bluuebunny/crossref_metadata_2025_split huggingface dataset:
The phase discharge and luminescence area characteristics of La0.5Sr0.5CoO3 as a cathode
Authors: Ichibakase Tsuyoshi 
Published: July 2011

AbstractLa0.5Sr0.5CoO3 was used as a cathode for the first time when a plasma display panel was used on a handheld personal computer. It has favorable sputtering resistance characteristics and stable discharge characteristics in gases. A cathode made of La0.5Sr0.5CoO3 has unique electrical characteristics in early phase discharge voltage and luminescence characteristics. The discharge voltage and luminance continue to decrease from the starting value. The discharge and luminescence area shift of the La0.5Sr0.5CoO3 were investigated by analysis of a DC plasma panel fabricated as a prototype. It is assumed that the shift in the discharge voltage and luminance are caused by a shift in the discharge and luminance area of the cathode surface, and that the shift of the current density is caused by the surface profile of the cathode particles. In order to elucidate this mechanism, a spherical model was applied to the discharge voltage shift, and the shift of the discharge voltage and luminance was simulated by applying this model to the measured values. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(8): 12–18, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10353
Contributions of streamflow variability, concentration–discharge shifts and forested wetlands to terrestrial–aquatic solute export in Precambrian Shield headwater catchments
Authors: Richardson Murray C. 
Published: July 2011

ABSTRACTHydrological and biogeochemical processes in terrestrial watershed compartments are an important source of short‐ and long‐term physico‐chemical dynamics in Precambrian Shield headwater lakes. In this study, a residual analysis of concentration discharge models based on the composite method of stream solute flux estimation was conducted to quantify two key factors contributing to terrestrial–aquatic export of sulphate (SO42−), dissolved organic carbon (DOC), hydronium ion (H+) and colour for ten Precambrian Shield catchments in three lake basins: (1) advective transport capacity, as influenced by variations in runoff, and (2) the terrestrial supply of mobilizable solute, as influenced by terrestrial biogeochemical cycling and associated controlling variables. Overall, annual fluxes associated with mechanism (2) were approximately equal to those associated with mechanism (1) in driving inter‐annual deviations from long‐term mean annual solute export. There was considerable variation in the relative contributions of these mechanisms among solutes and watersheds, and % wetland area could not explain these differences. However, mean annual terrestrial‐aquatic fluxes of DOC and colour were highly correlated with % wetland area, as were inter‐annual variations in mean annual flux. The corresponding relationships between H+ and % wetland area were moderate but also significant. Annual fluxes SO42− were negatively associated with wetlands but there was no relationship between inter‐annual variations in mean annual SO42− flux and % wetland area. The contribution of forested wetlands to annual flux variability for DOC, colour and H+ was primarily driven by inter‐annual differences in runoff and associated mobilization of large solute pools within these critical source areas of organic carbon and acidity. Copyright © 2011 John Wiley & Sons, Ltd.
Quaternary Heusler Compounds without Inversion Symmetry: CoFe1+xTi1–xAl and CoMn1+xV1–xAl
Authors: Basit Lubna , Fecher Gerhard H. , Chadov Stanislav , Balke Benjamin , Felser Claudia 
Published: July 2011

AbstractWe report the quaternary Heusler compound derivatives CoFe1+xTi1–xAl and CoMn1+xV1–xAl, which do not have centers of inversion. Classical T2T′M (T, T′ = transition metal, M = main group element) Heusler compounds (prototype: Cu2MnAl) crystallize in the L21 structure, space group Fm$\bar {3}$m (225) that exhibits a center of inversion. Replacing one of the T2 atoms by another transition element (T″) results in a quaternary TT′T″M compound with F$\bar {4}$3m symmetry (Y; structure type LiMgPdSn) without center of inversion. In the case of “quasi closed shell” compounds with 24 valence electrons in the primitive cell, one expects the absence of ferromagnetism according to the Slater–Pauling rule. Increasing the number of valence electrons will allow a study of the onset of the magnetic ground state. In this work, CoFeTiAl and isovalent CoMnVAl as well as the accompanying solid solutions CoFe1+xTi1–xAl and CoMn1+xV1–xAl were synthesized and their structure and magnetic properties investigated. CoMn1+xV1–xAl (x > 0) is a half‐metallic ferrimagnet in which the magnetic ground state is controlled by the strong localized moment at the Mn atoms replacing V.
Recent Exploitation of Luminescent Rhenium(I) Tricarbonyl Polypyridine Complexes as Biomolecular and Cellular Probes
Authors: Lo Kenneth Kam‐Wing , Zhang Kenneth Yin , Li Steve Po‐Yam 
Published: July 2011

