bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A New General Synthesis of Isomeric Nucleosides.
Authors: Bera Sanjib , Nair Vasu 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unexpected Results and Recourse in Process Optimization of Nucleoside 3′‐O‐Succinates
Authors: Song Quanlai , Sanghvi Yogesh S. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies on Sialoglycoconjugates. Part 120. The First, Efficient Synthesis of Novel SLex Neoglycolipids Containing N‐Deacetylated and Lactamized Sialic Acid: Key Ligand Structures for Selectin Binding.
Authors: Otsubo Nobumasa , Yamaguchi Masanori , Ishida Hideharu , Kiso Makoto 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Enyne Metathesis Approach to the Synthesis of the 1,3‐Diene System of Mycothiazole.
Authors: Rodriguez‐Conesa Sara , Candal Paloma , Jimenez Carlos , Rodriguez Jaime 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of trans‐γ‐Oxo‐α,β‐unsaturated Carboxylic Acids, the Intermediates for Patulolide A and Pyrenophorin.
Authors: Davis K. Joju , Bhalerao U. T. , Rao B. Vittal 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in Antibody Catalysis of Cycloaddition Reactions
Authors: Tremblay Martin R. , Dickerson Tobin J. , Janda Kim D. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Coordination and Transformation of Arene Rings by Transition Metal Carbonyl Cluster Complexes
Authors: Brait Sabrina , Deabate Stefano , Knox Selby A. R. , Sappa Enrico 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photomagnetic and Magneto‐Optical Effects of Functionalized Metal Polycyanides
Authors: Ohkoshi Shin‐Ichi , Hashimoto Kazuhito 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Modern Sample Preparation Methods in Chemical Analysis
Authors: Theodoridis Georgis , Papadoyannis I. N. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thermodynamic Estimate of pKa Values of the Carboxylic Acids in Aqueous Solution with the Density Functional Theory
Authors: Zeng Yue , Qian Haiyan , Chen Xianglan , Li Zelin , Yu Shangci , Xiao Xiaoming 
Published: June 2010

AbstractThe 96 pKa values of 85 carboxylic acids in aqueous solution were calculated with the density functional theory method at the level of B3LYP/6‐31+G(d,p) and the polarizable continuum model (PCM) was used to describe the solvent. In the calculations of pKa values, the dissociation Gibbs free energies were directly calculated using carboxylic acid dissociation reactions in aqueous solution, i. e., no thermodynamic cycle was employed, which is different from the previous literatures. A highly significant correlation of R2=0.95 with a standard deviation (SD) of 0.36 between the experimental pKa values and the calculated dissociation Gibbs free energies [ΔG(calc.)] was found. The slope of pKa vs. (G(calc.)/(20303RT) is only 47.6% of the theoretically expected value, which implies that the ΔG(calc.) value from the theoretical calculation is larger than the actual one for all 85 carboxylic acids studied. Thus, by adding the 0.476 scaling‐factor into the slope, we can derive a reliably procedure that can reproduce the experimental pKa values of carboxylic acids. The pKa values furnished by this procedure are in good agreement with the experimental results for carboxylic acids in aqueous solution.
Synthesis, Characterization and Thermal Behaviors of 4‐Amino‐5‐nitro‐1,2,3‐triazole (ANTZ) and Its Derivatives
Authors: Wang Bozhou , Li Jizhen , Huo Huan , Fan Xuezhong , Fu Xiaolong , Zhou Cheng 
Published: June 2010

Abstract4‐Amino‐5‐nitro‐1,2,3‐triazole (ANTZ) and its derivatives, such as 2‐(4‐amino‐5‐nitro‐1,2,3‐trazole‐1‐yl)‐1,3,5‐trinitrobenzene (T‐ANTZ) and 4‐amino‐5‐nitro‐1,2,3‐triazole (M‐ANTZ), were synthesized and characterized, whose structures were confirmed by IR, NMR and elemental analysis. The thermal behaviors of ANTZ, T‐ANTZ and M‐ANTZ were studied by the methods of DSC and TG‐DTG, and the results showed that there is an obvious melting process of ANTZ with melting point of 278.38°C, while there is no melting process in the thermal behavior of T‐ANTZ and M‐ANTZ (the derivatives of ATNZ).
Enantioselective Fluorescent Sensors for N‐Boc‐Protected Amino Acid Anions Based on BINOL
Authors: Xu Kuoxi , Bu Zhanwei , Huang Kejing , Zhao Jin , Wang Chaojie 
Published: June 2010

