bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survei Nervuos Atlet Tenis Meja Ptm Ije-Jela Kab.Barito Kuala Saat Bertanding
Authors: Rifqi Irvannoor  , Kahri Ma’ruful , Rahmadi  
Published: June 2024

Pada dasarnya nervous sangat perpengaruh pada pertandingan atlet tersebut, nervous menyebabkan performa atlet tidak maksimal. Maka dari itu artikel ini bertujuan untuk mengenal nervous pada atlet saat bertanding dan untuk memberi pemahamaan mendalam bentuk berbagai tekanan mental yang di alami atlet tenis meja. Manfaat dari penelitian ini ialah untuk mengetahui bentuk nervous apa saja yang pling sering di rasakan oleh atlet tenis meja saat bertanding. responden yang di teliti adalah atlet PTM Ije-jela Kab. Barito Kuala yang berjumlah 20 responden yamg terdiri dari 10 laki-laki dan 10 perempuan. Penelitian ini mengunakan kuisioner yang di bikin melalui google form yang di kirim melalui whatshaap, kemudian di isi oleh responden. Teknik yang di gunakan dalam penelitian ini adalah one survey, yang di maksud dengan one surey ialah penelitian yang di lakukan dalam sekali pengambilan data. Pengolahan data penelitian ini mengunakan excel untuk mendapatkan hasil penelitian. Berdasarkan penelitian ini atlet tenis meja PTM ije-jela Kab.Barito Kuala pengaruh faktor eksternal sebesar 63 % berada di kategori sedang. Kesimpulan dari penelitian ini ialah faktor Tingkat tekanan mental yang sering di rasakan oleh atlet tenis meja PTM ije-jela Kab.Barito Kuala adalah faktor internal sebesar 70,3 % barada di kategori tinggi. Kesimpulan dari hasil penelitian ini adalah faktor yang paling mempengaruhi Tingkat nervous pada atlet PTM ije-jela Kab.Barito Kuala adalah faktor internal sebesar 70,3 % berada di kategori tinggi.
Pengaruh Self Compassion Terhadap Kondisi Fisik Atlet Bulutangkis
Authors: Hafizt Faishal , Encep Sudirjo  , Aam Ali Rahman  
Published: June 2024

Tujuan dalam penelitian ini yaitu untuk mengetahui pengaruh self compassion terhadap kondisi fisik atlet bulutangkis. Metode penelitian yang digunakan adalah metode kuantitatif dengan jenis penelitian korelasional. Populasi dalam penelitian ini yaitu atlet bulutangkis se-kecamatan jatiwangi, teknik pengambilan sampling yang digunakan dalam penelitian ini menggunakan purposive sampling dengan keriteria atlet berusia 8 – 12 tahun sebanyak 35 atlet. Teknik pengumpulan data dalam penelitian ini adalah menggunakan kuesioner self compassion dan tes kondisi fisik untuk mengetahui jawaban dari sampel dan hasil dari tes kondisi fisik. Hasil analisis data secara statistik dibantu oleh aplikasi SPSS21dengan melakukan uji Normalitas diperoleh nilai didapatkan hasil kuesioner self compassion sebesar 0,237 > 0,05 dan hasil kondisi fisik sebesar 0,136 > 0,05 sehingga data berdistribusi normal, kemudian uji linearitas diperoleh hasil 0,562 > dari 0,05 sehingga dinyatakan linear atau sejalan karena hasil dari signifikan, selanjutnya uji pearson product moment diperoleh hasil sig. (2 - tailed) 0,040 > 0,05 dan R tabel 0,334 > 0,05 maka dapat disimpulkan ada hubungan secara signifikan. Hal ini menunjukkan bahwa setelah sampel mengisi kuisioner dan melakukan tes kondisi fisik pada cabang olahraga bulutangkis, maka hasil dari variabel self compassion terhadap kondisi fisik atlet bulutangkis memiliki pengaruh secara signifikan sebesar 0,040.
Transforming Indonesian Washing Machines into Efficient Wind Generators
Authors: Putra Ahmad Nurwanda Bawono , Firdaus Rachmat 
Published: June 2024

