bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental investigation on oxygenation efficiency of an effective aeration system for ponds
Authors: Kelestemur Guluzar Tuna , Aytac Ayca , Tuna M. Cihat 
Published: June 2024

AbstractDissolved oxygen (DO) concentration in water is one of the most important water quality parameters in rivers, lakes, and reservoirs. The most effective way to increase DO concentration in water is aeration. Conduits with high aeration performance are predicted to significantly increase aeration efficiency. Based on this prediction, the physical parameters affecting the aeration efficiency (E20) of the conduit aeration system were experimentally investigated. The effect of different jet plunge angles, flow rates, hydrostatic levels, Froude numbers, and gate opening rates was investigated to optimize the system for the best ventilation efficiency. As a result, the aeration efficiency (E20) improves with increasing air intake performance at low gate openings, high Froude numbers, and hydrostatic levels. The increase in jet plunge angles and hydrostatic level directly increases the aeration efficiency. The study showed that conduit systems can be an important alternative for pond aeration due to initial investment and operating costs, low energy cost, and high aeration efficiency.
Phenotypic and molecular characterization of pleiotropic resistance to rusts and powdery mildew in spring wheat
Authors: Draz Ibrahim S. , Esmail Samar M. , Komeil Doaa A. 
Published: June 2024

AbstractAn attempt was undertaken to comprehend how phenotypic markers, leaf tip necrosis (LTN), and pseudo black chaff (PBC), are associated with pleiotropic resistance genes in wheat (Triticum spp.). Pleiotropic resistance to stripe rust (Puccinia striiformis f. sp. tritici), leaf rust (P. triticina), stem rust (P. graminis f. sp. tritici) and powdery mildew (Blumeria graminis f. sp. tritici) was evaluated in 57 Egyptian spring wheat cultivars at seedling stage in greenhouse and at adult plant stage in field during 2021/22 and 2022/23. At seedling stage, pleiotropic resistance rated moderately resistance (MR) was observed in five cultivars, Misr-3 (all three rusts), Misr-4 (stripe rust, leaf rust, powdery mildew), Giza-168 (leaf rust, stem rust, powdery mildew), Sakha-94 and Sids-13 (leaf rust, stem rust). At adult plant stage, Misr-4 outperformed all other evaluated cultivars, exhibiting a high level of pleiotropic adult plant resistance (PAPR) against all diseases investigated. High levels of PAPR were also noticed against the three rusts in nine cultivars, Misr-3, Sakha-93, Sakha-94, Sakha-95, Giza-156, Giza-168, Giza-171, Gemmeiza-10 and Sids-13, and moderate levels against powdery mildew in Misr-3, Sakha-95, Giza-156. Four PAPR genes were characterized in cultivars based on phenotypic and molecular markers. Phenotypic markers (LTN and PBC) were observed in 23 cultivars. Molecular marker csLV34 indicated the presence of Lr34/Yr18/Sr57/Pm38/Ltn1 in six cultivars, whilst marker Xwmc44 indicated that Lr46/Yr29/Sr58/Pm39/Ltn2 was present in five cultivars. Marker Xcfd71 indicated the presence of Lr67/Yr46/Sr55/Pm46/Ltn3 in 19 cultivars. Gene Sr2/Yr30/Lr27/Pbc was identified with marker csSr2 in three cultivars. A complete association between LTN and molecular markers was recorded, while a strong association (r = 0.73) was recorded between PBC and molecular markers. Findings demonstrated the reliability of phenotypic markers in predicting pleiotropic resistance in wheat, which would facilitate marker-assisted selection in breeding programs.
Low pH adaptation of tropical exotic acid tolerance yellow maize donor lines in sub-tropical breeding programs
Authors: Nginamau Dibanzilua , Kamutando Casper Nyaradzai , Magorokosho Cosmos , Saraiva João Constâncio , van Biljon Angeline , Labuschagne Maryke 
Published: June 2024

