bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic review and network meta-analysis on the efficacy and safety of parmacotherapy for hand osteoarthritis
Authors: Wu Ruiqi , Peng Qinglin , Wang Weiwei , Zheng Jixian , Zhou Yi , Yang Qipei , Zhang Xuan , Li Hongyu , Meng Lin 
Published: May 2024

Objective
Hand osteoarthritis poses a significant health challenge globally due to its increasing prevalence and the substantial burden on individuals and the society. In current clinical practice, treatment options for hand osteoarthritis encompass a range of approaches, including biological agents, antimetabolic drugs, neuromuscular blockers, anti-inflammatory drugs, hormone medications, pain relievers, new synergistic drugs, and other medications. Despite the diverse array of treatments, determining the optimal regimen remains elusive. This study seeks to conduct a network meta-analysis to assess the effectiveness and safety of various drug intervention measures in the treatment of hand osteoarthritis. The findings aim to provide evidence-based support for the clinical management of hand osteoarthritis.

Methods
We performed a comprehensive search across PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials was conducted until September 15th, 2022, to identify relevant randomized controlled trials. After meticulous screening and data extraction, the Cochrane Handbook’s risk of bias assessment tool was applied to evaluate study quality. Data synthesis was carried out using Stata 15.1 software.

Results
21 studies with data for 3965 patients were meta-analyzed, involving 20 distinct Western medicine agents. GCSB-5, a specific herbal complex that mainly regulate pain in hand osteoarthritis, showed the greatest reduction in pain [WMD = -13.00, 95% CI (-26.69, 0.69)]. CRx-102, s specific medication characterized by its significant effect for relieving joint stiffness symptoms, remarkably mitigated stiffness [WMD = -7.50, 95% CI (-8.90, -6.10)]. Chondroitin sulfate displayed the highest incidence of adverse events [RR = 0.26, 95% CI (0.06, 1.22)]. No substantial variation in functional index for hand osteoarthritis score improvement was identified between distinct agents and placebo.

Conclusions
In summary, GCSB-5 and CRx-102 exhibit efficacy in alleviating pain and stiffness in HOA, respectively. However, cautious interpretation of the results is advised. Tailored treatment decisions based on individual contexts are imperative.
Characteristics of consecutive versus non-consecutive frequent emergency medical services transport to a single emergency department
Authors: Kim Sun Hyu , Lee Hyeji 
Published: May 2024

Objective
This study was to examine characteristics concerning frequent users of emergency medical services (EMS) transport by comparing patients who used EMS transport frequently for one year and those who used EMS transport for more than two years consecutively.

Methods
A retrospective review for frequent use of EMS transport was conducted. The patients from the fire stations that transported more than 70% of all EMS transport to the study hospital emergency department (ED) were included. The study subjects were divided into consecutive group (frequent EMS transport for ≥ two years consecutively) and non-consecutive group (frequent EMS transport for only one year). Characteristics of patients who were frequent users of EMS transport and those of all cases with EMS transport were examined.

Results
Of the total 205 patients and 1204 cases of frequent EMS transport, 85 (42%) patients and 755 (63%) cases were in the consecutive group. Patients in the consecutive group were more likely to have risky alcohol use, unemployed state, and medical aid type of payment for ED treatment than those in the non-consecutive group. More patients had previous experience of EMS transport to the study hospital ED in the consecutive group and the number of cases with alcohol ingestion was higher in the consecutive group. Elapsed time from EMS call to ED arrival was longer for the consecutive group.

Conclusion
Risky alcohol use, unemployed state, and previous experience of EMS transport were associated with consecutive and frequent use of EMS transport in frequent users of EMS transport.
Smoking is associated with higher risk of contracting bacterial infection and pneumonia, intensive care unit admission and death
Authors: Stattin Karl , Eriksson Mikael , Frithiof Robert , Kawati Rafael , Crockett Douglas , Hultström Michael , Lipcsey Miklos 
Published: May 2024

Background
Smoking has been associated with a higher risk of contracting pneumonia, but contradictory results have shown that smoking may or may not decrease the risk of dying in pneumonia. The aim of this study is to investigate how smoking is associated with contracting any infection and pneumonia and death.

