bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cutting Edge: Natural Helper Cells Derive from Lymphoid Progenitors
Authors: Yang Qi , Saenz Steven A. , Zlotoff Daniel A. , Artis David , Bhandoola Avinash 
Published: October 2011

Abstract
Natural helper (NH) cells are recently discovered innate immune cells that confer protective type 2 immunity during helminth infection and mediate influenza-induced airway hypersensitivity. Little is known about the ontogeny of NH cells. We report in this study that NH cells derive from bone marrow lymphoid progenitors. Using RAG-1Cre/ROSA26YFP mice, we show that most NH cells are marked with a history of RAG-1 expression, implying lymphoid developmental origin. The development of NH cells depends on the cytokine receptor Flt3, which is required for the efficient generation of bone marrow lymphoid progenitors. Finally, we demonstrate that lymphoid progenitors, but not myeloid–erythroid progenitors, give rise to NH cells in vivo. This work therefore expands the lymphocyte family, currently comprising T, B, and NK cells, to include NH cells as another type of innate lymphocyte that derives from bone marrow lymphoid progenitors.
Teenage Acute Macular Neuroretinopathy
Authors: Rifkin Lana , Schaal Shlomit 
Published: October 2011

Purpose To present the first case of acute macular neuroretinopathy in a teenager. Methods Case report, optical coherence tomography, fluorescein angiography, electroretinography. Results Optical coherence tomography, fluorescein angiography, and electroretinography were used to diagnose acute macular neuroretinopathy. Laboratory results were positive for HLA-B7. Conclusions The rare diagnosis of acute macular neuroretinopathy should be considered in girls on oral contraceptives, with a recent history of acute viral illness, who present with acute rapid onset of multiple, paracentral scotomas.
Linguistic Predictors of Post‐Traumatic Stress Disorder Symptoms Following 11 September 2001
Authors: D'Andrea Wendy , Chiu Pearl H. , Casas Brooks R. , Deldin Patricia 
Published: October 2011

SummaryPrior research has linked content analysis drawn from text narratives to psychopathology in trauma survivors. This study used a longitudinal design to determine whether linguistic elements of narrative memories of first hearing about the events of 11 September 2001 predict later post‐traumatic stress disorder (PTSD). Narratives and self‐report PTSD symptoms were collected within 1 week and again 5 months after 9/11 in 40 undergraduates. People who used more “we” words at Time 1 had fewer acute PTSD symptoms. Use of more cognitive mechanism words, more religion words, more first‐person singular pronouns, and fewer anxiety words at Time 1 were related to more chronic PTSD symptoms. Linguistic characteristics accounted for variance in chronic PTSD symptoms above and beyond acute PTSD symptoms. This study provides evidence that lasting PTSD symptoms can be predicted through language in the immediate aftermath of the trauma. Copyright © 2011 John Wiley & Sons, Ltd.
Fabrication, microstructural analysis, and properties of poly(methyl methacrylate)/calcium carbonate particulates nanocomposites
Authors: Chang Z. C. , Lin C. B. , Chou Yi‐Chun , Lee Hung‐Chou 
Published: October 2011

AbstractThe poly(methyl methacrylate) (PMMA)/nanometer‐scaled calcium carbonate particulate nanocomposites prepared by means of the gas‐synthesis was investigated. PMMA absorbed the saturated solvent mixture (the ratio of calcium chloride dehydrate and methanol at 1.5, 4.5, and 6.0 g/100 g) at 40–60° and then desorbed the methanol completely and then CO2 gas diffused into the desorbed completely in specimens for 48 h at 60°, approximately 30‐nm calcium carbonate particulates were precipitated evenly to distribute in the PMMA matrix. The content of calcium carbonate particulates decreases with increasing concentration of the saturated solvent mixture. The transmittance of the nanocomposites decreases with the increasing content of calcium carbonate particulates and the cutoff wavelength of transmittance is shifted to the short wavelength side. Differential scanning calorimetry displayed the glass transition temperature of nanocomposites is much higher than the virgin PMMA. Compared with the original PMMA, with only 1.53 wt% calcium carbonate particulate loading, the PMMA‐matrix nanocomposites exhibit higher glass transition temperature. © 2011 Wiley Periodicals, Inc. Adv Polym Techn 31: 280–291, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/adv.20251
Synthesis and characterization of pH‐sensitive crosslinked (NIPA‐co‐AAC) nanohydrogels copolymer
Authors: Elsaeed Shimaa M. , Farag Reem K. , Maysour Nermien S. 
Published: October 2011

