bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decreasing incidence and mortality of lung cancer in Hungary between 2011 and 2021 revealed by robust estimates reconciling multiple data sources
Authors: Gálffy Gabriella , Szabó Géza Tamás , Tamási Lilla , Müller Veronika , Moldvay Judit , Sárosi Veronika , Kerpel-Fronius Anna , Kardos Tamás , Csada Edit , Pápai-Székely Zsolt , Szász Zoltán , Király Zsolt , Hódi Gábor , Kovács Zsuzsanna , Balogh Éva , Kovács Krisztina Andrea , Darida Miklós , Buga Viktória , Rokszin György , Abonyi-Tóth Zsolt , Kiss Zoltán , Vokó Zoltán , Bogos Krisztina 
Published: June 2024

ObjectiveHungary has repeatedly been shown to have the highest cancer-related mortality and incidence in Europe. Despite lung cancer being the most abundant malignant diagnosis in Hungary, numerous concerns have been raised recently regarding the bias inherent to reported incidence estimates. Re-analysis of reimbursement claims has been suggested previously by our group as an alternative approach, offering revised figures of lung cancer incidence between 2011 and 2016. Leveraging on this methodology, we aimed at updating Hungarian lung cancer incidence estimates with an additional 5 years (2017–2021), including years affected by the COVID-19 pandemic. Additionally, we also attempted to improve the robustness of estimates by taking additional characteristics of the patient pathway into account.MethodsLung cancer patients between 2011 and 2021 were identified based on reimbursement-associated ICD-10 codes, histology codes and time patterns. Multiple query architectures were tested for sensitivity and compared to official estimates of the Hungarian National Cancer Registry (HNCR). Epidemiological trends were estimated by Poisson-regression, corrected for age and sex.ResultsA total of 89,948 lung cancer patients diagnosed in Hungary between 2011 and 2021 have been identified by our study. In 2019 alone, 7,887 patients were diagnosed according to our optimized query. ESP2013 standardized rate was estimated between 92.5/100,000 (2011) and 78.4/100,000 (2019). In 2019, standardized incidence was 106.8/100,000 for men and 59.7/100,000 for women. Up until the COVID-19 pandemic, lung cancer incidence was decreasing by 3.18% (2.1%–4.3%) yearly in men, while there was no significant decrease in women. Young age groups (40–49 and 50–59) featured the largest improvement, but women aged 60–79 are at an increasing risk for developing lung cancer. The COVID-19 pandemic resulted in a statistically significant decrease in lung cancer incidence, especially in the 50–59 age group (both sexes).ConclusionOur results show that using an optimized approach, re-analysis of reimbursement claims yields robust estimates of lung cancer incidence. According to this approach, the incidence rate of male lung cancer is declining in Hungary, in concordance with the trend observed for lung cancer mortality. Among women aged 60–79, the incidence of lung cancer has risen, requiring more attention in the near future.
Theoretical study of regional potential, its essence and components
Authors: Ibragimova Z. A. 
Published: June 2024

The complex of all types of resources, capabilities and characteristics that are inherent in a particular geographical area or region is a regional potential. It covers various aspects that can affect the development and well-being of a given territorial entity in economic, social and environmental terms. It is possible to achieve effective use of the region's potential only by carrying out scientifically based actions to modify regional economic systems. The article identifies approaches to the concept of the term "regional potential" and gives the author's interpretation, considers the components of regional potential, reveals the role of regional potential in ensuring the conditions for the stability of regional economic systems.
Territory occupation sequence and population change 2005–2019 in a satellite versus core area for Grasshopper Warblers Locustella naevia
Authors: Engzell Jonas 
Published: June 2024

Because of habitat preferences and variation at a landscape level, a species’ distribution tends to show a level of aggregation. In the Grasshopper Warbler Locustella naevia, the distribution is linked to suitable breeding habitats of open grassy and herbaceous grounds, often adjacent to water. Consequently, the presence of the Grasshopper Warbler at landscape level will consist of core and satellite areas. In theory, birds can sense habitat quality and should occupy territories within those areas based on territory quality. It might also result in different population trends between different areas in the landscape. I tested these assumptions through a 15-year study in a satellite area, comparing the results to a nearby core area. In both areas, the males occupy a territory based on the perceived attractiveness, and general patterns of the territory utilization were similar between areas. Territory density was lower and the males arrived later in the satellite area, thereby confirming the satellite/core area relationship between the study areas. In the core area, no significant change in population size was noted, while in the satellite area, the population decreased significantly.
O significado da hemoglobina na correção da DLCO em mulheres pós-COVID-19
Authors: Melo Anny Caroline Souza Almeida , Menezes Victoria Carolina Luna , Melo Saulo Maia d'Avila 
Published: June 2024

