bluuebunny/crossref_metadata_2025_split huggingface dataset:
Both Knee Re-revision Operations with Different Types of Endoprosthesis after Septic Complications
Authors: Zebolds Silvestris , Goncars Valdis , Zommers Ints , Kalnberzs Konstantins 
Published: July 2012

Both Knee Re-revision Operations with Different Types of Endoprosthesis after Septic Complications
We report about the patient who underwent seven replacement operations in both knees during twelve years period. Different types of implants were used due to clinical situation and septic complications.
Torsion of the Diverticulum of the Appendix
Authors: Engelis Arnis , Zviedre Astra , Pilmane Mara , Petersons Aigars 
Published: July 2012

Torsion of the Diverticulum of the AppendixWe report a case of a 1-year-old girl, operated on due to the symptoms of acute appendicitis. Torsion, necrosis and perforation of the large diverticulum of theappendix vermiformis, causing peritonitis were found during the operation. The complete luminary connection between appendix and the diverticulum was proved. Although appendix vermiformis itself was not the reason for the peritonitis, it was removed together with the diverticulum. The child's recovery after the operation was stable. The morphology revealed that the diverticulum ofappendix vermiformisgenerally possessed features typical of a large intestine columnar epithelium, while its other layers, including a muscular layer and an irregularly expanded sub-mucosal layer, remained similar to the wall of the appendix. We suggest that the torsion of the true congenital diverticulum of the vermiform appendix mimicked acute appendicitis and caused peritonitis in the above-mentioned girl.
Effect of Peak-Aged Heat Treatment on Corrosion Behavior of the AA6063 Alloy Containing Al3Ti
Authors: Cevik E. , Sun Y. , Ahlatci H. 
Published: July 2012

Effect of Peak-Aged Heat Treatment on Corrosion Behavior of the AA6063 Alloy Containing Al3TiThe purpose of this study is to analyse the microstructure and corrosion properties of homogenised and aged AA 6063 aluminium alloys, containing up to 2% Ti, after the conventional casting technique. The microstructure of the homogenised and aged alloys was examined using an optic microscope, and scanning electron microscope. The micro-hardness test was used for the hardness measurements of the investigated alloys. Corrosion tests were performed by suspending samples of certain sizes into 30 gr/l NaCl + 10 ml/l HCl solutions, measuring the mass loss; potentiodynamic polarisation measurements were carried out in the same solution. The microstructure characterization of the investigated alloys shows the Al (matrix), non-shaped dark globular grey-coloured phase and rod-shaped phases formed at the grain boundaries. The non-shaped dark grey-coloured phase is Mg2Si. The rod-shaped phase, formed in the microstructure of the Ti-added AA 6063 alloys, is Al3Ti. The Ti content of the alloy increases, the Al3Ti phase tends to elongate and become plated. The results of the corrosion tests proved that the corrosion rate decreased in alloys containing less than 1% Ti, and the rate of corrosion increased in alloys containing more than 1% Ti, regardless of whether the alloys were homogenised and aged. Another observation was that aging heat treatment improved corrosion resistance.
Electrocatalytically Active Ni - Re Binary Alloys Electrodeposited with Superimposed Magnetic Field
Authors: Żabiński P. , Franczak A. , Kowalik R. 
Published: July 2012

Electrocatalytically Active Ni - Re Binary Alloys Electrodeposited with Superimposed Magnetic FieldThe aim of this work was to obtain Ni-Re binary alloy by a simple method of electrodeposition. Nickel - rhenium alloys have been deposited from nickel sulfamate and ammonium perrhenate electrolyte with citrate-anion additives. The effect of magnetic field superimposed during electrodeposition was studied. The impacts of that parameter on hydrogen evolution process for obtained Ni-Re alloys were examined. The deposited layers were determined by optical and scanning electron microscopy (SEM), X-ray diffraction (XRD) and X-ray fluorescence (XRF).
Depth-Profiles of Corrosion Properties of Carbonitrided AISI 405 Steel
Authors: Jagielska-Wiaderek K. 
Published: July 2012

