bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulary Drug Reviews - Colchicine
Authors: Cada Dennis J. , Levien Terri L. , Baker Danial E. 
Published: March 2010

Each month, subscribers to The Formulary Monograph Service receive five to six well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing inservices. A comprehensive target drug utilization evaluation (DUE) is also provided each month. With a subscription, the monographs are sent in print and are also available online. Monographs can be customized to meet the needs of a facility. Subscribers to The Formulary Monograph Service also receive access to a pharmacy bulletin board, The Formulary Information Exchange (The F.I.X.). All topics pertinent to clinical and hospital pharmacy are discussed on The F.I.X. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. For more information about The Formulary Monograph Service or The F.I.X., call The Formulary at 800-322-4349. The March 2010 class review is on calcium channel blockers for injection and the monograph topics are on tocilizumab, capsaicin 8% patch, olanzapine extended-release injectable, von Willebrand factor/coagulation factor VIII complex, and pirfenidone. The DUE is on tocilizumab.
Anger rumination, social support, and cardiac symptoms in patients undergoing angiography
Authors: León Trini Closa , Nouwen Arie , Sheffield David , Jaumdally Rumi , Lip Gregory Y. H. 
Published: March 2010

Objectives. Socially isolated individuals report more cardiac symptoms, suffer increased cardiovascular morbidity and mortality, and experience higher levels of stress and anxiety than those with more effective support resources. However, the complex interactions of psychosocial factors implicated in the disease process remain to be fully elucidated. We sought to explore these relationships, with the addition of a novel psychosocial variable, anger rumination, which could be associated with increased cardiovascular risk.Design. We examined the association of psychological stress, social support, and anger rumination, with surgical anxiety, self‐reported cardiac symptoms, and angiographically documented coronary artery disease, using a correlational ex post facto design.Methods. One hundred and one patients scheduled for elective coronary angiography completed questionnaires during the week prior to angiography. Disease severity was objectively assessed using the Gensini scoring system.Results. Self‐reported cardiac symptom severity was significantly correlated with higher perceived stress, less social support, and higher anger rumination, but none of the psychosocial variables predicted Gensini score. Social support partially mediated the relationship between anger rumination and surgical anxiety. Perceived stress mediated the relationship between anger rumination and cardiac symptoms.Conclusions. For patients awaiting angiography, stress, and lack of social support are important predictors of self‐reported cardiac symptoms, irrespective of actual disease severity. Intervention could focus on reducing perceived stress by encouraging reappraisal and a support seeking, rather than a ruminative, anger coping style.
Inspiring transformations through participation in drama for individuals with neuropalliative conditions
Authors: Fenech Anne 
Published: March 2010

Purpose: The aim of the service evaluation was to use an occupational science focus to describe the effects of drama with variable levels of sensory content and a potentially active, rather than a passive, participant role on engagement by individuals with neuropalliative conditions.
Method:
The service evaluation involved time sampled observations of engagement during a single session for each of the fourteen participants during a passive spectator role in the audience at a live drama, a potentially active interactive performance and a control condition.
Results: The observations
of engagement showed a significant difference between the engagement scores for the control condition and the drama.
Conclusions: Whilst drama appears to be satisfying their engagement it depends on the role offered to them (e.g. potentially active versus passive), on the level of sensory
stimulation offered and on the supporter to participant ratio available to facilitate their engagement.
You don't have to like them: Art, Tate Modern and learning
Authors: Weir Hannele 
Published: March 2010

The context for the article is a workshop that takes place at Tate Modern in London, with a focus on exploring violence. The material is drawn from two small-scale research projects. The participants, who come from a variety of occupations, observe and deal with violence in their work
in varying degrees. The rationale for the art gallery based session is that live visual works of art stimulate engagement in cognitive and emotional processes whilst exploring societal phenomena relevant to professional knowledge and development.
There are two main themes: the first focuses
on the art gallery visit as a means of learning, and the second is to consider the impact on students and whether learning in an art gallery might give insight into their practice.
Everybody's a Writer Theorizing screenwriting as creative labour
Authors: Conor Bridget 
Published: March 2010

