bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Maillard reaction conditions on the antigenicity of bovine α‐lactalbumin using response surface methodology
Authors: Bu Guanhao , Lu Jing , Zheng Zhe , Luo Yongkang 
Published: August 2009

AbstractBACKGROUND: Maillard reaction can modify functional properties of proteins. Bovine α‐lactalbumin (α‐LA) is often supplemented to the new generation of infant formulae, but it is considered to be a main allergen. However, there is little information on the effect of Maillard reaction on α‐LA antigenicity. The objective of this study was to investigate the influence of Maillard reaction on the antigenicity of α‐LA in conjugates of whey protein isolate (WPI) with glucose under different conditions of protein/sugar weight ratio (0.17–7.83), temperature (40–60 °C) and time (24–120 h) using response surface methodology.RESULTS: Conjugation of WPI with glucose markedly reduced the antigenicity of α‐LA. This reduction in antigenicity could be controlled by regulating the three independent variables weight ratio, temperature and time. A model of optimal reaction conditions for lower antigenicity of α‐LA was established. According to the model, the minimum antigenicity of α‐LA was achieved at 52.8 °C, 78 h and 5.96:1 WPI/glucose weight ratio. WPI/glucose weight ratio had the greatest effect on the antigenicity of α‐LA, while reaction temperature influenced α‐LA antigenicity to a lesser extent.CONCLUSION: Well‐controlled Maillard reaction between WPI and glucose is an efficient method to reduce α‐LA antigencity. Copyright © 2009 Society of Chemical Industry
Hemostatic Efficacy of Biological Self‐Assembling Peptide Nanofibers in a Rat Kidney Model
Authors: Song Hong , Zhang Lanlan , Zhao Xiaojun 
Published: August 2009

AbstractWe evaluated the hemostatic efficacy of a biological self‐assembling peptide RADA16‐I in a rat kidney injury model. Adult male rats were randomized into five groups: sham operation (no renal excision), no hemostatic agent (control), commercially available gelatin sponge (Gelfoam), 1% RADA16‐I, and 2% RADA16‐I. After left partial nephrectomy, the anesthetized animal was anticoagulated using 300 IU · kg−1 heparin, and the topical hemostatic agent was applied to the injury. Blood loss and mean arterial pressure (MAP) were recorded. As was the case for Gelfoam, 2% RADA16‐I produced marked hemostasis versus controls (p < 0.01). Blood loss with 1% and 2% RADA16‐I was significantly less than controls. The decline in MAP during surgery was less with 2% versus 1% RADA16‐I. RADA16‐I also resulted in less histological tissue responses than Gelfoam. These data suggest that RADA16‐I can stop hemorrhage, with only minimal tissue responses, in experimental renal injury.magnified image
Initiation of chloride‐induced corrosion of steel in concrete: role of the interfacial zone
Authors: Page C. L. 
Published: August 2009

AbstractThis paper provides a brief review of research aimed at characterising the steel–concrete interfacial zone (SCIZ) and its influence on the susceptibility of the metal to pitting corrosion when concrete is exposed to environments that cause ingress of chloride ions accompanied by leaching of hydroxyl ions. For reinforced concrete made from Portland cements, exposed to aqueous solutions of sodium chloride, the buffering effect of solid calcium hydroxide (portlandite) at pH ∼12.6 has been shown to restrain the gradual decline in the hydroxyl ion concentration of the concrete pore solution phase at depths corresponding to the embedded steel. When the concrete is produced under laboratory conditions that are carefully controlled to exclude macroscopic defects from the SCIZ and the steel is cleaned before being embedded, this can lead to observed chloride threshold levels being consistently greater than 1% chloride by mass of cement. The buffering action of cement hydration products formed in the SCIZ is believed to be partly responsible for this high tolerance to chloride‐induced corrosion because it counters the generation of ‘anodic acidity’ that is a necessary condition for stable growth of pits to occur. Translating this behaviour of laboratory specimens to the performance of full‐scale reinforced concrete structures has often proved difficult in the past and there is a need for further research in this area, particularly in relation to the role of non‐traditional cements.
Analysis of the variability of chloride threshold values in the literature
Authors: Alonso M. C. , Sanchez M. 
Published: August 2009

