bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sociotechnical imaginaries in academic medicine strategic planning: a document analysis
Authors: Rowland Paula , Brydges Madison , Kulasegaram Kulamakan 
Published: May 2024

AbstractPurpose Along with other industries, healthcare is becoming increasingly digitized. Our study explores how the field of academic medicine is preparing for this digital future. Method Active strategic plans available in English were collected from faculties of medicine in Canada (n = 14), departments in medical schools (n = 17), academic health science centres (n = 23) and associated research institutes (n = 5). In total, 59 strategic plans were subjected to a practice-oriented form of document analysis, informed by the concept of sociotechnical imaginaries. Results On the one hand, digital health is discursively treated as a continuation of the academic medicine vision, with expansions of physician competencies and of research institutes contributions. These imaginaries do not necessarily disrupt the field of academic medicine as currently configured. On the other hand, there is a vision of digital health pursuing a robust sociotechnical future with transformative implications for how care is conducted, what forms of knowledge are prioritized, how patients and patienthood will be understood, and how data work will be distributed. This imaginary may destabilize existing distributions of knowledge and power. Conclusions Looking through the lens of sociotechnical imaginaries, this study illuminates strategic plans as framing desirable futures, directing attention towards specific ways of understanding problems of healthcare, and mobilizing the resources to knit together social and technical systems in ways that bring these visions to fruition. There are bound to be tensions as these sociotechnical imaginaries are translated into material realities. Many of those tensions and their attempted resolutions will have direct implications for the expectations of health professional graduates, the nature of clinical learning environments, and future relationships with patients. Sociology of digital health and science and technology studies can provide useful insights to guide leaders in academic medicine shaping these digital futures.
Advancing collaboration in health professions education in the general practice domain, developing a national research agenda
Authors: de Groot Esther , der Vossen Marianne Mak-van , Slootweg Irene , Çorum Meryem , Kramer Anneke , Muris Jean , Scherpbier Nynke , Thoonen Bart , Damoiseaux Roger 
Published: May 2024

Abstract
Background
Health professions education (HPE) research in the General Practice domain (GP-HPE) is vital for high-quality healthcare. Collaboration among GP-HPE researchers is crucial but challenging. Formulating a research agenda, involving stakeholders, and fostering inter-institutional collaboration can address these challenges and connect educational research and practice.

Methods
We used Q-methodology to explore perspectives on GP-HPE research of participants from all Dutch postgraduate GP training institutes. Participants individually sorted statements based on the relevance of future GP-HPE research for educational practice. Data analysis comprised inverted factor analysis, rotation, and qualitative interpretation of configurations of all statements. The National Meeting on Educational Research took a participatory approach.

Results
We included 73 participants with diverse involvement in GP-HPE research. We identified five distinct perspectives, each representing a research focus area for developing and innovating GP education: the clinician scientist, the socially engaged GP, the specific GP identity, the GP as an entrepreneur, and the GP engaged in lifelong learning.

Discussion
The resulting five perspectives align with General Practice hallmarks. Q-methodology and a participatory approach facilitated collaboration among stakeholders. Successful inter-institutional collaboration requires a common goal, neutral leadership, participant commitment, regular meetings, audit trail support, process transparency, and reflexivity. Future research should address evidence gaps within these perspectives.

Conclusion
Using Q-methodology turned out to be valuable for compiling a national research agenda for GP-HPE research. The research process helped to cross boundaries between researchers in different institutions, thus putting inter-institutional collaborative advantage center stage. Our approach could provide a conceivable procedure for HPE researchers worldwide.
The Role of Parental Verbal Threat Information in Children’s Fear Acquisition: A Systematic Review and Meta-analysis
Authors: Nimphy Cosima Anna , Mitrou Vasiliki , Elzinga Bernet M. , Van der Does Willem , Aktar Evin 
Published: May 2024

