bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Suntik Kb 3 Bulan Terhadap Peningkatan Berat Badan Karyawan Rumah Sakit Mekar Sari Bekasi
Authors: Mudalifah Mudalifah , Futriani Elfira Sri 
Published: May 2024

ABSTRACT Changes in weight gain are a side effect of using contraception. The effect of weight gain is because the hormones contained can facilitate the conversion of carbohydrates and sugar into fat and stimulate the appetite control center in the hypothalamus which causes the acceptor to eat more than usual. The aim of this research was to determine the effect of 3-month contraceptive injections on the weight gain of employees at Mekar Sari Hospital, Bekasi. The research approach used in this research is cross-sectional. The population in this study was 62 Mekar Sari employees who used 3-month contraceptive injections. The sample in this study was 62 people. The sampling technique is total sampling. Researchers used the Chi Square test. The results of the study showed that of the 62 respondents, more than half (60%) used 3-month contraceptive injections for >1 year and more than half (67%) experienced weight gain. The chi–square test results show a p value = 0.010< α= 0.05. There is an effect of using 3-month injectable contraceptives on the increase in body weight of 3-month injectable contraceptive acceptors among Mekar Sari Hospital employees. Advice for mothers who want to become family planning acceptors to be wiser in determining the type of contraception to use. Pay attention to the benefits, advantages and side effects of the contraception you will use. Keywords: 3 Month Injectable Birth Control, Weight Loss, Employee ABSTRAK Perubahan peningkatan berat badan adalah efek samping dari pemakaian kontrasepsi. Efek penambahan berat badan disebabkan karena hormon yang terkandung dapat mempermudah perubahan karbohidrat dan gula menjadi lemak serta merangsang pusat pengendali nafsu makan di hipotalamus yang menyebabkan akseptor makan lebih banyak dari biasanya. Tujuan penelitian ini untuk mengetahui Pengaruh Suntik KB 3 Bulan Terhadap Peningkatan Berat Badan Karyawan RS Mekar Sari Bekasi. Pendekatan penelitian yang digunakan dalam penelitian ini yaitu crossectional. Populasi dalam penelitian ini adalah karyawan mekar sari yang menggunakan suntik KB 3 bulan sebanyak 62 orang. Sampel dalam penelitian ini sebanyak 62 orang. Teknik penentuan sampel dengan total sampling. Peneliti menggunakan uji Chi Square . Hasil penelitian menunjukkan bahwa dari 62 responden lebih dari sebagian (60%)penggunaan KB suntik 3 bulan >1 tahun dan lebih dari sebagian (67%) yang mengalami kenaikan berat badan. Hasil uji chi– square menunjukkan nilai p =0,010< α= 0,05. Ada pengaruh penggunaan kontrasepsi suntik 3 bulan dengan peningkatan berat badan akseptor KB suntik 3 bulan pada karyawan RS Mekar Sari. Saran bagi ibu yang ingin menjadi akseptor KB agar lebih bijak dalam menentukan jenis kontrasepsi yang akan digunakan. Perhatikan manfaat, kelebihan dan efek samping kontrasepsi yang akan digunakan. Kata Kunci: KB Suntik 3 Bulan, Berat Badan, Karyawan
Pelatihan Dewan Kemakmuran Masjid dengan Pengembangan Bisnis Online
Authors: Andriyansah Andriyansah , Wihadanto Ake , Geraldina Ira , Febrianti Rini , Paramitha Diky , Nataliani Nadya Putri 
Published: May 2024

Training of the Mosque Prosperity Council (DKM) with a focus on online business development. This activity aims to equip DKM administrators to develop business units for economic independence in running online businesses and their impact on the welfare of the people. the research was conducted online by involving administrators from the Al-Amanah Kujang Mosque DKM. The research was conducted online by involving administrators from Al-Amanah Kujang Mosque, Jl. Tongkeng Dalam No. 48 Merdeka Sumur Bandung, including material on Digital-Based Indomie Warung Business Model, Use of Social Media to Increase Sales and Digital-Based Indomie Ramen Warung Financial Recording. The results showed a significant increase in the knowledge and skills of DKM administrators in running an online business after attending the training. Prior to the evaluation, the training participants were asked to create an Indomie-based online business unit based on products or services managed by the mosque. The online business is expected to provide additional income for the mosque that is used for DKM.DKM training on online business development is proven to be effective in empowering DKM administrators for economic independence and improving the welfare of the people. This approach can be applied more widely by considering the potential and characteristics of each mosque.
Unveiling the chemical kinetics of aminomethanol (NH2CH2OH): insights into O.H and O2 photo-oxidation reactions and formamide dominance
Authors: Nulakani Naga Venkateswara Rao , Ali Mohamad Akbar 
Published: May 2024

