bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heterotopic triplet pregnancy: report of a patient with remnant tubal ectopic and intrauterine twin pregnancy after frozen‐thawed embryo transfer
Authors: Okamura Yoshinori , Arakane Futoshi , Nagayoshi‐Taura Yumiko , Honda Ritsuo , Ohba Takashi , Katabuchi Hidetaka 
Published: June 2011

AbstractA case of heterotopic triplet pregnancy after frozen‐thawed embryo transfer is presented. The patient conceived after transfer of three frozen‐thawed embryos at a fertility clinic where she had previously undergone laparoscopic left salpingectomy due to pyosalpinx. Approximately 4 weeks after the embryo transfer, she presented with a complaint of abnormal genital bleeding and was diagnosed by ultrasound as having a dichorionic twin pregnancy. One week later, she was referred to our hospital because of lower abdominal pain. Hematoperitoneum was suspected based on findings of low blood pressure and tachycardia. Diagnostic emergent laparoscopy demonstrated an ectopic pregnancy in the remnant isthmic portion of the left tube. Laparoscopic excision of the remnant fallopian tube was performed, but the procedure resulted in early‐pregnancy loss of one of the twins. The risk of heterotopic pregnancy is not small under assisted reproductive technology. Attention should be paid to the risk of tubal pregnancy after transferring more than two embryos or controlled ovarian hyperstimulation, even after salpingectomy has been performed.
The African Cultural Astronomy Project
Authors: Urama Johnson O. , Holbrook Jarita C. 
Published: June 2011

AbstractIndigenous, endogenous, traditional, or cultural astronomy focuses on the many ways that people and cultures interact with celestial bodies. In most parts of Africa, there is very little or no awareness about modern astronomy. However, like ancient people everywhere, Africans wondered at the sky and struggled to make sense of it. The African Cultural Astronomy Project aims to unearth the body of traditional knowledge of astronomy possessed by peoples of the different ethnic groups in Africa and to consider scientific interpretations when appropriate for cosmogonies and ancient astronomical practices. Regardless of scientific validity, every scientist can relate to the process of making observations and creating theoretical mechanisms for explaining what is observed. Through linking the traditional and the scientific, it is believed that this would be used to create awareness and interest in astronomy in most parts of Africa. This paper discusses the vision, challenges and prospects of the African Cultural Astronomy Project in her quest to popularize astronomy in Africa.
The Cosmology of Edgar Allan Poe
Authors: Cappi Alberto 
Published: June 2011

AbstractEureka is a “prose poem” published in 1848, where Edgar Allan Poe presents his original cosmology. While starting from metaphysical assumptions, Poe develops an evolving Newtonian model of the Universe which has many and non casual analogies with modern cosmology. Poe was well informed about astronomical and physical discoveries, and he was influenced by both contemporary science and ancient ideas. For these reasons, Eureka is a unique synthesis of metaphysics, art and science.
Astronomical activities with disabled people
Authors: Ortiz-Gil Amelia , Blay Pere , Calvente A. Teresa Gallego , Gómez Miquel , Guirado José Carlos , Lanzara Mariana , Núñez Silvia Martínez 
Published: June 2011

AbstractAs we celebrate the International Year of Astronomy, we have been working on four different projects with the goal of making astronomy more accessible to people with special needs. These projects are 1) an astronomy book and web site for blind people, 2) an open source software for people with motor disabilities, 3) a planetarium program for the visually impaired and 4) educational material for intellectually disabled people.
The UNESCO Thematic Initiative on Astronomy and World Heritage
Authors: Sidorenko Anna P. 
Published: June 2011

AbstractProperties with a relationship to science are amongst the least represented on the UNESCO World Heritage List and the values of these properties, located in all the regions of the world, are not sufficiently recognised. The UNESCO and IAU encourage the States Parties to the World Heritage Convention to actively participate in the development and implementation of the Thematic Initiative “Astronomy and World Heritage” aiming to provide an opportunity to identify the properties connected with astronomy and for keeping their memory alive and preserving them from progressive deterioration, through the inscription of the most representative properties on the World Heritage List.
Virtual Acoustic Space: Space perception for the blind
Authors: Rodríguez-Ramos Luis F. 
Published: June 2011

