bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technology Focus: Deepwater Fields (May 2024)
Authors: Alwazzan Amir 
Published: May 2024

Without belittling our industry’s work to arrest climate change, the fact remains that relentless global efforts to secure energy during the past 4 decades have led to only a 7% reduction in the contribution of fossil fuels to the global energy supply.
In light of the historic outcomes of COP28 and the stringent agreement of 198 countries to steer away from fossil fuels, it is evident that today’s oil and gas industry is at a crossroads and in an unprecedented race with time to address the trilemma to develop a progressive multitier energy model to balance transitioning to a low-carbon industry with maintaining production and fortifying its commitment to a sustainable future.
Empowering, leveraging, and capitalizing on the current investments of our industry in the rapidly developing technologies that are revolutionizing both the renewable and fossil-fuel landscapes are exigently and prudently needed to reach this cornerstone goal. These technologies—such as carbon capture, use, and storage; winds; hydrogen; bioenergy; and geothermal—form more than 28% of the total energy consumption targeted to reduce greenhouse-gas emissions by 2050 and have a close affinity to the existing resources of the oil and gas industry.
Deepwater offshore developments have always been the forefront projects of the industry. After about a decade of fragile outlook and waning investment in these ventures, the trend is showing a dynamic rise since 2022 based on the number of sanctioned projects worldwide and the associated annual capital of more than $200 billion. This is a remarkable affirmation of the resilience of these assets and the confidence in a greener, safer, and more cost-effective future of the industry in general.
Rigorous engineering remains the key platform to accomplish the dizzying array of complex work on a daily basis and the linchpin in elevating the performance of deepwater projects from acquisition to abandonment. Opportunity still abounds for the operators of these assets to thrive and endure for the upcoming decades through advancing engineering prowess, bolstering their assets’ designs and operability, and collaborating with counterparts on potential synergies. These are prudent measures to appraise and invest in well-grounded solutions in order to harness the full potential of deepwater developments and improve their operational and overall efficiencies.
Recommended additional reading at OnePetro: www.onepetro.org.
SPE 217802 Fracturing 30,000-ft Wells in Deepwater—Planning and Execution Learnings From the Gulf of Mexico by K.F. Lizak, Shell, et al.
OTC 32808 Validation of a Completion Digital Twin Applied to Packer Setting by L.A. Oliveira, Engineering Simulation and Scientific Software, et al.
SPE 217277 Methane Recovery With Carbon Dioxide Sequestration as Hydrates in Deep Marine Environments: An Extensive Examination of Potential, Technical Advancements, and Economic Feasibility by Saket Kumar Shrivastava, SLB, et al.
Strengthening accountability for TB policy implementation in South Africa: perspectives from policymakers, civil society and communities
Authors: Westhuizen Helene-Mari , Giddy Janet , Coetzee Renier , Makanda Goodman , Tisile Phumeza , Galloway Michelle , Bunyula Siyavuya , Schoeman Ingrid , Nathavitharana Ruvandhi R. 
Published: May 2024

Abstract

Background
Translating health policy into effective implementation is a core priority for responding effectively to the TB crisis. The national TB Recovery Plan was developed in response to the negative impact that the COVID-19 pandemic had on TB care in South Africa. We aimed to explore the implementation of the TB Recovery Plan and develop recommendations for strengthening accountability for policy implementation for this and future TB policies.
Methods
We interviewed 24 participants working on or impacted by TB policy implementation in South Africa. This included perspectives from national, provincial, and local health department representatives, civil society, and community representatives. In-depth interviews were conducted in English and isiXhosa and we drew on reflexive thematic methods for analysis.
Results
Implementation of the TB Recovery Plan predominantly used a top-down approach to implementation (cascading from national policy to local implementers) but experienced bottlenecks at provincial level. Civil society organisations were concerned about the lack of provincial implementation data which impeded advocacy for better accountability. There was strong interest in community-led monitoring for local TB policy implementation from community representatives. Participants recommended broader multi-stakeholder engagement regarding TB as a public health priority and on new policies in the development and implementation phases.
Conclusion
Communities affected by TB, with the support of civil society organisations, could play a bigger role in monitoring policy implementation at local level and need to be capacitated to do this. This bottom-up approach could complement existing top-down strategies and contribute to greater accountability for TB policy implementation.
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) with amoxicillin: A case report unveiling the Flare-Up Mystery
Authors: Letón-Cabanillas Patricia , Jover-Walsh Alejandra , Aray Gabriela , Noguerado-Mellado Blanca , Rojas-Pérez-Ezquerra Patricia 
Published: May 2024

