bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the meaning of participation in a community art project: A case study on the Seeming project
Authors: Madyaningrum Monica E. , Sonn Christopher 
Published: December 2010

AbstractIn Australia, community art has drawn significant research attention in regard to its potential as a community development strategy. Despite the fact that researchers have presented evidence for the positive developmental outcomes of participation in community art projects, a gap remains in understanding how and why people's participation in a community art project can lead to those positive outcomes. This research explored the meaning of participation in a community art project from the vantage point of the people who experience it. Ten participants were interviewed about their participation in a community art project (The Seeming) held in Bendigo, Australia. Following thematic analyses we identified three themes of how participants viewed their participation in a community arts project. These themes included giving voice to the silenced, creation of social connections and challenging and reproducing stereotypes. Participation means coming together and the findings highlight the potential of community arts projects for promoting the creation of new relationships and new stories about community. However, there are also problematic stories about self and others that were not deconstructed. It is argued that the settings in which different groups join can be meaningfully extended if there is an explicit concern with consciousness raising and deconstruction of normative stories. Copyright © 2010 John Wiley & Sons, Ltd.
Synthesis, Evaluation, and Mechanism of N,N,N‐Trimethyl‐D‐glucosamine‐(1→4)‐chitooligosaccharides as Selective Inhibitors of Glycosyl Hydrolase Family 20 β‐N‐Acetyl‐D‐hexosaminidases
Authors: Yang You , Liu Tian , Yang Yongliang , Wu Qingyue , Yang Qing , Yu Biao 
Published: December 2010

AbstractGH20 β‐N‐acetyl‐D‐hexosaminidases are enzymes involved in many vital processes. Inhibitors that specifically target GH20 enzymes in pests are of agricultural and economic importance. Structural comparison has revealed that the bacterial chitindegrading β‐N‐acetyl‐D‐hexosaminidases each have an extra +1 subsite in the active site; this structural difference could be exploited for the development of selective inhibitors. N,N,Ntrimethyl‐D‐glucosamine (TMG)‐chitotriomycin, which contains three GlcNAc residues, is a natural selective inhibitor against bacterial and insect β‐N‐acetyl‐D‐hexosaminidases. However, our structural alignment analysis indicated that the two GlcNAc residues at the reducing end might be unnecessary. To prove this hypothesis, we designed and synthesized a series of TMG‐chitotriomycin analogues containing one to four GlcNAc units. Inhibitory kinetics and molecular docking showed that TMG‐(GlcNAc)2, is as active as TMG‐chitotriomycin [TMG‐(GlcNAc)3]. The selective inhibition mechanism of TMG‐chitotriomycin was also explained.
ChemInform Abstract: The Role of Oxygen Stoichiometry on Phase Stability, Structure, and Magnetic Properties of Sr2CoIrO6‐δ.
Authors: Mikhailova D. , Narayanan N. , Gruner W. , Voss A. , Senyshyn A. , Trots D. M. , Fuess H. , Ehrenberg H. 
Published: December 2010

AbstractThe structural features of Sr2CoIrO6‐δ in which the oxygen deficiency can be well controlled and reversibly varied up to δ = 0.33, depend on both temperature and oxygen content and are determined by synchrotron and neutron powder diffraction.
ChemInform Abstract: Structural Study of the Li0.5Na0.5MnFe2(PO4)3 and Li0.75Na0.25MnFe2 (PO4)3 Alluaudite Phases and Their Electrochemical Properties as Positive Electrodes in Lithium Batteries.
Authors: Trad Khiem , Carlier Dany , Croguennec Laurence , Wattiaux Alain , Amara Mongi Ben , Delmas Claude 
Published: December 2010

AbstractLixNa1‐xMnFe2(PO4)3 (x = 0, 0.5, 0.75) is synthesized by a sol—gel method from stoichiometric amounts of Na2CO3, Li2CO3, MnCO3, FeC2O4, and (NH4)H2PO4 in H2O containing HNO3 and citric acid (800 °C, 30 min).
ChemInform Abstract: Luminescence of Complex Ion WO18‐12 in Dy3+ Doped Nanocrystal Gd6WO12 Phosphor.
Authors: Yu Tingting , Sun Jiashi , Hua Ruinian , Cheng Lihong , Zhong Haiyang , Li Xiangping , Yu Hongquan , Chen Baojiu 
Published: December 2010

