bluuebunny/crossref_metadata_2025_split huggingface dataset:
Addition of eptifibatide and manual thrombus aspiration to ticagrelor does not improve long-term survival after STEMI treated with primary PCI
Authors: Călburean Paul-Adrian , Grebenișan Paul , Nistor Ioana-Andreea , Pal Krisztina , Vacariu Victor , Drincal Reka-Katalin , Ion Alissa Anamaria , Adorján István , Oltean Tiberiu , Hadadi László 
Published: June 2024

Background: Current guidelines recommend that glycoprotein IIb/IIIa inhibitor (GPI) and manual aspiration thrombectomy should not be routinely used in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (pPCI), although there is a lack of dedicated studies. The aim of this study was to examine the impact of combined usage of a potent P2Y12 inhibitor, GPI, and manual aspiration thrombectomy on long-term survival after STEMI.Methods: All STEMI patients treated by pPCI in a tertiary center who have been included prospectively in the local PCI registry between January 2016 and December 2022 were analyzed in this study. Patients were excluded if they required oral anticoagulation or bridging between clopidogrel or ticagrelor during hospitalization.Results: A total of 1,210 patients were included in the present study, with a median follow-up of 2.78 (1.00–4.88) years. Ticagrelor significantly reduced all-cause and cardiovascular-cause mortality [HR = 0.27 (0.21–0.34), p &lt; 0.0001 and HR = 0.23 (0.17–0.30), p &lt; 0.0001, respectively]. Eptifibatide significantly reduced all-cause and cardiovascular-cause mortality [HR = 0.72 (0.57–0.92), p = 0.002, and HR = 0.68 (0.52–0.89), p = 0.001, respectively]. Manual thrombus aspiration had no significant effect on both all-cause and cardiovascular-cause mortality. In multivariate Cox regression, all-cause mortality was reduced by ticagrelor, while eptifibatide or manual thrombus aspiration had no significant effect. However, cardiovascular-cause mortality was reduced by both ticagrelor and eptifibatide, while manual thrombus aspiration had no significant effect.Conclusion: Ticagrelor consistently reduced cardiovascular and all-cause mortality, while eptifibatide reduced only cardiovascular mortality. Manual thrombus aspiration provided no long-term benefit. Our findings support the current guideline recommendation that GPI and manual aspiration thrombectomy should not be routinely used in treatment of STEMI with pPCI.
Harnessing plant growth-promoting rhizobacteria, Bacillus subtilis and B. aryabhattai to combat salt stress in rice: a study on the regulation of antioxidant defense, ion homeostasis, and photosynthetic parameters
Authors: Siddika Ayesha , Rashid Alfi Anjum , Khan Shakila Nargis , Khatun Amena , Karim Muhammad Manjurul , Prasad P.V. Vara , Hasanuzzaman Mirza 
Published: June 2024

IntroductionThe ongoing global expansion of salt-affected land is a significant factor, limiting the growth and yield of crops, particularly rice (Oryza sativa L). This experiment explores the mitigation of salt-induced damage in rice (cv BRRI dhan100) following the application of plant growth-promoting rhizobacteria (PGPR).MethodsRice seedlings, at five- and six-weeks post-transplanting, were subjected to salt stress treatments using 50 and 100 mM NaCl at seven-day intervals. Bacterial cultures consisting of endophytic PGPR (Bacillus subtilis and B. aryabhattai) and an epiphytic PGPR (B. aryabhattai) were administered at three critical stages: transplantation of 42-day-old seedlings, vegetative stage at five weeks post-transplantation, and panicle initiation stage at seven weeks post-transplantation.ResultsSalt stress induced osmotic stress, ionic imbalances, and oxidative damage in rice plants, with consequent negative effects on growth, decrease in photosynthetic efficiency, and changes in hormonal regulation, along with increased methylglyoxal (MG) toxicity. PGPR treatment alleviated salinity effects by improving plant antioxidant defenses, restoring ionic equilibrium, enhancing water balance, increasing nutrient uptake, improving photosynthetic attributes, bolstering hormone synthesis, and enhancing MG detoxification.DiscussionThese findings highlight the potential of PGPR to bolster physiological and biochemical functionality in rice by serving as an effective buffer against salt stress–induced damage. B. subtilis showed the greatest benefits, while both the endophytic and epiphytic B. aryabhattai had commendable effects in mitigating salt stress–induced damage in rice plants.
The relationship between mental health literacy and professional psychological help-seeking behavior among Chinese college students: mediating roles of perceived social support and psychological help-seeking stigma
Authors: Yang Xiao , Hu Jun , Zhang Bingren , Ding Hua , Hu Danying , Li Hangdong 
Published: June 2024

