bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Programming Conditions on the Triple‐Shape Effect of Copolymer Networks with Poly(ω‐pentadecalactone) and Poly(ε‐caprolactone) as Switching Segments
Authors: Zotzmann Jörg , Behl Marc , Lendlein Andreas 
Published: December 2011

AbstractA versatile triple‐shape material based on the two crystallizable segments poly(ω–pentadecalactone) and poly(ε‐caprolactone) was synthesized showing triple‐shape capability after application of the typical two‐step triple‐shape creation procedure at elevated temperatures (TSCP) as well as a one‐step programming procedure at high temperature or at room temperature by cold drawing. By applying TSCP and varying the sequence of programming temperatures, the influence of the programming procedure on the triple‐shape capability was investigated. The application of such a modified TSCP enabled to a certain extent the control of triple‐shape capability by influencing the crystallization behavior of the two switching segments in these copolymer networks.
Comparative Study of Collagen and Gelatin Coatings on Titanium Surfaces
Authors: Vanderleyden Els , Van Hoorebeke Luc , Schacht Etienne , Dubruel Peter 
Published: December 2011

AbstractThe vast majority of studies in the bone tissue engineering field are focused on the surface modification of titanium scaffolds to obtain integration of the scaffold in the surrounding bone tissue. Our approach consisted in benefiting from the advantages of the cell‐interaction capabilities of collagen and gelatin. The biopolymers were immobilised onto the Ti surface through different methods and the stability of the obtained coatings was determined. The obtained results reveal that covalent immobilisation of collagen and gelatin is required to obtain stable surface coatings.
Fluorophore‐Labeled Siloxane‐Based Nanoparticles for Biomedical Applications
Authors: Koshkina Olga , Bantz Christoph , Würth Christian , Lang Thomas , Resch‐Genger Ute , Maskos Michael 
Published: December 2011

AbstractWe present the synthesis and characterization of multifunctional fluorophore‐labeled poly(organosiloxane) nanoparticles with core‐shell architecture, where the fluorescent dye is incorporated into the core. Grafting of heterobifunctional poly(ethylene oxide) (PEO) onto the particle surface leads to water‐soluble biocompatible nanoparticles. Two different strategies have been used for the synthesis: The encapsulation of dye‐labeled monomers during the polycondensation with additional PEO coating and subsequent dye labeling by covalent attachment of the fluorescent dye rhodamine B to the (chloromethylphenyl)siloxane groups in the core after polymerization and grafting of PEO onto the surface. Comparison of the fluorescence quantum yields of the nanoparticles before and after PEO coating show a decrease in quantum yield after PEO coating.
Degradation Behavior of Porous Copolyester Microparticles in the Light of Dynamic Changes in Their Morphology
Authors: Mathew Simi , Lendlein Andreas , Wischke Christian 
Published: December 2011

AbstractThe pore structures of microparticulate drug carriers are important diffusion pathways, which are not a static property but rather may be changing in the case of degradable matrix polymers such as poly[(rac‐lactide)‐co‐glycolide] (PLGA). In this study, the mutual impacts of dynamic changes in microparticle porosity and polymer degradation were analyzed for PLGA with different molecular weights and end groups as well as PLGA‐based triblock copolymers. In selected cases, particularly for PLGA with hydrophilic end groups and low initial number average molecular weight of 5 kDa, pore opening/pore closing phenomena were detected during incubation in phosphate buffer at 37 °C. Initially, pore closing was induced by water‐induced plasticization and the reduction of interfacial tension. The pattern of molecular weight decrease and mass loss suggested that pore closing did not result in undesired autocatalytic acceleration of degradation or delayed mass loss due to trapped acidic degradation products.
Shape Memory RGD‐Containing Networks: Synthesis, Characterization, and Application in Cell Culture
Authors: Xu Xiuling , Davis Kevin A. , Yang Pine , Gu Xinzhu , Henderson James H. , Mather Patrick T. 
Published: December 2011

