bluuebunny/crossref_metadata_2025_split huggingface dataset:
Erectile dysfunction in psychiatric patients
Authors: Ladea M. , Bran M. , Barbu C.M. , Sarpe M.C. 
Published: May 2011

IntroductionErectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for sexual activity.ObjectivesED is a common condition in psychiatric patients, which can modify their quality of life.AimsThe aim of this study is to assess the prevalence and the severity of ED in psychiatric patients.MethodsThis naturalistic, observational study was conducted during a six months period. The International Index of Erectile Function (IIEF) 15-item questionnaire was used to assess 144 male inpatients with different psychiatric disorders. IIEF is a brief, cross-culturally valid, self-administered scale for detecting treatment-related changes in patients with erectile dysfunction and addresses the relevant domains of male sexual function: erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction. The patients were analyzed by age, psychiatric diagnosis, medication, IIEF scores at admission.ResultsThen mean age was 36.4 years. The lot included 44 patients with Psychotic Disorders, 68 with Mood Disorders, 21 with Alcohol Dependence, 11 with Personality Disorders. Severe ED was registered in 38% of investigated patients, which determined abandon of sexual attempts in 57% of cases; 12% had moderate ED, 15% had mild to moderate ED, 18% had mild ED and 17% had normal sexual function. No orgasm was reported in 32% of patients and 37% had no sexual desire. Under treatment with antipsychotic medication 78% had severe or moderate ED.ConclusionsSevere ED was correlated with age, also being seen in young patients. ED was correlated with depression, schizophrenia and antipsychotic medication.
Depression impact on the sexual desire
Authors: Lourenço M. , Azevedo L.P. , Gouveia J.L. 
Published: May 2011

IntroductionDepression as a pathology and the side effects of pharmacology therapy have been pointed proven to be as responsible for the lack of sexual desire. Among the drugs used in the treatment of depression, anti-depressives are the ones mostly connected to sexual dysfunction.Aims /objectivesTo study the relationship between depression and its impact on the sexual desire in psychiatric patients.MethodsThe chosen sample is composed of 89 subjects, 73 females and 16 males, with ages ranging from 21 to 70 years, who present with depressive symptomatology (mild to moderate symptomatology (MMS) and severe symptomatology (SS).To each patient 3 instruments were applied:
1)Questionnaire used to collect demographic and clinical data from the sample;2)Instrument of estimation of the depression degree (BDI - Beck Depression Inventory);3)Instrument of valuation of the sexual desire (SDS - Sexual Desire Scale).ResultsDepression average value obtained with BDI was 25.58 (SD = 11.86). The majority was satisfied with their marital relationship (72.7% and 52.9%, respectively), and the group with most sexual damaged (actual sexual performance regarding sexual desire) being the one with severe depression (54.5% versus 82.4%, respectively). Regarding total SDS value, the group with MMD present with higher levels of sexual desire (M = 54.93; DP = 14.56) than the group with SD (M = 41.82; DP = 11.86).ConclusionsThis study presents an exploratory character and the obtained results revealed that depressive symptomatology severity is directly related with sexual desire, by saying the higher the depression's severity is the lower sexual desire will be.
Reciprocal interaction between sexuality and personality: parallel assessment of patients with QSAF- 2009 and MCMI-III
Authors: Pirkalani K.K. , Talaee Rad Z. 
Published: May 2011

ObjectiveTo evaluate mutual interaction between sexuality and personality we tried to study 111 patients with QSAF 2009 and MCMI-III.MethodsHundred and eleven consecutive patients with sexual problems (76) or personality disorders (35) were examined with two tests. Only volunteer personality disorder patients were enrolled to this trial. The results were compared with 325 examinees evaluated with QSAF and 1600 patients evaluated with MCMI-III.ResultsAll patients with sexual problems showed at least two scores higher than 72 in their MCMI-III. This was more prominent in sexual deviations than dysfunctions. Homosexuals had higher scores in schizoid and schizotypal, pedophiles in schizoid and antisocial, voyeurs in schizoid and avoidant, masochists in dependent and self defeating personality scales …. Sexually deviated persons remain clinically latent and show themselves as alien, aloof and eccentric. Almost all deviated persons show high scores in personality disorder scales. On the contrary, only a minority of personality disorder patients show prominent sexual problems in the form of deviation. They predominantly have disturbed sexual self image, show inhibited sexual desire problems (dependent, schizoid and avoidant) personality, dyspareunia and vaginism (avoidant and schizotypal personality), spouse abuse (borderline and antisocial personality) postcoital disorders (borderline, dependent and narcissistic personality) and extramarital relationship in a series of disorders including histrionic personality …. as studied by the QSAF 2009 which evaluates 64 sexual scales.ConclusionEvaluation of personality disordered patients in regard to sexuality and vice versa is essential for better understanding the pathogenesis of each disease and helps in smoother treatments.
Questionnaire on sexual attitude and function 2009: a novel clinical and epidemiological computer based tool
Authors: Pirkalani K.K. , Talaee Rad Z. 
Published: May 2011

