bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tropospheric and Stratospheric Boreal Winter Jet Response to Eddying Ocean in a Seasonal Forecast System
Authors: Hirahara S. , Ishikawa I. , Fujii Y. , Nakano H. , Tsujino H. , Adachi Y. , Naoe H. 
Published: June 2024

AbstractUnderstanding the impacts of high‐resolution ocean model provides valuable insights for future research. However, the outcomes of sea surface state changes in both the tropics and mid‐latitudes remain unclear, and initialized seasonal forecasts have not been studied extensively. This study investigates the impact of ocean model resolution with the first long‐term hindcast experiment of an eddy‐resolving (0.1°) ocean model used for global seasonal forecasting. We show that using the high‐resolution ocean model significantly changes boreal winter jet streams in the atmosphere, based on the comparison of 30‐year hindcasts with ocean resolutions ranging from 1° to 0.1° for the Japan Meteorological Agency/Meteorological Research Institute Coupled Prediction System version 3. In boreal winters, the cold sea surface bias in the equatorial Pacific is significantly reduced, leading to an equatorward shift in the intertropical convergence zone (ITCZ) and enhanced convective activity in the western equatorial Pacific. The subtropical jet shifts equatorward due to the ITCZ shift and the weakening of equatorward propagation of mid‐latitude atmospheric eddies. The enhanced convective activity in the tropics has a remote influence in the mid‐latitudes, significantly reducing the upward eddy propagation of zonal wavenumber 1. Sea surface warm‐up in the mid‐latitudes partially cancels the reduction impact by enhancing the zonal wavenumber 2. Overall, the polar night jet accelerates due to the reduced supply of eddy forcing.
Assessing the Fidelity of Landfalling Tropical Cyclone Convective‐Scale Environments in the Warn‐On‐Forecast System Using Radiosondes
Authors: Schenkel Benjamin A. , Jones Thomas , Waugh Sean 
Published: June 2024

AbstractForecasts of tropical cyclone (TC) tornadoes are less skillful than their non‐TC counterparts at all lead times. The development of a convection‐allowing regional ensemble, known as the Warn‐on‐Forecast System (WoFS), may help improve short‐fused TC tornado forecasts. As a first step, this study investigates the fidelity of convective‐scale kinematic and thermodynamic environments to a preliminary set of soundings from WoFS forecasts for comparison with radiosondes for selected 2020 landfalling TCs. Our study shows reasonable agreement between TC convective‐scale kinematic environments in WoFS versus observed soundings at all forecast lead times. Nonetheless, WoFS is biased toward weaker than observed TC‐relative radial winds, and stronger than observed near‐surface tangential winds with weaker winds aloft, during the forecast. Analysis of storm‐relative helicity (SRH) shows that WoFS underestimates extreme observed values. Convective‐scale thermodynamic environments are well simulated for both temperature and dewpoint at all lead times. However, WoFS is biased moister with steeper lapse rates compared to observations during the forecast. Both CAPE and, to a lesser extent, 0–3‐km CAPE distributions are narrower in WoFS than in radiosondes, with an underestimation of higher CAPE values. Together, these results suggest that WoFS may have utility for forecasting convective‐scale environments in landfalling TCs with lead times of several hours.
Changes in Late Pleistocene Dust Activity in the Southern Tibetan Plateau in Response to Orbital Precession and Mountain Glaciers
Authors: Cheng Liangqing , Long Hao , Zhang Zhi , Zhang Jingran , Chen Zhong , Song Yougui , Wu Yubin , Luobu Pingcuo , Yang Linhai , Dong Zhibao 
Published: June 2024

