bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peningkatan Keterampilan Passing Bawah Bola Voli Siswa Kelas X Melalui Model Pembelajaran Project Based Learning
Authors: Agustini Raaiyatini Mariani , Basuki Sunarno , Mashud Mashud , Pebriyandi Pebriyandi , Ridha Sahbana 
Published: April 2024

Tujuan studi. Tujuan penelitian ini meningkatkan keterampilan passing bawah dengan menggunakan model Project Based Learning (PjBL).
Bahan dan metode. Rancangan penelitian model Kurt Lewin merupakan rancangan penelitian yang digunakan terdiri dari empat tahapan yaitu, perencanaan, pelaksanaan, observasi dan refleksi. Subjek penelitian adalah peserta didik Kelas X SMKN-1 Pandih Batu yang berjumlah 15 orang. Objek penelitian untuk meningkatkan keterampilan passing bawah bolavoli dengan menggunakan model Project Based Learning (PjBL). Instrumen yang digunakan dalam penelitian ini adalah Instrumen tes ujuk kerja keterampilan passing bawah. Analisis data yang digunakan adalah analisis kuantitatif dan kualitatif deskriptif.
Hasil. Berdasarkan analisis data menunjukkan hasil pembelajaran passing bawah bolavoli menunjukkan adanya peningkatan keterampilan passing bawah bolavoli. Hal ini ditunjukkan pada siklus I hanya 9 orang atau 60% peserta didik yang tuntas dan 6 orang atau 40% peserta diddik yang tidak tuntas selanjutnya pada siklus II terdapat peningkatan dari 15 orang peserta didik 11 orang atau 73% peserta didik yang tuntas dan 4 orang atau 27% peserta didik yang tidak tuntas.
Kesimpulan. Capaian hasil belajar keterampilan passing bawah bolavoli terlihat peningkatan dari siklus I dan siklus II dengan menggunakan model Pembelajaran passing bawah bolavoli meningkat secara keseluruhan.
Reduction of Power Distribution System Losses by Using Novel Heuristic Algorithm
Authors: Qadeer Ul Hassan, Nasrullah Khan Muhammad Shakeel, Ali Arshad, 
Published: April 2024

The Distribution Networks are the most widespread part of electrical power systems. Researcher has been trying to in the solutions to reduce high energy losses associated with them due to the low voltage level of the supply framework. Capacitors based techniques have been proposed to reduce these losses. These techniques minimize power losses, improve stability, and enhance the voltage profile of the distribution system under normal operating conditions. Finding optimal place and proper size of the capacitor is still a very hot area of research. In this research work, an innovative procedure based on the Archimedes optimization Algorithm (AOA) is presented to solve the optimal capacitor placement as well as sizing problem to improve the voltage profile and reduce the energy losses in the network. The suggested AOA based technique, is implemented on IEEE 33 bus network to find the optimal locations to place the capcitors in the distribution network. The performance of AOA is also compared with a standard model to verify the effectiveness of the scheme. By using AOA active power losses reduced upto 23.62% and reacrive losess by 21.86% respectively. The simulation results reveal that AOA based technique offer better results regarding the capacitor placement for voltage profile improvement of buses and significant reduction in active power losses as comapred to previous studies.
Topographical features of the formation of outflow tracts with the use of spongy allo-drainages in glaucoma
Authors: Kornilaeva G. G. , Musina L. A. , Kornilaeva M. P. , Shangina O. R. 
Published: April 2024

