bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mutual Influence between Halogen Bonds and Cation–π Interactions: A Theoretical Study
Authors: Lu Yunxiang , Liu Yingtao , Li Haiying , Zhu Xiang , Liu Honglai , Zhu Weiliang 
Published: March 2012

AbstractThe interplay between halogen bonds and cation–π interactions is investigated by ab initio calculations at the MP2 level of theory. Different energetic effects are observed in the studied complexes in which halogen bonds and cation–π interactions coexist, which can be ascribed to the direction of charge transfer for the two interactions. These effects are analyzed in detail in terms of the structural, energetic, and charge‐transfer properties of the complexes. In addition, the quantum theory of atoms in molecules is employed to characterize the interactions and to examine their enhancement and attenuation in terms of the variations in electron density at the bond and cage critical points. Finally, experimental evidence for a combination of the two interactions is obtained from the Cambridge Structural Database.
Stroke recovery and sensory plasticity: Common mechanisms?
Authors: Moore David R. 
Published: March 2012

AbstractPresentations in this symposium are considered in the context of mechanisms of sensory plasticity, particularly in the auditory system. The auditory nervous system has two discrete end organs that are separately vulnerable to clinical and experimental injury, and brainstem processing mechanisms that are highly specialized for temporal, spectral, and spatial coding. These include giant axo‐somatic synapses and neurons with spatially segregated bipolar dendrites, each innervated exclusively from one ear. This architecture allows exquisite control of afferent‐target interactions, including known excitatory and inhibitory couplings, and consequently enhanced interpretation of data from other brain systems. For example, deafening can silence the auditory nerve, but has surprisingly little impact on normal brain function, as evidenced by the success of cochlear implants. The observed amplification from one brain region to another of degeneration following stroke or discrete brain lesions may thus be due to secondary rather than primary afferent consequences of the lesion. © 2012 Wiley Periodicals, Inc. Dev Psychobiol 54:326‐331, 2012.
Ecogeomorphic expressions of an aspect‐controlled semiarid basin: II. Topographic and vegetation controls on solar irradiance
Authors: Gutiérrez‐Jurado Hugo A. , Vivoni Enrique R. 
Published: March 2012

ABSTRACTTopography‐mediated microclimates give rise to opposing hillslope ecosystems in north facing and south facing slopes of a semiarid basin in central New Mexico. It is hypothesized that large solar irradiance differences are a driving mechanism in the observed vegetation patterns. Using a distributed solar radiation model, we explore the topography–vegetation controls on annual and seasonal irradiance in the basin. Three digital elevation models (DEMs), ranging from 1 m to 10 m resolution, and a digital surface model with tree canopies, from Light Detection and Ranging (LiDAR), are used to assess improvements in capturing irradiance differences in the opposing slopes. Remarkably reduced irradiance is found in the north facing slope throughout the year. This suggests that terrain aspect is a first‐order control on the spatial distribution of irradiance, with terrain slope leading to differences within each aspect. Tree cover and its spatial arrangement are important second‐order controls on irradiance which can overwhelm topographic effects in specific locations and times of year. For example, differences between north facing and south facing slopes are maximized in the spring equinox, rather than the winter solstice, when tree shading and reflection are accounted for. North facing trees also diminish intercanopy radiation, depending on tree cover and vegetation albedo, with important ecological implications for the conifer–grass association. Solar irradiance analysis helps identify the underlying topographic and vegetation controls on microclimate in the opposing hillslope ecosystems, suggesting a feedback mechanism that helps reinforce the differences in vegetation establishment. Copyright © 2012 John Wiley & Sons, Ltd.
Nitrile Oxide/Alkyne Cycloadditions – A Credible Platform for Synthesis of Bioinspired Molecules by Metal‐Free Molecular Clicking
Authors: Heaney Frances 
Published: March 2012

