bluuebunny/crossref_metadata_2025_split huggingface dataset:
IFF/SSR rectangular patch antenna with reduced transversal size
Authors: Zieniutycz Wlodzimierz , Mazur Mateusz , Pergol Mariusz 
Published: December 2010

AbstractMicrostrip antenna for IFF/SSR systems fed by H‐shaped coupling slot is presented in this article.Due to application of H‐shaped slot about 36% reduction of transversal dimension of antenna is obtained as compared to rectangular slot use. Such reduction is desired if the antenna is used in circular array especially on the cylindrical surface. The results of simulations are compared to the results of measurement of fabricated antenna. The antenna shows good parameters: VSWR < 1.5, crosspolar to copolar < −30 dB in both planes, gain > 7 dBi. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:451–455, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25740
A concurrent triple‐band CMOS low noise amplifier for fourth generation applications
Authors: Jang Yohan , Choi Jaehoon 
Published: December 2010

AbstractIn this study, a concurrent triple‐band low noise amplifier (LNA) is designed for long term evolution (LTE), Mobile‐WiMAX (M‐WiMAX), and WiMAX services. The main topology of the proposed LNA is a cascode architecture with source degeneration using shunt resistive feedback topology for the triple‐resonance characteristic. The LNA is designed using a Taiwan Semiconduction Company (TSMC) 0.18 μm radio frequency CMOS process. To obtain the necessary gains over the operating frequency bands, a series LC branch is added in parallel with an inductor at the drain load of a single band LNA. The peak gains at LTE, M‐WiMAX, and WiMAX bands are 17.6, 14.7, and 14.5 dB, respectively, whereas dissipating 8 mA from a 1.4 V supply voltage. The average noise figure over the three operating frequency bands is 4.5 dB. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:415–418, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25743
Small‐size printed strip MIMO antenna for next generation mobile handset application
Authors: Han Minseok , Choi Jaehoon 
Published: December 2010

AbstractA compact printed multiple‐input multiple‐output (MIMO) antenna with an embedded chip inductor is proposed for a 4G mobile handset application. The proposed MIMO antenna consists of a longer strip with an embedded chip inductor and a shorter radiating strip. The longer radiating strip with a 15‐nH embedded chip inductor has a length of only about 42 mm (∼ 0.1 wavelength at 0.77 GHz), but it supports a wide resonant mode at 0.77 GHz for long‐term evolution (LTE) Band 13 and at 2.35 GHz for WiBro operation. The shorter radiating strip has a length of about 15 mm (about 0.1 wavelength at 2.0 GHz) and provides a wide resonant mode at about 2 GHz for WCDMA operation. The two radiating strips occupy a small printed area of about 720 mm2 on the system circuit board of a mobile handset. The proposed MIMO antenna has an isolation of approximately −17 dB at LTE band 13 and the envelope correlation coefficient (ECC) of the two antennas is always lower than 0.4 over the whole LTE band 13. To evaluate the performance of the proposed antenna, key performance parameters such as the total efficiency, ECC, mean effective gain (MEG), and the MEG ratio are analyzed. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:348–352, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25746
A multiband‐rejected UWB monopole antenna using interdigital defected ground structure
Authors: Lee Jae‐Kwan , Kim Young‐Sik 
Published: December 2010

AbstractIn this letter, a compact ultra wideband (UWB) circular monopole antenna with multi‐bandstop characteristics is proposed. An interdigital defected ground structure (IDDGS) etched under the feed line of the proposed antenna is utilized. This UWB antenna has multiple stop bands, which are 2.10–3.80 GHz (WCDMA), 5.30–5.90 GHz (WLAN), 7.65–7.90 GHz, and 9.55–9.75 GHz. An IDDGS yields multiple resonances and the length of an IDDGS affects an antenna resonant frequency. Simulated and measured results show good agreement in the proposed antenna. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:312–314, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25748
Double‐cavity fiber Fabry‐Perot tunable filter
Authors: Jiang Yi , Tang Caijie , Wang Chong‐Wen 
Published: December 2010

