bluuebunny/crossref_metadata_2025_split huggingface dataset:
Économie de la fonctionnalité. Une nouvelle synergie entre le territoire, la firme et le consommateur ?
Authors: Vaileanu-Paun Ingrid , Boutillier Sophie 
Published: February 2012

Résumé L’intérêt de cet article se situe dans le contexte de l’évolution des stratégies des entreprises permettant de contribuer à une croissance économique découplée du flux des matières et répondant aux enjeux écologiques et sociaux des territoires. Dans le cadre général des interrogations sur les réponses possibles aux crises écologiques, économiques, financières et énergétiques, l’article traite des changements des stratégies de création et d’évaluation de la valeur par les entreprises et par les territoires. On s’interroge sur l’émergence d’un paradigme de production/consommation renouvelé intégrant ex ante les externalités négatives et positives dans le processus économique. L’économie de la fonctionnalité s’inscrit ainsi dans une dynamique historique et une redéfinition des relations entre l’entreprise, le consommateur et le territoire. Codes JEL : L22, L53, O33
Stratégies de responsabilité sociale d'entreprise des acteurs BIO en Tunisie
Authors: Ghozzi-Nekhili Chiraz , Kamoun-Chouk Souad 
Published: February 2012

Résumé Les opérateurs économiques sont désormais questionnés, non seulement sur leurs résultats financiers mais aussi sur leur équité sociale et leur impact environnemental. Le concept de Responsabilité Sociale de l’Entreprise (RSE) repose sur l’ensemble des obligations qui pèsent sur elle dans sa gestion de ses relations avec ses différentes parties prenantes externes et internes. La Tunisie est classée première en Afrique en termes de surfaces certifiées en BIO. Ce secteur bénéficie d’une attention particulière de la part du gouvernement. Le cahier des charges régissant le secteur ne contient, cependant, aucune incitation pour l’adoption d’une stratégie RSE intégrale du moins explicitement. La culture BIO semble être perçue par les institutions de l’Etat tunisien comme un nouveau créneau porteur et une quête d’avantage compétitif. La question de recherche à laquelle nous tentons de répondre est la suivante : Dans quelle mesure la perception du BIO par les institutionnels, qui transparaît des études réalisées dans ce domaine, peut-elle influencer le comportement des opérateurs de la filière ? Pour répondre à cette question, nous avons mobilisé la typologie d’Acquier (2008). L’approche empirique s’est basée sur l’analyse documentaire d’études réalisées par deux agences nationales de promotion de l’investissement. Ce qui a permis de montrer le peu d’intérêt porté aux parties prenantes autres que le consommateur étranger. La stratégie RSE des opérateurs qui pourrait être adoptée, serait de type greenwashing. Code JEL : M1, M14
Le secteur du bâtiment face aux enjeux du développement durable : logiques d'innovation et/ou problématiques du changement
Authors: Deshayes Philippe 
Published: February 2012

Résumé Le « choc » du développement durable sur le secteur du bâtiment témoigne exemplairement de l’imbrication étroite entre les innovations elles-mêmes, les pratiques professionnelles et les représentations des parties prenantes. La question soulevée par cet article est celle de savoir s’il convient d’inscrire les transformations en cours du secteur du bâtiment dans les seules problématiques de l’innovation qui sont issues de notre modèle industriel de croissance. Le secteur du bâtiment ne peut-il pas apparaître comme une opportunité de questionnement vis-à-vis de ce modèle industriel et, plus largement, du lien entre pratiques professionnelles et pratiques sociales ? Au-delà, le secteur du bâtiment et de la construction n’apparaîtrait-il pas comme exemplaire pour penser les renouvellements des pratiques de l’industrie face aux enjeux en cours et à venir du développement durable ? Codes JEL : L14, L22, L74, O33, Q01
Essential Role for CAML in Follicular B Cell Survival and Homeostasis
Authors: Zane Nicholas A. , Gundelach Justin H. , Lindquist Lonn D. , Bram Richard J. 
Published: February 2012

