bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Deltahedral Zintl Ions of Tin: Synthesis, Structure, and Reactivity
Authors: Sevov Slavi C. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cyanide‐Bridged Complexes of Transition Metals: A Molecular Magnetism Perspective
Authors: Shatruk Michael , Avendano Carolina , Dunbar Kim R. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recycling and Catalytic Approaches for the Development of a Rare‐Metal‐Free Synthetic Method Using Hypervalent Iodine Reagent
Authors: Dohi Toshifumi 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Adenosyl Radical: Reagent and Catalyst in Enzyme Reactions
Authors: Marsh E. Neil G. , Patterson Dustin P. , Li Lei 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rate Constants for Decarboxylation Reactions Calculated Using No Barrier Theory
Authors: Guthrie J. Peter , Peiris Sriyawathie , Simkin Margaret , Wang Yun 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Spinosyn Family of Insecticides: Realizing the Potential of Natural Products Research
Authors: Kirst Herbert A. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nano‐Combinatorial Chemistry Strategy for Nanotechnology Research.
Authors: Su Gaoxing , Yan Bing 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Halogenated α‐Amino Acids
Authors: Strickland Madeleine , Willis Christine L. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of N‐Alkyl Amino Acids
Authors: Aurelio Luigi , Hughes Andrew B. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Addition to Carbonyl Compounds: Aldehydes/Ketones
Authors: Chen Jia‐Rong , Xiao Wen‐Jing 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rational Design of Dynamic Ammonium Salt Catalysts Towards More Flexible and Selective Function
Authors: Ishihara Kazuaki 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: General Aspects and Historical Background (Friedel—Crafts Alkylation Reactions)
Authors: Bandini Marco 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Organic Synthesis via Organocatalysis
Authors: Melchiorre Paolo 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Epigenome Manipulation as a Pathway to New Natural Product Scaffolds and Their Congeners
Authors: Cichewicz Robert H. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biosynthesis and Biomimetic Synthesis of Alkaloids Isolated from Plants of the Nitraria and Myrioneuron Genera: An Unusual Lysine‐Based Metabolism
Authors: Gravel Edmond , Poupon Erwan 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Prenylated Indole Derivatives from Fungi: Structure Diversity, Biological Activities, Biosynthesis and Chemoenzymatic Synthesis
Authors: Li Shu‐Ming 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Resolution and absolute configuration assignment of a chiral hemicryptophane molecular cage
Authors: Perraud Olivier , Raytchev Pascal Dimitrov , Martinez Alexandre , Dutasta Jean‐Pierre 
Published: May 2010

AbstractThe racemic hemicryptophane molecular cage 2 was resolved by semipreparative HPLC on Whelk‐O1 column. The absolute configuration of each isolated enantiomer was established from the analysis of their circular dichroism spectra and assigned as P‐(+)‐2 and M‐(−)‐2. Chirality, 2010. © 2010 Wiley‐Liss, Inc.
The effects of impeller speed and holdup on mean drop size in a mixer settler with spiral‐type impeller
Authors: Khakpay Amir , Abolghasemi Hossein 
Published: May 2010

AbstractAn experimental investigation has been carried out in order to analyse the drop size distributions of liquid–liquid dispersion in a single stage mixer settler extractor. In this paper, the effects of the impeller speed and the holdup on mean drops size, D32, have been investigated. D32 was decreased with an increase in the impeller speed. Furthermore, D32 was increased with an increase in the holdup. In addition, a new and modified correlation was established based on these results. The average absolute relative deviation is 3.36%.
Liposome contrast agent for CT‐based detection and localization of neoplastic and inflammatory lesions in rabbits: validation with FDG‐PET and histology
Authors: Zheng Jinzi , Allen Christine , Serra Stefano , Vines Douglass , Charron Martin , Jaffray David A. 
Published: May 2010

