bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial intelligence and radiomics in the diagnosis of intraosseous lesions of the gnathic bones: A systematic review
Authors: Giraldo‐Roldán Daniela , Araújo Anna Luíza Damaceno , Moraes Matheus Cardoso , da Silva Viviane Mariano , Ribeiro Erin Crespo Cordeiro , Cerqueira Matheus , Saldivia‐Siracusa Cristina , Sousa‐Neto Sebastião Silvério , Pérez‐de‐Oliveira Maria Eduarda , Lopes Marcio Ajudarte , Kowalski Luiz Paulo , de Carvalho André Carlos Ponce de Leon Ferreira , Santos‐Silva Alan Roger , Vargas Pablo Agustin 
Published: May 2024

AbstractBackgroundThe purpose of this systematic review (SR) is to gather evidence on the use of machine learning (ML) models in the diagnosis of intraosseous lesions in gnathic bones and to analyze the reliability, impact, and usefulness of such models. This SR was performed in accordance with the PRISMA 2022 guidelines and was registered in the PROSPERO database (CRD42022379298).MethodsThe acronym PICOS was used to structure the inquiry‐focused review question “Is Artificial Intelligence reliable for the diagnosis of intraosseous lesions in gnathic bones?” The literature search was conducted in various electronic databases, including PubMed, Embase, Scopus, Cochrane Library, Web of Science, Lilacs, IEEE Xplore, and Gray Literature (Google Scholar and ProQuest). Risk of bias assessment was performed using PROBAST, and the results were synthesized by considering the task and sampling strategy of the dataset.ResultsTwenty‐six studies were included (21 146 radiographic images). Ameloblastomas, odontogenic keratocysts, dentigerous cysts, and periapical cysts were the most frequently investigated lesions. According to TRIPOD, most studies were classified as type 2 (randomly divided). The F1 score was presented in only 13 studies, which provided the metrics for 20 trials, with a mean of 0.71 (±0.25).ConclusionThere is no conclusive evidence to support the usefulness of ML‐based models in the detection, segmentation, and classification of intraosseous lesions in gnathic bones for routine clinical application. The lack of detail about data sampling, the lack of a comprehensive set of metrics for training and validation, and the absence of external testing limit experiments and hinder proper evaluation of model performance.
Heterogeneity of adolescent bullying perpetrators: Subtypes based on victimization and peer status
Authors: Turunen Tiina , Malamut Sarah T. , Yanagida Takuya , Salmivalli Christina 
Published: May 2024

AbstractWe identified different types of adolescent bullying perpetrators and nonbullies based on peer‐reported bullying, victimization, and peer status (popularity, likeability, and rejection) and examined differences between bully subtypes in typical forms of bullying perpetrated. Moreover, we studied how bully subtypes differed from nonbullies with varying levels of victimization and peer status in academic and psychosocial adjustment. The study utilizes data from 10,689 adolescents (48.3% boys, mean age 14.7 years). Latent profile analysis identified three distinct subgroups of bullies: popular‐liked bullies (13.5%), popular‐rejected bully‐victims (5.8%), and bully‐victims (6.9%), and four groups on nonbullies. High‐status bullies (popular‐liked and popular‐rejected) resembled nonbullies in many ways and had even lower social anxiety, whereas bully‐victims were the most maladjusted group. Overall, popularity seems to protect adolescents from social anxiety, and victimization is related to internalizing problems. Results suggest that bullying, victimization, and peer status can be used to identify distinct subtypes of bullies.
Sinking rates, orientation, and behavior of pennate diatoms
Authors: Sourisseau M. , Font‐Muñoz J. , Bellouche S. , Fauvarque O. , Rouxel J. , Tardivel M. , Sauvey A. 
Published: May 2024

