bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soliton solutions of nonlinear stochastic Fitz-Hugh Nagumo equation
Authors: Iqbal Muhammad S. , Inc Mustafa , Yasin Muhammad W. , Ahmed Nauman , Tawfiq Ferdous M. , Bilal Muhammad , Baber Muhammad Z. , Rezapour Shahram 
Published: May 2024

AbstractThis study deals with the stochastic Fitz-Hugh Nagumo (FHN) equation and its multiple soliton solutions. The underlying model has numerous applications in neuroscience that express the pulse behavior of neurons. In general, different kinds of noise affect neurons, e.g., oscillations in the opening and closing of ion stations within cell membranes and the fluctuations of the different conductivities in the system. This fluctuation creates a sequence of stochastic excitation. Various applications are branching Brownian motion process, flame propagation, nuclear reactor theory, autocatalytic chemical reaction, mobility in neurons, population growth in the open environment, and liquid environment. So, need of the hour to consider the FHN equation under the impact of noise. The $$\phi ^6$$

ϕ
6

-model expansion method is used to extract the analytical solutions that give a dynamic attitude of the transmission for the nerve impulses of a nervous system. The different constraint conditions for the existence of these solutions are also discussed. The solutions of this model are represented in hyperbolic, trigonometric, and rational forms. The 2 and 3-dimensional behavior of these solutions are depicted by choosing the different values of parameters. The impact of noise on the physical system is analyzed and its real-world applications are discussed. The spikes in the solutions are controlled through the Borel function. These important results will open a new horizon of research for the young researchers.
The cybersecurity entrepreneur
Authors: Hodgins Mark W. 
Published: May 2024

AbstractCybersecurity is a major U.S. policy issue with a sizable coalition asserting that self-regulation is failing, primarily due to rampant low quality security products and a dearth of threat information sharing. State intervention proponents, however, generally disregard the role of cybersecurity entrepreneurial activity in fixing disequilibria. My research identifies how entrepreneurs adeptly satisfy consumers’ cybersecurity preferences by developing strong self-regulating mechanisms where data valuations are relatively high. I then empirically examine how entrepreneurial innovations have ameliorated discoordination and significantly improved market outcomes over time through the application of the market process and price theory.
Water Pricing and Quotas: A Quantitative Analysis from a Private and Social Perspective
Authors: Valle-García Ángela , Gutiérrez-Martín Carlos , Montilla-López Nazaret M. 
Published: May 2024

AbstractThe current situation of structural water scarcity due to the rise in demand, the reduction in supply as a consequence of climate change, increasingly frequent drought periods, and overall quantitative pressure on water resources creates a need for economic instruments to reduce the amount of water used, especially in the agricultural sector. Thus, water pricing and allocation quotas (proportional reduction of allocations) may be suitable tools to reduce demand or allocate scarce water resources. For a comparative analysis of the performance of these two measures, a Positive Mathematical Programming model has been developed, using the Guadalquivir River Basin as a case study. Additionally, the analysis takes into account the revenue generated from water pricing and the marginal cost of public funds. The results indicate that, from the farmer’s perspective, quotas result in smaller losses than water pricing. However, when considering water pricing along with the revenue generated from this measure, this mechanism would be more beneficial for society as a whole, since the taxes collected could be used for other purposes, albeit with efficiency losses measured by the marginal cost of public funds and the excess burden of taxation.
Urban Development and Climate Change: Implications for Educational Tourism Destination Planning
Authors: Rezapouraghdam Hamed , Hidalgo-García David 
Published: May 2024

AbstractGlobal warming caused by greenhouse gas emissions, transportation, and the transformation of land use caused by population growth is a critical problem that requires immediate and urgent interventions, especially in popular tourism destinations where the impact on quality of life is intense. In recent years, while new urban developments have been carried out for higher education institutions, less attention has been paid to the environmental implications of such expansions. Surprisingly, despite a growing interest in climate change action in educational institutions, little is known about the link between Land Surface Temperature (LST) variability and Surface Urban Heat Island (SUHI) of university campuses and their host communities. To fill the gaps mentioned earlier, this study aims to provide a comprehensive analysis of the spatial and temporal variability of the SUHI and the LST within a university campus and its surrounding urban environment. Using Sentinel 3 images and the TsHARP algorithm, the LST was determined, the SUHI was calculated, and the hot spots were obtained in an educational tourism hub; Famagusta, Cyprus. The Panel Data and ANOVA techniques were used for the subsequent analysis of the findings. Findings indicated that due to its low-rise buildings and large green areas, the studied campus not only had little contribution to the creation of SUHI but even minimized its effects on the urban areas attached to it. These findings provide valuable implications for authorities in standardizing criteria for future university establishments.
Secondary fracture prevention in Spanish primary care: results of the PREFRAOS Study
Authors: Martínez-Laguna Daniel , Carbonell Abella Cristina , Bastida José-Carlos , González Milagros , Micó-Pérez Rafael M. , Vargas Francisco , Díaz Torres Eva , Canals Laura ,   on behalf of the PREFRAOS Group
Published: May 2024

