bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frequency of Second Mesiobuccal Canal in Permanent Maxillary Molars: An Observational Study
Authors: Sheikh Md Abdul Hannan , Badsha Taib Bin , Howlader Md Mujibur Rahman , Rahman Mirza Md Arifur 
Published: April 2024

Background: The success of root canal therapy in endodontics is heavily dependent on identifying a second mesiobuccal canal (MB2) in permanent maxillary molars. A comprehensive understanding of internal anatomy, particularly the recognition of MB2, is crucial for the effective treatment of this commonly encountered tooth. This study aimed to investigate the prevalence and occurrence of the second mesiobuccal canal in permanent maxillary first and second molars.
Methods: This cross-sectional study that was conducted at the Department of Conservative Dentistry & Endodontics, Military Dental Centre Dhaka, Bangladesh from January 2018 to December 2018. The analysis involved a total of 200 maxillary first molars and 200 maxillary second molars. In the initial phase for both groups, teeth were examined with the naked eye followed by microscopic assessment. Data analysis was conducted with MS Office tools.
Results: In naked eye observation, the frequency of MB2 canals in the first molar teeth was found 64%, and in the second molar teeth it was found 56%. On the other hand, by microscopic assessment, the frequency of MB2 canals in the first molar teeth was found 96%, and in the second molar teeth, it was found 84%.
Conclusion: The occurrence of the second mesiobuccal canal (MB2) in permanent maxillary first molars is more common than in the second molars. Microscopic assessment proves to be more effective than naked eye assessment for detecting the presence of MB2 in both maxillary first and second molars.
J Bangladesh Coll Phys Surg 2024; 42: 133-138
Pelaksanaan Pelayanan Publik Di Kantor Desa Karang Anyar Kecamatan Semendawai Timur
Authors: Ibrahim Ibrahim , Niswah Choirun , Efendi Aris 
Published: April 2024

Abstract: This research is entitled "Implementation of Public Services at the Karang Anyar Village Office, East Semendawai Subdistrict." The problems that have occurred are that administrative services for population in the village face difficulties in processing the issuance of Family Cards (KK), errors, and a lack of availability of administrative services such as ID cards (KTP), Family Cards (KK), and Birth Certificates. The research method used is qualitative with descriptive characteristics. Data collection techniques include observation, interviews, and documentation. The collected data is then analyzed and presented or data reduction is performed, followed by drawing conclusions. The results of this study show that the implementation of public services has been carried out quite well through several indicators. This includes the reliability of employees who are skilled in using service process aids, reliability seen from their level of education, reliability derived from a wealth of knowledge and experience, and more. Additionally, there is responsiveness in quickly responding to service requests, providing assurance in service delivery, and ensuring timeliness. There is empathy in understanding the needs of the community and attempting to understand their complaints. There are tangible facilities for service at the Karang Anyar Village Office. Furthermore, factors affecting service implementation include the availability of resources, employee awareness, and community support.Keywords: Implementation, Public ServicesAbstrak: Penelitian ini berjudul Pelaksanaan Pelayanan Publik di Kantor Desa Karang Anyar Kecamatan Semendawai Timur. Adapun permasalahan yang terjadi, yaitu pelayanan administrasi kependudukan di desa tersebut memiliki kesulitan dalam mengurus pembuatan KK, kesalahan dan kurangnya penyediaan layanan administrasi KTP, KK, Akte Kelahiran. Metode penelitian yang digunakan adalah kualitatif dengan karakteristik deskriptif. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Data yang diperoleh kemudian dianalisis dan disajikan kembali atau direduksi data lalu disajikan kemudian ditarik kesimpulan. Hasil penelitian ini menunjukan bahwasanya proses pelaksanaan pelayanan publik sudah dilaksanakan cukup baik melalui beberapa indikator, yaitu dengan melaksanakan kehandalan para pegawai yang handal dalam menggunakan alat bantu proses pelayanan, handal yang dilihat dari jenjang pendidikan, handal yang dimiliki dari banyak wawasan dan pengalaman, dan lainnya. Kemudian ketanggapan dalam merespon cepat pelayanan. Memberikan jaminan dalam pelayanan, jaminan tepat waktu. Empati dengan mengetahui kebutuhan masyarakat, mencoba memahami keluhan masyarakat. Kemudian, berwujud yang berupa fasilitas pelayanan di kantor desa Karang Anyar. Selanjutnya faktor-faktor yang mempengaruhi pelaksanaan pelayanan dengan adanya sarana yang tersedia, faktor kesadaran pegawai, dan juga dukungan dari masyarakat.Kata Kunci: Pelaksanaan, Pelayanan Publik
Manajemen Pengelolaan Kelas Pada Satuan PAUD SINAR PAGI Desa Maras Tengah Kabupaten Seluma
Authors: Suwarni Suwarni , Haryono Mimpira 
Published: April 2024

