bluuebunny/crossref_metadata_2025_split huggingface dataset:
ADVANCES IN TREATMENT OF MOOD DISORDERS
Authors: Shah Asim A. 
Published: May 2024

In the last many decades psychotropics have mostly focused on Serotonin, Norepinephrine, and Dopamine for depression, and dopamine blockers for psychosis. Researchers started working diligently and explored new targets like Glutamate in treating depressive disorder and schizophrenia. The antagonist effect of Ketamine on N-methyl-D-aspartate (NMDA) receptors was investigated, which can result in a faster antidepressant response as compared to conventional treatment . GABA receptors were also explored to develop novel compounds, which resulted in the discovery of brexanalone, a neuroactive steroid-positive allosteric modulator of GABAA approved in March 2019 by the FDA for the treatment of postpartum depression. It is administered as an intravenous infusion over 60 hours and results in a rapid antidepressant response in` postpartum depression lasting for more than one week. Another neuroactive steroid Zuranolone effectively treats postpartum depression and major depressive disorder (MDD) . The antidepressant also modulates neuronal plasticity by enhancing the Brain-derived neurotropic factor BDNF levels.
Holī og Dīvalī – to hindufester
Authors: Fibiger Marianne Qvortrup 
Published: May 2024

English abstract: In this article, I will demonstrate how feasts and festivals serve as effective analytical tools to comprehend the diversity within the Hindu tradition. I will use the two festivals: Holī and Dīvalī as examples. Additionally, I aim to explore whether the historical anchors of a festival, or multiple anchors, have significance for the interpretative potential associated with the festival today. I will particularly focus on whether the festival is strongly or weakly tied to one or more myths and whether it has a tribal/early archaic or archaic origin. I will also investigate if certain festivals within the Hindu tradition seem more adaptable to new contexts outside of India than other.
Dansk resume: I denne artikel vil jeg demonstrere, hvordan fester og festivaler er et godt analyseredskab til at forstå den hinduistiske tradition i sin mangfoldighed, men også til at undersøge, om festens historiske forankringspunkt eller forankringspunkter har betydning for det fortolkningspotentiale, man kan knytte til festen i dag. Her vil jeg særligt tage udgangspunkt i de to fester Holī og Dīvalī. Et analytisk omdrejningspunkt er, om festen knytter sig stærkt eller svagt til en eller flere myter, og om den har et tribalt/tidlig arkaisk eller et arkaisk ophav. Jeg vil også undersøge om visse fester inden for den hinduistiske er mere adaptiv til nye sammenhænge uden for Indien end andre.
Keywords: Holī; Divāli; adaption; mythological strong, mythological weak
Interrelationships of Quality of Parental Relationship, Self-esteem, and Relational Skills among 4Ps Teenage Beneficiaries in Iligan City, Philippines
Authors: Sudaria Rogel Equirne D. , Napiere Miguela B. 
Published: May 2024

Understanding how family dynamics and self-esteem impact the social development of teenagers from low-income backgrounds is crucial for designing effective youth development programs. This study investigates the relationship between parental relationships, self-esteem, and relational skills among senior high school students who are beneficiaries of the Pantawid Pamilyang Pilipino Program (4Ps) in Mindanao, Philippines. Utilizing a descriptive-correlational design and simple random sampling, the study surveyed 171 students using standardized questionnaires. Data analysis included mean, standard deviation, Pearson correlation, and linear regression. Participants reported high parental relationship quality, self-esteem, and relational skills components such as bi-directional communication, disclosure and interpersonal closeness, and emotional experience and expression. However, assertion and conflict resolution skills were rated moderately. Parental relationships significantly correlated with self-esteem, particularly with mothers (p<0.05). Both factors significantly influenced relational skills (p<0.05). These findings suggest that while the 4Ps program may positively impact family relationships and self-esteem, additional support might be beneficial for developing stronger assertion and conflict resolution skills among beneficiaries, potentially leading to improved overall social development.
The Influence of Anti-scatter Grid Usage for Knee Computerized Radiography
Authors: Cassol Luísa Vargas , Favarin Nataly Nogueira , Bail Felipe de , Buss Edméia Lopes Ramai , Nogueira Laura Pizarro Trojahn , Rosa Jéssica Fetzer da Costa , Claus Thiago Victorino 
Published: May 2024

