bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deepwater Horizon Oil Spill: Mental Health Effects on Residents in Heavily Affected Areas
Authors: Osofsky Howard J. , Osofsky Joy D. , Hansel Tonya C. 
Published: December 2011

ABSTRACTBackground:Mental health issues are a significant concern after disasters such as the Deepwater Horizon oil spill in the Gulf of Mexico in 2010. This study was designed to assess the mental health effects on residents of areas of southeastern Louisiana affected by the oil spill.Methods:Telephone and face-to-face interviews were conducted with residents (N = 452) assessing concerns and direct impact.Results:The results show that the greatest effect on mental health related to the extent of disruption to participants' lives, work, family, and social engagement, with increased symptoms of anxiety, depression, and posttraumatic stress. Given the location of the oil spill affecting communities that had been devastated by Hurricane Katrina, results also revealed that losses from Hurricane Katrina were highly associated with negative mental health outcomes. Conversely, the ability to rebound after adversity and place satisfaction were highly associated with better mental health outcomes.Conclusions:Enhanced understanding of mental health effects after the Deepwater Horizon oil spill will help in determining directions for much-needed mental health services after the disaster and in contributing to the knowledge of complex traumatization and the ability to rebound after adversity.(Disaster Med Public Health Preparedness. 2011;5:280–286)
Genome‐wide SNP genotyping identifies the Stereocilin (STRC) gene as a major contributor to pediatric bilateral sensorineural hearing impairment
Authors: Francey Lauren J. , Conlin Laura K. , Kadesch Hanna E. , Clark Dinah , Berrodin Donna , Sun Yi , Glessner Joe , Hakonarson Hakon , Jalas Chaim , Landau Chaim , Spinner Nancy B. , Kenna Margaret , Sagi Michal , Rehm Heidi L. , Krantz Ian D. 
Published: December 2011

AbstractHearing loss is the most prevalent sensory perception deficit in humans, affecting 1/500 newborns, can be syndromic or nonsyndromic and is genetically heterogeneous. Nearly 80% of inherited nonsyndromic bilateral sensorineural hearing loss (NBSNHI) is autosomal recessive. Although many causal genes have been identified, most are minor contributors, except for GJB2, which accounts for nearly 50% of all recessive cases of severe to profound congenital NBSNHI in some populations. More than 60% of children with a NBSNHI do not have an identifiable genetic cause. To identify genetic contributors, we genotyped 659 GJB2 mutation negative pediatric probands with NBSNHI and assayed for copy number variants (CNVs). After identifying 8 mild‐moderate NBSNHI probands with a Chr15q15.3 deletion encompassing the Stereocilin (STRC) gene amongst this cohort, sequencing of STRC was undertaken in these probands as well as 50 probands and 14 siblings with mild‐moderate NBSNHI and 40 probands with moderately severe‐profound NBSNHI who were GJB2 mutation negative. The existence of a STRC pseudogene that is 99.6% homologous to the STRC coding region has made the sequencing interpretation complicated. We identified 7/50 probands in the mild‐moderate cohort to have biallelic alterations in STRC, not including the 8 previously identified deletions. We also identified 2/40 probands to have biallelic alterations in the moderately severe‐profound NBSNHI cohort, notably no large deletions in combination with another variant were found in this cohort. The data suggest that STRC may be a common contributor to NBSNHI among GJB2 mutation negative probands, especially in those with mild to moderate hearing impairment. © 2011 Wiley Periodicals, Inc.
Reinforcement of soy polyol‐based rigid polyurethane foams by cellulose microfibers and nanoclays
Authors: Zhu Min , Bandyopadhyay‐Ghosh Sanchita , Khazabi Mustafa , Cai Hui , Correa Carlos , Sain Mohini 
Published: December 2011

AbstractWater‐blown rigid polyurethane foams from soy‐based polyol were prepared and their structure–property correlations investigated. Cellulose microfibers and nanoclays were added to the formulations to investigate their effect on morphology, mechanical, and thermal properties of polyurethane foams. Physical properties of foams, including density and compressive strength, were determined. The cellular morphologies of foams were analyzed by SEM and X‐ray micro‐CT and revealed that incorporation of microfibers and nanoclays into foam altered the cellular structure of the foams. Average cell size decreased, cell size distribution narrowed and number fractions of small cells increased with the incorporation of microfibers and nanoclays into the foam, thereby altering the foam mechanical properties. The morphology and properties of nanoclay reinforced polyurethane foams were also found to be dependent on the functional groups of the organic modifiers. Results showed that the compressive strengths of rigid foams were increased by addition of cellulose microfibers or nanoclays into the foams. Thermogravimetric analysis (TGA) was used to characterize the thermal decomposition properties of the foams. The thermal decomposition behavior of all soy‐based polyurethane foams was a three‐step process and while the addition of cellulose microfibers delayed the onset of degradation, incorporation of nanoclays seemed to have no significant influence on the thermal degradation properties of the foams as compared to the foams without reinforcements. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Morphology and mechanical properties of nanocomposites of cellulose acetate and organic montmorillonite prepared with different plasticizers
Authors: de Lima Juliana Aristéia , Augusto Pinotti Caio , Felisberti Maria Isabel , do Carmo Gonçalves Maria 
Published: December 2011

