bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthetic Studies on Vitamin D Analogues. Part 39. Synthesis of 1‐Deoxyeldecalcitol, a Biologically Interesting Analogue of 1α,25‐Dihydroxy‐2β‐(3‐hydroxypropoxy)vitamin D3 (Eldecalcitol).
Authors: Sasaki Hirotaka , Eto Kohei , Takahashi Keisuke , Ishihara Jun , Hatakeyama Susumi , Kubodera Noboru 
Published: September 2011

AbstractThe synthesis of 1‐deoxyeldecalcitol (IV) is realized employing Trost′s methodology involving a palladium‐catalyzed coupling between enyne (II) and bromoalkene (III) as key step.
ChemInform Abstract: V—Ni—Ti Multi‐Phase Alloy Membranes for Hydrogen Purification.
Authors: Song G. , Dolan M. D. , Kellam M. E. , Liang D. , Zambelli S. 
Published: September 2011

AbstractV85‐xTixNi15 (0 ≤ x ≤ 30) alloys are prepared by arc melting of the elements and electrical‐discharge wire cutting.
ChemInform Abstract: Structure and Magnetic Properties of Hcp and Fcc Nanocrystalline Thin Ni Films and Nanoparticles Produced by Radio Frequency Magnetron Sputtering
Authors: Kapaklis Vassilios , Pappas Spiridon D. , Poulopoulos Panagiotis , Trachylis Dimitrios , Schweiss Peter , Politis Constantin 
Published: September 2011

AbstractReview: 19 refs.
Determination and Analysis of the Thermodynamic Regimes of Xenon Plasmas
Authors: Rodriguez R. , Gil J.M. , Florido R. , Rubiano J.G. , Mendoza M.A. , Martel P. , Minguez E. 
Published: September 2011

AbstractXenon is a common element employed, for example, as impurity in magnetically confined plasmas or the medium in which radiative shocks propagate in laboratory astrophysics. In both situations, it is required the knowledge of plasma parameters such as the average ionization, the charge state distribution, the atomic level populations and the radiative properties. In most cases, the plasmas are under non‐local thermodynamic equilibrium (NLTE) conditions and these quantities should be determined by means of the so‐called collisionalradiative models. For a high Z element like xenon this is a complex task and entails a high computational cost since it is necessary to solve a very large set of rate equations. In this work are characterized the thermodynamic regimes of xenon plasmas as a function of the matter density and temperature. This fact will allow us to establish in which regions of density and temperature the assumption of local thermodynamic equilibrium (LTE) is accurate and also in which regions it can be retained to estimate some plasma parameters but not others. Moreover, it is also provided information about the average ionization in a wide range of plasma conditions which covers both LTE and NLTE regimes which is valuable information in order to optimize subsequent calculations. Finally, it is also performed an analysis of the differences of NLTE and LTE simulations on several relevant plasma parameters. With this purpose, a comparison is made between the results of the calculation using detailed NLTE modeling with simulations that use the same energy level structure, but atomic populations that are forced into LTE (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Capturing within catchment variation in evapotranspiration from montane forests using LiDAR canopy profiles with measured and modelled fluxes of water
Authors: Mitchell Patrick J. , Lane Patrick N. J. , Benyon Richard G. 
Published: September 2011

SUMMARYPatterns in forest structure and function are tightly coupled to variation in energy and soil water gradients and disturbance history across the landscape. In eucalypt forests of southern Australia, changes in forest structure may account for the majority of variation in the evapotranspiration (Et) signal across a single forest type. In this study, the potential for using light detection and ranging (LiDAR)‐derived canopy height profiles to predict key components of Et; transpiration (Esap), interception loss (Ei) and forest floor evapotranspiration (Efloor) was assessed in a mixed‐species eucalypt forest in south‐eastern Australia. Step‐wise regression was used to select suitable LiDAR canopy height indices to predict stand structural attributes at all grid points within the catchment using field plot inventory data (r2 = 0.76–0.88). Similar rates of sap velocity were observed among trees at different landscape positions and during all seasons, irrespective of tree size and stature, enabling scaling of stand‐level Esap. The revised Gash interception model was successfully used to model Ei across the catchment using stand‐level variation in canopy cover (derived from LiDAR). Similarly, Efloor was quantified spatially using variation in leaf area index and a two‐bucket numeric model to interpolate field measurements. Our results show that variation in forest structure arising from changes in elevation in these south‐facing catchments is a major determinant of forest water use and shows a threefold change in annual Et across the elevation gradient. The merging of detailed forest structural data and field‐validated Et fluxes offers promise in advancing our understanding and prediction of key ecohydrologic processes in forested catchments. Copyright © 2011 John Wiley & Sons, Ltd.
Flow Injection Analysis of Ethambutol in Antituberculosis Drugs Using a Graphite‐Paraffin Electrode as Amperometric Detector
Authors: Bellei Perantoni Camila , Soares Carbogim Luís Gustavo , Silva Semaan Felipe , Camargo Matos Renato , Lowinsohn Denise 
Published: September 2011

