bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systemic mastocytosis associated with t(8;21) acute myeloid leukemia in a child: Detection of the D816A mutation of KIT
Authors: Yabe Miharu , Masukawa Atsuko , Kato Shunichi , Yabe Hiromasa , Nakamura Naoya , Matsushita Hiromichi 
Published: July 2012

AbstractSystemic mastocytosis (SM) associated with t(8;21) acute myeloid leukemia (AML) is very rare, and the D816 mutation of the KIT gene has previously been detected only in adult patients. We herein report the case of a 5‐year‐old female presenting with AML harboring t(8;21)(q22;q22). Her AML was refractory to chemotherapy, and bone marrow mastocytosis developed simultaneously at the initial diagnosis and during chemotherapy. The D816A mutation of KIT was detected. SM associated with t(8;21) AML, accompanied by a KIT mutation in children may result in a poor prognosis, despite the fact that t(8;21) AML are generally considered to have a favorable risk. Pediatr Blood Cancer 2012; 59: 1313–1316. © 2012 Wiley Periodicals, Inc.
‘TRAVELLING WHILE SITTING DOWN’: MOBILE PHONES, MOBILITY AND THE COMMUNICATION LANDSCAPE IN INHAMBANE, MOZAMBIQUE
Authors: Archambault Julie Soleil 
Published: July 2012

ABSTRACTThis article examines the ways in which young men in the city of Inhambane, southern Mozambique, harness communication to express and address experiences of constrained physical and social mobility. It starts with an analysis of a highly valued form of oral communication –bater papo– that youth, especially young men, engage in on a daily basis before turning to mobile phone use. Tying these different forms of communication together is a profound desire to claim membership of, and to participate in, a world that remains elusive for most. However, if mobile phone communication builds on pre-existent forms of communication, it takes on particular aesthetic qualities that speak of, rather than resolve, exclusion. The article argues that, while helping bridge distances in significant ways, mobile phone communication nonetheless, and somewhat ironically, also betrays young men's immobility.
‘EVERY NAME HAS ITS PATH’: IMAGINING AND ACHIEVING FULBE ENTANGLEMENT IN A MOOSE COMMUNITY
Authors: Breusers Mark 
Published: July 2012

ABSTRACTGiven the observed agro-pastoralization of livelihoods of both Moose ‘farmers’ and Fulbe ‘herdsmen’, interactions between both groups living in Burkina Faso's north-central region are usually interpreted in terms of vanishing symbiosis and increasing tension along ethnic lines. There is, however, a remainder to this equation, namely the cattle Moose entrust to Fulbe. This article looks into Fulbe involvement in solving Moose fecundity problems to elucidate the nature of the relationships in which cattle entrustment is embedded. It is argued that Moose ideas about the other world and its intervention in procreation and constituting personhood allow imagining an extension of Moose societal relations beyond conventional community boundaries, that is, including Fulbe. This extension can be subsequently – but not necessarily – effectuated through the establishment and performance of spiritual kinship in which cattle owned by Moose can be embedded. The divergent extent to which sustained Moose–Fulbe relations result is explained in terms of social controversy regarding agro-pastoralization of livelihoods accompanied by differential cattle accumulation.
Seals in the Inner Hebrides
Authors: Vaughan R. William 
Published: July 2012

SynopsisAbout 10% of the British grey seal population and 20% of the British common seal population breed around the Inner Hebrides. Grey seals occur on the more exposed coasts whereas common seals inhabit the more sheltered waters and the inner reaches of sea lochs. There is some evidence of an increase in grey seal numbers, but there are insufficient data to assess the exact status of the common seal.
Ecology and phytogeographical affinities of the bryophytes in the Inner Hebrides
Authors: Corley M. F. V. 
Published: July 2012

