bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estrone Sulfatase Activity in Normal and Neoplastic Endometrial Tissues of Human Uterus
Authors: Urabe Mamoru , Yamamoto Takara , Naitoh Kazuo , Honjo Hideo , Okada Hiroji 
Published: August 2010

AbstractEstrone sulfatase activity was measured in normal and neoplastic endometrial tissues of human uterus. The tissue homogenates were incubated in air with [3H] estrone sulfate (E1‐S, 20 μM) at 37·C for 30 min. After the enzyme reaction was terminated with ethyl ether, the ethyl ether extract was purified by thin‐layer chromatography. The apparent Km of sulfatase was 3.0 μM, and the maximum velocity was 14.7 nmol/h/mg protein. Estrone sulfatase activity in endometrial tissues was detected throughout the menstrual cycle with no significant change. Moreover, estrone sulfatase activity in endometrial cells was not stimulated by the addition of progestogen. The enzyme activity in cancer tissue was significantly higher than in normal tissue. Thus we concluded that this enzyme may play a role in regulating the estrogen action by sifting the intracellular equilibrium between free estrogens and estrogen sulfates. We also concluded that in the endometrial cancer tissue, sulfatase appears to act on local production of estrone.
Meconium Peritonitis Due to Meconium Ileus Presenting as Fetal Ascites: A Case Report
Authors: Rachagan S. P. , Lim C. T. , Chang K. W. , Kwan B. B. 
Published: August 2010

AbstractA case of meconium peritonitis due to meconium ileus is described. The condition was detected antenatally as fetal ascites on ultrasonography. Plain X‐ray of abdomen post‐natally showed specks of calcification mainly at the flanks, while on ultrasonography specks of high echogenic areas were seen throughout the abdomen which has been described as “snow‐storm sign”. The aetiology of meconium ileus is briefly discussed.
Vaginal Delivery in First Pregnancy Following a Primary Caesarean Section
Authors: Ojo Vincent A. , Okwerekwu Francis O. 
Published: August 2010

AbstractA retrospective study was performed on 131 women who had trial of scar in their first pregnancies following a primary caesarean section. The vaginal delivery rate was 81.7% and this rate was not significantly influenced by the indication for the previous caesarean section. It is advocated that patients for trial of scar should be selected on individual merits rather than on the nature of the indication for previous caesarean section.
Recurrent Pancreatitis in the Third Trimester in 2 Consecutive Pregnancies—Its Relationship to Liver Histology: A Case Report
Authors: Minakami Hisanori , Nakayama Hiroshi , Yano Hitoshi , Tamada Taro , Yasuda Yoshikazu , Hirota Norio 
Published: August 2010

AbstractA 20‐year‐old woman who had recurrent pancreatitis in the third trimester in 2 consecutive pregnancies was reported. Her liver histology was indistinguishable from acute fatty liver of pregnancy, although she showed no clinical signs. The relationship between idiopathic acute pancreatitis during pregnancy and acute fatty liver of pregnancy was discussed.
Leukoencephalopathy Following Treatment with Carmofur: A Case Report and Review of the Japanese Literature
Authors: Yamada Takashi , Okamura Shinsuke , Okazaki Tadashi , Ushiroyama Takahisa , Yanagawa Yasuhiko , Ueki Minoru , Sugimoto Osamu , Yamazaki Hidetomo , Sugino Masakazu , Masui Yoshikazu 
Published: August 2010

AbstractA 53‐year‐old woman was treated with 5 courses of CAP treatment following operation for FIGO Stage Ia cancer of the ovary in September 1986. And in April 1987, she started an oral adjuvant chemotherapy with 400 mg/day of carmofur. In early June, she developed vertigo and dysarthia and was hospitalized. A CT scan showed low‐density areas adjacent to both lateral ventricles, and an EEG revealed abnormally slow waves. She improved gradually after carmofur was discontinued and left the hospital in October 1987.There have been 24 reported cases of leukoencephalopathy because of carmofur in Japan, but the pathophysiological mechanism involved is not known. Since it is more common in women than in men, its incidence will probably increase in gynecological patients. Therefore, we must be on the lookout for central nervous system signs and symptoms in patients receiving adjuvant chemotherapy with carmofur.
Plasma Concentrations of Human Atrial Natriuretic Peptide at Vaginal Delivery and Elective Cesarean Section
Authors: Okamoto Eisaku , Otsuki Yoshiro , Iwata Itsuko , Nishino Eriko , Mitsuda Nobuaki , Takagi Tetsu , Sugita Nagatoshi , Tanizawa Osamu 
Published: August 2010

