bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum Levels of Cytokines in Subjects With Generalized Chronic and Aggressive Periodontitis Before and After Non‐Surgical Periodontal Therapy: A Pilot Study
Authors: Duarte Poliana Mendes , da Rocha Marcelo , Sampaio Eduardo , Mestnik Maria Josefa , Feres Magda , Figueiredo Luciene Cristina , Bastos Marta Ferreira , Faveri Marcelo 
Published: March 2010

Background: The emergence of periodontal medicine has increased interest in defining the serologic profiles of inflammatory mediators in subjects with periodontitis. Thus, the aim of this pilot study is to evaluate the serum levels of tumor necrosis factor‐alpha (TNF‐α), interferon‐γ, and interleukin (IL)‐4, ‐17, and ‐23 in subjects with generalized chronic periodontitis (GCP) and generalized aggressive periodontitis (GAgP) before and after non‐surgical periodontal therapy.Methods: Cytokines were measured by enzyme‐linked immunosorbent assay in serum samples taken from 42 systemically healthy subjects divided according to periodontal status into subjects with GAgP (n = 14) and GCP (n = 14) and periodontally healthy (PH) subjects (n = 14). In addition, the levels of cytokines were reassessed at 6 months after periodontal therapy in the periodontitis groups. Clinical parameters were also evaluated at baseline and 6 months post‐therapy.Results: After therapy, both periodontitis groups demonstrated a significant improvement in clinical periodontal status (P <0.05). At baseline, concentrations of TNF‐α (P = 0.0006) and IL‐17 (P = 0.02) were significantly higher in the GAgP group compared to the other groups. There was a significant decrease in serum concentrations of TNF‐α (P = 0.03) and IL‐17 (P = 0.04) at 6 months post‐therapy in the GAgP group (P <0.05). The concentration of TNF‐α remained elevated in the GAgP group compared to the PH group at 6 months post‐therapy (P = 0.04).Conclusions: Subjects with GAgP presented higher levels of TNF‐α and IL‐17 than subjects with GCP and PH subjects. In addition, although the serum levels of these cytokines improved significantly as a result of periodontal therapy, the levels of TNF‐α remained higher in subjects with GAgP compared to PH subjects.
Realignment and Extended Fusion with Use of a Medial Column Screw for Midfoot Deformities Secondary to Diabetic Neuropathy
Authors: Assal Mathieu , Ray Adrien , Stern Richard 
Published: March 2010

BACKGROUND:
The failure of nonsurgical treatment of patients with midfoot and hindfoot deformity secondary to diabetic Charcot arthropathy may lead to a rocker-bottom foot deformity with recurrent or persistent plantar ulceration. We report our experience with realignment and extended fusion with primary use of a medial column screw for this midfoot deformity.

METHODS:
From July 2001 through July 2005, we performed reconstructive surgery on fifteen adults with diabetes mellitus who had a severe neuropathic midfoot deformity consisting of a collapsed plantar arch with a rocker-bottom foot deformity. Thirteen had a nonhealing midfoot plantar ulcer. All underwent realignment and arthrodesis with a medial column screw; some required additional fixation techniques depending on the extent of the deformity. Outcome measures included ulcer and surgical wound-healing, radiographic results, complications, and the need for amputation.

RESULTS:
The mean duration of clinical follow-up was forty-two months. Fourteen patients were able to walk, and there were no recurrent plantar ulcers. Thirteen patients were able to wear custom-made extra-depth, wide-toed shoes with molded inserts. One patient without prior ulceration had development of a deep infection that necessitated an amputation. Four feet had a nonunion, one of which was symptomatic requiring a revision to obtain union.

CONCLUSIONS:
Surgical reconstruction of a collapsed neuropathic foot deformity is technically demanding, but a successful outcome can result in a plantigrade foot that is free of ulceration and abnormal pressure points and a patient who is able to walk. The procedure described has an acceptable degree of complications although it has a high rate of nonunion.

LEVEL OF EVIDENCE:
Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.