SynopsisOf just under 1000 species of bryophyte known in the British Isles, 597 are recorded in the Inner Hebrides. This diversity of species is due to several factors: the suitability of the climate for bryophyte growth, the rich variety of bryophyte habitats and the presence of several phytogeographical elements in the islands.Bryophyte species occur in varying numbers in almost all habitats from the spray zone at high water mark to the tops of mountains. Compared with the Outer Hebrides and the adjacent mainland, certain bryophytes are absent from the islands. This is largely due to the scarcity of dune slacks in the Inner Hebrides, and the poorer development of high mountain habitats.Examples are given of a number of typical Inner Hebridean habitats together with their characteristic bryophyte species.Naturally the Inner Hebrides are rich in species with an oceanic distribution in the British Isles. These are analysed into groups based on their world distributions. A number of species with strongly disjunctive distributions are thought to be Tertiary relicts in the British flora.A list of the bryophytes recorded in the Inner Hebrides is appended giving presence or absence in each island or group of islands.
Wildfowl of the Inner Hebrides
Authors: Ogilvie M. A. , Atkinson-Willes G. L. 
Published: July 2012

SynopsisWildfowl habitat in the Inner Hebrides. Excluding Islay, consists mainly of sheltered bays and sealoches, while fertile freshwater lochs are uncommon, the best being on Tiree. The known breeding distribution and winter concentrations of species are described and an indication is given of overall status and histroical background. There are very few records from many of the smaller islands, and even those from Skye, Tiree and Mull are restricted to between one and four winters.Eider and red-breasted merganser are probably the two commonest wintering speices, but there are no good estimates of total numbers. Flocks of 500–600 eider occur round Skye, and summer moulting concentrations of 1.400–1.700 merganser in the Sound of Gigha indicate a high pouplation. Between 2.400–2.600 barnacle geese Branta leucopsis spend the winter on many small. Uninhabited islands throughtout the region. Wigcon. Teal, mallard and tufted duck occur in flocks in several places, with maxima between 150 abd 350.Whooper swan Cygnus cygnus, Greenland white-fronted goose Anser albifrons flavirostris, shelduck, shoveler, pochard, goldeneye Bucephala clangula, long-tailed duck Clangula hymelis and goosander all winter regularly, though rarely in flocks of more than 100.
The four faces of organizational culture
Authors: Fortado Bruce , Fadil Paul 
Published: July 2012

PurposeThe purpose of this paper is to compare and contrast four different views of organizational culture. Specifically, it will compare the human relations view of culture with three more “modern” perspectives to determine whether the meaning and the research methods associated with this phenomenon has shifted over time.Design/methodology/approachEach face of organizational culture research (human relations; software of the mind; process consultation; and appreciative inquiry) are described and critiqued. Methods utilized by researchers in their respective eras are compared and contrasted.FindingsIn comparing the human relations approach to defining and researching organizational culture with the three more modern faces, one thing has become apparent: the meaning of culture, over time, has changed. It has become less a permanent, manifested phenomena, and more of a manipulable asset. It is assumed that cultures can be molded quickly and easily into whatever the organizations need. Additionally, the methods for researching organizational culture today are much shallower, as surveys continue to replace in‐depth interviews and long‐term observations. The multidimensional levels of culture require researchers to explore this phenomenon's varying depths, not just at the shallowest plane.Research limitations/implicationsThe main research contribution of this article is that it is a true historical account of organizational culture thought going all the way back to the Hawthorne studies. It also highlights the research methods in this important area and calls for attention to historical rigor.Originality/valueThis paper fulfills the need to compare and contrast organizational culture paradigms and formally critique the current research methodology in the organizational culture field.
A dual‐band voltage‐controlled oscillator in 0.13 μm CMOS technology
Authors: Maisurah Mohd Hassan Siti , Azmi Ismail Mohd , Emran Farid Nazif , Fadhil Idham Muhammad Norman , Ismat Abdul Rahim Ahmad 
Published: July 2012

