bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcome, general, and symptom‐specific quality of life after various types of parotid resection
Authors: Ciuman Raphael Richard , Oels Wolfgang , Jaussi Rolf , Dost Philipp 
Published: April 2012

AbstractObjectives/Hypothesis:To document the outcome and impact on general and symptom‐specific quality of life (QOL) after various types of parotid resection.Study Design:General and symptom‐specific QOL assessment at least 1 year after performed surgery. Retrospective data and outcome analysis of patients.Methods:Between 2004 and 2010, 353 parotid resections in 337 patients were conducted at the Department of Otorhinolaryngology, University Teaching Hospital, St. Mary's Hospital Gelsenkirchen, Gelsenkirchen, Germany. A total of 196 patients fit the inclusion criteria and were available for postoperative evaluation. The general QOL assessment was based on both the global health status and global QOL scales of the European Organisation for Research and Treatment of Cancer (EORTC) Quality‐of‐Life Questionnaire in 34 patients. Symptom‐specific QOL was assessed with the Parotidectomy Outcome Inventory‐8 (POI‐8). In addition, aesthetic outcome was evaluated with an ordinal scale.Results:Outcome of parotidectomies in benign disease has little impact on general QOL and global health status. However, hypoesthesia or dysesthesia, Frey's syndrome, and cosmetic discontent are quite common and may affect symptom‐specific and general QOL. Correlation with extent of surgery and statistically significant differences of patient evaluation for aesthetic outcome, sensory impairment, and Frey's syndrome between various types of limited parotid surgery (enucleation, extracapsular dissection, partial superficial parotidectomy) and superficial parotidectomy could be shown.Conclusions:An adequate parotid resection technique must be chosen to achieve the least disturbing outcome. In addition, in our patient collective, there was no increased recurrence rate found after limited parotid resection for pleomorphic adenoma or cystadenolymphoma. Laryngoscope, 2012
Reducing nasal morbidity after skull base reconstruction with the nasoseptal flap: Free middle turbinate mucosal grafts
Authors: Kimple Adam J. , Leight W. Derek , Wheless Stephen A. , Zanation Adam M. 
Published: March 2012

AbstractObjectives/Hypothesis:The nasoseptal flap provides hearty vascularized tissue for reconstruction of expanded endonasal approaches (EEA); however, it produces donor site morbidity due to exposed cartilage. Mucosalization of the septum requires 12 weeks, multiple debridements, and frequent saline rinses. This study addresses the reduction of nasal morbidity by grafting middle turbinate mucosa onto the exposed septum.Study Design:Small prospective study with retrospective analysis of a larger cohort.Methods:Fifteen patients undergoing EEA of the ventral skull base were prospectively enrolled. In seven cases, the sacrificed middle turbinate mucosa was harvested and placed as a free mucosal graft on the septal cartilage. In eight controls, middle turbinate grafting was not performed due to tumor involvement. Septal mucosalization and crusting of all patients was quantified at follow‐up appointments. An additional 46 patients were retrospectively identified who received middle turbinate grating on their exposed septal cartilage, and mucosalization rates were determined from clinical records.Results:Three weeks after initial operation, the mucosalization rate was 70% versus 5% in the graft and nongraft groups, respectively. At postoperative week 6, the mucosalization and crusting were 97% and 5% for the graft group versus 60% and 85% for the nongraft group. Mucosalization rates in the retrospective graft series agreed with the prospective series.Conclusions:Despite donor site morbidity, the nasoseptal flap is becoming the standard of care for skull base reconstruction due to its reliability in reestablishing a barrier between the subarachnoid space and the sinonasal tract. It is possible to dramatically increase the rate of septal mucosalization and decrease crusting by using a middle turbinate free mucosal graft. Laryngoscope, 2012
Effects of Strategic Exiting from Sponsorship after Negative Event Publicity
Authors: Messner Matthias , Reinhard Marc‐André 
Published: March 2012

