bluuebunny/crossref_metadata_2025_split huggingface dataset:
Degrading effect on electrical properties of printed gallium sulfide based photodetector
Authors: Odaci Cem , Khan Muhammad Shaukat , Jose Manoj , Kisielewska Marta , Roshanghias Ali , Aydemir Umut 
Published: May 2024

Abstract
Layered GaS structures have been attracting increasing research interest due to their highly anisotropic structural, electrical, optical, and mechanical properties. However, the investigation of the performance based on the responsivity, external quantum efficiency, and detectivity of printed GaS based photodetector on a flexible PET substrate with respect to a period of time under the environmental conditions have not been reported so far. This experimental study shows that the printed GaS based photodetector stored in ambient conditions undergoes a change in terms of performance in a few weeks after the fabrication. This work also holds an importance being premier study experimentally investigating the printed III–VI group monochalcogenide based photodetector stored under the environmental conditions and contributing the literature to improve the printed device performance in further applications.
Quantum Fisher kernel for mitigating the vanishing similarity issue
Authors: Suzuki Yudai , Kawaguchi Hideaki , Yamamoto Naoki 
Published: May 2024

AbstractQuantum kernel (QK) methods exploit quantum computers to calculate QKs for the use of kernel-based learning models. Despite a potential quantum advantage of the method, the commonly used fidelity-based QK suffers from a detrimental issue, which we call the vanishing similarity issue; the exponential decay of the expectation value and the variance of the QK deteriorates implementation feasibility and trainability of the model with the increase of the number of qubits. This implies the need to design QKs alternative to the fidelity-based one. In this work, we propose a new class of QKs called the quantum Fisher kernels (QFKs) that take into account the geometric structure of the data source. We analytically and numerically demonstrate that the QFK can avoid the issue when shallow alternating layered ansatzes are used. In addition, the Fourier analysis numerically elucidates that the QFK can have the expressivity comparable to the fidelity-based QK. Moreover, we demonstrate synthetic classification tasks where QFK outperforms the fidelity-based QK in performance due to the absence of vanishing similarity. These results indicate that QFK paves the way for practical applications of quantum machine learning toward possible quantum advantages.
An element perception and state recognition method oriented to complex assembled product
Authors: Zhao Delong , Kong Feifei , Du Fuzhou 
Published: May 2024

Abstract
Quality inspection during assembly process has an important impact on the performance and service life of the final product. Automated inspection solutions based on machine vision and artificial intelligence greatly improve the efficiency of inspection. However, the current mainstream large-scene inspection solutions, such as mobile vision platforms, are difficult to apply widely due to cost issues. Therefore, portable vision inspection solutions have gradually gained attention. However, the bottleneck technologies that limit this solution are full-element perception and occlusion judgment under free viewing angle, robust object matching method. To address the above problems, This paper proposes a free-viewpoint-based element perception and state recognition scheme. An improved structure estimation model is adopted to establish a bridge between virtual and actual mapping under the support of small-sample data, and all elements are located and occlusion analyzed by a 3D model-constrained view evolution algorithm. In addition, a hierarchy matching and optimization method is established to complete visual analysis. Experimental results show that this scheme performs well in structure estimation, element localization, occlusion judgment, state recognition, and work efficiency, demonstrating high application value.
Learning the dynamics of a one-dimensional plasma model with graph neural networks
Authors: Carvalho Diogo D , Ferreira Diogo R , Silva Luís O 
Published: May 2024

Abstract
We explore the possibility of fully replacing a plasma physics kinetic simulator with a graph neural network-based simulator. We focus on this class of surrogate models given the similarity between their message-passing update mechanism and the traditional physics solver update, and the possibility of enforcing known physical priors into the graph construction and update. We show that our model learns the kinetic plasma dynamics of the one-dimensional plasma model, a predecessor of contemporary kinetic plasma simulation codes, and recovers a wide range of well-known kinetic plasma processes, including plasma thermalization, electrostatic fluctuations about thermal equilibrium, and the drag on a fast sheet and Landau damping. We compare the performance against the original plasma model in terms of run-time, conservation laws, and temporal evolution of key physical quantities. The limitations of the model are presented and possible directions for higher-dimensional surrogate models for kinetic plasmas are discussed.
Examining Links Between Distinct Affective States and Tobacco Lapse During a Cessation Attempt Among African Americans: A Cohort Study
Authors: Jones Dusti R , Potter Lindsey N , Lam Cho Y , Schlechter Chelsey R , Nahum-Shani Inbal , Fagundes Christopher , Wetter David W 
Published: May 2024

Abstract

Background
Affect states are posited to play a pivotal role in addiction-related processes, including tobacco lapse (i.e., smoking during a quit attempt), and distinct affective states (e.g., joy vs. happiness) may differentially influence lapse likelihood. However, few studies have examined the influence of distinct affective states on tobacco lapse.

