bluuebunny/crossref_metadata_2025_split huggingface dataset:
Far visual acuity is unremarkable in autism: Do we need to focus on crowding?
Authors: Kéïta Luc , Mottron Laurent , Bertone Armando 
Published: October 2010

AbstractAlthough autism presents a unique perceptual phenotype defined in part by atypical (often enhanced) analysis of spatial information, few biologically plausible hypotheses have been advanced to explain its neural underpinnings. One plausible explanation is functional but altered lateral connectivity mediating early or local mechanisms selectively responsive to different stimulus attributes, including spatial frequency and contrast. The goal of the present study was first to assess far visual acuity in autism using Landolt‐C optotypes defined by different local stimulus attributes. Second, we investigated whether acuity is differentially affected in autism when target optotypes are simultaneously presented with flanking stimuli at different distances. This typical detrimental “crowding effect” of flanking stimuli on target optotype discrimination is attributed to lateral inhibitory interaction of neurons encoding for visual properties of distracters close to the target. Results failed to demonstrate a between‐group difference in acuity to Landolt‐C optotypes, whether defined by luminance‐ or texture‐contrast. However, the expected crowding effect at one gap‐size opening distance was evidenced for the control group only; a small effect was observed for the autism group at two gap‐size opening. These results suggest that although far visual acuity is unremarkable in autism, altered local lateral connectivity within early perceptual areas underlying spatial information processing in autism is atypical. Altered local lateral connectivity in autism might originate from an imbalance in excitatory/inhibitory neural signaling, resulting in changes regarding elementary feature extraction and subsequent downstream visual integration and visuo‐spatial analysis. This notion is discussed within the context of characteristic lower‐ and higher‐level perceptual processing in autism.
The role of Embeddedness in Industrial Symbiosis Networks: Phases in the Evolution of Industrial Symbiosis Networks
Authors: Doménech Teresa , Davies Michael 
Published: October 2010

ABSTRACTIndustrial symbiosis (IS) has emerged as a body of exchange structures to progress to a more eco‐efficient industrial system, by establishing a collaborative web of knowledge, material and energy exchanges among different organizational units. However, even given the potential economic and environmental benefits derived from IS networks, the process of emergence and development of these networks seems far from straightforward. The effective operation of such networks relies heavily on aspects such as trust and general reciprocity, aspects insufficiently covered in the IS literature. Based on the theoretical framework provided by social network analysis and economic geography and the empirical data collected through qualitative methods, based on the approach of Grounded Theory, the authors propose a modelling framework to analyse the main mechanisms in the building of trust and embeddedness and identify different phases in cooperation leading to effective IS exchanges. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Message strength and persuasion when consumers imagine product usage
Authors: Praxmarer Sandra 
Published: October 2010

AbstractThis paper analyzes the effects of message strength on brand attitude when consumers simulate product usage. The relevant literature suggests that advertising message strength does not matter when consumers imagine product usage, but previous studies do not consider the potential moderating effects of involvement and product category knowledge. The results of this research demonstrate that among high‐involvement consumers who perceive their knowledge in the product category as limited, imagining product usage does not reduce the relevance of a strong advertising message. This paper also shows that overall, imagining product usage positively affects brand attitude – regardless of message strength, involvement, and self‐perceived knowledge. An important practical implication arises from the study. Marketers should encourage mental simulation in their advertisements, but be careful not to set a good argument aside if the product/service is highly relevant to potential customers and the potential customers do not perceive themselves as very knowledgeable about the product category. This finding is particularly relevant to complex or relatively new products, because here, the group of consumers who are highly involved but do not perceive themselves as very knowledgeable may be large. Copyright © 2010 John Wiley & Sons, Ltd.
Complications associated with left ventricular puncture
Authors: Pitta Sridevi R. , Cabalka Allison K. , Rihal Charanjit S. 
Published: October 2010

