bluuebunny/crossref_metadata_2025_split huggingface dataset:
The curvilinear relationships between perceived development human resource practices and both affective commitment and work stress: the moderating effects of age
Authors: Yue Lin-yang , Huang Wei-de 
Published: May 2024

PurposeThis paper aims to reveal the curvilinear relationships between perceived development human resource practices (DHRPs) and both affective commitment and work stress, and the moderating effects of age on the curvilinear relationships.Design/methodology/approachHypotheses were developed from an employee-oriented contingent view based on the person-job fit theory and lifespan development theories. Methods suggested by Haans et al. (2016) and Dawson (2014) to test curvilinear relationships and related moderations, and a two-wave survey data from 742 Chinese employees were used.FindingsThe results showed that perceived DHRPs related to affective commitment in an inverted U shape and work stress in a U shape. However, age moderated the nature of the relationships such that both the curvilinear relationships only existed under low age while under high age perceived DHRPs related to affective commitment positively and work stress negatively.Originality/valueThis study advances the prevailing linear (positive or negative) thinking on the DHRPs–outcomes relationships by showing that perceived DHRPs relate to both affective commitment and work stress nonlinearly. Moreover, different from existing findings that age moderates the strength of the linear DHRPs–outcomes relationships, the results indicate that age moderates the nature of the relationships between perceived DHRPs and affective commitment and work stress. This implies a refined age-differential approach to use DHRPs to sustain a committed and healthy workforce in the context of workforce aging.
Novel nano magnesium oxide modified hybrid emulsion for antimicrobial coating
Authors: Jana Tirthankar , Dhar Tapan Kumar 
Published: May 2024

Purpose
The purpose of this paper is to develop an inorganic-organic hybrid emulsion polymer using grafted hyperbranched alkyd modified with nanometal oxide and to study the performance of the developed hybrid emulsion in paint formulation with respect to antimicrobial and other properties.

Design/methodology/approach
A novel hybrid emulsion polymer was synthesized by grafting of vinyl acetate (VAM), vinyl ester of versatic acid (VeoVa 10) monomers onto hyperbranched alkyd resin and incorporation of nano magnesium oxide (MgO) into the hybrid resin matrix during dispersion of resin in water. Subsequently, paint was prepared by using this hybrid emulsion followed by a performance study.

Findings
The performance of nano MgO modified into VAM and VeoVa 10 grafted hyperbranched alkyd resulted in unique properties of coating especially antimicrobial activity.

Research limitations/implications
In the present study, soya fatty acid, polyol and di basic acid have been used to prepare hyperbranched alkyd by condensation polymerization. Monomers like VAM and VeoVa 10 used for grafting onto hyperbranched alkyd and nano MgO have been incorporated into hybrid resin matrix during emulsification of hybrid resin in water.

Practical implications
Grafting of VAM and VeoVa 10 onto hyperbranched alkyd along with in situ incorporation of nano MgO in resin matrix is an effective technique to achieve excellent coating properties.

Originality/value
Nano MgO modified VAM and VeoVa 10 grafted hyperbranched alkyd-based hybrid emulsion can be used as binder in water-based metal primer, direct to metal (DTM) coating as well as topcoat application. The developed system has antimicrobial properties as well as superior mechanical properties.
Estimation of the public debt threshold effects on economic growth in sub‐Saharan African countries
Authors: Kitutila W. Yannick 
Published: May 2024

AbstractUsing data for 22 sub‐Saharan African (SSA) countries, this paper investigates the effects of public debt on economic growth in SSA countries covering the period 1990–2021. Relying upon the estimation of Panel Smooth Transition Regression and generalized method of moments method, our findings offer strong evidence that public debt nonlinearly impacts economic growth. More specifically, there exists a threshold beyond which public debt exerts a negative effect on growth. These results can be used to formulate economic recommendations that the public authorities could implement to improve public debt management and maintain stable economic growth.
The Puzzle of UK (Under‐) Investment: Is Investment Short‐Termism Just a Supply‐Side Problem in Capital Markets?
Authors: Cowling Marc , Wilson Nicholas 
Published: May 2024

