bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonparametric Statistical Analysis of the Reliability of a Naval Aviation Propulsion System
Authors: MILLAR RICHARD C. , MAZZUCHI THOMAS ANDREW , SARKANI SHAHRAM 
Published: September 2009

AbstractThis paper reports the results of applying lifetime (or reliability database) statistical analysis methods to engine removal data recorded over the initial 8 years' service of the General Electric F414‐GE‐400 turbofan engines propelling the F/A‐18 E/F Super Hornet in service with the US Navy, with the intent of better understanding the reasons for engine removal and their impact on engine time on wing (TOW), and to gain an insight into the reliability of the modules and components from which the engine is assembled. It was found that “coloring” the engine removals into three classes of reasons for removal enabled lifetime data analysis revealing interesting and useful features of in‐service engine reliability. Nonparametric statistical analysis provided actionable information on engine removal probability as a function of TOW and removal cause that should be applicable to planning flight operations, line maintenance, and support logistics. The analysis of engine removals due to hot section distress appears to disconfirm the presumption of independence between the three classes of removal. Opportunistic maintenance of modules made accessible due to engine removals to service other modules may significantly affect the observed engine removal distribution of the module of interest, i.e., competing risk masks the underlying module hazard functions.
Clinical and radiographic study of implant treatment outcome in periodontally susceptible and non‐susceptible patients: a prospective long‐term study
Authors: De Boever Annemarie L. , Quirynen Marc , Coucke Wim , Theuniers Guy , De Boever Jan A. 
Published: September 2009

AbstractObjectives: To evaluate the implant survival rate, periodontal and radiographic parameters of non‐submerged screw implants with two different surfaces (TPS and SLA) in periodontally non‐susceptible patients (NSP) and in patients with chronic adult periodontitis (CAP) or with generalized aggressive periodontitis (GAP).Material and methods: In 110 healthy partially edentulous subjects, 68 patients with CAP and 16 patients with GAP, a total of 513 implants were installed and followed for on average 48.1±25.9 months. Only fixed partial dentures were used as suprastructures. All patients were offered a supportive periodontal maintenance program. Smoking habits, health impairment, plaque score, bleeding on probing (BOP), type of surface, bone score, bone loss on radiographs and the number of failed implants were noted.Results: Implant survival in the NSP and CAP group was 98% and 96% after 140 months (NS), but only 80% after 100 months in the GAP group (P=0.0026). The overall rate of implant loss was 4.7%, but 15.25% in the GAP group (6/16 patients). The average marginal bone loss for all implants was 0.12±0.71 mm on the mesial side and 0.11±0.68 mm on the distal side. Bone loss/year was 0.08±0.31 and 0.07±0.3 mm in the NSP group, but 0.17±0.2 and 0.17±0.19 mm in the GAP group. Only in the GAP group, was bone loss significantly related to BOP, age, inflammation, presence of plaque, probing depth. Implants with a TPS surface had a lower survival than implants with an SLA surface (93% vs. 97%; P=0.06), especially in the GAP group (80% vs. 83%; P=0.005). Smoking habits had a significant influence on implant survival only in the GAP group (P=0.07), declining in current smokers to 63%, and to 78% in former smokers. Overall, impaired general health had no significant influence (P=0.85). However, impaired health further reduced implant survival in the GAP group (survival: 71%). In a statistical model to predict the chance for implant failing, only periodontal classification (P=0.012) and implant surface type (P=0.027) were significant.Conclusion: Periodontally healthy patients and patients with CAP show no difference in peri‐implant variables and implant survival rate, but patients with GAP have more peri‐implant pathology, more marginal bone loss and a lower implant survival implant rate. SLA surface had a better prognosis than the TPS surface.
Is the osseointegration of immediately and delayed loaded implants the same?—comparison of the implant stability during a 3‐month healing period in a prospective study
Authors: Zhou Wei , Han Chun , Yunming Li , Li Dehua , Song Yingliang , Zhao Yimin 
Published: September 2009

