bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns of health service use for children with mental disorders in an Australian state population cohort
Authors: Watkeys Oliver J , O’Hare Kirstie , Dean Kimberlie , Laurens Kristin R , Tzoumakis Stacy , Harris MAClinEpi Felicity , Carr Vaughan J , Green Melissa J 
Published: June 2024

Objectives: The rate of mental health services provided to children and young people is increasing worldwide, including in Australia. The aim of this study was to describe patterns of hospital and ambulatory mental health service use among a large population cohort of adolescents followed from birth, with consideration of variation by age, sex and diagnosis. Methods: Characteristics of services provided for children with mental disorder diagnoses between birth and age 17.5 years were ascertained for a population cohort of 85,642 children (52.0% male) born between 2002 and 2005, from ‘Admitted Patients’, ‘Emergency Department’ and ‘Mental Health Ambulatory’ records provided by the New South Wales and Australian Capital Territory Health Departments. Results: A total of 11,205 (~13.1%) children received at least one hospital or ambulatory health occasion of service for a mental health condition in the observation period. More than two-fifths of children with mental disorders had diagnoses spanning multiple categories of disorder over time. Ambulatory services were the most heavily used and the most common point of first contact. The rate of mental health service contact increased with age across all services, and for most categories of mental disorder. Girls were more likely to receive services for mental disorders than boys, but boys generally had an earlier age of first service contact. Finally, 3.1% of children presenting to mental health services experienced involuntary psychiatric inpatient admission. Conclusions: The extent of hospital and ambulatory-based mental healthcare service among children emphasises the need for primary prevention and early intervention.
The Grief Cycle: Investigating the Influence of Cycling on Grief Outcomes in Individuals who have Experienced a Bereavement
Authors: Williams Jane , Wingfield Harriet , Chater Angel Marie 
Published: June 2024

Background There is a lack of research that investigates the influence of physical activity on grief outcomes. This research aimed to examine the influence of cycling on grief outcomes in individuals who have experienced a bereavement. Method Semi-structured interviews with 14 participants ( n = 8 males; age M = 47.5 years) who engaged in cycling behaviour and had experienced a bereavement. Reflexive thematic analysis was used to guide analysis. Results Four key themes were generated, providing: an (1) Embodied experience of cycling, within the 2) Cycling community, helping to provide support, alongside the (3) Nature connectedness, which led to 4) Post traumatic growth, following bereavement. Conclusion Evidence suggests that cycling can provide an opportunity for a physical challenge, an immense connection to nature and a community of support from likeminded individuals. These therapeutic qualities of cycling should be considered for future interventions and add novel findings to the area of cycling, bereavement and grief.
The impact of stretch service goals on unethical behaviors of nurses: A three-wave cross-sectional study
Authors: Li Yali , Shi Haiqing , Feng Taiwen 
Published: June 2024

Background Stretch service goals strive to motivate healthcare practitioners to maintain high quality in service provision. However, little is known about how stretch service goals trigger nurses’ unethical behavior. Research aim This study aimed to investigate the influence of stretch service goals on nurses’ unethical behavior, as well as the mediating effects of patient entitlement and nurses’ emotional dissonance. Research design A quantitative cross-sectional study is designed. Participants and research context We sourced data by conducting a time-lagged three-wave survey study from March to September 2020. Random sampling was used, and data were collected from 422 nurse-patient pairs in Chinese hospitals. Bootstrapping method and structural equation modeling were employed to verify the conceptual model. Ethical considerations The study was approved by the designated authority within hospitals and ethical committees. Results Stretch service goals are not directly related to nurses’ unethical behavior. Stretch service goals can trigger nurses’ unethical behavior via patient entitlement. Patient entitlement and nurses’ emotional dissonance play a chain-mediating role between stretch service goals and nurses’ unethical behavior. Conclusions In the context of the healthcare industry, nurses may engage in unethical behavior due to the pressure of achieving stretch service goals. This study contributes to opening the “black box” of stretch service goals and nurses’ unethical behavior by exploring the chain-mediating effect of patient entitlement and nurses’ emotional dissonance.
Facilitators of and Barriers to the Therapeutic Nurse–Patient Relationship: Perceptions From Psychiatric Mental Health Nurses
Authors: Curran Mary-Jo , Gannon Ray , Rivera Reynaldo R. , Li Ying , Fitzpatrick Joyce J. 
Published: June 2024

