bluuebunny/crossref_metadata_2025_split huggingface dataset:
Favorable outcome of allogeneic hematopoietic cell transplantation for 8p11 myeloproliferative syndrome associated with BCR‐FGFR1 gene fusion
Authors: Dolan Michelle , Cioc Adina , Cross Nicholas C.P. , Neglia Joseph P. , Tolar Jakub 
Published: November 2011

AbstractWe report the case of a child who presented with nonspecific symptoms suggestive of a rheumatologic disorder, whose bone marrow had a complex translocation involving the FGFR1 locus. Hematopathologic findings were subtle and did not definitively indicate malignancy. Because he responded poorly to initial treatment with hydroxyurea, and in light of the progressive clinical course associated with the 8p11 myeloproliferative syndrome, he underwent an unrelated‐donor hematopoietic stem cell transplant. This patient's atypical presentation highlights the importance of obtaining cytogenetic analysis at the time of bone marrow sampling and considering this uncommon entity in the differential diagnosis of hematologic disorders. Pediatr Blood Cancer 2012; 59: 194–196. © 2011 Wiley Periodicals, Inc.
LC‐UV Assay Method and UPLC/Q‐TOF‐MS Characterisation of Saponins from Ilex Paraguariensis A. St. Hil. (Mate) Unripe Fruits
Authors: Peixoto Maria Paula Garofo , Kaiser Samuel , Verza Simone Gasparin , de Resende Pedro Ernesto , Treter Janine , Pavei Cabral , Borré Gustavo Luís , Ortega George González 
Published: November 2011

ABSTRACTIntroductionIlex paraguariensis A. St. Hil. (mate) is known in several South American countries because of the use of its leaves in stimulant herbal beverages. High saponin contents were reported in mate leaves and unripe fruits that possess a dissimilar composition. Two LC‐UV methods previously reported for mate saponins assay focused on mate leaves and the quantification of the less polar saponin fraction in mate fruits.ObjectiveTo develop and validate a LC‐UV method to assay the total content of saponins in unripe mate fruits and characterise the chemical structure of triterpenic saponins by UPLC/Q‐TOF‐MS.MethodologyFrom unripe fruits of mate a crude ethanolic extract was prepared (EX40) and the mate saponin fraction (MSF) purified by solid phase extraction. The LC‐UV method was validated using ilexoside II as external standard. UPLC/Q‐TOF‐MS was adjusted from the LC‐UV method to obtain the fragmentation patterns of the main saponins present in unripe fruits.ResultsBoth LC‐UV and UPLC/Q‐TOF‐MS methods indicate a wide range of Ilex saponins polarity. The ilexoside II and total saponin content of EX40 were 8.20% (w/w) and 47.60% (w/w), respectively. The total saponin content in unripe fruits was 7.28% (w/w). The saponins present in MSF characterised by UPLC/Q‐TOF‐MS are derived mainly from ursolic/oleanolic, acetyl ursolic or pomolic acid.ConclusionThe validated LC‐UV method was shown to be linear, precise, accurate and to cover several saponins previously isolated from Ilex species and could be applied for the quality control of unripe fruit saponins. Copyright © 2011 John Wiley & Sons, Ltd.
Analytical study and evaluation results of power optimizers for distributed power conditioning in photovoltaic arrays
Authors: Orduz Ricardo , Solórzano Jorge , Egido Miguel Ángel , Román Eduardo 
Published: November 2011

ABSTRACTThe use of modular or ‘micro’ maximum power point tracking (MPPT) converters at module level in series association, commercially known as “power optimizers”, allows the individual adaptation of each panel to the load, solving part of the problems related to partial shadows and different tilt and/or orientation angles of the photovoltaic (PV) modules. This is particularly relevant in building integrated PV systems. This paper presents useful behavioural analytical studies of cascade MPPT converters and evaluation test results of a prototype developed under a Spanish national research project. On the one hand, this work focuses on the development of new useful expressions which can be used to identify the behaviour of individual MPPT converters applied to each module and connected in series, in a typical grid‐connected PV system. On the other hand, a novel characterization method of MPPT converters is developed, and experimental results of the prototype are obtained: when individual partial shading is applied, and they are connected in a typical grid connected PV array. Copyright © 2011 John Wiley & Sons, Ltd.
Synthesis of fluorene‐based hyperbranched polymers for solution‐processable blue, green, red, and white light‐emitting devices
Authors: Shih Hung‐Min , Wu Ren‐Chi , Shih Ping‐I , Wang Chien‐Lung , Hsu Chain‐Shu 
Published: November 2011

