bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure and Magnetic Ordering of the Anomalous Layered (2D) Ferrimagnet [NEt4]2MnII3(CN)8 and 3D Bridged‐Layered Antiferromagnet [NEt4]MnII3(CN)7 Prussian Blue Analogues
Authors: Kareis Christopher M. , Her Jae‐Hyuk , Stephens Peter W. , Moore Joshua G. , Miller Joel S. 
Published: June 2012

AbstractThe reaction of MnII and [NEt4]CN leads to the isolation of solvated [NEt4]Mn3(CN)7 (1) and [NEt4]2Mn3(CN)8 (2), which have hexagonal unit cells [1: R$\bar 3$m, a=8.0738(1), c=29.086(1) Å; 2: P$\bar 3$m1, a=7.9992(3), c=14.014(1) Å] rather than the face centered cubic lattice that is typical of Prussian blue structured materials. The formula units of both 1 and 2 are composed of one low‐ and two high‐spin MnII ions. Each low‐spin, octahedral [MnII(CN)6]4− bonds to six high‐spin tetrahedral MnII ions through the N atoms, and each of the tetrahedral MnII ions are bound to three low‐spin octahedral [MnII(CN)6]4− moieties. For 2, the fourth cyanide on the tetrahedral MnII site is C bound and is terminal. In contrast, it is orientationally disordered and bridges two tetrahedral MnII centers for 1 forming an extended 3D network structure. The layers of octahedra are separated by 14.01 Å (c axis) for 2, and 9.70 Å (c/3) for 1. The [NEt4]+ cations and solvent are disordered and reside between the layers. Both 1 and 2 possess antiferromagnetic superexchange coupling between each low‐spin (S=1/2) octahedral MnII site and two high‐spin (S=5/2) tetrahedral MnII sites within a layer. Analogue 2 orders as a ferrimagnet at 27(±1) K with a coercive field and remanent magnetization of 1140 Oe and 22 800 emuOe mol−1, respectively, and the magnetization approaches saturation of 49 800 emuOe mol−1 at 90 000 Oe. In contrast, the bonding via bridging cyanides between the ferrimagnetic layers leads to antiferromagnetic coupling, and 3D structured 1 has a different magnetic behavior to 2. Thus, 1 is a Prussian blue analogue with an antiferromagnetic ground state [Tc=27 K from d(χT)/dT].
Cleanability of Food Contact Surfaces with Water Jets
Authors: Mauermann Marc , Majschak Jens‐Peter , Bley Thomas , Bellmann Cornelia , Calvimontes Alfredo , Caspari Anja 
Published: June 2012

AbstractDer Einfluss der Eigenschaften von produktberührenden Oberflächen auf die Reinigbarkeit ist nicht nur in der Lebensmittelindustrie ein intensiv diskutiertes Thema. In diesem Beitrag werden Untersuchungsergebnisse zur Abhängigkeit der Reinigungsrate von der Oberflächenrauigkeit, Oberflächenenergie und den elektrostatischen Eigenschaften der zu reinigenden Oberfläche vorgestellt. Als Testverschmutzungen wurden auf die modifizierten Edelstahlproben verkleisterte Kartoffelstärke und denaturiertes Molkenprotein aufgetragen. Die Reinigung erfolgte mittels Flüssigkeitsstrahl aus einer Flachstrahldüse.
A sensitive period for shibboleths: The long tail and changing goals of speech perception over the course of development
Authors: Zevin Jason D. 
Published: June 2012

AbstractIt is clear that the ability to learn new speech contrasts changes over development, such that learning to categorize speech sounds as native speakers of a language do is more difficult in adulthood than it is earlier in development. There is also a wealth of data concerning changes in the perception of speech sounds during infancy, such that infants quite rapidly progress from language‐general to more language‐specific perceptual biases. It is often suggested that the perceptual narrowing observed during infancy plays a causal role in the loss of plasticity observed in adulthood, but the relationship between these two phenomena is complicated. Here I consider the relationship between changes in sensitivity to speech sound categorization over the first 2 years of life, when they appear to reorganize quite rapidly, to the “long tail” of development throughout childhood, in the context of understanding the sensitive period for speech perception. © 2012 Wiley Periodicals,Inc. Dev Psychobiol 54: 632–642, 2012.
Generation of uniform discharge by dielectric barrier discharge device in atmospheric‐pressure air
Authors: Osawa Naoki , Yoshioka Yoshio , Hanaoka Ryoichi , Mochizuki Yutarou , Kobayashi Yusuke , Yamada Yuta 
Published: June 2012

