bluuebunny/crossref_metadata_2025_split huggingface dataset:
Host‐mediated induction of α‐amylases by larvae of the Mexican bean weevil Zabrotes subfasciatus (Coleoptera: Chrysomelidae: Bruchinae) is irreversible and observed from the initiation of the feeding period
Authors: Bifano Thaís D. , Samuels Richard I. , Alexandre Daniel , Silva Carlos P. 
Published: July 2010

AbstractLarvae of Zabrotes subfasciatus secrete α‐amylases that are insensitive to the α‐amylase inhibitor found in seeds of Phaseolus vulgaris. By analyzing amylase activities during larval development on P. vulgaris, we detected activity of the constitutive amylase and the two inducible amylase isoforms at all stages. When larvae were transferred from the non α‐amylase inhibitor containing seeds of Vigna unguiculata to P. vulgaris, the inducible α‐amylases were expressed at the same level as in control larvae fed on P. vulgaris. Interestingly, when larvae were transferred from seeds of P. vulgaris to those of V. unguiculata, inducible α‐amylases continued to be expressed at a level similar to that found in control larvae fed P. vulgaris continuously. When 10‐day‐old larvae were removed from seeds of V. unguiculata and transferred into capsules containing flour of P. vulgaris cotyledons, and thus maintained until completing 17 days (age when the larvae stopped feeding), we could detect higher activity of the inducible α‐amylases. However, when larvae of the same age were transferred from P. vulgaris into capsules containing flour of V. unguiculata, the inducible α‐amylases remained up‐regulated. These results suggest that the larvae of Z. subfasciatus have the ability to induce insensitive amylases early in their development. A short period of feeding on P. vulgaris cotyledon flour was sufficient to irreversibly induce the inducible α‐amylase isoforms. Incubations of brush border membrane vesicles with the α‐amylase inhibitor 1 from P. vulgaris suggest that the inhibitor is recognized by putative receptors found in the midgut microvillar membranes. © 2010 Wiley Periodicals, Inc.
A comparative study of Flickr tags and index terms in a general image collection
Authors: Rorissa Abebe 
Published: July 2010

AbstractWeb 2.0 and social/collaborative tagging have altered the traditional roles of indexer and user. Traditional indexing tools and systems assume the top‐down approach to indexing in which a trained professional is responsible for assigning index terms to information sources with a potential user in mind. However, in today's Web, end users create, organize, index, and search for images and other information sources through social tagging and other collaborative activities. One of the impediments to user‐centered indexing had been the cost of soliciting user‐generated index terms or tags. Social tagging of images such as those on Flickr, an online photo management and sharing application, presents an opportunity that can be seized by designers of indexing tools and systems to bridge the semantic gap between indexer terms and user vocabularies. Empirical research on the differences and similarities between user‐generated tags and index terms based on controlled vocabularies has the potential to inform future design of image indexing tools and systems. Toward this end, a random sample of Flickr images and the tags assigned to them were content analyzed and compared with another sample of index terms from a general image collection using established frameworks for image attributes and contents. The results show that there is a fundamental difference between the types of tags and types of index terms used. In light of this, implications for research into and design of user‐centered image indexing tools and systems are discussed.
Chemiluminescence sensor for sulfonylurea herbicide using molecular imprinted microspheres as recognition element
Authors: Xie Cheng‐gen , Gao Shan , Zhou Han‐kun , Li Huai‐fen 
Published: July 2010