AbstractFor the purpose of making hyperbranched polymer (Hb‐Ps)‐based red, green, blue, and white polymer light‐emitting diodes (PLEDs), three Hb‐Ps Hb‐terfluorene (Hb‐TF), Hb‐4,7‐bis(9,9′‐dioctylfluoren‐2‐yl)‐2,1,3‐benzothiodiazole (Hb‐BFBT), and Hb‐4,7‐bis[(9,9′‐dioctylfluoren‐2‐yl)‐thien‐2‐yl]‐2,1,3‐benzothiodiazole (Hb‐BFTBT) were synthesized via [2+2+2] polycyclotrimerization of the corresponding diacetylene‐functionalized monomers. All the synthesized polymers showed excellent thermal stability with degradation temperature higher than 355 °C and glass transition temperatures higher than 50 °C. Photoluminance (PL) and electroluminance (EL) spectra of the polymers indicate that Hb‐TF, Hb‐BFBT, and Hb‐BFTBT are blue‐green, green, and red emitting materials. Maximum brightness of the double‐layer devices of Hb‐TF, Hb‐BFBT, and Hb‐BFTBT with the device configuration of indium tin oxide/poly(3,4‐ethylene dioxythiophene):poly(styrene sulfonate)/light‐emitting polymer/CsF/Al are 48, 42, and 29 cd/m2; the maximum luminance efficiency of the devices are 0.01, 0.02, and 0.01 cd/A. By using host–guest doped system, saturated red electrophosphorescent devices with a maximum luminance efficiency of 1.61 cd/A were obtained when Hb‐TF was used as a host material doped with Os(fptz)2(PPh2Me2)2 as a guest material. A maximum luminance efficiency of 3.39 cd/A of a red polymer light‐emitting device was also reached when Hb‐BFTBT was used as the guest in the PFO (Poly(9,9‐dioctylfluorene)) host layer. In addition, a series of efficient white devices were, which show low turn‐on voltage (3.5 V) with highest luminance efficiency of 4.98 cd/A, maximum brightness of 1185 cd/m2, and the Commission Internationale de l'Eclairage (CIE) coordinates close to ideal white emission (0.33, 0.33), were prepared by using BFBT as auxiliary dopant. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
The effect of ammonia flow in the AlN spacer on the electrical properties of InAlN/AlN/GaN HEMT structures
Authors: Gamarra Piero , Lacam Cedric , Magis Michelle , Tordjman Maurice , Poisson Marie‐Antoinette di Forte 
Published: November 2011

AbstractDuring the past few years it has been reported that a thin AlN spacer of few nanometers needs to be inserted in InAlN/GaN high electron mobility transistors (HEMTs) to obtain high 2DEG carrier mobility. This work presents a systematic study of the effects of varying the ammonia flow in the AlN spacer of InAlN/AlN/GaN HEMTs grown by low pressure metalorganic vapour phase epitaxy (LP‐MOVPE). The strain state, the surface roughness and the growth rate of AlN were found to be dependent on the V/III ratio. In addition the ammonia flow in the interlayer has a strong impact on the structural properties of the subsequent InAlN barrier layer and on the electrical properties of the structure. A sheet resistance as low as 327 Ω/□ with a sheet carrier density of 1.5 × 1013 cm−2 has been obtained at room temperature.
Electric characteristics of ruthenium doped InP and its application for buried‐heterostructure lasers
Authors: Yamaguchi Harunaka , Nagira Takashi , Sakaino Go , Ono Kenichi , Takemi Masayoshi 
Published: November 2011

AbstractIn recent years, ruthenium (Ru) has been focused on the new semi‐insulated doping material for InP instead of Fe. Semi‐insulated InP is essential for the blocking layer of high modulation speed laser diode in terms of the capacitance and heat dissipation. In this paper, we have investigated the electric characteristic of Ru doped InP (Ru‐InP) which works both electron and hole trap characteristics. We fabricated n‐InP/Ru‐InP/n‐InP (n/Ru/n‐InP) and p‐InP/Ru‐InP/p‐InP (p/Ru/p‐InP) structure by Metal Organic Vapor Phase Epitaxy (MOVPE), and evaluated I‐V characteristics of its structure. It turned out from this experiment that the volume resistivity of p/Ru/p‐InP structure was higher than that of n/Ru/n‐InP. The resistivity of p/Ru/p‐InP was almost equal to that of n/Fe/n‐InP. We applied the Ru‐InP to the Buried‐Heterostructure DFB Laser as current blocking layer. We confirmed that the temperature dependence of LD characteristics was improved, and the output power was over 10mW even at 70 °C (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
InGaN photodiodes using CaF2 insulator for high‐temperature UV detection
Authors: Sang L. W. , Liao M. Y. , Koide Y. , Sumiya M. 
Published: November 2011