Purpose
This study examines the influence of 23 distinct affect states on tobacco lapse among a sample of tobacco users attempting to quit.

Methods
Participants were 220 adults who identified as African American (50% female, ages 18–74). Ecological momentary assessment was used to assess affect and lapse in real-time. Between and within-person associations testing links between distinct affect states and lapse were examined with multilevel modeling for binary outcomes.

Results
After adjusting for previous time’s lapse and for all other positive or negative affect items, results suggested that at the between-person level, joy was associated with lower odds of lapse, and at the within-person level, attentiveness was associated with lower odds of lapse. Results also suggested that at the between-person level, guilt and nervous were associated with higher odds of lapse, and at the within-person level, shame was associated with higher odds of lapse.

Conclusions
The present study uses real-time, real-world data to demonstrate the role of distinct positive and negative affects on momentary tobacco lapse. This work helps elucidate specific affective experiences that facilitate or hinder the ability to abstain from tobacco use during a quit attempt.
The road less traveled: Developing pharmacist clinician-scientists through divergent training pathways
Authors: Forehand Christy , Hamblin Susan , Cook Aaron M , Cain Jeff , Somanath Payaningal R , Stollings Joanna L 
Published: May 2024

Abstract

Purpose
Professional organizations have emphasized the growing need for pharmacists to possess advanced research skills; however, there is a scarcity of training programs aimed at nurturing clinician-scientists. This report outlines 3 critical care–focused research programs, each offering a unique approach to training clinician-scientists.

Summary
Limited resources and formalized programs are available to bridge the gap between the demand for and availability of skilled clinician-scientists. Several programs have stepped forward to share their experiences in establishing and executing training initiatives aimed at cultivating skilled clinician-scientists in the critical care practice space.

Conclusion
Enhancing the development of clinician-scientists for clinical and translational research is necessary in the critical care clinical pharmacy community.
Artificial Intelligence, Genuine Outcome: Analysis of 72 Consecutive Cases of Subfascial Augmentation Mastopexy With Smooth Round Implants Supported by P4HB Scaffold
Authors: Bistoni Giovanni , Sofo Francesco , Cagli Barbara , Buccheri Ernesto Maria , Mallucci Patrick 
Published: May 2024

Abstract

Background
Ptosis recurrence often leads to unsatisfactory results after mastopexy, even more so when additional stress is provided by implants on compromised native tissue. The poly-4-hydroxybutyrate(P4HB) scaffold (GalaFLEX) with its favorable safety profile and proven long-term mechanical strength represents a preferred option for soft tissue support.

Objectives
The primary endpoint was assessment of lower pole stretch from the early postoperative period up to 3 years.

Methods
Out of 151 patients who underwent surgery by G.B. from March 2020 to December 2023, a total of 72 with a 12-month-mininum follow-up who had primary (46) or secondary (26) augmentation mastopexy with subfascial round smooth implants and P4HB scaffold support were included in the study. Three-dimensional artificial intelligence software was utilized for all measurements. Further analysis included evaluation of ptosis recurrence and all complications.

Results
No recurrent ptosis, bottoming out, implant displacement, or capsular contracture was reported during follow-up (mean, 24.8 months). The lower pole arch's elongation was 8.04% and 9.44% at 1 and 3 years respectively, comparing favorably with previous reports. Statistically significant correlation (P &lt; .05) between implant size and lower pole stretch was noted, this being greater for larger implants (&gt; 400 cc; P = .0011) and primary cases (P = .1376). Progressive volume redistribution from upper to lower pole was observed in the first year, with substantial stability thereafter.