AbstractSoil acidity is one of the most important constraints to maize production in Angola, where both yellow and white maize is essential for food and feed requirements. In this study, four yellow acid soil tolerant donor lines from the International Maize and Wheat Improvement Centre (CIMMYT)—Colombia were crossed with ten yellow elite lines adapted to the mid-altitude climatic conditions developed by CIMMYT—Zimbabwe, in order to identify donor lines, which can be potential sources of acid tolerance genes in breeding programs in Angola and within the mid-altitude climatic zones. The two groups of parents were crossed using a line by tester mating design, yielding 36 crosses with sufficient seed, which were evaluated alongside six acid tolerant commercial hybrids, during the 2014–16 cropping seasons at nine sites, representing acid and non-acid soils in Angola and Zimbabwe. A significant (p < 0.05) line and line × tester effect for grain yield performance was observed across acid and non-acid conditions. Acid tolerance donor lines CY3 and CY1 showed the highest positive GCA effects for grain yield. In addition, crosses involving these two donor lines had the best yielding ability and stability under both acid and non-acid conditions. For instance, the crosses CH142464 (ZY2 × CY3) and, CH142447 (ZY2 × CY1) were the best combinations for grain yield performance under both acid and non-acid soil conditions, and were stable compared to the commercial check hybrids. Crosses involving the acid tolerant donor lines mostly flowered earlier than the commercial checks. Overall, the data showed the potential of tropically-adapted exotic yellow maize acid tolerance donor lines in improving productivity of sub-tropical maize under both low-pH and well-managed soil conditions.
Correlation of powers of Hüsler–Reiss vectors and Brown–Resnick fields, and application to insured wind losses
Authors: Koch Erwan 
Published: June 2024

AbstractHüsler–Reiss vectors and Brown–Resnick fields are popular models in multivariate and spatial extreme-value theory, respectively, and are widely used in applications. We provide analytical formulas for the correlation between powers of the components of the bivariate Hüsler–Reiss vector, extend these to the case of the Brown–Resnick field, and thoroughly study the properties of the resulting dependence measure. The use of correlation is justified by spatial risk theory, while power transforms are insightful when taking correlation as dependence measure, and are moreover very suited damage functions for weather events such as wind extremes or floods. This makes our theoretical results worthwhile for, e.g., actuarial applications. We finally perform a case study involving insured losses from extreme wind speeds in Germany, and obtain valuable conclusions for the insurance industry.
Rape Myths, Rape Law and Mendelsohn’s Victimology: Law’s ‘Bio-psycho-social’ Witness
Authors: Stringer Rebecca 
Published: June 2024

AbstractThis article provides a feminist reading of a neglected text: victimology founder Benjamin Mendelsohn’s essay about rape victims and the law, ‘Rape in Criminology and the Importance of the Female Judge’ (Mendelsohn Benjamin in La Giustizia Penale I-II-III-IV:28–50 1940). Following the heuristics of feminist socio-legal scholarship, my reading unsettles the established origin story of victimology and furthers feminist knowledge about the persistence of rape myths. I show victimology sprang from Mendelsohn’s work as a rape trial lawyer and was a vehicle for modernising rape myths, brought into being in response to rape survivor-corroborating advancements in forensic science. Mendelsohn’s ‘bio-psycho-social’ method of criminal defence sought a modern scientific foundation for rape myths, mobilising biological, psychoanalytic and sociological knowledge to contrive new grounds for invalidating complainant testimony as corrupt data.
Surface Erosion Equations for Degradation Analysis of Several Common Three-Dimensional Shapes of Plastic Materials
Authors: Dotson Kirk W. , Pisano Kyle , Renegar D. Abigail 
Published: June 2024

AbstractEquations were derived for the biodegradative erosion of the surfaces of arbitrarily-sized circular and square objects, i.e., the decrease in volume caused by the catalytic activity of enzymes secreted by microorganisms attached to the object surfaces. Surface erosion is the primary mode of biodegradation for polyhydroxyalkanoate (PHA) objects resting on the ocean floor. Although the derivations were motivated by a need to assess the time-varying biodegradation and ultimate disintegration of PHA tubes and straws in the benthic environment, generality was maintained during the mathematical development such that the resulting equations are also applicable to other circular and square objects, including cylindrical rings, discs, and solid rods, and square plates, cubes, and prisms. Moreover, the equations are applicable to abiotic degradation via physical erosion, not just to biotic degradation caused by microbes. Surface erosion is expressed in terms of the ratio of the instantaneous mass to the initial mass, which is generally nonlinear with respect to time. The value of this ratio and the relative dimensions of the object establish a surface erosion function and its evolution over the lifetime of the object. Hence, the rate of degradation is not constant in the theory, but rather is prescribed by the irregular mass loss and the original geometry of the 3D object.
Evaluation of the Accuracy of the Smart Work Injury Management (SWIM) System to Assist Case Managers in Predicting the Work Disability of Injured Workers
Authors: Yeung Yumiki Y. K. , Chen Peter Q. , Ng Peter H. F. , Cheng Andy S. K. 
Published: June 2024

Abstract
Purpose
Many countries have developed clinical decision-making support tools, such as the smart work injury management (SWIM) system in Hong Kong, to predict rehabilitation paths and address global issues related to work injury disability. This study aims to evaluate the accuracy of SWIM by comparing its predictions on real work injury cases to those made by human case managers, specifically with regard to the duration of sick leave and the percentage of permanent disability.

