bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human Capital Efficiency and Firm Performance of Quality-Certified Firms from EFQM Excellence Model: A Dynamic Panel Data Study
Authors: Yousaf Muhammad 
Published: May 2024

Abstract

Purpose
The study’s main purpose is to investigate the impacts of human capital efficiency (HCE) on the firm performance of non-certified and quality-certified firms from the European Foundation for Quality Management (EFQM) Excellence Model. The study also examines the relationship between firm performance and quality-certificates from the European Foundation.

Design/methodology/approach
By using a sample of 282 non-certified and 22 quality-certified firms from 2017 to 2021, the current study employed a two-step system generalized method of moments (GMM) estimation to analyse the empirical data. The dummy variable is used to examine the relationship between quality-certificates and firm performance. The dummy interaction term is employed to quantify the impacts of HCE on the firm’s performance for quality-certified firms.

Findings
The results revealed that quality-certificates and firm performance have a positive relationship. Quality-certified firms perform better and earn more profits than non-certified firms. HCE has a positive impact on firm performance for both types of firms. Moreover, the quality-certified firms utilize HCE in an efficient way to earn more profits compared to the non-certified firms.

Originality
This is the first study to use a comprehensive analysis to emphasize the HCE for non-certified and quality-certified firms separately. The effects of quality-certificates on firm performance in the context of HCE are also being highlighted for the first time in this research.

Practical implications
The current study’s findings are fruitful for academics, managers, researchers, policymakers, and other firm management. The findings will encourage the management of the firms to implement the total quality management (TQM) approach within their firms.
Intestinal perforation secondary to the use of sodium polystyrene sulfonate, case report
Authors: Adriano-Castro Roberto , Sancho-Muriel Jorge , Cholewa Hanna , Flor-Lorente Blas , Segura Francisco Giner 
Published: May 2024

Background:
The use of cation exchange resins such as sodium polystyrene sulfonate (SPS) in the treatment of hyperkalemia has been associated with potential damage to the gastrointestinal tract.

Case Presentation:
We present a clinical case of a 63-year-old male patient admitted following a single-lung transplant who presented a complex postoperative period associated with renal failure and hyperkalemia, therefore administering SPS. 17 days afterward, the patient presented a clinical exacerbation with acute abdominal pain, due to a sigmoid perforation. The patient underwent urgent surgery, performing an open sigmoidectomy and terminal colostomy. The anatomo-pathological study of the surgical specimen revealed abundant SPS crystals in the depth of the colonic wall.

Conclusion:
Close patient surveillance and high clinical suspicion are essential to prevent potentially fatal complications from the use of SPS. Due to the low incidence of this complication, the evidence in the literature is limited to case reports and retrospective studies.
FORMULATION AND PHARMACOKINETIC EVALUATION OF RITONAVIR FLOATING TABLETS IN THE MANAGEMENT OF AIDS
Authors: Kiran R. Shireesh , Shekar B. Chandra , Babu B. Nagendra 
Published: May 2024

In the current study, gastro-retentive tablets of Ritonavir was developed to increase its oral bioavailability using hydrophilic polymers HPMC K 4M, K 15M, and K 100M as release retarding agents. Polyox WSR 303 was chosen as resin, sodium bicarbonate was used as effervescent agents. The tablets were prepared by direct compression method and FTIR studies revealed that there is no interaction between the drug and polymers used for the formulation. Among all the formulations F21 containing HPMC K 100M, Crospovidone, Polyox WSR 303 and sodium bicarbonate, as gas generating agent was choosen as optimized formulation based on the evaluation parameters, floating lag time (33 sec) and total floating time (>24 h) and in vitro dissolution studies. From in vitro dissolution studies, the optimized formulation F21 and marketed product was shown 98.67% and 95.09 ± 5.01% of drug release respectively. From in vivo bioavailability studies, after oral administration of floating tablet containing 100 mg Ritonavir, the Cmax, Tmax, and AUC0–∞ of optimized gastroretentive formulation were found to be 30.11 ± 1.16µg/mL, 8.00±1.23 h and 173 ± 26.34µg*h/ml, respectively. Cmax and AUC values of optimized formulation were found to be significantly higher than of marketed product, where longer gastric residence time is an important condition for prolonged or controlled drug release and also for improved bioavailability.
Ethanolic Extract of <i>Alternanthera Sessilis</i>: A Potential Therapeutic Agent for Behavioral Improvements in Reserpine-Induced Parkinsonian Rats
Authors: S Syed Liyakath Ali , P. V. Balaji , R Aravind Kumar , M Thirumaran , V Manibalan 
Published: May 2024

