bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Fetal Case with Midgut Volvulus*
Authors: Suzumori Kaoru , Adachi Ritsuko , Yagami Yoshiaki , Togari Hajime 
Published: August 2010

AbstractA fetus with midgut volvulus is described. The mother had developed polyhydramnios, and the fetus was found by sonography to have dilated fluid‐filled structures compressing the chest in the upper abdomen. Percutaneous aspiration of the upper abdominal mass was performed to identify the content and know whether decompressing the chest would be beneficial. The removal of meconium‐stained fluid accomplished an improvement of the fetal biophysical profile. The infant was delivered by low transverse cesarean section, and survived with immediate removal of the fluid in the abdominal mass and ventilatory therapy.
A Comparison of Vaginal Ultrasonic‐Guided and Laparoscopic Retrieval of Oocytes for in vitro Fertilization
Authors: Kovacs G. T. , King C. , Cameron I. , Cushnahan L. , Wood E. C. , Leeton J. F. , Renou P. , Shekleton P. , Lenz S. , Baker G. 
Published: August 2010

AbstractA retrospective analysis was undertaken to compare the less invasive technique of vaginal ultrasonic‐guided oocyte retrieval with the standard laparoscopic technique. We have shown that the outcome of the transvaginal technique with respect to oocytes harvested, fertilization rate, and pregnancy rate is comparable with the laparoscopy technique. We have also shown that 9 clinicians with little previous expertise in ultrasound have been able to incorporate this technique into a busy and successful in vitro fertilization unit.
Plasma Catecholamine Metabolites and Polycystic Ovary Syndrome
Authors: Yoshino Kazuo , Takahashi Kentaro , Nishigaki Arata , Eda Yoshimi , Kitao Manabu 
Published: August 2010

AbstractIt has been postulated that catecholamine metabolism may be altered in cases of polycystic ovary syndrome. To search for possible correlations between catecholamine metabolism and hormonal disturbances, we have studied the serum LH, LH:FSH ratio, testosterone, and plasma catecholamine metabolites in patients with polycystic ovary syndrome and in control subjects with normal ovulatory cycles. The metabolites studied were 3‐methoxy‐4‐hydroxyphenylglycol (MHPG) and 3,4‐dihydroxyphenyl‐acetic acid (DOPAC) as markers of adrenergic activity and dopaminergic activity, respectively. The polycystic ovary was divided into 2 patterns [general cystic pattern (GCP) and peripheral cystic pattern (PCP}] as determined by ultrasound. The results were as follows: 1) Serum LH, LH:FSH ratios, and plasma MHPG levels in patients with polycystic ovary syndrome were significantly higher than in the controls. 2) In cases of polycystic ovary syndrome, serum LH, LH:FSH ratios, and testosterone showed no significant correlations with catecholamine metabolites. 3) Using the ultrasonographical classification, we found that plasma MHPG levels of the GCP group were significantly higher compared with the PCP group in patients with polycystic ovary syndrome. Thus, catecholamine metabolism is altered in patients with polycystic ovary syndrome, and ultrasonography revealed different patterns of catecholamine metabolism.
Chromosomal Studies on 934 Induced Abortuses of Middle‐Aged Pregnant Women
Authors: Hoshi Nobuhiko , Yamagami Yukiko , Hanatani Kaoru , Tanaka Toshinobu , Fujimoto Seiichiro 
Published: August 2010

AbstractA total of 934 induced abortuses of middle‐aged pregnant women (35–48 years old) were chromosomally surveyed. The mean gestational age was 7.6±2.0 (S.D.) weeks after the first day of the last menstrual period, and the mean maternal age was 39.6±2.7 (S.D.) years. There was a high incidence of chromosomally abnormal fetuses in induced abortions, which markedly increased with the advancing age of the women: 9.6% (40/418) for the 35–39‐year‐old age group, 20.7% (100/484) for the 40–44‐year‐old age group, and 43.8% (14/32) for the 45–48‐year‐old age group, averaging 16.5%.
Flow Cytometric DNA Analysis with Use of Normal Lymph Node Cells as an Internal Reference Standard in Ovarian Cancer
Authors: Takahashi Yoshiki , Chiba Takashi , Matsumoto Hisanori , Ishiguro Tatsuya , Yoshida Yoshinobu 
Published: August 2010

