bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Extended Metal Chain with the 2,7‐Bis(dipyridyldiamino)‐1,8‐naphthyridine (H4bdpdany) Ligand – The Longest Even‐Numbered Metal Chain Complex
Authors: Kuo Jau‐Huei , Tsao Ting‐Bin , Lee Gene‐Hsiang , Lee Hsuan‐Wei , Yeh Chen‐Yu , Peng Shie‐Ming 
Published: March 2011

AbstractA decanickel extended metal atom chain (EMAC) complex with a new pyridyl‐ and naphthyridyl‐modulated ligand (H4bdpdany) was synthesized. Analysis of the crystal structure of complex [Ni10(μ10‐bdpdany)4(NCS)2](PF6)2 (1) shows that all of the bdpdany4– ligands bind the metal in an all‐syn conformation, and structural data reveals short Ni···Ni distances in the range 2.36–2.23 Å. Temperature‐dependent magnetic measurements performed on two independent high‐spin nickel(II) ions of complex [Ni10(μ10‐bdpdany)4(NCS)2](PF6)2 (1) demonstrate that the metal chain is antiferromagnetic. The longer distance between the two terminal high‐spin nickel(II) ions relative to those in tetranickel and hexanickel strings causes a decrease in the magnitude of the antiferromagnetic interaction.
Temperature‐Induced Enhancement of Catalytic Performance in Selective Hydrogen Generation from Hydrous Hydrazine with Ni‐Based Nanocatalysts for Chemical Hydrogen Storage
Authors: Singh Sanjay Kumar , Lu Zhang‐Hui , Xu Qiang 
Published: March 2011

AbstractWe demonstrate here that Ni nanoparticles, which are inactive for the decomposition of hydrous hydrazine at room temperature, can exhibit drastically enhanced catalytic performance with an increase in reaction temperature to 323 K. At this reaction temperature, complete conversion of hydrous hydrazine with 100 % H2 selectivity can be achieved by alloying Ni and Pt with a Pt content as low as 1 mol‐%. This significant temperature effect coupled with the uniform alloy composition of Ni–Pt nanocatalysts results in the observed enhanced catalytic performance of the Ni–Pt nanocatalyst for hydrogen generation from hydrous hydrazine. In addition, evidence suggests that the Ni‐based bimetallic catalysts can be used to release five equivalents of H2 and one equivalent of N2 from an aqueous solution of hydrazine borane N2H4BH3.
A Catalytic Application of Co/Zr Heterobimetallic Complexes: Kumada Coupling of Unactivated Alkyl Halides with Alkyl Grignard Reagents
Authors: Zhou Wen , Napoline Jonathan Wesley , Thomas Christine M. 
Published: March 2011

AbstractTris(phosphanylamide) early/late heterobimetallic Zr/Co complexes, ClZr(R′NPR2)3CoI [R′ = iPr, R = Ph (1), R′ = 2,4,6‐trimethylphenyl, R = iPr (2), R′ = R = iPr (3)], have been utilized as catalysts for the cross‐coupling of alkyl halides with n‐octylmagnesium bromide. While yields are consistently higher for alkyl bromide substrates, it is found that these unusual heterobimetallic complexes are also active towards more challenging alkyl chloride substrates. This is particularly interesting in light of the fact that monometallic cobalt complexes are inert towards these substrates, suggesting that Zr also plays a role in catalysis. Radical trapping studies suggest that a one‐electron transfer radical oxidative addition pathway is operative.
Biohydrogenation intermediates are differentially deposited between polar and neutral intramuscular lipids of lambs
Authors: Jerónimo Eliana , Alves Susana P. , Alfaia Cristina M. , Prates José A. M. , Santos‐Silva José , Bessa Rui J. B. 
Published: March 2011

