bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review of Penile Prosthetic Reservoir: Complications and Presentation of a Modified Reservoir Placement Technique
Authors: Levine Laurence A. , Hoeh Michael P. 
Published: June 2012

ABSTRACT

Introduction
Multiple modifications have been made to the inflatable penile prosthesis (IPP) since its inception in the 1970s. These modifications have made reservoir-related mechanical malfunctions highly unlikely in current IPP models. Although these complications are rare, it would be incumbent upon the implanting surgeon to be aware of these potential complications, how they present, how they are best treated, and how to prevent them from occurring.

Aims
The aim of this article was to present our experience with complications associated with penile prosthesis reservoirs, perform a review of the literature regarding reservoir-related complications, and present our modified technique to place the reservoir into the space of Retzius.

Main Outcome Measures
Reservoir-related complications including inguinal herniation, erosion into bladder or bowel, intraperitoneal reservoir placement with subsequent visceral injury, vascular injury, autoinflation, and infection.

Methods
We retrospectively reviewed our experience with penile prosthesis reservoir complications or procedures requiring an alternative implantation approach at our center over the past 10 years where over 400 devices were implanted. We also review reservoir-related complications published in the English literature since the 1980s.

Results
While exceedingly rare, reservoir complications do occur. Six cases from our institution are presented including one reservoir herniation, one postoperative direct inguinal hernia, one bladder laceration during revision surgery, one ectopic reservoir placement due to morbid obesity, one iliac vein compression syndrome, and one vascular laceration during reservoir revision. Reported reservoir complications include inguinal herniation, erosion into the bladder or bowel, intraperitoneal reservoir placement with subsequent injury to the ureter or bowel, vascular injury, autoinflation, and infection.

Conclusion
Penile prosthesis reservoirs rarely fail mechanically but are associated with a variety of complications or may require alternate implantation technique. In our experience, the Jorgensen scissors technique allows safe entry into the space of Retzius with diminished risk of hernia as well as vascular, bladder, or bowel injury.
Is Testosterone Treatment Good for the Prostate? Study of Safety During Long-Term Treatment
Authors: Feneley Mark R. , Carruthers Malcolm 
Published: June 2012

ABSTRACT

Introduction
For men with androgen deficiency on testosterone replacement therapy (TRT), clinical concern relates to the development of prostate cancer (PCa).

Aim
An updated audit of prostate safety from the UK Androgen Study was carried out to analyze the incidence of PCa during long-term TRT.

Main Outcome Measures
Diagnosis of PCa in men receiving TRT, by serum prostate-specific antigen (PSA) testing and digital rectal examination (DRE), and its relation to different testosterone preparations.

Methods
One thousand three hundred sixty-five men aged 28–87 (mean 55) years with symptomatic androgen deficiency and receiving TRT have been monitored for up to 20 years. All patients were prescreened for PCa by DRE and PSA along with endocrine, biochemical, hematological, and urinary profiles at baseline and every 6 months. Abnormal findings or rising PSA were investigated by transrectal ultrasound and prostate biopsy. The data were compared for the four different testosterone preparations used in TRT, including pellet implants, Restandol, mesterolone, and Testogel.

Results
Fourteen new cases of PCa were diagnosed at one case per 212 years treatment, after 2,966 man-years of treatment (one case per 212 years). Time to diagnosis ranged from 1 to 12 years (mean 6.3 years). All tumors were clinically localized and suitable for potentially curative treatment. Initiating testosterone treatment had no statistically significant effect on total PSA, free PSA or free/total PSA ratio, and any initial PSA change had no predictive relationship to subsequent diagnosis of cancer.

