bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Lipoprotein Subfraction and Size Measurements in Prediction of Mortality in Maintenance Hemodialysis Patients
Authors: Noori Nazanin , Caulfield Michael P. , Salameh Wael A. , Reitz Richard E. , Nicholas Susanne B. , Molnar Miklos Z. , Nissenson Allen R. , Kovesdy Csaba P. , Kalantar-Zadeh Kamyar 
Published: October 2011

Summary

Background and objectives
Conventional lipid profiles usually cannot predict cardiovascular outcomes in chronic disease states. We hypothesized that novel lipoprotein subfraction concentrations and LDL particle size measurements better predict mortality in maintenance hemodialysis (MHD) patients.

Design, setting, participants, & measurements
Mortality-predictability of LDL particle diameter and lipoprotein subfraction concentrations, measured by novel ion mobility, was examined in a cohort of 235 hemodialysis patients who were followed for up to 6 years using Cox models with adjustment for important covariables.

Results
Patients were 54 ± 14 years old (mean ± SD) and included 45% women with total, LDL and HDL cholesterol levels of 143 ± 42, 76 ± 29, and 37 ± 12 mg/dl, respectively. Over 6 years, 71 patients (31%) died. Conventional lipid profile was not associated with mortality. The death hazard ratio (HR, 95% confidence interval) of the highest versus lowest quartiles of very small and large LDL particle concentrations were 2.43 (1.03 to 5.72) and 0.38 (0.15 to 0.96), respectively. Across increasing quartiles of LDL particle diameter, death HRs were 1.00, 0.93 (0.46 to 1.87), 0.43 (0.21 to 0.89), and 0.45 (0.31 to 1.00), respectively.

Conclusions
Whereas conventional lipid profile cannot predict mortality in MHD patients, larger novel LDL particle diameter or higher large LDL particle concentrations appear predictive of greater survival, whereas higher very small LDL particle concentration is associated with higher death risk. Examining lipoprotein subfraction modulation in chronic diseases is indicated.
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
Authors: Narayana Ashwatha , Gruber Deborah , Kunnakkat Saroj , Golfinos John G. , Parker Erik , Raza Shahzad , Zagzag David , Eagan Patricia , Gruber Michael L. 
Published: October 2011

Object
The presence of angiogenesis is a hallmark of glioblastoma (GBM). Vascular endothelial growth factor (VEGF), which drives angiogenesis, provides an additional target for conventional therapy. The authors conducted a prospective clinical trial to test the effectiveness of bevacizumab, an inhibitor of VEGF, in newly diagnosed GBM.

Methods
From 2006 through 2010, 51 eligible patients with newly diagnosed GBM were treated with involved-field radiation therapy and concomitant temozolomide (75 mg/m2 daily for 42 days) along with bevacizumab (10 mg/kg every 2 weeks), starting 29 days after surgery. This was followed by 6 cycles of adjuvant temozolomide therapy (150 mg/m2 on Days 1–7 of a 28-day cycle) with bevacizumab administered at 10 mg/kg on Days 8 and 22 of each 28-day cycle.

Results
The 6- and 12-month progression-free survival (PFS) rates were 85.1% and 51%, respectively. The 12- and 24-month overall survival (OS) rates were 85.1% and 42.5%, respectively. Grade III/IV toxicities were noted in 10 patients (19.6%). No treatment-related deaths were observed. Asymptomatic intracranial bleeding was noted in 5 patients.

Conclusions
The addition of bevacizumab to conventional therapy in newly diagnosed GBM appears to improve both PFS and OS in patients with newly diagnosed GBM, with acceptable morbidity. A shift toward diffuse relapse was noted in a significant number of patients. Ongoing Phase III clinical trials will show the true benefit of this antiangiogenic approach.
Antiplane Wave Scattering from a Cylindrical Void in a Pre-Stressed Incompressible Neo-Hookean Material
Authors: Parnell William J. , David Abrahams I. 
Published: October 2011

AbstractAn isolated cylindrical void is located inside an incompressible nonlinear-elastic medium whose constitutive behaviour is governed by a neo-Hookean strain energy function. In-plane hydrostatic pressure is applied in the far-field so that the void changes its radius and an inhomogeneous region of deformation arises in the vicinity of the void. We consider scattering from the void in the deformed configuration due to an incident field (of small amplitude) generated by a horizontally polarized shear (SH) line source, a distance r0 (R0) away from the centre of the void in the deformed (undeformed) configuration. We show that the scattering coefficients of this scattered field are unaffected by the pre-stress (initial deformation). In particular, they depend not on the deformed void radius a or distance r0, but instead on the original void size A and original distance R0.
Non-Matching Grids for a Flexible Discretization in Computational Acoustics
Authors: Flemisch Bernd , Kaltenbacher Manfred , Triebenbacher Simon , Wohlmuth Barbara 
Published: October 2011

