bluuebunny/crossref_metadata_2025_split huggingface dataset:
Myo-inositol Levels in the Dorsal Anterior Cingulate Cortex Predicts Anxiety-to-Eat in Anorexia Nervosa
Authors: Song Yulu , Guo Sarah H. , Davies-Jenkins Christopher W. , Guarda Angela , Edden Richard A.E. , Smith Kimberly R. 
Published: May 2024

AbstractBackgroundAnorexia nervosa (AN) is a mental and behavioral health condition characterized by an intense fear of weight or fat gain, severe restriction of food intake resulting in low body weight, and distorted self-perception of body shape or weight. While substantial research has focused on general anxiety in AN, less is known about eating-related anxiety and its underlying neural mechanisms. Therefore, we sought to characterize anxiety-to-eat in AN and examine the neurometabolic profile within the dorsal anterior cingulate cortex (dACC), a brain region putatively involved in magnifying the threat response.MethodsWomen seeking inpatient treatment for AN and women of healthy weight without a lifetime history of an eating disorder (healthy controls; HC) completed a computer-based behavioral task assessing anxiety-to-eat in response to images of higher (HED) and lower (LED) energy density foods. Participants also underwent magnetic resonance spectroscopy of the dACC in a 3 Tesla scanner.ResultsThe AN group reported greater anxiety to eat HED and LED foods relative to the HC group. Both groups reported greater anxiety to eat HED foods relative to LED foods. The neurometabolite myo-inositol (mI) was lower in the dACC in AN relative to HC, and mI levels negatively predicted anxiety to eat HED but not LED foods in the AN group only. mI levels in the dACC were independent of body weight, body mass, and general anxiety.ConclusionsThese findings provide critical new insight into the clinically challenging feature and underlying neural mechanisms of eating-related anxiety and indicate mI levels in the dACC could serve as a novel biomarker of illness severity that is independent of body weight to identify individuals vulnerable to disordered eating or eating pathology as well as a potential therapeutic target.
Loss of SPNS1, a lysosomal transporter, in the nervous system causes dysmyelination and white matter dysplasia
Authors: Ichimura Yoshinobu , Sugiura Yuki , Katsuragi Yoshinori , Sou Yu-Shin , Uemura Takefumi , Tamura Naoki , Komatsu-Hirota Satoko , Ueno Takashi , Koike Masato , Waguri Satoshi , Komatsu Masaaki 
Published: May 2024

AbstractProtein spinster homolog 1 (SPNS1) is a lysosomal transporter of lysophospholipids and sphingosine, which has recently been identified to be mutated in patients with neurodegeneration. However, its physiological role, especially in the nervous system, remains largely unknown. In this study, we generated, for the first time, nervous system-specificSpns1knockout mice,Spns1flox/flox;nestin-Cre, and found that the mutant mice develop neurological symptoms, such as epilepsy, and growth retardation, and die by 5 weeks of age. The mutant mice exhibited dysmyelination and oligodendrocyte shedding, while maintaining the neurons. Mutant mouse brains showed accumulation of lysophospholipids, predominantly in regions, such as the olfactory bulb and hippocampus. Furthermore, whereas sphingosine accumulated in the mutant mouse brain, the levels of ceramide and sphingoglycolipids, which are the main myelin components, were decreased. Our findings imply that abnormal sphingosine metabolism causes dysmyelination and white matter dysplasia in brain-specificSpns1-knockout mice, and indicate a possible role of SPNS1 mutation in the pathogenesis of congenital cerebral white matter dysplasia in humans.
Biosensor imaging of G protein mediated Signaling Pathways Activated Immediately Downstream of CaSR
Authors: Chavez-Abiega Sergei , Bruggeman Frank J. , Goedhart J. 
Published: May 2024

