bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Thieme Chemistry Journal Awardees — Where Are They Now? Macrocyclic Peptide Chemistry Inspired by Nature — From Chiral Artificial Receptors Toward Molecular Devices
Authors: Pinter Aron , Haberhauer Gebhard 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of β‐Chlorovinyl Ketones and Arenes by the Catalytic Addition of Acid Chlorides to Alkynes.
Authors: Goossen Lukas J. , Rodriguez Nuria , Goossen Kaethe 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From Ostwald Ripening to Single Chirality.
Authors: Noorduin Wim L. , Vlieg Elias , Kellogg Richard M. , Kaptein Bernard 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in the Synthesis of 5‐ and 6‐Substituted Uracil Derivatives
Authors: Bardagi Javier I. , Rossi Roberto A. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Opportunities and Challenges in Synthetic Oligosaccharide and Glycoconjugate Research
Authors: Boltje Thomas J. , Buskas Therese , Boons Geert‐Jan 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Olefin Metathesis Mediated by: Schiff Base Ru‐Alkylidenes — Ru‐Alkylidenes Bearing Unsymmetrical NHC Ligands
Authors: Monsaert Stijn , Ledoux Nele , Allaert Bart , Drozdzak Renata , van der Voort Pascal , Verpoort Francis 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intermolecular Tin—π‐Aryl Interactions: Fact or Artifact? A New Bonding Motif for Supramolecular Self‐Assembly in Organotin Compounds
Authors: Haiduc Ionel , Tiekink Edward R. T. , Zukerman‐Schpector Julio 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Macrocyclic and Supramolecular Chemistry of Organotin(IV) Compounds
Authors: Hopfl Herbert 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Heteroaromatic Compounds by Oxidative Aromatization Using an Activated Carbon/Molecular Oxygen System
Authors: Kawashita Yuka , Hayashi Masahiko 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Progress of Enantioselective Nitrile Biotransformations in Organic Synthesis
Authors: Wang Mei‐Xiang 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Practical Synthesis of Fluorine‐Containing α‐ and β‐Amino Acids: Recipes from Kiev, Ukraine
Authors: Kukhar Valery P. , Sorochinsky Alexander E. , Soloshonok Vadim A. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synergistic Interaction Between ATRP and RAFT: Taking the Best of Each World.
Authors: Kwak Yungwan , Nicolay Renaud , Matyjaszewski Krzysztof 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Living Radical Polymerization by the RAFT Process — A Second Update
Authors: Moad Graeme , Rizzardo Ezio , Thang San H. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lipidated Peptide Synthesis
Authors: Gerauer Marc , Koch Sebastian , Waldmann Herbert , Brunsveld Luc 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dimethoxy Triazine Glycosides as New Glycosyl Donors for Chemoenzymatic Synthesis of Oligosaccharides
Authors: Tanaka Tomonari , Kobayashi Atsushi , Noguchi Masato , Kimura Kei‐ichi , Watanabe Kazuhito , Shoda Shin‐ichiro 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Blocking the Anomeric Reactivity: How and Why
Authors: Nicotra Francesco , Cipolla Laura , La Ferla Barbara , Araujo Ana Catarina 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Engineering Allosteric Regulation into Biological Catalysts
Authors: Fastrez Jacques 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Copper and Zinc Binding to Amyloid‐β: Coordination, Dynamics, Aggregation, Reactivity and Metal‐Ion Transfer
Authors: Faller Peter 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Wall Teichoic Acid Function, Biosynthesis, and Inhibition
Authors: Swoboda Jonathan G. , Campbell Jennifer , Meredith Timothy C. , Walker Suzanne 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tamarind Xyloglucan: A Polysaccharide with Versatile Application Potential
Authors: Mishra Anuradha , Malhotra Annu Vij 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkaloid Biosynthesis
Authors: O'Connor Sarah E. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Well‐Defined Polypeptide‐Based Materials via the Ring‐Opening Polymerization of α‐Amino Acid N‐Carboxyanhydrides
Authors: Hadjichristidis Nikos , Iatrou Hermis , Pitsikalis Marinos , Sakellariou Georgios 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials
Authors: Iha Rhiannon K. , Wooley Karen L. , Nystroem Andreas M. , Burke Daniel J. , Kade Metthew J. , Hawker Craig J. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanisms and Principles of 1D Self‐Assembly of Peptides into β‐Sheet Tapes
Authors: Davies Robert P. W. , Aggeli Amalia , Boden Neville , McLeish Tom C. B. , Nyrkova Irena A. , Semenov Alexander N. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electron Paramagnetic Resonance Applications to Catalytic and Porous Materials
Authors: Goldfarb Daniella 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Virtual Electron Paramagnetic Resonance Laboratory: A User Guide to ab initio Modeling
Authors: Barone Vincenzo , Polimeno Antonino 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tumoral and tissue‐specific expression of the major human β‐tubulin isotypes
Authors: Leandro‐García Luis J. , Leskelä Susanna , Landa Iñigo , Montero‐Conde Cristina , López‐Jiménez Elena , Letón Rocío , Cascón Alberto , Robledo Mercedes , Rodríguez‐Antona Cristina 
Published: February 2010

