bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Development of a Cultural-based Questionnaire for Drug Use Prevention Programs for Adolescents: A Delphi Study
Authors: Tahlil Teuku , Hadi Nurul , Maulina . , Marlina . 
Published: February 2025

Objective
This study aimed to identify a valid and cultural-based questionnaire for drug use prevention programs for adolescents.

Methods
The study used a three-round Delphi technique. A total of 21 participants with knowledge and experiences in community nursing (11 nurses) and education for junior high school students (11 teachers) in Aceh Province, Indonesia, were included. For the first round, focus group discussions were conducted. For the second round, participants were asked to indicate their levels of agreement and provide their comments on the proposed questionnaire. For the third round, participants were instructed to indicate their level of agreement with the final version of the developed questionnaire. The consensus was defined based on the percent agreement.

Results
Initially, 64 questions for four domains (knowledge = 14 items, attitude = 29 items, intention = 9 items, behaviors = 12 items) were developed based on the FGDs and literature review. Finally, the four domains and 43 questions (knowledge = 14 items, attitude = 12 items, intention = 9 items, behaviours = 8 items) were supported by the group panels as the final instrument for the evaluation of drug use prevention programs for adolescents in schools.

Conclusion
Expert panels validated the content of the questionnaire for the drug use prevention programs in Indonesia. Nonetheless, further analysis and implementation of the instrument are required to identify the accuracy of the instrument.
Pleiotropic Leukemia Inhibitory Factor Encapsulated in DODAB:MO Liposomes for Multiple Biomedical Applications
Authors: Pinho Vanessa , Fernandes Mário , Machado Raúl , Oliveira Maria Elisabete C.D. Real , Gomes Andreia C. 
Published: February 2025

Introduction:
The development of novel drug carriers is invaluable to maximize therapeutic
efficiency and improve specificity. Dioctadecyl-dimethylammonium bromide (DODAB):
monoolein (MO) (1:2) liposomes exhibit non-lamellar phases in their core that improve the encapsulation
ability of both hydrophobic and hydrophilic molecules. This study explores the use of this
nanosystem for the therapeutic delivery of cytokines, specifically of leukemia inhibitory factor
(LIF). Nanocarriers can overcome the drawbacks of direct cytokine administration, like poor bioavailability.

Methods:
DODAB:MO (1:2) liposomes were produced by lipid film hydration, followed by extrusion,
and used for encapsulating 0.125 and 0.25 μM LIF. The produced nanoparticles were characterized
in terms of size and zeta potential, FTIR and STEM. LIF was quantified with an optimized
Bradford method to determine encapsulation efficiencies, drug loading, and release profile. Cytotoxicity
was assessed by hemolysis, and mouse myoblasts were used to validate bioactivity in
vitro.

Results:
Neither the extrusion nor the protein incorporation steps promoted significant alterations
in cytokine structure. LIF-containing liposomes DODAB (1:2) nanosystem were small
(~200-300nm), positively charged (~50-60mV), non-toxic, and stable at physiological pH. Biophysical
characterization identified liposomal formulation of 200 μM DODAB:MO (1:2) at 0.25
μM as the most efficient system. The bioactivity analysis showed an increase of ~20% in cell proliferation
after 48h of incubation when compared to free mLIF. Also, the LIF-containing DODAB:
MO (1:2) liposomal formulation, when exposed to serum, revealed a capacity to protect its cargo
for up to 6 h.

Conclusion:
The DODAB:MO (1:2) nanosystem was found to be efficient for cytokine delivery,
stabilizing mLIF, and promoting its bioactivity with multiple applications.
Conexiones que importan: el papel del apoyo social en la relación entre estrés laboral y salud mental de las científicas españolas
Authors: Sánchez-Holgado Patricia , Rodríguez-Contreras Laura , Xiang Yangjian 
Published: February 2025

