bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Cell Cycle Kinetics Using Flow Cytometry from Paraffin‐Embedded Tissues in Endometrial Adenocarcinoma
Authors: Takahashi Yoshiki , Matsumoto Hisanori , Wakuda Koji , Ishiguro Tatsuya , Yoshida Yoshinobu 
Published: August 2010

AbstractFlow cytometric analysis of cell cycle kinetics from paraffin‐embedded tissues was performed to evaluate the DNA heterogeneity and risk factor of endometrial adenocarcinoma. We studied 54 tumor samples and 6 controls with normal endometrium, and all samples were measured for S‐phase fraction (SPF) and proliferative index (PI). Intratumor variations of SPF and PI values were evaluated at 3 different sites of the tumor; (1) primary endometrial lesion, (2) the site of myometrial invasion, and (3) metastatic lesions. SPF and PI values of endometrial adenocarcinoma were significantly higher than those of normal endometrium. There was a significant correlation between the PI value and the histological grade. SPF and PI values at the primary endometrial lesion had a significant correlation with the prognosis of this cancer at stage III or IV. SPF and PI values which were measured at the site of myometrial invasion tended to be lower than those from other sites. Our results indicate that the SPF and PI values of endometrial lesions are one of the important prognostic factors of endometrial adenocarcinoma at stage III or IV. In addition, DNA syntheses of endometrial adenocarcinoma cells display intratumor heterogeneity.
Camp Laparoscopic Sterilization Deaths in Gujarat State, India, 1978–1980
Authors: Bhatt Rohit V. 
Published: August 2010

AbstractAn early experience of camp laparoscopic sterilization in Gujarat State, India, resulted in 22 deaths among 106,500 women undergoing the operation during 1979 and 1980. Increased risk of death was seen when larger numbers of procedures were performed by year or month of year. The least experienced surgeons had the highest case‐fatality rate. Improvised settings (i.e., school buildings) exacerbated the risk of death, as did advanced age, and, to a lesser extent, high parity. Errors in clinical judgment were identified in some fatal procedures. A system of health audit of large sterilization programs is needed.
Urodynamic Investigation in the Management of Incontinent Women
Authors: Umstad Mark P. , Glenning Peter P. 
Published: August 2010

AbstractOne hundred and sixty‐eight women presenting to a Urinary Incontinence Clinic were studied. Only 52% had a urodynamic diagnosis that supported their clinical signs and symptoms. The response rates to various modalities of treatment for each urinary disorder are described. Fifty‐one percent achieved a complete response with the treatment selected, 27% had a partial response, and 10% did not respond or deteriorated. Twelve percent of patients were lost to follow‐up.
Intra‐Cervical Prostaglandin E2 Gel in Management of Dead Fetus in utero
Authors: Herabutya Yongyoth , O‐Prasertsawat Pratak 
Published: August 2010

AbstractDuring a two and a half year period at this institution, prostaglandin E2 gel was administrated intra‐cervically in the treatment of 74 cases of dead fetus in utero. Delivery was achieved in all 74 cases. The mean interval from induction to delivery of the fetus was 17.6 hours with a mean total dosage used of 5.2 mg. Seventy percent of the patients spontaneously expelled the fetus and placenta completely. Gastrointestinal side‐effects were minimal with no medication needed. Oxytocin was used in 17 (23%) patients mainly to expedite the expulsion of the fetus. Intra‐cervical administration appeared to result in fewer side‐effects and was more cost effective than vaginal prostaglandin therapy for the treatment of dead fetus.
Changes in Plasma Levels of Lipid Peroxide and Vitamin E during Pregnancy
Authors: Iioka Hideaki , Akada Shinobu , Hisanaga Hiroyasu , Shimamoto Takako , Yamada Yoshihiko , Moriyama Ikuko S. , Ichijo Motohiko 
Published: August 2010

AbstractThe present study was undertaken in order to determine the changes in blood levels of lipid peroxide and vitamin E during pregnancy. 1. The man plasma level of lipid peroxide was 0.89±0.13 nmole/ml for non‐pregnant women, while in pregnant women it was increased as the progressed pregnancy reaching 2.71±0.29 nmole/ml at full term. 2. The mean plasma, red cell and platelet levels of vitamin E were 6.6±0.9 μg/ml, 3.55±0.38 μg/ml packed cell and 99±25 μg/ml protein for non‐pregnant women, while in pregnant women the levels changed as the progressed pregnancy becoming 15.5±0.9 μg/ml, 2.43±0.24 μg/ml packed cell, and 244±19 μg/g protein at full term.It was shown in this study that during pregnancy the plasma level of lipid peroxide increased while the levels of vitamin E which inhibited the formation of lipid peroxide, increased in plasma and platelets, but decreased in red cells.
Serial Changes of Serum CA125 Levels during Menstrual Cycles
Authors: Nonogaki Hirofumi , Fujii Shingo , Konishi Ikuo , Nanbu Yoshihiko , Kobayashi Fuminori , Mori Takahide 
Published: August 2010

