bluuebunny/crossref_metadata_2025_split huggingface dataset:
Posterior fossa involvement in a recurrent gliosarcoma
Authors: Balasubramaniam Srikant , Tyagi Devendra K , Sawant Hemant V , Epari Sridhar 
Published: January 2012

ABSTRACTGliosarcoma (GSM) is a WHO grade 4 tumor and a variant of glioblastoma multiforme with predilection for the temporal lobe. We record, perhaps the first case in literature, of a temporal lobe GSM with recurrence involving the posterior fossa. A 50-year-old man presented to us with headache, vomiting, and lethargy of relatively recent onset. Magnetic resonance imaging revealed a well-circumscribed lesion in the left temporal lobe for which left temporal craniotomy with radical excision of the tumor was performed. Histopathology was suggestive of GSM. He presented to us within a month of the first surgery with a large recurrence involving the temporal lobe. He underwent a second surgery with radical excision of the tumor. Histopathology was confirmatory of GSM. He was administered concomitant chemotherapy and radiotherapy. Within a fortnight of starting adjuvant therapy, the bone flap started bulging and a repeat computed tomography scan revealed a large recurrence extending into the posterior fossa. The patient′s relatives refused consent for third surgery and he finally succumbed on postoperative day 21. GSMs are aggressive tumors that have a temporal lobe predilection, but they may present anywhere in the brain. Detailed studies on larger cohort of cases are needed to understand the true nature of these biphasic tumors.
Frontonasal dysplasia (Median cleft face syndrome)
Authors: Sharma Seema , Sharma Vipin , Bothra Meenakshi 
Published: January 2012

ABSTRACTThis is a report of a rare case of frontonasal dysplasia (FND) in a full-term girl with birth weight of 2.750 kg. The baby had the classical features of FND. There were no other associated anomalies. There was no history of consanguinity and no family history of similar conditions. So inheritance of this case could be considered sporadic. Maxillofacial surgery should be considered for all patients for whom improvement is possible. However, in developing countries where there are considerable limitations in provision of social services, with economic and educational constraints, correction of such major defects remains a challenging task.
Perioperative challenges in patients with giant occipital encephalocele with microcephaly and micrognathia
Authors: Hukum Singh , Singh Daljit , Sharma D.P. , Tandon Monica S , Ganjoo Pragati 
Published: January 2012

ABSTRACTMeninigo-encepahlocoele (MEC ) is a common neurosurgical operation. The size of MEC may vary which has bearing with its management. The association of MEC with micrognathia and microcephaly is rarely reported. The association poses special problem for intubation and maintenance of anaesthesia. Giant MEC may lead to significant CSF loss resulting in hemodynamic alteration. The prior knowledge and care in handling the patient can avoid minor as well as major complications.
Riboflavin's Time-Dependent Degradation Rate Induced by Ultraviolet a Irradiation
Authors: Diakonis Vasilios F. , Grentzelos Michael A. , Tzatzarakis Manolis N. , Kankaria Vardhaman , Karavitaki Alexandra , Karatapanis Andreas E. , Tsatsakis Aristidis M. , Kymionis George D. 
Published: January 2012

Purpose To evaluate the time-dependent degradation rate of riboflavin after ultraviolet A (UVA) irradiation. Methods Two solutions of commercially available riboflavin solution (0.1%) were used; one served as control, while the second was irradiated using UVA light at 370 nm wavelength. Four samples of riboflavin solution were retrieved prior to irradiance and at 1, 5, 15, 30, and 60 minutes after irradiation (group A); at the same time points samples of riboflavin were retrieved from the control solution in order to assess environmental time-induced degradation of riboflavin (group B). All samples were immediately analyzed using liquid chromatograph mass spectrometry to detect riboflavin and its 2 subproducts, lumiflavin (LF) and lumichrome (LC). Results Mean percentage of riboflavin degradation was 0.0, 5.3, 9.1, 15.3, 20.6, and 33.3 at 0, 1, 5, 15, 30, and 60 minutes after UVA irradiation, respectively (group A). The time-dependent riboflavin degradation was statistically significant (p<0.05), while for group B there was no change in riboflavin concentration at all time intervals. In group A, mean LC concentration demonstrated a gradual concentration increase, reaching 2.386±1.526 ppm after 60 minutes of UVA exposure. Conclusions The time-dependent degradation of riboflavin solution is significant, reaching 20.6% after 30 minutes of UVA exposure. It seems that only a small fraction of the overall riboflavin molecules break down since more than 65% remain intact even after 1 hour of UVA irradiation. Control riboflavin solution seems to be stable, as no degradation is evident even after 60 minutes.
Contenidos audiovisuales y televisivos para dispositivos móviles: una aproximación al mercado español
Authors: Adelantado Eulalia , Martí José 
Published: January 2012

