bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weak parasitoid‐mediated apparent competition between two Phyllonorycter (Lepidoptera: Gracillariidae) leaf miner species on a deciduous oak Quercus dentata
Authors: NAKAMURA Takashi , KIMURA Masahito T. 
Published: September 2009

AbstractParasitoid assemblages and the rates of parasitism on tissue‐feeding larvae of two Phyllonorycter leaf miner species, P. persimilis and P. leucocorona, were studied from the autumn generation in 2002 to the summer generation in 2005 to understand whether parasitoids mediate interactions between the two leaf miner species. Fourteen species of parasitoids emerged from P. persimilis and 11 emerged from P. leucocorona. The parasitism rate was high: 24.1–92.6% in P. persimilis and 58.9–81.7% in P. leucocorona. Thus, parasitism was a major mortality factor in the present Phyllonorycter species. The parasitoid composition was distinctly different between the two host species, although most parasitoids were able to parasitize both leaf miner species. The analysis based on the quantitative parasitoid overlap revealed that the present parasitoids could mediate interactions between the present leaf miner species, but their effects would be weak. This is attributable to parasitoid's preferential uses of either of the leaf miners as a host.
Genus Thubana Walker in Indonesia, with descriptions of four new species (Lepidoptera: Lecithoceridae) and a world catalog of the genus
Authors: PARK Kyu‐Tek , HEPPNER John B. 
Published: September 2009

AbstractThe genus Thubana Walker (Lepidoptera: Lecithoceridae: Torodorinae) in Indonesia is reviewed, with three known species from Java and four additional new species: Th. raphidodea sp. nov. from Sulawesi, Indonesia and Malaysia; and Th. erycinae sp. nov., Th. apiculalis sp. nov. and Th. sellarius sp. nov. from Sumatra, Indonesia. The previously known species from Java, Th. costimaculella (Snellen), is redescribed for the wing venation and genitalia of both sexes; however, the syntype of Th. heylaertsi (Snellen) is observed only by its photograph. No specimens of Th. heylaertsi and Th. xylogramma Meyrick were found during this study. Photos of all known species, except Th. xylogramma Meyrick, and a key to species are provided. A catalog for the genus with all 46 known species in the world is given.
Cytologic and Histopathologic Evaluation of Extruded Canine Degenerate Disks
Authors: ROYAL ANGELA B. , CHIGERWE MUNASHE , COATES JOAN R. , WIEDMEYER CHARLES E. , BERENT LINDA M. 
Published: September 2009

Objective— To describe the cytologic and histopathologic appearance of degenerate disk material in dogs with Hansen type I intervertebral disk disease (IVDD).Study Design— Case series.Animals— Dogs (n=45) that had surgical intervention for Hansen type I IVDD (January–November 2007).Methods— Impression smears and histopathologic sections were prepared from surgically removed degenerate disk material. All slides were evaluated for overall cellularity, quantity and attributes of extracellular matrix, types of cells present, and their cytomorphology. Histopathologic sections were also examined for presence of neovascularization and hemorrhage.Results— Cytologically, 11 of 45 samples consisted of only extracellular matrix, 30 had evidence of inflammation, and 20 contained dysplastic spindloid cells. Histologically, hyaline cartilage predominated in 35 of 45 samples, fibrocartilage in 4, and spindloid cells in 6; 37 of 45 were inflamed, 37 were hemorrhagic, and 13 had neovascularization.Conclusions— The cytologic and histopathologic appearance of extruded degenerate disk material in dogs is variable and can include dysplastic spindloid cells.Clinical Relevance— The variability in cytologic findings and frequent presence of dysplastic spindloid cells suggest that cytology alone may not be a reliable tool to differentiate degenerate canine disk material from a mesenchymal neoplasm.
The Effect of Laparoscopic Versus Open Ovariectomy on Postsurgical Activity in Small Dogs
Authors: CULP WILLIAM T. N. , MAYHEW PHILIPP D. , BROWN DOROTHY C. 
Published: September 2009

