bluuebunny/crossref_metadata_2025_split huggingface dataset:
Imatinib has adverse effect on growth in children with chronic myeloid leukemia
Authors: Bansal Deepak , Shava Upender , Varma Neelam , Trehan Amita , Marwaha R.K. 
Published: November 2011

AbstractBackgroundLong‐term adverse effects of Imatinib in children with chronic myeloid leukemia (CML) are uncertain. The aim was to study the effect of imatinib on growth in children with CML.ProcedureChildren ≤13 years of age at diagnosis were enrolled retrospectively, from 2004 to 2011, from a single center in India. Patients who received imatinib for >1 year were included for growth assessment. Height standard deviation scores (SDS) were derived from WHO‐AnthroPlus, a global growth monitoring tool.ResultsThirty‐four children received imatinib. Twenty children fulfilled the criteria for assessment of growth. Median age was 10 years (range: 2–13). Of 20 children, 13 were prepubertal at commencement of imatinib. The mean duration of imatinib in 20 children was 61.3 ± 16.2 months (range: 31–83). No patient was treated with a second‐generation tyrosine kinase inhibitor or a stem cell transplant. Highly significant reduction in height SDS's was observed (P = 0.002 at 5th year). Children who started imatinib therapy after the onset of puberty were immune to this adverse effect (P = 0.448 and 0.003 at 5th year of treatment for pubertal and prepubertal children, respectively). The 5‐year survival probability of 33 children who received imatinib in chronic phase was 80% with a median survival time of 60 months (mean: 70.2; 95% CI: 60–80.5).ConclusionsGrowth retardation is a significant adverse effect of imatinib in children with CML. The failure to gain appropriate height was most discernible when imatinib was initiated in the prepubertal period. Etiology and remedial measures need to be investigated. Pediatr Blood Cancer 2012;59:481–484. © 2011 Wiley Periodicals, Inc.
Treatment of pharyngeal non‐Hodgkin lymphoma in a patient with Wiskott‐Aldrich syndrome
Authors: Coccia Paola , Mastrangelo Stefano , Ruggiero Antonio , Scalzone Maria , Rosolen Angelo , Maurizi Palma , Riccardi Riccardo 
Published: November 2011

AbstractWiskott‐Aldrich syndrome (WAS) is characterized by primary immunodeficiency, thrombocytopenia and eczema. Patients with WAS have an increased risk to develop tumors. Non‐Hodgkin lymphoma (NHL) represents the most common malignancy occurring in WAS‐affected patients, diffuse‐large‐B‐cell lymphoma is the most frequently encountered variant. We describe a case of a patient with WAS and NHL in the pharynx, an atypical tumor site presentation. The patient was successfully treated with a reduced dose chemotherapy regimen plus anti‐CD20 monoclonal antibody. He is in complete remission 3 years from the start of treatment. Pediatr Blood Cancer 2012;59:318–319. © 2011 Wiley Periodicals, Inc.
Ionic polymers with tunable liquid‐crystalline properties
Authors: Šebenik Gorazd , Huskić Miroslav , Žagar Ema , Žigon Majda 
Published: November 2011

AbstractSide‐chain polyesters were synthesized from N‐octyl‐, N‐dodecyl‐ or N‐hexadecyl‐diethanolamine and succinic acid anhydride. These polyesters were then transformed into polyester hydrochlorides by protonation of the amino groups using different amounts of HCl (20–100 mol%). Above 60 mol% the reaction is not quantitative and a degree of protonation of up to 88% is obtained. The structures of the synthesized polyesters and their hydrochlorides were determined by 1H nuclear magnetic resonance spectroscopy. The thermal properties of the synthesized polyesters and their hydrochlorides were also studied using differential scanning calorimetry in relation to the side‐chain length and the degree of polyester protonation. The polyester with octyl side chains and its hydrochlorides were amorphous liquids at room temperature, while the polyester and polyester hydrochlorides with hexadecyl side chains formed a smectic crystalline phase, SmB, or its tilted analogues. The polyester with a dodecyl side chain was also an amorphous liquid at room temperature, while its hydrochlorides with various degrees of protonation were smectic liquid crystals, as determined by X‐ray diffraction. By simply varying the degree of protonation the liquid crystal isotropization temperature was increased from 32 °C to 82 °C. Copyright © 2011 Society of Chemical Industry
Thin film solar cell with 8.4% power conversion efficiency using an earth‐abundant Cu2ZnSnS4 absorber
Authors: Shin Byungha , Gunawan Oki , Zhu Yu , Bojarczuk Nestor A. , Chey S. Jay , Guha Supratik 
Published: November 2011

