bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of Association of Vitamin D Receptor Gene Polymorphisms with Diabetic Nephropathy
Authors: Esha Bhuiya , Yogaprabhu Saravanan , Sneha Janaki , Vijayalakshmi Karthick , Mohan Viswanathan , Radha Venkatesan , Bodhini Dhanasekaran 
Published: June 2024

Abstract

Background:
Type 2 diabetes leads to many microvascular complications, including diabetic nephropathy, also referred to as diabetic kidney disease. Vitamin D deficiency may play a role in the development of type 2 diabetes and nephropathy. The functions of vitamin D are mediated through vitamin D receptor (VDR). Three single nucleotide polymorphisms (SNPs) in VDR gene, namely, TaqI (rs731236), ApaI (rs7975232), and BsmI (rs1544410), have been widely studied in association with diabetes and nephropathy. The objective of this study was to investigate the association of these VDR gene SNPs with nephropathy in the South Indian population. Additionally, the effect of VDR gene variants on vitamin D levels was also investigated.

Subjects and Methods:
Two hundred forty-eight individuals with type 2 diabetes without nephropathy (T2DM) and 399 individuals with type 2 diabetes with nephropathy (T2DN) were genotyped for this study. Genotyping of TaqI was performed using the polymerase chain reaction-restriction fragment length polymorphism method. BsmI and ApaI were genotyped using MassArray. Anthropometric and biochemical data were collected for all participants. Vitamin D levels were measured in a subset of 47 T2DM and 74 T2DN individuals. Statistical analysis was performed using Statistical Package for the Social Sciences version 21.0 (IBM Corporation, Armonk, NY).

Results:
The genotype and minor allele frequencies of TaqI, BsmI, and ApaI were not significantly different between T2DM and T2DN groups. However, vitamin D levels were significantly reduced in T2DN (15.5 ± 1.16 ng/ml) compared to T2DM (20.5 ± 2.11 ng/ml, P = 0.027). No significant differences were found in the vitamin D levels when the T2DM and T2DN groups were stratified based on TaqI, BsmI, and ApaI genotypes.

Conclusion:
This study did not find a significant association of VDR SNPs (TaqI, BsmI, and ApaI) with T2DN. However, the study suggested a protective role of vitamin D levels in T2DN.
Neuromuscular Taping in Diabetes Mellitus: A Narrative Review of Current Understanding and Potential Therapeutic Applications
Authors: Sharma Abhishek , Sharma Nidhi , Chahal Aksh 
Published: June 2024

Abstract

Background:
Diabetes Mellitus (DM) poses significant challenges, including peripheral neuropathy and impaired muscle function. Neuromuscular taping has emerged as a noninvasive therapeutic approach, potentially offering benefits in managing DM-related complications.

Materials and Methods:
A comprehensive literature search was conducted to identify relevant studies investigating the use of neuromuscular taping in individuals with DM. Key databases were explored using Boolean operators (AND, OR, etc.), and articles were selected based on predefined inclusion criteria.

Results:
The review identifies 22 relevant articles, with 8 specifically addressing NMT in DM. Out of these, 5 were randomized controlled trials, highlighting the research interest in assessing the effectiveness of NMT. The findings suggest that NMT may positively impact the Ankle Brachial Index, indicative of improved peripheral blood circulation and many other health-related parameters. Neuromuscular taping principles and application methods are outlined, providing a foundation for understanding its potential therapeutic effects.

Discussion:
The potential therapeutic mechanisms of neuromuscular taping are explored, emphasizing its influence on sensory feedback, muscle activation, and circulation. Safety considerations and the feasibility of integrating neuromuscular taping into comprehensive DM management are discussed.

Conclusion:
Neuromuscular taping holds promise as an adjunctive therapy for managing DM-related complications. This structured narrative review provides a comprehensive overview for health care limitations such as a lack of standardized protocols and heterogeneity in study designs are noted.
Presentation and Outcome of Infection in Hospitalized Patients with Diabetic Foot at a Tertiary Care Hospital
Authors: Miyan Zahid , Waris Nazish , Zafar Awn Bin , Shafiq Uroosa , Ulhaque Muhammad Saif , Muneeb Muhammad Danish , Tahir Bilal , Basit Abdul 
Published: June 2024

Abstract

Background and Aim:
To observe presentation and outcome of diabetic foot infection (DFI) in hospitalized patients at a tertiary care center.

