bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vitro antibacterial activity of nanoconjugated vancomycin against plasmid mediated intraspecies and interspecies transfer of vancomycin resistance
Authors: Chakraborty Subhankari Prasad , Pramanik Panchanan , Roy Somenath 
Published: October 2011

Abstract

Background: The aim of the present study was to observe the plasmid mediated intraspecies and interspecies transfer of vancomycin resistance, and possible antibacterial activity of nanoconjugated vancomycin against such resistant.

Methods: Plasmids were isolated from a chosen vancomycin resistant Staphylococcus aureus strain (MMC-17). The obtained 890 bp plasmid was then transferred to vancomycin sensitive S. aureus (MMC-6) and Escherichia coli (RGK 26) strains.

Results: The vancomycin sensitive S. aureus and E. coli developed vancomycin resistance. Plasmid analysis of the transformed MMC-6 and RGK 26 revealed that it contains 890 bp plasmid corresponding to the donor S. aureus, which may harbor the vanA gene. Nanoconjugated vancomycin shows its efficient drug action through transport of vancomycin into transformed MMC-6 and RGK 26.

Conclusions: Plasmid mediated intraspecies and interspecies transfer of vancomycin resistance is accomplished by the vanA gene. Nanoconjugated vancomycin shows effective drug delivery in plasmid mediated vancomycin resistance in S. aureus and E. coli.
Reducing Bloodstream Infections in Pediatric Rehabilitation Patients Receiving Parenteral Nutrition
Authors: Castello Frank Vincent , Maher Anne , Cable Gregory 
Published: October 2011

OBJECTIVE:
To report our quality improvement efforts to reduce total parenteral nutrition (TPN)-associated bloodstream infections, and the results of those efforts, during the period including the first quarter of 2004 through the third quarter of 2010.

METHODS:
A variant on failure modes and effect analysis and existing guidelines were used to develop and modify interventions. Effectiveness of the interventions was assessed by using a graphical depiction of interrupted time-series data on TPN-associated infections per 1000 TPN-days, aggregated across quarters within intervention periods.

RESULTS:
Although initial interventions yielded limited reductions in infection rates, it was not until the implementation of a multifaceted “maintenance intervention bundle” that rates strongly responded. After this key intervention revision, the TPN-associated infection rate decreased between implementation in the first quarter of 2008 from 26.1 to 4.8 per 1000 TPN-days during the 8 quarters aggregated comprising the first quarter of 2008 through the fourth quarter of 2009. The final addition of an alcohol-swab cap resulted in a reduction of rates to 0 for the first three-quarters of 2010.

CONCLUSIONS:
Our evidence suggests that iterative design/redesign of interventions using failure modes and effect analysis has directly reduced TPN-associated bloodstream infections.
Experimental Evidence of Super Densification of Adsorbed Hydrogen by in-situ Small Angle Neutron Scattering (SANS)
Authors: Saha Dipendu , He Lilin , Contescu Cristian I. , Gallego Nidia C. , Melnichenko Yuri B. 
Published: October 2011

ABSTRACTEntrapping hydrogen molecules within the nanopores of solid adsorbents serves as a unique alternative for on-board storing of hydrogen for transportation purposes. The key advantage of the physisorption process for hydrogen storage is the higher density values achieved with the adsorbed gas, compared to that of the compressed phase, translating into higher storage capacities at lower pressures. The necessary condition for effective adsorption is the presence of narrow micropores of < 2 nm in width which provide the most suitable environment of hydrogen adsorption. Despite numerous theoretical calculations or indirect experimental estimations, there has not been a direct experimental measurement of the density of adsorbed hydrogen as a function of pressure and/or pore size. In the present study, we report on the use of in-situ small angle neutron scattering (SANS) to study the phase behavior of hydrogen confined in narrow micropores. We provide for the first time direct experimental measurements of the effect of pore size and pressure on hydrogen adsorbed on a polyfurfuryl alcohol-derived activated carbon (PFAC), at room temperature and pressures up to 207 bar. SANS studies were carried out at the General-Purpose Small-Angle Neutron Scattering spectrometer of the High Flux Isotope Reactor at Oak Ridge National Laboratory. The measurements covered the Q-range from 0.01 to 0.8 Å-1, covering the pores in the range of 9 to 34 Å of the PFAC material. Initial results suggest that the density of adsorbed hydrogen is higher than the density of bulk hydrogen gas and increases with decreasing pore size.
Characterization of AgInSbTe-SiO2 Nanocomposite Thin Film for Hydrogen Gas Sensor Applications
Authors: Wang Ching-Hung , Chiang Kuo-Chang , Hsieh Tsung-Eong 
Published: October 2011

