bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of the CsCENH3 protein and centromeric DNA profiles reveal the structures of centromeres in cucumber
Authors: Wang Yi , Zhou Fang , Li Yangang , Yu Xiaqing , Wang Yuhui , Zhao Qinzheng , Feng Xianbo , Chen Jinfeng , Lou Qunfeng 
Published: May 2024

Abstract
Centromeres in eukaryotes mediate the accurate segregation of chromosomes during cell division. They serve as essential functional units of chromosomes and play a core role in the process of genome evolution. Centromeres are composed of satellite repeats and highly repetitive centromeric retrotransposons (CRs), which vary greatly even among closely related species. Cucumber (Cucumis sativus) is a globally cultivated and economically important vegetable and the only species in the Cucumis genus with seven pairs of chromosomes. Therefore, studying the centromeres of the Cucumis subgenus may yield valuable insights into its genome structure and evolution. Using chromatin immunoprecipitation (ChIP) techniques, we isolated centromeric DNA from cucumber reference line 9930. Our investigation into cucumber centromeres uncovered the centromeric satellite sequence, designated as CentCs, and the prevalence of Ty1/Copia long terminal repeat retrotransposons. In addition, active genes were identified in the CsCENH3 nucleosome regions with low transcription levels. To the best of our knowledge, this is the first time that characterization of centromeres has been achieved in cucumber. Meanwhile, our results on the distribution of CentCs and CsCRs in the subgenus Cucumis indicate that the content of centromeric repeats in the wild variants was significantly reduced compared with the cultivated cucumber. The results provide evidence for centromeric DNA amplification that occurred during the domestication process from wild to cultivated cucumber. Furthermore, these findings may offer new information for enhancing our understanding of phylogenetic relationships in the Cucumis genus.
Who Manages Menstrual Health? The Untapped Potential of the Right to Health to Support a Comprehensive Right to Menstrual Health beyond Menstrual Hygiene Management
Authors: Brassart Olsen Céline 
Published: May 2024

Abstract
For the 1.8 billion people who menstruate every month globally, menstruation is not always just synonymous with blood loss. As such, many also experience premenstrual conditions such as dysmenorrhea (period pain), limited access to health care and/or menstrual stigma. Yet, so far, laws have mostly focused on menstrual hygiene management (MHM), particularly menstrual products provision. Despite MHM’s success, scholars have criticized its narrow focus on products at the expense of a more comprehensive definition of menstrual health, which recognises the menstrual cycle, and includes menarche and menopause. Meanwhile, global institutions have been shifting their focus from menstrual hygiene to menstrual health, and have framed the latter as a health and human rights issue. However, so far, the Committee on Economic Social and Cultural Rights and the Special Rapporteur on the Right to Health have mostly remained silent on the topic of menstrual health. The article argues that these mechanisms should conceptualize a right to menstrual health, which promotes menstruators’ rights to health literacy, agency, participation, culture and increased scrutiny of the menstrual products industry.
Physiology Evolves Convergently but Lags Behind Warming in Cities
Authors: Diamond Sarah E , Kolaske Logan R , Martin Ryan A 
Published: May 2024

Synopsis
Cities, through the generation of urban heat islands, provide a venue for exploring contemporary convergent evolution to climatic warming. We quantified how repeatable the evolution of heat tolerance, cold tolerance, and body size was among diverse lineages in response to urban heat islands. Our study revealed significant shifts toward higher heat tolerance and diminished cold tolerance among urban populations. We further found that the magnitude of trait divergence was significantly and positively associated with the magnitude of the urban heat island, suggesting that temperature played a major role in the observed divergence in thermal tolerance. Despite these trends, the magnitude of trait responses lagged behind environmental warming. Heat tolerance responses exhibited a deficit of 0.84°C for every 1°C increase in warming, suggesting limits on adaptive evolution and consequent adaptational lags. Other moderators were predictive of greater divergence in heat tolerance, including lower baseline tolerance and greater divergence in body size. Although terrestrial species did not exhibit systematic shifts toward larger or smaller body size, aquatic species exhibited significant shifts toward smaller body size in urban habitats. Our study demonstrates how cities can be used to address long-standing questions in evolutionary biology regarding the repeatability of evolution. Importantly, this work also shows how cities can be used as forecasting tools by quantifying adaptational lags and by developing trait-based associations with responses to contemporary warming.
Follicular fluid meiosis-activating sterol prevents porcine ovarian granulosa cells from hypoxia-induced apoptosis via inhibiting STAT4 expression
Authors: Liu Zhaojun , Li Chengyu , Chen Qianqian , Bai Chenyu , Wu Gang , Fu Chen , He Tong , Shen Ming , Feng Chungang , Liu Honglin 
Published: May 2024

