bluuebunny/crossref_metadata_2025_split huggingface dataset:
TBM‐S without active support at the limits of its capabilities /
Authors: Bach Dietmar , Köpf Manfred , Lemmerer Johann , Salcher Nicole 
Published: October 2010

AbstractThree tunnels in the Perschling tunnel chain were driven successively by one TBM‐S. In the course of the first two drives, there were many situations when the TBM‐S without active face support was at the limits of its capabilities. The last tunnel to be driven was the Raingruben Tunnel with a length of 2,100 m. Based on the experience from the first two tunnels, advance ground improvement measures like grouting and groundwater lowering were undertaken in areas expected to be difficult. The measures meant that the drive could pass through the problem zones successfully. After about two thirds of the tunnel length under about 40 m of overburden, there were repeated collapses of the face. These reached a sudden peak with a major collapse of the face with an overbreak 34 m high above the crown, which extended almost to the surface. This blocked the cutterhead and the drive was stopped for five months. Various measures were undertaken in many stages to permit the TBM to restart. On account of the ground improvement works carried out from the surface, the remaining stretch was successfully bored and the tunnel structures of the Perschling chain were completed on schedule.Bei der Tunnelkette Perschling wurden hintereinander drei Tunnel von einer TBM‐S aufgefahren. Im Zuge der ersten beiden Vortriebe kam es zu mehreren Situationen im Grenzbereich der Anwendung einer TBM‐S ohne aktive Ortsbruststützung. Als letzter Tunnel wurde der Raingrubentunnel mit einer Vortriebslänge von 2.100 m aufgefahren. Auf Basis der Erkenntnisse und Erfahrungen aus den ersten beiden Tunnelvortrieben wurden im Vorfeld gebirgsverbessernde Maßnahmen wie Injektionen und Grundwasserabsenkungen in vermutlichen Problembereichen durchgeführt. Aufgrund dieser Maßnahmen konnte der Vortrieb die Problemzonen erfolgreich durchörtern. Nach rund zwei Dritteln der Vortriebsstrecke bei rund 40 m Überlagerung kam es jedoch vermehrt zu Ortsbrustverbrüchen. Diese gipfelten schließlich in einem größeren Ortsbrustverbruch mit einem 34 m hohen Überbruch in der Firste, der knapp unter die Oberfläche reichte. Dadurch wurde der Bohrkopf blockiert, und der Vortrieb stand für fünf Monate still. In weiterer Folge wurden verschiedene Maßnahmen durchgeführt, die das Wiederanfahren der TBM in mehreren Schritten ermöglichten. Aufgrund der durchgeführten Bodenverbesserung von über Tage aus konnte der restliche Vortriebsbereich mit der TBM‐S erfolgreich aufgefahren werden und ermöglichte die zeitgerechte Gesamtfertigstellung des Rohbaus der Tunnelkette Perschling.
The management of heat flow in deep mines /
Authors: Wagner Horst 
Published: October 2010

AbstractWith the ever‐increasing depth of mines, the management of heat has become a key issue for their design and operation. There are two main sources of heat: heat transfer from the rock mass into the mine workings and heat associated with mining operations. The principles of heat transfer from the rock mass are discussed and basic relationships presented. Sources of heat linked to mining operations are discussed. It is shown that in deep‐level mines, heat transfer from the rock mass accounts more than 75 % of total mine heat load. In highly mechanized coal mines, heat from the use of mining machinery is also significant. Some models of heat flow prediction for deep gold mines are presented. It is shown that in the case of deep mines, control of heat flow is more important than increasing refrigeration capacity. Examples of heat flow management methods are given.Durch die ständig zunehmende Teufe der Abbaubetriebspunkte wird die Erdwärme zu einem Schlüsselfaktor hinsichtlich Planung und Betrieb von tiefliegenden Bergwerken. Es gibt zwei Hauptwärmequellen, einerseits den Wärmeübergang vom umgebenden Gebirge in die Grubenbaue sowie wärmeproduzierende Arbeitsvorgänge unter Tage. Dieser Beitrag erörtert die Grundsätze des Wärmetransfers aus dem Gebirge und stellt grundlegende Zusammenhänge dar. Darüber hinaus wird auf Wärmequellen im Bergbaubetrieb eingegangen. In tiefliegenden Bergwerken trägt der Wärmeübergang aus dem Gebirge mehr als 75 % zur gesamten Wärmebelastung bei, im Fall von hoch mechanisierten Kohlebergwerken ist die Wärme von Vortriebs‐ und Gewinnungsmaschinen signifikant. Einige Modelle für die Voraussagung von Wärmeströmen in tiefliegenden Goldbergwerken werden dargestellt. Es zeigt sich, dass die Kontrolle von Wärmeströmen wichtiger ist als die Erhöhung der Kühlleistung. Einige Beispiele zeigen Möglichkeiten zum Umgang mit Wärmeströmen auf.
Approaches to technical solutions for tunnelling in swellable ground /
Authors: Kirschke Dieter 
Published: October 2010

