bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thalamic single‐unit and local field potential activity in Tourette syndrome
Authors: Marceglia Sara , Servello Domenico , Foffani Guglielmo , Porta Mauro , Sassi Marco , Mrakic‐Sposta Simona , Rosa Manuela , Barbieri Sergio , Priori Alberto 
Published: January 2010

AbstractDeep brain stimulation (DBS) of the ventralis oralis (VO) complex of the thalamus improves tics in patients with Tourette syndrome (TS). To neurophysiologically describe the VO complex we recorded, in seven patients with TS undergoing DBS electrode implantation, single‐unit activity during surgery and local field potentials (LFPs) a few days after surgery. Single unit recordings showed that the VO complex is characterized by a localized pattern of bursting neuronal activity. LFP spectra demonstrated that VO of TS patients has a prominent oscillatory activity at low frequencies (2–7 Hz) and in the α‐band (8–13 Hz), and a virtually absent beta activity. In each patient, the main LFP frequency significantly correlated with single‐unit interburst frequency. In conclusion, we observed an oscillatory bursting activity in the VO as target region in patients with severe TS undergoing DBS surgery. © 2010 Movement Disorder Society
Psychiatric disorders in adult‐onset focal dystonia: A case‐control study
Authors: Fabbrini Giovanni , Berardelli Isabella , Moretti Germana , Pasquini Massimo , Bloise Maria , Colosimo Carlo , Biondi Massimo , Berardelli Alfredo 
Published: January 2010

AbstractIn a single‐center, case–control study, we investigated the frequency and types of psychiatric disturbances in 89 consecutive patients with various primary focal dystonias (34 had cervical dystonia (CD), 28 blepharospasm (BPS), 16 laryngeal dystonia (LD), and 11 arm dystonia), 62 healthy control subjects and as controls for BPS, 26 patients with hemifacial spasm (HFS). Patients and controls underwent a full psychiatric evaluation. Diagnosis was based on the structured clinical interview for DSM‐IV, obsessive‐compulsive disorder (OCD) was assessed with the Yale‐Brown Obsessive‐Compulsive scale, anxiety with the Hamilton Rating Scale for Anxiety, the severity of depression with the Beck Depression Inventory. Of the 89 patients with focal dystonias studied, 51 patients (57.3%) had a diagnosis of psychiatric disorders compared with only 15 of 62 healthy subjects (24.1%) and 9 of the patients with HFS (34.6%). Depressive disorders were more frequent in the CD and BPS groups than in healthy controls, whereas the frequency of anxiety disorders, OCDs or adjustment disorders approached that of healthy subjects. No difference was found in the frequency of any specific psychiatric disorder in patients with LD and arm dystonia and healthy controls. In 35 of 51 patients who had psychiatric disorders, these started before and in 16 patients after the onset of dystonia. No differences were found in age, dystonia severity, and duration of botulinum toxin treatment between patients with and without psychiatric disturbances. The most common psychiatric features in patients with CD and BPS are depressive disorders. © 2010 Movement Disorder Society
Utility of the WHO‐five well‐being index as a screening tool for depression in Parkinson's disease
Authors: Schneider Christine B. , Pilhatsch Maximilian , Rifati Martina , Jost Wolfgang H. , Wodarz Franziska , Ebersbach Georg , Djundja Daniela , Fuchs Gerd , Gies Arne , Odin Per , Reifschneider Gerd , Wolz Martin , Bottesi Antonia , Bauer Michael , Reichmann Heinz , Storch Alexander 
Published: January 2010

