bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computerized tomography—guided kryorhizotomy in 76 patients with lumbar facet joint syndrome
Authors: Staender Marko , Maerz Ulrich , Tonn Jörg Christian , Steude Ulrich 
Published: May 2009

Object.The authors prospectively evaluated the therapeutic effect of computerized tomography (CT)—guided kryorhizotomy in the treatment of patients with lumbar facet joint syndrome (LFJS) and assessed prognostic factors that predict this effect.Methods.Between February 2001 and March 2004, CT-guided kryorhizotomy of facet joints was performed in 76 patients with LFJS. A diagnosis was established after three positive CT-guided medial nerve branch blocks. Outcome was determined by evaluating the results of a standardized questionnaire, including visual analog scale (VAS) score, use of medication, ability to work, and physical conditions. Measurement was performed before treatment and repeated postoperatively at 3 days, 3 months, and every 6 months thereafter. On September 2004 all patients underwent clinical reevaluation.The median follow-up period was 22.5 months (range 6–43 months); the median interval to pain reduction was 6 months (range 0.1–31 months) after the first kryorhizotomy. The mean VAS pain score was 6.7 preoperatively and 2.9, 3.2, and 3.4 at 3 days, 3 months, and 6 months postoperatively, respectively. In 40% of patients pain was reduced for 12 months or longer. In patients in whom there was no prior surgical treatment of the relevant spinal segment, the duration of pain relief was significantly longer than in patients who had previously undergone surgery (p < 0.03). Eighteen patients underwent a second, seven a third, and one a fourth kryorhizotomy. No patient reported any side effect. The use of CT guidance guarantees an exact needle-tip position control and documentation for repeated procedures.Conclusions.Computerized tomography—guided kryorhizotomy is a minimally invasive and repeatable treatment that yields good long-term results in patients with LFJS.
Biomechanical analysis of a newly designed bioabsorbable anterior cervical plate
Authors: Ames Christopher P. , Acosta Frank L. , Chamberlain Robert H. , Larios Adolfo Espinoza , Crawford Neil R. 
Published: May 2009

Object. The authors present a biomechanical analysis of a newly designed bioabsorbable anterior cervical plate (ACP) for the treatment of one-level cervical degenerative disc disease. They studied anterior cervical discectomy and fusion (ACDF) in a human cadaveric model, comparing the stability of the cervical spine after placement of the bioabsorbable fusion plate, a bioabsorbable mesh, and a more traditional metallic ACP.
Methods. Seven human cadaveric specimens underwent a C6–7 fibular graft—assisted ACDF placement. A one-level resorbable ACP was then placed and secured with bioabsorbable screws. Flexibility testing was performed on both intact and instrumented specimens using a servohydraulic system to create flexion—extension, lateral bending, and axial rotation motions. After data analysis, three parameters were calculated: angular range of motion, lax zone, and stiff zone. The results were compared with those obtained in a previous study of a resorbable fusion mesh and with those acquired using metallic fusion ACPs. For all parameters studied, the resorbable plate consistently conferred greater stability than the resorbable mesh. Moreover, it offered comparable stability with that of metallic fusion ACPs.
Conclusions. Bioabsorbable plates provide better stability than resorbable mesh. Although the results of this study do not necessarily indicate that a resorbable plate confers equivalent stability to a metal plate, the resorbable ACP certainly yielded better results than the resorbable mesh. Bioabsorbable fusion ACPs should therefore be considered as alternatives to metal plates when a graft containment device is required.
Gowers intrasyringal hemorrhage
Authors: Hamlat Abderrahmane , Adn Mahmoudreza , Yahia Mourad Ben , Morandi Xavier , Brassier Gilles , Guegan Yvon 
Published: May 2009

