bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lateral Transport Controls the Tidally Averaged Gravitationally Driven Estuarine Circulation: Tidal Mixing Effects
Authors: Kukulka Tobias , Chant Robert J. 
Published: April 2024

Abstract
In classic models of the tidally averaged gravitationally driven estuarine circulation, denser salty oceanic water moves up the estuary near the bottom, while less dense riverine water flows toward the ocean near the surface. Traditionally, it is assumed that the associated pressure gradient forces and salt advection are balanced by vertical mixing. This study, however, demonstrates that lateral (across the estuary width) transport processes are essential for maintaining the estuarine circulation. This is because for realistic estuarine bathymetry, the depth-integrated salt transport up the estuary is enhanced in the deeper estuary channel. A closed salt budget then requires the lateral transport of this excess salt in the deeper channel toward the estuarine flanks. To understand how such lateral transport affects the estuarine salt and momentum balances, we devise an idealized model with explicit lateral transport focusing on tidally averaged lateral mixing effects. Solutions for the along-estuary velocity and salinity are nondimensionalized to depend only on one single nondimensional parameter, referred to as the Fischer number, which describes the relative importance of lateral to vertical tidal mixing. For relatively strong lateral tidal mixing (greater Fischer number), salinity and velocity variations are predominantly vertical. For relatively weak lateral tidal mixing (smaller Fischer number), salinity and velocity variations are predominantly lateral. Overall, lateral transport greatly affects the estuarine circulation and controls the estuarine salinity intrusion length, which is demonstrated to scale inversely with the Fischer number.
Analysis and Prediction of Summer Rainfall over Southwestern Utah
Authors: Horel John D. , Powell James T. 
Published: April 2024

Abstract
While many studies have examined intense rainfall and flash flooding during the North American monsoon (NAM) in Arizona, Nevada, and New Mexico, less attention has focused on the NAM’s extension into southwestern Utah. This study relates flash flood reports and Multi-Radar Multi-Sensor (MRMS) precipitation across southwestern Utah to atmospheric moisture content and instability analyses and forecasts from the High-Resolution Rapid Refresh (HRRR) model during the 2021–23 monsoon seasons. MRMS quantitative precipitation estimates over southwestern Utah during the summer depend largely on the areal coverage from the KICX WSR-88D radar near Cedar City, Utah. Those estimates are generally consistent with the limited number of precipitation gauge reports in the region except at extended distances from the radar. A strong relationship is evident between days with widespread precipitation and afternoons with above-average precipitable water (PWAT) and convective available potential energy (CAPE) estimated from HRRR analyses across the region. Time-lagged ensembles of HRRR forecasts (initialization times from 0300 to 0600 UTC) that are 13–18 h prior to the afternoon period when convection is initiating (1800–2100 UTC) are useful for situational awareness of widespread precipitation events after adjusting for underprediction of afternoon CAPE. Improved skill is possible using random forest classification relying only on PWAT and CAPE to predict days experiencing excessive (upper quartile) precipitation. Such HRRR predictions may be useful for forecasters at the Salt Lake City National Weather Service Forecast Office to assist in issuing flash flood potential statements for visitors to national parks and other recreational areas in the region.

Significance Statement
Summer flash floods in southwestern Utah are a risk to area residents and millions of visitors annually to the region’s national parks, monuments, and recreational areas. The likelihood of flash floods within the region’s catchments depends on the intense afternoon and early evening convection initiated by lift and instability primarily due to terrain–flow interactions over elevated plateaus and mountains. Forecasts at lead times of 13–18 h of moisture and instability from the operational High-Resolution Rapid Refresh model have the potential to predict summer afternoons that are likely to have increased risks for higher rainfall amounts across southwestern Utah, although they are not expected to predict the likelihood of flash floods in any specific locale.
The Extent, Excessiveness and Sustainability of Afghanistan’s Current Account
Authors: Sultani Abdul Hadi , Faisal U. 
Published: April 2024

