bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complex Hydride Reductions of 12‐Oxosteroids. Influence of Remote Substituents
Authors: Biesemans M. , Van Woude G. De , van Hove L. 
Published: September 2010

AbstractA number of 12‐oxosteroids with both 5α‐ and 5β‐configuration and with variable side chain are reduced with LiAlH4, NaAlH4 and Li[Al(Ot‐Bu)3H] in THF and diethylether. The ratio of the epimeric 12‐alcohols obtained, exhibits a remarkable dependence on the type of A/B ring fusion and on the C‐17 substitution. An evaluation of these effects is made in the light of generally accepted rationalizations on the mechanism of ketone reductions by hydride reagents.
Potentiometric Measurements in Water/Ethanol Medium
Authors: Abdel‐Rahman L. H. , Herman G. G. , Goeminne A. M. , Mahmoud M. R. 
Published: September 2010

AbstractA glass electrode calibration method is described for potentiometric pH‐measurements in a water‐ethanol solvent mixture. The method is checked by determining the protonation constants of glycine, β‐alanine, L‐tryptophane, L‐methionine and DL‐ethionine in water/ethanol (43% weight ethanol) (I=0.1 M KNO3) at 25°C. The binary complex formation of these amino acids with Co(II), Ni(II), Cu(II) and Zn(II) has also been investigated, together with the ternary complex formation with 2,2′‐bipyridyl as second ligand. The solvent effect is discussed.
New Polymers by Olefin Polymerization with Aluminoxane Containing Catalysts
Authors: Kaminsky Walter , Möller‐Lindenhof Nico 
Published: September 2010

AbstractHighly active catalysts for the polymerization of olefins are formed by combination of metallocenes and methylaluminoxane. Both components are soluble in hydrocarbons. An unusually wide field of syntheses of different polyolefins is opened up by the mere variation of the ligands coordinated to the transition metal.
2,2,4‐Trichlorobutanal: An Invitation to the Synthesis of Heterocyclic Compounds
Authors: De Buyck L. , Menke N. , Schamp N. 
Published: September 2010

AbstractThe title aldehyde (1) was obtained in 69% isolated yield by chlorination of 4‐chlorobutanol in the presence of dimethylformamide. 3,3‐Dichloro‐2‐hydroxytetrahydrofuran (3a) or the 2‐alkoxyderivatives 3b and 3c were produced by treating the hydrate 2a or the hemiacetals 2b and 2c resp. with base. With aqueous ammonia 1 rapidly formed the hemiaminal which then slowly afforded 3,3‐dichloro‐σ1‐pyrroline (4). In a rapid reaction with primary alkylamines 1 was converted to N‐alkyl‐3,3‐dichloro‐2‐hydroxypyrrolidines (5). The 2‐hydroxyl group in 5 was reversibly exchanged in the presence of alcohols or amines. 5 Were converted to N‐alkyl‐3,3‐dichloro‐σ1‐pyrrolinium salts by an excess of trifluoroacetic acid.
1,3‐Dipolar Cycloadditions of some Azomethine Ylides to Thioketones
Authors: Mloston Grzegorz , Skrzypek Zuzanna 
Published: September 2010

AbstractReactions of the azomethine ylides generated from cis‐1‐substituted‐2,3‐diphenylaziridines 1a‐b or from 1,2,3‐triazoline 5 with thiobenzophenone, adamantanethione and 2,2,4,4‐tetramethyl‐3‐thioxocyclobutanone are described.
The Dependence of Endopeptolysis on the Sequential Chirality Exemplified by a Simplified Preparation of the |D‐MePhe−4| ‐Epimer of Virginiamycin s.
Authors: Anteunis M. J. O. , Van Auwera C. Der , Sharma N. K. 
Published: September 2010

AbstractThe 4‐epimer of Virginiamycin S (VS‐epi4) containing the heterochiral triad L‐Pro−3‐D‐MePhe−4‐L‐(γOxo) Pec−5 is found to be resistant against acidic hydrolysis in contrast to the native VS possessing the L−3, L−4, L−5‐sequence. This allows a simplified protocol for its isolation, and exemplifies previous findings (ref. 1) about the easy endopeptolysis of homochiral triads.
Preparation and Properties of Zirconocene Complexes with Ferrocenylcarboxylate Ligand
Authors: Yong‐Xiang Ma , Zheng‐Zhi Zeng , Guo‐Sheng Huang , Chun‐Lin Ma 
Published: September 2010

