bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Asymmetric Nozaki—Hiyama Propargylation of Aldehydes: Enhancement of Enantioselectivity by Cobalt Co‐Catalysts.
Authors: Usanov Dmitry L. , Yamamoto Hisashi 
Published: January 2011

AbstractA highly enantioselective catalytic system is developed for the asymmetric addition of propargyl bromide towards aldehydes.
ChemInform Abstract: 4‐Halogeno‐1,1,1‐trifluorobut‐3‐yn‐2‐one [4 + 2] Cycloadducts and Their Cross‐Coupling with Organozinc Compounds.
Authors: Koldobskii A. B. , Tsvetkov N. P. , Shilova O. S. , Solodova E. V. , Kalinin V. N. 
Published: January 2011

AbstractHalogenated trifluoroacetylacetylenes (I) are found to be reactive dienophiles in Diels—Alder reactions under mild conditions.
ChemInform Abstract: Cascade Palladium‐Catalyzed Direct Intramolecular Arylation/Alkene Isomerization Sequences: Synthesis of Indoles and Benzofurans.
Authors: Yagoubi Myriam , Cruz Ana C. F. , Nichols Paula L. , Elliott Richard L. , Willis Michael C. 
Published: January 2011

AbstractA series of indole and benzofuran derivatives is synthesized by a new palladium‐catalyzed intramolecular direct arylation—isomerization sequence.
ChemInform Abstract: Copper(II) Tetrafluoroborate Promoted Meinwald Rearrangement Reactions of Epoxides.
Authors: Robinson Mathew W. C. , Pillinger Kathryn S. , Mabbett Ian , Timms David A. , Graham Andrew E. 
Published: January 2011

AbstractIt is demonstrated that the copper agent functions as efficient catalyst to produce carbonyl compounds in a regioselective manner.
ChemInform Abstract: Isomerization of Electron‐Poor Alkynes to the Corresponding (E,E)‐1,3‐Dienes Using a Bifunctional Polymeric Catalyst Bearing Triphenylphosphine and Phenol Groups.
Authors: Kwong Cathy Kar‐Wing , Fu Michael Yunyi , Law Henry Chun‐Hin , Toy Patrick H. 
Published: January 2011

AbstractA non cross‐linked polystyrene bearing both phosphine and phenol groups is used as heterogenous catalyst for the stereoselective preparation of different (E,E)‐dienes and (E,E,E)‐trienes in excellent yields by isomerization of the corresponding alkynes.
ChemInform Abstract: Hofmann Rearrangement of Carboxamides Mediated by Hypervalent Iodine Species Generated in situ from Iodobenzene and Oxone: Reaction Scope and Limitations.
Authors: Zagulyaeva Aleksandra A. , Banek Christopher T. , Yusubov Mekhman S. , Zhdankin Viktor V. 
Published: January 2011

AbstractCarboxamides (I) react with in situ generated iodine(III) species and methanol to give carbamates (III) via Hofmann rearrangement.
ChemInform Abstract: 2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone‐Catalyzed Reactions Employing MnO2 as a Stoichiometric Oxidant.
Authors: Liu Lei , Floreancig Paul E. 
Published: January 2011

AbstractOxidative cyclization, dehydrogenation, ether cleavage, and cross‐dehydrogenative coupling can be carried out.
ChemInform Abstract: Arylsilanes: Application to Gold‐Catalyzed Oxyarylation of Alkenes.
Authors: Ball Liam T. , Green Michael , Lloyd‐Jones Guy C. , Russell Christopher A. 
Published: January 2011

AbstractThe dual role of Selectfluor both as an oxidant and a source of fluoride to activate the arylsilanes avoids the need of an additional activator.
ChemInform Abstract: Iridium‐Catalyzed Asymmetric Hydrogenation of Olefins Using TIQ Phosphine—Oxazoline Ligands.
Authors: Chakka Sai Kumar , Peters Byron K. , Andersson Pher G. , Maguire Glenn E. M. , Kruger Hendrik G. , Govender Thavendran 
Published: January 2011

