bluuebunny/crossref_metadata_2025_split huggingface dataset:
One way or another…or both: Different roles of fathers, mothers, and adolescents in the intergenerational transmission of inclusive attitudes
Authors: Maratia Fabio , Crocetti Elisabetta 
Published: June 2024

AbstractThis study aimed to examine the processes of intergenerational transmission of attitudes toward migrant integration policies in families with adolescents. Participants included 809 adolescents (M
age = 15.61, range: 13.87–20.04 years), 545 fathers (M
age = 51.19, range: 38–77 years), and 716 mothers (M
age = 48.11, range: 33–68 years) involved in a longitudinal study with two assessments and a time‐lag of 1 year between them. Each family member completed the Attitudes towards Migrant Integration Policies scale. In addition, adolescents reported their perception of discussion of current events with parents and the level of support they receive from them. The cross‐lagged model highlighted a unidirectional transmission, with fathers' but not mothers' attitudes toward migrant integration policies influencing adolescents' attitudes. Furthermore, it has been examined which factors can either amplify or reduce the strength of intergenerational transmission processes considering individual characteristics of both adolescents (i.e., sex, age) and their parents (i.e., political orientation), and cultural (i.e., family, ethnic background) and relational (i.e., discussion of current events, perceived support from fathers and mothers) family characteristics. Individual factors (i.e., fathers' political orientation) and family relational characteristics (i.e., perceived support from fathers) moderated the transmission processes. The transmission was bidirectional when fathers reported being left‐wing and politically oriented and stronger when adolescents reported high support from their fathers. Thus, this study underscores the complexity of the family context, highlighting that the transmission of inclusive attitudes does not always operate in one way (e.g., from parents to children) or another, but in some cases, simultaneously.
GhHAM regulates GoPGF‐dependent gland development and contributes to broad‐spectrum pest resistance in cotton
Authors: Long Lu , Xu Fu‐Chun , Yuan Man , Shang Shen‐Zhai , Song Hao‐Ge , Zhao Jing‐Ruo , Hu Gai‐Yuan , Zhang Zhen‐Nan , Zhao Xiao‐Tong , Ma Jia‐Yi , Hussain Amjad , Wang Ping , Cai Ying‐Fan , Jin Shuang‐Xia , Gao Wei 
Published: June 2024

SUMMARYCotton is a globally cultivated crop, producing 87% of the natural fiber used in the global textile industry. The pigment glands, unique to cotton and its relatives, serve as a defense structure against pests and pathogens. However, the molecular mechanism underlying gland formation and the specific role of pigment glands in cotton's pest defense are still not well understood. In this study, we cloned a gland‐related transcription factor GhHAM and generated the GhHAM knockout mutant using CRISPR/Cas9. Phenotypic observations, transcriptome analysis, and promoter‐binding experiments revealed that GhHAM binds to the promoter of GoPGF, regulating pigment gland formation in cotton's multiple organs via the GoPGF‐GhJUB1 module. The knockout of GhHAM significantly reduced gossypol production and increased cotton's susceptibility to pests in the field. Feeding assays demonstrated that more than 80% of the cotton bollworm larvae preferred ghham over the wild type. Furthermore, the ghham mutants displayed shorter cell length and decreased gibberellins (GA) production in the stem. Exogenous application of GA3 restored stem cell elongation but not gland formation, thereby indicating that GhHAM controls gland morphogenesis independently of GA. Our study sheds light on the functional differentiation of HAM proteins among plant species, highlights the significant role of pigment glands in influencing pest feeding preference, and provides a theoretical basis for breeding pest‐resistant cotton varieties to address the challenges posed by frequent outbreaks of pests.
Real-Time Estimation of Human Arm Dynamic Parameters Based on Optical
Authors: Xu Yang , Wen Jiayi , Liu Chengcheng , Liu Zhu , Zhu Peiyi 
Published: June 2024

Abstract
A flexible optical intensity sensor is designed in this study to address the poor adaptability of fixed-value parameters in exoskeleton research, which makes it difficult to handle system changes and uncertainties. The light transmission portion of the sensor is made of TPU and PET, exhibiting flexibility and bendable deformation characteristics, as well as good sensitivity, anti-interference capability, and stability. The flexible optical sensor is fixed on the side of the binding device, which is installed on the biceps brachii to collect the optical intensity loss signals after sensor bending. By utilizing this method, parameters such as the cross-sectional radius, arm centroid, and moment of inertia can be estimated in real-time. Finally, the estimated radius values are compared with theoretical values, and the accuracy is verified by combining the kinematic model. Experimental results demonstrate that the proposed method achieves a parameter information error of less than 8.63% and a stability better than 4.3%. Compared to the traditional fixed parameter method, the stability has improved by 25.06%, and the accuracy has improved by 9.04%.
Overexpression of
ATP5F1A
in Cardiomyocytes Promotes Cardiac Reverse Remodeling
Authors: Xu Mengda , Zhang Hang , Chang Yuan , Hua Xiumeng , Chen Xiao , Sheng Yixuan , Shan Dan , Bao Mengni , Hu Shengshou , Song Jiangping 
Published: June 2024

