bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can It Be a Gamechanger? Interrogating the Prospects of Decolonization Through Public History in Japan
Authors: Tozawa Emi 
Published: May 2024

Abstract
As a historical settler and colonizer in Asia, yet a state not colonized by European countries, Japan and its colonial history seem to have been left out from the debates on public history as a decolonizing process, due to the field having arguably been Eurocentric. This article interrogates the extent to which public history could serve as a vehicle to decolonize the history-making process in Japan and demonstrates the challenges of decolonizing through public history within Japan’s national framework due to nationalistic or patriotic silencing and censorship. Such nationalistic public history is rooted in Japan’s narratives of victimhood fostered in its course of history, including the ‘inferior’ position against the West or the experience of the atomic bombs. Moreover, Japan’s historical division between the internal and external colonies as well as its nationalistic, defensive attitude towards the history of external colonialism have played significant roles in burying its settler colonial past. To include narratives about the internal and external colonial victims, I argue that both Eurocentric decolonization and academia-centered public history in Japan need to be, in themselves, decolonized so that they provide more nuanced approaches to Japan’s colonial past. Furthermore, given that narratives of the colonial past in national history projects can be silenced under nationalistic victimhood, this article suggests that transnational collaborative public history could disconnect historical narratives from nationalistic discourses of victimhood, gathering more sympathy beyond Japan and supporting efforts towards decolonization. The overall article eventually contributes to decolonizing the Eurocentric debates on ‘decolonization through public history.’
Regional evaluation of global geopotential models and three types of digital elevation models with ground-based gravity and GNSS/levelling data using several techniques over Sudan
Authors: Osman Anas , Elsaka Basem , Anjasmara Ira Mutiara 
Published: May 2024

Abstract
To evaluate the performance of the global geopotential models (GGMs) in a more unbiased way, ground-based gravity and GNSS/levelling datasets are highly required. In this study, the eight latest releases of the satellite-only and combined GGMs are evaluated on the regional scale using the available terrestrial gravity and GNSS/Levelling data over Sudan, considering the spectral consistency issue by applying the spectral enhancement method (SEM). The evaluation process consists of three stages: firstly, the eight GGMs are evaluated globally with each other by using different degree variances in terms of geoid heights, gravity anomalies, and signal-to-noise ratio (SNR); secondly, the GGMs are compared against the Earth Gravitational Model 2008 (EGM2008) on a regional scale over Sudan; thirdly, apply the SEM strategy by incorporating high (SEM_WITHOUT_RTM technique) and very-high (SEM technique) frequencies of the gravity field spectrum from the EGM2008 and high-resolution residual terrain model (RTM), respectively. For reliable robustness of the latter evaluation process, three different DEMs are used, namely, SRTM30, ASTER30, and GTOPO30. Our findings on the evaluation process using SEM_WITHOUT_RTM technique show improved gravity anomalies solutions regarding differences of standard deviations (STD) from 19–20.7 mGal to about 14 mGal. When applying the SEM technique, more improvements are achieved, providing STD differences in gravity anomalies and geoid heights of about 12 mGal and 45 cm, respectively. Among the three applied DEMs, it has been found that despite the slight refinements, the ASTER30 and GTOPO30 models show better performance than the SRTM30 model.
Vaginal matrix metalloproteinase-9 (MMP-9) as a potential early predictor of preterm birth
Authors: Davis Jay A. , Baker David , Peresleni Tatyana , Heiselman Cassandra , Kocis Christina , Demishev Michael , Garry David J. 
Published: May 2024

Abstract

Objectives
To evaluate the differences in vaginal matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMPs) in pregnant patients with a history of prior preterm birth compared with controls.

Methods
A prospective cohort pilot study recruited patients during prenatal care with history of prior spontaneous preterm birth (high-risk group) or no history of preterm birth (low-risk/controls). Inclusion criteria were singleton gestation at 11–16 weeks and between 18 and 55 years of age. Exclusion criteria were diabetes mellitus, hypertension, diseases affecting the immune response or acute vaginitis. A vaginal wash was performed at time of enrollment, and patients were followed through delivery. Samples were analyzed using semi-quantitative analysis of MMPS and TIMPS. The study was approved by the IRB and a p-value <0.05 was considered significant.

