bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional Sensitivity in Human-Computer Interaction
Authors: Kim Jonghwa , Wagner Johannes , Vogt Thurid , André Elisabeth , Jung Frank , Rehm Matthias 
Published: November 2009

Abstract
Human conversational partners usually try to interpret the speaker´s or listener´s affective cues and respond to them accordingly. Recently, the modelling and simulation of such behaviours has been recognized as an essential factor for more natural man-machine communication. The implicit emotion channels of human communication such as speech, facial expression, gesture, and physiological responses are used in general to extract emotion-relevant features for the computational perception of emotion. So far, research on emotion recognition has mostly dealt with offline analysis of recorded emotion corpora, and online processing (in realtime or near realtime) has hardly been addressed. Online processing is, however, a necessary prerequisite for the realization of human-computer interfaces that analyze and respond to the user´s emotions while he or she is interacting with an application. In this paper, we first describe how we recognize emotions from various modalities including speech, gestures and biosignals. We then present Smart Sensor Integration (SSI), a framework which we developed to meet the specific requirements of online emotion recognition.
Tangible, Embedded, and Reality-Based Interaction
Authors: Döring Tanja , Krüger Antonio , Schmidt Albrecht , Schöning Johannes 
Published: November 2009

AbstractTangible, embedded, and reality-based interaction are among novel concepts of interaction design that will change our usage of computers and be part of our daily life in coming years. In this article, we present an overview of the research area of tangible, embedded, and reality-based interaction as an area of media informatics. Potentials and challenges are demonstrated with four selected case studies from our research work.
Mobile Digital Media: Challenges and Opportunities
Authors: Aras Hidir , Feige Sebastian , Malaka Rainer , Walther-Franks Benjamin , Wenig Dirk 
Published: November 2009

Abstract
The use of digital media in mobile surroundings has a massive influence on the type of content consumed and produced, its presentation form and how interactive access is guaranteed in such mobile contexts. To fully leverage the possibilities that digital media offer in mobile use, it is necessary to understand this influence and approach it with appropriate concepts. This article gives an overview of the impact of novel devices, diverse contexts of use, and changed demands on digital content and the interaction with it. Works of the authors and others are presented as examples for how possibilities are created and used to produce digital media optimised for mobile use.
Modellbasierte Bildmodifikation
Authors: Blanz Volker 
Published: November 2009

Zusammenfassung
Die Verwendung realer Bild- und 3D Scandaten in digitalen Medien ermöglicht es, photorealistische Inhalte effizient zu generieren. Um die Daten einbinden und modifizieren zu können, ist jedoch aufwändige Technologie erforderlich. Der Artikel beschreibt einen statistischen, lernbasierten Ansatz, der menschliche Gesichter rekonstruieren, modifizieren, animieren und in Bildern austauschen kann.
Medieninformatik NXG — Die nächste Generation: Wie Kinder und Jugendliche heute die Medien von morgen erlernen können
Authors: Herczeg Michael 
Published: November 2009

Zusammenfassung
Die Medieninformatik ist eines der jüngsten Teilgebiete der Informatik. Seit etwa 1990 werden Begriffsdefinitionen, Hochschul-Curricula und Forschungsagendas entwickelt und umgesetzt, um dieses interdisziplinäre Gebiet zu klären und nachhaltig zu entwickeln. In diesem Beitrag soll die Frage gestellt werden, welche Rolle die Medieninformatik für die Generation spielen kann, die gerade in der Schule auf Studium und Beruf vorbereitet wird. Dazu soll dargestellt und diskutiert werden, wie schon heute Kinder und Jugendliche auf diese moderne, interdisziplinäre Form der Informatik eingestimmt, vorbereitet und motiviert werden können. Anstatt sich auf Algorithmen und Datenstrukturen sowie auf mathematische Grundlagen zu beschränken, sollte diese Generation bereits heute mit den interaktiven Medien von morgen umzugehen lernen. Seit 2001 wird an deutschen Schulen und Vorschulen im Rahmen der Forschungs- und Transferinitiative KiMM (Kids in Media and Motion) ein dieser Zielsetzung entsprechender projektorientierter Unterricht durchgeführt, der Kindern und Jugendlichen vor allem neue körper- und raumbezogene digitale Medien nahe bringt, indem sie interaktive mediale Systeme selbst entwickeln und anwenden. Der Unterricht findet unter Berücksichtigung der vorhandenen schulischen Curricula in praktisch allen Schulfächern meist fachübergreifend statt und macht die Medieninformatik und damit auch die Informatik in der Schule zu einer neuen Querschnittsdisziplin.
DFG Research Training Group 722 Use of Information Technologies for Precision Crop Protection
Authors: Oerke Erich-Christian , Gerhards Roland 
Published: November 2009

