bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prioritizing Maintenance Strategies for Efficient Forklift Performance Through Failure Analysis
Authors: Rizky Naufal , Sulistiyowati Wiwik 
Published: June 2024

This study addresses forklift maintenance challenges at PT. Karya Mitra Teknik, focusing on undisciplined operators and overuse issues. Using Failure Mode And Effect Analysis (FMEA) and Fault Tree Analysis (FTA), it identifies root causes and suggests improvements. Data collected through observations, interviews, and flow diagrams pinpoint three priority failure modes: radiator, starter dynamo, and oil flow failure. Recommendations emphasize regular maintenance, cleanliness, and enhanced operational practices for effective issue mitigation.

Highlight:

Root Cause Analysis with FMEA and FTA.
Prioritizing Critical Failure Modes.
Recommend Disciplined Maintenance for Operational Enhancements.

Keyword: Forklift Maintenance, Root Cause Analysis, Improvement Recommendations, FMEA, FTA
Intellectual systems of pattern and meaning recognition in the system of prevention of crimes committed using the Internet
Authors: Zharova A. K. 
Published: June 2024

Objective: to study the issues of legal regulation of intellectual systems for pattern and meaning recognition as part of the system to prevent and suppress offenses committed using information and telecommunication network.Methods: dialectical approach to the cognition of social phenomena, which allows analyzing them in their historical development and functioning in the context of objective and subjective factors, which determined the choice of the following research methods: formal-legal, comparative-legal, legal modeling, set theory, graph theory.Results: prevention of offenses includes prophylaxis and procedural forms of prevention of offenses. These two sets of forms share measures to eliminate the circumstances that contribute to the commission of offenses. However, the set of procedural forms of prevention does not include identification of causes and conditions contributing to the commission of offenses. Procedural forms aim at preventing specific types of offenses, while prevention to some extent uses the methods of predictive analytics, assuming the possibility of a negative antisocial event and using various organizational, technological and legal tools and measures. Consequently, prediction of criminal actions is one of the stages of prevention of offenses carried out using predictive analytics of data left by a person. The accuracy of calculations carried out by artificial intelligence (AI) is increasing every year; hence, the accuracy of the obtained probabilities and forecasts is also increasing.Scientific novelty: the article presents an interdisciplinary study of preventing negative social deviations occurring with the use of information and telecommunication network by means of interaction between the hosting providers, using intelligent systems of pattern and meaning recognition, and law enforcement agencies. It was established that the application of AI by law enforcement agencies and their interaction with hosting providers allows not only to identify illegal and socially dangerous content, but also to assess the probability of committing a crime by a particular person. Application of AI by hosting providers allows preventing illegal actions. This can be done by revealing the stage of criminal intent expressed in the information posted by a potential offender, thus minimizing the possibility of the intent outgrowth into real criminal actions.Practical significance: the main provisions and conclusions of the article can be used in scientific, pedagogical and law enforcement activities when considering issues related to the legal regulation of AI algorithms, the possibility of their application in order to prevent and suppress offenses committed with the use of information and telecommunications network.
Incentives and constraints in the system of ensuring anti-corruption security (overview of the 7th Siberian Anti-Corruption Forum)
Authors: Damm I. A. , Tarbagaev A. N. , Koptseva N. P. , Akunchenko E. A. , Dyachenko A. E. 
Published: June 2024

