bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review of Virtual Week for Prospective Memory Assessment: Clinical Implications
Authors: Rendell Peter G. , Henry Julie D. 
Published: April 2009

AbstractIt is now recognised that prospective memory (PM) failures are commonly observed in clinical groups, and have important implications for functional independence. However, well-validated measures of PM have traditionally been lacking, making this construct difficult to assess in clinical practice. Rendell and Craik's (2000) Virtual Week measure was developed as an indicator of PM, and has been shown to have good psychometric properties and be sensitive to the effects of normal and abnormal adult ageing, as well as various forms of pathology. In this article, an overview of Virtual Week's characteristics is presented, and the literature relating to use of this measure in various populations reviewed. The potential implications of the development of a new computerised version of Virtual Week for clinical practice are discussed.
Memory for Intentions Screening Test: Psychometric Properties and Clinical Evidence
Authors: Raskin Sarah A. 
Published: April 2009

AbstractAs the field of prospective memory (ProM) research has expanded, recognition of the need to make a clinical diagnosis of ProM difficulties has also increased. In addition, there is increasing interest in understanding in more detail the ways in which ProM deficits differ in populations with different underlying neurological dysfunctions. While questionnaires, naturalistic studies and laboratory studies have all been invaluable in furthering our understanding of ProM, until recently there has not been a standardised clinical measure. The Memory for Intentions Screening Test (MIST) was designed to be a relatively brief clinical measure of ProM in clinical populations. The MIST allows for comparisons of performance with event-based and time-based cues. The MIST also has some items with a short (2-minute) and some with a long (15-minute) delay period. Finally, the MIST contains items that require a verbal response as well as items that require an action response. The MIST has now been used in studies of normal ageing as well as a range of clinical populations, including individuals with traumatic brain injury, individuals with HIV infection and individuals with schizophrenia. The psychometric properties of the MIST have been found to be acceptable. Data from each of the clinical populations that have been administered the MIST demonstrate good specificity and sensitivity of the measure as well as the ability to begin to make comparisons about different patterns of performance between disease types.
Time-Based Prospective Memory in Children With Autism Spectrum Disorder
Authors: Altgassen Mareike , Williams Tim I. , Bölte Sven , Kliegel Matthias 
Published: April 2009

AbstractIn this study, for the first time, prospective memory was investigated in 11 school-aged children with autism spectrum disorders and 11 matched neurotypical controls. A computerised time-based prospective memory task was embedded in a visuospatial working memory test and required participants to remember to respond to certain target times. Controls had significantly more correct prospective memory responses than the autism spectrum group. Moreover, controls checked the time more often and increased time-monitoring more steeply as the target times approached. These differences in time-checking may suggest that prospective memory in autism spectrum disorders is affected by reduced self-initiated processing as indicated by reduced task monitoring.
Between Dissonance and Dissidence: Socialist Modernism in the German Democratic Republic
Authors: Silverberg Laura 
Published: April 2009

Abstract
Both communist party officials and western observers have typically interpreted the composition of modernist music in the Eastern Bloc as an act of dissidence. Yet in the German Democratic Republic (GDR), the most consequential arguments in favor of modernism came from socialists and party members. Their advocacy of modernism challenged official socialist realist doctrine, but they shared with party bureaucrats the conviction that music ought to contribute to the development of socialist society. Such efforts to reform musical life from a Marxist-Leninist standpoint were typical of the first generation of East Germany's intelligentsia, who saw socialist rule as the only guarantee against the reemergence of German fascism. Two of East Germany's most prominent composers, Hanns Eisler and Paul Dessau, routinely used the twelve-tone method in works carrying an explicitly socialist text. During preparations for the 1964 Music Congress, aesthetician Günter Mayer drew from Eisler's Lenin Requiem and Dessau's Appell der Arbeiterklasse to argue that modernist techniques were highly appropriate for giving expression to contemporary social conditions. The efforts of these socialists to reconcile modernist techniques with their understanding of socialism undermine basic divisions between communism and capitalism, complicity and dissent, and socialist realism and western modernism.
The 1945 Stravinsky Debates: Nigg, Messiaen, and the Early Cold War in France
Authors: Sprout Leslie A. 
Published: April 2009

