bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does the Market Punish Aggressive Experts? Evidence from Cesarean Sections
Authors: Dranove David , Ramanarayanan Subramaniam , Sfekas Andrew 
Published: May 2011

Abstract
In many credence goods markets, a seller simultaneously diagnoses a problem and offers a recommendation to fix it. One might wonder what prevents these sellers from always exaggerating their customers needs. In this paper, we offer a simple explanation, namely, consumers may spurn sellers who have a reputation for such demand inducement. We test this explanation by examining patient choice of obstetrician in Florida. In most of the counties that we study, we find that maternity patients are significantly less likely to choose obstetricians who perform more than the expected number of cesarean sections. We address simultaneity by instrumenting for inducement propensity using information about the obstetrician's training. Although the instrument is weak, a series of robustness tests suggests that our findings are plausible while ruling out alternative explanations.
Nocturnal Hemodialysis Is Associated with Restoration of Early-Outgrowth Endothelial Progenitor-Like Cell Function
Authors: Yuen Darren A. , Kuliszewski Michael A. , Liao Christine , Rudenko Dmitriy , Leong-Poi Howard , Chan Christopher T. 
Published: May 2011

Summary

Background and objectives
Angiogenesis is a key response to tissue ischemia that may be impaired by uremia. Although early-outgrowth endothelial progenitor-like cells promote angiogenesis in the setting of normal renal function, cells from uremic patients are dysfunctional. When compared with conventional hemodialysis, it was hypothesized that nocturnal hemodialysis would improve the in vivo angiogenic activity of these cells in a well described model of ischemic vascular disease.

Design, setting, participants, and measurements
Early-outgrowth endothelial progenitor-like cells were cultured from healthy controls (n = 5) and age- and gender-matched conventional hemodialysis (12 h/wk, n = 10) and nocturnal hemodialysis (30 to 50 h/wk, n = 9) patients. Cells (5 × 105) or saline were injected into the ischemic hindlimb of athymic nude rats 1 day after left common iliac artery ligation.

Results
Although conventional dialysis cell injection had no effect versus saline, nocturnal hemodialysis and healthy control cell injection significantly improved ischemic hindlimb perfusion and capillary density. Nocturnal hemodialysis cell injection was also associated with significant increases in endogenous angiopoietin 1 expression in the ischemic hindlimb compared with saline and conventional dialysis cell injection.

Conclusions
In contrast to a conventional dialytic regimen, nocturnal hemodialysis is associated with a significantly improved ability of early-outgrowth endothelial progenitor-like cells to promote angiogenesis and thus restore perfusion in a model of ischemic vascular disease.
Changes in proteasome pool in human papillary thyroid carcinoma development
Authors: Sharova Natalia , Astakhova Tatiana , Karpova Yaroslava , Lyupina Yulia , Alekhin Alexander , Goncharov Nikolai , Sumedi Ilia , Cherner Vyacheslav , Rodoman Grigori , Kuznetsov Nikolai , Erokhov Pavel 
Published: May 2011

Abstract
Searching the antitumor drug targets among proteasomes, “ubiquitous” enzyme systems, may provide a new impulse to the antitumor drug discovery. In this study, changes in the proteasome pool in the development of human papillary thyroid carcinoma were determined. Proteasome activities were evaluated by hydrolysis of commercial fluorogenic peptides. Changes in the expression of the total proteasome pool, proteasome 19S activator and proteolytic constitutive subunits X(β5), Y(β1) and immune subunits LMP7 (β5i) and LMP2 (β1i) were investigated by Western blotting. The distribution of the proteasome subunits in thyroid gland cells was detected by immunohistochemistry. It was shown that the chymotrypsin- and caspase-like activities as well as the expression of the total proteasome pool, proteasome 19S activator and immune subunits increased gradually in the tumors at the T2N0M0 and T3N0M0 stages in comparison with the control tissues. Among the structures studied, the expression of the 19S activator and immune proteasomes, which contain the LMP2 (β1i) subunit, was enhanced to the largest degree in tumor cells. The data obtained may be implicated in a new therapeutic strategy. Taking into consideration the antitumor function of the immune proteasomes, we advance the 19S activator as the target for the development of a novel antitumor therapy.
Properties of shrubforest edges: a case study from South Hungary
Authors: Erdős László , Gallé Róbert , Bátori Zoltán , Papp Mónika , Körmöczi László 
Published: May 2011

