bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Double 1,3‐Dipolar Cycloaddition of N‐Methyl Azomethine Ylide to Meta‐Dinitrobenzene Anellated with Nitrogen Aromatic Heterocycles.
Authors: Bastrakov Maxim A. , Starosotnikov Alexey M. , Pechenkin Sergey Yu. , Kachala Vadim V. , Glukhov Ivan V. , Shevelev Svyatoslav A. 
Published: November 2010

AbstractThe 1,3‐dipolar cycloaddition of a sarcosine‐derived unstabilized azomethine ylide to m‐dinitrobenzenes fused with nitrogen heterocycles is studied.
ChemInform Abstract: Deprotonative Metalation of Substituted Benzenes and Heteroaromatics Using Amino/Alkyl Mixed Lithium—Zinc Combinations.
Authors: Snegaroff Katia , Komagawa Shinsuke , Chevallier Floris , Gros Philippe C. , Golhen Stephane , Roisnel Thierry , Uchiyama Masanobu , Mongin Florence 
Published: November 2010

AbstractThe ability of various mixtures of lithium and zinc compounds to metalate aromatics, including heterocycles, is studied.
ChemInform Abstract: Reversal of Stereoselectivity in the Cu‐Catalyzed Conjugate Addition Reaction of Dialkylzinc to Cyclic Enone in the Presence of a Chiral Azolium Compound.
Authors: Shibata Naoatsu , Okamoto Masaki , Yamamoto Yuko , Sakaguchi Satoshi 
Published: November 2010

AbstractThe addition of dialkylzinc to cyclic enones can give the (R)‐ and/or (S)‐enantiomers using the same chiral ligand AZO but different Cu salts.
ChemInform Abstract: NbCl3‐Catalyzed Intermolecular [2 + 2 + 2] Cycloaddition of Alkynes and α,ω‐Dienes: Highly Chemo‐ and Regioselective Formation of 5‐ω‐Alkenyl‐1,4‐substituted‐1,3‐cyclohexadiene Derivatives.
Authors: Obora Yasushi , Satoh Yasushi , Ishii Yasutaka 
Published: November 2010

AbstractThe products can smoothly be converted into carbonyl derivatives.
ChemInform Abstract: A Concise Synthesis of (S)‐(+)‐Ginnol (VIb) Based on Catalytic Enantioselective Addition of Commercially Unavailable Di(n‐alkyl)zinc to Aldehydes and Ketones.
Authors: Hatano Manabu , Mizuno Tomokazu , Ishihara Kazuaki 
Published: November 2010

AbstractThe process utilizes non‐commmercially available dialkylzincs, which are freshly prepared from ZnCl2 and Grignard reagents.
ChemInform Abstract: A Practical Protocol for the Highly (E)‐Selective Formation of Aryl‐Substituted Silylketene Acetals.
Authors: Harker Wesley R. R. , Carswell Emma L. , Carbery David R. 
Published: November 2010

AbstractSlow addition of the ester (I) to a mixture of LiN(Tms)2 and TmsCl at 95 °C is found to allow formation of aryl‐substituted silylketene acetals with excellent (E)‐selectivity.
ChemInform Abstract: Aromatization of 1,3‐Cyclohexanediones Mediated by Bis‐(trichloromethyl) Carbonate/DMF System.
Authors: Liang X. R. , Shi F. , Chen R. E. , Su W. K. 
Published: November 2010

AbstractA new application of the Vilsmeier reagent for the transformation of different 1,3‐cyclohexanediones into polysubstituted chlorobenzaldehydes is presented.
ChemInform Abstract: Direct Acylation of Aryl Chlorides with Aldehydes by Palladium—Pyrrolidine Cocatalysis.
Authors: Colbon Paul , Ruan Jiwu , Purdie Mark , Xiao Jianliang 
Published: November 2010

AbstractA number of aryl chlorides undergoes direct acylation with various aldehydes under the optimized conditions shown.
ChemInform Abstract: Reaction of N‐Tosylated Imines with α,β‐Acetylenic Ketones via Organozinc Species.
Authors: Liu Yong‐Kang , Wu Quan‐Ping , Guo Qing‐Xiang , Xue Song 
Published: November 2010