AbstractPurposeThis study was aimed at assessing the performance of a liposome‐based computed tomography (CT) contrast agent to detect tumor and inflammatory lesions in a rabbit model relative to 18F‐fluorodeoxyglucose‐ positron emission tomography (FDG‐PET).Materials and MethodsNine New Zealand White rabbits were inoculated with a cell suspension obtained from the tumor tissue of a donor rabbit bearing VX2 carcinoma. Spontaneously formed inflammatory lesions were identified in the skeletal muscles of six of the nine animals. The CT liposome agent (185 ± 37 mg/kg of iodine) was administered intravenously 7 days following tumor inoculation. The PET/CT imaging session took place five days post‐liposome contrast administration and 1 h post 18F‐FDG injection (30.3 ± 5.1 MBq/kg). Approximately 20 h post‐imaging, the tumor and inflammatory lesions were excised for histo‐pathology assessment.ResultsLiposome‐CT identified the same number of primary tumors as FDG‐PET (nine lesions, volumes = 0.07–7.01 cm3, SUVmax = 1.5–10.9, HUmean = 103.0–140.6). It also detected 25 inflammatory lesions (volumes = 0.01–2.73 cm3, HUmean = 114.5–268.6), while FDG‐PET identified seven (volumes = 0.05–1.04 cm3, SUVmax = 2.7–7.1). Differences in the mean CT signal (HUmean) between the tumor and inflammatory lesions were statistically significant (p < 0.0001). Partial volume adjusted SUVmax values for the two lesion types calculated from the FDG‐PET data set did not yield a significant difference (p > 0.15).ConclusionThese results demonstrate that liposome‐CT can be considered for effective screening of neoplastic and inflammatory diseases, as well as subsequent image‐guided biopsy. Moreover, the differential accumulation of the liposomal agent at tumor and inflammatory sites highlights its potential role in increasing the specificity of image‐based diagnosis. Copyright © 2010 John Wiley & Sons, Ltd.
Platelet‐derived growth factor receptor β inhibition increases tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) sensitivity
Authors: Wang Yongxin , Mandal Deendayal , Wang Suizhau , Kleinerman Eugenie S. , Pollock Raphael E. , Lev Dina , Hayes‐Jordan Andrea 
Published: May 2010

AbstractBACKGROUND:There is a crucial need for better therapeutic approaches for the treatment of Ewing sarcoma (EWS). Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces apoptosis in EWS cells in vitro. However, in vivo, acquired resistance to TRAIL is a major limiting factor. Platelet‐derived growth factor receptor‐β (PDGFR‐β) is highly expressed on EWS cells. Thus, the authors evaluated whether PDGFR‐β blockade could sensitize EWS cells to TRAIL‐induced apoptosis in vitro and in vivo.METHODS:The effect of combined imatinib mesylate (Gleevec) and TRAIL on EWS cell growth and apoptosis was tested in vitro. Stable PDGFR‐β knockdown in EWS cells was achieved by short‐hairpin RNA transduction, and TRAIL sensitivity of these cells was measured. Expression of death receptors was measured by fluorescence‐activated cell‐sorting (FACS) analysis, and caspase 8 activity was evaluated by Western blot analysis. An orthotopic human xenograft model of EWS growth and spontaneous metastasis in nude mice was used to assess the in vivo affect of combined imatinib mesylate and TRAIL.RESULTS:Imatinib mesylate induced a significant TRAIL proapoptotic effect in EWS cells in vitro. Specific PDGFR‐β silencing in EWS cells enhanced the effects of TRAIL, possibly through an increase in the expression of death receptors 4 and 5. The combination of imatinib mesylate and TRAIL significantly inhibited the growth of primary tumors and decreased the incidence of spontaneous EWS pulmonary metastasis compared with either drug alone.CONCLUSIONS:PDGFR‐β blockade combined with TRAIL resulted in antihuman EWS activity in vitro and in vivo, suggesting the possibility that combining these treatments will improve anti‐EWS therapy. Cancer 2010. © 2010 American Cancer Society.
Dasatinib in imatinib‐resistant or imatinib‐intolerant chronic myeloid leukemia in blast phase after 2 years of follow‐up in a phase 3 study
Authors: Saglio Giuseppe , Hochhaus Andreas , Goh Yeow Tee , Masszi Tamas , Pasquini Ricardo , Maloisel Frederic , Erben Philipp , Cortes Jorge , Paquette Ronald , Bradley‐Garelik M. Brigid , Zhu Chao , Dombret Herve 
Published: May 2010

