bluuebunny/crossref_metadata_2025_split huggingface dataset:
The influence of cerebellum on visual selective attention in patients with multiple lacunar cerebral infarction and its neuromodulatory mechanisms
Authors: Yuan Xiaodong , Duan Liqin , Ou Ya , Ling Qirong , Wang Jing , Zhang Jian , Cao Lingyun , Qian Hongchun , Zhang Pingshu 
Published: April 2024

ObjectiveThis study aims to investigate the influence of the cerebellum on visual selective attention function and its neuromodulatory mechanism in patients with multiple lacunar cerebral infarction (MLCI).MethodsA retrospective analysis was conducted on 210 patients admitted with MLCI from January 2016 to May 2022. Analyzed the electrophysiological characteristics of the P3a and P3b components of vision in both groups, as well as source reconstruction simulations of dipole activation in the brains of the two groups, and analyzed the brain regions with differences in activation strength between the two groups.ResultsThis study found that there was no significant difference in peak amplitude between the two groups, but compared with the control group, the peak latency of the case group was significantly prolonged. Specifically, the P3a peak latency induced by the novel stimulus was longer than that induced by the target stimulus P3b peak latency. Source reconstruction results showed decreased and increased activation in several brain regions in the case group compared to the control group.ConclusionThe study suggests that the impairment of distracted attention capture is more pronounced in patients with MLCI. The cerebellum indirectly influences the ventral and dorsal frontoparietal attention networks by modulating the levels of excitation and inhibition within the cerebral cortex of the attention network. This may represent a potential mechanism through which the cerebellum regulates visual selective attention information in MLCI patients.
Microwave ablation for painful chest wall metastases from gastrointestinal stromal tumor: a case report
Authors: Wang Shishi , Wang Lu , Li Tingting , Li Yuan , Zhuang Min , Lu Man 
Published: April 2024

BackgroundGastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the digestive tract, with the potential to metastasize. Metastases to bone and soft tissue are more frequent in advanced cases, where targeted therapy is the standard treatment. However, around 10–15% of patients develop disease progression despite treatment. Studies have shown the efficacy of ablation in managing bone and soft tissue metastases (1, 2), but there are no reports of ablation for treating GIST bone or soft tissue metastases.Case presentationIn 2022, a 58-year-old man complaining of left back pain was admitted to Sichuan Cancer Hospital. He had undergone radical resection of the primary gastric GIST and vertebral metastases in 2014 and 2018, respectively. In 2019, rib metastases still occurred despite the use of targeted therapy. During the course of radiotherapy, targeted therapy, and immunotherapy, he experienced persistent chest wall pain. In addition, new lesions occurred in the lungs and chest wall in 2022. After a thorough assessment, microwave ablation (MWA) was recommended in response to his demand for immediate pain relief. The large rib metastasis constricted the spleen, so we completed the ablation in two sessions to reduce the risk of complications. He had 17 months of follow-up until September 2023, during which time his discomfort was considerably reduced.ConclusionFor GIST patients with soft tissue and bone metastases, MWA may offer substantial immediate pain alleviation. When other treatment procedures fail to achieve adequate efficacy, it provides an option.
Predicting histologic grades for pancreatic neuroendocrine tumors by radiologic image-based artificial intelligence: a systematic review and meta-analysis
Authors: Yan Qian , Chen Yubin , Liu Chunsheng , Shi Hexian , Han Mingqian , Wu Zelong , Huang Shanzhou , Zhang Chuanzhao , Hou Baohua 
Published: April 2024

