bluuebunny/crossref_metadata_2025_split huggingface dataset:
การศึกษาองค์ประกอบของการจัดการโลจิสติกส์เพื่อการท่องเที่ยวแบบยั่งยืนของอุทยานธรณีสตูล
Authors: อนุรักษากรกุล พรรณิภา , เฮงพัฒนา สุวิมล 
Published: May 2024

การศึกษาองค์ประกอบของการจัดการโลจิสติกส์เพื่อการท่องเที่ยวแบบยั่งยืนอุทยานธรณีสตูล เพื่อหาแนวทางการจัดการโลจิสติกส์เพื่อการท่องเที่ยวของอุทยานธรณีสตูลแบบยั่งยืน เป็นการวิจัยเชิงคุณภาพ โดยใช้ข้อมูลทุติยภูมิจากแผนแม่บทการบริหารจัดการอุทยานธรณีสตูล ข้อมูลการท่องเที่ยวของจังหวัดสตูล แผนยุทธศาสตร์การพัฒนาจังหวัดสตูล ตลอดจนเอกสารจากกรมทรัพยากรธรณี ข้อมูลปฐมภูมิด้านอุปทานที่ใช้ในการวิเคราะห์ประกอบด้วย การลงพื้นที่สำรวจสถานการณ์การจัดการ โลจิสติกส์เพื่อการท่องเที่ยว 28 แห่งของอุทยานธรณีสตูล การสัมภาษณ์เชิงลึกผู้ที่เกี่ยวข้องทั้งภาครัฐและภาคเอกชน ข้อมูลปฐมภูมิด้านอุปสงค์จากการสำรวจนักท่องเที่ยวที่มาเที่ยวอุทยานธรณีสตูล จำนวน 400 คน การวิเคราะห์ข้อมูลใช้สถิติเชิงพรรณนาและการวิเคราะห์เนื้อหา
ผลการวิจัยพบว่า องค์ประกอบของการจัดการโลจิสติกส์เพื่อการท่องเที่ยวแบบยั่งยืนของอุทยานธรณีสตูลมี 4 องค์ประกอบหลัก คือ การขนส่ง สิ่งอำนวยความสะดวกแก่นักท่องเที่ยว ทรัพยากรทางธรณีวิทยาและภูมิทัศน์ และการจัดการสิ่งแวดล้อม โดยใช้ปัจจัยสนับสนุน 3 ด้าน ได้แก่ เทคโนโลยีและสารสนเทศ นวัตกรรม และการพัฒนาที่ยั่งยืน แนวทางการพัฒนาในแต่ละองค์ประกอบคือ 1) การขนส่ง ชุมชนแต่ละอปท.ควรลงทุนให้บริการรถโดยสารสาธารณะในรูปรถสองแถวไม้ที่มีเอกลักษณ์ของอุทยานธรณีสตูล สร้างแอพลิเคชั่น Geopark Grab and Guide 2) สิ่งอำนวยความสะดวก สร้างเครือข่ายชุมชนให้บริการบ้านพักแบบโฮมสเตย์เพื่อรองรับนักท่องเที่ยวในช่วงฤดูกาลท่องเที่ยว ร้านอาหารควรมีตราฮาลาล 3) ด้านทรัพยากรทางธรณีวิทยาและภูมิทัศน์ พัฒนาภูมิทัศน์โดยรอบพื้นที่อุทยานธรณีสตูล คำนึงถึงรูปลักษณ์และสถาปัตยกรรมดั้งเดิม มีการวิจัยเพื่อประเมินถึงความเต็มใจที่จะจ่ายของนักท่องเที่ยวเพื่อกำหนดค่าธรรมเนียมในการเข้าอุทยานและแหล่งท่องเที่ยวอย่างเหมาะสม แหล่งท่องเที่ยวที่อยู่ในเขตพื้นที่ที่ดูแลโดยหน่วยงานราชการต้องมีการบูรณาการการทำงานร่วมกัน และ 4) การจัดการสิ่งแวดล้อม องค์การปกครองส่วนท้องถิ่นต้องร่วมกันรับผิดชอบในการป้องกันมลภาวะ โดยเฉพาะในฤดูกาลท่องเที่ยวที่มีนักท่องเที่ยวจำนวนมาก
Selective Serotonin Reuptake Inhibitors Response and the Impact of CYP2C19 Metabolizer Status
Authors: Editorial Staff  
Published: May 2024

