bluuebunny/crossref_metadata_2025_split huggingface dataset:
The applications of nature‐inspired algorithms in Internet of Things‐based healthcare service: A systematic literature review
Authors: Amiri Zahra , Heidari Arash , Zavvar Mohammad , Navimipour Nima Jafari , Esmaeilpour Mansour 
Published: May 2024

AbstractNature‐inspired algorithms revolve around the intersection of nature‐inspired algorithms and the IoT within the healthcare domain. This domain addresses the emerging trends and potential synergies between nature‐inspired computational approaches and IoT technologies for advancing healthcare services. Our research aims to fill gaps in addressing algorithmic integration challenges, real‐world implementation issues, and the efficacy of nature‐inspired algorithms in IoT‐based healthcare. We provide insights into the practical aspects and limitations of such applications through a systematic literature review. Specifically, we address the need for a comprehensive understanding of the applications of nature‐inspired algorithms in IoT‐based healthcare, identifying gaps such as the lack of standardized evaluation metrics and studies on integration challenges and security considerations. By bridging these gaps, our paper offers insights and directions for future research in this domain, exploring the diverse landscape of nature‐inspired algorithms in healthcare. Our chosen methodology is a Systematic Literature Review (SLR) to investigate related papers rigorously. Categorizing these algorithms into groups such as genetic algorithms, particle swarm optimization, cuckoo algorithms, ant colony optimization, other approaches, and hybrid methods, we employ meticulous classification based on critical criteria. MATLAB emerges as the predominant programming language, constituting 37.9% of cases, showcasing a prevalent choice among researchers. Our evaluation emphasizes adaptability as the paramount parameter, accounting for 18.4% of considerations. By shedding light on attributes, limitations, and potential directions for future research and development, this review aims to contribute to a comprehensive understanding of nature‐inspired algorithms in the dynamic landscape of IoT‐based healthcare services.
Predicting perceived quality of life through social trust, physical activity, and sense of happiness in Iran: Moderating role of gender
Authors: Gilan Rajabi , Mohamadi Jamal , Zardoshtian Shirin , Sarabi Neda , Palangard Naseri , Khezeli Mehdi 
Published: May 2024

AbstractBackground and AimsIn Iran, few studies have addressed the moderating effect of gender on determinants of quality of life. This study aimed to determine the effect of social trust, physical activity, and sense of happiness on the perceived quality of life, considering the moderating role of gender.MethodsThis was a population‐based cross‐sectional study. The statistical population were men and women aged 16 years and above in five western provinces of Iran. The final sample size was estimated to be 1268 people calculated through the correlation coefficient estimation formula, and finally 1185 questionnaires received. Data were analyzed using SPSS and AMOS software.ResultsThe mean score of quality of life among women was significantly higher than that of men (p < 0.001). The direct standardized coefficient showed that the sense of happiness (β = 0.40), social trust (β = 0.20), and physical activity (β = 0.12) had a significant effect on the perceived quality of life (p < 0.001). Also, gender had a moderating role in the relationship between sense of happiness and perceived quality of life (z‐score = 3.246, p < 0.001). Totally, 21% of the changes in perceived quality of life were explained by three main variables. The main variables were stronger explanatory factors in men (R = 0.26) than in women (R = 0.17).ConclusionsThe final model showed that sense of happiness had the most direct effect on the perceived quality of life, moderated by gender. Considering that the quality of life among men was lower than that among women and the direct effect of happiness on quality of life was more among men than that among women, it is suggested that gender‐based health promotion interventions with an emphasis on men be carried out to strengthen the sources of happiness to improve quality of life.
Fragmentomics features of ovarian cancer
Authors: Chao Xiaopei , Kai Zhentian , Wu Huanwen , Wang Jing , Chen Xiaojing , Su Haiqi , Shang Xiao , Lin Ruijue , Huang Lisha , He Hongsheng , Lang Jinghe , Li Lei 
Published: May 2024

