bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eksplorasi Professional Learning Community (PLC) pada Dimensi Supportive and Leadership di Sekolah Dasar Program Khusus
Authors: Ardhi Muh. Waskito , Praptiwi Erma , Ernawati Dwi 
Published: May 2024

Supportive leadership in the teacher community in schools has an important meaning for the formation of professional learning communities. The purpose of this study was to explore the experiences of teachers involved in the application of PLCs which were limited to the dimensions of Supportive and shared leadership in Special Program-based primary schools. The research approach used case studies. The source of data in this study was 15 teachers in 2 special program elementary schools located in Boyolali district, Central Java, Indonesia. Data collection using semi-structured interviews. The data in this study was analyzed using thematic analysis techniques. The results of this study found that there are 11 themes that describe the dimensions of supportive and leadership, namely (1) types of leadership support (2) school leadership strategies (3) forms of teacher leadership (4) means of leadership guidance (5) forms of implementing decisions (6) leadership attitudes (7) evaluation of decision implementation (8) teacher collaboration (9) collaboration media (10) forms of teacher responsibility to the community and (11) leadership roles.
Impacto de la integración de tecnologías móviles en el aprendizaje: Un estudio longitudinal en educación primaria
Authors: González Castro Andrés Vinicio 
Published: May 2024

El presente estudio longitudinal examinó el impacto de la integración de tecnologías móviles en el aprendizaje en educación primaria. Los resultados revelaron un efecto positivo significativo en múltiples aspectos del proceso educativo. En primer lugar, se observó un aumento notable en la motivación de los estudiantes, con un 85% reportando una mejora en su disposición para aprender al utilizar aplicaciones móviles en el aula. Esta mayor motivación puede atribuirse a la naturaleza interactiva y atractiva de las aplicaciones móviles, que facilitan la participación activa de los estudiantes en su propio aprendizaje. Además, se encontró que el rendimiento académico de los estudiantes mejoró en un promedio del 15% después de la implementación de tecnologías móviles en el aula, sugiriendo que estas herramientas pueden ser efectivas para reforzar los conceptos educativos y promover un aprendizaje más profundo y significativo. Esta mejora en el rendimiento es crucial para garantizar el éxito educativo de los estudiantes y prepararlos para los desafíos futuros. Por otro lado, se identificó una percepción positiva por parte de los padres, con un 60% reportando una visión favorable sobre el uso de tecnologías móviles en la educación de sus hijos. Esta aceptación por parte de los padres es fundamental para fomentar la colaboración entre la escuela y el hogar en el proceso educativo. En conjunto, estos hallazgos respaldan la relevancia y la eficacia de la integración de tecnologías móviles en la educación primaria, señalando la importancia de seguir investigando y desarrollando estrategias para maximizar sus beneficios y promover un aprendizaje inclusivo y equitativo para todos los estudiantes.
Kanban: Una metodología ágil para la gestión eficiente del flujo de trabajo en el desarrollo de software, una revisión sistemática
Authors: Castillo Anzules Marlon , Guaña Moya Edison Javier 
Published: May 2024

En la actualidad, la metodología Kanban ha cobrado relevancia en el desarrollo de software gracias a su enfoque ágil y su capacidad para optimizar la gestión del flujo de trabajo. Fundamentada en principios Lean, Kanban se materializa mediante tableros visuales que muestran el progreso del trabajo en etapas como "Backlog", "En progreso" y "Listo". Esta revisión sistemática empleó estudios de caso para analizar los beneficios, desafíos y prácticas asociados con la implementación de Kanban en el desarrollo de software ágil, extrayendo información sobre sus herramientas, beneficios y desafíos. Los beneficios identificados incluyen una mayor eficiencia y transparencia en el flujo de trabajo, fomento del trabajo en equipo y una mejor planificación y organización, aunque se identificaron desafíos relacionados con la coordinación del equipo y posibles cuellos de botella. Los resultados de los casos de estudio evidencian una mejora significativa en la eficiencia y productividad al implementar Kanban, destacando su adaptabilidad y flexibilidad en diversos contextos de desarrollo de software.
Pogranicze mazursko - kurpiowskie w powstaniu styczniowym 1863-1864
Authors: Kudrzycki Zbigniew 
Published: May 2024