Abstract
Knowledge on edge properties is important from a conservation perspective. Our study was carried out in the ancient vegetation mosaic of the Villány Mts, South-Hungary. Sampling was conducted along eight transects, each running from a rock sward through a shrubforest patch into another rock sward. Unlike most studies, we identified edge position objectively, using a moving split-window analysis. Five habitat types along each transect were distinguished: north-facing rock sward interior, north-facing edge, shrubforest interior, south-facing edge, and south-facing rock sward interior. In the forty 2 m2 plots, a total of 157 species were found. Species richness and Shannon-diversity of the edges was higher than those of the shrubforest interiors, but not significantly different from the rock swards. Cover did not differ significantly among habitat types. We found only a few edge-related species. No differences between differently-oriented edges were revealed. Species composition of the edges was influenced mostly by the rock sward matrix. We hypothesize that ecological conditions of the edges resemble those of the rock sward interiors. Thus, sward species can penetrate into shrubforest edges, entailing a similar composition of edges and rock swards, resulting in similar diversities. Edges might be viewed as refugia for valuable plants of rock swards.
Laser-Micro/Nanofabricated 3D Polymers for Tissue Engineering Applications
Authors: Danilevičius P. , Žukauskas A. , Bičkauskaitė G. , Purlys V. , Rutkauskas M. , Gertus T. , Paipulas D. , Matukaitė J. , Baltriukienė D. , Malinauskas M. 
Published: May 2011

Laser-Micro/Nanofabricated 3D Polymers for Tissue Engineering ApplicationsA multi-photon polymerization system has been designed based on a pulsed irradiation light source (diode-pumped solid state femtosecond laser Yb:KGW, 300 fs, 1030 nm, 1-200 kHz) in combination with large working area and high precision linear motor driven stages (100×100×50 mm3). The system is intended for high resolution and throughput 3D micro- and nanofabrication and enables manufacturing the polymeric templates up to 1 cm2areas with sub-micrometer resolution. These can be used for producing 3D artificial polymeric scaffolds to be applied for growing cells, specifically, in the tissue engineering. The bio-compatibility of different acrylate, hybrid organic-inorganic and biodegradable polymeric materials is evaluated experimentallyin vitro. Variously sized and shaped polymeric scaffolds of biocompatible photopolymers with intricate 3D geometry were successfully fabricated. Proliferation tests for adult rabbit myogenic stem cells have shown the applicability of artificial scaffolds in biomedicine practice.
Innovation and Regional Socio-Economic Development - Evidence from the Finnish Local Administrative Units (1)
Authors: Makkonen Teemu 
Published: May 2011

Innovation and Regional Socio-Economic Development - Evidence from the Finnish Local Administrative Units (1)It is often argued that innovation plays a key role in the economic growth of regions. Therefore, the impacts of innovation on the socio-economic development of regions have been widely discussed in previous studies, but with divergent areal coverage, methods, and datasets. As a point for departure, these relationships redrawn from international literature are tested here with a single dataset from Finnish local administrative units and with coherent methods. As there does not seem to be a generally accepted indicator for innovation which can claim to be superior, despite the growing literature on the subject, research and development (R&D), and patent statistics are used in this paper to represent innovation activity. The significant, strong, and positive relationship between innovation and traditional socio-economic variables is verified using Finnish regions.
Ageing and Quality of Life - New Responses from the Real Estate Sector in Portugal (1)
Authors: De Matos Fátima 
Published: May 2011

