bluuebunny/crossref_metadata_2025_split huggingface dataset:
DeviceEditor visual biological CAD canvas
Authors: Chen Joanna , Densmore Douglas , Ham Timothy S , Keasling Jay D , Hillson Nathan J 
Published: April 2012

Abstract

Background
Biological Computer Aided Design (bioCAD) assists the de novo design and selection of existing genetic components to achieve a desired biological activity, as part of an integrated design-build-test cycle. To meet the emerging needs of Synthetic Biology, bioCAD tools must address the increasing prevalence of combinatorial library design, design rule specification, and scar-less multi-part DNA assembly.

Results
We report the development and deployment of web-based bioCAD software, DeviceEditor, which provides a graphical design environment that mimics the intuitive visual whiteboard design process practiced in biological laboratories. The key innovations of DeviceEditor include visual combinatorial library design, direct integration with scar-less multi-part DNA assembly design automation, and a graphical user interface for the creation and modification of design specification rules. We demonstrate how biological designs are rendered on the DeviceEditor canvas, and we present effective visualizations of genetic component ordering and combinatorial variations within complex designs.

Conclusions
DeviceEditor liberates researchers from DNA base-pair manipulation, and enables users to create successful prototypes using standardized, functional, and visual abstractions. Open and documented software interfaces support further integration of DeviceEditor with other bioCAD tools and software platforms. DeviceEditor saves researcher time and institutional resources through correct-by-construction design, the automation of tedious tasks, design reuse, and the minimization of DNA assembly costs.
Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy
Authors: Nepple Kenneth G , Sandhu Gurdarshan S , Rogers Craig G , Allaf Mohamad E , Kaouk Jihad H , Figenshau Robert S , Stifelman Michael D , Bhayani Sam B 
Published: April 2012

AbstractBackgroundThe adoption of robotic assistance has contributed to the increased utilization of partial nephrectomy for the management of renal tumors. However, partial nephrectomy can be technically challenging because of intraoperative hemorrhage, which limits the ability to identify the tumor margin and may necessitate the conversion to open surgery or radical nephrectomy. To our knowledge, a comprehensive safety checklist does not exist to guide surgeons on the management of hemorrhage during robotic partial nephrectomy. We developed such an safety checklist based on the cumulative experiences of high volume robotic surgeons.MethodsA treatment safety checklist for the management of hemorrhage during robotic partial nephrectomy was collaboratively developed based on prior experiences with intraoperative hemorrhage during robotic partial nephrectomy.ResultsReducing the risk of hemorrhage during robotic partial nephrectomy begins with reviewing the preoperative imaging for renal vasculature and tumor anatomy, with a focus on accessory vessels and renal tumor proximity to the renal hilum. During hilar exposure, an attempt is made to identify additional accessory renal arteries. The decision is then made on whether to clamp the hilum (artery +/- vein). If bleeding is encountered during resection, management is based on whether the bleeding is suspected to be arterial or from venous backbleeding. Operative maneuvers that may increase the chance of success are highlighted in safety checklists for arterial and venous bleeding.ConclusionsSafely performing robotic partial nephrectomy is dependent on attention to prevention of hemorrhage and rapid response to the challenge of intraoperative bleeding. Preparation is essential for maximizing the chance of success during robotic partial nephrectomy.
Phenomenology of depression in older compared with younger adults: Meta-analysis
Authors: Hegeman J. M. , Kok R. M. , van der Mast R. C. , Giltay E. J. 
Published: April 2012

