bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetic and thermodynamic study of inter‐ and intramolecular proton transfer in N′‐acetyl formohydrazide tautomers
Authors: Tavakol Hossein 
Published: October 2010

AbstractNine tautomers and eleven possible tautomeric interconversions of N′‐acetyl formohydrazide have been studied at B3LYP/6‐311++G** level of theory. From these calculations, optimized geometries, molecular parameters, IR frequencies, NMR chemical shifts, and energetic results are obtained. In all tautomers except tautomers 4, E isomer is more stable than Z isomer. Energetic data were used to calculate the energy barriers of tautomeric interconversions and very high energy barriers were obtained for all tautomeric interconversions. Moreover, study of solvent effects on relative stabilities of tautomers and transition states showed that they are similar to those in the gas phase. In addition, intermolecular proton transfer with the assistance of one to three water molecules has been studied and the results showed that activation barriers in water‐assisted tautomerism are in general lower than those in the gas phase. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
Calculations of the infrared and Raman spectra of simple thiols and thiol–water complexes
Authors: Kieninger Martina , Ventura Oscar N. 
Published: October 2010

AbstractThe frequencies and intensities of infrared and Raman spectra of H2S, CH3SH, CH3CH2SH, and CH2CHCH2SH, isolated and complexed with one water molecule acting as a proton acceptor were calculated at the ab initio and density functional level. Hartree‐Fock, MP2 and CCSD(T) methods were used both for the geometry optimization and spectra calculations at the molecular orbital level. The B3LYP, PBE0, and M06 exchange‐correlation potentials were employed to calculate the same properties at the DFT level. Both Pople basis sets, 6‐31+G(d) and 6‐311++G(3df,2pd), and Dunning basis sets, aug‐cc‐pVTZ and aug‐cc‐pVQZ, were used. SH and CS frequency shifts upon water complexation were studied, and a discussion is performed on the expected relation between the CH and CS Raman activities, in view of their usefulness for studies in protein chemistry. Scaling factors for the vibrational frequencies were obtained for all the combination of methods and basis sets, and shown to be completely similar to the ones present in the literature when available. Scaling factors for the M06 method are presented for the first time with these basis sets. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2010
A network selection scheme for multicast applications in wireless network convergence
Authors: Kim Jaecheol , Lee Ji Hoon , Lee Hojin , Kwon Taekyoung , Choi Yanghee 
Published: October 2010

ABSTRACTIn wireless network convergence, each mobile host is expected to have multiple kinds of wireless interfaces. Multicast‐based applications are expected to be widely deployed. In this paper, a new network selection scheme is proposed for a mobile host to select the most appropriate wireless access network to maximize user satisfaction and ISP's profit, simultaneously. We have devised a metric to measure a user's satisfaction and we also developed a ‘normalized network resource’ metric for system profit measure. We have compared our scheme with three other reference schemes, through simulations. Depending on the network deployment situations, our scheme exhibits one‐fifth service disruption time of other reference schemes, while the resource consumption of our scheme is comparable to that of the minimum resource scheme. Overall, the gain of our scheme becomes higher as users move faster and/or the population density increases. Copyright © 2010 John Wiley & Sons, Ltd.
Radioisotope‐induced EDXRF investigation of elemental uptake in cauliflower grown at MSW‐contaminated site
Authors: Gupta D. , Chatterjee J. M. , Ghosh R. , Mitra A. K. , Roy S. , Sarkar M. 
Published: October 2010

AbstractA 109Cd radioisotope‐induced energy dispersive X‐ray fluorescence (EDXRF) study has been performed on samples of cauliflower consisting of the flower, the leaves and the associated root soil. The cauliflowers are collected from farms near the main dumping site of municipal solid waste (MSW) in the city of Kolkata, India, and also from uncontaminated farms about 50 km away from the city. The systematic investigation is primarily aimed at achieving two correlated objectives. Firstly, a unified calibration approach is undertaken for the study tool viz., EDXRF spectrometer, through the use of same instrumental scattering constants for quantification in widely differing matrices like soil and plant. Quality control was done by quantitative reproduction of National Institute of Standards and Technology–Standard Reference Materials (NIST–SRMs). Subsequently, the second objective is to comparatively study elemental uptake in the cauliflower samples from contaminated and uncontaminated farms using the same calibration. This study suggests that the elemental concentrations in the root soils and leaves of the samples vary from farm to farm, whereby the concentrations of Cu, Zn and Pb in root soils of MSW‐contaminated farms are higher by almost an order of magnitude compared to uncontaminated farms. But the most notable feature of this study is the strikingly similar elemental concentrations in the edible flower part of all samples irrespective of the soil type. Plots of the ratio of concentrations of elements in leaf to soil and in flower to leaf, observed from the present EDXRF study suggests that a preferential uptake of elements takes place at different stages. Copyright © 2010 John Wiley & Sons, Ltd.
Genetic Counseling for Early‐onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions
Authors: Butler Rachel , Dwosh Emily , Beattie B. Lynn , Guimond Colleen , Lombera Sofia , Brief Elana , Illes Judy , Sadovnick A. Dessa 
Published: October 2010