Abstract“Swelling” is generally taken to mean the expansion of a rock due to water absorption. The main intention of this paper is to point out the significant difference between the swelling of clay and claystone (Tonstein) on one hand and the swelling of claystone and marl containing anhydrite on the other. In the opinion of the author, these differences are so large that they should be described as different phenomena. Leopold Müller has already proposed the introduction of different German terms: “Quellen” for clay and “Schwellen” for anhydrite. Unfortunately, this terminology has not caught on, probably because the word swelling is used in English for both processes. The resulting merging has hindered research into anhydrite swelling for decades, and the development of calculation methods and technical solutions for tunnelling in anhydrite‐bearing ground is still at an early stage. In contrast, the problem of clay swelling can be regarded as largely solved.Unter “Quellen” wird ganz allgemein die Ausdehnung eines Gesteins infolge von Wasseraufnahme verstanden. Hauptanliegen des vorliegenden Beitrags ist es, auf die beträchtlichen Unterschiede zwischen Quellvorgängen in Ton und Tonstein einerseits und in anhydrithaltigem Ton‐ und Mergelstein andererseits hinzuweisen. Nach der Überzeugung des Autors sind die Unterschiede so groß, dass man eigentlich von zwei verschiedenen Phänomenen sprechen muss. Schon Leopold Müller hat deshalb getrennte Begriffe einzuführen versucht: “Quellen” für Ton und “Schwellen” für Anhydrit. Bedauerlicherweise hat sich diese Terminologie nicht durchsetzen können, vermutlich auch wegen der Verwendung des Worts “swelling” in der englischen Sprache für beide Vorgänge. Die damit verbundene Gleichsetzung hat jahrzehntelang die Erforschung des Anhydritschwellens behindert. Die Entwicklung von Rechenansätzen und von technischen Lösungen für Tunnel in Anhydritgestein befindet sich letztlich immer noch in einer Frühphase. Dagegen kann das Problem des Tonquellens als weitestgehend gelöst angesehen werden.
Heavy/binge drinking and depressive symptoms in older adults: gender differences
Authors: Choi Namkee G. , DiNitto Diana M. 
Published: October 2010

AbstractObjectivesThe purpose of this study was to examine gender similarity/difference in the association between depressive symptoms (11‐item Center for Epidemiologic Scale for Depression (CES‐D) scores), on the one hand, and frequency and amount of alcohol use, on the other, among older adults.MethodsData came from the National Social Life, Health, and Aging Project (NSHAP), Wave 1, which included a nationally representative probability sample (n = 2924) of community‐dwelling individuals aged 57–85. Heavy/binge drinking was defined as the consumption of 4+ drinks for men and 3+ drinks for women per drinking day. The relationship between CES‐D scores and the frequency and amount of alcohol consumption was tested using gender‐separate, 2‐step ordinary least squares (OLS) regression analyses.ResultsA significant proportion of both men (67.7%) and women (52.2%) had consumed alcohol in the preceding 3 months, and 12.3% of male and 8.4% of female drinkers were heavy/binge drinkers. Substantial differences between male and female heavy drinkers were found in sociodemographics, health status, and social support and social engagement. Regression results show that both frequency of drinking and heavy/binge drinking, as opposed to abstinence, were significantly positively associated with men's CES‐D scores, but not with women's.ConclusionHeavy/binge‐drinking older men may use alcohol to cope with depressive mood, and heavy drinking might also contribute to their social isolation and depressive symptoms. Depression screening and treatment for older men should be accompanied by alcohol screening and treatment and vice versa. Copyright © 2010 John Wiley & Sons, Ltd.
High expression of cancer testis antigens MAGE‐A, MAGE‐C1/CT7, MAGE‐C2/CT10, NY‐ESO‐1, and gage in advanced squamous cell carcinoma of the larynx
Authors: Figueiredo David L. A. , Mamede Rui C. M. , Spagnoli Giulio C. , Silva Wilson A. , Zago Marco , Neder Luciano , Jungbluth Achim A. , Saggioro Fabiano P. 
Published: October 2010

