bluuebunny/crossref_metadata_2025_split huggingface dataset:
Culturally Adapting an Evidence‐Based Parenting Intervention for Latino Immigrants: The Need to Integrate Fidelity and Cultural Relevance
Authors: Parra Cardona Jose Ruben , Domenech‐Rodriguez Melanie , Forgatch Marion , Sullivan Cris , Bybee Deborah , Holtrop Kendal , Escobar‐Chew Ana Rocio , Tams Lisa , Dates Brian , Bernal Guillermo 
Published: March 2012

摘要拉丁裔构成美国最大的少数族群。然而,文化适应及循证养育干预的宣传在拉丁裔族群中依然不足,尽管有大量研究表明了这些干预的长期正面影响。本文有三重目的:(a)证明将文化适应研究作为在拉丁裔族群中推广有效干预关键措施的重要性;(b)描述针对拉丁裔移民进行的依照父母管理培训(PMT)原则,且目的为从文化上适应循证干预的一个预防研究项目的最初步骤;以及(c)根据本研究的初始可行性和文化接受发现探讨推进文化适应预防实践与研究的种种意义。
Scaffolding a Community of Competent Practitioners: Positioning and Agency in a Training Program for Narrative Counseling
Authors: Gremillion Helen , Cheshire Aileen , Lewis Dorothea 
Published: March 2012

摘要本文探讨新西兰一叙事咨询研究生培训项目的学习经历构架。本文作者利用定位理论识别学生在学习与行为能动性中的转变,这些转变有助于建立一个愈来愈有技巧性的、由同龄人一起创造的学习环境。我们描述了课程中按特定顺序出现的一组练习和一个关键任务;我们相信这些练习和任务可让学生踏上具有行为能动性的位置,从而最终促使一个有称职学员医师的社区出现。我们也描述了我们自己在这个项目中作为教师所经历的定位经历。我们建议,任何时候都应把我们自己的定向与学生定向的种种可能紧密联系起来。我们承认教室里的权力关系,并探索了种种将后结构主义咨询实践与这些实践的教学相匹配的方法。
Development and Dissemination of Collaborative Family‐Oriented Services: The Case of Community/Day Residential Care in Israel
Authors: Elizur Yoel 
Published: March 2012

摘要家庭导向项目的开创、发展及传播是突显家庭治疗对精神//身体健康和社会服务所作贡献的主线。这些具有挑战性的任务对生态系统型观念、支持性大环境,以及一系列技能都有要求。本文通过考察不同生态层次过程来描述以色列社区及日间住宿照顾的演变:国家社会政策的制定与执行、对两个家庭导向设施的持续跟踪(其中一个发展兴旺,另一个则最终关闭),以及为一个有三个孩子家庭提供的住宿照顾。对此多级数据的分析显示了四个对家庭导向项目有巨大影响的促进/阻碍因素:国家与地方社会政治职业管理的支持、项目管理自主性、工作人员的培训、支持和发展,以及建立并培育家庭导向组织结构与文化的有效设施领导。
Microvascular Flow Modeling using In Vivo Hemodynamic Measurements in Reconstructed 3D Capillary Networks
Authors: FRASER GRAHAM M. , GOLDMAN DANIEL , ELLIS CHRISTOPHER G. 
Published: March 2012

Please cite this paper as: Fraser GM, Goldman D, Ellis CG. Microvascular flow modeling using in vivo hemodynamic measurements in reconstructed 3D capillary networks. Microcirculation 19: 510–520, 2012.AbstractObjective:  We describe a systematic approach to modeling blood flow using reconstructed capillary networks and in vivo hemodynamic measurements. Our goal was to produce flow solutions that represent convective O2 delivery in vivo.Methods:  Two capillary networks, I and II (84 × 168 × 342 and 70 × 157 × 268 μm3), were mapped using custom software. Total network red blood cell supply rate (SR) was calculated from in vivo data and used as a target metric for the flow model. To obtain inlet hematocrits, mass balances were applied recursively from downstream vessels. Pressure differences across the networks were adjusted to achieve target SR. Baseline flow solutions were used as inputs to existing O2 transport models. To test the impact of flow redistribution, asymmetric flow solutions (Asym) were generated by applying a ± 20% pressure change to network outlets.Results:  Asym solutions produced a mean absolute difference in SR per capillary of 27.6 ± 33.3% in network I and 33.2 ± 40.1% in network II vs. baseline. The O2 transport model calculated mean tissue PO2 of 28.2 ± 4.8 and 28.1 ± 3.5 mmHg for baseline and 27.6 ± 5.2 and 27.7 ± 3.7 mmHg for Asym.Conclusions:  This outcome illustrates that moderate changes in flow distribution within a capillary network have little impact on tissue PO2 provided that total SR remains unchanged.
It is Not Just Hardware and Software, Anymore! Human Systems Integration in US Submarines
Authors: HAMBURGER PATRICIA , MISKIMENS DAVID , TRUVER SCOTT 
Published: March 2012

