bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phase structure and electrical properties of (Ba1/2Sr1/2)2+ modified high Curie temperature CaBi2Nb2O9‐based ceramics
Authors: Quan Liming , Zhang Biao , Chen Kaiyuan , Meng Yingzhi , Li Wangxin , Long Changbai , Fang Liang , Peng Biaolin , Chen Xue , Wang Dingyuan , Bai Yisong , da Silva Lucas Lemos , Liu Laijun 
Published: May 2024

AbstractHigh‐temperature piezoelectric sensing is usually used in the aerospace, automotive, and power plant fields. High temperature piezoelectric ceramics are considered the key materials in these fields. In this paper, Ca1−x(Ba1/2Sr1/2)xBi2Nb1.985(W3/4Mn1/4)0.015O9 (x = 0.05, 0.10, 0.15 and 0.20) (C1−xBSxBNWM) has been synthesized by a traditional solid state reaction method. The effects of substitution of calcium at the A‐site by barium and strontium on phase evolution and piezoelectric properties of the CaBi2Nb2O9 orthorhombic Aurivillius phases were investigated. The crystal structure of piezoelectric ceramics was characterized by XRD, Rietveld refinement, and Raman spectroscopy. Co‐substitution of barium/strontium (Ba2+/Sr2+) and tungsten/manganese (W6+/Mn4+) resulted in lattice distortion of C1−xBSxBNWM ceramics. The results induce that the tetragonal crystal structure increase with increasing the co‐substitution cations. Isothermal impedance spectroscopy confirmed intrinsic thermally activated conduction in the system. The C1−xBSxBNWM ceramics with x = 0.15 exhibit a very high Curie temperature (TC ∼ 923°C), a reasonable piezoelectric coefficient (d33 = 13.3 pC/N). Remarkably, even after thermal annealing at temperatures up to 800°C, it still retains a high d33 of 13 pC/N. In addition, the C0.85BS0.15BNWM ceramic had a relatively high resistivity (3.82 × 106 Ω·cm, 500°C). The Ca0.85(Ba1/2Sr1/2)0.15Bi2Nb1.985(W3/4Mn1/4)0.015O9 ceramics make possible their application in high‐temperature acceleration transducers.
Simultaneously realizing high energy density and high efficiency in NaNbO3–BaTiO3‐based ceramic capacitors
Authors: Lu Ye , Zhang Ji , Zhao Xinyi , Zhou Kedong , He Lei 
Published: May 2024

AbstractDielectric capacitors, which can achieve tremendous power density and ultrafast charge/discharge speed, are crucial components for high power equipment. Yet, the synchronous achievement in high recoverable energy density (Wrec) and high efficiency (η) is a long‐term difficulty for dielectric ceramics. Herein, the (0.85 − x)NaNbO3–0.15BaTiO3–xBi(Mg1/3Ta2/3)O3 (NN–BT–xBMT) relaxor ferroelectric ceramics were proposed and studied. The doping of BMT was conducive to promoting the microstructure and bandgap and improving the dielectric relaxation properties of NN–BT ceramics. Finally, the sample of x = 0.10 presented a high Wrec of 5.9 J/cm3 and a high η of 90% simultaneously. In addition, the sample also exhibited superb charge/discharge performances with large power density (PD = 137 MW/cm3) and fast charge/discharge speed (t0.9 = 39 ns). The above results reveal that the NaNbO3‐based ceramics could serve as potential alternatives for advanced dielectric capacitors.
ANGPTL2 knockdown induces autophagy to relieve alveolar macrophage pyroptosis by reducing LILRB2‐mediated inhibition of TREM2
Authors: Yang Fan , Chen Muhu , Liu Ying , Hu Yingchun , Chen Yangxi , Yu Youwei , Deng Lu 
Published: May 2024

