bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early peri‐implant endosseous healing of two implant surfaces placed in surgically created circumferential defects. A histomorphometric and fluorescence study in dogs
Authors: de Barros Raquel Rezende Martins , Novaes Arthur Belém , Queiroz Adriana , de Almeida Adriana Luisa Gonçalves 
Published: November 2011

AbstractObjectiveSeveral implant surfaces are being developed, some in the nanoscale level. In this study, two different surfaces had their early healing properties compared in context of circumferential defects of various widths.Material and methodsSix dogs had the mandibular premolars extracted. After 8 weeks, four implants were placed equicrestally in each side. One acted as control, while the others were inserted into sites with circumferential defects of 1.0, 1.5 and 2.0 mm wide and 5 mm deep. A nano‐modified surface was used on one side and a micro‐rough on the other. Bone markers were administered on the third day after implant placement and then after 1, 2, 4 weeks to investigate the bone formation dynamic through fluorescence analysis. Ground sections were prepared from 8‐week healing biopsies and histomorphometry was performed.ResultsThe fluorescence evaluation of the early healing showed numerically better results for the nano‐modified group; however this trend was not followed by the histomorphometric evaluation. A non‐significant numerical superiority of the micro‐rough group was observed in terms of vertical bone apposition, defect bone fill, bone‐to‐implant contact and bone density. In the intra‐group analysis, the wider defects showed the worse results while the control sites showed the best results for the different parameters, but without statistical relevance.ConclusionBoth surfaces may lead to complete fill of circumferential defects, but the gap width has to be considered as a challenge. The nano‐scale modification was beneficial in the early stages of bone healing, but the micro‐rough surface showed numerical better outcomes at the 8‐week final period.
Retention of implant‐supported zirconium oxide ceramic restorations using different luting agents
Authors: Nejatidanesh Farahnaz , Savabi Omid , Shahtoosi Mojtaba 
Published: November 2011

AbstractObjectiveThe aim of this study was to evaluate the retention value of implant‐supported zirconium oxide ceramic copings using different luting agents.Method and materialsTwenty ITI solid abutments of 5.5 mm height and ITI implant analogs were mounted vertically into autopolymerizing acrylic resin blocks. Ninety zirconium oxide copings (Cercon, Degudent) with a loop on the occlusal portion were made. All samples were airborne particle abraded with 110 μm Al2O3 and luted using different types of luting agents: resin cements (Clearfil SA, Panavia F2.0, Fuji Plus), conventional cements (Fleck's, Poly F, Fuji I), and temporary cements (Temp Bond, GC free eugenol, TempSpan) with a load of 5 Kg. (N = 10) All copings were incubated at 37°C for 24 h and conditioned in artificial saliva for 1 week, and thermal cycled for 5000 cycles 5–55°C with a 30‐s dwell time. The dislodging force of the copings along the long axis of the implant‐abutment complex was recorded using universal testing machine with 5 mm/min crosshead speed. Data were subjected to Kruskal–Wallis (α = 0.05) and Mann–Whitney tests with Bonferroni step down correction (α = 0.001).ResultsThere was significant difference between the mean rank retention values of different luting agents (P < 0.001). The resin cements showed the highest retention (Clearfil SA, 203.49 ± 52.86; Fuji Plus, 190.61 ± 48.00; Panavia F 2.0, 172.16 ± 70.76 N). The conventional cements had more retention than the temporary cements and glass ionomer cement (P < 0.001).ConclusionThe retention of zircona ceramic restorations, over ITI solid abutments may be influenced by the type of cement. The application of an MDP‐containing resin and resin‐modified glass ionomer luting agents increase the retentive value of implant‐supported zirconium oxide restorations.
Pattern and rate of progression of periodontal attachment loss in an urban population of South Brazil: a 5‐years population‐based prospective study
Authors: Haas Alex Nogueira , Gaio Eduardo José , Oppermann Rui Vicente , Rösing Cassiano Kuchenbecker , Albandar Jasim M. , Susin Cristiano 
Published: November 2011