El estrés laboral es un factor que impacta negativamente en la salud mental. El objetivo de este trabajo es analizar los factores que pueden tener un efecto en la salud mental de las mujeres que trabajan en la ciencia y la investigación científica en España. Se examina la relación entre estrés laboral y salud mental, así como la influencia del apoyo social y la edad. Para ello se llevó a cabo una encuesta a 231 participantes, que se analizó con un enfoque descriptivo y un análisis de moderación y de mediación utilizando regresión lineal múltiple. Los resultados revelaron que existe una correlación estadísticamente significativa en la relación entre el estrés y la salud mental. Aunque no se encontró un efecto de moderación del apoyo social entre el estrés y la salud mental, los hallazgos indicaron que el apoyo social de una persona especial sí actuó como un mediador relevante. Aquellas personas que recibieron este tipo de apoyo experimentaron una reducción en su nivel de estrés y una mejora en su salud mental. En este sentido, se hace necesario mejorar las políticas laborales basadas en el apoyo, en la distribución equitativa de las tareas de cuidado y las políticas institucionales que contribuyan a la creación de un entorno más favorable a la salud mental óptima.
Religious Humanism: Basic Education of Javanese Society
Authors: Wahyudi M. Agus , Maftukhin Maftukhin , Khamami Akhmad Rizqon 
Published: February 2025

Humanism is a Western philosophical thought that believes that humans have high values and positions and are at the center, or are referred to as anthropocentric. This kind of thinking has both positive and negative impacts. The positive impact is to prioritize human values, while the negative impact is that humans do not need God in their lives because they believe in their own efforts. Javanese people are known for their friendly, humanist and religious people. Religious humanism is a feature of the Javanese model of religious behavior. RMP. Sosrokartono is one of the figures from Java whose thoughts indirectly include human values that characterize the religious behavior of the Javanese people. The method in this research is a qualitative type. The data to be analyzed is in the form of primary data, namely the thoughts of RMP. Sosrokartono and secondary data, namely supporting data related to research. The aim of the research is to reveal the values religious humanism RMP. Sosrokartono and how it is implemented on the religious behavior of the Javanese people. The results of this study are that there are RMP. Sosrokartono whose name is ilmu kantong bolong, ilmu kantong, ilmu kantong kosong, and lmu sunyi in which there are values of religious humanism
Identifikasi Akhlak Mahmudah dalam Pendidikan Agama Islam (Kajian Kitab Hidayah al-Salikin)
Authors: Soleh Warissuddin , Vahlepi Sahrizal , Mustofa Ady Muh. Zainul 
Published: February 2025

The purpose of Islamic education is to form a mahmudah morality. The formula for the moral provisions of mahmudah occupy an important position. There are many formulas about mahmudah morality which are narrative in nature and often overlap between one meaning and the other meaning. This study examines the identification of mahmudah morality in Islamic religious education through the study of the book Hidayah al-Salikin by Abdul Samad al-Falimbani. The focus of the research is the fifth chapter of the book. The research approach is qualitative with library research methods. Data analysis techniques using Miles and Huberman data analysis models. The results of the research are identified ten mahmudah morality which are very relevant to the formulation of the noble character education of Islamic religion. The Ten mahmudah morality described in the Book of Hidayah al-Salikin are: repentance, khauf, zuhud, be patient, thanksgiving, sincerity, tawakal, mahabbah, rida, and remembering death.
Keyword: Moral identification; Mahmudah; Hidayah al-Salikin
The Epistemology of Quraish Shihab’s Interpretation of Poverty in Tafsir Al-Misbah
Authors: Nurin PK. (Indonesia) Moh. Nurun Alan , (Frankfurt, Jerman) Thomas K. Gugler , Ali (Malete, Nigeria) Ali Miqdad , Hamdan (Indonesia) Mila Aulia 
Published: February 2025