Abstract

Background: Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) is a rare cutaneous reaction associated with medication exposure, characterized by symmetrical erythema and edema in intertriginous and flexural areas, often triggered by drugs.
Case presentation: This case report describes a 40-year-old male who developed Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) after taking amoxicillin. Allergy testing revealed negative intradermal tests initially, a positive drug provocation test with amoxicillin and penicillin, suggesting cross-reactivity between the β-lactam antibiotics. Interestingly, subsequently to the last provocation the intradermal test with penicillin switched to positive showing a flare-up phenomenon.
Conclusions: The findings highlight the importance of thorough allergy evaluation, including drug provocation testing, to guide safe antibiotic treatment.
Exploration & Outcomes of Emergency Use Authorization during the
COVID-19 Pandemic in the United States
Authors: Simran Simran , Dushant Sabanis Chetan , Ramesh Joga , Kumar Sandeep 
Published: May 2024

Abstract:
The COVID-19 emergency built pressure on US regulatory bodies to unlock the optional and short pathway of approval for urgently required
pharmaceuticals to accomplish population demand for medicinal products within the shortest possible time to limit the suffering and deaths
associated with insufficiency of medicinal products in need. During the pandemic, many medicinal products got emergency use authorization
(EUA) according to the EUA guidelines provided by the US Food Drug Administration (USFDA). The requirement of abbreviated data submission
for EUA attracted many pharmaceutical companies to launch their products as investigational drugs. Clinical data collected from the population is
also permitted to get final approval. Comirnaty and Remdesivir got full approval using this regulatory tool. EUA does not ensure the existence of
the medicinal product for an extended period. Whenever the emergency is over or the products are no longer needed, the USFDA revokes those
according to their legislation. However, after Hydroxychloroquine phosphate and chloroquine sulfate were revoked due to failure to show efficacy,
it grabbed the attention of many healthcare stakeholders in the country. It demanded more transparency in the approval pathway of present EUA
guidelines. Two attributes, i.e., Current Good Manufacturing Practice exemption and expiry date extension, affect the quality of the medicinal
products used during the pandemic. The most critical product distribution data, voluntary in EUA, remarkably endorse the black-marketing and
shortage of specific COVID-19-related medicinal products in the pandemic situation. Amendments to the existing guidelines minimize the
upcoming public health risk.
Прогностична оцінка впливу хемокіну CD54 на перебіг діабетичної ретинопатії
Authors: Rybachuk O.V. 
Published: May 2024

Актуальність. Клінічні дослідження свідчать про збільшення рівня прозапальних цитокінів, хемокінів, фактора росту ендотелію судин і молекул адгезії як у системному, так і в локальному середовищі в пацієнтів з діабетичними ушкодженнями сітківки. Повідомляється про експресію судинних клітинних молекул адгезії при діабетичній ретинопатії (ДР). На сьогодні прогностична оцінка різних адгезивних молекул, зокрема молекули міжклітинної адгезії (Cluster of Differentiation, CD54), у хворих із ДР обмежена недостатньою кількістю опублікованих даних. Мета роботи полягала в розробці математичної моделі оцінки ризику прогресування діабетичної ретинопатії у хворих на цукровий діабет 2-го типу за участі CD54. Матеріали та методи. Проведено відкрите одноцентрове одномоментне вибіркове спостережне дослідження із залученням дорослих хворих на ЦД 2-го типу і ДР. Дослідження проведено в 132 осіб, з них пацієнтів із ДР було 82 (148 очей) (чоловіків — 28, жінок — 54, середній вік — 64,41 ± 1,18 року (min — 25, max — 84), середній стаж діабету — 15,54 ± 0,83 року (min — 1, max — 35), середній рівень HbA1c — 9,17 ± 0,22 % (min — 5,4, max — 16,5)). Офтальмологічне обстеження включало візометрію, периметрію, рефрактометрію, тонометрію, біомікроскопію, гоніоскопію, офтальмоскопію, оптичну когерентну томографію. Концентрацію CD54 у сироватці крові визначали імуноферментним аналізом. Статистичний аналіз включав однофакторний і багатофакторний дисперсійний аналіз і регресійний аналіз. Використовували параметричний F-критерій Фішера або непараметричний критерій Крускала — Уолліса. Адекватність розрахованої моделі оцінювалася методом побудови кривої операційних характеристик (Receiver Operating Characteristic curve — ROC-кривої) за площею під кривою (Area Under the Curve — AUC), розраховували 95% довірчий інтервал (ДІ). Відмінності вважали статистично значущими при р < 0,05. Результати. Виявлено вірогідне збільшення концентрації CD54 у сироватці крові в групі хворих на ЦД 2-го типу і ДР порівняно з контролем (р < 0,001). Показано, що при стандартизації за концентрацією CD54 у сироватці крові, рівнем HbA1c, видом цукрознижувальної терапії виявлено вірогідне зниження (p = 0,006) ризику проліферативної стадії ДР при зростанні гостроти зору на кожні 0,1 од. (СШ = 0,45 (95% ДІ 0,25–0,79)). Висновки. Чутливість розрахованої математичної моделі оцінки ризику прогресування діабетичної ретинопатії у хворих на цукровий діабет 2-го типу становить 91,7 % (95% ДІ 61,5–99,9 %), специфічність — 80,0 % (95% ДІ 68,74–88,6 %).
Cátedra Extraordinaria “José Saramago”
Authors: Espinoza Hernández Raymundo 
Published: May 2024