Ageing and Quality of Life - New Responses from the Real Estate Sector in Portugal (1)
In the second half of the 20th century, the history of European demography is associated with a pronounced and widespread process of ageing. The 21st century will have to cater to the needs of an elderly population in transformation. Portugal is also part of this process and in efforts to improve the quality of life of the elderly, a wide range of facilities, services and social responses have been established by a variety of promoters, targeting several social levels. This paper will analyze a specific segment directed at an exclusive niche of the elderly population, the Senior Residential Condominiums. This is a very recent segment of the housing market, with high levels of comfort, quality, sanitation, health, and recreation, essential to full well-being. The paper intends to characterize this real estate market niche so as to identify its distinctive features, the promoting agents and how they can contribute to residents' quality of life.
Film Festivals in Łódź as a Main Component of Urban Cultural Tourism
Authors: Cudny Waldemar 
Published: May 2011

Film Festivals in Łódź as a Main Component of Urban Cultural TourismIn the early 19thcentury Łódź became a huge centre of textile production. However, the transformations in Poland after 1989 led to the decline of this industry. At present the city is looking for new forms of development, such as services, including tourism and culture. One of the most important elements of the cultural function in Łódź are film festivals, based on over 50 year long tradition of film making in this city. The aim of this article is to present the film festivals organized in Łódź, which are a tourist asset and a kind of tourist product (an event). They are at the same time an element of cultural tourism, part of which is event tourism, connected with festivals and film tourism.
The Conversions of the City Structure and their Influence on the Demographic Phenomena
Authors: Chądzyńska Elżbieta 
Published: May 2011

The Conversions of the City Structure and their Influence on the Demographic Phenomena
The process of socio-economic change, which started in Poland in 1989, began the series of modifications in the structure of Polish cities. These changes embrace the economic sphere and the social sphere, as well as the habitable environment. The changes occurring in Polish cities resemble the processes present in settlement systems in highly developed countries. They take place, however, with some delay which is caused by the movement from the centrally controlled economy to the market economy and all the problems associated with it.The aim of the presented article is to show the influence of occurring changes on the socio-economic development and demographic situation apparent in small towns of the Wrocław Metropolitan Area (WrMA). The attempt of evaluation of factors promoting the development was undertaken. The value of chosen characteristics was analyzed for the set of small towns of Dolnośląskie voivodship. The analysis of chosen quantities common for demographic phenomena in a longer time cross-section (1995-2008) pinpoints the irregularity of development of specific towns, which may result in negative effects for the whole area in the future.
Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits
Authors: Kale Aydemir , Börcek Alp Özgün , Emmez Hakan , Yildirim Zuhal , Durdağ Emre , Lortlar Neşe , Kurt Gökhan , Doğulu Fikret , Kılıç Nedret 
Published: May 2011

ObjectExtensive research has been focused on neuroprotection after spinal cord trauma to alleviate the effects of secondary injury. This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury.MethodsThirty-two adult male New Zealand white rabbits received spinal cord ischemic injury using the aortic occlusion model. Animals were divided into 4 groups (sham, control, low-dose, and high-dose treatment groups; 8 rabbits in each group). High (200 mg/kg) and low (30 mg/kg) doses of gabapentin were administered to the animals in the treatment groups after spinal cord ischemic injury. Neurological status of the animals, ultrastructural findings in injured tissue samples, and levels of tissue injury markers in these 2 groups were compared with findings in the animals that did not receive the ischemic procedure (sham-operated group) and those that received normal saline after administration of ischemia.ResultsRegarding levels of tissue injury marker levels after ischemic injury, animals in the gabapentin-treated groups demonstrated better results than animals in the other groups. The ultrastructural findings and caspase-3 activity were similar. The treatment groups demonstrated better results than the other groups.ConclusionsGabapentin demonstrated significant neuroprotection after early phases of ischemic injury. Further studies with different experimental settings including neurological outcome are required to achieve conclusive results.
Medial radio-carpal arthrodesis in three cats with a 2.0 mm locking maxillofacial plate system
Authors: Makara M. , Guerrero T. , Streubel R. 
Published: May 2011

