bluuebunny/crossref_metadata_2025_split huggingface dataset:
تعزيز الأمن الفكري لدى الطلبة السعوديين المبتعثين للدراسة في الخارج "برنامج مقترح لتدخل المهني من منظور خدمة الفرد"
Authors: الفرائضي حمدة بنت عبد الله 
Published: April 2024

هدفت الدراسة الحالية إلى التحقق من فعالية برنامج مقترح للتدخل المهني في خدمة الفرد لتعزيز الأمن الفكري لدى الطلبة السعوديين المبتعثين، ولتحقيق الهدف من الدراسة استخدمت الباحثة المنهج شبه التجريبي، وتكونت عينة الدراسة من (60) طالبًا وطالبة من الطلبة السعوديين المبتعثين بلندن، وتم تقسيمهم إلى مجموعتين تجريبية وضابطة متساويتين في العدد بواقع (30) طالبًا وطالبة في كل مجموعة، وتمثلت أدوات الدراسة في كل من: مقياس الأمن الفكري، والبرنامج المقترح (كلاهما إعداد الباحثة)، وبعد إجراء التحليلات الإحصائية اللازمة توصلت الدراسة للنتائج التالية:
-	وجود فروق ذات دلالة إحصائية بين متوسطي درجات أفراد المجموعتين التجريبية والضابطة على مقياس الأمن الفكري في القياس البعدي لصالح المجموعة التجريبية.
-	وجود فروق ذات دلالة إحصائية بين متوسطي درجات أفراد المجموعة التجريبية في القياسين القبلي والبعدي على مقياس الأمن الفكري لصالح القياس البعدي.
-	تمتع البرنامج المقترح للتدخل المهني في خدمة الفرد المستخدم في الدراسة الحالية بحجم تأثير كبير في تعزيز الأمن الفكري لدى أفراد المجموعة التجريبية.
-	عدم وجود فروق ذات دلالة إحصائية بين متوسطي درجات الذكور والإناث من أفراد المجموعة التجريبية في القياس البعدي لمتغير الأمن الفكري في كل من البعد الديني، والبعد الوطني، والبعد الاجتماعي، في حين وجدت فروق ذات دلالة إحصائية بين متوسطي درجات الذكور والإناث من أفراد المجموعة التجريبية في القياس البعدي لمتغير الأمن الفكري في كل من البعد الثقافي، والبعد النفسي، والدرجة الكلية للمقياس لصالح الإناث.
-	عدم وجود فروق ذات دلالة إحصائية بين متوسطي درجات أفراد المجموعة التجريبية في القياسين البعدي والتتبعي على مقياس الأمن الفكري.
وفي ضوء ما تم التوصل إليه من نتائج قدمت الدراسة عدد من التوصيات، منها: تفعيل دور الملحقيات الثقافية في تعزيز الأمن الفكري لدى الطلاب المبتعثين، أيضًا ضرورة إقامة عدد من الدورات التدريبية وورش العمل لعزيز الأمن الفكري لدى الطلاب المبتعثين خلال فترة الابتعاث.
Dependencia emocional y satisfacción marital en mujeres adultas
Authors: Zúñiga Tirado Karen Johanna , García Ramos Diana Carolina 
Published: April 2024

Introducción: La dependencia emocional es un patrón desadaptativo, en el que la persona intenta cubrir necesidades emocionales con otros individuos. La satisfacción marital es la valoración subjetiva y global que una persona tiene hacia su pareja y su relación.
Objetivo: Determinar correlación entre dependencia emocional y satisfacción marital en mujeres adultas.
Método: La investigación es cuantitativa correlacional, de no experimental y transversal. Se aplicó el Cuestionario de Dependencia Emocional (CDE) y la Escala de Satisfacción Marital de Pick y Andrade, a 102 mujeres adultas.
Resultados y conclusiones: No se encontró correlación entre las puntuaciones totales de dependencia emocional y satisfacción marital, sin embargo, la escala de satisfacción con los aspectos emocionales del cónyuge mantiene relación leve negativa con expresión afectiva de la pareja, modificación de planes, búsqueda de atención y dependencia emocional. Por lo que a mayor satisfacción con los aspectos emocionales del cónyuge menor dependencia emocional, expresión afectiva de la pareja, modificación de planes y búsqueda de atención. La media de puntuación de dependencia emocional es 60,88 y la de satisfacción marital es 56,9. Finalmente, no se encontraron diferencias significativas en satisfacción marital con relación a su estado civil.
SGLT2 Inhibitors Extra Glycemic Potential: A Possible Novel Approach to the Prevention of Atherosclerotic Events
Authors: Silumbwe Ceaser Wankumbu  , Ji Xiao-Man  , Siame Lukundo  , Ming Xu  
Published: April 2024

