bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Intermolecular Morita—Baylis—Hillman Reactions Using Dicobalthexacarbonyl Complexed Acetylenic Acetals.
Authors: Krafft Marie E. , Campbell Mark J. , Kerrigan Sean , Cran John W. 
Published: April 2011

AbstractTreatment of Co‐complexes (I) with BF3·OEt2 generates stabilized cationic intermediates which react with activated alkenes (II) to provide coupling products (III) after decomplexation.
ChemInform Abstract: First Synthesis of Bromo and Chloro Derivatives of Baylis—Hillman Adducts Derived from Nitroolefins: Application Towards the Synthesis of a Dendrimer Core.
Authors: Bakthadoss Manickam , Sivakumar Nagappan , Devaraj Anthonisamy 
Published: April 2011

AbstractTreatment of nitrolefins with aqueous formaldehyde results in formation of nitropropenols which undergo SN2 reactions with HBr and FeCl3 to afford the title compounds.
ChemInform Abstract: Asymmetric Hydrogenation of N‐Alkyl Ketimines with Phosphine‐Free, Chiral, Cationic Ru‐MsDPEN Catalysts.
Authors: Chen Fei , Wang Tianli , He Yanmei , Ding Ziyuan , Li Zhiwei , Xu Lijin , Fan Qing‐Hua 
Published: April 2011

AbstractA wide range of N‐alkyl imines is efficiently hydrogenated under mild conditions using a chiral Ru catalyst in the presence of Boc2O to give the corresponding N‐Boc‐protected amines in excellent enantioselectivity (up to 98% e.e.).
ChemInform Abstract: Synthesis, Antimicrobial Activity and Structure—Activity Relationship Study of N,N‐Dibenzyl‐cyclohexane‐1,2‐diamine Derivatives.
Authors: Sharma Mukul , Joshi Penny , Kumar Nitin , Joshi Seema , Rohilla Rajesh K. , Roy Nilanjan , Rawat Diwan S. 
Published: April 2011

AbstractSynthesis and antimicrobial activity of a series of structurally diverse diamines (44 examples) are reported.
ChemInform Abstract: Pd(II)‐Catalyzed Decarboxylative Allylation and Heck‐Coupling of Arene Carboxylates with Allylic Halides and Esters.
Authors: Wang Jiantao , Cui Zili , Zhang Yuexia , Li Huajie , Wu Long‐Min , Liu Zhongquan 
Published: April 2011

AbstractThis alternative method provides access to allylated arenes (III) and aryl‐substituted allylic esters (VI)/(VII) via catalytic decarboxylative C—C bond formation using aromatic carboxylic acids (I) and (IV) and allylic halides (II) and esters (V), respectively.
ChemInform Abstract: Elemental Iodine or Diphenyl Diselenide in the [Bis(trifluoroacetoxy)iodo]benzene‐Mediated Conversion of Alkynes into 1,2‐Diketones.
Authors: Tingoli Marco , Mazzella Mauro , Panunzi Barbara , Tuzi Angela 
Published: April 2011

AbstractThe transformation of alkynes (I) into α‐diketones (II) proceeds smoothly in the system PIFA—diphenyl diselenide.
ChemInform Abstract: Copper‐Catalyzed Aerobic Oxidative Synthesis of Aromatic Carboxylic Acids.
Authors: Yang Daoshan , Yang Haijun , Fu Hua 
Published: April 2011

AbstractAn efficient and practical method for the synthesis of aromatic carboxylic acids (21 examples) from corresponding aryl halides is developed using sequential Ullmann‐type coupling with malononitrile, aerobic oxidation and hydrolysis.
ChemInform Abstract: Asymmetric Synthesis of α‐Aryl Amino Acids: Aryne‐Mediated Diastereoselective Arylation.
Authors: Jones Elizabeth P. , Jones Peter , Barrett Anthony G. M. 
Published: April 2011

AbstractCoupling of the pyrazine (I) with arynes, generated in situ, followed by pyrazine ring cleavage allows access to various enantiomerically enriched α‐arylglycines.
ChemInform Abstract: A Mild and Efficient Palladium‐Catalyzed Cyanation of Aryl Chlorides with K4[Fe(CN)6].
Authors: Yeung Pui Yee , So Chau Ming , Lau Chak Po , Kwong Fuk Yee 
Published: April 2011

