bluuebunny/crossref_metadata_2025_split huggingface dataset:
Borophene: Synthesis, Chemistry, and Electronic Properties
Authors: Wang Kai , Choyal Shilpa , Schultz Jeremy F. , McKenzie James , Li Linfei , Liu Xiaolong , Jiang Nan 
Published: June 2024

AbstractAs a neighbor of carbon in the periodic table, boron exhibits versatile structural and electronic configurations, with its allotropes predicted to possess intriguing structures and properties. Since the experimental realization of two‐dimensional (2D) boron sheets (borophene) on Ag(111) substrates in 2015, the experimental study of the realization and characteristics of borophene has drawn increasing interest. In this review, we summarize the synthesis and properties of borophene, which are mainly based on experimental results. First, the synthesis of borophene on different substrates, as well as borophane and bilayer borophene, featuring unique phases and properties, are discussed. Next, the chemistry of borophene, such as oxidation, hydrogenation, and its integration into heterostructures with other materials, is summarized. We also mention a few works focused on the physical properties of borophene, specifically its electronic properties. Lastly, the brief outlook addresses challenges toward practical applications of borophene and possible solutions.
Effect of multi‐tubes and eccentricity on melting performance of honeybee wax thermal energy storage system: A comprehensive numerical study and experimental validation
Authors: Khajuria Shubam , Vikas  , Kumar Himanshu , Yadav Ankit , Arıcı Müslüm 
Published: June 2024

AbstractWhen it comes to solar thermal power systems, a latent heat energy storage unit is one possible solution to the imbalance in supply and demand. On a shell‐tube type heat storage system, computational and experimental research was done to determine how to charge a heat storage system using honeybee wax‐biodegradable phase change material. This paper examines the impact of single, double, and triple inner heat transfer fluid tubes on the melting properties of bee wax in relation to vertical and horizontal eccentricity. Through the experimental examination of a lab‐scale prototype, the computational model was verified. A computational model was used to investigate the impact of eccentricity on different configurations for the melting process. Utilizing multiple tubes significantly shortened the charging time, according to the system analysis. In a vertically downward direction, melting time reduced as eccentricity increased. Compared to the single tube concentric case, the maximum melting time reduction for the single‐, double‐, and triple‐tube cases was 63.7%, 67.0%, and 68.34%, respectively.
A cross‐language analysis of disclosure properties: Evidence from Hong Kong
Authors: Do Chuong , Hu Kent Haochuan , Nabar Sandeep 
Published: June 2024

AbstractUsing the setting of Hong Kong, we examine how the linguistic properties of financial disclosure differ across languages. We exploit the requirement that firms listed on the Hong Kong Stock Exchange publish annual reports in two languages, English and Chinese. We find that for the same firm, English reports are more positive, convey more uncertainty, and focus more on the past and present and less on the future, than Chinese reports. We also find that English (Chinese) reports are more likely to manage their tone by varying the frequency of positive (negative) words. Finally, the stock market only reacts positively to tone management in Chinese reports. Overall, the results suggest that there are significant and fundamental differences in the linguistic properties of English and Chinese reports and that such differences have material implications for how investors perceive the reports.
Isolation and quantification of L1CAM‐positive extracellular vesicles on a chip as a potential biomarker for Parkinson's Disease
Authors: Li Danyu , Zou Siyi , Huang Ziyang , Sun Congcong , Liu Guozhen 
Published: June 2024

AbstractExtracellular vesicles (EVs) carry disease‐specific molecular profiles, demonstrating massive potential in biomarker discovery. In this study, we developed an integrated biochip platform, termed EVID‐biochip (EVs identification and detection biochip), which integrates in situ electrochemical protein detection with on‐chip antifouling‐immunomagnetic beads modified with CD81 antibodies and zwitterion molecules, enabling efficient isolation and detection of neuronal EVs. The capability of the EVID‐biochip to isolate common EVs and detect neuronal EVs associated with Parkinson's disease in human serum is successfully demonstrated, using the transmembrane protein L1‐cell adhesion molecule (L1CAM) as a target biomarker. The EVID‐biochip exhibited high efficiency and specificity for the detection of L1CAM with a sensitivity of 1 pg/mL. Based on the validation of 76 human serum samples, for the first time, this study discovered that the level of L1CAM/neuronal EV particles in serum could serve as a reliable indicator to distinguish Parkinson's disease from control groups with AUC = 0.973. EVID‐biochip represents a reliable and rapid liquid biopsy platform for the analysis of complex biofluids offering EVs isolation and detection in a single chip, requiring a small sample volume (300 µL) and an assay time of 1.5 h. This approach has the potential to advance the diagnosis and biomarker discovery of various neurological disorders and other diseases.
Causal inference under selection on observables in operations management research: Matching methods and synthetic controls
Authors: Yılmaz Övünç , Son Yoonseock , Shang Guangzhi , Arslan Hayri A. 
Published: June 2024

