bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two‐step approach of percutaneous closure of a paravalvular leak and atrial septal defect after mitral valve reoperation
Authors: Sriratanaviriyakul Narin , Hart Chari , Spies Christian 
Published: March 2011

AbstractSevere paravalvular leakage following mitral valve replacement, a rare but potentially serious complication, may result in heart failure and significant hemolysis. Reoperation is considered standard of care. However, in selected patients, re‐do sternotomy carries excessively high surgical risk. Percutaneous closure of paravalvular leaks has become a viable option for these patients. We present a case of a highly symptomatic 42‐year‐old male who underwent successful percutaneous closure of two paravalvular leaks and a post‐operative atrial septal defect after re‐do mitral valve replacement surgery. As access to the left atrium was expected to be difficult following percutaneous atrial septal defect closure, a two‐step approach of paravalvular leak closure followed by atrial septal defect closure was chosen. Difficulties of atrial septal defect closure following closure of a paravalvular leak next to the inter‐atrial septum will be discussed. © 2011 Wiley‐Liss, Inc.
The confluent balloon technique for retrograde therapy of chronic total occlusion
Authors: Zhang Bin , Wong Aaron 
Published: March 2011

AbstractCoronary chronic total occlusions (CTO) remain one of the most challenging lesions in percutaneous coronary intervention (PCI). Retrograde approach is an advanced PCI technique and can improve success rate in CTO intervention. Although success rate of this technique is high in experienced hands, there are still limitations in this approach, e.g., failure of wire to cross lesions. We report an easy and reliable new method of wire crossing in CTO lesions. In this technique, when both the antegrade and retrograde wires are in the subintimal space, balloons catheters are delivered in both directions to the site of the CTO. The balloons are then inflated simultaneously to create a common subintimal space (the confluent of subintimal space) which will allow crossing of wire to true lumen, either antegradely or retrogradely. This technique may improve the success rate of wire crossing and successful CTO intervention. © 2011 Wiley‐Liss, Inc.
Application of penetration device (Tornus) for percutaneous coronary intervention in balloon uncrossable chronic total occlusion—procedure outcomes, complications, and predictors of device success
Authors: Fang Hsiu‐Yu , Lee Chien‐Ho , Fang Chih‐Yuan , Lin Cheng‐Jui , Wu Cheng‐Ching , Yang Cheng‐Hsu , Chen Chien‐Jen , Hsieh Yuan‐Kai , Yip Hon‐Kan , Wu Chiung‐Jen 
Published: March 2011

AbstractObjective: To evaluate procedure outcomes, complications, and the predictors of device success while using the Tornus in CTO revascularization. Background: The success of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) may be limited by the presence of severe calcified CTO lesions, especially in the smallest balloon uncrossable arteries. A penetrating device (Tornus) could improve the success rate. Methods: Device and angiographic success rates as well as procedural complications were assessed in 56 patients, who were consecutively and retrospectively enrolled into this study. Device success was defined as successful passage of the Tornus catheter through a CTO lesion. Procedure success was defined by a final TIMI 3 flow and <30% residual stenosis. Results: The device success rate was 71.4% in 40 patients and failure rate was 28.6% in 16 patients. The final procedure success was significantly higher in the Tornus success group compared with the Tornus failure group (87.5% vs. 37.5%, P < 0.001). One patient in the Tornus success group (1.8%) had wire perforation resulting in cardiac tamponade and cardiac death. Another patient (1.8%) in the Tornus success group had acute in‐stent thrombosis and non‐Q MI in 24 hr and was resuscitated by emergent PCI. The only independent predictor of device success was a calcium score < 2 (odds ratio (OR): 3.86 (95% CI: 1.14–13.1, P = 0.03). Conclusion: The Tornus catheter can be used in severe calcified CTO PCI when the calcium score <2 and not be used in patients with a calcium score ≥2. © 2011 Wiley‐Liss, Inc.
Sequential CoreValve implantation for a mal‐positioned prosthesis during transcatheter aortic valve implantation
Authors: Ong Sea Hing , Mueller Ralf , Gerckens Ulrich 
Published: March 2011

