bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of soil respiration among three temperate forests in Changbai Mountains, China
Authors: Wang Xu , Jiang Yanling , Jia Bingrui , Wang Fengyu , Zhou Guangsheng 
Published: May 2010

CO2 efflux from forest soils is an important process in the global carbon cycle; however, effects of stand age and successional status remain uncertain. We compared soil respiration and its relationship to soil carbon content, forest floor mass, root biomass, soil temperature, and soil moisture content among three temperate forest ecosystems in Changbai Mountains, northeastern China, from 2003 to 2005. Forest types included an old-growth, mixed coniferous and broad-leaved primary forest (MN), a middle-aged, broad-leaved secondary forest (BL), and a young coniferous plantation forest (CP). Average annual soil CO2 efflux at BL (1477.9 ± 61.8 g C·m–2·year–1) was significantly higher than at CP (830.7 ± 48.7 g C·m–2·year–1) and MN (935.4 ± 53.3 g C·m–2·year–1). Differences in soil temperature among those sites were not statistically significant but contributed to the differences in annual CO2 efflux. In addition, the temperature response of soil CO2 efflux was higher at MN (Q10 = 2.78) than that at BL (Q10 = 2.17) and CP (Q10 = 2.02). Our results suggest that successional stage affects soil respiration by the differences in substrate quantity and quality, environmental conditions, and root respiration.
Patterns of leaf area index during stand development in even-aged balsam fir – red spruce stands
Authors: DeRose R. Justin , Seymour Robert S. 
Published: May 2010

Leaf area index (LAI) strongly controls forest stand production. Silviculturists can easily manage this biologically important variable by quantifying its relationship to more directly manageable stand elements, such as density. Hypothesized patterns of LAI development over relative stand density (RD) in even-aged stands of balsam fir ( Abies balsamea (L.) Mill.) and red spruce ( Picea rubens Sarg.) were examined using 78 plots from the Cooperative Forestry Research Unit’s Commercial Thinning Research Network located in the Acadian forest zone in Maine. Nonlinear regression indicated that LAI was significantly related to RD, site quality, and stand top height. LAI increased nonlinearly with increasing RD holding stand top height constant. At a given RD, LAI peaked at approximately 13 m in stand top height. Site quality positively and linearly influenced LAI, but this was only apparent after crown closure, which in turn was influenced by initial stand density. Five-year trajectories of LAI–RD remeasurement data showed an increase in LAI and RD for all stands that varied by stand top height and site quality. Taken together, RD, stand top height, and site quality are strong predictors of LAI and can be used by silviculturists to manage for LAI.
A molecular approach to quantify root community composition in a northern hardwood forest — testing effects of root species, relative abundance, and diameter
Authors: Fisk Melany C. , Yanai Ruth D. , Fierer Noah 
Published: May 2010

Research on root community structure is currently limited by the methodologies available. We evaluated a molecular-sequence-based approach to quantify the relative abundance of roots from different plant species in mixed samples. We extracted DNA from mixtures of roots, amplified the trnL intron by polymerase change reaction, and identified up to 60 clones from each mixture. We tested the effects of root diameter and species on sequence representation in mixtures. Species were correctly identified in our mixtures. Recovery efficiencies were low for root diameter classes >0.3 mm compared with those <0.3 mm, and species in high abundance in the mixture had relatively low recovery efficiency. American beech ( Fagus grandifolia Ehrh.) was quantitatively underrepresented compared with yellow birch ( Betula alleghaniensis Britton) and white ash ( Fraxinus americana L.). Root identification by sequencing is accurate and can readily be applied to novel systems without new primer development. This technique will be attractive for documenting changes in relative abundances of species, especially as the cost of sequence-based analyses drops. However, the results of such analyses must be considered carefully, as root diameter distribution, abundances, and species can introduce quantifiable biases in the estimation of relative root abundance.
Factors affecting the availability of thick epiphyte mats and other potential nest platforms for Marbled Murrelets in British Columbia
Authors: Burger Alan E. , Ronconi Robert A. , Silvergieter Michael P. , Conroy Catherine , Bahn Volker , Manley Irene A. , Cober Alvin , Lank David B. 
Published: May 2010

