bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health inequality of rural-to-urban migrant workers in eastern China and its decomposition: a comparative cross-sectional study
Authors: Du Sisi , Yang Yufan , Zheng Miaomiao , Zhang Haiyan , Li Tingting , Cai Fuman 
Published: May 2024

ObjectivesAs a specific group with high health inequality, it is crucial to improve the health status and health inequalities of rural-to-urban migrant workers. This study aimed to evaluate the health inequality of migrant and urban workers in China and decompose it.MethodsA cross-sectional study was carried out, using a standardized questionnaire to obtain basic information, self-rated health to evaluate health status, concentration index to measure health inequalities, and WDW decomposition to analyze the causes of health inequalities.ResultsThe concentration index of health for migrants was 0.021 and 0.009 for urban workers. The main factors contributing to health inequality among rural-to-urban migrant workers included income, exercise, and age. In contrast, the main factors of health inequality among urban workers included income, the number of chronic diseases, social support, and education.ConclusionThere were health inequalities in both rural-to-urban migrant and urban workers. The government and relevant authorities should formulate timely policies and take targeted measures to reduce income disparities among workers, thereby improving health inequality.
General ability and specific cognitive functions are lower in children with epilepsy after perinatal ischemic stroke
Authors: Vaher Ulvi , Männamaa Mairi , Laugesaar Rael , Ilves Norman , Ilves Nigul , Loorits Dagmar , Kool Pille , Ilves Pilvi 
Published: May 2024

IntroductionEpilepsy develops in one third of children after perinatal stroke. Both epilepsy and stroke may be risk factors for impaired cognitive abilities. How the development of epilepsy is related to the cognitive profile of children with perinatal stroke is still unclear. The aim of the study was to evaluate general and specific cognitive functions in children with epilepsy and children without epilepsy after perinatal ischemic stroke.MethodsThe study group consisted of 51 children with perinatal ischemic stroke confirmed by magnetic resonance imaging: 27 (53%) children with arterial ischemic stroke and 24 (47%) with periventricular venous infarction. Magnetic resonance imaging and electroencephalography were performed in all patients after the neonatal period. Epilepsy was diagnosed if the child had at least two unprovoked seizures occurring &gt;24 h apart or one unprovoked seizure with a high recurrence risk. Cognitive assessments were performed using the Kaufman Assessment Battery for Children, Second Edition, at the age of ≥7 years. General ability (Fluid Crystallized Index, Mental Processing Index, Non-verbal Index) and specific cognitive functions (sequential processing, simultaneous processing, learning, planning, knowledge) were evaluated.ResultsAt the median age of 19.3 years (interquartile range 14.0–22) at the time of follow-up for epilepsy, 14 (27.5%) patients had developed epilepsy, and 37 (72.5%) patients were without epilepsy. All general cognitive ability scores were lower in children with epilepsy compared to children without epilepsy. Among specific cognitive functions, simultaneous processing, planning, and knowledge were lower in children with epilepsy compared to children without epilepsy: simultaneous processing mean [78.5, 95% CI: [69.8, 87.2], vs. 96.9, 95% CI [90, 103.9], p = 0.0018]; planning mean [82.5, 95% CI: [73, 92], vs. 96.2, 95% CI: [88.7, 103.6], p = 0.026]; knowledge median (25th, 75th percentile): 80.5 (75, 87) vs. 92 (84, 108), p = 0.023.ConclusionChildren with epilepsy after perinatal ischemic stroke have lower general cognitive abilities compared to children without epilepsy. The profile of the subscales indicates lower verbal abilities and executive functions in children with epilepsy. Children with post-stroke epilepsy need targeted cognitive monitoring for early aimed rehabilitation and for establishing an adapted learning environment.
Is transanal irrigation the best treatment possibility for low anterior resection syndrome? A multicenter, randomized clinical trial: study protocol
Authors: Klimovskij Michail , Civilka Ignas , Aleinikov Andrej , Aukstikalnis Tomas , Christensen Peter , Dulskas Audrius 
Published: May 2024

