bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of retinol binding protein 4, visfatin, omentin-1 and vaspin in gout patients with various obesity phenotypes
Authors: Pavlova N. N. , Volgina E. V. , Medvedeva T. A. , Mishko N. Yu. 
Published: June 2024

Aim. To study the serum level of retinol-binding protein 4 (RBP4), visfatin, omentin-1 and vaspin in gout patients with different obesity phenotypes, as well as to assess the dynamics of studied parameters against the background of weight loss using an analog of glucagon-like peptide-1 (GLP-1) liraglutide.Material and methods. A total of 117 men with gout during the attack-free interval were examined. The patients were divided into 2 following groups: the 1st group consisted of 43 patients with a metabolically healthy obesity (MHO) and body mass index (BMI) ≥30 kg/m2; the second group consisted of 74 people with an metabolically unhealthy obesity (MUO) (carbohydrate metabolism disorders, hypertension (HTN) and BMI ≥30 kg/m2). The control group was represented by 38 respondents with a class 1 MHO. The blood concentrations of RBP4, omentin-1, visfatin, vaspin, serum uric acid, high-sensitivity C-reactive protein (hsCRP), HOMA-IR, anthropometric parameters were studied at the enrollment and 12 weeks later on the background of liraglutide therapy.Results. In gout patients with obesity, an increase in RBP4 and visfatin levels was revealed with a simultaneous decrease in omentin-1 and vaspin compared with patients in the control group and patients with gout with no metabolic disorders. The interrelationships of RBP4 and omentin-1 with the following metabolic syndrome components were established: BMI, increased triglycerides (TGs), increased total cholesterol, hsCRP, HOMA-IR and hyperinsulinemia, and reduced vaspin levels showed only a positive relationship with the HDL-C concentration (p<0,05). Visfatin positively correlates with diastolic blood pressure (r=0,29, p<0,01), the number of involved joints (r=0,577, p<0,01), the number of gout attacks (r=0,63, p<0,001).Conclusion. RBP4 and omentin-1 correlate with BMI and increased insulin sensitivity, whereas visfatin demonstrates an association with hyperuricemia and severity of gouty arthritis. Liraglutide therapy contributes to weight loss by 11,0±5,7%, improves the metabolic profile of patients with gout, increasing the content of omentin-1, lowering the RBP4 and uric acid serum concentration.
Metabolic health of the population: a modern view of the problem and solutions
Authors: Chumakova G. A. , Kuznetsova T. Yu. , Druzhilov M. A. , Gritsenko O. V. 
Published: June 2024

Studying the metabolic health of population around the world is becoming a priority area of modern medicine. This is associated with an increase in the prevalence of overweight and obesity, which leads to a significant increase in related metabolic diseases, which are actually complications of obesity, primarily visceral. According to 2019 data, overweight and obesity are associated with 5 million deaths and 160 million disability-adjusted life years, more than half of which are due to cardiovascular diseases. This challenge requires the development of cardiometabolic medicine and the training of new specialists.
Beneficial applications of herbal medicine in the problems associated with women health: A review
Authors: Upaganlawar Aman B. , Lohar Yogeshwari D. , Mahajan Manoj 
Published: June 2024

The social, economic and psychological facets of life are significantly impacted by health issues affecting women. Despite the widespread lack of understanding and health care systems, they are the lifeblood of all living things. In light of this, an effort has been undertaken to compile data on medicinal plants utilized in various women's health-related issues through literature reviews and field research. The findings showed that native plants are widely used worldwide as significant healing agents for women's health issues. Medicinal plants play a major role in women's healthcare in many rural places. For common disorders affecting women, such as urinary tract infections, pubertal changes, after-menopause syndrome, hot flashes, menopause, polycystic ovarian syndrome, vaginosis from bacteria, yeast-related infections, infertility, delayed labor, low breast milk production, abortion, and other female disorders, there are several medicinal and ayurvedic herbal remedies accessible. This article raises awareness of the issues facing women and the value of using medicinal herbs to heal them.
Comparative study of functional outcome in single plating and dual plating of unstable distal femur fractures
Authors: Vernekar Anish , DeMelo Waulden , Abdulla Ajmal , Salgaokar Nehal , Vargaonkar Gauresh 
Published: June 2024