AbstractThe mild conditions allow the presence of a wide scope of sensitive functional groups.
ChemInform Abstract: Ruthenium‐Catalyzed Synthesis of 1,5‐Dichlorides by Sequential Intermolecular Kharasch Reactions.
Authors: Thommes Katrin , Fernandez‐Zumel Mariano A. , Buron Charlotte , Godinat Aurelien , Scopelliti Rosario , Severin Kay 
Published: April 2011

AbstractRuthenium‐catalyzed reaction of styrene derivatives (II) with α,α‐dichloro‐malononitrile, ‐malonate or ‐acetonitrile (I) proceeds via a double Kharasch pathway to give symmetrical or unsymmetrical 1,5‐diaryl‐1,5‐dichlorides in good yields.
ChemInform Abstract: Cobalt‐Catalyzed Addition of Styrylboronic Acids to 2‐Vinylpyridine Derivatives.
Authors: Kobayashi Tsuneyuki , Yorimitsu Hideki , Oshima Koichiro 
Published: April 2011

AbstractCobalt‐catalyzed addition of vinylpyridine derivatives to styrylboronic acids results in formation of butenyl heteroarenes.
ChemInform Abstract: Consecutive One‐Pot Sonogashira—Glaser Coupling Sequence — Direct Preparation of Symmetrical Diynes by Sequential Pd/Cu Catalysis.
Authors: Merkul Eugen , Urselmann Dominik , Mueller Thomas J. J. 
Published: April 2011

AbstractSonogashira cross coupling of (het)aryl iodides (I) and (IV) with trimethylsilylacetylene (II) is successfully combined with Glaser coupling using air as oxidant to give symmetrical diaryldiacetylenes (III) and (V), resp., in a two‐step one‐pot sequence.
ChemInform Abstract: Chemoselective Phosphine‐Catalyzed Cascade Annulations Between Two Different Activated Alkenes: Highly Diastereoselective Syntheses of Polysubstituted Cyclohexanes and Cyclopentenes.
Authors: Cai Lingchao , Zhang Bo , Wu Guiping , Song Haibin , He Zhengjie 
Published: April 2011

AbstractCascade [2 + 2 + 2] and [2 + 2 + 1] annulations between 2 molecules of 2‐arylidene cyanoacetates or malononitriles and 1 molecule of α,β‐unsaturated ketones are presented.
ChemInform Abstract: A Biomimetic Iron Catalyst for the Epoxidation of Olefins with Molecular Oxygen at Room Temperature.
Authors: Schroeder Kristin , Join Benoit , Amali Arlin Jose , Junge Kathrin , Ribas Xavi , Costas Miquel , Beller Matthias 
Published: April 2011

AbstractA novel method is developed using air as the oxidant.
ChemInform Abstract: Organocatalytic Asymmetric Direct Vinylogous Aldol Reactions of γ‐Crotonolactone with Aromatic Aldehydes.
Authors: Pansare Sunil V. , Paul Eldho K. 
Published: April 2011

AbstractThe reaction is catalyzed by bifunctional organocatalysts (I) and provides diastereomerically and enantiomerically enriched 5‐substituted 2(5H)‐furanones (IV).
ChemInform Abstract: Site‐Selective Suzuki—Miyaura Cross‐Coupling Reactions of 2,3,4,5‐Tetrabromofuran.
Authors: Hussain Munawar , Khera Rasheed Ahmad , Hung Nguyen Thai , Langer Peter 
Published: April 2011

AbstractProcedures are developed for a selective preparation of mono‐, bis‐ and symmetrical and unsymmetrical tetra‐arylated furan derivatives.
ChemInform Abstract: Efficient Synthesis of Functionalized Butenolides Mediated by Vinyltriphenylphosphonium Salts in Aqueous Media.
Authors: Khalilzadeh Mohammad A. , Hasannia Adel , Baradarani Mohammad M. , Hossaini Zinatossadat 
Published: April 2011