The present study evaluated the potential of an ethanol extract from Alternanthera sessilis to alleviate reserpine-induced Parkinson's disease (PD) like behavioural manifestations in rats. The animals were grouped into five: a control group, a group receiving only reserpine, a group treated with levodopa and carbidopa, and two groups given different doses of the Alternanthera sessilis extract. Reserpine was used to mimic PD symptoms, while the extract was administered orally at two different concentrations. The behavioral tests were conducted to assess locomotor activity, grip strength, catalepsy, and rearing activity. Locomotor activity was measured using an actophotometer, where interruptions in light beams caused by the rates were recorded over a 10-minute period. Grip strength was evaluated using a rotarod apparatus, measuring the time taken for rats to fall off individual rods. Catalepsy was assessed through a bar test, measuring the time for rats to descend from a horizontal bar to the base. Rearing activity was observed in a round open field arena, with parameters including the occurrence rate of rearing, general movements score, and duration spent in the center of the arena. The results revealed administration of reserpine led to a decrease in body weight, locomotor activity, muscle coordination, catalepsy score, rearing activity, and grip strength compared to the control group. Conversely, treatment with levodopa and carbidopa resulted in increased values for these parameters. Importantly, administration of Alternanthera sessilis extract showed a dose-dependent reversal of the effects induced by reserpine, with significant increases observed in body weight, locomotor activity, muscle coordination, rearing activity, general movement, and grip strength, indicating its potential therapeutic effects. In conclusion, the present study results suggest that the extract from the Alternanthera sessilis plant might protect brain cells and improve symptoms of Parkinson's disease. However, more research is needed to understand how it works and if it can be used safely and effectively clinical trails.
Androgenetic Alopecia: update on Etiology, Pathophysiology, Diagnosis and Treatment
Authors: P Cherishma Raju , Baraka Babiker Bashir Haroun , Rao Bhagya V , Karadi Chetana S , Gowda Sneha V , Kumar Ramesh 
Published: May 2024

Alopecia means loss of hair. Androgenetic alopecia (AGA) now called as patterned hair loss (male pattern hair loss; MPHL, female pattern hair loss; FPHL) is caused by androgens in a predisposed individual. It is modulated by factors like age, sex, genes, smoking, and alcohol. If untreated this leads to psychological problems like stress, anxiety, depression and decrease self-confidence which affect quality of life. A thorough clinical examination and a certain hormonal estimation could reveal levels of androgens, hyperandrogenism, adrenal hyperplasia, (PCOS) polycystic ovarian syndrome, and ovarian/adrenal tumors. A simple Trichoscopy could show the typical picture of hair miniaturization commonly seen in this condition. Finally, a biopsy of the scalp could help in clinching conclusive diagnosis. Out of the many treatments at our disposal, the non-pharmacologic methods like temporary camouflage techniques, synthetic hair wigs, hair-thickening fibers, hair weaving, pigmented powders are useful. Semi-permanent options like scalp micro-pigmentation (thorough tattooing) are useful to enhance appearances. Presently the United States Food and Drug Administration (USFDA) approved pharmacologic treatments are Minoxidil and Finasteride. The non-USFDA approved methods of treatments like various surgical procedures {[hair transplantation]: follicular unit transplantation (FUT), follicular unit extraction (FUE), microneedling, light therapy, indigenous medicines, Platelet-Rich Plasma (PRP)}, and various loco-regional hair care practices are in vogue. The outcome of this review is to offer the latest update and insights into the newer novel therapies in patterned hair loss. Also, the patients could enhance their knowledge about the condition, the benefits and prognosis of each treatment.
Bourdieu e Passeron vão ao campo: abordagem teórico-metodológica
Authors: Andreatta Whitaker Dulce Consuelo , Flores Ana Flávia , Mariano Thatiany , Botta Ferrante Vera Lucia Silveira , Ferri Cintrão Janaina Florinda 
Published: May 2024

