bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and historical infection of Tacheng tick virus 2: A retrospective investigation
Authors: Jia Yuqing , Zhang Yu , Wu Xuanchen , Dong Zhihui , Xie Songsong , Li Wei , Liu Quan , Lu Xiaobo , Wang Yuanzhi 
Published: June 2024

Background
Tacheng tick virus 2 (TcTV-2) is an emerging tick-borne virus belonging to the genus Uukuvirus in the family Phenuiviridae. Initially isolated in 2019 from a patient in Xinjiang Uygur Autonomous Region (XUAR), northwestern China, who developed fever and headache after a tick bite, TcTV-2 was concurrently molecularly detected in hard ticks across various countries, including China, Kazakhstan, Romania, and Turkey. This study conducted a retrospective epidemiological investigation of TcTV-2 infection.

Methodology
In this retrospective cohort study, we collected samples from 47 tick-bitten patients, 984 herdsmen, 7 Asian badgers, 13 red foxes, and 168 Hyalomma asiaticum tick egg batches. Patients’ samples were primarily analyzed by using high-throughput sequencing, targeting the V3-V4 region of the bacterial 16S rRNA gene and viral cDNA libraries. Typical tick-borne pathogens were further confirmed using RT-PCR and detected in Asian badgers, red foxes and Hy. asiaticum tick egg batches. We also conducted enzyme-linked immunosorbent assay (ELISA) to detected specific IgM and IgG antibodies against TcTV-2 in herdsmen. Phylogenetic analysis was performed to genetically characterize TcTV-2 detected in this study.

Principal findings
TcTV-2 was detected in various samples, including blood, urine, and throat swabs from 12.77% (6/47) tick-bitten patients. It was found in blood samples of 14.29% (1/7) of wild badgers, 7.69% (1/13) of red foxes, and 13.69% (23/168) of Hy. asiaticum egg batches. Furthermore, ELISA results revealed that 9.55% (94/984) of the serum samples (34 from males and 60 from females) were tested positive for TcTV-2-specific IgG, while 2.95% (29/984, 7 males and 22 females) showed positivity for TcTV-2-specific IgM. Additionally, 1.02% (10/984, 4 males and 6 females) of the sera tested positive for both TcTV-2-specific IgM and IgG. Phylogenetic analysis indicated that the TcTV-2 strains detected in this study were genetically similar, regardless of their origin and host species.

Conclusions
Clinical symptoms of TcTV-2 infection in patients are nonspecific, with common symptoms including headache, fever, asthenia, vomiting, myalgia, rash, and meningitis-like signs. TcTV-2 can be detected in blood, urine, and throat swab samples of infected patients. Among local herdsmen, 9.55% tested positive for TcTV-2-specific IgG and 2.95% for TcTV-2-specific IgM. Importantly, TcTV-2 can be transovarially transmitted in Hy. asiaticum ticks, and the Asian badgers and red foxes are potential reservoirs of TcTV-2.
Incidence, characteristics, and risk factors of new liver disorders 3.5 years post COVID-19 pandemic in the Montefiore Health System in Bronx
Authors: Peng Thomas , Duong Katie S. , Lu Justin Y. , Chacko Kristina R. , Henry Sonya , Hou Wei , Fiori Kevin P. , Wang Stephen H. , Duong Tim Q. 
Published: June 2024

Purpose
To determine the incidence of newly diagnosed liver disorders (LD) up to 3.5-year post-acute COVID-19, and risk factors associated with new LD.

Methods
We analyzed 54,699 COVID-19 patients and 1,409,547 non-COVID-19 controls from March-11-2020 to Jan-03-2023. New liver disorders included abnormal liver function tests, advanced liver failure, alcohol and non-alcohol related liver disorders, and cirrhosis. Comparisons were made with ambulatory non-COVID-19 patients and patients hospitalized for other lower respiratory tract infections (LRTI). Demographics, comorbidities, laboratory data, incomes, insurance status, and unmet social needs were tabulated. The primary outcome was new LD at least two weeks following COVID-19 positive test.