ABSTRACTGenetically encoded biosensors allow us to study events in single cells in real time. Here, we used biosensors with a read-out based on Förster resonance energy transfer (FRET) or intensity to investigate the main signaling pathways activated immediately downstream of the calcium sensing receptor (CaSR) in HEK-293 cells. CaSR responds to its endogenous ligand, calcium, to activate Gq and Gi protein dependent pathways. We demonstrate that CaSR activates Gq to promote intracellular calcium mobilization, and we monitored these two events simultaneously in the same cells. We also observed that CaSR activates the 3 Gαi subtypes and decreases cAMP levels in a Gi-dependent manner. Moreover, the use of negative allosteric modulator NPS-2143 can inhibit these signaling events and also rapidly disrupts them if added after receptor activation by calcium stimulation. In addition, the increases in calcium and cAMP levels were respectively enhanced when activation of Gi or Gq proteins was prevented. Finally, we provide evidence that CaSR does not couple to G13 proteins, and that activation of RhoA by CaSR is solely dependent on Gq/G11 activity.
Exploring community satisfaction, identification and reciprocity norm for customer value co-creation: insights from virtual brand communities
Authors: Liu Yurong , Lu Xinxin , Xiong Zhengde , Wang Bo , Yao Zhu , Luo Lingna 
Published: May 2024

PurposeUser value co-creation behaviors are crucial for the sustainable development of Virtual Brand Communities. This research, grounded in social exchange theory, investigates the impact of community satisfaction and identification on customer value co-creation behaviors and further explores how the reciprocity norm moderates these relationships.Design/methodology/approachOur research data were collected from users across multiple brand communities, totaling 481 survey responses. Structural equation modeling was performed to test the research hypotheses.FindingsThese results provide in-depth insights into the nexus between user-community relationships and customer value co-creation behaviors. While community satisfaction and identification positively influence co-creation, their effects vary across different value co-creation behaviors. Notably, the reciprocity norm within the community dampens the relationship between community satisfaction and value co-creation behaviors.Originality/valueUnlike previous studies focusing on customer value co-creation behaviors, our research emphasizes social exchange, unveiling the mechanisms behind customer value co-creation. Our findings not only enrich the body of knowledge on customer value co-creation but also deepen our understanding of online collective behavior and knowledge sharing, offering valuable insights for the development of virtual communities.
Design and optimization of a domestic solar dryer: an analytical approach
Authors: Shimpy Shimpy , Kumar Mahesh , Kumar Anil 
Published: May 2024

PurposeFood loss and wastage is an issue of global concern and the household sector is one of the biggest contributors to this. Solar drying has been explored by many eminent researchers as a solution to this problem but there have been concerns about the lack in designs, higher cost, lower performance, and consumer acceptability. The present research aims to design a small-scale domestic solar dryer by using computer software.Design/methodology/approachResponse surface methodology (RSM) and computational fluid dynamics (CFD) are used to design the domestic solar dryer. Initially, design variables (inlet and outlet vent height) are identified and a design of experiments has been created using RSM for set of experimental runs. The experimental runs suggested by RSM were carried out using CFD simulation in COMSOL Multiphysics software and the results were used for optimization of response variables (outlet velocity and drying chamber temperature) in RSM.FindingsOutlet vent height was found to be most significantly affecting parameter to both the responses. The optimum values of inlet and outlet vent heights were 0.5 and 2.5 cm, respectively with the overall desirability of 0.728. The model accuracy was tested by conducting a confirmation test as post processing in design expert software.Originality/valueDesigning a solar dryer is a complex, costly and time consuming process, this study presents an easy, economic and fast method to design a new solar dryer. It would help researchers to design and develop new domestic as well as large size industrial solar dryer.
Cultivating workplace fairness: the ripple effect of organizational justice on work withdrawal, incivility as the mediator
Authors: Gupta Supriya , Sharma Ranjana , Gupta Aditi 
Published: May 2024

Purpose
The purpose of this study is to examine the influence of employees' perceptions of organizational justice on workplace incivility and work withdrawal behaviours within the hotel industry. Additionally, the study aims to explore the mediating role of incivility in the relationship between organizational justice and work withdrawal behaviour.

