bluuebunny/crossref_metadata_2025_split huggingface dataset:
Joseph as a Model for Faunus-Hermes: Myth, History, and Fiction in the Fourth Century
Authors: Garstad Benjamin 
Published: October 2009

AbstractFaunus-who-is-also-Hermes is one of the composite god-kings dealt with in the polemical Christian 'Picus-Zeus narrative' of the fourth century. The narrative of his life is based on the Biblical account of Joseph, along with the elaborations on Joseph's life in Hellenistic Jewish fiction. Whereas Joseph is a virtuous hero, however, Faunus-Hermes is a villain who practices sorcery and usurpation and ultimately induces men to worship him as a god. The Hellenistic novels and especially the philosophical considerations of Philo of Alexandria accentuate the ambiguities in Joseph which might allow a bad character to be developed out of his good character. The Clementine Recognitions, moreover, offer an understanding of history and human character according to which good and evil come in contrasting and inimical pairs. Altogether, the use of Joseph as a model for Faunus-Hermes allows the author to subtly introduce a moral message in what seems to be a blunt and unadorned history.
Microwave Emission Brightness Temperature Histograms (METH) Rain Rates for Climate Studies: Remote Sensing Systems SSM/I Version-6 Results
Authors: Chiu Long S. , Chokngamwong Roongroj 
Published: October 2009

Abstract
A satellite microwave emission brightness temperature histograms (METH) technique has been applied to Special Sensor Microwave Imager (SSM/I) data taken on board the Defense Meteorological Satellite Program (DMSP) satellites and preprocessed by Remote Sensing Systems (RSS) Co. to produce 21 yr (July 1987–present) of oceanic rainfall products. These rain products are used as input to the Global Precipitation Climatology Project (GPCP) rain maps. Analysis of the METH product using SSM/I version-4 (V4) data shows jumps in vertically polarized 19-GHz brightness temperatures that are attributed to changes in DMSP satellites. A version-6 (V6) SSM/I that corrects for intersatellite differences was released by RSS in 2006. The jumps in the time series are reduced, with most of the changes occurring in the early part of the DMSP F13 data. The bias between RSS V6 and V4 of brightness temperature at 19 and 22 GHz is less than 0.5 K. METH rain rates were reprocessed using V6 data and were analyzed. The 20-yr global mean difference between the METH V4 and V6 is less than 0.3%, with differences as large as 3% in individual years. Trend analyses show increases in the oceanic rain belts, such as the intertropical convergence zone and the South Pacific convergence zone, and in the Bay of Bengal. These rain-rate trends, from both linear trend analysis and empirical mode decomposition analysis, are comparable to the version-2 GPCP analyses but are smaller than those found in the unified microwave ocean retrieval algorithm.
Microwave Backscatter and Extinction by Soft Ice Spheres and Complex Snow Aggregates
Authors: Petty Grant W. , Huang Wei 
Published: October 2009

Abstract
Coupled-dipole approximation (CDA) calculations of microwave extinction and radar backscatter are presented for nonhomogeneous (soft) ice spheres and for quasi-realistic aggregates of elementary ice crystal forms, including both simple needles and real dendrites. Frequencies considered include selections from the Dual-Frequency Precipitation Radar (DPR; 13.4 and 35.6 GHz) and the Global Precipitation Measurement (GPM) Microwave Imager (GMI; 18.7, 36.5, and 89.0 GHz), both slated for orbit on the GPM mission.
The computational method is first validated against Mie theory using dipole structures representing solid ice spheres as well as stochastically generated “soft” ice spheres of variable ice–air ratio. Neither the traditional Bruggeman nor Maxwell Garnett dielectric mixing formula is found to correctly predict the full range of CDA results for soft spheres. However, an excellent fit is found using the generalized mixing rule of Sihvola with ν = 0.85.
The suitability of the soft-sphere approximation for realistic aggregates is investigated, taking into account the spectral dependence of backscatter and/or extinction per unit mass at key DPR and GMI frequencies. Even when spheres of nonequal mass are considered, there is no single combination of fraction and mass that simultaneously captures all the relevant radiative properties. All four aggregate models do, however, exhibit a predictable power-law dependence of the mass extinction coefficient on the total particle mass. Dual-frequency mass extinction ratios are only very weakly dependent on particle masses; moreover, the ratio is found to be approximately proportional to frequency raised to the power 2.5.
The dual-frequency backscatter ratio is found to be a predictable function of the aggregate mass for particles smaller than 3 mg. Above this size, the ratio is strongly sensitive to aggregate shape, a finding that raises concerns about the utility of dual-frequency backscatter ratio measurements whenever larger particles might be present in a volume of air.
The validity of the Rayleigh–Gans approximation applied to radar backscatter from snow aggregates was also examined. Although the dual-frequency backscatter ratio was reasonably well reproduced, the absolute magnitude was not.
A Nonlinear Perspective on the Dynamics of the MJO: Idealized Large-Eddy Simulations
Authors: Wedi Nils P. , Smolarkiewicz Piotr K. 
Published: October 2009