AbstractThe title reaction affords high enantiomeric excesses but also a high substrate dependence is observed.
ChemInform Abstract: Fluorination of Bi‐ and Polycyclic Aromatic Hydrocarbons with N‐Fluorobis(phenylsulfonyl)amine in the Absence of Solvent.
Authors: Borodkin G. I. , Elanov I. R. , Shubin V. G. 
Published: January 2011

AbstractThe fluorination of a variety of arenes with N‐fluorobenzenesulfonimide under solvent‐free conditions is studied.
ChemInform Abstract: Copper‐Catalyzed Aminobromination/Elimination Process: An Efficient Access to α,β‐Unsaturated Vicinal Haloamino Ketones and Esters.
Authors: Sun Hao , Zhang Guangqian , Zhi Sanjun , Han Jianlin , Li Guigen , Pan Yi 
Published: January 2011

AbstractThe first practical halo and sulfonylamino functionalization of α,β‐unsaturated systems is easy and convenient to carry out.
ChemInform Abstract: Effective Construction of Quaternary Stereocenters by Highly Enantioselective α‐Amination of Branched Aldehydes.
Authors: Fu Ji‐Ya , Xu Xiao‐Ying , Li Yan‐Chun , Huang Qing‐Chun , Wang Li‐Xin 
Published: January 2011

AbstractChiral proline amide—thiourea bifunctional catalysts are successfully applied to the highly enantioselective amination of branched aldehydes with azadicarboxylates.
ChemInform Abstract: Palladium‐Catalyzed Amination of Unprotected Halo‐7‐azaindoles.
Authors: Henderson Jaclyn L. , McDermott Sarah M. , Buchwald Stephen L. 
Published: January 2011

AbstractOperationally simple and efficient methods are developed for the cross‐coupling of halo‐7‐azaindoles with secondary [cf.
ChemInform Abstract: An Efficient and General Synthesis of Primary Amines by Ruthenium‐Catalyzed Amination of Secondary Alcohols with Ammonia.
Authors: Imm Sebastian , Baehn Sebastian , Neubert Lorenz , Neumann Helfried , Beller Matthias 
Published: January 2011

AbstractThe homogeneously catalyzed amination of secondary and benzylic alcohols proceeds under ammonia atmosphere and Ru3(CO)12—CataCXium PCy catalysis without the need for an additional hydrogen source.
ChemInform Abstract: Efficient Platinum(II) Catalyzed Hydroformylation Reaction in Water: Unusual Product Distribution in Micellar Media.
Authors: Gottardo Marina , Scarso Alessandro , Paganelli Stefano , Strukul Giorgio 
Published: January 2011

AbstractThe hydroformylation of terminal or internal alkenes is performed by use of a surfactant that ensures dissolution of the catalyst and the substrate in water with the catalyst being positioned on the anionic surface of the micelles.
ChemInform Abstract: Palladium‐Catalyzed Carbonylative C—H Activation of Heteroarenes.
Authors: Wu Xiao‐Feng , Anbarasan Pazhamalai , Neumann Helfried , Beller Matthias 
Published: January 2011

AbstractHeteroaryl aryl ketones and di(heteroaryl) ketones are obtained from aryl iodides and various heteroarenes under optimized conditions concerning the ratios of partners and reagents, the CO pressure and the ligand.
ChemInform Abstract: Reactivity of Alkynylzirconates Towards Allyl Bromides: Selective Formation of β‐Allyl‐zirconacyclopentadienes.
Authors: Yan Xiaoyu , Zhou Yiqing , Xi Chanjuan 
Published: January 2011

AbstractReaction of alkynylzirconates with allyl bromides gives selectively β‐allylzirconacyclopentadienes [cf.
ChemInform Abstract: Enantioselective Synthesis of Cyclic, Quaternary Oxonitriles.
Authors: Guenes Yakup , Polat M. Fatih , Sahin Ertan , Fleming Fraser F. , Altundas Ramazan 
Published: January 2011

