bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal and dielectric properties of the aluminum particle reinforced linear low‐density polyethylene composites
Authors: Zhou Wenying 
Published: January 2011

AbstractThe possibility of obtaining relatively high thermal conductivity and dielectric constant but low dielectric loss polymeric composites by incorporating the core‐shell‐structured aluminum (Al) particles in a linear low‐density polyethylene (LLDPE) by melt mixing and hot pressing was demonstrated in this study. The morphology, thermal and dielectric properties of the composites were characterized using X‐ray diffractions, thermal analysis, scanning electron microscope, and dielectric analyzer. The Al particle decreases the degree of crystallinity and has no appreciable influence on the melting temperature of LLDPE. The thermal conductivity, dielectric constant and loss factor of the composites increase with an increase in Al content at all the frequencies (1 ∼ 106 Hz). The thermal conductivity and dielectric constant of the 70 wt% flaky Al particles filled LLDPE are 1.63 W/mK and 50, much higher than those of the spherical Al reinforced one. Moreover, the surface treatment of Al particles with γ‐Aminopropyltriethoxysilane silane coupler improves the thermal conductivity. The dielectric loss factors of the composites still remain at relatively low levels in the measured frequency range. Further, the dielectric permittivity frequency independence in the measured frequency range was observed due to the nanoscale‐Al‐oxide insulating shell of Al. POLYM. ENG. SCI., 2011. © 2011 Society of Plastics Engineers
A solid homogeneous zirconocene catalyst from Cp2ZrCl2 supported on porous polymer particles
Authors: Lei Jinhua , Li Dongliang , Wang Honghua , Wang Zhuqian , Zhou Guangyuan 
Published: January 2011

AbstractMonodisperse cyano‐functionalized porous polymeric beads were synthesized by seeded polymerization; these microparticles were further used as support for zirconocene catalyst, which performed as a solid homogeneous catalyst in ethylene polymerization. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011
An Examination of Binder Systems and Their Influences on Burn Rates of High‐Nitrogen Containing Formulations
Authors: Sabatini Jesse J. , Freeman Cathleen T. , Poret Jay C. , Nagori Amita V. , Chen Gary 
Published: January 2011

AbstractThe examination of Laminac 4116/Lupersol and Epon 813/Versamid 140 binder systems, and their influences on burn rates of pyrotechnic formulations is described. Laminac 4116/Lupersol‐based formulations had shorter burn times and larger heat of explosion values compared to their Epon 813/Versamid 140 counterparts. An understanding of the chemical structures and approximate oxygen balances of these binder systems served to explain their burn time differences when used in pyrotechnic formulations. Bomb calorimetry of Laminac 4116/Lupersol‐ and Epon 813/Versamid 140‐based formulations provided heat of explosion values to further explain the burn time differences of the two binder systems used.
Robotic‐assisted surgical removal of pelvic schwannoma: a novel approach to a rare variant
Authors: Konstantinidis Konstantinos M. , Hiridis Savvas , Karakitsos Dimitrios 
Published: January 2011

AbstractBackgroundRobotic‐assisted excision of a pelvic schwannoma is presented.MethodsA 27 year‐old female presented with occasional numbness of the right thigh. Imaging studies revealed a large mass adjacent to the right ovary. Robotic surgery with adjunctive electrophysiological monitoring was performed. The mass was adhered to the L4, L5 roots and was displacing the iliac vessels and the ureter. The tumour bulk was decompressed and total excision was facilitated.ResultsPathology revealed a neoplasm consisting of spindle cells. Immunochemistry revealed S‐100+ and a growth index Ki‐67 < 1%. These findings were consistent with the diagnosis of ancient schwannoma. The intraoperative time was comparable to laparoscopy and the patient had an uneventful recovery.ConclusionAncient schwannoma is often diagnosed only when it is large enough to produce symptoms. Robotic surgery with adjunctive electrophysiological monitoring is a safe technique for the removal of large pelvic neurinomas. Copyright © 2011 John Wiley & Sons, Ltd.
Relationship between fetal head station established using an open magnetic resonance imaging scanner and the angle of progression determined by transperineal ultrasound
Authors: Bamberg C. , Scheuermann S. , Slowinski T. , Dückelmann A. M. , Vogt M. , Nguyen‐Dobinsky T. N. , Streitparth F. , Teichgräber U. , Henrich W. , Dudenhausen J. W. , Kalache K. D. 
Published: January 2011

