bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coherent gluon radiation: beyond leading-log accuracy
Authors: Jackson Greg , Peigné Stéphane , Watanabe Kazuhiro 
Published: May 2024

Abstract
Results are presented for the medium-induced, soft coherent radiation spectrum for all 2 → 2 partonic channels in QCD, at leading-order in αs but beyond leading logarithmic accuracy. The general formula is valid in the full kinematic range of the underlying process, and reduces to previous results in special cases. The soft gluon radiation spectrum is expressed in terms of the color density matrix specific to each channel, quantifying the entanglement between the color components of the 2 → 2 production amplitude. Beyond the leading logarithm, the spectrum depends explicitly on the off-diagonal elements of this matrix, owing to the soft gluon’s ability to probe the internal color structure of the parton pair.
Celestial gluon amplitudes from the outside in
Authors: Melton Walker , Narayanan Sruthi A. 
Published: May 2024

Abstract
We show that, given a two-dimensional realization of the celestial OPE in self-dual Yang-Mills, we can find a scalar source around which scattering amplitudes replicate correlation functions computed from the 2D ‘gluon’ operators in a limit where a dynamic massless scalar decouples. We derive conditions on the two-dimensional three-point correlation function so that such a source exists and give two particular examples of this construction, one in which gluons are constructed from vertex operators in the semiclassical limit of Liouville theory and another in which the soft gluons arise from generalized free fields. Finally, we identify a bulk dual to the level of the boundary Kac-Moody algebra and discuss moving beyond the decoupling limit.
Distribution Function and Nonincreasing Rearrangement of $${\mathbb {B}}{\mathbb {C}}$$-Valued Functions with $${\mathbb {B}} {\mathbb {C}}$$-Measure
Authors: Eryılmaz İlker 
Published: May 2024

AbstractThis paper investigates the distribution function and nonincreasing rearrangement of $$\mathbb{B}\mathbb{C}$$

B
C

-valued functions equipped with the hyperbolic norm. It begins by introducing the concept of the distribution function for $$ \mathbb{B}\mathbb{C}$$

B
C

-valued functions, which characterizes valuable insights into the behavior and structure of $$\mathbb{B}\mathbb{C}$$

B
C

-valued functions, allowing to analyze their properties and establish connections with other mathematical concepts. Next, the nonincreasing rearrangement of $$\mathbb{B}\mathbb{C}$$

B
C

-valued functions with the hyperbolic norm are studied. By exploring the nonincreasing rearrangement of $$\mathbb{B}\mathbb{C}$$

B
C

-valued functions, it is aimed to determine how the hyperbolic norm influences the rearrangement process and its impact on the function’s behavior and properties.
Proof of the Plethystic Murnaghan–Nakayama Rule Using Loehr’s Labelled Abacus
Authors: Turek Pavel 
Published: May 2024

AbstractThe plethystic Murnaghan–Nakayama rule describes how to decompose the product of a Schur function and a plethysm of the form $$p_r\circ h_m$$

p
r

∘

h
m

as a sum of Schur functions. We provide a short, entirely combinatorial proof of this rule using the labelled abaci introduced in Loehr (SIAM J Discrete Math 24(4):1356–1370, 2010).
Development of semisynthetic saponin immunostimulants
Authors: Bai Di , Kim Hyunjung , Wang Pengfei 
Published: May 2024

AbstractMany natural saponins demonstrate immunostimulatory adjuvant activities, but they also have some inherent drawbacks that limit their clinical use. To overcome these limitations, extensive structure-activity-relationship (SAR) studies have been conducted. The SAR studies of QS-21 and related saponins reveal that their respective fatty side chains are crucial for potentiating a strong cellular immune response. Replacing the hydrolytically unstable ester side chain in the C28 oligosaccharide domain with an amide side chain in the same domain or in the C3 branched trisaccharide domain is a viable approach for generating robust semisynthetic saponin immunostimulants. Given the striking resemblance of natural momordica saponins (MS) I and II to the deacylated Quillaja Saponaria (QS) saponins (e.g., QS-17, QS-18, and QS-21), incorporating an amide side chain into the more sustainable MS, instead of deacylated QS saponins, led to the discovery of MS-derived semisynthetic immunostimulatory adjuvants VSA-1 and VSA-2. This review focuses on the authors’ previous work on SAR studies of QS and MS saponins.
Dissociated cerebellar contributions to feedforward gait adaptation
Authors: Bunday Karen L. , Ellmers Toby J. , Wimalaratna M. Rashmi , Nadarajah Luxme , Bronstein Adolfo M. 
Published: May 2024

