bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Study to Evaluate the Effect of a Combined Approach of Yoga and Diet in High-risk Cardiovascular Subjects
Authors: Rao Aayushee , Kacker Sudhanshu , Saboo Neha 
Published: May 2024

Background:
Cardiovascular disease (CVD) is a group of disorders of the heart and blood vessels, including coronary heart disease, cerebrovascular disease, rheumatic heart disease, peripheral artery disease, congenital heart disease, deep vein thrombosis, and pulmonary embolism.

Aim:
The aim of this study was to assess cardiovascular risk factors and evaluate the effectiveness of combined approach of yoga and diet in reducing cardiovascular risk factors among high-risk subjects.

Materials and Methods:
This interventional study was conducted at RUHS College of Medical Sciences and Associated Hospitals, Jaipur, on the high-risk population of either sex in the age group of 40–70 years. QRISK3 web calculator was used as the method of measurement for outcome of interest. The combined approach of yoga intervention includes yogic asanas and pranayamas and dietary modification.

Results:
This study compared physiological parameters (blood pressure) and biochemical parameters (fasting blood sugar, glycosylated hemoglobin, lipid profile) at baseline, three months and six months after yoga and diet intervention in participants who were at high-risk of cardiovascular disease development in future and were found to be having significantly decreased systolic blood pressure (P=0.000), fasting blood glucose (P=0.000), glycosylated hemoglobin (HbA1C) (P=0.011), total cholesterol-high density lipoprotein ratio (P=0.000), low density lipoprotein (P=0.009), triglyceride (P=0.034), and QRISK3 Score (P=0.000) after combined approach of yoga and diet.

Conclusions:
This study concluded that the short-term combined approach of yoga-based life-style intervention and diet reduced cardiovascular risk factors in subjects at high-risk of developing cardiovascular disease.
Right upper lobe agenesis associated with dextroposition of heart and ectopic kidney in an adult patient attending pulmonary medicine outpatient department: A rare case report from South India
Authors: Jith Jisna , K Shyam , K Ayana , Raykar Priyadarshini S. 
Published: May 2024

Pulmonary agenesis is a rare congenital anomaly that results from the unsuccessful growth of the primitive lung buds. A case of lung agenesis was first reported in 1673 during an autopsy. Pulmonary agenesis includes agenesis, aplasia, and hypoplasia as the three most common types. The survival rate is <50% by the age of 5 years in case of agenesis. Fifty percent of the cases of lung agenesis are associated with various congenital defects such as cardiovascular, central nervous system, gastrointestinal, genitourinary, skeletal, Down syndrome, and Klippel–Feil syndrome.
Here is the case of a 28-year-old male who presented with on-and-off cough and dyspnea for 3 years. On systemic examination, the patient had signs suggestive of loss of right lung volume. Chest x-ray showed right side volume loss with ipsilateral mediastinal shift with compensatory hyperinflation of the left lung. Computed tomography (CT) thorax with abdomen was suggestive of dextroposition with absent right upper lobe parenchyma, right upper lobe bronchus, right upper lobe artery, and superior pulmonary vein with the absence of hemiazygos vein with ectopic left kidney in the pelvis. Early identification of pulmonary agenesis is vital in preventing fibrosis in patients with unilateral lungs which might develop as a result of recurrent chest infections. Caution and vigilance will lead to a good prognosis.
Barriers for Regular Yoga Practice among Adult Population of India
Authors: Verma Anita , Shete Sanjay Uddhav 
Published: May 2024

Introduction:
The prevalence of physical inactivity is growing at an alarming rate and is strongly associated with metabolic disorders. While the health consequences of physical inactivity are well-documented, identifying the factors which lead to physical inactivity in individuals is an important step. Therefore, the objective of this study was to explore the most common barriers in regular yoga practice.

Materials and Methods:
This cross-sectional study was conducted among 644 adult participants from Pune district, Maharashtra, India, during the International Day of Yoga celebration. The survey questionnaire was written in both English and Marathi. The questionnaire was divided into two parts, i.e., sociodemographic details and the most common reason for not being able to practice yoga regularly.