AbstractUniform molecular imprinting microspheres were prepared using precipitation polymerization with thifensulfuron‐methyl (TFM) as template, acrylamide as functional monomer and ethylene glycol dimethacrylate as cross‐linker. TFM could be selectively adsorbed on the molecularly imprinted polymers (MIPs) matrix through the hydrogen bonding interaction and the adsorbed TFM could be sensed by its strikingly enhancing effect on the weak chemiluminescence (CL) reaction between luminol and hydrogen peroxide. On this basis, a novel CL sensor for the determination of TFM using MIPs as recognition elements was established. The logarithm of net CL intensity (ΔI) is linearly proportional to the logarithm of TFM concentration (C) in the range from 1.0 × 10−9 to 5.0 × 10−5 mol L−1 with a detection limit of 8.3 × 10−10 mol L−1 (3σ). The results demonstrated that the MIP–CL sensor was reversible and reusable and that it could strikingly improve the selectivity and sensitivity of CL analysis. Furthermore, it is suggested that the CL enhancement of luminol–H2O2 by TFM might be ascribed to the enhancement effect of CO2, which came from TFM hydrolysis in basic medium. Copyright © 2010 John Wiley & Sons, Ltd.
Enhanced chemiluminescence of peroxomonosulfate–cobalt (II) system in the presence of dicarboxylic acids
Authors: Zhou Yun , Ogawa Nobuaki , Lin Jin‐Ming 
Published: July 2010

AbstractIn the present work, the effects of molecular mass aliphatic dicarboxylic acids on the HSO5‐–Co2+ chemiluminescence (CL) system were investigated. It was found that the aliphatic dicarboxylic acids could enhance the CL of the HSO5‐–Co2+ system. Moreover, the CL intensities improved regularly with increasing carbon chain length of the dicarboxylic acids. To investigate the CL enhancement mechanism, dynamic profiles, CL spectroscopy, ESR spectrum and the effects of various free radical scavengers on the CL system were employed. The results indicated that the enhancement of the CL should be attributed to the formation of peroxo‐diacid, which finally decomposed to the original dicarboxylic acid and singlet oxygen. The mechanism of the HSO5‐–Co2+‐dicarboxylic acid CL system was then proposed. Copyright © 2010 John Wiley & Sons, Ltd. Copyright © 2010 John Wiley & Sons, Ltd.
Cu2+‐imprinted cross‐linked chitosan resin as micro‐column packing materials for online chemiluminescence determination of trace copper
Authors: Nie Feng , Hao Liang , Gao Mei , Wu Yingchun , Li Xinsheng , Yu Sha 
Published: July 2010

AbstractThe Cu2+‐imprinted cross‐linked chitosan resin was synthesized and the binding characteristic of the resin to Cu2+ was evaluated. The prepared resin was packed into a micro‐glass column and used as micro‐separating column. The micro‐separating column was connected into the chemiluminescence flow system and placed in front of the window of the photomultiplier tube. Based on the luminol–hydrogen peroxide chemiluminescence system, a flow injection online chemiluminescence method for determination of trace copper was developed and trace Cu2+ in complex samples was successfully determined. The proposed method improved the shortcomings of chemiluminescence method's poor selectivity. Copyright © 2010 John Wiley & Sons, Ltd.
Synergistic action of oncolytic herpes simplex virus and radiotherapy in pancreatic cancer cell lines
Authors: Dai M-H , Zamarin D , Gao S P , Chou T-C , Gonzalez L , Lin S-F , Fong Y 
Published: July 2010

AbstractBackgroundDespite much research in chemotherapy and radiotherapy, pancreatic adenocarcinoma remains a fatal disease, highly resistant to all treatment modalities. Recent developments in the field of herpes simplex virus (HSV) engineering have allowed the generation of a number of promising virus vectors for treatment of many cancers, including pancreatic tumours. This study examined the use of one such virus, NV1023, in combination with radiation therapy in pancreatic cancer cell lines.MethodsHSV therapy in combination with radiotherapy was investigated in pancreatic cancer cell lines Hs766T, Panc-1 and MIA PaCa-2. Multiple therapy effect analysis was performed by computerized simulation. Mechanisms underlying synergy, such as virus replication and apoptosis, were investigated.ResultsThe combination of NV1023 and radiation yielded a synergistic oncolytic effect in all tested pancreatic cancer cell lines, with the greatest effect achieved in MIA PaCa-2. This effect was not mediated by an increase in rapid viral replication, but by a substantial increase in apoptosis.ConclusionThe synergistic oncolytic actions of HSV and radiotherapy observed in pancreatic cancer cell lines encourage further testing of this multimodality treatment.
Randomized double-blind placebo-controlled crossover study of caffeine in patients with intermittent claudication
Authors: Momsen A H , Jensen M B , Norager C B , Madsen M R , Vestersgaard-Andersen T , Lindholt J S 
Published: July 2010

Abstract

Background
Intermittent claudication is a disabling symptom of peripheral arterial disease for which few medical treatments are available. This study investigated the effect of caffeine on physical capacity in patients with intermittent claudication.