Objective— To describe a technique for laparoscopic ovariectomy (LapOVE) in small dogs, and compare the surgical time, complications, and postoperative activity of dogs undergoing LapOVE to those undergoing conventional traditional open ovariectomy (OOVE).Study Design— A randomized, controlled clinical trial.Animals— Intact small breed (<10 kg) female dogs (n=20).Methods— Ventral median celiotomy was performed for OOVE. A 2‐midline portal technique using a 3.5 mm laparoscope port and a 6 mm instrument portal was used for LapOVE. An accelerometer was attached to the collar of each dog to record 24‐hour preoperative and 48‐hour postoperative activity. Total activity counts recorded before surgery were compared with total counts recorded after surgery. The percent change in counts after surgery was compared between OOVE‐ and LapOVE‐treated dogs.Results— No major complications occurred and surgical time for LapOVE was significantly longer than for OOVE cases (P=.005). Dogs in the LapOVE group had a 25% decrease in total activity counts after surgery (95% confidence interval [CI]: 11–38%), whereas dogs in the OOVE group had a 62% decrease in total activity counts after surgery (95% CI: 48–76%).Conclusions— Both procedures were performed with reasonable surgical times and without major complication. Postoperative activity, as measured by accelerometry, was significantly different between the 2 groups.Clinical Relevance— Laparoscopy is a safe method for ovariectomy in small dogs and results in increased postoperative activity counts when compared with an open technique.
A novel association of acquired ADAMTS13 inhibitor and acute dengue virus infection
Authors: Rossi Fernanda C. , Angerami Rodrigo N. , De Paula Erich V. , Orsi Fernanda L. , Shang Dezhi , Del Guercio Vânia M. , Resende Mariângela R. , Annichino‐Bizzacchi Joyce M. , Da Silva Luiz J. , Zheng X. Long , Castro Vagner 
Published: September 2009

BACKGROUND: Dengue is a mosquito‐borne viral disease with an increasing incidence worldwide. Thrombocytopenia is a common finding in dengue virus (DV) infection; however, the underlying mechanisms remain unknown.CASE REPORT: Here we provide the first evidence of a case of antibody formation against ADAMTS13 (ADAMTS13 inhibitor) in the course of a severe acute DV infection resulting in thrombotic microangiopathy (TMA). The patient presented with classical dengue symptoms (positive epidemiology, high fever, myalgia, predominantly in the lower limbs and lumbar region for 1 week) and, after 11 days of initial symptoms, developed TMA. Clinical and laboratorial investigation of dengue and TMA was performed.RESULTS: The patient presented with ADAMTS13 inhibitor (IgG) during the acute phase of the disease, without anti‐platelet antibodies detectable. Dengue infection had laboratorial confirmation. There were excellent clinical and laboratory responses to 11 serial plasma exchanges. Anti‐ADAMTS13 inhibitor disappeared after remission of TMA and dengue resolution. No recurrence of TMA symptoms was observed after 2‐year follow‐up.CONCLUSIONS: Although the real incidence of dengue‐related TMA is unknown, this case provides the basis for future epidemiologic studies on acquired ADAMTS13 deficiency in DV infection. The prompt clinical recognition of this complication and early installment of specific therapy with plasma exchange are likely to improve the outcome of severe cases of dengue.
Pharmacokinetic analysis of human plasma–derived pasteurized C1‐inhibitor concentrate in adults and children with hereditary angioedema: a prospective study
Authors: Martinez‐Saguer Inmaculada , Rusicke Eva , Aygören‐Pürsün Emel , Von Hentig Nils , Klingebiel Thomas , Kreuz Wolfhart 
Published: September 2009

BACKGROUND: Hereditary angioedema (HAE) is a rare and potentially life‐threatening disease presenting with acute edema of subcutaneous tissues and/or mucous membranes. Patients with HAE have abnormally low or dysfunctional C1‐inhibitor (C1‐INH). Preventing the progression of acute attacks is the main goal of C1‐INH replacement therapy; knowledge of the C1‐INH concentrate half‐life is of crucial importance. This pharmacokinetic study was conducted to investigate the pharmacokinetics of pasteurized human plasma–derived C1‐INH concentrate (pC1‐INH).STUDY DESIGN AND METHODS: This was a prospective, single‐center study of six children and 34 adults with an established diagnosis of HAE. On‐demand treatment with pC1‐INH was administered to all children, whereas adults received either pC1‐INH on‐demand treatment or individual replacement therapy (IRT). Functional C1‐INH plasma levels were fitted to a single‐compartment model with nonlinear regression, and the area under the curve was standardized to a dose equivalent of 15 U/kg body weight of pC1‐INH concentrate.RESULTS: The median half‐life of functional C1‐INH plasma levels in pediatric patients receiving on‐demand therapy was 32.9 hours (mean, 31.5 hr). In adults, the median half‐lives of functional C1‐INH plasma levels after on‐demand therapy were 39.1 hours (mean, 47.8 hr) and 30.9 hours (mean 33.3 hr) for patients on IRT. The median times to achieve maximum plasma activity after administration were 0.6 hour for children, 1.0 hour for adults receiving on‐demand treatment, and 0.5 hour for adults on IRT.CONCLUSIONS: pC1‐INH concentrate has a long median terminal elimination half‐life and rapidly reaches maximum plasma concentrations. This rapid onset of clinical efficacy is essential in patients suffering from HAE.
Oviposition preference in the oligophagous tomato fruit fly, Neoceratitis cyanescens
Authors: Brévault T. , Quilici S. 
Published: September 2009