AbstractSome zirconocene complexes containing ferrocenylcarboxylate ligands, [(RC5H4)2ZrCl]nY, R = H or CH3; n = 1, Y = ferrocenylcarbonyloxy, 2‐ferrocenylacetoxy, 4‐ferrocenylbutanoyloxy, 4‐ferrocenyl‐4‐oxobutanoyloxy, and 3‐(ferrocenylcarbony)lbicyclo[2,2,1]hept‐5‐ene‐2‐carbonyloxy; n = 2, y = bis[(3‐carboxypropionyl)cyclopentadienyl]iron, have been prepared. Their IR, −1H NMR, UV, and other determinations show that the carboxyl groups are bidentate ligands in these complexes.
Copper(II) Ion Transport Through Mono and Binary Liquid Membranes
Authors: Szpakowska Mariola , Fizycznej Zaklad Chemii , Nagy Ottó B. 
Published: September 2010

AbstractThe influence of membrane material and water phases acidity on coupled active copper transport by Acorga 5100 used as carrier has been examined. It was found that the efficiency of copper ion flux depends not only on proton concentration gradient across the membrane but also on the viscosity of the membrane solvent. However, both dependencies show saturation effects. Diffusion through the membrane phase turns out to be the rate determining step as shown by the accumulation of copper ions in the membrane and confirmed by partitioning measurements. Facilitated passive transport experiments showed that both the nature of the carrier and the composition of binary membranes influence strongly the transport rate. Varying membrane composition may even increase transport efficiency more than the use of better carrier. It was also found that the presence of surfactants have a favourable effect on the transport rate.
New Vertex Indices and their Applications in Evaluating Antileukemic Activity of 9‐Anilinoacridines and the Activity of 2′,3′‐Dideoxy‐Nuclosides Against HIV
Authors: Raychaudhury C. , Klopman G. 
Published: September 2010

AbstractA newly developed graph‐theoretical artificial intelligence program has been used to evaluate qualitatively the antileukemic activity of 9‐anilino‐acridines and the activity of 2′,3′‐dideoxy‐nucleosides against HIV. The idea behind the approach is to predict the biological activity of any chemical compound on the basis of already identified pharmacologically/toxicologically relevant components of the molecules exhibiting the same kind of activity. A family of new graph‐theoretical (topological) vertex indices called distance exponent indices (Dx) of molecular graph have been proposed and used in the present study. Two previously used information‐theoretical topological indices viz., vertex distance complexity (Vd) and normalized vertex distance complexity (Vdn) have also been used. However, some distance exponent indices have produced the most significant results. These indices appear to identify biologically relevant molecular components (vertices in our case) quite effectively. Subsequently, an experiment of cross‐validation has been carried out to analyze the predictive power of the present approach. The possible application of the vertex indices, considered here, in different databases has also been discussed.
Vibrational Analysis of New Macrocyclic Imine‐Carbinolamine Complexes of Nickel(II)
Authors: Amer S. A. , El‐Hefnawy G. B. , Saleim G. W. , Desseyn H. O. 
Published: September 2010

AbstractThe new macrocyclic imine‐carbinolamine complexes of nickel(II) have been prepared by reaction of 2,3‐diformylfurane and aliphatic diamines in ethanol in the presence of nickel(II) acetate or by simple addition reaction of the tetraaza‐macrocyclic ligand and NiX2 (X = chloride or acetate) in ethanol. The mode of coordination of these complexes has been studied through the vibrational analysis (i.r. and Raman) using the −58Ni/−62Ni isotopes technique.
Spectrophotometric Determination of CD(II) and Zn(II) with 1,2,3‐Cyclohexanetrione‐1,3‐Dioxime‐2‐Thiosemicarbazone. Simultaneous Determination by first and Second Derivative
Authors: Murillo José A. , Lemus José M. 
Published: September 2010