AbstractThe majority of recent empirical papers in operations management (OM) employ observational data to investigate the causal effects of a treatment, such as program or policy adoption. However, as observational data lacks the benefit of random treatment assignment, estimating causal effects poses challenges. In the specific scenario where one can reasonably assume that all confounding factors are observed—referred to as selection on observables—matching methods and synthetic controls can assist researchers to replicate a randomized experiment, the most desirable setting for drawing causal inferences. In this paper, we first present an overview of matching methods and their utilization in the OM literature. Subsequently, we establish the framework and provide pragmatic guidance for propensity score matching and coarsened exact matching, which have garnered considerable attention in recent OM studies. Following this, we conduct a comprehensive simulation study that compares diverse matching algorithms across various scenarios, providing practical insights derived from our findings. Finally, we discuss synthetic controls, a method that offers unique advantages over matching techniques in specific scenarios and is expected to become even more popular in the OM field in the near future. We hope that this paper will serve as a catalyst for promoting a more rigorous application of matching and synthetic control methodologies.
Mechanochemical Tailoring of Lignin Structure: Influence of Different Particle Sizes in the Organosolv Process
Authors: Bergrath Jonas , Zeppetzauer Franz , Rumpf Jessica , Kamm Birgit , Putz Robert , Kling Hans‐Willi , Schulze Margit 
Published: June 2024

AbstractThe autocatalyzed ethanolic organosolv process is gaining increasing attention for the sulfur‐free isolation of lignin, which is subsequently used as a renewable substitute for various fossil‐based applications. For the first time, the mechanochemical influence of seven different particle sizes of two different biomasses on the respective organosolv lignin structure is examined. Wine pruning (Pinot Noir) and wine pomace (Accent) are used for organosolv process with particle sizes ranging from 2.0–1.6 mm to less than 0.25 mm. As particle size decreases, the weight‐average molecular weight increases, while the total phenol content decreases significantly. Additionally, the distribution of the lignin‐typical monolignols and relevant substructures, as determined by two‐dimensional heteronuclear nuclear magnetic resonance spectra single quantum coherence (HSQC), is observed. The degree of grinding of the biomass has a clear chemical–structural influence on the isolated HG and HGS organosolv lignins. Therefore, it is crucial to understand this influence to apply organosolv lignins in a targeted manner. In the future, particle size specifications in the context of the organosolv process should be expressed in terms of distribution densities rather than in terms of a smaller than specification.
Amphiphilic Superspreading Polymer Membranes Prepared by Capillary Force‐Driven Self‐Assembly
Authors: Wei Zhong , Ru Yue , Jiang Haibin , Zhang Xiaohong , Qi Guicun , Liu Wenlu , Guo Zhaoyan , Zhang Liangdong , Wang Guoyu , Hu Chenxi , Jiang Chao , Wang Xiang , Li Binghai , Han Peng , Qiao Jinliang 
Published: June 2024

AbstractTo overcome the two main obstacles of large‐scale application of superspreading material, self assembly is used to prepare superspreading polymer membrane (SPPM) in this work. An amphiphilic SPPM is prepared by capillary force‐driven self assembly using PP melt‐blown nonwovens and polyvinyl alcohol (PVA). The prepared SPPM has low preparation cost and stable performance since self assembly needs low energy consumption, and the production is thermodynamically stable. By using cryo‐electron microscopy, transmission electron microscopy, X‐ray photoelectron spectrum and scanning electron microscope with energy dispersive X‐ray spectroscopy. It is proved that PVA is successfully assembled on the fiber surface of PP melt‐blown nonwovens. The prepared SPPM has excellent spreading performance, the “spreading times” of both water and oil are less than 0.5 s. They showed much superior performance compared to traditional materials when applied in oil‐water separation, seawater desalination, and ion separation. This work will definitely promote the development of self assembly, superspreading materials, and related sciences.
A Pragmatic Review on Spinal Cord Stimulation Therapy for Parkinson's Disease Gait Related Disorders: Gaps and Controversies
Authors: Hvingelby Victor S. , Carra Rafael B. , Terkelsen Miriam H. , Hamani Clement , Capato Tamine , Košutzká Zuzana , Krauss Joachim K. , Moro Elena , Pavese Nicola , Cury Rubens G. 
Published: June 2024

