bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of models in identification and prediction of physiology in critically ill surgical patients
Authors: Cohen M J 
Published: January 2012

Abstract

Background
With higher-throughput data acquisition and processing, increasing computational power, and advancing computer and mathematical techniques, modelling of clinical and biological data is advancing rapidly. Although exciting, the goal of recreating or surpassing in silico the clinical insight of the experienced clinician remains difficult. Advances toward this goal and a brief overview of various modelling and statistical techniques constitute the purpose of this review.

Methods
A review of the literature and experience with models and physiological state representation and prediction after injury was undertaken.

Results
A brief overview of models and the thinking behind their use for surgeons new to the field is presented, including an introduction to visualization and modelling work in surgical care, discussion of state identification and prediction, discussion of causal inference statistical approaches, and a brief introduction to new vital signs and waveform analysis.

Conclusion
Modelling in surgical critical care can provide a useful adjunct to traditional reductionist biological and clinical analysis. Ultimately the goal is to model computationally the clinical acumen of the experienced clinician.
Social presence and service satisfaction: The moderating role of cultural value‐orientation
Authors: He Yi , Chen Qimei , Alden Dana L. 
Published: January 2012

ABSTRACTTwo studies examine the role of the cultural value orientation, self‐construal, as a moderator of the relationship between social presence and service satisfaction. Cross‐cultural data are collected in China and the USA to maximize variation on self‐construal. Results suggest that social presence effects vary depending on the consumer's independent self‐construal. Regardless of whether the service encounter is positive or negative, social presence increases the strength of satisfaction or dissatisfaction for low independents but not for high independents.Copyright © 2012 John Wiley & Sons, Ltd.
Sequence Determinants Governing the Topology and Biological Activity of a Lasso Peptide, Microcin J25
Authors: Ducasse Rémi , Yan Kok‐Phen , Goulard Christophe , Blond Alain , Li Yanyan , Lescop Ewen , Guittet Eric , Rebuffat Sylvie , Zirah Séverine 
Published: January 2012

AbstractMicrocin J25 is a potent antibacterial peptide produced by Escherichia coli AY25. It displays a lasso structure, which consists of a knot involving an N‐terminal macrolactam ring through which the C‐terminal tail is threaded and sterically trapped. In this study, we rationally designed and performed site‐specific mutations in order to pinpoint the sequence determinants of the lasso topology. Structures of the resulting variants were analysed by a combination of methods (mass spectrometry, NMR spectroscopy, enzymatic digestion), and correlated to the antibacterial activity. The selected mutations resulted in the production of branched‐cyclic or lasso variants. The C‐terminal residues below the ring (Tyr20, Gly21) and the size of the macrolactam ring were revealed to be critical for both the lasso scaffold and bioactivity, while shortening the loop region (Tyr9–Ser18) or extending the C‐terminal tail below the ring did not alter the lasso structure, but differentially affected the antibacterial activity. These results provide new insights for the bioengineering of antibacterial agents using a lasso peptide as template.
ChemInform Abstract: Investigation of Counterion Influence on an Octahedral IrH6‐Complex in the Solid State Hydrides AAeIrH6 (A: Na, K and Ae: Ca, Sr, Ba, and Eu) with a New Structure Type.
Authors: Kadir K. , Moser D. , Muenzel M. , Noreus D. 
Published: January 2012

AbstractThe new title hydrides and the corresponding deuterides are prepared from mixtures of the alkali, alkaline earth, or europium binary hydrides/deuterides, and Ir powder (5 MPa H2/D2, 400 °C).
ChemInform Abstract: Synthesis, Structure and Characterizations of a Novel 3D Coordination Polymer Constructed from Rare Castellated Inorganic Chains.
Authors: Zhai Quan‐Guo , Zhang Cui‐Cui , Li Shu‐Ni , Jiang Yu‐Cheng , Hu Man‐Cheng 
Published: January 2012