Conclusions
This is the largest published series reporting long-term results (up to 45 months) in mastopexy augmentation with GalaFLEX, suggesting its supportive role in lower pole stability even in the setting of concurrent breast augmentation with smooth implants in a subfascial plane.

Level of Evidence: 4
Frequent oil baths and skin barrier during infancy in the PreventADALL study
Authors: Rehbinder Eva Maria , Wärnberg Gerdin Sabina , Hoyer Angela , Bradley Maria , Lødrup Carlsen Karin C , Granum Berit , Hedlin Gunilla , Jonassen Christine Monceyron , Leblanc Marissa , Nordlund Björn , Rudi Knut , Skjerven Håvard O , Staff Anne Cathrine , Vettukattil Riyas , Söderhäll Cilla 
Published: May 2024

Abstract

Background
In the general population randomized controlled trial PreventADALL, frequent emollient bath additives from 2 weeks of age did not prevent atopic dermatitis, while the effect on skin barrier function throughout infancy is not established.

Objectives
The primary aim of this exploratory substudy was to assess the effect of mineral-based oil baths on transepidermal water loss (TEWL) and dry skin through infancy, and secondarily to explore if filaggrin (FLG) mutations modified the effect.

Methods
Overall, 2153 infants were included and randomized to either the ‘Skin intervention’ (SI) group (n = 995) (oil bath 4 times weekly from 2 weeks through 8 months) or ‘No skin intervention’ (NSI) group (n = 1158), with TEWL measurements at 3, 6 and/or 12 months of age. Information on FLG mutation status was available for 1683 of these infants. Effects of the skin intervention on TEWL and dry skin through infancy were assessed by mixed-effects regression modelling. Background characteristics and protocol adherence were collected from electronic questionnaires, birth records and weekly diaries.

Results
The TEWL (95% confidence interval) was on average 0.42 g m–2 h–1 (0.13–0.70, P = 0.004) higher in the SI group compared with the NSI group through the first year of life, with significantly higher levels at 3 months [8.6 (8.3–9.0) vs. 7.6 (7.3–7.9)], but similar at 6 and 12 months. Dry skin was observed significantly more often in the NSI group compared with the SI group at 3 months (59% vs. 51%) and at 6 months of age (63% vs. 53%), while at 12 months of age, the difference was no longer significant. At 3 months, the TEWL of FLG mutation carriers was similar to the TEWL in the SI group. No interaction between SI and FLG mutation was found in the first year of life.

Conclusions
Infants given frequent oil baths from 2 weeks of age had reduced skin barrier function through infancy compared with controls, largely attributed to higher TEWL at 3 months of age, while the skin at 3 and 6 months appeared less dry in infants subjected to the skin intervention.
Characterization in the rat of the individual tendency to rely on alcohol to cope with distress and the ensuing vulnerability to drink compulsively
Authors: Marti-Prats Lucia , Belin David 
Published: May 2024

Abstract
Only some vulnerable individuals who recreationally drink alcohol eventually develop the compulsive drinking pattern that characterizes alcohol use disorder. A new frontier in biomedical research lies in understanding the neurobehavioural mechanisms of this individual vulnerability, a necessary step towards developing novel effective therapeutic strategies. Translational research has been hindered by the lack of valid, reliable and robust approaches that enable the study of the influence of the reliance on alcohol to cope with stress or self-medicate negative emotional states on the subsequent transition to alcohol use disorder. We have therefore developed a behavioural task in the rat that enables the investigation of the neural and cellular basis of the exacerbation of the vulnerability to develop compulsive alcohol drinking by the use of alcohol to develop an adjunctive, anxiolytic, polydipsic drinking behaviour in a schedule-induced polydipsia procedure. Hence, in our task, alcohol is introduced in the schedule-induced polydipsia context after several weeks of training with water so that rats are exposed to alcohol for the first time in a distressing context and learn to drink alcohol as a coping strategy. Capitalizing on this protocol, we have consistently been able to identify a subpopulation of rats that were unable to learn to cope with negative states by drinking water and relied on alcohol to do so. This maladaptive reliance on alcohol drinking to cope with distress has been shown to be associated with an exacerbation of the subsequent transition to compulsive drinking. Furthermore, these vulnerable rats reached blood alcohol levels comparable to that of intoxication in humans, thereby developing two key features of alcohol use disorder, namely excessive alcohol intake and compulsive drinking. Altogether, this behavioural task provides a novel and unique tool for the investigation of the neurobehavioural mechanisms underlying the exacerbation of the individual vulnerability to developing compulsive alcohol drinking by the use of alcohol as a strategy to cope with distress, and for the evaluation of the efficacy of potential therapeutic strategies in a personalized medicine approach. This procedure, which focuses on an understudied but key factor of the development of alcohol use disorder, may become widely used as it benefits the fields of alcohol, emotion regulation and stress, the interest in which has substantially increased since the evidence of a profound exacerbation of alcohol use and alcohol-related negative consequences by the distress and social isolation engendered by the various measures implemented worldwide in response to the COVID-19 pandemic.
Drug-eluting balloon to treat immediate post-coronary artery bypass grafting ST-elevation myocardial infarction: a case report
Authors: Shah Muhammad Usman , Haider Muhammad Anis , Poudyal Krishna , Loubani Mahmoud , Naqvi Syed Yaseen 
Published: May 2024

