bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives of people experiencing homelessness with recent non-fatal street drug overdose on the Pharmacist and Homeless Outreach Engagement and Non-medical Independent prescribing Rx (PHOENIx) intervention
Authors: Farmer Natalia , McPherson Andrew , Thomson Jim , Lowrie Richard 
Published: May 2024

Introduction
In Scotland, a third of all deaths of people experiencing homelessness (PExH) are street-drug-related, and less than half of their multiple physical- and mental health conditions are treated. New, holistic interventions are required to address these health inequalities. PHOENIx (Pharmacist Homeless Outreach Engagement and Non-medical Independent prescribing Rx) is delivered on outreach by National Health Service (NHS) pharmacist independent prescribers in partnership with third sector homelessness charity workers. We describe participant’s perspectives of PHOENIx.

Methods
This study aims to understand experiences of the PHOENIx intervention by participants recruited into the active arm of a pilot randomised controlled trial (RCT). Semi-structured in-person interviews explored participants’ evaluation of the intervention. In this study, the four components (coherence, cognitive participation, collective action, reflexive monitoring) of the Normalisation Process Theory (NPT) framework underpinned data collection and analyses.

Results
We identified four themes that were interpreted within the NPT framework that describe participant evaluation of the PHOENIx intervention: differentiating the intervention from usual care (coherence), embedding connection and consistency in practice (cognitive participation), implementation of practical and emotional operational work (collective action), and lack of power and a commitment to long-term support (reflexive monitoring). Participants successfully engaged with the intervention. Facilitators for participant motivation included the relationship-based work created by the PHOENIx team. This included operational work to fulfil both the practical and emotional needs of participants. Barriers included concern regarding power imbalances within the sector, a lack of long-term support and the impact of the intervention concluding.

Conclusions
Findings identify and describe participants’ evaluations of the PHOENIx intervention. NPT is a theoretical framework facilitating understanding of experiences, highlighting both facilitators and barriers to sustained engagement and investment. Our findings inform future developments regarding a subsequent definitive RCT of PHOENIx, despite challenges brought about by challenging micro and macro-economic and political landscapes.
The clinical significance of long non-coding RNAs MALAT1 and CASC2 in the diagnosis of HCV-related hepatocellular carcinoma
Authors: Golam Rehab M. , Khalil Mahmoud A. F. , Shaker Olfat G. , Ahmed Tarek I. , Elguaad Mohamed K. Abd , Hassan Essam A. , El-Ansary Mahmoud R. M. , Ismail Ahmed , Kandil Yasser I. , Mohammed Osama A. , Doghish Ahmed S. 
Published: May 2024

Background
Globally, hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death due to a lack of early predictive and/or diagnostic tools. Thus, research for a new biomarker is important. LncRNAs play a functional role in target gene regulation and their deregulation is associated with several pathological conditions including HCC.

Objective
This study aimed to explore the diagnostic potential of two LncRNAs MALAT1 and CASC2 in HCC compared to the routinely used diagnostic biomarker.

Materials and methods
The current study is a case-control study carried out at Fayoum University Hospital and conducted on 89 individuals. The study included three groups of 36 HCC patients on top of HCV(HCC/HCV), 33 HCV patients, and 20 healthy volunteers as a control group. All study subjects were subjected to radiological examinations. The determination of CBC was performed by the automated counter and liver function tests by the enzymatic method were performed. In addition, HCV RNA quantification and the expression level of two LncRNAs (MALAT1 and CASC2) were performed by qRT-PCR.

Results
The results revealed a statistically significant difference between study groups regarding liver function tests with a higher mean in HCC/HCV group. Also, serum MALAT1 significantly up-regulated in HCV (11.2±2.8) and HCC/HCV (4.56±1.4) compared to the control group. Besides, serum CASC2 levels in the HCV group were significantly upregulated (14.9±3.6), while, downregulated in the HCC group (0.16± 0.03). Furthermore, The ROC analysis for diagnostic efficacy parameters indicated that CASC2 has higher accuracy (94.6%) and sensitivity (97.2%) for HCC diagnosis than AFP with an accuracy of (90.9%), sensitivity (69.4%), and MALAT1 showed an accuracy of (56.9%), sensitivity (72.2%).

