bluuebunny/crossref_metadata_2025_split huggingface dataset:
FORMULASI DAN UJI MUTU FISIKA KIMIA SEDIAAN KRIM MUPIROCIN MENGGUNAKAN EMULGATOR PADA KONSENTRASI YANG BERBEDA
Authors: Yulis Adriana  , Rona Rohmawan  
Published: April 2024

ABSTRAK

Telah dilakukan formulasi dan uji mutu fisika kimia sediaan krim mupirocin menggunakan dua emulgator pada konsentrasi yang berbeda. Penelitian ini bertujuan untuk mengetahui pengaruh nilai hydrophylic-lipophylic balance terhadap mutu fisika dan kimia dari krim mupirocin dengan perbandingan dari produk market leader. Formulasi krim ini menggunakan dua emulgator yaitu cera de lanol dan stearyl alkohol dengan konsentrasi yang berbeda. Penelitian ini termasuk penelitian eksperimental meliputi formulasi, uji fisika (uji organoleptis, homogenitas, daya sebar, viskositas, dan uji daya lekat), dan uji kimia (uji pH dan uji ketetapan kadar) serta uji statistik anova one way. Hasil penelitian ini menunjukan sediaan krim formulasi 1 memiliki pH 6,7, viskositas 14.000 cPs, daya sebar 35,23 cm2, daya lekat 1,36 detik, nilai HLB 13,35 dan kadar 109,94%, untuk krim formula 2 memiliki pH 6,29, viskositas 16,200 cPs, daya sebar 34,90 cm2, daya lekat selama 1,55 detik, nilai HLB 12,26 dan kadar 103,18 % dan untuk krim market leader memiliki pH 6,24, viskositas 15.800 cPs daya sebar 35,23 cm2, daya lekat selama 1,40 detik dan kadar 92,71 %. Formulasi 2 krim mupirocin tidak berbeda significant dengan produk market leader.

ABSTRACT
Formulations and chemical quality tests of mupirocin cream preparations have been carried out using two emulgators at different concentrations. This study aims to determine the effect of hydrophylic-lipophylic balance values on the physical and chemical quality of mupirocin cream with a comparison of market leader products. This cream formulation uses two emulgators, namely cera de lanol and stearyl alcohol with different concentrations. This research includes experimental research including formulations, physical tests (organoleptic tests, homogeneity, dispersion, viscosity, adhesion and hedonic tests), and chemical tests (pH test and assay test) and one-way anova statistical tests. The results of this study showed cream formulation 1 had a pH of 6.7, viscosity of 14,000 cPs, spread of 35.23 cm2, adhesion of 1.36 seconds, HLB value of 13.35 and concentration of 109.94%, for cream formula 2 had a pH 6.29, viscosity of 16,200 cPs, spreadability of 34.90 cm2, adhesion of 1.55 seconds, HLB value of 12.26 and grade of 103.18% and for cream market leader has a pH of 6.24, viscosity of 15,800 cPs of scattered power 35.23 cm2, adhesion for 1.40 seconds and the content of 92.71%.
PERANCANGAN SISTEM INFORMASI PROGRAM APPROVAL REQUEST (PAR) BERBASIS WEB PT MITRA SEJUK SELARAS (MSS)
Authors: Purwanto  , Ainun Rahmah  , Muhammad Zuhriyanto  , Nidjo Sandjojo  
Published: April 2024

Penelitian ini bertujuan untuk merancang sistem informasi Program Approval Request (PAR) pada PT. Mitra Sejuk Selaras (MSS). PAR merupakan kegiatan permohonan dan permintaan dana yang meliputi proses pengajuan formulir permohonan dana, pembuatan PAR, mengontrol serta proses pengajuan PAR, pengesahan atau persetujuan PAR, transfer dana dan arsip data pengajuan permohonan dana. Proses permintaan permohonan dana pada PT. Mitra Sejuk Selaras masih menggunakan sistem yang masih manual sehingga mengalami hambatan seperti laporan rekap data yang tidak valid, proses pembuatan PAR yang tidak efisien. Sistem informasi PAR dirancang menggunakan Unified Modelling Language (UML) yang meliputi data use case diagram, activity diagram, sequence diagram, class diagram dan dikembangkan menggunakan bahasa pemrograman PHP dan MySql sebagai database. Sistem informasi ini diharapkan dapat membantu dalam proses permohonan dan permintaan dana secara efektif dan efisien serta mempermudah user mengendalikan seluruh kegiatan dalam proses pengeluaran dana.
Analisis Zat Hidroquinon Pada Krim Pemutih Menggunakan Spektrofotometri UV-VIS
Authors: - Jihan Hamidah 
Published: April 2024