Depth-Profiles of Corrosion Properties of Carbonitrided AISI 405 SteelElectrochemical polarisation characteristics of AISI 405 type stainless steel, carbonitrided in fluid flow, are presented. The evaluation of the corrosion resistance of carbonitrided stainless steel was carried out by using the so called progressive thinning method, consisting in determination of polarisation characteristics on increasingly-deeper situated regions of the top layer. This method made it possible to determine changes in particular corrosion parameters read out from potentiokinetic polarisation curves, thus enabling the depth profiles of these parameters. The resistance of the AISI 405 steel against acid corrosion was determined in acidified 0.5M sulphate solutions having three different pH values, namely 1, 2 and 4. The thickness of the carbonitrided layer has been evaluated on the basis of the spectrophotometric analysis of carbon content and microhardness on the cross section of the surfacial layer.
Twenty-Four–hour Duration of Effect of Intranasal Corticosteroids for Seasonal Allergic Rhinitis Symptoms: Clinical Evidence and Relevance
Authors: DuBuske Lawrence M. 
Published: July 2012

Background Seasonal allergic rhinitis (SAR) symptoms are often most severe and/or disruptive during overnight and morning hours, resulting in cognitive/performance impairments and reduced quality of life throughout the following day. Surveys of allergy patients and health care practitioners reveal a common perception that intranasal steroids (INSs), many of which are dosed q.d., fail to adequately relieve symptoms for a full 24 hours. This review assessed whether perceptions of the 24-hour duration of action of INSs correspond with duration of action documented in clinical literature. Methods SAR clinical trial literature of the last 5 years was reviewed to identify studies of INSs incorporating morning instantaneous (A.M. NOW) or instantaneous assessments of 24-hour duration of action. Results In numerous placebo-controlled trials of INSs in patients with SAR, treatment was associated with significantly greater improvements in A.M. NOW symptoms from baseline versus placebo. For congestion, this is noteworthy, because patients often cite this symptom, especially in the morning, as the most bothersome symptom. Comparison of A.M. NOW and daily scores suggests minimal drop in efficacy at 24 hours postdose. In several studies, INS treatment was found superior to intranasal or oral antihistamines in A.M. NOW symptom improvement. Conclusion Once-daily INSs have potential for effective 24-hour symptom relief; however, there is an apparent disconnect between these findings and patient/physician perceptions. This discrepancy may be explained, in part, by less-than-ideal treatment adherence among “real-world” patients versus subjects treated in clinical trials. Proactive counseling can encourage proper INS use and help maximize treatment benefits.
Increased Expression of Intelectin-1 in Nasal Polyps
Authors: Park Il-Ho , Park Se-Jin , Cho Jung-Sun , Moon You-Mi , Kim Tae Hoon , Lee Sang Hag , Lee Heung-Man 
Published: July 2012

Background Intelectin-1 is a new type of Ca2+-dependant soluble lectin in humans that has affinity for galactofuranose in carbohydrate chains of bacterial cell walls, indicating that intelectin-1 may play a role in immune defense against bacteria. The purpose of the current study was to determine the expression of intelectin-1 mRNA and protein and to localize intelectin-1 protein in nasal polyps and tissues from control subjects. Methods Normal sphenoid sinus mucosa was obtained from 10 patients undergoing surgery for pituitary tumor. Nasal polyp samples were obtained from 10 patients undergoing endoscopic sinus surgery for chronic polypoid rhinosinusitis. Real-time polymerase chain reaction (PCR) was performed for intelectin-1 mRNA. Immunofluorescent staining was done for localization of intelectin-1 and quantitatively analyzed using computer-based image analysis. Western blot analysis was performed. Results Real-time PCR and Western blot analysis showed that intelectin-1 expression in nasal polyps was increased compared with normal sinus mucosa. Using immunofluorescent staining, intelectin-1 was strongly stained in epithelium and submucosa of nasal polyps, and faint staining was found in normal sinus mucosa. Conclusions Intelectin-1 is expressed in human sinus mucosa and is increased in patients with nasal polyps. These results suggest a possible contribution for intelectin-1 in the pathophysiology of nasal polyps.
Efficacy of Chinese Herbal Medicine Compared with a Macrolide in the Treatment of Chronic Rhinosinusitis without Nasal Polyps
Authors: Jiang Rong-San , Wu Shang-Heng , Tsai Chen-Chen , Li Ya-Hsin , Liang Kai-Li 
Published: July 2012