AbstractTreatment of the cyclic nitrile (I) with allylic alcohols and subsequent thermolysis allows new access to cyclic quaternary oxonitriles.
ChemInform Abstract: A Simple Method for the Preparation of Propargylamines Using Molecular Sieve Modified with Copper(II).
Authors: Fodor Anna , Kiss Arpad , Debreczeni Nora , Hell Zoltan , Gresits Ivan 
Published: January 2011

AbstractA new, heterogeneous, 4 Å molecular sieve‐supported copper(II) catalyst is developed and is used successfully in the A3coupling of aliphatic aldehydes, alkynes and secondary amines.
ChemInform Abstract: Rhodium‐Catalyzed Regioselective Amination of Secondary Allylic Trichloroacetimidates with Unactivated Aromatic Amines.
Authors: Arnold Jeffrey S. , Stone Robert F. , Nguyen Hien M. 
Published: January 2011

AbstractThe conditions allow the preparation of the structurally important motifs (45 examples) with high or (in most cases) exclusive regioselectivity.
ChemInform Abstract: Chiral Phosphoric Acid Catalyzed Enantioselective Transfer Hydrogenation of ortho‐Hydroxyaryl Alkyl N—H Ketimines.
Authors: Nguyen Thanh Binh , Bousserouel Hadjira , Wang Qian , Gueritte Francoise 
Published: January 2011

AbstractUnprotected substrates are converted in a highly efficient manner concerning yields and enantioselectivities.
ChemInform Abstract: Cooperative Catalytic Reactions Using Organocatalysts and Transition‐Metal Catalysts: Enantioselective Propargylic Alkylation of Propargylic Alcohols with Aldehydes.
Authors: Ikeda Masahiro , Miyake Yoshihiro , Nishibayashi Yoshiaki 
Published: January 2011

AbstractA thiolate‐bridged diruthenium complex and a prolinol‐derived secondary amine are used as catalysts.
ChemInform Abstract: Asymmetric Transfer Hydrogenation of Ketones Catalyzed by Rhodium Complexes Containing Amino Acid Triazole Ligands.
Authors: Tinnis Fredrik , Adolfsson Hans 
Published: January 2011

AbstractNovel L‐amino acid thioamide ligands functionalized with 1,2,3‐triazoles are prepared and used as active and selective catalysts for asymmetric reduction of ketones.
ChemInform Abstract: One‐Pot Synthesis of Optically Active Allyl Esters via Lipase—Vanadium Combo Catalysis.
Authors: Akai Shuji , Hanada Ryosuke , Fujiwara Noboru , Kita Yasuyuki , Egi Masahiro 
Published: January 2011

AbstractVanadium catalysts catalyze 1,3‐transposition of the hydroxyl group and the continuous racemization of the optically active allyl alcohols, while lipase effects the enantio‐, chemo‐, and diastereoselective esterification to achieve the dynamic kinetic resolution.
ChemInform Abstract: Highly Diastereoselective Synthesis of α‐Difluoromethyl Amines from N‐tert‐Butylsulfinyl Ketimines and Difluoromethyl Phenyl Sulfone.
Authors: Liu Jun , Hu Jinbo 
Published: January 2011

AbstractThe first efficient synthesis of α‐difluoromethyl tertiary carbinamines, α‐difluoromethyl allylic amines, and α‐difluoromethyl propargylamines through diastereoselective nucleophilic difluoromethylation with in situ generated PhSO2CF2‐ anion and an appropriate base is developed.
ChemInform Abstract: Efficient Synthesis of α‐(Fluoro/chloro/methoxy)disulfonylmethane Derivatives as Tunable Substituted Methyl Synthons via a New C—S Bond Forming Strategy.
Authors: Prakash G. K. Surya , Wang Fang , Ni Chuanfa , Thomas Tito Joe , Olah George A. 
Published: January 2011

AbstractA practical and cost‐efficient C—S bond forming strategy for the synthesis of α‐substituted disulfonylmethane derivatives (III) is developed.
ChemInform Abstract: Room‐Temperature Palladium‐Catalyzed Cross‐Coupling of Aryltrimethylammonium Triflates with Aryl Grignard Reagents.
Authors: Reeves Jonathan T. , Fandrick Daniel R. , Tan Zhulin , Song Jinhua J. , Lee Heewon , Yee Nathan K. , Senanayake Chris H. 
Published: January 2011