Abstract
In an interdisciplinary approach Research Training Group 722 investigates methods and technologies for a site-specific and efficient control of weeds, pathogens, and nematodes in agricultural crops. By utilizing and developing innovative sensor techniques, geo-information systems, data processing and control techniques, pest control measures are applied only if, when and where economically needed. The spatial and temporal heterogeneity of incidence and distribution of pests in the field is assessed using remote sensing techniques and global positioning systems. For on-line and off-line applications these data are analysed in decision support systems considering a spatial component. Spatially and temporally precise pest control is achieved by using sensor-guided equipment. The short-term effects, i. e., the efficacy of control of weeds and diseases, and long-term effects of site-specific control strategies on the incidence and distribution of pests in the field are monitored by using technical sensors again. The documentation of all steps in these pest management systems may contribute to develop new production standards and to demonstrate the ecologic benefits of this crop protection strategy. The generation and management of information on the incidence of pests with high spatial resolution and its implementation in precise control systems will enable a targeted and resource-preserving integrated pest management system under high productivity conditions, which is economically successful, environmentally sound and socially acceptable.
Elektronische Verhandlungssysteme und ihre Rolle in der betrieblichen Kommunikation — Eine explorative Untersuchung der Beschaffungsauktion
Authors: Köhne Frank 
Published: November 2009

Zusammenfassung
Die Arbeit untersucht die Rolle von elektronischen Beschaffungsauktionen anhand von branchenübergreifenden, narrativen Interviews. Defizite in Bezug auf interorganisationale Kommunikation werden mit Mitteln der Language Action Perspective (LAP) sowie der Spieltheorie aufgedeckt und analysiert.
Lower early morning plasma cortisol levels are associated with thyroid autoimmunity in the elderly
Authors: Terzidis K , Panoutsopoulos A , Mantzou A , Tourli P , Papageorgiou G , Saltiki K , Mara C , Alevizaki M 
Published: November 2009

ObjectivesThyroid autoimmunity decreases in the very old. We investigated whether glucocorticoid (GC) activity, which increases in old age, is involved in this process.Subjects and methodsA total of 321 ambulatory subjects (age 51–95 years, median 71, 207 female) were studied. Thyroid function tests, cortisol, glucose, insulin and biochemical parameters were measured. A modified overnight dexamethasone suppression test (0.25 mg) was performed as an index of GC sensitivity.ResultsForty subjects had positive anti-thyroid peroxidase antibodies and 36 had positive anti-thyroglobulin antibodies, while 57 had either one or the other or both thyroid autoantibodies (ThAbs) positive. Mean basal cortisol levels were significantly lower in the ThAbs (+) groups (320±125 vs 378±128 nmol/l, P=0.002). Triiodothyronine, free thyroxine, post-dexamethasone cortisol levels, C-reactive protein, homeostasis model assessment-insulin-resistance-index and body mass index did not differ between these two groups. Mean age of ThAbs (+) subjects was lower compared to the ThAbs (−) group (67.38±7.38 vs 71.64±8.57 years, P=0.001).ConclusionsReduced GC activity is associated with an increased prevalence of ThAbs positivity in older ambulatory subjects. Subjects without ThAbs in this population sample are relatively older. It is not known whether this is related to increasing GC activity with age.
Trough serum testosterone predicts the development of polycythemia in hypogonadal men treated for up to 21 years with subcutaneous testosterone pellets
Authors: Ip Flora F , di Pierro Irene , Brown Ross , Cunningham Ilona , Handelsman David J , Liu Peter Y 
Published: November 2009

