bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bidentate and Tetradentate β‐Aminovinyl Trifluoromethylated Ketones and Their Copper(II) Complexes: Synthesis, Characterization and Redox Chemistry
Authors: Chopin Nicolas , Médebielle Maurice , Pilet Guillaume 
Published: January 2012

AbstractNew polyfunctional bidentate and tetradentate trifluoromethylated enaminone ligands that bear redox‐active and photosensitive moieties were synthesized in moderate to good yields and their coordination chemistry with copper(II) was examined. The crystal structures revealed the formation of mononuclear CuII complexes with all ligands, where the metal ion is located in almost perfect to distorted square planar environments. The deviation from an ideal square plane influences the redox potentials of the metal centre within the complex as demonstrated by cyclic voltammetry. For all the complexes, a stable CuI species was evidenced by a quasireversible reduction step at potentials from –0.48 to –1.08 V (potential standards E0), but the most stable CuI species originated from the CuII complex with the tetradentate ligand. UV/Vis absorption spectra revealed no major differences between the ligands and their CuII complexes.
The varying meaning of forgiveness: Relationship closeness moderates how forgiveness affects feelings of justice
Authors: Wenzel Michael , Okimoto Tyler G. 
Published: January 2012

AbstractPsychological research has repeatedly shown that victims are more likely to forgive socially close than distant others, but little research has addressed the question whether forgiveness in these two cases actually has the same psychological meaning. As one approach to this issue, the present research investigates how acts of forgiveness aid the restoration of victims' justice feelings through different processes, depending on the closeness of their relationship to the offender. In two studies (Study 1 using a scenario method, Study 2 an autobiographical recall), the victim's perceptions of value consensus with the offender mediated justice‐restoring effects of forgiveness expressed towards a close offender, whereas feelings of status/power mediated justice‐restoring effects of forgiveness expressed towards a distant offender. Copyright © 2012 John Wiley & Sons, Ltd.
Ion Selective Electrode for Dopamine Based on a Molecularly Imprinted Polymer
Authors: Pesavento M. , D'Agostino G. , Biesuz R. , Alberti G. , Profumo A. 
Published: January 2012

AbstractAn all‐solid‐state ISE for dopamine (DAHCl) has been developed based on a screen printed graphite electrode modified with a multiwalled carbon nanotubes layer as an ion to electron transducer. The selective membrane is an acrylic polymer molecularly imprinted with the ion of interest (MIP). The polymer is made up of methacrylic acid as functional monomer and ethyleneglycole dimethacrylate as cross linker. The polymerization at 75 °C in the presence of AIBN as initiator was carried out in situ, directly over the CNT‐modified screen printed graphite. The specific site obtained after polymerization and template elution can be considered as the ionophore, and the carboxylic groups as the cation exchanger groups, similarly to the usual ISE membrane. The specificity of the electrode was evaluated by voltammetric methods, and was very good. The potential of the electrode, measured against a double junction Ag/AgCl/KCl (sat.), linearly increases with the dopamine concentration at concentration higher than 10−4 M, but only in salt solution at least 0.1 M. The sensibility was less than nernstian. Not any potential increase was found for the electrode modified with not imprinted polymer (NIP) at the same conditions. The effect of ions in solution was particularly considered.
Determination of Nifuroxazide by Flow Injection Linear Adsorptive Stripping Voltammetry on a Screen‐Printed Carbon Nanofiber Modified Electrode
Authors: Mozo J. D. , Carbajo J. , Sturm J. C. , Núñez‐Vergara L. J. , Salgado P. , Squella J. A. 
Published: January 2012

AbstractA new, sensitive, reproducible and easy‐to‐use flow‐injection method for determining nifuroxazide based on adsorptive stripping linear sweep voltammetry over screen‐printed carbon electrodes is presented. The presented method is the first report of Nifuroxazide determination using a screen printed electrode and FIA and it is useful for pharmaceutical quality control, specifically, it could be adopted as an effective portable tool for on the shelf quality control at pharmacies.Limits of quantification (LOQ) and detection (LOD) as low as 42 and 10 ng/mL, respectively, were found. An average recovery of 100.7 %, and a standard deviation of 2.5 % indicates acceptable accuracy and precision validating the proposed method.
Analytical solutions and validation of electric field and dielectrophoretic force in a bio‐microfluidic channel
Authors: Nerguizian Vahé , Alazzam Anas , Roman Dacian , Stiharu Ion , Burnier Miguel 
Published: January 2012

