bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Heterometallic Rare Earth‐Zinc Aryloxido Complexes and Their Application in Macrocyclic Lactones Polymerization
Authors: Kowaliński Adrian , Petrus Rafał , Chomiak Katarzyna , Lis Tadeusz 
Published: February 2025

ABSTRACTA series of heterometallic trinuclear aryloxides, [REZn2(sal‐Me)4Cl3(H2O)] (Hsal‐Me = methyl salicylate; REIII = YIII (3), HoIII (4), ErIII (5)), or hexanuclear aryloxides, [RE2Zn4(μ3‐OH)2(μ‐OMe)2(sal‐Me)6Cl4] (REIII = YIII (6), HoIII (7), ErIII (8)) were synthesized via the reaction of zinc precursors [Zn4(sal‐Me)8] (1) or [Zn4(μ3‐OMe)2(sal‐Me)6] (2) with 2 equiv of rare earth chlorides (RECl3). The catalytic activity of complexes 1–8 was evaluated in the ring‐opening polymerization (ROP) of pentadecanolide (PDL) and hexadecanolide (HDL) to assess the effect of the initiator structure on the polymerization process and the physicochemical properties of the resulting polyesters. The obtained low molecular weight polypentadecanolides (PPDLs) and polyhexadecanolides (PHDLs) were investigated as modifying agents for commercial polylactide (PLLA) resin and used to prepare PLLA/PPDL or PLLA/PHDL blends.Blending PLLA with PPDL or PHDL broadens its cold crystallization exotherm, shifts the Tcc to higher temperatures, and hinders the growth of PLLA crystals, ultimately leading to reduced thermostability and faster degradation.
Construction of Type II Bi‐TCPP/Bi2S3 Heterojunction With Oxygen‐Rich Vacancy for Enhanced Photocatalytic Activity
Authors: Yuan Zehua , Tuerhong Munire , Aisikaer Xirenayi , Mamtmin Gulgina 
Published: February 2025

ABSTRACTThe Type II heterojunction, characterized by its favorable band alignment, facilitated efficient charge separation in photocatalysts. Concurrently, oxygen vacancies can enhance light absorption and activated reactants, thereby improving photocatalytic efficiency. This study presented the synthesis of Bi‐TCPP/Bi2S3 heterojunction photocatalysts, which were rich in oxygen vacancies, using a green, one‐pot method. The composite exhibited superior photoelectrochemical and photocatalytic reduction properties, achieving a rate constant of 0.03829 min−1 for Cr(VI) reduction and a remarkable reduction rate of 95.73%. After five cycles, the photocatalytic activity remained above 91.30%, demonstrating excellent stability and efficiency in reducing persistent pollutants. This work introduced a novel strategy for photocatalyst design and made a significant contribution to the fields of environmental remediation and green chemistry.
Effects of Incorporation of Organic Montmorillonite on Improving the Wear Resistance of Nylon 66/Glass Fiber Based Composites and the Mechanisms
Authors: Jiang Feng , Shi Yanqin , Zhang Xutao , Chen Si , Zhou Lihui , Lu Longwei , Lu Jinqiang , Che Shijun , Wang Xu 
Published: February 2025

ABSTRACTDifferent content of organic montmorillonite was added into Nylon 66/glass fiber composites to improve the wear resistance of the composites. It found that the wear loss and wear rate of the nylon 66/glass fiber composites with 0.5 wt% organic montmorillonite were only 8.83 mg and 0.52%, reduced by 25.4% and 29.3% compared with the nylon 66/glass fiber composite without organic montmorillonite. Moreover, the friction curves of nylon 66/glass fiber/organic montmorillonite composites with a small coefficient of friction entered the stable friction stage quickly. Especially, the glass fiber in nylon 66/glass fiber/organic montmorillonite composites was arranged more regularly and was worn less as shown in the images of SEM. The wear resistance mechanisms of the nylon 66/glass fiber/organic montmorillonite composites were regarded as that organic montmorillonite with self‐lubricating effect oriented in the nylon 66/glass fiber composites and enhanced the crystallinity of the nylon 66 matrix. Moreover, organic montmorillonite aggregated on the surface of glass fiber due to the hydrogen bonds between organic montmorillonite and glass fiber, resulting in the orientation of glass fiber, the increase of the flowability of the composites, and the decrease of the “floating fiber” problems. Thus, this work revealed that when there were glass fiber and organic montmorillonite in nylon 66, the interaction between glass fiber and organic montmorillonite had an obvious effect on the wear resistance of the composites.
Electrical Manipulation of Intervalley Trions in Twisted MoSe2 Homobilayers at Room Temperature
Authors: Rosa Bárbara L. T. , Junior Paulo E. Faria , Cadore Alisson R. , Yang Yuhui , Koulas‐Simos Aris , Palekar Chirag C. , Tongay Seth Ariel , Fabian Jaroslav , Reitzenstein Stephan 
Published: February 2025

