bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endovascular management of inadvertent brachiocephalic arterial catheterization
Authors: Powers Ciaran J. , Zomorodi Ali R. , Britz Gavin W. , Enterline David S. , Miller Michael J. , Smith Tony P. 
Published: November 2009

Object
Inadvertent catheterization of brachiocephalic arteries (carotid artery, subclavian artery, or vertebral artery) during attempted placement of a central venous catheter can have potentially disastrous complications. While removal of the catheter in the operating room is almost always an option, there are circumstances in which a less invasive approach may be more appropriate. The authors present their experience using endovascular techniques for removal of inadvertently placed central venous catheters to elucidate potential options for successful nonsurgical management.

Methods
The authors reviewed their database of interventional procedures that occurred between January 1, 2000, and February 1, 2009. All cases referred for management of suspected brachiocephalic arterial catheterization or arterial injury after attempted placement of a central venous catheter were included. Medical records and radiological imaging were reviewed to determine patient demographics, clinical situation, methods for removal, as well as clinical and imaging follow-up.

Results
A total of 13 patients, ranging in age from 31 to 88 years old, were referred to interventional radiology for management of suspected inadvertent arterial catheterization of the brachiocephalic arteries. Angiography confirmed arterial catheterization in 9 patients. Three patients were referred after developing uncontrolled hemorrhage or expanding hematomas following attempted catheterization. One patient who had an arterial waveform after placement of an internal jugular catheter was found to have early venous filling from a dialysis fistula requiring no intervention. Ten patients were treated in the interventional suite using angiographically monitored manual pressure (1 patient), balloon tamponade (3 patients), use of a percutaneous closure device (1 patient), stent grafting (4 patients), or embolization of the injured vessel alone (1 patient). One patient was taken to the operating room for removal of the inadvertently placed catheter due to vessel thrombosis. No procedural complications were encountered, and no patient required sacrifice of a major brachiocephalic vessel.

Conclusions
Angiographic evaluation of patients who underwent inadvertent catheterization of brachiocephalic arteries or their branches allowed successful endovascular treatment or excluded the need for intervention in 12 (92%) of 13 patients. The choice and use of specific endovascular techniques should be dictated by patient factors and the vessel inadvertently catheterized.
Interaction of neurovascular protection of erythropoietin with age, sepsis, and statin therapy following aneurysmal subarachnoid hemorrhage
Authors: Tseng Ming-Yuan , Hutchinson Peter J. , Kirkpatrick Peter J. 
Published: November 2009

Object
In a previous randomized controlled trial, the authors demonstrated that acute erythropoietin (EPO) therapy reduced severe vasospasm and delayed ischemic deficits (DIDs) following aneurysmal subarachnoid hemorrhage. In this study, the authors aimed to investigate the potential interaction of neurovascular protection by EPO with age, sepsis, and concurrent statin therapy.

Methods
The clinical events of 80 adults older than 18 years and with < 72 hours of aneurysmal subarachnoid hemorrhage, who were randomized to receive 30,000 U of intravenous EPO-β or placebo every 48 hours for a total of 3 doses, were analyzed by stratification according to age (< or ≥ 60 years), sepsis, or concomitant statin therapy. End points in the trial included cerebral vasospasm and impaired autoregulation on transcranial Doppler ultrasonography, DIDs, and unfavorable outcome at discharge and at 6 months measured with the modified Rankin Scale and Glasgow Outcome Scale. Analyses were performed using the t-test and/or ANOVA for repeated measurements.

Results
Younger patients (< 60 years old) or those without sepsis obtained benefits from EPO by a reduction in vasospasm, impaired autoregulation, and unfavorable outcome at discharge. Compared with nonseptic patients taking EPO, those with sepsis taking EPO had a lower absolute reticulocyte count (nonsepsis vs sepsis, 143.5 vs. 105.8 × 109/L on Day 6; p = 0.01), suggesting sepsis impaired both hematopoiesis and neurovascular protection by EPO. In the EPO group, none of the statin users suffered DIDs (p = 0.078), implying statins may potentiate neuroprotection by EPO.

