bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Five‐Session CAT’ Consultancy: Using CAT to Guide Care Planning with People Diagnosed with Personality Disorder within Community Mental Health Teams
Authors: Carradice Angela 
Published: August 2012

There are a number of clients that mental health teams (CMHTs) struggle to help. This group often have some form of personality disorder diagnosis. All workers can experience the client's presentation as challenging and this sometimes results in unhelpful repeated patterns between clients and services. Difficulties for this client group include abrupt state shifting, powerful dynamics, difficult/complex relationships with (often numerous) services, symptoms of dissociation, difficulties with emotional regulation and self abuse. Some people with these difficulties can present to services with a number of factors that mean it is hard to work helpfully with them such as having unstable and chaotic lives, experiencing significant ongoing risks from others and often coping day to day by using a variety of harmful strategies such as self‐harm, planning suicide and a significant amount of alcohol and/or drug use. The group of clients who experience these difficulties are often assessed as not being able to benefit from individual psychotherapy in the community. Five‐session cognitive analytic therapy (CAT) consultancy has been developed as a method to work jointly with mental health workers and their clients to develop a map to understanding their current difficulties, patterns of coping and to guide care planning. This paper describes the steps of ‘five‐session CAT’ consultancy and the skills involved. Copyright © 2012 John Wiley & Sons, Ltd.Key Practitioner MessagesNewly evolved approach using CAT to help guide CMHT care planningFor people with a diagnosis of personality disorderWho seem unsuitable for individual psychotherapyBecause of the nature of their difficulties, mental health teams find such clients difficult to help
Controlling the Adsorption Enthalpy of CO2 in Zeolites by Framework Topology and Composition
Authors: Grajciar Lukáš , Čejka Jiří , Zukal Arnošt , Otero Areán Carlos , Turnes Palomino Gemma , Nachtigall Petr 
Published: August 2012

AbstractZeolites are often investigated as potential adsorbents for CO2 adsorption and separation. Depending on the zeolite topology and composition (Si/Al ratio and extra‐framework cations), the CO2 adsorption heats at low coverages vary from −20 to −60 kJ mol−1, and with increasing surface coverage adsorption heats either stay approximately constant or they quickly drop down. Experimental adsorption heats obtained for purely siliceous porous solids and for ion‐exchanged zeolites of the structural type MFI, FER, FAU, LTA, TUN, IMF, and ‐SVR are discussed in light of results of periodic density functional theory calculations corrected for the description of dispersion interactions. Key factors influencing the stability of CO2 adsorption complexes are identified and discussed at the molecular level. A general model for CO2 adsorption in zeolites and related materials is proposed and data reported in literature are evaluated with regard to the proposed model.
Joint subcarrier and power allocation with fairness in uplink OFDMA systems based on ant colony optimization
Authors: Wang Fei , Liao Xiaofeng , Guo Songtao , Huang Hongyu 
Published: August 2012

SUMMARYOne of the key problems in uplink orthogonal frequency division multiple access systems is to efficiently and fairly allocate subcarriers and powers. However, most existing work has not sufficiently taken into account fairness when allocating these resources so that subcarriers cannot be fairly allocated among users with different channel conditions. To overcome this shortcoming, we first present an optimization framework with fairness, which aims to fairly allocate subcarriers among different users and to distribute the transmission power of each user over the assigned subcarriers. Here, the fairness is guaranteed by associating each user with a utility function and placing a lower limit on the number of subcarriers assigned. In particular, different from previous work, utility functions are allowed to be nonconcave and nondifferentiable so that our framework can be suitable for resource allocation for real‐time applications. Furthermore, an iterative algorithm based on the ant colony optimization is proposed, according to which subcarriers can be efficiently and fairly allocated among different users. Simulation results verify the convergence of our algorithm. In addition, our algorithm outperforms several other algorithms in terms of the fairness of resource allocation. Copyright © 2012 John Wiley & Sons, Ltd.
Netrin‐1 is required for efficient neural tube closure
Authors: Kee Nigel , Wilson Nicole , Key Brian , Cooper Helen M. 
Published: August 2012

