bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 outbreaks in residential aged care facilities: an agent-based modeling study
Authors: McAndrew Fenella , Sacks-Davis Rachel , Abeysuriya Romesh G. , Delport Dominic , West Daniel , Parta Indra , Majumdar Suman , Hellard Margaret , Scott Nick 
Published: May 2024

IntroductionA disproportionate number of COVID-19 deaths occur in Residential Aged Care Facilities (RACFs), where better evidence is needed to target COVID-19 interventions to prevent mortality. This study used an agent-based model to assess the role of community prevalence, vaccination strategies, and non-pharmaceutical interventions (NPIs) on COVID-19 outcomes in RACFs in Victoria, Australia.MethodsThe model simulated outbreaks in RACFs over time, and was calibrated to distributions for outbreak size, outbreak duration, and case fatality rate in Victorian RACFs over 2022. The number of incursions to RACFs per day were estimated to fit total deaths and diagnoses over time and community prevalence.Total infections, diagnoses, and deaths in RACFs were estimated over July 2023–June 2024 under scenarios of different: community epidemic wave assumptions (magnitude and frequency); RACF vaccination strategies (6-monthly, 12-monthly, no further vaccines); additional non-pharmaceutical interventions (10, 25, 50% efficacy); and reduction in incursions (30% or 60%).ResultsTotal RACF outcomes were proportional to cumulative community infections and incursion rates, suggesting potential for strategic visitation/staff policies or community-based interventions to reduce deaths. Recency of vaccination when epidemic waves occurred was critical; compared with 6-monthly boosters, 12-monthly boosters had approximately 1.2 times more deaths and no further boosters had approximately 1.6 times more deaths over July 2023–June 2024. Additional NPIs, even with only 10–25% efficacy, could lead to a 13–31% reduction in deaths in RACFs.ConclusionFuture community epidemic wave patterns are unknown but will be major drivers of outcomes in RACFs. Maintaining high coverage of recent vaccination, minimizing incursions, and increasing NPIs can have a major impact on cumulative infections and deaths.
Fine particulate matter-sudden death association modified by ventricular hypertrophy and inflammation: a case-crossover study
Authors: Rappazzo Kristen M. , Egerstrom Nicole M. , Wu Jianyong , Capone Alia B. , Joodi Golsa , Keen Susan , Cascio Wayne E. , Simpson Ross J. 
Published: May 2024

BackgroundSudden death accounts for approximately 10% of deaths among working-age adults and is associated with poor air quality. Objectives: To identify high-risk groups and potential modifiers and mediators of risk, we explored previously established associations between fine particulate matter (PM2.5) and sudden death stratified by potential risk factors.MethodsSudden death victims in Wake County, NC, from 1 March 2013 to 28 February 2015 were identified by screening Emergency Medical Systems reports and adjudicated (n = 399). Daily PM2.5 concentrations for Wake County from the Air Quality Data Mart were linked to event and control periods. Potential modifiers included greenspace metrics, clinical conditions, left ventricular hypertrophy (LVH), and neutrophil-to-lymphocyte ratio (NLR). Using a case-crossover design, conditional logistic regression estimated the OR (95%CI) for sudden death for a 5 μg/m3 increase in PM2.5 with a 1-day lag, adjusted for temperature and humidity, across risk factor strata.ResultsIndividuals having LVH or an NLR above 2.5 had PM2.5 associations of greater magnitude than those without [with LVH OR: 1.90 (1.04, 3.50); NLR &gt; 2.5: 1.25 (0.89, 1.76)]. PM2.5 was generally less impactful for individuals living in areas with higher levels of greenspace.ConclusionLVH and inflammation may be the final step in the causal pathway whereby poor air quality and traditional risk factors trigger arrhythmia or myocardial ischemia and sudden death. The combination of statistical evidence with clinical knowledge can inform medical providers of underlying risks for their patients generally, while our findings here may help guide interventions to mitigate the incidence of sudden death.
Efficacy of telemedicine intervention in the self-management of patients with type 2 diabetes: a systematic review and meta-analysis
Authors: Liu Fengzhao , Li Jixin , Li Xiangyu , Yang Zhenyu , Wang Wenru , Zhao Lijuan , Wu Tao , Huang Chengcheng , Xu Yunsheng 
Published: May 2024