ObjectiveTo study sexual problems of our patients and standardizing it for patients with or without religious and cultural restrains we developed a questionnaire with 240 phrases that were extracted from a pool of 1400 sentences addressing sexual problems. Sixty four scales under four headings (sexual general characteristics, deviations, dysfunctions and psychodynamic syndromes) (16 items each) were evaluated based on criteria of DSM-IV and ICD 10. Five validity scales (honesty, desirability, debasement, guilt feeling and overall validity) were also used for better assessment.MethodsA total of 1300 patients in the four variants of the test were evaluated during a time span of 7 years. The questions were presented to examinees at 8th. Grade and higher in a calm environment and the results were evaluated by a computer software specifically developed for this purpose.ResultsThe last version of the test was completed by 734 patients with excellent compliance. It was of nice politeness and comprehensiveness. For almost all scales the sensitivity and specificity were around 85 and 92% respectively.ConclusionWe conclude that QSAF 2009 is an excellent tool both in clinics (diagnosis and follow up) and epidemiology with high sensitivity and specificity. It has also application in cross cultural studies, medico - legal issues and medical documentation. It prevents face to face interviews, breaks patients’ resistance and is less time consuming than scheduled interviews.
The prevalence of sexual dysfunctions in infertile women
Authors: Tayebi N. 
Published: May 2011

ObjectiveSexuality is an important and integral part of every woman's life. The aim of this study was to assess the degree of sexual dysfunction among infertile women and its correlation with age, duration of marriage and etiology of infertility in women.Materials and methods300 infertile women who were referred to IVF center for management of their infertility problem involved in this study after informed consent. They were asked to fill a questionnaire that contained three parts of demographic, infertility and sexual function items. Distribution of sexual dysfunction and its relationship to infertility and marriage duration were analyzed through SPSS software.ResultsThe most common sexual dysfunction was orgasm disorder (83.76%) and the rate of sexual desire disorder, dyspareunia and vaginismus were 80.7%, 67.7% and 76.7% respectively. More than 50% of cases mentioned decreased frequency of coitus after diagnosis of infertility. Vaginismus and dyspareunia were more common in 20–24 years age group.ConclusionAccording to the high rate of sexual dysfunction in this study and almost the same rate in other studies, gynecologists should pay more attention to this important issue and encourage the patients to have an evaluation by a psychiatrist or psychologist.
Relaibility and validity of the Chinese translation of insomnia severity index (C-ISI) in Chinese patients with insomnia
Authors: Badiee Aval Baghyahi S. , Torabi S. , Gao Y. , Cao K.G. , Badiee Aval Baghsyahi H.R. 
Published: May 2011

IntroductionThe Insomnia Severity Index (ISI) is a Questionnaire to screen insomnia in clinics;so,it has been translated into many languages.ObjectivesTo determine the relaibility and validity of the Chinese Translation of Insomnia Severity Index(C-ISI) in patients with Insomnia and compare it with Chinese version of Pittsburgh Sleep Quality Index(C-PSQI).AimsTo prove the relaibility and validity of C-ISI for using it in chinese speakers.MethodEnglish version ISI was translated into Chinese base on standard guidelines then Chinese version was filled in 83 patients with insomnia as a clinical group and 45 persons without sleep complain as the control group by themselves in Neuropsychiatery Department of DongzhiMen hospital. For finding Test-Retest reliability they refilled ISI questionnaire 2 weeks later.ResultsCronbach-α coefficient of C-ISI for the clinical group, control group and both of them was 0.72, 0.75 and 0.91 respectively. The C-ISI component and total scores in test were significantly correlated with their related components and total scores in re-test (P < 0.05). Mean Ranks for All C-ISI components, total score were significantly higher in clinical group than control group that presents low sleep quality in clinical group. There are Significant correlations between C-ISI component and total scores and C-PSQI components and Total scores in related Items.ConclusionsC-ISI has acceptable reliability and good sensitivity for assessing insomnia patients; besides, C-ISI can evaluate the insomnia patients similar to the PSQI-C so it can be used as a good scale to measure sleep quality in Chinese speakers.
Effect of acupuncture as a complementary medicine in treating insomnia
Authors: Badieeavalbaghyahi S. , Zhang X. , Torabi S. , Badieeavalbaghsyahi H. 
Published: May 2011