AbstractBACKGROUND:In a phase 3 study, the authors assessed the effects of dasatinib at doses of 140 mg once daily and 70 mg twice daily in patients who had either chronic myeloid leukemia (CML) in advanced phases or Philadelphia chromosome‐positive acute lymphoblastic leukemia and were resistant or intolerant to imatinib. In the current report, the results for patients with CML in blast phase after 2 years of follow‐up are reported.METHODS:Patients were stratified according to whether they had CML in myeloid blast phase (MBP‐CML) or in lymphoid blast phase (LBP‐CML) and were randomized (1:1) within each stratum to receive either oral dasatinib 140 mg once daily or 70 mg twice daily.RESULTS:In patients with MBP‐CML, the major hematologic response rate was 28% for both regimens; and, in patients with LBP‐CML, the major hematologic response rate was 42% for once‐daily dasatinib and 32% for twice‐daily dasatinib. The major cytogenetic response rates were 25% for once‐daily dasatinib and 28% for twice‐daily dasatinib in patients with MBP‐CML, and the respective rates in patients with LBP‐CML were 50% and 40%. The overall survival rate at 24 months was 24% for once‐daily dasatinib and 28% for twice‐daily dasatinib in patients with MBP‐CML, and the respective values in patients with LBP‐CML were 21% and 16%. Adverse events indicated a trend toward improved tolerability for the once‐daily regimen.CONCLUSIONS:The current results suggested that dasatinib 140 mg once daily had similar efficacy and improved tolerability relative to the 70‐mg twice‐daily regimen in patients with imatinib‐resistant, blast phase CML. Cancer 2010. © 2010 American Cancer Society.
Access to hematopoietic stem cell transplantation
Authors: Joshua Thomas V. , Rizzo J. Douglas , Zhang Mei‐Jie , Hari Parameswaran N. , Kurian Seira , Pasquini Marcelo , Majhail Navneet S. , Lee Stephanie J. , Horowitz Mary M. 
Published: May 2010

AbstractBACKGROUND:The purpose of the current study was to determine whether the use of hematopoietic stem cell transplantation (HCT) to treat leukemia, lymphoma, or multiple myeloma (MM) differs by race and sex.METHODS:The annual incidence of leukemia, lymphoma, and MM was estimated in the United States in people aged <70 years by race and sex using the Surveillance, Epidemiology, and End Results (SEER) cancer registry between 1997 and 2002 and US census reports for the year 2000. The annual incidence of autologous, human leukocyte antigen (HLA) identical sibling, and unrelated HCT performed in these groups was estimated using Center for International Blood and Marrow Transplant Research data from 1997 through 2002. Logistic regression analysis was used to calculate the age‐adjusted odds ratio (OR) of receiving HCT for Caucasians versus African Americans and for men versus women.RESULTS:The likelihood of undergoing HCT was found to be higher for Caucasians than for African Americans (OR, 1.40; 95% confidence interval [95% CI], 1.34‐1.46). This difference existed for each type of HCT: autologous (OR, 1.24; 95% CI, 1.19‐1.30), HLA identical sibling (OR, 1.59; 95% CI, 1.46‐1.74), and unrelated donor (OR, 2.02; 95% CI, 1.75‐2.33). Overall, men were more likely than women to receive HCT (OR, 1.07; 95% CI, 1.05‐1.1 [P < .0001]); however, this difference was found to be significant only for autologous HCT (OR, 1.10; 95% CI, 1.07‐1.13 [P < .0001]).CONCLUSIONS:HCT is more frequently used to treat leukemia, lymphoma, and MM in Caucasians than in African American individuals. African Americans have lower rates of both autologous and allogeneic HCT, indicating that donor availability cannot fully explain the differences. Women are less likely than men to receive autologous HCT for reasons unexplained by age or disease status. Cancer 2010. © 2010 American Cancer Society.
Reciprocity and burnout in direct care staff
Authors: Rose John , Madurai Teresa , Thomas Kate , Duffy Brigid , Oyebode Jan 
Published: May 2010

