bluuebunny/crossref_metadata_2025_split huggingface dataset:
SOIL BIOLOGICAL AND BIOCHEMICAL QUALITY OF WHEAT-MAIZE CROPPING SYSTEM IN LONG-TERM FERTILIZER EXPERIMENTS
Authors: HU CHENG , QI YING-CHUN 
Published: June 2011

SUMMARYTwo long-term field experiments, each consisting of three treatments (organic compost treatment, chemical fertilizer treatment and an untreated control) were established in 1993 and 1997, respectively. Soil samples were collected from each plot in June 2004 and 2005 after crop harvest and were used to determine soil physical-chemical properties, biological and biochemical activity, and the nematode community. Soil physicochemical parameters, microbial biomass, biological activities and nematode communities were significantly influenced by long-term application of organic compost. In general, soil total organic carbon, dissolved organic carbon, total nitrogen, alkaline-hydrolysable nitrogen, available phosphorus, and available potassium, microbial biomass, basal respiration, urease activities, total number of nematodes and bacterial-feeding nematodes were significantly higher in the compost plots than in the chemical fertilizer and control plots at two experimental sites and two sampling dates. Soil bulk density and pH values were significantly lower in the compost plots. We conclude that soil physical-chemical properties, size and activity of soil microbial biomass, metabolic quotient (qCO2), urease activity, total number of nematodes and bacteria-feeding nematodes could be used as indicators of soil quality.
Recentred local profiles for authorship attribution
Authors: LAYTON ROBERT , WATTERS PAUL , DAZELEY RICHARD 
Published: June 2011

AbstractAuthorship attribution methods aim to determine the author of a document, by using information gathered from a set of documents with known authors. One method of performing this task is to create profiles containing distinctive features known to be used by each author. In this paper, a new method of creating an author or document profile is presented that detects features considered distinctive, compared to normal language usage. Thisrecentreingapproach creates more accurate profiles than previous methods, as demonstrated empirically using a known corpus of authorship problems. This method, named recentred local profiles, determines authorship accurately using a simple ‘best matching author’ approach to classification, compared to other methods in the literature. The proposed method is shown to be more stable than related methods as parameter values change. Using a weighted voting scheme, recentred local profiles is shown to outperform other methods in authorship attribution, with an overall accuracy of 69.9% on thead-hocauthorship attribution competition corpus, representing a significant improvement over related methods.
The association between excess weight and self-rated health and psychological distress in women in Spain
Authors: Martín-López Rocío , Pérez-Farinós Napoleon , Hernández-Barrera Valentín , de Andres Ana Lopez , Carrasco-Garrido Pilar , Jiménez-García Rodrigo 
Published: June 2011

AbstractObjectiveTo investigate the associations between obesity and self-rated health and psychological well-being in Spanish women.DesignCross-sectional study. Three dependent variables were defined: self-rated health; self-declared diagnosis of psychiatric disorders or use of psychiatric drugs; and General Health Questionnaire-12 (GHQ-12) score. A set of variables (sociodemographic, morbidity and lifestyle) were used to adjust for possible confounding effects.SettingThe National Health Survey was conducted in Spain in 2006.SubjectsA total of 15 099 women aged ≥18 years. Participants were classified into groups according to their BMI.ResultsIn all, 55·4 % of the women had normal weight, 29·4 % were overweight and 15·2 % were obese. Self-perception of poor health in obese women was 57·8 %, a significantly higher value than in women of normal weight (28·8 %). Prevalence of psychiatric disease was 35·5 % in obese women and 18·9 % in women of normal weight. In multivariate analysis, obese women had 34 % higher odds of declaring poor self-perception of health (OR = 1·34; 95 % CI 1·12, 1·61), 18 % higher odds of self-reporting psychiatric disease (OR = 1·18; 95 % CI 1·02, 1·38) and 26 % higher odds (OR = 1·26; 95 % CI 1·02, 1·55) of having an abnormal outcome (≥3) on the GHQ-12 than women of normal weight.ConclusionsThe present study highlights that obese Spanish women have worse self-rated health and psychological health than those with normal weight. These aspects are relevant because of the growing importance placed on the functionality of patients and their mental health within the obesity epidemic.
Folic acid awareness and intake among women in areas with high prevalence of neural tube defects in China: a cross-sectional study
Authors: Zeng Ziqian , Yuan Ping , Wang Yanping , Ma Xi , Zhu Jun 
Published: June 2011