Kosmetik merupakan produk yang digunakan untuk mempercantik penampilan wajah. Saat ini, berbagai kosmetik semakin banyak bermunculan. Salah satu jenis kosmetik adalah krim pemutih. Krim pemutih mengandung zat aktif yang dapat mencerahkan flek hitam di kulit. Hidrokuinon merupakan obat keras serta pemakaiannya harus berdasarkan resep dokter. Pemakaian hidrokuinon dalam sediaan kosmetik yang dijual bebas dilarang tetapi boleh digunakan dengan konsentrasi 2% di bawah pengawasan dokter. Tujuan review untuk mengetahui kadar hidrokuinon dalam sediaan krim menggunakan spektrofotometri uv-vis. Metode penelitian ini adalah artikel review, menggunakan metode studi literatur. Pengumpulan data menggunakan instrumen online pada Google Scholar, Google. Data yang digunakan dalam penelitian ini adalah data sekunder yang bersumber dari literatur maupun referensi lainnya. Kriteria jurnal yang direview adalah jurnal nasional terbitan 10 tahun terakhir. hasil uji kuantitatif menggunakan spektrometri uv-vis krim pemutih wajah yang diuji mengandung hidrokuinon dalam kadar yang bervariasi dan pada beberapa sampel krim pemutih wajah terdeteksi positif mengandung hidrokuinon.
Perbandingan Kualitas Pembelajaran Selama Pandemi Covid-19 Pada Prodi Teknik Sipil Dan Farmasi Institut Sains Dan Teknologi Al-Kamal
Authors: Arthono Andri 
Published: April 2024

Tujuan dari penelitian ini adalah untuk membandingkan kendala selama perkuliahan, kualitas pengajaran dosen terhadap minat mahasiswa dalam pembelajaran jarak jauh pada masa pandemi Covid-19 di bidang teknik sipil, dan departemen farmasi di Institut Sains dan Teknologi Al Kamal. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan desain cross-sectional. Penentuan sampel dalam penelitian ini dengan menggunakan teknik judgement sampling atau sampling intensional maka diperoleh besar sampel yaitu 118 responden mahasiswa jurusan teknik sipil dan farmasi yang masih aktif pada semester genap tahun 2020-2. Pengolahan data dilakukan dengan menyajikan seluruh jawaban kuesioner dan membagi responden menjadi dua kelompok. Permasalahan yang paling banyak dihadapi oleh mahasiswa teknik sipil adalah sinyal internet (66%), jadwal kerja (19%), dan waktu perkuliahan (9%). Berdasarkan hasil survei diketahui bahwa dosen kedua departemen memiliki kualitas mengajar yang baik, dapat memberikan contoh, dapat berinteraksi dengan baik, dan dapat memberikan perkuliahan online seperti perkuliahan tatap muka. Sebanyak 57% mahasiswa teknik sipil dan 68% mahasiswa farmasi tertarik belajar online.

Kata kunci: Kualitas Pembelajaran, Mahasiswa, Perkuliahan Daring
Kata kunci: Kualitas Pembelajaran, Mahasiswa, Perkuliahan Daring
Milli İktisat Anlayışı Çerçevesinde Erken Cumhuriyet Döneminde İnhisarların İncelenmesi: Liman İnhisarları Örneği
Authors: AYDEMİR Burak , TOL Ümit Nazım 
Published: April 2024