AbstractThe reaction of esters (II) with triphenylphosphine results in formation vinyltriphenylphosphonium salts which react with carbonyl compounds (I) or (IV) to produce highly functionalized butenolides.
ChemInform Abstract: Diastereoselective Hydroformylation of 2,5‐Cyclohexadienyl‐1‐carbinols with Catalytic Amounts of a Reversibly Bound Directing Group.
Authors: Usui Ippei , Nomura Kenichi , Breit Bernhard 
Published: April 2011

AbstractThe bicyclic lactones are interesting building blocks with an alkene function for further conversions.
ChemInform Abstract: Ruthenium‐Catalyzed Oxidative Vinylation of Heteroarene Carboxylic Acids with Alkenes via Regioselective C—H Bond Cleavage.
Authors: Ueyama Takumi , Mochida Satoshi , Fukutani Tatsuya , Hirano Koji , Satoh Tetsuya , Miura Masahiro 
Published: April 2011

AbstractThe procedure provides a new shortcut for vinylindole carboxylic acid derivatives [cf.(XIc)], which exhibit neuroprotective activities.
ChemInform Abstract: Synthesis of Chiral Cyclic Nitrones by Asymmetric Addition of β‐Ketosulfones to Nitroalkenes Followed by Reductive Cyclization.
Authors: Garcia Mancheno Olga , Tangen Pia , Rohlmann Renate , Froehlich Roland , Aleman Jose 
Published: April 2011

AbstractThe addition step is catalyzed by thiourea cinchona alkaloids like (I) to give the sulfone addition products as diastereomeric mixtures.
ChemInform Abstract: Enantioselective Friedel—Crafts Alkylation of Indole Derivatives Catalyzed by New Yb(OTf)3‐Pyridylalkylamine Complexes as Chiral Lewis Acids.
Authors: Grach Guillaume , Dinut Aurelia , Marque Sylvain , Marrot Jerome , Gil Richard , Prim Damien 
Published: April 2011

AbstractComplex (I) is effective in the reaction of indole derivatives with trifluoropyruvate.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Domino Reactions of Formylcyclopropane 1,1‐Diesters: Construction of a 6‐5‐5 Tricyclic Pyrrolo[1,2‐a]indole.
Authors: Li Linxia , Du Ding , Ren Jun , Wang Zhongwen 
Published: April 2011

AbstractAn N‐heterocyclic carbene catalyzed domino ring‐opening/redox amidation/Knoevenagel condensation of indolecarbaldehydes and formylcyclopropanes is reported.
ChemInform Abstract: Synthesis of Dihydropyrano[3,2‐e]indoles as Rotationally Restricted Phenolic Analogues of 5‐Hydroxyindole—Thermal Claisen Approach versus Gold Catalysis.
Authors: Karageorge George N. , Macor John E. 
Published: April 2011

AbstractThe use on a gold catalyst facilitates the Claisen rearrangement/cyclization of propargyloxyindoles (I) allowing to reduce the reaction temperature from 156°C to 101°C with better yields of the condensed heterocycles (II).
ChemInform Abstract: Synthesis of Difluoroaryldioxoles Using BrF3.
Authors: Hagooly Youlia , Welch Michael J. , Rozen Shlomo 
Published: April 2011

AbstractTreatment of catechols with thiophosgene provide the corresponding thiodioxoles which upon treatment with bromine trifluoride produce potentially biologically important difluoroaryldioxoles in good to very good yields.
ChemInform Abstract: Synthesis of 4(5)‐Phenacyl‐imidazoles from Isoxazole Side‐Chain Rearrangements.
Authors: Martorana Annamaria , Piccionello Antonio Palumbo , Buscemi Silvestre , Giorgi Gianluca , Pace Andrea 
Published: April 2011

AbstractThe reaction must be carried out under nitrogen atmosphere in deoxygenated solvent to prevent the oxidation of the imidazole products.
ChemInform Abstract: VO(acac)2‐Catalyzed Condensation of o‐Phenylenediamine with Aromatic Carboxylic Acids/Aldehydes under Microwave Radiation Affording Benzimidazoles.
Authors: Dey Madhudeepa , Deb Krishnajyoti , Dhar Siddhartha Sankar 
Published: April 2011

