bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Applying Continuous Catalytic Processes to Improved Syntheses of Selected Fine Chemicals and Pharmaceutical Intermediates
Authors: Yoon Jaeyon 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Photodeconjugation: Highly Stereoselective Synthesis of α‐Fluorocarboxylic Derivatives
Authors: Bargiggia Frederic , Dos Sylvia , Piva Olivier 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Methodologies for Carbo‐Substituted Conjugated Dienes
Authors: Vasil'ev A. A. , Serebryakov E. P. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbon—Carbon Bond Formation Based on Alkenylphosphonates
Authors: Nagaoka Yasuo 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Modification of Morphine Dependence under Chronic Pain and Its Mechanism
Authors: Suzuki Tsutomu 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From Lobry de Bruyn to Enzyme‐Catalyzed Ammonia Channelling: Molecular Studies of D‐Glucosamine‐6P Synthase
Authors: Teplyakov Alexey , Leriche Caroline , Obmolova Galya , Badet Bernard , Badet‐Denisot Marie‐Ange 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Oxylipin Chemistry of Attraction and Defense in Brown Algae and Diatoms
Authors: Pohnert Georg , Boland Wilhelm 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Computing Heteroatom‐Rich Five‐ and Six‐Membered Ring Systems
Authors: Rauhut Guntram 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: MR Spectroscopy Quantitation: A Review of Time‐Domain Methods
Authors: Vanhamme Leentie , Sundin Tomas , Van Hecke Paul , Van Huffel Sabine 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Updated Available Solvent Extraction Technologies
Authors: Diaz G. , Martin D. , Frias C. , Perez O. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Bindemittelfreie ZSM‐5‐Formkörper auf Basis von porösen Gläsern durch In‐situ‐Kristallisation: Herstellung, Eigenschaften und katalytische Testung
Authors: Rauscher M. , Schwab A. , Schwieger W. , Rauscher M. 
Published: May 2010

AbstractDer Zeolith‐Typ ZSM‐5 wird als funktionale Komponente für Katalysatoren in der Technik breit verwendet. ZSM‐5‐haltige Katalysatoren zeichnen sich durch die definierten Porengrößen im Bereich von ca. 0,6 nm, das spezielle Hohlraumsystem mit sich kreuzenden Kanälen und ihre auf Grund des variablen Si/Al‐Verhältnises in weiten Bereichen variabel einstellbare Zahl der aktiven Zentren aus. Bei der Formgebung müssen Größe, Form und Geometrie der Katalysatorkörper sowohl auf die Reaktion als auch auf den Reaktor abgestimmt sein. Die In‐situ‐Kristallisation auf einem Träger ist ein relativ junges Formgebungsverfahren. Die in der technischen Katalyse wichtigen Eigenschaften von bindemittelfreien ZSM‐5‐Zeolith‐Formkörpern, welche durch In‐situ‐Kristallisation erzeugt wurden, werden anhand des Modellzeolith ZSM‐5 (MFI‐Typ) beschrieben. Insbesondere die mechanische Stabilität sowie die katalytischen Eigenschaften dieser Zeolith‐Formkörper werden im Vergleich mit Literaturdaten und einem bindemittelfrei verpressten technischen Zeolithpulver diskutiert.
Inferences in generalized linear longitudinal mixed models
Authors: Sutradhar Brajendra C. 
Published: May 2010

