bluuebunny/crossref_metadata_2025_split huggingface dataset:
mHealth Apps for Dementia, Alzheimer Disease, and Other Neurocognitive Disorders: Systematic Search and Environmental Scan
Authors: Ali Suad , Alizai Hira , Hagos Delal Jemal , Rubio Sindy Ramos , Calabia Dale , Serrano Jimenez Penelope , Senthil Vinuu Aarif , Appel Lora 
Published: April 2024

Background
Lifestyle behaviors including exercise, sleep, diet, stress, mental stimulation, and social interaction significantly impact the likelihood of developing dementia. Mobile health (mHealth) apps have been valuable tools in addressing these lifestyle behaviors for general health and well-being, and there is growing recognition of their potential use for brain health and dementia prevention. Effective apps must be evidence-based and safeguard user data, addressing gaps in the current state of dementia-related mHealth apps.

Objective
This study aims to describe the scope of available apps for dementia prevention and risk factors, highlighting gaps and suggesting a path forward for future development.

Methods
A systematic search of mobile app stores, peer-reviewed literature, dementia and Alzheimer association websites, and browser searches was conducted from October 19, 2022, to November 2, 2022. A total of 1044 mHealth apps were retrieved. After screening, 152 apps met the inclusion criteria and were coded by paired, independent reviewers using an extraction framework. The framework was adapted from the Silberg scale, other scoping reviews of mHealth apps for similar populations, and background research on modifiable dementia risk factors. Coded elements included evidence-based and expert credibility, app features, lifestyle elements of focus, and privacy and security.

Results
Of the 152 apps that met the final selection criteria, 88 (57.9%) addressed modifiable lifestyle behaviors associated with reducing dementia risk. However, many of these apps (59/152, 38.8%) only addressed one lifestyle behavior, with mental stimulation being the most frequently addressed. More than half (84/152, 55.2%) scored 2 points out of 9 on the Silberg scale, with a mean score of 2.4 (SD 1.0) points. Most of the 152 apps did not disclose essential information: 120 (78.9%) did not disclose expert consultation, 125 (82.2%) did not disclose evidence-based information, 146 (96.1%) did not disclose author credentials, and 134 (88.2%) did not disclose their information sources. In addition, 105 (69.2%) apps did not disclose adherence to data privacy and security practices.

Conclusions
There is an opportunity for mHealth apps to support individuals in engaging in behaviors linked to reducing dementia risk. While there is a market for these products, there is a lack of dementia-related apps focused on multiple lifestyle behaviors. Gaps in the rigor of app development regarding evidence base, credibility, and adherence to data privacy and security standards must be addressed. Following established and validated guidelines will be necessary for dementia-related apps to be effective and advance successfully.
Mediterranean Diet Information on TikTok and Implications for Digital Health Promotion Research: Social Media Content Analysis
Authors: Raber Margaret , Allen Haley , Huang Sophia , Vazquez Maria , Warner Echo , Thompson Debbe 
Published: April 2024

Background
The Mediterranean diet has been linked to reduced risk for several cardiometabolic diseases. The lack of a clear definition of the Mediterranean diet in the scientific literature and the documented proliferation of nutrition misinformation on the internet suggest the potential for confusion among consumers seeking web-based Mediterranean diet information.

Objective
We conducted a social media content analysis of information about the Mediterranean diet on the influential social media platform, TikTok, to examine public discourse about the diet and identify potential areas of misinformation. We then analyzed these findings in the context of health promotion to identify potential challenges and opportunities for the use of TikTok in promoting the Mediterranean diet for healthy living.

Methods
The first-appearing 202 TikTok posts that resulted from a search of the hashtag #mediterraneandiet were downloaded and qualitatively examined. Post features and characteristics, poster information, and engagement metrics were extracted and synthesized across posts. Posts were categorized as those created by health professionals and those created by nonhealth professionals based on poster-reported credentials. In addition to descriptive statistics of the entire sample, we compared posts created by professionals and nonprofessionals for content using chi-square tests.