AbstractCompared to the most common cross‐coupling electrophiles, triflate as counterion has the highest reactivity.
ChemInform Abstract: Chiral Phosphaalkene—Oxazoline Ligands for the Palladium‐Catalyzed Asymmetric Allylic Alkylation.
Authors: Dugal‐Tessier Julien , Dake Gregory R. , Gates Derek P. 
Published: January 2011

AbstractAdducts (III) and (V) are obtained with good to excellent enantioselectivity.
ChemInform Abstract: A Facile Method for Synthesis of Polysubstituted Naphthalene Derivatives Through Pyrrolidine Catalyzed Domino Reaction.
Authors: Li Shi‐Guang , Hu Xiu‐Qin , Jia Zhen‐Xin , Xu Peng‐Fei 
Published: January 2011

AbstractNo reaction is observed in the presence of an aliphatic nitroalkene.
ChemInform Abstract: Sequential Sonogashira/Carbopalladative Cyclization/Suzuki Reactions Catalyzed by a Single Palladium Source by Using Protected Homopropargyl Alcohol.
Authors: Wang Xin , Liu Lingyan , Chang Weixing , Li Jing 
Published: January 2011

AbstractProtected homopropargyl alcohol (I) is converted into indene derivatives by a new cascade sequence including Sonogashira coupling with aryl iodides (II) or aryl bromides (V), carbopalladative cyclization and Suzuki coupling with aryl boronic acids (III).
ChemInform Abstract: One‐Pot Tandem Catalysis: A Concise Route to Fused Bicyclic Scaffolds from Acyclic β‐Ketoesters and Alkynyl Aldehydes.
Authors: Liu Lu , Wei Lai , Lu Yong , Zhang Junliang 
Published: January 2011

AbstractA rapid and highly efficient route to fused polycyclic scaffolds from simple, readily available β‐ketoesters and alkynyl aldehydes is developed as a one‐pot reaction by combining three reactions, that is, the Knoevenagel condensation, Nazarov cyclization, and Conia‐ene reactions.
ChemInform Abstract: Palladium‐Catalyzed Intermolecular Decarboxylative Coupling of 2‐Phenylbenzoic Acids with Alkynes via C—H and C—C Bond Activation.
Authors: Wang Congyang , Rakshit Souvik , Glorius Frank 
Published: January 2011

AbstractThe annulation of 2‐phenylbenzoic acids with aromatic alkynes can also be applied to the synthesis of polycyclic aromatic hydrocarbons for material science.
ChemInform Abstract: Novel Method for Synthesizing Spiro[4.5]cyclohexadienones Through a Pd‐Catalyzed Intramolecular ipso‐Friedel—Crafts Allylic Alkylation of Phenols.
Authors: Nemoto Tetsuhiro , Ishige Yuta , Yoshida Mariko , Ohno Yuta , Kanematsu Mutsumi , Hamada Yasumasa 
Published: January 2011

AbstractThe reaction is mostly successfull using PPh3 as a co‐catalyst.
ChemInform Abstract: Trimethylsilyldiazomethane as a Versatile Stitching Agent for the Introduction of Aziridines into Functionalized Organic Molecules.
Authors: Ren Hong , Wulff William D. 
Published: January 2011

AbstractAcylation of trimethylsilyldiazomethane with aliphatic acid chlorides is coupled with the catalytic asymmetric aziridination of aldimines with a chiral polyborate Broensted acid catalyst, derived from the biaryl ligands VAPOL and VANOL.
ChemInform Abstract: Vinylogous Mukaiyama—Michael Reactions Between 2‐Silyloxyfurans and Cyclic Enones or Unsaturated Oxo Esters.
Authors: Chabaud Laurent , Jousseaume Thierry , Retailleau Pascal , Guillou Catherine 
Published: January 2011