AbstractThe cerebellum is important for motor adaptation. Lesions to the vestibulo-cerebellum selectively cause gait ataxia. Here we investigate how such damage affects locomotor adaptation when performing the ‘broken escalator’ paradigm. Following an auditory cue, participants were required to step from the fixed surface onto a moving platform (akin to an airport travellator). The experiment included three conditions: 10 stationary (BEFORE), 15 moving (MOVING) and 10 stationary (AFTER) trials. We assessed both behavioural (gait approach velocity and trunk sway after stepping onto the moving platform) and neuromuscular outcomes (lower leg muscle activity, EMG). Unlike controls, cerebellar patients showed reduced after-effects (AFTER trials) with respect to gait approach velocity and leg EMG activity. However, patients with cerebellar damage maintain the ability to learn the trunk movement required to maximise stability after stepping onto the moving platform (i.e., reactive postural behaviours). Importantly, our findings reveal that these patients could even initiate these behaviours in a feedforward manner, leading to an after-effect. These findings reveal that the cerebellum is crucial for feedforward locomotor control, but that adaptive locomotor behaviours learned via feedback (i.e., reactive) mechanisms may be preserved following cerebellum damage.
Associations of cumulative voriconazole dose, treatment duration, and alkaline phosphatase with voriconazole-induced periostitis
Authors: Ashmeik Walid , Schirò Silvia , Joseph Gabby B. , Link Thomas M. 
Published: May 2024

Abstract
Objective
To investigate the associations of cumulative voriconazole dose, treatment duration, and alkaline phosphatase with voriconazole-induced periostitis.

Materials and methods
One hundred and thirty-one patients with voriconazole use were identified using a clinical informatics tool. Health record data including age, sex, immune status, alkaline phosphatase, voriconazole levels, voriconazole dose, frequency, and treatment duration were collected. Imaging studies during the duration of treatment were reviewed by two radiology trainees and imaging features of voriconazole-induced periostitis were confirmed by a board-certified musculoskeletal radiologist. The length, location in the body, location in the bone, type, and morphology of periostitis lesions were recorded. Incident voriconazole-induced periostitis was defined as new periostitis on imaging after 28 days or more of voriconazole treatment in the absence of an alternative diagnosis. Univariate Firth’s logistic regression models were performed using cumulative voriconazole dose, treatment duration, and average ALP as predictors and incident VIP as the outcome.

Results
There were nine patients with voriconazole-induced periostitis and 122 patients without voriconazole-induced periostitis. The most common lesion location in the body was the ribs (37%) and morphology was solid (44%). A 31.5-g increase in cumulative voriconazole dose was associated with 8% higher odds of incident periostitis. Increased treatment duration (63 days) and higher average alkaline phosphatase (50 IU/L) were associated with 7% higher odds of periostitis and 34% higher odds of periostitis, respectively.

Conclusion
Increased cumulative voriconazole dose, treatment duration, and average alkaline phosphatase were associated with higher odds of voriconazole-induced periostitis.
On the use of elliptic PDEs for the parameterisation of planar multipatch domains
Authors: Hinz Jochen , Buffa Annalisa 
Published: May 2024

AbstractThis paper presents a parameterisation framework based on (inverted) elliptic PDEs for addressing the planar parameterisation problem of finding a valid description of the domain’s interior given no more than a spline-based description of its boundary contours. The framework is geared towards isogeometric analysis (IGA) applications wherein the physical domain is comprised of more than four sides, hence requiring more than one patch. We adopt the concept of harmonic maps and propose several PDE-based problem formulations capable of finding a valid map between a convex parametric multipatch domain and the piecewise-smooth physical domain with an equal number of sides. In line with the isoparametric paradigm of IGA, we treat the parameterisation problem using techniques that are characteristic for the analysis step. As such, this study proposes several IGA-based numerical algorithms for the problem’s governing equations that can be effortlessly integrated into a well-developed IGA software suite. We augment the framework with mechanisms that enable controlling the parametric properties of the outcome. Parametric control is accomplished by, among other techniques, the introduction of a curvilinear coordinate system in the convex parametric domain, for which more general elliptic PDEs are adopted. Depending on the application, parametric control allows for building desired features into the computed map, such as homogeneous cell sizes or boundary layers.
Survival outcomes of neoadjuvant immunochemotherapy versus chemotherapy for locally advanced esophageal squamous cell carcinoma
Authors: Lv Huilai , Zhang Fan , Huang Chao , Xu Shi , Li Jiachen , Sun Bokang , Gai Chunyue , Liu Zhao , Wang Mingbo , Li Zhenhua , Tian Ziqiang 
Published: May 2024

