bluuebunny/crossref_metadata_2025_split huggingface dataset:
The economic basis for the implementation of anti-ranging programs in Kazakhstan
Authors: Кусаинова А.Б. , Гафурова З. 
Published: June 2024

Данная статья рассматривает экономические аспекты реализации программ антиэйнджинга в Казахстане. Авторы анализируют основные принципы и задачи антиэйнджинговых программ, а также рассматривают опыт на примере области. В статье подробно описывается механизмы и инструменты, которые могут быть использованы для борьбы с эйнджингом, а также приводятся конкретные примеры успешной реализации антиэйнджинговых программ.
his article examines the economic aspects of the implementation of anti-ranging programs in Kazakhstan. The authors analyze the basic principles and objectives of anti-ranging programs, as well as consider the experience on the example of the field. The article describes in detail the mechanisms and tools that can be used to combat ageism, as well as specific examples of successful implementation of anti-ageism programs.
Genesis of legal regulation of the sphere of public procurement and placement of orders for works and services in the Republic of Kazakhstan and abroad
Authors: Амирова М.А. 
Published: June 2024

В работе проведено исследование исторических этапов правового регулирования сферы госзакупок и размещения заказов на выполнение работ и услуг в Республике Казахстан и за рубежом. Авторами проведен анализ основополагающих нормативно-правовых актов США, ЕЭС, ЕС и РК в сфере государственных закупок, на основании чего была охарактеризована ретроспектива развития правового регулирования в данной сфере, как в РК, так и в мире в целом. Авторами отмечены положительные тенденции развития современной системы госзакупок в РК, применение современных технологий, усиление контроля со стороны государства. На основании проведенного исследования, авторами обоснованы перспективы развития отечественной системы госзакупок в ее все большей технологизации, совершенствовании системы электронных закупок, сокращении времени между этапами процесса, с целью ускорить получение необходимых товаров, работ и услуг в интересах государства и населения.
The work carried out a study of the historical legal regulation of the sphere of public procurement and the placement of orders for the performance of works and services in the Republic of Kazakhstan and abroad. The author analyzed the fundamental legal acts of the USA, EEC, EU and the Republic of Kazakhstan in the field of public procurement, on the basis of which a retrospective of the development of legal regulation in this area, both in the Republic of Kazakhstan and in the world as a whole, was characterized. The author noted positive trends in the development of the modern public procurement system in the Republic of Kazakhstan, the use of modern technologies, and increased control by the state. Based on the research, the author substantiates the prospects for the development of the domestic public procurement system in its increasing technologization, improving the electronic procurement system, reducing the time between stages of the process, in order to speed up the receipt of necessary goods, works and services in the interests of the state and the population.
Artificial intelligence – opportunities and prospects for application in higher education
Authors: Дюсембинова Ж.С. , Рамазанова К.Б. 
Published: June 2024

Актуальность данной исследовательской работы заключается в том, что в последнее время набирает популярность практическое применение искусственного интеллекта в самых разных сферах жизни людей (промышленности, медицине, финансах, торговле, маркетинге, программировании, развлечениях и даже в подборе музыки). Поэтому требуется рассмотреть все имеющиеся возможности и перспективы использования искусственного интеллекта в высшем образовании Республики Казахстан, дабы в дальнейшем наше государство сумело эффективно и беспрепятственно внедрить данную технологию. Именно этому будет посвящена статья. Были рассмотрены и проанализированы технологии на базе ИИ, опыт их применения в странах дальнего зарубежья и Российской Федерации, а также проблемы, с которыми сталкиваются ВУЗы при внедрении данных новшеств.
The relevance of this research work lies in the fact that recently the practical application of artificial intelligence in various spheres of people’s lives (industry, medicine, finance, trade, marketing, programming, entertainment and even in the selection of music) has been gaining popularity. Therefore, it is necessary to consider all available opportunities and prospects for the use of artificial intelligence in higher education of the Republic of Kazakhstan, so that in the future our state will be able to effectively and smoothly implement this technology. This is what the article will be devoted to. AI-based technologies, the experience of their application in non-CIS countries and the Russian Federation, as well as the problems that universities face when introducing these innovations were reviewed and analyzed.
Trends in the development of entrepreneurial activity of tourism organizations in RK
Authors: Кусаинова А.Б. , Сагындыкова Р.Е. 
Published: June 2024

