bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of an Elaborated Heliquinomycin Isocoumarin Moiety.
Authors: Thrash Thomas P. , Welton Thomas D. , Behar Victor 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of the C1—C12‐Dihydropyran Segment of the Antitumor Agent Laulimalide by Ring Closing Metathesis.
Authors: Mulzer Johann , Hanbauer Martin 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (Z)‐7‐Heneicosene and (Z)‐7‐Tricosene via Organoboranes. Part 5.
Authors: Battu Raminderjit S. , Dhillon Ranjit S. , Singh Jasvinder 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 9‐Methylgermacrene‐B is Confirmed as the Sex Pheromone of the Sandfly Lutzomyia longipalpis from Lapinha, Brazil, and the Absolute Stereochemistry Defined as S.
Authors: Hamilton J. Gordon C. , Hooper Antony M. , Ibbotson Helen C. , Kurosawa Satoshi , Mori Kenji , Muto Shin‐etsu , Pickett John A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbon Nanocage Structures Formed by One‐Dimensional Self‐Organization of Gold Nanoparticles.
Authors: Oku Takeo , Suganuma Katsuaki 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of Monodispersed Pd/Ni Nanoparticles.
Authors: Teranishi Toshiharu , Miyake Mikio 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Variations and Magnetic Studies of Polymetallic Cages
Authors: Brechin Euan K. , Graham Alasdair , Grant Craig M. , Murrie Mark , Parsons Simon , Winpenny Richard E. P. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Thermal and Transport Studies on Non‐Fermi Liquid Behavior in CeNi2Ge2
Authors: Aoki Yuji , Urakawa Jun , Sugawara Hitoshi , Sato Hideyuki , Fukuhara Tadashi , Maezawa Kunihiko 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1‐Metalla‐1,3,5‐hexatrienes and Related Compounds
Authors: Aumann Rudolf 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Triphenylmethyl Group — A Kinetically Stabilizing Substituent and Protecting Group in Organophosphorus Chemistry
Authors: Plack Volker , Schmutzler Reinhard 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Organophosphorus Compounds in Terms of Elemental Phosphorus, Sulfur and Their Derivatives
Authors: Batyeva Elvira S. , Nizamov Il'Yas S. , Kursheva Lidiya I. , Frolova Liliya V. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Chiral Sulfoxides in Enantioselective Synthesis of Diols and Total Synthesis of Natural Products
Authors: Solladie Guy 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Indium‐Mediated Organometallic Reactions in Aqueous Media: The Nature of the Allylindium Intermediate
Authors: Keh Charlene C. K. , Li Chao‐Jun 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure, Properties and Reactivity of the FeIIFeIII and ZnIIFeIII Purple Acid Phosphatases
Authors: Twitchett Mark B. , Sykes Geoffrey A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Transcoronary Infusion of Bone Marrow Derived Multipotent Stem Cells to Preserve Left Ventricular Geometry and Function After Myocardial Infarction
Authors: Boonbaichaiyapruck Sarana , Pienvichit Pavit , Limpijarnkij Thosapol , Rerkpattanapipat Pairoj , Pongpatananurak Apichai , Saelee Ratchanee , Ungkanont Artit , Hongeng Suradej 
Published: June 2010

AbstractBackgroundMyocardial damage after myocardial infarction (MI) was deemed irreversible after late reperfusion. Administration of multipotent stem cell (MSC) into such infarct may regenerate the myocardium and capillary network.HypothesisTranscoronary infusion of bone marrow derived multipotent stem cells into infarcted related artery after acute myocardial infarction is feasible, safe and improve left ventricular function.MethodsWe conducted a pilot study in patients who survived ST‐elevation MI with late reperfusion therapy and remained hemodynamically stable. Bone marrow derived MSC was infused into a patent infarct‐related coronary artery during brief low pressure (2 atm) balloon inflation. A 3‐T gadolinium‐based MRI was performed at baseline and 8 weeks later to evaluate infarct area and LV function.ResultsWe enrolled 10 patients, age 63.8 ± 2.8 years 5.2 ± 4.12 × 106 MSC were infused via coronary artery 24.8 ± 16 days after infarction. The procedures were successful in all patients without any in‐hospital event. Infarct size by MRI decreased by 5.84% (P = .018) over 8 weeks. Mean baseline left ventricular ejection fraction (LVEF) was 44.1% ± 9% and was 46.3% ± 9% at 8 weeks (P = .34). A trend of smaller LV end‐systolic volume with 65.02 ± 18.2 ml vs 63.04 ± 21.89 ml (P = .09) with no change of LV end‐diastolic volume observed.ConclusionMSC infusion into coronary circulation was feasible and safe after myocardial infarction. Infarct size was reduced with preservation of LV geometry. Copyright © 2010 Wiley Periodicals, Inc.
In Vitro Cytotoxic‐Active Platinum(II) Complexes Derived from Carboplatin and Involving Purine Derivatives
Authors: Dvořák Lukáš , Popa Igor , Štarha Pavel , Trávníček Zdeněk 
Published: June 2010