Design/methodology/approach
Data for this study were collected from 213 employees in the hotel industry using a structured questionnaire. The collected data were then analysed using structural equation modelling (SEM) technique, allowing for a comprehensive examination of the relationships between organizational justice, incivility and work withdrawal behaviour.

Findings
The study reveals that perceptions of organizational justice directly impact workplace incivility and indirectly affect work withdrawal behaviour. Specifically, low perceptions of organizational justice are associated with increased incidences of uncivil behaviour among employees, which, in turn, have detrimental effects on their work withdrawal behaviours.

Originality/value
This study contributes to the existing literature by shedding light on the intricate relationships between organizational justice, workplace incivility and work withdrawal behaviour within the hotel industry context. Moreover, it highlights the importance of addressing both organizational justice perceptions and incivility to foster positive employee outcomes and organizational well-being, particularly in environments characterized by changing contextual conditions.
Influence of ionic liquid/liquid metals on the lubrication properties of lithium grease
Authors: Wen Maosheng , Hu En Zhu , Fei Xingpeng , Hu Kunhong 
Published: May 2024

Purpose
This paper aims to use an ionic liquid (IL, [HMIM]PF6) to improve the lubrication performance of liquid metal (LM) as a lithium grease additive and to expand the application range of LM.

Design/methodology/approach
In this paper, the different mass ratios of [HMIM]PF6/LM mixtures were added into the lithium grease on a four-ball tribo-meter to investigate the effects of its tribological behavior. Scanning electron mircoscope/energy dispersive spectroscopy and X-ray photoelectron spectroscopy were used to reveal the anti-wear and friction-reducing mechanism of the additives.

Findings
When the load was used at 461 N, the average coefficient of friction (ACOF) and average wear scar diameter (AWSD) of steel ball Lubricated with grease with an optimal ratio of 2:3 ([HMIM]PF6/LM) were reduced by 32.8% and 30.5%, respectively. Friction and wear mechanisms are ascribed to friction-induced additive components that can simultaneously form a composite lubrication film consisting of FePO4, FeF3, Ga2O3, In2O3 and SnO2.

Research limitations/implications
Compared with the pure lithium-based grease, when [HMIM]PF6/LM was added with an optimal ratio of 2:3, the ACOF and AWSD were reduced by 12.4% from 0.097 to 0.085 and 23.8% from 552.117 µm to 420.590 µm under 392 N, respectively. When at 461 N, the ACOF and AWSD of steel ball were reduced by 32.8% from 0.122 to 0.082 and 30.5% from 715.714 µm to 497.472 µm, respectively. It was shown that the simultaneous addition of LM and [HMIM]PF6 can form a composite lubrication film consisting of FePO4, FeF3, Ga2O3, In2O3 and SnO2.

Originality/value
In this paper, [HMIM]P F6 is added with LM simultaneously to improve the lubrication properties of lithium grease, and expand the application scope of LM.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-01-2024-0017/
The role of food-related consideration of future consequences, health and environmental concerns in explaining sustainable food (fish) attitudes
Authors: Tuu Ho Huy , Khoi Nguyen Huu 
Published: May 2024

PurposeThis study explores the direct and indirect effects of two components of food-related consideration of future consequences (CFCs), including CFC-Immediate and CFC-Future, on sustainable food attitudes (SFA) via food-related health and environmental concerns.Design/methodology/approachPartial least squares structural equation modeling technique was used on a data set of 664 Vietnamese consumers collected in Central Vietnam to evaluate measurement and structural models.FindingsCFC-Immediate and CFC-Future as well as health and environmental concerns have positive effects on SFA. Indirect effects of CFC-Immediate on SFA via health concerns and CFC-Future on SFA via health/environmental concerns are also discovered.Research limitations/implicationsFuture studies should examine the impact of environmental values on CFCs, forming a more comprehensive understanding regarding the relationship between the two variables, especially by including a wider range of sustainable food types to gain diverse knowledge about sustainable food consumption.Practical implicationsCommunicative messages should focus on both health and environmental concerns while emphasizing both immediate and more distant outcomes of sustainable food (fish) consumption for individuals with different dominant temporal orientations.Originality/valueThis study sheds light on the direct and hierarchical relationships among food-related CFCs, health and environmental concerns and SFA to better understand the intricate psychological process of sustainable food consumption.
Exploring the impact of gamified elements on college students' learning in virtual learning communities
Authors: Yang Yongzhong , Yu Aixian , Li JinJing , Shafi Mohsin , Fauzi Muhammad Ashraf 
Published: May 2024