AbstractObjective: To report complications in a consecutive series of patients undergoing percutaneous left ventricular apical puncture (LVAP) and sheath placement for diagnostic or interventional procedures. Background: Percutaneous LVAP is only rarely used to provide hemodynamic data in the presence of mechanical prosthetic valves. Recently, LVAP has been used to facilitate complex interventional procedures such as paravalvular leak closures. These frequently necessitate placement of 4–6 F sheaths, rather than smaller needles. Optimal technique and outcomes are largely unknown for this uncommon procedure. Methods: We retrospectively analyzed 32 patients undergoing LVAP with echocardiographic and fluoroscopic guidance at our institution between 2002 and 2009. These patients were referred to the cardiac catheterization laboratory for hemodynamic assessment to rule out prosthetic dysfunction and or to facilitate paravalvular leak closure. Sheaths ranged from 4 to 6 F were removed at the end of the procedure after reversing any anticoagulation. No specific closure devices were used for hemostasis. Frequency of access site complications associated with LVAP recorded. Results: Apical access site related complications were higher in patients requiring LVAP for intervention than for diagnostic purposes (25% vs. 12.5%). Hemothorax was the most frequent serious complication occurring in 6 (19%) patients and frequently required intervention 5(16%). Three patients had local bleeding with no drop in hemoglobin or need for intervention. Conclusions: LVAP is associated with a significant incidence of access‐related complications. There is a need for safe and reliable methods of closing percutaneous LVAP access sites. © 2010 Wiley‐Liss, Inc.
Transcatheter closure of perimembranous ventricular septal defect in children: Safety and efficiency with symmetric and asymmetric occluders
Authors: Yang Rong , Sheng Yanhui , Cao Kejiang , Kong Xiangqing , Xu Di , Yong Yonghong , Zhou Lei , Zhang Hao , Qian Linmei , Sun Wei , Gu Zhengnan 
Published: October 2010

AbstractObjectives: This study was designed to determine the safety and efficiency of asymmetric and symmetric ventricular septal occluders (AVSDOs and SVSDOs, respectively) for closure perimembranous ventricular septal defect (PMVSD) in children. Methods: Between January 2003 and December 2007, 142 children with PMVSD were treated with occluders (64 with AVSDOs and 78 with SVSDOs). Results: The defect diameter was 5.3 ± 1.1 mm in the AVSDO group and 5.4 ± 1.3 mm in the SVSDO group (P > 0.05). The success rates were similar between two groups [93.8% (AVSDO) vs. 94.9% (SVSDO), P > 0.05]. Two patients in the AVSDO group were switched to the SVSDO group due to residual shunts, and one patient in the SVSDO group was switched due to aortic regurgitation after deployment of the occluder. After procedure, 17 patients [seven with AVSDOs and nine with SVSDOs (P > 0.05)] developed various types of heart block (HB). Among them, 13 patients converted to the normal sinus rhythm. The remaining four cases had not recovered at the end of the study. Conclusions: Transcatheter closure of PMVSD using both AVSDO and SVSDO was safe and effective. Development of HB was the main complication for both devices. © 2010 Wiley‐Liss, Inc.
A Switch‐On Fluorescence Assay for Bacterial β‐Lactamases with Amyloid Fibrils as Fluorescence Enhancer and Visual Tool
Authors: Zou Lan , Cheong Wing‐Lam , Chung Wai‐Hong , Leung Yun‐Chung , Wong Kwok‐Yin , Wong Man‐Kin , Chan Pak‐Ho 
Published: October 2010

AbstractHerein is described the development of a novel switch‐on fluorescence assay for detecting β‐lactamases. The fluorescence assay comprises two components: solid beads coated with a β‐lactam antibiotic, which is linked to an environment‐sensitive fluorophore (dansylaminothiophenol, DTA), and amyloid fibrils of hen lysozyme (acting as fluorescence enhancer and visual tool). In the presence of the clinically significant TEM‐1 β‐lactamase, the DTA–antibiotic complex on the solid beads is hydrolyzed, thus releasing the DTA dye into solution. The DTA dye is only weakly fluorescent in solution but gives strong green fluorescence upon binding to lysozyme fibrils. These strongly fluorescent DTA‐bound fibrils can be easily visualized by the naked eye upon illumination of the sample with a simple UV lamp. The fluorescence assay can detect TEM‐1 at low concentration (0.01 nM). In contrast, no observable fluorescence appears when the fluorescence assay is performed on samples without the TEM‐1 β‐lactamase.
Theoretical elucidation on the functional role of pyrrolidine‐type ionic liquids in inducing stereoselectivity of the Michael addition of cyclohexanone with trans‐β‐nitrostyrene
Authors: Sun Hui , Zhang Dongju 
Published: October 2010

