bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Vitamin D with Cardiovascular Disease
Authors: Faisal Ramzan , Ali Saad Abu Bakar 
Published: May 2024

Objective: To investigate the relationship between vitamin D level in serum and cardiovascular diseases.
Study Design: Prospective study.
Place and duration: Study was conducted in Choudhary Parvez Ellahi institute of cardiology in one year duration from 1st February 2020 to 1st February 2021.
Methodology: One hundred and fifty patients presented with cardiac illness at emergency department were enrolled in study. Serum vitamin D hydroxyl level was divided into three categories deficiency, insufficiency and deficiency. SPSS version 23 was used for fata analysis. P value ≤0.5 was taken as significant.
Results: Serum 25(OH) D levels in both the groups were shown in table. III. In the non-CVD Group, 48% of patients were deficient. 56% of patients were insufficient and n=30 (40%) patients were sufficient serum level. While, in CVD Group, n=44 (58.6%) patients were deficient. 37.3% of patients were insufficient, and 61.3% patients were sufficient serum level. The differences were statistically significant.
Conclusion: Serum 25-hydroxy vitamin D at lower values associated with increased cardiovascular diseases. Further studies are needed to recommend vitamin D supplements to reduce the risk of cardiovascular diseases.
Hubungan Tingkat Pengetahuan Dengan Sikap Masyarakat Dalam Memberikan Pertolongan Pada Korban Henti Jantung
Authors: Deswita Reny 
Published: May 2024

Latar Belakang: angka kematian akibat henti jantung masih sangat tinggi, yaitu sekitar 475.000 kasus kematian. Kondisi henti jantung wajib diberi pertolongan secepatnya karena menyebabkan sirkulasi darah keseluruh tubuh dapat terganggu. Masyarakat umum memiliki sangat berperan dalam memberikan pertolongan pertama pada korban henti jantung yang terjadi di luar rumah sakit. Tujuan: mengetahui hubungan antara tingkat pengetahuan dengan sikap masyarakat dalam memberi pertolongan pada pasien henti jantung di RW 04 Kelurahan Batu Ceper. Metode: menggunakan rancangan penelitian Cross Sectional, sampel 93 responden, melalui purposive sampling technique, data didapatkan dengan memberikan kuesioner kepada responden yang kemudian diolah dengan uji analisis Rank Spearman. Hasil: tingkat pengetahuan kurang sebanyak 45 orang (48,4%) dengan sikap buruk masyarakat sebanyak 56 orang (60,2%). Terdapat hubungan yang signifikan antara tingkat pengetahuan dan sikap masyarakat dengan nilai p value (0,000) < α (0,05). Kesimpulan: semakin tinggi tingkat pengetahuan masyarakat, maka akan semakin baik sikapnya dalam memberikan pertolongan kepada pasien henti jantung.
Assessment of medical information on irritable bowel syndrome information in Wikipedia and Baidu Encyclopedia: comparative study
Authors: Li Xi , Chen Kexin , Jia Yongbin , Yin Fang , Wen Xi , Wang Chunhui , Li Zhipeng , Zhang Hu 
Published: May 2024

Background
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder (FGID) with heterogeneous clinical presentations. There are no clear testing parameters for its diagnosis, and the complex pathophysiology of IBS and the limited time that doctors have to spend with patients makes it difficult to adequately educate patients in the outpatient setting. An increased awareness of IBS means that patients are more likely to self-diagnose and self-manage IBS based on their own symptoms. These factors may make patients more likely to turn to Internet resources. Wikipedia is the most popular online encyclopedia among English-speaking users, with numerous validations. However, in Mandarin-speaking regions, the Baidu Encyclopedia is most commonly used. There have been no studies on the reliability, readability, and objectivity of IBS information on the two sites. This is an urgent issue as these platforms are accessed by approximately 1.45 billion people.

Objective
We compared the IBS content on Wikipedia (in English) and Baidu Baike (in Chinese), two online encyclopedias, in terms of reliability, readability, and objectivity.

Methods
The Baidu Encyclopedia (in Chinese) and Wikipedia (in English) were evaluated based on the Rome IV IBS definitions and diagnoses. All possible synonyms and derivatives for IBS and IBS-related FGIDs were screened and identified. Two gastroenterology experts evaluated the scores of articles for both sites using the DISCERN instrument, the Journal of the American Medical Association scoring system (JAMA), and the Global Quality Score (GQS).