AbstractThe change in plasma concentration of atrial natriuretic peptide (hANP) at delivery was examined by measuring the concentrations of hANP in plasma samples from 21 subjects after 36 weeks of normal pregnancy, 22 subjects after normal spontaneous delivery and 20 subjects after elective cesarean section. The maternal plasma concentration of hANP after normal delivery (38.0 · 8.2 fmol/ml, mean · S.E.M.) was significantly higher than that after 36 weeks of normal pregnancy (16.8 · 2.3 fmol/ml), but its concentration after cesarean section was not different from that after 36 weeks of pregnancy. After normal delivery, the plasma concentration of hANP in the umbilical artery (66.9 · 11.8 fmol/ml) was also significantly higher than that in the umbilical vein (35.1 · 7.3 fmol/ml). In contrast, after elective cesarean section, the hANP levels in the umbilical artery and vein were not significantly different. These results suggest that hANP secretion into the maternal and fetal circulation may be stimulated by the dynamic movement of the mother in labour and the stress of the fetus at delivery, respectively.
Biparietal Diameter of Nepalese Foetus in Different Periods of Gestation by Ultrasonography
Authors: Dali Sanu M. , Shrestha Basanta L. 
Published: August 2010

AbstractThis study presents an analysis of 316 primigravidas with their known date of last menstruation. These cases have been attending antenatal clinic from 14 to 40 weeks of gestation. The mean BPD (Biparietal Diameter) values and percentile values were calculated. It was observed that there is a steep rise of growth up to 31 weeks and thereafter a gradual rise up to 40 weeks. The maximum BPD from 31 to 40 weeks was 90.9 mm whereas western workers like Hansmann and Campbell reported 99 mm and 98.1 mm, respectively. Several factors like nutrition and hereditary may have influenced the foetus after 30 weeks leading to low birth weight in our newborns.
Patent Omphalomesenteric Duct: A Case Report and Review of Japanese Literature
Authors: Yamada Takashi , Seiki Yasuo , Ueda Masatsugu , Yoshikawa Takuji , Sempuku Sadahiro , Kurokawa Akio , Nakata Katsuji 
Published: August 2010

AbstractPatent omphalomesenteric duct (umbilical enteric fistula) was diagnosed in a 7‐day‐old infant. The duct closed spontaneously, but at the age of 4 months the infant was readmitted for a resection of the duct.A review of the literature disclosed that 65 cases of patent omphalomesenteric duct have been reported in Japan. The male/female ratio was 2.8: 1. Ten out of 36 infants (27.8%) were premature. Surgery was performed in as many patients as possible—55 out of 59 cases (93.2%). The ducts averaged 3.8 cm in length and 1.1 cm in diameter. Errant gastric mucosa was found in 3 out of 30 cases (10.0%). Prolapse of the ileum was present in 28 out of 53 patients (52.8%)—a relatively high incidence. Ten out of 55 patients died (18.2%); 8 of these had a prolapse of the ileum.In view of the high mortality rate of patients with a prolapse of the ileum and the strong possibility of intestinal obstruction, patent omphalomesenteric ducts should be resected surgically.
Tubal Cyst Following Tubal Sterilization: A Delayed Complication
Authors: Lin Ho‐Hsiung , Hwang Wen‐Jang , Ho Hong‐Nerng , Hshieh Fon‐Jou , Lee Tzu‐Yao , How Shu‐Wen 
Published: August 2010

AbstractClinical pictures and histopathological findings in 15 patients of tubal cyst following tubal sterilization were analyzed. The interval between tubal sterilization and occurrence of tubal cyst was 10 years (ranged from 4 to 21 years). Clinically 8 cases (53%) suffered from lower abdominal pain, 5 cases (33%) from hypermenorrhea coexistent with uterine myoma and 2 cases (13%) from irregular menstruation. Five out of 9 patients with ultrasound examination were suspected to have tubal cyst before operation. The size of tubal cyst ranged from 1.5 to 9.0 cm in diameter with mean 3.4 cm. Eleven were unilateral and 4 were bilateral. Histologically they showed flattened mucosal epithelial cells with absence of epithelial plica, compression atrophy of muscular layer, suture stitch or granuloma and intact fimbria with clear serous fluid. Thus, the differential diagnosis of adnexal cyst in patients with a past history of tubal sterilization should include tubal cyst.
Hepatocellular Lipofuscin in Pre‐Eclampsia
Authors: Minakami Hisanori , Kimura Kozo , Tamada Taro , Yasuda Yoshikazu , Hirota Norio 
Published: August 2010

