bluuebunny/crossref_metadata_2025_split huggingface dataset:
Z2classification of FTR symmetric differential operators and obstruction to Anderson localization
Authors: Bal Guillaume , Wang Zhongjian 
Published: June 2024

AbstractThis paper concerns theZ2classification of Fermionic Time-Reversal (FTR) symmetric partial differential Hamiltonians on the Euclidean plane. We consider the setting of two insulators separated by an interface. Hamiltonians that are invariant with respect to spatial translations along the interface are classified into two categories depending on whether they may or may not be gapped by continuous deformations. Introducing a related odd-symmetric Fredholm operator, we show that the classification is stable against FTR-symmetric perturbations. The property that non-trivial Hamiltonians cannot be gapped may be interpreted as a topological obstruction to Anderson localization: no matter how much (spatially compactly supported) perturbations are present in the system, a certain amount of transmission in both directions is guaranteed in the nontrivial phase. We present a scattering theory for such systems and show numerically that transmission is indeed guaranteed in the presence of FTR-symmetric perturbations while it no longer is for non-symmetric fluctuations.
Quantum Fisher information power of quantum evolutions
Authors: Zhao Jun-Long , Zhou Yan-Hui , Chen Dong-Xu , Su Qi-Ping , Zong Xiao-Lan , Wu Qi-Cheng , Yang Ming , Yang Chui-Ping 
Published: June 2024

Abstract
Quantum metrology is an important field in quantum information and plays a crucial role in quantum parameter estimation. Quantum Fisher information (QFI) is widely used to characterize the precision of quantum parameter estimation. However, a full understanding of the precision for different parameterization processes and the role of quantum evolutions in quantum parameter estimations, remains a crucial area of research. In this paper, we introduce a new concept, named as quantum Fisher information power (QFI power), to characterize the QFI-creating capability of quantum evolutions. At the same time, we take both unitary and non-unitary evolutions as examples and study QFI power. The results show that: (i) For unitary evolutions described by spin angular momentum operators, the dynamic of QFI power is dependent on the z component of the Bloch vector, and the rotating angle; (ii) For non-unitary evolutions under decoherence channels, QFI cannot be enhanced when the initial probe state belongs to zero QFI set, and the QFI power is negative when the initial probe state has maximal QFI; (iii) For the

PT

- and

APT

-symmetric non-unitary evolutions, the dynamics of QFI power exhibit oscillations in symmetry unbroken regime, while the phenomenon of stable value (SV) occurs in broken regimes with the SV = 1.
On positively divisible non-Markovian processes
Authors: Canturk Bilal , Breuer Heinz-Peter 
Published: June 2024

Abstract
There are some positively divisible non-Markovian processes whose transition matrices satisfy the Chapman–Kolmogorov equation. These processes should also satisfy the Kolmogorov consistency conditions, an essential requirement for a process to be classified as a stochastic process. Combining the Kolmogorov consistency conditions with the Chapman–Kolmogorov equation, we derive a necessary condition for positively divisible stochastic processes on a finite sample space. This necessary condition enables a systematic approach to the manipulation of certain Markov processes in order to obtain a positively divisible non-Markovian process. We illustrate this idea by an example and, in addition, analyze a classic example given by Feller in the light of our approach.
Simultaneous clustering and estimation of networks in multiple graphical models
Authors: Li Gen , Wang Miaoyan 
Published: June 2024

Summary
Gaussian graphical models are widely used to study the dependence structure among variables. When samples are obtained from multiple conditions or populations, joint analysis of multiple graphical models are desired due to their capacity to borrow strength across populations. Nonetheless, existing methods often overlook the varying levels of similarity between populations, leading to unsatisfactory results. Moreover, in many applications, learning the population-level clustering structure itself is of particular interest. In this article, we develop a novel method, called Simultaneous Clustering and Estimation of Networks via Tensor decomposition (SCENT), that simultaneously clusters and estimates graphical models from multiple populations. Precision matrices from different populations are uniquely organized as a three-way tensor array, and a low-rank sparse model is proposed for joint population clustering and network estimation. We develop a penalized likelihood method and an augmented Lagrangian algorithm for model fitting. We also establish the clustering accuracy and norm consistency of the estimated precision matrices. We demonstrate the efficacy of the proposed method with comprehensive simulation studies. The application to the Genotype-Tissue Expression multi-tissue gene expression data provides important insights into tissue clustering and gene coexpression patterns in multiple brain tissues.
Preventing New Gram-negative Resistance Through Beta-lactam De-escalation in Hospitalized Patients With Sepsis: A Retrospective Cohort Study
Authors: Teshome Besu F , Park Taehwan , Arackal Joel , Hampton Nicholas , Kollef Marin H , Micek Scott T 
Published: June 2024