Objective: to review the results of the 7th Siberian Anti-Corruption Forum “Incentives and Restrictions in the System of Anticorruption Security” held in Krasnoyarsk on December 15-16, 2023 (organizers: Siberian Federal University, Krasnoyarsk Krai Governor’s Administration, Krasnoyarsk Krai Prosecutor’s Office, Krasnoyarsk Krai Department of the Ministry of Justice of Russia for Krasnoyarsk Krai, Krasnoyarsk Regional Branch of the Russian Lawyers’ Association).Methods: general scientific method of dialectical cognition, as well as a number of private scientific methods, such as historicallegal, system-structural, comparative-legal, formal-logical (deduction, induction, definition and division of the concept), etc.Results: the forum discussed the following key topics: anti-corruption security as an integrative scientific category, the role of incentives and restrictions in the system of its provision; history of development, concept, types and system of anti-corruption incentives and restrictions; international legal regulation of incentives and restrictions in the system of anticorruption security; foreign and Russian experience of resource provision of anti-corruption incentives and restrictions; the role of law enforcement agencies and civil society institutions in providing anti-corruption security; anti-corruption potential of digitalization processes, etc.Scientific novelty: the leading idea of the Forum scientific and practical dialogue was harmonization of anti-corruption incentives and restrictions, since the search for a successful combination of these tools will create legal prerequisites for a qualitative transition to a new model of anti-corruption activities and ensure the security of individuals, society and the state from various corruption threats.Practical significance: based on the Forum results, the author formulated proposals aimed at improving the state policy in the field of combating corruption, as well as the anti-corruption activities of various subjects. These results are of interest to scientists, educators, law enforcement officials, and all those interested in the issues of combating corruption.
WITHDRAWN: Mitochondrial accumulation induced axon dysfunction promotes paranode instability and demyelination in hypoxic-ischemic forms of demyelination
Authors: Cui Mei , Feng Yiwei , Guo Min , Zhao Hongchen , Han Sida , Zhao Yanxing , Dong Qiang 
Published: June 2024

Abstract

The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Enhanced Eeg Signal Classification for Motor Imagery Based Brain Computer Interface: A Fusion Approach Using Discrete Wavelet Transform and Quad Binary Pattern
Authors: Ananthi A. , Subathra M.S.P. , S Thomas George , N.J Sairamya 
Published: June 2024

Abstract

Motor Imagery - Brain-Computer Interface (MI-BCI) is a technique that acts as a non-muscular channel for disabled people to communicate. Because it is a communication link between the wired brain and an external device. In this paper, we propose a comprehensive feature extraction approach for electroencephalogram (EEG) signals to achieve maximum classification accuracy by fusion techniques. The Wavelet Packet Decomposition (WPD), Discrete Wavelet Transform (DWT), and Quad Binary Pattern (QBP) methods are applied to EEG signals. The proposed method consists of five strategies out of which two are fusion techniques based on EEG signal and pattern techniques. One hybrid method involves decomposing EEG signals using DWT, and feeding it into the QBP domain to extract the histogram features. In another hybrid model, the signals are decomposed using WPD and were given to the QBP for feature extraction. Artificial Neural Network (ANN) is used as a classifier in our work. Among the used algorithm DWT based QBP approach attained maximum accuracy. The proposed method is validated using well-known Physionet EEG dataset by considering binary class (imaginary movement of left and right fist). The extracted features are to classify the movement of the right and left fist EEG signals. Using a DWT-based QBP approach, the proposed technique attained a accuracy of 99.50 percent on physionet dataset.
Investigating the role and contribution of soluble carbohydrates remobilization after pollination in grain yield of some wheat cultivars
Authors: Arefkhani Mona , Karizaki ALI Rahemi , Biabani Abbas , Sabori Hossein , Rassam Ghorbanali 
Published: June 2024

Abstract

Understanding the wheat grain yield in terms of assimilation, remobilization and translocation the photosynthetic assimilates and the contribution of plant organs in grain filling is one of the future breeding necessary strategies. The aim of the present research to evaluate the indicators of photosynthetic assimilate remobilization of wheat cultivars that were released during the years 1991 to 2016. For this purpose, the experiment was conducted in the form of randomized complete block design in 3 replications during two crop years 2018–2019 and 2019–2020 in Shirvan Higher Education Complex Research Farm in North Khorasan, Iran. The results indicated the variability of photosynthetic assimilate remobilization potential from different organs among cultivars, and the relationship between the cultivars genetic diversity and the photosynthetic assimilate remobilization of different organs. Indeed, the greatest remobilization, contribution and efficiency of photosynthetic assimilate remobilization were observed in Ehsan, Karim and Gonbad cultivars. Also, the remobilization rate, contribution and efficiency of photosynthetic assimilate remobilization from flag leaf, peduncle and penultimate has increased during the last few decades in Iran during breeding activity. The results showed that the photosynthetic assimilate remobilization increased from the flag leaf and peduncle is about 8.7%, and 5% from penultimate per one year of release. The contribution of remobilization from different organs to grain yield was in the order of peduncle > penultimate > flag leaf. However, there were no significant differences in the photosynthetic assimilate remobilization efficiency between different organs and it was on average about 5% per one year of release.
Platinum-based Catalysts for Oxygen Reduction Reaction simulated with aQuantum Computer
Authors: Paola Cono Di , Plekhanov Evgeny , Krompiec Michal , Kumar Chandan , Marsili Emanuele , Du Fengmin , Weber Daniel , Krauser Jasper , Shishenina Elvira , Ramo David Muñoz 
Published: June 2024