PurposeGamification has emerged as a dynamic force in education, with increasing interest in its impact on college students' learning. Most previous research regards gamification as a single element and only focuses on the cognitive level of gamification elements, lacking an overall exploration of the impact mechanism of gamification elements. Against the backdrop of virtual learning communities, we apply the cognition-affection-conation theory to examine the influence of various gamification elements on college students' online learning behaviors, examining both cognitive and affective pathways.Design/methodology/approachData were collected through a predefined questionnaire from 11 Chinese virtual learning communities, with 587 respondents participating in the study. SmartPLS was employed to conduct a Partial Least Squares (PLS) analysis of the research model and test the hypotheses.FindingsOur findings reveal that immersion and achievement-oriented gamification elements positively impact learning behavior. Conversely, the social gamification element exhibits a negative influence due to social burnout within virtual learning communities. This study pioneers a model to understand the intricate influence mechanisms of gamification elements on college students' online learning behaviors. The model contributes to the enriched exploration and practical application of college students' learning behaviors in virtual learning communities.Originality/valueUnlike previous studies that often treat gamification as a single element and focus solely on cognitive aspects, this research explores both cognitive and affective pathways using cognition-affection-conation theory. By examining the influence of various gamification elements on college students' online learning behaviors in virtual learning communities, this study provides nuanced insights. In particular, immersion and achievement-oriented gamification elements positively impact learning behavior, while social gamification elements have a negative influence due to social burnout. This comprehensive approach deepens our understanding of how gamification affects students' learning experiences, enriches knowledge, and provides practical insights for educators and instructional designers.
Redefining resilience: insights into project management’s capabilities of organisations through the pandemic and beyond
Authors: Malik Sheraz Alam , Bustami Rami 
Published: May 2024

PurposeTo better understand the resilience of project management (PM) companies post-pandemic and gain insights into the interplay of the level of preparation, the status of the project and the size of the company.Design/methodology/approachLogistic regression was used to analyse the data from 285 companies belonging to more than 7 sectors to understand the crucial factors required to have above-standard project performance post-pandemic.FindingsHigher project performance was observed in companies with more than 30 years of experience, whereas company history, target group or PM activity did not predict better project performance. The retail sector is leading across all the sectors, whereas the majority of companies have still not recovered from the pandemic.Research limitations/implicationsNew factors like planning and controlling phases in PM are identified in Gulf Cooperation Council (GCC) settings to be most impacted post-pandemic, whereas size and length of being in business are other key variables highlighted in this research for better PM performance post-pandemic.Originality/valueA large-scale analysis of 285 Saudi companies is quite novel in scale and innovation. This cross-sector empirical research highlights key areas of consideration post-pandemic, which were missing from the narrative due to access and emerging issues earlier.
Deviant unicorns: monocerate and dicerate versions of Carlotta Roewer, 1943 (Opiliones: Gonyleptidae), with description of four new species from Eastern Brazil
Authors: Kury Adriano Brilhante , Mendes Amanda Cruz 
Published: May 2024

