bluuebunny/crossref_metadata_2025_split huggingface dataset:
Removal of thiophene compounds from model fuel with supported copper on active carbon, adsorption kinetics, and isotherms
Authors: Kazemi Bahador , Golipour Haleh , Mafi Morteza , Mokhtarani Babak 
Published: June 2024

AbstractIn this study, the adsorption of thiophene compounds (TCs), including thiophene (T), benzothiophene (BT), and dibenzothiophene (DBT), from model fuels was investigated using modified activated carbon (AC). The model fuel, prepared as a single‐solute model at a concentration of 2000 ppm based on a mixture concentration of 3000 ppm, served as the basis for the adsorption experiments. Additionally, an examination of thiophene adsorption from commercial fuels, specifically kerosene, was conducted. Experimental data were used to calculate correlated parameters of adsorption isotherms, kinetic models, and the Fisher factor. The pseudo‐second‐order model demonstrated the best fit to the experimental data. Notably, the adsorbent consisting of 10% Cu+ supported on acid‐washed activated carbon (A1CN10) exhibited the highest adsorption capacity for TCs, achieving removal percentages of 78%, 96%, and 100% for T, BT, and DBT, respectively. Various methods were employed to investigate the physicochemical properties of the adsorbents, including N2 adsorption–desorption surface analysis (BET), scanning electron microscopy (SEM), X‐ray diffraction (XRD), and energy dispersive spectroscopy (EDS). Furthermore, the regeneration of the adsorbent was studied using two techniques: agitation and ultrasound.
Polyoxometalates Based Catalysts for Carbonylation Reactions: A Review
Authors: Zhang Xuehua , Tang Dechang , He Lin , Cao Yanwei 
Published: June 2024

AbstractAs a type of diverse and structurally adjustable metal‐oxo clusters, polyoxometalates (POMs) based materials have been extensively applied as a catalysis in various valuable reactions. This review summarized recent progress in the application of POMs‐based catalysts for various carbonylation reactions including (1). Carbonylation of olefins, (2). Carbonylation of formaldehyde, (3). Carbonylation of methanol or dimethyl ether, (4). Oxidative carbonylation of methane, (5). Oxidative carbonylation of phenol and (6). Reductive carbonylation of nitrobenzene. A brief perspective on POMs‐based catalysts for the carbonylation reactions is proposed.
Recurrence patterns following nephrectomy for renal cell carcinoma in a Danish nationwide cohort
Authors: Bencina Goran , Billeskov Rolf , Bak Rasmine , Al‐Sabbagh Ahmed , Pedersen Julie Højgaard , Lunetcas Marina , Heeno Emma , Tolouee Sara , Ashraf Tuba , Fristrup Niels , Azawi Nessn 
Published: June 2024

AbstractObjectivesThis study aimed to characterize the demographic and clinical features of patients with renal cell carcinoma (RCC) post‐surgery for localized or locally advanced disease in a national Danish cohort, with a specific focus on describing recurrence patterns in a subgroup aligned with the adjuvant KEYNOTE‐564 trial classification.MethodsThis was a retrospective analysis of the Danish Renal Cancer (DaRenCa) database. Eligible subjects were individuals with an RCC diagnosis between January 2014 and December 2017 who subsequently underwent radical or partial nephrectomy. Variables of interest were demographic and clinical characteristics, rates and sites of recurrence. Recurrence rates were also assessed in a subpopulation stratified using the risk classifications of the KEYNOTE‐564 trial.ResultsA total of 2164 RCC patients were identified. Most patients (84.8%) had non‐metastatic RCC (stage M0). A recurrence was observed in 250 of the M0 patients (13.6%). Patients with a recurrence were older, male, had a higher tumour stage, had undergone radical nephrectomy and had a higher Leibovich score. The majority (74.8%) of M0 patients had recurrence at distant metastatic sites. A total of 392 patients were stratified by the KEYNOTE‐564 risk classification: 335 intermediate‐high risk, 17 high risk and 40 M1 NED (metastatic with no evidence of disease). Recurrence was observed in 37.0%, 88.2% and 27.5% of these risk groups, respectively.ConclusionsThis study elucidates the rates and determinants of post‐surgical RCC recurrence in Denmark, underscoring the potential of adjuvant immunotherapy in refining therapeutic strategies, identifying suitable beneficiaries and minimizing overtreatment risks in RCC care.
Preference for social stimuli: A comparison of stimulus modes used in preference assessments
Authors: Wilson Shannon , Cividini‐Motta Catia , MacNaul Hannah , Salinas Rebecca , Ferrer Geninna 
Published: June 2024

