bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid polypeptides: Gabapentin as a stereochemically constrained γ‐amino acid residue
Authors: Balaram Padmanabhan 
Published: August 2010

AbstractThe design of folded structures in peptides containing the higher homologues of α‐amino acid residues requires the restriction of the range of local conformational choices. In α‐amino acids stereochemically constrained residues like α,α‐dialkylated residue, aminoisobutyric acid (Aib), and D‐Proline (DPro) have proved extremely useful in the design of helices and hairpins in short peptides. Extending this approach, backbone substitution and cyclization are anticipated to be useful in generating conformationally constrained β‐ and γ‐residues. This brief review provides a survey of work on hybrid peptide sequences concerning the conformationally constrained γ‐amino acid residue 1‐aminomethyl cyclohexane acetic acid, gabapentin (Gpn). This achiral, β,β‐disubstituted, γ‐residue strongly favors gauche‐gauche conformations about the Cα‐Cβ (θ2) and Cβ‐Cγ (θ1) bonds, facilitating local folding. The Gpn residue can adopt both C7 (NHi→COi) and C9 (COi‐1←NHi+1) hydrogen bonds which are analogous to the C5 and C7 (γ‐turn) conformations at α‐residues. In conjunction with adjacent residues, Gpn may be used in αγ and γα segments to generate C12 hydrogen bonded conformations which may be considered as expanded analogs of conventional β‐turns. The structural characterization of C12 helices, C12/C10 helices with mixed hydrogen bond directionalities and β‐hairpins incorporating Gpn residues at the turn segment is illustrated. © 2010 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 94: 733–741, 2010.This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Biomass production of hairy roots of Artemisia annua and Arachis hypogaea in a scaled‐up mist bioreactor
Authors: Sivakumar Ganapathy , Liu Chunzhao , Towler Melissa J. , Weathers Pamela J. 
Published: August 2010

AbstractHairy roots have the potential to produce a variety of valuable small and large molecules. The mist reactor is a gas phase bioreactor that has shown promise for low‐cost culture of hairy roots. Using a newer, disposable culture bag, mist reactor performance was studied with two species, Artemisia annua L. and Arachis hypogaea (peanut), at scales from 1 to 20 L. Both species of hairy roots when grown at 1 L in the mist reactor showed growth rates that surpassed that in shake flasks. From the information gleaned at 1 L, Arachis was scaled further to 4 and then 20 L. Misting duty cycle, culture medium flow rate, and timing of when flow rate was increased were varied. In a mist reactor increasing the misting cycle or increasing the medium flow rate are the two alternatives for increased delivery of liquid nutrients to the root bed. Longer misting cycles beyond 2–3 min were generally deemed detrimental to growth. On the other hand, increasing the medium flow rate to the sonic nozzle especially during the exponential phase of root growth (weeks 2–3) was the most important factor for increasing growth rates and biomass yields in the 20 L reactors. A. hypogaea growth in 1 L reactors was µ = 0.173 day−1 with biomass yield of 12.75 g DW L−1. This exceeded that in shake flasks at µ = 0.166 day−1 and 11.10 g DW L−1. Best growth rate and biomass yield at 20 L was µ = 0.147 and 7.77 g DW L−1, which was mainly achieved when medium flow rate delivery was increased. The mist deposition model was further evaluated using this newer reactor design and when the apparent thickness of roots (+hairs) was taken into account, the empirical data correlated with model predictions. Together these results establish the most important conditions to explore for future optimization of the mist bioreactor for culture of hairy roots. Biotechnol. Bioeng. 2010;107: 802–813. © 2010 Wiley Periodicals, Inc.
Feigning in adjudicative competence evaluations
Authors: Soliman Sherif , Resnick Phillip J. 
Published: August 2010

AbstractCompetence to stand trial (adjudicative competence) is the most requested forensic psychiatric evaluation, with an estimated 60,000 referrals annually. The challenge of detecting feigned incompetence has not been systematically studied until the past decade. Estimates of feigned adjudicative incompetence vary from 8 to 21%. This article reviews techniques for detecting malingered psychosis and malingered cognitive impairment during competence evaluations. Specific techniques for assessing feigned adjudicative incompetence and estimating the malingerer's genuine abilities are discussed. A stepwise approach to suspected feigned adjudicative incompetence is proffered. Copyright © 2010 John Wiley & Sons, Ltd.