AbstractHydrogels have found wide application in tissue engineering and cell mechanobiology research due to their tunable, and often biomimetic, biochemical and biomechanical properties. Although it has been known for more than a decade that hydrogels can be designed to exhibit shape memory functionality—the ability to change from one defined shape to another when triggered by a defined stimulus—shape memory hydrogels have not previously been exploited in tissue engineering or mechanobiology research. Here we report the development of a biodegradable and biocompatible hydrogel with tailored shape memory as well as desirable mechanical property for soft‐tissue applications. A shape memory hydrogel was synthesized by photopolymerization of PCL3k diacry‐lates together with acrylate‐PEG2k‐GRGDS in the presence of a crosslinker, tetrathiol, and photoinitiator, DMPA, through thiol‐ene chemistry. Differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) were carried out to examine the thermal, mechanical and shape memory properties of the hydrogel in dry and wet states. Cell culture studies were performed to characterize material cytocompatibility. We found that the PCL phase was crystalline in the hydrogel, providing an excellent, reproducible shape memory effect. The transition temperature (shape memory “trigger”) was tuned to fall between room and body temperature. Both cell attachment and proliferation studies revealed that the presentation of GRGDS molecules in the hydrogel facilitated fibroblasts adhesion and spreading on the hydrogel surface. This hydrogel, tailored to exhibit shape memory behavior in the cell culture compatible temperature range, should provide new opportunities for “smart” shape‐changing scaffolds and substrates for application in tissue engineering and investigation of cell mechanobiology.
Comparison of office‐based versus home web‐based clinical assessments for Parkinson's disease
Authors: Cubo Esther , Trejo Gabriel‐Galán José M. , Seco Martínez Joaquin , Rioja Alcubilla Carlos , Yang Chengwu , Fernández Arconada Olga , Mariscal Pérez Natividad 
Published: December 2011

AbstractBackground:The feasibility and validity of Web‐based assessments in Parkinson's disease is unknown. The objectives of this study were to develop and to compare home Web‐based assessments with office‐based assessments.Methods: We tested feasibility and validity using a longitudinal, randomized crossover design. Patients were assessed at baseline and after 6 and 12 weeks using both assessments including the Unified Parkinson's Disease Rating Scale, the Unified Dyskinesia Rating scale, timed tests, and quality‐of life and Non‐Motor Symptoms questionnaires.Results:Forty‐two patients were included (22 men, 20 women; mean age, 64.7 ± 9.0 years). Only 2 patients (5%) dropped out. The mean intraclass correlation coefficient between Web‐ and office‐based assessments ranged from 0.67 (first visit) to 0.75 (last visit) and 0.81 and 0.82 for doctor‐ and patient‐administered scales, respectively. No differences in responsiveness (P = 0.63), and data precision (P = 0.11) were found, but Web‐based assessments had fewer missing values (P = 0.01).Conclusions:Web‐based assessments offer a feasible format for assessing PD‐related impairment from home. © 2011 Movement Disorder Society
Glucocerebrosidase mutations confer a greater risk of dementia during Parkinson's disease course
Authors: Setó‐Salvia Núria , Pagonabarraga Javier , Houlden Henry , Pascual‐Sedano Berta , Dols‐Icardo Oriol , Tucci Arianna , Paisán‐Ruiz Coro , Campolongo Antonia , Antón‐Aguirre Sofía , Martín Inés , Muñoz Laia , Bufill Enric , Vilageliu Lluïsa , Grinberg Daniel , Cozar Mónica , Blesa Rafael , Lleó Alberto , Hardy John , Kulisevsky Jaime , Clarimón Jordi 
Published: December 2011

