bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a short form of the valued life activities disability questionnaire for rheumatoid arthritis
Authors: Katz Patricia P. , Radvanski Diane C. , Allen Diane , Buyske Steven , Schiff Samuel , Nadkarni Anagha , Rosenblatt Lisa , Maclean Ross , Hassett Afton L. 
Published: September 2011

AbstractObjectiveTo develop and validate a shortened version of the Valued Life Activities disability and accommodations scale (VLA) for individuals with rheumatoid arthritis (RA).MethodsTo shorten the existing VLA measure, item response theory analyses were conducted using data from 449 patients with RA. Next, the resulting 14‐item shortened version of the VLA scale (S‐VLA) was evaluated by structured interviews among 20 RA patients. Lastly, the S‐VLA was administered to 150 RA patients along with other measures, including the Health Assessment Questionnaire (HAQ) and Short Form 36 (SF‐36). A random sample of 50 patients completed the S‐VLA 2 weeks later to assess reliability. Item statistics were calculated to evaluate correlations between individual items and the S‐VLA total score. Correlations between the S‐VLA and other measures were used to evaluate validity.ResultsTest–retest reliability was 0.91, while Cronbach's alpha for the S‐VLA was 0.95. None of the 14 items was associated with improved alpha coefficients when omitted. All of the items were strongly correlated with the S‐VLA total score. S‐VLA scores were highly positively correlated with the HAQ (r = 0.81, P ≤ 0.001), patient‐reported disease activity (r = 0.71, P ≤ 0.001), satisfaction with abilities (r = 0.82, P ≤ 0.001), and number of days with activity limitations (r = 0.65, P ≤ 0.001). In addition, as hypothesized, the S‐VLA was inversely correlated with the SF‐36 physical component summary score (r = −0.78, P ≤ 0.001) and the physical functioning (r = −0.80, P ≤ 0.001), role physical (r = −0.67, P ≤ 0.001), and social functioning (r = −0.72, P ≤ 0.001) subscales.ConclusionThe S‐VLA is a short, valid, and reliable instrument that may prove useful for monitoring disability among individuals with RA.
Recovery expectations of hip resurfacing compared to total hip arthroplasty: A matched pairs study
Authors: Ghomrawi Hassan M. K. , Dolan Mark M. , Rutledge John , Alexiades Michael M. 
Published: September 2011

AbstractObjectiveExpectations of higher activity levels associated with hip resurfacing arthroplasty (HRA) may be driving better outcomes in this group compared to total hip arthroplasty (THA). Previous studies evaluated patient expectations before consulting with the surgeon, although these expectations were likely unrealistic and would change after the consultation. We compared HRA and THA patient expectations after consultation with the surgeon.MethodsIn a prospective registry setting, patients awaiting HRA were matched to THA patients by age, sex, and a preoperative Lower Extremity Activity Scale score (range 1–18, with 18 indicating levels of highest activity). Patients completed preoperatively a validated 18‐item expectations survey. Mean overall expectation scores were first compared. Exploratory factor analysis (EFA) was then performed to determine if the grouping of individual expectations items represented meaningfully different underlying factors in the 2 groups.ResultsWe matched 123 pairs. The mean ± SD expectation scores were similar (85.2 ± 15.5 for HRA and 87.3 ± 13.9 for THA; P = 0.249). The EFA showed that HRA and THA patients shared the common expectations of pain relief and improvement in daily activities (9 items) and eliminating pain medications, the need for a cane, and improving sexual activity (3 items). THA patients perceived the remaining 6 items as an overall third expectation of participation in higher‐level activities. However, HRA patients perceived a fourth expectation of normal range of motion (2 items) independent of the other higher‐level activities (4 items).ConclusionEven after consulting with a surgeon, patients' expectations differed between HRA and THA patients regarding higher‐level activities. More counseling for patients seeking hip arthroplasty is therefore needed.
Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis
Authors: Beattie Karen A. , MacIntyre Norma J. , Ramadan Khaled , Inglis Dean , Maly Monica R. 
Published: September 2011