A particular class of antidepressants called selective-serotonin-reuptake-inhibitors (SSRIs) are subjected to altered metabolism as a result of variations in the CYP2C19 gene. Clinicians do take into account the CYP2C19 variations whilst making a pharmacogenomic recommendation. However, the clear links between the efficacy and safety of the drugs to the genetic variations in metabolism are yet to be established. Campos et al, intended to address this question by investigating CYP2C19 polymorphisms and the associated metabolism as well as patient-reported response in a cohort of 9531 patients subjected to SSRIs as part of their regimen. CYP2C19 alleles were the determining factor for metabolizer status. Rapid metabolizers demonstrated higher tolerability but poor metabolizers reported higher efficacy, across all medications. Greater differences were seen in reporting adverse effects for sertraline in various metabolizer groups. The results for tolerability, efficacy and adverse effects, and metabolizer state were in line with previous predictions. Their study did not see slow metabolizers to be at a greater risk for side effects without clinical titration adjustments. Still, both interventional and longitudinal studies such as randomized clinical trials including the whole spectrum of metabolizers are essential to determine the association between CYP2C19 metabolizers and the effects on SSRI treatment efficacy and adverse effects. Pharmacogenomics J. 2022 Mar;22(2):130-135.
Plasma Level Determination and Pharmacogenetics of Clozapine
Authors: Editorial Staff  
Published: May 2024

Sanguesa et al., undertook an investigation to discern the differences in the levels of Clozapine (CLZ) in plasma and determine the pharmacogenetic and sociodemographic factors that influence it as well as introduce these tools in a clinical setting. In a group of 23 patients diagnosed with psychotic disorders CLZ concentration in plasma were measured alongside CLZ pharmacokinetic and pharmacodynamic parameters. Their findings revealed that smoking status, age, and weight were significantly associated with mean concentration/dose ratio (C/D). Gender and mean CLZ concentrations also demonstrated a significant difference. Smokers having the genotype rs762551 AA had a significantly lower C/D ratio. The authors concluded that measuring CLZ levels in plasma with pharmacogenetics as well as classical factors produced greater individualization of treatment. Per Med. 2022 May;19(3):181-192.
LIFE HISTORY PARAMETERS OF MELON FRUIT FLY, BACTROCERA CUCURBITAE (COQUILLETT) (DIPTERA: TEPHRITIDAE) ON FOUR ECONOMICALLY IMPORTANT VEGETABLES
Authors: Niaz Hussain Khuhro  , Muhammad Abubakar  , Qadir Bux Pirzado  , Qadeer Ahmed Soomro  , Muhammad Ibrahim Kubar  , Muhammad Usman Asif  , Memon Raza Muhammad 
Published: May 2024