AbstractFresh frozen and paraffin‐embedded tumor specimens of 21 patients with ovarian cancer were investigated by means of flow cytometry. In 4 patients, the fresh frozen tumor specimens (fresh tumor specimens) of ovarian tumors were measured for the DNA ploidy and index. We used the paraffin‐embedded normal lymph node tissue specimens which were acquired from retroperitoneal lymphadenectomy as the internal reference standard (IS). In all 21 patients, the paraffin‐embedded tumor specimens mixed with a lymph node specimen as an IS (tumor specimen with IS) were measured. In addition, all 21 paraffin‐embedded tumor specimens without a lymph node tissue specimen (tumor specimens without IS) were measured. In 4 cases which were measured with the fresh tumor specimens, all 4 tumor specimens with IS had the same patterns of DNA ploidy as the fresh tumor specimens. Of 21 patients, 6 patients showed different DNA ploidy patterns between the tumor specimens with and without IS. Furthermore, all of these 6 patients showed diploidy in the tumor specimens without IS while showing aneuploidy in the tumor specimens with IS. Fourteen (66.7%) of 21 tumor specimens with IS were aneuploidy despite aneuploidy of only 8 (38.1%) tumor specimens without IS. All 4 patients with stage I had diploidy in the tumor specimens with IS, and 13 (81.3%) of 16 patients with stage III or IV had aneuploidy. All 8 patients with diploidy in the tumor specimens with IS had survived for 1–2 years. It is possible that the new method of the use of paraffin‐embedded normal lymph node tissue specimens as an internal reference standard accurately shows DNA aneuploidy, as well as being reliable as a predictor for the short term prognosis of patients with ovarian cancer.
Acardius Anceps: Report of 3 Cases
Authors: Ko Tsang‐Ming , Tzeng Shiang‐Jong , Hsieh Fou‐Jou , Chu Jan‐Show 
Published: August 2010

AbstractAcardius anceps is an uncommon but serious consequence of multiple pregnancy, usually in monozygotic twins. There are great variations in gross appearance and pathologic features. Recently we have encountered 3 cases of acardius anceps in 3 sets of twin pregnancy. The subcutaneous edema was so extensive and severe that no facial structures could be recognized; however, the skull bones could be detected by prenatal ultrasound examination and confirmed by postnatal radiography. The hearts were all severely malformed and many of the visceral organs were also defective. Prenatal blood gas analysis in 2 affected fetuses showed severe hypoxemia. All 3 pregnancies were terminated before the normal co‐twin reached viability. One set of the twins was delivered by hysterotomy because of the potential dystocia caused by bulky fetal mass due to severe hydropic change. Prenatal ultrasound examination is a very useful tool in the diagnosis and management of this anomaly.
A Study of Adult T‐Cell Leukemia Virus (ATLV) Infection in the Field of Obstetrics: Its Epidemiology, Vertical Transmission and Familial Clustering
Authors: Matsumoto Reiko , Inaba Noriyuki , Shimizu Hiroshi , Yamaguchi Harumi , Cho Syuwa , Takamizawa Hiroyoshi 
Published: August 2010

