bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanoparticles and cars - analysis of potential sources
Authors: Uibel Stefanie , Takemura Masaya , Mueller Daniel , Quarcoo David , Klingelhoefer Doris , Groneberg David A 
Published: July 2012

Abstract
Urban health is potentially affected by particle emissions. The potential toxicity of nanoparticles is heavily debated and there is an enormous global increase in research activity in this field. In this respect, it is commonly accepted that nanoparticles may also be generated in processes occurring while driving vehicles. So far, a variety of studies addressed traffic-related particulate matter emissions, but only few studies focused on potential nanoparticles.
Therefore, the present study analyzed the literature with regard to nanoparticles and cars. It can be stated that, to date, only a limited amount of research has been conducted in this area and more studies are needed to 1) address kind and sources of nanoparticles within automobiles and to 2) analyse whether there are health effects caused by these nanoparticles.
Current state of the art in laparoscopic colorectal surgery for cancer: Update on the multi-centric international trials
Authors: Lee Jennifer K , Delaney Conor P , Lipman Jeremy M 
Published: July 2012

Abstract
Laparoscopic colectomy is now widely applied to cases of malignancy, supported by early data from several large randomized controlled trials. Long-term follow-up is now available from those trials, supporting equivalency of cancer-free and overall survival for open and laparoscopic resections. This promising data has inspired further exploration of other applications of laparoscopic techniques, including use of single incision laparoscopy. This article reviews recent reports of long-term data for colorectal cancer resection from four randomized, prospective international trials.
Neurological status in paediatric upper limb injuries in the emergency department – current practice
Authors: Robertson James S , Marsh Andrew G , Huntley James S 
Published: July 2012

Abstract

Background
In upper limb injuries it is important to assess associated neurological injury. The aim of this study was to assess the initial (Emergency Department (ED)) documentation of neurological status in paediatric patients presenting with upper limb injuries.

Findings
Case notes of paediatric patients admitted to the orthopaedic ward with upper limb injuries were retrospectively collected over a three month period. Initial ED documentation was recorded and case notes examined for any neurological deficit on admission. Of the 121 patients, 107 (88.4%) of case notes had some form of neurological documentation. The remaining case notes (n = 14, 11.6%) had no mention of neurological examination. There were 10 (8.2%) patients with pre-operative neurological deficits identified; none of these had been previously identified by the ED.

Conclusion
There are failings of neurological documentation on the part of ED staff. It is likely that these reflect a knowledge deficit in the examination of the injured upper limb in paediatric patients.
A case series of low dose bevacizumab and chemotherapy in heavily pretreated patients with epithelial ovarian cancer
Authors: Defferrari Carlotta , Campora Sara , D'Amico Mauro , Piccardo Arnoldo , Biscaldi Ennio , Rosselli Daniela , Pasa Ambra , Puntoni Matteo , Gozza Alberto , Gennari Alessandra , Zanardi Silvia , Lionetto Rita , Bandelloni Michela , DeCensi Andrea 
Published: July 2012

Abstract

Background
The addition of bevacizumab to standard chemotherapy prolongs progression free survival in the first line treatment of epithelial ovarian cancer (EOC), but its cost/effectiveness is debated. We assessed the safety and activity of a lower dose of bevacizumab in pretreated advanced stage EOC.

Methods
We treated 15 patients, mostly with platinum resistant EOC, who had received a median of four prior cytotoxic regimens, with bevacizumab 5–7.5 mg/kg q21 days in combination with either carboplatin (n = 8), oral cyclofosfamide (n = 5) or weekly paclitaxel (n = 2). Bevacizumab was administered until disease progression. Tumor response was assessed by CA125 and fusion 18 F-FDG PET/contrast enhanced CT.

Results
The median number of bevacizumab cycles was 21 (range 3–59). The median baseline CA125 was 272 U/ml and decreased to 15.2 U/ml at nadir. Tumor response was 4 complete response (CR) (26.7%) and 7 partial response (PR) (46.7%) by chemotherapy (CT), with an overall response rate of 73.4% (95% CI, 51.0 – 95.8) according to Response Evaluation Criteria In Solid Tumors (RECIST), and 6 CR (40%) and 4 PR (26.7%) by PET, for an overall metabolic response rate of 67% (95%CI, 42.8 – 90.6) according to PET Response Criteria in Solid Tumors (PERCIST). Median progression free survival (PFS) was 21 months and median overall survival (OS) was 24 months. Grade 3 adverse events related to bevacizumab were hypertension (n = 2), proteinuria (n = 1) and epistaxis (n = 5). Treatment was delayed in five patients for nasal bleeding or uncontrolled hypertension.

