bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lipoprotein Subclasses Determined by Nuclear Magnetic Resonance Spectroscopy and Coronary Atherosclerosis in Patients with Rheumatoid Arthritis
Authors: CHUNG CECILIA P. , OESER ANNETTE , RAGGI PAOLO , SOKKA TUULIKKI , PINCUS THEODORE , SOLUS JOSEPH F. , LINTON MACRAE F. , FAZIO SERGIO , STEIN C. MICHAEL 
Published: June 2010

Objective.Patients with rheumatoid arthritis (RA) are at increased risk of atherosclerosis, but routine lipid measurements differ little from those of people without RA. We examined the hypothesis that lipid subclasses determined by nuclear magnetic resonance spectroscopy (NMR) differed in patients with RA compared to controls and are associated with disease activity and the presence of coronary-artery atherosclerosis.Methods.We measured lipoprotein subclasses by NMR in 139 patients with RA and 75 control subjects. Lipoproteins were classified as large low-density lipoprotein (LDL; diameter range 21.2–27.0 nm), small LDL (18.0–21.2 nm), large high-density lipoprotein (HDL; 8.2–13.0 nm), small HDL (7.3–8.2 nm), and total very low-density lipoprotein (VLDL; ≥ 27 nm). All subjects underwent an interview and examination; disease activity was quantified by the 28-joint Disease Activity Score (DAS28) and coronary artery calcification (CAC) was measured with electron-beam computed tomography.Results.Concentrations of small HDL particles were lower in patients with RA (18.2 ± 5.4 nmol/l) than controls (20.0 ± 4.4 nmol/l; p = 0.003). In patients with RA, small HDL concentrations were inversely associated with DAS28 (rho = −0.18, p = 0.04) and C-reactive protein (rho = −0.25, p = 0.004). Concentrations of small HDL were lower in patients with coronary calcification (17.4 ± 4.8 nmol/l) than in those without (19.0 ± 5.8 nmol/l; p = 0.03). This relationship remained significant after adjustment for the Framingham risk score and DAS28 (p = 0.025). Concentrations of small LDL particles were lower in patients with RA (1390 ± 722 nmol/l) than in controls (1518 ± 654 nmol/l; p = 0.05), but did not correlate with DAS28 or CAC.Conclusion.Low concentrations of small HDL particles may contribute to increased coronary atherosclerosis in patients with RA.
Canadian Recommendations for Use of Methotrexate in Patients with Rheumatoid Arthritis
Authors: KATCHAMART WANRUCHADA , BOURRÉ-TESSIER JOSIANE , DONKA TIMEA , DROUIN JULIE , ROHEKAR GINA , BYKERK VIVIAN P. , HARAOUI BOULOS , LECLERQ SHARON , MOSHER DIANNE P. , POPE JANET E. , SHOJANIA KAM , THOMSON JOHN , THORNE J. CARTER , BOMBARDIER CLAIRE 
Published: June 2010

Objective.To develop recommendations for the use of methotrexate (MTX) in patients with rheumatoid arthritis.Methods.Canadian rheumatologists who participated in the international 3e Initiative in Rheumatology (evidence, expertise, exchange) in 2007–2008 formulated 5 unique Canadian questions. A bibliographic team systematically reviewed the relevant literature on these 5 topics. An expert committee consisting of 26 rheumatologists from across Canada was convened, and a set of recommendations was proposed based on the results of systematic reviews combined with expert opinions using a nominal group consensus process.Results.The 5 questions addressed drug interactions, predictors of response, strategies to reduce non-serious side effects, variables to assess clinical response, and incorporating patient preference into decision-making. The systematic review retrieved 93 pertinent articles; this evidence was presented to the expert committee during the interactive workshop. After extensive discussion and voting, a total of 9 recommendations were formulated: 2 on drug interactions, 1 on predictors of response, 2 on strategies to reduce non-serious side effects, 3 on variables to assess clinical response, and 1 on incorporating patient preferences into decision-making. The level of evidence and the strength of recommendations are reported. Agreement among panelists ranged from 85% to 100%.Conclusion.Nine recommendations pertaining to the use of MTX in daily practice were developed using an evidence-based approach followed by expert/physician consensus with high level of agreement.
ADAMTS5 Is a Biomarker for Prediction of Response to Infliximab in Patients with Rheumatoid Arthritis
Authors: TSUZAKA KENSEI , ITAMI YUKA , TAKEUCHI TSUTOMU , SHINOZAKI NAOSHI , MORISHITA TETSUO 
Published: June 2010