People's consumption of household electronic devices is increasing, leading to higher energy demand in Indonesia, with washing machines being a significant contributor. This study explores repurposing used washing machine dynamos into electricity generators for windmills. Researchers used an LG washing machine dynamo and N52 neo super magnets, testing pulley diameters of 12 cm, 15 cm, 18 cm, and 20 cm. Results showed that larger pulleys increased generator output, with a 20 cm pulley producing 26 volts, 1.3 amperes, and 2525 rpm. However, the efficiency was low at 8.69%, indicating a need for further optimization. This approach has potential for sustainable energy solutions and reducing electronic waste.

Highlight:

Repurpose Dynamos: Converts washing machines to windmill generators, reducing electronic waste.
Efficiency Challenge: Larger pulleys improve output but efficiency is only 8.69%.
Sustainable Impact: Offers potential for sustainable energy and lower household consumption.

Keyword: household electronics, energy consumption, washing machine dynamo, windmill generator, sustainable energy
HIGHLY BIOERODED RHODOLITHS FROM THE VITÓRIA-TRINDADE SEAMOUNT CHAIN (BRAZIL, SOUTHWESTERN ATLANTIC)
Authors: FRANCO TARCILA , BASTOS ALEX CARDOSO , BASSI DAVIDE , BRAGA JUAN CARLOS 
Published: June 2024

Abstract
Rhodoliths are nodules mainly composed of crustose coralline algae with subordinate encrusting organisms, formed by successive overlapping encrustation. The subspheroidal rhodoliths from the Vitória-Trindade Seamount Chain (Jaseur Seamount and Trindade Island shelf; Brazil, southwestern Atlantic), sampled at water depths from 65 to 74 m, were built by crustose coralline algae (Harveylithon, Lithophyllum, Lithothamnion, Mesophyllum, Roseolithon, and Sporolithon) and subordinated encrusting foraminifera (agglutinated, unidentified hyaline, and Homotrema rubrum), bryozoans, serpulids, and balanids. Successive taphonomic phases of bioerosion, boring filling, and cement precipitation modified the original rhodolith inner structures resulting in a complex structureless mass of coralline algal fragments, encrusting organisms, borings, lithified fine-grained sediment, and carbonate cement. Borings include the ichnogenera Entobia (produced by etching sponges), Gastrochaenolites (boring bivalves) and Trypanites (polychaetes and sipunculid worms). The lithification of the material filling the borings (micrite and carbonate cements) created new substrates for subsequent bioerosion. Radiocarbon dating of selectively sampled invertebrate and algal skeletons in the rhodolith interior yielded calibrated ages of hundreds of years (up to 912 ± 152 years cal. BP on the Trindade insular shelf and up to 763 ± 131 years cal. BP on Jaseur Seamount). These values indicate growth rates from 0.1 to 0.5 mm/year, which are significantly higher than those recorded from rhodoliths at similar depths on the Brazilian shelf. Low sedimentation settings and high productivity at the tops of the seamounts and island shelf promoted the growth of nodule frame builders, both autotrophs and heterotrophs, and favored continuous activity of bioeroders.
Not a cluster of grapes, but bananas: Cord-like three-dimensional structure of cysts in ADPKD supports tubular obstruction hypothesis
Authors: Han Shuai , Yang Ming , Song Haihan , Cheng Ming , Chen Shunjie , Mei Changlin , Yang Xiu 
Published: June 2024