Abstract
Calcium-modulating cyclophilin ligand (CAML) is a ubiquitously expressed protein that is important during thymopoiesis. However, whether it serves a function in mature lymphocytes is unknown. In this article, we show that CAML is essential for survival of peripheral follicular (Fo) B cells. Conditional deletion of CAML in CD19-Cre transgenic mice caused a significant reduction in Fo cell numbers and increased rates of homeostatic proliferation. CAML-deficient Fo cells showed increased cellular turnover and normal proliferative ability. Although CAML-deficient Fo cells responded to AgR stimulation and to B cell activating factor, they displayed decreased survival and increased apoptosis following stimulation with LPS and IL-4 in vitro. Failure to survive was not due to aberrant B cell development in the absence of CAML, because induced deletion of the gene in mature cells resulted in a similar phenotype. These data establish an essential and ongoing role for CAML in the long-term survival of mature B cells.
MF59 and Pam3CSK4 Boost Adaptive Responses to Influenza Subunit Vaccine through an IFN Type I-Independent Mechanism of Action
Authors: Caproni Elena , Tritto Elaine , Cortese Mario , Muzzi Alessandro , Mosca Flaviana , Monaci Elisabetta , Baudner Barbara , Seubert Anja , De Gregorio Ennio 
Published: February 2012

Abstract
The innate immune pathways induced by adjuvants required to increase adaptive responses to influenza subunit vaccines are not well characterized. We profiled different TLR-independent (MF59 and alum) and TLR-dependent (CpG, resiquimod, and Pam3CSK4) adjuvants for the ability to increase the immunogenicity to a trivalent influenza seasonal subunit vaccine and to tetanus toxoid (TT) in mouse. Although all adjuvants boosted the Ab responses to TT, only MF59 and Pam3CSK4 were able to enhance hemagglutinin Ab responses. To identify innate immune correlates of adjuvanticity to influenza subunit vaccine, we investigated the gene signatures induced by each adjuvant in vitro in splenocytes and in vivo in muscle and lymph nodes using DNA microarrays. We found that flu adjuvanticity correlates with the upregulation of proinflammatory genes and other genes involved in leukocyte transendothelial migration at the vaccine injection site. Confocal and FACS analysis confirmed that MF59 and Pam3CSK4 were the strongest inducers of blood cell recruitment in the muscle compared with the other adjuvants tested. Even though it has been proposed that IFN type I is required for adjuvanticity to influenza vaccines, we found that MF59 and Pam3CSK4 were not good inducers of IFN-related innate immunity pathways. By contrast, resiquimod failed to enhance the adaptive response to flu despite a strong activation of the IFN pathway in muscle and lymph nodes. By blocking IFN type I receptor through a mAb, we confirmed that the adjuvanticity of MF59 and Pam3CSK4 to a trivalent influenza vaccine and to TT is IFN independent.
The Neoteny Barrier: Seeking Respect for the Non-Cute
Authors: Estren Mark J. 
Published: February 2012

Abstract
A foundational human attraction to mammalian neoteny may be crucial for preservation of our own species, but it can be counterproductive in relationships between humans and other animals. The deeply rooted human psychological attraction to and preference for anthropomorphically viewed neotenic characteristics explains why some animals, whether endangered or not, receive far more public attention and scientific study than others. An understanding of the neoteny barrier makes it possible to find ways around it: The barrier may not be possible to break, but it can be modified by scientific awareness of its existence and an alteration of public perception of value to include animals who would not, in neotenic terms, be considered cute.
Opening the Door: Non-Veterinarians and the Practice of Complementary and Alternative Veterinary Medicine
Authors: Schommer Megan 
Published: February 2012

Abstract
Growing interest in complementary and alternative veterinary medicine (CAVM) has sparked a debate among veterinarians, who claim such therapeutic modalities fall under the purview of veterinary medicine, and non-veterinarians, who argue that several modalities do not require the rigorous training of a veterinarian to be performed safely. The veterinary profession must proactively redefine its definition of the practice of veterinary medicine in the face of increasing challenges to state practice acts. By looking to human medicine as a model for how to balance conventional and alternative modalities, the profession can develop a system that provides animal caregivers access to CAVM while still safeguarding animal health.
Laying the Foundations for an International Animal Protection Regime
Authors: Otter Caley , O’Sullivan Siobhan , Ross Sandy 
Published: February 2012