AbstractNine hundred and seventy‐one healthy individuals in Iwate Prefecture, 659 pregnant women in Ishigaki Island, 487 pregnant women in Chiba Prefecture and 108 familial members of the ATLA‐Ab‐positive pregnant women (pregnant carrier women) were tested for ATLA‐Ab by the PA, EIA and WB tests. 1) The rate of agreement of EIA with the PA test was 88.4% and there were no false negative sera by both examinations. These results indicate the both tests are available for mass screening. 2) In Iwate and Chiba Prefectures, the ATLA‐Ab‐positive rates of pregnant women were 5.3 and 0.6%, respectively. In addition, the incidences for healthy individuals ranged from 5.3 to 21.1% by age in Iwate Prefecture. Thus, Iwate Prefecture was found to equal Ishigaki Island (7.1%) in ATLA‐Ab detection rates. 3) Forty‐five (41.7%) out of 108 familial members of 15 pregnant carrier women were found to be seropositive for ATLA‐Ab, which confirms a certain familial clustering of ATLV.
Extracorporeal Spread and Its Prognostic Impact in Stages I and II (FIGO) Endometrial Carcinoma
Authors: Sakuragi Noriaki , Tanaka Toshinobu , Satoh Chikara , Nishiya Masashi , Ohkouchi Toshihiro , Tsumura Norihiko , Takeda Naoki , Hirahatake Koji , Sagawa Tadashi , Ohkubo Hitoshi , Fujimoto Seiichiro 
Published: August 2010

AbstractPrognostic risk factors were statistically analyzed from the histopathologic data obtained from 90 Japanese women with stages I and II endometrial carcinoma treated surgically, including systemic retroperitoneal lymph node dissection, between June 1979 and June 1989.In stage Ia endometrial carcinoma, pelvic and paraaortic nodes metastasis were seen in 13.8(4/29)% and 0.0(0/19)% of patients, respectively. In stage Ib, the incidence of pelvic and paraaortic node metastasis was 25.6(11/43)% and 9.7(3/31)%, respectively. In stage II, the incidence was 38.9(7/18)% and 13.3(2/15)%, respectively.Prognosis of patients even with deep myometrial invasion (>=2/3) or G3 tumor was fairly good (5‐year survival rate: 87.5% and 85.7%, respectively) if the disease was histologically confined to the uterine corpus. Once the tumor spread outside the corpus uteri, the survival rate of patients was strongly affected by the grade of the tumor, moderate to marked lymph‐vascular space invasion of tumor cells, or tumor invading middle or outer third of myometrium (P<0.05 for each factor). In summary, endometrial cancer frequently metastasize to pelvic and paraaortic lymph nodes even in the early stages, and lymph node metastasis and other extracorporeal spread of disease have a serious impact on patient survival. Prognosis of patients with extra‐corporeal spread of disease seems to be determined by the high grade of tumor and lymph‐vascular space invasion. These results suggest that surgical exploration including paraaortic lymph node dissection to accurately evaluate the extent of the disease is essential to estimate the patient's prognostic risk and to individualize the treatment schedule.
Epidural Anesthesia Shortens Duration of Labor in Singleton Vertex Presentation Spontaneous Delivery
Authors: Lurie Samuel , Matzkel Avi 
Published: August 2010

AbstractInfluence of epidural anesthesia on the duration of labor was studied in 1,206 parturients having spontaneous singleton vaginal delivery. In primiparous women, the mean first stage was 3.52 hr in the epidural group, and 7.68 hr in the control group (p<0.001), the mean second stage was 25.78 min in the epidural group, and 43.58 min in the control group (p<0.001). In the multiparous women, the mean first stage was 2.06 hr in the epidural group, and 3.85 hr in the control group (p<0.001), the mean second stage was 17.06 min in the epidural group, and 25.42 min in the control group (p<0.0001). The conclusion is that epidural anesthesia shortens the duration of first and second stages of labor in singleton vaginal delivery.
Asymptomatic Axial Torsion of the Pregnant Uterus: A Cause of the Failure of Induction of Mid‐Trimester Abortion
Authors: Gupta Indu , Handa Pusnap R. , Khera Kamla R. , Mahajan Urmil 
Published: August 2010