Results
TikTok posts varied in content, but posts that were developed by health professionals versus nonprofessionals were more likely to offer a definition of the Mediterranean diet (16/106, 15.1% vs 2/96, 2.1%; P=.001), use scientific citations to support claims (26/106, 24.5% vs 0/96, 0%; P<.001), and discuss specific nutrients (33/106, 31.1% vs 6/96, 6.3%; P<.001) and diseases related to the diet (27/106, 25.5% vs 5/96, 5.2%; P<.001) compared to posts created by nonhealth professionals.

Conclusions
Social media holds promise as a venue to promote the Mediterranean diet, but the variability in information found in this study highlights the need to create clear definitions about the diet and its components when developing Mediterranean diet interventions that use new media structures.
Acceptability, Effectiveness, and Roles of mHealth Applications in Supporting Cancer Pain Self-Management: Integrative Review
Authors: Wu Weizi , Graziano Teresa , Salner Andrew , Chen Ming-Hui , Judge Michelle P , Cong Xiaomei , Xu Wanli 
Published: April 2024

Background
Cancer pain remains highly prevalent and persistent throughout survivorship, and it is crucial to investigate the potential of leveraging the advanced features of mobile health (mHealth) apps to empower individuals to self-manage their pain.

Objective
This review aims to comprehensively understand the acceptability, users’ experiences, and effectiveness of mHealth apps in supporting cancer pain self-management.

Methods
We conducted an integrative review following Souza and Whittemore and Knafl’s 6 review processes. Literature was searched in PubMed, Scopus, CINAHL Plus with Full Text, PsycINFO, and Embase, from 2013 to 2023. Keywords including “cancer patients,” “pain,” “self-management,” “mHealth applications,” and relevant synonyms were used in the search. The Johns Hopkins research evidence appraisal tool was used to evaluate the quality of eligible studies. A narrative synthesis was conducted to analyze the extracted data.

Results
A total of 20 studies were included, with the overall quality rated as high (n=15) to good (n=5). Using mHealth apps to monitor and manage pain was acceptable for most patients with cancer. The internal consistency of the mHealth in measuring pain was 0.96. The reported daily assessment or engagement rate ranged from 61.9% to 76.8%. All mHealth apps were designed for multimodal interventions. Participants generally had positive experiences using pain apps, rating them as enjoyable and user-friendly. In addition, 6 studies reported significant improvements in health outcomes, including enhancement in pain remission (severity and intensity), medication adherence, and a reduced frequency of breakthrough pain. The most frequently highlighted roles of mHealth apps included pain monitoring, tracking, reminders, education facilitation, and support coordination.

Conclusions
mHealth apps are effective and acceptable in supporting pain self-management. They offer a promising multi-model approach for patients to monitor, track, and manage their pain. These findings provide evidence-based insights for leveraging mHealth apps to support cancer pain self-management. More high-quality studies are needed to examine the effectiveness of digital technology–based interventions for cancer pain self-management and to identify the facilitators and barriers to their implementation in real-world practice.
Remote Inclusion of Vulnerable Users in mHealth Intervention Design: Retrospective Case Analysis
Authors: Straand Ingjerd J , Baxter Kimberley A , Følstad Asbjørn 
Published: April 2024

Background
Mobile health (mHealth) interventions that promote healthy behaviors or mindsets are a promising avenue to reach vulnerable or at-risk groups. In designing such mHealth interventions, authentic representation of intended participants is essential. The COVID-19 pandemic served as a catalyst for innovation in remote user-centered research methods. The capability of such research methods to effectively engage with vulnerable participants requires inquiry into practice to determine the suitability and appropriateness of these methods.

Objective
In this study, we aimed to explore opportunities and considerations that emerged from involving vulnerable user groups remotely when designing mHealth interventions. Implications and recommendations are presented for researchers and practitioners conducting remote user-centered research with vulnerable populations.