Abstract
In spring 1945, a small group of students, among them Serge Nigg and Pierre Boulez, protested during the first performances in liberated Paris of the neoclassical works Stravinsky had composed in America. Whereas Boulez's biographers have interpreted the student protests as a sign of René Leibowitz's successful promotion of serialism in France, scholars of the Cold War have seen the 1945 concerts as a precursor to Stravinsky's participation in the 1952 L'Œuvre du XXe siècle, a festival in Paris indirectly funded by the CIA. These interpretations subsume the immediate postwar period in France within a synchronic view of the early Cold War era. But the 1945 protests against Stravinsky were not about the decisive embrace of a single musical style; rather, they were about the desire of young French composers to play an active role in shaping the postwar future of music in France.
In 1945, Nigg—and not Boulez—represented the aesthetic opinions of a generation of French composers who had grown up during the German occupation of Paris and the political aspirations of those who, like Nigg, flocked to the French Communist Party at war's end. Nigg's participation in the 1945 Stravinsky debates gives us occasion to examine his earliest musical compositions and the political opinions he would express with increasing ideological fervor in the 1950s. Although in verbal pronouncements he supported socialist realism, Nigg's rare and complex use of a French folk tune in his 1954 Piano Concerto betrays his ambivalence about the Soviet demand for communist composers to reject "falsely cosmopolitan tendencies" in favor of their national cultural heritage. Having rejected in 1945 both Stravinsky's neoclassicism and French nationalism (the latter tainted by associations with Vichy during the occupation), Nigg had to choose in the early Cold War between his aesthetic and political loyalties.
Effects of aquatic exposure to the insecticide carbaryl and density on aquatic and terrestrial growth and survival in American toads
Authors: Distel Christopher A. , Boone Michelle D. 
Published: April 2009

Abstract
No single mechanism has been explicitly linked to explain global amphibian declines, but pesticides have been implicated as potential drivers. In mesocosm experiments, we tested the hypotheses that American toads (Bufo americanus) would respond differently to the insecticide carbaryl at low or high density (i.e., competition) and that postmetamorphic terrestrial growth and survival would differ with larval exposure to pesticides and competition. Carbaryl reduced survival to metamorphosis and increased time to metamorphosis in the aquatic phase, which could have a negative impact on fitness. However, carbaryl exposure increased the mass at metamorphosis of toads from high-density ponds, which may positively affect fitness. Pond periphyton showed a short-term increase in abundance after carbaryl exposure, but long-term periphyton abundance was lower than controls. No latent effects of carbaryl were seen on toad overwinter survival or mass at spring emergence in the terrestrial phase, suggesting that initial size differences at metamorphosis were overcome. Following individuals through multiple life stages is important because latent effects of exposure may not be predictable based on metamorphic endpoints alone.
(Pro)renin Receptor–Mediated Signal Transduction and Tissue Renin-Angiotensin System Contribute to Diabetes-Induced Retinal Inflammation
Authors: Satofuka Shingo , Ichihara Atsuhiro , Nagai Norihiro , Noda Kousuke , Ozawa Yoko , Fukamizu Akiyoshi , Tsubota Kazuo , Itoh Hiroshi , Oike Yuichi , Ishida Susumu 
Published: April 2009

OBJECTIVE
The term “receptor-associated prorenin system” (RAPS) refers to the pathogenic mechanisms whereby prorenin binding to its receptor dually activates the tissue renin-angiotensin system (RAS) and RAS-independent intracellular signaling via the receptor. The aim of the present study was to define the association of the RAPS with diabetes-induced retinal inflammation.

RESEARCH DESIGN AND METHODS
Long-Evans rats, C57BL/6 mice, and angiotensin II type 1 receptor (AT1-R)-deficient mice with streptozotocin-induced diabetes were treated with (pro)renin receptor blocker (PRRB). Retinal mRNA expression of prorenin and the (pro)renin receptor was examined by quantitative RT-PCR. Leukocyte adhesion to the retinal vasculature was evaluated with a concanavalin A lectin perfusion–labeling technique. Retinal protein levels of vascular endothelial growth factor (VEGF) and intercellular adhesion molecule (ICAM)-1 were examined by ELISA. Retinal extracellular signal–regulated kinase (ERK) activation was analyzed by Western blotting.

RESULTS
Induction of diabetes led to significant increase in retinal expression of prorenin but not the (pro)renin receptor. Retinal adherent leukocytes were significantly suppressed with PRRB. Administration of PRRB inhibited diabetes-induced retinal expression of VEGF and ICAM-1. To clarify the role of signal transduction via the (pro)renin receptor in the diabetic retina, we used AT1-R–deficient mice in which the RAS was deactivated. Retinal adherent leukocytes in AT1-R–deficient diabetic mice were significantly suppressed with PRRB. PRRB suppressed the activation of ERK and the production of VEGF, but not ICAM-1, in AT1-R–deficient diabetic mice.