AbstractBeck depression inventory (BDI‐1A) is the gold standard screening tool for Parkinson's disease (PD) depression, but as a result of its complexity, it is of limited suitability as a quick and easy screening device. We, therefore, validate the 5‐item WHO‐Five Well‐being Index (WHO‐5) as a screening tool for PD depression. Two hundred thirteen of 215 recruited PD patients (99.1%) completed the WHO‐5. Receiver operating characteristic plots were used to calculate sensitivity/specificity for all cut‐off scores for the detection of depression and combined depression/dysthymia as assessed by an independent investigator using the Mini International Neuropsychiatric Interview (MINI). Internal consistency of the WHO‐5 was good (Cronbach's α = 0.83). WHO‐5 showed high validity with adequate detection of depression without differences in the validity indices compared to BDI‐1A (P = 0.234). The optimal cut‐off value for detection of depression was 12 of 13 points. WHO‐5 is a useful, brief, and easy instrument for identifying PD subjects with depression in daily practice. © 2010 Movement Disorder Society
Fragmentation arising from a distributional initial condition
Authors: Lamb W. , McBride A. C. , McGuinness G. C. 
Published: January 2010

AbstractA standard model for pure fragmentation is subjected to an initial condition of Dirac‐delta type. Results for a corresponding abstract Cauchy problem are derived via the theory of equicontinuous semigroups of operators on locally convex spaces. An explicit solution is obtained for the case of a power‐law kernel. Rigorous justification is thereby provided for results obtained more formally by Ziff and McGrady. Copyright © 2010 John Wiley & Sons, Ltd.
Global H3K9 dimethylation status is not affected by transcription, translation, or DNA replication in porcine zygotes
Authors: Park Ki‐Eun , Johnson Christine M. , Magnani Luca , Wang Xin , Biancardi Monica N. , Cabot Ryan A. 
Published: January 2010

AbstractMethylation of the lysine 9 residue of histone H3 (H3K9) is linked to transcriptional repression. The observed structure of chromatin in porcine and murine embryos is different with regard to H3K9 dimethylation status, leading to our hypothesis that the intracellular mechanisms responsible for H3K9 methylation would also differ between these two species. The objectives of this study were: (1) to determine the extent that DNA, mRNA, and protein synthesis serve in maintaining the asymmetrical distribution of dimethylated H3K9 in porcine zygotes, (2) determine the extent to which the intracellular localization of individual pronuclei correlated with H3K9 dimethylation status, and (3) to determine the abundance of transcripts encoding the histone methyltransferases, with H3K9 methylation activity, in porcine oocytes and embryos. Our findings are that (1) H3K9 dimethylation status is not affected by DNA replication, transcription, or protein synthesis, (2) the location of a pronucleus does not significantly affect the H3K9 dimethylation status of the chromatin within that pronucleus, and (3) the histone methyltransferases with activity for H3K9 differ in transcript abundance in porcine oocytes and cleavage stage embyros. These results support our hypothesis that there is a difference in intracellular mechanisms affecting dimethylation status of H3K9 between porcine and murine embryos. Mol. Reprod. Dev. 77: 420–429, 2010. © 2010 Wiley‐Liss, Inc.
A rare case of GATA1 negative chemoresistant acute megakaryocytic leukemia in an 8‐month‐old infant with trisomy 21
Authors: Stepensky Polina , Brooks Rebecca , Waldman Elisha , Revel‐Vilk Shoshana , Izraeli Shai , Resnick Igor , Weintraub Michael 
Published: January 2010

AbstractChildren with Down syndrome (DS) have a unique form of acute megakaryocytic leukemia (AMKL) characterized by the presence of mutations in the GATA1 gene leading to increased chemosensitivity and a favorable outcome. We describe an 8‐month‐old male with DS who was diagnosed with AMKL without a mutation in the GATA1 gene. The patient was treated according to the DS‐AML‐regimen but his disease progressed and he succumbed 9 months later. This rare case of DS AMKL without a GATA1 mutation with an unfavorable outcome suggests that GATA1 testing may play a useful role in initial stratification. Pediatr Blood Cancer 2010;54:1048–1049 © 2010 Wiley‐Liss, Inc.
Severity of health conditions identified in a pediatric cancer survivor program
Authors: Wasilewski‐Masker Karen , Mertens Ann C. , Patterson Briana , Meacham Lillian R. 
Published: January 2010