Conclusion
Our study results indicated that CASC2 is a promising biomarker and is considered better and could help in HCC diagnosis on top of HCV than MALAT1 and the routine biomarker AFP.
Mindfulness meditation use in Britain during the COVID-19 pandemic
Authors: Simonsson Otto , Fisher Stephen D. 
Published: May 2024

Objectives
The objectives of this study were to examine the prevalence and associations of mindfulness meditation use and also its perceived mental health effects during the COVID-19 pandemic.

Methods
Using repeated cross-sectional data from broad online samples weighted to be representative of the adult population in Britain, we estimated the prevalence of mindfulness meditation use and employed logistic regression models to investigate sociodemographic and political associations of mindfulness meditation use and also its perceived mental health effects during the COVID-19 pandemic.

Results
The findings suggest that 16 percent of adults in Britain had learnt to practice mindfulness in 2021. In covariate-adjusted regression models, having learnt to practice mindfulness was more common among young and middle-aged adults, residents in London, and respondents who voted for the Liberal Democrats. Among mindfulness meditation users who reported having practiced mindfulness during the COVID-19 pandemic, 60 percent reported that it positively affected their mental health and 24 percent reported that it negatively affected their mental health. Notably, 41 percent of respondents with children under 18 (versus 13 percent of those without minors) reported negative mental health effects. In covariate-adjusted regression models, negative mental health effects from mindfulness practice during the COVID-19 pandemic were not concentrated in any particular groups, except for respondents with children under 18.

Conclusions
Mindfulness meditation has become widespread in Britain, but the results in this study suggest that mindfulness meditation use may be concentrated in certain sociodemographic and political groups. The results also suggest that practicing mindfulness during the COVID-19 pandemic had positive mental health effects for a majority of users, but approximately one-quarter of users reported negative mental health effects. It is therefore important for future research to continue monitoring the prevalence of mindfulness meditation use in society and to investigate under what circumstances, for whom, and in what ways mindfulness-based practices may have negative effects on mental health.
Effects of elastic band resistance training on the physical and mental health of elderly individuals: A mixed methods systematic review
Authors: Li Aiying , Sun Yan , Li Meng , Wang Dongyang , Ma Xiaofeng 
Published: May 2024

ObjectivesElastic band resistance training in elderly individuals can improve physical fitness and promote mental health in addition to other benefits. This systematic review aimed to review, summarize, and evaluate quantitative, qualitative, and mixed methodological studies on the use of elastic band resistance training in elderly individuals, and to investigate the influence of elastic band resistance training on the physical and mental health of elderly individuals, as well as their preferences and obstacles in training.MethodsA convergent separation approach was used to synthesize and integrate the results, specifically the mixed systematic review approach recommended by the Joanna Briggs Institute. The extensive search strategy included electronic database searches in the Cochrane Library, PubMed, Embase, Web of Science, Google Scholar, MEDLINE, and CINAHL. The researchers rigorously screened the literature, extracted and analyzed the data, and evaluated the quality of the included studies using the Mixed Methods Appraisal Tool (MMAT).ResultsTwenty-eight studies were included, of which 25 were quantitative studies, 2 were qualitative studies, and 1 was a mixed-methods study. A total of 1,697 subjects were investigated across all studies. Quantitative evidence supports the notion that elastic band resistance training can improve upper and lower limb flexibility, endurance, upper strength, physical balance, and cardiopulmonary function and enhance the mental health of elderly individuals. Participants in the qualitative study reported some preferences and obstacles with band resistance training, but most participants reported physical benefits.ConclusionsDespite the heterogeneity between studies, this review is the first systematic review to comprehensively evaluate the effectiveness of elastic band resistance training in older adults. It not only shows the influence of elastic band resistance training on the physical and mental health of the elderly, but also emphasizes the preference and obstacles of elderly individuals face.
Medical resource usage for COVID-19 evaluated using the National Database of Health Insurance Claims and Specific Health Checkups of Japan
Authors: Fukuyama Keita , Mori Yukiko , Ueshima Hiroaki , Ito Shiho , Tanabe Masaki , Kuroda Tomohiro 
Published: May 2024

Purpose
The coronavirus disease 2019 (COVID-19) pandemic exhibited several different waves threatening global health care. During this pandemic, medical resources were depleted. However, the kind of medical resources provided to each wave was not clarified. This study aimed to examine the characteristics of medical care provision at COVID-19 peaks in preparation for the next pandemic.