AbstractWithout realizing the fact that the time‐dependent covariates corresponding to the repeated discrete responses under a generalized linear longitudinal model (GLLM) cause non‐stationary (time dependent) correlations for the repeated responses, many existing studies use a stationary (either “working” or true) correlation structure to develop certain estimating equations for the regression effects involved in the model. By constructing suitable non‐stationary correlation structures both for longitudinal count and binary data, this article first demonstrates that the stationary correlations based estimation approaches may yield inefficient regression estimates. For efficient estimation, the article then suggests a true non‐stationary correlation structure based generalized quasi‐likelihood (GQL) estimation approach, where non‐stationary correlation structure is identified by exploiting the estimated lag correlations of the responses. A generalization of the GLLM to the familial‐longitudinal set up both for count and binary data is also discussed, where the data exhibit familial as well as non‐stationary longitudinal correlations, the familial correlations among the responses of the family members are being generated through a random common family effect. The GQL estimating equations are provided for the estimation of the regression and the variance component parameters of this generalized linear longitudinal mixed model (GLLMM), whereas the longitudinal correlations are estimated by solving suitable moment estimating equations. The Canadian Journal of Statistics 38: 174–196; 2010 © 2010 Statistical Society of Canada
On quasi‐likelihood estimation for branching processes with immigration
Authors: Sutradhar Brajendra , Oyet Alwell J. , Gadag Veeresh G. 
Published: May 2010

AbstractIn the theory of estimation for branching processes it is well known that, in the super‐critical case, the so‐called conditional least‐squares and the conditional weighted least‐squares methods may not yield unbiased and hence consistent estimates for the mean parameters of the offspring and immigration distributions. In this paper, the authors propose a new conditional quasi‐likelihood method in the context of negative binomial offspring and immigration distributions that provides mean estimates with smaller mean squared errors in the super‐critical case as compared to the previous approaches. Further, they simplify the conditional quasi‐likelihood estimating equations both for the mean and the variance parameters under a special model with binary offspring distribution appropriate for a controlled population. It is also demonstrated empirically that a reasonable estimate for the variance or overdispersion parameter requires that the data be collected over a long period of time. The Canadian Journal of Statistics 38: 290–313; 2010 © 2010 Statistical Society of Canada
Mass spectrometrical analysis of the mitochondrial carrier Aralar1 from mouse hippocampus
Authors: Heo Seok , Kang Sung Ung , Oehler Rudolf , Pollak Arnold , Lubec Gert 
Published: May 2010

AbstractAralar1 is a mitochondrial aspartate/glutamate carrier and a key component of the malate–aspartate NADH shuttle system. An analytical approach to obtain high sequence coverage is important to predict conformation, identify splice variants and binding partners or generate specific antibodies. Moreover, a method allowing determination of Aralar1 from brain samples is a prerequisite for evaluating a biological role. Sucrose gradient ultracentrifugation was applied to enrich native membrane protein fractions and these were run on blue‐native PAGE, followed by multidimensional gel electrophoresis. Spots from the third‐dimensional gel electrophoresis were in‐gel digested with trypsin, chymotrypsin and subtilisin. Subsequently, peptides were analyzed by nano‐ESI‐LC‐MS/MS using collision‐induced dissociation and electron transfer dissociation modes. Modiro™ v1.1 along with Mascot v2.2 software was used for data handling. Aralar1 could be clearly separated, unambiguously identified and characterized from protein extracts of mouse hippocampus by the use of the multidimensional gel electrophoretic steps. The combined sequence coverage of Aralar1 from trypsin, chymotrypsin and subtilisin digestions was 99.85%. The results provide the basis for future studies of Aralar1 at the protein chemical rather than at the immunochemical level in the brain and thus challenge and enable determination of Aralar1 levels required for understanding biological functions in health and disease.
Comparison of contrast‐enhanced MR angiography to intraarterial digital subtraction angiography for evaluation of peripheral arterial occlusive disease: Results of a phase III multicenter trial
Authors: Bui Bao T. , Miller Stephan , Mildenberger Peter , Sam Albert , Sheng Rubin 
Published: May 2010

