bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: H2O2 in CO2: Sustainable Production and Green Reactions
Authors: Hancu Dan , Green Jordan , Beckman Eric J. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sulfur in Homogeneous Catalysis.
Authors: Kalck Philippe , Serp Philippe 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Throughput Approaches to Homogeneous Catalysis.
Authors: Murphy Vince , Turner Howard W. , Weskamp Thomas 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: TAML Oxidant Activators: A New Approach to the Activation of Hydrogen Peroxide for Environmentally Significant Problems
Authors: Collins Terrence J. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Development of a New Concept: The Role of Oxygen Transients, Defect and Precursor States in Surface Reactions
Authors: Carley A. F. , Davies P. R. , Roberts M. W. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Real‐Time Electrochemical Monitoring: Toward Green Analytical Chemistry
Authors: Wang Joseph 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solid‐Phase Synthesis of Biologically Important Glycopeptides
Authors: Bezay Nicole , Kunz Horst 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Supports for Solid‐Phase Synthesis
Authors: Fromont Christophe , Pomel Vincent , Bradley Mark 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Developments in Luminescence and Display Materials over the Last 100 Years as Reflected in Electrochemical Society Publications
Authors: Chen Reuven , Lockwood David J. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Calixarenes as Alkali Metal Ions Receptors
Authors: Sliwa Wanda 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Resolution and Cross‐Polarization Magic Angle Spinning NMR Studies of Tricarbonylchromium Complexes with Polycyclic Aromatic Ligands
Authors: Oprunenko Yu. F. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vibrational Optical Activity Theory
Authors: Nafie Laurence A. , Freedman Teresa B. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Solid‐Phase Microextraction to Chemical Analysis of Live Biological Samples
Authors: Augusto Fabio , Luiz Pires Valente Antonio 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Shifts in Amino Acids, Peptides, and Proteins: From Quantum Chemistry to Drug Design
Authors: Oldfield Eric 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and Orientation of Ligands Bound to Membrane Proteins Are Reflected by Residual Dipolar Couplings in Solution NMR Measurements
Authors: Koenig Bernd W. 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dynamics in Rhodopsin
Authors: Klein‐Seetharaman Judith 
Published: May 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PX4+, P2X5+, and P5X2+ (X: Br, I) Salts of the Superweak Al(OR)4‐ Anion [R: C(CF3)3].
Authors: Gonsior Marcin , Krossing Ingo , Mueller Lutz , Raabe Ines , Jansen Martin , van Wuellen Leo 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Syntheses, Crystal Structures, and Reactivity of [enH]4[Sn2Se6]×en, [enH]4[Sn2Te6]×en and [enH]4[Sn2S6]: Known Anions within Novel Coordination Spheres Obtained by Novel Synthesis Routes.
Authors: Dehnen Stefanie , Zimmermann Christian 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Bismuth Polyanions in Solution: Synthesis and Structural Characterization of (2,2,2‐Crypt‐A)2Bi4 (A: K, Rb) and the Formation of the Laves Phases ABi2 (A: K, Rb, Cs) from Solution.
Authors: Kuznetsov Alexei N. , Faessler Thomas F. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Crystal Structure of the Complexes [(n‐Bu)4N]2 [{(THF)Cl4ReN}2PdCl2], [Ph4P]2 [(THF)Cl4ReN‐PdCl(μ‐Cl)]2 and [(η‐Bu)4N]2[Pd3Cl8].
Authors: Schwarz Simon , Straehle Joachim , Weisser Ulrike 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Strategy for the Stereoselective Synthesis of Unsymmetric Atropisomeric Ligands: Preparation of NAPhePHOS, a New Biaryl Diphosphine.
Authors: Michaud Guillaume , Bulliard Michel , Ricard Louis , Genet Jean‐Pierre , Marinetti Angela 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereoselective Formation of Optically Active 2‐Oxy‐1,3‐oxazolidin‐4‐ones and an Efficient Synthesis of Optically Active Secondary 2‐Pyrrolidones.
Authors: Omata Yoji , Kakehi Akikazu , Shirai Masashi , Kamimura Akio 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereo‐ and Regioselective Functionalization of Alkynes Catalyzed by Platinum(IV) and Palladium(II) Complexes in the System I‐—I3‐—H2O/MeOH.
Authors: Ananikov V. P. , Mitchenko S. A. , Beletskaya I. P. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Amine‐Catalyzed Direct Self Diels—Alder Reactions of α,β‐Unsaturated Ketones in Water: Synthesis of Pro‐Chiral Cyclohexanones.
