bluuebunny/crossref_metadata_2025_split huggingface dataset:
Additive-based concrete evaluation using categorical boosting method
Authors: Bai Hao , Wang Wubin , Tang Hao , Li Xin , Zhao Yinting , Lv Dongqin 
Published: May 2024

This study utilized several coupled approaches to create powerful algorithms for forecasting the compressive strength (Cs) of concretes that include metakaolin (MK) and fly ash (FA). For this purpose, three various methods were considered, named random forests (RF), Categorical boosting model (CB), and extreme gradient boosting (XGB) by considering the seven most influential input variables. It was tried to divide the concrete components to binder value (B) to achieve the non-dimensional input variables. Herein, the cutting-edge Tasmanian devil Optimization (TDO) algorithm was linked with RF, XGB, and CB for the purpose of determining the optimal values of hyperparameters (named TD - CB, TD - RF, and TD - XG). It is worth mentioning that developing the mentioned algorithms optimized with TD to estimate the mechanical properties of the concrete containing several important admixtures can be recognized as this study’s contribution to practical applications. The findings indicate that the algorithms possess a notable capacity to precisely forecast the Cs of concrete, which includes MK and FA, with R2 bigger than roughly 0.97. The lower value of OBJ comprehensive index belonged to the TD - CB at 1.5762, followed by TD - XG at 1.9943 and then 2.3317 related to TD - RF with almost 70% reduction. The sensitivity analysis demonstrated that the prediction of Cs is highly influenced by all input parameters, which are higher than 0.8659, but a higher influence from MK/B at 0.9548.
Quantifying the effect of X-ray scattering for data generation in real-time defect detection
Authors: Andriiashen Vladyslav , van Liere Robert , van Leeuwen Tristan , Batenburg Kees Joost 
Published: May 2024

BACKGROUND: X-ray imaging is widely used for the non-destructive detection of defects in industrial products on a conveyor belt. In-line detection requires highly accurate, robust, and fast algorithms. Deep Convolutional Neural Networks (DCNNs) satisfy these requirements when a large amount of labeled data is available. To overcome the challenge of collecting these data, different methods of X-ray image generation are considered. OBJECTIVE: Depending on the desired degree of similarity to real data, different physical effects should either be simulated or can be ignored. X-ray scattering is known to be computationally expensive to simulate, and this effect can greatly affect the accuracy of a generated X-ray image. We aim to quantitatively evaluate the effect of scattering on defect detection. METHODS: Monte-Carlo simulation is used to generate X-ray scattering distribution. DCNNs are trained on the data with and without scattering and applied to the same test datasets. Probability of Detection (POD) curves are computed to compare their performance, characterized by the size of the smallest detectable defect. RESULTS: We apply the methodology to a model problem of defect detection in cylinders. When trained on data without scattering, DCNNs reliably detect defects larger than 1.3 mm, and using data with scattering improves performance by less than 5%. If the analysis is performed on the cases with large scattering-to-primary ratio (1 < SPR < 5), the difference in performance could reach 15% (approx. 0.4 mm). CONCLUSION: Excluding the scattering signal from the training data has the largest effect on the smallest detectable defects, and the difference decreases for larger defects. The scattering-to-primary ratio has a significant effect on detection performance and the required accuracy of data generation.
Biochemical and hematological characteristics of blood indicators, productivi-ty of piglets under the influence of additional feed “Activo”
Authors: Prudyus T. Ya. 
Published: May 2024

