bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishing an optimal diagnostic criterion for respiratory sarcopenia using peak expiratory flow rate
Authors: Do Yerim , Lim Youngeun , Kim Jiyoun , Lee Haneul 
Published: May 2024

Abstract
Background
The skeletal muscle changes as aging progresses, causing sarcopenia in the older adult population, which affects the respiratory muscles’ mass, strength, and function. The optimal cut-off point of peak expiratory flow rate (PEFR) for respiratory sarcopenia (RS) diagnosis in accordance with sarcopenia identification is needed.

Aim
To establish an optimal cut-off point of PEFR for RS diagnosis in community-dwelling Asian older women.

Methods
Sarcopenia diagnostic indicators were evaluated according to the Asian Working Group for Sarcopenia 2019 (AWGS) criteria. The respiratory parameters composed of respiratory muscle strength and respiratory function were evaluated by assessing maximal inspiratory pressure (MIP), percent predicted forced vital capacity (Pred FVC), and PEFR.

Results
A total of 325 community-dwelling older women were included in this study. PEFR was negatively associated with RS (OR: 0.440; 95% CI: 0.344–0.564). The area under the curve (AUC) of PEFR was 0.772 (p < 0.001). The optimal cut-off point of PEFR for RS diagnosis was 3.4 l/s (sensitivity, 63.8%; specificity, 77.3%). Significant differences were found between the robust, possible sarcopenia, sarcopenia, and RS groups in terms of both sarcopenia diagnostic indicators and respiratory parameters (p < 0.05).

Conclusions
The cut-off point of PEFR can be used as a reasonable standard for RS diagnosis. This study finding can serve as a cornerstone for developing concrete criteria of RS in older women, supporting clinical judgment, which is crucial for providing appropriate treatment through accurate diagnosis.
Cognitive trajectories preluding the onset of different dementia entities: a descriptive longitudinal study using the NACC database
Authors: Liampas Ioannis , Dimitriou Nefeli , Siokas Vasileios , Messinis Lambros , Nasios Grigorios , Dardiotis Efthimios 
Published: May 2024

Abstract
Objective
To describe the 10-year preclinical cognitive trajectories of older, non-demented individuals towards the onset of the four most prevalent types of dementia, i.e., Alzheimer’s disease(AD), Lewy body(LBD), vascular(VD) and frontotemporal dementia(FTD).

Methods
Our analysis focused on data from older (≥ 60years) NACC (National Alzheimer’s Coordinating Center) participants. Four distinct presymptomatic dementia groups (AD-LBD-VD-FTD) and a comparison group of cognitively unimpaired(CU) participants were formed. Comprehensive cognitive assessments involving verbal episodic memory, semantic verbal fluency, confrontation naming, mental processing speed – attention and executive function – cognitive flexibility were conducted at baseline and on an approximately yearly basis. Descriptive analyses (adjusted general linear models) were performed to determine and compare the yearly cognitive scores of each group throughout the follow-up. Exploratory analyses were conducted to estimate the rates of cognitive decline.

Results
There were 3343 participants who developed AD, 247 LBD, 108 FTD, 155 VD and 3398 composed the CU group. Participants with AD performed worse on episodic memory than those with VD and LBD for about 3 to 4 years prior to dementia onset (the FTD group documented an intermediate course). Presymptomatic verbal fluency and confrontation naming trajectories differentiated quite well between the FTD group and the remaining dementia entities. Participants with incident LBD and VD performed worse than those with AD on executive functions and mental processing speed-attention since about 5 years prior to the onset of dementia, and worse than those with FTD more proximally to the diagnosis of the disorder.

Conclusions
Heterogeneous cognitive trajectories characterize the presymptomatic courses of the most prevalent dementia entities.
The investigation of effect on foot plantar massage on functional recovery in older adults with general surgery, randomized clinical trial
Authors: Saltan Asuman , Mert Selda , Topbaş Önder , Aksu Beyza 
Published: May 2024

Abstract
Objective
Foot massage is known to be effective on the emotional state (anxiety, depression, etc.) in the postoperative period. However, studies on its effect on functional level are insufficient.

Aim
The study aimed to investigate the impact of foot plantar massage on functional recovery in older adults undergoing general surgery, employing a randomized clinical trial design.

