bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foliage and ground spiders respond differently to a semi‐natural habitat‐vineyard gradient
Authors: Pompozzi G. , Copperi S. , Fernández Campón F. , Lagos Silnik S. , Alzugaray B. , Albrecht E. , Roig‐Juñent S. 
Published: April 2024

AbstractNatural vegetation in and around crops effectively increases predators. Semi‐natural habitats (SNHs; non‐crop vegetation) surrounding crops provide refuge and resources. However, the function of SNHs may depend on several factors, and the response of natural predators may vary among crops and regions. Here, we examined the spider community in a SNH and at an adjacent vineyard in a semi‐arid region of Argentina. We collected spiders in a gradient from an adjacent SNH, towards the vineyard at three distances from the SNH using two techniques: beating and pit‐fall traps. We collected spiders in December and February during two consecutive years at two strata: in vegetation and on the ground. In vegetation, spider abundance significantly decreased from SNH towards the interior of the vineyard at 80 m. On the ground, spider abundance was also significantly higher in SNH. However, after decreasing at the 5 and 20 m sites inside the vineyard, the abundance increased at 80 m. For foliage spiders, species richness followed the same pattern as abundance, whereas ground spider richness significantly increased from SNH to the interior of the vineyard. Species composition also showed different tendencies between foliage and ground spiders. The foliage spider community differed between SNH vs. all the vineyard sites. Contrarily, at the ground stratum, SNH was similar in composition to the edge of the vineyard, and they both differed from the other vineyard sites. We found that the adjacent SNH influenced the spider community in the vineyard and that this effect depended on the distance from that habitat and the association of the community to various strata. These results highlight the importance of studying the whole community of spiders when aiming to increase predator abundance to enhance biological control in this kind of crop. In addition, we found species that may act as indicators of native vegetation which has important implications for the management of natural habitats in this region.
Changing from disease‐centred to person‐centred – Swedish dental hygienists' views on a theory‐based behavioural intervention for improved oral hygiene among adolescents
Authors: Dimenäs Sandra L. , Jönsson Birgitta , Lundin Mona , Lundgren Jesper , Abrahamsson Kajsa H. 
Published: April 2024

AbstractObjectivesTo explore dental hygienists' (DHs') views on (i) a person‐centred, theory‐based, behavioural intervention for improving oral hygiene among adolescents and (ii) professional and organizational factors to consider in the implementation of such an intervention in daily dental practice.MethodsSemi‐structured interviews were conducted with 13 DHs who had applied the person‐centred, theory‐based, behavioural intervention directed at adolescents with poor oral hygiene in a field study within the Public Dental Service, Region Västra Götaland, Sweden. The interviews were audio‐taped, transcribed verbatim and analysed using qualitative content analysis.ResultsThe main theme ‘From individual experts to partners – DHs changing direction from a disease‐centred towards a person‐centred approach’ illustrated a changed professional approach among DHs, from exerting their roles as experts to encouraging partnership in treatment by supporting the adolescents in taking health behavioural decisions and responsibility for their oral health. The DHs considered the changed approach as challenging, but also more enjoyable, compared to conventional information/instruction. Adequate knowledge and skills, personal interest and willingness for a change as well as support from colleagues and clinic management were identified as prerequisites for implementing the person‐centred, theory‐based, behavioural intervention in daily practice, while the expenditure of time needed in relation to economic demands in care were seen as barriers.ConclusionsThe findings elucidate that DHs considered the application of a person‐centred, theory‐based, behavioural intervention to be challenging but also enjoyable. For such an intervention to be implemented in daily practice, prerequisites and barriers need to be considered on both personal/professional and organizational levels.
Erythritol powder airflow for the treatment of peri‐implant mucositis: A randomized controlled clinical trial
Authors: Corbella Stefano , Radaelli Katherine , Alberti Alice , Francetti Luca , Taschieri Silvio 
Published: April 2024