PURPOSE. Improving the results of the operation and achieving its reliability in secondary glaucoma, including refractory glaucoma, can be done using a non-biodestructible allograft drainage with spongy structure fabricated by Alloplant® technology.METHODS. Experimental and morphological studies conducted in the Russian Eye and Plastic Surgery Center showed that the allogeneic spongy biomaterial used for anti-glaucoma sponge drainage surgery is gradually replaced by loose tissue with a porous structure, similar to trabecular, forming a new drainage system. During the operation, the proximal part of the drainage is inserted through the excised drainage zone in the anterior chamber angle (ACA). The distal part is tucked into the suprachoroidal space through a linear incision in the scleral bed.RESULTS. The newly created topography of the ACA after sponge drainage operation with the use of allogeneic biomaterial features not only the expansion of the ACA profile, but also the replacement of the excised part of the drainage zone with biomaterial after sinus trabeculectomy (STE) and elimination of retention of the intraocular fluid (IOF) outflow. Ultrasound biomicroscopy (UBM) performed at various times after antiglaucoma surgery showed that the microtubule system preserved. Optical coherence tomography (OCT) of the ACA demonstrates the location of the drainage in the long-term follow-up.CONCLUSION. Antiglaucoma operation with the use of allogeneic biomaterial with spongy structure promotes the formation of trabecula-like tissue in the ACA, eliminates retention of IOF outflow, and reduces the risk of scleroscleral and sclero-conjunctival adhesions.
The potential of a fixed combination of brimonidine and timolol in achieving safe intraocular pressure levels after micropulse laser cyclophotocoagulation
Authors: Alekseev I. B. , Berlova V. A. , Kuptsova V. A. , Alekseeva L. I. 
Published: April 2024

PURPOSE. To evaluate the clinical effectiveness and safety of using a fixed combination — hypotensive drug Brimonidine Duo (brimonidine tartrate 2 mg/mL + timolol maleate 5 mg/mL) to reduce intraocular pressure in patients with advanced stages of primary open-angle glaucoma (POAG) in cases when achieving target pressure failed after laser micropulse transcleral diode laser cyclophotocoagulation (mCPC).METHODS. MCPC was performed with individually chosen parameters in 100 patients (104 eyes) aged 35 to 86 with POAG, of them 54.17% were men and 45.83% were women. The follow-up period lasted 3 months, the results were evaluated on the 1st, 7th and 14th days, then after 1 and 3 months. In 23.08% of cases (24 patients) subjects were prescribed antihypertensive combination drug Brimayza Duo due to intraocular pressure (IOP) remaining uncompensated.RESULTS. The average IOP level after 7 days was 23.54± 4.8 mm Hg. After 3 months, IOP values were 18.11±2.04 mm Hg, which is 4–5 mm Hg lower than in the early postoperative period. After 30 days of follow-up, an additional antihypertensive drug Latanoprost 0.005% was added for 5 patients (20.83%). Repeated surgery was recommended and performed in 4 patients (16.67%), of which 1 patient underwent surgical intervention of the penetrating type, 3 patients underwent repeat mCPC with individually chosen parameters.CONCLUSION. MCPC is a safe and effective tool for reducing intraocular pressure in patients with advanced stages of POAG. The noninvasive nature of this technique makes it possible to speed up the recovery time after surgery, as well as reduce the number of postoperative complications. Among patients who failed to achieve target pressure after surgery, the use of Brimayza Duo was effective in 62.5% of cases.
Age-related increase in lens thickness and changes in the profile of anterior chamber angle in patients with moderate and high axial hyperopia
Authors: Kolenko O. V. , Sorokin E. L. , Pashentsev Ia. E. , Samokhvalov N. V. 
Published: April 2024

