bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanisms of USP18 deISGylation revealed by comparative analysis with its human paralog USP41
Authors: Bonacci Thomas , Bolhuis Derek L , Brown Nicholas G , Emanuele Michael J 
Published: May 2024

ABSTRACTThe ubiquitin-like protein ISG15 (interferon-stimulatedgene15) regulates the host response to bacterial and viral infections through its conjugation to proteins (ISGylation) following interferon production. ISGylation is antagonized by the highly specific cysteine protease USP18, which is the major deISGylating enzyme. However, mechanisms underlying USP18’s extraordinary specificity towards ISG15 remains elusive. Here, we show that USP18 interacts with its paralog USP41, whose catalytic domain shares 97% identity with USP18. However, USP41 does not act as a deISGylase, which led us to perform a comparative analysis to decipher the basis for this difference, revealing molecular determinants of USP18’s specificity towards ISG15. We found that USP18 C-terminus, as well as a conserved Leucine at position 198, are essential for its enzymatic activity and likely act as functional surfaces based on AlphaFold predictions. Finally, we propose that USP41 antagonizes conjugation of the understudied ubiquitin-like protein FAT10 (HLA-Fadjacent transcript10) from substrates in a catalytic-independent manner. Altogether, our results offer new insights into USP18’s specificity towards ISG15, while identifying USP41 as a negative regulator of FAT10 conjugation.
Phoronids and their tubes harbor distinct microbiomes compared to surrounding sediment
Authors: Ettinger Cassandra L. , Eisen Jonathan A. 
Published: May 2024

AbstractPhoronids are a phylum of animals with only ∼12 described species, all of which are marine filter feeders that build external tubes for shelter and produce chemical deterrents against predators. Many tube-building invertebrates host distinct microbial communities and even have obligate symbionts for survival in sulfur-rich marine sediments. However, the microbiome of phoronids has yet to be comprehensively described. To address this, we surveyed the composition of the microbiome of the phoronid,Phoronopsis harmeri, using 16S rRNA gene amplicon and metagenomic sequencing. We found that the phoronid microbiome was dominated by members of the orders Campylobacterales, Desulfobulbales, and Desulfobacterales. We also found that the microbiomes of tubes and phoronids were less diverse than that of surrounding sediment, and that the microbiomes of phoronids, tubes and surrounding sediment were all distinctly structured. Based on analysis of metagenomic data, and even though we were only able to recover low quality MAGs of abundant taxa, we found preliminary evidence that taxa associated with phoronids and their tubes likely participate in sulfur cycling pathways. Future work should perform more robust metagenomic sequencing and chemical analysis to assess if there is a link between known phoronid chemical defenses and microorganisms. Overall, this study provides foundational insight into the microbial communities associated with phoronids and these initial findings suggest that these communities may play an important role in sulfur cycling in marine sediments.
Room-temperature serial synchrotron crystallography structure of Spinacia oleracea RuBisCO
Authors: Bjelčić Monika , Aurelius Oskar , Nan Jie , Neutze Richard , Ursby Thomas 
Published: May 2024

Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the enzyme responsible for the first step of carbon dioxide (CO2) fixation in plants, which proceeds via the carboxylation of ribulose 1,5-biphosphate. Because of the enormous importance of this reaction in agriculture and the environment, there is considerable interest in the mechanism of fixation of CO2 by RuBisCO. Here, a serial synchrotron crystallography structure of spinach RuBisCO is reported at 2.3 Å resolution. This structure is consistent with earlier single-crystal X-ray structures of this enzyme and the results are a good starting point for a further push towards time-resolved serial synchrotron crystallography in order to better understand the mechanism of the reaction.
Navigating organizational diversity: addressing transphobia among human resources professionals
Authors: Baptista José , Costa Dália , Gonçalves Sónia P. 
Published: May 2024

PurposeThis study aims to analyze the relationship between attitudes towards organizational diversity and towards trans people, correlating them with the levels of transphobia among HR professionals. Drawing upon the Intergroup Contact Theory, we also seek to understand whether the results may be influenced by the contact variable.Design/methodology/approachData were collected through the administration of a questionnaire to a sample of 184 HR professionals. The questionnaire was comprised of self-constructed questions and previously validated scales, including: Attitudes Toward Diversity Scale (ATDS) (Montei et al., 1996), Attitudes Toward Transgendered Individuals (ATTI) Scale (Walch et al., 2012) and Genderism and Transphobia Scale (GTS) (Hill and Willoughby, 2005).FindingsThe results do not show high levels of negative attitudes towards organizational diversity or intolerance towards trans people, being these variables correlated, with higher levels of intolerance in the portion of the sample without contact with trans people.Originality/valueThis article contributes to the increase of knowledge in the field of HR Development Policies focusing on the thematic of Diversity and Inclusion, which is a very current and important topic in organizations today. Also, the relevance and contribution of the study point to the need for Human Resources Management Practices that take on positive discrimination and/or encourage the adoption of affirmative actions by organizations.
Export manager profile in small and medium-sized enterprises: a gender issue?
Authors: Vidal-Suárez Marta M. , López-Duarte Cristina , González-Torre Pilar L. 
Published: May 2024