AbstractThirty liver specimens from 30 pre‐eclamptic women with and without liver dysfunction were examined for the amount of lipofuscin pigment deposited. The amount of hepatic lipofuscin correlated positively with plasma urate concentrations. This finding may indicate an involvement of oxygen‐free radicals and xanthine oxidase in the pathophysiology of pre‐eclampsia.
Metabolism of Amniotic Fluid Dopamine by Fetal Membranes
Authors: Kawada Akinori , Kudo Takafumi , Kishimoto Yasuo 
Published: August 2010

AbstractThe concentrations of L‐dopa, three catecholamines and 3,4‐dihydroxyphenylacetic acid (DOPAC) were measured both in the amniotic fluid and the fetal urine obtained at term elective cesarean section, using high performance liquid chromotography with electrochemical detection. Dopamine was the major compound in the fetal urine, while DOPAC predominated in the amniotic fluid. Monoamine oxidase (MAO) activity was detected in the fetal membranes by the method of Wurthman and Axelrod. MAO activities in the amnion, chorion and decidua were 0.023·0.003, 0.180·0.05 and 2.69·0.66 nmol/mg protein/min (meanSE), respectively. Incubation experiments, using fetal membranes with human amniotic fluid, demonstrated that dopamine in amniotic fluid was metabolized to DOPAC by fetal membranes. Additional incubation experiments with pargyline, a MAO inhibitor, showed that it strongly inhibited the conversion of dopamine into DOPAC. These results suggest that the dopamine in amniotic fluid was metabolized to DOPAC by MAO in the fetal membranes. This mechanism may regulate the dopamine concentration in amniotic fluid.
A Rise in the Biologically Active LH: Immunologically Active LH (B/I) Ratio during the Normal Luteal Phase
Authors: Tennekoon Kamani H. , Lenton Elizabeth A. 
Published: August 2010

AbstractBiologically active (bio) LH concentrations and immunologically active (immuno) LH concentrations were measured in integrated hourly blood samples collected over 24 h study periods (n=27) and in 5 min blood samples collected over 2 h study periods (n=21) during different stages of the menstrual cycle in a group of regularly cyclic women. Episodic fluctuations were seen in both the bio LH and immuno LH concentrations in hourly as well as in 5 min data series. However, there was no consistent correlation between episodes of bio LH and immuno LH. Mean B/I ratio over the 24 h study periods as well as over the 2 h study periods were significantly higher during the luteal phase than during either the follicular phase (p<0.002) or the mid cycle (p<0.02).
Coital Urinary Incontinence in an Australian Population
Authors: Korda Andrew , Cooper Michael , Hunter Peter 
Published: August 2010

AbstractA total of 1,012 patients referred to 4 urodynamic centres were questioned, and subsequently investigated. Coital incontinence was present in 192 of the 839 (23%), who were sexually active. Ninety‐five patients (49%) had the urodynamic diagnosis of genuine stress incontinence, alone or in association with cystocoele or interstitial cystitis. Fifty‐one (26.6%) had urodynamically proven detrusor instability with or without interstitial cystitis. Forty‐five (23.4%) had dual pathology as the final urodynamic diagnosis.
The Simultaneous Use of Autologous Blood Transfusion and Hypotensive Anesthesia to the Radical Hysterectomy for Uterine Carcinomas
Authors: Yamasaki Masato , Sawada Masumi , Urabe Takeshi , Okamoto Etsuji , Shimizu Hiromu , Takemura Masahiko , Ohama Koso 
Published: August 2010

AbstractA homologous blood transfusion is often required to replace intraoperative blood loss in a radical hysterectomy. Recently, we have tried the simultaneous use of autotransfusion (predonation and transfusion of autologous blood) and hypotensive anesthesia to eliminate the homologous blood transfusion. Radical hysterectomy was done in 27 cases with uterine cancer from June 1986 to March 1987 at the Kure National Hospital.A homologous blood transfusion was required in 1 of 5 cases with only autotransfusion, none of 5 cases with a simultaneous use of autotransfusion and hypotensive anesthesia, and 6 of 17 cases with neither autotransfusion nor hypotensive anesthesia.The simultaneous use of autotransfusion and hypotensive anesthesia seemed to be effective in reducing the need for homologous blood transfusions.
The Prognostic Value of a Prior Spermatozoa Study for Human in vitro Fertilization
Authors: Tam P.P.L. , Loong E.P.L. , Chan C. , Chiu T. , Hui N. 
Published: August 2010