AbstractAimThe aim of this 5‐years longitudinal study was to investigate the pattern and rate of periodontal attachment loss (PAL) progression in an urban population in South Brazil.MethodsIn 2001, a multistage probability sampling strategy was used to derive a representative sample of 1,465 dentate individuals from Porto Alegre, Brazil. Five years later, 697 dentate individuals (294M/403F, mean age: 37.9 ± 13.3) were available for follow‐up. PAL was assessed by calibrated examiners using a full‐mouth protocol. Estimates of proximal PAL progression and standard errors (SE) are reported.ResultsFifty‐six per cent (SE: 1.9) and 36% (SE: 1.8) of subjects showed PAL progression ≥3 mm affecting ≥2 and ≥4 teeth respectively. PAL progression ≥3 mm was mostly localized affecting 3.8 (SE: 0.2) teeth and 5.7 (SE: 0.3) sites. Annual PAL progression was, on average, 0.3 mm (SE: 0.01). Significant differences in PAL progression were observed according to age, gender, race and socioeconomic status. PAL progression increased with age reaching the highest progression rate in the 40–49 years cohort, and then decreased in older age groups. PAL progression was consistently higher among males and non‐Whites than females and whites.ConclusionA large proportion of this urban Brazilian sample was affected by PAL progression underscoring the need for health promotion initiatives aiming at preventing progression of destructive periodontal disease.
Translation, validation, and construct reliability of a Portuguese version of the Xerostomia Inventory
Authors: da Mata ADSP , da Silva Marques DN , Freitas FMF , de Almeida Rato Amaral JP , Trindade RTVMR , Barcelos FAD , Vaz Patto JM 
Published: November 2011

Oral Diseases (2012) 18, 293–298Objectives:  To generate and validate at pretest level a cross‐culturally adapted Portuguese version of Xerostomia Inventory (XI), a 11‐item questionnaire designed to measure specific xerostomia rating of patients complaints.Methods:  The original English version of the XI was translated into Portuguese following the guidelines for cross‐cultural adaptation of health‐related quality of life measures. Thirty patients with primary Sjögren syndrome were recruited for this study. The questionnaires were administered by trained and calibrated dental doctors to each patient. XI properties were examined including reliability, internal consistency, and test‐retest reliability, using Cronbach’s alpha, total and inter‐item correlation, and intra‐class correlation coefficients (ICC), respectively. Construct validity supported by objective measurements of xerostomia intra‐oral signs and salivary secretion was investigated. Alpha was set at 0.05. Informed consents and local ethical committee clearance were obtained.Results:  Internal consistency and test‐retest reliability were excellent (Cronbach’s α = 0.9; ICC range = 0.79–0.94). Scatterplot interpolation and Pearson correlation coefficient suggested the presence of a strong, negative, and significant correlation between salivation and the XI scores indicating construct validity.Conclusion:  The Portuguese version of the XI can be considered a reliable and valid instrument to measure patients’ xerostomia symptoms.
Proinflammatory cytokine levels in hyperlipidemic patients with periodontitis after periodontal treatment
Authors: Fentoğlu Ö , Kırzıoğlu FY , Özdem M , Koçak H , Sütçü R , Sert T 
Published: November 2011

Oral Diseases (2012) 18, 299–306Objective:  The aim of this study was to evaluate the effects of periodontal treatment on serum and gingival crevicular fluid (GCF) proinflammatory cytokine levels in hyperlipidemic patients with periodontitis.Materials and Methods:  Fifty‐two patients with hyperlipidemia and periodontitis and 28 systemically healthy controls with periodontitis (C) were included in the study. Hyperlipidemic groups were divided into two groups as suggested diet (HD) and prescribed statin (HS). The clinical periodontal parameters, fasting venous blood, and GCF samples were obtained, and serum tumor necrosis factor‐alpha (TNF‐α), interleukin (IL) 1‐beta, and IL‐6 levels were evaluated at baseline and at 3 months follow‐up (3MFU) after the completion of the non‐surgical periodontal treatment that included scaling and root planning.Results:  Percentage of bleeding on probing was significantly higher in the HS group than both the HD and C groups. In the HD and HS groups, there were significant decreases in serum IL‐6 and GCF TNF‐α levels between the 3MFU and baseline. A significant decrease was also found in GCF IL‐6 at the end of the study period in the HS group.Conclusion:  The combination of the periodontal therapy and antilipemic treatment may provide beneficial effects on the metabolic and inflammatory control of hyperlipidemia.
Retrospective Comparison of Semipermanent and Permanent Cementation of Implant‐Supported Single Crowns and FDPs with Regard to the Incidence of Survival and Complications
Authors: Schwarz Stefanie , Schröder Christin , Corcodel Nicoleta , Hassel Alexander Jochen , Rammelsberg Peter 
Published: November 2011