AbstractNanocomposites of cellulose acetate and an organically modified montmorillonite (CA/MMTO) were prepared by melt intercalation in a twin‐screw extruder, using two different plasticizers: di‐octyl phthalate (DOP) and triethyl citrate (TEC). The influence of plasticizer type and the organoclay added to the structure, the morphology, and the thermal properties of the nanocomposites was investigated. XRD and SAXS results indicated a significant CA or/and plasticizer intercalation in the clay gallery for the CA/MMTO nanocomposites. In addition, the images obtained by TEM show that the morphology of CA/MMTO nanocomposites is made up of intercalated and exfoliated silicate layers. The glass transition temperature (Tg) of CA with DOP or TEC decreased in at almost same value, which shows the characteristics of both additives as plasticizers for cellulose acetate chains. Tensile tests indicate that the nanocomposites with either of the two plasticizers presented the same performance with respect to material properties. The results demonstrated that, for some applications, TEC is an useful alternative to plasticize CA in order to substitute DOP, a non eco‐friendly plasticizer. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
High performance PEEK/AlN micro‐ and nanocomposites for tribological applications
Authors: Goyal R. K. , Tiwari A. N. , Negi Y. S. 
Published: December 2011

AbstractThe tribological properties of poly(ether–ether–ketone) (PEEK)/aluminum nitride (AlN) composites reinforced with micro‐ and nano‐AlN particles were evaluated under dry sliding conditions. The wear resistance of pure PEEK is 10‐fold higher than mild steel. It was further improved by 2‐fold at 20 wt % micro‐AlN and by more than 4‐fold at 30 wt % nano‐AlN composite compared with pure PEEK. The improvement in wear resistance was attributed to a thin and coherent transfer film. However, it was deteriorated on further increasing micro‐AlN. The coefficient of friction of the composites was increased. Scanning electron microscopy and optical microscopy of worn surfaces and transfer films have been explained in detail. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Using an elaboration likelihood approach to better understand the persuasiveness of website privacy assurance cues for online consumers
Authors: Lowry Paul Benjamin , Moody Greg , Vance Anthony , Jensen Matthew , Jenkins Jeff , Wells Taylor 
Published: December 2011

AbstractPrivacy concerns can greatly hinder consumers' intentions to interact with a website. The success of a website therefore depends on its ability to improve consumers' perceptions of privacy assurance. Seals and assurance statements are mechanisms often used to increase this assurance; however, the findings of the extant literature regarding the effectiveness of these tools are mixed. We propose a model based on the elaboration likelihood model (ELM) that explains conditions under which privacy assurance is more or less effective, clarifying the contradictory findings in previous literature. We test our model in a free‐simulation online experiment, and the results of the analysis indicate that the inclusion of assurance statements and the combination, understanding, and assurance of seals influence privacy assurance. Privacy assurance is most effective when seals and statements are accompanied by the peripheral cues of website quality and brand image and when counter‐argumentation—through transaction risk—is minimized. Importantly, we show ELM to be an appropriate theoretical lens to explain the equivocal results in the literature. Finally, we suggest theoretical and practical implications.
Sr–Mg Mixed Oxides as Biodiesel Production Catalysts
Authors: Faungnawakij Kajornsak , Yoosuk Boonyawan , Namuangruk Supawadee , Krasae Pawnprapa , Viriya‐empikul Nawin , Puttasawat Buppa 
Published: December 2011