BackgroundLate-life depression may differ from early-life depression in its phenomenology.AimsTo investigate the effect of age on the phenomenology of major depression.MethodA systematic search was conducted in PubMed, Embase and PsycINFO for all studies examining the relation between age and phenomenology of major depression according to RDC, DSM and ICD criteria. Studies were included only if the age groups were compared at the single-item level using the 17-, 21- or 24-item versions of the Hamilton Rating Scale for Depression; a meta-analysis was done for each item of the 17-item scale.ResultsEleven papers met the inclusion criteria. Older depressed adults, compared with younger depressed adults, demonstrated more agitation, hypochondriasis and general as well as gastrointestinal somatic symptoms, but less guilt and loss of sexual interest.ConclusionsThe phenomenology of late-life depression differs only in part from that of early-life depression. Major depression in older people may have a more somatic presentation, whereas feelings of guilt and loss of sexual function may be more prevalent in younger people.
Mental health problems in children and young people from minority ethnic groups: The need for targeted research
Authors: Dogra Nisha , Singh Swaran P. , Svirydzenka Nadzeya , Vostanis Panos 
Published: April 2012

SummaryIn this editorial we argue for the need for better research evidence on the prevalence of child mental health problems in minority ethnic groups, service utilisation among these groups and whether some service barriers are specific for certain groups. Without such evidence it is not possible to influence policy and practice so that evidence-based and appropriate services can be designed and offered to these populations. The terms ethnicity, race and migration are often imprecisely defined, and mental health needs and outcomes vary between immigrants from different generations. There is also a complex interplay between minority status and social class, with terms such as ethnicity being a proxy for multifaceted sociocultural and economic variables. However, we need to start collecting better data on children from minority ethnic groups so that these relationships can be understood, services tailored on the available evidence and ultimately better care delivered to this group of children.
Third-generation neuroimaging in early schizophrenia: Translating research evidence into clinical utility
Authors: Borgwardt Stefan , Fusar-Poli Paolo 
Published: April 2012

SummaryPsychiatric imaging needs to move away from simple investigations of the neurobiology underlying the early phases of schizophrenia to translate imaging findings in the clinical field, targeting clinical outcomes including transition, remission and response to preventive interventions.
Evaluation of teaching an integrated case formulation approach on the quality of case formulations: randomised controlled trial
Authors: Abbas Mohammed , Walton Ruth , Johnston Allan , Chikoore Millicent 
Published: April 2012

Aims and methodThis paper introduces a new approach to producing case formulations, the integrated case formulation (ICF) approach, and a rating scale, the Case Formulation Scale (CFS). Twenty-four psychiatrists participated in a single-blind randomised controlled trial to evaluate the effectiveness of teaching using this new approach. The intervention group (n = 12) received teaching about using ICF, whereas the control group (n = 12) received teaching as usual. The scores on the CFS were compared before and after teaching.ResultsPrior to teaching, psychiatric trainees had poor scores on the CFS. The CFS score for the group taught the ICF approach improved five times more than the control group.Clinical implicationsThis study demonstrates that case formulation skills can be taught. With further improvements, the ICF approach might be useful in the teaching of case formulation.
Colloid and Interface Chemistry under Magnetic Fields
Authors: Sakaguchi Ayumi , Hamasaki Atom , Ozeki Sumio 
Published: April 2012

Abstract
Magneto-Science, a new science of materials using magnetic fields, is recently being developed all over the world. Magneto-Science concerns mainly feeble magnetic materials such as soft matter, carbons, ceramics, and organometals. Colloidal and interfacial systems under magnetic fields are very attractive and important because the dimensions are very much sensitive to magnetic fields. In this review we introduce several examples in colloid and interface chemistry under magnetic fields. Molecular assemblies such as micelles, bimolecular membranes, and vesicles are changed in shape and, in some cases, size and composition by magnetic fields. Since mesophases are sensitive to relatively low magnetic fields, magnetic fields control not only structures and functions but also cooperatively other magnetically insensitive materials. Moreover, a few interesting magnetic responses in hydrogels are summarized.
Monitoring Pioneer Waste Injection Projects in Caspian Sea: Challenges, Lessons Learned, Findings and Recent Advancements
Authors: Gumarov S. M. , Shokanov T. A. , Geehan T.. , McEwen Greg , Rojas J. C. 
Published: April 2012

