bluuebunny/crossref_metadata_2025_split huggingface dataset:
The first complete chloroplast genome of Thalictrum fargesii: insights into phylogeny and species identification
Authors: Chen Shixi , Safiul Azam Fardous Mohammad , Akter Mst. Lovely , Ao Li , Zou Yuanchao , Qian Ye 
Published: April 2024

IntroductionThalictrum fargesii is a medicinal plant belonging to the genus Thalictrum of the Ranunculaceae family and has been used in herbal medicine in the Himalayan regions of China and India. This species is taxonomically challenging because of its morphological similarities to other species within the genus. Thus, herbal drugs from this species are frequently adulterated, substituted, or mixed with other species, thereby endangering consumer safety.MethodsThe present study aimed to sequence and assemble the entire chloroplast (cp) genome of T. fargesii using the Illumina HiSeq 2500 platform to better understand the genomic architecture, gene composition, and phylogenetic relationships within the Thalictrum. Results and discussionThe cp genome was 155,929 bp long and contained large single-copy (85,395 bp) and small single-copy (17,576 bp) regions that were segregated by a pair of inverted repeat regions (26,479 bp) to form a quadripartite structure. The cp genome contains 133 genes, including 88 protein-coding genes (PCGs), 37 tRNA genes, and 8 rRNA genes. Additionally, this genome contains 64 codons that encode 20 amino acids, the most preferred of which are alanine and leucine. We identified 68 SSRs, 27 long repeats, and 242 high-confidence C-to-U RNA-editing sites in the cp genome. Moreover, we discovered seven divergent hotspot regions in the cp genome of T. fargesii, among which ndhD-psaC and rpl16-rps3 may be useful for developing molecular markers for identifying ethnodrug species and their contaminants. A comparative study with eight other species in the genus revealed that pafI and rps19 had highly variable sites in the cp genome of T. fargesii. Additionally, two special features, (i) the shortest length of the ycf1 gene at the IRA-SSC boundary and (ii) the distance between the rps19 fragment and trnH at the IRA-LSC junction, distinguish the cp genome of T. fargesii from those of other species within the genus. Furthermore, phylogenetic analysis revealed that T. fargesii was closely related to T. tenue and T. petaloidium.ConclusionConsidering all these lines of evidence, our findings offer crucial molecular and evolutionary information that could play a significant role in further species identification, evolution, and phylogenetic studies on T. fargesii.
Visitor characteristics and changes in mental health stigma after attending the Mind Space mental health experience exhibition
Authors: Ho Grace W. K. , Mui Jolene Hang Chun , Wong Raymond , Chien Wai Tong , Wong Kwan Ho , Bressington Daniel 
Published: April 2024

IntroductionMind Space is an experiential mental health exhibition in Hong Kong, aiming to raise public awareness and provide education regarding mental health. This prepost study aimed to 1) examine the relationships between visitors’ characteristics and their mental health stigma at baseline, and 2) provide a preliminary evaluation of the effectiveness of Mind Space in reducing stigma and promoting help-seeking attitudes toward mental health conditions.MethodsWe analyzed data from all consenting visitors who attended Mind Space between September 2019 and December 2021. Visitors’ attitudes toward mental health conditions and their willingness to seek professional psychological help were measured through online questionnaires before and after visits. Multiple linear regression was used to identify the demographic predictors of outcome variables at baseline. Changes in outcome variables after attending Mind Space were assessed using paired sample t-tests.ResultsA total of 382 visitors completed the baseline questionnaires, among which 146 also completed the post-test. At baseline, higher socioeconomic levels and personal contact with people with mental health conditions predicted more positive attitudes and understanding toward mental disorders. Tentatively, the results also showed that after attending Mind Space, a significant reduction in negative attitudes about mental illness (t=4.36, p=&lt;.001; d=.361) and improvements in the propensity to seek professional help (t=-5.20, p&lt;.001; d=-.430) were observed, along with decreases in negative attitudes toward stereotypes (t=4.71, p=&lt;.001; d=.421) and restrictions (t=2.29, p=.024; d=.205) among healthcare professionals.DiscussionOur findings highlight the need for mental health education for people with lower socioeconomic status and the importance of direct contact in public mental health education initiatives. The present study also suggests that Mind Space may be a useful model for public mental health education, but the exhibition requires further evaluation to ascertain if any reductions in stigma are maintained over time.
A comparison of visual attention to pictures in the Autism Diagnostic Observation Schedule in children and adolescents with ADHD and/or autism
Authors: Kochhar Puja , Arora Iti , Bellato Alessio , Ropar Danielle , Hollis Chris , Groom Madeleine (Maddie) J. 
Published: April 2024