Methods
This randomized double-blind placebo-controlled crossover study included 88 patients recruited by surgeons from outpatient clinics. The participants abstained from caffeine for 48 h before each test and then received either a placebo or oral caffeine (6 mg/kg). After 75 min, pain-free and maximal walking distance on a treadmill, perceived pain, reaction times, postural stability, maximal isometric knee extension strength, submaximal knee extension endurance and cognitive function were measured. The analysis was by intention to treat.

Results
Caffeine increased the pain-free walking distance by 20·0 (95 per cent confidence interval 3·7 to 38·8) per cent (P = 0·014), maximal walking distance by 26·6 (12·1 to 43·0) per cent (P &lt; 0·001), muscle strength by 9·8 (3·0 to 17·0) per cent (P = 0·005) and endurance by 21·4 (1·2 to 45·7) per cent (P = 0·004). However, postural stability was reduced significantly, by 22·1 (11·7 to 33·4) per cent with eyes open (P &lt; 0·001) and by 21·8 (7·6 to 37·8) per cent with eyes closed (P = 0·002). Neither reaction time nor cognition was affected.

Conclusion
In patients with moderate intermittent claudication, caffeine increased walking distance, maximal strength and endurance, but affected balance adversely. Registration number: NCT00388128 (http://www.clinicaltrials.gov).
Surgery for multiple endocrine neoplasia type 1-associated primary hyperparathyroidism
Authors: Waldmann J , López C L , Langer P , Rothmund M , Bartsch D K 
Published: July 2010

Abstract

Background
Surgery in patients with multiple endocrine neoplasia type 1 (MEN1)-associated primary hyperparathyroidism (pHPT) is difficult as the condition it is caused by asymmetrical multiple gland hyperplasia. It is uncertain which operative procedure provides the best outcome with regard to long-term normocalcaemia.

Methods
All patients who had surgery for genetically confirmed MEN1-associated pHPT between 1987 and 2009 were identified from a prospective database. Clinical data, operative procedures and outcome were analysed retrospectively.

Results
A total of 47 patients were identified. Twenty-three patients underwent total parathyroidectomy with thymectomy and autotransplantation (TPTX + AT), 11 patients subtotal parathyroidectomy (3–3·5 glands, SPTX) with thymectomy, and 13 patients selective gland excision (fewer than 3 glands, SGE). Rates of persistent disease, recurrent disease and permanent hypoparathyroidism after TPTX + AT were 4 per cent (1 patient), 4 per cent (1 patient) and 22 per cent (5 patients) respectively. Respective rates after SPTX were 0 per cent, 18 per cent (2 patients) and 45 per cent (5 patients), which were not statistically different from those following TPTX + AT. SGE resulted in persistent disease in 23 per cent (3 patients) and a significantly higher rate of recurrent disease (46 per cent, 6 patients; P = 0·004 versus TPTX, P = 0·210 versus SPTX), but permanent hypoparathyroidism did not occur.

Conclusion
TPTX + AT and SPTX both seem adequate surgical procedures for the treatment of MEN1-associated pHPT and are associated with fewer recurrences than SGE.
Sphincter preservation in rectal cancer is associated with patients' socioeconomic status
Authors: Olsson L I , Granström F , Påhlman L 
Published: July 2010

Abstract

Background
Decision making regarding the choice of surgical procedure in rectal cancer is complex. It was hypothesized that, in addition to clinical factors, several aspects of patients' socioeconomic background influence this process.