AbstractBackground.Despite diagnostic and therapeutic advances in head and neck cancer, the 5‐year survival of patients with laryngeal cancer has not improved in the last 30 years. Several recent studies indicate that specific targets for immunotherapeutic approaches can be useful in the control of cancer. There is considerable interest in the expression of cancer testis antigens in human cancers since they may serve as the basis for an immunologic approach to therapy.Methods.We evaluated by immunohistochemical analysis the expression of cancer testis antigens MAGE‐A4 (57B), MAGE‐C1 (CT7‐33), MAGE‐A1 (MA454), MAGE‐A3 (M3H67), MAGE‐C2 (CT10.5), NY‐ESO‐1 (E978), and GAGE (GAGE) in squamous cell carcinoma (SCC) of the larynx.Results.A total of 63 cases (57 men and 6 women) of laryngeal SCC were available for this study. The findings were correlated with the clinical course and laboratory data. Expression of at least 1 cancer testis antigen was detected in 42 of 63 of the laryngeal SCCs (67%). In 34 of 42 of the positive cases (81%) there was simultaneous expression of ≥2 cancer testis antigens. There was significant correlation between antigen expression and advanced tumor stage (stage III/IV) in cases with reactivity to only 1 antibody (p = .01) as well as in the cases with reactivity to ≥2 primary antibodies (≥2 mAbs, p = .04). There was no association between survival and expression of any of the analyzed antigens.Conclusions.We find a high incidence of cancer testis antigen expression in SCCs of the larynx, which was correlated with advanced clinical stage. Our data indicate that cancer testis antigens could be valuable vaccine targets in laryngeal tumors, especially in those with a worse prognosis. © 2010 Wiley Periodicals, Inc. Head Neck, 2011
Indirect warnings and instructions produce behavioral compliance
Authors: Wogalter Michael S. , Feng Eric 
Published: October 2010

AbstractMost research on warnings assumes a direct flow of information from the source directly to receivers. Reading a manufacturer's product label or manual are examples of directly received warnings. Some communications, however, involve one or more intervening entities (e.g., another person or organization) that serve to convey warning information to the ultimate receiver. With indirect warnings the information does not come directly from the source manufacturer but comes from another entity. The present research examined whether indirectly received warnings benefit compliance in the absence of directly relayed warnings. Participants performed a computer‐memory installation task, in which compliance to three (subtask) behaviors given in the complete instructions/warnings was measured. The effectiveness of indirect warnings was evident. Indirect warning compliance was nearly as high as (but not significantly different from) the direct warning. Implications for the design of hazard communication systems and for warnings in forensic investigations are discussed. © 2010 Wiley Periodicals, Inc.
The effects of virtual industrial training on mental workload during task performance
Authors: Leung Gilbert T. C. , Yucel Gulcin , Duffy Vincent G. 
Published: October 2010

AbstractThis research examines the impact of task complexity, experience level, hazard perception, and simulated tool breakage on an overall mental workload rating. In this study, 100 participants were tested after using a desktop virtual reality training system that simulated a Computer Numerical Control (CNC) milling operation. Differences based on hazard perception and retention interval were also considered. Training conditions were varied for the participants so that the contribution of visual cues, auditory cues, and written instructions could be tested. The participants were asked to determine the best machining outcome during the training period. Results were consistent with previous literature and indicated that the overall mental workload was significantly influenced by task complexity and experience level. Results also suggested that hazard perception as new contributor could be added to the mental workload model for an industrial task of this type. Moreover, the impact of simulated tool breakage on performance was investigated, and it was found that performance was significantly affected by the presence of simulated tool breakage. © 2010 Wiley Periodicals, Inc.
The vitamin D analogue 2MD increases bone turnover but not BMD in postmenopausal women with osteopenia: Results of a 1-year phase 2 double-blind, placebo-controlled, randomized clinical trial
Authors: DeLuca Hector F , Bedale Wendy , Binkley Neil , Gallagher J Chris , Bolognese Michael , Peacock Munro , Aloia John , Clagett-Dame Margaret , Plum Lori 
Published: October 2010

