bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using impact assessment study designs for addressing impacts to species of conservation concern
Authors: Marshall Mike E. , Long Ashley M. , Farrell Shannon L. , Mathewson Heather A. , Morrison Michael L. , Newnam Cal , Wilkins R. Neal 
Published: August 2012

AbstractImpact assessments are a valuable tool for investigating the effects of human‐induced and natural perturbations on ecosystems and wildlife, including species of conservation concern. The breeding range of the golden‐cheeked warbler (Setophaga chrysoparia), a federally endangered species, is located in a region with increasing development that includes housing, road construction and maintenance, and other land‐use conversions; along with wildfire, oak wilt, and other disturbances. Although many of these actions are assumed to have deleterious effects on warbler occurrence or fitness, there is limited research directly investigating impacts of these activities to date. Many of these threats cannot be investigated within a fully manipulative study framework because it is rarely possible or even appropriate to replicate treatments. We conducted impact assessment studies investigating the effects of military training and highway construction on the warbler. We use these studies to provide examples that demonstrate how common challenges in investigating impacts can be addressed during planning and implementation by using alternative study design and sampling strategies to effectively assess the impact of perturbations on species of interest. © 2012 The Wildlife Society.
Zr2N2Se: The First Zirconium(IV) Nitride Selenide by the Oxidation of Zirconium(III) Nitride with Selenium
Authors: Lissner Falk , Hack Bettina , Lerch Martin , Schleid Thomas 
Published: August 2012

AbstractThe oxidation of zirconium(III) nitride (ZrN) with suitable amounts of selenium (Se) in the presence of sodium chloride (NaCl) as flux yields small yellow brownish platelets of the first zirconium(IV) nitride selenide with the composition Zr2N2Se. The new compound crystallizes in the hexagonal space group P63/mmc (no. 194) with a = 363.98(2) pm, c = 1316.41(9) pm (c/a = 3.617) and two formula units per unit cell. The crystallographically unique Zr4+ cations are surrounded by three selenide and four nitride anions in the shape of a capped trigonal antiprism. The Se2– anions are coordinated by six Zr4+ cations as trigonal prism and the N3– anions reside in tetrahedral surrounding of Zr4+ cations. These [NZr4]13+ tetrahedra become interconnected via three edges each to form $\rm^{2}_{\infty}${[(NZr4/4)2]2+} double layers parallel to the (001) plane, which are held together by monolayers of Se2– anions.
Return of Genetic Results in the Familial Dilated Cardiomyopathy Research Project
Authors: Siegfried Jill D. , Morales Ana , Kushner Jessica D. , Burkett Emily , Cowan Jason , Mauro Ana Clara , Huggins Gordon S. , Li Duanxiang , Norton Nadine , Hershberger Ray E. 
Published: August 2012

AbstractThe goal of the Familial Dilated Cardiomyopathy (FDC) Research Project, initiated in 1993, has been to identify and characterize FDC genetic cause. All participating individuals have been consented for the return of genetic results, an important but challenging undertaking. Since the inception of the Project we have enrolled 606 probands, and 269 of these had 1670 family members also enrolled. Each subject was evaluated for idiopathic dilated cardiomyopathy (IDC) and pedigrees were categorized as familial or sporadic. The coding regions of 14 genes were resequenced in 311 to 324 probands in five studies. Ninety‐two probands were found to carry nonsynonymous rare variants absent in controls, and with Clinical Laboratory Improvement Amendment of 1988 (CLIA) compliant protocols, relevant genetic results were returned to these probands and their consented relatives by study genetic counselors and physicians in 353 letters. In 10 of the 51 families that received results >1 year ago, at least 23 individuals underwent CLIA confirmation testing for their family's rare variant. Return of genetic results has been successfully undertaken in the FDC Research Project. This report describes the methods utilized in the process of returning research results. We use this information as a springboard for providing guidance to other genetic research groups and proposing future directions in this arena.
Diverging Destinies: Maternal Education and the Developmental Gradient in Time With Children
Authors: Kalil Ariel , Ryan Rebecca , Corey Michael 
Published: August 2012

