bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Formation of Imines by Selective Gold‐Catalyzed Aerobic Oxidative Coupling of Alcohols and Amines under Ambient Conditions.
Authors: Kegnaes Soeren , Mielby Jerrik , Mentzel Uffe V. , Christensen Claus H. , Riisager Anders 
Published: December 2010

AbstractThe title reaction proceeds with excellent selectivity (above 98%).
ChemInform Abstract: Pd‐Catalyzed ortho‐C—H Acylation/Cross‐Coupling of Aryl Ketone O‐Methyl Oximes with Aldehydes Using tert‐Butyl Hydroperoxide as Oxidant.
Authors: Chan Chun‐Wo , Zhou Zhongyuan , Chan Albert S. C. , Yu Wing‐Yiu 
Published: December 2010

AbstractThe reaction proceeds with excellent regioselectivity to afford ortho‐arylated products.
ChemInform Abstract: Titanium(IV) Chloride Mediated Carbon—Carbon Bond‐Forming Reaction Between 3,3‐Dialkylcyclobutanones and Aldehydes.
Authors: Matsuo Jun‐ichi , Kawano Mizuki , Okuno Ryosuke , Ishibashi Hiroyuki 
Published: December 2010

AbstractThe reaction results in formation of diastereomeric mixtures of β′‐chloro‐β‐hydroxy ketones, precursors of multisubstituted cyclopentenones.
ChemInform Abstract: A New Dual Catalytic System for Asymmetric Morita—Baylis—Hillman Reaction.
Authors: Shah Jabbar , Yacob Zekarias , Bunge Alexander , Liebscher Juergen 
Published: December 2010

AbstractThe combination of a chiral guanidine catalyst and triphenylphosphine as promotor produces functionalized alcohols with up to 88% e.e.
ChemInform Abstract: Dynamic Covalent Chemistry of Disulfides Offers a Highly Efficient Synthesis of Diverse Benzofused Nitrogen—Sulfur Heterocycles in One Pot.
Authors: Zhu Ning , Zhang Fa , Liu Gang 
Published: December 2010

AbstractThe method involves a new thiol‐disulfide interchange reaction of aromatic disulfides such as (I) initiated by DBU to form thioethers in the presence of alkyl halides or Michael acceptors within seconds at room temperature, followed by cyclization under modified conditions.
ChemInform Abstract: Palladium‐Catalyzed C—F Activation of Polyfluoronitrobenzene Derivatives in Suzuki—Miyaura Coupling Reactions.
Authors: Cargill Matthew R. , Sandford Graham , Tadeusiak Andrezj J. , Yufit Dmitrii S. , Howard Judith A. K. , Kilickiran Pinar , Nelles Gabrielle 
Published: December 2010

AbstractIn the presence of KF‐Al2O3 and Pd(PPh3)4 highly fluorinated nitrobenzenes undergo efficient and regioselective coupling to new 2‐nitrobiphenyl derivatives like (III) and (V).
ChemInform Abstract: Cu‐Catalyzed Double S‐Alkenylation of Potassium Sulfide: A Highly Efficient Method for the Synthesis of Various Thiophenes.
Authors: You Wei , Yan Xiaoyu , Liao Qian , Xi Chanjuan 
Published: December 2010

AbstractA simple methodology is presented for the synthesis of di‐, tri, and tetra‐substituted derivatives (18 examples).
ChemInform Abstract: Preparation of 2,4,5‐Triarylimidazol‐4‐ols and Their Stereoselective Rearrangement by 1,5‐Phenyl Migration.
Authors: Lu Gonghao , Katoh Akira , Zhang Zhiqiang , Hu Zhizhi , Lei Peng , Kimura Masaru 
Published: December 2010

AbstractLophine hydroperoxides (I) undergo base‐triggered phenyl migration to provide the imidazolones (III) instead of amidines with chemiluminescence properties.
ChemInform Abstract: Facile Access to a Variety of 2,5‐Biaryl‐1,2,4‐triazol‐3‐ones via Regioselective N‐Arylation of Triazolones.
Authors: Park Jiyeon , Chae Junghyun 
Published: December 2010

