bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phase Behavior and Mesophase Structures of 1,3,5‐Benzene‐ and 1,3,5‐Cyclohexanetricarboxamides: Towards an Understanding of the Losing Order at the Transition into the Isotropic Phase
Authors: Timme Andreas , Kress Roman , Albuquerque Rodrigo Q. , Schmidt Hans‐Werner 
Published: June 2012

AbstractOne of the simplest and most‐versatile motifs in supramolecular chemistry is based on 1,3,5‐benzenetricarboxamides. Variation of the core structure and subtle changes in the structures of the lateral substituents govern the self‐assembly and determine the phase behavior. Herein, we provide a comprehensive comparison between the phase behavior and mesophase structure of a series of 1,3,5‐benzene‐ and 1,3,5‐cyclohexanetricarboxamides that contain linear and branched alkyl substituents. Depending on the substituent, different crystalline, plastic crystalline, and liquid crystalline phases were formed. The relatively rare columnar nematic (NC) phase was only observed in cyclohexane‐based trisamides that contained linear alkyl substituents. Of fundamental interest in liquid crystalline supramolecular systems is the transition from the mesomorphic state into the isotropic state and, in particular, the question of how the order decreases. Temperature‐dependent IR spectroscopy and XRD measurements revealed that columnar H‐bonded aggregates were still present in the isotropic phase. At the clearing transition, mainly the lateral order was lost, whilst shorter columnar aggregates still remained. A thorough understanding of the phase behavior and the mesophase structure is relevant for selecting processing conditions that use supramolecular structures in devices or as fibrillar nanomaterials.
Poly(2,5‐dimercapto‐1,3,4‐thiadiazole) as a Cathode for Rechargeable Lithium Batteries with Dramatically Improved Performance
Authors: Gao Jie , Lowe Michael A. , Conte Sean , Burkhardt Stephen E. , Abruña Héctor D. 
Published: June 2012

AbstractOrganosulfur compounds with multiple thiol groups are promising for high gravimetric energy density electrochemical energy storage. We have synthesized a poly(2,5‐dimercapto‐1,3,4‐thiadiazole) (PDMcT)/poly(3,4‐ethylenedioxythiophene) (PEDOT) composite cathode for lithium‐ion batteries with a new method and investigated its electrochemical behavior by charge/discharge cycles and cyclic voltammetry (CV) in an ether‐based electrolyte. Based on a comparison of the electrochemical performance with a carbonate‐based electrolyte, we found a much higher discharge capacity, but also a very attractive cycling performance of PDMcT by using a tetra(ethylene glycol) dimethyl ether (TEGDME)‐based electrolyte. The first discharge capacity of the as‐synthesized PDMcT/PEDOT composite approached 210 mAh g−1 in the TEGDME‐based electrolyte. CV results clearly show that the redox reactions of PDMcT are highly reversible in this TEGDME‐based electrolyte. The reversible capacity remained around 120 mAh g−1 after 20 charge/discharge cycles. With improved cycling performance and very low cost, PDMcT could become a very promising cathode material when combined with a TEGDME‐based electrolyte. The poor capacity in the carbonate‐based electrolyte is a consequence of the irreversible reaction of the DMcT monomer and dimer with the solvent, emphasizing the importance of electrolyte chemistry when studying molecular‐based battery materials.
Theoretical Insights into the Mechanism of Carbon Monoxide (CO) Release from CO‐Releasing Molecules
Authors: Vummaleti Sai Vikrama Chaitanya , Branduardi Davide , Masetti Matteo , De Vivo Marco , Motterlini Roberto , Cavalli Andrea 
Published: June 2012