BackgroundAttention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) are neurodevelopmental conditions which frequently co-occur. The Autism Diagnostic Observation Schedule (ADOS) is commonly used to aid with diagnostic assessment of ASD but was not originally designed for use in those with comorbid ADHD. Visual attention to social stimuli has been often studied in ASD using eye-tracking, to obtain quantitative indices of how attention is deployed to different parts of a social image/scene. As the ADOS includes tasks that rely on attending to and processing images of social scenes, these measures of visual attention could provide useful additional objective measurement alongside ADOS scores to enhance the characterisation of autistic symptoms in those with ADHD.MethodsChildren with ASD, comorbid ASD and ADHD, ADHD and Neurotypical (NT) controls were recruited (n=84). Visual attention was measured using eye-tracking during free viewing of social scenes selected from the ADOS. The full ADOS was then administered. Stimulant medication was temporarily withdrawn during this assessment. Research diagnoses were based on the Development and Wellbeing Assessment (DAWBA), ADOS, Social Communication Questionnaire (SCQ, a measure of ASD severity) and Conners’ Rating Scales (CRS-3, a measure of ADHD severity) following clinical consensus.ResultsUsing factorial ANOVAs to model ADHD, Autism and their interaction, we found that fixation duration to faces was reduced in those with ASD (ASD and ASD+ADHD) compared to those without ASD (ADHD and NT). Reduced visual attention to faces in the whole sample was associated with Autism symptom severity (SCQ subscale scores) but not ADHD symptom severity (CRS-3 scores).DiscussionOur findings provide preliminary evidence in support of implementing visual attention measurement during assessment of ASD in the context of comorbidity with ADHD. For example, if a child with ADHD was found to reduce attention to faces in ADOS pictures this may suggest additive difficulties on the autism spectrum. Replication across a larger sample would be informative. This work has future potential in the clinic to help with complex cases, including those with co-occurring ADHD and ASD.
Image sequence sorting algorithm for commercial tasks
Authors: Grelier Guillaume , Casal Miguel A. , Torrente-Patiño Alvaro , Romero Juan 
Published: April 2024

IntroductionThe sorting of sequences of images is crucial for augmenting user engagement in various virtual commercial platforms, particularly within the real estate sector. A coherent sequence of images respecting room type categorization significantly enhances the intuitiveness and seamless navigation of potential customers through listings.MethodsThis study methodically formalizes the challenge of image sequence sorting and expands its applicability by framing it as an ordering problem. The complexity lies in devising a universally applicable solution due to computational demands and impracticality of exhaustive searches for optimal sequencing. To tackle this, our proposed algorithm employs a shortest path methodology grounded in semantic similarity between images. Tailored specifically for the real estate sector, it evaluates diverse similarity metrics to efficiently arrange images. Additionally, we introduce a genetic algorithm to optimize the selection of semantic features considered by the algorithm, further enhancing its effectiveness.ResultsEmpirical evidence from our dataset demonstrates the efficacy of the proposed methodology. It successfully organizes images in an optimal sequence across 85% of the listings, showcasing its effectiveness in enhancing user experience in virtual commercial platforms, particularly in real estate.ConclusionThis study presents a novel approach to sorting sequences of images in virtual commercial platforms, particularly beneficial for the real estate sector. The proposed algorithm effectively enhances user engagement by providing more intuitive and visually coherent image arrangements.
Breakthroughs in satellite remote sensing of floods
Authors: J-P. Schumann Guy 
Published: April 2024

Flooding is among the top-ranking disasters worldwide, evident through frequent and devastating events causing significant localized impacts and broader repercussions. Floods lead to substantial insured and uninsured losses, with a few hundred billions of $US in flood-related losses over the last 5 years, only a moderate amount of which were insured. Remote sensing, especially via satellite technology, has great potential for flood mapping and monitoring. Although many initiatives utilize satellites for flood response, few have resulted in operational protocols for mandated response organizations. Historic breakthroughs in satellite remote sensing have occurred since the 1970s, with six major milestones enhancing flood monitoring over the last half century. This article looks back at these technological development breakthroughs and the barriers to progress they lifted. Advancements in machine learning, cloud computing, and increased satellite missions promise more developments. Anticipated innovations include satellite constellations with various sensors and self-learning processing models to relay real-time insights for disaster response. Looking forward, a transformative shift in flood mapping from space may be expected as early as 2025, driven by enhanced orbital computing for predictive capabilities, improving disaster preparedness and response.
Effects of sugar molecules on the rheological and tribological properties and on the microstructure of agarose-based fluid gels
Authors: Ghebremedhin Marta , Seiffert Sebastian , Vilgis Thomas A. 
Published: April 2024