AbstractUntil recently, the Navy's approach to designing, engineering, and acquiring complex weapon systems did not routinely or completely include the human “warrior” as an integral part of the system. Rather, the Navy viewed systems as combinations of hardware and software. The results were often less‐than‐optimal capability and high life‐cycle cost—and, sometimes, even mission failure. Given the high rate of technological change and the need to rein in cost in the face of increasingly constrained budgets, the Navy and the other services have increasingly embraced the need to consider human‐performance capabilities and limitations up front and on an equal footing with hardware and software—as integral elements in both new‐acquisition and technology‐refresh programs. The US Submarine Force has championed human systems integration (HSI). HSI is a specialized engineering discipline that takes human limitations and capabilities fully into account to influence system design and engineering early in the research, development, and acquisition process, thereby helping to ensure the highest overall performance at the lowest total ownership cost. Implementation of HSI has involved new partnerships with unlikely partners such as the audio equipment company Bose, game‐makers, the visual‐reality industry, physiologists, and psychologists. Nowhere has this been more apparent than in the Virginia (SSN‐774)‐Class Nuclear Attack Submarine Program.
The correlations between alteration of p16 gene and clinicopathological factors and prognosis in squamous cell carcinomas of the buccal mucosa
Authors: Dong Yuying , Wang Jie , Dong Fusheng , Wang Xu , Zhang Yinghuai 
Published: March 2012

J Oral Pathol Med (2012) 41: 463–469Objective:  To evaluate relationships between the alteration of p16 gene and the clinical status and prognosis of the patients with squamous cell carcinoma of the buccal mucosa.Methods:  Thirty buccal cancers were included in the analysis. Deletion analysis was performed by PCR. Point mutation analysis was used by PCR‐SSCP and direct sequencing. Methylation‐specific PCR methods were adopted for the evaluation of p16 methylation. The correlation between alteration of p16 gene and clinicopathological factors buccal cancer was evaluated by Fisher’s exact test. Kaplan–Meier and Cox regression were used to investigate the relationship between p16 alteration and survival time.Results:  The frequency of p16 alteration was 63.3% in buccal carcinomas. P16 deletion was associated significantly with tumor size (P = 0.01). P16 point mutation was associated significantly with differentiation (P = 0.006). P16 methylation was associated significantly with nodes metastasis (P = 0.027). The overall survival rate of 30 buccal carcinomas was 53.3%. The Log‐rank test (P = 0.021) and univariate Cox regression analysis (P = 0.030) revealed that p16 methylation was significantly associated with the overall survival rate. Multivariate analysis showed that p16 deletion, p16 mutation, and p16 methylation were not statistically significant.Conclusions:  The alterations of p16 gene may play a major role in malignancy and development and metastases of buccal carcinoma and may be an excellent marker of aggressive clinical behavior. P16 methylation has a prognostic value in buccal carcinoma but not an independent prognosis factor. P16 point mutation and p16 deletion have not prognostic significance in buccal carcinoma.
Plant species richness: the world records
Authors: Wilson J. Bastow , Peet Robert K. , Dengler Jürgen , Pärtel Meelis 
Published: March 2012

AbstractQuestionsThe co‐existence of high numbers of species has always fascinated ecologists, but what and where are the communities with the world records for plant species richness? The species–area relationship is among the best‐known patterns in community ecology, but does it give a consistent global pattern for the most saturated communities, the global maxima?LocationThe world.MethodsWe assembled the maximum values recorded for vascular plant species richness for contiguous areas from 1 mm2 up to 1 ha. We applied the power function to relate maximal richness to area and to make extrapolations to the whole Earth.ResultsOnly two community types contain global plant species maxima. The maxima at smaller spatial grain were from oligo‐ to meso‐trophic, managed, semi‐natural, temperate grasslands (e.g. 89 species on 1 m2), those at larger grains were from tropical rain forests (e.g. 942 species on 1 ha). The maximum richness values closely followed a power function with z = 0.250: close to Preston's ‘canonical’ value of 0.262. There was no discernable difference between maxima using rooted presence (i.e. including only plants rooted in the plot) vs shoot presence (i.e. including any plant with physical cover over the plot). However, shoot presence values must logically be greater, with the curves flattening out at very small grain, and there is evidence of this from point quadrats. Extrapolating the curve to the terrestrial surface of the Earth gave a prediction of 219 204 vascular plant species, surprisingly close to a recent estimate of 275 000 actual species.ConclusionsVery high richness at any spatial grain is found only in two particular habitat/community types. Nevertheless, these high richness values form a very strong, consistent pattern, not greatly affected by the method of sampling, and this pattern extrapolates amazingly well. The records challenge ecologists to consider mechanisms of species co‐existence, answers to the ‘Paradox of the Plankton’.
Effect on emergency department efficiency of an accelerated diagnostic pathway for the evaluation of chest pain
Authors: Meek Robert , Braitberg George , Nicolas Caroline , Kwok Gabriel 
Published: March 2012

