bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetically Determined Serum Levels of Mannose-Binding Lectin Correlate Negatively with Common Carotid Intima-Media Thickness in Systemic Lupus Erythematosus
Authors: TROELSEN LONE N. , GARRED PETER , CHRISTIANSEN BURIS , TORP-PEDERSEN CHRISTIAN , JACOBSEN SØREN 
Published: July 2010

Objective.Patients with systemic lupus erythematosus (SLE) have excess cardiovascular morbidity and mortality due to accelerated atherosclerosis that cannot be attributed to traditional cardiovascular risk factors alone. Variant alleles of the mannose-binding lectin gene (MBL2) causing low serum concentrations of functional mannose-binding lectin (MBL) are associated with SLE and development of atherosclerosis. Recent studies show that these variant alleles are associated with increased risk of arterial thrombosis and cardiovascular disease in patients with SLE. Intima-media thickness of the common carotid artery (ccIMT) is a validated noninvasive anatomic measure of subclinical atherosclerosis. In a cross-sectional study we examined the relation among ccIMT,MBL2genotypes, and serum concentrations of MBL.Methods.TheMBL2extended genotypes (YA/YA, YA/XA, XA/XA, YA/YO, XA/YO, YO/YO) and serum concentrations of MBL were determined in 41 outpatients with SLE. ccIMT was measured by means of ultrasonography. Traditional and nontraditional cardiovascular risk modifiers were assessed and controlled for.Results.Using nonparametric Mann-Whitney tests we found a significant difference in ccIMT between low-expressing (XA/XA+YA/YO+XA/YO+YO/YO) and high-expressing (YA/YA+YA/XA)MBL2genotypes (p = 0.034). The difference in ccIMT remained significant in multivariable analysis adjusting for traditional and nontraditional cardiovascular risk modifiers (p = 0.049). ccIMT was negatively correlated to serum concentrations of MBL (Spearman rho = −0.33, p = 0.037). This relation also remained significant in multivariable analysis (p = 0.042).Conclusion.In this group of SLE patients,MBL2low-expressing genotypes and low serum levels of MBL were correlated with ccIMT, independent of the effects of traditional and nontraditional cardiovascular risk modifiers.
Gold‐Catalyzed Synthesis of Bicyclo[3.2.0]heptenes via a Formal [3+2]/[2+2]‐Annulation of Allylsilane with 4‐Methoxybut‐2‐yn‐1‐ols
Authors: Yang Chun‐Yao , Wang Chiou‐Dong , Tian Shu‐Fan , Liu Rai‐Shung 
Published: July 2010

AbstractThis work reports the novel gold‐catalyzed [3+2]/[2+2]‐annulation of allylsilane with 4‐methoxybut‐2‐yn‐1‐ols that yields highly strained bicyclo[3.2.0]heptene products efficiently and stereoselectively.
ChemInform Abstract: Identification and Synthesis of Vesperal, the Female Sex Pheromone of the Longhorn Beetle Vesperus xatarti.
Authors: BOYER F.‐D. , MALOSSE C. , ZAGATTI P. , EINHORN J. 
Published: July 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Acute myocardial infarction and anorexia nervosa
Authors: Abuzeid Wael , Glover Christopher 
Published: July 2010

AbstractObjective:A case of acute myocardial infarction (AMI) in a patient with anorexia nervosa is presented.Method:Clinlcal records, electrocardiogram, echocardiogram and coronary angiogram data of a patient with anorexia nervosa, presenting with AMI were evaluated. A Pubmed literature search was used to review cardiac complications of anorexia nervosa.Results:The patient presented with an anterior ST elevation AMI. She underwent emergent coronary angiography with successful reperfusion of a 100% occluded proximal left anterior descending coronary artery.Discussion:Anorexia nervosa is an eatlng disorder affectlng mainly female adolescents. Eating disorders carry the highest mortality rate compared to other psychiatric conditions (Caslero and Frishman, Cardiol Rev 14, 227‐231, 2006). It is reported that 80% of patients with an eating disorder are affected by a cardiac complication. Sudden cardiac death secondary to arrhythmia is often the cause of death in these patlents (Caslero and Frishman, Cardiol Rev 14, 227‐231, 2006). AMI is rarely described as a cardiac presentation in this patient population. Int J Eat Disord 2011. © 2010 by Wiley Periodicals, Inc.
Hydrogen Adsorption in Polyoxometalate Hybrid Compounds Based on Porous Metal‐Organic Frameworks
Authors: Ma Fengji , Liu Shuxia , Liang Dadong , Ren Guojian , Zhang Chundane , Wei Feng , Su Zhongmin 
Published: July 2010

