bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of nanosilica on the morphology, thermal and mechanical properties of polyurethane elastomer
Authors: Lučić Blagojević Sanja , Buhin Zrinka , Pustak Anđela , Lukić Kovačić Ružica 
Published: December 2011

AbstractIn this article, the influence of fumed silica nanofiller on the structure and properties of segmented polyurethane elastomer (PUR) was investigated. In order to investigate the interactions at the filler–matrix interface, nonmodified and commercially modified fillers (with methacrylsilane and octylsilane) were used. The PUR composites with 1.0, 2.0, 4.0, 6.0, and 9.0 vol % of all fillers were prepared by solution casting method. Surface free energy of the fillers and polymer matrix was determined using contact angle measurements with different testing liquids. Change in morphology was analyzed using optical polarization microscopy and distribution of the filler in polymer matrix using scanning electron microscopy. The influences of silica fillers on mechanical and thermal properties of PUR were investigated. Results showed that surface treatment of silica filler with methacrylsilane and octylsilane reduces the agglomeration of particles that improves dispersion at microlevel. Addition of all fillers disrupts spherulite morphology and decreases crystallinity of the PUR matrix. Nonmodified silica nanofiller has the least pronounced influence on spherulite morphology and the lowest influence on polyurethane crystallinity and thus the best mechanical properties. Surface modification of silica with octylsilane has less influence on polyurethane crystallinity and on decreasing of mechanical properties than modification with methacrylsilane. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
ChemInform Abstract: Synthesis and Characterization of the Phosphorus Triazides OP(N3)3 and SP(N3)3.
Authors: Zeng Xiaoqing , Bernhardt Eduard , Beckers Helmut , Willner Helge 
Published: December 2011

AbstractThe two explosive compounds (II) and (IV) can be handled in gas, liquid, and solid states in submillimolar quantities.
ChemInform Abstract: Synthesis, Structure and Magnetism of a 2‐D Organic—Inorganic Hybrid Tetra‐Co(II)‐Substituted Sandwich‐Type Keggin Germanotungstate: {[Co(dap)2(H2O)]2 [Co(dap)2]2 [Co4(Hdap)2 (B‐α‐HGeW9O34)2]}·7 H2O.
Authors: Chen Lijuan , Shi Dongying , Zhao Junwei , Wang Yulong , Ma Pengtao , Niu Jingyang 
Published: December 2011

AbstractThe title compound (dap: 1,2‐diaminopropane) is hydrothermally synthesized from a mixture of K8Na2[A‐α‐GeW9O34], CoCl2, PrCl3, dap, H2O, and glacial acetic acid (autoclave, 160 °C, 7 d, 37% yield).
ChemInform Abstract: Tandem Catalytic Allylic Amination and [2,3]‐Stevens Rearrangement of Tertiary Amines.
Authors: Soheili Arash , Tambar Uttam K. 
Published: December 2011

AbstractAllylic carbonates and tertiary amine nucleophiles undergo palladium‐catalyzed formation of ammonium ylides which subsequently rearrange to amino acid derivatives or complex α‐amino ketones with unprecedented levels of diastereocontrol.
ChemInform Abstract: New Example of a Dihydrothiazine—Thiazoline Rearrangement in the Bromination of 4‐Allyl‐5‐methyl‐1,2,4‐triazole‐3‐thione.
Authors: Kim D. G. , Il'inykh E. S. 
Published: December 2011

AbstractThe thiazolo[3,1‐b]thiazinium salt (III) is probably the result of a dihydrothiazine‐thiazoline rearrangement proceeding via intermediary thiiranium ion formation.
ChemInform Abstract: Stereospecific Palladium‐Catalyzed Decarboxylative C(sp3)—C(sp2) Coupling of 2,5‐Cyclohexadiene‐1‐carboxylic Acid Derivatives with Aryl Iodides.
Authors: Chou Chih‐Ming , Chatterjee Indranil , Studer Armido 
Published: December 2011