AbstractOptimum reaction conditions and catalysts are examined for the regioselective synthesis of difficultly available 2,5‐biaryl‐1,2,4‐triazol‐3‐ones (III) from the corresponding triazolones (I).
ChemInform Abstract: Iodine‐Promoted Domino Reaction Leading to N‐Substituted 2‐Aminoquinoline‐3‐carbonitriles under Microwave Irradiation.
Authors: Jiang Bo , Li Chao , Tu Shu‐Jiang , Shi Feng 
Published: December 2010

AbstractUnder the title conditions, a highly regioselective ring‐opening/recyclization process occurs unexpectedly at the pyran ring of chromene derivatives of type (I) by treatment with isocyanates (II).
ChemInform Abstract: Synthesis and Antitumor Evaluation of a Novel Class of 4‐Substituted‐1,4‐dihydroisoquinolin‐3‐ones.
Authors: Ma Ting , Chen Wenteng , Zhang Guolin , Yu Yongping 
Published: December 2010

AbstractThe isoquinoline derivatives (18 examples) are prepared by a fully regio‐ and stereoselective intramolecular Heck reaction of amides (I).
ChemInform Abstract: Synthesis of Fused and Linked Bicyclic Nitrogen Heterocycles by Palladium‐Catalyzed Domino Cyclization of Propargyl Bromides.
Authors: Okano Akinori , Tsukamoto Koji , Kosaka Shohei , Maeda Hatsuo , Oishi Shinya , Tanaka Tetsuaki , Fujii Nobutaka , Ohno Hiroaki 
Published: December 2010

AbstractPropargyl bromides bearing nucleophilic functional groups on each terminal carbon react in the presence of sodium hydride and Pd(PPh3)4 selectively to give fused nitrogen heterocycles.
ChemInform Abstract: Copper‐Catalyzed Alkyne Cycloaddition on Electron Deficient Azides via Tetrazolo[1,5‐a]pyrimidines.
Authors: Nilsson Linda I. , Ertan Anne , Weigelt Dirk , Noelsoee Jens M. J. 
Published: December 2010

AbstractThe initially prepared tetrazolo[1,5‐a]pyrimidines (III) are capable of serving as masked azides.
ChemInform Abstract: Concise Approach Toward Tetrazolo[1,5‐a][1,4]benzodiazepines via a Novel Multicomponent Isocyanide‐Based Condensation.
Authors: Borisov Roman S. , Polyakov Anatoliy I. , Medvedeva Lidia A. , Khrustalev Victor N. , Guranova Natalia I. , Voskressensky Leonid G. 
Published: December 2010

AbstractAn efficient procedure is developed with NH4Cl is to give the target compounds in moderate yields.
ChemInform Abstract: Two New Aspidosperma Indole Alkaloids from Yunnan Kopsia arborea
Authors: Wu Yuqiu , Kitajima Mariko , Kogure Noriyuki , Wang Yunsong , Zhang Rongping , Takayama Hiromitsu 
Published: December 2010

Abstractisolation and structure elucidation of kopsiyunnanines G (I) and H (II)
ChemInform Abstract: Development of 2‐Pyrrolidinyl‐N‐methyl Pyrimidones as Potent and Orally Bioavailable HIV Integrase Inhibitors.
Authors: Ferrara Marco , Fiore Fabrizio , Summa Vincenzo , Gardelli Cristina 
Published: December 2010

AbstractAmong a series of title compounds, the derivative (I) is shown to represent a promising agent against HIV‐1 and is the subject of further studies.
ChemInform Abstract: (Cyclopentadienyl)dicarbonylmethyliron ((η5‐C5H5)Fe (CO)2CH3, FpMe), a Seminal Transition‐Metal Alkyl Complex: Mobility of the Methyl Group
Authors: Pannell Keith H. , Sharma Hemant K. 
Published: December 2010

AbstractReview: 56 refs.
Korrigendum zu: Mein kleiner grüner Kaktus
Authors: Streller Sabine , Roth Klaus 
Published: December 2010