BackgroundAccurate detection of the histological grade of pancreatic neuroendocrine tumors (PNETs) is important for patients’ prognoses and treatment. Here, we investigated the performance of radiological image-based artificial intelligence (AI) models in predicting histological grades using meta-analysis.MethodA systematic literature search was performed for studies published before September 2023. Study characteristics and diagnostic measures were extracted. Estimates were pooled using random-effects meta-analysis. Evaluation of risk of bias was performed by the QUADAS-2 tool.ResultsA total of 26 studies were included, 20 of which met the meta-analysis criteria. We found that the AI-based models had high area under the curve (AUC) values and showed moderate predictive value. The pooled distinguishing abilities between different grades of PNETs were 0.89 [0.84-0.90]. By performing subgroup analysis, we found that the radiomics feature-only models had a predictive value of 0.90 [0.87-0.92] with I2 = 89.91%, while the pooled AUC value of the combined group was 0.81 [0.77-0.84] with I2 = 41.54%. The validation group had a pooled AUC of 0.84 [0.81-0.87] without heterogenicity, whereas the validation-free group had high heterogenicity (I2 = 91.65%, P=0.000). The machine learning group had a pooled AUC of 0.83 [0.80-0.86] with I2 = 82.28%.ConclusionAI can be considered as a potential tool to detect histological PNETs grades. Sample diversity, lack of external validation, imaging modalities, inconsistent radiomics feature extraction across platforms, different modeling algorithms and software choices were sources of heterogeneity. Standardized imaging, transparent statistical methodologies for feature selection and model development are still needed in the future to achieve the transformation of radiomics results into clinical applications.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42022341852.
The safety and use of perioperative dexamethasone in the perioperative management of primary sporadic supratentorial meningiomas
Authors: Arlt Felix , Basaran Alim Emre , Vogel Markus , Vychopen Martin , Seidel Clemens , Barrantes-Freer Alonso , Güresir Erdem , Wach Johannes 
Published: April 2024

ObjectiveDespite the lack of prospective evidence for the perioperative use of dexamethasone in meningioma surgery, its use is well established in the daily routine of several centers. The present study evaluates the effect of dexamethasone on postoperative complications, peritumoral T2/FLAIR hyperintensity, and progression-free survival in patients with supratentorial meningiomas undergoing resection.MethodsA total of 148 patients who underwent resection of a primary sporadic supratentorial meningioma at the authors’ institution between 2018 and 2020 were included in this retrospective cohort. Safety criteria were side effects of dexamethasone (e.g. hyperglycemia), surgical morbidities, length of stay, and mortality. The individual Karnofsky Performance Scales (KPS) were evaluated regarding the individual development and the delta of KPS at 3- and 12-months compared to baseline KPS was calculated. Longitudinal assessment of the peritumoral T2-/FLAIR hyperintensity changes was performed.ResultsThe use of both pre- and postoperative dexamethasone did not influence the incidence rates of wound infections, infarctions, postoperative seizures, pulmonary embolism, postoperative hemorrhage, mortality, length of stay, new-onset hyperglycemia and new neurological deficits. Perioperative Dexamethasone use was associated with an improved Karnofsky performance development at 3- (delta of KPS 3.3 vs. -1.9, p=0.001) and 12-months (delta of KPS 3.8 vs. -1.1, p=0.008) compared to the preoperative Karnofsky performance status. Multivariable analysis revealed that perioperative dexamethasone use enhances the KPS improvement (OR: 3.65, 95% CI: 1.01-13.18, p=0.048). Persistent peritumoral T2/FLAIR hyperintensity changes were observed in 35 cases of 70 patients with available follow-up images and a baseline edema (50.0%). Perioperative dexamethasone use enhanced the reduction of the preoperative peritumoral T2-/FLAIR hyperintensity changes (mean reduction of maximum diameter: 1.8 cm vs. 1.1 cm, p=0.023). Perioperative dexamethasone use was independently associated with a lower risk for persistent peritumoral T2-/FLAIR hyperintensity changes (OR: 3.77, 95% CI: 1.05-13.54, p=0.042) The perioperative use of dexamethasone did not influence the progression-free survival time in Simpson grade I or II resected WHO grade 1 meningiomas (log-rank test: p=0.27).ConclusionPerioperative dexamethasone use seems to be safe in surgery for primary supratentorial meningiomas. Dexamethasone use might enhance the functionality by reducing postoperative peritumoral T2-/FLAIR hyperintensities. These findings highlight the need for prospective data.
Adapting a dyadic exercise program to be culturally relevant for Hispanic men with prostate cancer using community engagement studio: a brief report
Authors: Skiba Meghan B. , Badger Terry A. , Garcia David O. , Chilton Floyd H. , Winters-Stone Kerri M. 
Published: April 2024