AbstractThe new coordination polymer {[Cd8Cl4(trz)12(H2O)] ·2H2O}n (trz: 1,2,4‐triazole) is synthesized from CdCl2, trz, malonic acid, and NaOH under hydrothermal conditions (autoclave, 160 °C, 5 d, 51% yield).
ChemInform Abstract: Layered Assemblies of a Dialuminum‐Substituted Silicotungstate Trimer and the Reversible Interlayer Cation‐Exchange Properties.
Authors: Kikukawa Yuji , Yamaguchi Kazuya , Hibino Mitsuhiro , Mizuno Noritaka 
Published: January 2012

AbstractThe polyoxometallate assemblies (IV) and (VI) are synthesized by trimerization of (III) via μ‐OH bridges and characterized by single crystal XRD.
ChemInform Abstract: Suppression of Realgar Cage Degradation During Complexation: Formation of Hybrid Coordination Polymers with As4S4, PAs3S3, and Cu(I) Halide Building Blocks.
Authors: Schwarz Patrick , Wachter Joachim , Zabel Manfred 
Published: January 2012

AbstractCompounds (VI) crystallize in the monoclinic space group P21/c with Z = 4.
ChemInform Abstract: Iridium‐Catalyzed Allylic Alkylation of Monosubstituted Allylic Acetates with Azlactone, and Separation of Diastereoisomers by Sequential Aza‐Cope Rearrangement.
Authors: Kawatsura Motoi , Tsuji Hiroaki , Uchida Kenta , Itoh Toshiyuki 
Published: January 2012

AbstractThe title reaction of oxazolone (II) with allylic acetates provides a branch‐type product as single diastereomer, whereas the other diastereomer undergoes the rearrangement to a linear alkylation product.
ChemInform Abstract: Enantioselective α‐Arylation of N‐Acyloxazolidinones with Copper(II)‐Bisoxazoline Catalysts and Diaryliodonium Salts.
Authors: Bigot Aurelien , Williamson Alice E. , Gaunt Matthew J. 
Published: January 2012

AbstractA variety of N‐acyloxazolidinones is applied to the reaction with the mesityl(phenyl)iodonium triflate to afford the α‐phenylated products with high yields and enantioselectivities.
ChemInform Abstract: Enantioselective α‐Arylation of Carbonyls via Cu(I)‐Bisoxazoline Catalysis.
Authors: Harvey James S. , Simonovich Scott P. , Jamison Christopher R. , MacMillan David W. C. 
Published: January 2012

AbstractLactones and oxazolidones are effectively α‐arylated using the diaryliodonium hexafluorophosphates and Cu(I)‐‐bisoxazoline catalyst.
ChemInform Abstract: Recyclable Copper Catalysts Based on Imidazolium‐Tagged C2‐Symmetric Bis(oxazoline) and Their Application in D—A Reactions in Ionic Liquids.
Authors: Zhou Zhi‐Ming , et al. et al. 
Published: January 2012

AbstractThe title catalyst shows high activity and enantioselectivity and can be recycled 20 times without significant loss of activity.
ChemInform Abstract: Aerobic Oxidation of Alcohols over Hydrotalcite‐Supported Gold Nanoparticles: The Promotional Effect of Transition Metal Cations.
Authors: Liu Peng , Guan Yejun , van Santen Rutger A. , Li Can , Hensen Emiel J. M. 
Published: January 2012

AbstractHydrotalcite, with all Al3+ replaced by Cr3+, shows strong synergy with Au‐nanoparticles in achieving highly efficient catalysts for the aerobic oxidation of alcohols.
ChemInform Abstract: Impregnated Palladium on Magnetite as Catalyst for Multicomponent Reductive Amination Reactions and Other Related Reducing Processes.
Authors: Cano Rafael , Yus Miguel , Ramon Diego J. 
Published: January 2012

