bluuebunny/crossref_metadata_2025_split huggingface dataset:
The first evidence of alloparental feeding in a crevice‐nesting seabird, the little auk
Authors: Syposz Martyna , Devogel Marion , Grissot Antoine , Jakubas Dariusz , Wojczulanis‐Jakubas Katarzyna 
Published: April 2024

AbstractAn alloparent is an individual that cares for a young individual, but it is not its genetic parent. This behaviour is known in many species of animals, but some groups are still underreported. Here, we documented, in camera footage, the alloparental feeding of two chicks of the little auk, a crevice‐nesting seabird. This is the first evidence of this behaviour in the little auk despite similar monitoring undertaken between 2016 and 2022 and the second record for a crevice/burrow‐nesting seabird. We compared chicks that were fed by an alloparent to other chicks from the same year and explored reasons for the behaviour in the context of seabird breeding biology.
Alkyne Cyclotrimerisation, Acyclic Oligomerisation, and Transfer Hydrogenation Catalysed by a Titanium(IV) Phosphinoaryloxide Complex and its Redox Chemistry
Authors: Steiner Matthias R. , Jouikov Viatcheslav V. , Fischer Roland C. , Uher Johanna M. , y Medina Isabel‐Maria Ramirez , Hlina Johann A. 
Published: April 2024

AbstractThe reaction of sodium 2,4‐di‐tert‐butyl‐6‐(diphenylphos‐phino)phenolate (1, NaOArP) with TiIVCl4(THF)2 in a 2 : 1 molar ratio yielded TiIV(OArP)2Cl2 (2). The reduction of 2 with magnesium gave the dimeric titanium(III) compound [TiIII(OArP)2Cl]2 (3). In the presence of magnesium, compound 2 was found to catalyse the cyclotrimerization, acyclic oligomerisation, and hydrogenation of terminal alkynes. The complexes were characterised by single‐crystal X‐ray diffraction, optical spectroscopy, elemental analysis, and NMR or EPR spectroscopy, respectively.
The blood serum metabolome profile after different phases of a 4‐km cycling time trial: Secondary analysis of a randomized controlled trial
Authors: Azevedo Rafael A. , Cruz Ramon , Silva‐Cavalcante Marcos D. , Lima‐Silva Adriano E. , Bertuzzi Romulo 
Published: April 2024

AbstractIt has been assumed that exercise intensity variation throughout a cycling time trial (TT) occurs in alignment of various metabolic changes to prevent premature task failure. However, this assumption is based on target metabolite responses, which limits our understanding of the complex interconnection of metabolic responses during exercise. The current study characterized the metabolomic profile, an untargeted metabolic analysis, after specific phases of a cycling 4‐km TT. Eleven male cyclists performed three separated TTs in a crossover counterbalanced design, which were interrupted at the end of the fast‐start (FS, 600 ± 205 m), even‐pace (EP, 3600 ± 190 m), or end‐spurt (ES, 4000 m) phases. Blood samples were taken before any exercise and 5 min after exercise cessation, and the metabolomic profile characterization was performed using Nuclear Magnetic Resonance metabolomics. Power output (PO) was also continually recorded. There were higher PO values during the FS and ES compared to the EP (all p < 0.05), which were accompanied by distinct metabolomic profiles. FS showed high metabolite expression in TCA cycle and its related pathways (e.g., glutamate, citric acid, and valine metabolism); whereas, the EP elicited changes associated with antioxidant effects and oxygen delivery adjustment. Finally, ES was related to pathways involved in NAD turnover and serotonin metabolism. These findings suggest that the specific phases of a cycling TT are accompanied by distinct metabolomic profiles, providing novel insights regarding the relevance of specific metabolic pathways on the process of exercise intensity regulation.
Development and validation of a new multiplex panel using SNaPshot‐based DIP‐TriSNP markers for forensic DNA mixtures
Authors: Fan Qingwei , Li Ling , Yang Huiling , Xu Dongdong , Wang Yun , Jin Bo , Du Bing 
Published: April 2024