AbstractAdvantages of the method are high conversion, short reaction time and solvent‐free conditions.
ChemInform Abstract: Direct Arylation of Benzothiazoles and Benzoxazoles with Aryl Boronic Acids.
Authors: Ranjit Sadananda , Liu Xiaogang 
Published: April 2011

AbstractDirect arylation of benzothiazole (IV) and benzoxazole (I) with a wide range of arylboronic acids is smoothly achieved in the presence of a Pd—Cu cocatalyst under aerobic conditions.
ChemInform Abstract: Copper(I) 1,2,3‐Triazol‐5‐ylidene Complexes as Efficient Catalysts for Click Reactions of Azides with Alkynes.
Authors: Nakamura Tatsuhito , Terashima Takahiro , Ogata Kenichi , Fukuzawa Shin‐ichi 
Published: April 2011

AbstractStarting from triazoles, various copper‐aNHC complexes are prepared.
ChemInform Abstract: A New Palladium(II)‐Catalyzed [3,3] Aza‐Claisen Rearrangement of 3‐Allyloxy‐5‐aryl‐1,2,4‐oxadiazoles.
Authors: Fontana Gianfranco , Piccionello Antonio Palumbo 
Published: April 2011

AbstractSubstituted derivatives such as (Ib,c) react with very high degree of stereochemistry explained by a cationic palladacycle intermediate similar to the one postulated for the Cope‐rearrangement of 1,5‐dienes.
ChemInform Abstract: Synthesis, Antihypertensive Activity, and 3D‐QSAR Studies of Some New p‐Hydroxybenzohydrazide Derivatives.
Authors: Bhole Ritesh P. , Bhusari Kishore P. 
Published: April 2011

AbstractA variety of new thiadiazole (V) and thiazole derivatives (IX) are synthesized starting from p‐hydroxybenzohydrazide (I).
ChemInform Abstract: Intramolecular Hydroalkoxylation in Broensted Acidic Ionic Liquids and Its Application to the Synthesis (.+‐.)‐Centrolobine (XXIb).
Authors: Jeong Yunkyung , Kim Do‐Young , Choi Yunsil , Ryu Jae‐Sang 
Published: April 2011

AbstractThe novel ionic liquids (I)—(III) are similarly effective in initial studies, but (Ia) and (II) are more effective in large‐scale reactions.
ChemInform Abstract: Gold(I)‐Catalyzed Access to Tetrahydropyran‐4‐ones from 4‐(Alkoxyalkyl)oxy‐1‐butynes: Formal Catalytic Petasis—Ferrier Rearrangement.
Authors: Bae Hyo Jin , Jeong Wook , Lee Ji Hyung , Rhee Young Ho 
Published: April 2011

AbstractSubstituted tetrahydropyranones are synthesized by the new method including a gold(I)‐catalyzed cycloisomerization which represents a catalytic alternative of the Petasis—Ferrier rearrangement.
ChemInform Abstract: Highly Enantioselective Conjugate Addition of Cyclic Diketones to β,γ‐Unsaturated α‐Ketoesters Catalyzed by an N,N′‐Dioxide—Cu(OTf)2 Complex.
Authors: Dong Zhenhua , Feng Juhua , Fu Xuan , Liu Xiaohua , Lin Lili , Feng Xiaoming 
Published: April 2011

AbstractTitle reaction provides access towards hexahydrobenzopyrans in high yields and excellent enantioselectivities (up to 99% e.e.).
ChemInform Abstract: In vitro Antiproliferative Activity of Benzopyranone Derivatives in Comparison with Standard Chemotherapeutic Drugs.
Authors: Musa Musiliyu A. , Cooperwood John S. , Khan M. Omar F. , Rahman Taufiq 
Published: April 2011

