bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agreement among HLA antibody detection assays is higher in ever‐pregnant donors and improved using a consensus cutoff
Authors: Carrick Danielle M. , Johnson Bryce , Kleinman Steven H. , Vorhaben Robert , Chance Suzette C. , Lee Jar‐How , Roback John D. , Pandey Suchitra , Sun Yu , Busch Michael P. , Norris Philip J. ,   for the NHLBI Retrovirus Epidemiology Donor Study‐II (REDS‐II)
Published: November 2010

BACKGROUND: HLA antibodies might contribute to the pathogenesis of transfusion‐related acute lung injury (TRALI). HLA antibody detection methods include ELISA, flow cytometry, and multiplex bead‐based assays, as well as the older lymphocytotoxicity assay, and it is not obvious how to compare results across platforms.STUDY DESIGN AND METHODS: Five hundred twenty‐five serum samples were selected from 7841 donors in the Leukocyte Antibody Prevalence Study (LAPS) repository based on risk for the development of HLA antibodies, using the number of pregnancies as the risk factor. Subjects included 81 males and females with 0 (n = 187), 1 (n = 67), or 2+ pregnancies (n = 190). Replicate frozen serum aliquots were sent blinded to four different HLA antibody assay manufacturers for detection using five different assays.RESULTS: The flow cytometry and multiplex bead based‐assays typically resulted in a larger proportion of HLA antibody positive samples compared with ELISA based assays. Latent variable analysis was used to derive a new set of consensus cutoffs, which yielded similar sensitivities across test platforms and increased concordance amongst assays. Assay agreement was higher in ever pregnant females than in males and never‐pregnant females.CONCLUSIONS: Different assays resulted in varied positivity rates when the manufacturer's suggested cutoffs were used, demonstrating that care needs to be taken when comparing clinical outcomes data generated using different HLA antibody assays and testing platforms. The method used here, involving latent variable analysis, presents one possible approach to calculating comparable cutoffs that result in broad agreement across assays with respect to positivity designation.
Arteriovenous fistula: end‐to‐end or end‐to side anastomosis?
Authors: STANZIALE Rodolfo , LODI Massimo , D'ANDREA Enrico , Sammartino Fulvio , DI LUZIO Virgilio 
Published: November 2010

AbstractThe purpose of the present study was to compare the end‐to‐end (ETEa) with the end‐to‐side (ETSa) anastomosis in patients starting hemodialysis by means of radio‐cephalic artero‐venous fistulae (AVF). In our experience, we compared the results, as early failure (EF), late thrombosis (LT), stenosis, steal syndrome, and primary patency (PP), in 2 groups of hemodialysis incident patients that had been placed an AVF by means of ETEa or ETSa. The observation period lasted 24 months for each of the 2 types of AVF, starting from October 2005 to September 2007 for ETEa and from October 2007 to September 2009 for ETSa. One hundred forty patients were included in the present study. We have consecutively performed 99 AVF interventions at the wrist or at the third distal of the forearm, in 70 patients by means of ETEa and 82 AVF interventions in the same anatomical places in 70 patients by means of ETSa. The patients with ETEa had a mean age of 64.4 ± 14.6 years, males were 65.8% and the age dialysis at the end of observation was 10.4 ± 5.7 months. Those with ETSa had a mean age of 65.9 ± 15.5 years and the males were 62.9%, the age dialysis at the end of observation was 9.2 ± 5.5 months. The surgical team was composed by the same nephrologists. The statistical study was performed by means of the χ chi‐square and Fisher's exact test. We have observed more late thrombosis (10% vs. 4.1%) and stenosis (21.4% vs. 2.7%) in ETEa than in ETSa. The number of early thrombosis was similar in the 2 types of anastomosis. The primary patency 1‐year rate was better though not significantly in the ETS (80% vs. 85.7%) In our experience the ETSa provides, overall better results, both regarding the complications and primary survival than ETEa. For the benefits that seem to come from it, we believe, that a broad ETSa in the distal native AVF is preferable to the ETEa.
Lakeshore residential development and growth of largemouth bass (Micropterus salmoides): a cross‐lakes comparison
Authors: Gaeta J. W. , Guarascio M. J. , Sass G. G. , Carpenter S. R. 
Published: November 2010

