bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histomorphometric Evaluation of Bioceramic Molecular Impregnated and Dual Acid‐Etched Implant Surfaces in the Human Posterior Maxilla
Authors: Shibli Jamil Awad , Grassi Sauro , Piattelli Adriano , Pecora Gabriele E. , Ferrari Daniel S. , Onuma Tatiana , D'Avila Susana , Coelho Paulo G. , Barros Raquel , Iezzi Giovanna 
Published: April 2009

ABSTRACTBackground: Physical and bioceramic incorporation surface treatments at the nanometer scale showed higher means of bone‐to‐implant contact (BIC) and torque values compared with surface topography at the micrometer scale; however, the literature concerning the effect of nanometer scale parameters is sparse.Purpose: The aim of this study was to evaluate the influence of two different implant surfaces on the percentage bone‐to‐implant contact (BIC%) and bone osteocyte density in the human posterior maxilla after 2 months of unloaded healing.Materials and Methods: The implants utilized presented dual acid‐etched (DAE) surface and a bioceramic molecular impregnated treatment (Ossean®, Intra‐Lock International, Boca Raton, FL, USA) serving as control and test, respectively. Ten subjects (59 ± 9 years of age) received two implants (one of each surface) during conventional implant surgery in the posterior maxilla. After the non‐loaded period of 2 months, the implants and the surrounding tissue were removed by means of a trephine and were non‐decalcified processed for ground sectioning and analysis of BIC%, bone density in threaded area (BA%), and osteocyte index (Oi).Results: Two DAE implants were found to be clinically unstable at time of retrieval. Histometric evaluation showed significantly higher BIC% and Oi for the test compared to the control surface (p < .05), and that BA% was not significantly different between groups. Wilcoxon matched pairs test was used to compare the differences of histomorphometric variables between implant surfaces. The significance test was conducted at a 5% level of significance.Conclusion: The histological data suggest that the bioceramic molecular impregnated surface‐treated implants positively modulated bone healing at early implantation times compared to the DAE surface.
Accidental Displacement of Dental Implants into the Maxillary Sinus: A Report of Nine Cases
Authors: Ridaura‐Ruiz Lourdes , Figueiredo Rui , Guinot‐Moya Rosa , Piñera‐Penalva Manuel , Sanchez‐Garcés Maria Angeles , Valmaseda‐Castellón Eduard , Gay‐Escoda Cosme 
Published: April 2009

ABSTRACTPurpose: To report on the clinical, radiological, and anatomical features of patients suffering accidental displacement of dental implants into the maxillary sinus.Materials and Methods: A retrospective observational study of nine cases of dental implant displacement into the maxillary sinus was made. Data concerning patients' features, diagnostic criteria, and treatment performed were collected.Results: Mean patient age was 56.7 years, and men predominated (6 : 3). Implant displacement was diagnosed in all cases by clinical and radiological examination. In seven patients, the implant was surgically removed without complications. Only three patients reported sinus symptoms following displacement.Conclusions: The displacement of implants into the maxillary sinus is usually related with a poor surgical planning or inadequate surgical technique. Because of the anatomy and physiology of the posterior area of the maxilla, it is essential to ensure good primary stability in order to avoid this complication. If the implant migrates into the maxillary sinus, it should be removed in order to avoid sinus pathology.
Sexual Function in Men Treated for Testicular Cancer
Authors: Eberhard Jakob , Ståhl Olof , Cohn-Cedermark Gabriella , Cavallin-Ståhl Eva , Giwercman Yvonne , Rylander Lars , Eberhard-Gran Malin , Kvist Ulrik , Fugl-Meyer Kerstin S. , Giwercman Aleksander 
Published: April 2009

ABSTRACT

Introduction
Testicular germ cell cancer (TGCC) patients may be at risk of developing sexual dysfunction after treatment.

Aim
The aim of this study was to assess the prevalence of sexual dysfunctions in TGCC patients 3 to 5 years after treatment, and relate findings to biochemical hypogonadism, treatment intensity, and the expected prevalence in the Swedish male population.

Methods
A questionnaire study on 129 consecutive TGCC patients 3 to 5 years post-treatment was performed. Comparators were an age-matched nationally representative group of men (N = 916) included in a study on sexual life in Sweden.