The article discusses the issue of the condition of the piglets' bodies before and after weaning after feeding the additional feed “Activo.” The object of the study was piglets born from sows of the large white breed of ADN genetics. Piglets were divided into control (n = 111) and experimental (n = 110). From the 5th to the 43rd day of life, the piglets were given pre-starter compound feed in loose form. In the research group's pre-starter compound feed, “Activo,” was introduced in the amount of 0.2 kg/t of finished compound feed. Blood was collected from the cranial vena cava of the piglets of the control and experimental groups for biochemical and hematological parameters on the 28th and 43rd days of the piglets' life. Productivity control was carried out by weighing animals on the day of birth, at weaning, and on the 43rd day of life. Feed consumption was monitored, and average daily gains and feed conversion were determined. According to the results of the research on piglets before weaning, we can see an increase in the total protein level in the experimental group's blood by 2.85 % compared to the control group. The albumin concentration in the control group's piglets was 47.33 %, and the experimental group was 48.00 %, which is 1.42 % more than the control group. There was also an increase in α-, β-, and γ-globulins in the experimental group. After piglets were weaned, a probable increase in total protein and albumin was noted in the experimental group by 3.96 % and 1.85 %, respectively, in the control group. At the beginning of the experiment, the piglets of the control and experimental groups had a slight difference in live weight, which was 3.35 % in favor of the control group. Already on the 28th day of life, the piglets of the research group had a live weight statistically higher by 6.58 % (P < 0.001) concerning the control. Thus, for 14 days of the experiment after weaning, the increase in live weight of piglets of the experimental group probably increased by 11.9 % (Р < 0.01), and the difference in the weight of piglets between the control and experimental groups was 0.88 kg, or 8.15 % (P < 0.001). The average daily growth rate of piglets in the experimental group also increased by 11.8 % (Р < 0.01). The difference in feed conversion between the control and experimental groups is 0.19 kg or 10.8 %.
Comparative analysis of the chemical quality of fishmeal produced on the Northwest coast of Mexico
Authors: Lizárraga-Hernández Francisco Draco , Soberanes-Yepiz Maritza L. , CORTES JACINTO Edilmar , Rangel-Dávalos Carlos , Cienfuegos-Martínez Kathia 
Published: May 2024

Objective: To evaluate the physico-chemical quality of fishmeal produced by four companies in different states of the Republic (Baja California Sur, Jalisco and Sinaloa).
Design/methodology/approach: The analyzed fishmeals were from six batches, sardine meal from California pilchard and Pacific thread herring (S. sagax and O. libertate), and skipjack tuna and (K. pelamis) processed by different Mexican companies. Proximal chemical analysis was carried out at the Centro de Investigaciones Biológicas del Noroeste (CIBNOR).
Results: The fishmeal’s quality parameters analyzed in this study showed similar values to those reported in the literature. The variations observed in their proximate chemical composition allow them to be classified according to the results of the analyses.
Limitations on study/implications: Considering that four of the six flours were produced from the same raw material, S. sagax, the high variability in their physico-chemical quality parameters indicates a lack of standardization in both production methods and quality controls among the producing companies.
Findings/conclusions: K. pelamis by-products can produce meals of equal or better physico-chemical quality than those produced from S. sagax. The development of official regulations establishing quality standards to fishmeal production at national level is desirable for competitiveness.
Investigation of Azole Resistance Involving cyp51A and cyp51B Genes in Clinical Aspergillus flavus Isolates
Authors: Ghorbel Dhoha , Amouri Imen , Khemekhem Nahed , Neji Sourour , Trabelsi Houaida , Elloumi Moez , Sellami Hayet , Makni Fattouma , Ayadi Ali , Hadrich Ines 
Published: May 2024

