bluuebunny/crossref_metadata_2025_split huggingface dataset:
Explanation based on thermodynamic parameters regarding effect of sensing film thickness and amount of graphene oxide on sensor performance in aniline, N-phenylglycine and graphene oxide based electrochemical heavy metal ion sensor
Authors: Dutta Kusumita , Panda Siddhartha 
Published: June 2024

Background: To construct a heavy metal ion sensor, selectivity and sensitivity are the key important parameters to be taken care of. In our earlier work, film thickness and amount of graphene oxide (GO) content in a novel composite ANGO, synthesized from aniline, N-phenylglycine and GO was varied and sensing parameters including sensitivity, limit of detection (LOD), thermodynamic parameter which includes -∆Gad and charge transport parameter including barrier width (BW), d, of charge transfer based on Simmon’s model were evaluated and compared and an LOD of 800 ppt for Cd2+ was achieved using square wave voltammetry (SWV) withstanding interference from several ions.
Methods: In this work, thermodynamic factors such as -∆Gad, ∆H, reorganization energy, partition coefficient and solvated ionic radius were used to explain the sensor performance with respect to film thickness and amount of GO. All the parameters were analyzed for different film thicknesses and amount of GO and a correlation was achieved. Finally, effect of electrochemical surface area of different polyaniline-based material on thermodynamic properties of detection process of Cd2+ was studied.
Results: The variation of the thermodynamic properties for Cd2+ sensing with respect to film thickness and amount of GO were examined. Similarly, variation of thermodynamic properties for polyaniline based different sensing materials were examined. Correlation coefficients were developed from the thermodynamic parameters and the d values to explain the underlying mechanism behind improved sensor performance.
Conclusions: This study can provide information on the thermodynamic properties which can be predicted from BW technique. The correlation coefficients would help in designing polyaniline based novel sensing film material with the need of lesser number of experiments.
Knowledge, Attitude and Perception of Hypertension among Residents of Akpor Community in Rivers State: A Descriptive Cross-Sectional Study
Authors: Oti Ifeanyi Kalu , Ayerite Annette  Benjamin , Apata Feminiyi , Omisore Olabayo Kehinde , Ibienebakabobo Promise Vivian , Yusuf Rabiu 
Published: June 2024

Background: Hypertension, also known as high blood pressure, is a serious condition of public health concern. It is the leading modifiable risk factor for cardiovascular disease and premature death worldwide, and can increase the risk of heart, brain, kidney and other diseases.
Aim: This study aimed at determining the knowledge, attitude, and perception of hypertension among residents of Akpor kingdom, a semi-urban community in Rivers State.
Methods: The study adopted a descriptive cross-sectional study design in which 284 apparently healthy community-based adult male and female individuals were purposively selected in four semi-urban communities of Akpor kingdom in Obio-Akpor Local Government Area of Rivers State. A structured questionnaire consisting of socio-demographic characteristics and research questions on knowledge, attitude and perception of hypertension was self-administered to the participants after obtaining their informed consents. All other ethical procedures were followed in line with the Declaration of Helsinki. Data was analyzed using SPSS version 25. Descriptive statistics was used to present the data in frequency tables.
Results: Majority of the respondents were males 154 (54.2%), married 195 (68.7%), and between the ages of 40 and 50 (41.5%). Majority 164 (57.8%) had good knowledge of hypertension while 18 (6.3%) had no knowledge of hypertension at all. The prevalence of hypertension was 62 (21.8%), while 102 (35.9%) were not aware whether or not they were hypertensive. Majority of the hypertensive respondents 48 (16.9%) knew their status through medical diagnosis in hospitals/clinics while 14 (4.9%) knew theirs through other means. Majority of the hypertensive respondents 34 (54.8%) had a positive attitude in seeking healthcare while 28 (45.2%) had a negative attitude. Regarding lifestyle modification, 16 (25.8%) had a negative attitude/perception of hypertension out of which 9 (14.5%) never engaged in any form of lifestyle modification, while 7 (11.3%) managed their condition through prayers and other religious practices.
Conclusion: A substantial percentage of most adult community dwellers still have poor knowledge of hypertension and negative attitude towards seeking healthcare despite the seemingly increase in public health campaigns in our communities. There is need for all stakeholders to join hands and intensify campaigns that would educate the populace on facts about hypertension, its prevention and management
Socio-economic Factors Involved for the Risk in Cotton Cultivation in Odisha
Authors: Padhy Chitrasena , Reddy M. Devender , Raj Rabindra Kumar 
Published: June 2024