✓ The concept of hemorrhage in a preexisting syringomyelic cavity was first described by Gowers in 1904. Since its first description only 13 cases have been reported. The aims of this report are to describe a new case, bring this entity to wider attention, and summarize the existing literature on the subject.
This 36-year-old woman presented with progressive gait disturbance and unsteadiness. Physical examination revealed incomplete quadriparesis, predominantly on the left side, and hypesthesia below C-7. Magnetic resonance imaging revealed hematomyelia characterized by a heterogeneous hyperintense signal within the central cervical cord. A liquefied well-limited hematoma was evacuated. The postoperative course was uneventful; a near-complete recovery was observed at the 7-year follow-up examination.
Most cases of intrasyringal hemorrhage (ISH) have occurred in syringomyelic cavities associated with scoliosis or Chiari malformation Type I. Although there is no specific clinical picture associated with this entity, it can be characterized by three neurological forms: 1) sudden onset or rapid development of signs and symptoms, 2) acute worsening of symptoms that may improve but leaving greater neurological dysfunction than before the previous episode, and 3) ISH may initiate progressive deterioration in a patient with known syringomyelia.
Intrasyringal bleeding is most probably caused by a sudden dilation of the syringomyelic cavity, which may provoke rupture of the intrasyringal vessels by an acute distension of the accompanying strands.
Magnetic resonance imaging is the most accurate diagnostic modality, and recognition of ISH can lead to early, safe, and efficient surgical treatment.
Spinal hemangioblastoma containing metastatic renal cell carcinoma in von Hippel—Lindau disease
Authors: Altinoz Meric A. , Santaguida Carlo , Guiot Marie-Christine , Del Maestro Rolando F. 
Published: May 2009

✓ The authors describe the case of a patient with von Hippel—Lindau (VHL) disease in which a spinal hemangioblastoma contained metastatic renal cell carcinoma (RCC). The literature on tumor-to-tumor metastasis associated with VHL disease of the central nervous system (CNS) is reviewed.
Midthoracic back pain developed in this 43-year-old man with a left-sided radicular component 2 years after he underwent resection of a left RCC. Radiological findings demonstrated a T6–7 intradural intramedullary lesion. A T5–8 laminectomy and gross-total resection of the spinal cord mass were performed. Light and electron microscopic examination showed features of hemangioblastoma, which contained metastatic foci of RCC. Genetic analysis demonstrated the presence of a deleting mutation in the first exon (nt. 394–406) of the VHL locus, truncating 16 amino acids (N61–77) from the first beta sheet in the VHL protein. A review of the literature revealed that RCC-to-CNS hemangioblastoma is the second most common donor—recipient tumor association among the tumor-to-tumor metastases.
Atlantoaxial Screw Fixation
Authors: Neo Masashi 
Published: May 2009

Object. In this, the first of two articles regarding C1–2 transarticular screw fixation, the authors assessed the rate of fusion, surgery-related complications, and lessons learned after C1–2 transarticular screw fixation in an adult patient series.Methods. The authors retrospectively reviewed 191 consecutive patients (107 women and 84 men; mean age 49.7 years, range 17–90 years) in whom at least one C1–2 transarticular screw was placed. Overall 353 transarticular screws were placed for trauma (85 patients), rheumatoid arthritis (63 patients), congenital anomaly (26 patients), os odontoideum (four patients), neoplasm (eight patients), and chronic cervical instability (five patients). Among these, 67 transarticular screws were placed in 36 patients as part of an occipitocervical construct. Seventeen patients had undergone 24 posterior C1–2 fusion attempts prior to referral. The mean follow-up period was 15.2 months (range 0.1–106.3 months).Fusion was achieved in 98% of cases followed to commencement of fusion or for at least 24 months. The mean duration until fusion was 9.5 months (range 3–48 months). Complications occurred in 32 patients. Most were minor; however, five patients suffered vertebral artery (VA) injury. One bilateral VA injury resulted in patient death. The others did not result in any permanent neurological sequelae.Conclusions. Based on this series, the authors have learned important lessons that can improve outcomes and safety. These include techniques to improve screw-related patient positioning, development of optimal instrumentation, improved screw materials and design, and defining the role for stereotactic navigation. Atlantoaxial transarticular screw fixation is highly effective in achieving fusion, and the complication rate is low when performed by properly trained surgeons.
Rough‐and‐tumble play and the regulation of aggression: an observational study of father–child play dyads
Authors: Flanders Joseph L. , Leo Vanessa , Paquette Daniel , Pihl Robert O. , Séguin Jean R. 
Published: May 2009