Methods
A total of 70 older adults aged 65 years and above who underwent abdominal surgery were included. Various assessments were conducted, including pain levels (Visual Analogue Scale), fear of mobility (Tampa Scale for Kinesiophobia), functional independence (Functional Independence Measure), balance (Berg Balance Scale), basic mobility (Rivermead Mobility Index), mental function status (Standardized Mini-Mental State Examination), and delirium (Nu-DESC).

Results
Statistically significant differences were observed in some assessment parameters within the groups during the 2nd and 3rd measurement times, with the intervention group demonstrating significant mean differences.

Discussions
The literature underscores the increase in kinesiophobia scores post-general/abdominal surgery in older adults, emphasizing the importance of evaluating functional level and kinesiophobia to expedite discharge processes and potentially plan early post-discharge rehabilitation to mitigate readmissions for functional reasons.

Conclusions
Ultimately, foot massage was found to be effective in reducing kinesiophobia, improving balance, mobility, daily living skills, and mental status in older adults post-abdominal surgery, thereby advocating for the facilitation of post-discharge rehabilitation programs or the reduction of readmission rates.

The clinical trials number
NCT05534490.
The Multi-Scalar Inequities of Climate Adaptation Finance: A Critical Review
Authors: Venner Kayin , García-Lamarca Melissa , Olazabal Marta 
Published: May 2024

Abstract
Purpose of Review
Following a multi-scalar analytical approach, this critical literature review explores the factors that determine adaptation finance accessibility and allocation with particular attention to how the needs of climate-vulnerable communities are considered.

Recent Findings
Our review reveals that climate vulnerability is not a primary determinant in the accessibility and allocation of climate adaptation finance at inter-state, sub-national and local scales. Instead, factors such as institutional capacities and financial and political interests exert significant influence. This leads to maladaptation and multi-scalar inequities where climate finance favours relatively resilient groups across scales with less support for more vulnerable populations.

Summary
We argue that finance does not trickle down, but “ripples” within a climate finance arena – where we define the latter as a messy space of competition, negotiation and collaboration. To unlock equitable adaptation finance patterns, future research should focus on the multi-scalar configurations of adaptation finance beyond the international level and consider local and regional territorial and scalar politics.
3D facial animation driven by speech-video dual-modal signals
Authors: Ji Xuejie , Liao Zhouzhou , Dong Lanfang , Tang Yingchao , Li Guoming , Mao Meng 
Published: May 2024

AbstractIn recent years, the applications of digital humans have become increasingly widespread. One of the most challenging core technologies is the generation of highly realistic and automated 3D facial animation that combines facial movements and speech. The single-modal 3D facial animation driven by speech typically ignores the weak correlation between speech and upper facial movements as well as head posture. In contrast, the video-driven approach can perfectly solve the posture problem while obtaining natural expressions. However, mapping 2D facial information to 3D facial information may lead to information loss, which make lip synchronization generated by video-driven methods is not as good as the speech-driven methods trained on 4D facial data. Therefore, this paper proposes a dual-modal generation method that uses speech and video information to generate more natural and vivid 3D facial animation. Specifically, the lip movements related to speech are generated by speech-video information, while speech-uncorrelated postures and expressions are generated solely by video information. The speech-driven module is used to extract speech features, and its output lip animation is then used as the foundation for facial animation. The expression and pose module is used to extract temporal visual features for regressing expression and head posture parameters. We fuse speech and video features to obtain chin posture parameters related to lip movements, and use these parameters to fine-tune the lip animation generated form the speech-driven module. This paper introduces multiple consistency losses to enhance the network’s capability to generate expressions and postures. Experiments conducted on the LRS3, TCD-TIMIT and MEAD datasets show that the proposed method achieves better performance on evaluation metrics such as CER, WER, VER and VWER than the current state-of-the-art methods. In addition, a perceptual user study show that over 77% and 70% of cases believe that this paper’s method is better than the comparative algorithms EMOCA and SPECTRE in terms of realism. In terms of lip synchronization, it received over 79% and 66% of cases support, respectively. Both evaluation methods demonstrate the effectiveness of the proposed method.
Two-Dimensional Materials for Highly Efficient and Stable Perovskite Solar Cells
Authors: Shen Xiangqian , Lin Xuesong , Peng Yong , Zhang Yiqiang , Long Fei , Han Qifeng , Wang Yanbo , Han Liyuan 
Published: May 2024