Abstract

Background
Whether antibiotic de-escalation reduces the risk of subsequent antibiotic resistance is uncertain. We sought to determine if beta-lactam (BL) antibiotic de-escalation is associated with decreased incidence of new Gram-negative resistance in hospitalized patients with sepsis.

Methods
In a retrospective cohort study, patients with sepsis who were treated with at least 3 consecutive days of BL antibiotics, the first 2 days of which were with a broad-spectrum BL agent defined as a spectrum score (SS) of ≥7 were enrolled. Patients were grouped into three categories: (1) de-escalation of beta-lactam spectrum score (BLSS), (2) no change in BLSS, or (3) escalation of BLSS. The primary outcome was the isolation of a new drug-resistant Gram-negative bacteria from a clinical culture within 60 days of cohort entry. Fine-Gray proportional hazards regression modeling while accounting for in-hospital death as a competing risk was performed.

Findings
Six hundred forty-four patients of 7742 (8.3%) patients developed new gram-negative resistance. The mean time to resistance was 23.7 days yielding an incidence rate of 1.85 (95% confidence interval [CI]: 1.71–2.00) per 1000 patient-days. The lowest incidence rate was observed in the de-escalated group 1.42 (95% CI: 1.16–1.68) per 1000 patient-days. Statistically significant reductions in the development of new gram-negative resistance were associated with BL de-escalation compared to no-change (hazards ratio (HR) 0.59 [95% CI: .48–.73]).

Conclusions
De-escalation was associated with a decreased risk of new resistance development compared to no change. This represents the largest study to date showing the utility of de-escalation in the prevention of antimicrobial resistance.
A Relational Analysis of Exceptionalism: Connecting Liberalism with Confucian Multilateralism and Emotion
Authors: Shih Chih-yu , Kuo Jason 
Published: June 2024

Abstract
The literature on exceptionalism is preoccupied with its distinctive national sources and resultantly differing styles. Exceptionalism has thus become almost synonymous with culture and identity, rather than international relations (IRs). The paper instead argues that exceptionalism reveals a relational identity that both informs and is informed by a multilateral relation prior to the emergence of exceptionalism. It also argues that all relational systems seek expansion and coexistence. Based upon a comparative study of Confucian and liberal multilateral relationalities, a similar cycle of engagement, conversion, disengagement, and learning is applicable to both. Two exceptionalisms in multilateral relationality differ, however. American exceptionalism embraces a transcendent identity with which to contrast with the rest, who share the same identity and are expected to follow the same rules. Chinese exceptionalism contrarily envisions a superior, benevolent identity to ensure harmony and peace among all, who share no collective identity. The paper traces how Confucianism diverges from liberalism with regard to what accounts for multilateralism—inclusiveness versus rule-based governance, and benevolent exceptions versus universal rights—and the resulting orientations during encounters with strangers. The last section before the conclusion corresponds to the growing attention in IRs theorising to the factor of emotion. Such rational–emotional connectivity—between exceptionalism and emotion—can further attest to the promise of the relational agenda in explaining pluriversal IRs.
COMPARATIVE STUDIES ON S-GLYCOPROTEINS PURIFIED FROM DIFFERENT S-GENOTYPES IN SELF-INCOMPATIBLE BRASSICA SPECIES II. IMMUNOLOGICAL SPECIFICITIES
Authors: Hinata Kokichi , Nishio Takeshi , Kimura Jun 
Published: June 2024

