bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘When it floods, we work on our own’: Exploring factors influencing collective efficacy appraisals for community‐level flood measures among urban informal settlements in Suva, Fiji
Authors: Salinger Allison P. , D'Eramo Taylor , Turner Hannah , Tela Autiko , Meo‐Sewabu Litea , Delea Maryann G. , Sawailau Mere Jane , Vakarewa Isoa , Sinharoy Sheela S. ,   the RISE Consortium
Published: May 2024

AbstractMore than one billion people worldwide are living in urban informal settlements where flood risks are high. Positive collective efficacy beliefs can facilitate community‐level adaptive action. This sub‐study of the Revitalizing Informal Settlements and their Environments (RISE) trial, aimed to identify social and contextual factors influencing residents' collective efficacy appraisals about their settlement's ability to implement community‐level flood prevention, protection and response measures. Forty‐two in‐depth interviews were conducted in 10 settlements in Suva, Fiji using a photovoice methodology. Thematic analysis was used to elicit key themes, which were then interpreted and contextualized collaboratively with the local field team. The most salient influencing factors were formal leadership, shared needs or benefits, collective identity (whether via shared religion, ethnicity or regional/kinship group), past performance experiences and expectations around collective action. While the data revealed some between‐settlement variation on these factors, there was also a large degree of within‐settlement variation concerning perceptions of these factors. Community‐based flood programming should not be undertaken without first assessing the degree to which participants believe that programme objectives reflect shared needs or will yield shared benefits and whether those objectives warrant collective action according to the community's social expectations for participation and contribution.
Mechanistic Insights into Bisphenol A‐Mediated Male Infertility: Potential Role of Panax Ginseng Extract
Authors: El‐Shimi Basma I. , Mohareb Rafat M. , Ahmed Hanaa H. , Abohashem Rehab S. , Mahmoud Khaled F. , Hanna Demiana H. 
Published: May 2024

AbstractMale infertility is identified by the inability of a man to successfully impregnate his fertile female partner, even following a year of regular unprotected sexual intercourse. About half of all infertility cases are attributed to what is known as “male factor” infertility. The escalating prevalence of male infertility in the contemporary era across the globe can be largely attributed to environmental pollution, which is the common etiological factor due to the ubiquitous presence of the environmental contaminants. Bisphenol A is recognized as an endocrine‐disrupting chemical that has adverse effects on both male and female reproductive systems. On the other hand, numerous studies have demonstrated that Panax ginseng possessed the potential to improve male infertility parameters; promote spermatogenesis, recover the quality and motility of sperm and enhance testicular functions as it acted as a natural androgen supplement. The objective of this review is to offer a summary of the findings obtained from the current research data on the insult of bisphenol A (BPA) on male infertility and its supposed mode of action, as well as shed light on the potent ameliorative role of Panax ginseng extract, with a special focus on the mechanism behind its action. This review delivers a clear understanding of BPA mechanism of action on male infertility and the presumed risks deriving from its exposure. Also, this review provides evidence for the functional role of Panax ginseng extract in restoring male fertility.
Effect of Cinnamaldehyde Chalcone on Behavior in Adult Zebrafish (Danio rerio): In Silico Approach
Authors: Carneiro Romão Ivana , Costa Siqueira Sônia Maria , Amâncio Ferreira Maria Kueirislene , Wlisses da Silva Antonio , Machado Marinho Márcia , Ferreira Ribeiro Walber Henrique , de Castro Gomes Andreia Ferreira , Alencar de Menezes Jane Eire Silva , dos Santos Hélcio Silva 
Published: May 2024

AbstractThe study focuses on the anxiolytic potential of chalcone (2E,4E)‐1‐(2‐hydroxyphenyl)‐5‐phenylpenta‐2,4‐dien‐1‐one (CHALCNM) in adult zebrafish. Successfully synthesized in 58 % yield, CHALCNM demonstrated no toxicity after 96 h of exposure. In behavioral tests, CHALCNM (40 mg/kg) reduced locomotor activity and promoted less anxious behavior in zebrafish, confirmed by increased permanence in the light zone of the aquarium. Flumazenil reversed its anxiolytic effect, indicating interaction with GABAA receptors. Furthermore, CHALCNM (4 and 20 mg/kg) preserved zebrafish memory in inhibitory avoidance tests. Virtual screening and ADMET profile studies suggest high oral bioavailability, access to the CNS, favored by low topological polarity (TPSA≤75 Å2) and low incidence of hepatotoxicity, standing out as a promising pharmacological agent against the GABAergic system. In molecular coupling, CHALCNM demonstrated superior affinity to diazepam for the GABAA receptor. These results reinforce the therapeutic potential of CHALCNM in the treatment of anxiety, highlighting its possible future clinical application.
Advances in Polymeric Nanomaterial‐mediated Autophagy for Cancer Therapy
Authors: Zhao Jingyu , Hou Xiaoxue , Zhao Cuicui , Su Linzhu , Huang Fan 
Published: May 2024