AbstractThe four novel derivatives of BINOL have been prepared and the structures of these compounds characterized by IR, MS, 1H and 13C NMR spectroscopy and elemental analysis. The enantioselective recognition of these receptors has been studied by fluorescence titration and 1H NMR spectroscopy. The receptors exhibited different chiral recognition abilities towards N‐Boc‐protected amino acid anions and formed 1:1 complexes between host and guest. Receptor s exhibit excellent enantioselective fluorescent recognition ability towards the amino acid derivatives.
Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the sn‐2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines
Authors: Byun Hoe‐Sup , Bittman Robert , Samadder Pranati , Arthur Gilbert 
Published: June 2010

AbstractAnalogues of 1‐O‐hexadecyl‐sn‐3‐glycerophosphonocholine (compounds 1–4) or sn‐3‐glycerophosphocholine (compound 5) bearing a carbamate or dicarbamate moiety at the sn‐2 position were synthesized and evaluated for their antiproliferative activity against cancer cells derived from a variety of tissues. Although all of the compounds are antiproliferative, surprisingly the carbamates (1 and 2) are more effective against the hormone‐independent cell lines DU145 and PC3 than toward other cancer cell lines we examined. This selectivity was not observed with the dicarbamates (3 and 4). Phosphocholine carbamate analogue 5 is as effective against the prostate cancer cell lines as the corresponding phosphonocholine analogue 1. Cell death induced by 2′‐(trimethylammonio)ethyl 4‐hexadecyloxy‐3(R)‐N‐methylcarbamoyl‐1‐butanephosphonate (carbamate analogue 2) appeared to be mediated by apoptosis, as assessed by caspase activation and loss of mitochondrial membrane potential. The in vivo activity of 2 was evaluated in a murine prostate cancer xenograft model. Oral and intravenous administration showed that 2 is effective in inhibiting the growth of PC3 tumors in Rag2M mice. Our studies show that the glycerolipid carbamates reported herein represent a class of prostate‐cancer‐selective cytotoxic agents.
High response rate after intratumoral treatment with interleukin‐2
Authors: Weide Benjamin , Derhovanessian Evelyna , Pflugfelder Annette , Eigentler Thomas K. , Radny Peter , Zelba Henning , Pföhler Claudia , Pawelec Graham , Garbe Claus 
Published: June 2010

AbstractBACKGROUND:Systemic high‐dose interleukin‐2 (IL‐2) achieved long‐term survival in a subset of patients with advanced melanoma. The authors reported previously that intratumorally applied IL‐2 induced complete local responses of all metastases in >60% of patients. The objectives of the current study were to confirm those results in a larger cohort and to identify patient or regimen characteristics associated with response.METHODS:Patients with melanoma who had a median of 12 injectable metastases received intratumoral IL‐2 treatments 3 times weekly until they achieved clinical remission. The initial dose of 3 million international units was escalated, depending on the individual patient's tolerance.RESULTS:Forty‐eight of 51 patients were evaluable. Only grade 1/2 toxicity was recorded. A complete response that lasted ≥6 months was documented in 70% of all injected metastases. A complete local response of all treated metastases was achieved in 33 patients (69%), including 11 patients who had between 20 and 100 metastases. Response rates were higher for patients who had stage III disease compared with patients who had stage IV disease. No objective responses of distant untreated metastases were observed. The 2‐year survival rate was 77% for patients with stage IIIB/IIIC disease and 53% for patients with stage IV disease. Efficacy and survival did not differ between patients who had ≥20 lesions and patients who had <20 lesions.CONCLUSIONS:Intratumoral IL‐2 treatment elicited complete local responses in a high percentage of patients. Further studies will be required to investigate the mode of action of this treatment and its impact on survival. Cancer 2010. © 2010 American Cancer Society.
Role of Multipole Moments in Electric‐Field‐Induced Order of Dense Molecular Systems
Authors: Acebal Pablo , Carretero Luis , Blaya Salvador 
Published: June 2010

AbstractA new model is developed to describe the orientational order of dense molecular systems under an applied external electric field as a function of the n‐particle distribution functions of a system under no external perturbation. From an approximation of this expression, the effects of several variables on this orientational order, such as the microscopic properties of the oriented molecules (the molecular geometry and multipole moments) and the solvent or matrix properties, are studied. The theoretical predictions show that, for a correct description of the orientational order, quadrupole and octupole moments must be included, as they play an important role in the orientational order achieved, depending on the molecular geometry. Furthermore, to verify the validity of the model, theoretical predictions are compared with experimental results, and show a good concordance.
Construction and factorial validation of a short form of the Self‐Compassion Scale
Authors: Raes Filip , Pommier Elizabeth , Neff Kristin D. , Van Gucht Dinska 
Published: June 2010

