bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performative agency and transition in Àlàbí Ògúndépò’s ìjálá and Yẹmí Ẹlẹ́buìbọn’s Ifá chants
Authors: Adeduntan Ayo 
Published: May 2024

AbstractIndigenous Yorùbá poetry is often defined by such features as context, structure, tonal quality and the performer’s identity. Early taxonomy of the poetry focused on the poetics that could be deduced from a long tradition of practice. Recent scholarship in literary and cultural studies has been more interested in showing the ways in which the poetry is being inflected by encounters with postcolonial modernity. While these recent contributions demonstrate how new forms, such as ewì, distil expressive nuances from the older forms and invent new performative practices to address new publics, such studies encourage a generalization that credits to the new forms all the modern advances recorded in the indigenous forms themselves. Looking at specific indigenous forms in terms of how postcolonial modernity has reshaped them, rather than considering them another set of additions to a new generic category, allows us a clearer view of their transition. I track the inventions and changes in the practice of two Yorùbá forms, ìjálá and Ifá chants, using the performances of Àlàbí Ògúndépò and Yẹmí Ẹlẹ́buìbọn. I rely on ethnographic data to show how mutating audiences and electronic storage and retrieval systems have continually shaped composition and performance, discuss the imperatives of modernity and economy in the performative choices of the artists, and show how the performers simultaneously manage their resistance to and adoption of the modern.
Intimacy, comradeship and everyday police violence: the rape of Sophie M. in German South West Africa in 1910
Authors: Muschalek Marie A. 
Published: May 2024

AbstractThis article asks whether and how gendered violence was part of the quotidian activity of state building in German South West Africa. Investigating the intimate space of a police compound, it gives a micro-historical account of how interracial sexual relations unfolded there, and how policemen’s private, intimate affairs were subject to close scrutiny by the colonial state. Rape – as distinctively masculine violence – posed a notably delicate problem to the legitimacy of the colonial state. The white masculine prerogative needed to be affirmed as the raison d’être of the colonial regime, but disorderly, unprofessional violence had to be controlled for the same reason. The case examined in this article was a rare moment in which an African woman attempted to take part in the discussion over the meaning of sex and violence. Ultimately, her articulation of what intimate, physical interactions meant to her was ignored. Instead, policemen articulated what masculine honour and comradeship meant to them. These discussions over what individual ‘honourable’ (including violent) behaviour implied were also always negotiations over the nature of colonial power and its programme.
Direct and maternal genetic parameters for growth traits in Jersey crossbred cattle
Authors: Vangchhia Nunhlupuii , Gayari Indrajit , Rahman Mokidur , Lalhmingmawii Sylvia , Bhakat Champak , Baneh Hasan , Mandal Ajoy 
Published: May 2024

AbstractGrowth data on Jersey crossbred calves, maintained at ICAR-National Dairy Research Institute, Eastern Regional Station, Kalyani, Nadia, West Bengal, India, were collected and analysed to assess the influence of maternal effects on growth traits of calves. Traits considered for this study were birth weight (BW) and weights at 3 months (W3M), 6 months (W6M), 9 months (W9M) and 12 months (W12M) of age. Least-squares analyses were employed to obtain the effects of non-genetic factors on the traits of interest. Determination of influence of maternal effects on growth traits was estimated by fitting three univariate animal models (including or excluding maternal effects) using Bayesian approach. The most appropriate model for each trait was selected based on Deviance Information Criterion. Direct heritability (h2) estimates for BW, W3M, W6M, W9M and W12M were 0.31 ± 0.08, 0.26 ± 0.10, 0.48 ± 0.10, 0.44 ± 0.11 and 0.39 ± 0.14, respectively, under the best model. Permanent environmental maternal effects (c2) varied from 0.04 to 0.12 for all traits. Existence of maternal effects for all ages reflects the importance of maternal components for these traits. Moderate to high heritability estimates for growth traits indicate the possibility of modest genetic progress for these traits through selection under prevalent management system.
Data on four species of Longidorus Micoletzky, 1922 (Nematoda: Longidoridae) from southern and southeastern Iran, including description of a new species
Authors: Monemi S. , Behdani M. , Mahdikhani-Moghadam E. , Amirzadi N. , Atighi M. R. , Ye W. , Jahanshahi Afshar F. , Pedram M. 
Published: May 2024