PurposeWe aimed to report the latest and largest pooled analyses and evidence updates to assess the effectiveness of telemedicine interventions for self-management (DSM) in patients with type 2 diabetes mellitus (T2DM).MethodsA systematic literature search was conducted using PubMed, Cochrane, Embase, and Web of Science in December 2023. We included randomized controlled trials (RCTs) of adults (≥18 years of age) diagnosed with T2DM where the intervention was the application of telemedicine. The Cochrane Risk of Bias Assessment was used to evaluate quality. The study’s main outcome indicators were glycosylated hemoglobin (HbA1c) and diabetes self-management (DSM) capacity.ResultsA total of 17 eligible articles, comprising 20 studies and 1,456 patients (734 in the intervention group and 722 in the control group), were included in the evidence synthesis. The baseline characteristics of both groups were similar in all outcomes. Comprehensive analyses showed post-intervention decreases in HbA1c, 2-h postprandial glucose, systolic and diastolic blood pressure, increases in Diabetes Self- Care activities, DSM competencies based on dietary and medication adherence, and improvements in overall DSM scores, all of which were statistically significant. While no statistically significant differences were observed in body mass index, lipids, and other DSM dimensions. Based on subgroup analyses, app-based experimental interventions targeting under 60 years old populations in Asia and North America were found to be more effective and less heterogeneity in the short term (&lt;6 months of intervention).ConclusionTelemedicine interventions may assist patients with T2DM in enhancing their DSM and improving their HbA1c levels. Clinician can use various telemedicine interventions to enhance DSM in T2DM patients, considering local circumstances.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42024508522.
Varroa destructor economic injury levels and pathogens associated with colony losses in Western Canada
Authors: Morfin Nuria , Foster Leonard J. , Guzman-Novoa Ernesto , Van Westendorp Paul , Currie Robert W. , Higo Heather 
Published: May 2024

IntroductionThe honey bee parasitic mite, Varroa destructor, is considered the main factor associated with winter colony losses. To control this mite, beekeepers must implement Integrated Pest Management (IPM) strategies. An effective IPM strategy is based on timely monitoring of mite levels to treat the colonies when the mites reach an economic threshold and before they grow to damaging levels (economic injury level). Additionally, concerns have been raised about the possible interaction between V. destructor and other stressors; stressors acting additively or synergistically may lead to high colony mortality.MethodologyVarroa destructor levels were recorded in colonies from five regions of British Columbia, Canada: Lower Mainland, Kootenay, Okanagan, Cariboo, and Peace. Mite levels were analyzed for associations with colony strength and mortality, as well as with other pathogens that were identified using total RNA sequencing.ResultsThe Kootenay and Lower Mainland regions had the highest V. destructor levels in the fall (3.38±0.65 and 2.51±0.57, respectively) followed by the Okanagan (1.54±0.36), Cariboo (1.31±0.39), and Peace (0.66±0.25) regions. The Peace region had a significantly lower proportion of dead colonies than the other regions. Varroa destructor levels in the fall significantly predicted odds of colony mortality in the spring. Colonies with ≥ 1% mite infestation in the fall (August) had a significantly higher mortality rate (p=0.005) compared to colonies with &lt;1% mite levels. Therefore, treatment is recommended above that threshold. Also, deformed wing virus-B levels were 8.4 times higher than those of deformed wing virus-A variant in all the regions and were highest in the Kootenay region, which also had the highest rate of colony losses. Lastly, Malpighamoeba mellificae and Nosema (Vairimorpha) apis transcripts were identified along with other pathogens that deserve further investigation, including Apis mellifera filamentous virus, Apis rhabdovirus, Lake Sinai virus, Varroa tymo-like, and Apis mellifera solinvivirus 1.DiscussionThe dynamic nature of host-pathogen interactions requires frequent pathogen surveillance to determine the prevalence and levels of parasitic mites and associated infectious diseases, and their impact on honey bee health, not only in the regions of this study, but globally. Nevertheless, more studies are needed to determine the nature of the type of interaction between the identified pathogens and V. destructor. Also, more research is needed to evaluate their potential impact on colony survival, to provide accurate mite and disease control recommendations to beekeepers.
Long-term follow-up results of prostate capsule-sparing and nerve-sparing radical cystectomy with neobladder: a single-center retrospective analysis
Authors: Zhu Zaisheng , Zhu Yiyi , Shi Hongqi , Zhou Penfei , Xue Yadong , Hu Shengye 
Published: May 2024