Abstract
Using data from the 2003–2007 American Time Use Surveys (ATUS), we compare mothers’ (N = 6,640) time spent in four parenting activities across maternal education and child age subgroups. We test the hypothesis that highly educated mothers not only spend more time in active child care than less-educated mothers but also alter the composition of that time to suit children’s developmental needs more than less-educated mothers. Results support this hypothesis: not only do highly educated mothers invest more time in basic care and play when youngest children are infants or toddlers than when children are older, but differences across education groups in basic care and play time are largest among mothers with infants or toddlers; by contrast, highly educated mothers invest more time in management activities when children are 6 to 13 years old than when children are younger, and differences across education groups in management are largest among mothers with school-aged children. These patterns indicate that the education gradient in mothers’ time with children is characterized by a “developmental gradient.”
Therapeutic Effects of Qigong in Patients with COPD: A Randomized Controlled Trial
Authors: Liu Xiao-Dan , Jin Hong-Zhu , Ng Bobby Hin-Po , Gu Yi-Huang , Wu Yun-Chuan , Lu Gan 
Published: August 2012

Objective This study was conducted to compare the therapeutic effects of health qigong (HQG) with conventional pulmonary rehabilitation (PR) exercise among patients with chronic obstructive pulmonary disease (COPD). Methods A total of 132 patients with confirmed diagnosis of COPD but no serious comorbidities were randomly allocated to the HQG group (n = 51), PR group (n = 32), or medical treatment group (n = 35). The HQG group received 1 week of HQG training under the supervision of professional coaches, and were then encouraged to participate in a peer-led weekly practice group thrice a week, lasting 1 hour each time, for 6 months. The conventional PR group received the same amount of professional coaching on breathing and aerobic exercises, and peer-led walking or ball game groups. The medical treatment group only received health education on self-exercise. Baseline data were taken before randomization, and outcomes were ascertained at the 6-month follow-up by blinded assessors. Results Overall, 118 patients with complete data were recruited into the final analysis. Irrespective of disease stages, both HQG and PR groups showed improving trends across 6-minute walk test and quality of life scores, while the medical treatment group demonstrated either no improvements or some deteriorations. When comparing HQG with PR, HQG appeared to have better effects on decreasing the frequency of exacerbation for patients with GOLD (Global Initiative for Chronic Obstructive Lung Disease) stage I and maintaining a stable tumor necrosis factor-alpha level for patients of GOLD stage II. Conclusion This study solidifies the concept that both HQG and PR produce positive effects on subjective symptoms and functions among COPD patients, and also provided evidence that HQG can induce additional effects compared to conventional PR.
Need for a global obstetric fistula training strategy
Authors: Rushwan Hamid , Khaddaj Sinan , Knight Louise , Scott Rachel 
Published: August 2012

AbstractObstetric fistula is a complication of childbirth that often follows obstructed labor and is almost exclusive to low‐resource countries. The original Global Burden of Disease Study (GBD 1990 Study) reported an incidence of 8.68 per 100 000 and a prevalence of 51.35 per 100 000 for women aged 15–44 years in low‐resource regions. The most cited global prevalence estimate is 2 million women. Although the global burden of obstetric fistula remains unclear, the number of women suffering from the condition is increasing, while surgical treatment remains limited. There are few experienced fistula surgeons and past surgical training approaches have been inconsistent. The Global Competency‐Based Fistula Surgery Training Manual developed by FIGO and partners contains a set curriculum and, to ensure its implementation, a global strategy and training program have been developed. This paper describes key elements of the training program and its implementation. The anticipated impact of the training program is a reduction in global morbidity caused by obstetric fistula.
Motion of red blood cells near microvessel walls: effects of a porous wall layer
Authors: Hariprasad Daniel S. , Secomb Timothy W. 
Published: August 2012

