bluuebunny/crossref_metadata_2025_split huggingface dataset:
A construction approach to innovative verbs in Japanese
Authors: Tsujimura Natsuko , Davis Stuart 
Published: October 2011

Abstract
Innovative verbs in Japanese are formed from nouns of various sources including loanwords, Sino-Japanese nouns, mimetics, and proper names. Regardless of their different origin, these innovative denominal verbs exhibit a collection of intriguing properties, ranging from phonological, morphological, to semantic and pragmatic. These properties are not strictly predictable from the component parts including the nature of the parent noun and verbal morphology. Such an unpredictable nature is suggestive of a constructional analysis. The form-meaning-function complex takes a templatic representation, which expresses the phonological and morphological characteristics, and associated with it are semantic and pragmatic properties. These phonological, morphological, semantic, and pragmatic properties combine to capture the nature of innovative denominal verbs as a construction. The analysis supports the idea of applying construction grammar to morphology along the lines of the developing field of construction morphology (e.g., Booij, Compounding and derivation: Evidence for construction morphology, John Benjamins, 2005, Construction morphology and the lexicon: 34–44, Cascadilla Press, 2007, Linguistische Berichte 19: 1–14, 2009a, Compounding and construction morphology, Oxford University Press, 2009b). We further show how insights from templatic (or prosodic) morphology (e.g., McCarthy and Prince, Prosodic morphology, University of Massachusetts and Brandeis University, 1986, Natural Language and Linguistic Theory 8: 209–282, 1990) can be conceptualized in terms of construction grammar.
Dissolved organic matter concentration changes in river waters of Latvia
Authors: Kļaviņš Māris , Kokorīte Ilga , Rodinovs Valērijs 
Published: October 2011

Dissolved organic matter concentration changes in river waters of Latvia
Amounts of natural organic matter in surface waters reflect the character and intensity of biological processes in water bodies, human impact and depend on the physico-geographical environment and land-use in the catchments. Thus, analysis of the concentrations and loadings of organic substances to adjacent water bodies can be used to indicate environmental change and human impacts. This study revealed significant increasing trends of total organic carbon (TOC) and water colour in most of the studied Latvian rivers during the last decade. However, over longer time periods, there have been pronounced oscillations of TOC concentrations, stressing the importance of long-term changes of river discharge. On a yearly basis, there was a positive correlation between parameters of organic matter concentration and discharge in all selected rivers. The impact of discharge on concentrations of organic matter can be masked by other factors, such as changes in precipitation, biological processes, soil types and land-use.
Earthworm (Oligochaeta, Lumbricidae) communities in common soil types under intensive agricultural practice in Latvia
Authors: Ventiņš Jānis 
Published: October 2011

Earthworm (Oligochaeta, Lumbricidae) communities in common soil types under intensive agricultural practice in Latvia
Studies of earthworm populations in the framework of the State Agricultural Land Monitoring Programme were performed during 1992-1998 at six sites representing the common soil types of Latvia. The earthworm communities were examined as indicators of soil conditions in relation to soil type, terrain, agricultural practice and meteorological factors. In total six earthworm species were found. Only two species, Aporrectodea caliginosa and Lumbricus rubellus, were present in all plots. The highest density of earthworms was observed in loamy soils on lower terrains. The lowest density was observed on sandy soils on high terrain position. In plots with intensive agricultural practice, Aporrectodea caliginosa showed the highest relative abundance reaching close to 100%, but in pastures this species was accompanied with 2-3 subdominant species. The main factors affecting earthworm density were meteorological conditions. In permanent pasture the seasonal variability of earthworm number was lower than in plots with intensive soil tillage, where earthworm density was lower. Under favourable meteorological conditions in loamy soils, a negative impact of soil management was not observed, whereas in sandy loam soils intensive tillage had a much more negative effect on worms. In pasture soils earthworms reached high density even in sandy soils.
Cold shores in warming times - current state and future challenges in High Arctic coastal geomorphological studies
Authors: Strzelecki Mateusz 
Published: October 2011