This article empirically investigates the extent, excessiveness and sustainability of Afghanistan’s current account (CA) deficits using quarterly data from 2004-Q2 to 2019-Q4. The framework of this article is the intertemporal approach to the CA using the present value model. First, a descriptive analysis of Afghanistan’s CA is conducted. Next, a bivariate vector auto-regressive (VAR) model is applied to estimate the optimal CA of the economy, which can be compared to the actual one to determine how excessiveness the actual CA is relative to the optimal one. The Augmented Dickey-Fuller and Johnson co-integration tests are applied to examine the necessary and sufficient conditions for the sustainability of the CA. Findings indicate that Afghanistan’s actual CA deficits are excessive and too variant relative to the optimal one; therefore, the deficit is considered problematic. The empirical results further disclose that Afghanistan’s CA is unsustainable. The lack of co-integration between real net output and real private consumption and between exports and imports suggests that the unsustainability is mainly due to the weakness of domestic production in satisfying internal demand and the failure of real export volume to equilibrate the trade balance. Hence, this study recommends increasing the level of domestic output, and reduction in imports supported by improvements in saving rate, infrastructure and export to improve the CA. JEL Codes: F14, F32, F39, C22
Does Female on Board Affect M&A Participating Firms’ Performance? Empirical Evidence from India Using Dynamic Panel Data Analysis
Authors: Kumar Sarika , Kapil Sheeba 
Published: April 2024

The aim of this research is to examine the impact of gender diversity and female leadership position on the firm performance of Indian listed firms participating in mergers and acquisitions (M&A) activities. Available research has focused on a small sample of firms and considered ‘gender diversity’ as the only variable. Bearing this in mind, this study focusses on the leadership positions females hold on corporate board along with gender diversity affecting the firm performance measures for the sample of M&A participating firms, as M&As lead to major restructuring of the board. The ‘gender diversity’ is measured with the number of females present on corporate board as directors, ‘leadership position’ is measured with females holding the position either as Chief Executive Officer (CEO) or Chairperson on the board. The study employs panel data set for Indian non-financial National Stock Exchange listed M&A participating firms for the period 2013–2020. Using a system of GMM dynamic panel estimates, the study analyses the relationship between gender diversity and females’ varied leadership position on the firm performance measures, that is, return on asset, Tobin’s q. The findings reveal that there is a positive association between gender diversity and firm performance measures. Females holding the top leadership positions as either CEO or Chairperson on the board positively impact the firm performance measures. This study adds to the existing literature on gender diversity at the board level and M&A literature in the Indian context. JEL Codes: G 3, G 34, J 16
Assessing the quality of life priorities in the elderly: Application of the Turkish-Adapted Mayers’ Lifestyle Questionnaire (3)
Authors: Özata Değerli Medine Nur , Altuntaş Onur , Bumin Gonca 
Published: April 2024

Introduction: The growing aging population requires the development of new policies and programs to meet the needs and expectations of the elderly. Identifying priorities for the elderly’s quality of life can be the foundation for rehabilitation services provided to the elderly. This study aims to assess the quality of life priorities in the elderly using the Turkish-adapted Mayers’ Lifestyle Questionnaire (3). Method: The study included 171 elderly with a mean age of 74.72 ± 4.36 years. Participants completed a sociodemographic information form and the Turkish-Adapted Mayers’ Lifestyle Questionnaire (3). Results: Quality of life priorities for elderly people were independence in reading and writing, participation in paid and/or voluntary work, spiritual, and satisfying activities, and the ability to make choices about their lives. Conclusion: The study results showed that Mayers’ Lifestyle Questionnaire (3) supports setting priorities by examining the quality of life of elderly people from a multidimensional perspective. The use of Mayers’ Lifestyle Questionnaire (3) can contribute to the development of effective strategies aimed at improving the quality of life for elderly individuals. A holistic approach to each factor affecting quality of life will enable occupational therapists and other professionals involved with elderly people to consider person-centered factors in their interventions.
Assessing safety and feasibility of monopolar transurethral resection of the prostate without post-operative catheter traction: A randomized controlled trial
Authors: KP Abhineeth , Madhavan Kumar , Kaushal Devashish , Biswas Manoj , Plash Sonu Kumar , MR Viswas 
Published: April 2024

