bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk-Adapted Breast Screening for Women at Low Predicted Risk of Breast Cancer: An Online Discrete Choice Experiment
Authors: Kelley Jones Charlotte , Scott Suzanne , Pashayan Nora , Morris Stephen , Okan Yasmina , Waller Jo 
Published: June 2024

Background A risk-stratified breast screening program could offer low-risk women less screening than is currently offered by the National Health Service. The acceptability of this approach may be enhanced if it corresponds to UK women’s screening preferences and values. Objectives To elicit and quantify preferences for low-risk screening options. Methods Women aged 40 to 70 y with no history of breast cancer took part in an online discrete choice experiment. We generated 32 hypothetical low-risk screening programs defined by 5 attributes (start age, end age, screening interval, risk of dying from breast cancer, and risk of overdiagnosis), the levels of which were systematically varied between the programs. Respondents were presented with 8 choice sets and asked to choose between 2 screening alternatives or no screening. Preference data were analyzed using conditional logit regression models. The relative importance of attributes and the mean predicted probability of choosing each program were estimated. Results Participants ( N = 502) preferred all screening programs over no screening. An older starting age of screening, younger end age of screening, longer intervals between screening, and increased risk of dying had a negative impact on support for screening programs ( P < 0.01). Although the risk of overdiagnosis was of low relative importance, a decreased risk of this harm had a small positive impact on screening choices. The mean predicted probabilities that risk-adapted screening programs would be supported relative to current guidelines were low (range, 0.18 to 0.52). Conclusions A deintensified screening pathway for women at low risk of breast cancer, especially one that recommends a later screening start age, would run counter to women’s breast screening preferences. Further research is needed to enhance the acceptability of offering less screening to those at low risk of breast cancer. Highlights Risk-based breast screening may involve the deintensification of screening for women at low risk of breast cancer. Low-risk screening pathways run counter to women’s screening preferences and values. Longer screening intervals may be preferable to a later start age. Work is needed to enhance the acceptability of a low-risk screening pathway.
Double-Bundle Medial Collateral Ligament Reconstruction Improves Anteromedial Rotatory Instability
Authors: Beel Wouter , Vivacqua Thiago , Willing Ryan , Getgood Alan 
Published: June 2024

Background: New techniques have been proposed to better address anteromedial rotatory instability in a medial collateral ligament (MCL)–injured knee that require an extra graft and more surgical implants, which might not be feasible in every clinical setting. Purpose: To investigate if improved resistance to anteromedial rotatory instability can be achieved by using a single-graft, double-bundle (DB) MCL reconstruction with a proximal fixation more anteriorly on the tibia, in comparison with the gold standard single-bundle (SB) MCL reconstruction. Study Design: Controlled laboratory study. Methods: Eight fresh-frozen human cadaveric knees were tested using a 6 degrees of freedom robotic simulator in intact knee, superficial MCL/deep MCL–deficient, and reconstruction states. Three different reconstructions were tested: DB MCL no proximal tibial fixation and DB and SB MCL reconstruction with proximal tibial fixation. Knee kinematics were recorded at 0°, 30°, 60°, and 90° of knee flexion for the following measurements: 8 N·m of valgus rotation (VR), 5 N·m of external tibial rotation, 5 N·m of internal tibial rotation, combined 89 N of anterior tibial translation and 5 N·m of external rotation for anteromedial rotation (AMR) and anteromedial translation (AMT). The differences between each state for every measurement were analyzed with VR and AMR/AMT as primary outcomes. Results: Cutting the superficial MCL/deep MCL increased VR and AMR/AMT in all knee positions except at 90° for VR ( P < .05). All reconstructions restored VR to the intact state except at 90° of knee flexion ( P < .05). The DB MCL no proximal tibial fixation reconstruction could not restore intact AMR/AMT kinematics in any knee position ( P < .05). Adding an anterior-based proximal tibial fixation restored intact AMR/AMT kinematics at ≥30° of knee flexion except at 90° for AMT ( P < .05). The SB MCL reconstruction could not restore intact AMR/AMT kinematics at 0° and 90° of knee flexion ( P < .05). Conclusion: In this in vitro cadaveric study, a DB MCL reconstruction with anteriorly placed proximal tibial fixation was able to control AMR and AMT better than the gold standard SB MCL reconstruction. Clinical Relevance: In patients with anteromedial rotatory instability and valgus instability, a DB MCL reconstruction may be superior to the SB MCL reconstruction, without causing extra surgical morbidity or additional costs.
Supratubercle Anterior Closing Wedge Osteotomy: No Changes in Patellar Height and Significant Decreases in Anterior Tibial Translation at 6 Months Postoperatively
Authors: Tollefson Luke V. , Kennedy Nicholas I. , Banovetz Mark T. , Homan Morgan D. , Engebretsen Lars , Moatshe Gilbert , Wulf Corey A. , Larson Christopher M. , LaPrade Robert F. 
Published: June 2024

