bluuebunny/crossref_metadata_2025_split huggingface dataset:
The benefits of an offline to online cognitive behavioral stress management regarding anxiety, depression, spiritual well‐being, and quality of life in postoperative intrahepatic cholangiocarcinoma patients
Authors: Liu Yueping , Xu Xin , Ye Xiaoyan 
Published: June 2024

AbstractAimCognitive behavioral stress management (CBSM) has been introduced for the postoperative cancer management, but its application in intrahepatic cholangiocarcinoma (ICC) is rare. This current study constructed an offline to online CBSM (OO‐CBSM) program and applying multiple assessing scales, aiming at exploring the benefits of OO‐CBSM regarding anxiety, depression, spiritual well‐being, and quality of life (QoL) in postoperative ICC patients.MethodsThe study randomly assigned 68 postoperative ICC patients into OO‐CBSM (N = 34) and normal care (NC) (N = 34) groups to undergo 10‐week interventions. Hospital anxiety‐and‐depression scale (HADS), Zung's self‐reporting anxiety scale (SAS), and depression scale (SDS), functional‐assessment of chronic‐illness therapy‐spiritual well‐being scale (FACIT‐Sp), European quality‐of‐life‐5 dimensions (EQ‐5D), and quality‐of‐life questionnaire‐core30 (QLQ‐C30) were assessed within 6 months (M).ResultsHADS‐anxiety scores at M3 (P = 0.049) and M6 (P = 0.009), SAS score at M6 (P = 0.028), HADS‐depression score at M3 (P = 0.043), and SDS scores at M3 (P = 0.044) and M6 (P = 0.028), were lower in the OO‐CBSM group versus the NC group. Meanwhile, FACIT‐Sp scores at M1 (P = 0.042) and M6 (P = 0.003) were higher in the OO‐CBSM group over the NC group. Besides, EQ‐5D scores at M3 (P = 0.067) and M6 (P = 0.087) disclosed trends to be lower in the OO‐CBSM group versus the NC group, but not statistically significant. QLQ‐C30‐global‐health scores at M3 (P = 0.049) and M6 (P = 0.033), and QLQ‐C30‐function score at M6 (P = 0.046), were higher in OO‐CBSM group over NC group; but QLQ‐C30‐symptom score was not significantly different at any timepoints between them.ConclusionOO‐CBSM attenuates anxiety and depression, and advances spiritual well‐being and QoL in postoperative ICC patients, indicating its potency for the ICC postoperative management.
Interstitial pregnancy: A retrospective case series of surgically managed patients over a ten‐year period
Authors: Van Michelle , Smet Maria‐Elisabeth , Cash Sally , Noori Nargis 
Published: June 2024

AimsTo describe the ultrasound diagnostic features and surgical management procedures for patients with an interstitial ectopic pregnancy in our tertiary institution and associated peripheral hospital over a ten‐year period.MethodsA retrospective audit of all surgically managed cases of interstitial pregnancies over a ten‐year period at a tertiary hospital and one associated peripheral hospital in New South Wales.ResultsSixteen cases of surgically managed interstitial pregnancy were identified. In 43.8% of these cases, patients had previously undergone an ipsilateral salpingectomy. No cases required hysterectomy, post‐operative methotrexate or return to theatre. Ten patients underwent diagnostic ultrasound prior to operative management, seven of which were correctly identified to be an interstitial ectopic pregnancy at the time. The proportion of cornuostomies being performed for interstitial pregnancy compared to wedge resection has increased over the period of this review from 33 to 60% between the two five‐year periods.ConclusionThe combination of expert ultrasound and sophisticated laparoscopic techniques at our institution has facilitated earlier diagnosis and greater use of minimally invasive management of interstitial pregnancy.
Population‐based norms for the human papillomavirus‐quality of life (HPV‐QoL) questionnaire: A cross‐sectional multicenter study
Authors: Calvo‐Torres Javier , Rejas‐Gutiérrez Javier , Ramírez‐Mena Mar , Bradbury Melissa , Del Pino Marta , González‐Granados Carmen , Procas Beatriz , Coronado Pluvio J. ,   HPV‐QoL study group
Published: June 2024