AbstractNanocrystalline Gd6WO12:Dy3+ phosphor is synthesized by coprecipitation from an aqueous solution of GdCl3, DyCl3 (molar ratio of 99:1), and Na2WO4 (pH < 12 adjusted with NH3, 30 min) followed by calcination at 900 °C for 4 h.
ChemInform Abstract: Fabrication of Apatite‐Type La9.33(SiO4)6O2 Hollow Nanoshells as Energy‐Saving Oxidative Catalysts.
Authors: Zhang Xian‐Hua , Yi Xiaodong , Zhang Jiawei , Xie Zhaoxiong , Kang Junyong , Zheng Lansun 
Published: December 2010

AbstractApatite‐type La9.33(SiO4)6O2 hollow nanoshells are prepared from an aqueous solution of La(NO3)3, trisodium citrate, and urea (autoclave, 200 °C, 8 h) followed by dispersion of the obtained precipitate in aqueous NH4OH and addition of EtOH and Si(OEt)4 (10 h).
ChemInform Abstract: High‐Pressure Synthesis and Characterization of the Fluoride Borate Tm5(BO3)2F9.
Authors: Haberer Almut , Enders Michael , Kaindl Reinhard , Huppertz Hubert 
Published: December 2010

AbstractSingle crystals of the title compound are obtained from a stoichiometric mixture of B2O3, Tm2O3, and TmF3 (BN crucible, 5 GPa, 900 °C, 20 min).
ChemInform Abstract: Yb3O(OH)6Cl·2H2O: An Anion‐Exchangeable Hydroxide with a Cationic Inorganic Framework Structure.
Authors: Goulding Helen V. , Hulse Sarah E. , Clegg William , Harrington Ross W. , Playford Helen Y. , Walton Richard I. , Fogg Andrew M. 
Published: December 2010

AbstractThe title compound is hydrothermally synthesized from an aqueous solution of YbCl3, NaCl, and NaOH (autoclave, 220 °C, 14 h).
ChemInform Abstract: Binary Bismuth(III) Azides: Bi(N3)3, [Bi(N3)4]‐, and [Bi(N3)6]3‐.
Authors: Villinger Akexander , Schulz Axel 
Published: December 2010

AbstractCompounds (II) and (III) are characterized by IR and Raman spectroscopy, and compounds (IV), (V), and (VII) by single crystal XRD, 14N NMR, IR, and Raman spectroscopy.
ChemInform Abstract: Synthesis, High‐Resolution Crystal Structure Refinement and Magnetic Properties of the Manganese‐Rich Cementite‐Type Mn1.8Fe1.2C.
Authors: Stork Ludwig , Mueller Paul , Speldrich Manfred , Koegerler Paul , von Appen Joerg , Dronskowski Richard 
Published: December 2010

AbstractThe title compound is obtained from the elements in almost quantitative yield (1030 °C, 24 h; quenching).
ChemInform Abstract: Development of an Icosahedral Quasicrystal and Two Approximants in the Ca—Au—Sn System: Syntheses and Structural Analyses.
Authors: Lin Qisheng , Corbett John D. 
Published: December 2010

AbstractThe icosahedral quasicrystal Ca15Au60Sn25 (I) and the corresponding 1/1 and 2/1 approximants Ca3Au14.36Sn4.38 (II) and Ca13Au47.2Sn28.1 (III), resp., are prepared from Ca/Au/Sn mixtures (850 °C, 24 h) in the ratio of 14.5/60.1/25.4 for (I) (quenching, 90% yield), 13/67/20 for (II) (annealing at 500 °C for three weeks, 90% yield), and 15/52.5/32.5 for (III) (annealing at 400 °C for three weeks, <95% yield).
ChemInform Abstract: Monofluorinated Aziridines in Asymmetric Synthesis of Chiral Fluorinated Prop‐2‐yn‐1‐amines.
Authors: Konev A. S. , Tehrani K. Abbaspour , Khlebnikov A. F. , Novikov M. S. , Magull J. 
Published: December 2010