Aminomethanol is released into the atmosphere through various sources, including biomass burning. In this study, we have expounded the chemical kinetics of aminomethanol in the reaction pathways initiated by the hydroxyl radical (O˙H) with the aid of ab initio//density functional theory (DFT) i.e., coupled-cluster theory (CCSD(T))//hybrid-DFT (M06-2X/6-311++G (3df, 3pd). We have explored various possible directions of the O˙H radical on aminomethanol, as well as the formation of distinct pre-reactive complexes. Our computational findings reveal that the H transfer necessitates activation energies ranging from 4.1 to 6.5 kcal/mol from the –CH2 group, 3.5–6.5 kcal/mol from the –NH2 group and 7–9.3 kcal/mol from the –OH group of three rotational conformers. The H transfer from –CH2, –NH2 and –OH exhibits an estimated total rate constant (kOH) of approximately 1.97 × 10−11 cm3 molecule−1 s−1 at 300 K. The branching fraction analysis indicates a pronounced dominance of C-centered NH2C˙HOH radicals with a favorability of 77%, surpassing the N-centered N˙ HCH2OH (20%) and O-centered NH2CH2O˙ (3%) radicals. Moreover, our investigation delves into the oxidation of the prominently favored carbon-centered NH2C˙HOH radical through its interaction with atmospheric oxygen molecules. Intriguingly, our findings reveal that formamide (NH2CHO) emerges as the predominant product in the NH2C˙HOH + 3O2 reaction, eclipsing alternative outcomes such as amino formic acid (NH2COOH) and formimidic acid (HN = C(H)-OH). At atmospheric conditions pertinent to the troposphere, the branching fraction value for the formation of formamide is about 99%, coupled with a rate constant of 5.5 × 10−12 cm3 molecule−1 s−1. Finally, we have scrutinized the detrimental impact of formamide on the atmosphere. Interaction of formamide with atmospheric hydroxyl radicals could give rise to the production of potentially perilous compounds such as HNCO. Further, unreacted N˙HCH2OH radicals may initiate the formation of carcinogenic nitrosamines when reacting with trace N-oxides (namely, NO and NO2). This, in turn, escalates the environmental risk factors.
Three-year outcomes of surgical valve replacement with Dafodil™ pericardial bioprosthesis: Dafodil™-1 trial
Authors: Hiremath Channabasavaraj Shivalingaiah , Jain Anil R. , Garg Anurag , Maslekar Atul A. , Gupta Nirmal K. , Sarkar Binay Krishna , Bhat Seetharama , Porwal Manish , Meharwal Zile Singh , Mishra Yugal Kishore , Vaijyanath Prashanth , Grover Vijay , Chaudhary Shiv Kumar , Rajput Subash S. , Sethuratnam Rajan , Shastri Naman 
Published: May 2024