Introduction: Cardiovascular diseases are a major global health concern, with atherosclerosis being a significant contributor. Diabetes mellitus is a well-known risk factor for atherosclerosis, and SGLT2 inhibitors are more effective in reducing cardiovascular disease and mortality compared to other antihyperglycemic agents in patients with type 2 diabetes. Endothelial dysfunction, VSMC phenotypic alterations, inflammation, autophagy, oxidative stress, signaling hormones and dysbiosis are crucial factors and predictors of atherosclerosis and other cardiovascular events. SGLT2 inhibitors have been shown to alleviate these components in atherosclerotic models.
Material and Methods: To proceed we analyzed and took into account all publications, including clinical trials, animal studies, in vitro observations, reviews, and meta-analyses from various scientific databases.
Results: Evidently, SGLT2i attenuate the progression of atherosclerosis by repressing vascular inflammation, oxidative stress, endothelial dysfunction, mitigating vascular smooth muscle cells function, impairing foam cell formation, preventing platelet activation and restoration of normal autophagic function.
Conclusion: Based on these findings, it can be inferred that SGLT2 inhibitors exhibit anti-atherosclerotic characteristics and may have positive implications for the management of atherosclerosis, particularly in individuals with diabetic complications.
Temperature growth profiles for five fungi isolated from a teaching laboratory in West Virginia.
Authors: Elizabeth Rea  , Robertson Laura 
Published: April 2024

Every year, fungal infections kill approximately 1.5 million people worldwide. About 90% of these invasive infections are caused by fungi from only four genera. High human body temperature serves as a growth barrier that prevents many fungal species from infecting human hosts. This study assessed the growth of five environmental fungal isolates at temperatures ranging from ambient room temperature to 39°C, above average human body temperature of 37°C. These five isolates were captured from the indoor air of a teaching laboratory at Shepherd University and identified to putative taxon through sequence of the nuclear ribosomal internal transcribed spacer (ITS) region in a previous study. All five fungal isolates grew well at ambient temperature, but did not grow well at 38°C. Specific patterns of growth between room temperature and 38°C were different for each isolate. This research was supported by a NASA-WVSGC Undergraduate Research Fellowship (ER) and a NASA-WVSGC Research Enhancement Award (LSR).
A molecular biology approach to identify Francisella tularensis proteins that interact with Band 3 of human erythrocytes.
Authors: Schreiber Rori , D'Cunha Luke , Horzempa Joseph 
Published: April 2024

Francisella tularensis is a pathogenic gram-negative bacterium that causes the zoonotic disease Tularemia. In addition, F. tularensis is classified as a Class A Bioterrorism agent by the CDC due to the ease of aerosolization and the ability of this bacterium to cause fatal infection in low doses. Previous studies suggest that invasion of mammalian erythrocytes by F. tularensis helps to increase colonization of ticks, an arthropod vector of this pathogen. Our laboratory previously found that the erythrocyte membrane glycoprotein, Band 3 is required by F. tularensis for invasion of red blood cells. Therefore, we predict that bacterial proteins interact with Band 3 to facilitate invasion. To identify these proteins, we will express codon-optimized Band 3 linked to a Glutathione-S transferase tag in F. tularensis LVS. Subsequent pull-down assays may reveal F. tularensis protein binding partners to Band 3 responsible for facilitating erythrocyte invasion.
The role of Cxcl12b in habenular axon pathfinding in zebrafish
Authors: Roberson Sara , Livingston Jordan 
Published: April 2024

The habenula is a complex region of the forebrain with multiple populations of neurons making different neurotransmitters such as dopamine, serotonin, GABA, norepinephrine, and acetylcholine. The habenula is involved in behavioral response to pain, stress, sleep, anxiety and reward.​ The habenula provides the fundamental mechanism in both survival and decision making. Axons of the habenula project to the interpeduncular nucleus (IPN) of the midbrain. Chemokine signaling has been shown to help axons reach this target. Chemokine receptor Cxcr4b is made in the habenula, while ligand Cxcl12b is produced anterior and posterior to the developing habenula. Based on this expression pattern, we hypothesize that Cxcl12b is working as a repellant and therefore, without Cxcl12b the habenular axons will project incorrectly in the anterior/posterior direction. We have identified cxcl12b mutants carrying a transgenic line that labels the habenula and its axons with GFP. However, we have not identified any males carrying the cxcl12b mutation and the transgenic line. Due to this, we will be using the gene editing technology CRISPR to cause mutation in the cxcl12b gene injust one generation. This mutation will permit us to explore the role of Cxcl12b on habenular axon pathfinding.
Screening Resorufin Pentyl Ether Analogs for Enhanced Antimicrobial Activity Against Francisella tularensis and Neisseria gonorrhoeae.
Authors: Hall Mackenzie 
Published: April 2024