AbstractFlexible discretization techniques for the approximative solution of coupled wave propagation problems are investigated. In particular, the advantages of using non-matching grids are presented, when one subregion has to be resolved by a substantially finer grid than the other subregion. We present the non-matching grid technique for the case of a mechanical-acoustic coupled as well as for acoustic-acoustic coupled systems. For the first case, the problem formulation remains essentially the same as for the matching situation, while for the acoustic-acoustic coupling, the formulation is enhanced with Lagrange multipliers within the framework of Mortar Finite Element Methods. The applications will clearly demonstrate the superiority of the Mortar Finite Element Method over the standard Finite Element Method both concerning the flexibility for the mesh generation as well as the computational time.
Perfectly Matched Layer with Mixed Spectral Elements for the Propagation of Linearized Water Waves
Authors: Cohen Gary , Imperiale Sébastien 
Published: October 2011

AbstractAfter setting a mixed formulation for the propagation of linearized water waves problem, we define its spectral element approximation. Then, in order to take into account unbounded domains, we construct absorbing perfectly matched layer for the problem. We approximate these perfectly matched layer by mixed spectral elements and show their stability using the “frozen coefficient” technique. Finally, numerical results will prove the efficiency of the perfectly matched layer compared to classical absorbing boundary conditions.
Transparent Boundary Conditions for Elastic Anisotropic VTI Media: Axially Symmetric Case
Authors: Podgornova Olga 
Published: October 2011

AbstractTransparent boundary conditions (TBCs) for anisotropic vertical transverse isotropic VTI medium are formulated for the axially symmetric case. The high accuracy of the derived TBCs and their long-time stability are demonstrated in numerical experiments. The TBCs are represented in terms of the vertical component of the velocity vector and tangential component of the stress tensor that facilitates the easy implementation of the boundary condition into the finite-difference staggered-grid scheme.
Micro-Differential Boundary Conditions Modelling the Absorption of Acoustic Waves by 2D Arbitrarily-Shaped Convex Surfaces
Authors: Barucq Hélène , Diaz Julien , Duprat Véronique 
Published: October 2011

AbstractWe propose a new Absorbing Boundary Condition (ABC) for the acoustic wave equation which is derived from a micro-local diagonalization process formerly defined by M.E. Taylor and which does not depend on the geometry of the surface bearing the ABC. By considering the principal symbol of the wave equation both in the hyperbolic and the elliptic regions, we show that a second-order ABC can be constructed as the combination of an existing first-order ABC and a Fourier-Robin condition. We compare the new ABC with other ABCs and we show that it performs well in simple configurations and that it improves the accuracy of the numerical solution without increasing the computational burden.
Negotiating a Korean National Myth: Dialogic Interplay and Entextualization in an Ethnographic Encounter
Authors: Yun Kyoim 
Published: October 2011

Abstract
This article examines a discordant, collaborative telling of Korea’s founding myth, one accomplished by a traditional singer and two native folklorists, including myself. Highlighting the discursive and intertextual construction of talk, I demonstrate how the event’s participants coped with different agendas as we evaluated each other and negotiated our expectations regarding the myth’s content and performance. I argue that dissonant ethnographer-performer interactions such as this one warrant more study. Scholarly attention to the ways specific events and texts develop can help us better understand negotiations of power, authority, and participant roles, as well as the intertextual and intersubjective relations that constitute ethnographic encounters.
Synthesis and characterization of N‐ and O‐alkylated poly[aniline‐co‐N‐(2‐hydroxyethyl) aniline]
Authors: Shadi Leyla , Gheybi Homa , Entezami Ali Akbar , Safa Kazem D. 
Published: October 2011

