bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minorité et déloyauté : protection de l’équité de la procédure
Authors: Porret Arthur 
Published: June 2024

En vertu de l’article L. 12‑2 du Code de la justice pénale des mineurs, le magistrat du parquet requérant contre un mineur doit, à peine de nullité, être spécialement chargé des affaires concernant les mineurs.Le fait de dissimuler des éléments de preuve et de les camoufler par l’établissement d’un procès‑verbal de constatations visuelles constitue une atteinte au droit au procès équitable et au principe de liberté de la preuve qui justifie une annulation de la pièce et de toute la procédure subséquente.
Conciliation : date d’appréciation de la condition d’ouverture relative à la cessation des paiements
Authors: Zinty Stéphane 
Published: June 2024

La condition selon laquelle le débiteur ne doit pas être en cessation des paiements depuis plus de 45 jours afin de bénéficier de l’ouverture d’une conciliation s’apprécie à la date du dépôt de la requête.
How Assessment Choice Affects Student Perception and Performance
Authors: Unger Sanne , Lecher Alanna 
Published: June 2024

Abstract. This action research project examined the effect of student assessment choice on grades and course evaluations, the two assessment options being a reading quiz or a two-minute video recording of themselves recalling what they could about the text (a “recall”). In the baseline condition (year 1), students were encouraged to complete recall videos about reading assignments for a type of extra credit in addition to required multiple-choice reading quizzes. In the experimental year (year 2), students were instead allowed to replace reading quizzes with recalls. The data included student submissions, grades, and course evaluations. Students completed more recall assignments when the recall replaced the quiz requirement than during the baseline year when recalls could not replace quizzes. In addition, the instances of students completing both the quiz and recall (for extra credit) increased in the experimental year. Average course grades did not change from the baseline year to the experimental year, but students with higher course grades were significantly more likely to have completed recalls. Student evaluations of the instructor were significantly higher for “responses to diverse learning styles” in the experimental year compared to the baseline condition. The study shows that letting students choose the assessment type they prefer can lead to increased student engagement and improve their perception of the instructor’s responsiveness to learning styles, without causing grade inflation.
Two-point boundary-value problems for differential equations with generalized piecewise-constant argument
Authors: Assanova Anar T. , Uteshova Roza E. 
Published: June 2024

UDC 517.9 We consider a two-point boundary-value problem for a system of differential equations with generalized piecewise-constant argument. To solve the problem, we propose to use a constructive method based on the Dzhumabaev parametrization method and a new approach to the concept of general solution. The interval is partitioned with regard for the singularities of the argument. The values of the solution at the interior points of the partition are regarded as additional parameters, and the differential equation is transformed into a system of Cauchy problems with parameters on subintervals of the partition. By using the solutions of these problems, we obtain a new general solution of the differential equation with piecewise-constant argument and establish its properties. The new general solution, boundary conditions, and the conditions of continuity of the solution at the interior points of the partition are used to construct a linear system of algebraic equations for the introduced parameters. The coefficients and the right-hand side of the system are found as a result of the solution of Cauchy problems for linear ordinary differential equations on the subintervals of the partition. It is shown that the solvability of the boundary-value problem is equivalent to the solvability of the constructed system. We propose algorithms of the parametrization method for solving the analyzed boundary-value problem and establish necessary and sufficient conditions for the well-posedness of this problem.
Deciphering Radio Emissions from Accretion Disk Winds in Radio-quiet Active Galactic Nuclei
Authors: Yamada Tomoya , Sakai Nobuyuki , Inoue Yoshiyuki , Michiyama Tomonari 
Published: June 2024

