (siehe Bild). Diese Fernwirkung ist direkte Ursache für die Selbstheilung der Assoziate.magnified image
Titelbild: Selectivity Control in Gold‐Mediated Esterification of Methanol (Angew. Chem. 23/2009)
Authors: Xu Bingjun , Liu Xiaoying , Haubrich Jan , Madix Robert J. , Friend Cynthia M. 
Published: May 2009

AbstractAuf Gold adsorbierte Sauerstoffatome erleichtern die Umwandlung von Methanol zu Methylformiat, Formaldehyd und Ameisensäure bei tiefen Temperaturen. Die Reaktionen finden an sauerstoffhaltigen Goldnanopartikeln mit ca. 2 nm Durchmesser statt, die bei der Oxidation einer Au(111)‐Oberfläche mit Ozon entstehen. Der genaue Reaktionsmechanismus wird von C. M. Friend und Mitarbeitern in ihrer Zuschrift auf S. 4270 ff. besprochen.magnified image
From Metal Binding to Nanoparticle Formation: Monitoring Biomimetic Iron Oxide Synthesis within Protein Cages using Mass Spectrometry
Authors: Kang Sebyung , Jolley Craig C. , Liepold Lars O. , Young Mark , Douglas Trevor 
Published: May 2009

AbstractMass measurements of metal‐mineralized protein cages allowed quantitative examination of the effects of metal‐ion concentration on the final nanoparticle size. Modeling using a kinetic master equation suggests that particle growth involves both a binding phase and a growth phase (see picture; I: relative abundance; LiDps: a DNA binding protein; nFe: number of Fe atoms).magnified image
Cooperative Molecular Motion within a Self‐Assembled Liquid‐Crystalline Molecular Wire: The Case of a TEG‐Substituted Perylenediimide Disc
Authors: Hansen Michael Ryan , Schnitzler Tobias , Pisula Wojciech , Graf Robert , Müllen Klaus , Spiess Hans Wolfgang 
Published: May 2009

AbstractAlways on the move: Molecular dynamics of perylene cores in columnar structures influences the processability and self‐healing of these materials. A combination of X‐ray scattering and advanced solid‐state NMR methods show that these systems have restricted angular mobility of the cores even in the frozen phase, and a cooperative spiral type of motion in the liquid crystalline phase (see picture).magnified image
Phosphonium Salts as Chiral Phase‐Transfer Catalysts: Asymmetric Michael and Mannich Reactions of 3‐Aryloxindoles
Authors: He Rongjun , Ding Changhua , Maruoka Keiji 
Published: May 2009

AbstractIt′s a PTC: A highly efficient reaction of 3‐aryloxindoles in an asymmetric Michael addition was achieved by using a quaternary tetraalkylphosphonium salt as a chiral phase‐transfer catalyst (PTC). The products were obtained in quantitative yields highee values. The reaction of 3‐aryloxindoles in an asymmetric Mannich reaction using the same catalyst also proved to be feasible.magnified image
Oxidative Carbocation Formation in Macrocycles: Synthesis of the Neopeltolide Macrocycle
Authors: Tu Wangyang , Floreancig Paul E. 
Published: May 2009

AbstractMacrocyclic oxocarbenium ions can be formed from macrolactones that contain benzylic or allylic ether groups through oxidative carbon–hydrogen‐bond activation mediated by 2,3‐dichloro‐4,5‐dicyanoquinone (DDQ). The applicability of this efficient reaction to complex‐molecule synthesis was demonstrated by its use in a brief formal synthesis of neopeltolide (see retrosynthetic scheme) to form the tetrahydropyrone ring.magnified image
Self‐Healing Colloidal Crystals
Authors: Iyer Ashlee St. John , Lyon L. Andrew 
Published: May 2009

AbstractHealing hands: A complex interplay between colloidal and polymeric energetics in microgel self‐assembly behavior results in soft colloidal assemblies with self‐healing properties. Repulsive soft spheres can adopt highly compressed conformations in colloidal crystalline lattices without directly contacting the nearest neighbors (see picture). This distant action is directly responsible for the self‐healing of the assemblies.magnified image
Practical Synthesis of the Dendralene Family Reveals Alternation in Behavior
Authors: Payne Alan D. , Bojase Gomotsang , Paddon‐Row Michael N. , Sherburn Michael S. 
Published: May 2009

AbstractBack from obscurity: The practical synthesis of the first six members of the fundamental class of acyclic branched oligoalkenes has been achieved. The syntheses allow access to the target compounds on multigram scales in good yields. Members of the family with even numbers of double bonds are significantly more stable than those with odd numbers (see picture), and exhibit different chemical reactivities in Diels–Alder reactions.magnified image
Photometric monitoring of the young star Par 1724 in Orion
Authors: Neuhäuser R. , Koeltzsch A. , Raetz St. , Schmidt T. O. B. , Mugrauer M. , Young N. , Bertoldi F. , Roell T. , Eisenbeiss T. , Hohle M. M. , Vaňko M. , Ginski C. , Rammo W. , Moualla M. , Broeg C. 
Published: May 2009

