bluuebunny/crossref_metadata_2025_split huggingface dataset:
FILLING GAPS IN ECOLOGICAL TIME SERIES BY MEANS OF TWIN SURROGATES
Authors: FACCHINI ANGELO , MOCENNI CHIARA 
Published: June 2011

This paper addresses the problem of reconstructing missing data in time series by the twin surrogates method. We consider a set of time series, collected by a sensor network, representing the same state variable measured at different locations of a spatially distributed system. Assuming the presence of coherent dynamics among the available data, the method of twins is applied as an input–output model using the information provided by the complete time series for filling the incomplete recordings. The method is applied to the measurements of Dissolved Oxygen concentrations collected in the lagoon of Orbetello (Italy) and to time series obtained from the logistic chaotic map. Both cases show satisfactory performances in the reconstruction of missing data.
Oceanic lithospheric mantle beneath the continental crust of the Chinese Altai
Authors: Yuan Chao , Sun Min , Xu Yigang , Zhao Guochun , Xiao Wenjiao , Long Xiaoping , Yin Jiyuan 
Published: June 2011

Abstract:
Although subduction–accretion is proposed as a major regime in making new continental crust, how the lithospheric mantle forms remains unclear. Formed after the closure of the Palaeo-Asian Ocean, the Ashele basalt shows normal mid-ocean ridge basalt (N-MORB)-like characteristics with light REE-depleted patterns and extremely low contents of high field strength elements. The low Zr/Y and Nb/Y ratios of the basalt are significantly different from those of asthenosphere-derived melts, and the excess Eu and Sr suggest that the basalt was probably derived from accreted oceanic lithospheric mantle. The presence of the N-MORB-like terrestrial basalt implies that subduction–accretion is an effective mechanism in building the refractory lithospheric mantle of Phanerozoic continents.

Supplementary material:

A photograph of the outcrop, and age and geochemical data are available at
http://www.geolsoc.org.uk/SUP18464
.
Widespread Cretaceous inversion event in northern Spain: evidence from subsurface and palaeomagnetic data
Authors: Soto Ruth , Casas-Sainz Antonio M. , Villalaín Juan J. 
Published: June 2011

Abstract:
In this paper we present geological evidence of a mid-Cretaceous inversion event in the Polientes basin (northern Iberian plate) based on geological data. Analysis of seismic profiles across the basin indicates that this tectonic event resulted in the uplift of the basin depocentre and the formation of an upright gentle anticline before Cenomanian times. The presence of a pre-Alpine, syntectonic remagnetization in the Jurassic and Lower Cretaceous rocks of the Polientes basin allows us to define the geometry of the basin at the time between this early inversion event and the main Alpine compressional period. The early inversion in the Polientes basin is consistent with a transpressional tectonic setting, contemporaneous with the left-lateral strike-slip movement of Iberia with respect to Europe. This study shows the successful use of two approaches to unravel the geodynamic scenario of the northern Iberian plate during the Cretaceous, which was later obliterated during the Tertiary Pyrenean orogeny.
Structure and
40
Ar/
39
Ar thermochronology of an ultrahigh-pressure transition in western Norway
Authors: Young D.J. , Hacker B.R. , Andersen T.B. , Gans P.B. 
Published: June 2011

Abstract:

The Nordfjord region of western Norway hosts an archetypal subducted crustal section, underpinned by ultrahigh-pressure (UHP) eclogite, overlain by Devonian sediments, and cored by a crustal-scale extensional shear zone. Structural mapping reveals two distinct displacement zones that played different roles during the formation and exhumation of this section: (1) the Sandane Shear Zone is a NW-dipping, amphibolite-facies, high-strain zone near the base of the eclogite-bearing crust that separates allochthonous units from underlying crystalline basement; it may have originated during early thrusting, but was overprinted by top-to-the-west extensional fabrics at lower crustal depths; (2) structurally above this, the Nordfjord–Sogn Detachment Zone is a top-to-the-west, amphibolite- to greenschist-facies detachment shear zone within allochthonous units that defines the upper boundary of the eclogitized crust and was responsible for exhumation through at least mid-crustal depths. Muscovite
40
Ar/
39
Ar ages suggest that amphibolite-facies deformation below the Nordfjord–Sogn Detachment was mostly finished by
c
. 397 Ma, whereas muscovite ages from the deeper parts of the UHP domain indicate that it cooled after 390 Ma. During exhumation through the middle crust, west-directed stretching was accompanied by north–south folding. Late sinistral transpressional faulting in the middle to upper crust truncated the earlier folds and shear zones.