Results:
The results showed that physical illness was more common in females (n = 35, 29.7%) than males (n = 25, 6.1%). Not finding correct yoga teacher and lack of clarity regarding yoga was also found to be the most common barriers in females as compared to males. A greater proportion of females (n = 62, 52.5%) were unable to do yoga regularly due to other priorities. Other common factors which limited most of the participants from practicing yoga regularly were varying eating times, lack of motivation, and doubt regarding yoga benefits. The percentage of other barriers for practicing yoga regularly was negligible.

Conclusions:
The results of this study concluded that there are eight most common barriers for practicing yoga regularly among the study participants.
Handgrip Muscle Strength – Its Association with Blood Pressure in Healthy Young Adults
Authors: Bhattacharjya Jolly , Goswami Bobyjeet 
Published: May 2024

Background:
Blood pressure, an important physiological parameter, indicates a health hazard when its level increases beyond the standard reference level. Various exercise modules are prescribed for the prevention and treatment of hypertension, but questions have been raised on the beneficial effect of isometric weight training exercises on blood pressure. An important biomarker to assess muscle fitness is handgrip muscle strength. The association of handgrip muscle strength with different physiological parameters and diseases has already been established. However, the consistent result on the relationship between handgrip muscle strength and blood pressure is not available.

Aim and Objective:
The aim of the study is to find the relationship between handgrip muscle strength and endurance with blood pressure, if any, in healthy young individuals.

Materials and Methods:
In this cross-sectional study, muscle strength and endurance were measured using a handgrip dynamometer, and blood pressure was measured using a sphygmomanometer following the standard procedures. Statistical analysis was performed using the SPSS software. Descriptive statistics were used to calculate the mean. The Pearson’s correlation coefficient was used to assess the association. P < 0.05 was considered statistically significant.

Results:
In this study, 80 volunteers participated. We found a positive correlation between muscle strength with systolic blood pressure and a negative correlation with diastolic blood pressure. We had not found any correlation between muscle endurance with any component of blood pressure.

Conclusion:
It can be concluded from this study that with the increase in muscle strength, there is an increase in systolic blood pressure. Hence, exercises must be prescribed with caution.
A Cross-sectional Study of Public Health Workforce and Infrastructure at Subcenters in District Bandipora of Jammu and Kashmir, India
Authors: Kataria Ghulam Mustafa , Bhat Ashfaq Ahmad 
Published: May 2024

Introduction:
Adequate workforce and infrastructure as per the Indian Public Health Standards (IPHS) is essential for health-care service delivery at subcenters.

Objectives:
The objective is to assess the existing workforce and infrastructure availability at subcenters and identification of gaps between minimum requirement as per IPHS and actual availability of workforce and Infrastructure at subcenters.

Methods:
It was a cross-sectional observational study. Study units were subcenters. Fifty percent of subcenters of the district were selected using simple random sampling method. Check list prepared from IPHS facility survey formats was used for data collection and collected data were analyzed using Statistical Package for Social Sciences.

Results:
The health worker female was available in adequate numbers, whereas the health worker male was available in 3 subcenters only majority of the subcenters were operating from a rented building. A residential facility for staff was not available at any subcenter. Separate public utilities for males and females were available in only 5 subcenters.

Conclusion:
There is a significant gap in availability of workforce and infrastructure at subcenter as compared to IPHS.
A Comparison of the Effectiveness of Concentrated Growth Factors-Enriched Bone Graft Matrix (Sticky Bone) and Type-1 Collagen-Derived (DMBM) Xenograft Coated with a Resorbable-Guided Tissue Regeneration Membrane: A Clinico-Radiographic Study on Intrabony Defects
Authors: Singh Gaurav , Chauhan Shailendra S. , Sinha Aditya , Sharma Satendra , Sharma Ankita , Agrawal Ritu , Kumari Radha 
Published: May 2024

Background:
The main goals of periodontal treatment are to gain access to the diseased areas, reduce pocket depth, stop the disease’s progression, and then repair the periodontal tissues that have been harmed by the disease process. Our study compared the efficacy of Type-1 collagen-derived (DMBM) Xenograft Coated with a resorbable-guided tissue regeneration (GTR) membrane and enriched bone graft matrix with concentrated growth factors (CGFs) (Sticky Bone) in the treatment of periodontal infrabony defects.