ABSTRACTPurpose: To retrospectively compare the fixation modalities semipermanent and permanent for all cemented single crowns and Fixed Dental Prostheses (FDPs) placed at the Department of Prosthodontics in the years 2002 to 2010 with regard to the incidence of survival and complications.Materials and Methods: Two hundred forty‐one patients (48.5% male, mean age 57.3 years) received 166 FDPs and 232 single crowns. A total of 50.6% of the FDPs and 54.7% of the single crowns were fixed using semipermanent cements. Aside from fixation, age, gender, type, location, and material of the suprastructures were assessed as possible factors affecting complications, namely de‐cementation, chipping, framework, or abutment fracture.Results: During an observation period of up to 6.6 years (mean 2.24 years; standard deviation 1.38), the survival rates were 96.4% and 100% for FDPs (semipermanent/permanent cementation), and 98.4% and 92.4% for single crowns (semipermanent/permanent). The success rates achieved, counting every complication, for the FDPs were 61.9% and 70.7% (semipermanent/permanent) and for single crowns were 75.6% and 77.1% (semipermanent/permanent). The cement used had a significant effect on loss of retention of the FDPs (p = .006), but no significant effect on the retention of the single crowns. Cementation procedure exhibited no significant impact on chipping for both FDPs and single crowns. The frequency of framework or abutment fractures was too low for further statistical analyses.Conclusion: Both semipermanent and permanent cementation of FDPs and single crowns resulted in high survival rates. Within the limitations of the study design, because of the amount of chairside aftercare required, implant‐borne FDPs could be recommended for permanent cementation.
Porcine‐Derived Xenograft Combined with a Soft Cortical Membrane versus Extraction Alone for Implant Site Development: A Clinical Study in Humans
Authors: Festa Vincenzo Maria , Addabbo Francesco , Laino Luigi , Femiano Felice , Rullo Rosario 
Published: November 2011

ABSTRACTBackground: An adequate alveolar crest is essential for implant placement in terms of esthetics and function. The objective of this randomized clinical trial was to compare the preservation of the alveolar ridge dimensions following tooth extraction using porcine‐derived xenograft combined with a membrane versus extraction‐alone (EXT) sites.Methods: Fifteen patients who required double extraction of contralateral premolars and delayed implant placement were randomly selected to receive both ridge‐preservation procedure and EXT. The test sites (alveolar ridge preservation [ARP]) included 15 sockets treated using a corticocancellous porcine bone xenograft (OsteoBiol® Gen‐Os; Tecnoss srl, Giaveno, Italy) associated with a soft cortical membrane (OsteoBiol® Lamina; Tecnoss srl), while the corresponding control sites (EXT) were left without grafting for EXT. Horizontal and vertical ridge dimensions were recorded at baseline and 6 months after extractions.Results: After 6 months, the EXT sites showed a significantly greater reabsorption of the buccolingual/palatal dimension of the alveolar ridge (3.7 ± 1.2 mm) compared with the ARP sites (1.8 ± 1.3 mm). The mean vertical ridge height reduction in the control sockets was 3.1 ± 1.3 mm at the buccal sites and 2.4 ± 1.6 mm at the lingual sites compared with 0.6 ± 1.4 and 0.5 ± 1.3 mm, respectively, in the test sockets. The differences between test and control sockets were not significant for the mesial and distal measurements.Conclusions: The placement of a porcine xenograft with a membrane in an extraction socket can be used to reduce the hard tissue reabsorption after tooth extraction compared with EXT.
EFFECT OF IRRADIATION DOSE ON PHYSICAL, FUNCTIONAL AND PASTING PROPERTIES OF COWPEA (VIGNA UNGUICULATA [L.] WALP) CULTIVARS
Authors: FALADE KOLAWOLE O. , KOLAWOLE TITILAYO A. 
Published: November 2011

