bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oral Health and Oral Health Care Practices Among Low‐Income Pregnant Women
Authors: Hunter Lauren P. , Yount Susan M. 
Published: November 2011

Introduction: Access to dental care is a problem in California as in many parts of the United States. Many women, including half of those having dental problems, do not see a dentist during pregnancy. The objective of this study was to describe the oral health status and oral health practices of low‐income pregnant women in San Diego, California, and to determine the needs for oral health care education in this population. Methods: This descriptive, retrospective, correlational study examined oral health and oral health care practices by age, ethnicity, and gravidity by using medical records from a convenience sample of 380 low‐income pregnant women. Results: Most participants were primigravida, aged between 19 and 29 years, of Hispanic ethnicity, and insured by the state (Medi‐Cal). All women received education on oral health. The majority (84%) were encouraged to get a dental examination. It had been more than 1 year since the last dental visit for most women (55%). Hispanic women were in need of dental care more than Filipina women or women of other ethnicities. A broken tooth was the primary reason for immediate dental referrals. Regularity of flossing and brushing teeth differed significantly (P= .015, P < .001) across ethnic groups, with Filipina women reporting better oral care practices. Discussion: The results provide information for the future planning of effective dental health promotion programs. Findings suggest that low‐income pregnant women have some healthy oral health care practices but are in need of dental services and oral health education. An oral health history, oral health education, dental screening, and dental referral, if needed, should be a routine part of prenatal care and annual examinations.
Myoendothelial Contacts, Gap Junctions, and Microdomains: Anatomical Links to Function?
Authors: SANDOW SHAUN L. , SENADHEERA SEVVANDI , BERTRAND PAUL P. , MURPHY TIMOTHY V. , TARE MARIANNE 
Published: November 2011

Please cite this paper as: Sandow SL, Senadheera S, Bertrand PP, Murphy TV, Tare M. Myoendothelial contacts, gap junctions, and microdomains: anatomical links to function? Microcirculation 19: 403‐415, 2012.AbstractIn several species and in many vascular beds, ultrastructural studies describe close contact sites between the endothelium and smooth muscle of <∼20 nm. Such sites are thought to facilitate the local action of signaling molecules and/or the passage of current, as metabolic and electrical coupling conduits between the arterial endothelium and smooth muscle. These sites have the potential for bidirectional communication between the endothelium and smooth muscle, as a key pathway for coordinating vascular function. The aim of this brief review is to summarize the literature on the ultrastructural anatomy and distribution of key components of MECC sites in arteries. In addition to their traditional role of facilitating electrical coupling between the two cell layers, data on the role of MECC sites in arteries, as signaling microdomains involving a spatial localization of channels, receptors and calcium stores are highlighted. Diversity in the density and specific characteristics of MECC sites as signaling microdomains suggests considerable potential for functional diversity within and between arteries in health and disease.
Foot‐and‐mouth disease and the Mexican cattle industry
Authors: Nogueira Lia , Marsh Thomas L. , Tozer Peter R. , Peel Derrell 
Published: November 2011

AbstractThe objective of this article is to analyze the domestic and international effects of a hypothetical foot‐and‐mouth disease (FMD) outbreak in the Mexican cattle industry. A discrete time dynamic optimization model of the Mexican cattle sector is specified, and linked to domestic and international markets. Economic consequences of FMD outbreaks are simulated over time and under different scenarios. Specific findings and general policy recommendations are provided. The study reports a range of outbreaks from localized to large scale and suggests that changes in economic surplus due to FMD range from a positive net gain of $0.89 to $1.6 billion to a net loss of about $67 billion, depending on the specific mitigation strategy and outbreak scenario.
A prospective study on implants installed with flapless‐guided surgery using the all‐on‐four concept in the mandible
Authors: Landázuri‐Del Barrio R. A. , Cosyn J. , De Paula W. N. , De Bruyn H. , Marcantonio E. 
Published: November 2011

