bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of separated elastic stockings
Authors: Hirai M , Iwata H , Miyazaki K , Koyama A , Nakamura H 
Published: April 2012

Objectives To investigate the acceptability of newly developed separated elastic stockings, which are divided into two portions at the ankle. Methods The difficulty in putting on and taking off stockings was compared between the original or modified separated stockings with various techniques in order to reduce the shift of the stockings and current non-separated stockings in healthy volunteers and patients with lymphoedema by applying both stockings alternately. In the modified model, the shift during daily activities was measured in healthy volunteers and patients with lymphoedema. Results The two items, ‘easier compared with non-separated stockings’ and ‘much easier’, were chosen at rates of 75% and 81% for putting on and taking off stockings for the original separated stockings and 75% and 75% for the modified separated stockings, respectively. Complaints during daily activities with the modified type to the stockings decreased as compared with the original type. The shift of stockings after an average 11-hour application was 1.6 ± 3.0 SD mm (range: 0–10 mm). Conclusions Modified separated elastic stockings are easier to put on and take off compared with current non-separated stockings, and they can be used safely because of their low-level shift during daily activities.
Self-Perception of Malocclusion Among Nigerian Adolescents Using The Aesthetic Component of The IOTN
Authors: Aikins E.A , daCosta O.O , Onyeaso C.O , Isiekwe M.C 
Published: April 2012

Introduction:The practice of orthodontics is very young in South-South Nigeria and there is need for base line data for informed planning. This study was carried out to investigate the self-perception of malocclusion among Nigerian school children aged 12 to 18 years in order to compare their perception with that of an orthodontist and also to determine the influence of gender and age on self-perception.Materials and Methodology:A total of 612 randomly selected schoolchildren comprising 299 (48.9%) males and 313 (51.1%) females with a mean age of 15 + 2.0 years were included in the study, the Aesthetic Component (AC) of the Index of Orthodontic Treatment Need (IOTN) was the instrument used to measure the perception of malocclusion by both the school children and the orthodontist.Results:Majority of the students (82.5%) rated their teeth towards the more attractive end of the scale (Grades 1-4). Although self - perception was not found to be related to gender, older children (16-18 years) had an increased level of perception of need. Males and older children were found to be more in need of treatment by the orthodontist.Conclusions:A significant difference was found between the orthodontist’s rating and the students’ ratings of the attractiveness of their occlusions. Age and gender were not found to influence self- perceived orthodontic treatment need. Therefore, for effective orthodontic care, self- perception and not only professional assessment must be taken into consideration when formulating treatment plans to ensure patient satisfaction.
Percutaneous Tennis Elbow Release Under Local Anaesthesia
Authors: Nazar MA , Lipscombe S , Morapudi S , Tuvo G , Kebrle R , Marlow W , Waseem M 
Published: April 2012

Introduction:When the non-operative treatment of tennis elbow fails to improve the symptoms a surgical procedure can be performed. Many different techniques are available. The percutaneous release of the common extensor origin was first presented by Loose at a meeting in 1962. Despite the simplicity of the operation and its effectiveness in relieving pain with minimal scarring this procedure is still not widely accepted. This study presents the long-term results of percutaneous tennis elbow release in patients when conservative measures including local steroid injections have failed to relieve the symptoms.Patients and Methods:Percutaneous release of the extensor origin was performed in 24 consecutive patients (seven male and seventeen female), providing 30 elbows for this study. The age of the patients ranged from 26 to 71 years with mean age of 55 years. The technique involved a day case procedure in the operating theatre using local anaesthesia without the need for a tourniquet. The lateral elbow was infiltrated with 5mls 1% lignocaine and 5mls 0.5% bupivicaine with 1:200,000 adrenaline. All operations were performed by the senior author. The patients were assessed post operatively by using DASH (disabilities of arm, shoulder and hand) score and Oxford elbow scores. The mean follow up period was 36 months (1-71months).Results:Twenty one patients returned the DASH and Oxford elbow questionnaires. Four patients were lost in the follow up. The post operative outcome was good to excellent in most patients. Eighty seven percent of patients had complete pain relief. The mean post-op DASH score was 8.47 (range 0 to 42.9) and the mean Oxford elbow score was 42.8 (range 16 to 48). There were no complications reported. All the patients returned to their normal jobs, hobbies such as gardening, horse riding and playing musical instruments.Conclusion:In our experience Percutaneous release of the epicondylar muscles for humeral epicondylitis has a high rate of success, is relatively simple to perform, is done as a day case procedure and has been without complications. Percutaneous release is a viable treatment option after failed conservative management of tennis elbow.
The Integrated Proactive Surveillance System for Prostate Cancer
Authors: Wang Haibin , Yatawara Mahendra , Huang Shao-Chi , Dudley Kevin , Szekely Christine , Holden Stuart , Piantadosi Steven 
Published: April 2012