Cold shores in warming times - current state and future challenges in High Arctic coastal geomorphological studies
Many of the existing intellectual paradigms regarding the functioning of the polar coastal zone are now out-dated, based on descriptive geomorphology and a limited process-based understanding. Currently, among many components of Arctic landscape adjusting to global warming, the coastal zone is probably the most critical one both in terms of rapidity of environmental change as well as importance for human communities living in circumpolar regions. This issue was often raised during the 4th International Polar Year 2007-2008 and encouraged the scientific community to focus on the state of cold region coasts in more detail. In this paper I summarize the most recent developments in Arctic coastal geomorphology with a particular focus on the Svalbard Archipelago and draw attention to the research challenges awaiting further investigation. This paper highlights the need for a greater understanding of the controls on High Arctic coastal geoecosystems, especially given the potential for accelerated warming and sea-level rise in the coming decades and centuries. Many of presented views benefited from discussions with Professor Andrzej Kostrzewski - to whom this volume is dedicated.
Regional differences in the influence of the North Atlantic Oscillation on seasonal river runoff in Poland
Authors: Wrzesiński Dariusz 
Published: October 2011

Regional differences in the influence of the North Atlantic Oscillation on seasonal river runoff in Poland
In this paper, an analysis of monthly and seasonal runoff volumes in two stages of the North Atlantic Oscillation are presented. The analysis embraced runoff at 146 profiles located on 96 Polish rivers during the years 1951-2000. The changes in the runoff conditions of Polish rivers in the two NAO stages and their spatial diversity were determined based on the differences between runoff observed in the years of exceptionally high (NAODJFM > 2,0) and low (NAODJFM < -2,0) values of the winter NAO index. The results of the research indicate that the influence of the North Atlantic Oscillation on the runoff of Polish rivers is diverse in terms of time and space. A classification of rivers was made in terms of the similarity of deviations of their seasonal runoff between the different NAODJFM stages. In the classification procedure use was made of Ward's method of hierarchical grouping. In this way, five classes of the river profiles under analysis were obtained. Environmental conditions in the catchments and hydrological regime features clearly influence the regional differences in the impact of the North Atlantic Oscillation on the flow of rivers.
Chelidurella guentheri Galvagni, 1994 (Dermaptera: Forficulidae) - an overlooked earwig species in Poland
Authors: Jaskuła Radomir , Soszyńska-Maj Agnieszka , Hikisz Jacek 
Published: October 2011

Chelidurella guentheri Galvagni, 1994 (Dermaptera: Forficulidae) - an overlooked earwig species in Poland
Chelidurella guentheri Galvagni, 1994 (Dermaptera) is reported from Poland for the first time. As a result the Polish checklist contains seven dermapteran species.
Contribution to the knowledge of Yponomeutoidea (Lepidoptera). III. Argyresthia (Blastotere) uralensis sp. n., a new species from Russia (Lepidoptera: Argyresthiidae)
Authors: Baraniak Edward , Junnilainen Jari 
Published: October 2011

Contribution to the knowledge of Yponomeutoidea (Lepidoptera). III. Argyresthia (Blastotere) uralensis sp. n., a new species from Russia (Lepidoptera: Argyresthiidae)
Argyresthia (Blastotere) uralensis sp. n. is described from Russia. Type specimens were obtained at the end of June in virgin taiga forests in the southern Ural Mountains. A. (B.) uralensis belongs to the same species group as A. (B.) glabratella Zeller, 1847 having characteristic cornuti in the aedeagus in the male (Friese 1969).
Proximal Femur Fracture in a Patient Referred to a Physical Therapist for Knee Pain
Authors: Sandoval Roberto 
Published: October 2011

The patient was a 33-year-old man who presented to the emergency department with complaints of left knee pain. The patient's knee pain was located medially and described as a constant deep ache that worsened with weight bearing. Radiographs did not demonstrate any evidence of fracture, subluxation, or dislocation, and subsequently, the patient was referred by his primary care physician to a physical therapist. Examination of his left hip revealed markedly decreased range of motion, with reproduction of the patient's left knee pain. Radiographs of the left hip were ordered, which revealed a comminuted, impacted fracture of the proximal femur. J Orthop Sports Phys Ther 2011;41(10):795. doi:10.2519/jospt.2011.0420
Effect of agriculture and presence of American beaver Castor canadensis on winter biodiversity of mammals
Authors: Nelner Tim B. , Hood Glynnis A. 
Published: October 2011

