bluuebunny/crossref_metadata_2025_split huggingface dataset:
Orbital Schwannomas: Report of Nine Cases and Review of the Literature
Authors: Cantore Giampaolo , Ciappetta Pasquale , Raco Antonino , Lunardi Pierpaolo 
Published: May 2010

Abstract
The authors report 9 cases of orbital schwannoma out of a total of 148 orbital tumors operated. The computed tomography (CT) scan is considered superior to other methods used in the radiological work-up of endoorbital tumors because, in addition to being noninvasive, it gives direct visualization of the lesion and more precise localization both with respect to the muscular cone and tridimensionally. Unfortunately, preoperative diagnosis is not always possible solely on the basis of the CT scan because the enhancement of the tumor is not constant, thus making differential diagnosis with meningioma and cavernous angioma problematic. In addition, CT enables the surgeon to choose the best route for tumor removal. Operative results are good and are influenced by the use of microsurgical techniques.
Postoperative Extradural Hematomas: Computed Tomographic Survey of 1105 Intracranial Operations
Authors: Fukamachi Akira , Koizumi Hidehito , Nagaseki Yoshishige , Nukui Hideaki 
Published: May 2010

Abstract
We reviewed the computed tomographic findings after 1055 intracranial operations to determine the incidence of postoperative extradural hematomas. There were 11 medium and 5 large hematomas after 1055 operations (1.0%). Ten of the 16 hematomas were operated upon (10/1055, 0.9%). Four of the 10 hematomas were seen after 278 brain tumor removals (1.4%), another four after 190 aneurysmal operations (2.1%), one after 14 intracerebral hematoma removals (7.1%), and the last one after 251 ventricular shunting or drainage procedures (0.4%). In 4 of the 10 operated hematomas, sites were regional, in five sites were adjacent, and in one the site was distant. All of the five adjacent hematomas extended downward from a lower rim of the operative locus. Causes were analyzed in the three types of the hematomas. In case of the regional hematomas, the causes were incomplete hemostasis of the dura mater or the bone in all four patients, nonperformance of central stay sutures in three, systemic hypertension in one, and hypofibrinogenemia in one. In the adjacent hematomas, we could find dural separation at an edge of craniotomy in all five patients, abrupt collapse of the brain in all, ventricular dilatation in two, and systemic hypertension during immediate postoperative period in two. In one distant hematoma, ventricular dilatation and ventricular shunting procedure were themselves thought to be the causal factors.
Reactivation of Herpesvirus in Neurosurgical Patients
Authors: Nabors Michael W. , Francis Carolyn K. , Kobrine Arthur I. 
Published: May 2010

Abstract
The authors are presenting seven patients who had operations between July 1984 and July 1985 and who developed herpes infections postoperatively. Four of the patients developed their infections in a dermatomal distribution that correlated with the nerve roots manipulated at operation. A spectrum of localized herpes reactivation is demonstrated in this series. The use of corticosteroids and other associated variables are discussed. Like reactivation of herpes simplex after trigeminal nerve operation, we believe reactivation of herpes simplex and herpes zoster can occur in operation of the cervical, thoracic, or lumbosacral spine.
Carotid Endarterectomy after Recent Stroke: Preliminary Observations in Patients Undergoing Early Operation
Authors: Pritz Michael B. 
Published: May 2010

Abstract
Three patients with recent stroke underwent carotid endarterectomy 1, 4, and 8 days after the onset of maximal symptoms. In each case, computed tomography (CT) demonstrated recent cerebral infarction and cerebral arteriography showed high grade cervical carotid stenosis. No patient developed worsened neurological symptomatology, intracerebral hemorrhage, or vasomotor paralysis. These results suggest that carotid endarterectomy, if indicated, can be performed safely after acute stroke under certain conditions. These criteria include the following: (a) normal level of consciousness, (b) relatively small cerebral infarction without mass effect on CT, and (c) meticulous control and monitoring of systemic blood pressure during the perioperative period. These initial observations suggest that a specific subgroup of patients with recent cerebral infarction may be able safely to undergo carotid endarterectomy shortly after diagnosis.
Impact of Myelography on the Radiotherapeutic Management of Malignant Spinal Cord Compression
Authors: Calkins Alison R. , Olson Margaret A. , Ellis James H. 
Published: May 2010