Abstract
Drilling waste sub-surface disposal, via injecting into a pre-defined suitable formation, known as Waste Injection (WI) technology; has been selected as a primary drilling waste management tool for the development of a major oil field in the Caspian Sea. The field development has been utilizing WI technology since the beginning of development drilling operations. The main drivers were proven track record of the technology, meeting "zero-discharge" environmental requirements and elimination of logistical complications associated with onshore transfer of drill cuttings. A dedicated WI well was drilled and the surface equipment package to process and inject drilling waste was installed on each drilling and production platform.
WI failure was considered as one of the top ten risks to achieving full field production targets. Complexity of the injection horizon consisting mostly of massive mudstone, regional faulting and tectonic activity combined with a lack of local WI experience called for a detailed sub-surface engineering design and meticulous monitoring of the waste disposal domain.
Continuous pressure monitoring was recognized as a critical approach in providing sub-surface assurance and timely identification of any early-warning signatures. Unique to these WI wells, the injection wells were equipped with down-hole pressure-temperature gauges for accurate pressure measurement and subsequent analysis.
This paper discusses the execution, results and conclusions of monitoring this challenging project over a 5-year period, including subsurface complexities experienced during this period such as very high injection pressures, limited fracture-wellbore communication, enhanced solids settling, observation and explanation of long-term pressure trend behaviours. In addition solutions developed to prolong the life of the injection asset; including enhanced seawater "over-flush" injection strategy coupled with down-hole pressure measurement, careful monitoring and analysis.
How to Safely Locate Residential Developments Near Process Plants
Authors: Goyal Ram K , Menon V.. 
Published: April 2012

AbstractFor decades now the oil companies and the communities they operate in the vicinity of have had a kind of love-hate relationship with many ups and downs on the way. On the one hand the communities love the economic benefit and regional advancement that the oil companies bring in their wake while on the other they decry the real as well as imaginary environmental, health or safety related threats posed by the oil, gas and petrochemical plants operating in their midst.As the population increases with time so does the demand for land required for urban development. This by necessity results in building of residential and commercial areas in close proximity of process plants, refinery and other oil handling facilities. This paper highlights the need for mutual cooperation that must exist amongst all parties concerned: the Company, the urbanization and planning bodies, community leaders, public servants, journalists and industrialists. This cooperation can only materialize through mutual trust which in turn can only be generated through a better understanding by all of the actual risks associated with various oil refining and oil handling facilities and the risk mitigation measure that the Company employs to ensure all real risks are reduced to a level as low as is reasonably practicable.The concept of "zero-risk" being attainable in a process environment is infeasible. For land use decision-making we must apply formal techniques of quantitative risk assessment (QRA) and other recognized risk evaluation methods that are being used by many government organizations in Europe and North America. The UK Health and Safety Executive (HSE) have issued quite comprehensive guidelines on this topic which have found acceptance worldwide. This paper briefly explains how the QRA technique works and provides several real life examples of use of QRA in land use planning in Bahrain.There is an immediate need for rational risk mitigation by the Company and rational risk acceptance by the community -- all for the sake of common national interest and vision for the future. Creation of a joint review board working in an advisory capacity might be the answer.
Safety KPIs during Shutdown Turnaround - What to Measure and How to Impact the Overall Economics
Authors: Dowd Darrell , Daher Elie 
Published: April 2012