Method and findings
Participants were drawn from the population-based Cohort of Swedish Men and the Swedish Mammography Cohort, which are representative of the Swedish population. Participants have answered detailed lifestyle questionnaires and have been followed in national registers, such as the Patient Register, Cause of Death register and Swedish Intensive Care Registry. The risks of contracting infection and pneumonia or dying in infection and pneumonia were assessed using Cox regression. Of 62,902 cohort participants, 25,297 contracted an infection of which 4,505 died; and 10,471 contracted pneumonia of which 2,851 died. Compared to never smokers, former smokers at baseline had hazard ratio (HR) 1.08 (95% confidence interval (CI) 1.05–1.12) of contracting and HR 1.19 (95% CI 1.11–1.28) of dying in infection and HR 1.17 (95% CI 1.12–1.23) of contracting and HR 1.16 (95% CI 1.06–1.27) of dying in pneumonia during follow-up. Compared to never smokers, current smokers at baseline had HR 1.17 (95% CI 1.13–1.21) of contracting infection and HR 1.64 (95% CI 1.52–1.77) dying in infection; HR 1.42 (95% CI 1.35–1.49) of contracting pneumonia and HR 1.70 (95% CI 1.55–1.87) of dying in pneumonia during follow-up. The risk of contracting and dying in infection and pneumonia increased in a dose-response manner with number of pack years smoked and decreased with years since smoking cessation.

Conclusion
Smoking is associated with contracting and dying in any infection and pneumonia and the risk increases with pack years smoked, highlighting the importance of both primary prevention and smoking cessation.
Patterns of eating behaviors, physical activity, and lifestyle modifications among Bangladeshi adolescents during the COVID-19 pandemic
Authors: Ferdous Most. Zannatul , Islam Md. Saiful , Kundu Lakshmi Rani , Islam Ummay Soumayia , Banik Rajon , Pardhan Shahina 
Published: May 2024

Background
Several safety measures like movement restrictions, closure of educational institutions, and social distancing measures continue over the world including Bangladesh during the COVID-19 pandemic. This study aimed to examine the patterns of eating behaviors, physical activity, and lifestyle modifications among adolescents during the COVID-19 pandemic residing in Bangladesh.

Methods
A cross-sectional study was performed among 490 adolescents in Bangladesh from December 2020 to May 2021. The survey was carried out through a semi-structured web-based questionnaire that asked questions about socio-demographics (i.e., age, sex, marital status, education, residence), perceived health status and quality of life, anthropometrics (i.e., height, weight), dietary habits (i.e., frequency of eating, daily intake of certain foods, number of meals eaten daily), and physical activity (i.e., modified version of the International Physical Activity Questionnaire Short Form [IPAQ-SF]), as well as, pre- and during COVID-19 information on stress, and sleep.

Results
During the pandemic, 43.7% participants reported weight gain; and 23.5% reported an increased number of meals per day during COVID-19. Additionally, the participants’ eating habits diverged from the local balanced diet principles and were more akin to ‘unhealthy’ eating patterns. Though, during the COVID-19 pandemic, physical exercise slightly increased (>3 times/ week: 8.2% vs. 13.5%; p<0.001) compared to pre-COVID-19 period, the screen time for entertainment increased drastically (>5 hours/ week: 12.2% vs. 27.3%; p<0.001). Compared to the pre-pandemic, a sizeable proportion of individuals experienced more physical tiredness, emotional exhaustion, irritation, and stress (p<0.001) during the pandemic. During the pandemic, 47.5% of participants experienced different sleep difficulties.

Conclusions
Although lockdowns and social distancing are important safety measures to protect people from COVID-19, findings reveal that they might cause a variety of lifestyle changes, physical inactivity, and psychological issues in Bangladeshi adolescents.
Frailty and transplant-free survival of patients with liver cirrhosis: A meta-analysis
Authors: Yuan Chunhui , Li Weihua , Liu Jie , Li Jianguo 
Published: May 2024

Background
Frailty is a common condition among patients with liver cirrhosis. Nonetheless, its role in predicting liver transplant-free survival (TFS) remains unclear.

Aim
This systematic review and meta-analysis were conducted to elucidate the relationship between frailty and TFS in patients with cirrhosis.

