bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting customer intention to adopt mobile commerce in Jordan
Authors: Gharaibeh Malik Khlaif 
Published: April 2024

BACKGROUND The progress made in wireless communications has led to a higher adoption of mobile devices among users and has spurred the development of mobile commerce technology. OBJECTIVE This research examines the factors influencing the intention to adopt mobile commerce in Jordan. These factors include perceived usefulness, perceived ease of use, trust, social influence, personal innovation, and mobility. METHODS The study relied on Technology Acceptance Model (TAM), incorporating additional variables to suit the Jordanian context. The researchers gathered data from 540 users, and the research hypotheses were evaluated using smartPLS analysis. The study utilized a convenience sample due to the absence of a comprehensive list of names of mobile commerce users. RESULTS The results reveal that perceived usefulness, trust, social influence, personal innovation, and mobility play a significant role in influencing adoption intentions of mobile commerce. Furthermore, the study finds that mobility significantly affects the perceived usefulness of mobile commerce. In contrast, perceived ease of use does not show a statistically significant relationship on the intention to adopt mobile commerce. CONCLUSIONS The outcomes of this research provide valuable insights for companies, service developers, and mobile marketers, enabling them to enhance the adoption rate of this service among individuals.
Influence of toe flexor muscle fatigue on stiffness of the intrinsic foot muscles
Authors: Yoshida Kazushi , Katsuya Mikuto , Takano Shogo , Hayashi Kazuma , Hakozaki Taisei , Shinohara Junji 
Published: April 2024

BACKGROUND: Assessing intrinsic foot muscles (IFM) is important for understanding their role in loading movements. Additionally, knowledge of the impact of IFM following toe flexor muscle fatigue may aid the teaching of IFM exercises. OBJECTIVE: To examine the influence of toe flexor muscle fatigue on IFM stiffness using ultrasound shear-wave elastography. METHODS: This study included 19 college students. IFM stiffness at 10%, 50%, and 90% body weight was measured using ultrasound-based shear-wave elastography. IFM including the abductor hallucis (AbH), flexor hallucis brevis (FHB), flexor digitorum brevis (FDB), and quadratus plantae (QP) were assessed. The fatigue induction protocol comprised a series of toe flexions at a controlled pace of 40 beats per minute and an amplitude of 75% of the maximum toe flexor strength for a duration of 5 minutes. RESULTS: Muscle stiffness significantly increased with increasing load. Toe flexor muscle fatigue significantly increased the stiffness of the FDB. CONCLUSIONS: IFM stiffness significantly increased with increasing load, and the stiffness of FDB significantly increased in the toe flexor muscle fatigue condition at DLS and SLS loads. The findings of this study will contribute to the study and clinical setting of IFM exercises.
Examining a Preclinical Alzheimer’s Cognitive Composite for Telehealth Administration for Reliability Between In-Person and Remote Cognitive Testing with Neuroimaging Biomarkers
Authors: Duran Tugce , Gaussoin Sarah A. , Latham Lauren A. , Rundle Melissa M. , Espeland Mark A. , Williams Benjamin J. , Hughes Timothy M. , Craft Suzanne , Sachs Bonnie C. , Bateman James R. , Lockhart Samuel N. 
Published: April 2024