Materials and Methods:
This prospective clinical study included all those patients who visited the out-patient department (OPD) of the foot clinic of Baqai Institute of Diabetology and Endocrinology and were admitted to the hospital due to DFI from August 2020 to April 2021. Patients with DFI were assessed and classified into mild, moderate, and severe infections according to the Infectious Disease Society of America (IDSA)/International Working Group On Diabetic Foot guideline protocol. Primary outcome was healing either without amputation, or with minor or major amputation.

Results:
A total of 2405 patients visited the OPD and 658 got admitted. Of these 211 patients with DFI were included. Males 158 (75%) were predominant. As per IDSA classification, 99 (46.9%) had severe infection, 94 (44.5%) had moderate, while 18 (8.53%) had mild infection. Overall, 150 (71.1%) infected Diabetic Foot Ulcers (DFUs), 67 (44.6%) and 65 (43.3%) DFUs with moderate infection and severe infection respectively were healed without any amputation.

Conclusion:
Infection was found to be the major cause of amputation in most patients with toe amputation being more common. Early referral of patients to the tertiary care unit and a multidisciplinary approach may help prevent DFI from major and minor amputations.
Comparative Analysis of Different Prognostic Markers in Predicting Outcome in Advanced Heart Failure
Authors: Godhiwala Parth , Kumar Sunil , Acharya Sourya , Patel Mansi 
Published: June 2024

Introduction:Heart failure (HF) is a debilitating condition with an adverse outcome, especially during the advanced stage having higher morbidity and mortality rates. Various parameters have been used as prognostic markers in advanced HF. This study highlights about the comparative analysis of different prognostic markers in predicting mortality in advanced HF.Methods:This prospective observational study was conducted in patients of advanced HF admitted to the department of medicine intensive care unit in a rural tertiary care hospital from 2018 to 2020. Advanced HF was diagnosed using the updated HF Association-European Society of Cardiology criteria. The serum N-terminal pro-B-type natriuretic peptide (NT-proBNP), six-minute walk test (6MWT), left ventricular ejection fraction (LVEF), estimated glomerular filtration rate, and glycosylated hemoglobin type A1c levels were measured on admission. Receiver operating characteristic (ROC) curve was also studied for the above-mentioned variables, and the area under ROC curve (AUROC) was also determined.Results:Seventy-five patients with an average age of 60.55 ± 14.04 years were evaluated. Out of 75, 48 (64%) were male and 27 (36%) were female. There was inhospital mortality in 20 (26.67%) patients. The mean NT-proBNP levels among the mortality group was 9826.95 ± 3485.10 pg/mL, while in nonmortality group, it was 6135.40 ± 2342.77 pg/mL (P= 0.001). The cutoff range in this study for on-admission serum NT-proBNP levels was 8990 pg/mL, with AUROC of 0.81, the sensitivity of 70.0%, and specificity of 90.9%. In multiple regression analysis keeping mortality as the dependent variable, it was seen that variables NT-proBNP, 6MWT (<300 m), and LVEF were significantly associated with mortality.Conclusion:Serum NT-proBNP and 6MWT (<300 m) were important predictors of mortality in advanced HF.
TRACE MATRIKS FLDcircr BENTUK KHUSUS BERPANGKAT DUA
Authors: Rahma Ade Novia , Sukmawati Sri , Rahmawati Rahmawati 
Published: June 2024

Tracking the matrix is ​​the sum of the elements on the main diagonal of the matrix. This study aims to determine the Trace of a specially shaped quadratic FLDcircr matrix. In determining the Trace of a squared FLDcircr matrix, there are a number of steps to be take. First determine the special shape of the to 8x8 FLDcircr, matrix so that the general shape of FLDcircr, is formed to form a special quadratic.Furthermore, from the equations obtained, we can determine the Trace of the FLDcircr matrix in the form of a special quadratic order of the matrix to , Having obtained the general form of Trace from the FLDcircr matrix, we can prove it by direct proof
PENERAPAN POISSON INVERSE GAUSSIAN REGRESSION UNTUK MEMODELKAN LAMA RAWAT INAP PASIEN DEMAM BERDARAH DENGUE (DBD) UPTDK. RSU. HAJI MEDAN PEMERINTAHAN PROVINSI SUMATERA UTARA
Authors: Purqon Khairul , Widyasari Rina , Husein Ismail 
Published: June 2024