AbstractThe 30–60-day intraseasonal atmospheric oscillation in the equatorial atmosphere, the Madden–Julian oscillation (MJO), is most visible in its signature of outgoing longwave radiation and associated convective centers. Diabatic processes related to tropical convection and two-way atmosphere–ocean interaction are hence generally believed to be crucial in explaining the origin of the MJO phenomenon. However, reliable deterministic forecasting of the MJO in global circulation models and understanding its mechanism remains unsatisfactory. Here a different approach is taken, where the hypothesis is tested that eastward-propagating MJO-like structures originate fundamentally as a result of nonlinear (dry) Rossby wave dynamics. A laboratory-scale numerical model is constructed, where the generation of solitary structures is excited and maintained via zonally propagating meanders of the meridional boundaries of a zonally periodic β plane. The large-eddy simulations capture details of the formation of solitary structures and of their impact on the convective organization. The horizontal structure and the propagation of anomalous streamfunction patterns, a diagnostic typically used in tracing the equatorial MJO, are similar to archetype solutions of the Korteweg–deVries equation, which extends the linear shallow water theory—commonly used to explain equatorial wave motions—to a weakly nonlinear regime for small Rossby numbers. Furthermore, the characteristics of the three-dimensional laboratory-scale numerical results compare well with observed features of the equatorial MJO and thus the study provides indirect evidence of the basic principles underlying the wave-driven eastward propagation of the MJO.
Regimes of Dry Convection above Wildfires: Sensitivity to Fire Line Details
Authors: Kiefer Michael T. , Parker Matthew D. , Charney Joseph J. 
Published: October 2009

AbstractFire lines are complex phenomena with a broad range of scales of cross-line dimension, undulations, and along-line variation in heating rates. While some earlier studies have examined parcel processes in two-dimensional simulations, the complexity of fire lines in nature motivates a study in which the impact of three-dimensional fire line details on parcel processes is examined systematically. This numerical modeling study aims to understand how fundamental processes identified in 2D simulations operate in 3D simulations where the fire line is neither straight nor uniform in intensity. The first step is to perform simulations in a 3D model, with no fire line undulations or inhomogeneity. In general, convective modes simulated in the 2D model are reproduced in the 3D model. In one particular case with strong vertical wind shear, new convection develops separate from the main line of convection as a result of local changes to parcel speed and heating. However, in general the processes in the 2D and 3D simulations are identical. The second step is to examine 3D experiments wherein fire line shape and along-line inhomogeneity are varied. Parcel heating, as well as convective mode, is shown to exhibit sensitivity to fire line shape and along-line inhomogeneity.
The Signature of the Midlatitude Tropospheric Storm Tracks in the Surface Winds
Authors: Booth James F. , Thompson Lu Anne , Patoux Jérôme , Kelly Kathryn A. , Dickinson Suzanne 
Published: October 2009