Abstract
A turnaround is a planned, periodic total or partial shutdown of a refinery process unit or facility to perform maintenance, overhaul and repair operations and to inspect, test and replace process materials and equipment. This is a time sensitive operation that requires a major expenditure and focused project management 24 hour duration. Any delays due to operational or safety issues can adversely impact the shutdown time therefore increasing costs and impacting the revenue of the facility. With a high price of services, the pressure is greater than ever to deliver an efficient turnaround with virtually no incidents and on time. Safety management plays a crucial role in the turnaround activity.
Safety ensures regulations are followed, training and certifications are completed and preventive plans are in place and enforced. It starts by safety contractor selection, followed by a proactive safety plan and a flawless and timely execution.
How do we ensure that the safety management is conducted efficiently in order to impact the bottom line of the turnaround and limit delays?
Research by Liberty Mutual Research Institue for Safety demonstrates that for every $1 invested in safety there is a $3 to $6 return on investment, and our own research tells us that for every $1 spent on "tool time", $7 is spent on service costs associate with that work. Organizations need to aim for a safety excellence culture as this contributes to profitability and benefits employees and c ommunities. Safety excellence is the result of an effective safety management process. In order to monitor safety excellence, we will illustrate a system we call "The Safety Process Map".
This paper explores the deliverables generated by this map and the value they bring to turnarounds and shutdowns. These deliverables move beyond the standard Total Recordable Incident Frequency (TRIF) or Lost Time incidents reporting by auditing conformance to policies and procedure around activities like work permits issued and Confined Space Entry (CSE). Our position is that a process that can systemically identify when and why non-conformance to policy and procedure occur offers the opportunity for proactive mitigation activities. These proactive activities act on what we believe are often the root causes of negative incidents.
Recent Developments in Gas Flaring and Venting Reduction
Authors: Aliabadi A.. , Shamekhi A.. 
Published: April 2012

Abstract
With the extraction of crude oil from several kilometers below the earth surface usually some associated gas comes to the surface as well. If there are not enough gas infrastructures or a nearby gas market in the area of the oil production, a significant portion of the associated gas may be vented or flared in the atmosphere. The importance of reduction of flaring or venting of natural gas can be mentioned from two aspects. Firstly, natural gas is a valuable source of energy. The national oceanic and atmospheric administration estimates 134 bcm of associated gas were flared worldwide in 2010. This is roughly equivalent to 5% of the world's total gas consumption, or 30% of the European Union gas consumption. Secondly, burning any kind of fossil fuel emits carbon dioxide as the main green house gas into the atmosphere which leads to global warming. This work presents recent developments in gas flaring and venting reduction throughout the world. The best way of gas flaring reduction is using associated gas as a source of energy or re-injecting it into the reservoir in order to increase oil production. Associated gas can be used to generate electricity or be transported by pipeline to consumption points. In some areas liquefied natural gas (LNG) or gas-to liquids (GTL) projects may make economic sense. Economically using of the associated gas depends on the volume of production and the distance to markets.
Sharing of HSE Lessons Through E-Messaging Tool
Authors: Tamarra Robinson , Macwan Nancy 
Published: April 2012

Abstract
Effective communications are essential for continuing improvement of HSE Culture and to that end ensuring HSE is efficiently communicated to the workforce.
Therefore, a new e-messaging tool has been developed by HSE&QA Division and IT Division, and has been implemented in a way that is available to all employees onshore & offshore. The tool requires no additional software and uses the power of Outlook to create and send messages. Outlook supports a wide variety of email accounts providing flexibility in sending messages to any account.
The HSE message is placed in the footer of every email that is sent and received within the company network everyday. This in turn enables ADMA as it: Clearly demonstrates commitment of HSE&QA Division towards HSE PerformanceCommunicates HSE efficiently to the entire workforce through emails sent everyday within the company and externally to contractors, service providers, other ADNOC Group of CompaniesHigh-return awareness tool, powerful and low costAlerts the recipient to special news and enables them to have access to linksMotivates employees with a strong, distinct HSE oriented message, offering tips on promoting the company's HSE corporate vision in all HSE matters.Personalizing messages with HSE Tips & Information, promoting health & wellness of staffSignificantly reduces the chances of incident / trends
Contractor Safety Management
Authors: Al-Saeedi Mohammed Jasem , Al-Anezi Nayef Abdullah , Palagummi Subba Rao , Gopalan Sridhar , Latheef Abdul , Thakkar Jigneshkumar 
Published: April 2012