AbstractBackgroundParkinson's Disease (PD) is a progressive neurological disorder that results in potentially debilitating mobility deficits. Recently, spinal cord stimulation (SCS) has been proposed as a novel therapy for PD gait disorders. The highest levels of evidence remain limited for SCS.ObjectivesIn this systematic review and narrative synthesis, the literature was searched using combinations of key phrases indicating spinal cord stimulation and PD.MethodsWe included pre‐clinical studies and all published clinical trials, case reports, conference abstracts as well as protocols for ongoing clinical trials. Additionally, we included trials of SCS applied to atypical parkinsonism.ResultsA total of 45 human studies and trials met the inclusion criteria. Based on the narrative synthesis, a number of knowledge gaps and future avenues of potential research were identified. This review demonstrated that evidence for SCS is currently not sufficient to recommend it as an evidence‐based therapy for PD related gait disorders. There remain challenges and significant barriers to widespread implementation, including issues regarding patient selection, effective outcome selection, stimulation location and mode, and in programming parameter optimization. Results of early randomized controlled trials are currently pending. SCS is prone to placebo, lessebo and nocebo as well as blinding effects which may impact interpretation of outcomes, particularly when studies are underpowered.ConclusionTherapies such as SCS may build on current evidence and be shown to improve specific gait features in PD. Early negative trials should be interpreted with caution, as more evidence will be required to develop effective methodologies in order to drive clinical outcomes.
Biological‐equivalent‐dose‐based integrated optimization framework for fast‐energy‐switching Bragg peak FLASH‐RT using single‐beam‐per‐fraction
Authors: Zeng Yiling , Li Heng , Zhang Qi , Wang Wei , Liu Xu , Qin Bin , Pang Bo , Liu Muyu , Yang Kunyu , Quan Hong , Chang Yu , Yang Zhiyong 
Published: June 2024

AbstractBackgroundsWhen comparing the delivery of all beams per fraction (ABPF) to single beam per fraction (SBPF), it is observed that SBPF not only helps meet the FLASH dose threshold but also mitigates the uncertainty with beam switching in the FLASH effect. However, SBPF might lead to a higher biological equivalent dose in 2 Gy (EQD2) for normal tissues.PurposeThis study aims to develop an EQD2‐based integrated optimization framework (EQD2‐IOF), encompassing robust dose, delivery efficiency, and beam orientation optimization (BOO) for Bragg peak FLASH plans using the SBPF treatment schedule. The EQD2‐IOF aims to enhance both dose sparing and the FLASH effect.MethodsA superconducting gantry was employed for fast energy switching within 27 ms, while universal range shifters were utilized to improve beam current in the implementation of FLASH plans with five Bragg peak beams. To enhance dose delivery efficiency while maintaining plan quality, a simultaneous dose and spot map optimization (SDSMO) algorithm for single field optimization was incorporated into a Bayesian optimization‐based auto‐planning algorithm. Subsequently, a BOO algorithm based on Tabu search was developed to select beam angle combinations (BACs) for 10 lung cases. To simultaneously consider dose sparing and FLASH effect, a quantitative model based on dose‐dependent dose modification factor (DMF) was used to calculate FLASH‐enhanced dose distribution. The EQD2‐IOF plan was compared to the plan optimized without SDSMO using BAC selected by a medical physicist (Manual plan) in the SBPF treatment schedule. Meanwhile, the mean EQD2 in the normal tissue was evaluated for the EQD2‐IOF plan in both SBPF and ABPF treatment schedules.ResultsNo significant difference was found in D2% and D98% of the target between EQD2‐IOF plans and Manual Plans. When using a minimum DMF of 0.67 and a dose threshold of 4 Gy, EQD2‐IOF plans showed a significant reduction in FLASH‐enhanced EQD2mean of the ipsilateral lung and normal tissue by 10.5% and 11.5%, respectively, compared to Manual plans. For normal tissues that received a dose greater than 70% of the prescription dose, using a minimum DMF of 0.7 for FLASH sparing compensated for the increase in EQD2mean resulting from replacing ABPF with SBPF schedules.ConclusionsThe EQD2‐IOF can automatically optimize SBPF FLASH‐RT plans to achieve optimal sparing of normal tissues. With an energy switching time of 27 ms, the loss of fractionate repairing using SBPF schedules in high‐dose regions can be compensated for by the FLASH effect. However, when an energy switching time of 500 ms is utilized, the SBPF schedule needs careful consideration, as the FLASH effect diminishes with longer irradiation time.
Use of probiotics in preventing and treating excess weight and obesity. A systematic review
Authors: Torres Belén , Sánchez María C. , Virto Leire , Llama‐Palacios Arancha , Ciudad María J. , Collado Luis 
Published: June 2024