AbstractObjectivesPeri‐implant mucositis is a biofilm‐related, reversible inflammatory disease that can evolve into peri‐implantitis if not adequately treated. The aim of the present randomized controlled clinical trial was to evaluate the efficacy of air‐abrasive powder as compared to chlorhexidine (CHX) for the treatment of peri‐implant mucositis, in terms of clinical and patient‐reported outcomes (PROMs) and occurrence of peri‐implantitis 12 months after treatment.MethodsIn the control group, full‐mouth calculus and plaque removal was performed with ultrasound and manual devices, and a 1.0% CHX gel was applied; in the test group, supra‐ and subgingival biofilm removal was performed using erythritol powder with a dedicated nozzle and calculus removal was performed with ultrasonic instruments if needed. Bleeding and plaque indexes, peri‐implant probing depth and tissue level were measured at 1 week, and 1, 3, 6 and 12 months after treatment, while PROMs were evaluated up to 7 days after treatment.ResultsAmong 80 included implants, 70 were analysed at 12 months follow‐up (30 in the test group, 40 in the control group, and 20 subjects). Success rates (implant‐level) in terms of bleeding index were significantly different between the test (96.7%) and control group (92.5%); as for PROMs, only taste sensation was significantly better in the test group. The test group was significantly correlated to the smallest changes in peri‐implant probing depth between baseline and 3 months.ConclusionsThe study showed that both treatment strategies are effective. This suggests that the use of air‐abrasive powders could be used as an alternative biofilm removal method instead of adjunctive treatments with antiseptics.
Consumer responses toward smart technology: A systematic review, synthesis, and future research agenda
Authors: Sağkaya Güngör Ayşegül , Ozansoy Çadırcı Tuğçe , Köse Şirin Gizem , Özer Çizer Ece 
Published: April 2024

AbstractThis article is a comprehensive review of the literature on smart technology in consumer studies from 1996 to 2023. While the paper provides information about the development of the field by identifying important publications and authors, it employs topic modeling to pinpoint key topics in papers published in marketing and business journals. These topics are then grouped into three research streams and evaluated concerning theoretical, contextual, and methodological perspectives. While doing so, specific gaps were identified. By revealing gaps in the literature, the study suggests promising avenues for further research. Finally, this article advances our comprehension of the smart technology literature in marketing and business journals and informs future inquiry in this rapidly evolving domain.
Preceptor's experience in supervising undergraduate nursing students in mental health: A qualitative study
Authors: Benny Jessy , Porter Joanne E. , Joseph Bindu 
Published: April 2024

AbstractPreceptorship is considered an essential component in undergraduate nursing student's clinical placement, especially those in speciality units such as mental health. During the preceptorship relationship students are granted the opportunity to work alongside experienced nurses in the ward observing their interactions with patients and other professionals. In addition, students are able to build clinical confidence and competence. There is currently a gap in the literature around the preceptorship experience in the mental health clinical environment which warrants further exploration. The aim of this study was to explore the experiences of Registered Nurses precepting undergraduate nursing students during mental health clinical placements. A qualitative, exploratory approach was performed. A total of eight registered nurses working in an acute in‐patient mental health unit in a large regional hospital, were recruited and interviewed using a semi‐structured interview technique. Thematic analysis was utilised to analyse the data resulting in the development of four overarching themes; (1) Time consuming and additional workload, (2) creating a safe environment, (3) providing and receiving feedback and (4) precepting is not a choice, it is an expectation. The results highlighted that preceptoring students was considered to be an extra workload that required significant time and effort. Preceptors also expressed concerns about student safety, emphasised the importance of feedback and acknowledged preceptorship as an expectation of registered nurses working in mental health. These findings underscore the necessity for further research to delve deeper into the experience of preceptors in mental health settings.
Cartilage stem/progenitor cells‐derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model
Authors: Chen Jing , Ni Xiaohui , Yang Jian , Yang Hongwei , Liu Xiaoyu , Chen Minhao , Sun Cheng , Wang Youhua 
Published: April 2024

