bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rédactions conversationnelles sur papier et sur ordinateur : une étude de cas
Authors: Dejean Charlotte 
Published: January 2012

Très récemment encore, le modèle de l'apprenant seul face à l'ordinateur était dominant car l'ordinateur était considéré avant tout comme un outil favorisant l'individualisation de l'apprentissage. Depuis quelques années, les technologies au service de l'apprentissage sont envisagées comme pouvant faciliter les interactions sociales (enseignant-apprenants et apprenants-apprenants). C'est dans cette perspective que s'est développé, notamment dans le monde anglophone, un domaine de recherche sur les Apprentissages Collaboratifs Assistés par Ordinateur (ACAO). Les situations de travail auxquelles s'intéresse ce domaine sont le travail à deux ou plusieurs face à un même ordinateur et le travail à plusieurs par le biais de l'ordinateur, c'est-à-dire en réseau (local ou Internet). La situation qui fait l'objet de cette étude relève de la première catégorie évoquée ; on s'intéresse en effet aux interactions entre deux apprenants de Français Langue Étrangère (FLE), rédigeant ensemble un texte avec un même ordinateur. Ces apprenants participent donc à ce que l'on appelle une "rédaction conversationnelle" ou une rédaction collaborative.
Caractérisation des interfaces porteuses d'information mises en œuvre dans un environnement informatique d'aide à l'apprentissage de la lecture
Authors: Pélissier Chrysta 
Published: January 2012

Dans cet article, nous souhaitons présenter une caractérisation des interfaces porteuses d'information présentes dans un module de type ressource dédié à l'apprentissage d'un domaine. Le domaine d'application choisi est l'apprentissage de la lecture et plus particulièrement, nous nous intéressons à l'environnement informatique du projet AMICAL (Architecture Multi-agents Compagnon pour l'Apprentissage de la Lecture). Dans cet environnement, sont intégrés plusieurs modules. Parmi eux, le Module Ressource Lexical (MRL) donne la possibilité à l'apprenant d'abord de sélectionner un élément lexical et ensuite de visiter une ou plusieurs interfaces porteuses d'information associée à cet élément. Les interfaces porteuses d'information mises en jeu dans un tel module sont appelées « situations ». Elles se caractérisent d'une part par un objectif et d'autre part par un déroulement. L'objectif correspond à une ou plusieurs connaissances liées au domaine que l'apprenant doit acquérir au cours de son apprentissage et que l'on choisit de mettre en œuvre plus particulièrement dans cette situation. Le déroulement se caractérise par une structure d'évènements composés eux d'une structure de couples (<connaissance du domaine, action>, moyen).
First Principles Study of TiS2/Graphene Heterojunction as Cathode Material for Sodium–Sulfur Batteries
Authors: Long Pan , Zheng Yunxin , Xiao Jianrong , Wang Zhiyong 
Published: February 2025

AbstractRechargeable batteries are an indispensable part of the development of environmental sustainability, high capacity and excellent conductivity are essential for optimal energy storage. Sodium–sulfur (Na─S) batteries are recognized as promising options for stationary energy storage solutions, which can be attributed to their high theoretical energy density and cost advantages. Additionally, 2D XS2@graphene heterojunction is considered an excellent host material for batteries. Using the first‐principles calculations, a novel 2D TiS2/graphene heterojunction have been theoretically investigated as an anchoring material for sodium–sulfur batteries to mitigate the shuttle effect. First, the composite structure is created by depositing a TiS2 layer onto a single layer of graphene retains its inherent metallic character. Furthermore, the calculated results show that the TiS2/graphene heterojunction exhibits adsorption energy of 1.3 eV for long‐chain sodium polysulfides while maintaining its metallic properties, effectively anchoring polysulfides and inhibiting the shuttle effect. Moreover, a low diffusion barrier (0.31 eV) for Na ion diffusion shows that this heterojunction can enhance electrochemical processes. TiS2/graphene heterojunction may be the candidate for ideal anchoring materials in sodium–sulfur batteries.
Afterglow Copper(I) Iodine Cluster Scintillator
Authors: Zhao Ying‐Nan , Yang Qi , Yao Bo‐Han , Cao Ruo‐Yu , Zhang Han , Wei Shi‐Long , Wei Dong‐Hui , Li Kai , Si Yu‐Bing , Zang Shuang‐Quan 
Published: February 2025

