bluuebunny/crossref_metadata_2025_split huggingface dataset:
Failure of drug eluting stents presented as definite stent thrombosis
Authors: Vaknin‐Assa Hana , Assali Abid , Lev Eli I. , Ukabi Shimrit , Tamir Bental , Kornowski Ran 
Published: December 2009

AbstractBackground: Stent thrombosis (ST) risk may persist long after a successful drug eluting stents (DES) implantation. Objective:We evaluated the incidence, timing, and clinical outcomes of patients with early (≤30 days), late (>30–365 days), and very late (>365 days) angiographically proven ST related to DES. Methods: Between 2004 and 2009, 4,396 patients underwent percutaneous coronary interventions (PCI) with DES implantations. This 5‐year follow‐up study included 38 patients (mean age 60 ± 12 years; 76% males) who were readmitted with confirmed ST diagnoses. Clopidogrel therapy was prescribed for 3–12 months. Clinical follow‐ups were conducted at 1 and 6 months following ST events. Results:The overall ST rate was 0.9% (38/4,396); the late ST rate was 0.7%. There were four (11%) early and 34 (89%) late events; the time interval to thrombosis was 21 ± 14 months (range 0.13–60 months). Two patients had stent fractures associated with ST, 37% had diabetes, and 68% presented with ST‐elevation myocardial infarctions (MI). One third was treated with clopidogrel at the ST event. Three patients (8%) had recurrent late ST events and two died within 1 month after the ST event (5%). At 6 months, we observed a 26% major adverse cardiac event rate, and the overall cardiac mortality rate was 8%. Conclusions: In our series, ST occurred infrequently (0.9%), mostly between 1 and 3 years after the period recommended for dual anti‐platelet pharmacotherapy, and it is associated with substantial clinical consequences. © 2010 Wiley‐Liss, Inc.
Transradial complex left main trifurcation intervention
Authors: Hussein Hesham , Fang Hsiu‐Yu , Wu Chiung‐Jen 
Published: December 2009

AbstractTrifurcation lesions, especially around the left main coronary artery (LMCA), are occasionally encountered. Complex lesions, involving the bifurcation or the trifurcation of the unprotected LMCA, represent a real challenge for interventional cardiologists. Trifurcation lesions intervention reported to have high overall major adverse cardiovascular events, and require the use of various complex interventional techniques, for example, large guiding catheters to accommodate three wires guiding simultaneously inflated balloons or stents. Here, we report a case of successful percutaneous coronary intervention supported by pre‐and post‐intravascular ultrasound imaging, on an LMCA trifurcation using a 6F guiding catheter via transradial approach. © 2010 Wiley‐Liss, Inc.
Selective use of embolic protection devices during saphenous vein grafts interventions: A single‐center experience
Authors: Lavi Shahar , Ivanov Joan , Appleby Clare E. , Seidelin Peter H. , Mackie Karen , Schwartz Leonard , Džavík Vladimír 
Published: December 2009

