bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment experience, frequency of dental visits, and children’s dental fear: a cognitive approach
Authors: Carrillo‐Diaz Maria , Crego Antonio , Armfield Jason M. , Romero‐Maroto Martin 
Published: January 2012

Carrillo‐Diaz M, Crego A, Armfield JM, Romero‐Maroto M. Treatment experience, frequency of dental visits, and children’s dental fear: a cognitive approach. Eur J Oral Sci 2012; 120: 75–81. © 2012 Eur J Oral SciCognitive elements play a key role in dental anxiety. Nevertheless, relatively little is known about how dental treatments and frequency of visits to the dentist are related to dental fear and its cognitive antecedents. This study aimed to explore the relationships between dental visits, past treatment experiences, expectations on the aversiveness/probability of negative dental events, and dental fear in children. The participants were 147 children (60% female; mean age = 12.0 yr) who completed a questionnaire comprising measures of dental treatment‐related experience (attendance, fillings, and extractions), perceived aversiveness and probability of dental events, and dental anxiety. Bivariate correlations and multiple linear regression analyses were used to analyze the data. A higher frequency of dental visits was associated with less dental fear and a decreased belief in the probability of negative events occurring during treatment. The type of treatments received was not directly linked to dental fear. However, having received fillings was significantly associated with the perceived probability of negative dental events, whereas extractions were positively associated with these expectations but negatively associated with the perceived aversiveness of possible dental events. Regular dental visits, as well as dental treatments, can influence, in different ways, cognitive elements associated with dental anxiety in children.
Fracture resistance of maxillary complete dentures subjected to long‐term water immersion
Authors: Takahashi Yutaka , Yoshida Kaneyoshi , Shimizu Hiroshi 
Published: January 2012

doi: 10.1111/j.1741‐2358.2012.00616.xFracture resistance of maxillary complete dentures subjected to long‐term water immersionObjective:  This study investigated the fracture resistance of maxillary acrylic resin complete dentures subjected to long‐term water immersion.Materials and Methods:  Maxillary acrylic resin complete dentures were fabricated from five denture base resins. Half of the dentures were stored in water for 50 h, and the other half were kept in water for 180 days before testing. Ten specimens were fabricated per group. The flexural load at the proportional limit (FL‐PL) of the dentures was tested.Results:  A two‐way anova revealed a significant difference in FL‐PL because of the denture base material variable. There were no significant differences in FL‐PL because of the effect of water immersion and the interaction between the effect of water immersion and the denture base material. The FL‐PLs of the dentures fabricated with the two conventional heat‐processed resins, the pour‐type autopolymerizing resin and the microwave energy‐processed resin were not significantly different from each other; they were significantly higher than the light‐activated resin in regard to their FL‐PL.Conclusion:  The FL‐PLs of the maxillary acrylic resin complete dentures did not change after long‐tern water immersion, and the FL‐PL of the denture fabricated from the light‐activated resin was lower than those of the other materials.
Translating the Use of An Enriched Environment Poststroke from Bench to Bedside: Study Design and Protocol Used to Test the Feasibility of Environmental Enrichment on Stroke Patients in Rehabilitation
Authors: Janssen H. , Ada L. , Karayanidis F. , Drysdale K. , McElduff P. , Pollack M. , White J. , Nilsson M. , Bernhardt J. , Spratt N. J. 
Published: January 2012

Rationale Environmental enrichment, a paradigm investigated extensively in animal models, is an intervention, which by design facilitates motor, sensory, social, and cognitive activity. It has been shown to improve poststroke motor and cognitive function in animal models of stroke. This is the first study to attempt to translate this intervention from the laboratory to the clinical setting. Aims The overall aim of this pilot study is to test the feasibility of using environmental enrichment with stroke patients in a rehabilitation setting. The aim is to enrich the environment of stroke survivors in a rehabilitation ward and measure changes in their activity (physical, cognitive, and social activity). Design Prospective nonrandomized block design intervention study. Study In the control phase we will determine the change in activity levels of patients treated in a usual rehabilitation environment over time. In the intervention phase structured observational techniques (behavioural mapping) will be used to quantify the change in activity levels of patients exposed to environmental enrichment. Outcomes The primary outcome is change in activity level. Additional data collected on entry to and exit from the study will include: cognitive function using a battery of cognitive tests, general function using the Functional Independence Measure, mood using the Patient Health Questionnaire 9 and boredom using the Stroke Rehabilitation Boredom Survey. Quality of life will be assessed using the Assessment of Quality of Life 1 month postdischarge from rehabilitation. Australian New Zealand Clinical Trials Registry#*** ACTRN12611000629932.
Development of Soy‐Based Bread with Acceptable Sensory Properties
Authors: Ivanovski B. , Seetharaman K. , Duizer L.M. 
Published: January 2012

