bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mayo adhesive probability score predicts postoperative fever and sepsis in retrograde intrarenal surgery
Authors: Hsieh Tsung-Yi , Chang Shang-Jen , Chueh Jeff Shih-Chieh , Lee Yuan-Ju 
Published: May 2024

AbstractInfectious complications are among the most common and potentially life-threatening morbidities of retrograde intrarenal surgery (RIRS). Few predictive tools on these complications include radiological signs. The Mayo adhesive probability (MAP) score is an image-based scoring system that incorporates two radiological signs: perinephric fat stranding and perinephric fat thickness. Previous studies have suggested an association between these signs and febrile urinary tract infection (UTI) following lithotripsy. This study aimed to evaluate the predictive factors, including the MAP score, for post-RIRS fever and sepsis. A total of 260 patients who underwent 306 RIRS between October 2019 to December 2023 due to renal or upper ureteral stones were included in this retrospective study. Patient demographics, perioperative characteristics, stone factors, radiological signs, and MAP scores were recorded. Multivariate logistic regression analysis was used to evaluate the risk factors associated with postoperative fever and sepsis. Postoperative fever and sepsis occurred in 20.8% and 8.5% of the patients, respectively. On multivariate analysis, female gender, history of recurrent UTI, larger maximal stone diameter, and higher MAP score were independent risk factors for postoperative fever and sepsis. Identifying the risk factors for post-RIRS infectious complications is imperative to providing the proper perioperative management. The MAP score is a promising, easily calculated, image-based scoring system that predicts post-RIRS fever and sepsis.
Effect of environmental exposome and influenza infection on febrile seizure in children over 22 years: a time series analysis
Authors: Jiang Xiaoting , Li Conglu , Yue Qianying , Wei Yuchen , Wang Yawen , Lao Xiang Qian , Lin Guozhang , Chong Ka Chun 
Published: May 2024

AbstractFebrile seizures are convulsions predominately occurring in young children. The effects of various exposomes, including influenza infection and external environmental factors, on febrile seizures have not been well-studied. In this study, we elucidated the relationships between ambient temperature, air pollutants, influenza infection, and febrile seizures using 22-year territory-wide hospitalization data in Hong Kong. The aggregated data were matched with the meteorological records and air pollutant concentrations. All-type and type-specific influenza-like illness positive (ILI+) rates were used as proxies for influenza activity. Distributed lag non-linear model in conjunction with the quasi-poisson generalized additive model was used to examine the associations of interest. According to the results, all-type influenza infections were significantly associated with an increased risk of hospital admissions for febrile seizures (cumulative adjusted relative risk [ARR] = 1.59 at 95th percentile vs. 0; 95% CI, 1.51–1.68). The effect of ILI + A/H3N2 on febrile seizure was more pronounced than other type-specific ILI + rates. A low mean ambient temperature was identified as a significant risk factor for febrile seizures (cumulative ARR = 1.50 at 5th percentile vs. median; 95% CI, 1.35–1.66), while the redox-weighted oxidant capacity and sulfur dioxide were not associated with febrile seizures. In conclusion, our study underscores that influenza infections and exposure to cold conditions were related to an increased risk of febrile seizures in children. Thus, we advocate for influenza vaccination before the onset of the cold season for children to mitigate the burden of febrile seizures.
Methodological influence on detecting temperature effects on growth variability in juvenile Atlantic salmon
Authors: Matte Jean-Michel O. , Dauphin Guillaume J.R. , St-Hilaire André , Gillis Carole-Anne , Bergeron Normand E. , Breau Cindy 
Published: May 2024