BackgroundThe Dafodil™-1 trial was designed to evaluate the clinical safety and performance of Dafodil™ pericardial bioprosthesis for replacing diseased native or prosthetic aortic or mitral valves in patients with advanced valvular heart disease (VHD).MethodsThe Dafodil™-1 trial was a prospective, multicenter, first-in-human clinical trial. Patients were enrolled if they had advanced VHD requiring aortic valve replacement (AVR) or mitral valve replacement (MVR) with or without concomitant valve surgery and having surgical risk scores &lt;4%. Major adverse cardiac events (MACE), including all-cause death, myocardial infarction (MI), and stroke; and hemodynamics were analyzed.ResultsA total of 136 patients (aortic: 67 and mitral: 69) were enrolled in the trial (with mean age—AVR group: 60.2 ± 8.3 years and MVR group: 49.7 ± 14.4 years). A total of 134 patients (aortic: 66 and mitral: 68) completed the 3-year follow-up (total 300 per 100 patient-years of follow-up). The AVR group demonstrated a significant reduction in the mean pressure gradients from 51.2 ± 24.1 mmHg at baseline to 11.1 ± 6.0 mmHg at the 3-year follow-up (p &lt; 0.0001). The mean effective orifice area (EOA) improved from baseline (0.9 ± 0.6 cm2) to 3-year follow-up (1.8 ± 0.4 cm2) (p &lt; 0.0001). In the MVR group, the mean indexed EOA (iEOA) increased significantly from baseline (0.7 ± 0.4 cm2/m2) to 3-year follow-up (1.1 ± 0.4 cm2/m2) (p &lt; 0.001). There was significant improvement in New York Heart Association functional class and mean SF-12 scores in both groups. At 3-year follow-up, the MACE incidence was 2.3% per 100 patient-years (1.3% strokes per 100 patient-years and 1.3% deaths per 100 patient-years) for AVR group and 4.7% per 100 patient-years (0.6% strokes per 100 patient-years and 4.0% deaths per 100 patient-years) for MVR group. No cases of MI, structural valve deterioration and prosthetic valve endocarditis were reported. The AVR and MVR groups achieved 89.6% and 79.7% MACE-free survival, respectively at 3-year follow-up.ConclusionsThe Dafodil™-1 trial demonstrated satisfactory outcomes of clinical safety, hemodynamic performance, and quality-of-life metrics. Additionally, no incidence of structural valve deterioration and very low rates of valve thrombosis during the 3-year follow-up period of Dafodil™-1 first-in-human trial indicated acceptable valve durability up to three years and similar outcomes are warranted for longer follow-ups as a primary goal.Clinical Trial Registration Numberhttps://www.ctri.nic.in/Clinicaltrials/showallp.php?mid1=18377&amp;EncHid=&amp;userName=CTRI/2017/07/009008, CTRI/2017/07/009008.
The role of counseling for non-traditional students in formal higher education: a scoping review
Authors: Stamou Panagiota , Tsoli Konstantina , Babalis Thomas 
Published: May 2024

IntroductionSince the mid-20th century, the number of adult students enrolled in formal higher education (HE) programs has significantly increased. The profile of non-traditional students differs significantly from that of traditional students in terms of their characteristics, learning methods, obstacles and challenges, motivations for learning, and conditions for effective learning. Unlike traditional students, adult students often balance family, work, and educational responsibilities, necessitating a more nuanced approach to support and guidance. However, most HE institutions primarily serve the needs of traditional student populations, which results in limited support available to adult students. This scoping review aimed to explore and map the existing literature on the role of adult (or non-traditional) students counseling in the context of formal HE.MethodsWe focused on literature related to academic advising for non-traditional students in formal HE, restricting our search to both empirical and non-empirical articles published in peer-reviewed journals between 2010 and 2022. Employing Arksey and O’Malley’s scoping review method and the PRISMA-ScR Checklist, we searched four databases (EBSCOhost, Crossref, Semantic Scholar, and ERIC), supplemented by a manual search.ResultsOf the 1,330 articles identified and screened, 25 studies met the eligibility criteria. Our review included 17 empirical and eight non-empirical studies, with the majority conducted in the USA (21 of 25). Thematic analysis revealed five key research areas (or themes): academic advising practices, perceptions of advising, technology, and advising, advising models, and academic success. The most common research theme, advising practices for adult (undergraduate and doctoral) students, constituted 52% of the studies (n= 13).DiscussionDrawing from our analysis, we discuss current trends and future development in advising non-traditional students within formal HE settings. The added value of academic advising for adult students is explored, and any potential gaps in research literature knowledge are identified.
Promoting family wellbeing through parenting support in ECEC services: parents' views on a model implemented in Ireland
Authors: Leitão Catarina , Shumba Jefrey 
Published: May 2024

IntroductionProviding support to parents during the children's early years can positively impact children's development and families' wellbeing. An innovative parenting support model within ECEC services, called Powerful Parenting, has been implemented in Ireland. This model involves placing one dedicated Facilitator in each ECEC service to support parents based on their families' needs. The current study aimed to explore parents' views about this model.MethodsTwenty-seven parents were interviewed. Content analysis was used to identify the activities in which parents participated. Thematic analysis was used to explore their views on the model or Facilitators' work.ResultsThe activities organised by the Facilitators in which parents participated included one-to-one meetings, group work, and coordination with other services for children and families. Valued aspects included Facilitators showing high interest in their work, being approachable and responsive to parents' needs, and constituting a central point of contact, bridging the home and the ECEC service. Perceived outcomes for parents included a better understanding of their children's needs, facilitated access to services for families, and socio-emotional benefits.DiscussionA parenting support model involving a new professional role, that of the Facilitator, in ECEC services can potentiate accessible and tailored support according to families' needs.
Parents’ spatial talk to boys and girls in museum settings: variations by science topic and exhibit scale
Authors: Umansky Vera M. , Callanan Maureen A. 
Published: May 2024

