bluuebunny/crossref_metadata_2025_split huggingface dataset:
Midwife-led psycho-education intervention to reduce childbirth fear: a quasi-experimental study
Authors: Abadi Marzoni Zahra , Bakouei Fatemeh , Aghajani Delavar Molood , Hamidia Angela , Sepidarkish Mahdi 
Published: April 2024

Abstract
This quasi-experimental study aimed to assess the impact of a midwife-led psycho-education intervention on reducing fear of childbirth (FOC) and perceived stress (PS) in pregnant women. The present study involved 96 pregnant women. The intervention group received three 30–45 min telephone sessions using ‘BELIEF’ (Birth Emotion-Looking to Improve Expectant Fear) psycho-education approach. The outcomes were assessed using questionnaires on childbirth attitudes and PS. Data analysis was performed using Stata version 17. In the intervention group, the mean score for FOC decreased from 39.41 ± 7.02 to 29.91 ± 5.60 (9.5; 24.1%). The mean difference (MD) of 28.22% was statistically significant (adjusted MD: −10.51, 95% CI: −11.60, −9.41, P &lt; 0.001). In the intervention group, mean scores for PS decreased from 22.77 ± 6.94 to 18.23 ± 5.69 (4.54; 19.93%). In the control group, scores increased from 22.68 ± 6.76 to 24.82 ± 6.58 (2.14; 9.43%). The 29.36% MD was statistically significant (aMD: −6.95, 95% CI: −8.73, −5.18, P &lt; 0.001). The findings of this study indicate that the midwife-led psycho-education intervention, utilizing the ‘BELIEF’ protocol over the telephone, has a significant effect on reducing FOC and PS, as well as increasing the preference for vaginal birth.
Medication reuse programs: a narrative review of the literature
Authors: Watts Samuel , Coutsouvelis John , Wickens Joanne , Poole Susan , Percival Mia , Zalcberg John R 
Published: April 2024

Abstract
A proportion of returned medications may potentially meet quality standards to be reused safely. In Australia, there is no regulatory guidance available to facilitate such medication reuse. This narrative review aimed to identify and review international literature describing medication reuse programs to provide insight into their implementation and potential barriers. Using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) -based guidelines, a literature search was conducted in Medline, Scopus, and Embase using key words such as ‘medication’ and ‘reuse’ to identify relevant articles. Two reviewers ascertained eligibility for inclusion. Inclusion criteria included English language and publication after 2010. From the articles selected, identified international medication reuse programs and relevant regulatory aspects were summarized. Details, both regulatory and operational, for the specific medication reuse programs, described in the selected articles was further explored via a grey literature search. Of the 1973 identified articles, 84 were assessed for eligibility and 17 were included in this review. Of these, 14 described scenarios where medication reuse is prohibited, 2 studies described programs allowing the reuse of medication and 1 study did not discuss whether reuse was prohibited or not. From these primary articles, secondary citations were identified, with eight from gray literature. Barriers to medication reuse included exposure to environmental extremes during storage, physical appearance, evidence of tampering, safety, and efficacy concerns for the returned medication. Programs that exist globally have overcome these barriers. Several programs that provide safe and effective reuse of medications were identified and described. The findings described in this review should be used to inform frameworks for legislative, regulatory, and professional practice change for medication reuse. Measures implemented in the UK’s pandemic response to safely reuse medications in the nursing home and hospice settings and European medication donation programs should be further investigated. The concept of medication reuse is not novel and should be considered for the Australian setting.
Skeletal stem and progenitor cells in bone development and repair
Authors: Trompet Dana , Melis Seppe , Chagin Andrei S , Maes Christa 
Published: April 2024

