bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancements of eco‐friendly natural antimicrobial agents and their transformative role in sustainable textiles
Authors: Hossain Md Monir , Islam Tarikul , Jalil M. Abdul , Rakibuzzaman Sheikh Md , Surid S. M. , Zabed Md Riad Ibne , Talukder Amit , Hossain Shahin 
Published: May 2024

AbstractIn the face of mounting environmental concerns, the textile industry is undergoing a pivotal transformation, with sustainability at the forefront of innovation. This review focuses on the exploration of natural compounds, renowned for their antimicrobial properties, as viable alternatives to conventional chemical agents that pose significant environmental challenges. It delves into a diverse array of natural sources, including plant extracts, essential oils, and microbial‐derived compounds, which have been identified for their potent antimicrobial efficacy. These natural agents not only demonstrate a broad spectrum of activity against pathogenic microorganisms but also represent a stride towards eco‐friendly textile processing by offering a sustainable substitute for synthetic antimicrobials. The integration of these green antimicrobial agents into textiles is scrutinized, with a particular emphasis on their impact on enhancing fabric functionalities. This includes improvements in durability, wash resistance, and the sustained antimicrobial effectiveness of treated fabrics, without sacrificing environmental integrity. Moreover, the study underscores the potential health benefits of these natural agents, such as a decrease in allergic reactions and skin irritations commonly associated with traditional antimicrobial treatments. The review culminates by highlighting the significant role these eco‐conscious solutions play in revolutionizing antimicrobial textiles, promoting industry‐wide sustainable practices, and catering to the escalating consumer demand for environmentally responsible products.Highlights
Provides eco‐friendly and sustainable alternatives in textile processing, offering a greener choice over synthetic options.
Enhances fabric functionality while preserving environmental integrity, addressing sustainability concerns throughout production.
Improves fabric durability, wash resistance, and long‐lasting efficacy, thereby contributing to superior product performance.
Reduces allergic reactions and skin irritations, underscoring the health benefits of eco‐friendly antimicrobial treatments.
Promotes sustainable practices, shaping the future of antimicrobial textiles and catering to the growing demand for environmentally conscious consumer choices in the industry.
Definition, risk factors, and outcome analysis of prolonged mechanical ventilation in children
Authors: Chen Ruonan , Liu Yanling , Dang Hongxing 
Published: May 2024

AbstractObjectiveThis study aims to explore the time threshold for defining prolonged mechanical ventilation (PMV) in children, along with its risk factors and outcomes.MethodsA prospective cohort study was conducted on children aged 29 days–18 years, who were consecutively admitted to two Pediatric Intensive Care Units (PICUs) at Children's Hospital of Chongqing Medical University, from October 2020 to June 2021. The study included patients receiving mechanical ventilation (MV) for more than 2 days (each day >6 h). Participants were divided into five groups based on the duration of MV (2–7 days, 8–14 days, 15–21 days, 21–30 days, >30 days) to compare rates of extubation failure, all‐cause mortality one month post‐discharge, incidence of ventilator‐associated pneumonia, tracheotomy rates, total hospital stay, PICU stay, and overall hospital costs. The most clinically and statistically significant outcome variables were selected. The Youden index was used to determine the MV duration with the most significant impact on overall outcomes, defining this as PMV. Baseline characteristics, treatment information, and outcomes were compared between PMV and non‐PMV groups. Univariate and multivariate logistic regression analyses were used to identify risk factors for PMV occurrence.ResultsA total of 382 subjects were included in the study. The distribution of children across the five MV duration groups was 44.2%, 27.7%, 10.7%, 8.9%, and 8.4% respectively. The rates of at least one extubation failure in each group were 5.9%, 10.4%, 41.5%, 41.2%, and 46.9% (p < .05). Statistically significant differences were observed among groups in terms of tracheotomy rates, all‐cause mortality at 1 month postdischarge, median total hospital stay, median PICU stay, and hospital costs (p < .05). Defining PMV, the most appropriate time point calculated was 12.5 days, based on at least one extubation failure and/or death within 1 month postdischarge. Higher PIM‐3 scores, weight for age <−2SD, admission for respiratory distress/insufficient ventilation and/or hemodynamic instability/shock/arrhythmia, noninvasive ventilation on the first day, and undergoing blood transfusion treatment were identified as risk factors for PMV (p < .05).ConclusionIn children, MV for ≥13 days significantly increases mortality rates, extubation failure and tracheotomy rates, duration of PICU and total hospital stay and costs. We suggest defining PMV as MV ≥13 days, particularly for children undergoing MV for respiratory illnesses. This definition can assist clinicians in developing appropriate treatment strategies by focusing on risk factors and providing reliable prognostic consultation to patients' families.
Methods and clinical biomarker discovery for targeted proteomics using Olink technology
Authors: Wang Han , Zhao Tian , Zeng Jingjing , Zhang Ruijie , Pu Liyuan , Qian Suying , Xu Shan , Jiang Yannan , Pan Lifang , Dai Xiaoyu , Guo Xu , Han Liyuan 
Published: May 2024