AbstractObjectiveTo quantify rates of change in quadriceps muscle (QM) and intermuscular fat (IMF) volumes over 2 years in women in the Osteoarthritis Initiative (OAI) study and examine group differences between those with radiographic osteoarthritis (ROA) and those without ROA.MethodsThe OAI database was queried for women ≥50 years of age in the incident and progression cohorts with and without ROA at baseline. Midthigh magnetic resonance imaging scans (15 contiguous slices, 5 mm slice thickness) of eligible women were randomly selected and anonymized. Image pairs were registered. QM and IMF were segmented in the 12 most proximal matching slices with the segmenter blinded to image time point. Age‐adjusted differences in QM and IMF volume changes between groups were tested using analysis of covariance.ResultsForty‐one women without ROA (mean ± SD age 60.7 ± 7.6 years) and 45 women with ROA (mean ± SD age 64.5 ± 6.7 years) were included. Mean ± SD QM and IMF volume changes in the non‐ROA group were −4.1 ± 11.1 cm3 and 3.4 ± 7.1 cm3, respectively, and −5.4 ± 13.5 cm3 and 3.1 ± 7.4 cm3 in the ROA group, respectively. Age‐adjusted between‐group differences in QM and IMF changes were not significant (P > 0.05).ConclusionTwo‐year changes in QM and IMF volumes appear consistent with aging and do not seem to be related to OA status. Direct comparison with a control cohort without OA risk factors could confirm this. Since group assignment was based on baseline data, there may have been women in the non‐ROA group who developed ROA over followup, resulting in some overlap between groups.
Generation of Amphiphilic Janus Bubbles and Their Behavior at an Air–Water Interface
Authors: Brugarolas Teresa , Park Bum Jun , Lee Myung Han , Lee Daeyeon 
Published: September 2011

AbstractThis paper presents the generation of amphiphilic Janus bubbles and their behavior at an air–water interface. Janus bubbles are generated by selectively depositing gold onto one side of dried nanoparticle‐shelled bubbles. To generate nanoparticle‐shelled bubbles that can withstand drying without significant changes in their structure, it is critical to control the ratio of bubble radius to shell thickness using a microfluidic technique. It is observed that the behavior of Janus bubbles at an air–water interface is very different from that of unmodified nanoparticle‐shelled bubbles. Interfacial assembly of amphiphilic Janus bubbles shows that they interact with one another via long‐ranged attractions. The origin of this long‐ranged attraction is quadrupolar capillary interactions due to the undulation of the three‐phase contact line around the Janus boundary. The interparticle forces between interface‐trapped Janus bubbles are determined using a particle tracking method. The shape of the deformed air–water interface around Janus bubbles is directly observed as well as the orientation of Janus bubbles using a gel‐trapping technique. These observations verify that the air–water interface is pinned around the boundary between the two hemispheres and that the chemical heterogeneity of this boundary leads to irregular contact line around Janus bubbles.
A Mesoporous, Silica‐Immobilized‐Nanoparticle Colorimetric Chemosensor for the Detection of Nerve Agents
Authors: Kim Hyun Jung , Lee Ji Ha , Lee Hyejin , Lee Jae Hong , Lee Joung Hae , Jung Jong Hwa , Kim Jong Seung 
Published: September 2011

AbstractA new and an easy‐to‐make colorimetric azo‐pyridine, 1, and its recyclable mesoporous silica‐immobilized nanoparticles for nerve‐agent detection are synthesized. The binding site, comprising an azo‐pyridine moiety, is capable of selectively sensing diethylchlorophosphate (DCP), one of the nerve‐agent mimics of chemical‐warfare agents, over a series of other phosphate compounds. Compound 1 shows ratiometric changes in absorption spectroscopy to the extent of a 60 nm red‐shift upon the addition of DCP, mainly due to a change in the intramolecular charge transfer (ICT) in 1. The color change of receptor 1 from yellow to red in the concentration region ≈1.0 × 10−6 M is sufficient for the selective detection of the DCP nerve‐agent mimic by the naked eye. With regards to solid‐phase application, mesoporous silica nanoparticles using 1 (MSIAP) are also prepared using a sol‐gel grafting reaction. The color of the MSIAP also changes from red to yellow when dipped into an aqueous DCP solution, and turns back to red when treated with NaOH solution, with nontoxic diethylphosphoric acid being given off. The absorption changes of MSIAP in the presence of DCP are consistent within the 3–9 pH range.
The Impact of Generalized Trust and Trust in the Food System on Choices of a Functional GM Food
Authors: Ding Yulian , Veeman Michele M. , Adamowicz Wiktor L. 
Published: September 2011