Introduction: Fluid gels exhibit a unique flow behaviour. Their pronounced viscoelastic behaviour arises from irregular microgel particles, leading to plasticity and yielding, as well as a characteristic transition from a solid to a fluid-like state. This is defined by both the core and the surface structures of the particles. Adding co-solutes such as sucrose alters the network properties at the molecular scale, affecting texture and lubrication. This study investigates how the microscopic changes due to sucrose addition correlate with macroscopic changes.Material and methods: Agarose fluid gels with varying sucrose concentrations were prepared and studied using the rheometer. Temperature dependent viscosity behaviour during gelation under shear was investigated in situ. Light microscopy and particle size measurements were examined, and complemented by amplitude, frequency and flow sweeps as well as tribological studies. These tests allow us to understand the influence of sucrose on the particle network formation.Results and discussion: Sucrose concentration influenced the sizes, shapes, and interconnected network structure of the microgel particles. These microstructural changes are closely related to the dynamic competition between gelation and disruption of the agarose chains during shear, which directly influences the rheological and tribological properties of the resulting fluid gels. Additionally, the association of the agarose chains and their gelation process is also influenced depending on whether the sucrose or agarose was first dissolved in water. The experimental observations suggest specific molecular mechanisms, explaining the role of sucrose in structure formation of agarose-based fluid gels. These results have the potential to expand the applications of fluid gels, which play a crucial role in modifying the texture and flow behaviour of foods and beverages, particularly in addressing challenges such as dysphagia.
Diet quality and nutritional status of HIV-exposed children aged between 6 and 18 months in the Greater Accra Region of Ghana
Authors: Folson Gloria K. , Bannerman Boateng , Asante Millicent , Tokor Grace Siba , Ador Gabriel , Atadze Vicentia , Puplampu Peter , Dame Joycelyn Assimeng , Neizer Margaret , Yamauchi Futoshi 
Published: April 2024

IntroductionHIV-exposed children, even when uninfected, have a greater risk of malnutrition than unexposed counterparts. WHO guidelines recommend children aged 6–23 months be fed a variety of foods to meet nutrient requirements. This study aimed to determine infant and young child feeding (IYCF) practices among HIV-exposed children under 2 years old enrolled in a dietary intervention and to explore correlates of the IYCF indicators and associations between IYCF and nutritional status.MethodologySix hundred and eighty mother–child pairs were recruited from 19 health facilities from the Greater Accra Region. The sociodemographic data, anthropometry, hemoglobin, and dietary intake were recorded.ResultsNinety-five percent of HIV-positive mothers breastfed their babies, and 53% initiated breastfeeding in a timely manner. Around one in five mothers (21%) introduced liquids other than breastmilk to their children within the first 2 days of birth, and only around one in four children (26%) aged 12–23 months had received breast milk on the day before assessment. Ninety-three percent of babies between 6 and 8 months had been introduced to solid, semi-solid, or soft foods. Eighteen percent of children reached the threshold for Minimum Dietary Diversity (MDD) by eating from over five of eight food groups. Fifty-four percent received Minimum Meal Frequency (MMF), eating between 2 and 4 meals in a day. Eleven percent received the Minimum Acceptable Diet (MAD). Thirty-two percent were anemic. Underweight and stunting were 12 and 11%, respectively. Children of mothers aged 31–40 years were more likely to meet the MDD and MAD [OR = 2.8, 95%CI (1.185, 6.519), p &lt; 0.05 and OR = 2.8, 95%CI (1.256, 6.279), p &lt; 0.05] compared to children of mothers aged 30 years or less or aged above 40 years. Children from households earning more than GHS 500 were more likely to meet MMF than those from households earning less. No associations were found between IYCF and nutritional status.ConclusionFindings highlight the need for nutrition programs to educate HIV-exposed children’s caregivers on optimal feeding practices. The importance of continued breastfeeding and dietary diversity needs to be highlighted. Affordable, iron-rich foods should be promoted. Special attention should be paid to younger, less educated, and lower socioeconomic status mothers.
Molecular Prevalence, Genetic Diversity, and Tissue Tropism of Bartonella Species in Small Mammals from Yunnan Province, China
Authors: Han Pei-Yu , Xu Fen-Hui , Tian Jia-Wei , Zhao Jun-Ying , Yang Ze , Kong Wei , Wang Bo , Guo Li-Jun , Zhang Yun-Zhi 
Published: April 2024