Abstract
This study aimed to investigate azole resistance mechanisms in Aspergillus flavus, which involve cyp51A and cyp51B genes. Real-time Reverse Transcriptase qPCR method was applied to determine the overexpression of cyp51A and cyp51B genes for 34 A. flavus isolates. PCR sequencing of these two genes was used to detect the presence of gene mutations. Susceptibility test found sensitivity to voriconazole (VOR) in all strains. 14.7% and 8.8% of isolates were resistant to itraconazole (IT) and posaconazole (POS), respectively, with a cross-resistance in 5.8%. For the double resistant isolates (IT/POS), the expression of cyp51A was up to 17-fold higher. PCR sequencing showed the presence of 2 mutations in cyp51A: a synonymous point mutation (P61P) in eight isolates, which did not affect the structure of CYP51A protein, and another non synonymous mutation (G206L) for only the TN-33 strain (cross IT/POS resistance) causing an amino acid change in the protein sequence. However, we noted in cyp51B the presence of the only non-synonymous mutation (L177G) causing a change in amino acids in the protein sequence for the TN-31 strain, which exhibits IT/POS cross-resistance. A short single intron of 67 bp was identified in the cyp51A gene, whereas three short introns of 54, 53, and 160 bp were identified in the cyp51B gene. According to the models provided by PatchDock software, the presence of non-synonymous mutations did not affect the interaction of CYP51A and CYP51B proteins with antifungals. In our study, the overexpression of the cyp51A and cyp51B genes is the primary mechanism responsible for resistance in A. flavus collection. Nevertheless, other resistance mechanisms can be involved.
KONFLIK PADA DESA ADAT DI BALI : MASALAH DAN SOLUSI PENYELESAIANNYA
Authors: Bontot I Nyoman 
Published: May 2024

Keberadaan desa adat di Bali memiliki tujuan sebagai wadah bagi warganya (krama) untuk mencapai kesejahteraan dan kebahagian (jagadhita). Untuk mencapai tujuan tersebut, setiap krama desa mendapatkan hak dan kewajiban yang diatur dalam awig-awig dan perarem sebagai aturan turunan. Berdasarkan peran dan fungsi tersebut seharusnya kehidupan masyarakat desa adat di Bali harmonis dan nirkonflik. Namun, pada kenyataannya sering terjadi konflik, seolah tidak pernah tuntas. Tujuan dari penelitian ini adalah untuk mengkaji peran dan fungsi desa adat, penyebab terjadinya konflik, dan solusi untuk meredakan konflik yang dialami desa adat di Bali. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan etnografi. Menggunakan data sekunder dikumpulkan dari beberapa hasil penelitian terdahulu. Permasalahan dianalisis menggunakan Teori Struktural Fungsional dan Teori Konflik Sosial. Hasil penelitian ini menyimpulkan bahwa desa ada memiliki peran dan fungsi sebagai wadah warganya untuk mencapai tujuan, yaitu jagadhita, konflik yang terjadi di desa adat adalah konflik sosial yang disebabkan oleh ketidakpatuhan warga terhadap awig-awig dan kuasa para elit yang tidak adil, dan konflik pada desa adat perlu diselesaikan dengan multi pendekatan.
Arak Bali Dalam Kehidupan Masyarakat Karangasem Bali Perspektif Sosioreligius
Authors: Putra I Wayan Sunampan 
Published: May 2024

Arak Bali merupakan salah satu kebudayaan Bali yang di dalamnya terdapat kebudayaan universal. Baik halnya sistem kepercayaan, sistem sosial, sistem pengetahuan, teknologi, sistem ekonomi, bahasa dan kesenian. Namun dalam perkembangannya, arak Bali memperlihatkan adanya kontradiksi. Kontradiksi yang terlihat yakni memiliki dua sisi yang bertentangan baik yang bersifat positif maupun negatif sebagai sistem kebudayaan. Namun dibalik kontradiksinya, arak Bali tetap eksis dalam kehidupan masyarakat Bali. Adapun alasan mengapa arak Bali masih bisa eksis yakni karena adanya faktor teologis, faktor sosiologis dan faktor ekonomi. Penggunaan arak Bali dalam masyarakat biasanya digunakan sebagai pendukung aktivitas reitual. Digunakan sebagai perekat hubungan solidaritas. Dari penggunaannya, maka arak Bali tentu berimplikasi terhadapa kebudayaan Bali, yakni implikasi dalam aspek teologis. Implikasi terhadap hubungan sosial, dan implikasi terhadap perekonomian masyarakat.
Analysis Of Yanbu'a Method In Improving Reading and Writing Arabic Pegon
Authors: Nailah Nailah haflah , Anita Anita pujiastutik , Budi Budi hariyanto 
Published: May 2024