Methods
Remote user-centered research practices from 2 projects involving vulnerable populations in Norway and Australia were examined retrospectively using visual mapping and a reflection-on-action approach. The projects engaged low-income and unemployed groups during the COVID-19 pandemic in user-based evaluation and testing of interactive, web-based mHealth interventions.

Results
Opportunities and considerations were identified as (1) reduced barriers to research inclusion; (2) digital literacy transition; (3) contextualized insights: a window into people’s lives; (4) seamless enactment of roles; and (5) increased flexibility for researchers and participants.

Conclusions
Our findings support the capability and suitability of remote user methods to engage with users from vulnerable groups. Remote methods facilitate recruitment, ease the burden of research participation, level out power imbalances, and provide a rich and relevant environment for user-centered evaluation of mHealth interventions. There is a potential for a much more agile research practice. Future research should consider the privacy impacts of increased access to participants’ environment via webcams and screen share and how technology mediates participants’ action in terms of privacy. The development of support procedures and tools for remote testing of mHealth apps with user participants will be crucial to capitalize on efficiency gains and better protect participants’ privacy.
“The journalistic licence of it all”: Crime, Fiction, and Journalism in David Peace’s Nineteen Seventy Four
Authors: Jiménez Maximiliano 
Published: April 2024

This paper analyzes David Peace’s novel Nineteen Seventy Four (1999), first part of his Red Riding Quartet, to revise how the author uses the dynamics and conceptions of journalism and noir fiction to problematize the concepts of truth and fiction within the genre, on the one hand, and to reflect on the notion of historical past in relation to the present, also subordinated to the crossings between truth and fiction, on the other. By constructing a detective that in this case is embodied by an ambitious journalist in the Yorkshire County of 1974 and exploiting his sordid narrative style, the novel demands comparisons between the contemporary context and the past he fictionalizes through the presence of real-life events. Taking meticulous advantage of the precepts and expectations of noir fiction, the novel leads to a conscientious reading that exacerbates the growing instability of the boundaries between the discourses of reality and fiction in the 21st century. This analysis focuses first on the characterization of the protagonist since the construction of a reporter as the detective and narrator of a noir novel emphasizes the thematization of journalism when seen in relation to the search for truth for profit. Then, it turns to the importance of the journalistic style of the narrator and protagonist, since the narrative characteristics of the text outline very peculiar ways of reading that lead to questioning hegemonic discourses.
Filaggrin Mutation Status and Prevention of Atopic Dermatitis with Maternal Probiotic Supplementation
Authors: Zakiudin Dinastry Pramadita , Thyssen Jacob P. , Zachariae Claus , Videm Vibeke , Øien Torbjørn , Simpson Melanie Rae 
Published: April 2024

The World Allergy Organization recommends probiotics in the prevention of atopic dermatitis in high-risk populations. Mutations in the filaggrin gene (FLG) result in an increased risk of atopic dermatitis through disruption of the skin keratin layer. This exploratory study investigated whether the preventive effect of maternal probiotics was evident in children with and without FLG mutations. DNA was collected from children (n =   228) from the Probiotic in the Prevention of Allergy among Children in Trondheim (ProPACT) study. Samples were analysed for 3 common FLG mutations (R501X, R2447X, and 2282del4). Overall, 7% of children had heterozygous FLG mutations; each child had only one of the 3 mutations. Mutation status had no association with atopic dermatitis (RR = 1.1; 95% CI 0.5 to 2.3). The risk ratio (RR) for having atopic dermatitis following maternal probiotics was 0.6 (95% CI 0.4 to 0.9) and RR was similar if the child expressed an FLG mutation (RR = 0.6; 95% CI 0.1 to 4.1) or wildtype FLG (RR = 0.6; 95% CI 0.4 to 0.9). The preventive effect of probiotics for atopic dermatitis was also evident in children without FLG mutation. Larger confirmatory studies are needed.
On the problem of using neural networks in students' educational activities
Authors: Лопанова Е.В. , Савина Н.В. 
Published: April 2024