AbstractThe interesting emission properties of rhenium(I) tricarbonyl polypyridine complexes have been exploited in the development of various sensors and probes for analytes. Luminescent probes targeting biomolecules have also been developed. Additionally, there has been a fast‐growing interest in the cellular uptake properties of these complexes with a focus on their potential as cellular imaging reagents. In this Microreview, we describe the fundamental emission characteristics of luminescent rhenium(I) tricarbonyl polypyridine complexes and explain why they hold promise for use as luminescent sensors. Additionally, we summarize the recent design of these complexes as biomolecular and cellular probes, with an emphasis on studies of their structure–property relationships, bioconjugation, biomolecular binding, cellular uptake, cytotoxicity, and bioimaging applications.
Chiral Squaramide‐Catalyzed Enantioselective Conjugate Michael Addition of Various Thiols to α,β‐UnsaturatedN‐Acylated Oxazolidin‐2‐ones
Authors: Dai Le , Yang Hongjun , Chen Fener 
Published: July 2011

AbstractA highly enantioselective sulfa‐Michael addition (SMA) of various thiols to α,β‐unsaturatedN‐acylated oxazolidinones has been achieved with a chiral squaramide catalyst under very mild reaction conditions. In addition, the conversion of the β‐thio‐substituted adduct to the corresponding methyl β‐tosylbutanoate was demonstrated in high yield through a methanolysis/oxidation sequence.
Synthesis and [2+2] Cycloaddition with Tetracyanoethylene of Ene–Diyne Scaffolds Bearing Ferrocenes at the Periphery
Authors: Shoji Taku , Ito Shunji , Okujima Tetsuo , Morita Noboru 
Published: July 2011

AbstractThe ene–diyne systems 1 and 2, possessing ferrocenyl groups at the periphery, were prepared by a simple one‐pot Sonogashira–Hagihara coupling reaction of ethynylferrocene with 9‐dibromomethylene‐9H‐fluorene (4) and 9,10‐bis(dibromomethylene)‐9,10‐dihydroanthracene (5). Ene–diyne 1 reacted with tetracyanoethylene (TCNE) in a formal [2+2] cycloaddition reaction, followed by ring opening of the initially formed [2+2] cycloadduct, cyclobutene, to afford the corresponding 1,1,4,4‐tetracyanobutadiene (TCBD) derivative 6 in good yield. The redox behavior of the ene–diyne compounds 1 and 2, and the TCBD derivative 6 was examined by cyclic voltammetry (CV) and differential pulse voltammetry (DPV), which revealed their electrochemical oxidation properties with multi‐electron transfer depending on the number of ferrocene units in the molecule, in addition to the two‐electron reduction of the TCBD moiety in the case of TCBD derivative 6. Moreover, a significant color change was observed by visible spectroscopy under electrochemical oxidation conditions and under reduction conditions in the case of TCBD derivative 6.
Motivational underpinnings of social influence in work settings: Bases of social power and the need for cognitive closure
Authors: Pierro Antonio , Kruglanski Arie W. , Raven Bertram H. 
Published: July 2011

AbstractThis research explored the notion that the use and efficacy of influence tactics launched from different social power bases depends on influence agents' and recipients' need for cognitive closure. In three separate studies conducted in diverse organizational contexts, it was found that, while overall participants exhibited a preference for soft over hard social influence tactics, this preference becomes less pronounced for supervisors high (versus low) on need for closure and becomes more pronounced for supervisors low on the need for closure. Overall, soft tactics were more beneficial for subordinates' performance than hard tactics; however, the benefits of soft tactics decreased as a function of subordinates' need for closure. Finally, organizational outcomes were improved when recipients who were high (versus low) on the need for closure were exposed to “hard” power tactics and those low (versus high) in the need for closure were exposed to “soft” tactics. Copyright © 2011 John Wiley & Sons, Ltd.
Association of Candidate Genes with Phenotypic Traits Relevant to Anorexia Nervosa
Authors: Root Tammy L. , Szatkiewicz Jin P. , Jonassaint Charles R. , Thornton Laura M. , Pinheiro Andrea Poyastro , Strober Michael , Bloss Cinnamon , Berrettini Wade , Schork Nicholas J. , Kaye Walter H. , Bergen Andrew W. , Magistretti Pierre , Brandt Harry , Crawford Steve , Crow Scott , Fichter Manfred M. , Goldman David , Halmi Katherine A. , Johnson Craig , Kaplan Allan S. , Keel Pamela K. , Klump Kelly L. , La Via Maria , Mitchell James E. , Rotondo Alessandro , Treasure Janet , Woodside D. Blake , Bulik Cynthia M. 
Published: July 2011