Results
Wikipedia scored higher overall with DISCERN (p < .0001), JAMA (p < .0001) and GQS (p < .05) than the Baidu Encyclopedia. Specifically, Wikipedia scored higher in DISCERN Section 1 (p < .0001), DISCERN Section 2 (p < .01), DISCERN Section 3 (p < .001), and the General DISCERN score (p < .0001) than the Baidu Encyclopedia. Both sites had low DISCERN Section 2 scores (p = .18). Wikipedia also had a larger percentage of high quality scores in total DISCERN, DISCERN Section 1, and DISCERN Section 3 (p < .0001, P < .0001, P < .0004, respectively, based on the above 3 (60%) rule).

Conclusions
Wikipedia provides more reliable, higher quality, and more objective IBS-related health information than the Baidu Encyclopedia. However, there should be improvements in the information quality for both sites. Medical professionals and institutions should collaborate with these online platforms to offer better health information for IBS.
The videofluoroscopic swallowing study shows a sustained improvement of dysphagia in children with Niemann–Pick disease type C after therapy with miglustat
Authors: Fecarotta Simona , Amitrano Michele , Romano Alfonso , Della Casa Roberto , Bruschini Diana , Astarita Luca , Parenti Giancarlo , Andria Generoso 
Published: February 2011

AbstractNiemann–Pick disease type C (NPC) is a rare autosomal recessive lysosomal storage disorder characterized by defective intracellular lipid trafficking, with secondary accumulation of free cholesterol, sphingosine, and glycosphingolipids. NPC is clinically characterized by a wide spectrum of manifestations with progressive visceral and neurological involvement, including dysphagia. Neurological manifestations represent the most debilitating findings. Swallowing impairment is a frequent cause of morbidity and disability in NPC patients and progressive dysphagia may be considered a marker of neurological progression. Recently substrate reduction therapy with miglustat has been proposed for the treatment of neurological manifestations in NPC patients. This observational study reports on the long‐term use of miglustat in four pediatric patients with NPC and shows the efficacy of the treatment to improve or prevent dysphagia, and persistence after 3 years of treatment or more. We used a videofluoroscopic analysis of liquid barium swallowing to provide additional information on patterns of impairment of the swallowing mechanism and to detect aspiration. In three patients showing dysphagia and aspiration we observed the improvement of the swallowing function and the sustained absence of barium aspiration in the airways after miglustat treatment, while the patient with normal swallowing function at baseline did not show any deterioration. We suggest that the videofluoroscopic study of swallowing should be routinely used to monitor the effects of treatment on swallowing ability in NPC patients. © 2011 Wiley‐Liss, Inc.
Association of catechol‐O‐methyl transferase (COMT) gene −287A/G polymorphism with susceptibility to obsessive–compulsive disorder in Chinese Han population
Authors: Liu Shiguo , Liu Yanhui , Wang Haiping , Zhou Ruiling , Zong Jinbao , Li Changgui , Zhang Xinhua , Ma Xu 
Published: February 2011

AbstractSeveral studies suggested a genetic component in the etiology of obsessive–compulsive disorder (OCD). COMT involves in the degradation of dopamine and norepinephrin. As another functional SNP locus, COMT −287A/G polymorphism showed an effect on enzyme activity, suggesting that it may influence brain dopamine levels. To identify association of COMT −287A/G polymorphism with susceptibility to OCD in Chinese Han population. We evaluate the genetic contribution of the COMT −287A/G polymorphism in 200 OCD patients and 403 OCD‐free control of Chinese Han population by PCR‐RFLP. In addition, we investigate whether COMT −287A/G polymorphism is associated with one or more of these symptom dimensions or other characteristics such as sex, age of onset, and tic‐relatedness and evaluate the association of the factorial structure of OCD symptoms from the Y‐BOCS checklist with the COMT −287A/G polymorphism. A statistical difference was found in the genotypic frequencies of COMT −287A/G between the OCD and control groups (χ2 = 13.99, DF = 2, P = 0.00091) and in the genotypic frequencies of GG genotype versus AA and AG genotypes of COMT −287 (χ2 = 13.49, DF = 1, P = 0.00024, OR = 3.43, 95% CI = 1.78–6.62). There was a trend for an association in the genotypic distributions of COMT −287A/G polymorphism of males (χ2 = 27.81; DF = 2; P < 0.001) and females (χ2 = 7.31; DF = 2; P = 0.026) between the OCD patients and the controls. Using principal component analysis, we derived 5 factors from 12 main contents of OCD symptoms from the Y‐BOCS checklist and found no association with COMT −287A/G polymorphism. Our study supports the involvement of the COMT −287A/G polymorphism in the genetic susceptibility to OCD in Chinese Han population. © 2011 Wiley‐Liss, Inc.
Effects of anthropogenic disturbance on indri (Indri indri) health in Madagascar
Authors: Junge Randall E. , Barrett Meredith A. , Yoder Anne D. 
Published: February 2011

