bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroleptic Malignant Syndrome - review of pathophysiology, clinical presentation, differentiation and management
Authors: Strus Karolina , Madera Magdalena , Dąbrowska Natalia , Mazur Sylwia , Zdunek Roksana , Mazur Agata , Nagórska Emilia , Marcinkowski Krzysztof , Bizan Aleksy , Kublińska Aleksandra 
Published: May 2024

Introduction and purpose: The number of invented and produced medications has increased over recent years. Besides their positive impact on health, they invariably provide various kinds of side effects. This review is focused on malignant neuroleptic syndrome, a rare condition with no fully confirmed pathogenesis, which at least partially can be explained as an adverse effect of blocking dopamine receptors. Even though it usually affects psychiatric or neurological patients, doctors of all medical specializations should stay alert, as the condition can often lead to premature death.
Brief description of knowledge: The main symptoms associated with NMS are hypertonia, hyperpyrexia, autonomic instability and altered consciousness. They can appear in any configuration, sometimes followed by less characteristic manifestations. It should be primarily differentiated from serotonin syndrome, malignant hyperpyrexia and catatonia, mostly through the interview of those who have taken medications and undergone surgeries, as there are not any specific lab tests available. Fundamental treatment methods consist of neuroleptic withdrawal, intensive supportive care, drug administration and eventually ECT.
Summary: NMS is an uncommon, severe disease that should be carefully considered in patients treated with neuroleptics. Due to its rarity and sudden onset, it appears to be problematic to conduct widespread research and studies, so there are still no concrete, consistent and unquestioned guidelines on recognizing and treating the condition.
Current approach to diagnosing and treating necrotizing fasciitis
Authors: Ciulkiewicz Łukasz , Kryszpin Paulina , Jachimowski Piotr , Pełka Maciej , Kania Anna , Fijałkowska Justyna 
Published: May 2024

Introduction: Necrotizing fasciitis is an infrequent yet highly fatal bacterial infection characterized by widespread necrosis of fascia and subcutaneous fat tissue. Though initial symptoms resemble typical infection, necrotizing fasciitis progresses rapidly triggering acute phase response. Individuals with advanced age, chronically ill, immunocompromised, or abusing alcohol are especially susceptible to developing necrotizing fasciitis. In order to reduce mortality, early diagnosis and appropriate treatment are indispensable.
Aim of the Study: Aim of this study is through evaluating existing literature to outline the contemporary diagnostic strategies and emerging therapy options for necrotizing fasciitis.

Description of the State of Knowledge: Primary diagnostic methods involve clinical evaluation and surgical exploration, complemented by fresh frozen sections for rapid diagnosis and the finger test. Diagnostic imaging incorporates the use of magnetic resonance imaging, computed tomography and ultrasound. The treatment is mostly centered around surgical debridement and antibiotic therapy. Therapies that display potential efficacy include low-dose radiotherapy, hyperbaric oxygen therapy, and the use of intact fish skin grafts for tissue reconstruction after successful treatment. The emerging approach includes therapy targeting systemic inflammatory response syndrome, sepsis induced coagulopathy and critical illness related corticosteroid insufficiency.

Conclusions: The management of necrotizing fasciitis primarily depends on traditional methods. Fast identification and proper treatment are pivotal in reducing the mortality rate. Recognizing the significance of addressing the acute phase response in necrotizing fasciitis treatment introduces new possibilities for therapeutic interventions. Further research is vital to evaluate the existing approaches to necrotizing fasciitis management and explore new diagnoistic and therapeutic alternatives.
Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori–Infected Patients Undergoing Upper Endoscopy
Authors: Epplein Meira , McCall Shannon J. , Wang Frances , Alagesan Priya , Brown HannahSofia , Wawrzynski Joseph , Labriola Caroline , Zuzul Rachel , Cook Christian , Dillon Melanie , Hyslop Terry , Patierno Steven R. , Salama Nina R. , Garman Katherine S. 
Published: May 2024

INTRODUCTION:
We designed a race-conscious study to assess the presence of Helicobacter pylori virulence factor cagA in a retrospective cohort of patients with active H. pylori infection.