Bu çalışmada, erken cumhuriyetin 1923-1929 arasını kapsayan döneminde, inhisarlar ele alınarak inhisar uygulamalarına yönelik politikaların gelişimine ve milli iktisat anlayışı ile ilişkisine dair bir değerlendirme yapılması amaçlanmıştır. İnhisar uygulamalarının, liman inhisarları özelinde incelendiği çalışmada milli iktisat düşüncesinin Osmanlı’dan cumhuriyete gelişiminin ortaya konması amacıyla ilgili anlayışın tarihsel arka planı kapsamında imparatorlukta 19. yüzyılın ikinci yarısı itibariyle bir ihtiyaç olarak gündeme gelen dış borç konusu ve II. Meşrutiyet dönemi içerisinde gayrimüslim nüfusun ticari faaliyetlerde belirgin biçimde egemen konuma gelmesini sağlayan sebepler, I. Dünya Savaşı ile birlikte milli iktisat anlayışına uygun olarak tesis edilen politikalar ve milli iktisat anlayışının yeni rejimin politika yapıcıları tarafından da bir iktisat zihniyeti olarak benimsenmesi ele alındıktan sonra erken cumhuriyetin çalışmaya konu olan döneminde limanları ilgilendiren idari ve yasal düzenlemeler ve liman inhisarları incelenmiştir. Nitel araştırma yöntemlerinden doküman analizinin yöntem olarak belirlendiği çalışmada elde edilen bulgulara, birincil ve ikincil kaynakların incelenmesiyle ulaşılmıştır. Bulguların değerlendirilmesiyle ulaşılan sonuç, yeni rejimin ilan edilmesiyle birlikte liman inhisarlarına yönelik oluşturulan politikaların milli iktisat anlayışı rehberliğinde tesis edildiğidir.
The Spirit in the letter: Pentecostalism and theological education
Authors: Asamoah-Gyadu J. K. Asamoah-Gyadu 
Published: April 2024

This article reflects on the relationship between the experience of the Holy Spirit which defines Pentecostalism and theological education which has normally been associated with the academic impanation of theology. I will argue that the Pentecostal/charismatic movement has always been suspicious of academic theological education on the basis of the argument that it often neglects spiritual experience by imparting head knowledge to the neglect of matters of the Spirit. In the same vein members of the historic mission churches-both Catholic and Protestant, have often chided Pentecostals for neglecting theological education preferring 10 build churches and provide leadership on the basis of experience
Bahasa Arab Dan Urgensinya Mempelajari Al-Qur’an
Authors: Ridwan Endan Hamdan 
Published: April 2024

Pembelajaran bahasa Arab berbasis Al-Qur’an tidak semata-mata dirancang untuk mendekatkan tujuan awal diformulasikan dan dikembangkannya ilmu bahasa Arab. Akan tetapi, secara fungsional dan pragmatik, orientasi utama mayoritas pemelajar bahasa Arab itu belajar dan menekuni bahasa Arab adalah untuk pemahiran keterampilan membaca teks, membaca literatur dan sumber-sumber ajaran Islam yang tidak terlepas dari ilmu nahu dan saraf. Hal ini juga sejalan dengan wahyu pertama yang turun kepada Nabi SAW, yaitu perintah membaca (iqra’) (QS al-‘Alaq/96: 1 dan 3). Perintah ini tidak hanya memberi isyarat terkait pentingnya membaca, baik tertulis (ayat-ayat Qur’aniyyah) maupun yang tidak tertulis (ayat-ayat kauniyyah), tetapi juga menunjukkan signifikansi orientasi maharah al-qira’ah (keterampilan membaca). Melalui pembelajaran bahasa Arab berbasis Al-Qur’an, selain contoh-contoh dari ayat-ayat Al-Qur’an dapat dijadikan model dalam penambahan, peningkatan, pengayaan kosakata baru, pengkaidahan nahwu dan sharaf, penghayatan keindahan balaghahnya, kontekstualisasi penerjemahannya, dan latihan-latihan kebahasa araban lainnya yang memperkuat keterampilan berbasaha Arab. Al-Qur’an sebagai basis pembelajaran bahasa Arab sejatinya membuka lahan baru berupa pengembangan korpus linguistik Al-Qur’an, sehingga penelitian dan pengembangan keilmuan bahasa Arab.
АБАЙ ШЫҒАРМАЛАРЫНДАҒЫ АҚЫЛ-ОЙДЫҢ КҮШІ, БІЛІМНІҢ ПАЙДАСЫ, ҒЫЛЫМНЫҢ ОРНЫ ТУРАЛЫ
Authors: Искендерова Когаршин 
Published: April 2024