AbstractMutations in the glucocerebrosidase gene are associated with Parkinson's disease and Lewy body dementia. However, whether these alterations have any effect on the clinical course of Parkinson's disease is not clear. The glucocerebrosidase coding region was fully sequenced in 225 Parkinson's disease patients, 17 pathologically confirmed Lewy body dementia patients, and 186 controls from Spain. Twenty‐two Parkinson's disease patients (9.8%) and 2 Lewy body dementia patients (11.8%) carried mutations in the glucocerebrosidase gene, compared with only 1 control (0.5%); P = .016 and P = .021 for Parkinson's disease and Lewy body dementia, respectively. The N370S and the L444P mutations represented 50% of the alterations. Two novel variants, L144V and S488T, and 7 previously described alterations were also found. Alterations in glucocerebrosidase were associated with a significant risk of dementia during the clinical course of Parkinson's disease (age at onset, years of evolution, and sex‐adjusted odds ratio, 5.8; P = .001). Mutation carriers did not show worse motor symptoms, had good response to L‐dopa, and tended to present the intermediate parkinsonian phenotype. Our findings suggest that mutations in the glucocerebrosidase gene not only increase the risk of both Parkinson's disease and Lewy body dementia but also strongly influence the course of Parkinson's disease with respect to the appearance of dementia. © 2011 Movement Disorder Society
An efficient second‐order model reduction enhanced by H‐LU for the finite element method full‐wave electromagnetic simulations
Authors: Li Mengmeng , Chen Rushan , Wan Ting , Feng Kun 
Published: December 2011

AbstractA hierarchical LU(H‐LU) decomposition‐based direct method enhanced second‐order Krylov subspace projection‐based model order reduction (MOR) is presented. The construction of the projection matrix is the most important process in the Krylov subspace projection‐based MOR, where an inverse of the sparse matrix is involved in the construction of the projection matrix. It will be intractable for the computational capacity of a personal computer when the size of the problem is large. A H‐LU decomposition‐based direct method is used to the MOR with almost linear complexity. Numerical results demonstrate the validity of the proposed algorithm. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:292–296, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26526
Lithium niobate photonic sensor for measurement of pulsed electric field with nanosecond risetime
Authors: Chen Kaixin , Sun Bao , Chen Fushen , Hu Zhefeng , Cao Yongsheng 
Published: December 2011

AbstractLithium niobate‐based photonic sensor with Mach–Zehnder optical waveguide interferometer and tapered antenna array was designed and fabricated for measuring pulsed electric field with nanosecond risetime. The fabricated photonic sensor exhibits relatively flat frequency response with a variation not more than 4 dBm from 10 kHz to 5 GHz and minimum detectable electric field intensity of 0.4 V/m. A 103 V/m pulsed electric field with nanosecond risetime was also measured by this photonic sensor, the experimental results exhibit the information of electromagnetic pulse can be detected and extracted by this photonic sensor. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:421–423, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26531
Asymmetric‐arm printed dipole antenna for wlan applications
Authors: Wang Yang‐Jing , Lei Zhen‐Ya , Zhang Na , Cai De‐Shui , Wang Ya‐Fang 
Published: December 2011

AbstractA novel printed dipole antenna for wireless local area networks (WLAN) applications is presented in this article.The proposed antenna, characterized by dual‐band, low cross‐polarization, and small‐size, consists of two asymmetric tapered arms. A novel feed scheme is employed to realize a balanced feed. For validation, the antenna prototype is fabricated and measured. The performance of the antenna is verified and characterized in terms of return loss, radiation pattern, and gain. The simulated and measured results show good agreement. Details of the proposed antenna design and tested results are presented and discussed. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:354–358, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26534
Dual‐band bandpass filter using novel side‐stub‐loaded resonator
Authors: Wu Xiao‐Hu , Chu Qing‐Xin , Tian Xu‐Kun 
Published: December 2011

AbstractIn this letter, a microstrip dual‐band bandpass filter (BPF) using novel side‐stub‐loaded resonator has been presented.By loading two open stubs at the symmetrical sides of a uniform‐impedance resonator, the center frequency of the fundamental odd mode could be independently controlled while that of the fundamental even mode is fixed. A dual‐band filter using pseudo‐interdigital configuration is implemented with three transmission zeros. To validate the design and analysis, a dual‐band BPF has been designed and fabricated with its two bands located at 2.4/5.2 GHz. It is shown that the measured and simulated performances are in good agreement. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:362–364 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26537
Application of lensed fiber collimator to miniature CWDM filter device
Authors: Lin Yu‐Cheng 
Published: December 2011

