bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidence in development of sustainability reporting: a case of a developing country
Authors: Amran Azlan , Haniffa Roszaini 
Published: February 2010

AbstractCurrent development in social accounting presents an interesting phenomenon. Companies are increasingly engaging in sustainability initiatives and reporting their activities in annual reports, company websites and other media of communication. Unlike previous studies, which have mainly used ex post content analysis of annual reports or other published data to study the relationship between disclosure and possible determinants, this study starts with an interview with the local preparer before the data is triangulated to determine the significant possible determinants. The interview findings are interpreted through institutional theory for possible identification of determinants. Initially, the interview findings indicate that all three mechanisms of isomorphism, the coercive, the normative and the mimetic, contribute to Malaysian company sustainability reporting. However, the regression results prove that only a government linked company in the plantation industry, which is large in size, has a significant amount of sustainability reporting. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Design and Synthesis of (13S)‐Methyl‐Substituted Arachidonic Acid Analogues: Templates for Novel Endocannabinoids
Authors: Papahatjis Demetris P. , Nahmias Victoria R. , Nikas Spyros P. , Schimpgen Marion , Makriyannis Alexandros 
Published: February 2010

AbstractTwo novel methyl‐substituted arachidonic acid derivatives were prepared in an enantioselective manner from commercially available chiral building blocks, and were found to be excellent templates for the development of (13S)‐methyl‐substituted anandamide analogues. One of the compounds synthesized, namely, (13S,5Z,8Z,11Z,14Z)‐13‐methyl‐eicosa‐5,8,11,14‐tetraenoic acidN‐(2‐hydroxyethyl)amide, is an endocannabinoid analogue with remarkably high affinity for the CB1 cannabinoid receptor.
Microwave Irradiation for the Facile Synthesis of Transition‐Metal Nanoparticles (NPs) in Ionic Liquids (ILs) from Metal–Carbonyl Precursors and Ru‐, Rh‐, and Ir‐NP/IL Dispersions as Biphasic Liquid–Liquid Hydrogenation Nanocatalysts for Cyclohexene
Authors: Vollmer Christian , Redel Engelbert , Abu‐Shandi Khalid , Thomann Ralf , Manyar Haresh , Hardacre Christopher , Janiak Christoph 
Published: February 2010

AbstractStable chromium, molybdenum, tungsten, manganese, rhenium, ruthenium, osmium, cobalt, rhodium, and iridium metal nanoparticles (M‐NPs) have been reproducibly obtained by facile, rapid (3 min), and energy‐saving 10 W microwave irradiation (MWI) under an argon atmosphere from their metal–carbonyl precursors [Mx(CO)y] in the ionic liquid (IL) 1‐butyl‐3‐methylimidazolium tetrafluoroborate ([BMIm][BF4]). This MWI synthesis is compared to UV‐photolytic (1000 W, 15 min) or conventional thermal decomposition (180–250 °C, 6–12 h) of [Mx(CO)y] in ILs. The MWI‐obtained nanoparticles have a very small (<5 nm) and uniform size and are prepared without any additional stabilizers or capping molecules as long‐term stable M‐NP/IL dispersions (characterization by transmission electron microscopy (TEM), transmission electron diffraction (TED), and dynamic light scattering (DLS)). The ruthenium, rhodium, or iridium nanoparticle/IL dispersions are highly active and easily recyclable catalysts for the biphasic liquid–liquid hydrogenation of cyclohexene to cyclohexane with activities of up to 522 (mol product) (mol Ru)−1 h−1 and 884 (mol product) (mol Rh)−1 h−1 and give almost quantitative conversion within 2 h at 10 bar H2 and 90 °C. Catalyst poisoning experiments with CS2 (0.05 equiv per Ru) suggest a heterogeneous surface catalysis of Ru‐NPs.
A mathematical method for the 3D analysis of rotating deformable systems applied on lumen‐forming MDCK cell aggregates
Authors: Marmaras Anastasios , Berge Ulrich , Ferrari Aldo , Kurtcuoglu Vartan , Poulikakos Dimos , Kroschewski Ruth 
Published: February 2010

