bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiple Synchronous Spinal Dural Arteriovenous Fistulas: A Systematic Literature Review
Authors: Ikeuchi Yusuke , Fujita Atsushi , Kohta Masaaki , Yamanishi Shunsuke , Tanaka Kazuhiro , Sasayama Takashi 
Published: April 2024

BACKGROUND AND OBJECTIVES:
Spinal dural arteriovenous fistulas (SDAVFs) lead to progressive neurological decline with symptoms such as paraparesis, bowel and bladder dysfunction, and sensory disturbances because of impaired spinal cord venous drainage. This study aimed to systematically review the literature on multiple synchronous SDAVFs and present 2 cases from our institution.

METHODS:
A comprehensive search was performed to identify all published cases of multiple synchronous SDAVFs. Overall, 23 patients with multiple synchronous SDAVFs were identified, including 21 from 19 articles and 2 from this study. The clinical presentation, lesion location, radiographic features, surgical treatment, and outcomes were analyzed in each patient.

RESULTS:
All patients in this study were male, and the duration from symptom onset to diagnosis in many of these patients was longer than that previously reported. Previous studies suggested that multiple SDAVFs typically occurred within 3 or fewer vertebral levels. However, >50% of the examined patients had remote lesions separated by more than 3 vertebral levels. Patients with remote lesions had a significantly worse outcome (1/7 vs 8/11, 95% CI 0.001-0.998; P = .049).

CONCLUSION:
Accurately locating fistulas before spinal angiography is critical for managing multiple remote SDAVFs. Considering the possibility of multiple remote SDAVFs, careful interpretation of imaging findings is essential for an accurate diagnosis and appropriate treatment planning.
Two sequential gene expression programs bridged by cell division support long-distance collective cell migration
Authors: Sun Jingjing , Durmaz Ayse Damla , Babu Aswini , Macabenta Frank , Stathopoulos Angelike 
Published: April 2024

ABSTRACT
The precise assembly of tissues and organs relies on spatiotemporal regulation of gene expression to coordinate the collective behavior of cells. In Drosophila embryos, the midgut musculature is formed through collective migration of caudal visceral mesoderm (CVM) cells, but how gene expression changes as cells migrate is not well understood. Here, we have focused on ten genes expressed in the CVM and the cis-regulatory sequences controlling their expression. Although some genes are continuously expressed, others are expressed only early or late during migration. Late expression relates to cell cycle progression, as driving string/Cdc25 causes earlier division of CVM cells and accelerates the transition to late gene expression. In particular, we found that the cell cycle effector transcription factor E2F1 is a required input for the late gene CG5080. Furthermore, whereas late genes are broadly expressed in all CVM cells, early gene transcripts are polarized to the anterior or posterior ends of the migrating collective. We show this polarization requires transcription factors Snail, Zfh1 and Dorsocross. Collectively, these results identify two sequential gene expression programs bridged by cell division that support long-distance directional migration of CVM cells.
Positive and negative durotaxis – mechanisms and emerging concepts
Authors: Mathieu Mathilde , Isomursu Aleksi , Ivaska Johanna 
Published: April 2024

ABSTRACT
Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, contractility and cell extrinsic cues. Integrins are the main adhesion receptors to ligands of the extracellular matrix (ECM), linking the actin cytoskeleton to the ECM and enabling cells to sense matrix rigidity and mount a directional cell migration response to stiffness gradients. Most models studied show preferred migration of single cells or cell clusters towards increasing rigidity. This is referred to as durotaxis, and since its initial discovery in 2000, technical advances and elegant computational models have provided molecular level details of stiffness sensing in cell migration. However, modeling has long predicted that, depending on cell intrinsic factors, such as the balance of cell adhesion molecules (clutches) and the motor proteins pulling on them, cells might also prefer adhesion to intermediate rigidity. Recently, experimental evidence has supported this notion and demonstrated the ability of cells to migrate towards lower rigidity, in a process called negative durotaxis. In this Review, we discuss the significant conceptual advances that have been made in our appreciation of cell plasticity and context dependency in stiffness-guided directional cell migration.
Pulsative venous return from the branchial vessels to the heart of the bivalve Mytilus galloprovincialis supports the constant-volume mechanism
Authors: Seo Eriko , Seo Yoshiteru 
Published: April 2024