AbstractWe investigate the impact of trust on stated purchases for a food with health‐related attributes (omega‐3 content) that may be associated with fortification or genetically modified (GM) ingredients based on data from a Canada‐wide survey. Assessing the predictive power of various trust measures on consumers' food choices using latent class models indicates that respondents who are generally trusting and also trust the food system are less averse to GM food. The finding that generalized trust (measured by trust in strangers and past trusting behavior) also affects consumers' choices of GM food, suggests that some concerns about GM‐derived food are related to an individual's worldview and may be beyond the control of the food system.
The length‐times‐width proxy for leaf area of eelgrass:criteria for evaluating the representativeness of leaf‐width measurements
Authors: Echavarria‐Heras Hector , Solana‐Arellano Elena , Leal‐Ramirez Cecilia , Franco‐Vizcaíno Ernesto 
Published: September 2011

ABSTRACT

Conservation and remediation projects for Zostera marina populations require easy and economical methods for non‐destructive approximations of leaf area. Allometric models provide a reliable approach for estimating biomass in terms of leaf area, and the length‐times‐width proxy for leaf area is widely used.
Although leaf length of Z. marina can be unambiguously determined as the span from the ligula to the tip, different methods have been reported for obtaining representative measurements of leaf width.

Using allometric models and eelgrass leaf‐growth properties we derived criteria based on regression equations, for the assessment of the representativeness of leaf width as a determinant of leaf area. In comparison with other estimations reported in the literature, width measurements taken at the midpoint of the leaf produced the most consistent proxy values for leaf area of eelgrass.
Copyright © 2011 John Wiley & Sons, Ltd.
Bis(5,7‐dimethyl‐8‐hydroxyquinolinato)platinum(II) Complex for Efficient Organic Heterojunction Solar Cells
Authors: Low Kam‐Hung , Xu Zong‐Xiang , Xiang Hai‐Feng , Chui Stephen Sin‐Yin , Roy V. A. L. , Che Chi‐Ming 
Published: September 2011

AbstractOrganic photovoltaic (OPV) cells using metal(II) (Pt, Pd, Cu, and Ni) chelates of 8‐hydroxyquinoline (Hq) or 5,7‐dimethyl‐8‐hydroxy‐quinoline (HMe2q) as an electron donor were fabricated by vacuum deposition. The bis(5,7‐dimethyl‐8‐hydroxyquinolinato)platinum(II) [Pt(Me2q)2]‐based OPVs showed the best performance with an open voltage (VOC) of 0.42 V, a short circuit current density (JSC) of 14.8 mA cm−2, and a maximum power conversion efficiency (ηP) of 2.4 %. The X‐ray single‐crystal structures together with the grazing incidence X‐ray diffraction (GIXRD) data of thin film samples reveal that the peripheral methyl substituent(s) and platinum(II) ion are essential for the high degree of film crystallinity resulting in improved performance of the as‐fabricated field‐effect transistors (FETs) and OPV cells.
Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders
Authors: South Mikle , Larson Michael J. , White Sarah E. , Dana Julianne , Crowley Michael J. 
Published: September 2011

AbstractEvidence from behavioral and neuroimaging studies suggest that atypical amygdala function plays a critical role in the development of autism spectrum disorders (ASD). The handful of psychophysiological studies examining amygdala function in ASD using classical fear conditioning paradigms have yielded discordant results. We recorded skin conductance response (SCR) during a simple discrimination conditioning task in 30 children and adolescents (ages 8–18) diagnosed with high‐functioning ASD and 30 age‐ and IQ‐matched, typically developing controls. SCR response in the ASD group was uniquely and positively associated with social anxiety; and negatively correlated with autism symptom severity, in particular with social functioning. Fear conditioning studies have tremendous potential to aid understanding regarding the amygdale's role in the varied symptom profile of ASD. Our data demonstrate that such studies require careful attention to task‐specific factors, including task complexity; and also to contributions of dimensional, within‐group factors that contribute to ASD heterogeneity. Autism Res 2011,4:412–421. © 2011 International Society for Autism Research, Wiley Periodicals, Inc.
Sociodemographic risk factors associated with autism spectrum disorders and intellectual disability
Authors: Pinborough‐Zimmerman Judith , Bilder Deborah , Bakian Amanda , Satterfield Robert , Carbone Paul S. , Nangle Barry E. , Randall Harper , McMahon William M. 
Published: September 2011