Conclusions
Erythropoietin-related neurovascular protection appears to be attenuated by old age and sepsis and enhanced by statins, an important finding for designing Phase III trials.
A comparison of video and static photo lineups with child and adolescent witnesses
Authors: Havard Catriona , Memon Amina , Clifford Brian , Gabbert Fiona 
Published: November 2009

AbstractIn the UK video parades are the preferred method of identification employed in criminal cases. This policy implementation has been employed with little or no evidence concerning its validity. The reported research examines the effect of new video technology on children's identification evidence. The study compared 7–9 and 13–15‐year olds' ability to make identifications from either video or static photo lineups. Two hundred and fifteen participants witnessed a live event and then after a delay of 2–3 days viewed a target present (TP), or target absent (TA) video or photo lineup. For video and photo TP lineups, correct responses did not differ as a function of age. Video lineups produced lower rates of false identifications for the TA lineups, but only for adolescent witnesses. It is concluded that there is nothing contra‐indicated in the use of video identification procedures with children, and possibly certain benefits can accrue from its use. Copyright © 2009 John Wiley & Sons, Ltd.
Clean and Flexible Modification Strategy for Carboxyl/Aldehyde‐Functionalized Upconversion Nanoparticles and Their Optical Applications
Authors: Zhou Huan‐Ping , Xu Chun‐Hu , Sun Wei , Yan Chun‐Hua 
Published: November 2009

AbstractRare‐earth upconversion nanoparticles (UCNPs) exhibit great potential in luminescent biolabels and other multifunctional probes; however, their applications are limited by their low water solubility and the lack of binding groups. To address these problems, a clean and flexible strategy to modify hydrophobic monodisperse UCNPs into hydrophilic ones that are capped with functional groups is developed. The modification process is implemented by direct oxidation of oleic acid ligands with ozone under specific conditions, where the oleic acid (OA) ligands on the surface of the UCNPs can be converted into azelaic acid ligands (HOOC(CH2)7COOH) or azelaic aldehyde HOOC(CH2)7CHO, as is revealed by Fourier‐transform infrared (FTIR) and nuclear magnetic resonance (NMR) measurements. This oxidation process has no significant side‐effects on the morphology, phase, composition, or luminescent properties of the UCNPs. Free carboxylic acid groups on the surface endow the UCNPs with good water solubility, while aldehyde groups at the surface provide binding sites for amino‐containing molecules via Schiff‐base condensation, such as 2‐(4‐aminophenylethylyl)‐5‐methoxy‐2‐(2‐pyridyl)thiazole (MPTEA) and 2‐aminoethanethiol hydrochloride (NH2CH2CH2SH·HCl, HEMA). A Ce4+ sensor is constructed based on the dual‐emission arising from the different spectral responses of MPTEA and the UCNPs. Facilitated by the covalent linkage between the terminal aldehyde group on the UCNPs and the amino group in HEMA, a hybrid structure of UCNPs and Au NPs is fabricated. The effective coupling between the aldehyde group and the amino group suggests that these functionalized UCNPs have potential in combining other functional units for simultaneous biolabeling, or other optical applications.
Specific Functionalization of Carbon Nanotubes for Advanced Polymer Nanocomposites
Authors: Sahoo Nanda Gopal , Cheng Henry Kuo Feng , Li Lin , Chan Siew Hwa , Judeh Zaher , Zhao Jianhong 
Published: November 2009

AbstractA novel approach to chemically functionalize multiwalled carbon nanotubes (MWCNTs) for making advanced polymeric nanocomposites with liquid crystalline polymers (LCPs) is presented. In this approach, two types of chemical moieties (i.e., carboxylic and hydroxyl benzoic acid groups) are selectively introduced onto the sidewalls of the MWCNTs. Fourier transform IR and Raman spectroscopy are used to examine the interaction between the functionalized MWCNTs and the LCP. The strong interaction between the functionalized MWCNTs and the LCP greatly improved the dispersion of MWCNTs in the polymer matrix as well as the interfacial adhesion. The dispersion of the MWCNTs in the LCP matrix is observed by optical microscopy and field‐emission scanning electron microscopy. As a result, the addition of 1 wt% MWCNTs in the LCP resulted in the significant improvement (41 and 55%) in the tensile strength and modulus of the LCP.
Oral health and frailty in the medieval English cemetery of St Mary Graces
Authors: DeWitte Sharon N. , Bekvalac Jelena 
Published: November 2009

