bluuebunny/crossref_metadata_2025_split huggingface dataset:
A big threat : Aflatoxin
Authors: Tiwari Ritu , Pandaya Aanal , Gulati Poornima , Chahuan Aishwarya 
Published: May 2024

The past decade has witnessed a tremendous surge of interest in herbal medicines throughout the world. Aflatoxins are naturally occurring mycotoxins that are mainly produced by Aspargillus flavus and Aspargillus parasiticus and primarily contaminate food crops such as corn, groundnuts, and tree nuts as well as herbal medicinal plants in tropical and subtropical regions of the world. It is a lethal substance that intensely or at slower ingestion influences the strength of humans and animals. Aflatoxin study is vital for a safety perspective as they are extremely lethal and cancer-causing; to overcome the health effect of aflatoxins and for better assessment and standardization of herbal plant drugs. The investigation includes worldwide regulations on aflatoxins with their acceptable ranges in commodities. With more controls for adequate dimensions of aflatoxins set up, present-day analytical techniques have turned out to be very modern, capable of accomplishing results with high accuracy and precision, appropriate for administrative research centers and post-reap sample testing in developed countries.
PRÁTICAS DE MATRICIAMENTO DESENVOLVIDAS PELOS CAPS NO CONTEXTO DA PANDEMIA DA COVID-19
Authors: Soares Pereira Halana , Miranda dos Santos Jarlan 
Published: May 2024

Introdução: O Centro de Atenção Psicossocial (CAPS) deve realizar práticas em saúde mental em uma perspectiva de cuidado territorial. Neste sentido, é esperando que as ações aconteçam em articulação com as equipes da Saúde da Família (SF) e do Núcleo Ampliado em Saúde da Família (NASF). Diante do atual contexto pandêmico e das mudanças e desafios que este momento trouxe, surge a necessidade de identificar e compreender como as práticas de matriciamento estão sendo realizadas pelas equipes do CAPS, no diálogo com os profissionais do NASF, SF, ou demais equipes da rede.
Objetivo: Identificar e analisar as práticas de matriciamento realizadas pelos CAPS com demais equipes da rede de saúde mental no decurso da pandemia do COVID-19.
Método: A produção dos dados dessa investigação foi realizada a partir da pesquisa documental. Com um recorte temporal entre março de 2020 e dezembro de 2021, buscamos identificar postagem no formato de foto e vídeo que divulgassem ações de saúde mental desenvolvidas pelos CAPS no período da pandemia da COVID-19, publicadas nas redes sociais (instagram e Facebook) dos serviços. Ao todo, foram identificados os perfis de 22 CAPS, situados em 18 cidades do estado da Bahia. Em relação ao eixo matriciamento, foram analisadas 01 vídeos e 14 fotos.
Resultados (esperados / parciais): Observa-se durante a análise, a partir dos registros encontrados nas redes sociais, que poucos foram os encontros de matriciamento realizados pelos CAPS durante a pandemia. Há uma lacuna temporal de seis meses em que nenhum CAPS realizou atividades de matriciamento, sejam elas na modalidade on-line ou presencial. Entre os CAPS analisados, identificamos apenas 06 CAPS que realizaram atividades de matriciamento: 02 (01 CAPS em Salvador e 01 CAPS em Serrinha) realizaram em ambas as modalidades. 02 realizaram apenas na categoria online (01 CAPS em Mairi e 01 CAPS em Salvador), e 02 procederam na forma presencial. (01 CAPS em Riachão do Jacuípe e 01 CAPS em Bom Jesus da Lapa). É notável a preferência dos profissionais por realizar as ações de matriciamento no primeiro semestre do ano. Ademais, podemos destacar a importância de que as práticas matriciais fossem regulares ao decorrer de todo o ano de atividades, visto que o apoio matricial é uma estratégia potente de gestão, ação terapêutica e pedagógica que pode contribuir para a otimização do sistema de saúde e qualificação do cuidado em saúde mental.
Descritores: Saúde Mental; Centro de Atenção Psicossocial; Pandemia da COVID-19; Matriciamento.
Eixo temático: Ciências da saúde.
O PAPEL DA FIBRA ALIMENTAR NO METABOLISMO HUMANO
Authors: Borges Silveira Ester , Samara Nogueira da Silva Milena , Sobral Neiva Gabrielly , Índira dos Anjos Ribeiro Iorrana 
Published: May 2024