AbstractAutophagy is an important biological mechanism for eukaryotic cells to regulate growth, death, and energy metabolism, and plays an important role in removing damaged organelles, misfolded or aggregated proteins, and clearing pathogens. It has been found that autophagy is closely related to cell survival and death, and is of great significance in cancerigenesis and development, playing a bidirectional role in cancer inhibition and cancer promotion. Therefore, treating cancers by regulating autophagy has attracted much attention. A large amount of research evidence indicates that polymeric nanomaterials are able to regulate cellular autophagy, and their good biocompatibility, degradability, and functionalizable modification open up a broad application prospect for improving the therapeutic effect of cancers. This review provides an overview of the research progress of polymeric nanomaterials for modulating autophagy in the treatment of cancers.
Ayurveda Rasayana Therapy (ART) leads to tumor regression and increased survival in chemo‐intolerance high‐grade stage IV follicular lymphoma: A case study
Authors: Bendale Yogesh Narayan , Birari‐Gawande Poonam , Patil Anandrao , Kadam Avinash 
Published: May 2024

Key clinical messageAyurveda Rasayana Therapy (ART) may serve as a safe and effective alternative treatment option for chemo‐intolerance high‐grade stage IV follicular lymphoma patients for increasing survival and tumor regression.AbstractFollicular lymphoma (FL), also called follicle center lymphoma/nodular lymphoma, observed in the B lymphocytes (B‐cells). Available therapeutic options for follicular lymphoma are associated with various side effects and, patients with co‐morbidities can seldom tolerate the chemotherapy regimens. Rasayana therapy not only resulted in tumor regression and improved survival but also dealt with the adverse effects of previous chemotherapy drugs. Herein, we present a case of a 74‐year‐old female diagnosed with Follicular lymphoma who had undergone three cycles of chemotherapy with unresolved disease outcome and serious adverse events. The patient refused to undergo further cycles of chemotherapy. Her family decided to start Ayurveda treatment for her as an alternative therapy for cancer care. On thorough case taking considering the Ayurveda parameters personalized Rasayana therapy as planned for the patient with an aim for improvement in Quality of Life (QoL), increasing survival, and optimizing body's immune response to fight the tumor. After treatment of 8 months, this case demonstrated partial tumor response as evidenced by PET‐CT‐scan. Quality of Life as evaluated using FACT‐G was also seen improved besides significant improvement in physical performance status evaluated using ECOG. The patient showed a survival of 3.5 years after starting Ayurveda Rasayana Therapy (ART). Rasayana therapy was well tolerated by the patient. This case report indicates the potential role of ART as a therapeutic option in geriatric cancer patients who are not eligible for cytotoxic interventions. Case warrants further systematic investigation to evaluate the potential role of ART in the treatment of geriatric cancer patients.
Kolbe Electrolysis of Long‐Chain Fatty Acids for Efficient Production of Bio‐Based Hydrophobic Paraffin Waxes
Authors: Taube Clemens , Fischer Andreas , Beyer Mario 
Published: May 2024

AbstractHerein, we present a comparative study on the Kolbe electrolysis of fatty acids. First, key parameters such as solvent composition and starting pH were briefly investigated with myristic acid (C14 : 0) as model fatty acid using a platinized titanium (Pt−Ti) anode involving the emerging liquid wax as environmentally friendly cosolvent. Second, the parameters were verified by experiments with fatty acids of different chain length (C10 : 0 to C18 : 0) which led to excellent results in the electrolysis of lauric acid (C12 : 0) with a current efficiency of 51±2 % after applying 1 FE. Comparable results (47±2 %) were obtained with a boron doped diamond anode (BDD). With current efficiencies of 45±1 % (Pt−Ti) and 46±1 % (BDD), the results were successfully transferred to an artificial fatty acid mixture as found in bio‐based coconut oil. Thus, a green and efficient method to produce bio‐based paraffin waxes on a multi‐gram scale was developed. The high hydrophobicity of the obtained waxes was validated by water contact angle measurements.
Dead Lithium in Lithium Metal Batteries: Formation, Characterization and Strategies
Authors: Jiang Yongming , Ye Fangmin 
Published: May 2024

