bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the drivers of supply chain sustainability: An internal and external configuration perspective
Authors: Yin Weili 
Published: April 2024

AbstractThe global supply chains sustainability and viability has been severely impacted due to the emergence of black swan events such as COVID‐19. Previous studies have examined how to enhance supply chain sustainability from a single internal capability perspective or an external relationship perspective, few studies have examined the combined effects of internal and external factors to enhance supply chain sustainability. To fill this research gap, this study investigates the multivariate relationship from internal capabilities and external relationships mutually complementary perspective to improve supply chain sustainability. Grounded on dynamic capabilities theory and relational view, we put forward the supply chain dynamic capability construct under the internal perspective, and relationship construct with supply chain members under the external perspective. Based on the configuration theory, 270 data from enterprises were analyzed using fsQCA (fuzzy set qualitative comparative analysis), and the results shows that: first, there is no necessary condition for generating high supply chain sustainability, which means that individual factors do not lead to high supply chain sustainability; second, this study identified two paths to achieve high supply chain sustainability: capability‐driven and relationship‐driven, which reflects the multiple paths and complex mechanisms to achieve high supply chain sustainability; third, this study finds the important role of supply chain dynamic reconfiguring capability in forming high supply chain sustainability. These results can provide some theoretical guidance for enterprises to improve supply chain sustainability and achieve high quality economic development.
A Naphthalimide Based “Turn‐ON” Probe for Wash‐Free Imaging of Lipid‐Droplet in Living Cells With an Excellent Selectivity
Authors: Michel Laurane , Durand Philippe , Chevalier Arnaud 
Published: April 2024

AbstractThe impacts of dimethylation of 4‐Amino‐1,8‐Naphthalimide (ANI) on its photophysical properties are reported. The resulting 4‐DiMe‐ANI displays completely different fluorescence properties, conferring it ability to selectively label lipid droplets in living cells. A comprehensive photophysical study revealed that this selectivity arises from an Internal Charge Transfer favored in lipophilic media to the detriment of a non‐emissive TICT in more polar media. This results in a very high “LDs/Cytosol” signal ratio, enabling LDs to be imaged with an excellent signal‐to‐noise ratio, and positioning its performance above that of the BODIPY 493/503 commonly used to image LDs.
Exploring the Role of Central Metals in Bulky Phthalocyanines for Dye‐Sensitized Solar Cells
Authors: López‐Duarte Ismael , Kawata Takahiro , Urbani Maxence , Dreano Melanie , Kimura Mutsumi , Martínez‐Díaz M. Victoria , Torres Tomás 
Published: April 2024

AbstractTwo series of metallo‐(Zn(II), Mg(II), and Ru(II)) and free‐base phthalocyanines (Pcs) with a carboxyl anchoring group and well‐established bulky peripheral substituents (either tert‐butyl or bulky 2,6‐diisopropylphenoxy) were synthesized and tested as sensitizers in dye‐sensitized solar cells (DSSCs). The trend of photovoltaic efficiencies (PCEs) for free‐base and metallo Pcs followed the order Zn(II)Pc>Mg(II)Pc≫H2Pc ≈ Ru(II)Pc regardless of the peripheral substitution. Higher efficiencies (4.95 versus 3.63 for the Zn(II) derivatives) were achieved with Pcs bearing the bulkier 2,6‐diisopropylphenoxy group, indicating a lower aggregation and more suitable HOMO‐LUMO levels. Furthermore, these derivatives showed a morelevant influence of the metal on the PCE values (from the highest 4.95 for the Zn(II)Pc to the lowest 0.23 for the Ru(II)Pc. In both series, the best PCEs observed with the Zn(II) derivatives were mainly due to their highest Jsc values. The lowest efficiencies found for the free‐bases and Ru(II) derivatives were attributed to a mismatch between their LUMO levels and the conduction band of the TiO2,and lower light‐harvesting capabilities, respectively. In conclusion, Zn(II) derivatives are still the best Pc candidates to use as sensitizers in molecular photovoltaics.
Advanced Insulin Synthesis by One‐pot/Stepwise Disulfide Bond Formation Enabled by S‐Protected Cysteine Sulfoxide
Authors: Hidaka Kota , Kobayashi Daishiro , Hayashi Junya , Denda Masaya , Otaka Akira 
Published: April 2024