ABSTRACTHydrogen (H2) sensing property of AgInSbTe (AIST)-SiO2 nanocomposite thin film prepared by target-attachment sputtering method was investigated in this work. The sample subjected to a 400°C-annealing for 90 sec exhibits a significant sensitivity (58.9 %) and short response time (75 sec) upon the exposure to an ambient containing 200 ppm H2 at 75°C. The gas sensing capability is ascribed to the presence of antimony oxides, e.g., Sb2O3 and Sb2O5, in nanocomposite layer which provide the charge carriers for sensing reactions. Moreover, the high specific-surface-area (SSA) feature of AIST nanocrystals in nanocomoposite layer provided numerous sites for reduction/oxidation reactions and thus a good H2 gas sensing property can be achieved.
Analysis of Hydrogen Adsorption in Microporous Adsorbents at Room Temperature and High Pressures
Authors: Voskuilen Tyler G. , Pourpoint Timothée L. 
Published: October 2011

ABSTRACTAn experimental study of hydrogen adsorption in a variety of high-surface area adsorbent materials has been conducted at room temperature and pressures up to 500 bar on high surface area activated carbons, zeolite templated carbons (ZTC), and metal organic frameworks (MOFs). For all materials, excess hydrogen adsorption isotherms were measured up to 500 bar and have been analyzed in terms of the BET surface area and pore size distribution. The materials were also evaluated for their increase in hydrogen storage density over compressed gas. It was determined that, due to the lower excess adsorption and skeletal densities for the microstructured materials, MOF-177 and ZTC have worse storage densities than compressed gas at most pressures, even when assuming a bed compaction factor of two, while the activated carbons offer marginal increases in storage density over the pressure range investigated.
Role of extracellular matrix and prolactin in functional differentiation of bovine BME-UV1 mammary epithelial cells
Authors: Kozłowski M. , Wilczak J. , Motyl T. , Gajewska M. 
Published: October 2011

Role of extracellular matrix and prolactin in functional differentiation of bovine BME-UV1 mammary epithelial cells
Interactions between extracellular matrix (ECM) and epithelial cells are necessary for proper organisation and function of the epithelium. In the present study we show that bovine mammary epithelial cell line BME-UV1 cultured on ECM components, commercially available as Matrigel™, constitutes a good model for studying mechanisms controlling functional differentiation of the bovine mammary gland. In contact with Matrigel BME-UV1 cells induce apicobasal polarity, and within 16 days form three dimensional (3D) acinar structures with a centrally localized hollow lumen, which structurally resemble mammary alveoli present in the functionally active mammary gland. We have shown that the 3D culture system enables a high expression and proper localisation of integrin receptors and tight junction proteins in BME-UV1 cells to be induced. This effect was not obtained in cells grown in the classical 2D culture system on plastic. Moreover, ECM highly stimulated the synthesis of one of the major milk proteins, β-casein, even in the absence of prolactin. Our results show that contact with ECM plays an important role in the lactogenic activity of bovine MECs, however, prolactin is necessary for the efficient secretion of milk proteins.
Magnetic resonance imaging of selected limb joints in dogs
Authors: Adamiak Z. , Jaskólska M. , Matyjasik H. , Pomianowski A. , Kwiatkowska M. 
Published: October 2011

Magnetic resonance imaging of selected limb joints in dogs
The presented paper presents updated information concerning magnetic resonance imaging (MRI) of shoulder joint, elbow joint and knee joint in dogs. It describes indications, planes, standard sequences, slice thickness to perform MRI examination of above mentioned joints. Besides general information about basic physics use in magnetic resonance imaging, and practical information about magnetic resonance and it usage in orthopedic examination are given.
Thermoelectric transport properties of an apparent Fermi liquid: Relation to an analytic anomaly in the density of states and application to hole‐doped delafossites
Authors: Kremer S. , Frésard R. 
Published: October 2011

AbstractThrough the motivation of the recent discovery of dispersionless regions in the band structure of the delafossites, a model density of states of free fermions including a d anomaly is studied. The resulting temperature dependence of the chemical potential is obtained both exactly and by different approximation schemes which are then discussed thoroughly. This includes the introduction of an approximation of the polylogarithm difference which is capable of accessing a parameter range neither covered by Sommerfeld expansion nor by Boltzmann approximation. It is found that the Fermi temperature and several other temperature scales may be very low, giving rise to experimentally observable behaviours differing from the one described by Fermi liquid theory. In particular, two kinds of apparent Fermi liquid behaviour emerge at intermediate temperatures. This behaviour is related to recent transport data reported for CuCr1‐xMgxO2 [A. Maignan et al., Solid State Commun. 149, 962 (2009)] and CuRh1‐xMgxO2 [A. Maignan et al., Phys. Rev. B 80, 115103 (2009)] by means of the temperature independent correlation functions ratio approximation. In this way an effective density of states as well as the effective charge carrier density of these materials are determined. Furthermore, conclusions about the specific heat of the latter material are drawn which presents particular effects of the analytical anomaly.
Degradation behaviors of linear low‐density polyethylene and poly(L‐lactic acid) blends
Authors: Singh Gursewak , Kaur Navleen , Bhunia Haripada , Bajpai Pramod K. , Mandal Uttam K. 
Published: October 2011