Bartonella is an intracellular parasitic zoonotic pathogen that can infect animals and cause a variety of human diseases. This study investigates Bartonella prevalence in small mammals in Yunnan Province, China, focusing on tissue tropism. A total of 333 small mammals were sampled from thirteen species, three orders, four families, and four genera in Heqing and Gongshan Counties. Conventional PCR and real-time quantitative PCR (qPCR) were utilized for detection and quantification, followed by bioinformatic analysis of obtained DNA sequences. Results show a 31.5% detection rate, varying across species. Notably, Apodemus chevrieri, Eothenomys eleusis, Niviventer fulvescens, Rattus tanezumi, Episoriculus leucops, Anourosorex squamipes, and Ochotona Thibetana exhibited infection rates of 44.4%, 27.7%, 100.0%, 6.3%, 60.0%, 23.5%, and 22.2%, respectively. Genetic analysis identified thirty, ten, and five strains based on ssrA, rpoB, and gltA genes, with nucleotide identities ranging from 92.1% to 100.0%. Bartonella strains were assigned to B. grahamii, B. rochalimae, B. sendai, B. koshimizu, B. phoceensis, B. taylorii, and a new species identified in Episoriculus leucops (GS136). Analysis of the different tissues naturally infected by Bartonella species revealed varied copy numbers across different tissues, with the highest load in spleen tissue. These findings underscore Bartonella’s diverse species and host range in Yunnan Province, highlighting the presence of extensive tissue tropism in Bartonella species naturally infecting small mammalian tissues.
ANALISIS PENGENDALIAN PERSEDIAAN BERAS MENGGUNAKAN METODE SILVER-MEAL PADA PERUM BULOG KOTA SAMARINDA
Authors: Mubarog Resky , Wahyuda Wahyuda , Suh Utomo Dutho 
Published: April 2024

Salah satu cabang dari Perum Bulog ini berlokasi di Kota Samarinda. Perum BULOG Kota Samarinda memiliki permasalahan pada sistem pengendalian persediaan yaitu minimnya stok beras pada gudang. Membutuhkan metode pengendalian persediaan yang tepat untuk mengatasi ketersediaan beras sehingga meminimalisir terjadinya kekurangan beras saat dibutuhkan dan juga pada proses pemesanan. Setelah melihat plot data historis yang cenderung membentuk pola stationer, serta melakukan uji variabilitas dengan hasil lebih besar dari 0,25,sehingga data bersifat dinamis. Metode yang digunakan pada penelitian ini yaitu dengan perhitungan Peramalan (Forecasting), peramalan permintaan yang terpilih adalah moving Average pada rata rata bergerak pada 9 bulanan yang karena memiliki nilai error terkecil, yaitu MAD sebesar 26703,61, MSE sebesar 1698270204,17, dan MAPE sebesar 21,01%, didapat hasil peramalan untuk 12 periode kedepan diperkirakan sebesar 1.298.360 kg atau 25.968 sak. Pada pengendalian persediaannya menggunakan metode silver-meal menghasilkan frekuansi pemesanan sebanyak 24 kali dengan total penghematan sebesar 28,691% dan selisih Rp986.865,33 dari perusahaan.
PENGARUH TEKNIK SKIMMING DAN SCANNING TERHADAP KETERAMPILAN MEMBACA SISWA KELAS V PADA MATA PELAJARAN BAHASA INDONESIA DI SDN 9 PATOKAN KABUPATEN SITUBONDO TAHUN PELAJARAN 2023/2024
Authors: Rofek Aenor 
Published: April 2024