AbstractAcute lung injury (ALI) is featured with a robust inflammatory response. Angiopoietin‐like protein 2 (ANGPTL2), a pro‐inflammatory protein, is complicated with various disorders. However, the role of ANGPTL2 in ALI remains to be further explored. The mice and MH‐S cells were administrated with lipopolysaccharide (LPS) to evoke the lung injury in vivo and in vitro. The role and mechanism of ANGPTL was investigated by haematoxylin–eosin, measurement of wet/dry ratio, cell count, terminal deoxynucleotidyl transferase deoxyuridine triphosphate (dUTP) nick end labeling, reverse transcription quantitative polymerase chain reaction, immunofluorescence, enzyme‐linked immunosorbent assay, detection of autophagic flux and western blot assays. The level of ANGPTL2 was upregulated in lung injury. Knockout of ANGPTL2 alleviated LPS‐induced pathological symptoms, reduced pulmonary wet/dry weight ratio, the numbers of total cells and neutrophils in BALF, apoptosis rate and the release of pro‐inflammatory mediators, and modulated polarization of alveolar macrophages in mice. Knockdown of ANGPTL2 downregulated the level of pyroptosis indicators, and elevated the level of autophagy in LPS‐induced MH‐S cells. Besides, downregulation of ANGPTL2 reversed the LPS‐induced the expression of leukocyte immunoglobulin (Ig)‐like receptor B2 (LILRB2) and triggering receptor expressed on myeloid cells 2 (TREM2), which was reversed by the overexpression of LILRB2. Importantly, knockdown of TREM2 reversed the levels of autophagy‐ and pyroptosis‐involved proteins, and the contents of pro‐inflammatory factors in LPS‐induced MH‐S cells transfected with si ANGPTL2, which was further inverted with the treatment of rapamycin. Therefore, ANGPTL2 silencing enhanced autophagy to alleviate alveolar macrophage pyroptosis via reducing LILRB2‐mediated inhibition of TREM2.
Influence of temperature on hatching success of skipjack tuna (Katsuwonus pelamis): Implications for spawning availability of warm habitats
Authors: Fujioka Ko , Aoki Yoshinori , Tsuda Yuichi , Okamoto Kei , Tsuchida Hiroyuki , Sasaki Akira , Kiyofuji Hidetada 
Published: May 2024

AbstractExploring the effects of water temperature on egg development in skipjack tuna (Katsuwonus pelamis) has substantial implications for evaluations of wild spawning habitats. In the present study, we examined the hatching success and duration as a function of temperature from 21 to 33°C under captive environments. A high hatching rate of over 50% between 23 and 31°C was observed, with the shortest hatching duration at 31°C. Because the egg period is vulnerable to predators, a shortened hatching duration with warming water would be ecologically advantageous for K. pelamis, as its main spawning grounds are located in tropical areas.
Physical therapy in addition to occlusal splint in myogenic temporomandibular disorders: A randomised controlled trial
Authors: Romeo Antonio , Incorvati Cristina , Vanti Carla , Turolla Andrea , Marinelli Francesco , Defila Luca , Gulotta Chiara , Marchetti Claudio , Pillastrini Paolo 
Published: May 2024

AbstractBackgroundMyogenic temporomandibular disorders (M‐TMD) commonly involve occlusal splint (OS) therapy and musculoskeletal physiotherapy (MPT).ObjectivesTo compare the effects of combining OS with MPT and education (EG) against OS and education (CG), in chronic M‐TMD patients.MethodsIn this double‐blind randomised controlled trial, 62 participants were assigned to either EG or CG. The primary outcomes, pain levels at rest (VAS rest), maximum oral opening (VAS open) and during chewing (VAS chew), were measured by Visual Analogue Scale (VAS) in cm. The secondary outcome was the range of motion (ROM) for maximum oral opening. Both interventions lasted 3 months, with outcomes assessed at baseline (T0), post‐treatment (T1) and 3 months post‐treatment (T2).ResultsIntention‐to‐treat analysis revealed significant improvements favouring EG (VAS rest = −1.50 cm [CI95%: −2.67, −0.32], p = .04; VAS open = −2.00 cm [CI95%: −3.23, −0.75], p < .01; VAS chew = −1.71 cm [CI95%: −2.90, −0.52], p = .01; ROM = 4.61 [CI95%: 0.93, 8.30], p = .04). Additionally, VAS measures were influenced by follow‐up times (VAS rest = −0.73 cm [CI95%: −1.30, −0.17], p = 0.03; VAS open = −0.97 cm [CI95%: −1.57, −0.37], p < .01; VAS chew = −1.15 cm [CI95%: −1.73, −0.58], p < .01). At T1, EG demonstrated higher number of responders compared to CG for VAS open (χ2(1) = 4.39, p = .04) and VAS chew (χ2(1) = 11.58, p < .01).ConclusionAdding MPT to education and OS yields better outcomes in terms of pain reduction and ROM improvement, in chronic M‐TMD.Trial Registration NumberNCT03726060.
Cost‐effectiveness of nasal high‐flow in children with acute hypoxaemic respiratory failure
Authors: Gannon Brenda , Franklin Donna , Vo Vinh , Babl Franz E , Schibler Andreas 
Published: May 2024

