bluuebunny/crossref_metadata_2025_split huggingface dataset:
Restoration of Vegetation on Fallows in Krasnoyarsk Territory’s Forest Steppes
Authors: Kovaleva N. M. , Sobachkin R. S. 
Published: April 2024

The species richness of the long-fallow lands in the Krasnoyarsk Territory’s forest-steppe zone includes 64 species of vascular plants from 50 genera and 19 families. Leading families of cenoflora are Leguminosae (10 species or 16%), Compositae (10 or 16%), Poaceae (9 or 14%) and Rosaceae (7 or 11%). The basis of the long-fallow lands flora were mesophytes (69%) with an insignificant participation of mesoxerophytes (17%) and mesohygrophytes (9%). Among the ecological-coenotic groups, species of meadow-forest forbs and grasses (34%), ruderal (22%) and forest-steppe (14%) species took the largest part. The aboveground phytomass of the grass cover depended on the age of the fallow (p 0.001) and the density of the pine undergrowth (p 0.05). Forb-brome fallows were the most productive among all in the forest-steppe zone (1.14 ± 0.11–2.02 ± 0.25 t ha–1). Forb-gramineous fallows, experiencing a significant edificatory influence of Scots pine (Pinus sylvestris L.) (density of 29600 units ha–1 in terms of large undergrowth), had the lowest aboveground phytomass (0.23 ± 0.06 t ha–1). Fallow plots aged 7–18 years undergo rapid reforestation, with the density of Scots pine varying widely from 0.9 to 29.6 thousand units ha–1 in terms of large undergrowth. It has been established that with an increase in the Scots pine density, the number of species, species diversity, species saturation, as well as the projective grass cover tend to decrease (p 0.001).
Fronto-Parietal Patterns of Delta and Beta EEG Oscillations as Correlates of the Conditions of Creativity Testing
Authors: Razumnikova O. M. 
Published: April 2024

Recently, much attention has been paid to the mechanism of cooperation between the fronto-parietal system and the default system, since their “pre-tuning” at rest and the subsequent dynamics of functional interaction are associated with an individual variety of strategies for performing tasks while creativity testing. To study the EEG correlates of such strategies, we analyzed the regional specificity of ∆- and β-oscillations in the resting-state and compared them with the results of testing of creativity and intelligence in 37 university students (18 ± 1.1 years; 27 women and 10 men). The indicators of originality of responses when testing creativity were calculated using the databases we created earlier for the subtests “Circles”, “Incomplete figures”, “Unusual use of ordinary objects” and an expert assessment of the originality of sentences made up of words belonging to distant semantic categories. The verbal and figurative components of intelligence were assessed according to the Amthauer intelligence structure subtests. Using the cluster analysis of the listed indicators of creativity and intelligence, we identified two groups of study participants: one (GRKIQ) was characterized by a combination of higher values of intelligence and originality of answers in those tasks where it was required to reject stereotypical ideas while limiting the time for their search, and the other (GRK) – relatively lower intelligence, but high originality of solving the problem in terms of testing creativity with a variety of stimuli and without time limits. These two clusters differed in the regional organization of the power of the ∆- and β2-rhythms and in the correlation patterns of these rhythms: GRKIQ is represented by wide-spread high-frequency β-activity and its correlation with low-frequency biopotentials in the frontal cortex whereas GRK is characterized by cortical mosaic of the β2-activity with its diffusely distributed correlations with the ∆-rhythm by the exception of the anterior frontal areas. The detected effects can be considered as a “pre-tuning” to the strategy of “intelligent” search for an original answer under conditions of resistance to fixation on a stereotyped idea in the GRKIQ or a solution based on a spontaneous search for distant associations in the GRK.
Investigation of the Perception of Three-Dimensional Geometric Figures from the Rotational Movement of Their Two-Dimensional Image in Children with Ophthalmopathology
Authors: Rychkova S. I. , Sandimirov R. I. 
Published: April 2024