Supplementary material:

Complete
40
Ar/
39
Ar data and a summary geological map of the Nordfjord region are available at
http://www.geolsoc.org.uk/SUP18460
.
The emplacement of the Palaeogene Mourne Granite Centres, Northern Ireland: new results from the Western Mourne Centre
Authors: Stevenson C.T.E. , Bennett N. 
Published: June 2011

Abstract:

There is a basic assumption that the upper crustal point of magma emplacement overlies the point where magma was generated. This contribution discusses the concept of lateral magma movement in the upper crust based on the Mourne Granite Centres, Northern Ireland. We report anisotropy of magnetic susceptibility fabric data from the Western Mourne Centre that indicate SSW to NNE inflow in this centre, parallel to the Eastern Centre. This suggests that these two centres share a common feeder zone outside the Mourne area
c
. 20 km to the south, coincident with a
c
. 50 mGal gravity anomaly that may be caused by an unexposed mafic pluton. The links between mafic and felsic magmas in this region, and the coincidence of the projected Mourne granite feeder zone and the possible buried mafic pluton lead to a model in which the Mourne granites were emplaced in a NNE direction as two gently dipping sheets from this unexposed mafic body. From this we develop a model that incorporates existing geophysics and known tectonic framework and involves an interconnected upper crustal network of Early Palaeogene igneous intrusion pathways fed from a common tectonically controlled, and probably long-lived, deeply penetrating feeder zone.

Supplementary material:

Anisotropy of magnetic susceptibility data, thermomagnetic analyses and a thin section showing magnetite in biotite cleavage are available at
http://www.geolsoc.org.uk/SUP18458
.
Insights of dyke emplacement mechanics from detailed 3D dyke thickness datasets
Authors: Kavanagh J.L. , Sparks R.Stephen J. 
Published: June 2011

Abstract:
Dyke thickness datasets offer new insights into the detailed 3D geometry of dyke swarms and an exceptional opportunity to evaluate theoretical emplacement models. The Swartruggens kimberlite dyke swarm extends over 7 km along strike and intrudes a dolerite, quartzite, shale and andesitic lava succession. The Star kimberlite dykes cut shales and sandstones, intersect a large dolerite sill and extend 15 km along strike. Both dyke swarms comprise anastomosing en echelon segments, each several hundred metres long. In total 1532 Swartruggens dyke thickness measurements were taken, to 750 m below the surface over a 250 m depth range, and 3354 Star dyke thickness measurements were taken over a 520 m depth range. The Swartruggens dyke thicknesses are 0.05–1.95 m (mean 0.64 m), whereas the Star kimberlites range from <0.01 to 1.6 m thick (mean 0.40 m). Two-dimensional models of elastic cracks in a homogeneous, isotropic material subject to constant magmatic over-pressure poorly describe the dyke thickness variation, which is complex and varies along both breadth and length. The Swartruggens dyke segments thicken toward their terminations along strike, which represent regions where stresses were focused. Towards the surface, rock deformation is increasingly difficult to recover as inelastic processes such as host-rock brecciation, stoping, and magma solidification become important.
Mid- to Late Cambrian docking of the Río de la Plata craton to southwestern Gondwana: age constraints from U–Pb SHRIMP detrital zircon ages from Sierras de Ambato and Velasco (Sierras Pampeanas, Argentina)
Authors: Verdecchia Sebastián O. , Casquet Cesar , Baldo Edgardo G. , Pankhurst Robert J. , Rapela Carlos W. , Fanning Mark , Galindo Carmen 
Published: June 2011

Abstract:

The Early Palaeozoic stratigraphy and tectonic history of the Eastern Sierras Pampeanas of central Argentina are complicated by metamorphism and deformation resulting from the Pampean (545–510 Ma) and Famatinian (490–440 Ma) orogenies. We report U–Pb sensitive high-resolution ion microprobe dating of detrital zircons in two metasedimentary successions exposed at Quebrada de La Cébila (
c
. 28°45'S, 66°25'W): the Ambato and the La Cébila metamorphic complexes. The Ambato zircons record age peaks corresponding to Pampean (530 ± 10 Ma), Brasiliano (
c
. 570 and
c
. 640 Ma), Grenville (
c
. 950 to
c
. 1025 Ma) and minor Neoarchaean ages. Similar peaks are also apparent in the La Cébila sample but it additionally contains Palaeoproterozoic zircons (
c
. 2.1 Ga) corresponding to the age of the Rio de la Plata craton, from which they are considered to have been sourced. Our interpretation is that the protolith of the Ambato complex was deposited prior to juxtaposition with the craton and is older than the Early Ordovician La Cébila metamorphic complex. We infer that the craton reached its current relative position in the Mid- to Late Cambrian, after the main Pampean tectonothermal event (530–520 Ma) and before deposition of the La Cébila protolith and the Achavil Formation (Sierra de Famatina), which contain comparable detrital zircon populations.
The growth of the Zimbabwe Craton during the late Archaean: an ion microprobe U–Pb zircon study
Authors: Rollinson Hugh R. , Whitehouse Martin 
Published: June 2011

Abstract:

U–Pb zircon ages obtained by ion microprobe are presented for late Archaean granitoids from the Zimbabwe Craton and the North Marginal Zone of the Limpopo Belt. Similar ages of crust formation in the felsic gneisses of the Zimbabwe Craton and the felsic granulites of the North Marginal Zone support the view, previously argued on geological grounds, that they represent the middle and lower crustal layers respectively of the Zimbabwe Craton. Zircons from the southern margin of the Zimbabwe Craton and the northern part of the North Marginal Zone contain old cores, confirming the presence of an old (
c
. 3.5 Ga) nucleus to the Zimbabwe Craton and indicating that the areal extent of this old nucleus is greater than has been hitherto supposed. Thus late Archaean crustal growth involved both the reworking of and the addition of new magmas to this old crustal nucleus. At 2.7 Ga crustal growth was contemporaneous with plume volcanism in the greenstone belts. In contrast, crustal growth at 2.74, 2.67, 2.64 and ?2.62 Ga was focused at the margins of the ‘old craton' and may be related to Andean style continental margin magmatism. Lower crustal melting at 2.61–2.59 Ga led to the emplacement of granitoids in the upper crust.

Supplementary material:

A summary of previously published U–Pb zircon geochronology for the Zimbabwe Craton and the North Marginal Zone of the Limpopo Belt, field relationships and sample localities for the samples used in this study, and U–Th–Pb secondary ionization mass spectrometry data are available at
www.geolsoc.org.uk/SUP18466
.
Structural controls on mud volcano vent distributions: examples from Azerbaijan and Lusi, east Java
Authors: Roberts Katie S. , Davies Richard J. , Stewart Simon A. , Tingay Mark 
Published: June 2011

Abstract:

Structural mapping, nearest neighbour and two-point azimuth statistical analysis of mud volcano vent distributions from nine examples in Azerbaijan and the Lusi mud volcano in east Java are described. Distributions are non-random, forming alignments subparallel to faults within anticlines, ring faults, conjugate faults and detachment faults; this finding confirms a spatial relationship and supports a model for subsurface flow along these features as well as showing fractionation at depth. As fracture and fault orientations are related to structures such as anticlines and the
in situ
stress state they are therefore predictable. We use vent distributions in Azerbaijan, where the structural geology is well constrained, to propose what controls the distribution of 169 vents at the Lusi mud volcano. This mud volcano system shows evidence for initial eruptions along a NE–SW trend, parallel to the Watukosek fault, changing to eruptions that follow east–west trends, subparallel to regional fold axes. Our analysis indicates that regions east and west of the Lusi mud volcano are more likely to be affected by new vents than those to the north and south, owing to probable onset of elongate caldera collapse within a 10 km diameter of the central vent.
Truncated ErbB2 Expressed in Tumor Cell Nuclei Contributes to Acquired Therapeutic Resistance to ErbB2 Kinase Inhibitors
Authors: Xia Wenle , Liu Zuguo , Zong Rongrong , Liu Leihua , Zhao Sumin , Bacus Sarah S. , Mao Yubin , He Jia , Wulfkuhle Julia D. , Petricoin Emanuel F. , Osada Takuya , Yang Xiao-Yi , Hartman Zachary C. , Clay Timothy M. , Blackwell Kimberly L. , Lyerly Herbert K. , Spector Neil L. 
Published: June 2011

