bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual‐Site Biomacromolecule Doped Poly(3, 4‐Ethylenedioxythiophene) for Bosting Both Anticoagulant and Electrochemical Performances
Authors: Wang Xiangya , Niu Jianzhou , Hadi Mohammed Kamal , Guo Dongli , Zhang Yuxia , Yu Meimei , Zhou Qi , Ran Fen 
Published: May 2024

AbstractPoly(3, 4‐ethylenedioxythiophene) (PEDOT) as a new generation of intelligent conductive polymers, is attracting much attention in the field of tissue engineering. However, its water dispersibility, conductivity, and biocompatibility are incompatible, which limit its further development. In this work, biocompatible electrode material of PEDOT doped with sodium sulfonated alginate (SS) which contains two functional groups of sulfonic acid and carboxylic acid per repeat unit of the macromolecule. The as dual‐site doping strategy simultaneously boosts anticoagulant and electrochemical performances, for example, good hydrophilicity (water contact angle of 59.40°), well dispersibility (dispersion solution unstratified in 30 days), high conductivity (4.45 S m−1), and enhanced anticoagulant property (extended activated partial thrombin time value of 59.0 s), forming an adjustable PEDOT: biomacromolecule interface; this fills the technical gap of implantable bioelectronics in terms of coagulation and thrombosis risk. At the same time, the assembled all‐in‐one supercapacitor with anticoagulant properties is prepared by PEDOT: sodium sulfonated alginate as electrode material and sodium alginate hydrogel as electrolyte layer. The dual‐site doping strategy provides a new opinion for the design and optimization of functional conductive polymers and its applications in implantable energy storage fields.
Acoustic Metagrating Holograms
Authors: Zou Hong‐Yu , Ge Yong , Zhao Ke‐Qi , Lu Yu‐Jing , Si Qiao‐Rui , Yuan Shou‐Qi , Chen Hongsheng , Sun Hong‐Xiang , Yang Yihao , Zhang Baile 
Published: May 2024

AbstractMetasurface holograms represent a common category of metasurface devices that utilize in‐plane phase gradients to shape wavefronts, forming holographic images through the application of the generalized Snell's law (GSL). While conventional metasurfaces focus solely on phase gradients, metagratings, which incorporate higher‐order wave diffraction, further expand the GSL's generality. Recent advances in certain acoustic metagratings demonstrate an updated GSL extension capable of reversing anomalous transmission and reflection, whose reversal is characterized by the parity of the number of wave propagation trips through the metagrating. However, the current extension of GSL remains limited to 1D metagratings, unable to access 2D holographic images in 3D spaces. Here, the GSL extension to 2D metagratings for manipulating waves within 3D spaces is investigated. Through this analysis, a series of acoustic metagrating holograms is experimentally demonstrated. These holographic images exhibit the unique ability to switch between transmission and reflection types independently. This study introduces an additional dimension to modern holography design and metasurface wavefront manipulation.
Thermal Runaway Mechanism in Ni‐Rich Cathode Full Cells of Lithium‐Ion Batteries: The Role of Multidirectional Crosstalk
Authors: Jo Sugeun , Seo Sungjae , Kang Song Kyu , Na Ikcheon , Kunze Sebastian , Song Munsoo , Hwang San , Woo Sung Pil , Kim SoHee , Kim Won Bae , Lim Jongwoo 
Published: May 2024

AbstractCrosstalk, the exchange of chemical species between battery electrodes, significantly accelerates thermal runaway (TR) of lithium‐ion batteries. To date, the understanding of their main mechanisms has centered on single‐directional crosstalk of oxygen (O2) gas from the cathode to the anode, underestimating the exothermic reactions during TR. However, the role of multidirectional crosstalk in steering additional exothermic reactions is yet to be elucidated due to the difficulties of correlative in situ analyses of full cells. Herein, the way in which such crosstalk triggers self‐amplifying feedback is elucidated that dramatically exacerbates TR within enclosed full cells, by employing synchrotron‐based high‐temperature X‐ray diffraction, mass spectrometry, and calorimetry. These findings reveal that ethylene (C2H4) gas generated at the anode promotes O2 evolution at the cathode. This O2 then returns to the anode, further promoting additional C2H4 formation and creating a self‐amplifying loop, thereby intensifying TR. Furthermore, CO2, traditionally viewed as an extinguishing gas, engages in the crosstalk by interacting with lithium at the anode to form Li2CO3, thereby accelerating TR beyond prior expectations. These insights have led to develop an anode coating that impedes the formation of C2H4 and O2, to effectively mitigate TR.
Multicolor Inks of Black Phosphorus for Midwave‐Infrared Optoelectronics
Authors: Kim Jae Ik , Higashitarumizu Naoki , Wang Shu , Yalisove Reed , Scott Mary C. , Song Seung Yong , Javey Ali 
Published: May 2024