Abstract1,2,3‐Cyclohexanetrione‐1,2‐dioxime‐3‐thiosemicarbazone (CTDT), produces coloured complexes with zinc and cadmium ions in basic medium. The yellow colour obtained has been used to develop spectrophotometric methods for zinc and cadmium in the concentration range 1.30‐8.50 μg ml−1 of zinc and 1.20‐6.50 μg ml−1 of cadmium.A new method for the determination of zinc and cadmium in mixtures is proposed for concentrations between 0.5‐6.0 μg ml−1 and 0.8‐5.5 μg ml−1 by first derivative spectrophotometry and between 0.5‐6.0 μg ml−1 and 0.8‐5.5 μg ml−1 by second derivative spectrophotometry.
Selective Cleavage of the Ether and Amide Bonds in N‐(2,4‐Difluorophenyl)‐2‐[3‐(Trifluoromethyl)‐Phenoxy]‐3‐Pyridinecarboxamide (Diflufenican)
Authors: Rouchaud Jean , Gustin Fabrice , Moulart Claude , Herin Marc 
Published: September 2010

AbstractHeated to reflux in water containing 8 g% KOH, the herbicide diflufenican [N‐(2,4‐difluorophenyl)‐2‐[3‐(tri‐fluoromethyl)‐phenoxy]‐3‐pyridinecarboxamide, 1] was selectively transformed into 2‐[3‐(trifluoromethyl)‐phenoxy]‐3‐pyridinecarboxylic acid (2) plus 2, 4‐difluoroaniline (5); after 60 hr of heating, 27% of the initial diflufenican was transformed, yielding 21% (mole% relative to initial diflufenican) of compound 2. Heated to reflux in a mixture of acetic acid + concentrate hydrochloric acid, diflufenican was transformed into a mixture of N‐(2,4‐difluorophenyl)‐2‐hydroxy‐3‐pyridinecarboxamide (3) and 2‐hydroxy‐3‐carboxypyridine (4) plus 2,4‐difluoroaniline (5) and 3‐trifluoromethylphenol (6); after 48 hr of heating, diflufenican was completely transformed, yielding 28% (mole% relative to initial diflufenican) of compound 3, and 57% of compound 4. The base catalyzed hydrolysis thus selectively yielded compound 2; the acid catalyzed one yielded compounds 3+4: diflufenican first was transformed into compound 3, which thereafter was transformed into compound 4.
Characterisation by 2D Proton Nuclear Magnetic Resonance Methods of Z/E Isomeric States of the Linear Pentapeptide Pic(3′‐Oh)‐THR‐D‐Abu‐PRO‐Mephe‐Oh Derived From Virginiamycin S1
Authors: Jacob Elly M. F. , Anteunis Marc J. O. , Borremans Frans A. M. 
Published: September 2010

AbstractThe four Z/E isomeric states of the linear pentapeptide Pic(3′‐OH)‐Thr‐D‐Abu‐Pro‐MePhe‐OH are characterized by two‐dimensional proton NMR methods and some of their conformational features are discussed.The title compound as obtained from Virginiamycin S1 contains less than 5% of its epimer Pic(3′‐OH)‐Thr‐D‐Abu‐Pro‐D‐MePhe‐OH.
Synthesis of Rare Carbohydrates and Biomolecules from Furan
Authors: Vogel Pierre 
Published: September 2010

AbstractZinc iodide‐catalyzed cycloaddition of furan to 1‐cyanovinyl (1′S)‐camphanate or 1‐cyanovinyl (1′R)‐camphanate led to optically pure (1R,2S,4R)‐2‐exo‐cyano‐7‐oxabicyclo[2.2.1]‐hept‐5‐en‐2‐yl (1S')‐camphanate and (1S,2R,4S)‐2‐exo‐cyano‐7‐oxabicyclo[2.2.1]hept‐5‐en‐2‐yl (1R')‐camphanate, respectively. Saponification afforded (1R,4R)‐ and (1S,4S)‐7‐oxabicyclo[2.2.1]‐hept‐5‐en‐2‐one, respectively, and allowing recovery of the chiral auxiliaries (1S)‐ and (1R)‐camphanic acid, respectively. The 7‐oxabicyclo[2.2.1]hept‐5‐en‐2‐yl derivatives (”naked sugars“) so‐obtained can be substituted at C(3), C(5) and C(6) by direct techniques with high stereoselectivity. The methods exploit the exo‐facial selectivity of the reactions of these bicyclic systems and the regiochemical control exerted by the remote substituents at C(2) in electrophilic attack at C(5) and C(6). The polysubstituted 7‐oxabicyclo[2.2.1]heptan‐2‐ones so‐obtained are chirons that can be converted into D‐ or L‐hexose derivatives and analogues, into 2,5‐anhydrohexonic acid derivatives (precursors for C‐nucleosides and C‐glycosides), or into polysubstituted cyclohex‐1‐ones. Moreover, conditions have been found under which the bicyclic ethers can transformed into (+) and (−)‐methyl 8‐epinonactate and (+)‐ and (−)‐methyl nonactate (precursors of nonactine), into octoses, into branched carbohydrates such as calditoses and calditols, and into (+)‐castanospermine. Compared with natural carbohydrates, the ”naked sugars“ are chirons with the following advantages: (1) the problem of selective protection and deprotection of polyalcoholic systems does not exist; (2) the functional moieties are grafted onto C(3), C(5), and C(6) of the 7‐oxabicyclo[2.2.1]heptane systems together with the appropriate protective groups; (3) since both enantiomeric forms of the ”naked sugars“ an available, either enantiomers of a targeted compound can be reached with the equal ease.
The Sampling of Ions from an Atmospheric‐Pressure Flame into a Vacuum Chamber
Authors: Axford S. D. T. , Hayhurst A. N. 
Published: September 2010