Abstract:  Consumption of soy protein has been associated with benefits related to numerous areas of health. Due to the widespread consumption of bread, one means of contributing to the health of individuals is through the incorporation of soy protein into bread. To this end, soy flour (SF) or soy protein isolates (SPIs) in 20% and 12% substitution levels, respectively, were added to flour during bread manufacture. The developed breads were tested using a consumer panel for acceptability, using a refined white bread as a control. These data were compared to attribute intensity data collected by the trained panel to identify specific flavor and texture characteristics affecting liking. The sensory profile of the 20% SF bread was acceptable and comparable to the control bread, despite a significantly stronger beany flavor. No significant differences in sensory properties of the SF and control breads were detected by the trained panel for many sensory attributes. The SPI bread, however, had a sensory profile that was significantly more firm, dense, sour, beany, bitter, and astringent with a strong aftertaste in comparison to the wheat control bread. Consumer liking scores for the SPI bread was significantly lower than the liking of the control and the SF added bread.Practical Application:  Many soy‐enriched foods, while contributing positively to health, are considered unacceptable by consumers. This is due to negative sensory properties, such as beany, painty, and astringent notes, often perceived by consumers. This study provides information on the level of SF that can be included in bread in an amount that does not detract from consumer acceptability. This level also allows for a Food and Drug Administration (FDA) health claim to be made.
THE DAWN OF A NEW IDENTITY: ASPECTS OF A RELATIONAL APPROACH TO PSYCHOTHERAPY WITH A TRANSSEXUAL CLIENT
Authors: King Angela 
Published: January 2012

abstractThe importance of developing a certain consciousness in which one is present and autonomous while being intimately interconnected with larger meaning is an important dimension of a relational approach to psychotherapy. Based on the premise that both client and therapist bring something of themselves and of their respective past emotional experience to the therapeutic relationship, a relational approach to therapy is very attentive to the dynamics in the therapy room. It stresses the co‐creation of the therapeutic relationship at conscious, explicit verbal levels and unconscious, implicit levels of functioning, and establishes the therapist's emotional behaviour as a significant factor in fostering change (Aron, 1996).Therapist responsiveness to client's affective impact is discussed with emphasis on its centrality to clinical practice and its relationship to countertransference. A case study of the psychotherapeutic journey with ‘Dawn’ (previously ‘David’), a 53 year‐old client who was awaiting sex‐reassignment surgery, is presented which illustrates how the therapist's struggle in the countertransference represents part of a complex relational body/mind system of parallel processes, re‐enactment and potential for therapeutic change.
A LOOK AT NARCISSISM THROUGH PROFESSOR HIGGINS IN PYGMALION
Authors: Plant David 
Published: January 2012

abstractDrawing upon Professor Higgins in George Bernard Shaw's Pygmalion as a template, and making use of clinical material, I will reflect upon the painful, poignant and self‐inflicted inner loneliness of the narcissistic individual. In order to master early trauma, the narcissistic person constructs an outwardly substantial self in which he seeks to control others and the way he is perceived by others. In so doing he renounces the more emotionally vulnerable parts of himself, the very parts he needs in order to develop a more authentic self and emotionally connect with others. Sometimes a crack appears in his defensive narcissistic structure with the possibility of something more life‐enhancing emerging.
Canine intravascular lymphoma with overt leukemia
Authors: Lane Laura V. , Allison Robin W. , Rizzi Theresa R. , Stern Adam W. , Snider Timothy A. , Moore Peter F. , Vernau William 
Published: January 2012