AbstractAimClinical data are scarce on flapless‐guided surgery in the mandible using the all‐on‐four concept. In addition, limited documentation exists on the latter under immediate loading conditions with a pre‐fabricated implant bridge. The aim was to provide detailed documentation focusing on clinical and radiographic outcome and complications.Material and methodsSixteen systemically healthy non‐smoking patients (10 women, 6 men, average age 59 years) with sufficient bone volume in the mandible were operated via flapless‐guided surgery using the all‐on‐four concept. Clinical and radiographic data and complications were registered at 3, 6 and 12 months.ResultsThe overall implant survival rate was 90% with a trend for higher failure of short implants (P = 0.098). The mean bone level after 12 months of function was 0.83 mm with a maximum of 1.07 mm. Technical complications were common (15/16 patients). These mainly related to a misfit between the pre‐fabricated prosthesis and abutment(s) (13/16 patients).ConclusionIf immediate loading of implants is pursued fabrication of the implant bridge should be based on actual impression of the implants at the time of surgery and not on their virtual position.
Growth Inhibition of Foodborne Pathogens by Oenococcus oeni
Authors: Chiang I‐Yuan , Worobo Randy W. , Churey John J. , Henick‐Kling Thomas 
Published: November 2011

Abstract:  To explore the possibility of using Oenococcus oeni to inhibit foodborne pathogens, and to characterize antimicrobial compounds produced by O. oeni, 24 strains of O. oeni were tested for their ability to inhibit growth of foodborne pathogens, Escherichia coli O157:H7, Salmonella enteritidis, and Listeria monocytogenes by using the spot‐on‐lawn method. Of the 24 strains, 17 strains were able to inhibit all 3 pathogens in this study. Proteases, catalase, and buffer solutions were used for determining the type of inhibitory compounds produced from 4 selected strains with stronger inhibitory activity. Antimicrobial activity of 2 strains against the pathogens was completely inactivated by buffer solution, and other 2 strains against E. coli O157:H7 were partially removed. The antimicrobial compound was not sensitive to selected proteases and catalase.Practical Application:  There is little information available about using O. oeni for human pathogens control. The results of this study revealed such discovery and potential applications for pathogen control.
A New Potassium Tetrabromoaurate (III)–Luminol Chemiluminescence System for the Determination of Folic Acid in Milk Powder
Authors: Zhao Shihao , Zhang Pingping , Liang Xiaohui , Hua Dongliang , Ma Tongsuo , Pei Guanglu 
Published: November 2011

Abstract:  A new chemiluminescence (CL) system based on the CL‐emitting reaction between potassium tetrabromoaurate (III) [Au(III)] and luminol in alkaline medium is described in this paper. On the basis of this study, folic acid (FA) could dramatically enhance CL intensities, and incorporated with flow injection (FI) and solid‐phase extraction (SPE), the novel CL system has been applied for the determination of FA in infant formula milk powder. Under optimum conditions, the CL intensities were linearly related to the concentration of FA in the range of 8.0 × 10−8 to 4.0 × 10−5 g/L with a correlation coefficient of 0.999, and the detection limit was 2.0 × 10−8 g/L. The relative standard deviation was 3.5% for 1.0 × 10−6g/L FA. The optimal conditions for the detection of FA were evaluated, and the interferences from some common inorganic ions and a couple of relevant organic compounds were also investigated.Practical Application:  The new Au(III)–luminol chemiluminescent system is proposed for the determination of FA; it will be an adequate technique for the analysis of low FA concentrations in pharmaceutical preparations and food samples, and it will have potential analytical applications for other substances.
Effects of Slightly Acidic Low Concentration Electrolyzed Water on Microbiological, Physicochemical, and Sensory Quality of Fresh Chicken Breast Meat
Authors: Rahman S.M.E. , Park Jiyong , Song Kyung Bin , Al‐Harbi Naif A. , Oh Deog‐Hwan 
Published: November 2011