Nest platforms (mossy pads, limbs, and deformities >15 cm in diameter) are key requirements in the forest nesting habitat of the threatened Marbled Murrelet ( Brachyramphus marmoratus (J.F. Gmelin, 1789)). Little is known about factors that affect the availability of platforms or the growth of canopy epiphytes that provide platforms. We examined variables affecting these parameters in coastal trees in British Columbia using data from 29 763 trees at 1412 sites in 170 watersheds. Tree diameter (diameter at breast height (DBH)) was the most important predictor of platform availability in the pooled data and within each of six regions. In most regions, platforms become available at DBH > 60 cm, but on East Vancouver Island, DBH needs to be >96 cm and possibly on the Central Coast >82 cm. Other regional predictors of platforms included tree height, tree species, and to a lesser extent elevation, slope, and latitude. Most (72%) trees providing platforms had epiphytes (mainly moss) covering one third or more of branch surfaces and 81% had intermediate or thick epiphyte mats. Mistletoe deformities provided <7% of platforms. Our model predictions help to define and manage suitable habitat for nesting Marbled Murrelets and also contribute to understanding forest canopy ecosystems.
Extreme Events and the General Circulation: Observations and Stochastic Model Dynamics
Authors: Sura Philip , Perron Maxime 
Published: May 2010

Abstract
This study explores the dynamical role of non-Gaussian potential vorticity variability (extreme events) in the zonally averaged circulation of the atmosphere within a stochastic framework. First the zonally averaged skewness and kurtosis patterns of relative and potential vorticity anomalies from NCEP–NCAR reanalysis data are presented. In the troposphere, midlatitude regions of near-zero skewness coincide with regions of maximum variability. Equatorward of the Northern Hemisphere storm track positive relative/potential vorticity skewness is observed. Poleward of the same storm track the vorticity skewness is negative. In the Southern Hemisphere the relation is reversed, resulting in negative relative/potential vorticity skewness equatorward, and positive skewness poleward of the storm track. The dynamical role of extreme events in the zonally averaged general circulation is then explored in terms of the potential enstrophy budget by linking eddy enstrophy fluxes to a stochastic representation of non-Gaussian potential vorticity anomalies. The stochastic model assumes that potential vorticity anomalies are advected by a random velocity field. The assumption of stochastic advection allows for a closed expression of the meridional enstrophy flux: the potential enstrophy flux is proportional to the potential vorticity skewness. There is some evidence of this relationship in the observations. That is, potential enstrophy fluxes might be linked to non-Gaussian potential vorticity variability. Thus, extreme events may presumably play an important role in the potential enstrophy budget and the related general circulation of the atmosphere.
Characteristics of Summer Stationary Waves in the Northern Hemisphere
Authors: Chen Tsing-Chang 
Published: May 2010

Abstract
Summer stationary waves in the Northern Hemisphere are separated by a midlatitude transition zone into the subtropical monsoon regime with a vertical phase reversal and the subarctic regime with a vertically uniform structure. The dynamics and maintenance mechanism of the subtropical stationary waves have been investigated in the context of monsoon circulation. Depicted in terms of streamfunction with 40-yr ECMWF Re-Analysis (ERA-40), the dynamic characteristics of stationary waves in the transition zone and the subarctic region are thus the focus of this study. The dynamics and maintenance mechanism of these waves were explored with the streamfunction budget and the velocity potential maintenance equations.
Stationary waves across the transition region consist of anticyclonic shear zones over the North Pacific and North Atlantic and a cyclonic shear zone in east Eurasia. These transition elements are linked to subtropical oceanic anticyclones and continental thermal lows. At high latitudes, a three-wave structure emerges with a weak central Eurasian trough aligned with two deep oceanic troughs. A longitudinal phase change occurs across the transition zone, but the direction of the east–west circulation associated with the transitional anticyclonic (cyclonic) zone is the same as that of the subtropical trough (high). This phase change is caused by the dynamics transition from the Sverdrup regime to the Rossby regime because of the increasing importance of relative vorticity advection. At high latitudes, relative vorticity advection becomes the dominant dynamic process in the upper atmosphere, but is negligible in the lower troposphere. This subarctic dynamic regime results in the vertically uniform structure of stationary waves. These waves are maintained by in situ diabatic heating (cooling) ahead of three subarctic troughs (ridges). Thus, the structure of the east–west circulation of subarctic stationary waves is opposite to that of subtropical stationary waves. These findings not only disclose more detailed structure and dynamics of summer stationary waves, but also provide a more complete basis to validate summer climate simulations and to search for the cause of interannual variation in summer climate.
Composite Structure of Tropopause Polar Cyclones
Authors: Cavallo Steven M. , Hakim Gregory J. 
Published: May 2010

