bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sleep arrangements and maternal adaptation in infancy
Authors: Countermine Molly S. , Teti Douglas M. 
Published: November 2010

AbstractAmong the many decisions that parents make regarding child‐rearing practices, an important one involves sleep arrangements. Little is known about the relationship between chosen sleep arrangements, parents' adaptation to these choices, parental sleep quality, spousal support, and parental distress. Forty‐five mothers and fathers with infants 1 to 24 months old completed measures of parental attitudes and practices regarding sleep arrangements. Shared sleep with one's infant was associated with poorer parental adaptation to infant sleep disruption, and this was true even when parents endorsed the practice of sharing sleep with their infants. Among mothers, shared sleep and poorer adaptation to infant sleep were significantly associated with elevated depressive symptoms, poorer sleep quality, and spousal criticism directed to mothers about where the infant slept during the night. For mothers, criticism from their spouses about where the baby slept, mothers' sleep quality, and depressive symptoms mediated the link between sleep arrangements and maternal adaptation. Results emphasize the importance of taking into account individual differences in the quality of parents' adaptation to infant sleep behavior, a construct largely ignored in the child sleep literature to date, in understanding linkages between infant sleep quality and infant–parent outcomes.
In vitroandin vivobiocompatibility studies of a recombinant analogue of spidroin 1 scaffolds
Authors: Moisenovich M. M. , Pustovalova O. L. , Yu Arhipova A. , Vasiljeva T. V. , Sokolova O. S. , Bogush V. G. , Debabov V. G. , Sevastianov V. I. , Kirpichnikov M. P. , Agapov I. I. 
Published: November 2010

AbstractThe goal of this study was to generate porous scaffolds from the genetically engineered protein, an analogue ofNephila clavipesspidroin 1 (rS1/9) and to assess the properties of new rS1/9 scaffolds essential for bioengineering. The salt leaching technique was used to make the rS1/9 scaffolds of interconnected macroporous structure with spontaneously formed micropores. The tensile strength of scaffolds was 18 ± 5 N/cm2. Scaffolds were relatively stable in a phosphate buffer but degraded in oxidizing environment after 11 weeks of incubation. Applicability of the recombinant spidroin 1 as a substrate for cell culture was demonstrated by successful 3T3 cells growth on the surface of rS1/9 films (270 ± 20 cells/mm2vs. 97 ± 8 cells/mm2on the glass surface,p< 0.01). The 3T3 fibroblasts readily proliferated within the rS1/9 scaffold (from initially plated 19 ± 2 cells/mm3to 3800 ± 304 cells/mm3after 2 weeks). By this time, cells were uniformly distributed between the surface and deeper layers (27% ± 8% and 33% ± 4%, respectively;p> 0.05), whereas the initial distribution was 58% ± 7% and 11% ± 8%, respectively;p< 0.05). The rS1/9 scaffolds implanted subcutaneously into Balb/c mice were well tolerated. Over a 2‐month period, the scaffolds promoted an ingrowth ofde novoformed vascularized connective tissue elements and nerve fibers. Thus, scaffolds made of the novel recombinant spidroin 1 analogue are potentially applicable in tissue engineering. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
In Vitro characterization of low modulus linoleic acid coated strontium‐substituted hydroxyapatite containing PMMA bone cement
Authors: Lam W. M. , Pan H. B. , Fong M.K. , Cheung W. S. , Wong K. L. , Li Z. Y. , Luk K. D. K. , Chan W. K. , Wong C. T. , Yang C. , Lu W. W. 
Published: November 2010