Objetivos: Estimar a importância do ajuste da hemoglobina na DLCO pós-covid -19, comparar os valores de hemoglobina padrão com as dos pacientes pós-COVID-19 e determinar quantos pacientes pós-covid-19 que realizaram DLCO, estão anêmicos. Métodos: Estudo retrospectivo, observacional, realizado na Universidade Tiradentes, no período entre agosto de 2020 a junho de 2023. Incluídos indivíduos do sexo feminino, maiores de 18 anos que tiveram covid19 há mais de 30 dias dos sintomas iniciais e que realizaram provas de DLCO com dosagem da hemoglobina recente. As pacientes foram divididas em dois grupos: anemia e não anemia. Anemia foi definida quando hemoglobina ≤ 11.9 g/dl em mulheres não grávidas maiores de 15 anos e a hemoglobina padrão utilizada na DLCO foi de 13.4 g/dl no sexo feminino. A função pulmonar avaliada foi a DLCO. Feito comparação da hemoglobina da paciente com a hemoglobina padrão e comparação da DLCO ajustada pela hemoglobina com DLCO não ajustada, em ambos os grupos. Resultados: Foram selecionadas para nosso estudo 49 pacientes do sexo feminino. Destas pacientes, 10 mulheres (20,40 %) estavam anêmicas e 39 mulheres (79,60 %) não anêmicas. Houve diferenças significativas entre a hemoglobina das pacientes (grupo anemia: Hb: 10,73±1,13 g/dL e grupo sem anemia: Hb: 13,23±0,56 g/dL) versus a hemoglobina padrão: Hb:13,4 g/dL, em ambos os grupos (p ≤ 0,008 e p ≤ 0,026, respectivamente). A comparação da % DLCO ajustada pela hemoglobina das pacientes versus % DLCO não ajustada (utilizando hemoglobina padrão: 13,4 g/dL) demonstrou diferenças significativas, em ambos os grupos (grupo anemia: % DLCO: 64,20±16,69 x % DLCO-Hb: 70,60±18,87; p ≤ 0,005 e grupo não anemia: % DLCO: 79,79±17,67 x % DLCO-Hb: 80,41 ±18,06; p ≤ 0,007). Conclusões: demonstramos uma prevalência de 20,40 % de anemia no pós-covid-19 em mulheres que realizaram DLCO, evidenciamos que existe diferenças significativas da hemoglobina das pacientes em comparação a hemoglobina padrão e que o ajuste na dosagem da hemoglobina influencia significativamente nos resultados da DLCO em pacientes anêmicos e não anêmicos, impactando na avaliação dos resultados da DLCO.
Estratégias de prevenção e controle de infecções em unidades de terapia intensiva pediátrica
Authors: Fonseca Frederico Rosa , Matos Wander Costa , Morais Letícia Ribeiro de , Morais Wellyton Carlos Silva , Veloso Ana Paula , Sá Bruna Bezerra Torres de , Rebeschini Carlos Augusto Gomes Neto , Gonçalves Letícia Crespo , Lima Alexandra Luiza de Oliveira , Oliveira João Paulo Alves de , Varela Nicole Costa , Sousa Silvelene Carneiro de , Simi Gabriel da Cruz 
Published: June 2024

