bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reservist families and their understanding of military welfare support as a (non)military family
Authors: Connelly Vincent , Hennelly Sarah , Fear Nicola T. , Morrison Zoe , Gribble Rachael , Smith Joanna 
Published: April 2024

LAY SUMMARY The effectiveness of part-time volunteer reservists relies on their willingness to train in their spare time and be deployed, which is influenced by family support. The military can provide reservist families with welfare and support, but the authors wanted to understand the expectations of, and experiences with, welfare support to UK reservist families. A total of 140 family members (mainly spouses and parents) of part-time reservists completed a bespoke survey, and 33 family members were interviewed in depth. Results confirmed there was low awareness and use of available welfare services. Most did not know how to access support, even during a reservist’s full-time deployment, and had inconsistent local experiences of support. Most reservist families do not identify as military families, have low awareness of family support and welfare, and do not require access to support routinely. More access to information online, more contact with better trained welfare staff, and increased reservist awareness of welfare and support should reduce inconsistencies and improve family satisfaction and reservist retention.
Involving family members in the care of military personnel and Veterans: A decisional counselling intervention
Authors: Maguire Angela M. , Woodbury Kerri-Ann 
Published: April 2024

LAY SUMMARY Changes to health care delivery mean that family members are increasingly called upon to provide informal care for injured or ill military personnel and Veterans. When one family member has a long-term physical or mental health condition, many areas of family life are affected (e.g., emotional functioning, daily activities, family relationships, health and sleep, holidays, care involvement and caregiving support, work and study, and finances). One way to better support families is to meaningfully involve them in care planning and coordination. This article discusses some of the challenges that practitioners and families face when working as partners in care. It also offers practitioners a way to talk with military personnel and Veterans about the value of sharing their health-related information with family members.
Impacts of climate change on the Russian economy: Ranking of regions by adaptation needs
Authors: Макаров И.А. , Чернокульский А.В. 
Published: April 2024

Изменение климата, на территории России протекающее быстрее, чем в среднем по миру, сопряжено со значительным потенциальным ущербом для населения и экономики. Для минимизации этого ущерба необходима система адаптационных мероприятий. С учетом разнообразия климатических и экономических условий на территории России, а также в условиях ограниченных ресурсов для реализации таких мероприятий важно выстраивать приоритеты, в том числе выявлять те субъекты федерации, которые сталкиваются с наиболее высоким уровнем климатических рисков. В данном исследовании составлен рейтинг регионов по уровню физических рисков изменения климата и необходимости адаптации к ним. Рейтинг построен с использованием аналитической схемы «воздействие — подверженность — уязвимость» и основан на ранжировании регионов с учетом каждого из этих компонентов климатического риска. Рейтинг представ- лен для четырех ключевых типов воздействия изменения климата: влияния аномально высокой температуры воздуха на здоровье городского населения; влияния засух на сельское хозяйство; учащения лесных пожаров и таяния вечной мерзлоты. Полученные нами результаты представлены отдельно для регионального и федерального уровней целеполагания; они дают объективную основу для расстановки приоритетов финансирования адаптационных мероприятий.
Climate change makes Russia warming faster than global average that is associated with the significant potential damage for its population and economy. To minimize this damage, the system of adaptation measures is needed. Taking into consideration the diversity of climate and economic conditions across the Russian territory and given the scarcity of resources for implementing such measures, their prioritization is necessary, that means revealing of those regions which face the highest level of climate change-related risks. This study proposes the rating of the Russian regions by the level of physical risks of climate change and the need for adapting to them. Rating is built with the use of the analytical framework “hazard — exposure — vulnerability” and is based on ranging the Russian regions by each of these components of climate risk. Rating is composed for four crucial climate-change related hazards: the impact of heat waves on the health of urban population, the impact of droughts on agriculture, rising frequency of forest fires, and melting permafrost. The results of the study are presented separately for regional and federal level of policy and provide the objective base for the prioritization of adaptation measures funding.
SISTEM PENGELOLAAN PENGGAJIAN PENDIDIK DAN TENAGA KEPENDIDIKAN DI SD NEGERI BABAT JERAWAT II
Authors: Agustiah Hanifa Rahma , Ghaisani Aisyah Aaqila , Trihantoyo Syunu 
Published: April 2024

