bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of The Effectiveness of Fones and Modified Bass Teeth Brushing Methods on Reducing Plaque Index in Autism Spectrum Disorders Children Aged 6-12 Years
Authors: Shafira Nabilah , Prasasti Annisa Widya , Octavia Alfini 
Published: April 2024

Children with special needs, such as Autism Spectrum Disorders (ASD), are at a higher risk of developing caries. Brushing teeth is the most effective preventive measure to avoid the risk of developing dental and oral diseases. The Fones teeth brushing method has been proven to reduce dental plaque in ASD patients due to its simplicity. The modified Bass method is also reported to be effective in removing interdental plaque. This study is to investigate whether there is a difference in the effectiveness of teeth brushing techniques, specifically the Fones method and the modified Bass method, in reducing the plaque index in children with ASD. A quasi-experimental study with a pre-test and post-test design was conducted, with 24 ASD participants aged between 6-12 years. The Loe and Silness Plaque Index was used to measure the plaque index. Data analysis was conducted by comparing the two methods using a Paired t-test and a one-way ANOVA test. Indicate that there is a significant difference between the two treatments with a significance value of 0.039 (P<0.05). The average plaque index from the Fones method was found to be 0.444 greater than the modified Bass method. In conclusion: There is a difference in effectiveness between the Fones teeth brushing method and the modified Bass teeth brushing method in reducing the plaque index in children with ASD aged 6-12 years.
PRISÃO DO CASAMENTO: LEITURA COMPARADA ENTRE A CLITEMNESTRA, DE ÉSQUILO, E A EMMA BOVARY, DE FLAUBERT
Authors: Irigaray Tiago 
Published: April 2024

Resumo: a despeito dos mais de 2000 anos transcorridos entre as duas narrativas, Clitemnestra e Emma Bovary experienciam muitas dores e agruras em comum, a maior parte delas por causa da instituição do casamento e sua configuração patriarcal. Os paralelos são marcantes e atravessam não apenas o tempo, mas também a barreira dos gêneros literários (o gênero trágico da Grécia Antiga e o Realismo do século XIX), embora o Realismo, esse gênero sério burguês, carregue uma herança trágica que o faça apropriado para questionar instituições sociais, como a tragédia também questionava, embora de forma difusa, intuitiva e errática porque a tragédia grega aconteceu em moldes pré-Iluministas e possui uma estrutura conflituosa única na literatura antiga. O insólito paralelo entre Clitemnestra e Bovary revela muito sobre o que permaneceu arraigado na instituição do casamento e também na literatura.
KEY SUCCESS FACTORS OF SCHOOL LEADERSHIPS IN IMPLEMENTING PROFESSIONAL LEARNING COMMUNITY: A SYSTEMATIC LITERATURE REVIEW
Authors: Siwy Vanessa Elizabeth , Meilani Yohana Cahya Palupi 
Published: April 2024

<p>The study systematically reviews the literature to understand the key success factors for school leadership in fostering PLCs and the most effective leadership style for this endeavor. Through a detailed analysis, it identifies key success factors such as visionary leadership, shared values, effective communication, collaborative decision-making, and strategic problem-solving. The study also emphasized the transformative, facilitative, distributed, democratic, and situational leadership styles conducive to PLC success.. These elements are essential for creating a collaborative learning environment that promotes professional growth, innovation, and improved student outcomes. The study acknowledges limitations including the scope of literature and challenges in directly correlating leadership styles with PLC success. Future research directions include exploring the long-term impact of leadership on PLCs, cross-contextual comparisons, empirical validations of theoretical frameworks, and the role of digital technologies in PLC enhancement.</p><p> </p>
PERUBAHAN FONETIS BAHASA JAWA STANDAR DIALEK JEMBER
Authors: Fitriah Siti 
Published: April 2024