В статье предлагается к обсуждению проблема использования отдельного типа искусственного интеллекта – нейросети – в учебной деятельности студентов. Выделены преимущества такого использования, приведены примеры из образовательной практики вузов и школ, показывающие широкий спектр применения нейросетей в обучении студентов и школьников. Вместе с тем, обоснованы риски внедрения искусственного интеллекта, связанные с потерей обучающимися прежде всего важнейших навыков мышления и деятельности. Приведены результаты эмпирического исследования мнений студентов и преподавателей четырех гуманитарных вузов России. Половина опрошенных студентов и преподавателей знают возможности нейросетей, и треть респондентов применяют их в своей деятельности для перевода текстов, подбора литературы и написания научных работ. Вместе с пользой респонденты отмечают и риски применения нейросетей – потерю навыков и способности к аналитическому мышлению, поверхностное обучение и риск потери навыков самостоятельной работы.
he article proposes to discuss the problem of using a neural network as a separate type of artificial intelligence in the educational activities of students. The paper highlights the advantages of its use and gives examples from the educational practice of the universities and schools, showing a wide range of neural networks applications in teaching students and schoolchildren. Also, the risks of introducing artificial intelligence leading to students’ loss of the most important thinking and activity skills, are substantiated in the paper. The article presents the results of the empirical study of the opinions of the students and teachers of four Russian humanities universities. Half of the students and teachers surveyed know the capabilities of neural networks and a third of respondents use them in their activities for translating texts, selecting literature and writing scientific papers. Along with the benefits, the respondents also note the risks of using neural networks as a loss of skills and ability to think analytically, perfunctory training and the risk of losing skills of independent work.
Immersive technologies in education, possible negative aspects of their application
Authors: Мухаметзянов И.Ш. 
Published: April 2024

Проблема исследования. В современном образовании активно используются цифровые технологии – искусственный интеллект и разные форматы виртуальной реальности. Однако основные работы по данной тематике в образовании ориентированы на обоснование педагогической целесообразности их применения, в основном, в профессиональном и дополнительном образовании. Вместе с тем существуют и значимые негативные аспекты для здоровья пользователей при их применении. Нами в рамках данной публикации предприняты попытки описания основных рисков применения этих цифровых технологий, в основном, в общем образовании и в период формирования личности учащегося. Методология. В представленной ниже статье мы рассмотрели общие для всех стран тренды цифровой трансформации и активного использования иммерсивных технологий в образовании. Результаты исследования. Существующие тренды охватывают новые направления подготовки учителей в части принятия и применения иммерсивных технологий, стандартизацию оборудования, вопросы психологической безопасности участников образовательной деятельности при применении цифровых технологий.
The problem of research. Digital technologies are actively used in modern education, for example artificial intelligence and various virtual reality formats. But the main research on this topic in education is focused on the justification of the pedagogical expediency of their application, mainly in professional and additional education. At the same time, there are also significant negative aspects for the health of users caused by application of these technologies. Within the framework of this publication, we have attempted to describe the main risks of using these digital technologies, mainly in primary and secondary education and in the period of formation of a student's personality. Methodology. In the article below, we have reviewed the trends in digital transformation and the active use of immersive technologies in education, which are common to all countries. The results of the study. The existing trends cover new areas of teacher training in terms of the adoption and application of immersive technologies, standardization of equipment, issues of psychological safety of participants in educational activities in conditions of using digital technologies.
Comparison of Compulsory Education of the Republic of Croatia and the Republic of Slovenia
Authors: Krišto Ana , Rajić Višnja 
Published: April 2024

Compulsory education is the basis of formal education, and in countries around the world, it has a different duration and characteristics and most often is related to elementary school. This current study compares compulsory education of the Republic of Croatia and the Republic of Slovenia. In addition to a review of the literature, current applicable laws and regulations, a comparative analysis of national curricula for compulsory education of the Republic of Croatia and the Republic of Slovenia have been made. The study showed that there is a difference in the number of subjects taught in elementary schools in Croatia and Slovenia, as well as in the number of teaching hours of individual subjects. Furthermore, an analysis of six subject areas of primary education that are taught in both countries was made, with respect to content determinants. An analysis of the existing content determinants shows that the same or similar content is taught in both countries, while in only one subject area, further analysis is required. This study provided new insights that can be used to further develop Croatian compulsory education.
Paraneoplastic hypercalcemia in a canine patient with a mandibular salivary carcinoma
Authors: Delgado-Bonet Pablo , Coe Richard , Hammond Gawain J. C. , Wennerdahl Laura A. , McNaught Katie A. 
Published: April 2024

