bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Carbonylation of Enolizable Ketones (Enol Triflates) and Iodoalkenes
Authors: Arcadi Antonio 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbonylation of Alkenes and Dienes
Authors: Kegl Tamas 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transformation Chemistry with Nucleic Acid Purines
Authors: Robins Morris J. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Electrical Conductance of Single Molecules: A Challenge in the Series of Conjugated Oligomers
Authors: Meier Herbert 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Binding Mechanisms in Supramolecular Complexes
Authors: Schneider Hans‐Joerg 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Maximizing Multivalency Effects in Protein—Carbohydrate Interactions
Authors: Pieters Roland J. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Leflunomide in Solid Organ Transplantation and Polyoma Virus Infection
Authors: Josephson Michelle A. , Javaid Basit , Kadambi Pradeep V. , Meehan Shane M. , Williams James W. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrode Materials and Reaction Mechanisms in Solid Oxide Fuel Cells: A Brief Review
Authors: Tsipis Ekaterina V. , Kharton Vladislav V. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bioinspired Polymers for Nanoscience Research
Authors: Lee Byoung‐Chul , Connolly Michael D. , Zuckermann Ronald N. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biosynthesis of Aromatic Polyketides in Bacteria
Authors: Das Abhirup , Khosla Chaitan 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Is Enantioselectivity Predictable in Asymmetric Catalysis?
Authors: Brown John M. , Deeth Robert J. 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular Imaging by PET/SPECT
Authors: Ono Masahiro 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Consideration on Molecular Imaging Technology as a Tool for Drug Research and Development
Authors: Yajima Kazuyoshi , Nishimura Shintaro 
Published: July 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Recyclable Merrifield resin‐supported organocatalysts containing pyrrolidine unit through A3‐coupling reaction linkage for asymmetric Michael addition
Authors: Liu Jie , Li Pinhua , Zhang Yicheng , Ren Kai , Wang Lei , Wang Guanwu 
Published: July 2009

AbstractMerrifield resin‐supported pyrrolidine‐based chiral organocatalysts A−D through A3‐coupling reaction linkage have been developed and found to be highly effective catalysts for the Michael addition reaction of ketones with nitrostyrenes. The reactions generated the corresponding products in good yields (up to 92%), excellent enantioselectivities (up to 98% ee), and high diastereoselectivities (up to 99:1 dr). In addition, the catalysts can be reused at least five times without a significant loss of catalytic activity and stereoselectivity. Chirality, 2010. © 2009 Wiley‐Liss, Inc.
The Influence of Anemia After Percutaneous Coronary Intervention on Clinical Outcomes
Authors: Sattur Sudhakar , Harjai Kishore J. , Narula Arvin , Devarakonda Srinivas , Orshaw Pamela , Yaeger Karl 
Published: July 2009

AbstractBackgroundAlthough the consequences of bleeding after percutaneous coronary intervention (PCI) are well documented, there are no data on the impact of post‐PCI anemia (PPA) on clinical outcomes.MethodsWe evaluated the incidence, predictors, and prognostic implications of PPA on clinical outcomes in 1415 PCI procedures. We compared clinical outcomes of patients with PPA (ie, nadir post‐PCI hemoglobin < 10 gm/dL) vs without PPA. In patients with PPA, we assessed the influence of thrombolysis in myocardial infarction (TIMI; major or minor) bleeding, drop in hemoglobin by ≥ 3 gm/dL, and use of blood transfusions on outcomes.ResultsPost‐PCI anemia developed in 124 (8.8%) patients. Of these, 50 (40%) suffered TIMI (major or minor) bleeding, 68 (55%) had a hemoglobin drop of ≥ 3 gm/dL, and 39 (32%) patients received blood transfusions. Compared to patients without PPA, those with PPA had greater incidence of 6 month death (6.5% vs 1.7 %, p = 0.003), 6 month major adverse cardiovascular event (MACE; death, reinfarction, or target vessel revascularization; 27.3% vs 14.5%, p = 0.0006), and long‐term mortality (25.8% vs 8.7 %, p ≤ 0.0001). After adjustment for baseline differences, PPA showed an independent association with 6 month MACE (odds ratio [OR]: 2.4, 95% confidence interval [CI]: 1.5–3.9) and long‐term mortality (hazard ratio [HR]: 1.3, 95% CI: 1.0–1.6). In patients who developed PPA, the occurrence of TIMI (major or minor) bleeding, hemoglobin drop of ≥ 3 gm/dL, and use of blood transfusions did not impact outcomes.conclusionWe found that PPA is common, occurs frequently in the absence of bleeding or significant drop in hemoglobin, and connotes poor long‐term outcomes. Copyright © 2009 Wiley Periodicals, Inc.
Thyroid Hormone and Coronary Artery Disease: From Clinical Correlations to Prognostic Implications
Authors: Coceani Michele , Iervasi Giorgio , Pingitore Alessandro , Carpeggiani Clara , L'Abbate Antonio 
Published: July 2009