AbstractPerovskite solar cells (PSCs) offer low costs and high power conversion efficiency. However, the lack of long-term stability, primarily stemming from the interfacial defects and the susceptible metal electrodes, hinders their practical application. In the past few years, two-dimensional (2D) materials (e.g., graphene and its derivatives, transitional metal dichalcogenides, MXenes, and black phosphorus) have been identified as a promising solution to solving these problems because of their dangling bond-free surfaces, layer-dependent electronic band structures, tunable functional groups, and inherent compactness. Here, recent progress of 2D material toward efficient and stable PSCs is summarized, including its role as both interface materials and electrodes. We discuss their beneficial effects on perovskite growth, energy level alignment, defect passivation, as well as blocking external stimulus. In particular, the unique properties of 2D materials to form van der Waals heterojunction at the bottom interface are emphasized. Finally, perspectives on the further development of PSCs using 2D materials are provided, such as designing high-quality van der Waals heterojunction, enhancing the uniformity and coverage of 2D nanosheets, and developing new 2D materials-based electrodes.
Coordinated Control of the Onboard and Wayside Energy Storage System of an Urban Rail Train Based on Rule Mining
Authors: Zhong Zhihong , Mi Jiayu , Zhao Yajie , Yang Zhongping , Lin Fei 
Published: May 2024

AbstractThere are three major challenges to the broad implementation of energy storage systems (ESSs) in urban rail transit: maximizing the absorption of regenerative braking power, enabling online global optimal control, and ensuring algorithm portability. To address these problems, a coordinated control framework between onboard and wayside ESSs is proposed in this study, and the related control strategy is obtained by transforming the global optimization problem into a combination of rule-based and local optimization problems. The design process of the strategy is divided into three parts: offline optimization, rule extraction, and local optimization. First, a genetic algorithm is used to optimize the charge/discharge threshold curves under typical operational conditions. Then, the rules of offline optimization results are obtained from an expert system, and the nonlinear rules are mined with local optimization methods. Finally, a coordinated strategy is presented based on the outcomes of the three parts. A power hardware-in-the-loop (PHIL) experimental platform based on RTLAB is built, and the above coordination strategy is verified based on data for the Beijing Metro Batong Line. The experimental results show that the strategy can effectively improve the energy-saving rate and reduce the regeneration failure rate substantially, with the effect being close to the offline global optimal solution. The algorithm proposed in this paper achieves near global optimal energy-saving optimization results with lower computational costs, and has strong portability, providing a good solution for the large-scale application of onboard and wayside energy storage coordination control.
Molekulargenetik bei „premature ovarian insufficiency“: von der Störung der Follikulogenese bis zur POI
Authors: Rehnitz Julia 
Published: May 2024

ZusammenfassungDie Eizelle und die sie umgebenden somatischen Zellen unterliegen einer komplexen genetischen Regulation während der Follikulogenese. Hierbei ist eine Vielzahl an Genen und Signalwegen zu unterschiedlichen Zeitpunkten aktiv und reguliert die einzelnen Schritte. Die physiologischen Abläufe sind dabei auch zum besseren Verständnis assoziierter Störungen und Erkrankungen relevant. Solche Störungen umfassen unter anderem die eingeschränkte ovarielle Reserve und das schlechte Ansprechen auf eine Stimulationsbehandlung (eine sogenannte „poor response“) bis hin zu einer prämaturen Ovarialinsuffizienz („premature ovarian insufficiency“ [POI]). Die Inzidenzen der Störungen sind äusserst variabel und die Ursachen multifaktoriell. Genetische Ursachen reichen von Einzelfallbeschreibungen von Genvarianten mit sehr seltenem Vorkommen bis zu relativ häufig vorkommenden Faktoren wie der FMR1-Prämutation, FOXL2-Mutationen und dem Turner-Syndrom. Diese sind auch aufgrund ihrer möglichen Folgen nicht nur für die Patientinnen selbst, sondern auch für ihre Verwandten bei der klinischen Diagnostik einer POI von erhöhtem Interesse.
High temperature infiltration behavior and reaction characteristics of Colima volcanic ashes on gadolinium zirconate coatings deposited by atmospheric plasma spraying
Authors: Bedoya-Trujillo Ivan F. , Gutiérrez-Pérez Aixa I. , Pérez Sebastián , Brizuela-Colmenares Natalia , Zárate-Medina Juan , Muñoz-Saldaña Juan 
Published: May 2024

