bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Development and Performance of a Gemini Viscoelastic Surfactant with Tricationic Groups Applied in Unconventional Oil and Gas Reservoir Stimulation
Authors: Zhang Wenlong , Mao Jincheng , Yang Yun , Chai Huiqiang , Shuang Zhiqiang , Wang Lan , Yang Xiaojiang , Wang Longyao 
Published: June 2024

AbstractTo improve water solubility and salt tolerance of viscoelstic surfactants (VESs), modifying the spacer of Gemini VES was adopted and a novel Gemini VES nominated TC‐2OH, with tri‐cationic groups and double hydroxyls on the spacer, was developed. The basic surface activity properties of TC‐2OH and the molecular aggregate behavior stimulated by NaCl or NaSal were measured and analyzed to investigate the mechanism of viscoelastic fluid forming by TC‐2OH solution, and it proved that TC‐2OH is more sensitive to NaSal, compared with NaCl, due to the embedded structure of salicylate. The molecular structure of TC‐2OH imparts excellent solubility to itself, and with the assistance of ethanol, the dissolution time in water can be shortened to within 45 seconds. In addition, oscillation experiments, heat and shear resistant experiments, and drag reduction tests were conducted to study the advantage of NaSal for stimulating the formation of the slickwater compared with NaCl. The slickwater stimulated by NaSal indeed exhibit superior drag reduction and proppant carrying capacity. To effectively disassemble the wormlike micelles for gel breaking, ethylene glycol butyl ether performs better than the hydrocarbons because of its high polarity and water solubility. The gel breaking fluids of slickwater caused extremely low damage to the tight sandstone cores. The successful development of TC‐2OH enables instant preparation of slickwater and variable‐viscosity for fracturing in unconventional reservoirs, which also realizes convenient switching between the slickwater with different viscosity.
Investigating the Removal Efficiency of Fenton Reaction for Drugs in Municipal Wastewater
Authors: Bai Song , Wang Fang , Liu Shan , Chen Yuemeng , Li Miao , Liu Lin , Xu Shunyi , Xu Jing 
Published: June 2024

AbstractDrugs and their metabolites have become new types of pollutants, the presence of which constitutes a serious environmental problem. This article applies the established LC–MS/MS method to investigate the removal efficiency of different ratios of Fenton reagents for common drugs in wastewater. The results showed that the linearity of the 10 common drugs was good in the dynamic range of 1–100 ng/L, and the R2>0.99. The LODs and LOQs ranged from 0.01–0.443 ng/L and 0.04–1.44 ng/L, respectively. The average relative recoveries ranged from 72.99–117 %. In addition, considering the economic and application effects of chemical reagents, the optimal test dose of H2O2 in Fenton reagent was determined to be 12.5 mL. This experiment provides a simple, rapid and low‐cost LC–MS/MS method for the detection of drugs in wastewater. It also provides data reference for effective management of drug production sites and domestic wastewater pollution.
Electrochemiluminescence Sensor Based on TPEA‐RuMOF: For Highly Selective and Sensitive Detection of Copper Ions
Authors: Shuai Hai , Cui Hanfeng , Zhang Jie , Hu Huiting , Long Qian , Yin Xiaocui , Liao Fusheng , Fan Hao , Liu Zhiqiang , Wu Bo 
Published: June 2024

AbstractIn this study, we present the novel combination of AE‐TPEA with RuMOF to construct an electrochemiluminescence (ECL) sensor using a TPEA‐RuMOF composite material specifically for copper ions (Cu2+) detection. Using K2S2O8 as a co‐reactant, we explored the ECL behavior of the TPEA‐RuMOF modified electrode, enabling the quantitative detection of Cu2+. Remarkably, this sensor exhibited a wide linear range from 1×10−5 to 1×10−9 M (R2=0.998) and boasted a detection limit as low as 0.41 nM, which is considerably below the EPA (Environmental Protection Agency) permissible copper ion concentration in drinking water of <1.3 mg/L. our synthesized probe offers enhanced stability and selectivity in copper ion detection. This indicates its considerable potential for high‐performance copper ion detectors. We further validated the analytical applicability of this sensor using river water samples.
Farnesol‐Imprinted Nanospheres (FINs) as Quorum Sensing Modulators of Candida albicans Hyphae Formation
Authors: Kachenton Supicha , Nantasenamat Chanin , Piacham Theeraphon 
Published: June 2024