Abstract: to describe classroom management at the SINAR PAGI PAUD Unit in Maras Tengah Village, Seluma Regency. The method used in this research is a qualitative research method, a method based on the philosophy of postpositivism, used to research natural objects, where the researcher is the key instrument. The data collection technique was carried out by triangulation (combination). Data analysis is inductive or qualitative and research results emphasize meaning rather than generalization. The results of classroom management research at the SINAR PAGI PAUD Unit in Maras Tengah Village, Seluma Regency are good. The importance of classroom management, where classroom management is a factor that can create and maintain a classroom atmosphere and conditions so that it always looks effective. The creation of an effective classroom atmosphere has a major influence on the ongoing effective learning process. With good classroom management, no time is wasted just because the classroom situation is out of control.Keywords: Classroom Management, PAUD.Abstrak: untuk mendeskripsikan manajemen pengelolaan kelas pada Satuan PAUD SINAR PAGI Desa Maras Tengah Kabupaten Seluma. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif adalah metode yang berlandaskan pada filsafat postpositivisme, digunakan untuk meneliti pada objek alamiah, dimana peneliti adalah sebagai instrumen kunci. Teknik pengumpulan data dilakukan dengan cara triangulasi (gabungan). analisa data bersifat induktif atau kualitatif dan hasil penelitian lebih menekankan makna dari pada generalisasi. Hasil penelitian manajemen pengelolaan kelas pada Satuan PAUD SINAR PAGI Desa Maras Tengah Kabupaten Seluma sudah baik. Pentingnya pengelolaan kelas dimana manajemen kelas merupakan faktor yang dapat menciptakan dan mempertahankan suasana serta kondisi kelas agar selalu tampak efektif. Terciptanya suasana kelas yang efektif memiliki pengaruh besar terhadap berlangsungnya proses pembelajaran yang efektif. Dengan manajemen kelas yang baik, tidak ada waktu yang terbuang percuma hanya karena situasi kelas yang tidak terkendali.Kata Kunci: Manajemen Pengelolaan Kelas, PAUD.
AN UNFINISHED POLEMICS “AMONG OURSELVES”
Authors: Ilnytskyi Mykola 
Published: April 2024

The paper examines the polemical dialogue on the national question between two Ukrainian literary classics, Ivan Franko and Lesia Ukrainka, which took place in the late 19th and early 20th century, as well as its impact on other writers, social, and political figures. There was a noticeable divergence in the positions of two prominent writers, with Ivan Franko criticizing the trans-Dnieper Ukrainian intellectuals for distancing themselves from the people, while Lesia Ukrainka justified their participation in the statewide all-Russian movement. This is primarily explained by the asynchrony of social development in the conditions of the Russian autocratic empire and the Austro-Hungarian constitutional state, but there was still another factor. The views of both Ivan Franko and Lesia Ukrainka were formed under the influence of the social-democratic ideas of Mykhailo Drahomanov. However, by that time, Ivan Franko had already shifted towards national positions, while Lesia Ukrainka continued to share Drahomanov’s principles. The evolution of Lesia Ukrainka’s views suggests that it was rather a temporary misunderstanding than an ideological confrontation with Ivan Franko. During the Soviet period, this opposition articulated by Ivan Franko as the one “among ourselves” and temporary “polemical controversy” (Lesіa Ukrainka) was intentionally ignored, as the communist regime in the USSR made efforts to silence the presence of national movements. Interest in this polemic appeared already in the first post-revolutionary years in Ukraine (Mykhailo Drai-Khmara) and remained vivid within the Ukrainian emigration (Dmytro Dontsov, Yurii Lavrinenko). Subsequently, it was revived in literary works during the period of Ukrainian state independence, with contributions from Ivan Denysiuk, Mykhailo Nechytaliuk, Vasyl Horyn, Halyna Levchenko, Mykhailo Hnatiuk, and Bohdan Tykholoz. The polemic between Ivan Franko and Lesia Ukrainka proves its relevance in current circumstances as well.
Ovarian Yolk Sac Tumor pada Usia Tua ; A Rare Case
Authors: Kusumardani Dini , Mayorita Pamelia , Novianti Hera 
Published: April 2024

