bluuebunny/crossref_metadata_2025_split huggingface dataset:
A user perspective on youth mental health services: Increasing help‐seeking behaviour requires addressing service preferences and attitudinal barriers
Authors: Wittevrongel Eline , Kessels Roselinde , Everaert Geert , Vrijens May , Danckaerts Marina , van Winkel Ruud 
Published: June 2024

AbstractAimAlthough the incidence of mental health problems is highest in young people, the majority do not seek help. Reducing the discrepancy between need for care and access to services requires an understanding of the user perspective, which is largely lacking. This study aimed to examine preferences for mental health service attributes and their relative importance among young people, as well as the potential impact on actual help‐seeking intentions.MethodsYouth aged 16–24 years (N = 258) participated in a discrete choice experiment. In addition to choosing which service would suit their needs most out of two service options in nine choice sets, participants were asked whether they would consult the chosen service in the case of mental health problems. Demographic information was also collected, as well as their current mental health status, experience with and perceived barriers to care. Panel mixed logit models were estimated.ResultsYoung people's preferences were mostly driven by the attribute ‘format’, with a preference for individual rather than group therapy. Other attributes, in order of importance, were ‘wait times’ (short), ‘cost’ (low), ‘healthcare professionals' expertise’ (particular experience with working with youth aged 12 to 25 years), and ‘location’ (house in a city). However, a majority of young people would not consult the service they had indicated, mainly due to attitudinal barriers such as wanting to deal with problems on their own (self‐reliance).ConclusionsAddressing psychological barriers to access care should be a priority in mental health policies. Furthermore, entry point services, in particular, should be able to provide the option of individual treatment.
Arts Practice as the Daily Extraordinary: A Philosophy of Inclusivity
Authors: Matthews Miranda 
Published: June 2024

AbstractTo conceive a philosophy of art education that is removed from actual practice would belie the extraordinary experience of developing and making practice. In this article, I propose to explore the philosophical implications of art practice being an experience of the ‘daily extraordinary.’ A view of practice as being at once stretching and comfortable, takes the artist and viewer's responses to the strangeness of the everyday: the delightful, the shocking, or even the miraculous, in what appear to be simple and mundane experiences. If we perceive learning in the arts as a pursuit of ideas, affect and expression that occurs in regular practice, there is an inclusivity that renders both learning in the arts and philosophy of art education accessible to everyone. In this article I will refer to the Goldsmiths Centre for Arts and Learning's research programme of 2022–2023, in which events and connected teaching activities practised being All For the Arts. With visiting speakers, museums and galleries and postgraduate students, CAL researched how the vitality and challenge of art practice, which includes the individualities and expression of persons and histories made ordinary and invisible, could bring the value of learning in the arts to the fore. Including reflections from contributors such as John Baldacchino, A Particular Reality, Carol Wild, Danny Braverman, Raphael Vella, Kevin Tavin and Andrea Kárpáti, we explored inclusivity in art practice from the daily extraordinary of each speaker's developments in educational research. Also, in the company of representatives from arts organisations such as Entelechy Arts, Autograph ABP, Whitechapel Gallery, Young V&A and Bow Arts, we considered the amazing and essential factors of inclusivity in the arts – that could be encountered on a daily basis. I will gather meeting points here among this incredible range of contributors.
MiR‐26a and miR‐191 are upregulated while PLAG1 and HIF2 are downregulated in pleomorphic adenomas of the salivary glands compared to Warthin tumors
Authors: Carkic Jelena , Nikolic Nadja , Sango Violeta , Riberti Nicole , Anicic Boban , Milasin Jelena 
Published: June 2024