Introdução: As Fibras alimentares são carboidratos de resistente digestão e absorção no intestino delgado, definidas como não digeríveis. Elas podem ser classificadas em solúveis e não solúveis. Ademais, os efeitos benefícios da fibra alimentar estão majoritariamente relacionados, pela comunidade científica e social, a melhoria do trânsito intestinal, por ser, em parte, fermentada no intestino grosso, além de favorecer o pH do cólon e a formação de subprodutos importantes para a fisiologia humana. No entanto, entender o papel da fibra alimentar sobre o metabolismo humano, visto que abrange todas as reações do organismo para a manutenção da vida, é essencial, podendo até contribuir para prevenção e tratamento de doenças metabólicas.
Objetivo: O objetivo deste projeto é compreender o papel desempenhado pela fibra alimentar consumida diariamente, em quantidade e qualidade ideal, no metabolismo humano.
Metodologia: Trata-se de uma revisão sistemática da literatura, a qual será realizada em quatro bancos de dados: SciELO, PubMed, BVS e LILACS. Exclui-se desta pesquisa os resumos, as dissertações e os relatos de casos ou os artigos publicados há mais de 15 anos. As estratégias de busca para as bases de dados foram definidas por termos relacionados a fibra dietética: Dietary fiber; Metabolic Processes; metabolic diseases; metabolic syndrome, Nutritional therapy. Seu desenvolvimento ocorre através de perguntas objetivas entre perspectivas positivas e negativas sobre o tema proposto a fim de comparar suas variantes, assim dando possibilidade de novas pesquisas relacionadas.
Resultados esperados: Sabendo que a fibra alimentar desenvolve um papel importante no organismo, espera-se encontrar fatores positivos que evidenciam a capacidade de mudanças e soluções para doenças metabólicas bem como a manutenção do trato intestinal. Através de pesquisas primárias, entende-se que dietas ricas em fibras alimentares são importantes para o controle do diabetes, melhora o controle glicêmico e lipídico, diminuição do peso corporal pelo aumento da saciedade, e do processo inflamatório, além da redução na mortalidade prematura. (REYNOLDS; AKERMAN; MANN, 2020). Dessa forma, utilizar a fibra dietética como parte da terapia nutricional no tratamento de doenças metabólicas, e principalmente na prevenção, é essencial para o avanço da nutrição clínica voltada para prevenção e tratamento de patologias. (CRONIN et al., 2021)
Descritores: Fibra dietética; Processos Metabólicos; doenças metabólicas; síndrome metabólica; Terapia nutricional.
Eixo temático: Ciências da Saúde- Nutrição.
ESTRATÉGIAS PSICOTERAPÊUTICAS DA TERAPIA COGNITIVA COMPORTAMENTAL NA SÍNDROME DE BURNOUT EM PROFESSORES DA EDUCAÇÃO FUNDAMENTAL
Authors: Paula Caldas Melo Ana , Maria Carvalho Soares de Sant´  anna Antonia , Cristina Braga Chaves Érica 
Published: May 2024

