bluuebunny/crossref_metadata_2025_split huggingface dataset:
Common Community Physics Package: Fostering Collaborative Development in Physical Parameterizations and Suites
Authors: Bernardet Ligia , Bengtsson Lisa , Reinecke Patrick A. , Yang Fanglin , Zhang Man , Hall Kyle , Doyle James , Martini Matus , Firl Grant , Xue Lulin 
Published: June 2024

Abstract
The Common Community Physics Package (CCPP) is a state-of-the-art infrastructure designed to facilitate community-wide development of atmospheric physics parameterizations, support their interoperability among different modeling centers, and enable the transition of research to operations in NWP and climate modeling. The CCPP consists of two elements: the Physics (a repository of parameterizations) and the Framework (an infrastructure for interfacing the parameterizations with host models). The CCPP is a community resource: Its latest release has 23 primary parameterizations, which can be organized into six supported suites. It is distributed with a single-column model to facilitate physics development and experimentation. The Developmental Testbed Center provides support to users and developers. A key aspect of the CCPP is its interoperability, that is, its ability to be used by multiple host models. This enables synergistic collaboration among groups dispersed over various institutions and working on various models. In this article, we provide an overview of the CCPP and how it is being used in two leading modeling systems. The CCPP is part of the Unified Forecast System (UFS), is included in the NOAA operational Hurricane Analysis and Forecast System (HAFS) version 1, and is slated for use in all upcoming NOAA global and limited-area UFS applications for operations. Similarly, the CCPP has been integrated into the Navy Environmental Prediction System Using a Nonhydrostatic Engine (NEPTUNE) model and is undergoing testing for the upcoming transition to operations. These experiences make physics interoperability a reality and open the doors for much broader collaborative efforts on ESM development.
The Trauma Recovery Clinic: A Stepped Collaborative Care Model for Trauma Surgery Patients to Address Health Disparities
Authors: Conrad Erich J. , Rajo Erika M. , Barker Chikira , Beiter Kaylin , Hughes Jennifer B. , Stuart Sarah 
Published: June 2024

Background: The Trauma Recovery Clinic (TRC) was developed to meet the psychiatric, psychological, and psychosocial needs of traumatically injured patients following discharge from a level-I trauma center. The objective of this study is to demonstrate the efficacy of the TRC as an application of the stepped collaborative care model in order to address health disparities. Methods: Patients with a history of inpatient treatment for a physically traumatic injury at this level-I trauma center were approached and enrolled at initial TRC outpatient appointments. Data was collected, including the PTSD Checklist-Civilian Version (PCL-C), the Patient Health Questionnaire (PHQ-9), the Attitudes towards Guns scale, and the Youth Behavior Risk Survey (questions about weapon carrying practices). Results: A total of 80 patients were included in this study. Patients expressed several social determinants of health risk factors, with 60% of the sample reporting witnessing someone being wounded or killed. Results demonstrated a significant decrease in trauma symptoms (T24 = 3.33; P = .001, d = 0.67) and depressive symptoms (T24 = 2.23, P = .02, d = 0.45) by their 6th clinic visit. Additionally, patients reported significant improvements in role limitations due to emotional problems (T25 = 1.74; P = .04; d = 0.34) and social functioning (T25 = 2.23; P = .02; d = 0.43). Interestingly, patients who reported carrying a weapon in the last 30 days reported significantly higher trauma symptoms (T64 = 3.21, P = .002) and depressive symptoms (T64 = 2.77, P = .007). Discussion: This evaluation of services at the recently implemented Trauma Recovery Clinic demonstrated that the clinic is successfully treating individuals who have experienced traumatic injuries. More specifically, the clinic services are effectively engaging a vulnerable, hard-to-reach patient population.
The Use of a Just Noticeable Difference Approach to Improve Perceptual Acuity Ability in Male Runners
Authors: Krause Maressa Priscila , Haile Luke , Antonio Dayanne Sampaio , Peres Andre L. , Robertson Robert J. 
Published: June 2024

