bluuebunny/crossref_metadata_2025_split huggingface dataset:
A non-hydrostatic numerical model for simulating regular wave breaking and surf-swash zone motions
Authors: Shirkavand Ali , Farrahi-Moghaddam Kambiz 
Published: April 2024

AbstractIn the present study, a non-hydrostatic two-dimensional vertical model has been developed to simulate the breaking of regular waves and surf-swash zone motions on a sloping beach. The objective of the present study was to estimate parameters at depth. The governing equations, based on the pressure-correction projection method, were solved in two main phases. In the initial phase, intermediate velocities were acquired through the resolution of advection–diffusion and explicit dynamic pressure gradient terms within the momentum equations, employing a time-splitting technique. To ensure local momentum conservation and solution monotonicity, modifications were made to the governing equations and the solution approach. In the second phase, through the substitution of intermediate velocities and the corrected pressure gradient term from the momentum equations into the continuity equation, with the elimination of velocities, a Poisson pressure-correction equation was derived. In the discretization stage, an innovation was proposed to compute horizontal velocities at the locations where vertical velocities are present, significantly reducing computational costs. The equation was then converted into a system of linear equations, which was solved implicitly. Comparisons between numerical results and experiments concerning plunging and spilling breakers reveal that the developed model satisfactorily simulates the outcomes.
Investigation of the correlation between platelet antibodies and peripheral blood cytopenia in patients with hepatocellular carcinoma
Authors: Han Rui , He Hui-Chan , Zhang Wan-Ning , Pan Ze-Tao , Feng Chen-Yang , Liang Ming-Jian , Wu Mei-Yi , Zhong Wei , Lin Wen-Qian 
Published: April 2024

AbstractThe primary triggers that stimulate the body to generate platelet antibodies via immune mechanisms encompass events such as pregnancy, transplantation, and blood transfusion. Interestingly, our findings revealed that a subset of male patients with hepatocellular carcinoma (HCC), despite having no history of transplantation or blood transfusion, has shown positive results in platelet antibody screenings. This hints at the possibility that certain factors, potentially related to the tumor itself or its treatment, may affect antibody production. To delve the causes we initiated this study. We employed a case–control study approach to analyze potential influential factors leading to the positive results via univariate and multivariate regression analysis. We utilized Kendall’s tau-b correlation to examine the relationship between the strength of platelet antibodies and peripheral blood cytopenia. Antitumor medication emerged as an independent risk factor for positive results in HCC patients, and the strength of platelet antibodies positively correlated with the severity of anemia and thrombocytopenia. Without history of blood transfusion, transplantation, pregnancy, those HCC patients underwent recent tumor medication therapy are experiencing peripheral erythrocytopenia or thrombocytopenia, for them platelet antibody screenings holds potential clinical value for prevention and treatment of complications like drug-immune-related anemia and/or bleeding.
In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression
Authors: Mazzocco Claire , Genevois Coralie , Li Qin , Doudnikoff Evelyne , Dutheil Nathalie , Leste-Lasserre Thierry , Arotcarena Marie-Laure , Bezard Erwan 
Published: April 2024

AbstractAmong the several animal models of α-synucleinopathies, the well-known viral vector-mediated delivery of wild-type or mutated (A53T) α-synuclein requires new tools to increase the lesion in mice and follow up in vivo expression. To this end, we developed a bioluminescent expression reporter of the human A53T-α-synuclein gene using the NanoLuc system into an AAV2/9, embedded or not in a fibroin solution to stabilise its expression in space and time. We first verified the expression of the fused protein in vitro on transfected cells by bioluminescence and Western blotting. Next, two groups of C57Bl6Jr mice were unilaterally injected with the AAV-NanoLuc-human-A53T-α-synuclein above the substantia nigra combined (or not) with fibroin. We first show that the in vivo cerebral bioluminescence signal was more intense in the presence of fibroin. Using immunohistochemistry, we find that the human-A53T-α-synuclein protein is more restricted to the ipsilateral side with an overall greater magnitude of the lesion when fibroin was added. However, we also detected a bioluminescence signal in peripheral organs in both conditions, confirmed by the presence of viral DNA corresponding to the injected AAV in the liver using qPCR.
Gilts prefer an open pen to a stall
Authors: Ede Thomas , Ceribelli Mia , Parsons Thomas D. 
Published: April 2024

