bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Typologies of Islamic Thought: Mapping The Contemporary Intellectual Movements in Indonesia
Authors: Amin Faizal 
Published: June 2024

The continuity and change of reformation ideas in the history of the Islamic intellectual movement necessitate a systematic categorization. This article endeavors to present a fresh framework for classifying Islamic thought, drawing inspiration from Fazlur Rahman’s categories of revivalist, classical modernist, neo-revivalist, and neo-modernist. More specifically, this article examines a reclassification of Islamic thought and elaborates on its implications for the contemporary historical narrative of the Islamic intellectual movement within the Indonesian context. By undertaking a comprehensive literature review and employing a descriptive methodology for data collection and analysis, this article found out eight categories or typologies characterizing contemporary Islamic intellectual movements in Indonesia: (1) the revivalist movement, (2) the classical modernist movement, (3) the neo-revivalist movement, (4) the neo-modernist movement, (5) the traditionalist movement, (6) the neo-traditionalist movement, (7) the post-modernist movement, and (8) the post-traditionalist movement. These typologies commence with the emergence of classical modernism juxtaposed against classical traditionalism as the turning point of the dialectical progression of Indonesian Islamic intellectualism. Each typology has undergone a transformative process and metamorphosis within a dynamic scientific dialectic.
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis
Authors: Kharbanda Jyotsna , Mazumder Rupa , Bhardwaj Snigdha , Mazumder Avijit , Mishra Rakhi , Mishra Rashmi , Kumar Bimlesh 
Published: June 2024

:
Arthritis, a prevalent inflammatory joint condition, presents challenges for effective
therapeutic interventions, with conventional treatments often limited in efficacy and associated
with adverse effects. Recent years have witnessed a growing interest in exploring natural compounds,
particularly phytoconstituents, renowned for their anti-inflammatory and joint-protective
properties. This review aims to illuminate the potential of employing nanotherapeutic approaches
with phytoconstituents for enhanced arthritis management. The integration of nanotechnology
with phytoconstituents emerges as a promising strategy, addressing limitations in traditional arthritis
treatments. Nanocarriers like liposomes and nanoparticles provide a platform for targeted drug
delivery, improving the bioavailability of phytoconstituents. Furthermore, the combined effects of
phytoconstituents can be leveraged to target multiple pathways in arthritis pathogenesis, including
inflammation, oxidative stress, and cartilage degradation. Key phytoconstituents, such as curcumin,
resveratrol, and quercetin, exhibit anti-inflammatory and immunomodulatory properties. Nevertheless,
their therapeutic potential is often impeded by challenges like poor solubility, stability,
and bioavailability. Nanocarriers offer solutions by enhancing pharmacokinetics and enabling sustained
release, thereby boosting overall therapeutic efficacy. The review explores the mechanisms
underlying the anti-arthritic effects of phytoconstituents and their nanoformulations, including the
modulation of pro-inflammatory cytokines, inhibition of matrix metalloproteinases, and reduction
of oxidative stress. In summary, the integration of phytoconstituents with nanotechnology presents
a promising avenue for developing targeted and effective arthritis therapies. This comprehensive
review serves as a valuable resource for researchers, clinicians, and pharmaceutical developers
seeking innovative approaches to address the intricate challenges associated with arthritis management.
Harvesting Health: Phytochemicals in Cognitive Impairment Therapy
Authors: Jain Sanidhya , Mazumder Avijit , Das Saumya , Tyagi Pankaj Kumar , Chaitanya MVNL 
Published: June 2024