AbstractEnantioenriched fluorinated aziridines (III), obtained by aziridination of imines (I) with fluorocarbene, undergo aziridine ring opening in the presence of potassium alkynyltrifluoroborates (V) to give optically active fluorinated ynamines (VI)/(VII).
ChemInform Abstract: Solvent‐Free Direct Enantioselective Aldol Reaction Using Polystyrene‐Supported N‐Sulfonyl‐(Ra)‐binam‐D‐prolinamide as a Catalyst.
Authors: Banon‐Caballero Abraham , Guillena Gabriela , Najera Carmen 
Published: December 2010

AbstractPolystyrene‐supported binam‐prolinamide (PSBP) is used as catalyst in the aldol reaction between several ketones and aldehydes under solvent‐free or aqueous conditions affording the corresponding aldol product in high regio‐, diastereo, and enantioselectivities.
ChemInform Abstract: Electron‐Donating and Rigid P‐Stereogenic Bisphospholane Ligands for Highly Enantioselective Rhodium‐Catalyzed Asymmetric Hydrogenations.
Authors: Zhang Xiaowei , Huang Kexuan , Hou Guohua , Cao Bonan , Zhang Xumu 
Published: December 2010

AbstractThe new P‐stereogenic bisphospholane ligand (ZPHOS) shows high effectivity in the rhodium‐catalyzed hydrogenation of various functionalized olefins.
ChemInform Abstract: Palladium/Tris(tert‐butyl)phosphine‐Catalyzed Suzuki Cross‐Couplings in the Presence of Water.
Authors: Lou Sha , Fu Gregory C. 
Published: December 2010

AbstractCommercially available KF·2H2O is used instead of anhydrous KF as inexpensive activator for the title reaction of aryl, heteroaryl, and alkenyl halides and boronic acids.
ChemInform Abstract: Polystyrene‐Supported Amino Acids as Efficient Catalyst for Chemical Fixation of Carbon Dioxide.
Authors: Qi Chaorong , Ye Jinwu , Zeng Wei , Jiang Huanfeng 
Published: December 2010

AbstractDioxolanones and oxazolidinones are prepared by treatment of epoxides or aziridines, respectively, with CO2 under neat conditions in the presence of only 0.6 mol% of polymer‐supported threonine or tyrosine.
ChemInform Abstract: Improved Microwave‐Assisted Ring Opening of 1,1,1‐Trifluoro‐2,3‐epoxypropane: Synthesis of New 3‐Alkoxy‐1,1,1‐trifluoropropan‐2‐ols.
Authors: Rayo Josep , Munoz Lourdes , Rosell Gloria , Bosch Ma. Pilar , Guerrero Angel 
Published: December 2010

AbstractThe products are of interest as subunits of polyfunctional bioactive molecules and as synthons of liquid crystalline molecules.
ChemInform Abstract: Asymmetric Synthesis of Functionalized, Monocyclic Chlorocyclobutenes.
Authors: Darses Benjamin , Greene Andrew E. , Poisson Jean‐Francois 
Published: December 2010

AbstractPolyfunctional monocyclic chiral chlorocyclobutenes are constructed starting from the chiral stericol‐derived enol ethers and trichloroacetyl chloride.
ChemInform Abstract: Organocatalytic Asymmetric Inverse‐Electron‐Demand Diels—Alder Reaction of Electron‐Deficient Dienes and Crotonaldehyde.
Authors: Li Jun‐Long , Kang Tai‐Ran , Zhou Si‐Li , Li Rui , Wu Li , Chen Ying‐Chun 
Published: December 2010

