bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reservoir compartmentalization: get it before it gets you
Authors: Smalley P. C. , Muggeridge A. H. 
Published: November 2010

Abstract
This paper examines the impact of compartmentalization on oil recovery, the importance of identifying it during field appraisal, and methods to evaluate it using fluid data. The impact on recovery factor is highlighted using a global database of oil field recovery factors as a function of reservoir complexity and compartmentalization, and emphasized in two case studies. The effect of compartmentalization on oil recovery demonstrates the benefit in characterizing compartmentalization correctly during appraisal, so that the field can be developed in an optimal manner.
Early characterization of field compartmentalization requires making maximum use of available fluid data during appraisal. When interpreting fluid data to identify compartmentalization, it is critical to take into account the different time-scales for various fluid signals (pressure, contacts, density, composition) to equilibrate, and to be able to extrapolate to field production time-scales. This is essential to avoid false negatives (compartments assumed absent due to homogeneous fluid properties, when in fact fluids would have equilibrated even in the presence of compartments), false positives (where fluid differences are interpreted as evidence of compartments when in fact there has not been sufficient time for equilibration to occur), and to resolve apparently conflicting data (some fluid indicators are at equilibrium, others are not). Rigorous simulation of fluid equilibration is a complex multiphase multidimensional process, and is generally reserved for specialist in-depth studies. However, order-of-magnitude evaluations can be made using analytical solutions in minutes, allowing many ‘what-if’ scenarios to be considered and uncertainty to be assessed.
Analytical solutions for estimating the time required for spatially-varying fluid properties to revert to steady state distributions are reviewed. All these mixing processes are shown to be diffusive in character. An effective diffusion coefficient for each process can be calculated from the reservoir rock and fluid properties. For an isothermal system, the different time-scales and distances for each fluid‐property variation to attain equilibrium can be compared on a single graph. Where the time elapsed since fluid‐perturbation is known, analytical solutions can be used to estimate the degree of compartmentalization (e.g. permeability of barriers). These solutions lend themselves to the development of simple practical compartment-assessment tools for industry practitioners.
Knowledge and Beliefs about Smoking and Cancer among Women in Five European Countries
Authors: Li Qian , Dresler Carolyn , Heck Julia E. , Allwright Shane , Haglund Margaretha , Sanchez Sara , Kralikova Eva , Stucker Isabelle , Tamang Elizabeth , Gritz Ellen R. , Hashibe Mia 
Published: November 2010

AbstractBackground: Lung cancer mortality in women is increasing across Europe, reflecting the alarming increase in smoking prevalence. Understanding women's perception of smoking may help to identify ways to reduce its prevalence and prevent uptake of smoking. The aim of this study was to examine factors associated with knowledge and beliefs about smoking and cancer among European women.Methods: A cross-sectional landline telephone survey on health attitudes and knowledge was conducted in five European countries: France, Ireland, Italy, the Czech Republic, and Sweden. A general linear modeling was used to explore the factors related to knowledge and beliefs about smoking and cancer.Results: A total of 5,000 women were interviewed (1,000 women from each country). The mean knowledge and belief scores about smoking and cancer were lower in current smokers than those of never and former smokers (P &lt; 0.05). Women with above-the-median income (P = 0.001) and women who held skilled occupations seemed to be more knowledgeable about tobacco health risks (P &lt; 0.001). The number of friends and family who smoked was inversely associated with knowledge on the harmful effects of tobacco (P = 0.001). Swedish women were the most knowledgeable about tobacco-related cancer risk, whereas in France and Italy, current smokers were less knowledgeable.Conclusions: Knowledge and beliefs about cancer and smoking varied significantly by smoking status.Impact: Results emphasize the need to develop health education programs that enhance cancer knowledge among women who currently smoke and are in low socioeconomic groups. Cancer Epidemiol Biomarkers Prev; 19(11); 2811–20. ©2010 AACR.
Body Size, Weight Change, and Risk of Colon Cancer
Authors: Bassett Julie K. , Severi Gianluca , English Dallas R. , Baglietto Laura , Krishnan Kavitha , Hopper John L. , Giles Graham G. 
Published: November 2010