AbstractSix platinum(II) complexes of the general formula [Pt(cbdc)(HLn)2] (1–6; cbdc = cyclobutane‐1,1‐dicarboxylate and HL1–HL6 = benzyl‐substituted 6‐benzylamino‐2‐chloro‐9‐isopropylpurine derivatives) have been synthesized by the reaction of [Pt(cbdc)(dmso)2] with the corresponding HLn compound. The prepared complexes were characterized by elemental analysis and FTIR, Raman and NMR (1H, 13C, 15N and 195Pt) spectroscopy. Based on the results of these techniques, it can be concluded that the central PtII atom of the complexes 1–6 is coordinated to two oxygen atoms originating from the cyclobutane‐1,1‐dicarboxylate group and to two nitrogen atoms from two HLn molecules, that is, having a PtN2O2 donor set. Detailed multinuclear and two‐dimensional NMR studies indicated the N‐7 atom to be the coordination site of the purine derivatives. The coordination mode was proven by a single‐crystal X‐ray analysis of the [Pt(cbdc)(dmso)(HL7)]·H2O (7a·H2O) intermediate [HL7 = 2‐chloro‐6‐(2‐methoxybenzyl)amino‐9‐isopropylpurine]. The geometry is slightly distorted square‐planar and the central PtII atom is coordinated to one bidentate cyclobutane‐1,1‐dicarboxylate dianion, one dmso molecule through the sulfur atom and one HL7 molecule through the N‐7 atom of the purine ring, that is, with a PtNO2S donor set. The complexes 1–6 were tested for their in vitro cytotoxicity against K‐562 (chronic myelogenous leukaemia) and MCF7 (breast adenocarcinoma) human cancer cell lines. Values of IC50 (drug concentrations lethal for 50 % of the tumour cells) ranged from 4.5 to 14.1 μM for the K‐562 cells and from 4.3 to 21.0 μM for the MCF7 cells. The in vitro cytotoxicities were in several cases comparable or even higher than those of therapeutically used platinum‐based anticancer drugs, that is, cisplatin, carboplatin andoxaliplatin.
Radical Reduction of Epoxides Using a Titanocene(III)/Water System: Synthesis of β‐Deuterated Alcohols and Their Use as Internal Standards in Food Analysis
Authors: Jiménez Tania , Campaña Araceli G. , Bazdi Btissam , Paradas Miguel , Arráez‐Román David , Segura‐Carretero Antonio , Fernández‐Gutiérrez Alberto , Oltra J. Enrique , Robles Rafael , Justicia José , Cuerva Juan M. 
Published: June 2010

AbstractWe describe a comprehensive study into the Cp2TiCl‐mediated reductive epoxide ring opening using either water as a hydrogen source or deuterium oxide as a deuterium source. The remarkable chemical profile of this reaction allows access to alcohols with anti‐Markovnikov regiochemistry from different epoxides. The use of D2O as a deuterium source leads to an efficient synthesis of β‐deuterated alcohols, including a deuterated sample of tyrosol, a bioactive compound contained in the leaves of the olive, which was successfully applied as an internal standard in food analysis.
Acid‐Catalyzed Cascade Reactions of Enaminones with Aldehydes: C–H Functionalization To Afford 1,4‐Dihydropyridines
Authors: Yang Jingyu , Wang Chengyu , Xie Xin , Li Hongfeng , Li Yanzhong 
Published: June 2010

AbstractAn efficient acid‐catalyzed approach to the synthesis of functional 1,4‐dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.
A Copper(II) Ion‐Selective Potentiometric Sensor Based on N,N′,N″,N′′′‐Tetrakis(2‐pyridylmethyl)‐1,4,8,11‐tetraazacyclotetradecane in PVC Matrix
Authors: Petković B. B. , Sovilj S. P. , Budimir M. V. , Simonović R. M. , Jovanović V. M. 
Published: June 2010

AbstractThe simple PVC‐based membrane containing N,N′,N″,N′′′‐tetrakis(2‐pyridylmethyl)‐1,4,8,11‐tetraazacyclotetradecane (tpmc) as an ionophore and dibutyl phthalate as a plasticizer, directly coated on a glassy carbon electrode was examined as a new sensor for Cu2+ ions. The potential response was linear within the concentration range of 1.0×10−1–1.0×10−6 M with a Nernstian slope of 28.8 mV/decade and detection limit of 7.0×10−7 M. The electrode was used in aqueous solutions over a wide pH range (1.3–6). The sensor exhibited excellent selectivity for Cu2+ ion over a number of cations and was successfully used in its determination in real samples.
Stripping Voltammetric Determination of As(III) in Natural Water Samples Containing Surface Active Compounds
Authors: Grabarczyk Malgorzata 
Published: June 2010