AbstractTranscatheter aortic‐valve implantation is rapidly emerging as an effective, safe, and sustainable alternative for a specific subset of high‐surgical risk and/or inoperable patients with severe aortic stenosis. However, technical challenges remain for this relatively new procedure, not the least mal‐positioning of the transcatheter prosthesis resulting in acute aortic regurgitation. We report a case of deep implantation of a CoreValve prosthesis that was inadvertently pulled out of the aortic annulus during repositioning. The patient received a second sequential CoreValve successfully.© 2010 Wiley‐Liss, Inc.
Drug eluting versus bare metal stents in cardiac allograft vasculopathy
Authors: Dasari Tarun W. , Hennebry Thomas A. , Hanna Elias B. , Saucedo Jorge F. 
Published: March 2011

AbstractBackground: Cardiac allograft vasculopathy (CAV) is a distinct pathological condition characterized by diffuse and progressive arteriopathy and it is an important determinant of long‐term graft survival. Definitive CAV treatment is retransplantation but palliation with stenting might temporarily alleviate it. The benefit of drug eluting stents (DES) over bare metal stents (BMS) in the treatment of such lesions is debatable. We therefore sought to do a literature search to review the available evidence comparing DES to BMS. Methods: We conducted Pub Med, EMBASE, Cochrane database review, Web of Science search of studies comparing DES with BMS in CAV. Available studies were retrospective in nature with either direct comparison groups (n = 5) or historical controls (n = 1). The main outcomes analyzed were in stent restenosis (ISR) during follow‐up and clinical outcomes. Results: A total of 312 patients from six studies were included in the review (1995–2007). Most commonly used DES were sirolimus eluting stent. DES appeared to reduce the long‐term risk of ISR compared with BMS. Three of the five studies showed a statistically significant reduction in ISR at 12 months while the one study assessing ISR at 6 months showed no significant difference. Clinical endpoints such as death and major adverse cardiac events were not statistically different. Conclusion: DES appear to reduce the incidence of ISR in CAV as compared with BMS. Prospective randomized clinical trials are needed to determine the clinical benefit of DES beyond a reduction in ISR. © 2011 Wiley‐Liss, Inc.
Papillary muscle rupture
Authors: de la Torre Hernandez Jose M. , Gorria Gonzalo Martin , Vazquez de Prada Jose A. , Zueco Javier 
Published: March 2011

AbstractWe report a not previously described complication in a retrograde transcatheter aortic valve implantation procedure: A fatal rupture of a papillary muscle producing massive regurgitation. We found papillary muscle head calcification as an anatomical substrate that could facilitate this complication.© 2011 Wiley‐Liss, Inc.
Three‐dimensional external beam radiotherapy for prostate cancer increases the risk of hip fracture
Authors: Elliott Sean P. , Jarosek Stephanie L. , Alanee Shaheen R. , Konety Badrinath R. , Dusenbery Kathryn E. , Virnig Beth A. 
Published: March 2011

AbstractBACKGROUND:Hip fracture is associated with high morbidity and mortality. Pelvic external beam radiotherapy (EBRT) is known to increase the risk of hip fractures in women, but the effect in men is unknown.METHODS:From the Surveillance, Epidemiology, and End Results (SEER)‐Medicare database, 45,662 men who were aged ≥66 years and diagnosed with prostate cancer in 1992‐2004 were identified. By using Kaplan‐Meier methods and Cox proportional hazards models, the primary outcome of hip fracture risk was compared among men who received radical prostatectomy (RP), EBRT, EBRT plus androgen suppression therapy (AST), or AST alone. Age, osteoporosis, race, and other comorbidities were statistically controlled. A secondary outcome was distal forearm fracture as an indicator of the risk of fall‐related fracture outside the radiation field.RESULTS:After covariates were statistically controlled, the findings showed that EBRT increased the risk of hip fractures by 76% (hazards ratio [HR], 1.76; 95% confidence interval [CI], 1.38‐2.40) without increasing the risk of distal forearm fractures (HR, 0.80; 95% CI, 0.56‐1.14). Combination therapy with EBRT plus AST increased the risk of hip fracture 145% relative to RP alone (HR, 2.45; 95% CI, 1.88‐3.19) and by 40% relative to EBRT alone (HR, 1.40; 95% CI, 1.17‐1.68). EBRT plus AST increased the risk of distal forearm fracture by 43% relative to RP alone (HR, 1.43; 95% CI, 0.97‐2.10). The number needed to treat to result in 1 hip fracture during a 10‐year period was 51 patients (95% CI, 31‐103).CONCLUSIONS:In men with prostate cancer, pelvic 3‐D conformal EBRT was associated with a 76% increased risk of hip fracture. This risk was slightly increased further by the addition of short‐course AST to EBRT. This risk associated with EBRT must be site‐specific as there was no increase in the risk of fall‐related fractures in bones that were outside the radiation field. Cancer 2011. © 2011 American Cancer Society.
Association of area sociodemographic characteristics and capacity for treatment with disparities in colorectal cancer care and mortality
Authors: Haas Jennifer S. , Brawarsky Phyllis , Iyer Aarthi , Fitzmaurice Garrett M. , Neville Bridget A. , Earle Craig 
Published: March 2011