BACKGROUND: The therapeutic relationship serves as a cornerstone in psychiatric mental health nursing practice, providing a basis for implementing various interventions. AIMS: This study aimed to explore the perspectives of psychiatric mental health nurses regarding factors that facilitate and impede the therapeutic nurse–patient relationship. METHODS: A descriptive study was conducted among psychiatric mental health nurses employed at two community psychiatric hospitals in the northeast area of the United States. A list of facilitators and barriers was developed based on an extensive literature review and subsequently validated by three experts in the field of psychiatric mental health nursing. Participants rated these factors on a 10-point scale. RESULTS: The study included 74 registered nurses from two psychiatric hospitals, yielding a 24% response rate. The highest-ranked facilitator was awareness that the relationship enables collaborative goal setting with patients. The most significant barrier was insufficient time due to administrative tasks. CONCLUSIONS: This study highlights the importance of understanding facilitators and barriers in the therapeutic nurse–patient relationship. Replicating the study nationally on a larger scale among psychiatric mental health nurses is recommended.
Konectom™ cognitive processing speed test enables reliable remote, unsupervised cognitive assessment in people with multiple sclerosis: Exploring the use of substitution time as a novel digital outcome measure
Authors: Scaramozza Matthew , Chiesa Patrizia A , Zajac Lauren , Sun Zhaonan , Tang Minao , Juraver Adrien , Bartholomé Emmanuel , Charré-Morin Julie , Saubusse Aurore , Johnson Sterling C , Brochet Bruno , Carment Loic , Ruiz Marta , Campbell Nolan , Ruet Aurélie 
Published: June 2024

Background: The Konectom™ smartphone-based cognitive processing speed (CPS) test is designed to assess processing speed and account for impact of visuomotor function on performance. Objective: Evaluate reliability and validity of Konectom CPS Test, performed in clinic and remotely. Methods: Data were collected from people with multiple sclerosis (PwMS) aged 18–64 years and healthy control participants (HC) matched for age, sex, and education. Remote test–retest reliability (intraclass correlation coefficients, ICC); correlation with established clinical measures (Spearman correlation coefficients); group analyses between cognitively impaired/unimpaired PwMS; and influence of age, sex, education, and upper limb motor function on CPS Test measures were assessed. Results: Eighty PwMS and 66 HC participated. CPS Test measures from remote tests had good test–retest reliability (ICC of 0.67–0.87) and correlated with symbol digit modalities test (highest |ρ| = 0.80, p < 0.0001). Remote measures were stable (change from baseline < 5%) and correlated with MS disability (highest |ρ| = 0.39, p = 0.0004) measured by Expanded Disability Status Scale. CPS Test measures displayed sensitivity to cognitive impairment (highest d = 1.47). Demographics and motor function had the lowest impact on CPS Test substitution time, a measure accounting for visuomotor function. Conclusion: Konectom CPS Test measures provide valid, reliable remote measurements of cognitive processing speed in PwMS.
Experimental studies of the explosion resistance of steel plate with an energy-absorbing layers
Authors: Chikhradze Nikoloz , Mataradze Edgar , Chikhradze Mikheil , Tavlalashvili Karlo , Akhvlediani Irakli , Malvenishvili Zurab 
Published: June 2024

The aim of this paper is to examine explosion resistance of a composite structure which consists of the steel plate and energy-absorbing layers. With this end, an experimental study of the deformation of 2-3 mm thick steel plates containing different protective layers, namely, an aluminum honeycomb plate, an aluminum sheet, tubular core, polyurethane foam, or an aramid fabrics layer, subjected to explosion generated air shock wave load, has been carried out. At the initial stage of testing, absorbing properties of various composites were examined under relatively low intensity dynamic loads (820 kPa). The dynamic response was assessed by applying bending attenuation and plate center acceleration attenuation factors. This was followed by testing sandwich structures under critical load conditions, when the plate was demolished or subjected to a substantial residual deformation. The study has shown that the composite containing an aluminum honeycomb plate has higher explosion resistance as compared to other tested composites. The proposed design ensures retention of explosion resistance under relatively high dynamic impacts at a reduced distance W = 0.46 m/kg1/3.
Total mesorectal excision after rectal-sparing approach in locally advanced rectal cancer patients after neoadjuvant treatment: a high volume center experience
Authors: Rega Daniela , Granata Vincenza , Romano Carmela , Fusco Roberta , Aversano Alessia , Ravo Vincenzo , Petrillo Antonella , Pecori Biagio , Di Girolamo Elena , Tatangelo Fabiana , Avallone Antonio , Delrio Paolo 
Published: June 2024