A intenção deste artigo é demonstrar possibilidades da abordagem baseada na análise dialética quando tentamos explicar o real a partir de teorias formuladas em outros contextos – no caso aqui, a Teoria da Reprodução. Para tanto, estamos confrontando a elaboradíssima Teoria de Bourdieu e Passeron (1975) com os dados de uma entrevista bastante expressiva que nos foi concedida por uma jovem criada na zona rural – um assentamento de Reforma Agrária – jovem esta que alcançou altos níveis de escolaridade atingindo curso superior de prestígio em universidade pública, superando, portanto, a objetividade do real, ou seja, os obstáculos previstos enfaticamente pela “Grande Teoria”, os quais inegavelmente atuam no nível sistêmico.
Reflections of Postcolonial Trauma in Lisa Ko’s The Leavers
Authors: Al-Douri Hamdi Hameed , Abdul-Aziz Shaymaa Saber 
Published: May 2024

The term "trauma" is used to describe ambiguous and long-term harms. The study of psychological trauma has led to the creative representation of literary trauma. Even though the cultural trauma theory is increasingly criticized as being unsuitable for the research agenda of postcolonial studies, the diversity and expanding number of responses to it in postcolonial criticism show the theory's continued appeal. The key question in the discussion of trauma theory and postcolonial literary studies is still whether trauma theory can be successfully "postcolonized" in the sense of being usefully combined with postcolonial theory. Maybe this is one of the unique abilities of literary criticism: to develop the capacity to recognize connections that we were previously unaware of. The search shows the significance of finding closure to transcend past ordeals. The search is an analytical study of Lisa Ko’s novel Leavers. It gives a brief background to the novel and the novelist which displays in what way the novel tackles postcolonial trauma. The main two characters who suffer trauma show the possibility of trauma recovery by achieving their closures. The novel succeeds in depicting trauma and achieving recovery through the main character’s pursuit to find his closure. The study also demonstrates that despite the multiplicity of traumatic causatives, victims have significant symptoms, and their lives and destiny are contingent on their abilities to achieve closure.
Modern Utopia: Yuval Noah Harari
Authors: Kornienko Natalia Vladimirovna 
Published: May 2024

The article is devoted to the analysis of the current state of utopia, in particular, attention is paid to the problem of the crisis of utopian thought that arose at the end of the twentieth century and continues to the present. The author examines the features of philosophical criticism of modernity by the ideologist of the future and futurist Yuval Noah Harari. The purpose of this study is to find out whether Yuval Noah Harari is a utopian of our time, and the model of the near future proposed by Y. Harari, which represents a natural reaction of society to the global value and ideological crisis, is a modern utopia by signs. In the course of researching issues related to the crisis of utopian thought of our time, the author proceeds from the postulate that utopia is a special type of predictive reflection, a worldview built in orientation towards the probable future. The research is based on the concept of K. Manheim, according to which utopia is an attitude of consciousness oriented towards the future, as well as from the definition of utopia as an idealized social construct, fundamentally unrealizable as a whole. The scientific novelty of this study is as follows: the main concepts of understanding modern utopia are identified, the specifics of describing the realities of modernity are substantiated, characteristics relevant to the worldview of the XXI century are identified, proceeding from the categories of philosophizing of a new kind, the features of Yuval Noah Harari's criticism of the utopia of a new formation are revealed. The result of the study shows that Yuval Noah Harari is a modern utopian, and his project is considered an escapist-type utopia of modernity, based on social stratification. This utopia is escapist, because for one part of humanity it is unrealizable and is only a means of escape from reality, while for another part of it it can serve as a full-fledged project of the future, claiming to be realized. It also has such an ontological property as temporality, since it corresponds to the realities of its time in terms of content.
Exposure to Mycophenolic Acid and Its Clinical Response in an Indian Pediatric Population with Nephrotic Syndrome
Authors: Deepthi R. V. , Arumadi Manjusha , Eriyat Vishnu , Mathew Sumith K. , Mathew Binu S. , Agarwal Indira , Prabha Ratna 
Published: May 2024