Methods
The study analyzed a total of 442 work injury cases covering the period from 2012 to 2020, dividing them into non-litigated and litigated cases. The Kruskal–Wallis post hoc test with Bonferroni adjustment was used to evaluate the differences between the actual data, the SWIM predictions, and the estimations made by three case managers. The intra-class correlation coefficient was used to assess the inter-rater reliability of the case managers.

Results
The study discovered that the predictions made by the SWIM model and a case manager possessing approximately 4 years of experience in case management exhibited moderate reliability in non-litigated cases. Nevertheless, there was no resemblance between SWIM’s predictions regarding the percentage of permanent disability and those made by case managers.

Conclusion
The findings indicate that SWIM is capable of replicating the sick leave estimations made by a case manager with an estimated 4 years of case management experience, albeit with limitations in generalizability owing to the small sample size of case managers involved in the study.

Implications
These findings represent a significant advancement in enhancing the accuracy of CDMS for work injury cases in Hong Kong, signaling progress in the field.
Urban landscape pattern mainly drives the early epidemic distribution of dengue fever in Hangzhou, China
Authors: Zhao Xinyu , Sun Yangyang , Xu Jialu , Hu Jinli , Wu Jueying , Hu Guang , Wen Yanping 
Published: June 2024

Abstract
Context
A new dengue fever (DF) epidemic in Hangzhou, China has placed a serious burden on the urban sustainable development. However, the key drivers of DF epidemic are still unclear, especially the effects of urban landscape patterns.

Objectives
In the present study, the spatial relationships between DF epidemic and urban landscape attributes in Hangzhou were investigated based on the framework and approach of landscape epidemiology.

Methods
The landscape indices of green space, waterbody, and built-up area were calculated based on land cover and land use (LULC) data. Population density, road density, GDP, and property price were used to represent socioeconomic conditions. The densities of social gathering places (SGPs) such as restaurants, malls, services, entertainment, traditional markets, and parks were recorded. A geographically weighted zero-inflated poisson regression (GWZIPR) model was applied to analyze the effects of LULC patterns, socioeconomic conditions, and SGPs on the risk of DF epidemics. An additional ZIPR-LASSO algorithm was used to explore the dominant drivers of spatial patterns of DF risk to construct the optimal model.

Results
DF cases were mainly clustered in central Hangzhou. Landscape patterns involving LULC and SGPs played a more important role in DF epidemic than the socioeconomic conditions. Among these factors, the total area of built-up area had the greatest effect to DF risk. Furthermore, property price, density of entertainment and services could better explain the spatial variation of DF risk in Hangzhou.

Conclusions
Overall, the contribution of landscape patterns to the DF epidemic was more important than socioeconomic conditions within the urban region, especially in the new epidemic region. These findings revealed the key role of landscape epidemiology in public health management and landscape governance to improve the urban sustainable development and human well-being.
Detecting the key role of the family in explaining corporate heritage use in family firms
Authors: D’Allura Giorgia Maria , Quarato Fabio , Dagnino Giovanni Battista , Merlo Elisabetta 
Published: June 2024

AbstractThis paper looks at the socioemotional wealth (SEW) priorities to reveal how family involvement in the firms affects their use of heritage as a marketing signal, thereby leading to a corporate heritage identity. Built considering the distinction between extended and restricted family’s SEW framework, we find a direct relationship between the presence of a family CEO and the use of heritage, that is moderated by the family involvement in the board and by the generational stage. Our empirical analysis employs a quantitative approach applied to a sample of medium- and large-sized firms examined over the period from 2000 to 2016.
Adaptation and content validation of measure yourself medical outcomes profile (MYMOP) for 7–11 year-old children
Authors: Ishaque S. , Roberts R. M. , Karnon J. , Thomas D. , Salter A. B. 
Published: June 2024

Abstract
Background
The Measure Yourself Medical Outcome Profile (MYMOP) is an individualised tool designed for adults but used with children without any evidence of validation in this population. Individualised instruments are patient-specific rather than disease-specific and therefore can be applied across various health conditions. This study sought to adapt, and content validate the MYMOP for application in 7–11 year old children.