Bahasa Jemberan atau bahasa Jawa dialek Jember merupakan bahasa Jawa yang memiliki kekhasan di antara dialek bahasa Jawa. Hal itu terjadi karena Jember merupakan salah satu tempat bertemunya dua etnis besar yang ada di Indonesia, yaitu suku Jawa dan suku Madura yang menghasilkan budaya baru yang dikenal dengan budaya pendalungan. Interaksi antaretnis memungkinkan terjadinya perubahan fonetis pada kosakata bahasa Jawa pada tuturan masyarakat Jember. Tujuan penelitian ini adalah untuk mendeskripsikan bentuk perubahan fonetis bahasa Jawa standar dialek Jember dan penyebab perubahan tersebut terjadi. Metode yang digunakan adalah metode komparatif deskriptif yakni dengan mendeskripsikan perbandingan unsur fonetis yang ada di dalam bahasa Jawa standar dengan bahasa Jawa dialek Jember. Data dikumpulkan dengan menggunakan teknik refleksif-introspektif. Hasil analisis data menunjukkan bahwa terdapat lima fonem di dalam bahasa Jawa standar yang mengalami perubahan bunyi ketika dilafalkan pada kosakata tertentu, yaitu fonem /o/, /i/, /u/, /w/, dan /p/. Penyebab perubahan fonetis tersebut diakibatkan oleh asimilasi fonemis, asimilasi bukan fonemis, dan kontraksi.
ANALISIS WACANA KRITIS MODEL TEUN A. VAN DIJK PADA NASKAH FILM PULAU PLASTIK
Authors: Astari Delima , Widayati Dwi , Siregar Asrul 
Published: April 2024

<p><span>Tujuan penelitian ini adalah untuk mengkaji unsur teks, kognisi sosial, dan konteks sosial pada naskah film Pulau Plastik. Penelitian ini dilakukan dengan pendekatan analisis wacana kritis model van Dijk. Yang menjadi sumber data adalah nasakah film Pulau Plastik. Pengumpulan data yang dilakukan dengan teknik simak dan catat. Untuk menganalisis data digunakan metode agih berupa teknik dasar dan teknik lanjutan. Hasil penelitian ini sebagai berikut. Pertama, dari analisis struktur teks ditemukan tiga aspek, yaitu (1) pada struktur makro, tema film adalah bahaya penggunaan sampah plastik sekali pakai; (2) pada unsur superstruktur ditemukan judul dan lead menampilkan situasi dan komentar yang saling berkaitan; (3) pada struktur mikro, dalam film terkandung elemen latar, detail, maksud, pranggapan, bentuk kalimat, kata ganti, preposisi, konjungsi, leksikon, gaya bahasa. Kedua, kognisi sosial yang dipresentasikan dalam film Pulau Plastik adalah keadaan pribadi para tokoh mengenai darurat sampah, penilaian orang terhadap peristiwa tersebut, serta bagaimana tokoh memahami peristiwa di sekitarnya. Ketiga, pada konteks sosial ditemukan bahwa praktik kekuasaan yang dilakukan pemerintah hanya memberi dukungan tanpa memberi solusi yang baik terhadap darurat sampah. Hasil penelitian ini dapat membuka mata terhadap peristiwa darurat sampah di Indonesia yang selama ini diacuhkan begitu saja.</span></p>
NILAI SOSIAL DAN FUNGSI SAGE KISAH SITI FATIMAH BINTI MAIMUN DI GRESIK DALAM KEHIDUPAN BERMASYARAKAT: TEORI FUNGSI BASCOM
Authors: Gita Tiara Ayu Berliana Ana 
Published: April 2024