AbstractAn efficient method for the stereoselective synthesis of functionalized trisubstituted olefins (V) (22 examples) via one‐pot three‐component reaction of imines (III) with α,β‐acetylenic ketones (IV) and organo‐zinc species (II) is developed.
ChemInform Abstract: 1‐Propanephosphonic Acid Cyclic Anhydride (T3P) as an Efficient Promoter for the Lossen Rearrangement: Application to the Synthesis of Urea and Carbamate Derivatives.
Authors: Vasantha Basavalingappa , Hemantha Hosahalli P. , Sureshbabu Vommina V. 
Published: November 2010

AbstractA convenient procedure is presented for the conversion of aromatic acids and amino acids into hydroxamates using T3P as activator.
ChemInform Abstract: Novel Synthetic Methodologies. Part 202. An Efficient Multicomponent Synthesis of Polysubstituted Pyrrolidines and Tetrahydropyrimidines Starting Directly from Nitro Compounds in Water.
Authors: Das Biswanath , Shinde Digambar Balaji , Kanth Boddu Shashi , Satyalakshmi Gandham 
Published: November 2010

AbstractThe reaction of acetylenedicarboxylates, nitrobenzenes and formaldehyde results in formation of pyrrolidinediones or tetrahydropyrimidines depending on the amounts of nitroarenes used.
ChemInform Abstract: Montmorillonite K10: Catalyst for Friedel—Crafts Alkylation of Indoles and Pyrrole with Nitroalkenes under Solventless Conditions.
Authors: An Li‐Tao , Zhang Li‐Li , Zou Jian‐Ping , Zhang Guang‐Liang 
Published: November 2010

AbstractThe green catalyst montmorillonite K10 can be reused three times without considerable loss of activity.
ChemInform Abstract: Synthesis and in vitro Evaluation of N‐Alkyl‐3‐hydroxy‐3‐ (2‐imino‐3‐methyl‐5‐oxoimidazolidin‐4‐yl)indolin‐2‐one Analogues as Potential Anticancer Agents.
Authors: Penthala Narsimha Reddy , Yerramreddy Thirupathi Reddy , Madadi Nikhil Reddy , Crooks Peter A. 
Published: November 2010

AbstractNewly synthesized title compounds (III) are evaluated for in vitro cytotoxicity against a panel of 57 human tumor cell lines.
ChemInform Abstract: Switching the Reaction Mode of 4‐Methoxycarbonyl‐4‐chloro‐5‐spirocyclopropaneisoxazolidines by N‐Aryl Substitution.
Authors: Cicchi Stefano , Revuelta Julia , Objartel Ina , de Meijere Armin , Brandi Alberto 
Published: November 2010

Abstract1,3‐Dipolar cycloaddition of N‐aryl substituted nitrones with 2‐chlorocyclopropylideneacetate forms unstable isoxazolidines which undergo an unprecedented rearrangement to yield tetrahydropyridones instead of the expected δ‐lactams.
ChemInform Abstract: Synthesis of Imidazo[1,2‐a]pyridines via Three‐Component Reaction of 2‐Aminopyridines, Aldehydes and Alkynes.
Authors: Liu Ping , Fang Li‐song , Lei Xinsheng , Lin Guo‐qiang 
Published: November 2010

AbstractThe novel Cu‐catalyzed approach tolerates a variety of functionalities at the substrates.
ChemInform Abstract: One‐Pot Double Suzuki Couplings of Dichloropyrimidines.
Authors: Anderson Samantha C. , Handy Scott T. 
Published: November 2010

AbstractReaction conditions are developed for a sequential Suzuki coupling of substrate (I) with 2 different arylboronic acids which allow the synthesis of diarylated pyrimidines in a one‐pot manner.
ChemInform Abstract: Synthesis of New Pyrazolo[1.5.4‐de]quinoxalines.
Authors: Boutayeb Mohammed , El Imadi Soufiane , Benchidmi Mohammed , Essassi El Mokhtar , Es‐Safi Nour‐Eddine , El Ammari Lahcen 
Published: November 2010