ABSTRACTUsing vacuum process, we fabricated Cu2ZnSnS4 solar cells with 8.4% efficiency, a number independently certified by an external, accredited laboratory. This is the highest efficiency reported for pure sulfide Cu2ZnSnS4 prepared by any method. Consistent with literature, the optimal composition is Cu‐poor and Zn‐rich despite the precipitation of secondary phases (e.g., ZnS). Despite a very thin absorber thickness (~600 nm), a reasonably good short‐circuit current was obtained. Time‐resolved photoluminescence measurements suggest a minority carrier‐diffusion length on the order of several hundreds of nanometers and relatively good collection of photo‐carriers across the entire absorber thickness. Copyright © 2011 John Wiley & Sons, Ltd.
Factor structure of child behavior scale scores in peruvian preschoolers
Authors: Meyer Erin L. , Schaefer Barbara A. , Soto Cesar Merino , Simmons Crystal S. , Anguiano Rebecca , Brett Jeremy , Holman Alea , Martin Justin F. , Hata Heidi K. , Roberts Kimberly J. , Mello Zena R. , Worrell Frank C. 
Published: November 2011

AbstractBehavior rating scales aid in the identification of problem behaviors, as well as the development of interventions to reduce such behavior. Although scores on many behavior rating scales have been validated in the United States, there have been few such studies in other cultural contexts. In this study, the structural validity of scores on a Spanish translation of the six‐factor Child Behavior Scale (CBS) was assessed in a sample of 265 Peruvian preschool children who ranged from 2 to 6 years in age. Exploratory factor analysis yielded a four‐factor structure, and reliability estimates for scores on the four factors were adequate. The authors suggest replicating the study and examining the utility of CBS scores in predicting future problem behaviors in this population. © 2011 Wiley Periodicals, Inc.
Problem analysis: Examining the selection and evaluation of data during problem‐solving consultation
Authors: Newell Markeda L. , Newell Terrance S. 
Published: November 2011

AbstractThe purpose of this study was to analyze how school psychologists engaged in problem analysis during problem‐solving consultation. Five aspects of the problem analysis process were examined: 1) the types of questions participants asked during problem identification, 2) the types of data participants requested, 3) the frequency of requests for each type of data, 4) the use of multiple methods and sources of data across multiple domains, and 5) the criteria used to interpret the data. Four school psychologists were recruited to each complete three fictional consultation cases within a computer‐simulated environment. A qualitative case study method was used. The results of this study revealed how school psychologists used theory, a multidimensional assessment framework, and self‐referent data to analyze a problem. Implications for future research are discussed. © 2011 Wiley Periodicals, Inc.
Predicting teacher commitment: The impact of school climate and social–emotional learning
Authors: Collie Rebecca J. , Shapka Jennifer D. , Perry Nancy E. 
Published: November 2011

AbstractThe aim of this study was to investigate whether school climate and social–emotional learning impact teacher commitment. The sample included 664 public schoolteachers from British Columbia and Ontario in Canada. Participants completed an online questionnaire about teacher commitment, school climate, and social–emotional learning. Binary logistic regression analyses showed that positive school climates significantly predicted three forms of teacher commitment: greater general professional commitment, future professional commitment, and organizational commitment. Of the school climate variables, student relations and collaboration among staff predicted commitment. In addition, stronger beliefs and integration of social–emotional learning predicted two types of teacher commitment: greater general professional commitment and organizational commitment. Of the social–emotional learning variables, the support and promotion of a social–emotional learning culture across the school and comfort with and regular implementation of social–emotional learning in the classroom predicted greater teacher commitment. Implications for practice and research are discussed. © 2011 Wiley Periodicals, Inc.
Clinical aspects of neurodegenerative diseases – 15th HUPO BPP Workshop April 8–9, 2011, Bochum, Germany
Authors: Gröttrup Bernd , Böckmann Miriam , Marcus Katrin , Wiltfang Jens , Grinberg Lea T. , Meyer Helmut E. , Park Young M. 
Published: November 2011