Background:Children with nephrotic syndrome experience many side effects and frequent relapses when treated with steroids and other drugs. Mycophenolic acid (MPA) is one of the effective and least toxic drug for the treatment of nephrotic syndrome. This drug needs to be monitored for maximal efficacy and minimal toxicity. The therapeutic reference range for this drug is not established for the aforementioned patient population of Indian origin.
Materials and Methods:In this observational study, children with nephrotic syndrome on mycophenolate mofetil were followed up for a minimum duration of three months. Following this, their clinical status (relapse/remission) was determined and the mycophenolate exposure was measured for over 12 hours.
Results:A total of 34 participants were included, with 17 (50%) in relapse. Median MPA Area under the curve over 12 hours (AUC0–12h) (36.5 µg·h/ml) in the remission group differed significantly compared to that in the relapse group (17.2 µg·h/ml).
Conclusion:Higher exposure to MPA AUC0–12h is associated with clinical remission of pediatric nephrotic syndrome.
Using eGFR and Albumin Creatinine Ratio as an Initial Screening Tool in Trinidadian Primary Care to Identify High-risk Population for CKD: A Cross-Sectional Study
Authors: Mahadevappa Karthik , Nayak Shivananda B. , Maharaj Rohan G. , Bhaktha Geetha 
Published: May 2024

Background:Chronic kidney disease (CKD) is a major public health burden and is often undiagnosed in the primary care setting. Untested and untreated, this often leads to renal failure and dialysis.
Materials and Methods:This was a cross-sectional study of adults aged 20 years and over, diagnosed with type 2 diabetes mellitus and/or hypertension, with no previous history or record of CKD, and attending three chronic disease clinics in the Eastern Regional Health Authority (ERHA). Patients were screened for risk of CKD by using the albumin creatinine ratio. The eGFR was calculated based on serum creatinine by using the CKD Epidemiology Collaboration (EPI) 2009 equation.
Results:In total, 430 patients agreed to participate with 61.2% of response rate. Of the 385 with complete data, 357 (92%) were detected as having a high risk for CKD; older patients (>66 years) and those with both diabetes and hypertension had high proportions of risk for CKD. There were significant associations between age, systolic hypertension, and the severity of risk for CKD.
Conclusion:CKD is common at the primary care level among adults with NCDs in Trinidad, with many patients having been left out without being tested for CKD. Primary care physicians must take this into consideration in caring for NCD patients.
PSYCHOLOGICAL STUDIES OF CREATIVITY IN WRITING
Authors: Basri Nurfajriah , Nur Sahril , Salija Kisman , Nur Safar 
Published: May 2024

This paper is a critical literature review of psychological studies of creativity in writing from the top studies year 2013 until 2022 and compares crucial criteria and techniques. This systematic review attempts to address three research questions, i.e What is the research theory of existing studies that are being investigated based on a systematic literature review, what psychological aspects of creative writing are discussed in the reviewed paper, and what research methods were used in the studies that were included. Eight studies systematically reviewed all aspects of psychology from these studies, the findings of this study also mostly measured students’ motivation in creating writing from various education levels. Mostly, the previous researcher used a quantitative method to analyze the data that were 4 articles in the reviewed paper. Meanwhile, a similar number of articles were qualitative and quantitative methods. Keywords: Psychological studies, Creativity in writing, systematic review
CHARACTER EDUCATIONAL VALUES IN ENCANTO ANIMATION MOVIE
Authors: Sari Rensi Kumala , Baluqiah Kiagus , Susyla Dian , Angraini Ria 
Published: May 2024