Methods
Cohort studies addressing the objective of this meta-analysis were extracted from PubMed, Embase, and Web of Science databases. Between-study heterogeneity was assessed with the Cochrane Q test, and the I^2 statistic was estimated. Random-effect models, considering potential heterogeneity, were employed to combine the results.

Results
The meta-analysis encompassed 17 cohort studies involving 6273 patients with cirrhosis, of whom 1983 (31.6%) were classified as frail at baseline. The follow-up periods in the included studies ranged from 3 to 29 months, with an average duration of 11.5 months. The analysis revealed that frailty was significantly associated with a poor TFS (risk ratio [RR]: 2.07, 95% confidence interval: 1.72 to 2.50, p<0.001; I2 = 51%). Sensitivity analyses that sequentially omitted one dataset consistently supported these findings (RR: 1.95 to 2.17, p<0.05 in all cases). Subgroup analyses based on variables such as study design, mean age of patients, baseline Model for End-Stage Liver Disease score, tool used for frailty evaluation, follow-up duration, and study quality score also yielded congruent results.

Conclusions
The evidence suggests that frailty may be an independent risk factor for poor TFS in patients with liver cirrhosis, thus emphasizing the importance of early identification and management of frailty in this population.
Predictors of positive tuberculin skin test in neonates exposed to pulmonary tuberculosis
Authors: Choi Yun , Kim In Kyoung , Kim So Jung , Kim Hye Sung , Kang Young Ae , Song Jin Su 
Published: May 2024

Background
Neonates are at risk of nosocomial tuberculosis (TB) infection from health care workers (HCWs) in neonatal care facilities, which can progress to severe TB diseases. Tuberculin skin test (TST) is commonly used for TB diagnosis, but its accuracy in neonates is influenced by various factors, including bacilli Calmette-Guérin (BCG) vaccination. This study aimed to identify predictors of positive TSTs in neonates exposed to HCWs with pulmonary TB.

Methods
A retrospective observational study was conducted to compare the frequency of predictors between TST-positive and TST-negative neonates. Demographic, epidemiological, and clinical data of neonates exposed to TB, along with that of HCW and household contacts, were collected retrospectively through contact investigations with the Korean National TB Surveillance System (KNTSS) database. TSTs using 2 tuberculin units of purified protein derivative RT23 were performed on exposed neonates at the end of preventive TB treatment. Firth logistic regression was performed to identify predictors of TST positivity.

Results
Contact investigations revealed that 152 neonates and 54 HCWs were exposed to infectious TB index cases in 3 neonatal care facilities. Of 152 exposed neonates, 8 (5.3%) had positive TST results. Age of 6 days or more at the initial exposure is a statistically significant predictor of positive TST (Firth coefficient 2.1, 95% confidence interval 0.3–3.9, P = 0.024); BCG vaccination showed no statistical significance in both univariable and multivariable analysis. Sex, prematurity, exposure duration, duration from initial exposure to contact investigation, and isoniazid preventive treatment duration were not significant predictors.

Conclusion
Age at the initial exposure is a significant predictor of positive TST in neonates exposed to active pulmonary TB. Given the complexities of TST interpretation, including false positives due to BCG vaccination, careful risk assessment is necessary for appropriate decision-making and resource allocation in the management of neonatal TB exposure.
Predictors of renal function deterioration at one year after off-clamp non-renorrhaphy partial nephrectomy
Authors: Nakamura Masaki , Kameyama Shuji , Tsuru Ibuki , Izumi Taro , Ono Akihiro , Teshima Taro , Inoue Yasushi , Amakawa Ryo , Inatsu Hiroki , Yoshimatsu Tadashi , Kusakabe Masashi , Morikawa Teppei , Shiga Yoshiyuki 
Published: May 2024

Background
Preservation of renal function is an important goal in renal cell carcinoma-related surgery. Although several case-dependent techniques for renal pedicle clamping and hemostasis have been used, their effects on long-term renal function are controversial.

Methods
The clinical records of 114 patients who underwent off-clamp non-renorrhaphy open partial nephrectomy at our hospital were retrospectively reviewed. Perioperative estimated glomerular filtration rate (eGFR) preservation was calculated, and predictors of eGFR decline 12 months post-surgery and overtime deterioration of renal function were identified using a multivariate regression analysis.