In this paper, we present the design and implementation of the integrated proactive surveillance system for prostate cancer (PASS-PC). The integrated PASS-PC is a multi-institutional web-based system aimed at collecting a variety of data on prostate cancer patients in a standardized and efficient way. The integrated PASS-PC was commissioned by the Prostate Cancer Foundation (PCF) and built through the joint of efforts by a group of experts in medical oncology, genetics, pathology, nutrition, and cancer research informatics. Their main goal is facilitating the efficient and uniform collection of critical demographic, lifestyle, nutritional, dietary and clinical information to be used in developing new strategies in diagnosing, preventing and treating prostate cancer.
The integrated PASS-PC is designed based on common industry standards – a three tiered architecture and a Service- Oriented Architecture (SOA). It utilizes open source software and programming languages such as HTML, PHP, CSS, JQuery, Drupal and MySQL. We also use a commercial database management system – Oracle 11g. The integrated PASS-PC project uses a “confederation model” that encourages participation of any interested center, irrespective of its size or location. The integrated PASS-PC utilizes a standardized approach to data collection and reporting, and uses extensive validation procedures to prevent entering erroneous data. The integrated PASS-PC controlled vocabulary is harmonized with the National Cancer Institute (NCI) Thesaurus. Currently, two cancer centers in the USA are participating in the integrated PASS-PC project.
The final system has three main components: 1. National Prostate Surveillance Network (NPSN) website; 2. NPSN myConnect portal; 3. Proactive Surveillance System for Prostate Cancer (PASS-PC). PASS-PC is a cancer Biomedical Informatics Grid (caBIG) compatible product. The integrated PASS-PC provides a foundation for collaborative prostate cancer research. It has been built to meet the short term goal of gathering prostate cancer related data, but also with the prerequisites in place for future evolution into a cancer research informatics platform. In the future this will be vital for successful prostate cancer studies, care and treatment.
Renal Replacement Therapy in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation
Authors: Askenazi David J. , Selewski David T. , Paden Matthew L. , Cooper David S. , Bridges Brian C. , Zappitelli Michael , Fleming Geoffrey M. 
Published: April 2012

Summary
Extracorporeal membrane oxygenation (ECMO) is a lifesaving procedure used in neonates, children, and adults with severe, reversible, cardiopulmonary failure. On the basis of single-center studies, the incidence of AKI occurs in 70%–85% of ECMO patients. Those with AKI and those who require renal replacement therapy (RRT) are at high risk for mortality, independent of potentially confounding variables. Fluid overload is common in ECMO patients, and is one of the main indications for RRT. RRT to maintain fluid balance and metabolic control is common in some but not all centers. RRT on ECMO can be performed via an in-line hemofilter or by incorporating a standard continuous renal replacement machine into the ECMO circuit. Both of these methods require specific technical considerations to provide safe and effective RRT. This review summarizes available epidemiologic data and how they apply to our understanding of AKI pathophysiology during ECMO, identifies indications for RRT while on ECMO, reviews technical elements for RRT application in the setting of ECMO, and finally identifies specific research-focused questions that need to be addressed to improve outcomes in this at-risk population.
Analyst Initiations of Coverage and Stock Return Synchronicity
Authors: Crawford Steven S. , Roulstone Darren T. , So Eric C. 
Published: April 2012