AbstractIn the presence of SnCl4, cyclic enones and silyloxyfurans (II) undergo vinylogous Mukaiyama—Michael reactions to afford γ‐butenolides preferentially with anti stereoselectivity.
ChemInform Abstract: Ruthenium‐Catalyzed Tandem Ring‐Opening/Ring‐Closing/Cross‐Metathesis of 1,6‐Cyclopropene‐ynes and Olefins for the Construction of the 3‐Pyrroline Skeleton.
Authors: Zhu Zhi‐Bin , Shi Min 
Published: January 2011

AbstractIn the presence of first generation Grubbs′ catalyst, highly functionalized 3‐pyrroline derivatives and furan analogues (IX)/(X) are available.
ChemInform Abstract: Hg(OTf)2—BINAPHANE‐Catalyzed Enantioselective Anilino Sulfonamide Allyl Alcohol Cyclization.
Authors: Yamamoto Hirofumi , Ho Elisabeth , Namba Kosuke , Imagawa Hiroshi , Nishizawa Mugio 
Published: January 2011

AbstractThe present method is useful for syntheses of various indoline derivatives, which are important structural units for drug development.
ChemInform Abstract: “On‐Water”, Microwave‐Assisted, Pd‐Catalyzed Synthesis of Indoles from Imines and o‐Difunctionalized Arenes.
Authors: Barluenga Jose , Jimenez‐Aquino Agustin , Aznar Fernando , Valdes Carlos 
Published: January 2011

AbstractThe results show that reactions in water under microwave irradiation provide comparable results, in terms of generality and yield, to the thermal process in an organic solvent as previously described.
ChemInform Abstract: Gold‐Catalyzed Annulations of 1‐(2,3‐Butadienyl)‐1H‐indole Derivatives.
Authors: Barluenga Jose , Piedrafita Maria , Ballesteros Alfredo , Suarez‐Sobrino Angel L. , Gonzalez Jose M. 
Published: January 2011

AbstractThe gold‐catalyzed cycloisomerization of N‐tethered allenylindoles which tolerates additional functional groups is reported.
ChemInform Abstract: Zn/C‐Catalyzed Cycloaddition of Azides and Aryl Alkynes.
Authors: Meng Xu , Xu Xiaoqun , Gao Tingting , Chen Baohua 
Published: January 2011

AbstractCharcoal impregnated with zinc is used as an efficient heterogeneous catalyst for the cycloaddition of organic azides with aromatic alkynes providing 1,2,3‐triazoles.
ChemInform Abstract: General Solution to the Synthesis of N‐2‐Substituted 1,2,3‐Triazoles.
Authors: Wang Xiao‐jun , Zhang Li , Krishnamurthy Dhileepkumar , Senanayake Chris H. , Wipf Peter 
Published: January 2011

AbstractThe regioselectivity in the N‐alkylation of 4,5‐disubstituted substrates is investigated.
ChemInform Abstract: The Organocatalytic Two‐Step Synthesis of Diversely Functionalized Tricyclic Tetrazoles.
Authors: Huang Xiong , Li Ping , Li Xin‐Sheng , Xu Dong‐Cheng , Xie Jian‐Wu 
Published: January 2011

AbstractA simple method for the synthesis of diversely functionalized tricyclic tetrazoles from functionalized α,β‐unsaturated ketones and malononitrile is described.
ChemInform Abstract: Novel Fluoro‐Substituted Benzo‐ and Benzothieno Fused Pyrano[2,3‐c]pyrazol‐4(1H)‐ones.
Authors: Holzer Wolfgang , Ebner Angelika , Schalle Karin , Batezila Gyselle , Eller Gernot A. 
Published: January 2011

AbstractA straightforward two‐step synthesis of title compounds (IV) and (IX) and their NMR data are given.
ChemInform Abstract: Piperidine‐Based Renin Inhibitors: Upper Chain Optimization.
Authors: Benzencon Olivier , et al. et al. 
Published: January 2011

AbstractThe optimization of the C‐4 position of 3,4‐disubstituted piperidine‐based renin inhibitors leads to the discovery of compound (I) (ACT‐178882, MK‐1597), a renin inhibitor with a suitable profile for development.
ChemInform Abstract: Facile Synthesis of 2,4‐Diamino‐6‐alkyl‐ or 6‐Aryl‐pyrimidine Derivatives.
Authors: Wang Xihong , Sathunuru Ramadas , Melendez Victor , Kozar Michael P. , Lin Ai J. 
Published: January 2011