AbstractThe deposition of C18 fatty acids (FA), especially in rumen biohydrogenation intermediates, was studied using 36 lambs fed four diets with graded proportions of sunflower oil (SO) and linseed oil (LO). Lambs were fed one of four diets consisting on dehydrated lucerne with either: 6% SO, 4% SO plus 2% LO, 2% SO plus 4% LO and 6% LO. The profile of C18 FA was greatly affected by replacement of SO with LO in both lipid fractions. In PL, oil replacement led to an extensive substitution of 18:2n‐6 with 18:3n‐3 and cis‐9 18:1, resulting in a fairly constant degree of unsaturation of C18 FA in membrane PL. C18 FA were differentially incorporated in NL and PL. Cis‐isomers like cis‐11; cis‐12; cis‐15 18:1 and cis‐12, cis‐15 18:2 were preferentially incorporated in PL with the exception of cis‐9, cis‐15 18:2. Trans C18 FA, including CLA isomers, were preferentially incorporated in NL with the exception of cis‐11, trans‐13 18:2. The preferential deposition of biohydrogenation derived trans C18 FA, including CLA isomers in NL, suggests that their potential to change membrane FA composition and structure is low.
Biological responses of a simulated marine food chain to lead addition
Authors: Soto-Jiménez Martín F , Arellano-Fiore Claudia , Rocha-Velarde Ruth , Jara-Marini Martín E , Ruelas-Inzunza Jorge , Voltolina Domenico , Frías-Espericueta Martín G , Quintero-Alvarez Jesús M , Páez-Osuna Federico 
Published: March 2011

Abstract
This investigation sought to assess the biological responses to Pb along a simplified four-level food chain, from the primary producer, the microalgae Tetraselmis suecica, grown in a control medium with &lt; 1 µg/L of Pb and exposed to a sublethal dose (20 µg/L of Pb) and used as the base of a simulated food chain, through the primary-, secondary-, and tertiary-level consumers, namely, the brine shrimp, Artemia franciscana; the white-leg shrimp, Litopenaeus vannamei; and the grunt fish, Haemulon scudderi, respectively. Growth of Pb-exposed T. suecica was 40% lower than that of the control cultures, and survival of A. franciscana fed this diet was 25 to 30% lower than the control. No differences in the growth rates of Pb-exposed and control shrimp and fish and no gross morphological changes were evident in the exposed specimens. However, the exposed shrimp and fish had 20 and 15% higher mortalities than their controls, respectively. In addition, behavioral alterations were observed in exposed shrimp and fish, including reduction in food consumption or cessation of feeding, breathing air out of the water, reduction of motility, and erratic swimming. The negative correlation between Pb concentration in whole body of shrimp and fish and Fulton's condition factor suggested also that the exposed organisms were stressed because of Pb accumulation. Environ. Toxicol. Chem. 2011; 30:1611–1617. © 2011 SETAC
Synthesis, structure, and complexation behavior of 14‐ and 28‐membered partially unsaturated thiacrown ethers
Authors: Shimizu Toshio , Komatsuzaki Satoru , Hirabayashi Kazunori 
Published: March 2011

AbstractPartially unsaturated 14‐ and 28‐membered thiacrown ethers,3and4, which possess alternating Z‐carbon‐‐carbon double bonds and propylene chains, were synthesized by stepwise reactions. The crystal structure of larger cyclic compound4was determined by X‐ray crystallographic analysis. 14‐Membered thiacrown ether3was found to be more easily oxidized electrochemically than larger cyclic compound4and the corresponding saturated system. Compounds3and4isomerized at temperatures exceeding 100°C in solution to give cyclic compounds with E‐olefin moieties but were stable at 80°C in solution. Compound3formed 1:1 complexes with silver and copper ions, and4formed 1:2 complexes mainly in solution. A complex of3with mercury(II) chloride was isolated, and its crystal structure was determined by X‐ ray analysis. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 22:287–293, 2011; View this article online atwileyonlinelibrary.com. DOI 10.1002/hc.20678
Selenium‐catalyzed reductive cyclization and carbocyclization of 2,2′‐dinitrostilbenes with carbon monoxide: One‐shot synthesis of indolo[1,2‐c]quinazolinones
Authors: Umeda Rui , Morishita Shigeru , Nishiyama Yutaka 
Published: March 2011

AbstractWhen 2,2′‐dinitrostilbene derivatives were allowed to react with carbon monoxide in the presence of a catalytic amount of selenium, reductive cyclization and carbocyclization proceeded to give indolo[1,2‐c]quinazolin‐6(5H)‐ones, containing both indole and cyclic urea units, in moderate yields. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 22:571–575, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20685
The next generation air transportation system: An approach to function allocation
Authors: Landry Steven J. 
Published: March 2011

AbstractA method for function allocation was developed and applied to the conflict detection and resolution problem in the next generation air transportation system. The method identifies key capabilities required of agents, automated or human, to achieve the goals of the system through state‐based modeling. For conflict detection and resolution in the next generation air transportation system, those capabilities include the ability to accurately identify current separation, predict future losses of separation and collisions, and identify four‐dimensional trajectory changes that, when implemented, will result in proper future separation. The modeling method feeds into an analysis of potential levels of automation across four stages of information processing, yielding a taxonomy of possible function allocation schemes, which can then be analyzed with respect to system and operator performance needs. The taxonomy is identified and analyzed for the current and future conflict detection and resolution system in air traffic control. © 2011 Wiley Periodicals, Inc.
Effects of the workplace social context and job content on nurse burnout
Authors: Lee Jenny S.Y. , Akhtar Syed 
Published: March 2011

