bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Higher BMI on Wound Complications Following Adolescent Breast Reduction: A Retrospective Study of 1215 Cases
Authors: Yu Victor J. , Pham Jason T. , Evans Adam G. , Guo Yifan 
Published: May 2024

Abstract

Background
Macromastia is a physically and psychologically distressing condition for adolescents. While reduction mammaplasty is often the best treatment, risk factors for adolescent wound complications remain unclear. This study aims to investigate the impact of obesity and other predictors of postoperative wound complications following adolescent reduction mammaplasty using a national database.

Methods
The 2012–2019 National Surgical Quality Improvement Program Pediatric (NSQIP-P) databases were reviewed to identify primary reduction mammaplasty encounters. World Health Organization Body Mass Index (BMI), alongside patient and case characteristics, were assessed for association for 30-day wound disruption or surgical site complications. Statistical analyses were performed to identify independent predictors for complications and determine a potential BMI cutoff for risk stratification.

Results
There were 1215 patients with an average age of 16.6 years. The average BMI was 30.7 kg/m2, and 593 (48.8%) patients were nonobese while 622 (51.2%) were obese. The incidence of complications was 5.27%. Independent predictors of complications included a BMI 35–39.9, BMI  > 40, and an American Society of Anesthesiologists (ASA) Classification  > 3. A receiver operating characteristic curve determined that a BMI of 34.6 can be a potential cutoff for increased complication risk.

Conclusions
Higher obesity increases risk of wound complications; however, complication rates remain low. A BMI of 34.6 is a potential screening metric for counseling and monitoring patients. Reduction mammaplasty should remain a viable option as it can significantly improve quality of life.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to Table of Contents or the online Instructions to Authors www.springer.com/00266.
Exploring polyphosphates in soil: presence, extractability, and contribution to microbial biomass phosphorus
Authors: Čapek Petr , Tupá Adéla , Choma Michal 
Published: May 2024

AbstractPolyphosphates (Poly-P) are known to fulfil several important physiological functions. Many microorganisms can accumulate large amounts of Poly-P in their biomass. Regardless of these facts, systematic research on Poly-P in soil is missing, probably due to the absence of any method of direct Poly-P quantification. In this study, we attempted to unequivocally prove the presence of Poly-P in the biomass of soil microorganisms and quantify their extractability and contribution to microbial biomass phosphorus. To do so, we combined several approaches that can indicate Poly-P presence in soil microbial biomass indirectly, i.e. growth of soil inoculum on media without phosphorus, associated with measurement of changes in the microbial biomass stoichiometry, and the colour of the microbial suspension stained by the Neisser method. All soil microbial communities exhibited growth on media without phosphorus. As the growth on this media depleted Poly-P content, the biomass carbon to phosphorus and nitrogen to phosphorus ratio increased and the colour of the microbial suspension stained by the Neisser method changed predictively. The associated Poly-P addition experiment indicated that the recovery of added Poly-P from soil in form of soluble reactive phosphorus in sodium bicarbonate extract may reach up to 93% mainly due to abiotic depolymerization. Using a simple stoichiometric model applied to measured data, we calculated that the Poly-P content of microbial biomass in our soils may be up to 45 or 70% of total microbial biomass phosphorus depending on the assumptions applied regarding parameter values. We discuss the magnitude of error associated with the measurement of soil microbial phosphorus due to the high extractability of Poly-P.
Online Multiset Submodular Cover
Authors: Halldórsson Magnús M. , Rawitz Dror 
Published: May 2024

AbstractWe study the Online Multiset Submodular Cover problem (OMSC), where we are given a universe U of elements and a collection of subsets $$\mathcal {S}\subseteq 2^U$$

S
⊆

2
U

. Each element $$u_j \in U$$

u
j

∈
U

is associated with a nonnegative, nondecreasing, submodular polynomially computable set function $$f_j$$

f
j

. Initially, the elements are uncovered, and therefore we pay a penalty per each unit of uncovered element. Subsets with various coverage and cost arrive online. Upon arrival of a new subset, the online algorithm must decide how many copies of the arriving subset to add to the solution. This decision is irrevocable, in the sense that the algorithm will not be able to add more copies of this subset in the future. On the other hand, the algorithm can drop copies of a subset, but such copies cannot be retrieved later. The goal is to minimize the total cost of subsets taken plus penalties for uncovered elements. We present an $$O(\sqrt{\rho _{\max }})$$