AbstractSocial stimuli are some of the most commonly used reinforcers. Previous research shows that preference for social stimuli can be identified using paired‐stimulus preference assessments (PSPA) employing various stimulus modes (e.g., pictures of the actual social stimuli). To date, no study has evaluated the correspondence in preference for social stimuli identified via PSPAs completed using three differing stimulus modes. Therefore, this study compared the correspondence in preference hierarchy identified via PSPAs completed using video of the social stimuli (VSM), pictures of the actual social stimuli (PSM‐A), and drawings of the social stimuli (PSM‐D) and whether preference hierarchy remained stable over repeated administration of the PSPAs (i.e., 1 month). Moreover, we assessed participants' preference for the three types of stimulus modes. Results demonstrated that during the initial PSPAs, preference hierarchies were most similar across the PSPAs completed using VSM and PSM‐A, that preference was most stable across repeated administration of the PSPAs completed using the VSM, and that participants' preference for differing stimulus modes was idiosyncratic. Moreover, the PSPAs completed using the VSM required the longest amount of time to create materials and administer the assessment.
The influence of board characteristics, ownership structure and public attention on climate change disclosure in banking sector companies
Authors: Octavio Muhammad Fadhly Rizky , Setiawan Doddy 
Published: June 2024

AbstractThis study aims to analyze the influence of board characteristics, ownership structure, and public attention on the disclosure of information related to climate change in the banking industry. This study uses panel data from financial reports and corporate sustainability in the banking sector. The data is processed using the Eviews application, using a sample of 348 companies from 2018 to 2021. The results show that the presence of women on the board, foreign board members, foreign ownership, and public attention all have a positive and significant effect influence. In contrast, board size and institutional ownership have a negative influence on the disclosure of climate change information by banking companies in different countries. Statistical tests also show that although the level of climate change information disclosure by banking companies is relatively good, there is still room for improvement to be in line with evolving standards. The study also looks at public attention through media coverage, as measured through Google Trends, which has the potential to impact climate change information disclosure, especially in sectors that are sensitive to the issue. Furthermore, the study conducted additional tests by categorizing the sample based on companies located in countries with high and medium rankings in the climate change performance index, as well as grouping them by region (Asia, Americas, and Europe). This research has important practical and theoretical contributions, advancing the understanding of the application of legitimacy and stakeholder theories to climate change and the factors that influence climate change disclosure strategies.
The regulatory roles and clinical significance of glycolysis in tumor
Authors: Qiao Qiqi , Hu Shunfeng , Wang Xin 
Published: June 2024

AbstractMetabolic reprogramming has been demonstrated to have a significant impact on the biological behaviors of tumor cells, among which glycolysis is an important form. Recent research has revealed that the heightened glycolysis levels, the abnormal expression of glycolytic enzymes, and the accumulation of glycolytic products could regulate the growth, proliferation, invasion, and metastasis of tumor cells and provide a favorable microenvironment for tumor development and progression. Based on the distinctive glycolytic characteristics of tumor cells, novel imaging tests have been developed to evaluate tumor proliferation and metastasis. In addition, glycolytic enzymes have been found to serve as promising biomarkers in tumor, which could provide assistance in the early diagnosis and prognostic assessment of tumor patients. Numerous glycolytic enzymes have been identified as potential therapeutic targets for tumor treatment, and various small molecule inhibitors targeting glycolytic enzymes have been developed to inhibit tumor development and some of them are already applied in the clinic. In this review, we systematically summarized recent advances of the regulatory roles of glycolysis in tumor progression and highlighted the potential clinical significance of glycolytic enzymes and products as novel biomarkers and therapeutic targets in tumor treatment.
Three New Polyphenol Derivatives from the Fruits of Macaranga Monandra and their Antioxidant Potential
Authors: Guizoko Toko Einstein , Emar Djappa Tchapo Carlain , Tontsa Tsamo Armelle , Kemzeu Raoul , Wang Yan , Boyom Fekam Fabrice , Tantoh Ndinteh Derek , Iqbal Choudhary Muhammad , Nkengfack Ephrem Augustin , Mpho Mmutlane Edwin , Mkounga Pierre 
Published: June 2024