AbstractBackground: Epidemiologic studies have consistently reported positive associations between obesity and colon cancer risk for men, but the evidence is less consistent for women. Few studies have investigated effects of weight change on colon cancer risk.Methods: Using the Melbourne Collaborative Cohort Study, which recruited men and women mostly in 40 to 69 years of age, we investigated associations between weight and body mass index (BMI) at age 18 years and at study entry and weight change since age 18 years and colon cancer. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using Cox regression.Results: During follow-up of 16,188 men and 23,438 women for 14 years on average, we ascertained 569 incident colon cancers. Weight and BMI at study entry were positively associated with colon cancer risk for men [HR, 1.12 (95% CI, 1.04-1.21) per 5-kg increment; HR, 1.39 (95% CI, 1.12-1.71) per 5 kg/m2], but not women. Risk of colon cancer was not associated with weight or BMI at age 18 years. Adult weight change was positively associated with colon cancer risk for men (HR, 1.11 per 5-kg increment; 95% CI, 1.03-1.20), but not women (HR, 1.00; 95% CI, 0.94-1.07). Men who gained ≥20 kg from age 18 had an increased risk of colon cancer compared with men whose weight was stable (HR, 1.47; 95% CI, 0.94-2.31).Conclusion: Weight gain during adult life increases men's risk of colon cancer.Impact: Avoiding excessive weight gain might help reduce colon cancer risk for men. Cancer Epidemiol Biomarkers Prev; 19(11); 2978–86. ©2010 AACR.
Association of Albuminuria and Cancer Mortality
Authors: Lin Yu-Sheng , Chiu Fu-Chun , Lin Jou-Wei , Hwang Juey-Jen , Caffrey James L. 
Published: November 2010

Abstract
Background: The objective was to evaluate the association of albuminuria with cancer mortalities in adults ages 50 and older.
Methods: A total of 6,112 adults ages 50 years and above without a history of cancer at baseline in the Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994) were included in the analysis. Albuminuria was measured with urinary albumin-to-creatinine ratio (UACR) in mg/mmol. Cancer mortality was obtained from the NHANES III–linked follow-up database (up to December 31, 2006). Cox-regression models were used to examine the associations of interest.
Results: Albuminuria was present in 705 men (17.5%) and 592 women (14.3%). During an average follow-up of 149 months, 613 subjects died of cancers including 184 lung cancers, 65 colorectal cancers, 55 prostate cancers, and 309 other cancers. There was an increased mortality risk associated with logarithmically transformed UACR for all-cancer [relative risk (RR), 1.20; 95% confidence interval (CI), 1.06-1.36], lung cancer (RR, 1.22; 95% CI, 1.05-1.43), and prostate cancer mortality (RR, 1.40; 95% CI, 1.01-1.95) in men. No associations between UACR and cancer were apparent in women.
Conclusions: The analysis shows that albuminuria is associated with an increased risk of cancer death, specifically for all-cause, lung, and prostate cancers in men ages 50 and above.
Impact: Further studies are needed to explore the relationship between albuminuria and specific cancers. Understanding the biological link between albuminuria and cancer will be critical for determining whether albuminuria represents an early marker or a potential therapeutic target. Cancer Epidemiol Biomarkers Prev; 19(11); 2950–7. ©2010 AACR.
No Effect of Exercise on Insulin-Like Growth Factor-I, Insulin, and Glucose in Young Women Participating in a 16-Week Randomized Controlled Trial
Authors: Arikawa Andrea Y. , Kurzer Mindy S. , Thomas William , Schmitz Kathryn H. 
Published: November 2010

Abstract
Introduction: Insulin-like growth factor I (IGF-I) and IGF binding protein 3 (IGFBP-3) have been associated with increased risk of breast cancer.
Methods: We report our findings on the effects of 16 weeks of aerobic exercise on IGF axis proteins, insulin, glucose, and insulin resistance of 319 young sedentary women. Demographics, health surveys, body composition, dietary intake, and blood samples were collected at baseline and 16 weeks. IGF-I and IGFBP-1, IGFBP-2, and IGFBP-3 were measured by ELISA.
Results: Exercise adherence was 88%. The dropout rates for the exercise and control groups were 21.7% and 14.5%, respectively. There was a small significant change from baseline in IGFBP-3 concentrations. IGFBP-3 levels decreased in controls and increased in exercisers. The between-group difference was significant. No other changes were noted.
Conclusion: Sixteen weeks of exercise had minimum or no effect on IGF proteins of young women.
Impact: Our study supports findings from previous studies conducted in older populations and raises the question of what type of intervention is needed to change circulating levels of IGF proteins in humans. Cancer Epidemiol Biomarkers Prev; 19(11); 2987–90. ©2010 AACR.
Chemoprevention of Pancreatic Cancer: Ready for the Clinic?
Authors: Logsdon Craig D. , Abbruzzese James L. 
Published: November 2010