AbstractBACKGROUND:Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives.METHODS:Surveillance, Epidemiology and End Results Program–Medicare data for seniors diagnosed with CRC were linked to area measures of the sociodemographic characteristics and the capacity of surgeons, medical oncologists, and radiation oncologists. Outcomes included receipt of stage‐appropriate CRC care and mortality.RESULTS:After adjustment, blacks and Hispanics were less likely than whites to undergo surgery (odds ratio [OR] 0.57, 95% confidence interval (CI) 0.52‐0.63 and OR 0.82, 95% CI 0.70‐0.95, respectively). Individuals who lived in areas with the highest tertile of surgeon capacity were more likely to undergo resection than those in the lowest, and use of surgery declined as the percentage of blacks in the area increased. Adjustment for the area measures resulted in a modest decline in disparities in care relative to whites (5.3% for black). Blacks also experienced greater all‐cause and cancer‐specific mortality than whites. Further adjustment for area sociodemographics and surgeon capacity reduced the disparity in mortality between blacks and whites. Although there was a similar black/white disparity in the use of adjuvant chemotherapy, the disparity remained after adjustment for area characteristics, although use of chemotherapy was greater in areas with the greatest capacity of medical oncologists.CONCLUSIONS:Sociodemographic characteristics and measures of the availability of specialized cancer providers in the area in which an individual resides modestly mediated disparities in the receipt of CRC care and mortality, suggesting that other factors may also be important. Cancer 2011;. © 2011 American Cancer Society.
Practical management of patients with chronic myeloid leukemia
Authors: Cervantes Francisco , Mauro Michael 
Published: March 2011

AbstractAlthough imatinib has been used as frontline therapy for chronic myeloid leukemia (CML) for nearly a decade, current debate is focused on the incorporation of newer tyrosine kinase inhibitors (TKIs) at diagnosis in light of recent US Food and Drug Administration approval of nilotinib and dasatinib for initial therapy in chronic‐phase CML. Articles were identified through a PubMed search and a review of abstracts from relevant hematology congresses. Additional information was provided from the authors' libraries and expertise. With several therapies now available, it is crucial to carefully define and monitor response in patients with CML to determine whether their treatment is appropriate and is providing an optimal outcome. Different patterns of response to TKI treatment have been recognized, ranging from best‐case scenarios of rapid and unwavering response to difficult situations of intolerance and resistance, either primary or secondary. Patients who develop resistance to imatinib are advised to switch to second‐generation TKIs. Although specific mutations in the breakpoint cluster region–v‐abl Abelson murine leukemia viral oncogene (BCR‐ABL) kinase domain may guide treatment selection in such scenarios, the choice is driven by other factors in the majority of patients, including the toxicity profiles of the newer TKIs as well as a patient's comorbidities. Cancer 2011;. © 2011 American Cancer Society.
Assigning Predissociation Infrared Spectra of Microsolvated Hydronium Cations H3O+⋅(H2)n (n=0, 1, 2, 3) by Ab Initio Molecular Dynamics
Authors: Baer Marcel , Marx Dominik , Mathias Gerald 
Published: March 2011