The majority of plant species that are used for consumption and medicinal purposes belongs to Cucurbitaceae. These vegetables are attacked by several insect pests including Tephritid flies. Keeping in view, four economically important cucurbit vegetables such as sponge gourd; Luffa aegyptiaca, bitter gourd; Momordica charantia, musk melon; Cucumis melo, and bottle gourd; Lagenaria siceraria were selected to investigate the life-history parameters of Bactrocera cucurbitae (Coq.) (Diptera: Tephritidae) under laboratory conditions. For this purpose, B. cucurbitae was reared in the laboratory on each host vegetable and egg hatchability %, egg incubation period, larval survival (%), duration (days), length and width of larvae, pupal parameters, male-female ratio, and age-specific fecundity were recorded. The results showedno statistical difference in hatchability percentages, larval duration, and pupal survival (%) in all tested vegetables. However, greater length and width of larvae were recorded when the B. cucurbitae larvae were provided with bottle gourd. Moreover, maximum pupal recovery was recorded in bottle and sponge gourd among all the tested vegetables. Maximum females were also recorded in bottle gourd. Adult longevity and fecundity were significantly affected by the host. Maximum female longevity (52 days) was recorded when B. cucurbitae were provided with bottle gourd and minimum (41 days) on sponge gourd. Similarly, maximum fecundity (823 eggs) was also recorded when maggots were fed on bottle gourd and the lowest (611 eggs) on a sponge gourd. In conclusion, Bottle gourd is the most preferable and nutritious host among all the tested vegetables and needs effective management strategies for B. cucurbitae. The output of the present studies would be helpful for the development of an effective integrated pest management (IPM) program for B. cucurbitae in a variety of vegetables.
ASSESSING GENE ACTION AND COMBINING ABILITY IN Brassica napus L. UNDER DROUGHT STRESS CONDITIONS, AN EFFORT TOWARDS BREEDING RESILIENT VARIETIES
Authors: Humera Razzaq  , Saman Arshad  , Muhammad Abu-Bakkar Azmat  , Amir Shakil  , Urfa Sehar  , Sana-e-Mustufa  , Amna Kanwal  , Muhammad Shaban  
Published: May 2024

Drought stress is the limiting factor in productivity as well as quality of any crop. Drought stress effects are crucial in Brassica napus but severity depends on the duration, intensity and developmental stages. İn the present study, eight drought tolerant lines and three drought sensitive testers were crossed in the line × tester fashion. Developed germplasm accesions with their parents were evaluated under standard and drought stress conditions in RCBD having split plot arrangements. Various qualitative and quantitative parameters were recorded. Among the parents, ZMR-2, Dunkled, and Garchi exhibited potential based on their general combining ability (GCA) under both control and drought stress conditions.. The best cross combinations, identified through significant positive values for specific combining ability (SCA), included ZMR-2 × ZMR-18, Winner × ZMM-12 and Garchi × ZMR-18 under control and drought stress treatment T1. Similarly, G-51 × ZMR-18, Dunkled × ZMR-18, and DGL × ZMR-18 performed well under drought stress treatment T2. GCA variance surpassed the SCA varinace, depicting the presence of additive gene action in studied material. So, these crosses could be selected readily without moving towards segregating generations in the future drought breeding programes.
Mach, Russell, and Scientific Philosophizing: Re-visiting the Realistic Empiricism of Evolutionary Culture
Authors: Omar Majeda Ahmad 
Published: May 2024

Ernst Mach’s and Bertrand Russell’s philosophical outlooks contributed to shaping the philosophy of science of the 20th century. Mach is a philosophical interpreter of science, a positivist, and a historian, considering the general principles of science as condensed economic descriptions of observed facts. Russell held a view of the nature and relation of philosophy to science and to logic that can be described as essentially consistent. In this article, the aim is to explore how both Mach and Russell defended the classical version of “Neutral Monism”. Since it was developed as a reaction to the mechanical philosophy of nature, Neural Monism also emerged along with scientific psychology in the late 19th century. The attempt in this article is to examine their versions of neutral monism and emphasize their differences and convergences.
Land, biological and economic evaluation of intercropping systems involving barley (Hordeum vulgare), Indian mustard (Brassica juncea) and chickpea (Cicer arietinum) under different spatial arrangements
Authors: BHAGAT SINGH  , A.K. DHAKA  , SATISH KUMAR  , SAMUNDER SINGH  , MUKESH KUMAR  
Published: May 2024