IntroductionAcupuncture, as complementary medicine, has been used since many years ago in china and many researches have proved its effect separately or combined with other treatment methods.ObjectivesTo compare therapeutic effects of Acupuncture plus estazolam and Cognitive - Behavioral Therapy plus estazolam on insomnia.AimsTo determine the efficacy of acupuncture as complementary medicine in treating insomnia.Method64 insomnia patients were randomly divided into an acupuncture group and a behavioral group, 30 cases in acupuncture group and 18 cases in behavioral group completed research. The acupuncture group was treated by administration oral estazolam before sleeping each day and needling, three times a week, the behavioral group received Stimulus control as a Cognitive - Behavioral Therapy plus oral estazolam before sleeping each day. Treatment course was 3 weeks. The insomnia severity index (ISI) scores before and after treatment were observed in the both groups.ResultsThe total effective rate was 86.7% in the acupuncture group and 50% in the behavioral group with statistically significant difference (P < 0.05). The cured rate of 30% in the acupuncture group was significantly higher than 16.7% in the behavioral group (both P < 0.05).ConclusionsThe therapeutic effect of Acupuncture as a complementary medicine on insomnia is better than stimulus therapy as a Cognitive - Behavioral Therapy.
Is disturbed sleep predictive for later “burnout” - a 20 year perspective
Authors: Hetta J. , Mallon L. , Broman J.-E. 
Published: May 2011

The aim was to examine if sleeping difficulties in year 1983 predicted “burnout” in year 2003.MethodsIn 1983: 1.687 subjects, aged 30–44 years, answered a sleep questionnaire (USI).In 2003: In a follow-up, 1.192 subjects, aged 50–64 years, answered the same sleep questionnaire. Subjects were asked about difficulties initiating sleep (DIS) and difficulties maintaining sleep (DMS), and not being rested by sleep (NRS). The questions were answered on a five-point scale(1 = no problems,2 = minor problems,3 = moderate problems,4 = severe problems,5 = very severe problems).At least severe problems (scores 4 and 5) were considered to be a complaint. Insomnia was defined as having at least one complaint. In year 2003 questions about health included a statement about being “burnout”.ResultsIn year 2003 “burnout” was reported by 7,3% of women, and in 3,9% in men.In a logistic regression we examined the risk for “burnout” in relation to DIS, DMS and NRS at baseline. For women DMS (OR 2,8 CI 1,1-8,0) and NRS (OR 3,3 CI 1,2-9.3) were significant. DIS which was the only significant association for men (OR 7,3 CI 2,0-25,3).ConclusionSleep complaints are predictive for a “burnout”-condition later in life.
An evaluation study of the Epworth sleepiness scale adapted for children and adolescents: a tool for case finding of pediatric excessive daytime sleepiness (EDS)
Authors: Lecendreux M. , Gamble H. , Sanchez-Garrido L. , Giordanella J.-P. , Konofal E. 
Published: May 2011

Child and adolescent sleepiness is an important public health issue with potentially serious consequences on attention, learning, behaviour, and quality of life. For some individuals, sleepiness may be due to a sleep disorder which requires clinical investigation and subsequent treatment. A reliable measure of child and adolescent sleepiness is needed and a version of the Epworth Sleepiness Scale has been adapted for use in child and adolescent populations.The adapted Epworth Scale is a questionnaire which aims to identify the chance of falling asleep in 10 different situtations. This questionnaire is normally used in a clinical context as a diagnostic tool. The objective of this study was to investigate whether the adapted Epworth Scale could be used to screen for sleep disorders in a similar manner to the adult scale. This presentation describes a validation study of the adapted Epworth Scale in a population of college students. 9,005 Parisian college students (50.4% female) completed an on-line questionnaire. The mean age was 12.7 years (sd = 1.35). The response rate was greater than 95% for each item of the adapted Epworth score. The mean score was 8.6 / 30 (sd = 4.62).We suggest that the adapted Epworth Scale could be used as a tool for case finding of excessive daytime sleepiness in schools. If the adapted scale is to be used for this purpose, subjects with high scores should be offered investigation to exclude underlying sleep disorders such as narcolepsy, primary hypersomnia or ADHD.
One night sleep restriction impairs the cortical oxygenation responses
Authors: Miyata S. , Noda A. , Ito M. , Iwamoto K. , Ozaki N. 
Published: May 2011