Abstract
Tropopause polar vortices are coherent circulation features based on the tropopause in polar regions. They are a common feature of the Arctic, with typical radii less than 1500 km and lifetimes that may exceed 1 month. The Arctic is a particularly favorable region for these features due to isolation from the horizontal wind shear associated with the midlatitude jet stream, which may destroy the vortical circulation. Intensification of cyclonic tropopause polar vortices is examined here using an Ertel potential vorticity framework to test the hypothesis that there is an average tendency for diabatic effects to intensify the vortices due to enhanced upper-tropospheric radiative cooling within the vortices. Data for the analysis are derived from numerical simulations of a large sample of observed cyclonic vortices over the Canadian Arctic. Results show that there is on average a net tendency to create potential vorticity in the vortex, and hence intensify cyclones, and that the tendency is radiatively driven. While the effects of latent heating are considerable, they are smaller in magnitude, and all other diabatic processes have a negligible effect on vortex intensity.
A further investigation of the importance of pain cognition and behaviour in pain rehabilitation: longitudinal data suggest disability and fear of movement are most important
Authors: Åsenlöf Pernilla , Söderlund Anne 
Published: May 2010

Background: Tailored treatments are topical in pain rehabilitation. One key issue for correlational studies is the identification of factors having a potential causal impact on essential treatment outcomes. Objective: To study associations between pain beliefs and disability with regard to the amount and time-frame of available data. Design: A prospective, correlational design. Subjects and setting: Ninety-two patients consulting physical therapists in primary care for persistent musculoskeletal pain. Main measures: The Pain Disability Index, the Self-Efficacy Scale and the Tampa Scale of Kinesiophobia. Results: Functional self-efficacy and fear of movement/(re)injury explained variance in pain-related disability pretreatment (adj R2 = 0.41). Self-efficacy was the most salient predictor. Adding data from immediately post treatment decreased explained variance (adj R2 = 0.25). Functional self-efficacy and fear of movement/ (re)injury lost their significant contribution in favour of pain-related disability at baseline. Change scores in functional self-efficacy and fear of movement/(re)injury accounted for a modest share of explained variance in change scores of disability (adj R2 = 0.11). Fear of movement/(re)injury but not functional self-efficacy was related to a reliable change in pain-related disability. Conclusions: Longitudinal data suggest that pretreatment levels of pain-related disability and changes in fear of movement/(re)injury are most important to immediate treatment outcomes and individual reliable change. Disability and elevated fear of movement/(re)injury should therefore be addressed in tailored pain treatments.
Looking beyond the importance of life goals. The personal goal model of subjective well-being in neuropsychological rehabilitation
Authors: Conrad Nico , Doering Bettina K , Rief Winfried , Exner Cornelia 
Published: May 2010