En el actual contexto mediático de convergencia digital y difusión multipantalla, los dispositivos móviles están adquiriendo un creciente protagonismo como punto de acceso a contenidos audiovisuales y televisivos, en especial aquellos contenidos relacionados con el entretenimiento. Este artículo examina las principales ventajas y limitaciones que presentan los dispositivos móviles como una nueva pantalla para la difusión de este tipo de contenidos. Para ello se ha realizado un análisis exploratorio de los contenidos audiovisuales de entretenimiento que han sido distribuidos en el mercado español desde los primeros formatos nativos del medio, como las moviseries y los realities shows, hasta la oferta actual de contenidos televisivos, así como las nuevas aplicaciones y contenidos surgidos con la consolidación de Internet móvil. La exploración realizada ha permitido identificar las principales tendencias y modelos de negocio surgidos en torno a estos contenidos, en especial aquellos relacionados con el emergente mercado de las aplicaciones para móviles. Del mismo modo ha permitido también señalar los principales factores, tanto tecnológicos como relativos al mercado, que pueden estar impidiendo un mayor uso de la telefonía móvil como plataforma de difusión de contenidos audiovisuales y televisivos.
Lifecycle Management for Sustainable Plastics: Recent Progress from Synthesis, Processing to Upcycling
Authors: Yang Shuangqiao , Li Yijun , Nie Min , Liu Xingang , Wang Qi , Chen Ning , Zhang Chuhong 
Published: June 2024

AbstractPlastics, renowned for their outstanding properties and extensive applications, assume an indispensable and irreplaceable role in modern society. However, the ubiquitous consumption of plastic items has led to a growing accumulation of plastic waste. Unreasonable practices in the production, utilization, and recycling of plastics have led to substantial energy resource depletion and environmental pollution. Herein, the state‐of‐the‐art advancements in the lifecycle management of plastics are timely reviewed. Unlike typical reviews focused on plastic recycling, this work presents an in‐depth analysis of the entire lifecycle of plastics, covering the whole process from synthesis, processing, to ultimate disposal. The primary emphasis lies on selecting judicious strategies and methodologies at each lifecycle stage to mitigate the adverse environmental impact of waste plastics. Specifically, the article delineates the rationale, methods, and advancements realized in various lifecycle stages through both physical and chemical recycling pathways. The focal point is the attainment of optimal recycling rates for waste plastics, thereby alleviating the ecological burden of plastic pollution. By scrutinizing the entire lifecycle of plastics, the article aims to furnish comprehensive solutions for reducing plastic pollution and fostering sustainability across all facets of plastic production, utilization, and disposal.
Rare‐Earth‐Metal‐Free Solid‐State Fluorescent Carbonized‐Polymer Microspheres for Unclonable Anti‐Counterfeit Whispering‐Gallery Emissions from Red to Near‐Infrared Wavelengths
Authors: Barman Barun Kumar , Yamada Hiroyuki , Watanabe Keisuke , Deguchi Kenzo , Ohki Shinobu , Hashi Kenjiro , Goto Atsushi , Nagao Tadaaki 
Published: June 2024

AbstractColloidal carbon dots (CDs) have garnered much attention as metal‐free photoluminescent nanomaterials, yet creation of solid‐state fluorescent (SSF) materials emitting in the deep red (DR) to near‐infrared (NIR) range poses a significant challenge with practical implications. To address this challenge and to engineer photonic functionalities, a micro‐resonator architecture is developed using carbonized polymer microspheres (CPMs), evolved from conventional colloidal nanodots. Gram‐scale production of CPMs utilizes controlled microscopic phase separation facilitated by natural peptide cross‐linking during hydrothermal processing. The resulting microstructure effectively suppresses aggregation‐induced quenching (AIQ), enabling strong solid‐state light emission. Both experimental and theoretical analysis support a role for extended π‐conjugated polycyclic aromatic hydrocarbons (PAHs) trapped within these microstructures, which exhibit a progressive red shift in light absorption/emission toward the NIR range. Moreover, the highly spherical shape of CPMs endows them with innate photonic functionalities in combination with their intrinsic CD‐based attributes. Harnessing their excitation wavelength‐dependent photoluminescent (PL) property, a single CPM exhibits whispering‐gallery modes (WGMs) that are emission‐tunable from the DR to the NIR. This type of newly developed microresonator can serve as, for example, unclonable anti‐counterfeiting labels. This innovative cross‐cutting approach, combining photonics and chemistry, offers robust, bottom‐up, built‐in photonic functionality with diverse NIR applications.
More efficient nitrogen utilization through wool pellet and soil inoculation
Authors: Kovács Flórián , Papdi Enikő , Veres Andrea , Mohay Piroska , Szegő Anita , Juhos Katalin 
Published: June 2024