Статья рассматривает актуальные тенденции развития предпринимательской деятельности в сфере туризма в Республике Казахстан. Автор анализирует основные изменения и вызовы, с которыми сталкиваются предприниматели в данной отрасли, такие как конкуренция, изменение потребностей потребителей и технологические инновации. Они также предлагают рекомендации по развитию бизнеса в туристской сфере, учитывая современные тренды и потребности рынка. В целом, статья даёт обзор текущего состояния и перспектив развития предпринимательства в туризме в Казахстане.
The article examines the current trends in the development of entrepreneurial activity in the field of tourism in the Republic of Kazakhstan. The author analyzes the main changes and challenges faced by entrepreneurs in this industry, such as competition, changing consumer needs and technological innovations. They also offer recommendations on business development in the tourism sector, taking into account current trends and market needs. In general, the article provides an overview of the current state and prospects for the development of entrepreneurship in tourism in Kazakhstan.
Long noncoding RNA RP11-704M14.1 Acts as a Sponge of miR-6756-5p to promote neuronal proliferation by Regulating ALOX15 Expression
Authors: Cao Ke , Gong Ru , Wang Jiancun , Yu Cong , Zheng Ping 
Published: June 2024

IntroductionLong noncoding RNAs (lncRNAs) mediate critical effects in central nervous system diseases; however, the exact role of lncRNAs in human traumatic brain injury (TBI) remains elusive. Considering the principles of primary prediction, targeted prevention, and personalized treatment medicine (PPPM), identifying specific novel biomarker associated with TBI and exploring the underlying mechanisms comprehensively are crucial steps towards achieving primary prediction, targeted prevention, and personalized treatment of TBI.Material and methodsIn this study, we integrated single-cell RNA sequencing (sc-RNA-seq) data and microarray chipset data for TBI to identify a competing endogenous RNA axis.ResultsWe detected 11 clusters based on the sc-RNA-seq data and identified Ifit1 as a marker gene co-expressed with ENST00000505646.1 (RP11-704M14.1). Additionally, the expression of IFIT1 and RP11-704M14.1 was found to decrease with the severity of TBI. RP11-704M14.1 promoted neuronal proliferation, and its knockdown prevented this effect. Furthermore, we found that RP11-704M14.1 functions as an miR-6756-5p sponge and increases the expression of its target gene ALOX15.ConclusionsOur results show that RP11-704M14.1 promotes neuronal proliferation by sponging miR-6756-5p and regulating ALOX15 expression in brain insults; accordingly, targeting this lncRNA presents a promising avenue for advancing the transition from reactive medicine to PPPM in managing traumatic brain injury, potentially leading to significant clinical benefits.
Voyage d’une théorie de la ponctuation : l’influence de Dolet sur Hart à travers Meigret
Authors: Calvo-Segurado Ana 
Published: June 2024

John Hart est le premier grammairien qui a écrit sur la ponctuation anglaise en langue vernaculaire en deux œuvres : The Opening of the Unreasonable Writing of our Inglish Toung (1551) et An Orthographie (1569). Réformateur de l’orthographe anglaise et phonéticien, il est admis qu’il en a pris inspiration de Louis Meigret. Néanmoins, l’analyse de sa théorie sur la ponctuation souligne l’influence d’un autre humaniste français : Étienne Dolet. Cet article traitera de démontrer que les idées de ce dernier ont surpassé les frontières géographiques et ont exercé une influence sur la première théorie sur la ponctuation en anglais.
Il était une forêt de Luc Jacquet, ou l’art du conte documentaire
Authors: Ramouche Marie-Pierre 
Published: June 2024