<p class="AbstrakKataKunci"><span class="s6">Seperti daerah lainnya, Gresik memiliki tradisi lisan yang hampir punah karena belum didokumentasikan sehingga tidak diketahui keberadaannya oleh masyarakat setempat, terutama generasi muda. Tujuan penelitian ini adalah untuk </span><span class="s6">mempresentasikan nilai, fungsi, dan implementasi </span><span class="s6">sage</span><span class="s6"> Siti Fatimah</span><span class="s6"> </span><span class="s6">binti Maimun </span><span class="s6">di Gresik</span><span class="s6"> yang masih bersifat tradisi lisan</span><span class="s6">. </span><span class="s6">Penelitian ini dilakukan dengan</span><span class="s6"> metode deskriptif kualitatif</span><span class="s6"> yang menganalisis cerita berupa sage Siti Fatiman dengan teoti fungsi Bascom</span><span class="s6">. Yang informan kuncinya adalah warga lokal di Desa</span><span class="s6"> Leran</span><span class="s6"> yang memahami kisah Siti Fatimah dan pemilihannya dilakukan dengan </span><span class="s13">purposive sampling</span><span class="s6"> dan </span><span class="s13">snow ball sampling</span><span class="s6">.</span><span class="s6"> </span><span class="s6">Data dikumpulkan melalui wawancara mendalam yang validitasnya diuji</span><span class="s6"> melalui triangulasi metode dan triangulasi sumber. Analisis yang dilakukan berupa identifikasi data, klasifikasi data, tafsiran data, serta kesimpulan data. </span><span class="s6">Hasil penelitian ini menunjukkan </span><span class="s6">nilai sosial</span><span class="s6"> dalam sage Siti Fatimah</span><span class="s6"> </span><span class="s6">binti Maimun terletak pada </span><span class="s6">karakter positif</span><span class="s6"> yang dimiliki Nyai siti</span><span class="s6"> serta implementasi sikap dari Nyai Siti wajib diteladani oleh masyarakat karena mengandung banyak nilai moral, sosial, dan agama</span><span class="s6">. Adapun fungsi sage Siti Fatimah </span><span class="s6">adalah </span><span class="s6">(</span><span class="s6">1) s</span><span class="s6">ebagai a</span><span class="s6">lat hiburan</span><span class="s6"> karena </span><span class="s6">kisahnya dapat dijadikan sebagai penarik perhatian bagi pendengar,</span><span class="s6"> (</span><span class="s6">2</span><span class="s6">) sebagai alat pengesahan pranata dan lembaga kebudayaan </span><span class="s6">dalam rangka m</span><span class="s6">enjaga sikap sosial masyarakat, </span><span class="s6">(</span><span class="s6">3</span><span class="s6">) sebagai alat pendidikan, digunakan untuk mengoreksi diri setiap harinya, dan </span><span class="s6">(</span><span class="s6">4</span><span class="s6">) sebagai alat pemaksa dan pengawas digunakan sebagai penetapan tanggal peringatan haul di masyarakat Gresik dan sekitarnya.</span></p>
Flowback Rates for Pump-In/Flowback Test
Authors: Wang Rui , Dahi Taleghani Arash , Cai Yuzhe 
Published: April 2024

Summary
The pump-in/flowback test (PIFT), often referred to as the diagnostic fracture injection test (DFIT) with flowback, offers notable advantages in terms of time efficiency and accuracy, particularly in the context of low-permeability formations. The key to the success of this test lies in the careful selection of an optimal flowback rate to yield meaningful results. The fundamental assumption underlying the pressure analysis of these tests is the uniform closure of fractures during the flowback phase, which is considered the default fracture closure mode in current analyses. In this study, we present evidence that challenges the validity of this assumption, highlighting instances where unsuitable flowback rates can lead to nonuniform fracture closure and result in abnormal pressure data. To address this challenge, we identify different closure modes through the signature of fracture closure in the excessive bottomhole pressure decline curve. Subsequently, we propose an optimal range of flowback rates using a scaling analysis approach to obtain a uniform closure mode in an extended openhole section of a vertical well. Our method has been rigorously validated through 3D numerical simulations and field studies, enhancing its reliability and applicability. This approach helps operators to conduct effective tests in complex situations, overcoming a barrier to widespread test application.
Experimental Study on Low-Temperature-Oxidation Parameters and Simulations of Exothermic Process during Air Injection in Light Oil Reservoirs
Authors: He Wangrong , He Houfeng , Zheng Haoran , Liu Pengcheng 
Published: April 2024

