bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Occurrence, Synthesis and Biosynthesis of Bacterial Heptoses
Authors: Kosma Paul 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: NADH‐Based Electrochemical Sensors
Authors: De‐los‐Santos‐Alvarez Noemi , De‐los‐Santos‐Alvarez Patricia , Lobo‐Castanon M. Jesus , Miranda‐Ordieres Arturo J. , Tunon‐Blanco Paulino 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Proton Transfers in Aromatic Systems: How Aromatic Is the Transition State?
Authors: Bernasconi Claude F. 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: NMR Spectroscopy and Ion Pairing: Measuring and Understanding How Ions Interact
Authors: Pregosin Paul S. 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Symmetry of Hydrogen Bonds in Solution
Authors: Perrin Charles L. 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Physicochemical Properties, Pharmacokinetics, and Pharmacodynamics of Intravenous Hematin
Authors: Siegert Scott W. K. , Holt Robert J. 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: TLC of Carbohydrates
Authors: Sassaki Guilherme L. , de Souza Lauro M. , Cipriani Thales R. , Iacomini Marcello 
Published: June 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Biological Profiling of Anti‐HIV Agents and Insight into CCR5 Antagonist Binding Using in silico Techniques
Authors: Carrieri Antonio , Pérez‐Nueno Violeta I. , Fano Alessandra , Pistone Carlo , Ritchie David W. , Teixidó Jordi 
Published: June 2009

AbstractMolecular requirements and determinants for efficient binding to CCR5 were interpreted by computational techniques based on comparative receptor structure modeling, advanced 3D‐QSAR, docking, and shape‐based virtual screening of commercially available entry blockers. Results of this study may be valuable for predicting new HIV entry‐blocking leads.magnified imageAcquired immune deficiency syndrome (AIDS) is responsible for more than 31 million deaths, and many more people are affected by this disease worldwide. Novel ligands that are capable of blocking virus–cell fusion are emerging as promising candidate molecules against HIV‐1 infection because they have the promise to overcome the major drawbacks of classical highly active antiretroviral (HAART) drugs. However, structure‐based design continues to be hampered owing to the paucity of experimentally determined 3D information about HIV‐1 cell‐surface co‐receptors. Using computational techniques based on comparative receptor structure modeling, advanced 3D‐QSAR, and protein–ligand docking, we present recent results that define updated molecular requirements and determinants for efficient binding of small‐molecule ligands to CCR5, a principal biological target for HIV entry blockers. These results are compared with shape‐ and property‐based virtual screening results for commercially available entry blockers, and will be valuable for predicting new HIV entry‐blocking leads.
Toward a model to compare and analyze accountability standards – the case of the UN Global Compact
Authors: Rasche Andreas 
Published: June 2009

AbstractAlthough accountability standards (e.g., the Global Reporting Initiative and SA 8000) have made their way onto the agendas of managers and researchers, a model to compare and analyze these tools in a systematic way is a conspicuous omission. This article aims to develop such a model. First, we briefly introduce the nature of accountability standards and explore commonalities and differences between them. Second, we present a model to compare and analyze these initiatives. This model allows interested parties to discuss accountability standards based on an analysis of the content of their underlying norms, the implementation processes they suggest, and their context of application. Third, we apply the model to the United Nations Global Compact. We show how this initiative differs from other standards and also discuss its strengths and weaknesses according to the outlined model. Copyright © 2009 John Wiley & Sons, Ltd and ERP Environment.
Cystein‐serine‐rich nuclear protein 1, Axud1/Csrnp1, is essential for cephalic neural progenitor proliferation and survival in zebrafish
Authors: Feijóo Carmen G. , Sarrazin Andres F. , Allende Miguel L. , Glavic Alvaro 
Published: June 2009