Authors: Ramachary D. B. , Chowdari Naidu S. , Barbas III Carlos F. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Copper Phosphoramidite Catalyzed Enantioselective Ring‐Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol.
Authors: Bertozzi Fabio , Pineschi Mauro , Macchia Franco , Arnold Leggy A. , Minnaard Adriaan J. , Feringa Ben L. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Selective Enzymatic Epoxidation of Dienes: Generation of Functional Enantiomerically Enriched Dieno Monoepoxy Monomers.
Authors: Hu Shanghui , Gupta Pankaj , Prasad Ashok K. , Gross Richard A. , Parmar Virinder S. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Unprecedented Stability of Vinyloxy Group under Conditions of Acid Hydrolysis: Synthesis of 1‐[(2‐Vinyloxy)ethyl]‐1,5‐dihydro‐2H‐pyrrol‐2‐ones.
Authors: Nedolya N. A. , Brandsma L. , Tolmachev S. V. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Properties of 2‐(2‐Furyl)‐ and 2‐(2‐Thienyl)‐1‐methylphenanthro[9,10‐d]imidazoles.
Authors: Pechkin A. A. , El'chaninov M. M. , Stoyanov V. M. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Antimicrobial Activity of Some New Hydrazones of 4‐Fluorobenzoic Acid Hydrazide and 3‐Acetyl‐2,5‐disubstituted‐1,3,4‐oxadiazolines.
Authors: Rollas Sevim , Gulerman Nehir , Erdeniz Habibe 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Biosynthesis Inspired Diels—Alder Route to Pyridines: Synthesis of the 2,3‐Dithiazolylpyridine Core of the Thiopeptide Antibiotics.
Authors: Moody Christopher J. , Hughes Rachael A. , Thompson Stewart P. , Alcaraz Lilian 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Multicomponent Domino Process to Oxa‐Bridged Polyheterocycles and Pyrrolopyridines, Structural Diversity Derived from Work‐up Procedure.
Authors: Gamez‐Montano Rocio , Gonzalez‐Zamora Eduardo , Potier Pierre , Zhu Jieping 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Pyrimidium Ylides. Part 11. Regiochemistry of the 1,3‐Dipolar Cycloaddition of 4‐(2‐Furyl)‐ and 4‐(2‐Thienyl)‐pyrimidinium Ylides to Ethyl Propiolate.
Authors: Iuhas Paula Cristina , Georgescu Florentina , Georgescu Emilian , Draghici Constantin , Caproiu Miron T. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Biological Activity of 5‐Alkyl‐6‐(alkylsulfanyl)‐ or 5‐Alkyl‐6‐(arylsulfanyl)pyrazine‐2‐carboxamides and Corresponding Thioamides.
Authors: Krinkova Jana , Dolezal Martin , Hartl Jiri , Buchta Vladimir , Pour Milan 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Pharmacological Properties of 3‐Amino‐1,2‐dihydro‐3H‐1,4‐benzodiazepin‐2‐one Derivatives.
Authors: Andronati K. S. , Kostenko E. A. , Karaseva T. L. , Andronati S. A. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Pharmacological Properties of Phosphorylacetohydrazones and Phosphorylacetohydrazines.
Authors: Tarasova R. I. , Voskresenskaya O. V. , Semina I. I. , Kurmysheva T. V. , Balashov V. P. , Moskva V. V. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Convenient Synthesis of N‐Fluorenylmethoxycarbonyl‐N‐methyl‐L‐cysteine Derivatives [Fmoc, Me‐Cys(R)‐OH].
Authors: Liu Jia‐Feng , Tang Xiao‐Xia , Jiang Biao 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Characterization of Nucleoside Derivatives, N‐(Benzoyl)‐N‐(deoxyguanosin‐8‐yl)‐4‐aminobiphenyl and N‐(2′‐Deoxyguanosin‐8‐yl)‐4‐aminobiphenyl via α‐Phenyl‐N‐(4‐biphenyl)nitrone.
Authors: Mallesha H. , Kumar K. R. Ravi , Rangappa K. S. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Prostanoids. Part 84. Synthons for New Halochlorvulones II from 6,7‐Dichloro‐1,4‐dioxospiro[4.4]non‐6‐en‐8‐one.
Authors: Ivanova N. A. , Shainurova A. M. , Khusainova A. A. , Shitikova O. V. , Akhmetvaleev R. R. , Miftakhov M. S. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Total Synthesis of Pederin, a Potent Insect Toxin: The Efficient Synthesis of the Right Half, (+)‐Benzoylpedamide.