AbstractWe used density functional theory to investigate the capacity for carbon monoxide (CO) release of five newly synthesized manganese‐containing CO‐releasing molecules (CO‐RMs), namely CORM‐368 (1), CORM‐401 (2), CORM‐371 (3), CORM‐409 (4), and CORM‐313 (5). The results correctly discriminated good CO releasers (1 and 2) from a compound unable to release CO (5). The predicted MnCO bond dissociation energies were well correlated (R2≈0.9) with myoglobin (Mb) assay experiments, which quantified the formation of MbCO, and thus the amount of CO released by the CO‐RMs. The nature of the MnCO bond was characterized by natural bond orbital (NBO) analysis. This allowed us to identify the key donor–acceptor interactions in the CO‐RMs, and to evaluate the MnCO bond stabilization energies. According to the NBO calculations, the charge transfer is the major source of MnCO bond stabilization for this series. On the basis of the nature of the experimental buffers, we then analyzed the nucleophilic attack of putative ligands (L′=HPO42−, H2PO4−, H2O, and Cl−) at the metal vacant site through the ligand‐exchange reaction energies. The analysis revealed that different L′‐exchange reactions were spontaneous in all the CO‐RMs. Finally, the calculated second dissociation energies could explain the stoichiometry obtained with the Mb assay experiments.
Second‐Generation Supramolecular Dendrimer with a Defined Structure due to Orthogonal Binding
Authors: Eckelmann Jens , Dethlefs Christiane , Brammer Stefan , Doğan Ahmet , Uphoff Andreas , Lüning Ulrich 
Published: June 2012

AbstractA second‐generation supramolecular dendrimer has been prepared by orthogonal multiple hydrogen bonding. In the first (inner) recognition domain, the interaction of one bis‐isocyanuric acid (25) with two branching units (21) that carry complementary Hamilton receptors has been exploited. In the second (outer) generation, the two ADDA (A=hydrogen‐bond acceptor, D=donor) receptors of each branching unit (21) have bound complementary DAAD units (4). The problem of limited solubility of the building blocks has been overcome by the introduction of branched ethylhexyl residues and by the use of flexible alkylene or oligo(ethylene glycol) linking chains. The orthogonal binding of the two hydrogen‐bonding pairs was elucidated by chemical induced shift NMR titrations, which proved that the two pairs, isocyanuric acid with the Hamilton receptor and ADDA with DAAD, bind preferentially. The formation of the supramolecular self‐assembled 1:2:4 dendrimer with a molecular weight of 5065 g mol−1 was investigated by diffusion NMR spectroscopy.
Synthesis, Coordination Behavior, and Reduction Chemistry of Cymantrenyl‐1,3‐bis(2,3,4,5‐tetraphenyl)borole
Authors: Braunschweig Holger , Damme Alexander , Gamon Daniela , Kelch Hauke , Krummenacher Ivo , Kupfer Thomas , Radacki Krzysztof 
Published: June 2012

AbstractWe describe the synthesis of base‐free bisborole [Cym†(BC4Ph4)2]—Cym†=(OC)3Mn(η5‐C5H3)—and its transformation into two fully characterized Lewis acid–base adducts with pyridine bases of the type 4‐RNC5H4 (R=tBu, NMe2). The results of electrochemical, as well as NMR and UV/Vis spectroscopic studies on [Cym†(BC4Ph4)2] and the related monoborole derivative [Cym(BC4Ph4)]—Cym=(OC)3Mn(η5‐C5H4)—provided conclusive evidence for 1) the enhanced Lewis acidity of the two boron centers that result from conjugation of two borole fragments, and 2) the fact that MnB bonding interactions between the Lewis acidic borole moieties and the Mn center are considerably less pronounced for bisborole [Cym†(BC4Ph4)2]. In addition, the reduction chemistry of [Cym†(BC4Ph4)2] has been studied in detail, both electrochemically and chemically. Accordingly, chemical reduction of [Cym†(BC4Ph4)2] with magnesium anthracene afforded the corresponding tetraanion, which features a rare MgOC bonding mode in the solid state.
A Mechanistic Study of the Utilization of arachno‐Diruthenaborane [(Cp*RuCO)2B2H6] as an Active Alkyne‐Cyclotrimerization Catalyst
Authors: Geetharani K. , Tussupbayev Samat , Borowka Julia , Holthausen Max C. , Ghosh Sundargopal 
Published: June 2012