Abstract
Most osteoporosis drugs act by inhibiting bone resorption. A need exists for osteoporosis therapies that stimulate new bone formation. 2-Methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 (2MD) is a vitamin D analogue that potently stimulates bone formation activity in vitro and in the ovariectomized rat model. In this randomized, double-blind, placebo-controlled study of osteopenic women, the effect of daily oral treatment with 2MD on bone mineral density (BMD), serum markers of bone turnover, and safety were assessed over 1 year. Volunteers were randomly assigned to three treatment groups: placebo (n = 50), 220 ng of 2MD (n = 54), and 440 ng of 2MD (n = 53). In general, 2MD was well tolerated. Although 2MD caused a marked increase in markers of bone formation, it did not significantly increase BMD. Since 2MD also shows marked activity on bone resorption (as revealed by dose-dependent increases in serum C-telopeptide cross-links of type I collagen in this study), 2MD likely stimulated both bone formation and bone resorption, thereby increasing bone remodeling. © 2011 American Society for Bone and Mineral Research.
Treatment of insomnia in adults and children: a practice‐friendly review of research
Authors: Taylor Daniel J. , Roane Brandy M. 
Published: October 2010

AbstractChronic insomnia affects nearly 16% of adults and up to 25% of children. Many clinicians are unfamiliar with the research and practice of psychological treatments of insomnia and thus do not use them with their patients. The primary goals of this article were to (a) review the research support for psychological treatments of adult and child insomnia, and (b) describe those treatments with the highest level of research support in enough detail to allow practitioners to begin to utilize them with their own patients. The adult psychological treatments with the best research support are stimulus control, progressive muscle relaxation, and multimodal cognitive–behavioral therapy, followed by multimodal behavioral therapy, sleep restriction, biofeedback, and paradoxical intention. The child psychological treatments with the highest level of research support are preventive parent education, unmodified extinction, and extinction with parental presence, followed by graduated extinction, bedtime fading/positive routines, and scheduled awakenings. © 2010 Wiley Periodicals, Inc. J Clin Psychol: In Session 66:1–11, 2010.
Hepatoma‐derived growth factor‐related protein‐3: A new neurotrophic and neurite outgrowth‐promoting factor for cortical neurons
Authors: Abouzied Mekky M. , El‐Tahir Heba M. , Gieselmann Volkmar , Franken Sebastian 
Published: October 2010

AbstractHepatoma‐derived growth factor‐related proteins (HRPs) make up a family of six members. Hepatoma‐derived growth factor‐related protein‐3 (HRP‐3) is the only family member whose expression is almost restricted to nervous tissue. Here we show that soluble HRP‐3 acts as a novel neurotrophic factor for cultured primary cortical neurons. Antibody‐mediated neutralization of HRP‐3 function results in neuronal degeneration. In contrast, HRP‐3 as the only addition to a culture medium not supporting neuronal survival rescues neurons to an extent comparable to the addition of FCS. Besides this neuroprotective capability, the protein exerts a neurite outgrowth‐promoting effect when it is presented as a coated substrate but not as a soluble factor. This study points to an important role of HRP‐3 during the development of the nervous system. © 2010 Wiley‐Liss, Inc.
Discrepancies between global reanalyses and observations in the interdecadal variations of Southeast Asian cold surge
Authors: Huang Wan‐Ru , Wang Shih‐Yu , Chan Johnny C. L. 
Published: October 2010

AbstractThe Siberian High (SH) is an important part of the East Asian winter monsoon (EAWM) and is closely linked to cold surges. Previous studies revealed a pronounced decline in the strength of the SH during the late 20th century accompanied with a coherent decrease in the frequency of cold surges. However, studies using different data sets yielded different behaviour of the trends. Here we examine the interdecadal variations of the SH and cold surges deduced from six modern global reanalysis data sets. Discrepancies in such variations are found between the reanalysis data sets and observations as well as among different reanalysis data sets. Such discrepancies contribute to inconsistent interdecadal variations of the cold surge frequency in different reanalysis data sets. Potential causes of this situation are discussed. Copyright © 2010 Royal Meteorological Society
Measurement of arterial plasma oxygenation in dynamic oxygen‐enhanced MRI
Authors: Kershaw Lucy E. , Naish Josephine H. , McGrath Deirdre M. , Waterton John C. , Parker Geoffrey J. M. 
Published: October 2010