Pendidikan memiliki pengaruh yang tidak terbatas. Sehingga jika ingin pendidikan itu dapat berjalan dengan baik, maka komponen-komponenyanya harus terpenuhi terlebih dahulu. Adapun komponen tersebut adalah adanya pendidik, peserta didik, tujuan, materi, metode, alat/media dan lingkungan/tempat. Komponen pendidikan yang baik akan mampu menciptakan generasi-generasi yang baik pula. Dalam mendidik seorang anak tidak hanya dengan pembelajaran formal saja, namun juga dilengkapi dengan pengetahuan agama. Harapan tertinggi dalam sebuah keluarga saat ini adalah tercetaknya generasi Qur’ani yang sholeh dan sholehah, yang berguna bagi nusa, bangsa dan agamanya, sehingga diperlukannya pendidikan Al Qur’an yang baik dan tidak sembarangan. Saat ini ada banyak sekali variasi metode pembelajaran Al Qur’an, namun tidak banyak yang mempengaruhi minat anak dalam mengkaji Al Qur’an. Penelitian ini dilakukan penedekatan kualitatif dengan pendekata deskriptif, yakni penelitian yang menghasilkan data deskriptif berupa kata atau lisan, sehingga data yang didapat lebih akurat. Dari hasil penelitian ini penulis dapat simpulkan bahwa metode pengkajian Yanbu’a merupakan metode yang efektif untuk diterapkan di TPA Nurul Huda Krian karena dalam metode ini tidak hanya diajarkan cara membaca dan menulis Al Qur’an saja, namun peserta didik juga bisa mempelajari baca tulis arab pegon yang merupakan pedoman untuk membaca kitab-kitab salaf dan bekal utama untuk melanjutkan pendidikan agama di pondok pesantren maupun madrasah diniyah.
Analisis Retribusi Pasar Terhadap Peningkatan Pendapatan Pedagang Pasar Tradisional Narang
Authors: Nagut Stefanus , Setyabudi Deni Nugroho , Rakhmadian Miftah 
Published: May 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh retribusi pasar terhadap peningkatan pendapatan pedagang pasar tradisional Narang, serta untuk mengetahui apa yang menjadi faktor pendorong dan penghambat dari pengaruh retribusi pasar guna meningkatkan pendapatan pedagang pasar tradisional Narang. Sedangkan metode penelitian yang digunakan adalah metode kualitatif yaitu dengan menemukan, memahami, menjelaskan dan memperoleh gambaran tentang upaya pemerintah daerah dalam meningkatkan pendapatan retribusi pasar serta mengumpulkan fakta-fakta mengenai pengaruh retribusi pasar terhadap peningkatan pendapatan pedagang pasar. Hasil penelitian menunjukkan: bahwa aspek retribusi pasar memberikan pengaruh yang besar terhadap peningkatan pedapatan pedagang melalui penataan dan pengelolaan pasar Narang yang lebih baik.
Implementasi Pembelajaran Dengan Menggunakan Literasi Digital Sebagai Sarana Meningkatkan Prestasi Belajar Siswa di SMP Islam Klojen Lumajang
Authors: Likasari Gati Ayu , Kholidah Dina 
Published: May 2024

