bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Stress Distribution in Overdenture‐Retaining Bar with Different Levels of Vertical Misfit
Authors: Spazzin Aloísio O. , Abreu Ricardo T. , Noritomi Pedro Y. , Consani Rafael Leonardo X. , Mesquita Marcelo F. 
Published: June 2011

Abstract Purpose: To evaluate the effects of different levels of vertical misfit between implant and bar framework on distribution of static stresses in an overdenture‐retaining bar system using finite element analysis. Material and Methods: A 3D finite element model (11,718 elements and 21,625 nodes) was created and included two titanium implants and a bar framework placed in the medial region of the anterior part of a severely reabsorbed‐jaw. All materials were presumed to be linear elastic, homogenous, and isotropic. Mechanical simulation software (NEiNastran 9.0) was used, where displacements were applied on the end of the bar framework to simulate the closure of the vertical misfits (5, 25, 50, 100, 200, and 300 μm) after tightening of the screws. Data were qualitatively evaluated using Von Mises stress given by the software. Results: The models showed stress concentration in cortical bone, corresponding to the cervical part of the implant, and in cancellous bone, corresponding to the apical part of the implant; however, in these regions few changes were observed in stress to the misfits studied. While in the bar framework, retaining‐screw neck, and implant platform, a considerable stress increase proportional to the misfit amplification was observed. Conclusions: The different levels of vertical misfit did not considerably influence the static stress levels in the peri‐implant bone tissue; however, the mechanical components of the overdenture‐retaining bar system are more sensitive to lack of passive fit.
Management of Symptomatic Inadvertently Placed Endocardial Leads in the Left Ventricle
Authors: RODRIGUEZ YASSER , BALTODANO PABLO , TOWER ALBREE , MARTINEZ CLAUDIA , CARRILLO ROGER 
Published: June 2011

Background:

There are limited data regarding the clinical care of inadvertently placed endocardial leads in the left ventricle (LV). We clarified the appropriate management within the context of our experience and published literature.
Methods:

Hospital charts dating from October 2008 to December 2010 were reviewed at a high‐volume cardiovascular tertiary referral center. Six patients were identified with inadvertently placed leads in the LV through an atrial septal defect.
Results:

Six patients (four males, two females) underwent LV lead removal, four through open surgical intervention and two percutaneously. Three (50%) patients presented with severe mitral regurgitation; one (16%) with a thromboembolic transient ischemic attack and two (33%) were asymptomatic. The mean age was 68.5 ± 8.48 years (55–78). Mean ejection fraction was 38.47 ± 11.1% (25%–50%). Four patients (66%) had a pacemaker and two (33%) had implantable cardioverter defibrillators. Comorbidities consisted of diabetes mellitus (50%), chronic renal failure (16%), severe chronic pulmonary hypertension (16%), and congestive heart failure (33%). Hypertension and coronary arterial disease were present in all patients. All patients had complete extraction or repositioning without intraoperative complications or mortality within 30 days. At 6‐month follow‐up, the patient with severe pulmonary hypertension died of pneumonia and the other five were alive and well.
Conclusion:

The avoidance and early recognition of inadvertently placed endocardial leads in the LV is imperative in order to avoid potentially serious sequelae and invasive interventions. Treatment usually consists of surgical extraction, although anticoagulation and percutaneous simple traction techniques are an option in certain scenarios. (PACE 2011; 34:1192–1200)
Failure of the Active‐Fixation Mechanism during Removal of Active‐Fixation Pacing Leads
Authors: CANO OSCAR , OSCA JOAQUÍN , SANCHO‐TELLO MARÍA‐JOSÉ , OLAGÜE JOSÉ , CASTRO JOSÉ E. , SALVADOR ANTONIO 
Published: June 2011