Abstract
Unraveling the origins of radio emissions from radio-quiet active galactic nuclei (RQ AGNs) remains a pivotal challenge in astrophysics. One potential source of this radiation is the shock interaction between AGN disk winds and the interstellar medium (ISM). To understand this phenomenon, we construct a spherical, one-zone, and self-similar expansion model of shock structure between ultrafast outflows (UFOs) and the ISM. We then calculate the energy density distribution of nonthermal electrons by solving the transport equation, considering diffusive shock acceleration as the acceleration mechanism and synchrotron and inverse Compton cooling as the cooling mechanisms. Based on the derived energy distribution of nonthermal electrons, we model the radio synchrotron spectrum of the shocked ISM. For the 15 nearby RQ AGNs hosting UFOs, we investigate the shocked ISM parameters required to model their observed radio spectra based on X-ray observations and measured UFO velocities. Radio spectra of 11 out of 15 nearby RQ AGNs would be explained by the AGN disk wind model. This is a compelling indication that shock interactions between AGN disk winds and the ISM could indeed be the source of their radio emissions. The typical predicted source size and magnetic field strength are several 100 pc and 0.1 mG, respectively. We also discuss whether our prediction can be tested by future radio observations.
No Signature of the Birth Environment of Exoplanets from Their Host Stars’ Mahalanobis Phase Space
Authors: Blaylock-Squibbs George A. , Parker Richard J. , Daffern-Powell Emma C. 
Published: June 2024

Abstract
The architectures of extrasolar planetary systems often deviate considerably from the “standard” model for planet formation, which is largely based on our own solar system. In particular, gas giants on close orbits are not predicted by planet formation theory and so some processes are thought to move the planets closer to their host stars. Recent research has suggested that hot-Jupiter host stars display a different phase space compared to stars that do not host hot Jupiters. This has been attributed to these stars forming in star-forming regions of high stellar density, where dynamical interactions with passing stars have perturbed the planets. We test this hypothesis by quantifying the phase space of planet-hosting stars in dynamical N-body simulations of star-forming regions. We find that stars that retain their planets have a higher phase space than nonhosts, regardless of their initial physical density. This is because an imprint of the kinematic substructure from the regions birth is retained, as these stars have experienced fewer and less disruptive encounters than stars whose planets have been liberated and become free-floating. However, host stars whose planets remain bound but have had their orbits significantly altered by dynamical encounters are also primarily found in high phase space regimes. We therefore corroborate other research in this area that has suggested the high phase space of hot-Jupiter host stars is not caused by dynamical encounters or stellar clustering, but rather reflects an age bias in that these stars are (kinematically) younger than other exoplanet host stars.
Genetic and morphological differences among relict marginal occurrences of Stenobothrus eurasius (Orthoptera)
Authors: Kenyeres Zoltán , Bauer Norbert , Kociński Maciej , Grzywacz Beata 
Published: June 2024

Steppes form large zonal habitats in Asia but only consist of localised outposts in Europe. An ideal subject for the study of differences within species between the main steppe zone and the localized more western outposts is the Orthopteran Stenobothrus eurasius, widespread across the Siberian and Central Asian steppes but present only in isolated relic populations at the western edge of its area. We used genetic and morphological analyses to detect possible differences among these relic populations.
We carried out a study on morphological parameters of wings in parallel with the comparison of four DNA fragments (cytochrome c oxidase subunit I, 12S rRNA and the mtDNA control region, cytochrome B, nuclear internal transcribed spacers plus the 5.8S rRNA region) involving 15 extrazonal populations of the species. St. nigromaculatus was used as an outgroup taxon in the genetic analyses.
Variability of the morphological characters of St. eurasius individuals was higher within the regions than amongst the regions. The two Stenobothrus species were not separated based on the CR gene. Samples of both Stenobothrus species were separated on the COI, cytB and ITS1-5.8S-ITS2 phylogenetic trees with high support (PP = 1) in Bayesian analyses but clear genetic lineages were not revealed, and populations of the focal species were not grouped according to their geographic locations. The similarity of this species in different steppe outposts supports the hypothesis that St. eurasius was widespread in the more extensive steppe areas that were once present, but the extension of agricultural landuse reduced the steppe habitats resulting in the current patchy distribution of St. eurasius limited to the remaining habitats.
S’ajuster par le bas ou par le haut aux inégalités
Authors: Dodier Nicolas 
Published: June 2024