AbstractBackgroundThe Common Terminology Criteria for Adverse Events v3.0 (CTCAE) was designed for reporting acute and late effects of cancer treatment. To date, no study of pediatric‐aged cancer survivors has graded health conditions using CTCAE, for patients in active follow‐up in a cancer survivor program.ProcedureMedical records were reviewed on 519 survivors of non‐central nervous system childhood malignancies seen in the Cancer Survivor Program between January 1, 2001 and December 15, 2005. Health problems identified through histories, physicals, and recommended evaluation using the Children's Oncology Group (COG) Long‐Term Follow‐Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancer were graded using the CTCAE.ResultsOverall, 1,625 adverse health conditions were reported or detected in 519 pediatric‐age cancer survivors (mean age at diagnosis 4.8 years; mean age at first survivor visit 12.1 years). The majority of conditions were mild (47.4% Grade 1) or moderate (35.2% Grade 2); however, 17.4% of conditions were severe (Grade 3) or life‐threatening/disabling (Grade 4). Only 12.1% of survivors had no adverse condition, and 36.2% of survivors had a Grade 3 or 4 condition. In a Cox multivariate analysis risk factors for a Grade 3 or 4 condition included minority race, diagnosis of other malignancy, older age, and a history of a hematopoietic stem cell transplant.ConclusionsThe majority of adverse health conditions in pediatric‐aged cancer survivors are mild; however, a significant percentage will have a serious condition. Long‐term follow‐up with a multidisciplinary approach is essential to detect and intervene in health problems early. Pediatr Blood Cancer 2010;54:976–982 © 2010 Wiley‐Liss, Inc.
Theoretical study on structures and vibrational spectra of M+(H2O)Ar (M = Cu, Ag, Au)
Authors: Song Xiudan , Zhao Yongfang , Zhang Pingxia , Zhang Guohua 
Published: January 2010

AbstractA theoretical study on the structures and vibrational spectra of M+(H2O)Ar0‐1 (M = Cu, Ag, Au) complexes was performed using ab initio method. Geometrical structures, binding energies (BEs), OH stretching vibrational frequencies, and infrared (IR) absorption intensities are investigated in detail for various isomers with Ar atom bound to different binding sites of M+(H2O). CCSD(T) calculations predict that BEs are 14.5, 7.5, and 14.4 kcal/mol for Ar atom bound to the noble metal ion in M+(H2O)Ar (M = Cu, Ag, Au) complexes, respectively, and the corresponding values have been computed to be 1.5, 1.3, and 2.1 kcal/mol when Ar atom attaches to a H atom of water molecule. The former structure is predicted to be more stable than the latter structure. Moreover, when compared with the M+(H2O) species, tagging Ar atom to metal cation yields a minor perturbation on the IR spectra, whereas binding Ar atom to an OH site leads to a large redshift in OH stretching vibrations. The relationships between isomers and vibrational spectra are discussed. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
Multiphoton association reaction He + H+ → HeH+ steered by ultra‐short laser pulse
Authors: Niu Ying‐Yu , Wang Rong , Qiu Ming‐Hui , Xiu Jun‐Ling 
Published: January 2010

AbstractThe multiphoton association reaction He + H+ → HeH+ in the electronic ground state is investigated using the time‐dependent quantum wave packet method. It is shown that the collision pairs He + H+ in continuum state transfer into ν = 0 state and then produce stable molecules HeH+ through emission of two or three photons. The multiphoton transition takes place via intermediate states, and the transfer probability is determined by the collision energy and the intermediate states. The populations of the intermediate states and ν = 0 state can be controlled by the laser duration. The three‐photon transition is more efficient than the two‐photon transition for producing the molecule HeH+ in ν = 0 state. © 2010 Wiley Periodicals, Inc. Int J Quantum Chem, 2011
An Easy Shortcut Synthesis of Size‐Controlled Bismuth Nanoparticles and Their Use in the SLS Growth of High‐Quality Colloidal Cadmium Selenide Quantum Wires
Authors: Wang Fudong , Buhro William E. 
Published: January 2010

