bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aecubea Regina Cypri ex voto Assisium venit: The Myth of a Queen of Cyprus in Assisi
Authors: Andronikou Anthi 
Published: May 2024

Abstract
Among the legends disseminated by the friars of San Francesco in Assisi was an enduring tale that surfaced at the dawn of the sixteenth century, according to which a thirteenth-century queen of Cyprus was buried inside an exuberant Gothic canopied tomb in the convent’s Lower Church. This study examines the queen’s supposed funerary monument, explores the varying permutations of the legend, reveals the presumed gifts she donated to the friars, and unravels the conundrum surrounding her identity and the position of her tomb. In considering the convent-specific and wider contexts of Italy and Cyprus, the paper deconstructs the myth by uncovering new archival sources and offers fresh insights into the identity and activity of the Cypriot queen in Assisi. More importantly, it argues that the legend distorted historical facts as a means to enhance the connection between the Franciscan Order, the convent, and the Holy Land.
Job Creation and Job Destruction in Indian Manufacturing
Authors: Goswami Diti , Paul Sourabh B. 
Published: May 2024

The reallocation of jobs is crucial in determining the movement of workers, the unemployment rate, the wage dynamics, the life cycle of firms and industries and the aggregate productivity growth. This article analyses job reallocation in terms of simultaneous establishment-level job creation and job destruction in Indian organised manufacturing. The study employs longitudinal data from the Annual Survey of Industries (ASI) from 2004–2005 to 2014–2015 and the methodology stated in Davis and Haltiwanger (1992) to analyse job reallocation. During the expansionary periods, job creation and job destruction were rising, while during the contractionary period from 2008 to 2009 onwards, job creation declined, whereas job destruction was constant. The reallocations of jobs varied substantially across the narrow heterogeneous sectors defined by observable plant characteristics. The rate of these simultaneous job creation and destruction processes is high for many establishments and accounts for a significant portion of worker reallocation. However, the consistency of these newly created and destroyed jobs is low. Theories like ‘passive learning’ and ‘between-sector employment shifts’ partially explain this phenomenon of high job reallocation. The study provides useful policy insights to improve manufacturing employment during the process of frequent job creation and destruction, especially in a developing economy. JEL Codes: J01, J23, J21, J40, F63
Factors influencing access to psychiatric care among persons with psychosis living in a rural community in south India
Authors: Reddy Shanivaram K , Thirthalli Jagadisha , Naveen Kumar Channaveerachari , Manjunatha Narayana , Rawat Vikram Singh , Gangadhar Bengalore Nanjundayya 
Published: May 2024

Background: A substantial proportion of persons with psychosis (PWP) remain untreated in the community across the world. Factors that preclude them from accessing psychiatric treatment are poorly studied. In this study, we explored the factors that prevented persons with schizophrenia and their caregivers from accessing psychiatric treatment using an interview schedule specifically developed for this purpose. Methods: We identified individuals with schizophrenia and related disorders who had never accessed psychiatric treatment. We interviewed 67 such individuals and their family members using a validated tool, the Schedule of Factors Influencing Access to Treatment (SOFIAc) and analysed the data using descriptive statistics. Results: The M ( SD) number of factors reported to preclude individuals with psychosis and families from seeking psychiatric treatment was 10 (3.32). No PWP/family reported any single factor as the sole reason for not accessing treatment. Distance to the nearest psychiatric centre (97%), PWP’s/family members’ knowledge and attitude towards symptoms of psychosis and treatment (92.5%), financial problems (91%), lack of insight and active resistance to efforts towards treatment (86.6%), lack of support from the family (83.6%) and family issues and dynamics (79.1%) were reported to be the commonest factors that precluded them from accessing psychiatric treatment. Conclusions: The reason for individuals with psychosis and their family members not accessing psychiatric treatment was invariably multifactorial, involving, on average, 10 factors. Programmes that target the reduction of the treatment gap should be cognizant of the multifactorial nature of the challenge of reaching psychiatric treatment for persons with psychoses.
“Dual Pandemics”: Intersecting Influences of Anti-Black Racism and the COVID-19 Pandemic on the Mental Health of Black Youth
Authors: Osman Samah , Aiello Olivia , Brouillette Khadija , Taylor Mischa , McKenzie Kwame , Renzaho Andre M. N. , Henderson Jo , Hamilton Hayley , Salami Bukola 
Published: May 2024