AbstractShort tandem repeat analysis is challenging when dealing with unbalanced mixtures in forensic cases due to the presence of stutter peaks and large amplicons. In this research, we propose a novel genetic marker called DIP‐TriSNP, which combines deletion/insertion polymorphism (DIP) with tri‐allelic single nucleotide polymorphism in less than 230 bp length of human genome. Based on multiplex PCR and SNaPShot, a panel, including 14 autosomal DIP‐TriSNPs and one Y chromosomal DIP‐SNP, had been developed and applied to genotyping 102 unrelated Han Chinese individuals in Sichuan of China and simulated a mixture study. The panel sensitivity can reach as low as 0.1 ng DNA template, and the minor contributor of DNA can be detected with the highest ratio of 19:1, as indicated by the obtained results. In the Sichuan Han population, the cumulative probability of informative genotypes reached 0.997092, with a combined power of discrimination of 0.999999998801. The panel was estimated to detect more than two alleles in at least one locus in 99.69% of mixtures of the Sichuan Han population. In conclusion, DIP‐TriSNPs have shown promising as an innovative DNA marker for identifying the minor contributor in unbalanced DNA mixtures, offering advantages such as short amplifications, increased polymorphism, and heightened sensitivity.
The pathway for achieving sustainable aviation fuel production in the Middle East and North Africa region
Authors: Abbas Ismail , Shaar Ali , El Osta Rola 
Published: April 2024

AbstractThe Middle East and North Africa (MENA) region faces significant challenges in the production of sustainable aviation fuel (SAF) due to high costs, limited feedstock availability, and underdeveloped infrastructure. However, the region has diverse feedstock options and can leverage existing refining capabilities and advanced conversion technologies for SAF production. Addressing these challenges requires research and development (R&D) collaboration, supportive policies, and international knowledge exchange. To promote the production of SAF in the MENA region, a comprehensive strategy is required that includes collaboration, policy alignment, research and development, infrastructure development, and training. Market incentives such as regulations and financial support can help drive demand for SAF. Collaborating with international organizations can improve knowledge sharing and promote sustainable practices. Research and development collaboration is crucial for innovation and establishing a strong SAF industry. Policy harmonization can create a supportive framework for investment and innovation. Monitoring and reporting mechanisms can ensure transparency and verify sustainability. By addressing these aspects, the region can become a leading hub for SAF production and contribute to a sustainable aviation industry.
A Comparison of In Vitro Metabolic Clearance of Various Regulatory Fish Species Using Hepatic S9 Fractions
Authors: Zercher Megan , Coral Jason A. , Nabb Diane , Powers Griselda , Jones Alan , Johanning Karla 
Published: April 2024

Abstract
Bioaccumulation predictions can be substantially improved by combining in vitro metabolic rate measurements derived from rainbow trout hepatocytes and/or hepatic S9 fractions with quantitative structure–activity relationship (QSAR) modeling approaches. Compared with in vivo testing guidelines Organisation for Economic Co-operation and Development (OECD) 305 and Office of Chemical Safety and Pollution Prevention (OCSPP; an office of the US Environmental Protection Agency) 850.1730, the recently adopted OECD test guidelines 319A and 319B are in vitro approaches that have the potential to provide a time- and cost-efficient, humane solution, reducing animal use while addressing uncertainties in bioaccumulation across species. The present study compares the hepatic clearance of the S9 subcellular fraction of rainbow trout, bluegill, common carp, fathead minnow, and largemouth bass, discerning potential differences in metabolism between different warm- and cold-water species. With refinements to the in vitro metabolic S9 assay for high-throughput analysis, we measured in vitro clearance rates of seven chemicals crossing multiple classes of chemistry and modes of action. We confirmed that data from rainbow trout liver S9 fraction metabolic rates can be utilized to predict rainbow trout bioconcentration factors using an in vitro to in vivo extrapolation model, as intended in the OECD 319B applicability domain per the bioaccumulation prediction. Also, we determined that OECD 319B can be applied to other species, modified according to their habitat, adaptations to feeding behavior, and environmental conditions (e.g., temperature). Once toxicokinetics for each species is better understood and appropriate models are developed, this method can be an excellent tool to determine hepatic clearance and potential bioaccumulation across species. The present study could be leveraged prior to or in place of initiating in vivo bioconcentration studies, thus optimizing selection of appropriate fish species. Environ Toxicol Chem 2024;43:1390–1405. © 2024 SETAC
Flowchart of methods employed for in vitro metabolism assessment in multiple fish species of regulatory relevance. NADPH = reduced nicotinamide adenine dinucleotide phosphate; GSH = glutathione; UDPGA = uridine diphosphate glucuronic acid; PAPS = 3′-phosphoadenosine-5′-phosphosulfate; std = standard; OECD TG = Organisation for Economic Co-operation and Development test guideline.
Acute Toxicity Testing of Pink Salmon (Oncorhynchus gorbuscha) with the Tire Rubber–Derived Chemical 6PPD-Quinone
Authors: Foldvik Anders , Kryuchkov Fedor , Ulvan Eva Marita , Sandodden Roar , Kvingedal Eli 
Published: April 2024

