bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical management of rectal gastrointestinal stromal tumors
Authors: Tielen Ronald , Verhoef Cornelis , van Coevorden Frits , Reyners Anna K. , van der Graaf Winette T.A. , Bonenkamp Johannes J. , van Etten Boudewijn , de Wilt Johannes H.W. 
Published: July 2012

AbstractBackgroundFive percent of gastrointestinal stromal tumors (GISTs) are primarily localized in the rectum. We analyzed the outcome of multimodality treatment for rectal GIST in a multicenter retrospective series.MethodsAll surgically treated patients with a rectal GIST were identified from four specialized centers in the Netherlands. Primary endpoints were disease‐free survival (DFS) and overall survival (OS).ResultsThirty‐two patients (22 men and 10 women) with rectal GISTs were identified. Twenty‐two patients received imatinib before surgery for a median of 9 (range 2–53) months (Group 1). Ten patients received no imatinib because of small tumor size or lack of availability (Group 2). Median tumor size before treatment was 9.3 (range 6–17) cm in Group 1 and median 6 (range 4–14) cm in Group 2. A complete resection was possible in 17/22 (77%) patients in Group 1 versus 7/10 (70%) in Group 2. Median DFS was not reached in Group 1, while it was 36 months in Group 2. Median OS was not reached in both groups.ConclusionsPreoperative imatinib leads to downsizing of the tumors in Group 1. However, it has not led to less extensive surgery. The DFS is longer in patients treated with pre‐ and post‐operative imatinib, without an effect on OS. J. Surg. Oncol. 2013;107:320–323. © 2012 Wiley Periodicals, Inc.
Bayesian uncertainty quantification of recent shock tube determinations of the rate coefficient of reaction H + O2→ OH + O
Authors: Miki Kenji , Cheung Sai Hung , Prudencio Ernesto E. , Varghese Philip L. 
Published: July 2012

AbstractWe analyze the ignition delay in hydrogen–oxygen combustion and the important chain ‐branching reaction H + O2→ OH + O that occurs behind the shock waves in shock tube experiments. We apply a stochastic Bayesian approach to quantify uncertainties in the theoretical model and experimental data. The approach involves a statistical inverse problem, which has four “components” as input information: (a) model, (b) prior joint probability density function (PDF) of the uncertain parameters, (c) experimental data, and (d) uncertainties in the scenario parameters. The solution of this statistical inverse problem is a posterior joint PDF of the uncertain parameters from which we can easily extract statistical information. We first perform a parametric study to investigate how the level of the total uncertainty (which we define as the sum of model uncertainty and experimental uncertainty) affects the uncertainty in the rate coefficient k1 of the reaction H + O2→ OH + O, which is “most likely” expressed by k1=1.73×1023T−2.5exp(−11550/T) cm3 mol−1 s−1 over the experimental temperature range 1100–1472 K. We also introduce the idea of “irreducible” uncertainty when considering other parameters in the system. After statistically calibrating the parameters modeling the rate coefficient k1, we predict its 95% confidence interval (CI) for different temperature regimes and compare the CI against the values of k1 obtained deterministically. Our results show that a small uncertainty in gas temperature (±5 K) introduces appreciable uncertainty in k1. © 2012 Wiley Periodicals, Inc. Int J Chem Kinet 44: 586–597, 2012
Functional Poly(Dimethyl Aminoethyl Methacrylate) by Combination of Radical Ring‐Opening Polymerization and Click Chemistry for Biomedical Applications
Authors: Maji Samarendra , Mitschang Fabian , Chen Lina , Jin Qiao , Wang Youxiang , Agarwal Seema 
Published: July 2012