AbstractA graphite‐paraffin composite electrode has been used for the determination of ethambutol, an antituberculosis drug, in pharmaceutical samples by anodic oxidation. Voltammetric studies were used to characterise the electrochemical behaviour of the ethambutol in different pH solutions (3.0, 8.0 and 12.0). Quantification was carried out using amperometric detection. The detector was assembled in a flow injection apparatus and operated at +1.1 V (vs. Ag/AgCl(NaCl,sat)). The conditions for the best electrode’s response were determined by studying the influence of sample volume and flow rate. The linear response for the method was extended up to a 1.5 mmol L−1 ethambutol solution with a detection limit of 0.1 mmol L−1. The repeatability for successive injections of 1.0 mmol L−1 ethambutol solution was 0.9 % (n=26), demonstrating a good performance of the developed amperometric sensor. The analytical frequency was calculated as approximately 47 determinations h−1. Two different commercial samples were successfully analysed and the results were in good agreement with those obtained by using spectrophotometry. The advantages of the proposed amperometric method over the reference method include simplicity, low consumption of reagents and increased analytical frequency.
Studies of the Electrochemical Degradation of Acetaminophen Using a Real‐Time Biomimetic Sensor
Authors: Quintino de Oliveira Mariana Calora , Tanaka Auro Atsushi , de Vasconce los Lanza Marcos Roberto , Del PilarTaboada Sotomayor Maria 
Published: September 2011

AbstractReal‐time monitoring of the electrochemical degradation of acetaminophen was performed using a biomimetic sensor coupled to a flow injection analysis (FIA) system. Degradation of the drug was carried out at constant current density (24 to 180 mA cm−2) in an electrolyte consisting of 0.1 mol L−1 K2SO4/5.0×10−4 mol L−1 FeSO4⋅7H2O. Two commercial DSA anodes (DSA‐Cl2 and DSA‐O2) were compared. The degradation process was monitored on‐line using an amperometric sensor based on the biomimetic catalyst iron(III) tetrapyridinoporphyrazine (FeTPyPz), coupled to the degradation cell. The optimized FIA detection system employed the electrolyte solution as carrier, a flow rate of 1.25 mL min−1 and an injected sample volume of 75 µL. The real‐time data obtained showed, as expected, that acetaminophen degradation followed pseudo‐first order kinetics, with the DSA‐Cl2 anode showing a higher efficiency according to the calculated apparent rate constant values. The advantage of the proposed on‐line system is that a larger number of points can be monitored in a shorter time compared to other off‐line methods, which improves the accuracy of estimates of electrochemical degradation constants.
Decentralized static output‐feedback H∞ controller design for buildings under seismic excitation
Authors: Rubió‐Massegú J. , Palacios‐Quiñonero F. , Rossell J. M. 
Published: September 2011

SUMMARYIn this work, we present a new method in designing static output‐feedback H∞ controllers suitable for vibrational control of buildings under seismic excitation. The method produces a Linear Matrix Inequality (LMI) formulation that allows obtaining static output‐feedback controllers with different information structure constraints by imposing a convenient zero–nonzero structure on the LMI variables. The application of the proposed methodology is illustrated by designing centralized and decentralized velocity‐feedback H∞ controllers to mitigate the seismic response of a five‐story building. Copyright © 2011 John Wiley & Sons, Ltd.
A passive location system for single frequency networks using digital terrestrial TV signals
Authors: Yan Jun , Wu Lenan 
Published: September 2011