ObjectiveThis study aims to investigate and analyze the feasibility, oncological outcomes, functional efficacy, and complications with the prostatic capsule sparing (PCS) as well as the nerve sparing (NS) in radical cystectomy for bladder cancer.Patients and methodsBetween January 2007 and December 2021, 67 total cystectomies with PCS and 54 with NS were performed at our institution. The inclusion criteria for PCS were as follows: proactive, fully informed patient consent; negative transurethral resection of the bladder neck; normal prostate-specific antigen (PSA) level &lt; 4 ng/dL; and normal transrectal ultrasonography with biopsy of any suspicious nodes. Patients received complete oncological and functional follow-ups. The Kaplan-Meier method was utilized to characterize survival outcomes after surgery.ResultsThe median follow-up times for PCS and NS were 144 and 122 months, respectively. Cumulative survival estimated the 5- and 10-years cancer-specific survival were 93.0% and 88.7% for the PCS group and 79.7% and 79.6% for the NS group, respectively (p = 0.123). In terms of function, the daytime urinary control at 3, 6, and 12 months postoperatively was 80.60%, 97.01%, and 100% in the PCS group, and 53.70%, 85.19%, and 94.44% in the NS group, respectively (p = 0.002, 0.023, and 0.100); and nocturnal urinary control was 62.69%, 94.03%, and 98.51% in the PCS group, and 40.74%, 72.22%, and 87.04% in the NS group, respectively (p = 0.016, 0.001, and 0.022). The erectile function recovery revealed that 62.69% and 40.74% of patients returned to preoperative levels (International Index of Erectile Function (IIEF)-5 score ≥ 15) in the PCS and NS groups, respectively (p = 0.016). Considering complications within 30 days after surgery, 4.48% and 7.69% patients had Clavien ≥ III complications in the PCS and NS groups, respectively (p = 0.700).ConclusionThe PCS provides better restored urinary control and sexual function than the NS technique and does not affect oncological outcomes. However, PCS is prone to bladder-neck obstruction complications and requires closer long-term follow-up.
Acesso precoce à fisioterapia após a alta hospitalar de uma Unidade de AVC em Joinville
Authors: Preis Sabrina , Eckermann da Silva Helton , Klitzke Fabiane Maria , Beiersdorff Klug Adriana , Engster Maria Paula 
Published: May 2024

Objetivo. Caracterizar o acesso à reabilitação após AVC na rede pública da região de saúde de Joinville, as barreiras e facilitadores encontrados pelos usuários. Método. Estudo observacional, longitudinal e prospectivo realizado na Unidade de AVC do Hospital Municipal São José entre abril e julho de 2023. A amostra incluiu pacientes com AVC, com idade ≥18 anos, indicados para reabilitação fisioterapêutica e que assinaram o TCLE. Os participantes foram avaliados com um questionário sociodemográfico e clínico, além de um questionário de acesso após 30 dias da alta hospitalar. Resultados. Foram incluídos 45 pacientes, com idade média de 65,12±13,47 anos, principalmente do município de Joinville (67,5%). A maioria tinha fatores de risco como hipertensão (70,0%) e diabetes (52,5%). Após a alta, 65,0% iniciaram a reabilitação em até 30 dias, com média de 8,5±7,7 dias na região e 14,5±9,8 dias em Joinville. A condução própria foi um facilitador (61,5%), enquanto a fila de espera nas clínicas do SUS foi a principal barreira (35,0%). Conclusões. O acesso à reabilitação foi efetivo para mais da metade dos pacientes em até 30 dias, com indicadores similares ou superiores à literatura brasileira. Facilitadores incluíram protocolos estabelecidos, equipe multiprofissional, estratégias de educação em saúde, realização de encaminhamentos na alta e posse de condução própria. A principal barreira foi a fila de espera nos serviços públicos, impossibilitando o acesso precoce e levando os usuários e familiares a buscarem serviços particulares.
A Prospective Observational Study to Evaluate Safety and Efficacy of Intraarticular Administration of Triamcinolone Acetonidein Knee Osteoarthritis in A Tertiary Care Hospital
Authors: P Lazaru , J N. Suresh Kumar , D Chenna Reddy , B Aliveli Bai , Ch Naga Nandini , G K.S Prathyusha , P Jyothirmai V , S Sowmya 
Published: May 2024

