bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self‐Powered Linear Pressure Sensor Based on MXene/CNT Nanofluid Membrane
Authors: Chen Kun , Gao Mengyao , Liu Xiaoqing , Xing Haonan , Sun Huili , Wang Huatang , Lou Aosen , Song Xiaohui , Liu Weijie , Guo Haizhong 
Published: February 2025

AbstractIon channels, which own efficient, accurate, and selective ion transport ability, play a key role in maintaining cell homeostasis, participating in signal transduction, and other physiological processes in organisms. However, the inherent complexity and uncontrollability of ion channels in nature restrict their direct use in technical applications. In order to address the application requirements of specific fields, nanochannels have been designed to simulate and optimize the functional characteristics of biological ion channels. Herein, two‐dimensional (2D) nanochannels based on MXene/carbon nanotube (CNT) composite membrane are constructed, with their ion transport mechanisms analyzed using molecular dynamics simulations. In addition, the ion transport characteristics in nanochannels under the influence of external environment of pressure are further explored and the current density can reach up to 315 nA cm−2. Based on the ion selectivity of nanochannels in MXene/CNT composite membrane, a self‐powered linear pressure sensor is designed, which shows an ultrafast response (51.3 ms) and recovery time (60.2 ms), respectively. Thus, the sensor is capable of monitoring a range of human activities ranging from subtle deformations to vigorous body movements. Furthermore, the sensor can readily differentiate a range of sounds through air vibration and exhibit enormous potential in sound visualization technology.
Transient Liquid Induced Hierarchical Structure Contributes to High Thermoelectric Performance in Ag2Se
Authors: Kitthonbancha Peeranut , Liu Wei‐Di , Li Meng , Pinitsoontorn Supree , Chen Zhi‐Gang 
Published: February 2025

AbstractOwing to the intrinsic high thermoelectric performance, Ag2Se is a promising alternative for traditional near‐room temperature Bi2Te3‐based materials. In this study, a Na2SO3 solution has been used as the transient liquid during the modified cold sintering process to induce a hierarchical structure, including micropores, nanopores, sub‐nanopores, and additional nanoscale Na2SO3 residuals. Such a hierarchical structure contributes to an ultralow lattice thermal conductivity of 0.18 W m−1 K−1 at ≈300 K in the Ag2Se‐30%Na2SO3. Additionally, extra Se vacancies further optimize the carrier concentration to ≈5.6 × 1018 cm−3, leading to a high power factor of ≈25 µW cm−1 K−2 at ≈300 K in the Ag2Se‐30%NS. Consequently, due to the synergistic effects of high power factor and low lattice thermal conductivity, an ultrahigh room‐temperature figure of merit of 1.04 in the Ag2Se‐30%Na2SO3. The study demonstrates that introducing transient liquid solutions in the modified cold sintering process can effectively achieve specific structural engineering and high thermoelectric performance.
Modulation of Single‐Iron‐Atom Coordination Environment Toward Three‐Electron Oxygen Reduction for Photocatalytic CH4 Conversion to CH3OH
Authors: Li Laiquan , Shi Xiuwen , Liu Lingyue , Tu Ying , Liu Yuhang , Zhang Yuhang , Yang Hong Bin , Dou Shixue , Liu Bin 
Published: February 2025

AbstractBy modifying the coordination environment of single‐Fe‐atom active site, effective regulation of the photocatalytic oxygen reduction pathway can be achieved to attain high activity for photocatalytic oxidation of CH4 to CH3OH in an aqueous solution. A comprehensive investigation is conducted to study the impact of different coordination numbers of single Fe atoms on photocatalytic CH4 oxidation reaction over carbon nitride. Among which, Fe1/C3‐xN4 with a Fe‐N3 coordination exhibit an exceptional photocatalytic performance in CH4 oxidation, reaching a remarkable methanol yield of 928.27 µmol gcat−1, much higher than Fe1/C3N4 and Fe1/C3N4‐x (308.47 and 473.26 µmol gcat−1, respectively). Based on a collection of in situ characterizations and time‐dependent density functional theory calculations, it is determined that Fe1/C3‐xN4 with an optimal coordination number possesses the optimized electronic configuration that enables three‐electron oxygen reduction to generate hydroxyl radicals for photocatalytic conversion of CH4 to CH3OH.
Advances in Engineered Phages for Disease Treatment
Authors: Hou Xiaolin , Zhai Lin , Fu Laiying , Lu Junna , Guo Peilin , Zhang Yu , Zheng Diwei , Ma Guanghui 
Published: February 2025