AbstractCell motility contributes to the formation of organs and tissues, into which multiple cells self‐organize. However such mammalian cellular motilities are not characterized in a quantitative manner and the systemic consequences are thus unknown. A mathematical tool to decipher cell motility, accounting for changes in cell shape, within a three‐dimensional (3D) cell system was missing. We report here such a tool, usable on segmented images reporting the outline of clusters (cells) and allowing the time‐resolved 3D analysis of circular motility of these as parts of a system (cell aggregate). Our method can analyze circular motility in sub‐cellular, cellular, multi‐cellular, and also non‐cellular systems for which time‐resolved segmented cluster outlines are available. To exemplify, we characterized the circular motility of lumen‐initiating MDCK cell aggregates, embedded in extracellular matrix. We show that the organization of the major surrounding matrix fibers was not significantly affected during this cohort rotation. Using our developed tool, we discovered two classes of circular motion, rotation and random walk, organized in three behavior patterns during lumen initiation. As rotational movements were more rapid than random walk and as both could continue during lumen initiation, we conclude that neither the class nor the rate of motion regulates lumen initiation. We thus reveal a high degree of plasticity during a developmentally critical cell polarization step, indicating that lumen initiation is a robust process. However, motility rates decreased with increasing cell number, previously shown to correlate with epithelial polarization, suggesting that migratory polarization is converted into epithelial polarization during aggregate development. © 2010 Wiley‐Liss, Inc.
hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer
Authors: Gee Harriet E. , Camps Carme , Buffa Francesca M. , Patiar Shalini , Winter Stuart C. , Betts Guy , Homer Jarrod , Corbridge Rogan , Cox Graham , West Catharine M. L. , Ragoussis Jiannis , Harris Adrian L. 
Published: February 2010

AbstractBACKGROUND:Hypoxia is an important mechanism of treatment resistance in head and neck squamous cell carcinoma (HNSCC). MicroRNAs are short noncoding RNAs that regulate multiple mRNAs and are frequently dysregulated in cancer. The authors have investigated the role of 3 microRNAs, including the hypoxia‐induced hsa‐miR‐210, as potential markers of hypoxia or prognosis.METHODS:Three hypoxia‐related microRNAs, hsa‐miR‐210, hsa‐miR‐21, and hsa‐miR‐10b, were measured in 46 samples from patients with HNSCC. Expression levels were correlated with clinicopathological variables and other markers of hypoxia: a published 99‐gene hypoxia metagene, individual hypoxia‐related genes such as TWIST1, and immunohistochemical expression of hypoxia‐inducible factor 1 and its target gene carbonic anhydrase 9. We then performed survival analyses to investigate the prognostic significance of these microRNAs.RESULTS:Only the level of hsa‐miR‐210 was significantly correlated with other markers of hypoxia, including the 99‐gene hypoxia metagene (rho = 0.67, P < .001). We found no association between hsa‐miR‐210, hsa‐miR‐21, or hsa‐miR‐10b and clinicopathological variables such as tumor size, differentiation, and stage. However, high levels of hsa‐miR‐210 were associated with locoregional disease recurrence (P = .001) and short overall survival (P = .008). hsa‐miR‐21 and hsa‐miR‐10b had no prognostic significance.CONCLUSIONS:Expression of hsa‐miR‐210 in head and neck cancer correlates with other approaches for assessing hypoxia and is associated with prognosis. This warrants further study as a classification marker of patients for therapies involving modulation of hypoxia. Cancer 2010. © 2010 American Cancer Society.
Changes in markers of ovarian reserve and endocrine function in young women with breast cancer undergoing adjuvant chemotherapy
Authors: Yu Bo , Douglas Nataki , Ferin Michel J. , Nakhuda Gary S. , Crew Katherine , Lobo Rogerio A. , Hershman Dawn L. 
Published: February 2010

AbstractBACKGROUND:Premenopausal women undergoing chemotherapy are at risk for amenorrhea and impaired fertility. The objective of the current study was to assess levels of mullerian inhibitory substance (MIS), estradiol (E2), follicle‐stimulating hormone (FSH), and menstrual status, in women undergoing chemotherapy.METHODS:A nested prospective cohort study was conducted in women aged <40 years with breast cancer (BC) who were undergoing adjuvant chemotherapy (n = 26). Serum MIS, FSH, and E2 were measured before chemotherapy (baseline) and at Weeks 6, 12, 36, and 52. Controls were 134 age‐matched women with known fertility. Hormone levels were compared between the cases and controls at baseline. Differences between amenorrhea and age subgroups were tested using the nonparametric Wilcoxon 2‐sample test using a 2‐sided α of 0.05.RESULTS:Subjects with BC and age‐matched controls had similar baseline MIS levels (median, 0.94 ng/mL vs 0.86 ng/mL;, P > .05). Serum MIS decreased significantly at 6 weeks and remained suppressed for 52 weeks. E2 levels decreased, and FSH levels increased during chemotherapy; however, at 52 weeks, the levels returned to baseline. At 52 weeks, only 1 patient had MIS above the lower normal range, 15 had return of menstrual function, 11 had premenopausal levels of FSH, and 13 had follicular phase levels of E2. In women aged <35 years, 25% remained amenorrheic, whereas in women aged >35 years, 50% were amenorrheic. Amenorrheic and menstruating women were found to have similar MIS values at baseline and follow‐up.CONCLUSIONS:In young women with BC, chemotherapy decreases MIS rapidly and dramatically. Rapid reductions in MIS do not appear to be predictive of subsequent menstrual function. Ovarian reserve and endocrine function may be affected differently by chemotherapy. Cancer 2010. © 2010 American Cancer Society.
Heteroepitaxial Si/ZnO Hierarchical Nanostructures for Future Optoelectronic Devices
Authors: Devika Mudusu , Koteeswara Reddy Nandanapalli , Pevzner Alexander , Patolsky Fernando 
Published: February 2010