Results
A total of 48 pregnant patients were recruited: 16 with a history of preterm birth (high-risk group) and 32 with no history of preterm birth (low-risk group/controls). Groups were similar in age, race, BMI, and delivery mode. The high-risk group had more multiparous women (100 vs. 68.8 %; p=0.02), a greater preterm birth rate (31.2 vs. 6.3 %; p=0.02), and a lower birth weight (2,885 ± 898 g vs. 3,480 ± 473 g; p=0.02). Levels of vaginal MMP-9 were greater in high-risk patients than low-risk patients (74.9 % ± 27.0 vs. 49.4 % ± 31.1; p=0.01). When dividing the cohort into patients that had a spontaneous preterm birth (7/48, 14.6 %) vs. those with a term delivery (41/48, 85.4 %), the vaginal MMP-9 remained elevated in the cohort that experienced a preterm birth (85.46 %+19.79 vs. 53.20 %+31.47; p=0.01). There were no differences in the other MMPS and in TIMPs between high and low-risk groups.

Conclusions
There was an increase in vaginal MMP-9 during early pregnancy in those at high risk for preterm birth and in those who delivered preterm, regardless of prior pregnancy outcome. Vaginal MMP-9 may have potential as a marker of increased risk of preterm birth.
A generative approach to frame-level multi-competitor races
Authors: Stokes Tyrel , Bagga Gurashish , Kroetch Kimberly , Kumagai Brendan , Welsh Liam 
Published: May 2024

Abstract
Multi-competitor races often feature complicated within-race strategies that are difficult to capture when training data on race outcome level data. Models which do not account for race-level strategy may suffer from confounded inferences and predictions. We develop a generative model for multi-competitor races which explicitly models race-level effects like drafting and separates strategy from competitor ability. The model allows one to simulate full races from any real or created starting position opening new avenues for attributing value to within-race actions and performing counter-factual analyses. This methodology is sufficiently general to apply to any track based multi-competitor races where both tracking data is available and competitor movement is well described by simultaneous forward and lateral movements. We apply this methodology to one-mile horse races using frame-level tracking data provided by the New York Racing Association (NYRA) and the New York Thoroughbred Horsemen’s Association (NYTHA) for the Big Data Derby 2022 Kaggle Competition. We demonstrate how this model can yield new inferences, such as the estimation of horse-specific speed profiles and examples of posterior predictive counterfactual simulations to answer questions of interest such as starting lane impacts on race outcomes.
A Marketplace for Honest Ideas
Authors: Khorasanee Kasim 
Published: May 2024

Abstract
The marketplace of ideas is a colourful metaphor with a long history of being used to argue for freedom of speech. This paper draws on its historical antecedents to begin with an orthodox understanding of the metaphor whereby the absence of substantive regulation is taken to be conducive to the good functioning of both economic markets and public discourse. This anti-regulation reading is then challenged by analysing a series of legal cases showcasing prohibitions on misrepresentation and fraud. These speech regulations are explained by the economics literature on information asymmetry, which illustrates how honesty regulations maintain good market functioning by facilitating credible reliance by market participants on one another’s assertions. What is thereby proposed is a re-imagining of the marketplace of ideas metaphor which lends support to honesty regulations in the realm of public speech. One potential analogue for these legal and economic findings is identified in the work of Shiffrin and her arguments for deontological sincerity requirements in the public sphere.
Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID
Authors: Guo Ming , Shang Shunlai , Li Mengfei , Cai Guangyan , Li Ping , Chen Xiangmei , Li Qinggang 
Published: May 2024

Abstract
COVID-19 posed a major challenge to the healthcare system and resources worldwide. The popularization of vaccines and the adoption of numerous prevention and control measures enabled the gradual end of the COVID-19 pandemic. However, successive occurrence of autoimmune diseases in patients with COVID-19 cannot be overlooked. Long COVID has been the major focus of research due to the long duration of different symptoms and the variety of systems involved. Autoimmunity may play a crucial role in the pathogenesis of long COVID. Here, we reviewed several autoimmune disorders occurring after COVID-19 infection and the pathogenesis of long COVID.
Synthesis, MTT assay, 99m-Technetium radiolabeling, biodistribution evaluation of radiotracer and in vitro magnetic resonance imaging study of P,N-doped graphene quantum dots as a new multipurpose imaging nano-agent
Authors: Mollazadeh Morteza , Fakhari Ashraf , Mortezazadeh Tohid , Mofrad Farshid Babapour , Nazarie Ali Jamali 
Published: May 2024