SummaryThe medical records of three cats that were presented with severe carpal injury requiring radiocarpal arthrodesis were reviewed. Medial plating using the Compact 2.0 LOCKTM system a was performed in all three cases. Although screw positioning may be difficult because of the large distance between the holes of the plate and the relatively large size of screws, plate loosening or metacarpal fractures did not occur. Long-term clinical and radiographic follow-up (6 months to 4.5 years) revealed excellent outcome in two cats. In the third cat, the radiocarpal joint did not undergo complete fusion. At four and a half years following surgery, recurrence of forelimb lameness was associated with breakage of the plate.
Perceived Value of National Certification for Pediatric Nurses
Authors: Messmer Patricia R. , Hill-Rodriguez Deborah , Williams Arthur R. , Ernst Mary E. , Tahmooressi Jill 
Published: May 2011

Purpose:
This study evaluated whether pediatric nurses who were certified valued national certifications to a greater degree than those who were not certified.

Methods:

The Gaberson, Schroeter, Killen, and Valentine (
2003
) Perceived Value of Certification Tool (PVCT) was used to measure nurses’ perceptions of certification. The PVCT includes 18 certification-related value statements, using a five-point Likert scale response ranging from strongly agree to strongly disagree. A principal factor analysis was performed to identify clusters of related variables.

Results:
Certified pediatric nurses valued national certifications to a greater degree than those who were not certified. More favorable views of certification were moderately associated with favorable views of the effects of certification on salary. The PVCT was found to have one factor, not two, as previously reported in the literature. Lower perceived relationships were reported between certification and salary, clinical competence, and consumer confidence compared with feelings of professionalism and personal satisfaction.

Conclusion:
Efforts to improve the relationship between certification and its perceived value at one institution were addressed. More attention may be needed to strengthen relationships, perceived or otherwise, between certification and competency skills, public awareness, and compensation of nurses for holding national certification.
The Connection Between Strong Social Support and Joint Replacement Outcomes
Authors: Theiss Mark M. , Ellison Michael W. , Tea Christine G. , Warner Julia F. , Silver Renee M. , Murphy Valerie J. 
Published: May 2011

A myriad of emotional, informational, and tangible needs can easily overwhelm patients as they seek to navigate a complicated surgical procedure. This article demonstrates that a dedicated family member or friend supporting their loved one before, during, and after joint replacement surgery measurably impacts quality and outcomes. The multidisciplinary, multihospital study team developed the following Opportunity Statement: “To define, measure, and implement a progressive family/friend support system across the continuum of care promoting optimal patient recovery after total joint arthroplasty.” The team used the modified Groningen Orthopedic Social Support Scale to measure levels of social support and associated these levels with other patient outcomes.
Analysis of 1722 observations across 4 hospitals found that patients with strong social support have shorter hospital stays, are more likely to be discharged home, to meet ambulation and transfer-out-of-bed targets, and to score hospital quality of care higher, and are more confident and ready to go home on discharge. Three presence intervals were also found to be significant predictors of key outcome measures: family/friend presence during the preoperative classes, in the preoperative holding area, and during the last physical therapy session. These intervals may serve as reasonable social support proxies for organizations desiring to measure social support to ultimately affect quality and outcomes.
Clinical Features and Treatment of the Hip in Multiple Epiphyseal Dysplasia in Childhood
Authors: Li Lian Yong , Zhao Qun , Ji Shi Jun , Zhang Li Jun , Li Qi Wei 
Published: May 2011