AbstractRough‐and‐tumble play (RTP) is a common form of play between fathers and children. It has been suggested that RTP can contribute to the development of selfregulation. This study addressed the hypothesis that the frequency of father–child RTP is related to the frequency of physically aggressive behavior in early childhood. This relationship was expected to be moderated by the dominance relationship between father and son during play. Eighty‐five children between the ages of 2 and 6 years were videotaped during a free‐play session with their fathers in their homes and questionnaire data was collected about father–child RTP frequency during the past year. The play dyads were rated for the degree to which the father dominated play interactions. A significant statistical interaction revealed that RTP frequency was associated with higher levels of physical aggression in children whose fathers were less dominant. These results indicate that RTP is indeed related to physical aggression, though this relationship is moderated by the degree to which the father is a dominant playmate. Aggr. Behav. 35:285–295, 2009. © 2009 Wiley‐Liss, Inc.
Prätubulysin, eine potente und synthetisch leicht zugängliche Vorstufe von Tubulysin aus Angiococcus disciformis
Authors: Ullrich Angelika , Chai Yi , Pistorius Dominik , Elnakady Yasser A. , Herrmann Jennifer E. , Weissmann Kira J. , Kazmaier Uli , Müller Rolf 
Published: May 2009

AbstractEinfacher geht′s auch: Prätubulysin (Formel ohne die grünen Substituenten), ein vereinfachtes Tubulysin, wurde nicht nur im Labor hergestellt, sondern auch in der natürlichen Tubulysinquelle entdeckt. Diese biosynthetische Vorstufe der Tubulysine ist zwar weniger aktiv als die Tubulysine A und D, wirkt aber immer noch im Pikomolbereich auf eine Reihe von Krebszelllinien.magnified image
Triggered Release of an Active Peptide Conjugate from a DNA Device by an Orally Administrable Small Molecule
Authors: Taylor Steven K. , Pei Renjun , Moon Byoung C. , Damera Srikanth , Shen Aihua , Stojanovic Milan N. 
Published: May 2009

AbstractChinin hilft: In einem konzeptionell neuen Ansatz zur gesteuerten Freisetzung wurde das natürliche Insulintagesprofil als Antwort auf drei Mahlzeiten nachgestellt (siehe Graph), indem ein Insulinkonjugat – ausgelöst durch Chinin, einen Bestandteil von Tonic Water – von einer Matrix freigesetzt wurde.magnified image
Using Azobenzene‐Embedded Self‐Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly
Authors: Liu Dingbin , Xie Yunyan , Shao Huawu , Jiang Xingyu 
Published: May 2009

AbstractMal freundlich, mal abweisend: Mithilfe einer gemischten selbstorganisierten Monoschicht aus zweierlei Alkanthiolen – eines mit einer Azobenzoleinheit und einer Peptid‐Endgruppe, das andere mit einer Hexa(ethylenglycol)‐Kette, die eine nichtspezifische Zelladhäsion verhindert – gelang es, die Zelladhäsion photochemisch zu steuern. Beim reversiblen Übergang zwischen E‐ und Z‐konfigurierter Azobenzoleinheit wechselt das Zelladhäsionsverhalten der Oberfläche (siehe Bild).magnified image
A p‐Type NiO‐Based Dye‐Sensitized Solar Cell with an Open‐Circuit Voltage of 0.35 V
Authors: Gibson Elizabeth A. , Smeigh Amanda L. , Le Pleux Loïc , Fortage Jérôme , Boschloo Gerrit , Blart Errol , Pellegrin Yann , Odobel Fabrice , Hagfeldt Anders , Hammarström Leif 
Published: May 2009

AbstractIn tandem: Employing a molecular dyad and a cobalt‐based electrolyte gives a threefold‐increase in open‐circuit voltage (VOC) for a p‐type NiO device (VOC=0.35 V), and a fourfold better energy conversion efficiency. Incorporating these improvements in a TiO2/NiO tandem dye‐sensitized solar cell (TDSC), results in a TDSC with a VOC=0.91 V (see figure; CB=conductance band, VB= valence band).magnified image
Triggered Release of an Active Peptide Conjugate from a DNA Device by an Orally Administrable Small Molecule
Authors: Taylor Steven K. , Pei Renjun , Moon Byoung C. , Damera Srikanth , Shen Aihua , Stojanovic Milan N. 
Published: May 2009

AbstractA real tonic: In a conceptually new approach to controlled release, the natural daily insulin profile in response to three meals is mimicked (see graph) with release of an insulin conjugate from a matrix, triggered by quinine, a component of tonic water.magnified image
Using Azobenzene‐Embedded Self‐Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly
Authors: Liu Dingbin , Xie Yunyan , Shao Huawu , Jiang Xingyu 
Published: May 2009