AbstractThe Sr–Mg basic catalysts were developed for biodiesel production through transesterification of palm oil with methanol. The evidence for synergistic effects between active Sr and Mg species was clearly demonstrated by transesterification tests over a series of Sr–Mg catalysts with varied Sr‐to‐Mg molar ratios. The catalyst properties were characterised by means of temperature‐programmed desorption of CO2 (CO2‐TPD), N2 sorption, XRD, SEM and TEM experiments. The super strong basic site was formed in Sr–Mg catalysts through a partial solid state reaction induced by thermal treatment at 600 °C. The new basic site, together with the original basic site from SrO (average basic site density=757 μmol m−2), effectively catalysed a transesterification reaction at mild conditions. Biodiesel containing 96 % methyl esters was obtained at reaction conditions of 75 min, 60 °C, 0.1 MPa, 3 wt. % catalyst loading and a methanol‐to‐oil ratio of 6:1, and the catalyst exhibited good reusability. Improved surface areas and porosities were also achieved compared to the unsupported SrO. Density functional theory (DFT) calculations of methylpropanoate adsorption on SrO, MgO and Sr/MgO showed that the adsorption energies of all adsorbate–surface complexes corresponded well with the experimental catalytic activity, which increased in the order MgO<SrO<Sr/MgO.
The Inhibition of Liposaccharide Heptosyltransferase WaaC with Multivalent Glycosylated Fullerenes: A New Mode of Glycosyltransferase Inhibition
Authors: Durka Maxime , Buffet Kevin , Iehl Julien , Holler Michel , Nierengarten Jean‐François , Vincent Stéphane P. 
Published: December 2011

Abstractl,d‐Heptosides (L‐glycero‐D‐manno‐heptopyranoses) are found in important bacterial glycolipids such as lipopolysaccharide (LPS), the biosynthesis of which is targeted for the development of novel antibacterial agents. This work describes the synthesis of a series of fullerene hexa‐adducts bearing 12 copies of peripheral sugars displaying the mannopyranose core structure of bacterial l,d‐heptoside. The multimers were assembled through an efficient copper‐catalyzed alkyne–azide cycloaddition reaction as the final step. The final fullerene sugar balls were assayed as inhibitors of heptosyltransferase WaaC, the glycosyltransferase catalyzing the incorporation of the first L‐heptose into LPS. Interestingly, the inhibition of the final molecules was found in the low micromolar range (IC50=7–45 μM), whereas the corresponding monomeric glycosides displayed high micromolar to low millimolar inhibition levels (IC50 always above 400 μM). When evaluated on a “per‐sugar” basis, these inhibition data showed that, in each case, the average affinity of a single glycoside of the fullerenes towards WaaC was significantly enhanced when displayed as a multimer, thus demonstrating an unexpected multivalent effect. To date, such a multivalent mode of inhibition had never been evidenced with glycosyltransferases.
Guest‐Responsive Covalent Frameworks by the Cross‐Linking of Liquid‐Crystalline Salts: Tuning of Lattice Flexibility by the Design of Polymerizable Units
Authors: Ishida Yasuhiro , Sakata Hiroaki , Achalkumar Ammathnadu S. , Yamada Kuniyo , Matsuoka Yuki , Iwahashi Nobutaka , Amano Sayaka , Saigo Kazuhiko 
Published: December 2011

AbstractCross‐linked polymers prepared by the in‐situ polymerization of liquid‐crystalline salts were found to work as solid‐state hosts with a flexible framework. As a component of such hosts, four kinds of polymerizable amphiphilic carboxylic acids bearing alkyl chains with acryloyloxy (A), dienyl (D), and/or nonreactive (N) chain ends (monomeric carboxylic acids; MAAA, MANA, MDDD, and MDND) were used. The carboxylic acids were mixed with an equimolar amount of a template unit, (1R,2S)‐norephedrine (guest amine; GRS), to form the corresponding salts. Every salt exhibited a rectangular columnar LC phase at room temperature, which was successfully polymerized by 60Co γ‐ray‐induced polymerization without serious structural disordering to afford the salt of cross‐linked carboxylic acid (polymeric carboxylic acid; PAAA, PANA, PDDD, and PDND) with GRS. Owing to the noncovalency of the interactions between the polymer framework P and the template GRS, the cross‐linked polymers could reversibly release and capture a meaningful amount of GRS. In response to the desorption and adsorption of GRS, the cross‐linked polymers dramatically switched their nanoscale structural order. A systematic comparison of the polymers revealed that the choice of polymerizable groups has a significant influence on the properties of the resultant polymer frameworks as solid‐state hosts. Among these polymers, PDDD was found to be an excellent solid‐state host, in terms of guest‐releasing/capturing ability, guest‐recognition ability, durability to repetitive usage, and unique structural switching mode.
Interplay between Defect Structure and Catalytic Activity in the Mo10−xVxOy Mixed‐Oxide System
Authors: Jakes Peter , Blickhan Nina , Jekewitz Tim , Drochner Alfons , Vogel Herbert , Fuess Hartmut , Eichel Rüdiger‐A. 
Published: December 2011