BACKGROUND:
The mechanism of cardiac reverse remodeling (CRR) mediated by the left ventricular assist device remains unclear. This study aims to identify the specific cell type responsible for CRR and develop the therapeutic target that promotes CRR.

METHODS:
The nuclei were extracted from the left ventricular tissue of 4 normal controls, 4 CRR patients, and 4 no cardiac reverse remodeling patients and then subjected to single-nucleus RNA sequencing for identifying key cell types responsible for CRR. Gene overexpression in transverse aortic constriction and dilated cardiomyopathy heart failure mouse model (C57BL/6J background) and pathological staining were performed to validate the results of single-nucleus RNA sequencing.

RESULTS:

Ten cell types were identified among 126 156 nuclei. Cardiomyocytes in CRR patients expressed higher levels of
ATP5F1A
than the other 2 groups. The macrophages in CRR patients expressed more anti-inflammatory genes and functioned in angiogenesis. Endothelial cells that elevated in no cardiac reverse remodeling patients were involved in the inflammatory response. Echocardiography showed that overexpressing
ATP5F1A
through cardiomyocyte-specific adeno-associated virus 9 demonstrated an ability to improve heart function and morphology. Pathological staining showed that overexpressing
ATP5F1A
could reduce fibrosis and cardiomyocyte size in the heart failure mouse model.

CONCLUSIONS:

The present results of single-nucleus RNA sequencing and heart failure mouse model indicated that
ATP5F1A
could mediate CRR and supported the development of therapeutics for overexpressing
ATP5F1A
in promoting CRR.
Bacterial profile and antibiotic susceptibility patterns in patients with secondary peritonitis: a cross-sectional study in Uganda
Authors: Godefroy Nyenke Bassara , Muhumuza Joshua , Molen Selamo Fabrice , Waziri Musa Abbas , Kagenderezo ByaMungu Pahari , Vahwere Bienfait Mumbere , Sikakulya Frank Katembo , Mauricio William , Wandabwa Joel , Francois Bisingurege Kagoro , Agwu Ezera , Okedi Xaviour Francis 
Published: June 2024

Abstract
Introduction
Secondary peritonitis is the second leading cause of sepsis worldwide. Drug resistance to peritoneal cavity bacterial infection remains a public health threat, especially in resource-limited settings in Africa, including Uganda. This study aimed to determine the antibacterial susceptibility patterns and factors associated with secondary peritonitis among patients with acute abdomen who underwent surgery at a Regional Referral Hospital in Uganda.

Methods
This was a cross-sectional study conducted at Hoima Regional Referral Hospital (HRRH) that enrolled 126 patients with acute abdomen. Clinical samples were aseptically collected at laparotomy from patients with secondary peritonitis for culture and sensitivity using standard Microbiological methods. Binary logistic regression was used to identify factors associated with secondary peritonitis among patients with acute abdomen.

Results
The majority of the patients were males (61.9%) with a mean age of 37.9(SD ± 21.8). Secondary peritonitis was found in 57(45.2%) of the patients. Gram-negative bacteria were the most commonly isolated organisms with Escherichia coli (35.8%) and Klebsiella spp (17.0%) predominating. Imipenem 88.8%(8/9), Amikacin 88.8%(8/9), Ciprofloxacin 44.4%(4/9) and Gentamicin 44.4%(4/9) demonstrated sensitivity to the different isolated organisms at varying degrees. Being a male (AOR = 3.658; 95% CI = 1.570–8.519, p = 0.003) and presenting 3 days after onset of symptoms (AOR = 2.957; 95% CI = 1.232–7.099, p = 0.015) were independently associated with secondary peritonitis.

