bluuebunny/crossref_metadata_2025_split huggingface dataset:
Change in waist circumference over 11 years and current waist circumference independently predict elevated CRP in Filipino women
Authors: Rutherford Julienne N. , Mcdade Thomas W. , Lee Nanette R. , Adair Linda S. , Kuzawa Christopherw 
Published: October 2009

AbstractC‐reactive protein, a marker of chronic, low‐grade inflammation, is strongly associated with current central adiposity, and has been linked to elevated risk of cardiovascular disease. Less is known about the contribution of longitudinal change in waist circumference to current inflammation. We evaluated the extent to which current waist circumference and change over an 11‐year interval contribute independently to low‐grade systemic inflammation measured in a group of 1,294 women, 35–69 years, participating in the Cebu Longitudinal Nutrition and Health Survey in the Philippines. Waist circumference was measured at the time of blood draw for CRP analysis in 2005 and during an earlier survey in 1994. A waist circumference delta variable was constructed by subtracting current circumference from past circumference. We used logistic regression models to predict having an elevated plasma CRP concentration (3 mg L−1 < CRP < 10 mg L−1). Waist circumference in 2005 was a strong predictor of elevated CRP (OR 1.10, 95% CI = 1.08, 1.12, P < 0.001). In combined models, increase in circumference over 11 years was a significant and independent predictor of elevated CRP risk (OR = 1.023, 95% CI = 1.00, 1.05, P < 0.05). Considering the average increase over time, the cumulative risk of elevated CRP due to increased central adiposity was 25.7%. However, women who reduced their waist circumference between 1994 and 2005 had greatly reduced risk (6.2%), suggesting that even long‐term inflammatory burden can be reversed by weight loss. Although current waist circumference is an important contributor to risk of elevated systemic inflammation in this as in other populations, history of central adiposity may be an independent phenomenon. Am. J. Hum. Biol. 2010. © 2009 Wiley‐Liss, Inc.
Occupational obstructive airway diseases caused by the natural gas odorant tetrahydrothiophene—two case reports
Authors: Baur X. , Bittner C. 
Published: October 2009

AbstractBackgroundTetrahydrothiophene (THT) is frequently used to odorize natural (city) gas. Only sparse data on adverse health effects of THT on humans are available.MethodsWe performed a literature search and clinical investigations including case history and cardiopulmonary diagnostic tests in two symptomatic THT‐exposed outpatients.ResultsThe two THT‐exposed city workers developed transient neurologic symptoms such as nausea, vomiting, headaches, as well as skin and mucosa irritation, chronic rhinitis, chronic obstructive pulmonary disease, arterial hypertension, and cardiac arrhythmia. The neurological symptoms and respiratory disorders were found to be caused by intermittently high THT exposures. In favor of a causal relationship were severe work‐related neurological and respiratory symptoms in previously healthy workers, results of animal experiments, and another report with very similar findings in the literature. The etiology of arterial hypertension and cardiac arrhythmia, however, remains unclear.ConclusionsOur two case reports demonstrate that repeated high THT‐exposures can—in addition to neurotoxic symptoms—elicit chronic obstructive pulmonary disease. We recommend improved primary and secondary preventive measures, including the establishment of a TLV. Am. J. Ind. Med. 52:982–986, 2009. © 2009 Wiley‐Liss, Inc.
Occupational injuries among aides and nurses in acute care
Authors: Rodríguez‐Acosta R.L. , Richardson D.B. , Lipscomb H.J. , Chen J.C. , Dement J.M. , Myers D.J. , Loomis D.P. 
Published: October 2009

AbstractBackgroundOccupational injuries are common among nursing personnel. Most epidemiologic research on nursing aides comes from long‐term care settings. Reports from acute care settings often combine data on nurses and aides even though their job requirements and personal characteristics are quite different. Our objective was to assess risk of work‐related injuries in an acute care setting while contrasting injuries of aides and nurses.MethodsA retrospective cohort of aides (n = 1,689) and nurses (n = 5,082) working in acute care at a large healthcare system between 1997 and 2004 were identified via personnel records. Workers' compensation filings were used to ascertain occupational injuries. Poisson regression was used to estimate rate ratios (RR) and 95% confidence intervals (95% CI).ResultsAides had higher overall injury rates than nurses for no‐lost work time (RR = 1.2, 95% CI: 1.1–1.3) and lost work time (RR = 2.8, 95% CI: 2.1–3.8) injuries. The risk of an injury due to lifting was greater among aides compared to nurses for both non‐lost work time and lost work time injuries. Injury rates among aides were particularly high in rehabilitation and orthopedics units. Most of the injuries requiring time away from work for both groups were related to the process of delivering direct patient care.ConclusionsOur findings illustrate the importance of evaluating work‐related injuries separately for aides and nurses, given differences in injury risk profiles and injury outcomes. It is particularly important that occupational safety needs of aides be addressed as this occupation experiences significant job growth. Am. J. Ind. Med. 52:953–964, 2009. © 2009 Wiley‐Liss, Inc.
Synthesis and Evaluation on Anticonvulsant and Antidepressant Activities of 5‐Alkoxy‐tetrazolo[1,5‐a]quinazolines
Authors: Wang Huo‐Jian , Wei Cheng‐Xi , Deng Xian‐Qing , Li Fu‐Lan , Quan Zhe‐Shan 
Published: October 2009

