bluuebunny/crossref_metadata_2025_split huggingface dataset:
La participation en science à l’ère des enjeux globaux
Authors: Schiele Bernard 
Published: November 2011

Résumé Pour penser la participation dans le monde globalisé d’aujourd’hui quatre dimensions au moins doivent être prises en compte : la conscience de l’environnement, l’impact des techno-sciences sur la société, la poussée de la communication, et l’impératif économique. Planétaires, elles sont partout à l’œuvre. Chacune importe moins que l’ensemble de leurs interactions croisées. Elles ont entraîné une transformation des modes de production du savoir, de sa mise en circulation, de son appropriation, et des modalités de sa mobilisation. Cette évolution se traduit par une ambivalence du public par rapport aux sciences. Ce qui oblige à une reconsidération de la conception de la participation des acteurs sociaux dans les situations où différents rapports au savoir sont mobilisés afin de tenir compte des différents expériences, perspectives et intérêts des groupes impliqués.
Nicolas Sarkozy : des vœux en continuité pour le candidat de la rupture
Authors: Finniss-Boursin Françoise 
Published: November 2011

Résumé À l’heure où l’évidence des changements qui affectent le champ de la communication politique (l’exhibition de certains moments de la vie privée, la médiatisation de l’individu sous les habits institutionnels) pourrait inciter à laisser pour compte les persistances, Françoise Finniss-Boursin, qui a analysé tous les discours de vœux des Présidents français depuis 1958, s’intéresse aux vœux télévisés du Président Nicolas Sarkozy (2007-2009). Comment l’autoproclamé candidat de la « rupture » allait-il aborder cet exercice ? Au-delà de l’éclairage sur le décalage entre promesses et mises en pratique de l’actuel président, Françoise Finniss-Boursin engage une réflexion sur le rôle du rite et de la solennité dans la construction d’un représentant politique. Ce n’est pas parce que la politique est l’affaire de tous et que le politique se dissémine aujourd’hui partout que ne persistent pas des lieux où se construit la figure politique.
Influence of discipline of provider and model of care on an arthritis educational intervention in primary care
Authors: Lineker Sydney C. , Husted Janice A. , Brown K. Stephen 
Published: November 2011

AbstractObjectiveTo identify both provider and organizational characteristics that predicted outcomes following an educational intervention (9‐hour workshop and followup reinforcement activities) developed to improve the management of arthritis in primary care.MethodsProviders completed a survey at baseline and at 6 months postworkshop, including a case scenario for early rheumatoid arthritis. Providers were asked how they would manage the case and their responses were coded to calculate a best practice score, ranging from 0–7. Two‐level hierarchical linear modeling was used to determine which of the measured provider and organizational factors predicted best practice scores at followup.ResultsA total of 275 multidisciplinary providers from 131 organizations completed both baseline and followup surveys. Best practice scores increased by 17% (P < 0.01); however, the mean score at 6‐month followup remained relatively low (2.68). Significant predictors of best practice scores at followup were discipline of provider and model of primary care in which they worked (P < 0.05), adjusting for baseline practice scores and clustering of providers within organizations. Physicians, nurse practitioners, and rehabilitation therapists scored higher than nurses, students, and other health care providers (P < 0.01). Physician networks scored significantly lower than providers from multidisciplinary‐oriented models of care (P = 0.02).ConclusionThese results have implications for the education of health professionals and the design of models of care to enhance arthritis care delivery.
Consensus treatments for moderate juvenile dermatomyositis: Beyond the first two months. Results of the Second Childhood Arthritis and Rheumatology Research Alliance Consensus Conference
Authors: Huber Adam M. , Robinson Angela B. , Reed Ann M. , Abramson Leslie , Bout‐Tabaku Sharon , Carrasco Ruy , Curran Megan , Feldman Brian M. , Gewanter Harry , Griffin Thomas , Haines Kathleen , Hoeltzel Mark F. , Isgro Josephine , Kahn Philip , Lang Bianca , Lawler Patti , Shaham Bracha , Schmeling Heinrike , Scuccimarri Rosie , Shishov Michael , Stringer Elizabeth , Wohrley Julie , Ilowite Norman T. , Wallace Carol ,   Juvenile Dermatomyositis Subcommittee of the Childhood Arthritis and Rheumatology Research Alliance
Published: November 2011

