bluuebunny/crossref_metadata_2025_split huggingface dataset:
ЕФЕКТИВНІСТЬ АГРАРНОГО ВИРОБНИЦТВА НА МЕЛІОРОВАНИХ УГІДДЯХ ЗОНИ ПОЛІССЯ УКРАЇНИ В УМОВАХ ЗМІНИ КЛІМАТУ
Authors: Волк П. П. , Приходько Н. В. 
Published: February 2025

У статті розглянуто питання зниження ефективності аграрного виробництва на меліорованих угіддях зони Полісся України в умовах зміни клімату. Здійснено огляд ключових тенденцій та наслідків зміни клімату в Україні, які безпосередньо впливають на умови та результати ведення аграрного виробництва, в тому числі і на меліорованих угіддях зони Полісся, які мають стратегічне значення як важливий ресурс для забезпечення й підтримання продовольчої та водної безпеки країни в умовах, що складаються. Результати аналізу багаторічних даних щодо вирощування основних сільськогосподарських культур на меліорованих угіддях зони Полісся України за період 1980–2018 рр. свідчать про наявність тенденції до зниження врожайності вирощуваних культур. Для визначення подальших перспектив виконано прогнозне оцінювання впливу змін клімату на продуктивність основних сільськогосподарських культур стосовно ретроспективних результатів, яке показало загрозу можливого зниження врожайності в середньому від 15 до 60% у разі дотримання наявних підходів і практик використання меліорованих угідь зони Полісся. У зв’язку з цим, визначено перспективні заходи для розробки відповідних стратегій подальшого розвитку, у тому числі впровадження адаптивних ресурсоощадних заходів, які передбачають необхідність зміни в сортах, введення сільськогосподарських культур, стійких до загроз (передусім щодо температурного і водного режимів), а насамперед впровадження удосконалених на еколого-економічних засадах технологій і режимів водорегулювання на осушуваних землях.
Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif
Authors: Wahyuni Nur Ismi , Rindiawati Dewi , SR Nurqalbi 
Published: February 2025

Data di Indonesia kejadian partus lama menduduki urutan tertinggi di ASEAN yaitu 359 per 100.000 kelahiran hidup ibu meninggal akibat partus lama. Salah satu upaya untuk menangani kala I yaitu dengan menggunakan teknik Rebozo Dengan Teknik Birth Ball. Tujuan penelitian untuk mengetahui Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif. Desain penelitian eksperimental menggunakan rancangan posttest only control group design. Penelitian dilaksanakan di KIinik Kehamilan Sehat Pada Bulan Desember 2023, Sampel penelitian yaitu semua ibu Hamil trimester 3 dengan HPL bulan Desember di Klinik Kehamilan Sehat Dengan pembagian sampel 20 ibu kelompok Intervensi dan 20 ibu kelompok kontrol. Teknik pengambilan sampel menggunakan purposive sampling. Instrumen penelitian menggunakan SOP Teknik Rebozo dan Brithing Ball serta Patograf, dan Analisis data menggunakan Uji T-test. Hasil penelitian pada kelompok intervensi yang diberikan Teknik rebozo diperoleh nilai mean 299,55 dengan standar devisiasi 35,528, dan Pada kelompok control yang diberikan Teknik birth ball diperoleh nilai mean 404,55 dengan standar devisiasi 29,409. Hasil uji statistik menunjukan bahwa Ada Perbandingan Efektifitas Teknik Rebozo Dengan Teknik Birth Ball Terhadap Lama Persalinan Pada Ibu Melahirkan Kala 1 Fase Aktif Di Klinik Kehamilan Sehat dengan nilai p-value 0,000. Diharapkan petugas Kesehatan dapat memberikan Teknik rebozo dengan birth ball kepada ibu bersalin untuk mengurangi lama persalinan kala 1 dan sebagai bentuk meningkatkan mutu pelayanan kebidanan.
Hubungan Status Gizi dengan Kejadian Hipertensi pada Lansia di Indonesia: Systematic Literature Review
Authors: Mukarromah Siti Rizqiyatul , Nadhiroh Siti Rahayu 
Published: February 2025