AbstractSeveral 5‐alkoxy‐tetrazolo[1,5‐a]quinazoline derivatives have been synthesized by reacting 2,4‐dichloroquinazoline with various phenols or aliphatic alcohol and then with sodium azide. The structures of these compounds have been confirmed by IR, MS, 1H‐NMR, and elementary analysis. Anticonvulsant activities were evaluated using the maximal electroshock (MES) test. Most of the synthesized compounds displayed weak anticonvulsant activity at a dose of 300 mg/kg. Antidepressant activities were investigated by forced swimming test. Two compounds, namely 5‐(hexyloxy)tetrazolo[1,5‐a]quinazoline and 5‐(4‐methoxyphenoxy)tetrazolo[1,5‐a]quinazoline, showed significant antidepressant activity, which decreased the immobility time by 62.2 and 51.7% at 100 mg/kg dose level.
Proline Analogue of Nitrosourea as a New Cytotoxic Prodrug
Authors: Stankiewicz‐Kranc Anna , Bielawska Anna , Bielawski Krzysztof , Skrzydlewska Elzbieta 
Published: October 2009

AbstractCarmustine is frequently used as anticancer drug. High toxicity and low selectivity reduces the application of this drug. Though, there is a necessity to find new compounds characterized by similar therapeutic effects but a higher selectivity and safety. As a result, the proline analogue of nitrosourea, N‐[N′‐(2‐bromophenyl)‐N′‐nitrosocarbamoyl]proline (AC), has been synthesized. The aim of this study was to compare the influence of carmustine and the proline analogue of nitrosourea on the antioxidant abilities of fibroblasts and leukemia cells, MOLT4. It was shown that carmustine as well as AC cause an increase in hydrogen peroxide concentration in normal and neoplastic cells. Incubation with both compounds led to a diminution of the activity of antioxidant enzymes such as superoxide dismutase, glutathione peroxidase, and reductase. Changes in activity / level of antioxidant parameters were accompanied by augmentation of lipid and oxidative protein modifications. In conclusion, carmustine and AC cause changes in the antioxidative system of normal and MOLT4 cells and are a reason of oxidative stress formation.
Fed‐batch production of tetanus toxin by Clostridium tetani
Authors: Fratelli Fernando , Siquini Tatiana Joly , de Abreu Marcelo Estima , Higashi Hisako Gondo , Converti Attilio , de Carvalho João Carlos Monteiro 
Published: October 2009

AbstractThis study deals with the effects of the initial nitrogen source (NZ Case TT) level and the protocol of glucose addition during the fed‐batch production of tetanus toxin by Clostridium tetani. An increase in the initial concentration of NZ Case TT (NZ0) accelerated cell growth, increased the consumption of the nitrogen source as well as the final yield of tetanus toxin, which achieved the highest values (50–60 Lf/mL) for NZ0 ≥ 50 g/L. The addition of glucose at fixed times (16, 56, and 88 h) ensured a toxin yield (∼60 Lf/mL) about 33% higher than those of fed‐batch runs with addition at fixed concentration (∼45 Lf/mL) and about 300% higher than those obtained in reference batch runs nowadays used at industrial scale. The results of this work promise to substantially improve the present production of tetanus toxin and may be adopted for human vaccine production after detoxification and purification. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2010
Carbon nanotube clusters as universal bacterial adsorbents and magnetic separation agents
Authors: Moon Hyung‐Mo , Kim Jin‐Woo 
Published: October 2009