Abstract
Summary
This study demonstrated a large treatment gap in elderly subjects experiencing fragility fracture in Spanish primary care, a low treatment persistence among subjects who do receive treatment, and more than one-quarter having no follow-up visits post-fracture. These data highlight the need to improve secondary fracture prevention in primary care.

Purpose
To describe osteoporosis (OP) treatment patterns and follow-up in subjects with fragility fracture seen in Spanish primary care (PC).

Methods
This observational, retrospective chart review included subjects aged ≥ 70 years listed in the centers' records (November 2018 to March 2020), with ≥ 1 fragility fracture and prior consultation for any reason; subjects who had participated in another study were excluded. Outcomes included OP treatments and follow-up visits post-fragility fracture.

Results
Of 665 subjects included, most (87%) were women; overall mean (SD) age, 82 years. Fewer than two thirds (61%) had received any prior OP treatment (women, 65%; men, 38%); of these, 38% had received > 1 treatment (women, 25%; men, 13%). Among treated subjects, the most frequent first-line treatments were alendronate (43%) and RANKL inhibitor denosumab (22%), with a higher discontinuation rate and shorter treatment duration observed for alendronate (discontinuation, 42% vs 16%; median treatment duration, 2.5 vs 2.1 years). Over one-quarter (26%) of subjects had no follow-up visits post-fragility fracture, with this gap higher in women than men (35% versus 25%). The most common schedule of follow-up visits was yearly (43% of subjects with a fragility fracture), followed by half-yearly (17%) and biennial (10%), with a similar trend in men and women. Most OP treatments were prescribed by PC physicians, other than teriparatide and zoledronate.

Conclusions
Across Spanish PC, we observed a large gap in the treatment and follow-up of elderly subjects experiencing a fragility fracture. Our data highlights the urgent need to improve secondary fracture prevention in PC.
Variation in amylose content in three rice variants predominantly influences the properties of sushi rice
Authors: Hebishy Essam , Buchanan Dominic , Rice Julie , Oyeyinka Samson A. 
Published: May 2024

AbstractSushi rice is a ready-to-eat traditional Japanese dish seasoned with vinegar, sugar and salt that has gained popularity worldwide. There are many rice cultivars grown in the world which vary in their cooking, sensory, and processing quality. The aim of this study was to analyse chemical, physical, and functional properties of three rice varieties (Vietnamese, Italian, and Australian) to determine their suitability for sushi rice production. Rice was cooked using industry norms and vinegar was then added; samples with no vinegar were prepared for comparison. The rice was stored during 5 days at 4 °C after cooking for texture profile analysis and samples were taken on day 1 and day 5. Flour composition as well as amylose content, gelatinisation properties using differential scanning calorimeter, pasting properties using Rapid Visco Analyser, water absorption capacity (WAC), oil absorption capacity (OAC) and swelling power of extracted starch were determined. Results showed that the amylose content (16.51 to 21.37%) had a large impact on the functional and quality characteristics of the rice variants including texture, pasting, gelatinisation and WAC properties. Australian starch showed the highest amylose content, setback viscosity, final viscosity, pasting temperature and lowest gelatinisation temperature. The lower amylose content and gelatinisation temperature contributed to a softer texture in the Vietnamese rice samples over life. The added vinegar aided in keeping the texture soft during the shelf-life of the rice. Since sushi rice is usually prepared with vinegar, Italian and Vietnamese rice are better candidates for sushi rice based on their lower hardness after 5 days of storage when compared to the Australian variety.
Essential oils combat Botrytis cinerea in apples: unveiling sugar, vitamin, and antioxidant dynamics
Authors: Karakus Sinem , Atıcı Okkes , Turan Metin , Kaya Ozkan 
Published: May 2024

