bluuebunny/crossref_metadata_2025_split huggingface dataset:
Why Some Nonelderly Adult Medicaid Enrollees Appear Ineligible Based on Their Annual Income
Authors: Kim Geena , Minicozzi Alexandra , White Chapin 
Published: June 2024

Abstract
Context: Recent studies have highlighted Medicaid enrollment among middle- and higher-income populations and questioned whether the program is reaching those for whom it is intended.
Methods: The authors use administrative tax data to measure Medicaid enrollment and income in 2017, they use survey data to measure monthly income, and they use administrative data to identify Medicaid enrollment pathways.
Findings: Among 38.8 million nonelderly adults in Medicaid at any point in 2017, 24.4 million had annual income below their state's typical eligibility threshold, and 14.4 million (37%) had income above the threshold. Among those above the threshold, 3.5 million enrolled through a pathway allowing higher income (pregnant women, the “medically needy,” and others). The authors also estimate that more than 12 million had at least one month with income below the threshold, and roughly 4 million had at least five months with income below the eligibility threshold.
Conclusions: Pathways allowing higher income account for one quarter of enrollees with annual incomes above typical thresholds. Among low-income adults, month-to-month variation in income is common and can account for most or all of the remaining enrollees with annual incomes above typical thresholds. A complete accounting of eligibility status would require merged data on income, Medicaid enrollment, and family structure.
On the Simplex Method for 0/1-Polytopes
Authors: Black Alexander E. , De Loera Jesús A. , Kafer Sean , Sanità Laura 
Published: June 2024

We present three new pivot rules for the Simplex method for Linear Programs over 0/1-polytopes. We show that the number of nondegenerate steps taken using these three rules is strongly polynomial, linear in the number of variables, and linear in the dimension. Our bounds on the number of steps are asymptotically optimal on several well-known combinatorial polytopes. Our analysis is based on the geometry of 0/1-polytopes and novel modifications to the classical steepest-edge and shadow-vertex pivot rules. We draw interesting connections between our pivot rules and other well-known algorithms in combinatorial optimization. Funding: A. E. Black and J. A. De Loera are grateful for the support received through the National Science Foundation [Grants DMS-1818969 and NSF GRFP]. L. Sanita is grateful for the support received from the Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Grant VI.Vidi.193.087].
A randomized controlled trial of Golden Ratio, Feng Shui, and evidence based design in healthcare
Authors: Zijlstra Emma , Zwaag Bart van der , Kullak Sabine , Rogers Ab , Walker Dean , van Dellen Sjoukje , Mobach Mark 
Published: June 2024

Background
In a global effort to design better hospital buildings for people and organizations, some design principles are still surrounded by great mystery. The aim of this online study was to compare anxiety in an existing single-bed inpatient hospital room with three redesigns of this room in accordance with the principles of Golden Ratio, Feng Shui, and Evidence-Based Design.

Methods
In this online multi-arm parallel-group randomized trial participants were randomly assigned (1:1:1:1) to one of four conditions, namely Golden Ratio condition, Feng Shui condition, Evidence-Based Design condition, or the control condition. The primary outcomes were anxiety, sense of control, social support, positive distraction, and pleasantness of the room.

Findings
Between June 24, 2022, and August 22, 2022, 558 individuals were randomly assigned to one of the four conditions, 137 participants to the control condition, 138 participants to the Golden Ratio condition, 140 participants to the Feng Shui condition, and 143 participants to the Evidence-Based Design condition. Compared with baseline, participants assigned to the Evidence-Based Design condition experienced less anxiety (mean difference -1.35, 95% CI -2.15 to -0.55, Cohen’s d = 0.40, p < 0.001). Results also showed a significant indirect effect of the Feng Shui condition on anxiety through the pleasantness of the room (B = -0.85, CI = -1.29 to -0.45) and social support (B = -0.33, CI = -0.56 to -0.13). Pleasantness of the room and social support were mediators of change in anxiety in the Evidence-Based Design and Feng Shui conditions. In contrast, application of the design principle Golden Ratio showed no effect on anxiety and remains a myth.