Manifestations of the illusion of a three-dimensional structure appearing when rotating a flat projection of a three-dimensional object (structure from motion (SfM)) were studied in three groups of children aged 7 to 17 years: 1) 40 children of the control group with orthotropy, the normal state of visual functions (including binocular and stereovision) and fundus; 2) 33 children with non-paralytic strabismus and normal fundus condition; 3) 50 children with non-paralytic strabismus on the background of congenital partial atrophy of the optic nerve (PAON). As a test image, we used the figure of a hexagon with diagonals passing through its center, presented in binocular and monocular observation conditions in the form of a still image, and when it rotates at a speed of 5, 10, 15, 20, 30, 40 rpm. It was shown that the perception of a three-dimensional structure in the form of a cube is possible with a stationary presentation of a test image in 2–3% of children of both the control group and groups of children with strabismus in binocular and monocular observation conditions. When rotating the test image in both binocular and monocular observation conditions, the number of children who perceived the cube in all groups increased with increasing image rotation speed, reached maximum values at 15–30 rpm and significantly decreased at 40 rpm. In the control group, during the transition from binocular observation conditions to monocular, the number of children perceiving the image as a cube significantly increases at rotational speeds of 5 rpm (p = 0.023), 10 rpm (p = 0.005), 20 rpm (p = 0.002) and 30 rpm (p = 0.001). In groups of children with strabismus (both on the background of normal fundus and on the background of PAON), binocular and monocular indicators were statistically comparable (р 0.05). Comparison of indicators in different groups demonstrated a greater number of children perceiving a three-dimensional figure in the control group than in both groups of children with strabismus at certain speeds of rotation of the test image (from 10 to 20 rpm). In groups of children with strabismus on the background of normal fundus and children with strabismus on the background of PAON, binocular and monocular indicators are statistically comparable for all image rotation speeds. There was no significant dependence of the nature of the perception of the test image on age in all the studied groups of children. Thus, along with the general patterns of SfM manifestations in children of the studied groups, differences were revealed due to the nature of the interaction of monocular and binocular mechanisms of spatial perception in normal and ophthalmopathology. Thus, the SfM study can be used to evaluate the effects of depth and force relations of the monocular and binocular mechanisms of spatial perception in normal and ophthalmopathology.
Taxonomy and Biostratigraphical Significance of the Toarcian Bivalves of the Genus Meleagrinella Whitfield, 1885
Authors: Lutikov O. A. , Arp G. , Захаров В.А. 
Published: April 2024

The morphology of the ligament block and outer parts of the shells of Toarcian bivalves of the genus Meleagrinella (family Oxytomidae Ichikawa, 1958) were studied. The phylogeny of Meleagrinella and Arctotis in the Toarcian was reconstructed on the basis of the conclusions on the evolution of the ontogeny of the ligament pit, made as a result of studying extensive material from Eastern Siberia and Germany, and taking into account the data on the microsculpture of the ostracum. A revision of the species “Monotis” substriata (Münster, 1831), which is widespread in the Toarcian deposits of Europe, Asia, and North America, was carried out. By comparing specimens from different stratigraphic levels of the Lower Toarcian of Eastern Siberia, North-East Russia, and Germany, three species were substantiated: Meleagrinella (Praemeleagrinella?) golberti sp. nov., M. (Clathrolima) substriata (Münster) and M. (Meleagrinella) prima sp. nov. Figures of the ammonite Tiltoniceras sp. ind., Upper Plinsbachian-Toarcian bivalves of the genus Meleagrinella and Upper Toarcian bivalves of the genus Arctotis are given. For the first time, a microsculpture of an ostracum of the Toarcian representatives of the genera Arctotis and Meleagrinella is depicted. In the Upper Pliensbachian–Lower Toarcian, a sequence of oxytomid taxa was established and, based on the Boreal ammonite scale, an assessment of their biostratigraphic significance was given. The sequence is represented by four species: (1) Meleagrinella (Praemeleagrinella) deleta (Upper Pliensbachian), (2) M. (Praemeleagrinella ?) golberti (Tiltoniceras antiquum, Harpoceras falcifer zones), (3) M. (Clathrolima) substriata (Dactylioceras commune Zone), (4) M. (Meleagrinella) prima (Zugodactylites braunianus, Pseudolioceras compactile zones).
Sources of the Paleoproterozoic Terrigenous Rocks of the Nizhnekhani Graben-Sincline, Western Part of the Aldan Shield on the U–Th–Pb (LA-ICP-MS) Geochronological and Nd Isotopic Studies: To the Question of Correlation of the Udokan Complex Deposits
Authors: Kovach V. P. , Adamskaya E. V. , Kotov A. B. , Berezkin B. I. , Timofeev V. F. , Popov N. V. , Plotkina Yu. V. , Skovitina T. M. , Fedoseenko A. M. , Zagornaya N. Yu. , Gorokhovsky B. M. , Кузнецов А.Б. 
Published: April 2024