AbstractBackgroundSalivary gland tumors (SGTs) are a heterogenous group of pathologies, which still represents a challenge regarding differential diagnosis and therapy. Although histological findings govern SGTs management, detection of molecular alterations is emerging as an effective additional tool. The aim of this study was to analyze the relative expression levels of three micro RNAs (miR‐26a, miR‐26b, and miR‐191), and three pro‐oncogenic molecular markers (PLAG1, MTDH, and HIF2) in SGTs and normal salivary gland (NSG) tissues and evaluate them as potential differential diagnosis markers.MethodsThis cross‐sectional study included 58 patients with SGTs (23 pleomorphic adenomas, 27 Warthin tumors, and 8 malignant SGTs) and 10 controls (normal salivary gland tissues). Relative gene expression levels of all investigated molecules were determined by reverse transcriptase‐real‐time polymerase chain reaction.ResultsAll three micro RNAs exhibited highest expression levels in benign SGTs, whereas miR‐26a And miR‐191 were significantly more expressed in PAs compared to WTs (p = 0.045 and p = 0.029, respectively). PLAG1 And HIF2 were both overexpressed in WTs compared to PAs (p = 0.048 and p = 0.053, respectively). Bioinformatic analysis suggested that all investigated micro RNAs function as negative regulators of MTDH.ConclusionThe results of this study suggest that all three micro RNAs have a considerable negative impact on MTDH oncogene expression in malignant tumors, while the differences between levels of miR‐26a, miR‐191, PLAG1, and HIF2 in PA and WT represent possible differential diagnosis markers.
Capturing the contradictory beauty of Mexico City in The Romanoffs
Authors: Lozano‐Alonso Angélica 
Published: June 2024

AbstractThrough a cultural studies approach to identity and spatial studies, this article considers how the spaces and communities of “Panorama” of The Romanoffs series paint a fuller visual portrait of contemporary Mexico City then first meets the eye. For every scene that celebrates the wealth of Mexico City and tourist landmarks, there is a parallel one that shows Mexico's poverty or working‐class communities. “Panorama” is a love story to Mexico City that showcases the many identities contained in the multifaceted capital, exposes injustice, and ultimately aligns itself with those who are disenfranchised.
Long‐term care and myopia: Optimal linear subsidies for private insurance
Authors: Jasaityte Rosita , Klimaviciute Justina 
Published: June 2024

AbstractThis paper studies optimal linear policy directed at private long‐term care insurance in the context where individuals are myopic, that is, underestimate their dependency risk. Without government intervention, myopic individuals underinsure, while the first‐best optimum requires full insurance. To decentralize the first‐best, one needs personalized linear subsidies on private insurance premiums combined with personalized lump‐sum taxes to finance these subsidies and redistribute resources among individuals. In the second‐best setting where only uniform instruments can be used, the determination of the optimal insurance subsidy rate includes three main considerations: standard efficiency concern, correction for myopia, and redistributive concerns. While the correction for myopia pushes for a higher subsidy rate, the analysis of the redistributive concerns is far less straightforward. Overall, the redistributive concerns depend on three main factors: whether wealthier individuals are less myopic, how the probability of dependency varies with wealth and what is the type of absolute risk aversion exhibited by individual preferences.
Nationwide synthetic human mobility dataset construction from limited travel surveys and open data
Authors: Kashiyama Takehiro , Pang Yanbo , Shibuya Yuya , Yabe Takahiro , Sekimoto Yoshihide 
Published: June 2024

AbstractIn recent years, the explosion of extensive geolocated datasets related to human mobility has presented an opportunity to unravel the mechanism behind daily mobility patterns on an individual and population level; this analysis is essential for solving social matters, such as traffic forecasting, disease spreading, urban planning, and pollution. However, the release of such data is limited owing to the privacy concerns of users from whom data were collected. To overcome this challenge, an innovative approach has been introduced for generating synthetic human mobility, termed as the “Pseudo‐PFLOW” dataset. Our approach leverages open statistical data and a limited travel survey to create a comprehensive synthetic representation of human mobility. The Pseudo‐PFLOW generator comprises three agent models that follow seven fundamental daily activities and captures the spatiotemporal pattern in daily travel behaviors of individuals. The Pseudo‐PFLOW dataset covers the entire population in Japan, approximately 130 million people across 47 prefectures, and has been compared with the existing ground truth dataset. Our generated dataset successfully reconstructs key statistical properties, including hourly population distribution, trip volume, and trip coverage, with coefficient of determination values ranging from 0.5 to 0.98. This innovative approach enables researchers and policymakers to access valuable mobility data while addressing privacy concerns, offering new opportunities for informed decision‐making and analysis.
bZIP60 and Bax inhibitor 1 contribute IRE1‐dependent and independent roles to potexvirus infection
Authors: Adhikari Binita , Gayral Mathieu , Herath Venura , Bedsole Caleb Oliver , Kumar Sandeep , Ball Haden , Atallah Osama , Shaw Brian , Pajerowska‐Mukhtar Karolina M. , Verchot Jeanmarie 
Published: June 2024

Summary

IRE1, BI‐1, and bZIP60 monitor compatible plant–potexvirus interactions though recognition of the viral TGB3 protein. This study was undertaken to elucidate the roles of three IRE1 isoforms, the bZIP60U and bZIP60S, and BI‐1 roles in genetic reprogramming of cells during potexvirus infection.

