bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compound Heterozygous Variants of CYP27B1 Causing Autosomal Recessive Vitamin D-Dependent Rickets Type 1A in an Indian Child
Authors: Kakkad Mitesh , Kakkad Khyati , Oza Chirantap 
Published: May 2024

Background:
Vitamin D-dependent rickets Type 1A (VDDR-1A) is a rare cause of rickets occurring due to variants of CYP27B1 responsible for encoding enzyme 1ά hydroxylase.

Clinical Description:
We report a 17-months-old girl who presented to us with clinical and radiological features of rickets. The biochemistry investigations suggestive of low calcium, low phosphorous, markedly elevated alkaline phosphatase and parathyroid hormone, high-normal 25 hydroxy Vitamin D level and inappropriately normal 1,25 dihydroxy Vitamin D levels, and no response to oral calcium and Vitamin D supplementation, prompted the diagnosis of VDDR-1A, which was proven genetically with a novel compound heterozygous variant.

Management and Outcome:
She was treated with oral calcitriol 1.5 μg/day and oral elemental calcium at 500 mg/day; after which at the 3-month follow-up, improvement in clinical, biochemical, and radiological features was observed.

Conclusion:
Following a clinical diagnosis of VDDR, genetic analysis is preferable to identify the variant and hence understand the genotype–phenotype correlation.
May–Thurner syndrome: The unexplored
Authors: Mathur Atul , Modi Ranjan 
Published: May 2024

Abstract
May–Thurner syndrome (MTS) is the pathologic compression of the left common iliac vein by the right common iliac artery, resulting in left lower extremity pain, swelling, and deep venous thrombosis. MTS is missed by many interventionists as there is no standard criteria to establish the diagnosis. Imaging plays an integral part in screening patients for MTS. Here, we present a series of cases of MTS, which may help clinicians to diagnose and treat MTS.
Activity of insecticide detoxification enzymes in Pectinophora gossypiella (Saunders): Implications for insect pest management in cotton crops
Authors: Koffi Kouakou Delphin , Kouakou Malanno , Kra Kouadio Dagobert , Bini Kouadio Kra Norbert , Ochou Ochou Germain 
Published: May 2024

The pink bollworm Pectinophora gossypiella is one of the most important endocarpic pests in cotton. In the management of this pest, the intensive use of synthetic insecticides has led to the reduction of its sensitivity to certain active ingredients. It is in this perspective that the study was conducted to determine the enzymes involved in the metabolism of insecticides in P. gossypiella. Insects were collected in five localities (Bouaké, Bouaflé, Vavoua, Sésuéla and Kounahiri) with high pest pressure in the southern cotton zone. The collected insects were ground for the determination of enzymes involved in insecticide metabolism. The analyses showed a significant increase in glutathione-δ-transferase activity in populations of Bouaké compared to the other localities. However, individuals from Séguéla expressed more esterase (alpha and beta) and oxidase activities. Alpha and beta esterase activities were also more expressed in Bouaflé individuals. The high enzymatic activity of esterases and oxidases in individuals from Séguéla and Bouaflé reflects a low sensitivity to insecticides in which esterases and oxidases are involved in the metabolism. On the other hand, in Bouaké, only glutathione- δtransferases are involved in the detoxification of insecticides.
Perception des impacts du changement climatique des agropasteurs et adoption des innovations au Niger
Authors: Siddo Seyni , Gambo Yahoussa , Hamadou Issa 
Published: May 2024