AbstractThis analysis is a follow‐up to an earlier investigation of 182 genes selected as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN). As those initial case–control results revealed no statistically significant differences in single nucleotide polymorphisms, herein, we investigate alternative phenotypes associated with AN. In 1762 females, using regression analyses, we examined the following: (i) lowest illness‐related attained body mass index; (ii) age at menarche; (iii) drive for thinness; (iv) body dissatisfaction; (v) trait anxiety; (vi) concern over mistakes; and (vii) the anticipatory worry and pessimism versus uninhibited optimism subscale of the harm avoidance scale. After controlling for multiple comparisons, no statistically significant results emerged. Although results must be viewed in the context of limitations of statistical power, the approach illustrates a means of potentially identifying genetic variants conferring susceptibility to AN because less complex phenotypes associated with AN are more proximal to the genotype and may be influenced by fewer genes. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association.
Screening of multiple hormonal activities in surface water and sediment from the Pearl River system, South China, using effect-directed in vitro bioassays
Authors: Zhao Jian-Liang , Ying Guang-Guo , Yang Bin , Liu Shan , Zhou Li-Jun , Chen Zhi-Feng , Lai Hua-Jie 
Published: July 2011

Abstract
This paper reports screening of multiple hormonal activities (estrogenic and androgenic activities, antiestrogenic and antiandrogenic activities) for surface water and sediment from the Pearl River system (Liuxi, Zhujiang, and Shijing rivers) in South China, using in vitro recombinant yeast bioassays. The detection frequencies for estrogenic and antiandrogenic activities were both 100% in surface water and 81 and 93% in sediment, respectively. The levels of estrogenic activity were 0.23 to 324 ng 17β-estradiol equivalent concentration (EEQ)/L in surface water and 0 to 101 ng EEQ/g in sediment. Antiandrogenic activities were in the range of 20.4 to 935 × 103 ng flutamide equivalent concentration (FEQ)/L in surface water and 0 to 154 × 103 ng FEQ/g in sediment. Moreover, estrogenic activity and antiandrogenic activity in sediment showed good correlation (R2 = 0.7187), suggesting that the agonists of estrogen receptor and the antagonists of androgen receptor co-occurred in sediment. The detection frequencies for androgenic and antiestrogenic activities were 41 and 29% in surface water and 61 and 4% in sediment, respectively. The levels of androgenic activities were 0 to 45.4 ng dihydrotestosterone equivalent concentration (DEQ)/L in surface water, and the potency was very weak in the only detected sediment site. The levels of antiestrogenic activity were 0 to 1,296 × 103 ng tamoxifen equivalent concentration (TEQ)/L in surface water and 0 to 89.5 × 103 ng TEQ/g in sediment. The Shijing River displayed higher levels of hormonal activities than the Zhujiang and Liuxi rivers, indicating that the Shijing River had been suffering from heavy contamination with endocrine-disrupting chemicals. The equivalent concentrations of hormonal activities in some sites were greater than the lowest-observed-effect concentrations reported in the literature, suggesting potential adverse effects on aquatic organisms. Environ. Toxicol. Chem. 2011;30:2208–2215. © 2011 SETAC
On the pressure approximation in nonstationary incompressible flow simulations on dynamically varying spatial meshes
Authors: Besier Michael , Wollner Winnifried 
Published: July 2011

SUMMARYThe subject of this paper is a defect in the approximation of the pressure on dynamically changing spatial meshes in the computation of nonstationary incompressible flows. The observed behavior is due to the fact that discrete solenoidal fields lose this property under changes of the spatial discretization. This phenomenon is analyzed for DG finite element discretizations in time, and possible ways are considered to circumvent this problem. Copyright © 2011 John Wiley & Sons, Ltd.
Break Detectability and Mean Square Forecast Error Ratios for Selecting Estimation Windows
Authors: Ahumada Hildegart A. 
Published: July 2011

ABSTRACTIt has been suggested that a major problem for window selection when we estimate models for forecasting is to empirically determine the timing of the break. However, if the window choice between post‐break or full sample is based on mean square forecast error ratios, it is difficult to understand why such a problem arises since break detectability and these ratios seem to have the same determinants. This paper analyses this issue first for the expected values in conditional models and then by Monte Carlo simulations for more general cases. Results show similar behaviour between rejection frequencies and the ratios but only for break tests that do not take into account forecasting error covariances, as is the case with mean square forecast error measures. Moreover, the asymmetric shape of the frequency distribution of the ratios could help us to better grasp empirical problems. An illustration using actual data is given. Copyright © 2011 John Wiley & Sons, Ltd.
THE IMPACT OF VOLUNTARY HEALTH INSURANCE ON HEALTH CARE UTILIZATION AND OUT‐OF‐POCKET PAYMENTS: NEW EVIDENCE FOR VIETNAM
Authors: Nguyen Cuong Viet 
Published: July 2011