Background: In patient with a complete or near-complete clinical response after neoadjuvant treatment for locally advanced rectal cancer, the organ-sparing approach [watch & wait (W&W) or local excision (LE)] is a possible alternative to major rectal resection. Although, in case of local recurrence or regrowth, after these treatments, a total mesorectal excision (TME) can be operated. Method: In this retrospective study, we selected 120 patients with locally advanced rectal cancer (LARC) who had a complete or near-complete clinical response after neoadjuvant treatment, from June 2011 to June 2021. Among them, 41 patients were managed by W&W approach, whereas 79 patients were managed by LE. Twenty-three patients underwent salvage TME for an unfavorable histology after LE (11 patients) or a local recurrence/regrowth (seven patients in LE group – five patients in W&W group), with a median follow-up of 42 months. Results: Following salvage TME, no patients died within 30 days; serious adverse events occurred in four patients; 8 (34.8%) patients had a definitive stoma; 8 (34.8%) patients undergone to major surgery for unfavorable histology after LE – a complete response was confirmed. Conclusion: Notably active surveillance after rectal sparing allows prompt identifying signs of regrowth or relapse leading to a radical TME. Rectal sparing is a possible strategy for LARC patients although an active surveillance is necessary.
Point-of-care Glycated Hemoglobin (POC-A1c) Testing Helps Early Diagnosis of Diabetes
Authors: Agrawal Rajesh 
Published: June 2024

Just like the DIPSI Guidelines for GDM in India, we must have a rapid screening tool like POC-A1c, which gives an estimate of long-term hyperglycemia and helps early detection. Traditional gold standard methods may delay the diagnosis for an indefinite time, as we have seen in our observations that of those who did not opt for POC-A1c, about 34% did not turn up even after three months. We infer that random capillary blood glucose (with a history of meal timings) of more than 140 mg% using POC-A1c helps in instant diagnosis accuracy of about 93%, or exclusion and necessary action can be taken immediately compared to traditional gold standard methods. It also saves time and is cost-effective as no preparation is required, transportation can be avoided, and it also removes the stress or burden of being positive immediately. We know the important role of POC-A1c in treatment intensification or deintensification in the management of known T2DM patients. We also know that POC-A1c is not recommended for the diagnosis of DM by ADA, but evidence suggests we can opt for RPG and POC-A1c to screen and confirm or exclude T2DM. At the same time, we also recommend large-scale cross sectional studies to recommend POC-A1c as a tool for early screening and diagnosis and definitely reconfirmation is always possible and can be recommended.
Intermittent Tibial Artery Compressibility in the Noninvasive Vascular Laboratory: Implications for Diagnosis and Follow-Up
Authors: Scissons Robert , Ettaher Abraham 
Published: June 2024