AbstractBackgroundThe prevalence of excess weight and obesity is increasing in an extremely concerning manner worldwide, with highly diverse therapies for current treatment. This review evaluated the scientific evidence of the past 10 years on the use of probiotics in treating excess weight and obesity in the absence of dieting.MaterialsA systematic review was conducted by searching for clinical trials on humans published in English in the PubMed, Scopus and Cochrane Central databases, using the combination of keywords “Overweight”, “Probiotics” and “Obesity”, and published between 2012 and 2022.ResultsSix published studies met the inclusion criteria. The review showed that, although there is a lack of consensus in the literature, the use of probiotics in the absence of dieting produced a significant reduction in body weight and body mass index in 66.6% of the reviewed studies, a significant reduction in waist circumference in 80.0% of the reviewed studies, and an improvement in total body fat mass and waist circumference.ConclusionsThis review showed evidence of a trend in preventing body weight gain and reducing weight through the use of probiotics in individuals with excess weight or obesity. A combination of various strains of the genera Bifidobacterium and Lactobacillus was the most effective.
Effect of tetrahydrofuran on the anionic copolymerization of 4‐trimethylsilylstyrene with isoprene
Authors: Fuchs Dominik A. H. , Wadgaonkar Shivani P. , Müller Axel H. E. , Frey Holger 
Published: June 2024

AbstractThe statistical anionic copolymerization of 4‐trimethylsilylstyrene (TMSS) with isoprene (I) in cyclohexane was investigated using in situ near‐infrared (NIR) spectroscopy in the presence of various amounts of the polar modifier tetrahydrofuran (THF). Polymers with narrow molecular weight distribution of 85–138 kg/mol and dispersities of 1.09–1.22 were obtained. By increasing modifier content, the reactivity ratios can be adjusted over a wide range from rTMSS < rI to rTMSS >> rI. Compared to the system styrene/isoprene (S/I) only a minute amount of modifier (0.5 eq THF relative to lithium) is sufficient to alter the reactivity ratios, resulting in an ideally random copolymerization, which validates the higher reactivity of TMSS compared to styrene. Using these reactivity ratios, molar and volume composition gradients were calculated. Additionally, the glass transition temperature and microstructure of the polyisoprene units were investigated via differential scanning calorimetry and proton nuclear magnetic resonance. The results are encouraging for the use of these materials in high‐end applications like membranes.
Effect of proton pump inhibitors versus histamine‐2 receptor antagonists on acute kidney injury in septic patients at high risk for developing stress ulcers
Authors: Fan Hua‐Ping , Zhou Yu , Chen Mei‐Li , Qiu Kun‐Hua , Feng Xue , Zhou Chao , Zhu Min‐Li , Huang Rong‐Zhong , Hu Tian‐Yang 
Published: June 2024