ABSTRACT
In bivalves and gastropods, ventricle contraction causes a negative pressure in the auricles and increases venous return from the afferent oblique vein (AOV): the constant-volume (CV) mechanism. The flow in the AOV should be a pulsative flow synchronized with the ventricular contraction. The flow in the heart and adjacent vessels of Mytilus galloprovincialis were measured by magnetic resonance imaging to confirm this hypothesis. Under a regular heartbeat, pulsative flows in the AOV and branchial vessels (BVs) were almost completely synchronized with the flow in the aorta, while filling of the ventricle was in the opposite phase. Flows in the BVs were directed to the posterior direction, and a pair of BVs in the gill axes (the efferent BVs) were connected to the AOV. Based on the images of the whole pathway of the AOV in an oblique slice, we confirmed that haemolymph flow was evoked from the efferent BVs and flow into the ventricle via the auricle was completed in a single heartbeat. Therefore, the walls of the AOV and BVs could resist negative transmural pressure caused by the ventricular contraction. In conclusion, the auricle, the AOV and the BVs, including the gill filaments, act as a suction pump. The pulsative venous return is driven by the negative pressure of the AOV as in the CV mechanism, and the negative pressure in the efferent BVs could draw haemolymph from the sinus via the gill and the afferent BVs. Therefore, Mytilus can start and stop its heartbeat as necessary.
Effects of brief mindfulness training on smoking cue-reactivity in tobacco use disorder: Study protocol for a randomized controlled trial
Authors: Cheng Linlin , Luo Miaoling , Ge Jie , Fu Yu , Gan Quan , Chen Zhuangfei 
Published: April 2024

Background
The prevalence of Tobacco Use Disorder (TUD) represents a significant and pressing global public health concern, with far-reaching and deleterious consequences for individuals, communities, and healthcare systems. The craving caused by smoking cue is an important trigger for relapse, fundamentally hindering the cessation of cigarette smoking. Mindfulness interventions focusing on cue-reactivity was effective for the treatment of related dependence. Brief mindfulness training (BMT) meets the short-term needs for intervention but the effects still need to be examined. The objective of the present study is to investigate the impact of BMT intervention on smoking cue-reactivity among Chinese college students with TUD, to uncover the dynamic models of brain function involved in this process.

Method
A randomized control trial (RCT) based on electroencephalography (EEG) was designed. We aim to recruit 90 participants and randomly assign to the BMT and control group (CON) with 1:1 ratio. A brief mindfulness training will be administered to experimental group. After the intervention, data collection will be conducted in the follow-up stage with 5 timepoints of assessments. EEG data will be recorded during the smoking cue-reactivity task and ‘STOP’ brief mindfulness task. The primary outcomes include subjective reports of smoking craving, changes in EEG indicators, and mindfulness measures. The secondary outcomes will be daily smoking behaviours, affect and impulsivity, as well as indicators reflecting correlation between mindfulness and smoking cue-reactivity. To evaluate the impact of mindfulness training, a series of linear mixed-effects models will be employed. Specifically, within-group effects will be examined by analysing the longitudinal data. Additionally, the effect size for all statistical measurements will be reported, offering a comprehensive view of the observed effects.

Discussion
The current study aims to assess the impact of brief mindfulness-based intervention on smoking cue-reactivity in TUD. It also expected to enhance our understanding of the underlying processes involved in brain function and explore potential EEG biomarkers at multiple time points.

Trial registration
Trial registration number: ChiCTR2300069363, registered on 14 March 2023. Protocol Version 1.0., 10 April 2023.
Monocyte distribution width (MDW) kinetic for monitoring sepsis in intensive care unit
Authors: Agnello Luisa , Ciaccio Anna Maria , Del Ben Fabio , Lo Sasso Bruna , Biundo Giuseppe , Giglia Aurora , Giglio Rosaria Vincenza , Cortegiani Andrea , Gambino Caterina Maria , Ciaccio Marcello 
Published: April 2024

Abstract

Objectives
Monocyte distribution width (MDW) is a measure of monocyte anisocytosis. In this study, we assessed the role of MDW, in comparison to C-reactive protein (CRP), procalcitonin (PCT), and lactate, as a screening and prognostic biomarker of sepsis in intensive care unit (ICU) by longitudinally measuring it in the first 5 days of hospital stay.