Abstract
"We Believe Contractors are our Partners in Business"
Business partners carryout majority of our activities. Drilling is the most hazardous real estate on the earth. We do not differentiate Kuwait Oil Company (KOC) and Business partners while reporting HSE Statistics as we share their sorrow and happiness equally (Every incident occurs in any area of operation with our Business Partners is counted as KOC incident).
We own and take the responsibility to investigate all the incidents and lessons learned are shared on weekly basis with all our Rigs & other groups of KOC to prevent recurrence of such incidents in future.
COMMON HSE OBJECTIVES
Effective coordination to create a better partnership Duty of Care demonstration by the leadership Improve the image of the company (Both KOC & Business partners) Compliance to HSE MS procedures of KOC and Business partners through proper bridging.
As appropriate to the risks associated with drilling operations, the evaluation and selection process for the business partners shall consider the adequacy of their HSE Management practices, their HSE performance record and their ability to perform work in a responsible manner consistent with the KOC HSE Management System. Risk register is prepared to identify all the hazards and risks associated with the operations, camp and office areas and communicated to the business partners to consider during risk assessments at rig sites. This risk register is reviewed on yearly basis and/or whenever there is an occurrence of serious incidents in drilling operations. Appropriate recommendations will be captured in the risk register and addressed.
We do identify the interfaces between KOC and our Business partners and effectively managed. KOC shall provide clear deliverables and performance standards like HSE KPIs shall be agreed and monitor compliance to the set KPIs on monthly basis and detailed review on Quarterly basis. Also we have a bridging document with the KOC and Business partners HSE MS to ensure both are in the same page when it comes to HSE Management.
A training matrix is also provided in line with KOC HSE MS and business partners are advised to comply to the matrix and majority of the times they supersedes our requirements which is a good sign as we consider.
Managing Security in Turbulent Times: A Middle East Case Study
Authors: Langford James , López Juan Carlos 
Published: April 2012

Abstract
Security is an on-going concern across the oil and gas industry. During turbulent times such as civil unrest, riots, states of emergency, demonstrations, protests or natural disasters, managing security poses additional risks that may lead to employee evacuations and disruption of business activities. This paper describes how an oilfield services company applied management commitment and leadership concepts to day-to-day operational and personnel security decisions during turbulent times across the Middle East region.
The paper describes how the company established a holistic approach to manage the additional risks associated with threat environments, taking into consideration the particularities of specific country, city and field operations. Clear priority has been given to protect employees, contractors and dependants, both nationals and expatriates.
DOIRC: An Effective Communication Tool in Improving Drilling Safety Culture
Authors: Boucif Mustapha Nasr-Eddine , Al Hammadi Adel 
Published: April 2012

Abstract
Abu Dhabi Company for Onshore Oil Operations (ADCO) Drilling Division and its Contractors have managed to reach and maintain world class performance in HSE for the past three years and recorded the lowest Total Recordable Injury Rate (TRIR), the second lowest Lost Time Injury Frequency (LTIF) in ADCO's Drilling Division history and the longest time without LTI (Eighteen months without LTI). In addition we have recorded zero car related injuries and zero spills in 2011. ADCO believes that the most fundamental factor affecting HSE performance is what is commonly referred to as "safety culture". The strongest influence upon culture within most organizations is "the message from the top management".
DOIRC (Drilling Operations Incident Review Committee) program improved subsequently both vertical (ADCO management and rig site) and horizontal (ADCO and its contractors) communication and was a key factor in setting in place an effective 360° communication. The success of the program shows clearly that the behavior of all stakeholders in Drilling can be changed by an effective communication, visible commitment and involvement from the top management. By keeping a permanent physical and contact between drilling crews, service providers and top management of ADCO and its Contractors, the impact on the safety behavior of the drilling crews was changed since then.
The DOIRC program was the key factor for ADCO Drilling to reach and maintain a world class performance for the past three years, reaching 0.52 TRIR in 2011, the lowest in ADCO drilling history and more than twenty million kilometers driven without injuries.