bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends in Suicidality and Bullying among New York City Adolescents across Race and Sexual Identity: 2009–2019
Authors: English Devin , Kelman Elizabeth , Lundy De La Cruz Nneka , Thompson Azure B. , Le Karolyn , Garretson Marné , Viswanath Aishwarya L. , Brahmbhatt Diksha , Lockwood Cynthia , Busby Danielle R. , Davila Marivel 
Published: May 2024

AbstractDespite evidence showing rising suicidality among lesbian, gay, and bisexual (LGB) and Black adolescents, separately, there is scant research on suicide risk trajectories among youth groups across both racial and sexual identities. Thus, we examined trajectories of self-reported suicidal ideation and attempt and their associations with bullying among New York City-based adolescents. We analyzed 2009–2019 NYC Youth Risk Behavior Survey data. We ran weighted descriptive and logistic regression analyses to test for trends in dichotomous suicidal ideation, suicide attempt, bullying at school, and e-bullying variables among students across both race/ethnicity and sexual identity. We assessed associations between suicidality trends and bullying with logistic regressions. Models controlled for age and sex. Suicidal ideation and attempt were 2 and 5 times more likely among LGB than heterosexual participants, respectively. Bullying at school and e-bullying were 2 times more likely among LGB than heterosexual participants. Black LGB participants were the only LGB group for which both suicidal ideation (AOR = 1.04, SE = .003, p < .001) and attempt (AOR = 1.04, SE = .004, p < .001) increased over time. Both increased at accelerating rates. Conversely, White LGB participants were the only LGB group for which both suicidal ideation (AOR = 0.98, SE = .006, p < .001) and attempt (AOR = 0.92, SE = .008, p < .001) decreased over time. These changes occurred in parallel with significant bullying increases for Black and Latina/o/x LGB adolescents and significant bullying decreases for White LGB adolescents. Bullying was positively associated with suicidal ideation and attempt for all adolescents. Findings suggest resources aimed at curbing rising adolescent suicide should be focused on Black LGB youth.
Advances in CALPHAD Methodology for Modeling Hydrides: A Comprehensive Review
Authors: Palumbo M. , Dematteis E. M. , Fenocchio L. , Cacciamani G. , Baricco M. 
Published: May 2024

AbstractHydrides enable handling hydrogen at low pressure and near room temperature, offering higher volumetric densities than compressed or liquid hydrogen and enhancing safety. The CALPHAD method, rooted in the principles of thermodynamics, offers a systematic approach for predicting phase equilibria and thermodynamic properties in multicomponent materials. This comprehensive review paper aims to provide a detailed overview of the application of the CALPHAD method in the realm of metallic and complex hydrides. After an introduction to the fundamental thermodynamic aspects of hydrides, key elements of applying the CALPHAD method to model metal-hydrogen systems and complex hydrides are discussed. Subsequently, recent publications are reviewed, highlighting key findings and recent progresses in the field. Finally, the challenges that must be overcome to achieve further progress in this area are explored.
Residents underestimate their robotic performance: evaluating resident robotic console participation time
Authors: Yoder Lauren , Elson Nora , Fellner Angela N , Meister Katherine , Guend Hamza 
Published: May 2024