Structural and Electronic Effects of Carbon‐Supported PtxPd1−xNanoparticles on the Electrocatalytic Activity of the Oxygen‐Reduction Reaction and on Methanol Tolerance
Authors: Chang Shih‐Hong , Su Wei‐Nien , Yeh Min‐Hsin , Pan Chun‐Jern , Yu Kuan‐Li , Liu Din‐Goa , Lee Jyh‐Fu , Hwang Bing‐Joe 
Published: August 2010

AbstractWe report a systematic investigation on the structural and electronic effects of carbon‐supported PtxPd1−xbimetallic nanoparticles on the oxygen reduction reaction (ORR) and methanol oxidation reaction (MOR) in acid electrolyte. PtxPd1−x/C nanocatalysts with various Pt/Pd atomic ratios (x=0.25, 0.5, and 0.75) were synthesized by using a borohydride‐reduction method. Rotating‐disk electrode measurements revealed that the Pt3Pd1/C nanocatalyst has a synergistic effect on the ORR, showing 50 % enhancement, and an antagonistic effect on the MOR, showing 90 % reduction, relative to JM 20 Pt/C on a mass basis. The extent of alloying and Pt d‐band vacancies of the PtxPd1−x/C nanocatalysts were explored by extended X‐ray absorption fine‐structure spectroscopy (EXAFS) and X‐ray absorption near‐edge structure spectroscopy (XANES). The structure–activity relationship indicates that ORR activity and methanol tolerance of the nanocatalysts strongly depend on their extent of alloying and d‐band vacancies. The optimal composition for enhanced ORR activity is Pt3Pd1/C, with high extent of alloying and low Pt d‐band vacancies, owing to favorable OO scission and inhibited formation of oxygenated intermediates. MOR activity also shows structure dependence. For example, Pt1Pd3/C with Ptrich−corePdrich−shellstructure possesses lower MOR activity than the Pt3Pd1/C nanocatalyst with random alloy structure. Herein, extent of alloying and d‐band vacancies reveal new insights into the synergistic and antagonistic effects of the PtxPd1−x/C nanocatalysts on surface reactivity.
Pt–NiCo Nanostructures with Facilitated Electrocatalytic Activities for Sensitive Determination of Intracellular Thiols with Long‐Term Stability
Authors: Zhang Feng , Wen Ming , Cheng Mingzhu , Liu Di , Zhu Anwei , Tian Yang 
Published: August 2010

AbstractA Pt–NiCo nanomaterial has been synthesized for developing the sensitive electrochemical determination of biological thiols that include L‐cysteine (CySH), homocysteine (HCySH), and gluthione (GSH) with high sensitivity and long‐term stability, in which the Pt nanoparticles are well supported on amorphous NiCo nanofilms. The electrochemical oxidation of thiols has been successfully facilitated on the optimized Pt–NiCo nanostructures, that is, two oxidation peaks of CySH have been clearly observed at potentials of +0.06 and +0.45 V. The experimental results demonstrate that the first peak for CySH oxidation may be attributed to a direct oxidation from CySH to L‐cystine (CySSCy), whereas the second peak possibly results from a sequential oxidation from CySSCy to cysteic acid (CySO3H), together with a direct oxidation of CySH into CySO3H. The enhanced electrocatalytic activities at the Pt23–NiCo nanostructures have provided a methodology to determine thiols at a very low potential of 0.0 V with relatively high sensitivity (637 nA μM cm−2), a low detection limit (20 nM), and a broad linear range. The striking analytical performance, together with the characteristic properties of the Pt–NiCo nanomaterial itself, including long‐term stability and strong antipoisoning ability, has established a reliable and durable approach for the detection of thiols in liver cancer cells, Hep G2.