AbstractCandida albicans (C. albicans) produces farnesol as a quorum sensing molecule that suppresses its filamentation. In this study, we synthesized farnesol‐imprinted nanospheres (FINs) to investigate their impact on the morphogenic transition of C. albicans, a fungus known for its pathogenicity in superficial and systemic candidiasis. FINs, synthesized for this purpose, exhibited a significantly higher binding capacity for farnesol compared to control polymers, with a 6.5‐fold increase observed. These polymers displayed a spherical morphology with diameters ranging from 500–700 nm. Treatment with FINs resulting in an increase in hyphae formation in C. albicans, indicating effective capture farnesol by the FINs. This increase in hyphae formation corresponded to a suppressed yeast form of the fungus. Consequently, FINs hold promise as a potential compound to mitigate the severity of disseminated candidiasis by depleting yeast forms. Interestingly, pre‐incubated of FINs with 0.1 mM of farnesol led to a reduction in C. albicans filamentation. This finding suggests that FINs have the capability to adsorb and release farnesol. Therefore, FINs could serve as a delivery agent for farnesol, offering protection against C. albicans filamentation. Overall, the synthesis of FINs presents a promising approach to combating C. albicans infection, whether by reducing disseminated candidiasis or preventing fungal superficial localization.
Linear Free Energy Analysis on the Ring‐Expansion of Arylthiiranes with Ketenes
Authors: Wang Yinqiao , Xu Jiaxi 
Published: June 2024

AbstractThe ring‐expansion of arylthiiranes and phenoxyacetyl chloride was performed in the presence of triethylamine and provided a novel strategy for the synthesis of 4,5‐dihydrobenzo[d]thiepin‐2(1H)‐ones, benzo[d]‐ϵ‐thiolactones, directly without catalysts or additives. Its linear free energy analysis was conducted on the basis of competitive experiments. The results indicate that both reaction constants are close to zero (0.14 for σm and 0.20 for σp), supporting the proposed sulfur‐shifted ene mechanism. The current reaction features atom and step‐economic one‐pot characteristic via a tandem sequence of in situ ketene generation, sulfur‐shifted ene reaction, and aromatization.
Synthesis, Characterization, and Evaluation of Tetrazole Derivatives with Pyrrole‐2,5‐Dione Moieties as Urease Inhibitors: Exploring Structure‐Activity Relationships and Computational Insights
Authors: Muhammed Aziz Dara , Ali Hassan Sangar 
Published: June 2024

AbstractA series of Tetrazole derivatives containing pyrrole‐2,5‐dione groups (5 a–e) were synthesized and comprehensively characterized using HRMS, FT‐IR, and 1H−, 13C‐NMR spectroscopic techniques. These compounds were evaluated for their ability to inhibit urease activity in vitro, demonstrating remarkable inhibitory potential with IC50 values ranging from 4.325±1 to 18.28±1 μM, surpassing the standard thiourea (IC50=17.386±1 μM). Notably, compounds 5 b (IC50=4.325±1 μM), 5 e (IC50=7.411±1 μM), 5 c (IC50=9.313±1 μM), and 5 a (IC50=10.46±1 μM) exhibited notably higher activity compared to the standard thiourea. In our exploration of the structure‐activity relationship (SAR), we investigated the impact of differently substituted aryl rings on inhibitory potential. Our results highlight the crucial role of substituent positioning on the aryl ring, independent of the nature of the substituents. Additionally, computational studies were conducted on all compounds, supporting our experimental findings. Molecular docking simulations revealed a strong correlation between biological evaluation results and computational predictions, affirming the promising inhibitory activity of the compounds.
A Facile Synthesis of Photocatalytic Fe(OH)3 Nanoparticles for Degradation of Phenol
Authors: Kayhan Mehmet , Aksoy Mehmet , Kayhan Emine 
Published: June 2024

AbstractIron hydroxide (Fe(OH)3) nanoparticles have garnered considerable attention for their effectiveness in water treatment. This paper reviews recent studies on the photocatalytic degradation of phenol using Fe(OH)3, detailing the synthesis procedure, photocatalytic reaction conditions under UV‐C and catalyst amount optimization. Iron hydroxide was synthesized using a facile precipitation method, and the produced catalyst was thoroughly characterized using XRD, FTIR, UV‐DRS, DTA/TGA and SEM. Characterization results indicated that the catalyst exhibited very low crystallinity, a 1.84 eV band gap, and very small particle sizes. The study investigated the degradation performance of phenol for different amounts of iron hydroxide, ranging from 0.1 g to 1 g, and determined the optimum catalyst amount to be 0.7 g. The catalyst demonstrated a degradation efficiency for phenol exceeding 90 % at the end of a 180 minute photocatalytic reaction. The paper offers a comprehensive analysis of Fe(OH)3 as a photocatalyst for phenol degradation, highlighting its potential for future applications in water treatment.
Imidazolidinones Derivatives As Pioneering Anticancer Agents: Unraveling Insights Through synthesis And Structure‐Activity Exploration
Authors: Dewangan Smriti , Rawat Varsha , Singh Thakur Alok 
Published: June 2024

