bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taphonomy and contextual Zooarcheology of the first Mesolithic hunting station in Thuringia, central Germany, (central Europe)
Authors: Karl Hans-Volker , Paust Enrico , Safi Amtyaz 
Published: February 2025

Taphonomy and contextual zooarcheology of the first Mesolithic hunting station in Thuringia, Central-Germany (Central Europe) was the study area of this paper. The new site at GÃ¶ttern is of special importance as it is the first excavated hunting station in Thuringia. Until now, we have depended upon numerous discoveries of surface finds, special single finds and a few burials, for the exploration of the Mesolithic Era. Bone remains of wild boar/pig, red deer, moose, roe deer, aurochscattle, wild horse, brown bear, wolf/ dog, mouse and birds have been discovered.Â Â
Determinants of voter turnout in 2015 Tanzania general election: a case of morogoro municipality, Tanzania
Authors: Muhanga Mikidadi 
Published: February 2025

Worldwide votersâ€™ turnout shows a notable decline since the mid 1980s, this is a challenge to democratization process. A number of efforts have been in place to address this, still a great proportion of registered voters do not vote in the elections as revealed in 1995, 2000, 2005 and 2010 General elections in Tanzania. This study was designed to assess the context specific determinants of votersâ€™ turnouts in Tanzania general election in Morogoro municipality after all the efforts by various stakeholders to address low turn outs experienced in earlier elections. Specifically the study determined votersâ€™ turnouts and analyzed motives for voting. A cross- sectional study design was employed. Questionnaire was used as a tool for data collection to gather both qualitative and quantitative information. Multistage sampling was employed. Data were collected from four randomly selected wards from Morogoro urban (purposively selected) in Morogoro region namely Kichangani, Tungi, Mazimbu and Mji Mpya where in each ward 60 individuals were drawn randomly. Data processing and analysis was done using Statistical Package for Social Sciences (SPSS) computer software. Chi-square test indicates significant associations between marital status and voting (p = 0 .000), voters education and the likelihood of voting (p = 0.000) and access to information and the likelihood of voting (p = 0 .001). The motives for turning to vote in general election in the study area were leadership role towards development (22.5%), exercising democracy (17.5%), good policies of political parties and manifestos (20.0%) and achievement done by former leaders (15.0%), good promises made by candidates during campaigns (10.0%) and voted to avoid corrupt leaders (15.0%). The study recommends for provision of civic education programme to citizens through various means and rigorous campaigns to disclose candidatesâ€™ potentialities.Â Â
In situ supported rhodium catalyst on mesoporous silica for chemoselective hydrogenation of nitriles to primary amines
Authors: Ajjou Abdelaziz Nait , Robichaud André , Rahman Ateeq 
Published: February 2025

Abstract
Heterogeneous rhodium supported on mesoporous silica (Rhinsitu/mesSiO2) was easily prepared, in one step, by incorporating rhodium units onto the silica framework during the sol–gel process. Rhinsitu/mesSiO2 was revealed to be an excellent active and selective catalyst for the hydrogenation of aromatic, heteroaromatic, aliphatic nitriles, and aliphatic nitriles bearing aromatic or heteroaromatic rings to primary amines, regardless of their steric hindrance. The catalytic system that is efficiently recyclable operates under mild conditions in the presence of ammonia.
Effect of polyvinyl acetate on the properties of biodegradable thermoplastic starch/polyethylene glycol blends
Authors: Cheng Wenxi , Miao Wei , Li Wentao , Jiang Zhiwei , Song Weiqiang , Lin Haowei , Shang Mengya , Zhang Yike , Cheng Bo 
Published: February 2025

