bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation and economic analysis of fermented fish viscera silage in diets for tambaqui (Colossoma macropomum) and its effects on the physical quality of pellets, growth performance, health parameters
Authors: Santana Thiago M. , Dantas Francisco M. , Prestes Armando G. , Jerônimo Gabriela T. , da Costa Jesaias I. , dos Santos Driely K. M. , Pastrana Yugo M. , Yamamoto Fernando Y. , Gonçalves Ligia U. 
Published: June 2024

AbstractThe production of silage using fish viscera can be carried out with straightforward methods and permits the exploitation of nutrients that are usually discarded. This process fosters the concept of circular aquaculture. The aim of this study was to evaluate the inclusion of increasing levels of fish viscera silage (VS) on the physical quality of the feed pellets and their effects on their growth performance, health parameters and on economic indices when the experimental extruded feed was offered to tambaqui. A fermented fish VS produced in‐house was included in increasing levels on a wet‐basis in the formulation of five experimental diets (VS 0%, VS 5%; VS 10%; VS 15% and VS 20%). Juvenile tambaqui (~22.6 g) were stocked in fibreglass tanks of 700 L (n = 4; 21 fish per tank) with a recirculation system and the five experimental diets were attributed in a completely randomized design. The fish were fed with the experimental diets (to apparent satiation) for 13 weeks. At the end of the trial, no significant differences were observed for production performance. Fish fed with the highest inclusion level of VS presented the highest concentration of plasma cholesterol, but this was still within acceptable values for this species. The inclusion of fish VS in diets for juvenile tambaqui reduced the activity of the plasma ALT enzyme, confirming normal liver function. Extruded feed containing fish VS had a production cost of US$ 0.95 per kg, which does not significantly impact the economic indices. Up to 20% of fish VS can be included in the extruded feed formulation for juvenile tambaqui without impairing growth performance or affecting health parameters.
Population genomics resolves cryptic species of the ecologically flexible genus Laspinema (Cyanobacteria)
Authors: Dvořák Petr , Skoupý Svatopluk , Jarošová Hana , Páleníčková Kateřina , Stanojković Aleksandar 
Published: June 2024

AbstractCyanobacterial taxonomy is entering the genomic era, but only a few taxonomic studies have employed population genomics, which provides a framework and a multitude of tools to understand species boundaries. Phylogenomic and population genomic analyses previously suggested that several cryptic lineages emerged within the genus Laspinema. Here, we apply population genomics to define boundaries between these lineages and propose two new cryptic species, Laspinema olomoucense and L. palackyanum. Moreover, we sampled soil and puddles across Central Europe and sequenced the 16S rRNA gene and 16S‐23S ITS region of the isolated Laspinema strains. Together with database mining of 16S rRNA gene sequences, we determined that the genus Laspinema has a cosmopolitan distribution and inhabits a wide variety of habitats, including freshwater, saline water, mangroves, soil crusts, soils, puddles, and the human body.
Using Large‐Scale Location Data to Examine Racial Diversity and Segregation in Church Attendees’ Home Neighborhoods
Authors: Greenberg Pierce , Danielsen Sabrina , Wishart Ryan 
Published: June 2024

AbstractThe racial diversity of churches has been a longstanding topic of interest in the social science of religion. Studies have historically found low levels of racial diversity within churches—but some evidence suggests that diversification is increasing. However, past research has not addressed racial segregation in another significant setting: church attendees’ home neighborhoods. Our article illustrates how large‐scale location data collected from smartphones can estimate the average racial demographics of where church attendees live. Our findings show that church attendees in Omaha, Nebraska—especially those attending Evangelical Protestant, Roman Catholic, and Mainline Protestant churches—live in more homogenously white census blocks than the average census block in the city.
A promoter polymorphism defines distinct roles in anther development for Col‐0 and Ler‐0 alleles of Arabidopsis ACYL‐COA BINDING PROTEIN3
Authors: Guo Ze‐Hua , Hu Tai‐Hua , Hamdan Mohd Fadhli , Li Minghui , Wang Ruifeng , Xu Jie , Lung Shiu‐Cheung , Liang Wanqi , Shi Jianxin , Zhang Dabing , Chye Mee‐Len 
Published: June 2024

Summary

Acyl‐CoA‐Binding Proteins (ACBPs) bind acyl‐CoA esters and function in lipid metabolism. Although acbp3‐1, the ACBP3 mutant in Arabidopsis thaliana ecotype Col‐0, displays normal floral development, the acbp3‐2 mutant from ecotype Ler‐0 characterized herein exhibits defective adaxial anther lobes and improper sporocyte formation.