Background The intersection of the COVID-19 pandemic with systemic anti-Black racism in the form of police violence and the subsequent Black Lives Matter movement has created an especially critical juncture to examine the mental health of Black youth. Purpose The purpose of this study was to understand the intersecting impacts of anti-Black racism and the COVID-19 pandemic on the mental health of Black youth. Methods A youth-engaged research approach and intersectionality framework were utilized. Semi-structured interviews with Black youth across Canada (ages 16 to 30, n  = 48) were conducted online via Zoom and analyzed using thematic analysis. Fourteen Black youth were hired to form a Black youth advisory committee, who guided the research process. Results The “dual pandemics” of the COVID-19 pandemic alongside highly publicized incidents of racism and the subsequent Black Lives Matter movement negatively impacted participants’ mental health. Four main themes emerged: (1) ongoing exposure to acts of anti-Black racism (2) compounding effect of racism on mental health; (3) high stress levels and fear; and (4) anger and emotional fatigue from lack of shared, long-term solutions. Conclusion The simultaneous occurrence of the COVID-19 pandemic and instances of systemic anti-Black racism in the form of police violence presented “dual pandemics” for the Black community, profoundly impacting the mental health of Black youth and adding urgency and impetus to its prioritization. Results of this study indicate that it is critical to explore each event individually as well as the combined impact on the mental health of Black youth, particularly from a racial perspective.
Addressing Culturally Based Hidden Bias and RacisM (A-CHARM) Using Simulation Experiences, Nik’s Story: A Quasi-Experimental Study
Authors: Sawhney Monakshi , Li Jenny S. , Patterson Michaela , Gumapac Nathaniel P. , Sau Crystal , Akbari Ali 
Published: May 2024

Background/Purpose Racism and hidden bias experienced by underrepresented nursing students contribute to a loss of confidence and anxiety. The A-CHARM nursing project developed virtual simulation experiences for nursing students to practice how to address racism. ‘Nik's Story’ virtual simulation was created as part of the A-CHARM project. The purpose of this study was to examine the effectiveness of an education intervention, that included Nik's story, on cultural humility and cultural diversity awareness. Method This quasi-experimental study included a convenience sample of final year nursing students. After informed consent, participants completed a pre-intervention questionnaire that included the Cultural Humility Scale “context for difference in perspective” subscale, and the Cultural Diversity Awareness questionnaire to assess baseline knowledge. Students participated in an education intervention that included a lecture, Nik's story virtual simulation experience, a debrief and then completed a post-education/simulation questionnaire that included usability/learner engagement questions and the Cultural Humility Scale “context for difference in perspective” subscale, and the Cultural Diversity Awareness questionnaire. Results Forty-seven students consented and completed the pre/post intervention questionnaire. Participants rated the effectiveness, engagement and usability of the simulation experience highly. There was a significant positive change in cultural humility “context for difference in perspective” subscale (pre-scores = 6.9, SD = 3.3; post-scores = 31.0, SD = 3.8, p < 0.001), and cultural diversity awareness (pre-scores = 95.4, SD = 8.9; post-scores = 103.4, SD = 9.8, p < 0.001). Discussion This intervention was effective in improving cultural humility and cultural diversity awareness in nursing students. Conclusion Simulation experiences regarding racism in the clinical setting provide a strategy for students to learn how to professionally navigate unwanted experiences.
Peripapillary pachychoroid syndrome treated with dexamethasone implant: A case report
Authors: Feo Alessandro , La Spina Carlo , Romano Mario R , Querques Giuseppe , Panico Edoardo , Panico Claudio , Del Turco Claudia 
Published: May 2024

Purpose To describe a case of peripapillary pachychoroid syndrome (PPS) in a diabetic patient with cystoid macular edema (CME), treated with intravitreal dexamethasone implant (IDI) injection. This report also illustrates the history of the disease after repeated IDI and dexamethasone topical treatment. Methods A case report. Results A 77-year old male patient with PPS and good diabetic control was treated with dexamethasone implant for CME. After an initial morphofunctional improvement associated with a first IDI, the disease relapsed after the second dexamethasone implant injection. This was associated with a significant increase in both intraretinal fluid and choroidal thickness, with subsequent visual acuity (VA) decrease. At this point, a topical dexamethasone treatment was performed and, despite a morphological improvement, VA worsened compared with baseline, likely because of anatomical damage. Conclusion In this report, the importance of the recognition of PPS is underlined and the possible occurrence of a “rebound” effect due to repeated IDI is described.
The Characteristics of White Dot Syndromes Following SARS-COV-2 Infection: A Systematic Review
Authors: Serhan Hashem Abu , Suilik Husam Abu , Hassan Amr K. , AlSamhori Jehad Feras , Hassan Abdul Rhman , Siddiq Abdelmonem , Helal Rehab Sabry , Metilda Sudha , Elnahry Ayman G 
Published: May 2024