Populasi lansia di Indonesia semakin meningkat, berbagai masalah kesehatan dan penyakit yang menjadi ciri khas lansia pun akan semakin meningkat. Perubahan biologis menyebabkan kecenderungan lansia menderita penyakit degeneratif kronis. Salah satu penyakit degeneratif yang sering terjadi pada lansia adalah hipertensi. Obesitas dapat memicu terjadinya hipertensi karena terganggunya aliran darah. Systematic review ini bertujuan untuk mengulas hubungan antara indeks massa tubuh dengan hipertensi pada lansia. Desain penelitian menggunakan scoping review dengan metode ceklist PRISMA-ScR. Database yang digunakan adalah Google Scholar, ScienceDirect, Willey dan Pubmed. Kriteria yang termasuk pada review ini adalah artikel original, artikel yang diterbitkan dalam Bahasa Inggris dan Bahasa Indonesia, artikel yang membahas tentang status gizi dengan kejadian hipertensi pada lansia di Negara Indonesia dan jurnal terbitan tahun 2019-2023. Seleksi review dankarakterisasi dilakukan dengan penilaian critical appraisal menggunakan Joanna Briggs Instititute (JBI). Sebanyak 1111 artikel yang berpotensi relevan, 9 artikel yang dapat digunakan Berdasarkan hasil dari 8 artikel menunjukkan bahwa terdapat hubungan antara status gizi dengan hipertensi pada lansia. Kesimpulan pada review ini adalah status gizi menjadi salah satu faktor yang menjadi penyebab terjadinya hiperteni pada lansia sehingga disarankan peneliti selanjutnya melakukan penelitian terkait pencegahan dan penanganan status gizi sehingga dapat meminimalisir terjadinya hipertensi.
Biomasa Karbon Below Ground Paraserianthes Falcataria (L.) Nielsen pada Lahan Agroforestri Tradisional di Distrik Aimas, Sorong
Authors: Ohorella Syarif , Siburian Rima H , Febriadi Ihsan 
Published: February 2025

Hutan sebagai bagian dari lingkungan memiliki peranan besar dalam menjaga kestabilan ekosistem. Salah satunya yaitu sebagai penyimpan karbon. Vegetasi berkayu di hutan bisa menjadi pencegah proses lepasnya karbon ke atmosfer melalui proses fotosintesis dimana vegetasi menyerap CO2 kemudian memecahnya dan menyimpannya dalam bentuk biomassa. Hal inilah yang menjadikan hutan penting untuk dikaji kemampuannya dalam menyimpan biomassa dan karbon khusus pada lahan Agroforestri sebagai salah satu unit managemen hutan tingkat tapak. Tujuan dilakukannya riset ini adalah untuk menyusun model persamaan alometrik guna menduga nilai biomasa karbon yang tersimpan pada bagian bawah permukaan tanah (Bellow ground) khusus tegakan pada lahan agroforestri tradisional. Metode yang digunakan adalah destruktif sampling dengan pemilihan pohon sampel secara purposive dan dipilih dua sampel pohon dengan diameter setinggi dada (dbh) yang berbeda namun berumur sama yang mewakili tegakan pada lahan agroforestri di Distrik Aimas Kabupaten Sorong. Selanjutnya di lakukan pengukuran biomassa dan karbon melalui uji laboratorium. Potensi kandungan biomassa total below ground dari 19 tegakan sengon (Paraserianthes falcataria L. Nielsen) yang di peroleh adalah sebesar 0,369 ton/ha. Kandungan karbon below ground tegakan sengon pada lahan agroforestri seluas 2,8 hektar adalah sebesar 0,184 ton C/ha
Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer
Authors: Harnoncourt Leopold , Schmoll Martin , Festin Christopher , Pflaum Laurenz , Breuss Markus , Klepetko Johanna , Dotzauer Dominik C. , Jaklin Florian J. , Maierhofer Udo , Tratnig-Frankl Philipp , Aszmann Oskar C. 
Published: February 2025