AbstractMessenger predissociation spectroscopy is an important experimental method to obtain vibrational spectra of molecular ions or complexes such as protonated water clusters H+⋅(H2O)n in the gas phase. However, the molecular properties and thus the linear infrared spectra may be modified upon microsolvation with typical messengers such as H2 molecules or noble gas atoms. Employing ab initio molecular dynamics for the H2‐microsolvated hydronium ion, we investigate these effects explicitly as a function of an increasing number of messengers up to filling the first microsolvation shell, that is, for H3O+⋅(H2)n (n=0, 1, 2, 3). We find that microsolvation with H2 lowers the inversion barrier of the hydronium core, which governs the inversion tunnel splitting due to umbrella motion, and thus accelerates the inversion dynamics. By comparison to experiment a comprehensive band assignment for the OH stretching region is given, and thereby the observed blueshift of stretching bands with increasing n is explained. Furthermore, detailed analyses reveal intricate intra‐ and intermolecular anharmonic mode couplings induced by the messengers, which yield a rich vibrational dynamics in these, at first glance, simple systems. Finally, the virtues but also the shortcomings of the ab initio molecular dynamics approach to vibrational spectroscopy are discussed.
Image Manipulation for High Temperature Plasmas
Authors: Murari A. , Vega J. , Mazon D. , Delmond J.F. , Gelfusa M. , Szappanos A. , JET‐EFDA Contributors  
Published: March 2011

AbstractIn magnetic confinement Nuclear Fusion video cameras have become routine diagnostics, which can produce gigabytes of data per discharge. New tools and methods are required to manipulate the frames of these videos to obtain the required information. New algorithms have been developed, which implement pattern recognition methods to search the repositories of videos on the basis of their content and not on their address. Real time automatic analysis of videos has motivated the development of machine learning tools to classify objects in images. The identification and tracking of objects in the videos of Tokamak diagnostics requires the computation of image descriptors, which are insensitive to rotation, translation and rescaling. The Hu moments have proved to be quite effective in performing this image analysis task (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Diagnostics of Low Temperature Plasmas by Optical Means
Authors: Pawelec E. 
Published: March 2011

AbstractIn this paper a short overview of the diagnostics of low temperature plasmas by optical means is presented. It is described how the results of the optical measurements, namely the intensities and profiles of the spectral lines can be used for measuring the low temperature plasma parameters ‐ temperatures, electron density, plasma velocity, magnetic and electric field in the plasma etc. Discussed are the strengths and limitations of these methods (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
On the Optical Characterisation of Nanoparticle and their Aggregates in Plasma Systems
Authors: Onofri F.R.A. , Wozniak M. , Barbosa S. 
Published: March 2011

AbstractThis paper outline and discuss basic considerations for the optical characterization of nanoparticles and their aggregates: particle models, light scattering theories and main experimental setups, regarding their interest for the study of plasma flows. It emphasizes that there are now powerful alternatives to the Lorenz‐Mie theory and its simple homogeneous sphere model, which allow accurate calculations of the optical properties of particles with complex sub‐structures and shapes (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Collective Light Scattering for the Study of Fluctuations in Magnetized Plasmas: The Hall Thruster Case Study
Authors: Tsikata S. , Honoré C. , Grésilon D. , Lemoine N. 
Published: March 2011

AbstractCollective light scattering (CLS) has been recently extended to the observation of Hall effect thruster plasmas. A better understanding of the physics of Hall thrusters is key to improving thruster operation and lifetimes. In particular, the origins of thruster phenomena such as anomalous electron transport need to be determined. A high‐performance CLS diagnostic has therefore been developed for identifying and measuring electron density fluctuations in the thruster, at millimetric length scales and MHz frequencies. Such modes are believed to play a role in anomalous transport, and experiments so far performed have provided information on their dispersion relations, amplitude and directivity. This work describes the technical aspects of the optical bench and the range of accessible experiments (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Time‐Resolved Diagnostics of Dual High Power Impulse Magnetron Sputtering With Pulse Delays of 15 µs and 500 µs
Authors: Stranak V. , Drache S. , Cada M. , Hubicka Z. , Tichy M. , Hippler R. 
Published: March 2011

AbstractTime‐resolved measurements have been performed during dual High Power Impulse Magnetron Sputtering (dual‐HiPIMS) with two cathodes in a closed magnetic field configuration. The effect of a delay between subsequent pulses on electron density, mean electron energy, and ion flux to the substrate was investigated by time‐resolved diagnostic methods. Two different delays of 15 µs and 500 µs between subsequent pulses were investigated. The dual‐HiPIMS system, operated at a repetition frequency f = 100 Hz and duty cycle of 1 %, was equipped with different metallic targets (Ti, Cu). It is shown that a delay between subsequent pulses influences the plasma parameters and can be used to control deposition processes. It was noted that target surfaces (alternately serving as a cathode/anode) are contaminated by sputtered material from the previous pulse which influences the time‐evolution of the discharge parameters (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Oxidation of NO Into NO2 by Surface Adsorbed O Atoms
Authors: Guaitella O. , Hübner M. , Marinov D. , Guerra V. , Pintassilgo C.D. , Welzel S. , Röpcke J. , Rousseau A. 
Published: March 2011

