bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of “breathable” panty liners on the female lower genital tract
Authors: Giraldo Paulo C. , Amaral Rose L.G. , Juliato Cássia , Eleutério José , Brolazo Eliane , Gonçalves Ana K.S. 
Published: July 2011

AbstractObjectiveTo evaluate whether the use of “breathable” panty liners (BPLs) alters the normal vaginal flora, increases the incidence of bacterial vaginosis and/or vaginal candidiasis, or causes vulvar irritation.MethodsA randomized controlled trial assessed the vaginal ecosystem of women without complaints of vaginal discharge. The study group (n = 53) wore BPLs for 10–12 hours each day for 75 consecutive days, whereas the control group (n = 54) wore only their usual underwear. At each of 6 visits during 3 menstrual cycles, participants underwent gynecologic examination with colposcopic evaluation and pH measurement, in addition to assessment of vaginal microbial flora, intensity of inflammatory processes, and presence of vaginal candidiasis/bacterial vaginosis in Gram‐stained smears.ResultsAfter 75 consecutive days of BPL use, 40/44 (90.9%) and 42/44 (95.5%) women reported no complaints of vaginal discharge or vulvar itching/burning, respectively. There was no significant difference between the study group and the control group with regard to positive vaginal fungus cultures (5/44 [11.4%] vs 8/50 [16.0%]; P = 0.7848) or bacterial vaginosis (3/44 [6.8%] vs 2/50 [4.0%]; P = 0.7974) at the end of the study period.ConclusionAfter 75 days of BPL use, there was no significant increase in vulvovaginal candidiasis, bacterial vaginosis, vulvovaginal irritation, or vulvovaginal inflammation.
Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer
Authors: Mercier Pierre-Luc , Bachvarova Magdalena , Plante Marie , Gregoire Jean , Renaud Marie-Claude , Ghani Karim , Têtu Bernard , Bairati Isabelle , Bachvarov Dimcho 
Published: July 2011

AbstractIn attempt to discover novel aberrantly hypermethylated genes with putative tumor suppressor function in epithelial ovarian cancer (EOC), we applied expression profiling following pharmacologic inhibition of DNA methylation in EOC cell lines. Among the genes identified, one of particular interest wаs DOK1, or downstream of tyrosine kinase 1, previously recognized as a candidate tumor suppressor gene (TSG) for leukemia and other human malignancies. Using bisulfite sequencing, we determined that a 5′‐non‐coding DNA region (located at nt −1158 to −850, upstream of the DOK1 translation start codon) was extensively hypermethylated in primary serous EOC tumors compared with normal ovarian specimens; however, this hypermethylation was not associated with DOK1 suppression. On the contrary, DOK1 was found to be strongly overexpressed in serous EOC tumors as compared to normal tissue and importantly, DOK1 overexpression significantly correlated with improved progression‐free survival (PFS) values of serous EOC patients. Ectopic modulation of DOK1 expression in EOC cells and consecutive functional analyses pointed toward association of DOK1 expression with increased EOC cell migration and proliferation, and better sensitivity to cisplatin treatment. Gene expression profiling and consecutive network and pathway analyses were also confirmative for DOK1 association with EOC cell migration and proliferation. These analyses were also indicative for DOK1 protective role in EOC tumorigenesis, linked to DOK1‐mediated induction of some tumor suppressor factors and its suppression of pro‐metastasis genes. Taken together, our findings are suggestive for a possible tumor suppressor role of DOK1 in EOC; however its implication in enhanced EOC cell migration and proliferation restrain us to conclude that DOK1 represents a true TSG in EOC. Further studies are needed to more completely elucidate the functional implications of DOK1 and other members of the DOK gene family in ovarian tumorigenesis.
Evolution of Invertebrate Deuterostomes and Hox/ParaHox Genes
Authors: Ikuta Tetsuro 
Published: July 2011