Abstract
Bone development, growth, and repair are complex processes involving various cell types and interactions, with central roles played by skeletal stem and progenitor cells. Recent research brought new insights into the skeletal precursor populations that mediate intramembranous and endochondral bone development. Later in life, many of the cellular and molecular mechanisms determining development are reactivated upon fracture, with powerful trauma-induced signaling cues triggering a variety of postnatal skeletal stem/progenitor cells (SSPCs) residing near the bone defect. Interestingly, in this injury context, the current evidence suggests that the fates of both SSPCs and differentiated skeletal cells can be considerably flexible and dynamic, and that multiple cell sources can be activated to operate as functional progenitors generating chondrocytes and/or osteoblasts. The combined implementation of in vivo lineage tracing, cell surface marker-based cell selection, single-cell molecular analyses, and high-resolution in situ imaging has strongly improved our insights into the diversity and roles of developmental and reparative stem/progenitor subsets, while also unveiling the complexity of their dynamics, hierarchies, and relationships. Albeit incompletely understood at present, findings supporting lineage flexibility and possibly plasticity among sources of osteogenic cells challenge the classical dogma of a single primitive, self-renewing, multipotent stem cell driving bone tissue formation and regeneration from the apex of a hierarchical and strictly unidirectional differentiation tree. We here review the state of the field and the newest discoveries in the origin, identity, and fates of skeletal progenitor cells during bone development and growth, discuss the contributions of adult SSPC populations to fracture repair, and reflect on the dynamism and relationships among skeletal precursors and differentiated cell lineages. Further research directed at unraveling the heterogeneity and capacities of SSPCs, as well as the regulatory cues determining their fate and functioning, will offer vital new options for clinical translation toward compromised fracture healing and bone regenerative medicine.
Divergences in the recent case-law of the General Court of the European Union in the field of IP
Authors: Dimitrakopoulos Ioannis 
Published: April 2024

Abstract
The purpose of the present article is to identify certain important issues in relation to which there have been divergences in the recent case-law of the General Court of the EU in the field of IP law and to examine the way the EU judicature has dealt with them. It is structured as follows. Its introductory part presents succinctly the main reasons for inconsistencies in the case-law of the General Court in the field of IP law and the existing mechanisms aimed at preventing, eliminating or minimizing them. Its main part examines the following four questions of EU IP procedural and substantive law, reflecting diverging opinions of the General Court: (i) admissibility of an intervention before the General Court submitted by the other party to the proceedings before the Board of Appeal of the European Union Intellectual Property Office (EUIPO); (ii) admissibility of evidence presented for the first time before the General Court in proceedings concerning EU trade marks; (iii) effect of the termination of protection of earlier rights while proceedings are pending before EUIPO; and (iv) likelihood of confusion in the context of the comparison of goods in cases involving alcoholic and non-alcoholic beverages. The article concludes by stressing that, while the occurrence of divergences in the case-law of the General Court may be unavoidable, swift detection of the existence and the exact content of such issues is an important step towards resolving them effectively, in the interest of legal certainty and equality in the application of law.
Statewide surveillance of Ixodes scapularis (Acari: Ixodidae) for the presence of the human pathogen Borrelia miyamotoi (Spirochaetales: Spirochaetaceae), a relapsing fever spirochete in Pennsylvania, USA, 2019–2020
Authors: Coder Brooke L , Price Keith J , Tewari Deepanker , Witmier Bryn J , Chapman Holly A , Chroscinski Michael S , Long Jason , Livengood Julia L , Boyer Christian N 
Published: April 2024

Abstract
Borrelia miyamotoi disease is an emerging tick-borne human illness in the United States caused by Borrelia miyamotoi (Spirochaetales: Spirochaetaceae) bacterium. With Pennsylvania reporting thousands of tick-borne disease cases annually, determining the minimum infection rate (MIR) of B. miyamotoi in Ixodes scapularis (Say, Acari: Ixodidae) adults within Pennsylvania is of utmost importance. Active surveillance was performed from October 2019 to April 2020 to collect a minimum of 50 I. scapularis ticks from every county within Pennsylvania and then screened for B. miyamotoi via qPCR. Ticks were collected from all 67 counties with the majority of those being adult I. scapularis. Additional ticks collected were Dermacentor albipictus (Packard, Acari: Ixodidae), Haemaphysalis longicornis (Neumann, Acari: Ixodidae), and immature I. scapularis. Adult I. scapularis were pooled and tested for B. miyamotoi. MIR for positive B. miyamotoi pools and density of infected adult I. scapularis varied by county, with positive pools from 38 Pennsylvania counties. This is the first statewide evaluation of B. miyamotoi in Pennsylvania in questing adult I. scapularis. These prevalence and distribution data will aid health care practitioners within the state of Pennsylvania and the northeast United States to understand potential risk and bring awareness to the lesser known human Borrelia illness, Borrelia miyamotoi disease.
A Rare Case of Metastatic Poorly Differentiated Neuroendocrine Tumor Arising From the Sigmoid Colon in an Active Duty Service Member
Authors: Arnold Casey , Hourigan Erin K , Shudee Wu , Jilinksi Sherry , Bush Allison , Feinman Amber , Harvey Amie 
Published: April 2024

