bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: Effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations
Authors: Becker Mara L. , van Haandel Leon , Gaedigk Roger , Lasky Andrew , Hoeltzel Mark , Stobaugh John , Leeder J. Steven 
Published: February 2010

AbstractObjectiveIntracellular methotrexate (MTX) polyglutamates (MTXGlu) have been shown to be potentially useful biomarkers of clinical response in adult patients with rheumatoid arthritis. The present study was undertaken to measure intracellular MTXGlu concentrations in a cohort of patients with juvenile idiopathic arthritis (JIA) to determine the predictors of MTXGlu variability in these patients.MethodsBlood samples were obtained from patients with JIA who were being treated with a stable dose of MTX for ≥3 months. Clinical data were collected by chart review. Concentrations of MTXGlu1–7 in red blood cell lysates were quantitated using an innovative ion‐pairing chromatography procedure, with detection by mass spectrometry.ResultsPatients with JIA from a single center (n = 99; mean ± SD age 117.8 ± 56.5 months, 69 female) were included in the analysis. The mean ± SD dose of MTX was 0.51 ± 0.25 mg/kg per week, with a median treatment duration of 18 months (interquartile range 3–156 months). MTX was administered subcutaneously in 66 patients (67%). Fifty‐six patients (57%) had active arthritis at the time of the clinic visit. Total intracellular MTXGlu (MTXGluTOT) concentrations varied 40‐fold, with a mean ± SD total concentration of 85.8 ± 48.4 nmoles/liter. Concentrations of each MTXGlu subtype (MTXGlu1–7) were measured individually and as a percentage of MTXGluTOT in each patient. MTXGlu3 was the most prominent subtype identified, comprising 42% of MTXGluTOT, and the interindividual variability in the concentration of MTXGlu3 was the most highly correlated with that of MTXGluTOT (r = 0.96). The route of MTX administration was significantly associated with MTXGlu1–5 subtypes; higher concentrations of MTXGlu1 + 2 were observed in patients receiving oral doses of MTX, whereas higher concentrations of MTXGlu3–5 were observed in patients receiving subcutaneous doses of MTX (P < 0.0001).ConclusionIn this cohort of patients with JIA, the MTXGluTOT concentration varied 40‐fold. Individual MTXGlu metabolites (MTXGlu1–7), which have, until now, not been previously reported in patients with JIA, were detected. The route of MTX administration contributed to the variability in concentrations of MTXGlu1–5.
Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4
Authors: Coles Jeffrey M. , Zhang Ling , Blum Jason J. , Warman Matthew L. , Jay Gregory D. , Guilak Farshid , Zauscher Stefan 
Published: February 2010

AbstractObjectiveTo assess the role of the glycoprotein PRG4 in joint lubrication and chondroprotection by measuring friction, stiffness, surface topography, and subsurface histology of the hip joints of Prg4−/− and wild‐type (WT) mice.MethodsFriction and elastic modulus were measured in cartilage from the femoral heads of Prg4−/− and WT mice ages 2, 4, 10, and 16 weeks using atomic force microscopy, and the surface microstructure was imaged. Histologic sections of each femoral head were stained and graded.ResultsHistologic analysis of the joints of Prg4−/− mice showed an enlarged, fragmented surface layer of variable thickness with Safranin O–positive formations sometimes present, a roughened underlying articular cartilage surface, and a progressive loss of pericellular proteoglycans. Friction was significantly higher on cartilage of Prg4−/− mice at age 16 weeks, but statistically significant differences in friction were not detected at younger ages. The elastic modulus of the cartilage was similar between cartilage surfaces of Prg4−/− and WT mice at young ages, but cartilage of WT mice showed increasing stiffness with age, with significantly higher moduli than cartilage of Prg4−/− mice at older ages.ConclusionDeletion of the gene Prg4 results in significant structural and biomechanical changes in the articular cartilage with age, some of which are consistent with osteoarthritic degeneration. These findings suggest that PRG4 plays a significant role in preserving normal joint structure and function.
A simple and efficient device for demonstrating cross‐sectional anatomy of the head
Authors: Zamarioli Ariane , Demaman Aline Santos , Bim Waldeci Roberto , Homem Jefferson Mallman , Thomazini Jose Antonio 
Published: February 2010

AbstractDescribed in this article is a novel device that facilitates study of the cross‐sectional anatomy of the human head. In designing our device, we aimed to protect sections of the head from the destructive action of handling during anatomy laboratory while also ensuring excellent visualization of the anatomic structures. We used an electric saw to create 15‐mm sections of three cadaver heads in the three traditional anatomic planes and inserted each section into a thin, perforated display box made of transparent acrylic material. The thin display boxes with head sections are kept in anatomical order in a larger transparent acrylic storage box containing formaldehyde solution, which preserves the specimens but also permits direct observation of the structures and their anatomic relationships to each other. This box‐within‐box design allows students to easily view sections of a head in its anatomical position as well as to examine internal structures by manipulating individual display boxes without altering the integrity of the preparations. This methodology for demonstrating cross‐section anatomy allows efficient use of cadaveric material and technician time while also giving learners the best possible handling and visualization of complex anatomic structures. Our approach to teaching cross‐sectional anatomy of the head can be applied to any part of human body, and the value of our device design will only increase as more complicated understandings of cross‐sectional anatomy are required by advances and proliferation of imaging technology. Anat Sci Educ 2010. © 2010 American Association of Anatomists.
Petri nets based FPGA controller of PDP sustainer with half‐voltage energy recovery circuit
Authors: Kuo Jian‐Long , Chao Kai‐Lun , Lee Li‐Shiang 
Published: February 2010