Мақалада ұлы ойшыл, ақын Абай Құнанбайұлының ақыл, ғылым, білім жайлы айтқан ойларының бүгінгі күнге дейін маңызын жоймай келе жатқандығы туралы баяндалады. Соңғы кездері ұлылардың тарихтағы орындарына күмән келтіріп, жастардың санасын улап жүрген кейбір зерттеушілердің пікіріне қарсы ұлы ақыннның баға жетпес мұраларын ұлықтау көзделді. Ақылды , ойлы жас болудың қадамдарын Абай мұрасын оқу арқылы танып, тіпті «Толық адам» іліміндегі толық адам дәрежесіне көтерілу сатыларының кезеңдері көрсетілді.Сондай-ақ ,мақалада қаншама ғасыр өтсе де Абай Құнанбайұлының айтқан ғақлия сөздері мәнін жоймай, керісінше,халқының санасында жыл өткен сайын жаңғырып, мәңгі жасай беретіні туралы айтылды.
DEVELOPING STUDENTS' SKILLS TO JUSTIFY THEIR DECISIONS THROUGH THE IMPLEMENTATION OF RESEARCH TASKS
Authors: Alzhanova BAKYT 
Published: April 2024

This research describes how high school students can develop the skills to justify their decisions by completing research tasks. According to the results of the international PISA exam for several years, 15-year-old schoolchildren in Kazakhstan have low skills in analysis, synthesis and assessment according to Bloom's taxonomy. Based on this, ways were sought to develop the high skills of students of Nazarbayev Intellectual School in Aktobe. The study was carried out for one year. One of the reasons for choosing this topic is that it allows students to apply the principle of analysis in advanced mathematics classes by conducting research, deepening their knowledge and establishing interdisciplinary connections with physics. The purpose of the study is to develop the communication skills of students, teach them to solve text problems in mathematics, use knowledge in real life effectively. Methods used in the study are collection of quantitative data through questionnaires, collection of qualitative data from students' communication through observation of the lesson. First of all, the results of the international PISA study and the results of CITO monitoring were studied. At the same time, according to the results of the CITO monitoring the skills of knowledge, understanding and application showed 100% each, a comparative analysis showed 82%, synthesis skills 67%, skills assessment 48%. The survey was conducted on the Microsoft Forms platform. A total of 62 students took part. CLIL technologies, Problem-Based Learning, and the LearningApps platform were used. The results of the study were presented at the school pedagogical council.
ВАЖНОСТЬ ИСПОЛЬЗОВАНИЯ ЦИФРОВЫХ ТЕХНОЛОГИЙ НА УРОКЕ ИНФОРМАТИКИ
Authors: Жаржанова Жайнагуль 
Published: April 2024

В статье рассматривается обучение школьной информатике в условиях цифровизации образования. Использование цифровых образовательных технологий для развития системы общего образования является одним из важнейших стратегических направлений в области повышения качества образования. На сегодняшний день применение цифровых технологий переживает этап своего развития. Актуальность данной модели подкрепляется приоритетным проектом «Современная цифровая образовательная среда». Целью данного государственного проекта является создание условий для непрерывного образования на базе цифровой платформы онлайн-образования. Существуют различные виды цифровых технологий в образовании, которые при правильном использовании в организации и управлении образовательным процессом обеспечивают достижение высокой эффективности.Современные технологии и телекоммуникации позволяют изменить характер организации учебно-воспитательного процесса, полностью погрузить обучаемого в информационно-образовательную среду, повысить качество образования, мотивировать процессы восприятия информации и получения знаний.Эти технологии позволяют внедрять новые методики обучения и ориентироваться на предпочтения школьников, что способствует привлечению отстающих учащихся и повышает их образовательные результаты. Адаптивное и интерактивное обучение позволяет достичь наиболее высокого уровня освоения материала.
Association between passing return-to-sport testing and re-injury risk in patients after anterior cruciate ligament reconstruction surgery: a systematic review and meta-analysis
Authors: Zhou Wenqi , Liu Xihui , Hong Qiaomei , Wang Jingping , Luo Xiaobing 
Published: April 2024