AbstractSerial changes of serum CA125 levels during 32 menstrual cycles were examined in 32 healthy young women (19–21 years of age) charting basal body temperature (BBT) and measuring serum estradiol and progesterone levels. Analysis of BBT charts and serum progesterone levels revealed that the 32 menstrual cycles could be classified into either an ovulatory cycle with a sustained BBT temperature increase for at least 10 days (type I: 9 cycles), an ovulatory cycle with a sustained BBT temperature increase for less than 10 days (type II: 17 cycles), or anovulation (type III: 6 cycles). All 32 cycles exhibited basal CA125 levels of less than 35 u/ml throughout the cycle, except during the period of menstruation. At menstruation, 7 of the 9 cycles of type I showed a marked, transient elevation of CA125 levels from previous basal levels (a mean net increase). On the other hand, 12 of 17 cycles of type II showed only a slight elevation of CA125 levels during the period of menstruation. None of the 6 cycles of type III showed any apparent increase in CA125 levels during the period of menstruation. The mean net increase of CA125 levels during the period of menstruation in the cycles of type I was significantly higher than that of the cycles of type II (p<0.05) and type III (p<0.05). These results imply that a transient elevation of serum CA125 levels during the period of menstruation occurs in cycles with ovulation, and the levels of elevation seem to be closely associated with the duration of the sustained BBT temperature increase.
Ectopic Ovary in the Omentum
Authors: Peedicayil Abraham , Sarada Venkateswaran , Jairaj Prabha , Chandi Sushil M. 
Published: August 2010

AbstractAt caesarean section the right ovary of a patient was found to be absent. There was an omental cyst that was excised and this was found to be an ectopic ovary. This case is reported because of its rarity. The nomenclature and embryological aspects of the condition are discussed.
Government‐Funding Program on Reversal of Tubal Sterilization
Authors: Bai Byoung Choo , Park Chan Moo , Kwak Hyun Mo , Whang Young Whan 
Published: August 2010

AbstractThree hundred and sixty‐one women were provided government‐funded sterilization reversal services with the technique of microsurgery. A large majority of reasons (89.8%) for requesting reversal surgery was a loss of children, and the mean interval between sterilization and reversal was 28.7 months. Two hundred and seven (69.7%) of 297 follow‐up cases have experienced term delivery or intra‐uterine pregnancy and 5 cases were ectopic pregnancy. The largest number of reversal clients (63.3%) were sterilized by the laparoscopic unipolar coagulation technique and the next largest group (24.2%) was sterilized by the laparoscopic banding technique. The highest pregnancy rate (77.8%) was shown in clients who had undergone laparoscopic banding technique while the lowest (65.9%) was the group of laparoscopic unipolar coagulation. A more than 60% of the clients became pregnant within 6 months of their reversal surgery, with the shortest interval being 1 month, the longest 39 months, and the mean 7.6 months. A large majority of the successful cases, 81.6%, were pregnant within 1 year of their reversal surgery.
Origin of Macrophage Colony‐Stimulating Factor (M‐CSF) and Granulocyte Colony‐Stimulating Factor (G‐CSF) in Amniotic Fluid
Authors: Saito Mami , Saito Shigeru , Nakagawa Tomoyoshi , Ichijo Motohiko , Motoyoshi Kazuo 
Published: August 2010

AbstractA large amount of M‐CSF and G‐CSF exists in human amniotic fluid and both are considered to have some physiological affect on maintaining pregnancy. We therefore examined the source of M‐CSF and G‐CSF found in the amniotic fluid.The average level of M‐CSF in the amniotic fluid of patients without complications was 17.3±8.5 ng/ml and that of G‐CSF 1.85±1.72 ng/ml, both being high values. In neonatal urine, the average level of M‐CSF was also very high, 144.3 ±97.0 ng/ml, but that of G‐CSF was below the determination limit of 60 pg/ml.Immunohistochemical staining indicated that production of M‐CSF and G‐CSF was localized in the epithelial cells of fetal membrane.On the basis of the above observations, M‐CSF was found to derive from neonatal urine and the epithelial cells of fetal membrane, and G‐CSF from the epithelial cells of fetal membrane.
A Sero‐Epidemiological Study on Mother‐to‐Child Transmission of HTLV‐I in Southern Kyushu, Japan*
Authors: Oki Toshitaka , Yoshinaga Mitsuhiro , Otsuka Hirofumi , Miyata Koichiro , Sonoda Shunrdu , Nagata Yukihiro 
Published: August 2010

AbstractIn vertical transmission of HTLV‐I the duration of breast‐feeding seems to be an important risk factor. In this study, we made prospective and retrospective surveys on the rate of vertical transmission of HTLV‐I in infants and their siblings born to HTLV‐I seropositive mothers. The results obtained were as follows.