AbstractObjectives: The objectives of the present study were (1) to compare the stability of delayed loaded (DL) and immediately loaded (IL) ITI SLA implants during the first 3 months of the healing period using resonance frequency analysis (RFA) and (2) to determine the factors that affect implant stability during the healing period.Materials and methods: To compare implant stability, RFA was performed on two groups of patients (12 patients received 25 IL implants and 47 patients received 79 DL implants) with a total 104 ITI SLA implants. Implant stability was measured directly by RFA at implant placement and consecutively once a week for 12 weeks. Statistical analyses were carried out to study implant stability differences between IL and DL groups.Results: One of the 25 implants in the IL group failed, and no implant was lost in the DL group. Implant stability between the IL and DL groups showed a statistically significant difference (P<0.05). The mean implant stability quotient of all measured implants from implant insertion to 12 weeks was 72.88 ± 5.39 for the DL and 75.86 ± 3.60 for the IL types. The lowest stability was at 4 weeks for DL implants (mean: 71.58 ± 5.11) and 2 weeks for IL implants (mean: 71.33 ± 2.97). In both groups, bone types I and II showed higher implant stability than bone type III (P<0.05).Conclusions: The findings of this study indicate that differences in osseointegration between IL and DL implants may be predicted according to differential implant stability.
Combined definition of seed transfer guidelines for ecological restoration in the French Pyrenees
Authors: Malaval S. , Lauga B. , Regnault‐Roger C. , Largier G. 
Published: September 2009

AbstractQuestion: Can genetic tools combined with phytogeography help to define local plants and how geographically close the source population should be to the restoration site?Location: Subalpine and alpine French Pyrenees.Methods: The main phytogeographic boundaries in the French Pyrenees described by different authors were studied and this geographic pattern was compared with the results of genetic analysis for the four Pyrenean plants studied (Trifolium alpinum, Festuca eskia, Festuca gautieri and Rumex scutatus), based on random amplified polymorphic DNA (RAPD) marker analysis, unweighted pair‐group method with arithmetic averages (UPGMA) analysis and Mantel correlograms comparing geographic and genetic distances.Results: The genetic analysis allowed definition of two main evolutionarily significant units (ESUs) for the plants under study. Although the limit between the two zones was slightly variable according to the species considered, an eastern and a western ESU was consistently observed. This delineation was concordant with the main phytogeographic boundaries of the French Pyrenees.Conclusion: RAPD markers and associated Mantel correlograms can be useful to draw ESUs for individual species when the sampling intensity is relatively dense, and similarities were revealed between species sharing the same distribution range. This delineation allowed integration of infraspecific plant variation in the management of natural resources for revegetation in the Pyrenees. Nevertheless, caution is needed for the establishment of seed pools in order to maximize genetic diversity in each of the pools during collection and production.
Erectile Dysfunction Severity as a Risk Predictor for Coronary Artery Disease
Authors: Salem Sepehr , Abdi Seifollah , Mehrsai Abdolrasoul , Saboury Babak , Saraji Ali , Shokohideh Vahid , Pourmand Gholamreza 
Published: September 2009

ABSTRACT

Introduction
Erectile dysfunction (ED) is now beginning to be considered as an early manifestation of a subclinical systemic vascular disorder and may be an index of subclinical coronary artery disease (CAD).

Aim
To further evaluate whether ED is a predicting factor for CAD while adjusting for other common risk factors.

Methods
One hundred eighty-three patients with newly diagnosed and documented CAD and 134 participants without CAD were enrolled in this case-control study at our referral center. Univariate and multivariate logistic regression analysis were performed to assess the effect of classic risk factors and ED severity on CAD; calculating odds ratio (OR) and 95% confidence interval (CI). Adjustments were made for potential confounding factors including age, hypertension, diabetes, dyslipidemia, obesity, and smoking.

Main Outcome Measures
The prevalence of ED and the distribution of CAD risk factors (age, smoking, lipid profile, hypertension, obesity, and diabetes mellitus) were evaluated. The 5-item International Index of Erectile Function was used to evaluate the presence and the severity of ED.

Results
The prevalence of ED in CAD-positive and CAD-negative groups was 88.5% and 64.2%, respectively (P &lt; 0.05). A statistically significant difference was found for all risk factors (except total cholesterol and low-density lipoprotein levels), and also ED prevalence between studied groups. Adjusted OR for age, diabetes, hypertension, hypercholesterolemia, and smoking demonstrated a significant confounding effect. Our results also revealed a significant association between severe ED and CAD (OR: 2.22, 95% CI: 1.11–6.03; P &lt; 0.05).