AbstractStalls or crates are a very common type of housing used on pig farms that restrict an animal’s movement. How this confinement impacts the animal’s affective states is seldom investigated. We conducted a preference test over 7 days where trios of gilts (n = 10 trios, 27.4 ± 1.5 weeks old) had free access between individual self-locking stalls (~ 1.2 m2) and a shared open area allowing 2.8 m2/animal (71% of total area). Gilts had access to ad libitum feed and water both inside the crates and in the open area. After 7 days, personality traits of the animals were assessed with open field (OF) and novel object (NO) tests. Principal Component Analysis (PCA) yielded two main components, which we defined as Passivity and Engagement. The median time spent outside the crate was 95.2% as 21/29 of the gilts exhibited a significant preference for pen over crate during the 7-day trial (p < 0.05). Passivity had no relationship with time spent in the open area, but engagement during OF/NO was associated with less use of the open area (OR = 0.39, 95CI = [0.25, 0.60]). Interestingly, gilts were likely to spend less time in the open area at nighttime compared to daytime (Odds Ratio = 0.49, 95CI = [0.40, 0.60]), as well as experimental days passed (OR = 0.70, 95CI = [0.66, 0.73]). During the first daytime and nighttime, 1/29 and 2/29 animals preferred the crate respectively, whereas by the last daytime and nighttime 5 and 9 gilts preferred the crate respectively (p < 0.05). While both intrinsic (personality) and extrinsic (time of day, experimental day) factors appear to influence the gilt’s housing preferences, most gilts significantly prefer an open area to a crate when free access is provided between the two. A smaller subpopulation of animals developed a preference for stalls but still utilize both the stall and the pen throughout the day.
Human local field potentials in motor and non-motor brain areas encode upcoming movement direction
Authors: Combrisson Etienne , Di Rienzo Franck , Saive Anne-Lise , Perrone-Bertolotti Marcela , Soto Juan L. P. , Kahane Philippe , Lachaux Jean-Philippe , Guillot Aymeric , Jerbi Karim 
Published: April 2024

AbstractLimb movement direction can be inferred from local field potentials in motor cortex during movement execution. Yet, it remains unclear to what extent intended hand movements can be predicted from brain activity recorded during movement planning. Here, we set out to probe the directional-tuning of oscillatory features during motor planning and execution, using a machine learning framework on multi-site local field potentials (LFPs) in humans. We recorded intracranial EEG data from implanted epilepsy patients as they performed a four-direction delayed center-out motor task. Fronto-parietal LFP low-frequency power predicted hand-movement direction during planning while execution was largely mediated by higher frequency power and low-frequency phase in motor areas. By contrast, Phase-Amplitude Coupling showed uniform modulations across directions. Finally, multivariate classification led to an increase in overall decoding accuracy (>80%). The novel insights revealed here extend our understanding of the role of neural oscillations in encoding motor plans.
Memory of elastic collisions drives high minority spin and oscillatory entropy in underdamped chiral spinners
Authors: Li Shengkai , Phan Trung V. , Wang Gao , Khuri Ramzi , Wilson Jared W. , Austin Robert H. , Liu Liyu 
Published: April 2024