AbstractAnthropogenic habitat disturbance impairs ecosystem health by fragmenting forested areas, introducing environmental contamination, and reducing the quality of habitat resources. The effect of this disturbance on wildlife health is of particular concern in Madagascar, one of the world's biodiversity hotspots, where anthropogenic pressures on the environment remain high. Despite the conservation importance of threatened lemur populations in Madagascar, few data exist on the effects of anthropogenic disturbance on lemur health. To examine these impacts, indri (Indri indri) populations were evaluated from two forest reserves that differ in their exposure to anthropogenic disturbance. We compared the health status of 36 indri individuals from two sites: one population from a protected, undisturbed area of lowland evergreen humid forest and the other population from a reserve exposed to frequent tourism and forest degradation. Comparison of indri health parameters between sites suggests an impact of anthropogenic disturbance, including significant differences in leukocyte count and differential, 12 serum parameters, 6 trace minerals, and a higher diversity of parasites, with a significant difference in the presence of the louse, Trichophilopterus babakotophilus. These data suggest that indri living in disturbed forests may experience physiological changes and increased susceptibility to parasitism, which may ultimately impair reproductive success and survival. Am. J. Primatol. 73:632–642, 2011. © 2011 Wiley‐Liss, Inc.
Bulk solvent‐free melt ring‐opening polymerization of L‐lactide catalyzed by Cu(II) and Cu(II)–Nd(III) complexes of the Salen‐type Schiff‐base ligand
Authors: Chen Lei‐Lei , Ding Li‐Qin , Zeng Chu , Long Yong , Lü Xing‐Qiang , Song Ji‐Rong , Fan Dai‐Di , Jin Wen‐Juan 
Published: February 2011

AbstractA monometallic (Cu2+, 1) and a bimetallic (Cu2+Nd3+, 2) Salen‐type Schiff‐base complexes with different reactive species, could efficiently catalyze the bulk solvent‐free melt ring‐opening polymerization (ROP) of L‐lactide. Especially for the bimetallic complex 2, the involvement of rare earth ion was important and influential to the catalytic behaviors. Copyright © 2011 John Wiley & Sons, Ltd.
Interaction of aluminoxane particles with weakly charged cationic polyelectrolytes
Authors: Radchenko S. S. , Novakov I. A. , Radchenko Ph. S. , Van Cong Le , Ozerin A. S. , Zel'tser P. S. 
Published: February 2011

AbstractIn terms of the known concepts about noncovalent bonds in polycomplexes, the unusual case of interaction between positively charged aluminoxane particles (AP) ∼ 4.6 nm in size, which comprise the main portion of the dispersed phase in the sols of poly(aluminum hydroxychloride) (PAHC), and weakly charged cationic polyelectrolytes from the Praestol, Organopol, and Zetag series (WCPE) has been examined. Using viscometry, turbidimetry, and elemental analysis, it has been found that interaction between these compounds proceeds if the content of cationic groups in the polyelectrolyte is small and ions of a low‐molecular‐weight electrolyte occur in solution. Under the given conditions, the electrostatic repulsion of likely charged reagents does not manifest itself but other kinds of noncovalent interactions are realized that lead to formation of water‐soluble polymer‐colloid complexes (PCCs). Fully charged polyelectrolytes are incapable of such interactions because of a strong electrostatic repulsion of reagents. The scheme illustrating formation of PCC has advanced. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Influence of cyanate content on the morphology and properties of epoxy resins with phenolphthalein poly(ether ketone)
Authors: Li Junyan , Chen Ping , Yu Qi , Ma Zemin , Ma Keming , Wang Baichen 
Published: February 2011

AbstractPhenolphthalein poly(ether ketone) (PEK‐C) was blended with the diglycidyl ether of bisphenol A epoxy resin and bisphenol A dicyanate ester. The effect of cyanate content on cure behaviors, thermal and mechanical properties of PEK‐C/epoxy/cyanate mixtures was investigated. As results, the increase of cyanate content slightly hindered the cure reaction of the mixtures. Fourier transform infrared results indicated that the curing reaction of the cured mixtures was complete. When the cyanate ester content increased, the flexural properties and Tg values were enhanced, and the initial thermal decomposition temperature was reduced. A significant improvement in fracture toughness was obtained when the cyanate group in the mixtures was excessive. The fracture toughness can be well explained by SEM observations. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Preparation and properties of poly(ethylene terephthalate)/inorganic whiskers composites
Authors: Li Nan , Luo Ping , Liu Kai , Chen Li , Wang Ke , Chen Feng , Fu Qiang 
Published: February 2011