PurposeThe purpose of this paper is to design and implement a fully integrated low‐phase noise and large tuning range dual‐band LC voltage‐controlled oscillator (VCO) in 0.13 μm complementary metal oxide semiconductor (CMOS) technology.Design/methodology/approachTwo parallel‐connected single‐band VCOs are designed to implement the proposed VCO. Adopting a simple and straight‐forward architecture, the dual‐band VCO is configured to operate at two frequency bands, which are from 1.48 GHz to 1.78 GHz and from 2.08 GHz to 2.45 GHz. A band selection circuit is designed to perform band selection process based on the controlling input signal.FindingsThe proposed VCO features phase noise of −104.7 dBc/Hz and −108.8 dBc/Hz at 1 MHz offset frequency for both low corner and high corner end of the low‐band operation. For high‐band operation, phase‐noise performance of −101.1 dBc/Hz and −110.4 dBc/Hz at 1 MHz offset frequency are achieved. The measured output power of the dual‐band VCO ranges from −8.4 dBm to −5.8 dBm and from −9.6 dBm to −8.0 dBm for low‐band and high‐band operation, respectively. It was also observed that the power differences between the fundamental spectrum and the nearby spurious tone range from −67.5 dBc to −47.7 dBc.Originality/valueThe paper is useful to both the academic and industrial fields since it promotes the concept of multi‐band or multi‐standard system which is currently in demand in the telecommunication industry.
Integrating research‐based and practice‐based knowledge through workplace reflection
Authors: Nilsen Per , Nordström Gunilla , Ellström Per‐Erik 
Published: July 2012

PurposeThis paper seeks to present a theoretical framework with the aim of contributing to improved understanding of how reflection can provide a mechanism to integrate research‐based knowledge with the pre‐existing practice‐based knowledge.Design/methodology/approachThe paper begins with an explanation of important concepts: research‐based and practice‐based knowledge, four levels of action and two modes of learning. Two mini cases concerning managers in the public sector in Sweden then provide an illustration of how research‐based knowledge can be utilized to challenge practice‐based knowledge. The concluding discussion addresses some of the challenges involved in achieving reflection in the workplace that utilizes research‐based knowledge.FindingsThe reflection programmes had several characteristics that facilitated their implementation: they achieved a balance between the workplace demands on the participating managers and time required for the reflection; the participants were specifically recruited, had full management support and were highly motivated to be part of the reflection groups; the facilitators played key roles in structuring the managers' discussions and linking their experiences to relevant research‐based knowledge.Research limitations/implicationsMethodological limitations of the cases constrain the conclusions to be drawn from these studies. However, it should be emphasized that the case studies were intended primarily as illustrations of how workplace reflection can be used to integrate research‐based and practice‐based knowledge. Obviously, there is a risk of social desirability bias because the interviewer was also involved in developing and implementing the reflection programmes. She also participated as a supervisor in mini case 2.Originality/valueThe literature on reflection has largely focused on reflection in the context of education, training and preparing for work or a profession. The role of workplace reflection and learning for practitioners and managers in work has received far less attention. The emergence of the evidence‐based practice (EBP) agenda has further highlighted the importance of workplace learning and reflection, as practitioners are increasingly expected to critically appraise research studies and integrate new findings into their practice. A more EBP requires reflecting practitioners who are able to synthesize research‐based knowledge with their own practice‐based knowledge acquired through experience. However, the process of integrating research‐based and practice‐based knowledge has not been the focus of much study.
Perceived guarantees, investor protection and bailout
Authors: Trutwein Patrick , Schiereck Dirk , Thomas Matthias 
Published: July 2012

PurposeThis paper investigates the link between equity and credit markets for the government‐sponsored mortgage institutions, Fannie Mae and Freddie Mac, during the period from January 2007 until December 2008. Before the financial crisis, investors perceived these real estate finance institutions as quasi state guaranteed.Design/methodology/approachBy examining Fannie Mae and Freddie Mac during 2007 and 2008, this study extends existing research on the link between equity and credit markets. The authors employ univariate time series regression and vector autoregressive models to analyze the comovements over time and the lead‐lag relationship for equity returns, CDS spread changes, and bond spread changes.FindingsThe results provide evidence for equity returns and credit spreads of CDS and bonds being inversely related and adjusting simultaneously. The relationship between equity and credit markets intensifies during periods of heightened risks. The link between equity returns and bond spread changes is more robust in an environment of slightly elevated risk, while the relationship between equity and CDS markets intensifies during times of extreme stress. It was also found that the link between equity and credit markets completely breaks down as government intervention in the form of regulatory changes and ultimately, conservatorship, materializes.Practical implicationsInvestors active in equity and credit markets need to be aware of the relevance of the prevailing capital market regime and the role of external effects such as government support and bailout.Originality/valueThere is a growing body of empirical research employing event studies and regression analyses on the firm level to examine the link between equity and credit default swaps. Yet, to the authors' knowledge this relationship has not been explored specifically for quasi guaranteed institutions. However, given the growing number of at least partly state owned real estate finance institutions, this specific focus is important to understand future expected risk compensation of equity and credit investors. The paper ask what lessons are to be learnt from the current financial crisis about investor protection in quasi guaranteed financial institutions.
Measuring the perceived importance of ethics and social responsibility in financial services: a narrative‐inductive approach
Authors: Obalola Musa , Adelopo Ismail 
Published: July 2012