Background: The preclinical Alzheimer’s cognitive composite (PACC) was developed for in-person administration to capture subtle cognitive decline. At the outset of the COVID-19 pandemic, cognitive testing was increasingly performed remotely by telephone or video administration. It is desirable to have a harmonized composite measurement derived from both in-person and remote assessments for identifying cognitive changes and to examine its relationship with common neuroimaging biomarkers. Objective: We defined a telehealth compatible PACC (tPACC) and examined its relationship with neuroimaging biomarkers related to neurodegeneration, brain function and perfusion, white matter integrity, and amyloid-β. Methods: We examined 648 participants’ neuroimaging and in-person and remote cognitive testing data from the Wake Forest Alzheimer’s Disease Research Center’s Clinical Core cohort (observational study) to calculate a modified PACC (PACC5-RAVLT) score and tPACC scores (in-person and remote). We performed Spearman/intraclass correlation coefficient (ICC) analyses for reliability of tPACC scores and linear regression models to evaluate associations between tPACC and neuroimaging. Bland-Altman plots for agreement were constructed across cognitively normal and impaired (mild cognitive impairment and dementia) participants. Results: There was a significant positive relationship between tPACCin - person and PACC5-RAVLT (Overall group: r2 = 0.94, N = 648), and tPACCin - person and tPACCremote (validation subgroup: ICC = 0.82, n = 53). Overall, tPACC showed significant associations with brain thickness/volume, gray matter perfusion, white matter free water, and amyloid-β deposition. Conclusions: There is a good agreement between tPACCand PACC5-RAVLTfor cognitively normal and impaired individuals. The tPACC is associated with common neuroimaging markers of Alzheimer’s disease.
From the chokeberry fruit products and by-products to health-promoting effects through multifaceted in vitro bioactivity evaluation and molecular docking studies
Authors: Milutinović Milica , Ćujić Nikolić Nada , Radan Milica , Mihajilov Krstev Tatjana , Šavikin Katarina , Petrović Predrag , Randjelović Milica , Miladinović Bojana , Branković Suzana , Kitić Dušanka 
Published: April 2024

BACKGROUND: Polyphenolic-rich chokeberry extracts and juice could provide health benefits in humans. Moreover, by-products after processing stand out as a potential new source of valuable compounds. OBJECTIVE: The research aimed to evaluate in vitro bioactivity of chokeberry fruit extract, juice, and waste extract (material remaining after juice processing) based on their chemical composition and molecular docking analysis. METHODS: Spectrophotometric methods were used to determine the phenolics, anthocyanins, flavonoids, and proanthocyanins content in freeze-dried samples. Additionally, individual anthocyanins, flavonoids, and sugars were identified through HPLC analysis. The antioxidant capacity was tested using two in vitro methods and assessing antimicrobial activity. The effects of tyrosinase and acetylcholinesterase inhibition were examined using spectrophotometric methods. Molecular docking analysis identified the interaction of chokeberry components with the active sites of these enzymes. RESULTS: The waste extract exhibited the most robust antioxidant activity within the DPPH system. While bactericidal activity was absent across all chokeberry preparations, they demonstrated inhibitory effects on specific microbiological strains relevant to the gastrointestinal tract. Results revealed the chokeberry products’ ability to inhibit tyrosinase and acetylcholinesterase. Molecular docking confirmed the strong interactions between chokeberry compounds and these enzymes. CONCLUSION: The results indicate the potential of chokeberry products and by-products as valuable resources for pharmaceutical applications.
Felis bee optimization-based localization for energy-efficient communication in IoT-assisted WSN
Authors: Sawant Surabhi Sushant , Helonde Jagdish B. , Burade Prakash G. 
Published: April 2024

Localization of WSN sensor nodes gains significance in order to grasp the idea for dead node replacement and re-establishing the network from data loss. In this research, the node localization and the position estimation of the dead nodes during routing are more effectively identified by the Felis bee localization protocol. The node localization is significant for effective communication and data transfer throughout the network with high signal strength. The developed approach assists in identifying the dead nodes and replaces them with less localization error thus, the signal strength of the receiver side is maximum. By utilizing the information on the exact position of the anchor nodes, the unknown location of the dead nodes is estimated by the Felis bee localization protocol. The Felis bee localization protocol enhances the potential of node localization concerning the energy, localization error, and multi-objective function, and attains the minimum RMSE as 0.566 at the 25th round, maximum RSSI as −47.925 dBm as well as the Energy at round 25 as 0.6517 J and the Throughput as 0.2952bps over the simulation area of 10 × 100. Further the established localization reaches the minimum RMSE as 0.673, the maximum Energy as 0.5141 J, maximum throughput as 0.5682,and the maximum RSSI as −53.911 dBm, at the 50th round over simulation area 200 × 200 and surpasses other conventional localization techniques.
Upper Limbs Muscle Co-Contraction Changes Correlate With The Physical Motor Impairments in CMT
Authors: Lencioni Tiziana , Bandini Virginia , Schenone Cristina , Lagostina Maria , Aiello Alessia , Schenone Angelo , Ferrarin Maurizio , Trompetto Carlo , Mori Laura ,   CMT-RF Study Group, Germanotta Marco , Pazzaglia Costanza , Massucco Sara , Marinelli Lucio , Grandis Marina 
Published: April 2024