L’objectif de cet article est de déterminer l’importance des stratégies introduites auprès des agropasteurs dans le cadre de la résilience climatique en vue d’évaluer l’incidence de certains facteurs sur l’adoption des technologies. Pour atteindre cet objectif, une enquête est conduite auprès de 239 agropasteurs dans la zone périurbaine de Tahoua. Les données collectées ont été analysées avec la méthode Maximum Différence. Concernant les principaux paramètres climatiques et anthropiques affectant la production de biomasse des parcours, la majorité des producteurs a indiqué que c’était le retard et la fin précoce des pluies (42%), la mortalité prématurée des espèces annuelles (30%) et le ramassage de la paille (46%). Les stratégies d’adaptation les plus importantes étaient: ensemencement des aires des pâturages (1,00), culture fourragère à double usage (0,88) et banques d’intrants zootechniques (0,72). Les mesures les moins préférées sont résidus de ménage (0,32), blocs multi-nutritionnels (0,33) et traitement de la paille à l’urée (0,39). Les contraintes freinant l’adoption des stratégies etaient la disparition espèces végétales des sites ensemencées, la faiblesse du respect des règles des cadres de concertations villageoises et le déficit de l’approvisionnement en alimentsbétail. Ces résultats constituent des pistes pour l'évaluation des obstacles à l'adoption des stratégies afin d’accroitre l’efficacité de la vulgarisation des innovations en Afrique.

English title: Perception of climate change impacts of agropastoralists and adoption of innovations in Niger
The purpose of this paper is to determine the importance of strategies introduced to agropastoralists in the context of climate resilience in order to evaluate the impact of certain factors on the adoption of technologies. To achieve this objective, a survey is conducted among 239 agropastoralists in the peri-urban area of Tahoua. The data collected was analyzed with the Maximum Difference method. Concerning the main climatic and anthropogenic parameters affecting the production of rangeland biomass, the majority of producers indicated that it was the delay and early end of rains (42%), premature mortality of annual species (30%) and the straw collection (46%).The most important adaptation strategies were: seeding of pasture areas (1.00), dual-use fodder cultivation (0.88) and livestock input banks (0.72). The least preferred measures are household residues (0.32), multi-nutrient blocks (0.33) and treatment of straw with urea (0.39). The constraints hindering the adoption of strategies were the disappearance of plant species from sown sites, poor compliance with the rules of village consultation frameworks and a shortage of livestock feed supplies. These results provide avenues for assessing the obstacles to the adoption of strategies in order to increase the effectiveness of the popularization of innovations in Africa.
Evaluation of the antioxidant and anti-inflammatory properties of the hydroethanolic extract of the leaves of <i>Blighia sapida</i> KD Koenig
Authors: Dermane Affo , Tayama Warapissime , Kpoyizoun Pascaline Kindji , Kola Poyodi , Metowogo Kossi , Eklu-Gadegbeku Kwashie 
Published: May 2024

Blighia sapida is widely used in traditional medicine for the treatment of several diseases in Togo. This study aimed to assess the antioxidant and anti-inflammatory properties of Blighia sapida. To this end, a phytochemical screening was carried out, followed by an assessment of DPPH, total antioxidant capacity, ex vivo lipoperoxidation tests on Sprague Dawley rats, and an evaluation of anti- inflammatory activity by the egg albumin denaturation test. The leaves extract scavenged the DPPH free radical with an IC50 of 172 ± 0.577µg/mL and its total antioxidant capacity value was 40.174 ± 0.638 mg Eq AA/g. In the ex vivo lipoperoxidation test on the kidney and liver, the extract showed a significant inhibitory effect. Phytochemical tests revealed the presence of tannins, flavonoids, alkaloids, saponosides, and carbohydrate compounds. The present results showed that Blighia sapida leaves possess antioxidant and anti- inflammatory properties which may be linked to the bioactive compounds they contain, suggesting their use to prevent oxidative and inflammatory processes.
Contribution des parasitoïdes dans la lutte contre <i>Spodoptera frugiperda</i> (J. E. Smith) (Lepidoptera: Noctuidae) en Afrique de l’Ouest: cas de <i>Chelonus bifoveolatus</i> et <i>Coccygidium luteum</i> (synthèse bibliographique)
Authors: Ganou Simsin Fatoumata , Sankara Fernand , Agboyi Lakpo Koku , Dao Aichatou Nadia Christelle , Dabire Remy , Nebie Karim , Zida Issaka , Wangrawa Dimitri , Somda Irenee 
Published: May 2024