Abstract
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-quinone) is a widespread contaminant of emerging concern resulting from oxidation of 6PPD, which is an antidegradant substance added to tires. The recent identification of 6PPD-quinone as the cause of acute mortality in coho salmon has quickly motivated studies on 6PPD-quinone toxicity to other species. Subsequent findings have shown that 6PPD-quinone toxicity is highly species specific. Closely related species can differ widely in response to 6PPD-quinone from extremely sensitive to tolerant. Hence toxicity testing is currently the only way to establish whether a species exhibits 6PPD-quinone toxicity. We investigated the acute toxicity of 6PPD-quinone in pink salmon alevins (sac fry). This species has is the only Pacific salmon that so far has not been tested for 6PPD-quinone sensitivity. Fish were exposed in static water in eight treatments with initial concentrations ranging from 0.1 to 12.8 μg/L. Fish were observed for 48 h, and changes in concentrations of 6PPD-quinone were monitored throughout the experiment. No mortalities or substantial changes in behavior were recorded. Environ Toxicol Chem 2024;43:1332–1338. © 2024 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Effect of the catabolic control protein A of Lactiplantibacillus plantarum AR113 on its colonization invivo
Authors: Qin Wenfei , Zeng Yue , Hung Weilian , Sun Jiaqi , Xia Yongjun , Xiong Zhiqiang , Song Xin , Ai Lianzhong , Wang Guangqiang 
Published: April 2024

AbstractLactiplantibacillus plantarum is selective for carbohydrate utilization, which is primarily regulated by the catabolic control protein A (ccpA). To investigate the impact of carbohydrate metabolism on the in vivo colonization of L. plantarum AR113, we constructed a ccpA knockout strain (AR113ΔccpA). In vitro assays showed that AR113ΔccpA had a 0.34 decrease in maximum biomass, and a 2.63 h increase in hysteresis time compared to AR113. In a single administration, there was no significant difference in the number of AR113 and AR113ΔccpA in the mucus layers, and the number of AR113 was approximately 34‐times higher than AR113ΔccpA at 48 h in the intestinal lumen. Notably, the knockout of the ccpA gene did not affect the colonization time of AR113 in the intestine during continuous administration. Therefore, the present work demonstrated that the ccpA did not play a crucial role in the in vivo colonization time of AR113 and provided valuable insights into the role of carbohydrate metabolism in bacterial colonization time in vivo.
How to Improve Sustainability in Fused Filament Fabrication (3D Printing) Research?
Authors: Kalinke Cristiane , Crapnell Robert D. , de Oliveira Paulo R. , Janegitz Bruno C. , Bonacin Juliano A. , Banks Craig E. 
Published: April 2024