Fractures of the distal femur remain challenging to treat as satisfactory outcome demands anatomical articular reduction, rigid and stable internal fixation along with early range of motion. The purpose of our study is to evaluate the functional outcome in patients with unstable fractures of the distal femur treated with single versus dual plating.: The study was a prospective study of 40 patients. The study was a prospective study of 40 patients (30 male and 10 female) with unstable fractures of the distal femur admitted to Goa medical college between June 2019 to June 2021 treated with open reduction and internal fixation of the distal femur with locked plates. After admission patients were subjected to routine pre operative evaluation and x-rays along with CT scan with 3 D reconstruction. During surgery, after lateral plating patients were subjected to varus stress test on table. If found to be positive, medial plate was applied. Medial plating was also advocated if medial cortex was found to be deficient due to severe communition or bone loss. Patients were followed up for an average of 10 months and knee function was evaluated evaluated using Sanders Functional Evaluation Knee Score. Out of the 40 patients treated with plating, 24 were treated with single lateral plate and 16 were treated with medial as well as lateral plate. Out of the 16 treated with dual plating, 2 were open fractures treated by staged procedure (lateral plating and subsequent medial plating with iliac crest bone graft via a separate medial incision after a period of 10 weeks following primary surgery). 3 of the patients treated with single lateral plate showed a varus collapse upon weight bearing 12 weeks post op. It was found that dual plating resulted in high union rates, early post op mobilisation due to more rigid fixation and less chances of varus collapse. However, overall when functional.
Assessment of functional outcome after ponseti method for congenital idiopathic clubfoot
Authors: Manivannan Sureshbabu , Thanikai Shenbaghavalli , Manickam E Lakshmikanth 
Published: June 2024

Congenital Talipes Equino Varus is a developmental deformation needing appropriate intervention for its correction, and the Ponseti technique is a conservative method used for its correction. This study aims to study the outcome of Ponseti correction using the Ponseti scoring system.Children entirely treated by the Ponseti method for idiopathic Clubfoot in a tertiary care hospital were studied from October 2016 to October 2018. Fifty-three children were recruited for the study. Ethical principles adhered to. Structured study proforma was administered after obtaining informed consent from the parent/guardian. Ponseti's scoring system was applied to study various outcomes. IBM SPSS version 22 was used for statistical analysis. Of 53 participants, 39 were male, and 14 were females. The mean total score in the study population was 82.36, with 30-98. Based on age at evaluation, the proportion of people with excellent outcomes was higher in the long-term group (30.76%), followed by the mid-term group (26.66%), and least in the short-term group (24%). Among the study participants, 24 (45.30%) had a Good (80-89) total score, 14 (26.4%) had an Excellent (90-100) total score, 9 (17%) had a Fair total score, and remaining 6 (11.3%) were had poor (&#60;70) total score.Conservative methods like the Ponseti technique can be utilized in our country as a treatment option for Clubfoot, with follow-up assessments using the Ponseti scoring system.
Extra-articular distal end radius fractures in elderly treated conservatively- functional outcome
Authors: Ranjolkar Rohit , Sajjanshetty Rajesh 
Published: June 2024

An ageing population is associated with an increase in the frequency of distal radius fractures, an orthopaedic problem that affects many people. Orthopaedic surgeons have special concerns while treating some types of fractures, including those involving the distal end of the radius that occur outside of the joint. For this reason, we set out to compare the efficacy of conventional cast methods with that of percutaneous pinning in a sample of older adults. From June 1, 2021 to June 1, 2022, researchers from Bidar Institute of Medical Sciences, Bidar, conducted a prospective, randomised trial. Thirty patients underwent cast immobilisation and closure reduction. thirty-one patients underwent closed reduction with percutaneous K wires. The patients underwent a clinical examination and X-rays at each subsequent follow-up. The results showed that the group that had closed reduction K-wire fixation had greater range of motion, VAS scores, and loss of radial length compared to the other group. When looking at the Saito chart and Lindstrom's criterion findings for both groups, it was also evident of this. In 13% of patients, a pin tract infection developed following K-wire fixation but went away after the wires were removed. This was the sole serious side effect of the procedure. When treating displaced, distal end radius fractures, the best, safest, and most complication-free method is closed reduction with percutaneous K-wire fixation.
Role of Bipolar hemiarthroplasty in geriatric patients with hip implant in failure
Authors: Kotresh Sharath Nandi , Katkar Minish Raghunath , Kumarjuvekar Saiel Anand , Mangwalkar Vishal Anand , Kakad Mohit Arun 
Published: June 2024