ORIGINAL ABSTRACT CITATION:
“Realignment and Extended Fusion with Use of a Medial Column Screw for Midfoot Deformities Secondary to Diabetic Neuropathy” (2009;91:812-20).
Comparison of Arthroscopic and Open Treatment of Septic Arthritis of the Wrist
Authors: Sammer Douglas M. , Shin Alexander Y. 
Published: March 2010

BACKGROUND:
Open irrigation and débridement is the standard of treatment for septic arthritis of the wrist. Although isolated cases of arthroscopic irrigation and débridement have been reported, a comparison of arthroscopic and open techniques has not been performed, to our knowledge. The purpose of this study was to compare the two methods of management.

METHODS:
A retrospective comparison of patients with septic arthritis of the wrist initially treated, over an eleven-year period, with open or arthroscopic irrigation and débridement was undertaken at a single institution. The clinical presentation, laboratory and microbiological findings, hospital course, complications, and outcomes were compared between the two groups.

RESULTS:
Between 1997 and 2007, thirty-six patients with septic arthritis involving a total of forty wrists were identified. Nineteen wrists (seventeen patients) were initially treated with open irrigation and débridement, and twenty-one wrists (nineteen patients) were initially treated arthroscopically. Eleven wrists in the open-treatment cohort required repeat irrigation and débridement, and eight wrists in the arthroscopy cohort required a repeat procedure. If a repeat irrigation and débridement was required, it was performed in an open fashion in all but two cases. When the comparison included all of the patients in the series, no difference between the two cohorts was found with regard to the number of irrigation and débridement procedures required or the length of the hospital stay. However, when the comparison was limited to the patients with isolated septic arthritis of the wrist, it was found that only one of seven wrists in the open-treatment cohort but all eight wrists in the arthroscopy cohort had been successfully managed with a single irrigation and débridement procedure (p = 0.001). No patient in whom isolated septic arthritis of the wrist had been treated with arthroscopic irrigation and débridement required a second operation. The patients in whom isolated septic arthritis of the wrist was treated with the open method stayed in the hospital for an average of sixteen days compared with a six-day stay for those in whom isolated septic arthritis of the wrist was treated with the arthroscopic method (p = 0.04). The ninety-day perioperative mortality rate in the series was substantial (18% [three patients] in the open-treatment cohort and 21% [four patients] in the arthroscopy cohort).

CONCLUSIONS:
Arthroscopic irrigation and débridement is an effective treatment for patients with isolated septic arthritis of the wrist; these patients had fewer operations and a shorter hospital stay than did patients who had received open treatment. However, these benefits were not seen in patients with multiple sites of infection.

LEVEL OF EVIDENCE:
Therapeutic Level III. See Instructions to Authors for a complete description of levels of evidence.

ORIGINAL ABSTRACT CITATION:
“Comparison of Arthroscopic and Open Treatment of Septic Arthritis of the Wrist” (2009;91:1387-93).
Open Reduction and Internal Fixation of Proximal Humeral Fractures with Use of the Locking Proximal Humerus Plate
Authors: Konrad G. , Bayer J. , Hepp P. , Voigt C. , Oestern H. , Kääb M. , Luo C. , Plecko M. , Wendt K. , Köstler W. , Südkamp N. 
Published: March 2010

BACKGROUND:
The treatment of unstable displaced proximal humeral fractures, especially in the elderly, remains controversial. The objective of the present prospective, multicenter, observational study was to evaluate the functional outcome and the complication rate after open reduction and internal fixation of proximal humeral fractures with use of a locking proximal humeral plate.

METHODS:
One hundred and eighty-seven patients (mean age, 62.9 ± 15.7 years) with an acute proximal humeral fracture were managed with open reduction and internal fixation with a locking proximal humeral plate. At the three-month, six-month, and one-year follow-up examinations, 165 (88%), 158 (84%), and 155 (83%) of the 187 patients were assessed with regard to pain, shoulder mobility, and strength. The Constant score was determined at each interval, and the Disabilities of the Arm, Shoulder and Hand (DASH) score was determined for the injured and contralateral extremities at the time of the one-year follow-up.