AbstractThe analysis of oral pathologies is routinely a part of bioarcheological and paleopathological investigations. Oral health, while certainly interesting by itself, is also potentially informative about general or systemic health. Numerous studies within modern populations have shown associations between oral pathologies and other diseases, such as cardiovascular disease, certain types of cancer, and pulmonary infections. This article addresses the question of how oral health was associated with general health in past populations by examining the relationship between two oral pathologies (periodontal disease and dental caries) and the risk of mortality in a cemetery sample from medieval England. The effects of periodontitis and dental caries on risk of death were assessed using a sample of 190 individuals from the St Mary Graces cemetery, London, dating to ∼AD 1350–1538. The results suggest that the oral pathologies are associated with elevated risks of mortality in the St Mary Graces cemetery such that individuals with periodontitis and dental caries were more likely to die than their peers without such pathologies. The results shown here suggest that these oral pathologies can be used as informative indicators of general health in past populations. Am J Phys Anthropol, 2010. © 2009 Wiley‐Liss, Inc.
Solid state and proton relaxation NMR study ofDipteryx alataVogel
Authors: Maciel Paula de Miranda Costa , Tavares Maria Inês Bruno 
Published: November 2009

AbstractThe knowledge of polysaccharides obtained from fruit seed and its chemical characteristics are important to evaluate their final properties, as well as their uses and benefits. Solid state nuclear magnetic resonance (NMR) has been used to evaluate the behavior of the samples, since NMR permits to evaluate both chemical and dynamic molecular behavior of polysaccharides, because they are amorphous and heterogeneous. The NMR analyzes were carried out using high and low field NMR techniques. The results obtained from high field showed the main chemical constituents present in the seeds and seed flour. Through low field NMR different domains with their own molecular mobility and interactions were observed; due to the measurements of proton spin‐lattice relaxation time (T1H). According to the results obtained for Cumbaru seed, solid state NMR showed to be a powerful source to characterize fruit seed flour. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Inhibition of the thermal degradation of rigid poly(vinyl chloride) using poly(N‐[4‐(N′‐phenyl amino carbonyl)phenyl]maleimide)
Authors: Fahmy Mona Mohamed 
Published: November 2009

AbstractPoly(N‐[4‐(N′‐phenyl amino carbonyl)phenyl]maleimide), poly(PhPM), has been investigated for the inhibition of the thermal degradation of rigid poly(vinyl chloride) (PVC) in air, at 180°C. Its stabilizing efficiency was evaluated by measuring the length of the induction period, the period during which no detectable amounts of hydrogen chloride gas could be observed, and also from the rate of dehydrochlorination as measured by continuous potentiometric determination, and the extent of discoloration of the degraded polymer. The results have proved the greater stabilizing efficiency of poly(PhPM) relative to that of the DBLC commercial stabilizer. This is well demonstrated by the longer induction period values and by the lower rates both of dehydrochlorination and discoloration of the polymer during degradation relative to those of the DBLC reference stabilizer. The greater stabilizing efficiency of the poly(PhPM) is most probably attributed not only to its possession of various centers of reactivity that can act as traps for radical species resulting during the degradation process, and replacement of labile chlorine atoms on PVC chains by relatively more thermally stable poly(PhPM) moieties, but also due to the ability of its fragmentation products to react with the evolved hydrogen chloride gas. A radical mechanism is suggested to account for the stabilizing action of this polymeric stabilizer. A synergistic effect is achieved when the poly(PhPM) was blended in various weight ratios with DBLC. This synergism attains its maximum when poly(PhPM) and DBLC are taken at 3 : 1 weight ratio. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Shape‐memory property and characterization of epoxy resin‐modified Mesua ferrea L. seed oil‐based hyperbranched polyurethane
Authors: Deka Harekrishna , Karak Niranjan 
Published: November 2009