Breve reseña que se ofrece al lector con motivo del nombramiento de cátedras extraordinarias en la Facultad de Derecho de la UNAM, en particular, la Cátedra Extraordinaria “José Saramago” que fue recibida por el Mtro. Raymundo Espinoza Hernández. El 6 de febrero pasado, se llevó a cabo la ceremonia solemne de entrega de las Cátedras Extraordinarias por parte del Consejo Técnico de la Facultad de Derecho de la UNAM, con la presencia del Dr. Raúl Contreras Bustamante, autoridades, estudiantes y destacados miembros de la comunidad jurídica nacional. Durante este evento, se reconoció a diversos egresados y profesores por sus destacadas trayectorias en el servicio público y la academia.
Discurso pronunciado en la presentación de la Enciclopedia de los Derechos Humanos
Authors: Palomino Guerrero Margarita 
Published: May 2024

Discurso pronunciado el discurso fue leído el 20 de marzo en el Aula Magna "Jacinto Pallares". El proyecto involucra la colaboración de 172 autores, quienes desde sus respectivas áreas de especialización aportaron ensayos profundos para abordar diversas temáticas relacionadas con los Derechos Humanos. La enciclopedia comprende más de 152 textos, agrupados en seis volúmenes y clasificados en dieciocho áreas temática
derecho humano a una buena administración pública en México: una propuesta
Authors: Juárez Quezada Guadalupe 
Published: May 2024

A modo de corolario:
Un corolario, reza la definición, es una propuesta que no necesita prueba particular y se deduce con facilidad de lo demostrado previamente. Una tesis que ha sido sometida al examen cuidadoso de un sínodo y cuyo autor o autora han salido airosos de tal escrutinio, merece la promoción, la difusión, puesto que ya ha demostrado su valía.
Asimismo, un corolario supone el pináculo de un esfuerzo consistente ya realizado y qué mejor vía que una reseña crítica de las propuestas, las ideas y aportes contenidas en un trabajo de obtención de un grado académico.
Reseña del trabajo recepcional que presenta la Lic. Xel-ha Montserrat Brito Jaime, para obtener su grado de Maestría, en el posgrado de la Facultad de Derecho de la Universidad Nacional Autónoma de México; trabjo notable por su calidad, profundidad y bienhechura: tesis de maestría.
De esta manera se pretende estimular el esfuerzo de los egresados y contribuir al enriquecimiento de las ideas, los aportes y las propuestas que no deben pasar desapercibidos por nuestra comunidad.
Exploring patients’ perspectives about thalassemia and Its treatment modalities: cross sectional hospital-based study
Authors: Shaker Reem Ali , Rizij Fadhil Abduljabbar , Al-Alikhan Talib Abduljaleel Jasim 
Published: May 2024

