bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of New Canine and Feline Preventive Healthcare Guidelines Designed to Improve Pet Health
Authors:   The American Animal Hospital Association–American Veterinary Medical Association Preventive Healthcare Guidelines Task Force
Published: September 2011

The American Veterinary Medical Association (AVMA) and American Animal Hospital Association (AAHA) have jointly introduced the first Canine and Feline Preventive Healthcare Guidelines. These consensus statements provide veterinarians with a new resource for improving patient care by emphasizing the value and scope of regular pet examinations. The two guidelines provide complete recommendations for comprehensive preventive healthcare programs, published as accessible, single-page documents.
The guidelines are based on the subjective-objective-assessment-plan (SOAP) methodology of case management, a proven approach traditionally used with sick or injured patients. This logical and disciplined process is equally applicable to healthy patients and is designed to consistently deliver optimal patient care. The guidelines recommend visits for health examinations on at least an annual basis, recognizing that for many pets, more frequent visits may be appropriate, depending on the individual needs of the patient. The guidelines also provide detailed diagnostic, therapeutic, prevention, and follow up plans, to be accompanied by appropriate documentation. The inclusive content and concise format of the guidelines are designed to maximize their practical value and make them easy to implement.
Synergistic Integration of Halide Perovskite and Rare‐Earth Ions toward Photonics
Authors: Sun Jiayu , Fu Hongyang , Jing Haitong , Hu Xin , Chen Daqin , Li Fushan , Liu Yang , Qin Xian , Huang Wei 
Published: February 2025

AbstractHalide perovskites (HPs), emerging as a noteworthy class of semiconductors, hold great promise for an array of optoelectronic applications, including anti‐counterfeiting, light‐emitting diodes (LEDs), solar cells (SCs), and photodetectors, primarily due to their large absorption cross section, high fluorescence efficiency, tunable emission spectrum within the visible region, and high tolerance for lattice defects, as well as their adaptability for solution‐based fabrication processes. Unlike luminescent HPs with band‐edge emission, trivalent rare‐earth (RE) ions typically emit low‐energy light through intra‐4f optical transitions, characterized by narrow emission spectra and long emission lifetimes. When fused, the cooperative interactions between HPs and REs endow the resulting binary composites not only with optoelectronic properties inherited from their parent materials but also introduce new attributes unattainable by either component alone. This review begins with the fundamental optoelectronic characteristics of HPs and REs, followed by a particular focus on the impact of REs on the electronic structures of HPs and the associated energy transfer processes. The advanced synthesis methods utilized to prepare HPs, RE‐doped compounds, and their binary composites are overviewed. Furthermore, potential applications are summarized across diverse domains, including high‐fidelity anticounterfeiting, bioimaging, LEDs, photovoltaics, photodetection, and photocatalysis, and conclude with remaining challenges and future research prospects.
Crossing the Dimensional Divide with Optoelectronic Tweezers: Multicomponent Light‐Driven Micromachines with Motion Transfer in Three Dimensions
Authors: Li Gong , Xu Bingrui , Wang Xiaopu , Yu Jiangfan , Zhang Yifan , Fu Rongxin , Yang Fan , Gu Hongcheng , Huang Yuchen , Chen Yujie , Zhang Yanfeng , Wang Zhuoran , Shen Guozhen , Wang Yeliang , Xie Huikai , Wheeler Aaron R. , Li Jiafang , Zhang Shuailong 
Published: February 2025

AbstractMicromachines capable of performing diverse mechanical tasks in complex and constrained microenvironments are of great interest. Despite important milestones in this pursuit, until now, micromachines are confined to actuation within a single 2D plane due to the challenges of transferring motion across different planes in limited space. Here, a breakthrough method is presented to overcome this limitation: multi‐component micromachines that facilitate 3D motion transfer across different planes. These light‐driven 3D micromachines, fabricated using standard photolithography combined with direct laser writing, are assembled and actuated via programmable light patterns within an optoelectronic tweezers system. Utilizing charge‐induced repulsion and dielectrophoretic levitation effects, the micromachines enable highly efficient mechanical rotation and effective inter‐component motion transfer. Through this work, fascinating patterns of similarities are unveiled for the new microscale 3D systems when compared with the macro‐scale world in which they live, paving the way for the development of micromechanical devices and microsystems with ever increasing functionality and versatility.
Triazine‐containing Covalent Organic Polymer‐derived Grid‐Like Multilocular Spheres for Aqueous Supercapacitors
Authors: Liu Bei , Zhao Lipu , Liu Yijiang , Chen Hongbiao , Li Huaming , Yang Mei , Qiu Jieshan 
Published: February 2025