To understand these differences and identify the role of ERECTA in ACBP3 function, the acbp3 mutants and acbp3‐erecta (er) lines were analyzed by microscopy for anther morphology and high‐performance liquid chromatography for lipid composition.

Defects in Landsberg anther development were related to the ERECTA‐mediated pathway because the progenies of acbp3‐2 × La‐0 and acbp3‐1 × er‐1 in Col‐0 showed normal anthers, contrasting to that of acbp3‐2 in Ler‐0. Polymorphism in the regulatory region of ACBP3 enabled its function in anther development in Ler‐0 but not Col‐0 which harbored an AT‐repeat insertion. ACBP3 expression and anther development in acbp3‐2 were restored using ACBP3pro (Ler)::ACBP3 not ACBP3pro (Col)::ACBP3. SPOROCYTELESS (SPL), a sporocyte formation regulator activated ACBP3 transcription in Ler‐0 but not Col‐0.

For anther development, the ERECTA‐related role of ACBP3 is required in Ler‐0, but not Col‐0. The disrupted promoter regulatory region for SPL binding in Col‐0 eliminates the role of ACBP3 in anther development.
Urban resilience governance mechanism: Insights from COVID‐19 prevention and control in 30 Chinese cities
Authors: Xia Cao , Delei Wang 
Published: June 2024

AbstractDue to the pervasive uncertainty in human society, super large and megacities are increasingly prone to becoming high‐risk areas. However, the construction of urban resilience in this new era lacks sufficient research on the core conditions and complex interactive mechanisms governing it. Hence, this study proposes a specialized event‐oriented framework for governing urban resilience in China based on the pressure‐state‐response (PSR) theory. We examined COVID‐19 cases in 30 cities across China and analyzed the distribution of prevention and control achievements between high‐level and non‐high‐level conditions. Our findings reveal the following key points: (1) High‐level achievements in COVID‐19 prevention and control rely on three condition configurations: non‐pressure‐responsive type, pressure‐state type, and pressure‐responsive type. (2) High economic resilience may indicate a robust state of urban systems amid demographic pressures. In cities experiencing fewer event pressure factors, the application of digital technology plays a crucial role in daily urban management. (3) The implementation of flexible policies proves beneficial in mitigating the impact of objective pressure conditions, such as environmental factors, on urban resilience.
Use of a free proximal ulnar autograft for ipsilateral radial lengthening in a dog with a short radius and subsequent elbow incongruity
Authors: Sevy Julia J. , Bevan John 
Published: June 2024

AbstractObjectiveTo report the technique and outcome of proximal ulnar autograft transplantation to achieve ipsilateral radial lengthening in a dog with premature closure of both proximal and distal radial physes.Study designCase report.AnimalsAn 8‐month‐old female spayed Border Collie.MethodsThe dog was presented for a grade III/IV left thoracic limb lameness localized to the elbow. Orthogonal radiographs of both forelimbs revealed a 7% length deficit of the left radius and elbow subluxation indices indicative of left elbow incongruity due to suspect premature closure of both radial physes. Radial lengthening consisted of a proximal ulnar ostectomy, a radial osteotomy, and transplantation of the ulnar autograft into the radial osteotomy site secured with an eight‐hole dynamic compression plate. Orthopedic examinations were conducted at 2 weeks, 4 weeks, and 3 years postoperatively. Radiographic examinations were completed preoperatively, immediately postoperatively, and at 4 weeks and 3 years postoperatively.ResultsLameness improved with a grade II/IV lameness at 4 weeks postoperatively and complete resolution at 3 years postoperatively. Radiographic examination at 4 weeks showed persistent radial lengthening of 1 cm, and a decreased humeroradial index (HRI), humeroulnar index (HUI), and radioulnar index (RUI) compared with preoperative values. At the 3 year examination, the HRI and HUI had increased indicating progression of elbow incongruity. The patient remained clinically unaffected.ConclusionIn dogs with radial shortening and elbow incongruity, use of an ipsilateral proximal ulnar autograft with rigid internal fixation can be an effective treatment for radial lengthening to improve elbow congruity and resolve lameness.
Scalar Field Prediction on Meshes Using Interpolated Multiresolution Convolutional Neural Networks
Authors: Ferguson Kevin , Gillman Andrew , Hardin James , Kara Levent Burak 
Published: June 2024