Conclusions
Low-dose bevacizumab and chemotherapy was well tolerated and active in a heavily pretreated population of advanced EOC. Further studies should assess the activity of low dose bevacizumab in EOC.
Towards a “4I” approach to personalized healthcare
Authors: Payne Philip R O , Marsh Clay B 
Published: July 2012

AbstractPersonalized healthcare holds the promise of ensuring that every patient receives optimal wellness promotion and clinical care based upon his or her unique and multi‐factorial phenotype, informed by the most up‐to‐date and contextually relevant science. However, achieving this vision requires the management, analysis, and delivery of complex data, information, and knowledge. While there are well‐established frameworks that serve to inform the pursuit of basic science, clinical, and translational research in support of the operationalization of the personalized healthcare paradigm, equivalent constructs that may enable biomedical informatics innovation and practice aligned with such objectives are noticeably sparse. In response to this gap in knowledge, we propose such a framework for the advancement of biomedical informatics in order to address the fundamental information needs of the personalized healthcare domain. This framework, which we refer to as a “4I” approach, emphasizes the pursuit of research and practice that is information‐centric, integrative, interactive, and innovative.
Reflections on the Faculty of General Dental Practice (UK) at 20 years
Authors: Scott Julian , Lowndes Peter , Farrell Shelagh , Santini Ario 
Published: July 2012

This paper presents the reflections of four colleagues who were instrumental in the foundation of the then Faculty of General Dental Practitioners (UK) in 1992. All four subsequently became members of the first Board of Faculty, of whom one became the second Dean of the Faculty and one became the first editor of Primary Dental Care. Two are members of the current Board. They were asked to reflect on six questions, which were: 1. What were the original hopes at the inception of the Faculty 20 years ago? 2. Have these hopes and expectations that you had 20 years ago been realised? 3. If the original aspirations have been met, what factors made this possible? 4. If some aspirations have not been realised, why? 5. What trends will shape dentistry in the next 20 years? 6. Where would you like to see the Faculty in 20 years’ time?
Radioactive decay data: powerful aids in medical diagnosis and therapy, analytical science and other applications
Authors: Nichols A. L. 
Published: July 2012

Abstract
Decay data are commonly used to characterise and quantify radioactive material, and provide an important means of understanding the properties and structure of the nucleus. Experimental measurement techniques are reviewed, with the emphasis placed on recent developments that represent a potential quantum leap in advancing our knowledge, particularly by means of γ-ray spectroscopy. A select number of internationally-accepted decay-data evaluations and compilations are also discussed in terms of their contents. Both energy and non-energy related applications require the input of well-defined decay data, and such activities have been reviewed. Various important decay-data issues are assessed, and note taken of any significant requirements for better quantified data.
Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions
Authors: Carroll V. , Demoin D.W. , Hoffman T.J. , Jurisson S.S. 
Published: July 2012

AbstractRadiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This field of radiochemistry is multidisciplinary, involving radiometal production, separation of the radiometal from its target, chelate design for complexing the radiometal in a biologically stable environment, specific targeting of the radiometal to its in vivo site, and nuclear imaging and/or radiotherapy applications of the resultant radiopharmaceutical. The critical importance of inorganic chemistry in the design and application of radiometal-containing imaging and therapy agents is described from a historical perspective to future directions.
Chemistry of superheavy elements
Authors: Schädel M. 
Published: July 2012

AbstractThe chemistry of superheavy elements - or transactinides from their position in the Periodic Table - is summarized. After giving an overview over historical developments, nuclear aspects about synthesis of neutron-rich isotopes of these elements, produced in hot-fusion reactions, and their nuclear decay properties are briefly mentioned. Specific requirements to cope with the one-atom-at-a-time situation in automated chemical separations and recent developments in aqueous-phase and gas-phase chemistry are presented. Exciting, current developments, first applications, and future prospects of chemical separations behind physical recoil separators (“pre-separator”) are discussed in detail. The status of our current knowledge about the chemistry of rutherfordium (Rf, element 104), dubnium (Db, element 105), seaborgium (Sg, element 106), bohrium (Bh, element 107), hassium (Hs, element 108), copernicium (Cn, element 112), and element 114 is discussed from an experimental point of view. Recent results are emphasized and compared with empirical extrapolations and with fully-relativistic theoretical calculations, especially also under the aspect of the architecture of the Periodic Table.
The present and future of medical radionuclide production
Authors: Qaim S. M. 
Published: July 2012

