bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: 5‐Fluoro‐1‐ (3,4‐dideoxy‐3‐fluoro‐6‐O‐trityl‐beta‐D‐glycerohex‐3‐eno‐pyranos‐2‐ulosy l) Uracil: Anticancer Agent
Authors: Ollapally Abraham P. , Bennouna‐Dorange Ismet , Whitaker Jr. Thomas L. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Some Fully 3′‐ and 4′‐C‐Branched‐Chain Sugar Nucleoside Analogues
Authors: Ton‐That T. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Biological Evaluation of 1,2‐Disubstituted Carbonucleosides of 6‐Substituted Purine and 8‐Azapurine
Authors: Santana L. , Teijeira M. , Uriarte E. , Teran C. , Andrei G. , Snoeck R. , Balzarini J. , De Clercq E. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel C‐5‐Substituted d4T Analogues Bearing Linker Arms as Potential Anti‐HIV Agents
Authors: Laduree D. , Fossey C. , Renoud‐Grappin M. , Fontaine G. , Camara F. , Gavriliu D. , Ciurea A. , Aubertin A. M. , Kirn A. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Antitumor Activity of 7‐O‐[2,6‐Dideoxy‐2‐fluoro‐5‐C‐ (trifluoromethyl)‐α‐L‐talopyranosyl]‐daunomycinone and ‐adriamycinone.
Authors: Nakai Ken , Takagi Yasushi , Tsuchiya Tsutomu 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: AS‐924, a Novel Bifunctional Prodrug of Ceftizoxime.
Authors: Kasai Masayasu , Hatano Satoru , Kitagawa Meiko , Yoshimi Akihisa , Shirahase Hiroaki , Nishimura Ken‐Ichi , Kakeya Nobuharu 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Members of the Macrosphelides from Microsphaeropsis sp. FO‐5050. Part 4.
Authors: Fukami Akiko , Taniguchi Yosuke , Nakamura Tomonori , Rho Mun‐Chual , Kawaguchi Kanako , Hayashi Masahiko , Komiyama Kanki , Omura Satoshi 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Attempts Towards Polymer‐Bond ′Push‐Pull′ Acetylenes.
Authors: Wilhelm Patrick , Neuenschwander Markus 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Antibacterial, Antifungal, and Anti‐HIV Evaluation of Norfloxacin Mannich Bases.
Authors: Pandeya S. N. , Sriram D. , Nath G. , De Clercq E. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Biological Activity of β‐Fluoroalkyl β‐Amino Alcohols
Authors: Bravo Pierfrancesco , Crucianelli Marcello , Ono Taizo , Zanda Matteo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mannich Bases as Model Compounds for Intramolecular Hydrogen Bonding. Part 2. Structure and Properties in Solution
Authors: Koll Aleksander , Wolschann Peter 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Studies of Gurmarin, a Sweetness‐Suppressing Polypeptide
Authors: Ota Masafumi , Shimizu Yasutake , Tonosaki Keiichi , Ariyoshi Yasuo 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitric Oxide: A Unique Endogenous Signaling Molecule in Vascular Biology (Nobel Lecture)
Authors: Ignarro Louis J. 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Determination of Quadrupolar and Dipolar NMR Correlation Times from Spin—Lattice and Spin—Spin Relaxation Rates
Authors: Carper W. Robert 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Spin—Spin Couplings
Authors: Kamienska‐Trela Krystyna , Wojcik Jacek 
Published: June 2010

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optimization for the Production of Ammonia from Urea in a Semi‐batch Reactor for Safe Feedstock in Power Plants: Experimental and Statistical Studies
Authors: Sahu Jaya N. , Meikap Bhim C. , Patwardhan Anand V. 
Published: June 2010

AbstractUrea hydrolysis for production of ammonia, in different application areas require safe use of ammonia, for removal of the NOx contaminates contained in a flue gas stream and increase in the efficiency of an electrostatic precipitator for the removal of fly ash from the flue gas stream. The single and combined effects of operating parameters such as initial feed concentrations, temperatures, reaction times, and stirring speeds on the production of ammonia from urea were analyzed using response surface methodology (RSM). Analysis of variance (ANOVA) showed a high coefficient of determination value (R2 = 0.967) and satisfactory prediction second order regression model was derived. The optimum production conditions determined for semi‐batch reactor were temperature 178°C, initial feed concentration 22.24 wt% of urea, time of reaction 43.2 min and stirring speed 1045 rpm. At optimum conversion conditions, the conversion of urea for production of ammonia was found to be ≥13%.
Self‐similar characteristics of network intrusion attempts and the implications for predictability
Authors: Wahid Alif , Leckie Christopher , Zhou Chenfeng 
Published: June 2010