AbstractCopper(I) iodine clusters have drawn intense attention due to their advantageous photophysical properties, such as a high luminescence efficiency, large Stokes shift, and tunable luminescence lifetimes. In this work, a copper(I) iodine cluster (Cu2I2‐CH3CN) was synthesized, which exhibits unique afterglow emission, ultrahigh quantum yield (90.1 % in solid state) and aggregation‐induced emission (AIE) behavior. It was found that thermally activated delayed fluorescence (TADF) and long‐lifetime phosphorescence occur simultaneously in Cu2I2‐CH3CN. The unique photoluminescence properties of Cu2I2‐CH3CN were attributed to the large spin‐orbit coupling (SOC) and long‐term rigidity of the crystal. The high quantum efficiency, TADF characteristics, and heavy‐atom composition of Cu2I2‐CH3CN endow it with excellent X‐ray excited luminescence (XEL) properties, making it a promising X‐ray scintillator. A flexible scintillator screen made of Cu2I2‐CH3CN was successfully fabricated and used for X‐ray imaging with a spatial resolution of 23.6 LP mm−1.
Polycyclic Aromatic Hydrocarbons with a Boron‐Doped Zigzag/Armchair Topology: A Boron‐Edging Strategy for Organic Narrowband Emitters
Authors: Tian Xinyu , Fan Zengming , Li Zeyi , Zhang Shitong , Li Zhiqiang , Zhuang Xuming , Wang Yue , Dou Chuandong 
Published: February 2025

AbstractControl over molecular topologies and/or heteroatom doping of polycyclic aromatic hydrocarbons (PAHs) may alter their electronic structures and achieve desirable physical properties. Herein, this work challenges boron‐doping and edge‐transformation of π‐extended PAHs. We successfully synthesized a series of large‐size PAHs featuring a boron‐doped zigzag/armchair edge topology through one‐pot multifold Scholl cyclization reaction. Two of them possess the desired C3‐symmetric and unexpected unsymmetrical C54B3 nanographene frameworks, respectively, thus illustrating triply boron‐edging manipulations of hexa‐peri‐hexabenzocoronene. Detailed studies reveal that such boron‐doped edge topology significantly inhibits their excited‐state molecular vibrations and thereby produces narrowband emission characteristics. The full width at half maximum (FWHM) values of their fluorescence spectra are as small as 12–18 nm, which have never been observed for pristine boron‐doped π‐system and are among the smallest values reported for organic emitters. Their solution‐processed organic light‐emitting diodes (OLEDs) display extremely narrowband electroluminescence, and additionally, the obtained FWHM of only 23 nm represents the narrowest one reported for red OLEDs.
Synthesis of Functional Pectin‐Based Hydrogels via Thiol‐Maleimide Click Reaction for Enhanced Drug Encapsulation and Release
Authors: Alharbi Hussam Y. , Alnoman Rua B. , Aljohani Majed S. , Monier M. 
Published: February 2025

ABSTRACTThis work describes the synthesis and characterization of a novel hydrogel system based on pectin (PT) functionalized with thiol and maleimide groups and cross‐linked by thiol‐maleimide click chemistry. Thiolated PT (PT‐SH) and maleimide‐modified PT (PT‐Ma) hydrogel precursors were synthesized by carbodiimide‐mediated amidation and confirmed by elemental analysis, FTIR, and 1H NMR spectroscopy. The resulting hydrogel exhibited a gelation efficiency of over 80%, swelling degrees ranging from 44% to 80% depending on cross‐linking density, and pH‐sensitive behavior with maximum swelling at pH 8. The hydrogel demonstrated high mechanical stability, with compressive strengths of 20.8–33.2 kPa, increasing with cross‐linking density. As a model drug, ibuprofen was encapsulated with efficiencies of up to 337 mg/g hydrogel and released in a controlled fashion. In vitro release studies showed a slower release in acidic environments, which ranged from 22% to 53% within 6–10 h, and faster release in a slightly alkaline environment, consistent with the swelling profile of the hydrogel. Such properties underline the hydrogel's potential for sustained drug delivery. Pectin hydrogels, upon thiol‐maleimide cross‐linking, are hereby presented to be a strong platform in biomedical applications based on mechanical properties, swelling behavior, and performance in drug delivery.
High‐Temperature‐Resistant Polyimide Films With Enhanced Tg for Improved Performance in Flexible TFT Devices
Authors: He Dan , Chen Teng , Guo Yuanzheng , Li Guanglan , Liu Xi , Li Chuanyong , Yu Yong , Lan Chuanyan 
Published: February 2025