AbstractOvarian cancer (OC) is a major cause of cancer mortality in women worldwide. Due to the occult onset of OC, its nonspecific clinical symptoms in the early phase, and a lack of effective early diagnostic tools, most OC patients are diagnosed at an advanced stage. In this study, shallow whole‐genome sequencing was utilized to characterize fragmentomics features of circulating tumor DNA (ctDNA) in OC patients. By applying a machine learning model, multiclass fragmentomics data achieved a mean area under the curve (AUC) of 0.97 (95% CI 0.962–0.976) for diagnosing OC. OC scores derived from this model strongly correlated with the disease stage. Further comparative analysis of OC scores illustrated that the fragmentomics‐based technology provided additional clinical benefits over the traditional serum biomarkers cancer antigen 125 (CA125) and the Risk of Ovarian Malignancy Algorithm (ROMA) index. In conclusion, fragmentomics features in ctDNA are potential biomarkers for the accurate diagnosis of OC.
The exploration of cell population data in clinical use: Beyond infectious diseases
Authors: Huang Shayuanzi , Liu Yin , Qian Liu , Zhou Juan , Wang Dong 
Published: May 2024

AbstractCell population data (CPD) is regarded as the fingerprint of a blood cell at a given moment. CPD parameters harbor information associated with cell morphology and can be automatically generated using modern hematological analyzers. Various studies have revealed many unique clinical applications for CPD, especially for infectious diseases, such as sepsis. For example, one monocyte‐related CPD parameter is the monocyte distribution width (MDW), which can be generated using a Beckman Coulter hematological analyzer. MDW has received FDA and CE approval for aiding in sepsis diagnosis in adult patients in the emergency department. Additionally, MDW can serve as a diagnostic biomarker in patients infected with SARS‐CoV‐2. CPD has also been widely explored for possible clinical applications beyond infectious diseases, such as for predicting myelodysplastic syndromes, screening for hematological malignancies, and detecting sterile inflammation. CPD parameter measurements are easily obtained and quite cost‐effective, making them practical for clinical use. However, there are some potential drawbacks of CPD parameters. Some pre‐analytical conditions can affect CPD values. Furthermore, CPD are specific to certain hematological analyzers and the result cannot be transferred between different analyzers. The practical usefulness of CPD reference intervals is also still questionable. In this review, wesummarize the current studies related to CPD and its clinical applications. Additional well‐designed clinical studies related to CPD are still expected.
Survey of patient satisfaction with genetic counseling services in Korea
Authors: Choi In Hee , Kim Yun Kyung , Yang Seo Yeon , Choi Vit‐Na , Ji Su Min , Kim Jun Young , Lee Beom Hee 
Published: May 2024

AbstractSince the 1990s, genetic clinics have been established in South Korea, enabling the provision of clinical genetics services. However, genetic counseling services are not widely used in the medical system. In contrast, recently, the demand for genetic counseling has increased due to the rapid development of genomic medicine. Therefore, it is important for medical geneticists and genetic counselors to collaboratively provide genetic counseling services. This study aimed to evaluate the perception and satisfaction of patients with rare genetic diseases and their families regarding genetic counseling services provided by a genetics team at the medical genetics center of a tertiary general hospital for rare genetic diseases. From April to November 2021, a survey was conducted with 203 individuals, including 111 and 92 individuals in the patient and family groups, respectively. Overall, 164 individuals (80.8%) responded that they were aware of genetic counseling services, and 135 individuals (66.5%) responded that they were aware of the role of genetic counselors. Patients and their families wanted to receive information about the following from genetic counseling: clinical manifestation and prognosis of the diagnosed disease (78.8%), treatment and management of the disease (60.6%), risk of recurrence within the family (55.7%), treatment options and alternatives for family and prenatal testing, and various support services. The score of satisfaction with genetic counseling services provided by the genetics team was 8.19 ± 1.68 out of 10. Patients with rare genetic diseases and their families were satisfied with genetic counseling services regarding their diseases, test results, and treatment options. Moreover, the patients could receive psychosocial support and referrals to other medical service providers and support services. As a genetic team approach, collaboration between medical geneticists and certified genetic counselors would be useful in providing information and in diagnosing, treating, and managing patients.
2‐Vinylaniline in the synthesis of heterocycles: Recent advances
Authors: Doraghi Fatemeh , Navid Hamed , Karimian Somaye , Larijani Bagher , Mahdavi Mohammad 
Published: May 2024