: The incidence of different hip implants failing in situ, irrespective of the cause, is on the rise. On the other side, its management remains widely understudied. Bipolar hemi-arthroplasty contributes to the salvage of failed trochanteric fracture fixation. Managing such cases necessitates skills related to complex trauma and advanced arthroplasty. It is crucial for the surgeon to comprehend and individualize surgical modalities based on the patient, fracture, and implant.This case series presents three different cases involving three distinct implants undergoing failure and their management through Bipolar Hemi-arthroplasty.: Three previously operated hip fracture cases with three different implants in the elderly population presented with implant in situ failure. They were surgically managed with a cemented modular bipolar prosthesis. Following this, a postoperative protocol was maintained, and the postoperative outcome was graded using the Hip scoring system. Bipolar arthroplasty enhances the long-term outcome of hemiarthroplasty due to reduced wear of the metal–cartilage interface. It stands as a viable, valid, and sound surgical modality compared to other surgical and non-surgical options.
Does 4 column classification of upper tibia fracture gives you better idea of fixation and impact on clinical outcome-analysis of 50 cases?
Authors: Shinde Abhishek Trymbak , Gadekar Girish Namdevrao , Fulwadwa Tanmay Rajkumar , Harchand Avinash Meharsingh 
Published: June 2024

The management of proximal tibia fracture has underdone significant changes in the recent years, while the main goals remain same i.e. to achieve a smooth articular surface, mechanical axis and joint stability. Recent advances in computed tomography and MRI based imaging have led to better understanding and classification of fracture and therefore better planning for treatment.This is a prospective analysis of the proximal tibia fracture managed as per 4 column 10 segment concept in view of functional outcomes. Radiological and functional outcomes using knee society score of the proximal tibia fractures operated and classified as per computed tomography based 4 column 10 segment concept were studied at 6 weeks, 3 months, 6 months and 9 months from year 2019 to 2022.Mean age of population sustaining proximal tibia fracture among males was 43.90 years and females was 48.71y with 86% predilection for male and 14% for female. Involvement of right tibia was 50 % in comparison to left tibia which was 46%, while 4% patients had involvement of both limbs. Distribution of proximal tibia fracture ; zero column -7.69%, one column- 55.77%, two column-21.15%, three column-15.38% average knee society score for proximal tibia fracture at the end of 9 months (knee score, function score) 87.65;79.54.Single incident of superficial infection was encountered managed with debridement and parenteral antibiotics. Single incident of surgical site infection managed with implant removal, debridement and parenteral antibiotics as per culture sensitivity. Single incident of common peroneal nerve palsy was encountered repaired with extended Lobenhoffer approach.Recent computed tomography based classification are very useful for fixation and deciding most suited surgical approach for proximal tibia fractures to achieve a smooth articular surface, mechanical axis and joint stability. Still, a long-term study with large study group is needed to confirm the usefulness of the same.
Trends in the Utilization of Outsourced Marketing Departments by Landlords of Boarding Rooms in Ho Chi Minh City
Authors: Dung Mai Thi , Nga Nguyen Ngoc Quynh 
Published: June 2024