AbstractPoly (methyl methacrylate) (PMMA) bone cement is widely used in vertebral body augmentation procedures such as vertebroplasty and balloon kyphoplasty. Filling high modulus PMMA increases the modulus of filled verterbra, increasing the risk of fracture in the adjacent vertebra. On the other hand, in porous PMMA bone cements, wear particle generation and deterioration of mechanical performance are the major drawbacks. This study adopts a new approach by utilizing linoleic acid coated strontium substituted hydroxyapatite nanoparticle (Sr‐5 HA) and linoleic acid as plasticizer reducing bone cement's modulus with minimal impact on its strength. We determined the compressive strength (UCS) and modulus (Ec), hydrophobicity, injectability, in vitro bioactivity and biocompatibility of this bone cement at different filler and linoleic acid loading. At 20 wt % Sr5‐HA incorporation, UCS and Ec were reduced from 63 ± 2 MPa, 2142 ± 129 MPa to 58 ± 2 MPa, 1785 ± 64 MPa, respectively. UCS and Ec were further reduced to 49 ± 2 MPa and 774 ± 70 MPa respectively when 15 v/v of linoleic acid was incorporated. After 7 days of incubation, pre‐osteoblast cells (MC3T3‐E1) attached on 20 wt % Sr5‐HA and 20 wt % Sr5‐HA with 15 v/v of linoleic acid group were higher (3.73 ± 0.01 × 104, 2.27 ± 0.02 × 104) than their PMMA counterpart (1.83 ± 0.04 × 104). Incorporation of Sr5‐HA with linoleic acid in monomer phase is more effective in reducing the bone cement's stiffness than Sr5‐HA alone. Combination of low stiffness and high mechanical strength gives the novel bone cement the potential for use in vertebroplasty cement applications. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2011.
A Raman and infrared spectroscopic study of Ca2+ dominant members of the mixite group from the Czech Republic
Authors: Čejka Jiří , Sejkora Jiří , Plášil Jakub , Keeffe Eloise C. , Bahfenne Silmarilly , Palmer Sara J. , Frost Ray L. 
Published: November 2010

AbstractThe minerals of the mixite group—zálesíite CaCu6[(AsO4)2(AsO3OH)(OH)6]·3H2O from abandoned uranium deposit Zálesí, Czech Republic and calciopetersite CaCu6[(PO4)2(PO3OH)(OH)6]·3H2O from a quarry near Domašov na Bystřicí, northern Moravia, Czech Republic—were studied by Raman and infrared spectroscopy. The observed bands were assigned to the stretching and bending vibrations of (AsO4)3− and (AsO3OH)2− ions in zálesíite, and (PO4)3− and (PO3OH)2− in calciopetersite, and to molecular water, hydroxyl ions, and Cu‐(O,OH) units in both minerals. OH···O hydrogen‐bond lengths in zálesíite and calciopetersite structures were calculated with Libowitzky's empirical relation. Copyright © 2010 John Wiley & Sons, Ltd.
Tip‐heating‐assisted Raman spectroscopy at elevated temperatures
Authors: Tarun Alvarado , Hayazawa Norihiko , Yano Taka‐Aki , Kawata Satoshi 
Published: November 2010

AbstractWe demonstrate tip‐heating‐assisted enhanced Raman spectroscopy to investigate the temperature dependence of the carbon nanotube G‐band with nanoscale resolution. The controllable and nanoscale heat generated at the tip apex was used to thermally perturb and characterize a small volume in a carbon nanotube sample that is precisely positioned underneath the tip. The dependence of tip enhancement with temperature was also experimentally examined, which is in good agreement with the enhancement calculated from the electromagnetic model of isolated spheroids. The technique presented may open up opportunities in the study of controlled heat‐assisted biochemical reactions and physical transformations of nanostructures. It can also be used for thermal characterization of various materials requiring site‐selective and controllable nanoscale heat source and could enable the realization of new photothermal devices. Copyright © 2010 John Wiley & Sons, Ltd.
Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells
Authors: Jerde Travis J. , Wu Zhong , Theodorescu Dan , Bushman Wade 
Published: November 2010