AbstractThe initiatory heterocyclization yields regioselectively the novel pyrazolo[1,5,4‐de]quinoxaline (III) whose bromination followed by nucleophilic substitution gives the new tetracyclic system (VII).
ChemInform Abstract: Facile One‐Pot Synthesis of Ferrocene‐Based Spiropyrrolidines and Pyrrolizidines Through 1,3‐Dipolar Cycloaddition Reaction.
Authors: Babu A. R. Suresh , Raghunathan R. 
Published: November 2010

AbstractHitherto unknown title compounds, e.g. (IV) and (VI), are prepared by 1,3‐dipolar cycloaddition of azomethine ylides, generated from acenaphthalene quinone (II) with amino acids (III) and (V), with ferrocene dipolarophiles (I).
ChemInform Abstract: Mild and Efficient Method to Obtain Glycosyl Sulfones of Mercaptotriazole.
Authors: Lascu Anca , Sisu Ioana , Bercean Vasile , Lupea Alfa Xenia , Caproiu Miron T. , Sisu Eugen 
Published: November 2010

AbstractEfficient oxidation of thioglycosides of mercaptotriazoles is achieved using KMnO4/CuSO4·5H2O as mild and efficient reagent.
ChemInform Abstract: New Synthetic Routes to Acronycine, Noracronycine, and Their Analogues.
Authors: Hari Galla Sri , Lee Yong Rok , Wang Xue , Lyoo Won Seok , Kim Sung Hong 
Published: November 2010

AbstractNew synthetic routes to acronycine (Ia), noracronycine (Ib), and some of their analogues by using standard methodologies are presented.
ChemInform Abstract: Paleic Acid, a Fatty Acid from Paenibacillus sp.; Taxonomy, Fermentation, Isolation, Structure Determination, and anti‐Mannheimia and ‐Pasteurella Activity.
Authors: Watanabe Takumi , et al. et al. 
Published: November 2010

AbstractPaleic acid (I) is the first reported fatty acid showing antibacterial activities against a number of M.haemolytica and P.multocida strains.
ChemInform Abstract: Metal‐Catalyzed Intramolecular Heteroatom (X) → Carbon (C) Functional Group Migration Reactions Involving Additions of X—Y Bonds Across Alkynes
Authors: Patil Nitin T. , Kavthe Rahul D. , Yamamoto Yoshinori 
Published: November 2010

AbstractReview: about 50 refs.
ChemInform Abstract: (3R,7aS)‐3‐(Trichloromethyl)tetrahydropyrrolo[1,2‐c]oxazole‐1(3H)‐one: An Air and Moisture Stable Reagent for the Synthesis of Optically Active α‐Branched Prolines
Authors: Artman, Gerald D. III , Rafferty Ryan J. , Williams Robert M. 
Published: November 2010

AbstractReview: 9 refs.
The relative exergy array—a new measure for interactions in process design and control
Authors: Montelongo‐Luna Juan M. , Svrcek William Y. , Young Brent R. 
Published: November 2010