AbstractThe objective of the present study was to construct and validate a short‐form version of the Self‐Compassion Scale (SCS). Two Dutch samples were used to construct and cross‐validate the factorial structure of a 12‐item Self‐Compassion Scale–Short Form (SCS–SF). The SCS‐SF was then validated in a third, English sample. The SCS–SF demonstrated adequate internal consistency (Cronbach's alpha ≥ 0.86 in all samples) and a near‐perfect correlation with the long form SCS (r ≥ 0.97 all samples). Confirmatory factor analysis on the SCS–SF supported the same six‐factor structure as found in the long form, as well as a single higher‐order factor of self‐compassion. The SCS–SF thus represents a reliable and valid alternative to the long‐form SCS, especially when looking at overall self‐compassion scores. Copyright © 2010 John Wiley & Sons, Ltd.Key Practitioner Message:• The 12‐item Self‐Compassion Scale–Short Form (SCS–SF) in Dutch and English offers an economical alternative to the long Self‐Compassion Scale (SCS) to measure self‐compassion. Although the original long form of the SCS is reduced to half, the SCS–SF is reliable and has the same factorial structure as the original scale.
Analysis and enhancement of multi‐channel MAC protocol forad hocnetworks
Authors: Kao Hui‐Hsiang , Wu Peng‐Jung , Lee Chung‐Nan 
Published: June 2010

AbstractIn this paper, an analytical model is proposed to calculate the network throughput of dedicated control channel protocols that are designed to schedule multiple packets to be transmitted on different data channels simultaneously. Based on the analytical model, a scheme by tuning the initial contention window size is proposed to maximize the network throughput. We also present a novel multi‐channel MAC protocol for single‐hop scenario. Simulation results show that the proposed model is capable of modeling the behaviors of dedicated control channel protocols accurately. Furthermore, the proposed scheme can reduce the cost of collisions and enhance the network throughput up to 22% for 1 kB packet size and 80 nodes. Compared with other dedicated control channel protocols, the proposed protocol can schedule more control packets and use multiple channels more efficiently. Copyright © 2010 John Wiley & Sons, Ltd.
Generation and characterization of Atoh1‐Cre knock‐in mouse line
Authors: Yang Hua , Xie Xiaoling , Deng Min , Chen Xiaowei , Gan Lin 
Published: June 2010

AbstractConfocal microscope image of a neonatal Atoh1Cre/+; R26R‐lacZ mouse inner ear crista. Hair cells are labeled with anti‐MYO6 (red). Anti‐lacZ ‐green‐ immunolabeling reveals the hair and supporting cells originated from Atoh1‐lineage. For more information, see the article by Yang et al. in this issue. © 2010 Wiley‐Liss, Inc.
Generalised approach for performance analysis of SIR‐based multiple selection diversity over constant correlated α – µ fading channels
Authors: Anastasov Jelena A. , Stefanović Mihajlo Č. , Panić Stefan R. , Mosić Aleksandar V. 
Published: June 2010

AbstractSelection combining (SC) is commonly used space‐diversity technique in wireless communication systems to alleviate effects of channel fading and interference influence. In this paper, we analyse the performance of multibranch signal‐to‐interference‐ratio (SIR)‐based SC diversity over correlated α – µ fading channels with arbitrary parameters. The novel formulae for the probability density function (pdf) and cumulative distribution function (cdf) of output SIR are derived. Some numerical and simulation results are obtained pointing out the effects of fading severity, level of correlation, input SIR unbalance and diversity order to the outage probability. Also, the average error probability for several modulation schemes is numerically evaluated. Copyright © 2010 John Wiley & Sons, Ltd.
Comparison of different channel estimation approaches for Block‐IFDMA
Authors: Sohl A. , Klein A. 
Published: June 2010

AbstractIn this paper, channel estimation for Discrete Fourier Transform (DFT) precoded Orthogonal Frequency Division Multiple Access (OFDMA) with block‐interleaved subcarrier allocation per user, which is denoted as Block‐Interleaved Frequency Division Multiple Access (B‐IFDMA), is considered. Recent investigations are presented for new pilot insertion methods which exhibit different impact on the Peak‐to‐Average Power Ratio (PAPR) of the transmit signal and offer different possibilities of positioning the pilots in frequency domain. Each of these pilot insertion methods is combined with a corresponding algorithm to estimate the Channel Variations in Frequency Domain (CVFD). The Channel Variations in Time Domain (CVTD) are estimated by an improved Decision Directed Channel Estimation (DDCE) with joint iterative Wiener filtering which reduces the error propagation by considering certain neighbouring symbols jointly in each iteration step. The DDCE is compared to a Wiener interpolation filter for the estimation of CVTD. The combinations of pilot insertion method, estimation algorithm for CVFD and CVTD are compared in terms of the PAPR and the Mean Square Error (MSE) performance. Thereby, the impact of different pilot positions in frequency domain and time domain is investigated. Copyright © 2010 John Wiley & Sons, Ltd.
Patient‐reported outcome measures in the NHS: new methods for analysing and reporting EQ‐5D data
Authors: Devlin Nancy J. , Parkin David , Browne John 
Published: June 2010