AimA pilot randomised controlled trial assessed the early application of nasal high‐flow (NHF) therapy compared with standard oxygen therapy (SOT), in children aged 0 to 16 years presenting to paediatric emergency departments with acute hypoxaemic respiratory failure (AHRF). The study estimated the need to escalate therapy and hospital length of stay in the NHF group compared with SOT. This sub‐study then assessed the subsequent cost‐effectiveness.MethodsA decision tree‐based model was developed, alongside the clinical study, to estimate cost‐effectiveness, from the healthcare sector perspective. The primary health economics outcome is measured as incremental cost per length of hospital stay avoided. Incremental cost effectiveness ratios (ICER) measuring change in cost per change in length of stay, were obtained for four samples, depending on responder status and obstructive airways disease. These were (1) obstructive and responder, (2) non‐obstructive and responder, (3) obstructive and non‐responder and (4) non obstructive and non‐responder. Bootstrapping of parameters accounted for uncertainty in estimates of cost and outcome.ResultsThe ICER for patients randomised to NHF, indicated an additional A$367.20 for a lower hospital length of stay (in days) in the non‐obstructive/non‐responder sample. In the bootstrap sample, this was found to be cost effective above a willingness to pay threshold of A$10 000. The ICER was A$440.86 in the obstructive/responder sample and A$469.56 in the non‐obstructive/responder sample – but both resulted in a longer length of stay. The ICER in the obstructive/non‐responder sample was A$52 167.76, also with a longer length of stay, mainly impacted by a small sample of severe cases.ConclusionAs first‐line treatment, NHF is unlikely to be cost‐effective compared with SOT, but for non‐obstructive patients who required escalation in care (non‐obstructive non‐responder), NHF is likely to be cost‐effective if willingness‐to‐pay per reduced hospital length of stay is more than A$10 000 per patient.
Photosynthate transfer from an autotrophic orchid to conspecific heterotrophic protocorms through a common mycorrhizal network
Authors: Read David J. , Haggar John , Magkourilou Emily , Durant Emily , Johnson David , Leake Jonathan R. , Field Katie J. 
Published: May 2024

Summary

The minute ‘dust seeds’ of some terrestrial orchids preferentially germinate and develop as mycoheterotrophic protocorms near conspecific adult plants. Here we test the hypothesis that mycorrhizal mycelial connections provide a direct pathway for transfer of recent photosynthate from conspecific green orchids to achlorophyllous protocorms.

Mycelial networks of Ceratobasidium cornigerum connecting green Dactylorhiza fuchsii plants with developing achlorophyllous protocorms of the same species were established on oatmeal or water agar before the shoots of green plants were exposed to 14CO2. After incubation for 48 h, the pattern of distribution of fixed carbon was visualised in intact entire autotrophic/protocorm systems using digital autoradiography and quantified in protocorms by liquid scintillation counting.

Both methods of analysis revealed accumulation of 14C above background levels in protocorms, confirming that autotrophic plants supply carbon to juveniles via common mycorrhizal networks. Despite some accumulation of plant‐fixed carbon in the fungal mycelium grown on oatmeal agar, a greater amount of carbon was transferred to protocorms growing on water agar, indicating that the polarity of transfer may be influenced by sink strength.

We suggest this transfer pathway may contribute significantly to the pattern and processes determining localised orchid establishment in nature, and that ‘parental nurture’ via common mycelial networks may be involved in these processes.
Evolutionary pathways to lower biomass allocation to the seed coat in crops: insights from allometric scaling
Authors: Milla Rubén , Westgeest Adrianus J. , Maestre‐Villanueva Jorge , Núñez‐Castillo Sergio , Gómez‐Fernández Alicia , Vasseur François , Violle Cyrille , Balarynová Jana , Smykal Petr 
Published: May 2024

Summary

Crops generally have seeds larger than their wild progenitors´ and with reduced dormancy. In wild plants, seed mass and allocation to the seed coat (a proxy for physical dormancy) scale allometrically so that larger seeds tend to allocate less to the coats. Larger seeds and lightweight coats might thus have evolved as correlated traits in crops.

We tested whether 34 crops and 22 of their wild progenitors fit the allometry described in the literature, which would indicate co‐selection of both traits during crop evolution. Deviations from the allometry would suggest that other evolutionary processes contribute to explain the emergence of larger, lightweight‐coated seeds in crops.