Abstract
Scalar fields, such as stress or temperature fields, are often calculated in shape optimization and design problems in engineering. For complex problems where shapes have varying topology and cannot be parametrized, data-driven scalar field prediction can be faster than traditional finite element methods. However, current data-driven techniques to predict scalar fields are limited to a fixed grid domain, instead of arbitrary mesh structures. In this work, we propose a method to predict scalar fields on arbitrary meshes. It uses a convolutional neural network whose feature maps at multiple resolutions are interpolated to node positions before being fed into a multilayer perceptron to predict solutions to partial differential equations at mesh nodes. The model is trained on finite element von Mises stress fields, and once trained, it can estimate stress values at each node on any input mesh. Two shape datasets are investigated, and the model has strong performance on both, with a median R2 value of 0.91. We also demonstrate the model on a temperature field in a heat conduction problem, where its predictions have a median R2 value of 0.99. Our method provides a potential flexible alternative to finite element analysis in engineering design contexts. Code and datasets are available online.
Stability Analysis of Pure Oil-Water Emulsion in Gravity-Based Separators
Authors: Alanazi K. , Mohan R. , Kolla S. S. , Shoham O. 
Published: June 2024

Abstract
The purpose of this work is to investigate the stability of pure (emulsifier-free) oil-water emulsion in a gravity-based separator as a function of various parameters such as mixing speed, water volume concentration, temperature, and appearance. Only simple fluids (ExxsolTMD110 and distilled water) were used to form the dispersion in a separator of operational volume 200 ml and internal diameter of 60 mm. Data were gathered from a portable dispersion characterization rig where videos of liquid phase separation can be saved and scanned. The study considered a wide range of mixing speeds between 600 rpm and 2500 rpm, with elevated temperatures of 60 °C and 80 °C. Both types (oil-in-water (O/W) and water-in-oil (W/O)) of pure emulsion were studied. In addition, two volumetric water concentrations (WCs) were considered for each type to investigate its stability under the parameters tested (i.e., 25% and 50% WC for W/O emulsion and 75% and 90% WC for O/W emulsion). The stability of the emulsion was examined in terms of the separation profiles of the water and oil phase, oil/water mixture volume, initiation time of free phase separation and/or the final time of separation. Mixing speed was shown to drastically impact the stability of O/W emulsion, from a few minutes to over 4 h. Conversely, insignificant effects of mixing speed were seen for W/O emulsion as the emulsions overall separated in a few seconds. Although temperature accelerated the oil separation rates of 75% WC emulsions, it delayed the initiation time of water separation.
Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication
Authors: Biswas Banhi , Lai Kin Kui , Bracey Harrison , Datta Siddhartha A. K. , Harvin Demetria , Sowd Gregory A. , Aiken Christopher , Rein Alan 
Published: June 2024

ABSTRACT

We have investigated the function of inositol hexakisphosphate (IP6) and inositol pentakisphosphate (IP5) in the replication of murine leukemia virus (MLV). While IP6 is known to be critical for the life cycle of HIV-1, its significance in MLV remains unexplored. We find that IP6 is indeed important for MLV replication. It significantly enhances endogenous reverse transcription (ERT) in MLV. Additionally, a pelleting-based assay reveals that IP6 can stabilize MLV cores, thereby facilitating ERT. We find that IP5 and IP6 are packaged in MLV particles. However, unlike HIV-1, MLV depends upon the presence of IP6 and IP5 in target cells for successful infection. This IP6/5 requirement for infection is reflected in impaired reverse transcription observed in IP6/5-deficient cell lines. In summary, our findings demonstrate the importance of capsid stabilization by IP6/5 in the replication of diverse retroviruses; we suggest possible reasons for the differences from HIV-1 that we observed in MLV.

IMPORTANCE
Inositol hexakisphosphate (IP6) is crucial for the assembly and replication of HIV-1. IP6 is packaged in HIV-1 particles and stabilizes the viral core enabling it to synthesize viral DNA early in viral infection. While its importance for HIV-1 is well established, its significance for other retroviruses is unknown. Here we report the role of IP6 in the gammaretrovirus, murine leukemia virus (MLV). We found that like HIV-1, MLV packages IP6, and as in HIV-1, IP6 stabilizes the MLV core thus promoting reverse transcription. Interestingly, we discovered a key difference in the role of IP6 in MLV versus HIV-1: while HIV-1 is not dependent upon IP6 levels in target cells, MLV replication is significantly reduced in IP6-deficient cell lines. We suggest that this difference in IP6 requirements reflects key differences between HIV-1 and MLV replication.
Impact of first pass effect in endovascular treatment of large core stroke: a post-hoc analysis of the ANGEL-ASPECT trial
Authors: Huang Xianjun , Sun Dapeng , Nguyen Thanh N , Pan Yuesong , Wang Mengxing , Abdalkader Mohamad , Zaidat Osama O , Ma Ning , Gao Feng , Mo Dapeng , Miao Zhongrong , Huo Xiaochuan , Zhou Zhiming 
Published: June 2024

