bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unbalanced between Work Ethic and Result of Poor Families in Alue Naga Community
Authors: Sa'i  
Published: April 2024

Abstract

Work Ethic is one of the important keys to get maximum results. In Aceh there is a pearl of wisdom about work ethic: Menyoe hana tausaha pane atra roet di manyang (if we do not work, there won’t be treasures falling from the sky). Poverty is not without causes; among the causes is work ethic. This paper looks at the work ethic of families in Gampong Alue Naga, especially the youth, because they are the most potential members of society. The study used qualitative design with descriptive analysis. Data was obtained through observation, interviews and documentation. The results showed that the family work ethic in Alue Naga was considered very good, however, they still lived poor lives. Based on the study, there were some factors affecting their work results, such as: narrow employment opportunities; their work as fishermen was still using traditional method, their equipment for work such as boats, trawls; fishing rods were still very limited in numbers and their work was also not supported by sufficient skills. Therefore, despite the high work ethic, the majority of people in this Gampong (village) were still poor. It proved that work ethic alone is not enough to gain a better income. It is highly suggested that the government and related parties who feel compelled to advance society in the economic field need to provide guidance, direction and assistance to residents who are still eager to work in order to increase their incomes.
Keywords: Work Ethic; Poor Families; Families Economy
Submission to the United Nations Special Rapporteur on the human rights to safe drinking water and sanitation during his Official Visit to Canada
Authors: Campbell-Duruflé Christopher 
Published: April 2024

<p>Canada’s record on climate action has been the object of a long line of criticism. Your visit and ongoing engagement with Canada provide a momentous opportunity to 1) highlight how this inadequate climate action threatens the human rights to safe drinking water and sanitation in Canada, in particular insofar as disadvantaged groups are concerned, 2) highlight how this inadequate climate action also threatens the human rights to safe drinking water and sanitation outside of Canada, also with a differential impact on disadvantaged groups, and 3) call for effective mitigation and adaptation action aligned with Canada’s international obligations. After providing an overview of Canada’s climate record, I discuss all three issues. </p>
<p><em><strong>April 11, 2024</strong></em></p>
تأثير برنامج نفسي بإستخدام الاستراتيجيات المعرفية في الذات المدركة للاعبات كرة السلة في اقليم كوردستان - العراق
Authors: Soran Burhan Muhammad  , Prof. Dr. Ali Qadir Othman  
Published: April 2024

الملخص
يهدف البحث الى اعداد برنامج نفسي للاستراتيجيات المعرفية ، وبناء مقياس للذات المدركة للاعبات كرة السلة للاندية درجة ممتاز في اقليم كوردستان العراق. والتعرف على درجة اللاعبات في مقياس الذات المدركة تم تحديد مجتمع البحث من لاعبات كرة السلة لأندية أقليم كوردستان لموسم 2021 – 2022 وعددهن (7) أندية بواقع (105) لاعبات ، أما عينة البحث التجريبية فقد تم اختيارها وفق أدنى درجة في الوسط الحسابي في المقياس وحسب رآي الخبراء والمختصن في هذا المجال وهو نادي دربنديخان الرياضي بكرة السلة ، واستخدم الباحثان المنهج التجريبي وبتصميم المجموعة الواحدة ذات القياس القبلي والبعدي وذلك لملاءمته لطبيعة مشكلة البحث ، بعد تحليل النتائج استخدم الباحثان الحقيبة الاحصائية (spss) للحصول على النتائج ، حيث ظهرت بعض النتائج امتلاك لاعبات كرة السلة للدرجة الممتازة الكفاءة الذاتية المدركة. و أن الكفاءة الذاتية المدركة يمكن الوصول إليها عن طريق خوض المنافسات ومعرفة مدى كفاءة اللاعبات من خلال النتائج التي يصلون اليها ، ويوصي الباحث الاهتمام من قبل المدربين بقياس الكفاءة الذات المدركة للاعبات كونها تعبر عن مدى رضاهم الذاتي عن قدراتهم ، والاهتمام باللاعبين واجراء الاختبارات النفسية بين فترة واخرى لكونها تساهم في تقويم وتطوير اللاعبين نحو الافضل .
Content On Active Ageing In University Degrees: A Study In Spain And Portugal
Authors: Moreno-Sánchez Emilia , Gago-Valiente Francisco-Javier , Mendoza-Sierra María-Isabel , Sáez-Padilla Jesús , Castillo-Viera Estefania , Campos-de-Sousa-Faria María-Cristina , Lozano-Carvalhal Sandra-Rebeca , Justo-Henriques Susana-Isabel , Martins-Texeira-Da-Costa Emilia-Isabel , Gouveia-Baltazar María-José , Da-Costa-Bizarro-Morais Diana-María 
Published: April 2024