AbstractThis review aims to provide an overview of sustainable approaches that can be incorporated into well‐known procedures for the development of materials, pre‐ and post‐treatments, modifications, and applications of 3D‐printed objects, especially for fused filament fabrication (FFF). Different examples of conductive and non‐conductive bespoke filaments using renewable biopolymers, bioplasticizers, and recycled materials are presented and discussed. The main final characteristics of the polymeric materials achieved according to the feedstock, preparation, extrusion, and treatments are also covered. In addition to recycling and remanufacturing, this review also explores other alternative approaches that can be adopted to enhance the sustainability of methods, aiming to produce efficient and environmentally friendly 3D printed products. Adjusting printing parameters and miniaturizing systems are also highlighted in this regard. All these recommended strategies are employed to minimize environmental damage, while also enabling the production of high‐quality, economical materials and 3D printed systems. These efforts align with the principles of Green Chemistry, Sustainable Development Goals (SDGs), 3Rs (Reduce, Reuse, Recycle), and Circular Economy concepts.
Exploring the burden of postpartum depression in urban Bangladesh: Prevalence and its associations with pregnancy‐related factors from a cross‐sectional study
Authors: Al‐Mamun Firoj , Sultana Most Sabiha , Momo Marufa Akter , Malakar Jyotie , Bahar Saad Bin , Uddin Imtiaz , Murshida Murshida , Akter Mst. Morsheda , Begum Mst. Mohsina , Nodi Tasmin Sayeed , Al Habib Abdullah , Kaggwa Mark M. , Roy Nitai , Mamun Mohammed A. 
Published: April 2024

AbstractBackground and AimsPostpartum depression (PPD) is a globally recognized public health concern, yet research focusing on women in urban areas of Bangladesh remains unexplored. This study aimed to address this research gap by investigating the prevalence and associated factors of PPD within the first 2 years after childbirth.MethodsA cross‐sectional study was conducted, enrolling 259 women (26.66 ± 4.57 years) residing in urban areas who were attending healthcare delivery centers. Sociodemographic factors, child‐related issues, pregnancy‐related complications, and PPD using the Edinburgh Postnatal Depression Scale (EPDS) were used for data collection. Data analysis involved the application of χ2 tests and logistic regression analysis using SPSS software.ResultsThis study found a 60.6% prevalence of PPD using a cutoff of 10 (out of 30) on the EPDS scale. Logistic regression analysis identified several significant factors associated with PPD, including high monthly family income (odds ratio [OR] = 47.51, 95% confidence interval [CI]: 8.34–270.54, p < 0.001), income dissatisfaction (OR = 14.28, 95% CI: 4.75–42.87, p < 0.001), up to two gravidities (OR = 2.94, 95% CI = 1.25–6.90, p = 0.013), pregnancy‐related complications (OR = 2.70, 95% CI = 1.05–6.96, p = 0.039), increased antenatal care visits, and higher childbirth expenses.ConclusionThis study underscores the high prevalence of PPD among urban mothers in Bangladesh. The identified risk factors emphasize the need for targeted mental health initiatives, specifically tailored to support the vulnerable group. Implementing such initiatives can effectively address the challenges posed by PPD and enhance the well‐being of postpartum women in urban areas.
Spatiotemporal variability of streamflow in the Pearl River Basin: Controls of land surface processes and atmospheric impacts
Authors: Zhang Ying , Gan Jianping , Yang Qichun 
Published: April 2024

AbstractTo advance understanding of the spatiotemporal variability of the streamflow in the Pearl River Basin (PRB), we used the Soil and Water Assessment Tool model to simulate the water fluxes from 2010 to 2020 and to identify the underlying controlling mechanisms. The streamflow in the PRB is highly variable and controlled by complex land surface processes and atmospheric impacts over the heterogeneous terrain. Two key factors primarily govern the streamflow: (1) the location of the active precipitation zone, which is determined by the interaction between the monsoon path and uplifting effect of the terrain, and (2) the redistributions resulting from land use and soil characteristics. We observe distinct patterns in the different water fluxes across the different regions. Specifically, surface flow exhibits the highest activity within the precipitation zone. Lateral flow and actual evapotranspiration (AET) have the greatest intensity in the forests and in agricultural regions, respectively, and the aquifer flow is more active in areas with coarse soil textures. The land surface processes of the AET and aquifer retention significantly govern the temporal variability of the streamflow, contributing to the precipitation and streamflow being out of phase in the PRB. Based on the underlying mechanisms driving streamflow variability, we classify the PRB into three substreams: a drought‐prone upstream, a hydrologically active midstream, and a typhoon‐affected downstream, and each substream exhibits distinct spatiotemporal characteristics of streamflow. We find that the time series and probability distributions of the streamflow at different tributaries within each substream are similar. Each probability distribution is multimodal and can be decomposed into three unimodal distributions representing dry, transitional, and wet conditions. Specifically, the PRB features a large and steep dry mode, a flat transitional mode, and a short wet mode.
Predictive value of computed tomography radiomics combined with traditional imaging features in WHO/ISUP grading of clear cell renal carcinoma
Authors: Feng Yu‐Ning , Zhu Yu‐Hui , Feng Xiao‐Rong , Wu Ju‐Fang , Wei Di , Huang Guang‐Di , Jiang Yun‐Dan 
Published: April 2024