ABSTRACTResearch on the effects of event sponsorship has focused mainly on the consequences for brand equity of the association between a sponsor and a sponsored event. However, the effects of management's decision to exit from a sponsorship have received little empirical consideration. The studies reported here were carried out to fill this gap by systematically examining (a) the impact of a sponsor's corporate reputation on consumer responses to the strategic exit from a controversial sponsorship, and (b) the role that perceived trust in the decision plays in determining the outcomes. The results of two studies emphasize that strategic exiting from a controversial sponsorship (i.e., possible doping scandals at the event) can have positive consequences for the sponsor's image when the decision is trusted, but detrimental consequences when the exiting is attributed to overly self‐serving reasons. Trust in sponsorship withdrawal is elicited when the sponsor is perceived as having a good character with respect to meeting societal obligations, or when communication efforts are made salient that create trust in the withdrawal decision by a firm with a bad character.
A balancing domain decomposition by constraints preconditioner for a weakly over‐penalized symmetric interior penalty method
Authors: Brenner Susanne C. , Park Eun‐Hee , Sung Li‐Yeng 
Published: March 2012

SUMMARYWe develop a balancing domain decomposition by constraints preconditioner for a weakly over‐penalized symmetric interior penalty method for second‐order elliptic problems. We show that the condition number of the preconditioned system satisfies similar estimates as those for conforming finite element methods. Corroborating numerical results are also presented. Copyright © 2012 John Wiley & Sons, Ltd.
A meshfree‐enriched finite element method for compressible and near‐incompressible elasticity
Authors: Wu C.T. , Hu W. , Chen J.S. 
Published: March 2012

SUMMARYIn this paper, a two‐dimensional displacement‐based meshfree‐enriched FEM (ME‐FEM) is presented for the linear analysis of compressible and near‐incompressible planar elasticity. The ME‐FEM element is established by injecting a first‐order convex meshfree approximation into a low‐order finite element with an additional node. The convex meshfree approximation is constructed using the generalized meshfree approximation method and it possesses the Kronecker‐delta property on the element boundaries. The gradient matrix of ME‐FEM element satisfies the integration constraint for nodal integration and the resultant ME‐FEM formulation is shown to pass the constant stress test for the compressible media. The ME‐FEM interpolation is an element‐wise meshfree interpolation and is proven to be discrete divergence‐free in the incompressible limit. To prevent possible pressure oscillation in the near‐incompressible problems, an area‐weighted strain smoothing scheme incorporated with the divergence‐free ME‐FEM interpolation is introduced to provide the smoothing on strains and pressure. With this smoothed strain field, the discrete equations are derived based on a modified Hu–Washizu variational principle. Several numerical examples are presented to demonstrate the effectiveness of the proposed method for the compressible and near‐incompressible problems. Copyright © 2012 John Wiley & Sons, Ltd.
Ternary and multinary Cu‐chalcogenide photovoltaic materials from CuInSe2 to Cu2ZnSnS4 and other compounds
Authors: Wada Takahiro , Nakamura Satoshi , Maeda Tsuyoshi 
Published: March 2012

ABSTRACTSuch ternary and multinary copper chalcogenides (TMCC) as CuInSe2 (CIS) and Cu2ZnSnS4 are suitable as absorber materials for thin‐film solar cells. The valence band consists of Cu 3d and chalcogen p orbitals, and the conduction band consists of III (In) ns or IV (Sn) ns and chalcogen p orbitals. The band structure characteristics of TMCC differ from those of conventional II–VI compounds. The valence band maximum is higher, and the bandgap is narrower than II–VI compounds. Therefore, the electrons in the valence band of TMCC are easily removed, and TMCC tends to be a p‐type semiconductor. This common characteristic of TMCC is one reason that it is suitable as an absorber material in thin‐film solar cells. In CIS, two kinds of chemical bond, Cu–Se and In–Se, exist. Among them, the In–Se bond is much stronger than the Cu–Se bond. This characteristic is advantageous for the “three‐stage process” of high‐quality CIS thin films used in solar cells. However, the characteristics of the other TMCC are not the same as those of CIS. A deposition process of high‐quality TMCC thin films that exploits the characteristics of chemical bonding in TMCC should be developed. Copyright © 2012 John Wiley & Sons, Ltd.
A worldview of the professional experiences and training needs of pediatric psycho‐oncologists
Authors: Wiener Lori , Oppenheim Daniel , Breyer Joanna , Battles Haven , Zadeh Sima , Patenaude Andrea Farkas 
Published: March 2012