Abstract
Storm-track analysis is applied to the meridional winds at 10 m and 850 hPa for the winters of 1999–2006. The analysis is focused on the North Atlantic and North Pacific Ocean basins and the Southern Ocean spanning the region south of the Indian Ocean. The spatial patterns that emerge from the analysis of the 850-hPa winds are the typical free-tropospheric storm tracks. The spatial patterns that emerge from the analysis of the surface winds differ from the free-tropospheric storm tracks. The spatial differences between the surface and free-tropospheric storm tracks can be explained by the influence of the spatial variability in the instability of the atmospheric boundary layer. Strongly unstable boundary layers allow greater downward mixing of free-tropospheric momentum (momentum mixing), and this may be the cause of the stronger surface storm tracks in regions with greater instability in the time mean. Principal component analysis suggests that the basin-scale variability that is reflected in the storm-track signature is the same for the free-tropospheric and surface winds. Separating the data based on the boundary layer stability shows that the surface storm track has a local maximum in the region of maximum instability, even when there is no local maximum in the free-tropospheric storm track above the region. The spatial patterns of the surface storm tracks suggest a positive feedback for storm development as follows: 1) an existing storm generates strong free-tropospheric wind variability, 2) the momentum mixing of the unstable boundary layers acts to increase the ocean–atmosphere energy fluxes, and 3) the fluxes precondition the lower atmosphere for subsequent storm development.
Warm Pool and Cold Tongue El Niño Events as Simulated by the GFDL 2.1 Coupled GCM
Authors: Kug Jong-Seong , Choi Jung , An Soon-Il , Jin Fei-Fei , Wittenberg Andrew T. 
Published: October 2009

Abstract
Recent studies report that two types of El Niño events have been observed. One is the cold tongue (CT) El Niño, which is characterized by relatively large sea surface temperature (SST) anomalies in the eastern Pacific, and the other is the warm pool (WP) El Niño, in which SST anomalies are confined to the central Pacific. Here, both types of El Niño events are analyzed in a long-term coupled GCM simulation. The present model simulates the major observed features of both types of El Niño, incorporating the distinctive patterns of each oceanic and atmospheric variable. It is also demonstrated that each type of El Niño has quite distinct dynamic processes, which control their evolutions. The CT El Niño exhibits strong equatorial heat discharge poleward and thus the dynamical feedbacks control the phase transition from a warm event to a cold event. On the other hand, the discharge process in the WP El Niño is weak because of its spatial distribution of ocean dynamic field. The positive SST anomaly of WP El Niño is thermally damped through the intensified evaporative cooling.
Analysis and Simulation of Human Activity Impact on Streamflow in the Huaihe River Basin with a Large-Scale Hydrologic Model
Authors: Yang Chuanguo , Lin Zhaohui , Yu Zhongbo , Hao Zhenchun , Liu Shaofeng 
Published: October 2009

Abstract
A hydrologic model coupled with a land surface model is applied to simulate the hydrologic processes in the Huaihe River basin, China. Parameters of the land surface model are interpolated from global soil and vegetation datasets. The characteristics of the basin are derived from digital elevation models (DEMs) and a national geological survey atlas using newly developed algorithms. The NCEP–NCAR reanalysis dataset and observed precipitation data are used as meteorological inputs for simulating the hydrologic processes in the basin. The coupled model is first calibrated and validated by using observed streamflow over the period of 1980–87. A long-term continuous simulation is then carried out for 1980–2003, forced with observed rainfall data. Results show that the model behavior is reasonable for flood years, whereas streamflows are sometimes overestimated for dry years since the 1990s when water withdrawal increased substantially because of the growing industrial activities and the development of water projects. Observed streamflow and water withdrawal data showed that human activities have obviously affected the surface rainfall–runoff process, especially in dry years. Two methods are proposed to study the human dimension in the hydrologic cycle. One method is to reconstruct the natural streamflow series using local volumes of withdrawals. The simulated results are more consistent with the reconstructed hydrograph than the initially observed hydrograph. The other method is to integrate a designated module into the coupled model system to represent the effect of human activities. This method can significantly improve the model performance in terms of streamflow simulation.
A Coupled Model Study on the Formation and Dissipation of Sea Fogs
Authors: Heo Ki-Young , Ha Kyung-Ja 
Published: October 2009

Abstract
This study examined the impact of air–sea coupling using a coupled atmosphere–ocean modeling system consisting of the Coupled Ocean–Atmosphere Mesoscale Prediction System as the atmospheric component and the Regional Ocean Modeling System as the oceanic component. Numerical experiments for advection and steam fog events were carried out to clarify the modulation of the formation and dissipation of sea fogs by the air–sea temperature difference (air temperature minus sea surface temperature) and the atmospheric stability. The coupled simulation showed that advection fog is obviously controlled by low-level atmospheric stability and downward latent heat flux with oceanic cooling through air–sea coupling. In particular, air–sea coupling stabilizes the low-level atmosphere at the dissipation stage, and then suppresses vertical mixing, which retards the dissipation of advection fog. In the case of a steam fog event, the upward turbulent heat fluxes are increased significantly from the formation time to the mature time. A decrease in sea surface temperature cools the low-level atmosphere, which increases the condensation rate and low-level atmospheric stability, eventually retarding the dissipation of steam fog.
Naval Research Laboratory Multiscale Targeting Guidance for T-PARC and TCS-08
Authors: Reynolds Carolyn A. , Doyle James D. , Hodur Richard M. , Jin Hao 
Published: October 2009