CONCLUSIONS
These results indicate a significant contribution of the RAPS to the pathogenesis of diabetes-induced retinal inflammation, suggesting the possibility of the (pro)renin receptor as a novel molecular target for the treatment of diabetic retinopathy.
Hypoglycemia Unawareness Is Associated With Reduced Adherence to Therapeutic Decisions in Patients With Type 1 Diabetes
Authors: Smith Charlotte B. , Choudhary Pratik , Pernet Andrew , Hopkins David , Amiel Stephanie A. 
Published: April 2009

OBJECTIVE
Hypoglycemia unawareness increases severe hypoglycemia risk. Hypoglycemia avoidance restores awareness, but it is difficult to sustain. We compared adherence to treatment changes by awareness status.

RESEARCH DESIGN AND METHODS
Case notes of 90 type 1 diabetic patients were analyzed retrospectively, identifying awareness status and insulin regimens over four visits. The proportion of patients adhering to advice and percent advice taken were calculated.

RESULTS
A total of 31 patients with hypoglycemia awareness and 19 patients with hypoglycemia unawareness were identified, with insulin regimens available in 23 and 13, respectively. Patients with hypoglycemia unawareness were older (P = 0.001) and had longer diabetes duration (P = 0.002) and lower A1C (P = 0.007). More patients with hypoglycemia unawareness reported severe hypoglycemia (P = 0.002) and fewer were adherent (53.8 vs. 87.0%, P = 0.046), with lower adherence scores (42.5 ± 24.7 vs. 75.3 ± 27.5%, P = 0.001).

CONCLUSIONS
Reduced adherence to changes in insulin regimen in hypoglycemia unawareness is compatible with habituation to hypoglycemic stress. Therapies aimed at reversing repetitive harmful behaviors may be useful to restore hypoglycemia awareness and protection from severe hypoglycemia.
TRIB3 Functional Q84R Polymorphism Is a Risk Factor for Metabolic Syndrome and Carotid Atherosclerosis
Authors: Gong Hui-ping , Wang Zhi-hao , Jiang Hao , Fang Ning-ning , Li Ji-sheng , Shang Yuan-yuan , Zhang Yun , Zhong Ming , Zhang Wei 
Published: April 2009

OBJECTIVE
To determine the association of TRIB3 Q84R polymorphism with metabolic syndrome (MetS) and carotid atherosclerosis.

RESEARCH DESIGN AND METHODS
A case-control study enrolled 513 Chinese subjects in three groups: control, MetS, and obese. The functional TRIB3 Q84R polymorphism was genotyped among subjects undergoing carotid ultrasonography. The clinical and biochemical characteristics were determined.

RESULTS
For individuals with the TRIB3 R84 allele, the odds ratio for developing MetS was 2.349 (P = 0.018), abdominal obesity 2.351 (P = 0.012), hypertriglyceridemia 2.314 (P = 0.00003), and insulin resistance 1.697 (P = 0.023). Likewise, the odds ratio for individuals with the TRIB3 R84 allele to develop thickened intima-media thickness was 2.208 (P = 0.040).

CONCLUSIONS
Individuals with the functional TRIB3 Q84R polymorphism are at risk for MetS. The TRIB3 R84 allele especially predisposes to carotid atherosclerosis in part through the effects of abdominal obesity, hypertriglyceridemia, and insulin resistance.
Adiponectin and Lipoprotein Particle Size
Authors: Weiss Ram , Otvos James D. , Flyvbjerg Allan , Miserez Andre R. , Frystyk Jan , Sinnreich Ronit , Kark Jeremy D. 
Published: April 2009

OBJECTIVE
Adiponectin has been postulated to affect lipid and insulin signal transduction pathways. We evaluated the relationships of plasma adiponectin with lipoprotein mean particle size and subclass concentrations, independent of obesity and insulin sensitivity.

RESEARCH DESIGN AND METHODS
A cross-sectional analysis of 884 young Israeli adults who participated in the population-based Jerusalem Lipid Research Clinic (LRC) study was conducted. Lipoprotein particle size was assessed using proton nuclear magnetic resonance.

RESULTS
In multivariable linear regression models that included sex, BMI, waist circumference, homeostasis model assessment of insulin resistance, and leptin, adiponectin was associated with mean LDL size (standardized regression coefficient B = 0.20; P &lt; 0.001), VLDL size (B = −0.12; P &lt; 0.001), and HDL size (B = 0.06; P = 0.013). Adiponectin was inversely related to large VLDL (P &lt; 0.001) but positively to small VLDL (P = 0.02), inversely related to small LDL (P &lt; 0.006) but positively to large LDL (P &lt; 0.001), and positively related to large HDL (P &lt; 0.001) subclass concentrations.