AbstractWe assessed the role of visual and olfactory cues on oviposition preference in the oligophagous tomato fruit fly, Neoceratitis cyanescens (Bezzi) (Diptera: Tephritidae). In a field survey, we evaluated the stage of susceptibility of field‐grown tomatoes by monitoring N. cyanescens infestations from fruit‐setting up to harvest, in relation to post‐flowering time, size, and visual properties of fruit. In two‐choice laboratory experiments, we tested the degree to which females use visual and olfactory cues to select their host plant for oviposition. In addition, we investigated the ability of flies to avoid fruit already infested by conspecific eggs or larvae, and the influence of natal host fruit on oviposition preference. Neoceratitis cyanescens females preferentially lay their eggs in small yellow‐green unripe fruit (2–3.5 cm diameter, 10–21 days post‐flowering). Damage to fruit was significantly affected by brightness and size properties. In laboratory experiments, females chose to lay their eggs in bright orange rather than yellow domes. On the sole basis of olfactory stimuli, females showed a significant preference for unripe vs. ripe host fruit, for unripe fruit vs. flowers or leaves, and for host vs. non‐host fruit (or control). However, colour interacted with odour as females dispatched their eggs equally between the yellow dome and the bright orange dome when unripe fruit of tomato was placed under the yellow dome vs. ripe fruit under the bright orange dome. When offered real ripe and unripe tomatoes, females preferred unripe tomatoes. Females significantly chose to lay eggs in non‐infested fruit when they were given the choice between these or fruit infested with larvae. In contrast, recent stings containing eggs did not deter females from laying eggs. Rather, they could have an attractive effect when deposited within <1 h. Regardless of their natal host plant, tomato or bugweed, N. cyanescens females laid significantly more eggs in a dome containing bugweed fruit. However, 15% of females originating from tomato laid eggs exclusively in the dome with tomato, against 3% of females originating from bugweed.
Health‐related quality of life in health care workers with work‐related skin diseases
Authors: Matterne Uwe , Apfelbacher Christian Joachim , Soder Stefanie , Diepgen Thomas Ludwig , Weisshaar Elke 
Published: September 2009

Background: Occupational skin diseases (OSDs) are common among health care workers (HCWs). Little is known about how OSD impacts on health‐related quality of life (HRQoL) in HCWs with suspected OSD and associated factors.Objectives: To describe HRQoL in 278 HCWs with suspected OSD, compare data with the general and populations with skin diseases and analyse HRQoL's associations with clinical and demographic variables.Methods: HCWs with suspected OSD completed a generic (SF‐36) and specific (Skindex‐29) instrument.Results: Seven of 8 SF‐36 dimensions were significantly lower in HCWs than the general population. Compared with norms for patients with skin disease and cleaning and kitchen employees (CKEs) with suspected OSD, physical functioning (PF) and general health perception were less impaired in HCWs. Skindex‐29 scores were similar to CKEs' while they appeared better than patients' norms. Multivariate analysis found severity unrelated to SF‐36, apart from pain but associated with all Skindex‐29 scales.Conclusions: Although HCWs with suspected OSD display considerable HRQoL impairments, (general) PF and general health perception appear less affected than expected. Severity appears to affect specific and to a lesser extent general HRQoL. Clinical and demographic variables contributed moderately to the prediction of specific and little to the prediction of general HRQoL.
Delayed hypersensitivity to corticosteroids in a series of 315 patients: clinical data and patch test results
Authors: Baeck Marie , Chemelle Julie‐Anne , Terreux Raphaël , Drieghe Jacques , Goossens An 
Published: September 2009