AbstractThe reaction of nido‐[1,2‐(Cp*RuH)2B3H7] (1 a, Cp*=η5‐C5Me5) with [Mo(CO)3(CH3CN)3] under mild conditions yields the new metallaborane arachno‐[(Cp*RuCO)2B2H6] (2). Compound 2 catalyzes the cyclotrimerization of a variety of internal‐ and terminal alkynes to yield mixtures of 1,3,5‐ and 1,2,4‐substituted benzenes. The reactivities of nido‐1 a and arachno‐2 with alkynes demonstrates that a change in geometry from nido to arachno drives a change in the reaction from alkyne‐insertion to catalytic cyclotrimerization, respectively. Density functional calculations have been used to evaluate the reaction pathways of the cyclotrimerization of alkynes catalyzed by compound 2. The reaction involves the formation of a ruthenacyclic intermediate and the subsequent alkyne‐insertion step is initiated by a [2+2] cycloaddition between this intermediate and an alkyne. The experimental and quantum‐chemical results also show that the stability of the metallacyclic intermediate is strongly dependent on the nature of the substituents that are present on the alkyne.
Walking Metals in d8⋅⋅⋅d8 Hetero‐bimetallic Complexes: An Original Dynamic Phenomenon
Authors: Nebra Noel , Ladeira Sonia , Maron Laurent , Martin‐Vaca Blanca , Bourissou Didier 
Published: June 2012

AbstractIn the course of our investigations on polymetallic complexes derived from 1,3‐bis(thiophosphinoyl)indene (Ind(Ph2PS)2), we observed original fluxional behavior and report herein a joint experimental/computational study of this dynamic process. Starting from the indenylidene chloropalladate species [Pd{Ind(Ph2PS)2}Cl]− (1), the new PdII⋅⋅⋅RhI hetero‐bimetallic pincer complex [PdCl{Ind(Ph2PS)2}Rh(nbd)] (2; nbd=2,5‐norbornadiene) was prepared. X‐ray crystallography and DFT calculations substantiate the presence of a d8⋅⋅⋅d8 interaction. According to multinuclear variable‐temperature NMR spectroscopic experiments, the pendant {Rh(nbd)} fragment of 2 readily shifts in solution at room temperature between the two edges of the SCS tridentate ligand. To assess the role of the pincer‐based polymetallic structure on this fluxional behavior, the related monometallic Rh complex [Rh{IndH(Ph2PS)2}(nbd)] (3) was prepared. No evidence for a metal shift was observed in that case, even at high temperature, thus indicating that inplane pincer coordination to the Pd center plays a crucial role. The previously described PdII⋅⋅⋅IrI bimetallic complex 4 exhibited fluxional behavior in solution, but with a significantly higher activation barrier than 2. This finding demonstrates the generality of this metal‐shift process and the strong influence of the involved metal centers on the associated activation barrier. DFT calculations were performed to shed light onto the mechanism of such metal‐shift processes and to identify the factors that influence the associated activation barriers. Significantly different pathways were found for bimetallic complexes 2 and 4 on one hand and the monometallic complex 3 on the other hand. The corresponding activation barriers predicted computationally are in very good agreement with the experimental observations.
Parasite‐Based Screening and Proteome Profiling Reveal Orlistat, an FDA‐Approved Drug, as a Potential Anti Trypanosoma brucei Agent[]
Authors: Yang Peng‐Yu , Wang Min , Liu Kai , Ngai Mun Hong , Sheriff Omar , Lear Martin J. , Sze Siu Kwan , He Cynthia Y. , Yao Shao Q. 
Published: June 2012

AbstractTrypanosoma brucei is a parasite that causes African sleeping sickness in humans and nagana in livestock and is transmitted by the tsetse fly. There is an urgent need for the development of new drugs against African trypanosomiasis due to the lack of vaccines and effective drugs. Orlistat (also called tetrahydrolipstatin or THL) is an FDA‐approved antiobesity drug targeting primarily the pancreatic and gastric lipases within the gastrointestinal tract. It shows potential activities against tumors, mycobacteria, and parasites. Herein, we report the synthesis and evaluation of an expanded set of orlistat‐like compounds, some of which showed highly potent trypanocidal activities in both the bloodstream form (BSF) and the procyclic form (PCF) of T. brucei. Subsequent in situ parasite‐based proteome profiling was carried out to elucidate potential cellular targets of the drug in both forms. Some newly identified targets were further validated by the labeling of recombinantly expressed enzymes in Escherichia coli lysates. Bioimaging experiments with a selected compound were carried out to study the cellular uptake of the drug in T. brucei. Results indicated that orlistat is much more efficiently taken up by the BSF than the PCF of T. brucei and has clear effects on the morphology of mitochondria, glycosomes, and the endoplasmic reticulum in both BSF and PCF cells. These results support specific effects of orlistat on these organelles and correlate well with our in situ proteome profiling. Given the economic challenges of de novo drug development for neglected diseases, we hope that our findings will stimulate further research towards the conversion of orlistat‐like compounds into new trypanocidal drugs.
Ion‐Exchange‐Assisted Synthesis of Pt‐VC Nanoparticles Loaded on Graphitized Carbon: A High‐Performance Nanocomposite Electrocatalyst for Oxygen‐Reduction Reactions
Authors: He Guoqiang , Yan Zaoxue , Cai Mei , Shen Pei Kang , Gao Min‐Rui , Yao Hong‐Bin , Yu Shu‐Hong 
Published: June 2012