Background
Inconsistent results have been obtained regarding the association between return-to-sport (RTS) testing and the risk of subsequent re-injury following anterior cruciate ligament reconstruction (ACLR). We therefore conducted a systematic review and meta-analysis to assess the potential association between passing of RTS and the risk of re-injury for patients after ACLR.

Methods
This meta-analysis was registered in INPLASY with the registration number INPLASY202360027. The electronic databases MedLine, EmBase, and the Cochrane library were systematically searched to identify eligible studies from their inception up to September 2023. The investigated outcomes included knee injury, secondary ACL, contralateral ACL injury, and graft rupture. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using the random-effects model.

Results
A total number of nine studies involving 1410 individuals were selected for the final quantitative analysis. We noted that passing RTS test was not associated with the risk of subsequent knee injury (OR: 0.95; 95% CI: 0.28–3.21; P = 0.929), secondary ACL injury (OR: 0.98; 95% CI: 0.55–1.75; P = 0.945), and contralateral ACL injury (OR: 1.53; 95% CI: 0.63–3.71; P = 0.347). However, the risk of graft rupture was significantly reduced (OR: 0.49; 95% CI: 0.33–0.75; P = 0.001).

Conclusions
This study found that passing RTS test was not associated with the risk of subsequent knee injury, secondary ACL injury, and contralateral ACL injury, while it was associated with a lower risk of graft rupture. Thus, it is recommended that patients after ACLR pass an RTS test in clinical settings.
Therapeutic Advancement in Treatment and Prevention of Nipah Viral Infection: A Review
Authors: Kallon Mary K. , Mami Daniel Maada , Mami Emmanuel Tom , Romba Mariam , Andrew M. Patrick , Martain M. Sylvester 
Published: April 2024

The Nipah virus (NiV) is an emerging zoonotic pathogen that poses a major risk to global health, with a high mortality rate and the potential for wide outbreaks. NiV, which originated in fruit bats, has shown a concerning potential to infect humans and cause serious respiratory and neurological disorders. The virus has a pleomorphic structure and a broad host range, preventing efforts to understand and regulate its pathogenesis. This review discusses current advances in the prevention and management of NiV, including the efficacy of several antiviral therapies in vitro and in vivo. Treatments such as Ribavirin, Favipiravir, Acyclovir, Remdesivir, and Balapiravir have produced varying results, whilst monoclonal antibodies such as m102.4, h5B3.1, and nAH1.3 provide effective neutralization but require additional testing in humans. In addition, innovative vaccination techniques such as recombinant measles virus, subunit vaccines, vector vaccines, and the novel mRNA-1215 vaccine have shown success in preclinical and early clinical trials. To reduce the risk of human transmission, preventive measures include early outbreak detection through improved surveillance systems, exposure-based screening, and educational activities. This covers vital guidelines like avoiding raw date palm sap during outbreak seasons and using physical barriers to prevent bat-to-human transmission, which is vital for controlling this deadly virus.
The role of current mood and stop rules on physical task performance: An experimental investigation in patients with work‐related upper extremity pain
Authors: Karsdorp Petra A. , Nijst Saskia E. , Goossens Mariëlle E.J.B. , Vlaeyen Johan W.S. 
Published: August 2009

