bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence, treatment efficacy, and risk factors of vascular complications in acute pancreatitis: A case–control study
Authors: Guo Xu , Tong Huan , Chen Liu Xiang , Wu Meng Juan , Liu Tian Qi , Mao Xiao Xiao , Xie Jia , Yang Feng , Zhou Die , Quan Xin , Qian Shuai Jie , Wei Bo , Wu Hao 
Published: June 2024

ObjectiveWe aimed to investigate the prevalence of vascular complications in acute pancreatitis (AP), to compare patient outcomes using various treatments, and to explore the related risk factors.MethodsConsecutive AP patients admitted from January 2010 to July 2017 were retrospectively included. Demographics, vascular complications, laboratory indices, and imaging findings were collected. Univariate and multivariate analyses were used to explore potential risk factors of vascular complications.ResultsOf 3048 AP patients, 808 (26.5%) had vascular complications, including visceral vein thrombosis, sinistral portal hypertension, and arterial complications. And 38 (4.7%) patients received anticoagulant therapy and had a higher rate of recanalization (P < 0.001). Bleeding occurred in 95 (11.8%) patients, who received further treatment. Multivariate analysis identified male gender (odds ratio [OR] 1.650, 95% confidence interval [CI] 1.101–2.472), hyperlipidemia (OR 1.714, 95% CI 1.356–2.165), disease recurrence (OR 3.727, 95% CI 2.713–5.118), smoking (OR 1.519, 95% CI 1.011–2.283), hemoglobin level (OR 0.987, 95% CI 0.981–0.993), white blood cell (WBC) count (OR 1.094, 95% CI 1.068–1.122), non‐vascular local complications (OR 3.018, 95% CI 1.992–4.573), computed tomography severity index (CTSI) (OR 1.425, 95% CI 1.273–1.596), and acute physiology and chronic health evaluation (APACHE) II score (OR 1.057, 95% CI 1.025–1.090) were related to vascular complications.ConclusionsVascular complications in AP is prevalent and their treatment is challenging. Further investigations are warranted to determine the optimal treatment strategy. Independent risk factors included male gender, hyperlipidemia, disease recurrence, smoking, WBC count, non‐vascular local complications, CTSI, and APACHE II score.
High‐cell‐density fed‐batch strategy to manufacture tailor‐made P(HB‐co‐HHx) by engineered Ralstonia eutropha at laboratory scale and pilot scale
Authors: Thiele Isabel , Santolin Lara , Detels Svea , Osele Riccardo , Neubauer Peter , Riedel Sebastian L. 
Published: June 2024

AbstractThe transition towards a sustainable bioeconomy requires the development of highly efficient bioprocesses that enable the production of bulk materials at a competitive price. This is particularly crucial for driving the commercialization of polyhydroxyalkanoates (PHAs) as biobased and biodegradable plastic substitutes. Among these, the copolymer poly(hydroxybutyrate‐co‐hydroxyhexanoate) (P(HB‐co‐HHx)) shows excellent material properties that can be tuned by regulating its monomer composition. In this study, we developed a high‐cell‐density fed‐batch strategy using mixtures of fructose and canola oil to modulate the molar composition of P(HB‐co‐HHx) produced by Ralstonia eutropha Re2058/pCB113 at 1‐L laboratory scale up to 150‐L pilot scale. With cell densities >100 g L−1 containing 70–80 wt% of PHA with tunable HHx contents in the range of 9.0–14.6 mol% and productivities of up to 1.5 g L−1 h−1, we demonstrate the tailor‐made production of P(HB‐co‐HHx) at an industrially relevant scale. Ultimately, this strategy enables the production of PHA bioplastics with defined material properties on the kilogram scale, which is often required for testing and adapting manufacturing processes to target diverse applications.
SLRfinder: A method to detect candidate sex‐linked regions with linkage disequilibrium clustering
Authors: Yi Xueling , Kemppainen Petri , Merilä Juha 
Published: June 2024