Experiments were performed using Arabidopsis thaliana knockout lines and Plantago asiatica mosaic virus infectious clone tagged with the green fluorescent protein gene (PlAMV‐GFP).

There were more PlAMV‐GFP infection foci in ire1a/b, ire1c, bzip60, and bi‐1 knockout than wild‐type (WT) plants. Cell‐to‐cell movement and systemic RNA levels were greater bzip60 and bi‐1 than in WT plants. Overall, these data indicate an increased susceptibility to virus infection. Transgenic overexpression of AtIRE1b or StbZIP60 in ire1a/b or bzip60 mutant background reduced virus infection foci, while StbZIP60 expression influences virus movement. Transgenic overexpression of StbZIP60 also confers endoplasmic reticulum (ER) stress resistance following tunicamycin treatment. We also show bZIP60U and TGB3 interact at the ER.

This is the first demonstration of a potato bZIP transcription factor complementing genetic defects in Arabidopsis. Evidence indicates that the three IRE1 isoforms regulate the initial stages of virus replication and gene expression, while bZIP60 and BI‐1 contribute separately to virus cell‐to‐cell and systemic movement.
Domestication of rice may have changed its arbuscular mycorrhizal properties by modifying phosphorus nutrition‐related traits and decreasing symbiotic compatibility
Authors: Li Yingwei , Chen Hanwen , Gu Ling , Wu Jingwen , Zheng Xiutan , Fan Zhilan , Pan Dajian , Li Jin‐tian , Shu Wensheng , Rosendahl Søren , Wang Yutao 
Published: June 2024

Summary

Modern cultivated rice (Oryza sativa) typically experiences limited growth benefits from arbuscular mycorrhizal (AM) symbiosis. This could be due to the long‐term domestication of rice under favorable phosphorus conditions. However, there is limited understanding of whether and how the rice domestication has modified AM properties.

This study compared AM properties between a collection of wild (Oryza rufipogon) and domesticated rice genotypes and investigated the mechanisms underlying their differences by analyzing physiological, genomic, transcriptomic, and metabolomic traits critical for AM symbiosis.

The results revealed significantly lower mycorrhizal growth responses and colonization intensity in domesticated rice compared to wild rice, and this change of AM properties may be associated with the domestication modifications of plant phosphorus utilization efficiency at physiological and genomic levels. Domestication also resulted in a decrease in the activity of the mycorrhizal phosphorus acquisition pathway, which may be attributed to reduced mycorrhizal compatibility of rice roots by enhancing defense responses like root lignification and reducing carbon supply to AM fungi.

In conclusion, rice domestication may have changed its AM properties by modifying P nutrition‐related traits and reducing symbiotic compatibility. This study offers new insights for improving AM properties in future rice breeding programs to enhance sustainable agricultural production.
The subject of literature, the subject of philosophy: Plato, Wittgenstein, and Kierkegaard's reading of Abraham
Authors: Dauber Kenneth 
Published: June 2024

AbstractThough Plato, famously, had Socrates ban the poets from his republic while Wittgenstein seems to aspire to a style of philosophical writing that approaches the literary, there is a troubling similarity between them in their elision of the self as a self. Saying what he means in the mode of the philosopher or meaning what he says in the mode of the poet, how can the self both be and say itself? The misprision of Abraham's binding of Isaac in the thinking of Kierkegaard, who with Plato was one of Wittgenstein's favourite philosophers, is a telling opening into the question of the self in its responsibilities and its discontents.
Mapping bureaucratic overload: Dynamics and drivers in media coverage across three European countries
Authors: Lenz Alexa , Steinebach Yves , Casula Mattia 
Published: June 2024