AbstractWe found that the generation of a uniform discharge in atmospheric‐pressure air was possible in the frequency range from 32 Hz to 1.1 kHz using alumina as a barrier material of the DBD (Dielectric Barrier Discharge) device. We also found that there is a voltage domain for the generation of the uniform discharge. The domain becomes wider with the increase of the frequency. If the applied voltage is slightly higher than the upper limit voltage of stable generation of a uniform discharge, the uniform discharge changes to a nonuniform FD (Filamentary Discharge). In order to clarify the mechanism of generation of the uniform discharge, we investigated how the barrier materials change the discharge mode by both photographic observation and analysis of electric circuit phenomena. We also carried out experiments with a DBD device, using a combination barrier of soda glass and alumina. In this case, the uniform discharge and the FD appeared alternately in every half cycle. As a result, it was found that a uniform discharge was generated when the alumina barrier was used and it acted as a cathode. From analysis of the gap voltage and the current, it was also found that the uniform discharge was an APTD (Atmospheric Pressure Townsend Discharge) characterized by electron avalanche. This paper presents the experimental results and discussions. © 2012 Wiley Periodicals, Inc. Electr Eng Jpn, 180(4): 1–9, 2012; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/eej.21253
Cavity Effect on Perrhenate Recognition by Polyammonium Cages
Authors: Amendola Valeria , Alberti Giancarla , Bergamaschi Greta , Biesuz Raffaela , Boiocchi Massimo , Ferrito Stefania , Schmidtchen Franz‐Peter 
Published: June 2012

AbstractThe affinity of azacryptands towards perrhenate has been investigated by potentiometric, 1H NMR spectroscopic and ITC studies in aqueous solutions. The association constants could only be determined for the p‐xylyl and m‐xylyl azacryptands in the hexaprotonated form. The experimental results showed the outstanding affinity of the p‐xylyl cryptand for perrhenate, attributable to the geometric complementarity between the anion and the cavity of the receptor. Single crystals of the inclusion complex could also be obtained. The X‐ray diffraction studies indicate that the perrhenate anion is included in the cavity of the receptor and interacts with the ammonium groups by means of both direct and water‐mediated H‐bonding interactions. The receptors were also investigated in the presence of different anions (i.e. chloride, bromide, iodide, perchlorate and nitrate). The affinity trend demonstrates that the p‐xylyl cryptand cavity is more suitable to host large anionic guests such as perrhenate, perchlorate and iodide, despite their low density charge. On the contrary, nitrate, bromide and chloride fit better into the smaller cavity of the m‐xylyl cryptand. The higher affinity of the m‐xylyl cage towards chloride over that of perrhenate was also demonstrated by the crystal structure of the 1:1 adduct.
Self‐induced accumulation of glutamate in striatal astrocytes and basal ganglia excitotoxicity
Authors: Morales Ingrid , Rodriguez Manuel 
Published: June 2012

AbstractExcitotoxicity induced by high levels of extracellular glutamate (GLU) has been proposed as a cause of cell degeneration in basal ganglia disorders. This phenomenon is normally prevented by the astrocytic GLU‐uptake and the GLU‐catabolization to less dangerous molecules. However, high‐GLU can induce reactive gliosis which could change the neuroprotective role of astrocytes. The striatal astrocyte response to high GLU was studied here in an in vivo rat preparation. The transient striatal perfusion of GLU (1 h) by reverse microdialysis induced complex reactive gliosis which persisted for weeks and which was different for radial‐like glia, protoplasmic astrocytes and fibrous astrocytes. This gliosis was accompanied by a persistent cytosolic accumulation of GLU (immunofluorescence quantified by confocal microscope), which persisted for weeks (self‐induced glutamate accumulation), and which was associated to a selective decrease of glutamine synthetase activity. This massive and persistent self‐induced glutamate accumulation in striatal astrocytes could be an additional factor for the GLU‐induced excitotoxicity, which has been implicated in the progression of different basal ganglia disorders. © 2012 Wiley Periodicals, Inc.
Preparation of Cu(OAc)2/MCM‐41 catalyst and its application in the one‐pot synthesis of 1,2,3‐triazoles in water
Authors: Hosseinzadeh Rahman , Sepehrian Hamid , Shahrokhi Farshid 
Published: June 2012