AbstractSeveral metrics of biodiversity are used to assess the variability and abundance of multiple species across various ecological levels. Previous research suggests that biodiversity in agricultural areas is diminished due to habitat fragmentation and alterations to natural vegetation. Contrary to the effects of agriculture, the American beaver Castor canadensis has been shown to have a significant contribution to increased biodiversity. Our study focuses on the biodiversity of mammals in wetland areas of the southern mixed‐wood boreal forest natural region of east‐central Alberta, Canada. We compared various measures of biodiversity levels of mammals in the winter months between wetlands on agricultural land and wetlands in Miquelon Lake Provincial Park (MLPP). Similarly, we compared wetlands with active and inactive beaver colonies to determine differences in winter biodiversity of mammals and the amount of water coverage within a pond. We collected data using winter tracking surveys and analyzed the data using geographic information systems (GIS) techniques. We found that winter biodiversity of mammals was higher at the sites within the protected area (MLPP) than at those on agricultural lands. However, our data also suggest that forested areas surrounding agricultural wetlands may play an important role in maintaining biodiversity within agricultural areas. The presence of beavers alone was not a significant factor in relation to winter biodiversity, but the presence of the species was important for maintaining water levels of agricultural wetlands, which in turn plays a role in resource heterogeneity.
The strong and the hungry: bias in capture methods for mountain hares Lepus timidus
Authors: Bisi Francesco , Newey Scott , Nodari Mosè , Wauters Lucas A. , Harrison Annabel , Thirgood Simon , Martinoli Adriano 
Published: October 2011

AbstractEstimating density, age and sex structure of wild populations is a key objective in wildlife management. Live trapping is frequently used to collect data on populations of small and medium‐sized mammals. Ideally, sampling mammal populations by live capturing of individuals provides a random and representative sample of the target population. Trapping data may, however, be biased. We used live‐capture data from mountain hares Lepus timidus in Scotland to assess sampling bias between two different capture methods. We captured hares using baited cage traps and long nets on five study areas in the Scottish Highlands. After controlling for the effects of body size, individuals caught in traps were lighter than individuals caught using long nets, suggesting that the body condition of hares differed between the capture methods. This tendency may reflect an increased risk‐taking of individuals in poorer body condition and less aversion to entering traps in order to benefit from eating bait. Overall, we caught more adult hares than juveniles and more female hares than males. Our results show that estimates of density and population structure of mountain hares using live‐capture data could be affected by the capture method used. We suggest that live‐capture studies employ more than one capture method and test for heterogeneity in capture probability to minimise potential bias and achieve reliable estimates of population parameters.
68Ga-NODAGA-RGDyK for αvβ3 integrin PET imaging
Authors: Viertl D. , Baechler S. , Dunet V. , Kosinski M. , Poitry-Yamate C. , Rüegg C. , Prior J. O. , Buchegger F. 
Published: October 2011

SummaryAim: To visualize neovasculature and/or tumour integrin αvβ3 we selected the binding moiety Arg-Gly-Asp-D-Tyr-Lys (RGDyK) coupled to NODAGA for labeling with 68Ga. Methods: NODAGA-RGDyK (ABX) was labeled with the 68Ga eluate from the 68Ge generator IGG100 using the processor unit PharmTracer. Biodistribution was measured in female Hsd mice sacrificed 10, 30, 60 and 90 min after i. v. injection of 68Ga-NODAGA-RGDyK for OLINDA dosimetry extrapolated to humans. Tumour targeting was studied in SCID mice bearing A431 and other tumour transplants using microPET and biodistribution measurements. Results: Effective half-life of 68Ga-NODAGA-RGDyK was ∼25 min for total body and most organs except liver and spleen that showed stable activity retention. With a bladder voiding interval of 0.5 h the calculated effective dose (ED) was 0.012 and 0.016 mSv/MBq for males and females, respectively. Rapid uptake within 10 min was observed in A431 tumours with dynamic PET followed by a slow release. Biodistribution measurements showed a 68Ga-NODAGARGDyK uptake in A431 tumours of 3.4 ± 0.4 and 2.7 ±0.3%ID/g at 1 and 2 h, respectively. Similar uptakes were observed in a mouse and human breast and ovarian cancer xenografts. Co-injection of excess (5 mg/kg) unlabeled NODAGA- RGDyK with the radiotracer reduced tumour uptake at one hour to 0.23 ± 0.01%ID/g, but similarly decreased uptake in normal organs as well. When unlabeled peptide was injected 15 min after 68Ga- NODAGA- RGDyK, uptake diminished particularly in tumour and adrenals, suggestive of a different binding mode compared with other normal tissues. Conclusion: NODAGA- RGDyK was reliably labeled with 68Ga and revealed a predicted ED of 0.014 mSv/MBq. Tumour uptake was rapid and significant and was chased with unlabeled RGDyK in a similar manner as adrenal uptake.
Selenium‐ and Tellurium‐Containing Organic π‐Conjugated Oligomers and Polymers
Authors: Patra Asit , Bendikov Michael 
Published: October 2011