AbstractPhage therapy presents a promising solution for combating multidrug‐resistant (MDR) bacterial infections and other bacteria‐related diseases, attributed to their innate ability to target and lyse bacteria. Recent clinical successes, particularly in treating MDR‐related respiratory and post‐surgical infections, validated the therapeutic potential of phage therapy. However, the complex microenvironment within the human body poses significant challenges to phage activity and efficacy in vivo. To overcome these barriers, recent advances in phage engineering have aimed to enhance targeting accuracy, improve stability and survivability, and explore synergistic combinations with other therapeutic modalities. This review provides a comprehensive overview of phage therapy, emphasizing the application of engineered phages in antibacterial therapy, tumor therapy, and vaccine development. Furthermore, the review highlights the current challenges and future trends for advancing phage therapy toward broader clinical applications.
A Secure Data Storage Architecture for Internet of Things Using a Hybrid Whale‐Based Harris Hawk Optimization Algorithm and Fuzzy‐Based Secure Clustering
Authors: Daniel D. J. Joel Devadass , Jagadeesh S. 
Published: February 2025

ABSTRACTRecently, the most common and challenging issue in the Internet of Things (IoT) is to establish end‐to‐end authentication. The IoT is developed to enable data exchange and connectivity between systems and devices. Here, the security and Quality of Services (QoS) are important problems because of unauthenticated cryptography mechanisms and inefficient route selection. So, we introduced the three‐tier system architecture of secure data storage in IoT. The fuzzy‐based secure cluster formation (F‐SCF) is used to aggregate the sensor nodes into multiple clusters in the initial tier. The secure routes with multiple QoS metrics are selected with the help of a novel Whale optimization‐based Harris Hawks optimization (W‐HHO) algorithm. The parallel advanced encrypted standard with cipher block chaining (PAES‐CBC) is introduced for data security. Based on the selection criteria, the fuzzy weighted‐based order selection with an equivalent ideal solution (FW‐OSEIS) is proposed to select the optimal open flow switches (O
fs). By integrating W‐HHO with advanced fuzzy logic, the proposed method optimizes secure route selection and cluster formation, achieving enhanced data security, energy efficiency, and quality of service (QoS) in large‐scale IoT environments. Experimentally, the simulation works are handles in Cooja software and the performance of different kinds of QoS metrics such as packet delivery ratio (PDR), throughput, network lifetime, and end‐to‐end delay is evaluated. Experimental results demonstrate that the proposed architecture achieves a higher PDR of 95.3%, extends network lifetime by 23%, and improves throughput by 18% compared to existing methods, while maintaining a low packet drop ratio and reduced end‐to‐end delay, thereby validating its effectiveness in secure and efficient IoT data management.
Molecular Ordering Determines the Formation of Strong Gels After Retrogradation of Low‐Viscosity Potato Starch
Authors: Hidalgo Bastian , Koporcic Milenka , Otsu Javier , Mujica B. , Castro Melany , Videla Valeria , Quintero Montserrat , Gremasqui Ileana de los Angeles , Alarcón‐Moyano Jessica , Díaz‐Calderón Paulo 
Published: February 2025

ABSTRACTThe aim of this study was to characterize a low‐viscosity potato starch (LVPS) in terms of pasting properties and kinetics of retrogradation. The pasting properties of a commercial sample of LVPS were measured by Rapid‐Visco‐Analysis, while the kinetics of retrogradation were assessed following changes in gel strength by mechanical tests (after storage 24 and 168 h, 4°C) and viscoelasticity by dynamic time sweep (4 h, 4°C). Analysis was complemented by measurements of cold‐water solubility, thermal properties, Fourier‐transformed infrared (FTIR) spectroscopy, polarized microscopy, size distribution, and x‐ray diffraction. A sample of normal potato starch (NPS) was used as a control for comparison. LVPS showed significant differences in pasting properties compared to NPS, with much lower pasting parameters (final viscosity 57.9 cP for LVPS, 2991.6 cP for NPS). However, the dynamic time sweep showed that LVPS behaved as a strong gel during retrogradation, which was consistent with the higher gel strength obtained by LVPS after storage. Mechanical and rheological response could be explained by differences in crystallinity and number of oxygen bonds, as suggested by the FTIR spectra. However, the native molecular ordering was different in LVPS, which would determine how amylose leaches during gelatinization and define how self‐association and self‐assembly take place during retrogradation. Our results also showed that LVPS was not soluble in cold‐water, which was consistent with calorimetric data and polarized microscopy images. Hence, LVPS could be further used in applications requiring a starch capable of good mechanical response, but from starchy suspensions with low viscosity.
Application of low‐emission cement CEM II/C in concrete made with low‐effort processed recycled aggregates
Authors: Hron Johannes , Zeman Oliver , Troll Pascal , Pohl Hannah , Pichler Thomas , Bergmeister Konrad , Voit Klaus 
Published: February 2025