PurposeThis paper aims to reflect the argument that the impetus to engage in socially responsible actions is ultimately reinforced by the perceived belief that doing so will be beneficial to the corporation in the long run.Design/methodology/approachThe paper uses a narrative‐inductive approach to make important contributions to the corporate social responsibility‐organizational effectiveness literature. Data were collected through a semi‐structured interview, and analyzed using qualitative analysis strategies.FindingsThe study reports a profound perceived usefulness of ethics and social responsibility for business in the insurance industry in Nigeria. Furthermore, the study presents evidence that indicates that consciousness about the role of ethics and social responsibility in organizational effectiveness in this context is low, but, nevertheless suggests a positive posture towards the constructs. This positive posture seems to have been driven by the negative image of the industry and the need to remedy the situation. It suggests that this can be achieved through a show of genuine concern for the needs of the consumers, and the need to reinforce their trust and confidence in insurance as a loss mitigating mechanism.Practical implicationsWhile shareholders' value maximization was shown as one of the considerations for ethical and social responsible behavior compromise, findings from the study also suggest that stakeholders' value maximization would be an effective consideration for the industry to improve the present low market penetration. The paper draws out the need to amend short‐term goals for long‐term goals by sacrificing short‐term profits for long‐term profits and survival.Originality/valueAlthough the strategic importance of ethics and social responsibility has been investigated using the deductive approach in other industries, this work provides an alternative to this existing bulk of positivist investigations by using an inductive approach with subjects drawn from the insurance industry. The study also seems to the authors' knowledge, the first to investigate the strategic importance of this construct in a developing and apathetic market such as Nigeria.
Leak Localization in Pipelines via Computational Pipeline
Monitoring
Authors: Moustafa Kamal A. F. , Haik Yousef , Aldajah Saud , Omar Farag 
Published: July 2012

Abstract
Leaks in pipelines are unintentional releases of quantities of products from pipelines into the environment. Leaks contribute to the environmental pollution, promote corrosion and equipment failures, and produce instabilities in the pipeline operation and control. Pipeline leaks are commonly associated with third party damage, corrosion, equipment failures, and errors in pipeline design and operation. Being able to accurately detect the location of leaks is imperative. One objective of this paper is to develop a mathematical model that accounts for the behavior of pressure and flow-rate profiles in leaky pipeline systems. Such a mathematical model is needed to better understand the dynamic behavior of the pipeline and its characteristics and for the detection the leaks. The paper also involves computer simulation of pipeline conditions using the developed mathematical model and Kalman filtering technique. Leak localization is accomplished by scanning the pipeline from the inlet node to the outlet one to find the node at which the minimum residuals are obtained. Simulation results are reported to demonstrate the effectiveness of the proposed leak localization scheme.
Improving IMRT‐plan quality with MLC leaf position refinement post plan optimization
Authors: Niu Ying , Zhang Guowei , Berman Barry L. , Parke William C. , Yi Byongyong , Yu Cedric X. 
Published: July 2012