Multiple epiphyseal dysplasia is a rare congenital osteochondrodysplasia disorder characterized by a delay in the appearance of the epiphyses; irregular, symmetric epiphyseal formation; mild short stature; and early-onset osteoarthritis. Peripheral weight-bearing and nonweight-bearing joints can be affected. Treatment of the hip deformity in multiple epiphyseal dysplasia is a challenge for orthopedic surgeons.
We reviewed the clinical features and treatment options of hip joints affected by multiple epiphyseal dysplasia in 6 young patients (4 boys and 2 girls). Average patient age was 8.8 years (range, 5–14 years). The spectrum of hip joint deformity ranged from mild to severe. Surgical procedures included intertrochanteric extension osteotomy of the femur in 2 patients (4 hips), Staheli acetabular augmentation in 1 patient (2 hips), and trochanter arthroplasty associated with Dega osteotomy in 2 patients (4 hips). One patient did not undergo surgical treatment. All patients were followed up for an average 7.2 years. Joint function improved in the patients treated surgically. The coxa vara deformity was corrected satisfactorily, and the femoral head was covered completely by the acetabulum.
Good mid-term outcomes were obtained for the treatment of severe hip deformity by using intertrochanteric extension osteotomy and trochanter arthroplasty. However, because of the inherent nature of this disorder, long-term follow-up of the patients is required.
Trends in Femoroacetabular Impingement Research over 11 Years
Authors: Haviv Barak , Burg Alon , Velkes Steven , Salai Moshe , Dudkiewicz Israel 
Published: May 2011

Femoroacetabular impingement is the abutment between the proximal femur and the rim of the acetabulum. It is a common cause of labral injury that has been identified as an early cause of hip osteoarthritis. The diagnosis of femoroacetabular impingement of the hip is currently well defined in orthopedic surgery but should attract the attention of physicians in other disciplines. Conversely, much less is known about the etiology and natural history of femoroacetabular impingement.
The goal of this study was to assess the number of articles published on femoroacetabular impingement over 11 years in orthopedic vs nonorthopedic medical journals, and to evaluate the quality of available evidence. PubMed and OvidSP databases were searched for articles on femoroacetabular impingement published from 1999 to 2009. Articles were characterized by publication type and journal type per year. Regression analysis was used to determine the effect of publication year on number of publications of each type. The search yielded 206 publications on femoroacetabular impingement during the evaluation period. Seventy-two percent were published in orthopedic journals. Overall, the number of publications increased exponentially with time. There was an increase in clinical trials over the course of the study period. However, studies with high-quality evidence were scarce. The increase in data from orthopedic and nonorthopedic disciplines is welcome. Nevertheless, high-quality evidence on femoroacetabular impingement is lacking. We believe the current trend toward evidence-based orthopedic surgery will impact future research on this relatively new disorder.
Short-Term Outcome of Bilateral Decompression via a Unilateral Paramedian Approach for Transforaminal Lumbar Interbody Fusion with Unilateral Pedicle Screw Fixation
Authors: Feng Zhen-Zhou , Cao Yuan-Wu , Jiang Chun , Jiang Xiao-Xing 
Published: May 2011

The purpose of this study was to evaluate the clinical and radiologic outcomes of bilateral decompression via a unilateral paramedian approach for transforaminal lumbar interbody fusion. Forty consecutive patients satisfying the inclusion criteria were divided randomly into groups 1 and 2. Patients were treated with unilateral (group 1) or bilateral (group 2) pedicle screw fixation and bilateral decompression via 1-sided (group 1) or bilateral (group 2) paramedian approach. Perioperative parameters (operation time, blood loss, hospital stay, complications, and implant cost), clinical outcome parameters (Japanese Orthopedic Association [JOA] scores, visual analog scale [VAS] scores, and Oswestry Disability Index [ODI] preoperatively and at 1 week and 3 months postoperatively), and radiologic parameters (radiograph and computed tomography [CT] scan preoperatively and at 1 week postoperatively) were compared.
No differences were seen between groups 1 and 2 with respect to operation time, blood loss, or hospital stay. No complications were observed in either group. The ODI, JOA, and VAS values of both groups showed significant differences between the preoperative and 1-week or 3-month postoperative values. No significant differences were seen in the improvements of the ODI, JOA, and VAPS values between groups 1 and 2 at any postoperative time point. Postoperative CT indicated that the contralateral decompression was sufficient in both groups.
The short-term results indicate that bilateral decompression via a unilateral paramedian approach for transforaminal lumbar interbody fusion with unilateral pedicle screw fixation is safe, feasible, and effective over the short-term and is more cost-efficient than a bilateral paramedian approach.