AbstractDensity functional theory calculations have been carried out to elucidate the stereoselectivity of the Michael addition of cyclohexanone with trans‐β‐nitrostyrene, induced by a chiral ionic liquid (CIL) pyrrolidine‐imidazolium bromide. By comparison of the CC bond forming processes in the absence and presence of Br− anion, we found that intermolecular H‐bonds between the imidazolium cation and the nitro group of trans‐β‐nitrostyrene and the steric hindrance of the imidazolium cation moiety on the Si‐face of enamine dominate the stereoselectivity of the Michael addition. The presence of Br− anion obviously reduces the barrier by increasing the polarity of the C4C5 bond of enamine. The theoretical results rationalize well the early experimental finding, and reveal a valuable clue for the further CIL design with high catalytic efficiency. Chirality, 2011. © 2010 Wiley‐Liss, Inc.
Optical activity and Alfred Werner's coordination chemistry
Authors: Ernst Karl‐Heinz , Berke Heinz 
Published: October 2010

AbstractIt is widely accepted, that Pasteur's seminal discovery of the opposite optical activity of ammonium sodium tartrate enantiomorphs in solution gave the spark to organic stereochemistry and led to the development of the tetrahedron model by van't Hoff and Le Bel. The proof that chirality is inherently connected to octahedral coordination chemistry fostered greatly Werner's spatial views of metal complexes and his coordination theory. The actual proof of principle was established via separation of diastereomeric camphor sulfonate salts of racemic metal complexes. Chirality, 2011. © 2010 Wiley‐Liss, Inc.
Enantiomer self‐disproportionation and chiral stationary phase based selective chiral separation of organic compounds
Authors: Mayani Vishal J. , Abdi Sayed H. R. , Mayani Suranjana V. , Kim Heon‐Chang , Park Seung‐Kyu 
Published: October 2010

AbstractIn modern chromatography, chiral stationary phase (CSP) and enantiomer self‐disproportionation (ESD) are new inventions of packing material offer a guarantee for a successful enantiomeric separation. All CSPs were synthesized by chemical bonding of the relevant organic moieties onto a porous parent silica material for the separation of various racemic mixtures whereas achiral silica matrix was used for separation of non‐racemic mixtures in ESD. Our present study provides to establish an understanding on the entire enantio‐selective profile of amino alcohol based CSP as well as ESD and their precise utilization for high success ratesfor selective enantiomer separation with its appropriateness. Chirality, 2011. © 2010 Wiley‐Liss, Inc.
Das Gesetz vom Minimum. Liebig oder Sprengel?
Authors: Gröger Martin 
Published: October 2010

AbstractZu Beginn des 19. Jahrhunderts vollzog sich langsam der Wandel von der Humustheorie zur Mineralstofflehre. Carl Sprengel kann als Wegbereiter der neuen Lehre angesehen werden, deren Grundlagen er als erster klar formulierte. Doch erst Justus von Liebig verhalf der Mineralstofflehre zum Durchbruch. So hat Sprengel auch bereits 1828 das Gesetz vom Minimum formuliert, welches heute noch häufig dem populäreren Liebig zugeschrieben wird. Die bekannte Analogie zur Visualisierung des Gesetzes als Minimum‐Tonne geht auf keinen der beiden Protagonisten zurück. Diese Analogie hat sich seit 1903 behauptet, obwohl es bereits 1910 einen Wettbewerb zur Entwicklung einer besseren Darstellung gab.
Die Quadratur des Kohlenstoffs
Authors: Groß Michael 
Published: October 2010

AbstractIst Cyclobutadien quadratisch oder rechteckig? Mehrere Jahrzehnte nach der ersten Synthese des anti‐aromatischen, extrem instabilen Rings aus vier Kohlenstoffatomen hat eine Kristallstrukturanalyse des Moleküls in einem eigens entworfenen Käfig diese Frage auf überraschende Weise beantwortet.
Studies of Anti‐HIV Transcription Inhibitor Quinolones: Identification of Potent N1‐Vinyl Derivatives
Authors: Tabarrini Oriana , Massari Serena , Daelemans Dirk , Meschini Francesco , Manfroni Giuseppe , Bottega Laura , Gatto Barbara , Palumbo Manlio , Pannecouque Christophe , Cecchetti Violetta 
Published: October 2010

AbstractThe 6‐desfluoroquinolones (6‐DFQs) are anti‐HIV agents that target Tat‐mediated transcription. This particular mechanism of action makes this class of compounds very attractive for further structural investigations. Identification of the pharmacophore required for inhibition will ultimately result in the design of more selective analogues for use in combination therapy for the treatment of HIV infections. We have focused on the pyridone ring of the quinolone nucleus present in these compounds, designing new modifications to broaden the structure–activity relationship knowledge base. Herein, we present novel and very potent anti‐HIV quinolones, most notably those bearing an amino or vinyl group at the N1 position. Attempts were made to determine the structural parameters necessary to impart potent anti‐HIV activity to the vinyl derivatives.
Defeating Radiation Damping and Magnetic Field Inhomogeneity with Spatially Encoded Noise
Authors: Michal Carl A. 
Published: October 2010