ABSTRACT
Antisera were prepared by immunization of apparently purified S-glycoproteins; one from an S allele of Brassica campestris and two from S alleles of B. oleracea. Each antiserum was reactive not only with the homologous S-glycoprotein but also with the heterologous ones, i.e. with the S-glycoproteins of the other S alleles of the same locus. In double diffusion tests, a spur against the heterologous S-glycoproteins suggested heterogeneity of the glycoproteins. The heterogeneity appears to involve a component of the molecule in which the genotypic specificity of an S-glycoprotein resides, probably, for the recognition site. Some molecular components are common to all tested S-glycoproteins and in this respect are like the public antigens of the MHC locus of mammals. The common molecular components were recognized between the S-allele-specific glycoproteins within B. oleracea and also between them and those of B. campestris. No S-specific substances were detected in buffer soluble homogenates of style, ovary or anther. However, these homogenates contained substances that had structures similar to the corresponding common parts of the S-glycoproteins.
TOPOISOMERASE INVOLVEMENT IN MULTIPLICITY REACTIVATION OF PHAGE T4
Authors: Miskimins Robin , Schneider Silke , Johns Virginia , Bernstein Harris 
Published: June 2024

ABSTRACT
The products of phage T4 genes 39, 52 and probably 60 have been previously characterized as forming a type II DNA topoisomerase. Other evidence suggested that this topoisomerase promotes normal initiation of DNA replication, and that when it is defective its loss is partially compensated for by the host gyrase. We present evidence here that mutants defective in genes 39, 52 and 60 have reduced ability to carry out multiplicity reactivation (MR, a form of recombinational repair) of phage DNA damaged either by mitomycin C (MMC) or psoralen plus near-UV light (PUVA). We also observed that there is not extensive superhelicity in the intracellular phage DNA either in the presence or absence of the phage topoisomerase. This tends to rule out the possibility that the topoisomerase influences MR by controlling the general superhelicity of the phage DNA. The dependence of MR on topoisomerase could occur in several possible ways. However, we favor the explanation that the lesions are bypassed by a postreplication recombinational repair process that is influenced by the topoisomerase through its role in initiating replication.
SEPARATION OF LINKED MARKERS IN CHINESE HAMSTER CELL HYBRIDS: MITOTIC RECOMBINATION IS NOT INVOLVED
Authors: Rosenstraus Maurice J , Chasin Lawrence A 
Published: June 2024

ABSTRACT
A search for mitotic recombination was carried out using mutant subclones of cultured Chinese hamster ovary cells. Recombination events were sought between the linked loci specifying the enzymes hypoxanthine phosphoribosyl tranferase and glucose-6-phosphate dehydrogenase. It was shown by fluctuation analysis that markers at these two loci co-segregate from doubly heterozygous pseudotetraploid hybrid cells more than 90% of the time. The minority class of segregants, which had lost one marker without losing the other, were genetically analyzed to distinguish between the possibilities of mitotic recombination and deletion of chromosomal material. Nine clones in which a linkage disruption had occurred were studied, using further cell hybridization and segregation. In three cases, a recessive lethal loss of genetic information was indicated, suggesting the deletion mechanism. In six cases, it was demonstrated that no new linkage relationships had been established concomitant with linkage disruption. Thus, in all nine clones, the evidence indicated that mitotic recombination was not involved in the events that disrupted linkage between these two loci. If mitotic recombination takes place at all in this system, the rate must be less than about 10−6 per cell per generation.
Virtual Group Cognitive Stimulation Therapy for Dementia: Mixed-Methods Feasibility Randomized Controlled Trial
Authors: Spector Aimee , Abdul Wahab Nur Diyanah , Stott Joshua , Fisher Emily , Hui Esther K , Perkins Luke , Leung Wing Gi , Evans Rachel , Wong Gloria , Felstead Cerne 
Published: June 2024

Abstract

Background and Objectives
Cognitive stimulation therapy (CST) is an evidence-based group intervention for people with dementia, with benefits for cognition and quality of life when delivered face-to-face. Many people are unable to attend face-to-face groups for reasons including health and transport issues. This study aimed to assess the feasibility and acceptability of online or “virtual” CST (vCST).

Research Design and Methods
Single-blind, randomized controlled feasibility design with qualitative interviews. Forty-six people with mild-to-moderate dementia were randomly allocated to attend either 14 sessions of twice-weekly vCST (n = 24) or treatment as usual (TAU, defined as usual care; n = 22) over 7 weeks. Cognition, quality of life, and depression were assessed pre- and posttreatment. Qualitative interviews (n = 16) with participants and carers were analyzed using thematic analysis.