Abstract
Follicular fluid meiosis-activating sterol (FF-MAS) is a small molecule compound found in FF, named for its ability to induce oocyte resumption of meiosis. Granulosa cells (GCs) within the follicle are typically located in a hypoxic environment under physiologic conditions due to limited vascular distribution. Previous research suggests that hypoxia-induced cell cycle arrest and apoptosis in GCs may be crucial triggering factors in porcine follicular atresia. However, the impact of FF-MAS on GCs within follicles has not been explored so far. In this study, we uncovered a novel role of FF-MAS in facilitating GC survival under hypoxic conditions by inhibiting STAT4 expression. We found that STAT4 expression was upregulated in porcine GCs exposed to 1% O2. Both gain and loss of function assays confirmed that STAT4 was required for cell apoptosis under hypoxia conditions, and that the GC apoptosis caused by hypoxia was markedly attenuated following FF-MAS treatment through inhibition of STAT4 expression. Correlation analysis in vivo revealed that GC apoptosis was associated with increased STAT4 expression, while the FF-MAS content in follicular fluid was negatively correlated with STAT4 mRNA levels and cell apoptosis. These findings elucidate a novel role of FF-MAS-mediated protection of GCs by inhibiting STAT4 expression under hypoxia, which might contribute to the mechanistic understanding of follicular development.
Hemolymph metabolism of black soldier fly (Diptera: Stratiomyidae), response to different supplemental fungi
Authors: Kannan Mani , Vitenberg Tzach , Schweitzer Ron , Opatovsky Itai 
Published: May 2024

Abstract
The black soldier fly, Hermetia illucens L. (Diptera: Stratiomyidae), is commonly used for organic waste recycling and animal feed production. However, the often inadequate nutrients in organic waste necessitate nutritional enhancement of black soldier fly larvae, e.g., by fungal supplementation of its diet. We investigated the amino acid composition of two fungi, Candida tropicalis (Castell.) Berkhout (Saccharomycetales: Saccharomycetaceae) and Pichia kudriavzevii Boidin, Pignal & Besson (Saccharomycetales: Pichiaceae), from the black soldier fly gut, and commercial baker’s yeast, Saccharomyces cerevisiae Meyen ex E.C. Hansen (Saccharomycetales: Saccharomycetaceae), and their effects on larval growth and hemolymph metabolites in fifth-instar black soldier fly larvae. Liquid chromatography–mass spectrometry was used to study the effect of fungal metabolites on black soldier fly larval metabolism. Amino acid analysis revealed significant variation among the fungi. Fungal supplementation led to increased larval body mass and differential metabolite accumulation. The three fungal species caused distinct metabolic changes, with each over-accumulating and down-accumulating various metabolites. We identified significant alteration of histidine metabolism, aminoacyl-tRNA biosynthesis, and glycerophospholipid metabolism in BSF larvae treated with C. tropicalis. Treatment with P. kudriavzevii affected histidine metabolism and citrate cycle metabolites, while both P. kudriavzevii and S. cerevisiae treatments impacted tyrosine metabolism. Treatment with S. cerevisiae resulted in down-accumulation of metabolites related to glycine, serine, and threonine metabolism. This study suggests that adding fungi to the larval diet significantly affects black soldier fly larval metabolomics. Further research is needed to understand how individual amino acids and their metabolites contributed by fungi affect black soldier fly larval physiology, growth, and development, to elucidate the interaction between fungal nutrients and black soldier fly physiology.
The first record of an established population of Amblyomma maculatum (Acari: Ixodidae) in New Jersey, USA
Authors: Musnoff Brandon L , Cuadera Mervin Keith Q , Birney Matthew R , Zipper Lara , Nicholson William , Ayres Bryan , Cervantes Kim , Woell Dana , Occi James L 
Published: May 2024

