bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prior Payment Status and the Likelihood to Pay Dividends: International Evidence
Authors: Twu Mia 
Published: July 2010

AbstractBy using the signaling model and the life‐cycle theory, I examine the importance of prior payment status in determining the likelihood to pay dividends. I categorize firms into those that paid dividends previously and those that did not. My results show that strong dividend stickiness exists and the determinants to pay differ significantly for the two groups of firms. High growth and low insider holdings make prior payers more likely to pay but prior nonpayers less likely to pay. Furthermore, prior payers are more sensitive to profitability and earned/contributed equity mix, while prior nonpayers are more sensitive to risk and dividend premiums. Finally, taking the prior payment status into account eliminates the problem of overestimating the portion of payers put forth by previous studies.
The Difference of Heart Rate Recovery between Males with and without Erectile Dysfunction
Authors: Dogru M. Tolga , Basar M. Murad , Haciislamoglu Ahmet 
Published: July 2010

Aim: In this study, we aimed to investigate the relationship between heart rate recovery (HRR) time and Chronotropic Index (CHIND) parameters, which also reflect autonomic function, after exercise stress test (EST) in males with or without erectile dysfunction (ED), and we investigated the relationship between HRR and CHIND and serum steroid hormone levels. Material and Methods: A total of 135 participants (mean age: 45.0 ± 11.8 years) were enrolled into the study. Detailed biochemical and hormonal analyses, 12‐lead electrocardiography and EST (Treadmill) were performed in all participants. Erectile function was assessed using the International Index of Erectile Function (IIEF) questionnaire form. Patients were categorized into two groups according to their IIEF scores as ED (+) (IIEF < 26) and ED (−) (IIEF ≥ 26). Afterward, statistical analyses were performed to evaluate the correlations between ED and HRR and CHIND. Results: A total of 65 patients were ED (+) (mean age 44.9 ± 6.4 years), while 70 patients (mean age 43.7 ± 7.7 years) had normal erectile status. There were statistically significant differences in CHIND (P = 0.015) and HRR time (P = 0.037) between ED (+) and ED (−) patients. In correlation analysis, IIEF score was found positively correlated with HRR and metabolic equivalent (MET) values (rHRR= 0.293, P = 0.037; rMETs= 0.388, P = 0.011, respectively). Linear regression analysis revealed that METs value and total exercise time had a more linear relationship with IIEF score compared to the other EST parameters (pMETs= 0.002 and pTET= 0.015, respectively). Conclusion: Chronotropic incompetence and dynamic postexercise autonomic dysfunction are present in ED patients. This condition may reflect decreased functional capacity and exercise intolerance in these patients. Ann Noninvasive Electrocardiol 2010;15(3):223–229
Consideration of the Impact of Reperfusion Therapy on the Quantitative Relationship between the Selvester QRS Score and Infarct Size by Cardiac MRI
Authors: Knippenberg Stephanie A. M. , Wagner Galen S. , Ubachs Joey F. A. , Gorgels Anton , Hedström Erik , Arheden Håkan , Engblom Henrik 
Published: July 2010

Background: It has previously been shown that there is a good agreement between the Selvester QRS score and myocardial infarct (MI) size determined by postmortem histopathology in patients with nonreperfused MI. Currently, however, most patients with acute coronary thrombosis receive reperfusion therapy. Therefore, the aim of this study was to test the hypothesis that early reperfusion alters the quantitative relationship between Selvester QRS score and MI size. Methods: Twenty‐seven patients with acute first‐time reperfused MI were studied. Infarct size was determined by delayed contrast‐enhanced magnetic resonance imaging (DE‐MRI) and estimated with the 50‐criteria/31‐point Selvester QRS scoring system 1 week after admission. The findings in the present study were compared with previous postmortem studies exploring the quantitative relationship between Selvester QRS score and MI size in nonreperfused patients. Results: The quantitative relationship between QRS score and MI size by DE‐MRI in the present study of early reperfused MI was significantly different from previous postmortem histopathology studies of nonreperfused MI (P < 0.0001). In the present study, each QRS point represented approximately 2% of the left ventricle, compared to approximately 3% in previous postmortem histopathology studies of nonreperfused MI. When only considering small to moderate MI sizes, there was no significant difference in the quantitative relationship between QRS score and infarct size (P > 0.05). Conclusions: There is a different quantitative relationship between QRS score and MI size in early reperfused MI compared to nonreperfused MI, partly explained by differences in MI size. Thus, the Selvester QRS scoring system may not be linearly related to MI size. Ann Noninvasive Electrocardiol 2010;15(3):238–244
Effect of Obesity on P‐Wave Parameters in a Chinese Population
Authors: Liu Tong , Fu Zili , Korantzopoulos Panagiotis , Zhang Xiaowei , Wang Shaohua , Li Guangping 
Published: July 2010