AbstractThe present first organocatalytic asymmetric inverse‐electron‐demand Diels—Alder reaction of electron‐deficient dienes with crotonaldehyde gives cyclohexene derivatives with high diastereo‐ and enantioselectivity.
ChemInform Abstract: Heck Reaction Catalyzed by a Recyclable Palladium Supported on Shell Powder.
Authors: Shen Yong‐Miao , Du Yi‐Jun , Zeng Min‐Feng , Zhi Duo , Zhao Sheng‐Xian , Rong Lin‐Mei , Lv Shao‐Qin , Du Lin , Qi Chen‐Ze 
Published: December 2010

AbstractA novel palladium catalyst supported on shell powder is prepared to be used in Heck reactions of various aryl iodides with olefins.
ChemInform Abstract: A General Palladium‐Catalyzed Sonogashira Coupling of Aryl and Heteroaryl Tosylates.
Authors: R'kyek Omar , Halland Nis , Lindenschmidt Andreas , Alonso Jorge , Lindemann Peter , Urmann Matthias , Nazare Marc 
Published: December 2010

AbstractThe present new general palladium‐catalyzed procedure for the cross‐coupling of (hetero)aryl tosylates provides a facile access to various functionalized (hetero)aryl alkynes tolerating many functional groups.
ChemInform Abstract: Formamidines — Versatile Ligands for Zinc‐Catalyzed Hydrosilylation and Iron‐Catalyzed Epoxidation Reactions.
Authors: Enthaler Stephan , Schroeder Kristin , Inoue Shigeyoshi , Eckhardt Bjoern , Junge Kathrin , Beller Matthias , Driess Matthias 
Published: December 2010

AbstractFormamidine ligands, e.g. (I), are successfully applied in the Zn‐catalyzed hydrosilylation—hydrolysis reaction of a diversity of aromatic and aliphatic ketones [cf.
ChemInform Abstract: A Selective and Benign Synthesis of Functionalized Benzalacetones via Mizoroki—Heck Reaction Using Aryldiazonium Salts.
Authors: Stern Therese , Rueckbrod Sven , Czekelius Constantin , Donner Constanze , Brunner Heiko 
Published: December 2010

AbstractEither Pd(OAc)2 or Pd‐C clusters generated by pre‐reduction of Pd(OAc)2 with MeOH in the presence of charcoal before starting the reaction are used as catalysts in the presence of CaCO3 as base.
ChemInform Abstract: Unexpected Reduction of N‐Hydroxyphthalimides to Phthalimides — Orthogonal Reduction of Functionalized N‐Hydroxyphthalimides.
Authors: Jacq Jerome , Berthiol Florian , Einhorn Cathy , Einhorn Jacques 
Published: December 2010

AbstractSince the attempt to borylate starting compound (I) at the iodo function fails and loss of the N‐hydroxy group is observed instead, the conditions are optimized and applied to the reduction of various N‐hydroxyphthalimide derivatives.
ChemInform Abstract: Chiral Phosphoric Acid Catalyzed Peroxidation of Imines.
Authors: Zheng Wenhua , Wojtas Lukasz , Antilla Jon C. 
Published: December 2010

AbstractThe title reaction provides direct access to α‐amino peroxides with high enantioselectivity using the phosphoric acid catalyst CPAB which activates both the nucleophile and electrophile by hydrogen‐bonding interactions.
ChemInform Abstract: TAPC‐Promoted Oxidation of Sulfides and Deoxygenation of Sulfoxides.
Authors: Bahrami Kiumars , Khodaei Mohammad M. , Arabi Mehdi Sheikh 
Published: December 2010

AbstractTreatment of sulfides with H2O2 and TAPC allows rapid, efficient, and selective access to either sulfoxides or sulfones.
ChemInform Abstract: A Novel Synthesis of N‐Unsubstituted β‐Enamino Thioesters from 3‐Arylisoxazoles and 3‐Aryl‐5‐phenylthio‐2‐isoxazolines.
Authors: Vitale Paola , Di Nunno Leonardo , Scilimati Antonio 
Published: December 2010