AbstractThe CSRNP (cystein‐serine‐rich nuclear protein) family has been conserved from Drosophila to human. Although knockout mice for each of the mammalian proteins have been generated, their function during vertebrate development has remained elusive. As an alternative to obtain insights on CSRNP's role in development, we have analysed the expression pattern and function of one member of this family, axud1, during zebrafish development. Our expression analysis indicates that axud1 is expressed from cleavage to larval stages in a dynamic pattern, becoming restricted after gastrulation to anterior regions of the developing neuraxis and later on concentrated predominantly in proliferating domains of the brain. Knockdown analysis using antisense morpholinos shows that reducing Axud1 levels impairs neural progenitor cell proliferation and survival, revealing an essential function of this gene for the growth of cephalic derivatives. The brain growth phenotypes elicited by decreasing Axud1 expression are specific and independent of anterior‐posterior patterning events, initial establishment of neural progenitors, or neural differentiation occurring in this tissue. However, Axud1 is necessary for six3.1 expression and is positively regulated by sonic hedgehog. Phylogenetic examination shows that axud1 is likely to be the ortholog of the only member of this family present in Drosophila, as well as to the previously described mouse CSRNP1 and to human AXUD1 (Axin upregulated‐1). Thus, we provide evidence as to the role of axud1 in brain growth in vertebrates. Developmental Dynamics, 2009. © 2009 Wiley‐Liss, Inc.
In vitro and in vivo differentiation of human embryonic stem cells into retina‐like organs and comparison with that from mouse pluripotent epiblast stem cells
Authors: Aoki Hitomi , Hara Akira , Niwa Masayuki , Yamada Yasuhiro , Kunisada Takahiro 
Published: June 2009

AbstractCorrectly inducing the differentiation of pluripotent hESCs to a specific lineage with high purity is highly desirable for regenerative cell therapy. Our first effort to perform in vitro differentiation of hESCs resulted in a limited recapitulation of the ocular tissue structures. When undifferentiated hESCs were placed in vivo into the ocular tissue, in this case into the vitreous cavity, 3‐dimensional retina‐like structures reminiscent of the invagination of the optic vesicle were generated. Immunohistochemical analysis confirmed the presence of both a neural retina‐like cell layer and a retinal pigmented epithelium‐like cell layer, possibly equivalent to the developing E12.5 mouse retina. Furthermore, mouse epiblast‐derived stem cells, which are reported to share some characteristics with hESCs, but not with mouse ESCs, also generated retinal anlage‐like structures in vivo. hESC‐derived retina‐like structures present a novel therapeutic possibility for retinal diseases and also provide a novel experimental system to study early human eye development. Developmental Dynamics 238:2266–2279, 2009. © 2009 Wiley‐Liss, Inc.
Crosstalk between Wnt and bone morphogenic protein signaling: A turbulent relationship
Authors: Itasaki Nobue , Hoppler Stefan 
Published: June 2009

AbstractThe Wnt and the bone morphogenic protein (BMP) pathways are evolutionarily conserved and essentially independent signaling mechanisms, which, however, often regulate similar biological processes. Wnt and BMP signaling are functionally integrated in many biological processes, such as embryonic patterning inDrosophilaand vertebrates, formation of kidney, limb, teeth and bones, maintenance of stem cells, and cancer progression. Detailed inspection of regulation in these and other tissues reveals that Wnt and BMP signaling are functionally integrated in four fundamentally different ways. The molecular mechanism evolved to mediate this integration can also be summarized in four different ways. However, a fundamental aspect of functional and mechanistic interaction between these pathways relies on tissue‐specific mechanisms, which are often not conserved and cannot be extrapolated to other tissues. Integration of the two pathways contributes toward the sophisticated means necessary for creating the complexity of our bodies and the reliable and healthy function of its tissues and organs. Developmental Dynamics 239:16–33, 2010. © 2009 Wiley‐Liss, Inc.
A 4‐year prospective study of eating disorder NOS compared with full eating disorder syndromes
Authors: Agras W. Stewart , Crow Scott , Mitchell James E. , Halmi Katherine A. , Bryson Susan 
Published: June 2009

AbstractObjective:To examine the course of Eating Disorder NOS (EDNOS) compared with anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED).Method:Prospective study of 385 participants meeting DSM‐IV criteria for AN, BN, BED, and EDNOS at three sites. Recruitment was from the community and specialty clinics. Participants were followed at 6‐month intervals during a 4‐year period using the Eating Disorder Examination as the primary assessment.Results:EDNOS remitted significantly more quickly that AN or BN but not BED. There were no differences between EDNOS and full ED syndromes, or the subtypes of EDNOS, in time to relapse following first remission. Only 18% of the EDNOS group had never had or did not develop another ED diagnosis during the study; however, this group did not differ from the remaining EDNOS group.Discussion:EDNOS appears to be a way station between full ED syndromes and recovery, and to a lesser extent from recovery or EDNOS status to a full ED. Implications for DSM‐V are examined. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2009
Anorexia nervosa: A role for L‐arginine supplementation in cardiovascular risk factors?
Authors: Vignini Arianna , D'Angelo Monica , Nanetti Laura , Camilloni Maria Angela , Cester Anna Maria , Faloia Emanuela , Salvolini Eleonora , Mazzanti Laura 
Published: June 2009