Abstract

We investigated the three-dimensional structure of the kidneys of mouse models of autosomal dominant polycystic kidney disease (ADPKD), a progressive genetic kidney disease and one of the leading causes of end-stage renal disease. We performed histological observations and transparentized the kidneys for three-dimensional imaging on rapid-onset and chronic-onset models. We found that the cysts had a cord-like structure resembling a cluster of bananas rather than a bunch of grapes, suggesting tubular obstruction as the initiating event. We also detected epithelial cell bridges within the renal tubules, which could be the cause of the obstruction. We compared the cell proliferation of kidney tissue at different developmental stages with wild type mice, and found no significant difference, indicating that there was no additional cell proliferation. Our findings support the obstruction hypothesis and challenge the proliferation hypothesis for ADPKD, and may provide new insights for finding potential treatments.
Immobilization of L-Asparaginase on Biofunctionalized Magnetic Graphene Oxide Nanocomposite: A Promising Approach for Enhanced Stability and Reusability
Authors: monajati maryam , Ariafar Nasim , Abedi Mehdi , Borandeh Sedigheh , Tamaddon Ali Mohammad 
Published: June 2024

Abstract

The application of the amidohydrolase enzyme, L-asparaginase (ASNase), as a biocatalyst in the food and pharmaceutical industries has garnered significant interest. However, challenges such as hypersensitivity reactions, limited stability, and reusability under various operational conditions have hindered its cost-effective utilization. This paper introduces a novel nano-support for ASNase immobilization, namely the nanocomposite of iron oxide magnetic nanoparticles and amino acid-decorated graphene oxide (GO-Asp-Fe3O4). Characterization using FTIR spectroscopy, FE-SEM, and TEM microscopy revealed the homogeneous distribution of iron oxide nanoparticles on the surface of GO sheets. The effects of carrier functionalization and carrier-to-protein ratio on the immobilization of ASNase were studied to optimize the immobilization conditions. The magnetized nanocomposite of ASNase exhibited a 4.4-fold lower Michaelis-Menten constant (Km), suggesting an enhanced affinity for the substrate. The immobilized ASNase demonstrated two to eight times higher thermostability compared to the free enzyme and showed an extremely extended pH stability range. Furthermore, the immobilized enzyme retained over 80% of its initial bioactivity after eight repeated reaction cycles. These findings suggest that the immobilization of ASNase on GO-Asp- Fe3O4 nanocomposite could be a viable option for industrial applications.
Burden of Non-prescribed drug use and its associated factors among Pregnant Women in Peri-urban kebeles’ of Jimma town, southwest Ethiopia, 2023
Authors: Yene Fentahun , Bantie Berihun , Yilma Tarekegn , Zinab Idalamin , Animen Simachew 
Published: June 2024

Abstract

Background: Non-prescribed drug utilization is the act of using medication to treat self-diagnosed problems without consulting a healthcare provider. Pregnant women are among the most vulnerable population groups for self-medication to treat pregnancy-related problems. The use of non-prescribed drugs, however, has numerous detrimental effects on both the growing fetus and the mother. Besides, community-based information regarding the pattern of non-prescribed drug use is limited in Ethiopia. Hence, this study aims to investigate non-prescribed drug use and its associated factors among pregnant women in Jimma town, southwest Ethiopia, in 2023.
Method and Materials: A community-based cross-sectional study was conducted among 358 pregnant mothers in the peri-urban kebeles of Jimma town, southwest Ethiopia. A systematic random sampling technique (every K = 3 households) was used to select the final study participants. Data were collected using an interviewer-administered structured questionnaire, entered into EpiData version 7.2.2 software, and exported to SPSS version 25 for further analysis. Both bivariable and multivariable logistic regression models were fitted to identify the factors influencing non-prescribed drug utilization status. The level of significance of the association was determined at a P-value < 0.05 with a 95% CI.
Result: Overall, the prevalence of non-prescribed drug use among pregnant mothers was 37.7% (95% CI: 32.8–41.7%). Enrollment in health insurance (AOR = 0.21, 95% CI: 0.03–0.76), being primigravida (AOR = 3.05, 95% CI: 1.03–5.08), and experiencing any pregnancy-related complications (AOR = 2.34, 95% CI: 1.99–2.76) were found to be significant factors affecting the non-prescribed drug utilization status of pregnant mothers.
Conclusion and recommendations: In the current study, non-prescribed drug use among pregnant mothers was high. Health insurance enrollment status, gravidity, and the presence of any pregnancy-related complications were identified as significant predictors of non-prescribed drug use among pregnant mothers. Hence, stakeholders should invest their efforts in increasing community enrollment in health insurance programs and place special emphasis on high-risk groups prone to non-prescribed drug use.
Angiogenesis and endometrial receptivity in the decidua of cesarean scar pregnancies
Authors: Liu Yu , Ma Xixiang , Du Xin , Jin Jing , Cui Yizhen , Zhou Jianshan , Song Guanglin , Li Huiman , Lei Yan 
Published: June 2024