Abstract
In this article we consider what form a future supranational animal protection regime might take. We conclude that no such regime exists at present, although one is likely to develop over the next couple of decades, with two viable options already on the horizon. One model would see the role of the World Organisation for Animal Health (OIE) extended, whereas the other would occur within the context of the United Nations (UN). The former would suit agricultural interests, whereas the latter would probably appeal to so-called new welfarists. However, neither is likely to satisfy animal rights advocates because both regimes assume animals can be legitimately traded and utilized as means to human ends.
Some Ancient and Modern Views on the Expression of Shame in Animals
Authors: Newmyer Stephen T. 
Published: February 2012

Abstract
Greco-Roman philosophers and historians frequently attempted to define the human being vis-á-vis other animals by isolating capacities, intellectual, physical, and emotional, judged unique to humans. The Stoic claim that only humans have a sense of shame because only humans are rational and therefore capable of emotions, which entail reasoning, was contradicted by other philosophers and naturalists who argued that some animal behaviors were analogous to behavior in humans that indicate shame. Ancient debates on both sides of the issue of animal emotions are paralleled in current philosophy and cognitive ethology employing anecdotal and anthropomorphizing arguments that mirror classical examples.
Toward a Theory of Justice for Animals
Authors: Garner Robert 
Published: February 2012

Abstract
This highly recommended book explores the animal ethics debate from the perspective of Western political thought, offering the reader not only a survey but also the framework for an original interest-based theory of animal rights. Cochrane’s operating definition of justice is of limited use, and the author is perhaps too uncritical of the utility of employing justice as a means to protect the interests of animals. It is suggested, too, that an account of the political theory of animal rights can invoke profitably the debate between exponents of ideal and non-ideal theories of justice.
Interplay between Bimolecular Recombination and Carrier Transport Distances in Bulk Heterojunction Organic Solar Cells
Authors: Tumbleston John R. , Liu Yingchi , Samulski Edward T. , Lopez Rene 
Published: February 2012

AbstractIn this work, it is demonstrated that bimolecular recombination depends on the distance that free carriers are required to travel in transit to the electrodes in bulk heterojunction organic solar cells. By employing semi‐transparent devices, the carrier transport distance can be controlled via the local light absorption profile with an appropriate choice of the illumination side and incident wavelength. Using a series of light intensity‐dependent measurements, bimolecular recombination is shown to depend on the distance electrons or holes are required to transit the active layer. This effect is demonstrated for three different bulk heterojunction blends, where the restrictive carrier that causes the onset of recombination is identified. The mobility‐lifetime products of the limiting carriers are also estimated using a simple model for carrier extraction, where similar values are obtained regardless of the absorption profile. Implications for 1‐sun performance are also discussed, which provide guidelines for fabricating devices with thicker active layers capable of maximizing light absorption without succumbing to recombination losses.
On separation efficiency
Authors: Cussler E. L. , Dutta Binay K. 
Published: February 2012

AbstractRising energy costs have renewed interest in energy efficient separations. Such efficiencies can be defined as the free energy of unmixing divided by the work done on and the heat added to the process. The greatest efficiencies occur when the energy cost far exceeds any capital cost. In this limit, rate processes are not important, and efficiency is governed by thermodynamics. Efficiencies for gas absorption and stripping are then typically around 50%. The efficiencies of liquid–liquid extractions are lower, especially when one solute is wanted at higher concentration. The efficiencies of membrane separations are higher, but these require high pressure, normally obtained mechanically. As a result, membrane efficiencies should be reduced by any Carnot efficiency of generating the mechanical energy. These results, which are consistent with earlier estimates for distillation, have implications for carbon dioxide capture as a route to mitigating global warming. © 2012 American Institute of Chemical Engineers AIChE J, 2012
Preserving workers' dignity in workers' compensation systems: An international perspective
Authors: Lippel Katherine 
Published: February 2012