This paper offers a theoretical agenda for a labourist analysis of screenwriting, and critically evaluates the marginal status of screenwriting within film production systems. On the one hand, screenwriting offers an exemplary case study of creative work in post-modernized film production
industries, work characterized by freelancing and multivalent working patterns, insecurity and hierarchization. Investigating screenwriting as creative labour also offers unique insights into an intensely industrial vocation; this requires a highly particular theorization of the contexts and
conditions of writers' working lives.
This paper draws on sociological analyses of creative production and utilizes a Foucauldian understanding of technologies of the self as this concept has been applied in the analysis of creative labour. This approach enables a critical examination of
particular aspects of screenwriting labour, including the rigidity of the industrial screenplay form and its pedagogical frameworks, the standardized mechanisms of control over screenwriting labour (such as inequitable collaboration and practices of multiple authorship), and the heady mix
of both creative fulfilment and punishment which characterizes this form of work.
Der EuGH und die Goldenen Aktien – zugleich ein Beitrag zur Dogmatik der Kapitalverkehrsfreiheit
Authors: Lippert André 
Published: March 2010

Schon mehrfach hat der Europäische Gerichtshof (EuGH) über die Vereinbarkeit von sogenannten Goldenen Aktien mit Gemeinschaftsrecht zu entscheiden gehabt, zuletzt im Fall des deutschen VW-Gesetzes. Anhand der Problematik der Goldenen Aktien lassen sich grundsätzliche Fragen der Auslegung und Anwendung der Grundfreiheiten durch den EuGH aufwerfen.
Die fortdauernde Aktualität dieses Themas für mündliche oder schriftliche Prüfungen im Europarecht ergibt sich nicht zuletzt aus der andauernden Auseinandersetzung mit der EU-Kommission über die Vereinbarkeit des neuen VW-Gesetzes mit den Vorgaben des EuGH.
Zur Person des Ausstellers einer Urkunde in Fällen offener Stellvertretung – Ein Beitrag zum Urkundenstrafrecht
Authors: Gerhold Sönke 
Published: March 2010

Die Definition des Urkundsbegriffs in all seinen Spielarten gehört zum Standardwissen der juristischen Ausbildung und muss in beiden Staatsexamen sicher beherrscht werden. Eine Urkunde ist nach der griffigsten Formel eine verkörperte Gedankenerklärung, die zum Beweis im Rechtsverkehr geeignet und bestimmt ist und ihren Aussteller erkennen lässt.
Wer ist nun aber der scheinbare Aussteller einer Urkunde, in der sich eine natürliche oder juristische Person offen vertreten lässt? Diese komplexe Frage soll im Folgenden anhand eines klausurtypischen Beispielsfalls beantwortet werden.
Constant Rate of Loading Test on Ultra-Soft Soil
Authors: Bo Myint Win , Choa Victor , Wong Kai Sin 
Published: March 2010

Abstract
The conventional consolidation test on ultra-soft soil takes a long time to complete due to the viscous effect in the early stage of compression. Instead of conducting the test until the end-of-primary (EOP) consolidation at each loading step, the testing time can be shortened if the test is carried out at a constant rate of loading (CRL). In this study the CRL tests were carried out at various loading rates. The settlement and pore pressure behavior were studied, and a suitable rate of loading (1 kPa/800 s) was determined. The proposed rate of loading is slightly slower than the rate of loading for natural clay suggested by others. The transition point between viscous stage and soil stage can be determined from the measured peak pore pressure. The compression indices, the large strain coefficient of consolidation, and the coefficient of permeability can also be determined from the CRL test with the proposed equations. This paper discussed the experimental test on ultra-soft soil at a CRL.
Mimetisches Handeln als Geflecht von actio und passio
Authors: Wulf Christoph 
Published: March 2010

ZusammenfassungIm mimetischen Handeln überlagern sich Aktivität und Passivität und bilden ein Geflecht, in dem diese Elemente nur analytisch unterscheidbar sind. Dies gilt für die antiken Konzeptionen von ”Mimesis“ wie für die Vorstellungen Benjamins und Adornos. In Untersuchungen zu den mimetischen Grundlagen des Sozialen lässt sich zeigen, dass praktisches Wissen und soziale Kompetenz weitgehend mimetisch erworben werden. Auch für ästhetische Erfahrungen oder für Erfahrungen von Alterität sind mimetische Prozesse konstitutiv. In ihnen wird Anähnlichung und Differenz erfahrbar.
Habitus jenseits von Struktur und Determinismus: Einschulung und Emotion
Authors: Eröss Gábor 
Published: March 2010