AbstractLack of formal national robotic curriculum results in a void of knowledge regarding appropriate progression of autonomy in robotic general surgery training. One midwestern academic surgical training program has demonstrated that residents expect to independently operate more on the robotic console than they perceive themselves to do. As such, our study sought to evaluate expectations of residents and faculty regarding resident participation versus actual console participation time (CPT) at a community general surgery training program. We surveyed residents and faculty in two phases. Initially, participants were asked to reflect on their perceptions and expectations from the previous six months. The second phase included surveys (collected over six months) after individual cases with subjective estimation of participation versus CPT calculated by the Intuitive Surgical, Inc. MyIntuitive application. Using Mann–Whitney U-Test, we compared resident perceptions of CPT to actual CPT by case complexity and post-graduate year (PGY). Faculty (n = 7) estimated they allowed residents to complete a median of 26–50% of simple and 0–25% of complex cases in the six months prior to the study. They expected senior residents (PGY-4 and PGY-5) to complete more: 51–75% of simple and 26–50% of complex cases. Residents (n = 13), PGY-2–PGY-5, estimated they completed less than faculty perceived (0–25% of simple and 0–25% of complex cases). Sixty-six post-case (after partial colectomy, abdominoperoneal resection, low anterior resection, cholecystectomy, inguinal/ventral hernia repair, and others) surveys were completed. Residents estimated after any case that they had completed 26–50% of the case. However, once examining their MyIntuitive report, they actually completed 51–75% of the case (median). Residents, especially PGY-4 and 5, completed a higher percentage than estimated of robotic cases. Our study confirms that residents can and should complete more of (and increasingly complex) robotic cases throughout training, like the transition of autonomy in open and laparoscopic surgery.
Indocyanine green (ICG) fluorescence technology in pediatric robotic surgery
Authors: Esposito Ciro , Masieri Lorenzo , Cerulo Mariapina , Castagnetti Marco , Del Conte Fulvia , Di Mento Claudia , Esposito Giorgia , Tedesco Francesco , Carulli Roberto , Continisio Leonardo , Chiodi Annalisa , Escolino Maria 
Published: May 2024

AbstractThis study aimed to report our experience in indocyanine green (ICG) fluorescence-guided surgery (FGS) in pediatric robotics. The data of 55 patients (35 boys and 20 girls), who underwent robotic surgery using ICG fluorescence in three institutions over the last 7 years, were retrospectively reviewed. The following robotic procedures were included: pyeloplasty (n = 21), complex Lich–Gregoir ureteral reimplantation (n = 8), varicocelectomy (n = 7), adnexal pathology resection (n = 8), partial nephrectomy (n = 4), nephrectomy (n = 4), renal cyst removal (n = 2), and excision of prostatic utricle (n = 1). The ICG was injected intravenously in all indications except for varicocele where intratesticular injection was done, and prostatic utricle or paraureteral diverticulum where trans-catheter injection was done. The ICG dosage was 0.2–0.3 mg/mL/kg. All the procedures were performed using da Vinci Xi platform. Firefly® allowed to switch form bright light to ICG-NIRF view and vice versa. All the procedures were accomplished in robotics without conversions to laparoscopy or open surgery. No episodes of allergy or anaphylaxis to ICG were recorded. An excellent ICG-NIRF view of target organs was obtained in all procedures. Based on our experience, we believe that application of ICG FGS in pediatric robotics enhances the identification of critical anatomical elements and pathological structures, thereby positively impacting both oncological and functional outcomes. This technique is safe, feasible, and versatile. We advocate the consideration of ICG as the standard of care in certain procedures such as partial nephrectomy, varicocele repair, tumor resection, and ovarian torsion. Nonetheless, further investigations are warranted to explore its potential broader applications in pediatric urology.
Integer syndrome decoding in the presence of noise
Authors: Drăgoi Vlad-Florin , Colombier Brice , Cayrel Pierre-Louis , Grosso Vincent 
Published: May 2024

AbstractCode-based cryptography received attention after the NIST started the post-quantum cryptography standardization process in 2016. A central NP-hard problem is the binary syndrome decoding problem, on which the security of many code-based cryptosystems lies. The best known methods to solve this problem all stem from the information-set decoding strategy, first introduced by Prange in 1962. A recent line of work considers augmented versions of this strategy, with hints typically provided by side-channel information. In this work, we consider the integer syndrome decoding problem, where the integer syndrome is available but might be noisy. We study how the performance of the decoder is affected by the noise. First we identify the noise model as being close to a centered in zero binomial distribution. Second we model the probability of success of the ISD-score decoder in presence of a binomial noise. Third, we demonstrate that with high probability our algorithm finds the solution as long as the noise parameterdis linear int(the Hamming weight of the solution) andtis sub-linear in the code-length. We provide experimental results on cryptographic parameters for the BIKE andClassic McEliececryptosystems, which are both candidates for the fourth round of the NIST standardization process.
New proboscidean specimens from the Late Miocene of Romania: the huge-sized deinothere Deinotherium proavum, the rare “Mammut” cf. obliquelophus and the first description of the shovel-tusker Konobelodon from the country
Authors: Konidaris George E. , Rățoi Bogdan G. , Badea Daniel D. , Ursachi Laurențiu 
Published: May 2024