AbstractPhytoplankton cells are now recognized as dynamic entities rather than as passive and isolated particles because they can actively modulate impacts of selection factors (nutrients, light, turbidity, and mixing) through a wide range of adaptations. Cell shape and/or chain length modulation is one of these processes but has predominantly been studied as an adaptation or an acclimatation to a specific growth limitation (light, nutrients, predation, etc.). In this study we have demonstrated that cell shape and size may have greater roles than previously known in phytoplankton ecology and species adaptation by permitting cell‐to‐cell signaling and more complex ecological processes that result from it. By exploring microscale biophysical interactions that lead to specific cell reorientation processes, we demonstrated that cell geometry not only modulates cell sinking rates but can also provide fast sensor responses to the cells' environment. Although gyrotaxis has been described in detail for motile phytoplankton cells, our findings illustrate that the reorientation process described here can occur even in non‐motile cells within their natural environment. An additional consistent behavior was also recently described for a diatom species (Pseudo‐nitzschia delicatessima), and with this study, we extend this observation to Pseudo‐nitzschia pungens and Pseudo‐nitzschia fraudulenta. Our observations emphasize the generality of this process, which adds a new level of complexity to our understanding of cellular interactions and their network of sensors.
Maternal effects on recruitment of five gadoid species
Authors: Jónsdóttir Ingibjörg G. , Sólmundsson Jón , Jonasson Jónas P. , Woods Pamela J. 
Published: May 2024

AbstractCommercial fishing is almost always non‐random and generally removes large and old individuals from fish stocks, thereby reducing age diversity among spawners. Reduced age diversity may result in less stable recruitment. Here, we explore the influence of age diversity (H), mean age of the spawning stock (MA) and sea surface temperature (SST) on recruitment‐per‐spawning biomass (RSSB) for five commercial gadoid species (Atlantic cod, haddock, ling, saithe and tusk) by using data from analytical stock assessment spanning 4–7 decades. In the past 10–20 years, spawning stock biomass of these species (except for tusk) has increased due to lower fishing pressure. Concurrently, H and MA increased, especially for cod. However, our results did not indicate long term either positive or negative correlation between the maternal factors (H and MA) and RSSB for four of the studied species. Cod was the only species that showed significant positive correlation between H and RSSB, but the correlation did not hold during the most recent period of high SST. The conflicting outcomes underscore the difficulty in identifying a constant and direct maternal and/or environmental influence on RSSB.
A MYB‐related transcription factor regulates effector gene expression in an oomycete pathogen
Authors: Qian Hui , Lin Long , Zhang Zhichao , Gu Xinyi , Shen Danyu , Yin Zhiyuan , Ye Wenwu , Dou Daolong , Wang Yuanchao 
Published: May 2024

AbstractPhytophthora pathogens possess hundreds of effector genes that exhibit diverse expression patterns during infection, yet how the expression of effector genes is precisely regulated remains largely elusive. Previous studies have identified a few potential conserved transcription factor binding sites (TFBSs) in the promoters of Phytophthora effector genes. Here, we report a MYB‐related protein, PsMyb37, in Phytophthora sojae, the major causal agent of root and stem rot in soybean. Yeast one‐hybrid and electrophoretic mobility shift assays showed that PsMyb37 binds to the TACATGTA motif, the most prevalent TFBS in effector gene promoters. The knockout mutant of PsMyb37 exhibited significantly reduced virulence on soybean and was more sensitive to oxidative stress. Consistently, transcriptome analysis showed that numerous effector genes associated with suppressing plant immunity or scavenging reactive oxygen species were down‐regulated in the PsMyb37 knockout mutant during infection compared to the wild‐type P. sojae. Several promoters of effector genes were confirmed to drive the expression of luciferase in a reporter assay. These results demonstrate that a MYB‐related transcription factor contributes to the expression of effector genes in P. sojae.
Micronutrient‐fortified bouillon as a strategy to improve the micronutrient adequacy of diets in Burkina Faso
Authors: Adams Katherine P. , Vosti Stephen A. , Somé Jérome W. , Tarini Ann , Becher Emily , Koudougou Karim , Engle‐Stone Reina 
Published: May 2024