Abstract
Four species of the genus Longidorus were recovered from southern (Bushehr province) and southeastern (Southern Khorasan province) Iran. The first species, L. paratabrizicus n. sp. represents a new member to the genus and is characterised by 4.8–5.6 mm long females with anteriorly flattened lip region separated from the rest of the body by depression, amphidial fovea pocket-shaped without lobes, tail conical, dorsally convex, ventrally almost straight with bluntly rounded tip and males in population. By having similar lip region and tail shape, the new species most closely resembles five species viz. L. artemisiae, L. globulicauda, L. patuxentensis, L. sturhani, and L. tabrizicus. It represents the cryptic form of the last species. The second species belongs to L. mirus, recovered in both southern and southeastern Iran, representing the first record of the species after its original description. As an update to the characteristics of this species, it’s all juvenile developmental stages were recovered and described. The criteria to separate L. mirus from two closely related species, L. auratus and L. africanus, are discussed. The third species belongs to L. persicus, a new record in southern Iran. The fourth species, L. orientalis was recovered in high population density in association with date palm trees in Bushehr province. The phylogenetic relationships of the new species and recovered populations of L. mirus and L. persicus were reconstructed using two ribosomal markers and the resulted topologies were discussed.
A large cryptosporidiosis outbreak associated with an animal contact event in England: a retrospective cohort study, 2023
Authors: Peake Lewis , Bardsley Megan , Bartram Samantha , Bharuchi Shireen , Howkins Josh , Robinson Guy , Charlett André , Chalmers Rachel , Bird Sarah , Young Nick 
Published: May 2024

Abstract
Development of gastrointestinal illness after animal contact at petting farms is well described, as are factors such as handwashing and facility design that may modify transmission risk. However, further field evidence on other behaviours and interventions in the context of Cryptosporidium outbreaks linked to animal contact events is needed. Here, we describe a large outbreak of Cryptosporidium parvum (C. parvum) associated with a multi-day lamb petting event in the south-west of England in 2023 and present findings from a cohort study undertaken to investigate factors associated with illness. Detailed exposure questionnaires were distributed to email addresses of 647 single or multiple ticket bookings, and 157 complete responses were received. The outbreak investigation identified 23 laboratory-confirmed primary C. parvum cases. Separately, the cohort study identified 83 cases of cryptosporidiosis-like illness. Associations between illness and entering a lamb petting pen (compared to observing from outside the pen; odds ratio (OR) = 2.28, 95 per cent confidence interval (95% CI) 1.17 to 4.53) and self-reported awareness of diarrhoeal and vomiting disease transmission risk on farm sites at the time of visit (OR = 0.40, 95% CI 0.19 to 0.84) were observed. In a multivariable model adjusted for household clustering, awareness of disease transmission risk remained a significant protective factor (adjusted OR (aOR) = 0.07, 95% CI 0.01 to 0.78). The study demonstrates the likely under-ascertainment of cryptosporidiosis through laboratory surveillance and provides evidence of the impact that public health messaging could have.
Pathways to adolescent social anxiety: Testing interactions between neural social reward function and perceived social threat in daily life
Authors: Sequeira Stefanie L. , Silk Jennifer S. , Jones Neil P. , Forbes Erika E. , Hanson Jamie L. , Hallion Lauren S. , Ladouceur Cecile D. 
Published: May 2024

Abstract
Recent theories suggest that for youth highly sensitive to incentives, perceiving more social threat may contribute to social anxiety (SA) symptoms. In 129 girls (ages 11–13) oversampled for shy/fearful temperament, we thus examined how interactions between neural responses to social reward (vs. neutral) cues (measured during anticipation of peer feedback) and perceived social threat in daily peer interactions (measured using ecological momentary assessment) predict SA symptoms two years later. No significant interactions emerged when neural reward function was modeled as a latent factor. Secondary analyses showed that higher perceived social threat was associated with more severe SA symptoms two years later only for girls with higher basolateral amygdala (BLA) activation to social reward cues at baseline. Interaction effects were specific to BLA activation to social reward (not threat) cues, though a main effect of BLA activation to social threat (vs. neutral) cues on SA emerged. Unexpectedly, interactions between social threat and BLA activation to social reward cues also predicted generalized anxiety and depression symptoms two years later, suggesting possible transdiagnostic risk pathways. Perceiving high social threat may be particularly detrimental for youth highly sensitive to reward incentives, potentially due to mediating reward learning processes, though this remains to be tested.
The use of artificially intelligent chatbots in English language learning: A systematic meta-synthesis study of articles published between 2010 and 2024
Authors: Koç Fatma Şeyma , Savaş Perihan 
Published: May 2024

