bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: “Design” of Boron‐Based Compounds as Pro‐Nucleophiles and Co‐Catalysts for Indium(I)‐Catalyzed Allyl Transfer to Various Csp3‐Type Electrophiles.
Authors: Dao Hai Thanh , Schneider Uwe , Kobayashi Shu 
Published: December 2011

AbstractAn improved methodology for the indium(I)‐catalyzed allylation of acetals and ethers, through combination of allyl boronate as pro‐nucleophile with a commercially available borinic ester as co‐catalyst, is reported.
ChemInform Abstract: Oxidative Photodecarboxylation of α‐Hydroxycarboxylic Acid Derivatives with FSM‐16 under Visible Light Irradiation of Fluorescent Lamp.
Authors: Tada Norihiro , Matsusaki Yoko , Miura Tsuyoshi , Itoh Akichika 
Published: December 2011

AbstractFor the first time, FSM‐16 acts as photocatalyst under visible light in the presented synthesis.
ChemInform Abstract: Lewis Base Assisted Broensted Base Catalysis: Direct Regioselective Asymmetric Vinylogous Alkylation of Allylic Sulfones.
Authors: Jiang Lin , Lei Qian , Huang Xin , Cui Hai‐Lei , Zhou Xue , Chen Ying‐Chun 
Published: December 2011

AbstractThe in situ generation of the tert‐butoxy anion as a strong Broensted base by reaction of the amine catalyst with the Morita—Baylis—Hillman carbonates is crucial for generation of the hard nucleophiles.
ChemInform Abstract: Reactions of Dimethyl Carbonate with Aliphatic Amines under High Pressure.
Authors: Margetic Davor , Zrinski Irena , Glasovac Zoran , Eckert‐Maksic Mirjana , Maksimovic Ljiljana 
Published: December 2011

AbstractA catalyst‐free and solvent‐free high‐pressure synthesis of carbamates is described.
ChemInform Abstract: Regio‐ and Stereoselective Synthesis of Multisubstituted Olefins and Conjugate Dienes by Using α‐Oxo Ketene Dithioacetals as the Building Blocks.
Authors: Jin Weiwei , Du Wangming , Yang Qin , Yu Haifeng , Chen Jiping , Yu Zhengkun 
Published: December 2011

AbstractThe method provides an efficient and selective approach to various trisubstituted alkenes and dienes.
ChemInform Abstract: An Efficient Enzymatic Approach to (S)‐1‐Aryl‐allylamines.
Authors: Knezevic Anamarija , Landek Goran , Dokli Irena , Vinkovic Vladimir 
Published: December 2011

AbstractA range of enantiopure aryl allylamines is prepared by optical resolution with Novozym 435.
ChemInform Abstract: Cobalt(II)‐Catalyzed Asymmetric Hydrosilylation of Simple Ketones Using Dipyridylphosphine Ligands in Air.
Authors: Yu Feng , Zhang Xi‐Chang , Wu Fei‐Fei , Zhou Ji‐Ning , Fang Wenjun , Wu Jing , Chan Albert S. C. 
Published: December 2011

AbstractThe applied XPP‐ligand is commercially available and air‐stable.
ChemInform Abstract: Synthesis of 1,2‐Diarylnaphthalenes by Chemoselective Suzuki—Miyaura Reactions of 2‐Bromo‐1‐(trifluoromethanesulfonyloxy)naphthalene.
Authors: Hassan Zahid , Hussain Munawar , Langer Peter 
Published: December 2011

AbstractThe reactions of naphthalene derivative (I) proceed with excellent chemoselectivity in favor of the bromide position allowing the selective formation of diarylated products (V).
ChemInform Abstract: Highly Enantioselective Synthesis of γ‐Substituted Butenolides via the Vinylogous Mukaiyama—Michael Reaction Catalyzed by a Chiral Scandium(III)‐N,N′‐dioxide Complex.
Authors: Zhang Qi , Xiao Xiao , Lin Lili , Liu Xiaohua , Feng Xiaoming 
Published: December 2011

AbstractThe e.e.
ChemInform Abstract: Direct Arylation of Pyrrole Derivatives in Superbasic Media.
Authors: Vakuliuk Olena , Koszarna Beata , Gryko Daniel T. 
Published: December 2011

