bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rentabilidad de la inversión en capital humano y discrepancias salariales por género en el municipio de Villavicencio (Colombia) entre los años 2008 y 2020
Authors: Fuentes Rodriguez Germán , Bejarano Rodríguez Yeisson , Castellanos Linares César  Augusto 
Published: May 2024

Históricamente la desigualdad de género se ha manifestado de diferentes formas en diferentes regiones del mundo, y esta discrepancia ha suscitado una serie de apreciaciones respecto del crecimiento económico, y su relación con la rentabilidad de la inversión en capital humano, ya que tradicionalmente el nivel educativo de una persona incrementa su capacidad productiva y por ende su remuneración; es por esto que el nivel educativo y cultural que tenga la población de un país es uno de los determinantes principales de su desarrollo social y económico. Sin embargo, es importante resaltar que resultados de investigaciones sobre este tema, muestran como la desigualdad educativa puede afectar el crecimiento, pero no indican que el hecho de que las mujeres inviertan en educación, les garantice mejores ingresos u oportunidades laborales. Por esto, la finalidad del presente análisis del retorno de la inversión en educación se abordó desde una perspectiva de la competitividad, teniendo en cuenta que los avances en formación y en experiencia representan una significativa incidencia sobre los resultados productivos del factor trabajo, así como las discrepancias salariales por género.
Para tal fin se desarrolló un modelo econométrico de tipo Minceriano estimado a través del método de Mínimos Cuadrados Ordinarios (MCO); que mediante un análisis de corte transversal permitió cuantificar la TIR de la educación y la incidencia que tiene la acumulación de capital humano a través del incremento en los niveles educativos, sobre las mejoras salariales de los individuos; con el fin de describir el comportamiento de esta variable en Villavicencio y así analizar su tendencia durante los años en estudio y la diferenciación salarial entre si es hombre o mujer
PEMBERDAYAAN KELOMPOK TANI MELALUI PEMANFAATAN LIGHT TRAP BERBASIS ENERGI SURYA PADA LAHAN SAWAH UNTUK MENGURANGI PENGGUNAAN PESTISIDA
Authors: AR Trisnawaty , Thamrin Nining Triani , Sofyan Wahyudi , Asra Reza , Mursalat Aksal , Irwan Muh. 
Published: May 2024

Penggunaan light trap sebagai upaya mengurangi penggunaan pestisida sintetik dalam pengendalian hama yang ramah lingkungan merupakan usaha altematif yang lebih efektif dalam mengendalikan populasi dan penyebaran serangga hama. Kegiatan ini bertujuan untuk memberikan pendampingan dan pembinaan secara berkala kepada kelompok tani Desa Carawali terkait pengaplikasian light trap di lapangan. Kegiatan Pengabdian pada masyarakat ini meliputi dilaksanakan pada bulan Januari – Maret 2023 di desa Carawali, Kec. Watang Pulu, Kabupaten Sidenreng Rappang. Kegiatan meliputi: a.) Obeservasi dan survei lokasi; b) Sosialisasi; c) Pelaksanaan pendampingan; d) Pengamatan, serta e) Monitoring dan Evaluasi. Hasil pengamatan tangkapan alat perangkap hama light trap berbasis energi surya yang telah dipasang pada lahan sawah petani memperlihatkan hasil tangkapan yang cukup banyak dan setelah minggu ke-4 populasi hama serangga di areal penanaman padi makin berkurang. pemanfaatan light trap berbasis energi surya merupakan solusi yang efektif untuk mengurangi penggunaan pestisida pada lahan sawah. Penggunaan light trap membantu mengurangi jumlah hama yang masuk ke lahan sawah tanpa mengandalkan pestisida.
Kata kunci: Energi surya, light trap, pestisida, sawah.
ABSTRACT
The use of light traps as an effort to reduce the use of synthetic pesticides in environmentally friendly pest control is a more effective alternative in controlling the population and spread of insect pests. This activity aims to provide regular assistance and guidance to Carawali Village farmer groups regarding the application of light traps in the field. This community service activity includes being held in January - March 2023 in the village of Carawali, Kec. Watang Pulu, Sidenreng Rappang Regency. Activities include: a.) Observation and site surveys; b) Socialization; c) Implementation of assistance; d) Observation, and e) Monitoring and Evaluation. The results of observing the catch of solar energy-based light traps that have been installed in farmers' paddy fields show quite a lot of catches and after the 4th week the population of insect pests in the rice planting area decreases. the use of solar energy-based light traps is an effective solution to reduce the use of pesticides in paddy fields. The use of light traps helps reduce the number of pests that enter paddy fields without relying on pesticides.
Keywords: Solar cell, light traps, pesticide, ricefield.
KEKUATAN PEMBUKTIAN SEMPURNA AKTA NOTARIIL DALAM STUDI KASUS PUTUSAN NOMOR 260/PDT.G/2019/PN.SKT
Authors: Setyaning Khofifah , Harjono Harjono 
Published: May 2024