Après la consécration internationale de La marche de l’empereur, Luc Jacquet s’associe au célèbre botaniste et activiste Francis Hallé pour réaliser en 2013 le documentaire Il était une forêt, avec lequel il nous plonge dans l’univers fantastique des forêts tropicales primaires. En nous appuyant sur les travaux d’Estelle Zhong et de Bénédicte Meillon, nous nous proposons de démontrer que le documentaire Il était une forêt fait partie de ces œuvres « éco-sensibles » (Zhong, 2023) qui réenchantent (Meillon, 2018) l’imaginaire occidental dans ses rapports au non-humain.
Pour ce faire nous commencerons par replacer ce documentaire dans le contexte de l’émergence de l’éco-documentaire français qui a amené à se faire rencontrer cinéastes et scientifiques dans le but de sensibiliser les spectateurs à la cause écologique. Nous nous intéresserons ensuite aux dispositifs narratifs et esthétiques empruntés aux genres du merveilleux et de la fantasy qui font de cette œuvre un authentique « conte-documentaire » pour le plus grand plaisir des petits comme des grands.
Outcome of meniscal repairs in paediatric population: A tertiary centre experience
Authors: Gabr Ayman , Williams Samson , Dodd Sophie , Barton-Hanson Nick 
Published: June 2024

BACKGROUND
Meniscal sparing surgery is a widely utilised treatment option for unstable meniscal tears with the aim of minimising the risk of progression towards osteoarthritis. However, there is limited data in the literature on meniscal repair outcomes in skeletally immature patients.
AIM
To evaluate the re-operation rate and functional outcomes of meniscal repairs in children and adolescents.
METHODS
We performed a retrospective review of all patients who underwent arthroscopic meniscal repair surgery between January 2007 and January 2018. All patients were under the age of 18 at the time of surgery. Procedures were all performed by a single surgeon. Information was gathered from our hospital Electronic Patient Records system. The primary outcome measure was re-operation rate (need for further surgery on the same meniscus). Secondary outcome measures were surgical complications and patient reported outcome measures that were International Knee Documentation Committee (IKDC), Tegner and Lysholm scores.
RESULTS
We identified 59 patients who underwent 66 All-inside meniscal repairs (32 medial meniscus and 34 Lateral meniscus). Meniscal repairs were performed utilizing FasT-Fix (Smith and Nephew) implants. There were 37 males and 22 females with an average age of 14 years (range 6-16). The average follow-up time was 53 months (range 26-140). Six patients had concomitant anterior cruciate ligament reconstruction surgery along with the meniscal repair. There were no intra-operative complications. The re-operation rate for meniscal repairs was 16.6% (11 cases) with 2 patients requiring further meniscal repairs and 9 patients underwent partial meniscectomies. The mean postoperative IKDC score was 88 (44-100), Tegner score was 7(2-10) and Lysholm score was 94 (57-100).
CONCLUSION
Our results showed that arthroscopic repair of meniscal tears in the paediatric population is an effective treatment option that has a low failure rate and good postoperative clinical with the advantage of preserving meniscal tissues.
Three predictive scores compared in a retrospective multicenter study of nonunion tibial shaft fracture
Authors: Quarta Davide , Grassi Marco , Lattanzi Giuliano , Gigante Antonio Pompilio , D'Anca Alessio , Potena Domenico 
Published: June 2024