AbstractIn this study, the understanding of the harvestman genus Carlotta Roewer, 1943, is expanded. Carlotta currently comprises two species found in central Espírito Santo state. The descriptions of the existing Carlotta species have been supplemented, including genital morphology. Four new species are herein described—Carlotta beckeri sp. nov., Carlotta bicornis sp. nov., Carlotta iohannis sp. nov. and Carlotta obtortrix sp. nov.—extending the range of the genus both southwards and northwards from southern Espírito Santo to southern Bahia. Among the new findings, a unique trait is exhibited by two species: a pair of spines on the ocularium (dicerate), in contrast to a single spine (monocerate). This variation is significant, as the number of spines on the ocularium plays a crucial role in the Roewerian diagnosis for the genus. The characterisation of the genital morphology of Carlotta species is refined, with the identification and naming of two distinctive structures: the dilophium—two parallel lamellate ridges along the disto‐ventral surface of the stylus, terminating in a broader loop—and the skeletal flabellum—a framework of arched cylindrical tapering branches with multiple ramifications. By shedding light on these newly identified structures, a more comprehensive understanding of the diversity and evolutionary traits within the Gonyleptidae is contributed through this study.
Continuing professional development training needs of allied health professionals in regional and rural Victoria
Authors: Pang Michael , Sayner Alesha , McKenzie Kylie 
Published: May 2024

AbstractObjectiveThe aim of the study was to identify continuing professional development (CPD) needs of allied health professionals (AHP) in regional and rural Victoria.DesignThis study was an online cross‐sectional design conducted between December 2022 and February 2023.Settings and ParticipantsAHPs employed at a large multi‐site regional public health service providing acute, subacute, community and outpatient care in Victoria, Australia.Main Outcome Measure(s)The online questionnaire included four sections investigating satisfaction of CPD, prioritised topics for CPD, preference for CPD sourcing and perceived capabilities in delivering education. To investigate prioritised topics of CPD, a tool was adapted from the Hennessy Hicks Training Needs Analysis questionnaire to align with allied health (AH) career pathways. For organisational alignment, a second questionnaire was sent to AH managers.ResultsThe response rate was 17% (53/316 AHPs) from members of 10 AH professions. The median years of clinical experience for participants was between 2 and 5 years. Participants with 6–10 years of clinical experience reported the lowest level of satisfaction. Research and education were identified as areas of highest training need. Self‐perceived competence in education delivery was proportionately lower in areas of assessment, developing digital learning and constructive alignment.ConclusionCPD needs for AHPs in a regional and rural health service were shown to vary by career stage and weighted towards developing research and education delivery capabilities. Findings from this study may support public health sector and policy investment in CPD opportunities to support horizontal career progression opportunities, a balance of internal and externally sourced professional development and strategic investment in education delivery capabilities.
Identifying the top 10 priorities of adolescents with a physical disability regarding participation in physical activity: A Delphi study
Authors: Brady Karen , Cleary Ronan , O'Gorman Eva , McDonough Suzanne , Kerr Claire , Kiernan Damien , McConkey Elaine , Ryan Jennifer , Malone Ailish 
Published: May 2024

AbstractAimTo establish consensus among adolescents with a physical disability regarding their priorities for enhancing participation in physical activity and help inform the design of future interventions for participation in physical activity.MethodWe conducted a national multi‐round Delphi study involving adolescents with a physical disability aged 13 to 17 years. Round 1 of the initial survey consisted of open‐ended questions. Free‐text responses were then analysed thematically, creating items categorized according to the family of participation‐related constructs (fPRC). In round 2, participants rated the perceived importance of these items using a 5‐point Likert scale. The top 10 priorities were constructed from the highest‐ranked items.ResultsOne hundred and sixteen participants (mean age = 14 years 7 months, range = 13–17 years; 66 males; 58 with cerebral palsy; 43 wheelchair users) completed round 1; 108 items were included in round 2. Fifty‐eight items were rated as either ‘important’ or ‘really important’ by 70% of participants. The top 10 priorities were rated as important or really important by 82% to 94% of participants with a mean Likert score of 4.40 (range = 4.25–4.63). Seven of the top 10 priorities were related to the environmental context of the fPRC. The other three were related to involvement and the related concept of preference.InterpretationThe priorities identified will help inform future physical activity interventions for adolescents with a physical disability.