<p class="s5"><span>Penelitian ini bertujuan untuk menganalisis dan mengetahui kekuatan pembuktian akta notariil dalam proses peradilan dan akibat hukum dari dibatalkannya akta notariil oleh Pengadilan pada Putusan Nomor 260/Pdt.G/2019/PN.Skt. Penelitian ini merupakan penelitian hukum normatif yang bersifat deskriptif. Pada penelitian ini penulis menggunakan pendekatan studi kasus (<em>case study</em>). Dalam menulis penelitian ini menggunakan bahan hukum primer dan bahan hukum sekunder yang dikumpulkan dengan menggunakan teknik studi dokumen atau teknik studi kepustakaan yang kemudian dianalisis dengan menggunakan teknik seleksi dan klasifikasi menurut penggolongan bahan hukum. </span><span lang="ZH-CN">Hasil dari penelitian ini menunjukkan kekuatan pembuktian dari akta notariil adalah sempurna, artinya pembuktiannya cukup dengan menggunakan akta itu saja kecuali terdapat bukti lawan (<em>tegen bewijs</em>)</span><span lang="ZH-CN"> </span><span lang="ZH-CN">yang mengatakan sebaliknya. Akta notariil dalam proses peradilan dapat dibatalkan maupun batal demi hukum yang keduanya memiliki akibat hukum yang berbeda. Akta yang dibatalkan oleh pengadilan memiliki akibat hukum bahwa perbuatan hukum dalam akta notaris tersebut menjadi tidak berlaku</span><span> sejak dilakukan pembatalan</span><span lang="ZH-CN">. Sedangkan akta yang batal demi hukum dianggap tidak pernah dibuat. Pada putusan dengan nomor perkara 260/Pdt.G/2019/PN.Skt, surat kuasa dibuat dihadapan notaris sehingga merupakan akta otentik yang pembuktiannya sempurna dengan dinyatakan pihak yang melakukan perbuatan hukum dianggap telah melakukan sesuai dengan ketentuan yang berlaku. </span><span>Akan tetapi, terdapat bukti lawan sehingga s</span><span lang="ZH-CN">urat kuasa tersebut terbukti tidak memenuhi unsur kesepakatan (<em>error in person</em>)</span><span> dan</span><span lang="ZH-CN"> dibatalkan</span><span> oleh Pengadilan.</span></p>
Analysis of Changes and Influences Using Remote Sensing and Geodetectors on How Human Activity Affects Ulansuhai Lake Basin Ecology
Authors: Vengatesan Krishnasamy , Rajesh Manoharan , Kumar Eswaran Saravana 
Published: May 2024

Abstract

Investigating the Ulansuhai lake in southwest Inner Mongolia, China, this study uses a holistic approach that incorporates many datasets and approaches to evaluate the ecological environmental quality of the area. The specific geographical features and climate of the research region allow for a thorough examination of ecological changes through time. The research finds significant regional and temporal changes in ecological quality, with particular advances in some locations across the study period, through advanced data preparation approaches like remote sensing and model creation. The importance of comprehensive management approaches is highlighted by the fact that important variables including temperature, precipitation, land use patterns, and elevation are significant drivers of ecological health. In addition, the study highlights how complex ecological dynamics may be when multiple factors, including population density and economic conditions, interact with one another. Although this study sheds light on the Ulansuhai lake's ecological condition, it may be even better if future studies included other metrics, including as water quality and biodiversity, to round out the evaluation. In sum, the results of the study support the need for further research in this important area and provide a framework for long-term ecological management strategies in the area.
Synergistic Co-culture of Bacillus cereus and Clostridium acetobutylicum for Enhanced Biobutanol Production Utilizing Rice Husk: A Sustainable Approach to Biofuel Production
Authors: A Anuradha , Jayabalan Sudeepan , Sengupta Swaraj , Li Si-Yu , Sampath Muthu Kumar 
Published: May 2024