Methods
We considered all consecutive patients admitted to the ICU. At admission, patients were classified as septic or not according to Sepsis-3 criteria. MDW, CRP, PCT, and lactate were measured daily in the first 5 days of hospitalization. ICU mortality was also recorded.

Results
We included 193 patients, 62 with sepsis and 131 without sepsis (controls). 58% and 26 % of the patients, with and without sepsis respectively, died during ICU stay. MDW showed the highest accuracy for sepsis detection, superior to CRP, PCT, and lactate (AUC of 0.840, 0.755, 0.708, 0.622, respectively). At admission, no biomarker predicts ICU mortality in patients with sepsis. The kinetic of all biomarkers during the first 5 days of hospitalization was associated with ICU mortality. Noteworthy, above all, the kinetic of MDW showed the best accuracy. Specifically, an increase or decrease in MDW from day 1–4 and 5 was significantly associated with mortality or survival, respectively.

Conclusions
MDW is a reliable diagnostic and prognostic sepsis biomarker, better than traditional biomarkers.
Galactagogue activity of poly-herbal decoction from Indonesia: a randomized open label controlled trial
Authors: Zulkarnain Zuraida , Fitriani Ulfa , Ardiyanto Danang , Saryanto  , Wijayanti Enggar , Triyono Agus , Novianto Fajar 
Published: April 2024

Abstract

Objectives
Indonesia have several herbs empirically used as galactagogue. However there are limited clinical evidence regarding the efficacy and safety of this herbs especially poly-herb. The aim of this study was to assess the efficacy and safety of polyherbal galactagogue (PHG) consist of katuk leaves, torbangun leaves and papaya leaves compared to commercial galactagogue capsules (CGC) that contain a single plant extract, katuk leaves.

Methods
This study was an open label randomized controlled trial with 120 subjects that randomly assigned into two groups, PHG and CGC. This study was conducted at the herbal medicine research house (Rumah Riset Jamu/RRJ) Hortus Medicus and 30 subsites in Central Java and Jogjakarta provinces from July to November 2018. Duration of intervention 28 days. Parameter of efficacy breast milk volume, baby weight, prolactin level and parameter of safety ALT, AST, urea, creatinin were performed at baseline, day 14 and 28. The symptom of side effects also recorded every week.

Results
Breast milk volume and infant’s weight increased at day-14 and 28 in both groups. However, prolactin level in both groups decreased. There were no significant differences of efficacy parameters at baseline in both groups. At three times measurement of ALT, AST, Urea and Ceratinin average levels were within the normal range. About 3–5% mothers experience higher ALT, AST and nausea that can tolerated well. No side effect was found in infants.

Conclusions
PHG and CGC have the equal efficacy and safety as a galactagogue. The optimal used is for 14 days.
The Qurʾān as a Historical Source
Authors: Howard-Johnston James 
Published: April 2024

Abstract
The redirection of the qiblah to the Kaʿbah (Q 2:142-5) is redated from 622, very soon after the hijrah where it is placed in the sīrah, to 628 on the eve of the Prophet’s negotiations with the leaders of Mecca at al-Ḥudaybiyah. It is interpreted as a compromise forced on the Prophet, if he was to reach a settlement with the Quraysh. A corollary was God’s authorisation of pilgrimage in pagan fashion and of animal sacrifice at the Kaʿbah (Q 22: 23-38, Q 5: 2-4). The Kaʿbah was redesignated a monotheist sanctuary, on the grounds of its foundation by Abraham (Q 2:125-7, Q 3:96-8, Q 22:28-9). These sūrahs (and an anomalous late passage in Q 14:35-7) are all late. No earlier sūrah associates Abraham with the Kaʿbah.
Overcoming Strong–Weak Dualisms in Process Organization Studies via Three Theory-Methodology Hybrids
Authors: Pina e Cunha Miguel , Clegg Stewart , Alcadipani Rafael 
Published: April 2024