Objective: To study the association between obesity and P‐wave duration and dispersion (Pd) in order to evaluate the potential risk for atrial fibrillation development in Chinese subjects using the definitions applied for Asian populations. Methods: The study population consisted of 40 obese (body mass index (BMI) ≥ 25 Kg/m2, according to the World Health Organization classification for the Asian population) subjects and 20 age‐ and sex‐matched normal weight controls. Maximum P‐wave duration (Pmax), minimum P‐wave duration (Pmin), and Pd were carefully measured using a 12‐lead electrocardiogram, while the presence of interatrial block (IAB; P ≥ 110 ms) was assessed. Results: There were no significant differences between the two groups regarding age, sex, history of hypertension or diabetes, and hyperlipidemia. Compared to controls, BMI, left atrial diameter (LAD), and interventricular septal thickness were increased, while Pmax (111.9 ± 9.3 vs 101.1 ± 6.0 ms, P < 0.01) and Pd (47.9 ± 9.3 vs 31.8 ± 6.9 ms, P < 0.01) were significantly prolonged in the obese group. Pmin was similar between the two groups. The prevalence of IAB was significantly greater in the obese subjects. Pearson's correlation analysis showed that there were positive correlations between Pd and BMI (r = 0.6, P < 0.001), as well as between Pd and LAD (r = 0.366, P < 0.05). Conclusion: Our data suggest that obesity is associated with increased Pmax and Pd, and increased prevalence of IAB, parameters that have been associated with atrial fibrillation. The correlation of these electrocardiogram parameters with LAD indicates an association between increased BMI and atrial remodeling in Asian subjects. Ann Noninvasive Electrocardiol 2010;15(3):259–263
The Significance of Pulse Oximetry in the Diagnosis of Pacemaker Failure to Output
Authors: Michailidis Athanasios , Barsheshet Alon 
Published: July 2010

In a routine monitor electrocardiogram few hours after implantation of a dual‐chamber pacemaker, there was a suspicion of ventricular oversensing leading to failure to output. Pulse oximeter plethysmographic wave signal virtually excluded this suspicion. This case report demonstrates the clinical utility of initial pulse oximeter wave analysis in excluding pacemaker failure to output. Ann Noninvasive Electrocardiol 2010;15(3):293–295
Usefulness of T‐Wave Alternans in Sudden Death Risk Stratification and Guiding Medical Therapy
Authors: Nieminen Tuomo , Verrier Richard L. 
Published: July 2010

Visible T‐wave alternans (TWA), a beat‐to‐beat alternation in the morphology and amplitude of the ST segment or T wave, has been observed for over a century to occur in association with life‐threatening arrhythmias in patients with acute coronary syndrome, heart failure, and cardiac channelopathies. This compelling linkage prompted development of quantitative techniques leading to FDA‐cleared commercial methodologies for measuring nonvisible levels of TWA in the frequency and time domains. The first aim of this review is to summarize evidence from more than a hundred studies enrolling a total of >12,000 patients that support the predictivity of TWA for cardiovascular mortality and sudden cardiac death.The second focus is on the usefulness of TWA in guiding therapy. Until recently, TWA has been used primarily in decision making for cardioverter‐defibrillator implantation. Its potential utility in guiding pharmacologic therapy has been underappreciated. We review clinical literature supporting the usefulness of TWA as an index of antiarrhythmic effects and proarrhythmia for different drug classes. Beta‐adrenergic and sodium channel‐blocking agents are the most widely studied drugs in clinical TWA investigations, with both reducing TWA magnitude; the exception is patients in whom sodium channel blockade discloses the Brugada syndrome and provokes macroscopic TWA. An intriguing possibility is that TWA may help to detect beneficial effects of nonantiarrhythmic agents such as the angiotensin II receptor blocker valsartan, which indirectly protects from arrhythmia through improving myocardial remodeling. We conclude that quantitative analysis of TWA has considerable potential to guide pharmacologic intervention and thereby serve as a therapeutic target. Ann Noninvasive Electrocardiol 2010;15(3):276–288
Differential Classification of Acute Myocardial Infarction into ST‐ and Non‐ST Segment Elevation Is Not Valid or Rational
Authors: Phibbs Brendan , Nelson William 
Published: July 2010