AbstractOne atmospheric‐pressure flame of H2 + O2 + N2 has been burnt with a final temperature of 2400 K. Small amounts of caesium were added to the burner supplies, which resulted in free electrons and Cs−+ ions being formed in the flame. The burnt gases were continuously sampled through a tiny (diam. 80 ‐ 200 μm) orifice at the tip of a hollow conical nozzle. Subsequently the gases pass inside the nozzle and down a conical expansion duct into a vacuum chamber. A pointed needle is located axially inside the hollow sampling nozzle and collects either the positively or negatively charged species which had passed through the inlet hole to the vacuum chamber. It was found that, for optimal sampling of negative ions, the sampling nozzle should be at a positive potential with respect to the burner. However, the sampling of positive ions from a flame is best achieved when the burner and nozzle are at the same potential. The effect of varying the inlet orifice's diameter is also investigated. All the observations can be explained in terms of there being either an ion or an electron sheath adjacent to the sampling nozzle. Moreover, the thickness of such a sheath varies inversely with the square root of the electron density in the flame. One important conclusion is that when the electron concentration is low, it is usually impossible for electrons to pass through the inlet hole; instead they are collected by the sampling nozzle. However, for large electron densities (∼ 10−10/ml) and a big orifice, electrons can pass through the sampling hole into the vacuum chamber. By contrast the losses of positive or negative ions, whether atomic or molecular, are almost negligible.
Effect of Temperature on the Fragmentation Pattern of Hydrocarbons Under Electronic Impact
Authors: Walravens B. , Vandooren J. , Tiggelen P. J. Van 
Published: September 2010

AbstractThe study shows the change induced by the temperature of sampling on the fragmentation pattern of n‐butane and isobutane when a molecular beam sampling technique is used coupled with a mass spectrometric analysis. A decrease of the parent peak signal of both butane isomers is observed when the sampling temperature increases. Furthermore, sampling temperature effects on the parent peak of some hydrocarbons from C1 up to C4 have also been investigated.
Étude expérimentale de flammes méthane oxygène dopées avec de l'ammoniac ou du monoxyde d'azote comparaison avec les résultats des modèles
Authors: Garo A. , Puechberty D. 
Published: September 2010

AbstractIn order to simulate the formation of NO from fuel Nitrogen and to have a better understanding of the interaction between nitric oxide with hydrocarbon radicals, NH3 and NO have been added to methane oxygen premixed flame established under low pressure.Formation and destruction of NO have been studied from experimental results obtained using mass spectrometry, U.V. optical absorption spectroscopy and L.I.F. measurements. Modeling of these flames is performed with Miller s kinetic mechanism and with a modified one. Thus it is possible to deduce the relative importance of NO reactions with hydrocarbon radicals in the first millimeters of the flame.
The Solubility of Calcium Hydrogen Phosphate Dihydrate and Magnesium Hydrogen Phosphate Trihydrate and Ion Pair Formation in the System M(OH)2‐H3Po4‐H2O (M = Ca or Mg) at 37°C
Authors: De Bruyne Peter A. M. , Verbeeck Ronald M. H. , Verbeek Frans 
Published: September 2010