Abstract

Hydrogen has emerged as a promising energy source, holding the key to achieve low-carbon and sustainable mobility. However, its applications are still limited by modest conversion efficiency in the electrocatalytic oxygen reduction reaction (ORR) within fuel cells. Consequently, the development of novel catalysts and a profound understanding of the underlying reactions have become of paramount importance. The complex nature of the ORR potential energy landscape and the presence of strong electronic correlations present challenges to atomistic modelling using classical computers. This scenario opens new avenues for the implementation of novel quantum computing workflows to address these molecular systems. Here, we present a pioneering study that combines classical and quantum computational approaches to investigate the ORR on pure platinum and platinum/cobalt surfaces. Our research demonstrates, for the first time, the feasibility of implementing this workflow on the H1-series trapped-ion quantum computer and identify the challenges of the quantum chemistry modelling of this reaction. The results highlight the involvement of strongly correlated species in the cobalt-containing catalyst, suggesting their potential as ideal candidates for showcasing quantum advantage in future applications.
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis
Authors: LOISON Ingrid , PIOGER Adrien , PAGET Sonia , METATLA Ines , Consortium OrgaRES , Vincent Audrey , ABBADIE Corinne , DEHENNAUT Vanessa 
Published: June 2024

Abstract

The potential use of pro-senescence therapies, known as TIS (Therapy-Induced Senescence), for the treatment of colorectal cancer (CRC) generated significant interest since they require lower doses compared to those required for inducing apoptosis. However, the senescent cell cycle-arrested cancer cells are long-lived, and studies have revealed escape mechanisms contributing to tumor recurrence. To deepen our understanding of the survival pathways used by senescent cancer cells, we delved into the potential involvement of the hexosamine biosynthetic pathway (HBP). HBP provides UDP-GlcNAc, the substrate for O-GlcNAc transferase (OGT), which catalyzes O-GlcNAcylation, a post-translational modification implicated in regulating numerous cellular functions and aberrantly elevated in CRC. In this study, we demonstrated that TIS induced in HCT116 and LS174T colorectal cancer cells by low-dose SN38 or etoposide treatment was accompanied with a decrease of GFAT (the rate limiting enzyme of the HBP), OGT and O-GlcNAcase (OGA) expression correlated with a slight reduction in O-GlcNAcylation levels. Further decreasing this level of O-GlcNAcylation by knocking-down GFAT or OGT redirected the response to subtoxic chemotherapy doses from senescence to apoptosis, in correlation with an enhancement of DNA damages. Pharmacological inhibition of OGT with OSMI-4 in HCT116 and LS174T cells and in a patient-derived colon tumoroid model supported these findings. Taken together, these results suggest that combing O-GlcNAcylation inhibitors to low doses of conventional chemotherapeutic drugs could potentially reduce treatment side effects while preserving efficacy. Furthermore, this approach may increase treatment specificity, as CRC cells exhibit higher O-GlcNAcylation levels compared to normal tissues.
Reducing classical communication costs in multiplexed quantum repeaters using hardware-aware quasi-local policies
Authors: Haldar Stav , Barge Pratik , Cheng Xiang , Chang Kai-Chi , Kirby Brian , Khatri Sumeet , Wong Chee Wei , Lee Hwang 
Published: June 2024