AbstractTwo different approaches to 6‐substituted 2,4‐diaminopyrimidines are compared.
ChemInform Abstract: Stereodivergent Synthesis of 1,3‐syn‐ and anti‐Tetrahydropyrimidinones.
Authors: Morgen Michael , Bretzke Sebastian , Li Pengfei , Menche Dirk 
Published: January 2011

AbstractDepending on the choice of solvent either syn‐ or anti‐diastereomers can be obtained as protected 1,3‐diamine structures.
ChemInform Abstract: Synthesis of New Sulfur‐Linked 1,2,4‐Triazolothienopyrimidine and 1,2,4‐Triazolopyrazolopyrimidine Derivatives Containing Fused Heterocyclic Pyrimidines.
Authors: Song Yang‐Heon , Son Hoon Young 
Published: January 2011

AbstractSimilar reactions are carried out starting from the corresponding hydrazines linked to thieno[2,3‐e]pyrimidine and pyrazolo[4,3‐e]pyrimidine analogues.
ChemInform Abstract: Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones by Three‐Component Coupling of Isatoic Anyhdride, Amines, and Aldehydes Catalyzed by Magnetic Fe3O4 Nanoparticles in Water.
Authors: Zhang Zhan‐Hui , Lue Hong‐Yan , Yang Shu‐Hong , Gao Jian‐Wu 
Published: January 2011

AbstractAn efficient one‐pot procedure is developed for the synthesis of the title compounds (IV), (VI), and (VII).
ChemInform Abstract: Synthesis, Antimicrobial, and Mosquito Larvicidal Activity of 1‐Aryl‐4‐methyl‐3,6‐bis‐ (5‐methylisoxazol‐3‐yl)‐2‐thioxo‐2,3,6,10b‐tetrahydro‐1H‐pyrimido [5,4‐c]quinolin‐5‐ones.
Authors: Rajanarendar E. , Reddy M. Nagi , Murthy K. Rama , Reddy K. Govardhan , Raju S. , Srinivas M. , Praveen B. , Rao M. Srinivasa 
Published: January 2011

Abstract8 Title compounds of type (VI) are prepared and evaluated for their antimicrobial and mosquito larvicidal activities.
ChemInform Abstract: A Practical and Stereoselective Synthesis of (+/‐)‐trans‐4‐Benzyloctahydropyrrolo[3,4‐b][1,4]oxazine.
Authors: Walker Daniel P. , Strohbach Joseph W. , McGlynn Molly A. , Lu Hwang‐Fun 
Published: January 2011

AbstractStarting from commercially available cis‐epoxysuccinic acid (I) a facile stereoselective synthesis of title compound (V) is described.
ChemInform Abstract: Asymmetric Allylic Alkylation in Combination with Ring‐Closing Metathesis for the Preparation of Chiral N‐Heterocycles.
Authors: Teichert Johannes F. , Zhang Suyan , van Zijl Anthoni W. , Slaa Jan Willem , Minnaard Adriaan J. , Feringa Ben L. 
Published: January 2011

AbstractChiral six‐ to eight membered N‐heterocycles are synthesized via the two‐step sequence.
ChemInform Abstract: One‐Pot Synthesis of 4,6,8‐Trinitro‐4,5,7,8‐tetrahydro‐6H‐furazano[3,4‐f]‐1,3,5‐triazine in Ionic Liquids.
Authors: Sheremetev Aleksei B. , Aleksandrova Natal'ya S. , Suponitsky Kyrill Yu. , Antipin Mikhail Yu. , Tartakovsky Vladimir A. 
Published: January 2011

AbstractOptimum reaction conditions are examined for the formation of the trinitro triazepine derivative (III).
ChemInform Abstract: Asymmetric Cyanosilylation of Ketones Catalyzed by Recyclable Polymer‐Supported Copper(II) Salen Complexes.
Authors: Rajagopal Gurusamy , Selvaraj Shanmugam , Dhahagani Karuthamohamed 
Published: January 2011

