bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface‐Level Muscle Deformation as a Correlate for Joint Torque
Authors: Alvarez Jonathan T. , de Marcillac Ariane , Jin Yichu , Gerez Lucas F. , Araromi Oluwaseun A. , Walsh Conor J. 
Published: May 2024

AbstractWearable technology excels in estimating kinematic and physiological data, but estimating biological torques remains an open challenge. Deformation of the skin above contracting muscles—surface‐level muscle deformation—has emerged as a promising signal for joint torque estimation. However, a lack of ground‐truth measures of surface‐level muscle deformation has complicated the evaluation of wearable sensors designed to measure surface‐level muscle deformation. A non‐contact methodology is proposed for ground‐truth measurement of surface‐level muscle deformation using a 2D laser profilometer. It shows how three metrics of surface‐level muscle deformation—peak radial displacement:r =0.94 ± 0.05, surface curvature:r=0.78 ± 0.10, surface strain:r =0.83 ± 0.12—correlate strongly to changes in volitional elbow torque, further exploring the impact of measurement location or joint angle on these relationships. A nonlinear, lead‐lag relationship between surface‐level muscle deformation and torque is also found. The findings suggest that surface‐level muscle deformation is a promising signal for non‐invasive, real‐time estimates of torque. By standardizing measurement, the methodology can help inform the design of future wearable sensors.
First Order Methods for Geometric Optimization of Crystals: Theoretical Derivations
Authors: Tsili Antonia , Dyer Matthew S. , Gusev Vladimir V. , Krysta Piotr , Savani Rahul 
Published: May 2024

AbstractCrystal structures are important formations, bases of materials used in everyday life. A lot of effort is dedicated to the creation of new materials, starting from the study and combination of crystal structures' properties[1] through the crystals' geometric optimization. In the meantime, an equal amount of effort is dedicated to the study and development of methods employed in optimization problems; this, nevertheless, is carried out independently, in the context of computer science. There is a need, therefore, to acknowledge and highlight the overlap between the two fields, whilst creating a common language and establishing the theoretical foundations on which the optimization methods can become physically interpreted in the case of crystals. This article provides a detailed introduction to the theory behind the geometric optimization of crystals from the point of view of computer science, so as to facilitate interdisciplinary cooperation. Its target is to familiarize scientists from different fields with the problem, its parameters, and their derivations, in order to motivate their assistance in the creation, implementation, and application of new methods for the geometric optimization of crystal structures.
Androgens Modulate the Immune Profile in a Mouse Model of Polycystic Ovary Syndrome
Authors: Torstensson Sara , Ascani Angelo , Risal Sanjiv , Lu Haojiang , Zhao Allan , Espinosa Alexander , Lindgren Eva , Johansson Maria H. , Eriksson Gustaw , Barakat Maya , Karlsson Mikael C.I. , Svensson Camilla , Benrick Anna , Stener‐Victorin Elisabet 
Published: May 2024

AbstractPolycystic ovary syndrome (PCOS) is associated with a low‐grade inflammation, but it is unknown how hyperandrogenism, the hallmark of PCOS, affects the immune system. Using a PCOS‐like mouse model, it is demonstrated that hyperandrogenism affects immune cell populations in reproductive, metabolic, and immunological tissues differently in a site‐specific manner. Co‐treatment with an androgen receptor antagonist prevents most of these alterations, demonstrating that these effects are mediated through androgen receptor activation. Dihydrotestosterone (DHT)‐exposed mice displayed a drastically reduced eosinophil population in the uterus and visceral adipose tissue (VAT). A higher frequency of natural killer (NK) cells and elevated levels of IFN‐γ and TNF‐α are seen in uteri of androgen‐exposed mice, while NK cells in VAT and spleen displayed a higher expression level of CD69, a marker of activation or tissue residency. Distinct alterations of macrophages in the uterus, ovaries, and VAT are also found in DHT‐exposed mice and can potentially be linked to PCOS‐like traits of the model. Indeed, androgen‐exposed mice are insulin‐resistant, albeit unaltered fat mass. Collectively, it is demonstrated that hyperandrogenism causes tissue‐specific alterations of immune cells in reproductive organs and VAT, which can have considerable implications on tissue function and contribute to the reduced fertility and metabolic comorbidities associated with PCOS.
Fully Floatable Mortise‐and‐Tenon Architecture for Synergistically Photo/Sono‐Driven Evaporation Desalination and Plastic‐Enabled Value‐Added Co‐Conversion of H2O and CO2
Authors: Li Yingying , Yao Tongrong , Wang Yanqiu , Chen Jiahui , You Haining , Lu Jing , Xiong Yi , Xiong Zhongduo , Liu Jia , Qi Yajuan , Wang Wenwen , Wang Dong 
Published: May 2024

