bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nutrition and physical activity guidelines for cancer survivors
Authors: Rock Cheryl L. , Doyle Colleen , Demark‐Wahnefried Wendy , Meyerhardt Jeffrey , Courneya Kerry S. , Schwartz Anna L. , Bandera Elisa V. , Hamilton Kathryn K. , Grant Barbara , McCullough Marji , Byers Tim , Gansler Ted 
Published: April 2012

AbstractAnswer questions and earn CME/CNECancer survivors are often highly motivated to seek information about food choices, physical activity, and dietary supplements to improve their treatment outcomes, quality of life, and overall survival. To address these concerns, the American Cancer Society (ACS) convened a group of experts in nutrition, physical activity, and cancer survivorship to evaluate the scientific evidence and best clinical practices related to optimal nutrition and physical activity after the diagnosis of cancer. This report summarizes their findings and is intended to present health care providers with the best possible information with which to help cancer survivors and their families make informed choices related to nutrition and physical activity. The report discusses nutrition and physical activity guidelines during the continuum of cancer care, briefly highlighting important issues during cancer treatment and for patients with advanced cancer, but focusing largely on the needs of the population of individuals who are disease free or who have stable disease following their recovery from treatment. It also discusses select nutrition and physical activity issues such as body weight, food choices, food safety, and dietary supplements; issues related to selected cancer sites; and common questions about diet, physical activity, and cancer survivorship. CA Cancer J Clin 2012. © 2012 American Cancer Society.
La production des enquêtes quantitatives
Authors: Caveng Rémy 
Published: April 2012

Dans la littérature consacrée à la qualité des enquêtes quantitatives et dans les arguments de vente des entreprises de sondage, la standardisation du recueil de données ainsi que la réduction de « l’effet enquêteur » tiennent une place centrale. Pour atteindre ces deux objectifs, il suffirait d’appliquer à la lettre un ensemble de règles. Or la réalité du terrain est bien éloignée de ces standards de production et les enquêteurs aménagent systématiquement le protocole de passation. Plusieurs raisons permettent d’en rendre compte : la passation d’un questionnaire, comme toute interaction sociale, ne saurait être purement standard ; le niveau de productivité attendu contrevient à la réalisation du travail tel qu’il est prescrit ; les conditions d’emploi, de travail et de rémunération des enquêteurs ne les incitent pas à se conformer à ces prescriptions. Une conception réaliste et pragmatique de la qualité des données impliquerait alors de prendre en compte ces trois dimensions.
La construction locale d’une base transnationale de données en botanique
Authors: Heaton Lorna , Proulx Serge 
Published: April 2012

Cet article décrit le travail d’une équipe de cinq personnes se consacrant à la numérisation de spécimens de plantes contenus dans un vaste herbier à Montpellier, projet ayant pour objectif la production de données numériques devant être insérées dans une banque de données d’envergure mondiale. Notre analyse descriptive met en lumière, d’une part, l’invisibilité associée aux contraintes d’une infrastructure informationnelle transnationale qui sépare les données de leur lieu de production locale : le travail de ces personnes constitue un travail fantôme, un travail de « petites mains », un travail rendu invisible du fait de l’envergure mondiale du projet qui suppose une standardisation des tâches d’exécution et l’anonymat des exécutants. D’autre part, nous nous interrogeons sur l’importance des valeurs politiques et morales associées à la configuration d’un dispositif sociotechnique cherchant à valoriser à la fois la production scientifique et les individus qui en sont responsables. Enfin, le cas présenté ici donne à voir la transposition en mode numérique de données scientifiques déjà existantes. Cette transformation matérielle restreint certaines possibilités de production des savoirs tout en ouvrant la porte à de nouveaux possibles cognitifs.
La chambre froide
Authors: Yi Mi-Kyung 
Published: April 2012

Résumé La frigidité féminine est comme l’impuissance masculine, mais en « plus bruyante ». Cette affirmation laconique de Freud témoigne de la perplexité que suscite ce trouble dans la théorie comme dans la pratique. À la fois, évidence et énigme. En effet, l’émergence de la question de la frigidité ne se produit jamais sans faire des histoires , sans ouvrir des questions jusque-là confinées dans l’ombre, comme celle de la passivité. L’auteur propose de cerner ce pouvoir d’interrogation de la frigidité féminine, tel qu’il se révèle dans l’histoire de la sexualité et la théorie psychanalytique, tout comme dans la cure psychanalytique.
L'inhibition psychosexuelle
Authors: Lepastier Samuel 
Published: April 2012