AbstractDespite their critical roles in genetic sex determination, sex chromosomes remain unknown in many non‐model organisms, especially those having recently evolved sex‐linked regions (SLRs). These evolutionarily young and labile sex chromosomes are important for understanding early sex chromosome evolution but are difficult to identify due to the lack of Y/W degeneration and SLRs limited to small genomic regions. Here, we present SLRfinder, a method to identify candidate SLRs using linkage disequilibrium (LD) clustering, heterozygosity and genetic divergence. SLRfinder does not rely on specific sequencing methods or a specific type of reference genome (e.g., from the homomorphic sex). In addition, the input of SLRfinder does not require phenotypic sexes, which may be unknown from population sampling, but sex information can be incorporated and is necessary to validate candidate SLRs. We tested SLRfinder using various published datasets and compared it to the local principal component analysis (PCA) method and the depth‐based method Sex Assignment Through Coverage (SATC). As expected, the local PCA method could not be used to identify unknown SLRs. SATC works better on conserved sex chromosomes, whereas SLRfinder outperforms SATC in analysing labile sex chromosomes, especially when SLRs harbour inversions. Power analyses showed that SLRfinder worked better when sampling more populations that share the same SLR. If analysing one population, a relatively larger sample size (around 50) is needed for sufficient statistical power to detect significant SLR candidates, although true SLRs are likely always top‐ranked. SLRfinder provides a novel and complementary approach for identifying SLRs and uncovering additional sex chromosome diversity in nature.
Can second‐chance provisions increase the effectiveness of penalty contracts? Evidence from a quasi field experiment
Authors: Chen Clara Xiaoling , Wang Laura W. , Wu Anne , Wu Steve Yuching 
Published: June 2024

AbstractPenalty contracts are commonly utilized in developing countries. Such contracts may be perceived as unfair, potentially reducing employee motivation and performance. We predict that adding a second‐chance provision, an opportunity to reverse a penalty for poor performance if subsequent performance improves, could improve the effectiveness of penalty contracts. In a quasi field experiment at a company with two manufacturing facilities in Taiwan, we treated one facility with a traditional‐penalty contract without a second‐chance provision and the other with a penalty contract with a second‐chance provision. We observe a significant difference in the two treatment effects, with employee performance decreasing significantly after the traditional‐penalty treatment but showing no decrease when a second‐chance provision was included. Further analysis reveals that this difference is mediated by employees' fairness perceptions. These results provide valuable insights to governments, nongovernmental organizations, and multinationals as they work together to improve the fairness of global compensation practices.
Do patients with osteoarthritis lose weight prior to elective joint replacement?
Authors: Wall Christopher J. , Lee Susie S. , Ma Yanru , de Steiger Richard N. , Vertullo Christopher J. , Kondalsamy‐Chennakesavan Srinivas 
Published: June 2024

AbstractBackgroundObesity is a known risk factor for the development of osteoarthritis and the subsequent need for joint replacement. Weight loss has been shown to reduce pain, disability, and the need for joint replacement, particularly in patients with knee osteoarthritis. The aim of this study was to investigate pre‐operative weight change in patients with hip, knee, and shoulder osteoarthritis at a regional, public hospital in Australia, to identify opportunities for pre‐operative weight‐loss intervention.MethodsA retrospective review of patients who underwent elective primary total hip (THR), knee (TKR), and shoulder (TSR) replacement for osteoarthritis was conducted between December 2019 and December 2022. BMI data were collected at three time points: (1) general practitioner (GP) referral; (2) orthopaedic clinic review; and (3) pre‐admission clinic (PAC) assessment.ResultsA total of 496 patients were included in the study, of which 205 underwent THR, 251 underwent TKR, and 40 underwent TSR. The mean patient age was 67 years, and 46.4% were female. At the time of GP referral, the mean body mass index (BMI) was 31.4 kg/m2. Across the study period, only 2% of patients experienced clinically significant weight loss pre‐operatively (≥5% of total body weight).ConclusionThis study has demonstrated that very few patients lose weight prior to undergoing joint replacement in the public sector in Australia. This highlights the need for targeted non‐surgical weight loss interventions for patients currently awaiting joint replacement.
Exploring stakeholder engagement network behavior: Strategic and managerial implications for corporate social responsibility
Authors: Linzalone Roberto , Ammirato Salvatore , Felicetti Alberto Michele , Corvello Vincenzo , Santarsiero Francesco 
Published: June 2024