Pendahuluan: Yolk sac tumor merupakan subtipe paling umum kedua atau sekitar 15-20% dari semua germ cell tumor yang biasanya ditemukan pada wanita usia muda.1Yolk sac tumor ini jarang terjadi pada wanita usia tua atau postmenopause, dapat berupa komponen yolk sac murni atau campuran dengan komponen tumor epitel lainnya. Laporan Kasus: Kami melaporkan seorang wanita usia 54 tahun dengan keluhan perut membesar seperti full- term pregnancy. Hasil pemeriksaan USG adalah tumor ovarium. Hasil pemeriksaan laboratorium menunjukkan dalam batas normal. Pasien menjalani prosedur optimal debulking. Pemeriksaan histopatologi adalah Ovarian Yolk Sac Tumor. Kesimpulan: Meskipun kasus ini jarang terjadi, Ovarian Yolk Sac Tumor dapat ditemukan pada usia tua atau postmenopause yang umumnya murni atau campuran dengan tumor epitel lainnya, pada kasus ini ditemukan Yolk Sac Tumor ovarium murni. Diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, pemeriksaan radiologis dan pemeriksaan histopatologis. Pemeriksaan histopatologis merupakan gold standard untuk diagnosis Ovarian Yolk Sac Tumor. Diagnosis bandingnya adalah Immature Teratoma, Sclerosing Stromal Tumor dan Dermoid Cyst. Kecurigaan klinis yang tinggi, diagnosis dan penatalaksanaan yang cepat dapat memberikan prognosis yang baik.
Pemanfaatan Minyak Kenanga (Cananga Odorata) untuk Pencegahan Depresi Lansia pada Masa Covid-19 di Panti Jompo Sumatera Barat
Authors: Desnita Eka , Yesika Relin 
Published: April 2024

Pendahuluan: Pandemi COVID-19 berdampak pada kesehatan mental orang-orang di seluruh dunia. Dimasa pandemi COVID-19, ketakutan, kekhawatiran, stres atau depresi adalah respons normal terhadap ancaman yang dirasakan pada saat dihadapkan pada ketidakpastian. Di Indonesia survei yang dilakukan oleh Perhimpunan Dokter Spesialis Kedokteran Jiwa Indonesia diikuti oleh 2.364 orang, sebanyak 69% responden menyatakan memiliki masalah psikologis terkait pandemi COVID-19 berupa cemas (68%), depresi (67%) dan trauma psikologis (77%). Tujuan: Minyak esensial telah banyak digunakan untuk aromaterapi sebagai antidepresan yang dapat menurunkan tingkat depresi seseorang. Salah satu minyak esensial yang digunakan untuk aromaterapi adalah minyak kenanga (Cananga odorata). Minyak esensial kenanga memiliki kandungan kimia seperti geraniol, eugenol dan linalool yang di duga memiliki aktivitas antidepresan. Metoda: Penelitian ini merupakan penelitian pre-experimental one group pre-test post-test design dengan diberikan pre-test sebelum perlakuan dan post-test setelah diberi perlakuan. Perlakuan yang dimaksud adalah pemberian aromaterapi dengan konsentasi 2% selama 10 menit/ hari selama 7 hari. Penelitian ini dilakukan di tiga panti jompo yang tersebar diseluruh Sumatera Barat. Populasi penelitian ini adalah 45 orang lansia yang tinggal di tiga panti jompo di Sumatera Barat. Pengumpulan data menggunakan Geriatric Depression Scale-15 Form untuk mengukur tingkat depresi pada lansia. Hasil: Hasil penelitian menunjukan pada saat dilakukan pre-test terdapat hasil sebagai berikut depresi ringan 26,6%, depresi sedang 37,8% dan depresi berat 35,5%. Pada saat setelah pemberian aromaterapi dilakukan post-test dengan hasil sebagai berikut terdapat depresi ringan 66,7%, depresi sedang 11,1%, depresi berat 6,7% dan lansia yang tidak memperhatinkan yaitu sebanyak 15,5%. Kesimpulan: Hasil uji non parametrik Wilcoxon diperoleh signifikan 0.000 < 0.05, sehingga dapat disimpulkan terdapat pengaruh minyak kenanga (Cananga odorata) dalam menurunkan dan mencegah depresi lansia pada masa COVID- 19 di Panti Jompo yang terdapat di Sumatera Barat.
Prosedur BPJS dan Klaim BPJS oleh Rumah Sakit
Authors: Amran Rika 
Published: April 2024

Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan) merupakan badan hukum resmi yang menjamin penyelenggaraan jaminan sosial kesehatan untuk seluruh masyarakat Indonesia agar sistem jaminan sosial dapat dilaksanakan dengan baik. Penyelenggaraan Jaminan Kesehatan merupakan bentuk pelayanan kesehatan yang bersifat menyeluruh sesuai dengan kebutuhan medik dan mengikuti standar pelayanan medik. Untuk jasa yang telah diberikan Rumah sakit kepada peserta BPJS dapat dilakukan klaim BPJS kesehatan dana perawatan pasien BPJS terhadap BPJS. Tagihan klaim dari Rumah Sakit ke BPJS dilakukan secara kolektif setiap bulan dimana Rumah Sakit berkewajiban dalam menyerahkan dokumen-dokumen pendukung yaitu kwitansi pembayaran, formulir bukti pelayanan rawat jalan dan persyaratan, pemeriksaan penunjang, serta Surat Eligibilitas Peserta (SEP) dan grouper INA CBG’S. Grouper INA CBG’S yaitu pemberlakuan tarif yang mengacu pada Indonesa Case Base Group (INA CBG’S) berupa sebuah software yang digunakan Rumah Sakit untuk mengajukan klaim kepada pemerintah dalam pembayaran klaim BPJS dengan skema casemix. Casemix memiliki peran dalam pengelompokkan diagnosis penyakit untuk penghitungan biaya pelayanan pasien di Rumah Sakit.
Skrening Hipertensi dengan Analisa Heart Rate Variability
Authors: Kartika Ronald Winardi , Atmaja Yuvensius Gerry , Suparto Suparto , Hartanto Hartanto , Sutanti Yosephin Sri 
Published: April 2024

Latar Belakang:Tekanan darah merupakan pengukuran fundamental bagi kesehatan sistem kardiovaskular yang dapat menjadi indikator penyakit hipertensi kardiovaskular yang merupakan penyebab utama kematian dan kecacatan pada tahun 2017. Riset Kesehatan Derah (RISKESDAS) pada tahun 2018 menunjukkan adanya kenaikan prevalensi hipertensi menurut pengukuran pada penduduk yang umurnya >18 tahun di dapatkan 25,8% menjadi 34,1%. Hal tersebut menjadi latar belakang dari penelitian ini untuk skrening hipertensi pada pekerja di Rumah Sakit Ukrida dengan analisa heart rate variability. Metode: Pengambilan data dengan consecutive purposive sampling. Didapatkan sebanyak 81 sampel penelitian yang telah memenuhi kriteria inklusi dan ekslusi. Setiap sampel dilakukan pemeriksaan tekanan darah dan Heart Rate Variability (HRV) sebanyak tiga kali dan dilakukan nilai rerata. Hasil: Mayoritas subyek penelitian adalah perempuan sejumlah 43 subyek (53,1%) dengan kelompok usia kelompok 20-30 tahun tertinggi, 44 subyek (54,3%). Kategori pekerjaan terbanyak adalah perawat sebanyak 29 subyek (35,8%) Subyek yang memiliki tekanan darah yang normal, yaitu 41 responden (50,6%), prahipertensi 35 subyek ( (43.2%) dan hipertensi 5 subyek (6.2%). Uji korelesi pada subyek pra hipertensi didapatkan nilai SDNN nilai 20-30 ms (awareness) sebanyak 16 subyek (19,8%) dengan nilai korekasi 0.510 (korelasi sedang). Evaluasi nilai RMSDD pada subyek pra hipertensi didapatkan nilai 10-20 ms (awareness) sebanyak 13 (16,1%) subyek dengan nilai korelasi pearson 0,471( korelasi sedang). Kesimpulan: Tekanan darah mempunyai korelasi positif dengan pengukuran HRV ( nilai SDNN dan RMSDD ) pemeriksaan HRV dapat digunakan sebagai salah satu metode untuk deteksi dini pada penderita pra hipertensi pada pekerja RS UKRIDA.
Perbandingan Efektivitas Infusa Bunga Lawang (Illicium Verum) dan Infusa Daun Kunyit Terhadap Mortalitas Larva Aedes aegypti Instar III
Authors: Triyana Rahma , Adelin Prima , Ruhsyahadati Ruhsyahadati , Helmizar Roland 
Published: April 2024