Interpretation
To our knowledge, this is the first randomized controlled trial linking design principles directly to anxiety in hospital rooms. The findings of our study suggest that Feng Shui and Evidence-Based Design hospital rooms can mitigate anxiety by creating a pleasant looking hospital room that fosters access to social support.

Clinical trial registration
The trial is registered with ISRCTN, ISRCTN10480033.
Effect of SCN1Aand SCN2A gene polymorphisms on the efficacy of valproic acid treatment in Chinese children with epilepsy
Authors: Bao Zejun , Li Huanzhou , Hu Jing , Zhao Ru , Yan Ling , Zheng Aibin 
Published: June 2024

Objective
Epilepsy patients exhibit considerable differences in their response to sodium valproate (VPA) therapy, a phenomenon that might be attributed to individual genetic variances. The role of genetic variations, specifically in sodium channels encoded by SCN1A and SCN2A genes, in influencing the effectiveness of VPA in treating epilepsy is still debated. This research focuses on examining the impact of these genetic polymorphisms on the efficacy of VPA therapy among pediatric epilepsy patients in China.

Methods
Five single nucleotide polymorphisms (SNPs), including SCN1A (rs10188577, rs2298771, rs3812718) and SCN2A (rs2304016, rs17183814), were genotyped in 233 epilepsy patients undergoing VPA therapy. The associations between genotypes and the antiepileptic effects of VPA were assessed, with 128 patients categorized as VPA responders and 105 as VPA non-responders.

Results
In the context of VPA monotherapy, SCN1A rs2298771 and SCN2A rs17183814 were found to be significantly associated with VPA response (P< 0.05).

Conclusion
Our study suggests the findings of this investigation indicate that the polymorphisms SCN1A rs2298771 and SCN2A rs17183814 could potentially act as predictive biomarkers for the responsiveness to VPA among Chinese epilepsy patients.
Standing waves for Choquard equation with noncritical rotation
Authors: Mao Yicen , Yang Jie , Su Yu 
Published: June 2024

Abstract
We investigate the existence and stability of standing waves with prescribed mass

c
>
0

c\gt 0

for Choquard equation with noncritical rotation in Bose-Einstein condensation. Then, we consider the mass collapse behavior of standing waves, the ratio of energy to mass and the Lagrange multiplier, as

c
→

0

+

c\to {0}^{+}

. Our results extend the existing results.
Alpha-lipoic acid upregulates the PPARγ/NRF2/GPX4 signal pathway to inhibit ferroptosis in the pathogenesis of unexplained recurrent pregnancy loss
Authors: Zhao Yan , Zhao Xiaoxuan , Feng Xiaoling 
Published: June 2024

Abstract

Aim
With unknown etiology and limited treatment options, unexplained recurrent pregnancy loss (URPL) remains a thorny problem. Ferroptosis, a newly identified type of cell death, has been shown to be crucial in the development in reproductive disorders. This study aims to explore the specific mechanism of ferroptosis in URPL and to uncover whether alpha-lipoic acid (ALA) can inhibit ferroptosis, and then exert a protective effect in URPL.

Method
The decidua tissues of URPL and control patients who actively terminated pregnancy were collected. The CBA/J × DBA/2 murine models of URPL were established, and were randomly treated with peroxisome proliferator activated receptor γ (PPARγ) agonists (Rosiglitazone) and ALA. The CBA/J × BALB/c murine models of normal pregnancy were intraperitoneally injected with PPARγ inhibitors (T0070907). Here, we used reactive oxygen species (ROS), malondialdehyde (MDA), glutathione (GSH)/GSSG, and FeRhoNox-1 analysis to detect the level of ferroptosis. We used quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) analysis to evaluate the mRNA level of PPARγ. Besides, western blot and immunofluorescence were utilized to test the expression profile of PPARγ/nuclear factor erythroid 2-related factor 2 (NRF2)/glutathione peroxidase 4 (GPX4).

Results
In this study, we found that iron deposition was increased in the decidual tissue of patients with URPL. Additionally, the changes in cell morphology, the level of ROS, MDA, GSH, and the expression of ferroptosis marker proteins NRF2/GPX4 confirmed activated ferroptosis in URPL. Besides, bioinformatics analysis combined with experiments confirmed that PPARγ was critical in triggering NRF2/GPX4 pathway in URPL. Furthermore, URPL mouse models were established, and the results showed that PPARγ/NRF2/GPX4-mediated ferroptosis was also significantly increased, which could be mitigated by ALA treatment.