IntroductionMental health literacy is viewed as a significant factor that may facilitate an individual’s pursuit of professional psychological assistance. However, it is important to explore further influencing factors that might underlie this association. This study, employing the framework of the Theory of Planned Behavior (TPB), aims to examine the relationship between mental health literacy and the behavior of seeking professional psychological help, with a focus on the potential mediating roles of perceived stigma and social support in this context.MethodsWe surveyed 911 college students in seven regions of China (406 males and 505 females, aged between 19 and 25 years old; Mage = 19.65, SD = 1.41) utilizing self-report measures, including the Mental Health Literacy Questionnaire, Professional Psychological Help-Seeking Behavior Scale, Professional Psychological Help-Seeking Stigma Scale, and Perceived Social Support Scale. A chain mediation model was developed to analyze the interconnections between mental health literacy, stigma related to seeking psychological help, perceived social support, and professional psychological help-seeking behaviors.ResultsThe mediation effect analysis indicates that: (1) mental health literacy significantly positively correlates with professional psychological help-seeking behaviors; (2) both perceived social support and professional psychological help-seeking stigma significantly mediate the relationship between mental health literacy and professional psychological help-seeking behavior; (3) perceived social support and the stigma associated with seeking professional psychological help play a chained mediating effect between mental health literacy and the behavior of seeking professional psychological help.DiscussionThis study found that mental health literacy indirectly facilitates professional psychological help-seeking behaviors by enhancing the perception of social support and reducing the stigma associated with seeking such help. These findings help in understanding how improving mental health literacy and perceived social support while reducing stigma can increase the likelihood of individuals seeking professional psychological assistance. The results are significant for enhancing the utilization of mental health services and implementing mental health education programs in universities.
Predisposing factors of using cosmetics in Iranian female students: application of prototype willingness model
Authors: Moslehi Shandiz , Tavan Asghar , Narimani Sajjad , Ahmadi Fatemeh , Kazemzadeh Masoomeh , Sedri Nadia 
Published: June 2024

Background and aimThe use of cosmetics among Iranian teenagers and youths has increased more than ever before. This study investigated the predisposing factors of cosmetic use in female students of Ardabil University of Medical Sciences by using the prototype willingness model (PWM).MethodsThis cross-sectional study was conducted with 384 students, selected based on multistage sampling. Data were collected using a two-part questionnaire that included demographic variables and PWM questions. Then multiple regression analysis was used in SPSS (version 20).ResultsThere was a significant difference in the frequency of daily cosmetic use based on the education levels (F = 3.845, p-value = 0.034). The average daily use of cosmetics was higher in students whose use of cosmetics was high in their family (p = 0.024) and friends (p-value = 0.023). Prototypes were the strongest predictor of using cosmetics (OR = 1.317, p-value &lt;0.001), followed by attitude (OR = 1.241, p-value &lt;0.001).ConclusionPrototypes (social imagination) and attitudes were the main predictors of using cosmetics among female students. To be effective in targeting cosmetic use, interventions must target both social and individual paths.
Social media users’ attitudes toward cyberbullying during the COVID-19 pandemic: associations with gender and verification status
Authors: Li Lifang , Zhou Jiandong , McManus Sally , Stewart Robert , Roberts Angus 
Published: June 2024