AbstractPurposeThis paper is to offer insights for designing research utilizing Olink technology to identify biomarkers and potential therapeutic targets for disease treatment.Experimental DesignWe discusses the application of Olink technology in oncology, cardiovascular, respiratory and immune‐related diseases, and Outlines the advantages and limitations of Olink technology.ResultsOlink technology simplifies the search for therapeutic targets, advances proteomics research, reveals the pathogenesis of diseases, and ultimately helps patients develop precision treatments.ConclusionsAlthough proteomics technology has been rapidly developed in recent years, each method has its own disadvantages, so in the future research, more methods should be selected for combined application to verify each other.
Photo‐Stimulated Zn‐based Batteries: Progress, Challenges, and Perspectives
Authors: Wang Xinyue , Ding Yi , Yu Xinxin , Dai Peng , Bai Zhiman , Wu Mingzai , Jiang Tongtong 
Published: May 2024

AbstractSolar energy, as a renewable energy source, dominates the vast majority of human energy, which can be harvested and converted by photovoltaic solar cells. However, the intermittent availability of solar energy restricts the actual utilization circumstances of solar cells. Integrating photo‐responsive electrodes into an energy storage device emerges as a dependable and executable strategy, fostering the creation of photo‐stimulated batteries that seamlessly amalgamate the process of solar energy collection, conversion, and storage in one system. Endowed by virtues such as cost‐effectiveness, facile manufacturing, safety, and environmental friendliness, photo‐stimulated Zn‐based batteries have attracted considerable attention. The progress report furnishes a brief overview, summarizing various photo‐stimulated Zn‐based batteries. Their configurations, operational principles, advancements, and the intricate engineering of photoelectrode designs are introduced, respectively. Through rigorous architectural design, photo‐stimulated Zn‐based batteries exhibit the ability to initiate charging by saving electricity usage, and in certain instances, even without the need for external electrical grids under illumination. Furthermore, the compensation of solar energy can be explored to improve the output electric energy. At last, opportunities and challenges toward photo‐stimulated Zn‐based batteries in the process of development are proposed and discussed in the hope of expanding their application scenarios and accelerating the commercialization progress.
Machine Learning Assisted Self‐Powered Identity Recognition Based on Thermogalvanic Hydrogel for Intelligent Security
Authors: Ma Xueliang , Wang Wenxu , Cui Xiaojing , Li Yunsheng , Yang Kun , Huang Zhiquan , Zhang Hulin 
Published: May 2024

AbstractIdentity recognition as the first barrier of intelligent security plays a vital role, which is facing new challenges that are unable to meet the need of intelligent era due to low accuracy, complex configuration and dependence on power supply. Here, a finger temperature‐driven intelligent identity recognition strategy is presented based on a thermogalvanic hydrogel (TGH) by actively discerning biometric characteristics of fingers. The TGH is a dual network PVA/Agar hydrogel in an H2O/glycerol binary solvent with [Fe(CN)6]3−/4− as a redox couple. Using a concave‐arranged TGH array, the characteristics of users can be distinguished adequately even under an open environment by extracting self‐existent intrinsic temperature features from five typical sites of fingers. Combined with machine learning, the TGH array can recognize different users with a high average accuracy of 97.6%. This self‐powered identity recognition strategy is further applied to a smart lock, attaining a more reliable security protection from biometric characteristics than bare passwords. This work provides a promising solution for achieving better identity recognition, which has great advantages in intelligent security and human‐machine interaction toward future Internet of everything.
Ion chromatography‐based determination of lithium in human urine for monitoring medication compliance
Authors: Kwon Nam Hee , Park Jaehyeong , Kim Seon Yeong , Ko Beom Jun , Cheong Jae Chul , Kim Jin Young 
Published: May 2024