Background: Subjects with Charcot-Marie-Tooth (CMT) disease show hands impairment which is a relevant problem affecting the quality of life. This symptom is related to muscle weakness and reduced motor coordination of the upper limb. However, most studies focus on lower limb impairment, therefore the investigation of upper limb disability is necessary to identify biomarkers able to monitor disease-specific features and to tailor rehabilitation. Objective: This study aimed at characterizing upper limb muscle co-contraction using the co-contraction index (CCI) in CMT population. Methods: Upper limb kinematic and electromyography (EMG) data were collected from fourteen CMT subjects (6-CMT1A and 8-CMT1X) during motor tasks typical of daily living activities. Rudolph’s CCI was used to quantify muscle co-contraction of four muscle pairs acting on shoulder, elbow and wrist. All CMT subjects underwent clinical examination. Thirteen healthy subjects served as the normative reference (HC). Results: CMT1X and CMT1A showed a significant reduction in CCI for distal and proximal muscle pairs compared to HC. Furthermore, CMT1A showed greater values of CCI compared to CMT1X mainly for the axial and axial-to-proximal muscle pairs. Movement speed and smoothness were not altered compared to HC. In addition, EMG metrics showed moderate-to-strong significant correlations with clinical outcomes. Conclusions: CCI was able to quantify disease-specific deficits with respect to the normative reference, highlighting motor control alterations even before motor output impairment. CCI was also sensitive in detecting CMT subtypes-based differences and adopted compensatory strategies. Our findings suggest that CCI can be an outcome measure for CMT disease monitoring and interventional studies.
Analysis of varietal advantages of leaf form <i>Apium graveolens</i> L. according to chlorogenic acid content
Authors: Surbeeva E. S. , Efremova U. A. , Shurakova V. S. , Vishnyakov E. V. , Terninko I. I. 
Published: April 2024

Introduction. Special studies on the benefits of agricultural crops – current research regarding the prospects for the development of their products based on functional and specialized nutrition. Substances with a phenolic profile carry out various types of pharmacological activity aimed at treating metabolic and other socially significant phenomena, which allows them to be positioned as generally accepted main ingredients. The leafy botanical form of celery is a rich source of phenolic compounds.Aim. Development and validation of a method for the quantitative analysis of chlorogenic acid to assess the varietal advantages of Apium graveolens L. raw materials using HPLC.Materials and methods. For the analysis, we used leaf celery grass of different varieties grown at two sites (the village of Lembolovo and SNT "Ruchey"). Sample preparation of raw materials was carried out by extraction in an ultrasonic bath. Chromatography conditions: column Luna 5 μm C 18(100) Å LC Column 250 × 4.6 mm, thermostat temperature 40 °C, detection wavelength 327 nm. PF A 0.05 % TFA, PF B acetonitrile. Elution mode: 0 min 12 % B, 20 min 30 % PF B, 23 min 12 % PF B.Results and discussion. According to the data obtained, the accumulation of chlorogenic acid in celery raw materials depends on both the plant variety and the cultivation conditions. However, the difference in the quantitative content of the target component correlates between varieties grown on different sites. The highest content of chlorogenic acid was noted in the variety Nezhny (SNT "Ruchey") and amounted to 0.464 ± 0.012. The variety Summer Boom can be distinguished as the best variety.Conclusion. The results of the study can be used in the development and quality control of functional and specialized nutrition based on the leafy botanical form of odorous celery due to the high content of phenolic substances.
Impact of Weirs on Decomposition Rates of Dombeya goetzenii (K. Schum) Leaf Litter in the River Njoro, Kenya
Authors: Kipnusu Evagzard Korir , M´Erimba Charles Mwithali , Mbaka John Gichimu 
Published: April 2024