AbstractThe solubility of CaHPO4·2H2O and MgHPO4·3H2O is determined in the system M(OH)2‐H3PO4‐H2O at 37°C with M = Ca or Mg and in the range 4.1 < pH < 6.3 and 4.9 < pH < 7.2 respectively. The solubility behaviour of both solids can be described consistently only by taking into account the formation of the ion pairs MH2PO4+ and MHPO4. The thermodynamic solubility product of CaHPO4·2H2O and the thermodynamic association constants for CaH2PO4 + and CaHPO4 with their standard error are determined as (2.06 ± 0.05)×10−7 mol2/L2, 8.4 ± 1.7 L/mol and 542 ± 46 L/mol. The corresponding constants for MgHPO4·3H2O, MgH2PO4 + and MgHPO4 are (1.15 ± 0.07)×106 mol2/L2, 43.0 ± 6.7 L/mol and 1004 ± 89 L/mol.
Mechanism of the Polarographic Reduction of Anti‐5‐Nitro‐2‐Furaldoxime
Authors: López Fonseca J. M. , García Monteagudo J. C. , Crespo M. A. , Lois B. 
Published: September 2010

AbstractThe electroreduction of the radiosensitizer anti‐5‐nitro‐2‐furaldoxime (nifuroxime) was studied by conventional, normal pulse and reversed pulse polarography in aqueous buffers containing 0.75% dimethylformamide. In acid media were obtained four cathodic waves, namely I (related to the reduction with 4 electrons of the nitro group), II and III (both linked to the reduction of the oxime group with 4 electrons) and IV (corresponding to the reduction of the hydroxylamino group formed in the reaction yielding wave I). As the pH increased, IV disappeared, II and III overlapped and I was split into waves I' and I“. Mechanisms accounting for the electrode processes of the waves are proposed. The presence of sodium laurylsulphate decreased the limiting current of I' to 1/4 of that of I; under these conditions, wave I' corresponded to the reversible reduction of the nitro derivative to its radical‐anion.
One Pot N‐Protection of Amino Acids
Authors: Becu Chr. , Reyniers M.‐F. , Anteunis M. J. O. , Callens R. 
Published: September 2010

AbstractAttention is called on the extreme simple procedure for N‐protection of amino acids mediated through previous silylation. Although the methodology is known, it has rather scarcely been used. Some examples show the versatility of a one‐pot procedure. Selective Boc and Z‐ Nα‐protections of His were also worked out.
Synthesis and Characterization of DMSO and HMPA Adducts of R′OCOCHRCH2SnCl3
Authors: Fu Fangxin , Tian Laijin , Pan Huade , Willem Rudolph , Gielen Marcel 
Published: September 2010

AbstractThe synthesis and characterization of complexes of R'OCOCHRCH2SnCl3 with DMSO and HMPA by means of elemental analysis, IR, Mössbauer, 1H and 13C NMR spectroscopy are described.
Crystal Structure of 2,3‐Diamino‐2,3‐Diphenylbutane
Authors: Bracke B. , Volckaerts E. , Lenstra A. T. H. , Geise H. J. 
Published: September 2010

AbstractC16H20N2, M = 240.35, monoclinic, P21/n, a = 6.800(1), b = 6.833(2), c = 14.427(2)Å,β = 97.55(1)°, V = 664.5(4)Å)−3, Z = 2, Dx = 1.202 g cm−3, μ = 1.33 cm−1, λ(Mo‐Kα) = 0.71073Å, F(000) = 520, room temperature, R = 0.079, wR = 0.080 for 113 variables and 499 observed [I ≥ 3σ(I)] reflections of 1575 measurements.The structure of this new compound is proved and its configuration established as meso. The large sterical hindrance in the central part of the molecule is reflected in an unusually long central C‐C bond (1.635(7)Å). It explains why in the mass spectrum under electron impact the molecular ion peak [M+] is missing and the peak at half the molecular weight [1/2M+] has a high abundance.
Synthesis of Soluble Poly(Divinylbenzene) with an End‐Functional Group
Authors: Nagasaki Yukio , Kato Masao , Kato Norikiyo , Mitsuhata Yoshio , Nishizuka Hiroaki , Tsuruta Teiji 
Published: September 2010