AbstractThe base‐mediated conversion of isoxazolines (I) and isoxazoles (III) into target compounds (II) is accompanied by the formation of several side products.
ChemInform Abstract: Zinc Chloride Enhanced Arylations of Secondary Benzyl Trifluoroacetates in the Presence of β‐Hydrogen Atoms.
Authors: Duan Hui , Meng Lingkui , Bao Denghui , Zhang Heng , Li Yao , Lei Aiwen 
Published: December 2010

AbstractArylation of benzyl trifluoroacetates with arylzinc reagents proceeds in the presence of β‐hydrogen atoms under mild conditions without any palladium catalysts.
ChemInform Abstract: Periselectivity Switch of Acylketenes in Cycloadditions with 1‐Azadienes: Microwave‐Assisted Diastereoselective Domino Three‐Component Synthesis of α‐Spiro‐δ‐lactams.
Authors: Presset Marc , Coquerel Yoann , Rodriguez Jean 
Published: December 2010

AbstractA variety of α‐spiro‐δ‐lactams is prepared selectively via an imination/Wolff rearrangement/[4 + 2]‐cycloaddition sequence.
ChemInform Abstract: Efficient Catalytic Corey—Chaykovsky Reactions Involving Ketone Substrates.
Authors: Kavanagh Sarah A. , Piccinini Alessandro , Connon Stephen J. 
Published: December 2010

AbstractAromatic and aliphatic ketones are converted into terminal epoxides by treatment with methyl triflate in the presence of tetrahydrothiophene as catalyst and a phosphazene base.
ChemInform Abstract: Pd(II)‐Catalyzed Hydroxyl‐Directed C—H Activation/C—O Cyclization: Expedient Construction of Dihydrobenzofurans.
Authors: Wang Xisheng , Lu Yi , Dai Hui‐Xiong , Yu Jin‐Quan 
Published: December 2010

AbstractIntramolecular cyclization of tertiary phenylethanol derivatives, e.g. (I), (III) or (V), proceeds smoothly in the presence of Pd(II) catalyst and Ph‐I(O‐Ac)2 to give dihydrobenzofuran derivatives in good yields.
ChemInform Abstract: A Concise Silylamine Approach to 2‐Amino‐3‐hydroxy‐indoles with Potent in vivo Antimalaria Activity.
Authors: Urgaonkar Sameer , Cortese Joseph F. , Barker Robert H. , Cromwell Mandy , Serrano Adelfa E. , Wirth Dyann F. , Clardy Jon , Mazitschek Ralph 
Published: December 2010

AbstractThe target compounds are prepared from isatins in two steps by using tert‐butyldimethylsilyl amine as an ammonia equivalent.
ChemInform Abstract: Synthesis of 3,3‐Diindolyl Oxyindoles Efficiently Catalyzed by FeCl3 and Their in vitro Evaluation for Anticancer Activity.
Authors: Kamal Ahmed , Srikanth Y. V. V. , Khan M. Naseer A. , Shaik Thokhir Basha , Ashraf Md. 
Published: December 2010

AbstractCompound (IIIb) exhibits potent cytotoxicity against SK‐N‐SH and DU‐145 human cancer cell lines, whereas compounds (IIIc)—(IIIe) and (Vc) exhibit potent cytotoxicity against the DU‐145 cell line.
ChemInform Abstract: Copper(II) Chloride Catalyzed Friedel—Crafts‐Type Conjugate Addition of Indoles to α,β‐Unsaturated Enones: Synthesis of 3‐Substituted Indoles.
Authors: Kanwar Deepika , Rani Rashmi , Agarwal Jyoti , Peddinti Rama Krishna 
Published: December 2010

AbstractThe substitution occurs exclusively at the 3‐position of indoles and N‐alkylation products are not observed.
ChemInform Abstract: Palladium‐Catalyzed Double Carbonylation Reactions of o‐Dihaloarenes with Amines in Phosphonium Salt Ionic Liquids.
Authors: Cao Hong , Alper Howard 
Published: December 2010