AbstractMedical radionuclide production technology is well established. Both reactors and cyclotrons are utilized for production; the positron emitters, however, are produced exclusively using cyclotrons. A brief survey of the production methods of most commonly used diagnostic and therapeutic radionuclides is given. The emerging radionuclides are considered in more detail. They comprise novel positron emitters and therapeutic radionuclides emitting low-range electrons and α-particles. The possible alternative production routes of a few established radionuclides, like68Ga and99mTc, are discussed. The status of standardisation of production data of the commonly used as well as of some emerging radionuclides is briefly mentioned. Some notions on anticipated future trends in the production and application of radionuclides are considered.
Adsorption of tetravalent thorium by geomedia
Authors: Melson Nathan H. , Haliena Brian P. , Kaplan Daniel I. , Barnett Mark O. 
Published: July 2012

AbstractWe measured the pH-dependent adsorption of Th(IV), an analogue for Pu(IV) and other tetravalent actinides, to two geomedia: goethite (α-FeOOH(s)) and a heterogeneous Fe-containing sand from the southeastern USA. The goal was to examine whether or not the Th(IV)-goethite adsorption data could be used to predict the adsorption of Th(IV) by the heterogeneous sand. In the absence of either geomedia, after forty-eight hours the measured pH-dependent “adsorption” was consistent with the solubility of solid amorphous ThO2(am, aged), despite the fact that ThO2(am, aged) is generally not formed until approximately seventy days. We concluded that ThO2(am, aged) was stabilized by precipitating on the walls of the reaction vessels. Ignoring this phenomenon could lead to experimental artifacts in Th(IV) adsorption studies. Thorium adsorption by both goethite and the sand was strongly pH dependent, with adsorption increasing sharply from pH ∼ 2 to pH ∼ 4. Two methods were utilized to predict the pH-dependent adsorption of Th(IV) by the sand using the Th(IV)-goethite adsorption data. Using the Fe content of the sand and the Th(IV)-goethite adsorption data, we were able to predict the maximum amount of Th(IV) adsorption by the sand within 78% of the actual value (i.e., an error of 22%). In contrast, on a surface-area-normalized basis, we were only able to predict the maximum adsorption of Th(IV) by the sand within a factor of two. These results have important implications to scaling and extrapolating the results of batch-scale tetravalent actinide adsorption studies with pure minerals to predict their field-scale adsorption by and transport in heterogeneous subsurface media.
A Comparative Study on the Activation Behavior of Implanted Boron and Phosphorus for LTPS Using Solid-Phase Crystallization
Authors: Li Qinglong , Mudgal Tarun , Meller Patricia M. , Slavin Seth , Manley Robert G. , Hirschman Karl D. 
Published: July 2012

ABSTRACTThis work presents a study on the activation behavior of high-dose (φ > 1015 cm-2) boron and phosphorus implants for low resistance source and drain regions for thin-film transistors (TFTs) fabricated using solid-phase crystallization (SPC) of amorphous silicon. Process variables include factors associated with ion implant and annealing conditions, as well as the SPC and implant process arrangement. Four-point probe sheet resistance (Rs) measurements were used as a comprehensive assessment of the electrical properties. Results have identified similarities and differences in activation behavior that can influence process integration strategies considering both the SPC approach and TFT fabrication.
Plasma Etching of Copper Thin Film over a Dielectric Step and Electromigration Failure Mechanism
Authors: Lin Chi-Chou , Kuo Yue 
Published: July 2012

ABSTRACTProcess and electromigration issues of the copper line over a dielectric step etched with a new plasma-based process have been studied. The N2 and CF4 additive gas effects on the line profile, undercut, and “neck” formation at the cusp area were investigated with respect to changes of the plasma phase chemistry and ion bombardment energy. The sidewall passivation layer hindered the excessive attack of the cusp region. The undercut of the photoresist pattern caused the residue formation. The lifetime of the etched copper was related to the line shape and the film topography, which directly affected the local current density and stress. With the proper control the plasma phase chemistry and ion bombardment energy, the Cu film over a topographic surface can be etched into fine lines with a long electromigration lifetime.
RE dependence of superconductivity in parent T’-RE2CuO4 – implication on the nature of superconductivity
Authors: Naito Michio , Ikeda Ai , Yamamoto Hideki , Manabe Takaaki 
Published: July 2012