AbstractThe need for precise and flexible synthetic methodology to underpin modern research in chemical biology and materials science has fuelled a resurgence of interest in Huisgen 1,3‐dipolar cycloaddition chemistry. Of late, the in vogue chemistry for the assembly of complex biological molecules and specialist materials has been the copper‐catalysed azide alkyne cycloaddition (CuAAC) reaction. However, in certain circumstances aversion to the copper catalyst flaws this approach and alternatives have been sought. Click chemistry has developed beyond the original triazole‐forming trick and azides are no longer the only dipoles pursued as click cycloaddition partners. This article reviews some of the complications of the CuAAC reaction and evaluates the potential of nitrile oxide/alkyne cycloaddition (NOAC) as a covalent conjugation tool. With a focus on applications in nucleic acid chemistry and materials science it presents the case for a prominent position for nitrile oxides in the catalyst‐free bioconjugation toolbox.
Concise Synthesis of Norrisolide
Authors: Granger Krista , Snapper Marc L. 
Published: March 2012

AbstractThe marine natural product norrisolide has been synthesized in a convergent manner with a longest linear sequence of 14 steps. The hydrindane portion of the molecules is prepared through conjugate addition of a functionalized allyl group into cyclopentenone, followed by stereoselective trapping of the enolate generated from the resulting enol silyl ether with an allyl electrophile. Ring‐closing metathesis then establishes the 6–5 ring system. Likewise, selective preparation of the side chain features an enantioselective cyclopropanation of furan‐2‐one, followed by rearrangement and hydrogenation. Coupling of the two major fragments through a Shapiro reaction, followed by reduction and olefination then completes the carbon framework of the natural product. The final steps of the synthesis involve adjustments to the oxidation state of the side chain. New strategies to generate both the hydrindane core and the oxidized side chain has allowed for the more concise and efficient preparation of the natural product.
Emotional time travel: Emotion regulation and the overestimation of future anger and sadness
Authors: van Dijk Wilco W. , van Dillen Lotte F. , Seip Elise C. , Rotteveel Mark 
Published: March 2012

AbstractIn the present study we examined the role of four specific forms of reappraisal in people's overestimation of their future experiences of anger and sadness. Results show that forecasters predicted to experience more intense anger and sadness following social exclusion than experiencers actually felt. This impact bias was shown in both the overall intensity of these emotions and their associated response tendencies. Results also show that forecasters indicated less reappraisal of the situation than experiencers actually employ. Moreover, for experiencers, reappraisal (i.e., relativisation) of social exclusion decreased their experience of anger, whereas forecasters' predicted reappraisal was not related to their forecasted experience of anger. These findings add importantly to earlier research by indicating how a specific emotion regulatory process (i.e., reappraisal) is related to the impact bias in affective forecasting. Copyright © 2012 John Wiley & Sons, Ltd.
When curiosity kills no cat—but mediates the relation between distant future thoughts and global processing across sensory modalities
Authors: Förster Jens , Becker Daniela 
Published: March 2012

AbstractFour studies examined the effect of primed temporal distance on global versus local perception, using auditory, haptic, gustatory, and olfactory stimuli. The studies show that thinking of the more distant (versus proximal) future facilitated Gestalt perception and impaired perception of details across all four modalities: Participants thinking about the distant future listened more to the Gestalt than to the details of an artificial poem, they grasped more the overall shape than the single parts of a set of boxes, they tasted more the overall flavor than the ingredients of a müsli, and they smelled more the general aroma than the ingredients of everyday objects. The participants' self‐reported curiosity mediated our results, which is consistent with Novelty Categorization Theory. Moreover, the results are discussed within the framework of Construal Level Theory of psychological distance and GLOMOsys. Copyright © 2012 John Wiley & Sons, Ltd.
Thinking deadline: The impact of regulatory focus on deadline descriptions and deadline behavior
Authors: Woltin Karl‐Andrew , Jonas Kai J. 
Published: March 2012