L’article montre en quoi l’ajustement aux inégalités qui caractérisent notre monde est à l’origine d’une tension entre deux stratégies, « par le haut » et « par le bas », qui structure à différentes échelles l’action humanitaire internationale. L’article s’appuie sur les premiers résultats d’une enquête, basée sur la consultation d’archives et la réalisation d’entretiens, relative à la mise en œuvre de programmes de chirurgie par l’organisation Médecins Sans Frontières (MSF). Il suggère une approche qui soit en mesure d’étudier, au-delà de cet exemple, les tensions qui structurent les composantes épistémiques de la normativité pratique déployée par les professionnels de l’humanitaire.
An Unusual Case of Pericardial Calcification
Authors: Varghese Teena Mary , Kareem Hashir , Vijayaraghavan Govindan 
Published: June 2024

Abstract
The pericardium is normally, a rigid, avascular, fibrous sac. Its primary functions are to anchor, lubricate, and prevent overdistention of the cardiac chambers. Normally, the pericardium does not contain any calcium deposits; calcification may be a sign of underlying inflammation. Pericardial calcification alone is generally asymptomatic; however, signs and symptoms usually result secondary to the constrictive physiology caused by the rigid pericardium. But again, it should be noted that only 25% of patients with constriction have pericardial calcification. Our patient was a 58-year-old male with slowly progressive symptoms of abdominal distension and pedal edema, who was evaluated and was found to have calcification of the pericardium, in quite unusual locations, resulting in even more unusual complications.
Utilization of Modified Touchdown qPCR to Enhance Sensitivity and Specificity for Genes with Restricted Expression and Low Optimum Temperature Primers
Authors: Rahmi Koyuki Atifa , Khotimah Husnul , Rohman Mohammad Saifur 
Published: June 2024

Abstract

Background:
Quantitative polymerase chain reaction (qPCR) is one of the most used methods to analyze gene expression. However, if the annealing temperature in the qPCR cycle is lower than 55°C, nonspecific amplification may occur. On the other hand, some sets of primers can only function optimally at the annealing temperature below 55°C. Thus, a protocol allowing both specific amplification and large yield in low annealing temperature is needed.

Methods:
qPCR on the target ribosomal protein L13a (rpl13a) and natriuretic peptide A (nppa) from samples of zebrafish embryos and larvae was performed in triplicates using three different protocols: routine qPCR, gradient qPCR, and modified touchdown qPCR. The cycle of quantification (Cq) value and melt peak data were compared between the routine or gradient qPCR and the modified touchdown qPCR.

Results:
For rpl13a that was adequately and specifically amplified by both routine and touchdown qPCR, modified touchdown qPCR decreased the average Cq by 3.68–4.66 (P < 0.05). For nppa, a gene with restricted expression that could only be amplified substantially but nonspecifically at the annealing temperature of 50°C, modified touchdown qPCR increased the amplification specificity by forming only one melt peak during melt curve analysis and yielding a substantial amount of amplicon with the Cq of 22.48–22.51.

Conclusions:
The modified touchdown qPCR with low final annealing temperature was able to produce specific amplification with better yield and detection sensitivity. This method is especially useful for primer sets with low optimum annealing temperature.
Correlation between Fatty Acid Transport Proteins and Phosphoinositide 3-Kinase Pathway in Breast Cancer
Authors: Acharya Ranjitha , Nalilu Suchetha Kumari , Shetty Shilpa Sharathraj , Shetty Abhijith Sudhakar , Monteiro Flama , Ganeshkodi Roopashree Padmanabha 
Published: June 2024

AbstractBackground:Breast cancer (BC) is currently the fifth largest cause of mortality worldwide and has become the most frequent type of cancer. Fatty acid transport proteins (FATPs) assist cancer cells in meeting their higher metabolic needs by increasing fatty acid uptake, which is a significant source of energy for cancer cells. The phosphoinositide 3-kinase/protein kinase B/mammalian target of the rapamycin (PI3K/Akt/mTOR) pathway is an important signaling pathway that coordinates the uptake and utilization of various nutrients, including fatty acids. The current study aimed to correlate the FATPs with thePI3K/Akt/mTORpathway in BC.Methods:Eighty serum samples were collected from BC and control subjects after obtaining an informed consent form. Total ribonucleic acid (RNA) was isolated, and the relative messenger RNA (mRNA) expression ofPI3K, Akt, andmTORwas analyzed by a reverse transcriptase-quantitative polymerase chain reaction. Serum FATPs were estimated using commercially available enzyme-linked immunoassay kits.P< 0.05 was indicated as statistically significant.Results:The serum FATPs in subjects with BC differed significantly compared to the control. Relative mRNA expression ofPI3K, Akt, andmTORdiffered significantly between the groups. Further, on correlating the serum FATPs with PI3K-related signaling molecules showed a significant positive correlation within BC subjects.Conclusion:Significant positive correlation between FATPs and thePI3K, Akt, andmTORpathway suggests a crucial role of FATPs in promoting BC.
Serum Acetylcarnitine as a Diagnostic Marker in Depression Episodes
Authors: Varma R. Sandeep , Kumar B. G. Prashanth , Krishna C. S. Muralidhar 
Published: June 2024

