bluuebunny/crossref_metadata_2025_split huggingface dataset:
БАЛАЛАРДЫҢ ТЕРІСІНДЕГІ АИТВ-ИНФЕКЦИЯСЫНЫҢ КӨРІНІСТЕРІ
Authors: Айткали М.К. , Оспанова С.А. , Суханбердиева З.М. 
Published: June 2024

Значительный прогресс был достигнут в ликвидации синдрома приобретенного иммунодефицита (СПИД) и вируса иммунодефицита (ВИЧ) среди детей, однако глобальное бремя ВИЧ-инфекции среди детей остается серьезной проблемой для работников здравоохранения во всем мире, особенно в условиях ограниченных ресурсов. В статье рассматриваются такие аспекты как эпидемиология ВИЧ-инфекции у детей, определения случая, классификация и патогенез ВИЧ-инфекции у детей, клинические проявления некоторых СПИД-индикаторных состояний и исходы ВИЧ-инфекции у детей. Особое внимание уделяется проявлениям на коже и их клиническому значению. Из данного обзора следует, что наиболее распространенными проявлениями ВИЧ-инфекции на коже у детей являются кандидоз кожи и слизистых оболочек, себорейный дерматит, бактериальные и вирусные инфекции с характерными кожными проявлениями. Показано большое клиническое значение кожных проявлений у детей, которые могут служить важными индикаторами прогрессирования ВИЧ-инфекции. Раннее выявление и лечение этих проявлений играют важную роль в предотвращении дальнейшего распространения инфекции и улучшении прогноза заболевания. Данная статья направлена на улучшение понимания характеристики ВИЧ-инфекции у детей, что может способствовать разработке более эффективных стратегий предотвращения и лечения данного серьезного заболевания.
Significant progress has been made in eliminating acquired immunodeficiency syndrome (AIDS) and immunodeficiency virus (HIV) among children, but the global burden of childhood HIV infection remains a major challenge for health care workers worldwide, especially in resource-limited settings. The article discusses such aspects as the epidemiology of HIV infection in children, case definitions, classification and pathogenesis of HIV infection in children, clinical manifestations of some AIDS-defining conditions and outcomes of HIV infection in children. Particular attention is paid to skin manifestations and their clinical significance. From this review, the most common skin manifestations of HIV infection in children are candidiasis of the skin and mucous membranes, seborrheic dermatitis, bacterial and viral infections with characteristic skin manifestations. The great clinical significance of skin manifestations in children, which can serve as important indicators of the progression of HIV infection, has been shown. Early detection and treatment of these manifestations play an important role in preventing further spread of infection and improving the prognosis of the disease. This article aims to improve our understanding of the characteristics of HIV infection in children, which may contribute to the development of more effective strategies for the prevention and treatment of this serious disease.
ГЕНОДЕРМАТОЗДАР: ЖІКТЕЛУІ ЖӘНЕ ОЛАРДЫҢ ЕРЕКШЕЛІКТЕРІ
Authors: Камалова Д.Б. 
Published: June 2024