Objective.To identify a biomarker for prediction of the response to infliximab (IFX) in patients with rheumatoid arthritis (RA), we focused on a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) that seems to play a key role in aggrecan degradation in cartilage.Methods.Seventy-three randomly selected patients with active RA were treated with IFX. Peripheral blood samples were collected at baseline and ADAMTS5 messenger RNA (mRNA) was quantified using real-time polymerase chain reaction.Results.Baseline ADAMTS5 mRNA levels in the good responder group were significantly lower (1.84 ± 1.56; p = 0.0408) than those in the moderate and nonresponder groups (2.54 ± 1.70) at 38 weeks of treatment with IFX. The 28-joint count Disease Activity Score (DAS28) at 38 weeks of treatment was significantly lower in the low ADAMTS5 group (2.30 ± 1.28; p = 0.0038) than in the high ADAMTS5 group (3.90 ± 1.61). The percentage reduction of the DAS28 was significantly higher in the low ADAMTS5 group (52.5% ± 28.8%; p = 0.0156) than in the high ADAMTS5 group (29.4% ± 27.2%). Further, the Δ Health Assessment Questionnaire (ΔHAQ) score, an estimate of the improvement in the HAQ score, at 38 weeks of treatment was significantly higher in the low ADAMTS5 group (1.18 ± 0.60; p = 0.0102) than in the high ADAMTS5 group (0.21 ± 0.78). The positive predictive value of a low baseline ADAMTS5 level for predicting good response and remission (DAS28 < 2.6 at 38 weeks) was 90.0% and 70.0%, respectively.Conclusion.The baseline ADAMTS5 mRNA level is a candidate biomarker for prediction of the response to IFX in patients with RA.
Effects of phosphorus‐deficient diets on the carbon and phosphorus balance of Daphnia magna
Authors: DeMott William R. , Gulati Ramesh D. , Siewertsen Klaas 
Published: May 2010

We used laboratory growth and feeding experiments to study the balance of carbon (C) and phosphorus (P) in Daphnia magna. Daphnia were fed high‐concentration mixtures of P‐sufficient and P‐deficient green algae (Scenedesmus acutus; molar C:P 80 and 900, respectively) or mixtures of P‐deficient Scenedesmus and a P‐rich cyanobacterium (Synechococcus elongatus; C:P = 60). P‐deficient diets resulted in, rapid declines in the growth rates of Daphnia and unexpected declines in Daphnia's P‐to‐dry‐weight ratio. P‐deficient Scenedesmus and P‐rich Synechococcus supported poor growth as sole foods but improved growth in mixtures. A 2‐d experiment with a dietary C:P gradient from 120 to 900 revealed a linear relation between Daphnia's final P‐to‐dry‐weight ratio and its growth rate (r2 = 0.92). Growth in mass (mean ± SE) ranged from 0.54 ± 0.01 to 0.17 ± 0.02 d−1 whereas final specific P content ranged from 1.47 ± 0.01% to 1.08 ± 0.02%.Supporting stoichiometric theory, experiments with dual‐labeled (14C/32P) Scenedesmus showed that C assimilation efficiency declines as the C:P ratio of the diet increases. Adding unlabeled P‐deficient algae reduced the C assimilation efficiency for labeled P‐sufficient algae, whereas adding unlabeled P‐rich algae improved the C assimilation efficiency for labeled P‐deficient algae. C gross growth efficiency (production/ingestion) steadily decreased with declining dietary P. In contrast, P gross growth efficiency exhibited a unimodal pattern with reduced values for both P‐rich and strongly P‐deficient resources. The unexpected decline with P‐deficient diets was apparently due to low but consistent P‐release rates by strongly P‐limited Daphnia. Mass‐balance calculations confirmed that Daphnia was a strong sink for P when resources exhibited intermediate levels of P deficiency. Our results support stoichiometric theory but show that P‐deficient diets lead to significant declines in Daphnia's P content.
Sediment nutrient dynamics on the South Atlantic Bight continental shelf
Authors: Marinelli Roberta L. , Jahnke Richard A. , Craven Deborah B. , Nelson James R. , Eckman James E. 
Published: May 2010