ABSTRACT
Neuroendocrine tumors (NET) are rare malignancies that contain neural and endocrine cells with a median age of diagnosis of 63 years. NETs are typically located in the gastrointestinal (GI) tract, the pancreas, or the lungs. Within the GI tract, the most common locations for NETs are the small bowel, appendix, or rectum. They are often asymptomatic and found incidentally on imaging or during procedures. NETs arising from the left side of the colon are very uncommon. While most NETs are well-differentiated by histology and are slow growing, 7% are poorly differentiated and usually progress rapidly. While rare, it is vital to be vigilant for this reason We present such a case of poorly differentiated metastatic NET of the sigmoid colon in a young active duty service member.
Simulating biosignatures from pre-oxygen photosynthesizing life on TRAPPIST-1e
Authors: Eager-Nash Jake K , Daines Stuart J , McDermott James W , Andrews Peter , Grain Lucy A , Bishop James , Rogers Aaron A , Smith Jack W G , Khalek Chadiga , Boxer Thomas J , Mak Mei Ting , Ridgway Robert J , Hébrard Eric , Lambert F Hugo , Lenton Timothy M , Mayne Nathan J 
Published: April 2024

ABSTRACT
In order to assess observational evidence for potential atmospheric biosignatures on exoplanets, it will be essential to test whether spectral fingerprints from multiple gases can be explained by abiotic or biotic-only processes. Here, we develop and apply a coupled 1D atmosphere-ocean-ecosystem model to understand how primitive biospheres, which exploit abiotic sources of H$_2$, CO, and O$_2$, could influence the atmospheric composition of rocky terrestrial exoplanets. We apply this to the Earth at 3.8 Ga and to TRAPPIST-1e. We focus on metabolisms that evolved before the evolution of oxygenic photosynthesis, which consume H$_2$ and CO and produce potentially detectable levels of CH$_4$. O$_2$-consuming metabolisms are also considered for TRAPPIST-1e, as abiotic O$_2$ production is predicted on M-dwarf orbiting planets. We show that these biospheres can lead to high levels of surface O$_2$ (approximately 1–5 per cent) as a result of CO consumption, which could allow high O$_2$ scenarios, by removing the main loss mechanisms of atomic oxygen. Increasing stratospheric temperatures, which increases atmospheric OH can reduce the likelihood of such a state forming. O$_2$-consuming metabolisms could also lower O$_2$ levels to around 10 ppm and support a productive biosphere at low reductant inputs. Using predicted transmission spectral features from CH$_4$, CO, O$_2$/O$_3$, and CO$_2$ across the hypothesis space for tectonic reductant input, we show that biotically produced CH$_4$ may only be detectable at high reductant inputs. CO is also likely to be a dominant feature in transmission spectra for planets orbiting M-dwarfs, which could reduce the confidence in any potential biosignature observations linked to these biospheres.
3D hydrodynamic simulations of massive main-sequence stars – II. Convective excitation and spectra of internal gravity waves
Authors: Thompson William , Herwig Falk , Woodward Paul R , Mao Huaqing , Denissenkov Pavel , Bowman Dominic M , Blouin Simon 
Published: April 2024