AbstractInhaled oxygen can be used as a contrast agent for magnetic resonance imaging, due to the T1 shortening effect of the oxygen dissolved in blood and tissue water. In this study, blood T1 was measured dynamically in 14 volunteers (seven smokers, seven never‐smokers) as the inhaled gas was switched from medical air to 100% oxygen and back to medical air. These T1 values were converted to changes in partial pressure of oxygen, which were found to be in agreement with literature values. There were differences in curve shape and curve height between the smoker and never‐smoker groups, suggesting differences in lung function due to smoking‐related damage. These curves could be used as an input function for modeling of oxygen uptake in tissues. The differences between groups highlight the importance of measuring such an input function for each individual rather than relying on an assumed measurement. Magn Reson Med, 2010. © 2010 Wiley‐Liss, Inc.
Numerical modeling and neural networks to identify model parameters from piezocone tests: I. FEM analysis of penetration in two‐phase continuum
Authors: Obrzud Rafał F. , Truty Andrzej , Vulliet Laurent 
Published: October 2010

AbstractThis study presents a numerical approach designed for material parameter identification for the coupled hydro‐mechanical boundary value problem (BVP) of the piezocone test (CPTU) in normally and lightly overconsolidated clayey soils. The study is presented in two related papers and it explores the possibility of using neural networks (NNs) to solve the complex inverse problem of the penetration test, including partially drained conditions. It has been demonstrated that the development of NN‐based inverse models can be based on training data sets that consist of pseudo‐experimental measurements derived from numerical simulations of the piezocone test. The first paper presents the development of the FE model of the studied problem, which can be used to generate a training data population corresponding to typical piezocone measurements that are obtained for clayey soils. The paper contains a detailed description of the numerical model with a sensitivity analysis with respect to different model parameters including the effect of partial drainage. The analysis also includes the model verification by means of a comparative analysis with numerical models of penetration proposed in the literature, as well as experimental evidence. Finally, owing to the loss of accuracy observed when applying a ‘rough’ frictional interface in the Updated Lagrangian formulation, an equivalent semi‐numerical model for the piezocone test is proposed, taking into account a possible occurrence of partial drainage during penetration. Copyright © 2010 John Wiley & Sons, Ltd.
Inter‐domain pricing: challenges and possible approaches
Authors: Tran Hoang‐Hai , Tuffin Bruno 
Published: October 2010

AbstractTelecommunication networks are now an interconnection of competitive operators that need to cooperate to ensure end‐to‐end delivery of traffic. Inter‐domain agreements have to be performed, and pricing is seen as a relevant way to provide an incentive to intermediate domains for forwarding the traffic of others. In this paper, we first review propositions from the literature. Greatest consideration is given to the Vickrey–Clarke–Groves (VCG) auction because it provides appropriate incentives, leads to an efficient use of the network and satisfies other relevant properties. We highlight, on the other hand, that it is neither budget‐balanced nor robust to collusion—something forgotten in the inter‐domain context. This brings us to review the list of properties that we would ideally like the inter‐domain pricing scheme to satisfy, and claim that no mechanism can satisfy all of them together. We then adapt to inter‐domain other resource allocation and pricing schemes, and discuss which properties are or should be relaxed. Copyright © 2010 John Wiley & Sons, Ltd.
Approximation of a batch consolidation problem
Authors: Chang Junho , Chang Soo Y. , Hong Sung‐Pil , Min Yun‐Hong , Park Myoung‐Ju 
Published: October 2010

AbstractIn batch production systems, multiple items can be processed in the same batch if they share sufficiently similar production parameters. We consider the batch consolidation problem of minimizing the number of batches of a finite set of items. This article focuses on the case in which only one or two items can be processed in a single batch. The problem is NP ‐hard and cannot be approximated within 1.0021 of the optimum under the premise, P≠NP. However, the problem admits a
${{3}\over{2}}$
‐approximation. The idea is to decompose the demands of items so that a maximum matching in the graph on the vertices of the decomposed demands provides a well‐consolidated batch set. © 2010 Wiley Periodicals, Inc. NETWORKS, Vol. 58(1), 12–19 2011
Receding Horizon Control of HIV
Authors: David John , Tran Hien , Banks H. T. 
Published: October 2010

AbstractThis paper describes a model of the immunologic response of the human immunodeficiency virus (HIV) in individuals. It then illustrates how a Receding Horizon Control (RHC) methodology can be used to drive the system to a stable equilibrium in which a strong immune response controls the viral load in the absence of drug treatment. We also illustrate how this feedback methodology can overcome unplanned treatment interruptions, inaccurate or incomplete data and imperfect model specification. We consider how ideas from stochastic estimation can be used in conjunction with RHC to create a robust treatment methodology. We then consider the performance of this methodology over random simulations of the previously considered clinical conditions. Copyright © 2010 John Wiley & Sons, Ltd.