Crops fitted the scaling slope but deviated from its intercept in a consistent way: Seed coats of crops were lighter than expected by their seed size. The wild progenitors of crops displayed the same trend, indicating that deviations cannot be solely attributed to artificial selection during or after domestication.

The evolution of seeds with small coats in crops likely resulted from a combination of various pressures, including the selection of wild progenitors with coats smaller than other wild plants, further decreases during early evolution under cultivation, and indirect selection due to the seed coat‐seed size allometry.
The delivery and challenges of Pediatric Anesthesia within the humanitarian sector: Médecins Sans Frontières and Mercy Ships
Authors: Holt Francesca , Kwok Sarah , Garuba Kehinde , Kolawole Israel , White Michelle C. 
Published: May 2024

AbstractAccess to healthcare is inequitable. Poverty, natural disasters and war disproportionally effect those most vulnerable, including children. Non‐governmental organizations (NGO) hold a vital role in providing pediatric care in these contexts. Here we describe the delivery and challenges of Pediatric Anesthesia with two such non‐governmental organizations; Médecins Sans Frontières (MSF) and Mercy Ships. Descriptions of both are followed by case studies.
Public health nurse perspectives on predicting nonattendance for cervical cancer screening through classification, ensemble, and deep learning models
Authors: Devi Seeta , Gangarde Rupali , Deokar Shubhangi , Muqeemuddin Sayyed Faheemuddin , Awasthi Sanidhya Rajendra , Shekhar Sameer , Sonchhatra Raghav , Joshi Sonopant 
Published: May 2024

AbstractObjectivesWomen's attendance to cervical cancer screening (CCS) is a major concern for healthcare providers in community. This study aims to use the various algorithms that can accurately predict the most barriers of women for nonattendance to CS.DesignThe real‐time data were collected from women presented at OPD of primary health centers (PHCs). About 1046 women's data regarding attendance and nonattendance to CCS were included. In this study, we have used three models, classification, ensemble, and deep learning models, to compare the specific accuracy and AU‐ROC for predicting non‐attenders for CC.ResultsThe current model employs 22 predictors, with soft voting in ensemble models showing slightly higher specificity (96%) and sensitivity (93%) than weighted averaging. Bagging excels with the highest accuracy (98.49%), specificity (97.3%), and ideal sensitivity (100%) with an AUC of 0.99. Classification models reveal Naive Bayes with higher specificity (97%) but lower sensitivity (91%) than Logistic Regression. Random Forest and Neural Network achieve the highest accuracy (98.49%), with an AUC of 0.98. In deep learning, LSTM has an accuracy of 95.68%, higher specificity (97.60%), and lower sensitivity (93.42%) compared to other models. MLP and NN showed the highest AUC values of 0.99.ConclusionEmploying ensemble and deep learning models proved most effective in predicting barriers to nonattendance in cervical screening.
Torn between living or dying—analyses of influencing factors on suicide ambivalence and its longitudinally impact on suicidal ideation and behavior in a high‐risk sample
Authors: Höller Inken , Forkmann Thomas , Glaesmer Heide , Teismann Tobias , Spangenberg Lena , Schreiber Dajana , Hallensleben Nina , Kraiss Jannis 
Published: May 2024

AbstractIntroductionFindings on the role of suicide ambivalence, an individual's wish to live (WL), and wish to die (WD) in the development of suicidality have been heterogenous. The main goal of this study was to examine associations of these constructs within the past week with sociodemographic factors and to longitudinally investigate their predictive power for suicidal ideation (SI) and suicide attempts (SA).MethodsN = 308 patients (54% female; M = 36.92 years, SD = 14.30), admitted to a psychiatric ward due to suicidality, were assessed for all constructs after admission, after six, nine, and 12 months. Data were analyzed with univariate fixed‐effect models and lagged mixed‐effect regression models.ResultsDecreased, WL increased post‐baseline. Gender showed no significant link to ambivalence, WD, and WL. Ambivalence and WD correlated negatively with age and positively with depressiveness. More participants in a relationship showed a WL compared with single/divorced/widowed participants. More single participants or those in a relationship showed ambivalence than divorced/widowed participants. More single participants showed a WD than participants in a relationship/divorced/widowed. Longitudinally, ambivalence and WD predicted SI and SA.ConclusionThe findings underscore the importance of taking suicide ambivalence and WD into account in risk assessment and treatment.
Osteosarcoma with widespread metastasis in a 1‐year‐old crossbred rabbit
Authors: Lye Gordon , Dittmer Keren , Pemberton Sarah , Lockhart Kezia , Pollard Rachel 
Published: May 2024