Main Outcome Measures
Sexual functions (including erectile dysfunctional distress), time since last intercourse, sexual satisfaction, and experience of sexological treatment seeking were assessed using the same questions used in the epidemiological study on sexual life in Sweden. The findings in TGCC patients were correlated to biochemical signs of hypogonadism and type of oncological treatment: Surveillance, adjuvant chemotherapy, adjuvant radiotherapy, or standard doses of chemotherapy.

Results
A higher proportion of TGCC patients than comparators were likely to report low sexual desire (odds ratio [OR] 6.7 [95% confidence interval {CI} 2.1–21]) as well as erectile dysfunction (OR 3.8 [95% CI 1.4–10]). No significant differences were observed regarding erectile dysfunctional distress, change of desire over time, interest in sex, premature or delayed ejaculation, time since last intercourse, need for or receiving sexual advice, or sexual satisfaction. Hypogonadism did not predict erectile dysfunction (OR 1.1 [95% CI 0.26–4.5]) or low sexual desire (OR 1.2 [95% CI 0.11–14]). Treatment modality had no obvious impact on sexual function.

Conclusion
Men treated for testicular cancer had higher risk of having low sexual desire and erectile dysfunction 3 to 5 years after completion of therapy than comparators. These sexual dysfunctions were not significantly associated with treatment intensity or hypogonadism.
Hypogonadism, Decreased Sexual Desire, and Long-Term Depression in Middle-Aged Men
Authors: Hintikka Jukka , Niskanen Leo , Koivumaa-Honkanen Heli , Tolmunen Tommi , Honkalampi Kirsi , Lehto Soili M. , Viinamäki Heimo 
Published: April 2009

ABSTRACT

Introduction
In middle-aged men, the associations between long-term depressive symptoms and circulating testosterone levels are poorly known, although it is known that testosterone levels decrease with age.

Methods
A health questionnaire was mailed to a population-based sample from the National Population Register in 1998, 1999, and 2001. Based on their self-reported mental symptoms, a total of 116 men were selected for clinical examination in 2005. Half of them had high and the others low levels of adverse mental symptoms in all three previous follow-ups. A structured clinical interview for Diagnostic and Statistical Manual of Mental Disorders-IV was performed. Depressive symptoms were assessed with the Beck Depression Inventory (BDI) and the Hamilton Depression Rating Scale (HDRS). The Aging Males’ Symptoms scale was also compiled and testosterone levels were determined.

Results
In the entire study sample, serum free testosterone levels correlated negatively with both BDI and HDRS scores. In the hypogonadism group (based on free testosterone, 19.8% of the sample), clinically significant depression (BDI score ≥ 13) was more than three times as frequent as in the other men (34.8% vs. 10.4%), the odds ratio after multiple adjustments being 4.98 (95% confidence interval 1.66–14.95). A decrease in sexual desire was common in hypogonadism (36%). Nevertheless, it also associated with clinically significant depression, irrespective of free testosterone levels.

Discussion
Long-term and current depressive symptoms, a decreased sexual desire, and low serum free testosterone levels are associated in middle-aged men. Hypogonadism per se and as a cause of decreased sexual desire may be a contributory and possibly treatable factor underlying male depression.

Conclusions
The findings highlight the need for hormonal status assessment in middle-aged depressive men.
Metrics for Evaluation of Age-Related Changes in Erectile Capacity in a Rodent Model
Authors: Zhao Weixin , Sato Yoshikazu , Melman Arnold , Andersson Karl-Erik , Christ George 
Published: April 2009