Abstract
In this study, a new nano-structure, N,P-doped graphene quantum dots (N,P-GQDs), were synthesized as multipurpose imaging agent for performing scintigraphy and magnetic resonance imaging (MRI). Some standard characterization methods were used to identify the nano-structure. In vitro cytotoxicity evaluation using MTT assay revealed that N,P-GQDs nanoparticles had no significant cytotoxicity after 24 and 48 h against normal (MCF-10A) and cancerous (MCF 7) human breast cell line in concentration up to 200 μg/mL. The N,P-GQDs were radiolabeled with Technetium-99m as 99mTc-(N,P-GQDs) and the radiochemical purity was assayed by ITLC concluding RCP ≥ 95 %. The passing of 99mTc-(N,P-GQDs) through 0.1 µm filter demonstrated that 70.8 % of particles were <0.1 µm. In order to perform scintigraphy, the 99mTc-(N,P-GQDs) were injected to female healthy Wistar rats. The results showed that the radio-complex was captured and eliminated just by kidneys. Moreover, in vitro T1-weighted phantom MRI imaging showed that the N,P-GQDs have proper relaxivity in comparison to Dotarem® as a clinically available contrast agent. The results showed that the N,P-GQDs have potential to be considered as a novel and encouraging agent for both molecular MRI and nuclear medicine imagings.
Heliopolis, Funde aus der Nekropole von Ard Neqabet El-Muhamin (1987–88)
Authors: Wagdy Abdelghaffar 
Published: May 2024

Summary
The modern settlements of El-Matariya and Ain Shams are located to the north-east of Cairo, now covering the cemetery of Heliopolis. This necropolis contained many tombs from the Old Kingdom, or even before, which continued to be in use through the Late Period (7th–4th centuries BC). Heliopolis is considered one of the oldest religious cities in the history of ancient Egypt, which has not been systematically and fully excavated. During the rescue excavations of Ard Neqabet El-Muhamin in Ain-Shams East (Heliopolis) in 1987–8, many objects were found. They come from different periods, have different shapes and have been made from different materials. The aim of this research is to study in detail the objects, which stem from the excavations of Ard Neqabet El-Muhamin at Heliopolis which they are kept in El-Matariya’s storerooms and Grand Egyptian Museum, which have not been published completely. These objects have a lot of archaeological information, which need to be published in scientific research, to help date these artifacts and cast light on them.

تقع منطقه المطرية وعين شمس الحالية شمال شرق القاهرة، فوق جبانة هليوبوليس. احتوت هذه الجبانة على العديد من المقابر من عصر الدولة القديمة، والتي استمرت في الاستخدام خلال الفترة المتأخرة. تعتبر هليوبوليس واحدة من أقدم المدن الدينية في تاريخ مصر القديمة، والتي لم يتم التنقيب عنها بشكل منهجي وكامل. أثناء حفائر الإنقاذ في أرض نقابة المحامين في عين شمس الشرقية (هليوبوليس) تم العثور على العديد من اللقى الأثرية من فترات زمنيه مختلفة. الهدف من هذا البحث هو الدراسة التفصيلية لهذه لقطع والتي تم حفظها في مخازن المطرية والمتحف المصري الكبير، والتي لم يتم نشرها من قبل، حيث تحتوي هذه اللقى على الكثير من المعلومات الأثرية، والتي يجب نشرها في بحث علمي، للمساعدة في تحديد تاريخ هذه القطع الأثرية وإلقاء الضوء عليه.
Embrace
Authors: Wood Laura 
Published: May 2024

Laura Wood is an Ottawa-based artist who paints with gestural strokes to create elegant abstract compositions. Her paintings are evocative and emotive as she uses paint and colour to represent, as Wood describes, “what otherwise cannot be expressed with words.”
Her process is intuitive as she is guided by the paint & chance happenings with colour mixing and form. Intentionality happens as she pauses between strokes. This dance back and forth between pure expression and thoughtful mark-making is how her works are created.
Originally from Aurora, Ontario, Woods even at a young age had a rich interior life and art gave her a place to fully express all aspects of her internal experience. Her family’s encouragement led her to pursue her passions and she went on to study and a Bachelor of Fine Arts from the Ontario College of Art and Design University in Canada. She is currently represented in Ottawa, ON at Koyman Galleries.
Risk Factors for Deterioration Events in the Pediatric Acute Care Setting
Authors: Lucey Kate , Jones Roderick C. , Watson J. Andrew , Malakooti Marcelo , Stephen Rebecca J. 
Published: May 2024

OBJECTIVES
Rapid response system (RRS) activations resulting in emergency transfers (ETs) and codes outside the ICU are associated with increased mortality and length of stay. We aimed to evaluate the patient and care team characteristics of RRS activations resulting in ETs and codes outside the ICU (together classified as “deterioration events”) versus those that did not result in a deterioration event.