Depuis l’invasion de la chenille légionnaire d'automne, l'utilisation de pesticides chimiques semble être la seule méthode de lutte contre ce ravageur, mais cette pratique peut être nocive pour l'environnement et surtout pour les insectes utiles, et peut entraîner une résistance de la chenille. En Afrique, des études ont identifié plusieurs parasitoïdes indigènes capables de parasiter la chenille légionnaire et susceptibles d’être utilisés dans la lutte biologique contre ce ravageur. Cette revue de littérature avait pour objectif d’établir les différents parasitoïdes de la chenille légionnaire d’automne en Afrique de l’ouest ainsi que la biologie de Chelonus bifoveolatus et de Coccygidium luteum, deux parasitoïdes montrant un potentiel dans la lutte biologique contre la chenille légionnaire d'automne. L’utilisation de Chelonus bifoveolatus et Coccygidium luteum dans la lutte biologique a présenté des résultats intéressants, car ils ont permis de réduire la population de la chenille légionnaire d’automne en l’empêchant d’atteindre les stades larvaires voraces et en réduisant leurs dégâts. Davantage de recherches sont nécessaires pour maitriser la biologie de ces parasitoïdes et développer des méthodes efficientes de production de masse pour les lâchers en milieu réel.

English title: Contribution of parasitoids to the control of Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) in West Africa: the case of Chelonus bifoveolatus and Coccygidium luteum (bibliographic synthesis)
Since the invasion of the fall armyworm, the use of chemical pesticides seems to be the only method of controlling this pest, but this practice can be harmful to the environment and especially to beneficial insects, and can lead to resistance on the part of the caterpillar. In Africa, studies have identified several indigenous parasitoids capable of parasitizing fall armyworms, which could be used for biological control of this pest. This literature review aimed to establish the different parasitoids of the fall armyworm in West Africa, as well as the biology of Chelonus bifoveolatus and Coccygidium luteum, two parasitoids showing potential in the biological control of this pest. The use of Chelonus bifoveolatus and Coccygidium luteum in biological control has presented interesting results, since they have allowed to reduce the fall armyworm population by preventing it from reaching the voracious larval stages and reducing their damage. More research is needed to master the biology of these parasitoids and develop efficient mass production methods for real-world releases.
Caractérisation physicochimique et microbiologique des eaux de puits à usage de boisson de la ville d’Aboisso (Sud-Est de la Côte d’Ivoire)
Authors: Seki Thierry Oscar , Yapo Wolfgang Toussaint , Kpaibe Sawa Andre Philippe , Meless Djedjro Franck Renaud , Amin N'cho Christophe 
Published: May 2024

L’eau de boisson doit être potable. Cependant, dans la ville d’Aboisso, la qualité des eaux souterraines, captées par des puits creusés et utilisées comme alternative usuelle à l’eau du réseau public par plusieurs ménages, est mal connue. Ainsi, cette étude visait à évaluer les caractéristiques physicochimiques et microbiologiques d’eaux de puits à usage de boisson. Pour ce faire, 89 puits ont fait l’objet d’une inspection sanitaire suivie d’un contrôle de la qualité physicochimique et microbiologique de leurs eaux. Dans l'ensemble, les eaux analysées étaient acides (94,38%), moyennement minéralisées (61,80%) et douces (62,92%). La contamination physicochimique était soulignée par une turbidité et un taux de fer élevés, respectivement dans 67,42% et 51,69% des échantillons d'eau. Une proportion de 68,54% des puits présentaient une source de pollution dans un rayon de 15 m et 86,52% d'échantillons d'eau étaient contaminés microbiologiquement. Par ailleurs, une analyse en composantes principales et une classification ascendante hiérarchique ont réparti les puits en trois groupes dont le dominant (74,16%) était constitué par des puits ayant de faibles valeurs des différents paramètres analysés. Les ménages, avant de consommer ces eaux souterraines contaminées et continuellement exposées à la pollution, doivent convenablement les traiter.