AbstractAn efficient one‐pot synthesis of 1,2,3‐triazoles via the three‐component coupling reaction between benzyl or alkyl bromides, terminal alkynes, and sodium azide in the presence of catalytic amounts of Cu(OAc)2/MCM‐41 catalyst has been described. This catalyst showed high catalytic activity and 1,4‐regioselectivity for the [3 + 2]Huisgen cycloaddition. This method avoids isolation and handling of organic azides, using water as a solvent, and catalyst recycling makes this synthesis a truly green procedure. © 2012 Wiley Periodicals, Inc. Heteroatom Chem 23:415–421, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21031
Reconstructive outcomes in patients with head and neck sarcoma
Authors: Chao Albert H. , Sturgis Erich M. , Yu Peirong , Skoracki Roman J. , Guadagnolo B. Ashleigh , Hanasono Matthew M. 
Published: June 2012

AbstractBackgroundLimited data exist regarding reconstructive outcomes in patients with head and neck sarcoma.MethodsA review of patients with head and neck sarcoma who underwent oncologic resection and microvascular free flap reconstruction between 2001 and 2010 was performed.ResultsIn all, 133 patients were included in the study. The overall rate of perioperative complications was 30.1%, including a flap loss rate of 3.0%. The rate of late recipient site complications was 7.5% and occurred more frequently with postoperative radiation (19.0%) compared with preoperative radiation, prior radiation, and no radiation (5.3%, 3.0%, and 0%, respectively; p = .005). Most patients achieved intelligible speech (88.3%) and feeding tube independence (94.4%).ConclusionsGood reconstructive outcomes can be attained in patients with head and neck sarcoma undergoing resection and free flap reconstruction. Preoperative radiation may be preferable to postoperative radiation in select cases due to fewer long‐term complications without an increased rate of complications or flap loss. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
Ipsilateral and contralateral central lymph node metastasis in papillary thyroid cancer: Patterns and predictive factors of nodal metastasis
Authors: Lee Kyu Eun , Chung Il Yong , Kang Eunyoung , Koo Do Hoon , Kim Kyu Hyung , Kim Sung‐Won , Youn Yeo‐Kyu , Oh Seung Keun 
Published: June 2012

AbstractBackgroundThe aims of this study were to evaluate the rate and risk factors of ipsilateral and contralateral central lymph node (CLN) metastases in patients with papillary thyroid cancer (PTC).MethodsA total of 161 patients who underwent total thyroidectomy with prophylactic CLN dissection (CLND) to treat PTC were enrolled.ResultsOf 134 total cases excluding tumors located in the isthmus and bilateral lobes, 72 cases (53.7%) involved CLN metastases. Tumor size, age, and sex were found to be predictive of ipsilateral CLN metastasis and the rate of ipsilateral CLN metastasis in tumors > 1 cm was 59.6%. Contralateral CLN metastases were more prevalent only in tumors that already had ipsilateral CLN metastases (27.3%, p = .002).ConclusionsIt is suggested that risk factors of ipsilateral and contralateral CLN metastases should be considered while planning the extent of CLND in patients with clinically node‐negative and unilateral PTC upon preoperative ultrasonography. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
Endoscopic transpterygoid nasopharyngectomy: Correlation of surgical anatomy with multiplanar CT
Authors: Hosseini Seid Mousa Sadr , McLaughlin Nancy , Carrau Ricardo L. , Otto Bradley , Prevedello Daniel M. , Solares C. Arturo , Zanation Adam M. , Kassam Amin B. 
Published: June 2012

AbstractBackgroundOncologic resection of the nasopharynx is challenging due to its complex and deep‐seated nature. We aimed to illustrate the anatomic landmarks of endoscopic nasopharyngectomy and design a surgical training model that could facilitate learning of this technique.MethodsAn endoscopic endonasal dissection of the nasopharynx was completed in fresh cadaveric specimens under conditions similar to those of our operating suite. Digital data from a high‐resolution CT scan were imported to an image guidance system to be used during the dissections.ResultsWe expanded the sinonasal corridor, harvested a contralateral nasoseptal flap, and exposed the pterygopalatine and infratemporal fossae. A detailed anatomic dissection of the nasopharynx was correlated to multiplanar images provided by the image guidance system, highlighting appropriate bony, neural, and vascular landmarks.ConclusionsUnderstanding the anatomy‐based endoscopic modular approaches facilitates planning and safe execution of an oncologic nasopharyngectomy. Clinical experience remains mandatory because anatomic models fall short of clinical scenarios. © 2012 Wiley Periodicals, Inc. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
Influence of pretreatment social support on health‐related quality of life in head and neck cancer survivors: Results from a prospective study
Authors: Howren M. Bryant , Christensen Alan J. , Hynds Karnell Lucy , Van Liew Julia R. , Funk Gerry F. 
Published: June 2012