Authors: Takemura Takahiro , Nishii Yoshinori , Takahashi Shunya , Kobayashi Jun'ichi , Nakata Tadashi 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Other Physical Methods [For Studying Carbohydrates]
Authors: Ferrier R. J. , Blattner R. , Field R. A. , Furneaux R. H. , Gardiner J. M. , Hoberg J. O. , Kartha K. P. R. , Tilbrook D. M. G. , Tyler P. C. , Wightman R. H. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Overall View of the Use of Chiral Platinum(II) Complexes as Chiral Derivatizing Agents (CDAs) for the Enantiodiscrimination of Unsaturated Compounds by195Pt NMR
Authors: Uccello‐Barretta Gloria , Bernardini Raffaella , Balzano Federica , Salvadori Piero 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Replacement of Imine Fragment in the Ring of 2,6‐Disubstituted 1,4,3,5‐Oxathiadiazine‐4,4‐dioxides in Reaction with Cyano‐Containing Compounds.
Authors: Utkina E. N. , Michurin A. A. , Shishulina A. V. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Highly Enantioselective and Practical Cinchona‐Derived Phase‐Transfer Catalysts for the Synthesis of α‐Amino Acids.
Authors: Park Hyeung‐geun , Jeong Byeong‐Seon , Yoo Mi‐Sook , Lee Jeong‐Hee , Park Mi‐kyoung , Lee Yeon‐Ju , Kim Mi‐Jeong , Jew Sang‐sup 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of [(2S,3S,4R)‐3,4‐Dihydroxypyrrolidin‐2‐yl]‐5‐methylfuran‐4‐carboxylic Acid Derivatives: New Leads as Selective β‐Galactosidase Inhibitors.
Authors: Moreno‐Vargas Antonio J. , Demange Raynald , Fuentes Jose , Robina Inmaculada , Vogel Pierre 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Design and Synthesis of Conformationally Restricted Eight‐Membered Ring Diketones as Potential Serine Protease Inhibitors.
Authors: Pearson Neil D. , Eggleston Drake S. , Haltiwanger R. Curtis , Hibbs Martin , Laver Alison J. , Kaura Arun C. 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Syntheses of the D‐, E‐, F‐, and I‐Ring Parts of Ciguatoxin by a Common Strategy Starting from Tri‐O‐acetyl‐D‐glucal.
Authors: Fujiwara Kenshu , Koyama Yasuhito , Doi Eriko , Shimawaki Ken , Ohtaniuchi Yuko , Takemura Atsushi , Souma Shin‐ichiro , Murai Akio 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
The Nucleophilic 5‐endo‐trig‐Cyclization of 1,1‐Difluoro‐1‐alkenes: Ring‐Fluorinated Hetero‐ and Carbocycle Synthesis and Remarkable Effect of the Vinylic Fluorines on the Disfavored Process
Authors: Ichikawa Junji , Wada Yukinori , Fujiwara Masaki , Sakoda Kotaro 
Published: May 2010

AbstractFor Abstract see ChemInform Abstract in Full Text.
Involvement of E2F1 transcriptional activity in cadmium‐induced cell‐cycle arrest at G1 in human lung fibroblasts
Authors: Choi You‐Jin , Yin Hu‐Quan , Suh Hyo‐Ryung , Lee Young‐Ju , Park So‐Ra , Lee Byung‐Hoon 
Published: May 2010

AbstractHuman cadmium (Cd) exposure is associated with cancers of the lung and kidney. Using cDNA microarray analysis, we have recently reported that the expression of E2F1 is reduced by Cd in human lung fibroblasts, indicating the possibility of G1‐phase arrest. To test this hypothesis, we investigated the effects of Cd on the cyclin‐dependent kinase (CDK2) and retinoblastoma protein (Rb) regulatory pathways in WI38 human lung fibroblasts. We demonstrate here that G1‐phase accumulation was induced by Cd in WI38 (wild‐type for p53 and Rb), but not in the SV40 large T antigen‐transformed variant WI38‐VA13 (p53‐ and Rb‐defective). Cd‐induced cell‐cycle arrest was associated with a decrease in CDK2 protein and with increase in p21 expression and p53 phosphorylation. Cd treatment caused a distinct increase in the formation of p21‐cyclin E‐CDK2 complex, as revealed by immunoprecipitation. The level of Rb‐E2F1 complexes was increased, and the translocation of E2F1 to the nucleus was decreased by Cd treatment. Consequently, the transcriptional activity of E2F1 and the expression of the E2F1 target genes were also decreased by Cd. These results clearly demonstrate that Cd‐mediated G1 arrest in WI38 cells is associated with the suppression of Rb phosphorylation and with the inhibition of E2F1 transcriptional activity. Environ. Mol. Mutagen. 52:145–152, 2011. © 2010 Wiley‐Liss, Inc.