METHODS
For each RRS activation at our institution from 2019 to 2021, data were gathered on patient demographics and medical diagnoses, care team and treatment factors, and ICU transfer. Descriptive statistics, bivariate analyses, and multivariable logistic regression using a backward elimination model selection method were performed to assess potential risk factors for deterioration events.

RESULTS
Over the 3-year period, 1765 RRS activations were identified. Fifty-three (3%) activations were deemed acute care codes, 64 (4%) were noncode ETs, 921 (52%) resulted in nonemergent transfers to an ICU, and 727 (41%) patients remained in an acute care unit. In a multivariable model, any complex chronic condition (adjusted odds ratio, 6.26; 95% confidence interval, 2.83–16.60) and hematology/oncology service (adjusted odds ratio, 2.19; 95% confidence interval, 1.28–3.74) were independent risk factors for a deterioration event.

CONCLUSIONS
Patients with medical complexity and patients on the hematology/oncology service had a higher risk of deterioration events than other patients with RRS activations. Further analyzing how our hospital evaluates and treats these specific patient populations is critical as we develop targeted interventions to reduce deterioration events.
Chamuangone-enriched rice bran oil ameliorates neurodegeneration in haloperidol-induced Parkinsonian rat model via modulation of neuro-inflammatory mediators and suppression of oxidative stress markers
Authors: S. Alotaibi Badriyah , Saleem Uzma , Ahmad Aqsa , Chaudhary Zunera , Farrukh Maryam , O. Khayat Rana , Alsharif Ifat , A. S. Baokbah Tourki , Albalawi Aishah E. , A. Althobaiti Norah , Ajmal Shah Muhammad , Anam Khairul , F. Alanazi Yasmene , Panichayupakaranant Pharkphoom , Blundell Renald , Sanches Silva Ana 
Published: May 2024

A natural bioactive compound chamuangone extracted from Thai salad Garcinia cowa leaves exhibited robust medicinal properties, targeting central oxidative stress pathways, and having neuroprotective potential. Chamuangone-enriched rice bran oil (CERBO), with 1.97 mg/mL chamuangone, was obtained through green extraction. The study was designed to evaluate the anti-Parkinson’s activity of CERBO in the haloperidol- induced Parkinsonian rat model. Animals were categorized into six groups as control, disease control and treatment groups. Parkinson’s disease (PD)-like symptoms were induced by administration of haloperidol 1 mg/kg, intraperitoneally; CERBO treatment groups received 2.5, 5, and 7.5 mg/kg orally before the administration of haloperidol for 21 days. Neurobehavioral, biochemical, neurochemical, and histopathological studies along with gene expression analysis were performed at the completion of the study. CERBO markedly recover the motor and non-motor PD-like symptoms in treatment groups dose-dependently. The levels of antioxidant enzymes, such as catalase, superoxide dismutase, reduced glutathione, and glutathione peroxidase, increased, while malondialdehyde levels decreased dose-dependently in CERBO-treated groups. CERBO dose-dependent elevations were observed in neurotransmitters (dopamine, serotonin, and noradrenaline). PD-associated specific biomarker (α-synuclein) decreased dose-dependently with downregulation in messenger RNA expression of neuro-inflammatory mediators (interleukin α, interleukin 1β, and tumor necrosis factor-α). Histopathological studies revealed recovery in neuronal loss, formation of Lewy’s bodies, and neurofibrillary tangles in the treatment groups. It was concluded from the data that CERBO possessed good anti-Parkinson’s activity and could be a novel, safe, and effective remedy for the treatment of PD.
Book Review: A Digital Bundle: Protecting and Promoting Indigenous Knowledge Online
Authors: Bane Treasa 
Published: May 2024