ABSTRACTPatients with work‐related upper extremity pain (WRUED) experience disability in daily life activities. The factors that influence levels of disability are still unclear. Both excessive avoidance and persistence have been suggested, but the affective and motivational processes that underlie these behaviours have not been scrutinized. This study was aimed at examining the role of current mood and stop rules on physical task performance, controlling for gender, pain severity, pain catastrophizing, and pain‐related fear. An additional focus was the role of the interaction between current mood and stop rules as predicted by the novel Mood‐as‐Input (MAI) model. Following MAI, it is the informational value of current mood within a goal context (stop rule), rather than mood per se that predicts behaviour. A 2 (mood)×2 (stop rule)×2 (physical task order) factorial design was used in which 62 WRUED patients performed an upper and lower extremity physical task. A stress interview was used to induce positive and negative mood. Patients received either an “as‐much‐as‐can (AMAC)” stop rule instruction, or a “feel‐like‐discontinuing (FLDC)” stop rule instruction. Results showed that physical task performance was predicted by pain‐related fear, current mood, stop rule. However, the predicted mood×stop rule interaction was not found, and there was no influence of gender, pain severity, and pain catastrophizing on task performance. The findings suggest that not only pain‐related fear, but current mood and goal context factors independently affect physical performance in patients with WRUED.
Vaginal delivery of breech presentation
Authors: Kotaska Andrew , Menticoglou Savas , Gagnon Robert , Farine Dan , Basso Melanie , Bos Hayley , Delisle Marie‐France , Grabowska Kirsten , Hudon Lynda , Mundle William , Murphy‐Kaulbeck Lynn , Ouellet Annie , Pressey Tracy , Roggensack Anne 
Published: August 2009

AbstractObjectivesTo review the physiology of breech birth; to discern the risks and benefits of a trial of labour versus planned Caesarean section; and to recommend to obstetricians, family physicians, midwives, obstetrical nurses, anaesthesiologists, pediatricians, and other health care providers selection criteria, intrapartum management parameters, and delivery techniques for a trial of vaginal breech birth.OptionsTrial of labour in an appropriate setting or delivery by pre‐emptive Caesarean section for women with a singleton breech fetus at term.OutcomesReduced perinatal mortality, short‐term neonatal morbidity, long‐term infant morbidity, and short‐ and long‐term maternal morbidity and mortality.EvidenceMedline was searched for randomized trials, prospective cohort studies, and selected retrospective cohort studies comparing planned Caesarean section with a planned trial of labour; selected epidemiological studies comparing delivery by Caesarean section with vaginal breech delivery; and studies comparing long‐term outcomes in breech infants born vaginally or by Caesarean section. Additional articles were identified through bibliography tracing up to June 1, 2008.ValuesThe evidence collected was reviewed by the Maternal Fetal Medicine Committee of the Society of Obstetricians and Gynaecologists of Canada (SOGC) and quantified using the criteria and classifications of the Canadian Task Force on Preventive Health Care.ValidationThis guideline was compared with the 2006 American College of Obstetrician's Committee Opinion on the mode of term singleton breech delivery and with the 2006 Royal College of Obstetrician and Gynaecologists Green Top Guideline: The Management of Breech Presentation. The document was reviewed by Canadian and International clinicians with particular expertise in breech vaginal delivery.SponsorsThe Society of Obstetricians and Gynaecologists of Canada.
Drawing statistical inferences from historical census data, 1850–1950
Authors: Davern Michael , Ruggles Steven , Swenson Tami , Alexander J. Trent , Oakes J. Michael 
Published: August 2009

AbstractVirtually all quantitative microdata used by social scientists derive from samples that incorporate clustering, strati cation, and weighting adjustments (Kish 1965, 1992). Such data can yield standard error estimates that differ dramatically from those derived from a simple random sample of the same size. Researchers using historical U.S. census microdata, however, usually apply methods designed for simple random samples. The resulting p values and confidence intervals could be inaccurate and could lead to erroneous research conclusions. Because U.S. census microdata samples are among the most widely used sources for social science and policy research, the need for reliable standard error estimation is critical. We evaluate the historical microdata samples of the Integrated Public Use Microdata Series (IPUMS) project from 1850 to 1950 in order to determine (1) the impact of sample design on standard error estimates, and (2) how to apply modern standard error estimation software to historical census samples. We exploit a unique new data source from the 1880 census to validate our methods for standard error estimation, and then we apply this approach to the 1850–1870 and 1900–1950 decennial censuses. We conclude that Taylor series estimation can be used effectively with the historical decennial census microdata samples and should be applied in research analyses that have the potential for substantial clustering effects.