AbstractThis R&D project implements a new way of perception of the three-dimensional surrounding space, based exclusively in sounds and thus especially useful for the blind. The innate capability of locating sounds, the externalization of sounds played with headphones and the machine capture of the 3D environment are the technological pillars used for this purpose. They are analysed and a summary of their main requirements are presented. A number of laboratory facilities and portable prototypes are described, together with their main characteristics.
Astronomy and political theory
Authors: Campion Nicholas 
Published: June 2011

AbstractThis paper will argue that astronomical models have long been applied to political theory, from the use of the Sun as a symbol of the emperor in Rome to the application of Copernican theory to the needs of absolute monarchy. We will begin with consideration of astral divination (the use of astronomy to ascertain divine intentions) in the ancient Near East. Particular attention will be paid to the use of Newton's discovery that the universe operates according to a single set of laws in order to support concepts of political quality and eighteenth century Natural Rights theory. We will conclude with consideration of arguments that the discovery of the expanding, multi-galaxy universe, stimulated political uncertainty in the 1930s, and that photographs of the Earth from Apollo spacecraft encouraged concepts of the ‘global village’.
Teaching astronomy and astrophysics with Hands-On-Universe and SalsaJ: stars, planets, exoplanets and dark matter
Authors: Faye Suzanne , Faye Michel 
Published: June 2011

AbstractHow can teachers and researchers contribute to a new world-wide way to teach astronomy? The Hands-On-Universe group proposes multi-media tools, from remote telescopes to image processing, inspired by the most recent research activities in astronomy and astrophysics. Teachers and students can learn, in a quantitative way, to analyse images and spectra using free data sets and softwares available at the website www.eu-hou.org.
Ancient Chinese constellations
Authors: Xu Junjun 
Published: June 2011

AbstractChina, a country with a long history and a specific culture, has also a long and specific astronomy. Ancient Chinese astronomers observed the stars, named and distributed them into constellations in a very specific way, which is quite different from the current one. Around the Zodiac, stars are divided into four big regions corresponding with the four orientations, and each is related to a totem, either the Azure Dragon, the Vermilion Bird, the White Tiger or the Murky Warrior. We present a general pattern of the ancient Chinese constellations, including the four totems, their stars and their names.
A unique astronomical heritage place: the 28 May 585 BCE solar eclipse
Authors: Özel Mehmet Emin 
Published: June 2011

AbstractProbably the only reliably recorded solar eclipse event during a day-time war is the 28 May 585 BCE event, famous also for several other reasons. It has a credible written record, mentioned by the ancient historian Heredotus and his History notes that the eclipse was predicted by Thales of Miletos (the Ionian capital city in Western Anatolia). The location of the war between Lydians and the Medes is now firmly located as the plain in front of ancient city of Pteria, the Anatolian capital of the Medes. The historical record mentions that the war stopped and a peace treaty was signed, with the wedding of a prince and a princess from rival kings. All these features make the event and place an excellent candidate for a World Astronomical Heritage site to be preserved.
The ancient cultural framework of astronomy in Ukraine
Authors: Vavilova Iryna B. , Artemenko Tetyna G. 
Published: June 2011

AbstractWe describe and discuss most interesting archaeological findings related to old astronomy in Ukraine. Among them are the mammoth tusk fragments (Gontsy and Kiev-Kirilivska settlements) and the famous Mezin bracelets (Mezin settlement), where possible calendar patterns based on the lunar cycles are engraved with fine accuracy, as well as a possible stellar map on the mammoth shoulder bone (Chocurcha-2 settlement).
The rôle of planetaria: The Library of Alexandria Planetarium Science Center
Authors: El-Mitaky Hoda S. 
Published: June 2011