AbstractObjectiveTo use consensus methods and the considerable expertise contained within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) organization to extend the 3 previously developed treatment plans for moderate juvenile dermatomyositis (DM) to span the full course of treatment.MethodsA consensus meeting was held in Chicago on April 23–24, 2010, involving 30 pediatric rheumatologists and 4 lay participants. Nominal group technique was used to achieve consensus on treatment plans that represented typical management of moderate juvenile DM. A preconference survey of CARRA, completed by 151 (56%) of 272 members, was used to provide additional guidance to the discussion.ResultsConsensus was reached on timing and rate of steroid tapering, duration of steroid therapy, and actions to be taken if patients were unchanged, worsening, or experiencing medication side effects or disease complications. Of particular importance, a single consensus steroid taper was developed.ConclusionWe were able to develop consensus treatment plans that describe therapy for moderate juvenile DM throughout the treatment course. These treatment plans can now be used clinically, and data collected prospectively regarding treatment effectiveness and toxicity. This will allow comparison of these treatment plans and facilitate the development of evidence‐based treatment recommendations for moderate juvenile DM.
Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3
Authors: Honjo Hiroaki , Uwai Yuichi , Aoki Youhei , Iwamoto Kikuo 
Published: November 2011

ABSTRACTNonsteroidal anti‐inflammatory drugs (NSAIDs) delay the renal excretion of antifolate methotrexate by inhibiting human organic anion transporters hOAT1 (SLC22A6) and hOAT3 (SLC22A8). In this study, uptake experiments were performed using Xenopus laevis oocytes to assess stereoselectivity in the inhibitory characteristics of flurbiprofen, ibuprofen and naproxen against hOAT1 and hOAT3. Uptake of p‐aminohippurate by hOAT1 was inhibited by each enantiomer of the three NSAIDs, and the inhibitory effect was superior in each (S)‐enantiomer around 10 µ m. The apparent 50% inhibitory concentrations were estimated to be 0.615 µ m for (S)‐flurbiprofen, 2.84 µ m for (S)‐ibuprofen and 1.93 µ m for (S)‐naproxen, and these values were significantly lower than those of the respective (R)‐enantiomers [(R)‐flurbiprofen: 2.35 µ m, (R)‐ibuprofen: 6.14 µ m, (R)‐naproxen: 5.26 µ m]. Furthermore, the (S)‐NSAIDs at 3 µ m reduced methotrexate accumulation in hOAT1‐expressing oocytes more strongly than the corresponding (R)‐enantiomers. All enantiomers inhibited hOAT3‐mediated transport of estrone sulfate and methotrexate, but there was no difference between both enantiomers of each NSAID in the inhibitory potencies. Eadie‐Hofstee plot analysis showed that (S)‐flurbiprofen and (R)‐flurbiprofen inhibited hOAT1 and hOAT3 in a competitive manner. These findings represent the stereoselective inhibitory potencies of flurbiprofen, ibuprofen and naproxen on hOAT1, and the (S)‐enantiomers are greater. In contrast, stereoselectivity was not recognized in their inhibitory effect on hOAT3. Copyright © 2011 John Wiley & Sons, Ltd.
ChemInform Abstract: RE8Rh17Sb14 (RE: La, Ce, Pr, Nd) with a CaBe2Ge2‐Related Superstructure Through Rhodium—Antimony‐Ordering and Vacancy Formation.
Authors: Schellenberg Inga , Hoffmann Rolf‐Dieter , Schwickert Christian , Poettgen Rainer 
Published: November 2011

AbstractThe title compounds are synthesized by arc melting of the elements and characterized by powder XRD and magnetic measurements.
ChemInform Abstract: Novel Environment‐Friendly Yellow Pigments Based on (Bi, La)VO4.
Authors: Wendusu Wendusu , Ikawa Ken‐ichi , Masui Toshiyuki , Imanaka Nobuhito 
Published: November 2011

AbstractBi1‐xLaxVO4 (0 ≤ x ≤ 0.15) pigments are hydrothermally synthesized from an aqueous solution of Bi(NO3)3, La(NO3)3, NH4VO3, HNO3, and NH3 (autoclave, pH 6, 443—503 K, 72 h).
ChemInform Abstract: Real Structure and Diffuse Scattering of Sr0.5Ba0.5Si2O2N2 :Eu2+ — A Highly Efficient Yellow Phosphor for pc‐LEDs.
Authors: Seibald Markus , Oeckler Oliver , Celinski Vinicius R. , Schmidt Peter J. , Tuecks Andreas , Schnick Wolfgang 
Published: November 2011