AbstractThe HUPO Brain Proteome Project (HUPO BPP) held its 15th workshop in Bochum, Germany, from April 8th to 9th, 2011 directly after the Proteomic Forum 2011 in Berlin. Like on every spring workshop, the focus was more on clinical aspects, so that especially clinicians participated in this workshop.
Enabling BioSharing – a report on the Annual Spring Workshop of the HUPO‐PSI April 11–13, 2011, EMBL‐Heidelberg, Germany
Authors: Orchard Sandra , Albar Juan Pablo , Deutsch Eric W. , Eisenacher Martin , Vizcaíno Juan A. , Hermjakob Henning 
Published: November 2011

AbstractThe Annual Spring workshop of the HUPO‐PSI was this year held at the EMBL International Centre for Advanced Training (EICAT) in Heidelberg, Germany. Delegates briefly reviewed the successes of the group to date. These include the wide spread implementation of the molecular interaction data exchange formats, PSI‐MI XML2.5 and MITAB, and also of mzML, the standard output format for mass spectrometer output data. These successes have resulted in enhanced accessibility to published data, for example the development of the PSICQUIC common query interface for interaction data and the development of databases such as PRIDE to act as public repositories for proteomics data and increased biosharing, through the development of consortia, for example IMEx and ProteomeXchange which will both share the burden of curating the increasing amounts of data being published and work together to make this more accessible to the bench scientist. Work then started over the three days of the workshop, with a focus on advancing the draft format for handling quantitative mass spectrometry data (mzQuantML) and further developing TraML, a standardized format for the exchange and transmission of transition lists for SRM experiments.
Magnetism, optical absorbance, and 19F NMR spectra of nafion films with self‐assembling paramagnetic networks
Authors: Levin E. M. , Chen Q. , Bud'ko S. L. 
Published: November 2011

AbstractMagnetization, optical absorbance, and 19F NMR spectra of Nafion transparent films as received and doped with Mn2+, Co2+, Fe2+, and Fe3+ ions with and without treatment in 1H‐1,2,4‐triazole (trz) have been studied. Doping of Nafion with Fe2+ and Co2+ and their bridging to nitrogen of triazole yields a hybrid self‐assembling paramagnetic system that exhibits interesting magnetic and optical properties. These include spin crossover phenomena between high‐spin (HS) and low‐spin (LS) states in Nafion‐Fe2+‐trz and Nafion‐Co2+‐trz accompanied by thermochromic effects in the visible range induced by temperature. A large shift of the magnetization curve induced by a magnetic field in the vicinity of the HS ↔ LS, ∼220 K, observed for Nafion‐Fe2+‐trz has a rate of ∼6 K/kOe, which is about three orders of magnitude larger than that in bulk spin crossover Fe2+ materials. Selective response of 19F NMR signals on doping with paramagnetic ions demonstrates that NMR can be used as spatially resolved method to study Nafion film with paramagnetic network. Both chemical shift and width of 19F NMR signals show that SO groups of Nafion, Fe or Co ions, and nitrogen of triazole are bonded whereas they form a spin crossover system. Based on a model of nanosize cylinders proposed for Nafion [K. Schmidt‐Rohr and Q. Chen, Nat Mater (2008), 75], we suggest that paramagnetic ions are located inside these cylinders, forming self‐assembling magnetically and optically active nanoscale networks. © 2011 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 50: 129–138, 2012
Effect of the spray application technique on the deposition of entomopathogenic nematodes in vegetables
Authors: Brusselman Eva , Beck Bert , Pollet Sabien , Temmerman Femke , Spanoghe Pieter , Moens Maurice , Nuyttens David 
Published: November 2011

AbstractBACKGROUND: The present study compared entomopathogenic nematode delivery at the base of savoy cabbage and cauliflower, at the lower side of savoy cabbage and cauliflower leaves and in leek stems and the ground deposition using a five‐nozzle spray boom equipped with an ISO 08 flat fan, an air induction flat fan and Twinjet spray nozzles. Additionally, an air support system and a row application system were evaluated.RESULTS: Approximately 40% of the applied nematodes did not reach the foot of the cabbage plants. The use of an air support system or a row application system improved nematode deposition at the savoy cabbage base. Relative nematode deposition on the lower side of savoy cabbage leaves was 27.20%, while only 2.64% of the applied nematodes reached the lower side of cauliflower leaves. After spraying leek with a standard boom, a low relative nematode deposition (26.64%) was measured in the leek stem. Nozzle type affected the distribution of nematodes in droplet spots.CONCLUSION: Nozzle type has a minor effect on the number of entomopathogenic nematodes delivered on difficult‐to‐reach targets. The use of modified spray application techniques directing the spray to the target site are necessary to increase the chances of contact of entomopathogenic nematodes with their target. Copyright © 2011 Society of Chemical Industry
Identifying the presence of neonicotinoidresistant peach‐potato aphid (Myzus persicae) in the peach‐growing regions of southern France and northern Spain
Authors: Slater Russell , Paul Verity Laura , Andrews Melanie , Garbay Michel , Camblin Philippe 
Published: November 2011

