bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is there any relationship between dietary patterns and depression and anxiety in Chinese adolescents?
Authors: Weng Ting-Ting , Hao Jia-Hu , Qian Qing-Wen , Cao Hui , Fu Ji-Ling , Sun Ying , Huang Lei , Tao Fang-Biao 
Published: November 2011

AbstractObjectiveTo determine the association between major dietary patterns characterized by factor analysis and risk of depression and anxiety symptoms among adolescents.DesignDiet and symptoms of depression and anxiety were assessed in a cross-sectional survey among students attending junior high school. Dietary patterns were derived from a self-reported FFQ, which consisted of thirty-eight items. Anthropometric measurements were also performed.SettingFour junior high schools in Bengbu city, China.SubjectsA random sample of 5003 adolescents, 11–16 years of age (mean 13·21 years).ResultsThree major dietary patterns were identified in the study based on factor analysis: ‘snack’, ‘animal food’ and ‘traditional’. The prevalence of depression symptoms, anxiety disorders and the coexistence of both were 11·2 % (560/5003), 14·6 % (732/5003) and 12·6 % (629/5003), respectively. After adjustment for potential confounders, adolescents in the highest tertile of snack dietary pattern scores had a higher odds for ‘pure’ psychological symptoms (‘depression without anxiety’, OR = 1·64; 95 % CI 1·30, 2·06; and ‘anxiety without depression’, OR = 1·87; 95 % CI 1·51, 2·31) compared with coexisting depression and anxiety (OR = 1·93; 95 % CI 1·54, 2·43). Similar to snacks, high consumption of animal foods was associated with a higher risk of psychological symptoms. Compared with low consumption, adolescents in the highest tertile of traditional dietary pattern scores had lower odds for ‘pure’ depression (OR = 0·38; 95 % CI 0·30, 0·49), ‘pure’ anxiety (OR = 0·85; 95 % CI 0·69, 1·04) and coexisting anxiety and depression (OR = 0·50; 95 % CI 0·39, 0·63).ConclusionsData from Chinese secondary-school adolescents validated findings from adult populations. Dietary patterns should be considered as important predictors of depression and anxiety among adolescents in further studies.
Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells
Authors: Novellasdemunt Laura , Obach Mercè , Millán-Ariño Lluís , Manzano Anna , Ventura Francesc , Rosa Jose Luis , Jordan Albert , Navarro-Sabate Àurea , Bartrons Ramon 
Published: November 2011

PFKFB (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) catalyses the synthesis and degradation of Fru-2,6-P2 (fructose-2,6-bisphosphate), a key modulator of glycolysis and gluconeogenesis. The PFKFB3 gene is extensively involved in cell proliferation owing to its key role in carbohydrate metabolism. In the present study we analyse its mechanism of regulation by progestins in breast cancer cells. We report that exposure of T47D cells to synthetic progestins (ORG2058 or norgestrel) leads to a rapid increase in Fru-2,6-P2 concentration. Our Western blot results are compatible with a short-term activation due to PFKFB3 isoenzyme phosphorylation and a long-term sustained action due to increased PFKFB3 protein levels. Transient transfection of T47D cells with deleted gene promoter constructs allowed us to identify a PRE (progesterone-response element) to which PR (progesterone receptor) binds and thus transactivates PFKFB3 gene transcription. PR expression in the PR-negative cell line MDA-MB-231 induces endogenous PFKFB3 expression in response to norgestrel. Direct binding of PR to the PRE box (−3490 nt) was confirmed by ChIP (chromatin immunoprecipiation) experiments. A dual mechanism affecting PFKFB3 protein and gene regulation operates in order to assure glycolysis in breast cancer cells. An immediate early response through the ERK (extracellular-signal-regulated kinase)/RSK (ribosomal S6 kinase) pathway leading to phosphorylation of PFKFB3 on Ser461 is followed by activation of mRNA transcription via cis-acting sequences on the PFKFB3 promoter.
Transport properties of CF3I thermal plasmas mixed with CO2, air or N2 as an alternative to SF6 plasmas in high-voltage circuit breakers
Authors: Cressault Y , Connord V , Hingana H , Teulet Ph , Gleizes A 
Published: November 2011