AbstractInvestors and financial market intermediaries have been blamed for under‐investment, low growth and low rates of innovation in the UK, with their behaviour being attributed to short‐termism. Various reasons for short‐termism have been identified, including undervaluing long‐term earnings, increased financial obstacles associated with longer investment horizons, and the adoption of financial control systems to meet investors’ demands for quarterly earnings reports. As a result, firms may opt for suboptimal short‐term investment projects while neglecting potentially valuable long‐term initiatives. Most research has focused on large corporates, which constitute a small fraction of the economy and involve multiple stakeholders. There is a significant knowledge gap regarding small owner‐managed firms that rely primarily on internal financing and bank debt for investment. Our study fills this gap by analysing a comprehensive UK finance and investment decision‐making survey of 1501 firms across all classes. The survey reveals that investment appraisal relies on a ‘payback’ period. We find that 58.8% of firms choose a payback period of 3 years or less, with shorter payback periods more prominent among the smallest firms. This suggests that financial frictions impact the investment behaviour of the smallest firms, while shareholder‐driven short‐termism influences the largest firms but only in relation to research and development projects.
Intratumoral metabolic heterogeneity by 18F‐FDG PET/CT to predict prognosis for patients with thymic epithelial tumors
Authors: Chao Fangfang , Wang Ran , Han Xingmin , Huang Wenpeng , Wang Ruihua , Yu Yanxia , Lin Xuyang , Yuan Ping , Yang Meng , Gao Jianbo 
Published: May 2024

AbstractBackgroundThe aim of the present study was to evaluate the impact of intratumoral metabolic heterogeneity and quantitative 18F‐FDG PET/CT imaging parameters in predicting patient outcomes in thymic epithelial tumors (TETs).MethodsThis retrospective study included 100 patients diagnosed with TETs who underwent pretreatment 18F‐FDG PET/CT. The maximum and mean standardized uptake values (SUVmax and SUVmean), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) on PET/CT were measured. Heterogeneity index‐1 (HI‐1; standard deviation [SD] divided by SUVmean) and heterogeneity index‐2 (HI‐2; linear regression slopes of the MTV according with different SUV thresholds), were evaluated as heterogeneity indices. Associations between these parameters and patient survival outcomes were analyzed.ResultsThe univariate analysis showed that Masaoka stage, TNM stage, WHO classification, SUVmax, SUVmean, TLG, and HI‐1 were significant prognostic factors for progression‐free survival (PFS), while MTV, HI‐2, age, gender, presence of myasthenia gravis, and maximum tumor diameter were not. Subsequently, multivariate analyses showed that HI‐1 (p < 0.001) and TNM stage (p = 0.002) were independent prognostic factors for PFS. For the overall survival analysis, TNM stage, WHO classification, SUVmax, and HI‐1 were significant prognostic factors in the univariate analysis, while TNM stage remained an independent prognostic factor in multivariate analyses (p = 0.024). The Kaplan Meier survival analyses showed worse prognoses for patients with TNM stages III and IV and HI‐1 ≥ 0.16 compared to those with stages I and II and HI‐1 < 0.16 (log‐rank p < 0.001).ConclusionHI‐1 and TNM stage were independent prognostic factors for progression‐free survival in TETs. HI‐1 generated from baseline 18F‐FDG PET/CT might be promising to identify patients with poor prognosis.
The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration
Authors: Iqbal Mohamed Ariff , Bilen Maria , Liu Yubing , Jabre Vanessa , Fong Bensun C. , Chakroun Imane , Paul Smitha , Chen Jingwei , Wade Steven , Kanaan Michel , Harper Mary‐Ellen , Khacho Mireille , Slack Ruth S. 
Published: May 2024