AbstractThe title phosphor (2 mol% Eu) is synthesized from a stoichiometric mixture of (Sr0.5Ba0.5)2SiO4:Eu and α‐Si4N4 in 5% H2/N2 (1450 °C, 5 h) and characterized by powder XRD, SAED, and luminescence spectroscopy.
ChemInform Abstract: Ba2.2Ca0.8Mg4F14, a New “Solid Solution Stabilized” Matrix for an Intense Blue Phosphor.
Authors: Kubel F. , Pantazi M. , Hagemann H. 
Published: November 2011

AbstractThe title compound is prepared from precursors obtained by precipitation from aqueous solutions of Ba(OH)2, Ca(OAc)2, and Mg(OAc)2 with NH4F (Pt crucible, 850 °C, 3 h, yield given in g).
ChemInform Abstract: Crystal Structure and Magnetism of the Fe6Ga6‐xSi1+x (where x = 0.05) Compound.
Authors: Lyutyy P. Ya. , Svitlyk V. O. , Fedorchuk A. O. 
Published: November 2011

AbstractFe6Ga5.95Si1.05 is prepared from the elements by arc‐melting and characterized by powder XRD, magnetic measurements, and spin polarized LDA + U electronic structure calculations.
ChemInform Abstract: {Os5Lu20}I24, the First Extended Cluster Complex of Lutetium with Eight‐Coordinate Endohedral Osmium Atoms in Two Different Environments.
Authors: Bruehmann Matthias , Mudring Anja‐Verena , Valldor Martin , Meyer Gerd 
Published: November 2011

AbstractThe title compound is prepared by a conproportionation reaction of Lu metal and LuI3 in the presence of Os (Os/Lu/LuI3 = 2:4:5; 1200 °C, sealed Ta‐tube, 3 d; annealing at 850 °C, 13 d).
ChemInform Abstract: Heterogeneous Continuous Flow Synthetic System Using Cyclohexane‐Based Multiphase Electrolyte Solutions.
Authors: Okada Yohei , Yoshioka Tomohiko , Koike Mikio , Chiba Kazuhiro 
Published: November 2011

AbstractThe method is applied to electrochemically induced transformations including electron‐transfer induced [2 + 2] cycloaddition reactions.
ChemInform Abstract: Rh‐Catalyzed Asymmetric 1,4‐Addition of Arylboronic Acids to α,β‐Unsaturated Ketones with Difluorphos and Synphos Analogues.
Authors: Berhal Farouk , Wu Zi , Genet Jean‐Pierre , Ayad Tahar , Ratovelomanana‐Vidal Virginie 
Published: November 2011

AbstractIt is found that Difluorphos (II) and the Synphos analogues (I) efficiently promote the asymmetric 1,4‐addition of arylboronic acids to various α,β‐unsaturated ketones.
ChemInform Abstract: Catalytic Enantioselective Protonation of Enol Trifluoroacetates by Means of Hydrogenocarbonates and Cinchona Alkaloids.
Authors: Claraz Aurelie , Leroy Jerome , Oudeyer Sylvain , Levacher Vincent 
Published: November 2011

AbstractCyclic enol trifluoroacetates undergo efficient asymmetric protonation yielding the corresponding ketones in up to 93% e.e.
ChemInform Abstract: Pyrrolidinyl‐Sulfamide Derivatives as a New Class of Bifunctional Organocatalysts for Direct Asymmetric Michael Addition of Cyclohexanone to Nitroalkenes.
Authors: Chen Jia‐Rong , Fu Liang , Zou You‐Quan , Chang Ning‐Jie , Rong Jian , Xiao Wen‐Jing 
Published: November 2011

AbstractAsymmetric Michael addition of nitrostyrenes (II) and nitrodiene (IV) towards cyclohexanone is efficiently catalyzed by a novel bifunctional pyrrolidine—sulfamide organocatalyst.
ChemInform Abstract: Catalytic Asymmetric C—H Insertions of Rhodium(II) Azavinyl Carbenes.
Authors: Chuprakov Stepan , Malik Jamal A. , Zibinsky Mikhail , Fokin Valery V. 
Published: November 2011