Abstract

Background
Cesarean scar pregnancy (CSP) is defined as a gestational sac or trophoblast implanted within the previous cesarean scar (CS). The study aimed to investigate the mechanism of CSP.
Methods
We collected the decidua tissues of CSP patients from cesarean scar (n = 25) or uterine cavity of the same women (n = 25) at department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology from July to December 2023. Morphological changes and angiogenesis in the decidua tissues were examined. And we studied the expression of the factors related to endometrial recovery. Scanning electron microscope was used to detect the number of pinopodes.
Results
The decidua tissues in the CSP-uterine scar group have more diffuse lymphocyte infiltration compared to CSP-cesarean cavity group. The vessel density (31.95 vessels/mm2) was significantly decreased in CSP-uterine scar group compared to CSP-cesarean cavity group (69.4 vessels/mm2, P<0.01). The vascular surface (0.0180 ± 0.0018 mm2/mm2) and luminal surface (1,871.00 ± 352.65 m2/vessel) was significantly smaller in CSP-uterine scar group compared to CSP-cesarean cavity group (0.0550 ± 0.0031 mm2/mm2 and 2,930.00 ± 548.14 m2/vessel, P<0.01). Compared to CSP-cesarean cavity group (7.00 ± 1.00), the number of pinopodes in CSP-uterine scar group were significantly decreased (0.33 ± 0.58). The expression of CD56, IL-6 and IL-1βin CSP-uterine scar group were significantly lower than those in CSP-cesarean cavity group.
Conclusions
There were lower angiogenesis and endometrial receptivity in cesarean scar decidua tissuess. The changes in the vascular pattern of cesarean scar decidua tissues may be beneficial for embryo implantation.
HMGB1 as a Biomarker for Myeloproliferative Neoplasm Complicated with Atherosclerosis
Authors: Wu Lunbi , Han Dongxue , Zhang Xiaodong , Zhang Shixu , Wang Yicong , Han Wenxue , Jiang Bowen , Chen Huailei , Jiang Libo 
Published: June 2024

Abstract

Objective
The study analyzed the correlation between levels of HMGB1 in patient's serum and biochemical indices related to atherosclerosis, clarifying the diagnostic value of HMGB1 in myeloproliferative neoplasm (MPN) complicated with atherosclerosis (AS).
Methods
Bone marrow and serum of MPN patients were collected; qPCR was used to detect the level of HMGN1 mRNA in bone marrow mononuclear cells; ELISA was used to measure the level of HMGB1 in serum. Relevant biochemical indices of the patients were also collected, and the correlation between these indices and HMGB1 was analyzed.
Results
Compared with the control group, the levels of HMGB1 in both bone marrow mononuclear cells and serum of MPN patients were significantly higher; Pearson correlation analysis showed that the level of HMGB1 in serum was negatively correlated with HDL-C and ApoA1; ROC curve showed that the AUC of serum HMGB1 in predicting AS complication in MPN was 0.929 (P < 0.001), with a sensitivity of 100.00% and a specificity of 78.05%; Logistic regression analysis showed that the level of HMGB1 in serum has statistical significance with whether the MPN patient has AS (P < 0.05).
Conclusion
The raised levels of HMGB1 in the bone marrow and serum of MPN patients show correlation with biochemical indices related to AS, which may provide reference for predicting AS complication in MPN patients.
Osimertinib plus Chemotherapy versus Osimertinib for Patients with Advanced NSCLC Concomitant EGFR and TP53 Mutations: A Prospective Cohort Study
Authors: Li Jixian , Zhan Xiang , Shao Mengqing , Zeng Renya , Li Jianan , Zhu Hui , Feng Alei , Yang Zhe , Jing Wang 
Published: June 2024