ABSTRACTIntroductionStimulation of the cavernous nerve elicits increases in intracavernosal pressure (ICP) and visible penile erection (VPE) in rats. The observed penile erection can be characterized by the change in ICP and the ratio of ICP over blood pressure (BP; systemic blood pressure).AimWe evaluated correlations between ICP, BP, ICP/BP, and VPE, and the magnitude of the nerve stimulation required to elicit those responses in order to evaluate age-related changes in erectile function in a rodent model.MethodsNine young (3 months) and 10 old (18 months) rats were used. Under anesthesia cavernous nerve stimulation was performed at stimulation strengths ranging from 0.1 to 10 mA.Main Outcome MeasuresThe ICP, BP, ICP/BP, and VPE responses to cavernous nerve stimulation were quantified and compared.ResultsSignificant correlations were observed between ICP and ICP/BP in both young (r2 = 0.886) and old (r2 = 0.962) rats. If the ratio ICP/BP was taken as a metric of VPE and non-erection, then the threshold value for observing a VPE in the majority of animals was ≥0.5 in both young and old rats. However, higher current stimulation was required in the old than in the young animals to achieve erections. Moreover, both the maximal ICP and ICP/BP ratios achieved during erection were also lower in the old (85 ± 2 cmH2O and 0.6 ± 0.02, respectively) than young (106 ± 3 cmH2O and 0.75 ± 0.02, respectively) rats (P &lt; 0.0001).ConclusionOld rats without obvious comorbidities were capable of penile erections, but those erections were accompanied by reduced ICP responses to cavernous nerve stimulation, implying apparently reduced penile rigidity. Taken together our current observations indicate that ICP, ICP/BP, and VPE provide useful metrics/indices of erectile capacity/function, and, moreover, that improved understanding of the inter-relationships among these parameters provides a frame work for further exploration of the mechanistic basis for age-related erectile dysfunction.
Satisfaction (Sexual, Life, Relationship, and Mental Health) Is Associated Directly with Penile–Vaginal Intercourse, but Inversely with Other Sexual Behavior Frequencies
Authors: Brody Stuart , Costa Rui Miguel 
Published: April 2009

ABSTRACT

Introduction
Some sex therapists and educators assume that many sexual behaviors provide comparable sexual satisfaction. Evidence is required to determine whether sexual behaviors differ in their associations with both sexual satisfaction and satisfaction with other aspects of life.

Aims
To test the hypothesis that satisfaction with sex life, life in general, sexual partnership, and mental health correlates directly with frequency of penile–vaginal intercourse (PVI) and inversely with frequency of both masturbation and partnered sexual activity excluding PVI (noncoital sex).

Methods
A representative sample of 2,810 Swedes reported frequency of PVI, noncoital sex, and masturbation during the past 30 days, and degree of satisfaction with their sex life, life in general, partnership, and mental health.

Main Outcome Measures
Multivariate analyses (for the sexes separately and combined) considering the different satisfaction parameters as dependent variables, and the different types of sexual activities (and age) as putative predictors.

Results
For both sexes, multivariate analyses revealed that PVI frequency was directly associated with all satisfaction measures (part correlation = 0.50 with sexual satisfaction), masturbation frequency was independently inversely associated with almost all satisfaction measures, and noncoital sex frequencies independently inversely associated with some satisfaction measures (and uncorrelated with the rest). Age did not confound the results.

Conclusions
The results are consistent with evidence that specifically PVI frequency, rather than other sexual activities, is associated with sexual satisfaction, health, and well-being. Inverse associations between satisfaction and masturbation are not due simply to insufficient PVI.
A Prospective Study of Pelvic Floor Physical Therapy: Pain and Psychosexual Outcomes in Provoked Vestibulodynia
Authors: Goldfinger Corrie , Pukall Caroline F. , Gentilcore-Saulnier Evelyne , McLean Linda , Chamberlain Susan 
Published: April 2009

ABSTRACT

Introduction
Research suggests that increased tension in the pelvic floor muscles of women with provoked vestibulodynia (PVD, the most common form of chronic vulvar pain) may play an important role in maintaining and exacerbating their pain. However, no prospective studies of pelvic floor physical therapy (PFPT) for PVD have been carried out.

Aim
This study prospectively examined the effectiveness of a PFPT intervention in treating the pain and sexual and psychological components of PVD, and determined predictors of greater treatment success.

Methods
Thirteen women with PVD completed eight sessions of PFPT. Participants were assessed at pre- and post-treatment via gynecological examinations, vestibular pain threshold testing, structured interviews, and standardized questionnaires. A 3-month follow-up interview assessed any further changes.

Main Outcome Measures
Outcome measures included: vestibular pain thresholds, gynecological examination and intercourse pain ratings, sexual function and intercourse frequency, mental health, negative pain cognitions, and success rates.

Results
Following treatment, participants had significantly higher vestibular pain thresholds and significantly lower pain ratings during the gynecological examination. Participants reported significant reductions in pain intensity during intercourse and were able to engage in significantly more pain-free activities. Although overall sexual function significantly improved, various components of sexual function and frequency of intercourse did not. Participants’ mental health did not significantly improve; however, pain catastrophizing and pain-related anxiety significantly decreased. The treatment was considered to be successful for 10 of the 13 participants, and predictors of greater treatment success included greater reductions in helplessness and a longer period of time in treatment.

