bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristic intraseasonal oscillation of rainfall and its effect on interannual variability over Bangladesh during boreal summer
Authors: Fujinami Hatsuki , Hatsuzuka Daisuke , Yasunari Tetsuzo , Hayashi Taiichi , Terao Toru , Murata Fumie , Kiguchi Masashi , Yamane Yusuke , Matsumoto Jun , Islam Md. Nazrul , Habib Arjumand 
Published: April 2010

AbstractIntraseasonal oscillation (ISO) of rainfall during the summer monsoon season (June–August) and its plausible effect on interannual variation (IAV) of total summer monsoon rainfall over Bangladesh are examined using daily rainfall data from 25 rain‐gauge stations for 20 years (1981–2000). Submonthly scale (7–25 days) ISO is a dominant mode of summer rainfall fluctuation over Bangladesh. In the active (suppressed) ISO phases, a cyclonic (anticyclonic) circulation anomaly develops at the low‐level troposphere from northeastern India to Bangladesh, and an anticyclonic (cyclonic) circulation anomaly appears over the Bay of Bengal, accompanied by the enhancement of westerly/southwesterly (easterly/southeasterly) moisture flux anomalies over Bangladesh. The IAV of total summer monsoon rainfall is significantly correlated with that of the rainfall variance, mainly in the submonthly scale, suggesting that the ISO activity controls the IAV of the total summer monsoon rainfall. Moreover, the spatial patterns of atmospheric circulation and convection associated with the ISO and the IAV are quite similar to each other around the monsoon trough, especially from northeastern India to Bangladesh. In wet monsoon years, more frequent strong submonthly scale ISOs and a larger number of rainy days related to the active ISO phase are evident compared with that of dry monsoon years. Climatologically, Bangladesh is one of the most predominant areas of submonthly scale ISO; however, 30–60‐day ISO is not prominent. These characteristic features probably allow the submonthly scale ISO to modulate the total seasonal rainfall and the spatial patterns of circulation and convection over and near Bangladesh. Copyright © 2010 Royal Meteorological Society
Responses of Batis maritima plants challenged with up to two‐fold seawater NaCl salinity
Authors: Debez Ahmed , Saadaoui Dhouha , Slama Inès , Huchzermeyer Bernhard , Abdelly Chedly 
Published: April 2010

AbstractBatis maritima is a promising halophyte for sand‐dune stabilization and saline‐soil reclamation. This species has also applications in herbal medicine and as an oilseed crop. Here, we address the plant response to salinity reaching up to two‐fold seawater concentration (0–1000 mM NaCl), with a particular emphasis on growth, water status, mineral nutrition, proline content, and photosystem II integrity. Plant biomass production was maximal at 200 mM NaCl, and the plants survived even when challenged with 1000 mM NaCl. Plant water status was not impaired by the high accumulation of sodium in shoots, suggesting that Na+ compartmentalization efficiently took place in vacuoles. Concentrations of Mg2+ and K+ in shoots were markedly lower in salt‐treated plants, while that of Ca2+ was less affected. Soluble‐sugar and chlorophyll concentrations were hardly affected by salinity, whereas proline concentration increased significantly in shoots of salt‐treated plants. Maximum quantum efficiency (Fv/Fm), quantum yield of PSII (ΦPSII), and electron‐transport rate (ETR) were maximal at 200–300 mM NaCl. Both nonphotochemical quenching (NPQ) and photochemical quenching (qP) were salt‐independent. Interestingly, transferring the plants previously challenged with supraoptimal salinities (400–1000 mM NaCl) to the optimal salinity (200 mM NaCl) substantially restored their growth activity. Altogether, our results indicate that B. maritima is an obligate halophyte, requiring high salt concentrations for optimal growth, and surviving long‐term extreme salinity. Such a performance could be ascribed to the plant capability to use sodium for osmotic adjustment, selective absorption of K+ over Na+ in concomitance with the stability of PSII functioning, and the absence of photosynthetic pigment degradation.
Nitrogen effects on total flavonoids, chlorogenic acid, and antioxidant activity of the medicinal plant Chrysanthemum morifolium
Authors: Liu Dahui , Liu Wei , Zhu Duanwei , Geng Mingjian , Zhou Wenbing , Yang Tewu 
Published: April 2010