In an era marked by escalating competition, the adoption of Outsourced Marketing practices emerges not only as a cost-saving measure but also as a catalyst for the enhancement of operational efficiency, and market competitiveness. The deployment of outsourced marketing strategies proves to be especially germane to the operational business of boarding-room enterprises in Ho Chi Minh City, rooted in features of operational scale, industry domain specificity, and responsiveness to evolving technological paradigms and consumer information acquisition demand. Fundamental advantages of outsourced marketing services to boarding room landlords encompass cost mitigation; revenue augmentation; simultaneously, increased time for specialized pursuits, brand equity amplification, and recognition level for the rental rooms system. This article principally discusses the trends in the utilization of outsourced marketing departments by boarding room landlords in Ho Chi Minh City, according to three focal domains: (1) The scale of outsourcing, (2) Process of managing and performing outsourced marketing, (3) The influence of outsourced marketing on the operational outcomes of boarding rooms enterprises.
Interactions between Parents and Children: The Impact of the COVID-19 Pandemic
Authors: Steinbach Marina , Vitali Kammer Pedro , Silva Camila Alvarenga da , Santos Kleyslla Souza , Lima Victor André Silva de , Massignan Carla , Bolan Michele da Silva 
Published: June 2024

This cross-sectional study aimed to assess the impact of the pandemic on parent-child interactions. Parents of 466 children between 3 and 10 years of age answered a questionnaire via WhatsApp and social media platforms, addressing the frequency of allowing the use of electronic devices, providing help with schoolwork, and whether children witnessed conflicts between their parents and between other adults. Independent variables included: age, gender, and education of both parents and children; family income; the number of income contributors that reside in the household; responsibility for domestic activities and if these chores affected their routine. Factors associated with changes in parent-child interactions were examined using multinomial regression models. An unadjusted analysis of the independent variables was carried out, with those having a p-value <0.20 included in the adjusted model. Odds ratios (OR) and 95% confidence intervals were obtained. Following the onset of the pandemic, parents provided more assistance with schoolwork (343 – 73.6%) and allowed electronic devices more frequently (358 – 76.8%), but the recurrence of arguing with one another (256 – 54.9%) remained unchanged. Significant changes in parent-child interactions occurred due to the pandemic.
INTERACTIVE LEARNING VIA DIGITAL STORYTELLING IN ELT AT ELEMENTARY SCHOOL : SYSTEMATIC REVIEW
Authors: Setyawati Vita Rahayu 
Published: June 2024

Abstract: In 4.0 era, digitalization in ELT at elementary school can be a complex learning tool. As we know that ICT facilitated and expanded access to education. One of the media using ICT in ELT is DS (Digital Storytelling). DS (Digital Storytelling) that is a story which narrate by using the digital multimedia such as: the video and the image. This study aims to analyse interactive learning via DS (Digital Storytelling) in ELT at elementary school. To understand kinds of the research studies that related to DS (Digital Storytelling), the writer used SLR (Systematic Literature Review) The research found through Google Scholar, Semantic Scholar, Pubmed, and Crossref from 2020-2023. This study executed in accordance 6 research articles consists of National Journal and International Journal. The result of this study showed that qualitative method research was the most popular research design. The result of this study that has been carried out that there are advantages applying DS (Digital Story telling) in interactive learning in ELT at the elementary school such as : it can improve the speaking skill, writing skill, reading skill, and listening skill, it can improve the students’ motivate and the students’ engagement, it can increase the levels of the students’ interactions and the students’ collaboration, it can improve the students’ collaboration, the students’ creativity skills, the students’ critical thinking. The innovation is needed to help teacher improve the quality of learning in elementary school. It promotes better understanding for the content and curricula for the educators. Keywords: Digital Storytelling, Interactive Learning, ELT, Elementary School
Studi Alkalisasi Serat Tandan Kosong Kelapa Sawit Sebagai Penguat Komposit Material Akustik.
Authors: Meilina Putri , Haryanti Ninis Hadi , Manik Tetti Novalina 
Published: June 2024