Abstract
This paper is devoted to the calculation of equilibrium compositions, thermodynamic properties (mass density, enthalpy and specific heat at constant pressure) and transport coefficients (viscosity, electrical conductivity and thermal conductivity) of air/CO2/N2–CF3I mixtures. These data are computed in the temperature range 300 K–50 kK and pressure between 1 and 32 bar. Results obtained for pure gases (CF3I, CO2, air and N2) are systematically compared with SF6. Transport coefficients for N2, CO2, CF3I and mixtures of CO2, N2 or air with CF3I are also confronted with previous published values. Particular attention is paid to the collision integral database by the use of the most accurate and recent cross-sections or interaction potentials available in the literature.
A Small-Molecule Screen Identifiesl-Kynurenine as a Competitive Inhibitor of TAA1/TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth inArabidopsis
Authors: He Wenrong , Brumos Javier , Li Hongjiang , Ji Yusi , Ke Meng , Gong Xinqi , Zeng Qinglong , Li Wenyang , Zhang Xinyan , An Fengying , Wen Xing , Li Pengpeng , Chu Jinfang , Sun Xiaohong , Yan Cunyu , Yan Nieng , Xie De-Yu , Raikhel Natasha , Yang Zhenbiao , Stepanova Anna N. , Alonso Jose M. , Guo Hongwei 
Published: November 2011

AbstractThe interactions between phytohormones are crucial for plants to adapt to complex environmental changes. One example is the ethylene-regulated local auxin biosynthesis in roots, which partly contributes to ethylene-directed root development and gravitropism. Using a chemical biology approach, we identified a small molecule, l-kynurenine (Kyn), which effectively inhibited ethylene responses in Arabidopsis thaliana root tissues. Kyn application repressed nuclear accumulation of the ETHYLENE INSENSITIVE3 (EIN3) transcription factor. Moreover, Kyn application decreased ethylene-induced auxin biosynthesis in roots, and TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS1/TRYPTOPHAN AMINOTRANSFERASE RELATEDs (TAA1/TARs), the key enzymes in the indole-3-pyruvic acid pathway of auxin biosynthesis, were identified as the molecular targets of Kyn. Further biochemical and phenotypic analyses revealed that Kyn, being an alternate substrate, competitively inhibits TAA1/TAR activity, and Kyn treatment mimicked the loss of TAA1/TAR functions. Molecular modeling and sequence alignments suggested that Kyn effectively and selectively binds to the substrate pocket of TAA1/TAR proteins but not those of other families of aminotransferases. To elucidate the destabilizing effect of Kyn on EIN3, we further found that auxin enhanced EIN3 nuclear accumulation in an EIN3 BINDING F-BOX PROTEIN1 (EBF1)/EBF2-dependent manner, suggesting the existence of a positive feedback loop between auxin biosynthesis and ethylene signaling. Thus, our study not only reveals a new level of interactions between ethylene and auxin pathways but also offers an efficient method to explore and exploit TAA1/TAR-dependent auxin biosynthesis.
Integrated DNA copy number and methylation profiling of lymphoid neoplasms using a single array
Authors: Kwee Ivo , Rinaldi Andrea , Rancoita Paola , Rossi Davide , Capello Daniela , Forconi Francesco , Giuliani Nicola , Piva Roberto , Inghirami Giorgio , Gaidano Gianluca , Zucca Emanuele , Bertoni Francesco 
Published: November 2011

SummaryChanges in DNA copy number (CN) and DNA methylation represent important aberrations for lymphomas and other cancers. Here, for the first time, we show that the Illumina Infinium Methylation (IIM) assay, although not originally designed for CN profiling, is able to estimate CN changes. We compared the IIM CN profiles to those obtained with a standard technique in a series of diffuse large B‐cell lymphomas: the profiles showed a high degree of consensus. The demonstration of CN profiling as an additional function of the IIM assay may impact the choice of platform for methylation profiling of haematological and solid tumours.
Effects of species richness on cadmium removal efficiencies of algal microcosms
Authors: Li Shao‐Peng , Li Jin‐Tian , Kuang Jia‐Liang , Duan Hong‐Nan , Zeng Yi , Shu Wen‐Sheng 
Published: November 2011