AbstractN‐Substituted phthalimides are prepared in phosphonium salt ionic liquid CYPHOSIL 102 as a solvent.
ChemInform Abstract: Synthesis of 2‐Aminobenzothiazole via FeCl3‐Catalyzed Tandem Reaction of 2‐Iodoaniline with Isothiocyanate in Water.
Authors: Ding Qiuping , Cao Banpeng , Liu Xianjin , Zong Zhenzhen , Peng Yi‐Yuan 
Published: December 2010

AbstractAn environmentally benign, efficient, and general route for the synthesis of 2‐aminobenzothiazole derivatives is developed.
ChemInform Abstract: Hypervalent Iodine(III) Mediated Synthesis of Novel Unsymmetrical 2,5‐Disubstituted 1,3,4‐Oxadiazoles as Antibacterial and Antifungal Agents.
Authors: Prakash Om , Kumar Manoj , Kumar Rajesh , Sharma Chetan , Aneja K. R. 
Published: December 2010

AbstractA series of 11 title compounds of type (IV) is evaluated for their antibacterial and antifungal activities.
ChemInform Abstract: Synthesis and Biological Property of Some Novel 1,3,4‐Oxadiazoles.
Authors: Ramaprasad G. C. , Kalluraya Balakrishna , Kumar B. Sunil , Hunnur Ravindra K. 
Published: December 2010

AbstractNewly synthesized oxadiazoles (VI) and (VII) are screened for biological activities.
ChemInform Abstract: A Simple Method for the Synthesis of Functionalized 6‐Aryl‐6H‐dibenzo[b,d]pyran Derivatives from 3‐Nitro‐2H‐chromenes.
Authors: Li Ping , Luo Ling‐Ling , Li Xin‐Sheng , Xie Jian‐Wu 
Published: December 2010

AbstractA domino vinylogous Michael addition—cyclization reaction of nitrochromenes (I) and (VI) with α,α‐dicyanoolefins is readily achieved in the presence of base Et3N to give functionalized dibenzopyran derivatives in moderate yields.
ChemInform Abstract: Synthesis of 3‐Amino‐2,2‐dimethyl‐8‐thia‐1‐azaspiro[4.5]decane.
Authors: Mai Wenpeng , Green Sarah A. , Bates Dallas K. , Fang Shiyue 
Published: December 2010

AbstractKey steps in the synthesis of the title compound (VII) are the prenyl‐group introduction and a iodine‐initiated aminocyclization to form the azaspirocycle.
ChemInform Abstract: One‐Pot Synthesis of Quinoline Derivatives Directly from Terminal Alkynes via Sequential Ruthenium(II) and Acid Catalysis.
Authors: Zhang Min , Roisnel Thierry , Dixneuf Pierre H. 
Published: December 2010

AbstractThe method is based on the head‐to‐head oxidative coupling of terminal alkynes to give allylic ketones, which undergo a cyclization with aniline derivatives to give the target quinolines.
ChemInform Abstract: Synthesis and Antimicrobial Activity of 1‐Alkyl and Aryl‐3‐(2‐methyl‐1,8‐naphthyridin‐3‐yl)ureas.
Authors: Ramesh D. , Chary M. Thirumala , Laxminarayana E. , Sreenivasulu B. 
Published: December 2010

AbstractCurtius rearrangement of azides (II) leads to title naphthyridin‐3‐yl ureas (IV) which are screened for antifungal activity against Alternaria alternata, Fusarium oxysporum, and Curvularia lunata.
ChemInform Abstract: Refinement of the Pharmacophore of 3,4‐Dihydroquinazoline‐2(1H)‐thiones for Their anti‐Melanogenesis Activity.
Authors: Thanigaimalai Pillaiyar , Sharma Vinay K. , Lee Ki‐Cheul , Yun Cheong‐Yong , Kim Youngsoo , Jung Sang‐Hun 
Published: December 2010

