bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trading Gamification and Investor Behavior
Authors: Chapkovski Philipp , Khapko Mariana , Zoican Marius 
Published: June 2024

We study the effect of gamification on retail traders’ behavior using a randomized online experiment. Participants with lower financial literacy prefer platforms with hedonic gamification elements, such as confetti and achievement badges. On average, hedonic gamification increases trading volume by 5.17%. However, the difference in trading activity between gamified and nongamified platforms is driven primarily by self-selection (70%) rather than gamification (30%). Participants who prefer hedonic gamification exhibit noisy trading strategies, whereas those favoring nongamified platforms display stronger contrarian behavior. Further, price trend notifications enhance learning for investors with accurate beliefs, but they reinforce trading mistakes for those with incorrect beliefs. This paper has been This paper was accepted by Jean-Edouard Colliard for the special issue on the human-algorithm connection. Funding: P. Chapkovski acknowledges funding from the Deutsche Forschungsgemeinschaft [Germany’s Excellence Strategy—EXC 2126/1-390838866]. M. Khapko and M. Zoican acknowledge the Social Sciences and Humanities Research Council of Canada [Insight Development Grant 430-2018-00125] and the Canadian Securities Institute Research Foundation [research grant]. M. Zoican acknowledges financial support from the Quantitative Management Research Initiative (QMI) under the aegis of the Fondation du Risque, a joint initiative by Université Paris-Dauphine, l’École Nationale de la Statistique et de l’Administration ParisTech, and LFIS, France. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2022.02650 .
Effect of dapagliflozin on uric acid in patients with chronic heart failure and hyperuricemia
Authors: Lin Meng-Jiao , Zou Shu-Bin , Zhu Bai-Xiang 
Published: June 2024

BACKGROUND
Patients with chronic heart failure (CHF) frequently develop hyperuricemia, an elevated serum uric acid level, associated with adverse outcomes. Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, demonstrates reduction in cardiovascular mortality and hospitalization in patients with CHF and ejection fraction (HFrEF), irrespective of diabetes. However, dapagliflozin’s effect on the uric acid levels in patients with CHF and hyperuricemia remain unclear.
AIM
To investigate the effects of dapagliflozin on uric acid levels in CHF patients with hyperuricemia.
METHODS
We conducted a randomized, double-blind, placebo-controlled trial in 200 patients with CHF and hyperuricemia, with HFrEF and serum uric acid levels ≥ 7 mg/dL (≥ 416 μmol/L). The participants were randomly assigned to receive a daily dose of 10 mg dapagliflozin or placebo for 24 months. The primary endpoint was the change in serum uric acid level from baseline to 24 months. Secondary endpoints included changes in left ventricular ejection fraction (LVEF), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and quality of life (QoL) scores, as well as the incidence of cardiovascular death and hospitalization for heart failure.
RESULTS
At 24 months, dapagliflozin significantly reduced serum uric acid levels by 1.2 mg/dL (71 μmol/L) compared with placebo (95%CI: -1.5 to -0.9; P < 0.001). Dapagliflozin also significantly improved LVEF by 3.5% (95%CI: 2.1-4.9; P < 0.001), NT-proBNP by 25% (95%CI: 18-32; P < 0.001), and QoL scores by 10 points (95%CI: 7-13; P < 0.001) and reduced the risk of cardiovascular death and hospitalization for heart failure by 35% (95%CI: 15–50; P = 0.002) compared with the placebo. Adverse events were similar between the two groups, except for a higher rate of genital infections in the dapagliflozin group (10% vs 2%, P = 0.01).
CONCLUSION
Dapagliflozin significantly lowered serum uric acid levels and improved the clinical outcomes in patients with CHF and hyperuricemia. Therefore, dapagliflozin may be a useful therapeutic option for this high-risk population.
A comparative study of acupuncture combined with rehabilitation gymnastics on postoperative anal function of lower rectal cancer
Authors: Liu Zhan-Lun , He Yi-Wei , Liu Yan-Feng , Wang Ni , Li Wei , Shen Li-Zhong 
Published: June 2024