Gaeta JW, Guarascio MJ, Sass GG, Carpenter SR. Lakeshore residential development and growth of largemouth bass (Micropterus salmoides): a cross‐lakes comparison. Ecology of Freshwater Fish 2011: 20: 92–101. © 2010 John Wiley & Sons A/SAbstract –  Lakeshore residential development is associated with changes in littoral habitat, riparian habitat, and ecosystem function with potential impacts ramifying through aquatic food webs. Effects of these changes on economically important game fishes may vary with fish size. We investigated largemouth bass (Micropterus salmoides) size‐specific growth rates across 16 lakes spanning the range of lakeshore residential development in Wisconsin’s Northern Highland Lake District using a longitudinal multilevel model. Growth rates of small fish had a strong positive relationship with lakeshore residential development. The strength of the relationship decreased with length and became increasingly negative for fish longer than 210 mm. This pattern may be driven by a release from density‐dependent growth, shifts in available prey sources, reduced macrophyte cover, or angling‐induced selection pressures. Regardless of the mechanism, our results indicate, relative to undeveloped lakes, largemouth bass in highly developed lakes take 1.5 growing seasons longer to enter the fishery (356 mm).
Efron's Bootstrap
Authors: Boos Dennis , Stefanski Leonard 
Published: November 2010

AbstractThe bootstrap was introduced by Brad Efron in the Late 1970s. It is a computer-intensive method for approximating the sampling distribution of any statistic derived from a random sample. Here Dennis Boos and Leonard Stefanski give simple examples to show how the bootstrap is used and help to explain its enormous success as a tool of statistical inference.
Southern Nevada assisted living residents’ perception of their oral health status and access to dental care
Authors: Dounis Georgia , Ditmyer Marcia M. , McCants Robert , Lee Yoonah , Mobley Connie 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00434.xSouthern Nevada assisted living residents’ perception of their oral health status and access to dental careObjective:  Oral health is an integral component of general health, and quality of life. The purpose of this study was to determine the perceptions of oral health status and acces\s to dental care by Southern Nevada Assisted Living Facilities Residents.Methods:  A cross‐sectional questionnaire study design was used to survey residents between 34 and 99 years old residing in Assisted Living Facilities. Seventy respondents (42 males and 28 females) completed a survey that included personal oral hygiene, access to care, and demographic information. Data analyses included descriptive statistics and chi‐square.Results:  Mean age was 75.78 years, and the majority had a college education (n = 41). Four currently smoked cigarettes. Twenty‐nine (males = 14; females = 15) reported having dental insurance. Eleven respondents had seen a dentist twice a year, while 33 reported a visit less than 6 months. Forty‐one reported the facility did not provide oral health care with majority (n = 64) indicating that accessing oral health care was difficult. Self‐rated response to oral hygiene, a majority (n = 64) reported their oral hygiene as fair and five reported their oral hygiene as poor.Conclusions:  Assisted living residents in Southern Nevada reported difficulty accessing dental services within and outside of the facility. Oral care models to address this unique population should be explored.
Denture disinfection by microwave energy: influence of Candida albicans biofilm
Authors: Senna Plínio Mendes , da Silva Wander José , Del Bel Cury Altair Antoninha 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00439.xDenture disinfection by microwave energy: influence of Candida albicans biofilmObjective:  This study evaluated the influence of the area of Candida albicans biofilm on denture disinfection by microwave energy.Materials and methods:  Candida albicans biofilm was allowed to form for 72 h on resin discs, and three small coverage or seven large coverage discs were placed onto the palatal surface of sterile maxillary dentures. Each denture was immersed in 200 ml distilled water and individually irradiated at a power of 450, 630 or 900 W for different time intervals (1, 2 or 3 min) (n = 6). The effectiveness of disinfection was evaluated by counting the residual cells. The data were analysed by anova and Tukey’s HSD test (α = 0.05). Pearson’s correlation test was performed to determine the correlation between effectiveness of sterilisation and temperature.Results:  Dentures with a larger area of biofilm demanded a longer irradiation exposure to achieve disinfection (p < 0.001), irrespective of power setting, and in this time no yeast growth was detected. Dentures with small areas of biofilm were disinfected after 1 min at 900 W and 2 min at 450 or 630 W. A positive correlation was found between water temperature and effectiveness of disinfection (r = 0.6170; p < 0.001).Conclusion:  The C. albicans biofilm area influenced disinfection by microwave energy; therefore dentures with larger biofilm areas required longer irradiation exposure to be disinfected.
Loss of natural dentition: multi‐level effects among a geriatric population
Authors: Divaris Kimon , Ntounis Athanasios , Marinis Aristotelis , Polyzois Gregory , Polychronopoulou Argy 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00440.xLoss of natural dentition: multi‐level effects among a geriatric populationObjective:  To quantify the impact of edentulousness on residual ridge volume, denture stomatitis (DS), as well as oral health behaviours among geriatric denture‐wearers.Background:  Residual ridge resorption (RRR) is the primary intraoral complication of complete edentulism, but individual variation among geriatric patients has been observed.Materials and methods:  Data collection relied upon a 10‐year retrospective chart review of all complete denture‐wearing geriatric patients presenting at the Removable Prosthodontics Clinic, Dental School of Athens, between 1993 and 2002. Analyses relied on descriptive, bivariate, and multivariate methods based on ordinal logistic regression.Results:  A total of 873 records of geriatric patients (age mean = 72; median = 70; range = 65–95) comprised our analytical sample. Subjects’ mean (SD) time since edentulation was 7.7 (10.2) years. Eleven percent were diagnosed with temporomandibular disorder (TMD). While 28% of patients reported cleaning their dentures at least daily, 6% presented with denture stomatitis (DS). Each added year of edentulism increased the odds of mandibular RRR: OR (95% CI) = 1.05 (1.03, 1.07). Nightly denture wear was the strongest risk factor for DS. Finally, independent of age and sex, each year of being edentulous increased the odds of presenting with TMD: OR (95% CI) = 1.03 (1.01, 1.05).Conclusion:  Time since edentulation was strongly associated with mandibular but not maxillary RRR, as well as TMD development.
Analysis of socio‐demographic and systemic health factors and the normative conditions of oral health care in a population of the Brazilian elderly
Authors: Mendes Danilo Cangussu , de Oliveira Poswar Fabiano , de Oliveira Marcus Vinícius Macedo , Haikal Desirée Sant′Ana , da Silveira Marise Fagundes , de Barros Lima Martins Andréa Maria Eleutério , De Paula Alfredo Maurício Batista 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00446.x