AbstractIn this article, we describe so far unpublished proboscidean specimens from several Late Miocene localities of Romania. A partial mandible and the complete upper/lower cheek tooth rows of a deinothere individual from the site of Gherghești 1 belong to Deinotherium proavum and comprise one of the few examples of entire cheek tooth rows of the same individual of this species. Gherghești 1 is geographically close to Mânzaţi from where the celebrated skeleton of “Deinotherium gigantissimum” was discovered at the end of the nineteenth century, and thus further highlights the importance of Romania in the study of this emblematic deinothere. Deinotherium proavum represents the last deinothere species in Europe and corresponds to the terminal stage of the size increase characterizing the evolution of European deinotheres. Two zygodont molars are attributed to the rare “Mammut” cf. obliquelophus and add to the scarce record of “Mammut” in the Miocene of Eurasia. They document the secure presence of “Mammut” in the Miocene of Romania. The small size of the studied molars compared to known specimens of the Pliocene “Mammut” borsoni and the weak development of the distal cingulum in the lower third molars may have taxonomic and biostratigraphic importance. Furthermore, the presence of an amebelodontid is documented by a large-sized and dorsoventrally flattened lower tusk fragment that shows tubular dentine in its inner part and is attributed to the tetralophodont shovel-tusker Konobelodon. This specimen marks the first record of the genus in Romania. Finally, the biostratigraphic distribution of the taxa is discussed.
Exploration of the influence of GOLGA8B on prostate cancer progression and the resistance of castration-resistant prostate cancer to cabazitaxel
Authors: Li Haopeng , Wang Xin’an , Zhai Menghe , Xu Chengdang , Chen Xi 
Published: May 2024

AbstractCastration-resistant prostate cancer (CRPC) represents the final stage of prostate cancer (PCa). Cabazitaxel, a taxane chemotherapy drug, is used in treating CRPC. However, patients with CRPC eventually develop resistance to cabazitaxel, and the underlying mechanism remains unclear. Here, we aimed to investigate potential genetic alterations that may play a role in CRPC resistance to cabazitaxel. Using microarray data from the GSE158494 dataset, we identified ten critical genes (CXCL8, ITGB8, CLIP4, MAP1B, WIPI1, MMP13, CXCL1, C1S, GOLGA8B, and CXCL6) associated with CRPC cell resistance to cabazitaxel. The potential function of these key genes in PCa progression was analyzed using different databases, including Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and Chinese Prostate Cancer Genome and Epigenome Atlas (CPGEA). Our findings revealed altered expression of these genes in the development of PCa. Furthermore, CXCL1 and GOLGA8B were found to influence the disease-free survival (DFS) status of patients with PCa, with GOLGA8B affecting the overall prognosis in patients with PCa. Additionally, GOLGA8B expression was associated with the infiltration of various immune cells in PCa, and it was upregulated in clinical PCa and CRPC samples. Through CCK-8 assays, we established that GOLGA8B could influence the sensitivity of CRPC cells to cabazitaxel and docetaxel. In conclusion, we identified GOLGA8B as a crucial gene that influences PCa progression and contributes to CRPC resistance to cabazitaxel.
Elucidating the impact of parthanatos-related microRNAs on the tumoral immune microenvironment and clinical outcome in low-grade gliomas
Authors: Zhu Penglei , Wu Hao , Zheng Buyi , Wang Hua , Zou Yi 
Published: May 2024