AbstractA thermoresponsive polymeric nanohydrogels has been synthesized by inverse microemulsion polymerization of N‐isopropylacrylamide (NIPA) and acrylic acid (AAc) using Aerosol (AOT) as a surfactant, ethylene glycol dimethacrylate (EGDMA) as a crosslinker, and 2,2′‐azobisisobutyronitrile (AIBN) as initiator. The effect of concentration of AIBN, EGDMA, and NIPA/AAc weight ratio was investigated. The lower critical solution temperature (LCST) of poly (NIPA‐co‐AAC) can be manipulated to be 40°C and 45°C which was correlated to amount of AAc that was copolymerized with NIPA. FTIR, 1H NMR, TEM, and DSC characterized the nanohydrogels. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
ChemInform Abstract: Magnetostructural Correlations in the Antiferromagnetic Co2‐xCux(OH)AsO4 (x = 0 and 0.3) Phases.
Authors: de Pedro I. , Rojo J. M. , Pizarro J. L. , Rodriguez Fernandez J. , Arriortua M. I. , Rojo T. 
Published: October 2011

AbstractThe title compounds are hydrothermally synthesized from stoichiometric precursors (Co,Cu)3(AsO4)2 in 5% aq.
ChemInform Abstract: Insights into Photoluminescence Property and Photocatalytic Activity of Cubic and Rhombohedral ZnIn2S4.
Authors: Shen Shaohua , Guo Penghui , Zhao Liang , Du Yuanchang , Guo Liejin 
Published: October 2011

AbstractZnIn2S4 is synthesized by thermal sulfidation of a Zn—In mixed oxide precursor with dry H2S gas for 4 h at either 300 °C yielding cubic ZnIn2S4 or at 800 °C resulting in rhombohedral ZnIn2S4.
ChemInform Abstract: Unprecedented Zeolite‐Like Framework Topology Constructed from Cages with 3‐Rings in a Barium Oxonitridophosphate.
Authors: Sedlmaier Stefan J. , Doeblinger Markus , Oeckler Oliver , Weber Johannes , Schmedt auf der Guenne Joern , Schnick Wolfgang 
Published: October 2011

AbstractBa19P36O10.54N61.46 Cl12.54 is synthesized from a mixture of BaS, PO(NH2)3, PS(NH2)3, and NH4Cl (evacuated silica tube, 200 °C, 12 h and 750 °C, 48 h; <90% yield).
ChemInform Abstract: An Unprecedented Vanadoniobate Cluster with “trans‐Vanadium” Bicapped Keggin‐Type {VNb12O40(VO)2}.
Authors: Guo Guiling , Xu Yanqing , Cao Jie , Hu Changwen 
Published: October 2011

AbstractThe crystal structures of (IV) and (VI) are determined by single crystal XRD.
ChemInform Abstract: Crystal Growth, Structures, and Optical Properties of the Cubic Double Perovskites Ba2MgWO6 and Ba2ZnWO6.
Authors: Bugaris Daniel E. , Hodges Jason P. , Huq Ashfia , zur Loye Hans‐Conrad 
Published: October 2011

AbstractSingle crystals of the title compounds are prepared from MgO or ZnO, WO3, and BaCO3 using K2CO3 as a flux (950—1050 °C, 36 h).
ChemInform Abstract: Practical β‐Masked Formylation and Acetylation of Electron‐Deficient Olefins Utilizing Tetra(n‐butyl)ammonium Peroxydisulfate.
Authors: Jung Jae Chul , Kim Yong Hae , Lee Kieseung 
Published: October 2011