AbstractThe Tibetan Plateau (TP) serves not only as the “water tower” of Asia but also as an important source in the global atmospheric dust cycle. While our knowledge of modern dust activity and its impacts and interactions with climate change in the TP has greatly advanced in the past decades, the emission, transport, and deposition of dust on the geological time scale remains unclear. This study analyzed a 7.6‐m thick sedimentary sequence consisting of loess and sand from the Yarlung Tsangpo River (YTR) valley in the southern TP. The sequence chronology was established using nineteen K‐feldspar post‐infrared infrared stimulated luminescence (pIRIR) ages, which ranged from 47.11 ± 1.95 to 116.65 ± 5.55 ka in a general stratigraphical order. The dust sedimentation rate and sorting coefficient of grain size were used to reflect dust activity and near‐surface wind, respectively. The results indicated that dust activity in the southern TP is mainly regulated by the near‐surface wind intensity and follows the variation pattern of precession, although the waxing and waning of mountain glaciers also affect the amplitude of dust activity. This pattern is not consistent with the Greenland dust record, which follows the variation pattern of obliquity. Therefore, dust accumulation in the southern TP is concluded to be primarily controlled by the South Asian winter monsoon (SAWM) forced by precession, whereas dust accumulation in Greenland is closely related to the intensity of the high‐level westerlies forced by obliquity.
The Representation of Convectively Coupled Kelvin Waves in Simulations With Modified Wave Amplitudes
Authors: Lawton Q. A. , Rios‐Berrios R. , Majumdar S. J. , Emerton R. , Magnusson L. 
Published: June 2024

AbstractConvectively coupled Kelvin waves (CCKWs) are important drivers of tropical weather and may influence extreme rainfall and tropical cyclone formation. However, directly attributing these impacts to CCKWs remains a challenge. Numerical models also struggle to simulate the convective coupling of CCKWs. To address these gaps in understanding, this study examines a set of global simulations in which CCKW amplitudes are modified in the initial conditions. The Model for Prediction Across Scales –Atmosphere is used to simulate a time period in which several CCKWs coexisted around the globe, including an unusually strong CCKW located over the Atlantic. Prior to running the simulation, Kelvin‐filtered fields are identified in initial conditions and used to either amplify or dampen the initial wave amplitude. This method is effective at robustly changing the strength and structure of simulated CCKWs and can illuminate their convective coupling. Rainfall intensity within simulated CCKWs is shown to be partially controlled by column saturation fraction and deep convective inhibition. Despite the accurate depiction of most CCKWs during this time period, however, these experiments fail to simulate convective coupling in the strong Atlantic CCKW. This is true even after amplifying this wave at initialization. The cause of this failure is unclear and motivates additional work into the modeling and predictability of CCKW events. Overall, this study demonstrates that modifying CCKW amplitudes can serve as a useful tool for understanding CCKWs. This method may also be useful for future attributional work on the influence of CCKWs on other phenomena.
Influence of Farallon Slab Loading on Intraplate Stress and Seismicity in Eastern North America in the Presence of Pre‐Existing Weak Zones
Authors: Hightower Erin , Gurnis Michael , Mao Wei 
Published: June 2024

AbstractDespite the stability of the continental interior, eastern North America has hosted many significant historical earthquakes. Seismicity concentrates within tectonically inherited structures, which can act as weak zones where stress accumulates. Within these zones, systematic stress rotations may be explained by long‐wavelength sources. We test the hypothesis that mantle‐flow driven by the Farallon slab contributes to intraplate seismicity via the reactivation of pre‐existing faults. We model the stress field using seismically constrained global high‐resolution finite‐element flow models with CitcomS. To isolate the slab's effect, we vary its buoyancy between a case of neutrality and a case with full negative thermal buoyancy derived from tomography. Low‐viscosity lithospheric weak zones located at failed rifts, loaded by a mass anomaly at depth, transmit elevated stresses to the overlying crust. The sinking of the Farallon slab drives localized mantle flow beneath the central‐eastern US, generating a large stress amplification of 100–150 MPa peaking over the New Madrid Seismic Zone (NMSZ). This stress amplification exerts a continent‐wide clockwise rotation on the stress field, which in the presence of weak zones reproduces some observed deviations of the seismically inferred SHmax from the regional borehole SHmax, bringing optimally oriented faults, closer to failure, some of which are associated with major historical earthquakes, including the Reelfoot Fault in the NMSZ and the Timiskaming Fault in Western Quebec. However, stronger lithospheric viscosity gradients, shallower weak zones, or weaker faults are still needed to fully reproduce the observed stress field in some areas.
Multi‐Year Potential Predictability of the Wintertime Heavy Precipitation Potentials in East Asia
Authors: Mochizuki Takashi 
Published: June 2024

