bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing Injection Molding Optimization for SFRPs Through Multi‐Fidelity Data‐Driven Approaches Incorporating Prior Information in Limited Data Environments
Authors: Lee Hugon , Lee Mingyu , Jung Jiyoung , Lee Ikjin , Ryu Seunghwa 
Published: May 2024

AbstractInjection molding is one of the dominant methods for mass‐producing short fiber reinforced plastics renowned for their exceptional specific properties. In the utilization of such composite components, optimization of process parameters significantly influences material characteristics and part performance. However, in industrial practice, this process often relies on intuition and iterative experimentation. Prior studies have introduced data‐efficient optimization methods but faced limitations in adopting minor variations in the product development cycle. This study introduces a multi‐fidelity optimization framework aimed at efficiently addressing new problems by leveraging previously acquired knowledge from analogous domains, particularly accommodating alterations in material scenarios. Two data‐driven frameworks are explored: 1) Gaussian process‐based and 2) neural network‐based, each employing distinct information‐transferring techniques, hierarchical Kriging and transfer learning, respectively. Bayesian optimization of process parameters under limited data budget, which is typical in realistic industrial settings, is performed. The results highlight the efficiency of the proposed framework, demonstrating superior performance not only in data‐driven modeling but also in optimization efficiency compared to conventional single‐fidelity approaches. The Pearson correlation coefficient is utilized to assess the applicability of the multi‐fidelity framework in handling the inherent ambiguity of the similarity of problem scenarios. The proposed method is believed to be adaptable and versatile, offering potential application across various challenges in process optimization.
Synergetic Triple Absorber Based High‐Efficiency Solar Cell Design
Authors: Gopila M , Prabu R. Thandaiah , Kumar ATA Kishore , Kumar Atul 
Published: May 2024

AbstractComputational analysis of triple absorber‐based solar cell structure is undertaken. This solar cell device configuration allows better utilization of the incident solar spectrum. Three different absorbers with a band gap in the range 1–1.5 eV are sandwiched between high‐doped p+ and n+ regions in descending order of electron affinity to form an energy‐matched multiple absorber device. A comprehensive analysis of key device parameters influencing performance, including band gap, conduction band alignment, interfacial defects, and thickness, is presented. The optimized triple absorber device shows beyond Shockley–Queisser limit (SQ limit) performance under the constraint of passivated interfaces with defect density below 1013 cm−2. Wide spectrum coverage leads to high short circuit current and an efficiency of 40.3%, which is higher than the SQ limit for single band gap solar cell.
The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
Authors: Leung Yuet‐Kin , Lee Sung‐Gwon , Wang Jiang , Guruvaiah Ponmari , Rusch Nancy J , Ho Shuk‐Mei , Park Chungoo , Kim Kyounghyun 
Published: May 2024

AbstractThe orphan nuclear receptor NR2E3 (Nuclear receptor subfamily 2 group E, Member 3) is an epigenetic player that modulates chromatin accessibility to activate p53 during liver injury. Nonetheless, a precise tumor suppressive and epigenetic role of NR2E3 in hepatocellular carcinoma (HCC) development remains unclear. HCC patients expressing low NR2E3 exhibit unfavorable clinical outcomes, aligning with heightened activation of the Wnt/β‐catenin signaling pathway. The murine HCC models utilizing NR2E3 knockout mice consistently exhibits accelerated liver tumor formation accompanied by enhanced activation of Wnt/β‐catenin signaling pathway and inactivation of p53 signaling. At cellular level, the loss of NR2E3 increases the acquisition of aggressive cancer cell phenotype and tumorigenicity and upregulates key genes in the WNT/β‐catenin pathway with increased chromatin accessibility. This event is mediated through increased formation of active transcription complex involving Sp1, β‐catenin, and p300, a histone acetyltransferase, on the promoters of target genes. These findings demonstrate that the loss of NR2E3 activates Wnt/β‐catenin signaling at cellular and organism levels and this dysregulation is associated with aggressive HCC development and poor clinical outcomes. In summary, NR2E3 is a novel tumor suppressor with a significant prognostic value, maintaining epigenetic homeostasis to suppress the Wnt/β‐catenin signaling pathway that promotes HCC development.
Region‐Specific CD16+ Neutrophils Promote Colorectal Cancer Progression by Inhibiting Natural Killer Cells
Authors: Zhang Yan , Wang Zien , Lu Yu , Sanchez David J. , Li Jiaojiao , Wang Linghao , Meng Xiaoxue , Chen Jianjun , Kien Tran Trung , Zhong Ming , Gao Wei‐Qiang , Ding Xianting 
Published: May 2024