AbstractIm “kleinen grünen Kaktus” war so richtig der Wurm drin: In Heft 4 auf S. 293 weist das C‐3 der Ribulose 5 die falsche Konfiguration auf; in unserem Korrigendum in Heft 5, S. 369 fehlt am selben C‐3 leider das Sauerstoffatom der OH‐Gruppe. Nun also hier noch einmal die Formel des Ribulose‐1,5‐biphosphats 5. Schließlich sind aller guten Dinge drei.Wir bitten um Nachsicht....
The influence of thermal treatment on color response of wood materials
Authors: Aydemir Deniz , Gunduz Gokhan , Ozden Seray 
Published: December 2010

AbstractIn this study, the influence of thermal treatment on color changes of six different wood materials was investigated. Test specimens were subjected to three different temperatures (160, 180, and 200°C) and durations (3, 5, and 7 h). The data obtained were analyzed using variance analysis, and then the statistical analysis of Tukey's test was conducted. After this treatment, the results showed that the color values of the six wood materials changed significantly. It was determined that L* (lightness) values decreased; the minimum change in L* was ∼4% for Juniper wood, and the maximum change in L* was ∼64% for Beech wood. The values of a* (red coordinate) and b* (yellow coordinate) showed varying levels of increase when the heat treatment conditions were 160°C for 3 to 7 h (not including Cherry wood), but the values began to decrease slowly after treatment at 160°C for 5 h. The ratios of the minimum and maximum color change in a* and b* were determined at 180°C for 3 h in Plane wood, 200°C for 5 h in Hazelnut wood, and 160°C for 3 h and 200°C for 7 h in Beech wood. As temperature and duration were increased, the minimum total color change (ΔE) was ∼3.5% for 160°C at 3 h in Cypress wood, and the maximum total color change (ΔE) was ∼50% for 200°C at 7 h in Cypress wood. © 2010 Wiley Periodicals, Inc. Col Res Appl, 2010
Portals for collaborative research communities: two distinguished case studies
Authors: Elsayed Ibrahim , Madey Gregory , Brezany Peter 
Published: December 2010

AbstractCase study research excels at bringing us to an understanding of a complex issue or object and can extend experience or add strength to what is already known through previous research. The research work summarized by this paper discusses two different case studies in the field of portals for collaborative research communities, in particular VectorBase and BGA‐Space. VectorBase at its core is a scientific database that focuses on search, data mining and offers multiple integrated bioinformatics tools for analyzing and browsing genomic and related data. BGA‐Space focuses on capturing semantics from scientists during processing of scientific experiments as well as preserving the full life cycle of scientific data to enable their reuse. The two case studies involve heavy research and the application of theories, concepts, and knowledge commonly discussed in the targeted field. Copyright © 2010 John Wiley & Sons, Ltd.
Abdichtung der Wienflussmauer mittels Injektionen als Hochwasserschutzmaßnahme
Authors: Pohlplatz Klaus , Krotky Kurt , Hartl Martin 
Published: December 2010

AbstractZur Herstellung der Dichtheit der Wienflusstrennmauer, welche den Hochwasserschutz der U‐Bahntrasse der Linie U4 gegenüber dem Wienfluss funktional darstellt, wurden/werden Injektionen durchgeführt. Die Gesamtlänge der zu sanierenden Mauerabschnitte beträgt 5300 m. Der Sanierungsbereich wurde in 106 Abschnitte zu 50 m Mauerlänge unterteilt. Die Injektionsarbeiten zur Hohlraumverfüllung des Mauerwerkskörpers wurden/werden zweistufig durchgeführt. Im Jahr 2009 wurden die Abschnitte C1 bis C6 saniert bzw. injiziert. Vorab waren die Injektionskriterien und Injektionsziele zu erarbeiten und verbindlich festzulegen, welche laufend u. a. mittels Wasserabpressversuchen und Bohrkernentnahmen kontrolliert bzw. überwacht werden.Sealing of the Wien river flood‐control wall by means of injections. Injections have been used to seal the flood‐control wall that separates the Wien river bed from the tracks of underground line U4. A total length of wall of 5 300 metres are in need of repair. The repair area has been divided into segments of 50 m wall length each, i.e., 106 segments. The injection works for filling voids in the wall have been carried out in two stages. In 2009, Sections C1 to C6 were repaired and injected. Before this, binding criteria for injections and injection targets had to be set, which have to be inspected and regularly monitored by means of permeability tests and core sample analysis, among other methods.
Role of morphometry in evaluation of cytologically borderline breast lesions: A study of 70 cases
Authors: Gupta Shilpa , Gupta Ruchika , Singh Sompal , Gupta Kusum , Kaur Charan Jeet 
Published: November 2010