Conclusion
Imipenem, Amikacin, Ciprofloxacin, and Gentamicin should be considered for empirical therapy in cases of secondary peritonitis. Patients, more especially males with abdominal pain should be encouraged to present early to the hospital to minimize progression to secondary peritonitis.
Impact of the IDEA Collaboration Study on Real-World Practice Patterns of Adjuvant Chemotherapy in Patients With Stage III Colon Cancer: A Population-Based Study
Authors: Samnani Sunil , Ding Philip Q. , Lee-Ying Richard , Cheung Winson Y. , Karim Safiya 
Published: June 2024

PURPOSE
The International Duration Evaluation of Adjuvant Chemotherapy (IDEA) collaboration showed no significant clinical difference in outcomes in patients with stage III colon cancer (CC) treated with 3 versus 6 months of oxaliplatin-based adjuvant chemotherapy (O-ACT). We aimed to assess change in real-world practice patterns before and after publication of the IDEA study.

METHODS
This retrospective cohort study included patients age ≥18 years with stage III CC diagnosed between January 1, 2012, and December 31, 2020. Eligible patients received >1 dose of ACT between March 20, 2012, and May 10, 2021 inclusive. They were categorized into pre-IDEA (diagnosed before March 31, 2018) and post-IDEA (diagnosed on or after April 1, 2018) groups. The primary outcome was the median duration and type of ACT and factors associated with a shorter duration. Secondary outcomes were 2-year overall survival (OS) and cancer-specific survival (CSS).

RESULTS

In total, 740 patients were included (median age, 64 years, range, 27-90; 52.7% male). 48.8% had pT4 and/or pN2 disease. 77% received O-ACT. In the post-IDEA era, capecitabine plus oxaliplatin (CAPOX) ACT use increased (22.8%-50.7%,
P
< .001), and median duration of treatment was significantly shorter (2.7
v
4.8 months,
P
< .001). Factors associated with shorter O-ACT duration included diagnosis in the post-IDEA era (odds ratio, 2.08,
P
= .002), absence of pT4 and/or pN2 disease (hazard ratio [HR], 1.71,
P
= .01), and receipt of CAPOX (HR, 2.58,
P
< .001). Two-year OS and CSS were comparable between pre- and post-IDEA eras (OS 95%
v
94%; CSS 96%
v
96%).

CONCLUSION
Our study shows that the results of the IDEA trial have been largely adopted in clinical practice with shorter duration of ACT in low-risk stage III CC.
Comparison of the effectiveness of ultrasound-guided radiofrequency ablation and conventional open thyroidectomy in the treatment of benign thyroid nodules
Authors: Fu Yuehe , Xia Yuke , Wang Haiyan , Zhang Gong 
Published: June 2024

Objective: To compare the effectiveness of ultrasound (US)-guided radiofrequency ablation (RFA) and conventional open thyroidectomy (OT) in the treatment of benign thyroid nodules (BTN).
Methods: Medical records of 103 patients with BTN undergoing surgical treatment at The Affiliated Jiangning Hospital of Nanjing Medical University from March 2019 to March 2022 were retrospectively analyzed. Records show that 53 patients underwent US-guided RFA (observation group) and 50 patients underwent conventional OT (control group). Perioperative indicators (operation duration, intraoperative blood loss, postoperative hospital stay, incision length, and VAS score 12h and 24h after surgery), complications, thyroid function, and nodule recurrence in both groups were compared and analyzed.
Results: Perioperative indicators of patients in the observation group were better, and the visual analogue scale (VAS) scores at 12 and 24 hours after the surgery were lower than those of the control group (p<0.05). The incidence of complications in the observation group was significantly lower than that in the control group (p<0.05). There was no statistically significant difference in the preoperative levels of thyroid-stimulating hormone (TSH), serum free thyroxine (FT4) and serum free triiodothyronine (FT3) between the two groups (p>0.05). The postoperative TSH levels in the observation group increased compared to the preoperative levels and were higher than those in the control group, while FT4 and FT3 levels decreased after surgery and were lower than those in the control group (p<0.05).
Conclusions: Compared to conventional open thyroidectomy, US-guided RFA is associated with less trauma, faster recovery, fewer complications, and less impact on thyroid function in the treatment of patients with BTN.
doi: https://doi.org/10.12669/pjms.40.7.9486
How to cite this: Fu Y, Xia Y, Wang H, Zhang G. Comparison of the effectiveness of ultrasound-guided radiofrequency ablation and conventional open thyroidectomy in the treatment of benign thyroid nodules. Pak J Med Sci. 2024;40(7):---------. doi: https://doi.org/10.12669/pjms.40.7.9486
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Charles Correa e il Mandala. Un altro "mindset"
Authors: Manuela Schirra  
Published: June 2024