BACKGROUND
From the anal function, inflammatory response and other indicators, acupuncture combined with rehabilitation gymnastics was applied to patients with cancer undergoing low resection, aiming to improve the prognosis of patients.
AIM
To explore the effects of acupuncture combined with rehabilitation gymnastics on anal function after lower rectal cancer surgery.
METHODS
From January 2020 to December 2022, 128 patients who underwent rectal cancer surgery in the Department of Oncology of Hebei Provincial Hospital of Traditional Chinese Medicine Hospital were selected and divided into two groups using the random number table method, with 64 patients in each group. Patients in the control group were not treated with acupuncture or rehabilitation gymnastics and served as blank controls. Patients in the study group were treated with acupuncture and rehabilitation gymnastics from the 7th postoperative day. The anal incontinence scores, changes in serum interleukin-4, interleukin-6, and interleukin-10 Levels, and serum motilin, 5-hydroxytryptamine, and vasoactive intestinal peptide levels were compared.
RESULTS
There were no significant differences in serum interleukin-4, interleukin-6, and interleukin-10 Levels between the groups before treatment (P > 0.05). After treatment, these levels were better than those of the control group (P < 0.05). There was no significant difference in the anal incontinence scores between the groups before and 7 d after surgery (P > 0.05). Anal incontinence scores in the study group were lower than those in the control group at 14 d, 21 d, and 28 d postoperatively (P < 0.05). There were no significant differences in serum motilin, 5-hydroxytryptamine, or vasoactive intestinal peptide levels between the groups before treatment (P > 0.05). After treatment, these levels were higher in the study group than in the control group, and vasoactive intestinal peptide level was lower in the study group than in the control group (P < 0.05).
CONCLUSION
Acupuncture combined with rehabilitation gymnastics can promote the recovery of anal function and reduce the inflammatory response in patients with lower rectal cancer after surgery.
Human herpesvirus 7 meningitis in an adolescent with normal immune function: A case report
Authors: Zhen Yuan-Yuan , Yang Jing , Liao Pei-Yuan 
Published: June 2024

BACKGROUND
Human herpesvirus type 7 (HHV-7) is a less common herpes virus that usually causes mild, self-limiting illnesses. However, in recent years, there have been increasing reports of HHV-7 causing serious central nervous system infections, especially meningitis. The pathogenesis and clinical features of HHV-7 meningitis, particularly in adolescents with normal immune function, remain incompletely studied. Therefore, the purpose of this report is to share a case of HHV-7 meningitis in an immunocompetent adolescent with a view to deepening our understanding of the disease.
CASE SUMMARY
A 12-year-old female was admitted with fever, headache, and vomiting. 4 d before admission, the patient developed a fever without obvious induction, with a temperature up to 39.5 °C, no convulsions, accompanied by chills, headaches, fatigue, and no muscle aches. The patient was treated with fever reduction, which could be reduced to 38 °C; repeated high fever, accompanied by vomiting 7-8 times; and no abdominal pain or diarrhea. The patient was diagnosed with "acute suppurative tonsillitis" in a local hospital, and the blood routine was generally normal. The patient was given symptomatic support treatment such as "ceftriaxone sodium" and antiemetic rehydration for 2 d, and his condition did not improve. The patient's physical examination showed pharyngeal congestion, bilateral tonsil grade I hypertrophy, regression of purulent secretions, and cervical resistance. Ocular B-ultrasound: Opacity of the vitreous body and edema of the optic disc in both eyes. Optical coherence tomography examination showed that the macular fovea was generally normal in both eyes, with edema of the optic disc. DNA virus monitoring results: HHV-7. We gave ganciclovir antiviral therapy, dexamethasone anti-inflammatory treatment, mannitol to reduce cranial pressure, omeprazole to protect gastrointestinal mucosa, and calcium and potassium supplementation.
CONCLUSION
This study reports a case of HHV-7 meningitis in an adolescent with normal immune function. Through comprehensive analysis of the clinical manifestations, laboratory tests, and treatment methods of the patient, it is found that early identification and antiviral treatment are essential for the outcome of the disease. This case suggests that despite normal immune function, adolescents may still suffer from herpes virus type 7 meningitis, so clinicians should be vigilant and take effective treatment measures in time.
LONG-TERM OUTCOMES OF A RANDOMIZED CONTROLLED TRIAL COMPARING FIBULAR NAIL WITH OPEN REDUCTION AND INTERNAL FIXATION IN PATIENTS WITH UNSTABLE ANKLE FRACTURES
Authors: Heinz N. , Bugler K. , Clement N. , Low X. , Duckworth A. , White T. 
Published: June 2024