AbstractTorsion of gravid uterus is a rare obstetric condition in which diagnosis is usually made only on laparotomy. A case of asymptomatic axial torsion of uterus during mid‐trimester, because of an ovarian cyst is reported. This presented as a failure of induction of abortion by extra‐amniotic isotonic saline instillation and oxytocin infusion.
Treatment Effects of GnRH Agonist on the Binding of Estrogen and Progesterone, and the Histological Findings of Uterine Leiomyomas
Authors: Uemura Tsuguo , Mori Jun , Yoshimura Yasuhiro , Minaguchi Hiroshi 
Published: August 2010

AbstractThe changes in the histology and steroid hormone binding capacity of the uterine leiomyomas treated with; GnRH agonists (GnRHa buserelin acetate in, 900 μg/day for 16 weeks) were investigated.The occurrence of hyaline degeneration in the myometrium was significantly higher in the GnRHa‐treated group than in the control group, and the grade of hyaline degeneration was more advanced in the GnRHa group. After the GnRHa treatment, the Bmax of the estrogen receptor increased significantly in the leiomyomas and myometrium. The Bmax of progesterone receptors in the myometrium decreased significantly and the reduction rates of leiomyomas (% of the initial volumes) measured by MRI correlated (r=0.775) with the Bmax of progesterone receptors.In summary, GnRHa caused hyaline degeneration of the uterine leiomyomas which were responsible for the shrinkage. The shrunk leiomyomas have the potential for regrowth in response to estrogen as they still have high concentrations of the estrogen receptors.
Changes in Bone Mineral Density and Fracture Prevalence in Japanese Women after Oophorectomy
Authors: Seimiya Yumiko , Chen Jui‐Tung , Hirai Yasuo , Hasumi Katsuhiko , Masubuchi Kazumasa , Shiraki Masataka , Matsuura Masanori , Aoki Choju 
Published: August 2010

AbstractThe bone changes after gynecological surgery during the early phase of recovery were examined. The subjects were randomly selected from women who had undergone bilateral oopho‐hysterectomies (OOX, n=98, 46.0±5.0 year‐old) or hysterectomies (HX, n=75, 43.6±4.6 year‐old) within 4 years prior to entering the study. The ovarian functions in the HX group were presumed to be intact following the hysterectomies, judging from the cytological evaluation of the vaginal pap smears.The bone morphological changes in both groups were examined to measure the cortical thickness of the metacarpal bone (MCI) on hands X‐ray film using microden‐sitometry, and the posterior/anterior height ratios (P/A ratio) of the entire vertebral bodies, on vertebral X‐ray films using a digitizer. The changes in bone mineral densities in both groups were measured by dual energy X‐ray absorptiometry at lumbar vertebrae (L2–4 BMD) and by microdensitometry at the metacarpal cortical bone; the bone densities of metacarpal bone were referenced by the density of aluminum step wedge on the same X‐ray films. The prevalence of vertebral body fractures (P/A ratio>1.4) in the OOX group (5.1%) was 3.9 times higher than that in the HX group (1.3%). There was a significant decrease in MCI in the OOX group compared with the HX group (p<0.01). L2–4 BMD in the OOX and HX group were 1.07±0.15 and 1.16±0.13 g/cm2, respectively (p<0.001). The bone densities of the metacarpal cortical bone in the OOX and HX group were 2.57±0.38 and 2.81±0.38 with an aluminum density equivalent, respectively (p<0.001).When the bone mineral density of the operated women exhibited below ‐1SD of age‐matched Japanese reference value, their bone mineral densities were defined as low. The relative risk (Odd's ratios) of low bone mineral density at the lumber vertebrae and metacarpal cortical bone against the HX group was 4.6 and 6.9 (p<0.05), respectively. The Odd's ratio of lower MCI between OOX and HX group was 4.0 (p<0.05).The bone changes in either density or morphology were apparent shortly after oophorectomy. Oophorectomy is thus considered a significant risk for the development of osteoporosis.
Experience with Screening for Abnormal Glucose Tolerance in Pregnancy: Maternal and Perinatal Outcome
Authors: Rizvi Javaid H. , Saadia Rasul , Shamim Malik , Amin Rehamatuallh , Ata Khan M. 
Published: August 2010