AbstractOne way of proactively detecting multistage attacks such as Distributed Denial of Service (DDoS), worms and coordinated spamming is to profile hosts that engage in scanning activity and predict their future actions, which is a difficult challenge. We attempt to better understand this challenge by hypothesising that network intrusion attempts exhibit self‐similar characteristics. We analyse logs from the DShield repository of globally distributed IDS alerts corresponding to the first 2 weeks of January 2005 and present three pieces of evidence in favour of this hypothesis. First, we observed that the persistence of hosts that attempt network intrusions obey a power‐law relationship such that the overwhelming majority of hosts are short‐lived whereas a small number are highly persistent. Second, the distribution of hosts in the IP address space is broadly identical regardless of different categories of lifetimes and intrusion attempts. Finally, there is a scale invariant diurnal cycle with long‐range dependence in the number of unique hosts observed per unit time. The overall implication of these findings is that any predictive model must account for identical statistical characteristics regardless of the volumetric, spatiotemporal and categorical resolution of the observations used to build and train that model. Copyright © 2010 John Wiley & Sons, Ltd.
Crystal structures and isotope effect on Na5H3(SeO4)4·2H2O and Na5D3(SeO4)4·2D2O crystals
Authors: Fukami T. , Miyazaki J. , Tomimura T. , Chen R. H. 
Published: June 2010

AbstractDifferential scanning calorimetry (DSC) and X‐ray diffraction measurements have been performed on pentasodium trihydrogen tetraselenate dihydrate Na5H3(SeO4)4·2H2O and deuterated Na5D3(SeO4)4·2D2O crystals. Any distinct anomaly around 428 K in the DSC curves for both crystals is suggested to be caused by a chemical reaction of thermal decomposition with hydrolysis at high temperature. The space group symmetry (triclinic P$ \bar 1 $) and the structure parameters are determined at room temperature. The hydrogen atom in the centrosymmetric O‐H(D)‐O hydrogen bond of both crystals is found to be equally distributed at two equivalent sites in the bond. The expansions of two O‐H‐O hydrogen bonds by the substitution of deuterium are observed to be 0.016(6) and 0.011(4) Å. The geometric isotope effect on hydrogen bonds is confirmed to be existed in Na5H3(SeO4)4·2H2O. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Analysis of quantum dot fluorescence stability in primary blood mononuclear cells
Authors: Summers Huw D. , Holton Mark D. , Rees Paul , Williams Paul M. , Thornton Catherine A. 
Published: June 2010

AbstractA quantitative assessment of fluorescence signal generation and persistence in blood cells, measured at multiple points over a time course, is presented. Quantum dots (QDs) are inorganic fluorophores that are photostable and nonmetabolized and so can provide quantitative measures of cell biology over multiple cell generations. However, if the potential of these nanoparticles for long‐term reporting is to be realized, an understanding of the stability of their fluorescence in living cells is essential. CdTe/ZnS and CdSe/ZnS core/shell dots with peak emission wavelengths of 705 nm and 585 nm, respectively, were loaded, via endocytosis into mononuclear cells extracted from primary blood and flow cytometry used to measure the average fluorescence intensity per cell within populations >104. Time‐based study showed a saturation‐limited uptake of QDs with a characteristic time of 20 min and a maximum fluorescence signal that is linearly proportional to dot solution concentration. The fluorescence signal decreases after attachment and internalization within cells and is accurately described by a biexponential decay with a rapid initial decay followed by a much slower signal loss with characteristic times of 435 and 7,000 min respectively. Comparison with control samples indicates that interaction with the culture media is a major contributory factor to the initial signal decay. These results provide phenomenological descriptions of the evolving QD fluorescence within live cells with associated analytical equations that allow quantitative assessment of QD‐based assays. © 2010 International Society for Advancement of Cytometry
Superposition coding cooperative relaying communications: Outage performance analysis
Authors: Jia Xiangdong , Fu Haiyang , Yang Longxiang , Zhao Laiqiang 
Published: June 2010

AbstractUser cooperative is a powerful tool to combat fading and to increase robustness for communications over wireless channels. For cooperative relaying communications, the outage probability and the expected rate (throughput) can be greatly improved when the superposition coding relaying (SC‐relaying) strategy is employed. Under the assumption of high signal‐to‐noise ratio (SNR), this work contributes to a comprehensive investigation on the outage probability and the throughput of cooperative relaying communications system with only two‐level rate SC. Through strict mathematical process and deduction, the approximated close‐form expressions of the outage probabilities and the throughput of system are obtained for the first time. Based on the results, the impact of power and channel allocation fractions on system performance is carried out. With the aim of maximal throughput, a set of optimal solutions of system parameters are obtained by employing difference evolution arithmetic. The comparative numerical analyses show that the approximation results are feasible and correct. Copyright © 2010 John Wiley & Sons, Ltd.
Dialysis clinician bias regarding patient non‐compliance
Authors: Iacono Steven A. 
Published: June 2010