Background: Because of the increased prevalence of revision anterior cruciate ligament (ACL) reconstruction, there has been a desire to understand the role of posterior tibial slope on increased anterior tibial translation and increased ACL graft forces. One potential concern in supratubercle anterior closing wedge proximal tibial osteotomy (ACW-PTO) for decreasing the posterior tibial slope is the risk of altering the patellar height. Purpose: To radiographically assess changes in (1) patellar height, (2) anterior tibial translation, and (3) posterior tibial slope after supratubercle ACW-PTO. Study Design: Case series; Level of evidence, 4. Methods: Patients who underwent supratubercle ACW-PTO by a single surgeon between July 2019 and June 2023 were included. Standardized lateral knee weightbearing radiographs to assess patellar height (via the Caton-Deschamps index), anterior tibial translation of the lateral tibial plateau relative to the lateral femoral condyle, and posterior tibial slope were obtained at 4 time points (preoperatively and 1 day, 3 months, and 6 months postoperatively). Paired t test was used to compare differences between preoperative, 1-day, and 3- and 6-month values for patellar height as measured using the Caton-Deschamps index and for posterior tibial slope. Paired t test was also used to compare differences in the preoperative and 6-month postoperative values for anterior tibial translation. Results: In 20 patients after ACW-PTO, the Caton-Deschamps index demonstrated a significant increase in patellar height on postoperative day 1 ( P < .001) but no significant differences at 3 ( P = .057) and 6 ( P = .176) months postoperatively. Anterior tibial translation on standing lateral knee radiographs was significantly decreased by a mean of 8.9 mm from preoperatively to 6 months postoperatively ( P < .001). Posterior tibial slope was significantly decreased by a mean of 11.2° from preoperatively to 6 months postoperatively ( P < .001). Conclusion: Supratubercle ACW-PTO performed for ACL reconstruction failure in the setting of an increased posterior tibial slope did not induce significant changes in patellar height postoperatively. Furthermore, after ACW-PTO, there was a significant decrease in anterior tibial translation and posterior tibial slope.
Location of Shoulder Glenoid Labral Tears: A Study of 1763 Consecutive Patients
Authors: Mohr Damaris , Nammour Michael A. , Marcaccio Stephen E. , Arner Justin W. , Bradley James P. 
Published: June 2024