AbstractIn order to define structural requirements, novel quinazolines, e.g. (IV), are synthesized and their anti‐melanogenesis activity is evaluated using melanoma B16 cells under the stimulant of α‐MSH.
ChemInform Abstract: An Efficient Synthesis of E‐2‐Amino‐4‐aryl‐8‐(arylmethylene)‐5,6,7,8‐tetrahydrobenzo [d]pyrimidines and Their Lower Analogues
Authors: Pal Rammohan , Mandal Tapas K. , Samanta Swati , Mallik Asok K. 
Published: December 2010

Abstractvia base‐mediated cyclocondensation of α,α′‐bis(arylmethylene)cycloalkanones with guanidinium chloride
ChemInform Abstract: A Simple Synthetic Approach to Unsymmetrically Substituted (γ‐Oxoalkyl)phosphine Oxides (III)
Authors: Tatarinov D. A. , Mironov V. F. , Baronova T. A. , Kostin A. A. , Buzykin B. I. 
Published: December 2010

Abstractbased on the reaction of P‐containing heterocycles (I) with Grignard reagents and subsequent hydrolysis
Do All Hemolytic Anemias That Occur After Mitral Valve Repair Require Surgical Treatment?
Authors: Gungunes Askin , Akpinar Ibrahim , Dogan Mehmet , Baser Kazim , Yildirim Ismail Safa , Haznedaroglu Ibrahim C. 
Published: December 2010

AbstractWe report on a 29‐year‐old woman with severe hemolytic anemia following mitral valve annuloplasty. Although hemolysis due to mechanical prosthetic mitral valve is well recognized, hemolytic anemia associated with mitral valve repair is an uncommon condition. Reoperation may be considered if the patient has serious and persistent anemia. Although valve replacement is suggested to be a unique intervention, it may not be the solution every time because of mechanical effects. Various mechanisms of hemolysis related to mitral valve repair were suggested, but sufficient and precise data is not available. In this case, we tried to emphasize whether all hemolytic anemias that occur after mitral valve repair require surgical treatment. Copyright © 2010 Wiley Periodicals, Inc.
Frequency, Risk Factors, and Effect on Long‐Term Survival of Increased Troponin I Following Uncomplicated Elective Percutaneous Coronary Intervention
Authors: Loeb Henry S. , Liu Jayson C. 
Published: December 2010

AbstractBackgroundThe frequency, risk factors for, and effect on long‐term survival of increased troponin I (cTnI) following elective, uncomplicated percutaneous coronary intervention (PCI) remains uncertain.MethodsWe studied 907 patients undergoing elective PCI without recognized PCI complications and with at least 1 measurement of cTnI 12 or more h following the procedure. Patients with pre‐PCI cTnI above 0.1 ng/ml or with myocardial infarction within the previous 48 h were excluded.ResultsMaximal cTnI (TrMX) following PCI averaged 0.8 ng/ml, exceeded the upper normal of 0.1 ng/ml in 65.2% of patients and was 1.5 ng/ml or above in 13.7%. Of several demographic and procedural variables examined, the only significant predictor of TrMX was the number of stents deployed. (p < 0.0023 95% confidence interval [CI]: 0.10–0.46). Significant univariate predictors of survival (Kaplan‐Meier) were older age (p < 0.0001), diabetes (p = 0.02), peripheral vascular disease (p < 0.0001), obstructive lung disease (p < 0.0001), congestive failure (p < 0.0001), renal impairment (p < 0.0001), and TrMX of 3.62 ng/ml or above (p = 0.0451). Independent predictors (Cox) were older age (p < 0.0001), obstructive lung disease (p < 0.0001), congestive failure (p < 0.0001), and TrMX (p = 0.0272).ConclusionsElevation of cTnI occurs in most patients undergoing elective, uncomplicated PCI. Deployment of multiple stents is associated with higher values of cTnI. Long‐term survival is primarily influenced by age and pre‐PCI comorbidities, however patients with the highest values of cTnI after PCI are also at increased risk of reduced survival. Significant independent predictors of reduced survival were older age, obstructive pulmonary disease, congestive failure (p < 0.0001 for each), and maximal post‐PCI cTnI (p = 0.0272). Copyright © 2010 Wiley Periodicals, Inc.