Conclusion
This study suggests that ED could be considered as a surrogate marker which can predict the occurrence of CAD, and severe ED could be regarded as an independent risk predictor in addition to the established ones.
Chronology of Erectile Function in Patients with Early Functional Erections Following Radical Prostatectomy
Authors: Katz Darren , Bennett Nelson E. , Stasi Jason , Eastham James A. , Guillonneau Bertrand D. , Scardino Peter T. , Mulhall John P. 
Published: September 2009

ABSTRACT

Introduction
The association between erectile dysfunction (ED) and radical prostatectomy (RP) is well established. It is our clinical experience that some men who have functional erections in the days to weeks after RP go on to lose erectile function (EF) after the first 3 months postsurgery.

Aim
To assess EF over a 12-month period in patients with functional erections at 3 months following RP.

Methods
As part of a large prospective quality-of-life (QOL) study of men undergoing RP at our institution, EF is measured postoperatively at regular time intervals using serial administration of the International Index of Erectile Function (IIEF) questionnaire. For study inclusion, patients had to have functional erections (a score 4 or 5 on IIEF question 3) at the third postoperative month, and have at least 12 months of follow-up.

Main Outcome Measures
Assessment of EF and phosphodiesterase type 5 inhibitor (PDE5i) use at 3, 6, and 12 months after RP.

Results
At 3 months, 76 of 482 patients (16%) had functional erections. Between 3 to 6 months postoperatively, 20% of men deteriorated in their functional status. Of these men, 91% had functional erections at 1 year. Comparing patients who did not require PDE5i to obtain a functional erection at 3 months with those who did, the EF outcomes were superior at 6 months (80% vs. 72%, P = 0.74) and 12 months (100% vs. 88%, P = 0.33).

Conclusion
The recovery of functional erections in the early postoperative phase, especially without the need for PDE5i, is a good prognostic indicator for EF at 12 months. However, a distinct cohort of men lose functional erections within 6 months after surgery. It is important to inform patients of this possibility, as it has an impact on their QOL and, potentially, on their compliance with post-RP therapy for ED.
Postoperative Orgasmic Function Increases over Time in Patients Undergoing Nerve-Sparing Radical Prostatectomy
Authors: Salonia Andrew , Gallina Andrea , Briganti Alberto , Colombo Renzo , Bertini Roberto , Da Pozzo Luigi F. , Zanni Giuseppe , Sacca Antonio , Rocchini Lorenzo , Guazzoni Giorgio , Rigatti Patrizio , Montorsi Francesco 
Published: September 2009

ABSTRACT

Introduction
Postprostatectomy orgasmic function (OF) remains poorly defined.

Aims
To assess OF over time in patients who underwent bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP) for organ-confined prostate cancer (PCa).

Methods
Baseline data were obtained from 334 consecutive preoperatively sexually active PCa patients at hospital admission; data included a medical and sexual history, IIEF domain scores, and ICIQ-SF. Questionnaire were then completed every 12 months postoperatively, and patients participated in a semistructured interview at the 12-month (191/334 [57.2%] patients), 24-month (95/334 [28.4%] patients), 36-month (42/334 [12.6%] patients), and 48-month (19/334 [5.7%] patients) follow-up (FU).

Main Outcome Measures
IIEF-OF domain values throughout the FU. Multivariate linear regression analysis (MVA) of the association between predictors (patient’s age, IIEF-erectile function [EF], ICIQ-SF, and the use of postoperative proerectile pharmacological treatments) and the IIEF-OF at 12-month, 24-month, and 36-month FU.

Results
Preoperative mean (median) IIEF-OF was 7.6 (10). The anova analysis showed an increase of the IIEF-OF values (P = 0.008; F = 4.009) throughout the FU (namely, IIEF-OF 12-month: 6.1 [6]; 24-month: 7.2 [8]; 36-month: 7.3 [8]; and 48-month: 7.7 [9.50]). The 12-month MVA showed that while proerectile oral therapy did not affect postoperative OF (P = 0.150; Beta 0.081), IIEF-OF linearly increased with IIEF-EF (P &lt;0.001; Beta 0.425). Conversely, IIEF-OF linearly decreased with patient’s age (P &lt;0.001; Beta −0.135) and with ICQ-SF scores (P &lt;0.001; Beta −0.438). The 24-month and 36-month analyses showed that IIEF-OF still linearly increased with IIEF-EF (P &lt;0.001; Beta 0.540, and P &lt;0.001; Beta 0.536 respectively at the 24- and 36-month FU), whereas pharmacological therapy, rate of urinary continence, and patient’s age did not significantly affect postoperative OF.