Background: The cotton cultivation involves risks due to climatic variation, the most important being aberrant rainfall. Further, the farmers fetch poor returns to their produce due to quality maintenance of lint during harvesting and storage. The farmers face problem in marketing as the cotton trade is mostly done by local traders. Hence, the current study was carried to identify risks involved in cotton cultivation due to climatic variation, harvesting, storage and marketing of produce. Methods: A study was conducted by collecting information from 240 cotton growers of four blocks in Gajapati and Rayagada districts of Odisha. The opinion of cotton growing farmers on most important parameters of risk in cotton cultivation among climate, harvesting and post-harvest, marketing and socio economic was collected individually through a semi-structured schedule and analyzed. Result: The opinion of cotton growing farmers of South Odisha indicate that the initial heavy rainfall followed by insufficient pre-monsoon rain; the rat menace in storage; exploitation by the traders in marketing and lack of community organization for facilitation of cluster approach are the most important risk parameters that influence cotton cultivation.
Considerations in the Diagnosis and Treatment of Post-Traumatic Neuropathic Pain: A<strong> </strong>Narrative Review
Authors: Park Hyun-Jeong , Ahn Jong-Mo , Ryu Ji-Won 
Published: June 2024

This study aims to provide an updated overview of the systematic evaluation and management of Post-Traumatic trigeminal neuropathic pain (PTTN) resulting from dental procedures or trauma. PTTN arises following an injury to the trigeminal nerve, which is responsible for sensory and motor functions in the maxillofacial region. The etiology encompasses various dental procedures and craniofacial trauma, leading to a spectrum of symptoms, from tingling to severe pain. Diagnostic challenges stem from the absence of standardized criteria and the overlap with focal neuralgia, necessitating comprehensive evaluation. Misdiagnosis can result in prolonged suffering and unnecessary procedures. Successful management hinges on prompt diagnosis and interdisciplinary collaboration, with early intervention crucial in mitigating chronicity. While nerve recovery post-trauma is challenging, preventive measures through accurate evaluation and treatment are paramount. Management for PTTN includes non-invasive and surgical interventions. Non-invasive intervention includes systematic and local pharmacological management. This review enhances uniformity in PTTN evaluation and treatment approaches despite standardized study limitations.
Transforming Rural Governance through Enhanced Communication Strategies for Global Impact
Authors: Sindiana Dina Ayu , Rodiyah Isnaini 
Published: June 2024

This study explores the implementation challenges of a Website-Based Village Information System in Dukuhsari Village Government, focusing on communication, resource allocation, disposition, and bureaucratic structure. Through qualitative methods including interviews and observation, the study reveals gaps in communication and resource management, impacting the system's effectiveness. The findings emphasize the need for improved communication strategies, consistent training, and ongoing support to optimize the system's utility and enhance public service delivery in Dukuhsari Village.

Highlight:

Challenges in Village Information System Implementation: Communication and resource allocation.
Improving System Efficiency: Enhanced communication strategies and consistent training.
Impact on Governance: Transparency and accessibility in rural service delivery.

Keyword: Village Information System, Implementation Challenges, Communication, Resource Allocation, Public Service Delivery
A Simulator Based on Coupling of Reaction Transport Model and Multiphase Hydrate Simulator and Its Application to Studies of Methane Transportation in Marine Sediments
Authors: Liu Haotian , Zhang Jiecheng , Lu Hailong 
Published: June 2024

