bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety and efficacy of percutaneous image‐guided ablation for soft tissue sarcoma metastases to the liver
Authors: Awad Ahmed , Pal Koustav , Yevich Steven , Kuban Joshua D. , Tam Alda , Odisio Bruno C. , Gupta Sanjay , Habibollahi Peiman , Bishop Andrew J. , Conley Anthony Paul , Somaiah Neeta , Araujo Dejka M. , Zarzour Maria Alejandra , Ratan Ravin , Roland Christina L. , Keung Emily Z. , Huang Steven Y. , Sheth Rahul A. 
Published: April 2024

AbstractPurposeTo evaluate outcomes following percutaneous image‐guided ablation of soft tissue sarcoma metastases to the liver.Materials and MethodsA single‐institution retrospective analysis of patients with a diagnosis of metastatic soft tissue sarcoma who underwent percutaneous image‐guided ablation of hepatic metastases between January 2011 and December 2021 was performed. Patients with less than 60 days of follow‐up after ablation were excluded. The primary outcome was local tumor progression‐free survival (LPFS). Secondary outcomes included overall survival, liver‐specific progression‐free survival. and chemotherapy‐free survival.ResultsFifty‐five patients who underwent percutaneous ablation for 84 metastatic liver lesions were included. The most common histopathological subtypes were leiomyosarcoma (23/55), followed by gastrointestinal stromal tumor (22/55). The median treated liver lesions was 2 (range, 1–8), whereas the median size of metastases were 1.8 cm (0.3–8.7 cm). Complete response at 2 months was achieved in 90.5% of the treated lesions. LPFS was 83% at 1 year and 80% at 2 years. Liver‐specific progression‐free survival was 66% at 1 year and 40% at 2 years. The overall survival at 1 and 2 years was 98% and 94%. The chemotherapy‐free holiday from the start of ablation was 71.2% at 12 months. The complication rate was 3.6% (2/55); one of the complications was Common Terminology Criteria for Adverse Events grade 3 or higher. LPFS subgroup analysis for leiomyosarcoma versus gastrointestinal stromal tumor suggests histology‐agnostic outcomes (2 years, 89% vs 82%, p = .35).ConclusionPercutaneous image‐guided liver ablation of soft tissue sarcoma metastases is safe and efficacious.
The impact of outpatient supportive oncology on cancer care cost and utilization
Authors: Worster Brooke , Zhu Yifan , Garber Gregory , Kieffer Sawyer , Smith‐McLallen Aaron 
Published: April 2024

AbstractBackgroundSupportive oncology (SO) care reduces symptom severity, admissions, and costs in patients with advanced cancer. This study examines the impact of SO care on utilization and costs.MethodsRetrospective analysis of utilization and costs comparing patients enrolled in SO versus three comparison cohorts who did not receive SO. Using claims, the authors estimated differences in health care utilization and cost between the treatment group and comparison cohorts. The treatment group consisting of patients treated for cancer at an National Cancer Institute‐designated cancer center who received SO between January 2018 and December 2019 were compared to an asynchronous cohort that received cancer care before January 2018 (n = 60), a contemporaneous cohort with palliative care receiving SO care from other providers in the Southeastern Pennsylvania region during the program period (n = 86), and a contemporaneous cohort without palliative care consisting of patients at other cancer centers who were eligible for but did not receive SO care (n = 393).ResultsAt 30, 60, and 90 days post‐enrollment into SO, the treatment group had between 27% and 70% fewer inpatient admissions and between 16% and 54% fewer emergency department visits (p < .05) compared to non‐SO cohorts. At 90 days following enrollment in SO care, total medical costs were between 4.4% and 24.5% lower for the treatment group across all comparisons (p < .05).ConclusionsSO is associated with reduced admissions, emergency department visits, and total costs in advanced cancer patients. Developing innovative reimbursement models could be a cost‐effective approach to improve care of patients with advanced cancer.
The Effectiveness of Silver and Gold in Catalytic Homogenous and Heterogenous Borohydride Hydrolysis – a DFT Study
Authors: Raju Karimadom Basil , Kornweitz Haya 
Published: April 2024