AbstractIn this paper, we present the relative exergy array (REA), a tool to measure the relative exergetic efficiency and the controllability of a process when a proposed process and control structure is postulated. The REA is a means to compare thermodynamic efficiency for control structures of multi input–multi output processes. Although only steady‐state information is employed, it is a tool for quick comparison between several candidate process control structures. Guidelines for interpreting the results obtained from the REA are presented and explained. A case study of dual composition control of a distillation column is presented and the results discussed.Une bonne compréhension de tous les domaines du génie chimique ainsi que de nombreux aspects sont nécessaires afin de concevoir efficacement un processus chimique. Par exemple, les organismes gouvernementaux exigent que tous les secteurs d'activité respectent certaines règles en matière d'impact environnemental. L'ingénieur chimiste chargé de concevoir un processus doit prendre ces règles en compte tout en essayant de créer le meilleur processus possible afin d'optimiser les bénéfices. L'exergie peut servir à mesurer la qualité d'un système, notamment en matière d'efficacité du processus. Un processus présente une efficacité thermodynamique élevée et est par conséquent rentable et écoefficace si les valeurs exergétiques des produits issus d'un processus sont proches des valeurs des matières premières. Dans ce document, nous présentons un nouvel outil, le tableau d'exergie relative (TER) permettant de mesurer l'efficacité exergétique relative ainsi que la contrôlabilité d'un processus lorsqu'un processus et une structure de contrôle sont proposés. Le tableau d'exergie relative permet de comparer l'efficacité thermodynamique des structures de contrôle de processus à entrées multiples et sorties multiples. Bien que l'on utilise uniquement l'information de fonctionnement normal, il s'agit d'un outil utile pour comparer rapidement plusieurs structures de contrôle de processus proposées. Ce document présente et explique des directives générales d'interprétation des résultats obtenus grâce au TER. Une étude de cas d'une double structure de contrôle d'une colonne de distillation est également présentée et les résultats sont commentés. © 2010 Canadian Society for Chemical Engineering
Polyphosphates and Pyrophosphates of Hexopyranoses as Allosteric Effectors of Human Hemoglobin: Synthesis, Molecular Recognition, and Effect on Oxygen Release
Authors: Fylaktakidou Konstantina C. , Duarte Carolina D. , Koumbis Alexandros E. , Nicolau Claude , Lehn Jean‐Marie 
Published: November 2010

AbstractPolyphosphorylated and perphosphorylated hexopyranose monosaccharides and disaccharides were synthesized from parent or partially protected carbohydrates as potential allosteric effectors of hemoglobin. A study toward the construction of seven‐ and eight‐membered cyclic pyrophosphates was also performed on the sugars which had the proper orientation, protection, and number of phosphates. All final compounds were tested for their efficiency on oxygen release from human hemoglobin. Several compounds presented higher potency than myo‐inositol hexakisphosphate, which is the most efficient of the known allosteric effectors of hemoglobin. Structure–activity relationships were analyzed. The affinity and efficiency depend on the number of phosphates attached to the carbohydrate skeleton and are related primarily to the number of negative charges present. Other effects operate, but play a lesser role.
Prediction of Rate Constants for Gas‐Phase Reactions of Nitrate Radical with Organic Compounds: A New Structure–Activity Relationship
Authors: Kerdouci Jamila , Picquet‐Varrault Bénédicte , Doussin Jean‐François 
Published: November 2010

AbstractA new structure–activity relationship (SAR), based on parametrization of the molecular structure according to the group‐additivity method, is presented. On the basis of existing experimental data for the degradability of approximately 150 organic compounds by the NO3 radical, this new SAR is developed to estimate the rate constants for reactions with NO3 radical. At night, nitrate radicals are the most important oxidant of volatile organic compounds. The rate constants for their reactions are therefore essential to the understanding of VOC degradation and atmospheric modelling. The database used for the SAR development includes most classes of compounds such as alkanes, alkenes (acyclic and cyclic), dienes, terpenes and saturated and unsaturated oxygenated compounds (including alcohols, ketones, ethers and esters). The proposed SAR shows good efficiency, as 91 % of the rate constants are reproduced within a factor of two. The overall agreement between measured and predicted rate constants is very good for most of the unsaturated and saturated compounds, although for saturated alcohols it is less reliable.
Physiological Responses of Mammals to Overnutrition
Authors: Routh Vanessa H. , Stern Judith S. , Horwitz Barbara A. 
Published: November 2010

AbstractThe sections in this article are:Consequences of OvernutritionThrifty Gene: Altered Lipid MetabolismAnimal ModelsPhysiological ConsequencesFactors Influencing the Response to OvernutritionGenderAgeGeneticsExerciseStressDiet CompositionSeason/Food AvailabilityPhysiological Mechanisms Underlying Responses to OvernutritionCellularEndocrine MechanismsNeural Mechanisms Mediating the Response to OvernutritionSummary
Adaptation to the Microbial Environment
Authors: Toth Linda A. , Blatteis Clark M. 
Published: November 2010