Purpose:In intensity‐modulated radiation therapy (IMRT) planning, reducing the pencil‐beam size may lead to a significant improvement in dose conformity, but also increase the time needed for the dose calculation and plan optimization. The authors develop and evaluate a postoptimization refinement (POpR) method, which makes fine adjustments to the multileaf collimator (MLC) leaf positions after plan optimization, enhancing the spatial precision and improving the plan quality without a significant impact on the computational burden.Methods:The authors’ POpR method is implemented using a commercial treatment planning system based on direct aperture optimization. After an IMRT plan is optimized using pencil beams with regular pencil‐beam step size, a greedy search is conducted by looping through all of the involved MLC leaves to see if moving the MLC leaf in or out by half of a pencil‐beam step size will improve the objective function value. The half‐sized pencil beams, which are used for updating dose distribution in the greedy search, are derived from the existing full‐sized pencil beams without need for further pencil‐beam dose calculations. A benchmark phantom case and a head‐and‐neck (HN) case are studied for testing the authors’ POpR method.Results:Using a benchmark phantom and a HN case, the authors have verified that their POpR method can be an efficient technique in the IMRT planning process. Effectiveness of POpR is confirmed by noting significant improvements in objective function values. Dosimetric benefits of POpR are comparable to those of using a finer pencil‐beam size from the optimization start, but with far less computation and time.Conclusions:The POpR is a feasible and practical method to significantly improve IMRT‐plan quality without compromising the planning efficiency.
Heavy Metal and Disinfectant Resistance of Listeria monocytogenes from Foods and Food Processing Plants
Authors: Ratani Shakir S. , Siletzky Robin M. , Dutta Vikrant , Yildirim Suleyman , Osborne Jason A. , Lin Wen , Hitchins Anthony D. , Ward Todd J. , Kathariou Sophia 
Published: July 2012

ABSTRACT

The persistence of
Listeria monocytogenes
in food processing plants and other ecosystems reflects its ability to adapt to numerous stresses. In this study, we investigated 138 isolates from foods and food processing plants for resistance to the quaternary ammonium disinfectant benzalkonium chloride (BC) and to heavy metals (cadmium and arsenic). We also determined the prevalence of distinct cadmium resistance determinants (
cadA1
,
cadA2
, and
cadA3
) among cadmium-resistant isolates. Most BC-resistant isolates were resistant to cadmium as well. Arsenic resistance was encountered primarily in serotype 4b and was an attribute of most isolates of the serotype 4b epidemic clonal group ECIa. Prevalence of the known cadmium resistance determinants was serotype associated:
cadA1
was more common in isolates of serotypes 1/2a and 1/2b than 4b, while
cadA2
was more common in those of serotype 4b. A subset (15/77 [19%]) of the cadmium-resistant isolates lacked the known cadmium resistance determinants. Most of these isolates were of serotype 4b and were also resistant to arsenic, suggesting novel determinants that may confer resistance to both cadmium and arsenic in these serotype 4b strains. The findings may reflect previously unrecognized components of the ecological history of different serotypes and clonal groups of
L. monocytogenes
, including exposures to heavy metals and disinfectants.
Genome Sequence of Klebsiella pneumoniae LZ, a Potential Platform Strain for 1,3-Propanediol Production
Authors: Tao Fei , Tai Cui , Liu Zhen , Wang Ailong , Wang Yu , Li Lixiang , Gao Chao , Ma Cuiqing , Xu Ping 
Published: July 2012

ABSTRACT

Klebsiella pneumoniae
LZ is a bacterium isolated from soil which can produce 1,3-propanediol from glycerol. Here we present a 5,431,750-bp assembly of its genome sequence. We annotated 9 coding sequences (CDSs) responsible for glycerol fermentation to 1,3-propanediol, 19 CDSs encoding glycerol utilization, and 134 CDSs related to its virulence and defense.
Genome Sequence of the Filamentous Bacterium Fibrisoma limi BUZ 3
T
Authors: Filippini Manuela , Qi Weihong , Jaenicke Sebastian , Goesmann Alexander , Smits Theo H. M. , Bagheri Homayoun C. 
Published: July 2012

ABSTRACT

Fibrisoma limi
strain BUZ 3
T
, a Gram-negative bacterium, was isolated from coastal mud from the North Sea (Fedderwardersiel, Germany) and characterized using a polyphasic approach in 2011. The genome consists of a chromosome of about 7.5 Mb and three plasmids.