AbstractPalladium‐catalyzed decarboxylative arylation of 2,5‐cyclohexadiene‐1‐carboxylic acids (I) with aryl iodides proceeds smoothly to give 5‐arylated 1,3‐cyclohexadienes (III) in good yields.
ChemInform Abstract: PBu3‐Mediated Vinylogous Wittig Reaction of α‐Methyl Allenoates with Aldehydes and Mechanistic Investigations.
Authors: Xu Silong , Chen Rongshun , He Zhengjie 
Published: December 2011

AbstractSlow addition of allenoates of type (I) to aldehydes and α,β‐unsaturated aldehydes in the presence of PBu3 allows facile and highly stereoselective access to trisubstituted 1,3‐dienes and 1,3,5‐trienes.
ChemInform Abstract: Alum [KAl(SO4)2·12H2O]: An Efficient, Novel, Clean, Catalyst for Doebner—Knoevenagel Reaction for the Efficient Production of α,β‐Unsaturated Acids.
Authors: Suresh Suresh , Kumar Dhruva , Sandhu Jagir S. 
Published: December 2011

AbstractThe method is fairly general and applicable to heterocyclic aldehydes such as (IV) and (VI).
ChemInform Abstract: Rapid and Highly Efficient Trimethylsilylation of Alcohols and Phenols with Hexamethyldisilazane (HMDS) Catalyzed by in situ Generated I2 Using Oxone®/KI or Cerium Ammonium Nitrate (CAN)/KI Systems under Mild Conditions.
Authors: Kolvari Eskandar , Khazaei Ardeshir , Zolfigol Mohammad Ali , Koukabi Nadiya , Gilandoust Maryam , Bakhit Neda 
Published: December 2011

AbstractStructurally diverse alcohols and phenols are trimethylsilylated conveniently using iodine generated in situ from CAN/KI or Oxone/KI systems as catalyst.
ChemInform Abstract: Ti/Pd‐Promoted Intramolecular Michael‐Type Addition of Allylic Carboxylates to Activated Alkenes.
Authors: Millan Alba , Martin‐Lasanta Ana , Miguel Delia , Alvarez de Cienfuegos Luis , Cuerva Juan M. 
Published: December 2011

AbstractBesides carbonates, acetates and benzoate work as leaving group, too.
ChemInform Abstract: Metal‐Free Aerobic Oxidative Coupling of Amines to Imines.
Authors: Liu Lianghui , Zhang Siyu , Fu Xuefeng , Yan Chun‐Hua 
Published: December 2011

AbstractOptimal reaction conditions are established for the catalyst‐free transformation of amines (IV) into imines (V) and (VII) in aqueous media.
ChemInform Abstract: An Efficient and Recyclable Magnetic‐Nanoparticle‐Supported Palladium Catalyst for the Suzuki Coupling Reactions of Organoboronic Acids with Alkynyl Bromides.
Authors: Zhang Xiuli , Li Pinhua , Ji Yong , Zhang Lei , Wang Lei 
Published: December 2011

AbstractThe procedure allows the use of various aliphatic and aromatic alkynes as well as different types of boron substrates to prepare symmetrical and unsymmetrical acetylenes.
ChemInform Abstract: Deprotonative Metalation of Aromatic Compounds by Using an Amino‐Based Lithium Cuprate.
Authors: Nguyen Tan Tai , Marquise Nada , Chevallier Floris , Mongin Florence 
Published: December 2011

AbstractAn effective protocol using lithium cuprates, based on the reaction with [(TMP)2CuLi], generated in situ, is disclosed.
ChemInform Abstract: Highly Diastereo‐ and Enantioselective NHC‐Catalyzed [3 + 2] Annulation of Enals and Isatins.
Authors: Sun Li‐Hui , Shen Li‐Tao , Ye Song 
Published: December 2011