IntroductionSocial media platforms such as Twitter and Weibo facilitate both positive and negative communication, including cyberbullying. Empirical evidence has revealed that cyberbullying increases when public crises occur, that such behavior is gendered, and that social media user account verification may deter it. However, the association of gender and verification status with cyberbullying is underexplored. This study aims to address this gap by examining how Weibo users’ gender, verification status, and expression of affect and anger in posts influence cyberbullying attitudes. Specifically, it investigates how these factors differ between posts pro- and anti-cyberbullying of COVID-19 cases during the pandemic.MethodsThis study utilized social role theory, the Barlett and Gentile Cyberbullying Model, and general strain theory as theoretical frameworks. We applied text classification techniques to identify pro-cyberbullying and anti-cyberbullying posts on Weibo. Subsequently, we used a standardized mean difference method to compare the emotional content of these posts. Our analysis focused on the prevalence of affective and anger-related expressions, particularly examining variations across gender and verification status of the users.ResultsOur text classification identified distinct pro-cyberbullying and anti-cyberbullying posts. The standardized mean difference analysis revealed that pro-cyberbullying posts contained significantly more emotional content compared to anti-cyberbullying posts. Further, within the pro-cyberbullying category, posts by verified female users exhibited a higher frequency of anger-related words than those by other users.DiscussionThe findings from this study can enhance researchers’ algorithms for identifying cyberbullying attitudes, refine the characterization of cyberbullying behavior using real-world social media data through the integration of the mentioned theories, and help government bodies improve their cyberbullying monitoring especially in the context of public health crises.
A realist evaluation of community champion and participatory action approaches during the COVID-19 pandemic
Authors: Howlett Neil , Fakoya Olujoke , Bontoft Charis , Simmons Isobel , Miners Lisa , Wagner Adam P. , Brown Katherine 
Published: June 2024

BackgroundDuring the COVID-19 pandemic, public health teams tried several approaches to circulate accurate health information and engage with community members to understand what they need from public health services. Two such approaches were community champions and community participatory action research (CPAR). This study evaluates two champion programmes and a CPAR programme in terms of what worked, for whom, and in what contexts, including the funding and resourcing associated with implementation.MethodsBetween June 2022 and June 2023, a realist evaluation of three distinct case studies (COVID-19 champions, Vaccine Champions, and CPAR programmes) in the city of Southampton in England was conducted in three stages: development of initial programme theories and collection of additional contextual information, including funding and resources associated with delivering each programme; initial programme theory testing; synthesis of final programme theories. Data was collected primarily through semi-structured interviews (n = 29) across programme and training leads, voluntary services, community organisations, volunteers, and local community members, and one focus group with local community members (n = 8).ResultsThe City Council used £642 k from two funding awards to deliver the programmes: COVID-19 Champions £41 k; Vaccine Champions £485 k; and CPAR programmes £115 k. Twenty-eight initial programme theories were generated, which were “tested” to support, refine, or refute context-mechanism-outcome relationships, resulting finally in a set of 22 programme theories across the three programmes. Six demi-regularities were generated, each featuring in multiple programme theories, and providing data on how and why these programmes can work, and in which contexts: (1) building trust through community connections; (2) fostering relationships and collaboration; (3) provision of training and resources; (4) local community knowledge and expertise; (5) community representation and leadership; (6) appropriate communication and information sharing.ConclusionThis study provides new knowledge and understanding of the factors affecting the implementation of community champion and CPAR approaches during public health emergencies. These findings suggest that representation and involvement of community members, establishing and building on trust, adequate training and resources, and clear communication from trusted community members and organisations are catalysts for meaningful engagement with communities.Evaluation registration: Research Registry identifier: researchregistry8094.
Exploring the personal benefits of surfing: insights from cold-water surfers in Jæren, Norway
Authors: Elmahdy Yasmine M. , Orams Mark , Mykletun Reidar J. 
Published: June 2024

IntroductionSurfing has grown since the 1960s to become a global marine leisure activity. Traditionally, surfing is associated with tropical and temperate climates and a sea, sand, and sun setting. However, surfing's geographical spread now includes polar and sub-polar regions, areas where the cold and sea-conditions provide challenges to human survival.MethodsThis study uses a phenomenological approach to identify and explore the personal benefits gained by experienced surfers in the Jæren region, south of the city of Stavanger in Norway. Data were obtained from semi-structured in-depth interviews with 13 experienced surfers who surf year-round, but primarily in winter, in extreme conditions. Additional secondary data were derived from written and video material published in online surfing blogs/vlogs and surfers' private video footage.Results and discussionParticipants gained a wide range of benefits including experiencing strong positive feelings, inclusion, and social cohesion with other members in the surfing subculture, a deep connection to nature, physical and mental health benefits, and an overall enhanced quality of life. While international surf travel was constrained by the COVID-19 pandemic, local surfing was reinforced. This resulted in surfing becoming an opportunity to safely socialize with others outside of one's family, thus increasing the social benefits of the sport. This study presents the first empirical data on the personal benefits of surfing from a non-traditional cold-water surfing nation in Scandinavia.
Gallium Isotope Effect of Ga-Si Complex Solutions in Water: Theoretical Study Based on Density Functional Theory
Authors: Zhang Jixi 
Published: June 2024