AbstractCartilage defects in the knee are often associated with the progression of degenerative osteoarthritis (OA), and cartilage repair is a useful strategy for managing this disease. However, cartilage repair is challenging because of the unique environment within the tissue. Recently, stem cell‐based therapies have shed new light on this issue. In this study, we prepared exosomes (EXOs) from cartilage stem/progenitor cells (CSPCs) and found that treatment with EXOs increased the viability, migration, and proliferation of cultured primary chondrocytes. In a subacute OA rat model, the application of EXOs facilitated cartilage regeneration as evidenced by histological staining. Exosomal protein analysis together with bioinformatics suggested that cyclin‐dependent kinase 9 (CDK9) is a key factor for chondrocyte growth and migration. Functional studies confirmed this prediction, that is, inhibiting CDK9 reduced the beneficial effects induced by EXOs in primary chondrocytes; while overexpression of CDK9 recapitulated the EXOs‐induced phenotypes. RNA‐Seq data showed that a set of genes involved in cell growth and migration were up‐regulated by EXOs in chondrocytes. These changes could be partially reproduced by CDK9 overexpression. Overall, our data suggest that EXOs derived from primary CSPCs hold great therapeutic potential for treating cartilage defect‐associated disorders such as degenerative OA, and that CDK9 is a key factor in this process.
Probing the salivary proteome for prognostic biomarkers in response to non‐surgical periodontal therapy
Authors: Silbereisen Angelika , Bao Kai , Wolski Witold , Nanni Paolo , Kunz Laura , Afacan Beral , Emingil Gülnur , Bostanci Nagihan 
Published: April 2024

AbstractAimThis prospective study investigated the salivary proteome before and after periodontal therapy.Materials and MethodsTen systemically healthy, non‐smoking, stage III, grade C periodontitis patients underwent non‐surgical periodontal treatment. Full‐mouth periodontal parameters were measured, and saliva (n = 30) collected pre‐ (T0), and one (T1) and six (T6) months post‐treatment. The proteome was investigated by label‐free quantitative proteomics. Protein expression changes were modelled over time, with significant protein regulation considered at false discovery rate <0.05.ResultsTreatment significantly reduced bleeding scores, percentages of sites with pocket depth ≥5 mm, plaque and gingival indexes. One thousand seven hundred and thirteen proteins were identified and 838 proteins (human = 757, bacterial = 81) quantified (≥2 peptides). At T1, 80 (T1 vs. T0: 60↑:20↓), and at T6, 118 human proteins (T6 vs. T0: 67↑:51↓) were regulated. The salivary proteome at T6 versus T1 remained stable. Highest protein activity post‐ versus pre‐treatment was observed for cellular movement and inflammatory response. The small proline‐rich protein 3 (T1 vs. T0: 5.4‐fold↑) and lymphocyte‐specific protein 1 (T6 vs. T0: 4.6‐fold↓) were the top regulated human proteins. Proteins from Neisseria mucosa and Treponema socranskii (T1 vs. T0: 8.0‐fold↓, 4.9‐fold↓) were down‐regulated.ConclusionsPeriodontal treatment reduced clinical disease parameters and these changes were reflected in the salivary proteome. This underscores the potential of utilizing saliva biomarkers as prognostic tools for monitoring treatment outcomes.
Comorbidities, mortality and metabolic profile in individuals with primary biliary cholangitis—A Phenome‐Wide‐Association‐Study
Authors: Koop Paul‐Henry , Schwenzer Constanze , Clusmann Jan , Vell Mara S. , Jaeger Julius , Gui Wenfang , Trautwein Christian , Koch Alexander , Bruns Tony , Schneider Carolin V. , Schneider Kai Markus 
Published: April 2024

