bluuebunny/crossref_metadata_2025_split huggingface dataset:
P01-267 - Health-related Quality of Life (hrqol): Comparison Between Men with Prostate Cancer and Women With Breast Cancer Undergoing External Radiotherapy
Authors: Zeppegno P. , Allera O. , Colombo M. , Dalò V. , Lombardi A. , Grasso R. , Beldì D. , Masini L. , Gambaro G. , Krengli M. , Torre E. 
Published: June 2010

ObjectivesProstate and breast cancer share many similarities: high lifetime prevalence, increasing frequency, role of environmental factors, long survival also in metastatic disease and possibility of screening. The aim of this work is to evaluate the characteristics related to the patients, disease and treatment which can affect HRQoL at the beginning and after radiotherapy.Methodssince June 2009, we have recruited patients, providing informed consent, before radiotherapy (T0). We assess demographic characteristic (age, qualification, work, marital status…); neoplastic staging and grading; radiation dose and other antineoplastic treatment (hormonal/chemio-therapy or surgery); concomitant medical disease and pharmacological therapy. We evaluate HRQoL by EORTC-QLQ-C30 and EORTC-QLQ-PR25 (prostate-specific) or EORTC-QLQ-BR23 (breast-specific). The protocol also includes HADS, Paykel Life Events Scale and EPQ-R. The work is ongoing and implies a follow-up at 6 and 12 months (T1/T2).ResultsThe majority of men have a localized disease with Gleason score between 6 and 8 and the median pretreatment PSA is 10.52 ng/mL; 70% will undergo adjuvant-RT; median age is 69.30 years. Women have a median age of 58.46 years, all underwent surgery and all have a localized disease and positive receptorial status. Global QoL is lightly higher in the man sample; both groups report a major deficit at Emotional Function and high levels of Fatigue. The personological characteristic more represented is “Extravertion”.ConclusionsThe results show an association between worse QoL, “Nevroticism” and high Anxiety levels only in the men sample at T0. At the moment, there is no significant relation in the women sample.
P01-282 - Psychiatric Disorders in HIV Infected Patients in a General Hospital in Singapore
Authors: Lee J. , Kee J. , Tan L. 
Published: June 2010

IntroductionThe psychiatric reactions relating to Human Immunodeficiency Virus (HIV) infection cover the whole range of mental illnesses and psychosocial problems. This poses a challenge to both physicians and psychiatrists and is of immense relevance due to the rising number of HIV patients in Singapore.ObjectivesTo retrospectively examine the psychiatric disorders and related factors associated with HIV infected patients in a general hospital in Singapore.AimsTo review and describe the psychiatric disorders and related factors associated with HIV patients under the care of Tan Tock Seng Hospital and Communicable Disease Centre in Singapore.MethodsA 2-years retrospective descriptive study was performed on all HIV patients who were referred to the Department of Psychological Medicine of Tan Tock Seng Hospital for psychiatric assessment and this includes both inpatient and outpatient referrals. The data for inpatient referrals was obtained through the interdepartmental referral registry and relevant case notes. The data for outpatient referrals was obtained through the attendance and relevant case notes of the HIV psychiatric clinic. The data was collated and analyzed.ResultsMood disorders were the most common psychiatric disorders diagnosed and antidepressants were the most commonly used psychotropic drugs. Most patients were followed up on an outpatient basis for continuation of treatment.ConclusionsMany HIV infected patients may have concomitant psychiatric disorders. Clinicians may need to actively identify patients at risk and initiate early psychiatric consult to ensure appropriate care for these treatable disorders.
P01-286 - Transgender Sexual Behaviors in a Health Care
Authors: Iglesias Hernández M.I. , Ruiz Peña M. , Guerrero Díaz M. , Macías Sánchez M. , Bergero Miguel T. , Parres Gutiérrez C. , Meléndez García C. , Cano Oncala G. , Asiain Vierge S. 
Published: June 2010