AbstractAn advanced insulin synthesis is presented that utilizes one‐pot/stepwise disulfide bond formation enabled by acid‐activated S‐protected cysteine sulfoxides in the presence of chloride anion. S‐chlorocysteine generated from cysteine sulfoxides reacts with an S‐protected cysteine to afford S‐sulfenylsulfonium cation, which then furnishes the disulfide or reversely returns to the starting materials depending on the S‐protection employed and the reaction conditions. Use of S‐acetamidomethyl cysteine (Cys(Acm)) and its sulfoxide (Cys(Acm)(O)) selectively give the disulfide under weak acid conditions in the presence of MgCl2 even if S‐p‐methoxybenzyl cysteine (Cys(MBzl)) and its sulfoxide (Cys(MBzl)(O)) are also present. In contrast, the S‐MBzl pair yields the disulfide under more acidic conditions in the presence of a chloride anion source. These reaction conditions allowed a one‐pot insulin synthesis. Additionally, lipidated insulin was prepared by a one‐pot disulfide‐bonding/lipidation sequence.
Access to Enantioenriched Allylic Alcohols via Peptide‐Mimic Phosphonium Salt‐Catalyzed Asymmetric Aerobic Hydroxylation
Authors: Che Jixing , Fang Siqiang , Liu Zanjiao , He Jiajia , Zheng Jia‐Yan , Wang Fan , Wang Tianli 
Published: April 2024

Comprehensive SummaryThe development of catalytic asymmetric methods that enable access to value‐added functionalities or structures, exemplified by allylic alcohols, is a highly interesting yet challenging topic from both academic and industrial perspectives. However, before recent advances in chemical catalysis, there were scarce protocols toward constructing enantioenriched tertiary allylic alcohol scaffolds. In this context, peptide‐mimic phosphonium salts were found to be highly efficient in catalytic asymmetric α‐hydroxylation of α,β‐unsaturated and/or β,ϒ‐unsaturated compounds with satisfactory regio‐ and stereochemical outcomes (up to 97% yield and 95% ee). This methodology tolerates a broad array of substrates and thus provides an expeditious and unified platform for the assembly of enantioenriched tertiary allylic alcohols by avoiding the use of additional reductants and expensive metal catalysts. Furthermore, the power of this protocol is enlarged by simple conditions and the use of air as a source of hydroxyl functionality.
I2–DMSO‐Mediated Multicomponent [2+1+1+1] Annulation Reaction via Ethyl Nitroacetate C—NO2 Bond Cleavage as a C1 Synthon: A Route to Multisubstituted β‐Pyrrolidinones Derivatives with a Quaternary Center
Authors: Yu Zhi‐Cheng , Shen Xi , Zhou You , Chen Xiang‐Long , Wang Li‐Sheng , Wu Yan‐Dong , Wu An‐Xin 
Published: April 2024

Comprehensive SummaryA [2 + 1 + 1 + 1] cyclization reaction has been developed for the synthesis of multisubstituted β‐pyrrolidinones from commercially available aryl methyl ketones, primary amines, and ethyl nitroacetate. In this I2–DMSO‐meditated process, the C—NO2 bond of ethyl nitroacetate is cleaved, affording a C1 synthon, and the formation of two C—C and two C—N bonds and a quaternary carbon center are constructed in one pot. This method has good substrate compatibility and permits the late‐stage modification of pharmaceutical compounds.
Sulfonamide Bioisosteres of Niclosamide Enhance Antibacterial Activity of Colistin and Bacitracin
Authors: Berry Liam , Ramirez Danyel , Domalaon Ronald , Schweizer Frank 
Published: April 2024

AbstractMulticomponent therapy combining antibiotics with enhancer molecules known as adjuvants is an emerging strategy to combat antimicrobial resistance. Niclosamide is a clinically relevant anthelmintic drug with potential to be repurposed for its inherent antibacterial activity against Gram‐positive bacteria and its ability to potentiate the antibacterial activity of colistin against susceptible and resistant Gram‐negative bacteria. Herein, sulfonamide analogs of niclosamide were prepared and found to enhance colistin activity against Gram‐negative bacteria. The ability of niclosamide and the new sulfonamide analogs to synergize with bacitracin against vancomycin‐resistant Enterococcus faecium was also discovered.
Recent progress on construction and applications of metal‐organic frameworks‐based materials for lithium‐ion batteries and supercapacitors
Authors: Wei Dan , Zhang Lingling , Wang Yiming , Qiu Shujun , Luo Yumei , Zou Yongjin , Xu Fen , Sun Lixian , Chu Hailiang 
Published: April 2024