AbstractIn everyday life, people are constantly faced with deadlines. The current research investigated whether a self‐regulatory orientation in terms of promotion and prevention focus impacts on what individuals center on when considering deadlines. Specifically, we assumed promotion focus to enhance thinking about deadline descriptions and prevention focus to enhance thinking about deadline‐related behavior, both in terms of their self‐regulatory concerns (i.e., advancement versus security). Studies 1a and 1b, across a multitude of deadlines, provide evidence for this: Chronic promotion focus was related to growth‐oriented deadline descriptions whereas chronic prevention focus was related to safety‐oriented deadline behavior. Additionally, Study 1c shows that effects stem from experiences with past deadlines rather than deliberations of future deadlines. Finally, Study 2, manipulating regulatory focus and having participants spontaneously generate texts in relation to one specific deadline, replicated the effect for descriptions versus behavior. In sum, our results show that individuals' self‐regulation impacts on deadline conceptualizations. Copyright © 2012 John Wiley & Sons, Ltd.
Pursuing perfection or pursuing protection? Self‐evaluation motives moderate the behavioral consequences of counterfactual thoughts
Authors: Tyser Maurissa P. , McCrea Sean M. , Knüpfer Kristin 
Published: March 2012

AbstractCounterfactual thoughts identifying how a past performance could have been better (e.g., “If only I had studied for the exam, I would have gotten an A!”) have been shown to increase effort and performance on future tasks. The present work examines whether current self‐evaluation motives moderate this link between past and future behavior. In two studies, we demonstrate that the preparatory benefits of counterfactual thoughts are limited to situations in which individuals pursue a self‐improvement motive. When individuals are instead motivated by self‐protection concerns, counterfactuals can be used to excuse poor performance, undermining any desire to improve in the future. The behavioral consequences of counterfactual thoughts are therefore dependent upon active self‐evaluation motives. Copyright © 2012 John Wiley & Sons, Ltd.
Mental time travel: A conceptual overview of social psychological perspectives on a fundamental human capacity
Authors: Epstude Kai , Peetz Johanna 
Published: March 2012

AbstractHumans have the unique capacity to mentally travel through time, that is, to reflect on the past, anticipate the future, and construct alternate realities in their minds. The ability to mentally travel through time affects a variety of social psychological topics. Representations of events can differ considerably, depending on the event's temporal location and distance from the present. Current emotions may be influenced by thoughts of future and past times (e.g., nostalgia, hope). Judgments about future events and actions are an important aspect of everyday functioning (e.g., predictions). Indeed, hypothetical thought about counterfactual events that might never come to pass may change the perception and evaluation of present reality. Despite this varied and extensive influence of time on affect, judgment, perception, and behavior, these diverse topics have not been brought together under one common roof. In this overview article and in the special issue on Mental Time Travel, we aim to identify key themes of mental time travel research, point to communalities and differences, and help to integrate various aspects of mental time travel research. Future directions regarding open questions, need for theoretical integration, and further empirical research are discussed. Copyright © 2012 John Wiley & Sons, Ltd.
Talking loudly but lazing at work—Behavioral effects of stereotypes are context dependent
Authors: Müller Florian , Rothermund Klaus 
Published: March 2012

AbstractRecent research suggests that stereotype activation is context dependent. In the current research, we tested whether this context‐dependence also generalizes to behavioral effects of stereotypes. Extending previous findings, we could show that activation of the category “Italians” in a work context (but not in an interaction context) resulted in slow behavior (Experiment 1), whereas it increased the loudness of speech in an interaction context (but not in a work context; Experiment 2). Our results further strengthen the notion of context‐specific mental representations of stereotypes. Stereotypic attributes become activated and exert their influence on behavior in close correspondence with the current situation. Copyright © 2012 John Wiley & Sons, Ltd.
Recovery from Disordered Eating: Sufferers' and Clinicians' Perspectives
Authors: Emanuelli Francesca , Waller Glenn , Jones‐Chester Matthew , Ostuzzi Roberto 
Published: March 2012