AbstractInertial underdamped collisions preserve the memory of physical parameters that existed before the collision, leading to phenomena usually unseen in overdamped systems. Here we probe the less studied inertial chiral matter with spinners on an air table. We show here the emergence of high levels of spin for a minority of (+) handed spinners in the presence of a majority of (−) handed spinners (vice versa). This deep violation of equipartition occurs due to the inertial (memory preserving) nature of elastic collisions between underdamped translating and rotating objects. Underdamped spinners of the same spin sign annihilate their spins when they elastically collide, transferring their spin angular momentum into orbital angular momentum, while oppositely handed spinners tend to preserve their individual spin levels, leading to the pumping of minority spinners to high spin levels. Entropy production and the flow of entropy in this underdamped system are also counter-intuitive, showing dramatic oscillations in time.
Quantum-inspired framework for computational fluid dynamics
Authors: Peddinti Raghavendra Dheeraj , Pisoni Stefano , Marini Alessandro , Lott Philippe , Argentieri Henrique , Tiunov Egor , Aolita Leandro 
Published: April 2024

AbstractComputational fluid dynamics is both a thriving research field and a key tool for advanced industry applications. However, the simulation of turbulent flows in complex geometries is a compute-power intensive task due to the vast vector dimensions required by discretized meshes. We present a complete and self-consistent full-stack method to solve incompressible fluids with memory and run time scaling logarithmically in the mesh size. Our framework is based on matrix-product states, a compressed representation of quantum states. It is complete in that it solves for flows around immersed objects of arbitrary geometries, with non-trivial boundary conditions, and self-consistent in that it can retrieve the solution directly from the compressed encoding, i.e. without passing through the expensive dense-vector representation. This framework lays the foundation for a generation of more efficient solvers of real-life fluid problems.
The early Cretaceous was cold but punctuated by warm snaps resulting from episodic volcanism
Authors: Nordt Lee , Breecker Daniel , White Joseph 
Published: April 2024

AbstractThe Cretaceous is characterized as a greenhouse climate from elevated atmospheric carbon dioxide concentrations, transgressive seas, and temperate ecosystems at polar paleolatitudes. Here we test the hypothesis that the early Cretaceous was a cold climate state with a new Aptian atmospheric carbon dioxide record from the C3 plant proxy and early Cretaceous sea level curve from stable oxygen isotopes of belemnites and benthic foraminifera. Results show that carbon dioxide concentrations were persistently below 840 ppm during the Aptian, validating recent General Circulation Model simulations of ice sheets on Antarctica at those concentrations. In addition, sea level was estimated to be within the ice sheet window for much of the early Cretaceous prior to the Albian. This background state appears to have been episodically interrupted by Large Igneous Province volcanism followed by long-term carbon burial from weathering. We hypothesize that the early Cretaceous was largely an icehouse punctuated by warm snaps.
An effective attention and residual network for malware detection
Authors: Gu Wei , Xing Hongyan , Hou Tianhao 
Published: April 2024

AbstractDue to its open source and large user base, Android has emerged as the most popular operating system. Android's popularity and openness have made it a prime target for malicious attackers. Permissions have received great attention from researchers because of their effectiveness in restricting applications’ access to sensitive resources. However, existing malware detection methods based on permissions are easily bypassed by inter‐application resource access. To address these issues, we combine inter‐application resource access‐related intent features with permission features. Besides, we designed a customized convolutional neural network using two squeeze‐and‐excitation blocks to learn the inherent relationships between multi‐type features. The two basic SE blocks perform squeezing operations based on average pooling and max pooling, respectively, to compute channel‐wise attention from multiple perspectives. We designed a series of experiments based on real‐world samples to evaluate the efficacy of the proposed framework. Empirical results demonstrate that our framework outperforms state‐of‐the‐art methods, achieving an accuracy of 96.29%, precision of 97.52%, recall of 94.63%, F1‐score of 96.06% and MCC of 92.60%. These promising experimental results consistently demonstrate that AMERDroid is an effective approach for Android malware detection.
YOLO‐AFPN: Marrying YOLO and AFPN for external damage detection of transmission lines
Authors: Zhao Zhenbing , Pan Yitian , Guo Guangxue , Zhai Yongjie , Liu Gao 
Published: April 2024