Background: to analyse the study plans of undergraduate and postgraduate degrees at the University of Huelva (Spain), the Beja Polytechnic Institute (Portugal) and the Algarve University (Portugal), to identify content on attention to diversity, ageing and the four pillars of the World Health Organisation for this population (health, safety, continuous learning, and participation). Methods: a methodology was carried out mixed research, in the first place a quantitative phase of data analysis was carried out, for which the statistical program SPSS was used for the observation of frequencies and percentages. In the second phase of the work, and in a qualitative way, carried out an analysis of the content of the program collected in the syllabuses. Results: of the total of the 54 degrees analysed, content related to active aging or, the 4 basic pillars that the WHO comments to address it, were only found in a visible way in the degrees related to the disciplines of Physical Activity, Psychology, Social Sciences, Gerontology, Nursing, and Special Education. Conclusions: this work shows that there is a lack of content on care for ageing in many university degrees that enables students to work with this specific population group. This analysis led to the conclusion that many professionals who have contact with the senior population do not receive the necessary training to respond to the particular needs of individuals in this age group.
Nomenclatura y vocabulario del recurso micológico con importancia biocultural de la cultura mazateca en Oaxaca, México
Authors: Ríos-García Uzziel , Martínez-Reyes Magdalena , Carrera-Martínez Anaitzi , Hernández-Santiago Faustino , Díaz-Aguilar Irma , Leyva-López José C. , Cházarez-Vargas Feliciano , Pérez-Moreno Jesús 
Published: April 2024

Antecedentes: Los estudios etnomicológicos realizados en la región mazateca, al norte del estado de Oaxaca, México, se han enfocado principalmente a especies del género Psilocybe por su importancia ceremonial y de sanación entre los mazatecos de la parte alta. En contraste, el conocimiento y las percepciones locales del uso de otras especies con importancia biocultural y vocablos relacionados a las especies fúngicas, han recibido escasa atención.
Objetivo: Registrar los vocablos y nomenclatura local relacionada con las especies fúngicas con importancia biocultural para los habitantes de la comunidad mazateca de Eloxochitlán de Flores Magón, estado de Oaxaca.
Metodología: Se realizaron entrevistas estructuradas, semiestructuradas y no estructuradas, recorridos y recolectas de material fúngico en campo durante la época de lluvia de 2017 al 2021.
Resultados y conclusiones: Se registraron 116 vocablos relacionados con el recurso micológico en la comunidad desde la cosmovisión mazateca. Dicha nomenclatura se asocia a 27 especies de hongos silvestres con importancia biocultural en la comunidad de estudio. Este estudio documenta que un rico conocimiento micológico pervive a pesar de los fuertes procesos de transculturación a los cuales actualmente es sometida la comunidad mazateca.
The symmetric and asymmetric effect of financial development on ecological footprint in South Africa: ARDL and NARDL approach
Authors: Khoza Sibusiso , Biyase Mduduzi 
Published: April 2024

Introduction: The literature on the finance–emission nexus offers conflicting conclusions. This study resolves this inconsistency by investigating the symmetric and asymmetric effect of financial development on ecological footprint in South Africa, using the Environmental Kuznets Curve framework as a guide. Given the coexistence of ecological deficits and world-class financial development systems in South Africa, it is essential to explore and evaluate potential solutions to mitigating these deficits. Our empirical analysis contributes to the body of literature on the impact of financial development and ecological footprint by using a comprehensive measure of financial development and disaggregates it into its sub-indices to provide a nuanced analysis.Method: This study employs the linear auto regressive distribution lag and nonlinear auto regressive distribution lag techniques to explore the complex interactions of financial development and ecological footprint.Results and Discussion: The findings of this research indicate that financial markets and institutions seem to have varying effects on the ecological footprint. Financial market indices promote environmental quality, while financial institutions exacerbate environmental quality. These results call for policymakers to craft a watertight process that will encourage both financial markets and institutions to allocate capital to projects that are pro-environmental.
Adaptation responses of different ecotypes of Leymus chinensis to saline–alkaline stress
Authors: Li Ya-Xiao , Ma Hong-Yuan , Ni Hong-Wei , Li Shao-Yang , Xu Lu , Sun Meng-Dan , Qi Wen-Wen , Zhao Dan-Dan 
Published: April 2024