AbstractThis study investigated the effects of individual and combination applications of EOCs against Botrytis Cinerea in apple fruits, with a focus on sugar, vitamin, and antioxidant enzyme dynamics. In protective and curative treatments, sucrose content varied between 18.9 and 87.9 g.L-1, with the “CT” group exhibiting significantly higher sucrose levels (87.9 g.L-1). Glucose content ranged from 6.2 g.L-1 (“CT” and “C + F”) to 35.5 g.L-1 (“T + C + E + F”). Fructose content varied significantly, with the “F + T + C + E” treatment showing the highest (11.4 g.L-1) and the “CT” group the lowest (2.5 g.L-1). Rhamnose content in the curative treatment reached 14.9 g.L-1 (“F + T”) and in the protective treatment, the “C + E + F” group had the highest (3.3 g.L-1). Galactose content ranged from 0.1 to 13.0 g.L-1. Xylose content in curative treatment ranged from 12.1 to 13.6 g.L-1, with the combination “F + T” displaying the highest. In preventive treatment, arabinose content ranged from 0.7 to 3.0 g.L-1, with the “T + C + F” group having the highest. In terms of vitamins, the combination “T + F” showed the highest B1 (25.4 mg.100 g-1) and B2 (24.6 mg.100 g-1) content. Vitamin A, B1, and B2 increased in the “F + T” group, and vitamin C increased in the “F + T + C” group (33.4 mg.100 g-1). The quantification of oxidative stress markers and antioxidant enzymes revealed significant reductions in H2O2, MDA, and proline levels in EOC applications. In preventive treatment, the combination “T + C + E + F” exhibited the most effective improvement in SOD activity (556.5 EU mg-1 ), CAT activity increased significantly in the “T + C + F” group (189.3 EU mg-1), and APX activity saw the highest increase in the “T + C + E + F” group (185.6 EU mg-1). Contrastingly, curative treatments showed higher H2O2, MDA, and proline levels. The most significant decrease in H2O2 level occurred in the “T + C + E + F” group (36.7 nmol.g-1), and a significant decrease in MDA level was noted in the same group. Notable changes were observed in the activities of antioxidant enzymes, with the “F + T + C + E” group displaying the highest SOD activity (440.7 EU mg-1), and the “F + T” group showing the highest GST activity (542.0 EU mg-1). This research provided comprehensive insights into the biochemical responses of apple fruits to EOC treatments, offering potential strategies for effective fungal management in agriculture.
Effects of Process Conditions on Drying of Tomato Pomace in a Novel Daylight Simulated Photovoltaic-Assisted Drying System
Authors: Bayana Damla , İçier Filiz 
Published: May 2024

AbstractThe tomato pomace (TP), which is a by-product of the production of tomato paste, was dried in a novel custom-designed daylight simulated photovoltaic assisted dryer (DPVD). The different light applications (daylight, UV light, daylight + UV light, and without light), different air velocities (1.5 and 2 m/s), and different heating source modes (hot air and infrared) were applied to dry TP having a moisture content of 80.60 ± 0.73% to the moisture content of 7.66 ± 1.72%. The average water activity values of all dried samples were measured as 0.52 ± 0.08. Analysis was conducted to compare sun drying with the effects of process conditions on the quality (color properties, lycopene, β-carotene, and total mesophilic aerobic bacteria count) and performance (energy efficiency, exergy efficiency, specific moisture evaporation rate, and improvement potential) characteristics of TP. The effects of process conditions for each heating source mode were determined separately, and the improvement of the system performance for each mode was investigated. The effect of the process conditions on total aerobic mesophilic bacteria (TAMB) count was similar in general. In the infrared heating mode, the loss in lycopene and β-carotene contents was 59.55 ± 2.22 and 57.87 ± 2.51 minimum for 1.5 m/s air velocity without light application and for 2 m/s with ultraviolet + daylight application. In general, the performance of the system decreased in case of using ultraviolet light. The retention in the lycopene and β-carotene contents was higher in the infrared mode with light applications compared to hot air mode without light. The optimum drying conditions were air velocity of 2 m/s with “daylight” assistance in the hot air heating mode and with “ultraviolet + daylight” assistance in the infrared heating mode. All the energy and the daylight source used in drying applications were obtained from the sun, a renewable energy source, thanks to the photovoltaic panel and the solar tube units in the novel custom-designed drying system.
Microelements, Fatty Acid Profile, and Selected Biomarkers in Grass Carp (Ctenopharyngodon idella) Muscle Tissue: Seasonal Variations and Health Risk Assessment
Authors: Kovacik Anton , Helczman Marek , Arvay Julius , Tomka Marian , Snirc Marek , Janco Ivona , Fik Martin , Stefunkova Nikola , Dupak Rudolf , Harangozo Lubos , Tokarova Katarina , Kovacikova Eva , Jambor Tomas , Andreji Jaroslav , Massanyi Peter 
Published: May 2024

