bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green cutworm Anicla ignicans (Lepidoptera: Noctuidae): Identity, geographical distribution, immature morphology, host plants and biology in controlled conditions
Authors: Piovesan Mônica , Orlandin Elton , Carneiro Eduardo , Venâncio Lidia , Roque‐Specht Vânia Ferreira , Casagrande Mirna Martins , Mielke Olaf Hermann Hendrik , Bonfin Felipe Alverne Dourado , Vieira Paulo Victor Machado , Specht Alexandre 
Published: May 2024

AbstractThe subgenus Anicla, commonly known as green cutworms, harbours some of the owlet moths (Lepidoptera: Noctuinae), whose larvae are notable for their economic importance. Knowledge of the immature stages for this group is available for three of the nine described species. Anicla infecta Ochsenheimer, 1816 is widely distributed in the Americas and is especially abundant in agricultural ecosystems. However, in the Neotropics, its economic damage can be confused with sympatric species, including Anicla ignicans (Guenée, 1852), whose distributions overlap in most parts of the American continent. In this sense, here, the identity of A. ignicans is investigated through its geographical distribution, based on molecular and morphological data. Additionally, the morphological and behavioural traits of immature stages were described in detail, information about its geographical distribution and larval host plants was gathered, and the species' biological parameters from larvae reared on an artificial diet were determined. Anicla ignicans is distributed throughout the Neotropical region, preferably in areas with xeric and/or grass‐dominated ecosystems. The eggs present valuable characters to distinguish A. ignicans from other owlet moth species, such as the reduced number of ribs, the way the micropyle openings are arranged and the shape of the aeropyles. However, the larvae show very similar chromatic polymorphisms to other Anicla species. Although A. ignicans prefer to feed on grasses, it was observed that more than 85% of the larvae that were fed with a modified bean‐based Greene diet survived. Additionally, the percentage of time for each phase of development obtained here is very similar for the different species of Anicla, regardless of the temperature or feeding of the larvae.
Long‐term efficacy and safety of brolucizumab in neovascular age‐related macular degeneration: A multicentre retrospective real‐world study
Authors: Kim Dong Ju , Kim Dong Geun , Kwak Hyun Duck , Jang Jae Yong , Ji Yong‐Sok , Lee Seung Hyun , Lee Eun Kyoung , Park Kyu Hyung , Kim Jae Hui , Lee Jun Sung , Song Yumi , Kim Seong Taeck , Shin Min Ho , Kim Min , Park Sang Jun , Joo Kwangsic , Sagong Min , Lee Christopher Seungkyu , Woo Se Joon 
Published: May 2024

AbstractPurposeTo investigate the long‐term efficacy and safety of intravitreal brolucizumab (BRZ) injections in patients with typical neovascular age‐related macular degeneration (typical nAMD) and polypoidal choroidal vasculopathy (PCV).MethodsThis multicentre retrospective study included 401 eyes of 398 patients with nAMD who received BRZ injection(s), with a follow‐up duration of ≥12 months. Changes in best‐corrected visual acuity (BCVA), retinal fluid evaluation and central subfield thickness (CST) on optical coherence tomography were assessed. The efficacy of BRZ was compared between typical nAMD and PCV groups.ResultsAnalyses were conducted with 280 eyes of 278 patients with typical nAMD and 121 eyes of 120 patients with PCV (mean age, 71.1 ± 8.6 years). 29 eyes (7.2%) were treatment naïve. The mean follow‐up period was 15.3 ± 2.8 months; the mean number of BRZ injections within 1 year was 4.5 ± 1.7. BCVA was maintained during the follow‐up period, and CST significantly improved from the first injection month and was maintained for 12 months in both the typical nAMD and PCV groups. The dry macula proportion increased from 2.7% at baseline to 56.1% at 1 month and 42.9% at 12 months. Among the 18 eyes that underwent indocyanine green angiography both before and after treatment, 10 (55.6%) showed polyp regression. Overall, the incidence of intraocular inflammation (IOI), retinal vasculitis and occlusive retinal vasculitis was 9.4% (38 eyes), 1.2% (5 eyes) and 0.5% (2 eyes), respectively. IOI occurred from the first to the sixth injections, with an average IOI onset of 28.5 ± 1.4 days. All eyes achieved IOI resolution, although the two eyes with occlusive retinal vasculitis showed a severe visual decline after IOI resolution.ConclusionBrolucizumab was effective in maintaining BCVA and managing fluid in eyes with nAMD for up to 1 year, exhibiting a high polyp regression rate. However, the not uncommon incidence of IOI and the severe visual decline caused by the rare occlusive retinal vasculitis following BRZ treatment underscore the importance of careful monitoring and timely management.
Editorial: Mortality in immune‐mediated inflammatory diseases during early adulthood—Authors' reply
Authors: Malham Mikkel , Jansson Sabine , Ingels Helene , Jørgensen Marianne Hørby , Rod Naja Hulvej , Wewer Vibeke , Fox Matthew P. 
Published: May 2024