Methods
Using medical insurance claim records in Japan, we examined the presence or absence of COVID-19 infection and the use of medical resources for all patients monthly by age group.

Results
The wave around August 2021 with the Delta strain had the strongest impact on the working population in terms of hospital admission and respiratory support. For healthcare providers, this peak had the highest frequency of severely ill patients. In the subsequent wave, although the number of patients with COVID-19 remained high, they were predominantly older adults, with relatively fewer patients receiving intensive care.

Conclusions
In future pandemics, we should refer to the wave around August 2021 as a situation of medical resource shortage resulting from the COVID-19 pandemic.
Learner corpus research: a critical appraisal and roadmap for contributing (more) to SLA research agendas
Authors: Paquot Magali 
Published: May 2024

Abstract
Over the past decade, learner corpora have gained recognition as valuable data sources in Second Language Acquisition (SLA) research. This development can be attributed to significant progress in Learner Corpus Research (LCR). However, there is still substantial work to be done. This article highlights key issues essential for sustaining the relevance of learner corpora in SLA. More particularly, I focus on the need for more diverse types of learner corpora, stress the importance of detailed metadata, and advocate for multifactorial study designs. I then revisit ongoing debates regarding the role of the native speaker in LCR and propose a practical solution to address this thorny issue. Finally, I also readdress the need for improvement in the quantitative methods and statistics, arguing that the importance of robust quantitative analysis cannot be overstated. In conclusion, I envision an ambitious learner corpus compilation project that adheres to the FAIR principles, with the goal of further elevating study quality in LCR.
Logistics distribution route optimization of electric vehicles based on distributed intelligent system
Authors: Luan Rui 
Published: May 2024

Abstract
The data management system of health cloud authentication plays an important role in the optimization of logistics vehicle routing. It can not only help logistics vehicles choose the best distribution path, but also save time and cost and improve economic efficiency. At present, logistics has not yet formed a complete service system. High distribution costs and low distribution efficiency limit the development of the entire logistics. The reduction of logistics costs and the improvement of distribution efficiency have become the top priorities of the society. The optimization of the distribution route is the key to cost saving and distribution logistics. It is particularly important to study and optimize the distribution route, because the distribution route affects the logistics transportation efficiency and the loss cost during transportation. Therefore, this paper adjusted the scheduling system of logistics vehicles through a distributed intelligent system, and optimized the path of logistics vehicles according to the improved genetic algorithm, thereby reducing the transportation cost of logistics and improving the efficiency of logistics distribution. This article first explains the definition, classification, and main components of the delivery vehicle routing problem. Then, using cloud authentication path optimization, a distributed intelligent system is constructed. Finally, an improved ant colony algorithm is used to analyze and study the distance constraints of vehicles. By improving the ant colony algorithm, it can be seen that the optimized path pheromone concentration and the optimized sub-function have gradually increased with time. The mean pheromone concentration was 40 %, and the seventh day was 15 % higher than the first. The mean value of the optimized subfunction was 0.34 %, and the seventh day was 20 % higher than the first. The distribution cost and distribution efficiency of the optimized logistics vehicle distribution path were much higher than those of the traditional logistics distribution path. Moreover, the distribution cost of the logistics distribution path was 9 % lower than the traditional one, and the distribution efficiency was 13 % higher. The average smoothness of the optimized logistics path is about 90 %, and the seventh day is 11 % higher than the first day. The average fitness of the optimized logistics path is 88 %, and the seventh day is 14 % higher than the first day. In a word, the data management system can uniformly schedule logistics vehicles and improve the efficiency of distribution.
Shifts in digital media usage before and after the pandemic by Rusyns in Ukraine
Authors: Wood Jack 
Published: May 2024