In the prospective study, 885 of the 16,283 pregnant women examined were HTLV‐I seropositive, and the seropositive rate was 5.4%. The seroconversion rates of short‐term (>7 months) and long‐term (≥7 months) breast‐feeders were 3.8% (1/ 26 cases) and 25.0% (1/4 cases) respectively, and the rate of bottle‐feeders was 5.6% (10/177 cases). Short‐term breast‐feeding tended to yield a lower seroconversion rate of infants. In addition, the seroconversion rate of short‐term breast‐feeders was nearly equal to that of bottle‐feeders: 3.8% vs. 5.6%.
In the retrospective study, the seroconversion rates of short‐term and long‐term breast‐feeders in their siblings were 4.5% (3/67 cases) and 14.0% (19/136 cases) respectively. There was a significant difference between the 2 groups (P<0.01).

Thus, the results of our retrospective and prospective studies suggest that short‐term breast‐feeding might lessen the risk of breast‐milk‐borne transmission of HTLV‐I from carrier mothers to their children.
Heterophile Antigens in Serous Cystadenocarcinoma of the Human Ovary
Authors: Kamada Masaharu , Mori Tsuneatsu , Sakamoto Yasuki , Daitoh Toshifumi , Furumoto Hiroyuki , Irahara Minoru , Aono Toshihiro , Mori Takahide 
Published: August 2010

AbstractAs the aberrance of carbohydrate moieties, the appearance of heterophile antigens in human ovarian cancer tissue was studied using various heterophile antigens and antibodies together with antisera raised in rabbits by immunization with extracts of human ovarian cancer tissues. In the immunodiffusion test, rabbit antisera reacted with a heat‐stable, perchloric‐acid extractable antigen that was different from CEA and CA125 and possessed Hanganutziu‐Deicher (HD)‐type specificity in all 4 specimens of serous cystadenocarcinoma of the ovary. Furthermore, a pathologic serum with strong HD‐antibody complex formed a precipitin line with one of them. In the cancer tissue, we also immunochemically demonstrated the presence of rat‐erythrocyte antigens. However, other types of heterophile antigens, such as Paul‐Bunnell and Forssman, were not detected. These results suggest that HD‐type antigens appear in serous cystadenocarcinoma of the human ovary, one in broad distribution and some in specific cases.
Sonographic Prenatal Diagnosis of Congenital Heart Defects in Thoraco‐Omphalopagus
Authors: Sukcharoen Nares , Wannakrairot Pongsak 
Published: August 2010

AbstractThoraco‐omphalopagus is the most common variety of conjoined twins. About 90% of the conjoined thoraco‐omphalopagus twins have a common pericardium, and 75% have conjoined hearts. Options for the treatment of thoraco‐omphalopagus are largely dependent on the anatomy of the cardiovascular system. The extent of the conjunction of the heart and the severity of the associated cardiac defects primarily determine the feasibility of successful separation of the infants. Two‐dimensional echocardio‐graphy and color Doppler examination has become the method used to investigate cardiovascular system of conjoined twins with a high degree of confidence. A case of thoraco‐omphalopagus conjoined twins prenatally determined of the extent of cardiac conjunction and diagnosis of associated defects by these methods is presented.
A Case Report on Surgically Managed Elephantoid Vulva Due to Donovanosis
Authors: Suneja Amita , Chaudhry Rama , Ramam M. , Agarwal N. , Talwar V. 
Published: August 2010

AbstractAn unusual case of vulval donovanosis is reported from non endemic part of India, who presented with huge ulcerovegetative growth on the vulva and ultimately required surgical resection in addition to long term therapy with antibiotics.
Changes of Hemorheologic Properties during Normal Human Pregnancy
Authors: Eguchi Katsuto , Mitsui Yukiteru , Yonezawa Masaru , Oguni Nobutsugu , Hiramatsu Yuji 
Published: August 2010