AbstractA two-dimensional model is used to simulate the motion and deformation of a single mammalian red blood cell (RBC) flowing close to the wall of a microvessel, taking into account the effects of a porous endothelial surface layer (ESL) lining the vessel wall. Migration of RBCs away from the wall leads to the formation of a cell-depleted layer near the wall, which has a large effect on the resistance to blood flow in microvessels. The objective is to examine the mechanical factors causing this migration, including the effects of the ESL. The vessel is represented as a straight parallel-sided channel. The RBC is represented as a set of interconnected viscoelastic elements, suspended in plasma, a Newtonian fluid. The ESL is represented as a porous medium, and plasma flow in the layer is computed using the Brinkman approximation. It is shown that an initially circular cell positioned close to the ESL in a shear flow is deformed into an asymmetric shape. This breaking of symmetry leads to migration away from the wall. With increasing hydraulic resistivity of the layer, the rate of lateral migration increases. It is concluded that mechanical interactions of RBCs flowing in microvessels with a porous wall layer may reduce the rate of lateral migration and hence reduce the width of the cell-depleted zone external to the ESL, relative to the cell-depleted zone that would be formed if the interface between the ESL and free-flowing plasma were replaced by an impermeable boundary.
Absence of singular stretching of interacting vortex filaments
Authors: Hormoz Sahand , Brenner Michael P. 
Published: August 2012

AbstractA promising mechanism for generating a finite-time singularity in the incompressible Euler equations is the stretching of vortex filaments. Here, we argue that interacting vortex filaments cannot generate a singularity by analysing the asymptotic dynamics of their collapse. We use the separation of the dynamics of the filament shape, from that of its core, to derive constraints that must be satisfied for a singular solution to remain self-consistent uniformly in time. Our only assumption is that the length scales characterizing filament shape obey scaling laws set by the dimension of circulation as the singularity is approached. The core radius necessarily evolves on a different length scale. We show that a self-similar ansatz for the filament shapes cannot induce singular stretching, due to the logarithmic prefactor in the self-interaction term for the filaments. More generally, there is an antagonistic relationship between the stretching rate of the filaments and the requirement that the radius of curvature of filament shape obeys the dimensional scaling laws. This suggests that it is unlikely that solutions in which the core radii vanish sufficiently fast to maintain the filament approximation exist.
Asymptotic analysis of the Boltzmann–BGK equation for oscillatory flows
Authors: Nassios Jason , Sader John E. 
Published: August 2012

AbstractKinetic theory provides a rigorous foundation for calculating the dynamics of gas flow at arbitrary degrees of rarefaction, with solutions of the Boltzmann equation requiring numerical methods in many cases of practical interest. Importantly, the near-continuum regime can be examined analytically using asymptotic techniques. These asymptotic analyses often assume steady flow, for which analytical slip models have been derived. Recently, developments in nanoscale fabrication have stimulated research into the study of oscillatory non-equilibrium flows, drawing into question the applicability of the steady flow assumption. In this article, we present a formal asymptotic analysis of the unsteady linearized Boltzmann–BGK equation, generalizing existing theory to the oscillatory (time-varying) case. We consider the near-continuum limit where the mean free path and oscillation frequency are small. The complete set of hydrodynamic equations and associated boundary conditions are derived for arbitrary Stokes number and to second order in the Knudsen number. The first-order steady boundary conditions for the velocity and temperature are found to be unaffected by oscillatory flow. In contrast, the second-order boundary conditions are modified relative to the steady case, except for the velocity component tangential to the solid wall. Application of this general asymptotic theory is explored for the oscillatory thermal creep problem, for which unsteady effects manifest themselves at leading order.
Convective effects and the role of quadrupole sources for aerofoil aeroacoustics
Authors: Wolf William R. , Azevedo João Luiz F. , Lele Sanjiva K. 
Published: August 2012