AbstractWe report new photometric observations of the ∼200 000 year old naked weak‐line run‐away T Tauri star Par 1724, located north of the Trapezium cluster in Orion. We observed in the broad band filters B, V, R, and I using the 90 cm Dutch telescope on La Silla, the 80 cm Wendelstein telescope, and a 25 cm telescope of the University Observatory Jena in Großschwabhausen near Jena. The photometric data in V and R are consistent with a ∼5.7 day rotation period due to spots, as observed before between 1960ies and 2000. Also, for the first time, we present evidence for a long‐term 9 or 17.5 year cycle in photometric data (V band) of such a young star, a cycle similar to that to of the Sun and other active stars (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Automated classification of Plasmodium sporozoite movement patterns reveals a shift towards productive motility during salivary gland infection
Authors: Hegge Stephan , Kudryashev Mikhail , Smith Ashley , Frischknecht Friedrich 
Published: May 2009

AbstractThe invasive stages of malaria and other apicomplexan parasites use a unique motility machinery based on actin, myosin and a number of parasite‐specific proteins to invade host cells and tissues. The crucial importance of this motility machinery at several stages of the life cycle of these parasites makes the individual components potential drug targets. The different stages of the malaria parasite exhibit strikingly diverse movement patterns, likely reflecting the varied needs to achieve successful invasion. Here, we describe a Tool for Automated Sporozoite Tracking (ToAST) that allows the rapid simultaneous analysis of several hundred motile Plasmodium sporozoites, the stage of the malaria parasite transmitted by the mosquito. ToAST reliably categorizes different modes of sporozoite movement and can be used for both tracking changes in movement patterns and comparing overall movement parameters, such as average speed or the persistence of sporozoites undergoing a certain type of movement. This allows the comparison of potentially small differences between distinct parasite populations and will enable screening of drug libraries to find inhibitors of sporozoite motility. Using ToAST, we find that isolated sporozoites change their movement patterns towards productive motility during the first week after infection of mosquito salivary glands.
Commercially viable resolution of ibuprofen
Authors: Chávez‐Flores David , Salvador James M. 
Published: May 2009

AbstractIbuprofen belongs to the non‐steroidal anti‐inflammatory drug (NSAID) family known as profens. Studies demonstrate that (S‐ibuprofen is 160 times more potent than (R‐ibuprofen in vitro, while the accumulation of (R‐ibuprofen can cause serious side effects such as gastrointestinal pain. Candida rugosa lipase was used to enantioselectively esterify racemic ibuprofen with decan‐1‐ol and butan‐1‐ol in cyclohexane with an enantiomeric ratio (E) of 130 and 46, respectively, in up to 46% conversion. Separation by bulb‐to‐bulb distillation of (R)‐ibuprofen and unreacted alcohol from the corresponding (S)‐alkyl ibuprofen ester was possible for the decyl but not the butyl case. The enantioselective hydrolysis of (S)‐alkyl ibuprofen esters with the same biocatalyst in aqueous phosphate buffer was twice as slow for the decyl alcohol versus the butyl example. The combined environmentally friendly enantioselective esterification and hydrolysis of ibuprofen insured the isolation of (S)‐ibuprofen with a greater than 99% enantiomeric excess.
Differentiation rather than aging of muscle stem cells abolishes their telomerase activity
Authors: O'Connor Matthew S. , Carlson Morgan E. , Conboy Irina M. 
Published: May 2009

AbstractA general feature of stem cells is the ability to routinely proliferate to build, maintain, and repair organ systems. Accordingly, embryonic and germline, as well as some adult stem cells, produce the telomerase enzyme at various levels of expression. Our results show that, while muscle is a largely postmitotic tissue, the muscle stem cells (satellite cells) that maintain this biological system throughout adult life do indeed display robust telomerase activity. Conversely, primary myoblasts (the immediate progeny of satellite cells) quickly and dramatically downregulate telomerase activity. This work thus suggests that satellite cells, and early transient myoblasts, may be more promising therapeutic candidates for regenerative medicine than traditionally utilized myoblast cultures. Muscle atrophy accompanies human aging, and satellite cells endogenous to aged muscle can be triggered to regenerate old tissue by exogenous molecular cues. Therefore, we also examined whether these aged muscle stem cells would produce tissue that is “young” with respect to telomere maintenance. Interestingly, this work shows that the telomerase activity in muscle stem cells is largely retained into old age wintin inbred “long” telomere mice and in wild‐derived short telomere mouse strains, and that age‐specific telomere shortening is undetectable in the old differentiated muscle fibers of either strain. Summarily, this work establishes that young and old muscle stem cells, but not necessarily their progeny, myoblasts, are likely to produce tissue with normal telomere maintenance when used in molecular and regenerative medicine approaches for tissue repair. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009