AbstractChrysanthemum morifolium (Ramat.) has a long history of cultivation and use as a traditional medicine and tea plant in China. A greenhouse experiment with potted soil–quarz mixture studied the effects of nitrogen supply (0, 56, 112, 167, 224, 334, 501, 556, and 668 mg N kg–1) on concentrations and ratios of total flavonoids and chlorogenic acid in the flowers of C. morifolium using spectrophotometric and HPLC methods. The antioxidant activity of the flowers was determined as the radical scavenging activities of hydroxyl, superoxide anion, and 2,2‐diphenyl‐1‐picrylhydrazyl hydrate (DPPH) free radicals. A high N supply decreased the concentrations of total flavonoids by 18%–35% and that of chlorogenic acid by 8%–60% compared to a low N‐supply rate. At the same time, increasing N supply significantly decreased the antioxidant activity of the flowers. The antioxidant activity of C. morifolium flowers was significantly positively correlated with the concentrations of total flavonoids and chlorogenic acid. We conclude that an N supply in excess of 300 mg (kg soil)–1 will negatively affect the antioxidant activity and thereby reduce the quality of C. morifolium flowers.
Structural and vibrational analyses of 2‐(2‐benzofuranyl)‐2‐imidazoline
Authors: Contreras C. D. , Montejo M. , López González J. J. , Zinczuk J. , Brandán S. A. 
Published: April 2010

AbstractWe have studied 2‐(2‐benzofuranyl)‐2‐imidazoline (BFI) and characterized it by using infrared and Raman spectroscopies. The density functional theory (DFT) method together with Pople's basis set shows that two conformers exist for the title molecule as have been theoretically determined in the gas phase and that, probably, an average of both conformations is present in the solid phase. The harmonic vibrational wavenumbers for the optimized geometry of the latter conformer were calculated at the B3LYP/6‐31G* level in the proximity of the isolated molecule. For a complete assignment of the IR and Raman spectra in the compound in the solid phase, DFT calculations were combined with Pulay's scaled quantum mechanics force field (SQMFF) methodology in order to fit the theoretical wavenumbers to the experimental ones. Copyright © 2010 John Wiley & Sons, Ltd.
Association between TP53 gene ARG72PRO polymorphism and chromosome aberrations in human cancers
Authors: Litviakov Nicolay V. , Denisov Evgeny V. , Takhauov Ravil' M. , Karpov Andrey B. , Skobel'skaja Elena V. , Vasil'eva Elena O. , Goncharik Olesya O. , Ageeva Alena M. , Mamonova Natalya V. , Mezheritskiy Stanislav A. , Sevost'janova Natalya V. , Koshel Andrey P. 
Published: April 2010

AbstractIt is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the well‐known Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actually, polymorphic variants Arg and Pro were found to have different properties of regulation of TP53‐dependent DNA repair target genes, that can effect various levels of chromosome aberrations in cancer patients with these genotypes. Here, we studied frequency of chromatid breaks (CB), chromosome‐type aberrations (CTA) and aberrant cells (AC) in cancer patients (n = 102) with various Arg72Pro genotypes. It was shown that the Arg variant of TP53 gene is associated with high frequency of AC and chromatid breaks. That is Arg/Arg carriers have more different chromosome aberrations in comparison to individuals with Arg/Pro and Pro/Pro genotypes (P < 0.05). Conversely, the lowest level of AC and chromatid breaks were detected in cancer patients with the Pro/Pro genotype. A completely unexpected result was that women with Arg/Arg genotype had the most high frequency of CB and AC in comparison to Arg/Pro and Pro/Pro women carriers (P < 0.001). In the group of male patients we did not show any differences in chromosome aberrations between carriers of Arg72Pro genotypes. In conclusion, the TP53 gene Arg72Pro polymorphism appreciably influence on occurrence of chromosome aberrations in cancer. Mol. Carcinog. © 2010 Wiley‐Liss, Inc.
Characteristics of locomotion, muscle strength, and muscle tissue in regenerating rat skeletal muscles
Authors: Iwata Akira , Fuchioka Satoshi , Hiraoka Koichi , Masuhara Mitsuhiko , Kami Katsuya 
Published: April 2010