AbstractThe colon is the largest compartment of the immune system, with innate immune cells exposed to antigens in the environment. However, the mechanisms by which the innate immune system is instigated are poorly defined in colorectal cancer (CRC). Here, a population of CD16+ neutrophils that specifically accumulate in CRC tumor tissues by imaging mass cytometry (IMC), immune fluorescence, and flow cytometry, which demonstrated pro‐tumor activity by disturbing natural killer (NK) cells are identified. It is found that these CD16+ neutrophils possess abnormal cholesterol accumulation due to activation of the CD16/TAK1/NF‐κB axis, which upregulates scavenger receptors for cholesterol intake including CD36 and LRP1. Consequently, these region‐specific CD16+ neutrophils not only competitively inhibit cholesterol intake of NK cells, which interrupts NK lipid raft formation and blocks their antitumor signaling but also release neutrophil extracellular traps (NETs) to induce the death of NK cells. Furthermore, CD16‐knockout reverses the pro‐tumor activity of neutrophils and restored NK cell cytotoxicity. Collectively, the findings suggest that CRC region‐specific CD16+ neutrophils can be a diagnostic marker and potential therapeutic target for CRC.
Steep Slope Field Effect Transistors Based on 2D Materials
Authors: Qin Laixiang , Tian He , Li Chunlai , Xie Ziang , Wei Yiqun , Li Yi , He Jin , Yue Yutao , Ren Tian‐Ling 
Published: May 2024

AbstractWith field effect transistor (FET) sustained to downscale to sub‐10 nm nodes, performance degradation originates from short channel effects (SCEs) degradation and power consumption increment attributed to inhibition of supply voltage (VDD) scaling down proportionally caused by thermionic limit subthreshold swing (SS) (60 mV dec−1) pose substantial challenges for today's semiconductor industry. To further sustain the Moore's law life, incorporation of new device concepts or new materials are imperative. 2D materials are predicted to be able to combat SCEs by virtue of high carrier mobility maintainability regardless of thickness thinning down, dangling bonds free surface and atomic thickness, which contributes to super gate electrostatic controllability. To overcome increasing power dissipation problem, new device structures including negative capacitance FET (NCFET), tunnel FET (TFET), dirac source FET (DSFET) and the like, which show superiority in decreasing VDD by lowering SS below thermionic limit of 60 mV dec−1have been brought out. The combination of 2D materials and ultralow steep slope device structures holds great promise for low power‐dissipation electronics, which encompass both suppressed SCEs and reduced VDD simultaneously, leading to improved device performance and lowered power dissipation.
High‐Energy Nitrogen Rings Stabilized by Superatomic Properties
Authors: Gong Zhen , Wang Rui , Yu Famin , Wan Chenxi , Yang Xinrui , Wang Zhigang 
Published: May 2024

AbstractHow to stabilize nitrogen‐rich high‐energy‐density molecules under conventional conditions is particularly important for the energy storage and conversion of such systems and has attracted extensive attention. In this work, the theoretical study shows for the first time that the stabilization mechanism of the nitrogen ring conforms to the superatomic properties at the atomic level. This result occurs because the stabilized anionic nitrogen rings generally exhibit planar high symmetry and the injected electrons occupy the superatomic molecular orbitals (SAMOs) of the nitrogen rings. According to these results, the typical stabilized anionic nitrogen ring structures N64−, N5−, and N42− are identified, which possess delocalized molecular orbitals with the same symmetry as the atomic orbitals and electron arrangement consistent with the electron shell arrangement of the atom. On this basis, a pathway is further designed to stabilize nitrogen rings by introducing metal atoms as electron donors to form neutral ThN6, LiN5, and MgN4 structures, thereby replacing the anionization of systems. This study highlights the importance of developing nitrogen‐rich energetic materials from the perspective of superatoms.
Ru2P/Ir2P Heterostructure Promotes Hydrogen Spillover for Efficient Alkaline Hydrogen Evolution Reaction
Authors: Hong Yongju , Jeong Sangyeon , Seol Jae Hun , Kim Taekyung , Cho Seong Chan , Lee Tae Kyung , Yang Chaeyoen , Baik Hionsuck , Park Hyun S. , Lee Eunsoo , Yoo Sung Jong , Lee Sang Uck , Lee Kwangyeol 
Published: May 2024