AbstractReductive amination of aromatic and aliphatic aldehydes with primary or secondary amines proceeds smoothly in the system polymethylhydrosiloxane (PMHS)—PdO on magnetite to give the corresponding secondary or tertiary amines in high yields.
ChemInform Abstract: Carbogallation of Alkynes Using Gallium Tribromide and Silyl Ketene Acetals and Synthetic Application to Cross‐Coupling with Aryl Iodides.
Authors: Nishimoto Yoshihiro , Ueda Hiroki , Yasuda Makoto , Baba Akio 
Published: January 2012

AbstractStereoselective carbogallation of alkynes is achieved by simple treatment of GaBr3 with alkynes and ketene silyl acetals.
ChemInform Abstract: A Homogeneous, Recyclable Polymer Support for Rh(I)‐Catalyzed C—C Bond Formation.
Authors: Jana Ranjan , Tunge Jon A. 
Published: January 2012

AbstractThe catalyst efficiently promotes the coupling of aryl‐ and alkenylboronic acids with enones, aldehydes, aldimines, and internal alkynes as well as the hydroformylation of alkenes and the addition of enones to terminal alkynes.
ChemInform Abstract: An Improvement of Nickel Catalyst for Cross‐Coupling Reaction of Arylboronic Acids with Aryl Carbonates by Using a Ferrocenyl Bisphosphine Ligand.
Authors: Kuwano Ryoichi , Shimizu Ryosuke 
Published: January 2012

AbstractAryl carbonates (I) work as electrophilic substrates for the Suzuki—Miyaura reaction under nickel catalysis which is enhanced by the use of a chelate bisphosphine ligand.
ChemInform Abstract: Copper‐Free Sonogashira Coupling Reaction Using a trans‐Spanning 1,2‐Bis(2‐thienylethynyl)benzene Ligand.
Authors: Atobe Shingo , Sonoda Motohiro , Suzuki Yuki , Shinohara Hiroyuki , Yamamoto Takuya , Ogawa Akiya 
Published: January 2012

AbstractThe coupling reaction of aryl halides (I) with terminal acetylenes (II) proceeds in the presence of diethynylbenzene as a trans‐bidentatable ligand.
ChemInform Abstract: A New General Approach for the Stereocontrolled Synthesis of Functionalized γ‐ and δ‐Lactams.
Authors: Daly Mark , Gill Kathryn , Sime Mairi , Simpson Graham L. , Sutherland Andrew 
Published: January 2012

AbstractA general stereoselective synthesis of functionalized γ‐ and δ‐lactams using the Overman rearrangement to install the key C—N bond and a ring closing metathesis reaction to form the ring is developed.
ChemInform Abstract: Base‐Free Two‐Step Synthesis of 1,3‐Diketones and β‐Ketoesters from α‐Diazocarbonyl Compounds, Trialkylboranes, and Aromatic Aldehydes.
Authors: Sanchez‐Carmona Miguel A. , Contreras‐Cruz David A. , Miranda Luis D. 
Published: January 2012

AbstractThe report describes the use of the Hooz reaction/ oxidation sequence as source of various 1,3‐dicarbonyl compounds.
ChemInform Abstract: Formal [3 + 3] Cycloaddition of Silyl Enol Ethers Catalyzed by Triflic Imide: Domino Michael Addition—Claisen Condensation Accompanied with Isomerization of Silyl Enol Ethers.
Authors: Azuma Takumi , Takemoto Yoshiji , Takasu Kiyosei 
Published: January 2012

AbstractA triflimide catalyzed formal [3 + 3] cycloaddition of silyl enol ethers with acrylates is described as a new domino reaction.
ChemInform Abstract: Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1‐Deoxy‐D‐xylulose‐5‐phosphate Reductoisomerase Inhibitors.
Authors: Nordqvist Anneli , Bjoerkelid Christofer , Andaloussi Mounir , Jansson Anna M. , Mowbray Sherry L. , Karlen Anders , Larhed Mats 
Published: January 2012

AbstractThe phosphonic acid derivatives such as (Xa) show potent inhibitory activity.
ChemInform Abstract: Enantioselective Metal‐Free Diamination of Styrenes.
Authors: Roeben Caren , Souto Jose A. , Gonzalez Yolanda , Lishchynskyi Anton , Muniz Kilian 
Published: January 2012