AbstractThe synthesis of highly‐ordered ultra‐dense heteroepitaxial Si/ZnO hierarchical nanostructures by a simple and cost‐effective approach is demonstrated. We also show, based on the same approach, the synthesis of ZnO nanoparticle‐decorated Si nanowire cores and Si/ZnO conformal core‐shell hetero‐nanostructures. The as‐synthesized ZnO nanobranches on Si nanowire cores exhibit an epitaxial relationship as (111)Si/(100) ZnO. Excellent control over the composition, dimensions, and density of ZnO branches on Si cores has been achieved. Thus, in future, this family of well‐controlled, high‐quality Si/ZnO hierarchical hetero‐nanostructures could play a role as multifunctional candidates in the fabrication of optoelectronic devices, particularly for the development of a new generation of solar‐cell devices.
Fine‐needle aspiration of metastatic radiation‐induced cutaneous epithelioid angiosarcoma of the breast to the liver: A diagnostic dilemma
Authors: Park Ji‐Weon , Serafica‐Karen Chantal , Das Kasturi 
Published: February 2010

AbstractRadiation therapy is a significant risk factor for the development of angiosarcoma. With the increase in breast conservation treatment, the incidence of cutaneous radiation‐induced angiosarcoma of the breast is rising. If the angiosarcoma demonstrates epithelioid features, the tumor cells may present a diagnostic dilemma on fine‐needle aspiration cytology. We present a case of metastatic radiation‐induced cutaneous epithelioid angiosarcoma of the breast to the liver and a review of the literature. Diagn. Cytopathol. 2010;38:768–771. © 2010 Wiley‐Liss, Inc.
In‐situ Study of the Solid‐Gas Reaction of BiCl3 to BiOCl via the Intermediate Hydrate BiCl3·H2O
Authors: Wosylus Aron , Hoffmann Stefan , Schmidt Marcus , Ruck Michael 
Published: February 2010

AbstractAt ambient conditions the hydrolysis of BiCl3 to BiOCl proceeds via the intermediate hydrate BiCl3·H2O as has been revealed by time dependent in‐situ X‐ray powder diffraction as well as time and temperature controlled TG‐MS experiments. Below 50 °C the topochemical formation of thehydrate can be reversed by reducing the H2O vapour pressure. Above this temperature the hydrate is unstable and the mechanism of the hydrolysis changes. BiCl3·H2O crystallizes in the monoclinic space group C2/m with lattice parameters a = 1114.25(1) pm, b = 876.82(1) pm, c = 584.20(1) pm, and β = 106.64(1)°.
Lewis Acid Activated Aza‐Diels–Alder Reaction of N‐(3‐Pyridyl)aldimines: An Experimental and Computational Study
Authors: Palacios Francisco , Alonso Concepción , Arrieta Ana , Cossío Fernando P. , Ezpeleta Jose M. , Fuertes María , Rubiales Gloria 
Published: February 2010

AbstractA combined theoretical and experimental study of a Povarov‐type cycloaddition reaction suggests an asynchronous concerted process that is favored by double Lewis acid activation with BF3·Et2O; endo selectivity was observed in the reactions between N‐(3‐pyridyl)aldimines and styrene, cyclopentadiene, or indene, and substituted tetrahydro‐1,5‐naphthyridine derivatives were obtained in a regio‐ and stereoselective fashion.
Investigation on inorganic oxidant assisted sonocatalytic degradation of acid red B in the presence of nano‐sized TiO2 powder
Authors: Wang Jun , Lv Yanhui , Zhang Liqun , Jiang Renzheng , Han Guangxi , Liu Bin , Wang Dan , Zhang Xiangdong 
Published: February 2010