AbstractThe present study investigates the applicability of recycled concrete aggregates (RCA) for use in structural concrete made with low‐emission cement CEM II/C‐M (global warming potential of 377 kg CO2,eqv.). The aim is to show the potential of RCA processed with minimal energy, water, and economic expenditure. The combination of recycled aggregates with CEM II/C‐M fulfills both, a significant reduction in resource consumption, as well as a reduction in CO2 emissions compared to ordinary structural concrete. The experimental campaign included the investigation of RCA from two different sources with different low‐effort processing procedures and the manufacture of recycled concrete with substitution rates from 25% up to 100%. As a reference, a concrete a mixture using 100% natural aggregates was produced. The fresh and hardened concrete properties were determined considering the age of up to 1 year to take into account the known slower hydration behavior of CEM II/C‐M. The results show a potential of low‐effort processed RCA, as well as the challenges occurring by the avoidance of a washing step during processing. Furthermore, when using low‐emission cement CEM II/C, an assessment of the concrete strength at a later point in time than the usual 28 days is suggested. This approach better takes account of the final strength properties and avoids producing over‐strengthened concrete elements.
A Narrative Review of the Debate on the So-Called International Crime Drop
Authors: Aebi Marcelo F. 
Published: February 2025

Abstract
This chapter provides a comprehensive review of the scholarly discourse surrounding the concept of an "international crime drop" during the 1990s and 2000s, examining four distinct interpretative narratives that have shaped our understanding of global crime trends. Through a chronological analysis of key publications, conferences, and research initiatives, the chapter traces how the concept evolved from observations of declining crime rates in the United States to broader international applications. The author identifies and analyzes four major narratives: the All-American narrative, focusing on U.S. crime trends and explanations; the Lausanne School narrative, emphasizing European variations and the role of technological change; the Crime and Justice narrative, offering a more skeptical view of violent crime trends; and the Security Hypothesis narrative, attributing declines primarily to improved security measures. The review reveals significant methodological and theoretical tensions between these perspectives, particularly regarding the interpretation of violent crime trends in continental Europe and the role of cybercrime. While there is broad agreement on declining rates of property crimes and homicides in many Western countries since the 1990s, the chapter shows that the notion of a universal "international crime drop" oversimplifies complex regional variations and emerging crime patterns. The author argues that understanding contemporary crime trends requires considering the transformation to a hybrid society, where traditional offline crimes coexist with rising online and hybrid offenses. The chapter concludes by highlighting the need for more nuanced, context-sensitive approaches to analyzing crime trends that account for technological change, regional variations, and the growing importance of cybercrime in contemporary societies.
Gesetzliche Zahlungsmittel in elektronischer Form und demokratische Staaten
Authors: Pagliarin Carola 
Published: February 2025

Zusammenfassung
Der vorliegende Beitrag enthält erste Überlegungen zur möglichen Einführung von digitalen staatlichen Währungen – und insbesondere zum digitalen Euro. Die Ausführungen werden dabei unter dem Gesichtspunkt angestrengt, welche Auswirkungen eine solche Entwicklung auf die Form demokratischer Staaten haben könnte und inwieweit eine Regulierung künftig erforderlich werden wird.
Feasibility of Utilizing Continuous Records from Weak And Strong-Motion Recorder Channels of Permanent Stations for Horizontal To Vertical Spectral Ratio (HVSR) Analysis During Calm-Day Conditions
Authors: Senkaya Mustafa 
Published: February 2025