ABSTRACTFlexible display devices based on polyimide (PI) materials have found widespread applications in the display industry. However, the lower glass transition temperature (Tg) of PI Films limits the process temperature of low‐temperature poly silica (LTPS), resulting in numerous defects in the thin film transistor (TFT) devices. In this paper, mABZ (meta‐amine benzimidazole) was introduced into the PI film, increasing the Tg of PI from 457°C to 481°C and reducing the thermal expansion coefficient (CTE) to 1.09 ppm, thereby the annealing temperature of TFT could be increased to 480°C. Through the high‐temperature process of LTPS TFT and the innovative use of PI as a substrate, the mobility (Mob) of the TFT devices increased by 49%. This enhancement also led to a 33% rise in the on‐state current (Ion). Additionally, the hysteresis decreased by 0.6 V, and the change in threshold voltage (delta Vth) during negative bias stress measurements reduced by 0.36 V. The introduction of high‐temperature‐resistant PI helps reduce the internal defects of the TFT device during the annealing process. The novel PI materials and the TFT device's corresponding high‐temperature process will help reduce the image sticking of OLED display panels and improve the display stability.
Antiviral metabolites from Passiflora edulis: An in vitro, phytochemical, and computational studies
Authors: Elmaidomy Abeer H. , Teutsch Michelle , Bodem Jochen , Bedaiwi Ruqaiah I. , Alzubaidi Mubarak A. , Abou‐Zied Hisham A. , Abdelmohsen Usama Ramadan 
Published: February 2025

AbstractYellow fever (YF) is a mosquito‐borne virus with high mortality rates, affecting regions in South America and Africa. Despite the effectiveness of YF vaccines, increased global demand and reports of rare, severe side effects have spurred the search for safer therapeutic alternatives. Current treatments lack specific antiviral drugs approved for YF, underscoring the need for new, effective therapies. This study investigated the potential of Passiflora edulis f. edulis leaf and stem extracts as antiviral agents against the yellow fever virus (YFV). In vitro tests showed that the extracts significantly reduced YFV viral loads by twofold in Huh‐7 cells and 1.5‐fold in Vero‐h‐Slam cells at a concentration of 50 µg/mL, with a smaller reduction at 25 µg/mL and no cytotoxic effects on either cell line. Phytochemical analysis identified a new C‐deoxyhexosyl flavone, luteolin‐8‐(1‐C‐β‐boivinopyranosyl)‐4′1‐O‐β‐d‐glucopyranoside, along with several known compounds. Protein–protein interaction (PPI) network analysis using the STRING database and Cytoscape software revealed key hub genes, including IFNA1, IL7R, CD19, IL2RA, and IFNG, crucial in antiviral defense. Molecular docking studies further evaluated how these compounds interact with the YFV NS2B‐NS3 protease, essential for viral replication. Molecular dynamics (MD) simulations confirmed the stability of these interactions over a 120‐nanosecond period, supporting the compounds’ antiviral potential. This study demonstrates the promise of Passiflora edulis metabolites as a foundation for developing novel YFV therapies by combining computational and experimental insights.
Sustainability Orientation and Innovation Speed: The Moderating Effects of Competitive Intensity and R&D Agility
Authors: Adomako Samuel , Nguyen Nguyen Phong 
Published: February 2025

ABSTRACTThis article explores the contingent factors that shape the relationship between sustainability orientation and innovation speed. Although the body of research on sustainability orientation is growing, a lack of studies focusing on the contextual and boundary conditions affecting sustainability orientation. Additionally, little is known about how sustainability orientation influences innovation speed in emerging markets. To address this, we expand the literature by developing and testing a model that examines the moderating effects of R&D agility and competitive intensity on the link between sustainability orientation and innovation speed. Specifically, we investigate how sustainability orientation affects innovation speed and how R&D and perceptions of competitive intensity moderate this effect. Based on time‐lagged data from 257 manufacturing firms in Vietnam, our findings reveal that sustainability orientation negatively influences firms' innovation speed. The results also reveal that R&D agility attenuates the negative impact of sustainability orientation on innovation speed. Furthermore, we observe that the negative relationship between sustainability orientation and innovation speed is weakened when both R&D agility and competitive intensity are high. Our detailed analysis extends the conceptual reach of sustainability orientation and increases its applicability to non‐Western contexts.
A Unique Case of Fungal Endometritis Caused by Aspergillus quadrilineatus in an Immunocompetent Woman and Literature Review
Authors: Ranjbar Golafshani Fatemeh Zahra , Ghaffari Lashkenari Erfan , Kermani Firoozeh , Abbaszadeh Godarzi Soheila , Mahdavi Omran Saeid 
Published: February 2025