AbstractIn a landmark move, the UK Department of Health (DH) has introduced the routine collection of patient‐reported outcome measures (PROMs) to measure the performance of health‐care providers. From April 2009, generic (EQ‐5D) and condition‐specific PROMs are being collected from patients before and after four surgical procedures; eventually this will be extended to include a wide range of other NHS services. The aim of this article is to report analysis of the EQ‐5D data generated from a pilot study commissioned by the DH and to consider the implications for the use of EQ‐5D data in performance indicators and measures of patient benefit. We present two new methods that we have developed for analysing and displaying EQ‐5D profile data: a Paretian Classification of Health Change and a health profile grid. We show that EQ‐5D profile data can be readily analysed to generate insights into the nature of changes in patient‐reported health that would be obscured by summarising these profiles by their index scores, or focusing just on the post operative outcomes. Our methods indicate differences between providers and between sub‐groups of patients. Our results also show striking differences in changes in EQ‐5D profiles between surgical procedures, which require further investigation. Copyright © 2010 John Wiley & Sons, Ltd.
A comparison of peak and plate electrodes in electrical resistivity tomography: application to the chalky groundwater of the Beauvais aquifer (northern part of the Paris basin, France)
Authors: Zouhri Lahcen , Lutz Pascale 
Published: June 2010

AbstractElectrical resistivity tomography was used in order to explore an experimental site of the LaSalle Beauvais Polytechnic Institute (France). The test was conducted along a profile line of 315 m length, using 64 electrodes deployed at an inter‐electrode spacing of 5 m, and the data were recorded using gradient, Wenner and pole–dipole arrays. The performance of plate electrodes (non‐conventional flat‐based) is compared with the performance of peak electrodes (conventional spike). The hydrogeophysical investigation of the chalk aquifer system of Beauvais shows that the performance of plate electrodes is satisfactory, leading to inversions of small root‐mean‐square errors. Peak and the plate electrodes were tested before and after injection of a salt tracer in the piezometer of the experimental site. The study demonstrates the usefulness of plate electrodes (efficient, less time consuming) and the possibility of aquifer characterization by a salt tracer. Copyright © 2010 John Wiley & Sons, Ltd.
Optimal fluorescein dose for intravenous application in miniprobe‐based confocal laser scanning microscopy in pigs
Authors: Becker Valentin , van den Broek Frank J. , Buchner Anna M. , Dekker Evelien , Wallace Michael B. , von Delius Stefan , Schneider Armin , Schmid Roland M. , Meining Alexander 
Published: June 2010

AbstractProbe‐based confocal laser scanning endomicroscopy (pCLE) enables in‐vivo histopathology during ongoing endoscopy. The most frequently used fluorophore is fluorescein sodium administered intravenously. Despite the increased use of pCLE, there are hardly any data on the ideal fluorescein concentration. Therefore, rectal mucosa of pigs was examined after injection (i.v.) of fluorescein as a single bolus (0.1 ml/kg body weight) in different concentrations (0.5%, 1%, 2%, 5%, 10%). Video sequences were recorded after 1, 5 and 60 min. For objective evaluation signal‐to‐noise ratio (SNR) was computed. For subjective evaluation, video sequences were randomized and blindly evaluated by experienced endomicroscopists. In total, 19037 images were analyzed. The mean SNR increased from the lowest (0.5%; SNR 6.75, range 3.55) to the highest concentration (10%; SNR 9.11, range 3.18). Subjective evaluation demonstrated best image quality with fluorescein concentration of 5%. In conclusion, pCLE shows best results using single injection of IV fluorescein 5%. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Application of Terahertz Time‐Domain Spectroscopy in Intracellular Metabolite Detection
Authors: Wang Changlei , Gong Jixian , Xing Qirong , Li Yanfeng , Liu Feng , Zhao Xueming , Chai Lu , Wang Chingyue , Zheltikov Aleksei M. 
Published: June 2010

AbstractUsing terahertz time‐domain spectroscopy (THz‐TDS), we have investigated the THz spectra of astaxanthin and riboflavin and the spectra of two kinds of cell, haenatcoccus plusivalis and bacillus subtilis, which could produce astaxanthin and riboflavin, respectively, during their metabolite process. Riboflavin was found to be much more absorptive to THz radiation and have richer spectral characteristics than astaxanthin. As an intracellular metabolite, riboflavin could be distinguished from the cells by using THz‐TDS. The technique has potential applications in high‐throughput screening of industrial strains. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)