AbstractBouillon is a promising candidate for fortification to complement existing large‐scale food fortification (LSFF) programs. We used household dietary data from Burkina Faso to model potential contributions of bouillon fortified with vitamin A (40–250 μg/g bouillon), folic acid (20–120 μg/g), vitamin B12 (0.2–2 μg/g), iron (0.6–5 mg/g), and zinc (0.6–5 mg/g) for meeting micronutrient requirements of women of reproductive age (15–49 years; WRA) and children (6–59 months). Most households (82%) reported bouillon consumption, with higher proportions of resource‐constrained (84–88%) and rural households (88%) consuming bouillon. Accounting for the contributions of existing LSFF, household diets were inadequate to meet the micronutrient requirements of many WRA and children, exceeding 90% and 60% inadequacy for vitamins A and B12, respectively. Modeling results showed bouillon fortification could reduce inadequacy by up to ∼30 percentage points (pp) for vitamin A, ∼26 pp for folate among WRA (∼11 pp among children), ∼38 pp for vitamin B12, and 11–13 pp for zinc, with comparable reductions across socioeconomic strata and urban and rural residence. Predicted reductions in iron inadequacy were <3 pp. These results suggest dietary micronutrient inadequacies are a concern in Burkina Faso, and fortified bouillon can make substantial contributions to reducing micronutrient inadequacies, including among resource‐constrained and rural populations.
Effect of Topical Application of anNSAIDLateral to the Incision on Postoperative Pain Following Unicompartmental Knee Arthroplasty: A Double‐Blind Randomized Controlled Trial
Authors: Li Chao , Li Lei , Li Yifan , Liu Dehua , Han Kaifei , Zhu Ranlyu , Zhao Yao , Lu Qunshan , Li Chunde 
Published: May 2024

ObjectiveHow to minimize postoperative pain following knee replacement surgery has been a great challenge. This study was performed to evaluate the effect of applying a topical nonsteroidal anti‐inflammatory drug (NSAID) lateral to the incision for postoperative pain following unicompartmental knee arthroplasty (UKA).MethodsThe randomized controlled trial enrolled 100 patients from August 2023 to January 2024. One hundred patients who underwent UKA were randomized into two groups. The intervention group received a topical NSAID lateral to the incision postoperatively, and the control group received a placebo lateral to the incision postoperatively. The primary outcome measures were the amount of opioid consumption and the visual analogue scale (VAS) score (12, 24, 36, 48, and 72 h after operation) for pain. The secondary outcome measures were the American Knee Society Score (AKSS, preoperation and 1‐month follow‐up after operation), the time of first analgesic demand, side effects of opioids, operation time, postoperative stay, surgery‐related complications, and postoperative incision healing grade. Independent samplettest and paired samplettest were used to compare continuous data. Chi‐square test and Fisher's precision probability tests were used to analyze the categorical data.ResultsNinety‐eight patients (intervention group, 48 patients; control group, 50 patients) were analyzed. Opioid consumption was significantly lower in the intervention group than in the control group during the first 12 h, 12 to 24 h, and 24 to 48 h postoperatively (p < 0.05). The VAS score for pain within 72 h postoperatively was significantly lower in the intervention group than in the control group (p < 0.05). There was no significant difference in the AKSS, operation time, postoperative stay, complications, or postoperative incision healing grade between the two groups. The time of first analgesic demand for patient‐controlled analgesia was significantly later in the intervention group than in the control group (p < 0.05). There were fewer side effects of opioids in the intervention group (8.3%) than in the control group (18.0%).ConclusionPostoperative application of topical NSAIDs lateral to the incision is an effective and safe method for pain management after UKA, helping to decrease the pain score and reduce opioid consumption postoperatively with no increase in side effects.
Bortezomib for antibody‐mediated rejection of kidney transplant in youth: Associations with donor‐specific antibody
Authors: Fulchiero Rosanna , Galea Lauren , Hewlett Jennifer , Savant Jonathan D. , Lopez Sonya , Amaral Sandra , Viteri Bernarda 
Published: May 2024

AbstractBackgroundAntibody‐mediated rejection is one of the most significant risk factors for allograft dysfunction and failure in children and adolescents with kidney transplants, yet optimal treatment remains unidentified. To date, there are mixed findings regarding the use of Bortezomib, a plasma cell apoptosis inducer, as an adjunct therapy in the treatment of antibody‐mediated rejection.MethodsIn a retrospective single center study, we reviewed the efficacy and tolerability of bortezomib as adjunct therapy for treatment‐refractory antibody‐mediated rejection.ResultsSix patients with a median age of 14.6 years (range 6.9–20.1 years) received bortezomib at a mean of 71 months (range 15–83 months) post‐kidney transplant. Four patients experienced decline in estimated glomerular filtration rate (eGFR) from 4% to 42%. One patient started bortezomib while on hemodialysis and did not recover graft function, and another patient progressed to hemodialysis 6 months after receiving bortezomib. Although DSA did not completely resolve, there was a statistically significant decline in DSA MFI pre and 12‐months post‐BZ (p = .012, paired t‐test) for the subjects who were not on dialysis at the time of bortezomib. Chronic Allograft Damage Index (CADI) score of ≥3 was seen in all six subjects at their biopsy prior to therapy. No adverse effects were reported.ConclusionsBortezomib was well tolerated and resulted in improvements in MFI of DSA among four pediatric subjects without allograft failure, although no effects were observed on eGFR trajectory. Further studies are needed to clarify whether earlier intervention with bortezomib could prevent renal failure progression.
Amoralism in theHanfeizi
Authors: Escoffier Gabrièle 
Published: May 2024