Abstract

Biobutanol, a promising biofuel with superior properties compared to ethanol, has garnered significant attention as an alternative to traditional fossil fuels. In the present study pretreatment of rice husk with deep euectic solvent using choline chloride and urea (ChCl/U) was investigated for the production of biobutanol. DES pretreatment and enzymatic hydrolysis yielded 30 ± 0.54 mg/ml of reducing sugar. This study also investigates the synergistic potential of co-culturing Bacillus cereus and Clostridium acetobutylicum for enhanced biobutanol production. B. cereus, known for its robust metabolism and extracellular enzyme secretion, is paired with C. acetobutylicum, a proficient butanol producer. The coculture produced 4.7 ± 0.69 g/l of biobutanol. The co-culture strategy aims to capitalize on the complementary metabolic capabilities of the two strains, facilitating improved substrate utilization and butanol production.
Valorization of waste wool to keratin with a green solvent based on a deep eutectic mixture of choline chloride and lactic acid
Authors: Anugwom Ikenna , Rissanen Tiina , Ora Ari , Pääkkönen Iirisi 
Published: May 2024

Abstract

Waste wool, a by-product of sheep husbandry, is primarily composed of keratin, which has potential use in cosmetic products, biotechnology and medical applications. Traditional chemical methods for keratin extraction face limitations due to health and environmental concerns, and thus, green alternatives such as deep eutectic solvents (DESs) have been developed. The aim of the present study was to determine whether a natural DES composed of choline chloride and lactic acid can be used to extract keratin from sheep wool. The dissolution and keratin yield were investigated under different reaction times, temperatures, and wool-to-DES ratios. Fractions of water-soluble keratin and water-insoluble keratin aggregates were obtained by dialysis, centrifugation, and drying. The results showed that both the dissolution of wool and the yield of recovered keratin increased as the reaction time and temperature increased from 1 to 8 h and from 80 to 110◦C, respectively.With the longest reaction time of 8 hours and the highest temperature of 110◦C, the yield of water-soluble keratin increased to 23 %. Characterizations revealed that DES detached first the cuticular scales from the surface of wool fibres and subsequently degraded wool cortex layer. The extracted water-soluble keratin retained the characteristic amide structure of wool, but the secondary structure of keratin was converted to cross-β sheet form. Moreover, it had a narrow size distribution and a molecular weight of 10 kDa. The results of this study indicate that the proposed DES can be used as a green solvent for recovering keratin from sheep wool.
The surveillance of antimicrobial resistance in wastewater using wastewater- based epidemiology approaches
Authors: Ntshanka Nokhanyo Mbewana , Msagati Titus Alfred makudali , Pierneef Rian , VanderWalt Marti , Mooa Thoriso , Nkosi Phiwinhlanhla , Matodzi Unarine , Mutshembele Awelani 
Published: May 2024

Abstract

Antimicrobial resistance (AMR) has become one of the top ten global public health threat. Many countries have recognized the societal and economic burden of AMR. The AMR has reduced the effectiveness of antimicrobial therapies and this results to high mortality, morbidity, and health care expenditure. Like all the other developing countries, South Africa (SA) falls under the same ambiguous management system of antimicrobials. A lot of research has been focused on the global public health threat “AMR”, however, studies on AMR in wastewater are limited. This paper highlights the imperatives of surveying the AMR pathogens in wastewater since wastewater are consecrated as hotspots for the dissemination and propagation of AMR genes. The RNA was extracted from the untreated wastewater samples that were collected from the Tshwane district in Gauteng province, SA. The metagenomic analysis was proposed for the analysis and profiling of the AMR genes present in the wastewater. A total of 39 AMR Gene Families and 39 AMR Drug Classes were detected across 17 samples. The metagenomic approach that is discussed in this paper demonstrate the importance of wastewater surveillance as it can be used as an early detecting system for communicable diseases as well as for monitoring wastewater.
Comparative RNAseq analysis for the study of motoneuron diseases in multi-omics approaches
Authors: Chen Sitong , Ulmer Ulrike , Synofzik Matthis , Schule Rebecca , Zuchner Stephan , Danzi Matt C. 
Published: May 2024