AbstractOptimized conditions allow the regioselective preparation of 2‐arylpyrroles as important building blocks with the use of aryl iodides and without the external addition of a transition metal catalyst.
ChemInform Abstract: Highly Effective Asymmetric Hydrogenation of Cyclic N‐Alkyl Imines with Chiral Cationic Ru‐MsDPEN Catalysts.
Authors: Chen Fei , Ding Ziyuan , Qin Jie , Wang Tianli , He Yanmei , Fan Qing‐Hua 
Published: December 2011

AbstractThe Ru complex efficiently promotes the process.
ChemInform Abstract: Fused Indolines by Palladium‐Catalyzed Asymmetric C—C Coupling Involving an Unactivated Methylene Group.
Authors: Nakanishi Masafumi , Katayev Dmitry , Besnard Celine , Kuendig E. Peter 
Published: December 2011

AbstractA chiral palladium complex generated from N‐heterocyclic carbene is successfully applied to the synthesis of highly enantioenriched trans‐fused indolines.
ChemInform Abstract: Unexpected Formation of Fluorine‐Containing Tetrahydrocarbazole During the Reaction of Indole, Paraformaldehyde, and Fluorine‐Containing β‐Ketoesters.
Authors: Pang Wan , Xin Yong , Zhu Shi‐fa , Jiang Huan‐feng , Zhu Shi‐zheng 
Published: December 2011

AbstractA three‐component reaction of indole derivatives (I) and (VII), fluorinated β‐ketoesters (II) and (VIII) or β‐ketosulfone (V), and paraformaldehyde is used to prepare a variety of fluorine‐containing indole derivatives.
ChemInform Abstract: Original Synthesis of 2‐Substituted‐4,11‐dimethoxy‐1‐(phenylsulfonyl)‐2,3‐dihydro‐1H‐naphtho [2,3‐f]indole‐5,10‐diones Using TDAE and Cu‐Catalyzed Reaction Strategy.
Authors: Khoumeri Omar , Giuglio‐Tonolo Gamal , Crozet Maxime D. , Terme Thierry , Vanelle Patrice 
Published: December 2011

AbstractA novel rapid synthesis of title naphthoindolediones (IV) is presented, involving TDAE‐mediated reaction of benzylimines with bromomethylanthracenediones (I) followed by Cu‐catalyzed intramolecular amination reaction.
ChemInform Abstract: I‐MCR—Ullmann Cascade Toward Furo[2,3‐b]indole Scaffold.
Authors: Zhu Xu , Xu Xiao‐Ping , Sun Chang , Chen Tao , Shen Zhi‐Liang , Ji Shun‐Jun 
Published: December 2011

AbstractThe synthesis of a variety of title furoindole derivatives, e.g. (V) and (VIII), is presented, involving a three‐component coupling of 1,3‐diketones with o‐halobenzaldehydes and isocyanides, followed by intramolecular Cu‐catalyzed Ullmann reaction.
ChemInform Abstract: Pd‐Catalyzed Direct 5‐Arylation of 1‐Methylpyrazole with Aryl Bromides.
Authors: Beladhria Anissa , Beydoun Kassem , Ammar Hamed Ben , Salem Ridha Ben , Doucet Henri 
Published: December 2011

Abstract1‐Methylpyrazole is arylated under Pd‐catalyzed conditions with aryl bromides to produce mixtures of 4‐ and 5‐substituted products with a preference of the latter.
ChemInform Abstract: Direct Access to 3‐Aminoindazoles by Buchwald—Hartwig C—N Coupling Reaction.
Authors: Lohou Elodie , Collot Valerie , Stiebing Silvia , Rault Sylvain 
Published: December 2011

AbstractThe synthesis of new protected 3‐haloindazoles (II) and (VII) is developed and their efficiency in Buchwald—Hartwig‐type amination is investigated.
ChemInform Abstract: α‐Thioureidoalkylation of 4‐Alkyl‐ and 4‐Phenylthiosemicarbazides.
Authors: Gazieva G. A. , Struchkova M. I. , Kolotyrkina N. G. 
Published: December 2011

AbstractThe title reaction provides previously unknown bis(thiosemicarbazido)imidazolidine‐2‐thiones (III) in good yield.
ChemInform Abstract: A Facile Synthesis of 1,5‐Disubstituted‐2‐aminoimidazoles: Antibiotic Activity of a First Generation Library.
Authors: Harris Tyler L. , Worthington Roberta J. , Melander Christian 
Published: December 2011