AbstractEfficient and durable electrocatalysts toward alkaline hydrogen evolution reaction (HER) are of great significance for the widespread application of anion‐exchange membrane water electrolyzer (AEMWE). Numerous single‐phase catalysts, such as Ru2P, have been explored as efficient HER catalysts; however, many have failed to overcome the inherent sluggish kinetics of the two separate steps involved in the alkaline HER: water dissociation and hydrogen production. In this study, density functional theory calculations are conducted to identify promising combinations of Ir2P and Ru2P materials that promote fast cascade water dissociation and H2 production via kinetically favorable hydrogen spillover from the Ru2P surface to the adjacent Ir2P. An unprecedented construction of Ir2P cluster‐decorated Ru2P hollow nanotubes (c‐RP/IP HNTs), which feature a cooperative heterostructural synergy are developed. This configuration shows greater performance than commercial Pt/C, achieving an overpotential of 23.2 mV at 10 mA cm−2 and maintaining long‐term stability for 55 h in half‐cell tests. Furthermore, the practical AEMWE test, incorporating c‐RP/IP HNTs, demonstrated a remarkable single‐cell performance of 12.23 A cm−2 at 2.0 V and operated stably under 1.0 A cm−2 for over 250 h. This surpasses that of the state‐of‐the‐art proton‐exchange membrane WE.
A Highly Reversible Sn‐Air Battery Possessing the Ultra‐Low Charging Potential with the Assistance of Light
Authors: Gao Mingze , Wang Ruiya , Lu Xinxin , Fan Yanchen , Guo Ziyang , Wang Yonggang 
Published: May 2024

AbstractAqueous Sn‐air batteries are attracting a great deal of interest in recent years due to the ultra‐high safety, low cost, dendrite‐free and highly reversible Sn anode. However, the slurry oxygen reduction/evolution reaction (ORR/OER) kinetics on the air cathodes seriously affect the Sn‐air battery performances. Although various advanced catalysts have been developed, the charge overpotentials (~1000 mV) of these Sn‐air batteries are still not satisfactory. Herein, iron oxide (Fe2O3) modified titanium dioxide (TiO2) nanorods with heterogeneous structure are firstly synthesized on Ti mesh (Fe2O3@TiO2/Ti), and the obtained Fe2O3@TiO2/Ti films are further applied as catalytic electrodes for Sn‐air batteries. The core–shell heterogeneous structure of Fe2O3@TiO2/Ti can effectively facilitate the conversion of electrochemical intermediates and separation of photo‐excited electrons and holes to activate oxygen‐related reaction processes. Density functional theory (DFT) and experimental results also confirm that Fe2O3@TiO2/Ti can not only act as the electrocatalysts to improve ORR/OER properties, but also exhibit the superior photo‐catalytic activity to promote charging kinetics. Hence, the Fe2O3@TiO2/Ti‐based Sn‐air batteries show ultra‐low overpotential of ~40 mV, excellent rate capability and good cycling stability under light irradiation. This work will shed light on rational photo‐assisted catalytic cathode design for new‐type metal‐air batteries.
Two‐step preparation of phosphorus‐containing organoclay and its effect on fire‐resistant and mechanical properties of the flame‐retardant polyethylene composite
Authors: Thi Nhung Hac , Van Hoang Toan , Doanh Truong Cong , Oanh Ho Thi , Dat Doan Tien , Nguyen Ha Tran , Le‐Nhat‐Thuy Giang , Tran Quang Vinh , Hoang Mai Ha , Van Nguyen Tuyen 
Published: May 2024

