bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pendidikan Tentang Hipertensi Dan Pelatihan Menggunakan Alat Tensimeter Digital Bagi Kader Kesehatan Desa Sungai Rangas Tengah
Authors: Saputri Rina , Hakim Ali Rakhman , Mustaqimah Mustaqimah , Savitri Amanda Shelvia , Ujuldah Anisa , Damayanti Aulia , Defitamira Olvi , Sari Rani Normaya , Vania Risma Ananda 
Published: June 2024

Pendahuluan: Hipertensi masih menjadi penyakit yang banyak diderita oleh masyarakat. Penderita hipertensi harus meminum obat secara rutin setiap hari. Salah satu cara untuk mengendalikan kepatuhan minum obat dan kontrol kesehatan penderita hipertensi adalah dengan memaksimalkan peran Kader kesehatan. Kader kesehatan memiliki peran sebagai penyuluh kesehatan di desa. Kader kesehatan harus memiliki pengetahuan dan keterampilan yang cukup agar dapat memberikan informasi yang benar sesuai batas kemampuannya.Tujuan: Tujuan dari pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan tentang penyakit hipertensi dan keterampilan menggunakan alat tensimeter digital yang benar kepada kader kesehatan.Metode: Metode yang digunakan adalah metode pembelajaran kooperatif. Kader diberi pendidikan pengetahuan tentang penyakit hipertensi menggunakan media leaflet dan diberi pelatihan menggunakan alat tensimeter digital yang benar. Peserta dari kegiatan adalah kader kesehatan desa Sungai Rangas Tengah.Hasil: Hasil dari kegiatan ini adalah terjadi peningkatan pengetahuan kader kesehatan tentang penyakit hipertensi. Kader kesehatan mampu memahami isi leaflet hipertensi dan mampu menyampaikan kembali maksud dari leaflet hipertensi. Kader kesehatan mampu menggunakan alat tensimeter digital dengan benar setelah mendapatkan pelatihan.Simpulan: Simpulan dari kegiatan ini yaitu kader kesehatan dapat mengedukasi warga menggunakan media leaflet dan mampu menggunakan alat tensimeter digital dengan benar.
From Research To Manuscript: Pelatihan Penulisan Manuskrip Jurnal Internasional Pada Mahasiswa DIII Farmasi Universitas Muhammadiyah Palangkaraya
Authors: Novaryatiin Susi , Ardhany Syahrida Dian , Feryanto Mohammad , Satria Elga , Azizah Melia , Novianti Vifilia Dwi 
Published: June 2024

Pendahuluan: Pentingnya mempublikasikan hasil penelitian oleh peneliti, terutama mahasiswa, ke dalam jurnal internasional. Akan tetapi, kurangnya pelatihan menyebabkan manuskrip yang dibuat oleh mahasiswa belum memenuhi standar yang diperlukan untuk publikasi. Oleh karena itu, diperlukan pelatihan penulisan manuskrip untuk meningkatkan kemampuan mahasiswa dan menyambut kebijakan penyusunan manuskrip ilmiah sebagai syarat kelulusan. Tujuan: Kegiatan ini bertujuan untuk meningkatkan pengetahuan mahasiswa tentang penulisan manuskrip jurnal internasional.Metode: Metode pengabdian kepada masyarakat ini adalah pelatihan penulisan manuskrip jurnal internasional terhadap 30 peserta, dengan pemberian materi terkait publikasi ilmiah, sistematika penulisan manuskrip yang baik, prosedur publikasi ilmiah pada jurnal internasional, dan cara memilih jurnal.Hasil: Pengukuran target capaian dilakukan dengan pemberian pre-test dan post-test, didapatkan bahwa nilai rata-rata sebesar 58 (pre-test) dan 79 (post-test). Dilakukan analisis lebih lanjut menggunakan IBM SPSS versi 22 dengan uji Wilcoxon, diketahui bahwa 21 peserta mengalami peningkatan nilai dan 9 peserta memiliki nilai pre-test dan post-test yang sama.Simpulan: Dapat disimpulkan bahwa 70% peserta mengalami peningkatan pengetahuan setelah mendapatkan pelatihan. Hasil uji Wilcoxon didapatkan angka P= 0.000 (P< 0.05), yang menunjukkan adanya pengaruh signifikan dari pemberian materi pelatihan penulisan manuskrip jurnal internasional pada mahasiswa DIII Farmasi Universitas Muhammadiyah Palangkaraya.
Edukasi Tentang Persiapan Menyusui Secara Eksklusif Pada Kelompok Ibu Hamil
Authors: Mariana Frani , Yuliantie Putri , Maisarah Maisarah 
Published: June 2024