Abstract

Nearly half of patients with suspected monogenic Mendelian diseases still remain undiagnosed. The integration of genome sequencing and RNA sequencing can reveal the functional significance of rare changes. This is especially true for deep intronic non-coding variation that contributes to mis-splicing but is difficult to discern when analyzing whole genome data alone. However, this combined approach is challenged when studying motoneuron and other neurological diseases as obtaining affected tissue samples from living patients is typically not feasible. Here we explore the utility of typically available sources of material for RNAseq studies that can empower genome analysis. We found that fibroblasts cultured in vitro express 76.8%, 73.6%, and 81.2% of genes known to cause the monogenic diseases CMT, ataxia, and HSP, respectively. This outperformed other peripheral tissues such as whole blood and lymphocytes, thereby making fibroblasts a valuable tissue for studying motoneuron diseases. Only induced pluripotent stem cell (iPSC)-derived cortical neurons showed a higher number of expressed known disease genes; however, derived cortical neurons require significant resources and time. Finally, we analyzed RNA-seq data from fibroblasts of two HSP patients carrying a deep intronic splice disrupting variant in POLR3A, to evaluate the sensitivity and specificity of several alternative splicing detection tools for diagnostic purposes. Our results highlight the potential of fibroblast RNA-seq data for diagnosing and studying HSP and other motoneuron and neurological diseases using peripheral tissue.
The Relationship between Perceived Social Support, Psychological Capital, Job Burnout, and Work Engagement in Nurses Working On The Front Line Of The Fight Against The Coronavirus
Authors: Rahgoi Abolfazl , Fallahi-Khoshknab Masoud , Vahedi Mohsen , Jannati Yadollah , amiri fatemeh 
Published: May 2024

Abstract

Background
Due to the coronavirus epidemic, nurses on the front line of caring for infected patients are always faced with many job stressors, and one of the most inevitable consequences is job burnout, which can cause challenges for work engagement. This study used structural equation modeling to determine the effects of psychological capital and perceived social support on job burnout and work.
Methods
This study was a cross-sectional descriptive-analytical type. 306 nurses on the frontline of the fight against the coronavirus in the public hospitals of Mazandaran University of Medical Sciences were selected by multi-stage random stratification. The data collection process lasted from September 19 to November 19, 2021. To collect data from Zimet et al. perceived social support questionnaire, Lutans psychological capital questionnaire, Utrecht work engagement scale, and Maslach burnout inventory. PLS3 and SPSS25 software were used to analyze the data. This study was approved by the Ethics Committee of the University of Social welfare and Rehabilitation under the number IR.USWR.REC.1400.105.
Results
More than half of the people were women, married, under 40 years old, with a bachelor's degree, with over 10 years of work experience, and over one year of experience in corona departments. The fit indices of the research model were favorable (GOF > 0.529) and the research model fit was confirmed. Also, based on the path coefficient there was a significant negative relationship between perceived social support with job burnout (β=-0/115) and psychological capital with job burnout (β=-0/503) and a significant positive relationship between perceived social support with work engagement (β = 0/132) and between psychological capital with work engagement (β = 0/607) (P˂0.05).
Conclusions
Considering the inevitable effect of perceived social support and psychological capital on reducing job burnout and increasing work engagement; our findings can be used To develop the occupational health of employees and then to develop the quality of health care services by health managers and policymakers. Also, interventions based on social support and psychological capital can be identified and studied as a new area for effective psychological interventions among nurses.
Clinical significance of serum helicobacter pylori antibody cytotoxin-associated gene A levels in patients with unstable angina
Authors: Jia Haizhen , Fan Huajun , Zhao Jinhe , Peng Jun , Pan Yunhong , Peng Hongyan 
Published: May 2024

Abstract

Objective: We investigated the clinical significance of serum Helicobacter pylori cytotoxin-associated gene A (CagA) antibody levels in 768 patients with unstable angina (UA).
Methods: Serum CagA levels were measured using ELISA. Demographic data, serum biomarkers, and SYNTAX scores were collected. Patients were followed up for one year for major adverse cardiac events (MACE).
Results: CagA-positive UA patients had higher total cholesterol and hsCRP levels, and SYNTAX scores. CagA levels correlated positively with TC, hsCRP, and SYNTAX scores. Kaplan-Meier analysis showed shorter MACE-free survival in CagA-positive UA patients. CagA levels predicted MACE occurrence within one year, along with SYNTAX scores. Conclusion: Serum H. pylori CagA antibody positivity is associated with worse prognosis in UA patients. CagA levels correlate with lipid metabolism and inflammatory markers.
Regio- and diastereoselective synthesis of thioxothiazolidin- indolin-2-ones, oxoindolin-carbamodithioate hybrids, and their base-catalyzed conversion into dispirocyclopentanebisoxindoles
Authors: Aghamiri Bagher , Moghaddam F. Matloubi , Badpa Sara , Kavoosi Leila 
Published: May 2024