LINKED CONTENTThis article is linked to Malham et al papers. To view these articles, visithttps://doi.org/10.1111/apt.17994andhttps://doi.org/10.1111/apt.18012.
Effects of slatted frame placed in compost pile on enhancing heat generation and organic matter degradation during high‐moisture cow manure composting
Authors: Hanajima Dai 
Published: May 2024

AbstractExcess moisture content in cow manure inhibits the process of composting. This study examined the effects of introducing a slatted frame on temperature development, organic matter degradation, and moisture content during high‐moisture composting. Twelve tons of cow manure was piled individually, and an iron slatted frame with a pipe and a plain frame filled inside with styrofoam was introduced in the treatment and control piles, respectively. Two hours after the start, running leachate via the pipe in the treatment pile was observed, but not in the control pile. The maximum temperatures as well as durations of the temperatures above 55°C of the treatment piles at all seven positions were higher than those of the control piles. In particular, four of the seven positions in the treatment pile exhibited more than twice the duration. Installing the slatted frame improved the organic matter degradation; the values of organic matter loss in the control and treatment were 48.0% and 58.4%, respectively. The final moisture content in the treated compost was 5% lower than that in the control. Overall, the introduction of a slatted frame generated higher temperatures and produced relatively dried and well‐degraded compost.
Therapeutic drug monitoring of osimertinib in EGFR mutant non‐small cell lung cancer by dried blood spot and plasma collection: A pilot study
Authors: Narayanan Sathya , Yuile Alexander , Venkatesh Bharat , McKay Matthew , Itchins Malinda , Pavlakis Nick , Wheeler Helen , Gray Lauren , Wei Joe , Miller Samuel , Kirwin Brendan , Molloy Mark P. , Clarke Stephen 
Published: May 2024

AimsTherapeutic drug monitoring (TDM) has led to significant improvements in individualized medical care, although its implementation in oncology has been limited to date. Tyrosine kinase inhibitors (TKIs) are a group of therapies for which TDM has been suggested. Osimertinib is one such therapy used in the treatment of epidermal growth factor receptor (EGFR) mutation‐driven lung cancer. Herein, we describe a prospective pilot study involving 21 patients on osimertinib primarily as a preliminary evaluation of drug levels in a real‐world setting.MethodsConcentrations of the drug and its primary metabolites were measured with a validated liquid chromatography–mass spectrometry (LC–MS) assay across serial timepoints. As part of this study, inter‐individual variability by dose and ethnicity as well as intra‐individual variability across timepoints are explored. Furthermore, we attempted to validate dried blood spot (DBS)‐based quantitation as an accurate alternative to plasma quantitation.ResultsSuccessful quantitation of osimertinib and primary metabolites was achieved for our subjects. Compound plasma levels were highly correlated to DBS levels. There was no significant difference in concentrations with ethnicity or dosing or intra‐individual variability across timepoints.ConclusionsAs such, we demonstrate that TDM for osimertinib is practical for future trials. We also validated the use of DBS as an alternative to conventional quantitation for exploration of TDM for osimertinib in larger trials and for other targeted therapies.
Effects of physically active maths lessons on children's maths performance and maths‐related affective factors: Multi‐arm cluster randomized controlled trial
Authors: Syväoja Heidi J. , Sneck Sirpa , Kukko Tuomas , Asunta Piritta , Räsänen Pekka , Viholainen Helena , Kulmala Janne , Hakonen Harto , Tammelin Tuija H. 
Published: May 2024