Abstract
As part of The Observing System Research and Predictability Experiment (THORPEX) Pacific Asian Regional Campaign (T-PARC) and the Office of Naval Research’s (ONR’s) Tropical Cyclone Structure-08 (TCS-08) experiments, a variety of real-time products were produced at the Naval Research Laboratory during the field campaign that took place from August through early October 2008. In support of the targeted observing objective, large-scale targeting guidance was produced twice daily using singular vectors (SVs) from the Navy Operational Global Atmospheric Prediction System (NOGAPS). These SVs were optimized for fixed regions centered over Guam, Taiwan, Japan, and two regions over the North Pacific east of Japan. During high-interest periods, flow-dependent SVs were also produced. In addition, global ensemble forecasts were produced and were useful for examining the potential downstream impacts of extratropical transitions. For mesoscale models, TC forecasts were produced using a new version of the Coupled Ocean–Atmosphere Mesoscale Prediction System (COAMPS) developed specifically for tropical cyclone prediction (COAMPS-TC). In addition to the COAMPS-TC forecasts, mesoscale targeted observing products were produced using the COAMPS forecast and adjoint system twice daily, centered on storms of interest, at a 40-km horizontal resolution. These products were produced with 24-, 36-, and 48-h lead times. The nonhydrostatic adjoint system used during T-PARC/TCS-08 contains an exact adjoint to the explicit microphysics. An adaptive response function region was used to target favorable areas for tropical cyclone formation and development. Results indicate that forecasts of tropical cyclones in the western Pacific are very sensitive to the initial state.
The Role of Environmental Influences on Schizophrenia Admissions in Israel
Authors: Aviv Alex , Bromberg Genadi , Baruch Yehuda , Shapira Yinon , Blass David M. 
Published: October 2009

Objective: The role of environmental factors in hospitalization of patients with schizophrenia is incompletely understood. This study attempts to relate the pattern of hospital admissions to environmental variables such as season and to social factors such as nationally celebrated holidays. Methods: Charts of all adults ( n = 4,331) with a discharge diagnosis of schizophrenia admitted to the Abarbanel Mental Health Centre (Bat Yam, Israel) between 1 January 2001 and 31 December 2005 were reviewed. Hospitalizations were classified by gender, first or repeat admission, month and season of admission, and whether or not the admission coincided with a major Jewish holiday period. Results: There was a significant reduction ( p < 0.05) in first admissions for men during April, the month corresponding to Passover, the most widely celebrated holiday in Israel. This pattern was not seen for women or for repeat admissions. There was no significant effect of the season upon admission rates, using two different methods of defining the season. Conclusions: This study demonstrated significant monthly variability in admission rates and a possible protective effect of a widely celebrated public religious holiday. A consistent effect of season upon rates of admission was not found. Future studies need to identify which specific social factors exert a protective or harmful effect and study how knowledge of these effects can be translated into clinical practice.
Glucarpidase rescue in a patient with high-dose methotrexate-induced nephrotoxicity
Authors: Tuffaha Haitham W , Al Omar Suha 
Published: October 2009

Purpose. To describe the successful use of glucar- pidase (carboxypeptidase G2) in the treatment of high-dose methotrexate-induced nephrotoxicity in a patient with osteosarcoma. Summary. A 12-year-old female patient who had been diagnosed with low-grade right mandibular osteosarcoma was started on a protocol of cisplatin plus doxorubicin alternating with high-dose metho- trexate. Following her first dose of methotrexte, she developed acute renal failure and higher than expected 24h methotrexate level of 478μM/L. High-dose leucovorin rescue was started with vigorous hydra- tion and urine alkalinization together with two sessions of hemodialysis. Because her methotrexate level was persistently high, the investigational drug glucarpidase was administered. Methotrexate leveldropped from 65 to 16.3 μM/L after a single dose of glucarpidase measured by fluorescence polarization immunoassay. Leucovorin and urine alkalinization were continued until day 17 when the patient’s kidney function normalized and methotrexate level reached 0.05 μM/L. The patient tolerated glucarpidase well without any significant adverse events. Conclusion. Glucarpidase is a safe and effective agent in the management of high-dose methotrexate-induced nephrotoxicity and delayed methotrexate elimination. J Oncol Pharm Practice (2011) 17: 136—140.
Capecitabine-induced cerebellar toxicity in a patient with metastatic colorectal cancer
Authors: Gounaris Ioannis , Ahmad Athar 
Published: October 2009