AbstractObjectiveTo measure folic acid awareness and intake rates among women of childbearing age in certain areas of China with a high prevalence of neural tube defects (NTD).DesignA cross-sectional survey was carried out utilising a nineteen-item questionnaire enquiring into individual women's knowledge of, attitude towards and practice of folic acid supplementation.SettingA total of 293 low-income counties in six provinces of China.SubjectsWomen aged 19–44 years from six provinces with a high prevalence of NTD recruited from June to August 2008.ResultsAmong 33 025 participants, 57 % had heard of folic acid but only 15 % knew all of the core information. The intake rate was 12 %; only 8 % took the recommended dose and only 4 % of non-pregnant women took folic acid. Some women did not take folic acid because they did not know that they should take it (49 %) or they had misconceptions about it (24 %). According to logistic regression analysis, rural residence was a risk factor for folic acid awareness. Ethnicity, educational level, average annual income per person and pregnancy were the influencing factors of folic acid awareness and folic acid intake.ConclusionsAlthough more than half of the respondents had heard of folic acid, the intake rate was still very low in areas with a high prevalence of NTD. Thus, more efforts are needed to increase folic acid awareness and intake among women of reproductive age in these areas.
FACIL: Fast and Accurate Genetic Code Inference and Logo
Authors: Dutilh Bas E. , Jurgelenaite Rasa , Szklarczyk Radek , van Hijum Sacha A.F.T. , Harhangi Harry R. , Schmid Markus , de Wild Bart , Françoijs Kees−Jan , Stunnenberg Hendrik G. , Strous Marc , Jetten Mike S.M. , Op den Camp Huub J.M. , Huynen Martijn A. 
Published: June 2011

Abstract
Motivation: The intensification of DNA sequencing will increasingly unveil uncharacterized species with potential alternative genetic codes. A total of 0.65% of the DNA sequences currently in Genbank encode their proteins with a variant genetic code, and these exceptions occur in many unrelated taxa.
Results: We introduce FACIL (Fast and Accurate genetic Code Inference and Logo), a fast and reliable tool to evaluate nucleic acid sequences for their genetic code that detects alternative codes even in species distantly related to known organisms. To illustrate this, we apply FACIL to a set of mitochondrial genomic contigs of Globobulimina pseudospinescens. This foraminifer does not have any sequenced close relative in the databases, yet we infer its alternative genetic code with high confidence values. Results are intuitively visualized in a Genetic Code Logo.
Availability and implementation: FACIL is available as a web-based service at http://www.cmbi.ru.nl/FACIL/ and as a stand-alone program.
Contact: dutilh@cmbi.ru.nl.
Supplementary information: Supplementary data are available at Bioinformatics online.
Cdc45: the missing RecJ ortholog in eukaryotes?
Authors: Sanchez-Pulido Luis , Ponting Chris P. 
Published: June 2011

Abstract
Summary: DNA replication is one of the most ancient of cellular processes and functional similarities among its molecular machinery are apparent across all cellular life. Cdc45 is one of the essential components of the eukaryotic replication fork and is required for the initiation and elongation of DNA replication, but its molecular function is currently unknown. In order to trace its evolutionary history and to identify functional domains, we embarked on a computational sequence analysis of the Cdc45 protein family. Our findings reveal eukaryotic Cdc45 and prokaryotic RecJ to possess a common ancestry and Cdc45 to contain a catalytic site within a predicted exonuclease domain. The likely orthology between Cdc45 and RecJ reveals new lines of enquiry into DNA replication mechanisms in eukaryotes.
Contact: luis.sanchezpulido@dpag.ox.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
The Biological Connection Markup Language: a SBGN-compliant format for visualization, filtering and analysis of biological pathways
Authors: Beltrame Luca , Calura Enrica , Popovici Razvan R. , Rizzetto Lisa , Guedez Damariz Rivero , Donato Michele , Romualdi Chiara , Draghici Sorin , Cavalieri Duccio 
Published: June 2011