AbstractIn this work, the effective degradation of Acid Red B dyes in aqueous solution was realized in various ultrasound (US)/TiO2/oxidant (KIO4, KIO3 and K2S2O8) systems. In addition, the degradation efficiencies of Acid Red B in US/TiO2/oxidant systems for a variety of oxidants were compared. The results revealed the obvious synergistic effects of sonocatalytic technology (ultrasonic irradiation combined with TiO2) and oxidants (KIO4, KIO3, and K2S2O8). Simultaneously, the effects of some operational parameters such as oxidant kind, ultrasonic irradiation time, solution acidity, oxidant concentration, and system temperature on the sonocatalytic degradation of Acid Red B have also been examined in this article. Under the same conditions, the degradation efficiency of Acid Red B dye was found to retain the order of US/TiO2/KIO4 > US/TiO2/K2S2O8 > US/TiO2/KIO3 > US/TiO2 > US. Particularly, by using US/TiO2/KIO4 system this method can remarkably shorten the degradation reaction time and completely degraded the Acid Red B. The method of sonocatalytic degradation assisted with oxidants exhibits a widely applied foreground, therefore, should be a feasible choice for treating various organic wastewaters, especially, non‐ or low‐transparent dye wastewaters. © 2010 American Institute of Chemical Engineers Environ Prog, 2010
Modeling mercury biomagnification (South River, Virginia, USA) to inform river management decision making
Authors: Tom Kyle R. , Newman Michael C. , Schmerfeld John 
Published: February 2010

AbstractMercury trophic transfer in the South River (VA, USA) was modeled to guide river remediation decision making. Sixteen different biota types were collected at six sites within 23 river miles. Mercury biomagnification was modeled using a general biomagnification model based on δ15N and distance from the historic mercury release. Methylmercury trophic transfer was clearer than that for total Hg and, therefore, was used to build the predictive model (r2 prediction = 0.76). The methylmercury biomagnification factors were similar among sites, but model intercept did increase with distance down river. Minimum Akaike's Information Criterion Estimation (MAICE) justified the incorporation of distance in the model. A model with a very similar biomagnification factor to the South River (95% confidence intervals [CI] = 0.38–0.52) was produced for a second contaminated Virginia river, the North Fork Holston River (95% CI = 0.41–0.55). Percent of total Hg that was methylmercury increased monotonically with trophic position. Trophic models based on δ15N were adequate for predicting changes in mercury concentrations in edible fish under different remediation scenarios. Environ. Toxicol. Chem. 2010;29:1013–1020. © 2010 SETAC
Tissue-specific distribution and whole-body burden estimates of persistent organic pollutants in the bottlenose dolphin (Tursiops truncatus)
Authors: Yordy Jennifer E. , Pabst D. Ann , McLellan William A. , Wells Randall S. , Rowles Teri K. , Kucklick John R. 
Published: February 2010

Abstract
Most exposure assessments for free-ranging cetaceans focus on contaminant concentrations measured in blubber, and few data are available for other tissues or the factors governing contaminant distribution among tissues. The goal of this study was to provide a detailed description of the distribution of persistent organic pollutants (POPs) within the common bottlenose dolphin (Tursiops truncatus) body and assess the role of lipid dynamics in mediating contaminant distribution. Thirteen tissues (brain, blubber, heart, liver, lung, kidney, mammary gland, melon, skeletal muscle, spleen, thyroid, thymus, and testis/uterus) were sampled during necropsy from bottlenose dolphins (n = 4) and analyzed for lipid and 85 POPs, including polychlorinated biphenyls, organochlorine pesticides, and polybrominated diphenyl ethers. Significant correlations between tissue POP concentrations and lipid suggest that distribution of POPs is generally related to tissue lipid content. However, blubber:tissue partition coefficients ranged widely from 0.753 to 6.25, suggesting that contaminant distribution is not entirely lipid-dependent. Tissue-specific and whole-body contaminant burdens confirmed that blubber, the primary site of metabolic lipid storage, is also the primary site for POP accumulation, contributing &gt;90% to the whole-body burdens. Observations also suggest that as lipid mobilizes from blubber, contaminants may redistribute, leading to elevated tissue concentrations. These results suggest that individuals with reduced blubber lipid may be at increased risk for exposure-related health effects. However, this study also provides evidence that the melon, a metabolically inert lipid-rich structure, may serve as an alternate depot for POPs, thus preventing the bulk of blubber contaminants from being directly available to other tissues. This unique physiological adaptation should be taken into consideration when assessing contaminant-related health effects in wild cetacean populations. Environ. Toxicol. Chem. 2010;29:1263–1273. © 2010 SETAC
Occurrence and a screening-level risk assessment of human pharmaceuticals in the Pearl River system, South China
Authors: Zhao Jian-Liang , Ying Guang-Guo , Liu You-Sheng , Chen Feng , Yang Ji-Feng , Wang Li , Yang Xiao-Bing , Stauber Jenny L. , Warne Michael St. J. 
Published: February 2010