AbstractTwo polyoxometalate hybrid compounds based on porous metal‐organic frameworks (PMOFs/POMs) have been prepared by lithium ion exchange and their crystal structures, stabilities and gas adsorption properties have been characterized. Both compounds consist of neutral Cu3(BTC)2 (BTC = 1,3,5‐benzentricarboxylate) metal‐organic frameworks (MOFs) as hosts and Keggin polyoxometalates (POMs) anions and lithium ions as guests with the MOFs maintaining their permanent porosity. H2 adsorption studies demonstrated that the guests play a key role in increasing the H2 adsorption capacity of the frameworks. With the introduction of POMs and lithium ions, the compounds not only display strong hydrogen adsorption behavior, but also exhibit some differences in H2 binding energy.
Vibrational properties of Cs4W11O35 and Rb4W11O35 systems: high pressure and polarized Raman spectra
Authors: da Silva K. Pereira , Paraguassu W. , Maczka M. , Filho A. G. Souza , Freire P. T. C. , Filho J. Mendes , Hanuza J. 
Published: July 2010

AbstractCs4 W11O35 (CW) and Rb4 W11O35 (RW) belong to the class of hexagonal bronzes whose structure originates from the KxWO3 superconductor hexatungstate. Charge‐imbalanced tungsten bronzes are dielectric materials with rich polymorphism, ferroelectric properties and second‐harmonic generation. In this work, we report the polarized Raman spectra results for both CW and RW, as well as results of high‐pressure Raman scattering experiments (0.0–11.0 GPa) for the Cs4 W11O35 system, in which we have observed two structural phase transitions at ∼4 and 7.5 GPa. We discuss these transformations and polarized Raman spectra on the basis of lattice dynamics calculation in the related system KNbW2O9. Polarized Raman spectra provide strong indication that the highest wavenumber modes observed in these systems originate from tungsten or oxygen vacancies. The observation of a soft‐like mode indicates that the observed phase transitions exhibit a displacive‐type behavior, thus further indicating that these transformations are likely related to reorientations of the octahedral units. The soft mode nature is discussed as well.PACS: 77.80.Bh; 78.30.Hv; 78.30.‐j. Copyright © 2010 John Wiley & Sons, Ltd.
Mehr als nur Rost
Authors: Pitzer Ulrike , Schneider Volker 
Published: July 2010

AbstractMit einem Bedarf von über einer Million Tonnen gehören synthetische Eisenoxide mit Abstand zur größten Gruppe der Buntpigmente. Trotz der seit über hundert Jahren im technischen Maßstab betriebenen Synthese sind Eisenoxidpigmente immer noch eine anspruchsvolle Produktgruppe.
Anorganische Chemie 2007
Authors: von Hänisch Carsten , Scheschkewitz David 
Published: July 2010

AbstractHauptgruppenelementverbindungen mit Anwendungspotenzial stehen weiter im Fokus – unter anderem stabile niedervalente Verbindungen und Mehrfachbindungssysteme. Bauarbeiten am Fundament und an der Spitze kennzeichnen die Entwicklung der Koordinationschemie im letzten Jahr. Eisenzeit herrscht in der Bioanorganik: Die Zahl der Publikationen zu biologisch relevanten Eisenverbindungen steigt rasant.
Theoretische Chemie 2007
Authors: Zipse Hendrik 
Published: July 2010

AbstractIn der theoretischen Homogenkatalyse dominieren Studien zu mechanistischen Details, Studien zur Vorhersage von Reaktivitäten oder Selektivitäten sind seltener. Quantendynamische Methoden ermöglichen die Beschreibung von Quanteneffekten in zunehmend komplexeren molekularen Systemen. Molekulardynamik‐Simulationen an biomolekularen Systemen produzieren heute Ergebnisse mit einer Genauigkeit ähnlich dem Experiment.
Umweltchemie 2007
Authors: Lammel Gerhard , Endres Felix , Goss Kai‐Uwe , Palm Wolf‐Ulrich , Bester Kai , Kreuzig Robert , Müller Susanne , Zachmann Dieter , Knacker Thomas , Lamshöft Marc , Schäffer Andreas 
Published: July 2010

AbstractIn der Atmosphäre, in Oberflächen‐ und Meerwasser, auch in Regionen fernab der Zivilisation finden Umweltforscher immer wieder bisher nicht nachgewiesene Chemikalien, aktuell unter anderem Flammschutzmittel, Textilhilfsmittel und Pestizide. Gegenstand bodenchemischer Forschungsaktivitäten sind vermehrt bioaktive Substanzen, insbesondere Veterinärpharmaka.
“70 Prozent unserer Produkte sind Green Chemistry”
Authors: Remenyi Christian 
Published: July 2010