Introdução: Em face do cenário atual onde as coisas são tudo para ontem a Síndrome de Burnout (SB) tem afetado bastante a saúde do professor da Educação Fundamental, onde a Terapia Cognitiva Comportamental (TCC) vem contribuindo de maneira significativa para prevenir e intervir com o intuito de tornar cada vez mais produtiva a qualidade de vida desse trabalhador cujo estresse derivado do trabalho que ocupa tem manifestado no corpo os efeitos de uma vida laborativa extremamente desgastante o adoecendo física e psiquicamente com tanta fadiga e exaustão. Para Tavares (2001) essa síndrome despersonaliza o indivíduo, chegando a causar uma exaustão emocional profunda. No auge da vida moderna independente da visão apresentada por cada autor essa síndrome vem a causar no trabalhador uma ausência de si mesmo. A Síndrome de Burnout (SB) é uma síndrome psicológica que resulta do trabalho laboral extremamente desgastante adoecendo psiquicamente o indivíduo. E diante das imensas demandas enfrentadas pelos professores vem ser esta uma das classes de profissões mais acometidas por esta síndrome que vem viralizando atualmente no sistema educacional. Estudiosos afirmam ser o trabalho tão exaustivo que seu impacto negativo chega a causar ilusão pelo trabalho realizado, além de indolência e sentimento de culpa, podendo afetar diversos profissionais que mantém relação constante e direta com outras pessoas. Pesquisas ainda observaram que a jornada exaustiva enfrentada pelos professores em sala de aula estende-se ainda para fora do ambiente escolar. As condições de trabalho como a sobrecarga de tarefas e a falta de interesse dos estudantes torna-se fator constante de desmotivação.
Objetivo: Levantar estratégias psicoterapêuticas da Terapia Cognitiva Comportamental (TCC) no tratamento da Síndrome de Burnout (SB)
Método: Será utilizado o método sistemático de levantamento bibliográfico por meio de livros e buscas eletrônicas indexadas nas bases de dados do Google Acadêmico, Scielo ( Scientific Eletronic Library Online), BvSalud (Biblioteca Virtual em Saúde) e acervo da BDTD ( Biblioteca Digital Brasileira de Teses e Dissertações), dentro do recorte temporal de 2012 a 2022.
Resultados (esperados / parciais): Esta pesquisa busca aprofundar os estudos dos efeitos nocivos do trabalho em excesso mostrando revelar como tal prática pode afetar profundamente a qualidade de vida do trabalhador e como a Terapia Cognitivo Comportamental (TCC) pode tornar-se relevante no processo.
Descritores: Síndrome de Burnout; Terapia Cognitiva Comportamental; Professores da Educação Básica
Eixo temático: Ciências da saúde.
Assessment of effects of duration and dosage of Amlodipine on gingival health - A Prospective Study
Authors: Guttal Kruthika S. , Karkera Namratha , Arunkumar Shantala , Nandimath Kirty 
Published: May 2024

Objectives:
Calcium channel blockers are one of the most commonly used drugs for the management of cardiovascular disorders and are known for causing gingival overgrowth as an adverse effect. Disfiguring gingival overgrowth triggered by this medication is not only esthetically displeasing but also often impairs nutrition and access to oral hygiene, resulting in increased susceptibility to oral infection, caries, and periodontal diseases. The present study aimed to correlate the incidence of the extent of gingival enlargement in hypertensive patients receiving amlodipine and also a correlation of the extent of gingival enlargement with the dosage and duration of intake of Amlodipine.

Materials and Methods:
Hypertensive patients attending the outpatient of the Department of Oral Medicine and Radiology were selected for the study. A detailed history of the subjects was recorded for single or multiple drug usage, including the intake of amlodipine medications for hypertension, the dose and duration of the drug usage, following which a clinical examination was performed to evaluate the grades of gingival enlargement and local factors affecting the same.

Results:
The majority of the patients (81%) received 5 mg of amlodipine medication, and more than 40% of patients were receiving amlodipine for more than one year. More than 50% of patients had grade 2 gingival enlargement. There was a significant correlation between gingival enlargement and amlodipine dosage. Also noted was an association between gingival enlargement and duration of receiving amlodipine.