AbstractEfforts are being devoted in standards and construction codes in order to give rules and guidelines for designing durable structures. Also efforts are focused in developing the models in a more accurate approach to the calculation of the service life of concrete structures. Service life models consider that reinforced concrete exposed to chloride polluted environments initiate corrosion when a certain amount of chlorides arrives to the rebar surface. The so‐called chloride threshold level is considered as an essential parameter for assessing the probability of reinforcement corrosion, and becomes one of the key parameters needed for service life prediction, being of interest to have testing methods and expressions to introduce in the models. Numerous studies have been carried out to establish a critical chloride level for the onset of corrosion, but a wide range of chloride threshold values has been suggested which makes not feasible to define a single value. Present paper includes the analysis of the variability of the chloride threshold values published in the literature. Data from mortar and concrete and from laboratory and field exposure are compiled and included in the analysis. The influence of the testing method used for determination and several variables are considered.
Poly(sulfonated phenylene)‐block‐Polyimide Copolymers for Fuel Cell Applications
Authors: Bi Huiping , Chen Shouwen , Chen Xinbing , Chen Kangcheng , Endo Nobutaka , Higa Mitsuru , Okamoto Kenichi , Wang Lianjun 
Published: August 2009

AbstractNovel poly(2‐(3‐sulfo)benzoyl‐1,4‐phenylene)‐block‐polynaphthalimide (PSP‐b‐PI) copolymers were successfully synthesized by Ni(0)‐catalyzed copolymerization of 2,5‐dichloro‐3′‐sulfo‐benzophenone and dichloro‐terminated naphthalimide oligomer. The membranes exhibited a microphase‐separated structure and good hydrolytic stability at 130 °C. They showed a fairly strong anisotropy of membrane swelling with much smaller in‐plane swelling, but a rather weak anisotropy of proton conductivity. The membranes had a fairly high through‐plane conductivity in water and even under low relative humidity. The PSP‐b‐PI copolymer with an IEC of 1.5 meq · g−1 showed high PEFC performance due to the high through‐plane conductivity.magnified image
Tremor in 48,XXYY syndrome
Authors: Tartaglia Nicole , Borodyanskya Mariya , Hall Deborah A. 
Published: August 2009

AbstractThe 48,XXYY syndrome is a form of sex chromosome aneuploidy presenting in 1:18,000 males. Tremor has been previously reported in 47,XXY and 47,XYY syndromes, but has not been well described in 48,XXYY syndrome. Ten males with 48,XXYY syndrome had a standardized neurological examination and videotaping, which included the Clinical Rating Scale for Tremor and the International Cooperative Ataxia Rating Scale. All 10 cases had postural and kinetic tremor on physical examination. Other findings included mild gait ataxia, dysarthria, and nystagmus. Three cases are reviewed. Tremor is a common finding in children and young adults with 48,XXYY syndrome. Dosage alteration of genes on the sex chromosomes may be involved in the pathogenesis of this tremor. Karyotyping should be considered in individuals presenting with tremor and a history of developmental delay, learning disabilities, tall stature, or microorchidism. © 2009 Movement Disorder Society
Cognitive disturbances in primary blepharospasm
Authors: Alemán Gabriela Gonzalez , de Erausquin Gabriel A. , Micheli Federico 
Published: August 2009

AbstractThe common belief that primary dystonia is a purely motor disorder with no anatomical substrate and no other accompanying neurological dysfunction has recently been challenged. In addition, there is increasing evidence that the basal ganglia besides motor control, plays a role in cognitive functioning. However, no systematic cognitive performance evaluation has been carried out in patients with primary blepharospasm (BS), one of the most common forms of adult dystonia. We evaluated a series of 20 patients with primary BS and a group of 17 controls matched by severity of mood symptoms, age, and sex. BS patients performed significantly worse on the Luria sequencing test, Purdue pegboard test, reciprocal coordination, tactile denomination, and reverse visuospatial span and the differences persisted after correction for age, duration of disease, severity of BS, and degree of depression. The Wisconsin card sorting test showed no statistical difference, but BS patients made more errors and more perseverative answers than expected according to population means, whereas the control group performed poorly but within normal parameters. Our findings suggest broad cortical involvement in focal dystonia that is not correlated with the severity or duration of dystonia. © 2009 Movement Disorder Society
Meta‐analyses of agreement between diagnoses made from clinical evaluations and standardized diagnostic interviews
Authors: Rettew David C. , Lynch Alicia Doyle , Achenbach Thomas M. , Dumenci Levent , Ivanova Masha Y. 
Published: August 2009