AbstractRegioselective addition of 1,3‐dioxolanes (I) and (VI) to electron‐deficient olefins provides products (III) and (V) as formylation equivalents and compounds (VII) and (VIII) as acetylation equivalents.
ChemInform Abstract: Primary Amine Catalyzed Electrophilic Amination of α,α‐Disubstituted Aldehydes.
Authors: Desmarchelier Alaric , Yalgin Hasret , Coeffard Vincent , Moreau Xavier , Greck Christine 
Published: October 2011

AbstractAn epi‐quinine derivative ACI is found to be an efficient catalyst for the synthesis of α‐hydrazino aldehydes.
ChemInform Abstract: Synthesis of N‐Alkylated Amino Acids Using Fluorous‐Tagged Hydroxylamines.
Authors: Nielsen Simon D. , Smith Garrick P. , Begtrup Mikael , Kristensen Jesper L. 
Published: October 2011

AbstractThe synthesis of N‐alkylated amino acids starts with alkylation and Boc‐deprotection of fluorous‐tagged hydroxylamine (I).
ChemInform Abstract: Microwave Assisted Suzuki Reaction in N‐Butylpyridinium Salts/Water Systems.
Authors: dos Santos Castro Kelly L. , de Lima Paulo G. , e Miranda Leandro S. M. , de Souza Rodrigo O. M. A. 
Published: October 2011

AbstractIt is demonstrated that an ionic liquid derived from 4‐picoline is an efficient medium.
ChemInform Abstract: Accelerated Heck Reaction Using ortho‐Palladated Complex in a Nonaqueous Ionic Liquid with Controlled Microwave Heating.
Authors: Hajipour Abdol R. , Rafiee Fatemeh 
Published: October 2011

AbstractThe reaction occurs under conventional heating and under microwave irradiation conditions as well giving products in comparable yields exclusively as the (E)‐isomers.
ChemInform Abstract: Fascinating Reactivity in Gold Catalysis: Synthesis of Oxetenes Through Rare 4‐exo‐dig Allene Cyclization and Infrequent β‐Hydride Elimination.
Authors: Alcaide Benito , Almendros Pedro , Martinez del Campo Teresa , Fernandez Israel 
Published: October 2011

AbstractThe substitution pattern of the allenol substrate determines the reaction outcome of the gold‐catalyzed cyclization to yield either dihydrofurans (II)/(VI) or oxetenes (IV)/(VII).
ChemInform Abstract: Synthesis of N‐Vinyl 2,2‐Bisphosphonoaziridines from 1,1‐Bisphosphono‐2‐aza‐1,3‐dienes.
Authors: Mortier Pieter P. J. , Van Waes Frederik E. A. , Masschelein Kurt G. R. , Heugebaert Thomas S. A. , Stevens Christian V. 
Published: October 2011

AbstractIt is demonstrated that treatment of azadienes of type (I) and (VI) with diazomethane provides aziridines as main products.
ChemInform Abstract: Isothiourea‐Catalyzed Asymmetric O‐ to C‐Carboxyl Transfer of Furanyl Carbonates.
Authors: Joannesse Caroline , Morrill Louis C. , Campbell Craig D. , Slawin Alexandra M. Z. , Smith Andrew D. 
Published: October 2011

AbstractThe method renders possible the synthesis of α‐regioisomeric butenolide subunits as the major products.
ChemInform Abstract: Pd‐Mediated New Synthesis of Pyrroles: Their Evaluation as Potential Inhibitors of Phosphodiesterase 4.
Authors: Pal Manojit , et al. et al. 
Published: October 2011

AbstractA multi‐component reaction followed by Suzuki, Heck or Sonogashira coupling in a single pot is developed for the synthesis of the title compounds (VI), (IX), (XI), (XIII), and (XV).
ChemInform Abstract: Asymmetric Formal [3 + 2] Cycloaddition Reaction of Isocyanoesters to 2‐Oxobutenoate Esters by a Multifunctional Chiral Silver Catalyst.
Authors: Song Jin , Guo Chang , Chen Peng‐Hao , Yu Jie , Luo Shi‐Wei , Gong Liu‐Zhu 
Published: October 2011