AbstractTriazine‐containing covalent organic polymers (TCOPs) with unique structures and physicochemical properties are of great potential in energy storage and conversion applications, yet how to finely tune the morphology, and the accessible active sites, and to enhance capacitive activity remains a challenge. Here, the grid‐like multilocular spheres derived from TCOP with abundant redox active sites and unique structures are fabricated via a molecular twist‐induced regulation strategy, of which the number and size of cavities can be finely modulated by changing the conformers of the twisted unit and the Ostwald ripening time. The unique structure of the as‐fabricated TCOP results in unprecedented high specific capacitance (8412 F g−1 at 1 A g−1) and enables the as‐assembled supercapacitor with an ultra‐high energy density of 675 Wh kg−1 in redox‐active electrolyte (KI‐mixed H2SO4), much better than all reported aqueous supercapacitors thus far. It is found that the high electro‐activity is due to the synergistic effect of the enhanced accessibility of active sites and the enhanced interaction of the abundant active sites with the redox‐active electrolytes. This approach may pave a new way to precise synthesis of COPs with tuned structure and properties for application‐inspired cutting‐edge electrochemical energy storage and beyond.
Thermally Induced Reversible Martensitic Phase Transition and Self‐Healing in Nickel Glycinamide Crystals
Authors: Vušak Darko , Naumov Panče , Jelčić Želimir , Matković‐Čalogović Dubravka , Prugovečki Biserka 
Published: February 2025

AbstractMartensitic phase transitions and self‐healing in molecular compounds are extremely rare, and while they carry potential for rapid energy transduction, they are currently found only by serendipity. Here, we report the observation of both phenomena in a coordination compound of glycinamide (Glyam), [Ni(H2O)2(Glyam)2]I2 (1). Upon cooling to 205–213 K, the high‐temperature polymorph of this material (1RT) transforms into twinned crystals of the low‐temperature polymorph (1LT(twinned)), while upon heating, it is converted back to 1RT in the temperature range 217–223 K. When this transformation occurs in single crystals, evolution of cracks is observed upon cooling that disappear upon heating. The forward transition 1RT→1LT(twinned) is completed in a few seconds, while the reverse one, 1LT(twinned)→1RT, proceeds up to several hours, contrary to the fast transition in polycrystalline samples. We determined the concomitant presence of 1RT and 1LT(twinned) in the same single crystal. The crystal structure analysis revealed complex inter‐ and intramolecular displacements of atoms during the transition. To the best of our knowledge, this is only the second report where a thermally induced reversible martensitic phase transition and self‐healing are observed in crystals of a coordination compound, and indicates the potential generality of these extraordinary phenomena.
Advances in the Efficient Removal of the Key Radioactive Nuclide 90Sr Using Crystalline Ion‐Exchange Materials: A Review
Authors: Hao Yucheng , Hou Cheng , Chen Changlin , Zhou Hansong , Liu Yinan , Lin Yuan , Li Haijian , Hu Kunhong 
Published: February 2025

AbstractNuclear energy, a rapidly advancing clean energy source, generates significant amounts of radioactive waste, including radioactive nuclides such as cesium (Cs+), strontium (Sr2+), and uranyl (UO22+). Among these, Sr2+ is particularly concerning due to its long half‐life, high mobility in aqueous environments, and its toxic effects on both human health and ecosystems. Its radioactive decay produces beta particles, posing significant environmental and public health risks, especially in the context of nuclear waste disposal. Recently, ion exchange has emerged as one of the most effective methodologies to deal with this challenge. Consequently, ion‐exchange materials have become a hot topic in contemporary research. This review summarizes the latest advancements in the removal of critical radioactive ions, particularly Sr2+, using ion‐exchange materials. It provides a comprehensive overview of the structures and properties of various ion‐exchange materials, explaining their ion‐exchange characteristics and exploring the complex relationship between structure and performance. Key considerations discussed include identifying cations that are most amenable to exchange within interlayer channels, evaluating the impact of channel dimensions on material efficiency, and strategies to enhance the ion‐exchange capabilities of intercalation compounds. These factors are essential for achieving high selectivity and rapid adsorption kinetics in ion‐exchange processes for Sr2+.
Modelle zur Torsionstragfähigkeit für den Neubau und für Bestandsbauwerke
Authors: Görtz Stephan , Widell Patrick 
Published: February 2025