AbstractEstablishing an advanced ecosystem incorporating freshwater harvesting, plastic utilization, and clean fuel acquisition is profoundly significant. However, low‐efficiency evaporation, single energy utilization, and catalyst leakage severely hinder sustainable development. Herein, a nanofiber‐based mortise‐and‐tenon structural Janus aerogel (MTSJA) is strategically designed in the first attempt and supports Z‐scheme catalysts. By harnessing of the upper hydrophilic layer with hydrophilic channels embedding into the hydrophobic bottom layer to achieve tailoring bottom wettability states. MTSJA is capable of a fully‐floating function for lower heat loss, water supply, and high‐efficiency solar‐to‐vapor conversion. Benefiting from the ultrasonic cavitation effect and high sensitivity of materials to mechanical forces, this is also the first demonstration of synergistic solar and ultrasound fields to power simultaneous evaporation desalination and waste plastics as reusable substrates generating fuel energy. The system enables persistent desalination with an exceptional evaporation rate of 3.1 kg m−2 h−1 and 82.3% efficiency (21 wt.% NaCl solution and 1 sun), and realizes H2, CO, and CH4 yields with 16.1, 9.5, and 3 µmol h−1 g−1, respectively. This strategy holds great potential for desalination and plastics value‐added transformation toward clean energy and carbon neutrality.
Bidirectional Rotating Turbine Hybrid Triboelectric‐Electromagnetic Wave Energy Harvester for Marine Environment Monitoring
Authors: Li Tianyu , Wang Xiao , Wang KuanKuan , Liu Yixin , Li Chenxi , Zhao Fuhai , Yao Yongming , Cheng Tinghai 
Published: May 2024

AbstractHydrokinetic energy, a vital renewable resource, holds promise for addressing fossil fuel shortages to ensure a sustainable future. This study proposes an efficient and stable ocean wave energy harvesting system that combines a triboelectric nanogenerator (TENG), an electromagnetic generator (EMG) with a planetary gear system, and a driving turbine. The turbine transforms the up‐and‐down motion in water into continuous, unidirectional rotational motion. An EMG device accelerated by a planetary gear system further ensures sustained output at very low frequencies (0.25 Hz) and boosts the upper limit of power generation at medium to high frequencies. Under water wave conditions with a 1 Hz frequency, the TENG component yields an output of up to 2200 V and 122 µA, while the average EMG output is 15 V and 80 mA. Remarkably, the entire system maintains a steady and uninterrupted output even at extremely low frequencies (0.25 Hz). The peak power outputs for the TENG and EMG components are 115 and 350 mW, respectively, with power densities of 32.55 and 329.78 W m−3, surpassing prior achievements. This research demonstrates self‐powered applications and provides an efficient method to amplify water wave forces, enhancing energy harvesting capabilities for practical marine environmental monitoring.
Electrocatalysts with Highly Dispersed Cerium in Nickel Matrix for Hydrogen Evolution in Alkaline Electrolyte
Authors: Wang Aoqi , Long Guifa , Chen Jun , An Xiurui , Yao Tingting , Li Can 
Published: May 2024

AbstractIt is challenging to develop highly active and durable electrocatalysts for hydrogen evolution reaction (HER) in alkaline water electrolysis. Herein, an electrocatalyst is synthesized with highly dispersed cerium in a nickel matrix, showing an overpotential of 169 mV for HER at a current density of 500 mA cm−2, about 137 mV lower than that observed without cerium. Kinetic analysis results suggest that doping cerium facilitates the evolution of intermediate H for HER, thus accelerating the process of water dissociation. Density functional theory (DFT) calculations also indicate that the introduction of highly dispersed cerium can lower the energy barrier of the kinetically sluggish Volmer step by altering the orbital occupation near the Fermi level, promoting the process of water dissociation. Furthermore, the electrolyzer constructed with the electrocatalyst exhibits a cell voltage as low as 1.67 V at 800 mA cm−2 for 2000 h in 7 м KOH at 80 °C. The robust property makes it an excellent candidate electrocatalyst for practical applications.
Phosphorus Defect Mediated Electron Redistribution to Boost Anion Exchange Membrane‐Based Alkaline Seawater Electrolysis
Authors: Guo Lili , Chi Jingqi , Cui Tong , Zhu Jiawei , Xia Yanan , Guo Hailing , Lai Jianping , Wang Lei 
Published: May 2024

