bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sonographic and histopathological findings of endometrium among perimenopausal women with abnormal uterine bleeding- A cross sectional study in north Kerala
Authors: Balathil Ranjana , Shenoy Heera Trivikrama , Mampilly Neena , Ravi Rejeesh Saroja , Vethavayal Rabiyabi , Lakshman Lisha 
Published: May 2024

: AUB makes a perimenopausal woman to seek medical care. This study evaluated and correlated the endometrial thickness obtained by ultrasonography and histopathological findings of endometrium in perimenopausal women with AUB.A hospital based observational cross-sectional study was conducted in Obstetrics and Gynaecology Department, Baby Memorial Hospital, Calicut for a period of 18 months. Histo-pathologic evaluation of endometrial tissue was done and was correlated with endometrial thickness.: The average age of women enrolled was 47.88 years with standard deviation of 3.729. The average endometrial thickness was 12.40mm. Endometrial hyperplasia without atypia was the leading histopathological finding obtained after analysis of endometrium (21.5%). This study shows that there is a significant relationship between histopathology findings of endometrium and age of participant and between endometrial thickness and menorrhagia. There was no relationship between histopathology findings and endometrial thickness. Perimenopausal AUB should be evaluated in a systematic manner, so that endometrial hyperplasia, carcinoma endometrium could be diagnosed in a very early stage and prompt treatment be given at right time reducing morbidity improving the quality of life.
Rural Tourism and Homestays in India: Impact on Local Economy, Culture and Ecology
Authors: Chatterjee Pratim , Chakrabortty Namrata , Ghosh Subho 
Published: May 2024

Purpose of the study: This study explores rural tourism as a sustainable form that encompasses environmental preservation, entrepreneurial opportunities, and the preservation of traditional village customs, values, and practices.
Methodology: The research methodology employed a literature review approach, focusing on secondary data sources. The search utilized the Google Scholar database as a search engine, with the initial 500 results sorted by relevance to ensure comprehensive coverage of relevant scholarly sources. Finally, 31 articles were selected for this study.
Principal Findings: Operating homestays can provide alternative accommodation options and catalyze the promotion of rural tourism, benefiting the local community, economy, and regional art and culture. A well-executed marketing plan in rural tourism can bring significant societal advantages by channeling resources from urban to rural areas and curbing rural-urban migration.
Applications of the study: This study can be helpful in the tourism and hospitality industry. It is instrumental in promoting rural tourism and supplementary accommodation like homestays in India, thus boosting the local economy and promoting local culture and tradition.
Novelty/Originality of the study: Tourism and related industries substantially impact employment due to the sector's labor-intensive nature. Village tourism can generate income and employment and contribute to rural development, preventing rural-urban migration and promoting sustainable revenue generation.
Lipopolysaccharide Stimulation of Peripheral Blood Mononuclear Cells of Indigenous Pigs Causes Enhanced Expression of Pro-inflammatory Cytokines Over Exotic Pigs
Authors: Gali Jagan Mohanarao , Subudhi Prasant Kumar , Behera Parthasarathi , Ali Mohammad Ayub , De Ankan , Jayappa Kiran , Kalita Girin 
Published: May 2024