Synthetic Studies on and Mechanistic Insight into [W(CO)5(L)]‐Catalyzed Stereoselective Construction of Functionalized Bicyclo[5.3.0]decane Frameworks
Authors: Onizawa Yuji , Hara Masahiro , Hashimoto Takuya , Kusama Hiroyuki , Iwasawa Nobuharu 
Published: August 2010

AbstractStereoselective preparation of a variety of synthetically useful functionalized bicyclo[5.3.0]decane derivatives was achieved by tandem cyclization of 3‐siloxy‐1,3,9‐triene‐7‐yne derivatives based on the electrophilic activation of alkynes catalyzed by [W(CO)5(L)]. The reaction proceeded smoothly under photoirradiation, and various substrates were cyclized to give the corresponding bicyclic compounds with up to four chiral centers stereospecifically. Reactions of siloxydienes with a silyl substituent as an equivalent of a hydroxyl group also proceeded with wide generality to afford silyl‐substituted bicyclo[5.3.0]decanes, which were highly useful as synthetic intermediates. Stereochemical studies concerning the silyl enol ether moiety suggested that two types of reaction pathway for the formation of seven‐membered rings were present. The reaction of (Z)‐enol silyl ethers proceeded through Cope rearrangement of cis‐divinylcyclopropane intermediates, and that of (E)‐enol silyl ethers by 1,4‐addition of the dienyl tungsten species at the position δ to the metal atom. In the reactions of siloxydiene derivatives with silyl substituents, all possible diastereomers could be synthesized stereoselectively by changing the geometry of the silyl enol ether and enyne moieties.
ChemInform Abstract: Highly Oriented Molecular Ag Nanocrystal Arrays.
Authors: HARFENIST S. A. , WANG Z. L. , ALVAREZ M. M. , VEZMAR I. , WHETTEN R. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal Structure of Some Rhenium and Technetium Dichalcogenides.
Authors: LAMFERS H.‐J. , MEETSMA A. , WIEGERS G. A. , DE BOER J. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Effect of Fe Substitution on the Magnetic and Electrical Properties of the (Bi1.6Pb0.4) (Sr1.8Ba0.2)Ca2 (Cu1‐xFex)3Oy Superconductor.
Authors: POP A. V. , ILONCA GH. , CIURCHEA D. , YE M. , GERU I. I. , KANTSER V. G. , POP V. , TODICA M. , DELTOUR R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Transition in TbMn2Si2.
Authors: KOLENDA M. , LECIEJEWICZ J. , SZYTULA A. , STUESSER N. , TOMKOWICZ Z. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure‐Property Relationships in a Series of Mixed Layer Pnictide Oxide Compounds: A2Mn3Pn2O2 (A: Sr, Ba; Pn: P, As, Sb).
Authors: BROCK S. L. , KAUZLARICH S. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrodeposition of Indium Selenide In2Se3.
Authors: MASSACCESI S. , SANCHEZ S. , VEDEL J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Barium Germanium Nitride, Ba3Ge2N2, Containing 1∞(Ge2‐) and GeN4‐2 Anions.
Authors: YAMANE H. , DISALVO F. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Actinoid Nickel Phosphides Th11Ni25P20 and U11Ni25P20.
Authors: ALBERING J. H. , JEITSCHKO W. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Properties of NbM2LnCu2O8 and TaM2LnCu2O8 Phases (M: Ba, Sr; Ln: Pr, Nd, Sm, Eu and Gd).
Authors: KOPNIN E. M. , LOBANOV M. V. , ABAKUMOV A. M. , LUBARSKII S. V. , LEBEDEV O. I. , ANTIPOV E. V. , CAPPONI J. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanism of Lithiation of Hydric Aromatics: Direct NMR Evidence for Short H‐Li Contacts in Mixed Aggregates.
Authors: SAA. J. M. SAA. J. M. , MARTORELL G. , FRONTERA A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stability‐Reactivity Relation on the Reaction of β,β‐ Disubstituted Vinyl Cations with Ethanol.