AbstractThis article surveys three possible ways to assess morality in theHanfeizi. The first is the “traditional” outlook, according to which Han Fei disregards all moral considerations in politics. The second acknowledges the presence of moral questions in the text but maintains that it ultimately promotes amoralism as an essential feature of the Legalist state. A (less common) third way is to say that there is a moral core to Han Fei's political philosophy. I will defend the third way, which shifts the perception of theHanfeizifrom a mere manual of political manipulation to a comprehensive ideal vision for the world. This interpretation necessitates a recognition of how political morality can coherently exist alongside an apparent divide between private ethics and political action. This is something that those seeking more systematic forms of ethics in theHanfeizimight overlook.
The association between perceived social functioning and heart rate variability is mediated by subclinical depressive symptomatology and moderated by gender
Authors: Piejka Aleksandra , Thayer Julian F. , Okruszek Łukasz 
Published: May 2024

AbstractChronic loneliness and low perceived social support have been recognized as risk factors for both mental and cardiovascular disorders. It has been proposed that their link to psychophysiological problems may involve changes in parasympathetic activity. However, the exact underlying psychopathological mechanisms and the moderating effects of gender are still not thoroughly examined. Thus, the present study investigated associations between perceived social functioning and resting vagal tone in the context of potential cognitive and subclinical mediators and gender differences. Three hundred twenty‐five young adults (aged 18–35, 180 women) underwent an electrocardiogram measurement of 6‐minute resting heart rate variability (HRV). They also completed questionnaires assessing loneliness, perceived social support, social cognitive biases, depressive and social anxiety symptoms, and general mental health. In men, HRV was significantly and negatively associated with poorer perceived social functioning, depressive symptoms, and self‐reported social cognitive biases, while in women, there was a quadratic link between HRV and depressive symptoms and HRV and general mental health. Moderated mediation analysis revealed that depressive symptoms fully mediated the relationship between perceived social functioning and HRV in men. The results suggest that decreased resting vagal tone in lonely individuals is linked to depressive symptomatology rather than to specific social cognitive biases and that this association is significant only in men.
Bayhead delta succession as a stratigraphic marker of sea‐level changes during the early to late Holocene – the Nakdong valley of south‐eastern Korea
Authors: Hong Seok‐Hwi , Ryang Woo Hun , Yoo Dong‐Geun , Simms Alexander R. , Kim Jin Cheul , Lee Gwang‐Soo 
Published: May 2024

ABSTRACTBayhead deltas form at the interface between fluvial and estuarine systems. As such, they are sensitive to processes operating in both the fluvial catchment and the marine realm, including past relative sea‐level changes. The Nakdong valley is a small and confined incised valley containing a bayhead delta that provides a record of fluvial sediment input and accommodation changes. Based on a facies analysis that included 833 sediment textures and 118 optically stimulated luminescence and radiocarbon ages within five cores up to 70 m long, this study reconstructed the development of a fully filled bayhead delta in response to relative sea‐level changes through the early to late Holocene. Sixteen facies are defined and grouped into eight facies associations: alluvial plain; fluvial channel and floodplain; oxidized fluvial channel; tidal flat; tidal bar; central basin and bayhead prodelta; bayhead delta front; and bayhead delta plain. The sequence stratigraphy of the Nakdong valley fill can be divided into three systems tracts: a lowstand systems tract, a transgressive systems tract and a highstand systems tract. Overall sedimentary analyses suggest six depositional stages corresponding to variations between sediment inputs and sea‐level rise of the developing bayhead delta in the Nakdong valley. The depositional model tracks relative sea‐level rise in the Nakdong valley after 12 ka during the early to late Holocene. These analyses on the Nakdong bayhead delta succession illustrate the balance between sediment inputs and periods of accelerating and decelerating relative sea‐level rise during the Holocene. The architecture of the valley fill also records two abrupt disequilibrium events from 9 to 8 ka and 5 to 3 ka, likely resulting from rapid sea‐level rise during the deglacial outburst flooding of the early Holocene and decreased sediment inputs during regional climatic changes associated with the middle Holocene, respectively.
Using the inverse finite‐element method to harmonise classical modal analysis with fibre‐optic strain data for robust population‐based structural health monitoring
Authors: Delo Giulia , Roy Rinto , Worden Keith , Surace Cecilia 
Published: May 2024