Abstract
Amblyomma maculatum Koch, the Gulf Coast tick, is expanding northward from its original range in the southeastern United States. In 2013, its most northern collection was in Delaware. Amblyomma maculatum has since been found in Connecticut, Illinois, and New York. It is the vector of the human pathogen Rickettsia parkeri, the causative agent of R. parkeri rickettsiosis. We report the first finding of an established population of A. maculatum in Salem County, NJ, with a R. parkeri infection prevalence rate of 23.8%. Our finding of A. maculatum is consistent with other recent findings in the northeastern United States in that specimens were found in open areas devoid of tree canopy. This discovery demonstrates the importance of tick surveillance in order to identify expanding tick populations and the pathogens they may transmit.
Bridging perceived organizational support with learning motivation and work engagement: the mediating role of focus on opportunity
Authors: Mori Koji , Adi Nuri Purwito , Odagami Kiminori , Nagata Tomohisa 
Published: May 2024

AbstractObjectivesPerceived organizational support (POS) represents the extent to which employees believe their organization values their contributions and well-being. Although higher POS is associated with increased work engagement and learning motivation, the intricacies of this relationship, especially the mediation by occupational future time perspective (OFTP), are not well understood.MethodsWe conducted an online survey of 2046 working individuals aged 20-69 to assess the relationships between POS and 2 outcome variables, learning goal orientation (LGO) and work engagement, with multiple regression analyses for all ages and in the younger age group (under 45). Then, the mediating effects of focus on opportunity (FOO)—a primary component of OFTP—on these relationships were examined.ResultsOf 2046 participants, 887 were younger than 45 years. Younger participants, predominantly more educated and inclined toward professional jobs, exhibited higher LGO but lower work engagement compared with their older counterparts. POS showed positive correlations with LGO, and FOO significantly mediated the relationship, especially in the young group. Furthermore, a positive relationship between POS and work engagement was noted, with FOO as a partial mediator.ConclusionsPOS correlates positively with both LGO and work engagement across various age demographics, with FOO critically mediating this relationship. To enhance employee engagement and learning motivation, organizations should emphasize bolstering both POS and FOO.
Ethical Dilemmas Faced by Military Health Personnel During High-Intensity Conflict: The Crucial Issue of Triage
Authors: Gignoux-Froment Frédérique , Martinez Thibault , Derely Jean , Turc Jean , Corcostegui Simon-Pierre , Derkenne Clément , Peigne Vincent , Trousselard Marion , Bazin Angèle , Lamblin Antoine 
Published: May 2024

ABSTRACT
Russia’s invasion of Ukraine has triggered the biggest conflict in Europe since the Second World War. It has forced countries to prepare for engagement on a massive scale, namely, a high-intensity war between nation states. A potential massive influx of wounded personnel risks saturating logistical supply chains and requires changes to not only medical care but also a paradigm shift. In this context, the principle of distributive justice is key. The aim is to save as many lives as possible through triage, which consists in “doing the greatest good for the greatest number.” This idea is fundamental, as an emergency that has passed is no longer an emergency. However, international texts and treaties not only underline that the sole criterion for triage is clinical severity, but they also fail to take into account the patient’s status (civilian, friend, and foe). In a high-intensity warfare situation, these texts, and the medical-surgical triage criteria they provide are insufficient, as caregivers may be required to make decisions based on the status of the patient. The need to make such choices could cause psychological suffering among military caregivers, as individuals are recurrently faced with difficult ethical dilemmas. One way to prevent this happening is to provide predeployment training in wartime medical ethics. The latter would include both instruction in international humanitarian law and practical simulations of clinical situations where the person is faced with an ethical dilemma.
Dark Energy Survey Year 6 results: Intra-cluster light from redshift 0.2 to 0.5
Authors: Zhang Yuanyuan , Golden-Marx Jesse B , Ogando Ricardo L C , Yanny Brian , Rykoff Eli S , Allam Sahar , Aguena M , Bacon D , Bocquet S , Brooks D , Carnero Rosell A , Carretero J , Cheng T -Y , Conselice C , Costanzi M , da Costa L N , Pereira M E S , Davis T M , Desai S , Diehl H T , Doel P , Ferrero I , Flaugher B , Frieman J , Gruen D , Gruendl R A , Hinton S R , Hollowood D L , Honscheid K , James D J , Jeltema T , Kuehn K , Kuropatkin N , Lahav O , Lee S , Lima M , Mena-Fernández J , Miquel R , Palmese A , Pieres A , Plazas Malagón A A , Romer A K , Sanchez E , Smith M , Suchyta E , Tarle G , To C , Tucker D L , Weaverdyck N ,   DES Collaboration
Published: May 2024