Objective: To identify subjective importance, attainability and success of life goals and their predictive value for subjective well-being in patients with acquired brain injury. Design: Cross-sectional, descriptive. Setting: Two inpatient neurological rehabilitation centres. Participants: Patients with non-progressive neurological disorders. Interventions: Survey using questionnaires. Measures: Life goal characteristics were assessed using a life goal questionnaire (GOALS). Subjective well-being (composite score) was measured using the Center of the Epidemic Studies Depression Scale (CES-D), the Positive and Negative Affect Schedule (PANAS) and the Satisfaction With Life Scale (SWLS). Results: Fifty-nine patients participated in the study. The most important life goals are intimacy (4.59/5), achievement (3.96/5) and altruism (3.89/5). The intimacy goals are considered most attainable (4.19/5) and patients feel most successful in this domain (3.98/5). Two important predictions of the personal goal model of subjective well-being could be confirmed. First, goal attainability moderates the relation between goal importance and goal success. Second, the influence of goal importance on subjective well-being is mediated by experienced success. The most powerful predictors for subjective well-being are success in the achievement domain (β = 0.404) and discrepancy between importance and success in the intimacy domain (β = —0.276). Conclusions: The subjective well-being of neurological patients depends not only on the appraised importance of life goals but also on their attainability and success.
Rituximab plus Peg-interferon-α/ribavirin compared with Peg-interferon-α/ribavirin in hepatitis C–related mixed cryoglobulinemia
Authors: Saadoun David , Resche Rigon Mathieu , Sene Damien , Terrier Benjamin , Karras Alexandre , Perard Laurent , Schoindre Yoland , Coppéré Brigitte , Blanc François , Musset Lucile , Piette Jean-Charles , Rosenzwajg Michele , Cacoub Patrice 
Published: May 2010

AbstractTreatment of hepatitis C (HCV)–mixed cryoglobulinemia (MC) may target either the viral trigger (HCV) or the downstream B-cell clonal expansion. Prospective cohort study of 38 HCV-MC patients who received a combination of rituximab (375 mg/m2) once a week for 1 month followed by Peg-interferon-α (Peg-IFN-α; 2a, 180 μg or 2b, 1.5 μg/kg) weekly plus ribavirin (600-1200 mg) daily for 48 weeks were compared with 55 HCV-MC patients treated by Peg-IFN-α/ribavirin with the same modalities. In the whole population of HCV-MC patients (n = 93), a complete clinical response was achieved in 73.1% (68 of 93), cryoglobulin clearance in 52.7% (49 of 93), and a sustained virologic response in 59.1% (55 of 93). Compared with Peg-IFN-α/ribavirin, rituximab plus Peg-IFN-α/ribavirin–treated patients had a shorter time to clinical remission (5.4 ± 4 vs 8.4 ± 4.7 months, P = .004), better renal response rates (80.9% vs 40% of complete response, P = .040), and higher rates of cryoglobulin clearance (68.4% vs 43.6%, P = .001) and clonal VH1-69+ B-cell suppression (P < .01). Treatment was well tolerated with 11% of discontinuation resulting from antiviral therapy and no worsening of HCV RNA under rituximab. Our findings indicate that rituximab combined with Peg-IFN-α/ribavirin is well tolerated and more effective than Peg-IFN-α/ribavirin in HCV-MC.
Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response
Authors: Abès Riad , Gélizé Emmanuelle , Fridman Wolf Herman , Teillaud Jean-Luc 
Published: May 2010

Abstract
The anti-CD20 monoclonal antibody (mAb) rituximab has been used successfully for lymphoma therapy for more than 10 years. Although several direct mechanisms by which anti-CD20 mAbs act have been characterized in vitro, their specific role in clinical efficacy is still debated. Little is known about the possible antitumor immune response that they may induce in patients, despite clinical data suggesting a “vaccinal” effect. We show here that an initial treatment with anti-CD20 induces protection against human CD20-expressing tumor cells and allows immunocompetent mice to survive tumor challenge. This long-lasting protection requires the presence of the Fc portion of the anti-CD20 mAb and is achieved through the induction of a cellular immune response. Only CD4+ cells were needed at the beginning of the treatment, but both CD4+ and CD8+ cells were required after tumor challenge to achieve protection. Finally, we show that interleukin-2 treatment, given after tumor challenge, improves the overall survival rate, compared with that obtained by anti-CD20 treatment alone. These findings demonstrate that anti-CD20 mAbs exert therapeutic effects through the induction of an adaptive cellular immune response, aside from any direct mechanisms involving effectors from innate immunity.
PedHunter 2.0 and its usage to characterize the founder structure of the Old Order Amish of Lancaster County
Authors: Lee Woei-Jyh , Pollin Toni I , O'Connell Jeffrey R , Agarwala Richa , Schäffer Alejandro A 
Published: May 2010

Abstract

Background
Because they are a closed founder population, the Old Order Amish (OOA) of Lancaster County have been the subject of many medical genetics studies. We constructed four versions of Anabaptist Genealogy Database (AGDB) using three sources of genealogies and multiple updates. In addition, we developed PedHunter, a suite of query software that can solve pedigree-related problems automatically and systematically.