AbstractLithium (Li) metal anode (LMA) replacing graphite anode for developing Li metal batteries (LMB) with the higher energy density has attracted much attention. However, LMA faces many issues, e. g., Li dendrites, dead Li and the side reactions, which causes the safety hazards and low coulomb efficiency (CE) of battery, therefore, LMB still cannot replace the current Li ion battery for practical use. Among those issues, dead Li is one of the decisive factors affecting the CE of LMB. To better understand dead Li, we summarize the recent work about the generation of dead Li, its impact on batteries performance, and the strategies to reuse and eliminate dead Li. Finally, the prospect of the future LMA and resultant LMB is also put forward.
Design, Synthesis, and Evaluation of BCL‐2 Targeting PROTACs
Authors: Bricelj Aleša , Dora Ng Yuen Lam , Gobec Martina , Kuchta Robert , Hu Wanyi , Javornik Špela , Rožič Miha , Gütschow Michael , Zheng Guangrong , Krönke Jan , Steinebach Christian , Sosič Izidor 
Published: May 2024

AbstractBCL‐2, a member of the BCL‐2 protein family, is an antiapoptotic factor that regulates the intrinsic pathway of apoptosis. Due to its aberrant activity, it is frequently implicated in haematopoietic cancers and represents an attractive target for the development of therapeutics that antagonize its activity. A selective BCL‐2 inhibitor, venetoclax, was approved for treating chronic lymphocytic leukaemia, acute myeloid leukemia, and other haematologic malignancies, validating BCL‐2 as an anticancer target. Since then, alternative therapeutic approaches to modulate the activity of BCL‐2 have been explored, such as antibody‐drug conjugates and proteolysis‐targeting chimeras. Despite numerous research groups focusing on developing degraders of BCL‐2 family member proteins, selective BCL‐2 PROTACs remain elusive, as disclosed compounds only show dual BCL‐xL/BCL‐2 degradation. Herein, we report our efforts to develop BCL‐2 degraders by incorporating two BCL‐2 binding moieties into chimeric compounds that aim to hijack one of three E3 ligases: CRBN, VHL, and IAPs. Even though our project did not result in obtaining a potent and selective BCL‐2 PROTAC, our research will aid in understanding the narrow chemical space of BCL‐2 degraders.
On the Electrochemical Growth of a Crystalline p–n Junction From Aqueous Solutions
Authors: Felici Roberto , Baroni Tommaso , Carlà Francesco , Cioffi Nicola , Di Benedetto Francesco , Fontanesi Claudio , Giaccherini Andrea , Giurlani Walter , Gonidec Mathieu , Lavacchi Alessandro , Berretti Enrico , Marcantelli Patrick , Montegrossi Giordano , Bonechi Marco , Picca Rosaria A. , Poggini Lorenzo , Russo Francesca , Sportelli Maria C. , Torsi Luisa , Innocenti Massimo 
Published: May 2024

AbstractOur society largely relies on inorganic semiconductor devices which are, so far, fabricated using expensive and complex processes requiring ultra‐high vacuum equipment. Here we report on the possibility of growing a p–n junction taking advantage of electrochemical processes based on the use of aqueous solutions. The growth of the junction has been carried out using the Electrochemical Atomic Layer Deposition (E‐ALD) technique, which allowed to sequentially deposit two different semiconductors, CdS and Cu2S, on an Ag(111) substrate, in a single procedure. The growth process was monitored in situ by Surface X‐Ray Diffraction (SXRD) and resulted in the fabrication of a thin double‐layer structure with a high degree of crystallographic order and a well‐defined interface. The high‐performance electrical characteristics of the device were analysed ex‐situ and show the characteristic feature of a diode.
Optimizing Photocatalytic H2 Production by Introduction of Pyrazinyls to WRCs and a New tris‐Rhenium Photosensitizer
Authors: Grundmann Nora S. , Heydari Neda , Jäggi Sarah I. , Blacque Olivier , Alberto Roger 
Published: May 2024