AbstractObjective:The aim of the present study was to evaluate the effects of a short‐term oral L‐arginine treatment on platelet NO production, intracellular calcium concentration, iNOS and eNOS expression, in AN patients.Method:Forty outpatients belonging to restricting subtype and 40 normal participants age and sex matched were enrolled in the study.Results:NO production was significantly elevated in the platelets from AN patients compared with controls while [Ca2+]i was significantly decreased in patients with respect to controls. Western blot analysis demonstrated that iNOS isoform was more pronounced in the cell lysates from AN patients than controls. After supplementation with L‐arginine, both NO production and [Ca2+]i seem to return to control levels, suggesting a probable recovery of their metabolisms. The same was found after western blot analysis of NOS expression.Discussion:The results here proposed can be considered highly indicative of a positive effect of L‐arginine supplementation on platelet NO production in AN patients. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010
Therapeutic writing as an intervention for symptoms of bulimia nervosa: Effects and mechanism of change
Authors: Johnston Olwyn , Startup Helen , Lavender Anna , Godfrey Emma , Schmidt Ulrike 
Published: June 2009

AbstractObjective:This study explored the effects on bulimic symptomatology of a writing task intended to reduce emotional avoidance.Method:Eighty individuals reporting symptoms of bulimia completed, by e‐mail, a therapeutic or control writing task. Participants completed questionnaires on bulimic symptoms, mood, and potential moderating and mediating factors, and were followed up after 4 and 8 weeks. Writing content was explored using a word count package and qualitative framework analysis.Results:Bulimic symptoms decreased in both groups, although in both groups the number of participants who improved was approximately equal to the number who did not improve. Symptom decreases were associated with increases in perceived mood regulation abilities, and decreases in negative beliefs about emotions. Participants preferred internet delivery to face to face discussion.Discussion:For individuals experiencing symptoms of bulimia, the effects of therapeutic writing did not differ significantly from effects of a control writing task. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010
Mortality and predictors of death in a cohort of patients presenting to an eating disorders service
Authors: Button Eric J. , Chadalavada Bhanu , Palmer Robert L. 
Published: June 2009

AbstractObjective:The main aim was to investigate mortality across the spectrum of eating disorders presenting to a specialized service for adults in the UK. A secondary aim was to explore whether any clinical and demographic factors may be associated with increased risk.Method:We conducted a “tracing” study of 1,892 patients assessed by the Service between 1992 and 2004. We used the Office of National Statistics to identify all deaths recorded up to August 2007. We also compared deceased patients with matched controls in terms of a number of clinical and demographic variables at initial presentation to the service.Results:Anorexia nervosa had a ten‐fold increased risk of early death, but there was also evidence of increased risk in other groups of patients, including eating disorder not otherwise specified. A number of clinical factors predicted increased mortality risk, especially very low body mass index and the presence of alcohol misuse.Discussion:The study confirms previous evidence of a markedly increased mortality risk for anorexia nervosa, but also suggests that the risk is not confined to this eating disorder and that greater attention needs to be focused on wider psychiatric comorbidity. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2010
Coupled analysis of electromagnetic wave and heat conduction with rotational motion of heated target and temperature‐dependent complex permittivity
Authors: Okamoto Yoshifumi , Himeno Ryutaro , Ushida Kiminori , Ahagon Akira , Fujiwara Koji 
Published: June 2009

AbstractIn order to evaluate the heated process of the target, S parameter, and initial design of cavity size in the furnaces for dielectric heating such as microwave ovens, the coupled analysis of electromagnetic wave and heat conduction (EM‐HC coupled analysis) is a useful tool for practical design. In this paper, valuable EM‐HC coupled analysis with rotational motion of heated target such as turntable and temperature‐dependent complex permittivity by using edge‐based finite element method is proposed. As a result of useful investigation of the proposed method, the effectiveness in tracing the detailed temperature rise of dielectric target is demonstrated. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(1): 9–19, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20810
PI control adjusted by GA for ultrasonic motor
Authors: Tanaka Kanya , Wakasa Yuji , Akashi Takuya , Oka Masato 
Published: June 2009

AbstractThis paper proposes a PI control method adjusted by a genetic algorithm (GA) for an ultrasonic motor (USM). In the proposed method, proportional and integral gains are adjusted using a GA in order to compensate the characteristic variations of the plant. The effectiveness of the proposed method is confirmed by experiments. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(1): 59–65, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20842
A new current balancer in single‐phase three‐wire secondary distribution feeders using the correlation coefficients
Authors: Tanaka Toshihiko , Fukui Hirokazu , Hiraki Eiji , Watanabe Shuuji , Fukuma Shinji 
Published: June 2009