AbstractA 14‐month‐old female spayed, small crossbred rabbit presented for assessment of a small, hard subcutaneous nodule in the right axilla. Serum biochemistry showed markedly increased serum ALP activity. A whole‐body CT revealed an aggressive, monostotic osteolytic, and productive lesion within the left alveolar process of the maxilla, with erosion of the alveolar bone and secondary premolar depression. Innumerable metastatic osseous masses were present throughout the body, including cerebral, pulmonary, hepatic, subcutaneous, and skeletal muscular metastases. Postmortem findings confirmed widespread, metastatic osteosarcoma, with the primary lesion within the left maxilla.
Phenotypic amikacin resistance may not indicate poor response to amikacin in
Mycobacterium avium
complex pulmonary disease
Authors: Minuk L. M. , Brode S. K. , Mehrabi M. , Sharma M. K. , Stobart M. , Soualhine H. , Marras T. K. 
Published: May 2024

ABSTRACT

When using amikacin to treat
Mycobacterium avium
complex pulmonary disease (MAC-PD), a minimum inhibitory concentration resistance breakpoint of ≥64 mcg/mL is recommended. We explored whether amikacin resistance characterized by phenotypic drug susceptibility testing was associated with clinical outcomes or mutational resistance in a retrospective cohort of patients with MAC-PD. Despite little aminoglycoside exposure, amikacin resistance was common in our MAC-PD patients but was not associated with worse outcomes or
rrs
gene mutations.
Parascedosporium putredinis
NO1 tailors its secretome for different lignocellulosic substrates
Authors: Scott Conor J. R. , McGregor Nicholas G. S. , Leadbeater Daniel R. , Oates Nicola C. , Hoßbach Janina , Abood Amira , Setchfield Alexander , Dowle Adam , Overkleeft Herman S. , Davies Gideon J. , Bruce Neil C. 
Published: May 2024

ABSTRACT

Parascedosporium putredinis
NO1 is a plant biomass-degrading ascomycete with a propensity to target the most recalcitrant components of lignocellulose. Here we applied proteomics and activity-based protein profiling (ABPP) to investigate the ability of
P. putredinis
NO1 to tailor its secretome for growth on different lignocellulosic substrates. Proteomic analysis of soluble and insoluble culture fractions following the growth of
P. putredinis
NO1 on six lignocellulosic substrates highlights the adaptability of the response of the
P. putredinis
NO1 secretome to different substrates. Differences in protein abundance profiles were maintained and observed across substrates after bioinformatic filtering of the data to remove intracellular protein contamination to identify the components of the secretome more accurately. These differences across substrates extended to carbohydrate-active enzymes (CAZymes) at both class and family levels. Investigation of abundant activities in the secretomes for each substrate revealed similar variation but also a high abundance of “unknown” proteins in all conditions investigated. Fluorescence-based and chemical proteomic ABPP of secreted cellulases, xylanases, and β-glucosidases applied to secretomes from multiple growth substrates for the first time confirmed highly adaptive time- and substrate-dependent glycoside hydrolase production by this fungus.
P. putredinis
NO1 is a promising new candidate for the identification of enzymes suited to the degradation of recalcitrant lignocellulosic feedstocks. The investigation of proteomes from the biomass bound and culture supernatant fractions provides a more complete picture of a fungal lignocellulose-degrading response. An in-depth understanding of this varied response will enhance efforts toward the development of tailored enzyme systems for use in biorefining.

IMPORTANCE

The ability of the lignocellulose-degrading fungus
Parascedosporium putredinis
NO1 to tailor its secreted enzymes to different sources of plant biomass was revealed here. Through a combination of proteomic, bioinformatic, and fluorescent labeling techniques, remarkable variation was demonstrated in the secreted enzyme response for this ascomycete when grown on multiple lignocellulosic substrates. The maintenance of this variation over time when exploring hydrolytic polysaccharide-active enzymes through fluorescent labeling, suggests that this variation results from an actively tailored secretome response based on substrate. Understanding the tailored secretomes of wood-degrading fungi, especially from underexplored and poorly represented families, will be important for the development of effective substrate-tailored treatments for the conversion and valorization of lignocellulose.