Conclusions
The incidence of PCa during long-term TRT was equivalent to that expected in the general population. This study adds to the considerable weight of evidence that with proper clinical monitoring, testosterone treatment is safe for the prostate and improves early detection of PCa. Testosterone treatment with regular monitoring of the prostate may be safer for the individual than any alternative without surveillance.
The rise of the constitutional regulatory state in Colombia: The case of water governance
Authors: Urueña Rene 
Published: June 2012

AbstractThis article interprets the regulatory state in Colombia as the result of a dialectic process between transnational knowledge and domestic politics, which influence, transform, and inspire each other. Such a process results in an interesting constitutional variant of the regulatory state, in which neo‐constitutionalism becomes a counterbalance to the unchecked expansion of neo‐liberal regulatory practices. I, therefore, distinguish between neoliberal and constitutional regulatory states. As a result of neo‐constitutionalism, the domestic judiciary is empowered, and becomes a crucial actor to understand both the specific traits of this regulatory experience, and its interaction with global centers of power.
Antimicrobial Activity of Whey Protein Isolate Edible Films with Essential Oils against Food Spoilers and Foodborne Pathogens
Authors: Fernández‐Pan Idoya , Royo Maite , Ignacio Maté Juan 
Published: June 2012

Abstract:  The use of antimicrobial edible film is proposed as a means of improving food safety and extending the shelf‐life of food systems by controlling the release of antimicrobials on food surfaces. In this work we first selected and studied 8 different essential oils (EOs) from plants, namely, oregano, clove, tea tree, coriander, mastic thyme, laurel, rosemary, and sage as natural antimicrobials against 2 gram‐positive bacteria (Listeria innocua and Staphylococcus aureus) and 2 gram‐negative bacteria (Salmonella enteritidis and Pseudomona fragi) by using the agar disk diffusion method. EOs from oregano, clove, and tea tree produced the largest surfaces of inhibition against the growth of the 4 bacterial strains tested. Second and following the assessment of compatibility, stable antimicrobial edible films based on whey protein isolate (WPI) with increasing concentrations (0.5% to 9%) of the 8 EOs were developed and tested for antimicrobial activity against the same gram‐positive and gram‐negative bacteria. WPI‐edible films incorporating oregano or clove EO were found to have the most intense inhibitory effect of microbial growth. The bacterial strain gram‐negative P. fragi presented the less susceptibility to the effect of those films. Moreover, only the edible films based on these 2 EOs were active against all 4 studied microorganisms. On the other hand, the edible films incorporating tea tree, coriander, mastic thyme, laurel, rosemary, or sage EOs even at high concentrations (7% to 9%) did not cause any antimicrobial effect against the pathogens S. aureus or S. enteritidis.Practical Application:  Potential applications of this technology can introduce direct benefits to the food industry by improving safety and microbial product quality. The results of this research have direct application in the food industry with potential applications in various foodstuffs, including meat and poultry products where the control of spoilage bacteria such as P. fragi throughout their chilled storage or the improvement of food safety by controlling pathogens such as S. enteritidis are topics of particular interest for the industry.
Young people at risk for psychosis: case finding and sample characteristics of the Oulu Brain and Mind Study
Authors: Veijola Juha , Mäki Pirjo , Jääskeläinen Erika , Koivukangas Jenni , Moilanen Irma , Taanila Anja , Nordström Tanja , Hurtig Tuula , Kiviniemi Vesa , Mukkala Sari , Heinimaa Markus , Lindholm Päivi , Jones Peter B. , Barnett Jennifer H. , Murray Graham K. , Miettunen Jouko 
Published: June 2012

AbstractAim: Set within the general population‐based Northern Finland Birth Cohort 1986, the Oulu Brain and Mind Study aims to explore the causes and pathogenesis of psychotic illness by following young people at risk for psychosis due to having a first‐degree relative with psychotic illness or due to having experienced psychotic‐like symptoms themselves. We report the study methods and explore the relationship between these definitions of high risk for psychosis and operational criteria for a prodromal psychosis syndrome based on interview.Methods: Prospectively collected data from earlier follow‐ups of this cohort were combined with health register data to categorize subjects as those with familial risk (n = 272), symptomatic risk (n = 117), psychosis (n = 78), attention deficit hyperactivity disorder (ADHD) (n = 103) and a sample of controls (n = 193) drawn randomly from the remaining cohort. The Structured Interview for Prodromal Syndromes (SIPS) was applied to all, 295 participants together with questionnaires measuring psychosis vulnerability and schizotypal traits.Results: There were 29 (10%) current prodromal cases. Criteria for the current prodromal syndrome were fulfilled by 12% of the familial risk group and 19% of the symptomatic risk group, compared with 5% of the ADHD group and 4% of controls.Conclusion: We successfully detected young people with a prodromal psychosis syndrome although relatively few subjects deemed to be at high risk met the full operational criteria according to the SIPS interview. Combining methods from familial, clinical and psychometric high‐risk approaches provides a tractable method for studying risk of psychosis in the general population.
Borderline personality features and development of psychosis in an ‘Ultra High Risk’ (UHR) population: a case control study
Authors: Thompson Andrew , Nelson Barnaby , Bechdolf Andreas , Chanen Andrew M. , Domingues Isabel , McDougall Emma , Yung Alison R. 
Published: June 2012