Abstract
In processual approaches to the sociology of organizations, there are prevalent assumptions differentiating ‘strong’ and ‘weak’ process research. In this paper, we challenge this assumption and suggest a novel, non-dualistic hybrid approach that is methodologically strong-weak. This approach integrates both flux (becoming) and its temporary material instantiations (being), addressing tensions between slow-moving and mid-range elements of process. We argue that both strong and weak process views can contribute to understanding organizing. We explore how their dualism can be overcome methodologically through the combination of time horizons, incorporating substantialist and flux views, as well as proximal and distal perspectives. Using a strong-weak dualism creates an unnecessary theoretical and methodological divide between process as flow and process as material instantiation. We advance three hybrid approaches which we call reifying, liquefying, and embedding. Our contribution consists of strategies to overcome strong-weak dualism for conceptualizing organizations in a sociologically dynamic and holistic manner.
An Argument for Micropsychism: If There is a Conscious Whole, There Must be Conscious Parts
Authors: Rookmaaker Arjen 
Published: April 2024

Abstract
Many philosophers today accept that phenomenal truths cannot be explained in terms of ordinary physical truths. Two possible routes to accounting for consciousness have received much attention: the emergentist route is to accept that ordinary experience is inexplicable in physical terms but that microscopic entities as described in physics nonetheless bring about conscious experience. The second route is to argue that microscopic entities have features not described in physics which can fully explain conscious experience. The view associated with panprotopsychism is that microscopic entities have no phenomenal properties. The view associated with panpsychism is that microscopic entities do have phenomenal properties. In this paper it is argued that if consciousness is extended in space only the latter view is possible. According to this argument for micropsychism, if phenomenal truths are not merely structural, all truths about a whole are truths about its parts plus structural relational truths. If there are phenomenal truths about the whole, this must be because there are phenomenal truths about its parts. It wouldn’t follow that panpsychism is true, since it does not follow that consciousness exists outside the wholes we know to be conscious, but it does follow that emergentism and protopanpsychism are false.
Geographic structure of Chinese dialects: a computational dialectometric approach
Authors: Huang He , Grieve Jack , Jiao Lei , Cai Zhuo 
Published: April 2024

Abstract
Dialect classification is a long-standing issue in Chinese dialectology. Although various theories of Chinese dialect regions have been proposed, most have been limited by similar methodological issues, especially due to their reliance on the subjective analysis of dialect maps both individually and in the aggregate, as well as their focus on phonology over syntax and vocabulary. Consequently, we know relatively little about the geolinguistic underpinnings of Chinese dialect variation. Following a review of previous research in this area, this article presents a theory of Chinese dialect regions based on the first large-scale quantitative analysis of the data from the Linguistic Atlas of Chinese Dialects, which was collected between 2000 and 2008, providing the most up-to-date picture of the full Chinese dialect landscape. We identify and map a hierarchy of 10 major Chinese dialect regions, challenging traditional accounts. In addition, we propose a new theory of Chinese dialect formation to account for our findings.
The crystal structure of (3aS, 4R, 7S, 7aR)-hexahydro-4, 7-methano-1H-isoindole-1, 3-(2H)-dione, C9H11NO2
Authors: Cao Xueli , Guo Xiao 
Published: April 2024

Abstract
C9H11NO2, monoclinic, P21/c (no. 14), a = 11.293(4) Å, b = 6.998(3) Å, c = 10.932(4) Å, β = 104.175(7)°, V = 837.6(5) Å3, Z = 4, R

gt
(F) = 0.0578, wR

ref
(F
2) = 0.1330, T = 296 K.
Crystal structure of 2,5-bis(2,5-dimethoxybenzyl)-3,6-dimethyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione, C26H28N2O6
Authors: Tang Lin-Li , Zeng Fei 
Published: April 2024

Abstract
C26H28N2O6, monoclinic, P21/c (no. 14), a = 15.962(9) Å, b = 14.828(8) Å, c = 9.929(5) Å, β = 93.303°, V = 2346(2) Å3, Z = 4, R
gt(F) = 0.0515, wR
ref(F
2) = 0.1621, T = 296(2) K.
Role of carbon nanotubes, carbon nano-fibres and nano-gels in eliminating pollutants from aqueous solution
Authors: Thayanithi Saranya , Janakiraman Kumar , Alagesan Sridhar , Ramesh Abilesh , Sethuraman Vaidevi , Shanmugasundaram Prema Suriyaraj 
Published: April 2024