AbstractChildren can acquire fears of novel stimuli as a result of listening to parental verbal threat information about these stimuli (i.e., instructional learning). While empirical studies have shown that learning via parental information occurs, the effect size of parental verbal threat information on child fear of a novel stimulus has not yet been measured in a meta-analysis. We conducted a systematic review and meta analysis to assess the effect of parents’ verbal statements on their children’s fear acquisition. Additionally, we explored potential moderators of this effect, namely, parent and child anxiety levels, as well as child age. WebOfScience, Pubmed, Medline, and PsycINFO were used to identify eligible studies that assessed children’s (30 months to 18 years old) fear of novel stimuli after being exposed to parental verbal threat information. We selected 17 studies for the meta-analysis and 18 for the systematic review. The meta-analysis revealed a significant causal effect of parental verbal threat information on children’s fear reaction towards novel stimuli [g = 1.26]. No evidence was found for a moderation of verbal learning effects, neither by child or parent anxiety levels nor by child age. The effect of parents’ verbal threat information on children’s fear of novel stimuli is large and not dependent on anxiety levels or child age.
Are corporate social responsibility and environmental management ‘influencers’ of performance in companies of the energetic sector?
Authors: Ruiz-López Jesús , Para-González Lorena , Mascaraque-Ramírez Carlos 
Published: May 2024

AbstractPrior research has suggested that Corporate Social Responsibility (CSR) may affect Environmental Management (EM). Nevertheless, there has been a lack of empirical studies that have examined these relationships, specially, in companies of the energetic field. This research empirically examines whether there is a positive relationship between the implementation of a CSR culture in a company and the obtaining of better Operational Performance, as well as between CSR and EM processes and also between EM and Operational Performance. The analysis of the results obtained through the Partial Least Squares (PLS) methodology concludes that there is a positive relationship between all of them, including this paper a main contribution to Literature as it is the fact that EM plays a mediator role increasing the CSR impact over Operational Performance. The major implication derived from this study is that investments in CSR and EM practices towards all the company stakeholders should positively affect performance. Therefore, both should be equally as important as other functions of a firm.
Nonlocality of three-qubit states of a nuclear spin-7/2
Authors: Furman Gregory , Sokolovsky Vladimir 
Published: May 2024

AbstractAdvances in quantum information processing can open a way for numerous applications of the processing in various fields of science and technology: communication, precision measurement, computing, nano-scale detectors, and sensors. Classical and various quantum correlations have been studied in real spin 1/2 systems. The nonlocality measures provide a novel classification scheme for bipartite states, highlighting that nonlocality is a quantum resource distinct from other types of quantum correlations. We first studied the temperature and field dependencies of nonlocality measure in the three fictitious spin 1/2 system, which represents a nuclear spin-7/2 placed in magnetic and inhomogeneous electric fields. The relationship between nonlocality and other quantum correlations (entanglement and geometric discord) was studied. The Hamiltonian and spin operators for a spin 7/2 are represented in the basis formed by the Kronecker products of the Pauli matrices. This transformation allows us to represent a spin 7/2 as a system of three coupled fictitious spins 1/2 and, from the quantum information point of view, as an equivalent system of three coupling qubits. Well-developed methods were used to calculate measures of quantum correlations. For example, we consider 59Co (spin 7/2) in the compounds [Co(NH3)5Cl]Cl2 and Ca3Co2O6. The interaction between the fictitious spins of 59Co nuclei depends on the magnitude and direction of the external magnetic field. Other potential cases of quantum correlations can be realized based on nuclear spins 7/2 in solid-state systems, for instance, such as 51V, 165Ho, or 123Sb.
Beneficial use of sediments, tools, pilot sites and measuring techniques developed and used within seven European Union INTERREG projects
Authors: Wijdeveld Arjan , Lemière Bruno , Coftier Aline , Laperche Valerie , Bataillard Philippe , Masson Eric , Lord Richard , Torrance Keith , Harrington Joe , Batel Brano , Wensveen Marco , Hamilton Alasdair , Debuigne Tristan 
Published: May 2024

Abstract
Purpose
The EU Water Framework Directive (European Union Off J Eur Comm 2000) and EU Waste Framework Directive (European Union Off J Euro Union 2008) impacted the Beneficial Use (BU) of sediments in Europe. INTERREG has supported initiatives to change the perception that sediments are a waste. In this paper we provide an overview of tools, pilot sites and measuring techniques developed and used for the BU of sediments within seven European Union INTERREG projects. We illustrate the lessons learned regarding barriers and enablers for BU of sediments.

