bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of high-resolution manometry in a resource challenged service
Authors: Parker Mohammed A. , Gabriel Mogamad S. , Moolla Muhammed S. , Van Rensburg Christoffel J. , Moodley Desiree L. , Du Plessis Wesley P. , Abdelsalem Ahmad A. 
Published: February 2025

Background: Oesophageal high-resolution manometry (HRM) is commonly used in the evaluation of patients presenting with upper gastrointestinal tract symptoms where primary oesophageal motility disorders are suspected. At our hospital, one doctor can perform and interpret HRM, with the hospital serving a population of approximately 3 million people. There is a paucity of data on HRM findings in South Africa.Methods: This study included data from patients that underwent HRM between January 2018 and January 2023, using the hospitals electronic note-keeping system to access records. High-resolution manometry was performed for all patients using a water state catheter with 24 pressure channels. The Chicago classification version 3 was used for reporting.Results: A total of 210 patients were included in this study. The average age of patients included was 50 years (standard deviation [s.d.] ± 15.2) old with a female predominance (n = 149, 71.0%). Indications included gastroesophageal reflux disease (GORD) (65.7%), refractory heartburn (62.4%), dysphagia (37.6%), non-cardiac chest pain (16.7%), pre-procedurally (5.7%) and post-procedurally (14.8%). Many primary oesophageal motility disorders were observed, including ineffective oesophageal motility (20%), achalasia (11.4%), absent contractility (4.3%), oesophagogastric junction outflow obstruction (1.9%) and jackhammer oesophagus (1%). Normal findings accounted for 61%. The most common type of achalasia was type 1 (n = 16, 66%).Conclusion: This study, being the first of its kind in South Africa, highlights the role of HRM in the diagnosis of primary oesophageal motility disorders with ineffective oesophageal motility being the most common pathology and GORD being the most common indication for HRM. Achalasia type 1 was the common type diagnosed.Contribution: HRM, despite its scarce availability, remains an important diagnostic tool in evaluating gastrointestinal pathologies.
Fine‐tuning XLNet for Amazon review sentiment analysis: A comparative evaluation of transformer models
Authors: Shetty Amrithkala M. , D. H. Manjaiah , Aljunid Mohammed Fadhel 
Published: February 2025

AbstractTransfer learning in large language models adapts pretrained models to new tasks by leveraging their existing linguistic knowledge for domain‐specific applications. A fine‐tuned XLNet, base‐cased model is proposed for classifying Amazon product reviews. Two datasets are used to evaluate the approach: Amazon earphone and Amazon personal computer reviews. Model performance is benchmarked against transformer models including ELECTRA, BERT, RoBERTa, ALBERT, and DistilBERT. In addition, hybrid models such as CNN‐LSTM and CNN‐BiLSTM are considered in conjunction with single models such as CNN, BiGRU, and BiLSTM. The XLNet model achieved accuracies of 95.2% for Amazon earphone reviews and 95% for Amazon personal computer reviews. The accuracy of ELECTRA is slightly lower than that of XLNet. The exact match ratio values for XLNet on the AE and AP datasets are 0.95 and 0.94, respectively. The proposed model achieved exceptional accuracy and F1 scores, outperforming all other models. The XLNet model was fine‐tuned with different learning rates, optimizers (such as Nadam and Adam), and batch sizes (4, 8, and 16). This analysis underscores the effectiveness of the XLNet approach for sentiment analysis tasks.
Tetrahydrocurcumin-induced apoptosis of hepatocellular carcinoma cells involves the TP53 signaling pathway, as determined by network pharmacology
Authors: Bao Zhuo-Cong , Zhang Ye , Liu Zhao-Dong , Dai Hui-Jun , Ren Fu , Li Ning , Lv Shang-Yu , Zhang Yan 
Published: February 2025