Antibiotic resistance is an urgent public health threat. The CDC estimates there are approximately 2.8 million new cases of antibiotic-resistant infections annually resulting in 35,000 deaths and billions of dollars in health care costs. The development of new drugs is imperative to combat this crisis and prevent the loss of additional lives from once “curable” diseases. Resazomycins, a novel family of antibiotics, have bactericidal activity against Francisella tularensis and Neisseria gonorrhoeae. One resazomycin, resorufin pentyl ether (RPE), significantly reduces vaginal colonization by N. gonorrhoeae in a mouse model of infection. Repeated administration of RPE, however, fails to clear the infection, in contrast to a single dose of ceftriaxone, an antibiotic commonly used to treat gonorrhea, which clears the infection within 24 hours. Further characterization of resazomycins revealed the efficacy of these compounds is limited by interaction with serum albumin and reduced oxygen concentrations found within mammalian tissues. Therefore, we hypothesize that novel resazurin analogs that maintain antimicrobial activity in the presence of serum albumin and low oxygen will have improved therapeutic efficacy in vivo. Resazurin has been chemically modified to generate ether and deoxygenated compound derivatives. Six ether derivatives and two deoxygenated analogs exhibited robust antimicrobial activity against F. tularensis and N. gonorrhoeae. In the presence of serum albumin, however, reduced efficacy was observed in the six ether analogs yet activity was maintained in the deoxygenated analogs. We plan to screen the efficacy of additional ether and deoxygenated analogs against F. tularensis and N. gonorrhoeae.
A Historical Overview on Fulfillment of the Right to Basic Education Among Albanians from Middle Ages to Beginning of The Last Decade of the XX Century
Authors: Kume Enida 
Published: April 2024

Albanians are among the peoples of the Balkans who for centuries have faced the denial of the right to be educated in their native language. The attitude and action of the Ottoman occupier for the prohibition of education in the Albanian language in all Albanian regions during all occupational period was added the effect of the prohibitive action of the religious institutions and neighboring countries that aimed at the territorial annexation of Albania. The realization of the right to education in the Albanian language among Albanian people has been one of the main objectives of the Albanian National Movement for freedom and independence. The declaration of independence also marks the beginning of education in the Albanian language for Albanians as a public right. The decisions of the Vlora government were the first important efforts to realize this right. Economic and social development, the level of culture and traditions, the heritage related to long period under occupation, the geopolitical factors and developments in the first half of the century XX do not promote the process for the development of the basic education system in Albania. At the end of the second world war, Albania was the country with the highest level of illiteracy in the Balkan region. The development of the education system has been one of the main priorities of the Government in the period after the second world war. The right to education was defined as a constitutional right and basic education as a legal obligation for every Albanian citizen. During the period of the dictatorship of the proletariat, the main characteristic of the education system in Albania was its high level of ideologization.

Received: 25 December 2023 / Accepted: 25 February 2024 / Published: 23 April 2024
Albania and the European Integration
Authors: Dhamo Iris , Dhamo Ana 
Published: April 2024

This study delves into the evolution of Albania's European integration process, focusing on various critical aspects. We examine the legislative and institutional reforms undertaken by Albania to meet the Copenhagen criteria and European Union standards. Specifically, we scrutinize the sectors of justice, public administration, and fundamental rights, assessing both progress made and lingering challenges. Furthermore, we explore the economic impact of European integration on Albania, evaluating how opening up to European markets and adopting common norms have influenced economic growth, employment, and the country's competitiveness. We also analyze social dynamics, examining how the integration process has shaped Albanian society, impacting culture, education, and social cohesion. From a geopolitical perspective, we consider Albania's strategic position in the Western Balkans and how this may affect regional dynamics and the country's role within the European Union. Finally, we discuss future prospects, exploring remaining challenges and outlining the opportunities that European integration could offer to Albania politically, economically, and socially.