AbstractThe reaction proceeds in the presence of a chiral hypervalent iodine reagent and bismesylamide as N‐source gives generally better results than bistosylimide.
ChemInform Abstract: Monovalent Nickel Complex Bearing a Bulky N‐Heterocyclic Carbene Catalyzes Buchwald—Hartwig Amination of Aryl Halides under Mild Conditions.
Authors: Nagao Shinya , Matsumoto Taisuke , Koga Yuji , Matsubara Kouki 
Published: January 2012

AbstractThe presented Nickel complex catalyzes the title reaction even at previously not reported low temperatures.
ChemInform Abstract: Isolation and Structural Characterization of the Elusive 1:1 Adduct of Hydrazine and Carbon Dioxide.
Authors: Lee Byeongno , Kang Seung Hee , Kang Donghyeon , Lee Kyu Hyung , Cho Jaeheung , Nam Wonwoo , Han Oc Hee , Hur Nam Hwi 
Published: January 2012

AbstractThe zwitterionic form of carbazic acid is isolated as a stable solid and successfully used as a hydrazine replacement in the synthesis of azines (II) and (IV).
ChemInform Abstract: L‐Proline‐Derived Tertiary Amino Alcohols as Chiral Ligands for Enantioselective Addition of Diethylzinc to Aldehydes.
Authors: Xu Zhou , Bo Rongcheng , Wu Nan , Wan Yu , Wu Hui 
Published: January 2012

AbstractIn the presented synthesis the benzaldehyde derivatives with electron‐withdrawing groups give better results than the derivatives with electron‐donating groups.
ChemInform Abstract: CuI/H2/NaOH‐Catalyzed Cross‐Coupling of Two Different Alcohols for Carbon—Carbon Bond Formation: “Borrowing Hydrogen”?
Authors: Miura Takashi , Kose Osamu , Li Feng , Kai Sun , Saito Susumu 
Published: January 2012

AbstractThe present new method for the cross‐coupling of two different alcohols is achieved in the presence of H2 using catalytic amounts of CuBr and NaOH affording longer‐chain alcohols.
ChemInform Abstract: CuBr/FeCl3 Catalysis: A Novel and Efficient Method for the Preparation of New Aryl (Iminomethyl)propargyl Ether Derivatives via C—H Activation of Aryl Propargyl Ethers.
Authors: Kumar Gautham Santhosh , Kurumurthy Chavva , Rao Pillalamarri Sambasiva , Veeraswamy Banda , Rao Pamulaparthi Shanthan , Narsaiah Banda 
Published: January 2012

AbstractSynthesis occurs by C—H activation of aryl propargyl ethers followed by imines generated from aryl aldehydes and aryl amines.
ChemInform Abstract: Palladium‐Catalyzed Mono‐N‐allylation of Unprotected Anthranilic Acids with Allylic Alcohols in Aqueous Media.
Authors: Hikawa Hidemasa , Yokoyama Yuusaku 
Published: January 2012

AbstractPd‐catalyzed treatment of anthranilic acids with allylic alcohols in aqueous solution provides a convenient approach to mono‐N‐allylated anthranilic acids.
ChemInform Abstract: Benzoic Acid Catalyzed Aldol‐Type Condensation of Aldehydes with Ethyl Diazoacetate: Highly Diastereoselective Products with Chiral Aldehydes.
Authors: Krishna Palakodety Radha , Prapurna Y. Lakshmi , Alivelu Munagala 
Published: January 2012

AbstractTitle reaction proceeds for a wide range of aliphatic and aromatic aldehydes under neat conditions to give the product alcohols in high to excellent yields.
ChemInform Abstract: Highly Active Bifunctional SalenTi(IV) Catalysts for Asymmetric Cyanosilylation of Aldehydes and TMSCN.
Authors: Wen Ye Qian , Ren Wei Min , Lu Xiao Bing 
Published: January 2012

