bluuebunny/crossref_metadata_2025_split huggingface dataset:
Membrane Protein Profiling of Human Islets of Langerhans Using Several Extraction Methods
Authors: Hansson Sara F. , Henriksson Åsa , Johansson Lars , Korsgren Olle , Eriksson Jan W. , Tornqvist Hans , Davidsson Pia 
Published: October 2010

Abstract

Introduction
Proteomic characterization of the human pancreatic islets, containing the insulin producing beta-cells, is likely to be of great importance for improved treatment and understanding of the pathophysiology of diabetes mellitus.

Objective
The focus of this study was to characterize the human islet membrane proteome.

Methods
In order to identify as many membrane proteins as possible, five different extraction procedures were used, i.e., phase separation using Triton X-114, a plasma membrane protein kit, cell surface protein biotinylation, total protein extraction, and lipid-based protein immobilization flow cell. Digested protein extracts were analyzed by nanoflow liquid chromatography tandem mass spectrometry. Then the identified proteins were categorized according to cellular location using their gene ontology annotation and by prediction of transmembrane helices in the sequence. This information was used to estimate the amount of membrane proteins identified.

Results
By combining the results from all extraction procedures, the total number of membrane proteins identified from the human islets was increased, accentuating that a combination of methods usually gives a higher coverage of the proteome. A total of 1,700 proteins were identified (≥2 unique peptides), and 735 of these proteins were annotated as membrane proteins while 360 proteins had at least one predicted transmembrane helix. The extraction method using phase separation with Triton X-114 yielded both the highest number and the highest proportion of membrane proteins.

Conclusion
This study gave an enhanced characterization of the human islet membrane proteome which may contribute to a better understanding of islet biology.
Data accuracy on automatic traffic counting: the SMART project results
Authors: Bellucci Patrizia , Cipriani Ernesto 
Published: October 2010

Abstract
In this paper the results of an experimental survey on traffic monitoring devices, named SMART Project, are presented. Aim of the project was to define the requirements to be applied to traffic technologies to match specific applications. The project involved the construction of a test site on a main road, where seven different traffic monitoring systems were installed. A 1 year survey was carried out to assess technologies response to environmental and mechanical solicitations. A reference system specifically devoted to check and validate the devices under test was designed for the project. Test procedures were also developed to control the results achieved. The outcomes accomplished for vehicles counting are described in details in the essay hereunder.
Monotonicity constraints and supercritical Neumann problems
Authors: Serra Enrico , Tilli Paolo 
Published: October 2010

We prove the existence of a positive and radially increasing solution for a semilinear Neumann problem on a ball. No growth conditions are imposed on the nonlinearity. The method introduces monotonicity constraints which simplify the existence of a minimizer for the associated functional. Special care must be employed to establish the validity of the Euler equation.

Résumé
On démontre l'existence d'une solution positive et radialement croissante pour un problème de Neumann semilinéaire sur une boule. Aucune restriction de croissance n'est imposée sur la nonlinéarité. La méthode indroduit des contraintes de monotonie qui simplifient la preuve de l'existence d'un minimum pour la fonctionnelle associée à l'équation. Une attention particulière est consacrée à la preuve de la validité de l'équation d'Euler.
Inherently loyal or easily bored?: Nonconscious activation of consistency versus variety‐seeking behavior
Authors: Fishbach Ayelet , Ratner Rebecca K. , Zhang Ying 
Published: October 2010

AbstractThis article explores nonconscious effects on consumers' tendency to seek consistency versus variety in sequential choices. We propose that activation of concepts related to a positive frame of repetition (e.g., “loyalty”) triggers a preference‐based construal of consumption that encourages consistency seeking. In contrast, activation of concepts related to a negative frame of repetition (e.g., “boredom”) triggers a satiation‐based construal of consumption that encourages variety seeking. Four studies demonstrate that which construal of consumption consumers adopt can be activated outside of awareness, impacts consumers' experienced satiation, and determines in turn the amount of variety they incorporate into their choices.
Therapeutic options in patients with early T stage and advanced N stage of tonsillar squamous cell carcinomas
Authors: Chung Man Ki , Son Young‐Ik , Cho Jae Keun , So Yoon Kyoung , Woo Seung Hoon , Jeong Han‐Sin , Baek Chung‐Hwan 
Published: October 2010