AbstractIntroductionHuman papillomavirus (HPV) diagnosis has a considerable emotional and psychological impact on women. To evaluate the impairment this infection leads to regarding quality of life (QoL), several scales have been suggested, such as the human‐papillomavirus‐quality‐of‐life (HPV‐QoL) questionnaire. This has been validated for the Spanish population and measures the impact of HPV on health‐related‐quality‐of‐life (HR‐QoL). However, normative values are yet to be developed. Thus, the objective was to describe the population‐based norms of the HPV‐QoL for Spanish women aged 25–65 years and to test the questionnaire's construct validity.Material and MethodsThis was a cross‐sectional nationwide multicenter study. Women from outpatient clinics in Spain aged 25–65 years, with a diagnosis of past or active HPV infection were recruited. The central tendency, dispersion, and percentiles were calculated for the total score and its dimensions for each age group. Construct validity was tested by analyzing age groups and their correlations with other related scales (12‐Item General Health Questionnaire [GHQ‐12], Female Sexual Function Index [FSFI], and Hospital Anxiety and Depression Scale [HADS]).ResultsA total of 1352 women were included in the study. The norms showed moderate and significant coefficients of correlation with other related scales. Significant differences between age strata groups were found according to educational level, sexual dysfunction, sexual activity, mental deterioration, and severity of anxiety and depression symptoms (p < 0.001 in all cases). The total score differed significantly between the groups (p = 0.006). Significant differences in the contagiousness, health, and sexuality dimensions (p < 0.05) were found among the groups. It was seen that HPV infection impaired women's QoL. Dimensions within all test age groups (p < 0.001 in all cases) were significantly different, with the health dimension being the highest contributor to women's QoL impairment, whereas social well‐being was the main determinant of QoL.ConclusionsPopulation‐based norms for the novel HPV‐QoL questionnaire showed adequate validity and could be a useful tool for assessing the impact of QoL among women with HPV in Spain.
Euthanasia in detention and the ethics of caring solidarity: A case study of the ‘Tarragona Gunman’
Authors: Espericueta Luis 
Published: June 2024

AbstractAlmost a year after the enactment of the law regulating euthanasia in Spain, public opinion was shocked to learn that a defendant in criminal proceedings obtained medical assistance in dying following injuries sustained in an exchange of gunfire with the police after having committed a series of severe crimes. Although there are very few cases in the world where prisoners have received euthanasia, the one we will discuss in this article is the only known case where both the public prosecutor's office and the private prosecutors judicially opposed the defendant's euthanasia. This article aims to offer a new perspective on the ethical legitimacy of detainees' access to euthanasia: the ethics of caring solidarity. To do this, we will first place the case in its legal context. Subsequently, we will address the two main arguments proposed in the literature to justify euthanasia in detention: respect for the autonomy of the detainee and the principle of equivalence of care. Finally, after having identified serious shortcomings in both arguments, we will argue that the perspective of caring solidarity offers a better ethical basis for people in detention's access to euthanasia.
Post‐pandemic public personnel retention: A person‐organization and person‐supervisor fit analysis
Authors: Deschênes Andrée‐Anne 
Published: June 2024

AbstractThis study examines person/organization and person/supervisor fit of public administration professionals in the context of hybrid work. A three‐phase study was conducted among 411 public professionals in Quebec. Results show that person/organization and person/supervisor fit have declined over time, and that satisfaction with hybrid work played a role in this decline. Person/organization fit affects intention to stay with the public organization. These results show the importance for public organizations to take employees' needs, values and expectations into account to increase satisfaction with the hybrid work experience and foster the retention of public service employees in a post‐pandemic era.
Building resilience in families experiencing homelessness through integration of health, parenting and child development programs
Authors: Edie Alison Hester , Carmody Karen Appleyard , Scott Jewel 
Published: June 2024