Purpose To review all studies reporting the occurrence of white dot syndromes (WDSs) following SARS-COV-2 infection. Methods On May 12, 2023, we registered our protocol on PROSPERO [registration number: CRD42023426012]. Five different databases including PubMed, Scopus, Web of Science, Google Scholar, and Science Direct were searched up to May 2023. We included all studies that reported the symptoms of WDSs following SARS-COV-2 infection. The data was extracted using a uniform Excel extraction sheet. All statistical tests were conducted with a 95% confidence interval and a 5% error margin. A p-value of less than 0.05 was considered statistically significant. The publication bias of included studies was assessed using JBI Critical Appraisal Checklist for Case Reports and IHE Quality Appraisal Checklist for Case Series studies. Results This review included thirty-two studies involving forty-eight patients. Acute macular neuroretinopathy was the most common disease (70.8%) followed by multiple evanescent white dot syndrome (14.6%) with 58.3% of WDS after their first SARS-COV-2 infection, and paracentral acute middle maculopathy (4.1%). They were mostly unilateral (56.2%). The presenting symptoms were blurred vision (70.8%), visual field disturbance (68.7%), and photopsia (20.8%). About 35.4% of the patients improved by their treatment and future complications were persistent scotoma (4.2%) and macular edema (2.1%). Conclusion White dot syndromes are very rare entities. Our findings suggest a possible association between white dot syndrome onset and SARS-COV-2 infection. We recommend ophthalmologists should be aware of this suggested association to deliver better management and patients’ care.
Telemedicine: Does it have a place in surgical oncology practice?
Authors: Kelley Jesse K , Kelly Kathrine A , Rechner Sydney , Brown Hannah , Kim Sarah , Spencer Sophia , Martin Elizabeth , Reed Charles , Wright Gerald P , Assifi Murwarid M , Chung Mathew 
Published: May 2024

Background Telemedicine has gained traction in surgical subspecialties, particularly since the COVID-19 pandemic. This study aims to identify whether telemedicine can be appropriately integrated within surgical oncology practice. Methods This retrospective study evaluated patients who received either telemedicine or office follow-up after undergoing surgical oncology operations between 2016 and 2021. The telemedicine group (TG) and office group (OG) received a 15-question survey regarding their satisfaction with their care. Patient outcomes and responses were analyzed utilizing propensity-score matching in 1:1 fashion. Results Telemedicine group and OG each had 21 patients. Length of stay, complication frequency, follow-up frequency, and readmissions frequency within 90-days were comparable between groups. Telemedicine group expressed comparable satisfaction with postoperative care relative to OG (95.2% vs. 85.7%, p = 0.61). All telemedicine patients said they would utilize telemedicine again in the future and would recommend its use to others. Conclusion Patient satisfaction with postoperative telemedicine follow-up is comparable to those with in-person follow-up.
Small Nucleolar RNAs as Diagnostic and Prognostic Biomarkers in Cancer: A Systematic Review and Meta-Analysis
Authors: Gao Liyun , Fan Junfei , He Jiayin , Che Xiangxin , Wang Xin , Han Chunhua 
Published: May 2024