Continental shelf sediments on the South Atlantic Bight (SAB) consist of relict sands that, at depths ranging from 14–45 m, fall within the photic zone and are sites in which significant rates of benthic primary production are observed. Thus, SAB seafloor sediments are a source of organic matter to the shelf system and are possibly a sink for nutrients regenerated within the sediments. We have investigated the nutrient dynamics in SAB shelf sediments along two transects (off the coasts of Georgia and Florida) as part of a study that addresses the significance of benthic primary production in terms of overall shelf biogeochemistry. Sandy sediments were sampled with a newly designed corer that permits retention of pore water in highly permeable sands and thus avoids commonly encountered “washout” problems. Nutrient (ammonium, silicate, nitrate + nitrite, and phosphate) distributions from sediments along both transects show substantial variation in concentration magnitudes and profile shapes over short horizontal spatial scales (meters). Laboratory experiments and numerical models of diagenetic processes in these sediments suggest that (1) pore‐water advection, driven by current flows over wave ripples and bioturbational features, is likely an important transport process in promoting nutrient exchange in these porous sands (more so than irrigation), and (2) reaction rates in SAB sediments are rapid and are comparable to those in nearshore muddy habitats. In spite of this variation and the apparently high rates of advective transport, time series measurements show a gradual increase in depth‐integrated nutrient concentrations at one station along the Georgia transect from the spring through the fall. This increase is probably related to elevations in temperature and metabolic rates in sediments during the warmer summer months.Measured oxygen and nutrient fluxes across the sediment‐water interface in paired transparent “light” chambers and opaque “dark” chambers did not conform to trends observed in shallow water systems, where oxygen is typically evolved and nutrients are consumed in the light (versus oxygen that is consumed and nutrients that are evolved in the dark). The absence of measurable or consistent fluxes on the SAB shelf is likely the result of low concentrations of nutrients in both the water column and the upper sediment layers. However, rapid regeneration rates in sediments and generally higher nutrient concentrations in deeper sediment layers suggest that sediments are an important source of the nutrients that fuel benthic primary production. Although ammonium is rapidly produced in these oxic sands, nitrate concentrations are uniformly low, and measurable nitrate generally appears in the oxic sedimentary layers. The absence of high nitrate concentrations in the suboxic or anoxic zone suggests that denitrification may not be an important process in SAB shelf sediments.
Exploring the Effectiveness of Occupational Therapy Interventions, Other Than the Sensory Integration Approach, With Children and Adolescents Experiencing Difficulty Processing and Integrating Sensory Information
Authors: Polatajko Helene J. , Cantin Noemi 
Published: June 2010

AbstractThis literature review was completed as part of the Evidence-Based Literature Review Project of the American Occupational Therapy Association to explore the effectiveness of occupational therapy interventions with children and adolescents experiencing difficulty processing and integrating sensory information. This part of the review focused on interventions other than the sensory integration approach. Twenty articles (reporting on 21 studies) met the inclusion criteria. This systematic review found that children with difficulty processing and integrating sensory information and difficulties with the performance of daily occupations can benefit from intervention. However, the great variability that characterizes this literature in terms of populations, interventions, and study quality precludes the formation of any firm conclusions regarding specific approaches. There is an urgent need for well-controlled studies examining the effectiveness of frequently used pediatric occupational therapy interventions with well-defined, homogeneous populations on outcomes that target participation in everyday life.
Relationships Between Stereotyped Movements and Sensory Processing Disorders in Children With and Without Developmental or Sensory Disorders
Authors: Gal Eynat , Dyck Murray J. , Passmore Anne 
Published: June 2010

Abstract
OBJECTIVE. Stereotyped movements (SM) are a defining characteristic of autism but are also present in children with a range of sensory and developmental disorders. We examined whether the severity of sensory processing disorders (SPD) was associated with the severity of SM and whether SPD accounted for between-group differences in SM.
METHOD. The Short Sensory Profile and the Stereotyped and Self-Injurious Movements Interview were administered to children with autism, intellectual disability, visual impairment, and hearing impairment and to typically developing children.
RESULTS. SPD predicted the severity of SM in all samples and accounted for differences in SM between the groups. Other differences in the severity of SM were the result of diagnosis and the interaction between diagnosis and an intellectual disability.
CONCLUSION. SPD may be a source of SM, but functional connections between these phenomena will need to be tested in future research. Implications for occupational performance are addressed.
Quality of Life in American Indian Women With Arthritis or Diabetes
Authors: Poole Janet L. , Cordova Jennifer Schukar , Sibbitt Wilmer L. , Skipper Betty 
Published: June 2010

