bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cancer-Related Health and Educational Needs and Faith-Based Health Beliefs in an Urban Muslim Population
Authors: Choudhri Aisha , Adams-Campbell Lucile , Bright Mireille , Zhu Jialing , Dash Chiranjeev 
Published: April 2024

AbstractCancer screening behaviors in Muslims are under-researched, and there is limited data on how it relates to their unique cultural and religious beliefs. We assessed cancer prevention and screening-related health needs in the Washington DC area. We developed the needs assessment questionnaires and recruitment strategy in collaboration with key faith leaders from four mosques in our catchment area. A total of 203 participants were recruited through community outreach and engagement approaches and were included in the discussion when developing the needs assessment to ensure questions were religiously and culturally sensitive. Of the 203 participants, 56% of women reported receiving screening for a mammogram, while 83% of women reported receiving a screening for cervical cancer. Among men, 45% reported receiving a prostate cancer antigen test to screen for prostate cancer. Among both men and women, 35% reported ever receiving a screening for colorectal cancer. Women reported relying more on their faith when dealing with health concerns than men. Those who did not get screened for breast, colorectal, and cervical cancer relied more on their faith than those who did get screened for these cancers. Participants expressed interest in having health initiatives around cancer education, screening, and survivorship inside mosques. Faith beliefs can influence cancer screening behaviors; however, the relationship between these two variables needs further examination. Continued engagement with key faith leaders can help in leveraging religious beliefs to promote health education and cancer screening.
Effect of equilibrium contact angle on water equilibrium film thickness for the carbon dioxide–brine–mineral system based on surface force theory
Authors: Amadu Mumuni , Miadonye Adango 
Published: April 2024

AbstractThe thickness of the thin wetting film depends on disjoining pressure forces, and it evolves with pH evolution due to brine acidification at the physical and chemical conditions of geological carbon dioxide storage becoming thinner in response to dewetting. In the literature, molecular dynamic simulation (MDS) studies have been employed to understand the effect of pressure/capillary pressure on the thin wetting film evolution. In this paper, a theoretical approach based on the Frumkin–Derjaguin Equation (FDE), models of electric double layer repulsion, and van der Waals forces have been used for the calculation of the wetting film thickness. The approach excluded hydration forces contribution to disjoining pressure forces due partly to its poorly understood nature, and partly to the high salinity conditions encountered in geological carbon storage. Due to its promising global storage capacity compared to other lithologies, the carbon dioxide–brine–silica systems was chosen to simulate sandstone saline aquifers. The validation of the model benefited much from literature resources on data and a universal model of carbon dioxide–brine interfacial tension. Calculated results confirm pH-induced dewetting and they follow trends controlled by pH and pressure as found in the literature. The novelty of the paper can be seen from the fact that it has demonstrated a theoretical supplement to MDS studies in addition to justifying the fundamental utility and versatility of the FDE. Moreover, the paper links for the first time, a transcendental equation to the thin wetting film theory encountered in the carbon dioxide–solid–brine system found in geological carbon storage.
Scientific data and background behind the first detection of Meloidogyne enterolobii in Australia
Authors: Bond Samantha J. , Huston Daniel C. , Patel Shreya , Hodda Mike , Yadav Sonu , Bellgard Stanley E. 
Published: April 2024

AbstractThe parasitic guava root-knot nematode, Meloidogyne enterolobii Yang and Eisenback (syn. M. mayaguensis), has a wide distribution, host range and is established majorly in tropical-subtropical climates. A routine diagnostic analysis of symptomatic plant roots confirmed the first detection of M. enterolobii in Australia, near Darwin, Northern Territory. The morphology of female perineal patterns, second stage juveniles (J2s) and males were consistent with other reports of this species. The presence of M. enterolobii was first evaluated with a species-specific sequence-characterized amplified region (SCAR) and the intergenic spacer region (IGS2), followed by sequencing of the mitochondrial cytochrome c oxidase I and II (COI & COII) and large subunit ribosomal RNA (28S rRNA) gene regions. The nematode was detected on several important crop-host plants in Australia’s Northern Territory including chilli, tomato, capsicum, cucumber, pumpkin, eggplant, snake bean and sweet potato. The ability of M. enterolobii to colonise a variety of weeds and native Australian plants makes management challenging. The route of introduction of M. enterolobii is presently unknown but is under investigation.
Sustainability assessment of orange peel waste valorization pathways from juice industries
Authors: Manakas Pantelis , Balafoutis Athanasios T. , Kottaridi Constantina , Vlysidis Anestis 
Published: April 2024