AbstractCarbide‐based electrocatalysts are superior to traditional carbon‐based electrocatalysts, such as the commercial Pt/C electrocatalysts, in terms of their mass activity and stability. Herein, we report a general approach for the preparation of a nanocomposite electrocatalyst of platinum and vanadium carbide nanoparticles that are loaded onto graphitized carbon. The nanocomposite, which was prepared in a localized and controlled fashion by using an ion‐exchange process, was an effective electrocatalyst for the oxygen‐reduction reaction (ORR). Both the stability and the durability of the Pt‐VC/GC nanocomposite catalyst could be enhanced compared with the state‐of‐the‐art Pt/C. This approach can be extended to the synthesis of other metal‐carbide‐based nanocatalysts. Moreover, this straightforward synthesis of high‐performance composite nanocatalysts can be scaled up to meet the requirements for mass production.
Experimental Support for the Role of Dispersion Forces in Aromatic Interactions
Authors: Lima Carlos F. R. A. C. , Rocha Marisa A. A. , Gomes Lígia R. , Low John N. , Silva Artur M. S. , Santos Luís M. N. B. F. 
Published: June 2012

AbstractHerein a core scaffold of 1‐phenylnaphthalenes and 1,8‐diphenylnaphthalenes with different substituents on the phenyl rings was used to study substituent effects on parallel‐displaced aromatic π⋅⋅⋅π interactions. The energetics of the interaction was evaluated in gas phase based on the standard molar enthalpies of formation, at T=298.15 K, for the compounds studied; these values were derived from the combination of the results obtained by combustion calorimetry and Knudsen/Quartz crystal effusion. A homodesmotic gas‐phase reaction scheme was used to quantify and compare the intramolecular interaction enthalpies in various substituted 1,8‐diphenylnaphthalenes. The application of this methodology allowed a direct evaluation of aromatic interactions, and showed that substituent effects on the interaction enthalpy cannot be rationalized solely on classical electrostatic grounds, because no correlation with the σmeta or σpara Hammett constants was observed. Moreover, the results obtained indicate that aromatic π⋅⋅⋅π interactions are significantly enhanced by substitution, in a way that correlates with the ability of the interacting aryl rings to establish dispersive interactions. A combined experimental and computational approach for calculation of the true aromatic π⋅⋅⋅π interaction energies in these systems, free of secondary effects, was employed, and corroborates the rationale derived from the experimental results. These findings clearly emphasize the role of dispersion and dilute the importance of electrostatic forces on this type of interactions.
ChemInform Abstract: Crystal Structure of the Fe6‐xGayGe5‐y (x ≈ 0.5, y = 1.3) Ternary Compound.
Authors: Lyutyy P. Ya. , Svitlyk V. O. , Fedorchuk A. O. 
Published: June 2012

AbstractSingle crystals of the title compound are prepared by arc‐melting of the elements and characterized by SEM and single crystal XRD.
ChemInform Abstract: Intermediate‐Valent Cerium in Ce2Ru4Mg17 and a Group‐Subgroup Scheme for La9Ru4In5 and Ce9Ru4Ga5.
Authors: Linsinger Stefan , Hoffmann Rolf‐Dieter , Eul Matthias , Poettgen Rainer 
Published: June 2012

AbstractCe2Ru4Mg17 is synthesized by high‐frequency melting of the elements in a Ta ampule and characterized by powder and single crystal XRD, and magnetic measurements.
ChemInform Abstract: Low‐Temperature Diffusion of Oxygen Through Ordered Carbon Vacancies in Zr2Cx: The Formation of Ordered Zr2CxOy.
Authors: Tian Yongjun , et al. et al. 
Published: June 2012