Prusy Wschodnie w okresie powstania styczniowego stały się regionem przez, który zorganizowano transport broni kupowanej na zachodzie Europy do oddziałów powstańczych walczących na Północnym Mazowszu. Teren pogranicza mazursko – kurpiowskiego ze względu na lesistość i relatywnie małoliczne oddziały pruskiej i rosyjskiej straży granicznej predestynował do przerzutu broni przez granicę. W te działania zaangażowali się Mazurzy, Kurpie i Żydzi działający z pobudek patriotycznych, jak i z chęci zysku. Policja pruska prowadziła intensywne śledztwo doprowadzając do licznych aresztowań osób zajmujących się transportem broni na Kurpie. Zachowane dokumenty śledcze i sądowe pokazują osoby prowadzące tę działalność i skalę tego przedsięwzięcia.
Study of DNA Methylation in Offsprings of Individuals with Type 2 Diabetes Mellitus
Authors: Kaur Sukhraj , Kapahi Ruhi , Grover Inderpal Singh , Sharma Ritu , Sandhu Pashaura Singh 
Published: May 2024

Introduction: Epigenetic is study of changes in gene expression that occur by changing the DNA methylation and remodeling chromatin. It may also be affected by the environment. It is an important pathogenic mechanisms in complex multifactorial diseases such as type two diabetes. Recent genome-wide association studies have identified a number of genetic variants that explain some of the inter individual variation in diabetes susceptibility. Thus keeping in view, the role of epigenetic mechanisms particularly DNA methylation, the present study was conducted to find out DNA methylation (Whole DNA) in offsprings of individuals with type 2 Diabetes Mellitus.
Methods: For the present study, the families of one hundred Diabetic individuals were enrolled. All the off springs of diabetics above the age of 18 years were recruited for the present study. All the samples collected were analyzed for Fasting plasma glucose, Glycosylated Hemoglobin, Lipid profile complete and DNA methylation (5mcytosine).
Results: The study included 100 diabetic individuals and their off springs in the age range of 18-35 years. DNA methylation measured as 5mc% was significantly (p<0.001) more in IFG and Diabetic offsprings as compared to normal individuals both males and females.
Conclusions: Altered DNA Methylation in individuals of the age group 18-24 years indicates towards deranged metabolism in these individuals, leading to impaired fasting glucose and making them more prone to type 2 Diabetes Mellitus and its complications at a later age.
Drug Utilization Evaluation of Antidepressant Prescribing Practice in a Psychiatric Outpatient Hospital: A Prospective Cross-Sectional Study
Authors: Uppula Vaishnavi , Nitturi Tejasri , Padi Satyanarayana SV , Bandari Jagadeesh Babu , Puluru Manjula 
Published: May 2024

Background: One of the main causes of morbidity is psychiatric disorders, which are becoming a burden to public health. The therapeutic choices are influenced by several factors, including treatment paradigms, safety, and costs that determine outcomes.
Aim: We carried out the drug utilization evaluation (DUE) of antidepressants in patients visiting the psychiatry outpatient department.
Study Design: An observational, prospective, and cross-sectional study.
Place and Duration of Study: Department of Psychiatry, Jaya Krishna Hospital, Hanamkonda, TS, between September 2021 to April 2022.
Methodology: We included patients who visited the psychiatric outpatient hospital, were clinically diagnosed, and received any antidepressants for the long term. The relevant data collected from the information resources was systematically analyzed for DUE.
Results: Among 417 patients, the majority were in the age group of 31-40 (33.3%) years, and the most affected were female (57.3%), married (73.4%), and housewives (29.5%). Depression (37.6%) was the most commonly diagnosed psychiatric disorder. Of these prescriptions, 5.3% were monotherapy, the remaining was polytherapy (94.7%), and the majority of them had three drugs (36.2%). The average number of drugs per encounter was 3.4, drugs prescribed by generic names were 41.4%, injectable drugs prescribed were 2.6%, and drugs listed in the National List of Essential Medicines were 61.3%. Of all, 88.7% of prescriptions had at least one antidepressant, predominantly SSRIs, and fluoxetine (23.0%) was the most commonly prescribed. Benzodiazepines (59.7%) were the most frequently prescribed concomitant drug class and clonazepam (50.6%) was the most widely prescribed. Suicidal thoughts (5.8%) were the most commonly observed ADR.
Conclusion: The study observed a pattern of polytherapy, mainly antidepressants from the SSRIs, notably fluoxetine mostly prescribed, and suicidal thoughts were the frequent ADR. Drug use surveillance studies, rationalizing therapeutic choices, and proper patient counseling would improve therapeutic outcomes by minimizing side effects and ADRs.
Genome‐Wide Fitness and Genetic Interactions Determined by Tn‐seq, a High‐Throughput Massively Parallel Sequencing Method for Microorganisms
Authors: van Opijnen Tim , Camilli Andrew 
Published: November 2010