Kynurenine inhibits chondrocyte proliferation and is increased in synovial fluid of patients with septic arthritis
Authors: Lögters Tim T. , Laryea Maurice D. , Jäger Marcus , Schädel‐Höpfner Michael , Windolf Joachim , Flohé Sascha , Altrichter Jens , Scholz Martin , Paunel‐Görgülü Adnana N. 
Published: May 2010

AbstractKynurenine, the major degradation product of tryptophan has been shown to directly damage various tissues. Its potential contribution to septic arthritis is unknown. In this study, we analyzed the putative diagnostic value of kynurenine for bacterial joint infection and its potential harmful effects on cartilage. In a prospective study 41 patients with a joint effusion who had undergone arthrocentesis were included. Tryptophan and kynurenine levels from synovial fluid were quantified by HPLC. Diagnostic value of kynurenine was evaluated and its effects on the proliferation of the chondrocyte cell line ATDC5 were determined. Synovial fluid kynurenine values from patients with septic arthritis (4.1 ± 0.8 µmol/L, n = 9) were significantly increased compared to patients with non‐infectious inflammatory arthropathy (1.8 ± 0.2 µmol/L, n = 17) or osteoarthritis (1.2 ± 0.1 µmol/L, n = 15, p < 0.01). At a cut‐off value of 2.28 µmol/L kynurenine had a sensitivity of 0.89 and a specificity of 0.87. Further, kynurenine inhibited chondrocyte (ATDC5) cell proliferation in a dose‐dependent manner. Septic arthritis is associated with significantly increased values of synovial kynurenine. Furthermore kynurenine inhibits proliferation of chondrocytes, which strongly suggests a pathophysiological effect of kynurenine on cartilage in inflammatory arthropathies. © 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:1490–1496, 2010
A novel MSC‐seeded triphasic construct for the repair of osteochondral defects
Authors: Marquass B. , Somerson J.S. , Hepp P. , Aigner T. , Schwan S. , Bader A. , Josten C. , Zscharnack M. , Schulz R.M. 
Published: May 2010

AbstractMesenchymal stem cells (MSC) are increasingly replacing chondrocytes in tissue engineering based research for treatment of osteochondral defects. The aim of this work was to determine whether repair of critical‐size chronic osteochondral defects in an ovine model using MSC‐seeded triphasic constructs would show results comparable to osteochondral autografting (OATS). Triphasic implants were engineered using a beta‐tricalcium phosphate osseous phase, an intermediate activated plasma phase, and a collagen I hydrogel chondral phase. Autologous MSCs were used to seed the implants, with chondrogenic predifferentiation of the cells used in the cartilage phase. Osteochondral defects of 4.0 mm diameter were created bilaterally in ovine knees (n = 10). Six weeks later, half of the lesions were treated with OATS and half with triphasic constructs. The knees were dissected at 6 or 12 months. With the chosen study design we were not able to demonstrate significant differences between the histological scores of both groups. Subcategory analysis of O'Driscoll scores showed superior cartilage bonding in the 6‐month triphasic group compared to the autograft group. The 12‐month autograft group showed superior cartilage matrix morphology compared to the 12‐month triphasic group. Macroscopic and biomechanical analysis showed no significant differences at 12 months. Autologous MSC‐seeded triphasic implants showed comparable repair quality to osteochondral autografts in terms of histology and biomechanical testing. © 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:1586–1599, 2010
A half mode substrate integrated epsilon near zero resonator and notch filter
Authors: Kataria Tejinder Kaur , Corona‐Chavez Alonso , Murthy D.V. B. 
Published: May 2010

AbstractIn this article a miniaturized, half‐mode substrate integrated epsilon near zero (ENZ) tunnel is presented. This structure supports a reflection‐less transmission at a single frequency when epsilon is near zero. Moreover, this tunnel is connected to a CRLH filter in a decoupling mode to reject unwanted frequencies. Design methodology, simulation, and measurement results of this structure are presented. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 1707–1709, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.25297