AbstractBackgroundPhysical activity (PA) may benefit academic performance, but it is unclear what kind of classroom‐based PA is optimal for learning.AimWe studied the effects of physically active maths lessons on children's maths performance and maths‐related effects, and whether gender and previous mathematical or motor skills modify these effects.SampleA total of 22 volunteered teachers and their pupils with signed consent (N = 397, mean age: 9.3 years, 51% females) participated in a 5‐month, teacher‐led, multi‐arm, cluster‐randomized controlled trial.MethodsThe intervention included a PAL group (20 min of physically active learning in each 45‐min lesson), a breaks group (two 5‐min PA breaks in each 45‐min lesson) and a control group (traditional teaching). Maths performance was assessed with a tailored curriculum‐based test. Maths‐related enjoyment, self‐perceptions and anxiety were measured with a self‐reported questionnaire. The individual‐level intervention effects were tested via covariate‐adjusted linear mixed‐effect models with school classes serving as random effects.ResultsChanges in maths performance or self‐perceptions did not differ between the intervention groups. Maths anxiety in learning situations increased in the PAL group (effect .28, 95% CI = .01–.56); there was no change in the other groups. Subgroup analyses suggested that maths anxiety increased in the PAL group among children in the two lowest tertiles of motor skills. It decreased in the highest tertile. Enjoyment decreased in the breaks group among pupils in the lowest motor skill tertile.ConclusionsPhysically active maths lessons did not affect maths performance or self‐perceptions but had divergent effects on maths anxiety and enjoyment, depending on motor skills.
Us, them and we: How national and human identifications influence adolescents' ethnic prejudice
Authors: Bobba Beatrice , Thijs Jochem , Crocetti Elisabetta 
Published: May 2024

AbstractAlthough there have been numerous studies on the relations between group identification and ethnic prejudice, it is less clear whether their associations reflect stable individual tendencies or rather situational or temporal fluctuations. This longitudinal multilevel study aimed to fill this gap by examining the between‐ and within‐person associations of identification with the national and superordinate human groups and levels of prejudice against multiple ethnic minorities. A total of 883 Italian majority adolescents (Mage = 15.66, SD = 1.15 at T1, 49.7% females) completed questionnaires at four time points over the course of 1 year. Results showed that national identification was related to more prejudice at the between‐person level but to decreases in prejudice at the within‐person level. Additionally, human identification contributed to lower levels of and steeper decreases in prejudice at both the between‐ and within‐person levels. Common and unique associations also emerged across different ethnic minority targets, but only for between‐person effects. Overall, this study highlights the importance of distinguishing stable individual levels and momentary fluctuations of both ingroup identifications and ethnic prejudice in order to orient future interventions aimed at improving the quality of intergroup relationships.
The language of light: a review of bioluminescence in deep‐sea decapod shrimps
Authors: Collins Stormie B. , Bracken‐Grissom Heather D. 
Published: May 2024

ABSTRACTIn the dark, expansive habitat of the deep sea, the production of light through bioluminescence is commonly used among a wide range of taxa. In decapod crustaceans, bioluminescence is only known in shrimps (Dendrobranchiata and Caridea) and may occur in different modes, including luminous secretions that are used to deter predators and/or from specialised light organs called photophores that function by providing camouflage against downwelling light. Photophores exhibit an extensive amount of morphological variation across decapod families: they may be internal (of hepatic origin) or embedded in surface tissues (dermal), and may possess an external lens, suggesting independent origins and multiple functions. Within Dendrobranchiata, we report bioluminescence in Sergestidae, Aristeidae, and Solenoceridae, and speculate that it may also be found in Acetidae, Luciferidae, Sicyonellidae, Benthesicymidae, and Penaeidae. Within Caridea, we report bioluminescence in Acanthephyridae, Oplophoridae, Pandalidae, and new observations for Pasiphaeidae. This comprehensive review includes historic taxonomic literature and recent studies investigating bioluminescence in all midwater and deep benthic shrimp families. Overall, we report known or suspected bioluminescence in 157 species across 12 families of decapod shrimps, increasing previous records of bioluminescent species by 65%. Mounting evidence from personal observations and the literature allow us to speculate the presence of light organs in several families thought to lack bioluminescence, making this phenomenon much more common than previously reported. We provide a detailed discussion of light organ morphology and function within each group and indicate future directions that will contribute to a better understanding of how deep‐sea decapods use the language of light.
Integrating socioeconomic and ecological data into restoration practice
Authors: Villarreal‐Rosas Jaramar , Brown Christopher J. , Andradi‐Brown Dominic A. , Domínguez Ricardo , Jacobo Pilar , Martínez Anuar , Mascote Coral , Najera Eduardo , Paiz Yves , Vázquez Moran Víctor Hugo , Villarreal Jaime , Adame María F. 
Published: May 2024