AbstractThe sections in this article are:Relationships Between Microbes and VertebratesCommensal and Mutual Interactions: The Normal FloraParasitic InteractionsAntimicrobial Host DefenseInnate or Nonspecific ImmunityAcquired or Specific ImmunityOther Factors in Host DefenseSummary
A Structurally Diverse RuII,PtII Tetrametallic Motif for Photoinitiated Electron Collection and Photocatalytic Hydrogen Production
Authors: Knoll Jessica D. , Arachchige Shamindri M. , Brewer Karen J. 
Published: November 2010

AbstractCoupling a reactive metal to light absorbers affords molecular devices for photoinitiated electron collection and photocatalytic conversion of substrates to fuels. A new RuII,PtII tetrametallic supramolecule, [{(phen)2Ru(dpp)}2Ru(dpq)PtCl2](PF6)6, and the trimetallic precursors, [{(phen)2Ru(dpp)}2RuCl2](PF6)4 and [{(phen)2Ru(dpp)}2Ru(dpq)](PF6)6, have been synthesized, and their redox, spectroscopic, spectroelectrochemical, photophysical and photocatalytic properties studied. They efficiently absorb UV and visible light. The electrochemistry of [{(phen)2Ru(dpp)}2Ru(dpq)PtCl2](PF6)6 suggests a lowest‐lying terminal Ru→dpq charge‐separated state that quenches the emission of the parent complex with non‐unity population of the emissive 3MLCT excited state. Photolysis of [{(phen)2Ru(dpp)}2Ru(dpq)PtCl2]6+ at 470 nm with DMA gives multielectron reduction, storing electrons in a new manner on the central (dpp)2RuII(dpq) moiety. Addition of H2O to the photolysis system produces 21 μmol of H2 in 5 h, with 115 turnovers of the tetrametallic photocatalyst.
Tinman is a direct activator of midline in the drosophila dorsal vessel
Authors: Ryu Jae‐Ryeon , Najand Nima , Brook William J. 
Published: November 2010

AbstractHeart development requires a conserved core of transcription factors comprised of Nkx2.5, GATA and T‐box family transcription factors. In Drosophila melanogaster, the Nkx2.5 gene tinman acts upstream of many cardiac genes including the Tbx20 homolog midline, a critical regulator of heart development in both flies and vertebrates. By testing genomic fragments containing clusters of consensus Tinman‐binding sites, we identified a 4.3 kb fragment 5′ of midline that directs reporter expression in all midline‐expressing heart cells and a 1.7 kb subfragment that drives reporter expression in mid‐expressing heart cells that maintain tin expression. Both fragments direct reporter gene expression in response to tinman in transgenic embryos and in transient transfection assays in Drosophila S2 cells. Mutation of two Tinman binding sites (Tin1 and Tin2) reduces or abolishes cardiac expression in derivatives of the 1.7 kb fragment. We conclude that Tin is a direct regulator of midline in fly heart development. Developmental Dynamics, 2011. © 2010 Wiley‐Liss, Inc.
Islet1 selectively promotes peripheral axon outgrowth in Rohon‐Beard primary sensory neurons
Authors: Tanaka Hideomi , Nojima Yasuhiro , Shoji Wataru , Sato Miki , Nakayama Ryoko , Ohshima Toshio , Okamoto Hitoshi 
Published: November 2010

AbstractWe isolated a novel zebrafish mutant, lullaby (llb), and showed that the llb locus encodes the zebrafish orthologue of isl1. Rohon‐Beard (RB) primary sensory neurons are multipolar neurons that extend their central axons longitudinally within the spinal cord and also extend their peripheral axons under the skin. In llb embryos, the outgrowth of the peripheral axons of RB neurons was selectively impaired, which correlated with down‐regulation of the expression of dihydropyrimidinase‐like 3 (dpysl3, also known as collapsin response mediator protein 4, crmp4). Antisense morpholino oligonucleotide (AMO)‐mediated knockdown of dpysl3 inhibited the outgrowth of the peripheral axons of RB neurons, and semaphorin 3d (sema3d) AMO enhanced this effect. These data indicate that Dpysl3 is cooperating with Sema3d in the peripheral axon outgrowth, and Isl1 is required for the selective outgrowth of the peripheral axons of RB neurons by maintaining the expression of dpysl3. Developmental Dynamics 240:9–22, 2011. © 2010 Wiley‐Liss, Inc.
Accountable governance, accountable sustainability? a case study of accountability in the governance for sustainability
Authors: Joss Simon 
Published: November 2010