AbstractIn the presence of chiral Rh(II)‐carboxylates, 1‐sulfonyl‐1,2,3‐triazoles are converted into azavinyl carbenes which are inserted into unactivated cycloalkanes or alkanes to give β‐chiral sulfonamides.
ChemInform Abstract: Asymmetric Henry Reaction of Aldehydes Catalyzed by a Recyclable MCM‐41 Supported Copper(II) Salen Complex.
Authors: Dhahagani Karuthamohamed , Rajesh Jegathalaprathaban , Kannan Ramanujam , Rajagopal Gurusamy 
Published: November 2011

AbstractA silica‐supported Cu(II)—salen complex is successfully applied as catalyst in the asymmetric Henry reaction of aromatic (I) and aliphatic aldehydes (IV) with nitromethane.
ChemInform Abstract: A Novel Trifunctional Organocatalyst for the Asymmetric Aldol Reaction: A Facile Enantioselective Synthesis of β‐Hydroxyketones.
Authors: Reddy B. V. Subba , Bhavani K. , Raju A. , Yadav J. S. 
Published: November 2011

AbstractA wide range of aromatic aldehydes smoothly undergo asymmetric aldol reaction towards acetone in the presence of a novel prolinamide‐derived organocatalyst (QACP) to give hydroxyketones (III) in moderate to good enantioselectivities (up to 92% e.e.).
ChemInform Abstract: Enantioselective Friedel—Crafts Alkylations Catalyzed by Well‐Defined Iridium and Rhodium Half‐Sandwich Complexes.
Authors: Carmona Daniel , Lamata Maria Pilar , Sanchez Antonio , Viguri Fernando , Oro Luis A. 
Published: November 2011

AbstractCationic Rh or Ir—bisphosphine complexes catalyze the Friedel—Crafts alkylation of various electron‐rich arenes as well as indole derivatives with trans‐crotonaldehyde (II), methacrolein (IV) or β‐nitrostyrenes (IX).
ChemInform Abstract: Solvent‐Free Synthesis of δ‐Carbolines/Carbazoles from 3‐Nitro‐2‐phenylpyridines/2‐Nitrobiphenyl Derivatives Using DPPE as a Reducing Agent.
Authors: Peng Haixia , Chen Xuxing , Chen Yanhong , He Qian , Xie Yuyuan , Yang Chunhao 
Published: November 2011

AbstractVarious functional groups are tolerated at the 2‐phenyl ring of starting nitro compounds including electron‐withdrawing substituents.
ChemInform Abstract: In‐Water Dehydrative Alkylation of Ammonia and Amines with Alcohols by a Polymeric Bimetallic Catalyst.
Authors: Ohta Hidetoshi , Yuyama Yoshinari , Uozumi Yasuhiro , Yamada Yoichi M. A. 
Published: November 2011

AbstractThe polymeric catalyst, prepared from a poly(catechol borate) and an Ir‐C5Me5 complex, is effective in the reaction of various primary and secondary amines with alcohols.
ChemInform Abstract: Rh(I)‐Catalyzed Formal [6 + 2] Cycloaddition of 4‐Allenals with Alkynes or Alkenes in a Tether.
Authors: Oonishi Yoshihiro , Hosotani Akihito , Sato Yoshihiro 
Published: November 2011

AbstractThe title reaction is catalyzed by [Rh(IMes)(cod)]ClO4, generated in situ, and affords cyclopenta‐ and cyclohexa‐fused cyclooctanones.
ChemInform Abstract: Selective ortho‐Bromination of Substituted Benzaldoximes Using Pd‐Catalyzed C—H Activation: Application to the Synthesis of Substituted 2‐Bromobenzaldehydes.
Authors: Dubost Emmanuelle , Fossey Christine , Cailly Thomas , Rault Sylvain , Fabis Frederic 
Published: November 2011

AbstractThe aldehyde substrates are protected with hydroxylamine and subjected to optimal bromination reactions.
ChemInform Abstract: Isosteviol‐amino Acid Conjugates as Highly Efficient Organocatalysts for the Asymmetric One‐Pot Three‐Component Mannich Reactions.
Authors: An Yajie , Qin Qian , Wang Chuanchuan , Tao Jingchao 
Published: November 2011

AbstractThe respective catalysts (I) and (II) are prepared from isosteviol in a three‐step synthesis.
ChemInform Abstract: Formation of Carbon—Sulfur and Carbon—Selenium Bonds by Palladium‐Catalyzed Decarboxylative Cross‐Couplings of Hindered 2,6‐Dialkoxybenzoic Acids.
Authors: Becht Jean‐Michel , Le Drian Claude 
Published: November 2011