AbstractThe impressive physics and applications of intra‐ and interlayer excitons in a transition metal dichalcogenide twisted‐bilayer make these systems compelling platforms for exploring the manipulation of their optoelectronic properties through electrical fields. This work studies the electrical control of excitonic complexes in twisted MoSe2 homobilayer devices at room temperature. Gate‐dependent micro‐photoluminescence spectroscopy reveals an energy tunability of several meVs originating from the emission of excitonic complexes. Furthermore, this study investigates the twist‐angle dependence of valley properties by fabricating devices with stacking angles of θ ∼ 1°, θ ∼ 4° and θ ∼ 18°. Strengthened by density functional theory calculations, the results suggest that, depending on the twist angle, the conduction band minima and hybridized states at the Q‐point promote the formation of intervalley hybrid trions involving the Q‐and K‐points in the conduction band and the K‐point in the valence band. By revealing the gate control of exciton species in twisted homobilayers, these findings open new avenues for engineering multifunctional optoelectronic devices based on ultrathin semiconducting systems.
A Bright Red Molecular Marker for Super‐Resolution Imaging of DNA Nanoscale Organization in Cells
Authors: Chandra Mondal Iswar , Anjum Farhan , Salam Abdul , Deka Snata , Mandal Sayan , Karmakar Anirban , Kanti Nandi Chayan , Ghosh Subrata 
Published: February 2025

AbstractSEZ‐NDEA, a long‐range emissive molecular marker, can be used in fluorescence microscopy for super‐resolution imaging (SRRF) of DNA nanoscale organization in cells. The developed probe stains the cell nucleus with minimum cytoplasmic leakage with good contrast. It showed good photostability in cellular medium.
Diverse Fluorescent Probe Concepts for Detection and Monitoring of Reactive Oxygen Species
Authors: Chaturvedi Vineeta , Kumari Ritu , Sharma Prakriti , Pati Avik K. 
Published: February 2025

AbstractWorld‐wide research on reactive oxygen species (ROS) continues to reveal new information about the role and impact of ROS on human health and disease. ROS are generated in live cells as a byproduct of aerobic metabolism. Physiological concentrations of cellular ROS are important for signaling and homeostasis, but excessive generation of ROS causes apoptotic and necrotic cell death and various health disorders. Fluorescence technology is a powerful tool to detect, monitor, and image cellular ROS. The present review provides an overview of diverse organic dye‐based fluorescent probe concepts that involve modifications of traditional fluorescent dyes utilizing basic principles of dye chemistry and photophysics. Fluorescence responses of the probes and their specificity towards ROS are discussed through analyses of their photophysical and photochemical parameters. We also provide an outlook on future directions of ROS‐responsive fluorescent dyes, which could enable the design and development of advanced probes for gaining deeper insights into redox biology.
Self‐assembled Supra‐Plate from Gold Nanoparticle with Zn(II) and 1H‐pyrazole‐3,5‐dicarboxylic Acid for Antibacterial Studies
Authors: Sahu Jitendra K. , Adhikary Rajsekhar , Dalal Sancharika , Hazra Saugata , Sadhu Kalyan K. 
Published: February 2025

AbstractInteractions of aromatic nitrogen and carboxylate group of 1H‐pyrazole‐3,5‐dicarboxylic acid (PDC) with bivalent Zn(II) metal ions and gold nanoparticle (AuNP, average diameter ~16 nm) surface has been targeted in this current study. The time‐dependent absorption and structural analysis experimentally demonstrate the combined role of PDC and metal ion towards the self‐assembly of AuNP. The collective interaction in solution triggers self‐assembly, which results in the synthesis of unique Au/Zn@PDC supra‐plates at room temperature. The Zn(II) induced supra‐plates have been further characterized by X‐ray diffraction (XRD) and X‐ray photoelectron spectroscopy (XPS). The selectivity of the self‐assembly for supra‐plate architectures has been verified with handful of other metal ions such as Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Mg(II) and Pb(II). Among these studied metal ions, Pb(II) only provides the self‐assembled supra‐sphere formation under identical conditions. Pb(II) being a toxic metal ion, antibacterial properties have been explored for Au/Zn@PDC supra‐plates with four significant human pathogens: Methicillin‐resistant Staphylococcus aureus (MRSA) ATCC BAA‐44, Methicillin‐sensitive Staphylococcus aureus (MSSA) S18 (clinical isolate), Klebsiella pneumoniae ATCC BAA‐1706, and Klebsiella pneumoniae MDR 36 (clinical isolate). Compared to the parent constituents, these bacterial cells experience greater damage to the cell wall, when treated with Au/Zn@PDC supra‐plates with a minimum inhibitory concentration (MIC) of 0.2‐0.8 ng/mL.
Bayesian Forecasting of Value‐at‐Risk and Expected Shortfall in Cryptocurrency Markets: A Nonlinear Semi‐Parametric Framework
Authors: Chen Cathy W. S. , Chen Po‐Hui , Hsu Ying‐Lin 
Published: February 2025