AbstractThe present investigation of aerofoil self-noise generation and propagation concerns the effects of mean flow and quadrupole sources on the broadband noise that arises from the interaction of turbulent boundary layers with the aerofoil trailing edge and the tonal noise that arises from vortex shedding generated by laminar boundary layers and trailing-edge bluntness. Compressible large-eddy simulations (LES) are conducted for a NACA0012 aerofoil with rounded trailing edge for four flow configurations with different angles of incidence, boundary layer tripping configurations and free-stream Mach numbers. The Reynolds number based on the aerofoil chord is fixed at ${\mathit{Re}}_{c} = 408\hspace{0.167em} 000$. The acoustic predictions are performed by the Ffowcs Williams & Hawkings (FWH) acoustic analogy formulation and incorporate convective effects. Surface and volume integrations of dipole and quadrupole source terms appearing in the FWH equation are performed using a three-dimensional wideband multi-level adaptive fast multipole method (FMM) in order to accelerate the calculations of aeroacoustic integrals. In order to validate the numerical solutions, flow simulation and acoustic prediction results are compared to experimental data available in the literature and good agreement is observed in terms of both aerodynamic and aeroacoustic results. For low-Mach-number flows, quadrupole sources can be neglected in the FWH equation and mean flow effects appear only for high frequencies. However, for higher speeds, convection effects are relevant for all frequencies and quadrupole sources have a more pronounced effect for medium and high frequencies. The convective effects are most readily observed in the upstream direction.
Momentum and energy of a solitary wave interacting with a submerged semi-circular cylinder
Authors: Klettner Christian A. , Eames Ian 
Published: August 2012

AbstractThe interaction of a weakly viscous solitary wave with a submerged semi-circular cylinder was examined using high-resolution two-dimensional numerical calculations. Two simulations were carried out: (a) as a baseline calculation, the propagation of a solitary wave over uniform depth; and (b) a solitary wave interacting with a submerged semi-circular cylinder. Large-scale simulations were performed to resolve the viscous boundary layers on the free surface, bottom and around the obstacle. Integral measures such as momentum and energy are analysed and compared against analytical approximations. For uniform depth, the loss in momentum and energy arises from the traction caused by the finite length of the domain bottom and the dissipation which is predominantly within the bottom boundary layer, respectively. The force on the cylinder is composed of (form) drag, inertial and hydrostatic components, the last factor arising from gradients in the height of the free surface. Morison’s semi-empirical equation is shown to provide a leading-order description of the force on the semi-circular cylinder. These elevated rates of change (momentum and energy) return to uniform depth values after a short period of time, indicating a localized effect of the obstacle. To interpret the flow field, vorticity, streamline and second invariant of the velocity gradient tensor plots were used to highlight relative thickness of boundary layers, vorticity distribution throughout the domain and stagnation points in the flow.
Transmission of acoustic-gravity waves through gas–liquid interfaces
Authors: Godin Oleg A. , Fuks Iosif M. 
Published: August 2012

AbstractIt was demonstrated recently that gas–liquid interfaces, which are usually almost perfect reflectors of acoustic waves, become anomalously transparent, and the power flux in the wave transmitted into the gas increases dramatically, when a compact sound source in the liquid approaches the interface within a fraction of the wavelength (Godin, Phys. Rev. Lett., vol. 97, 2006b, 164301). Powerful underwater explosions and certain natural sources, such as underwater landslides, generate very low-frequency waves in water and air, for which fluid buoyancy and compressibility simultaneously serve as restoring forces. In this paper, analysis of sound transmission through gas–liquid interfaces is extended to acoustic-gravity waves (AGWs) and applied to the air–water interface. It is found that, as for sound, the interface becomes anomalously transparent for sufficiently shallow compact sources of AGWs. Depending on the source type, the increase of a wave power flux into gas due to diffraction effects can reach several orders of magnitude. The physical mechanisms responsible for the anomalous transparency are discussed. Excitation of an interface wave by a point source in the liquid is shown to be an important channel of AGW transmission into the gas, which has no counterpart in the case of sound.
Vitamin D status of Irish adults: findings from the National Adult Nutrition Survey
Authors: Cashman Kevin D. , Muldowney Siobhan , McNulty Breige , Nugent Anne , FitzGerald Anthony P. , Kiely Mairead , Walton Janette , Gibney Michael J. , Flynn Albert 
Published: August 2012

