bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Public Private Partnerships in Strengthening Faith-Based Health Systems in Kisii County, Kenya
Authors: Ringera William , Tenambergen Wanja , Oluoch Musa 
Published: February 2025

Public-Private Partnerships (PPPs) are important in enhancement of efficiency and effectiveness in different agencies. PPPs is a concept that has been borrowed and applied in various sectors. It is noted that within governments, Health Ministries’ focus on the public sector often disregard the frequently much larger private finance and private provision of healthcare. This study examined the effects of PPPs in material support, leadership/management, and human resources for health (HRH) on strengthening of health systems in faith-based organization (FBO) health services in Kisii County, Kenya. A cross-sectional descriptive study was conducted targeting 78 FBO facilities’ officials from Tabaka, Christianmarian and Nyanchwa; and officials from the Ministry of Health. Data was collected using structured questionnaires and interview schedules, and analysed using SPSS Version 20 and Ms. Excel. The study found that PPP on leadership and management, material support, HRH and provision of guidelines for the implementation of the PPP were significantly associated with strengthening of FBO health systems at p<0.05.The study conclude that PPPs targeting material support, leadership and management, provision of guidelines for PPP process, and HRH improved provision of public health services in FBO facilities in Kisii County. Therefore, the PPP is yielding fruits in the Government’s effort to strengthen delivery of public health services, particularly in areas of HIV/AIDS and maternal, neonatal and child health-MNCH, in Kisii County. From the viewpoint of Kisii County Government, FBO facilities are able to effectively complement the work of government in public health services and should be supported through the PPPs.
Democratization of Student Leaders’ Elections and its Effect on Students’ Discipline in Public Secondary Schools in Meru County, Kenya
Authors: M’muyuri Misheck Mutuma , Kibaara Tarsila , Severina Mwirichia 
Published: February 2025

Democratization of student leaders’ appointment is one of the approaches designed to enhance student discipline. However, the link between this approach and students’ discipline has been unclear considering the rise in misconduct among students. This study sought to determine the effect of involving students in electing their leaders on students' discipline in public secondary schools in Meru County. The Bandura’s social learning theory of 1977 was critical in guiding this study. The study applied a descriptive survey research design to select ten principals, 196 deputy principals, and 384 student leaders. Schools were stratified into categories, before a systematic sampling technique was applied in each stratum. Both the principals and the deputy principals were purposively selected, while simple random sampling was used in selecting students’ leaders. Questionnaires, interviews, and document analysis were utilized in collecting data, while factor analysis, frequencies, percentages and means were computed with the help of SPSS. Ordinal logistical regression analysis was used to test the hypothesis, while the thematic technique was used to analyze the qualitative data. Cases of indiscipline were prevalent in most public secondary schools in Meru County. The study found out that only 52% of schools allowed students to elect their leaders, while 48% had students’ leaders appointed by teachers. Many schools lacked elaborate electoral processes and a profound orientation program for students’ leaders. Students' involvement in electing their leaders was statistically significant in affecting secondary schools' discipline. The study recommended the Ministry of Education to liaise with principals of secondary schools in streamlining the electoral processes, develop student leadership electoral policy, and devise holistic involvement mechanisms to ensure free and fair elections of students’ leaders. Further, the study recommended that principals should educate students on electoral processes and train the elected leaders on effective leadership.
Societal Factors and the Discipline of Pastors' Children in the Context of Church Mission in Tigania West Sub-county, Meru County, Kenya
Authors: Mathiu Ntarangwi Lichoro , Njoroge John Ngige , Gitonga Monica 
Published: February 2025