AbstractAlthough numerous studies have aimed to elucidate the mechanisms used to repair the structure and function of injured skeletal muscles, it remains unclear how and when movement recovers following damage. We performed a temporal analysis to characterize the changes in movement, muscle function, and muscle structure after muscle injury induced by the drop‐mass technique. At each time‐point, movement recovery was determined by ankle kinematic analysis of locomotion, and functional recovery was represented by isometric force. As a histological analysis, the cross‐sectional area of myotubes was measured to examine structural regeneration. The dorsiflexion angle of the ankle, as assessed by kinematic analysis of locomotion, increased after injury and then returned to control levels by day 14 post‐injury. The isometric force returned to normal levels by day 21 post‐injury. However, the size of the myotubes did not reach normal levels, even at day 21 post‐injury. These results indicate that recovery of locomotion occurs prior to recovery of isometric force and that functional recovery occurs earlier than structural regeneration. Thus, it is suggested that recovery of the movement and function of injured skeletal muscles might be insufficient as markers for estimating the degree of neuromuscular system reconstitution. Muscle Nerve 41: 694–701, 2010
Effect of physical training on pain sensitivity and trapezius muscle morphology
Authors: Nielsen Pernille Kofoed , Andersen Lars L. , Olsen Henrik B. , Rosendal Lars , Sjøgaard Gisela , Søgaard Karen 
Published: April 2010

AbstractThe objective of this study was to investigate morphological and physiological characteristics of painful muscles in women with (MYA,n= 42) and without (CON,n= 20) trapezius myalgia, and assess changes in response to a 10‐week, randomized, controlled trial. MYA accomplished: (1) specific strength training (SST); (2) general fitness training (GFT); or (3) reference intervention (REF). Differences in muscle morphology could not be detected by ultrasound imaging. Significantly lower pressure pain threshold (PPT) and shoulder torque were observed for MYA, indicating pain‐related lack of full activation. After 10 weeks, increased shoulder torque and PPT of the painful trapezius were observed in SST solely. The PPT of a pain‐free reference muscle was increased in response to both SST and GFT, indicating a general effect of physical activity on pain perception. This study shows clinically relevant improvement in pain sensitivity and muscle strength capacity in response to SST. Muscle Nerve, 2010
Chronic inflammatory demyelinating polyneuropathy associated with tumor necrosis factor‐α antagonists
Authors: Alshekhlee Amer , Basiri Kevian , Miles J. Douglas , Ahmad Saef A. , Katirji Bashar 
Published: April 2010

AbstractBiologic therapy with tumor necrosis factor (TNF)‐α antagonists for rheumatoid arthritis has been well established. We describe two patients with rheumatoid arthritis who developed chronic inflammatory demyelinating polyneuropathy (CIDP) during their course of therapy with TNF‐α antagonists. A 45‐year‐old woman and a 49‐year‐old man, both with a history of rheumatoid arthritis, were treated with etanercept and infliximab, respectively. Clinical signs of peripheral neuropathy developed 2 weeks and 12 months after the initiation of TNF‐α antagonists. Electrodiagnostic studies at variable points during the disease course showed signs of acquired demyelination consistent with CIDP. Cerebrospinal fluid examination showed albuminocytologic dissociation (total protein concentration 118 mg/dl and 152 mg/dl, respectively). Both patients failed to improve after discontinuation of the offending agent, and they responded poorly to corticosteroids. However, there was clinical and electrophysiologic recovery after initiation of intravenous immunoglobulin (IVIg) therapy. CIDP may occur early or late during the treatment course with TNF‐α antagonists. IVIg may reverse and stabilize the inflammatory process. Muscle Nerve 41: 742–747, 2010
Trigeminal neuropathy from perineural spread of an amyloidoma detected by blink reflex and thin‐slice magnetic resonance imaging
Authors: Yamazaki Yuu , Ochi Kazuhide , Nakata Yuki , Dohi Eisuke , Eguchi Kuniki , Yamaguchi Satoshi , Matsushige Toshinori , Ueda Takeshi , Amatya Vishwa J. , Takeshima Yukio , Nakamura Takeshi , Ohtsuki Toshiho , Kohriyama Tatsuo , Matsumoto Masayasu 
Published: April 2010