IntroductionSexuality is a crucial area of human life. A proper examination to assess and detect problems in this field, it seems imperative to intervene when transsexual patients. Therefore accurately known, the sexual practices of these patients, allows us to work directly on possible alterations in the functioning of sexual life during the therapeutic process.ObjetivesDescribe patterns of sexual behavior in patients diagnosed with transsexualismScopeGender and Identity Disorder Unit (GIDU)SubjectSelected by consecutive sampling, 200 transsexuals treated at GIDU Malaga, aged between 20 and 40 years and who agreed to participate in the study. Comprising 142 transgender male-to-woman (MtW) and 58 women-to-man (WtM).MethodsWas conducted through a heterocompleted questionnaire that included questions about sexuality, personality traits and demographic characteristics. These were filled in the consultation and were anonymous.Results11.6% of MtW transsexuals have never had sex. 26.8% of the MtW and 29% of WtM are more than 3 months without masturbating. 54.1% of the MtW avoid having sex due to the rejection of his genitals, lack of sexual desire and previous traumatic experience. Transgender respondents had secondary education, stable jobs and they were single.ConclusionsIt is vital that we explore the sex lives of transsexual patients. This information must be integrated in a systematic and rigorous evaluation process. According to the results presented, the hyposexuality would be the most significant feature that describes sexuality for this population.
P01-290 - Depression and Quality of Life of Patients with Epilepsy in Malaysia
Authors: Mohamed S. , Gill J.S. , Tan C.T. 
Published: June 2010

ObjectiveTo determine the prevalence of depression and quality of life in patients with epilepsy, and its associated risk factors.MethodsThis was a cross sectional study where 120 patients with epilepsy and 60 controls who were the patients’ sibling, were recruited. Socio-demographic data (age, sex, race, marital status, education level and employment status) and clinical variables (age at onset, duration and type of seizure, seizure recency, type of antiepileptic drug used, family history of epilepsy and depression) were recorded. Both patients and the control subjects were given the “Hospital Anxiety and Depression Scale” and “Mini International Neuropsychiatric Interview” to screen and diagnose for depression respectively. The Quality of Life Inventory of Epilepsy (QOLIE-31) was used to assess quality of life.ResultsThe prevalence of depression in patients with epilepsy was higher than in controls (9.2% as compared to 3.3%), though it was not statistically significant. There were also no significant differences between the depressed and non depressed patients in terms of socio-demographic and clinical variables. However, patients with younger onset of epilepsy were more likely to report depressive symptoms on HADS (p = 0.02). Patients with epilepsy who were depressed also had poorer quality life as compared to those without depression: p< 0.001.ConclusionPatients with epilepsy had higher rates of depression as compared to controls. Furthermore they had significantly poorer quality of life as compared to those without depression. Therefore, epileptic patients should be regularly screened for depression to prevent unnecessary suffering and poorer quality of life.
P01-292 - Treatment Seeking Behaviour Among Cases Reported for Psychiatric Consultation with Co-morbid Infertility
Authors: Afridi M.I. , Iman N. , Khan H. 
Published: June 2010

ObjectiveTo assess treatment-seeking behaviour in psychiatric patients with co-morbid infertility.METHODology: This hospital-based prospective study was conducted on out-patients, consulted at NMI (Neuro-spinal & medical Institute), Karachi.All consecutive and consenting cases were interviewed using a semi-structured proforma. Results were tabulated and analyzed through SPSS Version 11.0. Fisher Exact test/Chi-square test were used to compare variables.ResultsOne hundred five cases (62.85% Men and 37.14% Women) that fulfilled the criteria of infertility were evaluated. More than half (51.42%) of the cases had sought alternative type of treatment including treatment from Faith Healers (19.04%), Hakeems (Eastern/Indigenous Practitioners=18.09%) and Homoeopathics(14.28%). The rest of the cases had history of multiple consultations with Allopathic medical practitioners.ConclusionThe impact of Infertility is serious especially in the east making a person vulnerable to seek help from the various available source of treatment particularly traditional/ alternative mode.
P01-295 - Psychiatric Disorder as Clinical Presentation of Primary Sjögren's Syndrome
Authors: Pelizza L. , Welsch B. , Bonacini F. , Losi R. , Ferrari A. 
Published: June 2010