AbstractIn a microbiological device, cell or particle manipulation and characterization require the use of electric field on different electrodes in several configurations and shapes. To efficiently design microelectrodes within a microfluidic channel for dielectrophoresis focusing, manipulation and characterization of cells, the designer will seek the exact distribution of the electric potential, electric field and hence dielectrophoresis force exerted on the cell within the microdevice. In this paper we describe the approach attaining the analytical solution of the dielectrophoretic force expression within a microchannel with parallel facing same size electrodes present on the two faces of channel substrates, with opposite voltages on the pair electrodes. Simple Fourier series mathematical expressions are derived for electric potential, electric field and dielectric force between two distant finite‐size electrodes. Excellent agreement is found by comparing the analytical results calculated using MATLAB™ with numerical ones obtained by Comsol. This analytical result can help the designer to perform simple design parametric analysis. Bio‐microdevices are also designed and fabricated to illustrate the theoretical solution results with the experimental data. Experiments with red blood cells show the dielectrophoretic force contour plots of the analytical data matched to the experimental results.
Arbitrary single primer amplification of trace DNA substrates yields sequence content profiles that are discriminatory and reproducible
Authors: Waters James M. , Eariss Graham , Yeadon P. Jane , Kirkbride K. Paul , Burgoyne Leigh A. , Catcheside David E. A. 
Published: January 2012

AbstractSingle primer amplification is shown to yield a DNA profile that is reproducible when based on the sequence content of the amplicons rather than on the pattern of length polymorphism. The sequence‐based profile increases in reliability with increasing numbers of cycles of amplification. This process uses an arbitrarily chosen primer and a low initial annealing temperature in order to amplify sequences from the whole metagenome present in a sample that may contain only trace DNA, and a large number of cycles to select subsets of sequences based on variable amplification efficiency. Using arrays, we demonstrate the utility and limitations of this approach for profiling the large metagenomes typical of soils and the trace DNA present in drug seizures. We suggest that this type of profiling will be most effective once next‐generation sequencing and advanced sequence analysis becomes routine.
Mutation scanning‐based analysis of anisakid larvae from Sillago flindersi from Bass Strait, Australia
Authors: Jabbar Abdul , Khoon Avalene T. W. , Hui Teo X. , Schaeffner Bjoern C. , Jex Aaron R. , Nolan Matthew J. , Lopata Andreas , Gasser Robin B. , Beveridge Ian 
Published: January 2012

AbstractAnisakidosis is an important fish‐borne disease caused by the larvae of anisakid nematodes, which affects humans and a range of other animals. The accurate identification of members of this nematode group is central to investigating the epidemiology of the parasites and in the surveillance and control of anisakidosis. It is now well known that morphological identification alone does not allow specific identification, particularly of larval stages. To better understand the epidemiology of anisakid nematodes in southern Australian fishes and the potential risks posed to human health, a survey of 50 specimens of the commercially important fish, Sillago flindersi, from Bass Strait, Australia was conducted. We characterised anisakid larvae by PCR‐coupled mutation scanning, sequencing and phylogenetic analyses of the first and second internal transcribed spacers (ITS‐1 and ITS‐2) of nuclear ribosomal DNA. This study revealed that 92% of the S. flindersi examined were infected with anisakids (n=194), which were represented by seven genotypes. Phylogenetic analyses of the genotypes defined herein, together with reference sequence for Anisakis pegreffii and Hysterothylacium sp. from public databases (i.e. GenBank), revealed the presence of A. pegreffii (n=24), Hysterothylacium larval type IV (n=90) and Hysterothylacium larval type VIII (n=80) in S. flindersi. Thus, the PCR‐coupled mutation scanning approach employed herein is an effective tool for the genetic characterisation of anisakid nematodes for diagnostic and analytical purposes (nucleotide sequences reported in this paper are available in the GenBank database under accession nos. JN631796‐809).
Stability of amyloid‐β peptides in plasma and serum
Authors: Bibl Mirko , Welge Volker , Esselmann Hermann , Wiltfang Jens 
Published: January 2012