O
(

ρ
max

)

-competitive algorithm for OMSC that does not dismiss subset copies that were taken into the solution, but relies on prior knowledge of the value of $$\rho _{\max }$$

ρ
max

, where $$\rho _{\max }$$

ρ
max

is the maximum ratio, over all subsets, between the penalties covered by a subset and its cost. We provide an $$O\left( \log (\rho _{\max }) \sqrt{\rho _{\max }} \right) $$

O

log

(

ρ
max

)

ρ
max

-competitive algorithm for OMSC that does not rely on advance knowledge of $$\rho _{\max }$$

ρ
max

but uses dismissals of previously taken subsets. Finally, for the capacitated versions of the Online Multiset Multicover problem, we obtain an $$O(\sqrt{\rho _{\max }'})$$

O
(

ρ

max

′

)

-competitive algorithm when $$\rho _{\max }'$$

ρ

max

′

is known and an $$O\left( \log (\rho _{\max }') \sqrt{\rho _{\max }'} \right) $$

O

log

(

ρ

max

′

)

ρ

max

′

-competitive algorithm when $$\rho _{\max }'$$

ρ

max

′

is unknown, where $$\rho _{\max }'$$

ρ

max

′

is the maximum ratio over all subset incarnations between the penalties covered by this incarnation and its cost.
Dyslipidemia in children with chronic kidney disease—findings from the Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) study
Authors: Mencarelli Francesca , Azukaitis Karolis , Kirchner Marietta , Bayazit Aysun , Duzova Ali , Canpolat Nur , Bulut Ipek Kaplan , Obrycki Lukasz , Ranchin Bruno , Shroff Rukshana , Caliskan Salim , Candan Cengiz , Yilmaz Alev , Özcakar Zeynep Birsin , Halpay Harika , Kiyak Aysel , Erdogan Hakan , Gellermann Jutta , Balat Ayse , Melk Anette , Schaefer Franz , Querfeld Uwe 
Published: May 2024

Abstract
Background
Dyslipidemia is an important and modifiable risk factor for CVD in children with CKD.

Methods
In a cross-sectional study of baseline serum lipid levels in a large prospective cohort study of children with stage 3–5 (predialysis) CKD, frequencies of abnormal lipid levels and types of dyslipidemia were analyzed in the entire cohort and in subpopulations defined by fasting status or by the presence of nephrotic range proteinuria. Associated clinical and laboratory characteristics were determined by multivariable linear regression analysis.

Results
A total of 681 patients aged 12.2 ± 3.3 years with a mean eGFR of 26.9 ± 11.6 ml/min/1.73 m2 were included. Kidney diagnosis was classified as CAKUT in 69%, glomerulopathy in 8.4%, and other disorders in 22.6% of patients. Nephrotic range proteinuria (defined by a urinary albumin/creatinine ratio > 1.1 g/g) was present in 26.9%. Dyslipidemia was found in 71.8%, and high triglyceride (TG) levels were the most common abnormality (54.7%). Fasting status (38.9%) had no effect on dyslipidemia status. Except for a significant increase in TG in more advanced CKD, lipid levels and frequencies of dyslipidemia were not significantly different between CKD stages. Hypertriglyceridemia was associated with younger age, lower eGFR, shorter duration of CKD, higher body mass index (BMI-SDS), lower serum albumin, and higher diastolic blood pressure.

Conclusions
Dyslipidemia involving all lipid fractions, but mainly TG, is present in the majority of patients with CKD irrespective of CKD stage or fasting status and is significantly associated with other cardiovascular risk factors.

Graphical abstract
Longitudinal analysis of microcirculatory parameters in gingival tissues after tooth extraction in patients with different risk profiles for wound healing disorders – a pilot study
Authors: Mayr Alexandra , Ciper Nadja , Wahl Gerhard , Wildenhof Jan , Frede Stilla , Kirschneck Christian , Jäger Andreas , Götz Werner , Beisel-Memmert Svenja 
Published: May 2024

Abstract
Objectives
We aimed to establish a risk profile for intraoral wound healing disorders based on measurements of microcirculation in gingival tissues.