Abstract
From December 1981 through August 1984, 24 patients with spinal cord compression syndrome due to epidural neoplasms were evaluated for radiotherapy with clinical examination, radiographs of the spine, and myelography. All plain films were reviewed, and mock radiotherapy fields designed using specific criteria for margins. The same patients were reviewed a second time considering the additional information provided by myelography. The initial treatment fields were found to be inadequate in 69% of the patients. Even in patients with discrete bony lesions, the results of myelography affected the treatment 45% of the time. A history of previous spinal irradiation significantly influenced port design in only 1 of the 7 patients who had received previous radiotherapy. Although invasive, myelography is essential in planning the treatment of spinal cord compression.
Symptomatic Progressive Ventriculomegaly in Hydrocephalics with Patent Shunts and Antisiphon Devices
Authors: McCullough David C. 
Published: May 2010

Abstract
The antisiphon device (ASD) was designed to prevent excessive negative intracranial pressure and overdrainage with cerebrospinal fluid shunts. It has been recommended for prevention of slit ventricles and extreme shunt dependency. It was used by the author in 40 children and young adults who had low pressure headaches or were judged to be at risk for the development of subdural hematomas because of extreme hydrocephalus, relatively fixed head size, or tall stature. Nine patients encountered problems with adverse symptoms in spite of shunt patency. Four had alarming neurological symptoms of coma or severe headaches after incorporation of ASDs in ventriculoperitoneal shunt systems. With patients in the horizontal position, shunt patency was documented but computed tomography revealed progressive ventriculomegaly when they were kept erect. Symptoms abated and ventricular size diminished after conversion to proximal medium pressure diaphragm or spring-ball valve systems without ASDs. Because long shunt systems with ASDs require adequate hydrostatic columns to initiate flow when patients are erect, it is theorized that such symptoms could have been prevented by placing ASDs farther downstream from the cerebral ventricles.
Primary Leptomeningeal Glioma Mimicking an Acoustic Neuroma: Case Report with Review of the Literature
Authors: Sceats James D. , Quisling Ronald , Rhoton Albert L. , Ballinger William E. , Ryan Patrick 
Published: May 2010

Abstract
Primary leptomeningeal gliomas are rare. Historically, they have been found in the spinal canal more frequently; however, in the recent literature nearly all have been found within the cranium. In the only cadaveric study of leptomeningeal glial nests, the most frequent site was the medulla and pons. Until now, no leptomeningeal glioma has been found at this site. We report what we believe to be the first such case mimicking an acoustic neuroma.
Functional Recovery after Decompressive Operation for Thoracic and Lumbar Spine Fractures
Authors: Edward C. Benzel , Sanford J. Larson 
Published: May 2010

Abstract
A series of 105 operative cases of thoracic and lumbar spine trauma is presented. All patients underwent an anterior decompression and fusion via the lateral extracavity approach with or without an accompanying posterior internal stabilization procedure (modified Weiss springs or Harrington distraction rods). All patients were allowed to plateau neurologically before reconstructive spine surgery was performed. The patient's neurological grade at the time of surgery and after recovery was assessed according to a seven-grade scale presented herein. None of the 34 patients with a motor and sensory complete myelopathy recovered any function below the level in injury. Of the 10 motor-complete patients with some sensory perception, 4 improved neurologically; however, only 1 of these improved to a state of limited ambulation. The rest remained nonambulatory. Of the 33 patients with significantly disabling incomplete motor and sensory myelopathies, 17 improved to a level of minimal neurological deficit; only 3 patients were left nonambulatory. Of the 21 patients whose physical finding demonstrated a minimal neurological deficit preoperatively, 17 recovered to a normal neurological state. Seven patients were neurologically normal preoperatively and were unchanged postoperatively. Reconstruction of the spine with an anterior decompression and an accompanying stabilization procedure, when appropriate, leads to a better neurological outcome than that expected with either a conservative, nonoperative approach or an operative posterior stabilization approach.
Neurological Deficit after Carotid Infusion of Cisplatin and 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) for Malignant Glioma: An Analysis of Risk Factors
Authors: John P. Kapp , Robert A. Sanford 
Published: May 2010

