bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of edible mushrooms in the Brazilian diet: a comprehensive analysis
Authors: Carvalho Ana Júlia Souto , Zárate-Salazar Jhonatan Rafael , Jacob Michelle Cristine Medeiros , Araújo Patrícia Lima , Gomes Sávio Marcelino , Pereira Fillipe De Oliveira 
Published: April 2024

Purpose
This study aims to examine the role of edible mushrooms in the Brazilian diet, considering their strategic significance in meeting nutritional goals within sustainable development. Despite their potential in the nutrition of the Brazilian population, significant knowledge gaps still exist. To address this, the authors formulated this study into five main sections: the consumption of edible mushrooms in Brazil, the factors influencing the consumption, the occurrence of edible mushrooms in Brazil, the nutritional contribution of mushrooms consumed in Brazil and sustainable mushroom production in Brazil.

Design/methodology/approach
The authors compiled current literature to develop this viewpoint paper using systematic review, systematic search and narrative review search methods.

Findings
Mushrooms are sporadically consumed in Brazil, primarily by the urban population, with challenges in estimating the most used species. Social, economic and cultural factors, health considerations and reduced meat consumption influence mushroom consumption behavior. While Pleurotus ostreatus, Lentinula edodes and Agaricus bisporus are primary species, ethnomycological studies highlight a more diverse consumption among traditional indigenous communities. Brazil hosts approximately 133 wild mushroom species safe for human consumption. Some can be sustainably cultivated using substrates derived from agricultural and urban waste, offering high-protein, high-fiber, low-fat foods with bioactive compounds holding antioxidant and prebiotic potential.

Originality/value
To the best of the authors’ knowledge, no previous study has investigated how edible mushrooms contribute to the food and nutrition of the Brazilian population. This study emphasizes the crucial role of edible mushrooms in preserving Brazil’s cultural heritage, contributing to food and nutritional security and enhancing the overall diet quality.
Service quality assessment in a Greek teacher training program: a cultural perspective
Authors: Athanasiadis Anastasios , Papadopoulou Vassiliki , Tsakiridou Helen , Iordanidis George 
Published: April 2024

Purpose
This paper aims to investigate the relationship between prospective teachers’ cultural profiles and service quality expectations in a pedagogical training program in Greece.

Design/methodology/approach
Using the EppekQual scale and an alternative Hofstede’s cultural scale, 113 prospective teachers in a Greek training program were surveyed. The study uses descriptive statistics, correlation analysis and multiple regression, validating measurements through confirmatory factor analysis.

Findings
Prospective teachers exhibit a low-power orientation and a preference for feminine values. Rejecting hierarchy correlates with quality expectations, especially in the curriculum dimension, emphasizing student-centric education. A positive correlation with acceptance/avoidance of uncertainty is observed, notably in learning outcomes and administrative services. The cultural aversion to ambiguity shapes individuals’ prioritization of all quality dimensions. A realistic long-term perspective correlates positively with expectations in learning outcomes, aligning with Greek culture’s emphasis on security. Contrary to expectations, a predilection for feminine values positively impacts service quality expectations, particularly in curriculum, learning outcomes and academic staff dimensions. The hypothesis related to individualism/collectivism is not substantiated, indicating a negative association with the curriculum dimension.

Practical implications
Tailoring program designs to embrace student-centric and collaborative learning environments is recommended. Acknowledging cultural aversions to uncertainty, program flexibility and clarity are essential. Integrating career planning and mentorship aligns with realistic long-term perspectives. The need for a balanced approach to personal and intellectual development is also suggested.

Originality/value
This study uncovers specific cultural dimensions that shape quality expectations within a Greek teacher training context.
Cutaneous manifestations of adult‐onset Still's disease: A comparative study between young‐onset and elderly‐onset groups
Authors: Sato Mayu , Yamamoto Toshiyuki 
Published: April 2024