IntroductionPeripheral nerve injuries often result in incomplete recovery, particularly after the occurrence of proximal lesions, owing to the extended reinnervation time as well as consequent reductions in the regeneration supportive factors and muscle recovery potential. In these cases, supercharged end-to-side (SETS) nerve transfers preserve the continuity of the original nerves while facilitating additional axonal support to mitigate muscle atrophy. This approach enhances functional recovery and has been demonstrated to be effective in both preclinical models and clinical settings. In this study, a novel SETS nerve transfer model is presented for the upper extremity of the rat to assess the impacts on muscle function, innervation ratio, and motor neuron regeneration as well as investigate the potential to enhance motor function recovery.MethodsThe surgical interventions include transection and end-to-end repair of the musculocutaneous nerve (MCN) in Group A, transfer of the ulnar nerve (UN) to the side of the MCN in Group B, and a combination of both in Group C. The biceps muscle function was assessed 12 weeks post-surgery using electrical stimulation.ResultsMuscle assessments revealed no significant differences in force between the experimental groups. UN-related muscle reinnervation was observed only in Group C after transfer to a regenerating nerve. Retrograde labeling demonstrated motor neuron regeneration of both the MCN and UN in a distal direction toward the muscle; however, tracer uptake of the UN motor neurons following intramuscular tracer application was detected only in Group C. In contrast, stained pseudounipolar cells in the dorsal root ganglia associated with the UN and MCN revealed afferent muscle innervations in Groups B and C.DiscussionThis novel SETS nerve transfer model enables isolated electrophysiological as well as histological evaluations of all nerve sections to determine the muscle innervation ratio exactly. Our findings indicate that substantial functional efferent muscle innervation by the donor nerve is exclusively observed in a regenerating environment.
Efficacy and safety of Saccharomyces boulardii as an adjuvant therapy for the eradication of Helicobacter pylori: a meta-analysis
Authors: Li Manning , Xie Ying 
Published: February 2025

BackgroundHelicobacter pylori (H. pylori) is highly prevalent worldwide and is closely associated with many gastric conditions. Current methods for eradicating H. pylori include triple or quadruple therapy, including antibiotics, proton pump inhibitors, and bismuth agents; however, with antibiotic abuse and increased drug resistance rates, the effectiveness of traditional methods is gradually decreasing, with many adverse effects such as abdominal pain, diarrhea, and intolerance. In recent years, there has been controversy regarding whether adding Saccharomyces boulardii (S. boulardii) to traditional therapies is beneficial for eradicating H. pylori.AimTo evaluate the efficacy and safety of S. boulardii as an adjuvant therapy for the eradication of H. pylori.MethodsWe systematically searched the PubMed and Web of Science databases from January 2002 to January 2023. The primary outcome was the H. pylori eradication rate. The secondary outcomes included total adverse effects, abdominal pain, diarrhea, bloating, constipation, nausea, vomiting, taste disorders, and other adverse reactions. We evaluated the included studies for publication bias and heterogeneity. Fixed- and random-effects models were used for studies without and with heterogeneity, respectively, to calculate the risk ratios (RRs) and conduct sensitivity and subgroup analyses.ResultsNineteen studies comprising 5,036 cases of H. pylori infection were included in this meta-analysis. The addition of S. boulardii to traditional therapy significantly improved the H. pylori eradication rate [RR=1.11, 95% confidence interval (CI): 1.08–1.15] and reduced the incidence of total adverse effects (RR=0.49, 95% CI: 0.37–0.66), diarrhea (RR=0.36, 95% CI: 0.26–0.48), abdominal distension (RR=0.49, 95% CI: 0.33–0.72), constipation (RR=0.38, 95% CI: 0.26–0.57), and nausea (RR=0.50, 95% CI: 0.37–0.68). However, it did not reduce the occurrence of abdominal pain, vomiting, or taste disorders.ConclusionsS. boulardii supplementation in traditional eradication therapy significantly improves the H. pylori eradication rate and reduces the total adverse effects and incidence of diarrhea, bloating, constipation, and nausea.Systematic review registrationProspero, identifier CRD42024549780.
Reconstruction of climatic events from the 16th century in Transylvania: interdisciplinary analysis based on historical sources
Authors: Gaceu Ovidiu Răzvan , Caciora Tudor , Baias Ștefan , Morar Cezar , Dudaș Mihai , Stupariu Marius , Maxim Maria 
Published: February 2025