AbstractMetal‐organic frameworks (MOFs), a special sort of three‐dimensional crystalline porous lattices composed of organic multi‐site connectors and metal nodes, are characterized by unique porosity and high specific surface area, which have attracted a wide range of interest as electrode materials for the electrochemical energy storage devices in recent years. In this contribution, we outline the current research progress on the construction of pristine MOFs, MOF composites, and MOF derivatives and their applications as electrode materials in supercapacitors (SCs) and lithium‐ion batteries (LIBs). Specifically, we discuss the shortcomings of MOFs‐based electrode materials for SCs and LIBs. The innovative work on performance improvements by combining MOFs with other conductive materials and derivating MOFs into metal sulfides, metal oxides, metal phosphides, and porous carbon is also presented in detail. Finally, our perspectives on the challenges in the future for a grasp of the potential mechanisms are tentatively provided. This review will inspire more developments and applications of MOFs‐based electrode materials for electrochemical energy storage.
Atropisomeric Foldamers
Authors: Ansari Saima , Knipe Peter C. 
Published: April 2024

AbstractThis concept article explores the emerging role of atropisomerism in foldamer chemistry, a field focussed on oligomers that adopt well‐defined conformations through non‐covalent interactions. Atropisomerism introduces a novel dimension to foldamer design by restricting rotational freedom around single bonds to dictate molecular shape with precision. Despite the prevalence of atropisomeric bonds in organic synthesis, their application within foldamers remains underexplored. Here, we discuss key developments in both backbone and sidechain atropisomerism, and suggest future directions for atropisomeric foldamers in the context of a recent surge in atropselective synthetic methods. We propose that judicious use of atropisomerism may serve as a transformative tool in the construction of shape‐defined macromolecules.
Photo‐Responsive TiO2‐Gold Nanoparticle‐Polymer Nanohybrid Exhibits Photothermal, Thermo‐Release, and Photocatalytic Effects
Authors: Consoli Grazia M. L. , Forte Giuseppe , Maugeri Ludovica , Petralia Salvatore 
Published: April 2024

AbstractThe development of multi‐responsive nanohybrid systems that combine photothermia, thermo‐responsive effects and photocatalysis is a challenging topic in the research of multifunctional materials with a large field of applications. Here, we report the first example of a three‐components light‐responsive nanosystem consisting of titania, gold nanoparticles and poly‐N‐isopropylacrylamide (TiO2‐Au‐PNM). The hybrid nanostructure exhibited photothermal conversion effect upon green‐light excitation and capacity to entrap methylene blue and curcumin selected as cargo models. The formation of the nanohybrid–cargo adducts, the photothermal‐controlled cargo release triggered by green‐light irradiation (532 nm) and mediated by lower critical solution temperature (LCST), as well as the photocatalytic effect prompted by UV‐light excitation (300 nm) were demonstrated by spectroscopic techniques. The mechanism involved in the interaction of the polymeric component with the cargos was investigated by molecular modelling calculations.
Sustainable supply chain management's impact on triple bottom line performance: Does the firm size matter?
Authors: Jum'a Luay , Zimon Dominik , Sroufe Robert , Tyan Jonah 
Published: April 2024

AbstractCompanies worldwide are moving towards sustainability by focusing on its three dimensions: environmental, economic, and social sustainability. This study explores how sustainable supply chain management (SSCM) takes the changing role to affect these three dimensions. Since organizations vary in size, we post and test relationships regarding how firm size can impact the implementation of SSCM practices as a moderator. We posit an empirical research model and test this using structural equation modeling with survey data from 392 managers across various Jordanian manufacturing firms. This study assessed the link between five categories of SSCM practices and TBL performance. We found that firm size is critical and moderates the positive SSCM relationship with economic and social performances. Results shed new light on SSCM and its impacts on environmental, economic, and social performance. According to the study findings, environmental management practices and supply chain integration influenced all sustainability dimensions, whereas socially inclusive community practices influenced none. Furthermore, operations had an impact on economic sustainability. Finally, socially inclusive employee practices had a significant impact on both environmental and economic sustainability. Findings show that when implementing SSCM, larger firms perform better on multiple sustainability measures compared to smaller firms. The model's integration of firm size as a moderator provides additional insights regarding the SSCM construct and its change agent role in stimulating sustainable development.
A passivity control and developed nonlinear disturbance observer for boost converter with constant power load in DC microgrid
Authors: Abdolahi Mohsen , Adabi Jafar , Mousazadeh Mousavi Seyyed Yousef 
Published: April 2024