AbstractThe replacement of pyridyl by pyrazinyl in ligands of polypyridyl‐based cobalt water reducing catalysts (WRC) shifts reduction potentials anodically. Together with a new, trinuclear ReI photosensitizer, these WRCs show strongly improved photocatalytic performances in turnover numbers (TONs) and maximal H2 evolution rate. Depending on the catalyst structure, up to 65 kTONs at 1 μM WRC concentration were reached. Under electrocatalytic conditions in both DMF and H2O, one of the reported WRCs displays remarkable stability, producing H2 steadily over 21 and 14 d, respectively.
Arylazo‐3,5‐diphenylpyrazole Derivatives: Molecular Probes Exhibiting Reversible Light‐induced Phase Transitions for Energy Storage and Direct Photolithographic Patterning
Authors: Kumar Himanshu , Parthiban Gayathri , Velloth Archana , Saini Jyoti , De Ritobrata , Pal Santanu Kumar , Hazra Kiran Shankar , Venkataramani Sugumar 
Published: May 2024

AbstractWe report azopyrazole photoswitches decorated with variable N‐alkyl and alkoxy chains (for hydrophobic interactions) and phenyl substituents on the pyrazoles (enabling π‐π stacking), showing efficient bidirectional photoswitching and reversible light‐induced phase transition (LIPT). Extensive spectroscopic, microscopic, and diffraction studies and computations confirmed the manifestation of molecular‐level interactions and photoisomerization into macroscopic changes leading to the LIPT phenomena. Using differential scanning calorimetric (DSC) studies, the energetics associated with those accompanying processes were estimated. The long half‐lives of Z isomers, high energy contents for isomerization and phase transitions, and the stability of phases over an extended temperature range (−60 to 80 °C) make them excellent candidates for energy storage and release applications. Remarkably, the difference in the solubility of the distinct phases in one of the derivatives allowed us to utilize it as a photoresist in photolithography applications on diverse substrates.
A person‐centered perspective on employees' human resource management values and their implication for organizational commitment
Authors: Drouin‐Rousseau Sophie , Morin Alexandre J. S. , Fernet Claude , Austin Stéphanie , Fabi Bruno 
Published: May 2024

AbstractHuman resource management (HRM) practices and their associations with employees' job attitudes and behaviors are well‐established, although the psychological mechanisms underlying these associations remain unclear. Based on the ability‐motivation‐opportunity framework, we propose that employees' HRM values play a key role in these associations. Specifically, we propose that employees' perceptions of the HRM practices present in their organization will predict their HRM value profiles which, in turn, will predict their levels of commitment. Latent profile analyses revealed four profiles characterized by very low, low, moderate, and high levels of HRM values. Our results suggest that ability‐enhancing practices play an active role in employees' organizational commitment by shaping their HRM values.
Porous GaP/g‐C3N4 Photoanode for Enhanced Hydrogen Production
Authors: Yuan Hao , Zheng Maojun , Yang Ying , Gao Jiaheng , Chen Hao , Fan Yunlong , Li Yinghong , Ma Li , Wang Guohua , Shen Wenzhong 
Published: May 2024

AbstractThe g‐C3N4 decorated porous gallium phosphide have been fabricated by a facile electrophoretic deposition (EPD) process. The morphology, element composition and light absorption of the GaP/g‐C3N4 photoanode were observed using field‐emission scanning electron microscopy, X‐ray photoelectron spectroscopy, ultraviolet and visible spectrophotometer, respectively. When acting as photoanode, porous GaP/g‐C3N4 serves as a direct Z‐scheme system, where photogenerated holes in GaP are expended by electrons generated from the g‐C3N4, inhibiting the corrosion of GaP. Therefore, the porous GaP/g‐C3N4 showed a larger photocurrent density, which is 2.1 times as large as that of the porous GaP without g‐C3N4, and a more stable photocurrent density for over 10000 s (at 0 V vs RHE). Thus, this work delivers a practical way to improve the photoelectrochemical stability and property of III–V semiconductor materials, which could be used in solar energy conversion fields.
One‐Pot Synthesis of Gold Nanoparticles and Aluminum Hydroxide Hydrogels‐Based Nanocomposites with Modulated Optical Properties
Authors: Segovia Gustavo M. , Huck‐Iriart Cristián , Oestreicher Víctor , Angelomé Paula C. 
Published: May 2024