AbstractPhytochemical investigation of the methanol extract from the fruits of Macaranga monandra (Euphorbiaceae Muell. et Arg.) afforded one new geranylated 1’,2’‐dihydrophenanthrene and two new flavonoid derivatives, named macamondrin (1), macamondrione A (2) and B (3) respectively. The structures of these compounds were elucidated mainly by NMR, mass spectral data and in comparison with data from the literature. Along with compounds 1–3, nine known compounds among which oleanolic acid (4); daucosterol (5); 3β‐acetoxy‐11α,12α‐epoxytaraxerol (6); 3,3’,4‐tri‐O‐methylellagic acid (7); 3,3’,4,4’‐tetra‐O‐methylellagic acid (8); 4’‐O‐methyl‐6‐isoprenylapigenin (9); 4’‐O‐methyl‐8 isoprenylkaempférol (10); 4’‐O‐methyl‐6‐isoprénylkaempférol (11); 6‐isoprénylkaempférol (12), were also isolated. Crude extracts as well as isolated compounds were evaluated for their antioxidant activity using the ABTS, DPPH and FRAP methods. It appears that the 50 % radical scavenging concentrations ranging from 6.26 to 11.7 μg/ml on the ABTS radical, from 1.77 to 48.22 μg/ml on the DPPH radical, and from 1.54 to 67.97 μg/ml with the FRAP method. For the compounds tested, very good antioxidant activities were observed, which clearly shows that these molecules can have an anti oxidative stress potentiel.
Copper/Tin Nanocomposites‐Loaded Exosomes Induce Apoptosis and Cell Cycle Arrest at G0/G1 Phase in Skin Cancer Cell Line
Authors: Abd‐Rabou Ahmed A. , Kishta Mohamed S. , Yakout Saad M. , Youssef Ahmed M. , Abdallah Ahmed N. , Ahmed Hanaa H. 
Published: June 2024

AbstractThis study aims to explore the efficacy of Copper/Tin (CuS/SnS) nanocomposites loaded into exosomes against skin cancer A431 cell line. CuS/SnS nanocomposites (S1, S2, S3) were synthesized and characterized, then loaded into exosomes (Exo) (S1‐Exo, S2‐Exo and S3‐Exo) and characterized. After that, the loaded samples were investigated in vitro against A431 using cytotoxicity, apoptosis, and cell cycle assays. CuS/SnS nanocomposites were indexed to hexagonal CuS structure and orthorhombic α‐SnS phase and showed nano‐rode shape. The exosomes loaded with nanocomposites were regular and rounded within the size of 120 nm, with no signs of broken exosomes or leakage of their contents. The cytotoxicity assay indicated the enhanced cytotoxic of S1‐Exo versus the free nano‐form S1 on A431. Interestingly, S1‐Exo recorded 1.109 times more than DOX in its anti‐skin cancer capacity. Moreover, S1‐Exo recorded 40.2 % for early apoptosis and 22.1 % for late apoptosis. Furthermore, it displayed impact in arresting the cancer cell cycle at G0/G1 phase and reducing G2/M phase. Noteworthy, loaded nanocomposites were safe against normal HSF skin cells. In conclusion, the loaded CuS/SnS nanocomposites into the exosomes could be of great potential as anti‐skin cancer candidates through induction of apoptosis and promotion of the cell cycle arrest at G0/G1 phase.
Dust Explosibility and Severity of Bayan and Tanito Coal
Authors: Wan Sulaiman Wan Zaiton , Mohd Idris Mohd Fadzil , Md Kasmani Rafiziana , Gimbun Jolius 
Published: June 2024

AbstractThe assessment of the explosibility and severity characteristics of Bayan coal and Tanito coal was investigated over various concentrations in a 20 L Siwek spherical explosion chamber. The coals tested in this study were also compared with other organic dusts such as palm‐based soap noodle, tea powder, black rice, and rice flour, which were tested using the same explosion chamber and procedures. The severity and explosibility of the coals increase as their concentration increases. The Pmax of Bayan coal (10.15 bar) is higher than that of Tanito coal (7.35 bar). The Kst of Bayan coal (48.04 bar m s−1) is also higher than that of Tanito coal (16.83 bar m s−1). Among all the dusts studied using the same chamber and procedures, palm‐based soap noodle has the highest Pmax at 16 bar, while tea powder has the lowest Pmax at 6.35 bar. The results show that the explosibility and severity of the coals increase as the concentrations increase, and the moisture content, coal ranking, and different types of organic dust have a significant influence on the severity characteristics of dust explosions.
Developing CAMELOT for assessing methodological limitations of qualitative research for inclusion in qualitative evidence syntheses
Authors: Munthe‐Kaas Heather M. , Booth Andrew , Sommer Isolde , Cooper Sara , Garside Ruth , Hannes Karin , Noyes Jane ,   The CAMELOT Development Group
Published: June 2024

