bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surveillance and detection of Haemaphysalis longicornis (Acari: Ixodidae) in protected areas from Georgia, USA
Authors: Fausett Eleanor , Kirstein Oscar D , Bellman Stephanie , Long Audrey , Roeske Isabella , Cheng Chun , Piantadosi Anne , Anderson Tavis K , Vazquez-Prokopec Gonzalo M 
Published: May 2024

Abstract
The invasion of the Asian longhorned tick, Haemaphysalis longicornis Neumann, into the United States poses a significant ecological, veterinarian, and public health threat. We conducted a comprehensive tick survey using standard tick flagging protocol for collection over 3 field seasons, March–August, and 56 surveyed sites to identify the presence of H. longicornis in the native ecosystem and prove its establishment according to USDA criteria. Of the total 56 state parks and wildlife management areas (WMA) surveyed, only one was found to be invaded by H. longicornis; detection of H. longicornis occurred at Buck Shoals Wildlife Management area in White County, GA. This site is maintained by the state of Georgia, has no agricultural animals present, and hosts a large white-tailed deer population. After the initial detection of H. longicornis in 2022, an additional field season occurred in 2023, where H. longicornis was confirmed as established based on USDA criteria. The increase in H. longicornis populations from 2021 to 2023 at Buck Shoals WMA points to the rapid spread of this tick within the environment. Our findings provide evidence of the rapid establishment of H. longicornis in the southern edge of suitability for this tick and within the native ecosystem beyond farmlands and private land.
Willingness and ability of existing mosquito control and public health agencies in New Jersey to assume responsibilities for management of ticks and tick-borne disease
Authors: Jordan Robert A , Eisen Lars , Schulze Terry L 
Published: May 2024

Abstract
We conducted surveys of New Jersey mosquito control and public health agencies to determine their willingness and ability to expand or create and maintain publicly funded tick and tick-borne disease (T/TBD) management programs. Nearly all (86%) of 21 county mosquito control agencies (MCAs) completed the survey, while only 25% of the 102 health departments (HDs) responded, probably reflecting traditional agency responsibilities. Although few of either group had formal programs, many were engaged in T/TBD-related activities. Many MCAs rated their ability to assume T/TBD responsibilities as high or moderate, while most HDs rated their capabilities as low. With the exceptions of lack of sustainable funding and possible legal constraints, the groups differed regarding perceived barriers to program creation and maintenance. Both groups envisioned comprehensive programs emphasizing public education, but program priorities differed between the groups. MCAs were willing to include most program activities, while HDs felt that some activities should be the responsibility of other agencies. MCAs were generally more familiar than HDs with tick control methods and while both groups would include control in a comprehensive program, both would limit control to public lands. Estimated program costs varied widely, probably reflecting responding agency size and complexity of envisioned programs. These results in a state with a system of existing agencies staffed by highly competent professionals suggest that more than simply additional funding (e.g., established guidelines for tick control and surveillance) is needed to create a network of practice necessary to address the growing incidence of TBD.
Trends in imported infections among migrants and travellers to Spain: a decade of analysis through the +Redivi network (2012–2022)
Authors: Alkaissy Yam , Serre-Delcor Nuria , Vicente Marta Arsuaga , Molina Israel , Norman Francesca F , Goikoetxea Ane Josune , de Dios Begoña , Torrús Diego , Navarrete Lorite Miguel Nicolás , Rodríguez-Guardado Azucena , Lombide Itxaso , Calabuig Eva , Muriel Alfonso , Perez-Molina Jose A ,   on behalf of +Redivi network
Published: May 2024

Abstract

Background
High-speed global travel, increased trade, world population growth, migration, urbanization and climate change have favoured the emergence and spread of pathogens. We aimed to analyse the evolution of imported infections in Spain during 2012–2022 and the potential impact of some of the abovementioned factors on differential morbidity patterns.

Methods
In this retrospective study (January 2012 to December 2022), we analysed data collected by the +Redivi network across 25 health centres. The network’s standardised database records new cases of imported infections, including patient demographics, travel history, pre-travel advice and diagnostic information. To assess outcome rates over time and potential interactions, we constructed penalized weighted models to reduce the bias related to a low event rate and used weighted logistic regression for morbidity outcomes.