BACKGROUND
Delayed union, malunion, and nonunion are serious complications in the healing of fractures. Predicting the risk of nonunion before or after surgery is challenging.
AIM
To compare the most prevalent predictive scores of nonunion used in clinical practice to determine the most accurate score for predicting nonunion.
METHODS
We collected data from patients with tibial shaft fractures undergoing surgery from January 2016 to December 2020 in three different trauma hospitals. In this retrospective multicenter study, we considered only fractures treated with intramedullary nailing. We calculated the tibia FRACTure prediction healING days (FRACTING) score, Nonunion Risk Determination score, and Leeds-Genoa Nonunion Index (LEG-NUI) score at the time of definitive fixation.
RESULTS
Of the 130 patients enrolled, 89 (68.4%) healed within 9 months and were classified as union. The remaining patients (n = 41, 31.5%) healed after more than 9 months or underwent other surgical procedures and were classified as nonunion. After calculation of the three scores, LEG-NUI and FRACTING were the most accurate at predicting healing.
CONCLUSION
LEG-NUI and FRACTING showed the best performances by accurately predicting union and nonunion.
Pengaruh Strategi Koping Terhadap Tingkat Kecemasan Pada lanjut Usia (Lansia) Hipertensi di Puskesmas Tamalate Kota Makassar
Authors: Marliana Marliana , Asrina Andi , Arman Arman 
Published: June 2024

Pada masa lansia, fungsi tubuh mengalami penurunan. Salah satu penyakit yang diderita oleh lanisa adalah hipertensi. Hipertensi dapat menyebabkan masalah psikis pada lansia karena semakin tinggi hipertensi, lansia menjadi takut dan cemas terhadap kondisinya. sehingga diperlukan strategi koping. Penelitian ini bertujuan untuk mengetahui pengaruh problem focused coping dan emotion focused coping terhadap tingkat kecemasan pada lanjut usia (lansia) hipertensi di Puskesmas Tamalate Kota Makassar. Jenis penelitian ini adalah kuantitatif dengan desain Cross Sectional Study.Teknik pengambilan sampel dalam penelitian ini adalah purposive sampling yaitu sebanyak 154 sampel. Analisis data menggunakan uji statistic t-test dengan tingkat kemaknaan 95% (?: 0,05). Hasil penelitian menunjukkan Problem Focused Coping terhadap tingkat kecemasan p value P Value 0,009 dan nilai B -0.345. Emotion Focused Coping terhadap tingkat kecemasan pada nilai p value 0,000 dan B 0.275. Kesimpulan, terdapat pengaruh antara problem focused coping terhadap tingkat kecemasan pada lanjut usia (lansia) hipertensi dan arah pengaruh negative. Terdapat pengaruh antara emotion focused coping pada tingkat kecemasan pada lanjut usia (lansia) hipertensi dan arah pengaruh positif.
Review of the Implementation of Minimum Services for Loading Vehicles on Ships on the Bolok – Rote Route, East Nusa Tenggara Province
Authors: Sulistyorini Erika Dwi , Pusriansyah Ferdinand , Triwahyuni Siti Nurlaili , Aziz Dadang Abdul , Hatina Damaida , Ramadhani Shabrina 
Published: June 2024

The Minimum Service Standards for Ferry Transport are the minimum requirements that must be met by ferry transport companies in providing services to service users. Minimum Service Standards (SPM) inspection process so that when the ship operates it does not cause problems. However, in its implementation the Minimum Service Standards have not been implemented at the Bolok Ferry Port, especially for the Minimum Service Standards for Loading on 4 ships, namely: (1) KMP. Lakaan; (2) KMP. Skipjack II; (3) KMP. Uma Kalada; and (4) KMP. Inerie II on the Bolok – Rote route. The aim of this research is to determine the level or percentage of compliance with the Minimum Service Standards for Loading vehicles on 4 ships on the Bolok – Rote Route. The method used is an observation method in the form of a survey of the distance between vehicles and the level of conformity to Minister of Transportation Regulation Number 62 of 2019 concerning Minimum Service Standards for Ferry Transport. Based on the results of the analysis, it can be seen that on 4 (four) ships in The Bolok – Rote route does not comply with Ministerial Regulation Number 62 of 2019 concerning Minimum Service Standards (SPM) for Ferry Transport, namely: (1) KMP. The conformity rate was 62%; (2) KMP. Cakalang II conformity level of 62%; (3) KMP. Uma Kalada's conformity rate was 65.5%; and (4) KMP. Inerie II conformity rate is 65.5%. Based on the analysis, ship operators can increase the Minimum Service Standards (SPM) for vehicle loading, especially in the following aspects: (1) Safety aspects require improvements to sprinklers and smoke detectors; (2) Security aspects that require providing CCTV on the card deck and regulating the distance between vehicles; and (3) Convenience/affordability aspects include changes to the cardeck height, improvements to lights and fastening to the vehicle when sailing.
The Indonesia's Strategies For Exclusive Economic Zone (EEZ) Sovereignty With 1982 UNCLOS Provisions: North Natuna Sea
Authors: Budi Pramono  
Published: June 2024