Methods
We report on how we have used new features in PedHunter to quantify the number and expected genetic contribution of founders to the OOA. The queries and utility of PedHunter programs are illustrated by examples using AGDB in this paper. For example, we calculated the number of founders expected to be contributing genetic material to the present-day living OOA and estimated the mean relative founder representation for each founder. New features in PedHunter also include pedigree trimming and pedigree renumbering, which should prove useful for studying large pedigrees.

Results
With PedHunter version 2.0 querying AGDB version 4.0, we identified 34,160 presumed living OOA individuals and connected them into a 14-generation pedigree descending from 554 founders (332 females and 222 males) after trimming. From the analysis of cumulative mean relative founder representation, 128 founders (78 females and 50 males) accounted for over 95% of the mean relative founder contribution among living OOA descendants.

Discussion/Conclusions
The OOA are a closed founder population in which a modest number of founders account for the genetic variation present in the current OOA population. Improvements to the PedHunter software will be useful in future studies of both the OOA and other populations with large and computerized genealogies.
"For someone who's rich, it's not a problem". Insights from Tanzania on diabetes health-seeking and medical pluralism among Dar es Salaam's urban poor
Authors: Kolling Marie , Winkley Kirsty , von Deden Mette 
Published: May 2010

Abstract
The prevalence of chronic non-communicable disease, such as type 2 diabetes mellitus (T2DM), is rising worldwide. In Africa, T2DM is primarily affecting those living in urban areas and increasingly affecting the poor. Diabetes management among urban poor is an area of research that has received little attention. Based on ethnographic fieldwork in Dar es Salam, the causes and conditions for diabetes management in Tanzania have been examined. In this paper, we focus on the structural context of diabetes services in Tanzania; the current status of biomedical and ethnomedical health care; and health-seeking among people with T2DM. We demonstrate that although Tanzania is actively developing its diabetes services, many people with diabetes and low socioeconomic status are unable to engage continuously in treatment. There are many challenges to be addressed to support people accessing diabetes health care services and improve diabetes management.
Deletions of the Derivative Chromosome 9 Do Not Influence the Response and the Outcome of Chronic Myeloid Leukemia in Early Chronic Phase Treated With Imatinib Mesylate: GIMEMA CML Working Party Analysis
Authors: Castagnetti Fausto , Testoni Nicoletta , Luatti Simona , Marzocchi Giulia , Mancini Marco , Kerim Simonetta , Giugliano Emilia , Albano Francesco , Cuneo Antonio , Abruzzese Elisabetta , Martino Bruno , Palandri Francesca , Amabile Marilina , Iacobucci Ilaria , Alimena Giuliana , Pane Fabrizio , Martinelli Giovanni , Saglio Giuseppe , Baccarani Michele , Rosti Gianantonio 
Published: May 2010

Purpose Deletions of the derivative chromosome 9 [der(9)] have been associated with a poor prognosis in chronic myeloid leukemia (CML) across different treatment modalities. In the imatinib era, the prognostic impact of der(9) deletions has been evaluated mainly in patients with late chronic-phase (CP) CML, giving partially conflicting results. Few data are available in the early CP setting. For this reason, in 2006, the European LeukemiaNet recommendations still considered der(9) deletions as a candidate adverse prognostic factor and required a careful monitoring of the patient. Patients and Methods To investigate the prognostic value of der(9) deletions in early CP CML, we performed an analysis of three prospective imatinib trials of the Italian Group for Hematological Malignancies of the Adult (GIMEMA) CML Working Party. Results A fluorescent in situ hybridization (FISH) analysis of bone marrow cells was performed at diagnosis; der(9) deletions were detected in 60 (12%) of 521 evaluable patients. At 60 months, the cumulative incidence of complete cytogenetic response and major molecular response—and the probability of event-free survival, failure-free survival, progression-free survival, and overall survival—in patients with and without deletions were not statistically different. Conclusion Our data strongly support the notion that, when investigated by FISH, der(9) deletions are not a poor prognostic factor in patients with early CP CML treated with imatinib.