Background: Corticosteroids may cause immediate or delayed hypersensitivity. In 1989, based on structural and clinical characteristics, we put forward a classification of corticosteroids into four cross‐reacting groups, namely group A, B, C, and D, the latter later subdivided into two subgroups, i.e. D1 and D2. The constituents on the D‐ring of the corticosteroid‐molecule are considered to have a central role for binding to skin proteins and for cross‐reactions patterns; however, halogenation of the molecules is also interfering.Objective: To study the clinical data and analyse simultaneous positive reactions obtained in a large group of corticosteroid‐allergic patients.Methods: Patch tests were performed with the baseline series, to which hydrocortisone butyrate and prednisolone caproate were added, as well as with the corticosteroids to which the patients had been exposed. Three hundred and forty subjects with a presumed or proven corticosteroid allergy were further investigated with an extended series containing 72 molecules.Results: Out of 11 596 patients investigated, 315 subjects reacted positively to at least 1 corticosteroid‐molecule, with most of them presenting with multiple positive reactions.Conclusion: A prevalence of corticosteroid allergy of 2.7% was found. Despite validity of the ABCD (sub)classification in many cases, possible adjustments may have to be considered.
Disorders of Pigmentation
Authors: Fistarol Susanna K. , Itin Peter H. 
Published: September 2009

SummarySkin color is highly individual and the variations are controlled by numerous genes. The different skin colors result from the size and number of melanosomes and do not mirror the amount of melanocytes. Disorders of pigmentation can result from migration abnormalities of melanocytes from the neural crest to the skin during embryogenesis. In addition, impairment of melanosome transfer to the surrounding keratinocytes, an alteration in melanin synthesis and a defective degradation or removal of melanin may lead to abnormal skin pigmentation. Immunologic or toxic mediated destructions of melanocytes can end in pigmentation disorders. Disorders of pigmentation are classified in hypo‐ or hyperpigmentation which can occur as a genetic or acquired disease. They can manifest locally or diffuse. Congenital hypopigmentation can be restricted to the skin as in piebaldism or they represent a systemic disease as in Menkes disease or phenylketonuria. Localized hypo‐ or hyperpigmentation in children may serve as markers for systemic diseases. Ash‐leaf hypopigmentation are characteristic for tuberous sclerosis and more than 5 café‐au‐lait spots suggest neurofibromatosis 1 (von Recklinghausen disease). The most common autoimmune‐induced depigmentation is vitiligo. Generalized hyperpigmentation only rarely reflects a primary genetic disorder but is most often from acquired diseases as in Addison disease, secondary hemochromatosis or primary biliary cirrhosis. Treatment of pigmentation disorders are based on a diagnosis which sometimes allow a specific intervention. Cosmetically acceptable results are difficult to obtain.
Emotional reactivity in infants with congenital heart defects: findings from a large case‐cohort study in Norway
Authors: Stene‐Larsen K , Brandlistuen RE , Holmstrøm H , Landolt MA , Eskedal LT , Vollrath ME 
Published: September 2009

AbstractAim:  Advances in medical treatment in recent years have led to dramatically improved survival rates of children with severe congenital heart defects (CHD). However, very little is known about the psychological consequences for these children, particularly during and after the early period of invasive treatment. In this study, we investigated the extent to which the severity of the CHD affects the child’s emotional reactivity at 6 months of age.Method:  We linked prospective data from the Norwegian Mother and Child Cohort Study, conducted by the Norwegian Institute of Public Health with a nationwide medical CHD registry and identified 212 infants with CHD in a cohort of 61 299 infants. Mothers reported on their child’s emotional reactivity at age 6 months by means of a standardized questionnaire.Results:  Infants with severe to moderate CHD had 60% higher odds for severe emotional reactivity (cut‐off at the 85 percentile) compared with healthy infants, after controlling for important maternal and child confounders.Conclusion:  Our study is the first to show elevated emotional reactivity in children with moderate to severe CHD, suggesting a need for special parental attention to soothe their distress. Follow‐up studies will show whether this emotional reactivity is transient or an early marker of continuing emotional or behavioural problems.
IGF‐I, leptin and active ghrelin levels in very low birth weight infants during the first 8 weeks of life
Authors: Ohkawa N , Shoji H , Kitamura T , Suganuma H , Yoshikawa N , Suzuki M , Lee T , Hisata K , Shimizu T 
Published: September 2009