AbstractIn this work, the macromolecular design and modular synthesis of degradable and biocompatible copolymers via radical polymerization and click chemistry is highlighted and the resulting systems are evaluated as gene delivery carriers. Poly(ethylene glycol) (PEG) grafted poly[2‐methylene‐1,3‐dioxepane (MDO)‐co‐propargyl acrylate (PA)‐co‐2‐(dimethyl aminoethyl methacrylate (DMAEMA)] (MPD) is synthesized using radical polymerization and azide‐alkyne click chemistry. The polymers are less cytotoxic and are able to condense plasmid DNA into nanosized particles. The low transfection efficiency of polyplexes in HepG2 cells is significantly improved by mixing Tat peptide with polyplexes.
On the Nature of the Breath Figures Self‐Assembly in Evaporated Polymer Solutions: Revisiting Physical Factors Governing the Patterning
Authors: Bormashenko Edward , Balter Sagi , Aurbach Doron 
Published: July 2012

AbstractThe breath‐figures self‐assembly process was studied. Polystyrene and polycarbonate were dissolved in a diversity of solvents including, acetone, dichloromethane, chloroform, carbon tetrachloride, tetrahydrofuran, toluene, xylenes, carbon disulfide, and N‐N dimethylformamide, and then were evaporated in a humid atmosphere. It was demonstrated that all solutions when sufficiently pre‐cooled gave rise to typical “breath‐figures” patterns. Thus, the decisive factor affecting the formation of the breath‐figures pattern is the temperature of the solution. Wetting properties of the manufactured patterns are reported.
Structure and Properties of Cellulose Films Reinforced by Chitin Whiskers
Authors: Huang Yao , Zhang Lina , Yang Juan , Zhang Xianzheng , Xu Min 
Published: July 2012

AbstractCytocompatible nanocomposite films are prepared by blending α‐chitin whiskers and cellulose solution in NaOH/urea. Structure and properties of the chitin/cellulose composite films are characterized by FT‐IR, XRD, 13C NMR, SEM, UV‐Vis, TGA, and tensile tests. The results reveal that the chitin whiskers are dispersed homogeneously, leading to good miscibility and properties of the chitin/cellulose composite films. By varying the chitin whisker content, the tensile strength and elastic modulus of the films can be controlled. HeLa and T293 cells are seeded onto the surfaces of the nanocomposite films, showing that the composite films were nontoxic to both cell types and that the addition of chitin whiskers promotes cell adhesion and proliferation. magnified image
Verification of Selected Key Assumptions for the Analysis of Depth‐Sensing Indentation Data
Authors: Rettler Erik , Kranenburg Johannes M. , Hoeppener Stephanie , Hoogenboom Richard , Schubert Ulrich S. 
Published: July 2012

AbstractMethods for indentation analysis involve assumptions that may be problematic for visco‐elastic materials. Three assumptions are discussed: (1) the unloading is predominantly elastic, (2) tip/sample adhesion and friction are negligible, and (3) no cracking occurs around the indent. A series of copolymers is investigated by indentation at room temperature, just below their glass transitions. Closer to the glass transition assumptions (1) and (2) were violated. Erroneous analysis due to extensive creep was identified by comparison of the creep rate at the end of the hold period with the unloading displacement rate and from the power of the fit to the unloading response. Assumption (3) was studied by scanning the indenter tip over the residual indent in polystyrene, which is known to be susceptible to stress localization. magnified image
Strategies for the Synthesis of Poly(2‐Oxazoline)‐Based Hydrogels
Authors: Kelly Andrew M. , Wiesbrock Frank 
Published: July 2012

AbstractPoly(2‐oxazoline)‐based networks currently receive great interest due to their versatile properties that can be tailor made by desktop‐planned modifications. This feature summarizes strategies for the preparation of these networks, comprising the in situ cross‐linking as well as polymer‐analogous cross‐linking routines such as (reversible) complex formation, physical processes, and covalent bond formation (involving reactions with olefinic species as well as with epoxides, isocyanates, aldehydes, acids, and their derivatives). Reflecting prominent application examples in the biomedic(in)al sector, poly(2‐oxazoline)‐co‐polyester networks are described in a dedicated section.
Evaluation of the Electrophilicites and Band Gaps of Conductive Polymers: A New Model
Authors: Noorizadeh Siamak , Shakerzadeh Ehsan 
Published: July 2012

