bluuebunny/crossref_metadata_2025_split huggingface dataset:
Naphthalene metabolites 1‐naphthol and 2‐naphthol [Biomonitoring Methods, 2010b]
Authors: Preuss R. , Angerer J. 
Published: January 2012

AbstractPublished in the seriesBiomonitoring Methods, Vol. 12 (2010)The article contains sections titled:General principlesEquipment, chemicals and solutionsEquipmentChemicalsSolutionsCalibration standardsSpecimen collection and sample preparationSample preparationOperational parametersOperational parameters for high performance liquid chromatographyFluorescence detectionAnalytical determinationCalibrationCalculation of the analytical resultsStandardisation and quality controlEvaluation of the methodPrecisionAccuracyDetection limit and quantification limitSources of errorDiscussion of the method
CO‐Hb Einwellenlängenmethode [Biomonitoring Methods in German language, 1983]
Authors: Pilz und I. Johann W. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 7. Lieferung, Ausgabe 1983Der Artikel enthält folgende Kapitel:ZusammenfassungGeräte, Chemikalien und LösungenGeräteChemikalienLösungenVergleichsstandardsProbenahme und ProbenaufbereitungAnalytische BestimmungKalibrierungBerechnung des AnalysenergebnissesStandardisierung der Meßergebnisse und QualitätssicherungAutomationBeurteilung des VerfahrensPräzisionRichtigkeitNachweisgrenzeDiskussion der MethodeHerstellung von HämolysatenOxyhämoglobinCO‐HämoglobinHerstellung von Kohlenmonoxid im Laboratoriumsmaßstab
Carboxyhemoglobin [Biomonitoring Methods, 1985]
Authors: Angerer J. 
Published: January 2012

AbstractPublished in the seriesAnalyses of Hazardous Substances in Biological Materials, Vol. 1 (1985)The article contains sections titled:General principlesEquipment, chemicals and solutionsEquipmentChemicalsSolutionsCalibration standardsSpecimen collection and sample treatmentOperational parameters for gas chromatographyAnalytical determinationHemoglobin determinationCalibrationCalculation of the analytical resultStandardization and quality controlReliability of the methodPrecisionAccuracyDetection limitSources of errorDiscussion of the method
β2‐Mikroglobulin [Biomonitoring Methods in German language, 1991]
Authors: Schaller K. H. , Lewalter J. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 10. Lieferung, Ausgabe 1991
Chlorophenoxycarboxylic acids (4‐Chloro‐2‐methylphenoxy‐ acetic acid; 2,4‐Dichlorophenoxyacetic acid; 4‐Chloro‐2‐methylphenoxy‐propionic acid; 2,4‐Dichlorophenoxypropionic acid) [Biomonitoring Methods, 1996]
Authors: Krämer W. , Merz W. , Ziemer W. 
Published: January 2012

Abstract

Published in the series
Analyses of Hazardous Substances in Biological Materials
, Vol. 5 (1996)

The article contains sections titled:

General principles

Equipment, chemicals and solutions

Equipment

Chemicals

Solutions

Calibration standards

Preparation of the C 18 cartridge

Specimen collection and sample preparation

Operational parameters for gas chromatography

Analytical determination

Calibration

Calculation of the analytical result

Standardization and quality control

Reliability of the method

Precision

Accuracy

Detection limit

Sources of error

Discussion of the method
Chlorobenzenes (1,2‐ and 1,4‐Dichlorobenzene, 1,2,4‐Trichlorobenzene) [Biomonitoring Methods, 1985]
Authors: Eben A. 
Published: January 2012

Abstract

Published in the series
Analyses of Hazardous Substances in Biological Materials
, Vol. 1 (1985)

The article contains sections titled:

General principles

Equipment, chemicals and solutions

Equipment

Chemicals

Calibration standards

Specimen collection and sample treatment

Operational parameters for gas chromatography

Packed column

Capillary column

Analytical determination

Calibration

Calculation of the analytical result

Reliability of the method

Precision

Accuracy

Detection limit

Sources of error

Discussion of the method
Chlorinated aromatic hydrocarbons (o‐, m‐, p‐dichlorobenzene; 1,2,4‐ trichlorobenzene; 1,2,4,5‐tetra‐ chlorobenzene; pentachlorobenzene; hexachlorobenzene) [Biomonitoring Methods, 1991]
Authors: Lewalter J. , Ellrich D. 
Published: January 2012

Abstract

Published in the series
Analyses of Hazardous Substances in Biological Materials
, Vol. 3 (1991)

The article contains sections titled:

General principles

Equipment, chemicals and solutions

Equipment

Chemicals

Calibration standards

Specimen collection and sample preparation

Operational parameters for gas chromatography

Analytical determination

Calibration

Calculation of the analytical result

Standardization and quality control

Reliability of the method

Precision

Accuracy

Detection limit

Sources of error

Discussion of the method
Isopropylbenzol (Cumol) [Biomonitoring Methods in German language, 1983]
Authors: Goenechea S. 
Published: January 2012

Abstract

Veröffentlicht in der Reihe
Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material
, 7. Lieferung, Ausgabe 1983

Der Artikel enthält folgende Kapitel:

Grundlage des Verfahrens
Nitroaromatic compounds (nitrobenzene, p‐nitrotoluene, p‐nitrochlorobenzene, 2,6‐dinitrotoluene, o‐dinitrobenzene, 1‐nitronaphthalene, 2‐nitronaphthalene, 4‐nitrobyphenyl) [Biomonitoring Methods, 1991]
Authors: Lewalter J. , Ellrich D. 
Published: January 2012

AbstractPublished in the seriesAnalyses of Hazardous Substances in Biological Materials, Vol. 3 (1991)The article contains sections titled:General principlesEquipment, chemicals and solutionsEquipmentChemicalsCalibration standardsSpecimen collection and sample preparationOperational parameters for gas chromatographyAnalytical determinationCalibrationCalculation of the analytical resultStandardization and quality controlReliability of the methodPrecisionAccuracyDetection limitSources of errorDiscussion of the method
Aromatic Amines (1‐Naphthylamine; 2‐Naphthylamine; 4,4′‐Methylene‐bis(2‐chloroaniline); 3,3′‐Dichlorobenzidine) [Biomonitoring Methods, 1985]
Authors: Angerer J. , Lewalter J. , Neumann H.‐G. , Schaller K. H. 
Published: January 2012

Abstract

Published in the series
Analyses of Hazardous Substances in Biological Materials
, Vol. 1 (1985)

The article contains sections titled:

General principles

Equipment, chemicals and solutions

Equipment

Chemicals

Solutions

Calibration standards

Specimen collection and sample treatment

Operational parameters for high‐pressure liquid chromatography

Analytical determination

Calibration

Calculation of the analytical result

Reliability of the method

Precision

Accuracy

Detection limit

Sources of error

Discussion of the method
Acetylcholinesterase [Biomonitoring Methods in German language, 1982]
Authors: Pilz W. 
Published: January 2012

Abstract

Veröffentlicht in der Reihe
Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material
, 6. Lieferung, Ausgabe 1982

Der Artikel enthält folgende Kapitel:

Zusammenfassung

Geräte, Chemikalien und Lösungen

Geräte

Chemikalien

Lösungen

Probenahme und Probenaufbereitung

Analytische Bestimmung

Berechnung des Analysenergebnisses

Beurteilung des Verfahrens

Störeinflüsse

Diskussion der Methode
Gaschromatographische Methoden zur Bestimmung organischer Substanzen in biologischem Material [Biomonitoring Methods in German language, 1991]
Authors: Angerer J. , König W. A. , Machata G. , Muffler H. , Schaller K. H. , Schulte E. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 10. Lieferung, Ausgabe 1991Der Artikel enthält folgende Kapitel:Gaschromatographische Methoden zur Bestimmung organischer Substanzen in biologischem MaterialEinleitungProbengewinnung und ‐aufbereitungProbenaufgabe und EinlaßsystemeSäulenDetektorenAuswertungQualitätssicherung
Haemoglobin adducts of aromatic amines: aniline, o‐, m‐ and p‐toluidine, o‐anisidine, p‐chloroaniline, α‐and β‐naphthylamine, 4‐aminodiphenyl, benzidine, 4,4′‐diaminodiphenylmethane, 3,3′‐dichlorobenzidine [Biomonitoring Methods, 2000]
Authors: Lewalter J. , Gries Examiners: J. Angerer W. , Sabbioni G. 
Published: January 2012

Abstract

Published in the series
Analyses of Hazardous Substances in Biological Materials
, Vol. 7 (2000)

The article contains sections titled:

General principles

Equipment, chemicals and solutions

Equipment

Chemicals

Solutions and conditioning of the extraction material

Calibration standards

Specimen collection, storage, sample preparation and sample processing

Specimen collection

Storage

Sample preparation

Sample processing

Operational parameters

Operational parameters for gas chromatography

MS operational conditions

Analytical determination

Calibration

Calculation of the analytical result

Standardisation and quality control

Reliability of the method

Precision

Accuracy

Detection limits

Sources of error

Discussion of the method
δ‐Aminolävulinsäure [Biomonitoring Methods in German language, 1978a]
Authors: Angerer J. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 2. Lieferung, Ausgabe 1978Der Artikel enthält folgende Kapitel:ZusammenfassungGeräte, Chemikalien und LösungenGeräteChemikalienLösungenVergleichsstandardProbenahme und ProbenaufbereitungEichungAnalytische BestimmungBerechnung der AnalysenergebnisseQualitätssicherungBeurteilung des VerfahrensPräzisionRichtigkeitNachweisgrenzeStöreinflüsseDiskussionδ‐Aminolävulinsäure (ALA)
Koproporphyrin [Biomonitoring Methods in German language, 1978b]
Authors: Schaller K.H. 
Published: January 2012

Abstract

Veröffentlicht in der Reihe
Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material
, 2. Lieferung, Ausgabe 1978

Der Artikel enthält folgende Kapitel:

Zusammenfassung

Geräte, Chemikalien und Lösungen

Geräte

Chemikalien

Lösungen

Probenahme und Probenaufbereitung

Eichung

Analytische Bestimmung

Berechnung des Analysenergebnisses

Beurteilung des Verfahrens

Präzision

Richtigkeit

Nachweisgrenze

Störeinflüsse

Diskussion

Koproporphyrin
Erythrozytenporphyrine (freie) [Biomonitoring Methods in German language, 1988]
Authors: Lewalter J. , Schaller K. H. , Domik C. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 9. Lieferung, Ausgabe 1988Der Artikel enthält folgende Kapitel:Grundlage des VerfahrensGeräte, Chemikalien und LösungenGeräteChemikalienLösungenVergleichsstandardsProbenahme und ProbenaufbereitungProbenahmeIsolierung der ErythrozytenProbenaufbereitungAnalytische BestimmungBestimmung des HämatokritsKalibrierungBerechnung des AnalysenergebnissesBeurteilung des VerfahrensPräzisionRichtigkeitNachweisgrenzeStöreinflüsseDiskussion der Methode
Hochleistungflüssigchromatographische Verfahren zur Bestimmung organischer Substanzen in biologischem Material [Biomonitoring Methods in German language, 2000]
Authors: Boos K.‐S. , Blaszkewicz M. , Gündel J. , Heinrich‐Ramm R. , Lintelmann J. , Müller G. , Schaller K.‐H. , Will W. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 14. Lieferung, Ausgabe 2000Der Artikel enthält folgende Kapitel:Hochleistungsflüssigchromatographische Verfahren zur Bestimmung organischer Substanzen in biologischem MaterialEinleitungPräanalytische PhaseProbenaufbereitungGrundoperationenDer flüssigchromatographische ProzessKomponenten eines HPLC‐SystemsMesswerterfassung und QuantifizierungQualitätssicherung
Die Verwendung der Flüssigkeitschromatographie / Massenspektrometrie (LC/MS) im biologischen Monitoring [Biomonitoring Methods in German language, 2008]
Authors: Müller M. , Völkel W. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 18. Lieferung, Ausgabe 2008Der Artikel enthält folgende Kapitel:Die Verwendung der Flüssigkeitschromatographie /Massenspektrometrie (LC/MS) im biologischen MonitoringEinleitungAufbau der Flüssigkeitschromatographie/ Massenspektrometrie‐KopplungAspekte der Methodenentwicklung und ‐optimierungAusblick
Suszeptibilitätsmarker [Biomonitoring Methods in German language, 2004]
Authors: Thier R. , Pesch B. , Krause G. , Schulz T. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 16. Lieferung, Ausgabe 2004Der Artikel enthält folgende Kapitel:Suszeptibilitätsmarker
Grundlagen der Polymerasekettenreaktion (PCR) [Biomonitoring Methods in German language, 2004]
Authors: Krause G. , Scherer G. , Müller M. , Weiß T. 
Published: January 2012

AbstractVeröffentlicht in der ReiheAnalytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe: Analysen in biologischem Material, 16. Lieferung, Ausgabe 2004Der Artikel enthält folgende Kapitel:Grundlagen der Polymerasekettenreaktion (PCR)Das Prinzip der PCREntwicklung der PCR‐TechnikEinsatzmöglichkeiten der PolymerasekettenreaktionAblauf eines typischen PCR‐Experiments zur GenotypisierungPCR‐MethodikAuswertung von PCR‐ExperimentenFehlermöglichkeiten und notwendige Kontrollen (Yap et al.)Methodische Grundlagen der LightCycler‐gestützten Realtime‐PCRQualitätssicherung
Reliability criteria for analytical methods [Biomonitoring Methods, 2010]
Authors: Bader M. , Barr D. , Göen T. , Schaller K.H. , Scherer G. , Angerer J. 
Published: January 2012