AbstractBackgroundOvert thyroid dysfunction, hypothyroidism in particular, may lead to coronary artery disease (CAD). Whether more subtle anomalies of thyroid hormone metabolism influence the progression of CAD remains a matter of speculation.HypothesisThe occurrence of CAD and long‐term prognosis in patients without a history of either primary thyroid disease, myocardial infarction, or chronic heart failure is related to serum levels of biologically active free triiodothyronine (fT3).MethodsThe cohort consisted of 1047 clinically and biochemically euthyroid patients (median age 65.6 y and 69% male) who underwent coronary angiography in our institute for suspected CAD.ResultsLower fT3 levels were predictive of both single‐vessel (p = 0.012) and multivessel (p = 0.009) CAD. Through a multivariate logistic regression analysis, fT3 was still linked to the presence of CAD (hazard ratio [HR]: 0.48, 95% confidence interval [CI]: 0.34–0.68, p < 0.001). After a mean follow‐up of 31 months, the survival rate was 95% and total mortality (log‐rank 6.75, p = 0.009), as well as cardiac mortality (log‐rank 8.26, p = 0.004), was greater among patients with low T3 (fT3 < 2.10 pg/mL) syndrome. At subsequent multivariate Cox regression analysis, the association between low T3 syndrome and survival was maintained (total mortality HR: 1.80, 95% CI: 1.05–3.10, p = 0.034; cardiac mortality HR: 2.58, 95% CI: 1.13–5.93, p = 0.025).ConclusionsIn this selected population, fT3 levels were inversely correlated to the presence of CAD and low T3 syndrome conferred an adverse prognosis, even after adjusting for traditional coronary risk factors. Copyright © 2009 Wiley Periodicals, Inc.
β‐Blocker Use in Heart Failure Patients with Airways Disease
Authors: Shaw Steven M. , Hasleton Jonathan , Williams Simon G. 
Published: July 2009

AbstractBackgroundβ‐Blockers are often withheld from patients with obstructive airways disease, especially those with reversible airways disease due to fear of inducing bronchospasm. We report our single center experience of cautiously treating such patients who have concomitant chronic heart failure (CHF).HypothesisThe use of cardioselective β‐blockers under caution and specialist supervision may be tolerable in many CHF patients with obstructive airways disease, resulting in clinical improvement rather than detriment.MethodsA retrospective case notes analysis was performed on CHF outpatients who had obstructive airways disease and been treated with β‐blockers.ResultsA total of 43 patients were identified, with an average ejection fraction of 31.8%; 18 of these patients had fixed obstructive airways disease, 15 patients had reversible obstructive airways disease, 10 patients had a label of obstructive airways disease (but no supporting evidence for the diagnosis in the hospital notes). In all 3 groups, β‐blockers had been initiated and maintained without any respiratory event over a median continuous exposure time of 135 days. Limitation of the dose was documented in only 2 patients because of worsening shortness of breath. New York Heart Association (NYHA) class significantly improved for the group with the use of these agents (p = 0.003).ConclusionA cautious approach (under specialist supervision) to β‐blocker use in patients with heart failure and airways disease can result in successful treatment. The implications of withholding these agents may have more serious consequences than their administration. Copyright © 2009 Wiley Periodicals, Inc.
Left Ventricular Outflow Tract Gradient Variability in Hypertrophic Cardiomyopathy
Authors: Geske Jeffrey B. , Sorajja Paul , Ommen Steve R. , Nishimura Rick A. 
Published: July 2009