Aims: This experimental study investigated the effect of using an anti-scatter grid in computerized knee radiography (CR) on image quality (IQ) and patient surface radiation dose (Equivalent Surface Air Kerma – Ka,e), measured with an ionization chamber.
Place and Duration of Study: The experimental study was conducted between February 2024 and April 2024, in the radiodiagnosis laboratory belonging to the Medical Physics and Radiology Technology courses at the Franciscan University (UFN) in the city of Santa Maria, Rio Grande do Sul.
Methodology: Utilizing a semi-anatomical knee phantom to simulate clinical examination conditions, ten images were acquired, with five obtained using technique 1 (70 kV, 200mA, and 20mAs) and another five with technique 2 (70 kVp, 200mA, and 5 mAs), with and without an anti-scatter grid, respectively. The phantom images were digitized in a CR system and quantified using a publicly available automatic analyzer software based on histograms and regions of interest (ROI), defined by signal and noise. The obtained results were used to calculate the signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and radiographic contrast (RC), considered IQ descriptors.
Results: As a selection criterion, the percentage deviation (D%) was chosen, considering technique 1 as the reference concerning technique 2. It was observed that technique 1 showed an SNR 1.20%, RC 3.86%, and Ka,e 73.68% higher than technique 2; on the other hand, technique 2 indicated a CNR 4.76% higher compared to technique 1.
Conclusion: It is concluded that technique 2 without an anti-scatter grid may be preferable when considering the principle of optimization, where the dose is significantly reduced without a significant loss in IQ descriptors.
Physicochemical Characteristics of Titania Particles Synthesized with Gelatin as a Template Before and After Regeneration and Their Performance in Photocatalytic Methylene Blue
Authors: Ulfa Maria , Pangestuti Indriyani , Anggreani Cindy Nur 
Published: May 2024

TiO2 material has an important position in the processing of methylene blue waste because it is economical, has abundant polymorphs, high sustainability and supports green chemistry applications. Mesoporous TiO2 is a porous material that has higher effectiveness than other TiO2 because the pore structure has a large diameter at the nano scale (2-50 nm) with a regular shape so that the surface area and pore volume are greater than the average for other TiO2. The synthesis of mesopore TiO2 material has so far used the sol-gel route with synthetic pore directing agents such as P123 which can be replaced with gelatin as a cheaper and safer pore directing agent with high sustainability and abundance. Based on the description above, this research aims to photodegrade methylene blue using mesoporous TiO2 (m-TiO2) nanoparticles which were prepared by the sol–gel method using gelatin and P123 as template. X-ray diffraction (XRD), scanning electron microscopy (SEM), Electron dispersive X-Ray (EDX), and UV–vis spectroscopy techniques were used to characterize the samples. Photocatalytic activities of samples for methylene blue degradation were investigated. The catalyst before and after regeneration will be studied so that the effect of regeneration on the results of methylene blue photocatalysis with m-TiO2 can be determined. XRD results confirmed the formation of the anatase and rutile phase for the TiO2 nanoparticles, with crystallite sizes larger after regeneration in the range of 9–21 nm. The large particle size was after regeneration due to the promotion by high temperature treatment. TiO2 nanoparticles showed the best photocatalytic activity on the first use to 91% and remained stable after four cycles with photodegradation efficiency up to 76% based on the measured UV-Vis spectroscopy. TiO2 as synthesis could be the best candidate for catalyst with the high performance after multicycle regeneration. Copyright © 2024 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Temperature‐Resolved Local and Macroscopic Charge Carrier Transport in Thin P3HT Layers
Authors: Pingel Patrick , Zen Achmad , Abellón Ruben D. , Grozema Ferdinand C. , Siebbeles Laurens D.A. , Neher Dieter 
Published: June 2010