Abstract
A wide variety of products such as high value-added bioactive materials, biofuels, biochemicals and bioplastics can be obtained by the valorization of waste streams in a comprehensive and holistic biorefinery concept. In this study a meta-analysis of the available technologies utilizing organic waste derived from the juice industry is conducted. Initially, a mass flow analysis is performed to quantitatively illustrate the available orange peel waste volumes in the EU followed by a geographic distribution. The overall sustainability of the available valorization scenarios is then analyzed by considering critical environmental, economic and energy indicators and comparing innovative and conventional valorization technologies. Innovative technologies are better in terms of energy requirements and extraction time and also, in product yield and environmental performance than the conventional ones (85.1%, 9.5% and 47.9% lower CO2 eq values for the extraction of essential oils, pectin and phenolic compounds respectively). In terms of orange peel waste valorization scenarios, landfilling shares the largest environmental impact, followed by thermochemical and biological conversion alternatives. Complex biorefinery schemes are proportionate to environmental performance and energy consumption, but inversely proportionate to production cost. Finally, a trade-off analysis illustrates a positive correlation between environmental indicators of the most under study valorization scenarios.
Case study analysis of innovative producers toward sustainable integrated crop-livestock systems: trajectory, achievements, and thought process
Authors: Moojen Fernanda Gomes , Ryschawy Julie , Wulfhorst J. D. , Archer David W. , de Faccio Carvalho Paulo César , Hendrickson John R. 
Published: April 2024

AbstractIntegrated crop-livestock systems (ICLS) are more complex to properly manage than specialized farming systems due to multiple interactions between crops, livestock, and grassland. Despite individual and structural barriers to adopting sustainable ICLS, some innovative producers have successfully conducted integrated production practices. In this context, a research gap exists in understanding the motivations and incentives for transitioning to such systems. This study aims to address ICLS adoption barriers by analyzing the trajectory, achievements, and thought processes of 15 producers practicing ICLS. Our objectives were to (1) highlight producers’ perceptions of ICLS levers and barriers and (2) identify turning point factors that enabled producers to overcome the barriers. We used a unique set of cases in three continental regions (southern Brazil, the northern Great Plains region in the United States, and southern France) and conducted semi-structured interviews. Interviewees emphasized that ICLS imply dealing with barriers ranging from mindset change to operational adaptations, but they also emphasized the rewarding nature of ICLS when properly managed. All their trajectories had important turning points, such as programs or initiatives, human influence, and broader social and economic reasons that resulted in shifts in their production practices and thought processes. The cases also highlighted that integrating crops and livestock positively impacted family producers’ business outcomes, soil health, and livelihood options. Still, individual barriers, including operational management, and structural barriers, including stakeholder awareness and commitment, must be overcome. Encouraging initiatives that offer a systemic approach and promote knowledge exchange can address part of ICLS adoption barriers. Initiatives must embrace a broader innovation ecosystem, having extension teams in close contact with researchers and stakeholders to assist producers in providing support for a more sophisticated level of management that ICLS require. Overall, we found commonalities in consciousness and proactiveness in remarkable cases that could inspire broader sustainability transitions.
Temperature-Controlled Laser Processing of Shape Memory Wires: Spherical Ends as Connectors for System Integration
Authors: Schuleit Marvin , Kutlu Yunus , Maaß Burkhard , Stötzel Nicole , Frenzel Jan , Esen Cemal , Eggeler Gunther , Ostendorf Andreas 
Published: April 2024