Abstract::
Mild Cognitive Impairment (MCI) is swiftly emerging as a prevalent clinical concern
within the elderly demographic. Willoughby spearheaded the pioneering investigation into the
evolution of memory decline spanning from the age of 20 to 70. Employing a computerized
substitution examination, he pinpointed a zenith in memory prowess at the age of 22, signifying
the shift from infancy, succeeded by a gradual decline in later years in 1929. Cognitive impairment
impacts various facets, encompassing cognition, memory, perceptual acuity, and linguistic
proficiency. Compelling evidence indicates that genetic, dietary, and metabolic factors influence
the trajectory of cognitive decline in this patient cohort. In addition to the widely recognized
influence of the Mediterranean diet on cognitive function, numerous studies have delved
into the potential impact of diverse phytochemicals on cognitive deterioration. Many of these
compounds are renowned for their inflammation reducer or free-radical scavenger properties,
coupled with their commendable acceptability and defense profiles. Phytochemicals sourced
from medicinal plants play an essential role in upholding the intricate chemical equilibrium of
the brain by modulating receptors linked to crucial inhibitory neurotransmitters. Across the annals
of historical medicinal traditions, a multitude of plants have been cataloged for their efficacy
in mitigating cognitive disorders. This study presents a concise examination of distinct medicinal
herbs, highlighting their neuroprotective phytochemical components such as fatty acids,
phenols, alkaloids, flavonoids, saponins, terpenes, and beyond. The principal objective of this
inquiry is to meticulously inspect and provide discernment into the extant evidence concerning
phytochemicals exhibiting clinically demonstrable effects on cognitive decline
Mechanistic Review on the Role of Gut Microbiota in the Pathology of
Cardiovascular Diseases
Authors: Usman Iqra , Anwar Aamir , Shukla Shivang , Pathak Priya 
Published: June 2024

Abstract:
Cardiovascular diseases (CVDs), which stand as the primary contributors to illness and
death on a global scale, include vital risk factors like hyperlipidemia, hypertension, diabetes, and
smoking, to name a few. However, conventional cardiovascular risk factors offer only partial insight
into the complexity of CVDs. Lately, a growing body of research has illuminated that the
gut microbiome and its by-products are also of paramount importance in the initiation and progression
of CVDs. The gastrointestinal tract houses trillions of microorganisms, commonly known as
gut microbiota, that metabolize nutrients, yielding substances like trimethylamine-N-oxide (TMAO),
bile acids (BAs), short-chain fatty acids (SCFAs), indoxyl sulfate (IS), and so on. Strategies
aimed at addressing these microbes and their correlated biological pathways have shown
promise in the management and diagnosis of CVDs. This review offers a comprehensive examination
of how the gut microbiota contributes to the pathogenesis of CVDs, particularly atherosclerosis,
hypertension, heart failure (HF), and atrial fibrillation (AF), explores potential underlying
mechanisms, and highlights emerging therapeutic prospects in this dynamic domain.
AUTHENTICITY AND UNIQUENESS OF ASINAN BOGOR AS A DISTINCTIVE CULINARY DELIGHT OF BOGOR CITY
Authors: Putri Ardaneswara , Ramdhani Rafy , Rosalia Melva , Arraniri Fahma Faradisa , Kurnia Insan , Rahayu Kania Sofiantina 
Published: June 2024

Asinan bogor, commonly known as Bogor salty pickles, represents a traditional delicacy of Bogor, Indonesia, consisting of processed vegetables and fruits consumed raw alongside various additional ingredients. This research aims to delve into the uniqueness of asinan bogor. The study was conducted through surveys interviews, and questionnaires administered to 40 asinan Bogor sellers in Bogor City. Sellers unanimously recognize asinan bogor as a Bogor traditional dish. Sellers exhibit the highest level of knowledge concerning raw materials, with history being their least familiar aspect. While no main ingredients are obligatory, specific components hold priority, such as bean sprouts for vegetables pickled; and mango, water guava, and jicama for fruits pickled. Mandatory seasoning ingredients include ground red chili, salt, and water. The composition of asinan ingredients varies based on consumer preferences. Antanan is rarely utilized as a primary ingredient, whereas salted mustard green epitomizes Chinese cuisine. Currently, the serving of asinan bogor is predominantly in plastic packaging, deviating from on-site consumption, particularly for souvenir packaging. The paramount uniqueness of the asinan bogor lies in the gravy.
A Patient-Driven Mobile Health Innovation in Cystic Fibrosis Care: Comparative Cross-Case Study
Authors: Mazzocato Pamela , Luckhaus Jamie Linnea , Malmqvist Castillo Moa , Burnett Johan , Hager Andreas , Oates Gabriela , Wannheden Carolina , Savage Carl 
Published: June 2024

Background
Patient-driven innovation in health care is an emerging phenomenon with benefits for patients with chronic conditions, such as cystic fibrosis (CF). However, previous research has not examined what may facilitate or hinder the implementation of such innovations from the provider perspective.