Генодерматозы - это наследственные заболевания, которые проявляются на коже. Некоторые из этих заболеваний встречаются редко. Однако, распознавание кожных проявлений генодерматозов важно не только для начала соответствующей терапии, но и для обнаружения других сопутствующих аномалий, включая злокачественные новообразования. Генодерматозы представляют собой большую группу заболеваний, включающую несколько сотен форм. Кожные поражения могут быть единственным проявлением заболевания, но чаще они сочетаются с нарушениями других систем органов. Генодерматозы связаны с повышенным риском развития злокачественных новообразований, поэтому раннее выявление наследственной патологии является важным для профилактики онкологических заболеваний. Цель данного обзора - анализ генодерматозов, их дерматологических проявлений и генетической природы. Для этого был проведен обзор актуальной литературы, научных публикаций и медицинских баз данных за последние 5 лет. В результате обзора были выделены несколько нозологических групп генодерматозов, включающих различные заболевания с соответствующими клиническими признаками. Разнообразие клинических проявлений этих наследственных заболеваний означает, что важно уделять внимание не только общим принципам лечения, но также и различиям в клинической картине и подходящем лечении для конкретных подгрупп генодерматозов.
Genodermatoses are inherited diseases that show up on the skin. Some of these diseases are rare. However, recognising the cutaneous manifestations of genodermatoses is important not only to initiate appropriate therapy but also to detect other associated abnormalities, including malignancies. The genodermatoses are a large group of diseases comprising several hundred forms. Cutaneous lesions may be the only manifestation of the disease, but more often they are combined with disorders of other organ systems. Genodermatoses are associated with an increased risk of malignant neoplasms, so early detection of hereditary pathology is important for cancer prevention. The aim of this review is to analyse genodermatoses, their dermatological manifestations and genetic nature. For this purpose, a review of current literature, scientific publications and medical databases for the last 5 years was performed. As a result of the review, several nosological groups of genodermatoses were identified, including various diseases with corresponding clinical features. The diversity of clinical manifestations of these inherited diseases means that it is important to pay attention not only to the general principles of treatment, but also to the differences in clinical presentation and appropriate treatment for specific subgroups of genodermatoses.
Design and Validation of a Knowledge Questionnaire on Healthy Eating, Personal Hygiene, And Physical Activity (Hephpa) For 8–12-Year-Old School Children
Authors: Martínez-Royert Judith Cristina , Pájaro-Martinez María Cristina , Amador-Rodero Eulalia , Camacho Maribel Sofía Morales , Villalba-Villadiego Anuar , Collante-Caiafa Carmen , Tafur-Castillo Janery , León-García Marcela 
Published: June 2024

Introduction: Childhood obesity is a complex global challenge linked to genetic, environmental and lifestyle factors, the prevention of which requires changing habits through health promotion and education; however, there is a lack of instruments to study this reality in a comprehensive and articulated manner. Objective: Design and evaluate the reliability and validity of a questionnaire to assess the dimensions of healthy eating, personal hygiene and physical activity in children between 8 and 12 years of age. Method: For this purpose, a study with a non-experimental design was proposed, developed in 5 stages: 1) item construction, 2) content validation by experts, 3) cognitive piloting, 4) analysis of item responses, and 5) reliability assessment. The first version of the self-administered questionnaire with a preliminary battery of 67 items gave way to an initial version of the instrument with 40 questions related to the three main dimensions of the questionnaire. Content validation techniques such as the Content Validity Ratio (CVR) and the Content Validity Index (CVI) were used during the instrument validation process. The 40 items designed were rated by 3 experts. A pilot test was conducted with 221 elementary school students. Results: all items had a CVR greater than 0.5823, indicating that the instrument can be used in its current state. In addition, the CVI value obtained was 0.9650, demonstrating a high content validity of the instrument. This result is revalidated by the high number of agreements among the experts in the “Indispensable” and “Useful but not indispensable” categories (118 out of 120 possible agreements). The internal consistency of the instrument was evaluated by calculating Cronbach's alpha coefficient for the 40 items that make up the three dimensions. The alpha coefficient obtained was 0.960, indicating high reliability of the instrument. In addition, the items of each dimension were analyzed and none of them presented a Cronbach's alpha coefficient lower than 0.85. Conclusions: Content validity yielded an overall CVI of 0.9650 and Cronbach's alpha coefficient for each dimension was 0.964, 0.957 and 0.964 for food, personal hygiene and physical activity, respectively. This indicates that the instrument is internally consistent and therefore reliable. Furthermore, it can measure one, two or all three dimensions, and can be used to measure the impact of educational interventions in these areas in the school population aged 8 to 12 years.
Effect of immediate dentin sealing on the fracture strength of lithium disilicate ceramic onlays
Authors: Saadeddin Nader , Ali Al-Khalil Manar , Al-Adel Omar 
Published: June 2024