Background: Anterior shoulder labral tearing has historically been considered the most common location of shoulder labral pathology. Recently, smaller studies have reported that posterior labral involvement may be more common than previously recognized. Purpose: To examine the location of surgically repaired labral tears by a single surgeon over a consecutive 23-year period. Study Design: Case series; Level of evidence, 4. Methods: A total of 1763 consecutive patients who underwent arthroscopic or open shoulder labral repair by a single seniorsports medicine fellowship–trained orthopaedic surgeon between April 2000 and April 2023 were retrospectively reviewed. Current Procedural Terminology codes were used to identify patients, which included 29806, 29807, 29822, and 29823. Exclusion criteria included isolated shoulder manipulation or glenohumeral joint or labral debridement that did not include repair. Intraoperative glenoid labral tears observed were categorized into 7 broad categories: (1) anterior labral tears, (2) posterior labral tears, (3) superior labral anterior posterior (SLAP) type II tears (A, B, or C), (4) SLAP type V tears, (5) SLAP type VIII tears, or (6) circumferential labral tears (combined SLAP, anterior, and posterior labral tear). Shoulders diagnosed with multiple tear patterns (ie, anterior and posterior) were also noted. Results: During the 23-year period, 1763 patients underwent arthroscopic or open labral repair; they included 1295 male and 468 female patients, ranging in age from 12 to 70 years, with a mean age of 23.2 years and median age of 19 years. Overall, 28.4% of tears involved the anterior labrum, 64.9% involved the posterior labrum, and 59.6% involved the superior labrum. Regarding isolated tears, 9.3% were isolated anterior labral tears, 19.7% were isolated posterior labral tears, 11.5% involved the anterior and posterior labrum, 22.2% were isolated superior (SLAP type II-IV) tears, 3.63% were isolated SLAP type V tears, 29.8% were isolated SLAP type VIII tears, and 4.1% were circumferential tears. Conclusion: Posterior shoulder labral tearing was more common than anterior tearing in a large consecutive series of 1763 patients who underwent surgical repair. This highlights the importance of posterior labral pathology, which sometimes may be overlooked because of more vague complaints, with pain and loss of function being the most common.
Perfusion increase in foot angiosomes: Comparison between direct and indirect revascularization of crural arteries
Authors: Venermo Maarit , Settembre Nicla 
Published: June 2024

Background and aims: In retrospective studies, wound healing and leg salvage have been better if revascularization is targeted to the crural artery supplying arterial flow to the wound angiosome. No data exist on how revascularization changes the blood flow in foot angiosomes. The aim of this study was to evaluate the change in perfusion after infrapopliteal artery revascularization in all foot angiosomes and to compare directly revascularized (DR) angiosomes to the indirectly revascularized (IR) angiosomes. Methods: In this prospective study, foot perfusion was measured with indocyanine green fluorescence imaging (ICG-FI) before and after either surgical or endovascular below-knee revascularization. According to angiograms, we divided the foot angiosomes into DR and IR angiosomes. Furthermore, in a subanalysis, the IR angiosomes were graded as IR_Coll+ angiosomes if there were strong collaterals arising from the artery which was revascularized, and as IR_Coll– angiosomes if strong collaterals were not seen. Results: A total of 72 feet (28 bypass, 44 endovascular revascularizations) and 282 angiosomes were analyzed. Surgical and endovascular revascularization increased perfusion significantly in both DR and IR angiosomes. After bypass surgery, the increase in DR angiosomes was 55 U and 53 U in IR angiosomes; there were no significant difference in the perfusion increase between IR and DR angiosomes. After endovascular revascularization, perfusion increased significantly more, 40 U, in DR angiosomes compared to 26 U in IR angiosomes (p < 0.05). In the subanalysis of IR angiosomes, perfusion increased significantly after surgical bypass regardless of whether strong collaterals were present or not. After endovascular revascularization, however, a significant perfusion increase was noted in the IR_Coll+ but not in the IR_Coll− subgroup. Conclusion: Open revascularization increased perfusion equally in DR and IR angiosomes, whereas endovascular revascularization increased perfusion significantly more in DR than in IR angiosomes. Strong collateral network may help increase perfusion in IR angiosomes.
Aeroacoustic source localization using the microphone array method with application to wind turbine noise
Authors: Xue Weicheng , Yang Bing 
Published: June 2024

The deconvolution DAMAS algorithm can effectively eliminate the misconceptions in the usually-used beamforming localization algorithm, allowing for a more accurate calculation of the source location as well as the intensity. When solving a linear system of equations, the DAMAS algorithm takes into account the mutual influence of different locations, reducing or even eliminating sidelobes and producing more accurate results. This work first introduces the principles of the DAMAS algorithm. Then it applies both the conventional beamforming algorithm and the DAMAS algorithm to simulate the localization of a single-frequency source from a 1.5 MW wind turbine, a complex line source with the text “UCAS” and a line source downstream of an airfoil trailing edge. Finally, the work presents experimental localization results of the source of a 1.5 MW wind turbine using both the conventional beamforming algorithm and the DAMAS algorithm.
The Utility of Expert-Rated and Self-Report Assessments of Youth Psychopathic Traits for Predicting Felony Recidivism Among Formerly Incarcerated Youth
Authors: Allen Corey H. , Maurer J. Michael , Gullapalli Aparna R. , Edwards Bethany G. , Aharoni Eyal , Anderson Nathaniel E. , Harenski Carla L. , Kiehl Kent A. 
Published: June 2024