AbstractThis paper proposes a FPGA controller design of a driver circuit based Petri nets for the Plasma Display Panel (PDP). In such a driver circuit, complicated control logic is required in the PDP sustainer circuit to implement the sustaining voltage waveform. The control logic has the zero‐switching behaviour for the driver circuit to provide better efficiency for the driving circuit. Conventionally, the VHDL programmer does not have a systematic way to program the control logic. Time delay problem of logic components in logic controller may occur under high frequency operation. With the help of the proposed Petri nets approach, the VHDL programming for the PDP driver circuit can be easier in a systematic way. Also, this paper illustrates three types of sustainers with Petri nets based FPGA controller. The basic full‐bridge and full‐voltage sustainers are used to compare the performance with the proposed half‐voltage sustainer. Details of the circuit operation are described. From the experimental results, the performance such as efficiency, luminance, and gamma curve are assessed to show the effectiveness of the proposed half‐voltage sustainer. It is believed that the proposed Petri nets based control circuit is very powerful for the practical application of the PDP sustainer circuit. Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Chattering reduction of sliding mode control by low‐pass filtering the control signal
Authors: Tseng Ming‐Lei , Chen Min‐Shin 
Published: February 2010

AbstractThe conventional approach to reducing control signal chattering in sliding mode control is to use the boundary layer design. However, when there is high‐level measurement noise, the boundary layer design becomes ineffective in chattering reduction. This paper, therefore, proposes a new design for chattering reduction by low‐pass filtering the control signal. The new design is non‐trivial since it requires estimation of the sliding variable via a disturbance estimator. The new sliding mode control has the same performance as the boundary layer design in noise‐free environments, and outperforms the boundary layer design in noisy environments. Copyright © 2010 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society
Task formats and ambiguity aversion
Authors: Liu Hsin‐Hsien 
Published: February 2010