AbstractA series of spirocyclic lactones (III) is prepared with good diastereo‐ and enantioselectivities by reaction of isatins (I) with enals (II) in the presence of a chiral N‐heterocyclic carbene.
ChemInform Abstract: One‐Pot Approach for the Synthesis of 2‐Aryl Benzothiazoles via a Two‐Component Coupling of gem‐Dibromomethylarenes and o‐Aminothiophenols.
Authors: Siddappa Chandrappa , Kambappa Vinaya , Umashankara Muddegowda , Rangappa Kanchugarakoppal S. 
Published: December 2011

AbstractThe convenient procedure allows the preparation of various title compounds in good yields.
ChemInform Abstract: Utilization of 2‐Halo‐1,3,4‐thiadiazoles in the Synthesis of 2‐Functionalized 1,3,4‐Thiadiazole Derivatives.
Authors: Wang Xi‐Cun , Luo Jin‐Ge , Ding Xiao‐Mei , Quan Zheng‐Jun 
Published: December 2011

AbstractNovel 2‐halo‐5‐aryloxymethyl‐thiadiazoles (II) are prepared by diazotization of aminothiadiazoles (I) in the presence of an acid‐catalyst under copper‐free conditions.
ChemInform Abstract: Facile Synthesis of Substituted Pyrrole‐Fused Isocoumarins from Ninhydrin.
Authors: Pathak Sudipta , Kundu Ashis , Pramanik Animesh 
Published: December 2011

AbstractThe route involves the stepwise condensation of acetylacetone with amines and ninhydrin followed by acid‐catalyzed rearrangement.
ChemInform Abstract: Chiral (Acyclic diaminocarbene)gold(I)‐Catalyzed Dynamic Kinetic Asymmetric Transformation of Propargyl Esters.
Authors: Wang Yi‐Ming , Kuzniewski Christian N. , Rauniyar Vivek , Hoong Christina , Toste F. Dean 
Published: December 2011

AbstractThe title reaction of phenol‐substituted propargyl pivalates (I) or (III) proceeds via a formal [3,3] sigmatropic rearrangement followed by a 6‐endo‐trig cyclization to give enantioenriched 2‐substituted chromenyl pivalates.
ChemInform Abstract: Synthetic Versatility in C—H Oxidation: A Rapid Approach to Differentiated Diols and Pyrans from Simple Olefins.
Authors: Gormisky Paul E. , White M. Christina 
Published: December 2011

AbstractThe method for the intramolecular C—H oxidation of various carboxylic acids bearing an alkene moiety affords the dioxanones with moderate to good anti‐selectivities.
ChemInform Abstract: Synthesis of New Dihydropyrimidinones Catalyzed by Dicationic Ionic Liquid.
Authors: Jawale Dhanaji V. , Pratap Umesh R. , Mulay Aparna A. , Mali Jyotirling R. , Mane Ramrao A. 
Published: December 2011

AbstractTitle compounds (IV) are conveniently synthesized by a one‐pot multicomponent Biginelli reaction using a dicationic ionic liquid as medium and catalyst.
ChemInform Abstract: Synthesis and Antibacterial Activities of New Dibenzothiazepine Derivatives.
Authors: Mahale Ganesh D. , Kolekar Yogesh M. , Kumar Ashok , Singh Dharmendra , Kodam Kisan M. , Waghmode Suresh B. 
Published: December 2011

AbstractThe newly synthesized dibenzothiazepines (III) are evaluated for their activity against both Gram‐positive and Gram‐negative bacteria.
ChemInform Abstract: Synthesis of New α‐Glucosidase Inhibitors Based on Oleanolic Acid Incorporating Cinnamic Amides.
Authors: Nie Wei , Luo Jian‐Guang , Wang Xiao‐Bing , Yin Hong , Sun Hong‐Bin , Yao He‐Quan , Kong Ling‐Yi 
Published: December 2011