AbstractIn this study, the degradability of linear low‐density polyethylene (LLDPE) and poly(L‐lactic acid) (PLLA) blend films under controlled composting conditions was investigated according to modified ASTM D 5338 (2003). Differential scanning calorimetry, X‐ray diffraction, and Fourier transform infrared spectroscopy were used to determine the thermal and morphological properties of the plastic films. LLDPE 80 (80 wt % LLDPE and 20 wt % PLLA) degraded faster than grafted low‐density polyethylene–maleic anhydride (M‐g‐L) 80/4 (80 wt % LLDPE, 20 wt % PLLA, and 4 phr compatibilizer) and pure LLDPE (LLDPE 100). The mechanical properties and weight changes were determined after composting. The tensile strength of LLDPE 100, LLDPE 80, and M‐g‐L 80/4 decreased by 20, 54, and 35%, respectively. The films, as a result of degradation, exhibited a decrease in their mass. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Investigation of the rheological behavior of titanium dioxide pigmented acrylonitrile–butadiene–styrene polymer
Authors: Taghinejad Soheil Farshbaf , Behrouzi Mina , Asiaban Saeed 
Published: October 2011

AbstractTitanium dioxide (TiO2) pigments may be surface‐modified by hydrous oxides, such as alumina (e.g., Cristal 134) or by organic compounds, such as organophosphate (e.g., Tiona 188). In this investigation, the effects of these pigments on the rheological properties of acrylonitrile–butadiene–styrene (ABS) polymer were investigated. With the oscillatory rheometry method in the linear viscoelastic region, the storage and loss moduli versus frequency graph of ABS in the molten state showed two crossover points (COPs) when the surface of the ABS components, that is, poly(styrene‐stat‐acrylonitrile) and poly[(styrene‐stat‐acrylonitrile)‐graft‐polybutadiene] or g‐ABS, had good interaction. The first COPs increased when the TiO2 content rose to 0.5 and 1.5% in Tiona 188 and Cristal 134 pigmented ABS samples, respectively. With the addition of TiO2 up to these contents, the polymer–pigment interaction becomes stronger so that the dispersion of the pigments was good. With increasing TiO2, the first COPs dramatically decreased because of agglomeration of the pigments. The shifting of the first COP may be applied as a criterion to specify the dispersion of TiO2 particles in the ABS matrix. Scanning electron micrographs showed that the pigments had no effect on the size of the polybutadiene particles. Also, transmission electron micrographs proved that agglomerates of Tiona 188 and Cristal 134 particles were formed above 0.5 and 1.5% TiO2 contents, respectively. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Polysilazane‐based heat‐ and oxidation‐resistant coatings on carbon fibers
Authors: Shayed M. A. , Hund R. D. , Cherif C. 
Published: October 2011

AbstractCarbon fibers must be protected from a high‐temperature oxidizing environment because, at approximately 500°C and above, the fibers exhibit reduced mass and strength stability. The fibers can be protected by the application of thermal coatings, which simultaneously improve the adhesive properties of the carbon fibers in the composite materials. Polysilazanes are a new family of heat‐resistant polymer coatings that are converted into silicone carbide or silicone nitride ceramic structures at high temperatures. The converted ceramics are resistant to the effects of high temperatures. In this research work, polysilazane‐based coatings were applied to carbon filament (CF) rovings with the dip‐coating method. Tensile testing at room temperature and under thermal stress was carried out to assess the mechanical and thermomechanical properties of both coated and uncoated rovings. Scanning electron microscopy and energy‐dispersive X‐ray analysis were performed to evaluate the surface topographical properties of the coated and uncoated rovings. Thermogravimetric analysis was executed to determine the thermal stability of the polymer coatings. The coating performance on the CF rovings was determined by assessment of the test results obtained. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Pilocarpine‐loaded poly(DL‐lactic‐co‐glycolic acid) nanoparticles as potential candidates for controlled drug delivery with enhanced ocular pharmacological response
Authors: Nair K. Lekha , Vidyanand S. , James Jackson , Kumar G. S. Vinod 
Published: October 2011