Abstract

Background
Osimertinib is the standard first-line options for patients with advanced EGFR-mutated non-small cell lung cancer (NSCLC). Co-mutations in TP53 results in poor survival for patients. However, the studies on treatment options and clinical outcomes of patients with EGFR-TP53 co- mutation are limited.
Methods
Patients with EGFR mutation-positive locally advanced or metastatic NSCLC carrying TP53 mutations were recruited from two institutions and allocated into two groups, either receiving osimertinib plus chemotherapy (Osi + Chemo group) or osimertinib monotherapy (Osi group). The progression-free survival (PFS) was evaluated as the primary endpoint and the response was also assessed.
Results
Between January 2020 and August 2023, Ninety-eight patients were enrolled with 47 and 51 patients receiving combination therapy and the monotherapy. After a median follow-up of 19.2 months, overall response rate (ORR) was 80.0% versus 71.7% (p = 0.36), favoring Osi + Chemo group, as well as in disease control rate (DCR) (91.4% vs. 80.4%, p = 0.45). The median PFS in the Osi + Chemo group was 26.0 months versus 20.7 months in the Osi group, but without significant difference (p = 0.34). The subgroup analysis indicated that for patients with L858R mutation, Osi + Chemo therapy significantly prolonged the median PFS (not reached [NR] versus 17.1 months, p = 0.03), but not in patients with 19Del (20.6 months versus NR, p = 0.31).
Conclusion
Osimertinib plus chemotherapy have a tendency to increase ORR and prolong PFS in NSCLC with EGFR and TP53 co-mutations, particularly in patients with L858R mutation.
Exchange Rate Regime Choices and Real Effective Exchange Rate Misalignments: Degree and Persistence
Authors: Byusa Vincent , Byusa Vincent 
Published: June 2024

Abstract

This paper assesses the impact of de facto exchange rate regime (ERR) choices on the magnitude and the persistence of multilateral price levels-based (also known as real effective exchange rate, REER) misalignments in a large sample of countries (126) over the period 1990–2019. This paper considers the random effects within-between (REWB) framework to evaluate the degree of REER misalignments and the novel mean-group instrumental variables (MGIV) to estimate the persistence of the REER misalignments. This paper finds that both fixed and intermediate ERRs perform better in limiting the degree of REER misalignment than the floating ERRs Furthermore, this paper finds evidence of the strongest persistence of REER misalignment in the fixed and intermediate ERRs. These results indicate that the choice of ERR is relevant to REER misalignment.
JEL codes: C33, F32, F31, F33, F41
Choriocarcinoma metastases complicated with cerebral venous sinus thrombosis in the third trimester of pregnancy: a case report and literature review
Authors: Wang Sheng , Wang Changrong , You Feng 
Published: June 2024