Objectives Small nucleolar RNAs (snoRNAs) form clusters within the genome, representing a mysterious category of small non-coding RNAs. Research has demonstrated that aberrant snoRNAs can contribute to the development of various types of cancers. Recent studies have identified snoRNAs as potentially valuable biomarkers for the diagnosis or/and prognosis of cancers. However, there has been a lack of comprehensive reviews on prognostic and diagnostic snoRNAs across different types of cancers. Methods We conducted a systematic search of various databases including Google Scholar, Medline, Cochrane, Scopus, PubMed, Embase, ScienceDirect, Ovid-Medline, Chinese National Knowledge Infrastructure, WanFang, and SinoMed with a time frame reception to December 30, 2022. A total of 49 relevant articles were included in our analysis, consisting of 21 articles focusing on diagnostic aspects and 41 articles focusing on prognostic aspects. Pooled odds ratio, 95% confidence intervals (CIs), and hazard ratio (HR) were utilized to evaluate clinical parameters and overall survival (OS), respectively. Result The findings indicated that area under the curve, sensitivity, and specificity were 0.85, 75%, and 80% in cancer, respectively. There was a possibility that snoRNAs had a positive impact on the diagnosis (risk ratio, RR = 2.95, 95% CI: 2.75-3.16, P = 0.000) and OS (HR = 1) in cancer. Additionally, abnormally expressed snoRNAs were associated with a positive impact on OS time for chronic lymphocytic leukemia (HR: 0.88, 95%Cl: 0.69-1.11, P < 0.00001), colon adenocarcinoma (HR: 0.97, 95%Cl: 0.91-1.03, P < 0.0001), and ovarian cancer (HR: 0.98, 95%Cl: 0.98-0.99, P < 0.00001). However, dysregulated snoRNAs of colon cancer and colorectal cancer had a negative impact on OS time (HR = 3.01 and 1.01 respectively, P < 0.0001). Conclusion The results strongly suggested that snoRNAs could serve as potential novel indicators for prognosis and diagnosis in cancers. This systematic review followed the guidelines of the Transparent Reporting of Systematic Review and Meta-Analyses (PROSPERO register: CRD42020209096).
Lifestyle Intervention Improves Parasympathetic Activity in Hypertrophic Cardiomyopathy
Authors: Alyahya Alaa I. , Charman Sarah J. , Okwose Nduka C. , Fuller Amy S. , Eggett Christopher , Luke Peter , Bailey Kristian , MacGowan Guy A. , Jakovljevic Djordje G. 
Published: May 2024

Background A limited number of studies have investigated the effects of lifestyle interventions in hypertrophic cardiomyopathy (HCM). This study evaluated the effect of a novel lifestyle intervention incorporating physical activity (PA) and dietary nitrate supplementation on heart rate variability (HRV) and haemodynamic measures in HCM. Methods Twenty-eight individuals with HCM were randomised into either the intervention or control group. Frequency-domain HRV measures including low frequency power (LF), high frequency power (HF) and LF/HF were recorded at rest using bioimpedance. Non-invasive haemodynamic variables were recorded at rest using bioreactance. Participants in the intervention group consumed 6 mmol of nitrate daily (concentrated beetroot juice) and were instructed to increase and maintain daily PA by ≥ 2000 steps/day above baseline for 16 weeks. Control group participants retained their usual lifestyle and monitored daily step counts. Results There was a significant increase in post-intervention HF power (7.54 ± 2.14 vs 8.78 ± 1.60 ms2, P < .01) and LF power (6.89 ± 2.33 vs 8.17 ± 1.55, P < .01) in the intervention but not in the control group. Resting mean arterial blood pressure (MABP) in the intervention group significantly reduced at follow-up (108 ± 6 vs 102 ± 7 mmHg, P < .01). Conclusions A novel lifestyle intervention including PA and dietary nitrate supplementation enhanced parasympathetic activity and resting MABP in HCM.
Experimental comparison of first-pass effect between direct thromboaspiration and combined thrombectomy in the setting of distal basilar occlusion
Authors: Seiffert Reza , Brina Olivier , Reymond Philippe , Hofmeister Jeremy , Bernava Gianmarco , Rosi Andrea , Michels Lars , Kulcsar Zsolt , Lovblad Karl-Olof , Machi Paolo 
Published: May 2024