English title: Physicochemical and microbiological characterization of well water for drinking purposes in the town of Aboisso (South- East of Ivory Coast)
Drinking water must be safe. However, in the town of Aboisso, the quality of groundwater, captured by dug wells and used as a usual alternative to public network water by several households, is poorly known. Thus, this study aimed to evaluate the physicochemical and microbiological characteristics of well water for drinking purposes. To do this, 89 wells were subject to a sanitary inspection followed by a control of the physicochemical and microbiological quality of their waters. Overall, the waters analyzed were acidic (94.38%), moderately mineralized (61.80%) and soft (62.92%). High turbidity and iron levels, respectively in 67.42% and 51.69% of the water samples, highlighted physicochemical contamination. A proportion of 68.54% of wells presented a source of pollution within a radius of 15 m and 86.52% of water samples were microbiologically contaminated. Furthermore, a principal component analysis and an ascending hierarchical classification divided the wells into three groups, the dominant of which (74.16%) was made up of wells with low values of the different parameters analyzed. Households, before consuming this contaminated groundwater continually exposed to pollution, must properly treat it.
Dynamique de la forêt à la lisière forêt-formation herbacée : Caractéristiques des espèces recensées à Bombo Lumene (Kinshasa-RD Congo) I.
Authors: Makumbelo E. , Lukoki L. , Belesi K. , Lungiambudila M. 
Published: May 2024

La dynamique du paysage est aujourd’hui suivie par ici par là à travers la planète. C’est dans cet optique qu’une analyse de la végétation de Bombo Lumene a été menée. Les résultats, à l’issue des inventaires floristiques dans un échantillon objectif délimité à la lisière forêt- formation herbacée, ont révélé une densité, une diversité floristique et biologique bien élevée. L‘analyse et l’interprétation approfondie de ces résultats par le Modèle LIFOSA-17C ont attesté qu’il y a une tendance dynamique en faveur de la forêt au niveau du système écologique et des habitats herbacés. Une gestion rationnelle des ressources naturelles renforcera cette dynamique.

English title: Dynamic of forest in forest-herbaceous formation edge: characteristics of species listed at Bombo Lumene (Kinshasa-DR Congo) I.
Dynamic landscape is today well attended here and there through planet. It’s in this objective that analysis of Bombo Lumene vegetation was carried out. Results at the conclusion of floristic inventory in objective sample delimited to edge forest-herbaceous formation reveled density, floristic and biological diversity well-mannered. Analysis and interpretation improve of this results by Model LIFOSA-17 testify that there is dynamic tendency in favor of forest up to standard ecosystems and settlements herbaceous.
Tantangan dan Peluang Kebijakan Moneter bagi Negara Berkembang di Era Globalisasi
Authors: Sodik Fajar Japar , Rachmansyah Fachridwan , Ananda Daffa Dwi , Wicaksono Dean , Fadilla Arif 
Published: May 2024

Fenomena globalisasi ekonomi dan ketidakpastian ekonomi telah memberikan tantangan baru bagi perumusan dan implementasi kebijakan moneter, yang menjadi pilar utama dalam menjaga stabilitas ekonomi suatu negara. Penelitian ini bertujuan untuk menyelidiki bagaimana kebijakan moneter, terutama dalam bentuk BI Rate di Indonesia, mempengaruhi pertumbuhan ekonomi dan tingkat harga. Metode penelitian yang digunakan adalah pendekatan kualitatif deskriptif, dengan mengumpulkan data dari literatur akademik dan dokumen kebijakan. Hasil penelitian menunjukkan bahwa kebijakan moneter memiliki dampak signifikan terhadap pertumbuhan ekonomi, inflasi, dan nilai tukar. Kesimpulannya, evaluasi kebijakan moneter di era globalisasi memberikan tantangan dan peluang bagi negara berkembang, dan peningkatan efektivitas kebijakan moneter dapat membantu dalam menghadapi tekanan globalisasi dan meningkatkan stabilitas ekonomi.
RELATO DE EXPERIENCIA DE TRADUCCIÓN DE UN MANUAL DE USO DE UN CÓDIGO FUENTE EN LA COMUNIDAD INVIDENTE
Authors: Oliveira Eliab Magalhães , Barbosa Aryella Karen Lima , Aguiar Pereira Laís de Sousa Nóbrega , Sousa Déborah Letícia Ferreira de 
Published: May 2024