AbstractBackground and AimsPrimary biliary cholangitis (PBC) is a chronic, immune‐mediated liver disease that can lead to fibrosis and cirrhosis. In this cohort study, we aimed to investigate morbidity and mortality in conjunction with metabolomic changes of PBC in a UK population‐based cohort.Methods454 participants with PBC and 908 propensity score (age, sex, BMI, ethnicity) matched controls without liver disease were included in the study. A subset of participants with PBC and controls were analysed for their metabolomic profile. Further, PBC‐associated comorbidities were investigated by PheWAS analysis. Lastly, we assessed causes of death in individuals with PBC using a Fine and Grey competing‐risks regression model.ResultsCompared to the control group, various pathways associated with the metabolism of amino acids, lipids, and liver biochemistry were significantly enriched in individuals with PBC. We found reduced levels of S‐HDL‐cholesterol and Glycoprotein Acetyls in individuals with PBC as well as an association with diseases of the circulatory system. Notably, PBC individuals had a higher prevalence of digestive diseases, autoimmune diseases, cardiovascular diseases, anaemias, mental disorders, and urinary tract infections compared to the control group. Strikingly, the overall mortality was almost three times higher in the PBC group compared to the control group, with diseases of the digestive system accounting for a significant elevation of the death rate. A subsequent analysis, enhanced by propensity score matching that included the APRI score, demonstrated that the observed morbidity could not be exclusively attributed to advanced hepatic disease.ConclusionsOur study provides a detailed perspective on the morbidity of individuals with PBC. The exploration of potential effects of disease state on morbidity suggest that early detection and early treatment of PBC could enhance patient prognosis and prevent the onset of comorbid diseases. Finally, the metabolomic alterations could represent a link between the pathophysiological processes underlying PBC development, progression, and associated morbidity.
Multistage charging facility planning on the expressway coordinated with the power structure transformation
Authors: Zhang Tian‐yu , Yao En‐jian , Yang Yang , Yang Hong‐Ming , Guo Dong‐bo , Wang David Z. W. 
Published: April 2024

AbstractThis study presents a novel multistage expressway fast charging station (EFCS) planning problem coordinated with the dynamic regional power structure (PS) transformation. Under the prerequisite of the EFCS network's sustainable operation, network accessibility, and orderly construction, a three‐step planning method oriented to the enhancement of energy saving and emission reduction (ESER) benefits and rationalization of facility utilization is developed: (i) EV‐expanded network, (ii) multiagent‐based dynamic traffic assignment (MA‐DTA), and (iii) deployment refinement. Embedding the MA‐DTA and customized refinement strategy into the iterative planning structure enables the integration of operations and planning of the EFCS network. A numerical experiment and an empirical study in the Shandong Peninsula urban agglomeration are conducted. It demonstrates that the method can find a high‐quality solution within acceptable computation time and is applicable to realistic large‐scale EFCS planning. The planning method can effectively play the role of economy and facility in inducing EV users' charging demands, thus enhancing the overall ESER benefits. The integration of operation and planning is proven effective in reasonably matching the supply and demand of facility service and charging loads in a full‐time period. Further, the multistage EFCS planning schemes during 2025–2045 are explored, and some insightful policy implications are revealed.
Safety of catheter ablation in patients with recently implanted cardiac implantable electronic device: A 5‐year experience
Authors: Toquica Christian , Jazayeri Mohammad‐Ali , Noheria Amit , Berenbom Loren , Emert Martin , Pimentel Rhea , Dendi Raghu , Reddy Y. Madhu , Sheldon Seth H. 
Published: April 2024

AbstractIntroductionCatheter ablation (CA) can interfere with cardiac implantable electronic device (CIED) function. The safety of CA in the 1st year after CIED implantation/lead revision is uncertain.MethodsThis single center, retrospective cohort included patients who underwent CA between 2012 and 2017 and had a CIED implant/lead revision within the preceding year. We assessed the frequency of device/lead malfunctions in this population.ResultsWe identified 1810 CAs in patients between 2012 and 2017, with 170 CAs in 163 patients within a year of a CIED implant/lead revision. Mean age 68 ± 12 years (68% men). Time between the CIED procedure and CA was 158 ± 99 days. The CA procedures included AF ablation (n = 57, 34%), AV node ablation (n = 40, 24%), SVT ablation (n = 37, 22%), and PVC/VT ablations (n = 36, 21%). The cumulative frequency of lead dislodgement, significant CIED dysfunction, and/or CIED‐related infection following CA was (n = 1/170, 0.6%). There was a single atrial lead dislodgement (0.6%). There were no instances of power‐on‐reset or CIED‐related infection. Following CA, there was no significant difference in RA or RV lead sensing (p = 0.52 and 0.84 respectively) or thresholds (p = 0.94 and 0.17 respectively). The RA impedance slightly decreased post‐CA from 474 ± 80 Ohms to 460 ± 73 Ohms (p = 0.002), as did the RV impedance (from 515 ± 111 Ohms to 497 ± 98 Ohms, p < 0.0001).ConclusionsCA can be performed within 1 year following CIED implantation/lead revision with a low risk of CIED/lead malfunction or lead dislodgement. The ideal time to perform CA after a CIED remains uncertain.
Mno‐miR164a and MnNAC100 regulate the resistance of mulberry to Botrytis cinerea
Authors: Wang Donghao , Chen Lin , Liu Chaorui , Wang Hairui , Liu Zixuan , Ji Xianling , He Ningjia , Xin Youchao 
Published: April 2024