AbstractImidazolidinone derivatives have emerged as promising anticancer agents, captivating the attention of researchers in medicinal chemistry. Imidazolidinones, characterized by their unique chemical structure, have demonstrated versatility in synthetic methodologies. Researchers have developed a variety of derivatives, each with distinct modifications, allowing for fine‐tuning of pharmacological properties. This review explores the journey of imidazolidinone compounds, from synthesis to structure‐activity exploration, and investigates their anticancer mechanistic pathways. The synthesis methodologies, including diverse approaches and reaction conditions, were examined. Structural modifications are discussed, showing the versatility sof imidazolidinone scaffolds. Mechanistic insights into their anticancer mechanisms, in vitro, ex‐vivo and in vivo activities, with their challenges in development are critically analyzed. This paper concludes by emphasizing the potential of imidazolidinone derivatives and suggesting future research directions in the pursuit of novel and effective anticancer therapeutics.
Quercetin Nanoparticles as a Promising Intervention against Ethion‐Induced Hepatic Damage in Wistar Albino Rats.
Authors: D Ranjith , AG Telang , S Sandhya , M Karikalan , Kumar Sharma Gaurav , CL Madhu , Kumar Dinesh 
Published: June 2024

AbstractThe current study investigated the therapeutic potential of quercetin and quercetin nanoparticles in alleviating liver toxicity induced by ethion in Wistar albino rats. Quercetin nanoparticles were synthesized using the ionic‐gelation method. Rats were exposed to ethion alone (at high and low doses) or in combination with quercetin or quercetin nanoparticles. Ethion exposure led to significant decreases in organ weight, along with elevated levels of glucose, triglycerides, total cholesterol, low‐density lipoprotein, and acid phosphatase, and reduced high‐density lipoprotein in serum. Hepatocellular biomarker enzymes were increased in the ethion‐exposed group, while antioxidant enzyme levels were decreased. Histopathological analysis revealed fatty changes, degeneration, and hemorrhages in the liver. Co‐administration of quercetin nanoparticles mitigated these effects, potentially by neutralizing reactive oxygen species generated by ethion. Molecular docking studies suggested a strong interaction between quercetin and Cyp2E1, implicating a role in detoxification. This study highlights the potential of nanoquercetin as a therapeutic supplement for pesticide intoxication management.
Electrochemical Determination of Anti‐Cancer Drug Dabrafenib with High Sensitivity Using Multi‐Walled Carbon Nano Tubes Modified Glassy Carbon Electrode
Authors: Mete Cihat , Talay Pınar Pınar 
Published: June 2024

AbstractDabrafenib (DAB) is an organofluor compound and a protein kinase inhibitor used as the mesylate salt in the treatment of metastatic melanoma. For the first time, the electrochemical investigation of the anticancer drug DAB in human serum was conducted using a glassy carbon electrode modified with multi‐walled carbon nanotubes (MWCNTs), employing cyclic voltammetry and square wave voltammetry (SWV) techniques. Electrochemical impedance spectroscopy, cyclic voltammetry, and scanning electron microscopy (SEM) techniques were utilized to analyze the surface morphology and structure of the MWCNT/GC electrode. In the proposed method using optimized experimental conditions, two different linearities were obtained for DAB in the concentration range of 0.04–0.8 μM and 1.0–10.0 μM. The LOD value obtained is 0.014 μM. In this study, the resulting electrochemical sensor was applied for the first time to investigate the electrochemical behavior of DAB with high sensitivity and reproducibility, as well as the possible electrochemical oxidation mechanism.
An Ammonia Gas Sensor Based on Reduced Graphene Oxide Nanocomposite Hydrogels
Authors: Saleh Asala M. , Albiss Borhan A. , Al‐Rawashdeh Nathir A. F. , Alsharaeh Edreese H. 
Published: June 2024