AbstractTo investigate alterations of hemorheologic properties during pregnancy, we measured the hematocrit (Hct) and fibrinogen levels, blood viscosity, and erythrocyte de‐formability in 10 healthy nonpregnant women and in 10 women with uncomplicated pregnancies.The Hct decreased during pregnancy, while the plasma fibrinogen concentration was elevated. No significant changes in blood viscosity were observed throughout pregnancy. Erythrocyte deformability was significantly decreased in pregnancy when compared to the nonpregnant state, but returned to the nonpregnant level by the 7th postpartum day.These findings suggest that adequate microcirculation is maintained in the uter‐oplacental unit during gestation by hemodilution, which prevents an elevation of blood viscosity despite the increase in fibrinogen and the decrease of erythrocyte deformability. These changes are thus thought to be among the physiological maternal adaptations to fetal growth and development.
Qualificated Discrimination of Ovarian Malignancy by Diagnostic Ultrasound
Authors: Hirai Takeshi , Akamatsu Nobuo , Sekiba Kaoru , Tsubota Nobutaka , Tsuru Satoko 
Published: August 2010

AbstractUltrasonograms of 214 ovarian masses in 184 patients were studied to discriminate ovarian malignancies from benign masses and to help in developing a new scoring system using ultrasonographic findings with weight‐adjusted scores.The 76 masses that showed cystic patterns only were directly determined to be benign, having an expected success rate of 97.4%. The remaining 138 masses, of which 116 showed mixed patterns and 22 of which showed solid patterns, were analyzed by the Quantification method No. 2 of Hayashi to select the effective ultrasonic findings and to obtain a good discriminant function. Eleven findings (items) expressing 29 categories were selected, and a discriminant function composed with a weight‐adjusted score for each category was obtained as the result of the analysis. Using these functions, the 86.6% of the ovarian masses with mixed or solid patterns were correctly discriminated as being malignant, borderline‐malignant, or benign. According to internal checks of all ovarian masses, the success rate was 90.2%. Then 73 ovarian masses of 65 new patients were discriminated as the external check, and a success rate of 93.2% was obtained.It is concluded that this newly developed scoring system using ultrasonic findings is useful in discriminating ovarian malignancies from benign ones.
Color and Pulsed Doppler Ultrasonography of Reversed Umbilical Blood Flow in an Acardiac Twin
Authors: Ishimatsu Junji , Nakanami Hiromi , Hamada Teiji , Yakushiji Michiaki 
Published: August 2010

AbstractPrenatal diagnosis of an acardiac twin pregnancy was performed. At 30 gestational weeks, pulsed color Doppler ultrasound revealed polyhydramnios, reversed‐pulsatile blood flow in the umbilical artery and vein of the acardiac twin, and artery‐artery anastomosis on the placental surface. The total cardiac dimension, maximum blood flow velocity of the ascending aorta and the pulmonary artery in the alive twin were in the normal range.
Prediction of Dystocia by Entanglement (impaction) in Vertex‐Vertex Type Twin Delivery
Authors: Uchino Koichi 
Published: August 2010

AbstractWe studied the fetal position in vertex‐vertex type twins in 6 impaction cases and in 23 cases of vaginal deliveries without impaction. The results obtained were as follows:(1) In 6 impaction cases, the presenting head of the first fetus was shown to be at the maternal pubic side and the head of the second fetus at the maternal sacral side.(2) In 23 cases without impaction, the presenting head of the first fetus was shown to be at the maternal sacral side and the head of the second fetus at the maternal pubic side.(3) There was a statistical significant difference between the 6 impaction cases and the 23 non impaction cases as determined by the Chi‐square test (p<0.001).Our study suggests that it is possible to predict the occurrence of impaction in vertex‐vertex type twin deliveries by examining the positional relationship of the presenting heads of the first and second fetuses.There was a higher possibility of impaction when the head and body of twin 1 was located in the maternal‐pubic position, while the head of twin 2 was in the sacral position.In contrast, impaction never occurred when the head and body of twin 1 was in the maternal‐sacral position and the head of twin 2 was in the pubic position.
A Comparison between the Preoperative and Operative Findings of Peritoneal Cytology in Patients with Endometrial Cancer
Authors: Sagawa Tadashi , Yamada Hideto , Sakuragi Noriaki , Fujimoto Seiichiro 
Published: August 2010

AbstractLaparoscopy and hysteroscopy were simultaneously performed to examine the in‐traperitoneal and intrauterine spread of endometrial cancer prior to surgery. Peritoneal cytology (PC) was examined before and after hysteroscopy and at the time of laparotomy. To elucidate the mechanisms by which endometrial cancer cells spread into the peritoneal cavity, the changes in PC in sequential samples and the association between PC and other prognostic factors were examined.