AbstractPlasma amyloid‐β peptide (Aβ) levels have been suggested as a biomarker candidate for detecting incipient AD. Aβ peptides are known to be sensitive to distinct preanalytical sample handling, which calls for standardised preanalytical procedures. We investigated serum and plasma samples of 19 patients with no clinical signs of dementia for different preanalytical sample handlings. Both serum and plasma were analysed by the one‐dimensional Aβ‐SDS‐PAGE/immunoblot, either immediately or after storage at room temperature for 24 and 48 h, respectively. The panel of Aβ1–37/38/39/40/42 and Aβ2–40 was evaluated. In both analytical matrices, sample storage led to a significant loss of measurable peptide levels. This effect was most pronounced during the first 24 h of storage and stronger in serum than in plasma. There were no significant differences between the distinct analysed Aβ peptide species regarding these results. The ratios of peptides (e.g. Aβ1–42/Aβ1–40 and Aβ1–42/Aβ1–38) displayed a higher stability under the influence of storage than each single peptide. In conclusion, plasma may be more appropriate than serum for analysing Aβ peptides for routine application. At least, the analysis should be done within 24 h and peptide ratios should be created to minimise artificial results.
Health monitoring of fluid dampers for vibration control of structures: experimental investigation
Authors: Konstantinidis Dimitrios , Makris Nicos , Kelly James M. 
Published: January 2012

SUMMARYThis paper presents results from a comprehensive experimental program on medium‐size and large‐size fluid dampers in an effort to extract their force output during cyclic loading by simply measuring the strain on the damper housing and the end‐spacer of the damper. The paper first discusses the stress path within the damper and, subsequently via the use of linear elasticity, shows that the experimental data obtained with commercially available strain gauges yield a force output of the damper that is in good agreement with the readings from the load cell. This comparison is achieved via the use of a position and velocity transducer, which combines good accuracy together with robust performance in a marine environment. The paper then examines the performance of a portable data acquisition system that can be used to collect and transmit data from a damper installed on a bridge to a nearby location (order of a km) where data are collected via either a wired or a wireless Local Area Network (LAN). Alternatively, the data may be transmitted to any remote location via mobile telecommunication networks; however, this requires leased telephone lines. The data show that the proposed arrangement is promising for monitoring in situ the force output of fluid dampers and detecting possible loss of their energy dissipation capability. Copyright © 2012 John Wiley & Sons, Ltd.
Sediment mobility and bed armoring in the St Clair River: insights from hydrodynamic modeling
Authors: Liu Xiaofeng , Parker Gary , Czuba Jonathan A. , Oberg Kevin , Mier Jose M. , Best James L. , Parsons Daniel R. , Ashmore Peter , Krishnappan Bommanna G. , Garcia Marcelo H. 
Published: January 2012

ABSTRACTThe lake levels in Lake Michigan‐Huron have recently fallen to near historical lows, as has the elevation difference between Lake Michigan‐Huron compared to Lake Erie. This decline in lake levels has the potential to cause detrimental impacts on the lake ecosystems, together with social and economic impacts on communities in the entire Great Lakes region. Results from past work suggest that morphological changes in the St Clair River, which is the only natural outlet for Lake Michigan‐Huron, could be an appreciable factor in the recent trends of lake level decline. A key research question is whether bed erosion within the river has caused an increase in water conveyance, therefore, contributed to the falling lake level. In this paper, a numerical modeling approach with field data is used to investigate the possibility of sediment movement in the St Clair River and assess the likelihood of morphological change under the current flow regime. A two‐dimensional numerical model was used to study flow structure, bed shear stress, and sediment mobility/armoring over a range of flow discharges. Boundary conditions for the numerical model were provided by detailed field measurements that included high‐resolution bathymetry and three‐dimensional flow velocities. The results indicate that, without considering other effects, under the current range of flow conditions, the shear stresses produced by the river flow are too low to transport most of the coarse bed sediment within the reach and are too low to cause substantial bed erosion or bed scour. However, the detailed maps of the bed show mobile bedforms in the upper St Clair River that are indicative of sediment transport. Relatively high shear stresses near a constriction at the upstream end of the river and at channel bends could cause local scour and deposition. Ship‐induced propeller wake erosion also is a likely cause of sediment movement in the entire reach. Other factors that may promote sediment movement, such as ice cover and dredging in the lower river, require further investigation. Copyright © 2012 John Wiley & Sons, Ltd.
Do alternate bars affect sediment transport and flow resistance in gravel‐bed rivers?
Authors: Francalanci Simona , Solari Luca , Toffolon Marco , Parker Gary 
Published: January 2012