AbstractObjectiveWe investigated the correlation between the angle of progression measured by transperineal ultrasound and fetal head station measured by open magnetic resonance imaging (MRI), the gold standard, in pregnant women at full term.MethodsThirty‐one pregnant women at full term with a fetus in the occipitoanterior position were enrolled. First, the distance between the leading part of the skull and the interspinal plane was obtained using an open MRI system with the patient in a supine position. Immediately after MRI, the angle of progression was obtained by transperineal ultrasound without changing the woman's posture.ResultsThere was a significant correlation between the angle of progression determined by transperineal sonography and the distance between the presenting fetal part and the level of the maternal ischial spines (y = − 0.51x + 60.8, r2 = 0.38, P < 0.001). None of the fetal heads was engaged at the time of MRI and ultrasound examinations.ConclusionsThe present study demonstrated a predictable relationship between the angle of progression obtained by transperineal ultrasound and the traditional scale used to quantify fetal head descent. Based on our results, station 0 would correspond to a 120° angle of progression. However, this correlation is based on statistical assumptions only and has to be proven in future studies. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.
The impact of Alzheimer's disease on the functional connectivity between brain regions underlying pain perception
Authors: Colel Leonie J. , Gavrilescul Maria , Johnstonl Leigh A. , Gibsonl Stephen J. , Farrelll Michael J. , Eganl Gary F. 
Published: January 2011

AbstractPatients with Alzheimer's disease (AD) are administered fewer analgesics and report less clinical pain compared with their cognitively‐intact peers, prompting much speculation about the likely impact of neurodegeneration on pain perception and processing. This study used functional connectivity analysis to examine the impact of AD on the integrated functioning of brain regions mediating the sensory, emotional, and cognitive aspects of pain. Fourteen patients with AD and 15 controls attended two experimental sessions. In an initial psychophysical testing session, a random staircase procedure was used to assess sensitivity to noxious mechanical pressure applied to the thumbnail. In a subsequent brain imaging session, fMRI data were collected as participants received noxious or innocuous thumbnail pressure, delivered at intensities corresponding with previously identified subjective pain thresholds. Two approaches to functional connectivity analysis were utilised. A seed‐based correlation method was first used to identify regions showing significant functional connectivity with the right dorsolateral prefrontal cortex (DLPFC). Functional connectivity between a network of 17 predefined pain processing regions was then assessed. Between‐group comparisons revealed enhanced functional connectivity between the DLPFC and the anterior mid cingulate cortex, periaqueductal grey, thalamus, hypothalamus, and several motor areas in patients with AD compared with control group. Likewise, inter‐regional functional connectivity across most regions of the predefined pain network was shown to be greater in the patient group, with the enhanced functional connectivity centred on three nodes: the DLPFC‐R, hypothalamus, and PAG. The results of this study support previous research suggesting an interplay between pain and cognitive processes in patients with AD.
Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome
Authors: Fouda Usama M. , Sayed Ahmed M. , Abdou Abdel‐Megid A. , Ramadan Dalia I. , Fouda Iman M. , Zaki Mahmoud M. 
Published: January 2011