Water storage impoundments have deleterious effects on the structure and functioning of running water ecosystems. Many studies have been undertaken on the impacts of large impoundments on river ecosystems. However, comparatively few researches have determined the impact of small weirs on the functioning and structure of running water ecosystems. The main objective of the current study was to determine the impact of weirs on the decomposition rates of Dombeya goetzenii leaf litter in the Njoro River. The study was undertaken at five study sites located along the middle reaches of the Njoro River, near Egerton University, between November 2021 and January 2022. Four study sites were situated at upstream and downstream areas (i.e., approximately 10 m) of two weirs (i.e., Treetops and Canning weirs). A reference site was situated approximately 100 m upstream from the impoundment of the first weir. Physicochemical factors such as temperature, conductivity and nutrients (e.g., nitrates, ammonium) were determined at each study site. Additionally, decomposition rates of one of the most common tree species (i.e., Dombeya goetzenii) found growing along the Njoro River were determined. Leaf litter decomposition was determined using fine (100 µm) and coarse (500 µm) mesh litter bags and the negative exponential decay model was used to estimate decomposition rates (-k per day). The mean leaf litter decomposition rate was highest at the reference site (-k/day = 0.04) and lowest (-k/day = 0.02) at the upstream side of the first weir (i.e., Treetops weir).Leaf litter decomposition rates differed significantly (p = 0.002) between the aforementioned sites. Weirs had a significant local effect on the decomposition rates of Dombeya goetzenii leaf litter. The study provides crucial information to managers of riverine ecosystems about the impact of water storage weirs on an ecosystem function. The concerned government agencies should take action to prevent negative effects of weirs on riverine ecosystems.
Re-Energizing Gender Learning in the Context of the Competency Based Curriculum in Kenya
Authors: Mandela Rubai 
Published: April 2024

This paper is informed by a desk review of research reports, policy document, books, journal papers and other online resources focusing on gender learning and Competency Based Curriculum (CBC). An informal discussion of the data that arose from the desk review was done with six gender experts of balanced gender from Women Educational Researchers of Kenya (WERK), mainly for purposes of quality control. The paper sheds light on gender learning as well as the key principles of CBC in Kenya. It highlights gender inequalities, biases and stereotypes in Kenyan schools and communities, and how they are perpetuated through school. Additionally, the paper demonstrates how CBC could promote gender learning, equality and equity. In this connection, a reflection is made on how girls could be supported in STEM, how community service learning provides a perfect avenue for gender learning and the question of textbook review for gender learning. Among other recommendations, clear policies on gender ought to be developed to guide CBC activities.
Charting climate adaptation integration in smart building rating systems: a comparative study
Authors: Khoja Ahmed , Danylenko Olena 
Published: April 2024

Introduction:As the world is engulfed with the growing impacts of climate change, the integration of climate adaptation measures into building performance requirements is essential. In the era of the fourth industrial revolution, smart buildings are expected to be the next frontier in the realm of building rating systems after sustainability-based one. Smart buildings can play a pivotal role in addressing the evolving challenges of changing climate due to their temporal and spatial cross-scale nature.Methods:This study assesses the integration of climate hazard adaptation options within four prominent smart building rating systems (SBRS). Using a sectoral analysis approach and a 4-point Likert scale, we systematically evaluate the extent to which these rating systems incorporate climate adaptation measures directly or indirectly across multiple building sectors. We identify strengths and weaknesses in each system’s approach, highlighting areas where adaptation options are more profoundly addressed and sectors that require further attention.Results:The evaluation results reveal variations in the comprehensiveness of climate adaptation integration among the smart building rating systems. The SRBS show a high level of integration of climate adaptation measures in the urban sectors intrinsically tied to the smart building paradigm, such as communication sector, and the human wellbeing and organization sector. Nevertheless, the study also revealed that SBRS almost universally fall short in covering other vital domains such as building envelope and structure, water and sanitation, and blue and green infrastructure.Discussions:Complementing the SBRS with sustainability rating systems (GBRS) can effectively address the limitations in climate adaptation integration within SBRS. Moreover, the inherent interconnectedness of smart buildings with their surrounding infrastructure and the broader urban environment underscores the importance of the cross-scale consideration in the building rating domain in general and in climate related topics in particular, this interconnectedness also highlights a smart building’s reliance on its surrounding context for optimal functionality and the interdependency between the building and urban scale.
Green synthesis, structure–activity relationships, in silico molecular docking, and antifungal activities of novel prenylated chalcones
Authors: Godara Rajni , Kaushik Parshant , Tripathi Kailashpati , Kumar Rakesh , Rana Virendra Singh , Kumar Rajesh , Mandal Abhishek , Shanmugam V. , Pankaj  , Shakil Najam Akhtar 
Published: April 2024