AbstractIt is of essential importance to design bifunctional electrocatalysts with excellent performance for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) in seawater splitting. Herein, an approach for manipulating electron redistribution in NiCoP treated by P defect (Pv) engineering (NiCoPv@NF) is presented, exhibiting excellent catalytic activities and stability toward HER/OER in alkaline seawater solution. The Pv reduces the surface electrooxidation reconfiguration energy barrier, making it easier to drive the local conversion of crystals to active oxy(hydroxide) in OER. In addition, the Ni site of NiCoPv and the Co site of NiCoOOH are the active sites for HER and OER processes, respectively. In situ generated PO43− adsorbed on the catalyst surface causes spatial repulsion, preventing Cl− corrosion in seawater electrolysis. The seawater AEM electrolyzer using NiCoPv@NF couple achieves excellent performance of high activity (2.43 V at 500 mA cm−2) and long‐term durability (500 mA cm−2 over 110 h). The working efficiency of AEM in 1.0 M KOH is as high as 77.0% at 100 mA cm−2 with the price of per GGE H2 as low as $ 0.87.
Modulating Molecular Interaction of Zwitterion Toward Rational Interface Engineering of Perovskite Solar Cells
Authors: Kim Hangyeol , Choi Kyoungwon , Yoon Geon Woo , Kim Dohyun , Lee Dae Hwan , Choi Yelim , Jung Hyun Suk , Song Seulki , Park Taiho 
Published: May 2024

AbstractPassivation of perovskite crystals is a crucial strategy to improve the efficiency and stability of perovskite solar cells (PSCs). Zwitterions, which contain both positive and negative charges in the molecule, can be used to passivate perovskite crystals. However, these materials strongly interact with each other, resulting in extremely low solubility in common organic solvents. The low solubility of zwitterions hinders the formation of uniform films, which negatively affects perovskite crystal growth. In this study, a liquid‐type zwitterion (LTZ) is synthesized by modulating intermolecular interactions of the zwitterion (3‐(1‐Pyridinio)‐1‐propanesulfonate). By suppressing intermolecular interactions, the solubility and processibility of the zwitterion in common organic solvents are successfully improved. The well‐distributed LTZ‐treated films are obtained, resulting in better electrical properties for the PSCs compared to solid‐type zwitterion‐based devices. With these characteristics, the resulting device achieves a power conversion efficiency of 24.9% with excellent thermal stability (under 60 °C and N2 atmosphere), maintaining over 80% of its initial efficiency for 1968 h. In addition, the PSC module (active area of 32.7 cm2) achieves an improved efficiency of 19.86% with high open‐circuit voltage and fill factor. The results suggest that interface engineering with an LTZ has the potential to fabricate efficient and stable PSCs.
Reconfiguring the Electrolyte Network Structure with Bio‐Inspired Cryoprotective Additive for Low‐Temperature Aqueous Zinc Batteries
Authors: Hu Bin , Chen Tao , Wang Yinan , Qian Xiaohu , Zhang Qianjin , Fu Jiajun 
Published: May 2024