AbstractAg2CO3/Pd(OCOCF3)2‐mediated treatment of 2,6‐dialkoxybenzoic acids with diaryl disulfides and diselenides allows simple and efficient access to diaryl sulfides and diaryl selenides.
ChemInform Abstract: A Practical Method to Stereospecifically Synthesize trans‐Stilbene Derivatives.
Authors: Jian Yujuan , Sun Gaojun , Li Jiaming , Su Dan , Li Chuanrun , Zhong Guochen 
Published: November 2011

AbstractThe title reaction is also used for the preparation of important intermediates (VI) in the synthesis of piceatannol, pinosilvine and resveratrol.
ChemInform Abstract: Oxime Palladacycle‐Catalyzed Suzuki—Miyaura Alkenylation of Aryl, Heteroaryl, Benzyl, and Allyl Chlorides under Microwave Irradiation Conditions.
Authors: Civicos Jose F. , Alonso Diego A. , Najera Carmen 
Published: November 2011

AbstractThe reaction applies a catalyst, generated in situ from (I) and tBu3P·HBF4 and Bu4NOH as a co‐catalyst and is general for various alkenyl boronic acids, potassium trifluoroborates or pinacol boronic esters and aromatic, heteroaromatic, allylic and benzylic chlorides.
ChemInform Abstract: Efficient Intramolecular Hydroarylation Catalyzed by BiIII Triflate.
Authors: Cacciuttolo Bastien , Poulain‐Martini Sophie , Dunach Elisabet 
Published: November 2011

AbstractThe bismuth agent is an efficient and environmentally friendly catalyst for intramolecular coupling of non‐activated and highly substituted olefins with non‐activated arenes.
ChemInform Abstract: Palladium‐Catalyzed Three‐Component Tandem Cyclization Reaction of 2‐(2,3‐Allenyl)acylacetates, Organic Halides, and Amines: An Effective Protocol for the Synthesis of 4,5‐Dihydro‐1H‐pyrrole Derivatives.
Authors: Cheng Jiajia , Jiang Xuefeng , Zhu Can , Ma Shengming 
Published: November 2011

AbstractThe reaction tolerates a wide range of aromatic and aliphatic amines and aromatic and alkenic iodides to afford the target pyrrole derivatives.
ChemInform Abstract: An Efficient Synthesis of Highly Functionalized Chiral Lactams.
Authors: Ornelas Martha A. , Gonzalez Javier , Sach Neal W. , Richardson Paul F. , Bunker Kevin D. , Linton Angelica , Kephart Susan E. , Pairish Mason , Guo Chuangxing 
Published: November 2011

AbstractThe SNAr‐reaction of N‐benzylpantolactam (I) with various halides is shown to proceed with no or low amounts of racemization and can be used in library synthesis.
ChemInform Abstract: Porpholactams and Chlorolactams: Replacement of a β,β′‐Double Bond in meso‐Tetraphenyl‐porphyrin and ‐chlorin by a Lactam Moiety.
Authors: Akhigbe Joshua , Haskoor John , Zeller Matthias , Brueckner Christian 
Published: November 2011

AbstractReaction of title compound (I) with hydrazine converts the lactone moiety to an N‐aminolactam (III).
ChemInform Abstract: The Benzyne Fischer‐Indole Reaction.
Authors: McAusland Donald , Seo Sangwon , Pintori Didier G. , Finlayson Jonathan , Greaney Michael F. 
Published: November 2011

AbstractThe one‐pot procedure applies an initial N‐arylation of various tosylhydrazones with aryne precursors followed by Lewis acid mediated Fischer cyclization.
ChemInform Abstract: Three‐Component Coupling Using Arynes and DMF: Straightforward Access to Coumarins via ortho‐Quinone Methides.
Authors: Yoshida Hiroto , Ito Yu , Ohshita Joji 
Published: November 2011

Abstractortho‐Quinone methides, arising from a formal [2 + 2] cycloaddition between arynes and dimethylformamide are found to undergo a [4 + 2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins such as (IV), (VI), (VIII) and (X).
ChemInform Abstract: Highly Enantioselective Hydrogenation of Quinolines Using Phosphine‐Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism, and Origin of Enantioselectivity.
Authors: Wang Tianli , Zhuo Lian‐Gang , Li Zhiwei , Chen Fei , Ding Ziyuan , He Yanmei , Fan Qing‐Hua , Xiang Junfeng , Yu Zhi‐Xiang , Chan Albert S. C. 
Published: November 2011