AbstractA cathodic stripping voltammetric method for determination of As(III) using Hg electrode in water samples containing high concentrations of surfactants is described. The linear calibration plot for As(III) was achieved in the simultaneous presence of 1 mg L−1 anionic, 2 mg L−1 cationic and 2 mg L−1 nonionic surfactants for an accumulation time of 30 s in the range 1×10−8 to 1×10−5 mol L−1, the detection limit for accumulation time of 3 hours was about 2.6×10−9 mol L−1. The developed method was successfully applied to As(III) determination in five natural water samples with satisfactory results.
Temporal correlations and clustering of landslides
Authors: Witt Annette , Malamud Bruce D. , Rossi Mauro , Guzzetti Fausto , Peruccacci Silvia 
Published: June 2010

AbstractThis paper examines temporal correlations and temporal clustering of a proxy historical landslide time series, 2255 reported landslides 1951–2002, for an area in the Emilia‐Romagna Region, Italy. Landslide intensity is measured by the number of reported landslides in a day (DL) and in an ‘event’ (Sevent) of consecutive days with landsliding. The non‐zero values in both time seriesDLandSeventare unequally spaced in time, and have heavy‐tailed frequency‐size distributions. To examine temporal correlations, we use power‐spectral analysis (Lomb periodogram) and surrogate data analysis, confronting our originalDLandSeventtime series with 1000 shuffled (uncorrelated) versions. We conclude that the landslide intensity seriesDLhas strong temporal correlations andSeventhas likely temporal correlations. To examine temporal clustering inDLandSevent, we consider extremes over different landslide intensity thresholds. We first examine the statistical distribution of interextreme occurrence times, τ, and find Weibull distributions with parameter γ << 1·0 [DL] and γ < 1·0 [Sevent]; thusDLandSeventeach have temporal correlations, butSeventto a lesser degree. We next examine correlations between successive interextreme occurrence times, τ. Using autocorrelation analysis applied to τ, combined with surrogate data analysis, we find forDLlinear correlations in τ, but forSeventinconclusive results. However, using Kendall's rank correlation analysis we find for bothDLandSeventthe series of τ are strongly correlated. Finally, we apply Fano Factor analysis, finding for bothDLandSeventthe timings of extremes over a given threshold exhibit a fractal structure and are clustered in time. In this paper, we provide a framework for examining time series where the non‐zero values are strongly unequally spaced and heavy‐tailed, particularly important in the Earth Sciences due to their common occurrence, and find that landslide intensity time series exhibit temporal correlations and clustering. Many landslide models currently are designed under the assumption that landslides are uncorrelated in time, which we show is false. Copyright © 2010 John Wiley & Sons, Ltd.
Patterns of organic contaminants in eggs of an insectivorous, an omnivorous, and a piscivorous bird nesting on the Hudson River, New York, USA
Authors: Custer Christine M. , Custer Thomas W. , Dummer Paul M. 
Published: June 2010

AbstractBelted kingfisher (Ceryle alcyon), spotted sandpiper (Actitus macularia), and tree swallow (Tachycineta bicolor) eggs were collected in 2004 from the upper Hudson River, New York, USA. This area is one of the most polychlorinated biphenyl (PCB)-contaminated locations in North America. Multivariate analyses indicated among species differences in the concentration and composition of PCB congeners, polychlorinated dibenzo-p-dioxin (PCDD), and dibenzofuran (PCDF, PCDD-F when combined with PCDDs) congeners, and chlorinated pesticides. Total PCB concentrations followed the typical food chain biomagnification paradigm of higher concentrations in piscivorous bird eggs and lower concentrations in eggs of species that feed at lower trophic levels. Concentrations in the insectivorous swallows (geometric mean = 6.8 µg/g wet wt) were approximately half the concentrations present in the piscivorous kingfisher (11.7 µg/g) or omnivorous sandpiper (12.6 µg/g). In contrast, PCB toxic equivalents (TEQs) were higher in swallows (1,790 pg/g wet wt) than in either kingfishers (776 pg/g) or sandpipers (881 pg/g). This difference can be mainly attributed to higher PCB77 concentrations in swallows relative to the other two species. Also contrary to the accepted food-chain paradigm, the sum of PCDD-F concentrations and the sum of their TEQs were higher in swallows than in either sandpipers or kingfishers. Metabolic pathway differences in the respective food chains of the three species probably accounted for the differences observed in PCB TEQ, total PCDD-F, and PCDD-F TEQ concentrations among species. Environ. Toxicol. Chem. 2010;29:2286–2296. © 2010 SETAC
Conditional β-Catenin Loss in Mice Promotes Chemical Hepatocarcinogenesis: Role of Oxidative Stress and Platelet-Derived Growth Factor Receptor α/Phosphoinositide 3-Kinase Signaling†
Authors: Zhang Xu-Feng , Tan Xinping , Zeng Gang , Misse Amalea , Singh Sucha , Kim Youngsoo , Klaunig James E. , Monga Satdarshan P. S. 
Published: June 2010