Paper discusses the results of U–Th–Pb (LA-ICP-MS) geochronological studies of detrital zircon and Sm–Nd isotopic studies of metaterrigenous rocks of the Udokan complex of the Nizhnekhani graben-syncline in the western part of the Aldan Shield. Based on the data obtained, it was found that the accumulation of terrigenous deposits of the Nizhnekhani graben-syncline occurred after 2.65 and up to 1.9 Ga, probably at the Paleoproterozoic stage of the development of the region. The igneous and metamorphic rocks formed at ca. 2.65, 2.71, 2.82–2.86, 2.99, 3.10–3.21, and probably 3.26–3.42 Ga ago within the Chara-Olekma geoblock, the zone of its junction with the West Aldan megablock and the Kurulta block of the Stanovoi suture zone, were the sources of detrital material. Metaterrigenous rocks of the Nizhnekhani graben-syncline were formed from sources with the Paleo- and Mesoarchean Nd model ages, while a significant contribution of the Paleoproterozoic juvenile material was established for the metasedimentary rocks of the Kodar-Udokan trough. Significant differences in the age and Nd isotopic characteristics of terrigenous deposit sources of the Nizhnekhani graben-syncline and the Kodar-Udokan trough suggest that they accumulated in isolated basins.
Resistance of Embryonic Chick Atria to Inhibition of HCN-Channels and Components of the “Ca<sup>2+</sup>-Clock”
Authors: Lebedeva E. A. , Gonotkov M. A. 
Published: April 2024

Despite its medical importance, the cellular mechanisms activity and the contribution of various ion channels of embryonic heart automatism are not yet fully understood. In this study we investigated the effects of specific ion-channel inhibitors on the generation of action potentials in pacemaker cells of the right atrium in chicken embryos (HH36). We used microelectrode technique and evaluated the sensitivity of pacemaker cells to ivabradine (inhibitor of HCN-channels, through which the hyperpolarization-activated current, If), ryanodine (agonist of ryanodine receptors) and SN6 (inhibitor of Na+/Ca2+-exchange). It was found that the right atrium cells have a phase of slow diastolic depolarization. However, these cells were not sensitive to ivabradine (3 μM). We did not register significant changes in the electrophysiological parameters of action potentials.When ryanodine (1 μM) and SN6 (10 μM) were added to the perfusion solution, we observed similar effects: spontaneous rate the generation of action potential increased by 15%. Disturbance of rhythmic activity or disruption of the generation of electrical impulses were not observed in right atrial samples of chicken embryos. The obtained results allow us to conclude that, at this of embryonic development stage, HCN4-channels, ryanodine receptors, and the Na+/Ca2+-exchange are not decisive for maintaining the automatism of the right atrial cells in the chick embryo. We assume that the ion currents flowing through these channels are important in electrophysiology in adult animals, but they have a modulating function in the embryonic myocardium.
Displaced materials of German origin in Tomsk State University Library
Authors: Portnykh V. L. 
Published: April 2024