ABSTRACTCryptocurrencies exhibit high volatility, emphasizing the importance of accurately measuring tail risk in their markets. This research incorporates a threshold‐switching mechanism into Taylor's ES‐CAViaR models that unveil features such as asymmetry and jump phenomena. These enhancements effectively capture the diverse tail risks of cryptocurrencies while enabling the simultaneous forecasting of both Value‐at‐Risk (VaR) and Expected Shortfall (ES). The proposed models incorporate two types of functions to address the VaR and ES nexus with the option to use the rolling standard deviation of returns as a short‐term volatility proxy as a regressor. We estimate the parameters and forecast tail risk within a Bayesian framework. Taking the two largest cryptocurrencies by market capitalization, Bitcoin and Ethereum, we assess the one‐step‐ahead forecasting performance over a four‐year out‐of‐sample period using a rolling window approach. The comparative results from backtests and five scoring functions among eight competing models support the conclusion that models with a threshold mechanism capture the tail risk of cryptocurrencies more accurately than other risk models.
Einfluss des Trainingszeitraums auf die Anomalieerkennung in Monitoringdaten von Brücken
Authors: Wedel Frederik , Marx Steffen 
Published: February 2025

AbstractDer Erhalt von Brückenbauwerken bei gleichzeitiger Gewährleistung der Sicherheit erhöht die Relevanz automatisierter Monitoringsysteme. Die Regression Based Thermal Response Prediction Method (RBTRPM) aus dem Bereich des maschinellen Lernens ist eine vielversprechender Ansatz zur automatisierten Erkennung struktureller Änderungen. Die auf Grundlage von Temperaturmessungen vorhergesagten Tragwerksreaktionen mithilfe von Machine‐Learning‐Modellen werden dem gemessenen Tragverhalten gegenübergestellt und die Abweichungen erkannt und bewertet. Obwohl die RBTRPM bereits 2014 eingeführt wurde, war die praktische Anwendung bisher begrenzt. In dem Beitrag wird die Anwendung der RBTRPM am Beispiel der Eisenbahnüberführung (EÜ) Itztalbrücke in der Praxis analysiert. Fokus der Untersuchungen sind der Zeitpunkt des Trainings der ML‐Modelle sowie die Länge des Trainingszeitraums. Beide Parameter haben einen signifikanten Einfluss auf die Vorhersagegenauigkeit. Ziel ist es, die Methode möglichst schnell in die Anwendung zu bringen, um strukturelle Anomalien frühzeitig zu erkennen. Bei einem kleinen Zeitraum können die Modelle jedoch u. U. keine hohe Genauigkeit erzielen. Diese Gratwanderung wird untersucht und entsprechende Empfehlungen werden aufgezeigt. Zudem wird festgestellt, dass das Extrapolieren mithilfe solcher Modelle zu ungewünschten Effekten führt. Die Untersuchungen bestätigen die Wirksamkeit der RBTRPM auch in der Praxis, sie erfordert jedoch eine sorgfältige Auswahl der Trainingsparameter.
Investigating the impact of Ras‐related protein RAB7A on colon adenocarcinoma behavior and its clinical significance
Authors: Shan Zhili , Chen Xin , Chen Hong , Zhou Xiaojun 
Published: February 2025