Pendahuluan: Pemberian ASI sejak dini dan secara eksklusif sangat penting bagi kelangsungan hidup seorang anak karena dapat melindungi dari berbagai penyakit. Penyakit yang rentan dialami dapat berakibat fatal, seperti diare dan pneumonia . Menurut data Riskesdas tahun 2021, sebesar 52,5 % atau hanya setengah dari 2,3 juta bayi berusia kurang dari enam bulan, yang mendapat ASI secara eksklusif di Indonesia, atau menurun 12%, dari angka di tahun 2019. Hal ini, ketersediaan layanan edukasi tentang persiapan menyusui secara eksklusif untuk semua ibu hamil, baik secara tatap muka maupun melalui platform digital sangat diperlukan.Tujuan: Tujuan dari pelaksanaan kegiatan ini adalah meningkatkan pemahaman dan kesadaran ibu hamil untuk bisa berpartisipasi aktif menyusui bayi secara eksklusif setelah bayi lahir sampai usia 6 bulan.Metode: Kegiatan Pengabdian kepada Masyarakat berupa penyuluhan tentang ASI Eksklusif dan persiapan menyusui serta dilanjutkan dengan diskusi. Kegiatan ini diikuti oleh Ibu Hamil dengan jumlah 13 orang.Hasil: Hasil dari kegiatan pengabdian masyarakat ini menunjukan adanya peningkatan pengetahuan ibu hamil sebelum dan setelah dilakukan kegiatan. Hasil kegiatan ini juga, semua ibu hamil setelah melahirkan memiliki keinginan untuk menyusui secara eksklusif sampai usia bayi 6 bulan.Simpulan: Kegiatan pengabdian masyarakat yang telah dilakukan melalui penyuluhan dan diskusi, dapat meningkatkan pengetahuan dan wawasan ibu hamil mengenai pentingnya persiapan menyusui secara eksklusif, sehingga ibu hamil akan berpartisipasi aktif menyusui bayinya secara eksklusif, setelah bayi lahir sampai usia 6 bulan.
OPTIMALISASI PEMBELAJARAN ANALISIS PEMODELAN BANGKITAN PERJALANAN MENGGUNAKAN APLIKASI SPSS PADA MATA KULIAH PERENCANAAN DAN PEMODELAN TRANSPORTASI PRODI S1 SIPIL FAKULUTAS TEKNIK UNIVERSITAS RIAU
Authors: Rizqy Ridho Praksa  , Adiman Edi Yusuf , Putra Benny Hamdi Rhoma 
Published: June 2024

The importance of mastering skills in statistical analysis in the field of transportation planning and modeling has not been supported by learning to use the SPSS application so that the teaching and learning process is not optimal for students of the Civil Engineering Study Program at Riau University. The purpose of this optimization is to provide knowledge to undergraduate students of Civil Engineering, Riau University in order to gain specific skills, namely modeling trip generation using the SPSS application. Optimization method by introducing the SPSS application and making teaching modules in modeling trip generation, Pre Test to find out student knowledge related to the SPSS application, ending with Post Test activities as evaluation material. The results of the Pre Test were 50-60% of students did not know the application, while the Post Test results were 90% of students knew the use of the SPSS application in modeling trip generation well. It is hoped that this optimization will increase knowledge and skills which can later become a plus point in the world of work.
PENINGKATAN KEPATUHAN PELAJAR TERHADAP TATA TERTIB DI SEKOLAH
Authors: Usmita Fakhri , Rinaldi Kasmanto , Hidayati  
Published: June 2024