AbstractZukunftsgeschäft und traditionelle Chemie – die Süd‐Chemie vereint dies mit ihren beiden Geschäftsfeldern Katalysatoren und Adsorbentien. Die Nachrichten aus der Chemie sprachen mit Günter von Au, dem Vorstandsvorsitzenden des Unternehmens.
Gesunde Ernährung ‐ multimedial und interaktiv
Authors: Schunk Axel 
Published: July 2010

AbstractWie viel der Mensch wovon essen sollte, ist auf Internetseiten und CD zu finden. Zudem bieten viele Medien tiefergehende Informationen über Lebensmittel und deren physiologische Verwertung im Körper.
Chemische Forschung ist Spitze
Authors: Hopf Henning 
Published: July 2010

AbstractDie GDCh war Mitinitiator des Forschungsratings und hat sich dafür eingesetzt, dass die Chemie in die Pilotstudie aufgenommen wird. Prof. Henning Hopf bewertet die Ergebnisse der Pilotstudie Forschungsrating aus Sicht der GDCh:
Systematisch Fehler finden
Authors: Beinert Wolf‐Dieter , Rösslein Matthias , Rezzonico Sergio 
Published: July 2010

AbstractDie Messunsicherheit eines komplexen Analysenverfahrens lässt sich mit Softwareunterstützung einfach und schnell beziffern – wie die Bestimmung von Di‐n‐butylphthalat in Polyvinylchlorid zeigt.
Dynamische Differenzkalorimetrie und Glasübergang
Authors: Höhne Günther W. H. , Kunze Wolfgang 
Published: July 2010

AbstractViele organische und makromolekulare Stoffe neigen dazu, bei Abkühlung glasig zu erstarren. Beim Erwärmen erweichen die Materialien in einem Temperaturbereich und verändern dabei ihre Materialeigenschaften. Kenntnisse über diesen Glasübergang haben in Materialkunde, Pharmazie und Lebensmitteltechnik praktische Bedeutung.
Studying the mechanism of thioketone‐mediated polymerization via electrospray ionization mass spectrometry
Authors: Günzler Fabian , Junker Tanja , Barner‐Kowollik Christopher 
Published: July 2010

AbstractThe polymeric product spectrum generated in thioketone‐mediated free radical polymerization (TKMP) was analyzed via electrospray ionization mass spectrometry. Poly(n‐butyl acrylate) samples were synthesized in the presence of the (commercially available) thioketone 4,4‐bis(dimethylamino)thiobenzophenone under variable reaction conditions in toluene solution at 80 °C. To unambiguously assign the mass spectra, the samples are prepared under variation of the monomer (going from n‐butyl acrylate to ethyl acrylate) as well as by employing variable thermally decomposing initiators [i.e., 2,2′‐azoisobutyronitrile and azobis(cyclohexanecarbonitrile)]. In all mass spectra, significant amounts of the expected cross‐termination product, formed via bimolecular termination of propagating macroradicals with the dormant thioketone radical adduct (consisting of a propagating chain and the mediating thioketone) alongside conventional termination products can be identified. As the study was carried out on acrylate polymers, acrylate‐specific reaction products arising from intramolecular transfer reactions followed by β‐scission of the generated mid‐chain radicals are also identified in the mass spectra. In addition, a species congruent with the dormant thioketone radical adduct itself (oxidized to its cationic state) was identified. Products that could potentially be formed via a chain transfer mechanism cannot be identified. The results presented here thus support the earlier suggested TKMP mechanism involving a highly stabilized adduct radical which undergoes significant cross‐termination reactions. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 1864–1876, 2009
Applications of information theory in ensemble data assimilation
Authors: Zupanski Dusanka , Hou Arthur Y. , Zhang Sara Q. , Zupanski Milija , Kummerow Christian D. , Cheung Samson H. 
Published: July 2010