AbstractEnergy demands, and environmental aspects raised the need to study hydrogen‐carrying material such as borohydride for the practical usage of hydrogen as a cleaner and more efficient fuel. A proper understanding of the hydrogen generation mechanism is a key requirement for the designing of efficient catalysts, as the non‐catalytic hydrolysis of borohydride in non‐acidic media is a slow process. The hydrolysis mechanism of borohydride varies considerably using homogeneous and heterogeneous catalysts. A comparison of the hydrolysis mechanism of borohydride using gold and silver as homogenous and heterogeneous catalysts is given in this review. Unexpectedly, with gold catalyst, Au+ or Au(111), only two steps of hydrolysis occur and BH(OH)2 is produced, while with silver catalyst, Ag+ or Ag(111), the hydrolysis can proceed to completion.
Combining text analytics and network path extraction to trace CSR in the social sciences: Intellectual structures and diffusion trajectories
Authors: Yu Dejian , Xiang Bo , Pan Zhuoya 
Published: April 2024

AbstractCorporate social responsibility (CSR) has evolved over time into a mature interdisciplinary scientific field. However, there is a lack of research to explore the disciplinary association patterns and diffusion trajectories of scientific knowledge within this field. This research proposes a knowledge tracing framework that combines text analysis based on scientific texts and main path extraction based on citation networks to fill this gap. This framework is implemented in a dataset containing 15,949 papers related to CSR in the social sciences published from 1969 to 2022. This study identifies 19 main research directions within this field and their five growth trends. Combined with disciplinary categories of publication venues, both the disciplinary origins and disciplinary association patterns of these knowledge contents are also revealed. Besides that, three knowledge diffusion paths are obtained, which meticulously reveal the knowledge evolution and paradigm shift. Aside from the methodological novelty and result scarcity, this study also identifies research streams and potential opportunities. To begin with, CSR‐related studies have shown the tendency of microscopic and interdisciplinary. Then, related research methods show the tendency to be complicated and focus on causal logic. On this basis, some future agendas of CSR are also proposed in this work.
Effect of the Brazilian corporate sustainability index on cash holdings and the moderating role of Covid‐19
Authors: dos Santos Cunha Lucelma Maria , Azevedo Yuri Gomes Paiva , Figueira Laís Manfiolli , de Souza Ribeiro Maisa 
Published: April 2024

AbstractThis study investigates the effect of the Brazilian Corporate Sustainability Index (ISE) on cash holdings and the moderating role of Covid‐19. Our sample comprises 213 non‐financial publicly listed firms from Brazil with 1072 firm‐year observations available on Refinitiv Eikon database from 2015 to 2022. Our overall findings show a positive association between ISE and cash holdings for the entire period analyzed. However, we find that ISE companies retained less cash in the pandemic period. Furthermore, external financial constraint is a channel through which ISE companies tend to lower their levels of cash holdings during the Covid‐19 outbreak. Our main results are robust to alternative measures of cash holdings. Therefore, we contribute to the corporate financial, sustainability, and Covid‐19 literature by providing the first empirical evidence of the dynamic nature of the relationship between ISE and cash holdings during external shocks and further comprehension to investors that sustainable practices reflected on the financial resource strategies are essential information during crises.
Commutation strategy for reduced output voltage ripple in alternative cascaded boost converter
Authors: García‐Vite Pedro Martín , Rebullosa‐Castillo Josué Francisco , García‐Perales Manuel Alejandro , Reyes‐García Brenda Lizeth , García‐Guendulain Crescencio 
Published: April 2024

SummaryWith the rapid penetration of low‐voltage direct current (DC) generators such as photovoltaic panels and storage energy systems, the need for processing energy has propitiated the optimization of power electronics converters. Conventional topologies of power electronics converters have well‐known limitations, mainly due to the parasitic elements and finite commutation times, which do not allow for obtaining a sufficient voltage gain. The literature review has demonstrated that cascade topologies are suited to overcome these limitations. However, to provide a low‐ripple output voltage, they require high values of capacitances. This paper presents an alternative boost converter developed by cascading two power cells. The conventional configuration is slightly modified, producing an alternative power cell. Even though the number of elements is increased, following the suggested commutation strategy, the derived converter can substantially reduce the output voltage ripple. Therefore, capacitors of small value can be employed, avoiding using electrolytic capacitors with shorter life spans than their film counterparts. Besides, given the cascaded connection, the converter possesses a quadratic‐type gain since two independent commanding signals are applied. The different states of commutation are analyzed in depth, allowing the selection of an adequate commutation strategy, which gives the advantage of canceling the output voltage ripple. The mathematical model of the converter is presented and then validated via a scale‐lab prototype. The simulation results evidence the good dynamic performance of the control‐loop design by means of the frequency response analysis.
T‐RESIN: Throughput‐aware dynamic resource orchestration for Internet of Everything‐enabled software‐defined edge networks
Authors: Agrawal Lalita , Mondal Ayan , Obaidat Mohammad S. 
Published: April 2024