Background:
Active‐fixation pacing leads are being widely employed due to their theoretical advantages when compared with traditional passive‐fixation leads: easy fixation and reposition, possible deployment in alternative pacing sites, lower rates of dislodgment, and chronic removability. However, the behavior of the active‐fixation mechanism during lead removal has not been yet systematically studied and may have important clinical implications.
Objective:
To evaluate if the active‐fixation mechanism was still working properly in pacing leads that were removed due to different causes.
Methods:
Thirty‐one consecutive patients undergoing active‐fixation lead removal (40 leads) were studied. Before lead removal, the helix was retracted using the appropriate tool, and fluoroscopy signs were evaluated. After removal, the helix status was examined, and the active‐fixation mechanism was once again retested when possible.
Results:
In nine of 40 leads (22.5%), the helix remained extended after lead removal in spite of having applied the number of rotations recommended by the manufacturer with the clip‐on tool. There was no linear relationship between lead longevity and the presence of an extended helix after lead removal. However, failure of the active‐fixation mechanism was more frequent among leads implanted <1 year before versus >1 year before (OR 6.8, 95% CI 1.1–42.7, P = 0.043). In 38% of patients with failure of the active‐fixation mechanism, a previous lead reposition had been attempted before lead removal due to significant pacing threshold rise.
Conclusions:
In our series, the active‐fixation mechanism failed in up to 22.5% of explanted leads. This may have important clinical implications during active‐fixation lead removal and reposition. 2011; 34:1217–1224)
1 Residential Burial in Global Perspective
Authors: Adams Ron L. , King Stacie M. 
Published: June 2011

ABSTRACTWhile the study and interpretation of mortuary practices have long been important parts of archaeological analyses, rarely has residential burial – the practice of burying the deceased in and around houses – been a specific focus of investigation. Here, we examine some of the global contexts in which residential burial has occurred and discuss the different ways that archaeologists have interpreted residential burial. Though practices vary in time, place, and context, the presence of burials in residential settings compels archaeologists to carefully consider the relationship between the living and the dead and to explore the importance of social memory, social reproduction, relations of power, mortuary ritual, and social landscapes.
2 The Social Life of Tombs in West Sumba, Indonesia
Authors: Adams Ron L. , Kusumawati Ayu 
Published: June 2011

ABSTRACTEthnoarchaeological examination of the contemporary practice of erecting stone tombs within residential compounds in West Sumba, Indonesia provides important insights into active social processes that can be associated with residential burials. Residential tombs in West Sumba reach megalithic proportions and convey not only links to past ancestors but also social dynamics associated with power negotiation, achievement, and the continuity of living groups. This study of residential burial and tomb‐building in West Sumba reveals actively changing and multifaceted social meanings linked to tombs as well as commonalities shared by both residential and monumental burials with intriguing implications for prehistoric mortuary practices.
Characteristics of patients with orofacial granulomatosis
Authors: McCartan BE , Healy CM , McCreary CE , Flint SR , Rogers S , Toner ME 
Published: June 2011

Oral Diseases (2011) 17, 696–704Objectives:  Orofacial granulomatosis has mostly been described in reports of very small numbers of cases. Few large case groups have been described. The aim of this study was to describe the demographics, symptoms, clinical features and laboratory findings in a large cohort of cases.Subjects and Methods:  Clinical and laboratory data for 119 cases of orofacial granulomatosis who attended oral medicine clinics in Dublin, Ireland, were examined for demographic characteristics at the time of first presentation. The male/female ratio was approximately 1:1, with a median age (and range) of 28 (5–84) years.Results:  Symptoms had been present for a median duration of 12 weeks. A food association was suspected by 30% of patients. The predominant complaint was lip swelling (77%) with only 15% reporting facial swelling, while 8% complained of both. Almost all patients had clinical evidence of lip or facial swelling (95%). Other common extra‐oral manifestations were lip fissuring (30%), angular cheilitis (28%) and perioral erythema (28%). Common intra‐oral manifestations were cobblestoning of the buccal mucosa (63%), ulcers (36%), granulomatous gingivitis (33%), mucosal tags (29%) and fissured tongue (17%). Over half of the biopsies (56%) performed were reported as typical of orofacial granulomatosis.Conclusion:  This is one of the largest cohorts of orofacial granulomatosis patients to have been described in detail.
Can New Stadiums Revitalise Urban Neighbourhoods?
Authors: Coates Dennis , Humphreys Brad 
Published: June 2011

Abstract
New sports stadiums and arenas bring renewal and prosperity. So at least Londoners have been promised as construction for the 2012 Olympics transforms their neighbourhoods. Are there grounds for the promises? Dennis Coates and Brad Humphreys look at the evidence from North America and find many unjustified claims.
The Sapiential Dimension of Theology according to St. Thomas
Authors: Morrissey Paul 
Published: June 2011