AbstractBlack phosphorus (bP) based ink with a bulk bandgap of 0.33 eV (λ = 3.7 µm) has recently been shown to be promising for large‐area, high performance mid‐wave infrared (MWIR) optoelectronics. However, the development of multicolor bP inks expanding across the MWIR wavelength range has been challenging. Here a multicolor ink process based on bP with spectral emission tuned from 0.28 eV (λ = 4.4 µm) to 0.8 eV (λ = 1.5 µm) is demonstrated. Specifically, through the reduction of bP particle size distribution (i.e., lateral dimension and thickness), the optical bandgap systematically blueshifts, reaching up to 0.8 eV. Conversely, alloying bP with arsenic (bP1−xAsx) induces a redshift in the bandgap to 0.28 eV. The ink processed films are passivated with an infrared‐transparent epoxy for stable infrared emission in ambient air. Utilizing these multicolor bP‐based inks as an infrared light source, a gas sensing system is demonstrated that selectively detects gases, such as CO2 and CH4 whose absorption band varies around 4.3 and 3.3 µm, respectively. The presented ink formulation sets the stage for the advancement of multiplex MWIR optoelectronics, including spectrometers and spectral imaging using a low‐cost material processing platform.
Achieving Exceptional Volumetric Desalination Capacity Using Compact MoS2 Nanolaminates
Authors: Ying Ting , Xiong Yu , Peng Huarong , Yang Ruijie , Mei Liang , Zhang Zhen , Zheng Weikang , Yan Ruixin , Zhang Yue , Hu Honglu , Ma Chen , Chen Ye , Xu Xingtao , Yang Juan , Voiry Damien , Tang Chuyang Y. , Fan Jun , Zeng Zhiyuan 
Published: May 2024

AbstractCapacitive deionization (CDI) has emerged as a promising technology for freshwater recovery from low‐salinity brackish water. It is still inapplicable in specific scenarios (e.g., households, islands, or offshore platforms) due to too low volumetric adsorption capacities. In this study, a high‐density semi‐metallic molybdenum disulfide (1Tʹ‐MoS2) electrode with compact architecture obtained by restacking of exfoliated nanosheets, which achieve high capacitance up to ≈277.5 F cm−3 under an ultrahigh scan rate of 1000 mV s−1 with a lower charge‐transfer resistance and nearly tenfold higher electrochemical active surface area than the 2H‐MoS2 electrode, is reported. Furthermore, 1Tʹ‐MoS2 electrode demonstrates exceptional volumetric desalination capacity of 65.1 mgNaCl cm−3 in CDI experiments. Ex situ X‐ray diffraction (XRD) reveal that the cation storage mechanism with the dynamic expansion of 1Tʹ‐MoS2 interlayer to accommodate cations such as Na+, K+, Ca2+, and Mg2+, which in turn enhances the capacity. Theoretical analysis unveils that 1Tʹ phase is thermodynamically preferable over 2H phase, the ion hydration and channel confinement also play critical role in enhancing ion adsorption. Overall, this work provides a new method to design compact 2D‐layered nanolaminates with high‐volumetric performance for CDI desalination.
Transparent Recombination Layers Design and Rational Characterizations for Efficient Two‐Terminal Perovskite‐Based Tandem Solar Cells
Authors: Lin Yuexin , Yang Wenhan , Gu Hao , Du Fenqi , Liao Jinfeng , Yu Dejian , Xia Junmin , Wang Haibin , Yang Shengchun , Fang Guojia , Liang Chao 
Published: May 2024