Abstract
Purpose
Neoadjuvant chemotherapy (NCT) is the standard preoperative treatment for resectable locally advanced esophageal squamous cell carcinoma (ESCC). Some studies reported neoadjuvant immunochemotherapy (NICT) could improve pathological response with manageable safety. However, few studies have compared the efficacy and safety of NICT and NCT, especially survival outcomes. In this study, we compared the efficacy and safety of NICT and NCT after a median follow-up of 36.0 months.

Methods
This was a retrospective study with a 1:1 propensity score matching (PSM). Locally advanced ESCC patients treated with neoadjuvant sintilimab plus chemotherapy or chemotherapy followed by esophagectomy were reviewed. The primary outcome was recurrence-free survival (RFS).

Results
Forty-five patients were identified in each group by PSM. The pathological complete response (pCR) rate in NICT and NCT group were 28.9% and 8.9% (P = 0.02). The hazard ratio (HR) was 0.396 (95% CI 0.171–0.919, p = 0.025) for RFS and 0.377 (95% CI 0.145–0.981, p = 0.038) for overall survival (OS), 3-year RFS was 80.6% and 62.1%, 3-year OS was 86.2% and 68.1%. Patients with pCR, MPR or downstaging had better 3-year RFS and 3-year OS. The incidences of postoperative complications and treatment-related adverse events (TRAEs) were similar.

Conclusion
This trial preliminarily shows that NICT improves pathological and survival outcomes over NCT for resectable locally advanced ESCC, with acceptable and manageable safety.
Pilot-scale foam and cast-coated nanocellulose filters for water treatment
Authors: Byambatsogt Khatanbaatar , Jiang Qixiang , Jaiswal Aayush Kumar , Kunnari Vesa , Bismarck Alexander , Mautner Andreas 
Published: May 2024

AbstractA large variety of substances, for instance heavy metal ions from different sources including mining, industry, and agricultural activities, pollute fresh water sources. Bio-based adsorbents, such as cellulose nanofibers (CNF), have recently been introduced in the process of treating water to remove hazardous pollutants primarily owing to their natural abundance, non-toxicity, and renewability. Surface modification of CNF, e.g. by catalytically oxidising the primary C6-OH groups of CNF selectively into carboxylic (COO−) groups with TEMPO, yields materials that are effective in adsorbing positively charged heavy metal ions, e.g. Cu ions. However, to utilise CNF in continuous processes beyond static, batch-wise adsorption, in particular on (pre-)industrial scale, they need to be immobilised on filter substrates in thin layers and an efficient manner. In this work, we report bio-adsorbent-based filters prepared by coating TEMPO-CNF on viscose filters using two different pilot-scale coating approaches, foam and cast coating. The performance of TEMPO-CNF filters was evaluated in terms of their water permeance as well as adsorption of metal ions including Cu(II) and Ca(II). By foam coating thin layers could be fabricated in a time efficient way facilitating high adsorption capacities (52 mg g−1), whilst by cast coating higher amounts of TEMPO-CNF could be deposited allowing for adsorbing higher absolute amounts (280 mg m−2) of heavy metal ions.
Graphical abstract
Psychotherapie als „dritter Raum“. Kultursensible Ansätze in der systemischen Familientherapie
Authors: Bauer Nicole M. 
Published: May 2024