Methods
Individually attained data on civil status, education and income were linked to the Swedish Rectal Cancer Registry 1995–2005 (16 713 patients) and analysed by logistic regression.

Results
Anterior resection (AR) was performed in 7433 patients (44·5 per cent), abdominoperineal resection (APR) in 3808 (22·8 per cent) and Hartmann's procedure in 1704 (10·2 per cent). Unmarried patients were least likely (odds ratio (OR) 0·76, 95 per cent confidence interval (c.i.) 0·64 to 0·88) and university-educated men were most likely (OR 1·30, 1·04 to 1·62) to have an AR. Patients with the highest income were more likely to undergo AR (OR 0·80, 0·85 and 0·86 respectively for first, second and third income quartiles). Socioeconomic differences in the use of AR were smallest among the youngest patients. Unmarried patients were more likely (OR 1·21, 95 per cent c.i. 1·00 to 1·48) and university-educated patients less likely (OR 0·78, 95 per cent c.i. 0·63 to 0·98) to have an APR.

Conclusion
The choice of surgical strategy in rectal cancer is not socioeconomically neutral. Confounding factors, such as co-morbidity or smoking, may explain some of the differences but inequality in treatment is also plausible.
Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer
Authors: Jayne D G , Thorpe H C , Copeland J , Quirke P , Brown J M , Guillou P J 
Published: July 2010

Abstract

Introduction
The UK Medical Research Council CLASICC trial assessed the safety and efficacy of laparoscopically assisted surgery in comparison with open surgery for colorectal cancer. The results of the 5-year follow-up analysis are presented.

Methods
Five-year outcomes were analysed and included overall and disease-free survival, and local, distant and wound/port-site recurrences. Two exploratory analyses were performed to evaluate the effect of age (70 years or less, or more than 70 years) on overall survival between the two groups, and the effect of the learning curve.

Results
No differences were found between laparoscopically assisted and open surgery in terms of overall survival, disease-free survival, and local and distant recurrence. Wound/port-site recurrence rates in the laparoscopic arm remained stable at 2·4 per cent. Conversion to open operation was associated with significantly worse overall but not disease-free survival, which was most marked in the early follow-up period. The effect of surgery did not differ between the age groups, and surgical experience did not impact on the 5-year results.

Conclusion
The 5-year analyses confirm the oncological safety of laparoscopic surgery for both colonic and rectal cancer. The use of laparoscopic surgery to maximize short-term outcomes does not compromise the long-term oncological results. Registration number: ISRCTN74883561 (http://www.controlled-trials.com).
Study of chromatographic characteristics of inorganic analytes in biopartitioning micellar chromatography with ion‐pair additives
Authors: Rukhadze Marina , Lominadze Nino , Akhalkatsi Levan , Gvaramia Manuchar 
Published: July 2010

AbstractThe chromatographic behavior of model ions of biomedical and environmental significance was investigated by using nonionic micellar mobile phases modified with ion‐pair additives. The influence of concentrations of polyoxyethylene (23) lauryl ether and ornithine hydrochloride in the mobile phase on the retention factors of chromium (III), chromium (VI), iodide and bromide ions was studied. The possible mechanisms of retention of the mentioned ions in biopartitioning micellar chromatography with zwitter ion‐pair additives were proposed. Copyright © 2010 John Wiley & Sons, Ltd.
SR‐BI, CD36, and caveolin‐1 contribute positively to cholesterol efflux in hepatic cells
Authors: Truong To Quyen , Aubin Dominique , Falstrault Louise , Brodeur Mathieu R. , Brissette Louise 
Published: July 2010