AbstractThe Ras‐related protein RAB7A has been implicated in the development and prognosis of various cancers. This study aims to investigate the prognostic significance of RAB7A in colon adenocarcinoma (COAD). We conducted a retrospective cohort study of COAD cases to assess RAB7A expression and its clinical relevance. The chi‐square test was employed to establish associations between clinical features and RAB7A expression. Survival analyses, including Kaplan–Meier and Cox regression, were employed to evaluate the impact of RAB7A expression and clinical characteristics on COAD patient outcomes. Furthermore, we validated our clinical findings using The Cancer Genome Atlas (TCGA) dataset. To elucidate the tumor‐related role of RAB7A in COAD, we conducted cellular assays and mouse models. Elevated RAB7A expression in COAD tissues exhibited significant associations with tumor size, invasion depth, and lymph node metastasis (all p < 0.05). Univariate and multivariate analyses revealed that high RAB7A expression was significantly correlated with poorer overall survival. In vitro cellular assays, coupled with knockdown strategies, demonstrated that RAB7A promotes COAD tumor proliferation and invasion, a finding further substantiated by in vivo xenograft experiments. RAB7A may serve as a valuable biomarker and potential therapeutic target in the management of COAD.
Conceptual Approach for Aerobic Autotrophic Gas Cultivation in Shake Flasks: Overcoming the Inhibitory Effects of Oxygen in Cupriavidus necator
Authors: Di Bisceglie Federico , García Navarro Javier , Lombard Eric , Kratzer Regina , Kourist Robert , Guillouet Stéphane E. 
Published: February 2025

ABSTRACTThis study conceptualizes the design of a small‐scale system (250 mL–1 L) for the autotrophic cultivation of hydrogen‐oxidizing bacteria, such as the representative strain Cupriavidus necator. The research aimed to systematically investigate the impact of bottle volume and gas composition, particularly oxygen concentration, on the growth and performance of C. necator during autotrophic cultivations. To this end, customized, pressure‐tight, baffled glass bottles of various sizes (250, 500, and 1000 mL) and gas mixtures with varying oxygen concentrations (4%, 8%, and 12% v/v) were tested. Growth was monitored by measuring optical density. The maximum specific growth rate (µmax), the biomass production rate (BPR), the volumetric gas–liquid mass transfer coefficient (kLa), and the oxygen transfer rate were calculated. Among the various combinations, the 1000‐mL bottles demonstrated the highest µmax (0.13 h−1) and the second‐highest BPR (0.074 g L−1 h−1) at an oxygen concentration of 8%, without the need to refill the headspace. The proposed small‐scale system offers a swift and replicable method for concurrently investigating multiple autotrophic cultivations. In this regard, increasing the size of the bottle flask proved to be an efficient strategy to minimize the periodicity for gas refilling. Due to the inhibitory effect of oxygen, changing the liquid–gas volume ratio in hydrogen‐driven shake flask cultivation had so far strongly influenced the growth rate. Our results provide a solid foundation for the scaling and optimization of small‐scale cultivation of chemolithotrophic bacteria and will facilitate future parallelization and, hence, optimization of metabolic aspects.
Population‐Based Norms for the Montreal Cognitive Assessment in Arab Adults
Authors: Amro Iman , Hamadi Aisha M. Al , Salem Alaa A. El , Chivese Tawanda , Wilkins Stacy S. , Khaled Salma M. 
Published: February 2025

ABSTRACTObjectiveThe Montreal Cognitive Assessment (MoCA) is a brief screening instrument for detecting mild cognitive dysfunction, a precursor to many cognitive disorders, such as dementia, which have increased in prevalence globally. Qatar, a small high‐income country, has the largest projected increase in dementia of any country in the Middle East. Yet no population‐based norms for cognitive function are available to date.MethodsAs part of the first national cross‐sectional study of mental health, a total of 395 Qatari and non‐Qatari Arabs, 18–74 years of age, were evaluated face‐to‐face using the Arabic version of the original MoCA (version 7.1). We computed raw and demographically (gender, age in years, and four education categories) adjusted scores for the overall MoCA test and six domains (visuospatial, executive function, attention, language, delayed memory, and orientation). The percentile ranking of raw and adjusted normative (z) scores was computed. The 5th percentile ranking was used to derive potential cut‐offs for the overall test and the six related domains.ResultsFemale gender, older age, and lower levels of education were associated with poorer overall test scores. The following MoCA overall test and domains cut‐off scores (rounded to the nearest integer) were identified: MoCA (22), visuospatial (2), executive (2.5), attention (4), language (4), and delayed memory (3).ConclusionsOn the basis of our population‐based data, scores below these 5th percentile cut‐offs may warrant further testing and clinical follow‐up for mild cognitive impairment (MCI) in otherwise healthy Arab adults.
The Mediating Role of Financial Reporting Quality in the Relationship Between CEO Power and Carbon Emission Disclosures: Evidence From Vietnamese Companies
Authors: Khuong Nguyen Vinh , Tai Vu Tran Trong , Anh Le Huu Tuan 
Published: February 2025