AbstractPrevious investigations of the field‐effect mobility in poly(3‐hexylthiophene) (P3HT) layers revealed a strong dependence on molecular weight (MW), which was shown to be closely related to layer morphology. Here, charge carrier mobilities of two P3HT MW fractions (medium‐MW:Mn = 7 200 g mol−1; high‐MW:Mn = 27 000 g mol−1) are probed as a function of temperature at a local and a macroscopic length scale, using pulse‐radiolysis time‐resolved microwave conductivity (PR‐TRMC) and organic field‐effect transistor measurements, respectively. In contrast to the macroscopic transport properties, the local intra‐grain mobility depends only weakly on MW (being in the order of 10−2cm2V−1s−1) and being thermally activated below the melting temperature for both fractions. The striking differences of charge transport at both length scales are related to the heterogeneity of the layer morphology. The quantitative analysis of temperature‐dependent UV/Vis absorption spectra according to a model of F. C. Spano reveals that a substantial amount of disordered material is present in these P3HT layers. Moreover, the analysis predicts that aggregates in medium‐MW P3HT undergo a “pre‐melting” significantly below the actual melting temperature. The results suggest that macroscopic charge transport in samples of short‐chain P3HT is strongly inhibited by the presence of disordered domains, while in high‐MW P3HT the low‐mobility disordered zones are bridged via inter‐crystalline molecular connections.
Magnetically Controllable Silver Nanocomposite with Multifunctional Phosphotriazine Matrix and High Antimicrobial Activity
Authors: Dallas Panagiotis , Tucek Jiri , Jancik Dalibor , Kolar Milan , Panacek Ales , Zboril Radek 
Published: June 2010

AbstractA recently developed multi‐functional phosphotriazine‐based polymer is used as a matrix for embedding γ‐Fe2O3 nanoparticles as well as a suitable chemical template for surface modification with silver nanoparticles. For the primary magnetic modification, maghemite nanoparticles are surface modified with oleic acid in order to render them organophilic and to prevent the aggregation of the nanoparticles. This aggregation could occur as the polymer synthesis, based on reaction of phosphonitrilic chlorine and 1,4‐phenylenediamine, takes place in toluene. The surface active amine units of the polymer structure enable the reduction of silver cations to silver nanoparticles, which are well attached and finely dispersed on its surface. The developed nanocomposite represents one of the few magnetically controllable antibacterial agents based on silver nanoparticles. Magnetic measurements reveal the completely suppressed interactions among maghemite nanoparticles because of their perfect surface coating with an organic surfactant and fine dispersion inside the polymer matrix. This magnetic nanocomposite exhibits a high antibacterial and antifungal activity as proven by tests with nine bacterial strains and four candida (yeast genus) species. For the majority of the tested species, the minimum‐inhibition concentrations are below 100 mg L−1, which is comparable to their equivalent minimum‐inhibition concentrations in colloidal silver systems.
Patterned Hydrogels for Controlled Platelet Adhesion from Whole Blood and Plasma
Authors: Ekblad Tobias , Faxälv Lars , Andersson Olof , Wallmark Nanny , Larsson Andréas , Lindahl Tomas L. , Liedberg Bo 
Published: June 2010

AbstractThis work describes the preparation and properties of hydrogel surface chemistries enabling controlled and well‐defined cell adhesion. The hydrogels may be prepared directly on plastic substrates, such as polystyrene slides or dishes, using a quick and experimentally simple photopolymerization process, compatible with photolithographic and microfluidic patterning methods. The intended application for these materials is as substrates for diagnostic cell adhesion assays, particularly for the analysis of human platelet function. The non‐specific adsorption of fibrinogen, a platelet adhesion promoting protein, is shown to be completely inhibited by the hydrogel, provided that the film thickness is sufficient (>5 nm). This allows the hydrogel to be used as a matrix for presenting selected bioactive ligands without risking interference from non‐specifically adsorbed platelet adhesion factors, even in undiluted whole blood and blood plasma. This concept is demonstrated by preparing patterns of proteins on hydrogel surfaces, resulting in highly controlled platelet adhesion. Further insights into the protein immobilization and platelet adhesion processes are provided by studies using imaging surface plasmon resonance. The hydrogel surfaces used in this work appear to provide an ideal platform for cell adhesion studies of platelets, and potentially also for other cell types.
Effects of food, proximity, and kinship on social behavior in ringtailed lemurs
Authors: Sbeglia Gena C. , Tang‐Martinez Zuleyma , Sussman Robert W. 
Published: June 2010