AbstractWe investigated the detailed characteristics and proportions of typical and atypical rashes in 28 patients with adult‐onset Still's disease (AOSD) by retrospectively examining the clinical symptoms and pathological features. The patients consisted of six males and 22 females aged between 23 and 85 years. The skin rashes observed in the study population were as follows: (i) typical rash in six cases, (ii) atypical rash in 19, and (iii) both typical and atypical rash in three cases (in all three cases, typical rash preceded atypical rash). Furthermore, we classified atypical rashes into persistent pruritic papules and plaques (PPPP) and others. In 22 cases of atypical rashes, 10 cases had PPPP. In a comparison between young‐onset (<65 years) (n = 16) and elderly‐onset (≥65 years) (n = 12) AOSD cases, typical rashes were observed more frequently in the young‐onset cases. Regarding atypical rashes, PPPP was significantly more common in the elderly‐onset cases.
Looking at the bid picture: A framework for identifying reverse auctions in ecological systems
Authors: Fowler Katherine J. , Potratz Emily J. , Malone Margaret , Halloway Abdel , Peplinski Joy , Brown Joel S. 
Published: April 2024

Abstract

Biological market theory can be used to explain intraspecific cooperation, interspecific mutualism, and sexual selection through models of game theory. These models describe the interactions between organisms as two classes of traders (buyers/sellers) exchanging commodities in the form of goods (e.g. food, shelter, matings) and services (e.g. warning calls, protection). Here, we expand biological market theory to include auction theory where bidding serves to match buyers and sellers.

In a reverse auction, the seller increases the value of the item or decreases the cost until a buyer steps forward. We provide several examples of ecological systems that may have reverse auctions as underlying mechanisms to form mutualistic relationships.

We focus on the yellow baboon (Papio cynocephalus) mating system as a case study to propose how the mechanisms of a reverse auction, which have the unintended but emergent consequence of producing a mutually beneficial outcome that improves collective reproductive benefits of the troop in this multi‐female multi‐male polygynandrous social system. For the yellow baboon, we posit that the “seller” is the reproductively cycling female, and the “buyer” is a male looking to mate with a cycling female. To the male, the “item for the sale” is the opportunity to sire an offspring, the price is providing safety and foraging time (via consortship) to the female. The “increasing value of the item for sale” is the chance of conception, which increases with each cycle since a female has resumed cycling post‐partum. The female's sexual swelling is an honest indicator of that cycle's probability of conception, and since resident males can track a female's cycle since resumption, there is transparency. The males presumably know the chance of conception when choosing to bid by offering consortship.

Across nature, this reverse auction game likely exists in other inter‐ and intraspecific social relationships. Considering an ecological system as a reverse auction broadens our view of social evolution and adaptations through the lens of human economic structures.
Design principles for multi‐species productive grasslands: Quantifying effects of diversity beyond richness
Authors: Finn John A. , Suter Matthias , Vishwakarma Rishabh , Oram Natalie J. , Lüscher Andreas , Brophy Caroline 
Published: April 2024

Abstract

Productive grasslands in temperate regions have relied strongly on low plant diversity with high management intensity and fertiliser inputs. Increasing plant diversity can provide high yields of digestible forage for livestock production with lower environmental impacts, and thus represents a diversity‐dependent nature‐based solution that can deliver multiple ecosystem functions.

Sharing lessons from the design of managed, productive grassland communities, we address the following questions: how can we identify combinations of plant species that best deliver a selected function or multiple functions? and; when is community composition more important than species richness?

We describe approaches that separate plant diversity into its underlying components: species richness, composition and relative abundance. Disentangling these three components facilitates a more nuanced understanding of how diversity can contribute to the design of diversity‐dependent nature‐based solutions.
Overview of the distinctive characteristics of strawberry, raspberry, and blueberry in berries, berry wines, and berry spirits
Authors: Bezerra Mário , Ribeiro Miguel , Cosme Fernanda , Nunes Fernando M. 
Published: April 2024