Abstract
Advances in our molecular, clinical, and epidemiologic understanding of the risk and development of pancreatic cancer offer hope for preventing this disease, which is largely intractable once developed. This perspective on provocative, genetically engineered mouse model work reported by Mohammed et al. (beginning on page 1417 in this issue of the journal) examines the prospects for pancreatic cancer chemoprevention with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). Despite having limited value in advanced pancreatic cancer, EGFR TKIs show promise in the setting of early pancreatic carcinogenesis. Cancer Prev Res; 3(11); 1375–8. ©2010 AACR.
Medium-dose riboflavin as a prophylactic agent in children with migraine: A preliminary placebo-controlled, randomised, double-blind, cross-over trial
Authors: Bruijn Jacques , Duivenvoorden Hugo , Passchier Jan , Locher Heiko , Dijkstra Natascha , Arts Willem-Frans 
Published: November 2010

Background: Riboflavin seems to have a promising effect on migraine in adults. The present study examines whether riboflavin has a prophylactic effect on migraine in children. Objective: To investigate whether riboflavin in a dosage of 50 mg/day has a prophylactic effect on migraine attacks in young children. Subjects and methods: This randomised, placebo-controlled, double-blind, cross-over trial included 42 children (aged 6–13 years) with migraine of whom 14 children were also suffering from tension-type headache. Following a 4-week baseline period, all children received placebo for 16 weeks then riboflavin for 16 weeks (or vice versa) with a washout period of 4 weeks in between. The primary outcome measure was reduction in mean frequency of migraine attacks and tension-type headache in the last 4 weeks at the end of the riboflavin and placebo phase, compared with the preceding baseline or wash-out period. Secondary outcome measures were mean severity and mean duration of migraine and tension-type headaches in the last 4 weeks at the end of the riboflavin and placebo phase, compared with the preceding baseline or wash-out period. Results: No significant difference in the reduction of mean frequency of migraine attacks in the last month of treatment was found between placebo and riboflavin ( P = 0.44). However, a significant difference in reduction of mean frequency of headaches with a tension-type phenotype was found in favour of the riboflavin treatment ( P = 0.04). Conclusions: In this group of children with migraine, there is no evidence that 50 mg riboflavin has a prophylactic effect on migraine attacks. We found some evidence that 50 mg riboflavin may have a prophylactic effect on interval headaches that may correspond to mild migraine attacks or tension-type headache attacks in children with migraine.
Anti-Cytomegalovirus Activity of Sulfated Glucans Generated from a Commercial Preparation of Rice Bran
Authors: Ghosh Tuhin , Auerochs Sabrina , Saha Sudipta , Ray Bimalendu , Marschall Manfred 
Published: November 2010

Background: Many viruses display affinity for polysaccharides presented at the surface of target cells with high biological relevance for virus attachment and entry. This raises the possibility of the application of polysaccharides, particularly their sulfated modifications, in studies of receptor binding and also in antiviral therapy. Methods: In this study, we analysed various sulfated glucans, generated from a commercial preparation of rice bran using chemical, chromatographic, spectroscopic and virological methods. Results: A number of sulfated polysaccharides with different charge densities were generated from a commercial rice bran preparation by aqueous extraction followed by chemical sulfation. The backbone of the type of glucans identified was made up mainly of α-(1→4)-linked glucopyranosyl residues. Sulfate groups were found to be located at C6 and partly at C2 or C3 of glucopyranosyl residues. Sulfation appeared to be very important for anti-cytomegaloviral activity, as desulfation experiments demonstrated an impairment of activity. Using an established cytomegalovirus replication assay with primary human fibroblasts, data demonstrated that the anti-cytomegaloviral effect was determined primarily at the stage of viral entry. Conclusions: Sulfated glucans derived from rice bran possess very promising characteristics for their potential use as entry-inhibiting anti-cytomegaloviral agents.
Ictal very low frequency oscillation in human epilepsy patients
Authors: Ren Liankun , Terada Kiyohito , Baba Koichi , Usui Naotaka , Umeoka Shuichi , Usui Keiko , Matsuda Kazumi , Tottori Takayasu , Nakamura Fumihiro , Mihara Tadahiro , Inoue Yushi 
Published: November 2010