AbstractJob burnout is a continuing concern for human resource management, as it affects employee productivity and well‐being. In particular, the nursing profession is widely recognized as a stressful occupation that leads to burnout. The present study examines the relative significance of workplace social context in a health care setting and the job content of the nursing profession for influencing the three dimensions of job burnout: emotional exhaustion, depersonalization, and personal accomplishment (Maslach & Jackson, 1981). Data were collected through a questionnaire survey of a random sample of 1,190 nurses working in 43 public hospitals in Hong Kong. The results indicate that although both the workplace social context and job content have significant effects on burnout dimensions, the effects of the workplace social context were significantly stronger. In addition, the workplace social context had a significant negative effect on personal accomplishment, whereas job content influenced personal accomplishment positively. Implications of these findings are discussed in the context of devising management interventions for dealing with job burnout in the nursing profession. © 2011 Wiley Periodicals, Inc.
Modelling the regional climate and isotopic composition of Svalbard precipitation using REMOiso: a comparison with available GNIP and ice core data
Authors: Divine D. V. , Sjolte J. , Isaksson E. , Meijer H. A. J. , van de Wal R. S. W. , Martma T. , Pohjola V. , Sturm C. , Godtliebsen F. 
Published: March 2011

AbstractSimulations of a regional (approx. 50 km resolution) circulation model REMOiso with embedded stable water isotope module covering the period 1958‐2001 are compared with the two instrumental climate and four isotope series (δ18O) from western Svalbard. We examine the data from ice cores drilled on Svalbard ice caps in 1997 (Lomonosovfonna, 1250 m asl) and 2005 (Holtedahlfonna, 1150 m asl) and the GNIP series from Ny‐Ålesund and Isfjord Radio. The surface air temperature (SAT) and precipitation data from Longyearbyen and Ny‐Ålesund are used to assess the skill of the model in reproducing the local climate. The model successfully captures the climate variations on the daily to multidecadal times scales although it tends to systematically underestimate the winter SAT. Analysis suggests that REMOiso performs better at simulating isotope compositions of precipitation in the winter than summer. The simulated and measured Holtedahlfonna δ18O series agree reasonably well, whereas no significant correlation has been observed between the modelled and measured Lomonosovfonna ice core isotopic series. It is shown that sporadic nature as well as variability in the amount inherent in precipitation process potentially limits the accuracy of the past SAT reconstruction from the ice core data. This effect in the study area is, however, diminished by the role of other factors controlling δ18O in precipitation, most likely sea ice extent, which is directly related with the SAT anomalies. Copyright © 2011 John Wiley & Sons, Ltd.
Variation in curve numbers derived from plot runoff data for New South Wales (Australia)
Authors: Cao Hongxia , Willem Vervoort R. , Dabney Seth M. 
Published: March 2011

AbstractThe curve number method is a simple one parameter (the curve number) rainfall runoff model. While its theoretical underpinning has been questioned it remains a powerful hydrological tool in the absence of detailed data and is therefore used extensively in hydrological models. This study aims to characterize the variation in maximum retention values (S), which underlie curve numbers, for a range of agricultural treatments across a large spatial area in New South Wales (NSW), Australia. The data used for the analysis spans several decades of rainfall runoff observations. A range of different derivation methods result in variation in mean and variance of S. In particular, methods that emphasize the larger storms result in greater S and thus lower runoff. For larger spatial scales, emphasis on larger storms gives more reliable estimates of S. Systematic variation in S arises from variations in treatment, pre‐runoff soil moisture, rainfall depth, and variations in cover. On the basis of the analysis, a table of curve number values for different land uses found in NSW is presented.The resulting distributions of S and curve numbers provide guidance for rainfall runoff modelling studies in the agricultural important areas of NSW. Copyright © 2011 John Wiley & Sons, Ltd.
Spatiotemporal variability of drought and the potential climatological driving factors in the Liao River basin
Authors: Liu Xingcai , Xu Zongxue , Yu Ruihong 
Published: March 2011