AbstractTo better detect targets that may cause external damage to transmission lines, the authors present You Only Look Once‐Asymptotic Feature Pyramid Network (YOLO‐AFPN), a lightweight but efficient model. Firstly, the authors adopt a feature comparison strategy based on the knowledge of transmission line scenes, which facilitates increased attention to target features during the training. Secondly, the YOLOv8 detection network is built, and the backbone adds three layers of simple parameter‐free attention module, which extracts features while maintaining lightness, and improves the detection capability in complex scenarios. Then, in the feature fusion stage, an AFPN is constructed, which improves the multi‐scale target detection capability while reducing the number of model parameters by asymptotically fusing features that have small semantic gaps between neighbouring layers. When during the training process, the improved Mosaic data augmentation method is used to enhance the number of distributions of small targets, improve the robustness of the model. Finally, the improved model is validated, and the experimental results show that the improved model can achieve mean average precision of 86.1% at 6.6 MB, which is better than the original network for detection and meets the requirements for deployment on edge devices.
Collaborative strategy for electric vehicle charging scheduling and route planning
Authors: Zhang Jingyi , Jing Wenpeng , Lu Zhaoming , Wu Haotian , Wen Xiangming 
Published: April 2024

AbstractDue to varying energy demands and supply levels in different regions, the distribution of power load exhibits an imbalanced state. It contributes to increased power loss and poses a threat to the security constraints of the electrical grid. Simultaneously, the global energy transition has led to a continuous increase in the proportion of renewable energy integrated into the grid. Electric vehicles (EVs), serving as representative of renewable energy, further magnify this load imbalance with their charging requirements, which poses a significant challenge to the stable operation of the grid. Therefore, to ensure the smooth operation of the grid under the context of renewable energy integration, the authors investigate the coordinated strategies of EV charging scheduling and route planning. The authors first model the coupling of the transportation network with the smart grid as a cyber‐physical system. Subsequently, the authors simulate and analyse the daily charging load curve of the network, capturing the travel characteristics of EVs. Based on this, the authors research the EV charging scheduling in both individual and collective travel scenarios during peak and off‐peak hours. For the off‐peak travel period of EVs, a charging schedule strategy based on travel plans is proposed, which reduces the time cost of EV owners' travel. Furthermore, for the collective travel of a large number of EVs within the system, a multi‐EV charging scheduling strategy based on charging station load balancing is presented. This strategy effectively balances the load levels of various charging stations while reducing the overall system travel time. Ultimately, through experimental results, the authors demonstrate that by deploying appropriate charging scheduling strategies, EVs cease to be a burden on the grid and can be transformed into tools for balancing the loads across different regions.
Effect of Facial Feminization Surgery (FFS) on Eyelid Anatomic Features
Authors: Luong Hanna N. , Liu Alice S. , Sharaf Basel A. , Bite Uldis , Wagner Lilly H. 
Published: April 2024

AbstractFacial feminization surgery (FFS) improves gender dysphoria. The brows and eyes are crucial in perceived gender, yet brow and eyelid surgeries are relatively underutilized. This study aimed to determine rates of brow and eyelid surgeries as part of FFS and characterize pre- and postoperative periocular features. We conducted a retrospective review to identify all patients with the diagnosis of gender dysphoria who underwent FFS at a single academic institution from 2019 to 2022. Thirty-four patients comprising 38 surgical cases were included. Twelve (35%) eyelid surgeries and 27 (79%) brow lifts were performed. Baseline eyelid measurements did not differ between brow lift and nonbrow lift cases. Those undergoing brow lift and eyelid surgery were older in age (p = 0.022), had a higher rate of negative canthal tilt (p = 0.050), and smaller baseline margin-reflex distance 1 (p = 0.014) than patients who had brow lift alone. Brow lift increased tarsal platform show (p ≤ 0.001) and lash-to-brow distance (p ≤ 0.001), and upper blepharoplasty increased tarsal platform show (p = 0.01). Rates of brow lift are high at our institution, and patients are appropriately selected for eyelid surgery in FFS. Brow lift and upper blepharoplasty can feminize anatomical features when using standards described for cisgender cohorts. The impact of periocular features on gender perception in transgender patients warrants further study.
Isolated, Proximal Tibiofibular Injuries in Athletic Patients: A Critical Analysis Review
Authors: Knapik Derrick M. , Gopinatth Varun , Jackson Garrett R. , LaPrade Robert F. , Chahla Jorge , Brophy Robert H. , Matava Matthew J. , Smith Matthew V. 
Published: April 2024