Résumé Dans cet article, l’auteur, plutôt que de dresser une liste des symptômes faisant obstacle à une vie sexuelle heureuse, préfère considérer que ceux-ci sont des expressions différenciées au sein d’un continuum commun : l’inhibition psychosexuelle. Celle-ci se manifeste aussi bien par des limitations du plaisir amoureux que par des difficultés à maintenir un lien privilégié avec l’objet élu. Dans cette perspective, il apparaît vain de prôner la recherche du plaisir par des recettes mécaniques.
What is this thing called love ?
Authors: Denis Anne 
Published: April 2012

Résumé La vie amoureuse, qui suppose « la totalité » de la force pulsionnelle, dépend de la levée du clivage du moi, qui peut être traumatique : le passage à la génitalité adulte avec l’abandon du primat du phallus et la perte des limites narcissiques provoquent une déstructuration de l’appareil psychique. « Plaisir négatif », comme tous les plaisirs élevés, l’état amoureux et sa réalisation orgastique sont apparentés au sentiment océanique par les poètes qui y voient une « connaissance » dont le modèle peut servir à la communication des esprits.
Le tabou de la frigidité. Le silence des alcôves
Authors: Schaeffer Jacqueline 
Published: April 2012

Résumé Au-delà des pathologies avérées, les angoisses et les troubles de la sexualité peuvent être explorés au niveau de la pratique de la vie sexuelle ordinaire, tout autant que par les fantasmes et le transfert. La sexualité adulte n’est pas l’objet de l’intérêt des psychanalystes au même titre que la sexualité infantile et le réveil du deuxième temps du diphasisme à l’adolescence. Cependant, ce qui peut être dit dans la cure de la sexualité effective est révélateur de la profondeur de la vie psychique, des fantasmes sexuels et bisexuels inconscients, de l’élaboration de la différence des sexes et de la relation à l’objet. La frigidité n’est-elle que féminine, et l’impuissance uniquement masculine ?
Un premier amour ne s'oublie jamais (ou presque)
Authors: Balsamo Maurizio 
Published: April 2012

Résumé La clinique borderline montre une « indésirable » fidélité à l’objet primaire, de sorte que le problème pourrait être : comment passer d’une mémoire à une autobiographie, infléchir le grumeau de réel en l’empêchant de s’imposer comme destin, introduire une migration ? Comment travailler la haine et le sentiment de possession qui caractérisent ces patients ? L’auteur propose que c’est aussi grâce à la haine envers le nouvel objet qu’un mouvement rend possible des modulations différentes, des transformations par rapport à la configuration originelle, en réalisant un processus de désidentification. Les problèmes théoriques et techniques relatifs à cette complexe dynamique sont posés à partir de deux cas cliniques.
Pictorial essay: Interventional radiology in the management of hemodialysis vascular access - A single-center experience
Authors: Mammen Suraj , Keshava Shyamkumar N , Moses Vinu , Babu Surendra , Varughese Santhosh 
Published: April 2012

AbstractChronic kidney disease (CKD) is a worldwide public health problem and is associated with high morbidity and mortality. The majority of patients with CKD stage 5 (CKD-5), who cannot undergo renal transplant, depend on maintenance hemodialysis by surgically created access sites. Native fistulae are preferred over grafts due to their longevity. More than half of these vital portals for dialysis access will fail over time. Screening procedures to select high-risk patients before thrombosis or stenosis appears have resulted in aggressive management. These patients are referred for angiographic evaluation and/or therapy. We present the patterns of dialysis-related interventions done in our institution.
Percutaneous transhepatic embolization of biliary leakage with N-butyl cyanoacrylate
Authors: Carrafiello Gianpaolo , Ierardi Anna Maria , Piacentino Filippo , Cardim Larissa N 
Published: April 2012