AbstractIn the wake of the (almost) universal rejection of neo-Thomism after the Second Vatican Council it was normal to view St. Thomas's theology within the prism of certain stereotypes. A particularly favoured generalisation said that in Thomas's theology Aristotle had trumped the Bible turning theology away from its principle source and power. In recent years however there has been a renewal in what this paper argues is a more holistic reading of St. Thomas focussing especially on his sapiential understanding of theology. Names synonymous with this renewal are Torrell, Emery, Pinckaers, Cessario, and Levering. It is the purpose of this paper to highlight the source of this more sapiential reading of St. Thomas by discussing four key dimensions of his understanding of theology: 1) what Thomas means by wisdom 2) the contemplative nature of theology 3) the unitive nature of theology 4) the importance of prayer and holiness for theology.
Anselm's Argument: On the Unity of Thinking and Being
Authors: Sultana Mark 
Published: June 2011

AbstractIn this article, I argue that at the root of the ‘ontological’ argument lies the notion that the idea of God is truth: in the idea of God, the meaning of the concept and the reality of the Being actually converge; the idea of God is God. After looking at a number of thinkers whose philosophical method is reminiscent of Anselm's I conclude that, while Anselm did not furnish a conclusive proof of the necessary existence of God, his argument shows how the question of the existence of God is one and the same with the question of the intelligibility and coherence of God and with the question of the intelligibility and coherence of reality.
Auxin‐Oxylipin Crosstalk: Relationship of AntagonistsF
Authors: Hoffmann Maik , Hentrich Mathias , Pollmann Stephan 
Published: June 2011

Abstract Stephan Pollmann (Corresponding author) Phytohormones regulate a wide array of developmental processes throughout the life cycle of plants. Herein, the various plant hormones may interact additively, synergistically, or antagonistically. By their cooperation they create a delicate regulatory network whose net output largely depends on the action of specific phytohormone combinations rather than on the independent activities of separate hormones. While most classical studies of plant hormonal control have focused mainly on the action of single hormones or on the synergistic interaction of hormones in regulating various developmental processes, recent work is beginning to shed light on the crosstalk of nominally antagonistic plant hormones, such as gibberellins and auxins with oxylipins or abscisic acid. In this review, we summarize our current understanding of how two of the first sight antagonistic plant hormones, i.e. auxins and oxylipins, interact in controlling plant responses and development.
Over‐expression of WOX1 Leads to Defects in Meristem Development and Polyamine Homeostasis in ArabidopsisF
Authors: Zhang Yanxia , Wu Renhong , Qin Genji , Chen Zhangliang , Gu Hongya , Qu Li‐Jia 
Published: June 2011

Abstract In plants, the meristem has to maintain a separate population of pluripotent cells that serve two main tasks, i.e., self‐maintenance and organ initiation, which are separated spatially in meristem. Prior to our study, WUS and WUS‐like WOX genes had been reported as essential for the development of the SAM. In this study, the consequences of gain of WOX1 function are described. Here we report the identification of an Arabidopsis gain‐of‐function mutant wox1‐D, in which the expression level of the WOX1 (WUSCHEL HOMEOBOX 1) was elevated and subtle defects in meristem development were observed. The wox1‐D mutant phenotype is dwarfed and slightly bushy, with a smaller shoot apex. The wox1‐D mutant also produced small and dark green leaves, and exhibited a failure in anther dehiscence and male sterility. Molecular evidences showed that the transcription of the stem cell marker gene CLV3 was down‐regulated in the meristem of wox1‐D but accumulated in the other regions, i.e., in the root‐hypocotyl junction and at the sites for lateral root initiation. The fact that the organ size and cell size in leaves of wox1‐D are smaller than those in wild type suggests that cell expansion is possibly affected in order to have partially retarded the development of lateral organs, possibly through alteration of CLV3 expression pattern in the meristem. An S‐adenosylmethionine decarboxylase (SAMDC) protein, SAMDC1, was found able to interact with WOX1 by yeast two‐hybrid and pull‐down assays in vitro. HPLC analysis revealed a significant reduction of polyamine content in wox1‐D. Our results suggest that WOX1 plays an important role in meristem development in Arabidopsis, possibly via regulation of SAMDC activity and polyamine homeostasis, and/or by regulating CLV3 expression.
Slovenian Renal Replacement Therapy Registry: Excerpts from the 2008 Annual Report
Authors: Buturović‐Ponikvar Jadranka , Gubenšek Jakob , Arnol Miha 
Published: June 2011