Abstract
OBJECTIVE. We investigated quality of life (QOL) in American Indian women with different chronic diseases.
METHOD. Sixty American Indian women with diabetes mellitus (DM), rheumatoid arthritis (RA), or both DM and RA (DM + RA), and healthy control women received evaluations of joint motion, hand strength dexterity, pain, activity and participation limitations and QOL.
RESULTS. The DM + RA and RA groups had significantly more pain, less joint motion, decreased hand strength, and more activity limitations. Participation was similar for all groups except the DM + RA group. Past and present QOL were similar; however, the DM + RA group reported significantly decreased future QOL.
CONCLUSION. Results suggest that the presence of more than one chronic disease affects activity and participation. Factors that related to QOL were different for each disease group, with the exception of pain. Identification of factors related to QOL can help occupational therapists identify areas for intervention.
Influence of addition of oat and lentil on the content of the detected components in bread
Authors: Bojňanská Tatiana , Vollmannová Alena , Frančáková Helena 
Published: May 2010

In this paper, the results obtained by bread products analysis made with the addition of oats and lentils, which increased its nutrition value are presented. Breads were prepared with addition of 10 %, 20 %, 30 %, 40 % and 50 % which were analyzed for Fe, Mn, Zn, Cu, Co, Ni, Cr, Pb and Cd content. Prepared products were evaluated also from viewpoint of their technological and nutritional value. Use of oat in bread increased with the addition of a quantity of 50 % content of nutritionally significant elements such as Fe (3.2 times), Mn (3.13 times), Zn (2.23 times), Cu (2.01 times) and Cr (1.2 times). The addition of lentils increased particularly Cu content (3.55 times), Zn (2.96 times) and Mn (1.29 times). None of the samples showed exceeded maximum limit (1.0 mg.kg-1) for lead. Based on the analysis results it was confirmed, that the most problematic element in our soils and subsequently in the foodstuffs is cadmium. Exceeded values (< 0.1 mg.kg-1) were detected in 8 samples from 11, in finished products the values were within the limits ranging from 0.090 mg.kg-1 Cd to 0.180 mg.kg-1 Cd.
The influence of propolis application to meat utility on ROSS 308 broiler chickens
Authors: Haščí­k Peter , Melich Martin , Kačániová Miroslava , Pál Gabriel , Mihok Michal , Čuboň Juraj , Melen Martin , Vavrišinová Klára 
Published: May 2010

The aim of the experiment was to monitor the impact of propolis extract (experimental group) for meat utility of the Ross 308 chicken. The dosage of propolis was 0.2 g.kg KKZ-1 throught the fattening (40 days). Application of propolis increased (P≤0.01) slaughter weight (+76.80 g) and carcass weight (+67.90 g) in hens compared to the control group (1790.60 g, resp. 1266.54 g). In group with roosters slaughter weight (+70.80 g) and carcass weight (+56.00 g) were also increased (P≥0.05) in the experimental group compared to control (2086.20 g, resp. 1475.20 g). Offal weight in both sexes was lower (P≥0.05) in the experimental group (135.55 g - ♀, 158.21 g - ♂) compared to control (140.75 g - ♀, 168.55 g - ♂). Carcass yield was higher in hens (P≥0.05) in the experimental group (78.71 %) versus control (78.60 %).The evaluation of meat utility Ross 308 chickens without distinction of sex did not show significant differences (P≥0.05), but a slight increase in slaughter weight and in the carcass weight in group with application of propolis extract in their fattening. Contrary slightly lower offal weight (-7.77 g) and carcass yield (-0.21 %) were found in the experimental group of chickens without distinction of sex (P≥0.05) compared to control group (weight of offal - 154.65 g, carcass yield - 78.69 %). We recommend the application of propolis as a possible supplement in the fattening of chickens, as it increases the performance parameters of meat and may also positively affect the economy of production.
Nanoporöse Metallschäume
Authors: Tappan Bryce C. , Steiner Stephen A. , Luther Erik P. 
Published: May 2010