ZusammenfassungDer jeweilige Habitus der Eltern ist, auf der lokalen Ebene, im lokalen Kontext (Stadt/Gemeinde/Bezirk/Kiez), ein hic et nunc-Resultat der gegenseitigen Sinngebungen und Interaktionen. Der Habitus – als anthropologisches Konzept – ist kein Mittel der unaufhaltbaren Reproduktion, sondern eine Prädisposition für lokal produzierte und sinnstiftende Emotionen.Das Ritual der Einschulung beginnt – angesichts der freien Schulwahl – mit einem willentlichen Akt, schlägt dann in einen unwillkürlichen“ Erfahrungshorizont um (man wählt nicht, man wird ausgewählt oder ausgeschlossen, auf jeden Fall: kategorisiert) und führt – ganz auf der Ebene der körperlichen Wahrnehmung – entweder zu Leiden (das Scheitern der freien“ Schulwahl) oder zum Befreiungserlebnis (das Versprechen der sozialen Aufwärtsmobilität).
Refined Global Analysis ofBemisia tabaci(Hemiptera: Sternorrhyncha: Aleyrodoidea: Aleyrodidae) Mitochondrial Cytochrome Oxidase 1 to Identify Species Level Genetic Boundaries
Authors: Dinsdale A , Cook L , Riginos C , Buckley Y M , Barro P De 
Published: March 2010

AbstractIdentifying species boundaries within morphologically indistinguishable cryptic species complexes is often contentious. For the whitefly Bemisia tabaci (Gennadius) (Hemiptera: Sternorrhyncha: Aleyrodoidea: Aleyrodidae), the lack of a clear understanding about the genetic limits of the numerous genetic groups and biotypes so far identified has resulted in a lack of consistency in the application of the terms, the approaches used to apply them and in our understanding of what genetic structure within B. tabaci means. Our response has been to use mitochondrial gene cytochrome oxidase one to consider how to clearly and consistently define genetic separation. Using Bayesian phylogenetic analysis and analysis of sequence pairwise divergence we found a considerably higher number of genetic groups than had been previously determined with two breaks in the distribution, one at 11% and another at 3.5%. At &gt;11% divergence, 11 distinct groups were resolved, whereas at &gt;3.5% divergence 24 groups were identified. Consensus sequences for each of these groups were determined and were shown to be useful in the correct assignment of sequences of unknown origin. The 3.5% divergence bound is consistent with species level separations in other insect taxa and suggests that B. tabaci is a cryptic species composed of at least 24 distinct species. We further show that the placement of Bemesia atriplex (Froggatt) within the B. tabaci in group adds further weight to the argument for species level separation within B. tabaci. This new analysis, which constructs consensus sequences and uses these as a standard against which unknown sequences can be compared, provides for the first time a consistent means of identifying the genetic bounds of each species with a high degree of certainty.
Perfluorooctane Sulfonic Acid Contamination Reduced Fitness in Drosophila hydei (Diptera: Drosophilidae)
Authors: Gossum H Van , Audenaert B , Bruyn L De 
Published: March 2010

Abstract
Studies on the effects of perfluorooctane sulfonic acid (PFOS) exposure on terrestrial invertebrates are very scarce. Here, we quantified the effects of PFOS on the number of offspring for two generations of Drosophila hydei Sturtevant 1921 (Diptera: Drosophilidae) reared in the laboratory. The first generation was exposed to a range of PFOS concentrations from 5 to 5,000 ng/ml and a control through their diet. For the second generation, offspring of the 50 ng/ml PFOS treatment and the control were further reared in a PFOS-free environment. For the first generation, the number of offspring decreased with increasing levels of PFOS contamination. Although the second generation was not exposed to PFOS, we still observed a reduction in the number of offspring when the parental flies were exposed to 50 ng/ml PFOS. The results of the current study indicate that the sensitivity to PFOS of D. hydei is several magnitudes higher than of the other terrestrial invertebrate species tested so far. This sensitivity falls within the concentration range detected in its natural food.
Survey for Winter Moth (Lepidoptera: Geometridae) in Northeastern North America with Pheromone-Baited Traps and Hybridization with the Native Bruce Spanworm (Lepidoptera: Geometridae)
Authors: Elkinton Joseph S , Boettner George H , Sremac Marinko , Gwiazdowski Rodger , Hunkins Roy R , Callahan Julie , Scheufele Susan B , Donahue Charlene P , Porter Adam H , Khrimian Ashot , Whited Brenda M , Campbell Nichole K 
Published: March 2010