AbstractBecause of the miniature trend in most fiber optic device, we propose and experimentally verify a coarse wavelength division multiplexing (CWDM) device with lensed fiber collimators. Our key idea is to use a tiny gradient index fiber lensed fiber less than the dimension of ø0.14 × L0.5 mm to replace the traditional gradient index lens collimator ø3.2 × L11 mm. The insertion loss of a pair of 0.27 pitch lensed fiber collimator is measured in both axial and lateral direction. Then, the thin film filter is sandwiched with the lensed fiber collimators to work as CWDM device. Our experimental result shows the center wavelength and bandwidth are 1549 and 17 nm, respectively. Furthermore, owing to the tiny size and low cost, the lensed fiber collimator will provide a wide utilization in the design of other passive devices and biosensors. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:319–322 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26539
A low power UWB low noise amplifier using current reused and feedback techniques
Authors: Galal A. I. A. , Pokharel R. , Kanaya H. , Yoshida K. 
Published: December 2011

AbstractThis letter presents a full band low power low noise amplifier design in 0.18‐μm complementary metal‐oxide‐semiconductor FET (CMOS) technology.The proposed circuit adopts current reused technique to achieve low power consumption, and shunt resistive feedback for wide‐band operation. An excellent wide and flat gain, low noise figure, are achieved by composes of these techniques. The implemented ultra‐wideband (UWB) low noise amplifier (LNA) exhibits a flat gain of 18 dB with total power consumption of 5.2 mA from 1.8 V power supply. The noise figure is 3.1 dB within the entire bandwidth. The input and output return loss is less than −10 dB in the specified bandwidth. The proposed technique exhibits 0.8 dBm of IIP3. The active die area of UWB LNA occupies 0.72 mm2. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:471–474, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26550
Design of a novel compact broadband patch antenna using binary PSO
Authors: Wang N. Z. , Wang X. B. , Xu J. D. 
Published: December 2011

AbstractIn this article, a C‐Band broadband patch antenna is designed. The binary particle swarm optimization (BPSO) combining with IE3D software is adopted to broaden the bandwidth of the patch antenna automatically. Characteristics of the antenna are calculated using the well‐known Zeland IE3D software package while the bandwidth characteristic of the antenna is optimized using BPSO technique. The comparison results show that the 3.2% impedance bandwidth (4.63–4.78 GHz) of the patch antenna is upgrade to 10.4% (4.47–4.96 GHz) through the BPSO‐IE3D method. The antenna gain is stable and the radiation patterns are similar in configuration over the whole operating frequencies to that of a conventional patch antenna. A prototype of the optimized antenna has been fabricated and important antenna parameters such as reflection coefficient (S11) parameter, gains and radiation patterns are measured using Network Analyzer and antenna test‐bench. The measured values of the antenna parameters are found to match well with that of the simulated results, all of which illustrate that the method is valid and the antenna can operate well. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:434–438, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26552
Investigations on an improved interstitial antenna used for microwave hyperthermia and the specific absorption rate distribution within biological tissues
Authors: Li Li , Che Wenquan , Chang Yumei 
Published: December 2011

AbstractHepatocellular carcinoma is one of the common tumors in the world, which leads to more than 600,000 deaths per year.Microwave hyperthermia has been widely used in hepatocellular carcinoma treatment, whereby the cancer cells are heated and killed by making use of the different thermal sensitivity of the cancer cells and normal cells. Monopole is used to be microwave radiator in recent years; however, the ablation region is elongated along the antenna insertion direction so that the skin and normal tissue around the tumor is also heated unexpectedly. It is desirable to generate a heating region in the vicinity of the antenna tip in a spherical manner. To solve the issue, a coaxial‐slot antenna with choke is proposed in the article, the specific absorption rate (SAR) distribution around antenna is computed by means of the finite difference time domain method. By comparison with the SAR distribution caused by monopole antenna, it is clear that no unnecessary heating region is generated near the surface of the body when the improved antenna is used. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 54:405–409, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26553
Printed dual dipole antenna with modified taper matching for wlan communication
Authors: Lee Hyeonjin , Jung Jinwoo , Lim Yeongseog 
Published: December 2011