Abstract
The records of 24 patients with malignant gliomas treated with carotid infusion of cisplatin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) are reviewed for risk factors that might suggest the development of a permanent neurological deficit after infusion. Permanent neurological deficits were seen with doses of cisplatin as low as 69 mg/m2, although doses as high as 100 mg/m2 were tolerated by other patients. All 3 patients who developed permanent neurological deficits received fixed doses of cisplatin of 150 mg and supplied only 2 major intracranial branches from the infused carotid artery. In none of these patients was a filter used in the infusion line. Other risk factors identified in 2 of the 3 patients were diffuse neoplasm involving the region of the internal capsule and the use of an infusion pump rather than a pulsatile bolus infusion technique. The development of a permanent neurological deficit appeared unrelated to the dose of BCNU within the range utilized, and preinfusion administration of corticosteroids did not prevent neurological deficit. These possible risk factors should be considered in the future development of protocols for arterial infusion therapy of malignant gliomas.
Epilepsy after Operation for Aneurysms
Authors: Sbeih I. , Tamas L. B. , O'Laoire S. A. 
Published: May 2010

Abstract
The authors reviewed 100 consecutive survivors of aneurysm operations and identified 3 patients who developed postoperative epilepsy. The use of prophylactic phenytoin in the first 67 cases did not seem to influence the patient's risk of developing epilepsy. It is concluded that with present microneurosurgical techniques the risk of postoperative epilepsy is small and unselective use of phenytoin prophylaxis should be reconsidered.
Spinal Cord Tumors Presenting with Neural Tube Defects
Authors: Gregorios Jocelyn B. , Green Barth , Page Larry , Thomsen Sharon , Monforte Hector 
Published: May 2010

Abstract
Two primary lumbosacral tumors arising at the site of neural tube defects are presented. One was a teratoma diagnosed in an infant with myelomeningocele. The other was an ependymoma that developed in an adult with meningocele. It is postulated that these cases represent a neoplastic transformation of heterotopic primordial elements that have been incorporated within the defect, supporting the view that overgrowth of neural tissue may be the result rather than the cause of neural tube deformity. Such rare occurrences may be due to interaction between intrauterine teratogenic factors and familial predisposition in affected patients.
Aneurysms of the Posterior Cerebral Artery: Report of Ten Cases
Authors: Chang Han Soo , Fukushima Takanori , Takakura Kintomo , Shimizu Tsuneo 
Published: May 2010

Abstract
Ten cases of posterior cerebral artery (PCA) aneurysm are presented. There were 13 aneurysms in the 10 patients: 6 saccular, 5 fusiform, 1 broad-based, and 1 giant fusiform serpentine aneurysm. Eight patients underwent operation: clipping for 2 saccular aneurysms, trapping for 1 saccular and 3 fusiform aneurysms, and coating for 2 fusiform or broad-based aneurysms. Microsurgical cerebral revascularization techniques were attempted in 2 cases: after a fusiform aneurysm had been excised, end-to-end anastomosis of the residual two ends of the PCA was performed and, after a giant serpentine aneurysm had been trapped, the superficial temporal artery was anastomosed transcortically to the distal PCA. Two patients died before operation because of rebleeding and vasospasm. Postoperative neurological deficits include contralateral hemiparesis, homonymous hemianopsia, hemihypesthesia, and ipsilateral 3rd nerve palsy. Our results suggest that, despite the good collateral circulation of the PCA, some ischemic events may occur after trapping procedures and that cerebral revascularization techniques may have some benefit in the treatment of unclippable aneurysms in this region.
Anaplastic Ganglioglioma in an Infant: Case Report and Review of the Literature
Authors: Hall Walter A. , Yunis Eduardo J. , Albright Leland A. 
Published: May 2010

Abstract
A 6-month-old girl had a gradually increasing head circumference. A preoperative computed tomographic (CT) scan of the head revealed an enhancing calcified partially cystic right frontal mass that was removed through a right frontotemporal craniotomy. On microscopic examination, the tumor was composed of sheets of neurons in a glial background alternating with highly cellular anaplastic areas. The diagnosis of anaplastic ganglioglioma was made. The child has done well for the 20 months since the operation without any evidence of tumor recurrence on subsequent CT scans. Because of the immaturity of the child's developing central nervous system, we have elected not to initiate radiotherapy at this time. The pertinent literature regarding gangliogliomas is reviewed.
Unusual Posterior Fossa Dural Arteriovenous Malformation in a Neonate: Case Report
Authors: Ross Donald A. , Walker Joseph , Edwards Michael S. B. 
Published: May 2010