Introdução: As infecções hospitalares são um desafio global de saúde pública e geram um aumento nos custos de tratamento. Muitas dessas infecções são causadas por bactérias multirresistentes. Particularmente, as bactérias gram-negativas são notórias por sua capacidade de resistir a diversos antibióticos devido à complexidade de seu envelope celular. A emergência desses organismos resistentes destaca a necessidade crítica de desenvolver métodos de prevenção e tratamentos mais eficazes. Objetivo: Discutir as estratégias de prevenção e controle de infecções disponíveis para unidades de terapia intensiva pediátrica. Metodologia: Revisão integrativa nas bases de dados nas bases científicas: LILACS, SCIELO e PUBMED. Resultados e Discussões: 11 artigos foram selecionados. As intervenções chave incluíram: 1) meticulosa higiene das mãos, 2) emprego de técnicas assépticas durante a inserção do catéter, 3) escolha criteriosa do local de inserção, e 4) revisão periódica. Conclusão: As abordagens implementadas em Unidades de Terapia Intensiva Pediátrica para a prevenção de infecções destacam a eficácia da combinação de treinamento intensivo, técnicas de assepsia estritas e o emprego de medidas de isolamento. A adesão às diretrizes globais de saúde sublinha como práticas rigorosas de higiene e a constante vigilância são essenciais para salvaguardar pacientes em estados críticos. Estratégias como a melhoria dos sistemas de ventilação e o isolamento de pacientes com infecções ajudam a minimizar a disseminação de agentes infecciosos em ambientes intensivos.
O papel do cirurgião-dentista na manutenção de saude bucal de pacientes com síndrome de Down
Authors: Silva Neta Berenice Ferreira da , Mello Flávia Coutinho de , Silva Iasmim Lima da , Varejão Livia Coutinho , Oliveira Nayhane Cristine da Silva de , Fonseca Tiago Silva da 
Published: June 2024

A síndrome de Down (SD) é uma condição genética conhecida como trissomia do cromossomo 21. Nessa população, problemas odontológicos são comuns, como doenças periodontais, maloclusão e atraso na erupção dentária. Esses desafios exigem uma abordagem adaptada e um odontólogo capacitado para garantir a saúde bucal e o conforto do paciente. O objetivo deste estudo é analisar a importância do cirurgião-dentista na manutenção da saúde bucal desses pacientes e as dificuldades de acessibilidade aos serviços de saúde vividas por eles. Trata-se de uma revisão narrativa da literatura com realização de levantamento bibliográfico de publicações de 2005 a 2023 indexadas nas seguintes bases de dados: SciELO, Pubmed e Google Acadêmico. Os critérios de inclusão foram as publicações científicas das revistas nesta avaliação da literatura. Foram excluídos os materiais cujo texto completo não está acessível e os trabalhos que não continham questões relacionadas à higiene bucal de pessoas com síndrome de Down. Os estudos apresentaram a necessidade de adaptações, uso de tecnologias e técnicas especiais para facilitar a higiene bucal desses pacientes, bem como a importância da colaboração dos cuidadores e da participação ativa nos processos do tratamento odontológico adequado. Conclui -se que é fundamental oferecer atendimento odontológico desde cedo para garantir que as crianças se familiarizem com o ambiente odontológico, com os profissionais e desenvolvam hábitos para toda a vida.
Penerapan Komputasi Hijau Pada Data Akta Di Kantor Notaris Taufiqurrachman, S.H.
Authors: - Inayatullah - , Kamilah Nyimas Nisrinaa , Cahyani Nyimas Sabilina , Indriyani Henni 
Published: June 2024

Data merupakan aset organisasi yang sangat penting sehingga perlu dijaga keutuhannya, memiliki backup data serta mutlak dibuatkan suatu sistem untuk bisa merawatnya. Tujuan dari penelitian melakukan penerapan komputasi hijau terhadap data akta yang memiliki file penyimpan hemat memori, hemat energi, hemat biaya dan mengurangi emisi gas rumah kaca yang dapat berakibat menimbulkan pemanasan global (global warming). Batasan masalah dalam penelitian ini hanya mengenai backup data akta yang ada pada kantor Notaris Taufiqurrachman, S.H. Metode yang digunakan metode studi literatur yaitu dengan cara mempelajari teori-teori berdasarkan kajian-kajian dari jurnal-jurnal nasional dan internasional, artikel dan buku serta literatur-literatur lainnya yang didapat ada hubungannya dengan penelitian. Hasil pengujian memiliki kesimpulan, untuk melakukan backup data akta notaris dapat menggunakan file plain text (.txt) yang dapat menghemat memori, energi dalam penggunaan, hemat biaya dan mengurangi emisi gas rumah kaca CO2 sehingga dapat membantu dalam mengurangi pemanasan global (global warming).
Design of a new home-made ultrasonic extraction system
Authors: Ameer Mahdi Jaber  , Mustafa Abdulkadhim Hussein  
Published: June 2024