AbstractDriven by the United Nations Decade on Restoration and international funding initiatives, such as the Mangrove Breakthrough, investment in mangrove restoration is expected to increase. Yet, mangrove restoration efforts frequently fail, usually because of ad hoc site‐selection processes that do not consider mangrove ecology and the socioeconomic context. Using decision analysis, we developed an approach that accounts for socioeconomic and ecological data to identify sites with the highest likelihood of mangrove restoration success. We applied our approach in the Biosphere Reserve Marismas Nacionales Nayarit, Mexico, an area that recently received funding for implementing mangrove restoration actions. We identified 468 potential restoration sites, assessed their restorability potential based on socioeconomic and ecological metrics, and ranked sites for implementation with spatial optimization. The metrics we used included favorable conditions for propagules to establish and survive under sea‐level rise, provision of ecosystem services, and community dynamics. Sites that were selected based on socioeconomic or ecological metrics alone had lower likelihood of mangrove restoration success than sites that were selected based on integrated socioeconomic and ecological metrics. For example, selecting sites based on only socioeconomic metrics captured 16% of the maximum attainable value of functioning mangroves able to provide propagules to potential restoration sites, whereas selecting sites based on ecological and socioeconomic metrics captured 46% of functioning mangroves. Our approach was developed as part of a collaboration between nongovernmental organizations, local government, and academics under rapid delivery time lines given preexisting mangrove restoration implementation commitments. The systematic decision process we used integrated socioeconomic and ecological considerations even under short delivery deadlines, and our approach can be adapted to help mangrove restoration site‐selection decisions elsewhere.
Partisanship, optimism, and firm innovation
Authors: Jiao Anqi , Lu Juntai , Ren Honglin 
Published: May 2024

AbstractPolitical partisanship significantly shapes firm executives’ economic outlook. We find that firms, whose managers share political alignment with the US president, achieve superior innovation outcomes, including higher patent counts, increased patent citations, and greater patent value. We establish a causal relationship through a difference‐in‐differences approach, focusing on periods around US presidential elections. This effect is more pronounced in firms with overconfident CEOs and during periods of heightened policy uncertainty, suggesting that partisan optimism stimulates innovation incentives. Firms led by partisan‐aligned managers generate patents with greater originality, generality, and an exploratory style.
Unveiling crisis in globalised higher education: Artificial intelligence insights from doctoral research in EThOS
Authors: Montgomery Catherine , Stewart Craig , Aduragba Olanrewaju , Poli Francesca 
Published: May 2024

AbstractThis paper seeks to illuminate new perspectives on the concept of crisis in globalised higher education (HE) by focusing on knowledge generated by doctoral research. Doctoral research is a significant part of research and knowledge building in HE, particularly in science, and doctoral students contribute to the research capacity and knowledge building of institutions. This source of knowledge offers alternative perspectives on crisis in HE, providing a rich source of research which is often under‐consulted. Using the British Library's digital repository EThOS, a collection of around 637,000 doctoral studies carried out in British universities, the research harnesses Generative Artificial Intelligence approaches in order to analyse the ways in which crisis is defined and constructed in doctoral research since 2000. Through a pilot study using a prototype of a new AI tool, the paper offers both conceptual and methodological insights into constructions of crisis in this under‐used field of research.
Essential oil vapour inclusion in protective atmosphere packaging for shelf‐life management of fisheries
Authors: Nobile Maria , Ghidini Sergio , Panebianco Felice , Pessina Davide , Chiesa Luca Maria , Panseri Sara 
Published: May 2024