Objective: the study was conducted to identify the potential gap in patients’ understanding, belief and behaviour towards thalassemia and its medications including iron chelation therapy (ICT).
Methods: An observational cross-sectional study performed from Feb to March 2023 on patients admitted to thalassemia centre in Najaf. The study included male and female patients diagnosed with thalassemia, taking iron chelation therapy, and accepted to participate in this study. The data were obtained by using a pretested validated questionnaire focused on sociodemographic data and 20 items used to evaluate the knowledge, attitude, and practice level (KAP).
Results: A total of 199 patients completed the study. About 73.9% of them had adequate knowledge, 78.4% showed positive attitude and 78.9% had good practice toward thalassemia and its therapy. However, 73% of them did not know that iron overload could cause diabetes and around 50% of them showed wrong belief toward importance of not missing medication doses. Additionally, third of patients experienced dose missing due to side effects. There were significant positive correlations among the total scores of patients KAP. All scores of KAP were significantly correlated with educational level while knowledge and practice scores were associated with the occupation as well as knowledge and attitude scores were also related to monthly income. Among remaining variables only male and urban residence were significantly linked to high knowledge score.
Conclusion: The study revealed overall adequate knowledge, positive attitude and good practice toward thalassemia and its therapy. Also, the study identifying specific and essential gap in patients’ awareness, belief and behaviour that need a tailored patients support and educational program.
PERLINDUNGAN HUKUM TERHADAP KERUGIAN PADA PELAKU USAHA JASA MAKE UP AKIBAT WANPRESTASI KONSUMEN
Authors: Safitri Aidila , Friatna Ida 
Published: May 2024

The Developments in the beauty industry are growing rapidly and various beauty trends are emerging as market demand increases. This article aims to examine the legal protection of business actors due to defaults committed by consumers. This type of research is a qualitative descriptive approach through case studies. Primary data was obtained from interviews with a number of makeup artists in Pidie Regency, Indonesia. While secondary data is obtained from a number of articles related to this research. The results show that legal protection of business actors is not going well, especially due to consumers who do not have good faith to pay for orders that have been ordered. For example, in the case experienced by Yolanda make up where she was supposed to get a payment of Rp. 600,000 for the engagement event according to the price list, but only received a payment of Rp. 300,000, meaning that the rest was not paid by the consumer because the reason was not as expected. In this case, normally, consumer protection has been established based on Law No.8 of 1999 concerning Consumer Protection (UUPK), but in law enforcement, disputes like this must be resolved personally by the parties, which often does not get an agreement.
Aplikasi Pupuk Kandang Ayam dan Urine Kelinci pada Pertumbuhan Bawang Merah Varietas Lembah Palu (Allium wakegi Araki)
Authors: Somba Bunga Elim , Tambing Yohanis , Acap Dendrianus Miki Nikolaus 
Published: May 2024

Kondisi tanah di sekitar Lembah Palu yang relatif kering dan kurang dapat menunjang pertumbuhan bawang merah menyebabkan produksi yang kurang maksimal, sehingga dibutuhkan tambahan zat hara dari pemupukan. Salah satu pupuk kandang yang digunakan oleh masyarakat adalah kotoran ayam. Kotoran ayam mampu menyediakan unsur hara berupa hara makro dan mikro seperti Zn, Cu, Mo, Co, Ca, Mg, dan Si, sehingga dapat meningkatkan kapasitas tukar kation (KTK) tanah. Adapun tujuan dari penelitian yaitu; 1) mengetahui pengaruh perlakuan pupuk kandang ayam dan interval pemberian POC urine kelinci; 2) mengetahui pengaruh perlakuan pupuk kandang ayam; 3) mengetahui pengaruh interval pemberian POC urine kelinci terhadap pertumbuhan dan hasil bawang merah Varietas Lembah Palu. Penelitian ini dilaksanakan di kebun akademik Fakultas Pertanian Universitas Tadulako dari bulan Februari sampai April 2023. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) faktorial dua faktor yaitu sebagai berikut: Faktor pertama adalah perbandingan pupuk kandang ayam dengan tanah terdiri 4 level yaitu: K0 = tanpa pupuk kandang ayam ( kontrol ); K1 = 1:1; K2 = 2:1; K3 = 3:1. Faktor kedua adalah interval pemberian POC urine kelinci pada konsentrasi 200 ml/liter terdiri dari 3 taraf yaitu: I1 = Setiap 3 hari 1 kali; I2 = Setiap 6 hari 1 kali; I3 = Setiap 9 hari 1 kali, sehingga terdapat 12 jumlah kombinasi. Perlakuan diulang sebanyak tiga kali sehingga mendapat 36 unit perlakuan. Masing-masing unit percobaan terdiri atas 3 polibag dan tiap polibag ditanami satu tanaman sehingga total unit percobaan yang digunakan yaitu 108 tanaman. Hasil penelitian menunjukkan bahwa tidak terdapat pengaruh interaksi antara komposisi media tanam dengan interval pemberian POC urine kelinci terhadap pertumbuhan dan hasil bawang merah . Perlakuan komposisi media tanam tidak berpengaruh pada jumlah daun, jumlah umbi, diamter umbi, dan bobot segar umbi, tetapi berpengaruh nyata pada tinggi tanaman umur 3, 4, 5, dan 6 minggu setelah tanam. Komposisi media tanam tanah berbanding pupuk kandang ayam 3:1 (K3) menghasilkan tinggi tanaman lebih tinggi dibanding perlakuan lainnya. Perlakuan interval pemberian POC urine kelinci tidak berpengaruh nyata terhadap semua parameter yang diuji.
Pengaruh Daya Tarik Wisata Terhadap Kepuasan Wisatawan Pasir Putih di Kabupaten Situbondo
Authors: Ningsih Dwi Fitria , Purwaningtyas Ayu , Nur Jannah Reni 
Published: May 2024