AbstractThe Mo10−xVxOy solid‐solution systems (0≤x≤10) were studied by electron paramagnetic resonance spectroscopy. The results show the existence of paramagnetic vanadyl VO2+ species, whose concentration becomes maximal for Mo5V5Oy. A quantitative analysis of the [VO2+] concentration as a function of the Mo/V ratio allows it to characterize the prevailing defect chemistry in the Mo10−xVxOy system. In this respect, the semi‐conducting properties of Mo10−xVxOy are p‐type in an interval of Mo9V1Oy–Mo5V5Oy and switch into n‐type because of the conduction electrons in a composition range of Mo5V5Oy–Mo1V9Oy. Highest catalytic activity is obtained when vanadium acts as an acceptor center and oxygen vacancies ${\left( {\upsilon _{\rm{O}}^{ \bullet \bullet } } \right)}$ are formed for reasons of charge compensation. In addition to the surface, ${\upsilon _{\rm{O}}^{ \bullet \bullet } }$ and VO2+ centers in the bulk have to be considered too for heterogeneous catalysis.
Oxidative Addition of the CαCβ Bond in β‐O‐4 Linkage of Lignin to Transition Metals Using a Relativistic Pseudopotential‐Based ccCA‐ONIOM Method
Authors: Oyedepo Gbenga A. , Wilson Angela K. 
Published: December 2011

AbstractA multi‐level multi‐layer QM/QM method, the relativistic pseudopotential correlation‐consistent composite approach within an ONIOM framework (rp‐ccCA‐ONIOM), was applied to study the oxidative addition of the CαCβ bond in an archetypal arylglycerol β‐aryl ether (β‐O‐4 linkage) substructure of lignin to Ni, Cu, Pd and Pt transition metal atoms. The chemically active high‐level layer is treated using the relativistic pseudopotential correlation‐consistent composite approach (rp‐ccCA), an efficient methodology designed to reproduce an accuracy that would be obtained using the more computationally demanding CCSD(T)/aug‐cc‐pCV∞Z‐PP, albeit at a significantly reduced computational cost, while the low‐level layer is computed using B3LYP/cc‐pVTZ. The thermodynamic and kinetic feasibilities of the model reactions are reported in terms of enthalpies of reactions at 298 K (ΔH°298) and activation energies (ΔH‐act). The results obtained from the rp‐ccCA:B3LYP hybrid method are compared to the corresponding values using CCSD(T) and several density functionals including B3LYP, M06, M06 L, B2PLYP, mPWPLYP and B2GP‐PLYP. The energetics of the oxidative addition of CC bond in ethane to Ni, Cu, Pd and Pt atoms are also reported to demonstrate that the rp‐ccCA method effectively reproduces the accuracy of the CCSD(T)/aug‐cc‐pCV∞Z method. Our results show that in the catalytic activation of the CαCβ bond of β‐O‐4, the use of platinum metal catalysts will lead to the most thermodynamically favored reaction with the lowest activation barrier.
ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus
Authors: Tríbulo Celeste , Guadalupe Barrionuevo María , Agüero Tristán H. , Sánchez Sara S. , Calcaterra Nora B. , Aybar Manuel J. 
Published: December 2011

AbstractBackground: It has been established in several models that the p63 gene has an important role in the development of the epidermis and its derivatives. In Xenopus, only the ΔNp63 isoform of this gene has been cloned and its role during epidermal development remains unknown. Results: In this work, we showed that ΔNp63 is expressed in the nonneural ectoderm since the gastrula stage and that it is regulated by the bone morphogenetic protein 4 (BMP4) signaling pathway. Our in vivo and in vitro experiments demonstrated that ΔNp63 is required in the earliest inductive steps of epidermal development. The overexpression of ΔNp63 caused an increase in epidermal markers with a suppression of neural induction while the blocking of ΔNp63 led to the opposite results. Finally, we found that ΔNp63 acts as an anti‐apoptotic gene, regulating the transcription of some apoptotic and anti‐apoptotic factors. Conclusion: The results suggest that ΔNp63 is an essential gene in early epidermal specification under the control of BMP4. Developmental Dynamics 241:257–269, 2012. © 2011 Wiley Periodicals, Inc.
Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system
Authors: Douglas Nataki C. , Heng Kathleen , Sauer Mark V. , Papaioannou Virginia E. 
Published: December 2011