Summary1. An important factor limiting the wider application of constructed ecosystems for bioremediation of sites contaminated by toxic chemicals is their relatively low efficiency of contaminant removal. Although there is growing evidence that species‐rich ecosystems may out‐perform species‐poor ecosystems in removing excessive nutrients from water through niche partitioning, it remains unknown whether diverse ecosystems are more efficient in removing toxic chemicals from the environment, and if they are, by what mechanisms diverse ecosystems can lead to enhanced removals.2. In this study, we exposed aquatic algal microcosm ecosystems of varying species richness to a realistic cadmium (Cd) contamination scenario. We explore the mechanisms of Cd removal by assemblages with differing diversity and consider the potential role of diversity on Cd bioremediation.3. Our results suggest that Cd removal efficiencies of the algal microcosms increased with species richness. Furthermore, we found that 45% of all polycultures out‐performed the monocultures of their most efficient component species in removing Cd from the growth substrates (referred as to ‘over Cd removal’). However, the average Cd removal efficiency of the most diverse (eight‐species) polycultures was not higher than that of the most efficient monoculture (i.e. the algal species most tolerant to Cd) in this study. We also showed that the observed over Cd removal could be largely ascribed to the enhanced biomass yields of the polycultures, which were mainly driven by the positive effects of Cd‐tolerant species on Cd‐sensitive species.4. Synthesis and applications. This study demonstrates that some algal polycultures containing both Cd‐tolerant and Cd‐sensitive species may show over Cd removal through facilitation provided by Cd‐tolerant species. These polycultures are likely to be assembled and applied to achieve Cd removals higher than those of their most efficient component species in monoculture. Given that species‐rich ecosystems tend to be more environmentally stable than ones with fewer species, it would be prudent to employ diverse polycultures rather than risk the loss of individual monocultures.
Staphylococccus pseudintermedius surface proteins SpsD and SpsO mediate adherence to ex vivo canine corneocytes
Authors: Bannoehr Jeanette , Brown Jeremy K. , Shaw Darren J. , Fitzgerald Ross J. , van den Broek Adri H. M. , Thoday Keith L. 
Published: November 2011

AbstractThe Gram‐positive bacterium Staphylococcus pseudintermedius is regarded as the major cause of canine bacterial pyoderma. Despite its clinical importance, there is only very limited knowledge about the pathogenesis of S. pseudintermedius infection and the specific bacterial virulence factors involved in causing disease. Using a whole‐genome approach, we have previously identified 18 predicted cell‐wall‐anchored surface proteins representing possible virulence factors in a clinical isolate of S. pseudintermedius (strain ED99). They were designated S. pseudintermedius surface proteins A–R (SpsA–SpsR). The present study tested three of the putative Sps proteins (SpsD, SpsL and SpsO) for their ability to mediate adherence of bacteria to canine corneocytes. The three proteins were expressed on the surface of the nonpathogenic surrogate host Lactococcus lactis, a Gram‐positive bacterium that does not adhere to canine corneocytes. Adherence assays were performed using corneocytes from different healthy canine donors (n = 5), and bacterial cells were quantified using computerized image analysis. Two of the proteins, SpsD and SpsO, mediated adherence of L. lactis to canine corneocytes, suggesting that they contribute to S. pseudintermedius pathogenesis and may represent novel therapeutic targets to combat infection.
Development of near‐infrared spectroscopy calibrations to quantify starch and soluble sugar content in the roots of Rumex obtusifolius
Authors: DECRUYENAERE V , CLÉMENT C , AGNEESSENS R , LOSSEAU C , STILMANT D 
Published: November 2011

Decruyenaere V, Clément C, Agneessens R, Losseau C & Stilmant D (2011) Development of near‐infrared spectroscopy calibrations to quantify starch and soluble sugar content in the roots of Rumex obtusifolius. Weed Research 52, 1–5.SummaryThe long‐term objective of non‐chemical measures applied to control a perennial weed is to limit its vigour and regrowth capacity by reducing its acquisition of resources and subsequent allocation to reserve organs. In this context, we tested the possibility of developing near‐infrared spectroscopy (NIRS) calibrations to quantify non‐structural carbohydrates in Rumex obtusifolius roots. The database used to develop the initial calibration contained 25 reference samples in which starch and total soluble sugar content ranged from 10.4 to 47.9% and from 12.4 to 22.2% of the dry matter (DM) respectively. The calibration performances were good, with an R² higher than 0.85 for both the tested parameters and the standard error of cross‐validation (SECV) of 1.32% and 1.03% for the starch and total soluble sugar estimates. However, validation with an independent data set of samples collected later led to a high standard error of prediction (SEP) and poor performances for total soluble sugar quantification, because the range of the validation samples was not represented in the calibration data set. A global calibration covering the diversity of the initial calibration and validation data sets was developed, and validation was performed on 10 samples discarded from this global data set. With ratios of standard deviation of validation set to SEP (RPD) of 8.0 and 5.4 for total soluble sugar and starch, respectively, we concluded that both calibrations could be used to analyse R. obtusifolius roots. The necessity for the calibration to cover sample variation reinforces the need to conduct reference analyses on 5–10% of the samples of each new set analysed, to improve calibration performances.
Effect of environmental factors on seed germination and seedling emergence of invasive Ceratocarpus arenarius
Authors: EBRAHIMI E , ESLAMI S V 
Published: November 2011