AbstractIn order to determine the prevalence of glucose intolerance in pregnancy, 2,230 consecutive women attending the antenatal clinic at the Aga Khan University Medical Centre in Karachi, Pakistan were subjected on the first antenatal visit, irrespective of gestational age, to a 75 g glucose challenge followed 2 hr later by plasma glucose determination. The test, was repeated at 28–32 weeks of gestation for those patients who had an abnormal initial screen at <28 weeks gestation followed by a normal glucose tolerance test and for those who had a risk factor for gestational diabetes even though the initial screen at <28 weeks gestation was normal. The initial glucose challenge test was abnormal (2 hr plasma glucose >140 mg%) in 8.6% of the screened population. An oral glucose tolerance test on these patients revealed a prevalence for the entire population of 3.5% of gestational diabetes and 1.9% of impaired glucose tolerance test based on the modified O'Sullivan criteria. Patients with abnormal glucose tolerance test were older, had higher parity, a past history of macrosomia and a family history of diabetes compared to the controls. These patients also had a higher incidence of preterm labour and caesarean section. In the neonates hypoglycemia and hy‐perbilirubinemia were similarly higher. The fetal abnormality rate was 5.6% and the perinatal mortality was 28/1,000 which were higher than the controls.
Sheehan's Syndrome Following Eclampsia: A Case Report
Authors: Uhiara Joseph E. , Narayan Raghwa , Kumar S. 
Published: August 2010

AbstractA case of Sheehan's syndrome following eclampsia is presented. The clinical features were not recognised early probably because the condition was not suspected, being a rare sequel of eclampsia. Non availability of specialist care may have been partly responsible and is highlighted. Increased awareness of all possible aetiological factors in this condition is necessary for clinicians.
Ultrasonography and Doppler Studies in Twin‐to‐Twin Transfusion Syndrome
Authors: Ishimatsu Junji , Yoshimura Osamu , Manabe Akihiko , Matsuzaki Touru , Tanabe Ryouhei , Hamada Teiji 
Published: August 2010

AbstractIn 40 twin pregnancies, the evaluation of hemodynamics by ultrasound was performed during the period January 1986 through September 1991. The blood flow velocities' waveforms in the umbilical artery, umbilical vein and tricuspid valve, and the total cardiac dimension, were obtained by ultrasonography in conjunction with 3.5 MHz pulsed Doppler ultrasound. Six patients with twin pregnancies were identified as having twin‐to‐twin transfusion syndrome (TTS), on the basis of like‐sex twins with monochorionic diamniotic placentation, vascular anastomosis in the placenta, and umbilical cord venous blood hemoglobin difference exceeding 5 g/dl at delivery. No distinctive findings for TTS were revealed by the measurement of umbilical artery blood flow velocity waveforms. However, cardiomegaly in 5 recipient fetuses and tricuspid regurgitation and biphasic umbilical vein waveforms in 3 recipient fetuses constituted characteristic features of TTS. Ultrasonography and a Doppler study might be beneficial in diagnosing TTS and evaluating the hemodynamics in a recipient fetus.
Predictive Value of 1 Hour 50g Oral Glucose Load Screening Test for Gestational Diabetes Mellitus Compared to 3 Hour Oral Glucose Tolerance Test in High Risk Pregnant Women
Authors: Jirapinyo Mayuree , Puavilai Gobchai , Chanprasertyotin Suwannee , Tangtrakul Somsak 
Published: August 2010