AbstractIn the context of warming freshwater habitats, protection of Atlantic salmon populations requires an understanding of the effects of temperature on somatic growth during the juvenile life stage. However, quantifying the effect of temperature on growth is challenging given differences among methodologies, metrics of growth, and their underlying assumptions. Using short term studies (2000–2002) in two Canadian populations of wild Atlantic salmon (Margaree and Miramichi rivers), we investigate whether different hierarchical modeling approaches influence the derivation of temperature-growth relationships, by contrasting seasonal growth trajectories (von Bertalanffy; VBGF) to size-at-age data models built with instantaneous growth rates. Size-at-age data analysed seasonally with the VBGF framework failed to detect an effect of temperature, whereas instantaneous growth rates from the same dataset were strongly related to temperature metrics. However, instantaneous growth rates cannot be used to extrapolate predictions into meaningful metrics for fisheries management (e.g., size at the end of the growing season). Nevertheless, we show that size at the end of the growing season can be predicted with VBGF models accounting for site-level variation, which in turn are related to temperature metrics, as observed for instantaneous growth rates. Taken together, these results show that combining these two approaches (size-at-age, growth rates) can circumvent their intrinsic drawbacks and reveal essential ecological patterns that may otherwise remain undetected. In cases where instantaneous growth rates are not available, relating predicted size-at-age from hierarchical VBGF to temperature provides an interesting alternative for detecting subtle environmental effects, even if the VBGF parameters or its residuals are unrelated to temperature metrics.
Inability to Work Fulltime and the Association with Paid Employment One Year After the Work Disability Assessment: A Longitudinal Register-Based Cohort Study
Authors: Boersema Henk-Jan , Hoekstra Tialda , van Ooijen Raun , van Zon Sander K. R. , Abma Femke I. , Brouwer Sandra 
Published: May 2024

Abstract
Objectives
Disability benefit applicants with residual work capacity are often not able to work fulltime. In Dutch work disability benefit assessments, the inability to work fulltime is an important outcome, indicating the number of hours the applicant can sustain working activities per day. This study aims to gain insight into the association between inability to work fulltime and having paid employment 1 year after the assessment.

Methods
The study is a longitudinal register-based cohort study of work disability applicants who were granted a partial disability benefit (n = 8300). Multivariable logistic regression analyses were conducted to study the association between inability to work fulltime and having paid employment 1 year after the assessment, separately for working and non-working applicants.

Results
For disability benefit applicants, whether working (31.9%) or not working (68.1%) at the time of the disability assessment, there was generally no association between inability to work fulltime and having paid employment 1 year later. However, for working applicants diagnosed with a musculoskeletal disease or cancer, inability to work fulltime was positively and negatively associated with having paid employment, respectively. For non-working applicants with a respiratory disease or with multimorbidity, inability to work fulltime was negatively associated with paid employment.

Conclusions
Inability to work fulltime has limited association with paid employment 1 year after the disability benefit assessment, regardless of the working status at the time of assessment. However, within certain disease groups, inability to work fulltime can either increase or decrease the odds of having paid employment after the assessment.
Primal Subgradient Methods with Predefined Step Sizes
Authors: Nesterov Yurii 
Published: May 2024

AbstractIn this paper, we suggest a new framework for analyzing primal subgradient methods for nonsmooth convex optimization problems. We show that the classical step-size rules, based on normalization of subgradient, or on knowledge of the optimal value of the objective function, need corrections when they are applied to optimization problems with constraints. Their proper modifications allow a significant acceleration of these schemes when the objective function has favorable properties (smoothness, strong convexity). We show how the new methods can be used for solving optimization problems with functional constraints with a possibility to approximate the optimal Lagrange multipliers. One of our primal-dual methods works also for unbounded feasible set.
Sinorhizobium fredii HH103 flgJ is a flagellar gene induced by genistein in a NodD1- and TtsI- dependent manner
Authors: Navarro-Gómez Pilar , Alías-Villegas Cynthia , Jiménez-Guerrero Irene , Fuentes-Romero Francisco , López-Baena Francisco-Javier , Acosta-Jurado Sebastián , Vinardell José-María 
Published: May 2024

Abstract
Background and aims
Sinorhizobium fredii HH103 is a broad host-range rhizobial strain able to induce the formation of nitrogen-fixing nodules in dozens of legumes, including soybean. S. fredii HH103 exhibits genistein-induced surface motility. The aim of this work has been to determine whether the flgJ gene, which is inducible by genistein and codes for a flagellar protein, is involved in this motility and is relevant for symbiosis with soybean.

Methods
We have generated two independent mutants in the flgJ gene of HH103 and analysed their phenotypes in motility, exopolysaccharide production, biofilm formation, soybean root colonization, symbiosis with soybean, and secretion of effector proteins. We have also further studied the regulation of the expression of flgJ.

Results
We show that the expression of flgJ is driven by a tts box previously not detected, which accounts for its induction by flavonoids and the NodD1 and TtsI transcriptional activators. Inactivation of flgJ led to severe impairments in bacterial motility (swimming and genistein-induced surface motility) as well as to a significant reduction in symbiotic performance with soybean when bacteria are not directly inoculated onto the seedling roots. However, the absence of a functional FlgJ protein did not affect the bacterial ability to colonize soybean roots.