AbstractBackgroundThe presence and magnitude of left ventricular outflow tract (LVOT) obstruction directs the management algorithm in symptomatic patients with hypertrophic cardiomyopathy (HCM). Although it is well known that the degree of LVOT obstruction is dynamic and dependent upon ventricular load and contractility, the magnitude and potential impact of the day‐to‐day variability seen in practice has not been well appreciated.HypothesesWe hypothesized that LVOT gradient variability in HCM has an impact on clinical decision‐making.MethodsA total of 100 HCM patients (mean age, 58 ± 13 years; 47% male) underwent comprehensive 2‐dimensional Doppler transthoracic echocardiography and cardiac catheterization with transseptal measurement of left‐sided pressures. All studies were performed within 48 hours of one another.ResultsThe correlation of LVOT gradients from both methods performed at different times had a wide scatter with the 95% confidence limits of agreement being ± 84 mm Hg. For classifying patients as having severe LVOT obstruction on the basis of either method (<30 vs ≥ 30 mm Hg), discrepant results occurred in 21% of patients. To confirm the accuracy of Doppler measurements, 15 studies were performed with simultaneous measurement of LVOT gradient, which revealed a very strong correlation (r = 0.98, p < 0.0001) with 95% confidence limits of agreement ± 12 mm Hg.ConclusionsIn patients with HCM, LVOT gradient measurements are routinely obtained to characterize the severity of obstruction. However, these data demonstrate the marked variability of the LVOT obstruction, which must be considered when determining appropriate therapy in symptomatic patients. Copyright © 2009 Wiley Periodicals, Inc.
Metric spaces in NMR crystallography
Authors: Grant David M. , Halling Merrill D. 
Published: July 2009

AbstractThe anisotropic character of the chemical shift can be measured by experiments that provide shift tensor values and comparing these experimental components, obtained from microcrystalline powders, with 3D nuclear shielding tensor components, calculated with quantum chemistry, yields structural models of the analyzed molecules. The use of a metric tensor for evaluating the mean squared deviations, d2, between two or more tensors provides a statistical way to verify the molecular structure governing the theoretical shielding components. The sensitivity of the method is comparable with diffraction methods for the heavier organic atoms (i.e., C, O, N, etc.) but considerably better for the positions of H atoms. Thus, the method is especially powerful for H‐bond structure, the position of water molecules in biomolecular species, and other proton important structural features, etc. Unfortunately, the traditional Cartesian tensor components appear as reducible metric representations and lack the orthogonality of irreducible icosahedral and irreducible spherical tensors, both of which are also easy to normalize. Metrics give weighting factors that carry important statistical significance in a structure determination. Details of the mathematical analysis are presented and examples given to illustrate the reason nuclear magnetic resonance are rapidly assuming an important synergistic relationship with diffraction methods (X‐ray, neutron scattering, and high energy synchrotron irradiation). © 2009 Wiley Periodicals, Inc.Concepts Magn Reson Part A 34A: 217–237, 2009.
Trap design for insertable second‐nuclei radiofrequency coils for magnetic resonance imaging and spectroscopy
Authors: Dabirzadeh Arash , McDougall Mary Preston 
Published: July 2009

AbstractThe application of nuclear magnetic resonance spectroscopy in metabolic studies usually includes concurrent operation at two different frequencies to enable excitation and detection of two different nuclei. When using separate radiofrequency coils for the multinuclear excitation, coupling between the two coils has been shown to be a problem, resulting in resonance frequency shifting and reduced sensitivity of the 1H coil. Among the methods to reduce this coupling is the placement of an 1H trap on the second‐nuclei coil. This article presents the benefits of this method, specifically in this case for 31P imaging/spectroscopy, through modeling results, bench measurements, imaging, and spectra acquisition. The use of a resonant trap in conjunction with a modular design permitted the insertion of the phosphorus coil as an “add‐on” into multiple existing proton coils, suggesting particular applicability in the high‐field arena, where spectroscopy holds great promise, but where proton coil design complexity exists that is not easily re‐engineered for dual‐nuclei use. © 2009 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 35B: 121–132, 2009
A wrapped edge transverse gradient coil design for increased gradient homogeneity
Authors: Vegh Viktor , Tieng Quang M. , Brereton Ian M. , Galloway Graham J. 
Published: July 2009