AbstractWe used pheromone-baited traps to survey the distribution of winter moth, Operophtera brumata (L.) (Lepidoptera: Geometridae), a new invasive defoliator from Europe in eastern New England. The traps also attracted Bruce spanworm, Operophtera bruceata (Hulst) (Lepidoptera: Geometridae), native to North America. We distinguished between the two species by examining male genitalia and sequencing the mitochondrial cytochrome oxidase subunit 1 (COI) gene, the DNA barcoding region. In 2005, we recovered winter moths at sites stretching from eastern Long Island, southeastern Connecticut, all of Rhode Island, eastern Massachusetts, coastal New Hampshire, and southern coastal Maine. At sites further west and north we captured only Bruce spanworm. In 2006, we confirmed that both winter moth and Bruce spanworm are present in Nova Scotia and in coastal Maine, but only Bruce spanworm was recovered in coastal New Brunswick, Canada; Pennsylvania; Vermont; or Quebec City, Canada. In 2007, we collected Bruce spanworm, but no winter moths, in New Brunswick and the interior areas of Maine, New Hampshire, and New York. Winter moth and Brace spanworm differed in the COI sequence by 7.45% of their nucleotides. The prevalence of intermediate genitalia in the zone of overlap suggested that hybridization between the two species may be occurring. To confirm the presence of hybrids, we sequenced the nuclear gene, glucose-6phosphate dehydrogenase (G6PD). We identified six nucleotides that routinely distinguished winter moth and Bruce spanworm, of which three were always diagnostic. We showed that eggs produced by hybridizing the two species in the laboratory contained copies of both species at these six sites. We found that most of the moths collected in the field with intermediate genitalia had winter moth CO1 and G6PD sequences and thus were not hybrids (or at least F1 hybrids). We found three hybrids out of 158 moths with intermediate genitalia in the region where both species were caught. We conclude that hybrids occur in nature, but are not as common as previously reported. Introgression of genes between the two species may still be significant.
Geographic Variation in Size and Oviposition Depths ofRomalea microptera(Orthoptera: Acrididae) is Associated with Different Soil Conditions
Authors: Herrmann Dustin L , Ko Alexander E , Bhatt Surabhi , Jannot Jason E , Juliano Steven A 
Published: March 2010

AbstractIntraspecific geographic variation in morphology and behavior can be indicative of populations that are adapted to local environmental conditions. Heterogeneity in the abiotic environment, such as soil conditions, can be an important driver of local adaptation. In south Florida, mean body sizes in populations of the lubber grasshopper Romalea microptera (Beauvois) (Orthoptera: Acrididae), increase from west to east. We tested how body size variation, population origin, and soil physical characteristics are associated with oviposition depth in the soil. In a laboratory experiment with homogeneous soil conditions, size-corrected oviposition depth (analysis of covariance) differed among three populations: females from a western population oviposited at the shallowest depths; females from an eastern population oviposited the deepest; and a central population oviposited at intermediate depths. A similar pattern also was observed in two field experiments conducted on two additional populations not used in the laboratory experiments. In addition, size-corrected oviposition depth in the field experiments declined with increasing soil compaction for both populations but the decline was significantly steeper for the eastern population. High soil moisture yielded significantly shallower size-corrected oviposition depth only for the eastern population. Female size was positively related to oviposition depth in both field experiments, but the relationship between female size and oviposition depth did not differ among populations (i.e., equal slopes). We suggest that local soil conditions might be an important selection pressure and behavioral cue in determining oviposition depth. Choice of vertical position of the egg pod within the soil is discussed as one possible mechanism by which females can influence offspring viability.
Approval Summary: Imatinib Mesylate in the Adjuvant Treatment of Malignant Gastrointestinal Stromal Tumors
Authors: Cohen Martin H. , Cortazar Patricia , Justice Robert , Pazdur Richard 
Published: March 2010