AbstractA novel, pathogenic presenilin 1 (PS1) mutation has recently been identified in a large Aboriginal kindred living in dispersed communities throughout British Columbia, Canada. Disseminating genetic information and ensuring that appropriate genetic counseling services are provided to all concerned relatives have posed several unique challenges. These challenges include knowledge exchange and continuity of care in a geographically remote and culturally distinct community. To our knowledge, this is the first time a specific genetic counseling approach has been needed for early‐onset familial Alzheimer disease (EOFAD) in a North American Aboriginal community.
Morphology and Microstructure of As-Synthesized Anodic TiO2 Nanotube Arrays
Authors: Cao Chunbin , Zhang Guoshun , Song Xueping , Sun Zhaoqi 
Published: October 2010

Abstract
The as-grown structure of electrochemically synthesized titania nanotube arrays is investigated by scanning electron microscope (SEM) in combination with transmission electron microscope (TEM) as well as X-ray diffraction (XRD). The analysis reveals a preferred growth direction of the nanotubes relative to the substrate surface and the well control on the nanotube arrays morphology. The crystal structure of the anatase phase is detected and exists in the tube walls without any thermal treatment, which makes it possible to realize the application of as-formed TiO2 nanotubes avoiding the degradation of the nanotube structures when sintering. In addition, a new growth, layered model of the anodic TiO2 nanotubes is presented to obtain further understanding of the growth mechanism.
Products deriving from microbial fermentation are linked to insulinaemic response in pigs fed breads prepared from whole-wheat grain and wheat and rye ingredients
Authors: Theil Peter Kappel , Jørgensen Henry , Serena Anja , Hendrickson Jessica , Bach Knudsen Knud Erik 
Published: October 2010

The effects of wheat and rye breads made from whole-wheat grain (WWG), wheat aleurone flour (WAF) or rye aleurone flour (RAF) on net portal absorption of carbohydrate-derived nutrients (glucose, SCFA and lactate) and apparent insulin secretion were studied in a model experiment with catheterised pigs. The breads were similar in dietary fibre (DF, 120–125 g/kg DM) but differed in arabinoxylans (50–62 g/kg), β-glucans (4–9 g/kg) and content of soluble DF (13–29 g/kg). Six pigs in a repeated 3 × 3 crossover design were fitted with catheters in the portal vein and the mesenteric artery and a portal flow probe. Pigs were fed three meals daily (at 09.00, 14.00 and 19.00 hours), and blood profiles were collected repeatedly from 08.30 until 19.00 hours once weekly. Net portal absorption of glucose was similar among breads and between meals. In contrast, insulin secretion was lowest (P < 0·05) in pigs fed RAF bread (3·9 nmol/h), intermediate in pigs fed WAF bread (5·4 nmol/h) and highest in pigs fed WWG bread (5·9 nmol/h), indicating that RAF bread improved insulin economy. Portal concentrations of propionate, butyrate and valerate were high, intermediate and low (P < 0·05) when pigs were fed RAF, WAF and WWG breads, respectively. Insulin secretion was higher (P < 0·001), and portal absorption of SCFA was lower (P < 0·05) after the first daily meal than after the second daily meal (8·8v. 4·4 nmol/h). A low insulin response was associated with high portal absorption of SCFA. In conclusion, RAF bread was able to improve insulin economy compared to WWG bread.
Food and Nutrition Security at Risk in Later Life: Evidence from the United Kingdom Expenditure & Food Survey
Authors: DEEMING CHRIS 
Published: October 2010

AbstractSecuring adequate food and nutrition is essential for the maintenance of our health and function in society. This article examines the household characteristics associated with food and nutrition security in the United Kingdom population aged 60 years and over. Data are taken from the Expenditure and Food Survey, a continuous cross-sectional survey of household expenditure, food consumption and income. Survey data for 2002–05 provided a total sample of 5,600 households. Household food consumption is evaluated using national Dietary Reference Values recommended by the Department of Health. A multivariate logistic regression model examines the risk of being food and nutrition insecure by individual and household characteristics. The results suggest that certain sections of the older population are significantly more at risk of food insecurity than others: low-income households, the oldest-old, elderly from black and minority ethnic groups, those with a disability and men living alone. Influencing nutrition of elderly people in the home is complex and poses a major challenge to social policy. Coordinated activity at national and local levels will be required to help ensure that some of the most vulnerable members of society achieve healthy balanced diets.
Welfare-to-Work and the Responsiveness of Employment Providers to the Needs of Refugees
Authors: SHUTES ISABEL 
Published: October 2010