Results
Incidence of new LD was not significantly different between COVID-19 and non-COVID-19 cohorts (incidence:1.99% vs 1.90% p>0.05, OR = 1.04[95%CI: 0.92,1.17], p = 0.53). COVID-19 patients with new LD were older, more likely to be Hispanic and had higher prevalence of diabetes, hypertension, chronic kidney disease, and obesity compared to patients without new LD. Hospitalized COVID-19 patients had no elevated risk of LD compared to hospitalized LRTI patients (2.90% vs 2.07%, p>0.05, OR = 1.29[0.98,1.69], p = 0.06). Among COVID-19 patients, those who developed LD had fewer patients with higher incomes (14.18% vs 18.35%, p<0.05) and more with lower incomes (21.72% vs 17.23%, p<0.01), more Medicare and less Medicaid insurance, and more patients with >3 unmet social needs (6.49% vs 2.98%, p<0.001) and fewer with no unmet social needs (76.19% vs 80.42%, p<0.001).

Conclusions
Older age, Hispanic ethnicity, and obesity, but not COVID-19 status, posed increased risk for developing new LD. Lower socioeconomic status was associated with higher incidence of new LD.
Strategic Planning for Post-Earthquake Health Services Continuity: Leveraging Family Healthcare Centers in Istanbul
Authors: Ucal Sari Irem , Adana Mustafa Mert , Atilgan Onurhan 
Published: June 2024

Abstract
Earthquakes, known for their widespread devastation, annually inflict catastrophic consequences globally. Swift and well-structured healthcare responses following earthquakes are pivotal in reducing their impact and mitigating loss of life. However, achieving this demands proactive strategic planning and effective preparedness before disaster strikes. While countries craft disaster response plans, their implementation often proves inadequate in managing the ensuing crisis comprehensively. This study proposes a paradigm shift by advocating for the utilization of widely accessible Family Health Centers (FHCs) as crucial hubs for post-earthquake healthcare continuity. Focused on these community-centric health units, our research delineates a strategic blueprint ensuring uninterrupted health services post an Istanbul earthquake. Integrating SWOT analysis, balanced scorecard, and operations research, this study holistically assesses the current landscape of FHCs and identifies imperative post-earthquake requisites. Insights gleaned from extensive literature review and expert consultations underpin this multifaceted approach.
Objective Feedback: The Views of Pedagogical Study Programme Students
Authors: Stramkale Ligita 
Published: June 2024

Aim. The study aims to determine the views of the pedagogical study programme students about providing objective feedback in the educational process to identify its main characteristics.
Methods. The study uses a mixed research design through the collection and analysis of quantitative and qualitative data within the framework of one study. The study included 82 (n=82) participants studying in part-time bachelor’s and master’s study programmes. The study addresses three research questions: RQ1: At what level do students assess the statements describing the provision of objective feedback? RQ2: What is the difference in students’ views about objective feedback based on the study programme level and their employment? RQ3: What are the main characteristics of objective feedback? SPSS version 22 was used for quantitative data analysis, but the qualitative data were processed using content analysis.
Results. Most respondents agree that objective feedback is significant and motivates students to learn. The study identifies nine main characteristics of objective feedback that were divided into three groups: teacher personality traits, teaching and learning outcomes, and teacher professionalism. The study found that those students who, in parallel with their studies, work part-time in one of the general education institutions rate the competence of teachers in providing objective feedback statistically significantly higher than those students who work in a profession outside the education system or do not work at all.
Conclusion. The findings provide a better understanding of the main characteristics of objective feedback, thereby reducing the subjectivity in assessment.
HOMING AND EGG DISCRIMINATION IN THE WESTERN SLIMY SALAMANDER, PLETHODON ALBAGULA (CAUDATA: PLETHODONTIDAE)
Authors: McCallum Malcolm , Jordan Robyn R. , Milanovich Joseph R. , Trauth Stanley E. 
Published: June 2024

Abstract.— In some species of vertebrates egg brooding is a costly form of parental care. Therefore, misdirection of parental care can significantly lower a female’s fitness. Because of the maternal investment and increased survivorship to offspring from egg guarding, a brooding female should home to her nest site after being displaced a short distance and discriminate between her own eggs and eggs from other females. In this study, we experimentally tested, in the field, alternative hypotheses concerning homing ability and egg discrimination in a population of nesting western slimy salamanders (Plethodon albagula). Fourteen brooding females were displaced 1 m to the left or right of their nest sites (determined randomly) for the homing experiment. Furthermore, brooding females (n = 13) were presented with their own clutches, which were displaced 50 cm to the left or right (determined randomly), and unfamiliar egg clutches at their original nest sites. The females were released at an equal distance from both egg clutches. After 24 hours, 12 displaced females (86%) had returned to their own nest sites and were brooding their egg clutches. Also, after 24 hours, nine test females had returned to their own nest sites and were brooding the unfamiliar egg clutches. No control or test females were present at the other new nest site locations (c2 = 11, df = 1, P-value < 0.001). Therefore, we suggest that brooding female P. albagula do home to their nest sites and exhibit indirect egg discrimination.
DIVISION OF HEREDITARY PROPERTY IN CASE OF HEIR’S BIRTH AFTER TESTATOR’S DEATH
Authors: Лернер С.Д. 
Published: June 2024