BackgroundStudies have compared open reduction internal fixation (ORIF) with fibular nail fixation (FNF) and shown reduced wound complications with minimal difference to PROMS in the short term. Our aim is to compare long-term outcomes for unstable ankle fractures at 10 year follow up.MethodsPatients from a previously conducted RCT were contacted at a minimum of 10 years post intervention at a single study centre. Case notes were reviewed, and patient reported outcome measures acquired at 10 years.ResultsNinety-nine patients were included (48 FNF and 51 ORIF). After 10 years 75% (33/44) of patients in the FNF group required no further follow up versus 81% (39/48) in the ORIF group. Radiographically at 2 years post-injury, there was no statistically significant difference between groups for development of osteoarthritis (p=0.851). There was one tibio-talar fusion in each group secondary to osteoarthritis, but no statistically significant difference in overall re-operation rate (p=0.518). Fifty-one percent (n=50) of patients have so far returned patient reported outcome measures at a minimum of 10 years (Fibular nail n=23, plate fixation n=27). No significant difference was found between groups for the mean scores of Olerud and Molander Ankle Score (FNF 84.78 vs ORIF 84.07; p=0.883), the Manchester-Oxford Foot Questionnaire (MOXFQ) (FNF 89.54 vs ORIF 96.47; p=0.112), Euroqol-5D Index (FNF 0.88 vs ORIF 0.87; p=0.701) and Euroqol-5D Visual Analogue Score (FNF 77.30 vs ORIF 77.52; p=0.859).ConclusionThe current study illustrates that both methods of treatment result in a satisfactory long-term outcome with no difference in late complications or PROM scores at up to 10 years in patients under 65 years old, although the study is currently under powered.
THE INCIDENCE OF VTE IN FOOT AND ANKLE SURGERY IN THE UK: UK FOOT AND ANKLE THROMBO-EMBOLISM AUDIT (UK-FATE)
Authors: Mason L. , Mangwani J. , Malhotra K. , Houchen-Wolloff L. 
Published: June 2024

IntroductionVTE is a possible complication of foot and ankle surgery, however there is an absence of agreement on contributing risk factors in the development of VTE. The primary outcome of this study was to analyse the 90-day incidence of symptomatic VTE following foot and ankle surgery and to determine which factors may increase the risk of VTE.MethodsThis was a national, multi-centre prospective audit spanning a collection duration of 9 months (2022/2023). Primary outcomes included incidence of symptomatic VTE and VTE related mortality up to 90 days following foot and ankle surgery and Achilles tendon rupture, and analysis of risk factors.ResultsIn total 11,363 patients were available for analysis. 5,090 patients (44.79%) were elective procedures, 4,791 patients (42.16%) were trauma procedures (excluding Achilles ruptures), 398 patients (3.50%) were acute diabetic procedures, 277 patients (2.44%) were Achilles ruptures undergoing surgery and 807 patients (7.10%) were Achilles ruptures treated non-operatively. There were 99 cases of VTE within 90 days of admission across the whole group (Total incidence = 0.87%), with 3 cases of VTE related mortality (0.03%). On univariate analysis, increased age and ASA grade showedhigher odds of 90-day VTE, as did previous cancer, stroke, history of VTE, and type of foot and ankle procedure / injury (p<0.05). However, on multivariate analysis, the only independent predictors for 90-day VTE were found to be the type of foot and ankle procedure (Achilles tendon rupture = Odd's Ratio 11.62, operative to 14.41, non-operative) and ASA grade (grade III/IV = Odd's Ratio 3.64).ConclusionThe incidence of 90-day post procedure VTE in foot and ankle surgery in this national audit was low. Significant, independent risk factors associated with the development of 90-day symptomatic VTE were Achilles tendon rupture management and high ASA grade.
ARTHROSCOPIC SUBTALAR ARTHRODESIS: A LARGE CASE SERIES OF 135 PATIENTS
Authors: Shah K. , Battle J. , Hepple S. , Harries B. , Winson I.G. , Robinson P.W. 
Published: June 2024