AbstractIn recent years, many alternative bio‐waste‐based fertilizers have been proven to have a beneficial effect on plant nutrition. These also include wool pellet, whose comprehensive evaluation of synergistic effects on plant development and soil biological activity is still a limited field of investigation. To address this, we explored the potential of combining soil inoculations and N‐rich wool pellet as ecologically sound alternatives to N fertilizers. In a pot experiment, we investigated the effect of Azotobacter vinelandii, the Trichoderma harzianum T34, and wool pellet, individually and in combination, on the growth and nitrate uptake of the test plants, as well as on the biological activity and permanganate‐oxidizable carbon of the sandy soil with low organic matter content. The combination of T. harzianum + wool pellet showed the highest biological activity and permanganate‐oxidizable carbon content, while the untreated control plants exhibited the lowest values. The treatment combination of wool pellet and A. vinelandii exhibited the highest nitrate uptake by plants. Measuring the concentration of photosynthetic pigments, net photosynthesis, transpiration rate, stomatal conductance, and total dry biomass, we found that the treatments led to a significant improvement in the photosynthetic intensity of lettuce plants. These results suggest that wool pellet served as a significant source of N and that their biological activity plays a key role in improving plant parameters. Moreover, the combination of microbial inoculants and wool pellet effectively increases N use efficiency in plant growth.
The archaeology of sacred womens’ business in Australia: a Holocene history from the Central Queensland Highlands
Authors: Ponomareva Irina A. , Hatte Liz , Kemp Justine , Wallace Marie , McLennan Col 
Published: June 2024

ABSTRACTThis paper provides the initial chronological framework for an Australian Aboriginal women's sacred area, based on the first absolute ages obtained through luminescence dating. The Thirteen Mile Creek site of the Avon Downs women's sacred area provides evidence for various aspects of women's lives, including lithic raw material extraction and lithic artefact production from ∼7000 years to recent times. It is the first dated Aboriginal women's sacred area in Australia. The successful use of single grain luminescence on a colluvial mantle suggests the potential to extend cultural histories in tropical hillslopes to the middle Holocene. Our preliminary study of the site raises awareness of the challenges of protecting women's sacred sites from mining and development and highlights the importance of preserving Aboriginal sacred sites for future generations.
Levamisole Based Co(II) Single‐Ion Magnet
Authors: Biswas Soumava , Havlicek Lubomir , Nemec Ivan , Salitros Ivan , Mandal Leena , Neugebauer Petr , Kuppusamy Senthil Kumar , Ruben Mario 
Published: June 2024

AbstractA new Co(II) complex, [Co(NCS)2(L)2] (1) has been synthesized based on levamisole (L) as a new ligand. Single‐crystal X‐ray diffraction analyses confirm that the Co(II) ion is having a distorted tetrahedral coordination geometry in the complex. Notably strong intramolecular S⋅⋅⋅S and S⋅⋅⋅N interactions has been confirmed by employing Quantum Theory of Atoms in Molecules (QTAIM). These intramolecular interactions occur among the sulfur and nitrogen atoms of the levamisole ligands and also the nitrogen atoms of the thiocyanate. Direct current (dc) magnetic analyses reveal presence of zero field splitting (ZFS) and large magnetic anisotropy on Co(II). Detailed ab initio ligand field theory calculations quantitatively predicted the magnitude of ZFS. Prominent field‐induced single‐ion magnet (SIM) behavior was observed for 1 from dynamic magnetization measurements. Slow magnetic relaxation follows an Orbach mechanism with the effective energy barrier Ueff=29.6 (7) K and relaxation time τo=1.4 (4)×10−9 s.
Clinical anatomy of the coronary venous system and relevance to retrograde cardioplegia and cardiac electrophysiological interventions
Authors: Kesieme Emeka Blessius , Buchan Keith Gunn 
Published: June 2024