IntroductionUnderstanding past climate variability is essential for interpreting current and future climate trends, particularly during defining climate periods for the past two millennia, such as the Little Ice Age, which had significant socio-economic impacts.MethodsThe present study uses an interdisciplinary approach, analyzing written documents such as chronicles, diaries, and official records to extract data related to climate events in the 16th century in Transylvania (on the current territory of Romania). The obtained results were processed using statistical techniques to reconstruct the evolution of the weather during the respective period.Results and discussionThe study identifies multiple pieces of evidence associated with extreme weather events, including 40 unusually warm summers and several years of excess precipitation or drought. In particular, the period 1,527–1544 was marked by intense heat and droughts, severely affecting agriculture and causing famine. In contrast, the second half of the century is defined by increased rainfall, with numerous reports of flooding and excessive rain, particularly in the 1590s. These extreme climatic events profoundly affected society, contributing to food shortages and increased mortality from starvation and diseases (especially the plague). At the same time, compared to the territory of Western Europe, in Transylvania, heat waves and droughts were more frequent in the first half of the 16th century, while in Western Europe, these climatic phenomena were more sporadic and less intense. Finally, the manuscript emphasizes the significant role of the climate in shaping the historical and socio-economic landscape of Transylvania in the 16th century, offering perspectives on the complex interactions between the climate and the human component.
Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a prospective cohort study
Authors: Liu Zeyan , Wang Jinbo , Yang Yanfang , Cheng Jinglin , Yang Min , Zhang Ye 
Published: February 2025

BackgroundAlthough reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. However, research examining this relationship remains limited.MethodsThis single-center prospective study enrolled 308 STEMI patients. Patients were randomly assigned to training set and validation set in a 7:3 ratio. The primary outcome was MACE one-year post-STEMI. Epicardial adipose tissue mass index (EAMI) was calculated as EAT volume divided by absolute value of the EAT attenuation index, measured using coronary computed tomography angiography (CTA). The relationship between EAMI and MACE was analyzed using Kaplan–Meier curves, Cox regression, and restricted cubic spline (RCS) plots. The predictive performance of EAMI was assessed through receiver operating characteristic (ROC) curves, C-index, net reclassification index (NRI), integrated discriminant improvement (IDI), coefficient of determination (R2), calibration curves, Brier score, and decision curve analysis (DCA) with comparisons to the GRACE score. Subgroup analyses were conducted based on age, gender, body mass index (BMI), left ventricular ejection fraction (LVEF), and culprit artery.ResultsA total of 308 patients were included in the analysis, with 212 in the training set and 96 in the validation set. In the training set, Kaplan–Meier survival analysis revealed that higher EAMI levels were associated with an increased cumulative risk of MACE. Cox multivariate regression analysis indicated that EAMI was independently associated with MACE (HR = 2.349, 95% CI 1.770–3.177, P &lt; 0.001). Restricted cubic spline (RCS) analysis suggested a positive dose-response relationship between EAMI and MACE (P for nonlinearity = 0.87). EAMI showed better discriminative ability, prediction effect, accuracy, and clinical applicability compared to the traditional GRACE score. In the validation set, EAMI also demonstrated good predictive performance for MACE. Subgroup analyses suggested that EAMI's predictive ability was consistent across various demographic and clinical characteristics.ConclusionEAMI has high value in predicting MACE in patients 1-year after STEMI, helps identify high-risk patients with poor prognosis in early clinical practice.
The use of serious games for psychological education and training: a systematic review
Authors: Facchino Antonio Pio , Marchetti Daniela , Colasanti Marco , Fontanesi Lilybeth , Verrocchio Maria Cristina 
Published: February 2025

IntroductionThe present systematic review aims to synthesize and critically analyze the use of serious games in the professional training and education of psychologists and psychology students.MethodsFollowing PRISMA guidelines, database searches from inception to July 2023 (PsycINFO, PubMed, Web of Science, and Scopus) yielded 4,409 records, of which 14 met the eligibility criteria, including 17 studies. Quality assessment was performed using the Newcastle-Ottawa Scale and the Risk of Bias Tool for Randomized Trials.ResultsThe review identified three pivotal areas where serious games demonstrated significant educational impact: enhancing psychological traits and attitudes (e.g., prejudice, empathy), promoting theoretical knowledge acquisition (e.g., biopsychology), and developing professional skills (e.g., investigative interview with children). Serious games, particularly those providing feedback and modeling, significantly enhance the quality of learning and training for psychology students and professionals.DiscussionKey findings revealed that serious games operate by offering realistic, engaging, and flexible learning environments while mitigating risks associated with real-world practice. Methodological limitations, including moderate to high risk of bias in many studies, especially those that relied on cross-sectional data, underscore the need for rigorous designs and long-term evaluations. Practical implications suggest integrating serious games into curricula to address gaps in experiential learning for psychologists, facilitating skill development and knowledge retention. Future research should explore the long-term impact of serious games on professional competencies and assess their applicability across diverse educational contexts.
Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates
Authors: Wang Shuxing , Chen Zhenyi , Liang Zihao , Xu Qiang , Zhang Jiankai 
Published: February 2025