BackgroundUp to 50% of patients who undergo rectal resection suffer from various and partly severe functional problems, despite the preservation of the anal sphincter. These complaints are defined as low anterior resection syndrome (LARS). So far, there are no randomized clinical trials regarding the most effective treatment for LARS. Our aim is to evaluate whether transanal irrigation improves bowel function and quality of life in patients following low anterior resection compared to best supportive care.MethodsPatients who have undergone low anterior resection will be approached for this study. On patient's visit, complaints regarding the defecation as well as any deterioration in their overall quality of life will be assessed using questionnaires such as the Low Anterior Resection Syndromes score, Wexner score, European Organization for Research and Treatment of Cancer (EORTC) Quality of Life (QOL) CR-29, and Measure Yourself Medical Outcome Profile tool. Few additional target questions will be also asked, such as “Would you recommend the treatment to anybody; did you expect the improvement following the treatment; etc.” Questionnaires and scales will be filled on follow-up visits every 3 months for 1 year.DiscussionThis multicenter, randomized controlled trial will lead to a better understanding of LARS treatment. Moreover, it will be a hypothesis-generating study and will inform areas needing future prospective studies.
Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT05920681).
A New Genus of Praeaulacidae (Hymenoptera: Evanioidea) from Mid-Cretaceous Kachin Amber: Insights into a Putative New Praeaulacinae Subclade
Authors: Yang Jingtao , Jouault Corentin , Li Longfeng , Shih Chungkun , Ren Dong 
Published: May 2024

A new praeaulacid genus and species, Azygdellitha nova gen. et sp. nov., is described and illustrated based on a male specimen from mid-Cretaceous Kachin amber from Hukawng Valley, Myanmar. This newly discovered taxon increased the diversity of praeaulacid wasps during the Cretaceous period. While this new taxon shares similarities of wing venation with most species of the subfamily Praeaulacinae, it strongly differs from that of three genera previously described from mid-Cretaceous Kachin amber: Mesevania, Paleosyncrasis, and Praegastrinus. We explore the possibility that these genera constitute a distinct tribe within the Praeaulacinae, distinguished by their wing venation. We provide illustrations and emphasize the potentially diagnostic traits supporting this classification.
Baire 1 Functions and the Topology of Uniform Convergence on Compacta
Authors: Holá Ľubica , Holý Dušan 
Published: May 2024

Let X be a Tychonoff topological space, B1(X,R) be the space of real-valued Baire 1 functions on X and τUC be the topology of uniform convergence on compacta. The main purpose of this paper is to study cardinal invariants of (B1(X,R),τUC). We prove that the following conditions are equivalent: (1) (B1(X,R),τUC) is metrizable; (2) (B1(X,R),τUC) is completely metrizable; (3) (B1(X,R),τUC) is Čech-complete; and (4) X is hemicompact. It is also proven that if X is a separable metric space with a non isolated point, then the topology of uniform convergence on compacta on B1(X,R) is seen to behave like a metric topology in the sense that the weight, netweight, density, Lindelof number and cellularity are all equal for this topology and they are equal to c= |B1(X,R)|. We find further conditions on X under which these cardinal invariants coincide on B1(X,R).
Metabolic Engineering of Corynebacterium glutamicum for the Production of Flavonoids and Stilbenoids
Authors: Chu Luan Luong , Tran Chau T. Bang , Pham Duyen T. Kieu , Nguyen Hoa T. An , Nguyen Mi Ha , Pham Nhung Mai , Nguyen Anh T. Van , Phan Dung T. , Do Ha Minh , Nguyen Quang Huy 
Published: May 2024