AbstractIn ancient times the stars and the Moon were humans' only guide to cross the seas and explore the depths of the deserts. With the use of modern technological gadgets, and the increasingly light pollution, citizens of the world stopped looking at the heavens. How can planetaria play a rôle in reviving public interest in astronomy? How can the beauty of astronomy play a rôle in luring the youth to pursue a career in science? How can astronomy play a rôle in raising public awareness about preserving the environment? Moreover, how can astronomy play a rôle in the dialogue among civilisations?
The Sun and solar eclipses in traditional Romanian ornamental patterns
Authors: Olenici Dimitrie , Olenici Maria 
Published: June 2011

AbstractVarious ornamental shapes, such as the wheel, the rhombus, the broken cross, and the radiant triangle, which can be seen on popular costumes, domestic objects as well as in architecture, represent solar symbols with a clear apotropaic function whose origins may be detected on the Neolithic clay plates from Jevdet Nasr (Iraq), Knosos (Greece) and Tartaria (Romania). In the North-East of Romania the occurrence of such motifs is extremely frequent especially in traditional architecture. The Triple-Rayed Sun intersected by two lateral arcs is a remarkable adornment of this kind that seems to suggest the representation of an eclipse.
Science and journalism: friend or foe?
Authors: Mosoia Cătălin 
Published: June 2011

AbstractA journalist's view on science and journalism. The presentation is based on personal experience gained over the past few years as editor of the minute of science broadcasted at Radio Europa FM, Bucharest, Romania, and as editor and writer for the Romanian electronic science newspaper Ziarul stiintelor. Is it possible to have science with or without journalism? Who is waiting for whom, science or journalism? Is astronomy more attractive to the public than other disciplines? Can it be used as a growing factor for the public understanding of science?
Astronomy, space science and geopolitics
Authors: Courvoisier Thierry J.-L. 
Published: June 2011

AbstractAstronomy has played a major part in the development of civilisations, not only through conceptual developments, but most importantly through the very practical gains obtained through the observation of Sun, Moon planets and stars. Space sciences, including astronomy, have also played a major rôle in the development of modern societies, as an engine for most subsequent space technology developments. Present trends tend to decrease the rôle of science in space development. This trend should be reversed to give modern “societies” their independence in space-related matters that permeate the lives of all inhabitants of the Earth.
The history of the International Astronomy Olympiad
Authors: Gavrilov Michael G. , Salnikov Igor V. , Vaesterberg Anders R. 
Published: June 2011

AbstractThe International Astronomy Olympiad (IAO) was founded in the 1990s as an annual scientific educating event for students of the junior high school classes. Starting from 4 teams at the 1st event in 1996 the Olympiad includes more than 20 countries nowadays. The style of the problems of IAO is aimed at developing the imagination, creativity and independent thinking. They stimulate the students to recognize the problem independently, to choose a model, to make necessary suppositions, estimations, to conduct multiway calculations or logic operations. The Asian-Pacific Astronomy Olympiad was founded as a “daughter” (“affiliated”) olympiad in system of the International Astronomy Olympiad in 2005.
An ear turned to “The Cosmos”: 50 projects to discover the universe
Authors: del Puerto Carmen 
Published: June 2011

AbstractIn 1609, as Galileo pointed the sky with a telescope, he observed Jupiter's satellites and changed our vision of the universe. Four hundred years later, we celebrate this event all over the world, and also in the Canaries. 2009, the International Year of Astronomy, is a very special year for the Science and Cosmos Museum (Museo de la Ciencia y el Cosmos). This was the first museum in Spain supported by a public entity, The Local Government of Tenerife (Cabildo de Tenerife), through its Autonomous Council of Museums (Organismo Autónomo de Museos y Centros), and a research centre, the Instituto de Astrofísica de Canarias. Fifteen years later, this museum, which receives 50,000 visitors a year, celebrates the International Year of Astronomy with fifty projects described in this paper.
The outreach plan around the first science with the Gran Telescopio CANARIAS (GTC)
Authors: Zelmanovitch Natalia Ruiz 
Published: June 2011