AbstractUnderstanding the perceptions of direct care staff of their reciprocal relationships at work and levels of burnout may help us improve not only their psychological health but also the service they provide. A cross‐sectional survey was undertaken with direct care staff who worked with children, older people and people with intellectual disabilities in residential settings. Staffs were asked to report their levels of burnout and perceived reciprocity in the relationship they had with service users, other staff and the organisation they worked for. Significant relationships were found between some burnout and reciprocity measures. ‘Under benefit’ in relationships with service users, colleagues and the organization was related to emotional exhaustion. ‘Under benefit’ in organizational and staff relationships was related to increased depersonalization. Reciprocity is a potentially useful concept for understanding differences in relationships across a broad range of staff and use of the reciprocity questionnaire in this study allows for comparison between diverse groups. The importance of relationships with the employing organization is highlighted in this sample and suggests that burnout is not solely linked with lack of reciprocity in the caregiving relationship per se. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Direct care staff are important intermediaries for the work of many clinical psychologists and research suggests that their well‐being can influence the quality of care they provide.• There are similarities between care staff who work across different client groups.• This paper describes the development of a methodology that examines reciprocity in relationships with service users, staff and organization.• This framework is shown to be useful in exploring staff relationships and concerns that may facilitate clinical work with staff and stimulate research.
Experiential learning in psychotherapy: ropes course exposures as an adjunct to inpatient treatment
Authors: Wolf Markus , Mehl Kilian 
Published: May 2010

AbstractExposures to a high‐ropes course are introduced as an adjunct intervention in the therapy of psychotherapy patients. A controlled study was conducted to investigate the effectiveness of high‐ropes exposures as an add‐on to inpatient treatment in a naturalistic setting. In a sample of 247 patients, depressive symptoms, trait anxiety, locus of control and self‐efficacy were assessed at admission and discharge of treatment and at 24‐month follow‐up. Follow‐up data were available for 104 patients who attended the ropes courses and 53 control patients who underwent an inpatient treatment programme as usual. At the end of treatment, more high‐rope participants showed clinically significant change on trait anxiety than controls but not regarding depressive symptoms. High‐rope participants showed better follow‐up outcomes than controls in trait anxiety and self‐efficacy but not in depressive symptoms and external locus of control. Moreover, during follow‐up, in the high‐rope group, more patients showed reliable improvements and fewer patients showed reliable deteriorations in trait anxiety as compared with controls. The study gives a preliminary indication that the high‐rope interventions are a feasible and valuable add‐on to inpatient psychotherapy. The study design, sample composition and loss to follow‐up are discussed as potential limitations of the study. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Based on the principles of experiential learning, outdoor ropes courses are a means for the facilitation of personal growth and promotion of individual coping skills.• A ropes course intervention was evaluated as an add‐on to a psychotherapy inpatient programme.• In a diagnostically mixed inpatient sample, participation in ropes course exposures seemed to be related with better long‐term outcomes on personality variables—trait anxiety and self‐efficacy—but not regarding depressive symptoms and state anxiety.• Interventions that draw upon experience and group action might be a valuable addition to talking psychotherapy.
Psychometric properties of the panic disorder severity scale: clinician‐administered and self‐report versions
Authors: Wuyek Lisa A. , Antony Martin M. , McCabe Randi E. 
Published: May 2010

AbstractThe Panic Disorder Severity Scale (PDSS) is a seven‐item scale designed to assess overall severity of panic disorder symptoms. Although the PDSS is widely used, there have been limited independent studies confirming reliability and validity, particularly of the self‐report version of the PDSS, and even fewer studies directly comparing the two versions. Given the need for psychometrically sound measures that comprehensively assess the main features of panic disorder, this study examined the psychometric properties of both the clinician‐administered and self‐report versions of the PDSS. As the PDSS targets symptom severity across a number of specific domains, PDSS items were compared to several scales designed to measure similar constructs, including the Anxiety Sensitivity Index, Illness Intrusiveness Ratings Scale, Mobility Inventory for Agoraphobia and Agoraphobic Cognitions Questionnaire. Results indicated acceptable reliability for both the clinician‐administered and self‐report versions. Results indicated acceptable validity for the clinician‐administered PDSS and promising validity for the self‐report. However, correlations between both versions of the PDSS and comparison measures were lower than predicted. Results also indicated that scores on the self‐report and clinician‐administered versions were significantly associated, although correlations between specific PDSS items on the two versions were also lower than expected. Results suggest that total scores on each of the PDSS versions provide a useful indication of panic‐related severity. However, clinicians and researchers are cautioned against relying on scores from individual items to measure specific constructs due to their poor specificity. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• Results indicated acceptable validity for the clinician‐administered PDSS and promising validity for the self‐report, and suggest that total scores on each version provide a useful indication of panic‐related severity. However, clinicians and researchers are cautioned against relying on scores from individual items to measure specific constructs due to their poor specificity.