Abstract: Anticmicrobial effect of slightly acidic low concentration electrolyzed water (SlALcEW) and strong acidic electrolyzed water (StAEW) on fresh chicken breast meat was evaluated in this study. Meat samples each of 10 ± 0.2 g in weight and 2.5 × 2.5 cm2in size were experimentally inoculated with Listeria monocytogenes (ATCC 19115) and Salmonella Typhimurium (ATCC 14028) and subjected to dipping treatment (22 ± 2 °C for 10 min) with SlALcEW and StAEW. Shelf‐life study was conducted for inoculated and noninoculated meat samples treated with SlALcEW and StAEW at storage temperatures of 5, 15, and 25 °C. Dipping treatment with electrolyzed water significantly (P < 0.05) reduced the background and inoculated pathogens compared to untreated controls. The reduction of 1.5 to 2.3 log CFU/g was achieved by SlALcEW and StAEW against background flora, L. monocytogenes and Salmonella Typhimurium. There was no significant difference (P > 0.05) between the SlALcEW and StAEW treatments efficacy. Comparing treated samples to untreated controls showed that SlALcEW and StAEW treatments extended the shelf life of chicken meat at different temperatures with marginal changes of sensory quality. Although SlALcEW and StAEW treatments showed similar antimicrobial effects but SlALcEW was more beneficial in practical application for its semineutral pH and low chlorine content.Practical Application: Food safety issues have led to development of new sanitizers to eliminate spoilage and pathogenic organisms in food. This study provides the foundation for further application of slightly acidic low concentration electrolyzed water (SlALcEW) as a sanitizing agent in meat industry. SlALcEW can be produced on site on demand and no chemicals are necessary except NaCl solution. It does not leave any residue in food due to low chlorine concentration and it is safe to handle for its semineutral pH.
Use of Autochthonous Pediococcus acidilactici and Staphylococcus vitulus Starter Cultures in the Production of “Chorizo” in 2 Different Traditional Industries
Authors: Casquete Rocío , Benito María J. , Martín Alberto , Ruiz‐Moyano Santiago , Aranda Emilio , Córdoba María G. 
Published: November 2011

Abstract:  The present study determined how the different ripening conditions affected the growth and development of 3 autochthonous starter cultures, and the physico–chemical and sensory characteristics of chorizo. Each of 3 strains of Pediococcus acidilactici (MC184, MS198, and MS200) and one of Staphylococcus vitulus (RS34) were associated to prepare the starter cultures, P184S34, P198S34, and P200S34. Then, chorizo was prepared following 2 manufacturing procedures. The autochthonous starter cultures were able to compete and colonize the sausages in both ripening procedures. The use of the starter cultures showed evident differences by the texture analysis, with the control batches being generally tougher than the starter culture batches. Also, the highest biogenic amine (BA) levels were found in control batches and the lowest in P200S34 batches. While the use of these starter cultures does not change the sensory characteristics of these traditional fermented sausages, it improves their homogeneity and safety, except for P184S34 batch in which more BAs are detected in industry 2.Practical Application:  The 3 autochthonous starter cultures selected could be used in traditional industries because they are able to compete well and colonize the dry fermented sausages “chorizo.” The use of these starter cultures improves the texture and homogeneity of traditional fermented sausages. Biogenic amines decreased in the starter cultures batches improving the safety.
Piloting a practice research network: A 12‐month evaluation of the Human Givens approach in primary care at a general medical practice
Authors: Andrews William , Twigg Elspeth , Minami Takuya , Johnson Gina 
Published: November 2011