AbstractThe use of ligand SAP produces the cyanhydrins (III) with up to 70% e.e.
ChemInform Abstract: Carboxylic Acids as Traceless Directing Groups for Formal meta‐Selective Direct Arylation.
Authors: Cornella Josep , Righi Marika , Larrosa Igor 
Published: January 2012

AbstractThe Pd‐catalyzed ortho‐selective direct arylation of benzoic acids with aryl iodides is followed by protodecarboxylation to allow the access to various meta‐substituted biaryls as synthetically important subunits.
ChemInform Abstract: Phosphane‐Free Suzuki—Miyaura Coupling of Aryl Imidazolesulfonates with Arylboronic Acids and Potassium Aryltrifluoroborates under Aqueous Conditions.
Authors: Civicos Jose Francisco , Gholinejad Mohammad , Alonso Diego A. , Najera Carmen 
Published: January 2012

AbstractA general phosphane‐free oxime‐palladacycle‐catalyzed cross coupling reaction of electron‐rich, electron‐poor, and hindered aryl imidazolesulfonates (I) with arylboronic acids (II) and potassium aryltrifluoroborates is disclosed.
ChemInform Abstract: Copper‐Catalyzed Conjugate Additions of Alkylboranes to Aryl α,β‐Unsaturated Ketones.
Authors: Ohmiya Hirohisa , Shido Yoshinori , Yoshida Mika , Sawamura Masaya 
Published: January 2012

AbstractConjugate addition products (III) are obtained by treatment of aryl α,β‐unsaturated ketones (II) with in situ prepared alkylboron compounds via alkene hydroboration.
ChemInform Abstract: Palladium‐Catalyzed Cross‐Coupling of Aryl Iodides with β‐Trimethylsiloxy‐α‐diazoesters: A Novel Approach Toward β‐Keto‐α‐arylesters.
Authors: Shu Zhibin , Zhang Ji , Zhang Yan , Wang Jianbo 
Published: January 2012

AbstractIn the presented reaction the β‐trimethylsiloxy group can significantly suppress the direct 1,2‐hydride shift from palladium carbene.
ChemInform Abstract: Ruthenium‐Catalyzed Coupling of Oxabenzonorbornadienes with Alkynes Bearing a Propargylic Oxygen Atom: Access to Stereodefined Benzonorcaradienes.
Authors: Tenaglia Alphonse , Marc Sylvain , Giordano Laurent , De Riggi Innocenzo 
Published: January 2012

AbstractThe diastereoselectivity of the unprecedented coupling reaction depends on the presence of substituents on the bridgehead positions of the substrates.
ChemInform Abstract: Palladium‐Catalyzed Direct C—H Bond Arylation of Simple Arenes with Aryltrimethylsilanes.
Authors: Funaki Kenji , Kawai Hiroshi , Sato Tetsuo , Oi Shuichi 
Published: January 2012

AbstractFor the presented reaction CuCl2 is essential to obtain the desired cross‐coupling products in high selectivity.
ChemInform Abstract: Diastereo‐ and Enantioselective Construction of γ‐Butenolides Through Chiral Phosphane‐Catalyzed Allylic Alkylation of Morita—Baylis—Hillman Acetates.
Authors: Wei Yin , Ma Guang‐Ning , Shi Min 
Published: January 2012

AbstractAllylic alkylation of MBH acetates with silyloxyfuran (II) proceeds efficiently in the presence of a novel chiral amidobinaphthylphosphine organocatalyst to afford the products in excellent diastereo‐ and enantioselectivities (< 95% diastereoselectivity, up to 98% e.e.).
ChemInform Abstract: Enantioselective and Regioselective Friedel—Crafts Alkylation of Pyrroles with Nitroalkenes Catalyzed by a Tridentate Schiff Base—Copper Complex.
Authors: Guo Fengfeng , Chang Dalu , Lai Guoyin , Zhu Tao , Xiong Shunshun , Wang Sujing , Wang Zhiyong 
Published: January 2012