AbstractThe authors report on a thermally‐stable ultraviolet‐A photodiode using CaF2 as the insulation layer in the metal‐insulator‐semiconductor (MIS) structure based on a high‐quality InGaN film. Compared to the Schottky photodiode (SPD) without the insulator, the MIS‐SPD device maintains a low reverse leakage current, a high photo‐to‐dark current ratio and fast response at the temperature as high as 523 K, indicating CaF2 as a good candidate for the III‐Nitride devices. The overall photoresponse properties of the MIS‐SPD are governed by the metal/insulator/semiconductor interfaces. The photocurrent gain at reverse biases from room‐temperature to 463 K is interpreted in term of thermionic‐field emission (TFE) and field emission mechanism, while TFE becomes the dominant mechanism at higher temperatures (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Effect of GaN cap thickness on carrier dynamics in InGaN quantum wells
Authors: Kopylov O. , Shirazi R. , Svensk O. , Suihkonen S. , Sintonen S. , Sopanen M. , Kardynał B. E. 
Published: November 2011

AbstractWe have studied optical properties of single In0.1Ga0.9N quantum wells with GaN barriers in close proximity to the wafer surface (<10 nm). We have found that at room temperature a balance of radiative, non‐radiative recombination and complex surface states effects results in an optimum cap thickness of 3nm for achieving highest brightness emitters. At low temperature, we observe a behaviour that suggests that some surface states act as trapping centres for carriers rather than as a non‐radiative recombination channel. Temperature dependence of the photoluminescence decay curves shows that carrier lifetimes in all the wafers increase at lower temperatures and reach similar maximum value. Main features of the evolution of lifetimes with temperature can be explained satisfactory by a combination of radiative, non‐radiative recombination and above mentioned twofold surface effects. Detailed picture of the carrier dynamics is however complex and needs to include the modification of the electrostatic potential in the quantum wells positioned in the surface depletion regions (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
X‐ray excited optical luminescence imaging of InGaN nano‐LEDs
Authors: Martínez‐Criado G. , Sans J. A. , Segura‐Ruiz J. , Tucoulou R. , Solé A. V. , Homs A. , Yoo J. , Yi J. G.‐C. , Alén B. 
Published: November 2011

AbstractIn this work, an imaging tool to investigate optical inhomogeneities with site and chemical sensitivities has been integrated in a synchrotron radiation nanoprobe. Coaxial GaN/In1–xGaxN/GaN/ZnO nanoarchitecture light emitting diode (LED) arrays are used to validate the scanning x‐ray excited luminescence technique. Elemental maps and luminescence images of the hexagonal InGaN multiple quantum wells and inner deposited layers are reported with 120 nm spatial resolution. Within the experimental accuracy, the X‐ray fluorescence results reveal an homogeneous distribution of the major elements involved in the pattern formation and heteroepitaxial nanotube growth. In comparison to the morphological pattern, the optical emissions from individual nanowires exhibit a striking spatial variation, indicating significant changes in the quantum confinement effects. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Ab initio electron energy‐loss spectra and depolarization effects: Application to carbon nanotubes
Authors: Amzallag E. , Ehinon D. , Martinez H. , Rérat M. , Baraille I. 
Published: November 2011

AbstractWe perform ab initio calculations of the optical absorption and electron energy‐loss spectra of (m, 0) single‐walled carbon nanotubes (with m ≠ 3n for m = 7‐25) in the framework of a “sum over states” (SOS) treatment of the Kohn‐Sham (KS) single‐particle orbitals and energies (CRYSTAL program). This approach tested on hexagonal boron nitride enables to fully assign the interband transitions in the imaginary part of the dielectric constant, in terms of atomic orbitals. As these calculations could not take into account the local field effects (depolarization effects), which take place for perpendicular polarizations in 2D and 1D periodic systems, we apply a simple method based on the Clausius‐Mossotti formula, relating the SOS and coupled‐perturbed KS polarizability values. This approach reproduces the main features of the spectra of boron nitride (001) surface and carbon nanotubes. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2012
Ferroelectric Thin Films in Fluidic Environments: A New Interface for Sensing and Manipulation of Matter
Authors: Ferris Robert , Yellen Benjamin , Zauscher Stefan 
Published: November 2011