A field experiment was conducted during the winter (rabi) seasons of 2011–12 and 2012–13 at Hisar, Haryana, in randomized block design with 9 treatments replicated thrice, to evaluate the intercropping of Indian mustard [Brassica juncea (L.) Czernj & Cosson] and chickpea (Cicer arietinum) with barley (Hordeum vulgare L.) in re placement series. Results revealed that seed and straw yields of barley was reduced in barley + Indian mustard intercropping system as compared to barley + chickpea because Indian mustard was found to be more competi tive and dominant over barley, as evident from higher partial relative crowding coefficient (RCC), competitive ratio (CR), actual yield loss (AYL) and positive aggresivity (A) values of Indian mustard in all the planting patterns com pared to barley and chickpea. Among the intercropping treatments, barley + Indian mustard (6 : 3) was found most economical and efficient intercropping system with the highest barley-equivalent yield (BEY, 7.93 t/ha), land-use efficiency (LUE, 135%), area-time equivalent ratio (ATER, 1.34), land-equivalent ratio (LER, 1.36), land-euivalent coefficient (LEC, 0.44), crowding coefficient (K, 5.82), actual yield loss (AYL, + 1.10), intercropping advantages in dex (IAI, + 3624.3), monetary advantage index (MAI, + 17,975.4), income-equivalent ratio (IER, 1.24), system productivity index (SPI, 65.4), relative net returns index (RNRI, 1.27), monetary-equivalent ratio (MER, 1.33), net returns ( 56,321/ha), benefit: cost rato (B:C, 3.41) and profit margin (71%). Among different row patterns, on the basis of total crop-performance ratio (CPR) values, barley intercropped with either of the intercrop at 6:3 row ratio performed better. Hence barley + Indian mustard (6:3) intercropping system can be a best option to get more mon etary returns and resource-use efficiency.
Phytochemical screening and evaluation of the anti-venom effect of leaves extracts of Vitex negundo
Authors: Dinesh Jindal  , Raghvendra S. Bhadauria  
Published: May 2024

The number of snake envenomation cases is estimated to be more than 5 million per year. Out of these cases, approximately 1,00,000 individuals experience severe complications. The objective of the current research is to investigate the effectiveness of local plant extracts from the western ghats of India in countering snake venom. The medicinal plant Vitex negundo has been traditionally used by healers in India to treat snakebite victims. Prior to injection, extract from the Vitex negundo plant was incubated at 37°C for 30 minutes. The study revealed that doses ranging from 0.15-0.17 mg of Vitex negundo extracts completely neutralized the lethal effects of V. russelli venom, while doses of 0.16-0.19 mg neutralized the lethal effects of Najanaja venom. In rats, the minimum edematic dose of the venom was found to be 4μg. Notably, significant inflammation was observed 1 hour after venom injection, with maximum inflammation occurring at 180 minutes. Furthermore, plant extracts administered at doses of 100mg/kg, 200mg/kg, and 400mg/kg exhibited significant activity compared to the control group. The minimum percentage inhibition was 29.13% and 27.1% at 100mg/kg, 58.18% and 57.21% at 240 minutes for 400mg/kg, and 60.89% for Vitex negundo with standard polyvalent antivenom. against V. Russelli and Najanaja venom, respectively.
Radioprotection Compliance Rules Study in Dakar's Hospitals, Senegal
Authors: Ndoye EL Hadji Oumar , Diop Al Housseynou , Badiane Serigne Moussa 
Published: May 2024

This work aims to promote greater safety in the use of X-rays in our hospitals. The effects of radiation have continued to arouse keen interest mixed with concern. Due to their ionizing power, these radiations lead to cascades of reactions in the body causing genetic mutations, cancer phenomena and even cell death, among others. We thus distinguish between threshold effects (deterministic) and random effects (stochastic). This work is a quantitative study based on a questionnaire intended for majors in radiology services in Dakar.
This study was carried out in the Dakar region over a period of two (02) months from July 15, 2022 to September 15, 2022. By analyzing the results, we’ve noted that standard radiography and computed tomography are the two most frequently performed radiological examinations in all the services studied with respectively 60.9 o/o and 30.4 o/o of the radiological examinations carried out daily. It is appeared that radiation protection in radiology departments has limits. It is therefore urgent to overcome them and to encourage the development of radiation protection in parallel with the evolution of the technical platform. Compliance with the rules and regulations constitutes a requirement for the protection of people exposed to ionizing radiation. The national radiation protection authority should take steps to harmonize the control protocols for radiology department equipment for optimal monitoring of radiation protection measures. It would be important to install a maintenance unit in each health structure with a radiology department which would be under the responsibility of the national authority responsible for radiation protection.
Sanctions are provided for in the event of breaches of laws and regulations by the Senegalese authorities.
Relations of proactive and reactive dimensions of aggression to overt and covert narcissism in nonclinical adolescents
Authors: Fossati Andrea , Borroni Serena , Eisenberg Nancy , Maffei Cesare 
Published: November 2009