AbstractPurposeTo evaluate the efficacy and safety of 0.1 mmol/kg gadodiamide administration for contrast‐enhanced magnetic resonance angiography (CE‐MRA) in detecting hemodynamically relevant main stenosis (ie, ≥50% or occlusion) of aortoiliac arteries.Materials and MethodsIn a multicenter, phase 3, controlled study, patients with suspected or proven peripheral arterial occlusive disease (PAOD) underwent CE‐MRA with administration of gadodiamide. Intraarterial digital subtraction angiography (IA‐DSA) was used as the reference. The study was approved by all Institutional Review Boards or Institutional Ethic Committees prior to commencement of patient recruitment and written informed consent was obtained from all patients.ResultsIndependent readers rated 25%–45% of CE‐MRA images as excellent compared with 0.3%–6% of noncontrast MRA images. Mean imaging acquisition time for CE‐MRA was <1 minute (0.7 ± 1.9 minutes) versus 10 minutes (10.8 ± 3.0) for noncontrast MRA. Sensitivity, specificity, and accuracy of CE‐MRA were superior compared with those of noncontrast MRA in detecting significant arterial stenoses. Compared with IA‐DSA, the sensitivity of CE‐MRA ranged from 80%–88% and the specificity from 73% to 92% for the three blinded readers, at the patient level.ConclusionDiagnostic results with CE‐MRA were superior and more consistent compared with noncontrast MRA for detecting hemodynamically relevant main stenoses in patients with suspected or proven PAOD and compared favorably with IA‐DSA as a reference standard. J. Magn. Reson. Imaging 2010;31:1402–1410. © 2010 Wiley‐Liss, Inc.
Quantification of the magnetic resonance signal response to dynamic (C)O2‐enhanced imaging in the brain at 3 T: R*2 BOLD vs. balanced SSFP
Authors: Remmele Stefanie , Dahnke Hannes , Flacke Sebastian , Soehle Martin , Wenningmann Ingobert , Kovacs Attila , Träber Frank , Müller Andreas , Willinek Winfried A. , König Roy , Clusmann Hans , Gieseke Jürgen , Schild Hans H. , Mürtz Petra 
Published: May 2010

AbstractPurpose:To compare two magnetic resonance (MR) contrast mechanisms, R*2 BOLD and balanced SSFP, for the dynamic monitoring of the cerebral response to (C)O2 respiratory challenges.Materials and Methods:Carbogen and CO2‐enriched air were delivered to 9 healthy volunteers and 1 glioblastoma patient. The cerebral response was recorded by two‐dimensional (2D) dynamic multi‐gradient‐echo and passband‐balanced steady‐state free precession (bSSFP) sequences, and local changes of R*2 and signal intensity were investigated. Detection sensitivity was analyzed by statistical tests. An exponential signal model was fitted to the global response function delivered by each sequence, enabling quantitative comparison of the amplitude and temporal behavior.Results:The bSSFP signal changes during carbogen and CO2/air inhalation were lower compared with R*2 BOLD (ca. 5% as opposed to 8–13%). The blood‐oxygen‐level‐dependent (BOLD) response amplitude enabled differentiation between carbogen and CO2/air by a factor of 1.4–1.6, in contrast to bSSFP, where differentiation was not possible. Furthermore, motion robustness and detection sensitivity were higher for R*2 BOLD.Conclusion:Both contrast mechanisms are well suited to dynamic (C)O2‐enhanced MR imaging, although the R*2 BOLD mechanism was demonstrated to be superior in several respects for the chosen application. This study suggests that the R*2 BOLD and bSSFP‐response characteristics are related to different physiologic mechanisms. J. Magn. Reson. Imaging 2010;31:1300–1310. © 2010 Wiley‐Liss, Inc.
Robust, unbiased general linear model estimation of phMRI signal amplitude in the presence of variation in the temporal response profile
Authors: Pendse Gautam V. , Schwarz Adam J. , Baumgartner Richard , Coimbra Alexandre , Upadhyay Jaymin , Borsook David , Becerra Lino 
Published: May 2010