OBJECTIVETo compare the therapeutic role of surgery followed by radiotherapy (OPRT) and concurrent chemoradiotherapy (CCRT) in patients with early T (T1/T2) and advanced N (N2/N3) stage tonsillar squamous cell carcinoma.STUDY DESIGNHistorical cohort study.SETTINGA tertiary hospital.SUBJECTS AND METHODSThe medical records of 42 patients who met the eligible criteria (24 patients were treated by OPRT, 18 patients by CCRT) were reviewed.RESULTSMean overall survival (OS) and disease‐free survival (DFS) were 49.0 months and 43.0 months in OPRT group, respectively, and 39.6 months and 35.0 months in CCRT group, respectively (P = 0.18 for OS, P = 0.29 fr DFS between the two groups). There was also no significant difference in survival estimates between OPRT and CCRT group in terms of two‐year OS (P = 0.18) and two‐year DFS (P = 0.45). In the European Organization for Research and Treatment of Cancer (EORTC) QLQ‐C30, the scores for global health status and symptom scales did not differ between the two groups. However, the OPRT group reported better functional scales and significantly higher scores for cognitive (P = 0.008) and social function (P = 0.03). Among single items, a significantly lower score for insomnia (P = 0.007) was noted in the OPRT group. In EORTC QLQ‐H&N35 modules, there were no significantly different scales between the two groups except scores for nutritional supplements, in which the OPRT group presented lower symptom scores (P = 0.02).CONCLUSIONOPRT could be still a viable option for managing selected cases of advanced oropharyngeal cancer because one can expect comparable therapeutic outcome as well as quality of life.
Servandoni at Württemberg
Authors: States Bert O. 
Published: October 2010

On June 15, 1763, Jean Nicholas Servandoni was hired for one year at a salary of 15,000 marks (7,500 gulden), travel expenses, free lodging, and a carriage to work at the court of Herzog Karl Eugen in Württemberg. Thanks to the industry of Joseph Uriot, the Duke's librarian, we have brief but invaluable descriptions of the fifteen decorations which he produced for the spectacles of February 11, 1764, the magnificent festival in honor of the Duke's birthday.Not at the opera, nor at any time in his career, was Servandoni's genius challenged as it was here, for he was in the company of Europe's most celebrated theatre personalities and perhaps its most sophisticated audience. His colleague for the occasion was Innocenz Colomba (1717–1793), an Italian designer of wide reputation, who had worked for the Duke since 1761. The operas were in the charge of Niccolo Jommelli, the chapel master there, and the ballets of Jean-Georges Noverre and his company of one hundred dancers, not including twenty principal performers each of whom had been first, dancer at one of Italy's chief theatres. The costumes were designed by Louis Boquet who spent a month each year at Württemberg.
Theatre Audiences of Japan
Authors: Lovell John 
Published: October 2010

In Japan it is easier to realize than in America a basic but neglected truth, namely, that the audience, and not the people on the stage, is the heart of the theatre. In America plays are, and have been generally, written to attract audiences, but not definite audiences: actually audiences in hodgepodge, whatever multitude can be induced to attend. In Japan, traditionally, the drama has been created for definite audiences.The Noh drama was originally produced for an audience of nobility and high dignity, both from the religious and from the civil standpoints. Originally Noh plays were acted exclusively in shrines to propitiate the deities of Shinto. On the other hand, they were enthusiastically supported by theshōguns(the Japanese military dictators who, though paying nominal court to the emperors, were the real rulers in Japan for several hundred years) and somewhat regulated by the tastes and preferences of thedaimyōs(the hereditary feudal nobles).
Wild Apaches in the Effete East: A Theatrical Adventure of John P. Clum
Authors: Ryan Pat M. 
Published: October 2010