AbstractA celling point: A mixed self‐assembled monolayer comprising two types of alkanethiols—one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion—enables cell adhesion to be modulated photochemically. The reversible conversion of the azobenzene moiety between E and Z configurations allows the surface to either support or resist cell adhesion.magnified image
Molecular Rods with Oligospiroketal Backbones as Anchors in Biological Membranes
Authors: Müller Peter , Nikolaus Jörg , Schiller Sabine , Herrmann Andreas , Möllnitz Kristian , Czapla Sylvia , Wessig Pablo 
Published: May 2009

AbstractGetting stuck in: A hydrophobic molecular rod with terminal fluorescent moieties has been synthesized. The insertion of the rod into membranes was investigated and shown to incorporate efficiently into model and biological membranes (see picture; gray C, blue N, red O). Those rods can be used as stable membrane‐associated anchors for functionalization of membrane surfaces.magnified image
Processability and mechanical properties for binary blends of PP and LLDPE produced by metallocene catalyst
Authors: Ono Kazuya , Ogita Hiroaki , Okamoto Kenzo , Yamaguchi Masayuki 
Published: May 2009

AbstractProcessability at extrusion coating and mechanical properties of the films obtained are investigated by means of linear and nonlinear rheological measurements and tensile tests for blends of polypropylene (PP) and linear low‐density polyethylene (LLDPE). Both materials are produced by metallocene catalyst. The processability of PP is found to be improved by the addition of LLDPE; the blend shows low level of motor torque and head pressure in an extruder and small level of neck‐in as compared with pure PP. Further, the anisotropy of ultimate tensile strength, which is prominent for PP, is reduced by blending with LLDPE. As a result, the blend having 20 wt % of LLDPE shows appropriate properties in the molten state for extrusion coating and in the solid state as a film. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Modification of poly(vinyl chloride) by IPN formation with poly(ethyl acrylate)
Authors: Chakrabarti Rupa , Chakraborty Debabrata 
Published: May 2009

AbstractSemi‐1 and semi‐2 interpenetrating polymer networks (IPNs) of poly(vinyl chloride) (PVC) and in situ formed poly(ethyl acrylate) (PEA) have been synthesized using diallyl phthalate and ethylene glycol dimethacrylate as the crosslinkers of PVC and PEA, respectively. These two types of IPNs have been compared with respect to their physical, mechanical, and thermal properties and an endeavor has been made to find a correlation of these properties with the morphology generated in these systems. The semi‐1 IPNs displayed a decrease in their tensile strength and modulus while in contrast; the semi‐2 IPNs exhibited a marginal increase with increasing crosslinked PEA incorporation. The semi‐1 and semi‐2 IPNs containing 10 and 30 wt % of PEA displayed a two‐stage degradation typical of PVC in their thermogravimetric and DSC studies while confirming the increased stability of the samples with higher percentages of PEA. The softening characteristics as detected by the extent of penetration of the thermomechanical probe as has been detected by thermomechanical analysis are in conformity with their mechanicals. The biphasic cocontinuous systems as explicit from the morphological studies reveal fibrillar characteristics in both the systems. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Kinetics and mechanism of the radical copolymerization of 4‐vinyl pyridine with methyl acrylate initiated by p‐acetylbenzylidene triphenylarsonium ylide
Authors: Tiwari S. P. , Gehlot C. L. 
Published: May 2009

AbstractThe free‐radical copolymerization of 4‐vinyl pyridine (4‐VP) with methyl acrylate (MA) initiated by p‐acetylbenzylidene triphenylarsonium ylide at 60 ± 0.1°C with dioxane as an inert solvent yielded random copolymers. The kinetic equation was Rp ∝ [Ylide]0.83[4‐VP]0.33 [MA]0.40 (where Rp is the rate of polymerization); in other words, the system followed nonideal kinetics. The values of the energy of activation and kp2/kt (where kp is the rate constant of propagation and kt is the rate constant of termination) were 23.21 kJ/mol and 1.212 × 10−5 mol L−1 s−1, respectively. The reactivity ratios calculated with the Kelen–Tüdos method were 0.14 ± 0.0075 for 4‐VP and 0.56 ± 0.0078 for MA. The copolymers were characterized with Fourier transform infrared, proton nuclear magnetic resonance, differential scanning calorimetry, and electron spin resonance methods. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
The effects of steaming of beech (Fagus orientalis L.) and sapele (Entandrophragma cylindricum) woods on the adhesion strength of varnish
Authors: Kılıç Murat 
Published: May 2009