ABSTRACTAbnormal uterine bleeding (AUB) is a common gynecological concern often attributed to hormonal disorders, malignancies, or infections. While bacterial and viral infections are frequently investigated, fungal infections, such as aspergillosis, are often overlooked. This case report highlights a rare instance of endometrial aspergillosis caused by Aspergillus quadrilineatus in an immunocompetent woman. A 64‐year‐old woman presented with persistent vaginal bleeding. Histopathological examination of endometrial tissue revealed septate hyphae consistent with fungal infection. Molecular analysis identified the causative agent as A. quadrilineatus. The A. quadrilineatus isolate demonstrated susceptibility to various antifungal agents, including azoles and amphotericin B. This report emphasizes the need for increased awareness of fungal infections, including aspergillosis, as a potential cause of AUB. Further research is needed to enhance understanding of the epidemiology, risk factors, and clinical manifestations of endometrial aspergillosis.
Relevance and Timing of Implant‐Driven Rehabilitation in Central Giant Cell Granuloma Cases—A Scoping Review
Authors: Tatiana Roman , Thomas Robert , Olivier Leclercq , Gilbert Nafash , Naji Kharouf , Etienne Olivier , Francois Boschin 
Published: February 2025

ABSTRACTObjectivesCentral giant cell granuloma (CGCG) is a rare benign tumor. Extended aggressive lesions require large resections, which can lead to bone defects and tooth loss. Rehabilitative treatment is necessary to restore good aesthetics and function. However, the protocol for implant treatment post‐CGCG is still unclear. The objective of this scoping review is to shed light on the rehabilitation protocol for CGCG sites by outlining the relevance and timing of implant surgery and prosthetic rehabilitation.Materials and methodsThe review followed the Preferred Reporting Items for Systematic Review and Meta‐Analyses statement and searched databases for data published between 1999 and 2023. The scoping review aimed to answer the question: “In patients with a diagnosed and treated CGCG, able to receive an implant, does the CGCG tumor recur before or after implant surgery”? Only articles that described cases where patients with a diagnosed CGCG received an implant in a site previously affected by CGCG were included.ResultsThe review describes seven case reports and one case series that discuss implantology‐driven restoration after CGCG exeresis in humans. The patients, aged between 7 and 80 years, underwent surgical removal of CGCG and received implant‐supported prosthetic rehabilitation. A total of 34 implants were placed between 4 and 60 months after the tumor‐resection surgery. No recurring lesions were observed during the follow‐up period, which ranged between 2 and 12 years.ConclusionsBased on the limited evidence available, it appears that implant placement after CGCG removal is safe after a minimum of 4 months of healing. However, further research is necessary to confirm this conclusion.
Proposal and Evaluation of a Pitch Estimation Model Based on Reconstruction of the Spectrum of Input Sound by Using Timbre Information and Pitch Information
Authors: Kawa Ryoji , Banno Hideki , Asahi Kensaku 
Published: February 2025

ABSTRACTAutomatic music transcription (AMT) is a task that automatically generates music scores from the sound of music. Pitch estimation is one of the most important technologies in AMT, and its accuracy strongly affects the quality of AMT. Although its accuracy is improving, thanks to deep neural networks nowadays, pitch estimation for multi‐instrumental music is still a challenging task, because there are many difficulties caused by numerous and complicated timbre patterns in multi‐instrumental music. In this paper, we propose a pitch estimation model based on the reconstruction of the spectrum of input sound which can reduce the effect of timbre complexity on pitch estimation. The experimental result indicated that the proposed model improved the average precision by 8.8 points compared to the conventional method.
Recent Advances in the Multicomponent Reactions of Indoles
Authors: Zhang Xiaoxiang , Lu Xiaohe , Zhang Pengyan , Dai Maoyi , Liang Taoyuan 
Published: February 2025