Received: 25 December 2023 / Accepted: 25 February 2024 / Published: 23 April 2024
Risks of Implementing Circular Economy Practices in Smes in Albania
Authors: Prendı Klarida , Elezı Besiana , Murrja Arif 
Published: April 2024

The main objective of this paper is to give an overview of the risks of implementing circular economy practices in Albanian SMEs. The methodology used for research and design in this paper will be based on a literature review, that involves systematically searching, analyzing, and synthesizing existing scholarly articles, books, and other sources related to implementing circular economy practices in SMEs. In conclusion, the adoption of circular economy principles by SMEs in Albania has the potential to improve economic and environmental sustainability but on the other hand, there are inherent risks associated with transitioning to a circular economy model for SMEs. Our research helps to focus attention on the problems of implementing circular practices in Albanian SMEs and possible interventions by the authorities in the form of regulation.

Received: 25 December 2023 / Accepted: 25 February 2024 / Published: 23 April 2024
Examining the Real Implications of the Purchasing Power Parity
Authors: Pucı Jona , Demi Mosho Albana 
Published: April 2024

This study focuses on the purchasing power between the dollar and the yuan and its usefulness in forecasting changes in exchange rates in the long run. In particular, PPP theory helps to clarify the inclination of countries with high inflation to incur a depreciation of their exchange rates. The theoretical part highlights the deviations from theory, its causes and its interconnections with other theories that analyse the relationship between exchange rates and other macroeconomic variables. Then, the validity of the theory for the USD / JPY exchange rate is examined from 1980 to 2013. The test found proof in support of the theory at 1% confidence level. Substantial emphasis is given on the effects of the asset price bubble in Japan during 1986 - 1992 and the US economic crisis of 2008 and more specifically on the behaviour of the parity during such a period of increased uncertainty.

Received: 25 December 2023 / Accepted: 25 February 2024 / Published: 23 April 2024
A review of climate change mitigation and agriculture sustainability through soil carbon sequestration
Authors: Raihan Asif 
Published: April 2024

As a result of human activities such as burning fossil fuels, organic materials, and engaging in unsustainable land practices, atmospheric carbon dioxide (CO2) levels have been steadily rising, heightening worldwide concerns about climate change. It is expected concentrations to grow and changes in CO2 sequestration in agricultural soils as a result of the industrial revolution's acceleration of CO2 emissions. These emissions have been intensified by changes in land use, such as cutting down trees, burning biomass, altering farming operations, draining natural wetlands, and using the wrong methods for managing soil. The present study utilized the systematic literature review method to investigate soil carbon sequestration options as a possible means of reducing the impact of climate change and improving agriculture sustainability. As a result of soil degradation and poor management, soil organic carbon (SOC) levels have decreased, which in turn has increased atmospheric CO2 levels. But cutting-edge land application and modern agricultural management methods have the ability to reduce CO2 emissions. Several methods exist for replenishing depleted SOC, such as repurposing marginal lands for restoration purposes, advocating for reduced or zero-tillage methods in conjunction with cover as well as residue crops, and introducing nutrient cycling through composting, manure usage, and other environmentally friendly approaches to managing soil and water. One holistic approach to fighting climate change is long-term soil carbon sequestration. Soil carbon sequestration offers a comprehensive and efficient strategy for reducing the impact of climate change by recharging depleted soils, increasing biomass production, cleaning surface and underground water sources, and compensating for CO2 emissions through fossil fuels. Soil carbon sequestration presents an exciting opportunity for management of the problems caused by contemporary changes in the environment, and the adoption of these novel approaches is essential for meeting these issues.
Penerapan Teknik Self-Regulated Learning Untuk Meningkatkan Kemandirian Peserta Didik TK Santa Anna Surabaya
Authors: Hati Angela Amanda Berlian , Abdullah Mirza Ghulam , Lestari Ayu , Habsy Bakhrudin All 
Published: April 2024

Anak Usia Dini merupakan fase dimana individu mengalami tahap perkembangan secara signifikan pada hidupnya. Kondisi tersebut membutuhkan adanya pembelajaran dan pendampingan yang tepat untuk mendukung tumbuh kembang diri peserta didik secara optimal. Hal tersebut relevan dengan sasaran pengabdian dimana adanya permasalahan mengenai memandirikan peserta didik untuk bisa melakukan aktivitas sehari-hari. Teknik Self-Regulated Learning membantu peserta didik dalam menyadari dan memahami diri sendiri akan kebutuhannya menjalani pendidikan. Secara garis besar, Self-Regulated Learning merupakan upaya yang dilakukan untuk memandirikan peserta didik dalam rangka pemahaman dan perkembangan diri dalam memperoleh pendidikan serta kehidupan sehari-hari. Pengabdian penerapan teknik Self-Regulated Learning ini bertujuan untuk memandirikan peserta didik TK Santa Anna Surabaya. Pengabdian dilakukan dengan metode Tindakan Kelas dengan cara observasi, wawancara dan dokumentasi. Self-Regulated Learning terbukti efektif untuk meningkatkan kemandirian peserta didik. Peningkatan kemandirian melalui Self-Regulated Learning dengan sasaran anak usia dini dapat lebih efektif jika dilakukan dengan memberikan penguatan (reinforcement) sebagai motivasi positif agar anak bisa melakukan instruksi.
Exploring Employability Competencies in Construction Trades: A Comparative Analysis of Bricklaying/Block Laying and Concreting Graduates in Diverse Specializations in Gombe State, Nigeria
Authors: V. Apagu, V. , A. Baba , T. Abba, A. 
Published: April 2024