Abstract
ErbB2 tyrosine kinase inhibitors (TKI) block tyrosine autophosphorylation and activation of the full-length transmembrane ErbB2 receptor (p185ErbB2). In addition to p185ErbB2, truncated forms of ErbB2 exist in breast cancer cell lines and clinical tumors. The contribution of these truncated forms, specifically those expressed in tumor cell nuclei, to the development of therapeutic resistance to ErbB2 TKIs has not been previously shown. Here, we show that expression of a 95-kDa tyrosine phosphorylated form of ErbB2, herein referred to as p95L (lapatinib-induced p95) was increased in ErbB2+ breast cancer cells treated with potent ErbB2 TKIs (lapatinib, GW2974). Expressed in tumor cell nuclei, tyrosine phosphorylation of p95L was resistant to inhibition by ErbB2 TKIs. Furthermore, the expression of p95L was increased in ErbB2+ breast cancer models of acquired therapeutic resistance to lapatinib that mimic the clinical setting. Pretreatment with proteasome inhibitors blocked p95L induction in response to ErbB2 TKIs, implicating the role of the proteasome in the regulation of p95L expression. In addition, tyrosine phosphorylated C-terminal fragments of ErbB2, generated by alternate initiation of translation and similar in molecular weight to p95L, were expressed in tumor cell nuclei, where they too were resistant to inhibition by ErbB2 TKIs. When expressed in the nuclei of lapatinib-sensitive ErbB2+ breast cancer cells, truncated ErbB2 rendered cells resistant to lapatinib-induced apoptosis. Elucidating the function of nuclear, truncated forms of ErbB2, and developing therapeutic strategies to block their expression and/or activation may enhance the clinical efficacy of ErbB2 TKIs. Mol Cancer Ther; 10(8); 1367–74. ©2011 AACR.
Osteopontin Stimulates Preneoplastic Cellular Proliferation Through Activation of the MAPK Pathway
Authors: Luo Xianmin , Ruhland Megan K. , Pazolli Ermira , Lind Anne C. , Stewart Sheila A. 
Published: June 2011

Abstract
Alterations in the microenvironment collaborate with cell autonomous mutations during the transformation process. Indeed, cancer-associated fibroblasts and senescent fibroblasts stimulate tumorigenesis in xenograft models. Because senescent fibroblasts accumulate with age, these findings suggest that they contribute to age-related increases in tumorigenesis. Previously we showed that senescence-associated stromal-derived osteopontin contributes to preneoplastic cell growth in vitro and in xenografts, suggesting that it impacts neoplastic progression. Analysis of fibroblasts within premalignant and malignant skin lesions ranging from solar/actinic keratosis to squamous cell carcinoma revealed they express osteopontin. Given the stromal expression of osteopontin, we investigated how osteopontin impacts preneoplastic cell growth. We show that osteopontin promotes preneoplastic keratinocyte cellular proliferation and cell survival through the CD44 cell receptor and activation of the MAPK pathway. These data suggest that stromal-derived osteopontin impacts tumorigenesis by stimulating preneoplastic cell proliferation thus allowing expansion of initiated cells in early lesions. Mol Cancer Res; 9(8); 1018–29. ©2011 AACR.
Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium
Authors: Iwanicki Marcin P. , Davidowitz Rachel A. , Ng Mei Rosa , Besser Achim , Muranen Taru , Merritt Melissa , Danuser Gaudenz , Ince Tan , Brugge Joan S. 
Published: June 2011