ObjectivesTestosterone formulations that have more steady-state pharmacokinetics, such as subcutaneously implanted testosterone pellets, may cause less erythrocytosis than i.m. injections of shorter acting androgen esters. We, therefore, sought to define the prevalence, predictors, and proximate basis (role of erythropoietin) for polycythemia (hematocrit >0.50) in hypogonadal men receiving testosterone implants long term.DesignA cross-sectional study was conducted in an academic andrology center with a longitudinal subgroup analysis.PatientsA total of 158 hypogonadal men aged 14–84 years (mean age 46.7 years) treated on average for 8 years (range 0–21 years).MeasurementsTrough blood testosterone and hematocrit. Serial serum erythropoietin concentrations were measured in 16 volunteers.ResultsPositive univariate associations between polycythemia (hematocrit >0.50) and log(testosterone) (odds ratio (OR) 24.7, 95% confidence interval (CI): 4.3, 141.2, P<0.01) and age (OR 1.1, 95% CI: 1.0, 1.1, P=0.03) and a borderline relationship with current smoking (OR 4.2, 95% CI: 0.9, 20.0, P=0.08) were unveiled. A sensitivity analysis using alternate definitions of polycythemia was performed to capture all potential covariants. Multivariate regression analysis incorporating all potential covariants disclosed the independent OR of developing polycythemia (after adjusting for smoking and age) for log(testosterone) to be 15.0 (95% CI: 2.5, 90.8). Duration of testosterone therapy did not alter the risk of polycythemia. A direct relationship between testosterone and erythropoietin was observed (P=0.05).ConclusionsHigher trough serum testosterone concentrations but not duration of treatment predict the development of polycythemia in men receiving long-acting depot testosterone treatment.
Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma
Authors: Wortmann Sebastian , Quinkler Marcus , Ritter Christian , Kroiss Matthias , Johanssen Sarah , Hahner Stefanie , Allolio Bruno , Fassnacht Martin 
Published: November 2009

ObjectiveNo standard therapy for advanced adrenocortical carcinoma (ACC) is established by any randomized trial but a consensus conference 2003 recommended mitotane as monotherapy or combined with etoposide, doxorubicin and cisplatin or with streptozotocin as first-line systemic therapy. However, there is no evidence for any therapy beneficial in patients failing these therapies. Therefore, we evaluated the effects of the anti-VEGF antibody bevacizumab plus capecitabine as salvage therapy in ACC.MethodsPatients registered with the German ACC Registry with refractory ACC progressing after cytotoxic therapies were offered treatment with bevacizumab (5 mg/kg body weight i.v. every 21 days) and oral capecitabine (950 mg/m2 twice daily for 14 days followed by 7 days of rest) in 2006–2008. Evaluation of tumour response was performed by imaging according to response evaluation criteria in solid tumours every 12 weeks.ResultsTen patients were treated with bevacizumab plus capecitabine. None of them experienced any objective response or stable disease. Two patients had to stop therapy after few weeks due to hand-foot syndrome, and three patients died on progressive disease within 12 weeks. Other adverse events were mild (grade I–II). Median survival after treatment initiation was 124 days.ConclusionsBevacizumab plus capecitabine has no activity in patients with very advanced ACC. Hence, this regimen cannot be recommended as a salvage therapy.
Clinical relevance of thyroid dysfunction in human haematopoiesis: biochemical and molecular studies
Authors: Kawa Miłosz Piotr , Grymuła Katarzyna , Paczkowska Edyta , Baśkiewicz-Masiuk Magdalena , Dąbkowska Elżbieta , Koziołek Monika , Tarnowski Maciej , Kłos Patrycja , Dziedziejko Violetta , Kucia Magdalena , Syrenicz Anhelli , Machaliński Bogusław 
Published: November 2009