AbstractAn easy shortcut synthesis of thermally stable, near‐monodisperse Bi nanoparticles from BiCl3 and Na[N(SiMe3)2] is described. The diameters of the Bi nanoparticles are controlled in the range of 4–29 nm by varying the amounts of BiCl3 and Na[N(SiMe3)2] employed. Standard deviations in their diameter distributions are 5–15% of the mean diameters, consistent with near monodispersity. These Bi nanoparticles are shown to be the best currently available catalysts for the solution–liquid–solid (SLS) growth of high‐quality CdSe quantum wires.
Crystal Structure of Molybdenum Tantalum Oxide, Mo2Ta2O11
Authors: Berendts Stefan , Stork Alexandra , Irran Elisabeth , Lerch Martin 
Published: January 2010

AbstractThe ternary molybdenum tantalum oxide Mo2Ta2O11 was synthesized through two different experimental routes. The crystal structure was determined from X‐ray powder diffraction data. Mo2Ta2O11 crystallizes in space group R\bar{3}m (no. 166) with the lattice parameters a = 562.82(2) pm and c = 2516.2(1) pm in hexagonal setting. A so far unknown layered structure with three formula units per unit cell is observed. Corner sharing TaO6 octahedra form double layers perpendicular to [001] with MoO4 tetrahedra on each side. The tetrahedra are connected by corners to the TaO6 octahedra and are isolated from each other. The crystal structure can be described in relation to the ReO3‐type.
Syntheses, Crystal Structures, Vibrational Spectra and 31P MAS NMR Spectra of the Thiophosphates NaM(PO3S)·9H2O (M = Ca, Ba)
Authors: Kazmierczak Karolina , Heck Joachim G. , Höppe Henning A. 
Published: January 2010

AbstractNaBa(PO3S)·9H2O was obtained as single‐phase crystalline powder starting from NaOH, PSCl3 and BaCl2. Single‐crystals of NaCa(PO3S)·9H2O were grown by a gel crystallisation technique. The crystal structures of NaCa(PO3S)·9H2O (P213, Z = 4, a = 10.7845(12) Å, R1 = 0.034, wR2 = 0.083, 711 reflections, 64 parameters) and NaBa(PO3S)·9H2O (P213, Z = 4, a = 11.0216(2) Å, 754 reflections, 2θmax = 70.0° RF2 = 0.099, Rp = 0.034, wRp = 0.047, χ2 = 3.34) are isotypic with that of NaSr(PO3S)·9H2O and these three are homeotypic with NaMPO4·9H2O (M = Sr, Ba). The crystal structures of NaM(PO3S)·9H2O (M = Ca, Ba) consist of isolated (PO3S) tetrahedra, [NaO6] distorted octahedra and [MO9] polyhedra with the latter forming a network according to {}^3_\infty[{Na(H2O)6/2}{Ca(H2O)6/2(H2O)3}]3+. Nine crystal water molecules are situated in the voids of the resulting structure. The vibrational spectra of the title compounds have been measured and the relevant bands were assigned. Solid‐state 31P MAS NMR spectra gave chemical shifts of 49 ppm for NaCa(PO3S)·9H2O, 34 ppm for NaBa(PO3S)·9H2O and 38 ppm for Na3(PO3S).
Synthesis and Crystal Structure of Novel Coordination Polymers with Nitrilotripropionic Acid
Authors: Xie Yan , Bai Feng‐Ying , Xing Yong‐Heng , Wang Zhuo , Zhao Hai‐Yan , Shi Zhan 
Published: January 2010