AbstractFine needle aspiration, an accepted minimally invasive diagnostic procedure for breast masses, leads to an indeterminate (borderline) diagnosis in a significant proportion of cases. This study was aimed at evaluation of the utility of image analysis and morphometry in the cytologic assessment of borderline breast cases.A ‘study’ group of 45 cases (including fibroadenoma, fibrocystic change and ductal carcinoma) and a ‘test’ group of 25 cytologically borderline cases were included. Nuclei from each of the groups (nuclei of monolayer sheet of fibroadenoma, naked nuclei of fibroadenoma, ductal cells nuclei of fibrocystic change and nuclei of carcinoma) were manually traced and analyzed using self‐written image analysis software. Discriminant analysis was done on the ‘study’ group and the resultant discriminant functions were applied to the ‘test’ group. The percentage of nuclei correctly classified of the study as well as test group was noted.On step‐wise discriminant analysis, various morphometric, textural parameters and color information parameters were selected. Of the original ‘study’ group, 98.49% of nuclei could be correctly classified. No overlapping of benign and malignant nuclei was observed in the ‘study’ group. When the resulting functions were tested on the ‘test’ group, all the cases were correctly classified as benign or malignant (compared with the final histologic diagnosis).This study suggests that application of computerized image analysis to cytologically borderline breast cases can help in the classification of these cases as benign or malignant. This may prevent unnecessary surgery in many of these cases. Diagn. Cytopathol. 2012. © 2010 Wiley Periodicals, Inc.
Subject‐based steroid profiling and the determination of novel biomarkers for DHT and DHEA misuse in sports
Authors: Van Renterghem Pieter , Van Eenoo Peter , Sottas Pierre‐Edouard , Saugy Martial , Delbeke Frans 
Published: December 2010

AbstractDoping with natural steroids can be detected by evaluating the urinary concentrations and ratios of several endogenous steroids. Since these biomarkers of steroid doping are known to present large inter‐individual variations, monitoring of individual steroid profiles over time allows switching from population‐based towards subject‐based reference ranges for improved detection. In an Athlete Biological Passport (ABP), biomarkers data are collated throughout the athlete's sporting career and individual thresholds defined adaptively. For now, this approach has been validated on a limited number of markers of steroid doping, such as the testosterone (T) over epitestosterone (E) ratio to detect T misuse in athletes. Additional markers are required for other endogenous steroids like dihydrotestosterone (DHT) and dehydroepiandrosterone (DHEA). By combining comprehensive steroid profiles composed of 24 steroid concentrations with Bayesian inference techniques for longitudinal profiling, a selection was made for the detection of DHT and DHEA misuse. The biomarkers found were rated according to relative response, parameter stability, discriminative power, and maximal detection time. This analysis revealed DHT/E, DHT/5β‐androstane‐3α,17β‐diol and 5α‐androstane‐3α,17β‐diol/5β‐androstane‐3α,17β‐diol as best biomarkers for DHT administration and DHEA/E, 16α‐hydroxydehydroepiandrosterone/E, 7β‐hydroxydehydroepiandrosterone/E and 5β‐androstane‐3α,17β‐diol/5α‐androstane‐3α,17β‐diol for DHEA. The selected biomarkers were found suitable for individual referencing. A drastic overall increase in sensitivity was obtained.The use of multiple markers as formalized in an Athlete Steroidal Passport (ASP) can provide firm evidence of doping with endogenous steroids. Copyright © 2010 John Wiley & Sons, Ltd.
Defending Dynepo detection
Authors: Gmeiner Günter , Reichel Christian , Kulovics Ronald , Scheiblhofer Veronika 
Published: December 2010