AbstractObjectives: To report on outcomes with selective use of embolic protection devices (EPD) during percutaneous coronary intervention (PCI) to saphenous vein grafts (SVG). Background: PCI to SVG is associated with increased risk and the use of EPD is recommended in this setting. Methods: Angiographic and clinical outcomes were prospectively obtained from 534 consecutive patients who underwent PCI to SVG with or without EPD at a tertiary cardiac centre. Long‐term outcomes were obtained by linkage to a provincial registry. Results: EPD, deployed in 198 of 373 SVGs (53%) suitable for deployment of a distal EPD, were used more often in ectatic (33% vs. 19%, P = 0.003), ulcerated (17% vs. 9%, P = 0.03), thrombotic (26% vs. 10%, P < 0.0001) vein grafts, with longer degenerated segments (P = 0.002), and in lesions involving the body of the graft (85% vs. 66%, P < 0.0001), and less with lesions involving the graft ostium (29% vs. 44%, P = 0.003). Patients suitable for but not receiving EPD tended to be more likely to have a periprocedural myocardial infarction. During 3 years of follow‐up, 49% of the patients had a cardiovascular event. Cumulative mortality was 8.4%, 18.8% and 14.7% in patients unsuitable for distal EPD, suitable but without EPD, and with EPD (p = 0.11). Nonuse of EPD was an independent predictor of MACE at 3 years. (P = 0.02). Conclusions: Selective use of EPD is associated with low in‐hospital cardiovascular event rates. Long‐term outcomes are manifested by a high rate of events, especially in patients with SVG's suitable for but not receiving EPD. This suggests that routine use of distal EPD may be warranted in unselected patients with suitable SVG anatomy. © 2010 Wiley‐Liss, Inc.
Endovascular treatment of Angio‐Seal™‐related limb ischemia—Primary results and long‐term follow‐up
Authors: Thalhammer Christoph , Joerg Gian R. , Roffi Marco , Husmann Marc , Pfammatter Thomas , Amann‐Vesti Beatrice R. 
Published: December 2009

AbstractObjectives: To investigate primary success rates and long term follow‐up of endovascular treatment of AngioSeal™‐related limb ischemia. Background: Current knowledge on optimal therapy of ischemic complications following application of AngioSeal™ is limited. Methods: A single‐center prospectively maintained database was retrospectively interrogated and AngioSeal™—related complications requiring endovascular treatment over an 8‐year‐time period was identified. Results: Fifteen patients fulfilling the inclusion criteria were identified, resulting in an approximated incidence of 0.26% of all devices implanted at our institution. In all cases, the complication was managed successfully in the absence of complications. Eleven patients were treated with balloon angioplasty (PTA) and four with stent implantation because of suboptimal PTA results. Twelve patients were available for noninvasive vascular follow‐up examination for a median time of 40 months postinterventionally. Only two patients needed a second intervention consisting of balloon angioplasty due to symptomatic restenosis. At final follow‐up all patients were asymptomatic with no relevant restenosis. Conclusion: Endovascular treatment for AngioSeal™‐related limb ischemia with or without stent implantation results in an excellent immediate and long‐term clinical and hemodynamic outcome. © 2009 Wiley‐Liss, Inc.
Enhancing the Orienting Properties of Poly(γ‐benzyl‐L‐glutamate) by means of Additives
Authors: Marx Andreas , Böttcher Benjamin , Thiele Christina M. 
Published: December 2009

AbstractResidual dipolar couplings (RDCs) have recently become increasingly important in organic structure determination due to their unique information content. One main limitation for the use of RDCs in organic compounds is the orientation that needs to be induced to be able to measure RDCs. So far, there are very few possibilities to modulate the orientational properties of organic solutes and even less when chiral media are considered. Based on our recent findings that the critical concentration of the liquid‐crystalline phase of homopolypeptides depends on their molecular weight, we sought for further ways to modulate the orienting properties. We were especially interested in seeing whether we could not only influence the induced degree of orientation, but whether we could also change the solute′s preferred orientation and even enhance enantiodifferentiation. We thus tried different aprotic and protic additives and were successful in all of the above‐mentioned aspects by using CCl4 as the additive. Furthermore, we consider DMSO to be a very useful additive. The LC phase of low MW poly(γ‐benzyl‐L‐glutamate) (PBLG) is usually unstable when DMSO is added. The high MW PBLG used in this study, however, remained stable up to a DMSO/CDCl3 ratio of 1:2. By using this combination of solvents, the alignment of the two enantiomers of a compound, which is insoluble in CDCl3, namely, the HCl salt of a tryptophane ester, was possible leading to high‐quality spectra. The two enantiomers of the tryptophane ester showed different couplings, thus indicating that enantiodifferentiation is taking place. Thus we were able to modulate the orienting properties (degree of orientation, preferred orientation and enantiodifferentiation) of PBLG by using additives and to increase the accessible solvent and solute range significantly.
A Highly Versatile Catalyst System for the Cross‐Coupling of Aryl Chlorides and Amines
Authors: Lundgren Rylan J. , Sappong‐Kumankumah Antonia , Stradiotto Mark 
Published: December 2009