Methodology:
The study included 40 patients with periodontal infrabony defects who were systemically healthy. According to clinical and radiographic measurements, two groups to which the defects were randomly assigned at the time of surgery Group II Type-1 collagen-derived (DMBM) xenograft coated with a resorbable GTR membrane and Group I-enriched bone graft matrix with CGFs (Sticky Bone).

Results:
At the 6month examination, probing pocket depth reduction was moderately significant in the Group I (7.43 ± 1.51 mm to 3.00 ± 1.53 mm) compared with the Group II (7.14 ± 0.69 mm to 3.00 ± 1.53 mm). The mean gains of clinical attachment were 8.29 ± 1.98 mm to 3.86 ± 1.46 mm in the Group I and 7.85 ± 0.69 mm to 4.53 ± 1.113 mm in the Group II. Radiographic defect depth reduction was slightly greater in the Group I compared with the Group II.

Conclusions:
According to the findings of this study, treating infrabony defects with unfavorable architecture using a Sticky Bone with CGF membrane in combination with bone graft has significantly improved all clinical parameters tested when compared to using a GTR membrane.
D-Dimer in Coronavirus Disease 2019 Pneumonia
Authors: Patil Shital , Toshniwal Sham , Khule Shubhangi 
Published: May 2024

Introduction:
Robust data are available regarding the role of D-dimer as a marker of coagulation abnormality in infectious, inflammatory, and malignant process. Its role in predicting coagulation abnormality in the currently ongoing coronavirus disease 2019 (COVID-19) pandemic is evolving. In present we have studied its role in predicting severity, coagulation, and vascular abnormalities such as deep-vein thrombosis (DVT) and pulmonary thromboembolism (PTE). We have also studied the role of D-dimer in the prediction of final radiological outcome as post-COVID lung fibrosis in follow-up.

Materials and Methods:
Prospective, observational study included 1000 COVID-19 cases confirmed with reverse transcription polymerase chain reaction. All cases were assessed with high-resolution computed tomography thorax, oxygen saturation, inflammatory marker as D-dimer at entry point and follow-up. Age, gender, comorbidity, use of bilevel positive airway pressure/noninvasive ventilation (BiPAP/NIV), and outcome as with or without lung fibrosis as per computed tomography (CT) severity were key observations. In selected cases, we have performed lower limb venous Doppler and CT pulmonary angiography to rule out DVT or PTE respectively. Statistical analysis is done by using Chi-square test.

Results:
Age (<50 and >50 years) and gender (male vs. female) has significant association with D-dimer level (P < 0.00001) and (P < 0.010) respectively. CT severity score at entry point with D-dimer level has significant correlation (P < 0.00001). D-dimer level has significant association with duration of illness (DOI) before hospitalization (P < 0.00001). Comorbidities have a significant association with D-dimer level (P < 0.00001). D-dimer level has a significant association with oxygen saturation (P < 0.00001). BIPAP/NIV requirement has a significant association with D-dimer level (P < 0.00001). Timing of BIPAP/NIV requirement during hospitalization has a significant association with D-dimer level (P < 0.00001). Follow-up D-dimer titer during hospitalization compared to normal and abnormal to entry point level has a significant association with post-COVID lung fibrosis, DVT and PTE (P < 0.00001).

Conclusions:
D-dimer is an easily available, and universally acceptable inflammatory marker, which has documented a very crucial role in COVID-19 pneumonia in predicting the severity of illness, and assessing response to treatment during hospitalization. D-dimer has an important role during interventions in the intensive care unit, as follow-up titers have a significant role in step-up or step-down interventions in critical care settings. Correlating D-dimer with variables like DOI, oxygenation status, and timing of BIPAP/NIV at the entry point is important to have a satisfactory treatment outcome.
Comparative Evaluation of the Effectiveness of the Two Herbal Desensitizing Toothpastes in the Relief of Dentinal Hypersensitivity
Authors: Bansal Disha , Mahajan Mrinalini 
Published: May 2024

Background:
Dentinal hypersensitivity is a sharp pricking pain occurring on exposure of the dentinal surface to the external stimuli such as hot, cold, air, tactile, and chemical. This study was conducted to compare the effectiveness of two herbal desensitizing pastes in the relief of dentinal hypersensitivity at different time intervals.