The purpose of this study was to Explore the Employability Competencies in Construction Trades: A Comparative Analysis of Bricklaying/Block Laying and Concreting Graduates in Diverse Specializations in Gombe State, Nigeria. The study was guided by three research questions and three null hypotheses guided the study. The study's population comprised 85 respondents, including 21 administrators, 48 teachers, and 16 building supervisors, making sampling unnecessary due to the manageable size of the population. Data collection utilized a structured questionnaire titled "Perceived Employability Competencies Questionnaire (PECQ)," specifically designed by the researchers to align with the research questions. The questionnaire featured two sections, A and B, and underwent face validation by three experts in the Department of Technology Education at Modibbo Adama University, Yola, Adamawa State. The instrument demonstrated a high reliability coefficient of 0.83, determined through Cronbach Alpha. Data analysis for the research questions involved calculating mean and standard deviation, while ANOVA was employed to test null hypotheses at a 0.05 level of significance. Findings of the study revealed among others that 24 employability competencies in bricklaying/block laying possessed and required by Graduate Students of BBC trade. 15 employability competencies in concreting were possessed and required by Graduate Students of BBC trade. It is recommended that Students of BBC trade should be exposed to activities that involve bricklaying and block laying works so that the students can improve their competencies when performing blocklaying work. And administrators of Technical Colleges should ensure that materials for concrete practice are provided to ensure adequate skill acquisition during practical lessons.
Doświadczenie własne terapii owrzodzeń żylnych z punktu widzenia lekarza w Poradni Chorób Naczyń - na przykładzie 2 przypadków.
Authors: Joński Marcin , Joński Jakub , Jońska Karolina 
Published: April 2024

Wprowadzenie: Przewlekła niewydolność żylna (CVI) stanowi wyzwanie zdrowotne, wpływając na wydolność naczyniową i kondycję skóry kończyn dolnych. Objawy CVI, zwłaszcza w stadium C6 z aktywnymi owrzodzeniami, wymagają ukierunkowanej interwencji, jednak często podlegają długotrwałej terapii zachowawczej.

Cel: Celem tej pracy jest zilustrowanie, w jaki sposób brak przyczynowego leczenia może opóźnić terapię owrzodzeń żylnych w CVI w stadium C6. Wybór przedłużonej terapii zachowawczej uniemożliwia szybkie wdrożenie leczenia zabiegowego niezbędnego dla skutecznego gojenia owrzodzeń żylnych.

Materiały i metody: Opisano przypadki dwóch pacjentów w wieku 67 i 65 lat z aktywnymi owrzodzeniami żylnymi skóry w stopniu C6 CVI. Pacjenci byli wcześniej długotrwale leczeni zachowawczo bez znaczącej poprawy. Poprawę uzyskano dopiero wdrażając leczenie zabiegowe po skierowaniu pacjentów do specjalistycznej poradni Chorób Naczyń.

Wyniki: W obu przypadkach zastosowano endowaskularną ablacje laserową (EVLT) połączoną ze skleroterapią piankową, co doprowadziło do kompletnego zamknięcia zmienionych chorobowo żył i zagojenia owrzodzeń.

Wnioski: Wyniki pracy podkreślają wyzwania związane z długotrwałym leczeniem zachowawczym aktywnych owrzodzeń żylnych oraz argumentują za korzyściami ekonomicznymi i terapeutycznymi ukierunkowanych interwencji, takich jak EVLT i skleroterapia piankowa, w przyspieszaniu gojenia owrzodzeń żylnych i poprawie jakości życia pacjentów. Wskazane jest zwiększenie świadomości, współpracy interdyscyplinarnej i dostępności narzędzi diagnostycznych dla optymalizacji opieki nad pacjentami z CVI. Przewlekła niewydolność żylna, zwłaszcza w połączeniu z aktywnymi owrzodzeniami (C6), stanowi znaczne obciążenie społeczne i indywidualne, a skuteczne interwencje mogą istotnie poprawić wyniki leczenia.