bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface acoustic wave sensing chip based on acoustic impedance effect: a method for rapid gas leakage detection and respiratory monitoring
Authors: Wang Wen , Cui Baile , Cheng Lina , Jin Jing , Hu Anyu , Ren Zixuan , Xue Xufeng , Liang Yong 
Published: May 2024

Abstract

The transformation of acoustic impedance (AI) in different media regulates the transmission and reflection characteristics of acoustic waves between media, thus enabling many interesting acoustic applications. Here we introduce for the first time a surface acoustic wave (SAW) chip based on the AI effect, which utilizes its piezoelectric effect and unique interdigital transducer to excite a mechanical wave (SAW) propagating along the surface of the piezoelectric crystal, and it features high sensitivity to surface-loaded media such as gases and humidity changes due to the SAW energy being localized on the surface. On this basis, we theoretically established the relationship between surface load AI and SAW propagation loss, and analyzed the influence of AI on acoustic propagation loss under different gas/humidity media using mass conservation and ideal gas state equations. Experimental measurements using SAW chips reveal that the differences in AI generated by different gases trigger different acoustic propagation loss signals, and can achieve wide-range (1-100 v/v%) gas monitoring, with fast response and recovery speeds reaching sub-second levels (t90<1 s, t10<0.5 s). This capability can also be perfectly utilized for human respiratory monitoring, accurately reflecting respiratory status, frequency, and intensity. Therefore, the SAW sensing method and chip based on the AI effect proposed in this work provide a new solution for in-situ detection of gas leaks and precise monitoring of human respiration.
A dual growth mode unique for organic crystals relies on mesoscopic liquid precursors
Authors: Vekilov Peter , Yerragunta Manasa , Tiwari Akash , Chakrabarti Rajshree , Rimer Jeffrey , Kahr Bart 
Published: May 2024

Abstract

Organic solvents host the synthesis of high-value crystals used as pharmaceuticals and optical devices, among other applications. A knowledge gap persists on how replacing the hydrogen bonds and polar attraction that dominate aqueous environments with the weaker van der Waals forces affect the growth mechanism, including its defining feature, whether crystals grow classically, by association of monomers, or nonclassically, by integration of precursors. Here we demonstrate a rare dual growth mode of etioporphyrin I crystals, enabled by liquid precursors that associate with crystal surfaces to generate stacks of layers, which then grow laterally by incorporating solute molecules. We combine time-resolved in situ atomic force microscopy to monitor the evolution of crystal surfaces with microfluidics to measure crystal growth rates; scattering microscopy to characterize the precursors; density functional theory, absorption spectroscopy and molecular simulations to characterize the molecular interactions in the solution; and quantitative optical birefringence to assess crystal quality. Our findings reveal the precursors as mesoscopic solute-rich clusters, a unique phase favored by weak bonds such as those between organic solutes. The lateral spreading of the precursor-initiated stacks of layers crucially relies on abundant solute supply directly from the solution, bypassing adsorption and diffusion along the crystal surface; the direct incorporation pathway may, again, be unique to organic solvents. Clusters that evolve to amorphous particles do not seamlessly integrate into crystal lattices but incorporate as gross defects. Crystals growing fast and mostly nonclassically at high supersaturations are not excessively strained. Our findings demonstrate that the weak interactions with solutes typical of organic solvents promote nonclassical growth modes by supporting liquid precursors and enabling the spreading of multilayer stacks.
Effects of dinotefuran and humic acid on cadmium migration and transformation in sediments
Authors: Wang Haibo , Bian Mengyang , Yao Shuhua , Li Shifeng 
Published: May 2024