AbstractAnomalies of coronary venous system, the valve of the coronary sinus (Thebesian valve) and other cardiac malformations may make interventions through the coronary sinus difficult. These variants may pose a challenge in cannulating the coronary sinus for retrograde cardioplegia and for interventions performed through the coronary sinus by cardiac electrophysiologist/interventional cardiologist. Retrograde cardioplegia is an established method of myocardial protection with advantages, indications, and complications. A good knowledge of the anatomy of the coronary sinus and its variants is important in understanding the difficulties encountered while cannulating the coronary sinus for the delivery of retrograde cardioplegia, cardiac resynchronization therapy, treatment of arrhythmias, and percutaneous mitral valve annuloplasty.
Chemical Composition of Achillea millefolium L. and Their Anti‐Inflammatory Activity
Authors: Huang Xinge , Xu Nannan , Liu Zhitao , Li Hongliang , Lu Hui , Li Jun 
Published: June 2024

AbstractA new monoterpene, (−)‐10‐hydroxydihydroactinidiolide (1), along with two known monoterpenes, loliolide (2) and (+)‐isololiolide (3), three known megastigmanes, 3α‐hydroxy‐5β,6β‐epoxy‐β‐ionone (4), 3α‐hydroxy‐5α,6α‐epoxy‐β‐ionone (5), and (+)‐dehydrovomifoliol (6), a eudesmane‐type sesquiterpene, 4α‐hydroxy‐4β‐methyldihydrocostol (7), a monoterpene, 8‐hydroxycarvotanacetone (8), two flavonoids, chrysoeriol (9) and apigenin (10), and a phenylpropanoid, 3‐(4‐hydroxyphenyl)‐1‐propanol (11), were isolated from the whole plant of Achillea millefolium. The structure of compound 1 was identified according to spectroscopic data of HRMS and NMR, and its absolute configuration was assigned by 13C NMR calculations with DP4+ probability analyses and ECD calculations. The absolute configuration of compound 6 was determined by ECD calculations. Compounds 3, 6, 9 and 10 could dose‐dependently inhibit the NO release in LPS‐induced RAW264.7 cells.
Electrochemical Non‐Directed Arene C−H Amination
Authors: Stewart Griffin , Rapala Chris , Malapit Christian A. 
Published: June 2024

AbstractElectrosynthesis represents a dynamic field in organic chemistry for the development of important and selective reactions. Among the most interesting electrosynthetic transformations is the non‐directed arene C−H amination. Despite increasing reports, the quest for a non‐directed electrochemical arene C−H amination capable of accommodating a wide range of arenes and amines with high site‐selectivity remains ongoing. Non‐directed electrochemical C−H amination presents a metal‐free, mild approach for synthesizing complex aminated compounds of interest in pharmaceuticals and natural products. This concept aims to introduce the concept of non‐directed electrochemical C−H amination and provide an overview of the recent advances in the field as well as the current limitations and potential directions.
AIM2 inflammasome regulated by the IFN‐γ/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease
Authors: Zhao Yue , Liang Bin , Sheng Shuyang , Wang Chen , Jin Bingyu , Zhang Xiaokang , Cheng Yating , Shen Changxin , Zheng Fang 
Published: June 2024