Abstract
Motivation: Many models and analysis of signaling pathways have been proposed. However, neither of them takes into account that a biological pathway is not a fixed system, but instead it depends on the organism, tissue and cell type as well as on physiological, pathological and experimental conditions.
Results: The Biological Connection Markup Language (BCML) is a format to describe, annotate and visualize pathways. BCML is able to store multiple information, permitting a selective view of the pathway as it exists and/or behave in specific organisms, tissues and cells. Furthermore, BCML can be automatically converted into data formats suitable for analysis and into a fully SBGN-compliant graphical representation, making it an important tool that can be used by both computational biologists and ‘wet lab’ scientists.
Availability and implementation: The XML schema and the BCML software suite are freely available under the LGPL for download at http://bcml.dc-atlas.net. They are implemented in Java and supported on MS Windows, Linux and OS X.
Contact: duccio.cavalieri@unifi.it; sorin@wayne.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Probability-based surveying using self-sampling to estimate catch and effort in Norway's coastal tourist fishery
Authors: Vølstad J. H. , Korsbrekke K. , Nedreaas K. H. , Nilsen M. , Nilsson G. N. , Pennington M. , Subbey S. , Wienerroither R. 
Published: June 2011

Abstract
Vølstad, J. H., Korsbrekke, K., Nedreaas, K. H., Nilsen, M., Nilsson, G. N., Pennington, M., Subbey, S., and Wienerroither, R. 2011. Probability-based surveying using self-sampling to estimate catch and effort in Norway's coastal tourist fishery. – ICES Journal of Marine Science, 68: 1785–1791. Recreational fishing as a tourist activity has become an increasingly important part of the Norwegian travel industry and may contribute significantly to the fishing mortality on Norwegian coastal cod (Gadus morhua). Quantifying catches in the tourist fishery is made difficult by Norway's intricate and long coastline, and the lack of a fishing licence system, a registry of businesses catering for fishing tourists, and a registry of charter boats. A probability-based survey was used to estimate annual catch and effort by boat for anglers associated with 445 tourist-fishing businesses during 2009. From a stratified random sample of businesses, fishing tourists were recruited systematically over time to record their daily catch and effort in diaries. Cod dominated the reported landed catch (harvest) north of 62°N, and saithe and mackerel dominated south of 62°N. The estimated total landed catch of all species taken by tourist fishers in the business sector during 2009 was 3335 t (relative standard error, RSE = 17%), of which 1613 t (RSE = 22%) were cod. It is concluded that surveys based on self-sampling can yield accurate estimates of catch and effort accounted for by the business sector of the Norwegian tourist fishery and that the tourist catch of coastal cod is insignificant compared with the commercial and recreational catch by local residents.
Reducing uncertainty in the assessment and management of fish resources following an environmental impact
Authors: Rotherham Douglas , Macbeth William G. , Kennelly Steven J. , Gray Charles A. 
Published: June 2011

Abstract
Rotherham, D., Macbeth, W. G., Kennelly, S. J., and Gray, C. A. 2011. Reducing uncertainty in the assessment and management of fish resources following an environmental impact. – ICES Journal of Marine Science, 68: 1726–1733. The limitations of using information from commercial fisheries for assessing and managing resources and ecosystems are well known. Although fishery-independent data may overcome many such limitations, few studies have examined how incorporating data from different sources affects assessments and subsequent management decisions. Here, the value of integrating data from two types of sampling survey to assess the recovery of faunal populations following a severe fish-kill event in the Richmond River (New South Wales, Australia) in 2008 is evaluated. There is occasional large-scale mortality of fish and invertebrates in certain estuaries of eastern Australia following major flood events. In extreme cases, the management response involves closing an entire estuary to all fishing, to facilitate the recolonization and recovery of fish and other fauna. Decisions to resume normal fishing activities have environmental, economic, and social implications. Using lessons learned from a similar fish-kill event in 2001, it is shown how, in 2008, fishery-independent sampling, combined with improved sampling by commercial fishers, reduced uncertainty in decision-making and led to greatly improved socio-economic outcomes for stakeholders. The work highlights the need to examine the value of different sources of information to improve management decisions.
The Safety Profile of Home Infusion of Intravenous Immunoglobulin in Patients With Neuroimmunologic Disorders
Authors: Souayah Nizar , Hasan Ashar , Khan Hafiz M R , Yacoub Hussam A , Jafri Mohsin 
Published: June 2011

Objectives:
To assess the overall safety of high-dose intravenous immunoglobulin (IG) products used to treat patients with neuroimmunological disorders in a supervised home-based setting.