PURPOSE. To determine the age-related increase in lens thickness (LT), decrease in anterior chamber depth (ACD) and anterior chamber angle (ACA) in patients with short axial length (APA) of the eyes.METHODS. The study included 100 patients (200 eyes) with short AL (23 mm or less), with a transparent lens or with initial stage of age-related cataract: 46 men and 54 women, aged 19 to 85 years. The LT and ACD, ACA parameters were assessed using optical coherence tomography.RESULTS. In the total population of patients, LT increased by an average of 32 μm per year. At the same time, ACD and ACA decreased by an average of 14 µm and 0.3° per year, respectively (p<0.001). In men, LT increased by 35 μm per year, while in women it increased by 29 μm per year, the difference was not statistically significant (p=0.071). But the decrease in ACA in men averaged 0.38° per year, while in women it was 0.23° per year, this difference was statistically significant (p=0.003). In addition, the rate of decrease in the ACD in men and women also differed statistically significantly: 18 µm versus 11 µm per year (p=0.018).CONCLUSION. 1. According to our data, the annual increase in LT in eyes with short AL averages 32 μm, the decrease in ACD and ACA is on average 14 μm and 0.3° per year, respectively.2. We did not find a statistically significant gender difference in the rate of annual increase in LT, although the rate of decrease in ACA and ACD in men turned out to be statistically significantly higher.3. The obtained data on the annual changes in such morphometric parameters as LT, ACA and ACD in eyes with short AL are key in the formation of primary angle-closure glaucoma (PACG). It may allow a more precise prediction of the timeline of an increased risk of PACG in each particular case.
Surgical treatment of secondary glaucoma in comorbid pathology with subsequent penetrating keratoplasty (case study)
Authors: Starostina A. V. , Golovin A. V. , Burlakov K. S. , Sholokhova V. R. , Taevere M. R. , Troshina A. A. 
Published: April 2024

PURPOSE. To evaluate the effect of surgical treatment of secondary glaucoma with subsequent end-to-end keratoplasty in a patient with aphakia, operated retinal detachment and condition after intrastromal keratoplasty.METHODS. A patient with secondary refractory glaucoma against the background of aphakia, a biopolymer implant in the corneal stroma, an inflammatory reaction to multiple surgical interventions (formation of anterior synechiae), operated retinal detachment was examined in the S.N. Fedorov National Medical Research Center "MNTK "Eye Microsurgery" in Moscow. The following treatment was performed: implantation of Ahmed valve drainage and pene-trating keratoplasty with implant removal.RESULTS. On the second day after implantation of Ahmed valve drainage on the right eye, intraocular pressure was normal in palpatory examination, the drainage tube in the anterior chamber was in the correct position. Three months after the operation, there were no complaints, intraocular pressure was normal in palpatory examination, there was a decrease in corneal edema. Penetrating keratoplasty was performed four months after the implantation of Ahmed valve drainage. On the second day after the operation, hypotension was noted with palpatory measurement of intraocular pressure, which persisted for five days. At patient discharge, the graft was adapted, the sutures were consistent, normal pressure with palpatory examination. During the observation period of up to three months, visual acuity increased to 0.1.CONCLUSION. To prolong the hypotensive effect and minimize intra- and postoperative complications in order to achieve the highest possible visual functions before performing optical reconstructive surgery, it is advisable to perform an anti-glaucoma intervention. In secondary refractory glaucoma caused by various factors, the choice of surgical treatment is always individual and depends on the severity of anatomical changes, the experience and capabilities of the surgeon, and often requires multi-stage treatment with continuous observation.
The relationship of the metabolic syndrome and its correction with the development and progression of glaucoma
Authors: Makogon S. I. , Ivanova D. I. 
Published: April 2024

Glaucoma continues to be the leading cause of irreversible blindness worldwide. The main proven risk factor is elevated intraocular pressure. But questions remain on the impact of various somatic diseases and their correction on the course of glaucoma. This review provides information on the metabolic syndrome and considers some of its components and their correction in patients with glaucoma.The metabolic syndrome includes arterial hypertension, diabetes mellitus, dyslipidemia and obesity. The presented experimental and clinical studies show that the components of the metabolic syndrome correlate with glaucoma. Such components of the metabolic syndrome as arterial hypertension and diabetes mellitus are without doubt risk factors for the development of glaucoma. The opinions of researchers regarding whether obesity and dyslipidemia can also be considered risk factors are ambiguous. Recently, however, interest in them has increased due to in-depth study of the microbiome, since changes in it play a certain role in the development of neurodegenerative diseases of the central nervous system and the retina. Several studies have noted that being overweight and obese is associated with a risk of developing glaucoma. Indicators of lipid metabolism also showed a certain relationship with the risk of developing glaucoma. Treatment of lipid metabolism disorders commonly involves the use of statin drugs. Recent studies show that they may have more than just a hypolipidemic effect. A number of studies has demonstrated that the use of statins improves blood circulation and has a neuroprotective effect.
Trends in the surgical treatment of glaucoma in recent decades
Authors: Gusarevich A. A. , Kuroyedov A. V. , Brezhnev A. Y. 
Published: April 2024

