bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: The Influence of the Polymer Chain on the Catalysis by Variable Valency Metal Complexes
Authors: Artemov A. V. , Vainstein E. F. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: FR901228: Antineoplastic Antibiotic
Authors: Wang Hwa‐Chain R. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Peptide Receptors: Noncovalent Interactions Involving Peptides
Authors: Schneider Hans‐Jorg , Eblinger Frank , Sirish Mallena 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (E)‐Alkene Peptide Bond Isosteres by Cuprate Opening of Vinyl Aziridines
Authors: Henninger Todd C. , Wipf Peter 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis of Labeled Sterols
Authors: Kovganko N. V. , Ananich S. K. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Di‐ and Polyfunctional Organomagnesium Compounds
Authors: Bickelhaupt F. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure, Function and Potential Therapeutic Importance of NMDA‐Receptors. Part 1. Architecture and Modulation of the Receptors
Authors: Stark Holger , Grassmann Sven , Reichert Ulrich 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Innovative Biofilm Treatment Technologies for Water and Wastewater Treatment
Authors: Lazarova Valentina , Manem Jacques 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Strain and Structure of Sterically Congested Triplet Carbenes
Authors: Tomioka Hideo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanistic Features of the Reactions of Organomagnesium Compounds
Authors: Holm Torkil , Crossland Ingolf 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Current Status of the Application of Ionizing Radiation to Environmental Protection. Part 3. Sewage Sludge, Gaseous and Solid Systems
Authors: Pikaev A. K. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Protein Nuclear Magnetic Resonance Spectroscopy in the New Millennium
Authors: Pfuhl M. , Driscoll P. C. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Resolution Selenium Solid State NMR Spectroscopy as a Tool for Structural Studies of Organoselenium Compounds
Authors: Potrzebowski Marek J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spectral and Theoretical Studies on Thione—Thiol Tautomerism of N‐Containing Heterocycles
Authors: Stoyanov Stefan , Stoyanova Tatyana , Akrivos Pericles D. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Weakly Bonding Interactions in Organochalcogen Chemistry
Authors: Vargas‐Baca Ignacio , Chivers Tristram 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient and Facile Routes to Nitrones
Authors: Katritzky Alan R. , Cui Xilin , Long Qiuhe , Yang Baozhen , Wilcox Allan L. , Zhang Yong‐Kang 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Analgesic Activity of Some Side‐Chain Modified Anpirtoline Derivatives.
Authors: Radl Stanislav , Hezky Petr , Proska Jan , Hejnova Lucie , Krejci Ivan 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Suppression of Ethyl Migration in the Synthesis of 2,5‐Anhydro‐1‐amino‐1,4‐dideoxy‐3‐thio‐D‐threo‐pentitol Hydrochloride, a Key Intermediate for Oral THF 1β‐Methylcarbapenems.
Authors: Bitha Panayota , Strohmeyer Timothy W. , Li Zhong , Lin Yang‐I 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: XAFS Spectroscopy of Organometallic Species and Clusters
Authors: Slovokhotov Yuri L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Polycyclic Azines Derived from Pyrazolo[3,4‐b]pyridine.
Authors: El‐Emary T. I. , Hussein A. M. , El‐Kashef H. S. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Coordination Among Se and Te Fluorides
Authors: Seppelt Konrad 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Continuous and Clean One‐Step Synthesis of Nano‐Particulate Ce1‐xZrxO2 Solid Solutions in Near‐Critical Water.
Authors: Cabanas Albertina , Darr Jawwad A. , Lester Edward , Poliakoff Martyn 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diels—Alder Reactions of Masked p‐Benzoquinones.
Authors: de March Pedro , Figueredo Marta , Font Josep , Rodriguez Sonia 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal Catalysis Involving Cleavages of σ‐Bonds Between Group 14 Elements and Characterization of Metal Complexes Relevant to the Catalyst Intermediates
Authors: Tsuji Yasushi , Obora Yasushi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Synthetic Reactions Using Group 11 Metal Compounds as a Catalyst
Authors: Ito Hajime , Hosomi Akira 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phosphinooxazolines — A New Class of Versatile, Modular P,N‐Ligands for Asymmetric Catalysis
Authors: Helmchen Guenter , Pfaltz Andreas 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Aqueous Trimethylamine‐Mediated Baylis—Hillman Reaction.
Authors: Basavaiah Deevi , Krishnamacharyulu Marimganti , Jaganmohan Rao Anumolu 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Endothelin Receptor Binding Activity of Synthetic Analogues of RES‐1149‐2.
Authors: Kraus George A. , Wang Xuemei 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The structure of native G‐actin
Authors: Wang Hui , Robinson Robert C. , Burtnick Leslie D. 
Published: June 2010