AbstractThe lagging annotation of bacterial genomes and the inherent genetic complexity of many phenotypes is hindering the discovery of new drug targets and the development of new antimicrobials and vaccines. Here we present the method Tn‐seq, with which it has become possible to quantitatively determine fitness for most genes in a microorganism and to screen for quantitative genetic interactions on a genome‐wide scale and in a high‐throughput fashion. Tn‐seq can thus direct studies in the annotation of genes and untangle complex phenotypes. The method is based on the construction of a saturated Mariner transposon insertion library. After library selection, changes in frequency of each insertion mutant are determined by sequencing of the flanking regions en masse. These changes are used to calculate each mutant's fitness. The method has been developed for the Gram‐positive bacterium Streptococcus pneumoniae, a causative agent of pneumonia and meningitis; however, due to the wide activity of the Mariner transposon, Tn‐seq can be applied to many different microbial species. Curr. Protoc. Microbiol. 19:1E.3.1‐1E.3.16. © 2010 by John Wiley & Sons, Inc.
Isolation of Streptomyces Species from Soil
Authors: Kharel Madan K. , Shepherd Micah D. , Nybo Stephen E. , Smith Michael L. , Bosserman Mary A. , Rohr Jürgen 
Published: November 2010

AbstractThis unit describes a general protocol for the isolation of Streptomyces species from soil and fresh water, using a procedure for the selective growth of Streptomyces species. Preparation of the necessary growth medium, recognition of the morphology of the bacteria, and safety considerations are also covered. Curr. Protoc. Microbiol. 19:10E.4.1‐10E.4.5. © 2010 by John Wiley & Sons, Inc.
Photodegradation of thermodegraded polypropylene/high‐impact polystyrene blends: Mechanical properties
Authors: Fernandes L. L. , Freitas C. A. , Demarquette N. R. , Fechine G.J. M. 
Published: November 2010

AbstractThe influence of the addition of high‐impact polystyrene (HIPS) on polypropylene (PP) photodegradation was studied with blends obtained by extrusion with and without styrene–butadiene–styrene (SBS) copolymer (10 wt % with respect to the dispersed phase). The concentrations of HIPS ranged from 10 to 30 wt %. The blends and pure materials were exposed for periods of up to 15 weeks of UV irradiation; their mechanical properties (tensile and impact), fracture surface, and melt flow indices were monitored. After 3 weeks of UV exposure, all of the materials presented mechanical properties of the same order of magnitude. However, for times of exposure greater than 3 weeks, an increasing concentration of HIPS resulted in a better photostability of PP. These results were explained in light of morphological observations. This increase of photostability was even greater when SBS was added to the blends. It was more difficult to measure the melt flow index of the binary PP/HIPS blends than that of PP for low concentrations of HIPS; this was most likely due to energy transfer between the blend domains during photodegradation. This phenomenon was not observed for the ternary blends. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Binding His‐tagged Proteins to NTA Stripes Assembled in 2D DNA Scaffold
Authors: Huang Wenyi , Chao Jie , Yan Qin , Xiao Shoujun 
Published: November 2010

AbstractHistidine‐tagged proteins were bound onto nitrilotriacetic acid (NTA) stripes on a 2‐D DNA scaffold which involved a ssDNA‐NTA conjugate prepared by click chemistry.
Influence of Montmorillonite's Concentration on the Thixotropy of Hydrotalcite‐like Compounds/Montmorillonite Suspensions
Authors: Jia Chunxiao , Li Shuping , Zong Hui 
Published: November 2010

AbstractIn this paper, we found that the change of sodium montmorillonite's (MT) concentration in the magnesium‐aluminum‐ferrum hydrotalcite‐like compounds (Mg‐Al‐Fe‐HTlc)/MT suspensions would greatly influence the thixotropic type of the suspensions. Specifically, the increase in the MT's concentration increases the viscosities (η) of the HTlc/MT suspensions with the same R value (the mass ratio of HTlc to MT was signed as R, e.g., R=mHTlc/mMT), meaning that the structure strength of the HTlc/MT suspensions increases. With the variation of MT's concentration, the thixotropic type of the HTlc/MT suspensions changed accordingly, and the mechanism has been discussed in this paper.
An Effective Method for Bulk Obtaining Graphene Oxide Solids
Authors: Wang Jingchao , Wang Xianbao , Wan Li , Yang Yingkui , Wang Shimin 
Published: November 2010