AbstractDuring neural tube formation, neural plate cells migrate from the lateral aspects of the dorsal surface towards the midline. Elevation of the lateral regions of the neural plate produces the neural folds which then migrate to the midline where they fuse at their dorsal tips, generating a closed neural tube comprising an apicobasally polarized neuroepithelium. Our previous study identified a novel role for the axon guidance receptor neogenin in Xenopus neural tube formation. We demonstrated that loss of neogenin impeded neural fold apposition and neural tube closure. This study also revealed that neogenin, via its interaction with its ligand, RGMa, promoted cell–cell adhesion between neural plate cells as the neural folds elevated and between neuroepithelial cells within the neural tube. The second neogenin ligand, netrin‐1, has been implicated in cell migration and epithelial morphogenesis. Therefore, we hypothesized that netrin‐1 may also act as a ligand for neogenin during neurulation. Here we demonstrate that morpholino knockdown of Xenopus netrin‐1 results in delayed neural fold apposition and neural tube closure. We further show that netrin‐1 functions in the same pathway as neogenin and RGMa during neurulation. However, contrary to the role of neogenin‐RGMa interactions, neogenin‐netrin‐1 interactions are not required for neural fold elevation or adhesion between neuroepithelial cells. Instead, our data suggest that netrin‐1 contributes to the migration of the neural folds towards the midline. We conclude that both neogenin ligands work synergistically to ensure neural tube closure. © 2012 Wiley Periodicals, Inc., 2013
Geographic mosaic of symbiont selectivity in a genus of epiphytic cyanolichens
Authors: Fedrowitz Katja , Kaasalainen Ulla , Rikkinen Jouko 
Published: August 2012

AbstractIn symbiotic systems, patterns of symbiont diversity and selectivity are crucial for the understanding of fundamental ecological processes such as dispersal and establishment. The lichen genus Nephroma (Peltigerales, Ascomycota) has a nearly cosmopolitan distribution and is thus an attractive model for the study of symbiotic interactions over a wide range of spatial scales. In this study, we analyze the genetic diversity of Nephroma mycobionts and their associated Nostoc photobionts within a global framework. The study is based on Internal Transcribed Spacer (ITS) sequences of fungal symbionts and tRNALeu (UAA) intron sequences of cyanobacterial symbionts. The full data set includes 271 Nephroma and 358 Nostoc sequences, with over 150 sequence pairs known to originate from the same lichen thalli. Our results show that all bipartite Nephroma species associate with one group of Nostoc different from Nostoc typically found in tripartite Nephroma species. This conserved association appears to have been inherited from the common ancestor of all extant species. While specific associations between some symbiont genotypes can be observed over vast distances, both symbionts tend to show genetic differentiation over wide geographic scales. Most bipartite Nephroma species share their Nostoc symbionts with one or more other fungal taxa, and no fungal species associates solely with a single Nostoc genotype, supporting the concept of functional lichen guilds. Symbiont selectivity patterns within these lichens are best described as a geographic mosaic, with higher selectivity locally than globally. This may reflect specific habitat preferences of particular symbiont combinations, but also the influence of founder effects.
The role of turbulence in the hydraulic environment of benthic invertebrates
Authors: Blanckaert K. , Garcia X.‐F. , Ricardo A.‐M. , Chen Q. , Pusch M. T. 
Published: August 2012

ABSTRACTThe role of turbulence in the dislodgment of benthic stream invertebrates from the riverbed was investigated experimentally in a laboratory flume. For the first time, technological advances allowed measuring the spatio‐temporal patterns of turbulent flow around two free‐moving invertebrates (Aeshna cyanea and Somatochlora flavomaculata). A specific methodology was developed for the analysis of turbulence around benthic invertebrates. The results confirmed two hypotheses: (i) on the contrary to sediment particles, invertebrates are not only sensitive to the peak values of the turbulent flow forcing but also to the temporal fluctuations in this flow forcing; and (ii) the dominant temporal fluctuations are not due to local turbulent structures of the size of the invertebrate, but to turbulent structures that scale with the flow depth and are inherited from upstream. In 15 of the 17 conducted tests, important turbulent events that scale with the flow depth accompanied by rapid temporal flow fluctuations occurred at the moment of dislodgement. The dominant forcing was consistently a threefold increase in shear stress, and was related to a sweep event in 12 of the 17 tests. Thereby, the increase in longitudinal velocity was typically about 40%, which led to a 100% increase in drag force in comparison with the time‐averaged drag force. These results enable a new understanding of the detailed hydraulic conditions leading to passive drift of stream invertebrates. In addition, they open new perspectives to improve models predicting the distribution of benthic invertebrates based on hydrodynamics by accounting for turbulence. Copyright © 2012 John Wiley & Sons, Ltd.
Optimization of unsteady incompressible Navier–Stokes flows using variational level set method
Authors: Deng Yongbo , Zhang Ping , Liu Yongshun , Wu Yihui , Liu Zhenyu 
Published: August 2012