This study aimed to evaluate the effect of immediate dentin sealing (IDS) on the fracture strength of ceramic onlays when compared with delayed dentin sealing (DDS). Twenty extracted human maxillary premolars were randomly divided into 2 groups according to the dentin sealing technique (n=10). A standardized mesio-occlusal-distal cavity was prepared with reduction of the palatal cusp. The dentin surfaces of the IDS group were immediately sealed after finishing the preparation (before taking impressions, temporization, and 14-day storage at 37°C) using a bonding system (ALL-BOND 3®, ALL-BOND 3® RESIN) and flowable composite (Te-Econom Flow). Impressions were made and temporary restorations were fabricated using PRO-V FILL®. The wax patterns were milled and the onlays were fabricated by heat-pressing technique (IPS e.max Press). After bonding the final restorations with resin cement (Variolink N), the specimens were thermocycled. Fracture strength was measured using a universal testing machine (Testometric M350-10KN) at 1 mm/min until failure occurred. Student's t-test was used to evaluate the results of the fracture strength test. The failure mode was examined using a stereomicroscope. The mean fracture strength in the IDS group (1335 ± 335 N) was statistically significantly higher than that for the DDS group (931 ± 274 N) (p < 0.05). Fracture of the restoration with a small portion of the tooth was the most frequent mode of failure. Within the limitation of this in vitro study, there was an improvement in the fracture strength of ceramic onlays with the use of IDS. However, the ceramic onlays were strong enough to withstand the physiological mastication force in both groups.
MULTIDISCIPLINÁRNY PRÍSTUP K IZOLOVANEJ CHRONICKEJ DYZESTÉZII S KOŽNÝMI PREJAVMI PRI POSUDZOVANÍ BOLESTI V OBLASTI CHRBTA
Authors: Takáčová G. 
Published: June 2024

Východisko: V klinickej praxi sa často stretávame s rôznymi subjektívnymi symptómami v oblasti chrbta. Okrem bolesti to býva zvýšená citlivosť, ale aj pocity pálenia, hyperalgézie, dyzestézie alebo svrbenia. Chronická izolovaná dyzestézia (notalgia paresthetica- NP) patrí do podskupiny neuropatickej bolesti, ktorá vzniká v dôsledku torakálnej radikulopátie. Prejavuje sa ako lokalizovaná bolesť v dermatómoch Th2-Th6, spolu s inými fenoménmi neuropatickej bolesti ako sú parestézie (hypestézie) a svrbenie. Pre pacienta s ochorením notalgia paresthetica je vzhľadom na sekundárne kožné zmeny často dermatovenerológ lekárom prvého kontaktu, ktorý však v následnom terapeutickom procese zohráva len čiastkovú úlohu. Výskumy, ale aj klinická prax ukazujú, že v manažmente ochorenia je potrebný komplexný prístup viacerých špecialistov. Nakoľko tento syndróm je často združený s rôznymi funkčnými aj štrukturálnymi poruchami v oblasti chrbtice, lekár špecialista v odbore fyziatria, balneológia a liečená rehabilitácia môže mať zvlášť významnú úlohu pri zlepšení jeho diagnostiky a liečby.
The Correlation Between Classroom Seating Position and Speaking Ability of a 9th Grader
Authors: Presti Happy , Rasyid Tri Rositasari , Hartati Sri 
Published: June 2024

English is regarded as an international language, one of the most widely used languages in all fields. In Indonesia, the government recognized that English proficiency had an impact on global development not only for education but also for career purposes. English is useful in a variety of fields. The limitation of the study was only focused on “The Correlation between Classroom Seating Position and Speaking Ability of 9th Grade Students of SMP Muhammadiyah 4 Palembang”. The objectives of this study were found out whether or not there is a significant correlation between Classroom Seating Position and Speaking Ability. This study used quantitative research design with correlational approach. The researchers used a purposive sampling, total of population were 172 students and the total of sample were 27 students. The data were collected by two instruments, (1) through ready-made questionnaires, (2) speaking test was analysed by using SPSS 26. The result of this study was that there was a correlation between two variables, with r-obtained (0.797) was higher than r-table (0.388). The conclusion of this study was that the alternative hypotheses (Ha) was accepted and the null hypotheses (H0) was rejected. Then there was a high correlation between the two variables.
The antimicrobial activity of tea tree oil (Melaleuca alternifolia) and its metal nanoparticles in oral bacteria
Authors: Mohammed Afrah E. , Aldahasi Reham M. , Rahman Ishrat , Shami Ashwag , Alotaibi Modhi , BinShabaib Munerah S. , ALHarthi Shatha S. , Aabed Kawther 
Published: June 2024