SummaryThis paper presents an adaptive nonlinear control scheme to ensure the stability of a boost converter in a DC microgrid that supplies a constant power load (CPL) and a resistive load. The proposed controller comprises a passivity‐based control (PBC) and a Nonlinear Disturbance Observer‐Based Robust Control (NDOBRC). The PBC guarantees the overall stability of the proposed controller, whereas the NDOBRC compensates for various sources of disturbances and uncertainties in the system, such as CPL power. The large‐signal stability of the PBC is established using the Lyapunov function. Simulation and experimental results demonstrate the effectiveness of the proposed controller in terms of superior performance compared to the PI method.
Design and implementation of a hybrid piezoelectric, radio frequency, solar, and thermal energy‐harvesting system for portable medical devices
Authors: Noohi Mostafa , Mirvakili Ali 
Published: April 2024

AbstractToday, energy harvesting has developed into a technique from which various aspects are still hidden. By extracting energies from the environment and even the human body, and converting them into electrical energy, we can supply power to low‐consumption electronic devices. Energy harvesting works by inhibiting small amounts of ambient energies; otherwise, it is wasted in other forms such as heat, vibration, and light. In this paper, we aim to eliminate or minimize the dependence of portable electronic devices to the batteries, which have limited life times, service costs, handling, and environmental problems. This is accomplished via incorporating the hybrid energy‐harvesting techniques and designed to power (bio)medical devices in order to measure vital signs. In this circuit, by simultaneously harvesting RF, light, thermal, and solar (natural and artificial) energies, we were able to increase the reliability of continuous supply of electrical energy in energy‐harvesting systems by generating and storing maximum power from the environment. Supercapacitors are used as the energy storage elements so that there is no energy waste, and each system is constantly storing the electrical energy with the aid of a diode block. In addition, with the help of supercapacitors, this device is able to transmit a maximum of 420 mW to the load and the total efficiency is equal to 74%.
Realization of synchronized modulations by stator flux trajectory tracking for low‐carrier‐ratio induction motor drives
Authors: Wu Xu , Xu Yingdong 
Published: April 2024

SummaryCompared with asynchronous voltage modulations, the synchronous space vector modulation (Syn‐SVPWM) can suppress current harmonics for high‐power induction motors (IM) by generating symmetrical voltage pulses. However, it is difficult to build a high‐performance current regulator based on Syn‐SVPWM because of the requirements of fixed voltage phases and the nonsymmetrical switching sequences in Syn‐SVPWM. Therefore, this manuscript proposes the equivalent realization of Syn‐SVPWM by the concept of stator flux trajectory tracking (SFTT). The new method controls the stator flux vector to move along evenly distributed flux samples in the complex plane. Then, the synchronization and symmetries of voltage pulses are maintained by organizing the switching sequence between adjacent flux samples. Meanwhile, the torque can be changed by online updating the control period based on the inverse torque model. Consequently, the proposed method can provide fast torque response with Syn‐SVPWM in a simple manner because it does not have to compensate the phase contradiction and to extract the fundamental of sampled current. Both simulations and experiments have verified the effectiveness of proposed method.
Metabolism of highly potent synthetic opioid nitazene analogs: N‐ethyl‐N‐(1‐glucuronyloxyethyl) metabolite formation and degradation to N‐desethyl metabolites during enzymatic hydrolysis
Authors: Kanamori Tatsuyuki , Okada Yuki , Segawa Hiroki , Yamamuro Tadashi , Kuwayama Kenji , Tsujikawa Kenji , Iwata Yuko T. 
Published: April 2024