Authors: KOBAYASHI S. , HORI Y. , HASAKO T. , KOGA K. , YAMATAKA H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Peculiarities of Alkaline Hydrolysis and Alcoholysis of N‐( Arylsulfonylamido)‐ and N‐(N′‐Acetylarylsulfonylamido)succin‐ and ‐ glutarimides
Authors: SHEMCHUK L. A. , CHERNYKH V. P. , GRITSENKO I. S. , GORYACHII V. D. , IVANOVA I. L. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New Imidazo(4,5‐d)(1,3)diazepine Derivatives from 5‐Amino‐ 4‐(cyanoformimidoyl)imidazoles.
Authors: DIAS A. M. , PROENCA M. F. J. R. P. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hypervalent Ammonium Radicals. Effects of Alkyl Groups and Aromatic Substituents.
Authors: SHAFFER S. A. , SADILEK M. , TURECEK F. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Functionalization of Saturated Hydrocarbons by Aprotic Superacids. Part 4. Ionic Bromination of Ethane, Other Alkanes, and Cycloalkanes with Molecular Bromine in the Presence of Polyhalomethane‐AlBr3 Systems Under Mild Conditions.
Authors: AKHREM I. S. , ORLINKOV A. V. , AFANAS'EVA L. V. , VOL'PIN M. E. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chloroarylation of Unsaturated Compounds with 4,4′‐Bisdiazonium‐3,3′‐ dichlorodiphenylmethane Dichloride.
Authors: FEDOROVICH I. S. , OBUSHAK N. D. , LYAKHOVICH M. B. , GANUSHCHAK N. I. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intramolecular and Intermolecular Mn(III)‐Induced Carbon Monoxide Trapping Reactions of Alkynes with Malonate and Cyano Ester Units.
Authors: OKURA K. , ALPER H. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Functionalization of Saturated Hydrocarbons by Aprotic Superacids. Part 5. Regioselective Carbonylation of Propane in Organic Solvent Initiated by the Aprotic Organic Superacids CX4×nAlBr3 (X: Br, Cl; n = 1 or 2)
Authors: AKHREM I. S. , ORLINKOV A. V. , AFANAS'EVA L. V. , VOL'PIN M. E. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Anomalously Stable C‐Methoxycarbonyl‐N‐(p‐nitrophenyl) nitrone.
Authors: DIL'MAN A. D. , LYAPKALO I. M. , IOFFE S. L. , STRELENKO YU. A. , TARTAKOVSKII V. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Chemical Reactions of α‐Cyano‐α‐ isocyanoalkanoic Acids.
Authors: BERGEMANN M. , NEIDLEIN R. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Vinyl‐1,1,2‐trihalocyclopropanes ‐ Valuable Five Carbon Cyclopropane and Cyclopropene Synthetic Intermediates.
Authors: AL DULAYYMI A. R. , BAIRD M. S. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Use of Carbopalladation of Allenes in the Synthesis of Polycyclic Compounds. A Rapid Access to Steroid Skeletons.
Authors: GAUTHIER V. , CAZES B. , GORE J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐Alkoxy‐2,5‐dioxo‐4,4‐bis(trifluoromethyl)‐6,7‐benzo‐1,3,2‐ dioxaphosphepanes in the Synthesis of Substituted Fluorinated Ketones.
Authors: MIRONOV V. F. , KONOVALOVA I. V. , BURNAEVA L. M. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: α‐(Benzotriazolyl)methyl Phenyl Thioethers: Convenient Reagents for α‐Phenylthioalkylation of Silylated Nucleophiles.
Authors: KATRITZKY A. R. , CHEN J. , BELYAKOV S. A. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biological Activity of Water‐Soluble Fullerenes. Structural Dependence of DNA Cleavage, Cytotoxicity, and Enzyme Inhibitory Activities Including HIV‐Protease Inhibition.
Authors: NAKAMURA E. , TOKUYAMA H. , YAMAGO S. , SHIRAKI T. , SUGIURA Y. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemoselective Synthesis and Resolution of Chiral (1,9) Methanofullerene(70) Derivatives.
Authors: WANG Y. , SCHUSTER D. I. , WILSON S. R. , WELCH C. J. 
Published: August 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.