METHODS:
We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019.

RESULTS:

H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001).

DISCUSSION:
Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
Coronary Revascularisation in Heart Failure with Reduced Ejection Fraction
Authors: Haring Bernhard , Böhm Michael 
Published: May 2024

The role of myocardial revascularisation in patients suffering from ischaemic cardiomyopathy with extensive coronary artery disease and heart failure with reduced ejection fraction (HFrEF) remains controversial. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are considered revascularisation procedures. Evidence prior to the latest medical treatment advances only suggests a long-term benefit of CABG over pharmacological therapy in this population. When angina-related symptoms dominate patients’ lives despite optimal medical treatment, PCI can be considered if the patient is ineligible for CABG after carefully weighing up the perioperative risk. Viability and/or ischaemia detection to guide revascularisation have been unable to accurately predict treatment effects of CABG or PCI. Optimal heart failure treatment should be initiated in all patients presenting with ischaemic cardiomyopathy and HFrEF as the first and most important measure to improve long-term prognosis.
Movilidad urbana insertada en la planificación de ciudades más justas y sostenibles
Authors: Diniz César Augusto de Oliveira , Garçon Luis Fernando Passarela , Molina Junior Vitor Eduardo , Freiria Rafael Costa 
Published: May 2024

El objetivo principal de este trabajo es discutir la importancia de la movilidad urbana en la creación de políticas públicas de planificación para el desarrollo social, económico y ambiental de las ciudades, especialmente en los países subdesarrollados, donde existen desigualdades en el acceso a los medios de transporte y las oportunidades disponibles. Se utilizó una metodología de revisión de literatura para relevar el tema en la literatura y comprender el marco regulatorio existente en el país, que también fue objeto de análisis. Los Objetivos de Desarrollo Sostenible (ODS) fueron abordados como una de las guías para identificar y priorizar necesidades locales y establecer metas y estrategias. El texto también destaca la importancia de los transportes alternativos y activos, como el caminar y la bicicleta, para hacer las ciudades más accesibles, saludables y sostenibles para la población. Es importante que la planificación considere la infraestructura necesaria para garantizar la seguridad y comodidad de los peatones, incluyendo aceras bien señalizadas, iluminadas y seguras, además de áreas de esparcimiento y sociales. Dentro de las alternativas de micromovilidad urbana, la decisión de optar por caminar y utilizar la bicicleta está relacionada con las motivaciones y barreras de cada individuo, para lo cual se necesitan políticas e infraestructura que la hagan atractiva. El texto, en términos de resultados, encuentra que Brasil cuenta con legislación específica para la planificación urbana, como el Estatuto de la Ciudad y la Política Nacional de Movilidad Urbana, que representan avances institucionales en la búsqueda de una movilidad más accesible, segura y sostenible, siendo el principal desafío es la implementación de los instrumentos presentes en estos marcos normativos.
Los impactos de las tarifas gratuitas en el transporte público: una revisión sistemática y lexicográfica
Authors: Oliveira Matheus Duarte de , Faria Beatriz Oliveira Leles de , Almeida Cristiano Farias 
Published: May 2024

El interés en la implementación del arancel libre es un tema creciente en Brasil hoy en día. Por lo tanto, este artículo tiene como objetivo analizar la evolución y los principales discursos sobre el tema. Para este análisis, utilizamos como metodología el análisis sistemático de la literatura con un enfoque cuantitativo y cualitativo. Se seleccionaron 43 artículos con el tema central del estudio de la tarifa gratuita o subsidiada, para ello se utilizó la base de datos ScienceDirect y las siguientes palabras clave: "tarifa gratuita" y "transporte público". El contenido textual fue sometido a análisis descriptivo a través de Excel y a un análisis textual lexicográfico utilizando el software IRAMUTEQ. Se identificaron cinco clases: servicio de transporte público competitivo, mejor servicio para atraer al usuario, bienestar social para usuarios mayores, gestión de viajes en horas punta y cambio en el comportamiento de los usuarios de bajos ingresos. Por lo tanto, es posible inferir que los autores creen en el impacto social y el aumento de los viajes en función del cambio en el precio de las tarifas del transporte público
Proyecto de accesibilidad en vías y espacios públicos: aplicación de metodología en el barrio de Bauru, São Paulo
Authors: Plotze Ariane Roberti , Furegatti Simone Andrea , Oliveira Neto Luttgardes de 
Published: May 2024