Conclusion:
Even with a minimal dose of amlodipine, significant gingival enlargement is seen; hence, regular follow-up with a suitable dental evaluation referral for examining gingival and periodontal status becomes imminent. Therefore, dental professionals need to identify and then guide the patient to seek the necessary medical intervention for the same.
Comparison of non-mesh vs mesh technique for inguinal hernias. A randomized clinical study.
Authors: Viqar Aslam  , Muhammad Bilal  , Waqar Alam Jan  , Alina Zaidi  , Muhammad Ayaz  , Lubna Gul  
Published: May 2024

Objective: To assess the efficacy of mesh with non-mesh techniques in the management of primary inguinal hernias. Study Design: Randomized Clinical Trail. Setting: Teaching Hospital Peshawar. Period: March 2022 till January 2023. Methods: This RCT study was conducted 166 on individuals with primary, reducible inguinal or inguino-scrotal hernias based on predetermined inclusion criteria. For the purpose of hernia repair, they were split into two groups: non-mesh and mesh repair. Computer-generated random numbers were contained in sealed opaque envelopes. Acute groin discomfort, the amount of time needed to return to duty, and sequelae were evaluated as clinical outcomes. SPSS version 23 was used to enter and analyzed the data. Results: Age range for mesh group was 33-65 while for non-mesh 34-65. Observed Male to female ratio was 9:1. In both groups, there was no discernible difference in pain. There were notable variations in the amount of time needed to resume work. Conclusion: Both repairs techniques are effective to treat hernias but mesh repair has superior results.
Pengembangan Media Kartu Kuartet untuk Keterampilan Menulis Kalimat Sederhana
Authors: Arfiana Rizma , Nanang  , Iqnatia  , Afakh  
Published: May 2024

This study aims to describe the quality of learning media produced in terms of validity and effectiveness as well as describe students' responses to quartet card learning media for simple sentence writing skills. The development of quartet card media uses the ADDIE model (Analyze, Design, Development, Implementation, and Evaluation). This research was conducted at UPT SD Negeri 23 Gresik. The subjects of this research were fourth grade students of UPT SD Negeri 23 Gresik. The techniques used for data collection are media validation and questionnaires. The data analysis techniques used were media and material expert validation analysis, student response questionnaire analysis, and media effectiveness analysis. As a result of the research, two media experts who are lecturers in the Elementary School Teacher Education study program and two material experts from classroom teachers IV UPT SD Negeri 23 Gresik declared the quartet card learning media for simple sentence writing skills to be "very valid" in terms of both validity and effectiveness. 85.71% and 82.85%, respectively, were the scores of the first and second media expert validators. In the meantime, 95% was the score obtained by the first material expert validator and 92.25% by the second. The medium was deemed effective when 90.7% of the students' completed assignments met the required standards. The quartet card learning media received an overall response rate of 87.79% from 43 students, indicating that the media was deemed "very positive".
Persepsi Pemuda Desa terhadap Pekerjaan di Sektor Pertanian (Studi Kasus di Desa Bajang, Kecamatan Pakong, Kabupaten Pamekasan)
Authors: Zuhriyah Amanatuz , Mabruhatin Aini 
Published: May 2024

