bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic subsurface explosive vapor concentrations: Observations and implications
Authors: Kram Mark L. , Morris Peter M. , Everett Lorne G. 
Published: December 2011

AbstractConventional vapor intrusion characterization efforts can be challenging due to background indoor air constituents, preferential subsurface migration pathways, sampling access, and collection method limitations. While it has been recognized that indoor air concentrations are dynamic, until recently it was assumed by many practitioners that subsurface concentrations did not vary widely over time. Newly developed continuous monitoring platforms have been deployed to monitor subsurface concentrations of methane, carbon dioxide, oxygen, hydrogen sulfide, total volatile organic constituents, and atmospheric pressure. These systems have been integrated with telemetry, geographical information systems, and geostatistical algorithms for automatically generating two‐ and three‐dimensional contour images and time‐stamped renderings and playback loops of sensor attributes, and multivariate analyses through a cloud‐based project management platform. The objectives at several selected sites included continuous monitoring of vapor concentrations and related physical parameters to understand explosion risks over space and time and to then design a long‐term risk reduction strategy. High‐frequency data collection, processing, and automated visualization have resulted in greater understanding of natural processes, such as dynamic contaminant vapor intrusion risk conditions potentially influenced by localized barometric pumping. For instance, contemporaneous changes in methane, oxygen, and atmospheric pressure values suggest there is interplay and that vapor intrusion risk may not be constant. As a result, conventional single‐event and composite assessment technologies may not be capable of determining worst‐case risk scenarios in all cases, possibly leading to misrepresentation of receptor and explosion risks. While dynamic risk levels have been observed in several initial continuous monitoring applications, questions remain regarding whether these situations represent special cases and how best to determine when continuous monitoring should be required. Results from a selected case study are presented and implications derived. © 2011 Wiley Periodicals, Inc.
Concentrated ownership and firm performance: does family control matter?
Authors: Singal Manisha , Singal Vijay 
Published: December 2011

AbstractIn developed markets including the United States, family‐controlled firms, in particular founder‐controlled firms, have been associated with higher firm performance than their nonfamily counterparts. Such family‐controlled firms have concentrated ownership, which, according to agency theory, reduces agency costs and leads to superior firm value. Extant research, however, is not clear whether it is the family control or concentrated ownership that bestows the advantages that lead to enhanced firm performance. By examining different types of concentrated ownership, this study evaluates whether family ownership adds value beyond that provided by concentrated ownership. Based on analyses of panel data from the Indian corporate sector, we find that, in general, firms with concentrated ownership outperform firms with dispersed ownership. Surprisingly, and more importantly, however, we find there are no significant performance differences among family‐controlled firms and firms controlled by either foreign corporations or the state. This result is consistent with the notion that concentrated ownership, not family control, is a key determinant of firm performance. Copyright © 2011 Strategic Management Society.
Promoting minority success in the sciences: The minority opportunities in research programs at CSULA
Authors: Slovacek Simeon , Whittinghill Jonathan , Flenoury Laura , Wiseman David 
Published: December 2011

AbstractGiven the large continued investment by the federal government in programs that promote academic success and the pursuit of advanced degrees in the sciences among members groups traditionally underrepresented in the sciences, there is a strong need for research which provides rigorous investigations of these programs and their impact on the target population. The current study examines programs funded by the National Institutes of Health Minority Opportunities in Research (MORE) Division Office intended to address this underrepresentation at a minority serving comprehensive university. Academic outcomes, including college graduation and acceptance into graduate programs, among undergraduate program participants are compared against a propensity score matched comparison group. Results indicate that students supported by the MORE programs had higher GPAs at graduation, took less time to graduate, and were more likely to both graduate with a science degree and enter Master's and doctoral programs in the sciences. © 2011 Wiley Periodicals, Inc. J Res Sci Teach 49: 199–217, 2012
Daily Intake of Cod or Salmon for 2 Weeks Decreases the 18:1n‐9/18:0 Ratio and Serum Triacylglycerols in Healthy Subjects
Authors: Telle‐Hansen Vibeke H. , Larsen Laila N. , Høstmark Arne T. , Molin Marianne , Dahl Lisbeth , Almendingen Kari , Ulven Stine M. 
Published: December 2011