Background This study was designed to examine the efficacy of Chinese herbal medicine (CHM) in the treatment of chronic rhinosinusitis (CRS) without nasal polyps. Methods Patients with CRS without nasal polyps were enrolled in the study. Before treatment, they were evaluated by the Taiwanese version of the 20-item Sino-Nasal Outcome Test (TWSNOT-20), nasal endoscopy, saccharin test, and bacterial culture. Then, they were randomized to take CHM (Tsang-Erh-San extract granules and Houttuynia extract powder) or erythromycin for 8 weeks. After treatment, they were evaluated again by the TWSNOT-20, nasal endoscopy, saccharin test, and bacterial culture. Results Fifty-three patients completed the study with 26 in the CHM group and 27 in the erythromycin group. In both the CHM and the erythromycin groups, TWSNOT-20 scores significantly decreased after treatment, but the decrease was not significantly different between the two groups. However, the saccharin transit times were shortened in more patients in the CHM group than in patients in the erythromycin group. Conclusion Our results showed CHM had an efficacy similar to that of macrolides in the treatment of CRS without nasal polyps. However, a placebo effect remained possible in both treatment groups.
Intramucosal Bacterial Microcolonies Exist in Chronic Rhinosinusitis without Inducing a Local Immune Response
Authors: Wood Andrew J. , Fraser John D. , Swift Simon , Patterson-Emanuelson Emma A.C. , Amirapu Satya , Douglas Richard G. 
Published: July 2012

Background Although chronic rhinosinusitis (CRS) causes very significant morbidity, much about its pathogenesis remains uncertain. Recent studies have identified polymicrobial biofilms on the surface of sinus mucosa and Staphylococcus aureus within the sinus mucosa of patients with CRS, both with and without nasal polyps. The pathogenic implications of intramucosal bacteria in CRS are unknown. This study was designed to determine the prevalence and species of bacterial colonies within the sinus mucosa of adult patients with and without CRS and to describe the relationship of these bacterial colonies to the host immune response. Methods Sinus mucosa from patients with and without CRS was examined using Gram and Giemsa staining, immunohistochemistry, bacterial culture, and fluorescence in situ hybridization techniques. Results Bacterial microcolonies were observed within the mucosa in 14 of 18 patients with CRS. In 10 of these patients colonies were positively identified as S. aureus. Staphylococcal microcolonies were observed at a lower level (1 of 8 patients) in normal sinus mucosa. There was no correlation between detection of S. aureus on the mucosal surface and microcolonization of the mucosa. Surprisingly, there was no evidence of an immune reaction to microcolonies. Indeed, fewer T lymphocytes (p = 0.03) and eosinophils (p = 0.03) were counted immediately surrounding the microcolonies compared with uninfected areas of the same tissue. Conclusion Bacterial microcolonies are prevalent within paranasal sinus mucosa and are commonly S. aureus. These microcolonies do not provoke immune detection and may represent a phenotype that actively evades host immunity. This may underpin the rcalcitrance of CRS to antibiotic therapy. These findings challenge classic views of both infection and mucosal immunity in human chronic disease. The presence of intramucosal bacteria in samples of normal sinus mucosa also questions the sensitivity of detecting nasal carriage of pathogens by swabbing the surface of the anterior nares.
Nitrogen Response Behaviour of Developed Promising Lines of T.Aman Rice
Authors: Saha PK , Islam SMM , Akter M , Zaman SK 
Published: July 2012

Nitrogen is the most limiting nutrient for rice. Modern high yielding rice varieties may have differences in accumulating and using N from soil and applied fertilizer. A field experiment with 8 rice genotypes was conducted during 2008 wet season (T.Aman season) to study the effect of different rates of N fertilization on the yield performance and nitrogen nutrition under irrigated condition. Among the tested varieties/lines, BR7155-20-1-3 produced the significantly highest grain yield of 5.04 t/ha at N30 level followed by Swarna (4.66 t/ha) at the same level of N with similar growth duration (140 days). Agronomic efficiency of added N ranged from 0.7 to 23.3 for the promising line BR7155-20-1-3 and 3.3 to 27.0 for variety Swarna. Grain yield at No was the highest in BR7155-20-1-3 followed by the variety Swarna and the lowest in BR7870-5 *(Nils)- I 0-HR8. Percent nitrogen recovery ranged from 50 to 63 for variety Swarna and 13 to 30 for promising line BR7155-20-1-3. The promising line BR7155 20-1-3 and the variety Swarna may be economically advantageous over the other varieties/ lines. DOI: http://dx.doi.org/10.3329/bjar.v37i2.11222 Bangladesh J. Agril. Res. 37(2): 207-213, June 2012
Effect of BAU-Biofungicide, Neem Oil and a Nematicide on the Root-Knot (Meloidogyne javanica) of Papaya (Carica papaya)
Authors: Pradhan MAA , Rahaman MM , Paul SK , Ahamad MU , Goswami BK 
Published: July 2012