Innovative, sensitive, and accurate method for liquid-liquid extraction using an ultrasonic device is presented in this work. A working system was created, consisting of two basic components: the ultrasonic device and the pump device, to pump or withdraw the organic layer. a study of the key variables derived from the liquid-liquid system was carried out in the system containing Dithizone (1×10^ ̄ 3 M) in (Chloroform) CHCl₃ solvent. and aqueous copper (II) chloride(CuCl2.2H2O) (1×10^ ̄6 M) solution to determine the degree to which they affect the extraction performance attained in this manner. The effect of initial sample copper concentration and ultrasonic time, temperature effect, and pump speed, were studied, establishing the best conditions for a sample of (10 mL) aqueous solution of Cu (II) chloride, the optimum copper (II) concentration in the analyzed sample is (1×10^ ̄ 6 M), the ultrasonic time for the device is (8 min), and the flow rate of the pump is (3mL/30sec) and a temperature (27ºC) and (pH=1). The extraction degree was optimum under these conditions (96±2%) and the relative standard deviation (RSD)% (0.29%), In this work, a simple method is proposed to extract and concentrate copper in aqueous copper chloride using an ultrasonic device in the presence of dithizone solvent. The main parameters affecting the extraction method such as copper ion concentration, pump speed, temperature, device time, and the effect of equal and different volumes were evaluated. The proposed method was applied for the determination of copper in aqueous copper chloride samples. Accuracy was assessed by comparing the results with a conventional extraction method (traditional methods).
A Etnomatemática como possibilidade da decolonização nas práticas escolares do ensino da matemática
Authors: Costa Pissetti Schayla Letyelle , Do Sacramento Soares Eliana Maria , Rosa Geraldo Antônio 
Published: June 2024

Apresentamos um estudo de cunho teórico empírico, no formato de ensaio, que discorre sobre a etnomatemática e o pensamento decolonial, enfatizando que esse conceito valoriza os saberes culturais dos estudantes. Assim, a partir de algumas considerações acerca do ensino da matemática, conceituamos o programa da etnomatemática, concebido pelo professor Ubiratan D’Ambrósio, sugerindo-o como um caminho para decolonizar o ensino da matemática. Argumentamos sobre isso a partir de alguns autores e de falas do professor Ubiratan em uma entrevista concedida acerca do tema. Já a finalização ocorre por meio de reflexões sobre a relevância de decolonizar as ações escolares no ensino da matemática, tendo como inspiração as ideias e os conceitos da etnomatemática.
Marine Stability Study remote mooring devices
Authors: Данцевич И.М. , Косолап Ю.Г. , Черкасов А.В. , Лютикова М.Н. , Кравченко А.И. 
Published: June 2024

Актуальность исследования обусловлена проблематикой функционирования перегрузочных комплексов нефти с использованием выносных причальных устройств, обеспечивающих перегрузку сырья из подводных магистральных трубопроводов на танкер, используя систему гибких шлангов верхнего манифольда через поворотный стол-турель. В статье проведены исследования устойчивости и выживаемости выносных причальных устройств. В работе предложен научный подход оценки устойчивости и выживаемости плавучих терминалов по параметрам тяжения и угловым вращениям под действием возмущения системы танкер и выносное причальное устройство. В отличие от сложившейся практики расчётов по объёмному водоизмещению, устойчивость плавучего терминала по параметрам совместного влияния плавучего терминала и танкера на якорную систему под погрузкой под действием ветра и течения даёт хорошее приближение к задаче проектирования вновь создаваемых выносных причальных терминалов. В работе предложен метод исследования устойчивости морских выносных терминалов, основанный на расчёте кинетической энергии танкера с показателями присоединённых масс воды и объёмного водоизмещения. Выполнено моделирование методом конечных элементов распределения сил на якорную систему выносного причального устройства, с целью определения запаса устойчивости системы.
The relevance of the study is due to the problems of functioning of oil reloading complexes using remote mooring devices that ensure the reloading of raw materials from underwater main pipelines directly to the tanker through a system of flexible hoses of the upper manifold through a rotary table-turret. The article conducted studies of the stability and survival of remote mooring devices according to the indicators of stability and survival of remote mooring devices. The work proposes a scientific approach to assessing the stability and survival of floating terminals based on the parameters of gravity and angular rotation under the influence of disturbances in the tanker and remote mooring system. In contrast to the established practice of calculations based on volumetric displacement, the stability of a floating terminal in terms of the parameters of the joint influence of the floating terminal and tanker on the anchor system during loading under the influence of wind and current provides a good approximation to the problem of designing newly created remote mooring terminals. The paper discusses a method for calculating the fundamentals of stability of offshore marine terminals based on the calculation of the kinetic energy of a tanker with indicators of the attached masses of water and volumetric displacement. A finite element modeling of the distribution of forces on the anchor system of the remote mooring device was carried out.
Methodology for assessing the information environment based on a modified real-virtual continuum
Authors: Бурылин Я.В. , Попов А.Н. 
Published: June 2024