AbstractIn recent years, there has been increasing acknowledgment of the multidimensionality of narcissism and that different types of narcissism may relate differently to other domains of functioning. Similarly, aggression—a frequently discussed correlate of narcissism—is a heterogeneous construct. In this study, the relations of proactive and reactive aggression with overt and covert manifestations of narcissism were examined in a sample of 674 Italian high school students (mean age=15.5 years, SD=2.1 years). Overt narcissism was positively related to both proactive and reactive subtypes of aggression, whereas covert narcissism related only to reactive aggression. Vanity, Authority, Exhibitionism, and Exploitativeness were the components of overt narcissism related to Proactive Aggression (all remained unique correlates when controlling for Reactive Aggression), whereas Reactive Aggression was associated with the Exhibitionism, Superiority, and Entitlement subscales (only the latter was uniquely related when controlling for Proactive Aggression). Aggr. Behav. 36:21–27, 2010. © 2009 Wiley‐Liss, Inc.
Evaluating Carrier Accumulation in Degraded Bulk Heterojunction Organic Solar Cells by a Thermally Stimulated Current Technique
Authors: Kawano Kenji , Adachi Chihaya 
Published: November 2009

AbstractHere, the initial photo‐degradation of encapsulated P3HT:PCBM bulk heterojunction organic solar cells is investigated. The degraded device is recovered by thermal annealing treatment. Thermally stimulated current measurements reveal that the cause of photo‐degradation is carrier accumulation and that the degraded organic solar cell has two broad trap levels, of 0.71 and 0.81 eV. These traps are independent of the thickness of the photoactive layers, the mixing ratio of the photoactive materials and the cathode materials. In addition, it is confirmed that there is a close relationship between the degree of degradation and the amount of accumulated charge carriers.
Gold‐ and Silver‐Catalyzed Intramolecular Hydroamination of Terminal Alkynes: Water‐Triggered Chemo‐ and Regioselective Synthesis of Fused Tricyclic Xanthines
Authors: Ye Deju , Zhang Xu , Zhou Yu , Zhang Dengyou , Zhang Lei , Wang Hengshuai , Jiang Hualiang , Liu Hong 
Published: November 2009

AbstractA simple, convenient and green synthetic approach to diverse fused tricyclic xanthines has been developed via gold(I) complex‐catalyzed intramolecular hydroamination or silver(I)‐catalyzed isomerization‐hydroamination of terminal alkynes under microwave irradiation in water. The first synthesis of N9‐annelated xanthines has also been reported.
Nine Times Fluoride can be Good for your Syntheses. Not just Cheaper: Nonafluorobutanesulfonates as Intermediates for Transition Metal‐Catalyzed Reactions
Authors: Högermeier Jens , Reissig Hans‐Ulrich 
Published: November 2009

AbstractHow much fluoride is good for a strong electron‐withdrawing effect? In this review we summarize recent results on the use of perfluoroalkanesulfonates, in particular of the cost effective nonafluorobutanesulfonates (nonaflates), in transition metal‐catalyzed reactions and a few other typical transformations. During the last decade many advantages over the commonly used triflates have been discovered. The generation of alkenyl and (het)aryl nonaflates and their applications in metal‐catalyzed processes such as Heck, Suzuki, Sonogashira, Stille, and Negishi couplings or amination reactions are described. Although far from a systematic investigation, all the presented results clearly demonstrate the many advantages of nonaflates and of similar higher fluorinated sulfonates in laboratory and industrial scale organic synthesis.
Enantioselective Electrophilic Amination of α‐Cyanothioacetates with Azodicarboxylates Catalyzed by an Axially Chiral Guanidine Base
Authors: Terada Masahiro , Tsushima Daisuke , Nakano Megumi 
Published: November 2009