Background: Selective breeding in pigs based on a higher potential of disease resistance can be achieved by studying the association between immune responsiveness and susceptibility to infectious diseases. The early immune responsiveness of pigs assessed in a quantifiable scale for different determinant cytokine genes’ expression involved in regulation of immune response can be a major determinant for evaluating the immune responsiveness. Methods: In this study, we carried out the quantitative relative expression of candidate cytokine genes [Interleukin-1 beta-(IL1β), IL6, IL10 and tumor necrosis factor-alpha (TNFα) and toll-like receptor-4 (TLR4) gene expression in the lipopolysaccharide (LPS) stimulated peripheral blood mononuclear cells (PBMCs) of Zovawk (indigenous) and Large White Yorkshire (LWY-exotic) pig breeds using real-time PCR to understand the differences in swift immune responsiveness against gram-negative bacteria. Results: Zovawk PBMCs’ pro-inflammatory cytokines IL1β and IL6 expression increased rapidly with LPS stimulation up to 12 h, being significantly higher as early as 4 h compared to that of the LWY PBMCs. In Zovawk pigs, the pro-inflammatory cytokine genes’ expression was found to be quick and high; whereas, in LWY pigs the response was slow and low. Interestingly, the expression of IL10 was not detected in LPS-stimulated PBMCs of Zovawk pigs indicating that the remarkably higher expressions of IL6 and IL1b in response to LPS are within the threshold of the Zovawk pigs which have evolved through generations. Our findings clearly indicate the sturdy and early immune responsiveness of indigenous pigs against gram-negative bacteria over the exotic pigs.
Optimal image 2D/3D by Krawtchouk moments and ABC algorithm
Authors: AAKAM YOUSSEF  , El Ogri Omar , El Mekkaoui Jaouad , Benslimane Mohamed , Hjouji Amal 
Published: May 2024

In our research, we provide an enhanced and effective Krawtchouk moments parameter p optimization approach using the Artificial Bee Colony (ABC) algorithm optimization technique for the purpose of completing tasks including the reconstruction and classification of 3D and 2D images with high quality. The proposed method, which uses the ABC algorithm to generate a suitable parameter based on Krawtchouck moments, aims to accurately characterize the image as a vector known as the descriptor vector of moments, which is then used to reconstruct the image for each order. The simulation and analysis of the findings demonstrate the high level of quality and effectiveness of the suggested KM-ABC approach for image reconstruction, as well as its excellent accuracy in images with and without noise.
Strategi Keluarga Burhanudin Mohamad Diah Dalam Memperkuat Solidaritas Keluarga Di Negara Sosialis, 1959-1962
Authors: Wulandari Ayu 
Published: May 2024

This article discusses the strategy of Burhanuddin Mohamad Diah's family as an ambassador's family in strengthening family solidarity when assigned to two socialist countries, namely Czechoslovakia and Hungary from 1959 to 1962. This article analyzes why family solidarity became so important for their lives in diplomatic posts, the channels and media used to strengthen this solidarity, and the role of women in it. This article was carried out using historical research methods which utilize various primary sources, ranging from ego documents, contemporary publications, oral history, to a number of official archives. This article reveals that family solidarity at diplomatic posts was part of the comfort conditions for the B. M. Diah family. This is due to two factors, namely historical factors and family psychological factors. To build and strengthen family solidarity, the B. M. Diah’s family used a number of channels, spaces, and media, including the family's domestic space, arts, sports, and tourism. This article also reveals that the presence of family solidarity issues has encouraged the emergence of women's agency and activism in the B. M. Diah family. To be precise, B. M. Diah’s wife, Herawati Diah, was present as a driving force, leader, and decision maker in the family in order to strengthen their internal solidarity.
Comparison of Air Contact And Distilled Water Distribution Method in The Conversion of Cao to Ca(OH)2 As A Precursor Hydroxyapatite Synthesis
Authors: Firnanelty Firnanelty , Abubakar Andi Nur Fitriani , Qurniawan Anas , Syam M. A. 
Published: May 2024