PurposeThe purpose is to explore the existence of different export manager profiles in terms of managerial attributes and personal traits according to gender. The study aims to answer two research questions: (1) Do export manager profiles differ depending on gender? If so, (2) which are the traits or managerial attributes that differ by gender and which is the relationship among them?Design/methodology/approachThe article relies on a quantitative empirical analysis of a sample of export managers of Spanish small and medium-sized enterprises (SMEs).FindingsOur results point to the existence of gendered export manager profiles that differ in terms of objective managerial attributes, personal traits, managerial styles and subjective perceptions relative to discriminatory practices and detrimental stereotypes. Two gender-specific substitution effects exist: one between managers’ experiential skills and their formal education and the other between managers' entrepreneurial orientation and the use of relational networks.Research limitations/implicationsOur data are limited in terms of geographical scope and firms size; therefore, our results are no generalizable without new studies on this issue.Practical implicationsOur findings can help firms to understand the relevance of export teams that encompass different gender managers and benefit from the combination of diverse managerial attributes, personal traits and relational processes in their international growth.Originality/valueGender is an scarcely studied issue in international business and management literature despite its relevance in the international institutional context. This article addresses the gender aspect of export management.
Practice challenge recommendations in online judge using implicit rating extraction and utility sequence patterns
Authors: P Natarajan Ramesh , S Kannimuthu , D Bhanu 
Published: May 2024

PurposeThe existing traditional recommendations based on content-based filtering (CBF), collaborative filtering (CF) and hybrid approaches are inadequate for recommending practice challenges in programming online judge (POJ). These systems only consider the preferences of the target users or similar users to recommend items. In the learning environment, recommender systems should consider the learning path, knowledge level and ability of the learner. Another major problem in POJ is the learners don't give ratings to practice challenges like e-commerce and video streaming portals. This purpose of the proposed approach is to overcome the abovementioned shortcomings.Design/methodology/approachTo achieve the context-aware practice challenge recommendation, the data preparation techniques including implicit rating extraction, data preprocessing to remove outliers, sequence-based learner clustering and utility sequence pattern mining approaches are used in the proposed approach. The approach ensures that the recommender system considers the knowledge level, learning path and learning goals of the learner to recommend practice challenges.FindingsExperiments on practice challenge recommendations conducted using real-world POJ dataset show that the proposed system outperforms other traditional approaches. The experiment also demonstrates that the proposed system is recommending challenges based on the learner's current context. The implicit rating extracted using the proposed approach works accurately in the recommender system.Originality/valueThe proposed system contains the following novel approaches to address the lack of rating and context-aware recommendations. The mathematical model was used to extract ratings from learner submissions. The statistical approach was used in data preprocessing. The sequence similarity-based learner clustering was used in transition matrix. Utilizing the rating as a utility in the USPAN algorithm provides useful insights into learner–challenge relationships.
Evidence of the conditions affecting knowledge hiding among librarians in academic libraries
Authors: Kaffashan Kakhki Mojtaba , Zutshi Ambika , Refoua Shabnam , Maleksadati Iman , Behzadi Hassan 
Published: May 2024

Purpose
This study aims to identify and theorize the conditions affecting the formation of librarians’ knowledge-hiding behaviour in academic libraries.

Design/methodology/approach
This study is a qualitative research based on the grounded theory approach. The data collection method involved in-depth, semi-structured interviews. The data was analysed using the MAXQDA software in three stages: open, axial and selective coding. The study included 22 faculty members and experienced librarians from academic libraries. The participants were selected using a combination of targeted and snowball sampling techniques.

Findings
The study yielded 96 open codes, 24 axial codes and 18 selective general codes related to the axial category of knowledge hiding (KH). The librarians’ KH axial coding paradigm pattern was developed in an academic library setting. The study also highlighted some general consequences of KH in academic libraries, such as lobbying and creating knowledge rents, deterioration of organizational relationships and interactions, reducing the competitive advantage of academic libraries and hindering individual and organizational learning.