ABSTRACT
Using the full 6 years of imaging data from the Dark Energy Survey, we study the surface brightness profiles of galaxy cluster central galaxies and intra-cluster light. We apply a ‘stacking’ method to over 4000 galaxy clusters identified by the redMaPPer cluster finder in the redshift range of 0.2−0.5. This yields high-signal-to-noise circularly averaged profile measurements of the central galaxy and intra-cluster light out to 1 Mpc from the cluster centre. Using redMaPPer richness as a cluster mass indicator, we find that the brightness of the intra-cluster light has a strong mass dependence throughout the 0.2−0.5 redshift range, and this dependence grows stronger at a larger radius. In terms of redshift evolution, we find some evidence that the central galaxy, as well as the diffuse light within the transition region between the cluster central galaxy and intra-cluster light within 80 kpc from the centre, may be growing over time. At larger radii, more than 80 kpc away from the cluster centre, we do not detect evidence of additional redshift evolution beyond the cluster mass dependence, consistent with the findings from the IllustrisTNG hydrodynamic simulation. We speculate that the major driver of intra-cluster light growth, especially at large radii, is associated with cluster mass growth. Finally, we find that the colour of the cluster central galaxy and intra-cluster light displays a radial gradient that becomes bluer at a larger radius, which is consistent with a stellar stripping and disruption origin of intra-cluster light as suggested by simulation studies.
Emission line predictions for mock galaxy catalogues: a new differentiable and empirical mapping from DESI
Authors: Khederlarian Ashod , Newman Jeffrey A , Andrews Brett H , Dey Biprateep , Moustakas John , Hearin Andrew , Juneau Stéphanie , Tortorelli Luca , Gruen Daniel , Hahn ChangHoon , Canning Rebecca E A , Aguilar Jessica Nicole , Ahlen Steven , Brooks David , Claybaugh Todd , de la Macorra Axel , Doel Peter , Fanning Kevin , Ferraro Simone , Forero-Romero Jaime , Gaztañaga Enrique , Gontcho Satya Gontcho A , Kehoe Robert , Kisner Theodore , Kremin Anthony , Lambert Andrew , Landriau Martin , Manera Marc , Meisner Aaron , Miquel Ramon , Mueller Eva-Maria , Muñoz-Gutiérrez Andrea , Myers Adam , Nie Jundan , Poppett Claire , Prada Francisco , Rezaie Mehdi , Rossi Graziano , Sanchez Eusebio , Schubnell Michael , Silber Joseph Harry , Sprayberry David , Tarlé Gregory , Weaver Benjamin Alan , Zhou Zhimin , Zou Hu 
Published: May 2024

ABSTRACT
We present a simple, differentiable method for predicting emission line strengths from rest-frame optical continua using an empirically determined mapping. Extensive work has been done to develop mock galaxy catalogues that include robust predictions for galaxy photometry, but reliably predicting the strengths of emission lines has remained challenging. Our new mapping is a simple neural network implemented using the JAX Python automatic differentiation library. It is trained on Dark Energy Spectroscopic Instrument Early Release data to predict the equivalent widths (EWs) of the eight brightest optical emission lines (including H α, H β, [O ii], and [O iii]) from a galaxy’s rest-frame optical continuum. The predicted EW distributions are consistent with the observed ones when noise is accounted for, and we find Spearman’s rank correlation coefficient ρs &gt; 0.87 between predictions and observations for most lines. Using a non-linear dimensionality reduction technique, we show that this is true for galaxies across the full range of observed spectral energy distributions. In addition, we find that adding measurement uncertainties to the predicted line strengths is essential for reproducing the distribution of observed line-ratios in the BPT diagram. Our trained network can easily be incorporated into a differentiable stellar population synthesis pipeline without hindering differentiability or scalability with GPUs. A synthetic catalogue generated with such a pipeline can be used to characterize and account for biases in the spectroscopic training sets used for training and calibration of photo-z’s, improving the modelling of systematic incompleteness for the Rubin Observatory LSST and other surveys.
The impact of ozone on Earth-like exoplanet climate dynamics: the case of Proxima Centauri b
Authors: De Luca P , Braam M , Komacek T D , Hochman A 
Published: May 2024