Conclusion
Overall, these findings suggest that ferroptosis may play an important role in URPL, and ALA might be a promising therapeutic drug for improving pregnancy outcomes in URPL via targeting the PPARγ/NRF2/GPX4 pathway.
Characterization of material flow behavior in friction stir welded AA2014 aluminum alloy joints
Authors: Xavier Josephraj Francis , Rajendran Chinnasamy , Sivamaran Venkatesan , Mandal Tapas Kumar 
Published: June 2024

Abstract
Steel rivets serve as a substitute material for connecting similar and dissimilar materials within the structural fabrication industries. However, the use of steel rivets can result in a significant increase in the structure’s weight and may trigger corrosion at the interface due to galvanic coupling. Combining dissimilar alloys through the fusion welding process poses numerous challenges for manufacturers and designers. A solid-state welding technique called friction stir welding (FSW) has been developed. FSW can effectively join materials without reaching their melting points, relying on severe plastic deformation and recrystallization to form a welded joint. The proper selection of the tool and process parameters is essential for achieving a sound weld. The findings of this study indicate that plastic deformation, material flow, and recrystallization play pivotal roles in the strength of the joint. This implies that FSW represents an ideal joining process for high-strength alloys and serves as a viable alternative to replace permanent joints like rivets.
Research on uniaxial compression performance and constitutive relationship of RBP-UHPC after high temperature
Authors: Junjie Zhang , Raza Ali , Weicheng Fu , Chengfang Yuan 
Published: June 2024

Abstract
This study examines the impact of the recycled brick powder (RBP) replacement rate, especially at elevated temperatures on RBP-ultra-high-performance concrete (UHPC) properties such as the stress–strain curve, Poisson’s ratio, elastic modulus, and axial compressive strength through uniaxial compression experiments. The results show that with the increase of heating temperature, the axial compressive strength of the specimen increases first and then decreases under natural cooling (NC). In contrast, Poisson’s ratio shows opposite values. The peak strain continues to increase, and the initial elastic modulus and peak secant modulus continue to decrease. Compared with NC, the axial compressive strength of the specimens under water cooling has been reduced, the peak strain is generally larger, the initial elastic modulus and the peak secant modulus are smaller, and the incorporation of RBP also has a certain effect on the mechanical properties. Through regression analysis, an equation is established to calculate the axial compressive strength of RBP-UHPC with temperature, accounting for variables such as temperature, RBP replacement rate, and cooling method. Furthermore, based on the results of axial compression experiments, a constitutive equation for axial compression in RBP-UHPC after exposure to high temperatures is proposed. Overall, the theoretical curve closely aligns with the experimental curve, verifying its accuracy.
Story of the Wunderkind: An Erlangen Drawing from the Circle of Albrecht Altdorfer
Authors: Guan Luming 
Published: June 2024

Abstract
The depiction of the apocryphal infancy stories of Christ is an important subject in the history of western art, and yet it is rarely investigated. This paper reveals the unidentified subject of an early sixteenth-century drawing at Erlangen by an artist from Albrecht Altdorfer’s circle. It represents the apocryphal stories of Christ gathering pools, animating clay birds, and reviving a fallen child named Zeno. In this paper, the context of this drawing is discussed, along with the history of depicted apocryphal infancy stories in German art and the reception of the Apocrypha in early sixteenth-century Germany around Altdorfer’s circle.
Variability in the Relationship Between Velocity Loss and Percentage of Completed Repetitions During Horizontal Leg Press and Bench Press in Postmenopausal Women
Authors: Iglesias-Soler Eliseo , Rial-Vázquez Jessica , Nine Iván , Fariñas Juan , Revuelta-Lera Borja , García-Ramos Amador 
Published: June 2024