Results
High levels of attendance, adherence, fidelity to the manual, and completion of outcomes were recorded. Recruitment appeared feasible although randomization may not have been acceptable to some. There were no statistical differences noted between vCST and TAU in any of the outcomes evaluated, although both quantitative and qualitative data indicated acceptability, with qualitative reports of improved outcomes including cognition.

Discussion and Implications
vCST appeared feasible to deliver but did not result in any changes in outcomes, as expected from an underpowered feasibility trial. CST is the main psychosocial intervention delivered for dementia in UK memory services and globally, with many services moving towards virtual CST delivery. Therefore, a fully powered RCT of the effectiveness of vCST is feasible and justified.
Temporal trends in disparities in COVID-19 seropositivity among Canadian blood donors
Authors: Yu Yuan , Knight Matthew J , Gibson Diana , O’Brien Sheila F , Buckeridge David L , Russell W Alton 
Published: June 2024

Abstract

Background
In Canada’s largest COVID-19 serological study, SARS-CoV-2 antibodies in blood donors have been monitored since 2020. No study has analysed changes in the association between anti-N seropositivity (a marker of recent infection) and geographic and sociodemographic characteristics over the pandemic.

Methods
Using Bayesian multi-level models with spatial effects at the census division level, we analysed changes in correlates of SARS-CoV-2 anti-N seropositivity across three periods in which different variants predominated (pre-Delta, Delta and Omicron). We analysed disparities by geographic area, individual traits (age, sex, race) and neighbourhood factors (urbanicity, material deprivation and social deprivation). Data were from 420 319 blood donations across four regions (Ontario, British Columbia [BC], the Prairies and the Atlantic region) from December 2020 to November 2022.

Results
Seropositivity was higher for racialized minorities, males and individuals in more materially deprived neighbourhoods in the pre-Delta and Delta waves. These subgroup differences dissipated in the Omicron wave as large swaths of the population became infected. Across all waves, seropositivity was higher in younger individuals and those with lower neighbourhood social deprivation. Rural residents had high seropositivity in the Prairies, but not other regions. Compared to generalized linear models, multi-level models with spatial effects had better fit and lower error when predicting SARS-CoV-2 anti-N seropositivity by geographic region.

Conclusions
Correlates of recent COVID-19 infection have evolved over the pandemic. Many disparities lessened during the Omicron wave, but public health intervention may be warranted to address persistently higher burden among young people and those with less social deprivation.
Internal Conflicts and the Moderating Role of Property Rights in Sub-Saharan Africa: Implications for Property Taxation
Authors: Affroumou Tiemele Aristide , Amedanou Isaac 
Published: June 2024

Abstract
We investigate the implications of internal conflicts for property tax revenues and highlight the moderating role of property rights in Sub-Saharan African countries over the period 1996 to 2019. Estimates based on fixed-effects regressions indicate that internal conflicts reduce property tax revenues, and property rights play a moderating role in the influence of internal conflicts on property tax revenues. Specifically, when property rights are clearly defined, the effect of internal conflicts is quantitatively weaker compared to situations where property rights are ambiguous or poorly enforced. Moreover, in addition to the positive impact of protecting property rights on property tax revenues, the estimates also provide evidence of government effectiveness, further reinforcing the interconnected relationship among internal stability, property rights protection and property tax revenues. Finally, among other factors tested, some, such as the level of development, the share of natural resources and the urban population, are also relevant in determining property tax revenues.
Vietnam’s liquefied natural gas demand—potential to import liquefied natural gas from the USA
Authors: Le Minh Thong , Tran Van Hiep , Nguyen Thanh Thuy 
Published: June 2024

Abstract
Vietnam, a dynamic and rapidly developing country in Southeast Asia, is experiencing a surge in energy demand due to its booming economy and growing population. However, with the strong commitment of the Vietnamese government to achieve net-zero emissions by 2050 at COP 26, Vietnam needs to implement robust measures to reduce greenhouse gas emissions, with energy transition as a top priority. To meet this growing energy demand and minimize greenhouse gas emissions in the energy sector, Vietnam is turning its attention to liquefied natural gas (LNG), an environmentally friendly and versatile energy source. With the USA emerging as a major global exporter of LNG based on the shale gas revolution, Vietnam has recognized the potential to import LNG from the USA to meet its energy needs in a sustainable manner. The purpose of this article is to analyse the reasons why Vietnam has prospects for importing LNG from the USA.
Estimation of the Electric Field in Atom Probe Tomography Experiments Using Charge State Ratios
Authors: Tegg Levi , Stephenson Leigh T , Cairney Julie M 
Published: June 2024