Ebrahimi E & Eslami SV (2011). Effect of environmental factors on seed germination and seedling emergence of invasive Ceratocarpus arenarius. Weed Research 52, 50–59.SummaryCeratocarpus arenarius is a problematic and noxious weed of dryland farming in North Khorasan, Iran. Experiments were conducted to investigate the mechanism of seed dormancy, as well as the effect of environmental factors on germination and emergence of this species. Results showed that the pericarp is the major obstacle to seed germination; seeds without an intact pericarp had germination rates exceeding 90%. Ceratocarpus arenarius had identical germination rates in either light/dark and continuous dark conditions, indicating that this weed species is non‐photoblastic. Germination was >35% over a range of alternating light/dark temperatures (10/5, 20/10, 25/15, 30/20 and 35/25°C), with maximum germination (96%) at 25/15°C. Ceratocarpus arenarius seeds germinated at rates >20% in high levels of salinity (800 mm) and osmotic potential (−1 MPa), indicating that this species is tolerant to saline conditions and drought stress during germination and early seedling growth. Maximum germination of C. arenarius seeds occurred at a pH range of 7–9. Seedlings emerged from burial depths ranging from 0 (without covering with filter paper) to 6 cm, and the maximum emergence (94%) was observed in seeds placed on the soil surface covered with three layers of filter paper. This suggests that minimum‐ and no‐till systems would increase seedling emergence of this species through maintaining crop residues and seeds on the soil surface. These attributes, coupled with tolerance to salinity and drought stress during germination, should be taken into account when managing C. arenarius.
A randomized placebo‐controlled trial of rush preseasonal depigmented polymerized grass pollen immunotherapy*
Authors: Pfaar O. , Urry Z. , Robinson D. S. , Sager A. , Richards D. , Hawrylowicz C. M. , Bräutigam M. , Klimek L. 
Published: November 2011

To cite this article: Pfaar O, Urry Z, Robinson DS, Sager A, Richards D, Hawrylowicz CM, Bräutigam M, Klimek L. A randomized placebo‐controlled trial of rush preseasonal depigmented polymerized grass pollen immunotherapy. Allergy 2012; 67: 272–279.Abstract:
Background:  Specific subcutaneous immunotherapy (SCIT) for seasonal rhinoconjunctivitis with unmodified allergen extracts is effective, but limited by risk of side‐effects and involves treatment over 3 years. We examined a depigmented polymerized grass pollen extract for immunogenicity and for clinical efficacy in a rush preseasonal regimen.
Methods:  Depigmented polymerized grass pollen extract was tested for proliferation and cytokine production by peripheral blood mononuclear cells. A prospective, double‐blind, placebo‐controlled trial of 195 grass pollen allergic patients treated with preseasonal rush immunotherapy using depigmented polymerized allergenic extract of mixed grass pollen was performed over 2 years. Primary outcome was combined symptom and medication score (SMS) during the peak of the second grass pollen season. Secondary outcomes included combined score over the whole season, during the first grass pollen season, individual symptom and medication scores, quality of life, well days/hell days and responder analysis. Adverse events were classified using the EAACI scale. Grass pollen‐specific IgE and IgG4 were measured before and during treatment.
Results:  Depigmented polymerized extract stimulated dose‐dependent T‐cell proliferation and cytokine production. Patients treated with preseasonal SCIT showed improved combined scores during peak season at year 2 (median 3.93, interquartile range 0.77–6.27 vs median 5.86 for placebo, 3.11–8.36, P < 0.01). Most secondary outcomes were significantly better for active treatment. Side‐effects were minimal, with no grade 3 or 4 reactions.
Conclusions:  Depigmented polymerized grass pollen extract is immunogenic and clinically effective in rush preseasonal SCIT. This form of immunotherapy may be an attractive option for some patients.
Cloning of aZoysia ZjLsLand its overexpression to induce axillary meristem initiation and tiller formation inArabidopsisand bentgrass
Authors: Yang D.‐H. , Sun H.‐J. , Goh C.‐H. , Song P.‐S. , Bae T.‐W. , Song I.‐J. , Lim Y.‐P. , Lim P.‐O. , Lee H.‐Y. 
Published: November 2011