Objective: Osteoarthritis is a chronic disease marked by cartilage deterioration, affecting millions globally. Although incurable, it can be managed with adjuvant therapy. This study aims to assess the safety and efficacy of intra-articular Triamcinolone acetonide in knee OA, a corticosteroid used for OA, Rheumatoid arthritis, gouty arthritis, and skin disorders.
Methods: In a prospective observational study with 120 participants, pain severity was evaluated using numerical pain rating and KL-grade scales, while joint space narrowing was assessed via X-ray reports. Subjects were categorized by severity and prescribed intra-articular Triamcinolone acetonide, analgesics, NSAIDs, PPIs, and supplements. They were monitored for pain reduction.
Results: Pain scores were evaluated using NPRS and KL-grade scale: initially, severe pain affected 4.1% (n=5), moderate 86.6% (n=104), mild 9.1% (n=11). After three follow-ups over 6 months, severe pain decreased to 1.6% (n=2), moderate to 84.1% (n=101), and mild increased to 14.1% (n=17).
Conclusion: Our study concludes that intra-articular triamcinolone acetonide, combined with oral and topical analgesics, PPIs, nutritional, and vitamin supplements, is safer and more effective for knee OA, improving patient quality of life, reducing disease severity, prescription charges, and adverse drug reactions.
Ethnomathematics of Lahbako Dance Movement In The Perspective Of Mathematical Literacy Of Geometry Concept
Authors: Wardah Nabilahdhia Rahayu Prima , Panglipur Indah Rahayu , Putra Eric Dwi 
Published: May 2024

Movement in a dance is a visual symbol full of meaning conveyed to be accepted by dance lovers from the whole dance performed. The selection of dance movements is related to the mathematical concept of illustrating its meaning (ethnomathematics). In addition, there is a mathematical literacy process of geometry concepts revealed in dance movements. This becomes a meaningful symbol that becomes a wealth of dance movements that are increasingly interesting to present. The purpose of this research is to identify the ethnomathematics of lahbako dance in the perspective of mathematical literacy of geometry concepts. qualitative research with a descriptive approach to explain the data and its discussion. Data collection methods of interviews, observation, and documentation with data validity test source triangulation. Subjects 2 people from Arutala dance studio and Hastarini. The results obtained are dance movements that come from different habits and interpretations of dancers but the actual meaning of the movements is the same. Ethnomathematics in lahbako dance successfully illustrates the meaning of the movements conveyed in lahbako dance through hand, finger, foot, and body movements that modify into lines, acute and obtuse angles, and triangular and rectangular fields. The mathematical literacy perspective of the geometric concepts of lines, angles, and fields is visualized conceptually, the application of real contexts of daily life, geometric thinking, and the delivery of mathematical language helps in illustrating the message conveyed in a lahbako dance, namely the activities of tobacco farmers. Further research recommendations for dance movements that jump or repeatedly back and forth and the count used by dancers in each movement.
Case Study: Learning Material-based on Model-Eliciting Activities to Enhance Problem Solving Abilities and Self Confident
Authors: Berlian M Ridho Ratu , Hapizah Hapizah , Susanti Ely 
Published: May 2024