AbstractVolcanic ashes are considered a serious threat to the aircraft industry. At high temperatures, they inflict severe thermochemical damage to the typical 7 wt.% yttria-stabilized zirconia thermal barrier coatings that protect the aircraft turbine. There is a need to evaluate alternative materials with excellent resistance to infiltration of molten siliceous particles, such as gadolinium zirconate. In this work, free-standing thermal barrier coatings of gadolinium zirconate were manufactured by atmospheric plasma spraying, varying deposit parameters to obtain different relative densities to evaluate the infiltration of molten Colima volcanic ashes for 1 h and 10 h at 1250 °C. The infiltration depth and the reaction products resulting from each interaction, were studied by different characterization techniques. In general, the coatings show high resistance to the infiltration of the volcanic ashes, reaching infiltration depths between 50 µm and 80 µm after 10 h of infiltration time. In this sense, gadolinium zirconate coatings are excellent candidates against the infiltration of Colima volcanic ashes compared to the typical yttria-stabilized zirconia-based thermal barrier coatings.
Germination characteristics of Sorghum bicolor (L.) Moench. under different pH regimes after chemo-priming
Authors: Onoabhagbe Osemudiamen , Ogwu Matthew Chidozie , Ikhajiagbe Beckley 
Published: May 2024

AbstractSoil pH not only plays a regulatory role in seed germination but also influences seedling development, flowering, and crop yield. The study investigated the germination characteristics of sorghum [Sorghum bicolor (L.) Moench.] under varying pH to understand the potential ameliorative effects of seed priming using plant growth-promoting substances. Seeds were sown in Petri dishes with pH moistened solutions at 1, 3, 5, 7, 9, 11, and 13 respectively. These were replicated five times in the second stage, viable seeds were first primed in 150 ppm indole-3-acetic acid, gibberellic acid, and vitamin C before sowing in pH solutions. The experiment showed no significant changes in morphology or physiology of primed and unprimed seeds and no germination at extreme pH. However, there was a significant difference in the activity of enzymes, germination time, and speed as well as germination percentages of both primed and unprimed seeds. Although chemo-priming did not reverse the effect of pH, it was observed however that vitamin C had a significant effect on germination percentage at higher pH. Germination was observed to be impaired at extreme pH. Seeds did not respond to germination capacity suggesting an optimal pH range of 3 and 11 for germination without priming. However, priming did not show any improved germinability index. Seeds primed in the presence of light showed enhanced germination at pH 7. Generally, the germination index without priming showed better germination characteristics than primed seeds, which suggests pH interactions with primers may be a limiting factor.
Genome editing toward biofortified soybean with minimal trade-off between low phytic acid and yield
Authors: Lin Wenxin , Bai Mengyan , Peng Chunyan , Kuang Huaqin , Kong Fanjiang , Guan Yuefeng 
Published: May 2024

AbstractPhytic acid (PA) in grain seeds reduces the bioavailability of nutrient elements in monogastric animals, and an important objective for crop seed biofortification is to decrease the seed PA content. Here, we employed CRISPR/Cas9 to generate a PA mutant population targeting PA biosynthesis and transport genes, including two multi-drug-resistant protein 5 (MRP5) and three inositol pentose-phosphate kinases (IPK1). We characterized a variety of lines containing mutations on multiple IPK and MRP5 genes. The seed PA was more significantly decreased in higher-order mutant lines with multiplex mutations. However, such mutants also exhibited poor agronomic performance. In the population, we identified two lines carrying single mutations in ipk1b and ipk1c, respectively. These mutants exhibited moderately reduced PA content, and regular agronomic performance compared to the wild type. Our study indicates that moderately decreasing PA by targeting single GmIPK1 genes, rather than multiplex mutagenesis toward ultra-low PA, is an optimal strategy for low-PA soybean with a minimal trade-off in yield performance.
Incidental dural tears during pediatric posterior spinal fusions
Authors: Nilssen Paal K. , Compton Edward , Stephan Stephen , Andras Lindsay M. , Chu Jason K. , Skaggs David L. , Illingworth Kenneth D. 
Published: May 2024

Abstract
Purpose
To characterize the frequency of incidental dural tears in pediatric spine surgery, their treatment, complications, and results of long-term follow-up.