AbstractThe reaction proceeds providing products with excellent enantioselectivities.
ChemInform Abstract: Catalytic Enantioselective Henry Reactions of Isatins: Application in the Concise Synthesis of (S)‐(—)‐Spirobrassinin.
Authors: Liu Lu , Zhang Shilei , Xue Fei , Lou Guangshun , Zhang Haoyi , Ma Shichao , Duan Wenhu , Wang Wei 
Published: October 2011

AbstractA highly efficient, cupreine‐catalyzed, enantioselective Henry reaction of isatin derivatives with nitroalkanes results in formation of chiral hydroxyoxindoles.
ChemInform Abstract: Constrained Tetramic Acids, Homostreptopyrrolidine, and Their Analogues Based on Unusual Intramolecular Wittig Olefination with Phosphorus Ylides.
Authors: Duris Andrej , Daich Adam , Berkes Dusan 
Published: October 2011

AbstractTetramic acids (III), (V), and (VII) are synthesized from aminobutenolides and the phosphonium ylide formed from salt (II), by tandem amidation/intramolecular Wittig olefination.
ChemInform Abstract: Licofelone—Nitric Oxide Donors as Anticancer Agents.
Authors: Liu Wukun , Zhou Jinpei , Liu Yinglin , Liu Haoran , Bensdorf Kerstin , Guo Cancheng , Gust Ronald 
Published: October 2011

AbstractFive licofelone‐nitric oxide donor conjugates (I) are prepared by a parallel synthesis approach and evaluated for their in vitro cytotoxicity.
ChemInform Abstract: Alumina Supported Ammonium Dihydrogenphosphate (NH4H2PO4/Al2O3): Preparation, Characterization and Its Application as Catalyst in the Synthesis of 1,2,4,5‐Tetrasubstituted Imidazoles.
Authors: Emrani Anahita , Davoodnia Abolghasem , Tavakoli‐Hoseini Niloofar 
Published: October 2011

AbstractThe catalyst shows high activity in the synthesis of imidazoles (IV) (10 examples) via multi‐component reaction of benzil, aromatic aldehydes, primary amines and NH4OAc under solvent‐free conditions.
ChemInform Abstract: Nickel(II)‐Catalyzed Diastereoselective [3 + 2] Cycloaddition of N‐Tosyl‐aziridines and Aldehydes via Selective Carbon—Carbon Bond Cleavage.
Authors: Wu Xingxing , Li Lei , Zhang Junliang 
Published: October 2011

AbstractAn efficient, mild and scalable method for the title synthesis is developed.
ChemInform Abstract: Versatile Three‐Component Procedure for Combinatorial Synthesis of Biologically Relevant Scaffold Spiro[indole‐thiazolidinones] under Aqueous Conditions.
Authors: Dandia Anshu , Singh Ruby , Bhaskaran Sumit , Samant Shriniwas D. 
Published: October 2011

AbstractThe reaction is carried out under environmentally benign conditions.
ChemInform Abstract: Merrifield Resin Supported Phenanthroline—Cu(I): A Highly Efficient and Recyclable Catalyst for the Synthesis of 2‐Aminobenzothiazoles via the Reaction of 2‐Haloanilines with Isothiocyanates.
Authors: Yang Jin , Li Pinhua , Wang Lei 
Published: October 2011

AbstractThe reaction is applicable to a variety of o‐bromoanilines (I) and aromatic isothiocyanates (II)/(IV) generating aminobenzothiazole products in good yields under mild conditions.
ChemInform Abstract: Synthesis and Antibacterial Activity of Various Substituted Oxadiazole Derivatives.
Authors: Kaur Hemlata , Kumar Sunil , Verma R. S. , Garg Amit , Saxena K. K. , Lata Suman , Kumar Ashok 
Published: October 2011

AbstractThe compounds (III) and (IV) are screened for their antibacterial activity against both types of Gram‐positive and Gram‐negative bacteria.
ChemInform Abstract: Divergent Approach to the Polymaxenolide and Pinnaic Acid Cores.
Authors: Ferrari Frank D. , Ledgard Andrew J. , Marquez Rodolfo 
Published: October 2011