AbstractVibration‐based approaches to structural health monitoring (SHM) gained increasing significance for assessing the behaviour of existing structures because of their non‐intrusive nature and high sensitivity to damage. However, data availability often limits the application of SHM approaches. The population‐based structural health monitoring (PBSHM) theory addresses this challenge, enhancing diagnostic inferences by sharing knowledge across a population of similar structures. In real‐life scenarios, sharing data from distinct structures requires dealing with results obtained with different experimental setups, multiple sensors, input choices and acquisition systems. Therefore, it is crucial to harmonise various features to achieve accurate and reliable results. The present study presents the results of a classic experimental modal analysis (EMA) using scanning laser Doppler vibrometer (SLDV) measurements and a strain‐based EMA conducted using high‐definition distributed fibre‐optic strain sensors. The experimental case study of a laboratory‐scale steel aircraft subjected to specific operating and damage conditions is introduced, allowing for a comprehensive discussion of the features extracted from the two EMA techniques, which can also be generalised to structures within different domains. This research highlights the advantages and limitations of fibre‐optic‐based EMA compared to classic methods, as fibre‐optic strain sensors offer a cost‐effective alternative to accelerometers or SLDV for dynamic testing. Furthermore, the feasibility of employing the inverse finite‐element method (iFEM) in the dynamic domain is investigated. This method can estimate the whole displacement field of a structure from a limited number of strain values, thus harmonising strain measurements with the SLDV measurements. By analysing the features extracted from different EMA techniques within the PBSHM framework, this study contributes to advancing the understanding and application of the PBSHM approach in diverse experimental scenarios, laying the foundation for further investigation of features and adequate methods for sharing damage‐state knowledge across a population of structures.
Soil fungal communities under slash‐and‐burn system in Mozambique: A metataxonomic approach
Authors: Serrani Dominique , Ferrocino Ilario , Garofalo Cristiana , Osimani Andrea , Corvaglia Maria Rita , Milanović Vesna , Aquilanti Lucia , Cardelli Valeria , Salvucci Andrea , Cocco Stefania , Borguete Alves Rafael Rogerio , Corti Giuseppe 
Published: May 2024

AbstractThis study provides a metataxonomic analysis of the fungal communities in soils under slash‐and‐burn agroforestry system and offers new insights into the relationships between fungal populations and soil physicochemical features such as pH, the particle size distribution, easily oxidizable organic carbon, total nitrogen, available phosphorus, and the mineralogical composition. Soils from three locations in central Mozambique—Vanduzi, Sussundenga, and Macate—that are subjected to slash‐and‐burn were considered to assess the effects of the forest fallow length (temporal variation) and of the land use (charcoal kiln, crop field, and forest; meaning horizontal variation) on the fungal community. The fungi of the genetic horizons (vertical variation) were also considered. Most of the detected fungi were decomposers, antagonists of plant pathogens, and plant‐growth promoters; they were differently distributed in relation to the soil's physicochemical properties and the soil use. The variations in the fungi distribution among the locations and between the horizons were considerable, while there were few variations between the different land‐use types. The limited differences between land uses indicate the inability of a forest fallow period shorter than 50 years to improve soil fertility and induce changes in the fungal community. The pedological approach used to identify and sample soil horizons allowed us to clearly distinguish the fungal community of the A horizons, those richest in organics and nutrients, and that of the Bo horizons, which have poor fertility.