Abstract
The proposed paper assesses the feasibility of using continuous records acquired from weak and strong-motion recorder channels of permanent earthquake observation stations under calm-day conditions for the HVSR method. The analyses were conducted on 60 tri-axial ambient noise data through HN channels from strong-motion recorders and BH, HH (or EH) channels from weak-motion recorders from 25 stations belonging to various soil and topography classes in the INGV network of Italy. The accuracy and reliability of the proposed HVSR curves were evaluated by benchmarking them with predefined original HVSR curves for each station, using statistical metrics such as the Pearson correlation coefficient and mean absolute error (MAE). The findings demonstrate that weak-motion recorder channels, especially HH and EH, acquire ambient noise, which serves as the primary data for the HVSR method, with higher PSD levels than strong-motion channels due to their inherently lower self-noise threshold. Therefore, while HVSR curves derived through BH channels indicate an average correlation of 84% and MAE of 12%, HH-EH channels demonstrate 91% and %12, respectively. Conversely, HN channels exhibit lower correlation (28%) and higher MAE (31%). Furthermore, topography and soil class influence PSD values, with T1 and C classes exhibiting the highest levels. However, variations in performance across different topographic and soil classes are less pronounced. The analyses suggest that the channel type plays a more critical role in HVSR analysis. This finding highlights the importance of selecting the appropriate channel for accurate HVSR analysis using permanent stations.
Exposure to diesel exhaust particles impairs takeoff but not subsequent homing and foraging behavior of workers of the buff-tailed bumblebee Bombus terrestris
Authors: Seidenath D. , Pölloth S. , Mittereder A. , Hillenbrand T. , Brüggemann D. , Schott M. , Laforsch C. , Otti O. , Feldhaar H. 
Published: February 2025

Abstract
The loss of insect diversity and biomass has been documented in many terrestrial ecosystems. Drivers of this insect decline include climate change, habitat degradation, and pollution. Exposure to airborne particulate matter, such as diesel exhaust particles, may be harmful, especially for insects around urban or industrial areas. Ecotoxicological experiments have shown that chronic oral uptake of diesel exhaust particles can result in higher mortality and changes in the gut microbiome in bumblebees. However, how such effects manifest under natural conditions is still largely unknown, especially effects on foraging activity. Here, we exposed workers of the bumblebee Bombus terrestris to diesel exhaust particles in the field at distances of 380 m and 1100 m from their colony. We measured the time until bumblebees took off, the duration of their homing flight after a one-time exposure, and subsequent foraging activity over 1.5 days, recording the number and duration of the foraging flights in comparison to untreated bumblebees. The treated bumblebees needed significantly longer to start their homing flight, caused by some workers that were even unable to take off vertically from the exposure box and performing extensive grooming behavior. Homing flight duration and the subsequent foraging activity did not differ between treated and control workers. It remains unclear why bumblebees struggled to take off after exposure to diesel exhaust particles. This observation needs further investigation to elucidate whether this behavior is induced by particulate matter in general or related to specific physico-chemical properties of the particles inducing a physiological effect.
Digitale Innovationen in der Impfkommunikation
Authors: Böhm Robert , Gross Rian , Forst Sabrina , Reiter Julia , Betsch Cornelia 
Published: February 2025

Zusammenfassung
Trotz des großen Erfolges von Impfungen stellt die zunehmende Impfmüdigkeit eine Bedrohung für die öffentliche Gesundheit dar. Deshalb ist eine effektive Impfkommunikation wichtig. Sowohl personalisierte und bedürfnisgerechte Gespräche zwischen Ärzt*innen und Patient*innen als auch großangelegte standardisierte Impfkampagnen über klassische Medien zählen zu den wichtigsten Werkzeugen, um mögliche Unsicherheiten und Sorgen von Patient*innen zu entkräften, Fehlinformationen zu korrigieren und positive Argumente für den Nutzen von Impfungen zu vermitteln. In diesem Beitrag werden digitale Innovationen für die Impfkommunikation vorgestellt, die Vorteile beider Kommunikationsformen kombinieren und damit wichtige Bausteine für die Impfkommunikation in einer zunehmend digitalisierten Gesellschaft werden können. Wir betrachten 4 digitale Ansätze: soziale Medien, Smartphone-Apps, Chatbots und immersive Technologien (insbesondere virtuelle Realität). Wir beschreiben die Eigenschaften dieser Medien und Technologien, mögliche Zielgruppen für ihre Anwendung, ausgewählte wissenschaftliche Evidenz zu ihrer Effektivität in der Impfkommunikation sowie Forschungslücken und -potenziale. Abschließend machen wir Vorschläge für mögliche Anwendungs- und Einsatzbereiche dieser Ansätze in der Impfkommunikation. Auch wenn die Forschung zu digitalen Innovationen in der Impfkommunikation noch am Anfang steht, sehen wir große Potenziale, diese Ansätze als ergänzende Maßnahmen in umfassende Impfkommunikationsstrategien zu integrieren, um die Effektivität zukünftiger Impfkampagnen zu steigern und die globale Gesundheit nachhaltig zu fördern.
Theranostics using 89Zr/177Lu-labeled antibody targeting erythropoietin-producing hepatocellular A2 (EphA2)
Authors: Watabe Tadashi , Iwasawa Takumi , Kimura Hiroyuki , Shirakami Yoshifumi , Naka Sadahiro , Kaneda Kazuko , Kobayashi Takanori , Omokawa Marina , Yagi Yusuke , Tomiyama Noriyuki , Kato Kazunori 
Published: February 2025

Abstract

Purpose
Erythropoietin-producing hepatocellular A2 (EphA2) is abundantly expressed in various types of cancers. This study aimed to assess the therapeutic effect of 177Lu-labeled EphA2 antibody in combination with PET imaging using 89Zr-labeled antibody.