AbstractThe magnetic susceptibility and high bacterial affinity of carbon nanotube (CNT) clusters highlight their great potential as a magnetic bio‐separation agent. This article reports the CNT clusters' capability as “universal” bacterial adsorbents and magnetic separation agents by designing and testing a multiwalled carbon nanotube (MWNT) cluster‐based process for bacterial capturing and separation. The reaction system consisted of large clusters of MWNTs for bacterial capture and an external magnet for bio‐separation. The designed system was tested and optimized using Escherichia coli as a model bacterium, and further generalized by testing the process with other representative strains of both gram‐positive and gram‐negative bacteria. For all strains tested, bacterial adsorption to MWNT clusters occurred spontaneously, and the estimated MWNT clusters' adsorption capacities were nearly the same regardless of the types of strains. The bacteria‐bound MWNT clusters also responded almost instantaneously to the magnetic field by a rare‐earth magnet (0.68 Tesla), and completely separated from the bulk aqueous phase and retained in the system. The results clearly demonstrate their excellent potential as highly effective “universal” bacterial adsorbents for the spontaneous adsorption of any types of bacteria to the clusters and as paramagnetic complexes for the rapid and highly effective magnetic separations. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2010
Inhibition of HSP90 with Pochoximes: SAR and Structure‐Based Insights
Authors: Barluenga Sofia , Fontaine Jean‐Gonzague , Wang Cuihua , Aouadi Kais , Chen Ruihong , Beebe Kristin , Neckers Len , Winssinger Nicolas 
Published: October 2009

AbstractThe pochoximes, based on the radicicol pharmacophore, are potent inhibitors of heat shock protein 90 (HSP90) that retain their activity in vivo. Herein we report an extended library that broadly explores the structure–activity relationship (SAR) of the pochoximes with four points of diversity. Several modifications were identified that afford improved cellular efficacy, new opportunities for conjugation, and further diversifications. Cocrystal structures of pochoximes A and B with HSP90 show that pochoximes bind to a different conformation of HSP90 than radicicol and provide a rationale for the enhanced affinity of the pochoximes relative to radicicol and the pochonins.
Molecular Double‐Bond Covalent Radii for Elements Li–E112
Authors: Pyykkö Pekka , Atsumi Michiko 
Published: October 2009

AbstractThe previous systems of triple‐bond and single‐bond self‐consistent, additive covalent radii, R(AB)=r(A)+ r(B), are completed with a fit for σ2π2 double‐bonds.The primary bond lengths, R, are taken from experimental or theoretical data corresponding to chosen group valencies. All r(E) values are obtained from the same, self‐consistent fit. Many of the calculated primary data came from ECH2 and HECH2 models. Homonuclear LEEL, formaldehyde‐type Group 14–Group 16 and open‐shell, X 3 Σ Group‐16 dimer data are included. The standard deviation for the 316 included data points is 3 pm.
Double Group Transfer Reactions: Role of Activation Strain and Aromaticity in Reaction Barriers
Authors: Fernández Israel , Bickelhaupt F. Matthias , Cossío Fernando P. 
Published: October 2009