AbstractBackgroundTo compare the effects of proton pump inhibitor (PPI) and histamine‐2 receptor antagonist (H2RA) use on the occurrence of acute kidney injury (AKI) in septic patients at high risk for developing stress ulcers.MethodsUsing the Medical Information Mart for Intensive Care IV version 2.2 database, septic patients with high‐risk factors for stress ulcers (i.e., shock, coagulopathy, invasive mechanical ventilation, or chronic liver diseases) were included. Exposures included PPIs and H2RAs within 24 h of intensive care unit (ICU) admission or prior to ICU admission. The primary end point was severe sepsis‐associated AKI as defined by the Kidney Disease Improving Global Outcomes criteria stage 3 (KDIGO‐3). Propensity score matching (PSM) was performed to balance baseline characteristics. Multivariable Cox proportional hazards regression was used to estimate the effect size.Results4731 PPI users and 4903 H2RA users were included. After PSM, there were 1785 pairs exposed to PPIs and H2RAs. In the PSM cohort, the cumulative incident KDIGO‐3 rate was higher in the PPI group than in the H2RA group (log‐rank test, p = 0.009). Regression analyses showed that PPI exposure [adjusted hazard ratio 1.32, 95% confidence interval (CI) 1.11–1.58, p = 0.002] was associated with incident KDIGO‐3 compared with H2RA use. This association remained consistent in sensitivity analyses. Additionally, the PPI group had a higher need for kidney replacement therapy compared with the H2RA group (3.6% vs. 2.1%, P = 0.012).ConclusionsAmong septic patients at high risk for developing stress ulcers, PPI exposure was associated with incident KDIGO‐3 AKI compared with H2RA use.
Impacts of climate change and human activities on three Glires pests of the Qinghai–Tibet Plateau
Authors: Wang Zhicheng , Deng Yanan , Kang Yukun , Wang Yan , Bao Duanhong , Tan Yuchen , An Kang , Su Junhu 
Published: June 2024

AbstractBACKGROUNDThe range of Glires is influenced by human activities and climate change. However, the extent to which human activities and environmental changes have contributed to this relationship remains unclear. We examined alterations in the distribution changes and driving factors of the Himalayan marmot, plateau pika, and plateau zokor on the Qinghai–Tibet Plateau (QTP) using the maximum entropy (MaxEnt) model and a geographical detector (Geodetector).RESULTSThe MaxEnt model showed that the contribution rates of the human footprint index (HFI) to the distribution patterns of the three types of Glires were 46.70%, 58.70%, and 59.50%, respectively. The Geodetector results showed that the distribution pattern of the Himalayan marmot on the QTP was influenced by altitude and the normalized difference vegetation index (NDVI). The distribution patterns for plateau pikas and plateau zokors were driven by HFI and NDVI. Climate has played a substantial role in shaping suitable habitats for these three Glires on the QTP. Their suitable area is expected to decrease over the next 30–50 years, along with their niche breadth and overlap. Future suitable habitats for the three Glires tended to shift toward higher latitudes on the QTP.CONCLUSIONThese findings underscore the impacts of environmental and human factors on the distribution of the three Glires on the QTP. They have enhanced our understanding of the intricate relationships between Glires niches and environments. This can aid in identifying necessary interventions for developing effective early warning systems and prevention strategies to mitigate Glires infestations and plague epidemics on the QTP. © 2024 Society of Chemical Industry.
Synthesis and agricultural antimicrobial evaluation of new quinazoline derivatives containing both a piperazine linker and the N‐acetyl moiety
Authors: An Lian , Yang Lan , Yan Taisen , Yi Mingyan , Liu Songsong , Li Hong , Bao Xiaoping 
Published: June 2024

AbstractBACKGROUNDTo discover more efficient agricultural antimicrobial agents, a series of new quinazoline derivatives containing both a piperazine linker and the N‐acetyl moiety were prepared and assessed for their antibacterial and antifungal activities.RESULTSAll the target compounds were characterized by 1H and 13C NMR as well as high‐resolution mass spectrometry (HRMS), and the chemical structure of the most potent compound E19 incorporating a 4‐trifluoromethoxy substituent was clearly confirmed via single crystal X‐ray diffraction measurements. The bioassay results indicated that some compounds possessed notable inhibitory effects in vitro against the bacterium Xanthomonas oryzae pv. oryzicola (Xoc). For example, compound E19 had an EC50 (effective concentration for 50% activity) value of 7.1 μg/mL towards this pathogen, approximately 15‐ and 10‐fold more effective than the commercial bactericides thiodiazole copper and bismerthiazol (EC50 = 110.2 and 72.4 μg/mL, respectively). Subsequently, the mechanistic studies showed that compound E19 likely exerted its antibacterial efficacies by altering the cell morphology, increasing the permeability of bacterial cytoplasmic membrane, suppressing the production of bacterial extracellular polysaccharides and the extracellular enzyme activities (amylase and cellulase), and blocking the swimming motility of Xoc. Moreover, the proteomic analysis revealed that compound E19 could reduce the bacterial flagellar biosynthesis and decrease the flagellar motility by down‐regulating the expression of the related differential proteins.CONCLUSIONCompound E19 exhibited good potential for further development as a bactericide candidate for control of Xoc. © 2024 Society of Chemical Industry.