Abstract
The COVID-19 pandemic touched every corner of the globe, even impacting the sphere of linguistics in terms of communication, lexis, and how linguists conduct their research. However, Rusyn, a minority language in Ukraine’s Transcarpathian region, took advantage of this period in a new attempt at revitalization. Rusyn is spoken in several European countries and has the privilege of being recognized and protected in most of them. Ukraine does not, however, consider Rusyn to be a language, and, therefore, does not protect it. There have been several movements for recognition and autonomy in the past, but all have been unsuccessful. The pandemic gave this small community of speakers a new chance to elevate their work towards boosting the language’s vitality and status through digital platforms such as YouTube and collective writing projects. This paper looks at the before-and-after of the pandemic in relation to Rusyn in Transcarpathia, focusing on the shift in digital approaches to protecting and promoting the language. It concludes that, in fact, a shift has occurred in terms of utilizing digital media in order to promote the language.
Spione, Agentinnen, Vertrauensleute
Authors: Fügen Maximilian , Pöhlmann Markus 
Published: May 2024

Zusammenfassung
Spionage steht bis heute in der öffentlichen wie auch in der geschichtswissenschaftlichen Wahrnehmung oftmals gleichbedeutend für den militärischen Nachrichtendienst. Dabei macht sich dieses verkürzte Verständnis an dramatischen und prominenten Einzelfällen fest. Der Aufsatz zielt darauf ab, Spionage als militärische Aufgabe für die Gründungsphase der militärischen Nachrichtendienste durch eine empirische Untersuchung der Akteursgruppe besser zu verstehen. Dazu erschließen die Autoren erstmals die Zahl, das soziale Herkommen und die besonderen Einsatzarten der Agentinnen und Agenten im Dienst des preußisch-deutschen Heeres während des Ersten Weltkrieges.
Primary omental infarction – a benign cause of acute abdomen
Authors: Pemmada Vikas , Shetty Athish , Koteshwar Prakashini , Rajpurohit Siddesh , Bhat Ganesh 
Published: May 2024

Abstract

Objectives
Omental infarction (OI) is an uncommon cause of acute abdominal pain. A high index of clinical suspicion is required for diagnosis of OI as the incidence is less than 1 %, presenting with abdominal pain. We report primary OI’s clinical and radiological profile from a single tertiary care hospital in India.

Methods
In this retrospective cross-sectional study, the electronic medical and radiology records of patients with abdominal pain were reviewed over seven years (2015–2022). Variables were systematically collected and analyzed.

Results
A total of 22 patients diagnosed with primary OI were included in this study. Male preponderance (63.6 %) was noted with a mean age of 47.45 years (SD ± 13.84; range: 18–72 years). Most patients belonged to class I obesity (according to the Asia-Pacific body mass index classification) with a mean BMI of 26.56 kg/m2 (SD ± 3.21 kg/m2). All patients had abdominal pain as the primary symptom, with a mean duration of 8.64 days (SD ± 10.15; range: 1–42 days). The most common locations of pain were the right hypochondrium (27.3 %) and diffuse (27.3 %), followed by the right iliac fossa (18.1 %). Most (95.45 %, n=21/22) patients were treated conservatively, and only one required surgical intervention.

Conclusions
Primary OI is a rare and benign cause of acute abdomen. Obesity is a risk factor but does not correlate with the size or severity of OI. Radiological imaging, like a computed tomography (CT) scan, is essential for diagnosis. A conservative management line should be the first approach in treating primary OI before considering surgical options.
Effect of basalt fiber length on the behavior of natural hydraulic lime-based mortars
Authors: Cobo Escamilla Alfonso , Bautiste Villanueva Purificación , Prieto Barrio María Isabel , González García María de las Nieves , Vázquez Bouzón Analía 
Published: May 2024