AbstractThe purpose of this study was to describe a trigeminal neuropathy caused by the perineural spread of an amyloidoma. A 62‐year‐old woman had an amyloidoma of the Gasserian ganglion that was hypointense on T2‐weighted images; the lesion was enhanced by gadolinium on thin‐slice magnetic resonance imaging. There was no evidence of systemic amyloidosis or underlying inflammatory or neoplastic disorders. Her blink reflex and thin‐slice magnetic resonance imaging demonstrated that the right trigeminal nerve was involved. A rare trigeminal neuropathy resulted from the perineural spread of a primary amyloidoma that was difficult to detect by conventional magnetic resonance imaging. Muscle Nerve, 2010
Novel diagnostic features of dysferlinopathies
Authors: Rosales Xiomara Q. , Gastier‐Foster Julie M. , Lewis Sarah , Vinod Malik , Thrush Devon L. , Astbury Caroline , Pyatt Robert , Reshmi Shalini , Sahenk Zarife , Mendell Jerry R. 
Published: April 2010

AbstractReports of dysferlinopathy have suggested a clinically heterogeneous group of patients. We identified specific novel molecular and phenotypic features that help distinguish dysferlinopathies from other forms of limb‐girdle muscular dystrophy (LGMD). A detailed history, physical exam, and protein and mutation analysis of genomic DNA was done for all subjects. Five of 21 confirmed DYSF gene mutations were not previously reported. A distinct “bulge” of the deltoid muscle in combination with other findings was a striking feature in all patients. Six subjects had atypical calf enlargement, and 3 of these exhibited a paradoxical pattern of dysferlin expression: severely reduced by direct immunofluorescence with overexpression on Western blots. Six patients showed amyloid deposits in muscle that extended these findings to new domains of the dysferlin gene, including the C2G domain. Correlative studies showed colocalization of amyloid with deposition of dysferlin. The present data further serve to guide clinicians facing the expensive task of molecular characterization of patients with an LGMD phenotype. Muscle Nerve 42: 14–21, 2010
Vascular pathology in dermatomyositis and anatomic relations to myopathology
Authors: Pestronk Alan , Schmidt Robert E. , Choksi Rati 
Published: April 2010

AbstractThe causes of perifascicular myofiber atrophy and capillary pathology in dermatomyositis are incompletely understood. We studied 11 dermatomyositis muscles by histochemistry, immunohistochemistry, and ultrastructure. We found that endomysial capillaries within regions of perifascicular atrophy are not entirely lost, but they have reduced size, endothelial loss, C5b9 complement deposits, and relatively preserved connective tissue molecules and pericytes. In all muscles, the perimysium varies regionally. Some areas contain intermediate‐sized vessels. Others are avascular. In dermatomyositis, vascular perimysium contains abnormal vessel fragments, perivascular inflammation, and increased PECAM‐1. Perifascicular myofiber atrophy and capillary pathology are concentrated near the avascular perimysium. We conclude that both perimysial intermediate‐sized vessels and endomysial capillaries within regions of perifascicular myofiber atrophy are abnormal in dermatomyositis. Capillary damage and myofiber atrophy are concentrated in regions distant from intermediate‐sized perimysial vessels. Chronic immune vascular damage and insufficiency in dermatomyositis may cause ischemia, myofiber atrophy, and capillary damage in “watershed” regions of muscle near the avascular perimysium. Muscle Nerve, 2010
Immunopathogenesis of juvenile dermatomyositis
Authors: Khanna Sahil , Reed Ann M. 
Published: April 2010

AbstractThere is increasing evidence for involvement of the mechanisms of the innate immune system in the pathogenesis of idiopathic inflammatory myopathies (IIMs), especially in the adult and juvenile forms of dermatomyositis. Juvenile dermatomyositis (JDM) is the most common form of childhood IIM, and this review focuses on recent advances in understanding the actions of the innate immune system in this condition. Over the last few years, great strides have been made in understanding immune dysregulation in IIM, including JDM. Novel autoantibodies have been identified, and new genetic contributions have been described. Among the most striking findings is type I interferon activity in JDM tissue and peripheral blood. This is in conjunction with the description of dysregulation of the major histocompatibility complex (MHC) class I gene and identification of plasmacytoid dendritic infiltrates as the possible cellular source of type I interferons. These findings also point toward the potential prognostic value of muscle biopsies and have helped expand our understanding of the etiopathogenesis of IIM. Muscle Nerve 41: 581–592, 2010
Efficacy and adverse events of sacral nerve stimulation for overactive bladder: A systematic review
Authors: Siddiqui Nazema Y. , Wu Jennifer M. , Amundsen Cindy L. 
Published: April 2010