AbstractA simple NMR experiment capable of providing well resolved spectra under conditions where either radiation damping or static magnetic field inhomogeneity would broaden otherwise high‐resolution NMR spectra is introduced. The approach involves using a strong pulsed magnetic field gradient and a selective radio‐frequency pulse to encode a predetermined noise pattern into the spatial distribution of magnetization. Following readout in a much smaller field gradient, the noise sequence may be deconvolved from the acquired data and a high‐resolution spectrum is obtained, eliminating the effects of either radiation damping or the static field inhomogeneity. In the presence of field inhomogeneity a field map is also obtained from the same single transient. A quasi‐two‐dimensional version of the experiment eliminates the need for deconvolution and produces improved results with simplified processing, but without requiring a full two‐dimensional experiment. Example spectra are shown for both radiation damping and one‐dimensional field inhomogeneity with improvement in linewidths of more than a factor of 40.
Informed trading around merger and acquisition announcements: Evidence from the UK equity and options markets
Authors: Spyrou Spyros , Tsekrekos Andrianos , Siougle Georgia 
Published: October 2010

AbstractThis paper offers new evidence on informed trading around merger and acquisition announcements from the UK equity and options market. The analysis suggests that in about 25–33% of events there is abnormal option trading volume during the month that precedes the announcement. Such evidence is found in both call and put option volumes, is robust to different “estimation” and “event window” lengths, to different sub‐samples, and to liquidity considerations. These results support the argument that informed investors will transact in both the options and the stock market, and are comparable to results reported by the FSA in the cash market. © 2010 Wiley Periodicals, Inc. Jrl Fut Mark 31:703–726, 2011
Estradiol promotes spine growth and synapse formation without affecting pre‐established networks
Authors: Mendez Pablo , Garcia‐Segura Luis Miguel , Muller Dominique 
Published: October 2010

AbstractEstrogens regulate dendritic spine density, but the mechanism and significance of this effect for brain networks remain unknown. We used repetitive imaging over several days to investigate how 17β‐estradiol affected the turnover and long‐term behavior of dendritic spines in CA1 cells of hippocampal slice cultures. We find that 17β‐estradiol and serum in the culture medium tightly regulated spine density by promoting an increase in the rate of new spine formation and their transformation into synapses, without affecting spine elimination or stability. New spines formed during a transient 17β‐estradiol application were preferentially eliminated upon removal of the hormone, in contrast with pre‐existing spines that remained unaffected. Our results reveal that 17β‐estradiol transiently regulates the complexity of hippocampal circuits without causing major alterations of pre‐existing networks. © 2010 Wiley Periodicals, Inc.
Evaluating community participation as prevention: life narratives of youth
Authors: Janzen Rich , Mark Pancer S. , Nelson Geoffrey , Loomis Colleen , Hasford Julian 
Published: October 2010

AbstractCommunity‐based prevention programs strive to foster the composition of positive life stories, in part, by promoting active participation in community settings. This article used life narratives of youth to explore the experience of community participation and showed how such participation influenced their lives. Youth aged 18–19 years who participated in Better Beginning, Better Futures (n=62), a community‐based prevention program, when they were aged 4–8 years, recounted stories of their lives that showed significantly higher levels of participation in community programs and greater personal impacts of that involvement compared with youth who were not involved in Better Beginnings (n=34). Qualitative analysis of a subsample of these youth (n=34) revealed individual and community characteristics that were instrumental in fostering positive outcomes of community participation. The findings indicated both the utility of using a narrative approach to evaluate community‐based prevention programs and the value of community participation for children and youth. © 2010 Wiley Periodicals, Inc.
Cross‐sectional and longitudinal effects of sixth‐grade setting‐level norms for nonviolent problem solving on aggression and associated attitudes
Authors: Henry David , Chan Wing Yi 
Published: October 2010