This development research aims to describe a valid and practical learning material-based on Model-Eliciting Activities (MEAs) and its effect on problem-solving abilities and self-confidence. The subjects of this research were 36 students grade 10th at MA Negeri 1 OKU Timur. The type of research used is design research with a development study type. The instrument used test, questionnaire, walkthrough, and interview. The data analysis used descriptive techniques. The validity of learning material-based on the model eliciting activities (MEAs) is demonstrated from the results of the assessment carried out by the validator at the expert reviews stage where researchers will receive suggestions and comments in terms of content, construct, and language as well as comments and suggestions at the one-to-one stage. Meanwhile, practicality can be seen from the results at the small group stage. Learning material-based on model eliciting activities (MEAs) model has a potential effect on students' problem-solving abilities and self-confidence as seen from the results of the analysis of students' answers at the field test stage. Based on the results of the analysis of problem solving ability test scores, 29 students (80.56%) were in the positive category, while 7 students (19.44%) were negative or had not reached the minimum criteria for completing the test results. And also seen from the results of the analysis of students' answers to the self-confidence questionnaire, which shows that 17% of students have very positive self-confidence, 58% of students have positive self-confidence, 25% of students have negative self-confidence
Limitaciones Sociales del Adulto Mayor y su Influencia en el Envejecimiento Activo, Estado de México, 2023
Authors: Guzmán Caballero Enid Asvany , Martínez Sánchez Neydhelin , Gómez Aguilar Berenice , Álvarez Hernández Helí Jesset 
Published: May 2024

La población adulta mayor en situación de vulnerabilidad social disminuyó del 33.6% al 26.9% entre 2008 y 2018, pero la vulnerabilidad económica aumentó del 4.3% al 8.3% (Coneval, 2018). Objetivo. determinar las limitaciones sociales de los adultos mayores que influyen en su búsqueda de envejecimiento activo y grado de participación social en el Estado de México. Metodología. Investigación cuantitativa, descriptiva y transversal, con un muestreo no probabilístico por conveniencia de 50 personas mayores, habitantes de los municipios de Toluca que firmaron previo consentimiento informado. Instrumento. Encuesta de elaboración propia, con base en la Encuesta sobre envejecimiento demográfico en el Estado de México (ESEDEM, 2008), validad por expertos y confiable al 95% para capturar aspectos sociales relevantes de la vejez. Resultados. La mayoría de personas mayores son casadas, no participa en actividades económicas, no cuentan con seguridad social, presentan morbilidades, realizan actividades básicas de la vida diaria pero no tienen asistencia o apoyo familiar. Conclusiones. Las limitaciones sociales de las personas mayores que influyen en la búsqueda de un envejecimiento activo son y grado de participación social en el Estado de México son; la nula participación en actividades económicas, la negativa autopercepción de sentirse desvalorados para poder desempeñarse en algún puesto de trabajo, poca seguridad social y prevalencia de enfermedades.
Frequencies of Warm Debris Disks Based on Point Source Catalogs of Spitzer, WISE, and Gaia
Authors: Mizuki Toshiyuki , Momose Munetake , Aizawa Masataka , Kobayashi Hiroshi 
Published: May 2024

Abstract
More than a thousand warm debris disks have been detected as infrared excess at mid-infrared wavelengths, and their frequencies have been obtained for various spectral types of stars. However, the dependence of the frequencies on spectral type is still debated because the number of stars with significant and detectable infrared excess is limited. Herein, we present the largest systematic search for infrared excess using data from Gaia, WISE, and Spitzer. We identified 373, 485, and 255-reliable infrared excesses in the mid-infrared archival data at wavelengths of 12, 22, and 24 μm for WISE/W3, W4, and Spitzer/MIPS ch1, respectively. Although we confirmed that more massive stars tend to show higher frequencies of debris disks, these disk frequencies are relatively flat for both low- and intermediate-mass stars, with a jump at 7000 K for all three wavelengths. Assuming that bright, warm debris disks have lifetimes of a few to several hundred million years, the disk frequency can be understood as the ratio between the timescale and the upper limits of the sample ages. We also found that intermediate-mass stars with infrared excess tend to be bluer and fainter along the evolutionary track than those without, implying that massive stars hosting debris disks are relatively young, with an isochronal age of approximately 500 Myr. These tendencies are reasonably explained by a standard scenario in which debris disks are likely to be produced by collisions of planetesimals in the early stages of stellar evolution, such as the Late Heavy Bombardment.