Summary
The thermal development process for light oil reservoirs using air injection technology is to release heat through low-temperature oxidation (LTO) between the injected air and crude oil and gradually increase the reaction zone’s temperature to displace crude oil. However, existing LTO experimental methods for air injection do not adequately capture the characteristics of LTO and struggle to directly obtain LTO kinetic parameters at low temperatures. In this paper, we used light oil samples from the Huabei Oilfield, China, as the studied objects and proposed innovative methods for obtaining and calculating LTO kinetic parameters. Further, we validated the feasibility of the proposed methods through experimental and numerical simulations. The results indicate that the lower limit temperature at which oxidation parameters can be directly measured through the accelerating rate calorimeter (ARC) experiments is 124°C. We matched the calculations from the ARC experiment curve-extension method for kinetic parameters with the results from both the high-pressure thermogravimetric analyzers (HP-TGA) experiment and the ramped thermal oxidizer (RTO) experiment. The fit between these results indicates that three methods are suitable for obtaining LTO parameters and can be used to derive chemical equations for LTO reactions in numerical simulation models. The simulation results from the reservoir scale indicate that, following air injection into the light oil reservoir, the peak temperature at the leading edge of the high-temperature zone reaches 370.9°C. The interaction between crude oil and air remains in the LTO phase, facilitating a sustained thermal accumulation within the reservoir. This study can provide a reference for reservoir development under similar conditions.
Mentorship Matters”: A Comprehensive Exploration of Student Perspectives in Medical and Dental Training
Authors: Ali Sara , Ganji Kiran Kumar , Shabbir Muhammad , Bandy Altaf , Darraj Ali Qassim , Khattak Osama , Iqbal Azhar , memon Muhammad Rizwan , Sultan Sherif El Sayed 
Published: April 2024

Abstract

Background & Objective: Mentoring, a time-honoured practice dating back to ancient Greece, has gained renewed significance in educational settings. This study explores the perceptions of medical and dental students in mentoring programs, emphasizing the importance of mentoring for academic growth, career development, and personal improvement.
Materials & Methods: A comparative cross-sectional study was conducted in a medical and dental colleges of Pakistan & Egypt, utilizing a questionnaire-based survey with Likert Scale responses. Participants included 306 students, with data collected through convenience sampling. Demographic data and mentoring program perceptions were assessed. Two themes: Mentorship Satisfaction and Support and Impact of Mentoring on Professional and Personal Development were linked to the questionnaire to assess their impact on student perception. Data was analysed using
Results: Analysis revealed a diverse participant distribution across gender, program type, and academic levels. Ordinal logistic regression identified significant factors influencing mentorship satisfaction and support. Fourth-year students exhibited higher satisfaction odds, while negative impacts on professional and personal development decreased satisfaction odds. Positive perceptions of navigating the mentorship compass significantly increased satisfaction odds. Ordinal logistic regression analysis was performed to asses the impact student perception with mentorship.
Conclusion: Tailored mentorship programs, acknowledges the nuanced impact on students' satisfaction, professional development, and personal growth. As a two-way process, effective mentorship fosters a collaborative environment, positively influencing both mentors and mentees. Understanding these dynamics is crucial for optimizing mentoring relationships and promoting successful academic and professional journeys.
A cavotricuspid isthmus dependent flutter with an unexpected left atrial activation sequence: A case report
Authors: Tabbah Randa , Abi-Saleh Bernard 
Published: April 2024