AbstractAims: There is clinical uncertainty as to whether borderline personality disorder (BPD) traits in those with an ‘at risk mental state’ have an effect on the risk of ‘transition’ to psychosis. We aimed to investigate the relationship between baseline BPD features, risk of transition and type of psychotic disorder experienced.Method: This is a case‐control study of ‘Ultra High Risk’ (UHR) for psychosis patients treated at the clinic, between 2004 and 2007. ‘Cases’ were UHR individuals who made the ‘transition’ to full threshold psychotic disorder within 24 months; ‘Control’ group was a matched UHR sample who had not developed a psychotic disorder at 24 months. Individuals were matched on time of entry to the clinic, age and gender. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM‐IV) BPD features were assessed from clinical assessments using a structured instrument (Structured Clinical Interview for DSM‐IV Axis II Disorder for BPD (SCID‐II BPD) ). Psychosis diagnosis following transition was rated from the clinical files using the operational criteria in studies of psychotic illness (OPCRIT) computer algorithm. The number of BPD traits and number with full threshold BPD were compared in those who developed psychosis and those who did not.Results: We analysed data from 48 cases and 48 controls. There was no statistically significant difference in the rate of transition to psychosis for those with baseline full‐threshold BPD, compared with those without BPD. The number of BPD traits or number with full threshold BPD did not differ by psychosis diagnosis grouping.Conclusions: Co‐occurring BPD or BPD features does not appear to strongly influence the risk of short‐term transition to psychosis or the risk of developing a non‐affective psychotic disorder in this population.
Encyclopaedias and Genre, 1670‐1750
Authors: LOVELAND JEFF 
Published: June 2012

AbstractThis article examines genres of general encyclopaedias in western Europe from 1670 to 1750. My approach is twofold. First, by examining references to genres in discourse about encyclopaedias, I will try to determine whether consensus existed about the kinds of general encyclopaedias. Second, I will evaluate late seventeenth‐ and early eighteenth‐century claims about the kinds of encyclopaedias in light of works' contents to arrive at a similar but more dynamic classification. Finally, besides providing information about the kinds of encyclopaedias in the early modern period, this investigation is meant to cast light on the ancestry of the modern encyclopaedia.
Contrasting microbial assemblages in adjacent water masses associated with the East Australian Current
Authors: Seymour Justin R. , Doblin Martina A. , Jeffries Thomas C. , Brown Mark V. , Newton Kelly , Ralph Peter J. , Baird Mark , Mitchell James G. 
Published: June 2012

SummaryDifferent oceanographic provinces host discrete microbial assemblages that are adapted to local physicochemical conditions. We sequenced and compared the metagenomes of two microbial communities inhabiting adjacent water masses in the Tasman Sea, where the recent strengthening of the East Australian Current (EAC) has altered the ecology of coastal environments. Despite the comparable latitude of the samples, significant phylogenetic differences were apparent, including shifts in the relative frequency of matches to Cyanobacteria, Crenarchaeota and Euryarchaeota. Fine‐scale variability in the structure of SAR11, Prochlorococcus and Synechococcus populations, with more matches to ‘warm‐water’ ecotypes observed in the EAC, indicates the EAC may drive an intrusion of tropical microbes into temperate regions of the Tasman Sea. Furthermore, significant shifts in the relative importance of 17 metabolic categories indicate that the EAC prokaryotic community has different physiological properties than surrounding waters.
Ranking of healthcare programmes based on health outcome, health costs and safe delivery of care in hospital pharmacy practice
Authors: Brisseau Lionel , Bussières Jean-François , Bois Denis , Vallée Marc , Racine Marie-Claude , Bonnici André 
Published: June 2012

Abstract

Objectives
To establish a consensual and coherent ranking of healthcare programmes that involve the presence of ward-based and clinic-based clinical pharmacists, based on health outcome, health costs and safe delivery of care.