ABSTRACTIn this work, a passive location system for single frequency networks using digital terrestrial signals is proposed. A cross‐correlation method that requires a correlation with fixed frequency was introduced for time delay estimation. The idea is first online reconstruction and update of the transmitted copy of the nearest base station (BS), and then uses this signal copy for correlation with the received signal samples. A time delay extraction method combined with K‐mean clustering algorithm is developed. The minimum value of each cluster is extracted as the time delay of each BS. The BS identification can be modelled as a data association problem. A new gate that requires little statistical knowledge was utilised to solve time‐of‐arrival measurement uncertainty. Meanwhile, the data association strategy is also developed for successive data stream. Mobile station location is formulated as an optimisation problem and solved by a search processing. Simulations study was conducted to evaluate the system performance for different scenarios. The results demonstrate its robustness and high performance. Copyright © 2011 John Wiley & Sons, Ltd.
Geoarchaeological evidence of a Chola‐period tsunami from an ancient port at Kaveripattinam on the southeastern coast of India
Authors: Rajendran C.P. , Rajendran Kusala , Srinivasalu S. , Andrade Vanessa , Aravazhi P. , Sanwal Jaishri 
Published: September 2011

AbstractLiterature of the ancient Chola Dynasty (A.D. 9th–11th centuries) of South India and recent archaeological excavations allude to a sea flood that crippled the ancient port at Kaveripattinam, a trading hub for Southeast Asia, and probably affected the entire South Indian coast, analogous to the 2004 Indian Ocean tsunami impact. We present sedimentary evidence from an archaeological site to validate the textual references to this early medieval event. A sandy layer showing bed forms representing high‐energy conditions, possibly generated by a seaborne wave, was identified at the Kaveripattinam coast of Tamil Nadu, South India. Its sedimentary characteristics include hummocky cross‐stratification, convolute lamination with heavy minerals, rip‐up clasts, an erosional contact with the underlying mud bed, and a landward thinning geometry. Admixed with 1000‐year‐old Chola period artifacts, it provided an optically stimulated luminescence age of 1091 ± 66 yr and a thermoluminescence age of 993 ± 73 yr for the embedded pottery sherds. The dates of these proxies converge around 1000 yr B.P., correlative of an ancient tsunami reported from elsewhere along the Indian Ocean coasts. © 2011 Wiley Periodicals, Inc.
Preliminary study on the preservation of giant clam (Tridacnidae) shells from the Balobok Rockshelter archaeological site, south Philippines
Authors: Faylona Marie Grace Pamela G. , Lazareth Claire E. , Sémah Anne‐Marie , Caquineau Sandrine , Boucher Hugues , Ronquillo Wilfredo P. 
Published: September 2011

AbstractTridacnidae shells, a valuable archive of past environments, are common in the Balobok Rockshelter archaeological site on Sanga‐Sanga Island in the south Philippines. This site was occupied during the mid‐Holocene (ca. 5000–8800 14C yr B.P.), a period of Neolithic cultural expansion in the Philippines. This paper focuses on the preservation of two shell specimens, Hippopus hippopus and Tridacna maxima, unearthed from two mid‐Holocene layers within the rockshelter. The shells' mineralogy and microstructure (prismatic and crossed‐lamellar) were studied using micro‐Fourier transform infrared spectroscopy and scanning electron microscopy to determine if the samples were suitable as paleoenvironmental records. Both shells are still aragonitic but aragonite crystals of both microstructure types are partly dissolved. This dissolution, characteristic of meteoric water alteration, precludes their utility in paleoenvironmental geochemical studies. Nevertheless, these shells are abundant in archaeological sites in the region and may be better preserved in other depositional contexts; more studies on Philippine Tridacnidae shell diagenesis are needed. © 2011 Wiley Periodicals, Inc.
Implementation of renormalized excitonic method at ab initio level
Authors: Zhang Hongjiang , Malrieu Jean‐Paul , Ma Haibo , Ma Jing 
Published: September 2011