Materials and methods
BU of sediments is a combination of factors. The following aspects are considered. The sediment must be suitable for use and be in engineering compliance. The sediment must also need to meet the end of waste criteria, as well as to be in environmental compliance. To check in the field if engineering and environmental compliance is feasible, on-site analyses and decision support tools are needed. When BU use is possible, there must be a benefit, either in an added socio-economic value or in ecosystem services. To define benefits the impact of Business as Usual (BAU) should also be expressed. Stakeholder perception and spatial restraints determine areas for BU of sediments with spatial consensus.

Results and discussion
The pilots and case studies described in this paper are examples of different applications of BU of sediments in northwest Europe. The tools, equipment, pilot tests and on-site monitoring techniques developed by the identified INTERREG projects are useful as BU enablers, for both citizens (an enabler is what is in it for me versus a barrier like residents opposing to proposed developments in their local area or the Not In My Back Yard (NIMBY) principle), and for regulators (what are the risks versus benefits as compared to BAU).

Conclusions
The main barriers for beneficial use of sediments are the social acceptance when sediments are used on land (often seen as waste disposal) and the extra direct cost versus the cost for disposal, while indirect benefits such as the potential for nature development, the impact on Gross Domestic Product (GDP) or more locally on the extra jobs created, are generally not considered. Also, the impact of BAU is often not explicitly considered.
Ethical Stakes for Past, Present, and Prospective Tuberculosis Isolate Research Towards a Multicultural Data Sovereignty Model for Isolate Samples in Research
Authors: Anderson A. , Meher M. , Maroof Z. , Malua S. , Tahapeehi C. , Littleton J. , Arcus V. , Wade J. , Park J. 
Published: May 2024

AbstractTuberculosis (TB) is a potentially fatal infectious disease that, in Aotearoa New Zealand (NZ), inequitably affects Asian, Pacific, Middle Eastern, Latin American, and African (MELAA), and Māori people. Medical research involving genome sequencing of TB samples enables more nuanced understanding of disease strains and their transmission. This could inform highly specific health interventions. However, the collection and management of TB isolate samples for research are currently informed by monocultural biomedical models often lacking key ethical considerations. Drawing on a qualitative kaupapa Māori–consistent study, this paper reports on preliminary discussions with groups of Māori, Pacific, and Afghan people in NZ, whose communities have been harmed by TB and TB stigma. Participants’ discussions highlight key concerns and meanings that ought to inform the development of guidelines and a more robust consultative process for the governance of how TB isolate samples are collected and used both retrospectively and in future research. We argue for ethical processes to be culturally nuanced and community-generated, flexible and meaningful, and situated in relation to the physical and symbolic effects of TB. We discuss the significance of Indigenous data sovereignty, rights, and kāwanatanga (governorship) in shaping a multicultural data sovereignty model.
Soziale und solidarische Ökonomie, ökosoziale Transformation und ihr potenzieller Beitrag für Gemeinwohl und Klimaschutz
Authors: Elsen Susanne 
Published: May 2024

ZusammenfassungIm Mittelpunkt dieses Beitrags steht die Frage, ob und wie soziale und solidarische Ökonomien (SSE) zur ökosozialen Transformation beitragen können. Es geht um Ansätze diversen Wirtschaftens (Gibson-Graham et al. 2013), welche gleichzeitig positive soziale und ökologische Effekte erzielen können. Nicht berücksichtigt wird die Bandbreite kulturell eingebetteter solidarischer Ökonomien, die den Lebensunterhalt großer Teile der Bevölkerung des globalen Südens decken (Acosta 2012) oder die solidarökonomische Selbsthilfe von Migrant:innen aus dem globalen Süden in Europa (Tadesse 2023). Diese Varianten und die zugrundeliegenden Epistemologien sollten jedoch als postkoloniale und postkapitalistische Alternativen (Kothari et al. 2019; Sarr 2022) zur Entwicklung westlicher Prägung angesichts der multiplen Krise und der dringenden ökologischen Erfordernisse erkannt und geschützt werden. Sie sind, wie auch Formen der SSE in Wohlfahrtstaaten, potenzielle Elemente eines ökosozialen Gesellschaftsmodells.
The roles of the kynurenine pathway in COVID-19 neuropathogenesis
Authors: Dehhaghi Mona , Heydari Mostafa , Panahi Hamed Kazemi Shariat , Lewin Sharon R. , Heng Benjamin , Brew Bruce J. , Guillemin Gilles J. 
Published: May 2024

AbstractThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly contagious respiratory disease Corona Virus Disease 2019 (COVID-19) that may lead to various neurological and psychological disorders that can be acute, lasting days to weeks or months and possibly longer. The latter is known as long-COVID or more recently post-acute sequelae of COVID (PASC). During acute COVID-19 infection, a strong inflammatory response, known as the cytokine storm, occurs in some patients. The levels of interferon‐γ (IFN‐γ), interferon-β (IFN-β), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α) are particularly increased. These cytokines are known to activate the enzyme indoleamine 2,3-dioxygenase 1 (IDO-1), catalysing the first step of tryptophan (Trp) catabolism through the kynurenine pathway (KP) leading to the production of several neurotoxic and immunosuppressive metabolites. There is already data showing elevation in KP metabolites both acutely and in PASC, especially regarding cognitive impairment. Thus, it is likely that KP involvement is significant in SARS-CoV-2 pathogenesis especially neurologically.
Effect of Cabergoline on weight and glucose metabolism in patients with acromegaly
Authors: Varaldo E. , Prencipe N. , Bona C. , Cuboni D. , Aversa L. S. , Sibilla M. , Bioletto F. , Berton A. M. , Gramaglia C. , Gasco V. , Ghigo E. , Grottoli S. 
Published: May 2024

Abstract
Purpose
Cabergoline (CAB) has shown to have benefic effects on the metabolism in different clinical settings but its metabolic role in acromegaly disease has not been studied yet. Aim of our study was to evaluate the impact of CAB on glucose metabolism and weight in patients with acromegaly.

Methods
All patients with acromegaly undergoing continuous treatment with CAB for at least 6 months were retrospectively screened. Exclusion criteria were discontinuation of CAB for more than one month, change of antidiabetic or other therapy for acromegaly, concomitant untreated hormonal deficiency, initiation of pregnancy and/or breastfeeding. All patients were evaluated in terms of biochemical disease control, glucose metabolism and weight at baseline (T0) and after the introduction of CAB therapy at 6 (T6) and 12 months (T12).

Results
Twenty-six patients (15 females and 11 males) were evaluated at T0 and T6 and 19 patients (12 females and 7 males) were also evaluated at T12. Insulin-like growth factor I (IGF-I) and prolactin (PRL) levels were significantly lower at T6 and T12 compared to baseline (p < 0.001 for IGF-I, p < 0.05 for PRL) even if no further differences were observed between T12 and T6. Considering the entire cohort, no differences were appreciated regarding the metabolic parameters but a significant reduction in weight and body mass index (BMI) was observed at both T6 (p = 0.009 for weight, p = 0.021 for BMI) and T12 (p = 0.014 for weight, p = 0.017 for BMI) compared to baseline.

Conclusion
Our results confirm the efficacy of CAB in providing a significant improvement in the biochemical disease control but do not demonstrate a marked benefit on glucose metabolism of acromegaly patients. In such patients, CAB appears to have a rapid effect on weight and BMI, with significant changes noticeable as early as 6 months and persisting for at least 12 months.
Multilayer quantile graph for multivariate time series analysis and dimensionality reduction
Authors: Silva Vanessa Freitas , Silva Maria Eduarda , Ribeiro Pedro , Silva Fernando 
Published: May 2024