Pendahuluan: Nyamuk Aedes sp merupakan vektor penyebab penyakit Demam Berdarah (DBD) yang menginfeksi jutaan orang setiap tahunnya. Salah satu penanganan DBD yaitu membasmi vektor dengan cara pemberian insektisida alami pada larva nyamuk. Bunga Lawang (Illicium verum) dan daun kunyit berpotensi sebagai larvasida alami. Tujuan: Membandingkan efektivitas larvasida infusa bunga lawang dan daun kunyit terhadap mortalitas larva Aedes aegypti. Metode: Penelitian eksperimental menggunakan rancangan Post Test Only Control Group Design, populasi terjangkau penelitian ini adalah larva Aedes aegypti instar III dengan kebutuhan total sampel 560 larva, analisa data menggunakan uji one way anova. Hasil penelitian: Infusa bunga lawang efektif membunuh larva Aedes aegypti instar III pada konsentrasi 2% selama 24 jam dengan kematian sebanyak 8,75%, konsentrasi 32% sebanyak 100% dalam waktu 24 jam sedangkan kematian larva pada konsentrasi infusa daun kunyit sebesar 30% dalam 24 jam sebanyak 2,5%, pada konsentrasi 100% selama 24 jam kematian larva hanya mencapai 17,5%. Kesimpulan: Infusa bunga lawang lebih efektif sebagai larvasida dibandingkan infusa daun kunyit.
Reproductive factors and cardiometabolic disease among middle-aged and older women: a nationwide study from CHARLS
Authors: Wang Qiong , Pang Bo , Wu Jing , Li Chunyan , Niu Wenquan 
Published: April 2024

BackgroundCardiometabolic disease is skyrocketing to epidemic proportions due to the high prevalence of its components and the aging of the worldwide population. More efforts are needed to improve cardiometabolic health. The aim of this nationally representative study based on the China Health and Retirement Longitudinal Study (CHARLS, 2014–2018) was to examine the association between reproductive factors and cardiometabolic disease among Chinese women aged ≥45 years.MethodsThe CHARLS is an ongoing longitudinal study initiated in 2011, and the latest follow-up was completed in 2018. In total, 6,407 participants were analyzed. Effect-sizes are expressed as odds ratios (OR) and 95% confidence intervals (CI). Confounding was considered from statistical adjustment, subsidiary exploration, and unmeasured confounding assessment aspects.ResultsOf 6,407 accessible participants, 60.9% were recorded as having one or more of five predefined cardiovascular or metabolic disorders. Compared to those with two children, participants who had 0–1 child were found to have a lower risk of cardiometabolic disease (OR = 0.844, 95% CI: 0.714–0.998), and those who had ≥3 children had a greater risk (OR = 1.181, 95% CI: 1.027–1.357). Age at menarche of 16–18 years was a protective factor compared with ≤16 years of age (OR = 0.858, 95% CI: 0.749–0.982). In contrast, participants with a history of abortion were 1.212 times more likely to have cardiometabolic disorders (OR = 1.212, 95% CI: 1.006–1.465). The likelihood for the presence of unmeasured confounding was low, as reflected by E-values.ConclusionsOur findings demonstrate that number of children, age at menarche, and history of abortion were associated with a significant risk of cardiometabolic disease among Chinese women aged ≥45 years.
The influence of cortisol co-secretion on clinical characteristics and postoperative outcomes in unilateral primary aldosteronism
Authors: Jiang Yiran , Zhou Lihua , Zhang Cui , Su Tingwei , Jiang Lei , Zhou Weiwei , Zhong Xu , Wu Luming , Wang Weiqing 
Published: April 2024