In a pot experiment, BAU-Biofungicide (Trichoderma harzianum) neem oil and curaterr (carbofuran) 5G were tested against root-knot (Meloidogyne javanica) of two papaya varieties Kashempuri and Deshi papaya. Seedlings were inoculated with second stage larvae of M. javanica. Neem oil (5 ml/ 10g seeds) and BAU-Biofungicide (1:4) were used as seed treatant and curaterr as side dressing. Both the bio-agents significantly increased the root and shoot growth of papaya plant and reduction of galls and eggmasses and suppressed the development of J2, J3, and J4 and adult females of M. javanica. Efficacy of BAU-Biofungicide was to reduce the gall and nematode development and to increase plant growth was similar to nematicide curaterr. BAU-Biofungicide gave higher effect in most of the growth characters compared to neem oil and prevented the development of adult females and juveniles like nematicide curaterr. DOI: http://dx.doi.org/10.3329/bjar.v37i2.11230 Bangladesh J. Agril. Res. 37(2): 271-277, June 2012
CHARACTERIZATION OF BACTERIA ASSOCIATED WITH PNEUMONIA IN BLACK BENGAL GOATS
Authors: Momin MA , Islam MA , Khatun MM , Rahman MM , Islam MA 
Published: July 2012

The present research work was undertaken for the characterization of the bacterial pathogens responsible for pneumonia in black Bengal goats. Nasal swab samples (n = 50) were collected from the pneumonic black Bengal goats in Mymensingh and Sirajgonj districts. Samples were inoculated onto nutrient agar, eosin methylene blue (EMB) agar, MacConkey agar, and blood agar media for isolation of bacteria. Identification of bacteria was performed by the Gram's staining method, cultural properties and biochemical tests. Antibiotic sensitivity of bacterial isolates was performed against 11 antimicrobial agents. Pasteurella spp were isolated from 25 cases, and Staphylococcus spp from 13 cases. Mixed infection caused by the Pasteurella spp and Staphylococcus spp. were recorded in 12 cases. Pasteurella spp produced whitish, opaque circular and translucent colonies on nutrient agar, smooth, convex, glistening colonies on EMB agar and no hemolysis on blood agar. Staphylococcus spp have shown gray white or golden yellowish colonies on nutrient agar. Golden yellow colonies without hemolysis or whitish colonies with hemolysis were also produced by Staphylococcus spp. on the blood agar media. Pasteurella spp were indole positive, MR-VP negative and ferment dextrose, sucrose and mannitol with the production of acid. The Staphylococcus spp were positive to MR-VP, coagulase and catalase reactions, negative to indole test and fermented five basic sugars with acid production. Results of cultural and biochemical tests supported that these two isolates belonged to P. multocida and S. aureus. P. multocida were highly sensitive to ciprofloxacin and resistant to penicillin. S. aureus found to be highly sensitive to erythromycin, tetracycline, enrofloxacin, and norfloxacin and less sensitive to amoxicillin. DOI = http://dx.doi.org/10.3329/bjvm.v9i1.11215Bangl. J. Vet. Med. (2011). 9(1): 67-71
Anterior Chest Wall Involvement in Early Stages of Spondyloarthritis: Advanced Diagnostic Tools
Authors: RAMONDA ROBERTA , LORENZIN MARIAGRAZIA , LO NIGRO ALESSANDRO , VIO STEFANIA , ZUCCHETTA PIETRO , FRALLONARDO PAOLA , CAMPANA CARLA , OLIVIERO FRANCESCA , MODESTI VALENTINA , PUNZI LEONARDO 
Published: July 2012

Objective.Anterior chest wall (ACW) involvement is difficult to evaluate in patients with spondyloarthritis (SpA). Bone scan is sensitive to ACW involvement, while magnetic resonance imaging (MRI) detects early alterations in SpA. We compared the sensitivity and specificity of bone scans and MRI in assessing ACW in early SpA.Methods.Out of 110 patients with early SpA attending the Outpatient Rheumatology Unit Clinic of Padua University from January 2008 to December 2010, the 40 complaining of pain and/or tenderness [60% with psoriatic arthritis (PsA), 12.5% with ankylosing spondylitis, and 27.5% with undifferentiated SpA] underwent bone scans and MRI.Results.At clinical examination, sternocostoclavicular joints were involved in 87.5% on the right, 77.5% on the left, and 35% on the sternum. Bone scan was positive in 100% and MRI in 62.5% of these patients. Early MRI signs (bone edema, synovial hyperemia) were observed in 27.5%, swelling in 5%, capsular structure thickness in 37.5%, erosions in 15%, bone irregularities in 15%, osteoproductive processes in 12.5%, and osteophytes in 5%. A higher prevalence of Cw6, Cw7, B35, and B38 was found in 15%, 48%, 28%, and 12%, respectively, of the patients with PsA who had bone scans.Conclusion.Noted mainly in women, ACW involvement was frequent in early SpA. Both bone scans and MRI are useful in investigating ACW inflammation. Bone scans were found to have high sensitivity in revealing subclinical involvement, but a low specificity. MRI provides useful information for therapeutic decision making because it reveals the type and extent of the process. The significant associations of HLA-Cw6 and Cw7 with PsA could suggest that genetic factors influence ACW involvement.
Donor NK Cells and IL-15 Promoted Engraftment in Nonmyeloablative Allogeneic Bone Marrow Transplantation
Authors: Hu Bo , Bao Guangming , Zhang Yinsheng , Lin Dandan , Wu Yan , Wu Depei , Liu Haiyan 
Published: July 2012