AbstractThis paper investigates the relationship between Stakeholder Engagement (SE) and Corporate Social Responsibility (CSR), approaching CSR as a complex system made up of components and interactions. Adopting a System Thinking approach to analyze CSR in a stakeholders‐company network, explorative research is conducted through three stages: (1) a critical literature review aimed to identify the components of the CSR system model, (2) the development of the dataset and of the Causal Loop Diagram (CLD) model, (3) the analysis of the CSR behavior in light of the ‘system archetypes’ underpinning the system. The analysis reveals both the structure and the dynamics of CSR and explain its behavior in light of the stakeholder engagement network variables. Findings from this research underscore the existence of six feedback loops, which characterize the relation CSR‐SE. The ‘company‐stakeholder fit’ acts as a growth engine for the stakeholder engagement network, however other balancing dynamics (e.g., detriment of business objectives) require a tradeoff between Social and Business orientation. This paper contributes to a more profound understanding of the relation between CSR and stakeholder engagement, showing in particular the link between CSR and SE under the assumption of stakeholder‐company network. The insights provided serve as a guide for managers and policymakers to navigate the complex dynamics of SE to inform effective strategies of CSR based on network structural actions.
Can corporate social responsibility reduce customer mistreatment? A contingent dual‐process model
Authors: Zhan Xiaojun , Lu Na , Lin Weipeng , Luo Wenhao , Zhang Xixia 
Published: June 2024

AbstractAlthough corporate social responsibility (CSR) has been widely studied, little is known about whether it has implications for customer mistreatment. In this study, we aim to understand how and when CSR is related to customer incivility, a typical type of mistreatment in service contexts. Integrating the perspectives of social exchange theory and social identity theory, we theorize that CSR influences customer incivility via customer trust and customer identification, which are contingent on front‐line employees' emotional labor (i.e., surface acting and deep acting) during service interactions. In our two‐source field study involving 332 employee–customer dyads, CSR promoted both customer trust and customer identification, which in turn reduced customer incivility. Moreover, the indirect relationship between CSR and customer incivility via customer trust (but not customer identification) was weakened by employee surface acting but strengthened by employee deep acting. Taken together, this study uncovers the relationship between CSR and customer mistreatment by exploring how and when CSR influences customer incivility, which advances the understanding of the customer‐related implications of CSR.
Boredom due to being over‐ or under‐challenged in mathematics: A latent profile analysis
Authors: Schwartze Manuel M. , Frenzel Anne C. , Goetz Thomas , Lohbeck Annette , Bednorz David , Kleine Michael , Pekrun Reinhard 
Published: June 2024

AbstractBackgroundRecent research on boredom suggests that it can emerge in situations characterized by over‐ and under‐challenge. In learning contexts, this implies that high boredom may be experienced both by low‐ and high‐achieving students.AimsThis research aimed to explore the existence and prevalence of boredom due to being over‐ and under‐challenged in mathematics, for which empirical evidence is lacking.SampleWe employed a sample of 1.407 students (fifth to ninth graders) from all three secondary school tracks (lower, middle and upper) in Bavaria (Germany).MethodsBoredom was assessed via self‐report and achievement via a standardized mathematics test. We used latent profile analysis to identify groups characterized by different levels of boredom and achievement, and we additionally examined gender and school track as group membership predictors.ResultsResults revealed four distinct groups, of which two showed considerably high boredom. One was coupled with low achievement on the test (i.e. ‘over‐challenged group’, 13% of the total sample), and one was coupled with high achievement (i.e. ‘under‐challenged group’, 21%). Furthermore, we found a low boredom and high achievement (i.e. ‘well‐off group’, 27%) and a relatively low boredom low achievement group (i.e. ‘indifferent group’, 39%). Girls were overrepresented in the over‐challenged group, and students from the upper school track were underrepresented in the under‐challenged group.ConclusionOur research emphasizes the need to openly discuss and further investigate boredom due to being over‐ and under‐challenged.
Teaching expectancy improves video‐based learning: Evidence from eye‐movement synchronization
Authors: Liang Zheng , Ga Riman , Bai Han , Zhao Qingbai , Wang Guixian , Lai Qing , Chen Shi , Yu Quanlei , Zhou Zhijin 
Published: June 2024