No one at the Indian Bureau, in Washington, seemed interested when, early in the summer of 1876, Indian Agent John P. Clum suggested taking a carload of his San Carlos Apaches back East –“to see the greatness of our United States and become impressed by the progress of their white brothers.” So Clum relates in the semi-autobiographical book Apache Agent.Two years before, in Feburary, 1874, he had been commissioned :by President Grant as Agent for the Apaches at the San Carlos Indian Reservation, Arizona Territory.
Fragmented Autobiography
Authors: Morley Malcolm 
Published: October 2010

Malcolm Morley was born at Aldershot, England, on 20 May 1890. Intensely interested in the theatre from an early age, he took part in amateur and semi-professional productions. Due to some parental opposition to a theatrical career, he left England in 1912, to make his way as an actor on the American Stage. His early efforts are described in the following pages.Returning to England in 1920, he led an active theatrical life as actor, producer and manager. He was associated with the management of the Everyman Theatre, Hampstead, during its most influential years, when its successes included the first English productions of Strindberg's The Father and Ostrovsky's The Storm.
Meager Lead and Joyous Consequences: RSC Triumphs Among Shakespeare's Minor Plays
Authors: Shaw William P. 
Published: October 2010

Bassanio's words, as he chooses the correct casket to win Portia as his wife, might offer an insight to the production history of the Royal Shakespeare Company:An impressive number of the RSC's greatest theatrical triumphs have been stagings of Shakespeare's “meager lead,” his lesser or minor plays. To seek the common element in these surprising coups, I will examine four productions of such plays, one from each of the conventional generic categores, and spanning four decades in the history of the RSC: Brook's Love's Labor's Lost (1946) and Titus Andronicus (1955), Hall's and Barton's Troilus and Cressida (1960), Hands' Henry VI, Parts I, II, and III (1977).
Where was the Altar?
Authors: Ashby Clifford 
Published: October 2010

After centuries of study, an untold number of scholars have agreed that the City Dionysia of fifth-century Athens involved an animal sacrifice to the god Dionysos, and that this event took place in the theatre before the beginning of the play competition. The usual assumption has been that this sacrifice was offered upon an altar situated at the exact center of a circular orchestra.This placement fits well with the theory that tragedy grew from a dithyrambic chorus dancing in a circle around the altar of Dionysos. But now that the dogma of the originally circular orchestra has been questioned, some attention must also be given to the location of the altar, a supposedly standard piece of theatre furniture. The following pages will (1) discuss the origin of the concept of a centrally located altar; (2) examine the literary, artistic, and architectural evidence which relate to altar placement; and (3) suggest a possible alternative to the central location.
Which Fiddler Calls the Tune? ThePlayboyRiots and the Politics of Nationalist Theatre Spectatorship
Authors: Trotter Mary 
Published: October 2010

In October of 1903,The United Irishman, a leading newspaper of the Irish nationalist movement, published an essay by William Butler Yeats entitled “The Irish National Theatre and Three Sorts of Ignorance.” Yeats wrote this essay after an infuriated nationalist community protested the Irish National Theatre Society's production of John Millington Synge's play,In the Shadow of the Glen. In response to Yeats's admonishment of the nationalist movement for putting politics over aesthetics in their creation and judgment of Irish drama, Arthur Griffith, the editor of the newspaper, added some remarks of his own:Mr. Yeats does not give any reason why if the Irish National Theatre has no propaganda save that of good art it should continue to call itself either Irish or National. If the Theatre be solely an Art Theatre, then its plays can be fairly criticized from the standpoint of art. But whilst it calls itself Irish National its productions must be considered and criticised as Irish National productions.
Non-respiratory infections – specific considerations in care homes
Authors: Ewan Victoria , Gordon Adam 
Published: October 2010

SummaryThis review provides an update on current evidence surrounding the epidemiology, treatment and prevention of non-respiratory infections in care homes. It covers urinary tract infection (UTI), methicillin-resistantStaphylococcus aureus(MRSA), decubitus ulcers, scabies, tinea infections and viral and bacterial gastroenteritis. The care home sector provides a unique ecological niche for infections, housing frail older people with multiple co-morbidities and frequent contact with healthcare services in a semi-closed environment. This leads to differences in the diagnosis and management of infections – particularly of outbreaks – when compared with community-dwelling counterparts. It is essential that care home staff play a role in the early recognition, isolation and treatment of infections, but they are often not trained as healthcare professionals – this presents a challenge to systematized response. Effective interface between care homes, public health and infection control services are essential to the delivery of care, yet it is not clear how to structure such links most effectively.
Dr Führer's Wanderjahre: The Early Career of a Victorian Archaeologist
Authors: HUXLEY ANDREW 
Published: October 2010