ZusammenfassungDas Wissen um die ‚kulturelle‘ Herkunft eines Menschen ist für die therapeutische Praxis ein bedeutender Orientierungsrahmen, der Aufschluss über Bezugssysteme, Werte, Normen und Weltbilder der Klient:innen darstellt. Sofern Psychotherapeut:innen und Klient:innen aus unterschiedlichen Kulturen, mit unterschiedlichen Werten, Normen und (religiösen) Weltbildern in psychotherapeutischen Settings aufeinandertreffen, stellt die Psychotherapie einen Austragungs- und Aushandlungsort von kultureller Identität, einen „dritten Raum“ dar. In Anlehnung an die postkoloniale Theorie des Kulturwissenschaftlers Homi K. Bhabha soll hier das Konzept des „dritten Raumes“ eingeführt werden, um den kulturellen Aspekt therapeutischer Begegnungen theoretisch zu verorten. Mit Fallbeispielen aus der systemischen Praxis soll zudem ein wichtiger Beitrag zur kultursensiblen Herangehensweise in der Psychotherapie geleistet werden.
Learning and implementation of TransREctus sheath PrePeritoneal procedure for inguinal hernia repair
Authors: Zwols T. L. R. , van der Bilt A. R. M. , Veeger N. J. G. M. , Möllers M. J. W. , Hess D. A. , Brandsma H. T. , Jutte E. , Veldman P. H. J. M. , Eker H. H. , Koning G. G. , Pierie J. P. E. N. 
Published: May 2024

Abstract
Purpose
The TransREctus sheath PrePeritoneal procedure (TREPP) was introduced as an alternative open and preperitoneal technique for inguinal hernia mesh repair, demonstrating safety and efficacy in retro- and prospective studies. However, little is known about the technique’s inherent learning curve. In this study, we aimed to determine TREPP learning curve effects after its implementation in high-volume surgical practice.

Methods
All primary, unilateral TREPP procedures performed in the first three years after implementation (between January 2016 and December 2018) were included out of a large preconstructed regional inguinal hernia database. Data were analyzed on outcome (i.e., surgical complications, hernia recurrences, postoperative pain). Learning curve effects were analyzed by assessing outcome in relation to surgeon experience.

Results
In total, 422 primary, unilateral TREPP procedures were performed in 419 patients. In three patients a unilateral TREPP procedure was performed on both sides separated in time. A total of 99 surgical complications were registered in 83 procedures (19.6% of all procedures), most commonly inguinal postoperative pain (8%) and bleeding complications (7%). Hernia recurrences were observed in 17 patients (4%). No statistically significant differences on outcome were found between different surgeon experience (< 40 procedures, 40–80 procedures, > 80 procedures).

Conclusion
Implementation of TREPP seems not to be associated with a notable increase of adverse events. We were not able to detect a clear learning curve limit, potentially suggesting a relatively short learning curve among already experienced hernia surgeons compared to other guideline techniques.
Next generation sequencing panel as an effective approach to genetic testing in patients with a highly variable phenotype of neuromuscular disorders
Authors: Radziwonik-Fraczyk Wiktoria , Elert-Dobkowska Ewelina , Karpinski Marek , Pilch Jacek , Ziora-Jakutowicz Karolina , Kubalska Jolanta , Szczesniak Dominika , Stepniak Iwona , Zaremba Jacek , Sulek Anna 
Published: May 2024

AbstractNeuromuscular disorders (NMDs) include a wide range of diseases affecting the peripheral nervous system. The genetic diagnoses are increasingly obtained with using the next generation sequencing (NGS). We applied the custom-design targeted NGS panel including 89 genes, together with genotyping and multiplex ligation-dependent probe amplification (MLPA) to identify a genetic spectrum of NMDs in 52 Polish patients. As a result, the genetic diagnosis was determined by NGS panel in 29 patients so its diagnostic utility is estimated at 55.8%. The most pathogenic variants were found in CLCN1, followed by CAPN3, SCN4A, and SGCA genes. Genotyping of myotonic dystrophy type 1 and 2 (DM1 and DM2) as a secondary approach has been performed. The co-occurrence of CAPN3 and CNBP mutations in one patient as well as DYSF and CNBP mutations in another suggests possibly more complex inheritance as well as expression of a phenotype. In 7 individuals with single nucleotide variant found in NGS testing, the MLPA of the CAPN3 gene was performed detecting the deletion encompassing exons 2—8 in the CAPN3 gene in one patient, confirming recessive limb-girdle muscular dystrophy type 1 (LGMDR1). Thirty patients obtained a genetic diagnosis (57.7%) after using NGS testing, genotyping and MLPA analysis. The study allowed for the identification of 27 known and 4 novel pathogenic/likely pathogenic variants and variants of uncertain significance (VUS) associated with NMDs.In conclusion, the diagnostic approach with diverse molecular techniques enables to broaden the mutational spectrum and maximizes the diagnostic yield. Furthermore, the co-occurrence of DM2 and LGMD has been detected in 2 individuals.
A GIS-based multi-criteria decision-making approach (GIS-MCDM) for determination of the most appropriate site selection of onshore wind farm in Adana, Turkey
Authors: Yaman Aydan 
Published: May 2024