We were interested in micro-variations in an athlete’s psychophysical state that separate peak exertion from physiological collapse. Thus, we measured perceptual acuity in runners using a classic psychophysical approach, the just noticeable difference (JND) on two standard stimuli runs at treadmill speed corresponding to 70%VO2max and 80%VO2max. Thirty-four male runners ( M age = 35.26, SD = 7.33 years) first performed a maximal treadmill test to determine the speed of a standard exercise bout for the JND trials. The JND trials consisted of four 5-minute running bouts on a treadmill with 5-minute rests between bouts. For bouts 1 and 3, participants ran at the standard stimuli pace, but for bouts 2 and 4, they adjusted their speeds to achieve a level of exertion at a JND above/below the SS. They achieved differences in the final 30 seconds of the VO2 between each JND bout and the previous standard stimuli at just above (JND-A) and just below (JND-B) the JND perceived exertions. We used a Generalized Linear Model analysis to compare the JND-A and JND-B within and between ventilatory threshold groups (lower/higher) in absolute and relative VO2 and in terms of the total JND magnitude. The magnitude of JND-A was greater than that of JND-B at 70%VO2max and 80%VO2max in absolute units (70%VO2 Δ = 2.62; SE = 0.37; p < .001; 80%VO2 Δ = 1.67; SE = 0.44; p = .002) and in relative units (70%VO2max Δ = 4.70; SE = 0.66; p < .001; 80%VO2max Δ = 2.96; SE = 0.80; p = .002). The total magnitude was greater in the 70%VO2max trial than 80%VO2max in absolute units (70%VO2 M = 3.78, SE = 0.31 mL·kg−1·min−1; 80%VO2 M = 2.62, SE = 0.37 mL·kg−1·min−1; p = .020) and in relative units (70%VO2max M = 6.57, SE = 0.53%VO2max; 80%VO2max M = 4.71, SE = 0.64%VO2max; p = .030). The JND range narrowed when physiologic demand increased, for both physical (speed) and psychological (RPE) variables.
Social connection and self-neglect: A case for broader exploration
Authors: Burnett Jason , Hoyumpa Gabrielle M. , Beauchamp Jennifer E. S. , Hernandez-Tejada Melba A. , Acierno Ronald , Perissinotto Carla 
Published: June 2024

Objective Self-neglect (SN) is the most common report to Adult Protective Services (APS) and is associated with significant morbidity and mortality risks for older adults. Lack of instrumental support is a well-evidenced etiologic factor in the development and continuation of SN, but little is known about other modifiable social connection characteristics. The social connection framework provides evidence-based characteristics across structure, function, and quality missing from SN studies that could be identified if explored. These factors could provide prevention and intervention targets related to poor health. Methods A narrative case study is presented using quantitative and qualitative data to explore social connection across structure, function, and quality in the context of SN. Results The findings highlight the complexity of social connection that may be observed in SN cases reported to APS. Strategic utilization of direct and indirect social interventions to support social connection in this case are presented. Conclusion The results from this case give rise to considerations that may be generalizable to other SN cases. Recommendations for future research on social connection in this population are provided.
Percutaneous coronary intervention in patients with hypertrophic cardiomyopathy and coronary artery disease
Authors: Zhang Jinwei , Cui Hao , Sun Peng , He Jiqiang , Shi Shutian , Kang Yunpeng , Yu Jianbo , Ren Changwei 
Published: June 2024