AbstractWe validate the multiyear potential predictability of wintertime heavy precipitation potential in East Asia by combining initialized decadal hindcasts of the global climate model and large ensemble simulations from a high‐resolution global atmospheric model. By analyzing a set of initialized hindcasts, the major predictive components of sea surface temperature (SST) variability beyond interannual timescales are identified as high‐latitudes multidecadal variability and the so‐called trans‐basin variability (TBV). A set of 100 ensemble simulations using a high‐resolution atmospheric model showed a significantly large signal‐to‐noise ratio for the wintertime heavy precipitation potential in East Asia, which is closely related to the TBV. When the SST around the maritime continent is higher, the anomalously low pressure in the northwestern Pacific enhances low‐level cold air transport due to the winter monsoon. Consequently, the resultant weaker baroclinicity in the lower atmosphere reduces storm activity and wintertime heavy precipitation potential in East Asia.
Modeling the Impacts of Volatile Chemical Product Emissions on Atmospheric Photochemistry and Ozone Formation in Los Angeles
Authors: Chen Tianshu , Gilman Jessica , Kim Si‐Wan , Lefer Barry , Washenfelder Rebecca , Young Cora J. , Rappenglueck Bernhard , Stevens Philip S. , Veres Patrick R. , Xue Likun , de Gouw Joost 
Published: June 2024

AbstractThe dominant fraction of anthropogenic volatile organic compound (VOC) emissions shifted from transportation fuels to volatile chemical products (VCP) in Los Angeles (LA) in 2010. This shift in VOC composition raises the question about the importance of VCP emissions for ozone (O3) formation. In this study, O3 chemistry during the CalNex 2010 was modeled using the Master Chemical Mechanism (MCM) version 3.3.1 and a detailed representation of VCP emissions based on measurements combined with inventory estimates. The model calculations indicate that VCP emissions contributed to 23% of the mean daily maximum 8‐hr average O3 (DMA8 O3) during the O3 episodes. The simulated OH reactivity, including the contribution from VCP emissions, aligns with observations. Additionally, this framework was employed using four lumped mechanisms with simplified representations of emissions and chemistry. RACM2‐VCP showed the closest agreement with MCM, with a slight 4% increase in average DMA8 O3 (65 ± 13 ppb), whereas RACM2 (58 ± 13 ppb) and SAPRC07B (59 ± 14 ppb) exhibited slightly lower levels. CB6r2, however, recorded reduced concentrations (37 ± 10 ppb). Although emissions of O3 precursors have declined in LA since 2010, O3 levels have not decreased significantly. Model results ascribed this trend to the rapid reduction in NOX emissions. Moreover, given the impact of COVID‐19, an analysis of 2020 reveals a shift to a NOX‐limited O3 formation regime in LA, thereby diminishing the influence of VCPs. This study provides new insights into the impact of VCP emissions on O3 pollution from an in‐depth photochemical perspective.
Synoptic Variability in the Tropical Oceanic Moist Margin
Authors: Robinson C. M. , Narsey S. , Jakob C. 
Published: June 2024

AbstractRecent research has described a ‘moist margin’ in the tropics, defined through a total column water vapor (TCWV) value of 48 kg m−2, that encloses most of the rainfall over the tropical oceans. Diagnosing the moist margin in the ERA5 reanalysis reveals that it varies particularly on synoptic time scales, which this study aims to quantify. We define ‘wet and dry perturbation’ objects based on the margin's movement relative to its seasonal climatology. These perturbations are associated with a variety of synoptic weather systems. Wet (dry) perturbations produce substantially more (less) rainfall compared to the seasonal average, confirming the clear link between moisture and precipitation. On synoptic scales we suggest that mid‐tropospheric humidity plays a key role in creating these perturbations, while sea surface temperatures (SSTs) are relatively unimportant.
Obesity, psychological well-being related measures, and risk of seven non-communicable diseases: evidence from longitudinal studies of UK and US older adults
Authors: Putra I Gusti Ngurah Edi , Daly Michael , Sutin Angelina , Steptoe Andrew , Scholes Shaun , Robinson Eric 
Published: June 2024

Abstract
Background
We examined the role of psychological well-being related measures in explaining the associations between obesity and increased risk of non-communicable diseases (NCDs: hypertension, heart disease, stroke, diabetes, arthritis, cancer, and memory-related disease) in older adults.