Materials and methods
Oxygen saturation (SO2) and blood flow in gingival tissues were measured with tissue spectrometry and laser doppler spectroscopy in 37 patients before/after tooth extractions. Patients were assigned to four groups: anamnestically and periodontally healthy patients (n = 7), anamnestically healthy but suffering from periodontitis (n = 10), anamnestically healthy but smoking and suffering from periodontitis (n = 10) and suffering from diabetes and periodontitis (n = 10). Measurements were performed at three different time points: Baseline measurement (T0), one day post extractionem (p.e.) (T1) and seven days p.e. (T2).

Results
Baseline SO2 values were higher in control patients (p = .038). This effect was most evident in comparison to smokers suffering from periodontitis (p = .042), followed by diabetics suffering from periodontitis (p = .09). An opposite trend was seen for blood flow. Patients suffering from periodontitis demonstrated higher blood flow values (p = .012). Five patients, which belonged to the group of smokers suffering from periodontitis, showed clinically a delayed wound healing.

Conclusion
Differences in SO2 and blood flow of gingival tissue could be detected in different groups of patients with existing periodontitis compared to control patients.

Clinical Relevance
Lower baseline SO2 values could be a warning signal for possible wound healing disorders after oral surgery.
A new method for detecting unilateral spatial neglect with tracing tasks using the Rey-Osterrieth complex figure: a pilot study
Authors: Ohama Rintaro , Matsumoto Shuji , Ohama Yumi , Yokoyama Katsuya , Shimodozono Megumi 
Published: May 2024

Abstract
Purpose
To explore efficacy of the “Rey-Osterrieth complex figure (ROCF) tracing task” as a new test to detect unilateral spatial neglect (USN).

Methods
Subjects were 40 healthy control (HC) and 20 right brain-damaged patients with (USN + , n = 10) or without USN (USN − , n = 10). After the ROCF copying task, the tracing task was performed under conditions that did not leave any tracing lines on the sample figure. Evaluation used the conventional 36-point scoring system, laterality index (LI) as the ratio of the left and right structure scores, and the number of overlaps for each of the left and right structures scored.

Results
In the tracing task, USN + showed a lower LI than HC. Furthermore, left-sided neglect was sometimes more evident than in the copying task. Regarding the total overlapping score, USN + showed a greater score than HC. The right-sided overlapping scores in USN + and USN − were also greater than that in HC. In the right brain-damaged subjects, clinically meaningful correlations were not found between evaluations in the ROCF tracing task and in conventional USN screening tests. Receiver-operating-characteristic analysis to test the power of detection showed moderate performance for the tracing LI (AUC = 0.76, 95% CI = 0.54–0.97), which was greater than that of other tests. Further, the total overlapping score in the tracing task showed sensitivity 0.9 (highest among the tests performed), specificity 0.5, and AUC 0.68 (95% CI = 0.43–0.92).

Conclusion
The ROCF tracing task might be a convenient method to detect USN and to reveal the extent of spatial working memory impairment.
The titers of antinuclear antibodies are associated with the degree of inflammation and organ damage in Primary Sjögren's Syndrome
Authors: Shao Huijun , Wu Yue , Tao Xinyu , Liu Qun , Ran Chenyu , Jin Li , Tao Jinhui 
Published: May 2024