Background Coronary artery disease and left ventricular outflow tract obstruction may overlap in symptoms in patients with hypertrophic cardiomyopathy. It has not been clear if coronary revascularization relieves exertional symptoms in patients with hypertrophic cardiomyopathy. Methods We reviewed 156 patients with hypertrophic cardiomyopathy who underwent percutaneous coronary intervention at Anzhen Hospital from 2009 to 2019. Improvement in symptoms after the percutaneous coronary intervention was investigated. Results The mean age was 60.8 ± 9.8 years, and 116 (74.4%) were men. The main symptoms of the patients were chest tightness in 115 (73.7%), chest pain in 88 (56.4%), dyspnea in 50 (32.1%), palpitation in 22 (14.1%), and presyncope/syncope in 12 (7.7%). At rest, the systolic anterior motion of the mitral valve was observed in only 36 patients. Among the 156 patients, 64 had single-vessel disease, 46 had two-vessel diseases, and the other 46 had three-vessel diseases. There was no early mortality in the present cohort. After the coronary intervention, there were significant improvements in symptoms including chest tightness (6.4%), chest pain (1.3%), dyspnea (2.6%), and palpitation (8.3%). In 93 patients with follow-up data, the overall survival was 77% at 10 years and the survival free from intervention was 60% at 10 years. Conclusions In patients with hypertrophic cardiomyopathy, coronary artery disease can be an important cause of symptoms and should be screened. Percutaneous coronary intervention is safe and effective for coronary revascularization. Cardiac symptoms can be significantly relieved and long-term outcomes are favorable.
Obtaining cellulose nanocrystals by acid hydrolysis procedure; and their use as reinforcement in polylactide biocomposites
Authors: Sarı Burcu , Kaynak Cevdet 
Published: June 2024

In the first step of this study, purpose was to obtain and characterize cellulose nanocrystal (CNC) particles by applying sulfuric acid hydrolysis method to the starting material of microcrystalline cellulose (MCC) fibrils. After obtaining CNC particles via acid hydrolysis procedure, various analyses (SEM, DLS, FTIR, XRD, TGA) conducted revealed that average size of round shaped CNC particles was 38 nm with −30.4 mV Zeta potential value. They had monoclinic Cellulose-I crystal structure with Crystallinity Index of 80.6% and Crystallite Size of 3.39 nm. Their maximum thermal degradation temperature was 307°C with 23 wt% residue at 800°C. In the second step, the main aim was to investigate contribution of these obtained CNC particles when they were used as nano-reinforcement in polylactide (PLA) matrix biocomposites produced by industrially compatible melt mixing and shaping techniques. Mechanical tests revealed that when only 1 wt% CNC particles were incorporated into PLA matrix, increases in flexural strength and modulus were 29% and 51%; while increases in K IC and G IC fracture toughness values were 42% and 105%, respectively. Because, high degree of hydroxyl groups and presence of sulfate half-ester groups on the surfaces of CNC particles improved the interfacial interactions between the matrix and nano-reinforcement phase, leading to efficiency in strengthening and toughening mechanisms.
Efficacy of adding infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) to adductor canal block and local infiltration analgesia in total knee arthroplasty: A retrospective cohort study
Authors: Zhao Dongmei , Li Pengcheng 
Published: June 2024

Objective Local infiltration analgesia (LIA), adductor canal block (ACB), and infiltration between the popliteal artery and the capsule of the posterior knee (IPACK) are popular multimodal analgesia techniques used during total knee arthroplasty (TKA). This study aimed to explore the efficacy of adding the IPACK technique to ACB and LIA in patients undergoing TKA. Methods In this retrospective cohort study, patients who underwent primary unilateral TKA were divided into two groups based on their date of admission. Sixty-three patients underwent IPACK, ACB and LIA (IPACK group) during surgery, while 60 patients underwent ACB and LIA (control group). The primary outcome was the postoperative administration of morphine hydrochloride as a rescue analgesic. Secondary outcomes included time to first rescue analgesia, postoperative pain assessed using the visual analog scale (VAS), functional recovery assessed by knee range of motion and ambulation distance, time until hospital discharge, and complication rates. Results The two groups were similar in average postoperative 0-to-24-h morphine consumption (11.8 mg for the control group vs 12.7 mg for the IPACK group, p = .428) and average total morphine consumption (18.2 mg vs 18.0 mg, p = .983) during hospitalization. There were also no significant differences in the secondary outcomes. Conclusions The addition of IPACK to ACB and LIA did not provide any clinical analgesic benefits. Orthopedic surgeons and anesthesiologists are justified in using ACB and LIA without IPACK for TKA.
Feasibility and Effectiveness of Virtual Group Advance Care Planning Visits During the COVID-19 Pandemic
Authors: Yourman Lindsey , Pollner Alina , Khatibi Jasmine , Ramos Vanessa , Melkote Vaishnavi , O’Gorman Aoibhin , Begler Erika , Lum Hillary D. 
Published: June 2024