Abstract
Iglesias-Soler, E, Rial-Vázquez, J, Nine, I, Fariñas, J, Revuelta-Lera, B, and García-Ramos, A. Variability in the relationship between velocity loss and percentage of completed repetitions during horizontal leg press and bench press in postmenopausal women. J Strength Cond Res 38(9): 1576–1583, 2024—This study aimed to analyze the intersubject variability in the relationship between percentage of velocity loss (%VL) and percentage of repetitions performed out of maximum possible (%MNR) in postmenopausal women. Thirty-five postmenopausal active women (58 ± 3 years) performed sets leading to muscular failure, completing 10–13 repetitions, in both leg press (LP) and bench press (BP). Mean lift velocity of each repetition was expressed as a percentage of the fastest repetition, and repetitions were quantified as a percentage of the maximum number of repetitions completed in the set. Given the hierarchical structure of the data, %VL–%MNR relationships were fitted by linear mixed model regressions. A significant intersubject variability in the intercept (i.e., %MNR associated with 0%VL) was detected (p < 0.001 in both LP and BP), even when centered values of the completed repetitions were included in the models. The estimated variance in the intercept for LP (117.39; SE: 45.41) was almost double that for BP (67.47; SE: 20.27). The variability observed in the intercept entailed variability in the estimated %MNR for specific %VL values. The use of velocity loss thresholds for estimating the intensity of effort in active postmenopausal women does not overcome uncertainty of more traditional methods.
“Protean Mechanism”: Robert Willis and the Technics of Architectural History
Authors: Crinson Mark 
Published: June 2024

Abstract
Robert Willis’s writing in the nineteenth century was foundational to the development of the discipline of architectural history. Closely related to other Cambridge scientists, including William Farish and William Whewell, Willis deployed similar methods and forms of conceptualization in his writings about medieval architecture. He focused on five areas in particular: the isometric projection, the building as kit-of-parts, detailed technical forms of description using illustrations and specialized vocabularies, the machine tool, and new tools for measuring cogwheels and architectural profiles. Using an interdisciplinary approach and drawing upon contemporary ideas of political economy by Karl Marx and Charles Babbage, this article resituates Willis’s writing in the context of the separation of manual from intellectual labor under industrial capitalism, arguing that the architectural historian was complicit both with the forms of abstraction required of professionalization and with the alienation of labor.
Accelerating Innovation in Primary Care to Support Adolescent Health Discussions
Authors: Jenssen Brian P. , DiFiore Gabrielle , Powell Maura , Luberti Anthony , Rapposelli Angela , Lawton Gregory , Dalembert George , Wood Sarah , Ford Carol A. , Biggs Lisa , Fiks Alexander G. 
Published: June 2024

BACKGROUND AND OBJECTIVES
Adolescent strengths and risks are not routinely captured in systematized and actionable ways in pediatric primary care. To address this problem, we developed a comprehensive adolescent health questionnaire (AHQ) integrated within the electronic health record and evaluated the AHQ’s impact on collection of information on prioritized health-related domains.

METHODS
We developed and pilot tested the AHQ. We then scaled and assessed the AHQ’s impact on data collection. AHQ development used innovation methods and measured feasibility and acceptability outcomes. Scaling and postscaling outcomes included Reach, Effectiveness, Adoption, Implementation, Maintenance and Sustainability measures: Reach (total questionnaires completed), Effectiveness (capture of key information across health domains pre- vs post-AHQ scaling), Adoption (proportion of practices that adopted the AHQ), Implementation (proportion of eligible adolescents who completed the AHQ), and Maintenance (monthly completion rates).

RESULTS
AHQ development led to a tool that was feasible and acceptable for use. During scaling (October 2020–December 2021), 22 147 questionnaires were completed by 20 749 unique adolescents aged 13 to 21 years at their preventive visit. Comparing pre- versus post-AHQ scaling data, use of the AHQ increased collection of information across domains, especially for strengths, gun safety, substance use, sexual activity, sexual orientation, and gender identity, from ranges of 0%–25% to 92%–95%. All 31 practices adopted the AHQ with completion at 88.7% of visits (n = 24 968). Two years postscaling, completion rates were &gt;91% per month.