AbstractWe report an effective method for bulk obtaining exfoliated graphene oxide (GO) solids from their aqueous solutions, which were prepared from nature graphite by an oxidation method. Tyndall effect proved that GO solution has a colloidal nature. Different flocculants were used to coagulate GO colloidal, and it was found that NaOH had the most obvious coagulation effect to GO. Transmission electron microscopy, X‐ray diffraction and atomic force microscopy analysis demonstrated that there were a large number of complete few‐layer GO sheets with thickness of about 0.8 nm, and the surfaces were very smooth, almost free of impurities. Liquid state 13C NMR and Fourier transformation infrared spectra showed the presence of abundant benzene carboxylic, hydroxyl and epoxide groups in the basal planes of GO. The graphene materials reduced from GO solids had good electrical conductivity. Our work explored a simple and effective route to extract GO from their solution, which is the most important to GO and graphene researches and applications.
Experimental study of the retention properties of a cyclo olefin polymer pillar array column in reversed‐phase mode
Authors: Illa Xavi , De Malsche Wim , Gardeniers Han , Desmet Gert , Romano‐Rodríguez Albert 
Published: November 2010

AbstractExperimental measurements to study the retention capacity and band broadening under retentive conditions using micromachined non‐porous pillar array columns fabricated in cyclo olefin polymer are presented. In particular, three columns with different depths but with the same pillar structure have been fabricated via hot embossing and pressure‐assisted thermal bonding. Separations of a mixture of four coumarins using varying mobile phase compositions have been monitored to study the relation between the retention factor and the ratio of organic solvent in the aqueous mobile phase. Moreover, the linear relation between the retention and the surface/volume ratio predicted in theory has been observed, achieving retention factors up to k=2.5. Under the same retentive conditions, minimal reduced plate height values of hmin=0.4 have been obtained at retention factors of k=1.2. These experimental results are compared with the case of non‐porous and porous silicon pillars. Similar results for the plate heights are achieved while retention factors are higher than the non‐porous silicon column and considerably smaller than the porous pillar column, given the non‐porous nature of the used cyclo olefin polymer. The feasibility of using this polymer column as an alternative to the pillar array silicon columns is corroborated.
Separation and detection of polar cuticular components from Oriental tobacco leaf by integration of normal‐phase liquid chromatography fractionation with reversed‐phase liquid chromatography‐mass spectrometry
Authors: Ding Li , Xie Fuwei , Xu Guowang , Liu Kejian , Wang Sheng , Xie Jianping 
Published: November 2010

AbstractIntegration of normal‐phase LC (NPLC) fractionation with RPLC‐ESI/MS was established to detect the polar fractions of cuticular components from Oriental tobacco leaf. NPLC was selected for the fractionation of polar components of cuticular leaf extract, after being concentrated with rotary evaporator, each of the enriched fractions was further analyzed by RPLC‐ESI/MS. In total, 83 compounds were finally detected including 45 cembranoids, 15 labdanoids, 20 sucrose esters, and 3 glucose esters (or fructose esters). Three cembranoids and seven labdanoids possibly are new diterpenoids. Glucose esters (or fructose esters) are also reported in Nicotiana tobacco for the first time.
Acute motor axonal neuropathy in association with Sjögren syndrome
Authors: Awad Amer , Mathew Sani , Katirji Bashar 
Published: November 2010

AbstractSjögren syndrome (SS) has been known to manifest with neurological complications, most frequently of the peripheral nervous system, and often in advance of xerostomia and xerophthalmia. There has been one case report of a patient with SS presenting with acute motor neuropathy similar to Guillain–Barré syndrome (GBS). We report the case of a patient who developed rapidly fulminant acute motor axonal neuropathy (AMAN) with positive anti‐GM1 antibody at high titers in association with serological and pathological evidence of SS without xerostomia or xerophthalmia. Muscle Nerve 42: 828–832, 2010
Kinetic analysis of surface‐initiated SET‐LRP of poly(N‐isopropylacrylamide)
Authors: Turan Eylem , Caykara Tuncer 
Published: November 2010