Introduction: Traction on the per-urethral catheter is commonly employed after monopolar transurethral resection of the prostate (mTURP) to reduce bleeding. However, its efficacy and impact on postoperative pain remain uncertain. Further, there is limited evidence to suggest any benefit regarding post-operative blood loss. Materials and methods: In a randomized controlled trial, 62 patients undergoing mTURP were assigned to either a traction ( n = 30) or non-traction ( n = 32) group. Blood loss, postoperative pain, and analgesic requirements were assessed between January 2022 and April 2023. {(IHEC-PGR/2021/DM/M.Ch/Jan/02), CTRI Registration: CTRI/2022/01/039199.} Results: No significant differences were observed between the traction and non-traction groups regarding postoperative blood loss ( p-value- 0.632), fall in hemoglobin ( p-value- 0.719) and hematocrit ( p-value- 0.937) levels, and length of postoperative hospital stay ( p-value- 0.797). However, the traction group reported significantly higher postoperative pain scores ( p-value < 0.001) and increased analgesic requirements ( p-value < 0.001). Conclusion: The study suggests that 12-hours catheter traction after mTURP does not reduce blood loss and is associated with increased postoperative pain.
Low-dose metformin suppresses hepatocellular carcinoma metastasis via the AMPK/JNK/IL-8 pathway
Authors: Zhao Chengwen , Zheng Lu , Ma Yuting , Zhang Yue , Yue Chanjuan , Gu Feng , Niu Guoping , Chen Yongqiang 
Published: April 2024

Background and objectives Metformin, an oral hypoglycemic drug, has been suggested to possess antitumour activity in several types of cancers. Additionally, interleukin-8 (IL-8) has been reported to be involved in the development and metastasis of many cancers. However, the effect of metformin on IL-8 expression in hepatocellular carcinoma (HCC) remains unclear. Therefore, this study aimed to investigate whether metformin could inhibit IL-8 expression to exert an inhibitory effect on HCC progression. Materials and methods The IL-8 levels were measured in the plasma of 159 HCC patients (86 men, 73 women; average age 56 years) and in the culture supernatant of HCC cells (Hep3B and HuH7) using flow cytometry. In addition, the protein expression levels of IL-8 were also validated by the Human Protein Atlas (HPA) database. The prognostic value of IL-8 was evaluated using the Kaplan–Meier Plotter database. The association between IL-8 expression and immune checkpoints was estimated using the TIMER and The Cancer Genome Atlas (TCGA) databases. What’s more, bioinformatics analysis, western blotting, and transwell assays were conducted to illustrate the molecular mechanism of metformin (≤1 mM) on IL-8 in HCC. Results IL-8 expression was found to be increased in the plasma of HCC patients, which is consistent with the expression of IL-8 in HCC cells and tissues. High expression of IL-8 was significantly related to poor prognosis. In addition, IL-8 was positively correlated with immune checkpoints in HCC. Notably, we found that low-dose metformin could inhibit the secretion of IL-8 by HCC cells and the migration of HCC cells. Mechanistically, low-dose metformin significantly suppresses HCC metastasis mainly through the AMPK/JNK/IL-8/MMP9 pathway. Conclusion The results indicate that low-dose metformin can inhibit HCC metastasis by suppressing IL-8 expression. Targeting the AMPK/JNK/IL-8 axis may be a promising treatment strategy for patients with HCC metastasis.
Real World Data of Viral Suppression With Darunavir/Cobicistat and Dolutegravir/Rilpivirine Among Treatment-Experienced Patients Living With Multidrug-Resistant HIV
Authors: Samuel Preethi S. , Olaleye Folake , Longo Maria , Berkowitz Leonard 
Published: April 2024