Originality/value
This study has made a valuable contribution to the identification and explanation of the factors that affect KH. In addition, it has filled a research gap within the library and information science (LIS) field. The findings of the study may offer managers new strategies for addressing the occurrence of KH in academic libraries, and they also add to the existing literature on knowledge management in LIS.
Impact of information accessibility and diagnosticity on eye movements of children searching for information
Authors: Sun Jia-Rui , Wu Ko-Chiu 
Published: May 2024

Purpose
This study aims to explore the eye movement behavior of preadolescent children accessing and diagnosing information.

Design/methodology/approach
The researchers tracked the eye movements of 30 children with an eye-tracking apparatus. Using the kit of factor-referenced cognitive tests to measure perceptual speed and associative memory, they measured information-searching behavior with screen recordings, the data of which were analyzed by IBM SPSS Statistics 26.

Findings
Regarding information accessibility, there was a correlation between the child’s age, associative memory and the number of round-trip choices, and there were differences in the total fixation area among children of different age groups. Regarding diagnosticity, perceptual speed was positively correlated with the total fixation area, and the number of round-trip choices was negatively correlated with fixation duration.

Originality/value
Empirical evidence suggests that during information encoding, perceptual speed is the most important influencing factor. Extensive research indicates that children predominantly rely on recall and familiarity when searching for new information, both of which play roles in associative memory. Through an examination of the psychological and behavioral indicators of children, the study elucidated the cognitive processes involved in information processing and how children engage with information at both visual and cognitive levels.
Financial globalization, governance and economic growth in Sub-Saharan Africa
Authors: Adjei Audrey Afua Foriwaa , Gatsi John Gartchie , Owusu Appiah Michael , Abeka Mac Junior , Owusu Junior Peterson 
Published: May 2024

Purpose
The study aims to assess the interplay between financial globalization, effective governance and economic growth in sub-Saharan African (SSA) economies.

Design/methodology/approach
This study uses the Generalized Method of Moment Estimation and the Panel Quantile Regression techniques to analyze how financial globalization and governance impact sub-Saharan African economies.

Findings
The results show that governance is vital to the region's economic development. In order to achieve significant growth, sub-Saharan African economies must prioritize actions that promote good governance.

Research limitations/implications
The study is limited to sub-Saharan African economies.

Practical implications
It is crucial for the sub-Saharan Africa economies to concentrate on strengthening governance frameworks in order to realize its full economic potential because improvements in governance quality would have a favorable effect on economic growth.

Social implications
The findings indicate that both capital inflows and governance dynamics are essential for fostering economic growth in SSA economies. Also, balancing globalization's benefits with effective governance is crucial for promoting sustainable growth in SSA.

Originality/value
This paper fills a gap in literature by using the KOF financial globalization index to assess the impact of financial globalization and governance on economic growth in sub-Saharan African economies.
Advancements and forecasts of digital taxation information systems usage and its impact on tax compliance: does trust and awareness make difference?
Authors: Al-Okaily Manaf 
Published: May 2024

Purpose
The main purpose of the current study was to develop a new research model in the hope of providing a further understanding of Digital Taxation Information Systems (DTIS) usage and its impact on tax compliance by investigating the mediating role of trust in e-government services (TIE) and the moderating role of awareness (AW) toward these systems.

Design/methodology/approach
A quantitative research method approach with Partial Least Squares-Structural Equation Modelling (PLS-SEM) was employed to analyze the data collected.

Findings
The results indicated that DTIS usage is influenced by perceived usefulness (PU), perceived ease of use (PEU), attitude (ATT), knowledge (KN), subjective norm (SN), AW and TIE. Contrary to what is expected, AW does not moderate the association between SN and DTIS usage. Eventually, the results also revealed that TIE has mediated the association between trust in government (TIG) and DTIS usage.

Originality/value
This study provides thought-provoking empirical pieces of evidence about understanding the situation of DTIS usage and its impact on tax compliance among academic professors in Jordan. Furthermore, the study outcomes and discussion presented will help the Jordanian government improve and comprehensively formulate strategies to increase the tax compliance procedure.
Mixed-methods approach to investigating the diffusion of FinTech services: enriching the applicability of TOE and UTAUT models
Authors: Bouteraa Mohamed 
Published: May 2024

Purpose
The rapid global use of Financial Technology (FinTech), an innovative and advanced technology, is leading to the replacement of traditional financial services. Despite this, consumers in the United Arab Emirates are still not accepting FinTech services as anticipated. This study aims to investigate the barriers preventing consumers from using FinTech services in the banking industry based on the technology-organisation-environment (TOE) framework and anchored by the unified theory of acceptance and use of technology (UTAUT).