Abstract

Introduction: The isthmus-dependent right atrial flutter is a known arrhythmia, but few studies described the sequence activation of the left atrium. It is well established that the interatrial connection occurs through different pathways: the coronary sinus (CS), the Bachmann's bundle and the fossa ovalis. We describe a case of a cavotricuspid isthmus-dependent right atrial flutter with an unexpected left atrial activation sequence. Case presentation: A 47-year-old female with scleroderma and a history of isolated right ventricular cardiomyopathy had recurrent atrial flutter episodes despite medical therapy. The patient was still symptomatic despite full medical therapy. She presented to the electrophysiology (EP) laboratory for mapping and ablation of atrial flutter with 2:1 and 3:1 conduction. A decapolar deflectable CS catheter placed in the coronary sinus showed a distal to proximal CS activation with a flutter cycle length of 240 msec. Then, the Cavo Tricuspid Isthmus (CTI) demonstrated a concealed entrainment with a post-pacing interval (PPI) almost equal to the total cycle length (TCL) confirming the diagnosis of an isthmus-dependent flutter. The CS activation in sinus rhythm also showed a distal to proximal activation. This confirmed that the CS and the left atrium (LA) are being activated most probably through the Bachman bundle anteriorly and superiorly. CTI line was performed under intracardiac echo (ICE) guidance. Clinical improvement was noticed. A distal to proximal CS activation doesn’t exclude a right atrial arrhythmia. Conclusion: A systemic entrainment mapping of both the right and left atrium is crucial to prevent unneeded transseptal puncture.
Exploration of the Immune-related Gene Set Score (IRGS) in the Prognosis and Immunotherapy of Lung Adenocarcinoma (LUAD)
Authors: Li Dongfang , Xie Yuancai , Yan Jun , Wu Mengxi , Zhang Jianhua , Liu Jixian 
Published: April 2024

Abstract

Background: With the rapid development of immunotherapy for solid tumors, the exploration of immune characteristics becomes more and more important. Due to the high morbidity and mortality of LUAD in Chinese population, it is of great significance to explore its immune characteristics.
Methods: Eight GEO cohorts were used to screen for immune and prognostically relevant genes. An IRGS predictive model was constructed using the ssGSEA algorithm and internally validated. The performance of the model was further verified in five external validation cohorts. To evaluate immune cell infiltration, TIMER, XCELL, and CIBERSORT were applied to quantify the relative proportions of infiltrating immune cells.
Results: Patients with high IRGS exhibited significantly better overall survival (OS) compared to those with low IRGS (HR = 0.56, 95% CI 0.46-0.68, P <0.001) in the training set. The same results were obtained in the validation set (HR = 0.45, 95% CI 0.33-0.6, P <0.001). Further validation in five external cohorts yielded consistent results (GSE31210: P <0.001; GSE68465: P =0.039; Chen_2019: P =0.031; TCGA_LUAD: P =0.002; CPTAC_LUAD: P =0.036). In the tumor microenvironment (TME) analysis, patients with high IRGS had higher levels of T cells, B cells, DC cells, and neutrophils. Immunotherapy cohort analysis in a public cohort showed that patients with high IRGS had better progression-free survival (PFS) after immunotherapy (P=0.013).
Conclusions: Patients with high IRGS demonstrated better prognosis and improved immune efficacy. The IRGS model may possess better predictive performance compared to existing immune and genomic instability markers, indicating its potential value for clinical applications.
Predictors of Spontaneous Abortion Among Women Attending Referral and Specialized Public Hospitals of East Ethiopia, A Case-Control Study
Authors: Amsalu Sewmehon , Kasahun Manaye , Hailu Mickiale , Melkamu Netsanet , Yigezu Muluken , Sintayehu Yitagesu , Tekle Yared 
Published: April 2024