AbstractThe renormalized excitonic method [Hajj et al., Phys Rev B 2005, 72, 224412], in which the excited state of the whole system may be described as a linear combination of local excitations, has been implemented at ab initio level. Its performance is tested on the ionization potential and the energy gap between singlet ground state and lowest triplet for linear molecular hydrogen chains and more realistic systems, such as polyenes and polysilenes, using full configuration interaction (FCI) wave functions with a minimal basis set. The influence of different block sizes and the extent of interblock interactions are investigated. It has been demonstrated that satisfactory results can be obtained if the near degeneracies between the model space and the outer space are avoided and if interactions between the next‐nearest neighbor blocks are considered. The method can be used with larger basis sets and other accurate enough ab initio evaluations (instead of FCI) of local excited states, from blocks, or from dimers or trimers of blocks. It provides a new possibility to accurately and economically describe the low‐lying delocalized excited states of large systems, even inhomogeneous ones. © 2011 Wiley Periodicals, Inc. J Comput Chem, 2011
Factor XIIIA transglutaminase expression and secretion by osteoblasts is regulated by extracellular matrix collagen and the MAP kinase signaling pathway
Authors: Piercy‐Kotb Sarah A. , Mousa Aisha , Al‐Jallad Hadil F. , Myneni Vamsee D. , Chicatun Florencia , Nazhat Showan N. , Kaartinen Mari T. 
Published: September 2011

AbstractOsteoblast differentiation is regulated by the presence of collagen type I (COL I) extracellular matrix (ECM). We have recently demonstrated that Factor XIIIA (FXIIIA) transglutaminase (TG) is required by osteoblasts for COL I secretion and extracellular deposition, and thus also for osteoblast differentiation. In this study we have further investigated the link between COL I and FXIIIA, and demonstrate that COL I matrix increases FXIIIA levels in osteoblast cultures and that FXIIIA is found as cellular (cFXIIIA) and extacellular matrix (ecmFXIIIA) forms. FXIIIA mRNA, protein expression, cellular localization and secretion were enhanced by ascorbic acid (AA) treatment and blocked by dihydroxyproline (DHP) which inhibits COL I externalization. FXIIIA mRNA was regulated by the MAP kinase pathway. Secretion of ecmFXIIIA, and its enzymatic activity in conditioned medium, were also decreased in osteoblasts treated with the lysyl oxidase inhibitor β‐aminopropionitrile, which resulted in a loosely packed COL I matrix. Osteoblasts secrete a latent, inactive dimeric ecmFXIIIA form which is activated upon binding to the matrix. Monodansyl cadaverine labeling of TG substrates in the cultures revealed that incorporation of the label occurred at sites where fibronectin co‐localized with COL I, indicating that ecmFXIIIA secretion could function to stabilize newly deposited matrix. Our results suggest that FXIIIA is an integral part of the COL I deposition machinery, and also that it is part of the ECM‐feedback loop, both of which regulate matrix deposition and osteoblast differentiation. J. Cell. Physiol. 227: 2936–2946, 2012. © 2011 Wiley Periodicals, Inc.
Gefitinib resistance in HCC mahlavu cells: Upregulation of CD133 expression, activation of IGF‐1R signaling pathway, and enhancement of IGF‐1R nuclear translocation
Authors: Bodzin Adam S. , Wei Zhengyu , Hurtt Reginald , Gu Tina , Doria Cataldo 
Published: September 2011

AbstractHepatocellular carcinoma (HCC) is the major form of primary liver cancer which accounts for more than half million deaths annually worldwide. While the incidence of HCC is still on the rise, options of treatment are limited and the overall survival rate is poor. The acquisition of cancer drug resistance remains one of the key hurdles to successful treatment. Clearly, a thorough understanding of the underlying mechanisms is needed for new strategies to design novel treatments and/or to improve the current therapies. In the present study, we examined the expression of cancer stem cell (CSC) marker CD133, the activation of insulin‐like growth factor 1 receptor (IGF‐1R) signaling, and the nuclear translocation of IGF‐1R in HCC Mahlavu cells under the treatment of gefitinib, a cancer drug that inhibits epidermal growth factor receptor (EGFR) pathway. Our results demonstrated that Mahlavu cells exhibited strong gefitinib resistance and the CD133 expression level was dramatically increased (from 3.88% to 32%) after drug treatment. In addition, the gefitinib treated cells displayed increased levels of phosphorylation in IGF‐1R and Akt, indicating the intensified activation of this cancer‐associated signaling pathway. Moreover, we revealed that IGF‐1R underwent nuclear translocation in gefitinib treated cells using confocal microscopy. The IGF‐1R nuclear translocation was enhanced under gefitinib treatment and appeared in a dose‐dependent manner. Our findings suggest that increased IGF‐1R nuclear translocation after gefitinib treatment may contribute to the drug resistance and IGF1‐R activation, which might also associate with the upregulation of CD133 expression. J. Cell. Physiol. 227: 2947–2952, 2012. © 2011 Wiley Periodicals, Inc.
Early endosomal rerouting of major histocompatibility class I conformers
Authors: Zagorac Gordana Blagojević , Mahmutefendić Hana , Tomaš Maja Ilić , Kučić Natalia , Le Bouteiller Philippe , Lučin Pero 
Published: September 2011