AbstractLow‐temperature oxygen diffusion in carbon vacancy ordered ZrC0.6 and the induced formation of oxygen ordered ZrC0.6O0.4 is characterized by XRD, SAED, and TEM.
ChemInform Abstract: Photocatalytic and Photoelectric Properties of Cubic Ag3PO4 Sub‐microcrystals with Sharp Corners and Edges.
Authors: Bi Yingpu , Hu Hongyan , Ouyang Shuxin , Lu Gongxuan , Cao Junyu , Ye Jinhua 
Published: June 2012

AbstractThe title sub‐microcubes are prepared in high yields by reaction of AgNO3 dissolved in aqueous NH3 with Na2HPO4 at room temperature.
ChemInform Abstract: Synthesis and Visible Light Photocatalytic Activity of β‐AgVO3 Nanowires.
Authors: Xu Jing , Hu Chenguo , Xi Yi , Wan Buyong , Zhang Cuiling , Zhang Yan 
Published: June 2012

AbstractThe title nanowires with diameters of about 200—700 nm and lengths up to 300 μm are hydrothermally synthesized from AgNO3 powder, vanadium foil, and H2O (autoclave, 200 °C, 20 h).
ChemInform Abstract: New Layered Compounds with Honeycomb Ordering: Li3Ni2BiO6, Li3NiM′BiO6 (M′: Mg, Cu, Zn), and the Delafossite Ag3Ni2BiO6.
Authors: Berthelot Romain , Schmidt Whitney , Muir Sean , Eilertsen James , Etienne Laetitia , Sleight A. W. , Subramanian M. A. 
Published: June 2012

AbstractThe lithium nickel bismuthates of title are prepared by solid state reactions using Li2CO3, NiO, Bi2O3, and MgO, CuO, or ZnO as starting materials (Au crucible, air or O2 flow, 550—900 °C, 12—48 h).
ChemInform Abstract: Mo‐Substituted Keggin Tungstosilicate Microtubes: Preparation and Characterization.
Authors: Shen Yan , Peng Jun , Zhang Huanqiu , Yu Xia , Bond Alan M. 
Published: June 2012

AbstractK3.8Na0.2SiMoVIW11O40 ·4H2O microtubes are prepared by addition of HCl to an aqueous solution of α‐K8[SiW11O39] and Na2MoO4 (80 °C, 15 min, yield given in g).
ChemInform Abstract: A New Partially Deprotonated Mixed‐Valence Manganese(II,III) Hydroxide—Arsenate with Electronic Conductivity: Magnetic Properties of High‐ and Room‐Temperature Sarkinite.
Authors: de Pedro Imanol , Rojo Jose M. , Rius Jordi , Vallcorba Oriol , Ruiz de Larramendi Idoia , Rodriguez Fernandez Jesus , Lezama Luis , Rojo Teofilo 
Published: June 2012

AbstractThe new three‐dimensional compound Mn8(O4Hx)(AsO4)4 (x ≈ 3) is prepared by heating Mn2(OH)AsO4 in air at 500 °C.
ChemInform Abstract: β‐Technetium Trichloride: Formation, Structure, and First‐Principles Calculations.
Authors: Poineau Frederic , Johnstone Erik V. , Weck Philippe F. , Forster Paul M. , Kim Eunja , Czerwinski Kennth R. , Sattelberger P. 
Published: June 2012

AbstractThe new polymorph β‐TcCl3 is prepared by reaction of Tc metal and Cl2 gas (450 °C, 24 h, yield given in g) and characterized by single crystal XRD and DFT calculations.
ChemInform Abstract: A Polyoxometalate—Cyanometalate Multilayered Coordination Network.
Authors: Compain Jean‐Daniel , Nakabayashi Koji , Ohkoshi Shin‐ichi 
Published: June 2012

AbstractThe new compound [ε‐PMo12O37(OH)3{La (H2O)5(Fe (CN)6)0.25}4] ·12H2O (I) is synthesized from a solution of [ε‐PMo12O36(OH)4{La (H2O)4}4]Br5 and Na4[Fe(CN)6] in H2O (20 °C, 5 min, 84% yield).
ChemInform Abstract: Electrochemical Oxidation of Catechols in the Presence of Ketene N,O‐Acetals: Indole Formation versus α‐Arylation.
Authors: Bai Yue‐Xia , Ping Da‐Wei , Little R. Daniel , Tian Hong‐Yu , Hu Li‐Ming , Zeng Cheng‐Chu 
Published: June 2012