AbstractA flexible gas sensor based on nanocomposite has been developed and characterized for detecting ammonia gas (NH3) in the atmosphere. This sensor utilizes nanocomposite hydrogels composed of Arabic gum (AG), acrylic acid (AAc), reduced graphene oxide (RGO), and silver nanoparticles (AgNPs). Various techniques, including FTIR (Fourier Transform Infrared Spectroscopy), AFM (Atomic Force Microscopy), XRD (X‐ray Diffraction), SEM (Scanning Electron Microscopy), XRF (X‐ray Fluorescence), TGA (Thermo‐gravimetric Analysis), DSC (Differential Scanning Calorimetry), were used to evaluate the sensor‘s properties. The nanocomposite hydrogels showed exceptional swelling ability (597 %), advantageous for accommodating gas molecules like NH3. The Polymerization and network formation percentages of 31 % and 56 %, respectively, suggest a robust hydrogel matrix structure. When tested for NH3 gas sensing at room temperature, the RGO/AgNPs/AGPAAc‐hydrogel exhibited high sensitivity and stability compared to other variants across gas concentrations ranging from 0 to 100 ppm. The improved performance of the physiochemical properties of the nanocomposite hydrogels might be attributed to the combined effect of AgNPs and RGO, which likely enhance sensitivity and stability. Selectivity tests conducted for three gases at room temperature revealed that the sensor response was highly selective to NH3 at a concentration of 50 ppm. Furthermore, the sensor demonstrated consistent performance over time. These findings suggest potential applications in environmental monitoring and industrial safety, with the possibility of contributing to advancements in gas sensing technology and addressing environmental and safety concerns.
Synthesis and Evaluation of Copper Oleate Nanoparticles Against Citrus Anthracnose Caused by Colletotrichum gloeosporioides: In Situ Experiments, In Vitro Bioassays, and Field Trials
Authors: Le The Tam , Nguyen Hoa Du , Ho Dinh Quang , Phan Thi Hong Tuyet , Tran Phuong Chi , Dinh Thi Truong Giang , Le Thi Thu Hiep , Ho Thi Nhung , Nguyen Thi Tam , Tran Lam Dai , Le Dang Quang 
Published: June 2024

AbstractAnthracnose in citrus is a severe disease caused by Colletotrichum species. Synthetic fungicides have been used to combat this citrus disease; however, they may have adverse health effects on humans and cause harmful environmental impacts. During a search for environmentally friendly fungicides, we successfully prepared organic copper (copper (II) oleate) nanoparticles by using natural chitosan polymer as a coating agent and stabilizer and by combining an exchange reaction and in situ coating method. Organic copper nanoparticles coated with chitosan polymer (Cu‐oleate@CS NPs) with Cu contents ranged from 5.0 to 6.0 % by weight. The nanoparticles have an average particle size ranging from 50 nm to 60 nm (TEM), covered by a layer of polymer with a thickness of about 10 to 12 nm. The analytical results of zeta potential and dynamic solution size showed that the nanoparticles are uniformly dispersed (90–120 nm by DLS), with high stability (zeta potential=−61.7 mV) and low cytoxicity to Vero healthy cell line. Cu‐oleate@CS NPs significantly inhibited the mycelial growth of C. gloeosporioides in vitro at 500 and 1000 μg/mL. In field trials, the best antifungal efficacy of Cu‐oleate@CS NPs against citrus anthracnose on orange plants was found at a spray concentration of 0.33 % with a disease control efficacy of 54.18 % at 14 days after the second spraying. Our study results demonstrated a novel preparation of Cu‐oleate@CS NPs and suggested that it could be used as a promising nanoformulation to control citrus anthracnose in vitro and in vivo.
Copper Catalyzed Heteroannelation Reaction between 4‐Thiazolidinones and O‐Acetyl Oximes to Synthesize 2,5‐Diphenyl‐3‐(Pyrimidin‐2‐yl)‐3,4‐Dihydro‐2H‐Pyrrolo‐[2,3‐d]‐Thiazole
Authors: Patel Parth P. , Chikhalia Kishor H. 
Published: June 2024

AbstractAn intermolecular copper catalyzed heteroannelation reaction using Csp3‐Csp3 radical coupling approach has been accomplished to synthesize 2,5‐diphenyl‐3‐(pyrimidin‐2‐yl)‐3,4‐dihydro‐2H‐pyrrolo[2,3‐d]thiazole. C−C coupling between 4‐thiazolidinones and O‐acetyl oximes under Cu catalyst further cyclizes to get the target molecule thiazolidine‐fused nucleus. This unified method offers access to novel fused heterocycles with pyrimidines bearing 4‐thiazolidinone in moderate to higher yields. The optimization study includes various copper catalysts, oxidants, bases and solvents at different temperatures.
Microstructure‐Assisted Wafer‐Scale Fabrication of Perovskite Microlaser Arrays
Authors: Tan Yike , Yang Liuli , Song Hao , Huang Ming , Huang Jianhua , Ali Wajid , Li Fubin , Li Ziwei 
Published: June 2024