AbstractThe poor corneal residence time of pilocarpine, an alkaloid extracted from the leaves of the Jaborandi plant, limits its ocular application. The aim of this study was to develop, characterize, and evaluate the potential of pilocarpine entrapped by poly(DL‐lactic‐co‐glycolic acid) (PLGA) nanoparticle carriers for ocular drug delivery. Pilocarpine‐loaded nanoparticles were prepared with a double‐emulsion (water in oil in water) method and characterized with transmission electron microscopy and X‐ray diffraction analysis. The nanoparticles exhibited an average size of 82.7 nm with an encapsulation efficiency of 57%. Stability studies showed the absence of agglomeration and constancy in the amount of drug entrapped; this indicated the solidity of these particles for long‐term use. The in vitro release studies conducted in simulated tear fluid showed the sustained release of pilocarpine. In vivo evaluation of the nanoparticles was done in a rabbit model with a miosis assay and compared to an equal dose of commercially available eye drops of pilocarpine (Pilocar drops). The in vivo miosis studies showed that the duration of miotic response increased by 40% for the nanoparticles and produced an almost 68% increase in total miotic response when compared to the eye drops. In conclusion, this study clearly demonstrated the potential of pilocarpine‐loaded PLGA nanoparticles for multiplying the therapeutic effect of ophthalmic drug delivery with enhanced bioavailability and pharmacological response. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Thermal Behaviors of 2‐(Dinitromethylene)‐1,3‐diazacycloheptane (DNDH)
Authors: Lü Lei , Xu Kangzhen , Wang Gang , Luo Jinan , Song Jirong , Wang Bozhou , Zhao Fengqi 
Published: October 2011

Abstract2‐(Dinitromethylene)‐1,3‐diazacycloheptane (DNDH) was prepared by the reaction of 1,1‐diamino‐2,2‐dinitroethylene (FOX‐7) with 1,4‐diaminoethane in NMP. Thermal decomposition behavior of DNDH was studied under the non‐isothermal conditions with DSC method, and presents only one intensely exothermic decomposition process. The kinetic equation of the decomposition reaction is dα/dT=1033.88×3α2/3exp(−3.353×105/RT)/β. The critical temperature of thermal explosion is 215.97°C. Specific heat capacity of DNDH was studied with micro‐DSC method and theoretical calculation method, and the molar heat capacity is 215.40 J·mol−1·K−1 at 298.15 K. Adiabatic time‐to‐explosion was calculated to be 92.07 s. DNDH has same thermal stability to FOX‐7.
New Synthetic Route of Two Active Isomeric Metabolites of Erlotinib and Their Bioactivity Studies against Several Tumor Cell Lines
Authors: Li Hanqing , Li Mengyao , Li Zaiquan , Li Liang , Bi Shanshan , Deng Chenhui , Chen Rui , Zhou Tianyan , Lu Wei 
Published: October 2011

AbstractThe synthesis and differential antiproliferative activity of two active isomeric metabolites of erlotinib were investigated. This synthetic process had demonstrated to avoid the unstable 4‐chloroquinazoline intermediates and long procedures. New intermediates and final compounds were identified by 1H NMR, 13C NMR and ESI‐TOF MS, and their purities were determined by high performance liquid chromatography. In vitroproliferative assay indicated that these two metabolites possessed antiproliferative activity against some conventional tumor cell lines and EGFR tyrosine kinase over‐expression tumor cell lines as compared to erlotinib control, and their antitumor activity in cellular level was first reported here.
One‐pot Combinatorial Synthesis of Benzo[4,5]imidazo‐[1,2‐a]thiopyrano[3,4‐d]pyrimidin‐4(3H)‐one Derivatives
Authors: Shen Shide , Zhang Honghong , Yang Weihua , Yu Chenxia , Yao Changsheng 
Published: October 2011

AbstractA series of novel fused tetracyclic benzo[4,5]imidazo[1,2‐a]thiopyrano[3,4‐d]pyrimidin‐4(3H)‐one derivatives were synthesized via the reaction of aryl aldehyde, 2H‐thiopyran‐3,5(4H,6H)‐dione, and 1H‐benzo[d]imidazol‐2‐amine in glacial acetic acid. This protocol features mild reaction conditions, high yields and short reaction time.
A Tri‐µ‐O‐S‐O Manganese Dimer: Synthesis, Structral and EPR Study
Authors: Bi Yangang , Chen Yuyou , Lu Xiaoming 
Published: October 2011

