bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of mechanochemically modified MoO 3 -ZnO on Mo supply to plants when co-granulated with macronutrient fertilizers
Authors: Zheng Bo , Degryse Fien , Andelkovic Ivan B. , Baird Roslyn , McLaughlin Mike John 
Published: June 2024

Abstract

Molybdenum (Mo) is an essential micronutrient required for plant growth but is prone to leaching from neutral and alkaline soils. The use of slow-release Mo sources could potentially reduce leaching losses from soils and increase crop yields. In this study, we assessed mechanochemistry as a green method to produce slow-release Mo sources. Molybdenum compounds (MoO3 or (NH4)6Mo7O24·4H2O) were mechanochemically (MC) treated with ZnO to synthesize compounds with a Mo content of 1–36%. Reduced Mo solubility after MC treatment, compared to the initial Mo source, was obtained with the MoO3 source and these composites were used for co-compaction with macronutrient fertilizers. Macronutrient pellets with 0.2% Mo were compacted using the 4% Mo and 36% Mo (characterized as ZnMoO4) compounds. A column dissolution test showed that the 4% Mo compound in a macronutrient carrier (DAP and MAP) only released around 40% of the total Mo compared to 80% for a non-MC treated control over 72 h. Column leaching using two soils revealed that the release behavior of Mo was strongly related to the pH of the leachate, which was affected by both the soil pH and the macronutrient carrier. More Mo was released when the MC-treated compound was co-compacted with diammonium phosphate (DAP) compared to monoammonium phosphate (MAP). The MC-treated compound with 4% Mo showed significantly less leaching than the control without ball milling when co-compacted with both MAP and DAP. In a pot trial with simulated leaching, the uptake of Mo was greater for the MC-treated 4% Mo compound co-compacted into DAP than for the other Mo sources. Overall, our results indicate that MC-treated MoO3-ZnO could be used as a slow-release Mo source in high-rainfall areas.
Screening and identification of immunoinfiltrating genes associated with the prognosis and construction of the regulatory axis of competitive endogenous RNA of hepatocellular carcinoma
Authors: Zhang Xu , Wu Li-Na , Feng Xue-Yan , Ma Li-Na , Ding Xiang-Chun , Ma Zi-Min , Hai Long 
Published: June 2024

Abstract

Background
Hepatocellular carcinoma (HCC) progression is closely associated with tumor immune cell infiltration, a process influenced by the abnormal expression of non-coding RNAs (ncRNAs). These ncRNAs play a pivotal role in regulating immune infiltration in HCC, thereby providing insights into RNA interactions in this context.
Aims
This study aims to discover new RNA transcripts and develop potential competitive endogenous RNA (ceRNA) networks that influence immune infiltration and the prognosis of HCC patients.
Method
We performed lncRNA-mRNA chip sequencing on cancerous and adjacent tissues from three HCC patient pairs to profile differentially expressed genes (DEGs), including mRNAs and lncRNAs. Collaborating with the TCGA database, we identified miRNAs that bind to these transcripts and analyzed the DEGs' expression profiles. The study included GO and KEGG functional enrichment analyses of DEGs. Furthermore, we constructed a ceRNA network using R software to explore the relationship between key genes and immune cell infiltration and their impact on HCC patient prognosis.
Results
A ceRNA sub-network involving 8 lincRNAs, 4 miRNAs, and 18 mRNAs associated with HCC immune infiltration was established. We identified four immune-related hub genes (CD3G, CD8B, IL7R, and SHC1) linked to HCC prognosis. CD3G, CD8B, and IL7R emerged as protective factors, whereas SHC1 was identified as a risk factor. Kaplan-Meier survival analysis showed that higher expression levels of CD3G, CD8B, and IL7R correlate with longer survival in HCC patients, while increased SHC1 expression is associated with reduced survival time.
Conclusion
The constructed lncRNA-miRNA-mRNA ceRNA network highlights four critical genes that may regulate immune infiltration in HCC. This study sheds light on the post-transcriptional regulatory role of lncRNAs in HCC and lays the groundwork for identifying novel targets for HCC immunotherapy.
The Short-Term Effect of Interactive Drama and Reflective Writing on Adolescents’ Social-Emotional Learning Core Competencies: A Five-Week Intervention
Authors: Mahmoud Ammar 
Published: June 2024