AbstractRed berries have gained popularity as functional and nutritious food due to their health benefits, leading to increased consumer demand and higher production, totaling over 11,000 ktons for strawberries, raspberries, and blueberries combined in 2021. Nutritionally, strawberries, raspberries, and blueberries present high levels of vitamin C (9.7–58.8 mg/100 g dry weight [dw]), folates (6–24 µg/100 g dw), and minerals (96–228 mg/100 g dw). Due to their perishable nature, producers have utilized alcoholic fermentation to extend their shelf life, not only increasing the lifespan of red berries but also attracting consumers through the production of novel beverages. Strawberry, blueberry, and raspberry wines possess low alcohol (5.5–11.1% v/v), high acidity (3.2–17.6 g/L), and interesting bioactive molecules such as phenolic compounds, carotenoids, polysaccharides, and melatonin. Distillation holds tremendous potential for reducing food waste by creating red berry spirits of exceptional quality. Although research on red berry spirits is still in the early stages, future studies should focus on their production and characterization. By incorporating these factors, the production chain would become more sustainable, profitable, and efficient by reducing food waste, capitalizing on consumer acceptance, and leveraging the natural health‐promoting characteristics of these products. Therefore, this review aims to provide a comprehensive overview of the characteristics of strawberry, blueberry, and red raspberry in berries, wines, and spirits, with a focus on their chemical composition and production methods.
COVID‐19’s effects on sense of place and pro‐environmental behaviour
Authors: Li Guangzhen , Evensen Darrick , Stedman Rich 
Published: April 2024

AbstractCOVID‐19 substantially disrupted daily life globally. Human geography and environmental psychology scholars have argued that dramatic shifts in how people used urban environments during the pandemic could have important implications for those studying human–environment relationships and for planners designing urban spaces. Nevertheless, empirical data that examine shifts in human–environment relationships in urban areas during the pandemic are still limited. We explored how COVID‐19 influenced sense of place and investigated how sense of place and changes to daily life because of the pandemic affected environmentally friendly behaviours. A case study involved working with 10 interview participants and 302 survey respondents in Wuhan, China—the city where the pandemic started, and which experienced very strict lockdowns. Data collection occurred in June 2021. The results reveal three main findings. First, stronger emotions directed towards the pandemic and heightened pandemic responses positively affected sense of place, with response behaviours including taking disease prevention measures, spending more time with families/friends, and helping others during the crisis. Second, sense of place and behavioural response to the pandemic were both associated with environmentally friendly behaviours, but not with environmentally friendly attitudes. Third, the nation and city, rather than the community level, are the geographic scales most consonant with respondent notions of place; sense of place grew most at these scales during the pandemic. We conclude that contrary to some speculation, sense of place was enhanced during the pandemic, at least in Wuhan. The pandemic also provided an opportunity for behaviour transitions, but not necessarily via changes in sense of place.
Unravelling the role of the group 6 soluble di‐iron monooxygenase (SDIMO) SmoABCD in alkane metabolism and chlorinated alkane degradation
Authors: Ferrari Eleonora , Di Benedetto Giulio , Firrincieli Andrea , Presentato Alessandro , Frascari Dario , Cappelletti Martina 
Published: April 2024

AbstractSoluble di‐iron monooxygenases (SDIMOs) are multi‐component enzymes catalysing the oxidation of various substrates. These enzymes are characterized by high sequence and functional diversity that is still not well understood despite their key role in biotechnological processes including contaminant biodegradation. In this study, we analysed a mutant of Rhodoccocus aetherivorans BCP1 (BCP1‐2.10) characterized by a transposon insertion in the gene smoA encoding the alpha subunit of the plasmid‐located SDIMO SmoABCD. The mutant BCP1‐2.10 showed a reduced capacity to grow on propane, lost the ability to grow on butane, pentane and n‐hexane and was heavily impaired in the capacity to degrade chloroform and trichloroethane. The expression of the additional SDIMO prmABCD in BCP1‐2.10 probably allowed the mutant to partially grow on propane and to degrade it, to some extent, together with the other short‐chain n‐alkanes. The complementation of the mutant, conducted by introducing smoABCD in the genome as a single copy under a constitutive promoter or within a plasmid under a thiostreptone‐inducible promoter, allowed the recovery of the alkanotrophic phenotype as well as the capacity to degrade chlorinated n‐alkanes. The heterologous expression of smoABCD allowed a non‐alkanotrophic Rhodococcus strain to grow on pentane and n‐hexane when the gene cluster was introduced together with the downstream genes encoding alcohol and aldehyde dehydrogenases and a GroEL chaperon. BCP1 smoA gene was shown to belong to the group 6 SDIMOs, which is a rare group of monooxygenases mostly present in Mycobacterium genus and in a few Rhodococcus strains. SmoABCD originally evolved in Mycobacterium and was then acquired by Rhodococcus through horizontal gene transfer events. This work extends the knowledge of the biotechnologically relevant SDIMOs by providing functional and evolutionary insights into a group 6 SDIMO in Rhodococcus and demonstrating its key role in the metabolism of short‐chain alkanes and degradation of chlorinated n‐alkanes.
Prevalence of left atrial appendage thrombus and spontaneous echo contrast on transesophageal echocardiography in patients scheduled for pulmonary vein isolation
Authors: Mannewald Christine , Roijer Anders , Platonov Pyotr G. , Holmqvist Fredrik 
Published: April 2024