IntroductionSoil salinity–alkalinity has emerged as a global problem affecting many ecosystems, including grassland. Plants evolve into different ecotypes to adapt to various environments. Leymus chinensis widely distributed in the eastern Eurasian steppe, has evolved into two main ecotypes: yellow–green(YG) and gray–green (GG). Studies on the adaption mechanisms of both ecotypes in response to saline–alkaline stress are limited.MethodsIn this study, the growth and physiological traits of ecotypes YG and GG in soils with different salinity–alkalinity levels—severe saline–alkaline soil (SS), moderate saline–alkaline soil (MS), and light saline–alkaline soil (LS)—were studied. After exposure to saline–alkaline stress for 15 months, the L. chinensis ecotypes exhibited significant differences in the growth characteristics.ResultsThe specific leaf area, individual tiller biomass, net photosynthetic rate, and potassium content of the two ecotypes under MS conditions were significantly higher than or similar to those under LS conditions. This indicates that L. chinensis showed a certain degree of tolerance to saline–alkaline environments under MS conditions. Saline–alkaline stress increased the tillers by 56% in GG and reduced them by 26% in YG, and did not alter the SLA and the number of individual tiller leaves of GG but reduced that of YG. Moreover, with increasing levels of saline–alkaline stress, ecotype GG exhibited an increase in net photosynthetic rate (Pn), while ecotype YG showed insignificant changes. Under SS, GG exhibited higher Pn and chlorophyll content than YG. Additionally, with the increase in the saline–alkaline stress level, the Na+ content increased, but GG exhibited a significantly lower Na+ content than YG. Conversely, the K+ and Ca2+ contents and the K+/Na+ and Ca2+/Na+ ratios decreased, but GG exhibited higher values than YG.DiscussionGG reduced Na+ by absorption by increasing tillers. Additionally, GG absorbed more K+ and Ca2+ ions, thereby maintaining higher K+/Na+ and Ca2+/Na+ ratios than YG under saline–alkaline stress. These adaptive strategies enable ecotype GG to grow and maintain normal physiological functions under high saline–alkaline stress. The findings of this study hold practical significance for enhancing the economic and ecological value of saline–alkaline grasslands.
Unraveling the immunogenetic landscape of autism spectrum disorder: a comprehensive bioinformatics approach
Authors: Ma Jieying , Liu Deyang , Zhao Jianzhong , Fang Xiaolu , Bu Dengyin 
Published: April 2024

BackgroundAutism spectrum disorder (ASD) is a disease characterized by social disorder. Recently, the population affected by ASD has gradually increased around the world. There are great difficulties in diagnosis and treatment at present.MethodsThe ASD datasets were obtained from the Gene Expression Omnibus database and the immune-relevant genes were downloaded from a previously published compilation. Subsequently, we used WGCNA to screen the modules related to the ASD and immune. We also choose the best combination and screen out the core genes from Consensus Machine Learning Driven Signatures (CMLS). Subsequently, we evaluated the genetic correlation between immune cells and ASD used GNOVA. And pleiotropic regions identified by PLACO and CPASSOC between ASD and immune cells. FUMA was used to identify pleiotropic regions, and expression trait loci (EQTL) analysis was used to determine their expression in different tissues and cells. Finally, we use qPCR to detect the gene expression level of the core gene.ResultsWe found a close relationship between neutrophils and ASD, and subsequently, CMLS identified a total of 47 potential candidate genes. Secondly, GNOVA showed a significant genetic correlation between neutrophils and ASD, and PLACO and CPASSOC identified a total of 14 pleiotropic regions. We annotated the 14 regions mentioned above and identified a total of 6 potential candidate genes. Through EQTL, we found that the CFLAR gene has a specific expression pattern in neutrophils, suggesting that it may serve as a potential biomarker for ASD and is closely related to its pathogenesis.ConclusionsIn conclusion, our study yields unprecedented insights into the molecular and genetic heterogeneity of ASD through a comprehensive bioinformatics analysis. These valuable findings hold significant implications for tailoring personalized ASD therapies.
Comparative analysis of whole plant, flower and root extracts of Chamomilla recutita L. and characteristic pure compounds reveals differential anti-inflammatory effects on human T cells
Authors: Lairikyengbam Divya , Wetterauer Bernhard , Schmiech Michael , Jahraus Beate , Kirchgessner Henning , Wetterauer Pille , Berschneider Karina , Beier Verena , Niesler Beate , Balta Emre , Samstag Yvonne 
Published: April 2024