AbstractObjectiveDisagreement exists on how to define recovery from eating disorders. Definitions typically include a combination of physical, cognitive, emotional, psychological and social factors. However, none provides multidimensional recovery models, addressing and comparing sufferers'1 and clinicians' viewpoints. This study investigates those recovery perspectives.MethodTwo‐hundred and thirty‐eight participants (individuals with eating difficulties and clinicians working in the field) completed a checklist, rating the importance of somatic, psychological, emotional, social, eating‐related and body experience‐related recovery criteria.ResultsRecovery criteria fell into meaningful factors (psychological–emotional–social, weight‐controlling behaviours, non‐life‐threatening and life‐threatening features and evaluation of one's own appearance). Sufferers and clinicians agreed on the ranking of importance of these factors. However, sufferers considered ‘psychological–emotional–social’ and ‘evaluation of one's own appearance’ criteria as more important to recovery than clinicians.DiscussionFindings are discussed in relation to existing research, together with study limitations and future research. Clinical implications are outlined, focusing on the facilitation of recovery. Copyright © 2012 John Wiley & Sons, Ltd and Eating Disorders Association.
In vitro exposure to fullerene C60 influences redox state and lipid peroxidation in brain and gills from Cyprinus carpio (Cyprinidae)
Authors: Ferreira Josencler L.R. , Barros Daniela M. , Geracitano Laura A. , Fillmann Gilberto , Fossa Carlos Eduardo , de Almeida Eduardo A. , de Castro Prado Mariana , Neves Bernardo Ruegger Almeida , Pinheiro Maurício Veloso Brant , Monserrat José M. 
Published: March 2012

Abstract
Studies concerning the impact of nanomaterials, especially fullerene (C60), in fresh water environments and their effects on the physiology of aquatic organisms are still scarce and conflicting. We aimed to assess in vitro effects of fullerene in brain and gill homogenates of carp Cyprinus carpio, evaluating redox parameters. A fullerene suspension was prepared by continued stirring under fluorescent light during two months. The suspension concentration was measured by total carbon content and ultraviolet–visible spectroscopy nephelometry. Characterization of C60 aggregates was performed with an enhanced dark-field microscopy system and transmission electronic microscopy. Organ homogenates were exposed during 1, 2, and 4 h under fluorescent light. Redox parameters evaluated were reduced glutathione and oxidized glutathione, cysteine and cystine, total antioxidant capacity; activity of the antioxidant enzymes glutathione S-transferase and glutathione reductase (GR), and lipid peroxidation (TBARS assay). Fullerene induced a significant increase (p &lt; 0.05) in lipid peroxidation after 2 h in both organs and reduced GR activity after 1 h (gills) and 4 h (brain) and antioxidant capacity after 4 h (brain). Levels of oxidized glutathione increased in the brain at 1 h and decreased at 2 h as well. Given these results, it can be concluded that C60 can induce redox disruption via thiol/disulfide pathway, leading to oxidative damage (higher TBARS values) and loss of antioxidant competence. Environ. Toxicol. Chem. 2012; 31: 961–967. © 2012 SETAC
Oxidative damage and antioxidant response of Allium cepa meristematic and elongation cells exposed to metronidazole
Authors: Andrioli Nancy , Sabatini Sebastián E. , Mudry Marta D. , Ríos de Molina María del Carmen 
Published: March 2012

Abstract
The toxicity of metronidazole (MTZ) in meristematic and elongation zones of Allium cepa roots was analyzed for 30 h of exposition. Toxic effects were evaluated by lipid peroxidation (content of thiobarbituric-reactive substances [TBARS]), reduced glutathione (GSH) levels, ascorbate acid and dehydroascorbate acid content, and enzymatic activities of superoxide dismutase and catalase. The root zones showed differentiated susceptibility to MTZ. In the elongation zone, MTZ induced an increase of TBARS content and a significant rise in GSH levels, whereas in the meristematic zone, lipid peroxidation was not observed and all antioxidant defense parameters analyzed were significantly increased. These results indicate that MTZ exposure induced oxidative stress in A. cepa roots, and that the antioxidant defenses in the meristematic zone are more efficient compared with the elongation zone, which is probably related to higher oxidative metabolism of meristematic tissue. Environ. Toxicol. Chem. 2012; 31: 968–972. © 2012 SETAC
Temporal relationships between depressive symptoms and white matter hyperintensities in older men and women
Authors: Dotson Vonetta M. , Zonderman Alan B. , Kraut Michael A. , Resnick Susan M. 
Published: March 2012