AbstractEfforts to understand the variation in primate social systems and their underlying interaction patterns have focused on both intrinsic and extrinsic factors. In the socioecological model, food distribution and abundance have been argued to be the primary influences on the social behavior of primate species. We examined the relationship of food resources and two intrinsic factors—kinship and proximity—with patterns of affiliative and agonistic relationships in two semi‐free ranging ringtailed lemur,Lemur catta, social groups (N=14) at The Duke Lemur Center in Durham, NC. In analyzing these three factors concurrently within the same system, we attempt to establish their relative power in explaining the characteristics of social relationships. Patterns of affiliation and high‐intensity agonism were best explained by kinship. Proximity also explained affiliation but did not explain agonism, which varied considerably between groups. The influence of food on social interactions was highly variable between the two groups and, therefore, did not convincingly account for the social behavior patterns we observed. Finally, different intensities of agonism have different patterns and should be analyzed individually. The variation between social groups makes it difficult for us to conclude that any one factor is primarily and universally responsible for patterns of social behavior in this species. Am. J. Primatol. 72:981–991, 2010. © 2010 Wiley‐Liss, Inc.
Purification and properties of trypsin‐like enzyme from the midgut of Morimus funereus (coleoptera, cerambycidae) Larvae
Authors: Lončar Nikola , Vujčić Zoran , Božić Nataša , Ivanović Jelisaveta , Nenadović Vera 
Published: June 2010

AbstractTrypsin‐like enzyme (TLE) from the anterior midgut of Morimus funereus larvae was purified by anion exchange chromatography and gel filtration chromatography and characterized. Specific TLE activity was increased 322‐fold by purification of the crude midgut extract. The purified enzyme had a pH optimum of 9.0 (optimum pH range 8.5–9.5) and temperature optimum of 45°C with the KM ratio of 0.065 mM for benzoyl‐arginine‐p‐nitroanilide (BApNA). Among a number of inhibitors tested, the most efficient was benzamidine (KI value of 0.012 mM, Ic50 value of 0.204 mM) while inhibition of TLE activity by SBTI, TLCK, and PMSF was partial. Almost all divalent cations tested enhanced the enzyme activity, amongst them Co2+ and Mn2+ stimulated TLE activity for 2.5 times. The purified TLE (after gel‐filtration on Superose 12 column) had a molecular mass of 37.5 kDa with an isoelectric point over 9.3. Sodium dodecylsulphate‐polyacrylamide gel electrophoresis (SDS‐PAGE) revealed one band of 38 kDa, suggesting that the enzyme is a monomer. © 2010 Wiley Periodicals, Inc.
Radial artery flow‐mediated dilation predicts arterial spasm during transradial coronary interventions
Authors: Deftereos Spyridon , Giannopoulos Georgios , Kossyvakis Charalampos , Driva Metaxia , Kaoukis Andreas , Raisakis Konstantinos , Theodorakis Andreas , Panagopoulou Vasiliki , Lappos Spyridon , Tampaki Eleni , Pyrgakis Vlasios , Stefanadis Christodoulos 
Published: June 2010

