bluuebunny/crossref_metadata_2025_split huggingface dataset:
An international urogynecological association (IUGA)/international continence society (ICS) joint report on the terminology for reporting outcomes of surgical procedures for pelvic organ prolapse
Authors: Toozs‐Hobson Philip , Freeman Robert , Barber Matthew , Maher Christopher , Haylen Bernard , Athanasiou Stavros , Swift Steven , Whitmore Kristene , Ghoniem Gamal , de Ridder Dirk 
Published: April 2012

AbstractIntroduction and HypothesisStandardized terminology has yet to be developed for reporting the outcomes for surgery for pelvic organ prolapse (POP).MethodsThis report combines the input of the Terminology and Standardization Committees of the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a joint Working Group on this topic, as well as expert external referees. The aim was to present a standardized terminology for the definitions of surgery and propose a structure for reporting the outcomes of surgical procedures for POP. An extensive drafting and review process was undertaken, as well as open review on both IUGA and ICS websites.ResultsA terminology report was developed outlining the recommended structure for reporting outcomes of surgical trials involving POP. This document does not define success and failure. The report includes patient‐reported subjective and objective outcomes to enable researchers to report on their results and compare them with other studies.ConclusionsA consensus‐based method for standardizing terminology for reporting outcome measures of POP surgery was developed to aid clinicians working in this area of research. Neurourol. Urodynam. 31:415–421, 2012. © 2012 Wiley Periodicals, Inc.
Stress urinary incontinence and quality of life: A reliability study of a condition‐specific instrument in paper and web‐based versions
Authors: Sjöström M. , Stenlund H. , Johansson S. , Umefjord G. , Samuelsson E. 
Published: April 2012

AbstractAimsQuality of life is an important outcome measure in studies of urinary incontinence. Electronic collection of data has several advantages. We examined the reliability of the Swedish version of the highly recommended condition‐specific quality of life questionnaire International Consultation on Incontinence Modular Questionnaire‐Lower Urinary Tract Symptoms Quality of Life (ICIQ‐LUTSqol), in paper and web‐based formats in women with stress urinary incontinence.MethodsWomen aged 18–70 years, with stress urinary incontinence at least once weekly, were recruited via the project's website and answered the ICIQ‐LUTSqol questionnaire. Respondents completed either the paper version twice (n = 78), or paper and web‐based versions once each (n = 54). The ICIQ validation protocol was followed.ResultsThe mean interval between answers was 18.1 (SD = 3.1) days in the paper versus paper setting and 15.0 (SD = 7.8) days in the paper versus web‐based setting. Internal consistency was excellent, with Cronbach's alpha coefficients of 0.87 for the paper version and 0.86 for the web‐based version. There was a high degree of agreement of overall scores with intraclass correlations in the paper versus paper and paper versus web‐based settings: 0.95 (P < 0.001) and 0.92 (P < 0.001), respectively. The mean of each individual item's weighted kappa value was 0.61 in both settings.ConclusionsThe questionnaire is reliable in women with stress urinary incontinence, and it can be used in either a paper or a web‐based version. Neurourol. Urodynam. 31:1242–1246, 2012. © 2012 Wiley Periodicals, Inc.
Patients with Fanconi anemia and AML have different cytogenetic clones than de novo cases of AML
Authors: Rochowski Andrzej , Olson Susan B. , Alonzo Todd A. , Gerbing Robert B. , Lange Beverly J. , Alter Blanche P. 
Published: April 2012

AbstractSpecific cytogenetic clones might distinguish patients with unrecognized Fanconi anemia (FA) who present with acute myeloid leukemia (AML) from those with sporadic AML. Cytogenetic reports in literature cases of FA and AML were compared with de novo cases enrolled on CCG‐2961. Gain of 1q, gain of 3q, monosomy 7, deleted 7q, gain of 13q, and deleted 20q were more frequent in FA AML; t(8;21), trisomy 8, t(9;11), t(6;9), and inversion 16 were exclusive to de novo AML cases. Observation of the FA AML cytogenetic clonal patterns should raise suspicion of an underlying leukemia predisposition syndrome and influence management. Pediatr Blood Cancer 2012; 59: 922–924. Published 2012. This article is a U.S. Government work and is in the public domain in the USA.
Dual testing with QF‐PCR and karyotype analysis for prenatal diagnosis of chromosomal abnormalities. Evaluation of 13 500 cases with consideration of using QF‐PCR as a stand‐alone test according to referral indications
Authors: Papoulidis Ioannis , Siomou Elisavet , Sotiriadis Alexandros , Efstathiou George , Psara Anastasia , Sevastopoulou Eirini , Anastasakis Eleftherios , Sifakis Stavros , Tsiligianni Theodora , Kontodiou Maria , Malamaki Christine , Tzimina Maria , Petersen Michael Bjorn , Manolakos Emmanouil , Athanasiadis Apostolos 
Published: April 2012