Abstract
We report the case of an infant born with an unusual posterior fossa dural arteriovenous malformation that was supplied by the entire intracranial circulation. The lesion caused hydrocephalus and congestive heart failure that led to the infant's death.
Early Repair of Myelomeningocele and Simultaneous Insertion of Ventriculoperitonal Shunt: Technique and Results
Authors: Hubballah Malek Y. , Hoffman Harold J. 
Published: May 2010

Abstract
During the years 1975 to 1985, 10 patients underwent simultaneous repair of myelomeningocele and insertion of a ventriculoperitoneal shunt at the Hospital for Sick Children in Toronto. The technique for carrying out these procedures in the same operative setting will be described. None of the patients developed shunt infections or myelomeningocele repair breakdown in the follow-up period of 1 to 9 years. One patient died 9 days after operation secondary to aspiration. The remaining patients underwent neuropsychological testing during their follow-up periods and over 70% were found to have normal or slightly below normal intelligence and psychosocial development. The technique of simultaneous repair of a myelomeningocele and insertion of a ventriculoperitoneal shunt in infants with a myelomeningocele and concomitant hydrocephalus overt at birth is safe and should be carried out to decrease the risk of myelomeningocele repair breakdown and cerebrospinal fluid leak in such patients.
Brain Abscess Complicating the Use of a Halo Orthosis
Authors: Goodman Michael L. , Nelson Paul B. 
Published: May 2010

Abstract
We report a case of brain abscess complicating the use of a halo orthosis in the treatment of a cervical spine injury suffered during wrestling. Four previous brain abscesses complicating the use of halo orthoses have been reported. All cases of abscess have been associated with overlying infection at the site of pin insertion. Our case and at least one of those previously reported may have been related to tightening of the halo pins after placement. Serious spine injuries occur rarely in wrestlers and are associated with the use of illegal holds and maneuvers in which one athlete is thrown to the mat. The pathophysiology and radiographic appearance of a unilateral facet dislocation are reviewed.
Intramedullary Melanotic Schwannoma of the Cervicomedullary Junction
Authors: Solomon Robert A. , Handler Michael S. , Sedelli Robert V. , Stein Bennett M. 
Published: May 2010

Abstract
We report a case of a patient with an intramedullary tumor of the cervicomedullary junction. At operation, the tumor was noted to be highly pigmented, and pathological study demonstrated that the tumor was a melanotic schwannoma. Both intramedullary schwannomas and melanotic schwannomas in any location in the body are exceedingly rare. This is the first reported case of an intramedullary melanotic schwannoma of the central nervous system. The possible origin of this tumor is discussed.
Multiple Oncotic Intracranial Aneurysms and Cardiac Metastasis from Choriocarcinoma: Case Report and Review of the Literature
Authors: Seigle J. M. , Caputy Anthony J. , Manz Herbert J. , Wheeler Christine , Fox John L. 
Published: May 2010

Abstract
Ten cases of oncotic intracranial aneurysms from choriocarcinoma have been reported previously. We report an eleventh case with four aneurysms secondary to metastatic choriocarcinoma. These aneurysms seemed to arise from cephalic embolization of neoplastic tissue from an implant of choriocarcinoma in the left ventricle of the heart.
Ectopic Pituitary Gland Simulating a Suprasellar Tumor
Authors: Colohan A. R. T. , Grady M. S. , Bonnin J. M. , Thorner M. O. , Kovacs K. , Jane J. A. 
Published: May 2010

Abstract
A case report of ectopic pituitary gland in the suprasellar region of a normal 39-year-old woman with persistent headaches is presented. The embryological development of the pituitary gland is briefly reviewed, with a discussion of the relevant literature. No previous report of normal pituitary tissue in a suprasellar location in the absence of tumor could be found.
Visual Hallucinations Associated with Pituitary Adenoma
Authors: Ram Zvi , Findler Gideon , Gutman Itzhak , Tadmor Rina , Sahar Abraham 
Published: May 2010

Abstract
Visual hallucinations were the presenting symptom in three patients with pituitary adenoma. One patient reported only simple unformed hallucinations, which are a well-documented phenomenon occurring in lesions compressing the optic nerves and chiasm. The other two patients, however, experienced complex formed visual hallucinations believed to be of the release type. No evidence of seizure activity responsible for the hallucinations was found; the mechanism producing them is discussed with correlation to operative findings and electrophysiological studies.
Isolated Central Nervous System Angiitis First Presenting as Spontaneous Intracranial Hemorrhage
Authors: Biller José , Loftus Christopher M. , Moore Steven A. , Schelper Robert L. , Danks Kelly R. , Cornell Steven H. 
Published: May 2010