AbstractSpatiotemporal characteristics of drought based on the Standardized Precipitation Index (SPI) in the Liao River basin (LRB) are investigated in this study. High autocorrelation in SPI seems to lend itself to drought prediction. Drought is becoming more frequent, widespread, and severe in the LRB during the past several decades. Major factors affecting drought in this basin are analysed by investigating relationship between SPI and several circulations including western Pacific Subtropical High (WPSH), East Asian Summer Monsoon (EASM) and El Niño‐Southern Oscillation (ENSO) indices. Different correlation patterns between WPSH indices and SPI are obtained. Several significant positive correlations between the area, intensity of WPSH and SPI are observed in the west and the centre of the study area, while negative correlations are observed in the east. Reverse patterns are observed in the correlation between the ridge of westward longitude of WPSH and SPI. Corresponding lag‐correlation is dominated by positive correlations between the area, intensity of WPSH and SPI, and by negative correlation between the ridge of westward longitude of WPSH and SPI. EASM is mainly negative related with drought in the east of the LRB. Significant positive correlation between ENSO and SPI is mainly located in the east while negative correlation is located in west of the basin. Lag‐correlation (with lags of 1 to 12 months) between them is also investigated and results show that significant negative correlation is located in a broad area extending from the west to the centre of the basin, while less positive correlation is observed with the increase of lags. The possibility of employing general circulation models (GCMs) for drought prediction is discussed based on the above analyses. Copyright © 2011 John Wiley & Sons, Ltd.
Effects of an avidin‐biotin binding system on Schwann cells attachment, proliferation, and gene expressions onto electrospun scaffolds
Authors: Feng Sha , Yan Zuoqin , Guo Changan , Chen Zhengrong , Zhang Kuihua , Mo Xiumei , Gu Yudong 
Published: March 2011

AbstractEffective Schwann cells (SCs) attachment is a prerequisite for the successful construction of tissue‐engineered nerve. The present study aimed to investigate the role of an avidin‐biotin binding system (ABBS) for neural tissue engineering. The attachment, proliferation, and morphology of biotinylated SCs on avidin‐treated scaffolds were examined, and the effects of avidin, biotin, and the avidin‐biotin binding system on SCs gene expressions were also studied. The results indicated that the attachment of biotinylated SCs onto avidin‐treated scaffolds was promoted obviously within a short time (10 min). Meanwhile, there were no great differences in terms of proliferation and morphology of SCs between the two groups after cultivation for 14 days. The gene expressions of S100, GDNF, BDNF, NGF, CNTF, and PMP22 were up‐regulated significantly by biotin rather than aligned scaffolds or avidin. The present study demonstrated that ABBS enhanced the attachment and maturation of SCs onto the electrospun scaffolds without adverse effects on the proliferation of SCs in the long term, suggesting the potential application of ABBS in the neural tissue engineering. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2011.
Hypoxia affects dendritic cell survival: Role of the hypoxia‐inducible factor‐1α and lipopolysaccharide
Authors: Naldini Antonella , Morena Emilia , Pucci Annalisa , Miglietta Diego , Riboldi Elena , Sozzani Silvano , Carraro Fabio 
Published: March 2011

AbstractDendritic cells (DC) are the most potent antigen‐presenting cells and during their life cycle they are exposed to different oxygen tensions. Similarly to inflamed and tumor tissues, lymphoid organs are characterized by a hypoxic microenvironment; thus, the modality by which hypoxia may affect DC is important for regulating both the quality and the intensity of the immune response. Here, we show that human monocyte‐derived DC, exposed to hypoxia, expressed high levels of the hypoxia‐inducible factor (HIF)‐1α, associated with upregulation of BNIP3 and BAX expression. This was paralleled with downregulation of the anti‐apoptotic molecule Bcl‐2, enhanced caspase‐3 activity and poly (ADP‐ribose) polymerase cleavage, along with cell death. Transfection of HIF‐1α siRNA protected DC from the effects of hypoxia. Of interest, when hypoxic DC were maturated with lipopolysaccharide (LPS), we did not observe an increased cell death, while HIF‐1α accumulation and BNIP3 expression were still significantly upregulated. In contrast with immature DC, mature DC expressed higher levels of Bcl‐2, and, more importantly, of phosphorylated Akt. Transfection of HIF‐1α siRNA to mature DC resulted in a significant upregulation of Akt phosphorylation as well. Moreover, inhibition of PI3K/Akt pathway resulted in an increased cell death of hypoxic mature DC. We may conclude that a prolonged exposure to hypoxia induces a cell death program which could be prevented by HIF‐1α inhibition and/or LPS maturation. Our results may contribute to further understand the physiology of DC and the molecular mechanisms involved in the survival of DC, with important implications in the regulation of the immune response. J. Cell. Physiol. 227: 587–595, 2012. © 2011 Wiley Periodicals, Inc.
BDNF regulates GLAST and glutamine synthetase in mouse retinal Müller cells
Authors: DAI MIN , XIA XIAO‐BO , XIONG SI‐QI 
Published: March 2011