AbstractTwo‐terminal (2T) perovskite‐based tandem solar cells (TSCs) arouse burgeoning interest in breaking the Shockley–Queisser (S–Q) limit of single‐junction solar cells by combining two subcells with different bandgaps. However, the highest certified efficiency of 2T perovskite‐based TSCs (33.9%) lags behind the theoretical limit (42–43%). A vital challenge limiting the development of 2T perovskite‐based TSCs is the transparent recombination layers/interconnecting layers (RLs) design between two subcells. To improve the performance of 2T perovskite‐based TSCs, RLs simultaneously fulfill the optical loss, contact resistance, carrier mobility, stress management, and conformal coverage requirements. In this review, the definition, functions, and requirements of RLs in 2T perovskite‐based TSCs are presented. The insightful characterization methods applicable to RLs, which are inspiring for further research on the RLs both in 2T perovskite‐based two‐junction and multi‐junction TSCs, are also highlighted. Finally, the key factors that currently limit the performance enhancement of RLs and the future directions that should be continuously focused on are summarized.
Integration of Multicomplex‐Based Pharmacophore Modeling and Molecular Docking in Machine Learning‐Based Virtual Screening: Toward the Discovery of Novel PI3K Inhibitors
Authors: Qiu Shuo , Jia Lei , Yuan Shiru , Cai Yanfei , Chen Yun , Jin Jian , Xu Lei , Yu Li , Zhu Jingyu 
Published: May 2024

AbstractThe phosphatidylinositol‐3 kinase (PI3K) pathway is a crucial intracellular signaling pathway within living cells. The hyperactivation of PI3K signaling cascades is a common occurrence in human cancers, rendering PI3K a promising therapeutic target. Although several PI3K inhibitors are already available on the market, the adverse side effects of current therapies continue to highlight the necessity for the development of novel PI3K inhibitors. In this study, a virtual screening strategy employing naïve Bayesian classification (NBC) models, based on multicomplex‐based molecular docking and pharmacophore modeling, is developed. First, the docking accuracy and scoring reliability of four docking software are assessed, and Glide demonstrated higher predictability for PI3K inhibitors. Second, pharmacophore models are generated based on the current reported PI3K‐inhibitor interactions, and five pharmacophore hypotheses displayed significant capability in discriminating active PI3K molecules from inactive ones. Subsequently, three NBC models are constructed based on molecular docking and/or pharmacophore models, and the validation results showed that the NBC model, combining multicomplex‐based molecular docking and pharmacophore, significantly improved the hit rate of virtual screening against PI3K. Finally, the optimal NBC model is employed for virtual screening against the ChEMBL database, leading to the identification of multiple molecules with high potential as active PI3K inhibitors.
Metabolic Recoding of NSUN2‐Mediated m5C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m5C‐ENO1 Positive Feedback Loop
Authors: Chen Baoxiang , Deng Yanrong , Hong Yuntian , Fan Lifang , Zhai Xiang , Hu Heng , Yin Siyuan , Chen Quanjiao , Xie Xiaoyu , Ren Xianghai , Zhao Jianhong , Jiang Congqing 
Published: May 2024

AbstractThe RNA modification, 5‐methylcytosine (m5C), has recently gained prominence as a pivotal post‐transcriptional regulator of gene expression, intricately intertwined with various tumorigenic processes. However, the exact mechanisms governing m5C modifications during the onset and progression of colorectal cancer (CRC) remain unclear. Here, it is determined that the m5C methyltransferase NSUN2 exhibits significantly elevated expression and exerts an oncogenic function in CRC. Mechanistically, NSUN2 and YBX1 are identified as the “writer” and “reader” of ENO1, culminating in the reprogramming of the glucose metabolism and increased production of lactic acid in an m5C‐dependent manner. The accumulation of lactic acid derived from CRC cells, in turn, activates the transcription of NSUN2 through histone H3K18 lactylation (H3K18la), and induces the lactylation of NSUN2 at the Lys356 residue (K356), which is crucial for capturing target RNAs. Together, these findings reveal an intriguing positive feedback loop involving the NSUN2/YBX1/m5C‐ENO1 signaling axis, thereby bridging the connection between metabolic reprogramming and epigenetic remodeling, which may shed light on the therapeutic potential of combining an NSUN2 inhibitor with immunotherapy for CRC.
Revealing the Role of Polyacrylonitrile for Highly Efficient and Stable Perovskite Solar Cells at Extremely Low Temperatures
Authors: Yang Zhiting , Wu Yukun , Yang Na , Yang Rui , Hao Yuying 
Published: May 2024