SummaryIn this work, we address the problem of resource allocation in Internet of Everything (IoE)‐enabled software‐defined edge networks. In the existing literature, the researchers considered optimizing the performance of the software‐defined networking (SDN) platform using a single‐tier architecture, where the Internet of Things (IoT) devices are in the same tier. However, with the advent of edge computing, we can explore the two‐tier architecture of edge networks—local tier and edge tier—in the presence of SDN, which has not been explored. Hence, we propose an evolutionary game‐based resource allocation scheme for software‐defined edge networks. Additionally, we aim to optimize the QoS of the edge‐based IoE services while optimizing the throughput of the system. The IoT devices use the proposed scheme in the local tier to identify the optimized mapping to the SDN switches. On the other hand, in the edge tier, the proposed scheme aims to optimize the throughput while allocating the IoE service to the optimal subset of edge devices. We evaluated the performance of the proposed scheme using the Python3‐based Mininet platform in the presence of Ryu Controller and Open vSwitches. Ryu is an element‐based software defined networking framework, which offers software elements with well‐described API that enables developers to produce new network control functions. We observed that by using T‐RESIN, the network throughput increases by 27.98%–31.84% than using the existing schemes.
Cytopathology fellowship match: Pros and cons
Authors: Wu Roseann I. , Torous Vanda F. 
Published: April 2024

AbstractA cytopathology fellowship match would create an enforced and structured recruitment timeline for the benefit of applicants and programs. Major benefits would include delaying fellowship applications to allow residents to explore different subspecialty areas, a standardized application process for administrative ease, and optimization of matches between applicants and programs based on ranked preferences rather than use of time‐limited “exploding offers.” The overall gains in efficiency and achieving the primary goals of supporting trainees and recruiting in an equitable and inclusive manner outweigh any downsides to instituting a cytopathology fellowship match. We aim to review the major discussions around this ongoing debate, arriving at the same conclusion as others in the literature that a pan‐pathology fellowship match is ideal and that leadership from the Association of Pathology Chairs will be essential in unifying the fractured fellowship recruitment process.
Prognostic value of growth differentiation factor‐15 in heart failure among whole ejection fraction phenotypes
Authors: Lyu Lyu , Xu Juan , Xv Cui , Xiao Hunan , Liu Zhenzhen , He Yanru , Gao Weiyang , Hao Benchuan , Liu Hongbin 
Published: April 2024

AbstractAimsThe utility of growth differentiation factor‐15 (GDF‐15) in predicting long‐term adverse outcomes in heart failure (HF) patients is not well established. This study explored the relationship between GDF‐15 levels and adverse outcomes in HF patients across various ejection fraction (EF) phenotypes associated with coronary heart disease (CHD) and evaluated the added prognostic value of incorporating GDF‐15 into the Meta‐Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score‐based model.Methods and resultsThis single‐centre cohort study included 823 HF patients, categorized into 230 (27.9%) reduced EF (HFrEF), 271 (32.9%) mid‐range EF (HFmrEF), and 322 (39.1%) preserved EF (HFpEF) groups. The median age was 68.0 years (range: 56.0–77.0), and 245 (29.8%) were females. Compared with the HFrEF and HFmrEF groups, the HFpEF group had a higher GDF‐15 concentration (P = 0.002) and a higher MAGGIC risk score (P < 0.001). We examined the associations between GDF‐15 levels and the risks of all‐cause mortality and HF rehospitalization using Cox regression models. The C‐index, integrated discrimination improvement (IDI), and net reclassification improvement (NRI) metrics were employed to assess the incremental prognostic value. During the 9.4 year follow‐up period, 425 patients died, and 484 were rehospitalized due to HF. Multivariate Cox regression analysis revealed that elevated GDF‐15 levels were significantly associated with an increased risk of all‐cause mortality [hazard ratio (HR) = 1.36, 95% confidence interval (CI): 1.20–1.54; P < 0.001] and HF rehospitalization (HR = 1.75, 95% CI: 1.57–1.95; P < 0.001) across all HF phenotypes. This association remained significant when GDF‐15 was treated as a categorical variable (high GDF‐15 group: all‐cause death: HR = 1.73, 95% CI: 1.40–2.14; P < 0.001; HF rehospitalization: HR = 3.37, 95% CI: 2.73–4.15; P < 0.001). Inclusion of GDF‐15 in the MAGGIC risk score‐based model provided additional prognostic value for all HF patients (Δ C‐index = 0.021, 95% CI: 0.002–0.041; IDI = 0.011, 95% CI: 0.001–0.025; continuous NRI = 0.489, 95% CI: 0.174–0.629) and HF rehospitalization (Δ C‐index = 0.034, 95% CI: 0.005–0.063; IDI = 0.021, 95% CI: 0.007–0.032; continuous NRI = 0.307, 95% CI: 0.147–0.548), particularly in the HFpEF subgroup.ConclusionsGDF‐15 is identified as an independent risk factor for adverse outcomes in HF patients across the entire EF spectrum in the context of CHD. Integrating GDF‐15 into the MAGGIC risk score‐based model enhances its prognostic capability for adverse outcomes in the general HF population. This incremental prognostic effect was observed specifically in the HFpEF subgroup and not in other subgroups.
Intense Photoluminescence and Mechanoluminescence of Novel BaLaAl3O7 : xEu3+ Red Nanophosphors
Authors: Li Chengren , Guo Chunlai , Wang Jianmin , Zhao Fei , Zhang Zhen , Zhao Qianyun , Cui Jinyi 
Published: April 2024