ABSTRACT: The research originates from translating a usage manual for an audiogame within the visually impaired community during the pandemic. It aims to reflect on the experience of a novice visually impaired translator in translating the audiogame's technical content. Specific objectives include understanding visually impaired individuals' reality and the need for inclusion, explaining translation procedures, and describing novice translator and Spanish teacher difficulties. The study draws from Barbosa (2020) for technical procedures, Campos (1986) for translation basics, and Nóbrega (2020) and Aguiar Pereira (2022) for reflective insights. Findings reveal translation's potential to unveil hidden aspects of the visually impaired community, necessitating specific translator skills. Understanding this audience aids Spanish teachers in addressing their social context and needs, fostering inclusivity.

Keywords: Accessibility and Inclusion Process; Translation; Visual Impairment; Audiogames.
Examining the Impact of Six Pro-Vaccination Messages on MMR Vaccine Hesitancy Among Mothers in Ukraine
Authors: Atif (Nurzhynska) Anastasiya , Chappell Paul , Sukhodolska Anna , Sanders Jet G. 
Published: May 2024

The Ukrainian government began delivering mandatory MMR vaccination letters to parents across the country in 2019. In this two-phase online RCT, we aimed to test the effectiveness of this national mandatory vaccination letter against five behavioural science-informed letters, in terms of their effects on the vaccination attitudes, intentions and behaviours of Ukrainian mothers (N = 738). One letter was focused on the simplicity and accessibility of vaccination procedures; one contained a testimonial from a family doctor; two letters contained pro-vaccination social norm statements (one signed by a family doctor and one by a school director); and one contained a loss-framed message underlining the risks of non-vaccination. The results showed no difference between the conditions in terms of change in vaccination attitudes and intentions but there was an effect on behaviour (measured through clicking a link to schedule a vaccination). The letters signed by a family doctor, outlining how vaccination is a social norm, were most effective in encouraging positive vaccination behaviours. We conclude that the national template used by Ukrainian public health authorities is unlikely to reduce vaccine hesitancy or increase vaccination rates, and that letters emphasising the normative nature of vaccination could increase uptake in the Ukrainian context.
Estuary: A Natural Filter Emphasis on A Mathematical Model of Pollution in Mandovi River
Authors: Dr. Mangirish Varadkar  
Published: May 2024

An estuary is a partially enclosed coastal body of brackish water with one or more rivers or streams flowing into it and with a free connection to the open sea. These freshwater estuaries also provide many of the ecosystem services and functions that brackish estuaries do, such as serving as natural filters for runoff and providing nursery grounds for many species of birds, fish, and other animals. Estuaries are among the most productive ecosystems in the world. Mandovi River in Goa is one such important Estuary. A mathematical model is presented to protect the Ecosystem
Sergančiųjų cukriniu diabetu savikontrolės veiksmų analizė
Authors: Kristina Bevainytė  , Aldona Mikaliūkštienė  , Jurga Šuminienė  
Published: May 2024