AbstractBackgroundNumerous studies have demonstrated that Absent in Melanoma 2 (AIM2) is upregulated in aortic plaques, especially in Vascular Smooth Muscle Cells in Coronary Artery Disease (CAD), and is related to inflammasome‐induced inflammation. However, the underlying mechanism of this phenomenon and the role of AIM2 in atherosclerosis remained unclear.MethodsThis study enrolled 133 CAD patients and 123 controls. We isolated Peripheral Blood Leukocytes (PBLs) and the mRNA expression of AIM2 inflammasome and its downstream genes (ASC, Caspase‐1, IL‐1β, and IL‐18) were detected by real‐time quantitative PCR (qPCR). We assessed correlations between AIM2 expressions and clinical characteristics by multiple linear regression and spearman's correlation. The THP‐1 cells cultured in poly(dA:dT), A151, interferon‐gamma (IFN‐γ), AG490, or JC2‐11. And then the mRNA and protein levels of AIM2, ASC, Caspase‐1, IL‐1β, IL‐18, GSDMD, and STAT1 were analyzed by qPCR and Western blot analysis, respectively. The migration and adhesive capacity of THP‐1 cells was assessed using an inverted microscope and an inverted fluorescence microscope, respectively.ResultsIn this study, we found that expressions of components of AIM2 inflammasome and its downstream genes (ASC, Caspase‐1, IL‐1β, and IL‐18), were all increased in PBLs of CAD patients, which indicated the inflammasome activation. AIM2 inflammasome activation further induced pyroptosis, and stimulated migration and adhesion in monocyte cell lines, which was regulated by IFN‐γ probably through JAK2/STAT1 pathway. In addition, AIM2 expressions were positively correlated with systemic inflammatory indicators as an independent risk factor for CAD.ConclusionsIn conclusion, increased AIM2 expression, induced by the IFN‐γ/JAK2/STAT1 signal, orientates monocytes to inflammatory status or even pyroptosis through AIM2 inflammasome activation, which is involved in the development of CAD.
Gold/cobalt ferrite nanocomposite as a potential agent for photothermal therapy
Authors: Motorzhina Anna V. , Pshenichnikov Stanislav E. , Anikin Anton A. , Belyaev Victor K. , Yakunin Alexander N. , Zarkov Sergey V. , Tuchin Valery V. , Jovanović Sonja , Sangregorio Claudio , Rodionova Valeria V. , Panina Larissa V. , Levada Kateryna V. 
Published: June 2024

AbstractThe study encompasses an investigation of optical, photothermal and biocompatibility properties of a composite consisting of golden cores surrounded by superparamagnetic CoFe2O4 nanoparticles. Accompanied with the experiment, the computational modeling reveals that each adjusted magnetic nanoparticle redshifts the plasmon resonance frequency in gold and nonlinearly increases the extinction cross‐section at ~800 nm. The concentration dependent photothermal study demonstrates a temperature increase of 8.2 K and the photothermal conversion efficiency of 51% for the 100 μg/mL aqueous solution of the composite nanoparticles, when subjected to a laser power of 0.5 W at 815 nm. During an in vitro photothermal therapy, a portion of the composite nanoparticles, initially seeded at this concentration, remained associated with the cells after washing. These retained nanoparticles effectively heated the cell culture medium, resulting in a 22% reduction in cell viability after 15 min of the treatment. The composite features a potential in multimodal magneto‐plasmonic therapies.
Including transgender populations in mathematical models for HIV treatment and prevention: current barriers and policy implications
Authors: Tordoff Diana M. , Restar Arjee , Minalga Brian , Fernandez Atlas , Dimitrov Dobromir , Duerr Ann ,   the Seattle Trans and Nonbinary Sexual Health (STARS) Advisory Board
Published: June 2024

AbstractIntroductionMathematical models of HIV have been uniquely important in directing and evaluating HIV policy. Transgender and nonbinary people are disproportionately impacted by HIV; however, few mathematical models of HIV transmission have been published that are inclusive of transgender and nonbinary populations. This commentary discusses current structural challenges to developing robust and accurate trans‐inclusive models and identifies opportunities for future research and policy, with a focus on examples from the United States.DiscussionAs of April 2024, only seven published mathematical models of HIV transmission include transgender people. Existing models have several notable limitations and biases that limit their utility for informing public health intervention. Notably, no models include transgender men or nonbinary individuals, despite these populations being disproportionately impacted by HIV relative to cisgender populations. In addition, existing mathematical models of HIV transmission do not accurately represent the sexual network of transgender people. Data availability and quality remain a significant barrier to the development of accurate trans‐inclusive mathematical models of HIV. Using a community‐engaged approach, we developed a modelling framework that addresses the limitations of existing model and to highlight how data availability and quality limit the utility of mathematical models for transgender populations.ConclusionsModelling is an important tool for HIV prevention planning and a key step towards informing public health interventions, programming and policies for transgender populations. Our modelling framework underscores the importance of accurate trans‐inclusive data collection methodologies, since the relevance of these analyses for informing public health decision‐making is strongly dependent on the validity of the model parameterization and calibration targets. Adopting gender‐inclusive and gender‐specific approaches starting from the development and data collection stages of research can provide insights into how interventions, programming and policies can distinguish unique health needs across all gender groups. Moreover, in light of the data structure limitations, designing longitudinal surveillance data systems and probability samples will be critical to fill key research gaps, highlight progress and provide additional rigour to the current evidence. Investments and initiatives like Ending the HIV Epidemic in the United States can be further expanded and are highly needed to prioritize and value transgender populations across funding structures, goals and outcome measures.