RESULTS:
Between three months and one year, the mean range of motion and the mean Constant score for the injured shoulders improved substantially. Twelve months after surgery, the mean Constant score for the injured side was 70.6 ± 13.7 points, corresponding to 85.1% ± 14.0% of the score for the contralateral side. The mean DASH score at the time of the one-year follow-up was 15.2 ± 16.8 points. Sixty-two complications were encountered in fifty-two (34%) of 155 patients at the time of the one-year follow-up. Twenty-five complications (40%) were related to incorrect surgical technique and were present at the end of the operative procedure. The most common complication, noted in twenty-one (14%) of 155 patients, was intraoperative screw perforation of the humeral head. Twenty-nine patients (19%) had an unplanned second operation within twelve months after the fracture.

CONCLUSIONS:
Surgical treatment of displaced proximal humeral fractures with use of the locking proximal humeral plate that was evaluated in the present study can lead to a good functional outcome provided that the correct surgical technique is used. Because many of the complications were related to incorrect surgical technique, it behooves the treating surgeon to perform the operation correctly to avoid iatrogenic errors.

LEVEL OF EVIDENCE:
Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.

ORIGINAL ABSTRACT CITATION:
“Open Reduction and Internal Fixation of Proximal Humeral Fractures with Use of the Locking Proximal Humerus Plate. Results of a Prospective, Multicenter, Observational Study” (2009;91:1320-8).
Relationship between the Atlantic Multidecadal Oscillation index and variability of mean annual flows for catchments in the St. Lawrence watershed (Quebec, Canada) during the past century
Authors: Assani Ali A. , Landais David , Mesfioui Mhamed , Matteau Martin 
Published: March 2010

This paper, based on an analysis of the mean annual flow (MAF) of 16 natural rivers over the period 1934–2000, has the following goals: (1) to determine the different temporal variability modes of the MAF in the St. Lawrence watershed, (2) to describe the temporal variability of the streamflow in each mode and (3) to analyze the influence of the AMO (Atlantic Multidecadal Oscillation) on the interannual and interdecadal variability of mean annual flows in this Quebec watershed.
This paper shows that the interannual variability of mean annual flow was not synchronous on both sides of the river. During the period analyzed, MAF variability was characterized by a tendency to decrease on the south shore (right bank) but to increase on the north shore (left bank). A correlation analysis reveals that the influence of the AMO was limited exclusively to the north shore of the river, which is characterized by a continental climate. This correlation is negative. On the south shore, streamflow is correlated negatively to the AO (Arctic Oscillation).
Postmortem evaluation of surgery site leakage by use of in situ isolated pulsatile perfusion after partial liver lobectomy in dogs
Authors: Risselada Marije , Polyak Maximilian M. R. , Ellison Gary W. , Bacon Nicholas J. , Van Gilder James M. , Coomer Alastair R. , Thieman Kelley E. 
Published: March 2010

Abstract
Objective—To evaluate postmortem surgery site leakage by use of in situ isolated pulsatile perfusion after partial liver lobectomies.
Animals—10 healthy mixed-breed male dogs.
Procedures—Dogs were anesthetized, and 5 surgical techniques (pretied suture loop, energy-based sealer-divider, harmonic scalpel, suction with clip application, or suction with use of a thoracoabdominal stapler) were used to perform 5 partial liver lobectomies in each dog. Dogs were euthanatized, and the portal vein and hepatic artery were cannulated and perfused with a modified kidney perfusion machine (pulsatile flow for arterial perfusion and nonpulsatile flow for portal perfusion). Lobectomy sites were inspected for leakage of perfusate, and time until detection of leakage was recorded. The techniques in each dog were ranked on the basis of time until leakage. Time until leakage and rankings for each surgical technique were analyzed by use of an ANOVA.
Results—Leakage of perfusate was recorded in 44 lobes at supraphysiologic pressures. Of the 6 lobes without leakage, a pretied suture loop procedure was performed in 5 and a harmonic scalpel procedure was performed in 1. Time until leakage and the ranking differed significantly between the pretied suture loop and the other techniques. Time until leakage and ranking did not differ significantly among the other techniques.
Conclusions and Clinical Relevance—Time until leakage of perfusate was greater for the pretied suture loop technique than for the other techniques, and that technique did not fail in 5 of 10 lobes. However, all techniques appeared to be safe for clinical use.
Effects of aspirin, carprofen, deracoxib, and meloxicam on platelet function and systemic prostaglandin concentrations in healthy dogs
Authors: Blois Shauna L. , Allen Dana G. , Wood R. Darren , Conlon Peter D. 
Published: March 2010