AbstractIt is shown that the obtained hardness and electrophilicity values of the short length oligomers for a heterocyclic conductive polymer from density functional theory method are quadraticly correlated to those obtained from semiempirical method. Therefore these quantities for all oligomers (up to 15 repeating units) are predicted using the obtained quadratic relations. Both of these predicted quantities for different oligomers are fitted to a new exponential model (Y = Y∞ ed/n) to estimate the electronic properties for the considered conjugated polymers. The calculated band gaps from this model show better agreement with the reported experimental data than those predicted by the previous models. Because of a wide range of variations, the electrophilicity could be a better index for investigating the doping effect in polymers than the hardness. magnified image
Phenotypic variability of parkin mutations in single kindred
Authors: Koentjoro Brianada , Park Jin‐Sung , Ha Ainhi Duy , Sue Carolyn M. 
Published: July 2012

AbstractBackground:Mutations in parkin have been associated with autosomal recessive early‐onset Parkinson's disease (PD). Here, we report on unusual phenotypic variability within a family with mutations in parkin.Methods:The proband and her parents were clinically assessed. Mutation analysis was performed using genomic DNA and complementary DNA. The protein expression of Parkin and Mitofusin 2 was examined by western blotting.Results:The proband was a compound heterozygote with no detectable Parkin and presented with early‐onset PD. The father, a single heterozygote with reduced expression of Parkin, had mild loss of arm swing. The mother, who had only very mild rigidity, was unexpectedly found to be a homozygote with no Parkin expression. The proband, but not the parents, met the Queen Square Brain Bank criteria for PD. Parkin‐dependent ubiquitination of Mitofusin 2 was impaired in the mother and the proband.Conclusion:We report the first case of a homozygous mutation carrier in parkin who had no functional protein and only mild signs of parkinsonism in her seventh decade, whereas her daughter developed typical early‐onset PD. This family demonstrates phenotypic variability in parkin‐related parkinsonism. © 2012 Movement Disorder Society
Higher order modes in acoustically antiguiding optical fiber
Authors: Dragic Peter D. , Law Pi‐Cheng , Liu Yuh‐Shiuan 
Published: July 2012

AbstractWe present evidence of the presence of higher order acoustic modes in acoustically antiguiding optical fiber. Microwave heterodyne measurements (∼11 GHz) on a fiber with a pure silica core and F‐doped cladding reveal a Brillouin gain spectrum with two distinguishable acoustic modes. A simple model calculates the measured spectrum very well. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2347–2349, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27049
Comparison of compact electric‐LC resonators for negative permittivity metamaterials
Authors: Dhouibi Abdallah , Burokur Shah Nawaz , de Lustrac André , Priou Alain 
Published: July 2012

AbstractVarious easy made planar electric meta‐atoms are presented as alternative designs to the conventional electric‐LC resonator for achieving negative permittivity. Transforming the LC topology of the resonator helps to facilitate transposition of geometrical parameters for the optical regime and also to improve the metamaterial homogeneity. Our approach aims to simplify the resonator design and achieve a lower resonance frequency without being limited by fabrication techniques. A parametric sweep is performed to evaluate the influence of the different geometrical parameters on the resonance frequencies of the meta‐atoms. The electromagnetic behavior is investigated through both simulations and experiments in the microwave regime. Our results show that the developed meta‐atoms exhibit a purely strong electric response to normally incident radiation and can be used very effectively in producing materials with negative permittivity. For instance, a Z‐shaped structure is shown to present a higher effective medium ratio. The proposed meta‐atoms can find various applications in planar high‐frequency passive circuits due the simplicity of fabrication. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2287–2295, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27050
Compact fork stub‐loaded square open‐loop bandpass filter for VSAT applications
Authors: Maharjan Ram K. , Shrestha Bhanu , Kim Nam Young 
Published: July 2012