AbstractHeat shock proteins act as cytoplasmic chaperones to ensure correct protein folding and prevent protein aggregation. The presence of stoichiometric amounts of one such heat shock protein, Hsp27, in supersaturated solutions of unmodified G‐actin leads to crystallization, in preference to polymerization, of the actin. Hsp27 is not evident in the resulting crystal structure. Thus, for the first time, we present the structure of G‐actin in a form that is devoid of polymerization‐deterring chemical modifications or binding partners, either of which may alter its conformation. The structure contains a calcium ion and ATP within a closed nucleotide‐binding cleft, and the D‐loop is disordered. This native G‐actin structure invites comparison with the current F‐actin model in order to understand the structural implications for actin polymerization. In particular, this analysis suggests a mechanism by which the bound cation coordinates conformational change and ATP‐hydrolysis. © 2010 Wiley‐Liss, Inc.
Control of cortical rigidity by the cytoskeleton: Emerging roles for septins
Authors: Gilden Julia , Krummel Matthew F. 
Published: June 2010

AbstractThe cortex is the outermost region of the cell, comprising all of the elements from the plasma membrane to the cortical actin cytoskeleton that cooperate to maintain the cell's shape and topology. In eukaryotes without cell walls, this cortex governs the contact between their plasma membranes and the environment and thereby influences cell shape, motility, and signaling. It is therefore of considerable interest to understand how cells control their cortices, both globally and with respect to small subdomains. Here we review the current understanding of this control, including the regulation of cell shape by balances of outward hydrostatic pressure and cortical tension. The actomyosin cytoskeleton is the canonical regulator of cortical rigidity and indeed many would consider the cortex to comprise the actin cortex nearly exclusively. However, this actomyosin array is intimately linked to the membrane, for example via ERM and PIP2 proteins. Additionally, the lipid membrane likely undergoes rigidification by other players, such as Bin‐Amphiphysin‐Rvs proteins. Recent data also indicates that the septin cytoskeleton may play a formidable and more direct role in stabilization of membranes, particularly in contexts where cells receive limited external stabilization from their environments. Here, we review how septins may play this role, drawing on their physical form, their ability to directly bind and modify membranes and actomyosin, and their interactions with vesicular machinery. Deficiencies and alterations in the nature of the septin cytoskeleton may thus be relevant in multiple disease settings. © 2010 Wiley‐Liss, Inc.
Modelling Inhalational Anaesthetics Using Bayesian Feature Selection and QSAR Modelling Methods
Authors: Manallack David T. , Burden Frank R. , Winkler David A. 
Published: June 2010

AbstractThe development of robust and predictive QSAR models is highly dependent on the use of molecular descriptors that contain information relevant to the property being modelled. Selection of these relevant features from a large pool of possibilities is difficult to achieve effectively. Modern Bayesian methods provide substantial advantages over conventional feature selection methods for feature selection and QSAR modelling. We illustrate the importance of descriptor choice and the beneficial properties of Bayesian methods to select context‐dependent relevant descriptors and build robust QSAR models, using data on anaesthetics. Our results show the effectiveness of Bayesian feature selection methods in choosing the best descriptors when these are mixed with less informative descriptors. They also demonstrate the efficacy of the Abraham descriptors and identify deficiencies in ParaSurf descriptors for modelling anaesthetic action.
Synthesis and Evaluation of Bis‐Thiazolium Salts as Potential Antimalarial Drugs
Authors: Caldarelli Sergio A. , Duckert Jean‐Frédéric , Wein Sharon , Calas Michèle , Périgaud Christian , Vial Henri , Peyrottes Suzanne 
Published: June 2010