Abstract
Objective—To determine effects of therapeutic dosages of aspirin, carprofen, deracoxib, and meloxicam on platelet function and systemic prostaglandin concentrations in healthy dogs.
Animals—10 hound-crossbred dogs.
Procedures—Aspirin (10 mg/kg, PO, q 12 h), carprofen (4.4 mg/kg, PO, q 24 h), deracoxib (2 mg/kg, PO, q 24 h), meloxicam (0.1 mg/kg, PO, q 24 h), and a placebo were administered for 7 days in a random order to each of 10 healthy dogs; there was a 21-day washout period between subsequent treatments. One-stage prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen concentration, and plasma concentrations of thromboxane (TX)B2 and 6-keto prostaglandin (PG)F1α were measured before and after treatment administration. Platelet function was assessed by use of a platelet-function analyzer and aggregation.
Results—Aspirin, carprofen, and meloxicam did not significantly affect platelet function. Deracoxib caused a mild decrease in platelet aggregation induced by 50μM ADP. Platelet number, Hct, PT, aPTT, and plasma TXB2 and 6-keto PGF1α concentrations were unchanged after NSAID administration. Meloxicam administration resulted in a significant decrease in fibrinogen concentration, but results remained within the laboratory reference interval.
Conclusions and Clinical Relevance—Oral administration of commonly used NSAIDs at therapeutic dosages in healthy dogs did not alter plasma TXB2 and 6-keto PGF1α concentrations. Deracoxib administration resulted in a minor abnormality in platelet aggregation. Anti-inflammatory doses of aspirin did not affect platelet function as measured by use of optical aggregometry and a platelet-function analyzer. Further evaluation of the effects of aspirin and cyclooxygenase-2–selective inhibitors on hemostasis should be performed.
Comparison of strength of the human-animal bond between Hispanic and non-Hispanic owners of pet dogs and cats
Authors: Schoenfeld-Tacher Regina , Kogan Lori R. , Wright Mary L. 
Published: March 2010

Abstract
Objective—To assess differences in strength of the human-animal bond between Hispanic and non-Hispanic owners and determine whether these variations were associated with differences in medical care for pets.
Design—Survey.
Sample Population—419 pet owners presenting a dog or cat for veterinary services at private veterinary clinics in Aurora, Colo; Chula Vista, Calif; and Mexico City.
Procedures—Owner and pet demographic information was obtained via open-ended interview questions. The human-animal bond was assessed through the Lexington Attachment to Pets Scale. Pet health data were obtained from medical records for the specific visit observed, and a body condition score was assigned.
Results—Hispanics were more likely to own sexually intact dogs and cats as pets than were individuals of other race-ethnicity groups. Overall, owners were most likely to classify their pets as providing companionship. When data for the 2 US locations were examined separately, no significant difference existed between how non-Hispanic White and Hispanic owners viewed their pets, and scores for the Lexington Attachment to Pets Scale did not differ significantly among race-ethnicity groups.
Conclusions and Clinical Relevance—There was a strong human-animal bond among Hispanic respondents, and Hispanic pet owners in the United States and Mexico verbalized this attachment in similar ways to non-Hispanic White owners. There was no observed association between owner race-ethnicity and strength of the human-animal bond for Hispanic and non-Hispanic White pet owners in the United States. Thus, other factors must be considered to explain the observed difference in percentages of neutered animals between groups.
Ovarian remnant syndrome in dogs and cats: 21 cases (2000–2007)
Authors: Ball Rebecca L. , Birchard Stephen J. , May Lauren R. , Threlfall Walter R. , Young Gregory S. 
Published: March 2010