Abstract2009 is important for Astronomy in Spain, not just because of the celebration of the International Year of Astronomy, but because of the beginning of the Gran Telescopio CANARIAS's operation. The Project ‘Consolider-Ingenio 2010: First Science with the GTC’, is a project funded by the Spanish Ministry of Science & Innovation (MICINN). For this project, it is fundamental that the GTC, a complex and expensive installation, produces science from the very beginning. One of the project objectives is Public Outreach and, in this paper we explain the outreach and education plans around the first science with the GTC.
Paired-end RAD-seq forde novoassembly and marker design without available reference
Authors: Willing Eva-Maria , Hoffmann Margarete , Klein Juliane D. , Weigel Detlef , Dreyer Christine 
Published: June 2011

AbstractMotivation: Next-generation sequencing technologies have facilitated the study of organisms on a genome-wide scale. A recent method called restriction site associated DNA sequencing (RAD-seq) allows to sample sequence information at reduced complexity across a target genome using the Illumina platform. Single-end RAD-seq has proven to provide a large number of informative genetic markers in reference as well as non-reference organisms.Results: Here, we present a method for de novo assembly of paired-end RAD-seq data in order to produce extended contigs flanking a restriction site. We were able to reconstruct one-tenth of the guppy genome represented by 200–500 bp contigs associated to EcoRI recognition sites. In addition, these contigs were used as reference allowing the detection of thousands of new polymorphic markers that are informative for mapping and population genetic studies in the guppy.Availability: A perl and C++ implementation of the method demonstrated in this article is available under http://guppy.weigelworld.org/weigeldatabases/radMarkers/ as package RApiD.Contact: christine.dreyer@tuebingen.mpg.deSupplementary Information: Supplementary data are available at Bioinformatics online.
Interactive Exploration of Protein Cavities
Authors: Krone M. , Falk M. , Rehm S. , Pleiss J. , Ertl T. 
Published: June 2011

AbstractWe present a novel application for the interactive exploration of cavities within proteins in dynamic data sets. Inside a protein, cavities can often be found close to the active center. Therefore, when analyzing a molecular dynamics simulation trajectory it is of great interest to find these cavities and determine if such a cavity opens up to the environment, making the binding site accessible to the surrounding substrate. Our user‐driven approach enables expert users to select a certain cavity and track its evolution over time. The user is supported by different visualizations of the extracted cavity to facilitate the analysis. The boundary of the protein and its cavities is obtained by means of volume ray casting, where the volume is computed in real‐time for each frame, therefore allowing the examination of time‐dependent data sets. A fast, partial segmentation of the volume is applied to obtain the selected cavity and trace it over time. Domain experts found our method useful when they applied it exemplarily on two trajectories of lipases from Rhizomucor miehei and Candida antarctica. In both data sets cavities near the active center were easily identified and tracked over time until they reached the surface and formed an open substrate channel.
Visual Recommendations for Network Navigation
Authors: Crnovrsanin Tarik , Liao Isaac , Wu Yingcai , Ma Kwan‐Liu 
Published: June 2011

AbstractUnderstanding large, complex networks is important for many critical tasks, including decision making, process optimization, and threat detection. Existing network analysis tools often lack intuitive interfaces to support the exploration of large scale data. We present a visual recommendation system to help guide users during navigation of network data. Collaborative filtering, similarity metrics, and relative importance are used to generate recommendations of potentially significant nodes for users to explore. In addition, graph layout and node visibility are adjusted in real‐time to accommodate recommendation display and to reduce visual clutter. Case studies are presented to show how our design can improve network exploration.
Demonstrating freedom from equine influenza in New South Wales, Australia, following the 2007 outbreak
Authors: Sergeant ESG , Wilson G 
Published: June 2011