Conclusions
Postoperative OF significantly ameliorates over time in patients undergoing BNSRRP. The higher the postoperative EF score, the higher the OF throughout the FU time frame.
The influence of short-term variations in AM CVn systems on LISA measurements
Authors: Stroeer A. , Nelemans G. 
Published: September 2009

Abstract
We study the effect of short-term variations of the evolution of AM CVn systems on their gravitational wave (GW) emissions and in particular Laser Interferometer Space Antenna (LISA) observations. We model the systems according to their equilibrium mass-transfer evolution as driven by GW emission and tidal interaction, and determine their reaction to a sudden perturbation of the system. This is inspired by the suggestion to explain the orbital period evolution of the ultra-compact binary systems V407 Vul and RX−J0806+1527 by non-equilibrium mass transfer. The characteristics of the emitted GW signal are deduced from a Taylor expansion of a Newtonian quadrupolar emission model, and the changes in signal structure as visible to the LISA mission are determined. We show that short-term variations can significantly change the higher order terms in the expansion, and thus lead to spurious (non-) detection of frequency derivatives. This may hamper the estimation of the parameters of the system, in particular their masses and distances. However, we find that overall detection is still secured as signals still can be described by general templates. We conclude that a better modelling of the effects of short-term variations is needed to prepare the community for astrophysical evaluations of real GW data of AM CVn systems.
Teeth with double internal inflammatory resorption: Report of two cases
Authors: Rossi‐Fedele Giampiero , Figueiredo Jose A.P. , Abbott Paul V. 
Published: September 2009

AbstractInternal inflammatory resorption is an uncommon condition, which requires the presence of necrotic and infected pulp tissue within the coronal portion of the root canal system as well as inflamed pulp tissue apical to the resorptive defect. The defect usually appears as a bowl‐shaped radiolucency within the tooth root. Most cases are asymptomatic and many cases are only seen once the entire pulp has necrosed and all of the root canal system is infected resulting in apical periodontitis. The two cases presented are unusual in that they both had two distinct areas of internal inflammatory resorption. It is hypothesised that the more coronal lesion occurred first and then it ceased to continue resorbing the root in that position as the ‘necrotic, infected front’ moved apically at which time a second resorptive defect developed. The management, using different approaches, of these two cases of ‘double internal inflammatory resorption’ is described.
A Comparison of the Effect of Macerating Enzymes and Pulsed Electric Fields Technology on Phenolic Content and Color of Red Wine
Authors: Puértolas E. , Saldaña G. , Condón S. , Álvarez I. , Raso J. 
Published: September 2009

ABSTRACT:  The effect of the addition of 2 enzymatic preparations and the application of a pulsed electric fields treatment (PEF) on the phenolic content and color of Cabernet Sauvignon wine has been compared. The evolution of color intensity (CI), anthocyanic content (AC), and total polyphenol index (TPI) from crushing to 3 mo of aging in bottle was studied. The results demonstrated that both treatments promoted greater extraction of phenolic compounds, compared to the untreated wine. However, PEF technology was more effective. After 3 mo of storage, CI, AC, and TPI were 28%, 26%, and 11%, respectively, higher in PEF‐wine than in control wine. By contrast, while both enzymatic preparations increased the CI of the wine around 5%, only one of them increased the AC and TPI by 11% and 3%, respectively, in comparison with the control. After 3 mo of aging in bottle, the phenolic composition was also analyzed by high‐performance liquid chromatography (HPLC). The content of nonanthocyanic families was higher in PEF‐wine than in the rest of the wines. In wines treated by enzymes, only an increase in phenolic acids and flavonols with respect to the control was detected.Practical Application: Pulsed electric fields is a novel food processing technology that poses a very promising future to the enological field, due to its capacity to improve the mass transfer phenomenon. The continuous development of this technology allows nowadays the application of treatments at the semi‐industrial scale. In this article, it has been demonstrated that the application of a PEF treatment to the grape pomace before maceration/fermentation is more effective, in terms of color intensity and phenolic content, than the addition of macerating enzymes.
Effect of Fortification with Various Types of Milk Proteins on the Rheological Properties and Permeability of Nonfat Set Yogurt
Authors: Peng Y. , Serra M. , Horne D.S. , Lucey J.A. 
Published: September 2009