ABSTRACTObjectiveEvaluate the results obtained from Quantitative Fluorescent (QF)‐PCR and conventional karyotype analysis to determine the advantages and disadvantages of dual testing in prenatal diagnosis.MethodsFrom 1 June 2006 to 1 June 2010, dual testing by QF‐PCR and karyotype analysis was performed in 13 500 prenatal samples. The rates of concordant results between the two methods were evaluated and the rates of clinically significant chromosomal abnormalities undetected by QF‐PCR were assessed.ResultsAbnormal karyotype was found in 320 out of 13 500 cases (2.37%, 95% confidence interval (CI) 2.11–2.63%). From these, QF‐PCR did not detect the abnormality in 70 cases (0.52%, 95% CI 0.4–0.64%), whereas 34 had a high/unknown risk of adverse outcome (0.25%, 95% CI 0.17–0.33%). By selectively applying dual testing only at cases with ultrasound findings and/or genetic history, 13 cases of high/unknown risk would have been missed (0.1%, 95% CI 0.05–0.15%).ConclusionSelective dual testing is expected to achieve a serious beneficial economical outcome and reduce parental anxiety produced by ambiguous cytogenetic findings. However, the percentage of 0.1% undetected clinically significant abnormalities cannot be ignored. A suggestion would include the offering of a choice to the pregnant women, undergoing prenatal screening, by informing them about different approaches and various complications. © 2012 John Wiley & Sons, Ltd.
Particle‐size‐dependent properties of sulfonated polystyrene nanoparticles
Authors: Hazarika Mousumi , Malkappa Kuruma , Jana Tushar 
Published: April 2012

AbstractThe influence of sulfonation reaction time, temperature and the parent polystyrene (PS) particle size on the degree of sulfonation (DS), ion exchange capacity (IEC), morphology and glass transition temperature (Tg) of sulfonated polystyrene (SPS) particles was investigated. A longer reaction time (ca 2 h) at 40 °C and a smaller particle size resulted in SPS particles with a high DS. It was found that a larger PS particle size did not readily yield SPS particles with a high DS even with a longer reaction time. Contrary to the popular belief in the literature that a higher DS ensures a high IEC, we observed that the proportionality of IEC to DS is primarily controlled by the SPS particle size. Larger IEC values were obtained for larger particles rather than smaller ones despite their similar DS, owing to the presence of strong interactions between − SO3H groups within the particles in the latter case which restricts the availability of free H+ for ion exchange. The SPS particles displayed a core‐shell morphology in which the outer shell appeared because of sulfonation on the PS. The DS value and the SPS particle size significantly influenced the shell thickness and thereby the morphology of the SPS particles. Copyright © 2012 Society of Chemical Industry
Polycrystalline silicon PV modules performance and degradation over 20 years
Authors: Polverini Davide , Field Michael , Dunlop Ewan , Zaaiman Willem 
Published: April 2012

ABSTRACTThe presented paper reports the results of the experimental work performed at the European Solar Test Installation, using an array of 70 polycrystalline silicon photovoltaic (PV) modules by the same manufacturer. After almost 20 years of continuous outdoor exposure, the modules were subjected to a comprehensive indoor test plan; in particular, electrical performance measurements were performed, together with a detailed visual analysis. It was also possible to perform a comparison between final and initial data (in particular IV characteristics): module average performance decay is 4.42% for the whole period. Degradation mechanisms, together with their effect on module lifetime, were also analyzed. Results of such a measurement exercise clearly show how PV device reliability over decades can guarantee safe investments, for the benefit of all PV users and stakeholders. The authors are currently installing the modules for further 20 years of outdoor exposure. Copyright © 2012 John Wiley & Sons, Ltd.
Prospects for the biological control of Tuta absoluta in tomatoes of the Mediterranean basin
Authors: Urbaneja Alberto , González‐Cabrera Joel , Arnó Judit , Gabarra Rosa 
Published: April 2012