AbstractA library of the title compounds (VIII) (20 examples) is efficiently synthesized from readily available amino acids and aldehydes.
ChemInform Abstract: Microwave‐Assisted Tandem Transformation on an Ionic‐Liquid Support: Efficient Synthesis of Pyrrolo/Pyridobenzimidazolones and Isoindolinone‐Fused Benzimidazoles.
Authors: Thummanagoti Suman , Yellol Gorakh S. , Sun Chung‐Ming 
Published: December 2011

AbstractThe title tandem process consists of three steps: condensation followed by successive double intramolecular cyclizations.
ChemInform Abstract: N‐Heterocyclic Carbene‐Catalyzed Rearrangements of Vinyl Sulfones.
Authors: Atienza Roxanne L. , Roth Howard S. , Scheidt Karl A. 
Published: December 2011

AbstractThe carbene generated from a triazolium salt and NaOtBu catalyzes the rearrangement of 1,1‐bis(arylsulfonyl)ethenes to the corresponding (E)‐1,2‐bis(arylsulfonyl)ethenes.
ChemInform Abstract: Divergent Synthesis of Fully Substituted Isoxazoles and Spirofused Pyrazolin‐5‐ones from Cyclopropyl Oximes.
Authors: Fu Xiaolan , Huang Peng , Zhou Guangyuan , Hu Yinqiao , Dong Dewen 
Published: December 2011

AbstractReaction of cyclopropyl oximes under Appel conditions (CBr4, PPh3) provides access to substituted isoxazoles (II) and (V) via cyclopropyl ring opening and recyclization.
ChemInform Abstract: Synthesis of Various Chiral 1,2,4‐Triazole‐Containing α‐Amino Acids from Aspartic or Glutamic Acids.
Authors: Blayo Anne‐Laure , Brunel Frederic , Martinez Jean , Fehrentz Jean‐Alain 
Published: December 2011

AbstractThe starting materials are readily prepared from the corresponding protected amino acids by amide formation and treatment with Lawesson′s reagent.
ChemInform Abstract: Highly Controlling Selectivity of Copper(I)‐Catalyzed Azide/Alkyne Cycloaddition (CuAAC) Between Sulfonyl Azides and Normal Alkynes or Propynoates.
Authors: Liu Yantao , Wang Xinyan , Xu Jimin , Zhang Qun , Zhao Yi , Hu Yuefei 
Published: December 2011

AbstractReaction of terminal alkynes (I) with sulfonyl azides (II) proceeds smoothly in the presence of a Cu(II)—o‐aminophenol catalytic system to give N‐sulfonyltriazoles (III) in good yields.
ChemInform Abstract: Step‐Economic, Efficient, ZnS Nanoparticle‐Catalyzed Synthesis of Spirooxindole Derivatives in Aqueous Medium via Knoevenagel Condensation Followed by Michael Addition.
Authors: Dandia Anshu , Parewa Vijay , Jain Anuj Kumar , Rathore Kuldeep S. 
Published: December 2011

AbstractThe preparation of the ZnS nanoparticles is described as well.
ChemInform Abstract: Enantiospecific Synthesis of Pyridinones as Versatile Intermediates Toward Asymmetric Piperidines.
Authors: Gouault Nicolas , Le Roch Myriam , Cheignon Adele , Uriac Philippe , David Michele 
Published: December 2011

AbstractTreatment of amino ynones of type (I), generated from amino acids, with the system AuCl(PPh3)/AgSbF6 allows a new, simple, and enantioselective access to pyridinones like (IV).
ChemInform Abstract: Furan Ring Opening — Pyridine Ring Closure: New Route to Quinolines under the Bischler—Napieralski Reaction Conditions.
Authors: Butin Alexander V. , Tsiunchik Fatima A. , Kostyukova Olga N. , Uchuskin Maxim G. , Trushkov Igor V. 
Published: December 2011

AbstractA principally new method for the synthesis of polyfunctional title compounds is developed by recyclization of 2‐[2‐(acylamino)benzyl]furans in the presence of POCl3.
ChemInform Abstract: Asymmetric Aza‐[3 + 3] Annulation in the Synthesis of Indolizidines: An Unexpected Reversal of Regiochemistry.
Authors: Buchanan Grant S. , Dai Huifang , Hsung Richard P. , Gerasyuto Aleksey I. , Scheinebeck Casi M. 
Published: December 2011