AbstractIn vitro results indicate that compounds (Ia)‐(Id) are more potent than tamoxifen against some human breast cancer cell lines.
ChemInform Abstract: Highly Efficient and Green Synthesis of 14‐Aryl(alkyl)‐14H‐dibenzo[a,j]xanthene and 1,8‐Dioxooctahydroxanthene Derivatives Catalyzed by Reusable Zirconyl Triflate [ZrO(OTf)2] under Solvent‐Free Conditions.
Authors: Mohammadpoor‐Baltork Iraj , Moghadam Majid , Mirkhani Valiollah , Tangestaninejad Shahram , Tavakoli Hamid Reza 
Published: April 2011

AbstractThe method for the synthesis of xanthene derivatives is advantageous with regard to a very short reaction time, high yield, and operational simplicity.
ChemInform Abstract: Synthesis of 14‐Aryl or Alkyl‐14H‐dibenzo[a,j]xanthenes Promoted by Mg(HSO4)2.
Authors: Mirjalili Bi Bi Fatemeh , Bamoniri Abdolhamid , Akbari Ali 
Published: April 2011

AbstractThe Mg(HSO4)2‐catalyzed condensation of 2‐naphthol with aldehydes can be carried out under neat conditions or in methylene chloride using ultrasound irradiation to give the title compounds in excellent yields.
ChemInform Abstract: Synthesis of Diisothiocyanato‐Functionalized 2,2′‐Bipyridines.
Authors: Kremer Christopher , Luetzen Arne 
Published: April 2011

AbstractDiaminobipyridines such as (I) and (IV) are prepared by known three‐step sequence and converted into the corresponding diisothiocyanato derivatives upon treatment with thiophosgene.
ChemInform Abstract: 2‐Substituted‐2,3‐dihydro‐1H‐quinolin‐4‐ones via Acid‐Catalyzed Tandem Rupe Rearrangement—Donnelly—Farrell Ring Closure of 2‐(3′‐Hydroxypropynyl)anilines.
Authors: Pisaneschi Federica , Sejberg Jimmy J. P. , Blain Cecile , Ng Wang Hei , Aboagye Eric O. , Spivey Alan C. 
Published: April 2011

Abstractortho‐Amino substituted internal arylalkynes of type (III) are prepared by Sonogashira coupling.
ChemInform Abstract: Scandium(III) Zeolites as New Heterogeneous Catalysts: [4 + 2]Cyclocondensation of in situ Generated Aryl Imines with Alkenes.
Authors: Olmos Andrea , Sommer Jean , Pale Patrick 
Published: April 2011

AbstractA ligand‐free catalyst is used for the cyclocondensation of amines and aldehydes with alkenes via in situ formation of imines.
ChemInform Abstract: Preparation of Benzolactams by Pd(II)‐Catalyzed Carbonylation of N‐Unprotected Arylethylamines.
Authors: Lopez Blanca , Rodriguez Aleix , Santos David , Albert Joan , Ariza Xavier , Garcia Jordi , Granell Jaume 
Published: April 2011

AbstractAn unprecedented NH2‐directed Pd(II)‐catalytic carbonylation of quaternary aromatic α‐amino esters produces 6‐membered benzolactams.
ChemInform Abstract: Iodine‐Catalyzed Formation of Aza‐Dienes: A Novel Synthesis of Angularly Fused Hexahydropyrano‐ and Furo[3,2‐c]quinoline Derivatives.
Authors: Reddy B. V. Subba , Grewal Harish 
Published: April 2011

AbstractThe reaction provides an efficient access to quinoline derivatives of potential biological relevance.
ChemInform Abstract: N,N′‐Dichlorobis(2,4,6‐trichlorophenyl)urea (CC‐2) as a New Reagent for the Synthesis of Pyrimidone and Pyrimidine Derivatives via Biginelli Reaction.
Authors: Rao G. B. Dharma , Acharya B. N. , Verma S. K. , Kaushik M. P. 
Published: April 2011

AbstractThe diarylurea is found to be an efficient reagent for the three‐component coupling of β‐ketoesters, aldehydes, and urea or thiourea to give pyrimidine derivatives (IV).
ChemInform Abstract: Silica‐Bonded N‐Propylsulfamic Acid as a Recyclable Catalyst for the Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones.
Authors: Niknam Khodabakhsh , Jafarpour Nasrolah , Niknam Ebrahim 
Published: April 2011