Objective. To investigate the effectiveness of the Human Givens (HG) approach to the management of emotional distress in a primary care setting.To investigate whether or not the use of a shorter version (i.e., CORE‐10) of a well‐established psychometric instrument (i.e., Clinical Outcome in Routine Evaluation (CORE) CORE‐outcome measure, CORE‐OM) for sessional data collection is feasible for large‐scale implementation of a practice research network (PRN).Design. All clients who chose to opt into assessment for treatment with three accredited HG therapists following referral for management of psychological distress, primarily anxiety and depression, by General Medical Practitioners (GPs) or GP practice nurses working in a primary care general medical practice over a 12‐month period were included.Methods. The primary outcome measures were the CORE‐OM and CORE‐10. Pre–post effect sizes (Cohen's d) were calculated using pre, post, and pooled standard deviations to facilitate comparison with previously published studies. Mixed‐design analysis of variance (ANOVA) was used to look at differences in pre‐ and post‐treatment symptoms and potential treatment effects based on type of termination and gender. Observed intent‐to‐treat pre–post effect size using the CORE‐OM was also benchmarked against data from Clark et al. (2009) improving access to psychological therapies (IAPT) pilot site data. Results obtained using CORE‐OM were compared with those obtained using CORE‐10 to evaluate the feasibility of using the CORE‐10 for routine use in real‐world clinical settings.Results. Pre‐ to post‐treatment changes measured with the CORE‐OM and CORE‐10 suggested that the therapy was highly effective, with clients remaining in treatment to completion demonstrating the greatest benefit. Reliable change and recovery rates comparisons between the CORE‐OM and CORE‐10 indicated that the CORE‐10 is a viable alternative to the CORE‐OM. Result of the benchmarking indicated that the observed pre–post effect size was clinically equivalent to IAPT data published by Clark et al. (2009).Conclusions. Although replications are warranted as the current investigation is a pilot study, the HG approach appears to be an effective treatment. CORE‐10 is a satisfactory generic sessional assessment to use in place of the 34‐item CORE‐OM. Use of a shorter yet reliable outcome measure is likely to increase assessment completion rates. PRNs appear to be a suitable mechanism to establish treatment effectiveness across a wide range of treatments in different settings.
Proteomic Profiling of the Human Cytomegalovirus UL35 Gene Products Reveals a Role for UL35 in the DNA Repair Response
Authors: Salsman Jayme , Jagannathan Madhav , Paladino Patrick , Chan Pak-Kei , Dellaire Graham , Raught Brian , Frappier Lori 
Published: November 2011

ABSTRACTHuman cytomegalovirus infections involve the extensive modification of host cell pathways, including cell cycle control, the regulation of the DNA damage response, and averting promyelocytic leukemia (PML)-mediated antiviral responses. The UL35 gene from human cytomegalovirus is important for viral gene expression and efficient replication and encodes two proteins, UL35 and UL35a, whose mechanism of action is not well understood. Here, affinity purification coupled with mass spectrometry was used to identify previously unknown human cellular targets of UL35 and UL35a. We demonstrate that both viral proteins interact with the ubiquitin-specific protease USP7, and that UL35 expression can alter USP7 subcellular localization. In addition, UL35 (but not UL35a) was found to associate with three components of the Cul4DCAF1E3 ubiquitin ligase complex (DCAF1, DDB1, and DDA1) previously shown to be targeted by the HIV-1 Vpr protein. The coimmunoprecipitation and immunofluorescence microscopy of DCAF1 mutants revealed that the C-terminal region of DCAF1 is required for association with UL35 and mediates the dramatic relocalization of DCAF1 to UL35 nuclear bodies, which also contain conjugated ubiquitin. As previously reported for the Vpr-DCAF1 interaction, UL35 (but not UL35a) expression resulted in the accumulation of cells in the G2phase of the cell cycle, which is typical of a DNA damage response, and activated the G2checkpoint in a DCAF1-dependent manner. In addition, UL35 (but not UL35a) induced γ-H2AX and 53BP1 foci, indicating the activation of DNA damage and repair responses. Therefore, the identified interactions suggest that UL35 can contribute to viral replication through the manipulation of host responses.
Primary Percutaneous Coronary Intervention as a National Reperfusion Strategy in Patients With ST-Segment Elevation Myocardial Infarction
Authors: Terkelsen Christian J. , Jensen Lisette O. , Tilsted Hans H. , Thaysen Per , Ravkilde Jan , Johnsen Søren P. , Trautner Sven , Andersen Henning R. , Thuesen Leif , Lassen Jens F. 
Published: November 2011

Background—
In Denmark, primary percutaneous coronary intervention (PPCI) was chosen as a national reperfusion strategy for patients with ST-segment elevation myocardial infarction in 2003. This study describes the temporal implementation of PPCI in Western Denmark, the gradual introduction of field triage for PPCI (patients rerouted from the scene of the event directly to the invasive center), and the associated outcome.