Dengue fever is one of the dangerous diseases that can threaten human life if not treated seriously. Dengue hemorrhagic fever is one of the health problems that exist in the community where the number of sufferers tends to increase and the spread is very wide. Dengue hemorrhagic fever (DHF) is a disease caused by infection with the DEN-1, DEN-2, DEN-3 or DEN-4 viruses transmitted to the bite of Aedes aegypti and Aedes Albopictus mosquitoes before it was infected by the dengue virus by dengue sufferers. Aedes aegypti mosquitoes become more infective for 8-12 days after sucking blood from dengue patients before. However, for now only researchers take only a few factors that make the length of stay of dengue patients in UPTDK. RSU. Hajj Medan Government of North Sumtera Province. In this study, the independent variables used were Patient Age Value (), Platelet value (), Leukocyte value (), and Hemoglobin value () in UPTDK. RSU. Haji Medan Government of North Sumtera Province using Poisson Inverse Gaussian Regression (PIGR). Poisson Inverse Gaussian Regression (PIGR) is a form of regression from mixed poisson designed on enumeration data with overdispersion cases. Therefore, research using the Poisson Inverse Gaussian Regression method can be carried out. The Poisson Inverse Gaussian Regression model formed is with a very significant influential variable is the Leukocyte value
Diálogos entre esporte, comunicação, cultura e política
Authors: Follain de Figueiredo Vera Lúcia , Freire Carauta Alexandre Augusto 
Published: June 2024

A Alceu 52 soma-se aos esforços reflexivos em torno dos elos entre a comunicação contemporânea e os estratos sociais, culturais, políticos e econômicos do esporte. Semelhantes estratos configuram um fenômeno multidimensional e, portanto, um substantivo objeto de estudo.
Os 15 textos do dossiê “Estudos contemporâneos em comunicação e esporte” contemplam tal pluralidade e tal relevo social. Foram selecionados pela editora-convidada Leda Costa e pelos editores-convidados Ronaldo Helal e Fausto Amaro.
EMOTIONAL INTELLIGENCE AND FAKE NEWS QUOTIENT OF BPE STUDENTS
Authors: Potenciando Marmee Rochelle Malinao , Cabalquinto Ron Danelle , Duliguez Evander , Labarca Rollen Joie 
Published: June 2024

This descriptive correlational design study aimed to describe the significant relationship between emotional intelligence and the fake news quotient of BPE students. The results from 200 BPE students from the College of Teacher Education of the University of Mindanao revealed the following: the level of emotional intelligence was high; the level of fake news quotient was high; when correlated, there is a significant and moderate positive relationship among the variables. This implies that emotional intelligence could moderately affect the fake news quotient of BPE students, where emotional intelligence will allow them to determine fake news. However, having an average level of emotional intelligence will not only be the factor that influences the determination of fake news. Thus, determining the students' emotional intelligence level provides insight to teachers on how emotional intelligence may affect the fake news quotient of BPE students.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0977/a.php" alt="Hit counter" /></p>
Measuring community disaster resilience in Southern Punjab: a study of 2022 floods in Pakistan
Authors: Aleha Anum , Zahra Syeda Mahwish , Memon Abdul Waheed , Mahar Waqas Ahmed 
Published: June 2024

Pakistan only contributes 1% of the global greenhouse gas emissions. The country’s substantial vulnerability to the effects of climate change was highlighted during the 2022 floods. One-third of the country was underwater, 33 million people were affected, and 8 million were displaced. The destruction caused by the 2010 floods is dwarfed by the disaster's scale in Pakistan. This study discusses the rehabilitation and recovery goals of the affected area, along with additional mitigating strategies. This can be done through resilient and sustainable repairing and upgrading the physical infrastructure. An analysis was done to estimate how resilient this target community is to disaster. Data collection and analysis techniques of the research were adopted. The resilience of the community to disasters was investigated using the Assessment of Resistance of Communities to Natural Disasters (ARC-D) toolkit created by GOAL International. The affected Southern Punjab region was selected, and qualitative and quantitative techniques were employed. Using the toolbox, a structured survey form was created. The findings showed that communities were unaware of their risks and problems and were not provided with the necessary plans and solutions. Specific tools and methods are required to measure the resilience of various communities and social activist groups.
Consumer Behaviour on Electric Vehicles
Authors: L. Sainath Yadav  , D r. T. Vara Lakshmi  , M. Divya  
Published: June 2024