AbstractImproving the responsiveness of service providers to the needs of users has been a principal aim of welfare state reform. In the context of employment provision, this article explores the effects of a job outcome-oriented performance system on the responsiveness of providers to the needs of unemployed refugees. These effects concern, first, the type of refugees to whom providers are responsive and, second, the type of employment assistance provided. It is argued that an emphasis on short-term job outcomes may conflict with supporting refugees who are ‘harder to help’, particularly those with English language needs. It may also conflict with supporting refugees to access employment related to their skills and interests by encouraging providers to focus on placing refugees in ‘easy to access’, low-skilled and low-paid jobs. The effects may, therefore, serve to reproduce labour market inequalities experienced by refugees.
A rejoinder to Michael Cox
Authors: Heuser Beatrice 
Published: October 2010

It is a great thrill to find that someone has picked up the gauntlet thrown into the arena at a time when the Cold War seems to many to be nothing but remote history. Here are my brief answers to Michael Cox's gallant repartee:Tito did not ‘defect’ he was expelled from the Cominform by Stalin. Moscow did not ‘stay put’ altogether; Tito's expulsion was supposed to be followed by a putsch by the Stalinist faction within the CP of Yugoslavia, which failed, however. Here, as with the Berlin Blockade and later in condoning aggression in Korea (hardly ‘cautious, circumspect’ policy decisions), Stalin made a great mistake.Western analysts did predict the attack on South Korea. In May 1950 Kennan himself thought Stalin was looking for an area to have a ‘limited war’, and thought Yugoslavia a likely danger area. Mr Kennan's later Memoirs and memory are here, once again, not very reliable.The Communist victory in China and the Soviet explosion of an atomic device, far from being of little concern to the West, caused Truman to ask for NSC-68 to be written.The economically weak USSR was far from inferior to the West in manpower, as Dr Cox rightly notes, and it should be remembered that the Red Army had held its own against the formidable Wehrmacht for quite a while. The massive rearmament of the satellites of the USSR only started in 1948. Matthew Evangelista's article only deals with the period up to 1948, and its findings can not be applied to the 1949–1953 period. Satellite rearmament took off in 1950, peaking in 1952. By 1952 Rumania, Hungary and Bulgaria alone had as many forces (including small naval and air forces) as the 800,000 Western troops available on the Central Front in 1948.
Information needs of health technology assessment units and agencies in Spain
Authors: Galnares-Cordero Lorea , Gutiérrez-Ibarluzea Iñaki 
Published: October 2010

Objectives: The aim of this study was to analyze the information needs of Spanish health technology assessment (HTA) agencies and units to facilitate access to the resources they require to substantiate their reports.Methods: A questionnaire was designed and distributed among HTA bodies to ascertain the actual situation of subscriptions to information resources and what information specialists from these bodies considered would be the ideal subscription situation. Their information needs were then studied, and the resources that best met these needs were put forward. Following this definition, a subscriptions policy was adopted with suppliers and publishers.Results: The survey showed that HTA bodies share a minimum of core subscriptions that includes open sources (MEDLINE, DARE) and sources that the government subscribes to for the health community (ISI Web of Science, Cochrane Library Plus). There was no common approach to determining which databases to subscribe to (UpToDate, EMBASE, Ovid EBMR, CINAHL, or ECRI). After identifying the information needs, a list of resources was proposed that would best cover these needs and, of these, subscription to the following was proposed: Scopus, Ovid EBMR, Clinical Evidence, DynaMed, ECRI, and Hayes.Conclusions: There are differences in the way that HTA agencies and units access the different resources of biomedical information. Combined subscription to several resources for documentation services was suggested as a way of resolving these differences.
Information on ethical issues in health technology assessment: How and where to find them
Authors: Droste Sigrid , Dintsios Charalabos-Markos , Gerber Andreas 
Published: October 2010

Background: Comprehensive health technology assessments (HTAs) include thorough reflections on ethical issues associated with health technologies, their use, and value-based decisions in the assessment process. As methods of information retrieval for effectiveness assessments are not applicable to information retrieval on ethical issues, a specific methodological approach is necessary.Objectives: In the absence of existing adapted methods, our objective was to develop a methodological approach for the systematic retrieval of information on ethical issues related to health technologies.Method and Results: A literature search was conducted to verify the non-existence of published comprehensive methodological approaches for the information retrieval on ethical issues for HTAs, and resulted in no hits. We, therefore, developed a step-by-step workflow following the workflow of information retrieval for effectiveness assessments: Step 1: Translation of the search question using the PICO scheme and additional components. Step 2: Concept building by modeling and linking search components. Step 3: Identification of synonyms in all relevant languages. Step 4: Selection of relevant information sources. Step 5: Design of search strategies for bibliographic databases. Step 6: Execution of search strategies and information seeking, including hand-searching. Step 7: Saving of retrieval results and standardized reporting of the process and results. Step 8: Final quality check and calculation of precision and recall.Conclusions: Systematic searching for information on ethical issues related to health technologies can be performed following the common retrieval workflow for effectiveness assessments, but should be performed separately applying adapted procedures and search terms on ethical issues relevant to the research question.
Centre for Reviews and Dissemination databases: Value, content, and developments
Authors: Booth Alison M. , Wright Kath E. , Outhwaite Helen 
Published: October 2010