AbstractAn innovative therapeutic approach based on the use of dicationic derivatives was previously designed to inhibit the biosynthesis of phosphatidylcholine in Plasmodium spp. Among these, bis‐thiazolium salts were shown to block proliferation of the malaria parasite at concentrations in the low nanomolar range. However, due to unsuitable molecular properties such as the presence of the two polar heads and flexibility in the linker, these compounds have low oral bioavailability. To characterize the structural requirements of the linker that lead to more rigid analogues with fewer rotatable bonds but which retain antimalarial activity, a new series of compounds incorporating an aryl moiety and eventually oxygen atoms were prepared, and their biological activity was evaluated. Structure–activity relationships suggest that the optimal linker construct is an aromatic group with two n‐butyl chains branched at the para position; two new leads (compounds 39 and 40) were selected for further development.
Discovery of a Class of Diketopiperazines as Antiprion Compounds
Authors: Bolognesi Maria Laura , Ai Tran Hoang Ngoc , Staderini Matteo , Monaco Alessandra , López‐Cobeñas Alberto , Bongarzone Salvatore , Biarnés Xevi , López‐Alvarado Pilar , Cabezas Nieves , Caramelli Maria , Carloni Paolo , Menéndez J. Carlos , Legname Giuseppe 
Published: June 2010

AbstractPrion diseases are fatal neurodegenerative and infectious disorders for which effective pharmacological tools are not yet available. This unmet challenge and the recently proposed interplay between prion diseases and Alzheimer's have led to a more urgent demand for new antiprion agents. Herein, we report the identification of a novel bifunctional diketopiperazine (DKP) derivative 1 d, which exhibits activity in the low micromolar range against prion replication in ScGT1 cells, while showing low cytotoxicity. Supported by properly addressed molecular modeling studies, we hypothesized that a planar conformation is the major determinant for activity in this class of compounds. Moreover, studies aimed at assessing the mechanism‐of‐action at the molecular level showed that 1 d might interact directly with recombinant prion protein (recPrP) to prevent its conversion to the pathogenic misfolded prion protein (PrPSc)‐like form. This investigation suggests that DKP based antiprion compounds can serve as a promising lead scaffold in developing new drugs to combat prion diseases.
Occupational functioning, sickness absence and medication utilization before and after cognitive–behaviour therapy for generalized anxiety disorders
Authors: Linden Michael , Zubrägel Doris , Bär Thomas 
Published: June 2010

AbstractBackground: Cognitive–behaviour therapy (CBT) is efficacious in reducing symptoms of generalized anxiety disorders (GAD). The question is whether it is also efficient, i.e., whether there are also enduring effects with respect to improving utilization of medication and psychotherapy, or occupational functioning and sick leave after the end of treatment.Method: The study was based on 44 outpatients (age 18–65 years; HAM‐A score ≥18; GAD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria as assessed by standardized interview) who were treated with 25 sessions of CBT (treatment by 12 state‐licensed behaviour therapists in office‐based practice; no psychotropic treatment for the duration of the therapy). The rate of medication treatment, occupational functioning and sick leave was assessed for 8 months before and after the end of treatment.Results: In the comparison of the pre‐treatment and post‐treatment periods, 46.5% versus 7.2% of patients used psychotropic medication for at least 4 weeks and had been 3.1 versus 1.1 days on sickness absence per month, respectively. About 70% of patients showed impairment in occupational role performance during the pre‐treatment phase compared with 5% to 20%, depending on the dimension, in the follow‐up period.Conclusions: The data suggest that CBT is not only efficacious in terms of symptom reduction but also efficient in terms of reducing inappropriate medication intake and improving occupational functioning. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Effects of any treatment should not only pertain to the present symptomatology but also to illness behaviour and occupational and social participation.• When patients with GAD are treated with CBT, a reduction in sickness absence and an improvement of occupational functioning can be observed in the post‐treatment period.• After CBT, a reduction of inappropriate medication can be seen.• The data suggest that CBT in GAD patients reduces not only illness symptoms but also improves illness behaviour and role adjustment.