Design/methodology/approach
The current study used an exploratory sequential mixed-method design. A purposive sample was used to conduct preliminary semi-structured interviews with ten banking practitioners. These interviews aimed to explore the obstacles that hinder consumers from adopting FinTech services. To provide further empirical validation, the conceptual model has been systematically examined through a quantitative cross-sectional online survey encompassing a sample of 332 bank customers.

Findings
The qualitative investigation highlighted six new barriers to the usage of FinTech based on TOE’s model attributes. Through quantitative data analysis, the preliminary qualitative findings were primarily verified. It was discovered that self-efficacy, electronic word-of-mouth, system quality and bank image substantially influence consumers to use FinTech services, in addition to performance expectancy and facilitating conditions. Meanwhile, IT features and governmental support were found to have insignificant effects. Yet, government support was found to have a positive moderating role in strengthening social influence and system quality towards customer use of FinTech. Thus, the research supports the UTAUT and TOE models’ fitness for explaining FinTech usage with high predictive relevance.

Originality/value
This study is the authors’ pioneering effort to propose a comprehensive research framework that integrates the UTAUT and TOE models to tackle the limited adoption of FinTech services among consumers. Moreover, the study specifically examined the moderating influence of government support to propose an integrated model. Remarkably, this study is one of the initial attempts to investigate the adoption of FinTech using a mixed-methodology approach by incorporating quantitative and qualitative methods within a single inquiry to yield more comprehensive and insightful findings than research that relies on a single method.
Money laundering and terrorist financing risks and democratic governance: a global correlational analysis
Authors: Kalokoh Amidu 
Published: May 2024

Purpose
This paper aims to examine the association between money laundering (ML)/terrorist financing (TF) risks (hereafter, money laundering risks) and democratic governance across 117 countries.

Design/methodology/approach
A cross-sectional design was used to examine the association between ML risks and democratic governance by a quantitative approach. The findings are based on annual ratings of 117 countries on ML/TF risks and democracy while controlling for criminality and peace. The data was compiled from the Basel Anti-Money Laundering/Countering Financing Terrorism Risks Index, the Economic Intelligence Unit (Democracy Index), the Global Initiative against Transnational Organized Crimes (Criminality Index) and the Institute for Economics and Peace Index for 2020.

Findings
A multiple linear regression model found a statistically significant negative association between democratic governance and ML risks (B = −0.354, t = −7.454, p = <0.001) and a significant positive association between criminality and ML risks (B = 0.242, t = 2.692, p = 0.008).

Research limitations/implications
A cross-sectional design cannot determine causal inferences and generalization (Levin, 2006). The study only used a year to examine the hypothesis of a negative correlation between ML risks and democratic governance, thus making generalization difficult.

Originality/value
Extant literature examined ML, terrorism and AML diversely. There was a need to estimate the association between ML risks and democratic governance, especially globally, during a global crisis like COVID-19, when democratic principles, such as the rule of law, transparency and accountability, are challenged. Many personnel were laid off, thus limiting supervision for ML and TF. This study presents evidence of this association.
Mapping the International Valuation Standards ESG criteria and sustainability rating tools adopted at scale by the Australian commercial real estate market
Authors: Ghosn Cida , Warren-Myers Georgia , Candido Christhina 
Published: May 2024

PurposeThe proliferation of environmental rating tools over the past two decades has endeavoured to assist the industry in measuring sustainability. Recent changes to the International Valuation Standards (IVS) have directed valuers to consider ESG. The purpose of this study aims to examine how commonly utilized sustainability tools, which have been employed to communicate building sustainability credentials, align with the IVS categories of ESG.Design/methodology/approachThe research utilises the IVS categorisation of ESG and maps sustainability tools adopted at scale by the Australian Commercial Real Estate market. The approach identifies the various attributes within the commonly utilised rating tools that align with IVS defined ESG criteria.FindingsThe mapping provides insights into the coverage of the IVS ESG criteria in the mainstream tools used in Australia. Further, the research identifies existing sustainability criteria that are relevant to the built environment, that have not been clearly identified by the IVS, but have an important role in evaluating the sustainability of commercial real estate.Practical implicationsFor investors, occupiers and valuers, this research provides insights on how the current, commonly utilised sustainability rating tools align with the IVS-defined ESG metrics. This research assists in providing greater clarity regarding the relationship between ESG criteria and existing rating tools, which have been recently identified as key considerations in valuation practice and help to provide transparency and understanding for property stakeholders.Originality/valueThe importance of monitoring, reporting and enhancing transparency in ESG disclosures has emerged as a central issue with significant implications for the property industry. This research provides the first evaluation of how existing sustainability rating tools map against ESG criteria as directed in the IVS.