AbstractDoping analysis as the detection of prohibited substances in an athlete's bodily specimen is not solely a scientific task; anti‐doping scientists are challenged by the athlete's experts and have to defend their results in front of arbitration panels such as the Court of Arbitration in Sports (CAS). Compliance with the internationally accepted standards issued by the World Anti‐Doping Agency (WADA) is commonly the main aspect to prove and demonstrate.Taking the example of four cases of doping with Epoetin delta (Dynepo) in endurance disciplines like marathon, triathlon, and cycling, the challenges and experiences in court and the argumentation lines of the defence experts are discussed. In all cases, doping with Epoetin delta was detected by two methods: isoelectric focusing (IEF) and SDS‐PAGE.Epoetin delta is known to be produced in a human fibrosoma cell line. The slightly more abundant bands alpha and beta result in a short detection window using IEF analysis alone. With the additional complementary information obtained by SDS‐PAGE analysis, data interpretation and defence in court is facilitated. Copyright © 2010 John Wiley & Sons, Ltd.
An ATF2‐based luciferase reporter to monitor non‐canonical Wnt signaling inxenopusembryos
Authors: Ohkawara Bisei , Niehrs Christof 
Published: December 2010

AbstractNon‐canonical/planar cell polarity (PCP) Wnt signaling plays important roles in embryonic development and tissue homeostasis, and is implicated in human disease. Monitoring Wnt/PCP signaling relies mostly on semi‐quantitative bioassays or biochemical analysis. Here we describe a luciferase reporter assay based on an ATF2 response element, which faithfully monitors non‐canonical Wnt signaling inXenopusembryos. The assay is simple, quantitative, and robust. It can be used to detect non‐canonical Wnt signaling changes following gain and loss of function of pathway components, including Wnt, Frizzled, Ror2, Disheveled, Rac1, MKK7, and JNK. Wnt/PCP signaling has recently been implicated in left‐right asymmetry and our reporter assay suggests that in gastrula embryos there is a right‐ward bias in Wnt/PCP signaling. We also mapped Wnt/PCP signaling in the earlyXenopusembryo and find that it peaks in the dorso‐vegetal region, paralleling Wnt/β‐catenin signaling. Developmental Dynamics, 2011. © 2010 Wiley‐Liss, Inc.
Hts, the Drosophila homologue of adducin, physically interacts with the transmembrane receptor golden goal to guide photoreceptor axons
Authors: Ohler Stephan , Hakeda‐Suzuki Satoko , Suzuki Takashi 
Published: December 2010

AbstractNeurons steer their axons towards their proper targets during development. Molecularly, a number of guidance receptors have been identified. The transmembrane protein Golden goal (Gogo) was reported previously to guide photoreceptor (R) axons in the Drosophila visual system. Here, we show that Hts, the Drosophila homologue of Adducin, physically interacts with Gogo's cytoplasmic domain via its head‐neck domain. hts null mutants show similar defects in R axon guidance as do gogo mutants. Rescue experiments suggest that the C‐terminal tail but not the MARCKS homology domain of Hts is required. Overexpression of either gogo or hts causes abnormally thick swellings of R8 axons in the medulla, but if both are co‐overexpressed, R8 axons appear normal and the amount of excessive Hts is reduced. Our results fit with a model where Gogo both positively and negatively regulates Hts that affects the Actin‐Spectrin cytoskeleton in growth cone filopodia, thereby guiding R axons. Developmental Dynamics, 2011. © 2010 Wiley‐Liss, Inc.
Synthesis and Characterisation of Novel (Guanidine)manganese Complexes and Their Application in the Epoxidation of 1‐Octene
Authors: Wortmann Ramona , Flörke Ulrich , Sarkar Biprajit , Umamaheshwari Venkatesan , Gescheidt Georg , Herres‐Pawlis Sonja , Henkel Gerald 
Published: December 2010