AbstractBiliary leakage is a known complication after biliary surgery. In this report, we describe an uncommon treatment of a common biliary complication, wherein we used percutaneous transhepatic injection of N-butyl cyanoacrylate (NBCA) to treat a biliary leak in an 83-year-old patient.
Case report: Percutaneous treatment of multiple honeycomb-like liver hydatid cysts (type III CE2, according to WHO classification)
Authors: Corona Mario , Cannavale Alessandro , Bruni Antonio , Boatta Emanuele , Allegritti Massimiliano , Lucatelli Pierleone , Fanelli Fabrizio , Pucci Armando , Paciotti Carolina , Salvatori Filippo Maria 
Published: April 2012

AbstractPercutaneous treatment has been developing as a reliable and effective alternative to surgery in the treatment of liver hydatid cysts. However, percutaneous treatment is strongly recommended only for some types of hydatid cysts (types I and II). We report a patient with type III (CE2, according to the WHO classification) multiple liver hydatid cysts treated with the PAIR (puncture-aspiration-injection-reaspiration) technique. The patient developed a secondary biliary ﬁstula, which ultimately healed.
Bursae around the knee joints
Authors: Chatra Priyank S 
Published: April 2012

AbstractA bursa is a fluid-filled structure that is present between the skin and tendon or tendon and bone. The main function of a bursa is to reduce friction between adjacent moving structures. Bursae around the knee can be classified as those around the patella and those that occur elsewhere. In this pictorial essay we describe the most commonly encountered lesions and their MRI appearance.
Myositis ossificans imaging: keys to successful diagnosis
Authors: Lacout Alexis , Jarraya Mohamed , Marcy Pierre-Yves , Thariat Juliette , Carlier Robert Yves 
Published: April 2012

AbstractMyositis ossificans (MO) is an inflammatory pseudotumor of the muscle that may be mistaken clinically and even histologically for a malignant soft tissue tumor. The aim of this article is to report the imaging characteristics of MO, the emphasis being on the early diagnostic clues. USG can be used at an early stage to reveal the ′zone phenomenon,′ which is highly suggestive of MO. A short course of nonsteroidal anti-inflammatory drug therapy may be an efficient treatment for early MO.
CT scan diagnosis of hepatic adenoma in a case of von Gierke disease
Authors: Daga Bipin Valchandji , Shah Vaibhav R , More Rahul B 
Published: April 2012

AbstractHepatic adenoma is a well-defined, benign, solitary tumor of the liver. In individuals with glycogen storage disease I, adenoma tends to occur at a relatively younger age and can be multiple (adenomatosis). Imaging plays a pivotal role in diagnosing hepatic adenoma and in differentiating adenoma from other focal hepatic lesions. Especially in patients with von Gierke disease, in addition to the associated hepatomegaly caused by steatohepatitis and the diffusely reduced attenuation of the liver parenchyma seen on CT, there may be more than one hepatic adenoma in up to 40% of patients. Malignant degeneration of hepatic adenoma into hepatocellular carcinoma can occur and hence imaging is important for prompt diagnosis of adenoma and its complications. In this case report, we present a case of liver adenoma diagnosed by CT scan in a patient with von Gierke disease.
Multifocal intracranial astrocytoma in a pediatric patient with Ollier disease
Authors: Bathla Girish , Gupta Sarika , Ong Cheng 
Published: April 2012

AbstractOllier disease (OD) is a subtype of enchondromatosis. Historically, it has been distinguished from Maffucci syndrome (MS) by the presence of vascular malformations and nonskeletal neoplasms (NSN) in the latter. However, there is an increasing number of reports of NSN in OD, and this categorization is now being questioned. We report a case of OD complicated by multifocal astrocytoma in a young patient, once again pointing to a possible association between OD and NSN. We also review the available literature and examine the similarities between the reported cases.
Apoptosis of ectopic endometrial cells is impaired in women with endometriosis
Authors: De Paula Liv Braga , Braga Núbia Pereira , Mendonça Marcos , Moro Luciana , Geber Selmo 
Published: April 2012