AbstractPerovskite solar cells (PSCs) are considered to be a promising candidate for near‐space applications due to their high specific power, excellent radiation resistance, and compatibility with flexible substrates. Nevertheless, the low‐temperature cycles impose considerable challenges to their long‐term stability. Herein, the extremely low‐temperature photovoltaic process of PSCs is investigated and the effect mechanisms of PAN (Polyacrylonitrile) as an additive are revealed. It is found that the additive PAN regulates perovskite lattice stress and stabilizes perovskite lattice structure and thus retards perovskite phase transition at low temperatures. Moreover, the PAN improves perovskite dielectric properties and ion migration activation energy and effectively passivates perovskite defects at low temperatures. Therefore, the carrier transport/extraction/collection abilities at low temperatures are enhanced effectively by alleviating exciton effect and increasing dielectric screening effect. Benefiting from these positive effects of PAN, the PAN‐modified device achieves a maximum efficiency of 24.34% at 150K and maintains 72% of its initial value after 120 thermal cycles (290‐130K). Also, the PAN‐modified flexible devices exhibit excellent bending stability and thermal cycle stability. This study provides a deep insight into understanding the extremely low‐temperature photovoltaic behavior of PSCs and demonstrates the potentiality of PAN additive strategy for achieving efficient and stable PSCs at low temperatures.
County‐level industrial composition of the labor force and drug overdose mortality rates in the United States in 2018–2021
Authors: Oh Sehun , Cano Manuel , Kim Yeonwoo 
Published: May 2024

AbstractBackgroundDrug mortality risks vary among industries, creating distinctive geographic patterns across US counties. However, less is known about how local labor market structure relates to drug overdose mortality amid the synthetic opioid era in the United States. This study investigates the relationship between industry‐specific job composition and drug overdose mortality at the county level while exploring how fentanyl's presence in illicit drug supplies may moderate the relationship.MethodsData were derived from the National Center for Health Statistics' Multiple Cause of Death files for the rates of drug overdose mortality of any intent, linked with four other sources on industry‐specific job shares, drug supply, and county‐level sociodemographic characteristics and opioid prescribing rates from the US Census Bureau, the CDC, and the Drug Enforcement Administration. Negative binomial regression models were employed to examine associations between county industry‐specific job composition and drug overdose mortality, with tests for moderating effects of state‐level fentanyl seizure rates.ResultsOur models indicate negative associations between job shares of manufacturing, retail trade, and educational services industries and drug overdose mortality. Positive associations were found for arts/entertainment/recreation and public administration. State‐level fentanyl seizure rates had moderating effects on administrative/support/waste management/remediation (A/S/WM/R) and educational services.ConclusionCounties with a higher concentration of arts/entertainment/recreation and public administration jobs need targeted efforts to mitigate drug‐related overdose risks. Additionally, areas with higher concentrations of A/S/WM/R service jobs, particularly where fentanyl seizure rates are higher, may require proactive harm reduction strategies for reducing overdose risks.
Workplace health culture and trust in the occupational health office: A descriptive study of meatpacking workers
Authors: Rowland Sheri , Ahmed Rishad , Roman Maria Jose Sanchez , Ramos Athena K. 
Published: May 2024