AbstractBackgroundTo avoid causing a thromboembolic event in patients undergoing catheter ablation for atrial fibrillation (AF), patients are treated with oral anticoagulants (OAC) prior to the procedure. Despite being on anticoagulants, some patients develop a left atrial appendage thrombus (LAAT). To exclude the presence of LAAT, transesophageal ultrasound (TEE) is performed in all patients prior to the procedure. We hypothesized continuous treatment with anticoagulants would result in a low prevalence of LAAT, in patients with low CHA2DS2‐VASc score.MethodMedical records of consecutive patients planned to undergo AF ablation at Lund University Hospital during the years 2018–2020 were reviewed retrospectively. Examination protocols from transesophageal and transthoracic echocardiography were examined for LAAT and spontaneous echo contrast (SEC). Patients with LAAT and SEC were compared to patients without using Mann–Whitney U‐test and Pearson Chi‐squared analysis to test for correlation.ResultsOf 553 patients, three patients (0.54%) had LAAT, and 18 (3.25%) had spontaneous contrast (SEC). Patients with LAAT or SEC had a higher CHA2DS2‐VASc score, more often presented in AF at TEE and less often had a normal sized left atrium.ConclusionThere is a low prevalence of LAAT and SEC in patients with AF scheduled for pulmonary vein isolation. Patients with SEC or LAAT tend to have paroxysmal AF less often and more often presented in AF at admission. No patients with CHA2DS2‐VASc 0, paroxysmal AF, normal sized left atrium and sinus rhythm at TEE were found to have LAAT or SEC.
Functional outcomes following anterior resection for colorectal cancer: a needs assessment and proposal of a nurse‐led remote management algorithm
Authors: Nguyen Thuy‐My , Traeger Luke , Overall Bronwyn , Sammour Tarik , Thomas Michelle 
Published: April 2024

AbstractAimWith the rise of structured, remote follow‐up of colorectal cancers, there is the potential risk of underdiagnosing and undermanaging low anterior resection syndrome (LARS). This cohort study aims to determine the rate of LARS and its patterns of care, with the aim of generating a risk‐stratified management algorithm that can be employed for nurse‐led follow‐up.MethodPatients who underwent elective anterior resection for the management of colorectal cancer between 1 January 2017 and 31 December 2021 were sent quality‐of‐life questionnaires (EORTC‐QLQ‐CR29 and LARS score) and surveyed for LARS symptoms and management utilized.ResultsOut of 70 patients who completed questionnaires, 71.4% had LARS and 42.9% had major LARS. The international Delphi consensus definition identified more patients (n = 50) with LARS than the LARS score (n = 41). Tumours located <8 cm from the anal verge, ULAR, and temporary stoma were predictive of major LARS on univariate analysis. However, only temporary stoma was predictive for LARS (OR 7.89 (1.15–53.95), P = 0.035) and majors LARS (8.14 (1.79–37.01), P = 0.007) on multivariate analysis. Forty‐four percent of patients with LARS did not have input from any health professional for this condition. Consultation with specialist allied health and/or colorectal surgeons ranged from 4% to 22%.ConclusionsOur study highlights that with the current remote follow‐up system focused on cancer outcomes a significant proportion of patients with LARS are overlooked, resulting in the underutilization of relevant health professionals and management options. We propose a nurse‐led management algorithm to address this issue while still minimizing surgical outpatient load.
XRF Analysis of Village and Urban Basalt Architecture in the Hippos Territorium during the Roman Period
Authors: Osband Mechael , Eisenberg Michael , Ferguson Jeffery R. 
Published: April 2024