ContextThe prevalence of unilateral primary aldosteronism (UPA) with cortisol co-secretion varies geographically.ObjectiveTo investigate the prevalence and clinical characteristics of UPA with cortisol co-secretion in a Chinese population.DesignRetrospective cohort study.MethodsWe recruited 580 patients with UPA who underwent cosyntropin stimulation test (CST) after the 1-mg dexamethasone suppression test (DST) and retrospectively analyzed the clinical characteristics and postoperative outcomes of UPA with and without cortisol co-secretion.ResultsUPA with cortisol co-secretion (1 mg DST&gt;1.8 ug/dL) was identified in 65 of 580 (11.2%) patients. These patients were characterized by older age, longer duration of hypertension, higher concentration of plasma aldosterone and midnight cortisol, lower adrenocorticotropic hormone (ACTH) and dehydroepiandrosterone sulfate (DHEAS), larger tumor diameter, and more history of diabetes mellitus. Cortisol and aldosterone levels were higher and DHEAS level was lower in UPA with cortisol co-secretion at 0–120 min after CST. Among 342 UPA patients with KCNJ5 gene sequencing and follow-up results, the complete clinical success rate was lower in UPA with cortisol co-secretion (33.3% vs. 56.4%, P&lt;0.05); the complete biochemical success rate and KCNJ5 mutation did not differ between the two groups. Age, tumor size, and ACTH were independent predictors of UPA with cortisol co-secretion. Sex, BMI, duration of hypertension, KCNJ5 mutation, and cortisol co-secretion were independent predictors for complete clinical success in UPA after surgery.ConclusionsUPA with cortisol co-secretion is not uncommon in China, but the clinical features were distinctly different from those without co-secretion. Cortisol co-secretion is an independent risk factor for incomplete clinical success after surgery in UPA.
Isolation and characterization of Hc-targeting chimeric heavy chain antibodies neutralizing botulinum neurotoxin type B
Authors: Jiang Yujia , Wang Rong , Guo Jiazheng , Cheng Kexuan , Chen Lei , Wang Xi , Li Yating , Du Peng , Gao Chen , Lu Jiansheng , Yu Yunzhou , Yang Zhixin 
Published: April 2024

BackgroundBotulinum neurotoxin (BoNT) produced by Clostridium botulinum is one of the most potent known toxins. Moreover, BoNT is classified as one of the most important biological warfare agents that threatens the biosafety of the world. Currently, the approved treatment for botulism in humans is the use of polyvalent horse serum antitoxins. However, they are greatly limited because of insufficient supply and adverse reactions. Thus, treatment of human botulism requires the development of effective toxin-neutralizing antibodies. Considering their advantages, neutralizing nanobodies will play an increasing role as BoNTs therapeutics.MethodsHerein, neutralizing nanobodies binding to the heavy chain (Hc) domain of BoNT/B (BHc) were screened from a phage display library. Then, BoNT/B-specific clones were identified and fused with the human Fc fragment (hFc) to form chimeric heavy chain antibodies. Finally, the affinity, specificity, and neutralizing activity of antibodies against BoNT/B in vivo were evaluated.ResultsThe B5-hFc, B9-hFc and B12-hFc antibodies demonstrated high affinity for BHc in the nanomolar range. The three antibodies were proven to have potent neutralizing activity against BoNT/B in vivo.ConclusionThe results demonstrate that inhibiting toxin binding to the host receptor is an efficient strategy and the three antibodies could be used as candidates for the further development of drugs to prevent and treat botulism.