Abstract

OBJECTIVE
To describe a novel presentation of paraneoplastic hypercalcemia caused by a canine salivary carcinoma.

ANIMAL
A 6-year-old intact male Husky with hypercalcemia and a spontaneous salivary carcinoma, stage III.

CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES
The dog presented with polyuria, polydipsia, and hypercalcemia. Physical examination revealed a 37 X 43-mm firm mass in the ventrolateral aspect of the right-hand side of the neck, caudal to the temporomandibular joint. Incisional biopsy was suspicious of metastatic carcinoma to the mandibular lymph node. A full-body CT scan found a large, heterogenous, contrast-enhancing mass on the right ventrolateral neck that appeared to be originating from either the mandibular lymph node or right mandibular salivary gland. Parathyroid hormone–related protein was considered within normal reference intervals, and both parathyroid glands appeared ultrasonographically normal.

TREATMENT AND OUTCOME
The patient was treated with a marginal surgical excision of the mass, without immediate complications. Histopathology confirmed the presence of a salivary carcinoma with narrow margins of excision and invasion of the mandibular lymph node. Twenty-four hours after surgery, ionized calcium returned to normal reference values and clinical signs completely resolved.

CLINICAL RELEVANCE
Hypercalcemia is an urgent pathology with important systemic implications requiring prompt diagnosis and intervention. In this case report, we identify the first salivary carcinoma associated with a paraneoplastic hypercalcemia, including this pathology as a new differential diagnosis. The hypercalcemia resolved with marginal surgical excision, but interestingly the parathyroid hormone–related protein was not overexpressed, meaning that this neoplasia could mediate hypercalcemia by another pathophysiological mechanism.
Dietary Artichoke (Cynara scolymus) Extract Ameliorated the Growth Performance, Humoral Immune Parameters and Resistance Against Aeromonas hydrophila in Goldfish (Carassius auratus)
Authors: Mousavi Shalaleh , Mohammadzadeh Sedigheh , Mood Sara Mehdizadeh , Ahmadifar Ehsan , Sheikhzadeh Najmeh , Kalhor Naser , Moghadam Mohsen Shahriari , Yilmaz Sevdan , Hoseinifar Seyed Hossein , Paolucci Marina 
Published: April 2024

Abstract
This trial investigated the efficacy of artichoke (Cynara scolymus) extract (AE) on the growth performance, immunity, antioxidant parameters, and resistance against Aeromonas hydrophila of goldfish (Carassius auratus). For this purpose, a total number of 470 goldfish with initial weight 5.70±0.2 g were fed with four experimental diets including 0 (T0), 100 (T1), 150 (T2), and 200 (T3) mg kg−1 diet AE for 8 weeks. At the end of feeding trial, growth performances, serum immune parameters, and mucus antioxidant enzymes were measured. Fish were challenged with A. hydrophila, and the antioxidant and immunity-related gene expression were investigated. Based on the results, the highest final weight (FW) and weight gain (WG) were attained in T2 and T3 (P<0.05). Immune factors including ACH50, lysozyme, and total immunoglobulin in T2 and T3 showed the highest values (P<0.05). The expression of GR, IL1
β, TNF
α, HSC70, HSP70, and HSP90
β genes in T1, T2, and T3 were higher than the control (P<0.05). The GST expression was significantly enhanced in T2 (P<0.05). The present study demonstrated that the administration of AE, especially at doses of 150 mg kg−1, could improve the growth, immunity, and antioxidant parameters, as well as enhance disease resistance against A. hydrophila in goldfish.