BackgroundCancer disparities exist for Hispanic men with prostate cancer and their caregivers that could be reduced through exercise. Exercising Together© is a six-month, evidence-based dyadic resistance training program that promotes teamwork between prostate cancer survivors and their spouses to improve physical, mental, and relational health outcomes. The purpose of this study was to elicit feedback and recommendations from stakeholders on the Exercising Together© intervention to inform the cultural adaptation of this program for Hispanic men with prostate cancer.MethodsWe conducted a virtual Community Engagement Studio (V-CES) with community expert stakeholders representing the Hispanic and cancer care communities in Southern Arizona. The V-CES process included orientation, presentation of the research, guided discussion, and evaluation. The V-CES was audio recorded, transcribed, and rapidly analyzed to identify actionable feedback and contextual adaptations.ResultsNine stakeholders (6/9 male; 5/9 Hispanic) completed all V-CES activities. Through stakeholder engagement and feedback from the V-CES, adaptations to the original Exercising Together© intervention included: (1) inclusion of the cancer survivor’s identified caregiver, who may not be a spouse; (2) availability in English and Spanish; (3) shortening the intervention to 3 months; (4) remote delivery of the intervention; and (5) incorporation of low burden procedures.ConclusionFindings from our V-CES informed the adaptation of a culturally relevant dyadic progressive resistance training program for Hispanic men with prostate cancer and their caregivers.
The impact of family residence structure on adolescents’ non-cognitive abilities: evidence from China
Authors: Tang Bin , Xiao Siyi , Zhang Yi , Liu Siyan , Lin Xiaoli , Liu Han 
Published: April 2024

PurposeThe family residence structure serves as a crucial pathway through which the family environment influences adolescents’ development.MethodsDrawing on nationally representative data, this study employs multiple linear regression models and propensity score matching to examine the impact of various family residence structures on adolescents’ non-cognitive abilities. Causal identification is achieved through propensity score matching, while robustness is assessed using methods such as augmented inverse probability weighting and placebo tests. Heterogeneity analysis is conducted based on gender and household registration, aiming to explore the mechanisms by which family residence structure affects adolescents’ non-cognitive abilities.ResultsThe findings indicate that compared to two-parent co-residence households, three-generation co-residence families have significantly positive effects on emotional stability, conscientiousness, and agreeableness among adolescents. In contrast, skip-generation coresidence families exhibit significant negative effects on emotional stability and agreeableness in adolescents. Further investigation into the underlying mechanisms reveals that parental involvement and family socioeconomic status within three-generation co-residence families positively influence adolescents’ non-cognitive abilities.ConclusionThis study highlights the importance of considering grandparents’ role in adolescent growth and advocates for policy recommendations focusing on enhancing non-cognitive abilities in adolescents from skip-generation co-residence families.
Determinants of central obesity in children and adolescents and associated complications in South Africa: a systematic review
Authors: Ntimana Cairo Bruce , Seakamela Kagiso Peace , Mashaba Reneilwe Given , Maimela Eric 
Published: April 2024