AbstractA series of α‐glucosidase inhibitors (I) with an oleanolic acid core and different cinnamic amide ligands are designed and synthesized.
ChemInform Abstract: A Novel and Efficient One‐Pot Synthesis of Symmetrical Diamide (Bis‐amidate) Prodrugs of Acyclic Nucleoside Phosphonates and Evaluation of Their Biological Activities.
Authors: Jansa Petr , Janeba Zlatko , et al. et al. 
Published: December 2011

AbstractDiamide prodrugs (IIIa) and (Va) exhibit anti‐HIV activities at submicromolar concentrations with minimal cytotoxicity.
ChemInform Abstract: Total Syntheses of (Sp)‐(+)‐ and (Rp)‐(‐)‐Spiniferin‐1, a Pair of Unusual Natural Products with Planar Chirality
Authors: Sun Yun‐Shan , Ding Kai , Tian Wei‐Sheng 
Published: December 2011

Abstractvia a palladium‐catalyzed β‐H elimination reaction of ester (I) and a perfluorobutanesulfonyl fluoride induced homoallylic carbocation rearrangement as key steps
ChemInform Abstract: Synthesis, Antimicrobial Activity and Possible Mechanism of Action of 9‐Bromo‐Substituted Indolizinoquinoline‐5,12‐dione Derivatives.
Authors: Wu Xi‐Wei , Wu Zu‐Ping , Wang Lu‐Xia , Zhang Hong‐Bin , Chen Jian‐Wen , Zhang Wei , Gu Lian‐Quan , Huang Zhi‐Shu , An Lin‐Kun 
Published: December 2011

Abstract25 Title compounds of type (I) are prepared and tested for their antimicrobial activities against 9 bacterial strains.
ChemInform Abstract: Synthesis, Biological Assessment and Molecular Modeling of New Multipotent MAO and Cholinesterase Inhibitors as Potential Drugs for the Treatment of Alzheimer′s Disease.
Authors: Samadi Abdelouahid , Marco‐Contelles Jose , et al. et al. 
Published: December 2011

Abstract11 Compounds of type (I) are subjected to pharmacological evaluation.
Microparticle formation after co‐culture of human whole blood and umbilical artery in a novel in vitro model of flow
Authors: Holtom Emma , Usherwood James R. , Macey Marion G. , Lawson Charlotte 
Published: December 2011

AbstractCardiovascular disease (CVD) is now the largest killer in western society, and the importance of interactions between vascular endothelium and circulating blood components in disease pathogenesis is well established. Microparticles are a heterogeneous population of <1 μm blood borne particles that arise from blebbing or shedding of cell membranes. The microparticle population includes several classes of apoptotic bodies; however, increased numbers of procoagulant microparticles have been described in plasma from people with CVD. We have previously demonstrated that interactions of monocytes and platelets with isolated inflamed endothelial cells lead to production of pro‐coagulant tissue factor bearing microparticles under laminar flow conditions. Here we have investigated microparticle production after perfusion of human whole blood through intact inflamed human umbilical artery. When blood was perfused through umbilical arteries which had been pre‐stimulated with tumour necrosis factor (TNFα) for 18 h under flow conditions, there was significantly increased production of microparticles from both platelet and non‐platelet sources, in particular from erythrocytes. To determine whether microparticles generated during interactions with inflamed endothelium could induce a pro‐inflammatory response in trans, we isolated microparticles by centrifugation after co‐culture and incubated with isolated quiescent endothelial cells followed by measurement of reactive oxygen species formation. Microparticles derived from co‐culture with inflamed endothelium induced significantly enhanced levels of reactive oxygen species (ROS). These data suggest that presence of an inflamed endothelium causes release of pro‐inflammatory microparticles from circulating blood cells, which could contribute to prolonged endothelial activation and subsequent atherosclerotic changes in blood vessels subjected to inflammatory insult. © 2011 International Society for Advancement of Cytometry
The need for littermate controls
Authors: Holmdahl Rikard , Malissen Bernard 
Published: December 2011