Abstract
The number of studies aimed at the characterization of reinforced lime-based mortars for use in the rehabilitation of historic buildings is still very small. This fact contrasts with the growing interest of the industry in these products as substitutes for cement mortars, both for their constructive advantages (compatibility requirements) and their lower cost (economic and environmental). For this reason, this study investigates the effect of basalt fiber length on the physical, mechanical, and durability properties of reinforced natural hydraulic lime mortars and provides criteria for selecting optical blends to meet the various performance requirements for their use as building materials for traditional and contemporary structures. Specimens with 1% volume of basalt fibers and lengths of 6, 12, 18, and 24 mm have been tested. The results in fresh mortar show that increasing the fiber length decreases the consistency and bulk density, as well as increases the air content. Regarding the durability properties of hardened mortar, no direct relationship is observed between fiber length and the decrease in the water absorption coefficient of reinforced mortars. Nor is there a clear relationship between fiber length and the increase in Shore hardness and the decrease in adhesive strength in the reinforced mortars. On the contrary, for small lengths (up to 12 mm), there is a direct relationship between fiber length and the increase in other fundamental mechanical properties such as flexural and compressive strength. Based on the results obtained, a predictive model is proposed to determine the amplification factor of flexural and compressive strength as a function of fiber length.
Toxicity parameters of a new 1,2,4-triazole derivative when subcutaneously injected to guinea pigs
Authors: Zazharskyi V. V. , Bigdan O. A. , Parchenko V. V. , Karpenko Y. V. , Zazharska N. M. , Mykhailiuk Y. O. , Kulishenko O. M. , Davydenko P. O. , Kulish S. M. , Gutyj B. V. 
Published: May 2024

The results of the literature analysis indicate a wide spectrum of biological activity of 1,2,4-triazole derivatives. Low toxicity, reactivity, and high biological activity of 1,2,4-triazole derivatives make this class of compounds very attractive. The obtained data determine the relevance of further studies of 1,2,4-triazole derivatives to find new highly effective biologically active substances that can become the basis for new medicines. Our further work aimed to study some toxicity parameters of 3-(3-fluorophenyl)-6-(4-methoxyphenyl)-7H-[1,2,4]-triazolo-[3,4-b][1,3,4] thiadiazine when administered subcutaneously to guinea pigs, which is a necessary condition for further implementation in practice of this compound. In this work, we observed an absence of toxic effects after a single subcutaneous injection to guinea pigs at a dose of 40 mg/kg experimental drug. The results of macro- and microscopic examinations of internal organs 14 days after a single subcutaneous injection of the studied compound at a dose of 20, 40 mg/kg showed the absence of any anatomical and morphological disorders in the tissue structures of guinea pigs. The calculated value indicates a high degree of safety of 3-(3-fluorophenyl)-6-(4-methoxyphenyl)-7H-[1,2,4]-triazolo-[3,4-b][1,3,4] thiadiazine and its prospects for use in veterinary practice as an effective and safe tuberculocidal agent.
ВИКОРИСТАННЯ РЕГЕНЕРОВАНИХ ВІДХОДІВ ВИРОБНИЦТВА СОНЯШНИКОВОЇ ОЛІЇ У СКЛАДІ ЕЛАСТОМЕРНИХ КОМПОЗИЦІЙ ДЛЯ ВИГОТОВЛЕННЯ ЕЛЕМЕНТІВ ШИН
Authors: Соколова Ліна О. , Суха Ірина В. , Панфілова Олександра А. , Овчаров Валерій І. , Тищенко Валерія О. 
Published: May 2024

Одним з проєктів екологічної економіки України є використання відходів виробництва соняшникової олії у складі гумових сумішей, що дозволяє поліпшити властивості композиційних еластомерних матеріалів та знизити негативний вплив на навколишнє середовище. Завдяки унікальному складу відпрацьованих фільтрувальних матеріалів стадії вінтеризації виробництва соняшникової олії, отримані після регенерації продукти можуть знайти широке застосування у якості поліфункціональних інгредієнтів еластомерних композицій. Досліджувана жиро-, восковмісна фракція, використана у складі гум для виготовлення елементів шин, дозволила до 20 % підвищити адгезійні властивості гумових сумішей (клейкість та когезійну міцність), на чверть зберегти пружньо-міцносні властивості гум після теплового старіння та покращити на 30 % їх динамічні властивості.