SUMMARYThis paper presents the optimization of unsteady Navier–Stokes flows using the variational level set method. The solid–liquid interface is expressed by the level set function implicitly, and the fluid velocity is constrained to be zero in the solid domain. An optimization problem, which is constrained by the Navier–Stokes equations and a fluid volume constraint, is analyzed by the Lagrangian multiplier based adjoint approach. The corresponding continuous adjoint equations and the shape sensitivity are derived. The level set function is evolved by solving the Hamilton–Jacobian equation with the upwind finite difference method. The optimization method can be used to design channels for flows with or without body forces. The numerical examples demonstrate the feasibility and robustness of this optimization method for unsteady Navier–Stokes flows.Copyright © 2012 John Wiley & Sons, Ltd.
Frequency of close positioning of chromosomal loci detected by FRET correlates with their participation in carcinogenic rearrangements in human cells
Authors: Gandhi Manoj , Evdokimova Viktoria , Nikiforov Yuri E. 
Published: August 2012

AbstractIt has been well established that genes participating in oncogenic rearrangements are non‐randomly positioned and frequently close to each other in human cell nuclei. However, the actual distance between these fusion partners has never been determined. The phenomenon of fluorescence resonance energy transfer (FRET) is observed when a donor fluorophore is close (<10 nm) to transfer some of it energy to an acceptor fluorophore. The aim of this study was to validate the use of FRET on directly labeled DNA molecules to assess the frequency of positioning at <10 nm distances between genes known to be involved in rearrangement and to correlate it with their probability to undergo rearrangement. In the validation experiments, the frequency of FRET‐sensitized emission (SE) was found to be 93–96% between probes for the immediately adjacent chromosomal regions as compared to 0.1–0.2% between probes for the random loci located on large linear separation. Further, we found that the frequency of FRET‐SE between four pairs of genes that form rearrangements in thyroid cancer was 5% forRETandCCDC6, 4% forRETandNCOA4, 2% forBRAFandAKAP9, and 2% forNTRK1andTPR. Moreover, the frequency with which FRET was observed showed strong correlation (r= 0.9871) with the prevalence of respective rearrangements in thyroid cancer. Our findings demonstrate that FRET can be used as a technique to analyze proximity between specific DNA regions and that the frequency of gene positioning at distances allowing FRET correlates with their probability to undergo chromosomal rearrangements. © 2012 Wiley Periodicals, Inc.
Lanthanide amides [(Me3Si)2N]3Ln(µ‐Cl)Li(THF)3‐catalyzed phospho‐aldol‐brook rearrangement reaction of dialkyl phosphites with isatins
Authors: Wang Lu , Yao Zhigang , Xu Fan , Shen Qi 
Published: August 2012

AbstractThe tetracoordinated lanthanide amides [(Me3Si)2N]3Ln(µ‐Cl)Li(THF)3 were found to serve as highly active catalysts for the phospho‐Aldol‐Brook rearrangement reaction of various dialkyl phosphites and isatins. The reactions produced dialkyl 2‐oxoindolin‐3‐yl phosphates in good to excellent yields in the presence of 1 mol% [(Me3Si)2N]3La(µ‐Cl)Li(THF)3 at room temperature within 5 min. A mechanism for this highly efficient process was proposed. © 2012 Wiley Periodicals, Inc. Heteroatom Chem 23:449–456, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21036
Palladium(II) complexes with aminomethylphosphine ligands as catalysts for the heck reaction
Authors: Keleş Mustafa , Yılmaz Mustafa Kemal 
Published: August 2012