Background: Despite the effectiveness of the TRIO regimen in maintaining viral suppression, as seen in the ANRS 139 TRIO trial, one drawback is the high pill burden. However, with the development of newer antiretrovirals, this regimen can be simplified. The combination of both co-formulated darunavir/cobicistat and dolutegravir/rilpivirine keeps the integrity of the TRIO regimen while decreasing daily pill count from 12 to 2 tablets daily. The purpose of this case series is to demonstrate the efficacy of this regimen as there is a current lack of data. Methods: This case series included patients with no resistance to dolutegravir, rilpivirine, or darunavir, who were switched to the modified TRIO regimen between June 1st 2018 to June 1st 2022. The primary outcome was the proportion of patients with plasma HIV-RNA levels <50 copies/mL by 24 weeks. Results: At week 24, all patients (n = 9) had a HIV-RNA <50 copies/mL. At week 48, one patient did not have a VL available. However, out of the remaining 8 patients, all maintained an HIV-RNA of <50 copies/mL at week 48. Conclusion: HIV-RNA levels remained suppressed when patients were switched to the modified TRIO regimen. In addition, the pill burden was reduced which can add to overall patient satisfaction.
Treatment Engagement and Outcomes in Parent–Child Interaction Therapy with Mothers with a History of ADHD: A Case Series
Authors: Bailey Brittany A. , Heaton Shelley C. , McNeil Cheryl B. , Nelson Melanie M. 
Published: April 2024

Behavioral parent training is the recommended intervention for young children with disruptive behavior and/or attention-deficit/hyperactivity disorder (ADHD). Parent–child interaction therapy (PCIT) is an empirically supported behavioral parent-training program for families of children ages 3–6 years old. Behavioral parent-training programs, including PCIT, rely on parents as the primary agents of therapeutic change. Parents who face barriers to adequate engagement with these programs may also struggle to implement the changes necessary for children’s behavior to improve. Parental characteristics that may prevent treatment engagement, however, are seldom considered in the research literature or in clinical practice. The current case series describes engagement indicators in three mothers taking part in PCIT. Each mother has a history of diagnosed or suspected ADHD, and this series explores their ADHD-related symptoms as they relate to the treatment of their child’s behavior.
Culture Production and Consumption in Post-COVID Era: A Meta-Analysis of OTT Industry in India
Authors: Srivastav Sonali , Rai Shikha 
Published: April 2024

Web series and video on demand services destabilised and efficiently replaced popular entertainment in the past one year, due to the coronavirus disease (COVID-19) pandemic. The subsequent lockdown not only impacted the traditional creative industries, such as TV and films, but it has also catalysed the way narratives are produced and consumed over the internet. Narratives on the web have been posing challenges to traditional storytelling since the past decade, but the changes in the Indian market have been slow until this year. The industry has also been studied extensively from the perspective of various disciplines, film studies, marketing, psychology, and communication being a few of them. These studies have elaborated upon the evolution of the industry, its popularity, challenges and roadblocks specifically in relation to the Indian market. The study in concern tries to trace the evolution of the industry in comparison to the predictions. It tries to verify if the predictions and scope have been met by trajectory and what quantum of growth can be credited to the COVID pandemic lockdown period. This research starts with gathering studies conducted on the industry, specifically in the Indian market, since its existence. With the help of a qualitative meta-analysis, this paper tries to analyse the trends and trajectories predicted vis-a-vis the actual growth in numbers over the years, specifically in the post-COVID era. Researchers aim to suggest a model on the production–consumption patterns and the functioning of the industry.
Protein S Deficiency Resulting in Recurrent Arterial Ischemic Strokes in a Young Female: A Case Report
Authors: Sheetal S. , Gladson Nikhil , George Joseph , Daniel Jennifer 
Published: April 2024