AbstractThe syntheses of 2‐(di‐tert‐butylphosphino)‐N,N‐dimethylaniline (L1, 71 %) and 2‐(di‐1‐adamantylphosphino)‐N,N‐dimethylaniline (L2, 74 %), and their application in Buchwald–Hartwig amination, are reported. In combination with [Pd(allyl)Cl]2 or [Pd(cinnamyl)Cl]2, these structurally simple and air‐stable P,N ligands enable the cross‐coupling of aryl and heteroaryl chlorides, including those bearing as substituents enolizable ketones, ethers, esters, carboxylic acids, phenols, alcohols, olefins, amides, and halogens, to a diverse range of amine and related substrates that includes primary alkyl‐ and arylamines, cyclic and acyclic secondary amines, NH imines, hydrazones, lithium amide, and ammonia. In many cases, the reactions can be performed at low catalyst loadings (0.5–0.02 mol % Pd) with excellent functional group tolerance and chemoselectivity. Examples of cross‐coupling reactions involving 1,4‐bromochlorobenzene and iodobenzene are also reported. Under similar conditions, inferior catalytic performance was achieved when using Pd(OAc)2, PdCl2, [PdCl2(cod)] (cod=1,5‐cyclooctadiene), [PdCl2(MeCN)2], or [Pd2(dba)3] (dba=dibenzylideneacetone) in combination with L1 or L2, or by use of [Pd(allyl)Cl]2 or [Pd(cinnamyl)Cl]2 with variants of L1 and L2 bearing less basic or less sterically demanding substituents on phosphorus or lacking an ortho‐dimethylamino fragment. Given current limitations associated with established ligand classes with regard to maintaining high activity across the diverse possible range of CN coupling applications, L1 and L2 represent unusually versatile ligand systems for the cross‐coupling of aryl chlorides and amines.
Intermediates Involved in the Oxidation of Nitrogen Monoxide: Photochemistry of the cis‐N2O2⋅O2 complex and of sym‐N2O4 in Solid Ne Matrices
Authors: Beckers Helmut , Zeng Xiaoqing , Willner Helge 
Published: December 2009

AbstractPure sym‐N2O4 isolated in solid Ne was obtained by passing cold neon gas over solid N2O4 at −115 °C and quenching the resulting gaseous mixture at 6.3 K. Filtered UV irradiation (260–400 nm) converts sym‐N2O4 into trans‐ONONO2, a weakly interacting (NO2)2 radical pair, and traces of the cis‐N2O2⋅O2 complex. Besides the weakly bound ON⋅O2 complex, cis‐N2O2⋅O2 was also obtained by co‐deposition of NO and O2 in solid Ne at 6.3 K, and both complexes were characterised by their matrix IR spectra. Concomitantly formed cis‐N2O2 dissociated on exposure to filtered IR irradiation (400–8000 cm−1), and the cis‐N2O2⋅O2 complex rearranged to sym‐N2O4 and trans‐ONONO2. Experiments using 18O2 in place of 16O2 revealed a non‐concerted conversion of cis‐N2O2⋅O2 into these species, and gave access to four selectively di‐18O‐substituted trans‐ONONO2 isotopomers. No isotopic scrambling occurred. The IR spectra of sym‐N2O4 and of trans‐ONONO2 in solid Ne were recorded. IR fundamentals of trans‐ONONO2 were assigned based on experimental 16/18O isotopic shifts and guided by DFT calculations. Previously reported contradictory measurements on cis‐ and trans‐ONONO2 are discussed. Dinitroso peroxide, ONOONO, a proposed intermediate in the IR photoinduced rearrangement of cis‐N2O2⋅O2 to the various N2O4 species, was not detected. Its absence in the photolysis products indicates a low barrier (≤10 kJ mol−1) for its exothermic OO bond homolysis into a (NO2)2 radical pair.
Ring‐Opening/Ring‐Closing Protocols from Nitrothiophenes: Six‐Membered versus Unusual Eight‐Membered Sulfur Heterocycles through Michael‐Type Addition on Nitrobutadienes
Authors: Bianchi Lara , Giorgi Gianluca , Maccagno Massimo , Petrillo Giovanni , Sancassan Fernando , Severi Elda , Spinelli Domenico , Stenta Marco , Tavani Cinzia 
Published: December 2009