AbstractAim:  We investigated the relationship between plasma insulin‐like growth factor I (IGF‐I), leptin, active ghrelin levels, and postnatal growth in very low birth weight (VLBW) infants.Method:  Plasma IGF‐I, leptin, and active ghrelin levels were measured at birth and at 2, 4, 6 and 8 weeks after birth in 61 VLBW infants, including 31 appropriate‐for‐gestational‐age (AGA) and 30 small‐for‐gestational‐age (SGA) infants.Results:  Insulin‐like growth factor I levels were the lowest at birth, but increased gradually over the first 8 weeks of life. IGF‐I was positively correlated with body weight, body length and body mass index at all time points. Leptin levels did not change over the study period. Ghrelin levels were significantly lower at birth; however, there were no significant differences between the levels after 2 weeks of age. Leptin and ghrelin levels were not correlated with anthropometrical measures. IGF‐I levels at birth were significantly lower in SGA than in AGA infants, but the leptin and ghrelin levels were not significantly different between the two groups.Conclusion:  Insulin‐like growth factor I is related to length and weight gain in the prenatal and the early postnatal periods in VLBW infants, but this does not appear to be the case for leptin and ghrelin.
Breastfeeding practice in mothers with eating disorders
Authors: Torgersen Leila , Ystrom Eivind , Haugen Margaretha , Meltzer Helle M. , Von Holle Ann , Berg Cecilie Knoph , Reichborn‐Kjennerud Ted , Bulik Cynthia M. 
Published: September 2009

AbstractThe purpose of this study was to compare the prevalence of breastfeeding in women with anorexia nervosa, bulimia nervosa, binge eating disorder and eating disorders not otherwise specified – purging subtype, with mothers with no eating disorders during the first 6 months after birth. The study is based on the Norwegian Mother and Child Cohort Study conducted at the Norwegian Institute of Public Health. Questionnaire‐based information on eating disorder diagnoses and breastfeeding in 39 355 women was used to estimate the risk of cessation of breastfeeding with Cox proportional hazards regression. Almost all women (98%) initially breastfeed their infants, with no statistically significant difference between the eating disorders subgroups and women with no eating disorders. However, the risk of early cessation before 6 months post‐partum increased for all subgroups of mothers with eating disorders, compared with mothers with no eating disorders. After adjusting for maternal body mass index, age, education, birthweight and pre‐term birth, only mothers with anorexia nervosa [hazard ratios (HR), 2.35; 95% confidence interval (CI) 1.22–4.53] and eating disorder not otherwise specified‐purging subtype (HR, 1.95; 95% CI 1.08–3.53) had increased risk for cessation of breastfeeding There were no differences in the risk of cessation of exclusive breastfeeding. These results show that some eating disorders may influence mothers' early feeding practices and indicate that additional support may be necessary to assist women with anorexia nervosa in maintaining breastfeeding.
Oral health‐related quality of life in patients receiving home‐care nursing: associations with aspects of dental status and xerostomia
Authors: Willumsen Tiril , Fjaera Brit , Eide Hilde 
Published: September 2009

doi:10.1111/j.1741‐2358.2009.00344.x

Oral health‐related quality of life in patients receiving home‐care nursing: associations with aspects of dental status and xerostomia Objective:  To explore the differences in oral status, dental attendance and dry mouth problems between patients with long‐term disease with high and low scores on Oral Health Impact Profile 14 (OHIP 14) and how patients cope with oral problems such as xerostomia and a reduced ability to brush their teeth.Background:  There has been a lack of studies of oral health and oral health‐related quality of life in the frail elderly within the community services.Materials and methods:  A cross‐sectional questionnaire study was conducted with 137 patients receiving home‐care nursing. Structured interviews were conducted by student nurses using OHIP‐14, items from the Xerostomia Inventory and questions concerning dental visit habits, brushing of teeth and data from medical records.Results:  Eighty‐three per cent of patients had natural teeth and 60% had only natural teeth. ‘Natural teeth only’ indicated a low score on OHIP‐14. Problems with brushing and items concerning xerostomia indicated a high score on OHIP‐14. Contrasts in the assessments concerning brushing of teeth and xerostomia indicated low priority from the patients themselves and the nursing staff.Conclusion:  Community health services should focus upon oral health. Both patients and nurses should assess the need for regular brushing of teeth carried out by home‐care nurses. Assessment and treatment of dry mouth problems should have higher priority.