Discipline, whether of children or adults, has a lot of impact in any society. The peace, unity, and prosperity of any society are dependent on the discipline of its people. As important as it is, discipline is at times affected to the detriment of society by some factors. Globally, continentally, nationally, and locally, there have been reported issues on the discipline of pastors' children. The discipline of pastors' children affects the performance of the pastor. Therefore, this study sought to establish the effect of societal factors on the discipline of pastors' children in the context of church mission in Tigania West Sub-County, Meru County, Kenya. The researcher used a qualitative research approach and phenomenological research design in this study. The target population was 431 people. Purposive sampling was used, and twenty-five (25) respondents were engaged in this study: 10 pastors, 10 pastor's children, and 5 church elders. Thematic narrative analysis of data was adopted in this study. The study established that pastors' children always feel pressured to be right hence making them stressed. Prolonged stress leads to depression resulting in more indiscipline cases like immorality and drug and substance abuse. The study recommended that church managers should engage counselling professionals who would occasionally provide one-on-one counseling sessions to the pastors' children and always keep in touch with them for their mental and physical wellbeing. Further research should be done to establish the influence pastors’ children have on each other's behaviour
OK392 (‘Mamont Noir’) a Red-Pulped Bunch Grape with Potential for Upper South Vineyards
Authors: Stafne Eric T. , Carroll Becky L. , Williams Haley N. , Coker Christine E.H. , Sampson Blair J. 
Published: February 2025

The grape industry is expanding acreage production of wine, juice, and other value-added products throughout the United States. Recent estimates show the grape and wine industries in states surrounding Mississippi have significant economic impact. To prepare for a potential expansion of the grape industry in Mississippi, underappreciated cultivars and breeding selections are being grown, harvested, and processed to determine suitability. A selection from Oklahoma, OK392, was grown for several years at the Mississippi State University (MSU) Beaumont Horticultural Unit as well as the Oklahoma State University Cimarron Valley Experiment Station. OK392 compared favorably to other hybrid bunch grapes in many measured categories; however, it did have higher loads of Pierce’s disease (PD) (Xylella fastidiosa) in Mississippi. Even with the higher detected PD, vines are still surviving in South Mississippi and producing grapes. Wine was also made from fruit collected and it has promise in blending and as a teinturier to provide deep red color for other grapes. Overall, OK392 has potential for upper South vineyards and may be useful in grape breeding programs as well, and we propose the name ‘Mamont Noir’ for future use.
Groundwater depletion and its implications for rural livelihoods in Zimbabwe
Authors: MADYA FELIX , CHIVANDIRE CHRISTINE , NDEMO NYASHA , MUSARA ENOCK 
Published: February 2025

This study critically explores the adverse impacts of groundwater depletion on the livelihoods of people in the rural areas of Zimbabwe. Water is one of the most important aspects of rural livelihoods in Zimbabwe as most of these livelihoods are centred on agriculture. We proffer the argument that, owing to the adverse effects of climate change, water scarcity has become more common in most areas and its effects are being felt and adversely experienced among the livelihoods in various rural settings where the supply of clean water has always been a major problem. This study is based on primary and secondary data with primary data collected through field surveys. Many rural residents were interviewed through questionnaires on how the depletion of water is a major crisis and threat to their livelihoods. Secondary data sources including articles, journals, books, report documents and case studies from various recognised publications. The data was analysed using qualitative techniques and presented using thematic analysis. The findings claim that the depletion of groundwater is a major threat to the livelihoods of the rural population. The reduction of groundwater has led to the abandonment of agricultural livelihoods by the people in Zimbabwe’s rural areas. The depletion of groundwater is a result of continued use with failure to recharge. Due to the chain of reliance on agriculture and crop cultivation in rural areas, most livelihoods are affected by the groundwater crisis. There are no more or less surplus products to trade for other goods or income and those relying on selling labour continue to suffer more and migrate to urban areas for better opportunities thus having an impact on population distribution in rural areas. Lack of other means of acquiring water and outbreak of diseases have a huge influence also on livelihoods. The study concludes that rural livelihoods need to be rethought and ways must be sought of ensuring robust and sustainable rural communities. It is proposed that smart technologies should be used for rural livelihoods.
La littératie informationnelle au primaire : étude de cas de lecteur·rices internautes de 6e année
Authors: Pleau Joannie 
Published: February 2025