AbstractAll inorganic lead halide perovskites exhibit fascinating optical and optoelectronic characteristics for on‐chip lasing, but the lack of precise control of wafer‐scale fabrication for perovskite microstructure arrays restricts their potential applications in on‐chip‐integrated devices. In this work, a microstructure‐template assisted crystallization method is demonstrated via a designed chemical vapor deposition process, achieving the controllable fabrication of homogeneous perovskite micro‐hemispheroid (PeMH) arrays spanning the entire surface area of a 4‐inch wafer. Benefiting from the low‐loss whispering gallery resonance and plasmon‐enhanced light‐matter interactions in well‐confined hybrid cavities, this CsPbX3/Ag (X = Cl, Br) plasmonic microlasers exhibit quite low thresholds below 10 µJ cm−2. Interestingly, these thresholds can be efficiently modulated through the manipulation of plasmonic resonance and electromagnetic field mode in PeMHs owning various diameters. This strategy not only provides a valuable methodology for the large‐scale fabrication of perovskite microstructures but also endorses the potential of all‐inorganic perovskite nanostructures as promising candidates for on‐chip‐integrated light sources.
SISS‐CSA: Secret image sharing scheme with ciphertext‐based share authentication for malicious model
Authors: Bhat Krishnaraj , Jinwala Devesh C. , Prasad Yamuna , Zaveri Mukesh A. 
Published: June 2024

AbstractWe propose a novel secret image sharing scheme with ciphertext‐based share authentication (SISS‐CSA) for sharing grayscale and color secret images in the malicious model. In SISS‐CSA, the dealer and each participant, individually acting as a combiner, can identify each invalid share received from the malicious participant(s) before using it to reconstruct the secret image. This capability, which most comparable schemes lack, prevents reconstructing an incorrect secret image. In SISS‐CSA, the asymptotic time complexities of operations executed by the dealer in the shares generation phase and executed by each combiner in the secret image reconstruction phase are and , respectively. Here, is the number of grayscale values in the secret image, is the number of generated shares, and is the threshold number of shares required for reconstructing the secret image. These asymptotic time complexities and the size of additional information each combiner stores for identifying invalid share(s) are comparatively lesser than those in the state‐of‐the‐art schemes. Furthermore, we obtain a maximum of reduction in the size of additional information each combiner stores for share authentication using the ciphertext‐based share authentication compared to using the standard SHA‐256. To the best of our knowledge, none of the related share authentication approaches achieves this much reduction. We prove the properties of SISS‐CSA using theoretical analysis. We also provide experimental results validating the implications of theoretical analysis corresponding to asymptotic time complexities and the random nature of shares.
Habitat associations of the Rio Grande Silvery Minnow, an endangered desert river fish, from a retrospective analysis based on a period of high abundance
Authors: Dudley Robert K. , Platania Steven P. , Mortensen Jacob G. 
Published: June 2024

Abstract

Objective
Characterizing habitat associations is useful to aid in understanding the habitat requirements of native fishes, particularly those of conservation concern. Our study objective was to characterize mesoscale habitat associations of the only remaining wild population of the Rio Grande Silvery Minnow Hybognathus amarus (a federally endangered desert river fish), and provide comparisons with mesohabitat availability in the middle Rio Grande, New Mexico, from 1994 to 1996.

Methods
We collected fish monthly at two sites (separated by 160 km) near the northern and southern limits of the species' current range, and we recorded depth, velocity, substrate, and mesohabitat type for each habitat surveyed. Mesohabitat availability was recorded across 10 equally spaced and fixed transect lines at both study sites.

Result
Rio Grande Silvery Minnow most frequently occupied mesohabitats characterized by relatively shallow depths (≤25 cm) and low to near-zero water velocities (≤15 cm/s). Statistical analyses indicated that mesohabitats occupied by the species were not the most frequently available at the study sites, suggesting a preference for shallow, low-velocity habitats. Relatively high abundance of Rio Grande Silvery Minnow (n = 10,971), especially compared with post-2009 abundance, facilitated robust characterization of species-specific habitat associations.

Conclusion
Comparison of our results with other studies of pelagic broadcast-spawning leuciscids (pelagophils) endemic to the Great Plains and desert rivers of North America suggested broad overlap in mesohabitat associations among members of this reproductive guild. Our work contributes to a growing body of research aimed at conserving this declining reproductive ecotype of freshwater fishes and suggests that increasing hydraulic diversity through innovative management approaches (e.g., habitat creation, restoration of fluvial processes, and preservation of natural streamflow characteristics) will be crucial for their long-term recovery and conservation.