Psychopathic traits assessed with expert-rated instruments are well-established predictors for both general and violent felony recidivism outcomes in adjudicated youth. However, it is not clear whether self-report assessments of psychopathic traits show similar predictive value. The current study evaluated both expert-rated (i.e., the Hare Psychopathy Checklist: Youth Version [PCL:YV]) and self-report measures (i.e., the Childhood Psychopathy Scale, Inventory of Callous Unemotional Traits, Antisocial Process Screening Device, and the Youth Psychopathic Traits Inventory) assessing youth psychopathic traits for predicting general and violent felony recidivism among formerly incarcerated high-risk male adolescents ( n = 275). Scores on both expert-rated and self-report instruments were significantly associated with a shorter time to felony rearrest into early adulthood (with an average follow-up window of 11 years). However, the expert-rated PCL:YV, but not self-report measures, provided significant utility for predicting violent felony arrest. These results suggest that in general, youth psychopathic traits, regardless of the specific instrument used, are predictors of general felony rearrest outcomes, while the expert-rated PCL:YV alone provides utility for predicting the most severe crimes (i.e., violent felonies). The strengths and limitations of the assessment modalities are discussed.
Time With Rapid Change of Glucose
Authors: Christensen Mia , Nørgaard Louise Jung , Bohl Mette , Bibby Bo Martin , Hansen Klavs Würgler 
Published: June 2024

Background: A variety of metrics are used to describe glycemic variation, some of which may be difficult to comprehend or require complex strategies for smoothing of the glucose curve. We aimed to describe a new metric named time with rapid change of glucose (TRC), which is presented as percentage of time, similar to time above range (TAR), time in range (TIR), and time below range (TBR). Method: We downloaded glucose data for 90 days from 159 persons with type 1 diabetes using the Abbott Freestyle Libre version 1. We defined TRC as the proportion of time (%) with an absolute rate of change of glucose > 1.5 mmol/L/15 minutes (1.8mg/dL/min) corresponding to a minimum rate of change for glucose in the 3.9-10.0 mmol/L (70-180 mg/dL) range within 1 hour. TRC is related to the other glucose variability metrics: CV within day (CVw) and mean amplitude of glycemic excursion (MAGE). Results: The more than 1.27 million glucose rates were t-location scale distributed with SD 0.91 mmol/L/15 min (1.1 mg/dL/15 min). The median TRC was 6.9% (IQR 4.5%-9.5%). The proportion of TRC with positive slope was 3.9% (2.6%-5.3%) and significantly higher than the proportion with negative slope 2.8% (1.5%-4.4%) P < .001. TRC correlated with CVw and MAGE (Spearman’s correlation coefficient .56 and .65, respectively, P < .001). Conclusion: TRC is proposed as an easily perceived metric to compare the performance of hybrid or fully automated closed-loop insulin delivery systems to obtain glucose homeostasis.
Diving Into the Health Problems of Competitive Divers: A Systematic Review of Injuries and Illnesses in Pre-elite and Elite Diving Athletes
Authors: Currie Benjamin M. , Drew Michael K. , Hetherington Michael , Waddington Gordon , Brown Nicholas A.T. , Toohey Liam A. 
Published: June 2024