AbstractThe aim of the study is to investigate the preoperative prediction value of computed tomography (CT) radiomics combined with traditional imaging features in the grading of clear cell renal cell carcinoma (CCRCC) by extracting and analyzing the CT radiomics information of patients with CCRCC. One hundred thirty four patients with CCRCC who were admitted to our Hospital, Sun Yat‐sen University (Futian, Shenzhen), between June 2019 and June 2023 were enrolled in this study. According to the WHO/ISUP classification standard, the patients were divided into the high differentiation group (III + IV) and the low differentiation group (I + II); they were divided into the study group and the validation group, with a ratio of 7:3 and the best features of the validation group were screened to construct the radiomics model. There were significant differences in the radiomics scores between the high differentiation group and the low differentiation group of CCRCC (p < 0.05). Computed tomography radiomics combined with traditional imaging features has favourable effects on predicting the differentiation degree of CCRCC before surgery.
Nearly uniform prices of fresh produce products in US retail chains and implications
Authors: Dong Xiao , Astill Gregory 
Published: April 2024

AbstractThis study provides evidence that retail prices of US fresh produce (fruits and vegetables) and fresh meat products are similar across stores within the same chain even though unique characteristics of fresh produce products might lend to more localization in pricing. The results show the median price difference of fresh produce is 5% within‐chain stores compared to 20% between‐chain stores. Furthermore, the results show no significant differences in fresh produce prices between‐chain stores that serve areas of differing food access nor significant differences in chain prices between Metropolitan Statistical Areas with implications to federal nutrition programs.
Punch biopsies in tattooed skin: Complications and patient‐reported outcomes
Authors: Poelhekken Mila , Schornagel Ines J. , van der Bent Sebastiaan A. S. 
Published: April 2024

AbstractBackgroundDespite the popularity and usage of tattoos in modern society, various complications can occur such as allergic tattoo reactions, infections, tattoo removal complications and chronic granulomatous inflammatory tattoo reactions such as sarcoidosis. Histopathology of skin biopsies in tattoos is crucial in the diagnostic process of complications. As tattoos are frequently obtained for cosmetic reasons, cosmetic consequences of a skin biopsy in a tattoo are important. Remarkably, no studies have been performed regarding the consequences and expected outcome of taking a punch biopsy of tattooed skin.ObjectivesThe objective of this study is to report on the possible complications and patient‐reported cosmetic outcomes after punch biopsies in tattooed skin. Specifically, this study aims to assess the impact on appearance, symptoms and psychosocial burden of biopsies in tattooed skin, using the SCAR‐Q.MethodsPatients who underwent a punch biopsy of tattooed skin at the Tattoo Clinic in the Alrijne Hospital between 2021 and 2023 were included. To evaluate patient satisfaction of the biopsy scar the SCAR‐Q and a questionnaire regarding the recovery of the punch biopsy was used.ResultsThe final cohort consisted of 50 patients. Across all scales, the median scores on the SCAR‐Q questionnaire were consistent with the maximum score. Patients scored significantly better on the appearance scale when the biopsy was taken longer than 8 months ago. Two‐third of the patients reported no postbiopsy symptoms, with the remainder experiencing itch, pain or redness, which typically resolved within 10 days (88%). Remarkably, 42% of the patients reported the biopsy scar was not visible on the skin anymore. Scars on the lower extremities and trunk were significantly more frequently visible, as well as scars among patients aged 40 and above.ConclusionsThis study demonstrates that the cosmetic and psychological impact of punch biopsies in tattooed skin is minimal and the recovery is fast with minimal symptoms. For this reason, biopsies of tattooed skin should not be avoided in the diagnostic process.