bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of state protection for urban passenger transport enterprises
Authors: Palant Oleksii , Zakharov Denys 
Published: May 2024

This paper considers the task to provide state financial protectionism under the conditions of today's challenges. A model of effective interaction is proposed, which takes into account selective fair financing based on indicators of the investment attractiveness of the i-th region and the priority of the i-th region. The calculations proved the independence of the regional financing priority indicator on the level of investment attractiveness of the region, or vice versa. The methodology was tested on the example of urban passenger transportation entrepreneurship under the conditions of challenges that have arisen. According to the results, those territories that are recognized as the most affected and vulnerable, and the problem of support of which can be solved only with the help of state intervention, are eligible for state protectionism.
The results of the calculations show that the distribution of financial funds in the amount of state finances S=1 allocated to support entrepreneurship is carried out proportionally. A comprehensive approach made it possible to determine the regions for state funding, while the most affected regions receive the largest share of financial investments – Luhansk, Chernivtsi, Kherson, Donetsk, Mykolaiv, and Sumy oblasts, which will receive funding to support urban passenger transportation, in the amount of 17.01 %, 16.89 %, 16.74 %, 16.57 %, 16.55 %, and 16.24 %, respectively.
This study is of practical interest for state management bodies as it provides methodological recommendations for the allocation of funds to support the most affected regions. It is also useful for researchers studying financial provision, protectionism, and public administration, and it is recommended that future research be conducted taking into account the level of socio-economic development of states
Estimating the influence of research and development expenditures on the income of companies revenue in the field of engineering of innovative developments under the conditions of changing project management methodology
Authors: Myronenko Oleksii 
Published: May 2024

The choice of project management methodology affects both the implementation of projects and their economic efficiency. Quantitative assessment of such an impact substantiates the relevance of this paper's research topic. The object of the study is the activity of companies in the field of engineering of innovative developments under the conditions of change in project management methodology. The study solved the problem of identifying the impact of research and development costs on the income of companies in the field of innovative development engineering in the context of a change in project management methodology. A change in project management methodology can significantly affect the costs, timelines, and bottom line associated with research and development, and determine their effectiveness in the context of achieving business goals. A change in project management methodology can affect the use of resources allocated for research and development, which ultimately affects the company's performance. Regression analysis was used to determine the impact of changes in project management methodology on the amount of investment in research and development. The results of the study show that the use of project management methodologies, such as Waterfall and Agile, has a positive effect on the quality of project management and financial indicators of companies. Projects implemented according to the Agile methodology are more effective, reducing the number of canceled and closed projects. Both methodologies lead to the successful completion of most projects but the percentage of successfully completed projects with the Waterfall methodology is higher than with Agile. The use of Agile makes it possible to achieve a significant reduction in the terms of project implementation and improve the efficiency of costs and resources. The results can be used by companies at the stage of choosing a project management methodology to decide on the implementation of the Waterfall or Agile methodology
Synthesis of IR780-chlorambucil as a photosensitiser for treating MCF-7 and HepG2 cancer cells
Authors: Le-Van Dung , Nguyen Hong-Phuc , Le-Tuan Loc , Tran-Anh Vy , Nguyen Thanh-Danh , Vu-Quang Hieu 
Published: May 2024

Phototherapy is a targeted method for eradicating cancer cells with minimum collateral harm to healthy tissue. The method requires a photosensitiser for cancer realtime monitoring and treatment. Photosensitiser which composes from fluorophore and chemodrug would be an advantage compares to another since it could play many roles such as giving the image of cancer, generating the heat and releasing the drug to kill the cancer cells. IR-780 iodide, heptamethine Cyanine dye, has been used as an ideal platform to construct theranostic agents for cancer imaging and therapy. Chlorambucil (CHL) is an effective chemodrug for cancer therapy which have been ultilized for conjugation to synthesis new drug. Thus, in this study we report a study that combines IR780 and CHL for phototherapy purpose. The new synthesis of IR780-CHL has been confirm the structure by liquid chromatography – mass spectrum (LC-MS) and 1H nuclear magnetic resonance (1H NMR). The LC-MS findings indicated a mass of 616.35 MW, which corresponded to our predicted fraction. While the 1H NMR demonstrated the presence of resonant peaks in IR780-CHL that are exclusive to CHL and IR780. UV-Vis measurements have revealed that the absorbance of IR780-CHL has moved to 756 nm instead of 780 nm. Before and after laser activation, the toxicity of IR780-CHL was comparable to that of CHL, indicating that the synthesis did not influence the in vitro effectiveness of the drug treatment. The development of IR780-CHL has considerable potential for cancer detection and treatment.
Irrationality vs rationality? Irrationality as a door to the rational Greek thought
Authors: Faluszczak-Skrzypek Jadwiga 
Published: May 2024