Conclusion
The flgJ gene of S. fredii HH103 connects the nod regulon with the genistein-induced surface motility exhibited by this rhizobial strain.
Ultrasonographic, endoscopic and radiographic examinations of the dromedary mammary glands and teats
Authors: Annika Müller , Wernery Ulrich , Kinne Jörg , Nagy Peter , Juhasz Judit , De Bont Matthew , Booth Claire , Azmanis Panagiotis , Wittek Thomas 
Published: May 2024

AbstractThe aim of the present study was to examine the mammary gland of dromedary camels using ultrasonography, endoscopy and radiography. These techniques are easy to perform in the field and feasible to diagnose pathological conditions of the mammary gland. Udders of 49 slaughtered and 26 adult dromedary camels submitted for necropsy were used for the examinations. Additionally, 11 lactating female dromedary camels were selected for the ultrasonographic udder examination. The transition from the milk ducts into the udder cistern, the teat cistern and the teat canals were examined in individual udders. Teat cistern length, teat end width, teat wall thickness, teat cistern width and middle cistern wall thickness were measured using ultrasonography. The measurements resulted in mean values of the teat cistern length of 37.3 mm, the teat end width of 2.0 mm, the teat wall thickness of 4.4 mm, the teat cistern width of 8.2 mm and the cistern wall thickness of 3.5 mm. The teat wall was differentiated into three layers, a hyperechoic outer layer, a hypoechoic middle layer and a hyperechoic inner layer. The mid cistern wall was hyperechoic. Endoscopic examination is an easy to perform and practicable method for examining the inner structures of the teats of dead animals; however, the feasibility has not been shown in lactating animals yet. Ring-like folds were present in the teat cistern, which protruded horizontally into the lumen. It was also possible to visualize the branchlike transition of the teat cistern into the larger milk ducts. Radiographic examination using barium sulfate contrast medium showed that the teat cistern ends in a network of initially wide but branching and narrowing milk ducts. The two teat canals and cisterns are completely independent of each other and there is no communication between the glandular tissue of the two canals and cisterns.
(A)voiding misdiagnosis: prediction of detrusor underactivity vs. bladder outlet obstruction using pre-urodynamic nomogram in male patients with LUTS
Authors: Garbas Karolina , Zapała Łukasz , Ślusarczyk Aleksander , Piecha Tomasz , Gwara Piotr , Żuk-Łapan Aleksandra , Piekarczyk Hanna , Zapała Piotr , Radziszewski Piotr 
Published: May 2024

Abstract
Purpose
Our study aimed to develop a noninvasive model using a combination of the set of clinical data and uroflowmetry (UFL) to differentiate between detrusor underactivity (DU) and bladder outlet obstruction (BOO) in non-neurogenic male patients with lower urinary tract symptoms (LUTS).

Methods
Data from 229 men with LUTS, diagnosed with DU or BOO on a pressure-flow study (PFS), were retrospectively analyzed, including medical history, Core Lower Urinary Tract Symptoms score (CLSS) questionnaire, UFL and PFS. Uni- and multivariate logistic regression were utilized for the prediction analyses.

Results
Of the cohort, 128 (55.9%) patients were diagnosed with DU. A multivariate logistic regression analysis identified less prevalent nocturia (OR 0.27, p < 0.002), more prevalent intermittency (OR 2.33, p = 0.03), less prevalent weak stream (OR 0.14, p = 0.0004), lower straining points in CLSS (OR 0.67, p = 0.02), higher slow stream points in CLSS (OR 1.81, p = 0.002), higher incomplete emptying points in CLSS (OR 1.31, p < 0.02), lower PVR ratio (OR 0.20, p = 0.03), and present features of fluctuating (OR 2.00, p = 0.05), fluctuating-intermittent (OR 3.09, p < 0.006), and intermittent (OR 8.11, p = 0.076) UFL curve shapes as independent predictors of DU. The above prediction model demonstrated satisfactory accuracy (c-index of 0.783).