AbstractIndoles, which are distinguished by their nitrogen‐containing heterocyclic structure, play a pivotal role in organic chemistry due to their diverse biological profiles and unique chemical reactivity. In particular, poly‐substituted indoles are extensively found in a wide range of natural products, pharmaceuticals, materials, and bioactive compounds. The integration of indoles into multicomponent reactions (MCRs) has emerged as a powerful synthetic strategy, facilitating the construction of these complex poly‐substituted indole frameworks from simple precursors. This review highlights the latest advancements in MCRs involving indoles, focusing on innovative methodologies for site‐selective synthesis of indole derivatives, catalytic systems, mechanistic insights, and their applications. The review encompasses significant developments from 2014 to 2024 and covers a variety of indole MCRs, including those targeting the C3 position, dual‐site reactions at the C2 and C3 positions, and reactions involving the pyrrole and benzene rings of the indole scaffold.
Proarrhythmic Lipid Inflammatory Mediators: Mechanisms in Obesity Arrhythmias
Authors: Bahrami Pegah , Aromolaran Kelly A. , Aromolaran Ademuyiwa S. 
Published: February 2025

ABSTRACTThe prevalence of obesity and associated metabolic disorders such as diabetes is rapidly increasing; therefore, concerns regarding their cardiovascular consequences, including cardiac arrhythmias, are rising. As obesity progresses, the excessively produced lipids accumulate in unconventional areas such as the epicardial adipose tissue (EAT) around the myocardium. Metabolic alterations in obesity contribute to the transformation of these ectopic fat deposits into arrhythmogenic substrates. However, despite advances in therapeutic approaches, particularly in lowering EAT volume and thickness through sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors and glucagon‐like peptide‐1 (GLP‐1) receptor agonists, obese and diabetic patients still suffer from fatal arrhythmias that may lead to sudden cardiac death. Therefore, an investigation into how unappreciated underlying pathways such as lipid mediators contribute to the transformation of adipose tissues into proinflammatory and arrhythmogenic substrates is of significance. Leukotriene B4 (LTB4) is an eicosanoid derived from arachidonic acid and acts as a lipid mediator. LTB4 has recently been identified to be associated with cardiac ion channel modulations and arrhythmogenic conditions in diabetes. LTB4 increases circulatory free fatty acids (FFAs) and has been associated with adipocyte hypertrophy. LTB4 also interferes with insulin signaling pathways, instigating insulin resistance (IR). In addition, LTB4, as a potent chemoattractant, contributes to the mobilization of circulatory immune cells such as monocytes and promotes inflammatory macrophage polarization and macrophage dysfunction. Thus, this review provides a comprehensive overview of LTB4's underlying pathways in obesity; illustrates how these pathways might lead to alterations in cardiac ion channels, currents, and cardiac arrhythmias; and shows how they might pose a therapeutic target for metabolic‐associated arrhythmias.
An integrated communication and technical skills educational intervention in critical healthcare situations: A qualitative method
Authors: Juliá‐Sanchis Rocío , Escribano Silvia , Sánchez‐Marco María , García‐Aracil Noelia , Perpiñá‐Galvañ Juana , Cabañero‐Martínez Maria José 
Published: February 2025

AbstractAimTo evaluate a postgraduate educational intervention that integrates communication and technical skills in critical healthcare situations for interprofessional teams from the perspective of students and lecturers.MethodsIn phase 1, students and lecturers participated in the evaluation of the strengths, weaknesses, opportunities, and threats of the Sim‐IPE educational intervention included in a postgraduate program, generating a list of improvement actions. In phase 2, an expert panel prioritized the items on the list.ResultsBoth groups addressed nearly identical themes, albeit with different points of view, allowing the panellists to have a broad vision of the issue. Students identified six themes: competence acquisition, pre‐briefing, debriefing, fidelity, resources, and teaching team. Lecturers added a seventh theme related to how students systematically emphasize technical skills over communication skills, and the difficulties in balancing interprofessional groups and scenarios with students with varying professional experiences. A list of 23 improvement actions was generated. Panellists prioritized nine action points for improvement and grouped them into three categories (competitiveness of the program, aspects of the pre‐briefing, and aspects of the debriefing).ConclusionsThe program is expected to promote Sim‐IPE intervention through the master's degree website, generate a complete preplanned briefing script, and sensitize students to the relevance of integrating communication skills in critical situations. Academic institutions will achieve quality educational intervention that is updated and aligned with best academic practices and equip students with the skills and knowledge necessary to succeed academically and professionally.Reporting MethodThis research has adhered to relevant EQUATOR guidelines, the consolidated criteria for reporting qualitative studies (COREQ 32‐item checklist).Patient or Public ContributionSixteen participants from a master's degree in emergencies and disasters and seven panellists completed the research.