AbstractIn recent years, there has been a surge in the prevalence of high- and multidimensional temporal data across various scientific disciplines. These datasets are characterized by their vast size and challenging potential for analysis. Such data typically exhibit serial and cross-dependency and possess high dimensionality, thereby introducing additional complexities to conventional time series analysis methods. To address these challenges, a recent and complementary approach has emerged, known as network-based analysis methods for multivariate time series. In univariate settings, quantile graphs have been employed to capture temporal transition properties and reduce data dimensionality by mapping observations to a smaller set of sample quantiles. To confront the increasingly prominent issue of high dimensionality, we propose an extension of quantile graphs into a multivariate variant, which we term “Multilayer Quantile Graphs”. In this innovative mapping, each time series is transformed into a quantile graph, and inter-layer connections are established to link contemporaneous quantiles of pairwise series. This enables the analysis of dynamic transitions across multiple dimensions. In this study, we demonstrate the effectiveness of this new mapping using synthetic and benchmark multivariate time series datasets. We delve into the resulting network’s topological structures, extract network features, and employ these features for original dataset analysis. Furthermore, we compare our results with a recent method from the literature. The resulting multilayer network offers a significant reduction in the dimensionality of the original data while capturing serial and cross-dimensional transitions. This approach facilitates the characterization and analysis of large multivariate time series datasets through network analysis techniques.
Associated factors of stress, urgency, and mixed urinary incontinence in a geriatric outpatient assessment of older women with hip fracture
Authors: Hellman-Bronstein Aino T. , Luukkaala Tiina H. , Ala-Nissilä Seija S. , Nuotio Maria S. 
Published: May 2024

Abstract
Purpose
Urinary incontinence (UI) is known to be common among older female hip fracture patients. Little is known about different subtypes of UI among these patients. Our aim was to identify factors associated with subtypes of UI in a cross-sectional design.

Methods
1,675 female patients aged ≥ 65 and treated for their first hip fracture in Seinäjoki Central Hospital, Finland, during 2007–2019, were included in a prospective cohort study. Of these, 1,106 underwent comprehensive geriatric assessment (CGA), including questions on continence, at our geriatric outpatient clinic 6 month post-fracture. A multivariable-adjusted multinomial logistic regression model was used to examine factors associated with UI subtypes.

Results
Of the 779 patients included, 360 (46%) were continent and 419 (54%) had UI 6-month post-fracture. Of the women with UI, 117 (28%) had stress UI, 183 (44%) had urgency UI and 119 (28%) had mixed UI, respectively. Mean age of the patients was 82 ± 6,91. In multivariable analysis, depressive mood and poor mobility and functional ability were independently associated with stress UI. Fecal incontinence (FI) and Body Mass Index (BMI) over 28 were independently associated with urgency UI. Mixed UI shared the aforementioned factors with stress and urgency UI and was independently associated with constipation.

Conclusions
Mixed UI was associated with most factors, of which depressive mood and impaired mobility and poor functional ability were shared with stress UI, and FI and higher BMI with urgency UI. CGA is key in assessing UI in older hip fracture patients, regardless of subtype.
Hybrid structured silk-rPET nanotechnical cloth for advanced air purification
Authors: Hossain Md. Tanvir , Shahid Md. Abdus 
Published: May 2024

AbstractAir pollution has become a significant global issue due to its detrimental environmental and human health effects. In this study, a novel approach was taken to address these challenges by developing a recycled polyethylene terephthalate (rPET) nano-coated silk technical cloth embedded with green-synthesized silver nanoparticles (AgNPs) using a solution electrospinning technique. The filtration performance of the developed material was assessed through particle filtration efficiency (PFE) tests, while differential pressure (DP) tests were conducted to evaluate pressure drop. SEM, FTIR, tensile, antibacterial, radiative heat barrier performance, and moisture management properties of the developed samples were also performed. Maximum 96.58% of filtration performance was observed with corresponding low differential pressures of 29.1 Pa/cm2; maximum tensile force and elongation% were 157.47 N and 15.32%, respectively of the developed samples. FTIR analysis confirmed the presence of silk, rPET, sodium alginate, and AgNPs in the developed sample. Antibacterial assays demonstrated inhibition against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Moisture management property revealed water penetration resistance and radiative heat barrier testing showed good barrier performance. These results make the promising potential of the developed material as an advanced air filter.
Graphical Abstract