bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implant treatment in patients with oral lichen planus: a prospective‐controlled study
Authors: Hernández Gonzalo , Lopez‐Pintor Rosa María , Arriba Lorenzo , Torres Jesús , de Vicente Juan Carlos 
Published: April 2011

AbstractObjectives:The main aim of this prospective‐controlled study was to evaluate the implant survival rate in patients diagnosed with oral lichen planus (OLP). The secondary goals were to analyze the presence of implant‐ and patient‐dependent variables.Material and methods:Two groups, including 18 patients diagnosed with OLP and 18 controls, received 56 and 62 implants during the years 2003–2008. Pain and wound healing were evaluated after the procedure. After a mean follow‐up of 53.5 and 52.3 months, clinical and radiographic assessments were used to evaluate implant survival and patient‐ and implant‐dependent parameters.Results:The implant survival rate was 100% for the OLP group. Immediate postsurgical complications were similar in both groups. Peri‐implant mucositis (PIM) was detected in 44.6% of the implants and 66.6% of the patients with OLP. The presence of desquamative gingivitis (DG) was associated with a higher rate of PIM on those implants of the OLP group (P=0.004). Peri‐implantitis (PI) appeared in 10.7% of the implants and 27.7% of the patients with OLP (P=NS).Conclusion:Despite the limitations of the small sample size, it seems that lichen planus is not a prominent local player in the genesis of implant failure. Patients with DG should be carefully examined during follow‐up care.
In vivo skin measurements with a novel probe head for simultaneous skin impedance and near‐infrared spectroscopy
Authors: Bodén Ida , Larsson William , Nilsson David , Forssell Erik , Naredi Peter , Lindholm‐Sethson Britta 
Published: April 2011

Background/purpose: Near‐infrared (NIR) spectroscopy and skin impedance (IMP) measurements are useful techniques for objective diagnostics of various skin diseases. Here, we present a combined probe head for simultaneous, time‐saving NIR spectroscopy and skin impedance measurements. The probe also ensures that both measurements are performed under equal conditions and at the same skin location.Methods: Finite element method simulations were performed for evaluation of the impedance. In vivo skin measurements were performed and combined NIR and impedance spectra were analysed by means of multivariate methods with respect to body location, age and gender. The classification rate was determined by a planar discriminant analysis. Reproducibility was investigated by calculation of scatter values and statistical significance between overlapping groups was assessed by the calculation of intra‐model distances, q.Results: The novel probe yielded rapid reproducible results and was easy to manage. Significant differences between skin locations and to a lesser extent age groups and gender were demonstrated.Conclusion: With the novel probe, statistically significant differences between overlapping classes in score plots can be confirmed by calculating intra‐model distances. The influence of molecular differences in the skin at different body locations is larger than the influence of gender or age and therefore relevant reference measurements are discussed.
IL‐8 and MCP‐1 induced by excessive orthodontic force mediates odontoclastogenesis in periodontal tissues
Authors: Asano M , Yamaguchi M , Nakajima R , Fujita S , Utsunomiya T , Yamamoto H , Kasai K 
Published: April 2011

Oral Diseases (2011) 17, 489–498Objective:  The aim of this study was to investigate how interleukin (IL)‐8 (cytokine‐induced neutrophil chemoattractant; CINC‐1) and monocyte chemotactic protein (MCP)‐1/CCL2 contribute to root resorption during orthodontic tooth movement.Materials and methods:  Forty 6‐week‐old male Wistar rats were subjected to orthodontic force of 10 or 50 g to induce a mesially tipping movement of the upper first molars for 7 days. We determined the expressions of CINC‐1, CXCR2, and MCP‐1 proteins in root resorption area using immunohistochemistry. Furthermore, we investigated the effects of compression forces (CF) on IL‐8 and MCP‐1 production by human periodontal ligament (hPDL) cells. We observed an effect of chemokine treatment on rat odonto/osteoclasts in dentin slices that recapitulated root resorption.Results:  The immunoreactivity for CINC‐1/CXCR2 and MCP‐1 was detected in odontoclasts and PDL fibroblasts by the orthodontic force of 50 g on day 7. CF increased the secretion and the expression of mRNA of IL‐8 and MCP‐1 from PDL cells in a magnitude‐dependent manner. Moreover, CINC‐1 and MCP‐1 stimulated osteoclastogenesis from rat osteoclast precursor cells.Conclusion:  IL‐8 (CINC‐1) and MCP‐1 may therefore facilitate the process of root resorption because of excessive orthodontic force.
Treating bipolar depression – antidepressants and alternatives: a critical review of the literature
Authors: Tundo Antonio , Cavalieri Paola , Navari Serena , Marchetti Fulvia 
Published: April 2011