Penggajian guru dan tenaga kependidikan merupakan bagian penting dari sistem Pendidikan karena guru dan tenaga kependidikan merupakan aset utama dalam menyediakan Pendidikan yang berkualitas. Penelitian ini bertujuan untuk menganalisis sistem pengelolaan penggajian guru dan tenaga kependidikan di SD Negeri Babat Jerawat II. Penelitian ini menggunakan metode deskriptif kualitatif. Hasil penelitian yang telah dilakukan didapatkan hasil bahwa penggajian pendidik dan tenaga kependidikan di SD Negeri Babat Jerawat II berasal dari dinas pendidik dan nominalnya pun telah ditentukan oleh dinas Pendidikan, gaji yang diberikan pihak dinas Pendidikan kepada pihak sekolah akan langsung diberikan kepada para pendidik dan tenaga kependidikan, sehingga penggajian di SD Negeri Babat Jerawat II tidak memiliki masalah. Ada beberapa peraturan dan kebijakan yang mempengaruhi penggajian guru dan tenaga kependidikan, seperti Upah Minimum Regional (UMR), Peraturan Daerah, dan Peraturan Menteri Pendidikan dan Kebudayaan. Penggajian guru dan tenaga kependidikan di sekolah dikelola oleh beberapa orang salah satunya adalah bendahara sekolah yang merupakan orang yang bertanggung jawab atas pengelolaan keuangan sekolah, termasuk penggajian guru dan tenaga pendidik.
Exploring the potential of pomegranate (Punica granatum) peel extract and punicalagin as novel anti-hypercholesterolemic agents
Authors: Dehghani Parva , Masjedi Motahareh , Shariati Laleh , Vaseghi Golnaz , Dana Nasim , Zeinalian Mehrdad , Asgary Sedigheh 
Published: April 2024

Background: Hypercholesterolemia, characterized by elevated low-density lipoprotein (LDL) cholesterol levels, is a significant risk factor for cardiovascular diseases. Familial and behavioral factors contribute to its onset, and while lifestyle changes offer some benefits, medical interventions are essential to manage this condition effectively. Statins, the primary medications used to lower LDL cholesterol, have limitations, including the unintended upregulation of proprotein convertase subtilisin/kexin type 9 (PCSK9). Therefore, exploring alternative approaches to enhance LDL receptor expression while targeting PCSK9 is crucial, with herbal medicine showing promise in this endeavor.
Objective: This study investigates the potential of pomegranate peel extract and punicalagin, a key pomegranate component, in lowering LDL cholesterol in HepG2 cells. The research explores their effects on LDL receptor (LDLR) expression, LDL uptake, and proprotein convertase subtilisin/kexin type 9 (PCSK9) gene expression.
Methods: HepG2 cells were treated with different concentrations of pomegranate peel extract (37.5, 75, 150, and 300 μg/ml) and punicalagin (12.5, 25, 50, and 100 μg/ml). Next, the viability of HepG2 cells, the protein levels of LDL receptors and LDL uptake, and the expression levels of PCSK9 were measured.
Results: Pomegranate peel extract (37.5, 75, 150, and 300 μg/ml) and punicalagin (12.5, 25, 50, and 100 μg/ml) did not exhibit significant cytotoxicity and significantly increased LDLR protein levels (P-value= 0.00, after 24 hours) and LDL cholesterol uptake (P-value= 0.00, after 24 hours). Furthermore, they exhibited a dose-dependent reduction in the expression of PCSK9 (pomegranate: P-value= 0.01; punicalagin: P-value= 0.00).
Conclusion: These findings suggest that pomegranate peel extract and punicalagin have the potential to serve as effective agents in managing hypercholesterolemia by enhancing LDL receptor expression and reducing PCSK9 expression in HepG2 cells. Further research is required to explore their effects on transcription factors and PCSK9 function.
Keywords: Pomegranate; Punicalagin; HepG2 cell; LDL; Cardiovascular; Punica granatum
Effects of Blood Flow Restriction Resistance Training on Autonomic and Endothelial Function in Persons with Parkinson’s Disease
Authors: Bane Annie , Wilson Lorraine , Jumper Jill , Spindler Lindsay , Wyatt Pricilla , Willoughby Darryn 
Published: April 2024