Methods
There were two main phases of the four iterations: expert consultation (three rounds) and interviews with child-parent pairs at the Outpatient clinics of a Children’s Hospital. Thematic analysis was undertaken using an inductive, interpretative approach.

Results
Four paediatricians completed the first survey, five paediatricians participated in the focus group, and four paediatric health-related quality of life (HRQOL) research experts completed the second survey. Several changes were recommended to the MYMOP by the expert groups. Twenty-five children (17 general medicine, and 8 diabetes/endocrine clinic) aged 7–11 years completed the draft paediatric MYMOP (P-MYMOP) and were interviewed. Results demonstrated that the majority of participants were able to identify their own problems and activity limitations, and all participants understood the 7-point faces scale. Most parents and children perceived that the P-MYMOP would be useful to complete before clinic appointments.

Conclusions
The P-MYMOP is the first content-validated generic individualised HRQOL measure for children 7–11 years old. Given that validation is an iterative process, further research to assess its feasibility, reliability, and construct validity is required.
State-Level Antitrust Enforcement: Revisiting the Determinants
Authors: Feinberg Robert M. , Reynolds Kara M. 
Published: June 2024

AbstractState-level antitrust enforcement has historically been an important tool that promotes competition in the U.S. The total number of cases that were filed between 1990 and 2006 averaged 22 per year, and generally fluctuated in a fairly tight band. In an earlier article we found that political and macroeconomic variables tended to explain well these filing patterns. However, since then the number of state cases filed has dropped dramatically and averaged just 12 cases over the five years that preceded Covid. In this paper we consider again the political economy of antitrust enforcement at the state level: we find similar explanations to our 2010 article, with the size of the state economy, the macroeconomic conditions that face the state, and the political party in charge of enforcement continuing to drive antitrust filing activity.
Characterizing phenotypic data of Peromyscus leucopus compared to C57BL/6J Mus musculus and diversity outbred (DO) Mus musculus
Authors: Wimer Lauren A. , Davis-Castillo Asia , Galkina Sofiya , Ciotlos Serban , Patterson Cavan , Prado Leandro , Munoz Maria Castro , Martin Nicolas , Epstein Sharon , Schaum Nicholas , Melov Simon 
Published: June 2024

AbstractTranslational research is commonly performed in the C57B6/J mouse strain, chosen for its genetic homogeneity and phenotypic uniformity. Here, we evaluate the suitability of the white-footed deer mouse (Peromyscus leucopus) as a model organism for aging research, offering a comparative analysis against C57B6/J and diversity outbred (DO) Mus musculus strains. Our study includes comparisons of body composition, skeletal muscle function, and cardiovascular parameters, shedding light on potential applications and limitations of P. leucopus in aging studies. Notably, P. leucopus exhibits distinct body composition characteristics, emphasizing reduced muscle force exertion and a unique metabolism, particularly in fat mass. Cardiovascular assessments showed changes in arterial stiffness, challenging conventional assumptions and highlighting the need for a nuanced interpretation of aging-related phenotypes. Our study also highlights inherent challenges associated with maintaining and phenotyping P. leucopus cohorts. Behavioral considerations, including anxiety-induced responses during handling and phenotyping assessment, pose obstacles in acquiring meaningful data. Moreover, the unique anatomy of P. leucopus necessitates careful adaptation of protocols designed for Mus musculus. While showcasing potential benefits, further extensive analyses across broader age ranges and larger cohorts are necessary to establish the reliability of P. leucopus as a robust and translatable model for aging studies.
Levamisole Impairs Vascular Function by Blocking α-Adrenergic Receptors and Reducing NO Bioavailability in Rabbit Renal Artery
Authors: Guerra-Ojeda Sol , Marchio Patricia , Suarez Andrea , Aldasoro Martin , Valles Soraya L. , Genoves Patricia , Vila Jose M. , Mauricio Maria D. 
Published: June 2024