AbstractBACKGROUNDPhosphatase homologue of tensin (PTEN) is the most commonly mutated gene in prostate cancer. Bone morphogenetic proteins (BMPs) are known to promote differentiation and inhibit proliferation. Previously published reports from other organ systems led us to investigate a mechanistic relationship between PTEN and BMP signaling in prostate epithelial cells.METHODSWe analyzed growth rate and PTEN expression in E6, BPH‐1, and C4‐2B prostate epithelial cells treated with BMP‐4. We also treated doxacyclin‐inducible PTEN‐C4‐2B cells with BMP‐4 and doxacyclin to determine the effect of BMP on growth and PTEN expression in conditions of increasing PTEN expression. We determined the dependency of BMP‐mediated growth inhibition via siRNA knockdown of PTEN expression and BMP treatment. We determined PTEN protein stability by determining the effect of BMP‐4 on PTEN protein at time points after treatment with cyclohexamide, a translation inhibitor.RESULTSWe found that BMP‐4 induces PTEN in E6 and BPH‐1 cells and reduces proliferation. Knockdown of PTEN attenuated the growth‐inhibiting effects of BMP‐4 in these cells. BMP‐4 had no effect in PTEN‐negative C4‐2B cells, but doxacyclin‐driven PTEN C4‐2B cells responded to BMP‐4 with enhanced PTEN and growth inhibition. BMP‐4 also increased PTEN protein stability.CONCLUSIONSBMP signaling induces PTEN expression and sustains PTEN protein expression resulting in inhibition of prostate epithelial cell growth. These data are the first to identify a mechanistic linkage between BMP signaling and PTEN in the prostate, both of which are independently identified as tumor suppressors and suggest possible coordinate dysregulation in prostate cancer. Prostate 71:791–800, 2011. © 2010 Wiley‐Liss, Inc.
Effect of electroporation‐mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice
Authors: Goepfert Christine , Gazdhar Amiq , Frey Felix J. , Frey Brigitte M. 
Published: November 2010

AbstractBACKGROUNDCurrent therapies to treat prostate cancer are often limited. Since it has been shown that very low concentrations of diphtheria toxin A (DT‐A) result in abrogation of protein synthesis and apoptosis of cells, DT‐A might serve as an efficient killer in cancer gene therapy. For this purpose we investigated in a quantitative manner using a stereological approach the apoptotic effect of DT‐A in androgen receptor (AR) and prostate specific antigen (PSA) expressing cells after tumor formation in both flanks of SCID mice.METHODSFirst, DT‐A plasmid transfection was evaluated, using the lipid formulation DMRIE‐C in C4‐2 prostate cancer xenografts. After detection of an overall high rate of apoptosis by DMRIE‐C alone, plasmid delivery was performed in a second study by electroporation. Finally this method was used to specifically target the AR and PSA expressing cell line C4‐2 using pDT‐A driven by a prostate specific promoter and enhancer (PSE/PSA). PC‐3 cells, being AR and PSA negative, served as controls.RESULTSThe experiments revealed evidence of a reduced growth rate of AR and PSA expressing C4‐2 cells in vitro and in vivo compared to the AR and PSA negative prostate cancer cell line PC‐3. The electroporation technology favored the response compared to DMRIE‐C.CONCLUSIONThese results suggest that the local delivery of DT‐A plasmid by electroporation might present a favorable factor to treat prostate cancer. Prostate 71:872–880, 2011. © 2010 Wiley‐Liss, Inc.
Iron deficiency anaemia in pregnancy – what are the solutions?
Authors: Derbyshire Emma 
Published: November 2010

PurposeIron deficiency anaemia (IDA) is a common problem in pregnancy and may influence the health of both mother and child. The purpose of this paper is to discuss current prevention and treatment strategies for pregnancy IDA and describe alternative methods, such as food‐based approaches that may be another way forward.Design/methodology/approachA literature review was conducted to locate and summarise up‐to‐date published studies within the field.FindingsThere is good evidence that iron supplements may be used to prevent and treat IDA in pregnancy. However, there is much debate about “the optimal” dose to recommend. High doses may contribute to oxidative stress and cause gastrointestinal symptoms while there still remain problems with compliance, even for lower dose iron supplements. Encouraging the daily consumption of functional foods containing suitable levels of iron may therefore be an alternative way to improve pregnancy iron status.Research limitations/implicationsThere is a wealth of important studying the health implications of iron supplements in pregnancy. More work is needed to establish whether functional foods containing iron could be an alternative way to help improve iron status.Originality/valueMost papers and research focus on supplement use as a preventative measure and treatment for IDA; few discuss other approaches.
The impact of entrepreneurship education on succession in ethnic minority family firms
Authors: Hussain Javed G. , Scott Jonathan M. , Matlay Harry 
Published: November 2010