AbstractPoly[aniline‐co‐N‐(2‐hydroxyethyl) aniline] was synthesized in an aqueous hydrochloric acid medium with a determined feed ratio by chemical oxidative polymerization. This polymer was used as a functional conducting polymer intermediate because of its side‐group reactivity. To synthesize the alkyl‐substituted copolymer, the initial copolymer was reacted with NaH to obtain the N‐ and O‐anionic copolymer after the reaction with octadecyl bromide to prepare the octadecyl‐substituted polymer. The microstructure of the obtained polymers was characterized by Fourier transform infrared spectroscopy, 1H‐NMR, and X‐ray diffraction. The thermal behavior of the polymers was investigated by thermogravimetric analysis and differential scanning calorimetry. The morphology of obtained copolymers was studied by scanning electron microscopy. The cyclic voltammetry investigation showed the electroactivity of poly [aniline‐co‐N‐(2‐hydroxyethyl) aniline] and N and O‐alkylated poly[aniline‐co‐N‐(2‐hydroxyethyl) aniline]. The conductivities of the polymers were 5 × 10−5 S/cm for poly[aniline‐co‐N‐(2‐hydroxyethyl) aniline] and 5 ×10−7 S/cm for the octadecyl‐substituted copolymer. The conductivity measurements were performed with a four‐point probe method. The solubility of the initial copolymer in common organic solvents such as N‐methyl‐2‐pyrrolidone and dimethylformamide was greater than polyaniline. The alkylated copolymer was mainly soluble in nonpolar solvents such as n‐hexane and cyclohexane. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Carboxybetaine, sulfobetaine, and cationic block copolymer coatings: A comparison of the surface properties and antibiofouling behavior
Authors: Wu Lin , Jasinski Jacek , Krishnan Sitaraman 
Published: October 2011

AbstractTwo different zwitterionic block copolymers (BCs) and a cationic BC were synthesized from the same BC precursor, which consisted of a polystyrene (PS) block and a poly[N‐(3‐dimethylamino‐1‐propyl)acrylamide] block. The zwitterionic BCs contained the dimethylammonioacetate (carboxybetaine) and dimethylammoniopropyl sulfonate (sulfobetaine) groups. Thin films cast from these polymers were investigated for surface wettability, surface charge, and protein adsorption. Surface‐energy parameters calculated with advancing contact angle (θa) and receding contact angle (θr) of different probe liquids showed that it was θr and not θa that was representative of the polar/ionic groups in the near‐surface regions of the coatings. Electrophoretic mobility was used to characterize the influence of pH on the net surface charge. In aqueous dispersions, the carboxybetaine polymer showed an ampholyte behavior with an isoelectric point of 6, whereas the sulfobetaine polymer was found to be anionic at all pH values between 2 and 10. Protein adsorption on the carboxybetaine BC was relatively independent of the net charges on the protein or the polymer, but the negatively charged sulfobetaine polymer showed a higher adsorption of positively charged protein molecules. Regardless of the net protein charge, both zwitterionic coatings adsorbed less protein compared to the PS and poly(2,3,4,5,6‐pentafluorostyrene) controls. The sulfobetaine and cationic BCs adsorbed higher amounts of oppositely charged protein molecules than like‐charged protein molecules. However, the adsorption of oppositely charged protein was much higher on the cationic surface than on the sulfobetaine surface. The zwitterionic BCs, particularly the carboxybetaine polymer, from this article are expected to function as stable, low‐fouling surface modifiers in different biological environments. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Injection‐molded high‐density polyethylene–hydroxyapatite–aluminum oxide hybrid composites for hard‐tissue replacement: Mechanical, biological, and protein adsorption behavior
Authors: Tripathi Garima , Basu Bikramjit 
Published: October 2011

AbstractIn this article, we report the mechanical and biocompatibility properties of injection‐molded high‐density polyethylene (HDPE) composites reinforced with 40 wt % ceramic filler [hydroxyapatite (HA) and/or Al2O3] and 2 wt % titanate as a coupling agent. The mechanical property measurements revealed that a combination of a maximum tensile strength of 18.7 MPa and a maximum tensile modulus of about 855 MPa could be achieved with the injection‐molded HDPE–20 wt % HA–20 wt % Al2O3 composites. For the same composite composition, the maximum compression strength was determined to be 71.6 MPa and the compression modulus was about 660 MPa. The fractrography study revealed the uniform distribution of ceramic fillers in the semicrystalline HDPE matrix. The cytocompatibility study with osteoblast‐like SaOS2 cells confirmed extensive cell adhesion and proliferation on the injection‐molded HDPE–20 wt % HA–20 wt % Al2O3 composites. The cell viability analysis with the 3(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay revealed a statistically significant difference between the injection‐molded HDPE–20 wt % HA–20 wt % Al2O3 composites and sintered HA for various culture durations of upto 7 days. The difference in cytocompatibility properties among the biocomposites is explained in terms of the difference in the protein absorption behavior. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Effect of reactive poly(ethylene glycol) flexible chains on curing kinetics and impact properties of bisphenol‐a glycidyl ether epoxy
Authors: Yao Dahu , Kuila Tapas , Sun Kyung‐Bok , Kim Nam‐Hoon , Lee Joong‐Hee 
Published: October 2011