ABSTRACTWe present the results of our systematic investigation of the RE dependency of superconductivity in the parent compounds T’-RE2CuO4 (RE = Pr, Nd, Sm, Eu, Gd, and Tb). Superconducting samples were prepared by metal organic decomposition (MOD). A stringent control of synthesis- and post-annealing-conditions is required to obtain superconducting samples. Superconductivity with a transition temperature (Tconset) ≥ 30 K is achieved for RE = Pr and Nd. By contrast, Tconset is at highest 20 K for RE = Gd. Our results indicate that the induction of superconductivity into T’-RE2CuO4 cuprates strongly depends on the RE3+ ionic size. This trend is discussed from the viewpoint of RE-dependent thermodynamic stability of T’-RE2CuO4. For smaller RE3+ ions, the thermodynamic boundary conditions become tighter.
Thermoelectric Power Measurement of Catalyst-free Si-doped GaAs Nanowires
Authors: Yamaguchi Masahito , Paek Jihyun , Amano Hiroshi 
Published: July 2012

ABSTRACTSi-doped GaAs nanowires (NWs) were grown on (111)Si substrate by MBE-VLS method. The electrical characteristics of the GaAs NWs were measured. A joule heater was arranged near the tip of NW for making the gradient of substrate temperature. The obtained Seebeck coefficient of the GaAs NW increases linearly with a rise in temperature. The thermoelectric power of the Si doped GaAs NW was determined by the hole diffusion. It was estimated that the hole density in the Si-doped GaAs NW at room temperature was 5.9×1018 cm-3 from the slope of the temperature dependence of the Seebeck coefficient in the Si-doped GaAs NW. At room temperature, the Seebeck coefficient, thermoelectric power factor, and thermoelectric figure of merit (ZT) were 429 μV/K, 271μW/mK2, and 1.5×10-3, respectively.
Stress-induced Bimodal Ordering in POSS/PCL Biodegradable Shape Memory Nanocomposites
Authors: Alvarado-Tenorio Bonifacio , Romo-Uribe Angel , Mather Patrick T. 
Published: July 2012

ABSTRACTSimultaneous wide- and small- angle X-ray scattering (WAXS-SAXS) has revealed a stress-induced bimodal orientation of POSS crystals and PCL chains, both in a constrained POSS/PCL crosslinked network architecture with shape memory properties. POSS/PCL nanocomposites with molecular weight of 2,600 g/mol exhibiting shape memory behavior were synthesized and variation of crosslinker molar ratio was used to obtain POSS/PCL networks with different crosslink density (Alvarado-Tenorio et al., Macromolecules, 44, 5682, 2011). In that study it was shown that there are POSS crystals embedded in an amorphous PCL matrix, and the POSS crystals were ordered in a cubic nanostructure. In this work, it will be shown that elongation at room temperature of all the networks yielded a double-induced orientation (90º and 180º) of the POSS crystals, as indicated by the 101 reflection. Moreover, it was also detected stretched-induced crystallization of the otherwise amorphous PCL chains. Furthermore, SAXS data showed long periods in the meridional and equatorial orientations of 630 Å, 90 Å and 45 Å corresponding to a lamellar nanostructure of PCL chains. The induced bimodal orientation of the POSS-PCL molecular network will be correlated with its shape memory properties.
Synthesis of Three Dimensional Carbon Nanostructure Foams for Supercapacitors
Authors: Wang Wei , Guo Shirui , Ruiz Isaac , Ozkan Mihrimah , Ozkan Cengiz S. 
Published: July 2012

ABSTRACTIn this work, we demonstrated the growth of three dimensional graphene/carbon nanotubes hybrid carbon nanostructures on metal foam through a one-step chemical vapor deposition (CVD). The as-grown three dimensional carbon nanostructure foams can be potentially used as the electrodes of energy storage devices such as supercapacitors and batteries. During the CVD process, the carbon nanostructures are grown on highly porous nickel foam to form a high surface area 3-D carbon nanostructure by introducing a mixture precursor gases (H2, C2H2). The surface morphology was investigated by scanning electron microscopy (SEM) and the results demonstrated relatively homogeneous and densely packed 3-D carbon nanostructure. The quality was characterized by Raman spectroscopy. To further increase the capacitive capability the supercapacitors were fabricated based on the electrodes of carbon nanostructure foam and cyclic voltammetry, charge-discharge, and electrochemical impedance spectroscopy (EIS) were conducted to determine their performance.
Role of Gas-phase Reactions and Thermal Gradient Control in Carbon Nanotube Synthesis
Authors: Youn Seul Ki , Gopi Baskar Pagadala , Teo Kenneth B. K. , Park Hyung Gyu 
Published: July 2012