Analysis of socio‐demographic and systemic health factors and the normative conditions of oral health care in a population of the Brazilian elderlyObjective:  To investigate the association of socio‐demographic and systemic health factors according to the normative conditions of oral health care (dental caries, edentulism, periodontal disease and oral mucosal lesion) in elderly individuals.Material and methods:  A cross‐sectional study was carried out in a group of elderly with access to community health care (n = 200). The normative conditions of oral health were then investigated according to the WHO and the SB Brazil criteria. Bivariate analyses were evaluated by the chi‐square test and Fisher’s exact test. An estimation of prevalence for the covariates was performed using Poisson’s regression models.Results:  The prevalence of edentulism and oral mucosal lesions was detected in 58% and 21.5% of elderly patients, respectively. In the dentate subjects, the prevalence of dental caries and periodontal disease was 51.2% and 20.8%, respectively. Older men and individuals from lower‐income groups exhibited a higher prevalence of dental caries. Elderly women, illiterate individuals, and individuals over the age of 65 years exhibited a higher prevalence of edentulism. Elderly 60–64 years old and those who are employed had a significant association with periodontal disease.Conclusion:  Socio‐demographic factors were associated with some notable oral diseases in the elderly.
Effect of thermocycling on hardness, absorption, solubility and colour change of soft liners
Authors: Mancuso Daniela Nardi , Goiato Marcelo Coelho , Zuccolotti Bruna Carolina Rossatti , Moreno Amália , dos Santos Daniela Micheline , Pesqueira Aldiéris Alves 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00447.x