AbstractContinuous Li monitoring is vital in ensuring the safety and treatment efficacy of probationers with psychotic disorders, such as bipolar disorder, depression, and mania. This study introduced a validated quantitative analysis method using ion chromatography (IC) to monitor Li+ concentration in urine. The methodology involved centrifuging the urine sample, diluting the supernatant with deionized water, and subsequent IC analysis using guard and analytical columns for precise Li+ concentration measurement. The method quantified Li+ within the range of 2–400 ng/mL, demonstrating its excellent linearity (r2 = 0.9983) with a weighting factor of 1/x. Precision levels below 12.8% were observed for both intraday and interday measurements with an accuracy of −5.9% to 15.2%. The detection limit was identified as 0.12 ng/mL. The method conformed to analytical standards in terms of selectivity, matrix effect, process efficiency, dilution integrity, and stability. Moreover, the method distinctly quantified Li+ while effectively eliminating interference from Na+, which had a similar retention time as Li+ with higher concentrations. Further, the developed method was successfully applied to analyze forensic urine samples of Li users, demonstrating its applicability for medication compliance monitoring using urine samples of mentally disordered probationers.
Impact of Cross‐Linking on the Physicochemical and Physiological Characteristics of Barnyard Millet (Echinochloa frumentacea) Grains Starch
Authors: Bhatt Pankaj , Singh Suruchi , Garg Sakshi , Ashoka P. , Mishra Shardandu Kumar , Kaushik Shikha , Deva Varsha , Goel Richa , Kumar Vipin 
Published: May 2024

Barnyard millet starch (Echinochloa frumentacea) has been investigated for its potential in drug delivery systems due to its unique properties. This study examined the physicochemical and physiological properties of cross‐linked barnyard millet starch (BMS) using varying concentrations of sodium tripolyphosphate (STPP). Physicochemical and physiological properties of the cross‐linked starches are analyzed. Cross‐linking resulted in reduced swelling capacity and solubility of starch samples. Morphological analysis revealed rough surfaces with cavities and minute cracks in cross‐linked starches. Acute and sub‐acute toxicity studies in test animals indicated no adverse effects, with LD50 values within acceptable limits at 2000 mg kg−1. Hematological, biochemical, and lipid profiles showed no significant alterations compared to the control group. The study demonstrated a low acute toxicity level and favorable safety profile for STPP‐cross‐linked starch. These findings highlighted the potential of cross‐linked barnyard millet starch as a carrier in drug delivery system and for food applications. This study supports the potential of cross‐linked barnyard millet starch in pharmaceutical formulations.
The impact of different length hooked‐end fibers on the structural performance of RC folded plates
Authors: Katlav Metin , Turk Kazim , Turgut Paki 
Published: May 2024

AbstractIn this article, the effect of hooked‐end fibers with different lengths on the structural performance of RC‐FPs fabricated from hybrid fiber‐reinforced self‐compacting concrete (HFR‐SCC) was investigated. For this purpose, a total of 15 full‐scale test samples having different plate thicknesses (60, 70, and 80 mm) were produced and tested under bending after a 90‐day curing period. Subsequently, load‐carrying capacity (Pp), flexural toughness (Fth), and deflection ductility index (μu) of all RC‐FPs were found using load‐deflection curves obtained from bending tests, while crack patterns were drawn from the samples tested. Besides, high‐precision contour plots are proposed to estimate the structural performance values of RC‐FPs depending on plate thickness and fiber reinforcing index. As a result, the best structural performance in RC‐FPs was obtained from the use of a longer hooked‐end steel fiber together with micro steel fiber as a hybrid, followed by the lower length hooked‐end steel fibers as singles. Specifically, irrespective of the plate thickness, the hybrid use of longer hooked steel fibers in combination with micro fibers increased the Pp, Fth, and μu values of RC‐FPs on average 1.67, 1.76, and 1.57 times, respectively, compared to the control specimens. As for when using the lower length hooked‐end fiber as single, the values of Pp, Fth, and μu increased on average 1.57, 1.69, and 1.30 times. Lastly, whereas plate thickness has little effect on improving the structural performance of thin‐walled carrier elements such as RC‐FPs, adding fibers in different lengths, aspect ratios, and combinations is much more effective. The collective test results demonstrate that using RC‐FPs made of HFR‐SCC in the roof carrier system of large span structures could improve structural performance, aesthetics, erection time, and earthquake behavior thanks to reduced dead load.
Functional mechanism of hypoxia‐like conditions mediating resistance to ferroptosis in cervical cancer cells by regulating KDM4A SUMOylation and the SLC7A11/GPX4 pathway
Authors: Xiong Jing , Chen Puxiang , He Ling , Chai Xiaoshan , Zhang Yongjing , Sun Shujuan 
Published: May 2024