AbstractImpaired mitochondrial function is a hallmark of aging and a major contributor to neurodegenerative diseases. We have shown that disrupted mitochondrial dynamics typically found in aging alters the fate of neural stem cells (NSCs) leading to impairments in learning and memory. At present, little is known regarding the mechanisms by which neural stem and progenitor cells survive and adapt to mitochondrial dysfunction. Using Opa1‐inducible knockout as a model of aging and neurodegeneration, we identify a decline in neurogenesis due to impaired stem cell activation and progenitor proliferation, which can be rescued by the mitigation of oxidative stress through hypoxia. Through sc‐RNA‐seq, we identify the ATF4 pathway as a critical mechanism underlying cellular adaptation to metabolic stress. ATF4 knockdown in Opa1‐deficient NSCs accelerates cell death, while the increased expression of ATF4 enhances proliferation and survival. Using a Slc7a11 mutant, an ATF4 target, we show that ATF4‐mediated glutathione production plays a critical role in maintaining NSC survival and function under stress conditions. Together, we show that the activation of the integrated stress response (ISR) pathway enables NSCs to adapt to metabolic stress due to mitochondrial dysfunction and metabolic stress and may serve as a therapeutic target to enhance NSC survival and function in aging and neurodegeneration.
Can artificial intelligence be integrated into pest monitoring schemes to help achieve sustainable agriculture? An entomological, management and computational perspective
Authors: Leybourne Daniel J. , Musa Nasamu , Yang Po 
Published: May 2024

Abstract
Recent years have seen significant advances in artificial intelligence (AI) technology. This advancement has enabled the development of decision support systems that support farmers with herbivorous pest identification and pest monitoring.
In these systems, the AI supports farmers through the detection, classification and quantification of herbivorous pests. However, many of the systems under development fall short of meeting the demands of the end user, with these shortfalls acting as obstacles that impede the integration of these systems into integrated pest management (IPM) practices.
There are four common obstacles that restrict the uptake of these AI‐driven decision support systems. Namely: AI technology effectiveness, functionality under field conditions, the level of computational expertise and power required to use and run the system and system mobility.
We propose four criteria that AI‐driven systems need to meet in order to overcome these challenges: (i) The system should be based on effective and efficient AI; (ii) The system should be adaptable and capable of handling ‘real‐world’ image data collected from the field; (iii) Systems should be user‐friendly, device‐driven and low‐cost; (iv) Systems should be mobile and deployable under multiple weather and climate conditions.
Systems that meet these criteria are likely to represent innovative and transformative systems that successfully integrate AI technology with IPM principles into tools that can support farmers.
Ancient and historical cooking pots and food: an eternal communion. A topical review
Authors: Heimann Robert B. 
Published: May 2024

AbstractThis contribution provides a topical view at and review of traditional clay‐based utilitarian cooking pots that were used for millennia to prepare, serve, display, and distribute foodstuff. Key mechanical and thermal properties of ceramic cooking vessels will be discussed and strategies of property optimization outlined. In addition, some important chemical changes food constituents undergo during cooking will be explained. Mass‐produced ancient ceramic cooking pots from Neolithic Mesopotamia have revolutionized the art of cooking by allowing foodstuff to be processed in water. As an example of successfully optimizing the properties of cooking vessels, emphasis is being given to Indigenous prehistoric North American ware of the Mississippian culture (c. 800 to 1600 CE) that show impressively how ancient potters overcame the technological challenges posed by essentially unsuitable smectite‐rich clays with extreme plasticity and high swell–shrink ratio by adding copious amounts of burnt mussel shells as temper material.
Seeing disability in children's made for television programmes: An Australian case study
Authors: Carmel Julie‐Mary , Chapman Sian , Wright Peter 
Published: May 2024