Abstract
Dissemination of ovarian tumors involves the implantation of cancer spheroids into the mesothelial monolayer on the walls of peritoneal and pleural cavity organs. Biopsies of tumors attached to peritoneal organs show that mesothelial cells are not present under tumor masses. We have developed a live, image-based in vitro model in which interactions between tumor spheroids and mesothelial cells can be monitored in real time to provide spatial and temporal understanding of mesothelial clearance. In this article, we provide evidence that ovarian cancer spheroids use integrin- and talin-dependent activation of myosin and traction force to promote displacement of mesothelial cells from underneath a tumor cell spheroid. These results suggest that ovarian tumor cell clusters gain access to the submesothelial environment by exerting force on the mesothelial cells lining target organs, driving migration and clearance of the mesothelial cells.
Significance: This study uses time-lapse video microscopy to decipher cellular events associated with ovarian tumor cell intercalation of mesothelial cell layers. Ovarian cancer clusters were found to use actomyosin-generated force to physically displace mesothelial cells and gain access to the submesothelial environment. Blockade of force-conducting molecules, including α5 integrin, talin I, and nonmuscle myosin II, in cancer cells abrogated mesothelial displacement from underneath attached cancer spheroids. Cancer Discovery; 1(2); 144–57. ©2011 AACR.
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Working Memory and the Hippocampus
Authors: Baddeley Alan , Jarrold Christopher , Vargha-Khadem Faraneh 
Published: June 2011

Abstract
A number of studies suggest an important role for the hippocampus in tasks involving visuospatial or relational working memory. We test the generality of this proposal across tasks using a battery designed to investigate the various components of working memory, studying the working memory performance of Jon, who shows a bilateral reduction in hippocampal volume of approximately 50%, comparing him to a group of 48 college students. We measure performance on four complex working memory span measures based on combining visuospatial and verbal storage with visuospatial or verbal concurrent processing as well as measuring Jon's ability to carry out the component storage and processing aspects of these tasks. Jon performed at a consistently high level across our range of tasks. Possible reasons for the apparent disparity between our own findings and earlier studies showing a hippocampal deficit are discussed in terms of both the potential differences in the demands placed on relational memory and of the proposed distinction between egocentric and allocentric visuospatial processing.
What Does Ipsilateral Delay Activity Reflect? Inferences from Slow Potentials in a Lateralized Visual Working Memory Task
Authors: Arend Anna M. , Zimmer Hubert D. 
Published: June 2011

Abstract
In the lateralized change detection task, two item arrays are presented, one on each side of the display. Participants have to remember the items in the relevant hemifield and ignore the items in the irrelevant hemifield. A difference wave between contralateral and ipsilateral slow potentials with respect to the relevant items, the contralateral delay activity, can be calculated. As its amplitude varies with the number of items held in working memory (WM) and reaches its asymptote with WM capacity, it is considered a pure neural correlate of visual WM load. However, in addition to this contralateral delay activity, load-dependent activity has also been observed over the hemisphere ipsilateral to the relevant hemifield, suggesting that the ipsilateral hemisphere is also involved in memory-related processes. This ipsilateral activity might either reflect a bilateral processing of relevant or else a lateralized processing of irrelevant, to-be-filtered-out items. As in the lateralized change detection task, the number of items on both sides of the display is typically identical, it was not possible to decide between these alternatives yet. To disentangle the influence of relevant and irrelevant items, we orthogonally varied the number of both types of items. Processing of relevant items caused purely contralateral load-dependent activity. Ipsilateral slow potentials were influenced by the number of irrelevant items only if visual WM load was low, but not if it was high. This suggests that whether irrelevant items are processed or filtered out depends on visual WM load.
Neural Correlates of Subsecond Time Distortion in the Middle Temporal Area of Visual Cortex
Authors: Sadeghi Navid G. , Pariyadath Vani , Apte Sameer , Eagleman David M. , Cook Erik P. 
Published: June 2011

Abstract
How does the brain represent the passage of time at the subsecond scale? Although different conceptual models for time perception have been proposed, its neurophysiological basis remains unknown. We took advantage of a visual duration illusion produced by stimulus novelty to link changes in cortical activity in monkeys with distortions of duration perception in humans. We found that human subjects perceived the duration of a subsecond motion pulse with a novel direction longer than a motion pulse with a repeated direction. Recording from monkeys viewing identical motion stimuli but performing a different behavioral task, we found that both the duration and amplitude of the neural response in the middle temporal area of visual cortex were positively correlated with the degree of novelty of the motion direction. In contrast to previous accounts that attribute distortions in duration perception to changes in the speed of a putative internal clock, our results suggest that the known adaptive properties of neural activity in visual cortex contributes to subsecond temporal distortions.