The analysis of trends in the surgical treatment of primary open-angle glaucoma (POAG) allows assessing changes in the indications for surgical treatment, the number of glaucoma surgery and their modifications, as well as the demographic characteristics of patients, duration of preoperative therapy and the effectiveness of treatment.The results indicate that over the past 20 years in the Russian Federation there was a shift towards an increasingly long-term therapeutic strategy used before the surgical stage of treatment, and, in general, a decrease in the number of performed glaucoma surgeries. There is much concern about late surgical treatment, which is confirmed by the established increase in the age of first-time operated patients, and the tendency to increase the number of operations at a far advanced stage of the disease. Most of the published studies on the postoperative hypotensive efficacy of surgery are of limited duration, which does not allow an adequate assessment of the results of treatment. Early appointment of medical hypotensive therapy after surgical intervention indicates a low interaction between outpatient and inpatient specialists, which hinders the possibility of early correction of postoperative problems. The recent increase in the number of scientific works, especially patents, focusing on the search for new technologies that can be implemented in glaucoma surgery, the development of modern drainage devices and the methods for prolonging the hypotensive effect after surgery gives a reason for optimism. The performed analysis dictates the need to develop and implement measures aimed at clearly defined indications for timely surgical treatment and creation of conditions for a complex relationship between the patient, outpatient ophthalmologist and glaucoma surgeon.
Knowledge without Epistemology
Authors: Feyerabend Paul K. 
Published: April 2024

The universality of scientific principles, theories, laws is never purely “objective”, it has a strong anthropological component. A theory of knowledge invoking transhistorical agencies is therefore not only dead — it was never alive; its so-called successes are nothing but an immense chimera. Scientific research knows no universal boundary conditions or standards whether of a conventional, aprioristic, or empirical kind but uses and invents rules according to circumstance without regarding the selection as a separate “epistemic” act and often without realising that an important choice is being made.
Impact Of Pharmacist Led Therapeutic Drug Monitoring of Vancomycin in Pediatric Cancer Patients
Authors: Mazhar Saba , Akhtar Ali , Shirazi Ovais Ullah , Razaque Ghulam , Nisa Umda Tun , Akbar Zunaira , Bhutta Omer , Siddique Adeel 
Published: April 2024

Aim This study aimed to evaluate the dosing regimen and therapeutic drug monitoring of vancomycin in this patient population. Method The study included 100 pediatric patients (3 months to 15 years) with various gram-positive bacterial infections. All patients received the initial vancomycin dose of 15 mg/kg every 6 hours. The researchers evaluated the incidence of achieving desired trough levels with this dosing regimen. Results The results revealed that patients between 1.0 and 5.9 years of age were less likely to achieve the desired trough levels with the initial vancomycin dose. Consequently, dose adjustments were made for patients with sub-therapeutic trough levels. These adjustments involved a 25% increase in the vancomycin dose. Importantly, the study found that the higher vancomycin dosing did not have any harmful effects on kidney function in pediatric patients, and no significant adverse effects were observed. Conclusion The dosing regimen of 15 mg/kg every 6 hours was unlikely to achieve the desired trough concentrations in pediatric patients with complicated infections and oncological diseases. The study recommends dose adjustments for the treatment of different infections in this population to increase the likelihood of reaching therapeutic steady-state concentrations of vancomycin.
Hubungan Pola Asuh, Lingkungan Dan Stimulus Terhadap Kemandirian Dalam Hand Hygiene Pada Anak Pra-Sekolah Di TK Kristen Gideon Kalabahi Tahun 2022
Authors: Tanesib Veronika Vidensia 
Published: April 2024