AbstractThe catalyst is successfully applied to the three‐component condensation reaction.
ChemInform Abstract: Two‐Step Synthesis of 1,3‐Disubstituted 3,4‐dihydro‐4‐thioxoquinazolin‐2(1H)‐ones from 1‐Bromo‐2‐fluorobenzenes.
Authors: Kobayashi Kazuhiro , Komatsu Toshihide , Yokoi Yuki , Konishi Hisatoshi 
Published: April 2011

AbstractBenzothioamides (III) undergo addition—substitution with phenyl isocyanate (IV) to give the desired thioxoquinazolinones (Va)‐(Vc) in good yields.
ChemInform Abstract: Probing the Stereoselectivity of P‐Glycoprotein—Synthesis, Biological Activity and Ligand Docking Studies of a Set of Enantiopure Benzopyrano[3,4‐b][1,4]oxazines.
Authors: Jabeen Ishrat , Wetwitayaklung Penpun , Klepsch Freya , Parveen Zehida , Chiba Peter , Ecker Gerhard F. 
Published: April 2011

AbstractSome of the title benzopyranooxazines and their precursors (I)/(II), e.g. (Ib), (Ic), (IIb), (IIc), and (IIIc) demonstrate significant P‐glycoprotein inhibitory activity.
ChemInform Abstract: Gold‐Catalyzed Tandem Intramolecular Heterocyclization/Petasis—Ferrier Rearrangement of 2‐(Prop‐2‐ynyloxy)benzaldehydes as an Expedient Route to Benzo[b]oxepin‐3(2H)‐ones.
Authors: Sze Ella Min Ling , Rao Weidong , Koh Ming Joo , Chan Philip Wai Hong 
Published: April 2011

AbstractUniquely, ring formation only proceeds efficiently in the presence of a gold catalyst.
ChemInform Abstract: HF‐Free, Direct Synthesis of Tetrabutylammonium Trifluoroborates.
Authors: Prakash G. K. Surya , Pertusati Fabrizio , Olah George A. 
Published: April 2011

AbstractThe synthesis of the target compounds from boronic acids and bifluoride (II) is advantageous with regards to safety and tolerability towards substrate functionality.
ChemInform Abstract: A General Synthetic Method for 1,1′‐Bis(diacetylene‐group)‐Connected Ferrocene and π‐Electronic System.
Authors: Yoshino Junro , Shimizu Rumi , Hayashi Naoto , Higuchi Hiroyuki 
Published: April 2011

AbstractUnder modified Eglinton oxidative coupling conditions, it is possible to generate 1,1′‐diethynylferrocene in situ from a trimethylsilyl‐protected precursor (I) and to react it with other terminal alkenes (III).
ChemInform Abstract: Neojaponicone A, a Bioactive Sesquiterpene Lactone Dimer with an Unprecedented Carbon Skeleton from Inula japonica.
Authors: Qin Jiang Jiang , Wang Li Yan , Zhu Jia Xian , Jin Hui Zi , Fu Jian Jun , Liu Xiao Feng , Li Hong Lin , Zhang Wei Dong 
Published: April 2011

AbstractCompound (I) has an unprecedented carbon skeleton with an unusual valerolacton system formed between a guaianolide and an eudesmane.
ChemInform Abstract: A Powerful Synergistic Effect for Highly Efficient Diastereo‐ and Enantioselective Phase‐Transfer Catalyzed Conjugate Additions.
Authors: Hua Ming‐Qing , Wang Lian , Cui Han‐Feng , Nie Jing , Zhang Xiao‐Ling , Ma Jun‐An 
Published: April 2011

AbstractA novel dinuclear N‐spiroammonium salt is prepared and successfully used as chiral catalyst in the conjugate addition of ester (II) to enones (I).
ChemInform Abstract: Highly Regio‐ and Stereoselective One‐Pot Synthesis of Carbohydrate‐Based Butyrolactones.
Authors: Yousuf Syed Khalid , Mukherjee Debaraj , L Malikharjunrao , Taneja Subhash C. 
Published: April 2011