IntroductionSleep restriction has adverse effects on performance and neurobehavioral function. However, the mechanism of impaired performance and neurobehavioral function has not been studied yet.ObjectivesWe examined the effect of insufficient sleep on cerebral blood flow and cognitive function in 8 healthy adults (mean age 22.4 years).MethodsAll participants were in bed for 8 h (sufficient sleep), and for < 4 h (insufficient sleep). The oxyhemoglobin (oxyHb) level by a word fluency task was measured with a near-infrared spectroscopy recorder on the morning following sufficient and insufficient sleep periods. Wisconsin card sorting test (WCST), continuous performance test (CPT) and N-back test were evaluated on the same days.ResultsThe peak oxyHb level was significantly lower in the left and right frontal lobes after insufficient sleep than after sufficient sleep (left: 0.25 ± 0.10 vs. 0.70 ± 0.29 mmol, P < 0.05; right: 0.23 ± 0.13 vs. 0.73 ± 0.22 mmol, P < 0.05). There was no significant difference in the number of words generated during the word fluency task between sufficient and insufficient sleep states. The percentage of correct responses on CPT after insufficient sleep was significantly lower than that after sufficient sleep (86.6 ± 10.2 vs. 96.0 ± 4.9%, P < 0.05). The reaction time of WCST was significantly longer after insufficient sleep than after sufficient sleep (76.6 ± 13.4 vs. 70.6 ± 16.2 sec, P < 0.05).ConclusionsOne night sleep restriction decreased the concentration changes of oxyHb in brain tissue, leading to impaired cognitive function.
Effect of melatonin on insomnia in patients with hyperthymic temperament: An open clinical trial
Authors: Nastase S. , Ivanovici D. , Nastase L. 
Published: May 2011

IntroductionThe link among melatonin levels, pineal function, insomnia and affective spectrum is strengthened by epidemiologic and chronobiological evidence. From the affective spectrum, we selected the hyperthymic temperament, which is characterized by exuberant, upbeat, overenergetic, and overconfident lifelong traits.ObjectivesWe examined whether insomnia in persons with hyperthymic temperament responds particularly to the treatment with melatonin, in comparison with the euthymics patients with insomnia.MethodWe ran an open label study on 20 subjects. None suffered from depression, mania or hypomania.The study population comprised two groups: one group with patients with insomnia whose temperament presented hyperthymic traits (10 subjects) and the other group with euthymic adults, (10 subjects).The Athens Insomnia Scale 5-item version (AIS-5) was administered to the two groups before and after the treatment with melatonin. The AIS is a self-assessment psychometric instrument designed for quantifying sleep difficulty based on the ICD-10 criteria.The patients took a single daily dose of 5 mg of melatonin with 30 minutes before bedtime. Using the AIS-5, we have assessed sleep at baseline and after 4 weeks of treatment. SPSS version 11 was used for statistical analysis.ResultsAfter 4 weeks of melatonin therapy (5 mg/day), the comparison of the two groups showed that melatonin is more effective in the insomniacs with hyperthymic temperament comparative with the euthymic patients.ConclusionMelatonin has shown promising results in the treatment of insomnia in patients with hypertimic temperament. Further studies are necessary to better investigate the role of melatonin on insomnia in bipolar spectrum.
Sleep quality and its correlation to general health status in health care students
Authors: Sahraian A. , Javadpour A. , Mani A. 
Published: May 2011