Introduction: Ischemic stroke in younger adults has been increasing over the years. It is often challenging to identify the underlying etiology and pathogenesis of stroke in the young. Inherited thrombophilias contribute to about 1%–4% of ischemic strokes in the young. Of the inherited thrombophilias, isolated protein S deficiency is an important risk factor for the development of arterial ischemic strokes. It is commonly associated with venous thrombosis but it is rarely associated with arterial ischemic strokes, contributing to 4%–12% of young strokes. Case Description: We report the case of a 38-year-old female who presented with acute onset of weakness in her left upper and lower limbs, whose magnetic resonance imaging brain showed evidence of recurrent arterial ischemic strokes and was detected to have an isolated protein S deficiency. Conclusion: It is very important to identify the underlying etiology in a young patient with stroke. Although protein S deficiency is commonly associated with venous thrombosis, it can be rarely associated with arterial ischemic strokes; hence, thrombophilia workup should always be done in the evaluation of young stroke.
Unicystic Ameloblastoma Mural Variant: A Case Report
Authors: Akhtar Soubia , Khan Ashar Masood , Afzal Yumna , Ikram Mubasher 
Published: April 2024

Background: Ameloblastomas are a rare type of benign neoplastic tumors that are locally invasive and make up around 1% of all head-and-neck tumors. Mostly diagnosed in people between the ages of 30 and 60 years, it has a global incidence of about 0.5% of cases per million person years. Ameloblastomas are classified as multicystic, unicystic, peripheral, and desmoplastic variants. Unicystic ameloblastomas (UAs), accounting for about 6% of the cases, have a high recurrence rate. It is histologically divided into luminal, intraluminal, and mural types. As the mural variant is aggressive and has the highest chance of recurrence, radical resection of tumor is required. Case Presentation: A case of 47-year-old patient, diagnosed as unicystic mural variant of ameloblastoma presented to us in March 2023 at the department of head-and-neck surgery at a tertiary care setup in Karachi, Pakistan. Postoperatively, the patient is now on 6-month follow-up with no residual or recurrence report as of yet. Conclusion: We report a rare case of UA mural variant in the right mandible, which highlights the importance of prompt diagnosis and treatment of this type of ameloblastoma, particularly in a location where they can cause significant damage.
Comparison of Clinical Outcome of Bacterial Colonization between Nasogastric and Orogastric Enteral Feeding Tubes in Neonates in the Neonatal Intensive Care Unit
Authors: Soumya M. , Malapur Rajanikanth S. 
Published: April 2024

Introduction: Enteral feeding tubes are commonly utilized in the neonatal intensive care unit (NICU) due to the underdevelopment of coordination between sucking, swallowing, and breathing, or due to various diseases affecting the respiratory, cardiovascular, gastrointestinal, or neurological systems. The aim of the study was to investigate the differences in bacterial colonization patterns in hospitalized infants who received enteral feeding through either nasogastric (NG) or orogastric (OG) feeding tubes. Materials and Methods: This study was a hospital-based cross-sectional investigation that was carried out on infants who were admitted to the NICU. The NICU gathered feeding tubes throughout 4 months, beginning in August 2022 and continuing through December 2022. In addition, informed consent was collected from the participant’s parents or legal guardians for the entire group of people who took part in the research. The fact that the patient participated in this study had no bearing on the level of care that they were given. The research team gave serious consideration to recruiting any of the newborns who were receiving medical attention in the NICU and who had a feeding tube inserted during the time that sample collection was taking place. The infants did not receive any probiotics as a form of treatment in any of the cases. Results: Infants with NG tubes had a significantly higher number of C-sections ( P = 0.04), infants with NG tube were exclusively breastfed ( P = 0.02), and one or more dose of antenatal steroids was administered more in infants with OG tube ( P = 0.04). The most common types of bacteria found in NG and OG tubes were Proteobacteria (with a mean relative abundance of 50% and 60%, respectively), Firmicutes (with a mean relative abundance of 33% and 23%, respectively), and Actinobacteria (9% and 7%, respectively). Conclusion: Oral versus nasal feeding tube insertion was found to have a greater influence on bacterial colonization than any of the other clinical factors that were evaluated.