AbstractStandardized diagnostic interviews (SDIs) have become de facto gold standards for clinical research. However, because clinical practitioners seldom use SDIs, it is essential to determine how well SDIs agree with clinical diagnoses. In meta‐analyses of 38 articles published from 1995 to 2006 (N = 15,967 probands), mean kappas (z‐transformed) between diagnoses from clinical evaluations versus SDIs were 0.27 for a broad category of all disorders, 0.29 for externalizing disorders, and 0.28 for internalizing disorders. Kappas for specific disorders ranged from 0.19 for generalized anxiety disorder to 0.86 for anorexia nervosa (median = 0.48). For diagnostic clusters (e.g. psychotic disorders), kappas ranged from 0.14 for affective disorders (including bipolar) to 0.70 for eating disorders (median = 0.43). Kappas were significantly higher for outpatients than inpatients and for children than adults. However, these effects were not significant in meta‐regressions. Conclusions: Diagnostic agreement between SDIs and clinical evaluations varied widely by disorder and was low to moderate for most disorders. Thus, findings from SDIs may not fully apply to diagnoses based on clinical evaluations of the sort used in the published studies. Rather than implying that SDIs or clinical evaluations are inferior, characteristics of both may limit agreement and generalizability from SDI findings to clinical practice. Copyright © 2009 John Wiley & Sons, Ltd.
Sensitivity and specificity of univariate MRI analysis of experimentally degraded cartilage
Authors: Lin Ping‐Chang , Reiter David A. , Spencer Richard G. 
Published: August 2009

AbstractMRI is increasingly used to evaluate cartilage in tissue constructs, explants, and animal and patient studies. However, while mean values of MR parameters, including T1, T2, magnetization transfer rate km, apparent diffusion coefficient (ADC), and the dGEMRIC‐derived fixed charge density, correlate with tissue status, the ability to classify tissue according to these parameters has not been explored. Therefore, the sensitivity and specificity with which each of these parameters was able to distinguish between normal and trypsin‐degraded, and between normal and collagenase‐degraded, cartilage explants were determined. Initial analysis was performed using a training set to determine simple group means to which parameters obtained from a validation set were compared. T1 and apparent diffusion coefficient showed the greatest ability to discriminate between normal and degraded cartilage. Further analysis with k‐means clustering, which eliminates the need for a priori identification of sample status, generally performed comparably. Use of fuzzy c‐means (FCM) clustering to define centroids likewise did not result in improvement in discrimination. Finally, an FCM clustering approach in which validation samples were assigned in a probabilistic fashion to control and degraded groups was implemented, reflecting the range of tissue characteristics seen with cartilage degradation. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.
Effects of unilateral electromyostimulation superimposed on voluntary training on strength and cross‐sectional area
Authors: Bezerra Pedro , Zhou Shi , Crowley Zachary , Brooks Lyndon , Hooper Andrew 
Published: August 2009

AbstractIn this study we investigate the effects of unilateral voluntary contraction (VC) and electromyostimulation superimposed on VC (EV) training on maximal voluntary (MVC) force and cross‐sectional area (CSA), as assessed by magnetic resonance imaging of knee extensors. Thirty young men were randomly assigned to either a control group (CG), VC group (VG), or EV group (EVG). The VG and EVG trained the right leg isometrically three sessions per week for 6 weeks. After training, MVC increased in the right leg in the VG and in both legs in the EVG, and EVG was significantly different from CG (all P < 0.01). Increased CSA was found only in the right leg in the VG and EVG (P < 0.01), and correlated with improvements of MVC (r = 0.49, P = 0.01). It appeared that the EV training was equally effective as VC at increasing MVC and CSA, while having a greater cross‐education effect. Increased strength without muscle hypertrophy in the unexercised leg of the EVG indicated that neural adaptation was responsible for the cross‐education effect. Muscle Nerve 40: 430–437, 2009
New product introduction against a predator: A bilevel mixed‐integer programming approach
Authors: Smith J. Cole , Lim Churlzu , Alptekinoğlu Aydın 
Published: August 2009