This project aims to map the consumer perception toward e-vehicle in Vadodara city. Every day we come across so many topics and articles which states the importance of E-Vehicles and how government around the world are implementing policies to promote E-Vehicles to reduce the dependences on oil, decrease greenhouse gasses and improve air quality. A major pollutant comes from Metropolitan cities and hence it is important for people living in these cities to understand and do their bit to reduce the consumption of life-threatening gasses and pollutants. This project is aimed to capture the views, sentiments and perception on the awareness and likeliness to buy the vehicles so that sustainability in environment can be maintained. With the increasing concern over environmental sustainability and the need to reduce greenhouse gas emissions, electric vehicles (EVs) have emerged as a promising alternative for conventional gasoline-powered cars. This study investigates the consumer attitude towards EVs as a viable option for mobility.
Kesejahteraan Masyarakat Diukur Melalui Pengagguran, Inflasi dan Pertumbuhan Ekonomi di Kalimantan Tengah, Kalimantan Utara dan Kalimantan Timur
Authors: Pradanimas Aqilla , Lifia Lifia 
Published: June 2024

Welfare of the people is a goal of every region, including Central Kalimantan, North Kalimantan and East Kalimantan. Welfare of the people measured using Human Development Index (HDI). There are many factors that influence welfare of the people. This purpose of study to analyze the effect of unemployment and inflation on welfare of the people with economic growth as an intervening. The research method used quantitative wita data from the Central Bureau of Statistics and Path analysis as an analytical technique. The results of study unemployment has a positive significant effect on welfare of the people, while inflation has a negative significant effect and economic growth has no significant effect. Unemployment has a negative significant effect on ecomic growth, while inflation has a positive significant. And economic growth cannot be an intervening variable. So to improve the welfare of the people it is necessary to play the role of governments in each province to really focus on allocating funds for health, education, employment expansion programs, skills improvement and effective and efficient poverty alleviation programs.
Pengaruh Inflasi dan Angka Pengangguran terhadap Pertumbuhan Ekonomi Melalui Tingkat Kemiskinan 7 Kota/Kabupaten di Jawa Timur
Authors: Farah Salsabila Firda Hayyu , Fakhril Ma’ruf Muhammad , Yuliana Indah , Sri Rahayu Yayuk 
Published: June 2024

The purpose of this study is to analyze the relationship between inflation, unemployment rate, poverty rate and economic growth in East Java province. The introductory chapter focuses on the economic challenges of developing countries, particularly those related to poverty, inflation, and economic growth. The research method uses a descriptive quantitative approach with hypothesis testing using t-values. Data for his seven cities/districts in East Java province were collected by the Central Bureau of Statistics from 2012 to 2022. The results of classical assumption testing indicate that the data are normally distributed, with no multicollinearity, autocorrelation, or heteroscedasticity. The results of the hypothetical analysis show that inflation has no significant impact on poverty, but unemployment has a significant negative impact. Inflation does not have a direct impact on economic growth, but unemployment rate has a negative impact on economic growth. Poverty level does not have a significant impact on economic growth. The conclusion emphasizes the importance of controlling the unemployment rate to reduce poverty and improve economic growth in East Java. Although inflation does not have a direct impact on economic growth, its stability is still important. Suggestions for further research include considering additional variables and gaining a deeper understanding of regional economic dynamics.
Analisis Pengaruh Dimensi Work-Life Balance Terhadap Intensi Turnover Karyawan pada Generasi Milenial (Y)
Authors: Boy Andika Sinaga  , Rikardo E Parapat  
Published: June 2024