AbstractThe synthesis of manganese complexes of the guanidine–pyridine hybrid ligands DMEGqu (L1) and TMGqu (L2) is reported. The complexes [Mn2(μ‐Cl)2Cl2(DMEGqu)2] (C1), [Mn2(TMGqu)2(μ‐Cl)2Cl2] (C2), [Mn3(DMEGqu)2(μ‐CH3COO)6] (C3), [Mn3(TMGqu)2(μ‐CH3COO)6] (C4) and [Mn2(DMEGqu)2(μ‐CF3SO3)2(CF3SO3)2(H2O)2] (C5) have been structurally characterised. For C1 and C2 dinuclear chlorido‐bridged motifs have been found and trinuclear acetato‐bridged motifs for C3 and C4 which represent the first trinuclear (guanidine)manganese compounds reported so far. The dinuclear triflato complex C5 exhibits a unique Mn(μ‐CF3SO3)2(CF3SO3)2 unit. EPR measurements of C1 and C2 indicate that in solution the dinuclear complexes decompose to mononuclear species. Contrastingly, the EPR spectra of C3 and C4 show that these acetato complexes remain polynuclear in CH3CN. The chlorido and acetato complexes convince by their high stability towards air. All complexes reported herein were screened regarding their activity in the epoxidation of 1‐octene with peracetic acid. It could be proven that these compounds are able to act as catalysts in this reaction already under mild conditions. Kinetic measurements exhibit that the epoxidation reaction proceeds on a time scale interesting for industrial application.
On determining the geometric and kinematic characteristics of coherent flow structures over a gravel bed: a new approach using combined PLIF‐PIV
Authors: Hardy R.J. , Best J.L. , Parsons D.R. , Keevil G.M. 
Published: December 2010

AbstractIn gravel‐bed rivers, the microtopography of the bed is known to exert a significant influence on the generation of turbulent flow structures that owe their origin to fluid shear generated near the bed. Although field and laboratory measurements have indicated that flows over gravel beds contain a range of coherent flow structures, the kinematic and dynamic properties of these structures are still poorly understood. This paper describes a new experimental methodology to quantify simultaneously both the kinematic and dynamic characteristics of coherent flow structures based upon combined planar laser‐induced fluorescence and particle imaging velocimetry (PLIF‐PIV). The results confirm that the primary generative mechanism of coherent flow structures is at the bed, where merging hairpin vortices form around bed clasts and generate larger‐scale fluid motions that advect downstream. Copyright © 2010 John Wiley & Sons, Ltd.
Acid volatile sulfides oxidation and metals (Mn, Zn) release upon sediment resuspension: Laboratory experiment and model development
Authors: Hong Yong Seok , Kinney Kerry A , Reible Danny D 
Published: December 2010

AbstractSediment from the Anacostia River (Washington, DC, USA) was suspended in aerobic artificial river water for 14 d to investigate the dynamics of dissolved metals release and related parameters including pH, acid volatile sulfides (AVS), and dissolved/solid phase Fe2+. To better understand and predict the underlying processes, a mathematical model is developed considering oxidation of reduced species, dissolution of minerals, pH changes, and pH-dependent metals' sorption to sediment. Oxidation rate constants of elemental sulfur and zinc sulfide, and a dissolution rate constant of carbonate minerals, were adjusted to fit observations. The proposed model and parameters were then applied, without further calibration, to literature-reported experimental observations of resuspension in an acid sulfate soil collected in a coastal flood plain. The model provided a good description of the dynamics of AVS, Fe2+, S0(s), pH, dissolved carbonates concentrations, and the release of Ca(aq), Mg(aq), and Zn(aq) in both sediments. Accurate predictions of Mn(aq) release required adjustment of sorption partitioning coefficient, presumably due to the presence of Mn scavenging by phases not accounted for in the model. The oxidation of AVS (and the resulting release of sulfide-bound metals) was consistent with a two-step process, a relatively rapid AVS oxidation to elemental sulfur (S0(s)) and a slow oxidation of S0(s) to SO 42−(aq), with an associated decrease in pH from neutral to acidic conditions. This acidification was the dominant factor for the release of metals into the aqueous phase. Environ. Toxicol. Chem. 2011; 30:564–575. © 2011 SETAC