Objective: Although depressive symptoms are preponderant in the course of bipolar (BP) disorders, the treatment of BP depression remains a controversial issue with different clinical approaches available. This review addresses the issues of whether antidepressants (ADs) are effective in treating acute and long-term BP depression, risks linked to ADs and what alternatives to ADs are available.Methods: We searched the MEDLINE databases using the following syntax: [bipolar depression AND unipolar depression AND (antidepressants OR anticonvulsants OR lithium OR antipsychotics OR dopamine-agonists OR psychoeducation OR psychotherapy OR electroconvulsive therapy OR transcranial magnetic stimulation)]. The search included studies published up to 31 May 2009 and conducted on adults.Results: In the acute treatment of BP depression ADs are effective with no differences among drug classes. However, neither the switch into (hypo)mania induction rate nor the suicide risk linked to AD use are definitely established. The effectiveness of long-term AD use is limited to highly selected samples of patients with positive acute response. The risk of long-term ADs causing cycle acceleration and rapid cycling induction concerns a subpopulation of patients. Valid alternatives to ADs in treating acute BP depression are quetiapine, an olanzapine–fluoxetine combination, and electroconvulsive therapy for more severe patients. Lamotrigine is effective and safe in preventing depressive relapses. Psychotherapy and psychoeducation represent effective adjunctive treatments.Conclusion: In the treatment of BP depression there is not a specific effective treatment for all the patients. Interventions should therefore be personalised and the scientific evidence should be adapted to each patient's clinical features.
The Female Sexual Function Index (FSFI): Development of a Japanese Version
Authors: Takahashi Miyako , Inokuchi Tamaki , Watanabe Chie , Saito Tami , Kai Ichiro 
Published: April 2011

ABSTRACT

Introduction
A valid and reliable self-administered scale to measure multidimensional aspects of female sexual function is needed in Japan, as sexual dysfunction is quite common in Japanese women.

Aim
The aim of this paper is to develop a Japanese translation of the Female Sexual Function Index (FSFI-J), 3-month version, and to measure its psychometric reliability and validity.

Methods
Following a language validation process and pilot tests, we modified the scale by adding some instructions and answer options. A cross-sectional survey to examine psychometric reliability and validity of FSFI-J was conducted with 126 healthy Japanese women in partnered relationships. Reliability studies on test–retest and on internal consistency were conducted using the intraclass correlation coefficient (ICC) and Cronbach's α coefficient, respectively. A validity study was conducted on aspects of face, construct, concurrent, and discriminant validity.

Main Outcome Measures
The main outcome is the psychometric reliability and validity of FSFI-J.

Results
FSFI-J showed high test–retest reliability (ICC &gt; 0.78) and high internal consistency (Cronbach's α &gt; 0.84). In terms of face validity, FSFI-J was found to be understandable and can adequately measure various aspects of female sexual function. Regarding construct validity, exploratory factor analysis of FSFI-J supported a five-factor solution, consisting of desire/arousal, lubrication, orgasm, satisfaction, and pain. This domain structure was identical to that of the original FSFI. Regarding concurrent validity, FSFI-J total score and domain scores showed significant correlations (Pearson's r = −0.613 for total score) with the sexual function domain of the perimenopausal subjective symptom inventory and overall sexual satisfaction as measured by a visual analog scale (Pearson's r = 0.387). For discriminant validity, the regular menstruation group showed significantly higher FSFI-J scores than the menopause group in the total score and all subdomain scores except sexual satisfaction.