A Ga isotope is a new proxy for different geochemical processes such as a weathering process, solution process, etc. Si (Si(OH)4) is ubiquitous in natural water bodies. However, studies on the Ga isotope effect about a Ga3+ aqueous solution reacting with Si (Si(OH)4) are lacking. In this study, the Ga isotope effect of this process will be studied using a theoretical calculation method based on first principles. The results show that the heavy Ga (71Ga) isotope enrichment ability of different Ga-Si complex solutions is different. The 1000lnβ (‰) sequence of different Ga-Si complex solutions is (OH)3GaOSi(OH)3.(H2O)30 ≈ (OH)3(H2O)2GaOSi(OH)3.(H2O)30 > (OH)2(H2O)3GaOSi(OH)3.(H2O)30 > (H2O)5GaOSi(OH)3.(H2O)30 > (OH)(H2O)4GaOSi(OH)3.(H2O)30. The results show that there are two different reaction mechanisms when a Ga3+ aqueous solution reacts with Si-bearing (Si(OH)4) water; that is, six-coordination Ga-Si complexes and four-coordination Ga-Si complexes are formed at low pH (acidic) and high pH (alkaline), respectively. Compared with a Ga-Si complex aqueous solution under acidic conditions, Ga-Si aqueous solutions under alkaline conditions preferentially enriched the heavy Ga isotope (71Ga). The Ga isotope fractionation factors (α) between Ga-Si complex solutions and Ga3+-bearing aqueous solutions are all negative, which indicates that light Ga (69Ga) isotopes preferentially enter the structure of Ga-Si complexes during the formation of Ga-Si complex solutions. At 50 °C, the Ga isotope fractionation factors (1000lnα) of five systems ((H2O)5GaOSi(OH)3.(H2O)30 vs. [Ga(H2O)6]3+(aq), (OH)(H2O)4GaOSi(OH)3.(H2O)30 vs. [Ga(H2O)6]3+(aq), (OH)3GaOSi(OH)3.(H2O)30 vs. [Ga(OH)3](aq), (OH)3(H2O)2GaOSi(OH)3.(H2O)30 vs. [Ga(OH)3](aq), and (OH)2(H2O)3GaOSi(OH)3.(H2O)30 vs. [Ga(OH)3](aq)) involved in this study are −0.12, −0.22, −0.07, −0.09, and −0.16 (‰), respectively. Excitedly, Si can affect the enrichment ability of the heavy Ga isotope (71Ga) in Ga-bearing complex aqueous solutions. This means that when Si is present in aqueous solutions, the enrichment capacity of the heavy Ga isotope (71Ga) of aqueous solutions will be effectively reduced. Ga in sediments is mainly derived from soluble Ga in the form of adsorbed (Fe, Mn) oxides/hydroxides, and the Ga isotope composition in sediments is heavier than that in basalt. The formation process of Ga-Si complex aqueous solutions influences the Ga isotope fractionation effect and also contributes to the composition of Ga isotopes in sediments. These key Ga isotope fractionation parameters obtained in this study will provide theoretical support for better explaining the reaction mechanism of Ga3+ complexes and Si-bearing (Si(OH)4) water bodies in solution processes and Ga isotope geochemical cycles.
Sonographic Assessment of Retrograde Blood Flow for External Nose Reconstruction Using Interpolation Flaps
Authors: Иванов С.А. , Юрковский А.М. , Хоров О.Г. , Лазарева Н.Ф. 
Published: June 2024