AbstractWhen Ar is a low‐aromaticity homo‐ or heterosystem, the sulfonyl‐stabilized anion of nitrobutadienes 4 (which derive from the initial ring opening of 3‐nitrothiophene) undergoes a rather surprising addition onto the aromatic ring itself, thereby leading to the construction of an unusual eight‐membered sulfur heterocycle condensed with the original Ar ring. The competitiveness of such a pathway with respect to the formation of the thiopyran ring (i.e., addition onto the nitrovinyl moiety) is favored at low temperatures, thus revealing its nature as a kinetically controlled process.
A Smart Glycol‐Directed Nanodevice from Rationally Designed Macroporous Materials
Authors: Qian Kun , Wan Jingjing , Huang Xiaodan , Yang Pengyuan , Liu Baohong , Yu Chengzhong 
Published: December 2009

AbstractWe have developed a smart nanodevice for the highly efficient and selective detection of glycoproteins. This polyfunctional device is fabricated through the rational functionalization of macroporous silica foam (MOSF) materials with a boron species (B‐MOSF) and amino groups (NH2‐MOSF), and then the integration of MOSF, B‐MOSF and NH2‐MOSF materials. In such a device, a macroporous structure with very large‐pore sizes (diameters≈100 nm) and high‐pore volumes (>0.65 cm3 g−1) is advantageous to efficiently fasten the enzymatic reaction. The targeted specific glycopeptides of the products can be selectively isolated and enriched in B‐MOSF through the chemo‐affinity between boronic acid and glycol groups, while the non‐specific peptides are released to the solutions, or further purified by MOSF and NH2‐MOSF, which have opposite charges. As a result, the protein digestion and glycol‐peptide isolation can be simultaneously achieved in the functionalized macroporous materials in one step, which is a great advantage compared to conventional multi‐procedure and time‐consuming techniques.
Reversible Dimerization of EGFR Revealed by Single‐Molecule Fluorescence Imaging Using Quantum Dots
Authors: Kawashima Nagako , Nakayama Kenichi , Itoh Kohji , Itoh Tamitake , Ishikawa Mitsuru , Biju Vasudevanpillai 
Published: December 2009