Purpose This study was performed to assess the apoptotic index and Bcl-2 expression in ectopic endometrium of patients with endometriosis and in eutopic endometrium of patients without endometriosis, according to the phase of the menstrual cycle. Methods A total of eight patients with endometriosis and in eutopic endometrium of eight patients without endometriosis, according to the phase of the menstrual cycle. Samples were collected during surgical procedures and histologic sections were stained with hematoxylin-eosin and underwent morphometric analysis for assessment of the apoptotic index. TUNEL immunohistochemical assay was performed to validate the morphologic criteria used for quantification of apoptosis. Results The apoptotic index was significantly lower in the ectopic endometrium of patients with endometriosis in comparison to the eutopic endometrium of patients without endometriosis, regardless of the menstrual cycle phase. No statistically significant difference in endometrial Bcl-2 expression was observed among patients with and without endometriosis. Conclusions We conclude that ectopic endometrial tissues from women with endometriosis are less susceptible to apoptosis and these cells demonstrate an increased ability to survive and higher chances to colonize and grow in ectopic sites - important factors in the pathogenesis of endometriosis.
Comparison between GnRH agonist and antagonist protocols for severe endometriosis in assisted reproductive cycles
Authors: Ruggiero Maria , Viana Gersia Araujo , Di Berardino Olga Maria , Simi Giovanna , Papini Francesca , Genazzani Andrea Riccardo , Cela Vito , Artini Paolo Giovanni 
Published: April 2012

Purpose Endometriosis may influence different aspects of reproductive physiology including folliculogenesis, ovulation, embryo quality, and fertilization. Recent data demonstrate that patients with endometriosis-associated infertility undergoing in vitro fertilization (IVF) have a reduction of pregnancy rates compared to women with other indications for IVF. The aim of the study is to evaluate the outcomes of IVF after controlled ovarian hyperstimulation (COH) with GnRH antagonist (GnRH-ant) or GnRH agonist (GnRH-a) in severe endometriosis patients. Methods A total of 101 patients with severe endometriosis undergoing IVF cycles were retrospectively enrolled into two groups in relation to hypothalamic inhibition before COH, obtained respectively with leuprorelin and cetrorelix. We evaluated characteristics of COH and clinical outcomes (overall pregnancy rate, implantation rate, spontaneous miscarriages, ectopic pregnancies, and clinical pregnancy rates). Results The group treated with GnRH-ant presented a similar number of MII oocytes and good quality embryos while using a lower amount of gonadotropins. Outcomes of COH with both GnRH-ant and GnRH-a were similar in patients with stage III-IV endometriosis. The number of retrieved oocytes, the number of obtained embryos, the implantation rates, and the clinical pregnancy rates were similar with GnRH-ant and GnRH-a protocols. Conclusions Considering the pregnancy outcomes, COH with both GnRH-ant and GnRH-a protocols do not present statistical differences in patients with severe endometriosis, but the GnRH-ant protocol could be more convenient in term of gonadotropins amount and patient discomfort.
Nanoparticle‐Based Catalysis using Supramolecular Hydrogels
Authors: Léger Bastien , Menuel Stéphane , Ponchel Anne , Hapiot Frédéric , Monflier Eric 
Published: April 2012

AbstractA thermoregulated catalytic process has been elaborated using a ruthenium‐nanoparticle catalyst embedded into a supramolecular cyclodextrin‐based hydrogel matrix. Upon heating, the gel phase turned into a sol phase in which alkenes could be efficiently hydrogenated. Upon cooling, the reaction products and the metallic catalyst could be easily separated. The reusability of the system was clearly demonstrated.
Catalytic cracking of alkanes on FAU: Single‐event microkinetic modeling including acidity descriptors
Authors: Van Borm Rhona , Reyniers Marie‐Françoise , Marin Guy B. 
Published: April 2012