AbstractBackground:Depression is a serious public health concern due to its prevalence and associated discomfort, dysfunction, morbidity, and economic impact. Depression is more prevalent in women than in males. There is a need to investigate the course of depressive disorders in India to identify the necessity and duration of ongoing treatment. Studies should also assess cost-effective treatment strategies that can be easily implemented in primary care settings to successfully treat depression.Methods:This study aimed to estimate the Serum L-Acetyl Carnitine (LAC) levels in depressive episodes, mainly to find a correlation between the levels and depression and also to correlate the values to the severity of depression with a depression rating scale like Montgomery–Åsberg Depression Rating Scale (MADRS). LAC levels were estimated using an enzyme-linked immunosorbent assay kit.Results:A cross-sectional study was conducted with 60 individuals after obtaining their informed consent. This included 30 cases of diagnosed depression and 30 age and sex-matched normal controls. The diagnosed depressive episodes were rated in MADRS, and a score was assigned based on the same. The results were tabulated and statistically analyzed. The mean age of the case group was 41.37 ± 11.32 and control group was 41.50 ± 14.37. The incidence of depressive symptoms was higher in females (53%) than males (47%). The incidence of depressive symptoms was higher in the 41–50-year age group than in any other group. The acetyl carnitine-LAC levels were significantly decreased in patients with depressive episodes (950.7 ± 902.7) compared to the control (1799.6 ± 67.1), respectively. The Pearson’s correlation shows there is a strong negative correlation between the MADRS score and the levels of acetylcarnitine in the cases which was statistically significant,P< 0.001.Conclusions:LAC may have an important role in the pathophysiology of depression by its epigenetic action on metabotropic glutamate receptors and the decrease in the brain tissue may induce depressive symptoms, and consequently, their supplementation causes a rapid antidepressant effect. Hence, it could be a useful biochemical marker for the diagnosis of depression and also an effective for the treatment of depression.
Isolation and Identification of Vibrio Species from Different Types of Water Sources Along with Their Drug Susceptible Pattern
Authors: Sultana Raquiba , Mahmud Al , Koli Sayad Mahmud , Nayema Jannatul , Ghosh Aboni , Sushree Susmita Banik , Shom Pranta , Siddiqui Tanvir Ahmed , Das Kamal Kanta , Acharjee Mrityunjoy 
Published: June 2024

Abstract

Background:
Human activities are almost usually the cause of contaminated water supplies and places with large population densities and intensive land usage are particularly prone to pollution of drinking water sources. It is challenging to detoxify polluted water sources. Cholera is an acute form of diarrheal disease that plagued human civilization over the centuries. Vibrio spp., commonly found in aquatic environments, are the most common cause of bacterial gastroenteritis in the world, those may spread to humans through the ingestion of contaminated drinking water or exposure to seawater.

Methods:
In the present study, a total of 12 samples were collected from four types of water sources for the isolation of Vibrio spp. along with their drug-resistant pattern through conventional, biochemical, and antibiotic disc diffusion methods.

Results:
The samples were enriched into alkaline peptone water and then inoculated into culture media such as nutrient agar, MacConkey, and TCBs agar medium. After incubation for 24 h at 37°C on TCBS agar, yellow and green colonies were screened out for biochemical identification. Nonsucrose-fermenting Vibrio parahaemolyticus, Vibrio mimicus, and Vibrio vulnificus showed green colonies, and sucrose-fermenting Vibrio cholera and Vibrio alginolyticus showed yellow colonies on TCBS. The antibiotics ERY (15 μg), PCN (10 μg), CEX (30 μg), and VAN (30 μg) were completely resistant while the more effective antibiotics against Vibrio spp. were SXT (25 μg), CHL (30 μg), and GEN (30 μg). However, ciprofloxacin and nitrofurantoin showed moderate efficacy.