Background The COVID-19 pandemic necessitated the transition from in person to virtual advance care planning (ACP) engagement efforts. This pilot initiative evaluated virtual group visits (GVs) and in-person GVs for ACP to determine their feasibility and effectiveness. Methods Participants included patients in a Geriatric Medicine clinic who were referred by their primary care physician to an ACP GVs intervention. The ACP GVs had 2 sessions, led by clinicians with ACP expertise who facilitated a discussion on patients’ values, goals, and preferences. Participants were provided with technical assistance to support use of the virtual platform. Evaluation included an ACP readiness survey, post-session feedback, GV observations, and electronic health record review at baseline and a 6 month follow-up for goals of care documentation and advance directives. Results Seventy patients attended 46 ACP GVs from August 2019 to February 2022, including 16 in-person GVs and 54 virtual GVs. At a 6 month follow-up, for virtual GVs participants (n = 54), goals of care documentation increased from 31% to 93%, and advance directives increased from 22% to 30%. For in-person GVs participants (n = 16), goals of care documentation increased from 25% to 100%, and advance directives increased from 69% to 75%. All surveyed patients in both formats would recommend ACP GVs. Conclusion ACP GVs are feasible and effective for supporting ACP, demonstrating an increase in both goals of care conversations and advance directives completion.
How to Engage Older LGBTQIA+ Patients: Lessons Learned From Mayo Clinic Connect, a 100,000+-Participant Social Media Platform
Authors: Fee-Schroeder Kelli , Young Colleen , Chedid Victor , Jatoi Aminah , Cathcart-Rake Elizabeth 
Published: June 2024

Background Older LGBTQIA+ patients face discrimination in healthcare and therefore are sometimes reluctant to engage and interact with healthcare providers. This report explores whether a large medically-based internet platform can be used to engage these patients and describes preferable methods for doing so. Methods This study used Mayo Clinic Connect, a continuously monitored, internet-based social media platform of 100,000-plus users. Participants completed a brief on-line survey to ensure their study eligibility. No patient-identifying data was asked. Participants then were to call in by phone during specified day time hours for a 45-minute qualitative interview. Alternatively, as a second subsequent option, they were to complete an on-line typed response to 4 questions about their health and healthcare. No temporal overlap occurred between the availability of the phone interview option and the typed-in response option. Results For the phone interviews, 17 of 64 individuals were deemed eligible, but no individual called in to be interviewed. In contrast, for the typed-in response option, 20 of 37 individuals were eligible and provided comments. Conclusion A large medically-based internet platform can be used to engage older LGBTQIA+ patients, but the use of typed-in comments appears more successful, presumably because of greater anonymity and convenience.
An Integrative Review of the Feasibility and Effects of the Use of Location-Tracking Devices by Persons Living With Cognitive Impairment
Authors: Kim Jayeong , Hwang Mina , Hwang Yeji 
Published: June 2024

Objectives This study aimed to examine the effects of location-tracking devices on persons living with cognitive impairment, investigate facilitators of and barriers to using the devices, and provide future directions for the use of the devices. Methods An integrative review was conducted using 5 databases: PubMed, Embase, Web of Science, CINAHL, and Scopus. From the 1429 initially identified studies, 10 were included in the review. Results Location-tracking devices benefited persons living with cognitive impairment and their informal caregivers. The devices brought more independence to persons living with cognitive impairment, allowing them to go outside and feel safer there. Furthermore, the devices reduced the caregivers’ worries about their loved ones being lost. Conclusions Location-tracking devices have the potential to increase independence in persons living with cognitive impairment and to decrease psychological stress in informal caregivers. In the future, ways to minimize the barriers to using location-tracking devices need to be determined.
Learning curve in tibial and pedal bypass with autologous vein graft
Authors: Kobayashi Taira , Hamamoto Masaki , Okazaki Takanobu , Okusako Ryo , Takahashi Shinya 
Published: June 2024