AbstractA double‐cavity fiber Fabry‐Perot tunable filter is proposed and experimentally demonstrated. There are two cavities in the tunable filter. The two cavities have close properties, and are driven by same piezoelectric transducers. One cavity is used to scan wavelength, and another one is used to calibrate the wavelength. The double‐cavity filter is anticipated to be used to interrogate not only the spectra of passive components, but also that of active light sources. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:242–245, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25752
The role of teacher quality in retention and hiring: Using applications to transfer to uncover preferences of teachers and schools
Authors: Boyd Don , Lankford Hamp , Loeb Susanna , Ronfeldt Matthew , Wyckoff Jim 
Published: December 2010

AbstractMany large urban school districts are rethinking their personnel management strategies, often giving increased control to schools in the hiring of teachers, reducing, for example, the importance of seniority. If school hiring authorities are able to make good decisions about whom to hire, these reforms have the potential to benefit schools and students. Prior research on teacher transfers uses career history data, identifying the school in which a teacher teaches in each year. When such data are used to see which teachers transfer, it is unclear the extent to which the patterns are driven by teacher preferences or school preferences, because the matching of teachers to schools is a two‐sided choice. This study uses applications‐to‐transfer data to examine separately which teachers apply for transfer and which get hired and, in so doing, differentiates teacher from school preferences. Holding all else equal, we find that teachers with better pre‐service qualifications (certification exam scores, college competitiveness) are more likely to apply for transfer, while teachers whose students demonstrate higher achievement growth are less likely. On the other hand, schools prefer to hire “higher quality” teachers across measures that signal quality. The results suggest that not only do more effective teachers prefer to stay in their schools but that schools are able to identify and hire the best candidates when given the opportunity © 2010 by the Association for Public Policy Analysis and Management.
Long‐term results of AIEOP‐8805 protocol for acute B‐cell lymphoblastic leukemia of childhood
Authors: Pillon Marta , Aricò Maurizio , Basso Giuseppe , Locatelli Franco , Citterio Marco , Micalizzi Concetta , Testi Anna Maria , Barisone Elena , Nardi Margherita , Lombardi Alessandra , Rondelli Roberto , Rosolen Angelo ,   On behalf of the NHL‐Committee of the Italian Association of Pediatric Hematology, Oncology (AIEOP)
Published: December 2010

AbstractBackgroundAcute B‐cell leukemia (B‐ALL) is a rare form of pediatric leukemia characterized by a very high‐proliferation index, rapid clinical progression, and a high frequency of central nervous system (CNS) involvement. Commonly, it is treated in the clinical trials for Burkitt lymphoma, of which it represents the leukemic counterpart.ProcedureChildren with B‐ALL diagnosed between 1988 and 1999 were enrolled in the AIEOP‐8805 protocol. Treatment included six high‐dose chemotherapy courses. No prophylactic CNS irradiation was administered.ResultsSixty‐five consecutive patients were enrolled in the study. L3 morphology was observed in 57 of 65 patients (88%). Twenty‐five children (38%) had tumor mass in addition to massive bone marrow infiltration; 11 children (17%) had CNS disease at diagnosis. Sixty‐two patients obtained complete morphological remission of which 13 suffered a relapse, including 3 with initial CNS involvement. Ten‐year overall survival and event‐free survival were 77% and 75%, respectively. Neither relevant long‐term toxicity nor second malignancies were observed.ConclusionsThe AIEOP‐8805 confirmed that short high‐dose chemotherapy is highly effective for the treatment of B‐ALL without significant long‐term adverse sequelae. Therapy modifications to reduce relapse rate, such as the use of anti‐CD20 monoclonal antibody and more effective CNS treatment, are being tested. Pediatr Blood Cancer 2011;56:544–550. © 2010 Wiley‐Liss, Inc.
Protein and peptide fractionation, enrichment and depletion: Tools for the complex proteome
Authors: Ly Linda , Wasinger Valerie C. 
Published: December 2010