AbstractIm Rahmen eines von der Bundesanstalt für Straßenwesen beauftragten Forschungsvorhabens wurde eine Datenbank mit 1530 Torsionsversuchen erstellt und hieran Bemessungsmodelle im Kontext der DIN EN 1992 bzw. der Nachrechnungsrichtlinie systematisch ausgewertet. Zielsetzung war es, einerseits Sicherheitsdefizite zu identifizieren und darüber hinaus Traglastpotenziale im Hinblick auf die Nachrechnung von Bestandsbauwerken aufzuzeigen.
Investigating HER2‐Low in Early Breast Cancer: Prognostic Implications and Age‐Related Prognostic Stratification
Authors: Chen Endong , Chen Chen , Chen Yingying , You Jie , Chen Nan , Xu Shenlin , Wang Qingxuan , Cai Yefeng , Hu Xiaoqu , Li Quan 
Published: February 2025

ABSTRACTBackgroundRecent studies about human epidermal growth factor receptor 2 (HER2)‐low values have garnered great interest among oncologists. We aimed to investigate whether HER2‐low impacts the prognosis of early‐stage breast cancer overall and in specific subgroups, explore differences in clinicopathologic markers, and examine the role of age in HER2‐low prognostic stratification.Materials & MethodsWe conducted a retrospective analysis of 6920 HER2‐negative breast cancer patients from the First Affiliated Hospital of Wenzhou Medical University (2010–2022). The study focused on the impact of HER2‐low status (immunohistochemistry +1 or +2, in situ hybridization not amplified) on overall survival (OS), considering the age at diagnosis.ResultsGenerally, HER2‐low status correlated with less aggressive cancer indicators. No significant prognostic differences were observed between HER2‐low and HER2‐0 in the entire cohort, HR‐positive, and HR‐negative groups. However, in TNBC patients aged ≥ 65, HER2‐low correlated with significantly better OS (HR = 0.45, 95% CI 0.24–0.83, p = 0.011), a finding consistent after multivariable adjustment (HR = 0.34, 95% CI 0.14–0.80, p = 0.014). In other subgroups, prognosis did not significantly correlate with HER2 status. The combination of HER2‐low status and age plays a key role in prognostic stratification in TNBC. Patients aged ≥ 65 with HER2‐0 had considerably poorer prognoses compared to other subgroups.ConclusionThis extensive retrospective study demonstrates that HER2‐low status cannot serve as an independent prognostic factor in the entire cohort, nor in the HR‐positive and HR‐negative groups individually. However, the combined factors of HER2‐low status and age may indicate a potential contribution to the prognostic stratification of TNBC.
Treatment Patterns and Radical Cystectomy Outcomes in Patients Diagnosed With Urothelial Nonmetastatic Muscle‐Invasive Bladder Cancer in the United States
Authors: Davies‐Teye Bernard Bright , Siddiqui M. Minhaj , Zhang Xiao , Johnson Abree , Burcu Mehmet , Onukwugha Eberechukwu , Hanna Nader 
Published: February 2025

ABSTRACTPurposeTo characterize trends and patterns in treatment characteristics and perioperative outcomes of patients with urothelial muscle‐invasive bladder cancer (MIBC).Materials and MethodsWe utilized the National Cancer Database to assess trends and patterns in treatment modalities (radical cystectomy [RC] with or without neoadjuvant/adjuvant treatments, trimodal bladder‐sparing treatment [trimodal treatment], and others) among MIBC patients diagnosed between 2004 and 2017. We also assessed trends and patterns of short‐term post‐surgery outcomes, including 30‐day and 90‐day mortality, and readmissions.ResultsAmong 83,259 MIBC patients, those who received RC, trimodal treatment, and transurethral resection of bladder tumor (TURBT) plus chemotherapy were 34,715 (41.7%), 7,372 (8.9%), and 6,171 (7.4%), respectively. A substantial proportion (29,314; 35.2%) of MIBC patients received other treatments, including TURBT‐only. From 2004 through 2017, the proportion of MIBC patients who utilized guideline‐recommended treatments, whether RC (from 36.4% to 42.8%) or trimodal treatment (from 7.9% to 10.2%), increased. Among those who received RC, there was a substantial increase in neoadjuvant chemotherapy (NAC) utilization, from 7.8% to 29.4%. Conversely, utilization of RC without perioperative treatments decreased from 62.3% to 32.7%. There was a significant decrease in 30‐day (2.8%–1.8%) and 90‐day (7.1%–5.3%) mortality rates among RC recipients.ConclusionThere was a shift in treatment modalities for MIBC, with increased utilization of RC with NAC. A decrease in post‐surgery mortality rates may indicate improved outcomes, although the unmet need for NAC utilization requires further investigation.
Relationships and Collaboration: Engaging in Research With Marginalized Communities
Authors: Hipolito‐Delgado Carlos P. , Kwag Daun , Sharma Jyotsana 
Published: February 2025