AbstractA transverse gradient coil design is described for wire wound cylindrical applications. The proposed design is aimed for use as a fixed gradient coil or as an insertable gradient coil. Although we describe a transverse gradient coil for clinical MRI scanners, the principle could be applied for use in preclinical systems. The gradient coil wire wound return paths are altered to allow for the ends of the gradient coil to be wrapped into the transverse plane of the MRI system to reduce the effect of their contribution to the magnetic field within the FoV. In essence, this new configuration reduces the inductance of the coil by decreasing the primary path and return path interactions, and in addition, minimising field oscillations to reduce peripheral nerve stimulation. The proposed design produces a large FoV, low coil inductance and small high order harmonics contributing to improved gradient magnetic field linearity. The proposed concept is particularly aimed at short bore magnets, as the length of the gradient tube becomes the limiting factor in magnet system bore length. © 2009 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 35B: 139–152, 2009
A passive dual‐circulator based transmit/receive switch for use with reflection resonators in pulse electron paramagnetic resonance
Authors: Sundramoorthy Subramanian V. , Epel Boris , Mailer Colin , Halpern Howard J. 
Published: July 2009

AbstractTo protect the low‐noise amplifier (LNA) in the receive arm of a pulsed 250 MHz EPR bridge, it is necessary to install as much isolation as possible between the power exciting the spin system and the LNA when high power is present in the receive arm of the bridge, while allowing the voltage induced by the magnetization in the spin sample to be passed undistorted and undiminished to the LNA once power is reduced below the level that can cause LNA damage. We discuss a combination of techniques to accomplish this involving the power‐routing circulator in the bridge, a second circulator acting as an isolator with passive shunt PIN diodes immediately following the second circulator. The low resistance of the forward biased PIN diode passively generates an impedance mismatch at the second circulator output port during the high‐power excitation pulse and resonator ring down. The mismatch reflects the high power to the remaining port of the second circulator, dumping it into a system impedance matched load. Only when the power diminishes below the diode conduction threshold, the resistance of the PIN diode will rise to a value much higher than the system impedance. This brings the device into conduction mode. We find that the present design passively limits the output power to 14 dBm independent of the input power. For high‐input power levels, the isolation may exceed 60 dB. This level of isolation is sufficient to fully protect the LNA of a pulse EPR bridge. © 2009 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 35B: 133–138, 2009
Electrochemical One‐Electron Oxidation of Low‐Generation Polyamidoamine‐Type Dendrimers with a 1,4‐Phenylenediamine Core
Authors: Hammerich Ole , Hansen Thomas , Thorvildsen Asbjørn , Christensen Jørn B. 
Published: July 2009

AbstractA series of polyamidoamine (PAMAM)‐type dendrimers with a 1,4‐phenylenediamine (PD) core is prepared from PD by procedures including Michael addition of methyl acrylate followed by aminolysis with 1,2‐ethanediamine. Their one‐electron oxidation potentials are determined by differential pulse voltammetry (DPV) in methanol, acetonitrile, dichloromethane, and dimethyl sulfoxide. The dendrimers are more difficult to oxidize than N,N,N′,N′‐tetramethyl‐p‐phenylenediamine (TMePD). The oxidation potentials decrease with increasing dendrimer generation up to G0.5, after which the potential is essentially constant up to G2.0. The structures of both the neutral species and the radical cations are studied by DFT calculations at the B3LYP/6‐31G(d,p) level of theory, which include a series of simple PDs for comparison. The data show that the structural arrangement close to the PD core is similar to that of N,N,N′,N′‐tetra‐n‐alkyl‐p‐phenylenediamines, including a planar arrangement of the atoms linked to the two PD nitrogen atoms. Thus, the effect of chain size on the oxidation potential appears to be caused primarily by a simple electronic effect. The calculations indicate considerable reorientation of the dendrimer side chains on oxidation, presumably caused by interactions between the positive charge centered at the core and the neighboring ester or amide dipoles. The relative ease of oxidation of TMePD and the lowest members of the series of the dendrimers can be reproduced theoretically only when solvation was included in the calculations. The DPV peak heights vary approximately as predicted from the Stokes–Einstein–Sutherland equation, but the variation of the relative effective radii with the size of the dendrimer is much larger than predicted from the radii obtained by the DFT calculations, that is, the dendrimers exist in solution mainly as aggregates.