AbstractBureaucratic overburdening has emerged as an important theme in public policy and administration research. The concept signifies a state where public administrators are overwhelmed with more tasks and responsibilities than they can effectively handle. Researchers attribute this phenomenon to several key factors, such as an increasing assault on the public sector, a growing volume of policies to enforce, and “external” shocks. These studies converge on the perception that the public sector's capacity to effectively implement policies and to address societal problems is progressively diminishing. However, there is a clear knowledge gap regarding the breadth, dynamics, and pervasiveness of this issue, as existing research often narrows its focus on the implementation of specific policies or policy sectors. This paper addresses this research gap by mapping the frequency of bureaucratic overload reports in newspaper articles from Italy, Ireland, and Germany, spanning two decades from 2003 to 2022. In the second step, we describe the drivers of overload that we coded in a random sample of articles. Our research reveals that the overburdening of public administration is indeed an escalating problem resulting from an “explosive” cocktail of external and internal challenges that simultaneously affect public authorities.
Correlation of non‐invasive psycho‐physiological and skin‐physiological measures
Authors: Schürer Nanna Y. , Symanzik Cara , Kukshausen Olga , Stürmer Ralf 
Published: June 2024

AbstractIntroductionPsychological stress alters epidermal barrier function. While intensive studies on the underlying mechanism have been performed in mice, human studies are limited. Non‐invasive skin‐physiology measures have not yet been directly linked to non‐invasive psycho‐physiological assessments.MethodsStandard measures of (I) transepidermal water loss prior to and after experimental barrier perturbation via tape stripping, (II) skin surface pH, (III) electrodermal activity, and (IV) heart rate function were taken over a 24 h time period. To document perceived stress, a standardized stress self‐assessment questionnaire, namely the Trierer Inventar zum chronischen Stress (TICS), was utilized.ResultsTwenty healthy, Caucasian (Fitzpatrick skin phototype I‐II), female volunteers (21–32 years, mean age 27, SD = 3.67 years) were included in this study (random sample). Significant correlations were shown for 24 h delta transepidermal water loss changes, that is, barrier repair kinetics (sympathetic activity) and heart rate variability (parasympathetic activity). Further correlations were noted for electrodermal activity and skin surface pH. Perceived stress, as documented by the TICS questionnaire, did not correlate with psycho‐ and skin physiological parameters, respectively.ConclusionThe presented approaches may provide a basis for non‐invasive objective research on the correlation between psychological stressors and epidermal barrier function.
A morphological analysis of calcium hydroxylapatite and poly‐l‐lactic acid biostimulator particles
Authors: McCarthy Alec D. , Hartmann Christian , Durkin Alan , Shahriar Shatil , Khalifian Saami , Xie Jingwei 
Published: June 2024

AbstractInjectable fillers, pivotal in aesthetic medicine, have evolved significantly with recent trends favoring biostimulators like calcium hydroxylapatite (CaHA‐CMC; Radiesse, Merz Aesthetics, Raleigh, NC) and poly‐l‐lactic acid (PLLA; Sculptra Aesthetics, Galderma, Dallas, TX). This study aims to compare the particle morphology of these two injectables and examine its potential clinical implications. Utilizing advanced light and scanning electron microscopy techniques, the physical characteristics of CaHA‐CMC and PLLA particles were analyzed, including shape, size, circularity, roundness, aspect ratio, and quantity of phagocytosable particles. The findings reveal several morphological contrasts: CaHA‐CMC particles exhibited a smooth, homogenous, spherical morphology with diameters predominantly ranging between 20 and 45 µm, while PLLA particles varied considerably in shape and size, appearing as micro flakes ranging from 2 to 150 µm in major axis length. The circularity and roundness of CaHA‐CMC particles were significantly higher compared to PLLA, indicating a more uniform shape. Aspect ratio analysis further underscored these differences, with CaHA‐CMC particles showing a closer resemblance to circles, unlike the more oblong PLLA particles. Quantification of the phagocytosable content of both injectables revealed a higher percentage of phagocytosable particles in PLLA. These morphological distinctions may influence the tissue response to each treatment. CaHA‐CMC's uniform, spherical particles may result in reduced inflammatory cell recruitment, whereas PLLA's heterogeneous particle morphology may evoke a more pronounced inflammatory response.
Associations between transfusion reactions and thromboembolism development in blood‐transfused patients: A retrospective cohort study
Authors: Chen Hsin‐Yu , Yin Chun‐Hao , Ou Shih‐Hsiang , Hsieh Ming‐Yun , Chen Yao‐Shen , Chen Jin‐Shuen 
Published: June 2024