В статье выполнен анализ базового варианта реально-виртуального континуума, включая оценку столкновения судов при маневрировании. Произведены экспериментальные исследования в среде дополненной реальности с использованием мобильной голографической системы. В качестве экспертов были задействованы лица старшего командного состава (опыт работы в море более 10 лет) экипажей торговых судов как отечественных так и зарубежных компаний. Авторы, в сравнении с другими методами анализа аварийности, предприняли попытку адаптировать оригинальную методику «человеко-ориентированного» интерфейса для исследования влияния информационной среды на процесс принятия решения человеком-оператором (судоводителем) морской эргатической системы. Разработан модифицированный реально-виртуальный континуум. Разработан метод оценки качества восприятия в морской навигационной системе дополненной реальности. Разработана и апробирована методика оценки влияния информационной среды на скорость и качество принимаемых решений.
The article analyzes the basic version of the real-virtual continuum, including assessing the collision of ships during maneuvering. Experimental studies were carried out in an augmented reality environment using a mobile holographic system. Senior officers (more than 10 years of experience at sea) were involved as experts. The authors, in comparison with other methods of accident analysis, made an attempt to adapt the original methodology of the “human-oriented” interface to study the influence of the information environment on the decision-making process of a human operator (navigator) of a marine ergatic system. A modified real-virtual continuum has been developed. A method for assessing the quality of perception in an augmented reality marine navigation system has been developed. A methodology for assessing the influence of the information environment on the speed and quality of decisions made has been developed and tested.
Preclinical and clinical evidence of the association of colibactin-producing Escherichia coli with anxiety and depression in colon cancer
Authors: Rondepierre Fabien , Meynier Maëva , Gagniere Johan , Deneuvy Vincent , Deneuvy Anissa , Roche Gwenaelle , Baudu Elodie , Pereira Bruno , Bonnet Richard , Barnich Nicolas , Carvalho Frédéric Antonio , Pezet Denis , Bonnet Mathilde , Jalenques Isabelle 
Published: June 2024

BACKGROUND
The association between the intestinal microbiota and psychiatric disorders is becoming increasingly apparent. The gut microbiota contributes to colorectal carcinogenesis (CRC), as demonstrated with colibactin-producing Escherichia coli (CoPEC).
AIM
To evaluate the association between CoPEC prevalence and anxiety- and depressive-like behaviors with both preclinical and clinical approaches.
METHODS
Patients followed after a CRC surgery and for whom the prevalence of CoPEC has been investigated underwent a psychiatric interview. Results were compared according to the CoPEC colonization. In parallel C57BL6/J wild type mice and mice with a CRC susceptibility were chronically infected with a CoPEC strain. Their behavior was assessed using the Elevated Plus Maze test, the Forced Swimming Test and the Behavior recognition system PhenoTyper®.
RESULTS
In a limited cohort, all patients with CoPEC colonization presented with psychiatric disorders several years before cancer diagnosis, whereas only one patient (17%) without CoPEC did. This result was confirmed in C57BL6/J wild-type mice and in a CRC susceptibility mouse model (adenomatous polyposis colimultiple intestinal neoplasia/+). Mice exhibited a significant increase in anxiety- and depressive-like behaviors after chronic infection with a CoPEC strain.
CONCLUSION
This finding provides the first evidence that CoPEC infection can induce microbiota-gut-brain axis disturbances in addition to its procarcinogenic properties.
Identification of Proteus Vulgaris using Series of Biochemical Test and Staining Technique: Ecology, Pathogenicity (Enteric Pathogen), Description and Prevention of It’s Diseases
Authors: Eruchalu I Augustine  
Published: June 2024

Phenotypic identification of bacteria by staining technique and biochemical tests. This practical was carried out to identify Proteus vulgaris using biochemical test, this test includes, citrate utilization, indole, carbohydrate fermentation, methyl red, voges Proskauer, motility, production of hydrogen sulphide, catalase, and oxidase tests. Results obtained shows that Proteus vulgaris was positive to indole, motility, methyl red and urease. Proteus vulgaris was unable to utilize citrate for carbon and energy, and does not synthesis the enzyme amylase to break down starch. The bacteria fermented glucose to produce acid and gas.