Abstract

The heavy application of dinotefuran (DNT) pesticide in agricultural production and the humic acid (HA) ubiquitous in the aqueous systems have burdened the environment as a new pollutant. The chemical fraction and mobility of cadmium (Cd) in sediments of urban river environments in which DNT and HA coexist are poorly understood. In this study, sequential extraction, ultraviolet-visible spectroscopy (UV-vis), fluorescence excitation-emission matrix (EEM), fourier transform infrared spectrometer (FTIR) techniques, and the Stern-Volmer equationwere integrated to identify the effects of DNT, pH, concentration and molecular weight (Mw) fractions of HA on the content and chemical fraction of Cd in sediments. The DNT dosage strongly affected the Fe–Mn oxide-associated Cd chemical fraction in sediments. HA facilitated migration of Cd from sediments to water. Cd release from sediments was also promoted by a lower pH of 5–6 compared to pH 8–9. Increasing concentrations of higher molecular weight HAs of >100 kDa, 30–100 kDa, and 30–10 kDa reduced total Cd, exchangeable/acid soluble fraction, and reducible fraction content in sediments, while 1–10 kDa and <1 kDa HA did not significantly influence Cd chemical fraction or content. The present study provides new insights into the environmental risks and partitioning of Cd in sediments under co-exposure to DNT and HA.
The 1956 eruption of Bezymianny volcano (Kamchatka). Part I - Petrological constraints on magma storage and eruptive dynamics
Authors: Martel Caroline , ERDMANN Saskia , BOUDON Georges , BALCONE-BOISSARD Hélène , OSTORERO Léa , BELOUSOV Alexander , BELOUSOVA Marina , DAVYDOVA Vesta O. , SHCHERBAKOV Vasily D. 
Published: May 2024

Abstract

Bezymianny volcano is an andesitic island arc stratovolcano that started to erupt in 1955 after ~ 1000 years of dormancy. The March 30, 1956, the climactic phase of the eruption was preceded by a four-month-long emplacement of a shallow cryptodome, which triggered a flank collapse violently decompressing the magma into a laterally-directed blast followed by an explosive phase emplacing extensive pumice concentrated pyroclastic density currents (pumice C-PDC). Aiming at constraining the plumbing system below Bezymianny volcano prior to the 1956 eruption, we performed a multiphase textural and petrological study using dense to vesiculated clasts of the blast and pumice samples from the post-blast C-PDC deposits. We inferred the pressure and temperature conditions of magma storage using sample vesicularity, amphibole destabilization rims, volatile contents in melt inclusions, microlite textures, and phase compositions (phenocrysts, microlites, and glasses). We propose a three-level magma storage characterized by a deep reservoir (≥ 200–350 MPa, ≥ 850°C, 4–8 wt% H2O and CO2 up to 1500 ppm, where amphibole is stable), a shallow reservoir (50–100 MPa, 850–900°C, 1.5-4.0 wt% H2O and CO2 < 250 ppm, where amphibole is unstable and quartz crystallizes) in which the pre-cryptodome magma resided and from which the post-blast pumiceous magma originated, and a subsurface cryptodome (< 25 MPa, ~ 900°C, cristobalite crystallized) from which the blast was initiated. This plumbing system provides the framework for constraining the timescales of the 1956 eruptive dynamics (companion paper).
The value and need for more open and FAIR data sharing to bolster biodiversity conservation in Southeast Asia
Authors: Tanalgo Krizler 
Published: May 2024

Abstract

The tropical Southeast Asian region, with its unique geographical characteristics and features, is home to a multitude of distinct species found in 11 nations. However, the availability of biodiversity data for several taxonomic groups remains unclear. In this study, I examined 17,126,598 occurrence records from Southeast Asia in the GBIF database to compare species data turnover in the region and compare them based on taxonomic groups. The analysis revealed significant disparities in data availability and usage between countries and taxonomic groups within SEA using GBIF. Moreover, there were weak and no correlations among species occurrence records, country size, and GDP. Based on my research, I would argue for a more concerted effort to incorporate and implement FAIR data-sharing approaches in biodiversity research in Southeast Asia. This should become a standard in the scientific community and be integrated into existing biodiversity agendas and frameworks, especially for funded research projects. This will enable a better understanding of biodiversity patterns and will facilitate the development of effective conservation strategies in Southeast Asia. This adaptive management approach is critical for responding to emerging threats and ensuring the long-term sustainability of conservation efforts. In conclusion, these initiatives play a crucial role in enhancing biodiversity conservation in SEA by promoting access to information, fostering collaboration, enabling evidence-based decision-making, engaging local communities, and supporting adaptive management practices.
Plant diversity in cocoa, coffee and cashew agroforest in southern Ghana
Authors: Tetteh Daniel 
Published: May 2024