AbstractMajor histocompatibility class I (MHC‐I) molecules are present at the cell surface both as fully conformed trimolecular complexes composed of heavy chain (HC), beta‐2‐microglobulin (β2m) and peptide, and various open forms, devoid of peptide and/or β2m (open MHC‐I conformers). Fully conformed MHC‐I complexes and open MHC‐I conformers can be distinguished by well characterized monoclonal antibody reagents that recognize their conformational difference in the extracellular domain. In the present study, we used these tools in order to test whether conformational difference in the extracellular domain determines endocytic and endosomal route of plasma membrane (PM) proteins. We analyzed PM localization, internalization, endosomal trafficking, and recycling of human and murine MHC‐I proteins on various cell lines. We have shown that fully conformed MHC‐I and open MHC‐I conformers segregate at the PM and during endosomal trafficking resulting in the exclusion of open MHC‐I conformers from the recycling route. This segregation is associated with their partitioning into the membranes of different compositions. As a result, the open MHC‐I conformers internalized with higher rate than fully conformed counterparts. Thus, our data suggest the existence of conformation‐based protein sorting mechanism in the endosomal system. J. Cell. Physiol. 227: 2953–2964, 2012. © 2011 Wiley Periodicals, Inc.
Endothelin‐1 promotes MMP‐13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways
Authors: Wu Min Huan , Lo Jeng‐Fan , Kuo Chia‐Hua , Lin James A. , Lin Yueh‐Min , Chen Li‐Mien , Tsai Fuu‐Jen , Tsai Chang‐Hai , Huang Chih‐Yang , Tang Chih‐Hsin 
Published: September 2011

AbstractTumor malignancy is associated with several cellular properties including proliferation and ability to metastasize. Endothelin‐1 (ET‐1) the most potent vasoconstrictor plays a crucial role in migration and metastasis of human cancer cells. We found that treatment of human chondrosarcoma (JJ012 cells) with ET‐1 increased migration and expression of matrix metalloproteinase (MMP)‐13. ET‐1‐mediated cell migration and MMP‐13 expression were reduced by pretreatment with inhibitors of focal adhesion kinase (FAK), phosphatidylinositol 3‐kinase (PI3K), Akt, and mammalian target of rapamycin (mTOR), as well as the NF‐κB inhibitor and the IκB protease inhibitor. In addition, ET‐1 treatment induced phosphorylation of FAK, PI3K, AKT, and mTOR, and resulted in increased NF‐κB‐luciferase activity that was inhibited by a specific inhibitor of PI3K, Akt, mTOR, and NF‐κB cascades. Taken together, these results suggest that ET‐1 activated FAK/PI3K/AKT/mTOR, which in turn activated IKKα/β and NF‐κB, resulting in increased MMP‐13 expression and migration in human chondrosarcoma cells. J. Cell. Physiol. 227: 3016–3026, 2012. © 2011 Wiley Periodicals, Inc.
A reproducible method for damage‐free site‐specific preparation of atom probe tips from interfaces
Authors: Felfer Peter Johann , Alam Talukder , Ringer Simon Peter , Cairney Julie Marie 
Published: September 2011

AbstractAtom probe tomography (APT) is a mass spectrometry method with atomic‐scale spatial resolution that can be used for the investigation of a wide range of materials. The main limiting factor with respect to the type of problems that can be addressed is the small volume investigated and the randomness of common sample preparation methods. With existing site‐specific specimen preparation methods it is still challenging to rapidly and reproducibly produce large numbers of successful samples from specifically selected grain boundaries or interfaces for systematic studies. A new method utilizing both focused ion beam (FIB) and transmission electron microscopy (TEM) is presented that can be used to reproducibly produce damage‐free atom probe samples with features of interest at any desired orientation with an accuracy of better than 50 nm from samples that require very little prior preparation. Microsc. Res. Tech. 2011. © 2011 Wiley‐Liss, Inc.