AbstractObjective: To compare ED efficiency measures between a trial period using an accelerated diagnostic pathway (ADP) for chest pain evaluation, and a control period using a traditional diagnostic pathway (TDP).Methods: The TDP used cardiac Troponin I assays at arrival and 6 h. The ADP used point‐of‐care multimarker (myoglobin, creatine kinase‐MB fraction and cardiac Troponin I) assays at arrival and 2 h. Outcomes for consecutive eligible patients included ED length of stay (LOS), discharges and admissions within 4 and 8 h, ED occupancy and cardiac cubicle throughput.Results: There were 413 and 258 eligible patients during the 81 day TDP and 66 day ADP periods. The ED LOS for chest pain patients was reduced in the ADP period for both discharged patients (median 297 [interquartile range {IQR} 230–437]vs 545 [IQR 457–677] min, P < 0.0001) and admitted patients (median 609.5 [IQR 464–857]vs 733.5 [IQR 532–1070] min, P= 0.007). For the whole ED, the percentage of patients discharged or admitted within 4 or 8 h and ED occupancy were similar between periods. Cardiac cubicle throughput increased during the ADP period (217 [95% confidence interval 209.6–224.4]vs 188 [95% confidence interval 174.5–201.8] patients per week, P= 0.005).Conclusions: The ADP utilizing point‐of‐care multimarkers led to significantly shorter ED LOS for both discharged and admitted chest pain patients. This was associated with increased cardiac cubicle throughput, but improvements in other whole ED performance indicators were not demonstrated.
Sexual Dysfunctions in Men Affected by Autoimmune Addison's Disease Before and After Short-Term Gluco- and Mineralocorticoid Replacement Therapy
Authors: Granata Antonio , Tirabassi Giacomo , Pugni Valeria , Arnaldi Giorgio , Boscaro Marco , Carani Cesare , Balercia Giancarlo 
Published: March 2012

ABSTRACT

Introduction
There is evidence suggesting that autoimmune Addison's disease (AD) could be associated with sexual dysfunctions probably caused by gluco- and mineralocorticoid deficiency; however, no study has yet treated this subject in males.

Aim
To evaluate male sexuality and psychological correlates in autoimmune AD before and after gluco- and mineralocorticoid replacement therapy.

Methods
Twelve subjects with a first diagnosis of autoimmune AD were studied before (baseline) and 2 months after (recovery phase) initiating hormone replacement therapy.

Main Outcome Measures
Erectile function (EF), orgasmic function (OF), sexual desire (SD), intercourse satisfaction (IS), overall satisfaction (OS), depression, and anxiety were studied using a number of questionnaires (International Index of Erectile Function, Beck Depression Inventory, and Spielberger State-Trait Anxiety Inventory); clinical, biochemical, and hormone data were included in the analysis.

Results
At baseline, low values were found for EF, OF, SD, IS, and OS and high values for depression and anxiety; all of these parameters improved significantly in the recovery phase compared with baseline. EF variation between the two phases correlated significantly and positively with the variation of serum cortisol, urinary free cortisol, systolic blood pressure, and diastolic blood pressure and inversely with that of upright plasma renin activity. Multiple linear regression analysis using EF variation as dependent variable confirmed the relationship of the latter with variation of serum cortisol, urinary free cortisol, and upright plasma renin activity but not with variation of systolic and diastolic blood pressure.

Conclusions
Our study showed that onset of autoimmune AD in males is associated with a number of sexual dysfunctions, all reversible after initiating replacement hormone therapy; cortisol and aldosterone deficiency seems to play an important role in the genesis of erectile dysfunction although the mechanism of their activity is not clear.
Postcoital Vaginal Rupture in a Young Woman with No Prior Pelvic Surgery
Authors: Austin Jennifer M. , Cooksey Christie M. , Minikel Laura L. , Zaritsky Eve F. 
Published: March 2012

ABSTRACT

Introduction
Reports of postcoital vaginal rupture in the literature are limited to cases involving women who are postmenopausal, have recently undergone pelvic surgery, or have suffered genitourinary trauma.