BackgroundSjögren's syndrome (SS) is a common medical condition which may produce psychiatric disturbances. Psychoactive medications treat psychiatric symptoms, but leave the underlying process unaffected.AimsTo emphasize that psychiatric disorders in primary SS constitute an indisputable clinical reality that each practitioner must be able to recognize and treat.MethodA systematic review on psychiatric manifestations of SS and two case-reports of mental disorder as clinical presentation of primary SS.DiscussionPsychiatric manifestations in primary SS are common and can occur not only during its course, but also at onset of the autoimmune syndrome. A better adapted prescription of corticosteroids and/or immunosuppressive agents (together with specific psychotropic traetments) can induce to a rapid relief of psychiatric dysfunction.ConclusionsPsychiatrists should keep in mind that primary SS is a potential cause of mental disorders when examining patients with multiple somatic complaints and psychiatric symptoms.
P01-316 - Ethnicity and its Influence on Psychiatric Treatment in a Newly Established Greek Inpatient Unit
Authors: Apostolopoulos A. , Mandrapilia A. , Papadopoulou A. , Konstantinidou D. , Rizos E. , Douzenis A. , Lykouras L. 
Published: June 2010

ObjectivesEthnicity may influence treatment decisions and treatment quality in mental disorders. There have been suggestions of institutional racism in mental health services.MethodsIn this study we aimed to compare treatment quality between two groups: Greeks and immigrants and prove whether in our clinic, ethnicity is a significantly restricting factor of treatment quality. This study was conducted with all in-patients of Second Psychiatric Clinic University of Athens at Attikon Hospital between April and December 2008.ResultsA total of 101 in-patients aged 16-56 years old, were studed. There were 73 Greeks and 18 immigrants. The diagnoses were schizofrenia:36(49,31%) for Greeks and 10(55,55%) for immigrants, and mood disorders:37(50,68%) for Greeks and 8(44,44%) for immigrants. We considered that treatment quality is composed of factors such as: days of hospitalization, number of psychiatric medicines used before-during and after hospitalization, doses of: conventional and atypical antipsychotics, SSRI'S, SNRI'S, and mood stabilizers used before-during and after hospitalization.ConclusionIn this study ethnicity was not significantly associated with rates of polypharmacy during and after admition. There was a reduction of medication prescribed after admission in both groups. Immigrants had longer inpatient stays than Greek patients. We saw similar rates of antipsychotics used in both groups, but Greeks were more likely to take mood stabilizers and SSRI'S-SNRI'S. There were also higher rates of atypical antipsychotics than antipsychotics used in both groups.
P01-327 - New Dimensionsin Assessing and Treating Traumatic Stress: a Meta-analysis of Historical and Recent Contributions to the Field
Authors: French L.-A. , Nikolic-Novakovic L. 
Published: June 2010

ObjectivesNew dimensions of traumatic stress have surfaced since the inclusion of the PTSD classification in The Diagnostic and Statistical Manual of Mental Disorders-Third Edition (DSM-III) with its main focus on Vietnam Veterans. New Dimensions of traumatic stress entered the clinical/cultural equation with new populations, both military and civilian, subjected to massive disasters (hurricanes, floods, terrorist's attacks…) as well as those exposed to the potential of violence. The nearly four-year siege of Sarajevo and the constant fear of improvised explosive devices and suicide bombers among troops in Iraq and Afghanistan add another dimenstion of traumatic stress that falls outside the usually accepted “combat exposure” measure for a PTSD diagnosis. Our objective was to evaluate the scientific and clinical literature to see what assessment and treatment modalities are being employed to address this broader definition of traumatic stress.MethodsWe conducted a comprehensive review of journal articles and books published in English and the Slavic languages, the vast majority published within the past decade.ResultsThe search comprised of over 300 hits, mostly journal articles.ConclusionsAssessment tools have been expanded to include co-morbid clinical and health diagnoses as well as pre-morbid factors. Related clinical diagnoses include major depression and panic attacks while health concerns run the range of immune deficiency disorders as those associated with traumatic brain injuries. Psychopharmacology inroads seem to focus on Serotonin agonists while cognitive-behavioral approaches dominate the psychotherapies. Targeted populations include coalition troops (male & female) and those involved in the Bosnian and Kosovo conflicts.
P01-338 - An Abridged DSM-IV Cultural Formulation of a Psychiatric Case
Authors: Caballero L. , Pelaez C. , Drozdowsky E. 
Published: June 2010