Abstract

The understanding of the significance of cocoa, coffee, and cashew agroforestry systems in maintaining biodiversity and providing ecosystem services is limited in tropical and humid regions worldwide. The aim of this study was to measure the plant species and diversity in these agroforest systems compared to natural forests. We utilized the line transect method and sampled farm plots that were 20 meters by 20 meters and marked every 50 meters in the cocoa, coffee, cashew agroforest, and natural forests. We determined vegetation parameters such as relative density, relative dominance, relative frequency, and important value index of the most common tree species. The majority of individual shade trees were found in the forest reserve. The mean density and basal area of native forest trees were higher in the forest reserves and lower in the cashew agroforest farmland. Khaya ivorensis had the highest relative frequency, followed by the coffee farmlands, while the least was observed in the cashew agroforest. The findings of this study have implications for sustainable management of tropical agricultural production landscapes and contribute to biodiversity conservation in agricultural landscapes.
PD-L1 promotes tumor metastasis by regulating the infiltration of FGFBP2(+)Tm cells in colorectal cancer
Authors: Wang Xi-Shan , Zhuang Meng , Chen Tianli , Liu Jialiang , Lv Jiangfang , Jiang Zheng , Liu Zheng , Tang Jianqiang 
Published: May 2024

Abstract

Tumor infiltrating lymphocytes largely determined tumorigenesis and progression. We found PD-L1 can inhibit the infiltration of memory T cells in vivo and in vitro by reducing the secretion of CXCL9,CXCL10 in colorectal cancer. Clinically, patients with high PD-L1 expression had few memory T cells infiltration, resulting in a higher incidence of tumor metastasis. Furthermore, single-cell sequencing revealed that PD-L1 mainly inhibited the tissue infiltration of a specific Tm cell subset characterized by the expression of FGFBP2 gene. To clarify the distribution of FGFBP2(+)Tm cells, peripheral blood, lymph nodes, colon polyps, primary tumor, and liver metastases samples were collected. As the tumor progressed, the infiltration of FGFBP2(+) memory T cells gradually increased and accumulated in liver metastases. FGFBP2(+) memory T cells were closely correlated with the distribution of CD31 and positively correlated with the neovascularization density and metastatic nodules. By comparing the transcriptome differences between metastatic and non-metastatic lymph nodes, it was revealed that the expression of FGFBP2 and FGF19 were significantly increased in metastatic lymph nodes. Mechanistically, FGF19, the binding factor of FGFBP2 can induce inflammatory cancer-associated fibroblasts resulting in liver metastasis. Therefore, the elevated FGFBP2(+) memory T cells can promote liver metastasis in colorectal cancer.
One Sentence Summary: PD-L1 can inhibit the infiltration of memory T cells, and increased FGFBP2(+)Tm cells can promote tumor metastasis
Comparative genome analysis of the genus Marivirga and proposal of two novel marine species: Marivirga arenosa sp. nov., and Marivirga salinae sp. nov
Authors: Muhammad Neak , Avila Forbes , Kim Song-Gun 
Published: May 2024