Conclusions
The FSFI-J is a valid and reliable instrument to measure multidimensional aspects of sexual function in healthy Japanese women who are in partnered relationships.
Limitations of the MRL mouse as a model for cardiac regeneration
Authors: Moseley Fleur L , Faircloth Matthew E , Lockwood Wendy , Marber Michael S , Bicknell Katrina A , Valasek Petr , Brooks Gavin 
Published: April 2011

Abstract

Objective
Myocardial repair following injury in mammals is restricted such that damaged areas are replaced by scar tissue, impairing cardiac function. MRL mice exhibit exceptional regenerative healing in an ear punch wound model. Some myocardial repair with restoration of heart function has also been reported following cryoinjury. Increased cardiomyocyte proliferation and a foetal liver stem cell population were implicated. We investigated molecular mechanisms facilitating myocardial repair in MRL mice to identify potential therapeutic targets in non-regenerative species.

Methods
Expressions of specific cell-cycle regulators that might account for regeneration (CDKs 1, 2, 4 and 6; cyclins A, E, D1 and B1; p21, p27 and E2F5) were compared by immunoblotting in MRL and control C57BL/6 ventricles during development. Flow cytometry was used to investigate stem cell populations in livers from foetal mice, and infarct sizes were compared in coronary artery-ligated and sham-treated MRL and C57BL/6 adult mice.

Key findings
No differences in the expressions of cell cycle regulators were observed between the two strains. Expressions of CD34+Sca1+ckit-, CD34+Sca1+ckit+ and CD34+Sca1-ckit+ increased in livers from C57BL/6 vs MRL mice. No differences were observed in infarct sizes, levels of fibrosis, Ki67 staining or cardiac function between MRL and C57BL/6 mice.

Conclusions
No intrinsic differences were observed in cell cycle control molecules or stem cell populations between MRL and control C57BL mouse hearts. Pathophysiologically relevant ischaemic injury is not repaired more efficiently in MRL myocardium, questioning the use of the MRL mouse as a reliable model for cardiac regeneration in response to pathophysiologically relevant forms of injury.
Treatment experience of people with obstructive sleep apnoea seeking continuous positive airways pressure device provision through community pharmacies – a role for pharmacists?
Authors: Shoukry Grace , Wong Keith , Bartlett Delwyn , Saini Bandana 
Published: April 2011

Abstract

Objectives
This study aimed to explore the unique experiences of people with obstructive sleep apnoea (OSA) who source their treatment through community pharmacies.

Methods
A qualitative study employing the phenomenological approach was used. In-depth semi-structured interviews with a purposive convenience sample of 20 participants were conducted. Twenty participants were recruited from community pharmacies offering continuous positive airways pressure (CPAP) device provision and a teaching hospital in Sydney, Australia. Interviews were digitally recorded and transcribed verbatim, coded using Nvivo8 software and analysed based on the ‘framework’ method.

Key findings
The quality and delivery of information at diagnosis was reported to have been inappropriate for participants' personal needs. Many barriers emerged in regards to CPAP use, consistent with current literature. Participants' self-reported individual styles, coping practices and health beliefs appeared to be the most influential factors in CPAP uptake and adherence, regardless of mechanical advancements and environmental support. High satisfaction was expressed with CPAP obtainment from pharmacy services listing convenience and good service as notable characteristics.

Conclusions
Community pharmacies have the potential to increase OSA awareness and improve optimal usage of CPAP. Psychosocial based models of adherence intervention could potentially be implemented through CPAP providers, including the community pharmacy, to address some of these factors which impede CPAP adherence.
An exploration of competitiveness and caring in relation to psychopathology
Authors: McEwan Kirsten , Gilbert Paul , Duarte Joana 
Published: April 2011