SUMMARYVietnam aims to achieve full coverage of health insurance in 2015. An increasing type of health insurance in Vietnam is voluntary health insurance. Although there are many studies on the implementation of voluntary health insurance in Vietnam, little is known on the causal impact of voluntary health insurance. This paper measures the impact of voluntary health insurance on health care utilization and out‐of‐pocket payments using Vietnam Household Living Standard Surveys in 2004 and 2006. It was found out that voluntary health insurance helps the insured people increase the annual outpatient and inpatient visits by around 45% and 70%, respectively. However, the effect of voluntary health insurance on out‐of‐pocket expenses on health care services is not statistically significant. Copyright © 2011 John Wiley & Sons, Ltd.
Upregulation of prostate‐derived Ets factor by luteolin causes inhibition of cell proliferation and cell invasion in prostate carcinoma cells
Authors: Tsui Ke‐Hung , Chung Li‐Chuan , Feng Tsui‐Hsia , Chang Phei‐Lang , Juang Horng‐Heng 
Published: July 2011

AbstractLuteolin is a polyphenolic flavone and has antitumor activity for many cancers. The prostate‐derived Ets factor (PDEF), a novel epithelium‐specific Ets transcription factor, acts as an androgen‐independent transcriptional activator of the prostate‐specific antigen (PSA) promoter. We determined the antitumor function of luteolin via upregulation of PDEF gene expression in human prostate carcinoma LNCaP cells. Results from flow cytometry and 3H‐thymidine incorporation assays revealed that luteolin treatments attenuated cell proliferation and arrested the cell cycle at the G1/S phase. High concentration of luteolin (30 μM) induced cell apoptosis. Immunoblot assays and enzyme linked immunosorbent assay revealed that luteolin treatment upregulated PDEF but downregulated androgen receptor (AR) gene expression, which decreased PSA gene expression in LNCaP cells. Results of immunoblot and transient gene expression assays revealed that luteolin treatments at proapoptosis dosage, enhanced gene expression of PDEF, B‐cell translocation gene 2 (BTG2), N‐myc downstream regulated gene 1 (NDRG1) and Maspin. Transient gene expression assays indicated that cotransfection of the PDEF expression vector enhanced the promoter activities of the BTG2, NDRG1 and Maspin genes. Stable overexpression of PDEF significantly induced BTG2, NDRG1 and Maspin gene expression, which markedly attenuated in vitro cell proliferation and invasion of LNCaP cells. The modulatory effect of luteolin on BTG2, NDRG1 and Maspin gene expression were attenuated when PDEF was knocked‐down. These results suggest that luteolin blocks PSA gene expression by downregulation of AR expression. The enhancement of PDEF expression, which induced BTG2, NDRG1 and Maspin gene expression, could account for the function of luteolin for antiproliferation and anti‐invasion in LNCaP cells.
Use of nonsteroidal anti‐inflammatory drugs and risk of basal cell carcinoma in the United States radiologic technologists study
Authors: Cahoon Elizabeth K. , Rajaraman Preetha , Alexander Bruce H. , Doody Michele M. , Linet Martha S. , Freedman D. Michal 
Published: July 2011