Background: Autonomic dysfunction precedes endothelial dysfunction in Parkinson’s disease (PD) and causes blood pressure and circulation abnormalities that are highly disruptive to one’s quality of life. While exercise interventions have proven helpful for motor symptoms of PD, improving associated non-motor symptoms is limited. Low-intensity resistance training with blood flow restriction (LIRT-BFR) improves autonomic dysfunction in non-PD patients and high-intensity resistance training (HIRT) is recommended for motor symptom improvements for people with PD (PwPD). Objective: To determine the effects of LIRT-BFR and HIRT on homocysteine and autonomic and endothelial function in PwPD and to determine the hemodynamic loads during LIRT-BFR and HIRT in PwPD using a novel exercise protocol. Methods: Thirty-eight PwPD were assigned LIRT-BFR, HIRT or to a control (CNTRL) group. The LIRT-BFR and HIRT groups exercised three days per week for four weeks. The LIRT-BFR protocol used 60% limb occlusion pressure (LOP) and performed three sets of 20 repetitions at 20% of the one-repetition maximum (1RM). The HIRT group performed three sets of eight repetitions at 80% 1RM. The CNTRL group was asked to continue their normal daily routines. Results: LIRT-BFR significantly improved orthostatic hypotension ( p = 0.026), homocysteine levels ( p < 0.001), peripheral circulation ( p = 0.003), supine blood pressure ( p = 0.028) and heart rate variability ( p = 0.041); LIRT-BFR improved homocysteine levels ( p < 0.018), peripheral circulation ( p = 0.005), supine blood pressure ( p = 0.007) and heart rate variability ( p = 0.047) more than HIRT; and hemodynamic loads for LIRT-BFR and HIRT were similar. Conclusions: LIRT-BFR may be more effective than HIRT for autonomic and endothelial function improvements in PwPD and hemodynamic loads may be lessened in LIRT-BFR protocols using single-joint exercises with intermittent blood flow restriction. Further research is needed to determine if non-motor symptoms improve over time and if results are sustainable.
Oscillation-Specific Nodal Differences in Parkinson’s Disease Patients with Anxiety
Authors: Chang Bowen , Mei Jiaming , Ni Chen , Chen Peng , Jiang Yuge , Niu Chaoshi 
Published: April 2024

Background: Parkinson’s disease (PD) is a common neurodegenerative disorder that is predominantly known for its motor symptoms but is also accompanied by non-motor symptoms, including anxiety. Objective: The underlying neurobiological substrates and brain network changes associated with comorbid anxiety in PD require further exploration. Methods: An analysis of oscillation-specific nodal properties in patients with and without anxiety was conducted using resting-state functional magnetic resonance imaging (rs-fMRI) and graph theory. We used a band-pass filtering approach to differentiate oscillatory frequency bands for subsequent functional connectivity (FC) and graph analyses. Results: The study included 68 non-anxiety PD (naPD) patients, 62 anxiety PD (aPD) patients, and 64 healthy controls (NC). Analyses of nodal betweenness centrality (BC), degree centrality (DC), and efficiency were conducted across multiple frequency bands. The findings indicated no significant differences in BC among naPD, aPD, and NC within the 0.01–0.08 Hz frequency range. However, we observed a specific reduction in BC at narrower frequency ranges in aPD patients, as well as differing patterns of change in DC and efficiency, which are believed to reflect the neurophysiological bases of anxiety symptoms in PD. Conclusions: Differential oscillation-specific nodal characteristics have been identified in PD patients with anxiety, suggesting potential dysregulations in brain network dynamics. These findings emphasize the complexity of brain network alterations in anxiety-associated PD and identify oscillatory frequencies as potential biomarkers. The study highlights the importance of considering oscillatory frequency bands in the analysis of brain network changes.
KESIAPAN GURU PENDIDIKAN AGAMA ISLAM DALAM MENGHADAPI KURIKULUM MERDEKA DI MTS AL ISHLAH PAGERUYUNG KABUPATEN KENDAL
Authors: Nurfitriani Oriza , Aziz , Noor , Amin Nugroho M. Yusuf 
Published: April 2024