AbstractObjectiveTo determine whether low molecular weight heparin (LMWH) plus low‐dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS).MethodsIn a randomized prospective study, 60 women with a history of 3 or more consecutive spontaneous abortions and positive antiphospholipid antibodies were assigned in equal numbers to receive either UFH (5000 units, twice daily) plus LDA, or LMWH (enoxaparin 40 mg, once daily) plus LDA as soon as pregnancy was diagnosed.ResultsTwenty‐four women in the LMWH group (80%) and 20 women in the UFH group (66.67%) delivered a viable infant (P = 0.243). There were no significant differences in pregnancy complications or neonatal morbidity between the 2 groups. There were no incidences of excessive bleeding, thrombocytopenia, or osteoporotic fractures in either group.ConclusionLMWH plus LDA was successfully used as an alternative to UFH plus LDA in the management of recurrent abortion secondary to APS. The results highlight the need for a larger randomized controlled trial to determine whether LMWH plus LDA should be the treatment of choice for recurrent abortion secondary to APS.Clinicaltrials.gov NCT01051778.
Bridging the intention–behavior gap: Inducing implementation intentions through persuasive appeals
Authors: Fennis Bob M. , Adriaanse Marieke A. , Stroebe Wolfgang , Pol Bert 
Published: January 2011

AbstractThe potential of using implementation intentions—action plans that link a critical situational cue to a specific goal‐directed behavior—to bridge the intention–behavior gap in consumer behavior has been limited by the practice of using explicit instructions to induce the construct. In two studies, we therefore tested the effectiveness of an indirect, persuasive strategy that benefits from the positive consequences of implementation intentions by ‘mimicking’ their underlying psychological processes. Experiment 1 showed that a strategy presenting vivid information on critical cues and appropriate behavioral responses affected mental imagery. Experiment 2 demonstrated that this strategy affected actual purchase behavior.
Erfolgreiche Rehabilitation bei Menschen mit Migrationshintergrund
Authors: Schott T. , Brause M. , Razum O. , Reutin B. , Yilmaz-Aslan Y. 
Published: January 2011

Einleitung
In Deutschland hat mittlerweile jeder Fünfte der ca. 82 Mio. hier lebenden Personen einen Migrationshintergrund. Bildungsangebote, Gesundheits- und Sozialleistungen und auch die Leistungen der medizinischen Rehabilitation müssen sich diesen Bedingungen anpassen und systematisch hinterfragt werden bezüglich ihrer Angemessenheit und Wirksamkeit bei Menschen mit Migrationshintergrund. In einer durch die Gesellschaft für Rehabilitationswissenschaften NRW geförderten Studie wurde solchen Fragen nachgegangen. Insgesamt zeigte sich für Rehabilitanden mit türkischem Migrationshintergrund ein unterdurchschnittlicher Rehabilitationserfolg, der in erster Linie auf Herkunft, mangelnde Sprachkenntnisse und kulturell bedingte Besonderheiten zurückzuführen ist. Den Einrichtungen der medizinischen Rehabilitation kann im Umgang mit türkischen Rehabilitanden eine Förderung der interkulturellen Kompetenz sowie eine stärkere Patientenorientierung und Individualisierung der Rehakonzepte empfohlen werden.
Feeding sunflower oil to partially defaunate the rumen increases nitrogen retention, urea-nitrogen recycling to the gastrointestinal tract and the anabolic use of recycled urea-nitrogen in growing lambs
Authors: Doranalli Kiran , Mutsvangwa Timothy 
Published: January 2011

The objective of the present study was to delineate how interactions between feeding sunflower oil (SFO) to partially defaunate the rumen and altering dietary ruminally fermentable carbohydrate may alter urea-N kinetics and N metabolism in lambs. In a 4 × 4 Latin square with a 2 × 2 factorial arrangement of treatments, four Suffolk ram lambs (61·5 (se4·0) kg) were used. Treatments were 0 ( − SFO)v.6 % (+SFO) SFO and dry-rolled barley (DRB)v.pelleted barley (PB). N balance was measured over 4 d, with concurrent measurement of urea-N kinetics using continuous intra-jugular infusions of [15N15N]urea. Feeding SFO decreased (P = 0·001) ruminal protozoa and NH3-N concentrations. Urinary N excretion was lower (P = 0·003), and retained N was higher (P = 0·002) in +SFO lambs compared with − SFO lambs. Endogenous production of urea-N (urea-N entry rate; UER) was similar across treatments. Urea-N transfer to the gastrointestinal tract (GIT) (GIT entry rate; GER), expressed as absolute amounts (16·4v.13·1 g/d) or as a proportion of the UER (0·693v.0·570), its anabolic use (9·0v.6·0 g/d) and microbial N supply (14·6v.10·9 g/d) were higher (P ≤ 0·001) in +SFO lambs compared with –SFO lambs. As a proportion of the UER, GER was higher, whereas urinary urea-N loss was lower, in lambs fed PB compared with those fed DRB (P = 0·01). In summary, feeding SFO increased urea-N recycling to the GIT and microbial non-NH3-N supply, thus providing new evidence that the improved efficiency of N utilization in partially defaunated ruminants could be partly mediated by an increase in urea-N recycling.
Differential susceptibility to rearing environment depending on dopamine-related genes: New evidence and a meta-analysis
Authors: Bakermans-Kranenburg Marian J. , van Ijzendoorn Marinus H. 
Published: January 2011