Abstract

Background
The phylum Bacteroidota represents a significant proportion of heterotrophic bacteria found in marine ecosystems. Members of the phylum Bacteroidota are actively involved in the degradation of biopolymers such as polysaccharides and proteins. Bacteroidota genomes exhibit a significant enrichment of various enzymes, including carbohydrate-active enzymes (CAZymes), carboxypeptidases, esterases, isomerases, peptidases, phosphatases, and sulfatases. The genus Marivirga, a member of the family Marivirgaceae within the phylum Bacteroidota, comprises six documented species. During a microbial diversity study, three novel Marivirga strains (BKB1-2T, ABR2-2, and BDSF4-3T) were isolated from the West Sea, Republic of Korea.
Results
To explore the taxonomic status and genomic characteristics of the novel isolates, we employed a polyphasic taxonomic approach, which included phylogenetic, chemotaxonomic and comprehensive genome analysis. The three isolates were Gram-stain-negative, aerobic, rod-shaped, moderately halophilic, and had a gliding motility. The average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) values among the two isolates, BKB1-2T and BDSF4-3T, and the six reference strains were 70.5–76.5% for ANI and 18.1–25.7% for dDDH. Interestingly, the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the strains harbor genes for a comprehensive pathway for dissimilatory nitrate reduction to ammonium (DNRA), as well as other nitrogen pathways for the reduction of nitrite, nitric oxide, and nitrous oxide. Additionally, the antiSMASH analysis indicated that the strains contained three to eight biosynthetic gene clusters (BGCs) associated with the synthesis of secondary metabolites. Furthermore, the strains carried a high number of CAZyme ranging from 53 to 152, which was also demonstrated by an in vitro analysis of degradation of the polysaccharide cellulose, chitin, laminarin, starch, and xylan. Additionally, all the strains carried genes for the metabolism of heavy metals, and exhibited tolerance to heavy metals, with minimum inhibitory concentrations (MICs) in millimoles (mM) in ranges of Co2+ (3–6), Cu2+ (0.2–0.4), Ni2+ (3–5), Zn2+ (2–4), Mn2+ (20–50), and Hg2+ (0.3).
Conclusions
Based on polyphasic taxonomic approach, the three isolated strains represent two novel species names Marivirga arenosa sp. nov. (BKB1-2T = KCTC 82989T = InaCC B1618T), and Marivirga salinae sp. nov. (BDSF4-3T = KCTC 82973T = InaCC B1619T).
Assessment of knowledge and practice on the identification and reporting of substandard and falsified medical products among Healthcare providers in Tanzania
Authors: Manyanga Vicky Peter , Ndele Sayuni , Daniel Innocent , Maswaswa Yusuph , Yondu Emili , Nyondo Goodluck G. , Makoye Paul Malaba , Shedafa Raphael , Masota Nelson E. , Nyakirang’ani Nzagi , Sempombe Joseph , Kaale Eliangiringa 
Published: May 2024

Abstract

The circulation of substandard and falsified medical products in the pharmaceutical markets is a global health problem. The existence of these products undermines the efficiency of the healthcare delivery system and economic development. This research aimed at assessing the level of knowledge and practice among Tanzanian healthcare providers on the identification and reporting of substandard and falsified medical products. Participants included pharmacists, medical doctors, nurses, dentists, and medical laboratory scientists holding bachelor’s degrees and providing health services in Tanzania. Google forms were used for data collection and the Statistical Package for Social Sciences (SPSS) 23 was used for data analysis. About 81.9% and 71.2% of respondents were found to have a good level of knowledge and practice on substandard and falsified medical products identification and reporting respectively. However, 92.5% and 84% of the pharmacists were having higher knowledge and practice than other cadres. The age, experience, facility type, and professional cadres were significantly associated with both the respondent’s knowledge and practice. Furthermore, only 13.2% of the respondents reported having learned about substandard and falsified medical products from universities and 53.8% reported having no idea of reporting tools for these products. The level of knowledge and practice of Tanzanian healthcare providers on identifying and reporting substandard and falsified medical products was good. However, regular training and improvement of the medical school's curriculum are necessary to equip Tanzanian healthcare providers with the necessary knowledge and good practice in identifying and reporting Substandard and falsified medical products.
Research article on development study and utility of Swayam Diabetes m- health application, nutrition informatics platform for self-care management of Type 2 Diabetes in home settings
Authors: Sinha Abhijeet Prasad , Singhal Manmohan , Joshi Ashish , Kumar Rohitashwa 
Published: May 2024

Abstract

Background
Type 2 diabetes mellitus (T2DM) prevalence is alarmingly rising in India, one of the nations most affected by this epidemic. Mobile health (mHealth) interventions offer a promising approach to improving diabetes management by providing tools for self-monitoring, education, and support. This article explores the development and utility of mHealth interventions, focusing on Swayam Diabetes mHealth research in the Indian context. Drawing upon existing literature and empirical evidence, the article discusses the effectiveness, challenges, and future directions of m-Health interventions in T2DM management.
Materials and methods
A mixed research study qualitative n = 18 for testing of deigned interventions and quantitative n = 278 people conducted a DBMS questionnaire survey SUS global testing tool was needed for m-Health interventions on diabetes self-care management applications, with n = 55 participants evaluated using the System Usability Score and DBMS a using globally tested tool
Result
78% of participants preferred using an app to monitor their self-care routine, including food intake, nutrition, physical activity, medication usage, and diabetes-related details. The study found a 5.1% improvement in self-care administration, with gender having little influence. Over 55% of participants used a daily diary and found self-management with m-health interventions beneficial. The study found three key themes: a user-centered tool, an interactive interface, and learning from other users.
Conclusion
The results of this study significantly support the alternative hypothesis of the research study and demonstrate a relationship between m-health and improved at-home diabetic self-care management.
Physiological response as a tolerant mechanism to Yellow Sugarcane Aphids (YSA) (S. flava) herbivory on selected commercial sugarcane varieties (Saccharum officinarum)
Authors: sakadzo nyasha , Mubvuma Michael , Mukanga Cocilia , Mabveni Audrey RS , Musundire Robert 
Published: May 2024