AbstractDespite promising performance at ambient temperature, the development of aqueous zinc batteries is jeopardized by the freeze of aqueous electrolytes and deteriorative electrode‐electrolyte interphase at low temperatures. Herein, inspired by the cryoprotective mechanism of extracellular polysaccharides in biological organisms, a quaternized galactomannan polysaccharide (q‐GPA) is proposed as a cryoprotective additive for improving low‐temperature performance of aqueous zinc batteries. Mechanistic studies revealed that a multi‐hydroxyl galactomannan backbone can substantially attenuate the activity of water molecules through the reconfiguration of the hydrogen bond network, which inhibits ice crystal formation at subzero temperatures and thus depress the freezing point of the electrolyte. Meanwhile, the quaternary ammonium groups tethered on the q‐GPA skeleton are intended to neutralize the interfacial electric field through electrostatic repulsion, thereby accelerating Zn2+ deposition kinetics and prohibiting zinc dendrite growth. Impressively, the q‐GPA–modified electrolyte enables an extended lifespan of over 1700 h in Zn||Zn symmetric battery at a high current density of 3 mA cm−2 and an ultralong cycle life of 5000 cycles with a capacity retention of 99.2% in the Zn||Na2V6O16·1.5H2O (NVO) full battery at −30 °C. This work provides unprecedented possibilities for optimizing the electrolyte formulation of low‐temperature aqueous batteries.
The MIDAS touch: Frameworks for procedural model innovation and validation
Authors: Stapleton Stephanie N. , Cassara Michael , Roth Benjamin , Matulis Christina , Desmond Clare , Wong Ambrose H. , Cardell Annemarie , Moadel Tiffany , Lei Charles , Munzer Brendan W. , Moss Hillary , Nadir Nur Ain 
Published: May 2024

AbstractBackgroundSimulation‐based procedural practice is crucial to emergency medicine skills training and maintenance. However, many commercial procedural models are either nonexistent or lacking in key elements. Simulationists often create their own novel models with minimal framework for designing, building, and validation. We propose two interlinked frameworks with the goal to systematically build and validate models for the desired educational outcomes.MethodsSimulation Academy Research Committee and members with novel model development expertise assembled as the MIDAS (Model Innovation, Development and Assessment for Simulation) working group. This working group focused on improving novel model creation and validation beginning with a preconference workshop at 2023 Society for Academic Emergency Medicine Annual Meeting. The MIDAS group sought to (1) assess the current state of novel model validation and (2) develop frameworks for the broader simulation community to create, improve, and validate procedural models.FindingsWorkshop participants completed 17 surveys for a response rate of 100%. Many simulationists have created models but few have validated them. The most common barriers to validation were lack of standardized guidelines and familiarity with the validation process.We have combined principles from education and engineering fields into two interlinked frameworks. The first is centered on steps involved with model creation and refinement. The second is a framework for novel model validation processes.ImplicationsThese frameworks emphasize development of models through a deliberate, form‐follows‐function methodology, aimed at ensuring training quality through novel models. Following a blueprint of how to create, test, and improve models can save innovators time and energy, which in turn can yield greater and more plentiful innovation at lower time and financial cost. This guideline allows for more standardized approaches to model creation, thus improving future scholarship on novel models.
Precision medicine within health professions education: Defining a research agenda for emergency medicine using a foresight and strategy technique (FaST) review
Authors: Chan Teresa M. , Thoma Brent , Finnell John T. , Gordon Bradley D. , Farrell Susan , Pusic Martin , Cabrera Daniel , Gisondi Michael A. , Caretta‐Weyer Holly A. , Stave Christopher , Ankel Felix 
Published: May 2024

AbstractBackgroundPrecision medicine, sometimes referred to as personalized medicine, is rapidly changing the possibilities for how people will engage health care in the near future. As technology to support precision medicine exponentially develops, there is an urgent need to proactively improve our understanding of precision medicine and pose important research questions (RQs) related to its inclusion in the education and training of future emergency physicians.MethodsA seven‐step process was employed to develop a research agenda exploring the intersection of precision and emergency medicine education/training. A literature search of articles about precision medicine was conducted first, which informed the creation of future four scenarios in which trainees and practicing physicians regularly discuss and incorporate precision medicine tools into their discussions and work. Based on these futurist narratives, potential education RQs were generated by an expert panel. A total of 59 initial questions were subsequently categorized and refined to a priority list through a nominal group voting method. The top/priority questions were presented at the 2023 SAEM Consensus Conference on Precision Medicine, Austin, Texas, for further input.ResultsEight high‐value education RQs were developed, reflecting a holistic view of the challenges and opportunities for precision medicine education in the knowledge, skills, and attitudes relevant to emergency medicine. These questions contend with topics such as most effective pedagogical methods; intended resulting outcomes and behaviors; the generational differences between practicing emergency physicians, educators, and future trainees; and the desires and expectations of patients.ConclusionsEmergency medicine and emergency physicians must be prepared to understand precision medicine and incorporate this information into their “toolbox” of thinking, problem solving, and communication with patients and colleagues. This research agenda on how best to educate future emergency physicians in the use of personalized data to provide optimal health care is the focus of this article.
Beyond subsistence? The role of rural cooperatives in driving smallholder commercialization in Ethiopia
Authors: Geffersa Abebayehu Girma , Islam Md. Monirul 
Published: May 2024