AbstractA compact stub‐coupled microstrip square open‐loop resonator‐based bandpass filter (BPF) is proposed.In this work, a back‐to‐back fork‐shaped open stub and two attached stubs are internally accommodated inside the square loops using open gaps. Significantly, large coupling coefficient value can be obtained in the square open‐loop resonator using those loaded stubs. In this design structure, the inserted stubs enhance to couple the two loops electromagnetically to each other. The proposed filter has strong electric coupling, because the open sides of the two coupled loops are proximately placed face‐to‐face in parallel. Similarly, the rectangular stubs attached with the internal wall of loops help to connect magnetic couplings between the two loops, as a result, the mixed coupling generates strong electromagnetic coupling in the BPF with an adequate input reflection coefficient and broader bandwidth in required frequency band. The open‐loop BPF at 14.4 GHz is realized by an embedded open‐stub combined with attach‐stubs. The designed filter shows the simple topology, low insertion losses, and sharp rejections. The S‐parameter response of the fabricated filter closely matches with the simulation results and, therefore, the feasibility of the proposed filter is confirmed. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2412–2416, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27054
Wavelength‐spacing tunable multiwavelength fiber optical parametric oscillator
Authors: Sun Bing , Hu Kai , Chen Daru , Wei Yizhen , Chen Hongzhi , Gao Shiming 
Published: July 2012

AbstractWe proposed a multiwavelength fiber optical parametric oscillator (MW‐FOPO) based on a tunable Mach–Zehnder interferometer.Multiwavelength lasing of the MW‐FOPO with a wavelength spacing of about 0.32 nm in a wavelength regime from 1515 to 1600 nm (for lasing wavelengths with the power that exceeds −60 dBm) is achieved. Wavelength spacing of the MW‐FOPO can be continuously tuned and multiwavelength lasing with wavelength spacings of 0.08, 0.16, 0.32 nm are demonstrated. The stability of the MW‐FOPO at room temperature is discussed and experimentally demonstrated. We also present the comparison of the output spectra between the MW‐FOPO and the multiwavelength Erbium‐doped fiber laser. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2405–2408, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27069
Dual‐wideband branch‐line coupler based on a loaded N‐segment SIR
Authors: Nosrati Mehdi , Daneshmand Mojgan 
Published: July 2012

AbstractIn this study, a novel topology of loaded N‐segment stepped‐impedance resonator (SIR) is introduced to control the frequency ratio between the second and first resonance frequencies of such resonator. The fundamental characteristic of such resonators, the frequency ratio between the second and first resonance frequencies, is targeted as a key factor in arbitrary tuning the resonance frequencies. It is shown that this factor can be determined in a ratio of 6.7: 2.7: 2.25 for the proposed, the conventional dual‐section and T‐shaped SIRs using a five‐segment SIR. This concept can be applied in the design of any dual‐band microwave components where a wide branch‐line couplers is chosen as a sample. It is demonstrated that the proposed topology not only provides more design flexibilities but also improves the performance of such components in terms of bandwidth enhancement, better return loss, and size reduction around 56%. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2300–2303, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27076
Design of small planar antennas based on double‐layered CRLH metamaterials
Authors: Abd El‐Raouf Hany E. , Zaheer Sulaiman Syed 
Published: July 2012

AbstractThis letter presents the design of a new efficient double negative metamaterial antennas. The design of the unit cell of these antennas is based on the composite right/left‐handed (CRLH) transmission line model. The zeroth‐order resonance of this kind of antennas depends mainly on the equivalent circuit of the unit cell and provides the opportunity to design the antenna with very small electrical size. The previous published results show that the conventional CRLH mushroom radiator suffers from narrow bandwidth and low gain. In this letter, we introduce a new method of design of CRLH metamaterial antennas to tackle the above problem using two layers of CRLH mushroom structure. The upper layer of the CRLH is used to reduce the reactance of the small antenna and to improve the matching between the antenna and the feeding line. The results at the zeroth‐order resonance show improvements in the antenna gain and bandwidth by introducing the upper layer. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2224–2229, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27078
Wideband divide‐by‐2 quadrature injection‐locked frequency dividers with large output voltage swing
Authors: Chou Li‐Te , Huang Jhin‐Fang , Jang Sheng‐Lyang 
Published: July 2012