AbstractFor decades ferroelectric thin films (FETFs) have been the focus of research and development for next‐generation memory and semiconductor devices. FETFs are attractive because their polarization states are highly localized, stable, and switchable. These unique properties are also attractive for (bio)molecular sensing and separation applications. Polarization of both polymer and ceramic FETF results in the expression of a sustained high, non‐Faradaic, surface charge density. If these surface charges are maintained in aqueous environments, then the resulting electrostatic forces should induce the formation of electrolyte gradients and aid in the localization of charged species to the surface. Recently, there has been a growing interest in the interfacial properties of FETFs, specifically how they interact with liquid or gaseous phases. Recent work has shown that the FETF polarization state affects adsorption from the gaseous phase, surface catalysis, and cell growth. Encouraged by these findings, the use of FETFs in aqueous environments is explored. After an introduction to FETFs, the growing body of literature on the FETF interface is reviewed, along with the limited number of studies demonstrating FETF function in gas and liquid environments. Finally, the exciting possibilities that FETFs could bring to interfacial engineering and lab‐on‐chip (LOC) device design is reviewed.
Neurodevelopmental outcome of fetuses with increased nuchal translucency and apparently normal prenatal and/or postnatal assessment: a systematic review
Authors: Sotiriadis A. , Papatheodorou S. , Makrydimas G. 
Published: November 2011

AbstractObjectivesTo systematically review and, when feasible, pool, published data regarding the prevalence of childhood neurodevelopmental delay in fetuses with increased first‐trimester nuchal translucency (NT), normal karyotype and absence of structural defects or identifiable syndromes.MethodsMEDLINE and SCOPUS searches using combinations of the terms ‘nuchal translucency’ AND ‘outcome*’ were complemented by perusal of the references of the retrieved articles and an additional automated search using the ‘search for related articles’ PubMed function. Only children with a normal karyotype and no structural defects or syndromic abnormalities were included in the analysis. Between‐studies heterogeneity was assessed using the I2 statistic.ResultsThe total prevalence of developmental delay in all 17 studies was 28/2458 (1.14%; 95% CI, 0.79–1.64; I2 = 57.6%). Eight studies (n = 1567) used NT > 99th centile as the cut‐off; 15 children (0.96%; 95% CI, 0.58–1.58%) were reported as having developmental delay (I2 = 72.2%). Four studies (n = 669) used the 95th centile as the cut‐off for increased NT; seven children (1.05%; 95% CI, 0.51–4.88%) were reported as having developmental delay (I2 = 29.2%). Five studies used 3.0 mm as the cut‐off for increased NT; the pooled rate of developmental delay was six of 222 children (2.70%; 95% CI, 1.24–5.77%; I2 = 0.0%).ConclusionThe rate of neurodevelopmental delay in children with increased fetal NT, a normal karyotype, normal anatomy and no identifiable genetic syndromes does not appear to be higher than that reported for the general population. More large‐scale, prospective case–control studies would be needed to enhance the robustness of the results. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
Biometry and fetal weight estimation by two‐dimensional and three‐dimensional ultrasonography: an intraobserver and interobserver reliability and agreement study
Authors: Lima J. C. , Miyague A. H. , Filho F. M. , Nastri C. O. , Martins W. P. 
Published: November 2011