AbstractUsing intracranial electroencephalographic recordings, we identified a distinct brain activity in 3 patients with refractory epilepsy characterized by very early occurrence from 8 minutes 10 seconds to 22 minutes 40 seconds prior to clinical seizure onset, periodical appearance of slow negative baseline shift, long interpeak interval of 40 to 120 seconds, and disappearance after clinical seizure. We named this activity “very low frequency oscillation” (VLFO), which reflected a dynamic process during the preictal state. This observation may render new insight into epileptogenesis and provide additional information concerning the epileptogenic zone as well as prediction of epileptic seizures. Ann Neurol 2010
Study on the damping of EVM based blends
Authors: Shi X. Y. , Weina Bi , Shugao Zhao 
Published: November 2010

AbstractThe mechanical and damping properties of blends of ethylene‐vinyl acetate rubber(VA content >40 wt %) (EVM)/nitrile butadiene rubber (NBR) and EVM/ethylene‐propylene‐diene copolymer (EPDM), both with 1.4 phr BIPB (bis (tert‐butyl peroxy isopropyl) benzene) as curing agent, were investigated by DMA. The effect of polyvinyl chloride (PVC), chlorinated polyvinyl chloride (CPVC), and dicumyl peroxide (DCP) on the damping and mechanical properties of both rubber blends were studied. The results showed that in EVM/EPDM/PVC blends, EPDM was immiscible with EVM and could not expand the damping range of EVM at low temperature. PVC was miscible with EVM and dramatically improved the damping property of EVM at high temperature while keeping good mechanical performance. In EVM/NBR/PVC blends, PVC was partially miscible with EVM/NBR blends and remarkably widened the effective damping temperature range from 41.1°C for EVM/NBR to 62.4°C, while CPVC mixed EVM/NBR blends had an expanded effective damping temperature range of 63.5°C with only one damping peak. Curing agents BIPB and DCP had a similar influence on EVM/EPDM blends. DCP, however, dramatically raised the height of tan δ peak of EVM/NBR = 80/20 and expanded its effective damping temperature range to 64.9°C. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Single center experience with percutaneous endovascular repair of superior vena cava syndrome
Authors: Canales John F. , Cardenas Juan Carlos , Dougherty Kathryn , Krajcer Zvonimir 
Published: November 2010

AbstractObjectives: To demonstrate short‐term effectiveness and long‐term efficacy of percutaneous transluminal angioplasty (PTA) with or without adjunctive therapy in treatment of superior vena cava syndrome (SVCS). Background: Recently, PTA with or without adjunctive therapy has evolved as first‐line therapy for SVCS. Despite growing evidence for PTA with or without adjunctive therapy, there are little data reflecting its short‐ and long‐term outcomes. Methods: We retrospectively reviewed 14 consecutive patients undergoing PTA with or without adjunctive therapy for SVCS, between July 2001 and September 2009. Results: A total of 14 patients (nine women; mean age, 49 ± 15 years) with SVCS underwent attempted PTA with or without adjunctive therapy. Causes of SVCS were indwelling catheters or pacemaker wires (n = 5), idiopathic (n = 5), thoracic outlet syndrome (n = 2), and cancer‐related thrombosis (n = 2). Obstruction of the SVC involved inflow branches in 86% of patients (n = 12). PTA with or without adjunctive therapy was attempted in all 14 patients and was angiographically successful in 93% (n = 13). PTA and stenting was performed in eight (57%) patients; three (21%) patients had PTA with thrombectomy/thrombolysis; one (7%) patient had PTA alone; and one (7%) patient had thrombectomy/thrombolysis alone. Symptom relief was seen in 86% (n = 12), and initial patency was 90%. There were no procedural complications. Mean follow‐up was 12 months, and no deaths were reported. In the 11 (79%) patients with follow‐up imaging, nine (82%) patients showed patency and two (18%) had residual symptoms, with one patient undergoing surgery. Conclusions: PTA with adjunctive endovascular stent therapy for SVCS is safe and effective at giving both rapid and sustained symptom relief. © 2011 Wiley‐Liss, Inc.
Longitudinal oncology registry of head and neck carcinoma (LORHAN)
Authors: Wong Stuart J. , Harari Paul M. , Garden Adam S. , Schwartz Marc , Bellm Lisa , Chen Amy , Curran Walter J. , Murphy Barbara A. , Ang K. Kian 
Published: November 2010