ABSTRACT:  Yogurt base was prepared from reconstituted skim milk powder (SMP) with 2.5% protein and fortified with additional 1% protein (wt/wt) from 4 different milk protein sources: SMP, milk protein isolate (MPI), micellar casein (MC), and sodium caseinate (NaCN). Heat‐treated yogurt mixes were fermented at 40 °C with a commercial yogurt culture until pH 4.6. During fermentation pH was monitored, and storage modulus (G′) and loss tangent (LT) were measured using dynamic oscillatory rheology. Yield stress (σyield) and permeability of gels were analyzed at pH 4.6. Addition of NaCN significantly reduced buffering capacity of yogurt mix by apparently solubilizing part of the indigenous colloidal calcium phosphate (CCP) in reconstituted SMP. Use of different types of milk protein did not affect pH development except for MC, which had the slowest fermentation due to its very high buffering. NaCN‐fortified yogurt had the highest G′ and σyield values at pH 4.6, as well as maximum LT values. Partial removal of CCP by NaCN before fermentation may have increased rearrangements in yogurt gel. Soluble casein molecules in NaCN‐fortified milks may have helped to increase G′ and LT values of yogurt gels by increasing the number of cross‐links between strands. Use of MC increased the CCP content but resulted in low G′ and σyield at pH 4.6, high LT and high permeability. The G′ value at pH 4.6 of yogurts increased in the order: SMP = MC < MPI < NaCN. Type of milk protein used to standardize the protein content had a significant impact on physical properties of yogurt.Practical Application: In yogurt processing, it is common to add additional milk solids to improve viscosity and textural attributes. There are many different types of milk protein powders that could potentially be used for fortification purposes. This study suggests that the type of milk protein used for fortification impacts yogurt properties and sodium caseinate gave the best textural results.
Dysglycemia Predicts Cardiovascular and Kidney Disease in the Kidney Early Evaluation Program
Authors: Whaley‐Connell Adam , Pavey Brian S. , McCullough Peter A. , Saab Georges , Li Suying , McFarlane Samy I. , Chen Shu‐Cheng , Vassalotti Joseph A. , Collins Allan J. , Bakris George , Sowers James R. ,   on behalf of the KEEP Investigators
Published: September 2009

J Clin Hypertens (Greenwich). 2010;12:51–58. ©2009 Wiley Periodicals, Inc.The cardiometabolic syndrome has been associated with both chronic kidney disease (CKD) and cardiovascular disease (CVD). Using data from the National Kidney Foundation‐Kidney Early Evaluation Program, the authors sought to investigate this association in a targeted CKD cohort. A total of 26,992 patients met eligibility criteria including age 18 years and older, diabetes, hypertension, or family history of CKD, diabetes, or hypertension and excluded those taking renal replacement therapy. Individuals were identified by Third Report of the National Cholesterol Education Program Adult Treatment Panel (NCEP‐ATP III) criteria (dysglycemia, hypertension, and dyslipidemia) and World Health Organization criteria (obesity and proteinuria). Univariate and multivariate analyses were used to evaluate increasing components of the cardiometabolic syndrome, CKD, and CVD. On multivariate analysis there was a graded relationship between increasing components with an increased prevalence of CKD and CVD. Additionally, there was a graded trend with the stage of dysglycemia (eg, normoglycemia, prediabetes, and overt diabetes) and increasing CKD. However, there was only an increased prevalence of CVD observed in the clinically diabetic group. This trend was also observed with increasing serum glucose levels and an increasing percent of CVD and CKD up to 160 mg/dL. However, prevalent CVD increased at >140 mg/dL and prevalent CKD at >180 mg/dL. Therefore, data support that increasing metabolic components and dysglycemia are strongly associated with an increased prevalence of CKD and CVD.