Abstract:A 6‐year‐old spayedLabradorRetrieverMix dog was evaluated for a 2‐week history of progressive generalized weakness and reluctance to stand. Physical examination revealed severe weakness with obtunded mentation, head tilt, bilateral nystagmus, and decreased vision.CBCfindings included mild nonregenerative anemia, marked thrombocytopenia, and a few atypical mononuclear cells on the blood film. The cells were 15–30 μm in diameter and had round to oval to reniform centrally placed nuclei with stippled chromatin, prominent nucleoli, and abundant basophilic cytoplasm with numerous discrete vacuoles and, occasionally, small azurophilic granules. Similar cells were found in bone marrow. On histologic examination of tissues collected at necropsy, neoplastic cells were detected in bone marrow, hepatic sinusoids, cerebral and meningeal vessels, and in capillaries of the heart, renal interstitium, small intestinal submucosa, and muscularis, and alveolar septa. A small discrete mass in the right atrium consisted of similar neoplastic cells, and the spleen was diffusely infiltrated. Tissue distribution was suggestive of intravascular lymphoma. Neoplastic cells in tissue sections were immunoreactive for vimentin,CD18,CD45, and granzymeBand lacked immunoreactivity for cytokeratin. Neoplastic cells on bone marrow aspirate smears and blood films lacked immunoreactivity forCD3,CD79a,CD1c,CD11b,CD11c,CD11d, andE‐cadherin. In the absence of immunophenotypic evidence for the neoplastic cells being derived fromB‐cell,T‐cell, or histocytic/dendritic lineages and the lack of clonal antigen receptor gene rearrangement(s), along with positive immunoreactivity for granzymeB, a tumor ofNKcells was considered likely. Based on current knowledge, this is the first report of canine intravascular lymphoma, of probableNKcell origin, with peripheral blood involvement.
Engaging Study Abroad Students in Intercultural Learning Through Blogging and Ethnographic Interviews
Authors: Lee Lina 
Published: January 2012

AbstractThe study involved 16 American undergraduate students who used weekly blogs and conducted ethnographic interviews with native speakers to develop their intercultural competence over the course of one semester abroad. Selected blog entries, post‐surveys, and final interviews were collected and analyzed to report the findings. The results show that blog tasks afforded additional opportunities for students to refl ect upon cross‐cultural issues and exchange cultural perspectives with native informants. Blog entries indicate that students demonstrated various stages of intercultural competence from understanding cultural differences to demonstrating attitudes of openness and appreciation for the target culture. The study concludes that the accessibility to networking, the option of using the first language (L1) for self‐refl ection, and effective strategies for interpersonal communication are essential to maximize the potential of blogs for intercultural learning.
Subjective well‐being of elderly women: Conceptual differences between cancer patients, women suffering from chronic ailments and healthy women
Authors: Rijken Mieke , Komproe Ivan H. , Ros Wynand J. G. , Winnubst Jacques A. M. , van Heesch Nicolette C. A. 
Published: January 2012

Studies have shown that the mean scores on global subjective well‐being measures of cancer patients do not differ from the mean scores of other patient samples or samples of healthy individuals. These results give rise to speculations about the nature of the concept subjective well‐being. Therefore, we compared the structure of the concept subjective well‐being between three groups of elderly women (cancer patients, women suffering from chronic ailments and healthy women). This was done by examining the relationships between five dimensions of subjective well‐being (perceived physical health, self‐esteem, negative affect, optimism and loneliness) and two measures of global subjective well‐being (affective well‐being and life satisfaction) in each group of women.The results clearly demonstrate the differences in the relative importance of the five dimensions for the global evaluation of well‐being between the three groups. The most notable finding was that perceived physical health appears to be more strongly related to global subjective well‐being, when the objective health status is worse. The unequal relative importance of dimensions of subjective well‐being should be taken into account when comparing the mean scores on subjective well‐being measures between populations with different states of health.
Two outbreaks of neuropathogenic equine herpesvirus type 1 with breed‐dependent clinical signs
Authors: Barbić L. , Lojkić I. , Stevanović V. , Bedeković T. , Starešina V. , Lemo N. , Lojkić M. , Madić J. 
Published: January 2012