Saat ini Indonesia sedang menggalakkan sebuah kurikulum baru yang bernama Kurikulum Merdeka, hal ini menuntut semua lembaga pendidikan untuk mempersiapkan diri dalam menghadapi kurikulum tersebut, termasuk di MTs Al Ishlah Pageruyung Kabupaten Kendal.
Penelitian ini bertujuan untuk: 1) Mengetahui konsep kurikulum merdeka pada tingkat Sekolah Menengah Pertama/MTs; 2) Mengetahui kesiapan guru pendidikan agama Islam dalam menghadapi kurikulum merdeka di MTs Al Ishlah Pageruyung Kabupaten Kendal; 3) Mengetahui faktor pendukung dan penghambat guru pendidikan agama Islam dalam menghadapi kurikulum merdeka di MTs Al Ishlah Pageruyung Kabupaten Kendal.
Penelitian ini menggunakan pendekatan penelitian kualitatif dimana jenis penelitiannya bersifat deskriptif. Teknik pengumpulan data menggunakan metode observasi, wawancara, dan dokumentasi. Kemudian sumber data diperoleh dari sumber data primer dan data sekunder (observasi, wawancara, dan dokumentasi yang berkaitan dengan kurikulum merdeka). Adapun teknik analisis yang digunakan adalah teknik reduksi data, penyajian data, dan verifikasi data.
Hasil penelitian menunjukkan bahwa: 1) Konsep kurikulum merdeka pada tingkat satuan pendidikan SMP/MTs berbeda dengan tingkat satuan pendidikan lainnya. 2) Kesiapan guru pendidikan agama Islam dalam menghadapi kurikulum merdeka di MTs Al Ishlah Pageruyung kabupaten Kendal sudah dimulai dengan sosialisasi awal, memodifikasi RPP dengan penambahan Profil Pelajar Pancasila, penganggaran biaya sekolah, pengadaan laboratorium komputer, serta peningkatan SDM. Namun bila dibandingkan dengan teori yang ada, kesiapan tersebut masih kurang. Seperti perlunya peningkatan infrastruktur, sarana dan prasarana, sosialisasi dan pelatihan kurikulum merdeka dan penggalakan platform merdeka mengajar. 3) Faktor pendukung guru PAI dalam menghadapi kurikulum merdeka di MTs Al Ishlah: adanya bimbingan dari pengawas madrasah, guru sudah bisa menggunakan media digital dan mengajar sesuai keahlian, adanya laboratorium komputer. Faktor penghambat guru PAI dalam menghadapi kurikulum merdeka di MTs Al Ishlah: sosialisasi kurang, media digital belum memadahi, peningkatan kualitas guru PAI masih terhambat, infrastruktur sekolah rendah.
Immunohistochemical Characterization of Breast Carcinoma: Clinical Correlations, Molecular Subtypes, and Therapeutic Implications
Authors: Barodawala Shaikhali , Lila Kunjal , Chadha Kirti , Pradhan Gauri , Parab Pooja , Jatale Raj , Ramchandran Shibani 
Published: April 2024

Background: Breast carcinoma exhibits heterogeneity in terms of morphology, molecular, treatment response, and clinical outcomes. The objective of the study was to classify the various malignant breast cancer cases based on their immunohistochemical characteristics and understand their association and behavior, which may be useful for predicting treatment and prognosis.
Methods: In this study, 12808 malignant breast cancer cases were studied based on hormone receptor IHC biomarkers, age, gender, histological type, grade and molecular classifiers.
Results: The mean age of patients was 53.63+13.08 years, around 45.43% were grade 3 tumors and the invasive duct carcinoma of non-specified type (NST) was the most common type seen (93.83%). ER positivity was 83.89% in grade 1, 69.9% in grade 2, and 36.86% in grade 3 tumors, and the overall PR and Her-2 positivity was 47.06% and 18.67%, respectively. A relatively higher percentage of Triple Negative cases was seen (36.58%), followed by 25.43% Luminal A cases. There was a significant association between molecular subtypes with respect to age, gender, Scarff Bloom Richardson (SBR) grade, and histological type (P<0.0001). Overall, grade 3 tumor cases were most common, the majority of which were Triple Negative. Maximum cases of triple negative tumors were seen among women, being mostly concentrated in younger age group i.e. <40 years.
Conclusion: Immunohistochemistry for hormone receptor positivity remains the mainstay of diagnosis and molecular sub-classification. The hormone response of tumors is important prognostically, in predicting the treatment outcomes. Going further, molecular analysis and gene expression studies can further augment the histopathological diagnosis to assist strategies of targeted therapy and precision medicine resulting in better patient outcomes.
Root Map
Authors: Purvis Rosalie 
Published: April 2024

The year 2015 began with the greatest number of displaced people across the globe since the Second World War. More than ever, those of us who have lacked the luxury of a place to call “home” yearn for stories and performances that connect us across conflicted borders. In response to this global crisis, I joined forces with Kolkata based Arts Collective Chaepani, whose work centers around topics of migration and crossing cultural barriers. Via Praxis as Research (PAR), Root Map: Embracing the Border as Method argues that, in order to connect people across cultural and national borders, we must embrace performative realities that emerge from the rhythms of migration, diaspora and border spaces.
Effect Of Use Of Aromatherapy And Murotal Therapy In Mother's Parting With Anxiety
Authors: Maya Herlina Siskha , Ulya Yadul , Yunika Regina Pricilia 
Published: April 2024