Abstract

Published in the series
Biomonitoring Methods
, Vol. 12 (2010)

The article contains sections titled:

Introduction

Pre‐analytical phase

Prevention of external contamination during sample collection

Sampling time

Sampling material

Storage and transport of samples

Sample documentation

Stability of the chemicals, solutions and calibration standards used

Selectivity

Detection, identification and quantification limits

Visual estimation

Determination of the signal/background noise ratio

Blank value procedure according to DIN 32 645

Calibration curve procedure according to DIN 32 645

Standard deviation procedure

Example

Calibration

Selection of the calibration points

One‐point calibration

Matrix effects

Use of internal standards

Linearity of the calibration function

Example

Precision

Example

Accuracy

Reference material (CRM)

Reference methods

Inter‐laboratory comparability investigations

Spiking procedures

Arithmetical determination of accuracy

Factors influencing accuracy

Comparability of methods

Examples

Measurement uncertainty

Combined and extended measurement uncertainty

Estimation of the measurement uncertainty

Examples

Quality assurance

Internal quality assurance

External quality assurance

Summary

Glossary
Risk factors for Raynaud's phenomenon in the workforce
Authors: Roquelaure Yves , Ha Catherine , Le Manac'h Audrey Petit , Bodin Julie , Bodere Anaïs , Bosseau Christian , Descatha Alexis , Leclerc Annette , Goldberg Marcel , Imbernon Ellen 
Published: January 2012

AbstractObjectiveTo assess the prevalence of and risk factors for Raynaud's phenomenon (RP) in a French working population characterized by various levels of exposure to work‐related constraints.MethodsThe study population comprised 3,710 workers (2,161 men and 1,549 women) who were followed up by 83 occupational physicians and were representative of the region's workforce. RP, as diagnosed by a questionnaire and a standardized interview, was defined as the occurrence of at least occasional attacks of finger blanching triggered by exposure to environmental cold during the previous 12 months. Personal factors and work exposure were assessed by self‐administered questionnaires. The associations between RP and personal and occupational factors were analyzed using logistic regression modeling.ResultsA total of 87 cases of RP (56 women and 31 men) were diagnosed. The population‐based annual prevalence rates of RP were 3.6% (95% confidence interval [95% CI] 2.7–4.5%) for women and 1.4% (95% CI 0.9–1.9%) for men. Women had a higher risk of RP (odds ratio [OR] 2.1 [95% CI 1.3–3.4]) and the risk decreased continuously with body mass index (OR for 1‐kg/m2 increment 0.87 [95% CI 0.81–0.94]). The risk of RP increased consistently but moderately with age after 35 years (ORs ranging from 2.0 [95% CI 1.1–3.8] to 2.9 [95% CI 1.6–5.2]). Among the work‐related factors studied, RP was associated with an exposure to a cold environment or objects (OR 2.2 [95% CI 1.0–4.6]), a high repetitiveness of a task (OR 1.7 [95% CI 1.0–2.7]), a high psychological demand at work (OR 1.7 [95% CI 1.0–2.7]), and low support from supervisors (OR 2.4 [95% CI 1.5–3.8]).ConclusionPersonal and work‐related factors were associated with RP, with a clear difference between the sexes. Work‐related psychosocial stressors played a significant role independently of biomechanical and environmental exposure.
Novel CLDN14 mutations in Pakistani families with autosomal recessive non‐syndromic hearing loss
Authors: Lee Kwanghyuk , Ansar Muhammad , Andrade Paula B. , Khan Bushra , Santos‐Cortez Regie Lyn P. , Ahmad Wasim , Leal Suzanne M. 
Published: January 2012

AbstractMutations in the CLDN14 gene are known to cause autosomal recessive (AR) non‐sydromic hearing loss (NSHL) at the DFNB29 locus on chromosome 21q22.13. As part of an ongoing study to localize and identify NSHL genes, the ARNSHL segregating in four Pakistani consanguineous families were mapped to the 21q22.13 region with either established or suggestive linkage. Given the known involvement of CLDN14 gene in NSHL, DNA samples from hearing‐impaired members from the four families were sequenced to potentially identify causal variants within this gene. Three novel CLDN14 mutations, c.167G>A (p.Trp56*), c.242G>A (p.Arg81His), and c.694G>A (p.Gly232Arg), segregate with hearing loss (HL) in three of the families. The previously reported CLDN14 mutation c.254T>A (p.Val85Asp) was observed in the fourth family. None of the mutations were detected in 400 Pakistani control chromosomes and all were deemed damaging based on bioinformatics analyses. The non‐sense mutation c.167G>A (p.Trp56*) is the first stop codon mutation in CLDN14 gene to be identified to cause NSHL. The c.242G>A (p.Arg81His) and c.694G>A (p.Gly232Arg) mutations were identified within the first extracellular loop and the carboxyl‐tail of claudin‐14, respectively, which highlights the importance of the extracellular domains and phosphorylation of cytoplasmic tail residues to claudin function within the inner ear. The HL due to novel CLDN14 mutations is prelingual, severe‐to‐profound with greater loss in the high frequencies. © 2012 Wiley Periodicals, Inc.
Segmental maternal uniparental disomy 7q associated with DLK1/GTL2 (14q32) hypomethylation
Authors: Begemann Matthias , Spengler Sabrina , Kordaß Ulrike , Schröder Carmen , Eggermann Thomas 
Published: January 2012