This study departs from the interpretation of M. Quraish Shihab on poverty verses. as an effort to verify and validate the truth of the interpretation of poverty in Tafsir Al-Misbah, this study seeks to review the epistemological aspects of Quraish Shihab's interpretation in Tafsir Al-Misbah on poverty verses. This study can be classified as a qualitative study. This research is included in descriptive-analytical research. Called descriptive because this study will review and analyze the Quraish Shihab Interpretation of the verses of Poverty in Tafsir Al-Misbah. The results of this study are, First, the source of interpretation, the interpretation set forth in Tafsir Al-Misbah, especially with regard to the verses of Shikinan in the Qur 'an, can not be separated from the principles that prioritize Sahihic histories and the context of the relationship between one verse and another (read : munasabatul ayat), as well as how the background of the verse then pours out the meaning that is relevant to the context today. Second, Methodology of interpretation, Tafsir Al-Misbah as a contemporary tafsir work tends to use analytic methodology (tahlily) in revealing the message and meaning contained in a verse. More specifically in the context of the poverty verses of Quraish Shihab as a mufassir it is very visible how the interpretive effort is very thick with cultural and societal literary styles (al-adabi al-ijtima 'i), and the third aspect is the validity of interpretation, with reference to several aspects, coherence, correspondence, and pragmatism. That M. Quraish Shihab's interpretation of the scriptures is very appropriate and has a strong relevance to the phenomenon of poverty that occurs, besides that the interpretation presented is not only pouring meaning in the Qur'an but also presents a problem solver to the phenomenon and reality that occurs. When drawn in the context of M. 's interpretation. Quraish Shihab in the tafsir ofAl-Misbah which specifically discusses the term poverty in the Qur'an can be seen how the consistency of M. Quraish Shihab in interpreting the poorest and his efforts to devise solutions to these realities.
Europa zur Chefsache machen
Authors: Wambach Achim 
Published: February 2025

Abstract
The fundamental challenges that Germany is facing – increasing productivity, combining the transformation to climate neutrality with economic growth, making the economy more resilient – cannot be tackled in large part without Europe. This is in the nature of things: resilience and security of supply cannot be achieved nationally, and reducing emissions is a global task. In addition, key levers are within the EU’s mandate. The new German government should therefore make European economic policy a top priority. German economic policy should take a more European approach.
Biochar Limbah Bubuk Kopi dari UMKM Kopi Tirtoyudo Malang Selatan
Authors: Faradila Razhika , Harsono Soni Sisbudi , Lasari Yuni 
Published: February 2025

Limbah yang dihasilkan dari sebagian besar UMKM kopi di Malang Selatan ini masih belum dimanfaatkan secara optimal, hal ini dapat dilihat dari menumpuknya limbah kopi di sekitar tempat pengolahan. Penelitian ini merupakan inisiasi dari tim peneliti untuk memberikan pengetahuan dan kepercayaan terhadap pelaku UMKM Kopi Tirtoyudo dalam meningkatkan nilai guna Limbah Kopi dan ekonomi sirkular. Secara umum tujuannya memberikan informasi terkait kualitas pembakaran biochar limbah bubuk kopi melalui analisis proksimat dan sosialisai terkait pengolahan limbah kopi menjadi energi alternatif yaitu biochar. Dari penelitian yang dilakukan menghasilkan Biochar Limbah Kopi dengan suhu 500oC memiliki komposisi terbaik dengan nilai kadar air 9,33%, kadar abu 4,08%, pH 9,55, C-Organik 13,15% dan zat terbang 14,55%. Hal ini dikarenakan kopi memiliki komposisi yang baik untuk mengembalikan unsur hara dan dilakukan pengeringan sebelum run-off biochar.Kegiatan penelitian ini diharapkan dapat memberikan wawasan dan keahlian kepada masyarakat khususnya pelaku UMKM Kopi Tirtoyudo di Malang Selatan agar dapat mengembangkan teknologi energi terbarukan biochar dari limbah bubuk kopi (Spent Coffee Ground) menjadi alternatif penggunaan bahan bakar yang lebih efisien, murah dan ramah lingkungan.
A comparative study of the efficacy of potent topical corticosteroids per se versus combination of potent topical corticosteroids with fractional CO2 laser in the management of vitiligo vulgaris
Authors: Ninama Kishan , Mahajan Rashmi , Baxi Disha , Patil Raveena Sanjay , Marfatia Yogesh 
Published: February 2025

Objectives:
The study aimed to compare the efficacy of two treatment modalities in vitiligo vulgaris that is – potent topical corticosteroid (betamethasone-dipropionate lotion 0.05%) with FrCO2 laser versus Potent topical corticosteroid (PTS) alone, and to observe side effects if any.