AbstractBACKGROUNDMost of the research regarding dialysis patient non‐compliance with the treatment regimen has not taken clinician views and biases into consideration. Studies in other medical ﬁelds have noted that an innate bias among professionals often leads to differences in treatment provision.METHODSThis study assessed the views of 135 dialysis social workers, dietitians, and nurses with regard to which types of patients they believe are likely to be non‐compliant and why patients engage in these behaviors. An analysis of responses sought to identify any patterns of bias.RESULTSThe majority of clinicians identiﬁed patient‐centered factors as being the primary cause of non‐compli‐ance. Commonly noted beliefs were that patients are unable to understand the importance of compliance or they are simply in denial of their illness. Demographic variables such as patient education level, income level, and the presence of obesity were all found to inﬂuence how clinicians view patients and their behaviors.DISCUSSIONDialysis social workers, dietitians, and nurses in this study rarely identiﬁed their personal views or clinic factors as being causative agents in patient non‐compliance. Wide differences between the views of the 3 studied professions highlights the subjective nature of labeling patients as being compliant or non‐compliant.
Serum and glucocorticoid‐inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis
Authors: Catela Catarina , Kratsios Paschalis , Hede Marianne , Lang Florian , Rosenthal Nadia 
Published: June 2010

AbstractThe unquestionable importance of the cardiovascular system for pre‐ and postnatal life has prompted dissection of the molecular mechanisms underlying its development. Serum and glucocorticoid‐inducible kinase 1 (SGK1) is a serine/threonine kinase lying downstream of the phosphoinositide 3 (PI3) kinase pathway, whose embryonic function remains unknown. Here, we show that disruption of Sgk1 in the mouse C57BL/6J genetic background leads to embryonic lethality at embryonic day 10.5–11.5 due to severe embryonic and extraembryonic angiogenic defects and to impaired myocardial trabeculation. Absence of SGK1 results in increased apoptosis of endothelial cells, and of vascular smooth muscle cells highlighting a prosurvival role for SGK1 during angiogenesis. Sgk1 null embryos also display reduced expression levels of Notch signaling genes and decreased expression of the arterial markers Efnb2 and Nrp1. These findings uncover a novel and essential function for SGK1 in cardiovascular development contributing to a better understanding of mammalian angiogenesis. Developmental Dynamics 239:2149–2160, 2010. © 2010 Wiley‐Liss, Inc.
Ttyh1, a Ca2+‐binding protein localized to the endoplasmic reticulum, is required for early embryonic development
Authors: Kumada Tomohiro , Yamanaka Yasunari , Kitano Ayumi , Shibata Minoru , Awaya Tomonari , Kato Takeo , Okawa Katsuya , Abe Takaya , Oshima Naoko , Nakahata Tatsutoshi , Heike Toshio 
Published: June 2010

AbstractUsing comprehensive genetic studies on neuronal stem/progenitors cells through genome‐wide screening with oligonucleotide arrays, we identified an endoplasmic reticulum (ER) ‐resident protein, Tweety homologue 1 (ttyh1). Ttyh1 encodes a glycosylated protein composed of five predicted transmembrane segments and a C‐terminus that is enriched in negatively charged residues capable of Ca2+ binding. Ttyh1‐containing membranes changed to segmented tubuloreticular structures during mitosis, suggesting that the ER‐containing Ttyh1 could be responsible for Ca2+ sequestration and Ca2+ concentration regulation during mitosis. Ttyh1 inactivation in mice resulted in early embryonic lethality before organization of the nervous system, revealing that ttyh1 is essential in murine embryonic development. Our findings indicate that Ttyh1 plays an indispensable role during mitosis in early embryogenesis, possibly by maintaining Ca2+ homeostasis in the ER. Developmental Dynamics 239:2233–2245, 2010. © 2010 Wiley‐Liss, Inc.
Oda16/Wdr69 is essential for axonemal dynein assembly and ciliary motility during zebrafish embryogenesis
Authors: Gao Chunlei , Wang Guangliang , Amack Jeffrey D. , Mitchell David R. 
Published: June 2010