<p>Eggshells containing CaCO<sub>3</sub> have potential as bioceramics for several tissue engineering applications. The content of CaCO<sub>3</sub> converted into Ca(OH)<sub>2</sub> can be used as a precursor to implant material. The purpose of the study was to compare two methods of converting CaO into Ca(OH)<sub>2</sub> as the primary material for making hydroxyapatite. The method used is direct contact with air and dissolution with water. Hydroxyapatite synthesis using Ca(OH)<sub>2</sub> is calcined from CaCO<sub>3 </sub>with <em>a sintering</em> temperature of 900 °C. The result of calcination is in the form of CaO. The stages of obtaining Ca(OH)<sub>2</sub> by converting CaO using two methods, namely direct contact with air and dissolution with water. The XRD characterization results obtained that Ca(OH)<sub>2</sub> results from direct contact with air show the formation of phase (<em>portlandite</em>), which is characterized by its presence at the highest typical 2θ angles = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62°. The XRD Ca(OH)<sub>2</sub> pattern with the distilled water distribution process shows the formation of a phase (<em>portlandite</em>) characterized by its presence at angles of 2θ = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62 °. The results of FTIR Ca(OH)<sub>2</sub> characterization of air contact and water dissolution showed strong O-H functional groups at wave numbers 3643 cm<sup>-1</sup> and 3642 cm<sup>-1</sup>, C-O groups at 1487 cm<sup>-1</sup> and 1483 cm<sup>-1</sup>. This suggests that both methods can convert CaO to Ca(OH)<sub>2</sub>, which synthesizes hydroxyapatite. The hydroxyapatite characterization results obtained have met the standard.</p>
Fast-Track Legislation: The Transformation of Law-Making Under Joko Widodo’s Administration
Authors: Huda Ni’matul , Rishan Idul , Pratiwi Dian Kus 
Published: May 2024

<div class="WordSection1"><p>Since the end of 2019, the President and the House of Representatives had performed different legislative functions. Since the Law on the Commission Eradication Commission was amended, legislation had dramatically been transformed. Several laws have been passed and amended quickly. This study discusses three legal issues. <em>First,</em> the conceptual limitation of fast-track legislation in Indonesia. <em>Second</em>, the rationale behind fast-track legislation under Joko Widodo's administration. <em>Third</em>, the impact of fast-track legislation under Joko Widodo's administration. In this <em>socio-legal</em> study, a qualitative analysis is conducted. This study has identified that (1) fast-track legislation in Indonesia can only be adopted through <em>Perpu</em> with all its exemptions and exceptions; (2) the transformation of law-making under Joko Widodo's administration is associated with political pragmatism, political personalization, the elimination of the opposition, and cartel parties; and (3) the transformation of law-making under Joko Widodo's administration is detrimental to the future of Indonesia's democracy. The transformation has degraded the quality of deliberation in law-making. Besides, it does not adhere to law-making procedures, resulting in elitist and conservative laws.<em></em></p></div><p><em><br clear="all" /></em></p>
Word Box Intervention Revolutionizes Early Literacy Potential in Education
Authors: Nikmah Mafrukhatun , Destiana Evie 
Published: May 2024

his study investigates the efficacy of utilizing the "Word Box" media to enhance beginning reading skills among 5-6-year-old children in a preschool setting. Through a classroom action research (PTK) approach involving 12 participants, the study demonstrates a significant improvement in beginning reading proficiency from 17% in the pre-cycle to 83% in cycle II. The findings underscore the effectiveness of the intervention in improving early literacy skills and highlight its implications for teacher pedagogy and classroom management in preschool education.

Highlight:

Notable improvement: "Word Box" enhances beginning reading in preschoolers.
Effective method: Innovative teaching fosters early literacy development.
Pedagogical impact: Improves teacher skills and classroom management in preschool education.

Keyword: Beginning reading, Preschool education, Classroom action research, Word Box media, Literacy development
MUDIG transforms global vocational education by enhancing engagement
Authors: Olvyya Amaydhi , Hasanah Fitria Nur 
Published: May 2024

This research introduces MUDIG (Mobile Understanding Digital Graphic) learning media, designed to enhance class X students' comprehension of Graphic Design at Diponegoro Vocational School, Sidoarjo. Utilizing the Research and Development (R&D) methodology with the Analysis, Design, Development, Implementation, and Evaluation (ADDIE) model, the study aimed to address the lack of engaging learning materials in vocational education. Results from a small-scale trial showed positive student responses, with an average assessment of 86.6%, alongside high suitability ratings from expert validation. Student feedback emphasized increased interest, motivation, and understanding of the subject matter. These findings underscore the potential of innovative media like MUDIG to improve teaching and learning outcomes in vocational education, suggesting avenues for further exploration and implementation in broader classroom contexts.