AbstractDisability awareness is an issue that can inform societal understanding of marginalised groups. Contemporary literature continues to show the importance of inclusion in society and the impact inclusion has on people with disabilities and society more broadly. The importance of disability awareness is important in the context of the daily challenges faced such as discriminatory practices, stigma, stereotyping and exclusion and manifested in areas such as access to buildings, educational opportunities, and visibility in the media. Given the importance of disability awareness and the significant influence of media, especially on children today, this research investigated the inclusion of disability as one element of ‘awareness’ in one ‘made‐for‐children’ (2–5 years old) television programme. Drawing on a social model of disability, three key concepts of Diversity, Inclusion, and Equity were used to explore the way that disability is portrayed for early learners. Analysis of 265 episodes (2015–2021) revealed that inclusion of disability appeared in fewer than 15% of episodes and was not representative of the community broadly speaking. This lack of representation exposed the limited potential that the media currently has as an educative function for preschool children in disability awareness and understanding of disability as part of contemporary society. Including more people with disabilities in made‐for‐preschool children's programmes is one way to both build awareness and progressively ameliorate this position.
Utility of next‐generation sequencing in the diagnosis of metastatic melanoma: A case report
Authors: Turcios Escobar Saul , Yang Richard , Nelson Kelly C. , Gershenwald Jeffrey E. , Tawbi Hussein , Aung Phyu P. , Patel Sapna P. , Torres‐Cabala Carlos A. 
Published: May 2024

AbstractDuring routine dermatologic examination, a 77‐year‐old male was noted to have a firm blue subcutaneous nodule on his right lateral upper back. His past medical history included metastatic melanoma of unknown primary involving right and left axillary lymph nodes, treated with ipilimumab/nivolumab with complete response, and subsequent primary uveal melanoma. The subcutaneous nodule was located near his previous right axillary scar for metastatic melanoma. Excision of the nodule showed a plexiform neoplasm involving mid and deep dermis composed of spindle and epithelioid atypical cells admixed with numerous melanophages. Central necrosis was present. Immunohistochemical studies revealed the tumor cells to be diffusely positive for HMB45, with retained expression of BAP1 and p16. The tumor cells were negative for PRAME, nuclear expression of β‐catenin, LEF1, and BRAF V600E. Molecular studies demonstrated BAP1 and GNA11 somatic mutations, a profile different from that exhibited by his prior melanoma. Collectively, these data were interpreted as a metastasis from uveal melanoma and not a recurrence of his metastatic likely cutaneous melanoma after complete response to immunotherapy. This case emphasizes the importance of molecular studies for definitive diagnosis in challenging clinical situations, especially when there is discordance among histopathological, immunohistochemical, and molecular studies. Integration of clinical, histopathological, and molecular features is warranted.
Will the State‐owned Capital Transfer Policy Enhance the Sustainability of the Urban Employee Basic Pension Insurance Fund in China?
Authors: Wang Jia , Liu Huan , Li Mei , Li Han 
Published: May 2024

AbstractTo analyze the effect of the state‐owned capital transfer policy on the sustainability of China's urban employee basic pension insurance fund (CUEBPIF), this study develops an actuarial model for pension insurance. The results reveal the following: (i) Without policy intervention, the CUEBPIF would face a deficit in 2027 and a cumulative shortfall of RMB207.44 trillion by 2050, and the proportion of fiscal subsidies for the CUEBPIF in the total fiscal expenditure would increase to 12.86 percent in 2050. (ii) Based on a delayed retirement policy, the transfer of 10 percent of state‐owned capital can delay the onset of the fund deficit by 6 years, and the accumulated shortfall in 2050 would fall to RMB39.42 trillion, and the proportion of fiscal subsidies would decrease by 11.77 percentage points. (iii) The state‐owned capital transfer policy can improve the sustainability of the CUEBPIF and reduce the burden of enterprise social security contributions when the transfer ratio increases to 20 percent.
Does Chinese Environmental Policy Affect Income Inequality? Evidence from the Central Environmental Protection Inspection
Authors: Wei Xiaoyun , Zhao Chuanmin 
Published: May 2024