Background Studies investigating endovascular therapy in vertebro-basilar stroke have led to controversial results in the past, but recent randomized trials seem to show an effectiveness superiority of endovascular therapy versus best medical treatment. However, uncertainty remains concerning many aspects of thrombectomy in acute basilar artery occlusion, notably technical considerations. This study compared the first-pass effect of direct thromboaspiration and combined thrombectomy in the setting of distal basilar occlusion. Methods An in-vitro experimental set-up was used, consisting of a vascular phantom model and thrombus analogs of different consistencies to mimic human clots. Thrombus analogs were injected into the model through the vertebral artery and flowed to the basilar distal third to mimic a distal basilar occlusion. Ten procedures were performed for each thrombus analog stiffness and technique (direct thromboaspiration versus combined thrombectomy). Results Direct thromboaspiration showed an overall first-pass effect rate of 83.3% (25/30) and was particularly effective for ultra-soft and soft clot analogs, but decreased for hard clot analogs. Combined thrombectomy had an overall first-pass effect rate of 56.7% (17/30). The effect rate for ultra-soft and soft clot analogs was 60% and 50% for hard clot analogs. In the softer clot analogs, the stent-retriever device used for the combined thrombectomies tended to deviate the clot analog from a co-axial trajectory with the aspiration catheter. Conclusions In the context of distal basilar occlusion, our in-vitro results showed that higher first-pass effect rates were achieved with direct thromboaspiration compared to combined thrombectomy in all types of thrombus analogs.
Quantification of steal flow on Doppler ultrasound in patients with arteriovenous graft for hemodialysis
Authors: Kang Kyoungin , Lee Jung Ho , Hwang Hong Pil , Kaliannagounder Vignesh Krishnamoorthi , Park Chan Hee , Kwak Hyo Sung 
Published: May 2024

Purpose Arteriovenous fistula (AVF) is the preferred treatment for long-term hemodialysis patients to allow reliable vascular access. Arteriovenous graft (AVG) is monitored using Doppler sonography to check a vessel’s condition and predict complications such as steal syndrome. In this study, we developed an analysis algorithm and method to quantify steal syndrome using Doppler sonography. Methods Doppler sonography was used to determine the pattern of anterograde and retrograde flow. The ratio of blood volumes was calculated with a vision analysis software. First, performance of the developed algorithm was validated by comparing it with commercial Doppler sonography data. Doppler sonography was performed for an artificial vessel to analyze the steal flow. Results A total of 58 patients with steal flow were enrolled in this study. Of these patients, 23 did not have a difference in fingertip temperature between both sides. The median difference in temperature of 35 patients was 0.8°C (range, 0.3−1.9°C). The ratio of retrograde flow volume/antegrade flow volume in patients with the presence of temperature difference was significantly higher compared to that in patients without the temperature difference ( p < .001). The ROC curve for the difference in flow volume had an AUC of 0.770. The optimal cutoff of difference in the flow volume between the two groups was 0.24 (sensitivity of 91.4 % and specificity of 52.2%). The flow volume difference was significantly positively correlated to temperature difference (r = 0.487, p < .003). Conclusion Our algorithm could measure steal flow volume of a bidirectional waveform by antegrade arterial flow and retrograde reversal flow.
LogMyScan: A pilot evaluation study of a mobile phone–based ultrasound logbook application
Authors: Jarman Robert David , Anderson David , Richards Simon , Davison Tyrone , Fenton Siobhan , Batterham Alan , Ryan Cormac , Cosson Philip 
Published: May 2024

Introduction: We developed a mobile phone logbook application called LogMyScan. The study objectives were to evaluate a number of domains as per the technology acceptance model. Methods: A prospective pilot cohort study was conducted using a version of LogMyScan and reported according to Statement on Reporting of Evaluation studies in Health Informatics. Prospective participants were directed to a website which provided information and links. Participants were recruited via email distribution lists and social media. A task list was provided, which included entering simulated scan data and navigating the application, prior to completing a questionnaire. Questions were aligned to technology acceptance model domains, and Cronbach’s alpha was calculated to assess reliability. Results: There were 49 participants and 7 were unable to complete the image upload and editing step. Levels of agreement for usability, educational and governance/security aspects were generally good. The desirability of existing and proposed features was high for images and video clip handling, feedback and reflection and less for motivational notifications and benchmarking. Comments identified some limitations and issues on the Android platform. Cronbach’s alpha demonstrated good to excellent reliability: 0.87 (95% confidence interval, 0.79–0.91) for usability, educational and governance/security and 0.86 (95% confidence interval, 0.78–0.91) for desirability of existing and proposed features. Conclusion: There was generally high perceived ease of use, usefulness, attitude towards use and behavioural intention to use LogMyScan. Further research is needed to evaluate LogMyScan for future iterations, allowing recruitment of a larger number of participants and evaluating user expectations prior to using, and at timed intervals after using.