Aim
We report a case of postcoital vaginal rupture in a 23-year-old woman with no prior surgical history who complained of acute onset, severe vaginal pain after consensual intercourse.

Results
Examination under anesthesia revealed a 6-cm laceration of the posterior fornix, which extended into the abdominal cavity. The laceration was repaired using a combined vaginal and laparoscopic approach.

Conclusions
Coitus-induced vaginal rupture in a reproductive aged woman with no prior pelvic surgery or other risk factors is a rare clinical presentation. Prior reports of rupture in premenopausal women have recommended repair via laparotomy. This case documents successful transvaginal and laparoscopic repair, and reviews the etiological mechanisms for coitus-induced injury.
Sexual Abuse History in GI Illness, How Do Gastroenterologists Deal with it?
Authors: Nicolai Melianthe P.J. , Fidder Herma H. , Beck Jack J.H. , Bekker Milou D. , Putter Hein , Pelger Rob C.M. , van Driel Mels F. , Elzevier Henk W. 
Published: March 2012

ABSTRACT

Introduction
Data support an increased prevalence of sexual abuse (SA) among patients with gastrointestinal (GI) complaints. Sexual abuse causes multiple symptoms related to pelvic floor and stress mediated brain-gut dysfunctions. Treating these patients asks for a holistic approach, using centrally targeted interventions. However, gastroenterologists have never been surveyed regarding their practice patterns and constraints about inquiring into SA.

Aim
To evaluate whether gastroenterologists address SA in their daily practice and to evaluate their knowledge regarding the implications of SA in GI illness.

Methods
A 42-item anonymous questionnaire was mailed to all 402 members of the Dutch Society of Gastroenterology (gastroenterologists and fellows in training). The questionnaire addressed SA and pelvic-floor-related complaints.

Main Outcome Measures
The results of this survey.

Results
One hundred eighty-three of the 402 (45.2%) questionnaires were returned. Overall, 4.7% of the respondents asked their female patients regularly about SA; in males, this percentage was 0.6%. Before performing a colonoscopy, these percentages were even smaller (2.4% and 0.6%, respectively). When patients presented with specific complaints, such as chronic abdominal pain or fecal incontinence, 68% of the gastroenterologists asked females about SA and 29% of the males (P &lt; 0.01). The majority of respondents stated it as rather important to receive more training on how to inquire about SA and its implications for treatment.

Conclusion
Gastroenterologists do not routinely inquire about a history of SA and they rarely ask about it before performing colonoscopy. There is a need for training to acquire the skills and knowledge to deal with SA.
Is Oral Sex Really a Dangerous Carcinogen? Let’s Take a Closer Look
Authors: Rosenquist Sara E. 
Published: March 2012

ABSTRACT

Introduction
Questions have recently arisen in the popular press about the association between specific sexual behaviors, namely, fellatio and cunnilingus, with head and neck cancers. Although there has been an overall decline in the incidence of head and neck cancers over the past 25 years, there has been a shift in the distribution of these cancers toward a particular type known as oral squamous cell carcinomas (OSCCs), and a younger demographic. These particular cancers, OSCCs, have been shown to be associated with the human papillomavirus (HPV). Several researchers have suggested that this shift in the epidemiology of head and neck cancers might be attributable to changing sexual practices. While this speculation has caught on in the popular press, there are several interesting contradictions in the existing evidence that suggest this conclusion might be premature and overreached.

Aim
The intent of this article is to help clarify the issues so that sexual medicine professionals can give accurate and up-to-date information to their patients.

Main Outcome Measures
This is a review article; no outcome data are reported. This is a review article; no measures were collected.

Methods
Pubmed search on HPV, oral sex, oral cancers, and OSCCs.

Results
One hundred ninety-six articles on HPV were found; 63 articles on oral sex, 55 on oral cancer, and 5 articles on OSCCs were identified as relevant.