Effect of thermocycling on hardness, absorption, solubility and colour change of soft linersObjective:  The effect of artificial ageing on the hardness, absorption, solubility, and colour of soft denture liners was investigated.Materials and methods:  Liner materials based on acrylic resin (Trusoft) or silicone (Dentusil, Ufi Gel P, and Ufi Gel SC) were tested before and after 2000 thermal cycles. A total of 20 specimens of each material were tested. Half of the specimens were used for hardness and colour evaluation, and the remainder for absorption and solubility tests. The hardness evaluation was carried out using a Shore A durometer, while absorption and solubility tests were performed by storing samples in a desiccator and weighing daily until reaching constant mass (W1). After thermocycling, the samples were again weighed (W2) and dried (W3). Colour was measured using a spectrophotometer. Statistical analysis was performed using GraphPad InStat at the p < 0.05 level.Results:  Thermocycling significantly affected the hardness of the specimens. The Trusoft material exhibited the highest absorption (1.48 ± 0.48), solubility (1.26 ± 0.28), and colour change (3.92 ± 0.33), significantly different from the other materials. There were no significant differences among the silicones in terms of absorption, solubility, and colour change, except for the colour of Dentusil, which changed (0.83 ± 0.11).Conclusion:  It can be concluded that silicone liners performed significantly better compared to acrylic resin.
Investigation of oral opportunistic pathogens in independent living elderly Japanese
Authors: Ogawa Taiji , Ikebe Kazunori , Enoki Kaori , Murai Shunsuke , Maeda Yoshinobu 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00449.x

Investigation of oral opportunistic pathogens in independent living elderly JapaneseObjective:  Pneumonia is reported to be associated with high morbidity in elderly and compromised individuals, with poor oral health demonstrated to be a significant risk factor for pneumonia. Several opportunistic pathogens, such as Streptococcus pneumoniae, Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus, have been detected in patients with pneumonia. We investigated the prevalence of opportunistic pathogens in the oral cavity of healthy independent living Japanese elderly subjects and analysed factors related to harbouring those pathogens.Materials and methods:  We studied 265 subjects, each of whom received a dental examination, during which specimens were collected with a tongue swab and examined for the presence of 10 oral opportunistic pathogens using single or multiple selective media. Furthermore, the presence of occult blood in saliva was examined using test paper strips.Results:  Oral opportunistic pathogens were detected in 13.6% of the subjects. Those positive for occult blood in saliva had a significantly higher rate of harbouring the pathogens (p < 0.05). In addition, age was a significant factor for the presence of pathogenic microbes in the oral cavity (p = 0.033).Conclusion:  Positive findings of occult blood in saliva and older age are suggested to be significant factors for harbouring opportunistic pathogens in the oral cavity.
Oral malignant melanoma – an unusual presentation
Authors: Thomas Priya Sara , Subhas Babu Gogineni , Anusha Rangare Laxman , Shetty Shishir 
Published: November 2010

doi: 10.1111/j.1741‐2358.2010.00450.x

Oral malignant melanoma – an unusual presentationMalignant melanoma is the least common but most deadly of all primary skin cancers. Oral malignant melanoma is a rare aggressive neoplasm usually seen in middle aged persons. This malignancy is more frequently seen on the hard palate and gingiva. Oral melanomas are associated with very poor prognosis because of the tendency to metastasise or invade tissues locally more readily than other malignant tumours of the oral cavity especially in the case of a geriatric patient. The surgical approach, combined with the chemotherapy, is the first choice treatment. This report highlights a case report of 71‐year‐old female patient diagnosed and treated surgically for an oral malignant melanoma of the pedunculated variety affecting the hard palate and gingiva with review of literature.
WBC27, an Adenosine Tri‐phosphate‐binding Cassette Protein, Controls Pollen Wall Formation and Patterning in Arabidopsis
Authors: Dou Xiao‐Ying , Yang Ke‐Zhen , Zhang Yi , Wang Wei , Liu Xiao‐Lei , Chen Li‐Qun , Zhang Xue‐Qin , Ye De 
Published: November 2010