ABSTRACTThis study investigates the impact of chief executive officer (CEO) power on carbon emission disclosures (CDI) and the mediating role of financial reporting quality (FRQ) in this relationship. We employ the two‐step system generalized method of moments (Sys‐GMM) estimator to examine the relationship between CEO power and CDI and the mediating role of FRQ. We utilize a dataset of Vietnamese listed firms between 2015 and 2022, totalling 494 firm‐year observations. We further perform a battery of robustness tests. We find that CEO power positively influences CDI, indicating that CEOs may enhance transparency to bolster their reputation. However, our results also reveal a negative impact of CEO power on FRQ, supporting the notion that powerful CEOs might prioritize personal interests at the expense of reporting integrity. Additionally, we demonstrate that FRQ mediates the relationship between CEO power and CDI, suggesting that while CEOs promote environmental disclosure' transparency, they may concurrently engage in earnings management practices that diminish FRQ. This research contributes to the literature by providing empirical evidence on the role of CEO power in facilitating both financial and environmental disclosures in an emerging market context. The study highlights the mediating role of FRQ, offering new insights into the governance mechanisms that influence corporate transparency.
Novel Multifunctional Aldose Reductase Inhibitors Based on Quinoxalin‐2(1H)‐one Scaffold for Treatment of Diabetic Complications: Design, Synthesis, and Biological Evaluation
Authors: Hao Xin , Wang Xuying , Jiang Qianxi , Zhu Yannan , Zhu Yuqing , Chen Mengmeng , Qi Gang , Zhu Changjin , Han Zhongfei 
Published: February 2025

ABSTRACTDiabetic complications, such as nephropathy, cataracts, and retinopathy, are the main threat and primary reason for death in diabetic patients. Numerous pieces of evidence demonstrated aldose reductase (ALR2) and oxidative stress are the two most important intervention targets for the treatment of diabetic complications. We designed a new type of multifunctional ALR2 inhibitor (ARI) based on the quinoxalin‐2(1H)‐one scaffold, which combined the inhibition of aldose reductase and direct antioxidation into an organic whole. Most of the compounds 6 showed potent ALR2 inhibition with IC50 values ranging from 0.091 to 10.214 µM, and 2‐(4‐(4‐bromo‐2‐fluorobenzyl)‐2‐oxo‐3,4‐dihydroquinoxalin‐1(2H)‐yl)acetic acid (6g) was the most active. All compounds were slightly active with an aldehyde reductase inhibition percentage of no more than 40.7%, demonstrating good selectivity for ALR2. Further introduction of a phenolic hydroxyl group to obtain compounds (6j–l), (6l) containing phenolic 3,5‐dihydroxyl showed the best antioxidant activity with 2,2‐diphenyl‐1‐picrylhydrazyl radical scavenging 94.62%, 90.21%, and 82.75% at the concentration of 100, 50, and 10 µM, respectively, even as strong as the well‐known antioxidant Trolox. Molecular docking was also consistent with the biological data and explained the ALR2 inhibition and selectivity reasonably. Therefore, these results suggested success in the construction of multifunctional ARIs having potency for ALR2 inhibition and antioxidation.
Onosma rutila (Boraginaceae) Plant Extract: Chemical Composition, Biological Analysis, and Film Forming Potential With Polymers
Authors: Binzet Riza , Binzet Gun , Turunc Ersan , Cevik Pınar Küce , Demir Didem , Arslan Hakan 
Published: February 2025

ABSTRACTThis study aimed to integrate the ethanolic extract obtained from the aerial parts of endemic Onosma rutila as a new bioactive ingredient into polymeric films and to produce biofunctional composite thin films for use in biomedical applications. Initially, the definition of the plant extract was carried out in terms of chemical composition and biological activities. The main component of the extract was revealed as 9,12‐octadecadienoic acid (15.90%). Antimicrobial activity was evaluated against a total of five microorganisms by the well diffusion method and microdilution technique. MIC99 results showed the lowest inhibition against Candida albicans, suggesting a stronger antifungal effect than antibacterial activity. Also, the 2,2‐diphenyl‐1‐picrylhydrazyl scavenging activity of O. rutila, ascorbic acid, and butylated hydroxytoluene at 500 µg/mL showed values ​​of 87.63, 90.13, and 46.82%, respectively. In the next phase, the extract, which was revealed to be an effective biological agent, was incorporated into the polymer solutions prepared based on chitosan and polyvinyl alcohol at different ratios to produce a series of thin films. For application purposes, the thin films' chemical compositions, water retention capacities, and morphological properties were determined and their potential for use as wound dressing material was evaluated.