Abstract

Background
Coronary artery bypass graft (CABG) surgery represents a major cardiovascular operation and may be associated with post-operative ST-elevation myocardial infarction (STEMI) due to graft failure. This is challenging to diagnose and treat as the implanted grafts may be prone to complications when treated percutaneously with drug-eluting stents.

Case summary
A man in his 60 s underwent CABG and developed new persistent ST elevations of 2 mm in anterior leads with no significant chest pain, although, administered with intravenous opiates post-operatively. Transthoracic echocardiography was non-diagnostic. Invasive angiography performed emergently showed a thrombotic occlusion of the mid-left anterior descending artery at the site of the anastomosis with the left internal mammary artery (LIMA) graft. Intervention via the graft was considered high risk of complications, therefore, native coronary arteries were used to approach the occlusion, which was successfully cleared with a combination balloon angioplasty with a semi-compliant and then a drug-eluting balloon. The LIMA started working again with the resolution of ST elevation and no immediate complications.

Discussion
Early post-operative ST elevations in continuous leads should not be ignored as they often may be the only feature of new-onset STEMI. Drug-eluting balloons represent a feasible and possibly safer option than drug-eluting stents to treat these conditions.
Comparative effects of different antiplatelet strategies in carriers of CYP2C19 loss-of-function alleles: a network meta-analysis
Authors: Galli Mattia , Occhipinti Giovanni , Benenati Stefano , Laborante Renzo , Ortega-Paz Luis , Franchi Francesco , D'Amario Domenico , Nerla Roberto , Castriota Fausto , Frati Giacomo , Biondi-Zoccai Giuseppe , Sciarretta Sebastiano , Angiolillo Dominick J 
Published: May 2024

Abstract

Background
Carriers of cytochrome 2C19 (CYP2C19) loss-of-function (LoF) alleles treated with clopidogrel have impaired drug metabolism, resulting in reduced active metabolite levels, high platelet reactivity (HPR), and an increased risk of thrombotic events. Several alternative antiplatelet therapies have been proposed to overcome HPR in these patients, but their comparative effects remain poorly explored.

Methods
Randomized controlled trials (RCTs) comparing different oral antiplatelet therapies in carriers of CYP2C19 LoF alleles undergoing percutaneous coronary interventions (PCI) were included. A frequentist network meta-analysis was conducted to estimate mean difference (MD) or odds ratios and 95% confidence intervals (CI). The primary outcome was platelet reactivity assessed by VerifyNow and reported as P2Y12 reaction unit (PRU). The secondary outcome was the rate of HPR. Standard dose of clopidogrel (75 mg daily) was used as a reference treatment.

Results
A total of 12 RCTs testing 6 alternative strategies (i.e. clopidogrel 150 mg, prasugrel 3.75 mg, 5 mg, and 10 mg, ticagrelor 90 mg bid, and adjunctive cilostazol 100 mg bid) were included in the network. Compared with standard-dose clopidogrel, the greatest reduction in PRU was observed with prasugrel 10 mg (MD −127.91; 95% CI −141.04; −114.78) and ticagrelor 90 mg bid (MD −124.91; 95% CI −161.78; −88.04), followed by prasugrel 5 mg (MD −76.33; 95% CI −98.01; −54.65) and prasugrel 3.75 mg (MD −73.00; 95% CI −100.28; −45.72). Among other strategies, adjunctive cilostazol (MD −42.64; 95% CI −64.72; −20.57) and high-dose clopidogrel (MD −32.11; 95% CI −51.33; −12.90) were associated with a modest reduction in PRU compared with standard-dose clopidogrel.