AbstractThe discovery of ferroptosis has unveiled new perspectives for cervical cancer (CC) management. We elucidated the functional mechanism of hypoxia‐like conditions in CC cell ferroptosis resistance. CC cells were subjected to normoxia or hypoxia‐like conditions, followed by erastin treatment to induce ferroptosis. The assessment of cell viability/ferroptosis resistance was performed by MTT assay/Fe2+, MDA, and glutathione measurement by colorimetry. KDM4A/SUMO1/Ubc9/SENP1 protein levels were determined by Western blot. Interaction and binding sites between KDM4A and SUMO1 were analyzed and predicted by immunofluorescence/co‐immunoprecipitation and GPS‐SUMO 1.0 software, with the target relationship verified by mutation experiment. SLC7A11/GPX4/H3K9me3 protein levels, and H3K9me3 level in the SLC7A11 gene promoter region were determined by RT‐qPCR and Western blot/chromatin immunoprecipitation. H3H9me3/SLC7A11/GPX4 level alterations, and ferroptosis resistance after KDM4A silencing or KDM4A K471 mutation were assessed. Hypoxia‐like conditions increased CC cell ferroptosis resistance and KDM4A, SUMO1, and Ubc9 protein levels, while it decreased SENP1 protein level. KDM4A and SUMO1 were co‐localized in the nucleus, and hypoxia‐like conditions promoted their interaction. Specifically, the K471 locus of KDM4A was the main locus for SUMO1ylation. Hypoxia‐like conditions up‐regulated SLC7A11 and GPX4 expression levels and decreased H3K9me3 protein level and H3K9me3 abundance in the SLC7A11 promoter region. KDM4A silencing or K471 locus mutation resulted in weakened interaction between KDM4A and SUMO1, elevated H3K9me3 levels, decreased SLC7A11 expression, ultimately, a reduced CC cell ferroptosis resistance. CoCl2‐stimulated hypoxia‐like conditions enhanced SUMO1 modification of KDM4A at the K471 locus specifically, repressed H3K9me3 levels, and up‐regulated SLC7A11/GPX4 to enhance CC cell ferroptosis resistance.
Application of modified kaolinite in improving thermal stability of polydimethylsiloxane
Authors: Nguyen Linh T. T. , Jiang Zhong‐Tao , Mondinos Nicholas , Phan Tuan D. , No Kwangsoo , Liew Willey Yun Hsien 
Published: May 2024

AbstractThis research investigated the chemical structure and morphology of the hydrogenated tallow amine (HTA)‐intercalated kaolinite by XRD, FT‐IR, and TEM measurements. The experimental outcomes show that intercalation of kaolinite by HTA, with an intercalation rate of 63.2%, expands the interlayer distance with a subsequent dominant basal XRD peak at 2θ ≈ 7.9°. Furthermore, a composite was created from the HTA‐intercalated kaolinite and polydimethylsiloxane (PDMS) through a favorable interaction between the end silanol groups of PDMS and the modified kaolinite surface. Thermogravimetry‐differential scanning calorimetry results indicate that introducing the HTA‐intercalated kaolinite into the PDMS matrix increases the thermal stability of the composite from 178 to 343 °C. However, the thermal stability of the composite is lower than that of other published materials. The synthesis of kaolinite/PDMS composite with enhanced structural and thermal stability outcomes has been provided via a simple and effective solution method that should have further applications.
Life at the interface: Engineering bio‐nanomaterials through interfacial molecular self‐assembly
Authors: Miller Michael A. , Medina Scott 
Published: May 2024