AbstractThe current work explores intermolecular interactions involved in the lateral propagation of cell‐signaling by epidermal growth factor receptors (EGFRs). Activation of EGFRs by binding an EGF ligand in the extracellular domain of the EGFR and subsequent dimerization of the EGFR initiates cell‐signaling. We investigated interactions between EGFRs in living cells by using single‐molecule microscopy, Förster resonance energy transfer (FRET), and atomic force microscopy. By analyzing time‐correlated intensity and propagation trajectories of quantum dot (QD)‐labeled EGFR single molecules, we found that signaling dimers of EGFR [(EGF‐EGFR)2] are continuously formed in cell membrane through reversible association of heterodimers [EGF(EGFR)2]. Also, we found that the lateral propagation of EGFR activation takes place through transient association of a heterodimer with predimers [(EGFR)2]. We varified the transient association between activated EGFR and predimers using FRET from QD‐labeled heterodimers to Cy5‐labeled predimers and correlated topography and fluorescence imaging. Without extended single‐molecule fluorescence imaging and by using bio‐conjugated QDs, reversible receptor dimerization in the lateral activation of EGFR remained obscured.
ChemInform Abstract: CaAgxZn1‐x: Between CrB and FeB Structure Type — A Study on Electronic Factors Influencing Stacking of Zig‐Zag Chains in Polar Alkaline Earth Monometallides.
Authors: Harms Wiebke , Mihajlov Viktoria , Wendorff Marco , Roehr Caroline 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Phase Transitions in the Relaxor Ferroelectric Pb2Bi4Ti5O18.
Authors: Goff Richard J. , Lightfoot Philip 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Crystal Structures and High‐Temperature Phase Transitions of the New Ordered Double Perovskites Sr2SmSbO6 and Sr2LaSbO6.
Authors: Faik A. , Iturbe‐Zabalo E. , Urcelay I. , Igartua J. M. 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetism and Negative Magnetoresistance of Two Magnetically Ordering, Rare‐Earth‐Containing Zintl Phases with a New Structure Type: EuGa2Pn2 (Pn: P, As).
Authors: Goforth Andreas M. , Hope Haakon , Condron Cathie L. , Kauzlarich Susan M. , Jensen Newell , Klavins Peter , MaQuilon Samuel , Fisk Zachary 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of [XeF5]3[Ti4F19] Containing a Discrete [Ti4F19]3‐ Anion.
Authors: Mazej Zoran , Goreshnik Evgeny 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unique LaTaO4 Polymorph for Multiple Energy Applications.
Authors: Nyman May , Rodriguez Mark A. , Rohwer Lauren E. S. , Martin James E. , Waller Mollie , Osterloh Frank E. 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cs2K(UO)2Si4O12: A Mixed‐Valence Uranium(IV,V) Silicate.
Authors: Lee Cheng‐Shiuan , Wang Sue‐Lein , Lii Kwang‐Hwa 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a Nitrogen‐Stabilized Hexagonal Re3ZnNx Phase Using High Pressures and Temperatures.
Authors: Serghiou George , Guillaume Christophe L. , Thomson Andrew , Morniroli Jean‐Paul , Frost Dan J. 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nickel‐Deficient Stannides Eu2Ni2‐xSn5 — Structure, Magnetic Properties, and Moessbauer Spectroscopic Characterization.
Authors: Harmening Thomas , Eul Matthias , Poettgen Rainer 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: TTMPP: An Efficient Organocatalyst in the Ring‐Opening of Aziridines with Silylated Nucleophiles.
Authors: Matsukawa Satoru , Tsukamoto Kumiko 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Simple and Efficient Oxidation of Alcohols with Ruthenium on Carbon.
Authors: Mori Shigeki , Takubo Masato , Makida Kazuya , Yanase Takayoshi , Aoyagi Satoka , Maegawa Tomohiro , Monguchi Yasunari , Sajiki Hironao 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Aromatic C—H Halogenation with Hydrogen Halides by Means of Electrochemical Oxidation.
Authors: Kakiuchi Fumitoshi , Kochi Takuya , Mutsutani Hitoshi , Kobayashi Noboru , Urano Seiya , Sato Mitsuo , Nishiyama Shigeru , Tanabe Takamasa 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fe‐Catalyzed Oxidative Coupling of Heteroarenes and Methylamines.
Authors: Ohta Masaki , Quick Matthias P. , Yamaguchi Junichiro , Wuensch Bernhard , Itami Kenichiro 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral 2‐Aminobenzimidazoles as Recoverable Organocatalysts for the Addition of 1,3‐Dicarbonyl Compounds to Nitroalkenes.
Authors: Almasi Diana , Alonso Diego A. , Gomez‐Bengoa Enrique , Najera Carmen 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Beyond the Aza‐Morita—Baylis—Hillman Reaction: Lewis Base Catalyzed Reactions of N‐Boc‐imines with Ethyl 2,3‐Butadienoate.
Authors: Guan Xiao‐Yang , Wei Yin , Shi Min 
Published: December 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.