ABSTRACT
The emergence of the JWST and the development of other advanced observatories (e.g. ELTs, LIFE, and HWO) marks a pivotal moment in the quest to characterize the atmospheres of Earth-like exoplanets. Motivated by these advancements, we conduct theoretical explorations of exoplanetary atmospheres, focusing on refining our understanding of planetary climate and habitability. Our study investigates the impact of ozone on the atmosphere of Proxima Centauri b in a synchronous orbit, utilizing coupled climate chemistry model simulations and dynamical systems theory. The latter quantifies compound dynamical metrics in phase space through the inverse of co-persistence (θ) and co-dimension (d), of which low values correspond to stable atmospheric states. Initially, we scrutinized the influence of ozone on temperature and wind speed. Including interactive ozone [i.e. coupled atmospheric (photo)chemistry] reduces the hemispheric difference in temperature from 68 °K to 64 °K, increases (∼+7 °K) atmospheric temperature at an altitude range of ∼20–50 km, and increases variability in the compound dynamics of temperature and wind speed. Moreover, with interactive ozone, wind speed during highly temporally stable states is weaker than for unstable ones, and ozone transport to the nightside gyres during unstable states is enhanced compared to stable ones (∼+800 DU). We conclude that including interactive ozone significantly influences Earth-like exoplanets' chemistry and climate dynamics. This study establishes a novel pathway for comprehending the influence of photochemical species on the climate dynamics of potentially habitable Earth-like exoplanets. We envisage an extension of this framework to other exoplanets.
Potential surface ice distribution on close-in terrestrial exoplanets around M dwarfs
Authors: Ouyang Yueyun , Ding Feng 
Published: May 2024

ABSTRACT
Previous studies suggested that surface ice could be distributed on close-in terrestrial exoplanets around M-dwarfs if heat redistribution on the planets is very inefficient. In general, orbital and atmospheric parameters play an important role in the climate on terrestrial planets, including the cold-trap region where the permanent surface water reservoir can potentially be distributed. Here, we develop a simple coupled land-atmosphere model to explore the potential surface ice distribution on close-in terrestrial planets with various orbital and atmospheric parameters, assuming that the planets are airless or have a thin N2 atmosphere. We find that the most significant factors in deciding the surface cold trap region are the spin-orbit ratio and obliquity. The incident stellar flux and the surface pressure play a limited role in the thin N2 simulations for incident flux smaller than Mercury’s and surface pressure lower than 104 Pa. Our result illustrates the possible distribution of surface ice on arid terrestrial planets and can help to understand the climate of these exoplanets.
CN stretches around 4.4 microns dominate the IR absorption spectra of cyano-polycyclic aromatic hydrocarbons
Authors: Esposito Vincent J , Fortenberry Ryan C , Boersma Christiaan , Maragkoudakis Alexandros , Allamandola Louis J 
Published: May 2024

ABSTRACT
Anharmonic quantum chemical computations reveal a strong, narrow (width = 0.075 $\mu$m) band in the 4.3–4.5 $\mu$m region of the absorption spectra of the cyano-substituted polycyclic aromatic hydrocarbons (CN-PAHs) cyanonaphthalene, cyanoanthracene, cyanophenanthrene, and cyanopyrene. This narrow window with intense IR lines implies that CN-PAHs of various shapes and sizes offer little variation in both wavelength and intensity in this region. Subsequently, this band can be used as a tracer for CN-PAHs. The distinct features making up the band are assigned to mixed vibrational states consisting of the CN stretch fundamental and various combination bands, including in-plane CH bends, CC skeletal bends, and CC skeletal breathing motions. The extraordinarily large intrinsic intensity of the fundamental CN stretch is redistributed to nearby states via anharmonic coupling, which is readily captured when using second order vibrational perturbation theory with resonance polyad matrices. This redistribution of intensity leads to a complex spectrum. The intense bands in this wavelength region may contribute to the baseline continuum and undulating macroscopic structure seen in recent JWST NIRSpec observations.