AbstractThe dramatic increase in the amount of research data being produced necessarily leads to higher demands on statistical thresholds and on experimental planning. This is to avoid positive selection of multiple tested data. Here we would like to highlight the need for including littermate controls in animal experiments, in particular when genetically modified strains are analysed for quantitative phenotypes. Thus, this suggestion will have impact on most immunological experiments performed today.
Synthesis of β‐Hydroxy and β‐Amino Ketones from Allylic Alcohols Catalyzed by Ru(η5‐C5Ph5)(CO)2Cl
Authors: Bartoszewicz Agnieszka , Jeżowska Martina M. , Laymand Kévin , Möbus Juri , Martín‐Matute Belén 
Published: December 2011

AbstractAn efficient method for the synthesis of β‐hydroxy and β‐amino ketones from allylic alcohols catalyzed by Ru(η5‐C5Ph5)(CO)2Cl is described. The influence of the stereoelectronic properties of the catalyst on the reaction outcome has been studied. Optimization of the reaction conditions supressed the formation of undesired side products such as saturated ketones, benzyl alcohols, and α,β‐unsaturated ketones. Several aromatic and aliphatic allylic alcohols have been reacted with a large variety of aldehydes or imines to produce β‐hydroxy ketones or β‐amino ketones, respectively, in yields up to 99 %. Based on experimental data, a mechanism via ruthenium alkoxides and ruthenium aldoxides is proposed. In addition, a C‐bound ruthenium enolate has been characterized.
The Roots of Individuality: Contempt Has Brought About Its Factual Disappearance
Authors: Carrel Alexis 
Published: December 2011

It is a commonplace among vocational counselors that effective guidance depends upon knowledge of the individual and of the environment. Probably no one knows more about the mechanism of the human body than Alexis Carrel, noted surgeon and Nobel Prize winner, yet he proclaims that “our ignorance is profound.” But while lamenting the fact that “we are the victims of the sciences of life over those of matter,” we take courage in the succeeding assertion that “the only possible remedy for this evil is a much more profound knowledge of ourselves.”The following quotations from his stirring book, Man the Unknown, reprinted by permission of the publishers, Harper and Brothers, make direct or indirect reference to the relationship between the human being and the work he has to do in the world. That constitutes, as Dr. Carrel would say, a primary datum of observation in the professional equipment of the vocational counselor. In fact, the entire book is a basic piece of literature in the science and philosophy of vocational guidance. The reader may and will, at times, disagree violently with the author, but can never ignore him.
Placement of the Tuberculous
Authors: PERSONS W. FRANK 
Published: December 2011

“… I am one of the millions of citizens who have had Tb. After years spent in the cure I am now told that I have an arrested case, which means a cure, and that I can work at suitable employment. That is the rub—suitable employment!“I was a construction foreman—a job that requires physical exertion and contact with all kinds of weather. I know no other kind of work. If I attempt this kind of work I am told the result is likely to be another breakdown—whereas if I will do office work or {take one of} the many positions that are in existence that require little physical {muscular} exertion, I have a chance to expect reasonably long life with the self‐respect of earning my living.“But I haven't a chance. No one will hire a man who has had Tb. … No one wants us around them even though we are cured with no activity that could possibly spread the disease. Before leaving the sanatorium I worked twelve hours a day as night orderly with fifty‐two patients, seven days a week. I did this for six months without any harmful effects as to health. …“What chance have I? I went into a sanatorium at thirty years of age and after what is termed by the celebrities who have Tb. ‘a heroick fight’ which is really a lot of hooey—the fight being the natural desire to live—I find myself at forty‐one discharged as cured and dependent on my aged father and mother who have to struggle to make a living when they could have been on easy street in their old age but for me…“I hope you can help me and the literally millions of tuberculars and former tuberculars to find some way to earn a living.”
Pittsburgh Accepts the Challenge
Authors: RULE JAMES N. , GRAHAM BEN G. 
Published: December 2011