AbstractTreatment of pyrrolidines of type (I) with enals in the presence of the chiral ammonium salt allows a diastereo‐ and enantioselective access to indolizidines via an unprecedented head—to—tail annulation.
ChemInform Abstract: Rh1‐Catalyzed [6 + 2] Cycloaddition of Alkyne—Allenylcyclobutanes: A New Entry for the Synthesis of Bicyclo[6.m.0] Skeletons.
Authors: Inagaki Fuyuhiko , Sugikubo Katsuya , Oura Yuki , Mukai Chisato 
Published: December 2011

AbstractCleavage of the unfunctionalized simple cyclobutane and construction of the bicyclo[6.m.0] frameworks can be achieved under mild conditions.
ChemInform Abstract: Facile Synthesis of Pyrimidine—Isoxazoline Hybrids in a [bmim][PF6]—Water Biphasic System.
Authors: Lanjewar Kushal , Rahatgaonkar Anjali , Chorghade Mukund , Saraf Binda 
Published: December 2011

AbstractThe solvent system is effective in enhancing the cyclocondensation of enones of type (I)/(III) with hydroxylamine to yield isoxazolines in a short reaction time.
ChemInform Abstract: Synthesis, Molecular Modeling and Bioevaluation of Cycloalkyl Fused 2‐Aminopyrimidines as Antitubercular and Antidiabetic Agents.
Authors: Tripathi Rama Pati , et al. et al. 
Published: December 2011

AbstractA variety of title compounds (III) (20 examples) are efficiently obtained by reaction of bis‐benzylidene cycloalkanones and guanidine hydrochloride.
ChemInform Abstract: Diels—Alder Cycloaddition of Chiral Nonracemic 2,5‐Diketopiperazine Dienes.
Authors: Morris Erin N. , Nenninger E. Katherine , Pike Robert D. , Scheerer Jonathan R. 
Published: December 2011

AbstractSubstrate (II) undergoes regio‐ and stereoselective cycloadditions with electron‐rich and electron‐poor alkenes to afford bicyclo[2.2.2]diazaoctane skeletons.
ChemInform Abstract: A Rapid and Facile Method for the General Synthesis of 3‐Aryl Substituted 4,5,6,7‐Tetrahydro[1,2,3]triazolo[1,5‐a]pyrazines and Their Ring Fused Analogues.
Authors: Chowdhury Chinmay , Mukherjee Sanjukta , Chakraborty Biswajit , Achari Basudeb 
Published: December 2011

AbstractThe Boc‐protective group of compound (V) is easily cleaved under acidic conditions.
ChemInform Abstract: A One‐Pot, Non‐Catalytic Approach to 1,2,4‐Benzothiadiazine‐11‐dioxides.
Authors: Cherepakha Artem , Kovtunenko Vladimir O. , Tolmachev Andrey , Lukin Oleg 
Published: December 2011

AbstractCondensation of o‐halobenzenesulfonyl chlorides with amidines and aminopyridine derivatives provides access towards a wide range of title benzthiadiazine dioxides under mild noncatalytic conditions.
ChemInform Abstract: Stereoselective Synthesis of Dihydrothiadiazinoazines and Dihydrothiadiazinoazoles and Their Pyrolytic Desulfurization Ring Contraction.
Authors: Al‐Etaibi Alya , John Elizabeth , Ibrahim Maher R. , Al‐Awadi Nouria A. , Ibrahim Yehia A. 
Published: December 2011

AbstractBase‐promoted reaction of heterocyclic arylideneaminothiones, e.g. (VII) or (XI), with bromoacetates affords trans‐substituted thiadiazines fused to various heterocycles [cf.
ChemInform Abstract: [4 + 2 + 1] Domino Cyclization in Water for Chemo‐ and Regioselective Synthesis of Spiro‐Substituted Benzo[b]furo[3,4‐e][1,4]diazepine Derivatives.
Authors: Cheng Chuang , Jiang Bo , Tu Shu‐Jiang , Li Guigen 
Published: December 2011

AbstractAll products are purified by being merely filtered and then washed with ethanol.
ChemInform Abstract: Macrocyclization of Oxetane Building Blocks with Diazocarbonyl Derivatives under Rhodium(II) Catalysis.
Authors: Rix Diane , Ballesteros‐Garrido Rafael , Zeghida Walid , Besnard Celine , Lacour Jerome 
Published: December 2011