PurposeThe purpose of this paper is to explore the impact that entrepreneurship education can have on succession in ethnic minority family firms that operate in the highly competitive UK economy.Design/methodology/approachThe paper employs a complex conceptual model of ethnic minority graduates' economic activities and outlines the possible influence that entrepreneurship education can have on succession in their family firms. An illustrative case study is presented of an ethnic minority graduate who returned to work in the family firm.FindingsIt emerges that entrepreneurship education provision in UK HEIs is insufficiently customised to, and focused on, the specific entrepreneurial needs of graduates. Educators should take into account the complex socio‐economic and cultural differences between native and ethnic minority learning environments. Effective entrepreneurship education emerges as crucial to the survival and growth of ethnic minority family businesses in the UK and could contribute positively to ownership transfer in this type of firm.Research limitations/implicationsThe proposed theoretical model has not been empirically tested and it is only indicative of the impact that entrepreneurship education could have on succession in small ethnic minority family businesses in the UK.Originality/valueAlthough prior research has explored various aspects of ownership succession, this article focuses specifically on the impact that entrepreneurship education can have on succession in small ethnic minority family firms.
An investigation of the continuing professional development practices of Indonesian academic libraries
Authors: Maesaroh Imas , Genoni Paul 
Published: November 2010

PurposeThis paper reports on ongoing research examining the present and desired state of academic library staff education and professional development in Indonesia. The long‐term goal of the research is to determine ways in which Indonesian academic libraries and their staff can be supported in order to assist universities in producing high‐quality research, teaching, and learning outcomes. The paper seeks to address these issues.Design/methodology/approachA survey was delivered to managers of libraries serving Indonesian public universities. The survey instrument used in this research was based on that used in the neXus2 survey distributed to Australian library managers in 2007. The paper includes a comparison of survey results on key outcomes for Indonesian and Australian library managers.FindingsThe paper reports on the library policies and practices regarding the current level and type of continuing professional development and work place training; and the management, funding and prioritisation of continuing professional development in Indonesian academic libraries.Practical implicationsThe results have implications for the planning and implementation of continuing professional development in Indonesian academic libraries.Originality/valueThis paper reports the results of one of the few major studies of library staff development undertaken in a developing country.
Top executives' international expertise commitment: exploring potential antecedents
Authors: Billing Tejinder K. , Mukherjee Debmalya , Kedia Ben L. , Lahiri Somnath 
Published: November 2010

PurposeThe purpose of this paper is to explore the immediate antecedents of top executives' international expertise commitment. More specifically, the study focuses on the impact of top management characteristics and the international business performance of firms on top management's commitment to developing international expertise in their workforce.Design/methodology/approachPrimary data were collected targeting the top executives of Fortune 500 and INC 500 firms. The final dataset contained responses from 111 top executives.FindingsThe results of the study show that top executives' international experience, perceived importance of international business in career progression, and past, present, and future business performance are positively related to international expertise commitment.Practical implicationsThe findings provide implications for top management hiring decisions. Organizations embarking on the creation of a workforce with international expertise should consider hiring top executives who possess considerable international experience and who perceive international business as an important component in their career progression.Originality/valueOrganizational researchers have devoted very little research attention to exploring what drives top managers to remain committed to developing/acquiring international expertise. This study attempts to fill the void in the extant literature by exploring the immediate predictors and their relative influence on top executives' international expertise commitment.
A suggested typology of Greek upscale hotels based on their MrkIS
Authors: Chatzipanagiotou Kalliopi C. , Coritos Christos D. 
Published: November 2010

PurposeThis paper aims to suggest an empirically based typology of hotels according to their marketing information systems (MrkIS) configurations. The study seeks to examine major antecedents of the effectiveness of MrkIS and their influence on the adoption of specific marketing applications. Finally, this paper seeks to expand the general understanding of the relationship between the effectiveness of a hotel's MrkIS and that hotel's overall effectiveness, compared with that of others from the suggested typology.Design/methodology/approachThe paper collected empirical data from a sample of 254 luxury and five‐star Greek hotels. They conducted a cluster analysis in order to define various clusters of hotels based on their use of specific marketing applications. They considered the role of basic antecedents – namely the hotel's degree of market orientation adoption, system quality, the quality of the information that the MrkIS produce, and support service quality – examining their influence on the MrkIS configuration in use. In addition, the paper considers the relationship between MrkIS effectiveness and overall hotel effectiveness as evidenced throughout the different clusters.FindingsThe study offers insights that can help hoteliers to analyse realistically the potential benefits of MrkIS for their businesses. Toward this end, the paper identifies three specific types of hotels: the “transactional‐oriented”, the “sales‐oriented”, and the “market‐oriented”.Research limitations/implicationsThe results of the study may not be broadly applicable due to differences in national context, hotel category, and other characteristics – a fact that suggests future research opportunities.Practical implicationsBased on the current results, a hotel might better evaluate its existing MrkIS and be prepared to maximise the opportunities offered by the full utilisation of these systems.Originality/valueThe scarcity of empirical evidence with regard to MrkIS utilisation in the lodging industry makes this kind of study essential. The results of the paper expand the general knowledge about hotels' MrkIS adoption, its antecedents, its effectiveness and hotels' overall effectiveness. The results provide an integrated picture of the utilisation of these systems.
Modified silica sols: titania dispersants and co‐binders for silicate paints
Authors: Greenwood Peter 
Published: November 2010