BACKGROUND
Hepatocellular carcinoma (HCC) is a malignant disease with high incidence and mortality worldwide. This study focuses on the TP53 target protein to investigate the potential therapeutic effect of tetrahydrocurcumin (THC) on HCC and its mechanism of action. The research hypothesis is that THC can inhibit the proliferation, migration, and invasion of HCC cells, and promote their apoptosis by regulating the TP53 target protein.
AIM
To explore the mechanism by which THC inhibits HCC cell proliferation via the TP53 signaling pathway.
METHODS
Potential targets of THC and HCC were identified from multiple databases. The core targets were subjected to analyses using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases, and visualization processing, using the online platform Metascape to identify the key molecules and signaling pathways involved in the action of THC against HCC. The molecular mechanisms of action of THC against TP53 in the inhibition of HCC cells were verified using cell counting kit-8, Transwell, apoptosis, and western blotting assays.
RESULTS
Molecular docking results showed that THC had a high score for the TP53 target protein. In vitro experiments indicated that THC effectively inhibited the proliferation and migration of HCC cells, and affected the expression levels of TP53 , MDM2 , cyclin B , Bax , Bcl-2 , caspase-9 , and caspase-3 .
CONCLUSION
THC induces the apoptosis of HCC cells through the TP53 signaling pathway, thereby inhibiting their proliferation and migration.
Assessing the competitive dynamics of AI partnerships
Authors: Carugati Christophe , Kar Nicole 
Published: February 2025

Artificial intelligence (AI) partnerships have become a prevalent strategy in AI markets, enabling developers to access critical resources for developing and deploying AI models. As concerns over market concentration and potential anti-competitive practices by incumbent firms grow, competition authorities worldwide are intensifying their scrutiny of these partnerships, using a range of enforcement and regulatory tools. However, reviewing these partnerships presents new and complex competition challenges.
This paper first categorizes AI partnerships into five types based on their rationale, namely, expertise, data, compute, distribution and investment. It then explores key competition concerns identified through market studies and investigations, analysing them through the frameworks of merger laws, antitrust laws and relevant regulations. The paper concludes with policy recommendations, suggesting competition authorities ensure predictability in the application of merger control rules to provide legal certainty, make competition principles more actionable and develop pro-competitive and innovation-friendly regulations.
Eksplorasi Pengalaman Belajar Mahasiswa dalam Menggunakan Whatsapp sebagai Media Pembelajaran di Perguruan Tinggi
Authors: Alimah Isnaini Putri Laili Nur , Sumarni Sri , Isnantyo Fajar Danur 
Published: February 2025

Perkembangan teknologi memberikan perubahan pada proses pembelajaran. Dengan adanya teknologi, pendidik dan peserta didik dapat dengan mudah berinteraksi dan meningkatkan kualitas pendidikan pada jenjang perguruan tinggi. Saat ini, WhatsApp menjadi media pembelajaran yang paling banyak digunakan di perguruan tinggi dan memberikan pengalaman belajar yang baru untuk mahasiswa. Pengalaman menggunakan WhatsApp dinilai belum lebih baik jika tidak diiringi dengan pembelajaran tatap muka. Penelitian ini bertujuan untuk mengidentifikasi pengalaman belajar mahasiswa dalam menggunakan WhatsApp sebagai media pembelajaran, mengidentifikasi kendala yang dialami mahasiswa, mengidentifikasi strategi yang dilakukan mahasiswa untuk mengatasi kendala yang dialami, dan mengetahui pihak yang berperan membantu mahasiswa dalam menyelesaiakan kendala yang mereka alami. Penelitian ini merupakan penelitian kualitatif naratif inquiry. Sumber data penelitian ini meliputi mahasiswa Universitas Sebelas Maret Surakarta (UNS). Teknik pengambilan sampel dengan purposive sampling. Pengumpulan data dilakukan dengan catatan harian, wawancara dan dokumentasi. Hasil dari penelitian ini adalah mahasiswa mampu berpartisipasi aktif dalam pembelajaran, mudah mendapatkan materi pembelajaran dan membukanya kembali, mudah berkomunikasi serta mudah menyelesaikan tugas. Meskipun demikian, mahasiswa mengalami kendala yaitu miskomunikasi, tidak memiliki kuota, jaringan WIFI, dan materi sulit dipahami. Untuk mengatasi kendala, strategi yang dilakukan mahasiswa yaitu membaca ulang materi, bimbingan dosen, memastikan jaringan internet baik, dan diskusi teman belajar dengan pihak - pihak yang membantu mahasiswa dalam mengatasi kendala yaitu keluarga, kampus, teman belajar, dan dosen.
A study of the strategic branding techniques used by indian fmcg companies in the digital era
Authors: Manjula Srinivas, Bidyanand Jha  
Published: February 2025