Abstract
The study assesses associations between microelement levels, fatty acid composition, and oxidative stress markers in grass carp muscle in the summer and autumn seasons. Additionally, various factors were considered, including the estimated daily intake (EDI), target hazard quotient (THQ), total THQ (TTHQ), and metal pollution index (MPI), to evaluate potential health risks for consumers. The microelements (Al, As, Ba, Cd, Co, Cr, Cu, Fe, Hg, Li, Mn, Ni, Pb, Se, Sr, and Zn) were determined using inductively coupled plasma optical emission spectrometry (ICP-OES), and total mercury was determined using cold-vapor atomic absorption spectroscopy (CV-AAS). Fatty acid profiling was realized using gas chromatography (GC) detection with a flame ionization detector (FID). The overall tendency of microelement levels was as follows: Fe > Zn > Al > Sr > Ba > Ni > Se > Cr> Cu > Mn > Pb > As > Li > Hg; <LOQ (below limit of quantification): Cd, and Co. The correlation analysis between concentrations of trace elements (Al, Ba, Cr, Cu, Mn, Li, Sr, Zn, and Hg) and the fatty acids (C16:0, C16:1, C18:1n9c, C18:2n6c, C20:4n6c, EPA, and DHA), as well as between Al, Ba, Fe, or Hg and oxidative stress markers (superoxide dismutase—SOD, glutathione peroxidase—GPx, or total antioxidant status—TAS), revealed statistically significant interactions in different seasons. THQ values were lower than 1; TTHQ values ranged from 0.27 to 0.76. The main toxic elements forming TTHQ were Hg and Ni (49%). The calculated health risk assessment indices indicate a low concentration of observed elements and low risks associated with the consumption of grass carp muscle from the tested location, although concentrations and THQ of mercury and nickel may be of slight concern.
C9orf72-Associated Dipeptide Repeat Expansions Perturb ER-Golgi Vesicular Trafficking, Inducing Golgi Fragmentation and ER Stress, in ALS/FTD
Authors: Sultana Jessica , Ragagnin Audrey M. G. , Parakh Sonam , Saravanabavan Sayanthooran , Soo Kai Ying , Vidal Marta , Jagaraj Cyril Jones , Ding Kunjie , Wu Sharlynn , Shadfar Sina , Don Emily K. , Deva Anand , Nicholson Garth , Rowe Dominic B. , Blair Ian , Yang Shu , Atkin Julie D. 
Published: May 2024

AbstractHexanucleotide repeat expansions (HREs) in the chromosome 9 open reading frame 72 (C9orf72) gene are the most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Both are debilitating neurodegenerative conditions affecting either motor neurons (ALS) in the brain and spinal cord or neurons in the frontal and/or temporal cortical lobes (FTD). HREs undergo repeat-associated non-ATG (RAN) translation on both sense and anti-sense strands, generating five distinct dipeptide repeat proteins (DPRs), poly-GA, -GR, -GP, -PA and -PR. Perturbed proteostasis is well-recognised in ALS pathogenesis, including processes affecting the endoplasmic reticulum (ER) and Golgi compartments. However, these mechanisms have not been well characterised for C9orf72-mediated ALS/FTD. In this study we demonstrate that C9orf72 DPRs polyGA, polyGR and polyGP (× 40 repeats) disrupt secretory protein transport from the ER to the Golgi apparatus in neuronal cells. Consistent with this finding, these DPRs also induce fragmentation of the Golgi apparatus, activate ER stress, and inhibit the formation of the omegasome, the precursor of the autophagosome that originates from ER membranes. We also demonstrate Golgi fragmentation in cells undergoing RAN translation that express polyGP. Furthermore, dysregulated ER-Golgi transport was confirmed in C9orf72 patient dermal fibroblasts. Evidence of aberrant ER-derived vesicles in spinal cord motor neurons from C9orf72 ALS patients compared to controls was also obtained. These data thus confirm that ER proteostasis and ER-Golgi transport is perturbed in C9orf72-ALS in the absence of protein over-expression. Hence this study identifies novel molecular mechanisms associated with the ER and Golgi compartments induced by the C9orf72 HRE.
The bubble theory: exploring the transition from first replicators to cells and viruses in a landscape-based scenario
Authors: Piast Radoslaw W. 
Published: May 2024