BackgroundThe first-pass effect (FPE) is linked to better safety and efficacy prognosis in patients with small- to- moderate sized ischemic infarctions. We evaluated the incidence, prognosis, and predictors of FPE in patients with large core infarctions (LCIs).MethodsWe conducted a post-hoc analysis of data from the Trial of Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients with a Large Infarct Core (ANGEL-ASPECT). The FPE was defined as a successful recanalization (expanded Thrombolysis in Cerebral Infarction (eTICI) 2 c/3, and eTICI 2b-3 as modified FPE (mFPE)) after one pass. The primary outcome was clinical functional independence, and the secondary outcomes were independent ambulation, assessed by the modified Rankin Scale (mRS) at 90 days. Safety outcomes included symptomatic intracranial hemorrhage (sICH) defined by the Heidelberg bleeding classification, any intracranial hemorrhage (ICH), and death within 90 days of stroke onset.ResultsOf the 226 patients in the study, FPE and mFPE were achieved in 33 (14.6%) and 82 (36.3%) patients, respectively. Patients with FPE exhibited shorter onset-to-puncture times (adjusted odds ratio [OR] 0.915; 95% confidence interval [CI]: 0.84 to 0.996), and patients with mFPE were older (OR 1.039; 95% CI: 1.005 to 1.075). mFPE was significantly associated with favorable outcomes (modified Rankin score [mRS] 0–2: OR 2.64; 95% CI: 1.37 to 5.07; mRS 0–3: OR 3.31; 95% CI: 1.73 to 6.33). FPE tended to improve outcomes (mRS 0–3: OR 2.24; 95% CI: 0.92 to 4.97; p=0.08). ICH rates (OR 0.60; 95% CI: 0.34 to 1.05; p=0.07) and 90-day deaths (OR 0.57; 95% CI: 0.30 to 1.09; p=0.09) tended to decrease in patients who achieved mFPE but not in patients who achieved FPE.ConclusionsIn the ANGEL-ASPECT trial, patients who achieved mFPE had a higher rate of independent ambulation and functional independence, and the rates of any ICH and 90-day death tended to decrease.
Tracing the footprints of MPXV in Asia: phylogenetic insights and lineage dynamics
Authors: Chen Yung-Chun , Liao Yu-Chieh , Mao Yan-Chiao , Yeh Ting-Kuang , Liu Po-Yu 
Published: June 2024

ObjectivesThe 2022 global outbreak of monkeypox virus (MPXV), previously confined to Central and West Africa, necessitates an enhanced understanding of its spread. Comprehensive genomic surveillance to understand the virus’s evolution and spread is needed, particularly in Asia.MethodsGenomic data from 169 MPXV genome sequences in Asia were analysed. Through advanced genomic sequencing of clinical samples, we analysed the distribution and mutations of MPXV lineages in Asia.ResultsPhylogenetic analysis revealed a distinct clustering of C.1 strains rise in Northeast Asia in 2023, while genomic examination identified specific consensus mutations like R84K, R665C and L16F in C.1 strains. The mutations, coupled with an increased rate of apolipoprotein B mRNA-editing catalytic polypeptide-like 3 motif G-to-A mutations in C.1 (OR 24.87±8.81), indicate a potential adaptation mechanism.ConclusionsOur findings underscore the need for ongoing surveillance and provide vital insights into MPXV’s evolving dynamics, aiding in public health strategy formulation against this emerging infectious threat.
Hepatitis C virus infection is uncommon at baseline and during follow-up among individuals using PrEP in the Dutch national PrEP programme between 2019 and 2022
Authors: Hage Kris , Boyd Anders , Op de Coul Eline L M , Sarink Danja , Hoornenborg Elske , Prins Maria 
Published: June 2024