AbstractIntake of fish and omega‐3 (n‐3) fatty acids is associated with a reduced concentration of plasma triacylglycerols (TAG) but the mechanisms are not fully clarified. Stearoyl‐CoA desaturase‐1 (SCD1) activity, governing TAG synthesis, is affected by n‐3 fatty acids. Peripheral blood mononuclear cells (PBMC) display expression of genes involved in lipid metabolism. The aim of the present study was to estimate whether intake of lean and fatty fish would influence n‐3 fatty acids composition in plasma phospholipids (PL), serum TAG, 18:1n‐9/18:0 ratio in plasma PL, as well as PBMC gene expression of SCD1 and fatty acid synthase (FAS). Healthy males and females (n = 30), aged 20–40, consumed either 150 g of cod, salmon, or potato (control) daily for 15 days. During intervention docosahexaenoic acid (DHA, 22:6n‐3) increased in the cod group (P < 0.05), while TAG concentration decreased (P < 0.05). In the salmon group both eicosapentaenoic acid (EPA, 20:5n‐3) and DHA increased (P < 0.05) whereas TAG concentration and the 18:1n‐9/18:0 ratio decreased (P < 0.05). Reduction of the 18:1n‐9/18:0 ratio was associated with a corresponding lowering of TAG (P < 0.05) and an increase in EPA and DHA (P < 0.05). The mRNA levels of SCD1 and FAS in PBMC were not significantly altered after intake of cod or salmon when compared with the control group. In conclusion, both lean and fatty fish may lower TAG, possibly by reducing the 18:1n‐9/18:0 ratio related to allosteric inhibition of SCD1 activity, rather than by influencing the synthesis of enzyme protein.
The European Psychiatric Association (EPA) guidance on suicide treatment and prevention
Authors: Wasserman D. , Rihmer Z. , Rujescu D. , Sarchiapone M. , Sokolowski M. , Titelman D. , Zalsman G. , Zemishlany Z. , Carli V. 
Published: December 2011

AbstractSuicide is a major public health problem in the WHO European Region accounting for over 150,000 deaths per year.Suicidal crisis:Acute intervention should start immediately in order to keep the patient alive.Diagnosis:An underlying psychiatric disorder is present in up to 90% of people who completed suicide. Comorbidity with depression, anxiety, substance abuse and personality disorders is high. In order to achieve successful prevention of suicidality, adequate diagnostic procedures and appropriate treatment for the underlying disorder are essential.Treatment:Existing evidence supports the efficacy of pharmacological treatment and cognitive behavioural therapy (CBT) in preventing suicidal behaviour. Some other psychological treatments are promising, but the supporting evidence is currently insufficient. Studies show that antidepressant treatment decreases the risk for suicidality among depressed patients. However, the risk of suicidal behaviour in depressed patients treated with antidepressants exists during the first 10–14 days of treatment, which requires careful monitoring. Short-term supplementary medication with anxiolytics and hypnotics in the case of anxiety and insomnia is recommended. Treatment with antidepressants of children and adolescents should only be given under supervision of a specialist. Long-term treatment with lithium has been shown to be effective in preventing both suicide and attempted suicide in patients with unipolar and bipolar depression. Treatment with clozapine is effective in reducing suicidal behaviour in patients with schizophrenia. Other atypical antipsychotics are promising but more evidence is required.Treatment team:Multidisciplinary treatment teams including psychiatrist and other professionals such as psychologist, social worker, and occupational therapist are always preferable, as integration of pharmacological, psychological and social rehabilitation is recommended especially for patients with chronic suicidality.Family:The suicidal person independently of age should always be motivated to involve family in the treatment.Social support:Psychosocial treatment and support is recommended, as the majority of suicidal patients have problems with relationships, work, school and lack functioning social networks.Safety:A secure home, public and hospital environment, without access to suicidal means is a necessary strategy in suicide prevention. Each treatment option, prescription of medication and discharge of the patient from hospital should be carefully evaluated against the involved risks.Training of personnel:Training of general practitioners (GPs) is effective in the prevention of suicide. It improves treatment of depression and anxiety, quality of the provided care and attitudes towards suicide. Continuous training including discussions about ethical and legal issues is necessary for psychiatrists and other mental health professionals.
Missing the multiple dimensions of water? Neoliberal modernization in Mexico City and Buenos Aires
Authors: Romero Lankao Patricia 
Published: December 2011