Abstract2‐Vinylanilines are readily accessible substrates, which are undoubtedly one of the best candidates for the construction of diversely nitrogen‐containing heterocyclic compounds. Owing to the amine and alkenyl groups in their structures, these frameworks offer a facile, direct, and selective synthetic method. This review describes various cyclization reactions involving 2‐vinylanilines catalyzed by transition metals, or under metal‐free conditions.
Performance assessment of portable Raman spectroscopy in determining ecstasy tablets
Authors: Ng Choon Hiang , Kunalan Vanitha , Yew Chong Hooi , Chang Kah Haw , Abdullah Ahmad Fahmi Lim 
Published: May 2024

AbstractEcstasy tablets, a type of common street drug originally consisting of 3,4‐methylenedioxymethamphetamine (MDMA), provide stimulant and hallucinogen psychoactive effects. They are frequently found in nightclubs, musical festivals or other recreational events believed to create a relaxing experience for the users. From a forensic perspective, when the drug of abuse is suspected in such scenarios, the law enforcement personnel would then require an easy‐to‐perform, quick and accurate method to detect the existence of such controlled substance prior to the seizure and subsequent forensic examination. In this study, we assessed the performance of a portable Raman spectroscopy as the primary aid in determining ecstasy tablets at the point of use. A total of 130 ecstasy tablet samples were analysed by Raman spectroscopy and characterised by gas chromatography–mass spectrometry (GC–MS). Active chemical substances and cutting agents detected by the two instrumentations were then compared. The performance of Raman spectroscopy was further assessed in terms of its accuracy, sensitivity and specificity, corresponding to the analysis results obtained from GC–MS analysis. Overall, portable Raman Spectroscopy used in this study shows an accuracy of 85.4% in analysing ecstasy tablets obtained from case samples, while the sensitivity and specificity were determined as 85.2% and 100%, respectively. No false positives for MDMA or other drugs were reported. Our results show that portable Raman spectroscopy is a suitable technique for targeted determination of the presence of ecstasy tablets, especially in forensic cases that require non‐destructive, rapid and mass screening during on‐site testing by law enforcement personnel.
Facile Characterization of Isothermal Crystallization and Microphase Separation Kinetics of Polyamide 6 (PA6)‐Based Thermoplastic Elastomers
Authors: Yuan Ruchao , Zhang Longfeng , Zhang Junfeng , Wang Xueli , Yu Jianyong , Li Faxue 
Published: May 2024

AbstractThe facile characterization of isothermal microphase separation kinetics in polyamide 6 (PA6)‐based thermoplastic elastomers (TPAE‐6) has long posed a challenge for the development of suitable melt spinning processes. In this study, this challenge is addressed through differential scanning calorimetry (DSC) measurements. It is assumed that the enthalpy changes of TPAE‐6 during the isothermal process are a linear superposition of enthalpy changes associated with microphase separation and crystallization of PA6 in hard phases, resembling that of TPAE‐6 without soft segments (TPAE‐6‐0). The study reveals that, as the concentration of soft segments in TPAE‐6 increases, the accelerated dynamics of phase separation become stronger than the dilution of soft segments to PA6 segments during isothermal process, resulting in an increase in the microphase separation rate of TPAE‐6. Furthermore, despite microphase separation, the overall crystallization rate of TPAE‐6 decreases with rising isothermal temperature and varies with increasing soft segment content at different temperatures. Additionally, the crystallization mode of TPAE‐6 follows two‐dimensional, three‐dimensional, or a combination of both crystal growth mechanisms, accompanied by a heterogeneous nucleation mechanism.
Exploring the influence of fintech patents on operation efficiency and market efficiency in Taiwan's commercial banking sector‐meta entropy dynamic two‐stage DDF model
Authors: Lee Sin , Chang Tzu‐Han , Chiu Yung‐ho 
Published: May 2024