ABSTRACTIn natural gravel‐bed streams, the complex topography of the bed can cause variation of flow resistance and sediment transport. Previous studies have shown that in addition to grain resistance (skin friction), flow resistance is also caused by bank roughness, channel bars, bed undulations and channel curvature. Sediment transport is similarly influenced by the complex topography, and the transport rate can vary spatially. A three‐dimensional (3D) numerical model was used to generate a detailed description of the flow and bedload transport fields in gravel‐bed rivers. Here we quantify the reach‐averaged hydraulic resistance and sediment transport regime that prevails when self‐formed alternate river bars are present, and compare with the regime that would prevail were no bars are present. We do this by comparing the results of (i) a 3D morphodynamic model in which bars form as a consequence of flow‐bed interaction and (ii) an ‘equivalent’ one‐dimensional (1D) case, which refers to flat bed conditions, but otherwise corresponding to identical average velocity and bed slope. The 3D numerical model is applied to generate different bed topographies of alternate bars at regime morphological equilibrium, then extended to non‐equilibrium conditions for decreasing shear stress within a sensitivity analysis context. The contribution of grain resistance is estimated with the local values of the bed shear stress, while bar resistance results from the overall deviation of the flow field from that occurring in the flat bed configuration. The local sediment transport in both the longitudinal and transverse directions is computed with the local Shields stress and local bed inclination. The calculations result in a method for correcting 1D models to account for the total sediment transport and resistance in a cross‐section due to 3D effects of alternate bars. We term the resulting relations ‘morphologically averaged’ sediment transport and resistance equations. Copyright © 2012 John Wiley & Sons, Ltd.
Characteristics of beaver ponds on deltas in a mountain environment
Authors: Butler David R. 
Published: January 2012

ABSTRACTMany beaver ponds in the Rocky Mountains, that have been described in the literature, are in‐channel ponds that are relatively small and short‐lived. This paper describes floodplain beaver ponds on low‐gradient deltas in glacial finger lakes in Glacier National Park, Montana. These ponds are distinctly larger, probably fed by hyporheic flow, and stable and long‐lived. Ponds examined were, with one exception, 44 years old. Glacial discharge is present in each valley where beaver ponds occupy low‐gradient deltas, and this discharge likely sustains pond water level over the course of the summer. As glaciers recede and disappear, deltaic beaver ponds dependent on hyporheic flow may be negatively affected. Copyright © 2012 John Wiley & Sons, Ltd.
High spatial resolution mapping of surface velocities and depths for shallow overland flow
Authors: Legout C. , Darboux F. , Nédélec Y. , Hauet A. , Esteves M. , Renaux B. , Denis H. , Cordier S. 
Published: January 2012

ABSTRACTPoint measurements of flow rate, depth or velocity are not sufficient to validate overland flow models, particularly when the interaction of the water with the soil surface creates a complex flow geometry. In this study, we present the coupling of two techniques obtaining spatial data of flow depths and surface velocity measurements for water depths as low as 1 mm. Overland flow experiments were performed in the laboratory at various flow rates and slopes on two surfaces. The first surface was 120 cm by 120 cm showing three undulations of sinusoidal shape with an amplitude of 1 cm and a wavelength of 20 cm, while the second was a 60 cm by 60 cm moulded reproduction of a seedbed with aggregates up to 2 cm in size. Large scale particle image velocimetry (LSPIV) was used for velocity measurements with a sub‐centimetre spatial resolution. An instantaneous‐profile laser scanner was used to map flow depths with a sub‐millimetre spatial resolution. A sensitivity analysis of the image processing of the LSPIV showed good robustness of the method. Comparison with measurements performed with hot film anemometer and salt velocity gauge showed that LSPIV surface velocities were representative of the flow. Water depths measured with the laser scanner were also in good agreement with single‐point measurements performed with a dial indicator. Spatially‐distributed flow rates could be computed by combining both presented techniques with a mean relative error less than 20%. Copyright © 2012 John Wiley & Sons, Ltd.
Large eddy simulation of turbulent shallow water flows using multi‐relaxation‐time lattice Boltzmann model
Authors: Liu Haifei , Li Min , Shu Anping 
Published: January 2012