Abstract

Acting on stage can boost adolescents’ confidence and compassion towards their peers. When an adolescent plays different roles in a performance, they can develop empathy and gain insight into their lives and the lives of others. Understanding the role of theatre at schools can support promoting social change through knowledge generated from students’ experiences. In this study, interactive theatre and reflective writing were used as an intervention to promote Social Emotional Learning (SEL) core competencies. Seven adolescents between the ages of 11 and 15 participated in the study over five weeks at a language school in Yerevan, Armenia. The findings show that the intervention helped develop the participants’ SEL competencies of SelfAwareness, Relationship Skills, and Social Awareness, while Self-Management and Responsible Decision-Making remained almost unchanged.
Patterns of balancing and compensating primary tooth extractions amongst paediatric dentists
Authors: Nalbantoglu Eser , Singh Parmjit 
Published: June 2024

Abstract

Introduction: Balancing and compensating extractions (BCEs) of primary teeth aims to minimize the development of more severe malocclusions and reduce the need for subsequent complex orthodontic treatment.
Purpose: To assess the demographics, practice characteristics, and clinical preferences of United Kingdom (UK) paediatric dentists for BCEs of primary teeth, to determine adherence to national clinical guidelines and whether paediatric dentists refer patients to orthodontists before deciding on BCEs.
Methods: This was a total population online survey of members of the British Society of Paediatric Dentistry (BSPD). A pre-tested, self-administered electronic questionnaire was accessed through a secure website. Questions offered frequency options (always/frequently, often/sometimes and rarely/never) for a range of clinical scenarios in patients up to 5 years and those between 6 and 9 years. Descriptive statistics in the form of percentages were presented. To compare single population/sample percentages, a Pearson Chi-square goodness-of-fit (GOF) test with post hoc pairwise binomial analysis and Bonferroni adjustments was performed.
Results: Of the 288 specialists invited, 67 (23.3%) completed the questionnaire. Respondents were mostly female (n=55; 82.1%), with most respondents working in secondary care (n=51; 77.3%). The majority (n=54; 81.8%) supported the application of guidelines for primary teeth extractions. Thirty-nine paediatric dentists (58.2%) always/frequently encountered BCEs, with 29 (46.2%) performing BCEs in over 40 patients in the past year. Forty respondents (59.7%) reported always/frequently complying with national clinical guidelines for primary teeth extractions. Data from 65 respondents indicates that 83.6% (n=56) rarely/never made referrals to an orthodontist, whilst 65.7% (n=44) rarely/never consulted an orthodontist (p < 0.001).
Conclusions: The results reveal significant decision variation across clinical scenarios, with good adherence to guidelines in BCEs of primary teeth among paediatric dentists. However, there is limited interdisciplinary collaboration, as indicated by the infrequent referrals or consultations with orthodontists when considering BCEs of primary teeth.
Analysis of alcohol consumption on gastric cancer in different infectious states of Helicobacter pylori in the Wuwei population, China.
Authors: Mboté Olivier Bilembi , Feng Boxi , Zhou Yubo , Zhang Mingyu , Wang Yindi , Lv Zhen , Li Sansan , Xie Yahui , Wei Xingmin , Wu Jianjun , Liu Yuqin 
Published: June 2024

Abstract

Aims
The study aims to examine the correlation between alcohol consumption and the risk of gastric cancer in the Wuwei population with different levels of H. pylori infection.
Methods
The study included 3123 participants aged 40–70 years who had resided in Wuwei City for at least 5 years. Participants completed questionnaires on personal information, diet, alcohol consumption, family and medical history, and H. pylori detection. All participants underwent 13C-UBT testing for H. pylori infection, and upper gastrointestinal endoscopy and pathology were performed. Testing was conducted before diagnosis to avoid recall bias.
Results
Alcohol increases the risk of gastric cancer, but it decreases the risk in those who are infected. Those aged 50–70 without H. pylori who consume alcohol and smokers who quit with H. pylori infection have a higher risk of gastric cancer.
Conclusion
Alcohol consumption represents a significant risk factor for the development of gastric cancer. This risk is particularly pronounced with advancing age and following the eradication of H. pylori.
Postoperative inflammatory markers as early predictive factors for prolonged postoperative hospital stay after highly advanced hepatobiliary-pancreatic surgery: A single-center retrospective study
Authors: Fukada Masahiro , Mitsui Noriki , Horaguchi Takeshi , Yasufuku Itaru , Sato Yuta , Tajima Jesse Yu , Kiyama Shigeru , Tanaka Yoshihiro , Murase Katsutoshi , Matsuhashi Nobuhisa 
Published: June 2024