AbstractIn the current paper we present new empirical data and meta-analytic evidence for the role of dopamine-related genes as a susceptibility factor interacting with the rearing environment for better and for worse, that is, increasing children's susceptibility to both the adverse effects of unsupportive environments and the beneficial effects of supportive rearing. In Study 1 we examined the readiness of 91 7-year-old children to donate their money to a charity (UNICEF). We tested whether the association between attachment and donating behavior was moderated by the presence of the dopamine receptor D4 (DRD4) 7-repeat allele. The attachment story completion task was used to assess attachment as an index of the quality of the rearing environment. Children with secure attachment representations donated more but only if they had theDRD47-repeat allele. In Study 2 we present the results of a meta-analysis of gene–environment studies on children up to 10 years of age involving dopamine-related genes (dopamine receptor D2,DRD4, dopamine transporter). The cumulative negative effects of these “risk genes” and adverse rearing environments have been stressed, but potentially cumulative positive effects of these same genes interacting with positive rearing environments remained largely unnoticed. We examined the associations between negativeandpositive rearing environments and developmental outcomes as moderated by dopamine-related gene polymorphisms. Children with the less efficient dopamine-related genes did worse in negative environments than the comparisons without the “genetic risk,” but they also profited most from positive environments. Findings are discussed in light of evolutionary theory, and illustrated with some practical implications of differential susceptibility.
Child and context characteristics in trajectories of physical and relational victimization among early elementary school children
Authors: Giesbrecht Gerald F. , Leadbeater Bonnie J. , Macdonald Stuart W. S. 
Published: January 2011

AbstractTransactional models suggest that peer victimization results from both individual and context differences, and understanding these differences may point to important targets for prevention and interventions that reduce victimization. Multilevel modeling was used to examine within-person (aggression and emotional dysregulation), between-person (sex and age), and between-school (participation in a victimization prevention program) factors that influence changes in physical and relational victimization over the first three years of elementary school. Children (n= 423) reported their experiences of peer victimization at entry into Grade 1 and at the end of Grade 1, Grade 2, and Grade 3. On average, trajectories of both physical and relational victimization declined. However, for individual children, teacher-rated aggression was associated with increases in physical and relational victimization, while emotional dysregulation was associated with attenuation of longitudinal declines in physical victimization and increases in relational victimization. Individual differences in sex and age at entry into Grade 1 did not significantly influence victimization trajectories over Grades 1 to 3. Children who participated in the WITS® victimization prevention program showed significant declines in physical and relational victimization. Levels of victimization among nonparticipants remained stable. Implications of child and context characteristics for preventing peer victimization in elementary school are discussed.
WIST: toolkit for rapid, customized LIMS development
Authors: Huang Y. Wayne , Arkin Adam P. , Chandonia John-Marc 
Published: January 2011

Abstract
Summary: Workflow Information Storage Toolkit (WIST) is a set of application programming interfaces and web applications that allow for the rapid development of customized laboratory information management systems (LIMS). WIST provides common LIMS input components, and allows them to be arranged and configured using a flexible language that specifies each component's visual and semantic characteristics. WIST includes a complete set of web applications for adding, editing and viewing data, as well as a powerful setup tool that can build new LIMS modules by analyzing existing database schema.
Availability and implementation: WIST is implemented in Perl and may be obtained from http://vimss.sf.net under the BSD license.
Contact: jmchandonia@lbl.gov
Supplementary information: Supplementary data are available at Bioinformatics online.
Computational refinement of post-translational modifications predicted from tandem mass spectrometry
Authors: Chung Clement , Liu Jian , Emili Andrew , Frey Brendan J. 
Published: January 2011