AbstractPurpose:To determine a simple yet robust method to generate parsimonious design matrices that accurately estimate the “pharmacological MRI” (phMRI) response amplitude in the presence of both confounding signals and variability in temporal profile. Variability in the temporal response profile of phMRI time series data is often observed. If not properly accounted for, this variation can result in inaccurate and unevenly biased signal amplitude estimates when modeled within a general linear model (GLM) framework.Materials and Methods:The approach uses a low‐rank singular value decomposition (SVD) approximation to a set of vectors capturing anticipated variations of no interest around the signal model to generate additional regressors for the design matrix. The method is demonstrated for both plateau and bolus type phMRI response profiles in the presence of variation in signal onset and/or shape, and applied to an in vivo blood oxygenation level‐dependent (BOLD) phMRI study of buprenorphine in healthy human subjects.Results:In general, 2–3 additional regressors, capturing >75% of the anticipated variance, resulted in robust and unbiased signal amplitude estimates in the presence of substantial variability.Conclusion:This method provides a simple and flexible means to provide robust phMRI amplitude estimates within a GLM framework. J. Magn. Reson. Imaging 2010;31:1445–1457. © 2010 Wiley‐Liss, Inc.
Quantification of superparamagnetic iron oxide‐mediated signal intensity change in patients with liver cirrhosis using T2 and T2* mapping: A preliminary report
Authors: Chung Yong Eun , Park Mi‐Suk , Kim Myoung Soo , Kim Eunju , Park Jaeseok , Song Ho‐Taek , Choi Jin Young , Kim Myeong‐Jin , Kim Ki Whang 
Published: May 2010

AbstractPurpose:To quantify the accumulation of superparamagnetic iron oxide (SPIO) in patients with and without liver cirrhosis using T2 and T2* mapping.Materials and Methods:We enrolled 10 patients without liver cirrhosis and 30 patients with liver cirrhosis (Child‐Pugh class A, n = 18; and B/C, n = 12). T2 and T2* mapping were performed before and after SPIO administration. The reductions in T2 (ΔT2) and T2* (ΔT2*) after SPIO administration were compared between the control and liver cirrhosis groups and the control, Child‐Pugh A, and Child Pugh B/C groups.Results:There were significant differences in ΔT2 (22.2 ± 4.4 and 15.1 ± 7.0) and ΔT2* values (24.3 ± 3.3 and 16.8 ± 8.1) (P = 0.005 and P < 0.001) between the control and the liver cirrhosis groups. There was a significant difference in the ΔT2* between the Child‐Pugh A and Child‐Pugh B/C groups (P < 0.001) and in the ΔT2 and ΔT2* between the control and Child‐Pugh B/C groups (P = 0.018 and P < 0.001).Conclusion:ΔT2 and ΔT2* are significantly larger in patients without liver cirrhosis than those with liver cirrhosis. ΔT2* is also significantly larger in Child‐Pugh class A patients than those in Child‐Pugh B/C. J. Magn. Reson. Imaging 2010;31:1379–1386. © 2010 Wiley‐Liss, Inc.
Eccentric target sign in cerebral toxoplasmosis: Neuropathological correlate to the imaging feature
Authors: Kumar G.G. Sharath , Mahadevan A. , Guruprasad A.S. , Kovoor Jerry M.E. , Satishchandra P. , Nath Avindra , Ranga Udaykumar , Shankar S.K. 
Published: May 2010

AbstractCerebral toxoplasmosis remains one of the most common focal brain lesions in patients with acquired immune deficiency syndrome (AIDS). Diagnosis is a challenge because on cranial imaging it closely mimics central nervous system lymphoma, primary and metastatic central nervous system (CNS) tumors, or other intracranial infections like tuberculoma or abscesses. A magnetic resonance imaging (MRI) feature on postcontrast T1‐weighted sequences considered pathognomonic of toxoplasmosis is the “eccentric target sign.” The pathological correlate of this imaging sign has been speculative. Herein we correlate the underlying histopathology to the MR feature of eccentric target sign in a patient with autopsy‐proven HIV/AIDS‐related cerebral toxoplasmosis. The central enhancing core of the target seen on MRI was produced by a leash of inflamed vessels extending down the length of the sulcus that was surrounded by concentric zones of necrosis and a wall composed of histiocytes and proliferating blood vessels, with impaired permeability producing the peripheral enhancing rim. J. Magn. Reson. Imaging 2010;31:1469–1472. © 2010 Wiley‐Liss, Inc.
T2 determination of the J‐coupled methyl protons of lipids: In vivo ilustration with tibial bone marrow at 3 T
Authors: Yahya Atiyah , Fallone B. Gino 
Published: May 2010