AbstractThis article provides a conceptual framework for, and comparative analysis of, public accountability in relation to three recent British exemplars of governance for sustainability: the GM Nation public consultation on the use of genetically modified crops in agriculture; the South East London Combined Heat and Power waste incinerator to achieve a shift away from landfill waste disposal; and the London Underground public–private partnership to provide more long‐term financial and technological investment in a key area of public transport. Each of these initiatives is characterized by distinct public accountability features arising partly from the context‐specific tensions between environmental sustainability and economic and technological development, and partly from the particular governance processes at work. Together, these features point to several significant accountability shortcomings facing the governance of sustainable development, including: the compartmentalization of decision‐making processes; the blurring of boundaries of responsibility; the prevalence of professional‐technocratic discourses; and the marginalization of publicity. The article concludes by outlining measures to improve accountability in the governance for sustainability. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
TNF superfamily member 13, APRIL, inhibits allergic lung inflammation
Authors: Xiao Yanping , Motomura Seiichi , Deyev Vadim , Podack Eckhard R. 
Published: November 2010

AbstractThe T‐cell functions of a proliferation‐inducing ligand (APRIL, also known as TNFSF13) remain largely undefined. We previously showed that APRIL suppressed Th2 cytokine production in cultured CD4+ T cells and Th2 antibody responses. Here we show that APRIL suppresses allergic lung inflammation, which is associated with diminished expression of the transcription factor c‐maf. Mice deficient in the April gene (April−/− mice) had significantly aggravated lung inflammation compared with WT mice in the ovalbumin‐induced allergic lung inflammation model. Likewise, blockade of APRIL in WT mice by the APRIL‐receptor fusion protein, transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI)‐Ig, enhanced lung inflammation. Transfer of APRIL‐sufficient, ovalbumin‐specific, TCR‐transgenic CD4+ T (OT‐II) cells to April−/− mice restored the suppressive effect of APRIL on lung inflammation. Mechanistically, the expression of the Th2 cytokine transcription factor c‐maf, but not GATA‐3, was markedly enhanced in April−/− CD4+ T cells at the RNA and protein level and under non‐polarizing (Th neutral, ThN) and Th2‐polarizing conditions. Since c‐maf transactivates the IL‐4 gene, the increased c‐maf expression in April−/− mice readily explains increased Th2 cytokine production. Independent of its effect on IL‐4, APRIL suppressed IL‐13 expression. APRIL thus may regulate lung inflammation in a dual way, by acting on c‐maf expression and by directly controlling IL‐13 production.
An Imidazolate‐ and Azide‐Bridged Copper(II) Coordination Polymer Consisting of Alternating Di‐ and Mononuclear Units
Authors: Sakai Ken‐ichi , Akutagawa Tomoyuki , Nakamura Takayoshi 
Published: November 2010

AbstractUsing the CuII‐imidazole(Him) complex [Cu(Him)4Cl]Cl as the starting material, the imidazolate (im)‐ and azide‐bridged CuII coordination polymer [Cu3(Him)4(im)2(N3)4]n was successfully obtained. Single‐crystal X‐ray analysis revealed that it possesses an im‐bridged linear‐chain structure consisting of alternating dinuclear units with a symmetric end‐on azide‐bridged [Cu(μ1,1‐N3)2Cu]2+ core and mononuclear units. All of the Cu ions adopt a square pyramidal geometry with an azide at the Jahn–Teller elongated apical position. Some of the azides act as end‐to‐end interchain bridging ligands from the mononuclear unit to the nearest neighbouring dinuclear unit of the adjacent chain forming a two‐dimensional network. Temperature‐variable magnetic susceptibility measurements showed that it exhibits one‐dimensional ferrimagnetic‐like behaviour, which can be ascribed to two types of exchange couplings with opposite signs, namely a weak ferromagnetic coupling through the end‐on azide bridges within the dinuclear units and a stronger antiferromagnetic coupling through the im bridges between the di‐ and the mononuclear units.