A series of 16 novel prenylated chalcones (5A-5P) was synthesized by microwave-assisted green synthesis using 5-prenyloxy-2-hydroxyacetophenone and different benzaldehydes. Comparisons were also performed between the microwave and conventional methods in terms of the reaction times and yields of all compounds, where the reaction times in the microwave and conventional methods were 1–4 min and 12–48 h, respectively. The synthesized compounds were characterized using different spectroscopic techniques, including IR, 1H-NMR, 13C-NMR, and LC-HRMS. The antifungal activities of all compounds were evaluated against Sclerotium rolfsii and Fusarium oxysporum under in vitro conditions and were additionally supported by structure–activity relationship (SAR) and molecular docking studies. Out of the 16 compounds screened, 2’-hydroxy-4-benzyloxy-5’-O-prenylchalcone (5P) showed the highest activity against both S. rolfsii and F. oxysporum, with ED50 of 25.02 and 31.87 mg/L, respectively. The molecular docking studies of the prenylated chalcones within the active sites of the EF1α and RPB2 gene sequences and FoCut5a sequence as the respective receptors for S. rolfsii and F. oxysporum revealed the importance of the compounds, where the binding energies of the docked molecules ranged from −38.3538 to −26.6837 kcal/mol for S. rolfsii and −43.400 to −23.839 kcal/mol for F. oxysporum. Additional docking parameters showed that these compounds formed stable complexes with the protein molecules.
Global burden of stroke attributable to high systolic blood pressure in 204 countries and territories, 1990–2019
Authors: Li Junxiao , Zhong Qiongqiong , Yuan Shixiang , Zhu Feng 
Published: April 2024

BackgroundHigh systolic blood pressure (HSBP) is severely related to stroke, although the global burden of stroke associated with HSBP needs to be understood.Materials and methodsData derived from the Global Burden of Disease, Injuries, and Risk Factors Study were used to analyze deaths, disability-adjusted life years (DALYs), age-standardized rates of mortality (ASMR), age-standardized rates of DALY (ASDR), and estimated annual percentage change (EAPC).ResultsGlobally, 52.57% of deaths and 55.54% of DALYs from stroke were attributable to HSBP in 2019, with higher levels in men; the ASMRs and ASDRs in 1990–2019 experienced a decline of 34.89% and 31.71%, respectively, with the highest ASMR- and ASDR-related EAPCs in women. The middle socio-demographic index (SDI) regions showed the most numbers of deaths and DALYs in 2019 and 1990, with a decline in ASMR and ASDR; East Asia shared over 33% of global deaths and DALYs; Central Asia shared the highest ASMR and ASDR; high-income Asia Pacific experienced the highest decline in the ASMR- and ASDR-related EAPCs. Central and Southeast Asia had the highest percentages for deaths and DALYs, respectively, with more ASMR in high-middle SDI; the SDI and human development index were negatively associated with ASMR/ASDR and ASMR/ASDR-related EAPCs in 2019.ConclusionGlobal deaths and DALYs of stroke attributable to HSBP but none of their age-standardized rates have been on the rise over the past three decades; its disease burden focused especially on men aged 70 years and older in East, Central, and Southeast Asia, and the middle to high SDI regions.