Material and Methods:
Sixty cases with stable vitiligo (vitiligo vulgaris including focal vitiligo) >12 years of age with <27% body surface area were included in the study. The Institutional Ethics Committee approval was taken. After taking consent and clinical photographs, cases were randomly allocated into two groups of 30 patients each: Group A received FrCO2 laser (power-6W, random mode) once a month + twice daily application of PTS (betamethasone dipropionate lotion 0.05%) over patches and Group B applied PTS only twice daily (betamethasone dipropionate lotion 0.05%). The response was assessed at the end of 3 months.

Results:
The mean vitiligo area scoring index (VASI) score at baseline for Group A was 1.17 ± 0.59, and after 3 months was 0.60 ± 0.56. For Group B, the mean VASI at baseline was 0.87 ± 0.35 and after 3 months was 0.63 ± 0.50. The p value of group B was 0.003 and for group A was 0.001. Even though the reduction in mean VASI was statistically significant in both groups, Group A showed a better response. Group A showed good to excellent response in 16.67% while Group B only cases in 3.3%. This suggests that the addition of FrCO2 to steroids may provide superior repigmentation.

Conclusion:
The addition of FrCO2 laser to topical corticosteroids offers a safe and promising approach and can be considered in patients who are unresponsive to other treatment modalities.
АНАЛИЗ КАДРОВОГО ПОТЕНЦИАЛА ГОСУДАРСТВЕННОЙ ГРАЖДАНСКОЙ СЛУЖБЫ: РЕГИОНАЛЬНЫЙ АСПЕКТ
Authors: Петухова Е.А. 
Published: February 2025

В статье проведён анализ развития региональной государственной гражданской службы за 2019–2023 гг., выявлены основные проблемы, определены векторы укрепления кадрового потенциала и пути развития человеческого капитала госслужбы.
Introduction. The state is facing the important task of providing high-quality training for civil servants at all levels. To date, the civil service has developed a strong competence in personnel administration, but at the same time, there is an obvious need for a new approach to human potential management and development, and also for the formation of a new culture, which would be attractive primarily to young people. The purpose of the work is to identify the development trends and prospects of the human resource potential in the state civil service of the Republic of Mari El based on its analysis and assessment. Results. The analysis was carried out on the basis of monitoring the development of state and municipal services, as well as the award policy implementation in the Republic of Mari El over the past five years (2019–2023). At present, the civil service has a “woman’s face”: on average, the percentage of female civil servants is 74 %, and the proportion of men is 26 %. Another trend that has been revealed shows that every year the number of employees aged 41–60 increases, the number of young people decreases, and the rate of employees over the age of 60 remains stable. This may indicate that the institution of state civil service is becoming less attractive to young people. Staff members who have two or more higher education degrees make up 26 % of the total number of employees. Conclusion. The trends identified in the staff composition of civil service in the Republic of Mari El during the monitoring are also characteristic of the state civil service of the Russian Federation in general. There is a need to review the approaches to the implementation of personnel policies in public authorities in order to preserve the existing human resource potential and attract qualitatively new human capital to the civil service.
РИНЦИПЫ РАЗВИТИЯ КАДРОВОГО ОБЕСПЕЧЕНИЯ ПРЕДПРИЯТИЯ ОПК СПЕЦИАЛИСТАМИ УПРАВЛЕНЧЕСКОГО ПРОФИЛЯ ДЛЯ ОСУЩЕСТВЛЕНИЯ ДИВЕРСИФИКАЦИИ
Authors: Махова А.В. , Мищенкова О.В. 
Published: February 2025