IntroductionSleep-wake cycle is one of human biological rhythm highly correlated to well being and general health status.Poor sleep quality, sleep disruption and changes in regular Sleep-wake pattern may cause physical and psychological burden such as impairment in job performance, decreased work efficiency and learning disability.ObjectiveHealth care students trained in medical, nursing and midwifery fields is a population who are at great risk to develop sleep disruption and its subsequent physical and mental morbidity.AimThe aim of this study was to describe how sleep quality correlated to general health status among 280 health care students.Methods280 health care students studying in health related fields participated in this cross section study. Pittsburg sleep quality index (PSQI), sleep- wake questionnaire and the general health questionnaire (GHQ) administered to gather data describing sleep quality, sleep wake disruption and the general health status.ResultsPreliminary results showed that 61.4% of subjects defined as poor sleeper. In further co relational analysis there was a significant correlation between sleep quality and general health status (r = .6, p = . 000, n = 280). Regression analysis showed that number of nights with sleep disruption due to shift work or academic needs was a strong predictor for both poor sleep quality and general health status.ConclusionIn conclusion, Sleep disruption due to shift work or other academic demands is a predictor for poor sleep and its subsequent mental health morbidity, which should be considered as a part of mental health policy for health related college students.
The contribution of individual and combined common non-communicable diseases to poor sleep quality: The japanese civil servants study
Authors: Sekine M. , Tatsuse T. 
Published: May 2011

IntroductionSome of common non-communicable diseases deteriorate sleep quality, which worsens the disease itself. This study aims to evaluate
(1)whether common non-communicable diseases are associated with poor sleep quality and(2)whether the combination of such diseases increase the possibility of poor sleep quality.MethodsThe subjects were civil servants in local government in Japan. A questionnaire survey was conducted in January 2003. Altogether 4272 subjects responded (response rate: 79.2%). Subjects were asked about whether they were diagnosed as having common non-communicable diseases (i.e. heart disease, cerebrovascular disease, hypertension, hyperlipidemia, diabetes, bronchial asthma, gastroduodenal ulcer, mental disorders, and low back pain). Overweight was evaluated by using BMI. Poor sleep quality was evaluated using Pittsburgh Sleep Quality Index (PSQI).ResultsThe age- and sex-adjusted odds ratio (OR) for poor sleep quality was higher among patients with heart disease, cerebrovascular disease, hypertension, hyperlipidemia, diabetes, bronchial asthma, gastroduodenal ulcer, mental disorders, low back pain, and obesity but the associations were not necessarily significant. However, the combination of such common non-communicable diseases significantly increased the possibility of poor sleep quality, with a dose-response relationship.ConclusionAlthough individual common non-communicable diseases may not necessarily cause poor sleep quality, the combination of these may increase the prevalence of poor sleep quality. Clinician should think that patients may have poor sleep quality if they have several non-communicable diseases.
Long-term efficacy and safety of zolpidem extended-release 12.5 mg, in old patients with chronic primary insomnia: a randomized, double-blind, placebo-controlled, parallel-group, multicenter study
Authors: Zarra J. , Schmidt L. 
Published: May 2011

ObjectiveTo evaluate long-term efficacy and safety of zolpidem extended-release, in old patients for chronic primary insomnia.DesignMulticenter, randomized, double-blind, placebo-controlled, parallel-group.MethodPopulation: Outpatient with aged more of 65 years. Diagnosis: DSM-IV criteria for chronic primary insomnia; Treatment: Single-dose zolpidem extended-release 12.5 mg (n = 128) or placebo (n = 127), self-administered every night.ResultsPatient's Global Impression (PGI) and Clinical Global Impression-Improvement (CGI-I) were assessed every 4 weeks up to six month. Patient Morning Questionnaire (PMQ), recorded daily, assessed subjective sleep measures-sleep onset latency (SOL), total sleep time (TST), number of awakenings (NAW), wake time after sleep onset (WASO), and quality of sleep (QOS)-and next-day functioning. Zolpidem extended-release also was statistically significantly superior to placebo at every time point for PGI (Items 1–4) and CGI-I (P < 0.0001, rank score), TST, WASO, QOS (P < 0.0001), and SOL (P < or = 0.0014); NAW (Months 2–6; P < 0.0001). Sustained improvement (P < 0.0001, all time points) was observed in morning sleepiness and ability to concentrate (P = 0.0014, month 6) with zolpidem extended-release compared with placebo. Most frequent adverse events for zolpidem extended-release were headache, anxiety and somnolence to the morning. No rebound effect was observed during the first 3 nights of discontinuation.ConclusionsThese findings establish the efficacy of dosing of zolpidem extended-release 12.5 mg for up to 6 months. Treatment provided sustained and significant improvements in sleep onset and maintenance and also improved next-day concentration and morning sleepiness.