Flavonoids and stilbenoids, crucial secondary metabolites abundant in plants and fungi, display diverse biological and pharmaceutical activities, including potent antioxidant, anti-inflammatory, and antimicrobial effects. However, conventional production methods, such as chemical synthesis and plant extraction, face challenges in sustainability and yield. Hence, there is a notable shift towards biological production using microorganisms like Escherichia coli and yeast. Yet, the drawbacks of using E. coli and yeast as hosts for these compounds persist. For instance, yeast’s complex glycosylation profile can lead to intricate protein production scenarios, including hyperglycosylation issues. Consequently, Corynebacterium glutamicum emerges as a promising alternative, given its adaptability and recent advances in metabolic engineering. Although extensively used in biotechnological applications, the potential production of flavonoid and stilbenoid in engineered C. glutamicum remains largely untapped compared to E. coli. This review explores the potential of metabolic engineering in C. glutamicum for biosynthesis, highlighting its versatility as a cell factory and assessing optimization strategies for these pathways. Additionally, various metabolic engineering methods, including genomic editing and biosensors, and cofactor regeneration are evaluated, with a focus on C. glutamicum. Through comprehensive discussion, the review offers insights into future perspectives in production, aiding researchers and industry professionals in the field.
A Multifunctional Nanocatalytic Metal-Organic Framework as a Ferroptosis Amplifier for Mild Hyperthermia Photothermal Therapy
Authors: Deng Ying , Wang Duo , Zhao Wenhua , Qiu Guanhua , Zhu Xiaoqi , Wang Qin , Qin Tian , Tang Jiali , Jiang Jinghang , Lin Ningjing , Wei Lili , Liu Yichen , Xie Yuan , Chen Jie , Deng Liu , Liu Junjie 
Published: May 2024

Hyperthermia therapy is considered an effective anticancer strategy. However, high temperature can trigger an excessive inflammatory response, leading to tumor self-protection, immunosuppression, metastasis, and recurrence. To address this issue, we reported a multifunctional photothermal nanoplatform to achieve mild hyperthermia photothermal therapy (mild PTT) based on cisplatin (DDP) and a ferrocene metal-organic framework (MOF-Fc) nanocomposite, which can specifically enhance ferroptosis-triggered oxidative stress levels and synchronously amplify mild hyperthermia PTT-mediated anticancer responses. Both in vitro and in vivo antineoplastic results verify the superiority of mild PTT with DDP/MOF-Fc@HA. The combination of DDP and MOF-Fc exhibits Fenton catalytic activity and glutathione depletion capacity, magnifying mild hyperthermia effects via the radical oxygen species (ROS)-adenosine triphosphate (ATP)-HSP silencing pathway, with important implications for clinical hyperthermia therapy.
LITERATURE REVIEW TERAPI BERMAIN PUZZLE TERHADAP PERKEMBANGAN MOTORIK HALUS PADA ANAK PRASEKOLAH
Authors: Aryanti  , Sari Yona , Fatrin Tiara , Aprianto  , Novita Sari Muthiah 
Published: May 2024

Anak prasekolah adalah anak yang berusia 3-6 tahun dimana usia ini merupakan usia emas (golden age) yang harus distimulasi perkembangannya salah satunya adalah perkembangan motorik. Data WHO tahun 2009 mengatakan bahwa 5-25% anak prasekolah di dunia mengalami gangguan motorik halus. Data UNICEF Tahun 2011 juga mengatakan 27,5% atau 3 juta anak di dunia mengalami keterlambatan motorik halus. Kemampuan motorik dapat dikembangkan dengan bermain yang berhubungan dengan keterampilan fisik yang juga melibatkan otot kecil serta koordinasi mata dan tangan salah satunya bermain puzzle. Penelitian ini bertujuan untuk mengetahui pengaruh terapi bermain puzzle terhadap perkembangan motorik halus pada anak prasekolah. Penelitian ini menggunakan studi literature dengan menganalisis terhadap hasil penelusuran jurnal (e-journal) dan artikel dengan tinjauan teori yang ada (e-book), jurnal yang telah di review sebanyak 9 jurnal Nasional. Literature review menunjukan persamaan hasil dari 9 jurnal yang di review, bahwa bermain puzzle dapat memberikan pengaruh terhadap perkembangan motorik halus pada anak prasekolah. Memberikan stimulasi seperti bermain puzzle kepada anak dapat meningkatkan kemampuan motorik halus pada anak sehingga dapat mengurangi angka kejadian anak dengan keterlambatan perkembangan motorik halus.
Kata Kunci : Puzzle, Motorik Halus, Prasekolah
PENGARUH PEMBERIAN AROMATERAPI LAVENDER TERHADAP TINGKAT KECEMASAN IBU BERSALIN KALA I DI PMB HJ. ZURRAHMI, SST, SKM PEKANBARU
Authors: Nurhayati Sindi , Nadia Fatma , Sari Tanberika Fajar 
Published: May 2024