AbstractBackgroundHead and neck cancer and its treatment can have considerable impact on health‐related quality of life (HRQOL). The present study investigated whether social support, assessed before treatment, predicted HRQOL outcomes up to 12 months later in head and neck cancer survivors.MethodsUsing a prospective longitudinal design, patients (n = 364) were assessed on several clinical and psychosocial characteristics at diagnosis and then at 3‐ and 12‐month follow‐up appointments. HRQOL was assessed with the Short Form Health Survey (SF‐36) and the Head and Neck Cancer Inventory (HNCI).ResultsHierarchical multiple regression analyses demonstrated that greater perceived support present at diagnosis significantly predicted more favorable global and head and neck cancer‐specific HRQOL at 3‐ and 12‐month follow‐up.ConclusionResults suggest that adequate social support at diagnosis can have a significant, positive impact on HRQOL in head and neck cancer survivors. Thus, it may be useful to evaluate support resources at diagnosis in order to identify individuals at risk for poor HRQOL outcomes. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk
Authors: Lacko Martin , Voogd Adri C. , Roelofs Hennie M. J. , te Morsche Rene H. M. , Ophuis Michel B. Oude , Peters Wilbert H. M. , Manni Johannes J. 
Published: June 2012

AbstractBackgroundCombinations of genetic polymorphisms in biotransformation enzymes might modify the individual risk for head and neck cancer.MethodsBlood from 432 patients with head and neck cancer and 437 controls was investigated for genetic polymorphisms in 9 different phase I and II biotransformation enzymes. Analysis of the risk‐modifying effect was performed according to predicted enzyme activities, based on genetic polymorphisms in the corresponding genes.ResultsCombination of polymorphisms in COX‐2 or EPHX1 with high activity polymorphisms in UGT1A1, UGT1A6, or UGT1A7 showed a risk‐modulating effect in head and neck carcinogenesis, especially among heavy smokers and patients with laryngeal cancer. However, no additional effect for the combination of these polymorphisms was discovered when compared to the impact of polymorphism in UGT1A1, UGT1A6, and UGT1A7 individually.ConclusionPredicted high activity polymorphisms in the phase II enzymes UGT1A1, UGT1A6, and UGT1A7 are associated with an increased risk of head and neck cancer. Head Neck, 2012
Association of VO2 and VCO2 rate variability with serum glucose, insulin, and glucose intolerance
Authors: Satué‐Rodríguez Julián , Méndez José D. 
Published: June 2012

AbstractChanges in the cellular metabolism assessed by the variability of oxygen consumption (VO2) and carbon dioxide production (VCO2) as well as the association of serum glucose and insulin to energy spectral density (ESD) of VO2 and VCO2 were evaluated. Ten nonglucose intolerant and 10 glucose intolerant subjects, aged 21–70 years, were included. Glucose and insulin concentrations and VO2 and VCO2 records were collected every 10 min during 3 h. ESD of VO2 and VCO2 was estimated and associated with glucose and insulin concentrations. Statistical significance in glucose levels, insulin, and ESD of VO2 and VCO2 among nonglucose intolerant subjects and glucose and insulin among glucose intolerance subjects at postload glucose (PLG) state compared with basal state was found. Moreover, glucose was significantly higher in glucose intolerance subjects than nonglucose intolerant subjects for basal and PLG states. These results show an increment in ESD of VO2 and VCO2 at PLG state among nonglucose intolerant subjects and suggest that their measurement may be a key indicator of the variability of cellular metabolic activity and contribute to confirm disturbances in glucose metabolism. © 2012 IUBMB IUBMB Life, 64(8): 705–709, 2012
Binding of phosphatidic acid to 14‐3‐3 proteins hampers their ability to activate the plant plasma membrane H+‐ATPase
Authors: Camoni Lorenzo , Di Lucente Cristina , Pallucca Roberta , Visconti Sabina , Aducci Patrizia 
Published: June 2012