Abstract
Private participation in the management of water and sanitation has been firmly promoted and concentrated in a handful of countries and their urban centers. Latin America became one of the main recipients of investment in infrastructure projects involving private participation. However, private participation has accomplished neither the scale nor the benefits anticipated by its promoters. Not only have water and sanitation received only a tiny part of the total investment. These reforms and the theories from which they draw have failed to improve water sustainability and associated social values in urban areas of Latin America. This paper combines a theoretical framework drawing on neoliberalism with evidence from Mexico City and Buenos Aires to explore and reflect on some of the reasons why private participation has neither fulfilled its promoters’ expectations nor improved the multiple dimensions of urban water system management. It finds that the main outcomes of the neoliberal water reform were economic (improvements in registered connection and billing). Yet, other dimensions of water such as overexploitation and contamination (environmental value), unequal access to water, and fragmented and weak institutional settings (political dimension) remain. The main lesson from the reform is that the multiple values of water cannot be addressed by merely passing water utilities along with their complex set of social and environmental problems over to private companies or public utilities.
A Blinded, Randomized, Palatability Study Comparing Variations of 2 Popular Field Water Disinfection Tablets
Authors: Heiner Jason D. , Simmons Emily A. , Hile David C. , Wedmore Ian S. 
Published: December 2011

Objective Halogen-based water disinfection tablets may render an unpleasant taste to treated water. Proposed safe additives such as ascorbic acid may reduce this objectionable taste. We compared the palatability of 2 field water disinfectants: iodine-based tetraglycine hydroperiodide (TGHP) and chlorine-based chlorine dioxide (CD) both with and without the concomitant use of an ascorbic acid taste neutralizer. Methods Blinded participants randomly sampled 5 different distilled water samples containing combinations of disinfectant tablets and ascorbic acid: 1) water; 2) water with TGHP; 3) water with CD; 4) water with TGHP plus ascorbic acid; and 5) water with CD plus ascorbic acid. Participants rated beverage taste via a 100 mm visual analogue scale (VAS) and ranked the samples from “most pleasant” to “least pleasant.” Results Sixty participants evaluated the samples. On the VAS, water with TGHP tasted worst and water with CD tasted second worst. Water with TGHP plus ascorbic acid, water alone, and water with CD plus ascorbic acid measured similarly as significantly best tasting. Water with TGHP was ranked by 58% as “least pleasant” tasting, while water with TGHP and ascorbic acid was ranked by 40% as “most pleasant” tasting. Conclusions Participants found halogen-based disinfected water significantly less palatable prior to the addition of ascorbic acid. Addition of ascorbic acid to treated water created a beverage of similar preference to distilled water. These results may increase compliance with the use of disinfecting tablets by increasing the palatability of drinking water made potable via addition of ascorbic acid to halogen-based chemical disinfection.
Fighting in Thin Air: Operational Wilderness Medicine in High Asia
Authors: Rodway George W. , Muza Stephen R. 
Published: December 2011