AbstractA prospective study for detecting gestational diabetes mellitus was undertaken to evaluate the use of one hour plasma glucose level after 50 g glucose loading test (1‐hr GLT) as compared to the traditional 3‐hours 100 g oral glucose tolerance test (3‐hr OGTT) in 396 high risk cases. Each patient, had 1‐hr GLT and 3‐hr OGTT performed in a separate week. Forty‐two cases (10.6%) who had abnormal 3‐hr OGTT were classified as gestational diabetes (GDM). One hundred and sixty cases (40.4%) had an abnormal 1‐hr GLT (plasma glucose level ≥140 mg/dl). Thirty‐six of these 160 cases (22.5%) had an abnormal 3‐hr OGTT. In 236 women (59.6%) that had normal 1‐hr GLT (plasma glucose level <140 mg/dl) only 6 cases (2.5%) had an abnormal 3‐hr OGTT. If 1‐hr plasma glucose level ≥150 mg/dl was used as the cutoff point, 110 cases (27.8%) were found to have abnormal 1‐hr GLT, and 35 of these 110 cases (31.8%) had an abnormal 3‐hr OGTT. Seven of 286 women (2.4%) that had normal 1‐hr GLT (plasma glucose level <150 mg/dl) had an abnormal 3‐hr OGTT. The sensitivity and specificity of the 1‐hr GLT when abnormal 3‐hr OGTT was used as gold standard for detecting GDM were 85.7% and 65% respectively (BS ≥140 mg/dl). Whereas the sensitivity and specificity were 83.3% and 78.8% respectively when plasma glucose level >150 mg/dl was used as the cut point. From this study in oriental pregnant women it can be concluded that 1‐hr GLT is a valuable screening test for GDM.
Clinical Observation of Personality Characteristics of Perimenopausal Women with Undefined Complaints
Authors: Ushiroyama Takahisa , Sugimoto Osamu 
Published: August 2010

AbstractPersonality tests, including the Self‐Rating Questionnaire for Depression (SRQ‐D), the Minnesota Multiphasic Personality Inventory Alexithymia Scale (MMPI‐AS), and the Egogram Check List (ECL) were completed by 202 perimenopausal women with undefined complaints. Patients diagnosed as having mental disorders showed SRQ‐D scores of over 16 points. Patients diagnosed as having mental disorders showed MMPI‐AS scores of over 13 points, which can be estimated as alexithymia. Patients experiencing climacteric disorders and the ovarian deficiency syndrome showed slightly higher MMPI‐AS scores than healthy middle‐aged women. The average ECL scores of patients diagnosed as having mental disorders tended to show an N‐shape pattern. The findings suggest that personality tests would be helpful for screening perimenopausal women with mental disorders who are seen at outpatient gynecology clinics.
Is Postoperative Radiotherapy Beneficial in the Management of Stage I‐II Squamous‐Cell Carcinoma of the Uterine Cervix with Negative Metastatic Nodes and Positive Parametrial Involvement?: A Retrospective Review of 70 Patients
Authors: Takamura Akio , Mizoe Jun‐etsu , Arimoto Takuro , Kamada Tadashi , Shirato Hiroki , Matsuoka Yoshisuke , Tomita Masayoshi , Irie Goro 
Published: August 2010

AbstractSeventy patients having squamous‐cell carcinoma of the uterine cervix FIGO Stage I‐II with negative lymph nodes and positive parametrial involvement received postoperative radiotherapy following radical hysterectomy and pelvic lymphadenectomy. In 48 patients with microscopic parametrial invasion, the 5‐year survival rate was 92%. The other 22 patients with macroscopic parametrial involvement had a 5‐year survival rate of 75%. The overall recurrence rate was 13% (9 of 70). The sites of failure were 3 pelvic alone, 5 distant metastases alone, and 1 combined pelvis and para‐aortic lymph node. All of those with recurrence were Stage‐II cases. The absolute pelvic‐control rate was 94.3% (66/70). Fifty‐six percent of the patients experienced mild‐to‐moderate lymphedema. Severe complications requiring surgical intervention were observed in 6 patients (5 bowel obstructions and 1 femoral head fracture). A review of the literature suggests that early carcinoma can be successfully treated by surgery alone. Taking into consideration the risk and benefits involved, postoperative radiotherapy is not recommended for most cases with cervical carcinoma with negative lymph nodes and positive parametrial involvement in the present form, despite excellent local control. However, no definite conclusion can be drawn from this retrospective analysis.