AbstractThis letter presents a quadrature injection‐locked frequency divider (QILFD) to achieve high‐speed, wide‐locking range, accurate quadrature output phases, and large output voltage swing.The QILFD consists of two differential top‐series‐injected injection‐locked frequency dividers coupled by four parasitic bipolar junction transistors (BJTs). The MOSFET with the coupling BJT is used as a top‐series RF injector and linear mixer. The proposed QILFD has been implemented with the TSMC 0.13‐μm CMOS technology and the core power consumption is 6.02 mW at the supply voltage of 0.8 V. The operation range is from 9.2 to 12.8 GHz while the input power is 0 dBm. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2284–2287, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27089
Design of Ku‐band reflectarray using hexagonal patch with crossed slots
Authors: Park Jae Hyun , Choi Hak Keun , Kim Seon Hye 
Published: July 2012

AbstractThe microstrip reflectarray is rapidly becoming an attractive alternative solution to the traditional parabolic reflector antenna due to its various advantages, such as its high gain, narrow beam with low side lobes, light weight, and smaller volume. In this article, a microstrip reflectarray consisting of a hexagonal patch with crossed slots as the cell elements printed on a conductor‐backed substrate is proposed to replace the traditional parabolic reflector antenna. Using this type of cell element, the simulated results of the microstrip reflectarray demonstrate a radiation efficiency of over 60% at 12.5 GHz and a gain of over 26 dBi at 12–13.7 GHz. The experimental results show good agreement with the simulated ones, confirming the validity of the approach presented herein. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2383–2387, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27095
A Quad‐Band printed planar inverted‐F antenna with a quasi‐rectangular loop for mobile phones
Authors: Ahn Jungho , Choi Junho , Kim Seunghwan , Lee Jaeho , Kim Austin S. , Kim Y.‐S. 
Published: July 2012

AbstractIn this letter, a printed planar inverted‐F antenna is proposed for a quad‐band operation.The proposed quasi‐rectangular loop configuration yields the first and second resonant frequencies at 900 and 1800 MHz, respectively. The additional shorted strip on the bottom can expand the bandwidth at the upper band. The proposed antenna area is 8 × 38 mm2 and the ground size is 72 × 40 mm2. The measured impedance bandwidth, determined by 3:1 VSWR, has fully covered the GSM900 (880–960 MHz), DCS (1710–1880 MHz), PCS (1850–1990 MHz), and UMTS (1920–2170 MHz) frequency bands. The measured gain is higher than −1 dBi over the entire quad‐band. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2337–2341, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27099
Drain‐source voltage and current waveforms measurement method using harmonic ABCD matrices
Authors: Shin Suk‐Woo , Choi Jin‐Joo , Choi Jun‐Ho , So Joon‐Ho 
Published: July 2012

AbstractIn this article, a drain‐source voltage and current waveforms measurement method for a fabricated power amplifier is presented. Harmonic components of the drain‐source voltage and the current were obtained using measured output voltage and harmonic ABCD matrices of a load matching network. The drain‐source voltage and current waveforms of a fabricated power amplifier that is operated nonlinearly were successively measured using the proposed measurement method without any influence in the power amplifier operation. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2335–2337, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27100
Reliable gamma aminobutyric acid measurement using optimized PRESS at 3 T
Authors: Napolitano Antonio , Kockenberger Walter , Auer Dorothee P. 
Published: July 2012

AbstractGamma aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the central nervous system and there is strong interest in noninvasive measurement of GABA levels to assess GABAergic dysfunction in a number of psychiatric and neurological diseases. GABA detection by proton MR spectroscopy is challenging due to its low concentration as well as its strong overlap with more highly concentrated metabolites; therefore, editing techniques are typically required. In this study, the parameters of a standard point resolved spectroscopy (PRESS) sequence were optimized through repeated simulations to reliably and simultaneously detect GABA and glutamate at 3 T. Experimental validation of the optimized sequence parameters of echo time (TE1) = 15 ms and TE = 105 ms and careful postprocessing with realignment yielded reliable GABA estimates in the anterior cingulate cortex and precuneus region with test‐retest coefficient of variation of 10.4%. The achieved reproducibitilty was thus similar to published MEGA‐PRESS data despite smaller voxels and shorter scan time in this study. In conclusion, the optimized sequence parameters reported here allow reliable GABA estimation without additional hardware or software adaptation on clinical scanners. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.