AbstractNew, aminomethyldiphosphine (PCN) ligands, ((C6H5)2PCH2)2NR (R = C6H3 (CH3)(OH) (1a), C6H4OC6H5(1b), C6H4SC6H5) (1c)) and their Pd(II) complexes have been synthesized and characterized. These complexes were found to be efficient catalysts in the Heck reaction of activated and deactivated aryl halide with a variety of olefins. © 2012 Wiley Periodicals, Inc. Heteroatom Chem 23:466–471, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21038
Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo-controlled clinical trial
Authors: Squires Robert H. , Dhawan Anil , Alonso Estella , Narkewicz Michael R. , Shneider Benjamin L. , Rodriguez-Baez Norberto , Olio Dominic Dell , Karpen Saul , Bucuvalas John , Lobritto Steven , Rand Elizabeth , Rosenthal Philip , Horslen Simon , Ng Vicky , Subbarao Girish , Kerkar Nanda , Rudnick David , Lopez James M. , Schwarz Kathleen , Romero Rene , Elisofon Scott , Doo Edward , Robuck Patricia R. , Lawlor Sharon , Belle Steven H. 
Published: August 2012

Abstract

N-acetylcysteine (NAC) was found to improve transplantation-free survival in only those adults with nonacetaminophen (non-APAP) acute liver failure (ALF) and grade 1-2 hepatic encephalopathy (HE). Because non-APAP ALF differs significantly between children and adults, the Pediatric Acute Liver Failure (PALF) Study Group evaluated NAC in non-APAP PALF. Children from birth through age 17 years with non-APAP ALF enrolled in the PALF registry were eligible to enter an adaptively allocated, doubly masked, placebo-controlled trial using a continuous intravenous infusion of NAC (150 mg/kg/day in 5% dextrose in water [D5W]) or placebo (D5W) for up to 7 days. The primary outcome was 1-year survival. Secondary outcomes included liver transplantation-free survival, liver transplantation (LTx), length of intensive care unit (ICU) and hospital stays, organ system failure, and maximum HE score. A total of 184 participants were enrolled in the trial with 92 in each arm. The 1-year survival did not differ significantly (

P

= 0.19) between the NAC (73%) and placebo (82%) treatment groups. The 1-year LTx-free survival was significantly lower (

P

= 0.03) in those who received NAC (35%) than those who received placebo (53%), particularly, but not significantly so, among those less than 2 years old with HE grade 0-1 (NAC 25%; placebo 60%;

P

= 0.0493). There were no significant differences between treatment arms for hospital or ICU length of stay, organ systems failing, or highest recorded grade of HE.

Conclusion

: NAC did not improve 1-year survival in non-APAP PALF. One-year LTx-free survival was significantly lower with NAC, particularly among those <2 years old. These results do not support broad use of NAC in non-APAP PALF and emphasizes the importance of conducting controlled pediatric drug trials, regardless of results in adults.
Accumulated state assessment of the Peace-Athabasca-Slave River system
Authors: Dubé Monique G , Wilson Julie E 
Published: August 2012

Abstract
Effects-based analysis is a fundamental component of watershed cumulative effects assessment. This study conducted an effects-based analysis for the Peace-Athabasca-Slave River System, part of the massive Mackenzie River Basin, encompassing 20% of Canada's total land mass and influenced by cumulative contributions of the W.A.C. Bennett Dam (Peace River) and industrial activities including oil sands mining (Athabasca River). This study assessed seasonal changes in 1) Peace River water quality and quantity before and after dam development, 2) Athabasca River water quality and quantity before and after oil sands developments, 3) tributary inputs from the Peace and Athabasca Rivers to the Slave River, and 4) upstream to downstream differences in water quality in the Slave River. In addition, seasonal benchmarks were calculated for each river based on pre-perturbation post-perturbation data for future cumulative effects assessments. Winter discharge (January–March) from the Peace and Slave Rivers was significantly higher than before dam construction (pre-1967) (p &lt; 0.05), whereas summer peak flows (May–July) were significantly lower than before the dam showing that regulation has significantly altered seasonal flow regimes. During spring freshet and summer high flows, the Peace River strongly influenced the quality of the Slave River, as there were no significant differences in loadings of dissolved N, total P (TP), total organic C (TOC), total As, total Mn, total V, and turbidity and specific conductance between these rivers. In the Athabasca River, TP and specific conductance concentrations increased significantly since before oil sands developments (1967–2010), whereas dissolved N and sulfate have increased after the oil sands developments (1977–2010). Recently, the Athabasca River had significantly higher concentrations of dissolved N, TP, TOC, dissolved sulfate, specific conductance, and total Mn than either the Slave or the Peace Rivers during the winter months. The transboundary nature of the Peace, Athabasca, and Slave River basins has resulted in fragmented monitoring and reporting of the state of these rivers, and a more consistent monitoring framework is recommended.
Integr Environ Assess Manag 2013;9:405–425. © 2012 SETAC
Can natural variability trigger effects on fish and fish habitat as defined in Environment Canada's metal mining environmental effects monitoring program?
Authors: Mackey Robin , Rees Cassandra , Wells Kelly , Pham Samantha , England Kent 
Published: August 2012