AbstractSince its detection in the Mediterranean basin at the end of 2006 and later in other European countries, the South American tomato pinworm, Tuta absoluta (Meyrick), has become a serious threat to tomato crops. In newly infested areas, it is especially problematic during the first years of its presence. Nevertheless, after 2–3 years, the incidence of T. absoluta has become less severe in certain areas. There are several factors contributing to this decline, such as the increase in growers' knowledge of pest behaviour and biology and the correct application of integrated pest control strategies. The impact of opportunistic native natural enemies (fortuitous biological control) should be considered as one of the key factors in this decline. In this review, available information on indigenous natural enemies is updated, and the current pest management approaches used against T. absoluta are addressed. Finally, future scenarios for biological control of this pest are discussed. Copyright © 2012 Society of Chemical Industry
Seprafilm® adhesion barrier: (1) a review of preclinical, animal, and human investigational studies
Authors: Diamond Michael P. , Burns Ellen L. , Accomando Beverly , Mian Sadiqa , Holmdahl Lena 
Published: April 2012

AbstractThe aim of this study was to provide a single site resource for investigators, clinicians, and others seeking preclinical, animal, and human investigational studies concerning the postsurgical, anti-adhesion barrier Seprafilm™ (Genzyme Corporation, Cambridge, MA). All published preclinical, animal, human extra-abdominal research as of July 2011 have been summarized and included in this document. Searches of Medline and EMBASE Drugs and Pharmaceuticals databases were conducted for original preclinical, animal, and human extra-abdominal studies involving Seprafilm. Preclinical, animal, and extra-abdominal human investigational studies are the study selection for this manuscript. Intraabdominal use is discussed in the accompanying manuscript. Data extraction includes systematic manuscript review. Summary of preclinical, animal, and extra-abdominal human investigational use of Seprafilm by surgical discipline were gathered for data synthesis. The clinical use of Seprafilm, which was approved by the FDA for intra-abdominal procedures, is supported by preclinical and animal studies relating to general surgical and obstetrical/gynecological applications. Findings from preclinical, animal, and human investigational studies at other sites throughout the body raises the potential for additional human clinical trials to assess efficacy and safety following surgical procedures at non-abdominal locations.
Degradation of Phytosterols During Near‐Ambient Drying of Rapeseeds in a Thick Immobile Layer
Authors: Gawrysiak‐Witulska Marzena , Rudzińska Magdalena 
Published: April 2012

AbstractThe effect of the drying method applied and subsequent rapeseed storage on changes in phytosterols was determined. After harvest, rapeseeds were dried by the near‐ambient method in a thick immobile layer of 2 m and using air heated to a temperature of 60, 80 and 100 °C. Analyses of phytosterol contents were performed immediately after drying and after 6 and 12 months of storage at a temperature of 10 ± 2 °C. Results showed a significant effect of drying conditions, cultivar‐specific differences and storage time on the contents of phytosterols. Near‐ambient drying of seeds resulted in a reduction in total sterol contents by 6–20 %, while for drying with hot air it was by 14–40 %. The level of sterols decreased by 13–18 % after a 1 year storage of seeds dried by the near‐ambient methods. A reduction in 12–22 % in sterols for seeds dried by high temperature occurred after 1 year of storage.
On the response of convectively unstable flows to oscillatory forcing with application to liquid sheets
Authors: Barlow N. S. , Weinstein S. J. , Helenbrook B. T. 
Published: April 2012