AbstractThe β‐tubulins are microtubule components encoded by a multigene family, which produces slightly different proteins with complex expression patterns. Several widely used anticancer drugs base their activity on β‐tubulin binding, microtubule dynamics alteration, and cell division blockage. The expression of these drug targets in tumoral and normal cells could be of crucial importance for therapy outcome, unfortunately, the complex β‐tubulin expression patterns have been poorly characterized in human. In this study, we developed a quantitative RT‐PCR technique that accurately determines the mRNA expression of the eight human β‐tubulin isotypes, encoding class I, IIa, IIb, III, IVa, IVb, V, and VI and applied it to 21 nontumoral tissues and 79 tumor samples belonging to seven cancer types. In the nontumoral tissues, we found that, overall, TUBB (I), TUBB2C (IVb), and TUBB6 (V) were ubiquitous, TUBB1(VI) was hematopoietic cell‐specific, and TUBB2A (IIa), TUBB2B (IIb), TUBB3 (III), and TUBB4 (IVa) had high expression in brain; however, the contribution of the different isotypes to the total β‐tubulin content varied for each tissue and had a complex pattern. In tumoral tissues, most isotypes exhibited an altered expression in specific tumor types or related to tumoral characteristics. In general, TUBB3 showed a great increase in expression while TUBB6 expression was largely decreased in most tumors. Thus, normal tissues showed a complex β‐tubulin isotype distribution, which could contribute to the toxicity profile of the microtubule‐binding drugs. In addition, the specific isotypes significantly altered in tumors might represent markers for drug response. © 2010 Wiley‐Liss, Inc.
The kinetics of force‐induced cell reorganization depend on microtubules and actin
Authors: Goldyn Alexandra M. , Kaiser Peter , Spatz Joachim P. , Ballestrem Christoph , Kemkemer Ralf 
Published: February 2010

AbstractThe cytoskeleton is an important factor in the functional and structural adaption of cells to mechanical forces. In this study we investigated the impact of microtubules and the acto‐myosin machinery on the kinetics of force‐induced reorientation of NIH3T3 fibroblasts. These cells were subjected to uniaxial stretching forces that are known to induce cellular reorientation perpendicular to the stretch direction. We found that disruption of filamentous actin using cytochalasin D and latrunculin B as well as an induction of a massive unpolarized actin polymerization by jasplakinolide, inhibited the stretch‐induced reorientation. Similarly, blocking of myosin II activity abolished the stretch‐induced reorientation of cells but, interestingly, increased their motility under stretching conditions in comparison to myosin‐inhibited nonstretched cells. Investigating the contribution of microtubules to the cellular reorientation, we found that, although not playing a significant role in reorientation itself, microtubule stability had a significant impact on the kinetics of this event. Overall, we conclude that acto‐myosin, together with microtubules, regulate the kinetics of force‐induced cell reorientation. © 2010 Wiley‐Liss, Inc.
The molecular basis of frictional loads in the in vitro motility assay with applications to the study of the loaded mechanochemistry of molecular motors
Authors: Greenberg Michael J. , Moore Jeffrey R. 
Published: February 2010

AbstractMolecular motors convert chemical energy into mechanical movement, generating forces necessary to accomplish an array of cellular functions. Since molecular motors generate force, they typically work under loaded conditions where the motor mechanochemistry is altered by the presence of a load. Several biophysical techniques have been developed to study the loaded behavior and force generating capabilities of molecular motors yet most of these techniques require specialized equipment. The frictional loading assay is a modification to the in vitro motility assay that can be performed on a standard epifluorescence microscope, permitting the high‐throughput measurement of the loaded mechanochemistry of molecular motors. Here, we describe a model for the molecular basis of the frictional loading assay by modeling the load as a series of either elastic or viscoelastic elements. The model, which calculates the frictional loads imposed by different binding proteins, permits the measurement of isotonic kinetics, force‐velocity relationships, and power curves in the motility assay. We show computationally and experimentally that the frictional load imposed by alpha‐actinin, the most widely employed actin binding protein in frictional loading experiments, behaves as a viscoelastic rather than purely elastic load. As a test of the model, we examined the frictional loading behavior of rabbit skeletal muscle myosin under normal and fatigue‐like conditions using alpha‐actinin as a load. We found that, consistent with fiber studies, fatigue‐like conditions cause reductions in myosin isometric force, unloaded sliding velocity, maximal power output, and shift the load at which peak power output occurs. © 2010 Wiley‐Liss, Inc.
Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3‐kinase (PI3‐kinase) as Par3 partners by proteomic analysis
Authors: Itoh Norimichi , Nakayama Masanori , Nishimura Takashi , Fujisue Shin , Nishioka Tomoki , Watanabe Takashi , Kaibuchi Kozo 
Published: February 2010