ABSTRACTCowpea grains, stored as dry seeds, form an enormous reserve of foodstuff in the semi‐arid tropics covering Asia, Africa, Central and South America. Effect of γ‐irradiation on seed color, functional and pasting properties of six selected cowpea cultivars was investigated. Color (L*a*b*) of non‐ and γ‐irradiated cowpea cultivars was measured, and the deltachroma (ΔC), color difference (ΔE) and hue angle were calculated. Functional and physicochemical (pasting) of the milled cowpeas were determined using standards methods and rapid visco‐analyzer, respectively. Generally, L*, a* and b* values of cowpea seeds were significantly (P ≤ 0.05) affected by irradiation dose. Calculated chroma, color intensity and hue angle varied with cultivar and γ‐irradiation dose. Oil absorption capacities of the nonirradiated and irradiated cowpea flours varied from 1.08 to 1.30 and 0.94–1.20 g oil/ g sample, while the water absorption capacities ranged from 1.59 to 2.00 and 1.58–2.01 g water/g sample, respectively. Nonirradiated cowpea flours showed higher pasting properties (peak, trough, breakdown, final and setback viscosities) than the irradiated cowpea. Aside from breakdown viscosity, the pasting properties decreased significantly (P < 0.05) with increased γ‐irradiation dose. The IT96D‐610 and IT97K‐568‐18 cultivars showed significantly higher peak, trough, final and setback viscosities compared with other cowpeas.PRACTICAL APPLICATIONSExposing foods to ionizing radiations such as gamma rays emitted from the radioisotopes 60Co and 137Cs, or high energy electrons and X‐rays produced by machine sources, helps to destroy microorganisms or insects present in the food. Depending on the absorbed radiation dose, various effects can be achieved resulting in reduced storage losses, extended shelf life and/or improved microbiological and parasitological safety of foods. Microorganisms and pests can no longer proliferate and continue their activities, and insect gametes do not survive or become incapable of proliferation. Large quantities of stored legumes are lost annually as a result of mould contamination and insect attack which continues after harvesting even to storage. Irradiation of cowpea is a viable alternative to the use of chemicals, which have adverse effects on both food and environment, associated with residues and ozone depletion, and are perceived to be carcinogenic.
ICSH recommendations for identification, diagnostic value, and quantitation of schistocytes
Authors: ZINI G. , d’ONOFRIO G. , BRIGGS C. , ERBER W. , JOU J. M. , LEE S. H. , McFADDEN S. , VIVES‐CORRONS J. L. , YUTAKA N. , LESESVE J. F. 
Published: November 2011

SummarySchistocytes are fragments of red blood cells (RBCs) produced by extrinsic mechanical damage within the circulation. The detection of schistocytes is an important morphological clue to the diagnosis of thrombotic microangiopathic anemia (TMA). Reporting criteria between different laboratories, however, are not uniform, owing to variability of shape and nature of fragments, as well as subjectivity and heterogeneity in their morphological assessment. Lack of standardization may lead to inconsistency or misdiagnosis, thereby affecting treatment and clinical outcome. The Schistocyte Working Group of the International Council for Standardization in Haematology (ICSH) has prepared specific recommendations to standardize schistocyte identification, enumeration, and reporting. They deal with the type of smear, method of counting, morphological description based on positive criteria (helmet cells, small, irregular triangular, or crescent‐shaped cells, pointed projections, and lack of central pallor). A schistocyte count has a definite clinical value for the diagnosis of TMA in the absence of additional severe red cell shape abnormalities, with a confident threshold value of 1%. Automated counting of RBC fragments is also recommended by the ICSH Working Group as a useful complement to the microscope, according to the high predictive value of negative results, but worthy of further research and with limits in quantitation.
Novel Therapy with Intravesical Liposomes for Ulcerative Interstitial Cystitis/Painful Bladder Syndrome
Authors: PETERS Kenneth M. , HASENAU Deborah L. , ANTHONY Michele , KAUFMAN Jonathan , KILLINGER Kim A. 
Published: November 2011

Objectives: A Federal Drug Administration‐approved, compassionate‐use, investigational new drug single‐subject trial was conducted to evaluate the safety and clinical outcomes of intravesical instillation of liposomes in a woman with ulcerative interstitial cystitis/painful bladder syndrome (IC/PBS).Methods: After obtaining informed consent, the 48‐year‐old woman, diagnosed with ulcerative IC/PBS, received four weekly instillations of intravesical liposomes. Subsequently she was evaluated for 8 weeks post bladder instillation.Results: No side effects or adverse events were reported during the 12 week study period. Voids per day decreased from a baseline of 18 voids per 24 h to 11.3 voids per 24 h at week 3, and 12.6 voids per 24 h at 8 weeks after final instillation. Urgency score also decreased from a pre‐instillation mean of 1.75 (out of 10) to 1.07 8 weeks after the final instillation. Bladder ulcers noted by cystoscopy at baseline were absent at the 8 weeks post‐treatment and no evidence of bladder inflammation was noted.Conclusion: Intravesical liposome instillation is minimally invasive and presents an appealing new treatment for IC/PBS. Prospective trials are needed to assess intravesical liposomes for IC/PBS.
Selective breeding of mice for different susceptibilities to high fat diet‐induced glucose intolerance: Development of two novel mouse lines, Selectively bred Diet‐induced Glucose intolerance‐Prone and ‐Resistant
Authors: Nagao Mototsugu , Asai Akira , Kawahara Momoyo , Nakajima Yasushi , Sato Yuki , Tanimura Kyoko , Okajima Fumitaka , Takaya Makiyo , Sudo Mariko , Takemitsu Shuji , Harada Taro , Sugihara Hitoshi , Oikawa Shinichi 
Published: November 2011