AbstractIn this study, a nanohybrid based on montmorillonite (oMMT2) was prepared through a two‐step method using Arquad MCB‐80 and 9,10‐dihydro‐9‐oxa‐10‐phosphaphenanthrene‐10‐oxide (DOPO) as intercalation agents. The nanohybrid exhibited a basal spacing of 31.5 Å, which contained approximately 12.3% of Arquad MCB‐80 and 31.6% of DOPO. Various amount of oMMT2 nanohybrid was incorporated into a flame‐retardant polyethylene system containing aluminum trihydroxide and red phosphorus with a constant total additive content of 20 wt%. The dispersibility of oMMT2 in the composite matrix was evaluated by energy dispersive x‐ray mapping and x‐ray diffraction analyses. At a content of 3 wt% in the nanocomposite, oMMT2 showed a highly exfoliated state, while at a 5% content, a partially exfoliated and intercalated state was observed. A synergistic flame‐retardant effect between the nanohybrid and the mixture of aluminum trihydroxide and red phosphorus was found. The nanocomposite loading 3 wt% oMMT2 demonstrated the best flame retardancy, achieving a V‐0 rating of the vertical burning test with a limiting oxygen index of 27.6%. Moreover, the addition of the low oMMT2 contents (≤3 wt%) improved the mechanical properties of the flame‐retardant composite.
Reproducibility between preschool and school‐age Social Responsiveness Scale forms in the Environmental influences on Child Health Outcomes program
Authors: Patti Marisa A. , Croen Lisa A. , Dickerson Aisha S. , Joseph Robert M. , Ames Jennifer L. , Ladd‐Acosta Christine , Ozonoff Sally , Schmidt Rebecca J. , Volk Heather E. , Hipwell Alison E. , Magee Kelsey E. , Karagas Margaret , McEvoy Cindy , Landa Rebecca , Elliott Michael R. , Mitchell Daphne Koinis , D'Sa Viren , Deoni Sean , Pievsky Michelle , Wu Pei‐Chi , Barry Fatoumata , Stanford Joseph B. , Bilder Deborah A. , Trasande Leonardo , Bush Nicole R. , Lyall Kristen ,   program collaborators for Environmental Influences on Child Health Outcomes
Published: May 2024

AbstractEvidence suggests core autism trait consistency in older children, but development of these traits is variable in early childhood. The Social Responsiveness Scale (SRS) measures autism‐related traits and broader autism phenotype, with two age‐dependent forms in childhood (preschool, 2.5–4.5 years; school age, 4–18 years). Score consistency has been observed within forms, though reliability across forms has not been evaluated. Using data from the Environmental Influences on Child Health Outcomes (ECHO) program (n = 853), preschool, and school‐age SRS scores were collected via maternal report when children were an average of 3.0 and 5.8 years, respectively. We compared reproducibility of SRS total scores (T‐scores) and agreement above a clinically meaningful cutoff (T‐scores ≥ 60) and examined predictors of discordance in cutoff scores across forms. Participant scores across forms were similar (mean difference: 3.3 points; standard deviation: 7), though preschool scores were on average lower than school‐age scores. Most children (88%) were classified below the cutoff on both forms, and overall concordance was high (92%). However, discordance was higher in cohorts following younger siblings of autistic children (16%). Proportions of children with an autism diagnoses were also higher among those with discordant scores (27%) than among those with concordant scores (4%). Our findings indicate SRS scores are broadly reproducible across preschool and school‐age forms, particularly for capturing broader, nonclinical traits, but also suggest that greater variability of autism‐related traits in preschool‐age children may reduce reliability with later school‐age scores for those in the clinical range.
A review of the co‐liquefaction of biomass feedstocks and plastic wastes for biofuel production
Authors: Baloyi Hope , Patel Bilal 
Published: May 2024

AbstractInterest has emerged recently in addressing the long‐standing issue of waste plastic disposal and environmental challenges through the co‐liquefaction of waste plastics with eco‐friendly renewable biomass resources, including microalgae biomass and lignocellulosic biomass, to produce biofuels. Co‐liquefaction provides a viable alternative for managing plastic waste while contributing to biofuel production. The purpose of this article is to provide a comprehensive review of the advances in the co‐liquefaction of various mixtures of plastic waste and different types of biomass feedstocks (lignocellulosic and algal) for the production of biofuels.The influence of various reaction parameters, such as feedstock composition (blending ratio), temperature, catalyst type and loading, solvents, and reaction time on the product yield are explored. The synergistic interaction during the co‐liquefaction of biomass and plastic and the distribution and properties of biofuel products are also discussed.The findings demonstrate that maximum product yields vary depending on the final temperature, and the blending ratio plays a crucial role in determining the distribution of liquefaction products. Of particular interest is biocrude oil, the components of which are influenced by the composition of the feedstock material. The distribution of organic elements in the biochar is contingent upon the type of plastic used. Although the analysis of gas‐phase components is often overlooked, the reaction medium's composition is shown to impact the resulting gas composition.Finally, based on the insights gleaned from the literature, this review presents future perspectives on the subject matter. In general, the co‐liquefaction process offers a viable option for sustainable biofuel production and is a promising approach to address the waste plastics disposal challenges effectively, contributing to the valorization of plastic waste to achieve a circular bioeconomy in the future.
Stent dislodgement during withdrawal attempt into the guiding‐catheter: A step‐by‐step retrieval technique
Authors: Spînu Radu , Mangin Lionel , Pilichowski Hugo , Belle Loïc , Bonnet Marc 
Published: May 2024