AbstractBackgroundBlood transfusion (BT) may be associated with an increased risk of thromboembolism. The associations between transfusion reactions (TRs) during BTs and potential risk factors for the development of thromboembolism in patients underwent blood transfusion have not been analyzed. Therefore, this study aimed to compare risk factors associated with the development of venous thromboembolism (VTE) or pulmonary embolism (PE) between patients underwent blood transfusion with and without TRs.Study Designs and MethodsThe retrospective study was conducted between April 1, 2017, and March 31, 2020, at a medical center in Taiwan. Blood‐transfused patients were grouped into two cohorts as follows: those who experienced TRs and those who did not experience TRs. Both cohorts were subjected to follow‐up until March 31, 2021. The endpoints for both groups were the occurrence of VTE or PE or the date of March 31, 2021. To investigate between‐cohort risk differences, a Kaplan–Meier survival analysis and multiple Cox proportional hazard model was used.ResultsA total of 10,759 patients underwent 59,385 transfusion procedures, with 703 patients in the TR group, and 10,056 patients in the non‐TR group. The risk of VTE or PE was twice as high in the TR group than in the non‐TR group (adjusted hazard ratio 2.53, 95% confidence interval 1.49–4.29, p = .001). Meanwhile, age, female sex, transfusion frequency increment, and being nondiabetic was associated with an increased risk of developing thromboembolism.ConclusionTRs are associated with increased long‐term thromboembolism risk in patients underwent blood transfusion. It is imperative for clinicians to acknowledge this and maintain rigorous follow‐up.
Knowledge, skills, attitudes, beliefs, and implementation of evidence‐based practice among nurses in low‐ and middle‐income countries: A scoping review
Authors: Adombire Stephen , Baiden Deborah , Puts Martine , Puchalski Ritchie Lisa M. , Ani‐Amponsah Mary , Cranley Lisa 
Published: June 2024

AbstractBackgroundOver the past three decades, research studies on nurses' engagement in evidence‐based practice (EBP) have been widely reported, particularly in high‐income countries, with studies from these countries dominating literature reviews. As low‐ and middle‐income countries (LMICs) continue to join the EBP movement, primary research has emerged over the past decade about nurses' engagement with EBP.AimsThe aim of this scoping review was to identify the types and extent of published research regarding nurses' knowledge, skills, attitudes, beliefs, and implementation of EBP in LMICs.MethodsThe JBI scoping review methodology was used. Eight databases were searched up to November 2023. The review included primary studies (quantitative, qualitative, and mixed methods) that reported the knowledge, skills, attitudes, beliefs, or implementation of EBP among nurses in LMICs. Included studies focused on registered nurses in all healthcare settings within LMICs. Studies published in English were included with no limit on publication date. Two independent reviewers screened titles, abstracts, and full‐text articles of published studies. Data were analyzed quantitatively using frequencies and counts. Textual data from qualitative studies were analyzed using descriptive content analysis.ResultsFifty‐three publications were included, involving 20 LMICs. Studies were published between 2007 and 2023, with over 60% published in the past 7 years. Studies that evaluated familiarity/awareness of EBP showed that in general, nurses had low familiarity with or awareness of EBP. Most studies (60%) described nurses' attitudes toward EBP as positive, favorable, or high, and 31% as moderate. However, over 60% of studies described nurses' EBP knowledge/skills as moderate, low, or insufficient. Approximately 84% of studies described EBP implementation in healthcare settings as moderate, low, poor, or suboptimal.Linking Evidence to ActionStudies on nursing EBP have been increasing in LMICs for the past two decades, with findings highlighting opportunities for advancing EBP in nursing within LMICs. Health systems and healthcare organization leaders in LMICs should equip nurses with EBP knowledge and skills while providing the needed resources and support to ensure consistent implementation of EBP to improve health outcomes.