IntroductionChronic inflammation is a hallmark of chronic wounds and inflammatory skin diseases. Due to a hyperactive and prolonged inflammation triggered by proinflammatory immune cells, transitioning to the repair and healing phase is halted. T cells may exacerbate the proinflammatory milieu by secreting proinflammatory cytokines. Chamomilla recutita L. (chamomile) has been suggested for use in several inflammatory diseases, implying a capability to modulate T cells. Here, we have characterized and compared the effects of differently prepared chamomile extracts and characteristic pure compounds on the T cell redox milieu as well as on the migration, activation, proliferation, and cytokine production of primary human T cells.MethodsPhytochemical analysis of the extracts was carried out by LC-MS/MS. Primary human T cells from peripheral blood (PBTs) were pretreated with aqueous or hydroethanolic chamomile extracts or pure compounds. Subsequently, the effects on intracellular ROS levels, SDF-1α induced T cell migration, T cell activation, proliferation, and cytokine production after TCR/CD3 and CD28 costimulation were determined. Gene expression profiling was performed using nCounter analysis, followed by ingenuity pathway analysis, and validation at protein levels.ResultsThe tested chamomile extracts and pure compounds differentially affected intracellular ROS levels, migration, and activation of T cells. Three out of five differently prepared extracts and two out of three pure compounds diminished T cell proliferation. In line with these findings, LC-MS/MS analysis revealed high heterogeneity of phytochemicals among the different extracts. nCounter based gene expression profiling identified several genes related to T cell functions associated with activation and differentiation to be downregulated. Most prominently, apigenin significantly reduced granzyme B induction and cytotoxic T cell activity.ConclusionOur results demonstrate an anti-inflammatory effect of chamomile- derived products on primary human T cells. These findings provide molecular explanations for the observed anti-inflammatory action of chamomile and imply a broader use of chamomile extracts in T cell driven chronic inflammatory diseases such as chronic wounds and inflammatory skin diseases. Importantly, the mode of extract preparation needs to be considered as the resulting different phytochemicals can result in differential effects on T cells.
Maternal anemia and red blood cell requirements in 72 women undergoing ex-utero intrapartum treatment (EXIT) procedure
Authors: Kloka Jan Andreas , Jasny Thomas , Jennewein Lukas , Friedrichson Benjamin , Zacharowski Kai , Neef Vanessa 
Published: April 2024

BackgroundThe ex-utero intrapartum treatment (EXIT) allows to ensure fetal airway while keeping uteroplacental circulation. However, EXIT may become a life-threatening procedure due to the increased risk of uterine atony or placenta abruption with increased peripartum blood losses and increased transfusion rates. We aim to review maternal anemia prevalence and transfusion requirements in women undergoing EXIT procedure.MethodsUsing data from the Federal German Statistical Office hospitalized women undergoing EXIT procedure between January 1st 2006 and December 31st 2021 were included. The prevalence of anemia, peripartum hemorrhage, comorbidities and administration of red blood cells (RBC) were analyzed.ResultsIn total, 72 women underwent EXIT procedure with a median age of 31 years (26;33.5). In 43.1% EXIT was conducted at 34–36 weeks of gestational age. “Anemia during pregnancy” was present in 47.2%, “anemia due to acute bleeding” in 25.0% and “iron deficiency anemia” in 15.3%. Postpartum hemorrhage occurred in 11.1%. RBCs were transfused in 15.3% of all women. Most women required 1–5 units of RBCs.ConclusionDespite the rarity of this procedure, anemia management and blood conservation strategies in order to reduce the need for RBC transfusion are highly important in women undergoing EXIT procedure.
Diagnostic accuracy of circulating miRNAs to discriminate hepatocellular carcinoma from liver cirrhosis: a systematic review and meta-analysis
Authors: Alemayehu Ermiyas , Belete Melaku Ashagrie , Walle Muluken , Getu Fasil , Mulatie Zewudu , Teshome Mulugeta , Anley Denekew Tenaw , Weldehanna Daniel Gebretsadik , Gedefie Alemu , Ebrahim Hussen 
Published: April 2024