AbstractThe title reaction affords a rare type of 15‐membered polyether macrocycle.
ChemInform Abstract: Functionalized 3(2H)‐Furanones via Photooxygenation of (β‐Keto)‐2‐substituted Furans: Application to the Biomimetic Synthesis of Merrekentrone C.
Authors: Gryparis Charis , Lykakis Ioannis N. , Efe Christina , Zaravinos Ioannis‐Panayotis , Vidali Theonymphi , Kladou Eugenia , Stratakis Manolis 
Published: December 2011

AbstractMembers of the hygrophorone family like merrekentrone C (VIII), which exhibits fungicidal activity, are prepared using cross coupling of furans (V) and (VI) and photooxygenation of product (VII) as the key steps.
ChemInform Abstract: seco‐Limonoids and Quinoline Alkaloids from Raputia heptaphylla and Their Antileishmanial Activity.
Authors: Coy Barrera Carlos Andres , Coy Barrera Ericsson David , Granados Falla Diana Susana , Delgado Murcia Gabriela , Cuca Suarez Luis Enrique 
Published: December 2011

AbstractThe novel seco‐limonoid raputiolide (I) and the new quinoline alkaloids heptaphyllone A (II) and B (III) are isolated together with six known compounds.
ChemInform Abstract: Design, Synthesis and Evaluation of New α‐Nucleophiles for the Hydrolysis of Organophosphorus Nerve Agents: Application to the Reactivation of Phosphorylated Acetylcholinesterase.
Authors: Saint‐Andre Geraldine , Kliachyna Maria , Kodepelly Sanjeevarao , Louise‐Leriche Ludivine , Gillon Emilie , Renard Pierre‐Yves , Nachon Florian , Baati Rachid , Wagner Alain 
Published: December 2011

AbstractA variety of (het)aryl aldoximes, (het)arylamidoximes and hydroxamic acids, e.g. (I), is tested as nucleophilic agent for the hydrolysis of phenylphosphonothioate (PhX), a member of a class of organophosphorus used as chemical warfare agents.
DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67‐positive neurons in the GAD67‐GFP mouse brain
Authors: Kadriu Bashkim , Guidotti Alessandro , Chen Ying , Grayson Dennis R. 
Published: December 2011

AbstractDNA methylation is an epigenetic regulatory mechanism commonly associated with transcriptional silencing. DNA methyltransferases (DNMTs) are a family of related proteins that both catalyze the de novo formation of 5‐methylcytosine and maintain these methylation marks in cell‐specific patterns in virtually all mitotic cells of the body. In the adult brain, methylation occurs in progenitor cells of the neurogenic zones and in postmitotic neurons. Of the DNMTs, DNMT1 and DNMT3a are most highly expressed in postmitotic neurons. While it has been commonly thought all postmitotic neurons and glia express DNMTs at comparable levels, the coexpression of selected DNMTs with markers of distinct neurotransmitter phenotypes has not been previously examined in detail in the mouse. To this end, we analyzed the expression of DNMT1 and DNMT3a along with GAD67 in the brains of the glutamic acid decarboxylase67‐enhanced green fluorescent protein (GAD67‐GFP) knockin mice. After first confirming that GFP‐immunopositive neurons were also GAD67‐positive, we showed that in the motor cortex, piriform cortex, striatum, CA1 region of the hippocampus, dentate gyrus, and basolateral amygdala (BLA), GFP immunofluorescence coincided with the signal corresponding to DNMT1 and DNMT3a. A detailed examination of cortical neurons, showed that ≈30% of NeuN‐immunopositive neurons were also DNMT1‐positive. These data do not exclude the expression of DNMT1 or DNMT3a in glutamatergic neurons and glia. However, they suggest that their expression is low compared with the levels present in GABAergic neurons. J. Comp. Neurol. 520:1951–1964, 2012. © 2011 Wiley Periodicals, Inc.
Complexity of networks (Reprise)
Authors: Standish Russell K. 
Published: December 2011