AbstractThe Rev. Dr A.A. Führer lived to the age of seventy-seven. Herein is examined his first forty years. Trained as an Oriental Linguist, Führer eventually found employment as a field archaeologist. Three years after his appointment, the Archaeological Survey of India entered the worst crisis of its existence. Führer reacted in ways incompatible with scholarly integrity. It remains to be seen whether he committed further transgressions and or forgeries during his final thirty-seven years.
The Syntax ofhou後 in Temporal Phrases in Han Period Chinese
Authors: MEISTERERNST BARBARA 
Published: October 2010

AbstractIn this paper a unified account of the syntax of temporal phrases with the locative morphemehou後 followed by a NPtemp, a measure NP, is presented. Identical to bare noun phrase temporal adverbials,hou-phrases predominantly occur in sentence-initial/topic position and establish the temporal frame for the situation the predicate refers to; by default they refer to a point of time. According to the analysis presented,houexplicitly serves to relate one situation to a previous situation in the narrative; the NPtempmeasures the interval, the period of time, elapsed since the previous situation took place, and accordingly the NPtempis analysed as an appositional measure phrase. This analysis of the NPtempyields an analysis ofhou後 as an adverbially employed noun which syntactically retains its nominal characteristics and thus permits the addition of an apposition. Additionally, the nominal analysis ofhouis the only one which accounts for all syntactic variants of thehou-phrase in Han period Chinese.
ANALYSIS OF THE INEXACT UZAWA ALGORITHMS FOR NONLINEAR SADDLE-POINT PROBLEMS
Authors: LI JIAN-LEI , HUANG TING-ZHU , LI LIANG 
Published: October 2010

AbstractInexact Uzawa algorithms for solving nonlinear saddle-point problems are proposed. A simple sufficient condition for the convergence of the inexact Uzawa algorithms is obtained. Numerical experiments show that the inexact Uzawa algorithms are convergent.
MEASURING THE HUBBLE CONSTANT WITH THE HUBBLE SPACE TELESCOPE
Authors: Freedman W. L. , Kennicutt R. C. , Mould J. R. 
Published: October 2010

AbstractTen years ago our team completed the Hubble Space Telescope Key Project on the extragalactic distance scale. Cepheids were detected in some 25 galaxies and used to calibrate four secondary distance indicators that reach out into the expansion field beyond the noise of galaxy peculiar velocities. The result was H0 = 72 ± 8 km s−1 Mpc−1 and put an end to galaxy distances uncertain by a factor of two. This work has been awarded the Gruber Prize in Cosmology for 2009.
Water on Planets
Authors: Bell James F 
Published: October 2010

AbstractWater is an abundant molecule in the Cosmos. It has exploitable and unique spectroscopic and physical properties and has been found to be ubiquitous in places that we would expect in the standard model of solar system formation and nebular condensation: beyond the snow line in outer solar system planets, moons, asteroids, and comets. However, water is also an important constituent of planetary bodies (dominating at least one of their surfaces) in the inner solar system, likely indicating significant mixing between inner and outer solar system reservoirs of water during planetary accretion and the early history of the solar system. Water has played a critical role in the differential evolution of the terrestrial planets Venus, Earth, and Mars, and the concept of the “habitable zone” where liquid water could be stable on an Earth-like planet provides a starting point for assessing the habitability of worlds in our solar system and beyond. Examples of potentially habitable environments outside this zone in our own solar system warn us that this concept should only be a guide, however-important exceptions will no doubt occur. Recent discoveries of past liquid water and abundant present subsurface ice on Mars, of water reservoirs in unexpected places like the poles of Mercury and the Moon and the subsurface of Enceladus, of water in circumstellar disks and in the atmospheres of extrasolar planets, and the expectation of the discovery of water on Earth-like worlds in the habitable zones around other stars make this an exciting time in the study of water on planets both in our own solar system, and beyond.
Do Low Luminosity Stars Matter?
Authors: Ruiz María Teresa 
Published: October 2010