AbstractThe complete integral solution is found for the convectively unstable and oscillatory-forced linear Klein–Gordon equation as a function of spatial variable, $x$, and time, $t$. A comparison of the integral solution with series solutions of the Klein–Gordon equation elucidates salient features of both the transient and long-time spatially growing solutions. A rigorous method is developed for identifying the key $x/ t$ rays associated with saddle points that can be used to characterize the transition between transient temporally growing and long-term spatially growing waves. This method effectively combines the procedure given by Gordillo & Pérez-Saborid (Phys. Fluids, vol. 14, 2002, pp. 4329–4343) for determining the $x/ t$ ray at which the forced spatial growth response affects the observed waveform and competes with the transient response, with an established methodology for identifying the leading and trailing edge rays of an impulse response. The method is applied to a linearized system describing an oscillatory-forced liquid sheet and asymptotic predictions are obtained. Series solutions are used to validate these predictions. We establish that the portion of the solution responsible for spatial growth in the signalling problem is correctly identified by Gordillo & Pérez-Saborid (Phys. Fluids, vol. 14, 2002, pp. 4329–4343), and that this interpretation is in contrast with the classical literature. The approach provided here can be applied in multiple ways to study a convectively unstable oscillatory-forced medium. In cases where numerical or series solutions are readily available, the proposed method is used to extract key features of the solution. In cases where only the forced long time behaviour is needed, the dispersion relation is used to extract: (i) the time required to see the forced solution; (ii) the amplitude, phase and spatial growth of the forced solution; and (iii) the breadth of the transient.
Alternative proofs of four stability properties of rigid-link manipulators under PID position control
Authors: Kikuuwe Ryo 
Published: April 2012

SUMMARYThis paper presents new proofs of four stability properties (semiglobal strict passivity, semiglobal asymptotic stability, semiglobal input-to-state stability, and semiglobal uniform ultimate boundedness with an arbitrarily reducible ultimate bound) of a rigid-link manipulator under proportional-integral-derivative (PID) position control. The proofs employ a strict Lyapunov function and a novel parameterization to provide four inequality conditions for the stability properties. In those inequalities, arithmetic operations on physical quantities are physically consistent if the joints are all revolute or all prismatic. A gain selection procedure is presented by which the ultimate bounds of velocity error, position error, and its integral can be independently designed.
Carbapenem-susceptible Acinetobacter baumannii carrying the ISAba1 upstream blaOXA-51-like gene in Porto Alegre, southern Brazil
Authors: PAGANO M. , MARTINS A. F. , MACHADO A. B. M. P. , BARIN J. , BARTH A. L. 
Published: April 2012

SUMMARYOver the last decade, Acinetobacter baumannii resistant to carbapenems has emerged in many medical centres and is commonly associated with high morbidity and mortality. We investigated potential mechanisms contributing to antimicrobial resistance of 58 clinical isolates of A. baumannii collected during a prolonged city-wide outbreak in five different hospitals in southern Brazil. The integrase gene was detected in 51 (87·9%) isolates of which 36 harboured class 2 integrons alone and 14 had both class 1 and 2 integrons; all carbapenem-resistant isolates displayed class 2 integrons. ISAba1 was found upstream of blaOXA-23-like only in isolates resistant to carbapenems; however, ISAba1 upstream of blaOXA-51-like was present in both susceptible and resistant isolates. This is the first report of a high prevalence of class 2 integrons in A. baumannii in southern Brazil. Moreover, our study suggests that ISAba1/blaOXA-51-like alone is insufficient to confer resistance to carbapenems.
Deciphering how the chromatin factor RCC1 recognizes the nucleosome: the importance of individuals in the scientific discovery process
Authors: Tan Song 
Published: April 2012

The nucleosome repeating unit of chromatin is the target of chromatin enzymes and factors that regulate gene activity in a eukaryotic cell. How the nucleosome is recognized by chromatin enzymes and factors is poorly understood, even though such interaction is fundamental to gene regulation and chromatin biology. My laboratory recently determined the structural basis for how the RCC1 (regulator of chromosome condensation 1) chromatin factor binds to the nucleosome, including the first atomic crystal structure of a chromatin protein complexed with the nucleosome core particle. I describe here how we developed and investigated structural models for RCC1 binding to the nucleosome using biochemical methods and how we crystallized the 300 kDa complex of RCC1 with the nucleosome core particle. This article highlights the contributions made by key laboratory members and explains our thinking and rationale during the discovery process.
14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites
Authors: Cockcroft Shamshad , Garner Kathryn 
Published: April 2012