Pantai Pasir Putih merupakan ikon wisata di Kota Situbondo yang berlokasi di Kecamatan Bungatan. Daya tarik wisata ini berupa atraksi wisata air yang snagat popular di kalangan wisatawan. Penelitian ini bertujuan untuk memahami pengaruh daya tarik wisata terhadap kepuasan wisatawan di Pantai Pasir Putih Kabupaten Situbondo. Penelitian ini menggunakan pendekatan kuantitatif melalui observasi, wawancara dan kuesioner. Metode yang digunakan meliputi: uji validitas, uji reliabilitas, uji asumsi klasik, serta uji regresi linear sederhana, dengan teknik pengambilan sampel menggunakan Accidental Sampling. Hasil penelitian menunjukkan bahwa daya tarik wisata memiliki pengaruh signifikan terhadap variabel kepuasan wisatawan. Hal ini, dapat dibuktikan dengan hasil perhitungan menunjukkan nilai sig 0,000 < 0,05. Koefisien Determinasi menunjukkan nilai 0,586 artinya 58,6% kepuasan pengunjung dipengaruhi oleh daya tarik wisata sedangkan sisanya 41,4% dipengaruhi oleh variabel lain yang tidak diteliti.
Analysing Romanian Students’ Orientations Towards Entrepreneurship: A Survey Study in Sibiu
Authors: Popa Bianca Mădălina 
Published: May 2024

Abstract
This study aims to identify the factors that explain students’ attitudes towards entrepreneurship and their intentions to pursue entrepreneurship. The study used a quantitative methodology and collected data from 204 students through a questionnaire survey. The research hypotheses derive from established theoretical models, such as experiential learning theory, planned behaviour theory, social learning theory, and push-pull theory applied to entrepreneurship. The results show that career aspirations, exposure to entrepreneurial models, and the number of people students know as entrepreneurs play a significant role in explaining entrepreneurial attitudes and intentions. Other variables, such as academic performance, residential environment, and gender, also explain students’ entrepreneurial intentions.
Experimental Animal Models of Periodontal Diseases
Authors: Velickovic Milica , Acovic Aleksandar , Arsenijevic Aleksandar , Milovanovic Jelena , Rakic Mia , Milovanovic Marija , Kanjevac Tatjana , Arsenijevic Dragana 
Published: May 2024

Abstract
Periodontal diseases involve several conditions that are defined by pathologic loss of the periodontal ligament and alveolar bone. Periodontitis is an inflammatory disease of periodontal tissue caused by a host immune response to dysbiotic microbial biofilm whose progression associated with destruction of tooth supporting tissue is promoted by host proteinases. Periradicular periodontitis is the most commonly diagnosed disease that affects the pathology of periodontal tissue in the area of the tooth root. This disease has also been described as apical periodontitis. Several experimental models of periodontal diseases have been developed in recent years. This paper provides an overview of experimentally induced animal models of periodontal disease (periodontitis and periradicular periodontitis) and the possibility of using different experimental animals to study aspects of periodontal disease, each with advantages and disadvantage.