SummaryMethane emissions at seafloor are generally associated with the upward methane migration from the deeper sediments, partly from hydrate dissociation. The anaerobic oxidation of methane (AOM) occurring in the surface sediments acts as an important barrier to methane emissions, caused by the reaction between sulfate ions and dissolved methane molecules. However, the current hydrate simulators rarely consider the transport of sulfate and the subsequent AOM reaction. In this study, to investigate AOM effects in hydrate systems, a new simulator named Tough+Hydrate+AOM (THA) is developed by combining the reaction transport model (RTM) with the widely used Tough+Hydrate (T+H) simulator. The THA simulator is validated using the single-phase cases of the Dvurechenskii mud volcano in Black Sea since the results obtained are in good agreement with previous ones. This simulator is then applied to investigate the response of a hydrate reservoir offshore West Svalbard to seasonal seafloor temperature change and also to confirm its adaptability in multiphase hydrate systems. The results obtained suggest that the AOM filter efficiency is as low as 5%, meaning that the majority of methane released from hydrate dissociation in the deeper sediments will escape into the ocean. The THA simulator considering AOM is expected to be an important tool for assessing methane emissions caused by hydrate destabilization.
UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signaling
Authors: Wang Penghua , Harrison Andrew , Yang Duomeng , Cahoon Jason , Geng Tingting , Cao Ziming , Karginov Timofey , Chiari Conner , Li Xin , Qyang Yibing , Vella Anthony , Fan Zhichao , Vanaja Sivapriya Kailasan , Rathinam Vijay , Witczak Carol , Bogan Jonathan 
Published: June 2024

Abstract

The cytoplasmic RIG-I-like receptors (RLRs) recognize viral RNA and initiate innate antiviral immunity. RLR signaling also triggers glycolytic reprogramming through glucose transporters (GLUTs), whose role in antiviral immunity is elusive. Here, we unveil that insulin-responsive GLUT4 inhibits RLR signaling independently of glucose uptake in adipose and muscle tissues. At steady state, GLUT4 is docked at the Golgi matrix by ubiquitin regulatory X domain 9 (UBXN9, TUG). Following RNA virus infection, GLUT4 is released and translocated to the cell surface where it spatially segregates a significant pool of cytosolic RLRs, preventing them from activating IFN-β responses. UBXN9 deletion prompts constitutive GLUT4 trafficking, sequestration of RLRs, and attenuation of antiviral immunity, whereas GLUT4 deletion heightens RLR signaling. Notably, reduced GLUT4 expression is uniquely associated with human inflammatory myopathies characterized by hyperactive interferon responses. Overall, our results demonstrate a noncanonical UBXN9-GLUT4 axis that controls antiviral immunity via plasma membrane tethering of cytosolic RLRs.
ExGRS: exome-wide genetic risk score to predict high myopia across multi-ancestry populations
Authors: Su Jianzhong , Yuan Jian , Qiu Ruowen , Wang Yuhan , Chen Zhen Ji , Sun Haojun , Dai Wei , Yao Yinghao , Zhuo Ran , Li Kai , Xing Shilai , Yu Xiaoguang , Qiao Liya , Qu Jia 
Published: June 2024

Abstract

High myopia (HM), characterized by severe myopic refractive error, stands as a leading cause to visual impairment and blindness globally. HM is a multifactorial ocular disease and presents high heterogeneity in genetics. Employing a genetic risk score (GRS) is useful for capturing genetic susceptibility to HM. Incorporating rare variations into GRS assessment, though presents methodological challenges, yields significant benefits. This study enrolled two independent cohorts: 12,000 unrelated individuals of Han Chinese ancestry from Myopia Associated Genetics and Intervention Consortium (MAGIC) and 8,682 individuals of European ancestry from UK Biobank (UKB). Using whole-exome sequencing (WES) data, we first estimated the heritability of HM resulting in 0.53 (standard error, 0.06) in the MAGIC cohort and 0.21 (standard error, 0.10) in the UKB cohort. In the MAGIC cohort, rare variants in low linkage disequilibrium (LD) with neighboring variants were enriched for heritability, particularly for rare deleterious protein-altering variants. Thus, we generated, optimized and validated an exome-wide genetic risk score (ExGRS) for HM prediction by combining rare risk genotypes with common variant GRS (cvGRS). ExGRS improved the AUC from 0.819 (cvGRS) to 0.856 for HM. Individuals with a top 5% ExGRS conffered a 15.57-times (95%CI, 5.70 - 59.48) higher risk for developing HM compared to the remaining 95% of individuals in MAGIC cohort and 2.03 times (95%CI, 1.65-2.49) higher risk in UKB. Our study implies that rare variants are a major source of the missing heritability of HM in Han Chinese ancestry. And ExGRS provides an enhanced accuracy for HM prediction, shedding new light on research and clinical practice.
The Effect of Artificial Oocyte Activation on Embryomorphokinetic Parameters and Blastulation Time
Authors: Gode Funda , Pala İbrahim , Tamer Burcu , Işık Ahmet Zeki 
Published: June 2024