BackgroundCentral obesity in children is a global health concern associated with cardiovascular risk factors. In 2019 the World Obesity Federation predicted that in 2025, 206 million children and adolescents aged 5 to 19 will be obese, and the number is estimated to reach 254 million by 2030. There is limited literature on the factors that are associated with the development of central obesity in children. We report a systematic review, aimed to describe the current literature on determinants of central obesity and its associated health outcomes in children and adolescents in the South African population.MethodsWe searched for peer-reviewed studies in Google Scholar, PubMed, and Science Direct search engines, and about seven studies were included. This systematic review has been registered with the International Prospective Register of Systematic Reviews (PROSPERO) (Registration number: CRD42023457012). This systematic review was conducted and reported according to an updated version of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The quality of the included studies was assessed by following guidelines from the Newcastle-Ottawa Scale (NOS). The method considered three main domains: selection, comparability, and outcome across different study designs.ResultsThe prevalence of central obesity in children and adolescents by waist-to-height ratio (WHtR) ranged from 2.0 to 41.0%; waist-to-hip [WHR ranged from 10 to 25%; waist circumference (WC) ranged from 9 to 35%]. Central obesity was associated with age, physical inactivity, gender socio, and demographic profiles of the household. Central obesity in children was associated with cardiovascular diseases and mental health issues.ConclusionCentral obesity in children and adolescents was determined by gender, pubertal development, and age of the parents, households with high socioeconomic status, dietary practices, and overweight/obesity. Given the high prevalence of central obesity in children which can ultimately result in cardiometabolic diseases, cardiovascular risk factors, and mental health issues. This highlights the need for systems, jointly initiated by healthcare providers, policymakers, and the general society aimed at reducing the burden of central obesity such as introducing children and adolescents to health-promoting lifestyles.
PELATIHAN SIMULATOR APLIKASI SMARTCLASS ROOM BERBASIS IoT UNTUK GURU- GURU SMK NASIONAL BANDUNG
Authors: Ema Ema , Prajna Deshanta Ibnugraha  , Muhammad Ikhsan Sani  , Nina Hendrarini  
Published: April 2024

Revitalization of vocational schools is the core of the mandate of Presidential Instruction No. 9/2016 on Revitalization of Vocational High Schools (SMK). Vocational Education is education that refers to the mastery of applied expertise in a particular field. Students will be equipped with theory and also the implementation of learning in the form of practice.
The Ministry of Education and Culture adjusts and develops the vocational education curriculum and adjusts it to be demand-driven so that the business world and the industrial world (DUDI) are more actively involved in the vocational education process in SMK. This IoT-based Smart class Room Application Simulator abdimas program aims to provide insight and increase competence for SMK teachers so that they can work and implement this knowledge to their students. The results of this abdimas feedback are 60% agree and 40% strongly agree. This shows that this abdimas program has succeeded in providing benefits to SMK teachers.
Algorithm of Order 3 Matrix in a Chosen Basis
Authors: Pozinkevych Ruslan 
Published: April 2024

The aim of our research is to establish relationship between linearly
independent vectors and the R Space The means for
that are going to be taken from Balanced Ternary analysis e.g. triplets
with entries (-1,0,1) This is not going to be any specific vector, for
instance (-1,0,1) It’s going to be rather a Coordinate system with 8
quadrants and directional vectors The novelty of the proposed research
lies in the fact that unlike traditional Cartesian system-vector basis
our system uses 8 vectors which are at the same time a polyvector (Boas)
We may define it as a multiple of the type: ∑ (i=-1)^1∑ (j=-1)^1
∑ (k=-1)^1〖(i,j,k)〗
IMPLEMENTASI KEBIJAKAN PEMENUHAN HAK ORANG DENGAN GANGGUAN JIWA DI KABUPATEN HULU SUNGAI UTARA
Authors: Affrian Reno 
Published: April 2024