AbstractPatients admitted for treatment of in vitro fertilization (IVF) were subjected to a semen investigation about 1–2 weeks prior to actual IVF and again during IVF. In addition to routine semen analyses, the recovery efficiency of motile spermatozoa by swim‐up technique and Percoll gradient separation, the level of semen lactate dehydrogenase and the viability of the spermatozoa in the insemination medium were also studied. There is a significant correlation between the result of the pre‐IVF analyses and that observed during IVF suggesting that a prior investigation of semen profile and sperm function is useful to screen potential IVF candidates. Among the various parameters, sperm motility in the semen and the swim‐up preparation, percent normal spermatozoa and in vitro viability were significantly related to the outcome of IVF.
Perinatal Risk Factors in Birth Asphyxia: Relationship of Obstetric and Neonatal Complications to Neonatal Mortality in 16,365 Consecutive Live Births
Authors: Mir Nisar A. , Faquih A. M. , Legnain M. 
Published: August 2010

AbstractOver a period of one year, 16,365 consecutively live born neonates were prospectively studied for evidence of birth asphyxia using the requirement of greater than one minute of positive pressure ventilation for identifying infants suffering from birth asphyxia. Asphyxia occurred in 2.8% of all neonates. Multivariate analysis of high risk factors associated with increased risk of asphyxia showed that low birth weight was the most significant predictor of asphyxia: asphyxia occurred in 68% of infants of <1,000 g birth weight and decreased to 1.2% in infants of 3–4 kg birth weight. Perinatal risk factors associated with a higher incidence of asphyxia include: postmaturity, birth weight (2.5 kg) and with the presence of maternal and/or obstetric complications.The impact of asphyxia on neonatal mortality was most pronounced in more mature infants and the mortality was increased 3 fold in infants of <34 week gestation and greater than 27 fold for infants >38 week gestation. Of the asphyxiated neonates, intrauterine growth retardation, fetal macrosomia, hypothermia, hyaline membrane disease, seizures, hypoglycemia and hyponatremia were significantly associated with an increased risk of death.
Non‐Steroidal Low Molecular Substance from Porcine Follicular Fluid Inhibits Aromatase Activity
Authors: Miyamura Kenji , Ogawa Takako , Narahara Hisashi , Mori Hiroyuki , Kigawa Tomonori 
Published: August 2010

AbstractTo clarify the underlying mechanism of the inhibitory control of the non‐steroidal substance from porcine follicular fluid on estradiol secretion by granulosa cells, the suppression of aromatase activity was studied in vitro. Follicular fluid from porcine small follicles was filtered through an Amicon PM‐10 membrane and a filtrate with a molecular weight of less than 10,000 was obtained. The filtrate was eluted on a Sephadex G‐25 column (1.5 × 70 cm) using 0.01N CH3COOH, pH 4.0 as the elution buffer. The fraction containing the first peak of peptide (Fraction A) was used for subsequent experiments. Human placental microsomal fraction was used for the aromatase source. Aromatase activity was examined by counting the radio‐activity of 3H2O converted from (1β, 2β 8H)‐testosterone. The conversion of 3H2O from (1β, 2β 3H)‐testosterone by rat's granulosa cells cultured in serum‐free medium was also examined. Fraction A significantly suppressed aromatase activity of placental microsomal fraction by 57% at 120 min, and by 38% at 180 min, in dose and time‐dependent manners. The aromatase activity of cultured rat granulosa cells was also inhibited by Fraction A in a dose‐dependent manner. These results demonstrate the presence of a low molecular non‐steroidal substance in the follicular fluid which is capable of inhibiting aromatase activity. This substance could provide important insights into the regulatory mechanism of differentiated functions of granulosa cells.
The Effects of Insulin Antibodies during Diabetic Pregnancy on Newborn Infants
Authors: Murata Kazuhira , Toyoda Nagayasu , Sugiyama Youichi 
Published: August 2010