Methods
Data were from the English Longitudinal Study of Ageing (ELSA), UK (baseline: Wave 4—2008/2009; n = 8127) and the Health and Retirement Study (HRS), US (baseline: Waves 9 and 10—2008/2010; n = 12,477). Objective body mass index was used to define obesity. A range of psychological well-being related measures (e.g., depressive symptoms, life satisfaction) was available in ELSA (n = 7) and HRS (n = 15), and an index of overall psychological well-being was developed separately in each study. NCDs were from a self-reported doctor diagnosis and/or other assessments (e.g., biomarker data) in both studies; and in ELSA, NCDs from linked hospital admissions data were examined. Longitudinal associations between obesity status, psychological well-being measures, and NCDs were examined using Cox proportional hazard models (individual NCDs) and Poisson regression (a cumulative number of NCDs). Mediation by psychological well-being related measures was assessed using causal mediation analysis.

Results
Obesity was consistently associated with an increased prospective risk of hypertension, heart disease, diabetes, arthritis, and a cumulative number of NCDs in both ELSA and HRS. Worse overall psychological well-being (index measure) and some individual psychological well-being related measures were associated with an increased prospective risk of heart disease, stroke, arthritis, memory-related disease, and a cumulative number of NCDs across studies. Findings from mediation analyses showed that neither the index of overall psychological well-being nor any individual psychological well-being related measures explained (mediated) why obesity increased the risk of developing NCDs in both studies.

Conclusion
Obesity and psychological well-being may independently and additively increase the risk of developing NCDs.
Relationships between minerals’ intake and blood homocysteine levels based on three machine learning methods: a large cross-sectional study
Authors: Fan Jing , Liu Shaojie , Wei Lanxin , Zhao Qi , Zhao Genming , Dong Ruihua , Chen Bo 
Published: June 2024

Abstract
Background
Blood homocysteine (Hcy) level has become a sensitive indicator in predicting the development of cardiovascular disease. Studies have shown an association between individual mineral intake and blood Hcy levels. The effect of mixed minerals’ intake on blood Hcy levels is unknown.

Methods
Data were obtained from the baseline survey data of the Shanghai Suburban Adult Cohort and Biobank(SSACB) in 2016. A total of 38273 participants aged 20–74 years met our inclusion and exclusion criteria. Food frequency questionnaire (FFQ) was used to calculate the intake of 10 minerals (calcium, potassium, magnesium, sodium, iron, zinc, selenium, phosphorus, copper and manganese). Measuring the concentration of Hcy in the morning fasting blood sample. Traditional regression models were used to assess the relationship between individual minerals’ intake and blood Hcy levels. Three machine learning models (WQS, Qg-comp, and BKMR) were used to the relationship between mixed minerals’ intake and blood Hcy levels, distinguishing the individual effects of each mineral and determining their respective weights in the joint effect.

Results
Traditional regression model showed that higher intake of calcium, phosphorus, potassium, magnesium, iron, zinc, copper, and manganese was associated with lower blood Hcy levels. Both Qg-comp and BKMR results consistently indicate that higher intake of mixed minerals is associated with lower blood Hcy levels. Calcium exhibits the highest weight in the joint effect in the WQS model. In Qg-comp, iron has the highest positive weight, while manganese has the highest negative weight. The BKMR results of the subsample after 10,000 iterations showed that except for sodium, all nine minerals had the high weights in the joint effect on the effect of blood Hcy levels.

Conclusion
Overall, higher mixed mineral’s intake was associated with lower blood Hcy levels, and each mineral contributed differently to the joint effect. Future studies are available to further explore the mechanisms underlying this association, and the potential impact of mixed minerals’ intake on other health indicators needs to be further investigated. These efforts will help provide additional insights to deepen our understanding of mixed minerals and their potential role in health maintenance.
Serum albumin and white matter hyperintensities
Authors: Zahr Natalie M. , Pfefferbaum Adolf 
Published: June 2024