CONCLUSIONS
We successfully developed, scaled, and maintained an AHQ in a widely-used electronic health record system, a model for improving adolescent care and foundation for developing future interventions.
Mechanochemical depolymerisation, chemical structure, and in vitro prebiotic potential of glucans derived from microcrystalline cellulose
Authors: Yang W.L. , Yu Y. , Sun Y.R. , Ge R.X. , Yin J.W. , Dong Y.B. , Yang Y.Y. , Xu Y.H. , Li Q. , Du W.M. 
Published: June 2024

AbstractConversion of economic microcrystalline cellulose (MCC) into high value-added prebiotic glucans, is not only stimulates utilisation of renewable lignocellulosic biomass, but also provides cheap prebiotics to reduce high incidence of obesity and metabolic syndrome. Herein, glucans (C0.25–C0.50–C1.00) from MCC were prepared by pre-impregnation with dilute sulphuric acid (0.25–0.50–1.00%) and ball-milling treatment for 1 h. NMR spectroscopy and gel-permeation chromatography of the glucan products showed a significant reduction in the degree of polymerisation (DP) and molecular weights (Mw). All prepared glucans improved gut stress evaluated by in vitro digestion and fermentation (young and aging mouse faecal inocula). C1.00 with lower DP and Mw showed better water solubility, earlier peak, and exhibited increased 1-diphenyl-2-picrylhydrazyl activity, higher ratios of Lactobacillus to Escherichia coli, and a higher level of short chain fatty acids better than C0.25 and C0.50 treatment (P < 0.05). Better prebiotic effects were observed in aging mice than in young mice. The highest ratio of Lactobacillus to E. coli was a 2.13-fold increase for aging mice compared to a 1.79-fold increase for young mice, relative to the initial value after C1.00 treatment. The study provides a novel pathway and a new resource for producing glucan.
Brain alterations in individuals with exercise dependence: A multimodal neuroimaging investigation
Authors: Schaub Anna-Chiara , Meyer Maximilian , Tschopp Amos , Wagner Aline , Lang Undine E. , Walter Marc , Colledge Flora , Schmidt André 
Published: June 2024

AbstractBackgroundExercise dependence (ED) is characterised by behavioural and psychological symptoms that resemble those of substance use disorders. However, it remains inconclusive whether ED is accompanied by similar brain alterations as seen in substance use disorders. Therefore, we investigated brain alterations in individuals with ED and inactive control participants.MethodsIn this cross-sectional neuroimaging investigation, 29 individuals with ED as assessed with the Exercise Dependence Scale (EDS) and 28 inactive control participants (max one hour exercising per week) underwent structural and functional resting-state magnetic resonance imaging (MRI). Group differences were explored using voxel-based morphometry and functional connectivity analyses. Analyses were restricted to the striatum, amygdala, and inferior frontal gyrus (IFG). Exploratory analyses tested whether relationships between brain structure and function were differently related to EDS subscales among groups.ResultsNo structural differences were found between the two groups. However, right IFG and bilateral putamen volumes were differently related to the EDS subscales “time” and “tolerance”, respectively, between the two groups. Resting-state functional connectivity was increased from right IFG to right superior parietal lobule in individuals with ED compared to inactive control participants. Furthermore, functional connectivity of the angular gyrus to the left IFG and bilateral caudate showed divergent relationships to the EDS subscale “tolerance” among groups.DiscussionThe findings suggest that ED may be accompanied by alterations in cognition-related brain structures, but also functional changes that may drive compulsive habitual behaviour. Further prospective studies are needed to disentangle beneficial and detrimental brain effects of ED.
Tim Renkow’s <em>Jerk</em>: Cringe Comedy, Disability and Political Correctness
Authors: Sullivan Emma 
Published: June 2024

This paper examines how the British BBC 3 sitcom Jerk (2019–2023) challenges contemporary liberal orthodoxy, mobilising the comic license of its disabled protagonist to interrogate the social prescriptions that breed both hypocrisy and opportunism.
Jerk examines the ways in which the codified structures of ‘correct politics’ can ultimately work against progressive aims: the ‘politics of injury’ defining minority groups by their trauma alone, and identity politics devolving into tribal thinking and niche marketing. Jerk’s plotlines examine howsupposedly reformist positions can reinforce stereotypes, expressive conventions learned by rote can obviate more complex examination of moral questions, and belief in liberal virtue can result in complacency and imperviousness. Jerk’s ‘cringe comedy’ thereby disrupts the piety around liberalpositions, reinforcing the right to challenge and critique.