Results
We recorded 25 632 episodes, comprising 13 913 migrants, 4047 visiting friends and relatives (VFR) immigrants, 392 VFR travellers and 7280 travellers. Most immigrants came from South America (48.3%), Sub-Saharan Africa (28.5%), North Africa (6.6%), South Central Asia (5.4%) and Central America/Caribbean (5.3%). The most common regions visited by travellers were Sub-Saharan Africa (33.5%), South America (24.5%), Central America/Caribbean (13.5%), Southeast Asia (12%) and South Central Asia (10%). The proportion of diagnoses of malaria, strongyloidiasis and unspecified self-limiting febrile syndrome &lt; 3 weeks remained unchanged during the study period. An increased frequency of diagnosis was reported for schistosomiasis, blastocystosis, giardiasis, dengue, diarrhoea, new cases of HIV, latent and pulmonary tuberculosis, whereas a decrease was reported for syphilis, chikungunya fever, Chagas disease and eosinophilia. We detected interactions between time and sex or type of participant across the different diagnoses.

Conclusions
Our study underscores the importance of epidemiological data in understanding infectious diseases dynamics among travellers and migrants, emphasizing how demographic shifts, migration trends and healthcare policies affect disease profiles. Comprehensive data play an essential role in enhancing public health policies and travel advice.
Nietzsche and the Significance of Genealogy
Authors: Prescott-Couch Alexander 
Published: May 2024

Abstract
How is Nietzsche’s genealogy of morality relevant to his revaluation of values? I consider and reject three accounts: contingency accounts, pedigree accounts, and unmasking accounts. I then propose an alternative account. On this view, Nietzsche provides a ‘deconstructive genealogy’ that indicates whether and where we should expect to find unity in our current moral practices. Moreover, Nietzsche’s history contributes to a critique of contemporary morality because it reveals that morality is unlikely to have the kind of unity required by many of its defenders. After explaining and defending this account of genealogical critique in GM, I show how it can be generalized to domains besides morality.
The MAGPI survey: evolution of radial trends in star formation activity across cosmic time
Authors: Mun Marcie , Wisnioski Emily , Battisti Andrew J , Mendel J Trevor , Ellison Sara L , Taylor Edward N , Lagos Claudia D P , Harborne Katherine E , Foster Caroline , Croom Scott M , Bellstedt Sabine , Barsanti Stefania , Gupta Anshu , Valenzuela Lucas M , Chen Qian-Hui , Grasha Kathryn , Mukherjee Tamal , Park Hye-Jin , Sharda Piyush , Sweet Sarah M , Remus Rhea-Silvia , Zafar Tayyaba 
Published: May 2024

ABSTRACT
Using adaptive optics with the Multi-Unit Spectroscopic Explorer on the Very Large Telescope, the Middle Ages Galaxy Properties with Integral Field Spectroscopy survey allows us to study the spatially resolved Universe at a crucial time of ∼4 Gyr ago (z ∼ 0.3) when simulations predict the greatest diversity in evolutionary pathways for galaxies. We investigate the radial trends in the star formation (SF) activity and luminosity-weighted stellar ages as a function of offset from the star-forming main sequence (SFMS) for a total of 294 galaxies. Using both Hα emission and the 4000 Å break (i.e. D4000) as star formation rate (SFR) tracers, we find overall flat radial profiles for galaxies lying on and above the SFMS, suggestive of physical processes that enhance/regulate SF throughout the entire galaxy disc. However, for galaxies lying below the SFMS, we find positive gradients in SF suggestive of inside–out quenching. Placing our results in context with results from other redshift regimes suggests an evolution in radial trends at z ∼ 0.3 for SF galaxies above the SFMS, from uniformly enhanced SF at z ∼ 1 and ∼ 0.3 to centrally enhanced SF at z ∼ 0 (when averaged over a wide range of mass). We also capture higher local SFRs for galaxies below the SFMS compared to that of z ∼ 0, which can be explained by a larger population of quenched satellites in the local Universe and/or different treatments of limitations set by the D4000–sSFR relation.
Faster cosmological analysis with power spectrum without simulations
Authors: Lai Yan , Howlett Cullan , Davis Tamara M 
Published: May 2024