Desa Bajang adalah desa yang sebagian besar masyarakatnya bekerja sebagai petani. Akan tetapi, petani di Desa Bajang didominasi petani yang sudah berumur tua dari pada petani muda. Hal tersebut mengakibatkan kurangnya kontribusi pemuda terhadap pertanian. Tujuan penelitian ini adalah (1) mengetahui persepsi pemuda Desa Bajang tentang pekerjaan pertanian (2) mengetahui faktor-faktor apa saja yang memiliki hubungan dengan persepsi pemuda Desa Bajang terkait pekerjaan di sektor ini digunakan 40 responden yang diambil dengan Accidental sampling. Pengumpulan data dilakukan melalui observasi, wawancara, dan penyebaran kuisoner. Data dianalisis menggunakan statistik deskriptif dan uji Chi-square. Hasil kajian menunjukkan bahwa sikap pemuda desa terhadap pekerjaan di bidang pertanian berada dalam kategori baik. Faktor -faktor yang yang berhubungan dengan persepsi pemuda terhadap pekerjaan disektor pertanian meliputi pekerjaan saat ini, pengalaman kerja dan pendapatan orang tua. Sedangkan faktor-faktor yang tidat ada kaitannya dengan persepsi pemuda desa terhadap pekerjaan disektor pertanian adalah jenis kelamin, usia, pendidikan terkhir dan sosiliasi.
Green Synthesis of 2-isonicotinoyl-4,6-dihydroimidazo[4,5-c] Pyrazol-5 (2H)-one Derivatives via One-pot Multicomponent Approach as a Potent Antifungal Agent
Authors: Mogle Prashant P. , Gaikwad Sunil V. , Pohare Santosh S. , Hebade Madhav J. , Gaikwad Milind V. , Dawane Bhaskar S. 
Published: May 2024

In the present research work, we made an effort to a green, efficient, and simple procedure for the one-pot multicomponent synthesis of novel 2-isonicotinoyl-4,6-dihydroimidazo[4,5-c] pyrazole-5 (2H)-one derivative in presence of environmentally sustainable PEG-400 reaction medium and recyclable catalyst bleaching earth clay (pH 12.5, 10% by weight). The benefits of this methodology include a quick reaction time, high product yield, and an easy work-up procedure. The antifungal potency was studied for synthesized derivatives using the agar well diffusion method against Aspergillus niger (MTCC280), Aspergillus flavus (MTCC3008), and Penicillium citrinum fungus strain. Among the tested compounds six from the nine compounds show promising antifungal activity among the tested compounds. The derivatives were characterized using 1H NMR, 13C NMR, Mass, and IR spectroscopic methods. Molecular docking study 2-isonicotinoyl-4,6-dihydroimidazo[4,5-c] pyrazole-5 (2H)-one derivative was conducted against the PDB : 3KHM, 14 α-demethylase (CYP51) from Trypanosoma cruzi in complex with inhibitor fluconazole protein and PDB : 6UW2 clotrimazole bound complex of Acanthamoeba castellanii CYP51.
تأثير انموذج بارمان بمصاحبة العرض المرئي في تعلم بعض المهارات الاساسية بكرة القدم للطلاب
Authors: Muhammad Hassan Hadi  , Prof. Dr. Rami Abdel Amir Hassoun  , Prof. Dr. Mazen Jalil Abdul Rasoul 3  
Published: May 2024

ان الاهتمام بطرائق التدريس ينبثق من الاهتمام بتطوير الطلاب عقليا، وجسميا وروحيا واجتماعيا واخلاقيا، واعدادهم وتأهلهم للدور المتوقع منهم بالمستقبل، وتطور المدرسين مهنيا واعدادهم للمسؤولية الملقاة على عاتقهم في اعداد الجيل ، ان اهمية نماذج التدريس الحديثة تكمن في اتجاهات عدة من اهمها جعل المتعلم هوا مصدر القرار ومحور العملية التعليمة وزيادة فعاليته واشراكه في جميع مراحل التعلم من خلال اكتشاف المشكلات وطرح بعض الحلول القابلة للنقاش وايضا عملية التقويم وهذا ما يزيد توسعت فهم الطالب وزيادة عملية التفكير وايضا الوصول الى المعلومات والاحتفاظ بها واستعمالها وقت الحاجة ، لذا ارتأى الباحثون استخدام انموذج بارمان في مجال تدريس مادة كره القدم بالوسائل المرئية في كلية التربية البدنية وعلوم الرياضة , والتي قد تساعد في تعلم الطلاب والوصول الى نتائج تعليمية مرغوبة وتطويرها من خلال اكتساب المعلومات اتجاه مادة كرة القدم التي تحتاج الى اعتماد طرائق واساليب تعليمية حديثة . ويهدف البحث الى التعرف على تأثير انموذج بارمان بمصاحبة العرض المرئي في تعلم بعض المهارات الأساسية بكرة القدم للطلاب
Preparation of novel Au-Nb3O7F nanosheets for the photodegradation of tetracycline hydrochloride
Authors: Wang Zhiyuan , Ren Li , Chen Zhi , Chen Yao , Tian Xin , Wei Guoying 
Published: May 2024