AbstractLevamisole is an anthelmintic drug restricted to veterinary use but is currently detected as the most widely used cocaine cutting agent in European countries. Levamisole-adulterated cocaine has been linked to acute kidney injury, marked by a decrease in glomerular filtration rate, which involves reduced renal blood flow, but data on the alteration of renovascular response produced by levamisole are scarce. Renal arteries were isolated from healthy rabbits and used for isometric tension recording in organ baths and protein analysis. We provide evidence that depending on its concentration, levamisole modulates renovascular tone by acting as a non-selective α-adrenergic receptor blocker and down-regulates α1-adrenoceptor expression. Furthermore, levamisole impairs the endothelium-dependent relaxation induced by acetylcholine without modifying endothelial nitric oxide synthase (eNOS) expression. However, exposure to superoxide dismutase (SOD) partially prevents the impairment of ACh-induced relaxation by levamisole. This response is consistent with a down-regulation of SOD1 and an up-regulation of NADPH oxidase 4 (Nox4), suggesting that endothelial NO loss is due to increased local oxidative stress. Our findings demonstrate that levamisole can interfere with renal blood flow and the coordinated response to a vasodilator stimulus, which could worsen the deleterious consequences of cocaine use.
Graphical Abstract
EFS electric field stimulation, NA noradrenaline, AR adrenergic receptor, IP3 inositol 1, 4, 5-trisphosphate, cAMP cyclic adenosine monophosphate, mAChR muscarinic acetylcholine receptor, eNOS endothelial nitric oxide synthase, sGC soluble guanylyl cyclase, SOD superoxide dismutase, NOX4 NAPH oxidase 4
SFXN3 is a Prognostic Marker and Promotes the Growth of Acute Myeloid Leukemia
Authors: Jin Fengbo , He Limei , Wang Jing , Zhang Yu , Yang Mingzhen 
Published: June 2024

AbstractAcute myeloid leukemia (AML) is a heterogeneous disease with rapid progression and frequent mutations. Sideroflexin3 (SFXN3) has been shown to be involved in various neurodegenerative diseases. However, the role of SFXN3 in AML remains unclear. The level and prognostic value of SFXN3 were assessed in pan-cancer, especially AML, based on the data obtained from the TCGA database. The effect and mechanism of SFXN3 in AML were measured by fluorescence-activated cell sorting (FACS), qRT-PCR, western blotting in vitro and in vivo. The correlation between SFXN3 and the infiltration of immune cells in AML was assessed via cibersort and ssGSEA analyses. SFXN3 is expressed at higher levels in AML, and high SFXN3 level is associated with decreased overall survival rate (OSR) in AML. Next, knockdown of SFXN3 results in enhanced cell apoptosis and dropped cell proliferation. Then, knockdown of SFXN3 caused a reduction in the expression of CyclinD1 (CCND1) and nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1). Finally, SFXN3 may related to the immunosuppressive state of AML. Increased SFXN3 expression is detected in AML, which indicates a poor prognosis and may link to immunosuppressive state of AML. In addition, SFXN3 can inhibit AML cells apoptosis and promote cell proliferation via enhancing CCND1 and NFKB1 levels.
Short- and medium-term impacts of small-scale vegetable support on food security: evidence from Syria
Authors: Baliki Ghassan , Al Daccache Melodie , Ghattas Hala , Brück Tilman 
Published: June 2024

AbstractSmall-scale agricultural and horticultural interventions play a critical role in improving nutrition and food security of vulnerable households in peaceful settings. However, scant rigorous evidence exists on the impacts and sustainability of such interventions in conflict settings. In this paper, we address this knowledge gap by analyzing the short- and medium-term impacts of a small-scale vegetable input support program involving asset transfers on food security and diets in war-time Syria. We use longitudinal panel household survey data from a quasi-experimental study collected at three rounds: before, one year, and two years after the horticultural intervention ended. We use propensity score matching and fixed-effect regression models to estimate the average treatment effects on the treated. We find that the vegetable support significantly improves food security by 21% and 19% in the short- and medium-term, respectively. More specifically, we find that the intervention significantly increased the consumption of nutrient-rich food groups such as vegetables, root tubers, fruits, eggs, pulses and nuts, milk, and oil and fats. Moreover, we find that the intervention reduces in the short-term the use of harmful coping strategies by 17%. However, this effect dissipates two years after the end of the intervention. The findings underscore the importance of small-scale vegetable support in addressing food insecurity in protracted conflict settings.