Objective The current conflict in Afghanistan is the first major military action in which the United States and other North Atlantic Treaty Organization (NATO) forces have found themselves regularly engaged in combat at high altitudes. However, high altitude warfare is not a new concept in Asia by any means. Methods This article will offer a short general historical review of high altitude warfare in Asia and then specifically address some of the operational challenges faced by troops carrying out missions at high altitude in the ongoing conflict in Afghanistan. Additionally, there will be discussion of evidence-based interventions being used to attempt to maintain optimal health of the warfighter at high altitude in this theater of operations. Conclusions Years of research into how to alleviate the problematic nature of military operations in the high altitude environment has resulted in extensive risk management recommendations from the US Army, specifically aimed at preventing altitude-related casualties.
Risk-taking Behavior in Skiing Among Helmet Wearers and Nonwearers
Authors: Ružić Lana , Tudor Anton 
Published: December 2011

Objective To examine differences in on-the-snow ski behavior between helmet wearers and nonwearers. Methods The data were collected using a survey. Several tourist agencies helped in administrating the survey to the skiers during the 2008–2009 and 2009–2010 seasons. The survey consisted of multiple-choice questions. The subjects were asked to choose answers most suitable for their skiing style and preferred skiing technique, volume of off-piste skiing, readiness to use time measuring systems on the slopes, and group-skiing preferences, such as leading the group, beside the group, away from the group, etc. The Risk Index was then calculated for each subject. Results The answers of 710 skiers (mean age 35.5, range 16–81 years) were analyzed. The predictive power for risk-taking behavior was tested for gender, age, educational level, level of skiing, years of skiing, and helmet usage. Younger age, male gender, higher skiing level, and helmet usage were used as independent predictors for the overall Risk Index (Power [1-β err prob] = 0.942). Significantly higher risk was assessed for the male helmet wearers while the results were not significant for the female helmet wearers. The male occasional helmet wearers were found to be the most prone to risky behavior. In female nonhelmet wearers, there was a significant decrease in risk-taking behavior with age but this was not true for female helmet wearers. Conclusions For males under 35 years of age, helmet use is one of the factors influencing risk-taking on the slopes. This is demonstrated for occasional helmet wearers in particular.
Non-extractable proanthocyanidins from grapes are a source of bioavailable (epi)catechin and derived metabolites in rats
Authors: Mateos-Martín María Luisa , Pérez-Jiménez Jara , Fuguet Elisabet , Torres Josep Lluís 
Published: December 2011

The non-extractable fraction of many fruit and vegetables contains putatively bioactive polyphenolic compounds that, in most cases, have not been well characterised structurally. Non-extractable proanthocyanidins (NEPA) of a polymeric nature are part of the dietary fibre fraction of food. Using liquid chromatography coupled to a mass spectrometer equipped with an electrospray ionisation chamber and a triple quadrupole mass analyser for tandem analysis (HPLC–ESI–QqQ–MS/MS) techniques, we examine the phenolic metabolites present in urine and faeces from rats 24 h after ingestion of an NEPA-rich fraction. We show that NEPA are partially depolymerised during their transit along the intestinal tract, as evidenced by the presence of (epi)catechin (EC) monomers and dimers in faeces and phase II conjugates of EC in urine. Moreover, NEPA are further metabolised by the intestinal microbiota into smaller metabolites including phenolic acids that are present in urine as both free phenolics and conjugates with glucuronate or sulphate moieties. For the first time, we report evidence that NEPA behave in vivo as a source of phenolics that are released progressively and deliver phenolic species that come into contact with the intestinal walls and are bioavailable for at least 24 h after ingestion.
Forms of time in Alaska natural gas development
Authors: Mason Arthur 
Published: December 2011