AbstractParthanatos, a cell death mechanism triggered by PARP-1 activation, is implicated in oncogenic processes, yet their role in low-grade gliomas (LGG) remains poorly understood. This research investigates Parthanatos-related miRNAs' prognostic and immunomodulatory potential, alongside their influence on therapeutic outcomes in LGGs. Comprehensive miRNA and mRNA profiles of LGG patients were extracted from TCGA and CGGA databases, integrating clinical parameters to identify Parthanatos-associated miRNAs. IHC data validated the expression levels of Parthanatos-related genes in glioma versus normal brain tissues. Protein–protein interaction networks and Spearman correlation analysis facilitated the identification of key miRNAs. Parthanatos-related miRNA indices (PMI) were screened using Lasso and assessed for their accuracy in predicting prognosis, comparing their associated potential molecular functions and heterogeneity of the immune microenvironment. Drug sensitivity was assessed between different groups and optimal therapeutic agents were predicted. Validate the expression levels of key miRNAs by qPCR. Ninety-one miRNAs significantly associated with Parthanatos were screened, through which a PMI prognosis model of nine miRNAs was constructed. The PMI score was able to independently predict the prognosis of patients with LGG, and the nomogram constructed based on the PMI provided a practical tool for clinical prediction of patient prognosis. The proportion of immune response was lower in patients in the high-risk group, and there were significant differences in drug sensitivity between different risk classes, while drugs such as Fasudil were identified as the most promising therapeutic agents for patients in the high-risk group. Our findings highlight the critical role of Parthanatos-associated miRNAs in the progression and treatment of LGG, offering novel insights into their prognostic value and therapeutic potential.
Acceptability and Feasibility of Survivorship Group Medical Visits for Breast Cancer Survivors in a Safety Net Hospital
Authors: Trejo Evelin , Velazquez Ana I. , Castillo Elizabeth , Couey Paul , Cicerelli Barbara , McBride Robin , Burke Nancy J. , Dixit Niharika 
Published: May 2024

AbstractProviding cost-effective, comprehensive survivorship care remains a significant challenge. Breast cancer survivors (BCS) who have limited income and are from marginalized racial and ethnic groups experience a worse quality of life and report higher distress. Thus, innovative care models are required to address the needs of BCS in low resource settings. Group medical visits (GMV), utilized in chronic disease management, are an excellent model for education and building skills. This single-arm intervention study was conducted at a public hospital in California. GMVs consisted of five 2-h weekly sessions focused on survivorship care planning, side effects of treatment and prevention, emotional health, sexual health, physical activity, and diet. The patient navigators recruited three consecutive GMV groups of six English-speaking BCS (N = 17). A multidisciplinary team delivered GMVs, and a patient navigator facilitated all the sessions. We used attendance rates, pre- and post-surveys, and debriefing interviews to assess the feasibility and acceptability of the intervention. We enrolled 18 BCS. One participant dropped out before the intervention started, 17 BCS consistently attended and actively participated in the GMV, and 76% (13) attended all planned sessions. Participants rated GMVs in the post-survey and shared their support for GMVs in debriefing interviews. The BCS who completed the post-survey reported that GMVs increased their awareness, confidence, and knowledge of survivorship care. GMVs were explicitly designed to address unmet needs for services necessary for survivorship care but not readily available in safety net settings. Our pilot data suggest that patient-navigator-facilitated GMVs are a feasible and acceptable model for integrating survivorship care in public hospitals.
Eliciting risk preferences in an artefactual field experiment via replication and an alternative approach
Authors: Jozwik Jan 
Published: May 2024