ABSTRACT
Future surveys could obtain tighter constraints on the cosmological parameters with the galaxy power spectrum than with the cosmic microwave background. However, the inclusion of multiple overlapping tracers, redshift bins, and more non-linear scales means that generating the necessary ensemble of simulations for model-fitting presents a computational burden. In this work, we combine full-shape fitting of galaxy power spectra, analytical covariance matrix estimates, the massively optimized parameter estimation and data compression (MOPED) method, and the Taylor expansion interpolation of the power spectrum for the first time to constrain the cosmological parameters directly from a state-of-the-art set of galaxy clustering measurements. We find it takes less than a day to compute the analytical covariance while it takes several months to calculate the simulated ones. Combining MOPED with the Taylor expansion interpolation of the power spectrum, we can constrain the cosmological parameters in just a few hours instead of a few days. We also find that even without a priori knowledge of the best-fitting cosmological or galaxy bias parameters, the analytical covariance matrix with the MOPED compression still gives consistent cosmological constraints to within 0.1σ after two iterations. Therefore, the pipeline we have developed here can significantly speed up the analysis for future surveys.
Turbulence statistics of H i clouds entrained in the Milky Way’s nuclear wind
Authors: Gerrard Isabella A , Noon Karlie A , Federrath Christoph , Di Teodoro Enrico M , Marchal Antoine , McClure-Griffiths N M 
Published: May 2024

ABSTRACT
The interstellar medium (ISM) is ubiquitously turbulent across many physically distinct environments within the Galaxy. Turbulence is key in controlling the structure and dynamics of the ISM, regulating star formation, and transporting metals within the Galaxy. We present the first observational measurements of turbulence in neutral hydrogen entrained in the hot nuclear wind of the Milky Way. Using recent MeerKAT observations of two extra-planar H i clouds above (gal. lat.$\, \sim 7.0^{\circ }$) and below (gal. lat.$\, \sim -3.9^{\circ }$) the Galactic disc, we analyse centroid velocity and column density maps to estimate the velocity dispersion (σv,3D), the turbulent sonic Mach number ($\mathcal {M}$), the volume density dispersion ($\sigma _{\rho /\rho _0}$), and the turbulence driving parameter (b). We also present a new prescription for estimating the spatial temperature variations of H i in the presence of related molecular gas. We measure these turbulence quantities on the global scale of each cloud, but also spatially map their variation across the plane-of-sky extent of each cloud by using a roving kernel method. We find that the two clouds share very similar characteristics of their internal turbulence, despite their varying latitudes. Both clouds are in the sub-to-trans-sonic Mach regime, and have primarily compressively driven (b ∼ 1) turbulence. Given that there is no known active star formation present in these clouds, this may be indicative of the way the cloud–wind interaction injects energy into the entrained atomic material on parsec scales.
Main-belt and Trojan asteroid phase curves from the ATLAS survey
Authors: Robinson James E , Fitzsimmons Alan , Young David R , Bannister Michele , Denneau Larry , Erasmus Nicolas , Lawrence Amanda , Siverd Robert J , Tonry John 
Published: May 2024