AbstractLevels of insulin antibody, free insulin, and total insulin in the blood of diabetic mothers and their newborn infants were measured, and the relations of these findings to perinatal complications were studied. The subjects were 35 patients: 8 treated with bovine/porcine insulin, 15 with porcine, and 12 with human insulin. Insulin antibody levels (insulin binding capacity; IBC) in patients injected with bovine/porcine insulin were higher. There was no difference in the insulin antibody levels between the groups treated with porcine and human insulin preparations. Infant insulin antibody levels were close to the mother's levels. Free insulin levels did not correlate with total insulin nor antibody levels, but correlated with plasma glucose levels in the infants. The birth weight did not correlate with insulin antibody levels. The frequency of neonatal hypoglycemia and cord hematocrit levels were increased when the mother's insulin antibody levels were over 20%.We conclude the following: 1) Insulin antibodies are transferred through the placenta; 2) The risk of neonatal hypoglycemia is high if the mother's insulin antibody levels are high; 3) Bovine insulin preparations should not be used.
A Simple Regression Model for Estimating Gestational Age in Later Pregnancy by Ultrasonography
Authors: Ghosh U. K. , Sharma D. , Iliyas H. , Baveja R. 
Published: August 2010

AbstractThree hundred and six antenatal women with confirmed LMP underwent a single real time ultrasonographic examination between 32–40 weeks of gestation. Four parameters viz. BPD, HL, FL and AP having a positive correlation with gestational age were studied. A multiple regression model for predicting gestational age by a single ultrasonographic examination was developed by forward selection method after eliminating multicollinearity; as a high degree of intercorrelation was found between FL and HL, HL was eliminated from the data. The BPD does not have a significant role in predicting gestational age in later pregnancy. The proposed regression equation with FL and AP predicts gestational age 75% of time within ±10 days of 95% confidence limit.
Cellular Immunity in Pregnant and Non‐Pregnant Women with Malarial Infection
Authors: Sholapurkar Shashikant L. , Mahajan Ramesh C. , Gupta Amar N. , Wangoo Arun 
Published: August 2010

AbstractA study of lymphocyte subpopulation and leucocyte migration inhibition index (LMI) in 78 pregnant and 22 nonpregnant women with malarial infection (P. vivax 60% and P. falciparum 40%) was done in a hospital in Northern India. Eighty pregnant and 20 nonpregnant women without any infection were also included in the study as controls. T‐cell percentage in controls decreased to its lowest in first trimester and gradually rose to nonpregnant levels by the end of puerperium. With malarial infection, there was further drop in T‐cell percentage, more so in third trimester. LMI in controls corresponded with T‐cell percentage and was depressed in pregnant patients. Enhancement in LMI with malarial infection was depressed in pregnant patients maximally in the third trimester. Parity did not have any influence on these cellular immune parameters. Thus, cellular immunity status in malarial patients was found to be depressed during pregnancy especially in the third trimester.
Vaginal Delivery following One Previous Cesarean Birth: Nation Wide Survey
Authors: Mor‐Yosef Shlomo , Zeevi Dan , Samueloff Arnon , Donhin Milka , Frankfurter Hadassah , Schenker Joseph G. 
Published: August 2010

AbstractThe present state of vaginal delivery following a previous cesarean section (CS) was evaluated through a nation wide survey, including 22,815 deliveries. The overall cesarean rate was 9.6%. Of all the parturients with one previous cesarean section 55.1% delivered vaginally. A previous CS and labor arrest were the major indications for a repeated CS in 28.7% and 26.4%, respectively. Rupture of the uterus following vaginal delivery was found more often in the group with a previous CS than in those with no uterine scar (1.2% and 0.03%, respectively), (P<0.0001). None of the uterine ruptures was fatal neither to the mother nor to the fetus. Post partum fever appeared more often among vaginal deliveries following a CS than among those with no uterine scar. However, CS is followed by fever 10.8 times more than vaginal delivery. Intrapartum and neonatal death rates following vaginal delivery were similar for those with or without a previous CS (3.42% and 3.38%, respectively). An average of 3 hospitalization days were saved for each vaginal birth replacing a repeated CS. It is concluded that vaginal delivery, following CS, does not cause substantial morbidity, nor mortality either to the mother or the neonate, and may be practiced with a reasonable margin of safety in well selected cases.
Current Method for First and Second Trimester Prenatal Diagnosis: Transabdominal Chorionic Villi Sampling
Authors: Buckshee K. , Parveen S. , Verma I. C. 
Published: August 2010

AbstractTransabdominal CVS (chorionic villi sampling) was performed in 40 patients belonging to first or second trimester of pregnancy with 97.5% success, using a double and later single needle technique with no immediate complications. Karyotyping by direct method was successful in 75% of samples thus indicating the feasibility of cytogenetic analysis using villus tissue from first and second trimesters of pregnancy. It is a safe, simple, rapid and practical method of prenatal diagnosis in first and second trimesters of pregnancy with a potentially lower risk for fetal and maternal complications.