Цель. Оценить эффективность сонографической оценки ретроградного кровотока в интерполяционных лоскутах при реконструкции наружного носа. Материалы и методы. Сравнены результаты реконструкции наружного носа с использованием клинического метода (37 пациентов, группа 1) и цветного доплеровского картирования (29 пациентов, группа 2) при оценке ретроградного кровотока в интерполяционных лоскутах. Результаты. Частота ишемических осложнений со стороны лоскута была выше при клинической оценке ретроградного кровотока (8 из 37 пациентов, 23,5%) по сравнению с сонографической оценкой (1 из 29 пациентов, 3,4%), различие является статистически значимым, p=0,036. Интервал между формированием лоскута и пересечением ножки в группе 1 составил 34 (29; 38) дня, в группе 2 – 30 (27; 35) дней, различие не имеет статистической значимости, p=0,064. Распределение оценок вида носа не показало статистической значимости по данным опроса как пациентов (р=0,170), так и экспертов (р=0,075). Доля неприемлемых косметических результатов, по оценке экспертов, была выше в группе 1 (24,3%, 9 из 37) по сравнению с группой 2 (3,4%, 1 из 29), различие статистически значимое, р=0,035. Выводы. Использование сонографической оценки ретроградного кровотока в интерполяционных лоскутах при реконструкции наружного носа позволяет снизить частоту осложнений и уменьшить долю неприемлемых косметических результатов по сравнению с клинической оценкой.
Purpose. To evaluate the effectiveness of sonographic assessment of retrograde blood flow in nasal reconstruction using interpolation flaps. Materials and methods. Reconstruction outcomes were compared in two patient groups. Clinical assessment of retrograde blood flow was performed to in 37 patients (group 1) and sonographic method was performed to in 29 patients (group 2). Results. Flap ischemic complication rate after using of sonographic assessment of retrograde blood flow (1 of 29 patients, 3.4%) was lower than after clinical assessment (8 of 37 patients, 23.5%). Difference was statistically significant, p=0.036. The time between the flap elevation and pedicle division was 34 (29; 38) days in group 1 and 30 (27; 35) days in group 2. Difference wasn`t statistically significant, p=0.064. Cosmetic outcome scores by experts` and patients` questioning didn`t show statistically significant difference, р=0.075 and р=0.170, respectively. Rate of unacceptable cosmetic outcomes by experts` scores in group 1 (24.3%, 9 of 37) was statistically significant higher than in group 2 (3.4%, 1 of 29), р=0.035. Conclusions. The use of sonographic assessment of retrograde blood flow in nasal reconstruction with interpolation flaps can reduce the complications rate and reduce the rate of unacceptable cosmetic results compared with clinical assessment.
Implementasi Pijat Bayi sebagai Upaya Pencegahan Stunting pada Anak Balita di Wilayah Kelurahan Candirejo, Kecamatan Ungaran Barat Kabupaten Semarang
Authors: Siti Haryani  , Ana Puji Astuti  , Kartika Sari  
Published: June 2024

Stunting is a problem that needs special attention. The result of stunting can cause growth and development to be inhibited. One of the efforts to reduce the incidence of stunting is baby massage. The purpose of this activity is to provide an overview of the baby massage procedure. The method used is to provide health counselling with a demonstration method of baby massage procedures. The target of this activity is mothers who have toddlers. The stages carried out include providing material about baby massage followed by a demonstration of baby massage. At the evaluation stage, participants demonstrated the baby massage that had been taught. The result of this activity was that 90% of the participants could explain and demonstrate the baby massage procedur
ABSTRAK
Stunting merupakan masalah yang perlu mendapatkan perhatian khusus. Akibat stunting dapat menyebabkan pertumbuhan dan perkembangan menjadi terhambat. Salah satu upaya untuk menurunkan kejadian stunting adalah dengan pijat bayi. Tujuan dari kegiatan ini adalah untuk memberikan gambaran tenatng prosedur pijat bayi. Metode yang digunakan adalah memberikan penyuluhan kesehatan dengan metode demonstrasi prosedur pijat bayi. Sasaran pada kegiatan ini adalah ibu yang mempunyai balita. Tahapan yang dilakukan meliputi pemberian materi tentang pijat bayi dilanjutkan demonstrasi pijat bayi. Pada tahap evaluasi dilakukan dengan peserta mendemonstrasikan kembali pijat bayi yang telah diajarkan. Hasil dari kegiatan ini adalah peserta 90% dapat menjelaskan dan mendemonstrasikan kembali tentang prosedur pijat bayi