AbstractMotivation: A post-translational modification (PTM) is a chemical modification of a protein that occurs naturally. Many of these modifications, such as phosphorylation, are known to play pivotal roles in the regulation of protein function. Henceforth, PTM perturbations have been linked to diverse diseases like Parkinson's, Alzheimer's, diabetes and cancer. To discover PTMs on a genome-wide scale, there is a recent surge of interest in analyzing tandem mass spectrometry data, and several unrestrictive (so-called ‘blind’) PTM search methods have been reported. However, these approaches are subject to noise in mass measurements and in the predicted modification site (amino acid position) within peptides, which can result in false PTM assignments.Results: To address these issues, we devised a machine learning algorithm, PTMClust, that can be applied to the output of blind PTM search methods to improve prediction quality, by suppressing noise in the data and clustering peptides with the same underlying modification to form PTM groups. We show that our technique outperforms two standard clustering algorithms on a simulated dataset. Additionally, we show that our algorithm significantly improves sensitivity and specificity when applied to the output of three different blind PTM search engines, SIMS, InsPecT and MODmap. Additionally, PTMClust markedly outperforms another PTM refinement algorithm, PTMFinder. We demonstrate that our technique is able to reduce false PTM assignments, improve overall detection coverage and facilitate novel PTM discovery, including terminus modifications. We applied our technique to a large-scale yeast MS/MS proteome profiling dataset and found numerous known and novel PTMs. Accurately identifying modifications in protein sequences is a critical first step for PTM profiling, and thus our approach may benefit routine proteomic analysis.Availability: Our algorithm is implemented in Matlab and is freely available for academic use. The software is available online from http://genes.toronto.edu.Supplementary Information: Supplementary data are available at Bioinformatics online.Contact: frey@psi.utoronto.ca
HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens
Authors: Wang Xin , Terfve Camille , Rose John C. , Markowetz Florian 
Published: January 2011

Abstract
Motivation: High-throughput screens (HTS) by RNAi or small molecules are among the most promising tools in functional genomics. They enable researchers to observe detailed reactions to experimental perturbations on a genome-wide scale. While there is a core set of computational approaches used in many publications to analyze these data, a specialized software combining them and making them easily accessible has so far been missing.
Results: Here we describe HTSanalyzeR, a flexible software to build integrated analysis pipelines for HTS data that contains over-representation analysis, gene set enrichment analysis, comparative gene set analysis and rich sub-network identification. HTSanalyzeR interfaces with commonly used pre-processing packages for HTS data and presents its results as HTML pages and network plots.
Availability: Our software is written in the R language and freely available via the Bioconductor project at http://www.bioconductor.org.
Contact: florian.markowetz@cancer.org.uk
Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations
Authors: Tong Mark Y. , Cassa Christopher A. , Kohane Isaac S. 
Published: January 2011

Abstract
Summary: Accurate annotations of genomic variants are necessary to achieve full-genome clinical interpretations that are scientifically sound and medically relevant. Many disease associations, especially those reported before the completion of the HGP, are limited in applicability because of potential inconsistencies with our current standards for genomic coordinates, nomenclature and gene structure. In an effort to validate and link variants from the medical genetics literature to an unambiguous reference for each variant, we developed a software pipeline and reviewed 68 641 single amino acid mutations from Online Mendelian Inheritance in Man (OMIM), Human Gene Mutation Database (HGMD) and dbSNP. The frequency of unresolved mutation annotations varied widely among the databases, ranging from 4 to 23%. A taxonomy of primary causes for unresolved mutations was produced.
Availability: This program is freely available from the web site (http://safegene.hms.harvard.edu/aa2nt/).
Contact: mt153@hms.harvard.edu; mark_tong2009@yahoo.com
Supplementary information: Supplementary data are available at Bioinformatics online.