Abstract
Ten nonsteroidal antiinflammatory drugs (NSAIDs), two blood lipid regulators (BLRs), and two antiepileptic drugs (AEDs) were analyzed in the Pearl River system in China (i.e., Liuxi, Zhujiang, and Shijing Rivers) and four sewage effluents during the dry and wet seasons, and the environmental risks they posed were assessed. Eight pharmaceuticals were detected in the rivers and effluents, including five NSAIDs (salicylic acid, ibuprofen, diclofenac, mefenamic acid, and naproxen), two BLRs (clofibric acid and gemfibrozil), and one AED (carbamazepine). The median concentrations for the eight pharmaceuticals ranged from 11.2 to 102 ng/L. Seasonal variations were not obvious for most pharmaceuticals in the three rivers, except for salicylic acid and clofibric acid in the Zhujiang River, and diclofenac in the Zhujiang and Shijing Rivers. However, spatially considerable variations in the concentrations were observed for the eight pharmaceuticals in all three rivers. For most of the pharmaceuticals, the effluents from the four wastewater treatment plants and Shijing River water were found to be the major discharge sources for the Zhujiang River, but with additional discharge sources from some small urban streams in the wet season. Diclofenac in the Shijing River was the only pharmaceutical that had a risk quotient (RQ) &gt;1, indicating a high risk to aquatic organisms in the river. Although higher RQs were calculated for the mixture of the pharmaceuticals in each river, the risk rating remained the same for the three rivers with the RQ being &gt;1 only in Shijing River. Environ. Toxicol. Chem. 2010;29:1377–1384. © 2010 SETAC
A new simple square root option pricing model
Authors: Câmara António , Wang Yaw‐huei 
Published: February 2010

AbstractThis study derives a simple square root option pricing model using a general equilibrium approach in an economy where the representative agent has a generalized logarithmic utility function. Our option pricing formulae, like the Black–Scholes model, do not depend on the preference parameters of the utility function of the representative agent. Although the Black–Scholes model introduces limited liability in asset prices by assuming that the logarithm of the stock price has a normal distribution, our basic square root option pricing model introduces limited liability by assuming that the square root of the stock price has a normal distribution. The empirical tests on the S&P 500 index options market show that our model has smaller fitting errors than the Black–Scholes model, and that it generates volatility skews with similar shapes to those observed in the marketplace. © 2010 Wiley Periodicals, Inc. Jrl Fut Mark
Intraoperative evaluation of bony margins with frozen‐section analysis and trephine drill extraction technique: A preliminary study
Authors: Wysluch Andreas , Stricker Ingo , Hölzle Frank , Wolff Klaus‐Dietrich , Maurer Peter 
Published: February 2010

AbstractBackgroundThe aim of this study was to examine the use of trephine drill specimens from mandible bony margins subjected to standard histologic fresh‐frozen processing for intraoperative documentation of malignant bony infiltration in oral cancer.MethodsEighty‐four drill specimens were extracted from bony mandibular resection margins of 20 patients with oral cancer. Histologic results of decalcification and of intraoperative frozen‐section analysis were compared.ResultsSixty‐eight (81%) of 84 specimens showed no tumor infiltration, whereas 16 (19%) were positive in frozen section analysis. Four specimens (4.8%) were evaluated as free of tumor invasion, but showed erosion of the bone by the tumor after decalcification. One specimen (2.4%) was positive, but no invasion could be found with standard decalcification. Overall, there was 94% (79) consistency between the 2 techniques, with a sensitivity of 79% and specificity of 98%.ConclusionThis technique promises to be suitable for intraoperative detection of malignant bone infiltration. © 2010 Wiley Periodicals, Inc. Head Neck, 2010
Understanding oral cancer in the genome era
Authors: Viet Chi T. , Schmidt Brian L. 
Published: February 2010

AbstractCompletion of the human genome project approximately 15 years ago was followed closely by advancements in array technology. Investigators quickly applied this new powerful tool to the genomic and proteomic study of oral squamous cell carcinoma (OSCC). Resultant publications documented chromosome, gene, mRNA, and protein alterations that characterize oral cancer. In this review, we summarize how the genomic, proteomic, and epigenetic array studies have provided insight into the process of oral carcinogenesis. We discuss the significant limitations and requirement for validation of these array studies. We also review the manner in which state‐of‐the‐art, high‐throughput approaches are being used to search for salivary and serum oral cancer biomarkers. © 2010 Wiley Periodicals, Inc. Head Neck, 2010