Background: The distinction between ST elevation and nonST elevation infarcts is widely accepted and is employed as a guide to management. Aim: This is review of the world literature to assess the basis for this distinction, since the two studies on which it is based are seriously flawed in method and conclusions. Method: Pathologic and clinical studies were reviewed from the world literature. Finding: The pathology of the two subsets is identical as are the morbidity, mortality and clinical course. Non‐ST elevation infarcts are likely to be subsequent, to occur in older patients and to involve the circumflex artery: this subset therefore includes a high‐risk group. ST deviation in any part of the electric field of the heart will predictably be accompanied by reciprocal deviation if the entire field of the heart is mapped. Further, ST deviation of infarction is often transient, resolving in minutes so that infarcts will be predictably misclassified. ST deviation per se is therefore not a rational basis for classification of infarcts. In fact, invasive therapy is indicated in both subsets with identical results. Conclusion: The distinction between ST elevation and non‐ST elevation infarcts is baseless. The high risk subgroup included in the non‐ST elevation infarct set should not be denied the benefit of early invasive therapy. Ann Noninvasive Electrocardiol 2010;15(3):191–199
Telocytes in human epicardium
Authors: Popescu L. M. , Manole C. G. , Gherghiceanu M. , Ardelean A. , Nicolescu M. I. , Hinescu M. E. , Kostin S. 
Published: July 2010

AbstractThe existence of the epicardial telocytes was previously documented by immunohistochemistry (IHC) or immunofluorescence. We have also demonstrated recently that telocytes are present in mice epicardium, within the cardiac stem‐cell niches, and, possibly, they are acting as nurse cells for the cardiomyocyte progenitors. The rationale of this study was to show that telocytes do exist in human (sub)epicardium, too. Human autopsy hearts from 10 adults and 15 foetuses were used for conventional IHC for c‐kit/CD117, CD34, vimentin, S‐100, τ, Neurokinin 1, as well as using laser confocal microscopy. Tissue samples obtained by surgical biopsies from 10 adults were studied by digital transmission electron microscopy (TEM). Double immunolabelling for c‐kit/CD34 and, for c‐kit/vimentin suggests that in human beings, epicardial telocytes share similar immunophenotype features with myocardial telocytes. The presence of the telocytes in human epicardium is shown by TEM. Epicardial telocytes, like any of the telocytes are defined by telopodes, their cell prolongations, which are very long (several tens of μm), very thin (0.1–0.2 μm, below the resolving power of light microscopy) and with moniliform configuration. The interconnected epicardial telocytes create a 3D cellular network, connected with the 3D network of myocardial telocytes. TEM documented that telocytes release shed microvesicles or exocytotic multivesicular bodies in the intercellular space. The human epicardial telocytes have similar phenotype (TEM and IHC) with telocytes located among human working cardiomyocyte. It remains to be established the role(s) of telocytes in cardiac renewing/repair/regeneration processes, and also the pathological aspects induced by their ‘functional inhibition’, or by their variation in number. We consider telocytes as a real candidate for future developments of autologous cell‐based therapy in heart diseases.
Cobalt release from inexpensive jewellery: has the use of cobalt replaced nickel following regulatory intervention?
Authors: Thyssen Jacob Pontoppidan , Jellesen Morten S. , Menné Torkil , Lidén Carola , Julander Anneli , Møller Per , Johansen Jeanne Duus 
Published: July 2010