ABSTRACTWe investigate the role of precursor thermal rearrangement and surface catalytic reactions in the synthesis of vertically aligned carbon nanotubes (VA-CNTs) by acetylene-based, chemical vapor deposition (CVD) and demonstrate a millimeter-long growth of single-walled CNT (SWNT) without water assistance. A substrate heater was used to create an ascending temperature gradient from gas injection to catalyst substrate. Whereas temperature of catalyst substrates primarily determines their catalytic activity, it is a thermal condition of a gaseous mixture in the CVD chamber that also influence growth yield and structural features of as-grown CNTs. Employing Egloff’s characterization, [1] we discuss the importance of various gas thermal zones in producing high-quality nanotubes with augmented growth efficiency. We continue to report production of millimeter-long, VA-SWNT having a mean diameter of 1.7 ± 0.7 nm, catalyzed by iron on an alumina support. Important finding is that a million of aspect ratio of SWNT arrays can be produced, without water assistance, via combined action of an ascending temperature gradient toward catalyst substrate and low partial pressures of acetylene carbon feedstock. Our results do not only emphasize the role of precursor thermal rearrangement in CNT synthesis, but also offer a practical route to the modulation of such complex phenomena for an ultrahigh-yield growth of narrow VA-SWNT.
Large-area Metrology of CVD-grown Graphene Layers on Copper Foil Substrates
Authors: Pleskot Dennis L. , Kyle Jennifer R. , Ghazinejad Maziar , Guo Shirui , Ruiz Isaac , Ozkan Mihrimah , Ozkan Cengiz S. 
Published: July 2012

ABSTRACTFluorescence Quenching Microscopy has been shown to be an effective means of characterizing graphene on the macroscale. Centimeter-scale CVD-grown pristine and doped graphene were manufactured in a high temperature (1000°C) furnace on pristine copper substrates. The copper was then etched away in a FeCl3solution and the graphene was coated with DCM-based fluorescent dye before being imaged in a fluorescence microscope. The fluorescence image was then image-processed using modified Matlab software. The resulting image showed clear contrast between the pristine graphene sheet and defects on the graphene surface, which revealed that fluorescence microscopy could determine the quality of a large region of graphene. Also, significant contrast was identified between single-layer and multi-layer regions, showing that this technique is also effective at determining the degree of uniformity within a graphene sample. Lastly, the fluorescence images showed contrast between doped and undoped regions of graphene.
Generation of hydrogen peroxide on a pyridine-like nitrogen-nickel doped graphene surface
Authors: Rangel E. , Magana L. F. , Sansores L. E. , Vázquez G.J. 
Published: July 2012

ABSTRACTDensity functional theory and molecular dynamics were used to study the generation of hydrogen peroxide around a nickel atom anchored on a pyridine-like nitrogen-doped graphene (PNG) layer. First, we found that two hydrogen molecules are adsorbed around the nickel atom, with adsorption energy 0.95 eV/molecule. Then we studied the interaction of oxygen molecules with this system at atmospheric pressure and 300 K. It is found that two hydrogen peroxide molecules are formed. However, at 700 K, one hydrogen peroxide molecule, and one water molecule are desorbed. One oxygen atom stays bound to the nickel atom.
Growth of Carbon Nanotube Forests on Carbon Fibers with a SiO2 Interlayer
Authors: Antunes Erica F. , da Silva Viviane Q. , Marques Vagner E. C. , Siqueira Lilian , Corat Evaldo J. 
Published: July 2012

ABSTRACTCeramic barriers avoid catalyst diffusion to produce better multiwall carbon nanotubes (CNT) on carbon fiber fabrics (CF). We developed a simple method to produce efficiently a silica layer from TEOS pyrolysis at similar conditions of CNT growth from camphor and ferrocene mixtures. This protective layer prevents iron diffusion and allows the vertical alignment of CNTs.