AbstractA two‐step one‐pot procedure is developed to prepare pyrans (III), where (IIIa) represents the spirocyclic part of polymaxenolide.
ChemInform Abstract: Indium(III) Chloride Catalyzed Mukaiyama—Michael Addition: Synthesis of 2,6‐anti‐Tetrahydropyrans.
Authors: Chua Sin‐Siu , Alni Anita , Chan Li‐Ting Jocelyn , Yamane Motoki , Loh Teck‐Peng 
Published: October 2011

AbstractThe reaction proceeds under solvent‐free conditions and affords the anti‐products exclusively.
ChemInform Abstract: Synthesis of Novel 1‐Aryl‐9H‐xanthen‐9‐ones.
Authors: Esteves Catia I. C. , Santos Clementina M. M. , Brito Cristela M. , Silva Artur M. S. , Cavaleiro Jose A. S. 
Published: October 2011

AbstractThe simple one‐pot process involves condensation of 2‐methylchromone with cinnamaldehydes followed by an electrocyclization/oxidation sequence.
ChemInform Abstract: Activated Anilide in Heterocyclic Synthesis: Synthesis of New Dihydropyridines (IV), Dihydropyridazines (VIII) and Thiourea Derivatives (X).
Authors: Hafiz Ibrahim S. A. , Ramiz Mahmoud M. M. , Sarhan Ahmed A. M. 
Published: October 2011

AbstractNew dihydropyridines, dihydropyridazines and thiourea derivatives are accomplished by the reaction of butanamide and pyridine derivatives as starting materials with selected electrophilic reagents.
ChemInform Abstract: Heterocycles via Intramolecular Platinum‐Catalyzed Propargylic Substitution.
Authors: Liang Qiren , De Brabander Jef K. 
Published: October 2011

AbstractIntramolecular propargylic substitution of nucleophile‐tethered propargylic acetates is used to construct morpholines, dioxanes and cyclic sulfamates.
ChemInform Abstract: Synthesis and Biological Activities of Novel s‐Triazine Bridged Dinucleoside Analogues.
Authors: Shen Fengjuan , Li Xiaoliu , Zhang Xiaoyuan , Qin Zhanbin , Yin Qingmei , Chen Hua , Zhang Jinchao 
Published: October 2011

AbstractA series of novel s‐triazine linked “triple headed” dinucleoside analogues is synthesized by stepwise substitution of unprotected nucleosides with cyanuric chloride.
ChemInform Abstract: Stereospecificity in the Au‐Catalyzed Cyclization of Monoallylic Diols. Synthesis of (+)‐Isoaltholactone.
Authors: Unsworth William P. , Stevens Kiri , Lamont Scott G. , Robertson Jeremy 
Published: October 2011

AbstractA concise synthesis of the title compound (V) is presented with the Au‐catalyzed cyclization as key step.
ChemInform Abstract: Substituted N‐Aryl‐6‐pyrimidinones: A New Class of Potent, Selective, and Orally Active p38 MAP Kinase Inhibitors.
Authors: Devadas Balekudru , et al. et al. 
Published: October 2011

AbstractA series of highly potent and selective p38 MAP kinase inhibitors is developed originating from a substituted N‐aryl‐6‐pyrimidinone scaffold.
ChemInform Abstract: Development of Bicyclo[3.3.0]octadiene‐ or Dicyclopentadiene‐Based Chiral Diene Ligands for Transition‐Metal‐Catalyzed Reactions
Authors: Feng Chen‐Guo , Xu Ming‐Hua , Lin Guo‐Qiang 
Published: October 2011

AbstractReview: ca. 100 refs.
Design and CFD studies of multiphase separators—a review
Authors: Laleh Ali Pourahmadi , Svrcek William Y. , Monnery Wayne D. 
Published: October 2011