AbstractBackgroundThirty years after the origin of the field of psycho‐oncology, limited data exist about the work practices of professionals providing psychosocial care to children with cancer and their families.MethodA survey was designed to assess training, work environment, theoretical orientation, services provided, subspecialty areas or areas of special interest, satisfactions, challenges, and continuing education needs of pediatric psycho‐oncologists. Members of national and international psycho‐oncology organizations were invited to participate in the web‐based survey.ResultsSeven hundred eighty‐six professionals from 63 countries responded. The sample consisted mostly of psychologists (41%), physicians (20%), and social workers (14%). Approximately half of the participants worked in a designated psycho‐oncology unit. Psychologists and social workers provided the majority of psychosocial services. Individual sessions with parents were most common (42%), followed by sessions with children (41%), survivors (36%), families (31%), and siblings (25%). Therapies provided include cognitive behavioral therapy (50%), relaxation (43%), psychodynamic psychotherapy (27%), play therapy (26%), and imagery (23%). Two‐thirds reported having appropriate supervision, 37% were conducting research, and only half felt their salary was appropriate. Differences in therapeutic modalities were found by country. Clinicians desire training on clinical interventions, improving communication with medical staff, research, and ethics.ConclusionsAn international cohort of clinicians providing pediatric psycho‐oncology services perform a wide variety of tasks, use a range of therapeutic approaches, and report considerable work satisfaction. Problem areas include professional inter‐relations, inadequate supervision, and need for additional specialized training. Opportunity exists for global collaboration in pediatric psycho‐oncology research and practices to enhance clinical effectiveness and reduce professional isolation. Copyright © 2012 John Wiley & Sons, Ltd.
Coping in long‐term survivors of childhood cancer: relations to psychological distress
Authors: Wenninger Kerstin , Helmes Almut , Bengel Jürgen , Lauten Melchior , Völkel Susanne , Niemeyer Charlotte M. 
Published: March 2012

AbstractObjectiveThe goal of this study was to describe coping strategies and their associations with psychological distress in young adult survivors of childhood cancer.MethodsOne hundred and sixty‐four childhood cancer survivors, at least 7 years after diagnosis, completed questionnaires assessing demographics, health information, psychological distress, and different ways of coping (return rate: 61%). The Brief Symptom Inventory‐18 (BSI‐18) and the Post‐traumatic Diagnostic Scale's (PDS) eight‐item short form were used to measure psychological distress. Coping was assessed with the Cognitive Control Strategies Scale (CCSS), the Illness Perception Questionnaire‐Revised (IPQ‐R), and the White Bear Suppression Inventory (WBSI).ResultsHigher levels of distress were associated with the female sex, not being in a relationship, and with the presence of medical late effects. These predictors explained 12% of the variance in psychological distress. When coping variables were also entered into the equation, the amount of explained variance increased to 50%. The most important determinants of psychological distress in our sample were a tendency to suppress negative thoughts and a low level of optimism.ConclusionThese results contribute to a better understanding of the correlates of difficulties in long‐term psychological adjustment after childhood cancer. Cognitive strategies, which are associated with or may increase the risk for concurrent psychological distress, in specific, avoidance of negative thoughts and a lack of positive future expectations, should be addressed in psychological counseling with survivors suffering from symptoms of distress. Copyright © 2012 John Wiley & Sons, Ltd.
Characterization of nanoscaled solder material
Authors: Novikov Andrej , Nowottnick Mathias 
Published: March 2012