Selama persalinan kala I, seorang wanita akan mengalami gangguan psikologi yaitu kecemasan. Di Indonesia tahun 2020 terdapat 373.000.000 orang ibu hamil, yang mengalami kecemasan dalam menghadapi persalinan ada sebanyak 107.000.000 orang (28,7%). Salah satu cara untuk mengurangi kecemasan yaitu dengan terapi non farmakologi menggunakan aromaterapi lavender, penggunaannya dengan cara inhalasi menggunakan diffuser. Tujuan penelitian untuk mengetahui pengaruh pemberian aromaterapi lavender terhadap tingkat kecemasan ibu bersalin kala I di PMB Hj. Zurrahmi, SST, SKM Pekanbaru yang dilaksanakan pada Februari – Oktober 2023. Jenis penelitian Kuantitatif dengan rancangan Pre Experiment, dengan one group pre test and post test design. Populasi penelitian ibu bersalin di PMB Hj. Zurrahmi, SST, SKM : dengan sampel 15 responden secara purpossive sampling. Instrumen penelitian menggunakan lembar observasi Hamilton Axiety Rating Scale (HARS). Analisis data dengan Wilcoxon Signed Ranks Test. Hasil penelitian sebelum diberikan aromaterapi lavender mayoritas responden mengalami kecemasan sedang (73,3%), sesudah diberikan mayoritas kecemasan ringan (80,0%). Terdapat pengaruh pemberian aromaterapi lavender dengan P-Value 0,000<0,05. Diharapkan kepada PMB Hj. Zurrahmi SST, SKM dapat menggunakan aromaterapi lavender sebagai alternatif mengurangi kecemasan pada ibu bersalin.
Autonomous clustering by fast find of mass and distance peaks
Authors: Yang Jie , Lin Chin-Teng 
Published: May 2024

Clustering is a fundamental tool of scientific analysis, ubiquitous in
disciplines from biology and chemistry to astronomy and pattern
recognition. We propose a novel clustering algorithm based on the
natural idea that a cluster and its nearest neighbor with higher mass
should be merged into one cluster, unless they both have relatively
large masses and the distance between them is also relatively large. The
find of mass and distance peaks reveals the mergers that don’t conform
to the rule and should be removed. The algorithm is parameter-free and
harnesses this idea to recognize any cluster and find the proper number
of clusters and noise autonomously. Experiments on numerous synthetic
and real-world data sets show the enormous versatility of the proposed
algorithm that remarkably outperforms the best compared algorithm.
Additionally, we also compare it with latest state-of-the-art deep
clustering algorithms on several challenging image data sets. The
proposed algorithm without any deep representation achieves better or
close performance than deep clustering algorithms on image clustering.
Our codes are
available: https://github.com/JieYangBruce/TorqueClustering .
Bacillus velezensis B63 and chitosan control root rot, improve growth and alter the rhizosphere microbiome of geranium
Authors: ELSAYED Tarek R. , EL-SAID Nadia A.M. , SAFHI Fatmah A. , REYAD Nour El Houda A. 
Published: May 2024