AbstractA series of BaLaAl3O7 : xEu3+ nanophosphors have been prepared by the high‐temperature solid state reaction method. The XRD and SEM characterization results present that there exists a slight influence on the crystal structure and the average particle size of the nanophosphors while the Eu3+ ions are doped into the matrix. The intense and narrow red photoluminescence spectra have been measured under the ultraviolet excitation and there are two optimal Eu3+ concentrations of 0.8 and 12 mol %, respectively, and the intensity of the former is stronger than that of the latter. Furthermore, the mechanoluminescence phenomena with the same color are also observed when the samples are scratched with a pen. The calculated results based on the measurements of thermoluminescence spectra reveal that the total initial concentration of trapped carriers of BaLaAl3O7 : 12Eu3+ nanophosphors is larger than that of BaLaAl3O7 : 0.8Eu3+ sample, which causes the change trend of ML intensity to be opposite to that of PL intensity even though both have the same Eu3+ doping concentrations.
Transition‐Metal‐Free Carbonyl Reduction and Hydrodefluorination of β‐Trifluoromethyl Enones with Hydrosilanes: Synthesis of gem‐Difluorovinyl Alcohols
Authors: Zhang Peng‐Yuan , Hu Ya‐Fei , Chu Jia‐Hao , Zheng Ren‐Jun , Ma Mengtao , Shen Zhi‐Liang , Chu Xue‐Qiang 
Published: April 2024

AbstractA tandem carbonyl reduction and hydrodefluorination of β‐trifluoromethyl enones with hydrosilanes under transition‐metal‐free conditions was developed for the synthesis of a variety of valuable gem‐difluorovinyl alcohols. The hydrosilane could act as both a reductive agent and a C(sp3)‐F bond‐breaking promoter under mild reaction conditions. Synthetically useful organofluorides, such as gem‐fluorophosphine alkene, gem‐difluorovinyl ketone, and fluorinated dihydrofuran derivatives could be readily constructed by further transformations of the obtained gem‐difluorovinyl alcohols. Moreover, the method features mild reaction conditions, operational simplicity, excellent functional group tolerance, and scalability.
Opposites attract? Mixed‐sex parents' and siblings' sport participation differentiates youth athletes' perceived parenting climates
Authors: Chu Tsz Lun (Alan) , Garst Brett J. 
Published: April 2024