Abstract

Background
Postoperative length of hospital stay (PLOS) is a crucial measure of surgical quality. Prolonged PLOS (PPLOS) escalates treatment costs and delays the transition from surgery to adjuvant chemotherapy. Additionally, PPLOS can negatively affect long-term prognosis. The predictive factors for PPLOS, particularly following highly advanced hepatobiliary-pancreatic surgery (HBPS), have not been thoroughly investigated. In this study, we aimed to identify perioperative predictive factors for PPLOS following highly advanced HBPS.
Methods
This single-center retrospective study enrolled 737 patients at Gifu University Hospital, Japan, who underwent highly advanced HBPS between January 2010 and December 2023. Perioperative predictive factors for PPLOS were evaluated in patients with severe postoperative complications (n = 190; Clavien–Dindo classification grades ≥ III) in univariate and multivariate analyses.
Results
Among the included patients, 97 had PPLOS, and patients with severe postoperative complications had a median PLOS of 40 days. Preoperative body mass index, pancreatic surgery, C-reactive protein to albumin ratio (CAR) on postoperative day (POD)3, and neutrophil to lymphocyte ratio (NLR) on POD3 showed significant correlations with PPLOS in univariate analysis. Multivariate analysis showed that CAR on POD3 (> 5.0, odds ratio [OR], 2.79; 95% confidence interval [CI], 1.32–6.05; p < 0.01) and NLR on POD3 (> 20.0, OR, 2.92; 95% CI, 1.23–7.59; p = 0.01) were independent predictive factors for PPLOS.
Conclusions
Regardless of the type of surgery (hepatobiliary or pancreatic), significant PLOS prolongation was observed following highly advanced HBPS, depending on the presence and severity of postoperative complications. In patients with serious postoperative complications, postoperative inflammatory markers such as CAR and NLR on POD3 may be early predictive factors for PPLOS. This study emphasizes the need for early and effective postoperative management based on inflammatory markers to prevent prolonged severe complications, which can result in shorter PLOS following highly advanced HBPS.
Campylobacter jejuni phages: evaluation and enhancement of antibacterial activity and comprehensive characterization
Authors: Lwin Su Zar Chi , Maung Aye Thida , Linn Khin Zar , Hirono Miku , Shen Cunkuan , El-Telbany Mohamed , Abdelaziz Marwa Nabil Sayed , Mohammadi Tahir Noor , Masuda Yoshimitsu , Honjoh Ken-ichi , Miyamoto Takahisa 
Published: June 2024

Abstract

In this study, Campylobacter jejuni phages were characterized and investigated the combined effects of phages and ethylenediaminetetraacetic acid (EDTA). The antibacterial activity of specific phages with/without EDTA was investigated at multiplicity of infection (MOIs) of 10 and 1000 at both 42 and 4 °C during 48 h of incubation. The phage cocktail with EDTA decreased the viable counts by 1 log and inhibited the regrowth of the phage-resistant population after a 48-h incubation at 42 °C. At 4 °C, a single phage, vB_CjeM-PC10, reduced the viable count of C. jejuni by 3 log and 2 log in Brain Heart Infusion (BHI) broth and on chicken skin, respectively, after incubation for 48 h. Genomic DNA sequence analyses showed that phage vB_CjeM-PC10 had a linear double stranded DNA (dsDNA) of 51,148 bp, and phage vB_CjeM-PC22 had a circular dsDNA comprising 32,543 bp. Since phages are temperate, they are not practically applicable without lysogenic gene disruption by genome editing. However, these findings enrich data resources by highlighting the potential control of C. jejuni infection.
Finite element analysis of thermomechanical responses in biological tissues under varying thermal conductivity
Authors: Abbas Ibrahim , El-Bary Alaa 
Published: June 2024