Methods and Results—

The study population comprised 9514 patients treated with PPCI from 1999 to 2009 with symptom duration ≤12 hours and either a delay from the emergency medical service (EMS) call to PPCI (healthcare system delay) of ≤6 hours or as self-presenters. The median follow-up time was 3.7 years. The number of patients treated with PPCI increased from 190 in 1999 to 1212 in 2009. Among patients transported by the EMS from the scene of the event, the proportion who were field triaged directly to a PCI center increased from 33% (34/103) to 72% (616/851,
P
<0.001). Patients who were field triaged had lower long-term mortality, with adjusted hazard ratios (95% CI) of 1.26 (1.12–1.43) among patients transported by the EMS to a local hospital and then transferred, 1.28 (1.10–1.49) among patients self-presenting at a local hospital and then transferred, and 1.37 (1.18–1.58) among patients self-presenting at a PCI center.

Conclusions—
A reperfusion strategy with PPCI only for patients with ST-segment elevation myocardial infarction was successfully implemented in Western Denmark, and the majority of patients transported by the EMS are now triaged directly to the PPCI centers. This strategy is associated with lower mortality.
Roles of the Brazilian Plateau in the Formation of the SACZ
Authors: Kodama Yasu-Masa , Sagawa Tomoyuki , Ishida Sachinobu , Yoshikane Takao 
Published: November 2011

The role of the Brazilian Plateau (BP) in maintaining the South Atlantic convergence zone (SACZ) has been examined by statistical analysis and numerical experiments. Statistical analysis using 27 years of data showed that the SACZ is most intense when it is over the BP. In this case, low-level cyclonic circulation appears over the southwestern part of the BP and forms westerly flow, which intensifies low-level convergence along the SACZ with northeasterly flow from the Amazon and northerly flow along the western edge of the South Atlantic subtropical high. A vorticity budget analysis indicates that precipitation over the BP that accompanies stretching maintains the cyclonic circulation. Sensitivity experiments using a regional atmospheric model for two different cases indicate that precipitation over the BP plays a dominant role as an atmospheric heat source in maintaining the cyclonic circulation and the SACZ. In model experiments in which rain was stopped around the BP but the topography was kept, the cyclonic circulation disappeared, and the SACZ shifted southward away from its original position. In comparison with a control run, precipitation over the BP was weakened and the SACZ shifted southward in experiments in which the BP was removed or its complex, multiple-valley terrain was smoothed out. The results of this study support the ideas suggested in previous studies (i.e., that the BP has an anchor effect on the SACZ): Precipitation is intensified over the complex terrain of the BP, and mechanisms of conditional instability of the second kind occur between the precipitation over the BP and the cyclonic circulation to its southwest, which intensifies moisture convergence over the plateau.
The Mean Age of Ocean Waters Inferred from Radiocarbon Observations: Sensitivity to Surface Sources and Accounting for Mixing Histories
Authors: Gebbie Geoffrey , Huybers Peter 
Published: November 2011

Abstract
A number of previous observational studies have found that the waters of the deep Pacific Ocean have an age, or elapsed time since contact with the surface, of 700–1000 yr. Numerical models suggest ages twice as old. Here, the authors present an inverse framework to determine the mean age and its upper and lower bounds given Global Ocean Data Analysis Project (GLODAP) radiocarbon observations, and they show that the potential range of ages increases with the number of constituents or sources that are included in the analysis. The inversion requires decomposing the World Ocean into source waters, which is obtained here using the total matrix intercomparison (TMI) method at up to 2° × 2° horizontal resolution with 11 113 surface sources. The authors find that the North Pacific at 2500-m depth can be no younger than 1100 yr old, which is older than some previous observational estimates. Accounting for the broadness of surface regions where waters originate leads to a reservoir-age correction of almost 100 yr smaller than would be estimated with a two or three water-mass decomposition and explains some of the discrepancy with previous observational studies. A best estimate of mean age is also presented using the mixing history along circulation pathways. Subject to the caveats that inference of the mixing history would benefit from further observations and that radiocarbon cannot rule out the presence of extremely old waters from exotic sources, the deep North Pacific waters are 1200–1500 yr old, which is more in line with existing numerical model results.