Objectives. Social mentality theory outlines how specialist systems have evolved to facilitate different types of social behaviour such as caring for offspring, forming alliances, and competing for resources. This research explored how different types of self‐experience are linked to the different social mentalities of competitive social ranking (focusing on gaining and defending one's social position/status/rank) in contrast to caring (being helpful to others). Perceived low social rank (with feelings of being inferior and unfavourable social comparison, SC) has been linked to depression, but a caring sense of self has less so. We hypothesized therefore that depression, in both clinical and non‐clinical populations, would be primarily linked to competitive and rank focused sense of self rather than a caring sense of self.Method. Students (N= 312) and patients with depression (N= 48) completed self‐report scales measuring: self‐experience related to competitiveness and caring; social rank; social safeness; and depression, anxiety, and stress.Results. The data suggest that in students, and particularly in patients, competitiveness (and feeling unsuccessful in competing for resources) is strongly associated with depression. Although caring shares a small correlation with depression in students, and with depression, anxiety, and stress in patients, when controlling for the rank variable of submissive behaviour this relationship ceases to be significant. Submissive behaviour was found to be a full mediator between caring and depression. We also found that how safe and comfortable one feels in one's social relationships (social safeness), was a full mediator between competitiveness and depression. So, it is the feeling of being unable to compete where one does not feel secure in one's social environment that is particularly linked to depression.Conclusion. The results of this study suggest that self‐experience is complex and multifaceted and is linked to different social roles that are socially contextualized. In addition, perceived low social rank and perceived failures in being able to ‘attract’ others and compete for social resources, are strongly linked to depression, whereas experiencing oneself as caring and helpful is not when submissiveness is controlled for.
Landing frequencies and types of landings in sub-elite male volleyball players
Authors: van Ark M , Zwerver J , Pepping G J 
Published: April 2011

BackgroundLandings seem to be one of the important factors in the multi-factorial aetiology of patellar tendinopathy among jumping athletes.ObjectiveThe aim of the current study was to investigate the frequencies and types of landings in sub-elite male volleyball players in both matches and training sessions.DesignProspective cohort study.SettingAll landings of players of a Dutch first division volleyball team were analysed during 2 weeks. Five training sessions and two matches took place in this period.ParticipantsPlayers of a sub-elite male volleyball team (n=12).Intervention and main outcome measurementsEvent (match/training session), landing foot (left/right/both), player position and action for which the jump was performed were recorded for every jump. A repeated measures analysis of variance was performed to test for possible effects of the variables event (within-factor), function (between-factor) and landing foot (within-factor) on mean number of landings per person.Results7944 landings were evaluated, the number of landings was higher during training sessions than during matches (ratio 5.5:1). 22% of the landings occurred on the left foot, 15% on the right foot and 63% on both feet. Jumps were performed for usual actions like a spike, block or set-up. The players landed significantly more on both feet than on their left or right foot. Setters landed significantly more on both feet than players with other functions and during training sessions landings occurred more on both feet than during matches.ConclusionsThis study showed that far more landings were performed during training sessions compared to matches. Most effects of prevention programs can thus be expected from interventions on landing type and frequency during training sessions. In this way the development of overload injuries like patellar tendinopathy might be prevented.
Effect of altitude training on the renin-angiotensin-aldosterone system and blood pressure in women
Authors: Cruz-Márquez J C , Cruz-Campos J C , Cruz-Campos A , Cueto-Martín MªB , García-Jiménez Mª , Campos-Blasco MªT 
Published: April 2011

BackgroundAltitude training produces advantages over sea level training, but athletes require acclimatization to avoid discomfort or mountain sickness, in which the blood pressure control is essential.ObjectiveTo investigate the influence of moderate altitude on blood pressure and renin-angiotensin-aldosterone systems in a women's volleyball team (Honor Division – Spain).DesignWe assessed 14 elite female volleyball players: 2 weeks under normoxia conditions (640 m above sea level), 2 weeks under relative hypoxia (2450 m, at the High Performance Centre of Sierra Nevada, Granada, Spain) and two final weeks back to normoxia.Setting and participants14 women (mean age 23±2.8 years; height: 184.9±6.9 cm; weight: 73.1±6.2 kg). All players who started the study completed it. None of the participants reported ingesting contraceptives or hormonal treatments.InterventionsThe volleyball players trained twice/day (3 h/session). The blood pressure was measured at rest in the morning, during and after physical exercise (both in the morning and in the afternoon season), as well as in urine/24 h the renin, angiotensin and aldosterone, renal water excretion and urinary volume every 5 days.Independent variable: Altitude.Dependent variables: Renin, angiotensin, aldosterone 24/h urinary levels; rest, pre and posttraining blood pressure.ResultsThe aldosterone levels decreased in the first hypoxic week (157.09 pg/ml; p<0.05 respect to level), as well as renin levels (12.82 pg/ml p<0.05 respect to level). There was an increase in renal water excretion (25 701.36 ml/day with a p<0.05). The diastolic blood pressure posttraining showed changes between the hypoxia and normoxia (69.72±12.3 vs 73.45±14.9 mm Hg p<0.05).ConclusionsRenin is reduced under hypoxia. Post-exercise diastolic blood pressure changes significantly at altitude with less venous return and may explain symptoms of mountain sickness.
Assessment of elite-level volleyball players' performance and fitness based on biometric data
Authors: Miyamoto D , Arima S , Ogiuchi T , Netsu M , Kanari S , Yakama K , Hamano I 
Published: April 2011