AbstractAimsTo systematically review the literature regarding efficacy and adverse events of sacral nerve stimulation (SNS) via the InterStim device for treatment of women with refractory overactive bladder (OAB).MethodsWe searched MEDLINE, Embase, Web of Science, and the Cochrane Collaboration databases from 1980 to September 2008. All English studies reporting on efficacy or adverse events of SNS for the treatment of refractory OAB were considered. Only studies where 30 or more women received the complete therapy (implanted lead and generator) were included. The quality of the studies (good, fair, or poor) was assessed based on predefined criteria.ResultsSeven studies were designated “good” regarding efficacy of SNS for OAB. Multiple authors reported results from the same cohort of patients. In this instance, the highest quality study was chosen, leaving three independent studies regarding efficacy. In these studies, incontinent episodes per day and pad usage significantly improved after SNS therapy. Six studies were designated “good” regarding adverse events. Using tined leads, surgical revision rates ranged from 3% to 16%. Six percent of patients were explanted due to lack of efficacy and 5–11% of patients were explanted due to infection.ConclusionsBased on observational data, SNS appears effective for treatment of OAB in women. Adverse event rates with tined leads are lower than previously published estimates using non‐tined leads. High‐quality studies are needed to confirm our findings and to provide additional data regarding reprogramming, quality of life, and efficacy when compared to other therapies. Neurourol. Urodynam. 29:S18–S23, 2010. © 2010 Wiley‐Liss, Inc.
Afferent neurourology: A novel paradigm
Authors: Clemens J. Quentin 
Published: April 2010

AbstractThe term “afferent neurourology” is introduced to describe the study of sensory processing related to the genitourinary tract. Urologic disorders that are characterized by abnormal sensory processing are reviewed, and unique challenges to our understanding of these disorders are described. A paradigm which separates afferent urologic disorders from efferent disorders and structural abnormalities is presented. Neurourol. Urodynam. 29:S29–S31, 2010. © 2010 Wiley‐Liss, Inc.
Stem cell therapy for stress urinary incontinence
Authors: Nikolavsky Dmitriy , Chancellor Michael B. 
Published: April 2010

AbstractThe rhabdosphincter at the mid urethra is critical for maintaining urinary continence. In a setting of stress urinary incontinence stem cells transplanted into the site of the rhabdosphincter may augment sphincter regeneration and also release trophic factors promoting muscle and nerve integration of this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle‐derived stem cells (MDSCs). Neurourol. Urodynam. 29:S36–S41, 2010. © 2010 Wiley‐Liss, Inc.
Long‐term outcomes and patient satisfaction of continent catheterizable limb and augmentation cystoplasty simultaneous with salvage prostatectomy
Authors: Zafirakis Helen , De Elise J.B. , Pisters Louis L. , Pettaway Curtis , Westney O. Lenaine 
Published: April 2010

AbstractAimsWe evaluated the long‐term outcomes of augmentation cystoplasty and continent catheterizable limb formation in patients who underwent simultaneous salvage prostatectomy.MethodsTwelve men who underwent salvage prostatectomy with augmentation cystoplasty and either an appendicovesicostomy or Monti ileovesicostomy between October 2000 and February 2003 were assessed for long‐term surgical complications, reoperations, continence rates, and patient satisfaction using the Incontinence Symptom Index (ISI) questionnaire and a self‐designed catheterization questionnaire.ResultsIn addition to bladder augmentation, six patients underwent appendicovesicostomy, four had a Monti ileovesicostomy and two a spiral Monti ileovesicostomy. There were no intraoperative complications or surgical‐related deaths. Four patients required revision surgery (33%) at a mean of 39 months. Minor revisions were performed for stomal stenosis in two patients with stomal relocation in two patients. Ten of 12 patients were dry (83.3%) with a catheterization frequency of between 3 and 8 hr. At a mean follow‐up of 61 months (SD = 20.51), the mean ISI severity score was 1.86 (SD = 3.54) and the mean ISI bother score was 1 (SD 0.74). The majority (86%) would choose to undergo the surgery again.ConclusionsAlthough surgically challenging and associated with significant morbidity, salvage prostatectomy with concomitant bladder augmentation and continent catheterizable reconstruction is a feasible and effective means of obtaining adequate long‐term urinary continence, while preserving the native bladder. In comparison to similar historical patients with catheterizable limbs only, fewer of the augmented patients needed antimuscarinic medication and delayed augmentation was not necessary. Complications do not increase over time and the continence rates are stable. Neurourol. Urodynam. 29:S51–S56, 2010. © 2010 Wiley‐Liss, Inc.