Equine herpesvirus type 1 (EHV‐1) is a worldwide spread pathogen of horses. It can cause abortion, respiratory and neurological disease and consequentially significant economic losses in equine industries. During 2009, two outbreaks of EHV‐1 were confirmed in two stud farms in Eastern Croatia. The first outbreak occurred in February following the import of 12 horses from USA, serologically negative to EHV‐1 before transport. Four mares aborted in the late stage of pregnancy and one perinatal death was recorded. Other six mares showed clinical signs of myeloencephalopathy with fatal end in four. One month later, the second EHV‐1 outbreak was confirmed in stud farm about 100 km further with 17 abortions, three perinatal deaths and one mild neurological case. Epidemiological data showed that the disease was probably introduced in the first stud farm during international transport. The second outbreak started with the introduction of clinically healthy stallion from the first stud farm. Molecular characterisation and phylogenetic analysis confirmed that, despite different clinical signs, the identical virus caused both outbreaks. Both horse populations were free from EHV‐1 infection before the outbreak and had not been vaccinated. Significant difference in clinical signs could be explained by different breed‐related risk factors.
Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma
Authors: Erdag Gulsun , Schaefer Jochen T. , Smolkin Mark E. , Deacon Donna H. , Shea Sofia M. , Dengel Lynn T. , Patterson James W. , Slingluff Craig L. 
Published: January 2012

AbstractImmune cells infiltrating the microenvironment of melanoma metastases may either limit or promote tumor progression, but the characteristics that distinguish these effects are obscure. In this study, we systematically evaluated the composition and organization of immune cells that infiltrated melanoma metastases in human patients. Three histologic patterns of immune cell infiltration were identified, designated immunotypes A, B, and C. Immunotype A was characterized by no immune cell infiltrate. Immunotype B was characterized by infiltration of immune cells limited only to regions proximal to intratumoral blood vessels. Immunotype C was characterized by a diffuse immune cell infiltrate throughout a metastatic tumor. These immunotypes represented 29%, 63%, and 8% of metastases with estimated median survival periods of 15, 23, and 130 months, respectively. Notably, from immunotypes A to C, there were increasing proportions of B cells and decreasing proportions of macrophages. Overall, the predominant immune cells were T cells (53%), B cell lineage cells (33%), and macrophages (13%), with natural killer and mature dendritic cells only rarely present. Whereas higher densities of CD8+ T cells correlated best with survival, a higher density of CD45+ leukocytes, T cells, and B cells also correlated with increased survival. Together, our findings reveal striking differences in the immune infiltrate in melanoma metastases in patients, suggesting microenvironmental differences in immune homing receptors and ligands that affect immune cell recruitment. These findings are important, not only by revealing how the immune microenvironment can affect outcomes but also because they reveal characteristics that may help improve individualized therapy for patients with metastatic melanoma. Cancer Res; 72(5); 1070–80. ©2012 AACR.
HDL of Patients with Type 2 Diabetes Mellitus Elevates the Capability of Promoting Breast Cancer Metastasis
Authors: Pan Bing , Ren Hui , He Yubin , Lv Xiaofeng , Ma Yijing , Li Jing , Huang Li , Yu Baoqi , Kong Jian , Niu Chenguang , Zhang Youyi , Sun Wen-bing , Zheng Lemin 
Published: January 2012