Background: Anxiety is a feeling of fear that is unclear and not supported by the situation. Individuals who feel anxious will feel uncomfortable or afraid, but do not know the reason why this condition occurs. Anxiety has no clear, identifiable stimulus. Murotal therapy can speed up healing and reduce anxiety, listening to the holy verses of the Al-qur’an has a significant influence in reducing tension in the reflective nerves. The recommended aroma for mediating anxiety is aromatherapy based on lemon essential oil (Citrus limon) Objective: To determine the effectiveness of Murottal therapy on the level of anxiety of women giving birthMethod: This type of research uses qualitative research, with a cross-sectional approach. The sample in this study was 30 mothers in the first stage of labor. This research uses chi square data analysisResults: Based on the frequency distribution of the influence of the use of aromatherapy and murrotal therapy on mothers giving birth with anxiety, it shows that there is an influence of the use of aromatherapy and murrotal therapy on mothers giving birth with anxiety.Conclusion: Based on the research results, murottal therapy on maternal anxiety levels before giving birth is effective.Suggestion: Murottal therapy has good effectiveness, it is hoped that this therapy can relieve and be a solution to the anxiety experienced by mothers during pregnancy, childbirth and postpartum. Keywords: Anxiety, Murottal Al-Qur'an, Aromateraphy
تاثير برنامج ترويحي بمصاحبة الموسيقى على بعض المتغيرات الوظيفية لدى أطفال ذوي متلازمة داون
Authors: Nivian Yasser Abdullah  , Assis  prof.Dr.  Bajar Ali Gokal  
Published: April 2024

الملخص
هدف البحث التعرف على:-

تأثير البرنامج الترويحي الترويحي والبرنامج المتبع في المتغيرات الوظيفية المحددة في البحث .

أعتمد الباحثان على المنهج التجريبي وفق التصميم التجريبي الذي يعرف بتصميم المجموعتين المتكافئتين ذات الاختبار القبلي والبعدي، وتم تحديد عينة البحث من ذوي متلازمة داون بأعمار(9-14) سنة وبواقع(20) طفلا ومن الذكور فقط، وتم توزيعهم عشوائيا الى مجموعتين ضابطة وتجريبية وبواقع (10) أطفال لكل مجموعة.وتحددت ادوات البحث ببعض المتغيرات الفسيولوجية ، واجرى الباحثان التكافؤ والتجانس لمتغيرات الدراسة، وبعد الانتهاء من تنفيذ البرنامج الترويحي تم اجراء الاختبارات البعدية ومعالجة البيانات بالوسائل الاحصائية المناسبة ، وتوصلت الدراسة الى مجموعة من الاستنتاجات اهمها:-
1- فاعلية البرنامج الترويحي المصاحب بالموسيقى في المتغيرات الوظيفية
2-تفوق البرنامج الترويحي المصاحب بالموسيقى على البرنامج المتبع في التأثير على المتغيرات الوظيفية
Outcome of Surgery in Ruptured Aneurysm: A Study of 48 Cases
Authors: Haradhan Deb Nath  , Razib KH Olinur , Rathin Halder  , Md Ataur Rahman  , Md Motasimul Hasan  , Abu Naim Wakil Uddin  , Md Rabiul Karim  , Sudip Barua  , SK Farhad Munir  , Barua Kanak Kanti 
Published: April 2024

Background : Rupture aneurysm is a dangerous clinical condition of a patient. The aim of this study is to find out the outcome of rupture aneurysm after microsurgical clipping.
Method: This was a prospective cross sectional study and was conducted at the department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from January 2011 to April 2022.
Results : Among 48 patient 30(62.5%) were male. It was documented that 32(66.6%) patients were belong to 51-60 years. It was evident that the most of the clinical presentation was history of sudden severe headache 48(100%), 32(66.6%) patients had presented with vomiting and brief loss of consciousness had 24(50%). The highest percentage of WFNS grading of during admission were (1-3), 32(66.6%). Peroperative rupture during surgery were 16(33.33%). During discharge good recovery was occurred 38(79.7%) and 5(10.5%) had death.
Conclusion: We have treated all the case by microsurgical clipping. Still microsurgical clipping is one of the gold standard procedure for rupture intracerebral aneurysm.
Bang. J Neurosurgery 2023; 12(2): 114-121