ABSTRACTDrawing on decolonizing methods and relational–cultural theory, we argue for the importance of relationship building and collaboration in counselor education research. Based on our partnerships with refugees and migrants, survivors of interpersonal violence, and youth of color, we share concrete strategies for fostering relationships and collaboration in counseling research.
Ba2BP7N14 – A Quaternary Alkaline Earth Nitridoborophosphate with a Mixed 3D Network Structure
Authors: Buda Amalina T. , Pritzl Reinhard M. , Pointner Monika M. , Steinadler Jennifer , Schnick Wolfgang 
Published: February 2025

AbstractHighly condensed alkaline earth nitridophosphates have attracted increasing scientific interest, due to their high thermal and chemical stability, as well as their promising luminescence behavior upon doping with Eu2+ for pc‐LED applications. In particular, the barely explored mixed tetrahedra‐based nitridophosphates offer a wide range of structural and compositional diversity, enabling new insights into structure‐property relationships. Herein, we report on the first quaternary alkaline earth nitridoborophosphate Ba2BP7N14, synthesized at 8 GPa and 1600 °C in a multianvil press, starting from Ba(N3)2, h‐BN and P3N5. Ba2BP7N14 crystallizes in the barylite‐1O polytype and features a highly condensed mixed (B,P)–N anionic 3D network (κ≈0.57) built up of PN4 and mixed occupied (P0.75B0.25)N4 tetrahedra. The structure was characterized by a multi‐step process involving single‐crystal and powder X‐ray diffraction (SCXRD, PXRD), elemental analysis, electron microscopy (STEM, EELS), and solid‐state 31P and 11B MAS NMR spectroscopy. The plausibility of the structural model was corroborated by low‐cost crystallographic calculations. The optical band gap and the thermal behavior of an undoped sample of Ba2BP7N14, were determined from diffuse reflectance spectroscopy and temperature‐dependent powder X‐ray diffraction, respectively. Irradiation of a Eu2+‐doped sample with near‐UV light results in a blue emission peaking at λem=422 nm.
Advancing Continuous Sign Language Recognition Through Denoising Diffusion Transformer‐Based Spatial‐Temporal Enhancement
Authors: Muhammad Kamal Suhail , Chen Yidong , Li Shaozi 
Published: February 2025

ABSTRACTThe intricate spatial‐temporal dynamics and variability of sign language gestures pose significant challenges for Continuous Sign Language Recognition (CSLR) systems. Existing models often fall short in accurately capturing these complexities, leading to performance issues and frequent misalignments. To address these shortcomings, we introduce a new approach that leverages Denoising Diffusion Models (DDMs) to improve feature representation in the visual‐sequential module of CSLR systems. Originally intended for generative tasks, DDMs have shown strong potential in representation learning through a denoising process akin to Denoising Autoencoders. Our method incorporates a denoising diffusion transformer into the CSLR framework to refine spatial‐temporal features, capitalizing on the ability of diffusion models to enhance representation quality. By conditionally denoising visual feature sequences, our approach increases the discriminative capability of the system. Additionally, we introduce an additional classifier, trained with Connectionist Temporal Classification (CTC) loss, to provide complementary supervision and further boost performance. Extensive experiments demonstrate that our method significantly improves CSLR accuracy by effectively capturing the subtle details of continuous sign language gestures and overcoming the representation limitations of current models.
Feasibility of a novel self‐assembling submucosal injection peptide solution for endoscopic mucosal resection of colorectal lesions: A multicenter study
Authors: Sato Keigo , Fukuchi Takehide , Kondo Shinpei , Nakano Yuya , Hachisu Yoko , Kasuga Kengo , Matsui Ayako , Aoki Hironori , Takizawa Kohei , Kuribayashi Shiko , Takeuchi Yoji , Uraoka Toshio 
Published: February 2025