AbstractModification of existing polymers leads to enhancement of many desirable properties. So, a hyperbranched polyurethane (HBPU) of monoglyceride of Mesua ferrea L. seed oil, poly(ε‐caprolactone)diol (Mn = 3000 g mol−1), 2,4‐toluene diisocyanate, and glycerol with 30% hard segment (NCO/OH = 0.96) has been modified with different amounts of bisphenol‐A based epoxy resin. The system is cured by poly(amido amine) hardener at 120°C for specified period of time. Improvement of thermostability, scratch hardness, and impact strength are observed by this modification of HBPU. The differential scanning calorimetry (DSC) results show improvement of melting temperature of the modified systems. The enhancement of tensile strength is about 2.4 times compared with that of the unmodified one. The morphology and structural changes due to variation of epoxy content was studied by scanning electron microscopy (SEM) analysis and Fourier transform infrared (FTIR) spectroscopy. The rheological properties of the epoxy‐modified HBPU show the dependence on the amount of epoxy resin. Shape memory study of the crosslinked HBPUs shows 90–98% thermoresponsive shape recovery. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
The foundation of the concept of relevance
Authors: Hjørland Birger 
Published: November 2009

AbstractIn 1975 Tefko Saracevic declared “the subject knowledge view” to be the most fundamental perspective of relevance. This paper examines the assumptions in different views of relevance, including “the system's view” and “the user's view” and offers a reinterpretation of these views. The paper finds that what was regarded as the most fundamental view by Saracevic in 1975 has not since been considered (with very few exceptions). Other views, which are based on less fruitful assumptions, have dominated the discourse on relevance in information retrieval and information science. Many authors have reexamined the concept of relevance in information science, but have neglected the subject knowledge view, hence basic theoretical assumptions seem not to have been properly addressed. It is as urgent now as it was in 1975 seriously to consider “the subject knowledge view” of relevance (which may also be termed “the epistemological view”). The concept of relevance, like other basic concepts, is influenced by overall approaches to information science, such as the cognitive view and the domain‐analytic view. There is today a trend toward a social paradigm for information science. This paper offers an understanding of relevance from such a social point of view.
Hypothesis: Could Epstein‐Barr virus play a role in the development of gastroschisis?
Authors: Werler Martha M. 
Published: November 2009

AbstractBACKGROUND:The strong inverse association between maternal age and risk of gastroschisis in offspring has spurred many investigators to hypothesize that behaviors among younger females are the cause. Examples include cigarette smoking, illicit drugs, genitourinary infections, and sexually transmitted diseases, each of which has been reported to be associated with gastroschisis. Although these exposures are more common in young women, recent studies have shown that cigarette smoking, genitourinary infections, and sexually transmitted diseases are most strongly associated with gastroschisis in older women. There is both anecdotal and published evidence showing that gastroschisis sometimes (but not always) occurs in clusters, raising the possibility that an infectious agent might be involved in its pathogenesis.RESULTS:One such agent whose epidemiologic characteristics parallel those of gastroschisis is Epstein‐Barr virus (EBV). Primary EBV infection in early childhood has been decreasing over time, leaving a greater proportion of adolescents at risk, as reflected by increased rates of infectious mononucleosis over time. During the childbearing years, risk of primary EBV infection decreases dramatically, as does risk of gastroschisis. The stronger risks of gastroschisis associated with cigarette smoking, genitourinary infections, and sexually transmitted diseases in older women might be explained by EBV reactivation resulting from multiple challenges to immune response such as pregnancy, age, toxic exposures, and genitourinary and sexually transmitted infections.CONCLUSION:EBV and other herpes viruses should be added to the research agenda for gastroschisis. Birth Defects Research (Part A) 2010. © 2009 Wiley‐Liss, Inc.
A New Class of Modular P,N‐Ligand Library for Asymmetric Pd‐Catalyzed Allylic Substitution Reactions: A Study of the Key Pd–π‐Allyl Intermediates
Authors: Mazuela Javier , Paptchikhine Alexander , Tolstoy Päivi , Pàmies Oscar , Diéguez Montserrat , Andersson Pher G. 
Published: November 2009