В статье рассматриваются основные положения и проблемы института раздела наследного имущества. Автор статьи приводит основные проблемы, связанные с разделом имущества между наследниками, которые родились после смерти наследодателя, в том числе от суррогатной матери, или были зачаты путем экстракорпорального оплодотворения. Автор приходит к выводу о том, что действующее законодательство в области раздела наследного имущества нуждается в дальнейшем совершенствовании.
The article discusses the main provisions and problems of the institution of inherited property division. The author highlights the main problems related to the division of property between heirs who were born after the death of the testator, including from a surrogate mother or were conceived by in vitro fertilization. The author concludes that the existing legislation on the distribution of inherited property needs further improvement.
CRIMINALLY-LEGAL COUNTERMEASURES TO CRIMES IN THE SPHERE OF HOUSING AND COMMUNAL SERVICES: PROBLEMS OF THEORY AND PRACTICE
Authors: Степанова М.А. , Маркова Ю.В. 
Published: June 2024

В силу отсутствия единства взглядов как в теории, так и в судебно-следственной практике, вопросы привлечения к уголовной ответственности за преступления в сфере жилищно-коммунального комплекса, вызывают повышенный интерес. Жилищно-коммунальное хозяйство – это поле нашей ежедневной жизни, наши ежеминутные заботы и вопросы, которые требуют безотлагательного решения. Многие если не знают, то слышали о работе домоуправляющих компаний и товариществ собственников жилья, а также о преступлениях, которые совершаются в этой сфере. Разбираться в нюансах совершенных преступлений необходимо для совершенствования всей системы ЖКХ, а также для эффективной деятельности сотрудников правоохранительных органов. Изучение судебно-следственной практики по уголовным делам о преступлениях в сфере ЖКХ позволяет сделать вывод о том, что действия виновных лиц квалифицируются как мошенничество (ст. 159 УК РФ), присвоение и растрата (ст. 160 УК РФ), кража (ст. 158 УК РФ), злоупотребления полномочиями (ст. 201 УК РФ), злоупотребления должностными полномочиями (ст. 285 УК РФ), нецелевое расходование бюджетных средств (ст. 285.1 УК РФ), получение взятки (ст. 290 УК РФ) и другие. В публикации авторы обращают особое внимание на проблемы, возникающие при решении вопроса о привлечении лиц, использующих свое служебное положение, к уголовной ответственности, что впоследствии затрудняет применение уголовного закона.
Due to a lack of consensus in both theory and judicial practice, issues of criminal responsibility for crimes in the sphere of housing and communal services cause an increased interest. Housing and communal services is a field of our daily life, our constant concerns and issues that require urgent solutions. Many people are aware of the work of house management companies and homeowners' associations and the crimes committed in this area. It is necessary to understand the nuances of the crimes to improve the entire system of housing, as well as provide efficient activities of law enforcement officers. Investigations of judicial practice of criminal cases of housing and communal services allow to conclude that the actions of perpetrators are considered as fraud (article 159 of the Russian Criminal Code), misappropriation and embezzlement (article 160 of the Russian Criminal Code), theft (art. 158 of the Russian Criminal Code), abuse of power (article 201 of the Russian Criminal Code), abuse of official powers (article 285 of the Russian Criminal Code), misappropriation of budgetary funds (article 285.1 of the Russian Criminal Code), taking bribes (article 290 of the Russian Criminal Code) and others. The authors pay special attention to the problems arising from the decision of a question on attraction of individuals using their official position, criminal responsibility, which in consequence hinders the application of criminal law.
ENTREPRENEURIAL ACTIVITY OF MEDICAL ORGANIZATIONS: CHALLENGES AND OPPORTUNITIES IN THE DIGITAL ECONOMY
Authors: Хрячков А.Д. 
Published: June 2024