Background: Before the introduction of the EU Nickel Directive, concern was raised that manufacturers of jewellery might turn from the use of nickel to cobalt following the regulatory intervention on nickel exposure. Objectives: The aim was to study 354 consumer items using the cobalt spot test. Cobalt release was assessed to obtain a risk estimate of cobalt allergy and dermatitis in consumers who would wear the jewellery. Methods: The cobalt spot test was used to assess cobalt release from all items. Microstructural characterization was made using scanning electron microscope (SEM) and energy‐dispersive spectroscopy (EDS). Results: Cobalt release was found in 4 (1.1%) of 354 items. All these had a dark appearance. SEM/EDS was performed on the four dark appearing items which showed tin–cobalt plating on these. Conclusions: This study showed that only a minority of inexpensive jewellery purchased in Denmark released cobalt when analysed with the cobalt spot test. As fashion trends fluctuate and we found cobalt release from dark appearing jewellery, cobalt release from consumer items should be monitored in the future. Industries may not be fully aware of the potential cobalt allergy problem.
Methylisothiazolinone, an emerging allergen in cosmetics?
Authors: García‐Gavín Juan , Vansina Sara , Kerre Stefan , Naert Alix , Goossens An 
Published: July 2010

Background: A few cases on primary sensitization by, and occupational contact dermatitis from, methylisothiazolinone in paints and glues have been published. In cosmetics, methylisothiazoline (MI) is permitted in a concentration of 100 p.p.m., while 15 p.p.m. for the mixture of methylchloroisothiazolinone and methylisothiazoline (MCI/MI). Objectives: To present cases of sensitization to, and allergic contact dermatitis from, cosmetic products containing methylisothiazolinone only. Patients, Materials, and Methods: Seven patients with suspected contact dermatitis – six of them with (peri‐)anal lesions and one with facial dermatitis – were patch tested with the baseline series, the own products exposed to, cosmetic ingredients, as well as with methylisothiazolinone 1000 p.p.m. and MCI/MI 200 p.p.m. Results: The patients with anal lesions had become sensitized by wipes for intimate hygiene, and one patient with facial dermatitis by a make‐up remover, all containing methylisothiazolinone only. Three out of seven cases would have been missed if only MCI/MI 100 p.p.m., as present in the baseline series, had been tested. Conclusion: The inclusion of methylisothiazolinone as a preservative in cosmetics might not represent the solution to the problem of allergic contact dermatitis from isothiazolinones, since it leads to primary sensitization.
The effect of diabetes mellitus on rat mandibular bone formation and microarchitecture
Authors: Abbassy Mona A. , Watari Ippei , Soma Kunimichi 
Published: July 2010

Abbassy MA, Watari I, Soma K. The effect of diabetes mellitus on rat mandibular bone formation and microarchitecture. Eur J Oral Sci 2010; 118: 364–369. © 2010 The Authors. Journal compilation © 2010 Eur J Oral Sci The aim of this study was to assess the effect of type 1 diabetes mellitus (DM) on the structure of mandibular bone and on the changes of alveolar/jaw bone formation. Experimental DM was induced in 3‐wk‐old male Wistar rats by a single dose of 60 mg/kg body weight of streptozotocin. All rats were injected with calcein on days 21 and 28. The rats were killed when 8 wk of age. Bone structure was analyzed by bone histomorphometry, microcomputed tomography (micro‐CT), and histological section. Histomorphometric analysis showed that the mineral apposition and the bone formation rates in most of the mandibular regions were significantly decreased in the DM group compared with the control group. Micro‐CT analysis showed significant deterioration of the bone quality in rats with DM. For a histometric measure of bone resorption, the number of osteoclasts along the distal surface of the alveolar wall was counted. The number of osteoclasts was significantly lower in the rats with DM than in the controls. These findings suggest that uncontrolled DM decreases mandibular bone formation, reduces the rate of bone turnover in the alveolar wall surrounding the root, and affects the quality of bone structure resulting in retardation of its skeletal development.
CRISPLD2 polymorphisms are associated with non‐syndromic cleft lip with or without cleft palate in a northern Chinese population
Authors: Shi Jinna , Jiao Xiaohui , Song Tao , Zhang Bing , Qin Chunlin , Cao Fenglin 
Published: July 2010