AbstractWe consider a scenario with two firms determining which products to develop and introduce to the market. In this problem, there exists a finite set of potential products and market segments. Each market segment has a preference list of products and will buy its most preferred product among those available. The firms play a Stackelberg game in which the leader firm first introduces a set of products, and the follower responds with its own set of products. The leader's goal is to maximize its profit subject to a product introduction budget, assuming that the follower will attempt to minimize the leader's profit using a budget of its own. We formulate this problem as a multistage integer program amenable to decomposition techniques. Using this formulation, we develop three variations of an exact mathematical programming method for solving the multistage problem, along with a family of heuristic procedures for estimating the follower solution. The efficacy of our approaches is demonstrated on randomly generated test instances. This article contributes to the operations research literature a multistage algorithm that directly addresses difficulties posed by degeneracy, and contributes to the product variety literature an exact optimization algorithm for a novel competitive product introduction problem. © 2009 Wiley Periodicals, Inc. Naval Research Logistics, 2009
Morley type non‐C0 nonconforming rectangular plate finite elements on anisotropic meshes
Authors: Shi Dongyang , Xie Pingli 
Published: August 2009

AbstractIn this article, two Morley type non‐C0 nonconforming rectangular finite elements are discussed to numerically solve the fourth order plate bending problem under anisotropic meshes. The optimal anisotropic interpolation error and consistency error estimates are obtained by using some novel approaches. Some numerical tests are given to confirm the theoretical analysis. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
A numerical study of 2D integrated RBFNs incorporating Cartesian grids for solving 2D elliptic differential problems
Authors: Mai‐Duy N. , Tran‐Cong T. 
Published: August 2009

AbstractThis article reports a numerical discretization scheme, based on two‐dimensional integrated radial‐basis‐function networks (2D‐IRBFNs) and rectangular grids, for solving second‐order elliptic partial differential equations defined on 2D nonrectangular domains. Unlike finite‐difference and 1D‐IRBFN Cartesian‐grid techniques, the present discretization method is based on an approximation scheme that allows the field variable and its derivatives to be evaluated anywhere within the domain and on the boundaries, regardless of the shape of the problem domain. We discuss the following two particular strengths, which the proposed Cartesian‐grid‐based procedure possesses, namely (i) the implementation of Neumann boundary conditions on irregular boundaries and (ii) the use of high‐order integration schemes to evaluate flux integrals arising from a control‐volume discretization on irregular domains. A new preconditioning scheme is suggested to improve the 2D‐IRBFN matrix condition number. Good accuracy and high‐order convergence solutions are obtained. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Application of adapted homotopy perturbation method for approximate solution of Henon‐Heiles system
Authors: Taşcan Filiz , Özer Mehmet Naci 
Published: August 2009

AbstractWe performed adapted homotopy perturbation method on the Henon‐Heiles system with the help of the symbolic computation of package Maple 10 (User Manual by Maplesoft. www.maplesoft.com). We obtained a new approximate solution of the Henon‐Heiles system. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Numerical investigation of the solution of Fisher's equation via the B‐spline Galerkin method
Authors: Dağ İdris , Şahin Ali , Korkmaz Alper 
Published: August 2009

AbstractThe Galerkin method is used with quadratic B‐spline base functions to obtain the numerical solutions of Fisher's equation which is a one dimensional reaction‐diffusion equation. To observe the effects of reaction and diffusion, four test problems related to pulse disturbance, step disturbance, super‐speed wave and strong reaction are studied. A comparison is performed between the obtained numerical results and some earlier studies. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2010
Development and initial psychometric evaluation of the Patient Perspective of Arrhythmia Questionnaire
Authors: Wood Kathryn A. , Stewart Anita L. , Drew Barbara J. , Scheinman Melvin M. , Frolicher Erika S. 
Published: August 2009