Kepatuhan merujuk pada kemampuan pelajar dalam mengikuti aturan, norma, dan tata tertib yang telah ditetapkan oleh sekolah. Tata tertib di sekolah adalah pedoman yang mengatur perilaku dan interaksi pelajar, dan memastikan lingkungan belajar yang aman dan produktif. Peningkatan kepatuhan pelajar terhadap tata tertib di sekolah dapat dilakukan dengan menggunakan pendekatan kriminologi yang dapat memberikan wawasan dan strategi yang efektif dalam memahami faktor-faktor yang mempengaruhi pelajar dalam melangar tata tertib serta upaya pencegahannya. Hal ini dapat mencakup pengembangan program pendidikan dan pencegahan untuk remaja, pembentukan komunitas sekolah yang inklusif, peningkatan pengawasan dan pengawasan di lingkungan sekolah, serta penerapan sanksi yang proporsional dan rehabilitatif bagi pelajar yang melanggar tata tertib. Tujuan dilaksanakan kegiatan pengabdian ini yaitu agar membentuk pemahaman pelajar khsuusnya pelajar UPT SMP Negeri 2 Bangkinang Kota mengenai kepatuhan terhadap tata tertib di sekolah beserta dampaknya sehingga diharapkan pelajar mematuhi tata tertib di sekolah. Métode yang dilakukan dalam pengabdian ini adalah dengan melakukan tahap persiapan yang berupa observasi dan tahap pelaksanaan kegiatan pengabdian. Dari hasil yang diperoleh dari pengabdian, para siswa memahami tentang manfaat kepatuhan terhadap tata tertib di sekolah. Para siswa dapat menaati tata tertib yang ada di sekolah dengan lebih baik lagi.
Gypenosides exert cardioprotective effects by promoting mitophagy and activating PI3K/Akt/GSK-3β/Mcl-1 signaling
Authors: Zheng Yizhe , Wei Wei , Wang Yukun , Li Tingting , Wei Yundong , Gao Si 
Published: June 2024

Background
Gynostemma pentaphyllum (Thunb.) Makino, a well-known edible and medicinal plant, has anti-aging properties and is used to treataging-associated conditions such as diabetes, metabolic syndrome, and cardiovascular diseases. Gypenosides (GYPs) are the primary constituents of G. pentaphyllum. Increasing evidence indicates that GYPs are effective at preserving mitochondrial homeostasis and preventing heart failure (HF). This study aimed to uncover the cardioprotective mechanisms of GYPs related to mitochondrial regulation.

Methods
The bioactive components in GYPs and the potential targets in treating HF were obtained and screened using the network pharmacology approach, followed by drug-disease target prediction and enrichment analyses. The pharmacological effects of GYPs in cardioprotection, mitochondrial function, mitochondrial quality control, and underlying mechanisms were further investigated in Doxorubicin (Dox)-stimulated H9c2 cardiomyocytes.

Results
A total of 88 bioactive compounds of GYPs and their respective 71 drug-disease targets were identified. The hub targets covered MAPK, EGFR, PI3KCA, and Mcl-1. Enrichment analysis revealed that the pathways primarily contained PI3K/Akt, MAPK, and FoxO signalings, as well as calcium regulation, protein phosphorylation, apoptosis, and mitophagy process. In Dox-stimulated H9c2 rat cardiomyocytes, pretreatment with GYPs increased cell viability, enhanced cellular ATP content, restored basal oxygen consumption rate (OCR), and improved mitochondrial membrane potential (MMP). Furthermore, GYPs improved PINK1/parkin-mediated mitophagy without influencing mitochondrial fission/fusion proteins and the autophagic LC3 levels. Mechanistically, the phosphorylation of PI3K, Akt, GSK-3β, and the protein level of Mcl-1 was upregulated by GYP treatment.