The root rot complex of geranium plants caused by Rhizoctonia solani and Macrophomina phaseolina is a major threat, and control of these pathogens predominantly relies on chemicals. This study explored multifaceted applications of Bacillus velezensis (strain B63) and chitosan, assessing their biocontrol efficacy against root rot, and their subsequent effects on rhizosphere communities. Strain B63 was antagonistic to R. solani and M. phaseolina. Under field conditions, greatest efficacy was obtained with strain B63 (36% and 33% disease reductions in, respectively, two growing seasons), chitosan soaking + foliar spray 0.2% (CSF 0.2%) (33 and 27% reductions), and 0.1% chitosan soaking + foliar spray (CSF 0.1%) (33 and 26% reductions). These treatments also changed rhizosphere microbiota, as shown by numbers of colony-forming units (CFU) and 16S rRNA gene microbiome analyses. Concomitant with rhizosphere shifts, essential oil yields and composition were positively affected, as shown by gas chromatography analyses. Chitosan soaking + foliar spray 0.2% increased concentrations of citronellol (1.36-fold), geraniol (1.37-fold), citronellyl formate (1.54-fold), and geranyl formate (1.94-fold) in geranium essential oil, compared with the experimental controls. Strain B63 also increased these essential oils by 1.04- to 1.27-fold. B63 also enhanced eugenol levels by 1.35-fold. Treatments with B63 were more effective than chitosan in improving the geranium plant morphological parameters (plant height, numbers of branches, biomass). These results show that B. velezensis strain B63 treatments have potential for enhancing yields and product quality from geranium plant under root rot infection.
Tinjauan Pustaka Penggunaan Gawai dengan Kejadian Miopia
Authors: Anugrahsari Santi , Nugraha Abraham William , Septrilla Gladys , Franesta Veronica Agrippina 
Published: May 2024

Abstrak
Perubahan gaya hidup pada masa pandemi mempengaruhi kehidupan mayoritas manusia di dunia. Perubahan gaya hidup, terutama peningkatan durasi dan frekuensi penggunaan gawai untuk berbagai keperluan hidup dapat menimbulkan berbagai efek samping seperti berbagai kelainan refraksi, terutama miopia. Studi ini dilakukan dengan tujuan mengevaluasi korelasi penggunaan gawai dengan miopia dan parameter biometrik mata yang relevan seperti panjang aksial bola mata dan spherical equivalent. Sumber literatur dari database elektronik menggunakan NCBI, ProQuest dan Google Scholar dengan kata kunci dalam Bahasa Inggris “Gadget”, “Myopia”, dan “Vision Impairment” dan dalam Bahasa Indonesia “Gawai”, “Miopi”, dan “Kelainan Refraksi”. Artikel yang ditemukan dipublikasi dari Januari 2012 hingga Juni 2022 kemudian diseleksi untuk menurut objektif studi ini dan didapatkan limabelas jurnal yang digunakan dalam studi ini. Jarak penggunaan gawai mempunyai korelasi dengan kelainan miopia. Posisi berbaring juga ditemukan mempunyai hubungan dengan kelainan miopia. Sementara durasi penggunaan gawai ditemukan tidak mempunyai korelasi dengan kelainan myopia Penggunaan gawai dapat menjadi salah satu faktor risiko terjadinya kelainan refraksi. Berdasarkan penelitian yang sudah terkumpulkan, diketahui jarak penggunaan gawai <30 cm dan posisi penggunaan gawai secara berbaring memiliki hubungan dengan kejadian kelainan refraksi sedangkan durasi penggunaan gawai tidak memiliki hubungan signifikan dengan kejadian kelainan refraksi seperti miopia.

Kata kunci: gawai, kelainan refraksi, miopia
La leyenda de Teófilo: entre el pacto diabólico y la intervención marianaLa leyenda de Teófilo: entre el pacto diabólico y la intervención marianaLa leyenda de Teófilo: entre el pacto diabólico y la intervención marianaLa leyenda de Teófilo: entre el p
Authors: Martínez Adriana 
Published: May 2024