PITPs (phosphatidylinositol transfer proteins) are characterized by the presence of the PITP domain whose biochemical properties of binding and transferring PI (phosphatidylinositol) are well studied. Despite their wide-spread expression in both unicellular and multicellular organisms, they remain functionally uncharacterized. An emerging theme is that individual PITPs play highly specific roles in either membrane trafficking or signal transduction. To identify specific roles for PITPs, identification of interacting molecules would shed light on their molecular function. In the present paper, we describe binding partners for the class IIB PITP RdgBβ (retinal degeneration type Bβ). RdgBβ is a soluble PITP but is unique in that it contains a region of disorder at its C-terminus following its defining N-terminal PITP domain. The C-terminus of RdgBβ is phosphorylated at two serine residues, Ser274 and Ser299, which form a docking site for 14-3-3 proteins. Binding to 14-3-3 proteins protects RdgBβ from degradation that occurs at the proteasome after ubiquitination. In addition to binding 14-3-3, the PITP domain of RdgBβ interacts with the Ang II (angiotensin II)-associated protein ATRAP (Ang II receptor-associated protein). ATRAP is also an interacting partner for the AT1R (Ang II type 1 receptor). We present a model whereby RdgBβ functions by being recruited to the membrane by ATRAP and release of 14-3-3 from the C-terminus allows the disordered region to bind a second membrane to create a membrane bridge for lipid transfer, possibly under the control of Ang II.
Reading Vocabulary Knowledge and Deafness
Authors: Paul Peter V. 
Published: April 2012

Abstract
With respect to reading vocabulary knowledge and deafness, this article addresses two broad questions: (1) Why is vocabulary knowledge related to reading comprehension ability? (2) How is reading vocabulary (i.e., word meanings) acquired? The article argues that the answers to these questions are best addressed by a vocabulary acquisition model labeled the knowledge model. In essence, this model asserts that both breadth and depth of vocabulary knowledge are critical. It is necessary to teach vocabulary, especially to poor readers, who are not likely to derive many word meanings from the use of context during natural or deliberate reading situations. On the basis of theoretical and research syntheses, the article offers implications for vocabulary instruction for deaf children and adolescents.
An Empirical Spatial Model of Congressional Campaigns
Authors: McCarty Nolan M. , Poole Keith T. 
Published: April 2012

Testing and estimating formal models of political behavior has not advanced as far as theoretical applications. One of the major literatures in formal theory is the spatial model of electoral competition which has its origins in the work of Black (1948) and Downs (1957). These models are used to make predictions about the policy positions candidates take in order to win elections. A lack of data on these candidate positions, especially challengers who never serve in Congress, has made direct testing of these models on congressional elections difficult.Recently, researchers have begun to incorporate campaign finance into the standard Downsian model. These models of position-induced contributions examine the tradeoff that candidates make between choosing positions favorable to interest group contributors and positions favorable to voters. A major premise of these models is that interest group contributions are based on the policy positions of candidates. This has been borne out empirically in the case of incumbents, but not challengers.To test key hypotheses of these models, we develop a simple spatial model of position-induced campaign contributions where the PAC's decision to contribute or abstain from each race is a function of the policy distance between the PAC and the candidates. We use data from political action committee contributions in order to estimate the locations of incumbents, challengers and PACs. Our model reliably estimates the spatial positions as well as correctly predicts nearly 74 percent of the contribution and abstention decisions of the PACs. Conditional upon making a contribution, we correctly predict the contribution in 94 percent of the cases. These results are strong evidence for position-induced campaign contributions. Furthermore, our estimates of candidate positions allow us to address issues of platform convergence between candidates.
The Structure of Mathematical Experience According to Jean Cavaillès
Authors: CORTOIS PAUL 
Published: April 2012

Abstract
In this expository article one of the contributions of Jean Cavailles to the philosophy of mathematics is presented: the analysis of ‘mathematical experience’. The place of Cavailles on the logico-philosophical scene of the 30s and 40s is sketched. I propose a partial interpretation of Cavailles's epistemological program of so-called ‘conceptual dialectics’: mathematical holism, duality principles, the notion of formal contents, and the specific temporal structure of conceptual dynamics. The structure of mathematical abstraction is analysed in terms of its complementary dimensions: paradigmatic generalization (domain extension, descriptive definitions, creative role of the symbolism…) and thematic reflexivity of concepts (promotion of operations to objects of a higher type).