Background: The Centre for Reviews and Dissemination (CRD) funded through the United Kingdom National Institute for Health Research undertakes systematic reviews evaluating the research evidence on health and public health questions of national and international importance. CRD is involved in methods research and produces internationally accepted guidelines for undertaking systematic reviews. A core product of the Centre are the CRD databases; a key resource for health professionals, policy makers, and researchers around the world. Research evidence evaluating the effects and cost-effectiveness of healthcare interventions is growing year on year, and can be difficult and time consuming to identify and appraise. The databases assist decision makers by systematically identifying and critically describing systematic reviews and economic evaluations, appraising their quality and highlighting their relative strengths and weaknesses; and providing a comprehensive listing of ongoing and published health technology assessments.Methods and Results: This article briefly outlines the processes behind each of the three databases, gives details of the records, the information they contain and the value added by CRD. An overview of the new public interface for the CRD databases to be launched later this year is given. Improvements and innovations to supplement existing functions are listed, including enhanced and new search options, the addition of quick links to relevant material from within individual records, an integrated PubMed search and the ability to select personal preferences.Conclusions: CRD's databases provide free access to an important knowledge base and are used widely to underpin evidence informed healthcare decisions in the United Kingdom and internationally.
Classification of evidence in decision-analytic models of cost-effectiveness: A content analysis of published reports
Authors: Paisley Suzy 
Published: October 2010

Objectives: The aim of this study was to assess systematically the scope of evidence and purposes for which evidence is used in decision-analytic models of cost-effectiveness and to assess the implications for search methods.Methods: A content analysis of published reports of models was undertaken. Details of cited sources were extracted and categorized according to three dimensions; type of information provided by the evidence, type of source from which the evidence was drawn and type of modeling activity supported by the evidence. The analysis was used to generate a classification of evidence. Relationships within and between the categories within the classification were sought and the implications for searching considered.Results: The classification generated fourteen types of information, seven types of sources of evidence and five modeling activities supported by evidence. A broad range of evidence was identified drawn from a diverse range of sources including both research-based and non–research-based sources. The use of evidence was not restricted to the population of model parameters but was used to inform the development of the modeling framework and to justify the analytical and methodological approach.Conclusions: Decision-analytic models use evidence to support all aspects of model development. The classification of evidence defines in depth the role of evidence in modeling. It can be used to inform the systematic identification of evidence.
Longitudinal strain and strain rate by tissue Doppler are more sensitive indices than fractional shortening for assessing the reduced myocardial function in asphyxiated neonates
Authors: Nestaas Eirik , Støylen Asbjørn , Brunvand Leif , Fugelseth Drude 
Published: October 2010

AbstractThe function of the heart was studied in 20 asphyxiated term neonates by measuring the longitudinal peak systolic strain and peak systolic strain rate by tissue Doppler in 18 segments of the heart on days 1, 2, and 3 of life. The fractional shortening was assessed at each examination as well. Measurements were compared against measurements in 48 healthy term neonates examined by the same protocol. The function of the heart was lower in the asphyxiated neonates – peak systolic strain (mean (95% confidence interval) −19.4% (−20.4, −18.5), peak systolic strain rate −1.65 (−1.74, −1.56) per second) than in the healthy term neonates (peak systolic strain −21.7% (−22.3, −21.0), peak systolic strain rate −1.78 (−1.84, −1.74) per second; p < 0.001). Fractional shortening was similar in the asphyxiated (29.2% (26.8, 31.5)) and healthy term neonates (29.0% (27.9, 30.1); p = 0.874). The peak systolic strain differed significantly between the asphyxiated and healthy term neonates for the left basal and right basal groups of segments (p < 0.05) but not for the left apical, right apical, septum apical, or septum basal groups of segments. The peak systolic strain rate differed significantly only for the septum apical group of segments. The differences were largest on the second day of life. Measurements were similar in asphyxiated neonates with elevated and normal cardiac troponin T levels. The peak systolic strain and strain rate were in this study more sensitive indices than fractional shortening for assessing the reduced myocardial function in asphyxiated term neonates.