Abstract A Tri‐µ‐O‐S‐O coordinative manganese dimer: [Mn2(SO4)2(phen)4]·CH3OH (phen1,10‐phenanthroline) (1) was yielded by the reaction of 1,10‐phenanthroline and MnSO4·H2O in a mixed solvent of methanol and acetonitrile under room temperature and was structurally characterized. Single crystal analysis shows that complex 1 has polymeric structure based on binuclear Mn(II) units bridged by O‐S‐O groups of two SO42− anion. The UV spectrum of the complex clarifies that each metal‐organic building unit parallels with each other through the Π‐Π interactions of face‐to‐face separations of two 1,10‐phen planes among the complex, forming a layered structure. And the electronic paramagnetic resonance (EPR) signal clearly indicates that those manganese atoms in complex 1 are in +2 oxidation states.
Synthesis and Opto‐electronic Properties of a Red‐Emitting Heteroleptic Platinum Complex Using Pyrazol‐based Diketone Derivative as Ancillary Ligand
Authors: Deng Jiyong , Wang Yafei , Li Xiaoshuang , Ni Meijun , Liu Ming , Liu Yu , Lei Gangtie , Zhu Meixiang , Zhu Weiguo 
Published: October 2011

AbstractA red‐emitting heteroleptic cyclometalated platinum(II) complex containing an ancillary ligand of pyrazol‐based diketone derivative was synthesized. Its optophysical and electroluminescent properties were studied. Compared to the reported (piq)Pt(acac) complex, this platinum(II) complex exhibited a blue‐shifted UV absorption band at 300–450 nm, a low LUMO energy level and improved electroluminescent property. Using this platinum(II) complex as a single doping emitter and a blend of ploy(9,9‐dioctylfluorene) and 2‐tert‐butylphenyl‐5‐phenyl‐1,3,4‐oxadiazole as a host matrix, the fabricated polymer light‐emitting devices displayed saturated red emission with a peak at 648 nm and a shoulder at 601 nm. Furthermore, the emission quenching of the platinum(II) complex was significantly suppressed in these devices at high current density due to an introduction of the non‐planar pyrazol group into the ancillary ligand.
Encapsulation Chalcogen Anions in Perfluorinated Silicon Fullerene: X2−@Si20F20 (X=O, S, Se)
Authors: Wang Hong , Wu Lin 
Published: October 2011

AbstractThe structures and stabilities of cage Si20F20 and its endohedral complexes X2−@Si20F20 (X=O, S, Se) were determined at the B3LYP/6‐31G(d) levels of density functional theory (DFT). It is found that the adiabatic electron affinity (EAad) of host cage Si20F20 (Ih) is higher than that of isolated O atom (4.24 vs. 1.46 eV). This suggests the Si20F20 cage can selectively trap and stabilize the capsulated spherical anions. The calculations predict that X=S and Se are nearly located at the center of the cage, and O dramatically deviates from the center in C3v symmetry. Moreover, the corresponding X2−@Si20F20 complexes have more negative inclusion energies (ΔEinc) and thermodynamic parameters (ΔZ) than X2−@C20F20. The amount of charge that is being transferred from the encapsulated anions to the cage increases with the atomic radius, i.e., from O2− (ca. 45%), S2− (ca. 51%) to Se2− (ca. 59%), and such a novel model of cage may have practical uses as potential and electrical building units of nanoscale materials.
Synthesis, Photophysical Properties of Tribranched Chromophores Based on 1,3,5‐Triazine Core and Different Electro‐donating End‐groups
Authors: Liu Li , Huang Wei , Shi Jieping , Lü Changgui , Cui Yiping , Lu Guo‐Yuan 
Published: October 2011

AbstractThree two‐photon absorption (TPA) tribranched chromophores were successfully prepared, in which 1,3,5‐triazine is been as electron deficient core, 1,4‐phenylenedivinylene as conjugated bridge, 3,4‐ethylenedioxythiophene (EDOT) (T1), N‐methylpyrrole (T2) or triphenylamine (T3) as electron‐donating end‐groups. Their photophysical properties were studied by absorption, one‐ and two‐photon fluorescence and TPA cross‐section determination. The nonlinear transmission (NLT) measurement in femtoseconds (fs) regime at 800 nm indicates that TPA cross‐section (2 values of T1, T2 and T3 with extended Π‐conjugated bridge are much larger than the corresponding chromophore T4 with a short length bridge, and TPA cross‐section of T1 with end‐groups EDOT exhibits a remarkable enhancement compared with T2 and T3 having the same length Π‐system. The chromophores T1, T2 and T3 show also remarkable up‐converted luminescence and optical limiting activity.