В статье представлен анализ вызовов и возможностей, с которыми сталкиваются медицинские организации в эпоху цифровой экономики. Рассматриваются проблемы, связанные с необходимостью модернизации технической базы, обеспечением конфиденциальности данных, преодолением цифрового разрыва, адаптацией к изменяющимся потребностям пациентов и соблюдением законодательства о защите данных. Предлагаются стратегии успешного внедрения цифровых технологий и подчеркивается важная роль правового регулирования в развитии предпринимательской деятельности в цифровую эпоху.
The article presents an analysis of the challenges and opportunities faced by medical organizations in the era of the digital economy. The author examines the problems associated with the need to modernize the technical base, ensure data confidentiality, bridge the digital divide, adapt to the changing needs of patients and comply with data protection legislation. The article also suggests strategies for the successful implementation of digital technologies and emphasizes the important role of legal regulation in the development of entrepreneurship in the digital age.
THE RELATIONSHIP BETWEEN SELF-CONTROL AND CYBERBULLYING BEHAVIOR
Authors: Dhian Sulistyowati Arlina , Murtana Agus , Fitria Eri Desviana Ajeng 
Published: June 2024

Introduction: Self-control is an individual’s ability to restrain themselves or direct themselves in a better direction with existing norms. Individuals with high self-control can control themselves well when faced with various difficult situations, such as impolite behavior, harsh words, and even aggressive behavior on social media. Cyberbullying is a negative action carried out by an individual or a group of people by sending text messages, photos, meme images, and videos to someone's social media account to mock, insult, humiliate, discriminate, or persecute that individual. Cyberbullying perpetrators are predominantly teenagers. The current increase in the use of internet technology magnifies the risk of the cyberbullying behavior phenomenon among teenagers. This research aims to determine the relationship between self-control and cyberbullying behavior among students at SMP N 2 Wedi. Methods: This research employed a quantitative design with a cross-sectional study and a correlational approach. Proportionate stratified random sampling was applied as the sampling technique, with a total of 159 responses considering the predetermined inclusion and exclusion criteria. This study incorporated self-control and cyberbullying behavior questionnaires, while Spearman rank correlation was employed for data analysis. Results: the research findings indicate that students have moderate levels of self-control, accounting for 65.4%, and moderate levels of cyberbullying behavior, accounting for 67.3%. The data analysis results show that the p-value was 0.000 < 0.05, with a correlation coefficient value of -0.836. This suggests there is a significantly negative relationship between self-control and cyberbullying among female students at SMP N 2 Wedi. The higher the level of self-control, the lower the cyberbullying behavior. Conclusions: There is a relationship between self-control and cyberbullying behavior.
Implementasi Restitusi terhadap Kekerasan Seksual Kepada Anak Menurut Hukum Positif di Indonesia
Authors: Wardhani Devita Wisnu , Pranawa Burham 
Published: June 2024

<p class="Abstract-Ina-Text">Sistem peradilan pidana Indonesia saat ini telah mengalami banyak perubahan, dengan penekanan yang lebih besar pada pelaksanaan hak-hak terdakwa dan korban kejahatan. proses pelaksanaan undang-undang ini, terdapat beberapa kendala yang masih membutuhkan dukungan hukum dan kepastian hukum. Lalu Pengertian ganti kerugian dalam konteks hak korban adalah pelaku kejahatan membayar ganti rugi kepada korban kejahatan. Selanjutnya yang menjadi metode penelitian yang digunakan penulis dalam artikel ini bersifat analisis deskriptif, yaitu hanya menggambarkan permasalahan secara umum yang diambil dari buku, jurnal maupun media lain yang relevan. Adapun yang akan penulis kaji dalam artikel ini adalah bagaimanakah Implementasi Restitusi Terhadap Kekerasan Seksual Kepada Anak Menurut Hukum Positif di Indonesia. Hasilnya Implementasi Restitusi Terhadap Kekerasan Seksual Kepada Anak Menurut Hukum Positif di Indonesia belum maksimal karena masih terdapat beberapa kendala diantaranya adalah belum adanya undang-undang khusus yang mengatur mengenai restitusi ini sehingga hal tersebut membuat apparat penegak hukum mempunyai tafsir yang berbeda beda.</p>
NaOH Treatment Revolutionizes Strength of Fiber Composites Globally
Authors: Pamungkas Wahyu Aji , Widodo Edi 
Published: June 2024

This study investigates Sansivera fiber-reinforced composite materials treated with 15% NaOH alkaline liquid for different durations using the hand lay-up method. The aim is to determine the optimal treatment duration that enhances the tensile properties of these composites. Results indicate that longer NaOH treatment periods positively impact tensile strength, with the best outcomes observed at 15% treatment for 8 hours. These findings contribute to improving the mechanical performance of Sansivera fiber composites for various industrial applications.