North Natuna Sea's abundance of natural resources provides a tremendous pull for diverse parties, who, for the sake of profit maximization, are willing to commit any crime. A further report found that the claims of South East Asean countries and China on Indonesia's Exclusive Economic Zone (EEZ) waters in North Natuna Sea are completely divorced from the attractiveness of the natural resources. Considering the strategies to resolve any differences and the disputes between South East Asean countries and China in a peaceful manner through dialogue, affirming commitment to the goals and principles of UNCLOS, 1982, this paper provides a systematic review of the strategies as a the treaty of amity and cooperation in the South East Asian model for Indonesia’s stability which promotes agency and reflective practice. Comparing the current practice of the current waters’ cases in North Natuna Sea to the international stabilities reported in the literature, this review suggests that North Natuna Sea needs adopt two strategies that are concurrently executed and mutually supportive. The first is a diplomatic strategy consisting of two simultaneous steps, the first of which involves efforts to expedite the implementation of negotiations and the conclusion of a territorial boundary agreement between Indonesia and the Philippines, India, Malaysia, Palau, Singapore, Thailand, Timor-Leste, and Vietnam. sea. The second strategy is a defense diplomacy approach to China, by leveraging Indonesia-China bilateral defense cooperation and multilateral defense cooperation venues such as ARF and ADMM Plus where China is a discussion partner.
Key words: Indonesia, Exclusive Economic Zone (EEZ), Sovereignty, 1982 UNCLOS Provisions, North Natuna Sea
TINGKAT PENGETAHUAN MAHASISWA KEPERAWATAN TENTANG PHLEBITIS
Authors: Ahmad Yasin Hafidhuddin  , Aliana Dewi  , Puji Astuti Wiratmo  
Published: June 2024

Phlebitis merupakan komplikasi yang sering terjadi pada pemasangan peripheral intravena catheter yang ditandai dengan bengkak, kemerahan dan nyeri. Phlebitis dapat mengakibatkan terganggunya aliran infus dan menyebabkan infeksi pada peredaran darah. Mahasiswa perawat sebagai bagian dari tenaga kesehatan di lahan praktek perlu memiliki pengetahuan yang adekuat terhadap phlebitis agar kejadian phlebitis dapat dihindari. Penelitian ini bertujuan untuk mengetahui gambaran tingkat pengetahuan mahasiswa keperawatan tentang phlebitis. Penelitian ini menggunakan desain deskriptif kuantitatif dengan metode cross sectional. Penelitian ini dilakukan pada 44 mahasiswa menggunakan total sampling. Instrument untuk mengukur pengetahuan telah dilakukan uji validitas dan reliabilitas dengan Cronbach Alpha 0.871.Hasil penelitian menunjukkan bahwa tingkat pengetahuan mahasiswa keperawatan Universitas Binawan berada dalam kategori cukup dengan (45,5%), kategori kurang (43,2%) dan kategori baik (11,4%). Pengetahuan merupakan tingkatan kognitif yang awal yang perlu dicapai oleh mahasiswa keperawatan dalam menerapkan intervensi keperawatan khususnya pemasangan infus. Mahasiswa perlu meningkatkan pengetahuan dan keterampilan klinis dalam pemasangan infus sebagai upaya pencegahan dan penurunan angka kejadian komplikasi phlebitis.
STUDI KASUS: PERSPEKTIF GENERASI MUDA TERHADAP TEMPE MELALUI SOSIAL MEDIA
Authors: Maskar Dadi H , Anwar Khoirul , Prasetyo Irene Nuariza , Kusumawati Intan , Ridha Muhammad 
Published: June 2024