AbstractEnergy stands as an indispensable global need, yet the finite nature of rapidly depleting fossil fuel reserves poses environmental challenges. To address this, numerous nations are shifting toward sustainable energy sources to foster environmental well-being while satisfying their energy requirements. Among these alternatives, wind energy emerges as a particularly efficient option. This study focuses on identifying optimal sites for installing wind power plants in Adana province through the integration of the analytic hierarchy process (AHP) and geographic information system (GIS). Within this framework, a comprehensive set of 15 criteria was delineated along with their respective sub-criteria. It is thought that the criteria used in the study will be useful not only for Adana province but also for other provinces that are suitable for wind turbine placement and planned to be built. The outcome of this investigation delineates potential areas in Adana province deemed suitable for establishing wind power plants. As a result, analysis reveals that 9.94% of the study area is conducive to establishing a wind farm (WF), while 51.66% is deemed moderately suitable. Notably, the districts of Feke, Tufanbeyli, Saimbeyli, and Pozantı emerge as particularly well-suited for this purpose. This study aims to contribute to the existing literature by identifying precise and suitable areas by combining GIS and AHP in the WF site selection process. In the study, a new research perspective is presented by taking into account the uncertainty in the site selection process and the concept of sustainability in three different dimensions: technical, economic, and environmental, thus aiming to guide decision-makers for future WF projects. In addition, it is thought that the methods and criteria used in the study will also be guiding for future WF site selection studies.
Graphical abstract
SVPath: A Deep Learning Tool for Analysis of Stria Vascularis from Histology Slides
Authors: Jain Aseem , Perdomo Dianela , Nagururu Nimesh , Li Jintong Alice , Ward Bryan K. , Lauer Amanda M. , Creighton Francis X. 
Published: May 2024

Abstract
Introduction
The stria vascularis (SV) may have a significant role in various otologic pathologies. Currently, researchers manually segment and analyze the stria vascularis to measure structural atrophy. Our group developed a tool, SVPath, that uses deep learning to extract and analyze the stria vascularis and its associated capillary bed from whole temporal bone histopathology slides (TBS).

Methods
This study used an internal dataset of 203 digitized hematoxylin and eosin-stained sections from a normal macaque ear and a separate external validation set of 10 sections from another normal macaque ear. SVPath employed deep learning methods YOLOv8 and nnUnet to detect and segment the SV features from TBS, respectively. The results from this process were analyzed with the SV Analysis Tool (SVAT) to measure SV capillaries and features related to SV morphology, including width, area, and cell count. Once the model was developed, both YOLOv8 and nnUnet were validated on external and internal datasets.

Results
YOLOv8 implementation achieved over 90% accuracy for cochlea and SV detection. nnUnet SV segmentation achieved a DICE score of 0.84–0.95; the capillary bed DICE score was 0.75–0.88. SVAT was applied to compare both the ears used in the study. There was no statistical difference in SV width, SV area, and average area of capillary between the two ears. There was a statistical difference between the two ears for the cell count per SV.

Conclusion
The proposed method accurately and efficiently analyzes the SV from temporal histopathology bone slides, creating a platform for researchers to understand the function of the SV further.
Conditions Underlying the Appearance of Spontaneous Otoacoustic Emissions in Mammals
Authors: Manley Geoffrey A. 
Published: May 2024

AbstractAcross the wide range of land vertebrate species, spontaneous otoacoustic emissions (SOAE) are common, but not always found. The reasons for the differences between species of the various groups in their emission patterns are often not well understood, particularly within mammals. This review examines the question as to what determines in mammals whether SOAE are emitted or not, and suggests that the coupling between hair-cell regions diminishes when the space constant of frequency distribution becomes larger. The reduced coupling is assumed to result in a greater likelihood of SOAE being emitted.