Abstract
Purpose: Epidemiologic studies suggested complicated associations between type 2 diabetes mellitus and breast cancer. High-density lipoprotein (HDL) is inversely associated with the risk and mortality of breast cancer. Our study is to determine the different effects of normal and diabetic HDL on breast cancer cell metastasis.
Experimental Design: MDA-MB-231 and MCF7 cells were treated with N-HDL, D-HDL, G-HDL, and Ox-HDL. Cell metastasis potency was examined using a tail-vein injection model, and cell adhesion abilities to human umbilical vein endothelial cells (HUVEC) and extracellular matrix (ECM) were determined in vitro. Integrin expression and protein kinase C (PKC) activity were evaluated, and PKC inhibitor was applied.
Results: D-HDL dramatically promoted cell pulmonary metastasis (103.6% increase at P &lt; 0.001 for MDA-MB-231 with 1 × 105 cell injection; 157.1% increase at P &lt; 0.05 for MCF7 with 4 × 105 cell injection) and hepatic metastasis (18.1-fold increase at P &lt; 0.001 for MCF7 with 4 × 105 cell injection), and stimulated higher TC-HUVECs adhesion (21.9% increase at P &lt; 0.001 for MDA-MB-231; 23.6% increase at P &lt; 0.05 for MCF7) and TC-ECM attachment (59.9% and 47.9% increase, respectively, for MDA-MB-231 and MCF7, both at P &lt; 0.01) compared with N-HDL. D-HDL stimulated higher integrin (β1, β2, β3, and αν) expression on cell surface and induced higher PKC activity. Increased TC-HUVECs and TC-ECM adhesion induced by D-HDL, G-HDL, and Ox-HDL could be inhibited by staurosporine.
Conclusions: Our study showed that glycation and oxidation of HDL in diabetic patients could lead to abnormal actions on breast cancer cell adhesion to HUVECs and ECM, thereby promoting metastasis progression of breast cancer. This will largely draw the attention of HDL-based treatments in the diabetes patients with breast cancer. Clin Cancer Res; 18(5); 1246–56. ©2012 AACR.
Should Women Receive Left Ventricular Assist Device Support?
Authors: Hsich Eileen M. , Naftel David C. , Myers Susan L. , Gorodeski Eiran Z. , Grady Kathleen L. , Schmuhl Darlene , Ulisney Karen L. , Young James B. 
Published: January 2012

Background—
Small studies have reported women to have worse outcomes and more adverse events after implantation of mechanical circulatory support device compared with men. To further evaluate sex differences in outcome, we used the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS).

Methods and Results—

There were 401 women (pulsatile devices=78) and 1535 men (pulsatile devices=402) from 89 institutions who were prospectively enrolled into the INTERMACS database for primary implantation of a left ventricular assist device (LVAD) between June 23, 2006, and March 31, 2010. Extensive preimplantation and outcome data were collected on all patients. With a mean follow-up of 7 months, 67 females (17%) died and 250 males (16%) died. There was no statistically significant sex difference in mortality for either pulsatile-flow (
P
=0.82) or continuous-flow (
P
=0.95) devices in adjusted and unadjusted models. There were also no statistically significant sex differences with time to first infection, bleeding, or device malfunction. However, female sex was associated with an increased hazard of first neurological event (adjusted hazard ratio, 1.44; 95% CI, 1.05–1.96;
P
=0.020).

Conclusions—
There were no significant sex differences in mortality, time to first infection, bleeding, or device malfunction with either pulsatile- or continuous-flow LVADs. However, women had an increased risk of first neurological event. For urgent/emergent mechanical support, the benefit of LVAD support likely outweighs the risk, but it remains less clear for women undergoing elective LVAD implantation.
Buoyancy Arrest and Shelf–Ocean Exchange
Authors: Brink K. H. 
Published: January 2012

Abstract
When steady flow in a stratified ocean passes between the continental slope and open ocean, its ability to cross isobaths is potentially limited by buoyancy arrest. If the bottom Ekman transport vanishes and there are no interior stresses, then steady linear flow on an f plane must be geostrophic and follow isobaths exactly. The influence of arrest on cross-shelf transport is investigated here to establish 1) whether there are substantial penetration asymmetries between cases with upwelling and downwelling in the bottom boundary layer; 2) over what spatial scales, hence in what parameter regime, buoyancy arrest is important; and 3) the effects of depth-dependent interior flow. The problem is approached using scalings and idealized numerical models. The results show that there is little or no asymmetry introduced by bottom boundary layer behavior. Further, if the stratification is weak or moderate, as measured by a slope Burger number s = αN/f (where α is the bottom slope, N is buoyancy frequency, and f is the Coriolis parameter), buoyancy arrest does not exert a strong constraint on cross-isobath exchange.