A partire dall’hyper-local Correa intercetta l’innovazione e lascia la sua lectio. “Usando con disinvoltura l’antico mandala come base per un edificio contemporaneo, è possibile arrivare ad un concetto completamente nuovo di organizzazione di sequenze spaziali”.* Un dispositivo reiterato e da reiterare secondo un sistema di ‘mondi di mondi’, sviluppato secondo la tecnica del ‘incastro’ e fondato sul presupposto del ‘vuoto’ come organizzatore e generatore spaziale.
La porta del Pantheon, il ‘muro’ di Alberti e quello di Chillida. Forme dell’ipogeo e l’architettura degli spazi cavi
Authors: Giuseppe Ferrarella  
Published: June 2024

Nessuna forma e nessun tipo sembrano potersi ricondurre univocamente alle architetture del sacro, eppure molti di questi siti posseggono un carattere comune: l’idea dello spazio ipogeo. Se in alcuni di questi luoghi – soprattutto i più antichi – lo spazio è prodotto di un reale movimento materico, in altri – più recenti – ciò è riprodotto dalle forme massive, dalle logiche di sottrazione dei volumi, dalla concezione dello spazio come luogo ‘cavato dal pieno’. È difficile, se non impossibile, risalire alle origini di questa esigenza apparentemente comune a molte culture, e sebbene sia affascinante pensare che tutto ciò abbia genesi nel gesto dello scavo delle prime tombe, l’ipotesi rimarrebbe indimostrabile. Attraverso tre rapide incursioni, si tenterà una riflessione sul senso dello spazio nei luoghi deputati al sacro ed al rito.
Cyberpsychology: The Understanding of Woman-Social Media's Interaction
Authors: Lailisna Novi Nur 
Published: June 2024

The face can display how the emotion of a human. Some research concluded that it is possible to be different details of emotion and event. As found in the gender studies, men and women are having professional anger in both statuses for their own emotions. Especially for women who are actively become netizens of social media such as Facebook, Twitter, and Instagram are predictively more interactive in that media and have various emotions to say and receive anything from them. The critical introduction of social media from N. Bakić-Mirić explained a wide variety of topics including how to define the characteristics of new media; social and political uses of new media and new communications; new media technologies, politics, and globalization; everyday life and new media; theories of interactivity, simulation, the new media economy; cybernetics, cyberculture, the history of automata and artificial life. Therefore, more specifically, women have the psychology of becoming women in social media. Applying qualitative methodology, this study explores what cyberpsychology extend to women and how their emotion be on social media. The research contributes to women on to be careful with social media.
[Wajah pada kesempatannya mampu menampilkan bagaimana emosi manusia. Beberapa penelitian menyimpulkan bahwa terdapat kemungkinan adanya emosi dan peristiwa tertentu dalam konteks yang berbeda. Sebagaimana dalam studi gender, pria dan wanita mengalami kemarahan yang bermakna dari ungkapan untuk emosi mereka sendiri. Khususnya bagi perempuan yang aktif menjadi warganet di media sosial seperti facebook, twitter dan instagram; perempuan diprediksi lebih interaktif dalam media tersebut dan memiliki berbagai emosi untuk menyampaikan dan menerima apa pun dari. Pengenalan kritis media sosial dari N. Bakić-Mirić dijelaskan dalam berbagai topik termasuk: bagaimana mendefinisikan karakteristik media terbarukan; penggunaan media baru dan komunikasi baru secara sosial dan politik; teknologi media baru, politik dan globalisasi; kehidupan sehari-hari dan media baru; teori interaktivitas, simulasi, ekonomi media baru; sibernetika, budaya siber, sejarah automata dan kehidupan buatan (maya). Oleh karena itu, terkhusus lagi, perempuan memiliki psikologinya sendiri untuk menjadi perempuan di media sosial. Menerapkan metodologi kualitatif, studi ini mengeksplorasi pertanyaan penelitian seperti: apa pengertian psikologi-siber yang terdapat pada perempuan dan bagaimana emosi mereka di media social. Hasil dari penelitian ini, adalah memberikan wawasan kepada wanita agar lebih peduli pada dirinya sendiri dalam penggunaan media sosial.]
Could this be next for corpus linguistics? Methods of semi-automatic data annotation with contextualized word embeddings
Authors: Fonteyn Lauren , Manjavacas Enrique , Haket Nina , Dorst Aletta G. , Kruijt Eva 
Published: June 2024