Conclusions
HPV infections occur commonly and are usually cleared within 18 months, thus HPV infection should not be a cause for concern among monogamous couples with a rich and varied sex life as long as the sexual system remains closed and other immune compromising factors are not present. HPV becomes a concern in the context of immune system compromise and infection persistence. Factors contributing to immune system compromise, HPV persistence, and oncogenesis are reviewed.
Discovery of a novel HLA‐B*51 variant, B*51:112, in a Taiwanese bone marrow donor and identification of the plausible HLA haplotype in association with B*51:112
Authors: Yang K. L. , Lee S. K. , Lin P. Y. 
Published: March 2012

SummaryThe sequence of B*51:112 is identical to the sequence of B*51:01:01 in exons 2, 3 and 4, except the nucleotides at positions 206 (C→A) and 213 (C→G). The nucleotide replacement caused one amino acid substitution at residue 45 (T→K). The plausible HLA‐A, ‐B and ‐DRB1 haplotype in association with B*51:112 may be deduced as HLA‐A*02‐B*51:112‐DRB1*12. The generation of B*51:112 was probably as the result of a DNA recombination event where B*40:01:01 acted as a sequence donor donating a segment of the DNA sequence to the recipient sequence B*51:01:01. The donor carrying B*51:112 was a Minna Taiwanese whose ancestor came to Taiwan from the southern region of China.
Towards an effective asteroseismology of solar-like stars: time-dependent convection effects on pulsation frequencies
Authors: Grigahcène A. , Dupret M.-A. , Sousa S. G. , Monteiro M. J. P. F. G. , Garrido R. , Scuflaire R. , Gabriel M. 
Published: March 2012

Abstract
Since the early days of helioseismology, adiabatic models have shown their limits for a precise fitting of individual oscillation frequencies. This discrepancy, which also exists for solar-type stars, is known to originate near the surface superadiabatic convective region where the interaction between oscillations and convection is likely to have a large effect on the frequencies. We present an asteroseismic study to address the adequacy of time-dependent convection (TDC) non-adiabatic models to better reproduce the observed individual frequencies. We select, for this purpose, three solar-like stars, in addition to the Sun, to which we fit the observed frequencies in a grid of TDC non-adiabatic models. The best model selection is done by applying a maximum likelihood method. The results are compared to pure adiabatic and near-surface corrected adiabatic models. We show that, first, TDC models give very good agreement for the mode frequencies and average lifetimes. In the solar case, the frequency discrepancy is reduced to &lt;1.75 µHz over 95 per cent of the modes considered. Secondly, TDC models give an asteroseismic insight into the usually unconstrained ad hoc stellar parameters, such as the mixing-length parameter αMLT.
Fast evolving size of early-type galaxies at z &gt; 2 and the role of dissipationless (dry) merging
Authors: Cimatti A. , Nipoti C. , Cassata P. 
Published: March 2012

Abstract
We present the analysis of a large sample of early-type galaxies (ETGs) at 0 &lt; z &lt; 3 aimed at tracing the cosmic evolution of their size and compare it with a model of pure dissipationless (dry) merging in the Λ cold dark matter (ΛCDM) framework. The effective radius Re depends on stellar mass as with α∼ 0.5 at all redshifts. The redshift evolution of the mass- or SDSS-normalized size can be reproduced as ∝(1 +z)β with β∼−1, with the most massive ETGs possibly showing the fastest evolutionary rate (β∼−1.4). This size evolution slows down significantly to β∼−0.6 if the ETGs at z &gt; 2 are removed from the sample, suggesting an accelerated increase of the typical sizes at z &gt; 2, especially for the ETGs with the largest masses. A pure dry merging ΛCDM model is marginally consistent with the average size evolution at 0 &lt; z &lt; 1.7, but predicts descendants too compact for z &gt; 2 progenitor ETGs. This opens the crucial question on what physical mechanism can explain the accelerated evolution at z &gt; 2, or whether an unclear observational bias is partly responsible for that.
Cross-correlation of WISE galaxies with the cosmic microwave background
Authors: Goto Tomotsugu , Szapudi István , Granett Benjamin R. 
Published: March 2012

Abstract
We estimated the cross-power spectra of a galaxy sample from the Wide-field Infrared Survey Explorer (WISE) survey with the 7-year Wilkinson Microwave Anisotropy Probe (WMAP) temperature anisotropy maps. A conservatively selected galaxy sample covers ∼13 000 deg2 with a median redshift of z= 0.15. Cross-power spectra show correlations between the two data sets with no discernible dependence on the WMAPQ, V and W frequency bands. We interpret these results in terms of the integrated Sachs—Wolfe (ISW) effect: for the |b| &gt; 20° sample at l= 6–87, we measure the amplitude (normalized to be 1 for vanilla Λ cold dark matter expectation) of the signal to be 3.4 ± 1.1, i.e. 3.1σ detection. We discuss other possibilities, but at face value the detection of the linear ISW effect in a flat universe is caused by large-scale decaying potentials, a sign of accelerated expansion driven by dark energy.