AbstractNetwork or graph structures are ubiquitous in the study of complex systems. Often, we are interested in complexity trends of these system as it evolves under some dynamic. An example might be looking at the complexity of a food web as species enter an ecosystem via migration or speciation, and leave via extinction. In a previous article, a complexity measure of networks was proposed based on the “complexity is information content” paradigm. To apply this paradigm to any object, one must fix two things: a representation language, in which strings of symbols from some alphabet describe, or stand for the objects being considered; and a means of determining when two such descriptions refer to the same object. With these two things set, the information content of an object can be computed in principle from the number of equivalent descriptions describing a particular object. The previously proposed representation language had the deficiency that the fully connected and empty networks were the most complex for a given number of nodes. A variation of this measure, called zcomplexity, applied a compression algorithm to the resulting bitstring representation, to solve this problem. Unfortunately, zcomplexity proved too computationally expensive to be practical. In this article, I propose a new representation language that encodes the number of links along with the number of nodes and a representation of the linklist. This, like zcomplexity, exhibits minimal complexity for fully connected and empty networks, but is as tractable as the original measure. This measure is extended to directed and weighted links, and several real‐world networks have their network complexities compared with randomly generated model networks with matched node and link counts, and matched link weight distributions. When compared with the random networks, the real‐world networks have significantly higher complexity, as do artificially generated food webs created via an evolutionary process, in several well‐known ALife models. © 2011 Wiley Periodicals, Inc. Complexity, 2011
Characterization of volatile and aroma‐impact compounds in persimmon (Diospyros kaki L., var. Triumph) fruit by GC‐MS and GC‐O analyses
Authors: Wang Ying , Hossain Doris , Perry Patrick L. , Adams Bill , Lin Jianming 
Published: December 2011

ABSTRACTAlthough persimmon fruit is grown in various countries and is increasingly appreciated for its nutritional value, health benefits and rich flavour, surprisingly little research has been conducted to uncover the components responsible for its unique flavour. An aroma extract of persimmon fruit (Diospyros kaki L., var. Triumph) was obtained by hydrodistillation under vacuum followed by solid phase extraction. Gas chromatography–mass spectometry (GC‐MS) analysis of the extract led to the positive identification of 50 compounds, among which aldehydes emerged as the most important class of volatile compounds. Thirty‐two compounds were determined to have aroma‐impact, by gas chromatography–olfactometry analysis of the aroma extract. The six most intense aroma‐impact compounds were methional, (E)‐2‐hexenal, phenylacetaldehyde, (E,Z)‐2,6‐nonadienal, hexanal and Furaneol®. Their aroma qualities largely explain the aroma character of persimmon fruit, which was described as fresh peach, a touch of orange, sweet, woody, floral, green and potato. Unambiguous identification of trace aroma‐impact compounds (E,E,Z)‐2,4,6‐nonatrienal and (E,Z,Z)‐2,4,7‐decatrienal by GC‐MS was achieved by applying a solid phase extraction procedure for selective isolation of carbonyl compounds. Copyright © 2011 John Wiley & Sons, Ltd.
Zurich Cross Rail, Weinberg Tunnel – the challenges of the loose ground section and passing under the river / Durchmesserlinie Zürich, Weinbergtunnel – Herausforderung Lockergesteinsstrecke und Flussunterquerung
Authors: Bosshard Martin , Bolliger Josef , Kobel Roland 
Published: December 2011

AbstractA notable increase of rail traffic is expected in Switzerland in the next few decades. In order to cope with this increase, the main station in Zurich is being improved with a new underground through station – the Löwenstraße station. This will be connected to the existing Swiss Railways network through the new Weinberg Tunnel. With the opening of the new Cross Rail in 2014, Zurich will become more attractive as a business location, and the journey times for long‐distance connections will be massively improved. The investment cost of this project is about 2.031 billion CHF (price basis 2005). This article gives an overview of the overall project and then describes the Weinberg Tunnel and the loose ground section in detail.In der Schweiz wird für die kommenden Jahrzehnte eine markante Zunahme des Bahnverkehrs erwartet. Um diese Zunahme bewältigen zu können, wird der Hauptbahnhof Zürich mit einem neuen unterirdischen Durchgangsbahnhof – dem Bahnhof Löwenstraße – erweitert. Dieser soll über den neuen Weinbergtunnel an das bestehende Netz der Schweizerischen Bundesbahnen angeschlossen werden. Mit Inbetriebnahme dieser so genannten Durchmesserlinie im Jahr 2014 gewinnt der Wirtschaftsstandort Zürich an zusätzlicher Attraktivität, aber auch die Reisezeiten im Fernverkehr erfahren massive Verbesserungen. Die Investitionskosten für dieses Projekt belaufen sich auf rund 2,031 Mrd. CHF (Preisbasis 2005). Der Beitrag gibt einen Überblick über das Gesamtprojekt und beschreibt dann eingehend den Weinbergtunnel mit der Lockergesteinsstrecke.