BackgroundOpen subtalar arthrodesis has been associated with a moderate rate of non-union, as high 16.3%, and high rates of infection and nerve injury. Performing this operation arthroscopically serves to limit the disruption to the soft tissue envelope, improve union rates and reduce infection. Our study describes our outcomes and experience of this operation.MethodRetrospective review of all patients who underwent an arthroscopic subtalar arthrodesis between 2023 and 2008. We excluded patients undergoing concurrent adjacent joint arthrodesis. The primary aim was to report on rates of union. Secondary outcomes included reporting on conversion to open procedure, duration of surgery, infection, and iatrogenic injury to surrounding structures.Results135 patients were included in the final analysis. 129 patients (95.5%) achieved union. The median time to fusion was 98 days. All cases were performed through sinus tarsi portals. 38 cases were performed with an additional posterolateral portal. Most cases (107/77%) were performed with 2 screws. 3 cases (2.2%) were converted to open procedures. The median tourniquet time was 86 minutes but available in only 88 (65%) cases. There were 4 (2.9%) superficial infections and no deep infections. 1 patient sustained an injury to FHL and there were no reported nerve injuries.ConclusionsAt present this is the largest series of arthroscopic subtalar arthrodeses. We demonstrate that this operation can achieve high rates of union with low rates of infection with an equally low likelihood of needing to convert to an open procedure with modest operative times. In our experience the addition of a posterolateral portal does not appear to increase the incidence of nerve injury and aids in the visualisation of all 3 facets.
VILÉM FLUSSER E GUIMARÃES ROSA
Authors: De Castro Gustavo , Andrade Bornhausen Diogo 
Published: June 2024

Neste artigo realizamos três aproximações entre Vilém Flusser e Guimarães Rosa: uma biográfica, outra filosófica e uma terceira estética. A partir de estudos anteriores, entrevistas, pesquisas no Arquivo Flusser e no Fundo João Guimarães Rosa (FJGR/IEB/USP) propomos uma interpretação da relação pessoal entre ambos e uma crítica ponderada dos interesses intelectuais e estéticos de Vilém Flusser sobre Guimarães Rosa. Nossas conclusões apontam para a importância de novas pesquisas sobre as trocas e intercâmbios entre os dois autores. A relação deles foi profícua sobretudo para Flusser e ainda hoje temos dificuldade de mapear o grande número de pontos de contatos.
Palavras-Chave: Vilém Flusser. Guimarães Rosa. Diálogos.
O IMAGINÁRIO COMO POTÊNCIA EM VILÉM FLUSSER
Authors: NESPOLI EDUARDO 
Published: June 2024

RESUMO: O propósito do artigo é investigar a concepção de imaginário na filosofia de Vilém Flusser e sua relação com a arte. Para tanto, examinamos como o filósofo trabalha outros conceitos relacionados, tais como abstrato e concreto, subjetividade e objetividade, arte e jogo, considerando a relação estabelecida com diferentes suportes e meios. A argumento central do texto explora a ideia de que Flusser concebe o imaginário como potência que codifica e transforma o mundo. Os diversos suportes e tecnologias destacados por Flusser em sua obra operam com o corpo, refletindo diferentes níveis de consciências e modos de imaginar. Aprofundando tal abordagem e considerando o deslocamento de materiais e a objetificação do mundo como o gesto primordial, avançamos em direção ao conceito de pós-história com objetivo de compreender as relações específicas entre o imaginário e os aparelhos neste contexto. Por fim, assinalamos como arte, jogo e tecno-imaginação emergem na filosofia de Flusser enquanto princípios de um tipo de experiência imaginativa que envolve a transformação de sentidos e experiências.
PALAVRAS-CHAVE: Imaginário; Potência; Arte; Jogo.

ABSTRACT: The purpose of the article is to investigate the conception of imaginary in the philosophy of Vilém Flusser. To this end, we examine how the philosopher formulates other related concepts, such as abstract and concrete, subjectivity and objectivity, art and game, considering the relationship with different media. The central argument of the text explore the idea that Flusser conceives the imaginary as a potency that encodes and transforms the world. The several media and technologies highlighted by Flusser in his work operate with body, reflecting different levels of consciousness and modes of imagining. Working with this approach and considering the displacement of materials and the objectification of the world as the primordial gesture, we move towards the concept of post-history with the aim of understanding the specific relationships between imaginary and apparatuses in this context. Finally, we point out how art, game and techno-imagination emerge as principles of a type of imaginative experience that involves the transformation of meanings and experiences.
KEYWORDS: Imaginary; Potency; Art; Game.
PRÁTICAS PEDAGÓGICAS MUSICAIS DOS PROFESSORES E A AUTORREGULAÇÃO DA APRENDIZAGEM
Authors: Hélio Silva de Souza Júnior  , Monica Cajazeira Santana Vasconcelos  
Published: June 2024