The use of empty oil palm fruit bunches as reinforcement in making composite boards has been carried out. Palm oil empty bunch fiber was obtained in the Kotabaru area, South Kalimantan. Palm oil empty fruit bunch fiber is hydrophilic which causes low adhesive properties between the fiber and the matrix so it is necessary to alkalize with 3% NaOH for 5 hours first. Alkalization has increased the cellulose content by 19.36% and reduced the lignin component by 9.04% and other components, such as hemicellulose, pectin, fat and others by 59.63%. Making composite boards uses the hand lay-up method and has succeeded in improving physical and mechanical properties. Water content according to SNI. The acoustic performance of composite boards shows significant results. The acoustic properties of composite boards without alkalization are sound absorbing, while with alkalization they are reflective. These results are supported by FTIR and SEM morphology results, which show that the interfacial bonding properties between the fiber and the matrix increase, thereby changing the acoustic performance of the TKKS composite board.Keywords: Alkalization, hand lay-up, acoustic performance, absorption, reflection.
ANALISA TERMAL PADA STERILIZER CRUDE PALM OIL DI PT. PERKEBUNAN NUSANTARA V SEI GALUH
Authors: Rafil Rafil Arizona , Liberti Martua Sinaga  , Shandy Kurniadi  , Eddy Elfiano  , Sehat Abdi Saragih  
Published: June 2024

Perebusan kelapa sawit khususnya pada Tandan Buah Segar (TBS) merupakan salah satu tahapan terpenting dalam proses pengolahan kelapa sawit. Selama proses perebusan diharapkan suhu da n tekanan uap serta waktu yang bekerja pada sterilizer harus tepat sehingga tidak merusak mutu CPO dan material sterilizer juga terjaga serta aman. Oleh karena itu dilakukanlah analisa termal pada sterilizer horizontal menggunakan pendekatan analisis termodinamika serta mencari efisiensi termal pada peak I, II dan III. Penelitian diselesaikan menggunakan metode analisis matematis. Pengumpulan data dilakukan menggunakan teknik studi literatur dan observasi lapangan. Hasil penelitian menunjukkan nilai transient conduction pada lori peak I: 392,476 MJ, peak II: 77,186 MJ, peak III: 28,457 MJ. Pada buah kelapa sawit, peak I: 2.164,273 MJ, peak II: 1.407,039 MJ, peak III: 480,314 MJ. pada peak I: 606,5398 MJ, peak II: 910,7164 MJ, peak III: 1.063,0479 MJ. Suhu akhir lori pada peak I: 384,5 K, peak II: 400,5 K, peak III: 406,42 K. Sedangkan buah kelapa sawit pada peak I: 350,20 K, peak II: 390,115 K, dan peak III: 406,268 K. Efisiensi sterilizer pada peak I: 81,081%, peak II: 80,6716%, pada peak III: 80,5332%.
PELAKSANAAN PROGRAM MAGANG DUNIA USAHA DAN INDUSTRI DITINJAU DARI PERSEPSI MAHASISWA PROGRAM STUDI PENDIDIKAN ADMINISTRASI PERKANTORAN FKIP UNS TAHUN 2019
Authors: Romdoni Muhammad , Sawiji Hery , Subarno Anton 
Published: June 2024

<p><em>This research aims to figure out: (1) the implementation of business and industrial internship program by the students of Office Administration Education of the year 2019, (2) the strategy implemented by the students of Office Administration Education in convincing partner institutions in the program implementation, and (3) the method used by the students of Office Administration Education to solve the inappropriate competencies on the task given in the implementation of the internship program.</em><em> This research using </em><em>qualitative method with narrative approach is applied in this research. Purposive sampling and snowball sampling method are used to select the research subjects and head of office administration education as a key informan The data collection techniques used are interview, observation, and document analysis. The result of the research shows that: 1) the implementation of the internship was in line with the guideline of Office Administration Internship 2017 so that it went smoothly; 2) The strategy implemented by the students in convincing the partner institutions was proposal. The proposals were created as attractive as possible and filled with elaborations of the skills offered by the students; and 3) The students solved the inappropriate competence during the internship period by (1) conducting consultation with the study program, (2) frequently asking questions, (3) asking help from other employees, and (4) studying independently.</em></p><p><strong><em> </em></strong></p><p align="center"> </p>