PurposeThe purpose of this paper is to investigate epoxysilane‐modified silica sols as surfactant‐free inorganic pigments dispersants and as co‐binders/reinforcing agents for silicate paints.Design/methodology/approachThe performance of epoxysilane‐modified silica sols as dispersants for titania was studied using a polyacrylate‐based dispersant as reference. Furthermore, the effect of the addition of silica sols, with or without silane modification, to potassium silicate on binder properties was investigated.FindingsSignificant improvements were obtained in stability towards settling in water‐based titania pigments pastes and in light‐scattering efficiency (as much as 50 per cent) for the optimal size of the silica particle of 5 nm. The number of silane molecules per nm2 silica particle surface must exceed a critical value of at least 1 molecule of epoxysilane per nm2 particle surface. Additionally, improved stability towards gelling, water resistance and film‐forming properties of sol‐silicate binder mixes were achieved for epoxysilane‐modified silica sols.Research limitations/implicationsOnly epoxysilane‐modified silica sols were studied in this report. Titania pigment was examined but other important pigments (e.g. iron oxides) remain to be studied. In addition, only sol‐silicate mixes were investigated and not fully formulated silicate paints.Practical implicationsA method that produces stable, high‐performing, surfactant‐free inorganic pigments pastes. Furthermore, stable, high‐ratio, sol‐silicate binders can be obtained with improved water resistance and film properties for use in silicate paints.Originality/valueThe present method provides an easy route to obtain stable surfactant‐free inorganic pigments pastes, as well as makes stable, high‐ratio, sol‐silicate mixes/paints.
IFLA satellite pre‐conference: open access to science information: trends, models and strategies for libraries
Authors: Bowering Mullen Laura 
Published: November 2010

PurposeThe purpose of this paper is to disseminate information about the IFLA pre‐conference in Chania, Crete, Greece on the subject of open access in libraries.Design/methodology/approachReport on visit.FindingsThe main focus of the meeting was open access. Much information was shared.Originality/valueThis is an original work with some quoted material.
Hunting in the shadows for savings: reevaluating standing orders
Authors: Cross Roger L. 
Published: November 2010

PurposeStanding orders are remnants of an early period of library acquisition, and while they can provide a useful service in limited cases most have outlived that usefulness and should be cancelled. In a period of restricted funding and increased digital reliance the need for standing orders has diminished; indeed often the standing orders received are no longer relevant to an institution's mission. However, identifying standing orders is complicated by the nature of their classification as a serial rather than a book or monograph. This paper aims to describe the various types of standing orders and how to identify them.Design/methodology/approachThe paper distinguishes between the yearbook or annual standing order and the non‐sequential and often irregularly published books charged to the serial fund code. The latter type, in the author's experience, makes up the majority of standing orders, and this work argues that on the basis of collection development principles and budgetary realities the majority of standing orders should be cancelled.FindingsThe paper finds that it is necessary to create a stand‐alone database to ensure all standing orders are represented. The review of standing orders cuts materials expenditures, clarifies actual holdings, and eliminates unexpected delivery of materials.Practical implicationsCollection development principles require accountability for resource delivery. Standing orders falsely offer ease at the expense of this responsibility.Originality/valueVery little is written on evaluating standing orders as a separate entity among library holdings. This paper addresses the dual nature of standing orders that allows them to maintain their shadowy existence on serials' accounts as neither book nor journal.