Abstract
Thermoplastic starch (TPS)/polyethylene glycol (PEG)/polyvinyl acetate (PVAc) blends were prepared through melt blending, in which PEG content was fixed at 5 wt% and PVAc content ranged from 10 wt% to 20 wt%, with increments of 5 wt%. For comparison, a TPS/PEG blend was also prepared. All the blends were subsequently characterized using various techniques. Differential scanning calorimetry (DSC) results showed that the melt temperatures (T
m) of TPS and PEG in all blends remained independent, indicating immiscibility of TPS and PEG. Notably, T
m of TPS weakened upon the addition of PVAc, and the effect was particularly pronounced in the blend containing 15 wt% PVAc, whose T
m disappeared and a cold crystallization temperature (T
cc) emerged, suggesting a crystal hindering effect exerted by PVAc on TPS. X-ray diffraction (XRD) results further supported this finding, showing that PVAc primarily inhibited the formation of VA-type crystals in TPS and slightly increased starch retrogradation. Scanning electron microscopy (SEM) images revealed that starch plasticization increased with higher PVAc content, and TPS particles agglomerated into larger nodules. Tensile testing demonstrated that the ternary blends exhibited enhanced strength, while PEG did not contribute to the toughness of the system. Additionally, the thermal resistance, equilibrium moisture adsorption, and biodegradation stability of the ternary blends improved with the incorporation of PVAc. It is evident that in TPS/PEG/PVAc ternary blends, PVAc retained its reinforcing and crystallinity-reducing effect, whereas the toughening effect of PEG was absent.
Efficient non-Hermitian wave-modulation protocol with a rapid parametric jump
Authors: Shin Seung Han , Choi Yu Sung , Kim Yae Jun , Yoon Jae Woong 
Published: February 2025

Abstract
Non-Hermitian photonic wave modulators utilizing exceptional points (EPs) was previously proposed as a potential approach to realize high-performance and compact optical modulators. However, their practical implementation has been restricted by their substantial footprint size limit due to stringent adiabatic conditions near EPs. Here, we demonstrate a principle for efficient wave modulation through optimized parametric trajectories around an EP. By employing rapid encirclement or parametric jump over the EP, we achieve an extinction ratio of 43 dB within a total device length of 15 coupling-length unit. Importantly, we show that adiabatic processes around the EP in the initial stage of the entire evolution can be replaced by an instantaneous parametric jump without compromising the switching performance in stark contrast to the conventional wisdom from the standard adiabaticity.
Efficiency optimization of quantum dot photovoltaic cell by solar thermophotovoltaic system
Authors: Talha Hafiz Muhammad , Rana Ahsan Sarwar , Shahid Saleem , Khan Waseem , Naeem Taimoor , Aslam Muhammad , Bahajjaj Aboud Ahmed Awadh , Asghar Aamer Bilal , Conka Zsolt , Stefko Robert 
Published: February 2025

Abstract
Obtaining electrical power from solar energy through photovoltaic (PV) cell is an excellent alternative to harvesting energy from fossil fuels. However, efficiency is one of the main concerns as the Shockley–Queisser limit puts an upper bound to the efficiency of PV cell. Solar Thermophotovoltaic (STPV) systems are a viable solution to overcome this limit, but they require efficient and meticulous designs of broadband solar absorber and spectrally selective emitter. These designs require high-temperature tolerance, polarization angle and incidence angle insensitivity, and oxidation resistance to endure high-temperature and harsh environmental conditions. This work presents a Titanium carbide-based ultra-broadband absorber and Platinum-based thermal emitter, both of which are reasonable candidates for STPV applications owing to their high melting points. The proposed absorber has a pyramid design as a top nanostructure layer, while the emitter has gratings on its top. The emitter is optimized for lead sulfide (PbS)-based colloidal quantum dot (CQD) PV cell, having a bandgap energy of 0.41 eV, which is an emerging PV cell technology. The proposed absorber exhibits high efficiency of 96%, while the selective emitter achieves PV cell efficiency of 35.2% for PbS based CQD PV cell at the temperature of 1,350 K.
КРИТЕРИИ ОБЪЕКТНОСТИ: ВНУТРЕННИЕ СВОЙСТВА
Authors: СУХАРЕВА В.А. 
Published: February 2025

В статье рассматривается тезис о неполноте математических объектов, из которого эксплицируется критерий внутренних свойств. Реконструируются два обоснования критерия внутренних свойств, анализируются необходимость и достаточность данного критерия в качестве самостоятельного метафизического критерия объектности. Показано, что оба обоснования критерия внутренних свойств уязвимы к критике. Приведены следующие возражения: во-первых, объекты могут иметь критерии тождества, не имея внутренних свойств; во-вторых, не все математические объекты лишены внутренней определенности; в-третьих, независимость существования объекта не имеет необходимой связи с наличием у него внутренних свойств. Сделан вывод о том, что критерий внутренних свойств сам по себе не может считаться ни необходимым, ни достаточным критерием объектности.
The article considers the thesis of incompleteness of mathematical objects, from which the criterion of intrinsic properties is explicated. Two justifications of the criterion of intrinsic properties are reconstructed; the necessity and sufficiency of this criterion as an independent metaphysical criterion of objecthood are analyzed. It is shown that both justifications are vulnerable to criticism. The following objections are raised: firstly, objects can have criteria of identity without having intrinsic properties; secondly, not all mathematical objects lack intrinsic determinacy; thirdly, an independent existence and intrinsic properties do not necessarily imply each other. The conclusion is made that the criterion of intrinsic properties in itself can be considered neither a necessary nor a sufficient criterion of objecthood.
Mitral Valve Aneurysms Complicating Aortic Valve Endocarditis: A Case Series.
Authors: AGRAWAL DR SHRIRAM , KUMAR DR M VIJAY , C DR RAJIV , VERMA DR PRAVIN 
Published: February 2025