ObjectiveAbnormalities in haematological parameters have been noted in patients with thyroid diseases. Nevertheless, the exact mechanism of thyroid hormones' (THs) action on human haematopoiesis is still not entirely clear.DesignThe influence of THs through TH receptors (TRα-1 and TRβ-1) on haematopoiesis in patients with hypo- and hyperthyroidism was analysed.MethodsTR gene expression at the mRNA and protein levels in human CD34+-enriched haematopoietic progenitor cells (HPCs) obtained from the peripheral blood of patients with thyroid disorders and healthy volunteers was analysed. The cell populations were also investigated for clonogenic growth of granulocyte macrophage-colony forming units and erythrocyte-burst forming units (BFU-E). The level of apoptosis was determined by annexin V/propidium iodide staining and quantitative RT-PCR.ResultsThe studies revealed that hypo- and hyperthyroidism modify TR gene expression in HPCs in vivo. TH deficiency resulted in a decrease in total blood counts and clonogenic potential of BFU-E. In contrast, hyperthyroid patients presented increased clonogenic growth and BFU-E number and significantly higher expressions of cell cycle-regulating genes such as those for PCNA and cyclin D1. Finally, an increase in the frequency of apoptotic CD34+-enriched HPCs in hypo- and hyperthyroidism with a modulation of apoptosis-related genes was detected.ConclusionsThe following conclusions were derived: i) TR expression in human haematopoietic cells depends on TH status, ii) both hypo- and hyperthyroidism significantly influence clonogenicity and induce apoptosis in CD34+-enriched HPCs and iii) the molecular mechanism by which THs influence haematopoiesis might provide a basis for designing novel therapeutic interventions in thyroid diseases.
Hypothalamic–pituitary–adrenal axis response to the severity of illness in non-critically ill patients: does relative corticosteroid insufficiency exist?
Authors: Michalaki M , Margeli T , Tsekouras A , Gogos C H , Vagenakis A G , Kyriazopoulou V 
Published: November 2009

ObjectiveRelative corticosteroid insufficiency may be common in critically ill patients and is associated with a poor outcome; however, the response of the hypothalamic–pituitary–adrenal (HPA) axis in nursed patients is not known. Our aim was to evaluate the response of HPA axis to the severity of illness in non-critically ill nursed (NCIN) patients and the clinical outcome.Subjects and methodsFifty-six nursed patients who were divided into four groups (stroke, mild disease, sepsis and severe sepsis) as well as a control group (n=15) were studied. At admission (day 1), cortisol and ACTH were measured and a low-dose (1 μg) corticotrophin test was performed, followed 2 h later by a standard-dose (250 μg) corticotrophin test. Diurnal variation of cortisol was obtained on day 2. A second identical set of low-dose and standard-dose corticotrophin tests were performed on day 5 or 6 (recovery phase).ResultsIn patients with stroke and severe sepsis, cortisol had the highest values and its diurnal variation was abolished. Dissociation of ACTH and cortisol was found in all patients.The Δmax of cortisol after the 1-μg corticotrophin test did not differ among the groups, while after the 250-μg corticotrophin test, it was borderline higher in controls. The ratio of responders (Δmax of cortisol ≥9 μg/dl) to non-responders after 1- or 250-μg corticotrophin test did not differ among patients and controls. All patients had a good outcome without glucocorticoid treatment.ConclusionsDepending on the severity of illness, mild alterations in the HPA axis occurred. However, relative corticosteroid insufficiency was not confirmed in NCIN patients.
THE BEARING CAPACITY OF SCREW PILES AND SCREWCRETE CYLINDERS.
Authors: WILSON G 
Published: November 2009

Summary This Paper describes an investigation which included model-experiments and full-scale loading tests on screw piles and cylinders, observations on the settlement of piles in actual structures, the derivation of a theory of bearing capacity, a check on the relationship between the driving torque and the bearing capacity of the pile, and the formulation of design rules. Two important factors, the first of which does not appear to have been appreciated previously, emerge from this investigation: they are that the value of the coefficient of earth-pressure at rest is a critical factor in the bearing capacity of structures founded in a frictional medium, and that the effect of screwing a cylinder with a closed nose into dense sand is to raise the horizontal earth-pressure considerably and so to effect a very large increase in the bearing capacity.
THE THERMAL EXPANSION OF CONCRETE. ENGINEERING RESEARCH. (SUMMARY OF A REPORT TO BE PUBLISHED BY THE BUILDING RESEARCH STATION).
Authors: BONNELL D G R , HARPER F C 
Published: November 2009

Synopsis Measurements of the coefficient of thermal expansion of different aggregates, and of concretes prepared from them with different cements, have been made over the temperature range 32°F. to 104°F. The values for aggregates have been found to range from 2.1 to 6.5 × l0-6 per °F. Siliceous materials have the highest coefficients, limestones the lowest, and igneous materials intermediate. Concretes have values in the range 3.4 to 7.3 × 10-6 per °F. The magnitude of the coefficient of expansion of concrete depends largely on the aggregate used; concretes with siliceous aggregate have the highest values and those with limestone aggregate the lowest, whilst concretes with igneous aggregate have intermediate values. The coefficient of thermal expansion of neat hydrated cement is higher than that of any aggregate measured. The richer mixes tend to have the higher thermal expansion but the order of difference is not high; the age of concrete has little effect on its thermal expansion. The method of curing and the water content have only a small influence on the thermal expansion. Desiccated and water-saturated concretes have similar coefficients of expansion but the values are lower than that of partly-dry concrete.
A Game Theoretic Approach to Conflicting and Evolving Stakeholder Preferences in the E&P Industry
Authors: Willigers B. J. A. , Bratvold R. B. , Hausken K. 
Published: November 2009