SummaryFish is well known for its perishable nature. Essential oils in food packaging seem to be safe and reliable both in terms of safety for the consumer and in terms of improving the shelf life of the product. This study aimed to evaluate the effects of two different essential oil vapours (one with rosemary and the other one with lemon extract) on three different types of fishery products (swordfish steaks, bluefin tuna steaks and Argentinian prawns) stored in a protective atmosphere packaging, monitoring the shelf life up to 8 days through microbiological, chemical and sensorial analyses. The results showed that the products preserved with the inclusion of essential oils have reached the end of the shelf‐life period respecting the process hygiene and food safety criteria, receiving a greater appreciation rating from the consumer panel at the end of shelf life for the prawns and swordfish samples with the addition of rosemary essential oils vapours, which instead highlighted the worst result at the end of shelf life for tuna.
The impact of passion fruit peel powder on the physicochemical, sensory properties, and antioxidant activity of goat milk yoghurt
Authors: Liu Zhaohan , Yang Tongxiang , Chen Junliang , Yang Chenze , Niu Junqiang , Duan Xu , Ren Guangyue , Li Linlin 
Published: May 2024

SummaryThere is significant economic potential in reusing passion fruit peel as an industrial by‐product, and there has been enthusiasm for creating new goat milk yoghurt (GMY) products. Consequently, a thorough investigation regarding the impact of passion fruit peel on fermented GMY is crucial for the advancement of new food products. This study aimed to assess the impact of passion fruit peel powder (PFPP) on the quality characteristics, sensory properties, and antioxidant activity of GMY during storage. Six GMY formulations were prepared by varying the amount of PFPP addition (0%, 0.5%, 1.0%, 1.5%, 2.0%, and 2.5%). The results revealed that several characteristics of GMY were positively affected by the addition of PFPP, including the acidity, rheology, and texture property of the samples. It was observed that GMY with 1.0% addition of PFPP exhibited improved taste, flavour, and colour. Additionally, the total phenols, flavonoids, anthocyanin, and antioxidant properties of GMY with PFPP were significantly increased across all levels. The results obtained from this study demonstrate that PFPP has the potential to be utilised in GMY to optimise the benefits of products with high antioxidant activity.
Genetic polymorphisms of TLR1, TLR2, TLR3 and TLR4 in patients with recurrent or severe infections
Authors: Teräsjärvi Johanna , Kainulainen Leena , Peltola Ville , Mertsola Jussi , Hakanen Antti , He Qiushui 
Published: May 2024

AbstractToll‐like receptors (TLRs) play an important role in innate immunity. Previous studies have shown that single nucleotide polymorphisms (SNPs) in the genes coding for these innate immune molecules can affect susceptibility to and the outcome of certain diseases. The aim of the present study was to examine the clinical relevance of well‐studied TLR1–4 SNPs in individuals who are prone to infections. Four functional SNPs, TLR1 rs5743618 (1805C > A, Ser602Ile), TLR2 rs5743708 (2258G > A, Arg753Gln), TLR3 rs3775291 (1234C > T, Leu412Phe) and TLR4 rs4986790 (896A > G, Asp299Gly), were analysed in 155 patients with recurrent respiratory infections (n = 84), severe infections (n = 15) or common variable immunodeficiency (n = 56), and in 262 healthy controls, using the High Resolution Melting Analysis method. Polymorphisms of TLR2 rs5743708 (odds ratio [OR] 3.16; 95% confidence interval [CI] 1.45–6.83, p = .004, ap = .016) and TLR4 rs4986790 (OR 1.8; 95% CI 1.05–3.12, p = .028, ap = .112) were more frequent in patients with recurrent or severe infections than in controls. Interestingly, seven patients were found to carry both variant genotypes of TLR2 and TLR4, whereas none of the control group carried such genotypes (p ≤ .0001). Moreover, TLR2 polymorphism was associated with increased risk for acute otitis media episodes (OR, 3.02; 95% CI 1.41–6.47; p = .012). This study indicates that children and adults who are more prone to recurrent or severe respiratory infections carry one or both variant types of TLR2 and TLR4 more often than control subjects. Genetic variations of TLRs help explain why some children are more susceptible to respiratory infections.
The Decline and Retrieval of Divine Incomprehensibility in Modern Reformed Theology
Authors: O'Grady Jack 
Published: May 2024

AbstractThis article explores the way in which two modern Reformed theologians, Charles Hodge and Herman Bavinck, articulate their theologies of divine incomprehensibility and the knowability of God in radically different ways, against the backdrop of post‐Kantian epistemology. This contrast will draw attention to why the doctrine of divine incomprehensibility has diminished in influence in modern Reformed theology, while also making some suggestions as to how it can be retrieved in order to supplement and strengthen contemporary discussions on the doctrine of God in the Reformed tradition.