AbstractIntroductionQualitative evidence is increasingly incorporated into decision‐making processes. Assessing the methodological limitations of primary studies is critical to making an overall assessment of confidence in findings from qualitative evidence syntheses (QES) using GRADE‐CERQual. Current critical appraisal tools were not developed specifically for use in Cochrane reviews or GRADE‐CERQual, and few are evidence‐based. The aim of CochrAne qualitative Methodological LimitatiOns Tool (CAMELOT) was to address this gap.MethodsWe undertook this project in four stages: (1) systematic literature search to identify existing tools, (2) identification of evidence to support inclusion of potential CAMELOT domains (3) consensus survey to agree on the inclusion and definition of CAMELOT domains, and (4) human‐centered design approach to develop and refine CAMELOT by exploring user experience.ResultsCAMELOT is a new evidence‐based tool for assessing the methodological strengths and limitations of primary qualitative research studies in a QES. CAMELOT is comprised of 12 domains: four Meta domains that encourage review authors to consider those characteristics of the primary study that are beyond how the study was carried out, but which inform the conduct and design of the study, and eight Method domains which encourage review authors to consider how the study was designed, planned and/or conducted, and how study conduct and design fits with the information provided in the four meta domains. Review authors make an assessment by identifying any concerns regarding the methods used in the study and considering the appropriateness of fit between the Meta and Method domains.ConclusionCAMELOT provides review authors with a transparent and systematic method to assess methodological limitations of primary qualitative studies. CAMELOT incorporates qualitative principles and focuses on appropriateness of fit between Meta and Method domains. In line with iterative tool development approach, CAMELOT will continue to be revised over time following extensive user testing and piloting.
The searchbuildR shiny app: A new implementation of the objective approach for search strategy development in systematic reviews
Authors: Kapp Claudia , Fujita‐Rohwerder Naomi , Lilienthal Jona , Sieben Wiebke , Waffenschmidt Siw , Hausner Elke 
Published: June 2024

AbstractIntroductionOne of the main tasks in information retrieval is the development of Boolean search strategies for systematic searches in bibliographic databases. This includes the identification of free‐text terms and controlled vocabulary. IQWiG has previously implemented its objective approach for search strategy development using a fee‐based text analysis software. However, this implementation is not fully automated, due to a lack of technical options. The aim of our project was to develop a text analysis tool for the development of Boolean search strategies using R.MethodsWe adopt an incremental approach to software development, with the first goal being to develop a minimum viable product for the previously defined use cases. To create an interactive user interface, we use the shiny framework.ResultsOur newly developed shiny app searchbuildR is a text analysis tool with a point‐and‐click user interface, that automatically extracts and ranks terms from titles, abstracts, and MeSH terms of a given test set of PubMed records. It returns searchable, interactive tables of free‐text and MeSH terms. Each free‐text term can also be viewed within its original context in the full titles and abstracts or in a user‐defined word window. In addition, 2‐word combinations are extracted and also provided as an interactive table to help the user identify free‐text term combinations, that can be searched with proximity operators in Boolean searches. The results can be exported to a CSV file. The new implementation with searchbuildR was evaluated by validating the text analysis results against the results of the previously used fee‐based software.ConclusionsQWiG has developed the shiny app searchbuildR to support the development of search strategies in systematic reviews. It is open source and can be used by researchers and other information specialists without extensive R or programming skills. The package code is openly available on GitHub at www.github.com/IQWiG/searchbuildR.
Carbon fiber confined mixed Ni‐based crystal phases with interfacial charge redistribution induced by high bond polarity for electrochemical urea‐assisted hydrogen generation
Authors: Yin Chun , Li Jiaxin , Wang Shuli , Wen Huan , Yang Fulin , Feng Ligang 
Published: June 2024