La situación municipal de movilidad necesita ser evaluada constantemente por el poder público del municipio ya que la población no utiliza solo el centro de la ciudad. El 'Núcleo Residencial Ernesto Geisel', un barrio ya desarrollado, mantiene escuelas, jardines infantiles, clínicas de salud y comercio diversificado y evolucionado, permitiendo a los residentes no tener que viajar a otras partes de la ciudad. Dada la importancia de la construcción de espacios accesibles para la mayor integración de la población local, se realizó un estudio de la legislación vigente en materia de accesibilidad con el fin de obtener una evaluación clara de los aspectos físicos de la región, a partir del estudio de los puntos positivos y negativos de los espacios públicos. A partir de estos estudios, se propusieron intervenciones de diseño y correcciones de acuerdo con las Normas Técnicas de ABNT, concomitantemente con la elaboración de un proyecto arquitectónico-paisajístico-urbano con el objetivo de eliminar barreras arquitectónicas, promover una circulación sin interferencias y de manera segura, a través de intervenciones en los caminos, carreteras y accesos a dispositivos y espacios públicos instalados en la región. Además de la recogida de datos y material fotográfico, el contacto con los usuarios a partir de cuestionarios sirvió de subvención para la elaboración del proyecto final.
Síndrome Respiratória Aguda Grave por Covid-19: internações em Unidade de Terapia Intensiva nas regiões de saúde do estado do Pará, 2020-2022
Authors: Américo Xavier Larissa , Paes Santos Neto Carlos Alberto , Rodrigues Pinheiro Rosiane , Da Silva Sousa Júnior Alcinês , Mourão de Sousa Alder 
Published: May 2024

Este estudo objetivou analisar a disponibilidade e ocupação dos leitos de unidade de terapia intensiva (UTI) para covid-19, entre as regiões de saúde do estado do Pará, no período de 2020 e 2022. Trata-se de um estudo ecológico, transversal, realizado com dados secundários. Coletou-se dados mensais de casos e óbitos de acordo com a data dos primeiros sintomas de síndrome respiratória aguda grave (SRAG), por município de residência no estado do Pará, as internações por local de internação, tipo de leito, nos anos de 2020, 2021 e 2022, sistematizou-se de acordo com as 13 regiões de saúde do estado do Pará. Com esses dados calculou-se letalidade e prevalência e taxa de ocupação em UTI. Para estimar as chances de internações em leitos de UTI com as comorbidades utilizou-se odds ratio, com intervalo de confiança de 95%. Analisou-se a correlação linear simples seguida do teste de Person, para comparação da prevalência por mês e por região de saúde com a respectiva taxa de ocupação em leito de UTI. Em relação ao percentual de leitos de UTI e o uso de suporte ventilatórios observou-se heterogeneidade entres as regiões de saúde. Nas regiões sem leitos de UTI, a letalidade foi maior. Desse modo, fica evidente como algumas regiões estão mais homogêneas que outras, fazendo-se necessárias pactuações entre essas para possibilitar transferência de pacientes. Conclui-se que a heterogeneidade na disponibilização de leitos de UTI nas regiões de saúde do Pará impactou na oferta de serviços, tratamento e sobrevida por covid-19.