CONCLUSIONS
Adiponectin is favorably associated with lipoprotein particle size and subclass distribution independent of adiposity and insulin sensitivity.
New isosporoid coccidian parasites of sayaca tanager, Thraupis sayaca, from South America
Authors: Berto Bruno , Balthazar Lianna , Flausino Walter , Lopes Carlos 
Published: April 2009

AbstractThree new coccidian (Apicomplexa, Eimeriidae) species from the sayaca tanager, Thraupis sayaca, from Brazil, are reported in the current study. Isospora sanhaci sp. nov. oocysts are spherical to subspherical, 22.1 × 21.0 μm, with smooth, bilayered wall, ∼1.0 μm. Micropyle, oocyst residuum and polar granule are absent, while Stieda and substieda bodies are present. Sporocysts are elongated, 17.0 × 9.9 μm. Sporocyst residuum is present, sporozoites have one refractile body and a nucleus. Isospora sayacae sp. nov. are spherical to subspherical, 28.9 × 27.4 μm, with smooth, bilayered wall, ∼1.3 μm. Micropyle, oocyst residuum and polar granule are absent, while Stieda and substieda bodies are present. Sporocysts are bottle-shaped, 23.4 × 11.8 μm and containing a sporocyst residuum and sporozoites with one refractile body and a nucleus. Isospora silvasouzai sp. nov. are spherical to subspherical, 25.5 × 22.6 μm, with a smooth, bilayered wall, ∼1.0 μm. Micropyle and oocyst residuum are absent, but one polar granule is present. Sporocysts are pyriform ellipsoidal, 17.6 × 10.5 μm. Stieda and substieda bodies and sporocyst residuum are present and sporozoites have one refractile body and a nucleus.
Ligophorus uruguayense sp. nov. (Monogenea, Ancyrocephalidae), a gill parasite from Mugil platanus (Mugiliformes, Mugilidae) in Uruguay
Authors: Siquier Gabriela , Núñez Margarita 
Published: April 2009

AbstractThe present study describes a new species, Ligophorus uruguayense, parasitizing the gills of Mugil platanus Günther, 1880 from the coast of Uruguay. It differs from all other species of the genus mainly in the shape of the ventral bar, the thick process at the distal end of the inner root of ventral anchors, the J-shaped penis accessory piece and the vaginal tube showing transverse annulations at its distal end, the host species, and geographical distribution. This is the first description of a species of Ligophorus from a mullet in the South Atlantic Ocean.
Parasite fauna of the mediterranean grenadier Coryphaenoides mediterraneus (Giglioli, 1893) from the Mid-Atlantic Ridge (MAR)
Authors: Kellermanns Esra , Klimpel Sven , Palm Harry 
Published: April 2009

AbstractA total of 38 Coryphaenoides mediterraneus from the Charlie-Gibbs Fracture Zone (CGFZ), a part of the Mid-Atlantic Ridge (MAR), was studied for parasites and feeding ecology. Sixteen different parasite species were found, most of them belonging to the Digenea (6 species) and Nematoda (6). Twelve new host and 11 new locality records were established, and 8 deep-sea generalists and 5 deep-sea specialists were found. Twelve adult and 3 larval parasites occurred, with Allopodocotyle margolisi (Digenea), Tetraphyllidea indet. (Scolex pleuronectis, Cestoda) and Ascarophis longiovata (Nematoda) being the predominant species. These parasites reached a prevalence of 50.0%, 86.8% and 68.4% with an intensity of infection of 1–10, 1–91 and 1–74, respectively. The food consisted of crustaceans and cephalopods; no further prey items such as fish could be identified. Coryphaenoides mediterraneus demonstrates a parasite fauna similar to that of other deep-sea macrourids. No MAR-specific parasite species were found, and the collected helminths are common fish parasites of the North Atlantic deep-sea basin and the adjacent continental shelf regions. Only few larval epipelagic generalists such as ascaridoid nematodes were found, due to the deep origin of the studied fish between 1700–3500 m. The recorded species rich parasite fauna reflects the wide depth range and opportunistic feeding behaviour of C. mediterraneus on benthopelagic food. The recorded parasite species composition around the MAR appears to be similar to other deep-sea locations in the Atlantic Ocean, demonstrating the wide zoogeographical distribution of these deep-sea metazoans. Consequences of the MAR, the CGFZ and the homogeneous deep-sea environmental conditions for the parasite species distribution are discussed.
A new species of Thelandros (Nematoda, Oxyuroidea, Pharyngodonidae) in Leiolepis reevesi (Sauria, Agamidae) from Vietnam
Authors: Dung Bui , Bursey Charles , Goldberg Stephen 
Published: April 2009