AbstractInterfacial electronic structure modulation of nickel‐based electrocatalysts is significant in boosting energy‐conversion‐relevant urea oxidation reaction (UOR). Herein, porous carbon nanofibers confined mixed Ni‐based crystal phases of Ni2P and NiF2 are developed via fluorination and phosphorization of Ni coated carbon nanofiber (Ni2P/NiF2/PCNF), which possess sufficient mesoporous and optimized Gibbs adsorption free energy by mixed phase‐induced charge redistribution. This novel system further reduces the reaction energy barrier and improves the reaction activity by addressing the challenges of low intrinsic activity, difficulty in active site formation, and insufficient synergism. A considerably high current density of 254.29 mA cm−2 is reached at 1.54 V versus reversible hydrogen electrode on a glass carbon electrode, and the cell voltage requires 1.39 V to get 10 mA cm−2 in hydrogen generation, with very good stability, about 190 mV less than that of the traditional water electrolysis. The facile active phase formation and high charge transfer ability induced by asymmetric charge redistribution are found in the interface, where the urea molecules tend to bond with Ni atoms on the surface of heterojunction, and the rate‐determining step is changed from CO2 desorption to the fourth H‐atom deprotonation. The work reveals a novel catalyst system by interfacial charge redistribution induced by high bond polarity for energy‐relevant catalysis reactions.
Fully carbonate‐electrolyte‐based high‐energy‐density Li–S batteries with solid‐phase conversion
Authors: Hakari Takashi , Kameoka Yuto , Kishida Kaihei , Ozaki Shinji , Murata Chihiro , Deguchi Minako , Harada Ryo , Fujisawa Tomoki , Mizuno Yusuke , Nishikawa Heisuke , Tamura Tomoyuki , Wang Yiqun , Takahara Hikari , Aoki Takashi , Inamasu Tokuo , Okuda Daisuke , Ishikawa Masashi 
Published: June 2024

AbstractCarbonate‐electrolyte‐based lithium–sulfur (Li–S) batteries with solid‐phase conversion offer promising safety and scalability, but their reversible capacities are limited. In addition, large‐format pouch cells are paving the way for large‐scale production. This study demonstrates the in situ formation of a solid‐electrolyte interphase (SEI) as a protective layer using vinylene carbonate (VC), highlighting its industrial adaptability. A high reversible capacity is achieved by the lithiated poly‐VC SEI formed inside the cathode particles as a nanoscale ionic conduction path, along with the traditional surface protective layer. Furthermore, the severe dissolution of poly‐VC is mitigated by LiF derived from fluorine ethylene carbonate as a co‐solvent, enabling high rate performance and a long cycle life. A large 8 Ah pouch cell is successfully developed, which shows a high energy density of 400 Wh kg−1 based on the cell weight. This work demonstrates the high performance of large‐scale Li–S batteries with the in situ formation of a protective layer as a scalable technique for future applications.
Dynamic changes in mitochondrial localization in human neocortical basal radial glial cells during cell cycle
Authors: Gkini Vasiliki , Gómez‐Lozano Inés , Heikinheimo Oskari , Namba Takashi 
Published: June 2024

AbstractMitochondria play critical roles in neural stem/progenitor cell proliferation and fate decisions. The subcellular localization of mitochondria in neural stem/progenitor cells during mitosis potentially influences the distribution of mitochondria to the daughter cells and thus their fates. Therefore, understanding the spatial dynamics of mitochondria provides important knowledge about brain development. In this study, we analyzed the subcellular localization of mitochondria in the fetal human neocortex with a particular focus on the basal radial glial cells (bRGCs), a neural stem/progenitor cell subtype attributed to the evolutionary expansion of the human neocortex. During interphase, bRGCs exhibit a polarized localization of mitochondria that is localized at the base of the process or the proximal part of the process. Thereafter, mitochondria in bRGCs at metaphase show unpolarized distribution in which the mitochondria are randomly localized in the cytoplasm. During anaphase and telophase, mitochondria are still localized evenly, but mainly in the periphery of the cytoplasm. Mitochondria start to accumulate at the cleavage furrow during cytokinesis. These results suggest that the mitochondrial localization in bRGCs is tightly regulated during the cell cycle, which may ensure the proper distribution of mitochondria to the daughter cells and, thus in turn, influence their fates.