AbstractChiral cationic η6‐arene Ru(II) complexes are applied to a wide range of quinolines including 2‐alkyl, 2‐aryl, and 2,3‐disubstituted derivatives.
ChemInform Abstract: Synthesis of 8‐Arylquinolines via One‐Pot Pd‐Catalyzed Borylation of Quinoline‐8‐yl Halides and Subsequent Suzuki—Miyaura Coupling.
Authors: Zhang Yongda , Gao Joe , Li Wenjie , Lee Heewon , Lu Bruce Z. , Senanayake Chris H. 
Published: November 2011

AbstractThe method provides a general and efficient approach to biologically important 8‐arylquinolines.
ChemInform Abstract: FeCl3‐Mediated Synthesis of Polysubstituted Tetrahydroquinolines via Domino Mannich/Friedel—Crafts Reactions of Aldehydes and Amines.
Authors: Yang Yan‐Fang , Shu Xing‐Zhong , Wei Hai‐Long , Luo Jian‐Yi , Ali Shaukat , Liu Xue‐Yuan , Liang Yong‐Min 
Published: November 2011

AbstractDomino Mannich—intramolecular Friedel—Crafts alkylation—intermolecular Friedel—Crafts alkylation reaction of aliphatic aldehydes with aromatic amines is smoothly catalyzed by FeCl3 to give polysubstituted tetrahydroquinolines in moderate yields and moderate to good diastereoselectivities.
ChemInform Abstract: Nickel‐Catalyzed [2 + 2 + 2] Cycloaddition of Diynes and Cyanamides.
Authors: Stolley Ryan M. , Maczka Michael T. , Louie Janis 
Published: November 2011

AbstractThe process affords 2‐aminopyridine structures and is effective for reactions of internal as well as terminal diynes with a variety of cyanamides.
ChemInform Abstract: Oxidative Cycloaddition of 1,1,3,3‐Tetramethyldisiloxane to Alkynes Catalyzed by Supported Gold Nanoparticles.
Authors: Lykakis Ioannis N. , Psyllaki Androniki , Stratakis Manolis 
Published: November 2011

AbstractThe title reaction of terminal or internal alkynes catalyzed by gold nanoparticles supported on TiO2 affords oxadisiloles.
ChemInform Abstract: Aryl Diazonium Salts: A New Class of Coupling Agents for Bonding Polymers, Biomacromolecules and Nanoparticles to Surfaces
Authors: Mahouche‐Chergui Samia , Gam‐Derouich Sarra , Mangeney Claire , Chehimi Mohamed M. 
Published: November 2011

AbstractReview: ca. 150 refs.
ChemInform Abstract: Towards Cleaner Combustion Engines Through Groundbreaking Detailed Chemical Kinetic Models
Authors: Battin‐Leclerc Frederique , Blurock Edward , Bounaceur Roda , Fournet Rene , Glaude Pierre‐Alexandre , Herbinet Olivier , Sirjean Baptiste , Warth V. 
Published: November 2011

AbstractReview: 212 refs.
Artificial neural network in diagnosis of metastatic carcinoma in effusion cytology
Authors: Barwad Adarsh , Dey Pranab , Susheilia Shaily 
Published: November 2011

AbstractAims and objectives:To build an artificial neural network (ANN) model for the detection of carcinoma in effusion cytology.Materials and methods:We selected a total of 114 effusion cytology cases consisting of 57 each benign and malignant case. In all these cases, detailed cytological features, image morphometric data, densitometric data, and chromatin textural data were collected. Based on these data, we made a back propagation ANN model for diagnosing malignancy in effusion cytology. This network was designed as 25‐2‐1 (input nodes‐hidden nodes‐output node). Online back propagation method was applied for training the network. The training of the network was continued until the network error was reduced to 0.000654. Simultaneously, we also performed logistic regression (LR) analysis test to compare with ANN model performance.Result:ANN model worked excellent after adequate training. With the help of this model, it was possible to identify correctly all the malignant cases in validation and test set. The result of the multivariate LR analysis was also similar as that of ANN model and all the cases were also classified correctly.Conclusions:In this study, we successfully constructed an ANN model to diagnose metastatic carcinoma in effusion cytology. ANN is very promising in the diagnosis of metastatic carcinoma in effusion cytology. In future, ANN model may help the cytopathologist to diagnose the difficult cases in effusion fluid. © 2011 International Clinical Cytometry Society