AbstractThis study proposes a landscape-based scenario for the origin of viruses and cells, focusing on the adaptability of preexisting replicons from the RNP (ribonucleoprotein) world. The scenario postulates that life emerged in a subterranean “warm little pond” where organic matter accumulated, resulting in a prebiotic soup rich in nucleotides, amino acids, and lipids, which served as nutrients for the first self-replicating entities. Over time, the RNA world, followed by the RNP world, came into existence. Replicators/replicons, along with the nutritious soup from the pond, were washed out into the river and diluted. Lipid bubbles, enclosing organic matter, provided the last suitable environment for replicons to replicate. Two survival strategies emerged under these conditions: cell-like structures that obtained nutrients by merging with new bubbles, and virus-like entities that developed various techniques to transmit themselves to fresh bubbles. The presented hypothesis provides the possibility for the common origin of cells and viruses on rocky worlds hosting liquid water, like Earth.
The relationship between parenting style and the stigma of mental illness in adolescent athletes: the chain mediating role of self-esteem and mental toughness
Authors: Xiang Jun , Gao Jia , Gao Yun 
Published: May 2024

AbstractThe stigma surrounding mental illness is pervasive among athletes competing at the highest levels, and the adolescent athlete’s parenting style, self-esteem, and mental toughness are intimately linked to this stigma. These factors are particularly influential in determining the future career trajectory and athletic pursuits of young athletes. The objective of this study is to examine the correlation between parenting style and the stigma of mental toughness in adolescent athletes, while also confirming the intermediary influence of self-esteem and mental toughness in the relationship between the two variables. A survey was initiated on randomly selected 386 athletes at or above Level I in Guangdong Province through standardized questionnaires based on a parenting assessment scale, self-stigma scale, self-esteem scale, and mental toughness scale. The analysis and experimentation show that parenting style has a significant negative predictive impact on the self-esteem, mental toughness, and mental illness stigma of adolescent athletes. The impact of age and gender on the above factors are also explored. Furthermore, parenting style was also found to indirectly predict mental illness stigma through a chain mediation effect of self-esteem and mental toughness. These results highlight the importance of considering parenting style in improving the self-esteem and mental toughness of adolescent athletes, with the ultimate goal of reducing the stigma of mental illness among this population.
Who gets duped? The impact of education on fraud detection in an investment task
Authors: Blackwell Calvin , Maynard Norman , Malm James , Pyles Mark , Snyder Marcia , Witte Mark 
Published: May 2024

AbstractMany financial scandals appear to depend on a lack of skepticism on the part of their victims. Sophisticated investors trusted Bernie Madoff, for example, despite early warning signs of implausible returns. Our study investigates how education explains fraud detection in financial decision-making. In a simple survey, economics and finance students are asked to make an investment recommendation from among four hypothetical funds, including one based on Madoff’s fund. We use Truth Default Theory to explain our results. We show that education increases the likelihood that students are suspicious of Madoff’s fund, and that for students whose suspicions are aroused, education makes them less likely to choose the Madoff fund.
Hardy–Sobolev–Rellich, Hardy–Littlewood–Sobolev and Caffarelli–Kohn–Nirenberg Inequalities on General Lie Groups
Authors: Ruzhansky Michael , Yessirkegenov Nurgissa 
Published: May 2024

AbstractIn this paper, we establish a number of geometrical inequalities such as Hardy, Sobolev, Rellich, Hardy–Littlewood–Sobolev, Caffarelli–Kohn–Nirenberg, Gagliardo-Nirenberg inequalities and their critical versions for an ample class of sub-elliptic differential operators on general connected Lie groups, which include both unimodular and non-unimodular cases in compact and noncompact settings. We also obtain the corresponding uncertainty type principles.