AbstractChildren who experience homelessness are vulnerable to mental health problems, developmental delays and lower academic achievement. Research suggests that parental health literacy, sensitive parenting behaviour and child self‐regulation are modifiable mechanisms that might enhance children's resilience to adversities associated with homelessness, yet empirical evidence on implementing such interventions in shelter settings is limited. Through a coordinated academic‐community partnership, this study aimed to examine the (1) feasibility of conducting an integrated health approach in shelter settings and (2) the effectiveness of separate interventions on child and parent outcomes. Results are discussed in terms of best practices in shelter settings and building resilience in families experiencing homelessness with young children.
Plague and local response in North China, 1900–28
Authors: Reeves Caroline 
Published: June 2024

AbstractBreakthroughs in international biomedical science circa 1900 meant that plague could be contained through strict quarantine regulations. These measures were successfully deployed with help from local governments during outbreaks of pneumonic plague in Manchuria (1910–11), Shanxi (1918), and elsewhere in North China. This containment shows the effectiveness of uniting international knowledge and local cooperation in disaster response. Yet, in later outbreaks in similar locations, control measures identical to those instituted a decade earlier were rejected, and plague spread largely unchecked. Historical case studies of the control and spread of infectious disease in North China reveal the complexities of the relationship between global knowledge and its broader, local integration, variation in what constitutes effective ‘local’ cooperation in adopting international knowledge, and the paramount importance of the locality to the landscape of disaster response. History can reveal critical issues in localisation of disaster response still salient today.
Person‐reported outcomes in registered randomised diabetes trials: A mapping review of constructs
Authors: de Wit Maartje , van Luik Selina , Marrero David , Barnard‐Kelly Katharine , Snoek Frank J. 
Published: June 2024

AbstractAimRecently, efforts have been made to use and report person‐reported outcomes (PROs) in randomised clinical trials (RCTs). Here, we aim to (1) assess the status of inclusion of PROs in registered RCTs over 5 years in people with type 1 or 2 diabetes, and (2) map the PRO measures (PROMs) onto predefined domains.MethodsThe largest trial registries (Clinicatrials.gov, International Clinical Trial Platform and ISRCTN) were systematically searched for RCTs in people with type 1 and/or type 2 diabetes of all ages between 2018 and 2023. Coding of PROs comprised: (1) PRO measure(s) included yes or no; if yes: (2) PRO(s) as primary outcome yes or no; and (3) mapping PROMs onto predefined PRO domains and per type of intervention.ResultsN = 1543 trials met our inclusion criteria, of which n = 673 (44%) included PROs, assessed by 545 different measures. Twenty per cent of drug trials (n = 112) and 71% of behavioural interventions (n = 405) included PROs. In 149 trials (9.6%), a PRO was the primary outcome. The psychological functioning domain was most often assessed across all trials (21.6%), specifically in behavioural (44.8%) and medical device interventions (29.7%). In drug trials, the physical functioning and functional health domain was most included (9%). Across all trials, the social and family functioning domain was least assessed (3%).ConclusionsWe noticed an increase in the inclusion of PROs in diabetes RCTs. However, PROs are rarely included as primary outcomes in the majority of studies, particularly in drug trials. The heterogeneity of PROMs used in RCTs underscores the need for standardisation of PROs.
Juxtacellular recordings from identified neurons in the mouse locus coeruleus
Authors: Zouridis Ioannis S. , Schmors Lisa , Fischer Kathrin Maite , Berens Philipp , Preston‐Ferrer Patricia , Burgalossi Andrea 
Published: June 2024