Water pollution caused by antibiotics is a growing problem and photodegradation by efficient catalysts is an environmentally friendly technology that can effectively degrade organic pollutants in water. Here, a novel method was innovatively used to synthesize niobium oxyfluoride (Nb3O7F) nanosheets decorated with Au nanoparticles, which is the first report for the composites of Au and Nb3O7F. We prepared the Nb3O7F nanosheets via hydrothermal synthesis followed by deposition of Au nanoparticles on their surface using HAuCl4. The prepared samples were characterized by XRD, HRTEM, XPS, and UV–Vis. The diameters of most Au NPs are ranging from 5 to 25 nm with an average size of about 16.9 nm, as well as the Nb3O7F nanosheets in size ranging from 200 nm to 700 nm. The chemical composition of the Au-Nb3O7F showed a Au/Nb atomic ratio of 1/10, as well as a Nb/O/F ratio of 3/7/1. UV–Vis spectrum reveals a largest absorption peak at 520 nm for the Au-Nb3O7F nanosheets. The prepared Au-Nb3O7F nanomaterials were applied to the visible-light photodegradation of tetracycline hydrochloride, with the photocatalytic degradation rate reached more than 50% under the optimal conditions within 1 h. Capture experiments indicated that h+ and •O2- are the main active substances involved during the course of the photodegradation. Furthermore, the proposed mechanism for the photodegradation of the novel Au-Nb3O7F nanosheets was given.
Osteoporosis and coronary heart disease: a bi-directional Mendelian randomization study
Authors: Zhang Junsheng , Xu Pai , Liu Rongcan , Gyu Jin Min , Cao Peng , Kang Chan 
Published: May 2024

BackgroundOsteoporosis (OP) and cardiovascular disease (CVD) are major global public health issues, especially exacerbated by the challenges of an aging population. As these problems intensify, the associated burden on global health is expected to increase significantly. Despite extensive epidemiological investigations into the potential association between OP and CVD, establishing a clear causal relationship remains elusive.MethodsInstrumental variables were selected from summary statistics of the IEU GWAS database. Five different components of BMD (heel BMD, LS BMD, FA BMD, FN BMD, and TB BMD) were used as OP phenotypes. CHD, MI, and stroke were selected to represent CVD. Multiple analysis methods were used to evaluate the causal relationship between CVD and OP comprehensively. In addition, sensitivity analyses(Cochran’s Q test, MR-Egger intercept test, and “leave one out” analysis) were performed to verify the reliability of the results.ResultsThe MR showed a significant causal relationship between CHD on heel BMD and TB BMD; in the reverse analysis, there was no evidence that OP has a significant causal effect on CVD. The reliability of the results was confirmed through sensitivity analysis.ConclusionThe study results revealed that CHD was causally associated with Heel BMD and TB BMD, while in the reverse MR analysis, the causal relationship between OP and CVD was not supported. This result posits CHD as a potential etiological factor for OP and prompts that routine bone density assessment at traditional sites (forearm, femoral neck, lumbar spine) using DAX may inadequately discern underlying osteoporosis issues in CHD patients. The recommendation is to synergistically incorporate heel ultrasound or DAX for total body bone density examinations, ensuring clinical diagnostics are both precise and reliable. Moreover, these findings provide valuable insights for public health, contributing to the development of pertinent prevention and treatment strategies.