The article explores available data on displaced materials from Germany in the Research Library of Tomsk State University (TSU), one of the largest academic libraries in Russia. It provides a summary on where and how German books were transported to TSU. The paper also explores what do they represent and where they originate from. Among other sources, the author uses unpublished documents related to negotiations between Russia and Germany on the displaced art in the 1990s. He concludes that the materials mostly have library provenance and arrived to the USSR by train No. 176/8037 Berlin – Leningrad in August 1946. Most probably, the library materials were delivered from Leningrad to Moscow, and later, in 1980, from Moscow to Tomsk. Most of the books belonged to the libraries of Magdeburg, Bremen and Berlin. Some part of the Tomsk collection might have been transported by another train from Berlin to Moscow. However, since these books were stored at the same storage facility at Berlin-Rummelsburg station as those dispatched to Leningrad, we might admit some sorting mistakes. Relatively modern printed books make the core of the collection though there is a small number of medieval manuscripts and archival documents. Possibly, the latter ended up in Tomsk by accident.The article is prepared in the State Public Library of Scientific Technological Library of the Siberian Branch of the of the Russian Academy of Sciences, project No. 122041100088-9 “Transformation of the book culture in the social communications in the 19th-21st centuries”.
Not to throw the baby out with the bath water… On the approach to assessing research output
Authors: Beskaravainaya E. V. 
Published: April 2024

The need for evaluating scientific research demands adjusting methodology. Today, the two existing approaches, namely bibliometrical analysis and expert opinion, will not meet the demands of researchers and administrators if used separately. Based on the reviews, reports and personal practical experience, the author examines the pros and cons of these two approaches and concludes on the need to integrate them so they complement one another. The bibliometrical studies related to scholarly publications processing and quantitative analysis enable to identify the most globally important works while the expert opinion enables to distinguish radically new themes at the early stage.The author argues that the methodology of three components will be the most efficient for science advance; they are: bibliometrical analysis, expert review, and opinion of the professional who would browse the publications in his/her specialty searching for promising themes. Properly synchronized, these three approaches would enable to make economically efficient and informative foundation for rating research activities and to identify the newest vectors in science at the early stage of their emergence.
El El diálogo entre las comunidades locales y los procesos de conservación-restauración de bienes culturales. Nuevas perspectivas y desafíos.
Authors: Calvo Bayo Isabel 
Published: April 2024

El diálogo entre las comunidades locales y los procesos de conservación y restauración del patrimonio es esencial para una gestión cultural eficaz y sostenible. Este intercambio facilita una comprensión más profunda de las necesidades, valores y preocupaciones de las comunidades locales con el patrimonio cultural. Al involucrar a todas las partes interesadas en el proceso de toma de decisiones, se fomenta un mayor sentido de pertenencia y responsabilidad compartida.
Establecer este diálogo puede tener un impacto positivo significativo en la identidad cultural, el desarrollo sostenible y la cohesión social de las comunidades, fortaleciendo así su conexión con su entorno y contribuyendo al enriquecimiento del patrimonio cultural. Además, este enfoque abre nuevas perspectivas y desafíos para desarrollar estrategias que reflejen las necesidades y valores de las comunidades locales, garantizando así la preservación y valorización del patrimonio cultural para las generaciones futuras.
patrimonio, sociedad, restauración, conservación, diálogo, oportunidad
Development and validation of the chromatography-mass spectrometry technique for polyprenols quantitative assessment
Authors: Popov N. S. , Antipina A. A. , Savintsev S. V. , Balabanyan V. Y. 
Published: April 2024

Introduction. Polyprenols are known as a class of natural long-chain isoprenoid alcohols, which are natural bioregulators that directly participate in the synthesis of cell membrane glycoproteins. Their hepatoprotective activity is proven, as well other types of their pharmacological effects are known, which is the reason of significant interest in these substances as a promising medicinal product. It is non-trivial task to determine the sum of polyprenols in extracts as include design and implementation of accurate reproducible analytical methods, which will subsequently be used in standardization.Aim. Development and validation of the chromatographic-mass spectrometric technique for polyprenols identification and their quantitative assessment.Materials and methods. Chromatographic separation of polyprenols was performed by using an HPLC Agilent 1260 Infinity II (Agilent Technologies, США); with the mixture of methanol, n-hexane, propanol-2, and aqueous ammonium acetate solution as eluent in gradient mode. An AB Sciex QTrap® 3200MD (AB Sciex Pte. Ltd., Singapore) triple quadrupole mass spectrometer was used as a detector, with the registration of polyprenols adducts.Results and discussion. The conditions for chromatographic separation and detection of polyprenols were identified. The developed technique was validated for the following characteristics: specificity, limit of detection, limit of quantification, linearity, accuracy, precision, range of application, and stability.Conclusion. It was determined the content of polyprenols in the substance recieved from Ginkgo biloba L. and Picea abies L. The developed technique can be used in the future to assess the content of polyprenols in drug products or pharmaceutical substances.
Heart failure and economic impact: an analysis in real clinical practice in Italy
Authors: Dovizio Melania , Leogrande Melania , Degli Esposti Luca 
Published: April 2024