Abstract
Objective—To describe signalment, clinical findings, diagnostic tests, and results of treatment of dogs and cats with ovarian remnant syndrome (ORS).
Design—Retrospective case series.
Animals—19 dogs and 2 cats with ORS.
Procedures—Medical records for animals examined between June 2000 and October 2007 were reviewed for signalment, clinical signs, age at time of ovariohysterectomy (OHE), surgical findings during OHE, experience of the surgeon (veterinary student vs veterinarian), interval from OHE until diagnosis of ORS, results of diagnostic tests, surgical findings, and results of histologic examination of excised tissues.
Results—21 animals (19 dogs and 2 cats) with ORS were identified. The most common clinical signs were those associated with proestrus and estrus. More dogs than cats were affected, and all residual ovarian tissues were found in the region of the ovarian pedicles. The right ovary in dogs was affected significantly more often than the left ovary. Seven animals had neoplasms of the reproductive system. These animals had a significantly longer interval between OHE and diagnosis of ORS than did the 14 animals without neoplasms. Long-term follow-up of 18 animals revealed resolution of clinical signs following exploratory laparotomy.
Conclusions and Clinical Relevance—Ovarian remnants were found in typical locations for ovaries and were not considered ectopic tissue; thus, surgical error during OHE was suspected as the cause of ORS. Anatomic differences may account for differences between species, and clinical signs may not be recognized until years after OHE. Surgical removal of residual ovarian tissue resulted in resolution of clinical signs.
Successful treatment of a Vietnamese potbellied pig with an ovarian leiomyoma
Authors: Baumwart Chad A. , Prado Tulio M. , Anderson Megan P. , Coffman Elizabeth A. , Simpson Katie M. , Campbell Gregory A. 
Published: March 2010

Abstract
Case Description—An adult sexually intact female Vietnamese potbellied pig was examined because of abdominal distention of 5 months' duration.
Clinical Findings—The pig was moderately anemic, and its abdomen was greatly distended. A freely movable abdominal mass was detected during palpation and ultrasonographic examination of the abdomen. Examination of abdominal and thoracic radiographs revealed faint, ill-defined, linear and curvilinear mineralized opacities in the region of the mass and that the gastrointestinal tract was displaced craniodorsally. Results of radiographic exami-nation suggested that the cause of distention was a single abdominal mass (possibly a neoplasm).
Treatment and Outcome—Surgery was performed, and the mass, which was identified as the right ovary, was removed. The left ovary had a normal appearance, but it was also removed during surgery. The pig was administered a transfusion (314 mL of plasma and 296 mL of packed RBCs) before and during surgery. The mass, which accounted for ap-proximately one-third of the pig's body weight, was identified histologically as an ovarian leiomyoma.
Clinical Relevance—Pigs can safely be administered a transfusion of RBCs and plasma. Ovarian tumors can be removed from Vietnamese potbellied pigs, which allows them to be used as pets or for reproduction when only 1 ovary is affected. Uterine masses in older sexually intact Vietnamese potbellied pigs are more common than are ovarian tumors; thus, complete ovariohysterectomy should be considered when the primary purpose of the pig is to serve as a pet.
Production and Characterization of PP/LDPE Blend Filament Yarns under Industrial Conditions
Authors: Mehrabli B. , Shoushtari A. M. , Mojtahedi M. R. M. 
Published: March 2010

Abstract
Manufacturing of blend man-made fibers especially from polyolefins due to their new and expanded applications has attracted the researchers and technologists' attention. In this study, PP/LDPE blend filament yarn samples with various ratios of 100/0, 99/1, 97/3, 95/5, 93/7, 90/10 were melt spun and then drawn under industrial conditions. According to the results of the melt spinning process, convenient spinnability comparing to pure PP for various polyblend samples up to 10 wt.% of LDPE was observed. Results of microstructure measurements in both group i.e. as-spun and drawn samples showed that the presence of LDPE in blend samples did not deteriorate the density and crystallinity of PP. However, increasing the fraction of LDPE in blend gave rise to noticeable increase in the shrinkage values of drawn samples in comparing to pure PP. Although the tenacity of as-spun and drawn yarns displayed a downward trend by increasing the LDPE in blend, the obtained values for tenacity are still at an acceptable level for further processing or textile applications.