AbstractAn enantioselective electrophilic amination of α‐substituted cyanothioacetates with azodicarboxylate is demonstrated using an axially chiral guanidine as a chiral Brønsted base catalyst. The corresponding product, having a quaternary stereogenic center at the α‐carbon atom, is formed in excellent enantioselectivity.
The mean measure of divergence: Its utility in model‐free and model‐bound analyses relative to the Mahalanobis D2 distance for nonmetric traits
Authors: Irish Joel D. 
Published: November 2009

AbstractThe mean measure of divergence (MMD) distance statistic has been used by researchers for nearly 50 years to assess inter‐sample phenetic affinity. Its widespread and often successful use is well documented, especially in the study of cranial and dental nonmetric traits. However, the statistic has accumulated some undesired mathematical baggage through the years from various workers in their attempts to improve or alter its performance. Others may not fully understand how to apply the MMD or interpret its output, whereas some described a number of perceived shortcomings. As a result, the statistic and its sometimes flawed application(s) have taken several well‐aimed hits; a few researchers even argued that it should no longer be utilized or, at least, that its use be reevaluated. The objective of this report is to support the MMD, and in the process: (1) provide a brief history of the statistic, (2) review its attributes and applicability relative to the often‐used Mahalanobis D2 statistic for nonmetric traits, (3) compare results from MMD and D2 model‐free analyses of previously‐recorded sub‐Saharan African dental samples, and (4) investigate its utility for model‐bound analyses. In the latter instance, the ability of the D2 and other squared Euclidean‐based statistics to approximate a genetic relationship matrix and Sewall Wright's fixation index using phenotypic data, and the inability of the MMD to do so, is addressed. Three methods for obtaining such results with nonlinear MMD distances, as well as an assessment of the fit of the isolation‐by‐distance model, are presented. Am. J. Hum. Biol., 2010. © 2009 Wiley‐Liss, Inc.
Selection in utero: A biological response to mass layoffs
Authors: Catalano Ralph , Zilko Claire E. Margerison , Saxton Katherine B. , Bruckner Tim 
Published: November 2009

AbstractMost research describing the biological response to unemployment appears appropriately motivated by clinical or public health concerns and focuses on death, disease, and medical care. We argue that expanding the work to include other outcomes could contribute to basic science. As an example, we use the response to mass layoffs to discriminate between two explanations of low ratios of male to female live births in stressed populations. One explanation asserts that ambient stressors reduce the ratio of males to females conceived. The other argues that the maternal stress response selects against males in utero. We show that selection in utero better explains the observed data. We conclude that human adaptation to the economic environment deserves scrutiny from a wider array of scientists than it now receives. Am. J. Hum. Biol., 2010. © 2009 Wiley‐Liss, Inc.
Synthesis and characterization of alumina flakes/polymer composites
Authors: Afsharimani Nasima S. , Iraji Zad Azam , Tafreshi Majid Jafar , Salartayefeh Saeed 
Published: November 2009

AbstractAlumina flakes were prepared by solution combustion method and milled to provide powder. XRD and SEM data exhibited microsized flakes with 100 nm thickness and nanosized grains. Then the powders were dispersed in polystyrene (PS) and poly methyl methacrylate (PMMA) matrixes and thin sheets of composites were produced by solution method. Mechanical properties of the composites were characterized using tensile test and their fracture surfaces, elemental composition and hydrophobic property were tested by SEM, EDX and contact angle techniques, respectively. The results exhibited better mechanical properties compared to pure polymer samples i.e. the elastic modulus in PMMA and PS composites, were increased about 107 and 109%, respectively. In addition the composite surfaces became more hydrophobic than pure polymer systems. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010