Tujuan dari penelitian ini adalah untuk mengetahui ada dan tidaknya Pengaruh Teknik Skimming dan Scanning terhadap keterampilan membaca siswa pada mata pelajaran Bahasa Indonesia kelas V semester ganjil di SDN 9 Patokan Kabupaten Situbondo Tahun Pelajaran 2023/2024.Dalam penelitian ini rancangan yang digunakan adalah eksperimen. Dengan membandingkan kelompok eksperimen dengan kelompok kontrol peneliti ingin mengetahui perbedaan antara variabel X dan variabel Y.Berdasarkan hasil perhitungan yang diperoleh harga t = 2,810 dilanjutkan harga t hitung dibandingkan dengan harga t tabel dengan taraf signifikan 5 % dan derajat kebebasan (db) = 38 adalah 0,312 sesuai dengan konsensus yang ada pada bab analisis data, ketentuan pengujian hipotesis adalah sebagai berikut : 1) Menerima hipotesis nihil (Ho) jika “t” hitung < “t” tabel ( t hitung lebih kecil dari t tabel ). 2) Menerima hipotesis kerja (Ha) jika “t” hitung > “t” tabel ( t hitung lebih besar dari t tabel ). Hasil perhitungan diperoleh harga t hitung adalah bila hasil ini dibandingkan dangan harga t tabel pad taraf signifikansi 5 % dan derajat kebebasan (db) = 38, maka harga t- hitung lebih besar dari t- tabel yaitu 2,810 > 0,312 hasil tersebut sesuai dengan konsensus nomer dua yaitu menerima hipotesa kerja. Berdasarkan keterangan di atas dapat disimpulkan bahwa ada perbedaan keterampilan membaca antara siswa yang belajar dengan Teknik Skimming dan Scanning dengan siswa yang belajar secara Konvensional pada mata pelajaran Bahasa Indonesia. Dengan demikian belajar dengan Teknik Skimming dan Scanning lebih baik dari pada belajar secara Konvensional.
Temozolomide on Aggressive Pituitary Adenomas: About 4 Cases and Review of the Literature
Authors: - Esma Kerboua , - Chahira Mazouzi , - Radia Benyahia , - L. Atroune , - F.Terkmani 
Published: April 2024

Pituitary adenomas represent 15 to 20% of all brain tumors . They affect 1/1000 of the world population, some pituitary adenomas with high Ki-67 indexes exhibit aggressive behaviors, such as rapid growth, early and frequent recurrence, and resistance to conventional treatment, even in the absence of metastasis . Many trials have focused on the role of chemotherapy in the treatment of these aggressive and atypical adenomas The objective: Monitoring of patients on temozolomide . we report the follow-up of 4 patients (pts) of 10 pts treated in
our department during the period (2012-2019), 2 women / 2 men presenting an aggressive pituitary macro-adenoma, having benefited from excision surgery, radiotherapy and received medical treatment with temozolomide initiated with clinical, biological and radiological evaluation of the therapeutic response and search for p53 and ki 67 in the diagnosis. A clinical improvement was noted in our 4 pts; Radiologically: a partial response was obtained in 1pts, two stabilities and one progression . The average duration of treatment is 26 months (12 - 40) with manageable side effects .Temozolomide appears to be effective in the treatment of aggressive pituitary adenomas and may currently constitute a therapeutic alternative when all resources are exhausted, thus allowing control of the disease.
Efeito de diferentes distúrbios antrópicos sobre assembleias de morcegos (Mammalia: Chiroptera) em um ecótono Cerrado-Amazônia
Authors: Moreira Martins Ana Carolina , Lopes Ferreira da Rocha Gabriel , Fernandes Magalhães de Oliveira Hernani 
Published: April 2024

A expansão das fronteiras agropecuárias é o principal vetor da perda de habitat naturais no mundo e a maior causadora de impactos sobre a biodiversidade até o ano de 2100, levando ao grande declínio de espécies nos trópicos. Devido Ã grande magnitude e velocidade da perda de habitat no arco do desmatamento (especialmente no Mato Grosso), é indispensável a análise dos efeitos de diferentes matrizes e distúrbios como o fogo, na biota das matas remanescentes. Nesse contexto, os morcegos são excelentes bioindicadores porque respondem a uma ampla gama de alterações antrópicas na qualidade do habitat. Assim, o presente estudo tem como objetivo testar diferenças nas assembleias de morcegos de fragmentos florestais sobre diferentes distúrbios (fogo e diferentes limites de borda com eucalipto e seringal). Em 2012, morcegos foram capturados por redes de neblina durante seis noites consecutivas em seis sítios: três fragmentos florestais sob diferentes distúrbios (fogo, eucalipto, seringal) e três fragmentos controle. Foram registrados 83 morcegos de 21 espécies. Este estudo traz indicações conservacionistas de que plantios de seringais funcionam melhor como refúgio e corredor de fauna para morcegos do que eucaliptos, que têm copas muito abertas. Além disso, ainda se pode inferir que o fogo experimental, realizado dois anos antes da amostragem, teve um impacto mediano na quiropterofauna, que se mostrou menos impactada que nas áreas de eucalipto. Por fim, recomenda-se que monoculturas de eucalipto ou seringais invistam em estratégias de manutenção de sub-bosque para serem mais atrativas para a fauna.