Abstract

In this publication, we reported a regio-, diastereoselective, and kinetically controlled reaction for synthesizing thioxothiazolidin-indolin-2-ones, oxoindolin-carbamodithioate hybrids, and their base-catalyzed conversion into dispirocyclopentanebisoxindoles. Obtaining only the kinetic thioxothiazolidin-indolin-2-one products together with their straightforward conversion to dispirocyclopentanebisoxindoles, excellent regio- and diastereoselectivity, easy reaction workup, and one-pot synthetic operation are considerable advantages of this work.
Divergent consequences of Extracellular tau on the mitochondrial function of astrocytes and neurons
Authors: Zufferey Valentin , Parietti Enea , Barve Aatmika , Espourteille Jeanne , Varisco Yvan , Fabbri Kerstin , Capotosti Francesca , Preitner Nicolas , Richetin Kevin 
Published: May 2024

Abstract

Background Tauopathies encompass a spectrum of neurodegenerative disorders which are marked by the pathological aggregation of tau protein into paired helical filaments (PHF-tau), neurofibrillary tangles (NFTs) and Glial-fibrillary tangles (GFTs). These aggregates impair cellular, mitochondrial, and synaptic functions. The emergence of extracellular tau (ePHF-tau), featuring a myriad of isoforms and phosphorylation states, presents a challenge in comprehending its nuanced effects on neural cells, particularly concerning synaptic and mitochondrial integrity.Methods We studied the impact of ePHF-tau (2N4R) on different states and ages of primary cultures of rat neuroglia. Using confocal microscopy and proteomic analysis of synaptosomes, we studied the impact of ePHF-tau on neurite and synapse number. We monitored mitochondrial responses in neurons and astrocytes over 72 hours using advanced fluorescence microscopy for dynamic, high-throughput analysis.Results Treatment with ePHF-tau has a strong effect on the neurites of immature neurons, but its toxicity is negligible when the neurons are more mature. At the mature stage of their development, we observed a substantial increase in the density of the PSD-95/vGlut1 zone in neurite, suggesting altered synaptic connectivity and ePHF-tau excitotoxicity. Proteomics revealed significant changes in mitochondrial protein in synaptosomes following exposure to ePHF-tau. In the neuronal compartment, real-time imaging revealed rapid and persistent mitochondrial dysfunction, increased ATP production, and reduced mitochondrial turnover. In contrast, we observed increased mitochondrial turnover and filamentation after treatment in the astrocyte processes, indicating cell-specific adaptive responses to ePHF-tau.Conclusions This study sheds light on the intricate effects of extracellular tau aggregates on neuronal and astrocytic mitochondrial populations, highlighting how tau pathology can lead to mitochondrial disturbances and synaptic alterations. By delineating the differential responses of neurons and astrocytes to ePHF-tau, our findings pave the way for developing targeted therapeutic interventions to mitigate the detrimental impacts of tau aggregates in neurodegenerative diseases.
Finite element analysis of a new alveolar bone splitting technique in the mandibular posterior region
Authors: Tian Ye , Shi Xiaolu , Zhai Shaobo , Liu Yang , Yang Zheng , Wu Yuchuan , Chu Shunli 
Published: May 2024

Abstract

Background: Finite element analysis was used to predict the risk of bone plate fracture and the expected bone augmentation effect of a new alveolar bone splitting technique in the mandibular posterior region for different alveolar crest widths, different alveolar bone densities, different root incision widths, and different insertion depths of bone expansion instrumentation.
Methods: The jaw models of the mandibular posterior region were constructed by computer-aided software and surgical incisions and bone expansion instruments were prepared on the models, after which the alveolar bone splitting procedure was simulated by finite element analysis software, and the equivalent stress-strain distribution characteristics of the jaw models of each group, as well as the maximal force and the maximal displacement of the bone plate when it was fractured, were recorded.
Results: The distribution of equivalent stress and strain was mainly concentrated in the cancellous bone area at the root incision and the lower 1/3 of the buccal cortical bone plate, and there was no significant difference in the stress-strain distribution characteristics of the jaw models of each group. The wider of the alveolar crest, the higher the force required to fracture the bone plate, but the smaller the maximum displacement; the plastic deformation capacity of type IV bone jaws was more excellent; the wider the width of the root incision, the shallower the depth of instrument insertion, and the larger the maximum displacement.
Conclusion: Finite element analysis can effectively simulate the surgical criticality index of the new alveolar bone splitting procedure. Alveolar crest width, alveolar bone density, root incision width, and instrument insertion depth had a clear correlation with the maximum displacement of the bone plate at fracture. The alveolar crest width and alveolar bone density also had a significant effect on the maximum force required to fracture the bone plate.