BackgroundThe DSM-IV Cultural Formulation (CF) is the most important method of cultural assessment, but has not been sufficiently developed.Based on a case, a proposal is being done here of an Abridged CF trying to:1Identify the main cultural factors.2Link this abridged CF to the general clinical formulation.3Show the effectiveness in arrive at a differential diagnosis and garner patients’ adherenceClinical vignette: A Moroccan 23 year-old woman was admitted in a Psychiatric Service and diagnosed of a manic episode and harmful consumption of drugs and at the discharge she quickly relapsed.The incorporation of an Abridged CF on her second admission was crucial in building a better therapeutic relationship. There were different explanatory models acting in the case:a)her family thought that she was “bewitched” or that the cause were “drugs”;b)the clinicians’ explanatory model was that of biological predisposition to mania, triggered by her drug intake and other vulnerability factors.This procedure made it possible to reformulate her psychiatric condition and to associate therapeutic goals to the aims of her and her family. It clearly promote a more favourable course and outcome.ConclusionsA valid abridged CF could foster its broader use in clinical psychiatry, whereas a mandatory full CF runs the risk of being underuse and it would impoverish psychiatric practice and limit the acceptation of psychiatry as a universal brand of medicine.
P01-339 - Assessment of Spirituality History Taking in Mental Health
Authors: Raffi A. , Hussein N. 
Published: June 2010

IntroductionSpirituality is recognized as a key facet of a person's sense of self and wellbeing. In the UK 73% of psychiatrists reported no religious affiliation compared to 38% of their patients. 92% of psychiatrists in Britain believed that religion & mental illness were connected & religious issues should be addressed in treatment.AimsAudit Spirituality Assessments conducted in new cases admitted to hospital and new cases seen in clinic over a 3 month period(July-September 2009) in adult/elderly services.MethodsDemographic data was collected from electronic patient records and casenotes/clinic assessment letters were reviewed for evidence of taking a spiritual history. Guidance for how to take a spiritual history was sought from Royal College of Psychiatry guidelines and recently published journal article (Advances in Psychiatric Treatment.May 2007;13:212-219). Evidence of a brief screening of spirituality, followed by a more detailed assessment were recorded.Results75 cases were reviewed of which 39 were male and 36 female. There was an even distribution of age within the sample over 7 decades from age 20 to age 90. Of the 75 cases, only 2 (2.7%) had a brief assessment of their spirituality whilst the larger majority (97.3%) had no assessment. No detailed assessment of spirituality history was conducted.ConclusionsThe results indicate that assessment of spirituality is very poorly conducted in this sample and there is need for development. Recommendations from the audit include facilitation of further training in religion and spirituality history taking and for such training to be encompassed within induction training of junior doctors.
P01-340 - Acculturation, Acculturative Stress and Psychosocial Well-being in the Hospitalized Immigrant Patient
Authors: Revollo H.-W. , Qureshi A. , Collazos F. , Ramos M.D.M. , Martinena P. , Casas M. 
Published: June 2010