AbstractBackgroundWorkers' compensation systems are among the most generous disability insurance systems in North America, although they are also known to be potentially adversarial and may have iatrogenic effects on claimants. This article examines issues to be considered to ensure fair compensation provided in a way that respects the dignity of workers.MethodsAn overview of the literature on characteristics and effects of workers' compensation systems is followed by an analysis based on classic legal methods, including those of comparative law, complemented with interview data to examine three models of disability compensation.ResultsThe first part of the article identifies cross cutting issues to be considered in the examination of the equity of compensation systems and the protection of the dignity of claimants. These include three underpinnings of workers' compensation: the links between a “no‐fault” system and the adversarial process, the appropriate use of medical and scientific evidence in the determination of compensability and the application of appropriate measures for promoting return to work. The second part looks at accident compensation in New Zealand, where compensation is available regardless of the cause of the accident, and disability insurance in the Netherlands, where compensation is available regardless of the cause of the disability. It then describes a composite of characteristics favorable to equity drawn from the thirteen workers' compensation systems in Canada.ConclusionSystems that succeed in reducing opportunities for adversarial interactions and that provide substantive protection could better promote the dignity of claimants. Am. J. Ind. Med. 55:519–536, 2012. © 2012 Wiley Periodicals, Inc.
Karyotype/phenotype correlation in partial trisomies of the long arm of chromosome 16: Case report and review of literature
Authors: Laus Ana C. , Baratela Wagner A.R. , Laureano Lucimar A.F. , Santos Silvio A. , Huber Jair , Ramos Ester S. , Rebelo Camila C. , Squire Jeremy A. , Martelli Lucia 
Published: February 2012

AbstractTrisomy 16q is a clinically recognizable entity presenting with a wide spectrum of abnormalities. Only five infants with a diagnosis of partial trisomy 16q13 → qter have been previously reported, and all died during the first year of life. We report the clinical and molecular cytogenetic findings in a patient with trisomy 16q13 → qter due to the presence of a supernumerary marker chromosome (SMC). The child presented with microcephaly, ambiguous genitalia, cardiac malformations and dysmorphic features. Cytogenetic investigation using GTG‐banding, spectral karyotyping (SKY) and fluorescence in situ hybridization analyses revealed an SMC of maternal origin with karyotype der(15)t(15;16)(q13;q13). Specific genotype–phenotype correlations among different segments of the 16q region cannot yet be defined. We suggest that the involvement of the entire region spanning from 16q11 to 16q22 is necessary for the characteristic phenotype of the trisomy 16q. © 2012 Wiley Periodicals, Inc.
Hydrocephalus with Hirschsprung disease: Severe end of X‐linked hydrocephalus spectrum
Authors: Takenouchi Toshiki , Nakazawa Mie , Kanemura Yonehiro , Shimozato Sachiko , Yamasaki Mami , Takahashi Takao , Kosaki Kenjiro 
Published: February 2012

AbstractL1CAM molecule is a cell adhesion molecule in nervous and enteric systems and is responsible for X‐linked hydrocephalus (XLH) spectrum, which is a rare condition with severe congenital hydrocephalus, dysgenesis of the corpus callosum, intellectual disability, spasticity, and adducted thumbs. Several cases of XLH accompanied by Hirschsprung disease (HSCR) have been reported in the literature, but whether HSCR results from a gain‐of‐function mutation in cases with XLH, i.e., a neomorphic mutation, or the severe end of the L1CAM mutation spectrum remains unclear. The present patient was a Japanese boy with severe congenital hydrocephalus with aqueductal stenosis as well as hypoplasia of the corpus callosum. HSCR had been confirmed by a biopsy. A mutation analysis of the L1CAM gene showed a C61T mutation in exon 1, resulting in a truncating nonsense mutation at amino acid position 21 and producing an extremely short protein that was unlikely to interact with other proteins. These findings suggest that XLH‐HSCR represents the severe end of the XLH spectrum, rather than a neomorphic mutation. A thorough abdominal investigation to rule out HSCR should be considered in patients with XLH accompanied by severe constipation. © 2012 Wiley Periodicals, Inc.
Association of Catechol‐O‐methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population
Authors: Li Wen Jun , Kou Chang Gui , Yu Yaqin , Sun Shilong , Zhang Xuan , Kosten Thomas R. , Zhang Xiang Yang 
Published: February 2012