Conclusion
Among carriers of CYP2C19 LoF alleles undergoing PCI, standard-dose prasugrel or ticagrelor are most effective in reducing platelet reactivity, while double-dose clopidogrel and additional cilostazol showed modest effects. Reduced-dose of prasugrel may represent a balanced strategy to overcome HPR without a significant increase in bleeding. The clinical implications of these pharmacodynamic findings warrant further investigation.
Taking Dworkin’s Legal Monism Seriously
Authors: Bustamante Thomas 
Published: May 2024

Abstract
In this review essay, I analyse two philosophical positions presented by Cormac Mac Amhlaigh in New Constitutional Horizons – namely, a pluralistic analytic legal theory, which offers a criterion of ‘individuation’ of legal systems in the context of transnational laws (to explain the relationship between domestic and international law), and a pluralistic account of constitutionalism, which understands the concept of ‘constitution’ and related political concepts in the context of transnational legal relationships (treating them as ‘interpretive concepts’ in the sense of Ronald Dworkin). My main target is not Mac Amhlaigh’s account of constitutionalism, with which I agree, but, rather, his analytic legal theory. After a brief summary of the former, to make explicit the interpretive methodology of the book, I respond to the latter in two ways: first, I present Dworkin’s argument to defend Hans Kelsen’s international legal monism against H.L.A. Hart’s objections, and, second, I argue that the analytic ambition to provide a test to distinguish sharply between municipal law and international law, treating them as separate while simultaneously valid systems, is unachievable. I end with a claim that Dworkin’s thesis of the unity of value entails a distinctive version of legal monism, which is more plausible than Kelsen’s traditional legal monism because it is not committed to a ‘linear’ or ‘hierarchical’ theory of law.
Mitral valve prolapse: arrhythmic risk during pregnancy and postpartum
Authors: Sabbag Avi , Aabel Eivind W , Castrini Anna Isotta , Siontis Konstantinos C , Laredo Mikael , Nizard Jacky , Duthoit Guillaume , Asirvatham Samuel , Sehrawat Ojasay , Kirkels Feddo P , van Rosendael Philippe J , Beinart Roy , Acha Moshe Rav , Peichl Petr , Lim Han S , Sohns Christian , Martins Raphael , Font Jonaz , Truong Nguyen N K , Estensen Mette , Haugaa Kristina H 
Published: May 2024

Abstract

Background and Aims
Arrhythmic mitral valve prolapse (AMVP) is linked to life-threatening ventricular arrhythmias (VAs), and young women are considered at high risk. Cases of AMVP in women with malignant VA during pregnancy have emerged, but the arrhythmic risk during pregnancy is unknown. The authors aimed to describe features of women with high-risk AMVP who developed malignant VA during the perinatal period and to assess if pregnancy and the postpartum period were associated with a higher risk of malignant VA.

Methods
This retrospective international multi-centre case series included high-risk women with AMVP who experienced malignant VA and at least one pregnancy. Malignant VA included ventricular fibrillation, sustained ventricular tachycardia, or appropriate shock from an implantable cardioverter defibrillator. The authors compared the incidence of malignant VA in non-pregnant periods and perinatal period; the latter defined as occurring during pregnancy and within 6 months after delivery.

Results
The authors included 18 women with AMVP from 11 centres. During 7.5 (interquartile range 5.8–16.6) years of follow-up, 37 malignant VAs occurred, of which 18 were pregnancy related occurring in 13 (72%) unique patients. Pregnancy and 6 months after delivery showed increased incidence rate of malignant VA compared to the non-pregnancy period (univariate incidence rate ratio 2.66, 95% confidence interval 1.23–5.76).

Conclusions
The perinatal period could impose increased risk of malignant VA in women with high-risk AMVP. The data may provide general guidance for pre-conception counselling and for nuanced shared decision-making between patients and clinicians.