AbstractCatheter‐induced stent dislodgement may occur when attempting to withdraw the stent into the guide‐catheter particularly in cases of guiding‐catheter co‐axiality issues. We present the management of a catheter‐induced stent dislodgement with simultaneous loss of wire position.
Multimodal imaging assessment for feasibility of endovascular reconstruction in cases of inferior vena cava atresia
Authors: Kisling Adam , Basile Sean , Dagher Adelle , Sexton Jonathan , Twerdahl Eric 
Published: May 2024

Key Clinical MessageInferior vena cava atresia is a rare condition with highly variable anatomy due to the complexity of caval embryology. When endovascular venovenous reconstruction is considered for severe persistent sequelae, multimodality imaging with CT and invasive venography is used to determine the appropriateness of intervention and for procedural planning.
Primary extraperitoneal hydatid cyst, a rare differential diagnosis of subdiaphragmatic mass: A case report
Authors: Ghandhari Maryam , Mehri Amirhossein , Doostparast Armin , Gharib Masoumeh , Rezaei Reza 
Published: May 2024

Key Clinical MessageHydatid cyst is a sly disease that can manifest with a spectrum of symptoms in almost every part of the human body, so it is crucial to be familiar with different scenarios that a patient may present.AbstractThe echinococcus granulosus parasite causes hydatid disease and is common in areas with animal husbandry and agriculture. Here, we report a middle age woman who presented with abdominal pain that further investigation revealed a cyst in subdiaphragmatic area.
Uncommon manifestation of Ebstein anomaly: A case report of apical displacement involving all tricuspid valve leaflets
Authors: Jalali Amirhossein , Khajali Zahra , Parsaee Mozhgan , Behrooj Soudabe , Salehi Pegah , Akbarian Mahsa , Shemshadi Sara , Hooshyar Dariush 
Published: May 2024

Key Clinical MessageThis case report presents an uncommon variant of Ebstein anomaly, where all three tricuspid valve leaflets exhibited apical displacement—a rare finding. It illustrates the complexities in diagnosing and managing such atypical presentations, with successful surgical correction through annuloplasty. The report adds valuable insights to the limited literature on this congenital heart disease.AbstractEbstein anomaly (EA), a rare congenital heart disorder, presents with diverse clinical spectrums. This case report explores a distinctive manifestation of EA, where all three tricuspid valve (TV) leaflets exhibited apical displacement, highlighting a novel aspect in the presentation of this condition. A 44‐year‐old woman, under long‐term medical surveillance for EA, showcased an atypical clinical trajectory marked by the apical displacement of all TV leaflets, which is uncommon in EA. Despite a predominantly asymptomatic course, recent exacerbation of symptoms prompted further evaluation. Diagnostic modalities, including echocardiography and cardiac magnetic resonance imaging, revealed severe tricuspid regurgitation concomitant with unprecedented apical displacement of the anterior, septal, and posterior tricuspid leaflets. The displacement of the anterior leaflet was contrary to typical embryonic valvular formation expectations, indicating a unique presentation within EA. The patient underwent annuloplasty surgery, which successfully rectified the anomalous TV architecture. Postoperative evaluation demonstrated mild residual tricuspid regurgitation, and the patient was discharged in stable condition. This case underscores the variability in EA presentations and accentuates the significance of tailored surgical interventions. The observation of apical displacement involving all TV leaflets adds a unique dimension to the existing EA literature, reinforcing the need for careful diagnosis and personalized treatment approaches.
Functional neurological disorder mimicking stroke: A case report
Authors: Venturini G. , Sarti C. 
Published: May 2024

KEY CLINICAL MESSAGEEven in the era of technology‐guided medicine, the clinician must integrate into his daily practice a careful anamnesis and physical examination to be conducted within a close doctor–patient relationship. All these elements, together with tools such as teleconsultation and digitalized medical records, are able to significantly increase the effectiveness of health care action.