Highlight:

Sansivera composites strengthen with 15% NaOH for 8 hours.
Hand lay-up method enhances industrial applicability.
Optimal treatment duration for Sansivera fibers is highlighted.

Keyword: Sansivera fiber composites, NaOH alkaline treatment, Tensile strength enhancement, Hand lay-up method, Industrial applications
Isolated External Jugular Thrombophlebitis Secondary to Acute Pharyngitis: A Case Report and a Review of the Literature
Authors: Ezeh Uche C. , Tesema Naomi , Hasnie Sukaina , Kahn Philip J. , April Max M. 
Published: June 2024

Abstract

Background
External Jugular Thrombophlebitis (EJT) is a rare clinical phenomenon with few reports in the literature, especially in the pediatric population. This is a report of an unusual case of right-sided EJT in a pediatric patient secondary to acute pharyngitis with sinusitis most prominent on the left side.
Case presentation:
A 13-year-old presented to the emergency department with worsening upper respiratory infectious (URI) symptoms and facial swelling, cough, throat pain, and emesis. The patient had traveled to Switzerland and received amoxicillin for strep throat 6 weeks before this hospitalization. Physical examination revealed nasal purulence, allodynia over the right side of the face without overlying erythema, and oropharyngeal exudate. CT scan revealed left-sided predominate sinusitis and right external jugular vein thrombosis. Blood cultures confirmed the presence of group A streptococcus infection. Treatment included IV antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), IV steroids, and anticoagulation. Follow-up imaging demonstrated improvement in thrombosis, cellulitis, and sinus disease. The patient was discharged on antibiotics for 6 weeks and anticoagulation for 10 weeks. Follow-up imaging at 6 months revealed no EJT, and medications were discontinued.
Conclusions
EJT is a rare condition, and to our knowledge, no reports of EJT with sinusitis most pronounced on the contralateral side have been published. Physicians will benefit from noting clinical signs of EJT such as facial edema, headache, erythema, and palpable neck mass, especially if these symptoms occur with URI symptoms refractory to treatment. The use of anticoagulation is controversial for internal jugular vein thrombosis, and while no guidelines for EJT exist, anticoagulation is likely not necessary save for severe complications.
The applications of circulating cell-free DNA for oral squamous cell carcinoma patients as non-invasive diagnostics of structural variants and fusions
Authors: Frenkel-Morgenstern Milana , Bhattacharya Mahua , Yaniv Dan , Yosef Eyal , Tzelnick Sharon , Detroja Rajesh , D'Souza Dylan , Baum Eliezer Gideon , Mizrachi Aviram , Bachar Gideon 
Published: June 2024

Abstract

Circulating cell-free DNA (cfDNA) has been widely used as a prognostic marker for different cancers. In this study, we used cfDNA from oral squamous cell carcinoma (OSCC) patients to study various correlation factors that could improve the disease early-stage diagnostics and/or prognosis. We found that OSCC patient cfDNA concentration can serve as an indicator of tumor stage, malignancy, and survival prognosis. Deep genome sequencing of cfDNA revealed genomic alterations, such as copy number variations, fusion gene identification, and viral integrations. Copy number variation analysis suggested correlation with amplification and deletion in chromosome 1 at loci 1q, 2q, 3p, 3q and 8q22. Moreover, at these loci, amplification of TP53, PIK3CA and other genes related to keratinization in OSCC patients were observed. In addition, we identified the novel fusion gene, TRMO-TRNT1 ‘chimera’, in seven high-grade tumor samples. The parental genes of this chimera, TRMO and TRNT1, are known to play roles in tRNA modification and DNA repair, respectively. Therefore, our study indicates that liquid biopsy may thus serve as a sensitive tool to study OSCC patient genomic alterations by exploring cfDNA circulating in the plasma, by means of an easy-to-use blood test. Finally, we detected integrations of human papilloma virus, simian virus, and enterovirus in the OSCC samples, that may point to the origins of OSCC.