AbstractThis paper presents a meta entropy dynamic two‐stage DDF model, incorporating significant patents in financial technology (fintech) into the analysis to examine the operational and market efficiencies of banks in Taiwan, providing new insights for research on banking performance and government policy. The results show the following. (1) The most efficient bank is Cathay Financial, while the bottom three are First Financial, E.SUN Financial, and Hua Nan Financial. (2) Financial holding companies (FHCs) outperform non‐FHCs in both operational and market stages. (3) The number of patents has a positive impact on the market stage efficiency of banks.
Toward a multi‐layer micro‐structured detector for high‐energy electron radiotherapy
Authors: Brivio Davide , Liles Arianna , Gagne Matthew , Sajo Erno , Zygmanski Piotr 
Published: May 2024

AbstractBackgroundThe use of electron beams has been rekindled by the advent of ultra‐high‐dose rate radiotherapy (FLASH) and very high energy electrons (VHEE). The need for development of novel technology for beam monitoring and dosimetry of such beams is of paramount importance prior to their clinical translation.PurposeIn this work we explore the potential of a multi‐layer nanoporous aerogel High‐Energy‐Current (HEC) detector as a dosimeter for electron beam. The detector does not suffer from radiation damage or signal saturation, making it suitable for very‐high‐dose‐rate applications. Standard dose rates and energies are used to establish reference for FLASH and VHEE. We explore detector response to electron energy and residual range both experimentally and computationally.MethodsMultilayer HEC detectors were constructed using 1×–10× basic modules of Aluminum(Al)_aerogel(A)_Tantalum(Ta) with 10–70 µm layer thicknesses. Signals are collected from all electrodes (3–21, depending on module multiplicity) with zero external voltage bias. Measurements are acquired as a function of depth(z) in water equivalent plastic using Varian TrueBeam for energies E = 6,9,12,15 MeV (SAD = 105 cm, 6 × 6 cone, 1000 MU/min). Computational simulations of identical detector geometries are performed using the 1D deterministic code CEPXS/ONEDANT. Additionally, percent‐depth‐doses PDD(z), measured with diode in water, are used to explore the response of HEC for various energies and residual ranges.ResultsThe current measured from Ta electrodes resembles the shape of deposited charges in water and it is proportional to the derivative of the clinical PDD corrected for contribution from photon contamination. The signal is positive on the surface, and it decreases with depth reaching a negative local minimum at z = R50, before increasing again, reaching zero at about the practical range z = Rp. In contrast, the signal from Al electrodes is shaped like the electron PDD(z) shape but with lower signal at the surface and higher bremsstrahlung tail. By subtracting the signal from Ta and Al electrodes we obtained a curve resembling PDD(z,E) after Bremsstrahlung contamination correction.ConclusionsMulti‐layer HEC sensors exhibit characteristic responses to electron beams that are unlike responses of ion chambers or diodes. Since the sensor structures are sensitive to electronic disequilibrium, high‐Z electrodes give a signal proportional to the charge deposition pattern and can be modeled using the derivative of PDD(z).
Exploring the impact of inclusive leadership on proactive work behavior in nonprofit organization: The mediating role of the relational psychological contract
Authors: Rogozińska‐Pawełczyk Anna , Sudolska Agata 
Published: May 2024