Conclusion
Our findings reveal that GYPs exert cardioprotective effects by rescuing the defective mitophagy, and PI3K/Akt/GSK-3β/Mcl-1 signaling is potentially involved in this process.
Effect of Different Levels of Cinder and Vermicompost on Germination and Seedling Growth of Papaya (Carica papaya c.v Red Lady) its Treatment with GA3
Authors: Rai Rishika , Topno Samir E. , Bahadur Vijay 
Published: June 2024

An experiment was conducted to find out suitable growth hormone and growing medium for germination and seedling growth of papaya. The treatments included soaking the seed of papaya variety Red lady in GA3(200ppm) for 24.00 hours except for control. The perforated polythene bags of 4 x 5 cm size (150 gauges thickness) were used for sowing. The bags were filled with a mixture of Soil, Vermicompost, Cinder and Cocopeat in the ratio of 1:1:1, 1:2:1, 1:1:2 and 2:1:1. Experiment was laid out in Completely randomized design nine treatment with three replication. Findings indicate that treatment T9 Soil +Cocopeat +Vermicompost +Cinder (1:1:1:1) +GA3 200ppm performed best in terms of growth parameters viz., germination (77.37), days taken for completion of germination (15.27), seedling height (25.00 cm), number of leaves per seedling (13.53 cm), diameter of seedling (cm) (1.03), Leaf area (cm2) (97.64cm), Chlorophyll content (SPAD Value) (54.97), Length of longest tap root (4.52 cm) and Survival (%) (83.27) under Prayagraj agro-climatic condition.
Effect of Organic, Inorganic and Biofertilizer on Growth, Yield and Quality of Bottle Gourd (Lagenaria siceraria Mol.)
Authors: Tomar Vinit , Topno Samir E. , Bahadur Vijay , Kerketta Anita 
Published: June 2024

The present investigation was carried out at Research Farm, Department of Horticulture, Naini Agricultural Institute, SHUATS, Naini, Prayagraj, Uttar Pradesh during the Kharif- 2023 with a view to identify the effects of different combinations of organic and inorganic fertilizers and its role in growth, yield and quality of bottle gourd variety Sharada. The experiment was laid in Randomized block design with 13 treatments and 3 replications with different combination in RDF and application of organic manures and bio fertilizers. In this experiment we found that the treatment T9 (50% RDF + 50% Vermicompost + Azospirillum @ 1 Kg ha-1) was found to be best in the terms of growth parameters viz., vine length observed at 60 DAS (166.65 cm), number of branches per plant (5.63 branches), yield parameters like number of fruits per plant (17.41 fruits), fruit length (40.11 cm), fruit diameter (7.51 cm) and fruit weight (916.97 grams) along with better yield (79.84 q/ha) and quality TSS and Vitamin C content of bottle gourd. The highest net return was found in the T9 (50% RDF + 50% Vermicompost + Azospirillum @ 1 Kg ha-1) with Rs 1,81,473/ha) and the highest B:C ratio was found in the same with 2.32.
Deictic Expressions in the First SONAs of Rodrigo Duterte and Ferdinand Marcos Jr.
Authors: Pintado Ma. Sophia , Cereño Mark Jayce , Librea Annalie , Bejasa Rechie , Minoza Joemar Turno 
Published: June 2024

This study assumes that former President Rodrigo Duterte and President Ferdinand Marcos Jr. used different types of deixis in their first State of the Nation Address (SONAs). Supporting this assumption is the theory of Deictic Expressions by Stephen Levinson. This study is descriptive qualitative. Findings revealed that former President Duterte and President Marcos Jr. used different types of deixis in their speeches. The most dominant type of deixis used by former President Duterte is personal deixis, which obtained the highest frequency, particularly the pronoun "I". In contrast, the most prevalent deixis used by President Marcos is "personal deixis", particularly the pronoun "we". It is concluded that personal deixis was the most dominant type of deixis among the five types used by the two speakers in their speeches. Future researchers are encouraged to conduct a future study that will focus on the usage of deixis in books or speeches.
Child physical abuse and adult mental health: A national study
Authors: Sugaya Luisa , Hasin Deborah S. , Olfson Mark , Lin Keng‐Han , Grant Bridget F. , Blanco Carlos 
Published: July 2012