Palavras-chave: COVID-19; Coronavírus Relacionado à Síndrome Respiratória Aguda Grave; Unidades de Terapia Intensiva UTI; Planejamento Regional de Saúde.
STRATEGI MEMBANGUN BUDAYA MADRASAH UNGGUL DI MADRASAH ALIYAH AL-IRTIQO INTERNATIONAL ISLAMIC BOARDING SCHOOL (IIBS) MALANG
Authors: Marifatul Hasanah Siti , Widiastuti Ika , Mubin Syahrul 
Published: May 2024

Tujuan penelitian ini adalah untuk memahami core value dalam membangun budaya madrasah unggul, peran dan strategi kepala madrasah untuk mewujudkan budaya madrasah unggul. Jenis penelitian ini adalah kualitatif, dengan menggunakan metode wawancara, observasi dan dokumentasi. Penelitian dilaksanakan di Madrasah Aliyah Al-Irtiqo’ International Islamic Boarding School (IIBS) Malang. Adapun hasil dari penelitian adalah: 1) Core values budaya unggul MA Al Irtiqo’ meliputi nilai unggul, keadilan dan kesetaraan, tanggung jawab, mandiri dan berprestasi, religius, akhlakul karimah dan berpedoman al Quran dan sunnah, kesetiaan, sosial dan kerjasama. 2) Peran kepala MA Al Irtiqo’ dalam membangun dan mengembangkan budaya unggul memposisikan diri sebagai educator, supervisor, leader, inovator, creator, motivator dan inovator. 3) Strategi dalam membangun dan mengembangkan budaya sekolah unggul meliputi: Perencanaan pengembangan nilai nilai unggul sekolah berdasarkan visi, misi dan tujuan sekolah, pemantapan core value (nilai dasar) budaya sekolah, pemantapan leadership, manajerial dan meingkatkan SDM sekolah, penyusunan nilai, spirit dan norma di sekolah, menyusun program unggulan sekolah, sosialisasi, implementasi, penguatan dengan reward dan punishment, dan evaluasi dan feed back.
PERAN PENGAWAS MADRASAH DALAM PENILAIAN KINERJA KEPALA MADRASAH DI KABUPATEN BLITAR
Authors: Hasan Abdur Rosyid , Bachtiar Firdaus Ahmad , Nur Efendi  
Published: May 2024

Performance assessment of madrasah principals is important to be carried out as a form of evaluation so that it can foster the seriousness of madrasah principals to improve the quality of performance, quality of service, and other progressive efforts. The research has a descriptive qualitative approach with a field study. The research data were collected using interview techniques, as well as documentation, and then analyzed using an interactive model. The results showed that madrasah supervisors in the Blitar district conducted annual and four-year performance assessments of madrasah principals. The assessment starts from the preparation stage by providing instruments and media for uploading documents to madrasah principals, the implementation stage with document verification and madrasah visits, at the reporting stage, the assessment results are given to the head of the madrasah education section at the District Ministry of Religious Affairs Office and the Head of Madrasah Education Division at the Provincial Ministry of Religious Affairs Office. Cooperation by all parties in the madrasah will greatly help the assessment process run smoothly, but in its implementation, there are also inhibiting factors such as lack of resources, lack of understanding of the assessment criteria, and the number of madrasahs supervised by one madrasah supervisor.
AUGMENTED REALITY TECHNOLOGY FOR VISUALIZING DIPANEGARA UNIVERSITY BUILDINGS
Authors: Parera Josseano Amakora Koli , Maulidyanto Tommy 
Published: May 2024

Multimedia technology continues to advance, one of which is Augmented Reality (AR) technology, commonly known as the technology for merging virtual objects into the real world. Building brochures, which only display building photos and are visible from only one side, require us to visit the building to view its structure. Therefore, an idea emerged for a design of an application that uses Android-based Augmented Reality technology. This application allows users to view a more realistic physical shape of the building without visiting it directly by directing the camera towards a marker displaying the building's logo and showing a 3D model of the Dipanegara University building. It also provides general information about the building. This application is designed using 3DS Max, Unity, and Vuforia SDK, making it easier for prospective students to view the building's layout.