Introduction. Capecitabine is an oral fluoropyrimidine that was designed to allow selective activation in tumour tissues, thus reducing toxicity. The neurologic toxicity of 5-fluorouracil, the original fluoropyrimidine, including an ataxic cerebellar syndrome is well described. However, only a few case reports exist describing a similar syndrome associated with capecitabine administration. Case Report. We report a case of reversible cerebellar toxicity during chemotherapy with a combination of capecitabine and oxaliplatin. Discussion. Rare fluoropyrimide-related toxicities are increasingly being reported in association with capecitabine. Clinical vigilance is required to ensure appropriate investigation and treatment.
Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
Authors: Jasperson Lisa K. , Bucher Christoph , Panoskaltsis-Mortari Angela , Mellor Andrew L. , Munn David H. , Blazar Bruce R. 
Published: October 2009

AbstractDuring graft-versus-host disease (GVHD), donor T cells become activated and migrate to tissue sites. Previously, we demonstrated a crucial role for the immunosuppressive enzyme indoleamine 2,3-dioxygenase (IDO) in GVHD regulation. Here, we show that upon arrival in the colon, activated donor T cells produced interferon-γ that up-regulated IDO, causing T-cell anergy and apoptosis. IDO induces GCN2 kinase, up-regulating a T-cell stress response implicated in IDO immunosuppression. Donor T cells did not require GCN2 kinase to respond to IDO, suggesting toxic IDO metabolites, and not tryptophan depletion, were responsible for suppression. When exogenous metabolites were administered, GVHD lethality was reduced. To determine whether IDO could be induced before transplantation for enhanced GVHD suppression, we first determined whether antigen-presenting cells (APCs) or epithelial cells were primarily responsible for IDO expression and subsequent GVHD suppression. Recipients with wild-type versus IDO−/− APCs had increased survival, regardless of epithelial-cell expression of IDO, suggesting that APCs were suitable targets for inducing IDO. Administration of an agonist to toll-like receptor-7/8, a receptor expressed primarily on APCs, induced IDO and reduced injury in the colon and ameliorated lethality. We conclude that IDO up-regulation may have therapeutic potential for preventing GVHD in the clinic.
Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain
Authors: Lin Yi-Ruu , Chen Hwei-Hsien , Lin Yu-Chin , Ko Chien-Hsin , Chan Ming-Huan 
Published: October 2009

AbstractThe antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the bark ofMagnolia officinalis, were investigated on animal paw licking responses and thermal hyperalgesia induced by glutamate receptor agonists including glutamate, N-methyl-D-aspartate (NMDA), and metabotropic glutamate 5 receptor (mGluR5) activator (RS)-2-chloro-5-hydroxyphenylglycine (CHPG), as well as inflammatory mediators such as substance P and prostaglandin E2(PGE2) in mice. The actions of honokiol and magnolol on glutamate-induced c-Fos expression in the spinal cord dorsal horn were also examined. Our data showed that honokiol and magnolol blocked glutamate-, substance P- and PGE2-induced inflammatory pain with similar potency and efficacy. Consistently, honokiol and magnolol significantly decreased glutamate-induced c-Fos protein expression in superficial (I-II) laminae of the L4-L5 lumbar dorsal horn. However, honokiol was more selective than magnolol for inhibition of NMDA-induced licking behavioral and thermal hyperalgesia. In contrast, magnolol was more potent to block CHPG-mediated thermal hyperalgesia. These results demonstrate that honokiol and magnolol effectively decreased the inflammatory pain. Furthermore, their different potency on inhibition of nociception provoked by NMDA receptor and mGluR5 activation should be considered.