AbstractIn this study, it was investigated how steaming of beech (Fagus orientalis L.) and sapele (Entandrophragma cylindricum) woods effect the adhesion strength of some varnish types. With this objective, first of all, the surface roughnesses of the steamed and unsteamed specimens having tangential and radial surfaces and prepared from beech and sapele were measured (Kiliç et al., J Mat Proc Tech 2008, 199, 448). Subsequently, cellulosic, polyurethane and water‐based bright varnishes were applied on these surfaces according to the principles stated in ASTM D 4541 and TS EN 24624 and the adhesion strength of the varnished layers were determined. According to the results of the study, the effects of the type of wood, steaming, surface and varnish types were found to be significant in the adhesion strength to the surfaces of the different varnish layers applied to the surfaces of different wooden materials. It was found that beech wood had a higher adhesion strength than sapele wood. The adhesion strength of steamed wooden materials had a lower strength compared with those that were unsteamed. The adhesion strength of specimens with a radial surface were found to be higher than the specimens with tangential surfaces. Whereas, in the varnish types, the highest adhesion strength was obtained with the polyurethane varnish, which completed the chemical reaction on the surfaces of the wooden material. In conclusion, it could be proposed to use beech wood materials having a radial surface in the jobs requiring a high adhesion strength, to sand once again the material due to the increase in roughness of steaming and to use polyurethane varnish. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Nano/micro ternary composites based on PP, nanoclay, and CaCO3
Authors: Sorrentino L. , Berardini F. , Capozzoli M.R. , Amitrano S. , Iannace S. 
Published: May 2009

AbstractNano‐/microcomposites based on polypropylene/montmorillonite/calcium carbonate were prepared by melt mixing. Their structures and properties were characterized by small‐angle X‐ray diffraction, thermal analysis, and rheological measurements. The intercalation degree was found to be dependent on the compatibilizer content and the processing temperature. The addition of the organoclay slightly increased the melt crystallization temperature of polypropylene, acting as nucleating agents, and improved the degree of crystallinity. The rheological tests showed that nanocomposites increased the complex viscosity when compared with the microcomposites with the same filler content and exhibited a pronounced shear‐thinning behavior in the low frequency range. A Carreau‐Yasuda model was used to model the rheological behavior of these materials. The nano‐/microcomposites showed a significant improvement (about 50%) of the Young's modulus when compared with microcomposites with the same filler content due to the intercalation or exfoliation of the organoclay and the enhanced degree of crystallinity. Moreover, some formulations showed an enhancement of elongation at break and ultimate strength. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Membranes of cellulose triacetate produced from sugarcane bagasse cellulose as alternative matrices for doxycycline incorporation
Authors: Rodrigues Filho Guimes , Toledo Leandra Cardoso , Da Silva Leandro Gustavo , De Assunção Rosana Maria Nascimento , Meireles Carla da Silva , Cerqueira Daniel Alves , Ruggiero Reinaldo 
Published: May 2009

AbstractCellulose triacetate (CTA) membranes were prepared using polyethylene glycol, 600 g mol−1, (PEG) as additive and were utilized in essays of doxycycline (DOX) incorporation using two different procedures: (i) incorporation of the drug during the membrane preparation and (ii) incorporation of the drug to a previously prepared membrane. In the first, the produced membrane presented high compatibility between DOX and CTA, what was evidenced by analyzing the DSC curve for a CTA/PEG 50%/DOX system. Results showed that the drug is homogeneously distributed throughout the matrix, molecularly. In the second method, the drug was molecularly and superficially adsorbed, as seen through the DSC curve for the system CTA/PEG 10%/DOX, which nearly does not present alterations in relation to the original material, and through the isotherm of drug adsorption that follows the Langmuir model. Results showed that the membranes produced from sugarcane bagasse are adequate to produce matrices for drug‐controlled release, both for enteric use (Method (i)) and topic use (Method (ii)). © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009