Introduction: Heart failure (HF) affects 1% of subjects aged 45-55 and over 10% of subjects aged ≥ 80 and in Italy represents the third leading cause of hospitalization.
Objective: To analyse the clinical and economic burden of HF in the Italian real clinical practice.
Methods: A retrospective analysis was conducted on the administrative databases of healthcare institutions for 4.2 million health-assisted residents. Between January 2012 and March 2021, patients with a hospital discharge diagnosis for HF were included. Among healthcare utilization and costs, treatments, hospitalizations, and specialist services were evaluated. The HF group was compared with a population without HF (no-HF) similar for age, sex distribution, and cardiovascular risk factors.
Results: The same number of patients with (N = 74,085) and without HF (N = 74,085) was included. A profile of cardiovascular comorbidities emerged in the HF group, mainly hypertension (88.6%), cardiovascular disease (61.3%) and diabetes (32.1%). Hospitalizations from any cause were 635.6 vs 429.8/1,000 person-year in the HF vs no-HF group. At one-year follow-up, all-cause mortality was 24.9% in HF patients and 8.4% in no-HF. Resource utilization/patient was respectively 26.8 ± 15.9 vs 17.1 ± 12.5 for medications, 0.8 ± 1.2 vs 0.3 ± 0.8 for hospitalizations, and 9.4 ± 12.6 vs 6.5 ± 9.8 for specialist services. This resource utilization resulted in significantly higher total healthcare costs in the HF group vs no-HF group (€ 5,910 vs € 3,574, p < 0.001), mainly related to hospitalizations (€ 3,702 vs € 1,958).
Conclusions: HF patients show a significantly higher clinical and economic burden than no-HF, with total healthcare costs being about 1.7 times the costs of the no-HF group.
Keywords: Cardiovascular comorbidities, Healthcare costs, Heart failure, Hospitalizations
Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways
Authors: Ma Run , Xie Na , Shu Yuanhui , Wu Yafeng , He Ping , Xiang Yining , Zhou Yan , Wang Yuping 
Published: April 2024

Liver fibrosis has become a serious public health problem that can develop into liver cirrhosis and hepatocellular carcinoma and even lead to death. Cannabidiol (CBD), which is an abundant nonpsychoactive component in the cannabis plant, exerts cytoprotective effects in many diseases and under pathological conditions. In our previous studies, CBD significantly attenuated liver injury induced by chronic and binge alcohol in a mouse model and oxidative bursts in human neutrophils. However, the effects of CBD on liver fibrosis and the underlying mechanisms still need to be further explored. A mouse liver fibrosis model was induced by carbon tetrachloride (CCl4) for 10 weeks and used to explore the protective properties of CBD and related molecular mechanisms. After the injection protocol, serum samples and livers were used for molecular biology, biochemical and pathological analyses. The results showed that CBD could effectively improve liver function and reduce liver damage and liver fibrosis progression in mice; the expression levels of transaminase and fibrotic markers were reduced, and histopathological characteristics were improved. Moreover, CBD inhibited the levels of inflammatory cytokines and reduced the protein expression levels of p-NF-κB, NF-κB, p-IκBα, p-p38 MAPK, and COX-2 but increased the expression level of PPAR-α. We found that CBD-mediated protection involves inhibiting NF-κB and activating PPAR-α. In conclusion, these results suggest that the hepatoprotective effects of CBD may be due to suppressing the inflammatory response in CCl4-induced mice and that the NF-κB and PPAR-α signaling pathways might be involved in this process.