AbstractBackground: Transradial coronary catheterization has emerged over the last years as a favorable catheterization practice, based on evidence that it is associated with less vascular complications and shorter hospital stays. However, access site crossover appears to be more frequent when the initial route is the transradial one, one of the main reasons being arterial spasm. We hypothesized that radial flow‐mediated dilation (FMD) measurements could be used as a preprocedural method to assess the likelihood of arterial spasm. Methods: The study population consisted of patients scheduled for transradial diagnostic catheterization in whom ad hoc percutaneous coronary intervention (PCI) was performed. FMD was measured 1–2 days before PCI. The primary endpoint of the study was operator‐defined (operators were blinded as to the FMD results) radial artery spasm. Results: A total of 172 patients (110 male, age 65.3 ± 9) were included. Radial artery spasm was recorded in 13 patients (7.6%). FMD showed a very significant univariate association with the occurrence of spasm (P < 0.001) and was the most important predictor of spasm in the multivariate logistic regression analysis (beta −3.15; P < 0.001), followed by baseline radial artery diameter (P = 0.04), the number of catheters used (P = 0.049) and the administered volume of contrast medium (P = 0.017). Conclusion: Preprocedural FMD is a significant predictor of arterial spasm before elective transradial PCI. It is a low cost, safe, and feasible noninvasive modality, whose results might be taken into account when deciding on the vascular access route for an elective procedure, the size of sheaths or catheters to be used or the intensity of antispasm medication.© 2010 Wiley‐Liss, Inc.
Synthesis of Fused and Linked Bicyclic Nitrogen Heterocycles by Palladium‐Catalyzed Domino Cyclization of Propargyl Bromides
Authors: Okano Akinori , Tsukamoto Koji , Kosaka Shohei , Maeda Hatsuo , Oishi Shinya , Tanaka Tetsuaki , Fujii Nobutaka , Ohno Hiroaki 
Published: June 2010

AbstractThe palladium(0)‐catalyzed direct construction of bicyclic heterocycles is described. Treatment of propargyl bromides that have nucleophilic functional groups connected by two or three carbon atoms with catalytic [Pd(PPh3)4] affords bis‐cyclization products in good yields. The desired bicyclic heterocycles can be obtained selectively when using substrates with appropriate nucleophilic groups. We also describe the reaction of a 2‐alkynylazetidine derivative with a catalytic amount of [Pd(PPh3)4] under base‐free conditions, which affords the same fused heterocycles as the corresponding propargyl bromides.
Stereocontrolled Synthesis of Spiro[n.2]alkenes by Ring Contraction of Fused‐Cyclobutanols
Authors: Takasu Kiyosei , Nagamoto Yuuki , Takemoto Yoshiji 
Published: June 2010

AbstractAn unusual ring‐contraction rearrangement to give spirocyclopropanes from fused cyclobutanols (see scheme) has been developed. It is found that the strain energy of the substrates derived from an additional fused ring and the stereoelectronic effect of the migrating σ bond are important factors. It is noteworthy that the rearrangement proceeds in a stereospecific manner. Moreover, the method provides a spiro(cyclopropane–indane) framework from tricyclo[6.3.0.02,5]undecane, which corresponds to illudane and the protoilludane skeleton.
ChemInform Abstract: Catalytic Asymmetric Hydrogenation of 1‐Aza‐2‐cycloalkene‐2‐carboxylates Catalyzed by a trans‐Chelating Chiral Diphosphine PhTRAP—Rhodium Complex.
Authors: Kuwano Ryoichi , Karube Daisuke , Ito Yoshihiko 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Experiments Directed Towards the Synthesis of Anthracyclinones. Part 34. Hetero‐Diels—Alder Reactions Using Chiral Boron and Titanium Reagents.
Authors: Bercich Mark D. , Cambie Richard C. , Rutledge Peter S. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reaction of Silyl Enol Ethers with Xenon Difluoride in MeCN: Evidence for a Nonclassical Radical Cation Intermediate.
Authors: Ramsden Christopher A. , Smith Rachel G. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polyoxometalates as Reduction Catalysts: Deoxygenation and Hydrogenation of Carbonyl Compounds.
Authors: Kogan Vladimir , Aizenshtat Zeev , Neumann Ronny 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Activated Sterically Strained C=N Bond in N‐Arylsulfonyl‐p‐quinonimines and Diimines. Part 5. Reaction with Dialkyl Phosphites.
Authors: Avdeenko A. P. , Menafova Yu. V. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aerobic Deprotection of Monothioacetals Catalyzed by Trichlorooxyvanadium.
Authors: Kirihara Masayuki , Ochiai Yuta , Arai Nobuka , Takizawa Shinobu , Momose Takefumi , Nemoto Hideo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Study of the Reaction of Different Phenol Substrates with Nitric Oxide and Peroxynitrite.
Authors: Yenes Susana , Messeguer Angel 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.