ABSTRACT
Recent photometric observations of massive stars have identified a low-frequency power excess which appears as stochastic low-frequency variability in light-curve observations. We present the oscillation properties of high-resolution hydrodynamic simulations of a $25\,\,{\rm{M}_\odot }$ star performed with the PPMstar code. The model star has a convective core mass of $\approx 12\,\,{\rm{M}_\odot }$ and approximately half of the envelope simulated. From this simulation, we extract light curves from several directions, average them over each hemisphere, and process them as if they were real photometric observations. We show how core convection excites waves with a similar frequency as the convective time-scale in addition to significant power across a forest of low and high angular degree l modes. We find that the coherence of these modes is relatively low as a result of their stochastic excitation by core convection, with lifetimes of the order of 10s of days. Thanks to the still significant power at higher l and this relatively low coherence, we find that integrating over a hemisphere produces a power spectrum that still contains measurable power up to the Brunt–Väisälä frequency. These power spectra extracted from the stable envelope are qualitatively similar to observations, with the same order of magnitude yet lower characteristic frequency. This work further shows the potential of long-duration, high-resolution hydrodynamic simulations for connecting asteroseismic observations to the structure and dynamics of core convection and the convective boundary.
SwissDock 2024: major enhancements for small-molecule docking with Attracting Cavities and AutoDock Vina
Authors: Bugnon Marine , Röhrig Ute F , Goullieux Mathilde , Perez Marta A S , Daina Antoine , Michielin Olivier , Zoete Vincent 
Published: April 2024

Abstract
Drug discovery aims to identify potential therapeutic compounds capable of modulating the activity of specific biological targets. Molecular docking can efficiently support this process by predicting binding interactions between small molecules and macromolecular targets and potentially accelerating screening campaigns. SwissDock is a computational tool released in 2011 as part of the SwissDrugDesign project, providing a free web-based service for small-molecule docking after automatized preparation of ligands and targets. Here, we present the latest version of SwissDock, in which EADock DSS has been replaced by two state-of-the-art docking programs, i.e. Attracting Cavities and AutoDock Vina. AutoDock Vina provides faster docking predictions, while Attracting Cavities offers more accurate results. Ligands can be imported in various ways, including as files, SMILES notation or molecular sketches. Targets can be imported as PDB files or identified by their PDB ID. In addition, advanced search options are available both for ligands and targets, giving users automatized access to widely-used databases. The web interface has been completely redesigned for interactive submission and analysis of docking results. Moreover, we developed a user-friendly command-line access which, in addition to all options of the web site, also enables covalent ligand docking with Attracting Cavities. The new version of SwissDock is freely available at https://www.swissdock.ch/.
Developing a Vape Shop-Based Smoking Cessation Intervention: A Delphi Study
Authors: Langley Tessa , Young Emily , Hunter Abby , Bains Manpreet 
Published: April 2024

Abstract

Introduction
Providing access to a vape shop-based smoking cessation intervention may simultaneously increase e-cigarette use and increase the effectiveness of e-cigarettes for smoking cessation. The aim of this study was to identify the most important elements of vape shop-based smoking intervention to stakeholders who would be involved in delivering or accessing such an intervention.

Aims and Methods
We conducted a three-round Delphi study of vape shop staff (n = 40), stop smoking professionals and tobacco control leads (n = 30), and smokers, vapers, and dual users (n = 30) in the United Kingdom in May–August 2021. In each round participants were asked whether they agreed or disagreed with statements related to vape shop-based interventions.

Results
Forty-six of 95 statements reached consensus in round 1, 29 out of 49 in round 2, and 8 out of 20 in round 3. There was support for a vape shop-based intervention across stakeholder groups (96%). There was consensus that the service should comprise both product (98%) and behavioral support (97%), and that quitting vaping should not be a goal of the service (79%). Although there was consensus that there should be some free product provision, there was less consensus as to what this should involve. Views were mostly consistent across stakeholder groups.

Conclusions
There was broad consensus on how to deliver a vape shop-based smoking cessation intervention, providing a strong basis for future intervention development and implementation. Challenges around misuse of the service and misperceptions about vaping would need to be addressed for such an intervention to be feasible and effective.