AbstractThis study investigated whether brain‐derived neurotrophic factor (BDNF) regulates the L‐glutamate/L‐aspartate transporter (GLAST) and glutamine synthetase (GS) in mouse retinal Müller cells (RMCs) under normal and hypoxic conditions. Mouse RMCs were treated with recombinant human BDNF (50, 75, 100, 125, or 150 ng/ml) for 24 h or underwent hypoxia induced by CoCl2 (125 µM; 6, 12, 24, 48, or 72 h). An additional group underwent combined treatment with BDNF (100 ng/ml; 24, 48, 72, or 96 h) and CoCl2 (125 µM/ml; 72 h). GLAST and GS mRNA and protein expression, L‐[3,4‐3H]‐glutamic acid uptake, and apoptosis were assessed. BDNF dose‐dependently up‐regulated GLAST and GS mRNA and protein and increased glutamate uptake. Similarly, in early‐stage CoCl2‐induced hypoxia, GLAST and GS were up‐regulated and glutamate uptake increased, but these decreased over time. BDNF also up‐regulated GLAST and GS and increased glutamate uptake when RMCs under CoCl2 induced hypoxic condition. However, BDNF treatment 24 h before CoCl2 had no effect on GLAST or GS expression. CoCl2 alone or combined with BDNF did not induce apoptosis. Hypoxia rapidly increased GLAST and GS expressions. This effect was transient, perhaps due to compensatory mechanisms that reduce GLAST and GS by 72 h. BDNF can up‐regulate GLAST and GS and increase glutamate uptake during hypoxia, and these functions may underlie its neuroprotective effects. J. Cell. Physiol. 227: 596–603, 2012. © 2011 Wiley Periodicals, Inc.
MARCKS dephosphorylation is involved in bradykinin‐induced neurite outgrowth in neuroblastoma SH‐SY5Y cells
Authors: Tanabe Atsuhiro , Shiraishi Mitsuya , Negishi Manabu , Saito Naoaki , Tanabe Mitsuo , Sasaki Yasuharu 
Published: March 2011

AbstractBradykinin (BK) plays a major role in producing peripheral sensitization in response to peripheral inflammation and in pain transmission in the central nerve system (CNS). Because BK activates protein kinase C (PKC) through phospholipase C (PLC)‐β and myristoylated alanine‐rich C kinase substrate (MARCKS) has been found to be a substrate of PKC, we explored the possibility that BK could induce MARCKS phosphorylation and regulate its function. BK stimulation induced transient MARCKS phosphorylation on Ser159 with a peak at 1 min in human neuroblastoma SH‐SY5Y cells. By contrast, PKC activation by the phorbol ester phorbol 12,13‐dibutyrate (PDBu) elicited MARCKS phosphorylation which lasted more than 10 min. Western blotting analyses and glutathione S‐transferase (GST) pull‐down analyses showed that the phosphorylation by BK was the result of activation of the PKC‐dependent RhoA/Rho‐associated coiled‐coil kinase (ROCK) pathway. Protein phosphatase (PP) 2A inhibitors calyculin A and fostriecin inhibited the dephosphorylation of MARCKS after BK‐induced phosphorylation. Moreover, immunoprecipitation analyses showed that PP2A interacts with MARCKS. These results indicated that PP2A is the dominant PP of MARCKS after BK stimulation. We established SH‐SY5Y cell lines expressing wild‐type MARCKS and unphosphorylatable MARCKS, and cell morphology changes after cell stimulation were studied. PDBu induced lamellipodia formation on the neuroblastoma cell line SH‐SY5Y and the morphology was sustained, whereas BK induced neurite outgrowth of the cells via lamellipodia‐like actin accumulation that depended on transient MARCKS phosphorylation. Thus these findings show a novel BK signal cascade—that is, BK promotes neurite outgrowth through transient MARCKS phosphorylation involving the PKC‐dependent RhoA/ROCK pathway and PP2A in a neuroblastoma cell line. J. Cell. Physiol. 227: 618–629, 2012. © 2011 Wiley Periodicals, Inc.