AbstractIn this qualitative systematic meta-synthesis study, 57 studies from the international literature published between 2010 and 2024 on the use of voice-based artificially intelligent chatbots in English language learning were analyzed. The present study aimed to explore the most recent studies on this topic by investigating the theoretical frameworks, methodological and technological properties, user reports of chatbot usage experience, and pedagogical implementations. It sought to identify research and implementation trends for voice-based chatbots via qualitative data analysis methods. Based on the reviewed studies, this paper presents data-based pedagogical implications that align with the latest voice-based AI chatbot research trends.
Rapid Acceleration Bursts in the Van Allen Radiation Belt
Authors: Olifer L. , Morley S. K. , Ozeke L. G. , Mann I. R. , Kalliokoski M. M. H. , Henderson M. G. , Carver M. R. , Hoover A. 
Published: May 2024

AbstractThe fast Van Allen radiation belt electron dynamics during geomagnetic storms have not yet been fully explained, in part due to limitations of standard satellite missions in both orbit and the number of spacecraft. Here we overcome these limitations using measurements from the Global Positioning System (GPS) constellation during an acceleration event on 26 August 2018. We show that the acceleration of relativistic electrons occurs in two distinct bursts, each dominated by a different acceleration mechanism. The first burst enhances the radiation belt electrons by four orders of magnitude in 2 hr and is consistent with ULF‐wave radial diffusion. The second burst is likely caused by the local acceleration and delivers an order‐of‐magnitude increase in 20 min. This work demonstrates how distributed, operational measurements can be used to resolve phenomena not observable with previous capabilities, and that rapid energization of the radiation belt can occur much faster than previously reported.
A Taxonomy of Upper‐Mantle Stratification in the US
Authors: Carr Steve A. B. , Olugboji Tolulope 
Published: May 2024

AbstractThe investigation of upper mantle structure beneath the US has revealed a growing diversity of discontinuities within, across, and underneath the sub‐continental lithosphere. As the complexity and variability of these detected discontinuities increase—for example, velocity increase/decrease, number of layers and depth—it is hard to judge which constraints are robust and which explanatory models generalize to the largest set of constraints. Much work has been done to image discontinuities of interest using S‐waves that convert to P‐waves (or top‐side reflected SS waves). A higher resolution method using P‐to‐S scattered waves is preferred but often obscured by multiply reflected waves trapped in a shallower layer, limiting the visibility of deeper boundaries. Here, we address the interference problem and re‐evaluate upper mantle stratification using filtered P‐to‐S receiver functions (Ps‐RFs) interpreted using unsupervised machine‐learning. Robust insight into upper mantle layering is facilitated with CRISP‐RF: Clean Receiver‐Function Imaging using Sparse Radon Filters. Subsequent sequencing and clustering organizes the polarity‐filtered Ps‐RFs into distinct depth‐based clusters. We find three types of upper mantle stratification beneath the old and stable continental US: (a) intra‐lithosphere discontinuities (paired or single boundary), (b) transitional discontinuities (single boundary or with a top layer), and (c) sub‐lithosphere discontinuities. Our findings contribute a more nuanced understanding of mantle discontinuities, offering new perspectives on the nature of upper mantle layering beneath continents.
Disease-specific alterations in central fear network engagement during acquisition and extinction of conditioned interoceptive fear in inflammatory bowel disease
Authors: Lanters Laura R. , Öhlmann Hanna , Langhorst Jost , Theysohn Nina , Engler Harald , Icenhour Adriane , Elsenbruch Sigrid 
Published: May 2024