The purpose of this research was to find and analyze the influencing factors of turnover in milenial’s generation employees (Y) using work-life balance aspect. This research was carried out quantitatively, using the survey methode with data analysis techniques using multiple linear regression methods. Quaestionnaire as a data collection instrument and distributed online via google form used 109 respondents. The dimensions of measuring the work-life balance aspect are work interference with personal life, work enhancement of personal life, personal life interference with work, personal life enhancement of work, and satisfaction balance. This research results obtained are the work interference with personal life which has significant effect on millennial employee turnover. While the others four dimensions are also quite influential on turnover. For decreasing turnover, companies need to create support policies to create work-life balance by implementing such as flexible working hours and being committed to balancing work and personal lives of employees.
Pengaruh Kualitas Layanan dan Citra Perusahaan Terhadap Kepuasan Konsumen Serta Dampak pada Loyalitas Konsumen Aplikasi Pijar Sekolah: Studi pada SMK Kartika XIX -1
Authors: Vianty Nadhira  , Marheni Eka Saputri  
Published: June 2024

The current development of Information Technology can result in many changes in elements of various fields, one of which is in the world of education. Technological developments in the world of education have experienced many changes in the learning process. With the development of technology through learning platforms, many kinds of increasingly advanced learning methods have emerged, one of which is the emergence of Pijar Sekolah application by PT.Telkom Indonesia, which is a learning media that has very diverse features and of course has been launched with the latest sophistication and formulation, making it easier to develop learning in Indonesia. The purpose of this research is to determine the influence of service quality and company image on customer satisfaction and their impact on school customer loyalty pijar sekolah application at SMK Kartika XIX-1. This research uses quantitative methods with descriptive analysis research type. Sampling was carried out using a probability sampling method, simple random sampling type, with 211 respondents. The data analysis technique uses Partial Least Square Structural Equation Modeling (SEM) with SmartPLS 3 software. Based on the research results, it shows that service quality has a significant effect on customer satisfaction. Company image has a significant effect on customer satisfaction. Service quality has a significant effect on customer loyalty. Company image does not have a significant effect on customer loyalty. Customer satisfaction has a significant effect on customer loyalty. Service quality has a significant effect on customer loyalty through customer satisfaction. Company image has a significant effect on customer loyalty through customer satisfaction.
Sistem Informasi Sebagai Peluang dan Tantangan Dakwah
Authors: Larasati Dwi , Efendi Erwan , Hasibuan Sapriyani , Harahap Rizky Padli , Gumala Randy 
Published: June 2024

Application of a management information system to the Da'wah Organization Management Organization, which entails knowledge of the management information system, its goals, benefits, and features, as well as the Da'wah Organization Organization's management information system, from which we can learn how to apply this In missionary organizations, there is management, which starts with data processing and ends with data programming. Information systems need to be capable of offering useful information to managers, especially for users, in order to support operations and management within an organization in an integrated manner. Today's organizations need the involvement of many more internal parties than they did in the past when it came to their role and involvement in the development and management of information systems.
Keywords : Information System, Opportunities, Dawah
Pengaruh Pemasaran Relasional dan Kepuasan Nasabah terhadap Loyalitas Nasabah
Authors: Amelia Anjani Rizky , Nurbaiti  , Aslami Nuri 
Published: June 2024

This study aims to determine whether or not there is influence of relational marketing and customer satisfaction on customer loyalty at the company AJB BUMIPUTERA 1912 Medan regional office. The methodology used in this study is a quantitative method with an associative approach. The variables in this study are relational marketing and customer satisfaction as independent variables and customer loyalty as the dependent variable. Samples were taken from AJB BUMIPUTERA 1912 customers in the Medan regional office, totaling 95 people. The type of data used is primary data. The data analysis method used is Instrument Test, Classical Assumption Test, Multiple Linear Regression Test, and Hypothesis Test. Based on the results of the adjusted R value obtained from the SPSS processing is 0.825 which means that relational marketing and customer satisfaction can explain the customer loyalty variable of 82.5% and the remaining 17.5% is explained by other variables not examined in this study. Based on the results of the F test analysis, it is known that the value of fcount (222.202) > ftable (3.10) and sig (0.000) < α (0.05). This means proving that relational marketing and customer satisfaction simultaneously have a positive and significant effect on customer loyalty.

Keywords : customer satisfaction, customer loyalty, relational marketing.