AbstractVideo‐based learning (VBL) is popular, yet students tend to learn video material passively. Instilling teaching expectancy is a strategy to promote active processing by learners, but it is unclear how effective it will be in improving VBL. This study examined the role of teaching expectancy on VBL by comparing the learning outcomes and metacognitive monitoring of 94 learners with different expectancies (teaching, test or no expectancy). Results showed that the teaching expectancy group had better learning outcomes and no significant difference in the metacognitive monitoring of three groups. We further explored the visual behaviour patterns of learners with different expectancies by using the indicator of eye‐movement synchronization. It was found that synchronization was significantly lower in both the teaching and test expectancy groups than in the no expectancy group, and the test expectancy group was significantly lower than the teaching expectancy group. This result suggests that both teaching and test expectancy enhance the active processing of VBL. However, by sliding window analysis, we found that the teaching expectancy group used a flexible and planned attention allocation. Our findings confirmed the effectiveness of teaching expectancy in VBL. Also, this study provided evidence for the applicability of eye‐tracking techniques to assess VBL.
Practitioner notesWhat is already known about this topic

Video‐based learning has become a popular way, yet students tend to learn video material passively.
When students learn with teaching expectancy, they are more likely to engage in deep processing, which has been proven in static multimedia learning.
Individuals show high eye‐movement synchronization when watching the same video, and this synchronization may be reduced when they engage in top‐down processing.
What this paper adds

Teaching expectancy improves learning performance in Video‐based learning.
Teaching expectancy enhances active cognitive processing in Video‐based learning.
During the video viewing, learners with teaching expectancy not only followed the instructor's explanations but also engaged in active top‐down processing, demonstrating flexible and planned attention allocation.
Implications for practice and/or policy

Utilizing teaching as an intention can serve as an effective learning strategy for Video‐based learning.
The use of eye‐movement intersubject correlation to analyse visual behaviour patterns provides a new way to explore how people learn from dynamic multimedia materials.
Mutual communication intervention for colorectal cancer patient–spousal caregiver dyads: A randomized controlled trial
Authors: Zhou Junrui , Wang Zhiming , Chen Xuan , Lin Chunyan , Zhao Jie , Loke Alice Yuen , Li Qiuping 
Published: June 2024

AbstractObjectiveGender could impact the psychosocial outcomes and coping strategies of cancer patients and their spousal caregivers (SCs). This study aims to develop a gender‐concerned program for colorectal cancer (CRC) couple‐based mutual communication intervention (MCI) and to assess its effectiveness on the intra‐couple relationship and the individual functions of the partners.DesignA randomized clinical trial with two study groups was utilized.MethodsA total of 144 CRC patients and their SCs were randomly assigned to either MCI or usual care (UC) groups, and all of them were required to complete the measurements at baseline and post‐intervention. The primary outcome was for mutual communication, and the secondary outcomes included dyadic coping, relationship satisfaction, anxiety, depression, benefit finding and quality of life. The data were analysed by multi‐level modelling.ResultsThe MCI program was feasible and acceptable for Chinese CRC couples and was effective for the improvement of the intra‐couple relationship and the individual functions of each partner. CRC patients showed more improvement in mutual communication and dyadic coping than their SCs in the MCI group. Also, this intervention effectiveness was found to be independent of gender.ConclusionsThe MCI program is beneficial for Chinese CRC couple's adaptation outcomes. This suggests that clinical medical staff should consider the gender tendency during the implementation of interventions. More researches are needed to extend the application of the MCI program to different participants (e.g. patients with the diagnosis of other types of cancer and their SCs).
How Effective Are Ireland's Monitory Mechanisms in Improving Its Child Protection and Welfare Services?
Authors: Burns Kenneth , Boyle Eva , Geary Susan , King Emma 
Published: June 2024