AbstractWe apply information theory within an ensemble‐based data assimilation approach and define information matrix in ensemble subspace. The information matrix in ensemble subspace employs a flow‐dependent forecast error covariance and it is of relatively small dimensions (equal to the ensemble size). The information matrix in ensemble subspace can be directly linked to the information matrix typically used in non‐ensemble‐based data assimilation methods, such as the Kalman Filter (KF) and the three‐dimensional variational (3D‐Var) methods, which provides a framework for consistent comparisons of information measures between different data assimilation methods.We evaluate information measures, such as degrees of freedom for signal, within the Maximum Likelihood Ensemble Filter (MLEF) data assimilation approach and compare them with those obtained using the KF approach and the 3D‐Var approach. We assimilate model‐simulated observations and use the Goddard Earth Observing System Single Column Model (GEOS‐5 SCM) as a dynamical forecast model.The experimental results demonstrate that the proposed framework is useful for comparing information measures obtained in different data assimilation approaches. These comparisons indicate that using a flow‐dependent forecast error covariance matrix (e.g. as in the KF and the MLEF experiments) is fundamentally important for adequately describing prior knowledge about the true model state when calculating information measures of assimilated observations. We also demonstrate that data assimilation results obtained using the KF and the MLEF approach (when ensemble size is larger than 10 ensemble members) are superior to the results of the 3D‐Var approach. Copyright © 2007 Royal Meteorological Society
Higher‐order corrections for Rossby waves in a zonal channel on the β‐plane
Authors: Heifetz E. , Paldor N. , Oreg Y. , Stern A. , Merksamer I. 
Published: July 2010

AbstractA formal analytic perturbation expansion in the β term is carried out for the Rossby wave solution of the shallow‐water equations in a zonal channel on the β‐plane. Apart from a quantization of the meridional wave number, the presence of zonal boundaries alters, to first order, both the velocity and the geopotential structures of the wave but does not alter the phase speed of the wave. The ageostrophic component of the velocity field is identical in first order with that of the unbounded β‐plane and is therefore not related to the presence of boundaries. In contrast, the first‐order correction to the geostrophic velocity component is inherently related to the presence of walls as it ensures the vanishing of the total meridional velocity on the boundaries. This first‐order correction to the geostrophic field yields only a third‐order correction in the Rossby phase speed, as can be expected from symmetry considerations. Copyright © 2007 Royal Meteorological Society
Variable cirrus shading during CSIP IOP 5. II: Effects on the convective boundary layer
Authors: Marsham J. H. , Blyth A. M. , Parker D. J. , Beswick K. , Browning K. A. , Corsmeier U. , Kalthoff N. , Khodayar S. , Morcrette C. J. , Norton E. G. 
Published: July 2010

AbstractA combination of radiosonde, wind‐profiler and aircraft observations, together with large‐eddy modelling, show that shading from orphaned cirrus anvils had significant effects on the boundary layer during CSIP IOP 5. The control of boundary‐layer development by the cirrus shading, and the subsidence induced by the cirrus cover, led to a boundary layer that, at an aircraft altitude of around 500 m, was less turbulent, 0.8 g kg−1 drier and 0.3 K warmer under thick cirrus than in clear skies. In addition, at the top of the boundary layer, turbulence persisted for some time after the onset of cirrus shading, allowing continued entrainment and so stabilization of the previously well‐mixed boundary layer. These effects, which would have inhibited convective initiation under the cirrus, are consistent with the results of the first part of this study (Marsham et al., 2007).Power spectra show that, while vertical velocities were dominated by variations on the scale of the boundary‐layer depth, for water‐vapour mixing ratios and potential temperatures, mesoscale variations were comparable or dominant. In some cases a spectral gap is observed between these two scales of contributions. Radiosonde data and modelling show that, in addition to the variations in the boundary layer caused by the variable cirrus cover, pre‐existing variations in lid strength and boundary‐layer moisture were also significant on this day. These water‐vapour variations are also detectable in retrievals of total‐column water vapour from Global‐Positioning‐System data. Copyright © 2007 Royal Meteorological Society
Influence of the Quasi‐Biennial Oscillation on the ECMWF model short‐range‐forecast errors in the tropical stratosphere
Authors: Žagar Nedjeljka , Andersson Erik , Fisher Michael , Untch Agathe 
Published: July 2010

AbstractThis paper addresses the impact of the Quasi‐Biennial Oscillation (QBO) on the background‐error covariances in the tropical atmosphere of the ECMWF model. The tropical short‐range‐forecast‐error covariances are represented in terms of equatorial waves coupled to convection.By comparing the forecast‐error proxy data from two different phases of the QBO, it is shown that the phase of the QBO has an effect on the distribution of tropical forecast‐error variances between various equatorial waves. The influence of the QBO is limited to the stratospheric levels between 50 hPa and 5 hPa. In the easterly QBO phase, the percentage of error variance in Kelvin waves is significantly greater than in the westerly phase. In the westerly phase, westward‐propagating inertio‐gravity waves become more important, at the expense of Kelvin modes, eastward‐propagating mixed Rossby‐gravity waves and inertio‐gravity modes. Comparison of datasets from two easterly phases shows that the maxima of stratospheric error variance in various equatorial modes follow the theory of the interaction of waves with descending shear zones of the horizontal wind.Single‐observation experiments illustrate an impact of the phase of the QBO on stratospheric analysis increments, which is mostly seen in the balanced geopotential field. Idealized 3D‐Var assimilation experiments suggest that background‐error statistics from the easterly QBO period are on average more useful for the multivariate variational assimilation, as a consequence of a stronger mass‐wind coupling due to increased impact of Kelvin waves in the easterly phase.By comparing the tropical forecast errors in two operational versions of the model a few years apart, it is shown here that recent model improvements, primarily in the model physics, have substantially reduced the errors in both wind and geopotential throughout the tropical atmosphere. In particular, increased wind‐field errors associated with the intertropical convergence zone have been removed. Consequently, the ability of the applied background‐error model to represent the error fields has improved. Copyright © 2007 Royal Meteorological Society
Influences of ozone depletion, the solar cycle and the QBO on the Southern Annular Mode
Authors: Roscoe Howard K. , Haigh Joanna D. 
Published: July 2010