AbstractThis study characterizes adults who report being physically abused during childhood, and examines associations of reported type and frequency of abuse with adult mental health. Data were derived from the 2000–2001 and 2004–2005 National Epidemiologic Survey on Alcohol and Related Conditions, a large cross‐sectional survey of a representative sample (N = 43,093) of the U.S. population. Weighted means, frequencies, and odds ratios of sociodemographic correlates and prevalence of psychiatric disorders were computed. Logistic regression models were used to examine the strength of associations between child physical abuse and adult psychiatric disorders adjusted for sociodemographic characteristics, other childhood adversities, and comorbid psychiatric disorders. Child physical abuse was reported by 8% of the sample and was frequently accompanied by other childhood adversities. Child physical abuse was associated with significantly increased adjusted odds ratios (AORs) of a broad range of DSM‐IV psychiatric disorders (AOR = 1.16–2.28), especially attention‐deficit hyperactivity disorder, posttraumatic stress disorder, and bipolar disorder. A dose‐response relationship was observed between frequency of abuse and several adult psychiatric disorder groups; higher frequencies of assault were significantly associated with increasing adjusted odds. The long‐lasting deleterious effects of child physical abuse underscore the urgency of developing public health policies aimed at early recognition and prevention.
Synthesis of Ester Based Cationic Pyridinium Gemini Surfactants and Appraisal of Their Surface Active Properties
Authors: Patial Pankaj , Shaheen Arifa , Ahmad Ishtiaque 
Published: July 2012

AbstractNew pyridinium gemini surfactants have been synthesized by esterification of halogenated carboxylic acids with long chain fatty alcohols furnishing respective esters (dodecyl‐2‐chloroacetate, tetradecyl‐2‐chloroacetate, hexadecyl‐2‐chloroacetate, dodecyl‐2‐bromoacetate, tetradecyl‐2‐bromoacetate and hexadecyl‐2‐bromoacetate) followed by their subsequent treatment with 4,4′‐trimethylene dipyridine resulting in the formation of title Gemini surfactants: 4,4′‐(propane‐1,3‐diyl)bis1‐{2‐(dodecyloxy)‐2‐oxoethyl}; 4,4′‐(propane‐1,3‐diyl)bis{1‐(2‐(tetradecyloxy)‐2‐oxoethyl}; 4,4′‐(propane‐1,3‐diyl)bis{1‐(2‐(hexadecyloxy)‐2‐oxoethyl} dipyridinium chlorides; 4,4′‐(propane‐1,3‐diyl)bis{1‐(2‐(dodecyloxy)‐2‐oxoethyl}; 4,4′‐(propane‐1,3‐diyl)bis{1‐(2‐(tetradecyloxy)‐2‐oxoethyl} and 4,4′‐(propane‐1,3‐diyl)bis{1‐(2‐(hexadecyloxy)‐2‐oxoethyl} dipyridinium bromides. Their identifications are based on IR, 1H‐NMR, 13C‐NMR, DEPT, COSY and Mass spectral studies. Their surface active properties were also evaluated on the basis of surface tension and conductivity measurements.
PROGRESSIVISM AND THE DOCTRINE OF NATURAL RIGHTS
Authors: Ceaser James W. 
Published: July 2012

AbstractThis essay treats the Progressives' critique of the Founders' doctrine of natural rights. Natural rights had been attacked before the Progressive era—by proponents of the racial science of ethnology, advocates of philosophy of history, and followers of Charles Darwin—but the Progressives launched the most thoroughgoing and systematic critique in American history. The leading thinker conducting the critique was America's foremost philosopher John Dewey. His critique had five major points: (1) that America had entered an entirely new age of social and economic organization requiring a different political theory; (2) that all theoretical claims of truth, like natural rights, are relative to the age in which they were born and thrived; (3) that theoretical ideas serve the aims of different classes, with natural rights representing the economic and political interests of the emerging bourgeoisie; (4) that natural rights encouraged a diminished goal for human beings, emphasizing the fulfillment of individual self-interest rather a higher idea of human development and of social cooperation; and (5) that any metaphysical claim in politics is undemocratic by virtue of ascribing a standard of right that is prior to and higher than a decision of a democratic majority. The paper concludes by briefly sketching the influence that this critique had on the heirs of the Progressives, the modern liberals.
Correlates of Potentially Inappropriate Prescriptions of Benzodiazepines among Older Adults: Results from the ESA Study
Authors: Préville Michel , Bossé Cindy , Vasiliadis Helen-Maria , Voyer Philippe , Laurier Claudine , Berbiche Djamal , Pérodeau Guiilhème , Grenier Sébastien , Béland Sarah-Gabrielle , Dionne Pierre-Alexandre , Gentil Lia , Moride Yola 
Published: July 2012