Nuolatinė savikontrolė yra svarbiausia sėkmingo abiejų tipų cukrinio diabeto (CD) valdymo dalis. Nepaisant to, kad yra veiksmingų gydymo metodų ir sukaupta daug įrodymų, atskleidžiančių sveikos mitybos, fizinio aktyvumo, griežtos glikemijos kontrolės ir vaistų vartojimo naudą, daugelis žmonių susiduria su diabeto savikontrolės sunkumais ir nesugeba pasiekti tinkamo rizikos veiksnių kontrolės lygio, kuris gerokai sumažintų sunkių komplikacijų ir ankstyvo mirtingumo riziką. Siekiant užtikrinti gerą CD sergančių pacientų ligos kontrolę tikslinga tirti jų gydymo režimo laikymosi įpročius bei šių įpročių laikymosi kliūtis.
Tyrimo tikslas – išanalizuoti mokslinę literatūrą apie sergančiųjų CD savikontrolės veiksmus.
Tyrimo metodai. Atlikta sisteminė mokslinės literatūros apžvalga. Atrinkti straipsniai, kuriuose nagrinėjamas pacientų, sergančių CD, mitybos, fizinio aktyvumo, vaistų vartojimo rekomendacijų laikymasis bei glikemijos kontrolė. Mokslinės literatūros paieška atlikta duomenų bazėse PubMed, Web of Science, Science Direct, Up To Date naudojant reikšminius žodžius ir jų derinius: mitybos rekomendacijų laikymasis sergant cukriniu diabetu (angl. adherence to diet among patients with diabetes), sergančiųjų CD fizinis aktyvumas (angl. physical activity in patients with diabetes), sergančiųjų CD vaistų vartojimo režimo laikymasis (angl. medication adherence among patients with diabetes), sergančiųjų CD glikemijos kontrolė (angl. glycemic control among patients with diabetes). Iš viso atrinktos ir išanalizuotos 24 publikacijos nagrinėjama tema.
Rezultatai. Tyrimo rezultatai parodė, kad pacientų, sergančių CD, ligos kontrolė yra nepakankama visose tirtose srityse. Pastebėta, kad pacientai prastai laikėsi jiems pateiktų mitybos rekomendacijų. Pagrindinės to priežastys yra šios: žinių, švietimo apie mitybą sergant CD trūkumas, negalėjimas sau leisti įsigyti rekomenduojamų maisto produktų. Tik trečdalis pacientų laikėsi fizinio aktyvumo rekomendacijų. Neigiamą įtaką fizinio aktyvumo rekomendacijų laikymuisi turi rūkymas, moteriška lytis, aukštas glikozilintas hemoglobinas bei antsvoris. Didelė dalis pacientų nesilaikė vaistų vartojimo režimo. Moterys ir pacientai, mažai bendraujantys su sveikatos priežiūros specialistais, prasčiau laikėsi vaistų vartojimo režimo. Analizuojant mokslo publikacijas išsiaiškinta, kad pacientų glikemijos kontrolė nėra pakankama, tai dažniausiai susiję su antsvoriu, aukštu HbA1c bei moteriška lytimi.
Išvada. Prasta diabeto savikontrolė – reikšmingas veiksnys, darantis įtaką pacientų sveikatos būklei ir gyvenimo kokybei.
The impact of digital transformation on business-processes and economic development
Authors: Боташева Л.С. , Абазалиева Ф.Э. 
Published: May 2024

В статье рассматривается влияние цифровой трансформации на бизнес-процессы и экономическое развитие, а также анализируются ключевые аспекты этого явления. Рассматривается роль новых технологий, таких как искусственный интеллект, Big Data и блокчейн, в контексте цифровой экономики. Анализируются государственная политика и стратегии, направленные на развитие цифровых технологий, а также вызовы и перспективы этого процесса.
Digital transformation has become an indispensable factor in modern economic development, which has a significant impact on business processes and the economy as a whole. This article examines the impact of digital transformation on business processes and economic development, as well as analyzes key aspects of this phenomenon. The paper also examines the role of new technologies such as artificial intelligence, Big Data and blockchain in the context of the digital economy. The article analyzes government policies and strategies aimed at the development of digital technologies, as well as the challenges and prospects of this process.