Methods
An EphA2 monoclonal antibody (mAb) (clone 230-1) was labeled with 89Zr and 177Lu using DFO and NOTA chelators, respectively. HT-1080 (EphA2-expressing human fibrosarcoma) xenograft mice were intravenously administered [89Zr]Zr-EphA2 mAb (n = 6) for PET scanning, and [177Lu]Lu-EphA2 mAb (n = 12) to evaluate the biodistribution and specificity of uptake in HT-1080 xenografts in a blocking study. The antitumor effect was evaluated by administering 10 (n = 9) or 3MBq (n = 9) of [177Lu]Lu-EphA2 mAb, non-radiolabeled EphA2 mAb (n = 6), [177Lu]LuCl3 solution (10MBq, n = 6), or saline solution (control, n = 4) to HT-1080 xenograft mice. Body weight monitoring and preliminary blood tests were performed to evaluate toxicity. Immunohistochemical staining for EphA2 was performed using HT-1080 xenografts.

Results
On [89Zr]Zr-EphA2 mAb PET, a markedly high accumulation was observed in the tumor xenograft 1 day after administration (SUVmax, 11.8 ± 4.98), which increased on day 5 (SUVmax, 20.1 ± 6.42). [177Lu]Lu-EphA2 mAb exhibited excellent uptake and retention in HT-1080 xenografts (49.4 ± 10.8%IA/g at 24 h and 101.8 ± 26.3%IA/g at 72 h after administration). Normal organs did not show high physiological uptake, except for the blood (16.9 ± 0.43%IA/g at 24 h and 16.1 ± 4.9%IA/g at 72 h). The blocking study demonstrated a significant reduction of tumor uptake 24 h after administration (47.2 ± 8.22 vs. 10.7 ± 0.52%IA/g, P = 0.02). Substantial tumor growth inhibition, and complete remission without severe toxicity (6 of 18 mice), was observed in HT-1080 xenograft mice after [177Lu]Lu-EphA2 mAb (3 and 10 MBq) administration. The non-radiolabeled EphA2 mAb showed a minor treatment effect compared with [177Lu]Lu-EphA2 mAb. Immunohistochemical staining revealed high EphA2 expression in the HT-1080 xenografts.

Conclusion
[89Zr]Zr-/[177Lu]Lu-EphA2 mAb demonstrated high retention in tumors, and [177Lu]Lu-EphA2 mAb exhibited marked tumor shrinkage. EphA2 is a promising theranostics target for potential application in various types of cancer.
Harnessing Plant-Derived Terpenoids for Novel Approaches in Combating Bacterial and Parasite Infections in Veterinary and Agricultural Settings
Authors: Wiles Danielle , Pearson Jaclyn S. , Beddoe Travis 
Published: February 2025

Abstract
The rising resistance to conventional antimicrobial therapies in veterinary contexts poses a formidable challenge. While various innovative treatment strategies for pathogenic infections have emerged, their success still needs to be improved, warranting continued research. Recent investigations into natural products as potential sources for biologically active therapeutics have gained traction. Phytochemicals present a promising alternative in combating a spectrum of pathogens, including bacteria, fungi and parasites. One such class of phytochemicals with mounting potential is the structurally diverse terpenes. These chemicals contribute to plants’ characteristic odour and medicinal effects and have been widely investigated in the scientific literature for their exceptional antibacterial activity. Their efficacy is demonstrated through diverse mechanisms, encompassing damage to bacterial membranes, suppression of virulence factors, and interference with enzymes, toxins, and biofilm formation. This review comprehensively examines terpenes’ in vitro and in vivo activity and their derivatives against pathogens, elucidating their potential against antimicrobial resistance (AMR) and the underlying mechanisms specific to each terpene class. The findings underscore the burgeoning potential of terpene therapy as a viable alternative or supplementary approach to conventional antibiotics in addressing bacterial and parasitic infections in livestock and companion animals.