Представлен сравнительный анализ определений понятия «кадровое обеспечение». Систематизированы принципы развития кадрового обеспечения предприятия оборонно-промышленного комплекса специалистами управленческого профиля для осуществления диверсификации. Определён основополагающий принцип, позволяющий не только использовать современные научные разработки, но и разрабатывать новые подходы организационно-экономического управления использования продукции двойного назначения.
Introduction. The dramatic changes occurring due to the reduction and stabilization of the state defence order, along with the need for diversification at enterprises of the military-industrial complex, initiate changes in the system of staffing the enterprises with management specialists. The purpose of the work is to study the principles that influence the formation and the state of management specialist staffing for implementing diversification, as well as to identify the fundamental principle enabling defence industry enterprises to adapt to the requirements of the market economy. Results. The analysis of the experience of domestic defense industry enterprises engaged in production diversification has shown that the staffing policy in relation to management specialists is based on a number of principles including those of scientific (innovative) character, systematicity, planned character, specificity, comprehensiveness, optimization nature, continuity, methodicalness, efficiency, and competence. Diversified production requires new specialists equipped with competencies in various fields of knowledge, often at the intersection of different specialties. This demands personnel capable of proactive work, i.e., highly qualified staff who are able to ensure the efficiency of management by integrating the accumulated practical experiences. A certain amount of experience in training highly qualified personnel for defense industry enterprises has been acquired by Kalashnikov Izhevsk State Technical University. Conclusion. The formation of the system of staffing defense industry enterprises with management specialists and modifications within the system should be carried out in accordance with a multi-principles approach, which makes it possible to present a mechanism for developing the staffing of defense industry enterprises with management specialists for implementing diversification in a holistic manner.
МАКРОСЕИСМИЧЕСКИЕ ПРОЯВЛЕНИЯ ШАТОЙСКОГО ЗЕМЛЕТРЯСЕНИЯ 12 ДЕКАБРЯ 2020 г. С М=4.7
Authors: Асманов О.А. , Адилов З.А. , Бадаев С.В. 
Published: February 2025

В статье приводятся инструментальные данные и описание макросейсмических проявлений землетрясения с Ms=4.7, произошедшего 12 декабря 2020 г. на территории Шатойского района Чеченской Республики. Приведен анализ решения для эпицентра по данным ФИЦ ЕГС РАН и международных сейсмологических служб (ISC, Великобритания; NEIC, США; TIF, Грузия; IDC, Австрия). Построена карта изосейст Шатойского землетрясения и выполнена оценка интенсивности сотрясений в населенных пунктах в баллах шкалы MSK-64.
The article provides instrumental data and a description of the macroseismic manifestations of the earthquake with Ms = 4.7 that occurred on December 12, 2020 in the Shatoisky district of the Chechen Republic. An analysis of the solution for the epicenter is provided based on the data of the Federal Research Center of the Geophysical Survey of the Russian Academy of Sciences and international seismological services (ISC, UK; NEIC, USA; TIF, Georgia; IDC, Austria). A map of isoseisms of the Shatoy earthquake was constructed and the intensity of shaking in populated areas was assessed in MSK-64 scale points.
RESEARCH OF THE VEGETATION COVER OF THE GREATER CAUCASUS HIGHLANDS BASED ON GIS TECHNOLOGIES AND REMOTE SENSING
Authors: Gasimova U.Sh. 
Published: February 2025

Relevance: In the article, the vegetation spread in the highlands of the Greater Caucasus Mountains within the Republic of Azerbaijan was analyzed. Although the role of natural factors in changing the vegetation of high mountainous areas is great, the use of natural fodder in animal husbandry has caused an increase in anthropogenic effects. The mentioned factors have led to the decrease and degradation of vegetation over time. Vital factors that affect degradation of soil and vegetation cover are overgrazing and animal husbandry. Alpine and subalpine landscapes of our investigation area are basic summer pastures of our republic. Research methods: During the research, we used modern methods to analyze and compare satellite images of the area we studied from 2000 and 2023. Results of the work and discussion: As a result of the research, it was determined that the area of places with dense vegetation, their types and composition, as well as the area of places showing water basins, has decreased.
Актуальность. В статье проанализировано распространение растительности в высокогорьях Большого Кавказа на территории Азербайджанской Республики. Хотя роль природных факторов в изменении растительности высокогорных территорий велика, использование натуральных кормов в животноводстве привело к усилению антропогенного воздействия. Указанные факторы с течением времени привели к уменьшению и деградации растительности. Жизненно важными факторами, влияющими на деградацию почвенного и растительного покрова, являются чрезмерный выпас скота и животноводство. Альпийские и субальпийские ландшафты территории нашего исследования являются основными летними пастбищами нашей республики. Методы исследования. В ходе исследования были использованы современные методы анализа и сравнения спутниковых снимков изучаемой территории за 2000 и 2023 годы. Результаты работы и обсуждение. В результате исследования установлено, что площадь мест с густой растительностью, ее виды и состав, а также площадь мест с водными бассейнами уменьшились.