AbstractThe identification, quantitation and global characterisation of all proteins within a given proteome are extremely challenging. This is due to the absolute detection limits of technology as well as the dynamic range in expression of proteins; and the extreme diversity and heterogeneity of the proteome. To overcome such issues, the use of separation technologies has played a critical role in reducing sample complexity. To date, a plethora of chromatographic and electrophoretic fractionation tools have evolved over the years assisting in simplifying complex protein and peptide mixtures. Here, we review a range of these technologies highlighting the challenges of protein and peptide analysis in the context of proteome research and some of the advantages and disadvantages of present techniques.
Protein expression profiling in chemical carcinogenesis: A proteomic‐based approach
Authors: Schmitz‐Spanke Simone , Rettenmeier Albert W. 
Published: December 2010

AbstractThe simultaneous analysis of a wide array of proteins may provide valuable information on the activation and suppression of cellular systems at different stages of the exposure‐disease continuum. In this review, results of proteomic studies in the field of toxicology are covered, focusing on the effects of chemical carcinogens. So far, alterations of highly abundant proteins have been identified which, irrespective of the wide differences in study design and technologies used, can be grossly assigned to three functional classes: proteins related to cellular stress response, inflammation, and stimulation of the immune system. It is obvious that the observed protein alterations are not causal factors in the development of chemically induced cancer but rather reflect common reactions to cellular perturbations. In order to gain deeper insights into the process of chemical carcinogenesis, the previously applied “shotgun” analyses have to be abandoned in favour of targeted proteomic approaches focusing on the accurate identification and quantification of selected proteins. Advanced analytical techniques such as selective reaction monitoring (SRM) and multiple reaction monitoring (MRM) offer this opportunity. If toxicoproteomic research moves into that direction and takes advantage of such techniques it will have the potential to contribute to the elucidation of chemical carcinogenesis.
Discussion on common data analysis strategies used in MS‐based proteomics
Authors: Matthiesen Rune , Azevedo Luisa , Amorim Antonio , Carvalho Ana Sofia 
Published: December 2010

AbstractCurrent proteomics technology is limited in resolving the proteome complexity of biological systems. The main issue at stake is to increase throughput and spectra quality so that spatiotemporal dimensions, population parameters and the complexity of protein modifications on a quantitative scale can be considered. MS‐based proteomics and protein arrays are the main players in large‐scale proteome analysis and an integration of these two methodologies is powerful but presently not sufficient for detailed quantitative and spatiotemporal proteome characterization. Improvements of instrumentation for MS‐based proteomics have been achieved recently resulting in data sets of approximately one million spectra which is a large step in the right direction. The corresponding raw data range from 50 to 100 Gb and are frequently made available. Multidimensional LC‐MS data sets have been demonstrated to identify and quantitate 2000–8000 proteins from whole cell extracts. The analysis of the resulting data sets requires several steps from raw data processing, to database‐dependent search, statistical evaluation of the search result, quantitative algorithms and statistical analysis of quantitative data. A large number of software tools have been proposed for the above‐mentioned tasks. However, it is not the aim of this review to cover all software tools, but rather discuss common data analysis strategies used by various algorithms for each of the above‐mentioned steps in a non‐redundant approach and to argue that there are still some areas which need improvements.
Understanding and engineering of microbial cells based on proteomics and its conjunction with other omics studies
Authors: Han Mee‐Jung , Lee Jeong Wook , Lee Sang Yup 
Published: December 2010

AbstractThe abilities of microorganisms to produce a wide variety of products ranging from human therapeutics to chemicals and to tolerate or detoxify exogenous stresses such as toxic compounds and pollutants are of great importance in fundamental and applied research. Proteomics has become an indispensable tool for large‐scale protein analyses and can be used to understand the resulting physiological changes and uncover the mechanisms responsible for the cellular processes under various genetic and environmental conditions. Recent development of a multi‐omic approach that combines proteomics with one or more of other omics is allowing us to better understand cellular physiology and metabolism at the systems‐wide level, and consequently paving a way toward more efficient metabolic engineering. In this review, we describe the use of proteomics and its combination with other omics to broaden our knowledge on microorganisms in the field of bioscience and biotechnology. With the increasing interest in practical applications, the strategies of employing proteomics for the successful metabolic engineering of microorganisms toward the enhanced production of desired products as well as the approaches taken to identify novel bacterial components are reviewed with corresponding examples.
Latest Advances in Psychiatry: a reason to be cheerful
Authors: Baldwin David 
Published: December 2010