IntroductionChildren are exposed to STEM ideas, including spatial and other mathematical concepts, in a variety of everyday contexts through interactions with their parents. There may be variations in the spatial language that boys and girls hear from their parents within different informal contexts. The present study investigated variations in the frequency and type of parental spatial talk that occurred in museum settings that varied by topic (physical science vs. life science) and exhibit scale (small-scale activity vs. large-scale activity).MethodThe sample consisted of 194 families with children between the ages of 3–6 years who visited museums in Northern California. Of the total sample, 50 families visited a large-scale physical science exhibit, 44 families visited a large-scale life science exhibit, 50 families visited a small-scale physical science exhibit, and 50 families visited a small-scale life science exhibit. Parent–child conversations that occurred during the duration of the museum visit were coded for parents’ spatial language.Results and discussionAnalyses revealed that parents in the large-scale life science exhibit used more spatial language than parents in the other exhibits. Additionally, parents used more “where” spatial language (spatial language that describes location and directionality) than “what” spatial language (spatial language that describes the look of something) across the exhibit contexts, but especially in the large-scale exhibits. Finally, boys heard more “where” spatial language than did girls across exhibit contexts, whereas there was no difference by gender for “what” spatial language exposure. Variations in the kinds of spatial language that parents use in different environments should be taken into account in developmental models of children’s spatial understanding. Future research is needed to more systematically explore how parents’ spatial language varies across children’s gender, exhibit topic, and exhibit scale.
Research and optimisation of focused solar heating system with phase change thermal storage
Authors: Zhang Yishu , Zhang Wenqing 
Published: May 2024

Currently, solar heating systems face several challenges in winter cold conditions, including low heat collection temperature, high heat collection loss, low thermal storage density, and unstable storage temperature, making it difficult to meet heating quality requirements. Taking the heating of a driving school building in the suburbs of Baiyin, Gansu as a case study, and using typical meteorological data for the local heating season, we simulated the indoor thermal load of the building using DEST software. We then designed a focused solar heating system with phase change thermal storage, coupling focused solar thermal technology with latent heat storage technology. The thermal storage performance of Ba(OH)2·8H2O composite phase change material in an oil-sealed environment was verified. Mathematical models of the major components of the focused solar heating system with phase change storage were developed, along with a TRNSYS system model. An objective function was established using the annualized cost method, with the area of the collector and the mass of PCM as variables. Optimization was performed using Genopt software, invoking the Hooke-Jeeves algorithm to optimize the heat collection area S and mass m of phase change material in the focused solar heating system. The optimized results showed a collector area of 4.11 m2, and a PCM mass of 130 kg, resulting in a 10.04% improvement in the solar assurance rate. Over the system’s entire lifecycle, the cost decreased by 1025 RMB, and the carbon emission reduction increased from 10,838 to 16,101 kg.
Work-life integration among nurse educators: a meta-synthesis
Authors: Erasmus Sonja , Downing Charlene , Ntshingila Nompumelelo 
Published: May 2024

BackgroundWork-life integration has been extensively researched in various contexts. Women dominate the nursing profession, but work-life integration is essential for men and women since both are expected to focus equally on their families and careers. The nursing faculty perceives nurse educators’ work environment as undervalued, lacking support, and limited time to grow and carry the heavy workload.MethodA qualitative meta-synthesis of studies between 2013 and 2023 was conducted using ScienceDirect, EBSCO Host, Sage and Sabinet databases. Seven articles related to the research phenomenon were retrieved.ConclusionThe resulting themes revolved around two central aspects: nurse educators’ work and life integration. Nurse educators face various challenges with work-life integration and often view their failure as a personal rather than a societal issue. However, as much as achieving work-life integration is personal, there is a call for employers in academic environments to improve workplace policies, like better-paid maternity leave, affordable quality childcare, and social support. Furthermore, nurse educators’ line managers should display warmth and encouragement about personal challenges affecting nurse educators.
Identification of novel biomarkers related to neutrophilic inflammation in COPD
Authors: Huang Yuchen , Niu Yang , Wang Xuezhao , Li Xiaochen , He Yuanzhou , Liu Xiansheng 
Published: May 2024