AbstractBACKGROUND:A study was undertaken to examine the patterns of systemic therapy use in conjunction with radiation therapy for patients with locally advanced head and neck squamous cell cancer.METHODS:Between December 1, 2005 and May 11, 2009, 2874 patients with newly diagnosed head and neck squamous cell cancer who were scheduled to receive radiotherapy and/or drug therapy were registered in a prospective national database. The database was specifically analyzed to examine patients who received chemotherapy in conjunction with definitive radiotherapy.RESULTS:A total of 1144 patients received systemic therapy in conjunction with radiotherapy; 645 (56%) patients received agents concurrent with radiation therapy, 49 (4%) patients received chemotherapy before radiotherapy (induction), 224 (20%) patients received chemotherapy before and during radiotherapy (sequential), and 226 (20%) patients received chemoradiation after surgery. Single‐agent cisplatin, single‐agent cetuximab, and carboplatin plus paclitaxel were, in order, the 3 most commonly prescribed concurrent regimens. Concurrent cisplatin was more frequently used in the academic setting compared with the community setting (P = .0015). Postoperative chemoradiation, rather than radiation alone, was more commonly used in academic centers compared with community practice centers (P = <.0001).CONCLUSIONS:The LORHAN (Longitudinal Oncology Registry of Head and Neck Carcinoma) database is a useful barometer of current US practice patterns and can be applied to analyze future trends in the combined modality management of head and neck cancer. Sequential chemotherapy is used frequently, but cisplatin‐based concurrent chemoradiation remains the most commonly used regimen for locally advanced head and neck cancer. Cancer 2011. © 2010 American Cancer Society.
Fine‐needle aspiration of renal and extrarenal rhabdoid tumors
Authors: Thomson Thomas A. , Klijanienko Jerzy , Couturier Jerome , Brisse Herve , Pierron Gaelle , Freneaux Paul , Sastre‐Garau Xavier , Lagace Real , Bourdeaut Franck 
Published: November 2010

AbstractBACKGROUND:Rhabdoid tumors (RT) are rare, renal or extrarenal, high‐grade malignancies. The cytologic diagnosis may be confirmed if combined with genomic results. In the current study, the authors present the cytologic and ancillary techniques used to diagnose RT in their series of 20 tumors in 13 patients.METHODS:Clinical charts as well as cytologic, histologic, karyotypic, and molecular biology results were reviewed.RESULTS:Twelve fine‐needle aspirations (FNAs) were performed for primary diagnosis, 7 were to confirm a metastasis, and 1 was to confirm local recurrence. Primary tumors were in the kidney in 7 cases and 13 were extrarenal. Patient age ranged from 5 months to 26 years. There were 7 females and 6 males. FNAs were cell‐rich in 16 cases and cell‐poor in 4 cases and revealed a mix of atypical spindle‐shaped, round, rhabdoid, or epithelioid cells, singly or in clusters. Mitosis and necrosis occasionally were present. The original cytologic diagnosis was malignant in all cases. There were no unsatisfactory or false‐negative samples. In the 12 primary tumors, the preliminary FNA diagnosis was RT in 7 cases (58%), rhabdomyosarcoma in 4 cases (33%), and malignant peripheral nerve sheath tumor in 1 case (8%). Karyotypes were available in 6 cases, 3 of which demonstrated chromosome 22 changes. Fluorescence in situ hybridization revealed loss of probe signals for the SMARCB1 gene locus in 5 cases; DNA sequence analysis performed in 9 cases revealed deletions in codons of the SMARCB1 gene in 7 cases and a mutation in 2 cases.CONCLUSIONS:The primary diagnosis of RT is possible on FNA. In the current study, 12 of 13 cases were diagnosed by FNA with a combination of clinical information, immunocytochemistry, and molecular analysis. Cancer (Cancer Cytopathol) 2010;. © 2010 American Cancer Society
Technological culture and its interpretation: Research results in Poland
Authors: Wyrwicka Magdalena K. 
Published: November 2010

AbstractImplementation of the same technologies or ideas in production management can lead to different results, even if they are introduced in enterprises functioning in strongly comparable business environments. The anticipated reasons for this phenomenon are varieties in technological culture. Such conjecture was an inspiration to undertake a study in this matter. In this article, a comprehensive analysis of a literature review on culture is presented. It delivers a background of deeper insight into researchers' views of technological culture and its role in implementation of innovations in enterprises. The focus of this article is how employees perceive technological culture and how it can affect implementation of innovations. © 2010 Wiley Periodicals, Inc.