AbstractAberrant methylation at different imprinted loci has been reported for several congenital imprinting disorders, that is, Silver–Russell syndrome (SRS), but the coincidental occurrence of aberrant methylation and uniparental disomy (UPD) has not yet been described. We report on a patient initially diagnosed with SRS carrying a segmental maternal UPD of chromosome 7 [upd(7q)mat]. By further screening the patient's DNA for methylation defects on other chromosomes we identified a hypomethylation of the paternally methylated DLK1/GTL2 locus in 14q32, an epigenotype typically associated with the upd(14)mat phenotype. Detailed clinical analysis confirmed the molecular finding in the patient indicating that the 14q32 epimutation was clinically preponderant. The parallel occurrence of upd(7q)mat and a DLK1/GTL2 hypomethylation in the same patient is a unique finding. Indeed, both disturbances might have occurred coincidentally, but it can also be hypothesized that the upd(7q)mat as the initial genomic mutation represents a trans‐acting mutation causing an aberrant methylation in 14q32. © 2012 Wiley Periodicals, Inc.
Mucopolysaccharidosis type II in females and response to enzyme replacement therapy
Authors: Jurecka Agnieszka , Krumina Zita , Żuber Zbigniew , Różdżyńska‐Świątkowska Agnieszka , Kłoska Anna , Czartoryska Barbara , Tylki‐Szymańska Anna 
Published: January 2012

AbstractMucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X‐linked lysosomal storage disease caused by a deficiency of iduronate‐2‐sulfatase (IDS). Two affected girls with moderate and severe forms of MPS II with normal karyotypes and increased urinary dermatan sulphate and heparin sulphate excretion and marked deficiencies of IDS activity are reported. Molecular studies showed that case 1 has a heterozygous mutation c.1568A > G (p.Y523C) associated with almost totally skewed inactivation of the normal maternal X chromosome, and case 2 has a heterozygous deletion that includes exons 1–4 of IDS (minimal deletion range c.1–103_184del). The multi‐exon deletion correlated with early onset of the disease and severe phenotype with intellectual disability, whereas the missense mutation was associated with moderate developmental delay. Although genotype–phenotype correlation in MPS II is difficult, gene deletions seem to correlate with more severe clinical manifestation of the disease. Enzyme replacement therapy (ERT) in these two females resulted in disease stabilization in both. © 2012 Wiley Periodicals, Inc.
Anthropometric charts for infants with trisomies 21, 18, or 13 born between 22 weeks gestation and term: The VON charts
Authors: Boghossian Nansi S. , Horbar Jeffrey D. , Murray Jeffrey C. , Carpenter Joseph H. ,   for the Vermont Oxford Network
Published: January 2012

AbstractData on birth weight for gestational age (GA) are not well described for infants with trisomy 21 (T21), trisomy 18 (T18), or trisomy 13 (T13). We report on anthropometric charts of infants with these conditions using data from the Vermont Oxford Network (VON). Data from a total of 5,147 infants with T21 aged 22–41 weeks, 1,053 infants with T18 aged 22–41 weeks, and 613 infants with T13 aged 22–40 weeks were used to create birth weight for GA charts. Head circumference for GA charts were created for infants with T21 only. Combined‐sex charts were generated for infants with T18 or T13 while sex‐specific charts were generated for infants with T21. Smoothed centiles were created using LmsChartMaker Pro 2.3. Among the three examined groups, infants with T18 were the most likely to be growth restricted while infants with T21 were the least likely to be growth restricted. The new charts for infants with T21 were also compared to the Lubchenco and Fenton charts and both show frequent misclassification of infants with T21 as small or large for GA. The new charts should prove to be useful, especially for infants with T21, to assist in medical management and guide nutrition care decisions. © 2012 Wiley Periodicals, Inc.