Abstract

Activation of β-catenin, the central effector of the canonical Wnt pathway and a recognized oncogene, has been implicated in hepatocellular carcinoma. We examined

N

-nitrosodiethylamine (DEN)-induced tumorigenesis in hepatic β-catenin conditional knockout mice (β-cat KO). Male β-cat KO and age- and sex-matched littermate controls were given a single intraperitoneal DEN injection and followed for 6-12 months for hepatic tumors. Hepatic tumors were characterized for histology, proliferation, apoptosis, oxidative stress, and specific proteins by way of western blot, immunohistochemistry, and coprecipitation studies. For

in vivo

tumor intervention studies, specific inhibitors were administered intraperitoneally or through drinking water. Intriguingly, β-cat KO mice showed a paradoxical increase in susceptibility to DEN-induced tumorigenesis. This accelerated tumorigenesis is due to increased injury and inflammation, unrestricted oxidative stress, fibrosis, and compensatory increase in hepatocyte proliferation secondary to platelet-derived growth factor receptor α (PDGFRα)/phosphoinositide 3-kinase (PIK3CA)/Akt activation and c-Myc overexpression.

In vitro

suppression of β-catenin expression in hepatoma cells led to enhanced PDGFRα expression, which was abrogated in the presence of nuclear factor κB (NF-κB) inhibitor. Daily treatment of 6-month-old DEN-exposed β-cat KO with PDGFRα inhibitor dramatically reduced tumor numbers and size. Inclusion of

N

-acetyl-L-cysteine, a known antioxidant and NF-κB inhibitor, in the drinking water led to complete abolition of tumorigenesis in DEN-exposed β-cat KO.

Conclusion:

Loss of β-catenin impairs the liver's ability to counteract DEN-induced oxidative stress and enhances tumorigenesis through PDGFRα/PIK3CA/Akt signaling. Blockade of PDGFRα or oxidative stress dramatically affects β-catenin–deficient tumorigenesis. Also, hepatoma cells use PDGFRα/PIK3CA signaling as an escape mechanism following β-catenin suppression, and their sequential suppression profoundly impedes tumor proliferation.
Immune reconstitution of B‐cell lymphoma patients receiving CHOP‐based chemotherapy containing rituximab
Authors: Kurokawa Toshiro , Hase Makiko , Tokuman Naoko , Yoshida Takashi 
Published: June 2010

AbstractSixty‐six B‐cell lymphoma patients were treated with a CHOP‐based chemotherapy containing rituximab (R‐CHOP‐like regimen). Immune reconstitution was assessed by measuring lymphocyte subsets and immunoglobulins. Fifty‐five patients (83.3%) underwent six cycles of the R‐CHOP‐like regimen. CD19+ and CD20+ cells were completely eliminated from the peripheral blood after one cycle of the R‐CHOP‐like regimen; they were detected again 6 months after the therapy. One year after the therapy, B‐cell numbers recovered to their level at diagnosis and almost doubled 2 years after the therapy. The lowest numbers of CD3+, CD8+ and CD56+ cells were seen after three cycles of the regimen, but continued to increase until 1 year after the therapy, remaining stable thereafter. CD4+ T‐cells were at their lowest after six cycles of the regimen and recovered slowly for 2 years after the therapy; however, their numbers were still lower than that at diagnosis. Immunoglobulins decreased over six cycles of the R‐CHOP‐like regimen and then recovered gradually for 2 years after the therapy. The percentage of IgG, IgA and IgM 2 years after the therapy compared with those at diagnosis was 93.9%, 90.1%, 76.3%, respectively. Twelve infectious complications occurred which consisted of three febrile neutropenia, three Herpes Zoster, two tympanitis, two Pneumocystis jiroveci pneumonia and two hepatitis B virus reactivation. B‐cells required 1 year and CD4+ T‐cells and immunoglobulins needed 2 years to recover after the therapy. Copyright © 2010 John Wiley & Sons, Ltd.