Abstract
Transcription factors encoded by Antennapedia-class homeobox genes play crucial roles in controlling development of animals, and are often found clustered in animal genomes. The Hox and ParaHox gene clusters have been regarded as evolutionary sisters and evolved from a putative common ancestral gene complex, the ProtoHox cluster, prior to the divergence of the Cnidaria and Bilateria (bilaterally symmetrical animals). The Deuterostomia is a monophyletic group of animals that belongs to the Bilateria, and a sister group to the Protostomia. The deuterostomes include the vertebrates (to which we belong), invertebrate chordates, hemichordates, echinoderms and possibly xenoturbellids, as well as acoelomorphs. The studies of Hox and ParaHox genes provide insights into the origin and subsequent evolution of the bilaterian animals. Recently, it becomes apparent that among the Hox and ParaHox genes, there are significant variations in organization on the chromosome, expression pattern, and function. In this review, focusing on invertebrate deuterostomes, I first summarize recent findings about Hox and ParaHox genes. Next, citing unsolved issues, I try to provide clues that might allow us to reconstruct the common ancestor of deuterostomes, as well as understand the roles of Hox and ParaHox genes in the development and evolution of deuterostomes.
Genetic Flux Between H1 and H2 Haplotypes of the 17q21.31 Inversion in European Population
Authors: Deng Libin , Tang Xiaoli , Hao Xiangwen , Chen Wei , Lin Jiari , Yu Yangyu , Zhang Dake , Zeng Changqing 
Published: July 2011

Abstract
The chromosome 17q21.31 inversion is a 900-kb common structural polymorphism found primarily in European population. Although the genetic flux within inversion region was assumed to be considerable suppressed, it is still unclear about the details of genetic exchange between the H1 (non-inverted sequence) and H2 (inverted sequence) haplotypes of this inversion. Here we describe a refined map of genetic exchanges between pairs of gene arrangements within the 17q21.31 region. Using HapMap phase II data of 1,546 single nucleotide polymorphisms, we successfully deduced 96 H1 and 24 H2 haplotypes in European samples by neighbor-joining tree reconstruction. Furthermore, we identified 15 and 26 candidate tracts with reciprocal and non-reciprocal genetic exchanges, respectively. In all 15 regions harboring reciprocal exchange, haplotypes reconstructed by clone sequencing did not support these exchange events, suggesting that such signals of exchange between two sister chromosomes in certain heterozygous individual were caused by phasing error regions. On the other hand, the finished clone sequencing across 4 of 26 tracts with non-reciprocal genetic flux confirmed that this kind of genetic exchange was caused by gene conversion. In summary, as crossover between pairs of gene arrangements had been considerably suppressed, gene conversion might be the most important mechanism for genetic exchange at 17q21.31.
ON ONE-DIMENSIONAL LEIBNIZ CENTRAL EXTENSIONS OF A FILIFORM LIE ALGEBRA
Authors: RAKHIMOV ISAMIDDIN S. , HASSAN MUNTHER A. 
Published: July 2011

AbstractThe paper deals with the classification of Leibniz central extensions of a filiform Lie algebra. We choose a basis with respect to which the multiplication table has a simple form. In low-dimensional cases isomorphism classes of the central extensions are given. In the case of parametric families of orbits, invariant functions (orbit functions) are provided.
ON HYBRID SEQUENCES BUILT FROM NIEDERREITER–HALTON SEQUENCES AND KRONECKER SEQUENCES
Authors: HOFER ROSWITHA , KRITZER PETER 
Published: July 2011

AbstractWe discuss the distribution properties of hybrid sequences whose components stem from Niederreiter–Halton sequences on the one hand, and Kronecker sequences on the other. In this paper, we give necessary and sufficient conditions on the uniform distribution of such sequences, and derive a result regarding their discrepancy. We conclude with a short summary and a discussion of topics for future research.
MATTHEW TINDAL'SRIGHTS OF THE CHRISTIAN CHURCH(1706) AND THE CHURCH–STATE RELATIONSHIP
Authors: LEVITIN DMITRI 
Published: July 2011