ABSTRACT
We examine how the information produced by analysts when they initiate coverage contributes to the mix of firm-specific, industry-, and market-wide information available about the firm. We hypothesize that the first analyst to initiate coverage provides low-cost market and industry information allowing him/her to follow more stocks, whereas subsequent analysts provide firm-specific information to distinguish themselves from existing analysts. We use stock return synchronicity to measure the mix of information available about a firm, with higher synchronicity indicating more industry and market information. Coverage initiations of firms with no prior analyst coverage increase synchronicity, suggesting that analysts produce industry- and market-wide information. In contrast, analysts initiating coverage on firms with existing coverage appear to focus on producing firm-specific information as these initiations lead to reduced synchronicity. Together, our findings indicate that the type of information that analysts produce at initiation depends on the information provided by other analysts.
Data Availability: All data are available from public sources identified in the paper.
CORAL: the prediction of biodegradation of organic compounds with optimal SMILES-based descriptors
Authors: Toropov Andrey , Toropova Alla , Lombardo Anna , Roncaglioni Alessandra , Brita Nicoletta , Stella Giovanni , Benfenati Emilio 
Published: April 2012

Abstract
CORAL software (http:/www.insilico.eu/coral) has been used to build up quantitative structure-biodegradation relationships (QSPR). The normalized degradation percentage has been used as the measure of biodegradation (for diverse organic compounds, n=445). Six random splits into sub-training, calibration, and test sets were examined. For each split the QSPR one-variable linear regression model based on the SMILES-based optimal descriptors has been built up. The average values of numbers of compounds and the correlation coefficients (r2) between experimental and calculated biodegradability values of these six models for the test sets are n=88.2±11.7 and r2=0.728±0.05. These six models were further tested against a set of chemicals (n=285) for which only categorical values (biodegradable or not) were available. Thus we also evaluated the use of the model as a classifier. The average values of the sensitivity, specificity, and accuracy were 0.811±0.019, 0.795±0.024, and 0.803±0.008, respectively.
Instance-based regression with missing data applied to a photocatalytic oxidation process
Authors: Leon Florin , Piuleac Ciprian , Curteanu Silvia , Poulios Ioannis 
Published: April 2012

Abstract
In this paper, a modified nearest-neighbor regression method (kNN) is proposed to model a process with incomplete information of the measurements. This technique is based on the variation of the coefficients used to weight the distances of the instances. The case study selected for testing this algorithm was the photocatalytic degradation of Reactive Red 184 (RR184), a dye belonging to the group of azo compounds, which is widely used in manufacturing paint paper, leather and fabrics. The process is conducted with TiO2 as catalyst (an inexpensive semiconductor material, completely inert chemically and biologically), in the presence of H2O2 (with the role of increasing the rate of photo-oxidation), at different pH values. The final concentration of RR184 is predicted accurately with the modified kNN regression method developed in this article. A comparison with other machine learning methods (sequential minimal optimization regression, decision table, reduced error pruning tree, M5 pruned model tree) proves the superiority and efficiency of the proposed algorithm, not only for its results, but for its simplicity and flexibility in manipulating incomplete experimental data.
Supported H4SiW12O40 catalysts for α-pinene isomerization
Authors: Szücs-Balázs József-Zsolt , Coroş Maria , Woiczechowski-Pop Adrian , Blăniƫă Gabriela , Vlassa Mircea 
Published: April 2012

Abstract
The heterogeneous isomerization of α-pinene was studied at 100, 130 and 160°C using 10% supported H4SiW12O40 (SiW) on SiO2, TiO2 and HZSM-5. The effect of the reaction temperature and the concentration of the catalyst over the conversion of α-pinene and the selectivity of camphene, limonene and terpinolene had been monitored. The recovery, reuse and leaching effect of the catalysts were studied. Simple, environmentally friendly and economic methods for the synthesis of camphene and limonene were developed and optimized.
Explicit expression of Cartan’s connection for Levi-nondegenerate 3-manifolds in complex surfaces, and identification of the Heisenberg sphere
Authors: Merker Joël , Sabzevari Masoud 
Published: April 2012