SUMMARYIn this paper, the standard Smagorinsky's algorithm is embedded into the multiple relaxation time (MRT) lattice Boltzmann model (LBM) for large eddy simulation (LES) of turbulent shallow water flows (MRT‐LABSWETM). The model is based on the two‐dimensional nonlinear shallow water equations, giving the depth‐averaged features. It is verified by applying the model in three typical cases in engineering with turbulence: (i) the flow around a square cylinder, (ii) plane cavity flow, and (iii) flows in a junction of 90°. The results obtained by the MRT‐LABSWETM are compared with BGK‐LABSWETM results and experimental data. The objectives of this study are to validate the MRT‐LABSWETM in a turbulence simulation and perform a comparative analysis between the results of BGK‐LABSWETM and MRT‐LABSWETM. Copyright © 2012 John Wiley & Sons, Ltd.
Level V in therapeutic neck dissections for papillary thyroid carcinoma
Authors: Khafif Avi , Medina Jesus E. , Robbins K.Thomas , Silver Carl E. , Weber Randal S. , Rinaldo Alessandra , Owen Randall P. , Shaha Ashok R. , Ferlito Alfio 
Published: January 2012

AbstractNeck dissection for papillary thyroid carcinoma (PTC) is the standard of care for patients with clinical evidence of regional metastases. However, the extent of neck dissection is debatable. The purpose of the current study was to develop evidence‐based recommendations for when to include level V, or 1 of its sublevels, among patients with PTC undergoing neck dissection. A literature review of all studies evaluating the occurrence of metastases in level V in patients with regional metastases from PTC undergoing neck dissection was performed. Occurrence of metastases at level V is low in most series (5% to 10%), although a wide range was noticed. In cases in which metastases were found at level V, they occurred almost exclusively at sublevel VB. Sublevel VA was rarely, if ever, involved with metastatic lymph nodes. However, only recently have investigators begun to specify which sublevels of level V are at risk. Therapeutic dissection of level V is indicated when there is clinical evidence of disease involving this zone. Elective dissection of sublevel VB is indicated when there is involvement of level IV, or possibly multiple nodes at levels II and III. Under these circumstances, dissection of sublevel VB is indicated but sublevel VA may be spared. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
High prevalence of vitamin D insufficiency in patients with head and neck cancer at diagnosis
Authors: Orell–Kotikangas Helena , Schwab Ursula , Österlund Pia , Saarilahti Kauko , Mäkitie Outi , Mäkitie Antti A. 
Published: January 2012

AbstractBackgroundLow serum levels of vitamin D, measured as serum 25‐hydroxy‐vitamin D (S‐25‐OHD), have been observed in several cancers.MethodsSixty‐five adult patients with head and neck cancer, 50 men, median age 61 years (range, 33–77 years), were enrolled in this prospective cohort study. Concentrations of S‐25‐OHD and plasma calcium (Ca) and phosphate (Pi) were measured before cancer treatment.ResultsThe mean S‐25‐OHD was 42.0 (SD 22) nmol/L. Hypovitaminosis D (37.5–50 nmol/L) was found in 20% of the patients and vitamin D deficiency (<37.5 nmol/L) in 45% of the patients. No seasonal variation was seen. Subnormal plasma Ca and Pi levels were found in 11% and 9% of the patients, respectively.ConclusionSubnormal vitamin D levels were found in a significant proportion of the patients. Because vitamin D deficiency may pose these patients to increased risk of therapy‐related morbidity, special attention should be paid to correction of this nutritional deficiency. © 2012 Wiley Periodicals, Inc. Head Neck, 2012