Results
The median patient age was 65 years, and the median tumor size was 27 mm. The mean eGFR preservation at 1, 3, and 12 months post-surgery were 90.1%, 89.0%, and 86.9%, respectively. eGFR decline at 1 and 3 months were associated with poor eGFR preservation at 12 months with the odds ratio (95% confidence interval (CI)) of 1.97 and 3.157, respectively. Multivariate regression analyses revealed that tumor size was an independent predictor of eGFR decline at 12 months. Among 65 patients with eGFR preservation over 90% at 1 month post-surgery, eGFR value of 28 patients deteriorated below 90% at 12 months post-surgery compared with preoperative eGFR. Tumor size and eGFR preservation at 1 month were independent predictors of long-term renal function deterioration.

Conclusion
Tumor size predicted eGFR decline 12 months post-surgery. Only a mild decline in eGFR was observed between 3 and 12 months after open partial nephrectomy. Tumor size and eGFR preservation at 1 month predicted the deterioration of renal function over time.
FAKTOR YANG BERHUBUNGAN DENGAN PRAKTIK PELAYANAN ANTENATAL CARE TERPADU PADA BIDAN DI PUSKESMAS COLOMADU
Authors: Cahyanti Anisa Nur , Mawarni Atik , Winarni Sri , Purnami Cahya Tri 
Published: May 2024

Visits of pregnant women during the Covid 19 pandemic at the Colomadu Health Center has decreased by 20%, visits before the pandemic could reach 100% and decreased to 80% during the pandemic. The decrease in visits was caused by the anxiety of pregnant women about the transmission of the virus and the unstandardized Integrated ANC (Antenatal care) services by the midwives. Midwives did not provide counseling, hand and foot examinations, and breast examinations. The purpose of this study is to analyze the relationship between age, knowledge, attitudes, and motivation with the practice of the Integrated ANC services for midwives at the Colomadu Health Center. This study was an observational study with a cross-sectional design. The research sample used a purposive sampling technique, namely 14 midwives. Data analysis uses Pearson correlation test. The result showed that age (p-value=0.006), knowledge (p-value=0.0001), attitude (p-value=0.004), and motivation (p-value=0.009) were related to the practice of the Integrated ANC services. The factor that has the highest correlation coefficient was knowledge (r=0.853). This study concludes that there is a significant relationship between age, knowledge, attitude, and motivation with the practice of the Integrated ANC services.
ANALYSIS OF TRAIN VIBRATION AND NOISE ON POPULATION SUBJECTIVE COMPLAINTS
Authors: Alfira Fitria Ade , Khambali Khambali , Suprijandani Suprijandani , Sari Ernita 
Published: May 2024

Passing trains causes vibration and noise, the Ministry of the environment monitors noise and vibration of trains getting results 100% exceeding the quality standards carried out in four big cities. This study aimed to determine the analysis of train vibration and noise on subjective complaints of residents of Bringinbendo Village. This type of research used descriptive research with a cross sectional approach. The population used was housewives who were in the Bringinbendo Village area, especially in RW 04 (RT 07, RT 09) and RW 07 (RT 10, RT 12) Taman District, Sidoarjo Regency as many as 132. The sample used was 99 housewives who taken by simple random sampling method. Data analysis was carried out descriptively to describe the data. The vibration measurement at point 1 is 2.1 Hz and at point 2 is 1 Hz, both points were still below the standard vibration level, while the noise measurement at point 1 is 75.95 dB(A) and at point 2 is 70.56 dB( A) the value exceeds the specified noise quality standard. Subjective complaints obtained from interviews were 63.6% had complaints and 36.4% had no complaints. The vibration and noise of the train can caused residents to experience subjective complaints. People should exercise control in their homes to reduce the noise of the train. Keywords: train, vibration, noise
The construction of sports tourism projects under the strategy of national fitness by wireless sensor network
Authors: Yuan Zhen 
Published: May 2024