AbstractThe procedure works with cyclic voltammetry and constant current electrolysis methods.
ChemInform Abstract: Nickel‐Catalyzed Enantioselective Cross‐Couplings of Racemic Secondary Electrophiles that Bear an Oxygen Leaving Group.
Authors: Oelke Alexander J. , Sun Jianwei , Fu Gregory C. 
Published: June 2012

AbstractA variety of silyl‐substituted propargylic carbonates are coupled with arylzinc iodides in the presence of a nickel/chiral bis(oxazolinyl)pyridine catalyst to give the arylated alkynes with up to 93% enantioselectivity.
ChemInform Abstract: Regioselective Cycloaddition of 3‐Azetidinones and 3‐Oxetanones with Alkynes Through Nickel‐Catalyzed Carbon—Carbon Bond Activation.
Authors: Ho Kelvin Y. T. , Aissa Christophe 
Published: June 2012

AbstractThe title reaction affords pyridinones and pyranones, correspondingly, with good to modest regioselectivity in the case of unsymmetrically internal alkynes.
ChemInform Abstract: Merging Domino and Redox Chemistry: Stereoselective Access to Di‐ and Trisubstituted β,γ‐Unsaturated Acids and Esters.
Authors: Tejedor David , Mendez‐Abt Gabriela , Cotos Leandro , Garcia‐Tellado Fernando 
Published: June 2012

AbstractDepending on the solvent, MeOH or water, the microwave‐assisted rearrangement of propargyl vinyl ethers affords alkenes bearing a malonate unit, or an ester/free acid group at the allylic position.
ChemInform Abstract: Green Bromine: In situ Generated Catalyst for the Selective Oxidation of Alcohols Using H2O2 as a Benign Oxidant.
Authors: Joshi Girdhar , Patil Rajendra D. , Adimurthy Subbarayappa 
Published: June 2012

AbstractUnder acid activation, a 5:1 NaBr/NaBrO3 mixture in situ generates Br2/BrOH species which catalyze the oxidation of benzylic/secondary alcohols by H2O2 to the corresponding aldehydes/ketones.
ChemInform Abstract: Transformation of Amines to Oximes Using Heterogeneous Nanocrystalline Titanium(IV) Oxide as a Green Catalyst.
Authors: Kidwai Mazaahir , Bhardwaj Saurav 
Published: June 2012

AbstractOptimum reaction conditions (solvent, catalyst) are examined for the oxidation of amines to the corresponding oximes using H2O2.
ChemInform Abstract: Selective Alkylation of (Hetero)Aromatic Amines with Alcohols Catalyzed by a Ruthenium Pincer Complex.
Authors: Agrawal Santosh , Lenormand Maud , Martin‐Matute Belen 
Published: June 2012

AbstractThe lack of reactivity concerning aliphatic amines prevents polyalkylation, i.e.
ChemInform Abstract: Direct Regiospecific and Highly Enantioselective Intermolecular α‐Allylic Alkylation of Aldehydes by a Combination of Transition‐Metal and Chiral Amine Catalysts.
Authors: Afewerki Samson , Ibrahem Ismail , Rydfjord Jonas , Breistein Palle , Cordova Armando 
Published: June 2012

AbstractThe present allylic alkylation of various linear aldehydes (II), catalyzed by an achiral palladium complex and a chiral amine as co‐catalyst, gives the corresponding alcohols after in situ reduction with NaBH4.
ChemInform Abstract: Ti/Ni‐Based Multimetallic System for the Efficient Allylation of Carbonyl Compounds.
Authors: Martinez‐Peragon Angela , Millan Alba , Campana Araceli G. , Rodriguez‐Marquez Irene , Resa Sandra , Miguel Delia , Alvarez de Cienfuegos Luis , Cuerva Juan M. 
Published: June 2012

AbstractA mild system for the allylation of carbonyl compounds includes Ni/Ti or Pd/Ti and allyl carbonates as pronucleophiles.
ChemInform Abstract: 1,4‐Induction in Aldol Reactions of (Tertiary α′‐Alkoxy)methyl Ketones: Synthesis of the C8—C11 Stereotriad of ent‐Fostriecin.
Authors: Cowper Nicholas , Azzi Soula , Dupont‐Gaudet Kristina , Burch Jason D. 
Published: June 2012

AbstractA general diastereoselective aldol condensation using a tertiary α′‐alkoxy group as the sterochemical control element is developed.