AbstractInteroceptive fear, which is shaped by associative threat learning and memory processes, plays a central role in abnormal interoception and psychiatric comorbidity in conditions of the gut-brain axis. Although animal and human studies support that acute inflammation induces brain alterations in the central fear network, mechanistic knowledge in patients with chronic inflammatory conditions remains sparse. We implemented a translational fear conditioning paradigm to elucidate central fear network reactivity in patients with quiescent inflammatory bowel disease (IBD), compared to patients with irritable bowel syndrome (IBS) and healthy controls (HC). Using functional magnetic resonance imaging, conditioned differential neural responses within regions of the fear network were analyzed during acquisition and extinction learning. In contrast to HC and IBS, IBD patients demonstrated distinctly altered engagement of key regions of the central fear network, including amygdala and hippocampus, during differential interoceptive fear learning, with more pronounced responses to conditioned safety relative to pain-predictive cues. Aberrant hippocampal responses correlated with chronic stress exclusively in IBD. During extinction, differential engagement was observed in IBD compared to IBS patients within amygdala, ventral anterior insula, and thalamus. No group differences were found in changes of cue valence as a behavioral measure of fear acquisition and extinction. Together, the disease-specific alterations in neural responses during interoceptive fear conditioning in quiescent IBD suggest persisting effects of recurring intestinal inflammation on central fear network reactivity. Given the crucial role of interoceptive fear in abnormal interoception, these findings point towards inflammation-related brain alterations as one trajectory to bodily symptom chronicity and psychiatric comorbidity. Patients with inflammatory conditions of the gut-brain axis may benefit from tailored treatment approaches targeting maladaptive interoceptive fear.
The influence of acute lifestyle changes on NAFLD evolution in a multicentre cohort: a matter of body composition
Authors: Dallio Marcello , Sangineto Moris , Romeo Mario , Cipullo Marina , Coppola Annachiara , Mammone Simone , Di Gioia Giuseppe , Masarone Mario , Persico Marcello , Serviddio Gaetano , Federico Alessandro 
Published: May 2024

Abstract
Background
Unhealthy lifestyles represent a key element fueling Non-alcoholic fatty liver disease (NAFLD) onset and worsening. We aimed to evaluate the effects of forced acute lifestyle changes on NAFLD evolution.

Methods
187 NAFLD patients were followed two years pre- and two years during the lockdown social restrictions in three Italian medical centers. For each patient, biochemical, clinical, non-invasive liver fibrosis, nutritional, and body composition data were collected.

Results
An increase in fats and carbohydrate intake associated with impaired weekly physical activity during the lockdown was demonstrated as well as an increase in body mass index and waist-hip-ratio (p < 0.0001 for all). Total cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, glucose, insulin, homeostatic model assessment for insulin resistance, and transaminases worsened during the lockdown (glucose: p = 0.0007; p < 0.0001 for the others). Moreover, NAFLD fibrosis score, liver stiffness, and controlled attenuation parameter were also impaired during the same period (p < 0.0001 for all). The bioelectrical impedance analysis (BIA) evidenced an increase of fat mass (FM), and a reduction of free fat mass (FFM) and body cell mass (BCM) (p < 0.0001 for all). The lockdown overall hepatocellular carcinoma (HCC) and Milan-out HCC occurrence revealed Hazard Ratio (HR): 2.398, 95% Confidence Interval (CI):1.16–5, p = 0.02, and HR:5.931, CI:2–17.6, p = 0.008 respectively. A liver disease stage and comorbidities independent association between both the assessed outcomes and body composition analysis in terms of mean values and variation (T1–T2 Δ) was demonstrated.

Conclusions
The acute lifestyle changes impacted NAFLD evolution via body composition modifications negatively influencing the HCC occurrence.
Notch signaling pathway in cancer: from mechanistic insights to targeted therapies
Authors: Shi Qingmiao , Xue Chen , Zeng Yifan , Yuan Xin , Chu Qingfei , Jiang Shuwen , Wang Jinzhi , Zhang Yaqi , Zhu Danhua , Li Lanjuan 
Published: May 2024