AbstractA new class of modular P,N‐ligand library has been synthesized and screened in the Pd‐catalyzed allylic substitution reactions of several substrate types. These series of ligands can be prepared efficiently from easily accessible hydroxyl–oxazole/thiazole derivatives. Their modular nature enables the bridge length, the substituents at the heterocyclic ring and in the alkyl backbone chain, the configuration of the ligand backbone, and the substituents/configurations in the biaryl phosphite moiety to be easily and systematically varied. By carefully selecting the ligand components, therefore, high regio‐ and enantioselectivities (ee values up to 96 %) and good activities are achieved in a broad range of mono‐, di‐, and trisubstituted linear hindered and unhindered substrates and cyclic substrates. The NMR spectroscopic and DFT studies on the Pd–π‐allyl intermediates provide a deeper understanding of the effect of ligand parameters on the origin of enantioselectivity.
The impact of health insurance status on the survival of patients with head and neck cancer
Authors: Kwok Joseph , Langevin Scott M. , Argiris Athanassios , Grandis Jennifer R. , Gooding William E. , Taioli Emanuela 
Published: November 2009

AbstractBACKGROUND:In 2006, it was estimated that 47 million people in the United States are without insurance. Studies have shown that patients who are uninsured or are insured by Medicaid are more likely to present with more advanced cancer. The objective of this study was to examine whether cancer recurrence and mortality of patients diagnosed with squamous cell carcinoma of the head and neck are associated with insurance status, after adjusting for known cancer risk factors. The main outcome measures were overall survival and relapse‐free survival.METHODS:Retrospective cohort of patients with a biopsy‐proven primary squamous cell carcinoma of the oral cavity, pharynx, or larynx diagnosed or treated at the University of Pittsburgh Medical Center between 1998 and 2007. Patients were stratified by their insurance status, including private insurance, uninsured/Medicaid, Medicare disability (Medicare under age 65), and Medicare 65 years + . Covariates included age, gender, race, smoking status, alcohol consumption, anatomic tumor site, treatment, stage at diagnosis, and occupational prestige score. Cox proportional hazards regression was used to estimate the effect of insurance status on overall survival, relapse‐free survival, tumor stage, and lymph node involvement.RESULTS:A total of 1231 patients were included in the analysis. Patients with Medicaid/uninsured (hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.07‐2.11) and Medicare disability (HR, 1.69; 95% CI, 1.16‐2.48) had significantly lower overall survival compared with patients with private insurance; the result was independent of variables known to affect outcome, such as alcohol and tobacco use. For all squamous cell carcinoma of the head and neck (SCCHN) cancer sites, Medicaid and uninsured patients were significantly more likely to present with an advanced stage tumor at diagnosis (odds ratio [OR] = 2.94; 95% CI, 1.72‐5.01) and to present with at least 1 positive lymph node (OR = 1.84; 95% CI, 1.16‐2.90) compared with patients with private insurance.CONCLUSIONS:Patients with Medicaid/uninsured and Medicare disability were at increased risk of death after a diagnosis of SCCHN when compared with patients with private insurance, after adjustment for age, gender, race, smoking, alcohol use, site, socioeconomic status, treatment, and cancer stage. Cancer 2010. © 2010 American Cancer Society.
Connexin36 is required for gap junctional coupling of most ganglion cell subtypes in the mouse retina
Authors: Pan Feng , Paul David L. , Bloomfield Stewart A. , Völgyi Béla 
Published: November 2009

AbstractConverging evidence indicates that electrical synaptic transmission via gap junctions plays a crucial role in signal processing in the retina. In particular, amacrine and ganglion cells express numerous gap junctions, resulting in extensive electrical networks in the proximal retina. Both connexin36 (Cx36) and connexin45 (Cx45) subunits are widely distributed in the inner plexiform layer (IPL) and therefore are likely contribute to gap junctions formed by a number of ganglion cell subtypes. In the present study, we used the gap junction‐permeant tracer Neurobiotin to compare the coupling pattern of different ganglion cell subtypes in wild‐type (WT) and Cx36 knockout (KO) mouse retinas. We found that homologous ganglion‐to‐ganglion cell coupling was lost for two subtypes after deletion of Cx36, whereas two other ganglion cell subtypes retained homologous coupling in the KO mouse. In contrast, deletion of Cx36 resulted in a partial or complete loss of ganglion‐to‐amacrine cell heterologous coupling in 9 of 10 ganglion cell populations studied. Overall, our results indicate that Cx36 is the predominant subunit of gap junctions in the proximal mouse retina, expressed by most ganglion cell subtypes, and thereby likely plays a major role in the concerted activity generated by electrical synapses. J. Comp. Neurol. 518:911–927, 2010. © 2009 Wiley‐Liss, Inc.