Abstract

Future quantum networks will have nodes equipped with multiple quantum memories, allowing for multiplexing and entanglement distillation. In this work, we introduce "quasi-local" policies for multiplexed quantum repeater chains. In fully-local policies, nodes make decisions based only on knowledge of their own states. In our quasi-local policies, nodes have increased knowledge of state of the repeater chain, but not necessarily global knowledge. Our policies exploit the observation that for most decisions the nodes have to make, they only need to have information about the connected region of the chain they belong to, and not the entire chain. In this way, we not only obtain improved performance over local policies, but we reduce the classical communication (CC) costs inherent to global-knowledge policies. Our policies also outperform the well-known and widely studied nested purification and doubling swapping policy in practically relevant parameter regimes. Via analytical and numerical results, we also identify the parameter regimes in which distillation makes sense and is useful. We also address the question: "Should we distill before swapping, or vice versa?'' Finally, we propose an experimental implementation of a multiplexing-based repeater chain, and experimentally demonstrate the key element, a high-dimensional biphoton frequency comb, and evaluate its anticipated performance.
Evaluation of Aerosol Loading and its Relationship with Geopotential Height in Nigeria’s Guinea Coast
Authors: Ibe Onyinyechi Caroline , Nwofor Okechukwu Kelechi , Okoro Ugochukwu Kingsley 
Published: June 2024

Abstract

The aim of this research work is to assess the spatial and temporal distribution of aerosol optical depth over Nigeria’s Guinea Coast (Longitude 3–12°E, Latitude 4–9°N) comparing aerosol loading within the Guinea Coast region of Nigeria, investigating the relationship between aerosol loading and geopotential height, assessing the vertical distribution of aerosol loading and ascertaining the relationship between aerosol loading and observe the effects of meteorological factors on aerosol loading. Aerosol optical depth data was obtained from the Moderate Resolution Imaging Spectro-radiometer, while the geopotential height and meteorological parameters were retrieved from the Modern-Era Retrospective Analysis for Research and Applications-2 platform. The result obtained showed that aerosol loading/distribution was highest during the dry seasons, especially the coastal areas like Lagos, Warri, and Port Harcourt; this is the season when harmattan dust prevails. Aerosol loading was less in the study location during the dry season because of wet scavenging during this period. Geopotential height values tends to be increasing in the study location. In assessing the vertical distribution of aerosols at different pressure levels, a positive significant association was noticed between aerosol optical depth and geopotential height. It also noted a higher wind speed in the north and the coast of the study region and lower in the south of the region; with the specific humidity pattern at 1000-hpa directly correlating with geopotential height and inversely with wind speed.
Factors associated with pre-treatment hyperferritinemia in patients with chronic hepatitis C virus infection
Authors: Chang Yu Ping , Huang Chiuan-Bo , Kao Jia-Horng , Su Tung-Hung , Huang Shang-Chin , Tseng Tai-Chung , Chen Pei-Jer , Liu Chun-Jen , Liu Chen-Hua 
Published: June 2024

Abstract

Pre-treatment host and viral factors may affect serum ferritin levels in patients with hepatitis C virus (HCV) infection. We delineated pre-treatment factors associated with hyperferritinemia in these patients. 1682 eligible patients underwent pre-treatment assessment for serum ferritin and various host/viral factors. Univariate and multivariate logistic regression analyses were conducted to evaluate factors associated with hyperferritinemia. Multivariate logistic regression analyses revealed that age > 50 years (adjusted odds ratio [OR]: 1.38 (95% confidence interval [CI]: 1.09–1.74), p = 0.008), fibrosis stage ≥ F3 (adjusted OR: 1.36 (95% CI: 1.04–1.77), p = 0.02), fibrosis index based on four parameters (FIB-4) > 3.25 (adjusted OR: 1.46 (95% CI: 1.11–1.92), p = 0.01), presence of metabolic dysfunction-associated steatotic liver disease (MASLD) (adjusted OR: 1.43 (95% CI: 1.21–1.76), p = 0.001), and alanine transaminase (ALT) > 2 folds upper limit of normal (ULN) (adjusted OR: 2.87 (95% CI: 2.20–3.75), p < 0.001) were associated hyperferritinemia. The log10 value of HBV or HCV viral load was not associated with the log10 value of ferritin level (Spearman’s rank correlation coefficient: -0.025, p = 0.81 and 0.002, p = 0.92). In conclusion, host factors, rather than viral factors, are associated with hyperferritinemia in patients with HCV.
Precision Medicine in Obesity: Revealing the Role of SPON2 in Inflammation Through Gwas Analysis in Admixture Brazilian Population.
Authors: Costa Ryan , Coelho Raísa , Cruz Álvaro , Teixeira Helena , Melo Ana Paula , Silva Hatilla , Gomes Luciano , Costa Gustavo , Santana Cinthia , Machado Adelmir , Pinheiro Gabriela , Campbell Monica , Rafaels Nicholas , Barnes Kathleen , Barreto Mauricio L , Figueiredo Camila , Fernandes Jamile 
Published: June 2024