AbstractNotch signaling, renowned for its role in regulating cell fate, organ development, and tissue homeostasis across metazoans, is highly conserved throughout evolution. The Notch receptor and its ligands are transmembrane proteins containing epidermal growth factor-like repeat sequences, typically necessitating receptor-ligand interaction to initiate classical Notch signaling transduction. Accumulating evidence indicates that the Notch signaling pathway serves as both an oncogenic factor and a tumor suppressor in various cancer types. Dysregulation of this pathway promotes epithelial-mesenchymal transition and angiogenesis in malignancies, closely linked to cancer proliferation, invasion, and metastasis. Furthermore, the Notch signaling pathway contributes to maintaining stem-like properties in cancer cells, thereby enhancing cancer invasiveness. The regulatory role of the Notch signaling pathway in cancer metabolic reprogramming and the tumor microenvironment suggests its pivotal involvement in balancing oncogenic and tumor suppressive effects. Moreover, the Notch signaling pathway is implicated in conferring chemoresistance to tumor cells. Therefore, a comprehensive understanding of these biological processes is crucial for developing innovative therapeutic strategies targeting Notch signaling. This review focuses on the research progress of the Notch signaling pathway in cancers, providing in-depth insights into the potential mechanisms of Notch signaling regulation in the occurrence and progression of cancer. Additionally, the review summarizes pharmaceutical clinical trials targeting Notch signaling for cancer therapy, aiming to offer new insights into therapeutic strategies for human malignancies.
Trends in cancer-related suicide in the United States: a population-based epidemiology study spanning 40 years of data
Authors: Liu Qiang , Qu Zheng , Dong Hao , Qi Yihang , Wu Juan , Zhang Wenxiang , Wang Xiangyu , Wang Zhongzhao , Fang Yi , Wang Jing 
Published: May 2024

AbstractLarge cohort studies examining trends in cancer-related suicide are lacking. We analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database, encompassing a total of 4,870,410 patients diagnosed with cancer from 1975 to 2017 in the United States. Joinpoint regression was used to estimate the annual percent change (APC) and average annual percentage change (AAPC) of age-adjusted rates of suicide. In the past 40 years, we revealed a gradual increase in cancer-related suicide rates from 1975 to 1989, followed by a gradual decrease from 1989 to 2013, and a marked decrease from 2013 to 2017. These trends suggested the potential impact of advancements in psychosocial care for patients with cancer in contributing to the observed decrease in suicide rates.
A novel mutation of DNA2 regulates neuronal cell membrane potential and epileptogenesis
Authors: Liu Yuting , Yang Haiyan , Gan Siyi , He Lu , Zeng Rongrong , Xiao Ting , Wu Liwen 
Published: May 2024

AbstractMesial temporal lobe epilepsy (MTLE) is one of the most intractable epilepsies. Previously, we reported that mitochondrial DNA deletions were associated with epileptogenesis. While the underlying mechanism of mitochondrial DNA deletions during epileptogenesis remain unknown. In this study, a novel somatic mutation of DNA2 gene was identified in the hippocampal tissue of two MTLE patients carrying mitochondrial DNA deletions, and this mutation decreased the full-length expression of DNA2 protein significantly, aborting its normal functions. Then, we knocked down the DNA2 protein in zebrafish, and we demonstrated that zebrafish with DNA2 deficiency showed decreased expression of mitochondrial complex II–IV, and exhibited hallmarks of epileptic seizures, including abnormal development of the zebrafish and epileptiform discharge signals in brain, compared to the Cas9-control group. Moreover, our cell-based assays showed that DNA2 deletion resulted in accumulated mitochondrial DNA damage, abnormal oxidative phosphorylation and decreased ATP production in cells. Inadequate ATP generation in cells lead to declined Na+, K+-ATPase activity and change of cell membrane potential. Together, these disorders caused by DNA2 depletion increased cell apoptosis and inhibited the differentiation of SH-SY5Y into branched neuronal phenotype. In conclusion, DNA2 deficiency regulated the cell membrane potential via affecting ATP production by mitochondria and Na+, K+-ATPase activity, and also affected neuronal cell growth and differentiation. These disorders caused by DNA2 dysfunction are important causes of epilepsy. In summary, we are the first to report the pathogenic somatic mutation of DNA2 gene in the patients with MTLE disease, and we uncovered the mechanism of DNA2 regulating the epilepsy. This study provides new insight into the pathogenesis of epilepsy and underscore the value of DNA2 in epilepsy.