Introduction: Independence is the ability of somebody to respond to what to do with a little help or without help from other people. Existing independence on self child age early could support them in self arrange alone like decision making, problem solution, self believe, social skills, and interpersonal intelligence. WHO considers cleanliness of hands very urgent so we set October 15th as the Day Hand Wash Worldwide. Report Riskesdas in 2018, population data were obtained Indonesia as much as 49,8% already have the habit of washing hands the right way. Purpose: for knowing connection pattern foster, environment, and stimulus to independence in hand hygiene on a child pre-Gideon Kalabahi Christian Kindergarten in 2022.
Methods: Research this use approach quantitative with design studies cross-sectional. Sample whole Gideon Kalabahi Christian Kindergarten student and the master totaling 80 respondents. Instrument use questionnaire as well as sheet observation.
Results: Test statistics chi-square obtained Mark p-value that is 0,003 <ꭤ= 0,05 there is a connection among pattern foster and independence in hand hygiene, there is the connection between the stimulus and independence in hand hygiene Mark p-value 0,007 <ꭤ= 0,05 and no there is connection Among environment and independence in hand hygiene Mark p-value is 0,021 <ꭤ= 0,05.
Discussion: Parents hope as a nanny first could control, guide, and accompany their son going to maturity, because its stimulation with method invites a child to play, sing, and various other activities as well as create a nice environment so that child could grow optimally.
INNOVATIVE TREATMENT TECHNOLOGIES IN THE SURGICAL UNIT OF THE REPUBLIC OF KAZAKHSTAN
Authors: Албаев Р.К. 
Published: April 2024

Целью работы является анализ состояния и оценка эффективности внедрения и использования инновационных лечебных технологий в условиях хирургической службы многопрофильной больницы. Материалами послужили данные Больницы Медицинского центра (БМЦ) Управления делами Президента Республики Казахстан за 2019-2021 годы по вопросам внедрения новых инновационных лечебных технологий в практику хирургической службы больницы. Методами исследования было изучение количества и структуры операций, выполненных в гибридной операционной с биплановой ангиографической системой, в центре роботизированной хирургии по клиническим профилям, в центре Сердца с использованием дифференцированного мультидисциплинарного подхода и кардиохирургических вмешательств по отделению рентгенхирургии. Дана оценка клинической эффективности всех инновационных лечебных технологий, используемых в хирургической службе. Полученные данные показали, что внедрение инновационных лечебных технологий в хирургической службе позволило расширить объемы и улучшить качество медицинской помощи. Основными направлениями развития инновационной деятельности явились гибридная операционная с биплановой ангиографической системой, лапароскопическая и миниинвазивная робот-ассистированная хирургия, методы, используемые в практике центров Сердца и рентгенхирургии. Внедренные инновационные лечебные технологии во всех случаях показали высокую клиническую эффективность.
The objective of the paper is to analyze the state and assess the effectiveness of the introduction and use of innovative treatment technologies in the surgical unit of a multifield hospital. The data of the Medical Center Hospital of the President’s Affairs Administration of the Republic of Kazakhstan, for 2019-2021 on the introduction of new innovative treatment technologies in the practice of the surgical unit of the Hospital was used as the materials. The research methods studied the number and structure of surgeries performed in the hybrid operating room with biplane angiographic system, robotic surgery center for clinical profiles, Heart Center using differentiated multidisciplinary approach and cardiac surgical interventions in the X-ray Surgery Department. The clinical effectiveness of all innovative treatment technologies used in the surgical unit was assessed. The data obtained showed that the introduction of innovative treatment technologies in the surgical unit allowed expanding the volume and improving the quality of medical care. The main areas of innovative development were hybrid OR, laparoscopic and minimally invasive robot-assisted surgery, methods used in the practice of Heart and X-ray surgery centers. The implemented innovative treatment technologies showed high clinical efficiency in all cases.