AbstractThis study examined the hypotheses that (1) sociodemographic risk factors in young children with autism spectrum disorders (ASD) and/or intellectual disability (ID) significantly vary by disability type, and (2) measures of income (mean adjusted gross income, mean federal taxes paid, and mean tax exemptions) significantly increase between 1994 and 2002, and are lower in families with a child with ASD and/or ID compared with the general population. A multiple source surveillance system utilizing a retrospective record review was used to identify ASD and ID cases from a population of 26,108 eight‐year‐old children born in 1994 and living in Utah in 2002. ASD without ID (ASD‐only, n = 99) cases were significantly more likely to be male (P<0.01) and have mothers of White non‐Hispanic ethnicity (P = 0.02). ASD with ID (ASD/ID, n = 33) cases were significantly more likely to be male (P<0.01) and have mothers older than 34 years (P = 0.03). ID without ASD (ID‐only, n = 113) cases were significantly more likely to have fathers older than 34 years (P<0.01) and were significantly less likely to have mothers with >13 years education (P<0.01). Measures of income for cases at birth and at 8 years of age were not significantly lower than the general population and mean adjusted income of cases significantly increased from birth to 8 years of age. Investigations focused on defining early sociodemographic risk factors by different endophenotypes of ASD may assist in identifying risk factors for this complex group of neurodevelopmental disorders. Aggregate tax information may be a unique resource to utilize for population‐based analysis. Autism Res 2011,4:438–448. © 2011 International Society for Autism Research, Wiley Periodicals, Inc.
Evidence for broader autism phenotype characteristics in parents from multiple‐incidence autism families
Authors: Bernier Raphael , Gerdts Jennifer , Munson Jeff , Dawson Geraldine , Estes Annette 
Published: September 2011

AbstractThe broader autism phenotype (BAP) was assessed in parents who have two or more children with autism spectrum disorder (ASD) (multiplex (MPX) autism), parents who have no more than one child with ASD (simplex autism), parents who have a child with developmental delay without ASD, and parents who have typically developing children. Clinicians, naive to parent group membership status, rated BAP characteristics from videotaped administration of the Broader Autism Phenotype Symptom Scale (BPASS). Differences among groups in BPASS scores in the four assessed domains (social motivation, conversational skills, expressiveness, and restricted interests) were examined using multivariate ANOVA and post hoc comparisons. Further, ratings of videotapes by observers naïve to family status were compared with live, non‐naive ratings by observers who were aware of family status (non‐naïve). Findings demonstrate that the BPASS is an instrument resistant to rater bias. Parents from MPX autism families showed significantly more autism phenotype characteristics than the parents in the other groups. Moreover, the parents from simplex autism families did not differ from the parents of children with developmental delay or typical development. Finally, no differences between live, non‐naive ratings and videotaped, naive ratings were observed. These findings suggest that characteristics of the BAP, specifically in the social and communication domains, are present in MPX autism parents to a greater degree than simplex autism and control parents. Further, the results provide support for the notion that genetic transmission mechanisms may differ between families with more than one child with autism and families with only one child with autism. Autism Res 2012,5:13–20. © 2011 International Society for Autism Research, Wiley Periodicals, Inc.
Soy protein recovery in a solvent‐free process using continuous liquid–solid circulating fluidized bed ion exchanger
Authors: Prince Andrew , Bassi Amarjeet S. , Haas Christine , Zhu Jesse X. , Dawe Jennifer 
Published: September 2011