AbstractPeople living with HIV and those diagnosed with alcohol use disorders (AUD) relative to healthy individuals commonly have low levels of serum albumin, substantiated as an independent predictor of cardiovascular events. White matter hyperintensities (WMH)—a neuroimaging feature of cerebral small vessel disease—are also related to cardiovascular disease. Despite consensus regarding associations between high levels of urine albumin and WMH prevalence, and low serum albumin levels and impaired cognitive functioning, relations between serum albumin and WMH burdens have rarely been evaluated. Here, a sample including 160 individuals with AUD, 142 living with HIV, and 102 healthy controls was used to test the hypothesis that serum albumin would be inversely related to WMH volumes and directly related to cognitive performance in the two diagnostic groups. Although serum albumin and periventricular WMH volumes showed an inverse relationship in both AUD and HIV groups, this relationship persisted only in the HIV group after consideration of traditional cardiovascular (i.e., age, sex, body mass index (BMI), nicotine use, hypertension, diabetes), study-relevant (i.e., race, socioeconomic status, hepatitis C virus status), and disease-specific (i.e., CD4 nadir, HIV viral load, HIV duration) factors. Further, serum albumin contributed more significantly than periventricular WMH volume to variance in performance on a verbal learning and memory composite score in the HIV group only. Relations in both HIV and AUD groups between albumin and hematological red blood cell markers (e.g., hemoglobin, hematocrit) suggest that in this sample, serum albumin reflects hematological abnormalities. Albumin, a simple serum biomarker available in most clinical settings, may therefore help identify periventricular WMH burden and performance levels in specific cognitive domains in people living with HIV. Whether serum albumin contributes mechanistically to periventricular WMH in HIV will require additional investigation.
Inflammation and immune system pathways as biological signatures of adolescent depression—the IDEA-RiSCo study
Authors: Zonca Valentina , Marizzoni Moira , Saleri Samantha , Zajkowska Zuzanna , Manfro Pedro H. , Souza Laila , Viduani Anna , Sforzini Luca , Swartz Johnna R. , Fisher Helen L. , Kohrt Brandon A. , Kieling Christian , Riva Marco Andrea , Cattaneo Annamaria , Mondelli Valeria 
Published: June 2024

AbstractThe biological mechanisms underlying the onset of major depressive disorder (MDD) have predominantly been studied in adult populations from high-income countries, despite the onset of depression typically occurring in adolescence and the majority of the world’s adolescents living in low- and middle-income countries (LMIC). Taking advantage of a unique adolescent sample in an LMIC (Brazil), this study aimed to identify biological pathways characterizing the presence and increased risk of depression in adolescence, and sex-specific differences in such biological signatures. We collected blood samples from a risk-stratified cohort of 150 Brazilian adolescents (aged 14–16 years old) comprising 50 adolescents with MDD, 50 adolescents at high risk of developing MDD but without current MDD, and 50 adolescents at low risk of developing MDD and without MDD (25 females and 25 males in each group). We conducted RNA-Seq and pathway analysis on whole blood. Inflammatory-related biological pathways, such as role of hypercytokinemia/hyperchemokinemia in the pathogenesis of influenza (z-score = 3.464, p < 0.001), interferon signaling (z-score = 2.464, p < 0.001), interferon alpha/beta signaling (z-score = 3.873, p < 0.001), and complement signaling (z-score = 2, p = 0.002) were upregulated in adolescents with MDD compared with adolescents without MDD independently from their level of risk. The up-regulation of such inflammation-related pathways was observed in females but not in males. Inflammatory-related pathways involved in the production of cytokines and in interferon and complement signaling were identified as key indicators of adolescent depression, and this effect was present only in females.
Mechanism and role of nuclear laminin B1 in cell senescence and malignant tumors
Authors: Lv Tingcong , Wang Cong , Zhou Jialin , Feng Xiao , Zhang Lijun , Fan Zhe 
Published: June 2024

AbstractNuclear lamin B1 (LMNB1) is a member of the nuclear lamin protein family. LMNB1 can maintain and ensure the stability of nuclear structure and influence the process of cell senescence by regulating chromatin distribution, DNA replication and transcription, gene expression, cell cycle, etc. In recent years, several studies have shown that the abnormal expression of LMNB1, a classical biomarker of cell senescence, is highly correlated with the progression of various malignant tumors; LMNB1 is therefore considered a new potential tumor marker and therapeutic target. However, the mechanism of action of LMNB1 is influenced by many factors, which are difficult to clarify at present. This article focuses on the recent progress in understanding the role of LMNB1 in cell senescence and malignant tumors and offers insights that could contribute to elucidating the mechanism of action of LMNB1 to provide a new direction for further research.