ObjectivesThere is no direct relationship between migration and mental health, certain risk (e.g. acculturative stress) and protective factors of psychosocial well-being are inversely related with psychopathology. Acculturation strategies have been found to be related to psychopathology however this relationship has been minimaly examined with psychosocial well-being. The objectives of this study are to examine the relationship between acculturative stress, acculturation, and psychosocial well-being.MethodsThe sample consists of 150 immigrant inpatients hospitalized in tertiary care between 18 and 65 years of age. Acculturative stress, acculturation, social adaptation, anxiety and depression, as well as sociodemogrpahic and attitudinal items were evaluated.ResultsWith general health situation controlled, the study found a negative relationship between acculturative stress and psychosocial well-being, as well as between the marginalization acculturation strategy and psychosocial well-being. A relationship was found between acculturation strategies and acculturative stress. There is no positive relationship between the integration acculturation strategy and psychosocial well-being, although the majority of the study participants preferred integration, followed by assimilation. The latter is associated with lower levels of acculturative stress and higher psychosocial well-being. Separation, on the other hand, is associated with lower levels of anxiety and depression, and with a higher quality of life.ConclusionsNone of the acculturation strategies demonstrates a clear advantage in relation to psychosocial well-being, however, marginalization appears to be the least adaptive. It may be useful to revise the notion of what constitutes the most adaptive acculturation strategy for an individual, taking into account his or her psychosocial well-being.
P01-346 - A Case Report: the Dramatic Effects of Galantamine in a Patient with Early-onset Alzheimer's Disease
Authors: Agius M. , Dev H. , Zaman R. 
Published: June 2010

BackgroundA 51 year old former mid-wife presented with a 2 year history of increasing forgetfulness, with significant impairment to her daily function.She was diagnosed with non-familial early-onset Alzheimer's Disease (AD) and started on 8mg b.d. of Galantamine.MethodsWe gathered patient notes, consultant, collateral and personal accounts.Outpatient consultations were used to monitor Mrs LF's global, functional and behavioral progress. These were supplemented with the mini mental state examination (MMSE) which served as an objective test for her cognitive impairment, and a guide for her response to treatment.ResultsThe patient showed a marked improvement in MMSE from 23 (four months after the commencement of treatment in June 2004) to 29 (in September 2008). The MMSE has remained at 29 until the last consultation in September 2009. The patient accounts of social dysfunction due to her memory impairment pre-treatment highlights her gradual but significant recovery with Galantamine, to the point of being able to return to independent living arrangements and recently entering into a new relationship.Discussion and conclusionThe case raises interesting questions as to whether EOAD should be considered distinct to traditional AD, given the greater than expected response to Galantamine. The details of this single case, also lend themselves to supporting a reconsideration of the NICE guidelines for when treatment can be started, which would require further research. Such research may benefit from a long-term database in which data regarding MMSE scores of patients treated with Galantamine is serially recorded.
P01-353 - Use of Antipsychotic Medication in Older People with Dementia. An Inpatient Dementia Ward Audit
Authors: George M.K. , Pervez A. , Yahia A.O. 
Published: June 2010

Introduction80% of people with dementia experience one or more recurrent or persistent symptoms such as hallucinations, delusions, aggression, agitation, shouting, screaming, repetitive actions, sleep disturbance or wandering behaviour during the course of their illness (Ballard et al, 1995).These are collectively known as the behavioural and psychological symptoms of dementia.The clinical management may include both psychosocial and pharmacological measures such as the prescription of medication, including antipsychotics.Currently no drug is licensed for treatment of these symptoms in the UK and so clinicians need to be mindful of the fact that off label prescribing increases their professional liability in the event of an adverse event.Studies suggest that between 54% and 88% of antipsychotic use in residential homes may be inappropriate (McGrath & Jackson, 1996).Aims & objetivesTo identify the current antipsychotics prescribing practice for behavioural and psychological symptoms in dementia and its compliance with the NICE guidelines.MethodsA retrospective review of 50 case notes of the patients diagnosed with dementia after Nov 2006 was carried out.Results & conclusionsMajority of the patients were male and were in the age group of 70-80 years.Alzheimer's Dementia followed by mixed dementia & vascular dementia were the main diagnosis. The main antipsychotic prescribed was Quetiapine, closely followed by Haloperidol & Promazine.The study showed that the prescription of antipsychotics was appropriate and all patients have their target symptoms recorded. However documentation of risk benefits analysis and discussion with patient and family about risk's and side effects were lacking.