AbstractObjectiveTo evaluate and compare the intraobserver and interobserver reliability and agreement for the biparietal diameter (BPD), abdominal circumference (AC), femur length (FL) and estimated fetal weight (EFW) obtained by two‐dimensional ultrasound (2D‐US) and three‐dimensional ultrasound (3D‐US).MethodsSingleton pregnant women between 24 and 40 weeks were invited to participate in this study. They were examined using 2D‐US in a blinded manner, twice by one observer, intercalated by a scan by a second observer, to determine BPD, AC and FL. In each of the three examinations, three 3D‐US datasets (head, abdomen and thigh) were acquired for measurements of the same parameters. We determined EFW using Hadlock's formula. Systematic errors between 3D‐US and 2D‐US were examined using the paired t‐test. Reliability and agreement were assessed by intraclass correlation coefficients (ICCs), limits of agreement (LoA), SD of differences and proportion of differences below arbitrary points.ResultsWe evaluated 102 singleton pregnancies. No significant systematic error between 2D‐US and 3D‐US was observed. The ICC values were higher for 3D‐US in both intra‐ and interobserver evaluations; however, only for FL was there no overlap in the 95% CI. The LoA values were wider for 2D‐US, suggesting that random errors were smaller when using 3D‐US. Additionally, we observed that the SD values determined from 3D‐US differences were smaller than those obtained for 2D‐US. Higher proportions of differences were below the arbitrarily defined cut‐off points when using 3D‐US.Conclusion3D‐US improved the reliability and agreement of fetal measurements and EFW compared with 2D‐US. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.
Predictive value of sequential models of uterine artery Doppler in pregnancies at high risk for pre‐eclampsia
Authors: Herraiz I. , Escribano D. , Gómez‐Arriaga P. I. , Herníndez‐García J. M. , Herraiz M. A. , Galindo A. 
Published: November 2011

AbstractObjectiveTo evaluate the performance of models described previously for the prediction of pre‐eclampsia (PE), based on the sequential evaluation of uterine artery resistance at 11–13 weeks and 19–22 weeks, in a high‐risk population.MethodsThis was a prospective study in 135 women with singleton pregnancies and at least one of the following high‐risk conditions: PE and/or intrauterine growth restriction in a previous pregnancy, chronic hypertension, pregestational diabetes, renal disease, body mass index > 30 kg/m2, autoimmune disease (systemic lupus erythematosus, antiphospholipid syndrome or rheumatoid arthritis) and thrombophilia. Mean uterine artery pulsatility index (mUtA‐PI) at 11–13 and at 19–22 weeks' gestation was measured and analyzed according to quantitative and semi‐quantitative models, to predict late PE (resulting in delivery ≥ 34 weeks) and early PE (delivery < 34 weeks).ResultsLate PE developed in 21 (15.6%) pregnancies and early PE in six (4.4%). Using mUtA‐PI, the detection rates of late and early PE for a false‐positive rate of 10% were 14.3% and 33.3%, respectively, at 11–13 weeks, and 19.0% and 66.7%, respectively, at 19–22 weeks. Using a semi‐quantitative approach, the group of pregnant women with mUtA‐PI ≥ 90th percentile at both 11–13 and 19–22 weeks had a greater risk for early PE (odds ratio, 21.4 (95% CI, 2.5–184.7)) compared with the group with mUtA‐PI < 90th percentile at both periods. Using a quantitative approach, there was relative worsening in the mUtA‐PI (multiples of the median) from the first to the second trimester in all cases of early PE.ConclusionThe application of semi‐quantitative and especially quantitative models to evaluate sequential changes in uterine artery Doppler findings between the first and second trimesters could be of additional value in assessing high‐risk women regarding their true risk of developing early PE. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.
INDICO: the development of a resource for epigenomic study of Indians undergoing socioeconomic transition
Authors:   INdian DIabetes COnsortium
Published: November 2011

Abstract
The INdian DIabetes COnsortium (INDICO) is an initiative to build a resource for genetic, epigenetic and clinical studies of type 2 diabetes (T2D) in socioeconomically transiting Indians. The consortium aims to follow selected communities which are undergoing rapid urbanization over a period of years to create a knowledge base for the better understanding of the gene-environment interaction in T2D. These resources can eventually be of value to not just the diabetes research community but would be able to contribute towards an improved understanding, diagnosis and prevention of numerous complex human disorders.
Determining what sets of trees can be the clique trees of a chordal graph
Authors: De Caria Pablo , Gutierrez Marisa 
Published: November 2011

Abstract
Chordal graphs have characteristic tree representations, the clique trees. The problems of finding one or enumerating them have already been solved in a satisfactory way. In this paper, the following related problem is studied: given a family "Equation missing" of trees, all having the same vertex set V, determine whether there exists a chordal graph whose set of clique trees equals "Equation missing". For that purpose, we undertake a study of the structural properties, some already known and some new, of the clique trees of a chordal graph and the characteristics of the sets that induce subtrees of every clique tree. Some necessary and sufficient conditions and examples of how they can be applied are found, eventually establishing that a positive or negative answer to the problem can be obtained in polynomial time. If affirmative, a graph whose set of clique trees equals "Equation missing" is also obtained. Finally, all the chordal graphs with set of clique trees equal to "Equation missing" are characterized.