AbstractSetting‐level norms are typically measured by using the mean of individual reports. Investigating norms for nonviolent problem solving, this study assessed the added value of two additional characteristics: the range of acceptable behaviors and the degree of consensus among individuals in each setting. Using data from 5,386 participants in a violence prevention project (74 classes), this study estimated the cross‐sectional and longitudinal effects of norm characteristics on aggression, beliefs about aggression, self‐efficacy for nonviolence, and beliefs about nonviolence. Each norm measure showed acceptable setting‐level reliability. Class mean approval predicted beliefs about aggression, self‐efficacy, and beliefs about nonviolence. With class means already in the model, the range of acceptable behaviors predicted additional cross‐sectional variance in all four outcomes. Consensus predicted aggression and beliefs about nonviolence beyond other characteristics. Mean approval and consensus had effects on growth in at least one outcome. Discussion focuses on the importance of setting‐level measurement and implications for intervention. © 2010 Wiley Periodicals, Inc.
Psychiatric morbidity and social capital in rural communities of the Greek North Aegean islands
Authors: Tseloni Andromachi , Zissi Anastasia , Skapinakis Petros 
Published: October 2010

AbstractWhich facets of social capital affect mental health in rural settings? This study explores the association between different aspects of social capital and psychiatric morbidity in rural communities of the Greek North Aegean islands. A large number of individual and community characteristics that may influence psychiatric morbidity are concurrently examined in multilevel models to account for the clustering of individuals within rural settings. The current findings indicate that psychiatric morbidity is, to a large extent, clustered within rural communities. Individuals' perceived divisions in the community, i.e., political party preference, landholdings, low social support networks, and lack of perceived solidarity, are associated with psychiatric morbidity according to theoretical expectation. At the community level, this risk is lower in villages with over 250 residents, where there are youth clubs or a common threat, for instance, property crime. © 2010 Wiley Periodicals, Inc.
TCT‐DMSO/[bmim]BF4: A novel promoter system for the synthesis of 3,5‐diaryl‐1,2,4‐thiadiazoles at ambient temperature
Authors: Khosropour Ahmad R. , Noei Jalil 
Published: October 2010

AbstractAn efficient and practical procedure for direct synthesis of 3,5‐diaryl‐1,2,4‐thiadiazoles by thioamides with 2,4,6‐trichloro‐1,3,5‐triazine (TCT) and dimethylsulfoxide using 1‐butyl‐3‐methylimidazolium tetrafluoroborate as an eco‐friendly reaction medium under ambient temperature is described. This protocol can be considered as a new procedure for 3,5‐diaryl‐1,2,4‐thiadiazoles synthesis. J. Heterocyclic Chem., (2010).
Synthesis and antibacterial evaluations of new pyridazino[4,3‐e][1,3,4]oxadiazines
Authors: Bakavoli Mehdi , Rahimizadeh Mohammad , Shiri Ali , Eshghi Hossein , Pordeli Parvaneh , Pordel Mehdi , Nikpour Mohsen 
Published: October 2010

AbstractSeveral derivatives of the new pyridazino[4,3‐e][1,3,4]oxadiazine ring system were prepared, and their antibacterial evaluations were performed on four different Gram‐negative and Gram‐positive bacteria. J. Heterocyclic Chem., (2010).
The Radziszewski oxidation of cycloalkylidene‐α‐(thiazol‐ 2‐yl)acetonitriles: A new approach toward spirooxiranes
Authors: Dotsenko Victor V. , Krivokolysko Sergey G. , Litvinov Victor P. 
Published: October 2010

AbstractUpon treatment with H2O2/KOH in EtOH or with Na2CO3/H2O2 in acetone, cycloalkylidene‐α‐(4‐arylthiazol‐2‐yl)acetonitriles afforded 2‐(4‐arylthiazol‐2‐yl)‐1‐oxaspiro[2.5]octane‐2‐carboxamides and 2‐(4‐arylthiazol‐2‐yl)‐1‐oxaspiro[2.4]heptane‐2‐carboxamides in excellent yields (76–100%). J. Heterocyclic Chem., 2011.
An enzyme‐mimetic chemical conversion and biogenetic outline for chemical marker pterocarponoid oxygen heterocycles from Kudzu vine
Authors: Khan Riaz A. 
Published: October 2010

AbstractAn enzymatic chemical conversion of isoflavone and chemical marker oxygen‐heterocycles pterocarponoids are carried out in an analogy to major subcellular enzymatic conversions involved in the natural biogenetic pathway and microbial interaction steps for oxygen‐proliferated products obtained from bioactive fractions of widely occurring Kudzu plant, Pueraria tuberosa. An outline for biogenesis of major pterocarponoid constituents from principal biogenetic precursor, deoxytuberosin, is also proposed for P tuberosa. J. Heterocyclic Chem., (2010).