When Indigenous Knowledge is made openly available, it enables members of Indigenous communities to resist colonialism to pursue self-determination as well as cultural transformation for Indigenous Peoples and non-Indigenous Peoples alike. Jennifer Wemigwans’ A Digital Bundle: Protecting and Promoting Indigenous Knowledge Online explores what opening cultural heritage entails from an Indigenous perspective.
Enhancing Multiple Sequence Alignment with Genetic Algorithms: A Bioinformatics Approach in Biomedical Engineering
Authors:   Universidad Autónoma de Coahuila, Rios-Willars Ernesto , Velez-Segura Jennifer ,   Universidad Nacional de Colombia, Delabra-Salinas María Magdalena ,   Universidad Autónoma de Coahuila
Published: May 2024

This study aimed to create a genetic information processing technique for the problem of multiple alignment of genetic sequences in bioinformatics. The objective was to take advantage of the computer hardware's capabilities and analyze the results obtained regarding quality, processing time, and the number of evaluated functions. The methodology was based on developing a genetic algorithm in Java, which resulted in four different versions: Gp1, Gp2, Gp3 and Gp4 . A set of genetic sequences were processed, and the results were evaluated by analyzing numerical behavior profiles. The research found that algorithms that maintained diversity in the population produced better quality solutions, and parallel processing reduced processing time. It was observed that the time required to perform the process decreased, according to the generated performance profile. The study concluded that conventional computer equipment can produce excellent results when processing genetic information if algorithms are optimized to exploit hardware resources. The computational effort of the hardware used is directly related to the number of evaluated functions. Additionally, the comparison method based on the determination of the performance profile is highlighted as a strategy for comparing the algorithm results in different metrics of interest, which can guide the development of more efficient genetic information processing techniques.
Comparative analysis of the results of surgical and radiation treatment of stage I kidney cancer
Authors: Sabelnikova Zh. Е. , Sarycheva М. М. , Mozerova Е. Ya. , Vazhenin А. V. , Lozhkov А. А. 
Published: May 2024

Purpose of the study: To conduct a comparative assessment of the results of surgical and radiation treatment of patients with stage I renal cell carcinoma (RCC) in terms of overall survival (OS), progression-free survival (PFS), local control and changes in renal function. Material and methods: From 2011 to 2022 170 patients with stage I RCC were treated at the Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine. We conducted a retrospective study of their treatment results. The first group — 115 patients who underwent surgical treatment of T1N0M0 kidney cancer (mainly in the amount of kidney resection — 85 people), the second group — 55 patients with verified T1N0M0 renal cell carcinoma who underwent stereotactic radiation therapy (SBRT) up to 30–45 Gy in 3 fractions using CyberKnife. SBRT was performed mainly for the treatment of a primary kidney tumor, in 7 cases — for a recurrence of kidney cancer, including 1 patient with recurrent tumors in both kidneys. The average age of patients in the surgery group was 73 years, in the SBRT group — 69.9 years. The average tumor diameter in the operation group was 4.3 cm, in the SBRT group it was 3.5 cm. Results: The median OS in the surgery group was 121 months, but it was not achieved in the SBRT group, since most patients are alive at the time of the study. 1‑year OS in the surgery group and SBRT was comparable (98.9 % and 95.1 %, respectively), but 5‑year OS in the surgery group was significantly higher — 90.2 % vs. 70 % in the SBRT group (p < 0.05). The same trend was noted in the assessment of PFS. In the surgery group, 4 patients out of 115 (3.5 %) had a recurrence in the tumor bed, in all cases after kidney resection, after 28 months in average. In the SBRT group, 42 patients (75 %) according to RECIST 1.1 criteria 6 months after SBRT showed stabilization of the process, in 20 % of cases (11 patients) — a partial response, in 5 % (3 patients) — progressed disease. 1‑year local control was 96.4 %, 1‑year cancer‑specific survival in both groups was 100 %. Renal toxicity was recorded in 38 patients (33 %) in the surgery group and in 10 patients (18 %) in the radiotherapy group 6 months after treatment. On average, glomerular filtration rate decreased by 25 % in the surgery group and by 18 % in the radiotherapy group. We have not noted a single case of a pronounced decrease in GFR, which would require dialysis. Conclusion: Surgery remains the main treatment option for T1N0M0 kidney cancer, but if there are contraindications to surgery, SBRT may be the best option for inoperable patients.