Conclusion
Our 10-factor model provides a noninvasive approach to differentiate DU from BOO in male patients with non-neurogenic LUTS, offering a valuable alternative to invasive PFS.
Delirium care in hospitals in Ireland on World Delirium Awareness Day 2023
Authors: Azizi Zahra , O’Regan Niamh , Dukelow Tim , Bohane Teresa , Harkin Eithne , Donnellan Christina , Carroll Ida , Costello Maria , O’Reilly Susan , Noonan Claire , Walsh Erica , Timmons Suzanne 
Published: May 2024

Abstract
Background
Acute, transient, but sometimes persistent, delirium is characterized by a sharp disruption in attention, consciousness, and cognitive function, and can be caused by many medications and disorders. Delirium occurrence and negative consequences, such as falls and functional decline, can be decreased with multifactorial prevention and timely detection.

Aims
To describe current clinical practice in relation to the prevention, assessment, and management of delirium in Irish hospitals; awareness-raising and educational activities; and barriers to good practice.

Methods
On World Delirium Awareness Day (15th March 2023), a global survey was conducted of delirium prevalence and care. A senior clinical staff member on each participating ward reported on delirium prevalence at 8AM and 8PM, and on usual ward practice; this data was entered into an online survey by a data collector (typically a clinician from the site, visiting several wards to record data). This study reports data from Irish hospitals.

Results
In total, 132 wards from 15 hospitals across Ireland participated. Almost 60% of wards used ‘personal judgment’ for delirium assessment. Having at least one delirium training session in the preceding year was associated with greater use of a formal assessment tool (60.3% versus 18.8%; p < 0.001). Wards reported staff training/education as the main priority to improve care, but 72.7% of wards identified insufficient time to train staff as a key barrier.

Conclusions
Clinical practice related to delirium care requires improvement. Awareness raising and staff training require more focus and time in busy clinical settings.
Discharged from the emergency department following hospital-presented self-harm: referral patterns and risk of repeated self-harm
Authors: Cully Grace , Russell Vincent , Joyce Mary , Corcoran Paul , Daly Caroline , Griffin Eve 
Published: May 2024

Abstract
Background
Presentation to the emergency department (ED) with self-harm provides an important opportunity for intervention.

Aims
To investigate characteristics and self-harm repetition risk of those discharged from the ED without a referral for mental health–related aftercare.

Method
Data on consecutive self-harm presentations to EDs for the years 2013–2019 (n = 55,770) were obtained from the National Self-Harm Registry Ireland. Multilevel Poisson and Cox regression models were estimated.

Results
Half of the self-harm presenters were discharged from the ED (49.8%) and almost half of them did not receive a mental health–related referral (46.8%). Receipt of a psychosocial assessment was associated with a 50% reduced risk of non-referral (IRR 0.54; 95% CI 0.51–0.57). Non-referral was also less likely for young people (< 18 years), presentations involving attempted hanging, persons with previous self-harm presentations, and in the latter half of the study period (2017–2019 vs. 2013–2016), but was more likely for those brought by ambulance, presenting outside 9 am–5 pm and admitted to an ED medical assessment unit. Of those not referred, 19.3% had a repeat presentation within 12 months, compared to 22.4% of those referred. No difference in repetition risk between these two groups was evident in adjusted analyses. Self-harm history had the strongest association with repetition, with highest risk among individuals with four or more previous presentations (HR 9.30, 95% CI 8.14–10.62).

Conclusions
The findings underline the importance of assessing all individuals who present with self-harm and highlight the need for comprehensively resourced 24hr services providing mental health care in the ED.
Herausforderungen der Mobilitätsförderung in Pflegeeinrichtungen
Authors: Otto Ann-Kathrin , Saß Eileen , Vogel Oliver , Wollesen Bettina 
Published: May 2024

Zusammenfassung
Hintergrund
Die Mobilitätsförderung von Personen mit Pflegebedarf nimmt aufgrund der präventiven und kurativen Effekte in Pflegeeinrichtungen einen hohen Stellenwert ein. Ziel dieser Studie ist es, den Umfang der Förderung von Mobilität in deutschen Pflegeeinrichtungen und die Auswirkungen der COVID-19-Pandemie aufzuzeigen. Darüber hinaus wird der Einfluss der Anzahl der Pflegeplätze (AP) sowie die Höhe des monatlichen Eigenanteils (EA) in die Untersuchung integriert.