Methods:
The incidence of adverse reactions was assessed in a retrospective chart review of 420 patients who consecutively received 4076, home-based, individual, intravenous immunoglobulin (IVIG) infusions between January 2009 and December 2009.

Results:
A total of 90 patients (21.4%) developed adverse reactions related to IVIG administration (2.6% per individual infusion). A total of 95.5% of adverse reactions were mild, and no serious side effects were observed. The incidence of adverse reactions was significantly lower in the subgroup of patients with neuroimmunological disorders who received premedication (18.2% compared with 29.3%, P = 0.02). There was no significant statistical difference in the incidence of side effects among the different brands of IVIG used in this study.

Conclusions:
The combination of premedication and well-defined clinical, IVIG infusion policies may reduce the incidence of high-dose IVIG adverse reactions administered in a home-based setting in patients with neuroimmunological disorders.
High resolution manometry to detect transient lower oesophageal sphincter relaxations: diagnostic accuracy compared with perfused‐sleeve manometry, and the definition of new detection criteria
Authors: Roman S. , Zerbib F. , Belhocine K. , Bruley des Varannes S. , Mion F. 
Published: June 2011

Aliment Pharmacol Ther 2011; 34: 384–393SummaryBackground  Inhibition of transient lower oesophageal sphincter relaxations (tLESRs) has become one of the most relevant therapeutic objectives in patients with reflux symptoms resistant to proton pump inhibitors. tLESRs are currently detected by oesophageal perfused‐sleeve manometry (PSM), but oesophageal high resolution manometry (HRM), which combines closely spaced pressure sensors and oesophageal pressure topography plots, may prove to be a better tool.Aim  To evaluate the efficacy, reproducibility and interobserver agreement of HRM for the detection of tLESRs, in comparison with PSM.Methods  Twenty‐four healthy volunteers underwent HRM alone and on a separate occasion with PSM simultaneously. LES pressure was monitored for 1 h during fasting and 2 h postprandial. Criteria for tLESRs were defined by characterising spontaneous LES relaxation associated with common cavity and then applied to all spontaneous LES relaxations. Interobserver agreement and the rates of tLESRs detected by HRM and PSM were compared.Results  New HRM criteria for the detection of tLESRs have been established. A similar number of tLESRs were identified during the two HRM recordings (median per subject 15 and 13 (P = 0.07) and less with PSM (median per subject 11, P < 0.01). The overall concordance rate between the two procedures was substantial (kappa = 0.61). The interobserver agreement was almost perfect (kappa = 0.83) with HRM and only fair (kappa = 0.38) with PSM.Conclusions  High resolution manometry is reproducible and more sensitive than PSM to detect tLESRs. HRM provides a better interobserver agreement. These results confirm that HRM is the gold standard for detecting tLESRs (NTC00931593).
Plasma concentrations of etomidate during an intravenous infusion over 48 hours
Authors: HEBRON B. S. 
Published: June 2011

SummaryTwo groups of six patients who had undergone major maxillofacial surgery and who required intermittent positive pressure ventilation, analgesia and sedation for about 48 hours postoperatively were studied. Analgesia in the postoperative period was maintained by an infusion of fentanyl 0.034 μg/kg/minute. Sedation was maintained with an intravenous infusion of etomidate such that the patients slept but opened their eyes when addressed and obeyed commands. An assay method was developed which enabled the measurement of plasma concentration of etomidate for periods of up to 24 hours after stopping the infusion. The steady slate plasma concentration associated with the technique which produced the required degree of sedation was found to be 158 μg/litre (SEM 36). Etomidate exhibited linear pharmacokinetics and the decrease in plasma concentration of etomidate after stopping the infusion was consistent with a three‐compartment pharmacokinetic model. All the patients recovered within 1 hour of slopping the infusion. The use of results obtained from the first group of six patients enabled a dosage regimen to be calculated that used a two stage infusion. This regimen enabled a reduction in the lime taken to establish the appropriate degree of sedation in the second group of six patients. The two‐stage infusion technique provides a means of rapid sedation and of maintaining a suitable clinical response for the prolonged periods that may be necessary when patients are transferred to an intensive therapy unit.
Results of a feasibility trial to achieve total immobilization of patients in a neurosurgical intensive care unit with etomidate
Authors: COHN B. F. , REJGER V. , HAGENOUW‐TAAL J. C. W. , VOORMOLEN J. H. C. 
Published: June 2011