Abstract
We study effectively the Cartan geometry of Levi-nondegenerate C
6-smooth hypersurfaces M
3 in ℂ2. Notably, we present the so-called curvature function of a related Tanaka-type normal connection explicitly in terms of a graphing function for M, which is the initial, single available datum. Vanishing of this curvature function then characterizes explicitly the local biholomorphic equivalence of such M
3 ⊂ ℂ2 to the Heisenberg sphere ℍ3, such M’s being necessarily real analytic.
Patient-Centered Integrated Motor Imagery Delivered in the Home With Telerehabilitation to Improve Walking After Stroke
Authors: Deutsch Judith E. , Maidan Inbal , Dickstein Ruth 
Published: April 2012

Background and Purpose
This case report describes the clinical reasoning process used to examine a person after stroke and intervene with a novel integrated motor imagery treatment designed for the rehabilitation of walking and delivered in the home through telerehabilitation. The integrated motor imagery treatment consisted of patient-centered goal setting and physical practice combined with motor and motivational imagery.

Case Description
The patient was a 38-year-old woman who had had a diffuse left subarachnoid hemorrhagic stroke 10 years earlier. She lived independently in an assisted living complex and carried a straight cane during long walks or in unfamiliar environments. Examination revealed a slow gait speed, reduced walking endurance, and decreased balance confidence. Although she was in the chronic phase, patient-centered integrated motor imagery was predicted to improve her community mobility. Treatment sessions of 45 to 60 minutes were held 3 times per week for 4 weeks. The practiced tasks included transitioning from sitting to standing, obstacle clearance, and navigation in interior and exterior environments; these tasks were first executed and then imagined at ratios of 1:5. Task execution allowed the creation of a scene based on movement observation. Imagery scenarios were customized to address the patient's goals and observed movement problems. Motivational elements of arousal, problem solving, and reward were embedded in the imagery scenarios. Half of the sessions were provided on site, and the remaining sessions were delivered remotely. Seven sessions were delivered by the clinician in the home, and 5 sessions were delivered using telerehabilitation.

Outcomes
Improvements in motor imagery ability, gait parameters, and balance were observed after training. Most gains were retained at the 3-month follow-up. Compared with on-site delivery, the telerehabilitation sessions resulted in less therapist travel time and cost, as well as shorter therapy sessions.

Discussion
The delivery of integrated motor imagery practice for walking recovery was feasible both on site and remotely.
Long-term natural history of neurofibromatosis Type 2–associated intracranial tumors
Authors: Dirks Michael S. , Butman John A. , Kim H. Jeffrey , Wu Tianxia , Morgan Keaton , Tran Anne P. , Lonser Russell R. , Asthagiri Ashok R. 
Published: April 2012

Object
Neurofibromatosis Type 2 (NF2) is a heritable tumor predisposition syndrome that leads to the development of multiple intracranial tumors, including meningiomas and schwannomas. Because the natural history of these tumors has not been determined, their optimal management has not been established. To define the natural history of NF2-associated intracranial tumors and to optimize management strategies, the authors evaluated long-term clinical and radiographic data in patients with NF2.

Methods
Consecutive NF2 patients with a minimum of 4 years of serial clinical and MRI follow-up were analyzed.

Results
Seventeen patients, 9 males and 8 females, were included in this analysis (mean follow-up 9.5 ± 4.8 years, range 4.0–20.7 years). The mean age at initial evaluation was 33.2 ± 15.5 years (range 12.3–57.6 years). Patients harbored 182 intracranial neoplasms, 164 of which were assessable for growth rate analysis (18 vestibular schwannomas [VSs], 11 nonvestibular cranial nerve [CN] schwannomas, and 135 meningiomas) and 152 of which were assessable for growth pattern analysis (15 VSs, 9 nonvestibular CN schwannomas, and 128 meningiomas). New tumors developed in patients over the course of the imaging follow-up: 66 meningiomas, 2 VSs, and 2 nonvestibular CN schwannomas. Overall, 45 tumors (29.6%) exhibited linear growth, 17 tumors (11.2%) exhibited exponential growth, and 90 tumors (59.2%) displayed a saltatory growth pattern characterized by alternating periods of growth and quiescence (mean quiescent period 2.3 ± 2.1 years, range 0.4–11.7 years). Further, the saltatory pattern was the most frequently identified growth pattern for each tumor type: meningiomas 60.9%, VSs 46.7%, and nonvestibular schwannoma 55.6%. A younger age at the onset of NF2-related symptoms (p = 0.01) and female sex (p = 0.05) were associated with an increased growth rate in meningiomas. The identification of saltatory growth in meningiomas increased with the duration of follow-up (p = 0.01).