AbstractWhile infrequently reported, isolated injuries to the proximal tibiofibular (TF) joint primarily occur in young, athletic patients participating in sporting activities requiring explosive, high-impact movements, increasing the risk for potential twisting injuries, especially across a hyperflexed knee. The proximal TF joint is stabilized by bony, muscular and ligamentous structures, including both the anterior and posterior proximal TF complexes, with the anterior complex providing more robust stability. Proximal TF injuries frequently involve anterior and lateral displacement of the proximal fibula relative to its native articulation with the tibia. Proper diagnosis is dependent on careful and meticulous history and physical examination, as missed injuries are common, leading to the potential for continued pain, weakness and disability, especially in athletic patients. While spontaneous joint reduction has been reported, injuries may require formal closed reduction, with irreducible and chronic injuries requiring open reduction and stabilization, with recent investigations reporting satisfactory outcomes following anatomic reconstruction of the proximal TF ligament.
Short-term Comparison of Survivorship and Functional Outcomes for Metaphyseal Cones with Short and Long Stems in Revision Total Knee Arthroplasty
Authors: Piuzzi Nicolas S. , Hampp Emily L. , Shi Sarah , Bhowmik-Stoker Manoshi , Huffman Nickelas , Denehy Kevin M. , Markel David C. , Li Daniel D. , Mont Michael A. 
Published: April 2024

AbstractPrinted porous titanium metaphyseal cones have become a mainstay for managing bone loss in revision total knee arthroplasty (rTKA). A short or long stem is routinely used when implanting a cone to augment fixation and offload stresses. This retrospective analysis compared the short-term survivorships and functional outcomes for use of a short or long stem with a metaphyseal cone.A total of 179 cases using metaphyseal cones and stems with median follow-up of 1.95 years (interquartile range, 1.00–2.14) were compared based on stem type. There were 55 cases with long stem(s) and 124 cases with short stem(s). Cases with both long and short stems were excluded. Demographics, Kaplan–Meier survivorships, and preoperative and 1-year postoperative patient-reported outcome measures (PROMs; 2011 Knee Society Score [KSS] objective knee score, function, and satisfaction scores; EuroQol five-dimension scale; and Short Form Survey Physical Component Summary and Mental Component Summary scores) were compared using t-tests with a significance level of α = 0.05. There were no significant differences in body mass index (mean ± standard deviation) or sex (men [%]) between the short and long stem cohorts (32.3 ± 5.3, 36.3% and 31.5 ± 5.5, 38.2%, respectively; p > 0.05). Patients who had short stems were younger (65.9 ± 8.8 vs. 69.0 ± 9.4, p = 0.0323).Revision-free survivorship for the femoral or tibial component was 100% for long stems and 98.2% for short stems at 1 and 2 years, respectively (log-rank p = 0.6330). The two revisions in the short group were for infection, thus the survivorship for aseptic loosening was 100% at 2 years for both cohorts. There were no significant differences in preoperative or postoperative PROMs.This study demonstrated that highly porous printed metaphyseal cones provided rTKA with excellent early survivorship and similar PROMs whether a short or long stem was used. Additional studies will be needed to discern longer term differences.