AbstractBisphenol‐A glycidyl ether epoxy resin was modified using reactive poly(ethylene glycol) (PEO). Dynamic mechanical analysis showed that introducing PEO chains into the structure of the epoxy resin increased the mobility of the molecular segments of the epoxy network. Impact strength was improved with the addition of PEO at both room (RT) and cryogenic (CT, 77 K) temperature. The curing kinetics of the modified epoxy resin with polyoxypropylene diamines was examined by differential scanning calorimetry (DSC). Curing kinetic parameters were determined from nonisothermal DSC curves. Kinetic analysis suggested that the two‐parameter autocatalytic model suitably describes the kinetics of the curing reaction. Increasing the reactive PEO content decreased the heat flow of curing with little effect on activation energy (Ea), pre‐exponential factor (A), or reaction order (m and n). © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Mechanistic study on carboxymethyl hydroxyethyl cellulose as fluid loss control additive in oil well cement
Authors: Bülichen Daniel , Plank Johann 
Published: October 2011

AbstractThe working mechanism of carboxymethyl hydroxyethyl cellulose (CMHEC, Mw 2.6 × 105 g/mol) as fluid loss control additive (FLA) for oil well cement was investigated. First, characteristic properties of CMHEC such as anionic charge amount, intrinsic viscosity in cement pore solution, and static filtration properties of cement slurries containing CMHEC were determined at 27°C and 70 bar. Effectiveness of the FLA was found to rely on reduction of cement filter cake permeability. Consequently, the working mechanism is ascribed to constriction of cement filter cake pores. Zeta potential measurements confirm that at low CMHEC dosages (0–0.3% by weight of cement, bwoc), adsorption of the polymer onto the surface of hydrating cement occurs. However, at dosages of 0.4% bwoc and higher, an associated polymer network is formed. This was evidenced by a strong increase in hydrodynamic diameter of solved CMHEC molecules, an exponential increase in viscosity and a noticeable reduction of surface tension. Thus, the working mechanism of CMHEC changes with dosage. At low dosages, adsorption presents the predominant mode of action, whereas above a threshold concentration of ∼ 10 g/L (the “overlapping concentration”), formation of associated polymer networks is responsible for effectiveness of CMHEC. Addition of anionic polyelectrolytes (e.g., sulfonated melamine formaldehyde polycondensate, Mw 2.0 × 105 g/mol) to cement slurries containing CMHEC greatly improves fluid loss control. Apparently, the presence of such polyelectrolytes causes the formation of colloidal associates from CMHEC to occur at lower dosages. Through this mechanism, effectiveness of CMHEC as cement fluid loss additive is enhanced. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Influence of novel surface modifying macromolecules and coagulation media on the gas permeation properties of different polymeric gas separation membranes
Authors: Savoji Houman , Rana Dipak , Matsuura Takeshi , Soltanieh Mohammad , Tabe Shahram 
Published: October 2011

AbstractIntegrally skinned asymmetric membranes for the separation of O2 and N2 were fabricated by the phase inversion technique from polysulfone, polyetherimide, and polyimide. Two types of surface modifying macromolecules (SMMs) including hydrophilic SMM (LSMM) and charged SMM (cSMM) were synthesized and blended with the casting solution to modify the membrane surface. The cast film was then immersed in the first coagulant alcohol (methanol, ethanol, or isopropanol) for a predetermined period, before being immersed in the second coagulant (water). The SMMs used in these experiments were laboratory synthesized by the two‐step process of polyurethane prepolymer synthesis and end capping, before being characterized by differential scanning calorimetry. Their molecular structure was determined from the molecular weight obtained by gel permeation chromatography. The membranes were characterized by contact angle measurement and O2 and N2 gas permeation performance. Attempts were made to interpret the gas permeation data by delayed demixing affected by solubility parameters of polymer, solvent, and nonsolvent. Furthermore, the permeation performance of cSMM membranes was interpreted by the solvation of the charged sulfonate groups present in cSMM. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Processing and properties of syntactic foams reinforced with carbon nanotubes
Authors: Guzman Mauricio E. , Rodriguez Alejandro J. , Minaie Bob , Violette Melanie 
Published: October 2011