AbstractIn the alga Chlamydomonas reinhardtii, Oda16 functions during ciliary assembly as an adaptor for intraflagellar transport of outer arm dynein. Oda16 orthologs only occur in genomes of organisms that use motile cilia; however, such cilia play multiple roles during vertebrate development and the contribution of Oda16 to their assembly remains unexplored. We demonstrate that the zebrafish Oda16 ortholog (Wdr69) is expressed in organs with motile cilia and retains a role in dynein assembly. Antisense morpholino knockdown of Wdr69 disrupts ciliary motility and results in multiple phenotypes associated with vertebrate ciliopathies. Affected cilia included those in Kupffer's vesicle, where Wdr69 plays a role in generation of asymmetric fluid flow and establishment of organ laterality, and otic vesicles, where Wdr69 is needed to develop normal numbers of otoliths. Analysis of cilium ultrastructure revealed loss of outer dynein arms in morphant embryos. These results support a remarkable level of functional conservation for Oda16/Wdr69. Developmental Dynamics 239:2190–2197, 2010. © 2010 Wiley‐Liss, Inc.
Click Chelators – The Behavior of Platinum and Palladium Complexes in the Presence of Guanosine and DNA
Authors: Chevry Aurélien , Teyssot Marie‐Laure , Maisonial Aurélie , Lemoine Pascale , Viossat Bernard , Traïkia Mounir , Aitken David J. , Alves Georges , Morel Laurent , Nauton Lionel , Gautier Arnaud 
Published: June 2010

AbstractTriazole chelators, synthesized by click chemistry, are convenient ligands for palladium(II) and platinum(II). Conformational changes induced by the complexation of these PdII and PtII complexes with guanosine are similar to those of cisplatin. In addition, these complexes behave like cisplatin with regard to the relaxation of supercoiled plasmid DNA.
Ternary Rare Earth Inorganic–Organic Hybrids with a Mercapto‐Functionalized Si–O Linkage and a Polymer Chain: Coordination Bonding Assembly and Luminescence
Authors: Sheng Kai , Yan Bing , Lu Hai‐Feng , Guo Lei 
Published: June 2010

AbstractA series of ternary organic/inorganic/polymer hybrid materials have been assembled on the basis of the coordination chemistry principle. Mercapto‐functionalized MBA‐Si from MBA (4‐mercaptobenzoic acid) behaves as the first coordination unit, which forms sulfide linkages, resulting in an inorganic Si–O network after hydrolysis and copolycondensation with TEOS (tetraethoxysilane). The organic polymers PVPD [poly(4‐vinylpyridine)] and PMMA [poly(methyl methacrylate)] play a role of the second coordination unit, whose organic polymeric C–C chain originates from addition polymerization of the monomers 4‐VPD (4‐vinylpyridine) and MMA (methyl methacrylate), respectively. These hybrids are characterized in detail to compare with the binary hybrids without an organic polymer unit, whose results reveal that the microstructure, the thermal stability, and especially the photoluminescence properties of the hybrid system are improved with the introduction of the polymer as the coligand.
Metabolomic studies of radiation‐induced apoptosis of human leukocytes by capillary electrophoresis‐mass spectrometry and flow cytometry: Adaptive cellular responses to ionizing radiation
Authors: Lee Richard , Britz‐McKibbin Philip 
Published: June 2010

AbstractThere is growing interest in the development of new methods for elucidating the biological effects of low‐dose exposure to ionizing radiation (IR) on human health. Herein, we introduce a strategy for assessment of the impact of radiation‐induced oxidative stress on the intra‐cellular metabolism of human leukocytes. Untargeted metabolomic analyses were performed by CE‐ESI‐MS on irradiated leukocytes exposed to increasing doses of ‐radiation emitted from a Taylor source, which were subsequently incubated for 44 h to allow for cellular recovery. Flow cytometry with dual fluorescence staining revealed a major shift from early‐ to late‐stage apoptosis associated with cell membrane permeability changes as radiation dosage was increased relative to the control, but with a significant attenuation measured at intermediate dose levels. CE‐ESI‐MS analysis of filtered white blood cell lysates was also performed to quantify changes associated with 22 intra‐cellular metabolites, which were consistently measured in leukocytes across all radiation levels. Preliminary experiments demonstrated that there was an overall depletion in metabolites with extended exposure to IR; however, there was a non‐linear upregulation of specific metabolites at the 4 Gy level relative to pre‐irradiated levels, notably for arginine, glutamine, creatine, proline and reduced glutathione. Our studies demonstrate that leukocytes require a minimum threshold level of IR to induce a cytoprotective response in metabolism associated with antioxidant defense, energy homeostasis and cell signaling, which is relevant to improved understanding of the mechanisms of oxidative stress in radiobiology and cancer therapy.