AbstractIn this letter, a printed dipole antenna for wireless local area network (WLAN) communication is proposed.The proposed antenna consists of two dipole strips, which have modified dual monopoles and modified strip arms with tapered matching by the ground plane. The proposed antenna is increased radiation gain than the conventional dipole structure. The operating frequency band of the antenna is able to support WLAN of 5∼6.45 GHz. The measured peak gain is 4.8 dBi at 5.3 GHz. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:398–401, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26560
Design of a broadband reflectarray using meander‐shaped elements
Authors: Zhao J.‐J. , Gong S.‐X. , Xu Y.‐X. , Ren L.‐S. 
Published: December 2011

AbstractA novel cell element, the combination of meander‐shaped rectangle and ring, is presented for reflectarray. The feature of the cell element is investigated along with the design of the feed and array. A 52‐element array prototype based on the proposed element has been fabricated and measured showing good results over a 26% 1‐dB gain bandwidth. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:500–503, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26563
Generation of a narrow microwave carrier from a bimodal fiber laser
Authors: Ferreira da Silva T. , Thomas D.H. , von der Weid J. P. 
Published: December 2011

AbstractWe report the heterodyne generation of a narrow radiofrequency carrier by the beat of the signal of a bimodal fiber laser. The bimodal operation of the designed multiple‐cavities‐filter‐based laser is presented, as well as the measured narrow microwave tone, suitable for modern microwave photonics links. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:416–421, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26566
Zero phase velocity error finite‐difference time‐domain method for small space step and large time step sizes
Authors: Kusaf Mehmet , Oztoprak Abdullah Y. 
Published: December 2011

AbstractUnconditionally stable multi (4, 6, and 8) split‐step finite‐difference time‐domain methods are isotropic for a certain space step size and a stability factor.It is shown in this letter that for small step sizes the phase velocity errors can be corrected by using a factor which is a function of the product of the space step size and the stability factor. This way, it is not necessary to obtain the multiplication factor each time when a different space step size is used. Also, by using this multiplication factor zero phase velocity error can be obtained in all directions at a chosen frequency. Performance analyses have shown that the method is also wideband. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:423–426, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26567
A single‐FED slot‐aperture hybrid antenna for broadband circular polarization operations
Authors: Lu Yu‐Chun , Yu Ming‐Je , Lin Yi‐Cheng 
Published: December 2011

AbstractThis article presents a microstrip‐fed slot‐aperture hybrid antenna for wideband circularly polarized (CP) operations. The antenna consists of a U‐shaped slot, a rectangular aperture, and a probing strip fed by a microstrip line. In general, the U‐shaped slot and the rectangular aperture resonate at two separate frequencies. When properly arranged, the proposed antenna may resonate over a single wideband of CP radiation. The 3‐dB axial ratio (AR) bandwidth of the presented antenna in free space is about 27% with the gain level about 34 dBic. When a planar reflector is incorporated for the desirable unidirectional pattern, the presented antenna has an enhanced gain about 7 dBic with a 3‐dB AR bandwidth of 25% and a front‐to‐back ratio of about 14 dB. Good agreement between measured and simulated results was achieved. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:412–415, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26569
Tunable fourth LO‐harmonic mixer using CRLH‐TL and varactor diode
Authors: Zhao Shiwei , Tang Zongxi , Guo Fanyu , Su Ping 
Published: December 2011

AbstractA novel fourth order harmonic mixer using composite right/left handed transmission lines and varactor diode is presented.The structure provides more flexible phase for suppressing spurious signals and improving conversion loss. Compared with conventional harmonic mixer, the measured results show that 10.4 dB conversion loss and 80 dB suppression of unwanted harmonics are achieved when local oscillator signal power is 7 dBm at 5 GHz. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:543–545, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26575