AbstractThe application of soluble and insoluble polymer‐supported Cu(salen) complexes as catalysts in asymmetric cyanosilylation reactions is reported.
ChemInform Abstract: Arenediazonium Tetrafluoroborates in Palladium‐Catalyzed C—P Bond‐Forming Reactions. Synthesis of Arylphosphonates, ‐phosphine Oxides, and ‐phosphines.
Authors: Berrino Roberta , Cacchi Sandro , Fabrizi Giancarlo , Goggiamani Antonella , Stabile Paolo 
Published: January 2011

AbstractA palladium‐catalyzed synthesis of aryl—P derivatives from arenediazonium tetrafluoroborates is developed that can be performed as a one‐pot process from anilines.
ChemInform Abstract: Palladium‐Catalyzed Propargylic Substitution with Phosphorus Nucleophiles: Efficient, Stereoselective Synthesis of Allenylphosphonates and Related Compounds.
Authors: Kalek Marcin , Johansson Tommy , Jezowska Martina , Stawinski Jacek 
Published: January 2011

AbstractWith exception of substrate (X), the process affords the desired products.
ChemInform Abstract: A Novel Arylethynyltriazole Acyclonucleoside Inhibits Proliferation of Drug‐Resistant Pancreatic Cancer Cells.
Authors: Wang Menghua , Xia Yi , Fan Yuting , Rocci Palma , Qu Fangi , Iovanna Juan L. , Peng Ling 
Published: January 2011

Abstract10 Novel ethynyltriazole acyclonucleosides of type (III) are prepared and evaluated for their anticancer activities on drug‐resistant pancreatic cancer MiaPaCa‐2 cells.
ChemInform Abstract: Substituted 4‐Amino‐1H‐pyrazolo[3,4‐d]pyrimidines as Multi‐targeted Inhibitors of Insulin‐Like Growth Factor‐1 Receptor (IGF1R) and Members of ErbB‐Family Receptor Kinases.
Authors: Wang Gary T. , et al. et al. 
Published: January 2011

AbstractA series of title compounds is shown to be potent inhibitors of IGF1R, EGFR, and ErbB2 receptor kinases with compound (I) giving the best results.
ChemInform Abstract: In‐situ Scanning Transmission X‐Ray Microscopy of Catalytic Solids and Related Nanomaterials
Authors: de Groot Frank M. F. , de Smit Emiel , van Schooneveld Matti M. , Aramburo Luis R. , Weckhuysen Bert M. 
Published: January 2011

AbstractReview: 74 refs.
Head‐to‐Tail Intermolecular Hydrogen Bonding of OH and NH Groups with Fluoride
Authors: Ashokkumar Pichandi , Ramakrishnan Vayalakkavoor T. , Ramamurthy Perumal 
Published: January 2011

AbstractTo explore the anion‐recognition ability of the phenolic hydroxyl group and the amino hydrogen, we synthesized three different acridinedione (ADD) based anion receptors, 1, 2 and 3, having OH, NH, and combination of OH and NH groups, respectively. Absorption, emission and 1H NMR spectral studies revealed that receptor 1, having only a phenolic OH group, shows selective deprotonation of the hydroxyl proton towards F−, which results in an “ON–OFF”‐type signal in the fluorescence spectral studies. Receptor 2, which only has an amino hydrogen, also shows deprotonation of the amino hydrogen with F−, whereas receptor 3 (having both OH and NH groups) shows head‐to‐tail intermolecular hydrogen bonding of OH and NH groups with F− prior to deprotonation. The observation of hydrogen bonding of the OH and NH groups in a combined solution of 1 and 2 with F− in a head‐to‐tail hetero‐intermolecular fashion, and the absence of head‐to‐head and tail‐to‐tail intermolecular hydrogen bonding in 1 and 2 with F−, prove that the difference in the acidity of the OH and NH protons leads to the formation of an intermolecular hydrogen‐bonding complex with F− prior to deprotonation. The presence of this hydrogen‐bonding complex was confirmed by absorption spectroscopy, 3D emission contour studies, and 1H NMR titration.