Objective
The aim of this study was to explain variations in the adoption of a patient-driven innovation among CF clinics.

Methods
A comparative multiple-case study was conducted on the adoption of a patient-controlled app to support self-management and collaboration with health care professionals (HCPs). Data collection and analysis were guided by the nonadoption, abandonment, spread, scale-up, and sustainability and complexity assessment tool (NASSS-CAT) framework. Data included user activity levels of patients and qualitative interviews with staff at 9 clinics (n=8, 88.9%, in Sweden; n=1, 11.1%, in the United States). We calculated the maximum and mean percentage of active users at each clinic and performed statistical process control (SPC) analysis to explore how the user activity level changed over time. Qualitative data were subjected to content analysis and complexity analysis and used to generate process maps. All data were then triangulated in a cross-case analysis.

Results
We found no evidence of nonadoption or clear abandonment of the app. Distinct patterns of innovation adoption were discernable based on the maximum end-user activity for each clinic, which we labeled as low (16%-23%), middle (25%-47%), or high (58%-95%) adoption. SPC charts illustrated that the introduction of new app features and research-related activity had a positive influence on user activity levels. Variation in adoption was associated with providers’ perceptions of care process complexity. A higher perceived complexity of the value proposition, adopter system, and organization was associated with lower adoption. In clinics that adopted the innovation early or those that relied on champions, user activity tended to plateau or decline, suggesting a negative impact on sustainability.

Conclusions
For patient-driven innovations to be adopted and sustained in health care, understanding patient-provider interdependency and providers’ perspectives on what generates value is essential.
Influence of Model Evolution and System Roles on ChatGPT’s Performance in Chinese Medical Licensing Exams: Comparative Study
Authors: Ming Shuai , Guo Qingge , Cheng Wenjun , Lei Bo 
Published: June 2024

Abstract

Background
With the increasing application of large language models like ChatGPT in various industries, its potential in the medical domain, especially in standardized examinations, has become a focal point of research.

Objective
The aim of this study is to assess the clinical performance of ChatGPT, focusing on its accuracy and reliability in the Chinese National Medical Licensing Examination (CNMLE).

Methods
The CNMLE 2022 question set, consisting of 500 single-answer multiple choices questions, were reclassified into 15 medical subspecialties. Each question was tested 8 to 12 times in Chinese on the OpenAI platform from April 24 to May 15, 2023. Three key factors were considered: the version of GPT-3.5 and 4.0, the prompt’s designation of system roles tailored to medical subspecialties, and repetition for coherence. A passing accuracy threshold was established as 60%. The χ2 tests and κ values were employed to evaluate the model’s accuracy and consistency.

Results
GPT-4.0 achieved a passing accuracy of 72.7%, which was significantly higher than that of GPT-3.5 (54%; P<.001). The variability rate of repeated responses from GPT-4.0 was lower than that of GPT-3.5 (9% vs 19.5%; P<.001). However, both models showed relatively good response coherence, with κ values of 0.778 and 0.610, respectively. System roles numerically increased accuracy for both GPT-4.0 (0.3%‐3.7%) and GPT-3.5 (1.3%‐4.5%), and reduced variability by 1.7% and 1.8%, respectively (P>.05). In subgroup analysis, ChatGPT achieved comparable accuracy among different question types (P>.05). GPT-4.0 surpassed the accuracy threshold in 14 of 15 subspecialties, while GPT-3.5 did so in 7 of 15 on the first response.

Conclusions
GPT-4.0 passed the CNMLE and outperformed GPT-3.5 in key areas such as accuracy, consistency, and medical subspecialty expertise. Adding a system role insignificantly enhanced the model’s reliability and answer coherence. GPT-4.0 showed promising potential in medical education and clinical practice, meriting further study.
Digital Gamification Tool (Let’s Control Flu) to Increase Vaccination Coverage Rates: Proposal for Algorithm Development
Authors: Lopes Henrique , Baptista-Leite Ricardo , Hermenegildo Catarina , Atun Rifat 
Published: June 2024

Background
Influenza represents a critical public health challenge, disproportionately affecting at-risk populations, including older adults and those with chronic conditions, often compounded by socioeconomic factors. Innovative strategies, such as gamification, are essential for augmenting risk communication and community engagement efforts to address this threat.