Conclusions
Results provide preliminary support for the effectiveness of PFPT in treating the pain of PVD, as well as some of the sexual and cognitive correlates of PVD. The results also indicate the need for large-scale, randomized studies of the effectiveness of PFPT in comparison and in conjunction with other treatment options.
PERCEPTION OF FRUITY AND VEGETATIVE AROMAS IN RED WINE
Authors: HEIN KAREN , EBELER SUSAN E. , HEYMANN HILDEGARDE 
Published: April 2009

ABSTRACT Red wine descriptive analyses often produce principal component analysis maps where the first dimension is a dichotomy of vegetative and fruity aromas. Whether the trend is due to actual flavor differences among wines, or is a function of masking of the component aromas has not been investigated. Descriptive analysis was performed on wines spiked with bell pepper, mint, corn, raspberry, strawberry and “berry” aromas as well as with combinations of these. A consensus trained panel evaluated wines in triplicate. Canonical variate analysis showed that wines spiked with either bell pepper or fruit were separated on the fruit/bell pepper continuum. Wines spiked with combinations of fruit and bell pepper had less intense in bell pepper aroma, even though the amount added did not change. These results indicate that a masking effect of vegetative aromas by fruit aromas occurred. PRACTICAL APPLICATIONSKnowing that bell pepper aromas, which are often not desired in Cabernet Sauvignon wines, are masked by fruity aromas allow winemakers to blend “out” the perceived vegetative aromas with wines that are more fruity. This could lead to better consumer acceptance of these wines.
The Study of Variation from Two Perspectives
Authors: Brunner Elizabeth Gentry 
Published: April 2009

AbstractThe field of sociolinguistics has a great deal in common with the field of forensic linguistics. One of their primary similarities is a focus on linguistic variation. Both fields analyze variation across groups of speakers, variation within speakers, variation between speakers, variation over time, and variation in perception. Sociolinguistic research can be directly applied to forensic linguistic issues. Model research projects are presented to demonstrate how to combine sociolinguistic and forensic linguistic goals and techniques into unified projects. This paper highlights how sociolinguists can advance the field of forensic linguistics in the United States.
Imaging in bronchopulmonary sequestration
Authors: Abbey P , Das CJ , Pangtey GS , Seith A , Dutta R , Kumar A 
Published: April 2009

SummaryBronchopulmonary sequestration is an uncommon pulmonary disorder characterized by an area of non‐functioning abnormal lung tissue, which receives its blood supply from a systemic artery and characteristically has no connection with the tracheobronchial tree. The abnormal lung tissue is located within the visceral pleura of a pulmonary lobe in the intralobar variety, whereas the extralobar form has its own visceral pleura. The venous drainage of the extralobar type is usually into the systemic veins, whereas the intralobar type drains into the pulmonary veins. Radiological imaging plays a vital role in establishing the diagnosis, and even more importantly, in providing to the clinician a vascular roadmap essential for surgical planning. We present here a review of bronchopulmonary sequestration and also discuss the role of various imaging methods in the early diagnosis and management of these cases.
Value of apparent diffusion coefficient measurement for discrimination of focal benign and malignant hepatic masses
Authors: Kilickesmez O , Bayramoglu S , Inci E , Cimilli T 
Published: April 2009

SummaryThe purpose of our study was to investigate the value of diffusion‐weighted magnetic resonance imaging (DW‐MRI) to discriminate benign and malignant focal lesions of the liver using parallel imaging technique. A total of 77 patients and 65 healthy controls were enrolled in the study. DW‐MRI was performed with b‐factors of 0, 500 and 1000 s/mm2, and the apparent diffusion coefficients (ADC) values of the normal liver and the lesions were calculated. The mean ADC value of the focal liver lesions were as follows: simple cysts (3.16 ± 0.18 × 10−3 mm2/s), hydatid cysts (2.58 ± 0.53 × 10−3 mm2/s), hemangiomas (1.97 ± 0.49 × 10−3 mm2/s), metastases (1.14 ± 0.41 × 10−3 mm2/s) and hepatocellular carcinomas (HCC) (1.15 ± 0.36 × 10−3 mm2/s). The mean ADC values of all the disease groups were statistically significant when compared with the mean ADC value of the normal liver (1.56 ± 0.14 × 10−3 mm2/s), (P < 0.01). There were also statistically significant differences among the ADC values of hemangiomas and HCC metastases (P < 0.01), and simple and hydatid cysts (P < 0.008). However, there was no statistically significant difference between HCC and metastases. The present study showed that ADC measurement has the potential to differentiate benign and malignant focal hepatic lesions. We propose to add DW sequence in the MR protocol for the detection and quantitative discrimination of hepatic pathologies.
Initial experience in 115 patients with the retrievable Cook Celect vena cava filter
Authors: Doody O , Given MF , Kavnoudias H , Street M , Thomson KR , Lyon SM 
Published: April 2009