Background: Mitral valve aneurysms (MVAs) are uncommon conditions frequently associated with aortic valve endocarditis. They may be complicated by perforation and severe mitral regurgitation (MR). Optimal treatment of MVA, and in particular the best timing for surgery, are uncertain.
Case Presentation: We report three cases of MVAs complicating aortic valve endocarditis:
Case 1: A 56-year-old male with acute pulmonary edema secondary to severe aortic and mitral regurgitation underwent emergency double valve replacement. Despite initial postoperative stability, he later succumbed to complications.
Case 2: A 33-year-old female developed severe regurgitation of both valves and multiple cerebral infarctions post-febrile illness. Due to the COVID-19 pandemic, her double valve replacement was delayed, but she recovered well after surgery.
Case 3: A 41-year-old male, initially evaluated for renal transplant, was incidentally found to have severe aortic regurgitation and MVA. He successfully underwent elective aortic valve replacement and mitral valve repair.
Details: The first patient had Severe AR and MR, presented with pulmonary edema, and underwent double valve replacement. The second patient had a prolonged course of relapsing and remitting fever for one and half years which was initially treated by broad-spectrum antibiotics, complicated by CVA, had severe MR and AR, and underwent double valve replacement. The third patient had unexplained pulmonary edema even after regular dialysis and as a pre-operative check-up had AV endocarditis with MVA causing severe AR and MR and underwent AVR with MV repair. All patients had mechanical valves for replacement and MV repair by pericardial patch.
Conclusions: MVAs are infrequent but potentially severe complications of AV endocarditis. In the absence of definite treatment indications, the correct time for surgery should depend on concomitant clinical and infective features.
« Résoudre le syndrome de la page blanche de Laurine ». Quand le dispositif échoue ou qu’il réussit trop bien
Authors: Lebrun Léo 
Published: February 2025

Cet article est une « monographie », au sens où la définit la Pédagogie Institutionnelle. Écrite par quatre formateurs en travail social, elle donne à voir une situation de blocage face à l’écriture, blocage nommé par l’étudiante concernée comme le résultat du « syndrome de la page blanche ». Le formateur engagé dans cette situation partage avec trois de ses collègues formateurs des réflexions et des hypothèses d’analyse autour de ce que cet empêchement et sa propre volonté de résoudre « à tout prix » ce problème peuvent signifier. L’introduction et la première partie du texte donnent des éléments permettant de comprendre ce qu’est une monographie, à la fois en tant que processus d’élaboration sur la pratique et en tant que production d’un type particulier d’écrit professionnel. La seconde partie de l’article est la monographie proprement dite.
Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors
Authors: von Delft Frank , Ni Xiaomin , Richardson R. , Godoy Andre , Ferla Matteo , Kikawa Caroline , Scheen Jenke , Hannon William , Capkin Eda , Lahav Noa , Balcomb Blake , Marples Peter , Fairhead Michael , Wang SiYi , Williams Eleanor , Tomlinson Charles , Aschenbrenner Jasmin , Lithgo Ryan , Winokan Max , Giroud Charline , Chandran Anu , Walsh Martin , Thompson Warren , Bloom Jesse , Barr Haim , Kirkegaard Karla , Koekemoer Lizbé , Fearon Daren , Evans Matthew 
Published: February 2025