AbstractThere are no disease‐specific questionnaires to measure patient sensitive outcomes in arrhythmia patients. We report the development and preliminary psychometric testing of the Patient Perception of Arrhythmia Questionnaire (PPAQ). The PPAQ was developed using formative research, exploratory factor analysis, expert review, pilot study, and regression. The PPAQ measures frequency and duration of episodes, symptoms, impact on daily activities, and restricted activity days. After preliminary content validation, the sensitivity of the PPAQ was tested in 103 arrhythmia patients. The measures showed good sensitivity and reliability. Preliminary construct validation was supported by significant differences (p < .001) among groups of arrhythmia patients consistent with clinical patterns. Preliminary evidence from patients with supraventricular arrhythmias suggests that the questionnaire has acceptable psychometrics and could be useful in future studies of arrhythmia patients. © 2009 Wiley Periodicals, Inc. Res Nurs Health 32:504–516, 2009
Occupational therapy students' attitudes towards inclusion education in Australia, United Kingdom, United States and Taiwan
Authors: Mu Keli , Brown Ted , Peyton Claudia G. , Rodger Sylvia , Huang Yan‐Hua , Wu Chin‐Yu , Watson Callie , Stagnitti Karen , Hutton Eve , Casey Jackie , Hong Chia Swee 
Published: August 2009

AbstractThis international, cross‐cultural study investigated the attitudes of occupational therapy students from Australia, United Kingdom, United States and Taiwan towards inclusive education for students with disabilities. The possible impact of professional education on students' attitudes was also explored. A total of 485 students from 11 entry‐level occupational therapy education programmes from Australia, the United Kingdom, the United Sates and Taiwan participated in the study. Among them, 264 were freshmen (first‐year students) and 221 were seniors (final‐year students). Data collected from a custom‐designed questionnaire were analysed both quantitatively and qualitatively.In general, the occupational therapy students reported having positive attitudes towards inclusion. Considerable differences, however, existed among the student groups from the four countries. Professional education appeared to have a significant impact on students' attitudes towards inclusion from first year to senior year. Although students were in favour of inclusion, they also cautioned that their support for inclusive practices depended on various factors such as adequate preparation, support and assistance to students with disabilities.Limitations of the study included the small, convenience sample and different degree structures of the participating programmes. Future research studies need to compare occupational therapy students' attitudes with students from other health care professions. A longitudinal study on the impact of the professional education programme on students' attitudes towards inclusive education is warranted. Copyright © 2009 John Wiley & Sons, Ltd.
Mechanical properties and foaming behavior of cellulose fiber reinforced high‐density polyethylene composites
Authors: Kuboki Takashi , Lee Yoon H. , Park Chul B. , Sain Mohini 
Published: August 2009

AbstractThis article investigates the effects of fiber length and maleated polymers on the mechanical properties and foaming behavior of cellulose fiber reinforced high‐density polyethylene composites. The results from the mechanical tests suggested that long fibers provided higher flexural and impact properties than short fibers. In addition, the maleated high‐density polyethylene increased flexural strength significantly, while the maleated thermoplastic elastormers increased notched Izod impact strength dramatically. On the other hand, the results from the extrusion foaming indicated that the composites with long and short fibers demonstrated similar cell morphology, i.e., a similar average cell size and cell size distribution. However, the addition of maleated high‐density polyethylene caused an increase of the average cell size and cell size distribution in the composites. POLYM. ENG. SCI., 2009. © 2009 Society of Plastics Engineers
Extraction and characterization of natural cellulose fibers from common milkweed stems
Authors: Reddy Narendra , Yang Yiqi 
Published: August 2009

AbstractNatural cellulose fibers with cellulose content, strength, and elongation higher than that of milkweed floss and between that of cotton and linen have been obtained from the stems of common milkweed plants. Although milkweed floss is a unique natural cellulose fiber with low density, the short length and low elongation make milkweed floss unsuitable as a textile fiber. The possibility of using the stems of milkweed plant as a source for natural cellulose fibers was explored in this research. Natural cellulose fibers extracted from milkweed stems have been characterized for their composition, structure, and properties. Fibers obtained from milkweed stems have about 75% cellulose, higher than the cellulose in milkweed floss but lower than that in cotton and linen. Milkweed stem fibers have low % crystallinity when compared with cotton and linen but the strength of the fibers is similar to cotton and elongation is higher than that of linen fibers. POLYM. ENG. SCI., 2009. © 2009 Society of Plastics Engineers