AbstractTo improve the crystallization and mechanical properties of poly(ethylene terephthalate) (PET), in this work, PET/SiO2‐MgO‐CaO whiskers composites were prepared via in situ polymerization. The morphology, crystallization, and mechanical properties of the prepared composites were investigated. It was found that inorganic whiskers could be easily dispersed in PET matrix, as demonstrated by SEM and PLM. DSC and PLM observation indicated a strong nucleation capability of inorganic whiskers for PET. Mechanical analysis results showed that the glass transition temperature, tensile strength, and modulus of the composites were greatly improved. A possible chemical bonding between PET chains and the surface of whiskers was observed by FTIR, TGA, and sedimentation experiment. It could be the main reason for the good dispersion and improved properties of the prepared composites. This work is important for the application of PET due to the low cost but high reinforcing efficiency of this inorganic whisker. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Population assessment and potential functional roles of native mussels in the Upper Mississippi River
Authors: Newton Teresa J. , Zigler Steven J. , Rogala James T. , Gray Brian R. , Davis Mike 
Published: February 2011

Abstract
Despite a heightened global concern for native mussels, fundamental research on mussel ecology in large rivers is lacking. These gaps in knowledge about where mussels occur, and why, are limiting habitat restoration activities.
Large‐scale systematic surveys for native mussels in three reaches of the Upper Mississippi River documented mussel communities composed of 16–23 species and ranging from 2.9–4.5 live mussels m−2 that were actively recruiting new cohorts into their populations (87–100% of the species were found as juveniles ⩽5 years old). Estimates of mean tissue biomass and production in these reaches ranged from 2.1–3.1 g C m−2 and 0.4–0.6 g C m−2 year−1, respectively.
Mussels filtered a significant amount of water (range, 0.05–0.07 m3 m−2 d−1) over a 480 km reach of the Upper Mississippi River – amounting to a filtration rate of 53.1 million m3 day−1. The filtration rate of mussels as a percentage of river discharge ranged from 0.5–1.4% at high flows (5% exceedance), from 1.5–4.4% at moderate flows (50% exceedance) and from 4.4–12.2% during low flows (95% exceedance).
Collectively, these data suggest that native mussels play an integral role in this ecosystem by sequestering suspended materials that can be used by other benthic organisms. Published in 2011 by John Wiley and Sons, Ltd.
Fine mapping of Xq11.1‐q21.33 and mutation screening of RPS6KA6, ZNF711, ACSL4, DLG3, and IL1RAPL2 for autism spectrum disorders (ASD)
Authors: Kantojärvi Katri , Kotala Ilona , Rehnström Karola , Ylisaukko‐oja Tero , Vanhala Raija , von Wendt Taina Nieminen , von Wendt Lennart , Järvelä Irma 
Published: February 2011

AbstractAbout 80% of cases with autism express intellectual disability. Both in autism and in mental retardation without autism the majority of the cases are males, suggesting a X‐chromosomal effect. In fact, some molecular evidence has been obtained for a common genetic background for autism spectrum disorders (ASD) and X‐linked mental retardation (XLMR). In several genome‐wide scans (GWS), evidence for linkage at X‐chromosome has been reported including the GWS of Finnish ASD families with the highest multipoint lod score (MLS) of 2.75 obtained close to DXS7132 at Xq11.1. To further dissect the relationship between autism and genes implicated in XLMR, we have fine‐mapped Xq11.1‐q21.33 and analyzed five candidate genes in the region. We refined the region using 26 microsatellite markers and linkage analysis in 99 Finnish families with ASD. The most significant evidence for linkage was observed at DXS1225 on Xq21.1 with a nonparametric multipoint NPLall value of 3.43 (P = 0.0004). We sequenced the coding regions and splice sites of RPS6KA6 and ZNF711 residing at the peak region in 42 male patients from families contributing to the linkage. We also analyzed ACSL4 and DLG3, which have previously been known to cause XLMR and IL1RAPL2, a homologous gene for IL1RAPL1 that is mutated in autism and XLMR. A total of six novel and 11 known single nucleotide polymorphisms were identified. Further studies are warranted to analyze the candidate genes at Xq11.1‐q21.33. Autism Res 2011,4:228–233. © 2011 International Society for Autism Research, Wiley Periodicals, Inc.
Effects of static magnetic fields on nicotinic cholinergic receptor function
Authors: Tolosa María Fernanda , Bouzat Cecilia , Cravero Walter Rubén 
Published: February 2011