ABSTRACT
Sparse and serendipitous asteroid photometry obtained by wide field surveys such as the Asteroid Terrestrial-impact Last Alert System (ATLAS) is a valuable resource for studying the properties of large numbers of small Solar System bodies. We have gathered a large data base of ATLAS photometry in wideband optical cyan and orange filters, consisting of 9.6 × 107 observations of 4.5 × 105 main belt asteroids and Jupiter Trojans. We conduct a phase curve analysis of these asteroids considering each apparition separately, allowing us to accurately reject outlying observations and to remove apparitions and asteroids not suitable for phase curve determination. We obtain a data set of absolute magnitudes and phase parameters for over 100 000 selected asteroids observed by ATLAS, $\sim 66\, 000$ of which had sufficient measurements to derive colours in the ATLAS filters. To demonstrate the power of our data set we consider the properties of the Nysa–Polana complex, for which the ATLAS colours and phase parameters trace the S-like and C-like compositions amongst family members. We also compare the properties of the leading and trailing groups of Jupiter Trojans, finding no significant differences in their phase parameters or colours as measured by ATLAS, supporting the consensus that these groups were captured from a common source population during planetary migration. Furthermore, we identify ∼9000 asteroids that exhibit large shifts in derived absolute magnitude between apparitions, indicating that these objects have both elongated shapes and spin axes with obliquity ∼90 degrees.
Blood transfusion in the care of patients with visceral leishmaniasis: a review of practices in therapeutic efficacy studies
Authors: Dahal Prabin , Singh-Phulgenda Sauman , Wilson James , Cota Glaucia , Ritmeijer Koert , Musa Ahmed , Alves Fabiana , Stepniewska Kasia , Guerin Philippe J 
Published: May 2024

AbstractBlood transfusion remains an important aspect of patient management in visceral leishmaniasis (VL). However, transfusion triggers considered are poorly understood. This review summarises the transfusion practices adopted in VL efficacy studies using the Infectious Diseases Data Observatory VL clinical trials library. Of the 160 studies (1980–2021) indexed in the IDDO VL library, description of blood transfusion was presented in 16 (10.0%) (n=3459 patients) studies. Transfusion was initiated solely based on haemoglobin (Hb) measurement in nine studies, combining Hb measurement with an additional condition (epistaxis/poor health/clinical instability) in three studies and the criteria was not mentioned in four studies. The Hb threshold range for triggering transfusion was 3–8 g/dL. The number of patients receiving transfusion was explicitly reported in 10 studies (2421 patients enrolled, 217 underwent transfusion). The median proportion of patients who received transfusion in a study was 8.0% (Interquartile range: 4.7% to 47.2%; range: 0–100%; n=10 studies). Of the 217 patients requiring transfusion, 58 occurred before VL treatment initiation, 46 during the treatment/follow-up phase and the time was not mentioned in 113. This review describes the variation in clinical practice and is an important initial step in policy/guideline development, where both the patient's Hb concentration and clinical status must be considered.
SKP2‐mediated ubiquitination and degradation of KLF11 promotes osteoarthritis via modulation of JMJD3/NOTCH1 pathway
Authors: Huang Yuanchi , Pan Wenjie , Ma Jianbing 
Published: May 2024

AbstractOsteoarthritis (OA) is the main cause of cartilage damage and disability. This study explored the biological function of S‐phase kinase‐associated protein 2 (SKP2) and Kruppel‐like factor 11 (KLF11) in OA progression and its underlying mechanisms. C28/I2 chondrocytes were stimulated with IL‐1β to mimic OA in vitro. We found that SKP2, Jumonji domain‐containing protein D3 (JMJD3), and Notch receptor 1 (NOTCH1) were upregulated, while KLF11 was downregulated in IL‐1β‐stimulated chondrocytes. SKP2/JMJD3 silencing or KLF11 overexpression repressed apoptosis and extracellular matrix (ECM) degradation in chondrocytes. Mechanistically, SKP2 triggered the ubiquitination and degradation of KLF11 to transcriptionally activate JMJD3, which resulted in activation of NOTCH1 through inhibiting H3K27me3. What's more, the in vivo study found that KLF11 overexpression delayed OA development in rats via restraining apoptosis and maintaining the balance of ECM metabolism. Taken together, ubiquitination and degradation of KLF11 regulated by SKP2 contributed to OA progression by activation of JMJD3/NOTCH1 pathway. Our findings provide promising therapeutic targets for OA.
Acetylcholinesterase is regulated by exposure of ultraviolet B in skin keratinocytes: A potential inducer of cholinergic urticaria
Authors: Wu Qiyun , Xia Yingjie , Guo Maggie Suisui , Au Tsz Yu , Yuen Gary K. W. , Kong Ivan , Wang Zhengqi , Lin Yingyi , Dong Tina T. X. , Tsim Karl W. K. 
Published: May 2024