Implications
Many smokers who make a quit attempt using e-cigarettes purchase their vaping products in vape shops. Delivering vape-shop-based smoking cessation interventions could help to maximize the effectiveness of e-cigarettes for quitting smoking. This study used a Delphi approach to identify the most important elements of a vape shop-based intervention among stakeholders. The findings could be used to help develop future interventions.
Body Impossible
Authors: Osterweis Ariel 
Published: April 2024

Abstract
Body Impossible: Desmond Richardson and the Politics of Virtuosity theorizes the concept of virtuosity in contemporary dance and performance. A virtuoso for the ages, Desmond Richardson is a dancer renowned for delivering commanding performances over decades in contexts ranging from the stages of the Alvin Ailey American Dance Theater and Ballett Frankfurt to featured appearances with Michael Jackson and Prince. He also co-founded Complexions Contemporary Ballet, inaugurating a virtuosic queer black aesthetic with choreographer Dwight Rhoden. Focusing on Richardson’s creative insistence on improvisatory fun and excellence throughout the decades approaching the millennium (shaped by Reaganism, the Culture Wars, the AIDS epidemic, the New Jim Crow, and MTV), this book brings dance into conversation with paradigms of blackness, queerness, masculinity, and class in order to generate a socio-culturally attentive understanding of virtuosity. Virtuosity obscures the border between popular and concert performance, and Richardson’s versatility epitomizes the demands on the contemporary virtuosic dance artist. Osterweis suggests that discourses of virtuosity are linked to connotations of excess, and that an examination of the formal and socio-cultural aspects of virtuosic performance reveals under-recognized heterogeneity in which we detect “vernacular” influences on “high art.” In doing so, Body Impossible accounts for the constitutive relationship between disciplined perceptions of virtuosity’s excess and the disciplining of the racialized body in national and transnational contexts.
The Muse of Virtuosity
Authors: Osterweis Ariel 
Published: April 2024

Abstract
Co-founders of Complexions Contemporary Ballet (1994–present) Desmond Richardson and Dwight Rhoden both danced with Alvin Ailey American Dance Theater (AAADT) from 1987 to 1994. Inquiring into Richardson’s dual role as muse and codirector of Complexions brings greater understanding to the type of virtuosity he inaugurated. This chapter puts forward the concept of choreographic falsetto in analyzing the queer of color aesthetics of Complexions Contemporary Ballet. In thinking of the role of virtuosity in terms of gender transgression, this chapter posits that hyperkinetic corporeal performance appears to be both a space of license, on the one hand, and a space of shame, on the other. It claims that virtuosity operates at—and blurs—the border between popular and high art, defining the location of the virtuoso’s potential transgression. By proposing and developing the term choreographic falsetto, the chapter likens Richardson’s virtuosity to that of nineteenth-century virtuoso musicians and composers such as Franz Liszt, on the one hand, and black “post-soul” singers such as Prince, on the other, accounting for a historically and cross-culturally prevalent (if relatively forgotten) aspect of virtuosity, namely, its position at the meeting point of gender, religion, capitalism, and individualism. Instead of dismissing virtuosity as excess, the chapter mines that excess to uncover black street dance influences on concert dance. In doing so, the content of that excess is named, and black and Africanist performance culture is rendered more legible. While Richardson initially attained stardom at AAADT, his contributions to Complexions worked to establish a queer, post-soul aesthetic that lingers in gender ambivalence. This chapter suggests, ultimately, that there is no normal blackness and no normal masculinity.
Seeing the Light
Authors: Morris Peter J.T. , Reed Peter 
Published: April 2024

Abstract
This chapter shows how Roscoe’s stay in Heidelberg, Germany, between 1853 and 1856 had a profound effect on his subsequent career. Drawn to Heidelberg in the small liberal German state of Baden by the allure of working with Robert Bunsen, Roscoe quickly established a good working relationship with the great chemist. He helped Bunsen to develop the Bunsen burner and translated his treatise on gasometry. Having taken his PhD, Roscoe was instructed by Bunsen to explore the new field of photochemistry. Roscoe worked on the photochemical reaction between chlorine and hydrogen, and quickly established the Bunsen-Roscoe Law. The chlorine-hydrogen actinometer was used to discover which part of the spectrum was most chemically active and to investigate the nature of sunlight. This work laid the basis for Bunsen and Kirchhoff’s development of spectroscopy, which Roscoe publicized. Bunsen and Roscoe maintained their relationship through correspondence until Bunsen’s death in 1899.