AbstractThe study aims to provide empirical evidence to explain the relationship between inclusive leadership and proactive work behavior through the mediating role of the relational psychological contract in nonprofit organizations (NPOs). The data were collected from 6751 employees employed at one of the largest NPOs in Poland. The data collection was done through the Computer‐Assisted Web Interview technique. The quantitative results obtained were analyzed by structural equation modeling based on partial least squares regression. The study outlined the mechanisms through which inclusive leadership impacts employees' proactive work behavior. The evidence of a direct and positive relationship between the variables studied was intended to illuminate the role of inclusive leadership and the relational nature of the psychological contract in building proactive work behavior. In addition to the direct effects, the results of the current study add to existing evidence on the mediating role of the relational psychological contract linking inclusive leadership and proactive work behavior. Our research findings make a valuable contribution to the field of inclusive leadership and its influence on proactive work behavior among employees in the nonprofit sector. The study establishes direct and indirect connections through effective mechanisms. Its theoretical contribution refers to the approach in which a relational psychological contract has been adopted as the mediating variable in the relationship between inclusive leadership and proactive work behavior in the nonprofit sector. Moreover, the study provides managers of NPOs with important insights into how inclusive leadership can effectively motivate employees to engage in proactive work behaviors. It demonstrates that the push for diversity necessitates explicit supervisory attention in order to foster an inclusive environment in which the potential benefits of diversity can be realized.
Cluster synchronization control for the complex network with dynamic connection relations
Authors: Chen Jinbiao , Wang Yinhe , Peng Yi , Wang Xiaoxi 
Published: May 2024

AbstractIn this article, the cluster synchronization control for a complex dynamic network (CDN) with mutually coupled nodes subsystem (NS) and connection relations subsystem is investigated. The process of cluster synchronization is segmented into three dynamic continuous stages: first, the free movement, then the task‐oriented clustering, and finally the cluster synchronization. The control scheme, founded on the clustering nodes of CDN, is proposed, such that the cluster synchronization arises when clustering all the nodes into two different sub‐networks (SNs). This approach originates from the flight motion for a group of autonomous aircrafts. At a certain moment, free flight is interrupted, and all the aircrafts split into two SNs according to the given clustering rules. Then the two controlled SNs are required to achieve cluster synchronization, that is, every SN converges to the same in speed. In order to split all the nodes into two different SNs, a clustering algorithm according to the “central nodes” is proposed. Based on Lyapunov stability theory, by designing the suitable inner cluster links, the adaptive controller of NS for each SN is synthesized to guarantee the stability of the error system. It is shown that the eventual inner topology of each SN is displayed in the pre‐given form when the cluster synchronization achieves. Finally, the merits and effectiveness of the proposed control scheme are verified by a simulation example.
Development and characterization of hemp/carbon and hemp/glass hybrid and novel functionally graded hybrid composites for structural applications
Authors: Pulleti Siva Sankar , Singh Shamsher Bahadur 
Published: May 2024

AbstractThe main objective of this study is to investigate the effect of combining natural and synthetic fibers on the mechanical characteristics of hybrid and novel functionally graded hybrid composites by considering hemp as natural fiber and carbon and glass as synthetic fibers. Before manufacturing, the natural fibers were treated with sodium hydroxide (NaOH) solution to remove the impurities on the fiber surface. The fibers were reinforced in an epoxy‐based matrix using a hand‐layup technique. The volumetric fraction of the hybrid composites was 40% fibers and 60% matrix. Different types of composites, such as plain fiber reinforced polymer (FRP), sandwich hybrid (SH), alternative hybrid (AH), and functionally graded hybrid (FH), were manufactured from hybridizations of hemp/carbon and hemp/glass. In accordance with ASTM standards, the tensile, compression, flexural, short beam shear, water absorption, and wettability properties of composites were determined. FH composites with hemp fiber at the top surface had the highest improvement in tensile strength, stiffness and compressive strength compared with pure hemp FRP (HFRP) composites. Hemp SH composites had the highest improvement in flexural and short beam properties in both hybridizations compared with HFRP composites due to the stacking of synthetic fiber at the outer layers. Scanning electronic microscopic (SEM) studies identified the failure mechanism of the tensile failure specimens and also the effect of mercerization on fiber surfaces. In conclusion, this work identified the structural capacity of hybrid composites and emphasizes that FH and hemp SH composites can replace glass FRP composites in structural applications.Highlights
Treating hemp fiber with 2 g/L of NaOH for an hour had a better impact.
Functionally graded composites had better in‐plane strength and stiffness.
Composites made with synthetic fiber on the outer layers were good at bending.
In structural applications, hemp/carbon hybrid composites can replace GFRP.