The origin of western thought is commonly situated in Greek philosophy, with the over-arching story of logos-based rational inquiry deteriorating from the mythical stories presenting supernatural cause to the observable phenomena. This paper aims to investigate the intersection of rational and irrational factors contributing to the emergence of philosophy. Author proceeds through the examination of Ionian, Pythagorean and Orphic thought, all shaping the most influential works of Greek philosophers, such as Plato. The theoretical base of the study was embedded in the writings of Rudolf Otto and Francis M. Cornford. In result, the conclusions present the irrationality as a root for rational interpretation of reality, through the commonality endeavour of both, aiming at the elevation of human figure, its independence from chaotic actions of gods and revelation of the higher truths through the embodied means of ritual action as well as through the thinking process of ordering and synthetizing. The examples brough by the author expose the intertwining of religious belief and philosophical thought.
Wyznania wiary synodu w Antiochii z 341 roku
Authors: Baron Arkadiusz 
Published: May 2024

Dokumenty synodu w Antiochii z 341 roku zawierają cztery wyznania wiary. Są one reakcją na oskarżenia biskupów Wschodu o arianizm ze strony synodu w Rzymie w 340/341 roku. Zarzuty te powstały w rezultacie obrony Atanazego z Aleksandrii i Marcelego z Ancyry, złożonych na Wschodzie z urzędu rzekomo za obronę wyznania wiary z Nicei z 325 roku przeciwko ariańskim poglądom szerzącym się na Wschodzie. Tymczasem Wschód borykał się z różnymi formami monarchianizmu. Zarzuty wobec biskupów Wschodu o arianizm stanowiły nieporozumienie na linii Rzym–Antiochia i wywołały szybką reakcję biskupów na synodzie w Antiochii w 341 roku. Cztery formuły wiary tego synodu zapoczątkowały serię tworzenia nowych wyznań wiary w następnych latach i stanowią cenny wkład na drodze wypracowywania w połowie IV wieku prawdy wiary, że wyznajemy Jednego Boga w Trzech Osobach.
STUDY OF DOUGH FERMENTATION PROCESS WITH FLAX SEEDS
Authors: Bondarenko Yu. , Andronovych G. , Kaprelyants L. , Bilyk O. , Naumenko O. 
Published: May 2024

Flax seeds are a valuable raw material for the production of functional bakery products. The article investigates the fermentation processes in wheat dough supplemented with whole and crushed flax seeds in dry and soaked states. For a holistic understanding of the fermentation process, the regularities of the kinetics and dynamics of gas formation in the experimental samples were analyzed. It was found that during fermentation in samples with whole flax seeds in dry and soaked states, the amount of carbon dioxide released slightly increases compared to the control. In the samples with crushed dry and soaked flax seeds, the total amount of carbon dioxide released is higher than in the control sample by 16.5% and 19.0%, respectively. In the sample with crushed flax seeds, the nature of the dynamics of carbon dioxide release differs from the control sample, namely, a one-stage fermentation is observed. At the same time, the peak of carbon dioxide release was observed almost 30 minutes later than in the control sample. This may be due to the fact that soaking flaxseed products produces viscous solutions of polysaccharides, which envelop the yeast cells during dough kneading and slow down the supply of nutrients to them. Based on the analysis of the dynamics of carbon dioxide emission, it is recommended to reduce the duration of dough fermentation for the sample with whole flax seeds to 90 minutes, and for the samples with crushed seeds and soaked flax products to 60 minutes, so that the most intense carbon dioxide emission in these experimental samples occurs during the period of proofing of dough pieces. It was found that the introduction of whole and crushed flax seeds in soaked form slows down the rise of the dough due to the thickening of the dough system with water-soluble and insoluble flax dietary fiber, reducing fermentation and the formation of sugars in the dough system.
TIA NASTÁCIA, DE MONTEIRO LOBATO: ENTRE O PROTAGONISMO E O APAGAMENTO CULTURAL
Authors: Silva Telma Borges da , Lima Maria da Penha Brandim de 
Published: May 2024

Em Histórias da Tia Nastácia (2018), a personagem do título é a contadora de histórias da tradição popular e folclórica brasileiras. Neste trabalho discute-se a desqualificação de tia Nastácia no processo de silenciamento de sua voz, uma representante coletiva dos negros e de sua cultura ancestral. Michel Foucault (2013), e Eni Orlandi (2007) apresentam os sentidos do silêncio trabalhando a forma de sua existência e sua significação, as quais se constroem em situações específicas, que definem o modo de significar, delineadas na cena enunciativa (Maingueneau, 2015, 2008). Monteiro Lobato concede a Tia Nastácia, em tese, a possibilidade de uma espécie de protagonismo como narradora de histórias tradicionais, mas, ao mesmo tempo, faz com que a voz da boneca de pano humanizada o anule, sendo o nome da personagem exemplar desse silenciamento. Para esta análise, propomos o estudo da Cena Enunciativa como elemento fundamental em uma análise discursiva, além de indicações de cunho lexical na caracterização das personagens, pois ao confrontar os significados de seus nomes, observa-se a construção de uma alegoria de discurso colonial sobre o Brasil e sua formação histórico-cultural, silenciadora de vozes outras, como a de Tia Nastácia.
Deferred Expenses: Problematic Aspects and Prospects for the Convergence of Accounting in the Public and Private Sectors of the Economy
Authors: Arbatskaya Tatyana , Putyrskaya Yana 
Published: May 2024