AbstractAlthough microRNAs (miRNAs) regulate the defense response of a variety of plant species against a variety of pathogenic fungi, the involvement of miRNAs in mulberry's defense against Botrytis cinerea has not yet been documented. In this study, we identified responsive B. cinerea miRNA mno‐miR164a in mulberry trees. After infection with B. cinerea, the expression of mno‐miR164a was reduced, which was fully correlated with the upregulation of its target gene, MnNAC100, responsible for encoding a transcription factor. By using transient infiltration/VIGS mulberry that overexpressed mno‐miR164a or knocked‐down MnNAC100, our study revealed a substantial enhancement in mulberry's resistance to B. cinerea when mno‐miR164a was overexpressed or MnNAC100 expression was suppressed. This enhancement was accompanied by increased catalase (CAT) activity and reduced malondialdehyde (MDA) content. In addition, mno‐miR164a‐mediated inhibition of MnNAC100 enhanced the expression of a cluster of defense‐related genes in transgenic plants upon exposure to B. cinerea. Meanwhile, MnNAC100 acts as a transcriptional repressor, directly suppressing the expression of MnPDF1.2. Our study indicated that the mno‐miR164a‐MnNAC100 regulatory module manipulates the defense response of mulberry to B. cinerea infection. This discovery has great potential in breeding of resistant varieties and disease control.
The European Pillar of Social Rights: How strategic agency shaped the European Union's flagship social initiative
Authors: Dura Sophie 
Published: April 2024

AbstractThe European Pillar of Social Rights sits at the fulcrum of EU social policymaking. This article aims to explore its legal and political character, how it was shaped in the adoption process and its place within Social Europe. The key argument is that the Social Pillar builds on but also critically modifies previous initiatives present within the broader EU governance framework, notably in the European Semester. Key political actors like Commission President Jean‐Claude Juncker and parliamentary rapporteur Maria João Rodrigues contributed to the adoption process not only through their long‐held political views but also by bringing to bear their own critical reflections on previous EU initiatives. Methodologically, the article relies on 15 interviews with policy experts and uses an interdisciplinary approach based on legal analysis, process tracing and actor‐centred constructivist theory. The contribution of the article is threefold: (1) it helps to better understand the EU's social flagship initiative and the modifications of its governance approach compared with previous initiatives, (2) it sheds new light on the tensions and opportunities of social policymaking within the EU and (3) it shows the added value of actor‐centred constructivist approaches on a theoretical level.
Q negatively regulates wheat salt tolerance through directly repressing the expression of TaSOS1 and reactive oxygen species scavenging genes
Authors: Yang Ziyi , Yang Ruizhen , Bai Wanqing , Chen Wenxi , Kong Xiuying , Zhou Yun , Qiao Weihua , Zhang Yunwei , Sun Jiaqiang 
Published: April 2024

SUMMARYThe Q transcription factor plays important roles in improving multiple wheat domestication traits such as spike architecture, threshability and rachis fragility. However, whether and how it regulates abiotic stress adaptation remain unclear. We found that the transcriptional expression of Q can be induced by NaCl and abscisic acid treatments. Using the q mutants generated by CRISPR/Cas9 and Q overexpression transgenic lines, we showed that the domesticated Q gene causes a penalty in wheat salt tolerance. Then, we demonstrated that Q directly represses the transcription of TaSOS1‐3B and reactive oxygen species (ROS) scavenging genes to regulate Na+ and ROS homeostasis in wheat. Furthermore, we showed that wheat salt tolerance protein TaWD40 interacts with Q to competitively interfere with the interaction between Q and the transcriptional co‐repressor TaTPL. Taken together, our findings reveal that Q directly represses the expression of TaSOS1 and some ROS scavenging genes, thus causing a harmful effect on wheat salt tolerance.