AbstractAims/Introduction:  The development of type 2 diabetes is primarily due to lifestyle and environmental factors, as well as genetics, as shown by familial clustering. To establish mouse lines for evaluating heritable factors determining susceptibility to diet‐induced diabetes, we performed selective breeding for differences in high fat diet (HFD)‐induced glucose intolerance.Materials and Methods:  Selective breeding was performed using hybrid mice of C57BL/6J, C3H/HeJ and AKR/N backgrounds. After 5‐week HFD feeding, mice showing high and low 2‐h blood glucose levels in an oral glucose tolerance test (OGTT) were selected and bred over 14 generations to produce lines prone and resistant to diet‐induced glucose intolerance (designated Selectively bred Diet‐induced Glucose intolerance‐Prone [SDG‐P] and ‐Resistant [SDG‐R]).Results:  At 5 weeks of age (pre HFD feeding), SDG‐P mice showed higher blood glucose levels both in the OGTT and insulin tolerance test as compared to SDG‐R mice. After receiving HFD, the glucose intolerance of SDG‐P mice became more evident without hyper insulin secretion. In addition, SDG‐P mice had greater body weight gain and lower HDL‐cholesterol levels as compared to SDG‐R mice. In comparison with C57BL/6J, a well‐known strain prone to HFD‐induced glucose intolerance, SDG‐P mice showed significantly higher glucose levels in OGTT after the 5‐week HFD feeding.Conclusions:  Susceptibility to HFD‐induced glucose intolerance was transmitted over generations and was intensified by selective breeding. The newly established mouse lines, SDG‐P and SDG‐R, may be useful in investigating the pathophysiology of type 2 diabetes through elucidating the crucial factors for determining the susceptibility to HFD‐induced glucose intolerance. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2011.00175.x, 2011)
Oral piercings and their dental implications: a mini review
Authors: Singh Amrinder , Tuli Avantika 
Published: November 2011

AbstractOral piercing has become common in young adults in recent years. Adolescents are characterized by a compulsive tendency to distinguish themselves from the rest; differences in clothes, hairstyle, or “decorative” details are used to this effect, based on highly‐diverse criteria. Dental health‐care professionals need to be aware of the procedures and risks involved with oral piercings and the social and psychological reasons that lead people to engage in this practice, regardless of the risks. The present article addresses oral mutilation practices, specifically from the oral health perspective, as it is of concern to dental professionals due to the health risks and oral complications associated with such practices. The various oral ornaments, piercing sites, and their implications, orally, as well as systemically, have been discussed.
Complete Sequence of Broad-Host-Range Plasmid pRIO-5 Harboring the Extended-Spectrum-β-Lactamase Gene
bla
BES-1
Authors: Bonnin Rémy A. , Poirel Laurent , Sampaio Jorge Luiz Mello , Nordmann Patrice 
Published: November 2011

ABSTRACT

Broad-host-range plasmid pRIO-5, harboring the extended-spectrum β-lactamase
bla
BES-1
gene in
Serratia marcescens
, was fully sequenced. Analysis of the 12,957-bp sequence of this IncP6-type plasmid revealed that the
bla
BES-1
gene was associated with two copies of the insertion sequence IS
26
. The promoter responsible for the
bla
BES-1
expression was hybrid, made of a −35 box located inside the inverted repeat of IS
26
and a −10 box inside a remnant of an insertion sequence.
Prospective Investigation of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Community-Associated Methicillin-Resistant Staphylococcus aureus Infections
Authors: Miller Loren G. , Tan Jennifer , Eells Samantha J. , Benitez Esther , Radner Allen B. 
Published: November 2011

ABSTRACT

Recurrent community-associated methicillin-resistant
Staphylococcus aureus
(CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens. We prospectively evaluated 31 patients with recurrent CA-MRSA skin infections who received nasal mupirocin, topical hexachlorophene body wash, and an oral anti-MRSA antibiotic. The mean number of MRSA infections after the intervention decreased significantly from baseline (0.03 versus 0.84 infections/month,
P
= <0.0001). This regimen appears promising at preventing recurrent CA-MRSA infections.