AbstractBACKGROUND: The neonicotinoid class of insecticides is a key component of pest management strategies used by stone fruit producers in Europe. Neonicotinoids are currently one of the most important tools for control of the peach‐potato aphid (Myzus persicae). Overreliance on neonicotinoids has led to the development of resistance through a combination of metabolic and target‐site resistance mechanisms in individual aphids. A resistance monitoring project was conducted by Syngenta in 2010 to determine the resistance status of M. persicae populations collected from France and Spain, and to determine the frequency of the target‐site mutation in those populations.RESULTS: Resistance monitoring suggests that resistance to neonicotinoids is relatively widespread in populations of M. persicae collected from peach orchards in the Languedoc‐Roussillon, Provence‐Alpes‐Cote d'Azur and Rhone‐Alpes regions of France, and resistance can be associated with the frequency of the target‐site mutation (R81T). The R81T mutation in its heterozygous form is also present in Spanish populations and is associated with neonicotinoid resistance.CONCLUSION: The widespread nature of neonicotinoid resistance in southern France and the potential for resistance development in northern Spain highlight the need for a coordinated management strategy employing insecticides with different modes of action to reduce the selection pressure with neonicotinoids. Copyright © 2011 Society of Chemical Industry
Strong resistance to the fungicide fenhexamid entails a fitness cost in Botrytis cinerea, as shown by comparisons of isogenic strains
Authors: Billard Alexis , Fillinger Sabine , Leroux Pierre , Lachaise Hélène , Beffa Roland , Debieu Danièle 
Published: November 2011

AbstractBACKGROUND: Fenhexamid, a sterol biosynthesis inhibitor effective against Botrytis, inhibits the 3‐ketoreductase (Erg27) involved in C‐4 demethylation. Several fenhexamid‐resistant phenotypes have been detected in Botrytis cinerea populations from French vineyards. The field isolates with the highest resistance levels display amino acid changes in Erg27 (F412S, F412I or F412V).RESULTS: Fenhexamid‐resistant mutants were generated by site‐directed mutagenesis of the erg27 gene in a sensitive recipient strain to overcome the impact of different genetic backgrounds. The wild‐type erg27 allele was replaced by the three mutated alleles (erg27F412S/I/V) by homologous recombination. These isogenic strains were shown to be fenhexamid‐resistant and were used to quantify the impact of F412 mutations on fungal fitness. Several parameters, including radial growth, the production of sclerotia and conidia, freezing resistance and aggressiveness, were quantified in laboratory conditions. Analysis of variance demonstrated significant differences between the mutant and parental strains for some characters. In particular, the mutants grew more slowly than the wild‐type strain and displayed variations in the production of sclerotia and conidia with temperature and susceptibility to freezing.CONCLUSIONS: The results highlight a moderate but significant impact of F412 mutations on the survival capacity of B. cinerea strains displaying high levels of resistance to fenhexamid in laboratory conditions, potentially limiting their dispersal and persistence, particularly in terms of overwintering, in field conditions. Copyright © 2011 Society of Chemical Industry
Charge separation in organic semiconductor blends studied by electrical in situ characterization during film growth
Authors: Beu Max , Dragässer André , Keil Christopher , Schlettwein Derck 
Published: November 2011

AbstractThe influence of the substrate temperature during film growth as well as annealing of films subsequent to preparation was studied by in situ measurements of conduction and photoconduction of molecular blends of phthalocyaninatocopper (PcCu) and buckminster‐fullerene (C60). The findings are discussed in context of structural and morphological changes observed in scanning electron microscopy (SEM) and UV/Vis transmission measurements. Deposition of bulk heterojunctions (BHJs) at elevated substrate temperature featured improved percolation pathways leading to increased conductivity, photoconductivity, and exciton dissociation yield. At low concentrations of PcCu in C60 electron trapping by light‐induced hole states in PcCu was observed.
Magnetism of DyNi2B2C nanoparticle investigated with a quantum simulation model
Authors: Liu Z.‐S. , Diviš M. , Sechovský V. 
Published: November 2011