ABSTRACTMatthew Tindal's Rights of the Christian church (1706), which elicited more than thirty contemporary replies, was a major interjection in the ongoing debates about the relationship between church and state in late seventeenth- and early eighteenth-century England. Historians have usually seen Tindal's work as an exemplar of the ‘republican civil religion’ that had its roots in Hobbes and Harrington, and putatively formed the essence of radical whig thought in the wake of the Glorious Revolution. But this is to misunderstand theRights. To comprehend what Tindal perceived himself as doing we need to move away from the history of putatively ‘political’ issues to the histories of ecclesiastical jurisprudence, patristic scholarship, and biblical exegesis. The contemporary significance of Tindal's work was twofold: methodologically, it challenged Anglican patristic scholarship as a means of reaching consensus on modern ecclesiological issues; positively, it offered a powerful argument for ecclesiastical supremacy lying in crown-in-parliament, drawing on a legal tradition stretching back to Christopher St Germain (1460–1540) and on Tindal's own legal background. Tindal's text provides a case study for the tentative proposition that ‘republicanism’, whether as a programme or a ‘language’, had far less impact on English anticlericalism and contemporary debates over the church–state relationship than the current historiography suggests.
TRANSOCEANIC COMMEMORATION AND CONNECTIONS BETWEEN BENGALI BRAHMOS AND BRITISH AND AMERICAN UNITARIANS
Authors: MIDGLEY CLARE 
Published: July 2011

ABSTRACTThis article traces the history of the commemoration in Britain, India, and America of leading Bengali religious and social reformer, Rammohun Roy, from his death in Britain in 1833 through to the publication of the first substantial account of his life and work in 1900. It reveals the vital part that commemorative processes played in creating a sense of imagined community among liberal religious groups who were in the vanguard of social reform movements in India, Britain, and the United States. The groups under consideration are the Brahmo Samaj, an organization founded by Roy to reform Hinduism, and Unitarians, Protestant dissenters who rejected the orthodox Christian doctrine of the Holy Trinity and the evangelical approach to missionary work. Bridging the study of transatlantic and imperial networks, the article explores a culture of commemoration that emphasized affinity rather than difference between groups whose members were unequally positioned in colonial discourse as on opposite sides of the colonizer–colonized, Hindu–Christian, and East–West divides. It exposes the commemoration of Roy as a complex and contested process, creating both ‘localized’ and ‘globalized’ collective memories. These reveal the possibilities for, and limitations on, cross-cultural interchange in an age of global Christian mission and British imperial power.
WRITING ABOUT VIOLENCE IN THE TUDOR KINGDOMS
Authors: RAPPLE R. 
Published: July 2011

ABSTRACTDespite differing historiographical traditions, the histories of Tudor England and Ireland often face similar problems, not least how best to narrate and analyse episodes of state and non-state violence in a satisfying way. Latterly, sophisticated models for dealing with this have emerged in treatments of English popular politics. These works succeed in eschewing both inherited ideas of English exceptionalism and the ‘enclosure’ of social history. They also offer a compelling and holistic view of social and political interactions in the past from a number of vantage points. Many recent treatments of sixteenth-century Irish history, by contrast, have centred on atrocity and even genocide. This narrower focus does not preclude important scholarship, but its thematic and methodological limitations hamper that scholarship's broader non-polemical value. The appreciation of Tudor Ireland's status as a political society and the close scrutiny of that political society and its actors is a necessity. It offers just as promising an embarkation point for sophisticated and interesting studies as the study of Tudor English popular politics.
Micarea capitata, a new bryophilous lichen from Sweden
Authors: SVENSSON Måns , THOR Göran 
Published: July 2011

AbstractThe diminutive species Micarea capitata is described from north-western Sweden. It has been found at two localities in boreal forests where it grew on the bryophyte Hylocomium splendens. Micarea capitata is distinguished by small (0·10–0·35 mm diam.) black apothecia, (0–)1-septate ascospores and a mottled, darkly pigmented hypothecium.
Tetramelas thiopolizuscomb. nov. with a key to all known species ofTetramelas
Authors: GIRALT Mireia , CLERC Philippe 
Published: July 2011

AbstractThe study of the type and additional material ofBuellia andicola, B. hypophanaandB. reagenshas shown that these taxa are conspecific withB. thiopoliza. Buellia thiopolizais a muscicolous species growing at middle to high altitudes in the mountains of both hemispheres. It is easily recognized by its K+ purple-red yellow pigment mainly concentrated in the hypothecium, and by the presence of xanthones in the thallus and the apothecial tissues. The new combinationTetramelas thiopolizusis proposed. A key to all knownTetramelasspecies is included. The also muscicolousBuellia hypoleucais reduced to synonymy withPhaeorrhiza sareptanavar.sphaerocarpa.
Two new species in the lichen family Graphidaceae from India
Authors: SHARMA Bharati O. , KHADILKAR Pradnya 
Published: July 2011