Investigating how digital branding tactics impact consumer behavior is the goal of this study, which focuses on the FMCG (fast-moving consumer goods) sector in India. Considering social media's growing effect on purchasing choices, the research aims to examine the connections between brand memory, digital marketing, social media engagement, and consumer interaction with online content. The research used a survey to examine 500 customers' knowledge, engagement, and responses to several digital branding tactics. The purpose of the data collection was to evaluate the ways in which various digital strategies affect customer behaviour. The results indicate that a sizable portion of customers follow FMCG businesses on social media. Higher degrees of engagement with digital material have been linked to increased brand loyalty and a higher propensity to buy. Important digital branding techniques that were shown to be successful in influencing customer decisions were influencer endorsements, e-commerce agreements, tailored suggestions, and social media ads.
A RESISTÊNCIA JURÍDICA NA LUTA PELO DIREITO SOCIAL À MORADIA NO JUDICIÁRIO DE MATO GROSSO DO SUL - UM BREVE RELATO DA OCUPAÇÃO SÃO JOÃO EM TRÊS LAGOAS-MS
Authors: Alexandre de Moura Bocato Lucas , Nardoque Sedeval 
Published: February 2025

As ocupações nas cidades brasileiras demonstram problemas sociais existentes na questão de moradia, sobretudo déficit habitacional aliado às políticas públicas precárias de habitação social. Na maioria das vezes, as disputas por terra e moradia nas cidades brasileiras acabam em tribunais, onde o Poder Judiciário decide sobre a posse e propriedade das áreas ocupadas e o destino das famílias afetadas. Este artigo apresenta o caso da Resistência Jurídica da Ocupação São João, iniciada em duas áreas públicas municipais em Três Lagoas (MS), em junho de 2021. A metodologia utilizada envolveu a análise de bibliografia e dados estatísticos, bem como a análise dos processos judiciais em andamento no Tribunal de Justiça de Mato Grosso do Sul. O artigo destaca como as ocupações, no caso da São João, são uma forma de resistência política e jurídica diante das condições precárias de moradia nas cidades brasileiras, por vezes debatidas nas diversas instâncias do poder judiciário brasileiro.
PALAVRAS-CHAVE: Ocupações; Déficit habitacional; Resistência jurídica; Problemas Sociais; Habitação Social;
Private corruptie, publieke belangen
Authors: van Mourik T.P. (Thomas) 
Published: February 2025

Private corruptie, publieke belangen: de strafbaarstelling van niet-ambtelijke omkoping in de context van de internationale drugssmokkel
De strafbaarstelling van niet-ambtelijke omkoping is van oorsprong vooral gericht op medewerkers die in ruil voor steekpenningen hun werkgever bedriegen. Thans wordt deze strafbaarstelling echter ook ingezet in een andere context: de bestrijding van drugsmokkel via de Rotterdamse haven. Dat roept vragen op. Hoewel de strafbaarstelling geschikt lijkt om ook deze vorm van criminaliteit te bestrijden, is daarvoor wel vereist dat men blijft redeneren langs de essentie van deze bepaling.
Het algemene opschortingsrecht
Authors: Dammingh J.J. 
Published: February 2025

Het algemene opschortingsrecht. Bespreking van het proefschrift van mr. G.J. Boeve
Gert Jan Boeve promoveerde in 2024 op een dissertatie over het (algemene) opschortingsrecht van art. 6:52 BW. In deze bijdrage wordt het boek van Boeve over dit (ook) voor de praktijk zo belangrijke leerstuk besproken.
A Multicenter Study to Evaluate Diagnostic Accuracy by Pathologists Using the Aperio GT 450 DX in Local and Remote Viewing Stations
Authors: Borowsky Alexander D. , Miller Dylan V. , Bauer Thomas W. , Feddersen Richard M. , Gui Dorina , Hall Brian J. , Albro James E. , Lloyd Isaac E. , Bishop John W. , Darrow Morgan A. , Spigel James H. , Martin David R. , Reynolds Samuel J. , McConnell Thomas G. , Glassy Eric F. , Zuckerman Jonathan , Kallichanda Nathash S. , Zhou Xiaozhi , Lewis Jenny V. , Dayal Shubham , Chiweshe Joseph , Sutcu Aysegul Ergin , White Michael 
Published: February 2025

Context.—
The adoption of digital pathology may enable pathologists to perform primary diagnosis in both local and remote whole slide image viewing settings, improving logistics and convenience.

Objective.—
To test the performance of a new whole slide imaging system (Aperio GT 450 DX), both local intranet-based and remote internet-based viewing were compared with manual glass slide light microscopy.