AbstractOrganic electronic materials are one of the fastest developing fields of chemistry because of both inherent interest in the synthesis and properties of advanced materials and their many practical applications. While almost all organic electronic materials consist of carbon based πconjugated backbones, a majority of these skeletons also include some heteroatoms. Thiophene based oligomers and polymers are among the most studied organic electronic materials. Yet, despite their potential advantages, selenium‐containing oligomers and polymers have attracted surprisingly scant attention compared to the huge interest in thiophene based materials in recent decades. Few tellurium‐containing oligomers and polymers have been prepared, mostly because of a lack of synthetic methodologies for their preparation and their relatively poor stability.This chapter discusses πconjugated oligomers and polymers that contain selenium or tellurium atoms in the backbone. Most of these oligomers and polymers are selenophene based materials with only a few examples of tellurophene based oligomers and polymers known. Examples of selenium‐ and tellurium‐containing organic polymeric and oligomeric materials that have selenium or tellurium atoms in the backbone but not as a part of the heterocyclic ring are quite rare and will be discussed toward the end of this chapter. Particular attention is focused on approaches for synthesizing these selenium‐ and tellurium‐containing oligomers and polymers, on their special properties, and on highlighting their performance as organic electronic materials.
Synthesis and Histamine H3 and H4 Receptor Activity of Conformationally Restricted Cyanoguanidines Related to UR‐PI376
Authors: Geyer Roland , Buschauer Armin 
Published: October 2011

AbstractRecently, we identified highly potent agonists of the human histamine H4 receptor (hH4R) among a series of imidazolylbutylcyanoguanidines. Aiming at improved selectivity for the hH4R relative to the H3 receptor (hH3R), the flexible tetramethylene linker connecting imidazole ring and cyanoguanidine group was replaced by conformationally restricted carbocycles. Introduction of a para‐ or a meta‐phenylene spacer yielded only very weakly active compounds at both hH3R and hH4R (investigated in [35S]GTPγS binding assays using Sf9 insect cell membranes expressing hHxR subtypes). By contrast, the incorporation of a more flexible cyclohexane‐1,4‐diyl linker resulted in EC50 or KB values ≥110 nM at hH4R and hH3R. Quality of action, potency and receptor subtype selectivity of the investigated compounds depend on the stereochemistry: Cis‐configured diastereomers prefer the hH4R and are partial agonists, whereas trans‐isomers are antagonists at the hH4R. At the hH3R the trans‐diastereomers are superior to the cis‐isomers by a factor of 10. The results on imidazolylcycloalkylcyanoguanidines suggest that variation of ring size and optimization of the stereochemistry may be useful to increase the potency and selectivity of hH4R agonists relative to the hH3R.
Do Maximizers Predict Better than Satisficers?
Authors: Jain Kriti , Bearden J. Neil , Filipowicz Allan 
Published: October 2011

ABSTRACTWe examine the relationship between maximizing (i.e., seeking the best) versus satisficing (i.e., seeking the good enough) tendencies and forecasting ability in a real‐world prediction task: forecasting the outcomes of the 2010 FIFA World Cup. In Studies 1 and 2, participants gave probabilistic forecasts for the outcomes of the tournament and completed a measure of maximizing tendencies. We found that although maximizers expected themselves to outperform others much more than satisficers, they actually forecasted more poorly. Hence, on net, they were more overconfident about their relative performance. Decompositional analyses of overall accuracy revealed that differences in forecasting abilities were primarily driven by maximizers' tendency to give more noisy estimates. In Study 3, participants played a betting task where they could choose between safe and uncertain gambles linked to World Cup outcomes. Again, maximizers did more poorly and earned less, because of greater noise in their choice‐based responses. Copyright © 2011 John Wiley & Sons, Ltd.
Neurite outgrowth of PC12 cells on diX (parylene) family materials
Authors: Hoshino Takayuki , Saito Itsuro , Takano Haruka , Samejima Kazuyuki , Mabuchi Kunihiko , Kato Yasuhiro X. 
Published: October 2011