AbstractGraphis parvicarpa and Pallidogramme bengalense are described as new to science from India. Graphis parvicarpa is characterized by a striate excipulum, inspersed hymenium, muriform ascospores, and norstictic acid in the thallus. Pallidogramme bengalense is characterized by a striate exciple, muriform, hyaline to pale brown ascospores, inspersed hymenium and no lichen substances in the thallus.
The Caloplaca crenulatella species complex; its intricate taxonomy and description of a new species
Authors: VONDRÁK Jan , ŘÍHA Pavel , REDCHENKO Olexii , VONDRÁKOVÁ Olga , HROUZEK Pavel , KHODOSOVTSEV Alexander 
Published: July 2011

AbstractThe Caloplaca crenulatella species complex is monophyletic, based on analysis of ITS nrDNA sequences. It is characterized mainly by its ascospores and a simplified thallus. Caloplaca aquensis, C. borysthenica, C. interfulgens, C. lactea, C. marmorata and C. tominii represent well-defined monophyletic lineages within it. Caloplaca diffusa, described here as a new species, is a well-supported lineage with a distinctive phenotype. Caloplaca crenulatella s. lat. and C. ferrarii s. lat. are heterogeneous taxa appearing in four and two places respectively within our tree. Caloplaca ochracea also belongs to the group, although it has different ascospore characters. Caloplaca gyalolechiaeformis and C. pseudocitrina are later synonyms of C. tominii. Arctic and North American sorediate specimens morphologically very close to C. tominii represent a separate lineage recently recognized as C. erichansenii. The North American Caloplaca nashii has a C. crenulatella-like phenotype but does not belong to the C. crenulatella complex. The identities of Caloplaca lacteoides and Caloplaca epigaea are not clear, but the latter may be a terricolous ecotype of one of the entities within C. crenulatella s. lat. A key to the European species of the group is provided.
Molecular support for the recognition of theMycoblastus fucatusgroup as the new genusViolella(Tephromelataceae,Lecanorales)
Authors: SPRIBILLE Toby , GOFFINET Bernard , KLUG Barbara , MUGGIA Lucia , OBERMAYER Walter , MAYRHOFER Helmut 
Published: July 2011

AbstractThe crustose lichen genusMycoblastusin the Northern Hemisphere includes eight recognized species sharing large, simple ascospores produced 1–2 per ascus in strongly pigmented biatorine apothecia. The monophyly ofMycoblastusand the relationship of its various species toTephromelataceaehave never been studied in detail. Data from ITS rDNA and the genes coding for translation elongation factor 1-α and DNA replication licensing factor mini-chromosome maintenance complex 7 support the distinctness ofMycoblastuss. str. from the core of theTephromelataceae, but recoverM. fucatusand an undescribed Asian species as strongly supported within the latter group. We propose accommodating these two species in a new genus,Violella, which is characterized by its brownish inner ascospore walls, Fucatus-violet hymenial pigment granules and secondary chemistry, and discuss the position ofViolellarelative toCalvitimelaandTephromela. We describe the new speciesViolella wangiiT. Sprib. & Goffinet to accommodate a new species with roccellic acid from Bhutan, China, India and the Russian Far East. We also excludeMycoblastus indicusAwasthi & Agarwal from the genusMycoblastusand propose for it the new combinationMalmidea indica(Awasthi & Agarwal) Hafellner & T. Sprib.
Familial influence and childhood trauma in female alcoholism
Authors: Magnusson Å. , Lundholm C. , Göransson M. , Copeland W. , Heilig M. , Pedersen N. L. 
Published: July 2011