Le présent article décrit une étude de cas multiples qui s’est penchée sur l’interaction des compétences de navigation, d’évaluation et d’intégration au sein d’un processus menant à la compréhension d’informations consultées en ligne, et ce, lors de la réalisation d’une tâche de littératie informationnelle par des lecteur·rices internautes de 6e année. L’étude combine l’entretien direct, la verbalisation de la pensée, l’entretien libre de verbalisation de la compréhension et l’entretien rétrospectif semi-dirigé. Elle permet l’induction d’une mobilisation autorégulée des compétences, en plus de permettre, au départ des convergences et des divergences observées entre les cas, la formulation d’une hypothèse de profils de lecteur·rices internautes.
Climate Justice
Authors: Sunstein Cass R. 
Published: February 2025

The social cost of carbon: The most important number you've never heard of—and what it means.
If you're injuring someone, you should stop—and pay for the damage you've caused. Why, this book asks, does this simple proposition, generally accepted, not apply to climate change? In Climate Justice, a bracing challenge to status quo thinking on the ethics of climate change, renowned author and legal scholar Cass Sunstein clearly frames what's at stake and lays out the moral imperative: When it comes to climate change, everyone must be counted equally, regardless of when they live or where they live—which means that wealthy nations, which have disproportionately benefited from greenhouse gas emissions, are obliged to help future generations and people in poor nations that are particularly vulnerable.
Invoking principles of corrective justice and distributive justice, Sunstein argues that rich countries should pay for the harms they have caused and that all of us are obliged to take steps to protect future generations from serious climate-related damage. He shows how “choice engines,” informed by artificial intelligence, can enable people to save money and to reduce the harms they produce. The book casts new light on the “social cost of carbon,”—the most important number in climate change debates—and explains how intergenerational neutrality and international neutrality can help all nations, crucially the United States and China, do what must be done.
Seasonal Impacts of Spring Shed Management on Water Quality: Enhancing Water Security in Lathao Village of Namsai District, Arunachal Pradesh, India
Authors: Guru Nibedita , Hazarika Prosanta , Gosavi Vaibhav Ecknath 
Published: February 2025

The seasonal impacts of spring shed management on water quality play a crucial role in ensuring long-term water security for rural communities. The primary source of freshwater for the local population is the spring water. That was evident in a study conducted for rejuvenation of 5 dying springs of Lathao village Namsai district, Arunachal Pradesh, India during 2020 to 2024. During this period number of interventions such as conical ponds (12), nallah bunds(10), and vegetative measures were implemented for spring shed management. A noticeable result has been observed due to the impact of seasonal variations, together with climate change and land use pattern on water quality and quantity.
This study investigates key physico-chemical parameters of spring water such as pH, Temperature, TDS, and electrical conductivity to evaluate the effectiveness of spring shed management before and after the interventions on the across different seasons in a cluster of 5 springs.The samples for the chemical analyses were collected at an interval of six months.
Primary results depicted significant improvement in water quality due to spring shed management, particularly during the summer season when water scarcity and contamination risks are high. The obtained results were within the permissible limits of World Health Organization's (WHO) with exception of pH. The pH concentration was below the permissible limit with a mean value of 5.76±0.08 (monsoon), 5.70±0.09 (PrM), and 5.85±0.07 (PoM) in all seasons were mildly acidic. After intervention work, the concentration values for all parameters are increasing. However, no significant inference can be drawn from the chemical analyses of the samples and could be ascertained later with time after having sufficient data. However there has been a notable drop in the levels of Total Hardness (approx 50%) and Calcium concentration (approx 70%) after intervention.
The findings underscore the importance of community-driven and sustainable approaches for managing natural water resources, ensuring that rural populations have reliable access to clean water year-round.
Study by Molecular Docking of the Interactions between Dihydroorotate Dehydrogenase and a Series of Inhibitors of Pyrrole Derivatives for the treatment of Malaria
Authors: Adama Niaré , Alex Attia Yapo John , Bernard Djako Akassa Marius , Marius Kambiré Sobamfou , Stéphane Dembélé Georges , Moise Kouadio Assandé , Guy-Richard Koné Mamadou , Fagnidi Yves Kily Hervé , Doh Soro 
Published: February 2025