Abstract

Purpose
Does artificial oocyte activation (AOA) with calcium ionophore (Cai) application affect embryomorphokinetic parameters and clinical pregnancy outcomes?
Methods
This retrospective cohort study investigated if AOA with Cai affects the embryomorphokinetic parameters and clinical pregnancy outcomes of 413 patients. A total of 225 patients underwent intracytoplasmic sperm injection (ICSI) + AOA and 187 patients underwent only ICSI at Izmir University of Economics between 2018–2020.
Results
There were no significant differences between groups in terms of baseline parameters. When the duration from 2PN to tb (time to blastulation) was examined, t2, t3, t4, or t5 times were not significantly different between the groups that received and did not receive AOA treatment. Ca ionophore application was found to extend cavitation time and tb (p < 0.05). Optimal time lapse parameters (t5, cc2, S2 and t5-t2) also did not differ between two groups. There were no significant differences between groups according to embryo grades which were determined by optimal time lapse parameters. According to the fertilization and pregnancy results, no significant differences were found between the two groups.
Conclusions
Ca ionophore application does not seem to affect most of the embryomorphokinetic parameters except blastulation time. The clinical importance of this finding needs further research.
Factors Shaping Public Support for More Carbon Capture and Storage Projects in the United States
Authors: Fikru Mahelet G. , Nguyen Nhien 
Published: June 2024

Abstract

This study contributes to the literature examining public acceptance of carbon capture and storage (CCS) projects in the US. The examination of factors that shape public support for CCS projects provides policymakers with insights to address public concerns, balance CCS development with public sentiments, and make informed decisions about optimal locations and timing. Based on a nationally representative survey on 1,850 respondents, the study finds that in the US, there is very low familiarity (6.4%) regarding CCS technology and some limited opposition (11.5%) to increased CCS development. Regression results suggest that support for increased CCS projects in the US is influenced by perceptions of technical and social risks (leakage and community danger, respectively) but not cost of living risks, perceptions of environmental and economic benefits, familiarity with the technology, confidence in government regulations, and a desire for the US to lead in CCS. We fail to find the ‘Not-in-My-Backyard’ effect, and individuals supporting the development of more CCS in their states also support it at a national level. Understanding these factors helps policymakers anticipate challenges in implementing CCS initiatives and allows for the development of strategies to address concerns.
Acaricides in Agriculture: Balancing Livestock Health and Environmental Well-being in Tans- Nzoia County, Kenya.
Authors: Sifuna Douglas Bukhebi , Pembere Anthony , Lagat Silas , Barasa Godfrey , Manda Timothy , Ngeno Emily , Ssebugere Patrick , Nagawa Christine Betty , Kyarimpa Christine , Omwoma Solomon 
Published: June 2024

Abstract

Extensive use of chemicals in food production, although useful, has serious implications. Acaricides, which are extensively used to control ticks and mites in livestock farming, can leave harmful residues that pose risks to unintended organisms such as plants, insects, people, and other animals. Thus, limiting non-target exposure to acaricides is critical. The purpose of this study was to assess acaricide knowledge, use, and disposal methods among farmers and agrochemical dealers in Trans Nzoia County, Kenya, which is well-known for livestock farming. A purposive survey of stakeholders, including 100 farmers and 45 agrochemical shop attendants, revealed concerning practices. The findings revealed insufficient personal protection during acaricide application, with a minority of responders using gloves (33%,), safety goggles (0%), masks (42%), or overalls (51%) for agrochemical dealers and gloves (8%), overalls (48%), safety goggles (2%), and masks (28%) for farmers. Furthermore, used acaricide containers and residues were not properly disposed of after spraying, potentially contaminating water sources, soil, and plants. Insects, particularly bees and house flies, were spotted consuming leftovers from unprotected disposal sites and thereby entering food webs. Furthermore, animal drying sections in spraying regions included grass, giving animals the opportunity to ingest residues. Recommendations include improved acaricide monitoring and management by extension field staff, as well as educating farmers and pesticide dealers about health concerns, proper disposal techniques, and the importance of wearing personal protective equipment. To effectively limit dangers, a regulation requiring agrochemical dealers to sell acaricides together with protective gear is recommended.
Phase and Amplitude Simultaneously Coding Metasurface with Multi-frequency and Multifunctional Electromagnetic Modulations
Authors: Cai Chengxin , Li Yinfei , Li Mingxing , Qin Yao , Zhou Yangyang 
Published: June 2024