AbstractThe transition from subsistence to market‐oriented agriculture holds the potential to boost rural economic progress and improve the well‐being of the rural poor in developing countries. Despite this potential, there is limited understanding of the key drivers for smallholder commercialization. In this study, we utilize comprehensive three‐wave panel data collected from three major maize‐producing regions in Ethiopia to examine the role of agricultural cooperatives in promoting smallholder commercialization. Employing a double‐hurdle model, we model smallholder commercialization as a two‐step decision process involving market participation and the extent of participation (sales quantity), conditional on market participation. Unobserved heterogeneity is accounted for using a correlated random effect procedure, and the potential endogeneity of cooperative membership is addressed through a control function approach. The findings reveal that cooperative membership increases the probability of market participation and the intensity of sales. However, further analysis demonstrates a heterogeneous relationship between cooperative membership and commercialization, underscoring the importance of targeted interventions to boost the contribution of cooperatives to rural development through commercialization. The main findings highlight that promoting smallholder commercialization through farmer groups necessitates implementing policies to increase cooperative membership, coupled with allocating resources that enhance the contribution of agricultural cooperatives [EconLit Citations: Q12, Q13, Q18].
Parallel patterns of genetic diversity and structure in circumboreal species of the Sphagnum capillifolium complex
Authors: Imwattana Karn , Aguero Blanka , Nieto‐Lugilde Marta , Duffy Aaron , Jaramillo‐Chico Juan , Hassel Kristian , Afonina Olga , Lamkowski Paul , Jonathan Shaw A. 
Published: May 2024

AbstractPremiseShared geographical patterns of population genetic variation among related species is a powerful means to identify the historical events that drive diversification. The Sphagnum capillifolium complex is a group of closely related peat mosses within the Sphagnum subgenus Acutifolia and contains several circumboreal species whose ranges encompass both glaciated and unglaciated regions across the northern hemisphere. In this paper, we (1) inferred the phylogeny of subg. Acutifolia and (2) investigated patterns of population structure and genetic diversity among five circumboreal species within the S. capillifolium complex.MethodsWe generated RAD sequencing data from most species of the subg. Acutifolia and samples from across the distribution ranges of circumboreal species within the S. capillifolium complex.ResultsWe resolved at least 14 phylogenetic clusters within the S. capillifolium complex. Five circumboreal species show some common patterns: One population system comprises plants in eastern North America and Europe, and another comprises plants in the Pacific Northwest or around the Beringian and Arctic regions. Alaska appears to be a hotspot for genetic admixture, genetic diversity, and sometimes endemic subclades.ConclusionsOur results support the hypothesis that populations of five circumboreal species within the S. capillifolium complex survived in multiple refugia during the last glacial maximum. Long‐distance dispersal out of refugia, population bottlenecks, and possible adaptations to conditions unique to each refugium could have contributed to current geographic patterns. These results indicate the important role of historical events in shaping the complex population structure of plants with broad distribution ranges.
Plasmablastic lymphoma: 2024 update on diagnosis, risk stratification, and management
Authors: Ramirez‐Gamero Andres , Martínez‐Cordero Humberto , Beltrán Brady E. , Florindez Jorge , Malpica Luis , Castillo Jorge J. 
Published: May 2024

AbstractDisease OverviewPlasmablastic lymphoma (PBL) is a rare CD20‐negative aggressive lymphoma with a poor prognosis under standard treatment options. Though PBL is associated with human immunodeficiency virus infection and other immunosuppressed states, it can also affect immunocompetent individuals.DiagnosisThe diagnosis requires a high clinical suspicion and pathological confirmation. EBER expression and MYC gene rearrangements are frequently detected. The differential diagnosis includes EBV+ diffuse large B‐cell lymphoma, extracavitary primary effusion lymphoma, ALK+ DLBCL, and HHV8+ large B‐cell lymphoma, among others.Risk StratificationAge ≥60 years, advanced clinical stage, and high intermediate and high International Prognostic Index scores are associated with worse survival.ManagementCombination chemotherapy regimens, such as EPOCH, are recommended. The addition of bortezomib, lenalidomide, or daratumumab might improve outcomes. Including PBL patients and their participation in prospective clinical trials is warranted.