Methods
This descriptive study was derived from a structured dialogue (Delphi technique) among directors of pharmacy department. We established a quantitative profile of healthcare programmes at five sites that involved the provision of ward-based and clinic-based pharmaceutical care. A summary table of evidence established a unique quality rating per inpatient (clinic-based) or outpatient (ward-based) healthcare programme. Each director rated the perceived impact of pharmaceutical care per inpatient or outpatient healthcare programme on three fields: health outcome, health costs and safe delivery of care. They agreed by consensus on the final ranking of healthcare programmes.

Key findings
A ranking was assigned for each of the 18 healthcare programmes for outpatient care and the 17 healthcare programmes for inpatient care involving the presence of pharmacists, based on health outcome, health costs and safe delivery of care. There was a good correlation between ranking based on data from a 2007–2008 Canadian report on hospital pharmacy practice and the ranking proposed by directors of pharmacy department.

Conclusions
Given the often limited human and financial resources, managers should consider the best evidence available on a profession's impact to plan healthcare services within an organization. Data are few on ranking healthcare programmes in order to prioritize which healthcare programme would mostly benefit from the delivery of pharmaceutical care by ward-based and clinic-based pharmacists.
Personal beliefs about illness questionnaire‐revised (PBIQ‐R): Reliability and validation in a first episode sample
Authors: Birchwood Max , Jackson Chris , Brunet Kat , Holden Judith , Barton Karen 
Published: June 2012

Objective. To further develop the Personal Beliefs about Illness Questionnaire (PBIQ), which reflects current constructs of social rank theory in relation to people experiencing psychosis.Method. Drawing on extensive clinical and research experience and after consultation with other mental health professionals and service users, 17 new items were added to 12 from the original 16 PBIQ questions. These made up five theoretical constructs (entrapment, loss, social marginalization, shame, and control). A total of 150 people who had just experienced a first episode of psychosis completed the newly devised PBIQ‐R. To test the validity of its five subscales, a small sub‐sample (N= 66) for whom follow‐up data was available also completed measures of depression, insight, and other social rank appraisals.Results. All five subscales of the PBIQ‐R were found to be reliable, valid, and sensitive to change.Conclusions. Although the PBIQ‐R was not designed to produce an overall ‘personal beliefs about illness’ score, its five subscales provide a rapid and valid method to assess and measure common psychological reactions to a first episode of psychosis. It will have relevance for use in older, multiple episode samples although further validation may be needed.
Characterization of a Novel IMP-28 Metallo-β-Lactamase from a Spanish Klebsiella oxytoca Clinical Isolate
Authors: Pérez-Llarena Francisco José , Fernández Ana , Zamorano Laura , Kerff Frédéric , Beceiro Alejandro , Aracil Belén , Cercenado Emilia , Miro Elisenda , Oliver Antonio , Oteo Jesús , Navarro Ferran , Bou Germán 
Published: June 2012

ABSTRACT

An isolate of
Klebsiella oxytoca
carrying a novel IMP metallo-β-lactamase was discovered in Madrid, Spain. The
bla
IMP-28
gene is part of a chromosomally located class I integron. The IMP-28
k
cat
/

K
m

values for ampicillin, ceftazidime, and cefepime and, to a lesser extent, imipenem and meropenem, are clearly lower than those of IMP-1. The His306Gln mutation may induce important modifications of the L3 loop and thus of substrate accessibility and hydrolysis and be the main reason for this behavior.
Escherichia coli: Great Diversity around a Common Core
Authors: Moriel Danilo G. , Rosini Roberto , Seib Kate L. , Serino Laura , Pizza Mariagrazia , Rappuoli Rino 
Published: June 2012

ABSTRACT

The 2011
Escherichia coli
outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of
E. coli
and the potential for new virulent strains to emerge. The analysis of 170
E. coli
genome sequences for the presence of nine previously identified protective extraintestinal pathogenic
E. coli
antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic
E. coli
strains.