AbstractSoy protein concentrates and soy protein isolates act as ingredients in bakery, meat and dairy products, baby formulas, starting materials for spun textured vegetable products, and other nutritional supplements. In this study, the effectiveness of a liquid–solid circulating fluidized bed (LSCFB) ion exchanger is demonstrated for the recovery of soluble soy proteins from full fat and defatted soy flour. Under steady‐state operating conditions, about 50% of the proteins could be recovered from the feed streams entering the ion exchanger. The LSCFB was shown to be a promising system for the recovery of soy protein from both defatted and full fat soy flour solutions. As the ion exchange process captures dissolved proteins, the system may offer a less damaging form of processing compared with the acid precipitation process where soy protein aggregates form and functionality is affected. In addition, the LSCFB allows simultaneous adsorption and desorption of the proteins allowing for a continuous operation. No prefiltration of feed containing suspended particles is required as well, because fluidization is used in place of packed bed technology to improve on current ion exchange processes. © 2011 American Institute of Chemical Engineers Biotechnol. Prog., 2012
Left or Right? The Direction of Compression‐Generated Vortex‐Like Flow Selects the Macroscopic Chirality of Interfacial Molecular Assemblies
Authors: Chen Penglei , Ma Xiaoguang , Hu Kaiming , Rong Yunlong , Liu Minghua 
Published: September 2011

AbstractA new method is described through which the macroscopic chirality of interfacial molecular assemblies of an achiral porphyrin can be mechanically controlled using an original yet efficient Langmuir–Blodgett (LB) technique. By using the unilateral compression geometry, we find that the assemblies deposited from the mirror regions of the LB trough display mirror macroscopic chirality. It is indicated that vortex‐like flows could be generated during compression, and that it is the direction of this compression‐generated vortex‐like flow that determine the macroscopic chirality of the formed assemblies. Moreover, the standard sample‐fabrication method with bilateral compression geometry is reformed, and we find that the samples formulated around the left‐hand‐ and right‐hand‐side Langmuir barriers display opposite macroscopic chiralities. The results suggest that mechanically controlled supramolecular chirogenesis could be efficiently realized through such an LB technique. The investigation establishes a new forum for further investigation of the mechanically induced preferred supramolecular chirality in terms of interfacial organization, and provides the old LB technique with new opportunities for controlling the macroscopic chirality of a supramolecular system that is wholly composed of achiral units.
Silica‐supported Perchloric Acid Catalyzed One‐pot Synthesis of 1,4‐Dihydropyridines
Authors: Ramesh Dasari , Rajaram Singanaboina , Narasimhulu Manchala , Reddy Thummalpally Srikanth , Mahesh Kondempudi Chinni , Manasa Gajji , Venkateswarlu Yenamandra 
Published: September 2011

AbstractAn environmentally friendly and highly efficient procedure for the preparation of 1,4‐dihydropyridines by the reaction between α,β‐unsaturated aldehydes, aromatic amines and β‐keto esters in the presence of silica supported perchloric acid is described.
Highly Enantioselective Synthesis of α‐Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl‐substituted Thiourea Catalyst Derived from Amino Acid
Authors: Li Peng , Zhao Gang , Zhu Shizheng 
Published: September 2011

AbstractAn enantioselective Michael addition of ethyl 4,4,4‐trifluoro‐3‐oxobutanoate to α,β‐unsaturated ketone esters using a chiral alkyl‐substituted thiourea catalyst is reported. Excellent levels of stereo‐induction (up to 98% ee) under mild reaction conditions were obtained to afford the corresponding α‐trifluoromethyldihydropyrans.
ALD and MOCVD of Ga2O3 Thin Films Using the New Ga Precursor Dimethylgallium Isopropoxide, Me2GaOiPr
Authors: Lee Heeju , Kim Kunhee , Woo Jeong‐Jun , Jun Doo‐Jin , Park Youngsoo , Kim Yunsoo , Lee Hong Won , Cho Yong Jai , Cho Hyun Mo 
Published: September 2011

AbstractThin films of gallium oxide (Ga2O3) are prepared by using a new gallium precursor, dimethylgallium isopropoxide (DMGIP), employing both atomic layer deposition (ALD) and metal‐organic (MO)CVD. The gallium precursor DMGIP, a gallium analogue of dimethylaluminum isopropoxide (DMAIP) that has been successfully used for MOCVD and ALD of aluminum oxide, is likewise a non‐pyrophoric liquid at room temperature with a reasonably high vapor pressure. Using water as the oxygen source, DMGIP shows an ALD temperature window in the range 280–300 °C with a growth rate of ∼0.3 Å per cycle. On the other hand, using oxygen as the reactant gas in the MOCVD of Ga2O3, films are grown in the temperature range 450–625°C with the apparent activation energy of 225.5 kJ mol−1. This study shows that DMGIP can be utilized as a new source for the preparation of Ga2O3 thin films.