Design.—
A total of 1161 curated cases, enriched with difficult clinical diagnoses, were enrolled in this accuracy study and digitally scanned on 3 Aperio GT 450 DX instruments at 3 clinical sites. Ten reading pathologists across the 3 study sites viewed images either locally (directly connected to the image server) or remotely (viewed over an internet connection). Each diagnosis was scored (concordant, minor, or major discrepancy) by a separate team of 3 adjudication pathologists. The diagnostic accuracy of the Aperio GT 450 DX was tested by comparing the whole slide image review diagnosis with the conventional light microscope manual slide review diagnosis.

Results.—
The difference in the major discrepancy rate between whole slide image review diagnosis and manual slide review diagnosis was 2.40% (95% CI, 1.40%–3.39%), meeting the predefined acceptance criterion of the 95% CI upper bound of 4% or less. Secondary end points were also met, including an upper bound of 7% or less and both local-only and remote-only upper-bound discrepancy rates of 4% or less. Major discrepancies were slightly lower for the remotely viewed cases (2.17%) compared with local direct server connection (2.61%), and time per read was not different.

Conclusions.—
The diagnoses made using the Aperio GT 450 DX, using both local and remote access image data, are noninferior to the diagnoses made using conventional light microscopy.
Pemanfaatan Media Sosial Sebagai Media Pembelajaran Pendidikan Agama Islam
Authors: Fujianti Indah 
Published: February 2025

Banyak hal telah berubah dalam kurun waktu milenium, termasuk perubahan dalam pendidikan dan aspek kehidupan lainnya. Dalam situasi ini, para pendidik harus beradaptasi dan mengikuti kemajuan teknologi dengan harapan dapat meningkatkan pengalaman belajar yang lebih efektif. Hal ini sesuai dengan tujuan penelitian, yaitu untuk menyelidiki secara rinci bagaimana media sosial digunakan untuk meningkatkan pengajaran Pendidikan Agama Islam. Penelitian ini menggunakan metodologi penelitian kepustakaan dan bersifat kualitatif dengan menganalisis 10 jurnal relevan dari sepuluh tahun terkahir. . Penelitian ini dilakukan dengan mengkaji jurnal-jurnal terindeks yang membahas kemajuan teknologi dan pendidikan. Data dianalisis dengan Teknik studi literatur untuk memperoleh temuan baru. . Hasil Penelitian ini menunjukan bahwa media social sangat membantu proses pembelajaran khususnya pendidikan Agama Islam. . Penelitian ini menegaskan pentingnya pendidik mengikuti perkembangan teknologi seperti menggunakan media social sebagai media pembelajaran agar terciptanya sebuah pembelajaran yang efektif dan menyenangkan.
Implementasi Teori Belajar Sosial Dalam Program Mute (Muhammad Teladanku) Untuk Pendidikan Karakter Akhlak Mulia Di MTsN 1 Sumedang
Authors: Hermansyah Hasbi , Nursobah Asep , Erihadiana Mohammad 
Published: February 2025

This research aims to examine the implementation of social learning theory in the Mute (Muhammad Teladanku) program at MTsN 1 Sumedang as an effort to form noble moral character in students. This program is designed with systematic stages, including planning, implementation and evaluation which focuses on integrating the moral values ​​of the Prophet Muhammad in learning. Through interactive media such as videos of the Prophet's stories and guidebooks, students are invited to understand, remember and apply the values ​​of honesty, patience and tolerance in everyday life. The research results show that the use of social learning theory-based learning methods that involve attention, retention, production, and motivation is effective in increasing student engagement and understanding. Additionally, this program utilizes educational technology to strengthen learning, especially in the context of distance learning. Program evaluation is carried out holistically, including cognitive, affective and psychomotor assessments, to measure the extent to which moral values ​​have been internalized by students. Integration of the moral values ​​of the Prophet Muhammad in the curriculum, both through Islamic Religious Education and thematic approaches in other subjects , supports the formation of students' characters who are intellectually intelligent and morally noble. With a contextual and project-based approach, this program succeeds in creating meaningful and applicable learning experiences for students.
Enhancing the Capacity of Forest Farmer Groups (KTH) Through the Payment for Environmental Services (PES) Model Scheme
Authors: Wahyullah Wahyullah , Arsyad Usman , Makkasau Ahmad Rifqi , Wahyuni Wahyuni , Amaliah Rizki , Molo Hasanuddin , Misto Misto , Rafrin Syaifullah , Haerani Nurul 
Published: February 2025