BackgroundTo assess the role of genetic and environmental factors in female alcoholism using a large population-based twin sample, taking into account possible differences between early and late onset disease subtype.MethodTwins aged 20–47 years from the Swedish Twin Registry (n=24 119) answered questions to establish lifetime alcohol use disorders. Subjects with alcoholism were classified for subtype. Structural equation modeling was used to quantify the proportion of phenotypic variance due to genetic and environmental factors and test whether heritability in women differed from that in men. The association between childhood trauma and alcoholism was then examined in females, controlling for background familial factors.ResultsLifetime prevalence of alcohol dependence was 4.9% in women and 8.6% in men. Overall, heritability for alcohol dependence was 55%, and did not differ significantly between men and women, although women had a significantly greater heritability for late onset (type I). Childhood physical trauma and sexual abuse had a stronger association with early onset compared to late onset alcoholism [odds ratio (OR) 2.54, 95% confidence interval (CI) 1.53–3.88 and OR 2.29, 95% CI 1.38–3.79 respectively]. Co-twin analysis indicated that familial factors largely accounted for the influence of physical trauma whereas the association with childhood sexual abuse reflected both familial and specific effects.ConclusionsHeritability of alcoholism in women is similar to that in men. Early onset alcoholism is strongly association with childhood trauma, which seems to be both a marker of familial background factors and a specific individual risk factor per se.
The first privatisation policy in Latin America: selling state-owned enterprises in 1948-1950 Puerto Rico
Authors: Bel Germà 
Published: July 2011

AbstractIn the 1940s, when the governor of Puerto Rico was still appointed by the U.S. president, a large state-owned enterprise (SOE) sector was established. Later, in 1948-1950, the island's first elected government privatised these SOEs. This paper documents both the creation of the SOE sector and its privatisation, and analyses the role played by ideology, political interests and economic concerns in the decision to privatise. Whereas ideological factors might have played a significant role in the building of the SOE sector, the privatisation process was driven by economic factors. In the cement sector, the competing private firm was more efficient and the SOEs in other sectors with no private competitors in the island showed permanent losses.
Serological evidence of Toscana virus infection in Portuguese patients
Authors: AMARO F. , LUZ T. , PARREIRA P. , MARCHI A. , CIUFOLINI M. G. , ALVES M. J. 
Published: July 2011

SUMMARYToscana virus (TOSV) is an emergingPhlebovirusof growing interest as a human pathogen in the Mediterranean Basin. In Portugal, however, little is known about the prevalence of TOSV infection. The aim of this work was to perform a seroprevalence study in patients with requests for laboratory diagnosis of vector-borne viruses. A total of 538 patients with and without neurological signs from 2004 to 2008 were studied by in-house indirect immunofluorescence assay and commercial enzyme-linked immunosorbent assays. A prevalence of 4·2% for IgG antibodies was found in the group of patients with neurological signs. Five (3%) of these had recent infections. In the group with no neurological signs, the IgG prevalence was 1·3%. Two samples, belonging to two patients, were also confirmed with plaque reduction neutralization tests with the TOSV ISS. Phl.3 Italian strain. This work showed that TOSV is present and causing disease from north to south in Portugal. The probable circulation of different phlebovirus serotypes in Portugal emphasizes the need for further studies.
The occurrence of rabies in pre-Columbian Central America: an historical search
Authors: VOS A. , NUNAN C. , BOLLES D. , MÜLLER T. , FOOKS A. R. , TORDO N. , BAER G. M. 
Published: July 2011

SUMMARYRabies is considered one of the oldest infectious diseases known to humans. However, the first written reports on rabies cases in the Americas did not appear until the first decade of the 18th century from Mexico. In an attempt to clarify if the disease was already present in pre-Columbian times, we searched for evidence in the Maya and Aztec cultures. Other sources of information were early manuscripts written by the conquistadors and early explorers. We did not identify any unequivocal direct evidence that the disease rabies was known in pre-Columbian Central America but sufficient circumstantial evidence is available suggesting that (bat) rabies was already present in these early times.
Exaggerated fear in the early Islamic Renunciant Tradition
Authors: MELCHERT CHRISTOPHER 
Published: July 2011

AbstractThe Sunni tradition of the ninth and tenth centuries often reports Muslims from the seventh and eighth centuries so fearful of God and the Last Judgement that they wished they had never been born, wept uncontrollably, and otherwise carried on as we seldom hear of from later centuries. My first object is therefore to make out what these fearers were up to. To look forward, I would characterise the piety on display as being intenselyascetical. It is about insecurity and divine transcendence, not trust and nearness to God. The fearers seem to have cultivated anxiousness to maintain their devotion and prevent complacency. My second object is to make out why such exaggerated fear evidently faded away in the later eighth century. I tend to think that fear had to be moderated with the development of Sunni theology in the ninth century, which made it necessary to stress the prospect of salvation for all Muslims, and of a Sunni piety that eschewed extreme practices unsuitable for everyone to undertake.