Objective
This study aims to introduce the “Let’s Control Flu” (LCF) tool, a gamified, interactive platform aimed at simulating the impact of various public health policies (PHPs) on influenza vaccination coverage rates and health outcomes. The tool aligns with the World Health Organization’s goal of achieving a 75% influenza vaccination rate by 2030, facilitating strategic decision-making to enhance vaccination uptake.

Methods
The LCF tool integrates a selection of 13 PHPs from an initial set proposed in another study, targeting specific population groups to evaluate 7 key health outcomes. A prioritization mechanism accounts for societal resistance and the synergistic effects of PHPs, projecting the potential policy impacts from 2022 to 2031. This methodology enables users to assess how PHPs could influence public health strategies within distinct target groups.

Results
The LCF project began in February 2021 and is scheduled to end in December 2024. The model creation phase and its application to the pilot country, Sweden, took place between May 2021 and May 2023, with subsequent application to other European countries. The pilot phase demonstrated the tool’s potential, indicating a promising increase in the national influenza vaccination coverage rate, with uniform improvements across all targeted demographic groups. These initial findings highlight the tool’s capacity to model the effects of PHPs on improving vaccination rates and mitigating the health impact of influenza.

Conclusions
By incorporating gamification into the analysis of PHPs, the LCF tool offers an innovative and accessible approach to supporting health decision makers and patient advocacy groups. It enhances the comprehension of policy impacts, promoting more effective influenza prevention and control strategies. This paper underscores the critical need for adaptable and engaging tools in PHP planning and implementation.

International Registered Report Identifier (IRRID)
RR1-10.2196/55613
Manejo endodóntico conservador en paciente con carcinoma metastásico. Revisión y reporte de caso
Authors: Mendiburu-Zavala Celia Elena del Perpetuo Socorro , Baeza-Denis Pamela , Carrillo-Mendiburu Josué , Peñaloza-Cuevas Ricardo 
Published: June 2024

Introducción: el carcinoma es definido como una neoplasia maligna que se forma a partir del tejido epitelial, de etiología desconocida y multifactorial, relacionada con los hábitos de consumo de tabaco y alcohol; de rápido crecimiento, destrucción tisular local y capacidad para hacer metástasis. Objetivo: presentar el manejo endodóntico conservador en un paciente con carcinoma metastásico. Presentación del caso: paciente masculino de 69 años, maya-hablante que acudió para valoración y tratamiento de los dientes 32 (con corona fenestrada) y 33, ambos sintomáticos. Durante la anamnesis refirió haber sido fumador y alcohólico, estar bajo tratamiento analgésico por dolor de masa indurada en la cadena ganglionar cervical izquierda, otitis media crónica y otorrea crónica, sin dolor ni fiebre, de un año de evolución. A la inspección clínica extraoral, se palpó la región ganglionar cervical izquierda agrandada e indurada, extendiéndose hasta el área submandibular y preauricular. Manifestó odinofagia leve y disfagia. Se diagnosticó periodontitis apical crónica (32) y necrosis pulpar parcial aséptica (33). Se realizó tratamiento de ambos dientes sin anestesia, aislamiento atraumático, apertura, tope apical, técnica de instrumentación StepBack, irrigación del conducto con hipoclorito de sodio (NaClO) al 5% para desinfección y conformación, secado y colocación de hidróxido de calcio (Ca(OH)₂), y sellado con resina. No se realizó obturación con gutapercha. Posterior al tratamiento endodóntico se realizó la interconsulta con oncología, donde se realizó biopsia del nódulo cervical izquierdo por aspiración con aguja fina, y se diagnosticó metástasis de carcinoma poco diferenciado con extensa necrosis. Se localizó tumor primario: carcinoma en laringe, por medio de ultrasonido con contraste. Conclusiones: El manejo fue conservador, por sospecha de la condición neoplásica que el paciente presentaba.
Implementasi Perijinan Minimarket di Kota Denpasar
Authors: Ni Made Puspasutari Ujianti  , A. A. Sagung Laksmi Dewi  , Luh Putu Suryani  , Anak Agung Alit Ista Damayanti  , Made Sadhu Arta Kori  
Published: June 2024