Abstract

Background
Spontaneous abortion is one of the most common complications of early pregnancy, occurring in 15–20% of pregnant women. Every year, an estimated 23 million miscarriages occur worldwide, resulting in 44 pregnancy losses every minute. Consistent findings show that spontaneous abortion has a negative impact on current and consecutive pregnancies. It also has an enormous economic impact. When all of these factors are combined with the idiopathic nature of the problem, identifying predictors of spontaneous abortion will have a significant impact on preventing the problem. However, no studies have been conducted in Ethiopia on this topic. Therefore, this study aims to assess the predictors of spontaneous abortion among women attending referral and specialized public hospitals in Eastern Ethiopia.
Methods
An institutional-based unmatched case-control study design was used. Three hundred seventy-one (371) cases and three hundred seventy-one (371) controls were studied. The data were collected by using an interviewer-administered structured questionnaire. The collected data were entered into Epi data version 4.6 and then exported to SPSS window version 25 for analysis. Bivariate and multivariate analyses were used to determine the associations between each independent variable and the outcome variable. All the variables with a P value ≤ 0.25 in the bivariate analysis were included in the final model of multivariable analysis to control for possible confounders. A P value < 0.05 was considered to indicate a statistically significant association.
Result
The following predictors were significantly associated with spontaneous abortion, intended pregnancy [AOR = 0.443, 95% CI: (0.279, 0.703)], folate intake during the current pregnancy [AOR = 0.067, 95% CI: (0.042, 0.106)], coffee consumption [AOR = 3.699, 95% CI: (2.341, 5.846)], stressful life events [AOR = 7.55, 95% CI: (3.932, 14.496)], and history of spontaneous abortion [AOR = 8.86, 95% CI: (3.197, 24.604)].
Conclusion
This study provides evidence that several predictors are independently associated with spontaneous abortion. Importantly, many of these factors can be modified or prevented through appropriate awareness and education among reproductive-age women. By addressing these risk factors, the incidence of spontaneous abortion can be reduced.
Nicotinamide N-methyltransferase enhances paclitaxel resistance in ovarian clear cell carcinoma
Authors: Kikuchi-Koike Ryoko , Sakamoto Masaru , Sasajima Yuko , Miyagawa Yuko , Uozaki Hiroshi , Umayahara Kenji , Hashimoto Kei , Takahashi Yuko , Takasaki Kazuki , Kihira Chikara , Nishida Haruka , Ichinose Takayuki , Hirano Mana , Hiraike Haruko , Nagasaka Kazunori 
Published: April 2024

Abstract

Background. Growing evidence suggests that nicotinamide N-methyltransferase (NNMT), an S-adenosyl-L-methionine (SAM)-dependent cytosolic enzyme, plays an essential role in cancer progression. Recently, it was reported that NNMT is involved in methylation metabolism and tumorigenesis and is associated with poor prognosis in a number of cancers. It has also been reported that NNMT is overexpressed in the stroma of advanced high-grade serous carcinomas and may contribute to poor survival. The aim of this study was to identify novel biomarkers that predict resistance in paclitaxel-resistant advanced or recurrent ovarian clear cell carcinoma (OCCA) and to evaluate their clinicopathologic significance.
Methods. Four OCCA cell lines (ES-2, KK, OVMANA, and OVTOKO) were divided into paclitaxel high and low sensitivity groups by WST-8 assay and fluorescence-labeled two-dimensional electrophoresis (2D-DIGE) was performed. Protein spots with different expression intensities in each drug-sensitive group were analyzed by mass spectrometry to identify the proteins.
Results. NNMT was detected as a protein molecule upregulated in the paclitaxel-resistant group, and knockdown by NNMT siRNA increased paclitaxel sensitivity in the NNMT-expressing ovarian clear cell carcinoma cell lines OVTOKO and RMG1. Furthermore, in analysis of clinical tissue samples, no deaths were observed in 7 patients with low NNMT expression in the cytoplasm of cancer cells.
Conclusions. High NNMT expression in the cytoplasm of cancer cells is associated with low sensitivity to paclitaxel in OCCA and may have prognostic implications; knockdown of NNMT expression also reduced paclitaxel efficacy. Therefore, targeted therapies that reduce cytoplasmic NNMT expression levels may increase the sensitivity of OCCA to paclitaxel.