Currently, in both the private and public sectors of the economy, one of the debatable objects of accounting, along with deferred income, are deferred expenses. The article analyzes the requirements of regulatory legal acts and the viewpoints of various economists regarding the accounting object of deferred expenses, as well as the grounds for their occurrence. The authors’ opinions regarding deferred expenses are opposed diametrically. Some authors believe that deferred expenses should not exist in national accounting practice, others consider their use acceptable in a number of cases. As a result, of the study, it was concluded that in connection with the entry into force of new federal accounting standards, the list of cases for reflecting deferred expenses in the private sector of the economy has significantly narrowed. At the same time, in the public sector organizations there are much more grounds for qualifying objects as deferred expenses. As a result, of the study, differences were revealed in the emergence and formation of accounting information when reflecting certain types of expenses — for non-exclusive rights to software, expenses for paying vacation pay, expenses for voluntary medical insurance. At the same time, in the private sector, only expenses for licensed software are recognized as deferred expenses and only until the entry into force of FSBU 14/2022 «Intangible Assets». It is recommended to develop a unified methodological approach to accounting for deferred expenses both in commercial and public sector organizations.
Does transanal endomicrosurgery affects the results of “salvage mesorectumectomy” for patients with early rectal cancer? Systematic review and meta-analysis
Authors: Kirgizov Ph. I. , Chernyshov S. V. , Nagudov M. A. , Rybakov E. G. 
Published: May 2024

Aim. Our systematic review and meta-analysis aimed to compare studies with primary mesorectumectomy (pME) and “salvage mesorectumectomy” (sME) after transanal endomicrosurgery for patients with early rectal cancer.Materials and methods. We selected publications from 1 January 1999 to 1 April 2023. A total of 7 studies were included after screening. Following indicators were compared: quality of mesorectum, frequency of abdominoperineal resection, frequency of local recurrence and distant metastases, mortality, morbidity, time of surgery, post-operative stay, frequency of involvement of circular resection margin. Statistical data was processed using ReviewManager 5.3.Results. Statistically significant differences were observed in probability of intraoperative damaging of mesorectal fascia (Odds Ratio (OR) 0.42; 95 % Confidence Interval (CI) 0.24–0.72, р = 0.002). There were also a trend towards decreasing of number of sphincter-preserving operations after transanal endomicrosurgery (TEM) (OR 1.84; 95 % CI 0.96–3.52, р = 0,06). Other indicators didn’t reach statistical significance when compared.Conclusion. sTME is a safe procedure and comparable with pME. However, previous TEM is considered a risk factor for damaging of mesorectum, intraoperative perforation and abdominoperineal resection.
Organ-preserving treatment of a patient with a trophoblastic tumor of the placental bed (clinical observation and literature review)
Authors: Tikhonovskaya M. N. , Rumyantsev A. A. , Kappusheva L. M. , Shevchuk A. S. 
Published: May 2024

Placental site trophoblastic tumor (PSTT) is а rare form of gestational trophoblastic neoplasia (GTN), accounting 0,2 % of total cases of GTN. PSTTs occur in women of childbearing age and most of them have strong desire to preserve fertility. PSSTs are tumors with unpredictable biological behavior, high chemo-resistance and possibly fatal outcome in case of metastatic disease.Hysterectomy is the primary treatment of choice in early disease. We report a rare clinical case of fertility sparing treatment for PSTT.
A cadaveric study of superior sagittal sinus and its draining veins among population in Sabah, Malaysia
Authors: Arumugam Ananda , Thillynathan Vicnesh , Velayudhan Dewaraj , Hiu Jessie , Abdelwahab Emad. M.N 
Published: May 2024