Abstract

Physiological tolerance in response to Yellow Sugarcane Aphid feeding remains an unexplored area in the sugar industry of Zimbabwe and elsewhere. A 7 × 2 factorial in a complete randomized block design (CRBD) replicated four times was used, with seven sugarcane varieties (00-1165, ZN 3L, ZN 8, ZN 9, 96-1107, N14 and ZN 10) under two treatments of aphid infestation (un-infested (control) and infested). Results indicated that there were highly significant differences (p< 0.001) amongst the sugarcane varieties on chlorophyll content and percentage chlorophyll loss in control (sprayed) and infested (unsprayed) plots. Summer results recorded a great increase in percentage chlorophyll loss (21.4%) margin scored on ZN 10. Findings of the regression analysis displayed a highly significant (p< 0.001) strong positive correlation (r= 0.85) between chlorophyll loss and aphid number. Summer results showed highly significant differences (p< 0.001) on gas exchange responses in control and infested plots. Nevertheless, in YSA infested plots, 00-1165 recorded the highest compensatory photosynthetic rate (32.52), transpiration rate (4.32), stomata conductance (218.2) when compared to the least obtained from ZN 10 and N14 at day 28. Obtained results of the regression analysis presented highly significant positive correlation between; chlorophyll loss and photosynthesis (r= 0.44), photosynthesis and aphid number (r= 0.57). Ranking of sugarcane varieties was done according to YSA susceptibility; less susceptible (00-1165), moderate susceptible (ZN 3L, ZN 8 and ZN 9) and highly susceptible (96-1107, N14 and ZN 10). Sugarcane growers should add 00-1165 sugarcane variety amongst the existing sugarcane varieties as it is highly tolerant to YSA damage as proven by physiological compensatory and maintaining behavior.
Sex Differences in the Associations of Creatinine to Cystatin C Ratio with Incident Symptomatic Knee Osteoarthritis-Evidence From the CHARLS
Authors: Sun Boran , Ma Lemeng , Nuer Aerman , Yang Yasi , Xiao Wenbo , Jiao Huanli , Huai Xiaochen , Zhu Yun , Wang Yuan , Chen Yongjie , Lu Wenli 
Published: May 2024

Abstract

Background
Little was known about whether Creatinine to Cystatin C Ratio (CCR) can predict the occurrence of symptomatic knee osteoarthritis (KOA). We examined the association between CCR and incident KOA and sex differences among Chinese middle-aged and older adults.
Methods
We included 4,155 participants aged ≥ 45 years in the 2011 and 2015 wave of the China Health and Retirement Longitudinal Study (CHARLS). The incident of symptomatic KOA was defined as participants who were free of symptomatic KOA at baseline and diagnosed with symptomatic KOA at the 4-year follow-up. Logistic regression models were used to explore the relationship between CCR and incidence KOA in both sexes. Restricted cubic analysis was employed to analyze non-linear relationship.
Results
420 participants (10.1%) developed KOA during 4-year follow-up. The multivariable-adjusted odds ratio (OR) for KOA was 0.85 (95% confidence interval (CI), 0.74 to 0.98) per 1 standard deviation (SD) higher of CCR. The significant effect modification by sex was observed (P-interaction = 0.013). The highest tertile of CCR was significantly correlated with a lower incidence of symptomatic KOA in males (OR = 0.50, 95% CI = 0.29–0.88, P = 0.015), but not in females (OR = 0.88, 95% CI = 0.61–1.29, P = 0.522) compared with the lowest tertile. Significant non-linear relationship was identified for male with 75.0 of CCR being an inflection point.
Conclusions
Our findings provided new insights that CCR could serve as a promising biomarker for early KOA screening among Chinese males.