AbstractPartition defective 3 (Par3) is involved in a variety of polarity events including establishment of apico‐basal polarity of epithelial cell, axon/dendrite specification of neurons and directional migration of cells with front‐rear polarity. Par3 is thought to regulate cell polarity as a scaffold protein by interacting with various partner proteins such as Par6, aPKC, Tiam1/2 and Numb. However, the mode of actions of Par3 in polarized migration remains largely unknown. To explore Par3 functions, we screened Par3‐interacting proteins by combining Par3 affinity column chromatography and shotgun analysis using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). We obtained about two hundred Par3‐interacting proteins from the rat brain cytosol fraction. Among them, we focused on FAK and PI3‐kinase, as both of them participate in directional cell migration. FAK associated with the PDZ domain and the coiled‐coil region of Par3 and p110 of PI3‐kinase associated with the coiled‐coil region of Par3. Par3 was partially colocalized with FAK in spreading cells. Depletion of Par3 by RNA interference inhibited adhesion‐induced activation of FAK and PI3‐kinase, and RNA interference‐resistant Par3 restored the inhibitory effects. In addition, Par3 was required for the adhesion‐induced cell spreading as well as for directional cell migration toward collagen. These results suggest that Par3 directly interacts with FAK and PI3‐kinase, enhancing their activities for polarized cell migration. © 2010 Wiley‐Liss, Inc.
How do social firms contribute to recovery from mental illness? A qualitative study
Authors: Svanberg Jenny , Gumley Andrew , Wilson Alistair 
Published: February 2010

AbstractBackground: A definition of recovery drawn from qualitative literature and the ‘consumer/survivor’ movement suggests that recovery should be seen as a way of developing satisfaction and purpose in life, whether or not symptoms of mental illness are present. A qualitative review suggested that meaningful activity may facilitate recovery by providing a sense of purpose in life. Social firms may be well placed to offer this activity due to their ethos of empowerment, their community integration and their similarity to ‘recovery‐oriented services’.Aims: The aim of this study was to explore experiences of recovery from mental illness in the context of two emerging social firms.Method: A social constructionist version of grounded theory was used to develop a model of recovery through participation in the emerging social firms. Multiple coding, triangulation and respondent validation were used to increase the rigour of study findings.Findings: A model of recovery in the context of the emerging social firms was constructed. This was influenced by characteristics such as a flexible structure, a meaningful and diverse activity, an accepting social group and an inclusive leadership.Conclusion: Social firms may provide an important model for ‘recovery‐oriented services’. Clinical, research and policy implications of findings are discussed. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:Social firms are a form of enterprise that employs people who are disadvantaged in the labour market by their disability.Social firms promote a model of community integration and empowerment for their employees.We found that individuals recovering from a mental illness experience social firms as providing a flexible environment which promotes feelings of belonging, success, competence and individuality.We interpret these findings as social firms providing secure base for recovery.
Fear of recurrence: a case report of a woman breast cancer survivor with GAD treated successfully by CBT
Authors: Montel Sébastien 
Published: February 2010

AbstractGeneral anxiety disorder (GAD) characterized by persistent, excessive and unrealistic worry about everyday things can affect everybody, including cancer patient survivor.In this paper, we present a case report of a breast cancer survivor with GAD treated by cognitive–behavioural therapy (CBT), who was excessively worried about recurrence of the disease 2 years after the end of any treatment.Cognitive reframing, associated to behavioural exposure and relaxation, were used in order to treat this woman. We describe precisely how the therapy was conducted.Results showed a substantial improvement of the fear of recurrence which ‘naturally’ extended to other stressful situations not worked during the therapy.Actually, these results are encouraging since it showed that CBT can be efficient in complicated situation involving survivor of a serious disease like cancer who additionally suffers from an anxiety disorder. It also underlines how it is important to be concerned by the distress of cancer survivors. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:

Fear of recurrence is a real problem for cancer's survivors.
Cancer's survivors affected by psychic disorders need a special psychological assistance.
CBT prove to be efficient with these patients.