Objective: There is limited evidence available regarding intermittent tibial artery compressibility in the published literature. This investigation looks to determine the existence of intermittent tibial artery compressibility, in the noninvasive vascular laboratory. Materials and Methods: Consecutive patients underwent noninvasive arterial physiologic testing. An ankle-brachial index (ABI) ≥1.40 was defined as noncompressible and classified into 4 subgroups: (1) noncompressible single occurrence (NC-S), (2) noncompressible multiple occurrence (NC-M), (3) compressible to noncompressible (C-NC), and (4) intermittently compressible (I-C) ABI. Normal patients were compared to these noncompressible subgroups. Selective risk factors were compared in the C-NC and I-C ABI patient groups. Results: Of the 13 881 patients that were evaluated, 89% had compressible tibial arteries and 11% were noncompressible. Intermittent tibial artery compressibility was present in 11.3% of the patients, with noncompressible arteries. There were 718 patients from the NC-M, C-NC, and I-C subgroupings that had 3014 follow-up exams, over mean duration of 38 ± 27.7 months. The C-NC and I-C subgroup patients averaged 3.3 and 3.6 calcification risk factors, respectively. Conclusion: A subset of patients with intermittent tibial artery compressibility was confirmed in the noninvasive vascular laboratory. Additional research is needed to substantiate these findings and investigate whether intermittent compressibility may be marker for increased cardiovascular risk.
The impact of cognitive-motor interference on balance and gait in hearing-impaired older adults: a systematic review
Authors: Wunderlich Anna , Wollesen Bettina , Asamoah Janek , Delbaere Kim , Li Karen 
Published: June 2024

Abstract
Background
Hearing impairments are a rising burden in our aging society. Hearing loss is associated with reduced cognitive performance as well as decrements in balance and gait. Therefore, impaired hearing affects also dual tasking (DT). The aim of this review is to summarize the evidence for DT performance decrements of older adults with hearing impairments during maintaining balance or walking.

Methods
The systematic literature research according to PRISMA guidelines was conducted using MEDLINE, APA Psych-Info, and Web of Science. Inclusion criteria were: Independent living older people ≥ 60 years with hearing impairments, use of a DT paradigm to test hearing impaired older adults within a balance or walking condition.

Results
N = 57 studies were found within the databases. Eight studies were included (N = 456 participants (58% women), including n = 200 older hearing-impaired persons with different levels of hearing loss). Most of the included studies oriented their inclusion criteria for hearing-impairments at thresholds for mild hearing loss with Pure Tone Average (0.5-4 kHz) ≥ 25 and < 40 dB. Three of the studies focused on DT balance performance and five used DT walking comparing participants with and without hearing loss. For DT balance and gait performance, higher decrements for the hearing-impaired group were observed compared to healthy older adults. Performance decrements were accompanied by reduced compensatory strategies in balance performance.

Conclusion
More pronounced decrements in DT performance were observed for participants with hearing impairments compared to those without. This implies that hearing-impaired older adults might need specific interventions to reduce the cognitive-motor interference (CMI) to maintain balance control or walking stability in daily situations that require managing of cognitive and motor tasks simultaneously. However, taking all results into account the underlying mechanisms of CMI for this target group needs to be further examined.

Trial registration
This review was registered at Prospero with the ID CRD42022340232.
Nanoscale insights into hematology: super-resolved imaging on blood cell structure, function, and pathology
Authors: Liu Jinghan , Tan Yuping Yolanda , Zheng Wen , Wang Yao , Ju Lining Arnold , Su Qian Peter 
Published: June 2024

AbstractFluorescence nanoscopy, also known as super-resolution microscopy, has transcended the conventional resolution barriers and enabled visualization of biological samples at nanometric resolutions. A series of super-resolution techniques have been developed and applied to investigate the molecular distribution, organization, and interactions in blood cells, as well as the underlying mechanisms of blood-cell-associated diseases. In this review, we provide an overview of various fluorescence nanoscopy technologies, outlining their current development stage and the challenges they are facing in terms of functionality and practicality. We specifically explore how these innovations have propelled forward the analysis of thrombocytes (platelets), erythrocytes (red blood cells) and leukocytes (white blood cells), shedding light on the nanoscale arrangement of subcellular components and molecular interactions. We spotlight novel biomarkers uncovered by fluorescence nanoscopy for disease diagnosis, such as thrombocytopathies, malignancies, and infectious diseases. Furthermore, we discuss the technological hurdles and chart out prospective avenues for future research directions. This review aims to underscore the significant contributions of fluorescence nanoscopy to the field of blood cell analysis and disease diagnosis, poised to revolutionize our approach to exploring, understanding, and managing disease at the molecular level.
Graphical Abstract
Effect of high-flow nasal cannula at different flow rates on diaphragmatic function in subjects recovering from an acute exacerbation of COPD: a physiological prospective pilot study
Authors: Colaianni-Alfonso Nicolás , Castro Iván , Cáceres Vanesa , Montiel Guillermo , Maggiore Salvatore Maurizio , Vetrugno Luigi 
Published: June 2024