This research aimed to find out and describe the types of character educational values conveyed in Encanto animation movie. This research used descriptive qualitative method. The researchers used Kemendikbud formulation to analyze character educational values. The 18 types of character educational values, based on Kemendikbud includes religious, honesty, tolerance, discipline, hardworking, creativity, independent, democratic, curiosity, national spirit, love for the homeland, appreciate achievement, communicative, love peace, likes to read, cares about the environment, cares about social, and responsibility. In this research only 11-character educational values were found. They are honesty, tolerance, discipline, creativity, curiosity, love for the homeland, appreciate achievement, communicative, love peace, cares about social, responsibility. So, there are 7-character educational values that have not been conveyed in Encanto animation movie. They are religious, independent, democratic, hardworking, national spirit, likes to read, and cares about the environment. There are 58 dialogues conveyed as the character educational values. Those are 2 values of honesty, 1 value of tolerance, 1 value of discipline, 3 values of creativity, 13 values of curiosity, 1 value of love for the homeland, 2 values of appreciate achievement, 4 values of communicative, 8 values of love peace, 22 values of cares about social, and 1 value of responsibility. Then, the researchers found the dominant character educational values in the movie is cares about social which is conveyed in 22 dialogues.
VOCATIONAL HIGH SCHOOL ENGLISH TEACHERS’ VOICE OF CURRICULUM CHANGE
Authors: Sukawati Dewi , Suwartono Tono , Palupi Asti Diah 
Published: May 2024

Teachers' attitudes toward curricular changes cause a variety of challenges regarding the implementation of school-based teaching and learning. The objective of this descriptive-qualitative research is to explore teachers' voice toward curriculum change from 2013 Curriculum to Freedom-to-Learn Curriculum at private vocational high schools. Data was gathered from two vocational high school English teachers volunteers in Banyumas City, Indonesia. They were recruited through convenience sampling. In-depth interviews and corresponding documents were used to obtain data. The interview focuses on teachers' understanding of the curricula, administration, assessment system implemented, and teachers' attitudes toward curriculum change. The results reveal that, at the time the study was carried out, the teachers understood both the 2013 Curriculum and Freedom-to-Learn Curriculum. They were able to adjust to changes in the administration procedure and the evaluation system. They agreed that it is too soon to see the effects of the newly implemented Freedom-to-Learn Curriculum by now, while believing the curriculum will find its way with a better understanding and execution over time. The researcher urges other researchers to do further investigations on this qualitative approach related to a broader issue, more general data, and more relevant methods.
Promoting Straw Recycling to Accelerate the Sustainable Development of Agriculture
Authors: Liu Xinyi , Li Tingting , Fang Yujia , Lu Xiaochuan 
Published: May 2024

Guided by Xi Jinping’s thought of socialism of the new era with Chinese characteristics in the 14th Five-Year Plan, the comprehensive utilization of straw is closely integrated with the annual key tasks of improving rural areas, by adhering to the priority of agricultural use, industry-oriented, multi-measures, and focusing on counties and municipalities with larger amounts of straw resources. Agricultural modernization requires that provincial policies focus on promoting the utilization of straw as fertilizer, feed, energy production, substrate, raw material, and so on while emphasizing the establishment of a complete straw collection, storage, and transportation system. In response to the problem of the open burning of straw in recent years, China has adopted a variety of policies and measures to control pollution and rationally utilize straw resources. The state and provinces have issued many policy documents on straw resource management, which are divided into the management of straw burning, comprehensive utilization of straw, planning of the straw energy industry, and financial subsidies. Rational utilization of straw not only solves the key issues of employment of farmers but also promotes ecological efficiency and rural economic development. The research results of straw recycling have also made important progress in improving the utilization rate and value of straw, promoting the resource utilization of agricultural waste, and providing important technical support for the sustainable development of China’s agriculture and rural environmental protection.
Exploring the Path of Cultivating “Three Spirits” in Higher Vocational Colleges and Universities
Authors: Guo Chunyang 
Published: May 2024

The “three spirits” is a strategic concept for the comprehensive construction of a strong modernized socialist country in the new era, and it is an important way for higher vocational colleges to cultivate high-quality technical and skilled talents. The “three spirits” consist of the spirit of labor, the spirit of model workers, and the spirit of craftsmanship. This paper proposes labor education as the basis, three-dimensional coeducation of classroom, extracurricular, and practical, and integration of school and enterprise in cultivation, to explore practical ways to cultivate the “three spirits” in higher vocational students.