AbstractBackground: Tbx2, Tbx3, Tbx4, and Tbx5, members of the Tbx2 subfamily of T‐box transcription factor genes, are important for many aspects of embryonic development and mutations in some human TBX2 subfamily genes cause developmental syndromes. In addition, TBX2 and TBX3 are overexpressed in a variety of cancers, including reproductive system cancers. This study characterizes the expression of Tbx2 subfamily genes during development of the reproductive system. Results: We show that these genes are expressed in both the internal and external reproductive systems. Tbx2 is expressed in gonads and genital ducts, the Wolffian and Müllerian ducts, while Tbx3 is only expressed in genital ducts. Tbx4 is expressed in embryonic and postnatal germ cells. All four genes are expressed in mesenchyme in external genitalia, with Tbx3 and Tbx5 expression in the epithelium as well. Conclusion: This study lays the foundation for investigation of functional requirements for Tbx2 subfamily genes in development of the mammalian reproductive system. Developmental Dynamics 241:365–375, 2012. © 2011 Wiley Periodicals, Inc.
Fibulin‐1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation
Authors: Cooley Marion A. , Fresco Victor M. , Dorlon Margaret E. , Twal Waleed O. , Lee Nathan V. , Barth Jeremy L. , Kern Christine B. , Iruela‐Arispe M. Luisa , Argraves W. Scott 
Published: December 2011

AbstractBackground: Trabeculation is an integral component of cardiac ventricular morphogenesis and is dependent on the matrix metalloproteinase, ADAMTS1. A substrate of ADAMTS1 is the proteoglycan versican which is expressed in the developing ventricle and which has been implicated in trabeculation. Fibulin‐1 is a versican and ADAMTS1‐binding extracellular matrix protein required for ventricular morphogenesis. Here we investigated the involvement of fibulin‐1 in ADAMTS1‐mediated cleavage of versican in vitro, and the involvement of fibulin‐1 in versican cleavage in ventricular morphogenesis. Results: We show that fibulin‐1 is a cofactor for ADAMTS1‐dependent in vitro cleavage of versican V1, yielding a 70‐kDa amino‐terminal fragment. Furthermore, fibulin‐1‐deficiency in mice was found to cause a significant reduction (>90%) in ventricular levels of the 70‐kDa versican V1 cleavage product and a 2‐fold increase in trabecular cardiomyocyte proliferation. Decreased versican V1 cleavage and augmented trabecular cardiomyocyte proliferation in fibulin‐1 null hearts is accompanied by increased ventricular activation of ErbB2 and Erk1/2. By contrast, versican deficiency was found to lead to decreased cardiomyocyte proliferation and reduced ventricular trabeculation. Conclusion: We conclude that fibulin‐1 regulates versican‐dependent events in ventricular morphogenesis by promoting ADAMTS1 cleavage of versican leading to suppression of trabecular cardiomyocyte proliferation mediated by the ErbB2‐Map kinase pathway. Developmental Dynamics 241:303–314, 2012. © 2011 Wiley Periodicals, Inc.
Effects of climate change on evapotranspiration and soil water availability in Norway spruce forests in southern Finland: an ecosystem model based approach
Authors: Ge Zhen‐Ming , Kellomäki Seppo , Zhou Xiao , Wang Kai‐Yun , Peltola Heli , Väisänen Hannu , Strandman Harri 
Published: December 2011

ABSTRACTNorway spruce (Picea abies) is sensitive to decreases in soil water availability. In this study, we simulated how the climate change may influence the hydrological processes with impacts on the growth of Norway spruce in three sites located in southern Finland (61oN). The sites differed from each other in regard to the climate and soil water conditions; however, the initial structure of the tree stands was similar. Under the current climate, the canopy surface evaporation (Ec) increased, whereas the transpiration (Et) remained at a constant rate over the simulation period, as the seedlings in the initial stand grew to full maturity. Under the changing climate, on average, the cumulative of Ec and Eg (evaporation from soil surface) were 16% and 14% higher than those under the current climate, respectively, whereas the cumulative Et was 12% lower. The leaf area index (L) increased constantly on the sites with high (SH) and medium (SM) soil moisture, unlike on the site with low (SL) soil moisture. The canopy conductance (gcs) declined rapidly and earlier on the site SL, which implied the acclimation of stomatal behaviour to drought. The increasing water loss through evaporation decreased the water infiltration into the soil profile, resulting in an increasing soil water deficit (Wd), especially on the site SL. It also occurred earlier in all three sites under the changing climate. It was predicted that climate change will create a suboptimal environment for Norway spruce in southern Finland, particularly on the upland sites with lower groundwater table. Copyright © 2011 John Wiley & Sons, Ltd.