AbstractThis paper proposes a new current balancer in single‐phase three‐wire secondary distribution systems using the correlation coefficients. The components of the load currents correlative to the primary side voltage waveform, which correspond to the active currents, are detected in each feeder, then the nonactive and unbalanced‐active components are compensated on the source side. The balanced currents with unity power factor are obtained in each feeder. The basic principle of the proposed method is discussed in detail, and then confirmed by digital computer simulation. A prototype experimental system is constructed and tested. Experimental results demonstrate that the balanced source currents with unity power factor are obtained in spite of unbalanced load currents. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(1): 50–58, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20843
Rotor speed detection method for vector control of induction motor without speed sensor utilizing slot harmonics
Authors: Kiyotake Hirofumi , Shinohara Katsuji , Yamamoto Kichiro 
Published: June 2009

AbstractSpeed sensorless vector controlled induction motor drives are the standard choice in many industrial applications, but this can hardly control torque and rotor speed at low speed. Recently, a method based on high‐frequency signal injection has been studied. This paper presents a method for suppressing the effects of the saturation saliency by using a high‐pass filter, and a new approach to estimate the rotor speed. The effectiveness of these methods is demonstrated through experimental results showing both good suppression of saturation harmonics and good sensorless speed control at low speed. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 169(1): 41–49, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20847
Participation of experts and non‐experts in a sustainability assessment of mobility
Authors: Whitmarsh Lorraine , Swartling Åsa Gerger , Jäger Jill 
Published: June 2009

AbstractThe complexity, ambiguity and subjectivity that surround persistent problems of unsustainability, such as mobility, highlight the importance of stakeholder engagement in both knowledge production and policy development. This paper reports on research within the EU‐funded MATISSE project to develop tools and methods for Integrated Sustainability Assessment (ISA), a novel interdisciplinary and participatory approach to sustainability strategy development. Two different methods – expert focus groups and citizen deliberative workshops – were employed to elicit knowledge and preferences of European stakeholders in respect of sustainable mobility. Findings from these exercises indicate areas of both convergence and divergence in the visions of sustainable mobility futures depicted by different stakeholder groups. Stakeholders agreed on the need to address problems of unsustainability in the transport sector, and identified broadly similar environmental, social and economic criteria for sustainable transport. Amenity of transport was more important for citizens, while experts focussed on pragmatic and technological issues. Both groups favoured modal shift and novel technologies, and citizens also supported demand reduction measures and choices; however, a range of barriers to achieving sustainable mobility was also identified by participants. Stakeholder feedback suggests the process was valuable and acted as a forum for social learning and the co‐production of knowledge by citizens and experts, while at the same time empowering these groups to participate in an important social issue such as transport. The value and limitations of these methods for ISA are discussed and avenues for further research proposed. Copyright © 2009 John Wiley & Sons, Ltd and ERP Environment.
DC‐induced CD8+ T‐cell response is inhibited by MHC class II‐dependent DX5+CD4+ Treg
Authors: Han Wanda G. H. , Schuurhuis Danita H. , Fu Nathalie , Camps Marcel , van Duivenvoorde Leonie M. , Louis‐Plence Pascale , Franken Kees L. M. C. , Huizinga Tom W. J. , Melief Cornelis J. M. , Toes René E. M. , Ossendorp Ferry 
Published: June 2009

AbstractCD4+ T cells are important for CD8+ T‐cell priming by providing cognate signals for DC maturation. We analyzed the capacity of CD4+ T cells to influence CD8+ T‐cell responses induced by activated DC. Surprisingly, mice depleted for CD4+ cells were able to generate stronger antigen‐specific CD8+ T‐cell responses after DC vaccination than non‐depleted mice. The same observation was made when mice were vaccinated with MHC class II−/− DC, indicating the presence of a MHC class II‐dependent CD4+ T‐cell population inhibiting CD8+ T‐cell responses. Recently we described the expansion of DX5+CD4+ T cells, a T‐cell population displaying immune regulatory properties, upon vaccination with DC. Intriguingly, we now observe an inverse correlation between CD8+ T‐cell induction and expansion of DX5+CD4+ T cells as the latter cells did not expand after vaccination with MHC class II−/− DC. In vitro, DX5+CD4+ T cells were able to limit proliferation, modulate cytokine production and induce Foxp3+ expression in OVA‐specific CD8+ T cells. Together, our data show an inhibitory role of CD4+ T cells on the induction of CD8+ T‐cell responses by activated DC and indicate the involvement of DX5+CD4+, but not CD4+CD25+, T cells in this process.