BackgroundImprovement sought in the performance of a professional volleyball team, eighth in Japanese Premiere Volleyball League 2009-Season, based on collection and analysis of biometric data.ObjectivePhysical performance and biometric data were collected from one team of the Japanese Premiere Volleyball League (CT) and the Japanese National Team (NT). The aim is to compare the fitness of CT to NT and analyze differences in athletes of high and low performance.DesignMeasure values in 10 physical performance tests and body-composition.SettingThe study was conducted in the regular training facility of CT team. Photo-detector and yardstick were used for measurements.Participants18 healthy male players on the active roster of CT team were examined. The control consisted of 21 members of NT.InterventionMeasurements for CT were taken during the 2010 off-season, with NT taken during the same period 2009. The 10 performance tests are: 20 m dash, pro agility, T test, vertical jump, medicine-ball throw, standing triple jump, standing triple long jump, block jump, sit-up, and endurance test. Body-composition parameters are age, height, weight, body mass index, standing reach, vertical jump, and running vertical jump.Main outcome measurementsWe hypothesized NT would show higher numbers than CT in both power and speed tests. Significant difference was found only in the medicine-ball throw, while other tests did not reveal significant differences.ResultsNT had higher numbers in height, weight, and standing reach, recorded higher numbers in medicine-ball throw. CT produced higher numbers in vertical jump.ConclusionsSince NT displayed higher numbers in medicine-ball throw CT will be required to improve power in order to achieve similar performance. Results also show that NT has slightly higher values in pro agility. This suggests that CT, with their lower body composition figures, also needs to improve agility to perform at the same level as NT.
Play structure of top female volleyball players: explorative factorial approach
Authors: Nesic G , Sikimic M , Ilic V , Stojanovic T 
Published: April 2011

BackgroundVolleyball, as a sports game, requires from the players high level preparedness with respect to all the motor abilities, as well as an efficient execution of necessary technical and tactical game elements.ObjectiveThe aim of this research is to establish characteristics of the competitive activity structure in female volleyball at European Senior Championships in Bulgaria 2001, in Turkey 2003 and in Croatia 2005.Design, setting and methodsAn overall of 48 games of all three championships were analyzed. Comparative analysis of the latent competitive activity structure of female volleyball players was performed by factorial data analysis (factor rotation in Varimax solution).ResultsIn the latent space of competitive analysis, three independent factors were isolated, justifying 73.76% of overall system variance. Factor 1 (space-time factor) explains 36.12% of overall variance and is defined by the following manifest variables: jumps (0.934), active (0.921) and passive (0.906) time of the game and strikes at ball (0.893). Factor 2 (situational precision) explains 21.46% of all variance and is defined by the following manifest variables: efficiency coefficient (KE) of serve receiving (0.940), followed by KE of ball raising for attack (0.829), and the lowest KE is manifested in field defence (0.815). Factor 3 (technical-tactical efficiency) in latent space of competitive activity explains 16.19% of all variance and is defined by the following manifest realization of technical-tactical elements (0.685), and the smallest and negative KE drops in the variables: KE of attack (0.819), serve KE (0.803), KE block (0.711), success in field defence (−0.558).ConclusionsAll the variables significantly contribute to defining of isolated factors, but the greatest contribution belongs to jumps, active and passive time of the game and strikes at the ball, which is logical, because these variables are constant during the entire game. Other variables, that is, isolated factors of situational precision and factors of technical-tactical efficiency, are expressed through them.