AbstractPlasma‐surface interactions are increasingly recognised as a key factor in explaining molecule production and conversion processes. In order to scrutinise such effects well‐defined surface and gas phase conditions are required. Hence, the inner surface of a Pyrex tube was treated by a capacitively coupled RF plasma at low pressure. The post‐plasma oxidation of gas mixtures containing 1 % NO into NO2 has been studied by means of quantum cascade laser absorption spectroscopy in the mid‐infrared spectral range. The plasma pre‐treatment experiments with oxygen containing precursors suggest O atom adsorption on the Pyrex tube with a surface density of 2.7 x 1014 cm–2. A simple kinetic model was developed and shows good agreement with the measured NO and NO2 gas phase concentrations. In the model a fraction of the surface is considered to be covered with chemisorption sites where atoms and molecules can be adsorbed, whereas they can be removed only by recombination (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Imaging Techniques for Microwave Diagnostics
Authors: Tobias B. , Donné A.J.H. , Park H.K. , Boom J.E. , Choi M.J. , Classen I.G.J. , Domier C.W. , Kong X. , Lee W. , Liang T. , Luhmann N.C. , Munsat T. , Yu L. , Yun G.S. 
Published: March 2011

AbstractImaging diagnostics, such as Electron Cyclotron Emission Imaging (ECEI) and Microwave Imaging Reflectometry (MIR), exhibit unique characteristics that make them particularly well suited to the validation of theoretical models for plasma instabilities and turbulent fluctuations. A 2‐D picture of plasma phenomena is provided unambiguously, from localized, time‐resolved measurements. After more than a decade of development and successful demonstrations on RTP [1,2] and TEXTOR [3, 4, 5, 6], ECEI has come into maturity as an electron temperature diagnostic technique, and systems at ASDEX‐UG [7] and DIII‐D [8] are making regular contributions to plasma physics. The next generation ECEI diagnostic is currently being installed on KSTAR [9, 10]. MIR is a radar reflectometric density fluctuation diagnostic, and hence the perfect complement to ECEI when realized to simultaneously image the same plasma volume. Experiments with MIR at TEXTOR have guided a recent surge in analysis and laboratory experiments aimed at resolving remaining issues [11, 12]. Both techniques are discussed in this tutorial with brief examples of data which illustrate the capabilities of these techniques and motivate future development for application on ITER and burning plasma experiments to come (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Copper Seed Layer Deposition by a New Liquid Precursor
Authors: Kang Sang‐Woo , Shin Yong‐Hyeon , Kim Jin‐Tae , Yun Ju‐Young , Chang Yun‐Hee , Yang Il‐Doo 
Published: March 2011

AbstractCu(hfac)2(TEA) (hfac = 1,1,1,5,5,5‐hexafluoroacetylacetonate, TEA (triethylamine, N(C2H5)3)) is a new liquid CuII precursor. Using Cu(hfac)2(TEA), we successfully deposit Cu thin films as a seed layer, even at the low deposition temperature of 373 K. To explain this behavior, the bonding status of Cu(hfac)2 in the presence of TEA is determined by density‐functional theory. The theoretical bond length of Cu‐O in Cu(hfac)2 is significantly greater (by 0.06 Å) than that without an adduct ligand.
A Metallocorrole with Orthogonal Pyrrole Rings
Authors: Thomas Kolle E. , Conradie Jeanet , Hansen Lars K. , Ghosh Abhik 
Published: March 2011

AbstractIn contrast to sterically hindered metalloporphyrins, which are almost always strongly nonplanar, similarly substituted metallocorroles are generally relatively planar. A crystal structure of a copper β‐octakis(trifluoromethyl)‐meso‐triarylcorrole, however, has revealed a corrole macrocycle with an unprecedented degree of saddling. With the exception of the bipyrrole unit, any two adjacent pyrrole rings are essentially orthogonal to each other. Furthermore, the C2‐symmetric molecular structure is chiral and NMR spectroscopy and DFT calculations suggest that the enantiomers do not interconvert readily. Once resolved, the molecule may provide us with a novel example of an inherently chiral chromophore.