AbstractIn non‐hepatic cells, scavenger receptor class B type I (SR‐BI), cluster of differentiation 36 (CD36), and caveolin‐1 were described as mediators of cholesterol efflux, the first step of reverse cholesterol transport (RCT). Stable transformants of HepG2 cells overexpressing SR‐BI, CD36, or caveolin‐1 were generated, as well as cells overexpressing both caveolin‐1 and SR‐BI or caveolin‐1 and CD36 in order to address the effect of caveolin‐1 on both receptor activities. These cells were analyzed for their ability to efflux cholesterol to HDL3. Our results show that overexpressing SR‐BI, CD36, or caveolin‐1 increases cholesterol efflux by 106, 92, and 48%, respectively. Moreover, the dual overexpressions of caveolin‐1 and SR‐BI or caveolin‐1 and CD36 lead to a more prominent increase in cholesterol efflux. Studies were also conducted with primary cultures of SR‐BI knockout (KO), CD36 KO, and SR‐BI/CD36 double‐KO (dKO) mice. SR‐BI KO and SR‐BI/CD36 dKO hepatic cells show 41 and 56% less cholesterol efflux, respectively, than normal hepatic cells. No significant difference was observed between the efflux of normal and CD36 KO cells. The difference between the role of human and murine CD36 correlated with the absence of CD36 dimers in mouse caveolae/rafts. Overall, our results show that SR‐BI is clearly involved in cholesterol efflux in mouse and human hepatic cells, while CD36 plays a significant role in human cells. Copyright © 2010 John Wiley & Sons, Ltd.
Influence of Filter Cloth Behavior on the Layout of Cake Forming Filters
Authors: Ehrfeld E. 
Published: July 2010

AbstractIn order to determine the exact influence of filter cloth behavior on the layout of cake forming filters, it is a requirement to carry out laboratory tests in an exact manner. Even if the separation characteristics of solid/liquid mixtures (suspensions) can be described theoretically, the most important parameters of the solid/liquid separation technique must still be determined by carrying out laboratory or field tests. In particular, the influence of the filter cloth on the filtration behavior has to be determined by means of test work with the respective suspension and with an appropriate laboratory test device. A method is described to determine the filter cloth resistance by lab‐scale tests under conditions close to reality. The test results are compared to typical characterization cloth data provided by manufacturers.
ChemInform Abstract: Novel Lanthanoid—Cadmium Oxide Pnictides with the Tetragonal LaOAgS Structure.
Authors: Charkin D. O. , Berdonosov P. S. , Dolgikh V. A. , Lightfoot P. 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Trisaccharide Glycolipid Biosurfactant Containing Trehalose Bears Ester‐Linked Hexanoate, Succinate, and Acyloxyacyl Moieties: NMR and MS Characterization of the Underivatized Structure.
Authors: Esch Steven Wynn , Morton Martha D. , Williams Todd D. , Buller Clarence S. 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of (R)‐ and (S)‐4‐Methoxydalbergione via Asymmetric Catalytic Hydrogenation.
Authors: Bissel Philippe , Nazih Abdesslame , Sablong Rafael , Lepoittevin Jean‐Pierre 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of C‐Glycosylangucycline, Urdamycinone B, Using an Unprotected Sugar.
Authors: Matsuo Goh , Miki Yuko , Nakata Masaya , Matsumura Shuichi , Toshima Kazunobu 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convergent Synthesis of (+)‐Muconin
Authors: Yang Wen‐Qian , Kitahara Takeshi 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Total Synthesis of Avarol and Avarone.
Authors: Ling Taotao , Xiang Alan X. , Theodorakis Emmanuel A. 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Synthesis of 12‐epi‐PGF2α and 12,15‐diepi‐PGF2α.
Authors: Lai Sheng , Lee Dongreyoul , U Jong Sun , Cha Jin Kun 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Oriented Ba2NaNb5O15 (BNN) Thin Films from an Alkoxy‐Derived Precursor.
Authors: Yogo Toshinobu , Sakamoto Wataru , Isaji Tadayuki , Ichida Masao , Nakamura Arao , Hirano Shin‐ichi 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Deposition of Multifunctional Titania Ceramic Films by Aerosol Routes.
Authors: Yang Guixiang , Biswas Pratim , Boolchand Punit , Sabata Ashok 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnesium Insertion Electrodes for Rechargeable Nonaqueous Batteries — A Competitive Alternative to Lithium?
Authors: Noval Petr , Imhof Roman , Haas Otto 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.