AbstractPurpose:To demonstrate how J‐coupling modulations of the CH3 lipid resonance can be minimized enabling a representative T2 to be measured.Materials and Methods:Experiments were conducted on canola oil and in vivo on tibial bone marrow of four volunteers at 3 T. The T2 of the CH2 protons was measured with a standard point resolved spectroscopy (PRESS) sequence, whereas the T2 of the CH3 protons was determined with a PRESS sequence composed of narrow bandwidth refocusing pulses designed to exploit the chemical shift displacement effect and rewind the J‐coupling evolution of the CH3 protons in the desired voxel. Spectra were acquired at five echo times.Results:The narrow bandwidth PRESS sequence rewound the J‐evolution of the CH3 protons resulting in a T2 curve that was well described by a monoexponential function. The mean T2 of the bone marrow CH3 protons was calculated to be 132.6 msec. The mean T2 of the bone marrow CH2 protons was estimated with a regular PRESS sequence to be 88.0 msec. The mean CH2:CH3 tibial bone marrow composition was estimated to be 12.0:1.Conclusion:The presented technique permits the T2 of the methyl protons of lipids to be determined with more accuracy by minimizing contributions from J‐coupling. J. Magn. Reson. Imaging 2010;31:1514–1521. © 2010 Wiley‐Liss, Inc.
Detection of uncommon rotavirus a strains P[8]G8 and P[4]G8 in the city of Rio de Janeiro, 2002
Authors: Gómez M.M. , Volotão E.M. , de Mendonça M.C. Lima , Tort L.F.L. , da Silva M.F.M. , Leite J.P.G. 
Published: May 2010

AbstractGroup A rotaviruses (RV‐A) are the major cause of gastroenteritis in infants and young children around the world. Each year RV‐A causes approximately 11 million episodes of severe diarrhea, with an estimated of 611,000 deaths. Epidemiologic surveys have identified P[8]G1, P[4]G2, P[8]G3, P[8]G4, and P[8]G9 as the most common global genotypes associated with diarrhea in children up to 5‐year old. Surveillance studies and documentation of RV‐A G and P genotypes is necessary for a comprehensive evaluation of the evolution of new strains, and assessing the capability of vaccines to provide heterotypic protection. It is known that reassortments are the driving force for genetic diversity through sudden changes in RV‐A genome. In this study, we identified two unusual P/G combinations, P[8]G8 and P[4]G8, occurring in Rio de Janeiro during 2002. Results obtained in this study suggest that P[8]G8 RV‐A strain originated from a reassortment event that occurred between RV‐A P[4]G8 and P[8]G9 strains circulating in Rio de Janeiro in the same year. G8 strains identified in this study, as well as G8 strains detected in Recife by Montenegro et al. [Montenegro et al. (2007) J Med Virol 79: 335–340], showed a close genetic relationship with strains from Africa, where this genotype have become prevalent. J. Med. Virol. 82: 1272–1275, 2010. © 2010 Wiley‐Liss, Inc.
Case report: Cure of chronic infection with hepatitis C virus after 6 weeks of peg‐interferon and ribavirin in a patient co‐infected with HIV
Authors: Rachline Anne , Palmer Pierre , Simon François , Molina Jean‐Michel 
Published: May 2010

AbstractThe recommended treatment duration of chronic hepatitis C virus (HCV) in patients infected with human immunodeficiency virus (HIV) is 48 weeks. This report describes a patient co‐infected with HCV genotype 2 and HIV who discontinued HCV therapy after 6 weeks because of adverse events and had a sustained virologic response. J. Med. Virol. 82:1150–1151, 2010. © 2010 Wiley‐Liss, Inc.