AbstractIn this work, the one‐pot synthesis of composites constituted by gold nanoparticles (AuNPs) and aluminum hydroxide hydrogels (AlHG) by employing the Epoxide Route is presented. To modulate the optical properties of the final composites, different anions (X=
,
,
and
) were used as nucleophile, complexing and growth directing agents of the AuNPs. In addition, the concentration of the reactants, e. g., the X : Cl ratio, was set in such a way to preserve the alkalization rate, the transparency of the hydrogels supporting the AuNPs, and the stability of the final composites. Consequently, the composites exhibit different plasmonic properties, resulting from the AuNPs with different sizes and morphologies, as confirmed through transmission electron microscopy, depending on the nature of the employed anion, exclusively. Furthermore, this versatile one‐pot synthesis strategy was employed to design new composites with different I : Cl ratio and synthesize stable colloidal AuNPs within an aluminum hydroxide sol (AuNP@Alsol) without adding any conventional capping agent. This AuNP@Alsol composite can be used as seed to accelerate the extremely slow AuNPs formation kinetics in AuNP@AlHG(SCN), demonstrating the potential of this synthesis method to create composites susceptible to be applied in the photonic and catalysis areas.
Synthesis and Photo/Radiation Chemical Characterization of a New Redox‐Stable Pyridine‐Triazole Ligand
Authors: Al‐Romema Abdulaziz A. , Plass Fabian , Nizovtsev Alexey V. , Kahnt Axel , Tsogoeva Svetlana B. 
Published: May 2024

AbstractPhotocatalysis using transition‐metal complexes is widely considered the future of effective and affordable clean‐air technology. In particular, redox‐stable, easily accessible ligands are decisive. Here, we report a straightforward and facile synthesis of a new highly stable 2,6‐bis(triazolyl)pyridine ligand, containing a nitrile moiety as a masked anchoring group, using copper(I)‐catalyzed azide‐alkyne cycloaddition (CuAAC) click reaction. The reported structure mimics the binding motif of uneasy to synthesize ligands. Pulse radiolysis under oxidizing and reducing conditions provided evidence for the high stability of the formed radical cation and radical anion 2,6‐di(1,2,3‐triazol‐1‐yl)‐pyridine compound, thus indicating the feasibility of utilizing this as a ligand for redox active metal complexes and the sensitization of metal‐oxide semiconductors (e. g., TiO2 nanoparticles or nanotubes).
Comparative assessment of flexural strength of monolithic zirconia with different thicknesses and two sintering techniques
Authors: Karbasian Nilofar , Fathi Amirhossein , Givehchian Pirooz , Nosouhian Saeed , Jamshidian Mohammad , Almassi Farhad , Fazeli Ali 
Published: May 2024

AbstractObjectivesThis study aimed to compare the flexural strength of monolithic zirconia with different thicknesses and two sintering techniques.Materials and MethodsThis in vitro, experimental study was conducted on 28 monolithic zirconia discs with 10 mm diameter and 0.5 (n = 14) and 1.2 mm (n = 14) thickness. Each group was divided into two subgroups (n = 7) for fast (60 min) and conventional (120 min) sintering at 1450°C. After sintering, the specimens were thermocycled and their flexural strength was measured by piston‐on‐3‐balls technique in a universal testing machine (0.5 mm/min, 1.2 mm pin diameter). Data were analyzed by the Weibull test, one‐way analysis of variance, and Tukey's test (α = .05).ResultsThe flexural strength of specimens with 1.2 mm thickness was significantly higher than that of specimens with 0.5 mm thickness (p < .05). The flexural strength of 1.2 mm/120‐min group was slightly, but not significantly, higher than that of 1.2 mm/60‐min group (p > .05). The flexural strength of 0.5 mm/120‐min group was slightly, but not significantly, higher than that of 0.5 mm/60‐min group (p > .05).ConclusionThe increase in thickness of monolithic zirconia increases its flexural strength; however, increasing the sintering time appears to have no significant effect on the flexural strength of monolithic zirconia.