AbstractThe locus coeruleus (LC) is the primary source of noradrenergic transmission in the mammalian central nervous system. This small pontine nucleus consists of a densely packed nuclear core—which contains the highest density of noradrenergic neurons—embedded within a heterogeneous surround of non‐noradrenergic cells. This local heterogeneity, together with the small size of the LC, has made it particularly difficult to infer noradrenergic cell identity based on extracellular sampling of in vivo spiking activity. Moreover, the relatively high cell density, background activity and synchronicity of LC neurons have made spike identification and unit isolation notoriously challenging. In this study, we aimed at bridging these gaps by performing juxtacellular recordings from single identified neurons within the mouse LC complex. We found that noradrenergic neurons (identified by tyrosine hydroxylase, TH, expression; TH‐positive) and intermingled putatively non‐noradrenergic (TH‐negative) cells displayed similar morphologies and responded to foot shock stimuli with excitatory responses; however, on average, TH‐positive neurons exhibited more prominent foot shock responses and post‐activation firing suppression. The two cell classes also displayed different spontaneous firing rates, spike waveforms and temporal spiking properties. A logistic regression classifier trained on spontaneous electrophysiological features could separate the two cell classes with 76% accuracy. Altogether, our results reveal in vivo electrophysiological correlates of TH‐positive neurons, which can be useful for refining current approaches for the classification of LC unit activity.
Oxidation protection of tri‐layer La2Zr2O7/Yb2Si2O7/SiC‐coated Cf/SiC composites at high temperature
Authors: Chen Pengju , Xiao Peng , Tian Tian , Li Yang 
Published: June 2024

AbstractYtterbium silicate (Yb2Si2O7) and lanthanum zirconate (La2Zr2O7) ceramic powders were synthesized by the sol–gel method. A novel tri‐layer La2Zr2O7/Yb2Si2O7/SiC environmental barrier coating was prepared on the surface of C/SiC composites to improve the service temperature of the coating (above the Si melting point, 1683 K). Results show that both Yb2Si2O7 and La2Zr2O7 ceramic powders had extremely high purity and were accompanied by a large number of nanoparticles. The tri‐layer La2Zr2O7/Yb2Si2O7/SiC coating can efficiently prevent the oxidation failure of C/SiC composites in 1773 K air environment for more than 100 h with slight weight loss of 5.71 × 10−3 g·cm−2 and the matching weight loss rate of 5.71 × 10−5 g·cm−2·h−1. No significant chemical reaction was observed between Yb2Si2O7 middle and La2Zr2O7 outer coatings during the oxidation process at 1773 K, indicating that the tri‐layer La2Zr2O7/Yb2Si2O7/SiC coating had better oxidation stability in 1773 K air environment.
Equivalence between direct and indirect measures of psychological capital
Authors: Alessandri Guido , Filosa Lorenzo 
Published: June 2024

AbstractPsychological Capital (PsyCap) represents an individual's positive and resourceful state, defined by high levels of self‐efficacy, optimism, hope, and resiliency. Since its inception, extensive research has focused on exploring the factors influencing and outcomes associated with PsyCap within organizational contexts. Consequently, there has been a growing demand for reliable assessment tools to measure PsyCap accurately. The present multi‐study investigation aimed to examine whether the two main measures of Psychological Capital, namely the Psychological Capital Questionnaire and the Implicit‐Psychological Capital Questionnaire, show convergence in measuring the same underlying construct. In Study 1, using data from 327 employees from whom we obtained both self‐ and coworker reports on both explicit and implicit Psychological Capital, we evaluated the degree of convergence between measures using a Multitrait‐Multimethod approach. In Study 2, we used six‐wave longitudinal data from 354 employees, gathered every week for 6 consecutive weeks, to test a series of STARTS models, to decompose the proportions of variance of all the components (i.e., trait, state and error) of both Psychological Capital measures, and to compare their magnitude and similarity. In this second study, we also compared their longitudinal predictive power with respect to important organizational outcomes (i.e., work engagement and emotional exhaustion). All in all, results provided empirical evidence for the high degree of convergence of explicit and implicit measures of Psychological Capital. Implications and potential applications of our findings are discussed.
The need for “Considered Estimation” versus “Conservative Estimation” when ranking or comparing predictors of job performance
Authors: Bobko Philip , Roth Philip L. , Huy Le , Oh In‐Sue , Salgado Jesus 
Published: June 2024