SummaryIn the high-risk E&P industry, the profit of each stakeholder depends on the strategies of all. The optimal choice for one player may not be optimal for other players, who may opt to prevent it. These characteristics suggest using game theory to model decision situations in the E&P industry. In a business dominated by joint ventures and tight governmental regulation, an understanding of the interests and influence of all stakeholders is particularly important. Although the E&P industry is accustomed to developing complex economic models to obtain insight into the commercial attractiveness of joint ventures, the influence of other stakeholders is often ignored. Each stakeholder must decide how much to invest, in which sequence to make decisions, whether to make decisions before or after the other stakeholders, which decisions to make before vs. after technological and organizational uncertainty is resolved, whether to accept or block the designation of one stakeholder as dominant, and whether to accept or block hub placement within one of multiple oil fields. A joint development program of a portfolio of gas fields and its gas processing and export facility has been analyzed using tools from game theory. The focus is on which infrastructure to develop and when. Players' preferences are functions of equity stakes and expected reserve sizes of the prospects. The analysis provides insight into the preferred development options of the individual players, how preferences change as uncertainty gets resolved, and how much individual players are to gain or lose if certain investment decisions are made. The analysis allows a player (1) to identify under what conditions its objectives are aligned with fellow players, and (2) to quantify the maximum amount it can pay to gain support from its fellow players.
Can Regression Discontinuity Help Answer an Age-Old Question in Education? The Effect of Age on Elementary and Secondary School Achievement
Authors: Smith Justin 
Published: November 2009

Abstract
Single-date school entry systems create large age differences between children in the same grade. Older students have been shown in the literature to outperform younger students along many elementary school outcomes, and some post-schooling outcomes. Little evidence exists about the size of these advantages in high school. Data from British Columbia, Canada are used to estimate the effect of age on test scores in grades 4, 7, and 10. I estimate that older students still have a sizable skill advantage in grade 10 across numeracy, reading, and writing tests. The advantage is strongest for girls and low-income students. The results suggest a certain degree of permanence to age related skill differences, which may spill over and affect adult outcomes.
Brain Drain and Brain Return: Theory and Application to Eastern-Western Europe
Authors: Mayr Karin , Peri Giovanni 
Published: November 2009

Abstract
This paper develops a novel model of optimal education, migration and return by heterogeneous, forward-looking agents. The model is parameterized and simulated to analyze the effects of immigration policies, identifying the brain-drain, brain-gain and brain-return effects when barriers to migration are reduced. We use parameters from the literature to inform our model and simulate migration and return from middle-income to industrialized countries. In particular, we apply the model to study migration and return between Eastern and Western Europe. We find that, for plausible degrees of openness, the possibility of return migration combined with the education incentive channel turns the brain drain into a brain gain for Eastern Europe.
Health System Reconstruction in Iraq ‐ The Way Ahead: A Report from the Iraq Health Symposium, May 20‐21, 2008
Authors: Tarantino David A , Morton Melinda J. , Kosaraju Akhila , Jawad Shakir , Casscells S. Ward 
Published: November 2009

AbstractHealth system stabilization and reconstruction support is a vital component of post‐conflict and disaster assistance efforts, and has been an essential component of overall reconstruction efforts in Iraq. However, decades of conflict, deprivation of key resources, mismanagement, sanctions, and a massive exodus of health care providers have exacted a grave toll on Iraq's health care capacity; furthermore, the health system continues to suffer from the impact of the ongoing insurgency and sectarian violence. Iraq's key public health indicators are among the worst in the region. In light of these pressing concerns, the humanitarian situation in Iraq presents a unique and ongoing challenge to the international community, aid agencies, and other key stakeholders. This symposium served as a forum for international leaders to review reconstruction efforts thus far and collaboratively plan future steps in Iraq's health system reconstruction.