ABSTRACTEnergy companies and builders of energy transportation infrastructure find it difficult to evaluate Arctic natural gas development. Their business critical decisions require the assessment of not just technical risks but intangible issues regarding the future and past interactions of an energy system. These concerns call attention to the problem of time. In this article, I examine three types of time from which efforts to commercialise Alaska natural gas are drawn into the temporality of global energy markets: (1) volatility time, in which price spikes determine outcome; (2) government time, in which law and regulation assist in commercial enterprise, and; (3) entrepreneurial time, in which individuals of industry take initiative. These types of expectation in Alaska natural gas development correspond consequently to three methods for fixing time and space. In short, they are three development time-spaces or chronotopes. By offering these forms of time, taking place between 2000–2005, this article draws attention to concrete visualisations of constructing a pipeline to deliver natural gas from Alaska to continental United States. I argue that these efforts represent precise and well-marked steps and reflect a specific course of development, passing from self-confident ignorance, to self-reflective consultation and finally to genuine understanding.
Global temperature evolution 1979–2010
Authors: Foster Grant , Rahmstorf Stefan 
Published: December 2011

Abstract
We analyze five prominent time series of global temperature (over land and ocean) for their common time interval since 1979: three surface temperature records (from NASA/GISS, NOAA/NCDC and HadCRU) and two lower-troposphere (LT) temperature records based on satellite microwave sensors (from RSS and UAH). All five series show consistent global warming trends ranging from 0.014 to 0.018 K yr−1. When the data are adjusted to remove the estimated impact of known factors on short-term temperature variations (El Niño/southern oscillation, volcanic aerosols and solar variability), the global warming signal becomes even more evident as noise is reduced. Lower-troposphere temperature responds more strongly to El Niño/southern oscillation and to volcanic forcing than surface temperature data. The adjusted data show warming at very similar rates to the unadjusted data, with smaller probable errors, and the warming rate is steady over the whole time interval. In all adjusted series, the two hottest years are 2009 and 2010.
Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools
Authors: San Lucas F. Anthony , Wang Gao , Scheet Paul , Peng Bo 
Published: December 2011

Abstract
Motivation: Storing, annotating and analyzing variants from next-generation sequencing projects can be difficult due to the availability of a wide array of data formats, tools and annotation sources, as well as the sheer size of the data files. Useful tools, including the GATK, ANNOVAR and BEDTools can be integrated into custom pipelines for annotating and analyzing sequence variants. However, building flexible pipelines that support the tracking of variants alongside their samples, while enabling updated annotation and reanalyses, is not a simple task.
Results: We have developed variant tools, a flexible annotation and analysis toolset that greatly simplifies the storage, annotation and filtering of variants and the analysis of the underlying samples. variant tools can be used to manage and analyze genetic variants obtained from sequence alignments, and the command-line driven toolset could be used as a foundation for building more sophisticated analytical methods.
Availability and implementation: variant tools consists of two command-line driven programs vtools and vtools_report. It is freely available at http://varianttools.sourceforge.net, distributed under a GPL license.
Contact: bpeng@mdanderson.org
A generalized approach for simulating growth and development in diverse marine copepod species
Authors: Maps Frédéric , Pershing Andrew J. , Record Nicholas R. 
Published: December 2011

Abstract
Maps, F., Pershing, A. J., and Record, N. R. 2012. A generalized approach for simulating growth and development in diverse marine copepod species. – ICES Journal of Marine Science, 69: 370–379. Predicting ecological changes under climate change requires mechanistic descriptions of the impact of environmental conditions on the physiology, life history, and population dynamics of target species. A generic framework has been developed to simulate the growth and development of copepods, a critical link in pelagic ecosystems that connects environmental variability and changes in primary production with higher trophic levels. The modelled copepods, referred to as “compupods”, are described by their body mass and developmental stage. The dynamics of the compupods are determined by three core equations: universal temperature-dependence, Holling's type II ingestion, and allometric scaling. This general framework was applied to four copepod taxa: Pseudocalanus newmani, Calanus finmarchicus, C. glacialis, and C. hyperboreus, spanning a wide range of body sizes. A genetic algorithm procedure was used to estimate the unknown parameters required to produce a good fit to observed species-specific growth and development data. The performance of the model was evaluated by comparing the influence of food and temperature on ingestion, gut clearance, and egg production rates with published relationships. Simulations of the four species suggest that small changes in the trade-off between growth and development are responsible for the interspecific diversity observed.