Conclusions
Neurofibromatosis Type 2–associated intracranial tumors most frequently demonstrated a saltatory growth pattern. Because new tumors can develop in NF2 patients over their lifetime and because radiographic progression and symptom formation are unpredictable, resection may be best reserved for symptom-producing tumors. Moreover, establishing the efficacy of nonsurgical therapeutic interventions must be based on long-term follow-up (several years).
Occult tumors presenting with negative imaging: analysis of the literature
Authors: Chittiboina Prashant , Connor David E. , Caldito Gloria , Quillin Joseph W. , Wilson Jon D. , Nanda Anil 
Published: April 2012

Object
Some patients presenting with neurological symptoms and normal findings on imaging studies may harbor occult brain tumors that are undetectable on initial imaging. The purpose of this study was to analyze the cases of occult brain tumors reported in the literature and to determine their modes of presentation and time to diagnosis on imaging studies.

Methods
A review of the literature was performed using PubMed. The authors found 15 articles reporting on a total of 60 patients with occult tumors (including the authors' illustrative case).

Results
Seizures were the mode of initial presentation in a majority (61.7%) of patients. The initial imaging was CT scanning in 55% and MRI in 45%. The mean time to diagnosis for occult brain tumors was 10.3 months (median 4 months). The time to diagnosis (mean 7.5 months, median 3.2 months) was shorter (p = 0.046) among patients with seizures. Glioblastoma multiforme (GBM) was found more frequently among patients with seizures (67.6% vs 34.8%, p = 0.013). The average time to diagnosis of GBM was shorter than the time to diagnosis of other tumors; the median time to diagnosis was 3.2 months for GBM and 6 months for other tumors (p = 0.04). There was no predilection for side or location of occult tumors. In adult patients, seizures may be predictive of left-sided tumors (p = 0.04).

Conclusions
Based on the results of this study, the authors found that in patients with occult brain tumors, the time to diagnosis is shorter among patients with seizures and also among those with GBM.
Imitation et création littéraire, la poésie de lettrés à l'époque d'Edo
Authors: Parvulesco-Oya Marguerite-Marie 
Published: April 2012

Les kanshi, poèmes composés en chinois par les japonais, présentent une double difficulté d'approche, d'une part un mode de composition qui dissocie la langue de l'écriture et la langue de la lecture, puisque ces poèmes étaient écrits en chinois mais lus en japonais, et d'autre part, un idéal d'imitation des modèles chinois allant à contre courant de la conception moderne de la création littéraire.
Pour les lettrés chinois et japonais, l'imitation de vers célèbres est avant tout une forme de citation, dont le rôle est, à travers la référence à des poèmes antérieurs, de conférer à leur propres poèmes une dimension supplémentaire. Dans ce sens, l'imitation n'entraîne pas la ressemblance avec les vers "imités", elle n'est pas davantage conformisme, ni négation de la liberté du poète, mais elle a favorisé l'élaboration d'une poétique de l'expression indirecte dont l'intérêt ne se limite pas au domaine spécialisé des rapports entre littératures chinoise et japonaise. La lecture des kanshi, en nous obligeant à réfléchir sur le rôle de l'imitation, la valeur de l'originalité, l'intérêt de la nouveauté, la liberté d'écriture du poète et d'interprétation du lecteur, nous incite à remettre en question certaines de nos idées reçues les mieux établies, et à poser ainsi un regard neuf sur la poésie.