Highlight:

MUDIG enhances Graphic Design learning in vocational education.
Students respond positively, showing increased interest and comprehension.
R&D methodology, ADDIE model ensure structured development and evaluation.

Keyword: MUDIG, Graphic Design, Vocational Education, R&D Methodology, ADDIE Model
Enhancing Student Collaboration in Science Education Through Outdoor Learning Transformation
Authors: Khoirot Mil’Al , Setiyawati Enik 
Published: May 2024

This study explores the efficacy of implementing outdoor learning to enhance student collaboration in fourth-grade science education at SD Muhammadiyah 1 Candi Sidoarjo, addressing a gap in research regarding its application in primary school science education. Using a descriptive qualitative approach with observation, interviews, and documentation, data analysis followed the Miles and Huberman model. Results indicate successful implementation of outdoor learning, fostering collaboration among students, particularly in accepting responsibility, assisting peers, and respecting opinions. Variations in collaboration effectiveness were noted between student groups. Findings suggest that carefully planned outdoor learning activities can create an engaging learning environment, improving student collaboration and overall learning outcomes in primary school science education.

Highlight:

Outdoor learning in primary science: Enhancing student collaboration and engagement.
Qualitative approach: Investigating student perspectives on outdoor education.
Effective peer interactions: Fostering teamwork in outdoor learning environments.

Keyword: Outdoor learning, Student collaboration, Primary school, Science education, Qualitative research
PENGEMBANGAN BY PRODUCT AYAM MENJADI ABON TIALE BERBAHAN DASAR HATI AYAM DAN IKAN LELE UNTUK MAKANAN TAMBAHAN ANAK BALITA
Authors: Dalimunthe Nathasa Khalida , Saleh Asep Jalaludin , Artika Putri Ayu 
Published: May 2024

Latar Belakang: Makanan tambahan dapat menambah nilai gizi pangan yang akan dikonsumsi anak. Makanan tambahan yang ada dinilai kurang optimal karena sumber bahan dasarnya dari karbohidrat, sedangkan pada anak usia balita mengalami peningkatan kebutuhan akan protein untuk tumbuh kembang. Sumber protein yang memiliki bioavailibilitas yang tinggi berasal dari hewani. Tujuan: Tujuan penelitian untuk mengembangkan produk Abon sebagai makanan tambahan untuk balita berbahan dasar hati ayam dan ikan lele dalam bentuk Abon Tiale. Metode: Desain penelitian adalah experimental murni dengan Rancangan Acak Lengkap (RAL) dua kali pengulangan. Faktor perlakuan dalam pembuatan Abon Tiale yaitu perbandingan hati ayam dan daging ikan lele. Terdapat 4 taraf perlakuan yaitu F1 = 200:0; F2 = 150:50; F3 = 100:100; F4 = 50:150. Uji hedonik digunakan untuk melihat tingkat kesukaan dari 30 panelis semi terlatih terhadap Abon Tiale. Analisis data yang digunakan yaitu deskriptif dan inferensia (One Way ANOVA serta uji Duncan) dengan tingkat kepercayaan 95%. Hasil: Empat formulasi Abon Tiale berbahan dasar hati ayam dan daging ikan lele berbeda pada setiap atribut warna (p=0,000), rasa (p=0,005), aroma (p=0,001), tekstur (p=0,000). Formula terbaik berdasarkan hasil penilaian panelis yaitu formula F3 (50:150). Kesimpulan: Pemanfaatan by product seperti hati ayam berpotensi untuk menjadi makanan tambahan anak balita dalam rangka pencegahan masalah gizi. Penambahan daging ikan lele pada abon dapat meningkatkan daya terima dari sisi warna, aroma, rasa, dan tekstur.
PANGAN FUNGSIONAL MIE CELOR SEBAGAI ALTERNATIF JAJANAN PADAT GIZI UNTUK ANAK USIA SEKOLAH
Authors: Hervidea Radella Hervidea , Dalimunthe Nathasa Khalida 
Published: May 2024