Of the patients who had negative PC before hysteroscopy, 3 patients exhibited positive PC from their operation materials (12.5%). It was suggested that leakage of endometrial cancer cells into the peritoneal cavity was induced by hysteroscopy in 2 patients and by endometrial biopsy in one patient.
Of those patients with no intraperitoneal lesions, 3 patients had positive PC in the prehysteroscopy samples (11.1%). A statistically significant association was found between pelvic node metastasis and positive PC in the prehysteroscopy samples.
Congenital Diaphragmatic Hernia Treated by Perinatal Stabilization
Authors: Iwanaka Tadashi , Tamura Masanori , Tanaka Kiyoshi , Komuro Hiroaki , Tsuchida Yoshiaki , Okai Takashi 
Published: August 2010

AbstractThe delay of surgery in conjunction with high‐frequency oscillation ventilation combined with preoperative stabilization is a standard treatment for congenital diaphragmatic hernia neonates in the high‐risk group. A new protocol of perinatal stabilization with this preoperative stabilization has been developed at the University of Tokyo Hospital. The most important components of this method of perinatal stabilization are cesarean section and the injection of morphine and pancuronium through the umbilical vein prior to ligation of the umbilical cord. In order to benefit from this treatment, congenital diaphragmatic hernia patients should be diagnosed antenatally by ultrasonography and be delivered by cesarean section. This protocol of perinatal stabilization appears effective in congenital diaphragmatic hernia patients.
A Case Report on Radiotherapy in Choriocarcinoma: A Life Saving Procedure
Authors: Vaid Neelam B. , Kaur Charanjeet , Vidya S. , Bahadur A.K. 
Published: August 2010

AbstractRadiation therapy was tried to control hemorrhage from uterine cavity in a case of choriocarcinoma in which surgery was not practically possible due to the presence of a large nodule extending from suburethral region up to anterior fornix involving the entire anterior vaginal wall and patient being in a very critical condition. Radiotherapy was found to be successful and life saving.
A Comparison of Enzyme‐Linked Immunosorbent Assay (ELISA) with Sperm Immobilization Test (SIT) in Detection of Antisperm Antibodies in Sera of Infertile Women
Authors: Lin Kuo‐Cherng , Su Jinu‐Huang , Lee Jau‐Nan 
Published: August 2010

AbstractIn the present study, an enzyme‐linked immunosorbent assay (ELISA) for antisperm antibodies was compared with a traditional standard sperm immobilization test (SIT) in sera from 158 infertile women in order to evaluate their clinical usefulness for various causes of infertility. Ten pregnant and unmarried women were used as the control group. There was a higher incidence rate by ELISA (13.9%) compared with that by SIT (10.1%) after examination of overall samples, although the difference was not statistically significant. The unexplained infertility group exhibited the highest incidence among the various causes of infertility in both of these two methods. Fifteen (93.8%) of 16 patients with positive SIT showed positive reaction in ELISA method, indicating that a close correlation exists between the two methods. The positive predictive value (54.5%) of ELISA was significantly (p<0.05) lower than that (87.5%) of SIT, as evaluated with the results of postcoital test (PCT) performed at periovulatory phase. This suggests that the ELISA method for antisperm antibodies is less specific than SIT in view of the PCT results. Nevertheless, no fresh sperms are not required for the ELISA examination. Thus, it seems that the ELISA method may provide a convenient and practical means for mass screening in detecting antisperm antibodies in clinical practice.
Prolactin Response to Suckling in a Group of Fully Breast Feeding Women during the Early Postpartum Period
Authors: Tennekoon Kamani H. , Arulambalam Preetha D. , Karunanayake Eric H. , Seneviratne Harsha R. 
Published: August 2010

AbstractProlactin response to suckling was studied in a group of fully breast feeding women (N= 58) between 4–6 weeks postpartum. Basal, suckling stimulated and the increment of prolactin showed wide individual variations. Basal prolactin concentrations varied from 140 to 4,600 mlU/l, suckling stimulated prolactin from 400 to 5,600 mlU/l and the increment of prolactin from 40 to 4,160 mlU/l. Basal (p = 0.0395) and suckling stimulated (p = 0.0423) prolactin concentrations significantly increased as the number of night breast feeds increased and the suckling stimulated (p = 0.0218) prolactin concentrations significantly increased as the number of breast feeds/24 h increased. However, the magnitude of the rise in prolactin in response to suckling was not dependent on basal prolactin concentration. Basal, suckling stimulated or the increment of prolactin were not significantly different between subjects having different breast feeding frequencies, when the subjects were grouped according to the number of breast feeds. These differences may be due to the large individual variation in prolactin concentrations seen in women having similar breast feeding frequencies which may arise from individual variations in hypotha‐lamic — pituitary response to suckling.