Context: The Olympic sport of diving involves the competitive disciplines of 3 m springboard and 10 m platform. Although it is generally accepted that lumbar spine injuries are common in diving athletes, the existing literature of health problems in diving athletes remains scarce. Objective: To identify the incidence, prevalence, and type of health problems that occur in competitive diving athletes. Data Sources: Medline, EMBASE, SportsDiscus, PsycINFO, and Google Scholar. Study Selection: Studies written in English investigating elite or pre-elite competitive diving (springboard, platform) injuries and/or illnesses were eligible. Two independent reviewers screened for inclusion by title, abstract, and full text in accordance with the eligibility criteria. Study Design: Systematic review. Level of Evidence: Level 4. Data Extraction: Data extraction was completed by 1 author using a structured form. A second author then independently reviewed and verified the extracted data, any discrepancies were resolved through consensus. Results: The search identified 2554 potential articles, with 28 studies meeting eligibility criteria. The surveillance setting of most studies was restricted to competition-based events, with the reported injury incidence proportion ranging from 2.1% to 22.2%. The reported injury incidence rate ranged from 1.9 to 15.5 per 1000 athlete-exposures. Injuries to the shoulder, lower back/lumbar spine, trunk, and wrist/hand were reported most frequently. The prevalence of low back pain was reported as high as 89% (lifetime), 43.1% (period), and 37.3% (point). The illness incidence proportion ranged from 0.0% to 22.2%, with respiratory and gastrointestinal illness reported most frequently. Conclusion: Up to 1 in 5 diving athletes sustain an injury and/or illness during periods of competition. A reporting bias was observed, with most cohort studies limiting surveillance to short competition-based periods only. This limits the current understanding of the health problems experienced by diving athletes to competition periods only and requires expansion to whole-of-year surveillance.
Individualized predictions for clinical milestone in amyotrophic lateral sclerosis: A multialgorithmic approach
Authors: Oh Hyeon-Ji , Lee Won-Joon , Sung Jung-Joon , Hong Yoon-Ho ,   the Pooled Resource Open-Access ALS Clinical Trials Consortium
Published: June 2024

Objective The phenotypic heterogeneity and complex disease trajectory complicate the ability to predict specific clinical milestone for individual patients with amyotrophic lateral sclerosis (ALS). Here we developed individualized prediction models to estimate the time to the loss of autonomy in swallowing function. Methods Utilizing the Pooled Resource Open-Access ALS Clinical Trials (PRO-ACT) database, we built three models of distinct time-to-event prediction algorithms: accelerated failure time (AFT), cox proportional hazard (COX) and random survival forest (RSF) for an individualized risk assessment of the swallowing milestone. The target variable was defined as the time to a decline in the ALSFRS-R swallowing item score to 1 or below, indicating a need for supplementary tube feeding. Results Internal cross-validation revealed the median concordance index (C-index) of 0.851 (IQR, 0.842–0.859) for AFT, 0.850 (0.841–0.859) for COX and 0.846 (0.839–0.854) for RSF, and all models demonstrated good distributional calibration with predicted and observed event probabilities closely matched across different time intervals. For external validation with a registry dataset with characteristics different from PRO-ACT, the discriminative power was replicated with comparable C-indices for all models, whereas the calibration revealed a left-skewed distribution suggesting a bias towards overestimation of event probabilities in real-world data. While all models were effective at stratifying patients, the results of RSF model, unlike AFT and COX, did not match well with the KM curves of the corresponding risk groups, supporting the importance of nuanced understanding of data structure and algorithmic properties. Conclusion Our models are implemented into a web application which could be applied to individualized counselling, management and clinical trial design for gastrostomy intervention. Further studies for model optimization will advance personalized care in patients with ALS.
The Experiences of International Researchers in Japanese Companies: A Graduate Capital Perspective
Authors: Li (李明) Ming , Huang (黄福涛) Futao 
Published: June 2024

Purpose This study investigates the motivations, contributions, and challenges faced by international researchers employed at Japanese companies. It utilizes Tomlinson's Graduate Capital Model to gain insight into their experiences. Design/Approach/Methods This study employs Tomlinson's Graduate Capital Model as an analytical framework to analyze data from semi-structured interviews with 15 international researchers, focusing on their experiences and perspectives. Findings The study indicates that international researchers' motivations to work in Japanese companies include professional advancement, the research environment, academic opportunities, economic factors, and cultural elements. Language proficiency in Japanese and English significantly influences career choice and mobility. The post-COVID era impacts their mobility, with funding availability, institutional support, and policy changes playing critical roles. In addition, this study highlights the need for holistic support, multilingualism, and multicultural integration among Japanese companies to enhance their competitiveness in the global talent market. Originality/Value This study fills a significant gap by offering a deeper understanding of the experiences of international researchers in Japanese companies, and by delivering insight and practical implications for policy considerations and talent management strategies in a rapidly evolving and increasingly globalized labor market.