Abstract
Donor NK cells could promote engraftment by suppressing host alloreactive responses during allogeneic bone marrow transplantation (allo-BMT). The biological activity of NK cells could be significantly enhanced by IL-15. The current study attempted to evaluate the effect of donor NK cells and IL-15 administration on engraftment and immune reconstitution in a murine nonmyeloablative allo-BMT model. Mice infused with donor NK cells and treated with IL-15 during nonmyeloablative allo-BMT resulted in increased donor engraftment compared with either treatment alone. The number of donor-derived cell subsets also increased in the spleen of the recipient mice with combination treatment. The alloreactivity to donor type Ags was significantly reduced in the recipient mice with donor NK cell infusion and IL-15 treatment, which was manifested by decreased proliferation and IL-2 secretion of splenocytes from recipient mice in response to donor type Ags in MLR and decreased capacity of the splenocytes killing donor type tumor targets. We subsequently exposed recipient mice to reduced irradiation conditioning and showed that donor NK cell infusion and hydrodynamic injection-mediated IL-15 expression could synergistically promote donor engraftment and suppress alloreactivity during nonmyeloablative allo-BMT. Infusion of CFSE-labeled donor CD45.1+ NK cells demonstrated that IL-15 could enhance the infused donor NK cell proliferation and function in vivo. IL-15 treatment also promoted donor bone marrow-derived NK cell development and function. Thus, donor NK cell infusion and IL-15 treatment could synergistically promote the engraftment and the development of donor-derived cell subsets and suppress the host alloresponse in a murine nonmyeloablative allo-BMT model.
A Coreceptor-Independent Transgenic Human TCR Mediates Anti-Tumor and Anti-Self Immunity in Mice
Authors: Mehrotra Shikhar , Al-Khami Amir A. , Klarquist Jared , Husain Shahid , Naga Osama , Eby Jonathan M. , Murali Anuradha K. , Lyons Gretchen E. , Li Mingli , Spivey Natali D. , Norell Håkan , Martins da Palma Telma , Onicescu Georgiana , Diaz-Montero C. Marcela , Garrett-Mayer Elizabeth , Cole David J. , Le Poole I. Caroline , Nishimura Michael I. 
Published: July 2012

Abstract
Recent advancements in T cell immunotherapy suggest that T cells engineered with high-affinity TCR can offer better tumor regression. However, whether a high-affinity TCR alone is sufficient to control tumor growth, or the T cell subset bearing the TCR is also important remains unclear. Using the human tyrosinase epitope-reactive, CD8-independent, high-affinity TCR isolated from MHC class I-restricted CD4+ T cells obtained from tumor-infiltrating lymphocytes (TIL) of a metastatic melanoma patient, we developed a novel TCR transgenic mouse with a C57BL/6 background. This HLA-A2–restricted TCR was positively selected on both CD4+ and CD8+ single-positive cells. However, when the TCR transgenic mouse was developed with a HLA-A2 background, the transgenic TCR was primarily expressed by CD3+CD4−CD8− double-negative T cells. TIL 1383I TCR transgenic CD4+, CD8+, and CD4−CD8− T cells were functional and retained the ability to control tumor growth without the need for vaccination or cytokine support in vivo. Furthermore, the HLA-A2+/human tyrosinase TCR double-transgenic mice developed spontaneous hair depigmentation and had visual defects that progressed with age. Our data show that the expression of the high-affinity TIL 1383I TCR alone in CD3+ T cells is sufficient to control the growth of murine and human melanoma, and the presence or absence of CD4 and CD8 coreceptors had little effect on its functional capacity.