AbstractIntroductionWorker trust in employer‐provided occupational health services has not been explored in essential industries, such as meatpacking. The purpose of this study was to describe workplace health culture and trust in the occupational health office and highlight meatpacking workers' experiences with the occupational health office.MethodsMeatpacking workers were surveyed between February 2021 and October 2022. Descriptive statistics and nonparametric tests were used to explore trust across demographic variables, including workplace health culture. Thematic analysis was used to examine the short‐answer qualitative data.ResultsAmong workers who completed surveys (n = 731), health culture was rated low (M = 1.3 (0.73); possible range 0‐3). Trust in the occupational health office was also rated low (M = 8.2 (5.06); possible range 0–20). Workers' descriptions of interactions with the occupational health office were mostly unfavorable (287 negative opinion units; 97 positive opinion units) and primarily focused on quality of care, communication, the supervisor as gatekeeper to health services, and the prioritization of company interests.ConclusionMeatpacking worker health may be improved by building worker trust in the occupational health office. Suggested strategies include enhanced communication, protection of confidentiality, prioritization of worker well‐being, and promotion of a stronger health culture in plants and throughout the industry. Supporting workers without a regular healthcare provider to establish a relationship with a primary care provider of their choice is also recommended.
Are Australian students' academic skills declining? Interrogating 25 years of national and international standardised assessment data
Authors: Larsen Sally A. 
Published: May 2024

AbstractStandardised tests of academic basic skills are an established feature of contemporary Australian schooling. Assessment results are widely reported and directly influence educational policymaking. Furthermore, Australian national educational priorities are linked to educational system accountability via the results of standardised tests. Given the influence and importance of assessment data, this paper aimed to collate publicly available data from four assessment programmes undertaken by Australian students, and document long‐term trends in average achievement across all available assessments. Results are reported from three international assessments, the Progress in International Reading Literacy Study, the Trends in International Mathematics and Science Study and the Programme for International Student Assessment (PISA), along with the only Australian assessment, the National Assessment Program: Literacy and Numeracy. Of these four, only PISA demonstrated systematic declines in average scores over time. For the remaining three programmes, results in the primary school years showed initial improvements that were subsequently maintained over remaining iterations of the tests. In secondary school, students' average results neither declined nor increased appreciably over time. The consensus of the four largest assessment programmes undertaken by Australian students since 1995 thus fails to support the prevailing narrative of a broadscale decline in academic skills attainment.
Comparative studies between humans and golden Syrian hamsters via thromboelastography
Authors: Yang Ze , Xie Lili , Ba Jingjing , Zan Simin , Zhang Letong , Zhang Xinyi , Yu Yang 
Published: May 2024

AbstractBackgroundThromboelastography (TEG) is a widely utilized clinical testing method for real‐time monitoring of platelet function and the thrombosis process. Lipid metabolism disorders are crucial risk factors for thrombosis. The lipid metabolism characteristics of hamsters resemble those of humans more closely than mice and rats, and their relatively large blood volume makes them suitable for studying the mechanisms of thrombosis related to plasma lipid mechanisms. Whole blood samples from golden Syrian hamsters and healthy humans were obtained following standard clinical procedures. TEG was employed to evaluate coagulation factor function, fibrinogen (Fib) function, platelet function, and the fibrinolytic system.MethodsThe whole blood from hamster or healthy human was isolated following the clinical procedure, and TEG was employed to evaluate the coagulation factor function, Fib function, platelet function, and fibrinolytic system. Coagulation analysis used ACLTOP750 automatic coagulation analysis pipeline. Blood routine testing used XN‐2000 automatic blood analyzer.ResultsTEG parameters revealed that hamsters exhibited stronger coagulation factor function than humans (reaction time [R], p = 0.0117), with stronger Fib function (alpha angle, p < 0.0001; K‐time [K], p < 0.0001). Platelet function did not differ significantly (maximum amplitude [MA], p = 0.077). Hamsters displayed higher coagulation status than humans (coagulation index [CI], p = 0.0023), and the rate of blood clot dissolution in hamsters differed from that in humans (percentage lysis 30 min after MA, p = 0.02). Coagulation analysis parameters indicated that prothrombin time (PT) and activated partial thromboplastin time (APTT) were faster in hamsters than in humans (PT, p = 0.0014; APTT, p = 0.03), whereas the Fib content was significantly lower in hamsters than in humans (p < 0.0001). No significant difference was observed in thrombin time (p = 0.1949).ConclusionsIn summary, TEG could be used to evaluate thrombosis and bleeding parameters in whole blood samples from hamsters. The platelet function of hamsters closely resembled that of humans, whereas their coagulation function was significantly stronger.