Tempe merupakan salah satu makanan budaya Indonesia yang sudah menjadi budaya sejak lama. Tempe memiliki banyak manfaat baik dari segi gizi, kesehatan, ekonomi, dan budaya. Penelitian ini menggunakan desain cross-sectional dengan metode survei dan pengisian kuesioner secara online dan mandiri. Penelitian ini dilakukan dari bulan Agustus sampai September 2022 yang dilakukan secara online. Survei dilakukan secara online dengan total responden 189 orang usia maksimal 30 tahun. Data diolah dengan menggunakan program komputer Microsoft Excel 2019. Analisis data yang digunakan adalah deskriptif dan inferensia. Analisis deskriptif dinyatakan dalam bentuk persentase dan rata-rata. Hasil penelitian diperoleh responden paling banyak pada penelitian ini yaitu usia 20-35 tahun (58,20%), perspektif responden mengenai tempe secara umum diantaranya tempe merupakan makanan budaya khas Indonesia (96,83%), bergizi tinggi (98,94%), superfood (84,66%), harga yang murah dan terjangkau (100%), dapat memberikan dampak ekonomi kepada masyarakat (91,01%). Sebanyak 94,18% responden pernah menggunakan tempe dalam perayaan, sebanyak 96,30% responden mengaku bangga dengan tempe dan 98,41% responden berpendapat bahwa pelestarian budaya tempe perlu untuk dilakukan. Berdasarkan hasil yang diperoleh disimpulkan bahwa generasi muda memiliki perspektif bahwa tempe merupakan salah satu makanan budaya Indonesia yang memiliki banyak manfaat, dan bangga terhadap tempe.
Pengembangan Formulasi Dan Evaluasi Mutu Sediaan Hair Tonic Ekstrak Bawang Merah (Allium Cepa L.)
Authors: Sari Kartika , Bachri Nurjannah , Mukhsin Akhmad , Laurensia Vivi , Indrawati Teti 
Published: June 2024

Bawang merah (Allium cepa L.) sebagai bumbu dapur dan obat tradisional; penyembuhan luka dan penyubur rambut. Sediaan penyubur rambut digunakan untuk menstimulasi pertumbuhan rambut. Penelitian ini bertujuan memperoleh ekstrak bawang merah bermutu baik, sediaan penyubur rambut ekstrak bawang merah 2%, 4% dan 6% memenuhi karakteristik sediaan hair tonic yang baik. Ekatraksi bawang merah dengan metode maserasi. Pembuatan hair tonic dengan metode pencampuran. Rendemen ekstrak bawang merah sebesar 30%, berbau khas aromatik, berwarna coklat, bebentuk kental, kadar sari larut air 57,22 ± 0,091, kadar sari larut etanol 40,7 ± 0,966, kadar abu 0,684 ± 0,199, kadar air 0,616 ± 0,210, susut pengeringan 0,79 ± 0,179, sisa etanol 0,06 ± 0,005, kandungan kimia; alkaloid, flavonoid, tannin, saponin, fenol. Sediaan hair tonic memenuhi karakteristik sediaan yang baik, berbetuk cair, F0 dan F1 tidak berwarna dan tidak berbau sementara untuk F2, F3 dan F4 berbau khas aromatik, berwarna coklat, viskositas 1,47-1,90 dan pH 5,87-6,10.