SummaryThe aim of this study was to evaluate our experience with the retrievable Cook Celect inferior vena cava (IVC) filter (William Cook, Europe) with regard to insertion, efficiency, ease of retrieval, and any associated complications. A retrospective review was performed of 115 patients (41 female, 74 male, mean age 47.97 years) who underwent Cook Celect IVC filter insertion between December 2005 and October 2007. Filter insertion was successful in all patients. Of the 115 filters inserted, 57 have been successfully retrieved (49.6%) to date. The successful retrieval rate from attempted retrieval was 93.4%. The mean dwell time of successfully retrieved filters was 114.9 days (range 14–267 days). Failed retrievals were due to a thrombosed vena cava (n = 1) and endothelialisation of the filter (n = 3). In the failed retrieval group the mean implantation time was 142 days (range 78–211 days). While this is the first retrospective clinical study on the Cook Celect filter, results to date are promising. We demonstrated an efficacious filter with a high successful retrieval rate of 93.4% and a low complication rate. The filter was assessed with extended dwell times (range 14–267 days). Failed retrieval secondary to hook endothelialisation continues to be an issue with this filter. We recognize that a limitation of our study was the lack of systematic follow‐up for clinically silent complications. Further studies to evaluate longer term outcomes and effectiveness of this filter are warranted.
Prognostic significance of several histological features in intermediate and high‐risk endometrial cancer patients treated with curative intent using surgery and adjuvant radiotherapy
Authors: Narayan K , Rejeki V , Herschtal A , Bernshaw D , Quinn M , Jobling T , Allen D 
Published: April 2009

SummaryThe purpose of the present study was to explore the prognostic significance of several histological features with respect to lymph node metastasis, failure‐free survival (FFS), and overall survival (OS) in intermediate and high‐risk endometrial cancer patients treated with curative intent. One hundred and eighty patients with endometrial cancer were treated with hysterectomy with or without lymphadenectomy and received external beam radiotherapy (EBRT). The mean follow‐up period was 4.25 years (range 0.44–10.45 years). In multifactor analysis, fractional myometrial invasion (MI) (P = 0.047), histology (P < 0.001) and lymph‐vascular space invasion (LVSI) (P = 0.025) were significant predictors for FFS when nodal status was not included. When lymph node status was known, histology (P = 0.007) and LVSI (P = 0.014) remained significant factors for FFS. For OS, histology (P < 0.001) and fractional MI (P = 0.004) were the significant factors. Lymph node status could be predicted by tumour grading (P = 0.016) and absolute MI (P = 0.002). Histology type and the presence of LVSI were the most important prognostic factors in high‐risk endometrial cancer patients treated by surgery and postoperative radiotherapy. Absolute MI and tumour grading were useful predictors of nodal spread.
Influence of CT contrast agent on dose calculation of intensity modulated radiation therapy plan for nasopharyngeal carcinoma
Authors: Lee FK‐H , Chan CC‐L , Law C‐K 
Published: April 2009

SummaryContrast enhanced computed tomography (CECT) has been used for delineation of treatment target in radiotherapy. The different Hounsfield unit due to the injected contrast agent may affect radiation dose calculation. We investigated this effect on intensity modulated radiotherapy (IMRT) of nasopharyngeal carcinoma (NPC). Dose distributions of 15 IMRT plans were recalculated on CECT. Dose statistics for organs at risk (OAR) and treatment targets were recorded for the plain CT‐calculated and CECT‐calculated plans. Statistical significance of the differences was evaluated. Correlations were also tested, among magnitude of calculated dose difference, tumor size and level of enhancement contrast. Differences in nodal mean/median dose were statistically significant, but small (approximately 0.15 Gy for a 66 Gy prescription). In the vicinity of the carotid arteries, the difference in calculated dose was also statistically significant, but only with a mean of approximately 0.2 Gy. We did not observe any significant correlation between the difference in the calculated dose and the tumor size or level of enhancement. The results implied that the calculated dose difference was clinically insignificant and may be acceptable for IMRT planning.