AbstractThis paper proposes that task format (choosing or rejecting) moderates the effect of ambiguity aversion. Specifically, an ambiguous option is more attractive in a choosing task than in a rejecting task compared with a risky option. The author performed three experiments to test the propositions. In the first experiment, participants showed less ambiguity aversion when they had to choose a preferred option (risky or ambiguous) compared with when they had to reject an option they preferred less. In the second experiment with a monetary incentive, participants had to form a cash‐equivalent estimate for both a risky gamble and an ambiguous gamble in a traditional Ellsberg scenario. The ambiguous option emerged as more attractive than the risky option in the choosing task compared with the rejecting task. The third experiment showed that the participants' decision rationale mediated the effect of the task format on choice. These three experiments support the proposition that task formats moderate the effect of ambiguity aversion. On the basis of the findings, the author provides suggestions for practice and further research. Copyright © 2010 John Wiley & Sons, Ltd.
ChemInform Abstract: Evolution of the Electronic Structure and Properties of Neutral and Charged Aluminum Phosphide Clusters: A Comprehensive Analysis
Authors: Guo Ling 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Quantum Mechanical Study of TiCl3 α, β and γ Crystal Phases: Geometry, Electronic Structure and Magnetism
Authors: Sementa L. , D'Amore M. , Barone V. , Busico V. , Causa' M. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sn‐Flux Syntheses, Characterizations and Bonding Analyses of OsB and TiB2.
Authors: Fokwa Boniface P. T. , Misse Patrick R. N. , Gillessen Michael , Dronskowski Richard 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Modulated Lanthanum Chains in the Crystal Structure of La3.65[Ru(C2)3].
Authors: Davaasuren Bambar , Dashjav Enkhtsetseg , Doert Thomas , Kreiner Guido , Schnelle Walter , Wagner Frank R. , Mihalkovic Marek , Kniep Ruediger 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Phase Relationships in the Gd—Ti—Sn Ternary System at 473 K and the New Compound GdSn4Ti6.
Authors: Ma Jianbo , Zhan Yongzhong , She Jia , Yang Zhulin , Liang Jianlie 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Description of Anhydrous (Black) Dioptase as a S = 1/2 Uniform Antiferromagnetic Chain System.
Authors: Law Joseph M. , Hoch Constantin , Whangbo Myung‐Hwan , Kremer Reinhard K. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Experimental Investigation on the Phase Equilibria of the Mn—Ni—Zn System at 400 °C.
Authors: Liang Jian lie , Du Yong , Liao Chang zhong , Tang Yi yuan , Nong Liang qin , Zheng Feng , Xu Hong hui 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Ternary Linear Compound T2 and Its Phase Equilibrium Relationships in Mg—Zn—Nd System at 400 °C.
Authors: Huang M. L. , Li H. X. , Ding H. , Tang Z. Y. , Mei R. B. , Zhou H. T. , Ren R. P. , Hao S. M. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phase Equilibria in the Fe—Ti—Zr System at 1023 K.
Authors: Zhou Guojun , Zeng Dechang , Liu Zhongwu 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intercalation/Deintercalation of Oxygen: A Sequential Evolution of Phases in Ce2O3/CeO2—ZrO2 Pyrochlores.
Authors: Achary S. Nagabhusan , Sali Sanjay K. , Kulkarni Narendra K. , Krishna P. Siva Ram , Shinde Anil B. , Tyagy Avesh K. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses and Characterization of Two Alkali‐Metal Zinc Borates, α‐LiZnBO3 and Li0.48Na0.52ZnBO3.
Authors: Chen Xuean , Yang Chunyan , Chang Xinan , Zang Hegui , Xiao Weiqiang 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Processing Method of CaZn2(OH)6·2H2O Powders: Photoluminescence and Growth Mechanism.
Authors: Xavier C. S. , Sczancoski J. C. , Cavalcante L. S. , Paiva‐Santos C. O. , Varela J. A. , Longo E. , Li M. Siu 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sn94‐ Zintl Ions as Reactive Precursor for Neat Solids: Syntheses and Crystal Structures of Rb4[SnTe4], KxCs4‐x[SnTe4], and KxCs10‐x[Sn4Te12].
Authors: Wang Jian‐Qiang , Hlukhyy Viktor , Faessler Thomas F. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal Structure and Physical Properties of RbNb4Br11.
Authors: Habermehl Katja , Kleinke Holger , Meyer Gerd 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Structure, and Magnetic Property of Hexagonal Perovskite Ba5Sn1.1Mn3.9O15.
Authors: Yin Congling , Li Guobao , Jin Tounan , Tao Julian , Richardson James W. , Loong Chun‐K. , Liao Fuhui , Lin Jianhua 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: In situ Synthesis of High Density Magnetic Ferrite Spinel (MgFe2O4) Compacts Using a Mixture of Conventional Raw Materials and Waste Iron Oxide.
Authors: Ahmed Y. M. Z. , Ewais E. M. M. , Zaki Z. I. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Characterization of Delafossite‐Type CuCoO2 Prepared by Ion Exchange.
Authors: Beekman M. , Salvador J. , Shi X. , Nolas G. S. , Yang J. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Synthesis of α‐Fluoro‐α‐sulfenyl‐β‐ketoesters Using DBFOX—Ph/Ni(II) Complex.
Authors: Ishimaru Takehisa , Ogawa Shinichi , Tokunaga Etsuko , Nakamura Shuichi , Shibata Norio 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Aldol Reaction of Cyclic Ketones with Aryl Aldehydes Catalyzed by a Cyclohexanediamine Derived Salt in the Presence of Water.
Authors: Lin Jin‐Hong , Zhang Cheng‐Pan , Xiao Ji‐Chang 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhenium‐Catalyzed Addition of β‐Enamino Esters to Allenes.
Authors: Kuninobu Yoichiro , Yamashita Atsuhiro , Yamamoto Shun‐ichi , Yudha S. Salprima , Takai Kazuhiko 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: endo‐Selective Diels—Alder Reaction of Methacrylonitrile: Application to the Synthesis of Georgywood.
Authors: Borosy Andras , Frater Georg , Mueller Urs , Schroeder Fridtjof 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of 1‐Hetaryl‐4‐phenylthiosemicarbazides with N,N′‐Dicyclohexylcarbodiimide.
Authors: Vas'kevich R. I. , Savitskii P. V. , Zborovskii Yu. L. , Staninets V. I. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organocatalyzed Tsuji—Trost Reaction: A New Method for the Closure of Five‐ and Six‐Membered Rings.
Authors: Vulovic Bojan , Bihelovic Filip , Matovic Radomir , Saicic Radomir N. 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Visible Light‐Driven and Chloroperoxidase‐Catalyzed Oxygenation Reactions.
Authors: Perez Daniel I. , Grau Maria Mifsud , Arends Isabel W. C. E. , Hollmann Frank 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stabilization of Pd(0) on Surface Functionalized Fe3O4 Nanoparticles: Magnetically Recoverable and Stable Recyclable Catalyst for Hydrogenation and Suzuki—Miyaura Reactions.
Authors: Amali Arlin Jose , Rana Rohit Kumar 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aminodifluorosulfinium Tetrafluoroborate Salts as Stable and Crystalline Deoxofluorinating Reagents.
Authors: Beaulieu Francis , Beauregard Louis‐Philippe , Courchesne Gabriel , Couturier Michel , LaFlamme Francois , L'Heureux Alexandre 
Published: February 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.