AbstractIncreased demands but reduced resources. Illusory targets and unrealistic milestones. Short‐term expedience rather than long‐term vision. Such is the pressured environment for those working within mental health services in the UK in 2010. How good it is, therefore, to find something to celebrate. Clearly, the Latest Advances in Psychiatry symposia cannot reverse these fundamental problems, but they do offer some respite: a chance to address personal Continuing Professional Development (CPD) objectives, to listen to experts at the top of their field, to catch up with colleagues, and to cherish the brief time away from the hurly‐burly of psychiatric practice. Copyright © 2010 Wiley Interface Ltd
Young Minds
Authors: Smith Hannah 
Published: December 2010

AbstractYoungMinds is a UK charity committed to improving the emotional wellbeing and mental health of children and young people and empowering their parents and carers. Hannah Smith, Senior Media and Campaigns Officer at YoungMinds, outlines the work the charity is doing to help young people with mental health problems and ensure their wellbeing. Copyright © 2010 Wiley Interface Ltd
International League Against Epilepsy
Authors: Thomas Rhys 
Published: December 2010

AbstractBrighton – famous for its piers, ideas and pioneers – played host to the annual International League Against Epilepsy (ILAE) UK Chapter meeting in October. Here, Dr Rhys Thomas, Clinical Lecturer in Neurology at Cardiff and Swansea University, provides an overview of the highlights of the meeting. Copyright © 2010 Wiley Interface Ltd
Development of the Psycho‐social Discomfort Scale (PsDS): investigation of psychometric properties among Japanese breast cancer survivors
Authors: Tsuchiya Miyako , Horn Sandra , Ingham Roger 
Published: December 2010

AbstractObjective: To develop a new scale to assess psycho‐social discomfort in breast cancer (BC) survivors in Japanese society and to investigate its psychometric properties.Method: A total of 248 Japanese BC survivors completed both the Psycho‐social Discomfort Scale (PsDS) and WHO Quality of Life BREF Japanese version (WHO QoL‐Jp). A principal component factor analysis (with promax rotation) was performed, and internal consistency was examined using Cronbach's alpha. Divergent and convergent validities and criterion validity were examined using the Spearman's R.Results: The factor analysis extracted three factors: ‘internalised stigma (IS)’, ‘social disclosure of BC (SD)’, and ‘psychological resources to live with BC (PR)’. The factors were moderately correlated. The scale had good internal consistency (alpha = 0.80). All sub‐scales were inversely correlated with all the domains in the WHO QoL‐Jp (r = −0.09 to −0.47). BC stage was significantly correlated with the SD sub‐scale, and type of surgery was significantly correlated with the IS sub‐scale.Conclusions: The PsDS has 25 items. It measures psycho‐social discomfort that Japanese BC survivors experienced or were experiencing in their community. It has a simple factor structure, relatively good internal consistency, and a satisfactory divergent validity. Copyright © 2010 John Wiley & Sons, Ltd.
Antitumor and immunoregulatory effects of astragalus on nasopharyngeal carcinoma In Vivo and In Vitro
Authors: Song Yan , Yang Jing , Bai Wei‐liang , Ji Wen‐yue 
Published: December 2010

AbstractThis study was carried out to evaluate the effects of Astragalus on human nasopharyngeal carcinoma (NPC) viability and apoptosis and to investigate the mechanism of Astragalus in a NPC cell line (CNE2). Cell viability was measured using the MTT assay. CNE2 cells treated with Astragalus were stained with acridine orange/ethidium bromide and subjected to fluorescence microscopy. Bcl‐2, Bax, caspase‐3 and ‐8 were measured by western blotting. Rat NPC cells were used to establish a NPC model. Tumor weight, immune organ index and T lymphocyte subsets were employed to detect the immunoregulatory and antitumor effects of Astragalus after administration. Astragalus was effective in inducing apoptosis in CNE2 cells. Morphological changes associated with cell injury were found. Western analysis showed caspase‐3, ‐8, and Bax protein levels were increased after Astragalus treatment, while the bcl‐2 protein level was decreased. Astragalus increased the percentage of CD3+, CD4+ T‐lymphocytes, and the ratio of CD4+/CD8+. Astragalus also restored the immunological effects of DDP‐induced immunosuppression. These findings suggest that the immunomodulatory and anticancer effects of DDP + Astragalus were better than those of DDP alone, and Astragalus could inhibit immunosuppression induced by DDP. The combination of CDDP + Astragalus could be developed as an effective chemotherapeutic regimen in the treatment of nasopharyngeal carcinoma. Copyright © 2010 John Wiley & Sons, Ltd.
A featureless approach to efficient bathymetric SLAM using distributed particle mapping
Authors: Barkby Stephen , Williams Stefan B. , Pizarro Oscar , Jakuba Michael V. 
Published: December 2010