AbstractInterfacial self‐assembly describes the directed organization of molecules and colloids at phase boundaries. Believed to be fundamental to the inception of primordial life, interfacial assembly is exploited by a myriad of eukaryotic and prokaryotic organisms to execute physiologic activities and maintain homeostasis. Inspired by these natural systems, chemists, engineers, and materials scientists have sought to harness the thermodynamic equilibria at phase boundaries to create multi‐dimensional, highly ordered, and functional nanomaterials. Recent advances in our understanding of the biophysical principles guiding molecular assembly at gas–solid, gas–liquid, solid–liquid, and liquid–liquid interphases have enhanced the rational design of functional bio‐nanomaterials, particularly in the fields of biosensing, bioimaging and biotherapy. Continued development of non‐canonical building blocks, paired with deeper mechanistic insights into interphase self‐assembly, holds promise to yield next generation interfacial bio‐nanomaterials with unique, and perhaps yet unrealized, properties.This article is categorized under:
Nanotechnology Approaches to Biology > Nanoscale Systems in Biology
Therapeutic Approaches and Drug Discovery > Emerging Technologies
Quantum tachyonic preheating, revisited
Authors: Tranberg Anders , Ungersbäck Gerhard 
Published: May 2024

Abstract
In certain models of inflation, the postinflationary reheating of the Universe is not primarily due to perturbative decay of the inflaton field into particles, but proceeds through a tachyonic instability. In the process, long-wavelength modes of an unstable field, which is often distinct from the inflaton itself, acquire very large occupation numbers, which are subsequently redistributed into a thermal equilibrium state. We investigate this process numerically through quantum real-time lattice simulations of the Kadanoff-Baym equation, using a 1/N-NLO truncation of the 2PI-effective action. We identify the early-time maximum occupation number, the “classical” momentum range, the validity of the classical approximation and the effective IR temperature, and study the kinetic equilibration of the system and the equation of state.
A nomogram for predicting choledochal cyst with perforation
Authors: Zhang Guangwei , Wang Haoming , Hu Jianyang , Yang Chenyu , Tan Bingqian , Hu Jiqiang , Zhang Mingman 
Published: May 2024

Abstract
Background
Choledochal cyst with perforation (CC with perforation) rarely occurs, early diagnosis and timely treatment plan are crucial for the treatment of CC with perforation. This study aims to forecast the occurrence of CC with perforation.

Methods
All 1111 patients were conducted, who underwent surgery for choledochal cyst at our hospital from January 2011 to October 2022. We conducted univariate and multivariate logistic regression analysis to screen for independent predictive factors for predicting CC with perforation, upon which established a nomogram. The predictive performance of the nomogram was evaluated using receiver operating characteristic (ROC) curves, calibration plots, and decision curve analysis (DCA) curves.

Results
The age of children with choledochal cyst perforation is mainly concentrated between 1 and 3 years old. Logistic regression analysis indicates that age, alanine aminotransferase, glutamyl transpeptidase, C-reactive protein, vomiting, jaundice, abdominal distension, and diarrhea are associated with predicting the occurrence of choledochal cyst perforation. ROC curves, calibration plots, and DCA curve analysis curves demonstrate that the nomogram has great discriminative ability and calibration, as well as significant clinical utility.

Conclusion
The age of CC with perforation is mainly concentrated between 1 and 3 years old. A nomogram for predicting the perforation of choledochal cyst was established.
Retrogasserian trigeminal radiofrequency-thermorhizotmoy for trigeminal neuralgia
Authors: Brinzeu A. , Sindou M. 
Published: May 2024

Abstract
Based on a personal experience of 4200 surgeries, radiofrequency thermocoagulation is useful lesional treatment for those trigeminal neuralgias (TNs) not amenable to microvascular decompression (idiopathic or secondary TNs). Introduced through the foramen ovale, behind the trigemnial ganglion in the triangular plexus, the needle is navigated by radiology and neurophysiological testing to target the retrogasserian fibers corresponding to the trigger zone. Heating to 55–75 °C can achieve hypoesthesia without anaesthesia dolorosa if properly controlled. Depth of anaesthesia varies dynamically sedation for cannulation and lesioning, and awareness during neurophysiologic navigation. Proper technique ensures long-lasting results in more than 75% of patients.