AbstractThelandros vietnamensis sp. nov. (Oxyuroidea, Pharyngodonidae) from the intestines of an agamid lizard, Leiolepis reevesi, collected in Vietnam is described and illustrated. Thelandros vietnamensis represents the 3rd Oriental species to be described and is distinguished from all other species by length of spicule (485–536 μm) of the male; all other species have spicules less than 200 μm.
Effects of niclosamide on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum: an enzyme-histochemical study
Authors: Wang Wei , Li Hongjun , Liang Yousheng , Dai Jianrong 
Published: April 2009

AbstractAn enzyme-histochemical study of five enzymes, namely succinate dehydrogenase (SDH), lactate dehydrogenase (LDH), cytochrome oxidase (CCO), cholinesterase (CHE) and nitric oxide synthase (NOS), was elucidated in the soft tissues of Oncomelania hupensis, the intermediate host snail of Schistosoma japonicum, before and after the treatment with a suspension concentrate of niclosamide (SCN). Following the treatment of SCN, a marked loss occurred in the activity of the five enzymes mentioned above. LDH and SDH showed their strongest activity in the buccal mass and muscular fibers, CCO in buccal mass and liver, CHE in pellicle and ganglia, and NOS in muscular fibers and pharyngeal canal. The results indicate that SCN impairs the activities of the enzymes influencing the transfer of neurotransmitter and energy supply in O. hupensis, ultimately leading to the loss of various physiological functions, which is considered to be a cause of death in O. hupensis.
Chewing lice from wild passerines (Aves, Passeriformes) from Vietnam, with description of a new species of the genus Brueelia (Phthiraptera, Ischnocera, Philopteridae)
Authors: Sychra Oldřich , Literák Ivan , Hung Nguyen , Podzemný Petr 
Published: April 2009

AbstractSeven species of chewing lice (Insecta: Phthiraptera) were found on six species of passerine birds (Passeriformes) in northern Vietnam. A description and illustrations of Brueelia alophoixi sp. nov. ex Alophoixus pallidus (Pycnonotidae) are given. New host records are: Abroscopus superciliaris (Sylviidae) for Myrsidea sp.; and Orthotomus sutorius (Sylviidae) and Lonchura striata (Estrildidae) for Brueelia spp.
Anti-Pentatrichomonas hominis activity of newly synthesized benzimidazole derivatives — in vitro studies
Authors: Chomicz Lidia , Padzik Marcin , Laudy Agnieszka , Kozłowska Mariola , Pietruczuk Anna , Piekarczyk Janusz , Godineau Nadine , Olędzka Gabriela , Kazimierczuk Zygmunt 
Published: April 2009

AbstractPentatrichomonas hominis, a parasitic protozoan often detected in human diarrheic stools, is the cause of severe morbidity in newborns and children, particularly in tropical zones. The flagellate is resistant to many disinfectants and anti-protozoan drugs. Therefore in this study we have synthesized three novel 4,5,6,7-tetrabromobenzimidazole (TBBI) derivatives carrying a polyfluoroalkyl substituent in position 2 of the benzimidazole scaffold, namely 2-trifluoromethyl-TBBI (CF3-TBBI), 2-nonafluorobutyl-TBBI (C4F9-TBBI), and 2-nonadecafluorononyl-TBBI (C9F19-TBBI), that next we tested for their in vitro activity against P. hominis.Widely applied anti-protozoal drug, metronidazole as a reference was used. All the investigated agents were added to 24 h P. hominis cultures; each of them was administered at three different concentrations. Number of the moving trichomonads was determined and compared with the control cultures. Different anti-trichomonal activity occurred depending on a kind of compound and its concentration. C4F9-TBBI was the most effective TBBI derivative tested: the agent, at the highest concentration 24.2 μg/ml, after 72 h reduced the number of viable trichomonads to 44.3%; C9F19-TBBI, at the concentration 24 μg/ml reduced the number of the flagellates to 58.5%. Paradoxically, metronidazole after the same time given at the highest concentration increased trophozoite counts by 464.6% in comparison with the control cultures (100%).