ObjectivesStudies showed that men who have sex with men (MSM), including those using pre-exposure prophylaxis (PrEP), are at increased risk of hepatitis C virus (HCV) infection. We evaluated HCV prevalence and incidence, along with their associated determinants, in a cohort of PrEP-using individuals in the Netherlands.MethodsIn 2019, the Netherlands launched a 5-year national programme that offers subsidised PrEP to eligible individuals. We used prospectively collected data from individuals registered in this programme between 2019 and 2022. Individuals underwent annual testing for HCV antibodies and additional HCV-RNA testing when antibodies were present. We calculated the prevalence of past/current HCV infection at first visit and overall incidence rate (IR) during follow-up. Univariable logistic and Poisson regression models were used to identify determinants associated with past/current prevalent or incident HCV infection, respectively. Behavioural factors referred to those occurring in the previous 6 months.ResultsA total of 10 563 (n=10 319, 97.7% MSM) were included. At first visit, 66 of 10 563 (0.6%) had a past/current HCV infection, which was associated with older age [odds ratio (OR) per 10 years=1.57, 95% confidence interval (CI)=1.31 to 1.88], the use of PrEP before first visit (OR=3.03, 95% CI=1.79 to 5.13), receptive condomless anal sex (CAS) (OR=2.73, 95% CI=1.25 to 5.98), chemsex (OR=2.44, 95% CI=1.49 to 3.99) and injecting drug use (IDU) (OR=6.61, 95% CI=2.35 to 18.61). Among 9851 individuals contributing to 17 150 person-years (PYs) of follow-up, 64 incident HCV infections (IR=0.37 per 100 PYs, 95% CI=0.29 to 0.48) were identified. Factors associated with incident HCV infection were receptive CAS [incidence rate ratio (IRR)=2.59, 95% CI=1.12 to 6.02], chemsex (IRR=1.78, 95% CI=1.06 to 2.98), sexually transmitted infection diagnosis (IRR=2.30, 95% CI=1.23 to 4.31) and IDU (IRR=6.15, 95% CI=2.20 to 17.18).ConclusionsPast/current prevalence and incidence of HCV were low among individuals in the Dutch PrEP programme. Infections were associated with behaviour known to be associated with HCV. Instead of annual HCV testing, as stated in most PrEP care guidelines, testing frequency for HCV could be based on behaviours associated with HCV acquisition.
Testing Z boson rare decays $$Z\rightarrow H_1 \gamma , A_1 \gamma $$ with $$(g-2)_\mu ,$$ $$ M_W,$$ and $$BR(h_{\textrm{SM}}\rightarrow Z\gamma )$$ in the NMSSM
Authors: Bisal Subhadip , Das Debottam 
Published: June 2024

AbstractWe study the rare decay process of Z boson into photon, accompanied by a CP-even or CP-odd scalar. We present the analytical delineation of the processes through the model-independent parametrizations of the new physics couplings and, finally, consider the Next-to-Minimal Supersymmetric Standard Model to mark out the parameter space where the branching fraction can have the maximum value. As a part of the necessary phenomenological and experimental cross-checks, we aim to fit the anomalous magnetic moment of the muon and W boson mass anomaly through the supersymmetric contributions. We also find that the decays $$Z\rightarrow H_1 \gamma , A_1 \gamma $$

Z
→

H
1

γ
,

A
1

γ

can serve as an excellent complementary test to $$BR(h_{\textrm{SM}}\rightarrow Z\gamma ).$$

B
R
(

h
SM

→
Z
γ
)
.

In fact, to facilitate future searches, we unveil a few benchmark points that additionally satisfy the deviation of $$BR(h_{\textrm{SM}}\rightarrow Z\gamma )$$

B
R
(

h
SM

→
Z
γ
)

from the SM value based on the recent measurements of ATLAS and CMS. Future proposals such as ILC, CEPC, and FCC-ee are anticipated to operate for multiple years, focusing on center-of-mass energy near the Z pole. Consequently, these projects will be capable of conducting experiments at the Giga-Z$$(10^{9}$$

(

10
9

of Z bosons) and Tera-Z$$(10^{12}$$

(

10
12

of Z bosons) phases, which may probe the aforesaid rare decay processes, thus the model as well. These unconventional yet complementary searches offer different routes to explore the supersymmetric models with extended Higgs sectors like NMSSM.
Review of NSAID Hypersensitivity Reactions Based on Clinical Phenotyping
Authors: Leong Cheong Si , Man Chan Choi , Kan Andy Ka Chun , Li Philip Hei 
Published: June 2024

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic, antipyretic, and anti-inflammatory properties. However, they are also associated with a broad spectrum of hypersensitivity reactions, ranging from mild cutaneous manifestations to severe systemic responses. The complex nature of these reactions and their underlying mechanisms pose challenges in diagnosis and management. We review the clinical evidence to six distinct clinical phenotypes of NSAID hypersensitivity, including: NSAID-induced urticaria/angioedema or anaphylaxis (SNIUAA), NSAID-exacerbated respiratory disease (NERD), NSAID-exacerbated cutaneous disease (NECD), NSAID-induced urticaria/angioedema (NIUA), food-dependent NSAID-induced hypersensitivity reactions (FDNIH), and selective NSAID-induced delayed reactions (SNIDR). This review aims to provide a comprehensive review of NSAID hypersensitivity reactions based on clinical phenotyping, which can aid in understanding and managing these adverse events.