AbstractNonsteroidal anti‐inflammatory drugs (NSAIDs) have been associated with reduced risk of colorectal and other cancers, but the association with basal cell carcinoma (BCC) is unclear. Previous epidemiological studies have been small in size, conducted in especially vulnerable populations, or have not accounted for solar ultraviolet exposure, a major risk factor for BCC. In the United States Radiologic Technologists cohort, we followed subjects to assess NSAID use on risk of first incident BCC. We included Caucasian participants who responded to both second and third questionnaires (administered from 1994 to 1998 and 2003 to 2005, respectively), and who reported no cancer at the time of the second questionnaire, N = 58,213. BCC, constituent risk factors (e.g., eye color, complexion, hair color) and sun exposure history were assessed through self‐administered survey. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Cox proportional hazards models. Of the 58,213 people in the study population, 2,291 went on to develop BCC. Any NSAID use was not associated with subsequent incidence of BCC (HR = 1.04, 95% CI: 0.92–1.16) after adjusting for age, sex and estimated lifetime summer sun exposure. Neither association was observed when stratified by NSAID type (aspirin and other NSAIDs), nor did dose–response patterns emerge by frequency of use (average days per month). Further analyses did not reveal interaction with sex, birth cohort, smoking, alcohol consumption, sun exposure, occupational radiation exposure or personal risk factors for BCC. In this large nationwide study, we observed no association between NSAID use and subsequent BCC risk.
Diagnostic performance of one‐step nucleic acid amplification for intraoperative sentinel node metastasis detection in breast cancer patients
Authors: Le Frère‐Belda Marie‐Aude , Bats Anne‐Sophie , Gillaizeau Florence , Poulet Bruno , Clough Krishna B. , Nos Claude , Peoc'h Michel , Seffert Pierre , Bouteille Catherine , Leroux Agnès , Guillemin François , Blanc‐Fournier Cécile , Crouet Hubert , Arnould Laurent , Cuisenier Jean , Penault‐Llorca Frédérique , Gimbergues Pierre , Jacquemier Jocelyne , Houvenaeghel Gilles , Chatellier Gilles , Lécuru Fabrice 
Published: July 2011

AbstractThe purpose of this prospective multicenter study was to assess one‐step nucleic acid amplification (OSNA) for intraoperative sentinel lymph node (SLN) metastasis detection in breast cancer patients, using final histology as the reference standard. OSNA results were also compared to intraoperative histology SLN evaluation and to standard clinicopathological risk markers. For this study, fresh SLNs were cut in four blocks, and alternate blocks were used for OSNA and histology. CK19 mRNA copy number was categorized as strongly positive, positive or negative. Positive histology was defined as presence of macrometastasis or micrometastasis. When discrepancies occurred, the entire SLNs were subjected to histological studies and the node lysates to additional molecular studies. Five hundred three SLN samples from 233 patients were studied. Mean time to evaluate two SLNs was 40 min. Sensitivity per patient was 91.4% (95% CI, 76.9–98.2%), specificity 93.3% (95% CI, 88.6–96.6%), positive likelihood ratio 13.7 and negative likelihood ratio 0.1. Sensitivity was 63.6% for frozen sections and 47.1% for touch imprint cytology. Both methods were 100% specific. Positive histology and positive OSNA were significantly associated with highest clinical stage, N1 status and vascular invasion; and OSNA results correlated with HER2/neu status and benefited patients with negative histology. These findings show that OSNA assay can allow detection of SLN metastasis in breast cancer patients intraoperatively with a good sensitivity, thus minimizing the need for second surgeries for axillary lymph node detection.
PED/PEA‐15 controls fibroblast motility and wound closure by ERK1/2‐dependent mechanisms
Authors: Buonomo Roberta , Giacco Ferdinando , Vasaturo Angela , Caserta Sergio , Guido Stefano , Pagliara Valentina , Garbi Corrado , Mansueto Gelsomina , Cassese Angela , Perruolo Giuseppe , Oriente Francesco , Miele Claudia , Beguinot Francesco , Formisano Pietro 
Published: July 2011

AbstractCell migration is dependent on the control of signaling events that play significant roles in creating contractile force and in contributing to wound closure. We evaluated wound closure in fibroblasts from mice overexpressing (TgPED) or lacking ped/pea‐15 (KO), a gene overexpressed in patients with type 2 diabetes. Cultured skin fibroblasts isolated from TgPED mice showed a significant reduction in the ability to recolonize wounded area during scratch assay, compared to control fibroblasts. This difference was observed both in the absence and in the presence of mytomicin C, an inhibitor of mitosis. In time‐lapse experiments, TgPED fibroblasts displayed about twofold lower velocity and diffusion coefficient, as compared to controls. These changes were accompanied by reduced spreading and decreased formation of stress fibers and focal adhesion plaques. At the molecular level, TgPED fibroblasts displayed decreased RhoA activation and increased abundance of phosphorylated extracellular signal‐regulated kinase 1/2 (ERK1/2). Inhibition of ERK1/2 activity by PD98059 restored RhoA activation, cytoskeleton organization and cell motility, and almost completely rescued wound closure of TgPED fibroblasts. Interestingly, skin fibroblasts isolated from KO mice displayed an increased wound closure ability. In vivo, healing of dorsal wounds was delayed in TgPED and accelerated in KO mice. Thus, PED/PEA‐15 may affect fibroblast motility by a mechanism, at least in part, mediated by ERK1/2. J. Cell. Physiol. 227: 2106–2116, 2012. © 2011 Wiley Periodicals, Inc.