AbstractWe present results of multiple regressions of the leading mode of atmospheric variability at southern high latitudes: the Southern Annular Mode (SAM). It is regressed against indices with large interannual variability, and one of several trend indices in order to determine which trend term gives the optimum fit. We use SAM in sea‐level pressure from station data in order to provide a long time series, from 1957 to 2005. The regression indices are stratospheric volcanic aerosol, solar activity, the quasi‐biennial oscillation (QBO), the El Niño–Southern Oscillation, together with either a linear trend, or the effective equivalent stratospheric chlorine (EESC) that depletes polar ozone, or ozone mass deficit (OMD) in the Antarctic vortex. We find a statistically significant signal for volcanic aerosol, and, when the solar and QBO indices are represented by their product, a highly significant response to the product. We find a significant linear trend in SAM, but there is a major increase in significance using EESC2 and a further increase using OMD. We make no direct attempt to identify cause and effect, but if the trend is due to human influence then ozone loss is at least 9 times more likely the principle cause of the trend in SAM than greenhouse gases, although we do not exclude greenhouse gases making a smaller contribution. Monthly and seasonal regressions show a maximum correlation with OMD between December and May (summer and autumn), consistent with previous work on stratospheric change as a cause of change in the troposphere. Copyright © 2007 Royal Meteorological Society
Is Hypoalbuminemia an Independent Prognostic Factor in Patients with Gastric Cancer?
Authors: Crumley Andrew B. C. , Stuart Robert C. , McKernan Margaret , McMillan Donald C. 
Published: July 2010

AbstractBackgroundStudies have indicated that hypoalbuminemia is associated with decreased survival of patients with gastric cancer. However, the prognostic value of albumin may be secondary to an ongoing systemic inflammatory response. The aim of the study was to assess the relation between hypoalbuminemia, the systemic inflammatory response, and survival in patients with gastric cancer.MethodsPatients diagnosed with gastric carcinoma attending the upper gastrointestinal surgical unit in the Royal Infirmary, Glasgow between April 1997 and December 2005 and who had a pretreatment measurement of albumin and C‐reactive protein (CRP) were studied.ResultsMost of the patients had stage III/IV disease and received palliative treatment. The minimum follow‐up was 15 months. During follow‐up, 157 (72%) patients died of their cancer. On univariate analysis, stage (p < 0.001), treatment (p < 0.001), albumin level (p < 0.001), and CRP level (p < 0.001) were significant predictors of survival. On multivariate analysis, stage (p < 0.001), treatment (p < 0.001), and CRP level (p < 0.001) remained significant predictors of survival. Albumin was no longer an independent predictor of survival.ConclusionsLow albumin concentrations are associated with poorer survival in patients with gastric cancer. However, the strength of this relation with survival is dependent on the presence of a systemic inflammatory response, as evidenced by an elevated CRP level. Therefore, it appears that the relation between hypoalbuminemia and poor survival is secondary to that of the systemic inflammatory response.
Developing a Successful Robotic Surgery Program in a Rural Hospital
Authors: Zender John , Thell Christina 
Published: July 2010

AbstractRobotic surgery has become a standard in many large hospitals across the United States and the world. The surgical robot offers the surgeon a three‐dimensional view and increased dexterity in addition to providing the benefits of laparoscopic surgery to the patient (eg, shorter hospital stays, decreased pain, fewer postoperative complications). The next progression for robotic surgery is a move to rural venues. For many small, rural hospitals, however, obtaining a robot may be cost prohibitive, and these facilities may need to explore sources of funding for the program. Developing a robotics program requires intense training by surgeons and all surgical team members. Effective marketing of the program and the dedication and hard work of surgical team members and administrators are vital to ensure the success of the program.