AbstractNanoporöse Metallschäume (NMFs) werden seit langem als eine Klasse von Stoffen für leitfähige und katalytische Materialien mit großen Oberflächen untersucht. Dieser Aufsatz gibt einen Überblick über neue Strategien für die Herstellung von NMFs mit einem Schwerpunkt auf der Verbrennungssynthese und diskutiert aktuelle Anwendung von NMFs, unter anderem zur Speicherung von Wasserstoff und in der Katalyse.
Nanoporous Metal Foams
Authors: Tappan Bryce C. , Steiner Stephen A. , Luther Erik P. 
Published: May 2010

AbstractNanoporous metal foams (NMFs) have been a long sought‐after class of materials in the quest for high‐surface‐area conductive and catalytic materials. Herein we present an overview of newly developed synthetic strategies for producing NMFs along with an in‐depth discussion of combustion synthesis as a versatile and scalable approach for the preparation of nanoporous, nanostructured metal foams. Current applications of NMFs prepared using combustion synthesis are also presented including hydrogen storage and catalysis.
A Friend In Deed? Can Adolescent Girls Be Taught to Understand Relational Bullying?
Authors: James Deborah , Flynn Ann , Lawlor Maria , Courtney Pat , Murphy Niamh , Henry Bernie 
Published: May 2010

AbstractRelational aggression is common among girls. It can be distressing for the victim and may not always be recognised as a form of bullying. This paper evaluates a school–based intervention designed to help girls understand relational bullying. Girls from a single‐sex school completed a two‐stage evaluation of the intervention. Students showed greater awareness of relational bullying after the intervention and indicated that it would influence them to change their behaviour. At follow‐up, retention of knowledge was good. Students reported greater self‐monitoring of behaviour and less exclusivity. While this is encouraging, we cannot conclude that all negative behaviours ceased. Implications and limitations of this study are discussed. Copyright © 2010 John Wiley & Sons, Ltd.
Formation of Superoxo Species by Interaction of O2 with Na Atoms Deposited on MgO Powders: A Combined Continuous‐Wave EPR (CW‐EPR), Hyperfine Sublevel Correlation (HYSCORE) and DFT Study
Authors: Napoli Francesco , Chiesa Mario , Giamello Elio , Preda Gloria , Di Valentin Cristiana , Pacchioni Gianfranco 
Published: May 2010

AbstractThe formation of O2− radical anions by contact of O2 molecules with a Na pre‐covered MgO surface is studied by a combined EPR and quantum chemical approach. Na atoms deposited on polycrystalline MgO samples are brought into contact with O2. The typical EPR signal of isolated Na atoms disappears when the reaction with O2 takes place and new paramagnetic species are observed, which are attributed to different surface‐stabilised O2− radicals. Hyperfine sublevel correlation (HYSCORE) spectroscopy allows the superhyperfine interaction tensor of O2−Na+ species to be determined, demonstrating the direct coordination of the O2− adsorbate to surface Na+ cations. DFT calculations enable the structural details of the formed species to be determined. Matrix‐isolated alkali superoxides are used as a standard to enable comparison of the formed species, revealing important and unexpected contributions of the MgO matrix in determining the electronic structure of the surface‐stabilised Na+O2− complexes.
ChemInform Abstract: A New Structure Model for Ba3Nb2O8: A HREM Study.
Authors: Garcia‐Gonzalez E. , Parras M. , Gonzalez‐Calbet J. M. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Physical Properties of a Novel Rare‐Earth Boron Carbide Compound Sc3B0.75C3.
Authors: Mori Takao , Shi Ying , Tanaka Takaho 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Resolution Photoluminescence Spectrum of GdVO4:Eu3+.
Authors: Zhang Qing‐li , Guo Chang‐xin , Shi Chao‐shu , Lue Shao‐zhe 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Development of Carbon Nanotubes/RuO2×xH2O Electrodes for Electrochemical Capacitors.
Authors: Ma Renzhi , Wei Bingqing , Xu Cailu , Liang Ji , Wu Dehai 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chromium Sublattice Magnetic Ordering in a Compound of the ThCr2Si2 Type Structure: HoCr2Si2.
Authors: Moze O. , Hofmann M. , Buschow K. H. J. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.