AbstractLigand‐gated ion channel kinetics were studied in mammalian transfected cells encoding adult mouse muscle acetylcholine (ACh) receptors. We measured macroscopic and single‐channel currents using the outside‐out and cell‐attached patch‐clamp configurations. Cultured cells were exposed to moderate intensity inhomogeneous static magnetic fields up to 180 mT and measurements were performed for temperatures ranging from 5 to 50 °C. We found no significant changes in ACh‐elicited macroscopic or single‐channel currents. We observed the expected dependence in current decay constants with temperature, but negligible magnetic field influence on the channel's kinetics. Bioelectromagnetics 32:434–442, 2011. © 2011 Wiley‐Liss, Inc.
Interfacial Electron Transfer Dynamics Following Laser Flash Photolysis of [Ru(bpy)2((4,4′‐PO3H2)2bpy)]2+ in TiO2 Nanoparticle Films in Aqueous Environments
Authors: Brennaman M. Kyle , Patrocinio Antonio Otávio T. , Song Wenjing , Jurss Jonah W. , Concepcion Javier J. , Hoertz Paul G. , Traub Matthew C. , Murakami Iha Neyde Y. , Meyer Thomas J. 
Published: February 2011

AbstractNanosecond laser flash photolysis has been used to investigate injection and back electron transfer from the complex [(Ru(bpy)2(4,4′‐(PO3H2)2bpy)]2+ surface‐bound to TiO2 (TiO2‐RuII). The measurements were conducted under conditions appropriate for water oxidation catalysis by known single‐site water oxidation catalysts. Systematic variations in average lifetimes for back electron transfer, <τbet>, were observed with changes in pH, surface coverage, incident excitation intensity, and applied bias. The results were qualitatively consistent with a model involving rate‐limiting thermal activation of injected electrons from trap sites to the conduction band or shallow trap sites followed by site‐to‐site hopping and interfacial electron transfer, TiO2(e−)‐Ru3+→TiO2‐Ru2+. The appearance of pH‐dependent decreases in the efficiency of formation of TiO2‐Ru3+ and in incident‐photon‐to‐current efficiencies with the added reductive scavenger hydroquinone point to pH‐dependent back electron transfer processes on both the sub‐nanosecond and millisecond–microsecond time scales, which could be significant in limiting long‐term storage of multiple redox equivalents.
Electrocatalytic Carbon Dioxide Activation: The Rate‐Determining Step of Pyridinium‐Catalyzed CO2 Reduction
Authors: Morris Amanda J. , McGibbon Robert T. , Bocarsly Andrew B. 
Published: February 2011

AbstractThe reactivity of reduced pyridinium with CO2 was investigated as a function of catalyst concentration, temperature, and pressure at platinum electrodes. Concentration experiments show that the catalytic current measured by cyclic voltammetry increases linearly with pyridinium and CO2 concentrations; this indicates that the rate‐determining step is first order in both. The formation of a carbamate intermediate is supported by the data presented. Increased electron density at the pyridyl nitrogen upon reduction, as calculated by DFT, favors a Lewis acid/base interaction between the nitrogen and the CO2. The rate of the known side reaction, pyridinium coupling to form hydrogen, does not vary over the temperature range investigated and had a rate constant of 2.5 M−1 s−1. CO2 reduction followed Arrhenius behavior and the activation energy determined by electrochemical simulation was (69±10) kJ mol−1.
Integrating multimedia streaming from heterogeneous sources to JavaME mobile devices
Authors: Calvo‐Flores M. Delgado , Quero J. Medina , Lozano M. D. Ruiz , Miranda A. Vila 
Published: February 2011

SUMMARYThanks to technological advancement, at present there exist many devices with multimedia support in our environment; among them, being mobile devices, which offer the ability to display video and audio resources from the palm of the hands, and even act as multimedia sources. However, the heterogeneity of such devices makes the multimedia integration difficult to get portable solutions. This problem is the focus of this document, which integrates environmental multimedia resources (IP cameras, Webcams, Aibo cameras and microphones) to be played in real time over Virtual Machines, in particular, using JavaME devices. We also present the techniques for generating multimedia streaming from the Virtual Machines accessing the cameras and microphones of mobile devices. Copyright © 2011 John Wiley & Sons, Ltd.