Tea tree (Melaleuca alternifolia) oil (TTO) is an antimicrobial agent, and hence, its use in fabricating nanoparticles (NP) may be useful in providing more efficacious antimicrobial agents. The current research aimed to test the antimicrobial efficacy of TTO and its TTO-Metal-NPs against oral microbes: Porphyromonas gingivalis, Enterococcus faecalis, and Streptococcus mutans. The antimicrobial activity of TTO and zinc (Zn) and iron (Fe) nanoparticles (NPs) and the combined effects of antimicrobial agents were investigated using agar well diffusion assays. Fourier-transform infrared spectroscopy (FT-IR) was used to identify the phyto-constituents of TTO. Field emission scanning electron microscopy (FE-SEM), dynamic light scatter (DLS), and zeta potential were utilized to analyze the biogenic nanoparticles’ morphology, size, and potential. The antimicrobial mode of action was determined by assessing the morphological changes under scanning electron microscopy (SEM). The TTO extracts converted Zn and Fe ions to NPs, having an average size of 97.50 (ZnNPs) and 102.4 nm (FeNPs). All tested agents had significant antibacterial efficacy against the tested oral microbes. However, the TTO extract was more efficacious than the NPs. Combination treatment of TTO with antibiotics resulted in partial additive effects against P. gingivalis and partial antagonistic effects against E. faecalis, S. mutans, and common mouthwashes (Oral B and chlorhexidine). TTO and NP-treated bacteria underwent morphological changes on treatment. M. alternifolia phytochemicals could be useful for further research and development of antimicrobial NPs. The current study highlights the variance in activity observed for different types of bacteria and antagonistic effects seen with common mouthwashes, which represent a threat to therapeutic efficacy and heighten the risk of clinical microbial resistance.
Technology in Classrooms among Gen X Teachers in Basic Education Schools in Panabo City: A Case Study
Authors: C. Requillo Diocyl Ann , M. Bauyot Marleonie 
Published: June 2024

Technology is pivotal in modern education, revolutionizing teaching and learning processes. Effective management of technology resources in educational settings is crucial for maximizing their potential benefits. This research explores the experiences, challenges, and recommendations for implementing technology in classrooms among the twelve (12) Generation X teachers in Basic Education Schools in the Division of Panabo City. Hence, this study uses a qualitative case study design and purposeful sampling to select participants for basic education teaching. The research interview guide used was validated and enhanced by three (3) experts in the field of education. The three (3) primary themes of the experience were identified: easy access to information, diverse strategies for teaching, and interaction. While on the challenges of implementing technology in basic education classrooms, there are four (4) themes: poor network connections, lack of skills in ICT, insufficient budget, and unmotivated to adapt. As to the teachers' recommendations on the implementation of technology, four (4) significant themes were identified: provide ICT training, support access to resources, foster collaboration and teamwork, and adapt to the new trend. Recommendations include assessing needs and goals, professional development and support for teachers, adapting various new trends, and promoting digital competence to teachers.
The Chameleon Effect of Monochromatic Composite Resin: A Systematic Review and Meta-Analysis
Authors: Guimarães Camila Pimenta de Araújo , Torres Adriana da Silva , Oliveira Emanuelle Melquiades Barbosa de , Fehrenbach Júlia , Isolan Cristina Pereira , Araújo Cíntia Tereza Pimenta de 
Published: June 2024

Aims: The aim of this systematic review was to evaluate the optical properties of monochromatic composite resins and conventional composite resins in direct restorations in permanent teeth.
Study Design: A systematic review and meta-analysis.
Methodology: The searches were carried out in July and August, in the following databases:: Medline (PubMed), Web of Science, ScienceDirect and Google Scholar. The articles were selected, first by title, followed by reading the abstract and finally the complete work. Two independent meta-analyses were performed using Review Manager 5.4 software.
Results: Two hundred and eleven articles were found, 6 articles were included in this systematic review and, among these, 4 were included in the meta-analysis. The meta-analysis when comparing monochromatic resins and conventional composite resins, using color stability data showed greater optical performance of the monochromatic resin for subgroups A2 and A3. After analyzing the age data according to the Coffee and Tea subgroups, the monochromatic resin showed no statistical difference. For color variation during bleaching, the monochromatic resin showed statistically lower color variation. For color matching, conventional resins showed higher shade matching ability compared to monochromatic composite.
Conclusion: Therefore, the monochromatic resin presented greater color stability in shades A2 and A3 and presented better results in terms of color variation compared to the conventional composite resin after bleaching.
Nature as Measure: The Biomimicry Guild
Authors: Peters Terri 
Published: November 2011