Shi J, Jiao X, Song T, Zhang B, Qin C, Cao F. CRISPLD2 polymorphisms are associated with non‐syndromic cleft lip with or without cleft palate in a northern Chinese population. Eur J Oral Sci 2010; 118: 430–433. © 2010 The Authors. Journal compilation © 2010 Eur J Oral SciNon‐syndromic cleft lip with or without cleft palate (NSCLP) is the most common craniofacial birth defect. This complex genetic disorder results from interactions between genes and environmental factors. Numerous genes have been reported in studies demonstrating association between the cleft lip and palate phenotypes and the alleles at single‐nucleotide polymorphisms (SNPs) within specific genes. Recently, the cysteine‐rich secretory protein LCCL domain containing 2 (CRISPLD2) has been revealed to be a novel candidate gene for NSCLP. The SNPs rs1546124, rs4783099 and rs16974880 in CRISPLD2 were highly significant in Caucasian and Hispanic multiplex families but showed no association in Colombian and Irish populations. In the current study, we examined these three SNPs in a northern Chinese population and found an association between these polymorphisms and NSCLP in both single‐marker and haplotype analyses. Our data further strengthen the conclusion that altered CRISPLD2 is associated with NSCLP susceptibility.
Low‐fluoride toothpaste and deciduous enamel demineralization under biofilm accumulation and sucrose exposure
Authors: Cury Jaime A. , Do Amaral Regiane C. , Tenuta Livia M. A. , Del Bel Cury Altair A. , Tabchoury Cínthia P. M. 
Published: July 2010

Cury JA, do Amaral RC, Tenuta LMA, Del Bel Cury AA, Tabchoury CPM. Low‐fluoride toothpaste and deciduous enamel demineralization under biofilm accumulation and sucrose exposure. Eur J Oral Sci 2010; 118: 370–375. © 2010 The Authors. Journal compilation © 2010 Eur J Oral Sci Because low‐fluoride toothpaste (500 p.p.m. F) has not clearly been shown to be effective for controlling caries in caries‐active children, this experimental in situ study was conducted to evaluate whether its effect, when compared with a conventional toothpaste (1,000–1,500 p.p.m. F), would depend on the cariogenic challenge. During four phases of 14 d each, 14 volunteers used 500 or 1,100 p.p.m. F toothpaste and wore palatal appliances containing deciduous enamel slabs, on which biofilm was accumulated and exposed to 20% sucrose solution at frequencies increasing from two to eight times per day. The F concentration was determined in the biofilm formed, and enamel demineralization was assessed by surface hardness loss (%SHL) and integrated area of hardness × lesion depth (ΔS). The F uptake by enamel was also determined. Fluoride in biofilm fluid and solids was statistically higher when conventional F toothpaste was used. The toothpastes did not differ statistically in terms of %SHL, ΔS, and F in enamel, but only the conventional F toothpaste significantly reduced caries‐lesion progression according to the frequency of sucrose exposure. The findings suggest that the high‐F availability in biofilm, resulting from the use of conventional toothpaste compared with low‐F toothpaste, may be important for reducing caries‐lesion progression in conjunction with a high frequency of sucrose exposure.
Sodium bicarbonate solution as an anti‐erosive agent against simulated endogenous erosion
Authors: Messias Danielle C. F. , Turssi Cecilia P. , Hara Anderson T. , Serra Mônica C. 
Published: July 2010

Messias DCF, Turssi CP, Hara AT, Serra MC. Sodium bicarbonate solution as an anti‐erosive agent against simulated endogenous erosion. Eur J Oral Sci 2010; 118: 385–388. © 2010 The Authors. Journal compilation © 2010 Eur J Oral Sci This study investigated whether sodium bicarbonate solution, applied on enamel previously exposed to a simulated intrinsic acid, can control dental erosion. Volunteers wore palatal devices containing enamel slabs, which were exposed twice daily extra‐orally to hydrochloric acid (0.01 M, pH 2) for 2 min. Immediately afterwards, the palatal devices were re‐inserted in the mouth and volunteers rinsed their oral cavity with a sodium bicarbonate solution or deionized water for 60 s. After the washout period, the palatal devices were refilled with a new set of specimens and participants were crossed over to receive the alternate rinse solution. The surface loss and surface microhardness (SMH) of specimens were assessed. The surface loss of eroded enamel rinsed with a sodium bicarbonate solution was significantly lower than the surface loss of eroded enamel rinsed with deionized water. There were no differences between treatments with sodium bicarbonate and deionized water for SMH measurements. Regardless of the solution used as an oral rinse, eroded enamel showed lower SMH than uneroded specimens. Rinsing with a sodium bicarbonate solution after simulated endogenous erosive challenge controlled enamel surface loss but did not alter the microhardness.