Abstract

This work offers numerical solutions within the framework of bio-thermoelastic model, addressing the bioheat transfer in living tissues due to laser irradiations, considering varying thermal conductivity. To carry out thermal treatment procedures efficiently, it is crucial to have a comprehensive understanding of both the thermal transmissions mechanism and the subsequent mechanical and thermal interactions within the living tissues of the patient. Evaluating thermal injurie to the tissue requires assessing the extent of denatured proteins, employing the Arrhenius relation. Given the nonlinearity of the fundamental formulations, the finite element technique is employed to address and solve this problem. Graphical depictions of the numerical result portray the change in temperature, displacement, stress, and thermal damages in response to variations in thermal conductivity and thermal relaxation time. The findings obtained using the finite element approach are additionally compared with data from a pre-existing experimental data, confirming the numerical calculation accuracy through cross-referencing.
A novel endotracheal intubation method based on magnetic-guided technology
Authors: Chen Bowen , Wang Rongfeng , Song Weilun , He Rongxin , Liu Wuming , Zhang Wei , Ma Feng , Lyu Yi , Dong Dinghui 
Published: June 2024

Abstract

BACKGROUND
Endotracheal intubation (ETI) is a crucial skill for airway management in anesthesia and emergency. The classic ETI based on laryngoscopy have limitations in learning curve, respiratory exposure risk and difficult airway. Magnetic-guided technique was based on the non-contact force and has been successfully used in laparoscopy and endoscopy to simplify operation and improve effectiveness. Therefore, we introduce magnetic-guided device of ETI for the first time, developing a magnetic-guided ETI method.
METHODS
The magnetic-guided ETI device consisted of a magnetic guidewire and an external magnet (EM). For the novel device, the control parameter (working distance) is determined by force and anatomic parameters. The former was investigated by test bench, and the later was measured through CT graph. Then 30 undergraduates without prior ETI training divided into medical and non-medical group according the participant’s major. Both subgroups underwent ETI training with classic and magnetic-guided methods. Magnetic-guided ETI also be tested in difficult airway module. The first-attempt success rate, total intubation time and 5-point Likert scale of difficulty were recorded for assessments.
RESULTS
We obtained the magnetic force and the tip deflection angle-distance curves of magnetic-guided ETI device. In addition, the surface distance is 32.45 ± 5.24mm, and the deflection angle is 35.4 ± 7.6°. Thus, the working distance for the novel device is 40–60 mm. Magnetic-guided ETI was completed without close and direct exposure to patient’s oral cavity. Compared with classic method, it got a higher first-attempt success rate (magnetic-guided vs classic: 80.0% vs. 66.7%, p<0.05) and less total intubation time (magnetic-guided vs classic: 42.5 ± 2.7s vs 49.4 ± 5.7s, p<0.01) in normal module. In addition, most subjects indicated magnetic-guided ETI is easier than classic method. This is more evident in the Non-medical Group (magnetic-guided vs classic: 2.8 ± 0.8 vs 3.3 ± 0.7, p<0.01). Even in difficult airway, magnetic-guided method still got a higher first-attempt success rate (magnetic-guided vs classic: 73.3% vs 53.3%, p<0.05) and less total intubation time (magnetic-guided vs classic: 45.3 ± 3.7s vs 53.4 ± 3.5s, p<0.01) than classic method.
CONCLUSION
Magnetic-guided ETI was a simple, safe and effective method. Compared with former work, it is friendlier to non-medical persons and effective for difficult airway. It also avoids direct and close respiratory exposure during operation. The use of the magnetic-guided ETI device can enhance the safety and efficiency of airway management, making it an effective tool for non-medical persons to rapidly perform ETI.
Long-term Outcomes of High Tibial Osteotomy vs. Unicompartmental Knee Arthroplasty: A Retrospective Study
Authors: Özgözen Alaaddin Levent , Çınar Bekir Murat 
Published: June 2024