AbstractPrimary Sjögren’s Syndrome (pSS) falls within the category of connective tissue diseases, characterized by the presence of autoantibodies such as antinuclear antibodies (ANA). However, according to the classification criteria for pSS, some patients may exhibit a negative result for autoantibodies. Patients with a negative result for autoantibodies may lack typical features of connective tissue diseases, and the immunological state as well as the extent of organ involvement and damage may differ from those with positive autoantibodies. This study aims to compare the clinical phenotypes of patients with positive and negative autoantibodies, providing insights for disease classification and treatment selection for clinicians. Patients with pSS were grouped based on the presence and titers of their autoantibodies. Subsequently, differences in organ damage and laboratory indicators were compared between these groups, aiming to analyze the value of autoantibody titers in assessing the condition of pSS. (1) Patients with positive ANA exhibited elevated levels of inflammatory indicators, including ESR, IgG levels, lip gland biopsy pathology grade, and overall organ involvement, in comparison with patients with negative ANA (P < 0.05). Furthermore, ANA-positivity correlated with a higher occurrence of multi-organ damage, particularly affecting the skin, mucous membranes, and the hematological system (P < 0.05). (2) As ANA titers increased, patients demonstrated elevated levels of IgG and an escalation in organ involvement (P < 0.05). (3) Patients in the positive autoantibody group (positive for antinuclear antibodies, anti-SSA, or anti-SSB antibodies) had higher IgG levels compared to the negative group (P < 0.05). (4) Patients with positive anti-SSA and anti-SSB antibodies exhibited higher levels of inflammatory indicators and IgG compared to other patients (P < 0.05); however, no significant differences were observed in terms of organ involvement and organ damage. Patients with positive ANA in pSS typically exhibit higher levels of inflammation and an increased likelihood of experiencing multi-organ damage. Furthermore, as the ANA titers increase, both inflammation levels and the risk of multi-organ damage also escalate. Additionally, the presence of anti-SSA and anti-SSB antibodies may contribute to an elevated risk of increased inflammation levels, but does not increase the risk of organ damage.
A DG-Enhancement of $${\text {D}}_{qc}(X)$$ with Applications in Deformation Theory
Authors: Meazzini Francesco 
Published: May 2024

AbstractIt is well-known that DG-enhancements of the unbounded derived category$${\text {D}}_{qc}(X)$$Dqc(X)of quasi-coherent sheaves on a schemeXare all equivalent to each other. Here we present an explicit model which leads to applications in deformation theory. In particular, we shall describe three models for derived endomorphisms of a quasi-coherent sheaf$$\mathcal {F}$$Fon a finite-dimensional Noetherian separated scheme (even if$$\mathcal {F}$$Fdoes not admit a locally free resolution). Moreover, these complexes are endowed with DG-Lie algebra structures, which we prove to control infinitesimal deformations of$$\mathcal {F}$$F.
Standardized transect walks outperform pan traps in assessing wild bee community in a Mediterranean protected area (Asinara National Park, Italy)
Authors: Lezzeri Matteo , Lozano Vanessa , Brundu Giuseppe , Floris Ignazio , Pusceddu Michelina , Quaranta Marino , Satta Alberto 
Published: May 2024

AbstractThe decline of pollinator insects in various parts of the world has increased the interest in studies on bee sampling. Because pollinator management and conservation policies depend on data representing their communities, knowledge of the systematic bias of sampling methods in relation to surrounding habitat is fundamental. This study examined the performance of standardized transect walks and colored pan traps considering differences in bee species richness, diversity, and composition, and the potential bias due to a different availability of floral sources throughout seasons. The study was conducted in a minor outlying island (Asinara, Italy), a natural park characterized by the prevalence of natural or semi-natural habitats and an Oceanic Pluviseasonal Mediterranean bioclimate. We found that transect and pan trap methods reflected different bee communities based on taxonomic families, genera, and species. In general, the transect method captured more varied samples than pan traps, despite the significantly lower number of individuals captured on transects. Moreover, pan traps captured more bees as floral abundance decreased, whereas transects showed greater bee abundance, richness, and diversity with increasing floral resource availability. In addition, 18 species out of the 68 observed in total were caught exclusively with pan traps, especially in July–October, when transect catches decreased due to substantial bloom reduction. Therefore, alternating the two methods according to season (i.e., transect in late winter-spring and pan trap in summer-autumn) might be the most suitable trade-off to obtain a better representation of the bee community by limiting sampling efforts and the negative impact on bee fauna.
Parental Risk and Protective Factors Associated with Bullying Victimization in Children and Adolescents: A Systematic Review and Meta-analysis
Authors: Grama Diana Ioana , Georgescu Raluca Diana , Coşa Iulia Maria , Dobrean Anca 
Published: May 2024