Abstract
Background
Noninvasive ventilation (NIV) is widely employed as the initial treatment for patients with chronic acute exacerbation of obstructive pulmonary disease (AECOPD). Nevertheless, high-flow nasal cannula (HFNC) has been increasingly utilized and investigated to mitigate the issues associated with NIV. Flow rate may play a significant role in diaphragmatic function among subjects recovering from AECOPD. Based on these observations, we conducted a physiological study to assess the impact of HFNC therapy on diaphragmatic function, as measured by US, respiratory rate (RR), gas exchange, and patient comfort at various flow rates.

Methods
A prospective physiological pilot study enrolled subjects with a diagnosis of AECOPD who required NIV for more than 24 h. After stabilization, these subjects underwent a 30-min trial using NIV and HFNC at different sequential flow rates (30–60 L/min). At the end of each trial, diaphragmatic displacement (DD, cm) and diaphragmatic thickness fraction (DTF, %) were measured using ultrasound. Additionally, other physiological variables, such as RR, gas exchange, and patient comfort, were recorded.

Results
A total of 20 patients were included in the study. DD was no different among trials (p = 0.753). DTF (%) was significantly lower with HFNC-30 L/min compared to HFNC-50 and 60 L/min (p < 0.001 for all comparisons). No significant differences were found in arterial pH and PaCO2 at discontinuation of NIV and at the end of HFNC trials (p > 0.050). During HFNC trials, RR remained unchanged without statistically significant differences (p = 0.611). However, we observed that HFNC improved comfort compared to NIV (p < 0.001 for all comparisons). Interestingly, HFNC at 30 and 40 L/min showed greater comfort during trials.

Conclusions
In subjects recovering from AECOPD and receiving HFNC, flows above 40 L/min may not offer additional benefits in terms of comfort and decreased respiratory effort. HFNC could be a suitable alternative to COT during breaks off NIV.
The Association of Female and Male Preconception Dyslipidemia With Live Birth in Couples Seeking Fertility Treatment
Authors: Bollig Kassie J , Barnhart Kurt T , Schisterman Enrique F , Johnstone Erica Boiman , Peterson C Matthew , Hotaling James M , Ryan Ginny , Van Voorhis Bradley J , Carrell Douglas T , Mendola Pauline , Mills James L , Harhay Michael O , Zee Jarcy , Mumford Sunni L 
Published: June 2024

Abstract

Context
Dyslipidemia is common, and resultant endothelial dysfunction may impact reproductive outcomes. No prospective study has examined the effect of preconception lipid parameters in both female and male partners or their interaction on live birth.

Objective
To determine whether live birth is associated with preconception lipids in both partners by planned fertility treatment.

Design
Secondary analysis of the Folic Acid and Zinc Supplementation Trial, conducted between June 2013 and December 2017. Couples were followed for 9 months after randomization and until delivery.

Setting
Multicenter study.

Participants
Couples seeking fertility treatment (n = 2370; females 18-45 years, males ≥18 years).

Exposures
Female, male, and couple abnormal vs normal preconception lipid concentrations [total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein, triglycerides].

Main Outcome Measures
Live birth.

Results
Among 2370 couples, most males (84%) and females (76%) had at least 1 abnormal lipid parameter. Males planning in vitro fertilization (IVF, n = 373) with elevated LDL had lower probability of live birth than those with normal levels [47.4% vs 59.7%, adjusted relative risk (aRR) 0.79, 95% confidence interval (CI) 0.65-0.98]. In couples planning IVF where both partners had elevated TC or LDL, live birth was lower than those with normal levels (TC: 32.4% vs 58.0%, aRR 0.53, 95% CI 0.36-0.79; and LDL: 41.9% vs 63.8%, aRR 0.69, 95% CI 0.55-0.85). Lipid parameters were not associated with live birth for couples planning non-IVF treatments.

Conclusion
Couples planning IVF where both partners had elevated TC or LDL and males planning IVF with elevated LDL had decreased probability of live birth. These findings may support lipid screening in patients seeking fertility treatment for prognostic information for reproductive outcomes.