Abstract

Background:High tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA) are surgical interventions commonly used for medial compartment knee osteoarthritis. Despite their widespread use, there remains uncertainty regarding their comparative effectiveness and long-term outcomes.This study aimed to retrospectively compare HTO and UKA surgeries in terms of clinical, radiological, survival, revision implants, and complications.MethodA retrospective evaluation was conducted on 51 HTO and 87 UKA patients operated on between 2004 and 2014, with an average follow-up period of 11.3 years. Patients were compared clinically using the Oxford Knee Score (OKS) and radiologically using the hip-knee-ankle angle (HKA) values at postoperative year 1 and at the final follow-up. In addition, both techniques were compared in terms of survival rates, complication rates, and the materials used when revisions were necessary.ResultNo significant difference was observed in the OKS values between HTO and UKA at postoperative year 1 and at the final follow-up. It was observed that HTO corrected the alignment better initially, but in the final follow-up, both surgeries showed a recurrence of alignment deviation towards varus. In comparison to UKA, HTO surgery exhibited a higher complication rate; however, there was no statistically significant difference between the two surgeries (15.4% vs 9.2%, p=0.284). However, in UKA patients, the need for revision to total knee arthroplasy (TKA) was notable when complications arose. There was no statistical difference in survival rates between the two surgical techniques. The 5, 10, and 15-year survival rates for HTO and UKA were found to be 96%, 82%, 61% and 91%, 83%, 74%, respectively. Significantly, there was a greater need for tibial stem in revision cases of UKA patients. (42,1% vs 0% p<0,001).ConclusionBoth surgical techniques yield similar results in terms of clinical outcomes, survival, and complication development. However, when complications occur in UKA, there may be a need for revision to TKA, and UKA patients may require a tibial stem during TKA revision.
A systematic review of the performance of Artificial Intelligence for automated DWI/FLAIR mismatch evaluation on MRI in ischemic stroke
Authors: Soltanali Zahra , Pourrahim Alireza , Williams Chelsea Ruth-Ann , Ekvan Mohammad Hossain , Ahmadi Iraj , Raiesi Omid 
Published: June 2024

Abstract

The purpose of this study was to survey the existing artificial intelligence (AI) algorithms created for the automated detection of the diffusion-weighted imaging (DWI)–fluid-attenuated inversion recovery (FLAIR) mismatch and assess how their performance compares to that diagnostic techniques performed by neuroradiologists. The literature search for this systematic review was conducted in PubMed, MEDLINE, Ovid Embase, Web of Science, Scopus, and Cochrane databases up until February 2, 2024. The review team cross-checked the reference lists of the included studies to identify any additional relevant references, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We assessed the included studies using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. The area under the curve (AUC) was reported in most studies, However, one study did not report this metric, The AI models achieved AUCs between 0.60 and 0.90, Sensitivity ranged from 0.6 to 0.9, and specificity ranged from 0.72 to 0.99, the positive predictive value (PPV), negative predictive value (NPV) and F1-Score were ranging from 0.72 to 0.93, 0.47 to 0.91 and 0.65 to 0.9, respectively. Additionally, the dice similarity coefficients (DSC) 0.73 & 0.8 were stated in two researches and accuracies ranging from 0.67 to 0.99. This review indicates that the current AI methods for DWI/FLAIR mismatch assessment may not be able to accurately determine the time since stroke onset based only on the DWI and FLAIR sequences, however, an AI-based approach focused on treatment eligibility, outcome prediction, and incorporating patient-specific information could potentially improve the care of stroke patients.
The association of the Dietary Inflammatory Index (DII) with spexin level, metabolic syndrome and some inflammatory biomarkers in children with obesity: a cross-sectional study
Authors: Behrooz Maryam , Hajjarzadeh Samaneh , Moludi Jalal , Bakhshimoghaddam Farnush , Ostadrahimi Alireza 
Published: June 2024

Abstract

Objectives
Chronic low-grade diet-related inflammation was indicated to affect obesity and metabolic syndrome (MetS). The current study was designed to explore the Dietary Inflammatory Index (DII®) in children and its relationship with spexin level, appetite, obesity, MetS, insulin resistance, and some inflammatory biomarkers.
Methods
The present study was conducted on 189 children. All study variables were assessed using standard techniques. The overall dietary intakes of participants were applied to calculate DII scores.
Results
Mean (SD) of children’s DII score was − 1.25 (1.01). A higher DII score was associated with higher odds of obesity and HDL abnormality (P < 0.05). The subjects categorized in the first tertile of the DII score (the lowest value and more anti-inflammatory) had 79.49 pg/ml higher spexin level, 260.27 pg/ml higher IL-10 levels, and 3.03-unit lower appetite score in comparison to the third tertile in the crude model (P < 0.05). These findings remain significant only for spexin in the adjusted model. Also, a significant correlation was observed between the DII score and the hs-CRP level.
Conclusion
This data suggests that the effect of DII on obesity can be largely attributed to spexin levels, inflammatory markers, and appetite scores rather than its effect on MetS components.