Malaria, although a curable disease, continues to be the most important infectious disease in terms of incidence and mortality worldwide. It is a potentially fatal disease caused by parasites transmitted to people through the bites of infected female Anopheles mosquitoes. This disease affects more than 216 million people and kills a million, mainly children and pregnant women. Anti-malaria therapy finds itself confronted with drug-resistant strains, hence the urgency of finding new targets and new anti-infectious agents. Dihydroorotate dehydrogenase (DHODH) is an essential enzyme for the design of new antimalarial drugs. Using a Computer Aided Molecular Design (CAMD) reaction approach, a series of 17 molecules from the pyrrole family, inhibitors of (DHODH) was designed within the protein (PDB code: 6VTN). These molecules with known \(IC_{50}\) were selected to build an RQSAR model presenting a linear correlation between the Gibbs energy (∆∆G), the complexes formed and the experimental inhibition potential (\(pIC_{50}^{exp}\)) : \(pIC_{50}^{exp}\) = - 0.2909 × ∆∆G + 7.7715 ; R2 = 0,97. we subsequently carried out a study on the catalytic residues (interaction by residue) in order to exploit the different interactions (enzyme: inhibitor).The predictive power of the QSAR model was validated by the generation of 3D-QSAR pharmacophores (PH4): \(pIC_{50}^{exp}\) = 0.9939 x \(pIC_{50}^{est}\) + 0.0421 ; R2 = 0.92.
Clinical, Hematological and Biochemical Profile of Dengue Syndromes in Children
Authors: Khatun Habiba , Kabir Farzana , Sultana Afroza , Rahman Shaidur , Rahman Toshiba , Islam Md. Atiqul , Khan Tasnuva 
Published: February 2025

Background: Dengue is a viral disease transmitted by mosquito bites with arising global incidence, more commonly afflicting children in endemic countries such as Bangladesh. Among the severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), there are hematological and biochemical complications. This study aims to evaluate the clinical, hematological and biochemical predictor of severity in pediatric dengue syndromes with the intention of improved clinical management.
Methods: A cross sectional analytical study conducted at the Department of Pediatrics, Dhaka Medical College Hospital from April 2019 to March 2020. A total of 350 hospitalized children aged 1 month to 12 years with confirmed dengue positive were included in this study. Descriptive statistics were performed on clinical symptoms, hematological parameters and biochemical markers in order to test corresponding standard significance tests.
Results: The most common symptoms were high grade fever (93.14%); vomiting (78.86%); abdominal pain (43.14%). 14.85% of DSS cases had severe thrombocytopenia (<20,000 cells/mm³). 13.86 % of DSS cases had elevated hematocrit (>45 %). In severe cases there were biochemical derangements including high SGPT (59.76% in DHF) and prolonged PT (>16 seconds). In DSS 35.15% were hypoproalbuminemic (< 3.0 gm/dl). Expanded dengue syndrome was characterized by hypocalcemia (62.5%) and elevated serum creatinine (25%).
Conclusion: The clinical and laboratory markers highlighted here for early detection of severe dengue in children will help in early intervention to reduce morbidity and mortality.
Association of New-Onset Seizures With SARS-CoV-2 Vaccines
Authors: Rafati Ali , Jameie Melika , Amanollahi Mobina , Pasebani Yeganeh , Jameie Mana , Kabiri Ali , Montazeri Namin Sara , Sakhaei Delaram , Feizollahi Fateme , Pasebani Mohammad Yazdan , Mohebbi Hossein , Ilkhani Saba , Azadi Mohammadreza , Rahimlou Mehran , Kwon Churl-Su 
Published: April 2024