ObjectiveAssociations between vascular disease and depression in late life, including increased white matter hyperintensities (WMHs), have been reported. Whether depression is an etiology or a consequence of vascular disease is still unknown. We investigated the temporal relationship between depressive symptoms and WMHs in older men and women.MethodsWe utilized data from 90 dementia‐free older adults (39 women, 51 men), 57 years of age and older at baseline, from the neuroimaging substudy of the Baltimore Longitudinal Study of Aging. Participants were followed for up to 8 years. Ratings of white matter disease burden were available for the first, last, and at least one interim visit, and participants completed the Center for Epidemiologic Studies Depression Scale (CES‐D) annually. Statistical models, performed separately in men and women, examined whether depressive symptoms predicted subsequent WMH ratings or WMHs predicted subsequent depressive symptoms.ResultsThe total CES‐D score was not associated with WMHs in men or women. In men, the CES‐D depressed mood subscale predicted accelerating longitudinal increases in WMHs at older ages, but WMHs did not predict subsequent depressive symptoms. In women, there were no significant associations between the CES‐D depressed mood subscale and WMHs.ConclusionsWhite matter disease may be a consequence of depressed mood in men but not in women. Intervention strategies for depression may slow the progression of white matter disease in older men. These results add to previous findings documenting sex differences in the correlates of depressive disorders in late life. Copyright © 2012 John Wiley & Sons, Ltd.
A randomized control trial of integrated care for families managing infant colic
Authors: Salisbury Amy L. , High Pamela , Twomey Jean E. , Dickstein Susan , Chapman Heather , Liu Jing , Lester Barry 
Published: March 2012

AbstractThis article presents a randomized clinical trial examining the effectiveness of a unique model of integrated care for the treatment of infant colic. Families seeking help for infant colic were randomized to either the family‐centered treatment (TX; n = 31) or standard pediatric care (SC; n = 31). All parents completed 3 days of Infant Behavior Diaries (Barr et al., 1998) and the Colic Symptom Checklist (Lester, 1997), Beck Depression Inventory (Beck & Steer, 1984), and Parenting Stress Index 3rd ed.‐SF (Abidin, 1995). TX families were seen three times by a pediatrician and a mental health clinician within 1, 2, and 6 weeks of baseline data. TX families received individualized treatment plans addressing problem areas of sleep, feeding, routine, and family mental health. SC families were seen only by their own healthcare provider. All families were visited at home by a research assistant to retrieve data at 2, 6, and 10 weeks after baseline. Family‐based treatment accelerated the rate of reduction of infant crying faster than did standard pediatric care. Infants in the TX group had more hours of sleep at 2 weeks posttreatment and spent less time feeding at 2, 6, and 10 weeks posttreatment than did SC infants. Results indicate that individualized family‐based treatment reduces infant colic more rapidly than does standard pediatric care.
Development of regulation disorders into specific psychopathology
Authors: Bron Tannetje I. , van Rijen Elisabeth H.M. , van Abeelen Alexandrina M. , Lambregtse‐van den Berg Mijke P. 
Published: March 2012

AbstractUnderlying deficits in self‐regulation and sensory processing are seen in children with regulation disorders (RD) and might lead to emotional and behavioral problems as the child develops. However, little is known about the specific developmental course of RD. This follow‐up study was conducted to investigate the development of a clinical sample of RD children, diagnosed by means of the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, Revised (DC:0–3R; ZERO TO THREE, 1994), toward specific psychopathology 4 to 10 years later based on parent‐ and teacher‐reports on the Child Behavior Checklist (T.M. Achenbach & L.A. Rescorla, 2007). Parental reports showed that 39 to 69% of children with RD had internalizing, externalizing, and total problems above borderline cutoffs, as compared to norm group data (16%). In addition, higher rates of affective, anxiety, attention deficit/hyperactivity, oppositional defiant, and conduct problems were reported. Analyses between RD subtypes showed significant differences on future attention problems and rule‐breaking behavior, wherein less favorable results were found for the Hypersensitive subtype Type A (fearful/cautious) in comparison to the sensory stimulation‐seeking/impulsive subtype. The current results indicate persistence of emotional and behavioral problems into middle childhood and adolescence in children with preschool RD diagnoses. More attention should be paid to differentiation of psychopathology in these children since developmental outcomes may differ between RD subtypes.