Abstract
This paper explores how linguistic data annotation can be made (semi-)automatic by means of machine learning. More specifically, we focus on the use of “contextualized word embeddings” (i.e. vectorized representations of the meaning of word tokens based on the sentential context in which they appear) extracted by large language models (LLMs). In three example case studies, we assess how the contextualized embeddings generated by LLMs can be combined with different machine learning approaches to serve as a flexible, adaptable semi-automated data annotation tool for corpus linguists. Subsequently, to evaluate which approach is most reliable across the different case studies, we use a Bayesian framework for model comparison, which estimates the probability that the performance of a given classification approach is stronger than that of an alternative approach. Our results indicate that combining contextualized word embeddings with metric fine-tuning yield highly accurate automatic annotations.
Уголовный проступок: новые грани российского законодательства
Authors: Gavrilov Boris , Krymov Vitaliy , Shpagina Yuliya 
Published: June 2024

В контексте реформ современного российского уголовного законодательства одним из ключевых направленяий являются вопросы либерализации уголовной ответствен-ности, включая декриминализацию ряда преступлений, снижение уголовно-правовых санкций за отдельные виды противоправных деяний, исключение квалифицированных признаков неоднократности и повторности и ряд др . Особое место в затронутых вопросах занимает введение в российское законодательство уголовного проступка, в связи с чем возникает целый комплекс подлежащих обсуждению и разрешению вопросов, имеющих, в том числе и междисциплинарный характер . В настоящей научной статье авторами с применением научного методологического инструментария раскрыта в теоретико-прикладном аспекте заявленная проблематика и предложены пути ее решения . На примере исторического осмысления делается вывод о том, что российскому уголовному законодательству идея об уголовном проступке не нова и в современной действительности имеются все предпосылки к возвращению его концепции, что подкреплено доводами авторов, а также результатами других научных исследований . Цель исследования состоит в научно-теоретическом обосновании необходимости совершенствования уголовно-правового законодательства, включая выработку законодательных предложений по внесению изменений в уголовное и уголовно-процессуальное законодательство, направленных на защиту прав и законных интересов участников уголовного судопроизводства, а также на производство по уголовному делу в разумный срок . Методы исследования: диалектический, формально-логический, конкретно-социологический, историко-правовой, статистический, контент-анализ, юридико- технический анализ . Проведенное исследование позволило авторам сформулировать вывод о том, что совершенствование уголовно-правового законодательства видится в контексте дифференциации противоправных деяний на уголовные проступки и преступления и введение в уголовно-процессуальное законодательство для рассматри-ваемой категории деяний — протокольной формы расследования, что в целом призвано повысить уровень правовой и социальной защищенности как лиц и организаций, пострадавших от преступлений, так и лиц, впервые совершивших противоправные деяние, исправление которых возможно без применения мер уголовной репрессии.Для цитирования: Гаврилов Б.Я., Крымов В.А., Шпагина Ю.В. Уголовный проступок: новые грани российского законодательства // Право. Журнал Высшей школы экономики. 2022. Т. 15. № 1. С. 115–139. DOI:10.17323/2072-8166.2022.1.115.139.
Turmeric as a Gut-Microbiota Modulator for Cardio-Metabolic Risk Factors: An Updated Comprehensive Review
Authors: Roshanravan Neda , Fatemeh Askari Sayyedeh , Fazelian Siavash , Morshed Behbahani Bahareh , Arjmand Babak , Namazi Nazli 
Published: June 2024

Turmeric is a medicinal herb with antioxidant and anti-inflammatory components that can affect metabolic parameters via various pathways, including the gut-brain axis. Although positive effects of turmeric on health have been reported, findings are conflicting. Accordingly, the current review aimed to provide an overview of the biochemical and biological characteristics of turmeric and examine the impacts of turmeric on cardio-metabolic risk factors with a special focus on its abilities to modulate gut microbiota. In the present comprehensive review, findings of systematic reviews/narrative reviews, clinical trials, animal, and in vitro studies on turmeric in the English language published between 2010 and March 2023 were summarized. Findings revealed that turmeric is a safe medicinal herb with mild gastrointestinal side effects in some cases. It can help improve the glycemic status, lipid profile, and blood pressure. However, food processing and fermentation can affect the bioavailability of its effective components, including curcumin. Several mechanisms, including those affecting intestinal microbiota diversity, intestinal permeability, inflammatory and oxidative pathways, are proposed for their positive effects on metabolic factors. However, due to high between-study heterogeneity, limited high-quality clinical trials, differences in the duration of the intervention, and the form of turmeric supplement, more studies on each metabolic parameter are needed to determine effective dosages and confirm its efficacy as a complementary therapy to modulate microbiota and cardio-metabolic parameters.