Materials and Methods:
Forty subjects (with two teeth per patient) were considered for this study and randomly divided into two groups: Group 1: Hiora K, herbal desensitizing toothpaste and Group 2: Dant Kanti medicated desensitizing toothpaste. Using tactile stimulus and air stimulus, the sensitivity scores were recorded on visual analog scale immediately, then at 2 weeks, and then at the end of 4 weeks and compared.

Results:
There was no significant difference in the distribution of tactile sensitivity score and air blast sensitivity score at baseline, immediately after application, after 2 weeks, and after 4 weeks between Groups 1 and 2.

Statistical Analysis:
Chi-square test was used for statistical analysis.

Conclusion:
Desensitizing pastes can be used as a safe, economical, and effective option in the management of dentinal hypersensitivity.
Determinants of Teachers’ Perception of Sickle Cell Disease (SCD) and Care of School Children Living with SCD in Anambra State Nigeria
Authors: Efobi Chilota Chibuife , Ajuba Ifeoma Clara , Ajator Chioma , Chilaka Ugochinyere Jane , Nri-Ezedi Chisom Adaobi 
Published: May 2024

Background:
Sickle cell disease (SCD)-related complications lead to school absenteeism and poor academic performance. Educators must be well-versed in the prevalent signs and symptoms of this disease, including first aid care and associated psychosocial factors to curb this trend.

Aim:
To determine teacher’s knowledge of SCD and factors that affect this knowledge and care of children with SCD.

Subjects and Methods:
This was a descriptive survey of all Anambra State teachers invited to a health seminar at the State Education Ministry. Following a verbal informed consent, a pre-tested questionnaire was administered with information on socio demographics, school cadre of employment, marital status, and perception and care of SCD school children retrieved. The correct responses were scored on a scale of 100%. Collated data were cleaned and analyzed using Python 3.10.0. P values of less than 0.05 were considered statistically significant.

Results:
The average age of the 182 responders was 44.2 ± 7.14 years. The majority (90.7%) of teachers were women with post-secondary academic degrees (76.4%). Approximately 57.1% of responders were elementary school teachers. Despite the fact that only 23 (12.6%) of the teachers had attended SCD courses in the past, a good number possessed a reasonable knowledge on SCD. Although the male instructors had less knowledge than females, this difference was not statistically significant (P = 0.142). The highest educational level, prior exposure to SCD seminars, and the type of class the teacher teaches (primary or secondary) were found to impact their awareness and care of SCD patients (P = 0.003, 0.025, and 0.04, respectively).

Conclusion:
More seminars and health conversations on SCD should be held for teachers, with special attention to teachers who work in public schools, male teachers, and those with less than a bachelor’s degree.
Neglected Multi-Articulate Chronic Tophaeceous Cyst
Authors: Obalum Dike Chijioke 
Published: May 2024

Gout is a metabolic disease characterised by acute or chronic arthritis and deposition of monosodium urate crystals around joint, bones, soft tissue and kidneys.
This is the case of a 51 year old man who re-presented with a nineteen year history of joint pains and five year history of multiple joint swellings. This followed his defaulting from follow up after an earlier presentation 16 years previously with acute gouty arthritis.
Clinical evaluation revealed a middle aged man with multiple swellings over the hands, ankles, feet, elbows and knees. Serum uric acid was very elevated and radiographs revealed large tophi involving multiple joints. Abdomino-pelvic ultrasound scan and renal function tests were normal.
He was subsequently treated with medications and had significant improvement with clear regression of the size of the tophi. This case demonstrates that delayed treatment of gout or neglected gout over time can lead to tophaceous gouty arthritis.
Elevated intraocular pressure due to spontaneous hemorrhage into the endplate capsule of a glaucoma drainage implant
Authors: Banashefski Bryana , Sidoti Paul A. , Tai Tak Yee Tania 
Published: May 2024