AbstractThis paper investigates the effect of environmental policy on income inequality. It focuses on the central environmental protection inspection led by the central government in China. Using a difference‐in‐differences approach, it finds evidence that environmental regulation decreased the per capita income and enlarged the gap between urban and rural income while showing an insignificant effect on employment. Although the policy can reduce pollution levels and bring environmental benefits in aggregate, the findings of this study suggest that the regulations appear to have reduced the proportion of manufacturing industry and hindered general innovation and investment from entrepreneurs, which resulted in greater inequality. Rural residents suffered more from environmental regulation due to relatively high migration costs and their disadvantaged human resources on the aspects of health, education level, and skills. The local government's execution incentive can also play a key role in the effectiveness of environmental policy. Regions with lower GDP growth targets and younger government leaders were affected significantly with regard to the income growth of local residents and the urban–rural income gap.
Co‐occurrence of glial fibrillary acidic protein astrocytopathy in a patient with Leber's hereditary optic neuropathy due to DNAJC30 mutations
Authors: Giannoccaro Maria Pia , Morelli Luana , Ricciardiello Fortuna , Donadio Vincenzo , Bartiromo Fiorina , Tonon Caterina , Carbonelli Michele , Amore Giulia , Carelli Valerio , Liguori Rocco , La Morgia Chiara 
Published: May 2024

AbstractLeber's hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by visual loss, and rarely associated with extraocular manifestations including multiple sclerosis‐like lesions. The association of LHON and neuromyelitis optica spectrum disorders has rarely been reported. Here is reported a case of glial fibrillary acidic protein astrocytopathy presenting with area postrema syndrome in a patient with previously diagnosed recessive LHON due to mutations in the nuclear gene DNAJC30. This case emphasizes the necessity of extensive investigations for other treatable conditions in patients with LHON and otherwise unexplained extraocular involvement and the possibility that also visual symptoms can respond to immune therapy.
Antibiotic susceptibility pattern of Helicobacter pylori against eight antibiotics: A study from North India
Authors: Arfi Safiya , Sharma Prateek , Kumar Mithun , Mehra Shubham , Das Kunal , Das Rajashree , Setya Ashwini 
Published: May 2024

AbstractBackgroundThe purpose of this analysis is to evaluate the antimicrobial susceptibility of eight drugs effective against Helicobacter pylori (H. pylori) strains and the genetic diversity of H. pylori virulence genes to foresee clinical outcomes in North India.Materials and MethodsFifty‐eight H. pylori strains isolated from patients suffering from various gastrointestinal (GI) diseases were included in the study. MICs of various antibiotics were determined by the agar dilution method. The chi‐squared test and Fisher exact test were used to determine the p‐value, which was considered significant at p‐value ≤ 0.05. RStudio 4.0 was used to for the data visualization.ResultsThe prevalence of drug resistance was found to be: cefixime (CFM) (41.3%), furazolidone (FZD) (34.4%), amoxicillin (AMX) (20.7%), levofloxacin (LVFX) (70.7%), metronidazole (MTZ) (39.6%), tetracycline (TET) (20.7%), clarithromycin (CLA) (17.2%), and rifabutin (RIF) (17.2%). Out of 58 H. pylori strains, 3 were pan susceptible. There were H. pylori strains with single‐drug resistance (21.8%, 12/55), dual resistance (30.9%, 17/55), triple resistance (20%, 11/55), and multidrug resistance (27.3%, 15/55). The resistance rate in MTZ, CLA and RIF were found to be significantly higher in females as compared to males (p = 0.005, p = 0.002, and p = 0.02), respectively. The resistance to TET exhibited significantly higher levels in gastritis compared to GERD, DU, and other disease groups (p = 0.04) respectively.ConclusionTET, AMX, CLA, and RIF were found to be more effective antibiotics against H. pylori infections, whereas more studies are required to provide evidence on increasing resistance rate of LVFX.