IntroductionHepatocellular carcinoma (HCC) and liver cirrhosis (LC) stand as the primary causes of global mortality. Given their profound impact, the development of highly sensitive and specific circulating diagnostic markers becomes imperative to effectively identify and differentiate between cirrhosis and HCC. Accurate diagnosis is paramount in guiding appropriate therapeutic interventions. Hence, this study aimed to evaluate the potential of microRNAs (miRNAs) in discerning between HCC and LC.MethodsThis study followed the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, with the protocol officially registered on PROSPERO under the reference number CRD42023417494. A thorough search across multiple databases like PubMed, Embase, Scopus, Wiley Online Library, and Science Direct was conducted to identify relevant studies published from January 1, 2018, to August 10, 2023. The included studies underwent methodological quality assessment using the Quality Assessment of Diagnostic Accuracy Studies 2 (QADAS-2) tool. The synthesis of pooled sensitivity, specificity, and other relevant diagnostic parameters employed a random-effects model and was conducted using Stata 14.0. Heterogeneity was assessed using I2 and Cochrane Q, with subsequent subgroup analysis and meta-regression performed to identify potential sources of observed heterogeneity. A sensitivity analysis was performed to assess the resilience of the findings. Furthermore, Deeks’ funnel plot was employed to evaluate publication bias.ResultsIn this meta-analysis, we included fifteen publications, encompassing 787 HCC patients and 784 LC patients. The combined sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the curve (AUC) values of miRNAs in differentiating HCC from LC were 0.84 (95% CI: 0.78–0.88), 0.79 (95% CI: 0.73–0.84), 3.9 (95% CI: 3.0–5.2), 0.21 (95% CI: 0.14–0.29), 19.44 (95% CI: 11–34), and 0.88 (95% CI: 0.85–0.91), respectively. The results of the subgroup analysis revealed that upregulated miRNA levels and miRNA assessments specifically for individuals of European descent exhibited superior diagnostic performance.ConclusionThe results of this study suggested that circulating miRNAs, especially those that are upregulated, have the potential to function as robust and promising biomarkers in the differentiation of HCC from LC.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023475954.
A smartphone application to enhance bowel preparation for first-time colonoscopy: a randomized controlled study
Authors: Pattarapuntakul Tanawat , Kanchanasuwan Thanyaporn , Kaewdech Apichat , Wong Thanawin , Netinatsunton Nisa , Chalermsuksant Nalerdon , Sripongpun Pimsiri 
Published: April 2024

Background and aimsColonoscopy is an essential cancer screening tool; however, bowel preparation is a multifaceted process that involves several steps. Proper preparation is crucial for a successful colonoscopy in terms of diagnostic accuracy and procedural safety. We evaluated the performance of a smartphone application with bowel preparation instructions on individuals undergoing their first colonoscopy.MethodsIn this randomized, prospective, endoscopist-blinded study, participants were scheduled to undergo their first colonoscopy between January 2020 and January 2022. The study protocol was registered at Thai Clinical Trials Registry (TCTR20190928002). They were randomly assigned to the smartphone education application (APP) or the standard education (control) group. The Boston Bowel Preparation Scale (BBPS) score, polyp detection rate (PDR), and adenoma detection rate (ADR) were compared. Factors associated with excellent bowel preparation were also evaluated.ResultsIn total, 119 patients (APP group, n = 57; control group, n = 62) underwent their first colonoscopy. The mean BBPS score and proportion of excellent bowel preparation (BBPS≥8) were significantly higher in the APP group than in the control group. Smartphone application-guided bowel preparation achieved a higher proportion of adequate and excellent bowel preparation scores, was associated with other quality indicators, and achieved the target ADR, cecal intubation rate, and adequate withdrawal time.ConclusionThis application may be a user-friendly option to improve the first-time colonoscopy experience, resulting in effective screening of colorectal cancer.Clinical trial registrationThe study protocol was registered at Thai Clinical Trials Registry (TCTR20190928002).