AbstractObjectivesAlthough a novel submucosal injection material consisting of a fully synthetic, self‐assembling peptide solution, PuraLift, has recently become commercially available in Japan, there are a few reports regarding the usefulness of this solution. The aim of this study was to investigate the feasibility of PuraLift for conventional endoscopic mucosal resection (EMR) in clinical practice.MethodsThis multicenter retrospective study was conducted at the endoscopy units of five institutions from January 2023 to May 2023. Consecutive patients who underwent EMR with PuraLift for 5–20‐mm colorectal lesions were included in the introduction of this solution at each institute. The primary endpoint was the “effective resection” rate, defined as pathological complete resection, with “effective injection” defined as requiring no more than one additional injection due to adequate maintenance of mucosal lifting during EMR.ResultsIn total, 110 lesions in 70 patients were treated by conventional EMR using PuraLift. En‐bloc resection was performed for 109 (99%) lesions, and complete resection was performed for 102 (93%) lesions. More than 95% of the lesions were neoplastic. Additional injections were required in only two lesions. Both were single additional injections, and the median overall injection volume was 1.5 mL. Therefore, the effective injection rate was 93% (95% confidence interval, 86%–96%). No adverse events occurred during the study period.ConclusionsAlthough direct comparison with other materials is required, PuraLift seems feasible as an injection material for EMR.
Hypercapnia Reduces Perceived Heat Pain in Healthy Subjects
Authors: Guekos A. , Hau M. , Grob S. , Sharvit G. , Schweinhardt P. 
Published: February 2025

ABSTRACTBackgroundDanger signals modulate pain perception. Both amplification and attenuation of perceived pain are observed in healthy subjects exposed to danger signals, such as transient threats of an imminent electrical shock. However, exposure to danger signals in real life typically is not transient but constant over minutes to hours. Here, this was experimentally achieved by administering hypercapnic air (7.5% CO2). The primary objective was to investigate whether perceived heat pain would be differentially modulated during this intervention compared to regular air administration. The secondary objective assessed the potential differences of such a modulation with respect to heat intensity level.MethodsThirty‐eight participants (19 women) received two air mixtures (hypercapnic and regular air) for 13 min each, during which 18 (6 × 3) noxious heat stimuli of three different intensities were applied to the calf and rated on two scales (intensity and pleasantness/unpleasantness). Psychological and physiological states were compared between conditions using the body sensations questionnaire, self‐assessment manikins, heart rate, and galvanic skin response. Statistical analyses were performed using Bayesian estimation testing.ResultsBetween‐condition differences were statistically meaningful for all heat intensity levels, always showing reduced pain perception during hypercapnia compared to normocapnia. The magnitude of the observed hypoalgesia did not depend on heat intensity levels.ConclusionsThe presence of a continuous physiological danger signal results in hypoalgesia. Future studies need to determine whether the present results only hold for hypercapnia in healthy subjects or are generalisable to interactions between pain perception and continuous physiological danger signals in clinical pain populations.Significance StatementIt was shown that hypercapnia leads to reduced perception of noxious heat stimuli. If confirmed by neural data in future studies this could help to better understand the interaction of pain perception and continuous physiological danger signals in clinical pain conditions, potentially allowing for improved treatment of affected individuals.
DML‐GNN: ASD Diagnosis Based on Dual‐Atlas Multi‐Feature Learning Graph Neural Network
Authors: Liu Shuaiqi , Sun Chaolei , Li Jinkai , Wang Shuihua , Zhao Ling 
Published: February 2025

ABSTRACTTo better automate the diagnosis of autism spectrum disorder (ASD) and improve diagnostic accuracy, a graph neural network via dual‐atlas multi‐feature learning (DML‐GNN) model for ASD diagnosis is constructed based on the local feature information of brain atlas and the global feature information from the multi‐modal data. First, DML‐GNN constructs a dual‐atlas feature extraction module to capture the initial features of each subject. Second, it combines K‐nearest‐neighbor graphs, graph pooling, graph convolution (GCN) and graph channel attention (GCA) to construct a local feature learning module. This module extracts deep features for each subject and eliminate redundant features, and further fuses multi‐atlases features efficiently. Third, DML‐GNN constructs a global feature learning module by combining the non‐imaging information of fMRI data and graph isomorphism network (GINConv), which combines the information of multi‐modal data to construct comprehensive multi‐graph features and learns node embeddings using GINConv. Finally, multi‐layer perceptron (MLP) is used to obtain the final ASD diagnosis results. Compared with recent algorithms for ASD diagnosis on the public data set‐Autism Brain Imaging Data Exchange I (ABIDE I), our method demonstrated superior performance, underscoring its potential as an effective tool.