AbstractThe main objective of this meta-analysis was to investigate how modifiable parental factors are related to traditional and cyberbullying victimization in children and adolescents. A systematic literature search of modifiable parental factors associated with bullying victimization was conducted using PubMed, PsycINFO, Scopus, and Web of Science electronic databases. Meta-analyses were performed to assess the mean effect sizes of the associations between the broader categories of parental factors (risk and protective) and bullying victimization (traditional and cyber), as well as between specific parental factors and bullying victimization (traditional and cyber). The differential impact of maternal and paternal factors (risk and protective) was examined. Age and gender were tested as moderators. Out of the 13,171 records identified, 158 studies met the inclusion criteria. Larger evidence was found for the association between parental risk (i.e., authoritarian parenting, aversiveness, inter-parental conflict, over-involvement, permissive parenting, and withdrawal) and protective (i.e., authoritative parenting, autonomy granting, warmth, and monitoring) factors, respectively, and traditional bullying victimization, with parental warmth, aversiveness, and withdrawal being the only common related predictors for traditional and cyberbullying victimization. The effect sizes were generally small. Maternal and paternal factors showed similar patterns of association with both types of bullying victimization. Age had a moderating effect on the association between parental protective factors and cyberbullying victimization. Overall, the present findings suggest that parental factors are relevant in protecting or putting children at risk for bullying victimization, especially in the offline context.
The holocentricity in the dioecious nutmeg (Myristica fragrans) is not based on major satellite repeats
Authors: Kuo Yi-Tzu , Kurian Jacob Gigi , Schubert Veit , Fuchs Jörg , Melzer Michael , Muraleedharan Ananthu , Maruthachalam Ravi , Houben Andreas 
Published: May 2024

AbstractHolocentric species are characterized by the presence of centromeres throughout the length of the chromosomes. We confirmed the holocentricity of the dioecious, small chromosome-size species Myristica fragrans based on the chromosome-wide distribution of the centromere-specific protein KNL1, α-tubulin fibers, and the cell cycle-dependent histone H3 serine 28 phosphorylation (H3S28ph) mark. Each holocentromere is likely composed of, on average, ten centromere units, but none of the identified and in situ hybridized high-copy satellite repeats is centromere-specific. No sex-specific major repeats are present in the high-copy repeat composition of male or female plants, or a significant difference in genome size was detected. Therefore, it is unlikely that M. fragrans possesses heteromorphic sex chromosomes.
The effects of immersive virtual reality field trips upon student academic achievement, cognitive load, and multimodal presence in a social studies educational context
Authors: Alazmi Huda S. , Alemtairy Ghader M. 
Published: May 2024

AbstractThere is increasing educational interest in immersive virtual reality (IVR) applications which aid student learning and performance. However, few empirical studies have investigated the potential for implementing the technology in middle-school social studies classrooms. This study employed a quasi-experimental approach to address this issue, using pre- and post-test evaluations to measure academic achievement, and questionnaires to examine cognitive load and sense-of-presence. 48 seventh-grade students participated, split evenly between experimental and control groups. The experimental group received a systematic set of IVR-based social studies lessons via Head-Mounted Displays, while the control group covered identical content conventionally. Experimental group participants attained higher academic achievement with lower cognitive loading than control group students. The experimental group also experienced high levels of multimodal presence (physical, social, and self). This study yielded empirical evidence demonstrating the potential benefits which IVR offers social studies education. Furthermore, it provides an example for how effective, IVR-based social studies lessons can be developed.
First transcriptomic insight into the working muscles of racing pigeons during a competition flight
Authors: Stefaniuk-Szmukier Monika , Szmatoła Tomasz , Pustelnik Agnieszka , Ropka-Molik Katarzyna 
Published: May 2024

Abstract

Background
The currently known homing pigeon is a result of a sharp one-sided selection for flight characteristics focused on speed, endurance, and spatial orientation. This has led to extremely well-adapted athletic phenotypes in racing birds.

Methods
Here, we identify genes and pathways contributing to exercise adaptation in sport pigeons by applying next-generation transcriptome sequencing of m.pectoralis muscle samples, collected before and after a 300 km competition flight.

Results
The analysis of differentially expressed genes pictured the central role of pathways involved in fuel selection and muscle maintenance during flight, with a set of genes, in which variations may therefore be exploited for genetic improvement of the racing pigeon population towards specific categories of competition flights.

Conclusions
The presented results are a background to understanding the genetic processes in the muscles of birds during flight and also are the starting point of further selection of genetic markers associated with racing performance in carrier pigeons.