RÉSUMÉLes données de l’étude ESA ont été appariées aux données d’utilisation des services médicaux et pharmaceutiques de la Régie d’assurance maladie du Québec pour documenter la prescription potentiellement non appropriée de benzodiazépines chez les personnes âgées. Nos résultats indiquent que 32% des répondants ont pris une dose journalière moyenne de 6.1 mg de l’équivalent diazépam pour une durée moyenne de 205 jours par année. Nos résultats indiquent aussi que presque la moitié, 48% des utilisateurs de benzodiazépines, ont reçu au moins une prescription de benzodiazépine potentiellement non appropriée pendant les 12 mois qui précédaient l’étude. Près de 23% des consommateurs ont reçu au moins une prescription concomitante de Bzs et d’un autre médicament pouvant résulter en une interaction sérieuse. De plus, les personnes âgées de 75 ans et plus avaient plus de chances de recevoir une Bz pour une longue période de temps que les personnes âgées de 65-74 ans. Cette étude a montré que la durée d’utilisation des benzodiazépines augmentait avec le nombre de prescripteurs et avec le nombre de pharmacies consultées pendant l’année. Le nombre de pharmacies utilisées a aussi été associé avec la présence d’une ordonnance non appropriée de benzodiazépines pendant la même année. Nos résultats plaident en faveur d’un système de santé plus intégré, incluant une révision régulière des médicaments pris par les personnes âgées.
Force of infection of dengue serotypes in a population-based study in the northeast of Brazil
Authors: CASTANHA P. M. S. , CORDEIRO M. T. , MARTELLI C. M. T. , SOUZA W. V. , MARQUES E. T. A. , BRAGA C. 
Published: July 2012

SUMMARYThis study investigated anti-dengue serotype-specific neutralizing antibodies in a random sample of dengue IgG-positive individuals identified in a survey performed in a hyperendemic setting in northeastern Brazil in 2005. Of 323 individuals, 174 (53·8%) had antibodies to dengue virus serotype 1 (DENV-1), 104 (32·2%) to DENV-2 and 301 (93·2%) to DENV-3. Monotypic infections by DENV-3 were the most frequent infection (35·6%). Of 109 individuals aged <15 years, 61·5% presented multitypic infections. The force of infection estimated by a catalytic model was 0·9%, 0·4% and 2·5% person-years for DENV-1, DENV-2 and DENV-3, respectively. By the age of 5 years, about 70%, 30% and 40% of participants were immune to DENV-3, DENV-2 and DENV-1, respectively. The data suggest that infection with DENV-1, -2 and -3 is intense at early ages, demonstrating the need for research efforts to investigate dengue infection in representative population samples of Brazilian children during early infancy.
Pneumonia in US hospitalized patients with influenza-like illness: BioSense, 2007–2010
Authors: BENOIT S. R. , BURKOM H. , McINTYRE A. F. , KNISS K. , BRAMMER L. , FINELLI L. , JAIN S. 
Published: July 2012

SUMMARYWe used data from BioSense, a national electronic surveillance system, to describe pneumonia in hospitalized patients with influenza-like illness (ILI). Ninety-five hospitals from 20 states reported ICD-9-CM-coded inpatient final diagnosis data during the study period of September 2007 to February 2010. We compared the characteristics of persons with and without pneumonia among those with ILI-related hospitalizations. BioSense captured 26 987 ILI-related inpatient hospitalizations; 8979 (33%) had a diagnosis of pneumonia. Analysis of trends showed highest counts of pneumonia during the 2007–2008 season and the second 2009 pandemic wave. Pneumonia was more common with increasing age. Microbiology and pharmacy data were available for a subset of patients; 107 (5%) with pneumonia had a bloodstream infection and 17% of patients were prescribed antiviral treatment. Our findings demonstrate the potential utility of electronic healthcare data to track trends in ILI and pneumonia, identify risk factors for disease, identify bacteraemia in patients with pneumonia, and monitor antiviral use.