Pembelajaran pada hakikatnya tidak hanya sekedar menyampaikan pesan tetapi juga merupakan aktifitas profesional yang menuntut guru dapat menggunakan keterampilan dasar mengajar secara terpadu serta menciptakan situasi efisien. Pembelajaran literasi digital dengan memanfaatkan alat komunikasi yang diterapkan di SMP Islam Klojen Lumajang diharapkan mampu meningkatkan prestasi belajar siswa. Prestasi belajar yang didapatkan oleh siswa menjadi hal yang perlu diperhatikan agar guru dapat melihat sejauh mana pemahaman siswa saat pembelajaran dengan menggunakan literasi digital. Penelitian ini bertujuan untuk mengetahui penerapan pembelajaran literasi digital yang digunakan SMP Islam Klojen Lumajang dalam pembelajaran IPS, untuk mengetahui penerapan pembelajaran literasi digital dalam kaitannya dengan prestasi belajar siswa, untuk mengetahui strategi yang digunakan agar pembelajaran literasi digital dapat terus dilaksanakan dan berkembang dalam meningkatkan prestasi belajar siswa pada mata pelajaran IPS. Jenis penelitian ini menggunakan kualitatif naratif. Pengumpulan data dilakukan dengan metode observasi, wawancara dan dokumentasi. Keabsahan data digunakan teknik ketekunan di lapangan dan triangulasi sumber. Analisis data dalam penelitian ini pengecekan, pengelompokan dan penarikan kesimpulan. Jumlah informan dalam penelitian ini adalah 10 orang. Berdasarkan hasil penelitian, dapat diketahui bahwa pembelajaran literasi digital di SMP Islam Klojen Lumajang sudah berjalan dengan baik, dengan memanfaatkan alat komunikasi (handphone) sebagai penunjang kegiatan pembelajaran. Pembelajaran literasi digital efektif diterapkan untuk meningkatkan prestasi belajar siswa. Hal tersebut dapat dilihat dari peningkatan prestasi belajar yang didapatkan oleh siswa yang mengalami kenaikan dari batas nilai KKM. Siswa juga memiliki minat yang tinggi pada saat belajar dengan menggunakan pembelajaran literasi digital membuat siswa lebih memahami materi IPS yang di ajarkan.
Pengaruh Promosi dan Harga Terhadap Keputusan Pembelian Produk Kosmetik Wardah Pada Mahasiswi Fakultas Humaniora Universitas Sari Mulia
Authors: Normilawati Normilawati , Kusumawati Linda , Rezeki Yuliarti 
Published: May 2024

Penampilan adalah hal yang penting, terutama perempuan. Penggunaan kosmetik tidak hanya ketika akan pergi ke acara formal, banyak perempuan terutama kalangan mahasiswi menggunakan kosmetik terlebih sekedar memakai liptint untuk pergi ke kampus. Konsumen biasanya memilih produk yang memiliki kualitas baik, harga terjangkau dan sudah diperiksa oleh Badan Pengawas Obat Dan Makanan (BPOM). Berdasarkan hasil observasi yang dilakukan terhadap mahasiswi Fakultas Humaniora Universitas Sari Mulia, ditemukan sebagian besar menyatakan menggunakan produk kosmetik Wardah. Berdasarkan latar belakang masalah dan teori yang dikemukan peneliti tertarik untuk meneliti terkait “Pengaruh Promosi Dan Harga Terhadap Keputusan Pembelian Produk Kosmetik Wardah Pada Mahasiswi Fakultas Humaniora Universitas Sari Mulia”. Tujuan penelitian ini untuk mengetahui pengaruh variabel promosi dan harga secara parsial dan simultan terhadap keputusan pembelian produk kosmetik Wardah. Penelitian ini menggunakan metode penelitian kuantitatif dengan kousioner yang dibagikan ke Mahasisiwi Fakultas Humaniora Universitas Sari Mulia. Dari hasil pengujian statistik secara parsial dinyatakan bahwa Promosi tidak berpengaruh signifikan secara parsial, sedangkan Harga berpengaruh signifikan. Promosi dan Harga berpengaruh signifikan secara simultan terhadap Keputusan Pembelian. Jadi dapat disimpulkan Promosi tidak berpengaruh secara parsial, sedangkan harga berpengaruh secara parsial terhadap keputusan pembelian. Promosi dan harga berpengaruh secara simultan terhadap keputusan pembelian.
Association of urinary bisphenol A levels with heart failure risk in U.S. adults from the NHANES (2003–2016)
Authors: Ma Yuanyuan , Huang Haobin , Qian Haiyun , Wu Yanhu , Gao Zhe 
Published: May 2024