BackgroundChronic obstructive pulmonary disease (COPD) is one of the most prevalent chronic respiratory diseases and the fourth cause of mortality globally. Neutrophilic inflammation has a vital role in the occurrence and progression of COPD. This study aimed to identify the novel hub genes involved in neutrophilic inflammation in COPD through bioinformatic prediction and experimental validation.MethodsBoth the single-cell RNA sequencing (scRNA-seq) dataset (GSE173896) and the RNA sequencing (RNA-seq) dataset (GSE57148) were downloaded from the Gene Expression Omnibus (GEO) database. The Seurat package was used for quality control, dimensions reduction, and cell identification of scRNA-seq. The irGSEA package was used for scoring individual cells. The Monocle2 package was used for the trajectory analysis of neutrophils. The CIBERSORT algorithm was used for analysis of immune cell infiltration in the lungs of COPD patients and controls in RNA-seq dataset, and weighted gene co-expression network analysis (WGCNA) correlated gene modules with neutrophil infiltration. The Mendelian randomization (MR) analysis explored the causal relationship between feature DEGs and COPD. The protein–protein interaction (PPI) network of novel hub genes was constructed, and real-time quantitative polymerase chain reaction (qRT-PCR) was used to validate novel hub genes in clinical specimens.ResultsIn scRNA-seq, the gene sets upregulated in COPD samples were related to the neutrophilic inflammatory response and TNF-α activation of the NF-κB signaling pathway. In RNA-seq, immune infiltration analysis showed neutrophils were upregulated in COPD lung tissue. We combined data from differential and modular genes and identified 51 differential genes associated with neutrophilic inflammation. Using MR analysis, 6 genes were explored to be causally associated with COPD. Meanwhile, 11 hub genes were identified by PPI network analysis, and all of them were upregulated. qRT-PCR experiments validated 9 out of 11 genes in peripheral blood leukocytes of COPD patients. Furthermore, 5 genes negatively correlated with lung function in COPD patients. Finally, a network of transcription factors for NAMPT and PTGS2 was constructed.ConclusionThis study identified nine novel hub genes related to the neutrophilic inflammation in COPD, and two genes were risk factors of COPD, which may serve as potential biomarkers for the clinical severity of COPD.
Insights into maternal and neonatal anti-Ro/SSA antibodies: implications on pregnancy and neonatal health
Authors: Al Emadi Samar , Satti Eman , Hadwan Nawal 
Published: May 2024

IntroductionThe presence of anti-Ro/SSA antibodies is associated with an increased risk of adverse maternal and neonatal outcomes in patients with autoimmune rheumatic diseases. We evaluated the rate of adverse maternal and neonatal outcomes in a cohort of pregnant women with positive anti-Ro/SSA antibodies in Qatar and explored the significance of neonatal anti-Ro/SSA antibodies.MethodsThis retrospective observational study was conducted at the largest tertiary institute in Qatar between July 2016 and January 2021. The study included pregnant women with confirmed anti- Ro/SSA positivity who were consistently followed to evaluate maternal and fetal complications.ResultsOne-hundred-thirty-two pregnancies from 79 women were included in the analysis. Anti-Ro/SSA positivity was observed in all pregnancies, whereas anti-LA/SSB positivity only in 23.5% of pregnancies. Of the 132 pregnancies, 99 (75%), 27 (20%), and 6 (4.6%) resulted in live birth, miscarriage, and intrauterine fetal demise (IUFD), respectively. Among the 99 live births, serology testing for anti-Ro/SSA was performed on 84 neonates, of which only 45 were positive. Neonates born to mothers with primary SS and rheumatoid arthritis (RA) had higher median antibody titers (240 IU/ml) than those born to mothers with systemic lupus erythematosus (SLE) (89.5 IU/ml)). The rheumatic diseases (SS, RA, or SLE) showed no significant correlation with adverse pregnancy and fetal outcomes. Congenital heart block (CHB) was recorded in only two infants (2%), and one infant had neonatal lupus (1%). Interestingly, CHB was only observed in previously asymptomatic women who were subsequently diagnosed with SS. Most women (85.9%) were treated with hydroxychloroquine throughout pregnancy. These women had lower rates of miscarriage and neither of their infants presented with CHB.ConclusionMiscarriage is the most common adverse outcome reported in this cohort. The incidence of CHB was among asymptomatic carriers only. Nevertheless, hydroxychloroquine use seems to lower the vulnerability to these adverse events. However, these findings need to be validated in larger controlled cohorts. This study is one of few to report results on neonatal anti-Ro/SSA antibody testing.