Mental disorders are a collection of abnormal conditions, both those related to physical and mental. Local governments are responsible for fulfilling the rights of people with mental disorders, the right to get treatment and care and rehabilitation in order to obtain complete recovery. Based on the results of the research that has been carried out it can be concluded that: Implementation of the fulfillment of the rights of people with mental disorders has not fully gone well, it is seen from the resources to run mental health services are not fully adequate, and there are still problems related to the economic, social and political. Factors that influence the Implementation of the Fulfillment of the Rights of People with Mental Disorders in Hulu Sungai Utara Regency are influenced by several factors 1. Resources 2. Economic, Social and Political Environment
PENERAPAN ASPEK RASIONALITAS DALAM PEMILU 2019 (STUDI TERHADAP TINGKAT PARTISIPASI POLITIK ODGJ DI KABUPATEN HULU SUNGAI UTARA)
Authors: Lesmana Budi 
Published: April 2024

Election as a means of popular sovereignty is a vehicle for every citizen who has the right to choose to use his political rights and voice in choosing a leader. Without exception, based on the provisions in the legislation, every citizen can use this right.
In the implementation of the 2019 Election, the KPU strives maximally to accommodate all citizens who have the right to vote in the DPT. Repairs made many times are as an effort to increase voter involvement in elections.
One voter group that is a public concern and discourse is mental accessibility or more commonly referred to as People with Mental Disorder (ODGJ) who voted in the 2019 election. Outside the context that these mentally ill people are under forgiveness according to civil law, the constitution itself basically gives the same rights to people who have mental illness to choose. Even in the Election Law itself there is no prohibition explicitly governing this. This means that mentally ill people also have the right to exercise their right to vote. Not all mentally ill people have the awareness to choose. Of course, if there are certain conditions that are allowed to choose.
But how is the implementation of the business and rules in the field as an effort to increase voter participation by the organizers? And what is important is whether the application of direct, general, free, confidential and fair election principles can also be felt by ODGJ voters. Can their rights be used, but only choose formalities without secrecy. Don't let the voting rights of citizens with certain conditions be given an opportunity to commit fraud in the election. Fraud is detrimental to the voting rights of people who have mental disorders because it is considered easy to be cheated.
ANALISIS DESKRIPTIF KEPEMIMPINAN BIDANG BINA PENDIDIKAN DASAR (DIKDAS) DI DINAS PENDIDIKAN BALANGAN
Authors: Setiawan Irza 
Published: April 2024

A leader must have a good competence to successfully bring the organization for its intended purpose. If a led organization is engaged in education field, of course a leader must also have a competence that qualified both skill, science, and experience in the field of education. However, related to that, it also found some problems about leadership, namely the leader is less exemplary discipline, less competent in the field, less provide guidance, less coordination and unable to make their own decisions. Based on the above things, this study aims to find out how the leadership in the field of basic education (DIKDAS) is, what factors affect the leadership in the field of basic education (DIKDAS), and what effort are being made to improve the leadership in the field of basic education (DIKDAS) at Dinas Pendidikan Balangan district. The location of research is at the office of Dinas Pendidikan Balangan district. The approach used is a qualitative approach with a qualitative description type. Data collection technique used are interviews, observation, and documentation. The source of data is amounted to 14 people. After the data collected, then analyzed through 3 stages, namely data editing, data presentation, and verification or drawing conclusion. The result of the research indicate that the leadership in the field of basic education (DIKDAS) has not been entirely good. This can be seen from the side of responsibility that is less independent as a leader and does not have the desire to excel. On the other hand, the leader in the field of basic education (DIKDAS) is considered to have capacity in the from of intelligence, speech and judgment ability. From the aspect of achievement is an appropriate bachelor degree and a quite estensive knowledge. From the aspect of responsibility is a quite good initiative, diligent, tenacious, and confident. From the aspect of participation, that is active, have high sociability, cooperative, and able to adjust. The factors that influence leadership are the expertise and employee loyalty to leader, education and training experience, and the leader’s intelligence. Then, the effort to improve the leadership is delegation of tasks to subordinates, the approach by the leadership to subordinates and training as well as discussion. The suggestions to improve the leadership in the field of basic education (DIKDAS) are the leaders need to be a motivator for subordinates, have the attitude of independence, one of them is able to make their own decisions that precarious, and have the desire to excel in order to spur achievement.