AbstractA novel three‐dimensional (3D) lanthanide‐organic framework [Pr3(NTP)3(H2O)6]·10H2O (1), (H3NTP = 3,3′,3′‐nitrilotripropionic acid) was synthesized and characterized by elemental analyses, IR spectroscopy, and X‐ray diffraction analyses. The results show that complex 1 is connected through NTP ligands to form a 3D network with microchannels. The coordination mode of the NTP ligand was found for the first time. In order to investigate the temperature effects on controlling the dimensionality of the complexes, another two complexes, namely, [Nd(NTP)(H2O)2]·H2O·HBr (2) and [Pr(H2O)][+NH3(CH2CH2COO–)][OOCCOO]1.5 (3) were synthesized and characterized. Notably, in complex 3, the NTP ligand lost its two arms because of the high temperature. Furthermore, the thermogravimetric analyses of the three complexes are discussed in detail.
New Energetic Materials featuring Tetrazoles and Nitramines – Synthesis, Characterization and Properties
Authors: Fischer Niko , Karaghiosoff Konstantin , Klapötke Thomas M. , Stierstorfer Jörg 
Published: January 2010

AbstractThe alkylation of 2‐nitro‐2‐azapropyl chloride (2) and deprotonated 5‐amino‐1H‐tetrazole (3), 1H‐tetrazole (4), 5‐nitrimino‐1,4H‐tetrazole (5), 1‐methyl‐5‐nitrimino‐4H‐tetrazole (6) and 2‐methyl‐5‐nitraminotetrazole (7) afforded the products 1‐(2‐nitro‐2‐azapropyl)‐5‐aminotetrazole (8), 1‐(2‐nitro‐2‐azapropyl)‐5H‐tetrazole (9), 1‐(2‐nitro‐2‐azapropyl)‐5‐nitriminotetrazole·H2O (10a), 1‐(2‐nitro‐2‐azapropyl)‐5‐nitriminotetrazole·EtOH (10b) 1,5‐bis(2‐nitro‐2‐azapropyl)‐5‐nitraminotetrazole (11), 1‐methyl‐5‐(2‐nitro‐2‐azapropyl)‐5‐nitraminotetrazole (12), 1‐methyl‐4‐(2‐nitro‐2‐azapropyl)‐5‐nitraminotetrazole (13), 1‐methyl‐5‐(2‐nitro‐2‐azapropyl)‐5‐aminotetrazole (14) and 2‐methyl‐5‐(2‐nitro‐2‐azapropyl)‐5‐nitraminotetrazole (15). In addition, the reaction of potassium 1‐methyl‐5‐nitriminotetrazolate with dimethyl sulfate was investigated yielding 1,4‐dimethyl‐5‐nitriminotetrazole (16). All products (8–16) were determined by low temperature single X‐ray diffraction. A comprehensive characterization and description of the chemical properties (IR, Raman, and multinuclear (1H, 13C and 15N) NMR spectroscopy, mass spectrometry, elemental analysis and differential scanning calorimetry) is given. The heats of formation were calculated by heats of combustion measured using bomb calorimetry. With these values and the X‐ray densities, several detonation parameters (e.g. detonation pressure, detonation velocity, heat of explosion) were computed by the EXPLO5 software. In addition, the sensitivities towards impact, friction and electrical discharge were determined.
Effects of diet on the chemical composition of migratory locusts (Locusta migratoria)
Authors: Oonincx D. G. A. B. , van der Poel A. F. B. 
Published: January 2010