AbstractThis article presents synthesis and mechanical characterization of carbon nanotube (CNT)‐reinforced syntactic foams. Following a dispersion approach (comprising ultrasonic, calendering, and vacuum centrifugal mixing), single‐ and multi‐walled functionalized CNTs (FCNTs) were incorporated into two foam composites containing various commercially available microballoon grades (S38HS, S60HS, and H50 from 3M). The FCNT‐reinforced composites were tested for compressive strength and apparent shear strength before and after hot/wet conditioning. The results showed that the FCNT‐reinforced composites' mechanical properties depended on the vacuum pressure used during processing. Compared with pristine and commercially available syntactic foam (EC‐3500 from 3M), the FCNT‐reinforced composites processed at high vacuum (0.2 kPa) showed significant increase in compressive strength and apparent shear strength before and after hot/wet conditioning. Dynamic mechanical analysis showed an increase of about 22°C in glass transition temperature for composites processed at high vacuum with 0.5 wt % FCNT and 45 wt % S38HS–5 wt % S60HS microballoons. Thermogravimetric analysis indicated water absorption and lower decomposition temperature for the FCNT‐reinforced composite mixed at atmospheric pressure, whereas no significant change was observed for the compound processed at high vacuum. Fracture analysis showed matrix failure for the composite processed at high vacuum and microballoon crushing for the composite mixed at atmospheric pressure. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
DMA analysis of the damping of ethylene–vinyl acetate/acrylonitrile butadiene rubber blends
Authors: Shi X. Y. , Bi W. N. , Zhao S. G. 
Published: October 2011

AbstractThe mechanical and damping properties of blends of ethylene–vinyl acetate rubber (VA content > 40% wt) (EVM)/acrylonitrile butadiene rubber (NBR), with 1.4 phr BIPB [bis (tert‐butyl peroxy isopropyl) benzene] as curing agent, were investigated by DMA and DSC. The effect of chlorinated polyvinyl chloride (CPVC), silica, carbon black, and phenolic resin (PF) as a substitute curing agent, on the damping and mechanical properties of EVM/NBR blends were studied. The results showed that 10 phr CPVC did not contribute to the damping of EVM700/NBR blends; Silica could dramatically improve the damping of EVM700/NBR blends because of the formation of bound rubber between EVM700/NBR and silica, which appeared as a shoulder tan δ peak between 20 and 70°C proved by DMA and DSC. This shoulder tan δ peak increased as the increase of the content of EVM in EVM/NBR blends. The tensile strength, modulus at 100% and tear strength of the blend with SiO2 increased while the elongation at break and hardness decreased comparing with the blend with CB. PF, partly replacing BIPB as the curing agent, could significantly improve the damping of EVM700/NBR to have an effective damping temperature range of over 100°C and reasonable mechanical properties. Among EVM600, EVM700, and EVM800/NBR/silica blend system, EVM800/NBR/silica blend had the best damping properties. The EVM700/NBR = 80/10 blend had a better damping property than EVM700/NBR = 70/20. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Synthesis of a novel benzoxazine‐containing benzoxazole structure and its high performance thermoset
Authors: Yang Po , Gu Yi 
Published: October 2011

AbstractA novel benzoxazine containing benzoxazole structures (Boz‐BOA) was synthesized and its thermoset [P(Boz‐BOA)] was prepared. For comparison, another benzoxazine‐based 4,4′‐diamine diphenyl methane (Boz‐MDA) was also synthesized using a simplified procedure. The structure of Boz‐BOA and Boz‐MDA was confirmed by Fourier transform infrared (FTIR) and 1H‐NMR. Using FTIR and differential scanning calorimetric scans method, the curing behavior of Boz‐BOA was probed, and the structure of P(Boz‐BOA) was addressed, which was similar to that of P(Boz‐MDA). Data of dynamic mechanical analysis showed that P(Boz‐BOA) exhibited a better modulus retention at high temperature than P(Boz‐MDA), which was attributed to benzoxazole structure restricting the mobility of chains, even at high temperature. P(Boz‐BOA) also exhibited high glass transition temperature (Tg), excellent thermal stability, and low coefficient of thermal expansion value at wide temperature range. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012