The superior sagittal sinus and its draining veins are important venous structures that pose a formidable obstacle to surgical management. It is crucial and essential for the surgeon to acquire the knowledge of the normal course and variations of the sinus and its draining veins. This helps in pre-operative planning and execution of pre-operative measures or manoeuvres needed to minimize blood loss or intra-operative injuries to the sinus.This study was conducted to delineate the microsurgical anatomy of the superior sagittal sinus to look for any variations among Sabah people as compared to the general studies available. This study was based on dissection of fresh cadavers. Thirty fresh cadavers were examined in Forensic Department, Hospital Queen Elizabeth, Sabah between August 2020 to June 2021. They were anatomically analysed and studied through a data collection sheet. All data were analysed using Statistical Package for the Social Science (SPSS). The study revealed that male was predominantly significant and forty-three percent were of Bajau race. Fifty percent of cadavers were around the 50-60 years old age group. The position of superior sagittal sinus (SSS) was variable and within 1cm distance from the midline. The origin of SSS varied from at the foramen caecum to posterior from the foramen caecum. The total length of SSS averages around 321-351mm. The number of draining veins on the right and left side of SSS were divided into anterior, middle and posterior components with an average of three to six veins respectively on each side. The number of venous lacunae on the right and left side of SSS were divided as well into anterior, middle and posterior components with an average of one to two venous lacunae on each side respectively. The central sulcus was located 48.87mm posterior to coronal suture and 131.1mm anterior to the lambdoid suture. The Trolard vein was located 53.56mm posterior to coronal suture and 127.36mm anterior to the lambdoid suture. The Trolard vein was situated in average 3.68mm posterior to central sulcus and predominantly drains into the venous lacuna. Ninety percent of SSS terminate on the right of the transverse sinus. The position of torcula varies from the location on the external occipital protuberance to slightly on the right side of the external occipital protuberance. This study shows that anatomical landmarks among the local population did not differ significantly from that reported by other studies throughout the world. Therefore, the basic neurosurgical principles and craniometric points outlined universally is applicable to this population without the need for any modifications.
A systematic review on prosthodontic rehabilitation of hemimandibulectomy patients
Authors: Soni Aishwarya , Damade Shreyans , Parlani Swapnil , Bisen Aishwarya 
Published: May 2024

To restore oral function after tumor excision, practitioners must undertake the enormous challenge of restoring hemimandibulectomy deficits. Depending on the type and extent of mandibular reconstruction (Cantor-Curtis classification), there are many prosthetic treatment options available for the rehabilitation of acquired hemimandibulectomy abnormalities. The objective of this systematic study is to evaluate the range of prosthodontic rehabilitation techniques in relation to the kind of repair and severity of mandibular surgical abnormalities. The databases incorporated for literature search were Google Scholar and Medline (PubMed). Relevant search terms for hemimandibulectomy and reconstruction with prosthetic rehabilitation were used. Two reviewers independently assessed the articles using eligibility criteria; published case reports and case series in the English language and depicting prosthodontic treatment modality of patients greater than 13 years were included. A total of 212 records were identified from the database search of which 29 duplicates were removed.The remaining articles were assessed for eligibility, and 50 articles (comprising 50 cases) were finally included in the study. This review identified a number of prosthetic options, including some novel prosthetic techniques, guiding flange, twin occlusion, palatal ramp, conventional to hybrid partial and complete dentures, and implant-supported prosthesis.The prosthetic options covered in this review included implant-supported prosthesis, guide flange, dual occlusion, palatal ramp, conventional, hybrid, and full dentures, as well as a few cutting-edge prosthetic techniques.As they plan and manage sequential therapy for hemimandibulectomy cases in their daily practice, practitioners and prosthodontists will find this helpful.
Does addition of intravitreal bevacizumab confer additional benefit in management of proliferative diabetic retinopathy?
Authors: Radhakrishnan Natasha , Pillai Gopal S , Kandula Pooja , Nair Mira 
Published: May 2024

To evaluate visual outcome and complications of PDR after treatment with Intravitreal Bevacizumab followed by Pan Retinal Photocoagulation A hospital based retrospective study was done in the Department of Ophthalmology, to evaluate visual outcome and complications of PDR after treatment with intravitreal Bevacizumab followed by Pan Retinal Photocoagulation. Visual Acuity, Dilated fundus examination, OCT macula were done on subsequent follow ups 135 eyes of 133 patients were included in the study.The mean pre procedure visual acuity is 0.639±0.5327 which improved to 0.451±0.4089 post procedure. P value is &#60;0.001 which is statistically significant.i.e, 94 (69.62%) eyes had improved vision, 21(15.55%) had stable vision and 20(14.81%) eyes had decreased vision. After injection followed by PRP out of 135 eyes,4(2.96%) eyes developed vitreous hemorrhage which resolved with repeat intravitreal anti-VEGF injection, 6(4.44%) eyes developed diabetic macular edema,3(2.2%) eyes developed Neovascularisation of iris and 4(2.96%)eyes developed vitreous hemorrhage with traction retinal detachment.From our study it appears that addition of intravitreal anti VEGF to Pan Retinal Photocoagulation for PDR confers the additional benefit of less incidence of vitreous hemorrhage and less incidence of traction retinal detachment requiring surgery in the 1 one year of follow up. This amounts to more compliance by the patient for taking the treatment as well as better visual outcome