Latar belakang: Anak pada usia sekolah adalah salah satu fase kehidupan yang memerlukan asupan gizi cukup dan seimbang untuk mendukung pertumbuhan, perkembangannya serta beraktivitas fisik. Salah satu upaya yang dapat dilakukan untuk memenuhi kebutuhan gizinya yaitu dengan mengkonsumsi makanan yang bergizi tinggi seperti yang terbuat dari rumput laut jenis Gracillaria sp. dan daun kelor. Pengembangan produk olahan berbahan dasar Gracillaria sp. dan kelor berpotensi dalam meningkatkan kandungan gizi pada jajanan anak sekolah karena memiliki kandungan gizi yang tinggi dan mudah ditemukan. Tujuan: Penelitian ini dianggap penting untuk menemukan formula terbaru dalam menghasilkan pangan fungsional yaitu mie celor (Gracillaria dan kelor) yang tinggi gizi baik makro, mikro dan antioksidan. Metode: Penelitian ini dilaksanakan pada Juni sampai Desember 2023. Pembuatan produk Mie Celor dengan 5 formulasi (F1,F2,F3,F4 dan F5) serta uji organoleptik akan dilaksanakan di Laboratorium Kuliner Universitas Mitra Indonesia dan analisis proksimat, zat gizi mikro dan kandungan antioksidan akan dilaksanakan di Laboratorium Politeknik Negeri Lampung. Data yang dikumpulkan meliputi data yang diuji secara objektif yaitu data uji organoleptik, uji proksimat, zat gizi mikro, dan analisis antioksidan. Uji hipotesis dilakukan menggunakan uji Anova menggunakan program SPSS dengan tingkat signifikansi yaitu p<0.05. Hasil: Berdasarkan hasil uji organoleptik oleh 30 panelis pada penerimaan secara keseluruhan F5 adalah formulasi dengan nilai tertinggi yaitu 3.77 (p-value <0.453). Uji analisis proksimat pada F5 didapatkan hasil kandungan air, abu,protein dan karbohidrat berbeda nyata (p-value <0,05) dibanding dengan F1. Hasil analisis aktivitas antioksidan F5 didapatkan nilai IC50 4534.01 µG/mL. Kesimpulan: Penambahan rumput laut dan kelor meningkatkan nilai penerimaan secara keseluruhan, merubah kadungan air, abu, protein, karbohidrat, lemak dan meningkatkan kandungan antioksidan pada mie celor.
POLA MAKAN DAN AKTIVITAS FISIK MAHASISWA FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS KRISTEN SATYA WACANA SELAMA PANDEMI COVID-19
Authors: Davidson Sarah Melati , Tampubolon Rifatolistia , Situmorang Agnes Rouli 
Published: May 2024