AbstractHistorically, low luminosity stars have attracted very little attention, in part because they are difficult to see except with large telescopes, however, by neglecting to study them we are leaving out the vast majority of stars in the Universe. Low mass stars evolve very slowly, it takes them trillions of years to burn their hydrogen, after which, they just turn into a He white dwarf, without ever going through the red giant phase. This lack of observable evolution partly explains the lack of interest in them. The search for the “missing mass” in the galactic plane turned things around and during the 60s and 70s the search for large M/L objects placed M-dwarfs and cool WDs among objects of astrophysical interest. New fields of astronomical research, like BDs and exoplanets appeared as spin-offs from efforts to find the “missing mass”. The search for halo white dwarfs, believed to be responsible for the observed microlensing events, is pursued by several groups. The progress in these last few years has been tremendous, here I present highlights some of the great successes in the field and point to some of the still unsolved issues.
Galaxy formation from dry and hydro simulations
Authors: Ciotti Luca 
Published: October 2010

AbstractThe effects of dry and wet merging on the Scaling Laws (SLs) of elliptical galaxies (Es) are discussed. It is found that the SLs, possibly established at high redshift by the fast collapse of gas-rich and clumpy stellar distributions in preexisting dark matter halos following the cosmological SLs, are compatible with a (small) number of galaxy mergers at lower redshift.
The growth of the red-sequence in clusters since ≃1
Authors: Muñoz Roberto P. , Barrientos L. F. , Koester B. P. , Gilbank D. G. , Gladders M. D. , Yee H. K. C. 
Published: October 2010

AbstractWe use deep nIR imaging of 15 galaxy clusters at z ≃ 1 to study the build-up of the red-sequence in rich clusters since the Universe was half its present age. We measured, for the first time, the luminous-to-faint ratio of red-sequence galaxies at z=1 from a large ensemble of clusters, and found an increase of 100% in the ratio of luminous-to-faint red-sequence galaxies from z=0.45 to 1.0. The measured change in this ratio as function of redshift is well-reproduced by a simple evolutionary model developed in this work, that consists in an early truncation of the star formation for bright cluster galaxies and a delayed truncation for faint cluster galaxies.
JD2 - Diffuse Light in Galaxy Clusters
Authors: Arnaboldi Magda , Gerhard Ortwin 
Published: October 2010

AbstractDiffuse intracluster light (ICL) has now been observed in nearby and in intermediate redshift clusters. Individual intracluster stars have been detected in the Virgo and Coma clusters and the first color-magnitude diagram and velocity measurements have been obtained. Recent studies show that the ICL contains of the order of 10% and perhaps up to 30% of the stellar mass in the cluster, but in the cores of some dense and rich clusters like Coma, the local ICL fraction can be high as 40%-50%. What can we learn from the ICL about the formation of galaxy clusters and the evolution of cluster galaxies? How and when did the ICL form? What is the connection to the central brightest cluster galaxy? Cosmological N-body and hydrodynamical simulations are beginning to make predictions for the kinematics and origin of the ICL. The ICL traces the evolution of baryonic substructures in dense environments and can thus be used to constrain some aspects of cosmological simulations that are most uncertain, such as the modeling of star formation and the mass distribution of the baryonic component in galaxies.
Probing fundamental physics with pulsars
Authors: Lorimer Duncan R. , McLaughlin Maura A. 
Published: October 2010

AbstractPulsars provide a wealth of information about General Relativity, the equation of state of superdense matter, relativistic particle acceleration in high magnetic fields, the Galaxy's interstellar medium and magnetic field, stellar and binary evolution, celestial mechanics, planetary physics and even cosmology. The wide variety of physical applications currently being investigated through studies of radio pulsars rely on: (i) finding interesting objects to study via large-scale and targeted surveys; (ii) high-precision timing measurements which exploit their remarkable clock-like stability. We review current surveys and the principles of pulsar timing and highlight progress made in the rotating radio transients, intermittent pulsars, tests of relativity, understanding pulsar evolution, measuring neutron star masses and the pulsar timing array