AbstractThe properties of nanoscaled layers of pure tin have been studied. The layers were produced by sputtering in different thicknesses between 10 and 100 nm. The surface topography and the influence of process parameters on the sputtering rate were characterized using scanning electron microscopy (SEM) and atomic force microscopy (AFM) methods. To avoid oxidation carbon and silicon nitride protective layers were sputtered in the same process chamber. The function of this coating was investigated by X‐ray diffraction (XRD). The crystallographic structure of tin layer under silicon nitride was measured directly after sputtering, melting and cooling processes. The crystalline tin film after cooling down and the absence of tin oxide peaks were used as indicators for impermeability of oxygen. For investigation of phase change the method of chip differential calorimetry (DSC) was used. The samples were prepared as standalone samples for reuse of DSC‐chips and also sputtered directly on the DSC chip for single use. The prepared samples with one tin layer and multilayer of tin scaled down to 10 nm were investigated with this method.
The impact of North Atlantic sea surface temperature errors on the simulation of North Atlantic European region climate
Authors: Keeley S. P. E. , Sutton R. T. , Shaffrey L. C. 
Published: March 2012

AbstractCurrent state‐of‐the‐art climate models fail to capture accurately the path of the Gulf Stream and North Atlantic Current. This leads to a warm bias near the North American coast, where the modelled Gulf Stream separates from the coast further north, and a cold anomaly to the east of the Grand Banks of Newfoundland, where the North Atlantic Current remains too zonal in this region. Using an atmosphere‐only model forced with the sea surface temperature (SST) biases in the North Atlantic, we consider the impact they have on the mean state and the variability in the North Atlantic European region in winter. Our results show that the SST errors produce a mean sea‐level pressure response that is similar in magnitude and pattern to the atmospheric circulation errors in the coupled climate model. The work also suggests that errors in the coupled model storm tracks and North Atlantic Oscillation, compared to reanalysis data, can also be explained partly by these SST errors. Our results suggest that both the error in the Gulf Stream separation location and the path of the North Atlantic Current around the Grand Banks play important roles in affecting the atmospheric circulation. Reducing these coupled model errors could improve significantly the representation of the large‐scale atmospheric circulation of the North Atlantic and European region. Copyright © 2012 Royal Meteorological Society
Genome analysis of the new human polyomaviruses
Authors: Van Ghelue Marijke , Khan Mahmud Tareq Hassan , Ehlers Bernhard , Moens Ugo 
Published: March 2012

SUMMARYPolyomaviridae is a growing family of naked, double‐stranded DNA viruses that infect birds and mammals. The last few years, several new members infecting birds or primates have been discovered, including seven human polyomaviruses: KI, WU, Merkel cell polyomavirus, HPyV6, HPyV7, trichodysplasia spinulosa‐associated polyomavirus, and HPyV9. In addition, DNA and antibodies against the monkey lymphotropic polyomavirus have been detected in humans, indicating that this virus can also infect man. However, little is known about the route of infection, transmission, cell tropism, and, with the exception of Merkel cell polyomavirus and trichodysplasia spinulosa‐associated polyomavirus, the pathogenicity of these viruses. This review compares the genomes of these emerging human polyomaviruses with previously known polyomaviruses detected in man, reports mutations in different isolates, and predicts structural and functional properties of their viral proteins. Copyright © 2012 John Wiley & Sons, Ltd.
Limits of minimal models and continuous orbifolds
Authors: Gaberdiel Matthias R. , Suchanek Paulina 
Published: March 2012

AbstractThe λ = 0 ’t Hooft limit of the 2d$ {\mathcal{W}_N} $minimal models is shown to be equivalent to the singlet sector of a free boson theory, thus paralleling exactly the structure of the free theory in the Klebanov-Polyakov proposal. In 2d, the singlet sector does not describe a consistent theory by itself since the corresponding partition function is not modular invariant. However, it can be interpreted as the untwisted sector of a continuous orbifold, and this point of view suggests that it can be made consistent by adding in the appropriate twisted sectors. We show that these twisted sectors account for the ‘light states’ that were not included in the original ’t Hooft limit. We also show that, for the Virasoro minimal models (N = 2), the twisted sector of our orbifold agrees precisely with the limit theory of Runkel & Watts. In particular, this implies that our construction satisfies crossing symmetry.
Reference values for Doppler velocimetry of the ophthalmic and central retinal arteries in low‐risk pregnancy
Authors: Corrêa‐Silva Eloisa P. , Surita Fernanda G. , Barbieri Cristiane , Morais Sirlei S. , Cecatti José G. 
Published: March 2012