Abstract
Kingham [(1982). The post-ionization of field evaporated ions: A theoretical explanation of multiple charge states. Surf Sci116(2), 273–301] provided equations for the probability of observing higher charge states in atom probe tomography (APT) experiments. These “Kingham curves” have wide application in APT, but cannot be analytically transformed to provide the electric field in terms of the easily measured charge state ratio (CSR). Here we provide a numerical scheme for the calculation of Kingham curves and the variation in electric field with CSR. We find the variation in electric field with CSR is well described by a simple two- or three-parameter equation, and the model is accurate to most elements and charge states. The model is applied to experimental APT data of pure aluminium and a microalloyed steel, demonstrating that the methods described in this work can be easily applied to a variety of APT problems to understand electric field variations.
Continuum and line emission from accretion shocks at T tauri stars – I. Correlations with shock parameters
Authors: Kwan John 
Published: June 2024

ABSTRACT
Fourteen models are calculated with the shock velocity ranging from 200 to 330 km s$^{-1}$ and pre-shock hydrogen nucleon density ranging from $2.5\times 10^{12}$ to $4\times 10^{13}$ cm$^{-3}$. Among them the summed emergent flux of all spectral lines accounts for about 0.1–0.3 of the total veiling flux. The hydrogen Balmer continuum accounts for 0.17–0.1, while a nearly constant fraction close to 0.5 comes from emission produced by the stellar atmosphere. The main results derived from the veiling continuum energy distributions are two strong correlations: (1) the Balmer jump (BJ) increases as FK, the shock kinetic energy flux, decreases; and (2) at a fixed fraction of surface coverage by accretion shocks $r_{\lambda }$, the ratio of veiling to photospheric continuum flux at wavelength λ decreases as FK decreases. Using the BJ–FK and $r_{4500\,\mathring{\rm A}}$–FK relations, the observed excess continua of 10 T Tauri stars are modelled. For BP Tau and 3 Orion stars our accretion luminosities are higher than published values by a factor of a few. For the six Chamaeleon I stars, our observed accretion luminosities are about 27–78 per cent higher than corresponding published values. Comparison of model results on the He i λ5876 Å flux with observed data indicates that, while those stars with dominant λ5876 Å narrow components can be readily accounted for by the calculated models, those with much stronger broad components cannot, and suggests that for the latter objects the bulk of their excess continua at 5876 Å do not originate from accretion shocks.
The 5′-terminal stem–loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH
Authors: Toews Sabrina , Wacker Anna , Faison Edgar M , Duchardt-Ferner Elke , Richter Christian , Mathieu Daniel , Bottaro Sandro , Zhang Qi , Schwalbe Harald 
Published: June 2024

Abstract
We present the nuclear magnetic resonance spectroscopy (NMR) solution structure of the 5′-terminal stem loop 5_SL1 (SL1) of the SARS-CoV-2 genome. SL1 contains two A-form helical elements and two regions with non-canonical structure, namely an apical pyrimidine-rich loop and an asymmetric internal loop with one and two nucleotides at the 5′- and 3′-terminal part of the sequence, respectively. The conformational ensemble representing the averaged solution structure of SL1 was validated using NMR residual dipolar coupling (RDC) and small-angle X-ray scattering (SAXS) data. We show that the internal loop is the major binding site for fragments of low molecular weight. This internal loop of SL1 can be stabilized by an A12–C28 interaction that promotes the transient formation of an A+•C base pair. As a consequence, the pKa of the internal loop adenosine A12 is shifted to 5.8, compared to a pKa of 3.63 of free adenosine. Furthermore, applying a recently developed pH-differential mutational profiling (PD-MaP) approach, we not only recapitulated our NMR findings of SL1 but also unveiled multiple sites potentially sensitive to pH across the 5′-UTR of SARS-CoV-2.