IntroductionAlthough heart failure (HF) has been linked to bisphenol A (BPA), few studies have investigated the cut-off values for the effects of urinary BPA levels on heart failure risk. The association between urinary BPA levels and HF prognosis has not been investigated.MethodsThis study included 11,849 adults over 20 years old using information from the National Health and Nutrition Examination Survey (NHANES), which was conducted from 2003 to 2016. The relationship between urinary BPA levels and the risk of HF was determined via a multivariable logistic regression model, and restricted cubic spline (RCS) methods were used to determine the cut-off for the effect of BPA levels on HF risk. Based on the available NT-proBNP concentration data from the NHANES (2003–2004), multivariable linear regression was applied to determine the linear association between the NT-proBNP concentration and urinary BPA concentration.ResultsThe results revealed a positive correlation between a urinary BPA concentration in the fourth quartile and the occurrence of heart failure [OR 1.49, 95% CI (1.09, 2.04), p = 0.012]. A one-unit increase (1 ng/mg creatinine) in the ln-transformed BPA concentration was linked to a 15% increase in the incidence of HF [OR 1.15, 95% CI (1.03, 1.29), p = 0.014]. The cut-off urinary BPA concentration for HF risk was 1.51 ng/mg creatinine. There was a positive correlation between urinary BPA and NT-proBNP concentrations [β = 0.093, 95% CI (0.014, 0.171), p = 0.02] in males, but there was no linear association [β = 0.040, 95% CI (−0.033, 0.113), p = 0.283] in females.DiscussionIncreased urinary BPA levels are linked to an increased risk of heart failure and poor prognosis. There is a significant increase in the risk of heart failure if the urinary concentration of BPA exceeds 1.51 ng/mg creatinine.
Material basis and molecular mechanisms of Chaihuang Qingyi Huoxue Granule in the treatment of acute pancreatitis based on network pharmacology and molecular docking-based strategy
Authors: Yang Jia , Jiang Yu-Hong , Zhou Xin , Yao Jia-Qi , Wang Yang-Yang , Liu Jian-Qin , Zhang Peng-Cheng , Tang Wen-Fu , Li Zhi 
Published: May 2024

ObjectivesThis study aimed to analyze active compounds and signaling pathways of CH applying network pharmacology methods, and to additionally verify the molecular mechanism of CH in treating AP.Materials and methodsNetwork pharmacology and molecular docking were firstly used to identify the active components of CH and its potential targets in the treatment of AP. The pancreaticobiliary duct was retrogradely injected with sodium taurocholate (3.5%) to create an acute pancreatitis (AP) model in rats. Histological examination, enzyme-linked immunosorbent assay, Western blot and TUNEL staining were used to determine the pathway and mechanism of action of CH in AP.ResultsNetwork pharmacological analysis identified 168 active compounds and 276 target proteins. In addition, there were 2060 targets associated with AP, and CH had 177 targets in common with AP. These shared targets, including STAT3, IL6, MYC, CDKN1A, AKT1, MAPK1, MAPK3, MAPK14, HSP90AA1, HIF1A, ESR1, TP53, FOS, and RELA, were recognized as core targets. Furthermore, we filtered out 5252 entries from the Gene Ontology(GO) and 186 signaling pathways from the Kyoto Encyclopedia of Genes and Genomes(KEGG). Enrichment and network analyses of protein-protein interactions predicted that CH significantly affected the PI3K/AKT signaling pathway, which played a critical role in programmed cell death. The core components and key targets showed strong binding activity based on molecular docking results. Subsequently, experimental validation demonstrated that CH inhibited the phosphorylation of PI3K and AKT in pancreatic tissues, promoted the apoptosis of pancreatic acinar cells, and further alleviated inflammation and histopathological damage to the pancreas in AP rats.ConclusionApoptosis of pancreatic acinar cells can be enhanced and the inflammatory response can be reduced through the modulation of the PI3K/AKT signaling pathway, resulting in the amelioration of pancreatic disease.