AbstractThis report provides a summary of the 2008 Slovenian Renal Replacement Therapy Registry Annual Report. Data on renal replacement therapy (RRT) were obtained from 20 dialysis centers and one transplant center, referring 31 December 2008, with 100% response rate to individual patient questionnaires. Slovenia has a population of approximately two million. The total number of patients treated by RRT was 1967, i.e. 968 per million of population (pmp), a 3.7% increase compared to 2007. In total, 1343 (68.3%) were treated by hemodialysis, 105 (5.3%) by peritoneal dialysis, and 519 (26.4%) had a functioning kidney graft. A total of 235 incident patients, 116 pmp (at day one), started RRT: their median age was 67 years, 61.8% were men, and 28% were diabetics. Regarding hemodialysis patients, 77% were dialyzed in hospital and 23% in private centers, 48% were treated with on‐line hemodiafiltration and 74% with ultrapure dialysis fluid. The median weekly duration of hemodialysis was 13.5 hours, median dry body weight 68 kg, mean blood flow 283 ± 51 mL/min, and 9.2% were dialyzed using a single‐needle mode. Vascular access was provided by a native arteriovenous fistula in 82%, a polytetrafluoroethylene graft in 6%, and a catheter in 12%. The crude death rate was 12.4% in dialysis patients, 1.4% in transplant recipients, and 9.4% in all RRT patients (both dialysis and transplant, incident patients at day 1 included). The longest survival on RRT is 38 years (with hemodialysis only). Slovenia has been a member of Eurotransplant since 2000; 52 kidney transplantations were performed in 2008, all from deceased donors.
Treatment of Anemia With Epoetin in Kidney Transplant Recipients
Authors: Bren Andrej , Arnol Miha , Kandus Aljoša , Varl Janez , Oblak Manca , Lindič Jelka , Pajek Jernej , Knap Bojan , Kovač Damjan , Mlinšek Gregor , Buturović‐Ponikvar Jadranka 
Published: June 2011

AbstractThe aim of this study was to analyze the prevalence and efficacy of renal anemia treated with epoetin in maintenance kidney transplant recipients in Slovenia. By the end of 2009, 107 out of 537 patients (19.9%) had been treated with epoetin. A cohort of 49 patients (45.8%) were analyzed in detail: 11 patients received epoetin alfa, 18 epoetin beta, 10 darbepoetin alfa, and 10 patients received methoxy polyethylene glycol‐epoetin beta. The median epoetin dose was 0.36 µg/kg body weight per week. The median serum laboratory parameters were as follows: hemoglobin 120 g/L, hematocrit 0.36, ferritin 332 ng/mL, transferrin saturation 34%, serum creatinine 145 µmol/L, serum albumin 41 g/L, intact parathyroid hormone 79 ng/L, and C‐reactive protein 3 mg/L. We concluded that the prevalence of renal anemia in kidney transplant recipients treated with epoetin was approximately 20%, and laboratory parameters suggested that the treatment of renal anemia in this study cohort was optimal.
Forty‐Eight‐Hour Ambulatory Blood Pressure and Carotid‐Femoral Pulse Wave Velocity in Hemodialysis Patients
Authors: Ekart Robert , Bernhardt Matej , Balon Breda Pečovnik , Bevc Sebastjan , Hojs Radovan 
Published: June 2011

AbstractCarotid‐femoral pulse wave velocity (cfPWV) is an important predictor of cardiovascular events in the general population and also in hemodialysis (HD) patients. In the general population, cfPWV is strongly associated with age and blood pressure (BP). The best timing and method of BP measurement in HD patients is uncertain. Ambulatory blood pressure measurements (ABPM) have been used to better define the relationship between BP, target organ damage, and outcomes in HD patients. The aim of this study was to determine the possible association between cfPWV, cardiovascular risk factors, single BP measurements, and 48‐hour ABPM in chronic HD patients. Thirty‐three HD patients (22 men, 11 women) were included. After the end of the mid‐week HD session, BP was measured, arterial stiffness was estimated by cfPWV, and 48‐hour ABPM was performed. The mean systolic and diastolic BP readings before cfPWV measurement were 136/79 mm Hg, and the mean 48‐hour systolic and diastolic BP readings were 131/76 mm Hg. The mean and range of the cfPWV measurements were 8.31 ± 2.35 m/s and 5.18–16.53 m/s, respectively. Using regression analysis, no association between cfPWV and BP before PWV measurements was found. A statistically significant correlation between cfPWV and 48‐hour systolic and diastolic ABPM was found. Using multiple regression analysis (including age, sex, smoking, diabetes, body mass index, total cholesterol, low‐ and high‐density lipoprotein cholesterol, triglycerides, C‐reactive protein, albumin, phosphorus, calcium, and iPTH) 48‐hour systolic (P < 0.001) and diastolic ABPM (P < 0.005) still remain significantly associated with cfPWV. Only 48‐hour ABPM was associated with cfPWV in HD patients in our study. We found no relationship between cfPWV and other cardiovascular risk factors.
Long‐Term Citrate Anticoagulation in Chronic Hemodialysis Patients
Authors: Gubenšek Jakob , Kovač Janko , Benedik Miha , Marn‐Pernat Andreja , Knap Bojan , Ponikvar Rafael , Buturović‐Ponikvar Jadranka 
Published: June 2011