Abstract
Tube occlusion with elevation of the intraocular pressure (IOP) is a well-described complication of glaucoma drainage implant (GDI) surgery. Most commonly, obstruction occurs at the proximal tube tip from iris, vitreous, or blood. Further intervention is often required to remove the obstruction and reestablish aqueous outflow. Herein, we describe a patient in whom obstruction of the distal tube ostium by clotted blood from a spontaneous hemorrhage into the endplate capsule of an Ahmed Glaucoma Valve (AGV) resulted in severe IOP elevation. This is the first report in the literature of distal tube occlusion by blood from a spontaneous hemorrhage into the endplate capsule of a GDI. Prompt recognition of this entity is important for appropriate treatment planning and patient counselling.
Association of local anesthetic method and prostate volume with the occurrence of prostate biopsy complications
Authors: Tolani Musliu Adetola , Ahmed Muhammed , Hamza Babatunde Kolapo , Muhammad Muhammad Salihu , Bello Ahmad , Maitama Hussaini Yusuf 
Published: May 2024

Background:
Due to the invasive nature of prostate biopsy, it is associated with various complications. The study aimed to determine the association of local anesthetic method and prostate volume with the occurrence of these prostate biopsy complications.

Materials and Methods:
It was a prospective study carried out in 106 patients with indications for prostate biopsy. They were randomized into two equal groups receiving either intrarectal lidocaine gel or periprostatic nerve block. Prostate volume was determined using transrectal ultrasound, and patients were further divided into three prostate volume classes (20-40 ml, 40-100 ml, and ≥100 ml). Systematic sextant prostate biopsy was done, and the occurrence of complications (pain, bleeding, infection, and urinary retention) was documented. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software.

Results:
The pain scores of patients were similar irrespective of their prostate volume even with the use of different types of anesthesia. There was no significant tendency for the occurrence of bleeding, infection, and voiding complications when periprostatic nerve block or intrarectal lidocaine gel was used for pain relief. Postbiopsy cystourethritis was, however, significantly associated with the volume of the prostate (P = 0.006).

Conclusion:
The choice of local anesthesia does not affect the occurrence of complications following transrectal prostate biopsy. There is, however, a significant potential for the development of postbiopsy cystourethritis in patients with larger prostates.
Foreign bodies in the ear, nose, and throat of children - A 10 years' experiences at a tertiary care teaching hospital
Authors: Swain Santosh Kumar , Behera Ishwar Chandra , Nahak Bulu 
Published: May 2024

Background:
Foreign bodies (FBs) in the ear, nose, and throat are frequently encountered clinical entities among the children. These ear, nose, and throat FBs are often seen by pediatricians, primary care physicians, and otolaryngologists.

Aim of the Study:
The objective of this study is to analyze various types of FBs in the ear, nose, and throat among children and its clinical profile with its treatment in the pediatric age group.

Materials and Methods:
This descriptive retrospective study was carried out at a tertiary care teaching hospital. During 10-year period from April 2010 to May 2020, 452 pediatric patients with FB in the ear, nose, and throat were managed. The clinical profile and management of these children were analyzed. The clinical data were collected from the admission charts and clinic tickets.

Results:
In this study, the majority of the FBs were found in the nasal cavity, which constitutes 30.53%, whereas 28.31% found in the external auditory canal, 11.72% in the pharynx, 13.49% in the esophagus and 15.72% in laryngotracheobronchial (LTB) tract. The age ranges from 0 to 16 years, with a mean age was 7.21 years. The majority of the ear, nose, and throat FBs were found in the age group of 0–5 years. Out of the 452 cases, 243 (53.76%) were removed under general anesthesia. Vegetable seed was the most common FB in the nose. Coin was the most common FB in the esophagus, whereas vegetable seeds were the most common FB found in the bronchus. The open safety pin is a hazardous LTB FB.

Conclusion:
FBs in the ear, nose, and throat of children are common. The accurate diagnosis and treatment of the FBs in the pediatric age is often challenging. These FBs can be associated with significant morbidity and complications if not removed immediately.