Conclusion:
To expand current knowledge on the occurrence, ecological niche, and persistence of potential human pathogenic Vibrio spp. in aquatic environments, the extensive laboratory experiment is required. To sum up, this kind of information is crucial for bringing attention to the existence of Vibrio spp. and enabling prompt implementation of preventive measures.
Molecular Identification of Endophytic Fungi isolated from Tragopogon graminifolius and Investigation of Their Biological Activities
Authors: Ebadi Mostafa , Mollaei Saeed , Tahmouresi Hossein , Farnia Poopak 
Published: June 2024

Abstract

Background:
Endophytic fungi live inside the plant tissue, and can produce bioactive compounds.

Methods:
Herein, the molecular identification, phenols metabolites analysis, and biological properties (enzymatic and antioxidant) of endophytic fungi isolated from the aerial parts of Tragopogon graminifolius were studied. The enzyme produced by endophytic fungi was tested by the formation of a clear zone/pink around the colonies. The 2, 2-diphenyl-1-picrylhydrazyl method was used for the investigation antioxidant properties of isolated fungi. Moreover, the total flavonoid and phenol contents were studied using aluminum chloride colorimetric and Folin–Ciocalteu methods, respectively. Furthermore, the phenolic acids analysis was performed using high-performance liquid chromatography.

Results:
In this study, two isolates were identified (Talaromyces amestolkiae and Rhizopus oryzae). Evaluation of the enzymatic activities indicated that R. oryzae had the ability to produce amylase and pectinase, whereas T. amestolkiae exhibited extracellular activity for amylase, L-asparaginase, and pectinase. The result of the antioxidant property study indicated that T. amestolkiae had the highest antioxidant property and its IC50 value was 617 μg/mL. Moreover, these fungi had the highest flavonoids and phenols amounts. The phenolic acid analysis indicated that m-coumaric acid was the major phenolic acid which was determined by the studied fungi.

Conclusion:
This report was the first study of endophytic fungi from T. graminifolius, and the outcome of this study can be a way to produce m-coumaric acid at an industrial scale.
No Association between Helicobacter pylori and Gastroesophageal Reflux Disease: A Comprehensive Risk Factor Analysis in North Indian Patients
Authors: Gehlot Valentina , Mathur Akshita , Das Kunal , Mahant Shweta , Das Rajashree 
Published: June 2024

Abstract

Background:
The relationship between gastroesophageal reflux disease (GERD) and Helicobacter pylori infection is a complicated topic. This study aimed to evaluate the association between H. pylori infection and GERD and identify the associated risk factors in North India.

Methods:
All individuals who were referred for an endoscopy because they had dyspepsia were included in a cross-sectional study. Using endoscopic assessment, GERD was diagnosed. As a comparison group, patients with normal esophageal function were chosen. H. pylori was cultured and genotyped to assess the virulent genes such as cagA, vacA, and iceA. The relationship of H. pylori infection with GERD and its associated risk factors were estimated with Chi-square analysis, odds ratios, and 95% confidence intervals using multiple logistic regression analysis.

Results:
In total, 420 patients were included in this study, of whom 335 (79.8%) had GERD. The mean age was 44.01 ± 16.52 years. Overall, 143 (34%) patients were positive for H. pylori infection. cagA-negative H. pylori isolates were significantly associated with the GERD group. Variables such as gender, age, alcohol, smoking, body mass index (BMI), smoking, and hiatus hernia in patients had no significant association with H. pylori infection. However, increased age, gender, Frequency Scale for the Symptoms of GERD (FSSG) score, BMI, and presence of hiatus hernia were significantly associated with the GERD group.

Conclusion:
In our results, there was no association between H. pylori infection and GERD. The risk factors for GERD were age, gender, FSSG score, BMI, and hiatus hernia. Further studies are recommended.