BackgroundAccording to the IDF Diabetes Atlas regularly published by International Diabetes Federation, the prevalence of diabetes and impaired glucose tolerance (IGT), diabetes-related mortality and health expenditure are becoming serious eventually at the global, regional and national level. While the data alarm people, the exact cause remains unknown. It is widely accepted that glucose metabolism can be impaired by circadian rhythms disruption and sleep disturbances, both closely linked to exposure to light at night. However, there is little direct experiment on primates to study the precise extent of how serious bright sleeping environment at night impairs glucose metabolism, what the relationship is between nocturnal brightness and the development of diabetes and IGT, any difference between male and female, and whether aging and weight are involved. This study aims to address these questions in monkeys.MethodsIn a reduced daytime bright condition resembling human living rooms, 197 Cynomolgus (130 male, 67 female) were exposed to three distinct light intensities (13, 35, 75Lux) at night for consecutive ten months. Animals were retrospectively divided into four groups according to glucose metabolic status by the end of the experimental session, spontaneous diabetes mellitus (SDM, N=11), light-induced diabetes (LID, N=83), impaired fasting glucose tolerance (IFG, N=36), and normal glucose tolerance (NGT, N=67). Data pertaining to the glucose metabolism such as concentrations of fasting glucose, glycosylated hemoglobin, plasma insulin and C-peptide were collected monthly and analyzed.Results1) Bright night exasperated glucose metabolism in individuals with pre-existing diabetes, led to premature death; 2) Stronger white light intensity-dependently induced diabetes and IFG in previous healthy monkeys: the brighter the light, the quicker the metabolism disturbance and IFG developed, and also the higher morbidity of LID and IFG; 3) Exposure to nocturnal light had a synergistic impairing effect on glucose metabolism with aging and weight. 4) Female were more susceptible to night brightness.ConclusionsLight in sleeping environment exacerbates glucose metabolism in individuals with pre-existing diabetes, leads to IFG and diabetes in healthy primates. Moreover, the harmful effects of bright night on glucose metabolism are synergistic with aging and weight.
Impact of climate change over distribution and potential range of chestnut in the Iberian Peninsula
Authors: Álvarez-Álvarez Pedro , Aviñoa-Arias Adrián , Díaz-Varela Emilio , López-Bao José Vicente , Pérez-Girón José Carlos 
Published: February 2025

IntroductionThe European chestnut (Castanea sativa Mill.) is a historically and ecologically important tree in the Iberian Peninsula. The species now faces challenges related to the abandonment of traditional management practices, and climate change, although the potential impact of the later on chestnut potential range remains unexplored.MethodsWe assessed variations in chestnut potential range under different climate change scenarios in the Iberian Peninsula, by studying the current and projected habitat suitability of the species across distinct biogeographical regions (Atlantic and Mediterranean) and Regions of Provenance (RoPs). Environmental static (topography and soil parameters) and dynamic (bioclimatic variables) factors were used to build Species Distribution Models (SDMs). Future habitat suitability projections were based on an ensemble of five global circulation models (GCMs) for two climate change scenarios included in CMIP6. The SDMs were constructed using the Random Forest algorithm.Results and DiscussionOur model achieved an accuracy of 86.82%, with high sensitivity (89.91%) and specificity (83.73%). Favourable chestnut habitats were linked to wetter regions, and included factors associated with annual and seasonal precipitations, coldest quarter temperature, soil pH and annual mean temperature. Optimal conditions for chestnut trees include precipitation exceeding 800 mm/year and mean temperature ranging from 10-15°C. Future projections suggest a potential habitat loss for chestnut and slight changes in net primary productivity. The Regions of Provenance exhibit varying levels of resilience, with the Mediterranean regions being particularly vulnerable. We highlight the need to develop mitigation strategies to facilitate chestnut resilience in the face of threats related to climate change.