ObjectiveTo quantify the probability of freedom from equine influenza (EI) in New South Wales (NSW), Australia, based on analysis of polymerase chain reaction (PCR) testing.Methods  Testing in the infected areas of NSW during the period 1 January to 30 April 2008.Results  Data from the random survey were collated and analysed to provide estimates of the probability of detecting EI if it was present at a prevalence ranging from 0.01% to 0.5%. The sensitivity estimates were then combined with a prior estimate of the probability of freedom in a simulation model, to estimate the posterior probability of freedom from EI (given the negative results of the random survey).Conclusions  The very large volume of PCR tests performed provided a very high level of confidence that EI had been successfully eradicated from NSW.
Cross-Shelf and Out-of-Bay Transport Driven by an Open-Ocean Current
Authors: Zhang Yu , Pedlosky Joseph , Flierl Glenn R. 
Published: June 2011

Abstract
This paper studies the interaction of an Antarctic Circumpolar Current (ACC)–like wind-driven channel flow with a continental slope and a flat-bottomed bay-shaped shelf near the channel’s southern boundary. Interaction between the model ACC and the topography in the second layer induces local changes of the potential vorticity (PV) flux, which further causes the formation of a first-layer PV front near the base of the topography. Located between the ACC and the first-layer slope, the newly formed PV front is constantly perturbed by the ACC and in turn forces the first-layer slope with its own variability in an intermittent but persistent way. The volume transport of the slope water across the first-layer slope edge is mostly directly driven by eddies and meanders of the new front, and its magnitude is similar to the maximum Ekman transport in the channel. Near the bay’s opening, the effect of the topographic waves, excited by offshore variability, dominates the cross-isobath exchange and induces a mean clockwise shelf circulation. The waves’ propagation is only toward the west and tends to be blocked by the bay’s western boundary in the narrow-shelf region. The ensuing wave–coast interaction amplifies the wave amplitude and the cross-shelf transport. Because the interaction only occurs near the western boundary, the shelf water in the west of the bay is more readily carried offshore than that in the east and the mean shelf circulation is also intensified along the bay’s western boundary.
Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies
Authors: Uleberg Kai-Erik , Munk Ane Cecilie , Brede Cato , Gudlaugsson Einar , van Diermen Bianca , Skaland Ivar , Malpica Anais , Janssen Emiel AM , Hjelle Anne , Baak Jan PA 
Published: June 2011

Abstract

Background
Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as "high grade", in spite of their different risk to cancer progression and spontaneous regression rates. CIN2-3 is usually diagnosed in formaldehyde-fixed paraffin embedded (FFPE) punch biopsies. This procedure virtually eliminates the availability of water-soluble proteins which could have diagnostic and prognostic value.

Aim
To investigate whether a water-soluble protein-saving biopsy processing method followed by a proteomic analysis of supernatant samples using LC-MS/MS (LTQ Orbitrap) can be used to distinguish between CIN2 and CIN3.

Methods
Fresh cervical punch biopsies from 20 women were incubated in RPMI1640 medium for 24 hours at 4°C for protein extraction and subsequently subjected to standard FFPE processing. P16 and Ki67-supported histologic consensus review CIN grade (CIN2, n = 10, CIN3, n = 10) was assessed by independent gynecological pathologists. The biopsy supernatants were depleted of 7 high abundance proteins prior to uni-dimensional LC-MS/MS analysis for protein identifications.

Results
The age of the patients ranged from 25-40 years (median 29.7), and mean protein concentration was 0.81 mg/ml (range 0.55 - 1.14). After application of multistep identification criteria, 114 proteins were identified, including proteins like vimentin, actin, transthyretin, apolipoprotein A-1, Heat Shock protein beta 1, vitamin D binding protein and different cytokeratins. The identified proteins are annotated to metabolic processes (36%), signal transduction (27%), cell cycle processes (15%) and trafficking/transport (9%). Using binary logistic regression, Cytokeratin 2 was found to have the strongest independent discriminatory power resulting in 90% overall correct classification.

Conclusions
114 proteins were identified in supernatants from fresh cervical biopsies and many differed between CIN2 and 3. Cytokeratin 2 is the strongest discriminator with 90% overall correct classifications.