AbstractObjectiveTo establish reference values for Doppler velocimetry of the ophthalmic artery (OA) and the central retinal artery (CRA) in low‐risk pregnancy.MethodBetween January 2008 and March 2009, 63 low‐risk pregnant women underwent an ultrasound scan every 2 weeks at the Women's Hospital, Campinas, Brazil, to determine the resistance index (RI), pulsatility index (PI), and peak systolic velocity of both arteries, in addition to the flow velocity of the second peak and peak ratio (PR) of the OA. For analysis, linear regression was used with mixed models for longitudinal data, coefficient of determination, and estimates of the 5th and 95th percentiles for each parameter at each gestational age. Intra‐ and inter‐observer variability was evaluated via the intraclass correlation coefficient.ResultsThere was a trend of a reduction with gestational age in PI and RI of the OA, and PI of the CRA, but not in PR of the OA; and the respective reference values were established. Intra‐ and inter‐observer variability was considered satisfactory.ConclusionUnilateral assessment of the orbital Doppler velocimetry is feasible. Establishment of reference values showed a negative correlation between gestational age and PI and RI of the OA, and PI of the CRA. The method demonstrated satisfactory reproducibility.
Reno: regularized non-parametric analysis of protein lysate array data
Authors: Li Bin , Liang Feng , Hu Jianhua , He and Xuming 
Published: March 2012

Abstract
Motivation: The reverse-phase protein lysate arrays have been used to quantify the relative expression levels of a protein in a number of cellular samples simultaneously. To avoid quantification bias due to mis-specification of commonly used parametric models, a nonparametric approach based on monotone response curves may be used. The existing methods, however, aggregate the protein concentration levels of replicates of each sample, and therefore fail to account for within-sample variability.
Results: We propose a method of regularization on protein concentration estimation at the level of individual dilution series to account for within-sample or within-group variability. We use an efficient algorithm to optimize an approximate objective function, with a data-adaptive approach to choose the level of shrinkage. Simulation results show that the proposed method quantifies protein concentration levels well. We show through the analysis of protein lysate array data from cell lines of different cancer groups that accounting for within-sample variability leads to better statistical analysis.
Availability: Code written in statistical programming language R is available at: http://odin.mdacc.tmc.edu/~jhhu/Reno
Contact: jhu@mdanderson.org
Supplementary information: Supplementary data are available at Bioinformatics online.
AutoLabDB: a substantial open source database schema to support a high-throughput automated laboratory
Authors: Sparkes Andrew , Clare Amanda 
Published: March 2012

Abstract
Motivation: Modern automated laboratories need substantial data management solutions to both store and make accessible the details of the experiments they perform. To be useful, a modern Laboratory Information Management System (LIMS) should be flexible and easily extensible to support evolving laboratory requirements, and should be based on the solid foundations of a robust, well-designed database. We have developed such a database schema to support an automated laboratory that performs experiments in systems biology and high-throughput screening.
Results: We describe the design of the database schema (AutoLabDB), detailing the main features and describing why we believe it will be relevant to LIMS manufacturers or custom builders. This database has been developed to support two large automated Robot Scientist systems over the last 5 years, where it has been used as the basis of an LIMS that helps to manage both the laboratory and all the experiment data produced.
Availability and implementation: The database schema has been made available as open source (BSD license), so that others may use, extend and improve it to meet their own needs. Example software interfaces to the database are also provided. http://autolabdb.sourceforge.net/
Contact: afc@aber.ac.uk