AbstractThe multiphase separators are generally the first and largest process equipment in an oil production platform. This primary separation step is a key element in the oil and gas production facilities in that downstream equipment, such as compressors, are completely dependent on the efficient performance of these multiphase separators. The literature on this critical unit operation, multiphase separators, abounds with macro studies and design methodologies for two‐ and three‐phase vertical and horizontal separators. There are very few studies that provide the micro details of the actual separation process. In fact, the popular classic methods for separator design, mostly due to a lack of a usable mathematical model for estimation of droplet ‘separation velocities’, do result in a conservative design and would specify extremely oversized separators. In order to reflect the current situation and address recent findings, this study will review the important literature on design and CFD simulation of multiphase separators. This review will show the benefits that CFD analyses can provide in optimising the design of new separators and solving problems with existing designs. © 2011 Canadian Society for Chemical Engineering
Design and Synthesis of Novel Pyrazole‐based Lp‐PLA2 Inhibitors
Authors: Wang Yi , Xu Weiren , Shao Hua , Xie Yafei , Wang Jianwu 
Published: October 2011

AbstractA series of novel pyrazole‐based lipoprotein‐associated phospholipase A2 (Lp‐PLA2) inhibitors have been designed and synthetized by a variety of acetophenones via a 10‐step convergent approach. The synthetic approach is carefully optimized, and an unsuccessful alternative route is also discussed. The in vitro biological activity reveals that all the synthesized compounds are potent Lp‐PLA2 inhibitors with compound 13b being the most potent one (Lp‐PLA2, IC50=1.5 nmol/L).
QSRR Study of GC Retention Indices of Volatile Compounds Emitted from Mosla chinensis Maxim by Multiple Linear Regression
Authors: Cao Hui , Li Zuguang , Chen Xiaozhen 
Published: October 2011

AbstractThe volatile compounds emitted from Mosla chinensis Maxim were analyzed by headspace solid‐phase microextraction (HS‐SPME) and headspace liquid‐phase microextraction (HS‐LPME) combined with gas chromatography‐mass spectrometry (GC‐MS). The main volatiles from Mosla chinensis Maxim were studied in this paper. It can be seen that 61 compounds were separated and identified. Forty‐nine volatile compounds were identified by SPME method, mainly including myrcene, α‐terpinene, p‐cymene, (E)‐ocimene, thymol, thymol acetate and (E)‐β‐farnesene. Forty‐five major volatile compounds were identified by LPME method, including α‐thujene, α‐pinene, camphene, butanoic acid, 2‐methylpropyl ester, myrcene, butanoic acid, butyl ester, α‐terpinene, p‐cymene, (E)‐ocimene, butane, 1,1‐dibutoxy‐, thymol, thymol acetate and (E)‐β‐farnesene. After analyzing the volatile compounds, multiple linear regression (MLR) method was used for building the regression model. Then the quantitative structure‐retention relationship (QSRR) model was validated by predictive‐ability test. The prediction results were in good agreement with the experimental values. The results demonstrated that headspace SPME‐GC‐MS and LPME‐GC‐MS are the simple, rapid and easy sample enrichment technique suitable for analysis of volatile compounds. This investigation provided an effective method for predicting the retention indices of new compounds even in the absence of the standard candidates.
An Efficient One‐pot Synthesis of Pyrazolone Derivatives Promoted by Acidic Ionic Liquid
Authors: Zang Hongjun , Su Qiuhong , Guo Song , Mo Yingming , Cheng Bowen 
Published: October 2011

AbstractA new class of pyrazolone derivatives has been isolated in good to excellent yields from the 2:1 condensation reaction between 3‐methyl‐1‐phenyl‐5‐pyrazolone and arylaldehydes in the presence of ionic liquid [HMIM]HSO4. The compounds were characterised by their IR, NMR spectra, MS and elemental analyses. The important features of the methodology are a wide application range of substrates, higher yields and shorter reaction time.
Amide Hydrolysis Reaction Catalyzed by KF/Al2O3 under Microwave Irradiation and Solvent Free Conditions
Authors: Zhang Xiuli , Luo Kai , Chen Wei , Wang Lei 
Published: October 2011

AbstractA microwave‐enhanced hydrolysis of amides utilizing KF/Al2O3 in the absence of solvents has been developed. Amines are produced in excellent yields along with the corresponding carboxylic acids.