Objectives The 2019 Global Vascular Guidelines recommended open bypass for patients at average risk with greater limb severity and anatomical complexity. However, the outcomes of tibial and pedal bypass (TPB) are inferior to those of above-the-knee surgical revascularization. This may be due to the technical difficulty and need for development of skills to perform TPB. However, there is a limited knowledge on the learning curve in TPB. Thus, the aim of the study is to assess this learning curve in a single-center retrospective analysis. Methods Cases treated with TPB with an autologous vein conduit in patients with chronic limb-threatening ischemia (CLTI) at a Japanese single center from 2009 to 2022 were analyzed retrospectively. The primary endpoint was the learning curve for TPB. Results The study included 449 TPB procedures conducted by a single main surgeon in patients with CLTI (median age, 75 years; 309 males; diabetes mellitus, 73%; end stage renal failure with hemodialysis, 44%). The operative time decreased significantly as the number of cases accumulated ( p < .001). Using the cumulative sum (CUSUM) operative time, the learning curve was estimated to be phase 1 (initial learning curve) for 134 cases (1–134); phase 2 (competent period) for 179 cases (135–313); and phase 3 (mastery and challenging period) for 136 cases (314–449). The mean follow-up period was 34 ± 31 months. The 1- and 3-year limb salvage rates of 97% and 96% in phase 3 were significantly higher than those in phases 1 and 2 ( p < .001, p = .029). Major adverse limb events (MALE) occurred in 117 (26%) patients, and the 1- and 3-year MALE rates of 10% and 17% in phase 3 were significantly lower than those in phases 1 and 2 ( p < .001, p = .009). Conclusions In the study, vascular surgeon required a learning curve of 134 TPB cases to Overcoming the learning curve for bypass was associated with improvement of medium-term outcomes for limb salvage and freedom from MALE.
Immunodeficiencies and CFTR dysfunction: results from a systematic screening in a cohort of adults with cystic fibrosis and CFTR-related disorders
Authors: Amati Francesco , Leonardi Gloria , Contarini Martina , Morlacchi Letizia Corinna , Stainer Anna , Pizzamiglio Giovanna , Aliberti Stefano , Blasi Francesco , Gramegna Andrea 
Published: June 2024

Background: Immunodeficiencies (IDs) are conditions caused by immune system dysfunctions which predispose to chronic infections. Cystic fibrosis (CF) patients are characterized by the presence of bronchiectasis filled with hyper-viscous secretions that constitute the ideal environment for infections. Although CF and IDs might share similarities in the pathophysiological mechanism of bronchiectasis development, they each offer different treatment options. We hypothesize that the introduction of a bundle of tests would increase the number of ID diagnoses among adults with Cystic Fibrosis Transmembrane conductance Regulator (CFTR) dysfunction. Objectives: The primary objectives of this study were (1) assessing the prevalence of IDs in CF and (2) defining clinical characteristics of adults with both CF and IDs. The secondary objectives were: (1) assessing the prevalence of IDs in CFTR-Related Disorder (CFTR-RD) patients; (2) comparing the prevalence of IDs in CF and CFTR-RD; (3) comparing the prevalence of treatable IDs in CF and CFTR-RD. Design: We conducted an observational, prospective, consecutive study on a cohort of 190 adult patients affected by CF or CFTR-RD. Methods: Blood samples underwent a standardized immunological screening, including complete white blood count, IgG, IgA, IgM, IgG subclasses, total IgE, lymphocyte subsets, and HIV test. Comprehensive clinical history was assessed to identify risk factors for secondary IDs. Results: We identify a high prevalence of immunodeficiencies among the entire cohort: 34 (20.1%) CF patients and 10 (47.6%) CFTR-RD patients are diagnosed with IDs via a blood screening. No statistically significant difference in terms of clinical characteristics was found between immunocompromised and immunocompetent CF patients. Conclusion: We identify a high prevalence of immunodeficiencies in both CF and CFTR-RD.