AbstractThe single‐electron transfer living radical polymerization (SET‐LRP) of N‐isopropylacrylamide (NIPAM) from silicon wafer modified with an initiator layer composed of 2‐bromopropionyl bromide (2‐BPB) fragments is described. The amount of Cu(0) generated in situ by the disproportination of Cu(I) to Cu(0) and Cu(II) in the presence of 2,2′‐bipyridine (2,2′‐bpy) ligand and N,N‐dimethylformamide (DMF) solvent at 90 °C is dependent on the ratio of [CuBr]/[CuBr2]. By proper selection of the [CuBr]/[CuBr2] ratio, well‐controlled SET‐LRP polymerization of NIPAM was observed such that the thickness of the layer consisting of chains grown from the surface increased linearly with the molecular weight of chains polymerized in solution in identical. In addition, the calculation of grafting parameters, including surface coverage, σ (mg/m2); grafting density, Σ (chain/nm2); and average distance between grafting sites, D (nm), from the number‐average molecular weight, Mn (g/mol), and ellipsometric thickness, h (nm), values indicated the synthesis of densely grafted poly(NIPAM) films and allowed us to predict a “brush‐like” conformation. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010
Blue‐light‐emitting polyfluorene functionalized with triphenylamine and cyanophenylfluorene bipolar side chains
Authors: Lin Ying , Ye Teng‐Ling , Chen Yu , Ma Dong‐Ge , Chen Zhi‐Kuan , Dai Yan‐Feng , Li Yong‐Xi 
Published: November 2010

AbstractA new bipolar conjugated polyfluorene copolymer with triphenylamine and cyanophenylfluorene as side chains, poly{[9,9‐di(triphenylamine)fluorene]‐[9,9‐dihexyl‐fluorene]‐[2,7‐bis(4′‐cyanophenyl)‐9,9′‐spirobifluorene]} (PTHCF), was synthesized for studying the polymer backbone emission. Its absolute weight‐average molecular weight was determined as 4.85 × 104 by using gel permeation chromatography with a multiangle light scattering detector. In contrast to the electronic absorption spectrum in dilute solution, the absorbance of PTHCF in thin film was slightly blue shifted. By comparison of the solution and thin‐film photoluminescence (PL) spectra, a red shift of Δλ = 8–9 nm was observed in the thin‐film PL spectrum. The HOMO and LUMO energy levels of the resulting polymer were electrochemically estimated as −5.68 and −2.80 eV, respectively. Under the electric‐field intensity of 4.8 × 105 V cm−1, the obtained hole and electron mobilities were 2.41 × 10−4 and 1.40 × 10−4 cm2 V−1 s−1, respectively. An electroluminescence device with configuration of ITO/PEDOT:PSS/PTHCF70%+PBD30%/CsF/Ca/Al exhibited a deep‐blue emission as a result of excitons formed by the charges migrating along the full‐fluorene main chain. The incorporation of the bipolar side chains into the polymer structure prevented the intermolecular interaction of the fluorene moieties, balance charge injection/transport, and thereby improve the polymer backbone emission. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010
Biomarkers as disease definition: Mantle cell lymphoma as an example
Authors: van Krieken Johan H. J. M. , Jansen Corine , Hebeda Konnie M. , Groenen Patricia J. T. A. 
Published: November 2010

AbstractThe introduction in pathology practice of a new biomarker that is contributing to define a disease requires a series of investigations. Now that new biomarkers are being discovered continuously it is important to learn from successful examples of markers that are presently widely used. In this historical account the steps are described that have led to the use of immunohistochemical staining of tissue samples with an antibody against cyclinD1 to diagnose mantle cell lymphoma. Furthermore, a short outlook is given on the introduction of proteomics as a tool in the diagnosis of lymphoma and the potential route to be taken for introducing this technology into clinical practice.
Toward the modeling of the NO2(2A″) manifold
Authors: Mota V. C. , Caridade P. J. S. B. , Varandas A. J. C. 
Published: November 2010

AbstractGlobal diabatization angles are obtained to construct a 3 × 3 diabatic potential matrix for the 2A″ states of NO2. Over 12,500 energies have been calculated to map ab initio, the configuration space of (at least) the first 3 adiabatic sheets. With the level of theory used, such angles could be modeled such as to ensure a proper description of all involved crossing seams as well as the merging of the diabats into the adiabats at the asymptotic limits. This result provides an extension to the 3‐state case of the method proposed earlier (Mota and Varandas, J Phys Chem A 2008, 112, 3768), and illustrates the essential steps toward the modeling of the NO2(2A″) manifold via double many‐body expansion theory. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2011