AbstractThe gene encoding Catechol‐O‐methyltransferase (COMT), a dopamine catabolic enzyme, has been associated inconsistently with schizophrenia in spite of consistent evidence for dopaminergic dysfunction in the prefrontal cortex (PFC) of schizophrenia. Since one contribution to this inconsistency might be genetic heterogeneity, this study investigated whether the COMT gene was associated with the development and symptoms of schizophrenia in relatively genetically homogeneous Chinese schizophrenic patients. We analyzed two polymorphisms (rs740603 and rs4818) of the COMT gene in a case‐control study of 604 Han Chinese (284 patients and 320 controls). The patients' psychopathology was assessed using the Positive and Negative Syndrome Scale (PANSS). We found no significant differences in the rs740603 and rs4818 genotype and allele distributions between the patient and control groups. Quantitative trait analysis by the UNPHASED program showed that the rs740603 and rs740603(G)‐rs4818(G) haplotypes were associated with negative symptoms in the schizophrenic patients, particularly among female patients. Thus, the COMT gene polymorphisms may not contribute to the susceptibility to schizophrenia, but may contribute to the negative symptoms of schizophrenia among Han Chinese. © 2012 Wiley Periodicals, Inc.
Synthesis of bifunctional cellulosic adsorbent by radiation induced graft polymerization of glycidyl methacrylate‐co‐methacrylic acids
Authors: Sokker H. H. , Gad Y. H. , Ismail S. A. 
Published: February 2012

AbstractA bifunctional cotton fabric waste bearing N+ (CH2CH3)3 and COOH groups was prepared by radiation induced graft polymerization of glycidyl methacrylate and methacrylic acid using gamma irradiation and subsequent chemical modification of the grafted cotton fabric with triethylamine. Factors affecting the grafting of cotton fabric such as radiation dose and comonomer composition were investigated. The adsorbent was characterized by Fourier transform infrared spectroscopy and scanning electron microscope. Functional groups were tested for its potential application in the removal of cobalt (Co2+) and nitrate (NO) from aqueous solutions. Batch experiments were performed to evaluate the adsorption efficiency of the modified grafted cellulose (MGC) towards the cation and the anion. The adsorption capacity for Co2+ at pH 3 and pH 5 was 36.0 and 38.5 mg/g, respectively, whereas that of nitrate was 11 mg/g at pH 4.5. The adsorption process of Co2+ and nitrate obeys both Freundlich and Langmuir isotherm models and followed Pseudosecond order kinetics. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Polymer–copper‐modified MWNTs by radiation‐induced graft polymerization and their efficient adsorption of odorous gases
Authors: Kim Kyo‐Il , Oh Sang‐Hyeb , Kwen Hai‐Doo , Choi Seong‐Ho 
Published: February 2012

AbstractPolymer–copper‐modified multi‐walled carbon nanotubes (MWNTs) were prepared by radiation‐induced graft polymerization of epoxy‐containing glycidyl methacrylate and subsequent amination and Cu complexing. Two amines, triethyldiamine and imidazol, were used as polymeric ligand compounds. The Cu‐modified MWNTs were confirmed by high‐resolution transmittance electron microscopy, scanning electron microscopy, X‐ray photoelectron spectroscopy, and thermal gravimetric analysis. The dynamic adsorption of odor gases, such as CH3SH and H2S, on the Cu‐modified MWNTs and amine‐modified MWNTs was also evaluated. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Synergistic antimicrobial effects of polyaniline combined with silver nanoparticles
Authors: Jia Qingming , Shan Shaoyun , Jiang Lihong , Wang Yaming , Li Dan 
Published: February 2012

AbstractSilver/polyaniline nanocomposites (Ag NPs/PANI) containing PANI nanofiber and Ag nanoparticles were synthesized by one‐step approach without using any extra reducing agent or surfactant and applied to new antimicrobial agents. Morphologies and crystallinity of the nanocomposites were characterized with SEM and XRD. The results showed that the average diameter of the PANI nanofibers is around 50–150 nm, and the average particle size of Ag NPs is around 100 nm. The crystallinity of PANI gets better with increasing silver nitride concentration. UV–vis absorption spectroscopy analysis indicated that the Ag NPs have some effect on the microstructure of PANI. The antimicrobial properties of Ag NPs/PANI against Gram‐negative Escherichia coli, Gram‐positive Staphylococcus aureus and fungous Yeast were evaluated using viable cell counts. The test results demonstrated that Ag NPs/PANI have enhanced antimicrobial efficacy compared to that of pure Ag NPs or pure PANI under the same test condition. The mechanism of the synergistic antimicrobial effect of Ag NPs with PANI was also proposed. In addition, thermal gravity analysis indicated that pure PANI and Ag NPs/PANI exhibit better thermal stability. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012