Previous national nutrition surveys in Irish adults did not include blood samples; thus, representative serum 25-hydroxyvitamin D (25(OH)D) data are lacking. In the present study, we characterised serum 25(OH)D concentrations in Irish adults from the recent National Adult Nutrition Survey, and determined the impact of vitamin D supplement use and season on serum 25(OH)D concentrations. Of the total representative sample (n1500, aged 18+ years), blood samples were available for 1132 adults. Serum 25(OH)D was measured via immunoassay. Vitamin D-containing supplement use was assessed by questionnaire and food diary. Concentrations of serum 25(OH)D were compared by season and in supplement users and non-users. Year-round prevalence rates for serum 25(OH)D concentration < 30, < 40, < 50 and < 75 nmol/l were 6·7, 21·9, 40·1 and 75·6 %, respectively (11·1, 31·1, 55·0 and 84·0 % in winter, respectively). Supplement users had significantly higher serum 25(OH)D concentrations compared to non-users. However, 7·5 % of users had winter serum 25(OH)D < 30 nmol/l. Only 1·3 % had serum 25(OH)D concentrations >125 nmol/l. These first nationally representative serum 25(OH)D data for Irish adults show that while only 6·7 % had serum 25(OH)D < 30 nmol/l (vitamin D deficiency) throughout the year, 40·1 % had levels considered by the Institute of Medicine as being inadequate for bone health. These prevalence estimates were much higher during winter time. While vitamin D supplement use has benefits in terms of vitamin D status, at present rates of usage (17·5 % of Irish adults), it will have only very limited impact at a population level. Food-based strategies, including fortified foods, need to be explored.
Estimating remission from untreated major depression: a systematic review and meta-analysis
Authors: Whiteford H. A. , Harris M. G. , McKeon G. , Baxter A. , Pennell C. , Barendregt J. J. , Wang J. 
Published: August 2012

BackgroundFew studies have examined spontaneous remission from major depression. This study investigated the proportion of prevalent cases of untreated major depression that will remit without treatment in a year, and whether remission rates vary by disorder severity.MethodWait-list controlled trials and observational cohort studies published up to 2010 with data describing remission from untreated depression at ⩽2-year follow-up were identified. Remission was defined as rescinded diagnoses or below threshold scores on standardized symptom measures. Nineteen studies were included in a regression model predicting the probability of 12-month remission from untreated depression, using logit transformed remission proportion as the dependent variable. Covariates included age, gender, study type and diagnostic measure.ResultsWait-listed compared to primary-care samples, studies with longer follow-up duration and older adult compared to adult samples were associated with lower probability of remission. Child and adolescent samples were associated with higher probability of remission. Based on adult samples recruited from primary-care settings, the model estimated that 23% of prevalent cases of untreated depression will remit within 3 months, 32% within 6 months and 53% within 12 months.ConclusionsIt is undesirable to expect 100% treatment coverage for depression, given many will remit before access to services is feasible. Data were drawn from consenting wait-list and primary-care samples, which potentially over-represented mild-to-moderate cases of depression. Considering reported rates of spontaneous remission, a short untreated period seems defensible for this subpopulation, where judged appropriate by the clinician. Conclusions may not apply to individuals with more severe depression.
Longitudinal predictors of Chinese word reading and spelling among elementary grade students
Authors: YEUNG PUI-SZE , HO CONNIE SUK-HAN , WONG YAU-KAI , CHAN DAVID WAI-OCK , CHUNG KEVIN KIEN-HOA , LO LAP-YAN 
Published: August 2012

ABSTRACTThe longitudinal predictive power of four important reading-related skills (phonological skills, rapid naming, orthographic skills, and morphological awareness) to Chinese word reading and writing to dictation (i.e., spelling) was examined in a 3-year longitudinal study among 251 Chinese elementary students. Rapid naming, orthographic skills, and morphological awareness assessed in Grade 1 were significant longitudinal predictors of Chinese word reading in Grades 1 to 4. As for word spelling, rapid naming was the only significant predictor across grades. Morphological awareness was a robust predictor of word spelling in Grade 1 only. Phonological skills and orthographic skills significantly predicted word spelling in Grades 2 and 4. After controlling for autoregressive effects, morphological awareness and orthographic skills were the significant longitudinal predictors of Chinese word reading and word spelling, respectively. These findings reflected the impacts of the Chinese orthography on children's reading and spelling development.