Abstract
The Metal Mining Effluent Regulations (MMER) took effect in 2002 and require most metal mining operations in Canada to complete environmental effects monitoring (EEM) programs. An “effect” under the MMER EEM program is considered any positive or negative statistically significant difference in fish population, fish usability, or benthic invertebrate community EEM-defined endpoints. Two consecutive studies with the same statistically significant differences trigger more intensive monitoring, including the characterization of extent and magnitude and investigation of cause. Standard EEM study designs do not require multiple reference areas or preexposure sampling, thus results and conclusions about mine effects are highly contingent on the selection of a near perfect reference area and are at risk of falsely labeling natural variation as mine related “effects.” A case study was completed to characterize the natural variability in EEM-defined endpoints during preexposure or baseline conditions. This involved completing a typical EEM study in future reference and exposure lakes surrounding a proposed uranium (U) mine in northern Saskatchewan, Canada. Moon Lake was sampled as the future exposure area as it is currently proposed to receive effluent from the U mine. Two reference areas were used: Slush Lake for both the fish population and benthic invertebrate community surveys and Lake C as a second reference area for the benthic invertebrate community survey. Moon Lake, Slush Lake, and Lake C are located in the same drainage basin in close proximity to one another. All 3 lakes contained similar water quality, fish communities, aquatic habitat, and a sediment composition largely comprised of fine-textured particles. The fish population survey consisted of a nonlethal northern pike (Esox lucius) and a lethal yellow perch (Perca flavescens) survey. A comparison of the 5 benthic invertebrate community effect endpoints, 4 nonlethal northern pike population effect endpoints, and 10 lethal yellow perch effect endpoints resulted in the observation of several statistically significant differences at the future exposure area relative to the reference area and/or areas. When the data from 2 reference areas assessed for the benthic invertebrate community survey were pooled, no significant differences in effect endpoints were observed. These results demonstrate weaknesses in the definition of an “effect” used by the MMER EEM program and in the use of a single reference area. Determination of the ecological significance of statistical differences identified as part of EEM programs conducted during the operational period should consider preexisting (background) natural variability between reference and exposure areas. Integr Environ Assess Manag 2013; 9: 155–163. © 2012 SETAC
Differential entropy in wavelet sub‐band for assessment of glaucoma
Authors: Nath Malaya Kumar , Dandapat Samarendra 
Published: August 2012

AbstractGlaucoma is an eye disease that causes progressive optic neuropathy and vision loss due to degeneration of the optic nerves. Cup to disc ratio (CDR) is the standard measure for evaluation of glaucoma. It is difficult to estimate the value of CDR if the boundaries of cup and disc are not well defined. In this work, we propose a novel method based on differential entropy (DE) for evaluation of glaucoma. DE can be used as a measure of glaucoma as it is proportional to the probability of number of glaucoma pixels in wavelet sub‐bands. It has been shown that DE or negentropy value of 0.25 as an optimum threshold for glaucoma detection. This method is evaluated and its performance is compared with three existing methods using 54 retinal images. The proposed method shows the best result with an accuracy value of 92.59%. © 2012 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 22, 161–165, 2012