Latar belakang: Pandemi COVID-19 yang terjadi di seluruh dunia membuat kegiatan masyarakat menjadi terbatas karena adanya peraturan yang diterbitkan pemerintah untuk melakukan pembatasan sosial secara besar-besaran. Pembatasan sosial tersebut memberikan dampak pada sistem belajar yang dialihkan menjadi sistem online. Kegiatan-kegiatan mahasiswa yang beralih menjadi onlinedapat berdampak pada pola makan dan aktivitas fisik. Tujuan: untuk mengetahui gambaran pola makan dan aktivitas fisik mahasiswa kesehatan Universitas Kristen Satya Wacana selama pandemi COVID-19. Metode: Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan cross sectional. Data didapatkan dari pengisian kuesioner FFQ dan GPAQ yangdiisi secara mandiri oleh responden. Kuesioner diisi oleh 86 orang responden. Hasil: responden mendapatkan sumber karbohidrat dari nasi dengan frekuensi 17,94 ± 4,12, sumber protein hewani dari daging sapi dengan frekuensi 1,08 ± 0,83, daging ayam dengan frekuensi 6,28 ± 6,22, dan telur ayam dengan frekuensi 4,69 ± 4,65. Konsumsi sayur dan buah-buahan pada mahasiswa cenderung rendah serta konsumsi minuman dan jajanan pada mahasiswa cenderung rendah. Namun, mahasiswa banyak mengonsumsi martabak manis dengan frekuensi 1,21 ± 0,82. Sebanyak 50% mahasiswa kesehatan Universitas Kristen Satya Wacana memiliki aktivitas fisik dengan intensitas rendah dan sebanyak 50 orang responden memiliki kegiatan sedentari kategori tinggi. Simpulan: pola makan mahasiswa kesehatan Universitas Kristen Satya Wacana masih belum sesuai dengan pedoman gizi seimbang dan mengalami penurunan aktivitas fisik.
Antecedent-Focused Emotion Regulation Strategies in Obesity: An EEG study on Distraction and Reappraisal
Authors: Fernandes Joana , Fernandes Carina , Ferreira-Santos Fernando , Torres Sandra 
Published: May 2024

Abstract

Background/ Objectives: Impairments in emotion regulation (ER) have been reported in obesity (OB), with most studies showing greater use of maladaptive strategies while others show difficulties implementing adaptative strategies. A complementary tool to self-report measures for studying ER is event-related potentials (ERP), concretely the late positive potential (LPP), which allows to understand the time-course of ER processes. This study analyzed behavioral and neural correlates of adaptative ER strategies, distraction and reappraisal, and when they start being applied, in OB individuals and healthy controls (HC).
Subjects/ Methods: Twenty-eight participants with OB (BMI > 30) and 23 HC were recruited. Participants performed an ER task, while EEG was recorded.
Results: Results showed that OB individuals (vs. HC) presented greater LPP amplitudes for distraction and reappraisal, at 500-700ms. In the OB group, reappraisal reduced LPP earlier (300-1300ms) than distraction (1500-1700ms).
Conclusions: These findings highlight ER difficulties early in the emotion-generative process in OB, specifically pertaining to attention deployment, independently of the presence of binge eating symptoms.
Advancing Dengue Virus Surveillance: A Rapid Multiplexed One-Step RT-PCR assay for Comprehensive Diagnosis and Serotype Identification
Authors: Gangwar Mayank , Shukla Alka , Singh Digvijay , Singh Ashish , Prakash Pradyot , Nath Gopal 
Published: May 2024

Abstract

Managing dengue effectively is crucial due to four virus serotypes causing varying infection severities. Dengue fever has becoming more prevalent. Cases of haemorrhagic fever place a significant cost on society and its survivors. This study analyses prevalent serotypes during an endemic situation for severity and community transmission.
During a dengue outbreak in 2022, 514 samples were included in this study, and various diagnostic tests were employed. Dengue viral NS1 antigen gene, IgM antibody detection were executed using ELISA tests, while dengue RT-PCR for molecular confirmation using single-tube dengue multiplex RT-PCR assays to detect the presence of viral RNA and determine the infecting serotype. Data suggested that 108 were highly positive for dengue viral NS1Ag. Sensitivity and specificity of single-tube RT-PCR for dengue were found to be 79.41 and 100% respectively. Among the samples tested with the dengue Multiplex Real-Time PCR assay, 50.60% (n=41) were positive with DENV-2 being the most prevalent serotype followed by DENV-1 (32.10%, n=26) and DENV-3 (12.3%, n= 10).
Dengue fever is a global health challenge, especially in India. Serotyping identifies circulating serotypes. RT-PCR multiplexing assay can be a promising molecular diagnostic method, proving highly sensitive, specific, and rapid. It holds great promise for swift and reliable dengue virus detection and serotyping, enhancing future identification of cases for vaccine development.