Abstract
On December 19, 2008, the U.S. Food and Drug Administration approved imatinib mesylate tablets for oral use (Gleevec®; Novartis Pharmaceuticals Corporation, East Hanover, NJ) for the adjuvant treatment of adult patients following complete gross resection of Kit+ (CD117+) gastrointestinal stromal tumor (GIST).
A randomized, double-blind, placebo-controlled study enrolling 713 patients was submitted. The primary objective of the clinical trial was to compare the recurrence-free survival (RFS) intervals of the two groups. Overall survival (OS) was a secondary endpoint. Eligible patients were ≥18 years of age with a histological diagnosis of GIST (Kit+), resected tumor size ≥3 cm, and a complete gross resection within 14–70 days prior to registration. Imatinib, 400 mg orally, was administered once daily for 1 year.
The study was terminated after completion of the third protocol-specified interim analysis. At that time, 100 RFS events were confirmed by a blinded central independent review. With a median follow-up of 14 months, 30 RFS events were observed in the imatinib group and 70 were observed in the placebo group (hazard ratio, 0.398; 95% confidence interval, 0.259–0.610; two-sided p-value &lt; .0001). OS results are immature.
Most patients in both groups experienced at least one adverse reaction, and 31% of the imatinib group and 18% of the placebo group experienced grade ≥3 adverse reactions. The most frequently reported adverse reactions (≥20%) were diarrhea, fatigue, nausea, edema, decreased hemoglobin, rash, vomiting, and abdominal pain. Drug was discontinued for adverse reactions in 17% and 3% of the imatinib and placebo-treated patients, respectively.
GAGES: A stream gage database for evaluating natural and altered flow conditions in the conterminous United States
Authors: Falcone James A. , Carlisle Daren M. , Wolock David M. , Meador Michael R. 
Published: March 2010

Stream flow is a controlling element in the ecology of rivers and streams. Knowledge of the natural flow regime facilitates the assessment of whether specific hydrologic attributes have been altered by humans in a particular stream and the establishment of specific goals for stream‐flow restoration. Because most streams are ungaged or have been altered by human influences, characterizing the natural flow regime is often only possible by estimating flow characteristics based on nearby stream gages of reference quality, i.e., gaged locations that are least disturbed by human influences. The ability to evaluate natural stream flow, that which is not altered by human activities, would be enhanced by the existence of a nationally consistent and up‐to‐date database of gages in relatively undisturbed watersheds.As part of a national effort to characterize stream‐flow effects on ecological condition, data for 6785 U.S. Geological Survey (USGS) stream gages and their upstream watersheds were compiled. The sites comprise all USGS stream gages in the conterminous United States with at least 20 years of complete‐year flow record from 1950–2007, and for which watershed boundaries could reliably be delineated (median size = 578 km2). Several hundred watershed and site characteristics were calculated or compiled from national data sources, including environmental features (e.g., climate, geology, soils, topography) and anthropogenic influences (e.g., land use, roads, presence of dams, or canals).In addition, watersheds were assessed for their reference quality within nine broad regions for use in studies intended to characterize stream flows under conditions minimally influenced by human activities. Three primary criteria were used to assess reference quality: (1) a quantitative index of anthropogenic modification within the watershed based on GIS‐derived variables, (2) visual inspection of every stream gage and drainage basin from recent high‐resolution imagery and topographic maps, and (3) information about man‐made influences from USGS Annual Water Data Reports. From the set of 6785 sites, we identified 1512 as reference‐quality stream gages. All data derived for these watersheds as well as the reference condition evaluation are provided as an online data set termed GAGES (geospatial attributes of gages for evaluating stream flow).The complete data sets corresponding to abstracts published in the Data Papers section of the journal are published electronically in Ecological Archives at 〈http://esapubs.org/archive〉. (The accession number for each Data Paper is given directly beneath the title.)