Abstract

Introduction: Obesity is recognized as a chronic condition with a multifactorial etiology, marked by persistent systemic low-level inflammation.
Objectives: This study aims to explore and evaluate the role of genetic factors in predisposition to obesity within a diverse, mixed-race population.
Methods: We conducted a Genome-Wide Association Study (GWAS) involving 1,036 individuals, comprising 333 eutrophic and 703 people with overweight, to pinpoint genetic variants linked to obesity. Genotyping was carried out using the MEGA chip by Illumina. Following this, imputation was performed using the CAAPA reference panel. We conducted in silico analyses using different platforms. Additionally, in a subset of 657 participants, we quantified levels of 11 cytokines (Eotaxin, IFNγ, IL-10, IL-6, IL-12, IL-13, IL-17A, IL-1β, IL-5, IL-8, and TNFα) in peripheral blood. We examined their relationship with the genotypes of the variants identified in the GWAS study.
Results: We identified thirty-five variants that exhibited suggestive associations (5 x 10-8 < p-value < 1 x 10-5) with weight excess. Chromosome 4 harbored the main genes linked to this outcome (SPON2, RNF212, COL4A3, TMED11P and PCSK2) expressed in adipose tissue. Furthermore, we found a variant within the ZZEF1 gene on chromosome 17. Notably, variants such as rs10014526-T and rs77703123-T, in TMED11P displayed high linkage disequilibrium (LD) with variants in SPON2, rs75448245-G, rs11538062-T and rs75654334-T and in COL4A3, rs13419630-A, all negatively associated with the outcome. In contrast, the rs781851-G variant, in the ZZEF1 gene showed a positive association with the outcome. These polymorphic alleles were associated with variations in serum levels of the cytokines IL-6, IL-10, and IL-12.
Conclusions: Our study implies that candidate genes linked to weight excess, notably SPON2, are connected to a perturbed immune pathway that underlies the characteristic inflammation seen in obesity. These novel uncovered associations in our study could potentially advance the field of precision medicine to treat obesity.
Intradermally injected abobotulinumtoxinA, administered in intact animals preemptively, before surgery, alleviates post-surgical pain, reduces distress and normalizes behavior in a translational animal model
Authors: Kalinichev Mikhail , Cornet Sylvie , Castel David , Meilin Sigal , Horne Ron , Pons Laurent , Evans Stephen M. , Lezmi Stephane 
Published: June 2024

Abstract

Previously, abobotulinumtoxinA (aboBoNT-A) injected intraoperatively using intradermal (ID) route was shown to result in effective, but delayed post-surgical analgesia in pigs. Here, we explore the efficacy of preemptively administered aboBoNT-A in intact animals on pain and associated anxiety/depression-like reactivity following a surgery on the lower back of pigs. AboBoNT-A (200 U/animal) or saline, distributed across ten injection points, were injected around anticipated incision via ID route 15, 5, or 1 day before surgery (part A) or via ID, intramuscular (IM) or subcutaneous (SC) routes 15 days before surgery (part B). Animals were assessed for mechanical sensitivity, distress behaviors, and latency to approach the investigator before and after surgery for 7 days. AboBoNT-A, injected ID 15 days before surgery, didn’t alter any baseline behaviors, but largely prevented the onset of post-surgical allodynia, distress and normalized approaching behavior. Injections made 5 days before surgery led to similar analgesic responses, while those made 1 day before surgery were less effective. IM or SC injections of aboBoNT-A were ineffective. Thus, aboBoNT-A administered ID between 15 and 5 days before surgery represents the most optimal conditions for postoperative analgesia. These findings warrant for clinical investigation of analgesic efficacy of preemptively administered aboBoNT-A in postsurgical pain.