AbstractThis paper presents an approach to simultaneous localization and mapping (SLAM) suitable for efficient bathymetric mapping that does not require explicit identification, tracking, or association of seafloor features. This is accomplished using a Rao–Blackwellized particle filter, in which each particle maintains a hypothesis of the current vehicle state and a grid‐based, two‐dimensional depth map, efficiently stored by exploiting redundancies between different maps. Distributed particle mapping is employed to remove the computational expense of map copying during the resampling process. The proposed approach to bathymetric SLAM is validated using multibeam sonar data collected by an autonomous underwater vehicle over a small‐timescale mission (2 h) and a remotely operated vehicle over a large‐timescale mission (11 h). The results demonstrate how observations of the seafloor structure improve the estimated trajectory and resulting map when compared to dead reckoning fused with ultrashort‐baseline or long‐baseline observations. The consistency and robustness of this approach to common errors in navigation is also explored. Furthermore, results are compared with a preexisting state‐of‐the art bathymetric SLAM technique, confirming that similar results can be achieved at a fraction of the computation cost. © 2010 Wiley Periodicals, Inc.
Knowledge spillovers and strategic entrepreneurship
Authors: Agarwal Rajshree , Audretsch David , Sarkar Mb 
Published: December 2010

AbstractKnowledge spillovers and strategic entrepreneurship has each been the subject of much scholarly attention, but have largely been considered separately rather than in conjunction with each other. In this article, we develop implications of the link between knowledge spillovers and strategic entrepreneurship and identify key topics, themes, and issues for future research. In doing so, we also showcase the articles of the special issue, as they shed light on some unanswered questions and identify additional areas for fruitful research. Copyright © 2010 Strategic Management Society.
A predator–prey model of knowledge spillovers and entrepreneurship
Authors: Parker Simon C. 
Published: December 2010

AbstractKnowledge spillovers are known to generate positive benefits for entrepreneurs, but may come at the expense of knowledge creation by the incumbent firms which generate them. This article develops a predator–prey model of knowledge spillovers which captures the interdependence between idea‐creating incumbents and knowledge spillover‐appropriating entrepreneurs. The values of the model's parameters determine whether these two populations of firms settle down in a stable equilibrium; cycle over time with entrepreneurs doing well when incumbents do badly and vice‐versa; or drive each other to extinction. This sheds light on disparate industry life cycle patterns observed in previous research and generates some novel insights relating to public policy. In particular, the model suggests that governments ought to adopt a dynamic policy stance, initially implementing policies which favor incumbents before shifting their intervention efforts toward encouraging entrepreneurs. Copyright © 2010 Strategic Management Society.
Localized knowledge spillovers and skill‐biased performance
Authors: Gambardella Alfonso , Giarratana Marco S. 
Published: December 2010

AbstractThis article focuses on a relatively unappreciated consequence of localized knowledge spillovers: their implications for productivity across skills. Spillovers benefit skilled workers more than unskilled ones, weaken complementarity between them, and widen their productivity gap. To test this theory, the authors use data from 146 U.S. cities and find that cities with a greater intensity of localized knowledge spillovers exhibit a bigger productivity gap across skills, after controlling for the endogeneity of knowledge spillovers, interindustry differences, and other factors. These results imply that in the long run, economies characterized by localized knowledge spillovers encourage investments in education and attract skilled people, raising the relative share of the skilled population. When complementarity across skills weakens, this analysis also offers a framework to link localized knowledge spillovers to the formation of entrepreneurial skill‐intensive firms. Copyright © 2010 Strategic Management Society.