AbstractA new chiral catalyst system based on a central Cu2O2 four‐membered ring is used for asymmetric Friedel—Crafts alkylations of pyrroles with nitroalkenes.
ChemInform Abstract: Selective Catalytic Monoreduction of Phthalimides and Imidazolidine‐2,4‐diones.
Authors: Das Shoubhik , Addis Daniele , Knoepke Leif R. , Bentrup Ursula , Junge Kathrin , Brueckner Angelika , Beller Matthias 
Published: January 2012

AbstractThe new protocol produces the target products (II).
ChemInform Abstract: Synthesis of Fused Imidazoles, Pyrroles, and Indoles with a Defined Stereocenter α to Nitrogen Utilizing Mitsunobu Alkylation Followed by Palladium‐Catalyzed Cyclization.
Authors: Laha Joydev K. , Cuny Gregory D. 
Published: January 2012

AbstractAdditionally, the synthesis of some achiral analogues such as (XVIII) is described.
ChemInform Abstract: A Simple One‐Pot Synthesis of N‐Alkyl‐2,5‐diaryl‐1,3‐dioxol‐4‐amines.
Authors: Bayat Mohammad , Nasri Shima 
Published: January 2012

AbstractTitle compounds are synthesized by reaction of various aromatic aldehydes (II) with alkyl isocyanides (I) under neutral conditions.
ChemInform Abstract: Piperidine‐Mediated Synthesis of Thiazolyl Chalcones and Their Derivatives as Potent Antimicrobial Agents.
Authors: Venkatesan P. , Maruthavanan T. 
Published: January 2012

AbstractAmong the investigated compounds, the derivative (IVc) exhibits the highest relative antibacterial, derivative (IVe) the highest relative antifungal activity.
ChemInform Abstract: Click Chemistry from Organic Halides, Diazonium Salts and Anilines in Water Catalyzed by Copper Nanoparticles on Activated Carbon.
Authors: Alonso Francisco , Moglie Yanina , Radivoy Gabriel , Yus Miguel 
Published: January 2012

AbstractOxidized copper nanoparticles on carbon effectively catalyze the multicomponent regioselective synthesis of 1,4‐disubstituted 1,2,3‐triazoles in water at low catalyst loading.
ChemInform Abstract: Multicomponent Click Synthesis of 1,2,3‐Triazoles from Epoxides in Water Catalyzed by Copper Nanoparticles on Activated Carbon.
Authors: Alonso Francisco , Moglie Yanina , Radivoy Gabriel , Yus Miguel 
Published: January 2012

AbstractCu nanoparticles on activated carbon efficiently promote the coupling of epoxides with terminal alkynes and NaN3 to produce β‐hydroxytriazoles with high regio‐ and stereoselectivity.
ChemInform Abstract: Inverse Electron‐Demand 1,3‐Dipolar Cycloaddition of Nitrile Oxide with Common Nitriles Leading to 3‐Functionalized 1,2,4‐Oxadiazoles.
Authors: Nishiwaki Nagatoshi , Kobiro Kazuya , Hirao Shotaro , Sawayama Jun , Saigo Kazuhiko , Ise Yumiko , Okajima Yoshikazu , Ariga Masahiro 
Published: January 2012

AbstractOxadiazoles (III) and (V) are obtained by 1,3‐dipolar cycloaddition of nitril oxide, prepared in situ from (I), with common nitriles.
ChemInform Abstract: Domino Rhodium‐Catalyzed Alkyne Arylation/Palladium‐Catalyzed N‐Arylation: A Mechanistic Investigation.
Authors: Panteleev Jane , Zhang Lei , Lautens Mark 
Published: January 2012

AbstractThe Rh‐catalyzed addition of arylboronic acids to propargylic sulfonamides affords acrylic sulfonamides.
ChemInform Abstract: Synthesis of Phenanthridinones and Phenanthridine Derivatives Through Palladium‐Catalyzed Oxidative C—H Coupling of Benzanilides.
Authors: Ishida Naoki , Nakanishi Yuuta , Moriya Taisaku , Murakami Masahiro 
Published: January 2012