AbstractAn experiment was conducted to determine the effects of diet on the chemical composition of migratory locusts (Locusta migratoria L.). Fresh and dry weight and the contents of dry matter, ash, lipid, protein, Ca, K, Mg, Na, P, Cu, Fe, Zn, retinol, lutein, zeaxanthine, cryptoxanthin, carotenes, lycopene and gross energy were determined in penultimate instar and adult locusts, that had been fed three different diets. The locusts received a diet of grass or grass+wheat bran or grass+wheat bran+carrots. Adding wheat bran decreased the protein content and increased fat content (633 vs. 583 and 182 vs. 231 g/kg DM, respectively). Addition of carrots to the diet increased fat content further from 231 to 271 g/kg DM. Mineral concentrations of Ca, K, Mg, and Na, were significantly affected by diet. P, K, Cu, and Fe concentrations were significantly different in penultimate migratory locusts compared with adults. Wheat bran decreased the α‐carotene content, which did not change by incorporating carrots in the diet. However, carrots did result in higher β‐carotene concentrations. Retinol concentrations were increased by incorporating both wheat bran and carrots in the diet compared with the diet containing only grass. This study shows that the chemical composition of migratory locusts can be manipulated through the diet. As such, it enables nutritionists to adapt the chemical composition of live feeder insects to better meet the nutritional demands of predators. Zoo Biol 30:9–16, 2011. © 2010 Wiley‐Liss, Inc.
Presentation and Survival of Operable Esophageal Cancer in Patients 55 Years of Age and Below
Authors: Hamouda A. , Forshaw M. , Rohatgi A. , Mirnezami R. , Botha A. , Mason R. 
Published: January 2010

AbstractBackgroundThe increased incidence of esophageal cancer, especially in the younger age group, should encourage early diagnosis. The perceived rarity and poor prognostic outcome of esophageal cancer in this group is based on retrospective studies. The goal of this study was to review the presentation and survival of young patients with esophageal cancer.MethodsThis study was conducted from 2000 to 2007 in a specialized esophagogastric center. All patients who had esophageal cancer operations were included. Variables collected included ages, duration of symptoms, presenting symptoms, tumor characteristics, and follow‐up data.ResultsIn total, 365 esophagectomies were performed for cancer, of which 76 patients were younger than aged 55 years (20.8%) and 289 were older than aged 55 years. In patients younger than aged 55 years, 15 patients had symptoms for 6 months or more, 54 had dysphagia, 35 had weight loss compared with 220 and 175 respectively of patients older than aged 55 years. On histopathology, 48 had T3 tumors (63.2%), 17 had T2 (22.4%), and 10 had T1 (13.2%) for patients younger than aged 55 years compared with 141 had T3 (48.7%), 85 had T2 (29.4%), and 55 had T1 (19%) for patients older than aged 55 years. These differences in tumor stage at presentation between groups were significant (p < 0.05 with 3DF). In‐hospital mortality was 0 for the group younger than aged 55 years and 5 for those older than aged 55 years. Average follow‐up was 35 (minimum, 15) months. Thirty patients had locoregional recurrence in the first group and 110 in the latter group. Survival at 1 year after surgery was 79.6%, at 2 years 65.1%, and at 5 years 42.3% compared with 78.4, 60.6, and 45.9%, respectively, for the group older than aged 55 years, but this was not significant using log‐rank (p = 0.99).ConclusionsA significant proportion (20.8%) of patients presenting with operable esophageal cancer was younger than aged 55 years. Almost two‐thirds of those presenting younger than aged 55 years had T3 stage tumors, which was significantly different than those older than aged 55 years. Despite more advanced tumor stage at presentation, the prognosis of esophageal cancer for patients younger than aged 55 years is similar to those older than aged 55 years (log‐rank = 0.99).
MAXIMAL ANNULI WITH PARALLEL PLANAR BOUNDARIES IN THE THREE-DIMENSIONAL LORENTZ–MINKOWSKI SPACE
Authors: PYO JUNCHEOL 
Published: January 2010

AbstractWe prove that maximal annuli in 𝕃3bounded by circles, straight lines or cone points in a pair of parallel spacelike planes are part of either a Lorentzian catenoid or a Lorentzian Riemann’s example. We show that under the same boundary condition, the same conclusion holds even when the maximal annuli have a planar end. Moreover, we extend Shiffman’s convexity result to maximal annuli; but by using Perron’s method we construct a maximal annulus with a planar end where a Shiffman-type result fails.