AbstractNickel–Titanium-based shape memory alloys have reached a high technological relevance in the medical field and also for actuation/energy conversion. At present, the interest in new actuation solutions is steadily increasing. However, one important challenge for the design of new actuators is the lack of connection and coupling options, which often hinders a reliable system integration. To address this challenge, this study presents a temperature-controlled laser processing approach for the generation of spherical ends on shape memory wires, which allow a relatively simple integration into different types of systems (e.g., printed circuit boards) in a form-fitting manner. For this purpose, an experimental setup with an integrated pyrometer was used to establish spherical ends on thin NiTi wires with a diameter of 0.24 mm. The resulting microstructures and the functional properties were investigated using scanning electron microscopy, thermal analysis, uniaxial tensile testing, actuation fatigue testing, and hardness measurements. The results obtained in the present study indicate that our laser procedure successfully yields reliable connection options for NiTi wires, without harming the functional performance of the material.
Research on cooperative control method of comprehensive pressure relief and anchor grouting reinforcement in deep mining roadways
Authors: Jiang Zhenhua , Jiang Bei , Zhang Chong , Ma Yukun , Wang Yetai , Li Donghao , Wang Shuai 
Published: April 2024

AbstractTo address the surrounding rock control problems in high-stressed deep mining roadways, we used Suncun Coal Mine with maximum mining depth in China as the engineering background to analyze failure laws of surrounding rock of gob-side entry driving. Combined with field tests of anchor grouting parameters, we carried out numerical simulation with multi factors. The evolution of surrounding rock stress and displacement under different pressure relief parameters were clarified. On the basis, we proposed an integrated control method for the comprehensive pressure relief for coal and rock mass and anchor grouting reinforcement in deep mining roadway. We used geomechanical model test to compare gob-side entry driving method and this new method. The results showed that this new method can reduce average stress at the working face by 15.8% and peak stress of roadway shoulder by 12.5%. We applied this method in the field, which reduced roadway deformation by 535 mm.
Evolution of mining-induced water inrush disaster from a hidden fault in coal seam floor based on a coupled stress–seepage–damage model
Authors: Shao Jianli , Zhang Qi , Zhang Wenquan 
Published: April 2024

AbstractWater inrush originating from hidden faults in the coal seam floor is challenging to prevent due to their concealed nature. This paper develops a coupled stress–seepage–damage model for simulating rock fracture, implemented using the finite element method. The model is validated against compression-seepage tests on rock samples, capturing realistic dynamics of shear and tensile damage as well as permeability. The model is applied to the 27305 working face of a coal mine in Shandong Province, China, revealing the evolution of water inrush caused by a hidden fault. The results indicate that as the working face progresses, both the floor damage and the internal damage within the hidden fault escalate gradually. When mining reaches 80 m, the hidden fault has been activated internally, and the depth of floor damage reaches 13 m, which still has a certain distance from the hidden fault. At 100 m, the depth of the floor damage has stabilized, while the stress concentration at the hidden fault's tip increases, and it begins to expand if conditions for tensile damage are met. By the time mining reaches 110 m, the hidden fault has expanded 9.2 m in length and connected with the floor damage zone, forming a water inrush channel that links the aquifer to the working face, presenting a significant water inrush risk. This work provides an intuitive approach to understanding the evolution of water inrush from a hidden fault, aiding in the prevention of water inrush disasters in practical engineering applications.
Mustafa Hamid: al-Qaidas „wichtigster Historiker“ oder verzerrender Propagandist und Ideologe?
Authors: Häußermann Nikolai 
Published: April 2024