AbstractWe employed a quantum simulation model and a new computational algorithm we developed recently to study the magnetism of an assumed DyNi2B2C nanoparticle consisting of an inner core and an outer shell of complicated crystal and magnetic structures. Our theoretical results obtained with the new simulation model are reasonable physically, and the computational speed with the new algorithm is faster than the micromagnetism and Monte–Carlo approaches, which have been popularly utilized by most researchers worldwide for many years.
Circular polariscopic measurement of a semi‐insulating SiC wafer for evaluating strains and its relation with Raman spectra: Superiority to monochromatic Lang X‐ray topography
Authors: Takeuchi Hideo 
Published: November 2011

AbstractWe have explored the effectiveness of applying the circular polariscopic measurement to the mapping of the strains in a semi‐insulating 6H‐SiC wafer. Initially, monochromatic Lang X‐ray topography, which is regarded as a fundamental evaluation technique for wafers, is applied. In the monochromatic Lang X‐ray topograph, the disappearance of the images is found in various areas, which suggests that the monochromatic Lang X‐ray topographic measurement is not almighty. Next, we apply the circular polariscopic measurement, which is sensitive to strains through the photoelastic effect. The brightness of the circular polariscopic wafer map reveals that the inhomogeneous distribution of the strains. The observed phenomenon indicates that the magnitude of the crystal‐plane distortion is too strong to apply monochromatic Lang X‐ray topography. The presence of the relatively large strains is confirmed from the fact that the forbidden reflection lines are observed in the θ ‐2θ X‐ray diffraction pattern. We also measure the Raman spectra of the several region of the wafer to evaluate the stress from the phonon frequency shift. The maximum stress is estimated to be ∼490 MPa. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Time‐resolved detection of many‐particle hole states in InAs/GaAs quantum dots using a two‐dimensional hole gas up to 77 K
Authors: Nowozin T. , Marent A. , Bimberg D. , Beckel A. , Marquardt B. , Lorke A. , Geller M. 
Published: November 2011

AbstractWe demonstrate the detection of many‐particle hole states in self‐organized InAs/GaAs quantum dots (QDs) using an adjacent two‐dimensional hole gas (2DHG) as detector for temperatures up to 77 K. capacitance‐voltage (C‐V) measurements as well as time‐resolved current measurements in the 2DHG resolve a structure of six distinct peaks which are related to the many‐particle hole states in the QD ensemble. The time constants of the capture and emission processes for each individual many‐particle hole state are extracted and the underlying emission processes are identified. An equivalent circuit model yields the gate voltage depedent lever‐arm and the level‐splittings of the many‐particle hole states. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Hafnium oxide passivation of InGaAs/InP heterostructure bipolar transistors by electron beam evaporation
Authors: Driad R. , Schmidt R. , Kirste L. , Loesch R. , Mikulla M. , Ambacher O. 
Published: November 2011

AbstractIn this contribution, we investigate the passivation of InGaAs/InP heterostructures using plasma assisted e‐beam evaporated hafnium oxide (HfO2). The microstructure and optical properties of the HfO2 layers are first examined by X‐ray reflectivity and spectroscopic ellipsometry on Si substrates. The current gain and breakdown voltage of InGaAs/InP heterostructure bipolar transistors (HBTs) have subsequently been used to evaluate the impact and efficiency of the e‐beam evaporated HfO2 passivation layers. The results from these structures have been contrasted with data from similar samples encapsulated with SiO2 using conventional plasma enhanced chemical vapor deposition. The HfO2 passivated InGaAs/InP HBTs show comparable current gains as compared to unpassivated structures. More importantly, in contrast to SiO2‐PECVD devices, the common emitter characteristics of HfO2 passivated HBTs show no degradation in device breakdown voltage. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Modelling of passive mode‐locking in InAs quantum‐dot lasers with tapered gain section
Authors: Rossetti Mattia , Xu Tianhong , Bardella Paolo , Montrosset Ivo 
Published: November 2011

AbstractWe propose a computationally efficient approach for the simulation and design of index‐guided quantum‐dot (QD) passively mode‐locked lasers with tapered gain section; the method is based on the combination of simulations based on a finite difference beam‐propagation‐method and dynamic simulations of mode‐locking via a multi‐section delayed differential equation model. The impact of varying the taper full angle on the pulse duration and peak power is investigated; simulations show that a correct choice of this parameter enables the generation of sub‐picosecond optical pulses with peak power exceeding 5 W (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)