AbstractThis case study examines the use of X‐ray fluorescence (XRF) as an effective method for defining distinct chemical compositions of local basalt stone from different sources in the Roman period, even when their quarries have not been identified. It also deals with the archaeological question if public and monumental structures from a village and urban site shared the same stone sources and stonemason's workshops. Ninety‐six samples from the Hippos Territorium, mainly from the polis of Hippos and the village of Majduliyya, were analyzed. XRF was found to be an effective method for defining distinct chemical compositions of local basalt materials from different sources. The distinct composition of the basalt stones between the two sites provided valuable insights into socio‐economic relationships, shedding light on the nature of city–village dynamics in the region. Additionally, it aids in discerning whether diverse basalt sources were utilized in both private and public constructions, as well as installations within a single site. Methodological questions and the application of this method in the archaeological research of basalt‐based architecture are also addressed.
A review on the nexus of autophagy genes from the perspective of polycystic ovary syndrome
Authors: Khatun Arifa , Nasrin Taslima , Hassan Md Samim , Hoque Mehboob , Hoda Muddasarul , Ali Safdar 
Published: April 2024

AbstractPolycystic ovary syndrome or PCOS is an endocrine disorder in women of reproductive age. It is a diversified multi factorial disorder and diagnosis is very complicated because of its overlapping symptoms some of which are irregular menstrual cycle, acne in face, excess level of androgen (AE), insulin resistance, obesity, cardiovascular disease, mood disorder and type 2 diabetes (T2DM). PCOS may be caused by hormonal imbalance, genetic and epigenetic vulnerability, hypothalamic and ovarian troubles. PCOS is essentially hyperandrogenimia with oligo‐anovulation. This review explains the abnormal regulation of autophagy related genes and proteins in different cells at various stages which leads to the genesis of PCOS. During nutrient starvation cells face stress condition, which it tries to overcome by activating its macroautophagy mechanism and by degrading the cytoplasmic material. This provides energy to the cell facilitating its survival. Downregulation of autophagy related genes in endometria has been observed in PCOS women. PCOS can be managed by maintaining proper lifestyle and medical treatment. Healthy meals and regular exercise can prevent the excessive weight and also reduce the PCOS complications. Medicines such as metformin, clomiphene, and the oral contraceptive pill can also balance the hormonal level. The imbalance in regulation of autophagy genes has been discussed with correlation to PCOS. The different management strategies for PCOS have also been summarized.
AdipoRon promotes amyloid‐β clearance through enhancing autophagy via nuclear GAPDH‐induced sirtuin 1 activation in Alzheimer's disease
Authors: Sun Fengjiao , Wang Jiangong , Meng Lingbin , Zhou Zhenyu , Xu Yong , Yang Meizi , Li Yixin , Jiang Tianrui , Liu Bin , Yan Haijing 
Published: April 2024

AbstractBackground and PurposeAmyloid‐β (Aβ) peptide is one of the more important pathological markers in Alzheimer's disease (AD). The development of AD impairs autophagy, which results in an imbalanced clearance of Aβ. Our previous research demonstrated that AdipoRon, an agonist of adiponectin receptors, decreased the deposition of Aβ and enhanced cognitive function in AD. However, the exact mechanisms by which AdipoRon affects Aβ clearance remain unclear.Experimental ApproachWe studied how AdipoRon affects autophagy in HT22 cells and APP/PS1 transgenic mice. We also investigated the signalling pathway involved and used pharmacological inhibitors to examine the role of autophagy in this process.Key ResultsAdipoRon promotes Aβ clearance by activating neuronal autophagy in the APP/PS1 transgenic mice. Interestingly, we found that AdipoRon induces the nuclear translocation of GAPDH, where it interacts with the SIRT1/DBC1 complex. This interaction then leads to the release of DBC1 and the activation of SIRT1, which in turn activates autophagy. Importantly, we found that inhibiting either GAPDH or SIRT1 to suppress the activity of SIRT1 counteracts the elevated autophagy and decreased Aβ deposition caused by AdipoRon. This suggests that SIRT1 plays a critical role in the effect of AdipoRon on autophagic induction in AD.Conclusion and ImplicationsAdipoRon promotes the clearance of Aβ by enhancing autophagy through the AdipoR1/AMPK‐dependent nuclear translocation of GAPDH and subsequent activation of SIRT1. This novel molecular pathway sheds light on the modulation of autophagy in AD and may lead to the development of new therapeutic strategies targeting this pathway.