SummaryIn the intensive care unit of Leiden University Neurosurgical Department 52 critically ill patients were given continuous infusions of etomidate to achieve ‘total immobilization’. This can be defined as a state whereby there is complete elimination of all psychic, sensory and motor unrest. Etomidate administration varied from 2 hours to 25 days and dosages began at 20 μg/kg/minute and were increased to 110 μg/kg/minute according to need and indications for varying periods of time. Attempts were made to control unrest, convulsive seizure activity and raised intracranial pressure. Acceptance of artificial ventilation was achieved in most cases without muscle relaxants or morphinomimetic supplementation. Despite the long durations of administration and high doses no toxic or other detrimental side‐effects were noted. Etomidate appears to show the potential of being a very valuable addition to the neurosurgical intensive care armamentarium.
Etomidate infusion
Authors: SCORGIE B. 
Published: June 2011

SummaryEtimodate has been studied in two groups of patients. In Group 1, 50 patients received etomidate 100 μg/kg/minute with fentanyl and a muscle relaxant, ventilation being with air and oxygen (50%). The technique gave a smooth, pleasant induction with all patients asleep within 2 minutes. The incidence of pain on infusion was 6% and of myoclonus 6%. Cardiovascular changes were minimal, the most common finding being persistent tachycardia. The mean recovery time was 9.1 minutes. There was no incidence of awareness, recall, or thrombophlebitis, but a 20% incidence of nausea and vomiting. In Group 2, 20 patients received the same dosage of etomidate to supplement spinal anaesthesia for lower abdominal surgery. The technique worked most satisfactorily, with patients falling quietly to sleep within 2–3 minutes with no hiccoughs, coughing or laryngospasm. Six patients exhibited myoclonus, one being severe. In no case did myoclonus interfere with the operation. The cardiovascular system remained stable in all patients. Mean recovery time was 16.1 minutes (range 3–38 minutes). Twitching and restlessness were the main complications during recovery.
A community‐based study of sleep and behaviour problems in 12‐ to 36‐month‐old children
Authors: Hall W. A. , Scher A. , Zaidman‐Zait A. , Espezel H. , Warnock F. 
Published: June 2011

AbstractBackground  While evidence suggests sleep problems are common in young children and linked to behavioural problems, studies of toddlers are rare. This community‐based cross‐sectional study examined associations between sleep problems and daytime behaviour among 58 children aged 1 to 3 years who attended daycare centres.Methods  Mothers and daycare providers completed four and three questionnaires, respectively, about children's sleep patterns and behaviour. Two hypotheses were tested: (1) children with higher sleep problem scores would have more behavioural problems by parental and daycare provider report; (2) problematic napping behaviours would be associated with night sleep problems.Results  Mothers' reports of sleep problems were positively associated with children's behavioural problems at home and daycare providers' reports of nap problems were positively correlated with children's behavioural problems at daycare. Daycare providers' reports of children's behavioural problems at daycare were associated with maternal reports of behavioural problems. Older children in the sleep problem group had maternal reports of more behavioural problems. Daycare providers reported that children with sleep problems were less happy at daycare. Children who were happier following naps had less reported night settling difficulties. Children with difficulty settling for naps at daycare had maternal reports of more behavioural problems.Conclusions  Napping in daycare settings is an important component of toddlers' sleep. Crossover effects between children's sleep and behaviour at daycare and home indicate similarities in mothers' and daycare providers' perceptions. Findings suggest parent and daycare provider interactions include discussions about sleep problems and settling at home and in daycares. Parents and daycare providers would benefit from education about relationships between sleep and behavioural problems.