AbstractWe investigated neuronal cell differentiation, particularly neurite outgrowth, on the surface of diX H and diX AM using an in vitro examination of a neuron‐like rat pheochromocytoma cell line, PC12. diX H and diX AM are in the parylene family of diX C (or Parylene‐C), which is widely used as a novel coating material to insulate neural electrodes, and they have been recently commercialized; diX H and diX AM offer different features of biocompatibility. Previously, we found that these new parylene materials have high cell adhesiveness to neuronal cells whereas the adhesiveness of diX C is extremely low. However, their cell differentiation remains unknown although neuronal cell differentiation plays a crucial role in their development and regeneration. This study showed that almost all PC12 cells adhering to the surface of diX AM and diX H were differentiated, but the neurite outgrowth was significantly larger on diX H than that on diX AM and a conventional polystyrene culture dish. The result suggests that diX H may be advantageous as a biocompatible coating material for a scaffold, which can be used on virtually any substrate to get various configurations in neural devices. © 2011 American Institute of Chemical Engineers Biotechnol. Prog., 2012
Developments Towards Regioselective Synthesis of 1,2‐Disubstituted Benzimidazoles
Authors: Carvalho Luísa C. R. , Fernandes Eduarda , Marques M. Manuel B. 
Published: October 2011

Abstract1,2‐Disubstituted benzimidazoles play an important role in several areas and particularly as drug discovery targets. Herein, several methods to assemble these structures are reviewed, from the classical approaches to the more recently developed metal‐catalyzed intramolecular amination process, the cascade arylamination/condensation reaction and polymer‐supported benzimidazole assembly under microwave conditions.
Neurofilament phosphorylation regulates axonal transport by an indirect mechanism: A merging of opposing hypotheses
Authors: Shea Thomas B. , Lee Sangmook 
Published: October 2011

AbstractNeurofilaments (NFs) are among the most abundant constituents of the axonal cytoskeleton. NFs consist of four subunits, termed NF‐H, NF‐M and NF‐L, corresponding to heavy, medium and light in reference to their molecular mass and α‐internexin. Phosphorylation of the C‐terminal “sidearms” of NF‐H and NF‐M regulates the ability of NFs to form a cytoskeletal lattice that supports the mature axon. C‐terminal phosphorylation events have classically been considered to regulate NF axonal transport. By contrast, studies demonstrating that NF axonal transport was not accelerated following sidearm deletion provided evidence that phosphorylation does not regulate NF transport. Herein, we demonstrate how comparison of transport and distribution of differentially phosphorylated NFs along axons identify common ground between these hypotheses and may resolve this controversy. © 2011 Wiley Periodicals, Inc.
B‐Ring‐Modified isoCombretastatin A‐4 Analogues Endowed with Interesting Anticancer Activities
Authors: Hamze Abdallah , Rasolofonjatovo Evelia , Provot Olivier , Mousset Céline , Veau Damien , Rodrigo Jordi , Bignon Jérôme , Liu Jian‐Miao , Wdzieczak‐Bakala Joanna , Thoret Sylviane , Dubois Joëlle , Brion Jean‐Daniel , Alami Mouad 
Published: October 2011

AbstractA novel class of isocombretastatin A‐4 (isoCA‐4) analogues with modifications at the 3′‐position of the B‐ring by replacement with C‐linked substituents was studied. Exploration of the structure–activity relationships of theses analogues led to the identification of several compounds that exhibit excellent antiproliferative activities in the nanomolar concentration range against H1299, MDA‐MB231, HCT116, and K562 cancer cell lines; they also inhibit tubulin polymerization with potency similar to that of isoCA‐4. 1,1‐Diarylethylenes 8 and 17, respectively with (E)‐propen‐3‐ol and propyn‐3‐ol substituents at the 3′‐position of the B‐ring, proved to be the most active in this series. Both compounds led to the arrest of various cancer cell lines at the G2/M phase of the cell cycle and strongly induced apoptosis. Docking of compounds 8 and 17 in the colchicine binding site indicated that their C3′ substituents guide the positioning of the B‐ring in a manner different from that observed for isoCA‐4.