ImportanceSeizures have been reported as an adverse effect of the SARS-CoV-2 vaccine. However, no study has answered the question of whether there is any association between seizures in the general population and COVID-19 vaccination.ObjectiveTo evaluate the seizure incidence among SARS-CoV-2 vaccine recipients compared with those who received a placebo.Data SourcesA systematic search of MEDLINE (via PubMed), Web of Science, Scopus, Cochrane Library, Google Scholar, review publications, editorials, letters to editors, and conference papers, along with the references of the included studies from December 2019 to July 7, 2023.Study SelectionRandomized clinical trials (RCTs) reporting seizure incidence with SARS-CoV-2 vaccination were included.Data Extraction and SynthesisThis study is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework and used the Mantel-Haenszel method with random- and common-effect models. The risk of bias of the studies was assessed using the Cochrane assessment tool for RCTs.Main Outcomes and MeasuresThe outcome of interest was new-onset seizure incidence proportion compared among (1) SARS-CoV-2 vaccine recipients and (2) placebo recipients.ResultsSix RCTs were included in the study. Results of the pooled analysis comparing the incidence of new-onset seizure between the 63 521 vaccine and 54 919 placebo recipients in the 28-day follow-up after vaccine/placebo injection showed no statistically significant difference between the 2 groups (9 events [0.014%] in vaccine and 1 event [0.002%] in placebo recipients; odds ratio [OR], 2.70; 95% CI, 0.76-9.57; P = .12; I2 = 0%, τ2 = 0, Cochran Q P = .74). Likewise, in the entire blinded-phase period after injection, with a median of more than 43 days, no significant difference was identified between the vaccine and placebo groups regarding incident new-onset seizure (13/43 724 events [0.03%] in vaccine and 5/40 612 [0.012%] in placebo recipients; OR, 2.31; 95% CI, 0.86-6.23, P = .10, I2 = 0%, τ2 = 0, Cochran Q P = .95).Conclusions and RelevanceAccording to this systematic review and meta-analysis, there was no statistically significant difference in the risk of new-onset seizure incidence between vaccinated individuals and placebo recipients.
Comparison of failure modes and effects analyses and time for brachytherapy ring and tandem applicator digitization between manual and solid applicator source placement methods
Authors: Holtman Adia L. , DiCostanzo Dominic J. , Zimmerman Charles A. , Graeper Gavin , Woollard Jeffrey , Christ Daniel F. , Cetnar Ashley J. 
Published: April 2024

AbstractPurposeRing and tandem (R&T) applicator digitization is currently performed at our institution by manually defining the extent of the applicators. Digitization can also be achieved using solid applicators: predefined, 3D models with geometric constraints. This study compares R&T digitization using manual and solid applicator methods through Failure Modes and Effects Analyses (FMEAs) and comparative time studies. We aim to assess the suitability of solid applicator method implementation for R&T casesMethodsSix qualified medical physicists (QMPs) and two medical physics residents scored potential modes of failure of manual digitization in an FMEA as recommended by TG‐100. Occurrence, severity, and detectability (OSD) values were averaged across respondents and then multiplied to form combined Risk Priority Numbers (RPNs) for analysis. Participants were trained to perform treatment planning using a developed solid applicator protocol and asked to score a second FMEA on the distinct process steps from the manual method. For both methods, participant digitization was timed. FMEA and time data were analyzed across methods and participant samplesResultsQMPs rated the RPNs of the current, manual method of digitization statistically lower than residents did. When comparing the unique FMEA steps between the two digitization methods, QMP respondents found no significant difference in RPN means. Residents, however, rated the solid applicator method as higher risk. Further, after the solid applicator method was performed twice by participants, the time to digitize plans was not significantly different from manual digitizationConclusionsThis study indicates the non‐inferiority of the solid applicator method to manual digitization in terms of risk, according to QMPs, and time, across all participants. Differences were found in FMEA evaluation and solid applicator technique adoption based on years of brachytherapy experience. Further practice with the solid applicator protocol is recommended because familiarity is expected to lower FMEA occurrence ratings and further reduce digitization times.