AbstractSynthetic methods of end‐functional soluble poly(divinylbenzene) [poly(DVB)] and A‐B‐A type block copolymers having soluble poly(divinylbenzene) segments were investigated. Lithium N,N′‐bis(trimethylsilyl) ethylenediamine was found to initiate an anionic polymerization of 1,4‐divinylbenzene (DVB) to form soluble polymer having one N,N′‐bis (trimethylsilyl) ethylenediamine moiety at the end of polymer chain almost quantitatively. The polymer was easily converted to primary‐amino‐ended soluble poly(DVB) by treating with tetrabutylammonium fluoride. Lithiated trimethylallylsilane also had an initiation ability for DVB polymerization. When the polymerization was carried out by lithiated trimethylallylsilane, in the presence of diisopropylamine, a soluble polymer was formed. The polymer obtained had one terminal organosilyl group and reactive pendent vinyl group in each monomeric unit. A‐B‐A Type tri‐block copolymer was synthesized through reactions between primary‐amino‐ended soluble poly (DVB) and α,ω‐bis‐primary‐amino‐ended silicone using 4,4′‐diphenylmethanediisocyanate as coupling agent. The resulting polymer was a multi‐functional polymer having poly (DVB) segments and silicone segments.
Hydrophobic ‐ Hydrophilic Copolymers from Functional Organosiloxane Oligomers
Authors: Simionescu C. I. , Harabagiu V. , Giurgiu D. , Hamciuc V. , Simionescu B. C. 
Published: September 2010

AbstractHydrophobic ‐ hydrophilic siloxane containing copolymers were synthesized by two different methods, namely a) radical polymerization of methacrylic acid or N‐vinylpyrrolidone initiated by azo containing polydimethylsiloxanes, and b) radical polymerization of methacrylic acid in the presence of glycidoxypropyl functional polydimethylsiloxanes with simultaneous ring opening reaction by the carboxylic groups.
Contribution of Block Copolymers to the Control of Polymeric Surfaces
Authors: Petitjean S. , Ghitti G. , Fayt R. , Teyssie Ph. , Jerome R. 
Published: September 2010

AbstractDiblock copolymers of polystyrene and polydimethylsiloxane, and polystyrene end‐capped with a fluorinated group have been prepared by anionic polymerization. Polymethylmethacrylate end‐capped with the same fluorinated group has been synthesized by a telomerization technique. Surface activity of all these compounds has been studied in solution by tensiometry and in a polymeric matrix by various methods: XPS and measurements of wettability and contact angle. The relative interactions of the dispersion medium with each component of the additive are of a prime importance in the control of the surface energy.
Thermal Analysis and Small‐Angle X‐Ray Scattering of Homogeneous Copolymers of Ethene and 1‐Octene
Authors: Peeters Marleen , Reynaers Harry 
Published: September 2010

AbstractHomogeneous copolymers of ethene and 1‐octene with a random distribution of comonomer units and the same comonomer/ethene ratio exhibit a double melting behaviour which is ascribed to a slight sample heterogeneity. On crystallization part of the material is segregated and crystallizes on aging of the samples. The results of small‐angle X‐ray experiments allow to correlate the morphological changes and the melting behaviour with the chain microstructure of the copolymer.
Synthetic Approaches for Thymopentin (TP‐5) Using the “in Situ” Silylation Strategy with Trimethylsilyl Cyanide
Authors: Becu Fr. , Becu Chr. , Anteunis M. J. O. 
Published: September 2010

AbstractThe synthesis of the pentapeptide TP‐5 has been considered as a test case for the “in situ” silylating strategy, using trimethylsilyl cyanide, because of the nature of the involved residues. Thus orthogonal lateral protections for Arg, Lys & Asp are needed even using our earlier developed “PERSIL” strategy (5). The best approach was found in a Head‐to‐Tail assemblage of Boc‐Asp(Bzl)‐Val‐Tyr and after Nα deprotection followed by segment condensation with Boc‐Arg(NOG2)‐Lys(Z)‐OPiv and a final two‐step deprotection (SCHEME I). The total yield (38 %) is modest but the relative simplicity for isolation and high quality of the end product (with no detectable epimerization) is noteworthy.
Action Des Composes β‐Dicarbonyles Sur Le Diamino‐5,6 Indazole
Authors: Benchidmi M. , Essassi E. M. 
Published: September 2010

AbstractThe condensation of β‐dicarbonyl compounds with 5,6‐diaminoindazole in hot butanol leads to pyrazolo[4,5‐f]benzimidazole, 5(1‐phenylvinyl)pyrazolo[4,5‐f]benzimidazolone‐6 and 4‐phenyl pyrazolo[3,4‐h][1,5]benzodiazepin‐2‐one.