Abstract

The Zika viral protease NS2B-NS3 is essential for the cleavage of viral polyprotein precursor into individual structural and non-structural (NS) proteins and is therefore an attractive drug target. Generation of a robust crystal system of co-expressed NS2B-NS3 protease has enabled us to perform a crystallographic fragment screening campaign with 1076 fragments. 47 fragments with diverse scaffolds were identified to bind in the active site of the protease, with another 6 fragments observed in a potential allosteric site. To identify binding sites that are intolerant to mutation and thus suppress the outgrowth of viruses resistant to inhibitors developed from bound fragments, we performed deep mutational scanning of NS2B-NS3 protease. Merging fragment hits yields an extensive set of ‘mergers’, defined as synthetically accessible compounds that recapitulate constellations of observed fragment-protein interactions. In addition, the highly sociable fragment hits enable rapid exploration of chemical space via algorithmic calculation and thus yield diverse possible starting points that maximally explore the binding opportunities to NS2B-NS3 protease, facilitating its resistance-resilient antiviral development.
Handling electric connections in 3D-printed electrodes and sensors. Part II. Instrumentation
Authors: de Oliveira Thawan Gomes , Verlangieri Ivan , Lopes Fernando Silva , Gutz Ivano Gebhardt Rolf , Angnes Lúcio , Lago Claudimir Lucio do 
Published: February 2025

Abstract

This study explores the integration of 3D-printed electrodes made from carbon black-poly(lactic acid) (CB-PLA) into electrochemical sensors, focusing on the challenges posed by the polymer/metal electrical contact resistance (ECR) and Ohmic drop. We demonstrate that while CB-PLA electrodes offer promising potential for sensor applications, the ECR and intrinsic resistance of printed tracks can significantly affect the performance. We propose the use of a four-electrode potentiostat, which allows for dynamic compensation of Ohmic drop, thereby enhancing the reliability of measurements. We conducted cyclic voltammetry experiments using a custom-built 3D-printed electrode with dual conducting tracks to independently monitor potential and current. The results obtained with a commercial four-electrode potentiostat were compared to those from a conventional three-electrode potentiostat. To enable users without a four-electrode potentiostat to use the described electrode, a four-electrode potentiostatic module (FEPM) was developed. The results from combining a three-electrode instrument with the FEPM are comparable to those from a commercial four-electrode instrument. Quantitative analysis revealed that the peak current varied linearly with analyte concentration (R² = 0.992) and with the square root of the scan rate, showing high correlation coefficients for both cathodic (R² = 0.993) and anodic (R² = 0.999) peak currents. Differential pulse voltammetry experiments further confirmed the improved performance of the four-electrode setup, with comparable results obtained using the three-electrode potentiostat and FEPM combination. These findings underscore the importance of careful instrumentation design when integrating 3D-printed components into electrochemical systems, and suggest practical approaches for mitigating ECR and Ohmic drop in such applications.
Research on the Impact of Excessive Environmental Information Disclosure by Enterprises on Stock Price Crash
Authors: Dong Guoping , Ma Guifen 
Published: February 2025

Abstract

This paper investigates the phenomenon of excessive environmental information disclosure by A-share listed companies in China. Using a sample of A-share listed companies that published corporate social responsibility (CSR) reports between 2015 and 2023, the study first applies the threshold effect and quantile regression models to identify embellishments in the environmental textual information disclosed by these firms. Subsequently, a panel fixed effects model is employed to examine the potential impact of excessive environmental information disclosure on stock price crashes. The results reveal that the environmental textual information disclosed by companies contains embellishments beyond substantive environmental content, indicating the presence of greenwashing. This behavior amplifies the risk of stock price crashes, with a more pronounced effect in the manufacturing sector. The underlying mechanism is that excessive textual information disclosure diminishes the quality and transparency of the disclosed information, thus fostering irrational investment behaviors among investors. Additionally, the study finds that effective environmental textual information disclosure can attenuate the likelihood of stock price crashes. Further analysis suggests that reducing ownership concentration, increasing managerial equity ownership, and enhancing the role of independent directors in corporate governance can significantly improve the quality of environmental information disclosure and curb excessive environmental information embellishment. This paper provides new insights into the analysis of environmental textual information disclosure and offers practical implications for guiding investors toward more rational investment decisions.
CircRNA signatures define ATLL subtypes and uncover the HBZ-DHX9 axis in tumor survival
Authors: Ladet Julien , Bazire Mateo , Fontrodona Nicolas , Broeke Anne Van den , Marçais Ambroise , Shallak Mariam , Forlani Greta , Accolla Roberto S. , Bourgeois Cyril F. , Mortreux Franck 
Published: February 2025