AbstractGuided by family systems and achievement goal theories, this study examined how the sex of athletes and their main sport parents, as well as sport participation patterns (same sport, different sports, and no sports) of parent–athlete and sibling sex compositions (same‐sex and mixed‐sex), differentiated athlete perceptions of parenting climates—task‐involving (emphasizing individual improvements, effort, and mastery) and ego‐involving (emphasizing winning and performance comparison). Participants were 353 U.S. high school athletes (Mage = 15.52 and SD = 1.18; 55% male) who completed a survey on perceived parenting climates, family compositions, and sport backgrounds of their parents and siblings. We conducted six moderated regression analyses, two of which used (1) athlete sex and main sport parents' sex, (2) sport participation patterns of parent–athlete sex compositions, or (3) sport participation patterns of sibling sex compositions as independent variables. Four of the analyses were statistically significant with small effect sizes, showing that (1) boys perceived greater ego‐involving climates than girls; (2) athletes whose same‐sex parents played sports (same or different sports) compared to no sports‐perceived greater task‐involving climates: (3) athletes whose mixed‐sex parents played (same or different sports) compared to no sports‐perceived greater task‐involving climates and less ego‐involving climates; and (4) athletes whose mixed‐sex siblings played different sports than they did, compared no sports, and perceived greater task‐involving climates. None of the interactions were significant. Findings provide theoretical and practical implications by incorporating motivational climates, addressing the potential relationships of parents' and mixed‐sex siblings' sport participation to adaptive parenting climates.
Pointwise data depth for univariate and multivariate functional outlier detection
Authors: Jiménez‐Varón Cristian F. , Harrou Fouzi , Sun Ying 
Published: April 2024

AbstractData depth is an efficient tool for robustly summarizing the distribution of functional data and detecting potential magnitude and shape outliers. Commonly used functional data depth notions, such as the modified band depth and extremal depth, are estimated from pointwise depth for each observed functional observation. However, these techniques require calculating one single depth value for each functional observation, which may not be sufficient to characterize the distribution of the functional data and detect potential outliers. This article presents an innovative approach to make the best use of pointwise depth. We propose using the pointwise depth distribution for magnitude outlier visualization and the correlation between pairwise depth for shape outlier detection. Furthermore, a bootstrap‐based testing procedure has been introduced for the correlation to test whether there is any shape outlier. The proposed univariate methods are then extended to bivariate functional data. The performance of the proposed methods is examined and compared to conventional outlier detection techniques by intensive simulation studies. In addition, the developed methods are applied to simulated solar energy datasets from a photovoltaic system. Results revealed that the proposed method offers superior detection performance over conventional techniques. These findings will benefit engineers and practitioners in monitoring photovoltaic systems by detecting unnoticed anomalies and outliers.
Precipitation adjustment by the OTT Parsivel2 in the central Qinghai–Tibet Plateau
Authors: Wang Chong , Zhao Lin , Ma Lu , Hu Guojie , Zhang Lele , Zou Defu , Xing Zanpin , Xiao Yao , Zhou Huayun , Qiao Yongping , Wang Yuanwei , Liu Aili , Xiao Minxuan , Zhao Jianting 
Published: April 2024

AbstractGround observation of precipitation is fundamental in preparing and evaluating various precipitation datasets, which are essential for running hydrologic and climatologic models. The undercatch of traditional precipitation gauges leads to significant uncertainty in ground observation, which is particularly severe in the central Qinghai–Tibet Plateau (QTP). To evaluate the undercatch biases, intercomparison experiments between Geonor T‐200B, the Chinese standard precipitation gauge (CSPG), and OTT Parsivel2 disdrometer were conducted at Tanggula (TGL) and Wudaoliang (WDL) sites. The adjustment schemes for 30‐min and daily precipitation were proposed and applied to 30‐min precipitation at TGL over 10 years and the monthly precipitation of the national meteorological stations on the QTP over 37 years. The results indicated that after adjustment the annual precipitation increased by 49.09% at TGL and 16.41% over the QTP. Snow took up 9.91% of the annual precipitation over the QTP, while it took up over 60% at TGL. Because of the high snow proportion, the central QTP had lower catch ratio and higher adjustment ratio than the QTP average. From 1981 to 2017, the central QTP presented a wetter trend, and the annual precipitation increased by 3.15 mm/yr, higher than the QTP average. Moreover, in the central QTP, precipitation increased more in wet than dry seasons, which were 2.45 and 0.83 mm/yr, respectively. While on the entire QTP, the dry season precipitation increased slightly more than the wet season, which were 0.67 and 0.50 mm/yr, respectively. On the QTP, adjustment amount presented an increasing trend from the northwest to the southeast, whereas annual adjustment ratio was the opposite. This study could enhance the knowledge of precipitation characteristics over the QTP, especially in the central region. More effort will be given to the calibration and uncertainty evaluation of the proposed schemes in future work.