Pittsburgh for many years has been interested in the problems of occupational adjustment. It was with heightened interest, therefore, that I participated in the recent NOC Occupational Education Tour for School Superintendents.Immediate application of major recommendations made by members of the Tour, published in the June number of OCCUPATIONS, was accomplished in Pittsburgh schools in the late spring and early summer months of 1937. Nearly two years ago our Board of Education provided for a Committee to Study High Schools. The purpose was to bring to the consideration of problems involving the future development of the schools the benefit of the best judgment and experience of the teaching and supervisory staff. The study group represents a cross‐section of our instructional and administrative forces, and gives teachers opportunity to participate in the constructive criticism of existing policies, and the development of new policies.Under the chairmanship of James N. Rule, the committee meeting all day each Monday during the school year, and each week day during the entire month of July, has achieved much in reorganizing and rebuilding our high school program. Especially is this true with respect to matters pertaining to the various phases of Occupational Adjustment, as related by Dr. Rule in the accompanying article. In addition to regular meetings of the committee, special general conferences have been held to which were invited leading laymen and women, local educational leaders, members of the administrative staff, and the high school principals. Outstanding outside educational leaders addressed some of these conferences and consulted with the committee. These included Fred C. Smith, University of Tennessee, Secretary of the National Vocational Guidance Association; Edwin A. Lee, Director, National Occupational Conference; Earl W. Barnhart, United States Office of Education; Herbert E. Hawkes, Columbia University; W. C. Reavis, University of Chicago; and John W. Withers, New York University.
Army Instruments of Individual Appraisal
Authors: HAYS CAPTAIN CREIGHTON E. 
Published: December 2011

In addition to the tests universally used in classifying men in the Army (see “Every Man in the Right Place,” Lieut. George P. Warner, Occupations, Oct., 1941, p. 3), there are other tests used by different organizations within the Army for a variety of purposes. The Army Air Corps, for example, uses a group of aptitude and achievement tests in selecting recruits for its technical schools. A Weather Aptitude Test, a combination of general mental ability and physics achievement test, has been found to have a high correlation with grades of students who attend the Weather Observers School. A special battery of clerical tests is used in selecting students for the special Air Corps Clerical School. Shop mathematics is covered in another test and is used as a part of the general Mechanical battery. Tests of the surface development and mechanical movements types are also included. Parachute riggers, Link Trainer service men, airplane mechanics, weather observers, photographers, radio operators are all selected for training partially upon the basis of test scores.The factor of interest is probably given greater consideration in the selection of men for the Air Corps than in any other branch of the service. Men entering the Air Corps are informed about the different courses and the nature of the work. If they have a high school education and their score on the Army General Classification Test is at the 50th percentile or above, they may choose the technical school they wish to attend. Aptitude and achievement tests are used to verify the wisdom of a man's choice. Only when the odds are hopelessly against success in his chosen school is he encouraged to make a different choice.
Digital imaging in pathology – current applications and challenges
Authors: Brachtel Elena , Yagi Yukako 
Published: December 2011

AbstractConventional histopathology is rapidly shifting towards digital integration. Will microscopes (and pathologists) soon be obsolete? Or are we dealing with just another image modality that leaves the core of tissue diagnosis intact? This article provides an overview of current digital pathology applications and research with emphasis on whole slide imaging (WSI). Static or interactive digital pathology work stations already can be used for many purposes, e.g. telepathology expert consultations, frozen section diagnosis in remote areas, cytology screening, quality assurance, diagnostic validations for clinical trials, quantitation of hormone receptor or HER2 studies in breast cancer, or three‐dimensional visualization of anatomical structures, among others. Changes of workflow in histology laboratories are beginning to enable digital image acquisition and WSI in a routine setting. WSI plays an increasing role in pathology education, glass slide boxes in medical schools are being replaced by digital slide collections; digital slide seminars and virtual microscopy are used for postgraduate and continuing medical education in pathology. Research and efforts to validate WSI systems for diagnostic settings are ongoing. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)