Abstract

Circular RNAs (CircRNAs) are emerging as critical regulators in leukemia biology; however, their role in Adult T-cell Leukemia/Lymphoma (ATLL) remains unexplored. In this study, we provide the first comprehensive profiling of circRNAs in ATLL subtypes, uncovering distinct circRNA signatures in acute, chronic, and lymphoma forms of the disease. Notably, circAFF2(3) was markedly upregulated in aggressive ATLL subtypes, suggesting its involvement in disease progression. Functional assays revealed that circAFF2(3) promotes cell viability in HTLV-1-transformed T cells, highlighting its potential as a tumor-promoting factor. Mechanistically, we demonstrate that the HTLV-1 viral protein HBZ interacts with the RNA helicase DHX9, a key regulator of circRNA biogenesis, and inhibits its unwinding activity at intronic regions flanking circularized exons, including those responsible for circAFF2(3) production. These findings establish the HBZ-DHX9 axis as a critical mechanism driving circRNA dysregulation and tumor survival in ATLL, offering new opportunities for biomarker discovery and therapeutic intervention.
Novel Small Molecule DZ-865B Effectively Degrades BCL6, Promotes Apoptosis and Reduces Proliferation of Diffuse Large B-Cell Lymphoma Cells
Authors: Wang Yanfeng , Jiang Beier , Yin Yichen , Li Tao , Chen Jing 
Published: February 2025

Abstract

B-cell lymphoma 6 (BCL6) is a transcriptional repressor essential for B lymphocyte differentiation and germinal center formation through its BTB structural domain. Overexpression of BCL6 is strongly implicated in the progression of diffuse large B-cell lymphoma (DLBCL), making it a promising therapeutic target. This study aims to identify a novel small molecule, synthesized via proteolysis-targeting chimeras (PROTACs), capable of degrading BCL6, thereby inhibiting DLBCL growth and providing a foundation for future preclinical studies. The expression of BCL6 in DLBCL was analyzed using The Cancer Genome Atlas (TCGA) database and the Human Protein Atlas. Western blotting assays confirmed BCL6 expression in tumor cell lines, leading to the identification of the small molecule compound DZ-865B. To evaluate DZ-865B’s in vitro efficacy, multiple assays were performed, including protein immunoblotting, immunofluorescence, quantitative PCR, EDU proliferation, and soft agar cloning assays. TCGA analysis revealed significant overexpression of BCL6 in DLBCL (P < 0.05), corroborated by immunohistological staining and western blotting. DZ-865B induced BCL6 degradation in DLBCL cell lines (OCI-LY-1 and SU-DHL-4) in a concentration- and time-dependent manner, reducing nuclear BCL6 levels. Notably, DZ-865B did not alter BCL6 mRNA levels but modulated downstream gene expression, leading to the activation of apoptosis pathway proteins and inhibition of DNA synthesis, effectively suppressing DLBCL cell growth. This study demonstrates that the small molecule DZ-865B targets and degrades BCL6 in DLBCL cells, promoting apoptosis and inhibiting cellular proliferation. These findings highlight DZ-865B as a potential therapeutic agent for diffuse large B-cell lymphoma.
Parental Involvement in Language Development: A Comparative Synthesis of Bilingual and Monolingual Children
Authors: GAY ERWIN 
Published: February 2025

Abstract

Background
Parental involvement is recognized as essential for the educational success of young children, facilitating academic achievement and socio-emotional and cognitive development. This paper integrates current research on parental involvement in bilingual and monolingual children aged 3 to 8, emphasizing the impact of these practices on language, literacy, and cognitive development. This study employs an inductive synthesis approach to highlight the similarities and differences in parental strategies, particularly in managing linguistic complexities in bilingual versus monolingual households. It examines the distinct challenges bilingual families face, such as balancing two languages and preserving cultural identity, compared to the more straightforward approaches of monolingual families, which typically emphasize one language.
Results
The findings indicate that bilingual children benefit from metalinguistic awareness and cognitive flexibility due to their exposure to two languages, while monolingual children often experience accelerated proficiency in their primary language. The study also underscores the importance of targeted interventions for both groups, suggesting that bilingual families require support in managing language exposure, while monolingual families may need assistance in overcoming socioeconomic barriers to literacy.
Conclusion
The paper provides practical insights for educators, policymakers, and families to create targeted interventions that foster children’s equitable developmental opportunities in varied linguistic contexts.