ZusammenfassungIn vorliegenden Artikel wird die Zuverlässigkeit eines „afghanischen Arabers“ namens Mustafa Hamid als historische Quelle untersucht. Hamids Texte bieten einen einzigartigen Einblick in die Entwicklung al-Qaidas, die Ursprünge der Taliban-Bewegung und die ersten Anfänge des Islamischen Staates. Diese Schilderungen sind besonders interessant, weil Hamid die entscheidenden Protagonisten persönlich kannte, die Entwicklungen der sogenannten „afghanischen Araber“ an der afghanisch-pakistanischen Grenze in den 1980er und 1990er Jahren hautnah miterlebte und zum Teil selbst mitgestaltete. Diese Vorteile werfen aber auch ein Problem auf: Inwieweit konnte Hamid aufgrund seiner persönlichen Einbindung in die Ereignisse, Prozesse und Organisationen vertraut werden?
AttSiOff: a self-attention-based approach on siRNA design with inhibition and off-target effect prediction
Authors: Liu Bin , Yuan Ye , Pan Xiaoyong , Shen Hong-Bin , Jin Cheng 
Published: April 2024

AbstractSmall interfering RNA (siRNA) is often used for function study and expression regulation of specific genes, as well as the development of small molecule drugs. Selecting siRNAs with high inhibition and low off-target effects from massive candidates is always a great challenge. Increasing experimentally-validated samples can prompt the development of machine-learning-based algorithms, including Support Vector Machine (SVM), Convolutional Neural Network (CNN), and Graph Neural Network (GNN). However, these methods still suffer from limited accuracy and poor generalization in designing potent and specific siRNAs.In this study, we propose a novel approach for siRNA inhibition and off-target effect prediction, named AttSiOff. It combines a self-attention-based siRNA inhibition predictor with an mRNA searching package and an off-target filter. The predictor gives the inhibition score via analyzing the embedding of siRNA and local mRNA sequences, generated from the pre-trained RNA-FM model, as well as other meaningful prior-knowledge-based features. Self-attention mechanism can detect potentially decisive features, which may determine the inhibition of siRNA. It captures global and local dependencies more efficiently than normal convolutions. The tenfold cross-validation results indicate that our model outperforms all existing methods, achieving PCC of 0.81, SPCC of 0.84, and AUC of 0.886. It also reaches better performance of generalization and robustness on cross-dataset validation. In addition, the mRNA searching package could find all mature mRNAs for a given gene name from the GENOMES database, and the off-target filter can calculate the amount of unwanted off-target binding sites, which affects the specificity of siRNA. Experiments on five mature siRNA drugs, as well as a new target gene (AGT), show that AttSioff has excellent convenience and operability in practical applications.
Graphical Abstract
A multimodal approach to polysemy: the senses of touch
Authors: Bolumar Martínez Irene , Alcaraz Carrión Daniel , Valenzuela Manzanares Javier 
Published: April 2024

AbstractThis study investigated whether speakers use multimodal information (speech and gesture) to differentiate the physical and emotional meanings of the polysemous verb touch. We analyzed 302 hand gestures that co-occurred with this perception verb. For each case, we annotated (1) the meaning of touch (physical vs. emotional), (2) the gesture referent speakers physically touched (other-touch vs. self-touch), (3) the personal pronoun following the verb and (4) if they used intensifiers and negation. There were three main findings. First, we have seen that when speakers express the physical meaning, they are likely to reach an external referent (other-touch), but when they imply the emotional meaning, they tend to touch their own body (self-touch). Second, the most frequent co-speech gesture (chest-touching gesture) was associated with the emotional meaning, uncovering the metaphor the heart is container for emotions. Third, this study showed that the physical meaning of touch usually coexists with a wide variety of personal pronouns and negation words; in contrast, the emotional meaning of touch occurs primarily with the pronoun me and it is usually modified by intensifiers. Thus, speakers use both speech and gesture to differentiate the meanings of the polysemous verb touch.
Midfrontal conflict theta and parietal P300 are linked to a latent factor of DSM externalising disorders
Authors: Neo Phoebe S.-H. , McNaughton Neil , Sellbom Martin 
Published: April 2024