Keywords : 3DS Max, Android, Augmented Reality, Unity, Visualization.
MINE SLOPE DESIGN SIMULATIONS USING SLIDE 6.0 SOFTWARE OF POST-MINING SLOPE STABILITY
Authors: Norfaeda Rahma , Maulidyanto Tommy , Kartini  
Published: May 2024

Post-mining slopes are susceptible to landslides due to factors such as slope geometry, rock structure, physical and mechanical properties of rocks, and groundwater content. Monitoring of these slopes is essential to prevent broader environmental issues. This research aims to determine the stability of former mining slopes using soil samples from the Mataraman District, Banjar Regency. The technical analysis method focuses on the physical and mechanical properties of soil, supplemented with mine slope design simulations using Slide 6,0 software to ascertain the safety factors from various slope angles. Safety factor analysis considers the smallest cohesion and bulk density values to represent the material strength of the slope. Findings indicate that the post-mining slopes would remain stable and safe provided no additional destabilizing factors are introduced. The slopes maintain a safety factor greater than 2, implying stability even with a steepness up to 70°.

Keywords: mining slope stability, safety factor
Formation of Three-Dimensional Thinking as one of the Significant Professional Qualities of an Architect
Authors: Zvyagintseva M. M. , Kuznetsov M. E. , Gladskikh A. A. 
Published: May 2024

The article touches upon the problems of the professional formation of an architect, the development of his three-dimensional thinking in the process of studying the disciplines of the artistic cycle. The architect's vision must meet the strict requirements imposed by the specifics of visual activity, the laws of figurative literacy and the tasks of a particular stage of work, correlate with the ultimate ideals and purpose of creative activity. In the study of light as a means of artistic expression, an important role must be given to the psychology of the perception of light in nature and in the image. Only having a developed three-dimensional thinking a student can convincingly and accurately convey the character of a three-dimensional shape, its plasticity and movement.The recognition of three-dimensional forms, including natural objects based on three-dimensional vision of images, through an accurate assessment of light and shadow gradations, adequate transfer of color phenomena of reality to the possibilities of the visual sphere and skillful modeling of forms depicted by light and shadow, becomes an emphasis in the training of an architect. The position of color in the image of shapes in space is no less significant.Pedagogical techniques for the formation of three-dimensional thinking of students and the development of their graphic skills in drawing three-dimensional objects, including architectural ones, are based on scientific discoveries of scientists, scientists and artists since the Renaissance.The integrity of perception, attention to detail, the study of space, understanding of form, possession of means of shaping and the image of a three-dimensional object in a two-dimensional format are becoming universal criteria that allow us to talk about the high-quality training of future architects.
Bibliometric Analysis of Scientific Publications on Communicative Behavior Problems
Authors: Gorbacheva A. S. , Kazaryan M. Yu. 
Published: May 2024

Purpose of research. The purpose of the study is to analyze the dynamics of the publication activity of scientific research in the field of studying communicative behavior. Communicative behavior is an object with an interdisciplinary research status. It falls into the area of research interest of various scientific fields. A bibliometric analysis of publication activity was carried out in connection with solving several tasks: to find out areas of knowledge in which the greatest publication activity is concentrated, to study the methods that are used in various fields of communicative behavior analysis, to identify organizations that are included in this research search.Methods. The study was conducted in two scientific electronic databases: the Russian Scientific Electronic Library Elibrary.ru and the international open platform for researchers and scientific organizations Lens. The bibliometric analysis was used as the research method. It involves the quantification of documentary information flows and it is based on quantitative research indicators reflecting the state of science as a whole or its individual branches.Results. As a result of the bibliometric analysis of publication activity on the problems of scientific research in the field of communicative behavior, communicative behavior in the digital environment and communicative behavior in social networks, a significant increase in publication activity was revealed in both international and Russian information databases over the past 10 years (2013 - 2023). It is also noted that the predominant number of publications on the issues studied is concentrated in the field of psychology. However, we can trace a shift in the focus of foreign research on communicative behavior towards digitalization in information technology, and Russian research towards the field of digital technologies in the educational environment.Conclusion. The results obtained indicate the high relevance, as well as the scientific and practical significance of the research topic on the problems of communicative behavior in general, as well as communicative behavior in the digital environment and social networks, in particular.