Abstract
In recent years, sports events have continuously attracted people’s attention, and people’s enthusiasm and participation in sports have been rising. The sports + tourism model can meet people’s travel needs and enjoy sports-related entertainment and experiences. With the expansion of sports tourism, people have a new understanding of sports + tourism. Sports tourism based on the current strategic background of national fitness is an emerging industry, and it has had a certain degree of development prospects before this. This article explores traditional sports tourism with national characteristics under the blessing of the wireless sensor network. This exploration discusses and explores the development and construction of local sports + tourism in terms of literature and logical analysis. The experimental results of this article show that most consumers are not satisfied with the construction of sports tourism network information, and they are the least satisfied with key information coverage, e-commerce, and security systems. It shows that in these aspects, the construction of sports tourism informatization is relatively lagging, and it is in urgent need of improvement and improvement.
Motor imagery as a potential tool to alleviate choking under pressure in sports performance
Authors: Li Zhi , Moritz Sandra E. , Liu Hairui 
Published: May 2024

Abstract
Choking under pressure is a popular issue in sports, having adverse effects on athletes’ performance. It can occur for various reasons, such as debilitative anxiety, increased fear of failure, lack of confidence, lack of preparation, and the presence of distractions. This review investigates the utility of motor imagery as an intervention for choking. Motor imagery, a cognitive process encompassing mental rehearsal of physical movements without physical execution, has been demonstrated to enhance motor skill acquisition and execution among athletes. Beyond its efficacy in enhancing motor skills, motor imagery imparts psychological advantages to athletes by reducing anxiety and bolstering confidence, both pivotal factors in averting performance breakdowns under pressure. In summary, motor imagery holds promise as an intervention for alleviating choking under pressure in sports performance. Nonetheless, further investigations are imperative to ascertain optimal approaches for integrating motor imagery into sports training and competitive settings.
Synthesis of potash alum from waste aluminum cans for the purification of river water
Authors: Tetteh Samuel , Mahama Nuriya 
Published: May 2024

Abstract
This study explored the synthesis of potash alum from disposed aluminum cans for water purification. The effect of the labels on the cans on the yield of alum was also investigated as it is economically beneficial for industry. Single crystals of potash alum were obtained and characterized by powder X-ray diffraction (P-XRD) and Fourier transform infrared (FTIR) spectroscopy. Through a series of jar test experiments, the characterized alum samples were used to purify river water samples. Some of the parameters investigated include; pH, turbidity, total suspended solids (TSS), total dissolved solids (TDS), electrical conductivity (EC) and chemical oxygen demand (COD). The results show that the alum samples were able to reduce the turbidity by 100 % and substantially decrease the TSS, TDS and COD over the five-hour period of study. However, there were slight increases in acidity and EC which could be corrected by other methods
Experimental research on influence of curing environment on mechanical properties of coal gangue cementation
Authors: Wu Haifeng , Shen Jianjun , Liu Yin 
Published: May 2024

Abstract
To investigate the impact of curing environments on the mechanical properties of coal gangue cementation (CGC), various curing methods were established, including standard bag curing, standard curing, natural sealing curing, natural curing, water curing, and varying curing ages. By examining the uniaxial compressive strength (UCS) and stress–strain relationship of CGC by applying axial loads, the influence mechanism was analyzed in terms of both physical and chemical reactions. Furthermore, a mechanistic structural model was established to illustrate the impact of the curing environment on the mechanical properties of CGC. The primary substances and reasons affecting the mechanical properties of CGC were analyzed through the use of scanning electron microscopy and X-ray diffraction techniques. Evaluation of influence factors on CGC mechanical properties by grey correlation degree. The findings indicate that curing temperature, humidity, and carbonization are the principal factors influencing the UCS. Maintaining constant temperature and humidity while isolating CO2 is conducive to improving the UCS. The hydration products, such as needle-like ettringite and white fibrous calcium silicate hydrogel, fill the internal voids of CGC and are the primary substances affecting UCS. The hydration products formed during standard curing and natural curing of CGC can undergo carbonation with CO2 to form CaCO3, which interacts with ettringite and hydrated calcium silicate to provide strength support for CGC. However, beyond a certain age, CO2 will progressively diminish the UCS; the larger the contact area and the longer the exposure time to the gel materials in CGC, the faster the UCS decreases.