AbstractSingle‐event microkinetic (SEMK) modeling is applied to catalytic cracking of 2,2,4‐trimethylpentane on a series of faujasites with Si/Al ratio ranging from 2.6 to 30. Standard activation entropies of the various elementary reaction families are calculateda priorifrom transition state theory and statistical thermodynamics, while activation energies are estimated on a reference faujasite by regression to experimental kinetic data. The SEMK model is then extended with two acidity descriptors. The concentration of active sites is available from independent NH3‐TPD measurements, while the change in standard protonation enthalpy, relative to the reference faujasite, is obtained by regression to experimental kinetic data. The latter parameter accounts for the effect of the zeolite average acid strength both on the stability of the intermediates and on the activation energies of the protonation and protolytic scission reactions. For these five commercially available faujasites, a variation in standard protonation enthalpy of 29 kJ mol−1was found. © 2012 American Institute of Chemical Engineers AIChE J, 2012
Lenalidomide in multiple myeloma: Current status and future potential
Authors: Quach Hang , Kalff Anna , Spencer Andrew 
Published: April 2012

AbstractThe clinical development of lenalidomide (Revlimid™), then pomalidomide (Actimid™) as members of immunomodulatory drugs (IMiDs) for the treatment of multiple myeloma (MM), exemplifies how insight into disease biology can lead to design of effective therapeutic agents. Increased experience and understanding of IMiD's diverse biological effects has lead to rational design of lenalidomide‐based treatment‐regimens over recent years. However, much about lenalidomide is yet to be understood and fully exploited. Here, we review what is known of lenalidomide's biological effects, clinical certainties and uncertainties in the treatment of MM, and explore its future potential with other synergistic therapeutic agents. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
Role of serum free light chains in predicting HIV‐associated non‐Hodgkin lymphoma and Hodgkin's lymphoma and its correlation with antiretroviral therapy
Authors: Bibas Michele , Trotta Maria Paola , Cozzi‐Lepri Alessandro , Lorenzini Patrizia , Pinnetti Carmela , Rizzardini Giuliano , Angarano Gioacchino , Caramello Pietro , Sighinolfi Laura , Mastroianni Claudio Maria , Mazzarello Giovanni , Di Caro Antonino , Di Giacomo Cristina , d'Arminio Monforte Antonella , Antinori Andrea ,   for the ICONA Foundation Study Group
Published: April 2012

AbstractA nested case‐control study was performed within the Italian cohort of naïve to antiretroviral human immunodeficiency virus (HIV) patients (ICONA) cohort to evaluate the role of serum free light chains (sFLC) in predicting non‐Hodgkin's lymphoma (NHL) and Hodgkin lymphoma (HL) in HIV‐infected individuals. Of 6513 participants, 86 patients developed lymphoma and 46 of these (NHL, 30; HL, 16) were included in this analysis having stored prediagnostic blood. A total of 46 serum case samples matched 1:1 to lymphoma‐free serum control samples were assayed for κ and λ sFLC levels and compared by using conditional logistic regression. Because the polyclonal nature of free light chains (FLCs) was the focus of our study, we introduced the k + λ sum as the measurement of choice and as the primary variable studied. κ + λ sFLC values were significantly higher in patient with lymphoma than in controls, especially when considering samples stored 0–2‐year period before the lymphoma diagnosis. In the multivariable analysis, the elevation of sFLC predicted the risk of lymphoma independently of CD4 count, (odd ratio of 16.85 for k + λ sFLC >2‐fold upper normal limit (UNL) vs. normal value). A significant reduction in the risk of lymphoma (odd ratio of 0.07 in model with k + λ sFLC) was found in people with low sFLC and undetectable HIV viremia lasting more than 6 months. Our analysis indicates that an elevated polyclonal sFLC is a strong and sensitive predictor of the risk of developing lymphomas, and it is an easy to measure biomarker that merits consideration for introduction in routine clinical practice in people with HIV. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
JAK2 and genomic instability in the myeloproliferative neoplasms: A case of the chicken or the egg?
Authors: Scott Linda M. , Rebel Vivienne I. 
Published: April 2012

AbstractThe myeloproliferative neoplasms (MPNs) are a particularly useful model for studying mutation accumulation in neoplastic cells, and the mechanisms underlying their acquisition. This review summarizes our current understanding of the molecular defects present in patients with an MPN, and the effects of mutations targeting Janus kinase 2 (JAK2)‐mediated intracellular signaling on DNA damage and on the elimination of mutation‐bearing cells by programmed cell death. Moreover, we discuss findings that suggest that the acquisition of disease‐initiating mutations in hematopoietic stem cells of some MPN patients may be the consequence of an inherent genomic instability that was not previously appreciated. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.