Abstract
Two cases of isolated central nervous system angiitis presenting as spontaneous intracranial hemorrhage are reported. The usefulness and limitations of cortical/leptomeningeal biopsy in this condition is described. Emphasis is placed on the clinical awareness of this unusual association to ensure early recognition and prompt management with immunosuppressive therapy.
Transependymal Benign Dorsally Exophytic Brain Stem Gliomas in Childhood: Diagnosis and Treatment Recommendations
Authors: Stroink Ann R. , Hoffman Harold J. , Hendrick Bruce E. , Humphreys Robin P. , Davidson George 
Published: May 2010

Abstract
Sixteen children with dorsally exophytic transependymal benign brain stem gliomas were treated at the Hospital for Sick Children, Toronto, between 1949 and 1985. The diagnosis of these benign brain stem gliomas was based on neuroradiographic and operative observations. Five children were diagnosed in the pre-computed tomography (CT) era using ventriculography and pneumoencephalography, and 11 children were diagnosed using CT with and without contrast enhancement. Histological diagnosis was obtained in all 16 cases. In 1980, we first described this distinct group of benign brain stem gliomas, which accounted for 8% (total, 121 cases) of all brain stem gliomas diagnosed at our institution. However, with the use of high resolution CT in recent years, earlier and better definition of this particular type of brain stem tumor can be made. During the 10 years (1976 to 1985) in which CT has been used for preoperative evaluation in our institution, we have treated 49 patients with primary brain stem tumors. Eleven of these cases (22%) fell into the category of dorsally exophytic transependymal benign brain stem tumors. These tumors characteristically protrude into and largely fill the 4th ventricle, breaking through the overlying ependyma and frequently extending into the cisterna magna. On CT, they are isodense and enhance brightly with contrast agent. Clinically, these patients have a longer history of symptoms in comparison with patients with the more malignant, intrinsic types of brain stem tumor. All of our patients were treated by subtotal resection. Radiotherapy was utilized in 7 of the 16 patients. Periodic CT allowed close follow-up and helped to establish guidelines in the management of these particular patients. Fifteen of the 16 patients are presently alive with follow-up as long as 23 years.
Trigeminal Sensory Evoked Potentials in Patients with Trigeminal Neurinoma: Report of Two Cases
Authors: Takayasu Masakazu , Shibuya Masato , Suzuki Yoshio , Harada Tsutomu , Kanamori Masahiko , Kageyama Naoki 
Published: May 2010

Abstract
The trigeminal sensory evoked potentials (TEPs) in two patients with trigeminal neurinoma are reported. In contrast to the two cases previously reported by others, in which the preoperative TEPs were normal, the two cases reported herein showed significant changes on the affected side: (a) the sensory thresholds were greater and (b) the peak latencies of P19and N28were longer on the affected side than those on the normal side. Our results confirm that a TEP measurement is very useful in a preoperative examination of patients with trigeminal neurinoma, when the function of the trigeminal nerve should be evaluated objectively.
Ossified Prolactinoma: Case Report
Authors: Mukada Kazutoshi , Ohta Masahiro , Uozumi Tohru , Arita Kazunori , Kurisu Kaoru , Inai Kouki 
Published: May 2010

Abstract
The authors report a case of ossified prolactinoma that was identified as a calcified nodule on the roentgenograms. Histologically, the ossified tissues were diffuse, and the osteoid was mineralized in various degress, subsequently forming bones. Adenoma cells were sparse among the ossified tissues. This is probably the first report of ossified pituitary adenoma associated with osteoid metaplasia. The pathogenesis of osteoid metaplasia in pituitary adenomas is possibly due to proliferative connective tissue resulting from degeneration of the pituitary adenoma; this connective tissue may possess osteogenic potency.
Case Report: Myelopathy Secondary to Congenital Osteopetrosis of the Cervical Spine
Authors: McCleary Larry , Rovit Richard L. , Murali Raj 
Published: May 2010

Abstract
A rare occurrence of osteopetrosis involving cervical vertebrae and producing a compressive myleopathy is described. Clinical and radiographic findings are presented, and the pathophysiology of this unusual entity is discussed.