Methods
A retrospective review of all pediatric patients who underwent a posterior spinal fusion (PSF) between 2004–2019 at a tertiary children’s hospital was conducted. Electronic medical records were reviewed for patient demographics, intra-operative data, presence of an incidental dural tear, repair method, and patient outcomes.

Results
3043 PSFs were reviewed, with 99 dural tears identified in 94 patients (3.3% overall incidence). Mean follow-up was 35.7 months (range 0.1–142.5). When the cause of the dural tear was specified, 69% occurred during exposure, 5% during pedicle screw placement, 4% during osteotomy, 2% during removal of implants, and 2% during intra-thecal injection of morphine. The rate of dural tears during primary PSF was significantly lower than during revision PSF procedures (2.6% vs. 6.2%, p < 0.05). 86.9% of dural tears were repaired and/or sealed intraoperatively, while 13.1% had spontaneous resolution. Postoperative headaches developed in 13.1% of patients and resolved at a mean of 7.6 days. There was no difference in the incidence of headaches in patients that were ordered bedrest vs. no bedrest (p > 0.99). Postoperative infections occurred in 9.5% of patients and 24.1% patients were identified to have undergone a revision surgery.

Conclusions
Incidence of intra-operative dural tears in pediatric spine surgery is 3.3%. Although complications associated with the dural tear occur, most resolve over time and there were no long-term sequelae in patients with 2 years of follow up.

Level of evidence
Level IV.
Explaining research performance: investigating the importance of motivation
Authors: Svartefoss Silje Marie , Jungblut Jens , Aksnes Dag W. , Kolltveit Kristoffer , van Leeuwen Thed 
Published: May 2024

AbstractIn this article, we study the motivation and performance of researchers. More specifically, we investigate what motivates researchers across different research fields and countries and how this motivation influences their research performance. The basis for our study is a large-N survey of economists, cardiologists, and physicists in Denmark, Norway, Sweden, the Netherlands, and the UK. The analysis shows that researchers are primarily motivated by scientific curiosity and practical application and less so by career considerations. There are limited differences across fields and countries, suggesting that the mix of motivational aspects has a common academic core less influenced by disciplinary standards or different national environments. Linking motivational factors to research performance, through bibliometric data on publication productivity and citation impact, our data show that those driven by practical application aspects of motivation have a higher probability for high productivity. Being driven by career considerations also increases productivity but only to a certain extent before it starts having a detrimental effect.
Towards a Circular Solar Power Sector: Experience with a Support Framework for Business Model Innovation
Authors: Strupeit Lars , Bocken Nancy , Van Opstal Wim 
Published: May 2024

AbstractThe rapid expansion of the global solar photovoltaic (PV) market as part of the transition to a low-carbon energy future will increase both demand for raw materials used in PV product manufacturing as well as future PV panel waste volumes. There is an urgent need for solar industry businesses to adopt circular business models, and to support this process through targeted tools and methods that can facilitate the innovation process of such models. This paper employs an action-oriented case study methodology, drawing on insights garnered from five demonstrator cases that have applied and validated a Circular Business Model Innovation (CBMI) framework within the PV sector. Results show how this framework was applied in practice during the ideation, design, experimentation, and scaling phases of the innovation process. Specifically, results show how an experimental and iterative approach was found critical to assess viability, desirability, and feasibility of circular business strategies. The study’s empirical testing of tools with the context of a Circular Economy complements earlier theoretical conceptualizations of business model innovation processes. It illustrates how using multiple tools can provide firms with complementary insights in each stage of ideation, design, testing, and scaling of business models. It is recommended that policy makers and business leaders endorse such co-creative and experimental approaches to foster learning and business model innovation, thereby catalysing the transformation of an entire renewable energy industry sector towards Circular Economy.