ABSTRACTChild protection and welfare systems are entrusted with significant power by governments and are therefore a significant focus of monitoring activities. Monitoring can help to build a better child protection system and to ensure child safety; track policy and legislative implementation and resource allocation; contribute to preventing systemic ‘failures’; provide data for system, policy, and legislative reforms; and support continuous improvement. The Irish system is worth examining for three reasons. First, Ireland has had a single state‐provided child protection and welfare service called the Child and Family Agency. Second, the system has been through a sustained period of development. Third, Ireland has one dedicated statutory authority called the Health Information and Quality Authority (HIQA). This article provides a case study of the strategies and mechanisms adopted by Ireland to monitor the operation, quality and development of its child protection and welfare system. We will show that there is significant direct and indirect monitoring and focus on child protection from regulators, civil society organisations, government agencies and committees and independent actors. Such monitoring has significantly influenced the development of policy, practice and the development of the child protection system in Ireland.
RouteVis: Quantitative Visual Analytics of Various Factors to Understand Route Choice Preferences
Authors: Lv C. , Zhang H. , Lin Y. , Dong J. , Tian L. 
Published: June 2024

AbstractAnalyzing the preference of route choice not only facilitates the understanding of individuals' decision‐making behavior, but also provides valuable information for improving traffic management strategies. As the layout of the road network, the variability of individual preferences and the spatial distribution of origins and destinations all play a role in route choice, it is a great challenge to reveal the interplay of such numerous complex factors. In this paper, we propose RouteVis, an interactive visual analytics system that enables traffic analysts to gain insight into what factors drive individuals to choose a specific route. To uncover the relationship between route choice and influencing factors, we design a quantitative analytical framework that supports analysts in conducting closed‐loop analysis of various factors, i.e., data preprocessing, route identification, and the quantification of influence and contribution. Furthermore, given the multidimensional and spatio‐temporal characteristics of the analysis results, we customize a set of coordinated views and visual designs to provide an intuitive presentation of the factors affecting people's travels, thus freeing analysts from tedious repetitive tasks and significantly enhancing work efficiency. Two typical usage scenarios and expert feedback on the system's functionality demonstrate that RouteVis can greatly enhance the capabilities of understanding the travel status.
Persist: Persistent and Reusable Interactions in Computational Notebooks
Authors: Gadhave K. , Cutler Z. , Lex A. 
Published: June 2024

AbstractComputational notebooks, such as Jupyter, support rich data visualization. However, even when visualizations in notebooks are interactive, they are a dead end: Interactive data manipulations, such as selections, applying labels, filters, categorizations, or fixes to column or cell values, could be efficiently applied in interactive visual components, but interactive components typically cannot manipulate Python data structures. Furthermore, actions performed in interactive plots are lost as soon as the cell is re‐run, prohibiting reusability and reproducibility. To remedy this problem, we introduce Persist, a family of techniques to (a) capture interaction provenance, enabling the persistence of interactions, and (b) map interactions to data manipulations that can be applied to dataframes. We implement our approach as a JupyterLab extension that supports tracking interactions in Vega‐Altair plots and in a data table view. Persist can re‐execute interaction provenance when a notebook or a cell is re‐executed, enabling reproducibility and re‐use. We evaluate Persist in a user study targeting data manipulations with 11 participants skilled in Python and Pandas, comparing it to traditional code‐based approaches. Participants were consistently faster and were able to correctly complete more tasks with Persist.