Payment for Environmental Services (PES) is an environmental service compensation activity conducted by Forest Programme IV (FP-IV), designed to be implemented in the Mamasa Sub-Watershed of the Saddang Watershed. The implementation of this PES plan will be collaborated with parties such as the Bakaru Watershed Forum, Hydroelectric power plant (PLTA), and Forest Farmer Groups (KTH) in selected villages over a 5-year contract. However, the challenge is that the target community lacks trust in PES activities and most refuse to join, making the formation of KTH Mappideceng problematic. The purpose of community service is to enhance the capacity of KTH Mappideceng based on the requirements and criteria established by the PES model scheme. The methods used include primary socialization (door-to-door) such as surveys, lectures, and discussions. The results of the community service activities in KTH Mappideceng, Betteng village, showed an increase in the number of members from 12 to 21, with 15 being new members and 6 being existing ones. After the socialization carried out by the team, enthusiasm and motivation to join increased; however, the intervention location and funding limitations were predetermined by the PES model mechanism (FP-IV).
ASSESSMENT OF BARRIERS AND DRIVERS TO ADOPTION OF FACILITIES MANAGEMENT IN TERTIARY INSTITUTIONS IN MINNA, NIGER STATE
Authors: ZUBAIRU, B  , MUHAMMAD, I. Y  , NURUDEEN, U.  
Published: February 2025

This study has established that studies have not yet been applied to any sector of the economy except for few that studied hotel facility management because most studies in Nigeria have mostly been devoted to clarifying what facilities management (FM) really entails and distinguishing it from the traditionally practiced property management and maintenance management. In order to address this issue, this study assessed the barriers and drivers to adoption of FMin tertiary institutions in Minna, Niger State. The study therefore adopted a quantitative research approach with the use of questionnaire survey considering 105 respondents from the tertiary institutions in Minna, Niger State. A total of 97 questionnaires were retrieved giving a response rate of 92.38. The study analysed data collected with the use of frequency count, percentage and Relative Importance Index (RII). Findings of the study revealed that the most severe barriers to the effective adoption of FM strategies in tertiary institutions are “Training the HR in the skill demanded by project” (RII = 0.86) and “Operational problems” (RII = 0.79); the most significant drivers for the effective adoption of FM strategies in tertiary institutions in Minna are “Good organisational structure” (RII = 0.83) and “Development effective policies, process and organizational structure” (RII = 0.80).; and the most effective strategies for enhancing the adoption of FMin the maintenance of building of tertiary institutions in Minna are “Procurement Strategy” (RII = 0.78), “Maintenance Planning” (RII = 0.76) and “Maintenance Records” (RII = 0.76). It was concluded that the barriers and drivers to adoption of FMin tertiary institutions in Minna, Niger State are very significant and could lead to improvement of building conditions provided specific strategies are implemented to mitigate the barriers and enhance the drivers. The study recommended that the management of tertiary institutions in Minna should develop a mechanism for the effective implementation of the strategies for enhancing the adoption of FM in the maintenance of their buildings.
Communication Mechanisms and Job Productivity Among Public Secondary School Teachers in Machakos County, Kenya
Authors: Muthengi Kimanzi Bernard , Otieno Dr. Daniel , Njuguna Prof. Felicita 
Published: February 2025

Purpose: The fundamental part of any school is staff communication and staff performance in teaching. When principals practice effective communication with their staff and recognize what each teacher contributes, productivity can be realized. This study aimed to determine the role of communication mechanisms in job productivity among secondary school teachers in Machakos County.
Methodology: The research used a correlation research design. The target population was the

5869 teachers and 396 principals in the 396 public secondary schools in Machakos County. The researcher used a simple

random sampling method to identify 97 teachers who formed the study sample. Data was collected using questionnaires. Quantitative data was analysed using descriptive statistics and Pearson Correlation Coefficient, while qualitative data was analysed through narrative analysis.
Results: The study findings indicated that communication mechanisms influenced job productivity. Further, correlation analysis indicated there was a significant positive relationship between communication mechanisms and job productivity (rho = 0.606, p-value < 0.05), among public secondary school teachers in Machakos County.
Implication: Training in communication process has ensured job productivity. Effective communication ensured job productivity in their schools. Lateral communication has improved the teachers’ job productivity. The study recommends that principals should shift towards a more inclusive and participatory communication model that empowers teachers to voice their opinions, share feedback, and contribute to decision-making processes.