Abstract In flowering plants, the exine components are derived from tapetum. Despite its importance to sexual plant reproduction, little is known about the translocation of exine materials from tapetum to developing microspores. Here we report functional characterization of the arabidopsis WBC27 gene. WBC27 encodes an adenosine tri‐phosphate binding cassette (ABC) transporter and is expressed preferentially in tapetum. Mutation of WBC27 disrupted the exine formation. The wbc27 mutant microspores began to degenerate once released from tetrads and most of the microspores collapsed at the uninucleate stage. Only a small number of wbc27‐1 microspores could develop into tricellular pollen grains. These survival pollen grains lacked exine and germinated in the anther before anthesis. All of these results suggest that the ABC transporter, WBC27 plays important roles in the formation of arabidopsis exine, possibly by translocation of lipidic precursors of sporopollenin from tapetum to developing microspores.
Core body temperature and the thermoneutral zone: a longitudinal study of normal human pregnancy
Authors: Hartgill T. W. , Bergersen T. K. , Pirhonen J. 
Published: November 2010

AbstractAim:  Using a longitudinal study design, we investigated changes in maternal core temperature and ambient temperatures before and after a localized cooling procedure to the right hand.Methods:  Fifteen pregnant women participated. The experiments were sequentially performed for 21 month periods on each subject: from the 8th week of gestation to 1 year after delivery on seven separate occasions (gestational weeks 8, 16, 26, 36 and 12, 24, 52 weeks post‐partum). The experiments were conducted in a climactic chamber, allowing ambient temperature adjustment to each subjects’ thermoneutral zone determined using Doppler ultrasound of the digital artery.Results:  Maternal core temperature decreased from 37.1 °C (week 8) towards term, reaching a nadir (36.4 °C) at 12 weeks post‐partum (P < 0.001). The ambient temperature required to reach the thermoneutral zone changed significantly from 26.5 °C (week 8) falling to its lowest point: 23.0 °C (week 36) (P < 0.001), then stabilized from 24 weeks post‐partum.Conclusion:  Maternal core temperature is highest in the first trimester but falls during pregnancy to a nadir 3 months post‐partum. The ambient temperature required to reach the thermoneutral zone was 4 °C lower at 36 weeks of gestation compared with early pregnancy and late post‐partum. Human temperature regulation is altered in pregnancy and for at least 3 months post‐partum.
Effects of optimum doses of nitrogen, phosphorus, potassium and calcium on silkworm, Bombyx mori L., growth and yield
Authors: KHAN Muhammad A. , AKRAM Waseem , ASHFAQ Muhammad , KHAN Hafiz A. A. , KIM Yeon K. , LEE Jong‐Jin 
Published: November 2010

AbstractSilkworm rearing has been an income source for small‐holding farmers in Pakistan. Over the years efforts have been made to improve silkworm quality and quantity and thus develop better prospects for increasing yield and income. Mulberry leaves Morus alba L. in a series of experiments have been supplemented with various nutrients in different doses and combinations. Relative success has been achieved in this context. In our present experiments on silkworm Bombyx mori L., we fed the larvae on mulberry leaves supplemented with different doses of N (0.2%), P (0.1%), K (0.3%) and Ca (0.1%) at 26 ± 3°C with 65 ± 5% relative humidity. The results showed better outputs in terms of food consumption (72.55 g/10 larvae), coefficient of utilization (76.45%), body weight (70.07 g/10 larvae) and body length (8.56 cm/larvae) than where simple mulberry leaves were offered. Our net gains with these production parameters have been in terms of heavier cocoons with and without pupa (2.25 and 0.69 g/cocoon), respectively.
Distribution of Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) in tomato fields and its relationship to weather factors
Authors: WAKIL Waqas , GHAZANFAR M. Usman , KWON Yong Jung , QAYYUM Mirza A. , NASIR Fozia 
Published: November 2010

AbstractA survey was conducted in tomato fields at different localities to assess the distribution of tomato fruitworm Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) in Punjab Province, Pakistan. The effect of weather factors on its population was also investigated. Eleven tomato‐growing districts were selected and data for larval population and fruit infestation were recorded. The maximum larval population (5.2 larvae/plant) of H. armigera was recorded in Bahawalpur district with 32.6% fruit infestation. However, the minimum larval population (1.4 larvae/plant) inflicted 14.7% fruit infestation in Rawalpindi district. The temperature was positively correlated while relative humidity showed negative interaction with the larval population and fruit infestation.