AbstractThe metabolism of the highly potent synthetic opioids metonitazene, etonitazene, and protonitazene was investigated in fresh human hepatocytes. In the hydrolyzed culture medium, N‐desethyl‐, N,N‐di‐desethyl‐, O‐desalkyl‐, N‐desethyl‐O‐desalkyl‐, N,N‐di‐desethyl‐O‐desalkyl‐, and N‐oxidated metabolites were detected as phase I metabolites, whereas in the unhydrolyzed culture medium, O‐glucuronides of phase I metabolites with O‐dealkylation were detected as phase II metabolites. The detected phase I metabolites were identified by comparing their analytical data with those of synthesized authentic standards. In contrast, phase II metabolites were identified by comparing their analytical data with those of the glucuronidated products formed by the incubation of the corresponding substrates with human liver microsomes in the presence of uridine diphosphate glucuronic acid. In addition to the aforementioned metabolites, some putative N‐ethyl‐N‐(1‐glucuronyloxyethyl) metabolites were detected in the unhydrolyzed culture medium. Purification and hydrolysis experiments revealed that N‐ethyl‐N‐(1‐glucuronyloxyethyl) metabolites formed the corresponding N‐desethyl metabolites via unstable N‐ethyl‐N‐(1‐hydroxyethyl) metabolites during enzymatic hydrolysis.
The macroecology of butyrate‐producing bacteria via metagenomic assessment of butyrate production capacity
Authors: Brame Joel E. , Liddicoat Craig , Abbott Catherine A. , Edwards Robert A. , Robinson Jake M. , Gauthier Nicolas E. , Breed Martin F. 
Published: April 2024

AbstractButyrate‐producing bacteria are found in many outdoor ecosystems and host organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing the short‐chain fatty acid butyrate. However, the macroecological influences on their biogeographical distribution remain poorly resolved. Here we aimed to characterise their global distribution together with key explanatory climatic, geographical and physicochemical variables. We developed new normalised butyrate production capacity (BPC) indices derived from global metagenomic (n = 13,078) and Australia‐wide soil 16S rRNA (n = 1331) data, using Geographic Information System (GIS) and modelling techniques to detail their ecological and biogeographical associations. The highest median BPC scores were found in anoxic and fermentative environments, including the human (BPC = 2.99) and non‐human animal gut (BPC = 2.91), and in some plant–soil systems (BPC = 2.33). Within plant–soil systems, roots (BPC = 2.50) and rhizospheres (BPC = 2.34) had the highest median BPC scores. Among soil samples, geographical and climatic variables had the strongest overall effects on BPC scores (variable importance score range = 0.30–0.03), with human population density also making a notable contribution (variable importance score = 0.20). Higher BPC scores were in soils from seasonally productive sandy rangelands, temperate rural residential areas and sites with moderate‐to‐high soil iron concentrations. Abundances of butyrate‐producing bacteria in outdoor soils followed complex ecological patterns influenced by geography, climate, soil chemistry and hydrological fluctuations. These new macroecological insights further our understanding of the ecological patterns of outdoor butyrate‐producing bacteria, with implications for emerging microbially focused ecological and human health policies.
Gene expression, evolution, and the genetics of electrosensing in the smalltooth sawfish, Pristis pectinata
Authors: Jarva Taiya M. , Phillips Nicole M. , Von Eiff Cory , Poulakis Gregg R. , Naylor Gavin , Feldheim Kevin A. , Flynt Alex S. 
Published: April 2024

AbstractSawfishes (Pristidae) are large, highly threatened rays named for their tooth‐studded rostrum, which is used for prey sensing and capture. Of all five species, the smalltooth sawfish, Pristis pectinata, has experienced the greatest decline in range, currently found in only ~20% of its historic range. To better understand the genetic underpinnings of these taxonomically and morphologically unique animals, we collected transcriptomic data from several tissue types, mapped them to the recently completed reference genome, and contrasted the patterns observed with comparable data from other elasmobranchs. Evidence of positive selection was detected in 79 genes in P. pectinata, several of which are involved in growth factor/receptor tyrosine kinase signaling and body symmetry and may be related to the unique morphology of sawfishes. Changes in these genes may impact cellular responses to environmental conditions such as temperature, dissolved oxygen, and salinity. Data acquired also allow for examination of the molecular components of P. pectinata electrosensory systems, which are highly developed in sawfishes and have likely been influential in their evolutionary success.