AbstractIn some cases, long‐term (>3 months) citrate anticoagulation is needed in maintenance hemodialysis patients due to a persistent bleeding risk. In this retrospective observational study, we present our experience and assess its safety and effects on mineral and bone disorder parameters. Sixteen patients (mean age 67 ± 15 years) were treated with long‐term citrate anticoagulation. The indications were: recurrent gastrointestinal bleeding in nine patients, heparin‐induced thrombocytopenia, retroperitoneal hematoma, chronic subdural hematoma, proliferative diabetic retinopathy, vascular malformations in the brain in one patient, and others in two patients. Metabolic complications and intact parathyroid hormone (iPTH) were analyzed. Citrate anticoagulation was performed for 4 months to 6.3 years (median 12 months). Ionized calcium was stable during the procedures; hypocalcemia (<0.9 mmol/L) was rare (2.1% of procedures), and there was one case of severe symptomatic hypocalcemia. There were no clinically significant acid–base disturbances and no clotting problems. In the short term (1–3 months after starting citrate), the iPTH increased in 73% of patients (from 325 ± 310 to 591 ± 793 pg/L, P = 0.11, N = 11). In the long term (1–2 years), an increase in iPTH was observed in 3/6 patients. The time period (before/after starting citrate) was a significant predictor of iPTH using main‐effects anova (P < 0.001). To conclude, long‐term citrate anticoagulation in chronic hemodialysis patients is safe. Mild hypocalcemia during dialysis with citrate anticoagulation may contribute to a short‐ and long‐term increase in iPTH in these patients. Further studies on long‐term citrate anticoagulation are necessary.
Citrate Anticoagulation During Post‐Dilution Hemodiafiltration With a High Cut‐Off (Theralite) Membrane
Authors: Kovač Janko , Gubenšek Jakob , Pernat Andreja Marn , Buturović‐Ponikvar Jadranka , Kersnič Boštjan , Pretnar Jože , Ponikvar Rafael 
Published: June 2011

AbstractCitrate anticoagulation has not yet been described for hemodiafiltration (HDF) with high cut‐off (HCO) membranes, which can be used in the treatment of cast nephropathy secondary to multiple myeloma. A 57‐year‐old male patient with multiple myeloma and acute renal failure was treated with HDF using a HCO membrane (Theralite) each or every other day. Due to thrombocytopenia, citrate anticoagulation was done for the first 7 h, and anticoagulant‐free HDF was performed for the last hour to avoid citrate accumulation. Magnesium, phosphate, and albumin were measured after 3, 6, and 8 h, and were replaced as necessary. Thirty‐two post‐dilution HDF procedures (8 h each, infusate 24 L) were performed with blood flow at 300–330 mL/h; sodium citrate 4% was infused at 300 mL/h and 1 mol/L calcium chloride was infused at a mean rate of 14.6 ± 1.1 mL/h. Calcium‐free dialysate/infusate was used. Ionized calcium was stable (1.10 ± 0.06 before and 1.08 ± 0.06 mmol/L after HDF). Magnesium was stable (0.67 ± 0.12 before and 0.68 ± 0.05 mmol/L after HDF), with an average 390 ± 180 mg per procedure, substituted orally. There was no metabolic alkalosis or hypernatremia after the procedures, and no significant clotting was noted. The total/ionized calcium ratio (1.87 ± 0.22 before vs. 1.56 ± 0.20 after 6 h) and the corrected/ionized calcium ratio (2.02 ± 0.21 before vs. 1.88 ± 0.27 after 6 h) decreased during HDF, indicating no citrate accumulation. Citrate anticoagulation was effectively performed during 8 h of HCO membrane HDF. There were no side effects of citrate anticoagulation, nor were any signs of citrate accumulation noted.