Abstract

The integration of multiple functionalities into a single, planar, ultra-compact metasurface has presented significant opportunities for enhancing capacity and performance within compact 5G/6G communication systems. Recent advances in multifunctional metasurfaces have unveiled comprehensive wavefront manipulations utilizing phase, polarization transmission/reflection, and coding apertures. Despite these developments, there remains a critical need for multifunctional metasurfaces with expanded channel capabilities, including multiple operational frequencies, minimal crosstalk, and high-efficiency computable array factors. This study introduces a multifunctional metasurface that integrates phase- and amplitude simultaneous coding meta-atoms at dual frequencies. By altering the polarization of electromagnetic (EM) waves, it is possible to reshape the wave-fronts of reflected waves at these frequencies. The coding metasurface proficiently manipulates both x and y linearly polarized waves through phase and amplitude coding at dual frequencies, thereby enabling distinct functionalities such as anomalous reflection, reflection imaging, and vortex wave beam generation. Both theoretical analysis and full-wave simulation confirm the anticipated functionalities of the designed devices, paving the way for advancements in integrated communication systems with diverse functionalities.
The intrinsic association between somatic symptoms and psychiatric symptoms among Chinese COVID-19 inpatients: A network analysis
Authors: Gao Xing , Ren Lei , Yang Mengyuan , Chang Lingdi , Zhang Jinliang , Yu Yongcai , Zhang Chao , Meng Xiangliang , Huang Xunmei , Li Sikai , Shi Zhaokun , Xu Jing , Qin Weijun , Zhang Keying , Cheng Rui 
Published: June 2024

Abstract

Background
COVID-19 stands as the most impactful global public health event in the 21st century, affecting both physical and mental well-being. However, the connection between various somatic and psychiatric symptoms remains unclear. The purpose of the survey is to investigate the relationship between somatic and psychiatric symptoms.
Methods
The study involved 534 Chinese hospitalized COVID-19 patients. Self-evaluation of somatic symptoms in COVID-19 inpatients, patient health questionnaire-9, insomnia severity index, and the PTSD checklist-civilian version were used to quantify the levels of somatic, depression, insomnia, and post-traumatic stress disorder, respectively. The network analysis method by the R program was used to judge the bridge symptoms and the network differences by gender.
Results
In this survey, the depression-somatic symptom network revealed seven robust edges, including “Anosmia”-“Ageusia”, “Headache”-“Muscle pain”, “Stuffy nose”-“Cough”, “Cough”-“Anhedonia”, “Cough” - “Sleep”, “Cough”-“Fatigue”, and “Muscle pain”-“Fatigue”. The insomnia-somatic symptom network highlighted five robust edges, including “Sleep onset”-“Maintenance”, “Noticeability”-“Distress”, “Ageusia”-“Anosmia”, “Headache”-“Muscle pain”, and “Stuffy nose”-“Cough”. The PTSD-somatic symptom network featured five prominent edges, including “Ageusia”-“Anosmia”, “Headache”-“Muscle pain”, “Reminders avoidance”-“Thoughts avoidance”, “Hypervigilance”-“Startle”, and “Stuffy nose”-“Cough”. Simultaneously, “Cough”、“Anhedonia”、 “Noticeability”、“Libido loss” and “Sleep” as bridge factors linked somatic symptoms with psychiatric symptoms. No gender differences in the somatic- psychiatric symptoms network.
Conclusions
This study provides new perspectives for assessing and intervening in COVID-19 and other multisystem diseases.