AbstractCholinergic urticaria is a dermatological disease characterized by the presence of large patches of red skin and transient hives triggered by factors, such as exercise, sweating, and psychological tension. This skin problem is hypothesized to be attributed to a reduced expression of acetylcholinesterase (AChE), an enzyme responsible for hydrolyzing acetylcholine (ACh). Consequently, ACh is thought to the leak from sympathetic nerves to skin epidermis. The redundant ACh stimulates the mast cells to release histamine, triggering immune responses in skin. Here, the exposure of ultraviolet B in skin suppressed the expression of AChE in keratinocytes, both in in vivo and in vitro models. The decrease of the enzyme was resulted from a declined transcription of ACHE gene mediated by micro‐RNAs, that is, miR‐132 and miR‐212. The levels of miR‐132 and miR‐212 were markedly induced by exposure to ultraviolet B, which subsequently suppressed the transcriptional rate of ACHE. In the presence of low level of AChE, the overflow ACh caused the pro‐inflammatory responses in skin epidermis, including increased secretion of cytokines and COX‐2. These findings suggest that ultraviolet B exposure is one of the factors contributing to cholinergic urticaria in skin.
Long-term Follow-up of Hand-degloving Injury Treated by Conventional Methods
Authors: Ishii Hana , Moriya Koji , Narisawa Hiroko , Tsubokawa Naoto , Maki Yutaka , Shimada Kenichi 
Published: May 2024

Summary:
Despite medical advances, degloving injury remains one of the most difficult traumatic injuries to treat. The conventional method for treating degloving injury of the hand is reconstruction with a groin flap. However, few reports have described the mid- or long-term functional and aesthetic outcomes after a hand reconstruction with a groin flap. This case report describes a 68-year-old woman with no specific medical history who presented with a severe degloving injury of the right hand, caused by a roller machine. The area of skin loss was covered with a pedicled groin flap that was separated after 3 weeks. Five years after the reconstruction, she had poor functional and aesthetic outcomes. The Japanese Society for Surgery of the Hand version of the Quick Disabilities of the Arm, Shoulder and Hand score was 57.5; the Hand20 score was 60; and the Michigan Hand Outcomes Questionnaire score was 37.5. The static two-point discrimination of the index and middle fingers was more than 15 mm, and Semmes-Weinstein monofilament examination showed that the sensation thresholds of these fingers were purple and blue. The range of motion was 10-degree angle of extension and 60-degree angle of flexion for the metacarpophalangeal joints of the index and middle fingers. Grip strength was 0.0 kg; pulp pinch strength of the index and middle fingers was 1.1 and 0.8 kg, respectively; and side pinch of the index and middle fingers was 0.1 and 0.7 kg, respectively.
Active Occipital Motion with Digipressure as Preoperative Screening in Migraine Surgery
Authors: Raposio Edoardo , Raposio Giorgio , Baldelli Ilaria , Peled Ziv 
Published: May 2024

Background:Modern surgical therapy of chronic headaches/migraines is essentially based on the release/neurolysis of extracranial nerves, which, when compressed or inflamed, act as trigger points and, as such, trigger headache attacks. The aim of this article was to describe a novel maneuver we use as an aid in the preoperative planning of occipital trigger sites.Methods:In the period of January 2021–September 2023, we operated on 32 patients (11 men, 21 women, age range: 26–68 years), who underwent migraine surgery for occipital trigger point release. All patients were evaluated using the described preoperative maneuver. In a dedicated card, the levels of tenderness at each point were marked accordingly, differentiating them by intensity as nothing (−), mild (+), medium (++), or high (+++). Patients were then operated on at the points corresponding only to the ++ and +++ signs.Results:At 6-month follow-up, we observed significant improvement (>50%) in 29 patients (91%), with complete recovery in 25 patients (78%).Conclusions:In our experience, the maneuver described, in addition to being very simple, has been shown to have good sensitivity and reproducibility. We therefore recommend its use, especially for those surgeons beginning their practice in this particular area of plastic surgery.