AbstractThis paper investigates risk preferences using an artefactual field experiment conducted with a non-standard subject pool of farmers in Ghana. I introduce an alternative methodology for studying preferences following replication of a seminal risk elicitation procedure by Binswanger (Am J Agric Econ 62(3):395407, 1980). An important feature of both approaches is that they are easy to understand and, hence, are particularly suitable for eliciting preferences among subjects with low levels of formal education. I successfully replicate Binswanger's study, documenting how his original result of the moderate level of risk aversion for an average farmer can be generalized to a different country. However, using my alternative approach, whereby lotteries are presented in the loss domain, I find that half of my experimental subjects violated expected utility theory. This approach is of relevance to the current literature on studying risk preferences among subjects with poor literacy skills.
Computational Organic Chemistry: The Frontier for Understanding and Designing Bioorthogonal Cycloadditions
Authors: Svatunek Dennis 
Published: May 2024

AbstractComputational organic chemistry has become a valuable tool in the field of bioorthogonal chemistry, offering insights and aiding in the progression of this branch of chemistry. In this review, I present an overview of computational work in this field, including an exploration of both the primary computational analysis methods used and their application in the main areas of bioorthogonal chemistry: (3 + 2) and [4 + 2] cycloadditions. In the context of (3 + 2) cycloadditions, detailed studies of electronic effects have informed the evolution of cycloalkyne/1,3-dipole cycloadditions. Through computational techniques, researchers have found ways to adjust the electronic structure via hyperconjugation to enhance reactions without compromising stability. For [4 + 2] cycloadditions, methods such as distortion/interaction analysis and energy decomposition analysis have been beneficial, leading to the development of bioorthogonal reactants with improved reactivity and the creation of orthogonal reaction pairs. To conclude, I touch upon the emerging fields of cheminformatics and machine learning, which promise to play a role in future reaction discovery and optimization.
Which Cyclaneusma minus morphotypes are responsible for needle cast of Pinus spp. in Slovakia?
Authors: Ondruskova Emilia , Kobza Marek , Janosikova Zuzana , McDougal Rebecca , Adamcikova Katarina 
Published: May 2024

AbstractCyclaneusma needle cast (CNC) is a needle disease which caused deterioration of vitality and reduction in the growth of pines. The disease is caused by the ascomycetous fungus Cyclaneusma minus, which has two well-described morphotypes; C. minus simile and C. minus verum. The distribution and host range of C. minus simile and verum was determined from needle samples and isolates collected throughout Slovakia from 2014 to 2020. Samples from 111 localities, 11 pine host species and 245 trees collected in different types of planting were analysed. It was found, that both morphotypes are present, but C. minus verum is predominantly responsible for CNC in urban and forest plantings in Slovakia. C. minus verum was positively detected in more than 88% of collected samples, whereas C. minus simile was only in four samples from three localities. Morphotype-specific primers were sufficiently sensitive even for new pine-host species. The host range of C. minus simile and C. minus verum was enriched worldwide. C. minus verum was observed in nine host species, whereas C. minus simile was identified only in one. Cyclaneusma niveum was also recorded and its presence was confirmed through DNA sequencing.
Bullying Victimization as an Adverse Experience for Psychosocial Adjustment among Irish Adolescents
Authors: D’Urso Giulio , Caravita Simona Carla , Symonds Jennifer 
Published: May 2024

AbstractThis study investigates the long-term effects of victimization from middle adolescence to late adolescence and early adulthood, examining emotional and behavioral problems, peer relationships, and smoking habits and sleeping difficulties. The study also explores how these outcomes can persist into early adulthood, taking into consideration early victimization experiences, gender, cognitive ability, and family social class. The total sample included 7525 participants, spanning the ages of 13, 17, and 20, from the Child Cohort of the Growing Up in Ireland study (48.9% male). The path analysis model suggests that victimization is associated with behavioral problems at age 17, and it is also linked to emotional problems and sleeping difficulties at both ages 17 and 20. Additionally, sleeping difficulties, smoking habits, and indices of emotional and behavioral adjustment exhibit some stability between ages 13 and 17, as well as 17 and 20. Theoretical and practical implications are discussed.