Abstract
Psychiatric illnesses form spectra rather than categories, with symptoms varying continuously across individuals, i.e., there is no clear break between health and disorder. Dimensional measures of behaviour and brain activity are promising targets for studying biological mechanisms that are common across disorders. Here, we assessed the extent to which neural measures of the sensitivity of the three biological systems in the reinforcement sensitivity theory (RST) could account for individual differences in a latent general factor estimated from symptom counts across externalising disorders (EXTs). RST explanatory power was pitted against reduced P300, a reliable indicator of externalising per previous research. We assessed 206 participants for DSM-5 EXTs (antisocial personality disorder, conduct disorder, attention-deficit/hyperactivity disorder, intermittent explosive disorder symptoms, alcohol use disorder, and cannabis use disorder). Of the final sample, 49% met diagnostic criteria for at least one of the EXTs. Electroencephalographic measures of the sensitivities of the behavioural activation system (BAS), the fight/flight/freeze system, and the behavioural inhibition system (BIS), as well as P300 were extracted from the gold bar-lemon and stop-signal tasks. As predicted, we found that low neural BIS sensitivity and low P300 were uniquely and negatively associated with our latent factor of externalising. Contrary to prediction, neural BAS/“dopamine” sensitivity was not associated with externalising. Our results provide empirical support for low BIS sensitivity and P300 as neural mechanisms common to disorders within the externalising spectrum; but, given the low N involved, future studies should seek to assess the replicability of our findings and, in particular, the differential involvement of the three RST systems.
The indications, surgical techniques, and complications of transoral robotic surgery in total laryngectomy: a systematic review
Authors: Poutoglidis Alexandros , Forozidou Evropi , Fyrmpas Georgios , Vlachtsis Konstantinos , Karamitsou Paraskevi 
Published: April 2024

AbstractObjectiveTransoral robotic surgery total laryngectomy is a promising procedure. We conducted a systematic review to study the indications, surgical techniques and complications of this procedure.MethodsWe followed the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement.ResultsWe concluded with 5 studies and 27 surgeries. The main indications of transoral robotic surgery total laryngectomy were selected recurrent laryngeal squamous cell carcinomas, dysfunctional larynx, and specific primary non-squamous cell carcinoma laryngeal cancers. The rate of pharyngocutaneous fistula was 20 per cent overall. In every reported cancer case, the specimen was excised within negative surgical margins. The average time of the procedure was 282.6 minutes.ConclusionTransoral robotic surgery total laryngectomy is a safe procedure of high value. The preservation of strap muscles and hyoid bone as well as the sacrifice of less mucosa compared to the traditional technique reduces the risk of certain complications and improves the swallowing outcome.
Incidence and distribution of contralateral lymph node metastasis associated with human papillomavirus-related oropharyngeal squamous cell carcinoma
Authors: Kornfeld Belen , Kyang Lee , Taha Ahmed , McCloy Rachael , Chin Vanessa , Leavers Brett , Floros Peter , Earls Peter , Forstner Dion , Addison Alfred , Crawford Julia , Gallagher Richard 
Published: April 2024

AbstractObjectiveTo analyse the rate of contralateral nodal metastasis in human papillomavirus (HPV)-associated oropharyngeal carcinoma and identify the patient cohorts that would benefit from bilateral neck treatment.MethodsA retrospective cohort review was performed on 110 HPV-positive oropharyngeal carcinoma patients who underwent transoral robotic surgery and bilateral neck dissections from 2012 to 2022. The primary outcome was to investigate the pathological incidence and location of contralateral neck node metastasis.ResultsThe contralateral nodal disease rate was 12.7 per cent (n = 14), of which 2 patients (2 per cent) were occult findings, with comparable results between tongue base and tonsil sub-groups. The most commonly involved contralateral nodal station was level II (11 of 110 patients, 10 per cent). The presence of extra-nodal extension and multiple ipsilateral positive nodes was associated with increased risk of contralateral nodal disease.ConclusionThe incidence of contralateral nodal and occult disease in the studied cohort is low. The characteristics of patients who may benefit from bilateral neck treatment were demonstrated.