AbstractThe method has the potential to generate libraries for biological screening.
ChemInform Abstract: CeCl3·7H2O: A Versatile and Efficient Reagent for the Synthesis of C‐Pyrrolyl Glycosides.
Authors: Reddy Basi V. Subba , Jain Ruchi , Bhargavi Kudikyala , Swain Manisha , Yadav Jhillu S. 
Published: April 2011

AbstractA simple procedure allows the synthesis of pharmacologically important title compounds (IV) and (VI) via coupling of D‐glucosamine with 1,3‐diketones and β‐keto esters followed by acetylation.
ChemInform Abstract: Synthesis and Biological Evaluation of New 4β‐Anilino‐4′‐O‐demethyl‐4‐desoxypodophyllotoxin Derivatives as Potential Antitumor Agents.
Authors: Wang Li , Yang Fenyan , Yang Xiaochun , Guan Xianghong , Hu Chunqi , Liu Tao , He Qiaojun , Yang Bo , Hu Yongzhou 
Published: April 2011

AbstractThe title podophyllotoxin analogues are evaluated for their cytotoxicities against four human cancer cell lines including KB, KB/VCR, A549, and 95D.
ChemInform Abstract: Synthesis of a Novel Ester of Hydroxytyrosol and α‐Lipoic Acid Exhibiting an Antiproliferative Effect on Human Colon Cancer HT‐29 Cells.
Authors: Bernini Roberta , Crisante Fernanda , Merendino Nicolo , Molinari Romina , Soldatelli Maria Chiara , Velotti Francesca 
Published: April 2011

AbstractCompound (I) induces a considerably strong block of the tumor cell cycle in the G2/M phase.
ChemInform Abstract: Synthetic Analogues of Daidzein, Having More Potent Osteoblast Stimulating Effect.
Authors: Yadav Dinesh K. , Gautam Abnish K. , Kureel Jyoti , Srivastava Kamini , Sahai Mahendra , Singh Divya , Chattopadhyay Naibedya , Maurya Rakesh 
Published: April 2011

AbstractThe structure of daidzein is modified to achieve an improved osteogenic effect and to eliminate uterine estrogenicity.
ChemInform Abstract: New Hedgehog/GLI Signalling Inhibitors from Excoecaria agallocha.
Authors: Rifai Yusnita , Arai Midori A. , Sadhu Samir K. , Ahmed Firoj , Ishibashi Masami 
Published: April 2011

AbstractTwo new compounds (I) and (II) and six known flavonoid glycosides are isolated from the methanolic extract of the leaves of E.
Asymmetric anionic polymerization of 2,7‐bis(4‐t‐butylphenyl)fluoren‐9‐ylmethyl methacrylate and photoinduced structural transition of the obtained polymer
Authors: Watanabe Kento , Sakamoto Takeshi , Nakano Tamaki 
Published: April 2011

Abstract2,7‐Bis(4‐t‐butylphenyl)fluoren‐9‐ylmethyl methacrylate (BBPFMMA) was synthesized as a new candidate of a bulky monomer suitable for asymmetric anionic polymerization (IUPAC nomenclature: asymmetric helix‐chirogenic polymerization) leading to a preferred‐handed helical, optically active polymer. The new monomer was polymerized using the complex of 9‐fluorenyllithium and (S)‐(+)‐1‐(2‐pyrrolidinylmethyl)pyrrolidine in toluene at −78°C. As opposed to the original intention to obtain a polymethacrylate, the monomer seemed to undergo structural transition (decomposition) giving 2,7‐bis(4‐t‐butylphenyl)dibenzofulvene and the obtained polymer was most probably a terpolymer of BBPFMMA, 2,7‐bis(4‐t‐butylphenyl)dibenzofulvene, and methacrylic acid. The obtained polymer showed circular dichroism (CD) spectra, indicating that chirality had been introduced to the copolymer chain during the course of polymerization. On photo irradiation, the polymer underwent a structural transition involving a remarkable decrease in apparent molecular weight measured by size‐exclusion chromatography (SEC) and changes in FT‐IR spectral patterns. However, the CD spectrum of the polymer was not obviously altered by irradiation, indicating that polymer chirality is not affected by light. Chirality, 2011. © 2011 Wiley Periodicals, Inc.