IMPORTANCE
This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic
Escherichia coli
strains.
Recurrent retroperitoneal liposarcoma in a patient with neurofibromatosis type I
Authors: Gomez Carrie K , Rosen Gerald , Mitnick Robin , Chaudhri Ali 
Published: June 2012

IntroductionLiposarcoma complicating neurofibromatosis is very rare. Only a few cases have been described until now. We present a case of recurrent dedifferentiated retroperitoneal liposarcoma in a patient with neurofibromatosis type I (NF-1).Case presentationA 47-year-old Caucasian woman with NF-1 presented to the hospital initially complaining of left lumbar pain irradiating to the anterior thigh and knee. Physical examination showed atrophy of the lower extremities bilaterally and decreased motor strength on the left lower extremity. Radiological studies demonstrated an enhancing lesion in the left paraspinal region, suggesting malignancy. The patient underwent local resection of tumour with safety margins. Pathological examination was consistent with dedifferentiated liposarcoma (DDLS) with positivity for MDM2 and CDK4 markers. No evidence of metastasis was noted on the radiological studies. The final diagnosis was DDLS, high-grade (G3), pT2bN0M0, stage III. After 6 weeks post-tumour resection, the patient experienced recurrence of malignancy. Chemotherapy with cisplatin and doxorubicin was initiated in the patient.ConclusionsLiposarcoma in the context of neurofibromatosis is very rare. To the best of our knowledge, only six cases have been reported until now in the literature. We are presenting this case to underline the possibility of recurrence in the case of retroperitoneal DDLSs despite local tumour resection. Also, although the role of chemotherapy is controversial we decided to start treatment with cisplatin and doxorubicin given the success of chemotherapy in similar case presentations.
Predictors and Prognostic Value of Myocardial Injury During Transcatheter Aortic Valve Implantation
Authors: Yong Ze Yie , Wiegerinck Esther M. A. , Boerlage-van Dijk Kirsten , Koch Karel T. , Vis Marije M. , Bouma Berto J. , Henriques José P. S. , Cocchieri Riccardo , Piek Jan J. , de Mol Bas A. J. M. , Baan Jan 
Published: June 2012

Background—
Myocardial injury is a common complication during cardiac surgery and percutaneous coronary intervention and is associated with postprocedural cardiovascular morbidity and mortality. Limited data have been reported about the occurrence of myocardial damage associated with transcatheter aortic valve implantation (TAVI). Therefore, our purpose was to investigate the incidence, predictors, and prognostic value of myocardial injury during TAVI.

Methods and Results—

We studied 119 patients (aged 81±8 years; 47 male) who had undergone a TAVI with the Medtronic-CoreValve bioprosthesis. Serum creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) levels were measured before and after the procedure.
Myocardial injury
was defined as a postprocedural increase of CK-MB and/or cTnT level >5 times the upper reference limit. After TAVI, the incidence of myocardial injury was 17%, which was independently predicted by procedural duration (in minutes) (odds ratio [OR], 1.04; 95% CI, 1.01–1.06), preprocedural β-blocker use (OR, 0.12; 95% CI, 0.03–0.45), peripheral arterial disease (OR, 6.36; 95% CI, 1.56–25.87), and prosthesis depth (in millimeters) (OR, 1.31; 95% CI, 1.08–1.59). The 30-day mortality after TAVI was 13% and was independently predicted by myocardial injury (OR, 8.54; 95% CI, 2.17–33.52), preprocedural hospitalization (OR, 9.36; 95% CI, 2.55–34.38), and left ventricular mass index (in g/m
2
) (OR, 1.02; 95% CI, 1.00–1.03).

Conclusions—
After transcatheter aortic valve implantation, serum levels of both CK-MB and cTnT increase, reflecting the occurrence of periprocedural myocardial injury. A longer procedural duration, the absence of β-blocker use, peripheral arterial disease, and a deeper prosthesis insertion are associated with myocardial injury. Together with preprocedural hospitalization and left ventricular mass, myocardial injury is an independent predictor for 30-day mortality after TAVI.