Abstract
Pollutants in water bodies is a major threat, which affects both flora and fauna, including humans. The environmental impact on pollutants due to increase in industrialization and growing populations has been increasing every year. The efficient removal of pollutants from aqueous solutions is a significant challenge in environmental remediation. In recent years, the application of nanomaterials has emerged as a promising strategy to address this issue. Of these nanomaterials, carbon nanotubes (CNTs), carbon nanofibers (CNFs), and nano-gels have attracted considerable attention due to their unique properties and their versatile functionalities. In this review, we have discussed about the recent advances in CNTs, CNFs, nanogels in eliminating pollutants from aqueous solution. CNTs possess a notable aspect ratio and demonstrate outstanding mechanical strength, enabling them to effectively adsorb a wide range of contaminants including heavy metals, organic compounds, and gases, CNFs have improved adsorption and catalytic characteristics. These entities exhibit efficacy in the elimination of contaminants from aquatic ecosystems and atmospheric currents, hence aiding in the restoration of polluted settings, and nano-gels, which are composed of cross-linked polymers arranged in three dimensions, offer a flexible framework for the encapsulation of pollutants and the precise delivery of substances. Functionalized nano-gels provide the targeted adsorption of particular contaminants, hence providing customised approaches for the management and mitigation of pollution. The utilisation of nanomaterials holds significant promise in the advancement of water treatment technologies, necessitating the enhancement of their practical applications.
Solid-phase extraction of organophosphates from polluted waters on a matrix-imprinted sorbent
Authors: Alsehli Bandar R. 
Published: April 2024

Abstract
The study aims to synthesize a selective matrix imprinted sorbent for the extraction of parathion and malathion. The structural unit of the polymeric framework was 2-methylpropanoic acid, the intermolecular crosslinker was ethylene glycol dimethacrylate, the polymerization initiator was azobisisobutyronitrile, the porogen was xylene, and the analyte was parathion. The synthesis was carried out under conditions of heating the reaction mixture to 65 °C, after which the matrix was washed with methanol to remove the analyte. For comparison purposes, non-imprinted control polymer was used as a negative control, which was prepared similarly, but without the addition of the analyte. The identification and quantification of organophosphates were performed by gas chromatography, and the morphological characteristics of the sorbents were evaluated by scanning electron microscopy. The optimal buffer for the purification of organophosphates was acetate buffer with a pH of 4; the optimal organic eluent was methanol. The limit of detection for para- and malathion was 0.1 μg/ml; the limit of quantification was 0.3 μg/ml. Linearity in the extraction conditions was observed in the range of 0.1–1 μg/ml for parathion and 0.1–2 μg/ml for malathion. The developed method will enable quick, selective, and cost-effective extraction of organophosphates from various substrates.
A Comprehensive Needs Analysis on Surfing Performance Factors and Training Methodologies
Authors: Monaco Jerry-Thomas , Boergers Richard , Cappaert Thomas , Miller Michael 
Published: April 2024

ABSTRACTIn the past 20 years, surfing has become a popular, non–age-dependent sport that can be performed at most ocean beaches. As it gains exposure, surfers have recognized the importance of physical preparation to enhance their performance and reduce injury risk. This realization has led to an increase in the study and practice of biomechanical and environmental analysis as well as training methodologies for the competitive surfer. As a result, coaches and athletes are including land-based training protocols to maximize the competitive surfer's performance and are designing them based on their surfing schedules. Not only is this training important for competitive surfers, but also for surfers who engage in this sport recreationally. Therefore, the aim was to provide a needs analysis of surfing components such as environmental factors, biomechanical and physiological demands, and current training methods for performance enhancement.
Pseudoproblemas por el uso inapropiado del lenguaje en la construcción del conocimiento en torno al problema de la mente
Authors: Rodríguez Ortiz Angélica María 
Published: April 2024

The dualism of properties and qualia have been inherited problems of the Cartesian theory. Old problems with new vestments that have been overlapped in the speech of cognitive sciences, in special in the one of the philosophy of mind. For some contemporary thinkers the above mentioned 'problems' are within the frameworks of the Metaphysical questions. This article presents advances concerning an analytical research that tries to reveal the genesis of the problem caused by the inadequate use of language, in order to show that such questions in the long run are only pseudoproblems. Problems of linguistic and logical order disguised with metaphysical apparel. In the first part of the writing the speech that gives origin to the problem will be analyzed, later the Cartesian speech will be checked - being this the official doctrine that inherits the problem to the philosophy of the mind- they will present the reasons for which it affirms that these problems are not more than errors inherited by the use of language. Finally, they will present in a brief way how the eliminative and emergent positions of Dennett and Searle there are no really overcoming of the dualism as they sustain it.