AbstractA recent attempt to generate an updated ranking for the operational validity of 25 selection procedures, using a process labeled “conservative estimation” (Sackett et al., 2022), is flawed and misleading. When conservative estimation's treatment of range restriction (RR) is used, it is unclear if reported validity differences among predictors reflect (i) true differences, (ii) differential degrees of RR (different u values), (iii) differential correction for RR (no RR correction vs. RR correction), or (iv) some combination of these factors. We demonstrate that this creates bias and introduces confounds when ranking (or comparing) selection procedures. Second, the list of selection procedures being directly compared includes both predictor methods and predictor constructs, in spite of the substantial effect construct saturation has on validity estimates (e.g., Arthur & Villado, 2008). This causes additional confounds that cloud comparative interpretations. Based on these, and other, concerns we outline an alternative, “considered estimation” strategy when comparing predictors of job performance. Basic tenets include using RR corrections in the same manner for all predictors, parsing validities of selection methods by constructs, applying the logic beyond validities (e.g., ds), thoughtful reconsideration of prior meta‐analyses, considering sensitivity analyses, and accounting for nonindependence across studies.
The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy
Authors: McCulloch Timothy R , Rossi Gustavo R , Miranda‐Hernandez Socorro , Valencia‐Hernandez Ana Maria , Alim Louisa , Belle Clemence J , Krause Andrew , Zacchi Lucia F , Lam Pui Yeng , Nakamura Kyohei , Kupz Andreas , Wells Timothy J , Souza‐Fonseca‐Guimaraes Fernando 
Published: June 2024

AbstractAntibiotic resistance is a major public health threat, and alternatives to antibiotic therapy are urgently needed. Immunotherapy, particularly the blockade of inhibitory immune checkpoints, is a leading treatment option in cancer and autoimmunity. In this study, we used a murine model of Salmonella Typhimurium infection to investigate whether immune checkpoint blockade could be applied to bacterial infection. We found that the immune checkpoint T‐cell immunoglobulin and ITIM domain (TIGIT) was significantly upregulated on lymphocytes during infection, particularly on CD4+ T cells, drastically limiting their proinflammatory function. Blockade of TIGIT in vivo using monoclonal antibodies was able to enhance immunity and improve bacterial clearance. The efficacy of anti‐TIGIT was dependent on the capacity of the antibody to bind to Fc (fragment crystallizable) receptors, giving important insights into the mechanism of anti‐TIGIT therapy. This research suggests that targeting immune checkpoints, such as TIGIT, has the potential to enhance immune responses toward bacteria and restore antibacterial treatment options in the face of antibiotic resistance.
Prevention of anthracycline and trastuzumab‐induced decline in left ventricular ejection fraction with angiotensin‐converting enzyme inhibitors or angiotensin receptor blocker: a narrative systematic review of randomised controlled trials
Authors: Lee Simon , Alsamarrai Ammar , Xiao Amy , Wang Tom K. M. 
Published: June 2024

AbstractCancer therapy‐related cardiac dysfunction (CTRCD) is a complication of selected cancer therapy agents associated with decline in left ventricular ejection fraction (LVEF). Angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) have established benefits in heart failure with reduced ejection fraction, but their efficacy for preventing CTRCD remains controversial. This narrative systematic review assessed the efficacy and safety of ACEI/ARB in the prevention of cancer therapy LVEF decline. We systematically searched PubMed, Embase and Cochrane from January 1980 to June 2022. Studies of interest were randomised controlled trials of patients with normal LVEF and active malignancy receiving cancer therapy, randomised to receive either an ACEI or ARB compared with a control group. The outcome was the change in LVEF from baseline to the end of the follow‐up period. Death, clinical heart failure and adverse drug reactions were recorded. A total of 3731 search records were screened and 12 studies were included, comprising a total of 1645 participants. Nine studies assessed the prevention of anthracycline‐induced LVEF decline, of which five showed a beneficial effect (1%–14% higher LVEF in treated groups), whereas four studies showed no effect. Three studies assessed the prevention of trastuzumab‐induced LVEF decline, of which one showed a beneficial effect (4% higher LVEF) in a subset of participants. There are mixed data regarding the efficacy of ACEI/ARB in preventing the LVEF decline in patients undergoing anthracycline or trastuzumab therapy, with evidence suggesting no clinically meaningful benefit observed in recent studies.