AbstractPhosphatidic acid is a phospholipid second messenger implicated in various cellular processes in eukaryotes. In plants, production of phosphatidic acid is triggered in response to a number of biotic and abiotic stresses. Here, we show that phosphatidic acid binds to 14‐3‐3 proteins, a family of regulatory proteins which bind client proteins in a phosphorylation‐dependent manner. Binding of phosphatidic acid involves the same 14‐3‐3 region engaged in protein target binding. Consequently, micromolar phosphatidic acid concentrations significantly hamper the interaction of 14‐3‐3 proteins with the plasma membrane H+‐ATPase, a well characterized plant 14‐3‐3 target, thus inhibiting the phosphohydrolitic enzyme activity. Moreover, the proton pump is inhibited when endogenous PA production is triggered by phospholipase D and the G protein agonist mastoparan‐7. Hence, our data propose a possible mechanism involving PA that regulates 14‐3‐3‐mediated cellular processes in response to stress. © 2012 IUBMB IUBMB Life, 64(8): 710–716, 2012
Pain tolerance in children and adolescents: Sex differences and psychosocial influences on pain threshold and endurance
Authors: Schmitz A‐K. , Vierhaus M. , Lohaus A. 
Published: June 2012

AbstractBackgroundLaboratory studies with children and adolescents revealed inconsistent findings regarding sex differences in pain tolerance, although lower pain tolerance is commonly reported for adult women. Besides biological mechanisms, several socio‐cognitive variables are discussed which may influence pain tolerance in regard to sex differences. The purpose of the present study was to investigate the pain tolerance of children and adolescents using the cold pressor task (CPT) and to analyse influences of pain‐coping and pain‐related self‐efficacy.MethodsAbout 1021 children and adolescents aged 9–17 participated in the study. Pain tolerance was defined as the length of time a participant's hand remains under water during the CPT. Two phases of pain tolerance were differentiated: the time until pain is reported (pain threshold) and the time from the threshold until the pain increases to a level resulting in the hand being withdrawn (pain endurance). Pain‐coping and pain‐related self‐efficacy were assessed by self‐report questionnaires.ResultsWe revealed an obvious effect of sex on pain threshold, which increased with age, a small effect on pain tolerance and no significant effect on endurance. Independent of sex, pain endurance was influenced by pain‐related self‐efficacy and positive self‐instruction.ConclusionsOur results support the assumption that female and male adolescents develop in different directions regarding their pain tolerance when reaching puberty. This seems mainly attributable to a decrease of pain threshold in girls. In contrast, boys and girls are able to endure pain to an equal extent influenced, however, by self‐efficacy and coping variables.
Selective glucocorticoid receptor modulation maintains bone mineral density in mice
Authors: Thiele Sylvia , Ziegler Nicole , Tsourdi Elena , De Bosscher Karolien , Tuckermann Jan P , Hofbauer Lorenz C , Rauner Martina 
Published: June 2012

Abstract
Glucocorticoids (GCs) are potent anti-inflammatory drugs, but their use is limited by their adverse effects on the skeleton. Compound A (CpdA) is a novel GC receptor modulator with the potential for an improved risk/benefit profile. We tested the effects of CpdA on bone in a mouse model of GC-induced bone loss. Bone loss was induced in FVB/N mice by implanting slow-release pellets containing either vehicle, prednisolone (PRED) (3.5 mg), or CpdA (3.5 mg). After 4 weeks, mice were killed to examine the effects on the skeleton using quantitative computed tomography, bone histomorphometry, serum markers of bone turnover, and gene expression analysis. To assess the underlying mechanisms, in vitro studies were performed with human bone marrow stromal cells (BMSCs) and murine osteocyte-like cells (MLO-Y4 cells). PRED reduced the total and trabecular bone density in the femur by 9% and 24% and in the spine by 11% and 20%, respectively, whereas CpdA did not influence these parameters. Histomorphometry confirmed these results and further showed that the mineral apposition rate was decreased by PRED whereas the number of osteoclasts was increased. Decreased bone formation was paralleled by a decline in serum procollagen type 1 N-terminal peptide (P1NP), reduced skeletal expression of osteoblast markers, and increased serum levels of the osteoblast inhibitor dickkopf-1 (DKK-1). In addition, serum CTX-1 and the skeletal receptor activator of NF-κB ligand (RANKL)/osteoprotegerin (OPG) ratio were increased by PRED. None of these effects were observed with CpdA. Consistent with the in vivo data, CpdA did not increase the RANKL/OPG ratio in MLO-Y4 cells or the expression of DKK-1 in bone tissue, BMSCs, and osteocytes. Finally, CpdA also failed to transactivate DKK-1 expression in bone tissue, BMSCs, and osteocytes. This study underlines the bone-sparing potential of CpdA and suggests that by preventing increases in the RANKL/OPG ratio or DKK-1 in osteoblast lineage cells, GC-induced bone loss may be ameliorated. © 2012 American Society for Bone and Mineral Research.