La leyenda de Teófilo como otras tantas historias milagrosas aparece en Oriente, sin embargo las relaciones que se establecen entre Bizancio y el Occidente latino durante el período carolingio hace que esta narración llegue a la corte carolingia. Si bien allí se gesta el corpus de versiones es a partir del siglo XII que alcanza una importante difusión. En el llamado siglo mariano donde abundan los relatos de milagros de la Virgen esta leyenda de rasgos distintivos tan sugerentes como el pacto con el Diablo desencadena una numerosa producción literaria así como una abundante plasmación icónica. Nuestra propuesta se focalizará en el desarrollo discursivo imago-textual de la leyenda, especialmente en el proceso de falta, remordimiento y posterior arrepentimiento del protagonista y en la elección de un momento puntual del relato, para relevar los recursos utilizados para manifestar los conceptos fundantes del cristianismo como son el pecado y la redención.
La leyenda de Teófilo como otras tantas historias milagrosas aparece en Oriente, sin embargo las relaciones que se establecen entre Bizancio y el Occidente latino durante el período carolingio hace que esta narración llegue a la corte carolingia. Si bien allí se gesta el corpus de versiones es a partir del siglo XII que alcanza una importante difusión. En el llamado siglo mariano donde abundan los relatos de milagros de la Virgen esta leyenda de rasgos distintivos tan sugerentes como el pacto con el Diablo desencadena una numerosa producción literaria así como una abundante plasmación icónica. Nuestra propuesta se focalizará en el desarrollo discursivo imago-textual de la leyenda, especialmente en el proceso de falta, remordimiento y posterior arrepentimiento del protagonista y en la elección de un momento puntual del relato, para relevar los recursos utilizados para manifestar los conceptos fundantes del cristianismo como son el pecado y la redención.
Revisão sistemática das compras públicas sustentáveis entre os anos de 2017 al 2022
Authors: Silva Mineli Kátia Cristina , Loureiro Lourenço Rosenery 
Published: May 2024

As compras sustentáveis no setor público podem beneficiar econômica e social e ambientalmente as instituições e regiões que adotam esses critérios de contratação de serviços e bens. Em face disso há uma ampla revisão da literatura estabelecida em torno de compreender a observância de inserções de políticas públicas e outras regulações no Brasil nas dimensões de sustentabilidade, bem como o comportamento das organizações brasileiras. A partir dos achados em artigos de revisão sobre Compras Públicas Sustentáveis (CPS), o presente artigo buscou compreender os critérios de sustentabilidade discutidos em artigos de revisão sobre CPS e a pertinência das universidades públicas brasileiras nessa discussão. A metodologia empreendida foi a Revisão Sistêmica Integrativa com as 6 etapas propostas por Botelho, Cunha e Macedo (2011). Foram analisados 15 artigos de revisão e os resultados mostram os principais temas discutidos em torno das CPS e os critérios que carecem aprofundamento para que as contratações de bens e serviços contribuam de fato para o desenvolvimento sustentável conforme prescrevem as Leis brasileiras que orientam essas questões.
An epidemiological profile of medico-legal autopsies at a tertiary care center
Authors: Kapil Yadav  , Mustafa khan  , Rajeev Kumar  , Hitesh Chawla  , Tony Jowel  , Renu Yadav  
Published: May 2024

Background: An essential and necessary component of any investigation into a sudden, suspicious death is the medico-legal autopsy. It's critical to understand the profile of medico-legal autopsy cases in order to ascertain the mortality rate from non-natural causes in a given area and addressing the demographic requirements in accordance with the region's unique mortality statistics.
Material & Method: The present study was a retrospective study of autopsies performed at a tertiary care centre in southern Haryana, from January 2018 to December 2023. During this period a total of 886 medico legal autopsies were conducted. Relevant information and subjective data like age, gender, marital status & manner of death have been collected from medico legal autopsy register from January 2018 to December 2023.
Results: It was observed that out of 886 cases male outnumbered females in ratio 2.06:1. Majority of the victims belonged to the age group 21-30 years. Majority of the deaths occurred due to poisoning (n=264, 29.79%), followed by road traffic accidents 26.74%.
Conclusion: Majority of cases were in the 3rd decade of life, males outnumbered females. Poisoning and road traffic accidents were the leading cause of death. Public attention, awareness, preventive and remedial strategies should be undertaken to reduce similar incidents.