AbstractUnder the presented reaction conditions for the synthesis of the phenanthridinones (II) bromo and cyano substituents are not tolerated.
ChemInform Abstract: Introduction of Two Anthracene Moieties into Perylenebis(dicarboximide) Core by Suzuki—Miyaura Coupling Toward Construction of Donor—Acceptor Arrays.
Authors: Iwanaga Tetsuo , Ida Hiroko , Takezaki Makoto , Toyota Shinji 
Published: January 2012

AbstractThe optical and electrochemical properties of the new stable and colored compounds (IV) and (V) are investigated in CHCl3 and in CH2Cl2, respectively.
ChemInform Abstract: Ruthenium‐Catalyzed Acylation of Arylpyridines with Acyl Chlorides via ortho‐Selective C—H Bond Cleavage.
Authors: Kochi Takuya , Tazawa Aoi , Honda Kazuki , Kakiuchi Fumitoshi 
Published: January 2012

AbstractThe title reaction proceeds under oxidant‐free conditions.
ChemInform Abstract: Synthesis, Biological Evaluation and Molecular Docking Studies of 1,3,4‐Thiadiazole Derivatives Containing 1,4‐Benzodioxan as Potential Antitumor Agents.
Authors: Sun Juan , Yang Yu‐Shun , Li Wei , Zhang Yan‐Bin , Wang Xiao‐Liang , Tang Jian‐Feng , Zhu Hai‐Liang 
Published: January 2012

AbstractCompound (Ic) shows the most potent biological activity against HEPG2 cancer cell line, which is comparable to the positive control.
ChemInform Abstract: Synthesis and Antibacterial Evaluation of Some New 4‐Substituted‐3‐aryl‐1‐(2,6‐dimethylpyrimidin‐4‐yl)pyrazoles.
Authors: Kumar Ravi , Nair Reshmi R. , Dhiman Saurabh Sudha , Sharma Jitender , Prakash Om 
Published: January 2012

AbstractCompounds (IIIb) and (IIIe) exhibit equipotent activity against Gram‐negative bacteria to streptomycin and chloramphenicol.
ChemInform Abstract: Nickel‐Catalyzed sp2 C—H Bonds Arylation of N‐Aromatic Heterocycles with Grignard Reagents at Room Temperature.
Authors: Qu Gui‐Rong , Xin Peng‐Yang , Niu Hong‐Ying , Wang Dong‐Chao , Ding Rui‐Fang , Guo Hai‐Ming 
Published: January 2012

AbstractA novel protocol for Ni‐catalyzed direct sp2 C—H bond arylation of purines (I) is described.
ChemInform Abstract: Synthesis of 4‐(1‐Phenyl‐1H‐pyrazol‐3‐yl)‐[1,2,4]triazolo[4,3‐a]quinoxalines and Their 4‐Halogenopyrazolyl Analogues.
Authors: Atta Kamal F. M. , El Ashry El Sayed H. 
Published: January 2012

AbstractWith a view to their potential biological activity the title compounds, e.g. (III), (IX), (XI), and (XIII), are prepared.
ChemInform Abstract: Rapid Photoassisted Access to N,O,S‐Polyheterocycles with Benzoazocine and Hydroquinoline Cores: Intramolecular Cycloadditions of Photogenerated Azaxylylenes.
Authors: Mukhina Olga A. , Kumar N. N. Bhuvan , Arisco Teresa M. , Valiulin Roman A. , Metzel Greg A. , Kutateladze Andrei G. 
Published: January 2012

AbstractNovel photocycloaddition reactions of o‐azaxylylenes, generated by excited‐state intramolecular proton transfer from o‐amidoaryl aldehydes and ketones, result in the stereoselective formation of polycyclic [4 + 2] and [4 + 4] adducts.