Perubahan gaya hidup dan pola konsumtif masyarakat kota yang bergeser menginginkan kemudahan dan serba praktis menyebabkan semakin maraknya pertumbuhan minimarket di kota besar khsusunya Kota Denpasar. Untuk mengantisipasi hal tersebut, Pemerintah Kota Denpasar telah membuat kebijakan Peraturan Walikota yang ditetapkan pada tahun 2009 yang diharapkan dapat mengatasi masalah penataan dan pembinaan pasar tradisional, pusat perbelanjaan, dan toko modern di Kota Denpasar. Pelaksanaan Penataan dan Pembinaan Pasar Tradisional, Pusat Perbelanjaan, dan Toko Modern di Kota Denpasar berdasarkan Peraturan Walikota Denpasar Nomor 9 Tahun 2009 wajib mengacu pada Rencana Tata Ruang Wilayah, dan Rencana Detail Tata Ruang termasuk Peraturan Zonasinya, pemenuhan syarat administrasi sebelum izin minimarket diterbitkan. Prosedur dalam menerbitkan izin untuk minimarket di Kota Denpasar dilakukan oleh lintas instansi yakni Dinas Perijinan, Dinas Perindustrian dan Perdagangan, dan Dinas Pekerjaan Umum. Setelah izin diterbitkan Tim Teknis melakukan pengawasan untuk memastikan bahwa izin yang diterbitkan telah dilaksanakan sesuai dengan peruntukannya. Dalam pelaksanaan Peraturan Walikota Nomor 9 Tahun 2009 tentang Penataan dan Pembinaan Pasar Tradisional, Pusat Perbelanjaan dan Toko Modern ini belum dapat dikatakan berjalan dengan baik, hal ini dapat di lihat dari masih banyaknya minimarket yang berdisi tidak sesuai dengan Rencana Tata Ruang Wilayah Kota Denpasar. Hal ini dikarenakan masih adanya kepentingan yang mempengaruhi pelaksanaan kebijakan penataan minimarket ini. Kepentingan yang mempengaruhi kebijakan (interest affected) berkaitan dengan berbagai kepentingan yang mempengaruhi suatu implementasi kebijakan.
Effect of printing technology and orientation on the accuracy of three-dimensional printed retainers
Authors: ElShebiny Tarek , Menezes Luciane Macedo de , Matthaios Stefanos , Tsolakis Ioannis A. , Palomo Juan Martin 
Published: June 2024

ABSTRACT

Objectives
To evaluate the impact of printer technology and print orientation on the accuracy of directly printed retainers.

Materials and Methods
Digital retainers were printed with two different printing technologies: digital light processing (DLP) and stereolithography (SLA), using two different orientations: 0° and 90°. After printing, the retainers (n = 40) were scanned using cone-beam computed tomography. The DICOM files were then converted into standard tessellation language (STL) files. Comparison of the printed retainers with a master file was done by superimposition using a three-dimensional (3D) best-fit tool in Geomagic software. A ±0.25 mm tolerance was set to detect differences between the superimposed files. Statistical analysis was conducted (Kruskal-Wallis and Wilcoxon-Mann-Whitney tests, with Bonferroni correction).

Results
The lowest median average deviation was observed for the DLP horizontally printed models (median, [interquartile range (IQR)] = 0.01 mm, [−0.01, 0.02]) followed by the SLA horizontally printed retainers (median, [IQR] = 0.05 mm, [0.03, 0.07]). The highest median inside the tolerance levels ratio was observed for the horizontally SLA printed retainers (median, [IQR] = 78.9%, [74.4, 82.4%]) followed by the horizontally DLP printed retainers (median, [IQR] = 78.2%, [74.5, 80.7%]).

Conclusions
Both technologies (DLP and SLA) showed 3D printed results compatible with orthodontic clinical needs. Printing orientation was more important than printer type regarding its accuracy. Additional studies are needed to evaluate the accuracy of direct printed appliances clinically.