AbstractThe potential for biomimicry lies far beyond the direct imitation of natural forms. Guest‐editor Terri Peters describes how Janine Benyus, the biologist and innovation consultant, is using biomimicry to create performance metrics from natural technologies and processes for assessing aspects of ecological and sustainable design. The Genius of the Place study that she developed with the Biomimicry Guild, for instance, provides designers with a tool for exploring and reporting on the natural and environmental features of a specific site.
Gardens by the Bay: Ecologically Reflective Design
Authors: Davey Meredith 
Published: November 2011

AbstractMeredith Davey of Atelier Ten describes how as part of a design team led by Grant Associates with architects Wilkinson Eyre, multidisciplinary engineers Atelier Ten have developed a scheme for the Gardens by the Bay, Bay South in Singapore based on first principles. Holistically integrated solutions have been sought to the central and demanding brief to create artificial interior environments that will enable Mediterranean and mountain plants to grow in the tropical urban heat of downtown Singapore. Copyright © 2011 John Wiley & Sons, Ltd.
Tumor‐specific but not nonspecific cell‐free circulating DNA can be used to monitor disease response in lymphoma
Authors: Jones Kimberley , Nourse Jamie P. , Keane Colm , Crooks Pauline , Gottlieb David , Ritchie David S. , Gill Devinder , Gandhi Maher K. 
Published: November 2011

AbstractRecently, nontumor specific circulating DNA was shown to be elevated in a broad range of lymphomas, implicating a role as a potential biomarker. Epstein‐Barr virus' (EBV) presence within a proportion of lymphomas implies EBV‐DNA has potential as a lymphoma‐specific disease response biomarker. However, application would be restricted to EBV‐associated lymphomas. Neither detailed comparison has been performed of lymphoma‐specific versus nonspecific DNA as disease response biomarkers nor have the kinetics of circulating DNA during treatment been established, and the optimal methodology remains unknown. We prospectively evaluated DNA levels and clinical response of 63 lymphoma patients. DNA was measured in paired serum, plasma, and cell samples at five predetermined time‐points taken prior, during and following treatment. Both cell‐free (c‐f) circulating EBV‐DNA (in EBV‐associated lymphoma) and nonspecific c‐f DNA levels (in all lymphomas) were elevated and discriminatory at presentation compared to healthy controls. Nonspecific c‐f DNA was significantly associated with baseline serum lactate dehydrogenase. Within EBV‐associated lymphomas at presentation, there was a strong correlation between specific and nonspecific circulating c‐f DNA (r = 0.9, P < 0.0001). However, only c‐f EBV‐DNA correlated with clinical/radiological response. In addition, c‐f EBV‐DNA, and not nonspecific c‐f DNA, provided an early marker of relapsed and refractory disease. Serum versus plasma, and single versus multiple‐copy EBV‐gene targets were equivalent. Lymphoma‐specific DNA is a disease response biomarker; however, nonspecific DNA reflected neither lymphoma‐specific DNA nor therapeutic response. Lymphoma disease response can be monitored by blood tests, but new lymphoma‐specific biomarkers need to be identified to broaden applicability. Am. J. Hematol. 2012. © 2011 Wiley Periodicals, Inc.
Biomass fuel use for cooking in Sri Lanka: Analysis of data from national demographic health surveys
Authors: Nandasena Sumal , Wickremasinghe Ananda R. , Sathiakumar Nalini 
Published: November 2011

AbstractBackgroundBiomass cooking fuel is the main source of indoor air pollution in the majority of households in the developing world. Sri Lanka is an island of about 20 million population with urban, rural, and estate population of 14.6%, 80.0%, and 5.4%, respectively. This study describes biomass fuel use for cooking in Sri Lanka.MethodsWe analyzed data from two national Demographic Health Surveys (2000 and 2007) to identify the use and determinants of cooking fuels in Sri Lankan households. The results are based on a sample of 8,169 households in 2000 and 19,862 households in 2007.ResultsWood was the principal cooking fuel used in 78.3% and 78.5% of households in 2000 and 2007, respectively. In 2007, 96.3% of estate sector households used firewood as compared to 84.2% in the rural and 34.6% in the urban sectors. Similar trends were noted in 2000 as well.ConclusionsThe shift from firewood to cleaner fuels in Sri Lanka is negligible from 2000 to 2007. Improving the quality of life of the population does not necessarily predict a shift towards the use of cleaner cooking fuels in Sri Lanka. Am. J. Ind. Med. 55:1122–1128, 2012. © 2011 Wiley Periodicals, Inc.