AbstractDouble group transfer (DGT) reactions, such as the bimolecular automerization of ethane plus ethene, are known to have high reaction barriers despite the fact that their cyclic transition states have a pronounced in‐plane aromatic character, as indicated by NMR spectroscopic parameters. To arrive at a way of understanding this somewhat paradoxical and incompletely understood phenomenon of high‐energy aromatic transition states, we have explored six archetypal DGT reactions using density functional theory (DFT) at the OLYP/TZ2P level. The main trends in reactivity are rationalized using the activation strain model of chemical reactivity. In this model, the shape of the reaction profile ΔE(ζ) and the height of the overall reaction barrier ΔE≠=ΔE(ζ=ζTS) is interpreted in terms of the strain energy ΔEstrain(ζ) associated with deforming the reactants along the reaction coordinateζplus the interaction energy ΔEint(ζ) between these deformed reactants: ΔE(ζ)=ΔEstrain(ζ)+ΔEint(ζ). We also use an alternative fragmentation and a valence bond model for analyzing the character of the transition states.
ChemInform Abstract: Phase Transition of Rubidium Lead Tetrathiophosphate RbPbPS4.
Authors: Belkyal Imane , El Azhari Mohamed , Wu Yuandong , Bensch Wolfgang , Depmeier Wulf 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Investigation on Double Perovskite Ba4Ca2Ta2O11.
Authors: Baliteau S. , Mauvy F. , Fourcade S. , Grenier J. C. 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Quaternary Tin(V) Antimony(III) Sulfide Decorated with Lanthanum(III) Ethylenediamine Complexes: [La(en)4SbSnS5]2·0.5H2O.
Authors: Feng Mei‐Ling , Ye Dong , Huang Xiao‐Ying 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Room‐Temperature Ru(II)‐Catalyzed Transfer Hydrogenation of Ketones and Aldehydes in Air.
Authors: Zhao Miao , Yu Zhengkun , Yan Shenggang , Li Yang 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Chemoselective Addition of Grignard Reagents to Carbonyl Compounds in 2‐Methyltetrahydrofuran.
Authors: Zhong Weihui , Wu Yaotiao , Zhang Xingxian 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild Hydrodehalogenation of Fluoroalkyl Halides.
Authors: Zhang Cheng‐Pan , Chen Qing‐Yun , Xiao Ji‐Chang , Gu Yu‐Cheng 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: O‐Arylsulfonyl Hydroxylamines via a Decarboxylative Rearrangement.
Authors: Fioravanti Stefania , Pellacani Lucio , Tardella Paolo A. 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1‐(N‐Acylamino)alkyltriphenylphosphonium Salts as Synthetic Equivalents of N‐Acylimines and New Effective α‐Amidoalkylating Agents.
Authors: Mazurkiewicz Roman , Pazdzierniok‐Holewa Agnieszka , Orlinska Beata , Stecko Sebastian 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhenium‐Catalyzed Insertion of Nonpolar and Polar Unsaturated Molecules into an Olefinic C—H Bond.
Authors: Kuninobu Yoichiro , Fujii Yasuo , Matsuki Takashi , Nishina Yuta , Takai Kazuhiko 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Fast and Efficient Method for the Preparation of Aryl Azides Using Stable Aryl Diazonium Silica Sulfates under Mild Conditions.
Authors: Zarei Amin , Hajipour Abdol R. , Khazdooz Leila , Aghaei Hamidreza 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ir(III) Complexes of Diamine Ligands for Asymmetric Ketone Hydrogenation.
Authors: Martins Jose E. D. , Wills Martin 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of p‐Quinols Using Catalytic Hypervalent Iodine Oxidation of 4‐Arylphenols with 4‐Iodophenoxyacetic Acid and Oxone®.
Authors: Yakura Takayuki , Omoto Masanori 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: One‐Pot Three Components Synthesis of O‐Acetylcyanohydrins with TMSCN, Acetic Anhydride and Carbonyl Compounds under Solvent‐Free Condition.
Authors: Kadam Santosh T. , Kim Sung Soo 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Oxidation of Sulfides with Hydrogen Peroxide Catalyzed by [SeO4{WO(O2)2}2]2‐.
Authors: Kamata Keigo , Hirano Tomohisa , Mizuno Noritaka 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pd—CNT‐Catalyzed Ligandless and Additive‐Free Heterogeneous Suzuki—Miyaura Cross‐Coupling of Aryl Bromides.
Authors: Zhang Pei‐Pei , Zhang Xin‐Xing , Sun Hui‐Xia , Liu Run‐Hua , Wang Bing , Lin Yang‐Hui 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Heterogenous Ru/CeO2 Catalyst Effective for Transfer‐Allylation from Homoallyl Alcohols to Aldehydes
Authors: Miura Hiroki , Wada Kenji , Hosokawa Saburo , Sai Masahiro , Kondo Teruyuki , Inoue Masashi 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Ionic Liquid Additive for Proline‐Catalyzed Direct Asymmetric Aldol Reactions Between Cyclic Ketones and Aromatic Aldehydes.
Authors: Qian Yunbo , Zheng Xin , Wang Xu , Xiao Shiyong , Wang Yongmei 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Organic Sensitizers Containing a Bulky Spirobifluorene Unit (I) for Solar Cell.
Authors: Cho Nara , Choi Hyunbong , Kim Duckhyun , Song Kihyung , Kang Moon‐sung , Kang Sang Ook , Ko Jaejung 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Asymmetric Synthesis of Chiral Hydroxy‐γ‐butyrolactones.
Authors: Davies Iwan R. , Cheeseman Matt , Green Rachel , Mahon Mary F. , Merritt Andrew , Bull Steven D. 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: CuBr‐Mediated Oxyalkylation of Vinylarenes under Aerobic Conditions via Cleavage of sp3 C—H Bonds α to Oxygen.
Authors: Cheng Kai , Huang Lehao , Zhang Yuhong 
Published: October 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.