Abstract

Background Intracerebral hemorrhage (ICH) in younger females is usually attributed to ruptured aneurysms or cerebrovascular malformations. By contrast, metastatic brain tumors and complications stemming from intracranial venous sinus thrombosis (CVST)-associated hemorrhagic strokes are rare instigators of ICH in women of childbearing age. We report a case of choriocarcinoma metastasis with rapid progression of cerebral venous sinus thrombosis in a patient in the third trimester. Additionally, the literature review revealed only two cases where choriocarcinoma was complicated by CVST, and both were identified post-chemotherapy.
Case presentation A case of a 33-year-old expectant woman, in her 32+ weeks of pregnancy, sought hospital admission owing to persistent blurred vision that had prevailed for over half a month. After her admission, she endured three instances of ICH within only one week, during which period digital subtraction angiography unveiled the presence of thrombosis within the superior sagittal sinus. Choriocarcinoma in the third trimester with lung and brain metastases, ICH, and CVST. The patient underwent an emergency caesarean section and delivered a premature baby girl. Catheter directed thrombolysis in the intracranial venous sinus and evacuation of the hematoma by craniotomy were subsequently performed. Eventually, this patient was diagnosed with choriocarcinoma with multiple metastases and received drug chemotherapy.
Conclusions The symptoms and imaging findings of brain metastases with hemorrhage and CVST overlap with each other, resulting in delaying and confusing the diagnosis. Furthermore, early diagnostic interventions for choriocarcinoma coupled with intensive treatment strategies can potentially improve patient prognosis and help avoid life-threatening consequences.
Exploring the Relationship Between Land Use and Pesticide Contamination in a Tropical Rural Catchment: A Case Study of River Chanchaga
Authors: Ikayaja Eunice O. , Tshimanga Raphael M. , Ndatimana Gilbert , Zabbey Nenibarini , Arimoro Francis O. 
Published: June 2024

Abstract

Freshwater ecosystems are vulnerable to various land uses, resulting in concern for aquatic organisms and humans. Understanding the occurrence of pesticide contamination is necessary to safeguard aquatic biodiversity and human health. Against this background, our study aimed to assess the effect of various land uses on pesticide contamination by evaluating three selected sites according to land use class: a control site (CON), an agricultural area (S1), and an urban area (S2). Various classes of land use around the catchment were determined using ArcGIS 10.8 GIS software, while analysis of pesticide residues was carried out using the liquid-liquid extraction method, followed by gas chromatography-mass spectrometry (GC/MS). A total of 10 herbicides and 12 insecticides were recorded in each sampled sub-catchment, with a statistically significant difference across the sampled sub-catchment. Sampled sites located in agricultural and urban areas recorded higher concentrations of pesticide residues compared to sites located in natural areas, with less anthropogenic influence, reflecting differences in pesticide usage. Redundancy analysis (RDA) revealed crops and urbanized land use were the main sources of pesticide contamination in the water, as pesticides are predominantly used on farms and in various households. Their presence in the water may have potentially detrimental effects on aquatic biodiversity because pesticides have been associated with various health issues. It was evident that all sampled sub-catchments had pesticide concentrations exceeding the WHO permissible limit for human consumption. Implementing alternative methods for managing pests and weeds without relying on pesticides is crucial for sustainable agriculture and environmental preservation.
A Blockchain Auto-Scaling Node Organizing Design Model for the Internet of Things
Authors: ELSAADANY Riham , Bégin Guy 
Published: June 2024

Abstract

Many node-organizing blockchain models for IoT lack the scalability needed for high transaction volumes and mechanisms to manage decentralization and node overhead. This study proposes a multi-tiered Self-Scalable Dynamic architecture based on a forest of trees to improve scalability and efficiency by clustering all nodes to limit those involved in consensus. In addition to the architecture, our contributions include: i) A protocol to speed up consensus. ii) A mechanism for efficient node-lookup and message-routing. iii) A dynamic algorithm to balance overhead and decentralization. iv) A colocality mechanism to enhance consensus time. This architecture reduces consensus time with an upper bound of O(1) plus a propagation delay factor. As more IoT devices join, resulting in a deeper forest, the model becomes more scalable with shorter consensus delays. The proposed mechanisms may serve as general-purpose solutions for scalability, load balancing, node-lookup and message-routing, and are application-, clustering-, and consensus-algorithm-agnostic.