Methodik
In der zweistufigen explorativen Studie wurden Einrichtungs- und Pflegedienstleitungen (N = 16) via Telefoninterviews zur Mobilität der Bewohnenden zur Zeit der COVID-19-Pandemie befragt. Es erfolgte eine qualitative Inhaltsanalyse sowie eine Quantifizierung der Aussagen mit anschließender Pearson-Korrelationsanalyse.

Ergebnisse
Die Förderung von Mobilität erfolgte in den Einrichtungen am häufigsten durch das Pflegepersonal oder externe Gesundheitsdienstleister in Form von Bewegungsangeboten. Die Mobilitätsförderung steigt mit der AP (r = 0,502; p = 0,057) sowie dem EA (r = 0,788; p < 0,001). Die Mobilitätsförderung aller befragten Einrichtungen reduzierte sich während der COVID-19-Pandemie durch z. B. Isolation und Angst. Die qualitative Analyse zeigte, dass die Förderung von Mobilität in den Einrichtungen am häufigsten durch das Pflegepersonal oder externe Physiotherapeut*innen in Form von Bewegungsangeboten erfolgte.

Diskussion
Der Fachkräftemangel, fehlende Finanzierungsmöglichkeiten sowie eine andere Prioritätensetzung könnten in Einrichtungen mit geringer AP oder EA Hindernisse zur Mobilitätsförderung darstellen. Einflüsse der COVID-19-Pandemie führten z. B. zur Isolation und verhinderten bei allen Einrichtungen die Durchführung von Mobilitätsmaßnahmen. Digitale Angebote, Leitlinien zur Gestaltung mobilitätsfördernder Maßnahmen zu Pandemiezeiten sowie politische Maßnahmen zur Reduktion des Fachkräftemangels könnten zentrale Lösungsansätze sein.
Investigation of the pathogen-specific antibody response in periprosthetic joint infection
Authors: Janz Viktor , Rakow Anastasia , Schröder Leonie , Hofer André , Wiebe Sergej , Schoon Janosch , Weiss Stefan , Bröker Barbara M. , Wassilew Georgi I. , Raafat Dina 
Published: May 2024

Abstract
Purpose
Periprosthetic joint infections (PJIs) are a very demanding complication of arthroplasty. Diagnosis of PJI and pathogen identification pose considerable challenges in clinical practice. We hypothesized that the pathogen-specific immune response to PJI reflects the infection process, provides clinically relevant information on disease course, and has the potential to further optimize antimicrobial therapy.

Methods
We conducted a prospective matched cohort pilot study with 13 patients undergoing two-stage septic revision arthroplasty (PJI patients) between 06/2020 and 06/2021, as well as 11 control patients undergoing one-stage aseptic revision arthroplasty (Non-PJI patients). Pre-, intra- and postoperative serum samples were collected at standardized time points. We developed a custom Luminex®-based quantitative bead-based suspension array (Infection Array; IA), and used it for simultaneous measurement of antibody specificities against 32 pathogens commonly associated with PJI in 267 serum samples.

Results
The IA was able to trace the dynamics of the pathogen-specific humoral immune response in all patients against PJI-related pathogens, prominently coagulase-negative staphylococci and streptococci. Pathogen-specific serum antibody titers declined in 62% of PJI patients over the course of treatment, while no changes in antibody titers were observed in 82% of Non-PJI patients during this study. Our serological data strongly suggested that antibody signatures reflect an immune response to microbial invasion.

Conclusion
Our results provide insights into the pathophysiology of PJI and information on the individual disease courses. The IA is therefore a promising and novel serological tool of high resolution for monitoring the immunoproteomic footprints of infectious pathogens in the course of PJI.
The influences of Thai divination on Cambodian fortune-telling practice
Authors: Jiaviriyaboonya Poonnatree 
Published: May 2024

Abstract
The Khmer Rouge period had a hugely negative impact on the knowledge and practices of Khmer divination. At present, Khmer divination and astrology has been revitalized with many forms of it being embedded in people’s everyday lives in both rural and urban settings, such as in the capital Phnom Penh. With the re-emergence of numerological fortune-telling, Khmer practitioners are now turning to Thai numerological books, such as ‘Patithin Neung Roi Pee (100-year calendar)’, ‘Tamra Phromachati’, and ‘Tamra Plu Luang’ to supplement the diminished body of traditional Khmer knowledge that survived the war. This paper aims to explore how Cambodia divinatory and astrologicalauthority have been revitalized and reinvented through that of their Thai counterparts within the flows of globalization and modernity.