Partimos da premissa que o ensino de música deve ser garantido como conteúdo escolar a partir da alteração da Lei de Diretrizes e Bases de 1996 pela lei 11.769 de agosto de 2008 e, posteriormente pela Lei 13.278/2016, que inclui as artes visuais, a dança, amúsica e o teatro nos currículos dos diversos níveis da educação básica.
Imaging sensor band comparison for situational awareness in wildfires
Authors: Leslie Patrick , Follansbee Joshua , Jordan Shane , Watson Thomas , Wiley Lindsey , Jacobs Eddie , Driggers Ronald 
Published: June 2024

In recent decades, wildfires have become increasingly widespread and hazardous. Dryer, hotter weather combined with more frequent heat waves leave forest areas susceptible to sudden, intense, and fast-growing forest fires. To protect private property and mitigate the damage, Hotshot firefighters are deployed into these dangerous situations. Extensive satellite and aerial platforms possess optical techniques for monitoring wildfire risks and boundary tracking. Small unmanned aerial system (sUAS)-based EO/IR systems provide a solution for real-time, high resolution, targeted response to acquire information critical to the safety and efficacy of wildfire mitigation. Real-time imagery from a sUAS of the position of Hotshots and the progression of the fire boundary would be easily obtained and offer a method of ensuring safe deployment. An ideal sensor system for situational awareness in this environment would be able to image the ambient terrain and firefighters with good contrast while also detecting fire signatures and imaging through the smoke. Longer wavelength infrared bands have demonstrated imaging through the smoke of forest fires. However, near the wildfire where the Hotshots work, they also receive strong radiometric signals from the temperature of the smoke. The emitted signal of the smoke can obscure the line of sight similarly to the scattering effect of wildfire smoke in the visible spectrum. The reflective and emissive components of a wildfire scene are studied and compared in the visible (VIS, 0.4–0.7 µm), shortwave infrared (SWIR, 1.0–1.7 µm), extended SWIR (eSWIR, 2.0–2.5 µm), and longwave infrared (LWIR, 8–14 µm). Both a radiometric model and calibrated field measurements find a band that has the highest, to our knowledge, probability for a continuous line of sight for terrain, firefighters, and fire signatures in a wildfire scene.
Urinary α 1-microglobulin and β 2-microglobulin as markers of early kidney injury in HIV-positive male patients on tenofovir-based antiretroviral therapy
Authors: Yu Xiao Li , Sun Wen , Liu Li , Hong Ke , Song Hui 
Published: June 2024

Background
A retrospective study was conducted to explore the urinary expression of α 1-microglobulin (α1MG) and β2-microglobulin (β2MG) in patients with human immunodeficiency virus (HIV) infection, aiming to evaluate their predictive capability for renal injury.

Method
One hundred and five male HIV-infected patients treated with Tenofovir (TDF) regimen (TDF+3TC or the third drug TDF/FTC+) were selected between March 1, 2021, and March 1, 2022, in Wuhan Jinyintan Hospital. Three months after TDF treatment, the renal function injury was evaluated with the standard creatinine clearance rate. The urinary levels of α1MG and β2MG were compared between the initiation of TDF treatment and three months thereafter. Spearman correlation was utilized to analyze the correlation between the urinary expression of α1MG and β2MG and renal injury in HIV patients. The logistic regression was used to analyze the predictive value of urinary α1MG and β 2-microglobulin expression in renal injury.

Results
Up to the first follow-up, 29 (27.6%) cases of the 105 male HIV patients had varying degrees of renal function injury, including 14 (13.3%) mild injury, 9 (8.6%) moderate injury, and 6 (5.7%) severe injury cases. Patients with severe renal injury had the highest levels of urinary α1MG and β2MG expression while those with mild injury demonstrated higher levels compared to the non-injury group (P < 0.05). Spearman correlation analysis indicated that urinary α1MG and β2MG were positively correlated with renal impairment in HIV patients (Rho = -0.568, and -0.732; P < 0.001). The ROC curve analysis demonstrated that the area under the curve (AUC) for urine α1MG and β2MG in predicting kidney damage among HIV patients were 0.928, 0.916, and 0.889, respectively. The sensitivity values were 96.55%, 82.76%, and 89.66% while the specificity values were 84.07%, 94.51%, and 89.29% for urine α1MG and β2MG, respectively.

Conclusion
The expression level of urinary α1MG and β2MG in HIV patients was significantly higher compared to normal people. Detection of these two indexes can enable early determination of renal injury and its severity in HIV patients.