AbstractZoysia grass and creeping bentgrass are important turf grasses used in parks, gardens and playing fields. Development of grasses with increased tiller formation will enhance their commercial cultivation. To investigate the regulatory mechanism of tiller formation, we cloned theZoysia japonica Lateral suppressor‐like (ZjLsL) gene. TheLateral suppressor(Ls) gene encodes a transcriptional regulator belonging to the plant‐specific GRAS protein family of putative transcription factors, and regulates axillary meristem initiation. A full‐length DNA of theZjLsLgene was isolated by 5′/3′ DNA walking. Phylogenetic analysis showed thatZjLsLis closely related toLsgenes. Southern blot analysis revealed that zoysia grass has two copies of theZjLsLgene.ZjLsLexpression was detected in all organs of zoysia grass but was most highly expressed in culms. Overexpression ofZjLsLin creeping bentgrass andArabidopsisplants promoted axillary bud formation. These results suggest thatZjLsLplays an important role in axillary meristem initiation and tiller formation.
Temperature controls seed germination and dormancy in the European woodland herbaceous perennial Erythronium dens‐canis (Liliaceae)
Authors: Mondoni A. , Rossi G. , Probert R. 
Published: November 2011

AbstractWe examined the germination ecology and the temperature requirements for germination of Erythronium dens‐canis, under both outdoor and laboratory conditions. E. dens‐canis is a spring flowering woodland geophyte widely distributed across Europe. Germination phenology, including embryo development and radicle and cotyledon emergence, were investigated in a natural population growing in Northern Italy. Immediately after harvest, seeds of E. dens‐canis were either sown on agar in the laboratory under simulated seasonal temperatures or placed in nylon mesh sachets and buried in the wild. Embryos, undifferentiated at the time of seed dispersal, grew during summer and autumn conditions in the laboratory and in the wild, culminating in radicle emergence in winter when temperatures fell to ∼5 °C. Emergence of cotyledons did not occur immediately after radicle emergence, but was delayed until the end of winter. Laboratory experiments showed that temperature is the main factor controlling dormancy and germination, with seeds becoming non‐dormant only when given warmth, followed by cold stratification. Unlike seeds of E. dens‐canis that germinate in winter, in other Erythronium species radicle emergence occurs in autumn, while in some it is delayed until seeds are transferred from winter to spring conditions. Our results suggest that there is genetic and environmental control of the expression of seed dormancy amongst Erythronium species, which is related to local climate.
Pediatric anesthetic meetings and conferences
Authors: Brown T.C.K. 
Published: November 2011

World Paediatric Anaesthetic meetings (held in relation to World Congress of Anesthesiologists)In 1984, David Steward (in Figure 1, front row) and Seizo Iwai (Figure 2) organized a meeting of pediatric anesthetists in Manila during the World Congress of Anesthesiologists. Following the meeting, there was a dinner at which John Zorab, then Secretary of the World Federation of Societies of Anaesthesiologists (WFSA), told the audience that if they wanted to set up a Paediatric Committee in the WFSA, they should request to do so immediately. A show of hands at this informal occasion showed a majority but not unanimous approval (because no aims and objectives had been defined for the committee). It was established at the WFSA Executive meeting the next day. Eventually, a multiauthored WFSA handbook on Pediatric Anesthesia, initiated by David Steward and finalized by Anneke Meursing, was produced some years later. Speakers at World Paediatric Anaesthesia Meeting in Melbourne, following the World Congress of Anesthesiologists in Sydney, April 1996. Front: M. Rawicz (Poland), C. Riquelme (Chile), A. Meursing #(the Netherland), D. Steward* (Canada); 2nd: C. Cote (USA), P. Limoges (Canada), G, Goresky* (Canada), F. Berry (USA); 3rd: C. da Silva(Brazil), P. Kempthorne (NZ), J. Moray (USA), D. Baines (Australia), F. Veckymans (Belgium); 4th: M. Yamashita, (Japan), P. Morris (UK), D. Hatch (UK), M. Marx (Uruguay), K. Brown* (Australia); 5th: S. Rajev (Russia), J. Overton (Australia), D. Pawar (India), I. Mackenzie (Australia). *Organized World Paediatric Anaesthetic meetings. #Organized 1st and 2nd FEAPA congresses.image Seizo (Jake) Iwai from Kobe, Japan.image