bluuebunny/crossref_metadata_2025_split huggingface dataset:
DETERMINANTS OF INDICATIONS OF FRAUD IN THE FINANCIAL STATEMENTS OF BANKS LISTED ON THE BEI
Authors: Rodhiyuddin Muhammad , Daryatno Andreas Bambang 
Published: May 2024

Berdasarkan laporan Association of Certified Fraud Examiners (ACFE) 2022, industri perbankan dan jasa keuangan mempunyai beban tertinggi dari seluruh kelompok industri yaitu sebesar 22,3%. Penting untuk memahami faktor-faktor apa saja yang mempengaruhi kecurangan laporan keuangan agar pemangku kepentingan dapat peduli untuk meningkatkan kualitas laporan keuangan. Penelitian ini bertujuan untuk menganalisis pengaruh fraud diamond terhadap kecurangan laporan keuangan. Fraud diamond terdiri dari elemen tekanan (pressure), kesempatan (opportunity), rasionalisasi (rationalization), dan kemampuan (capability). Penelitian ini penting untuk dilakukan agar diketahui faktor-faktor apa saja yang berpengaruh terhadap kecurangan laporan keuangan sehingga menjadi perhatian bagi stakeholders untuk peningkatan kualitas laporan keuangan. Teknik pengаmbilаn sаmpel dilаkukаn secаrа purposive sаmpling, Data yang digunakan dalam penelitian adalah data sekunder pada perusahaan Bank Umum Syariah yang Terdaftar di OJK 2016-2022, Analisa data menggunakan alat bantu statistik SPSS 23. Hasil penelitian menunjukkan bahwa secara parsial Tekanan dengan proksi rasio leverage, Tekanan dengan proksi rasio sales, Kesempatan dengan proksi porsi anggota independen dalam dewan komisaris, Kemampuan dengan proksi pergantian direksi tidak berpengaruh terhadap kecurangan laporan keuangan. Sedangkan Kesempatan dengan proksi porsi anggota independen dalam komite audit, Rasionalisasi dengan proksi total penghasilan akrual berpengaruh negatif terhadap kecurangan laporan keuangan.

Based on the Association of Certified Fraud Examiners (ACFE) 2022 report, the banking and financial services industry has the highest burden of all industry groups at 22.3%. It is important to understand what factors influence financial statement fraud so that stakeholders can care about improving the quality of financial statements. This study aims to analyze the effect of fraud diamond on financial statement fraud. Fraud diamond consists of elements of pressure, opportunity, rationalization, and capability. This research is important to do so that it is known what factors affect financial statement fraud so that it becomes a concern for stakeholders to improve the quality of financial statements. The technique of selecting samples is carried out by purposive sampling, the data used in the study is secondary data on Islamic Commercial Bank companies registered with OJK 2016-2022, data analysis using SPSS 23 statistical aids. The results showed that partially Pressure with proxy leverage ratio, Pressure with proxy sales ratio, Opportunity with proxy portion of independent members in the board of commissioners, Ability with proxy change of directors has no effect on financial statement fraud. While Opportunity with the proxy of the portion of independent members on the audit committee, Rationalization with the proxy of total accrual income has a negative effect on fraudulent financial statements.
GENERATION Z IN ENERGY INDUSTRY: PARADIGM SHIFT IN ORGANIZATIONAL DYNAMICS
Authors: Asril Arifin , Perdhana Mirwan Surya 
Published: May 2024

Penelitian konseptual ini mengeksplorasi bagaimana sebaiknya perusahaan di industri energi melakukan pendekatan Manajemen Sumber Daya Manusia (SDM) yang berkelanjutan untuk Generasi Z. Peneliti menganalisis kesamaan dalam pendekatan ini dengan membandingkan hasil survey Industrial Report beberapa institusi terkemuka dengan jurnal penelitian empiris terkait Gen Z di industri energi. Ini memungkinkan perbandingan praktik dan perilaku SDM yang berkelanjutan dengan mempertimbangkan faktor-faktor yang memengaruhi elemen ekspektasi karir yang telah ditentukan. Pendekatan ini melibatkan perbandingan teknis berbagai literatur menggunakan konstruk yang telah ditentukan untuk mencapai tujuan penelitian. Mengingat keterbatasan studi dalam lingkungan organisasi dan industri yang serupa, harapannya adalah penelitian ini dapat memberikan wawasan baru bagi organisasi untuk menyiapkan strategi yang paling tepat dalam mendukung keberadaan karyawan Generasi Z di lingkungan industri energi yang kompetitif sekaligus memastikan kinerja optimal untuk mendukung program Pemerintah di masa depan.

This conceptual research explores how companies in the energy industry should approach Sustainable Human Resource Management (HRM) for Generation Z. The researcher analyze the similarities in these approaches by comparing survey results from Industrial Reports of several leading institutions with empirical research journals related to Gen Z in the energy industry. This enables a comparison of sustainable HRM practices and behaviors by considering factors that influence predetermined career expectation elements. This approach involves a technical comparison of various literature using predefined constructs to achieve the research objectives. Given the limitations of studies within similar organizational and industrial environments, the hope is this research able to provide new insights for organizations to devise the most appropriate strategies in supporting the presence of Generation Z employees in the competitive energy industry environment while ensuring optimal performance to support future Government programs.
Clinical outcomes of primary anterior cruciate ligament reconstruction using six-strand hamstring autograft
Authors: Shah Nisarg , Dodiya Hardik , Damor Rohit , Pachore Javahir 
Published: May 2024

Objectives:
Quadrupled and five-strand hamstring tendon (HT) autografts are commonly used in anterior cruciate ligament reconstruction (ACLR), but there is significant variability in graft diameter. The six-strand HT autograft has been introduced to increase graft diameter in patients with undersized HT grafts and may achieve better clinical outcomes. None of the studies has reported clinical outcomes following this technique in Indian patients. We investigated clinical outcomes in patients who underwent primary ACLR using a six-strand HT autograft technique with a minimum six-month follow-up.

Materials and Methods:
Fifty-five patients who underwent primary ACLR using six-strand HT autografts with interference screw fixation were included in the study. These patients were followed up at three and six months for the evaluation of clinical outcomes. Subjective evaluations included the TegnerLysholm score, anterior cruciate ligament-quality-of-life (ACL-QOL) score, and International Knee Documentation Committee (IKDC) subjective score. Laxity assessments of the knees were performed using the Lachman test and the pivot-shift test. Functional evaluation of the patients was performed with an overall IKDC objective score.

Results:
The mean IKDC subjective score was significantly improved at three-month (63.42 ± 5.38) and six-month (82.82 ± 7.49) follow-up after surgery (P < 0.05) when compared with pre-operative scores (50.55 ± 1.84). A similar finding was also noted with the Tegner-Lysholm score and ACL-QOL score in our study. All patients have achieved normal to near-normal functional outcomes at six months in our study without any major complications. The most commonly found complication was paresthesia (21.80%) in the present study.

Conclusion:
In the primary ACLR, six-strand hamstring autograft achieves similar clinical outcomes and complications as reported with four-strand or five-strand HT autografts. However, the percentages of patients who achieved normal to near-normal outcomes were higher in the present study (100%) as compared to earlier reported data using four-strand or five-strand HT autografts (~85%). The six-strand graft technique is a useful means of increasing graft diameter when faced with an undersized hamstring graft.
Acute hyponatremia post craniotomy resulting in a unilateral fixed and dilated pupil: A case study on diagnosis and management
Authors: Caldwell David J. , Scheer Justin K. , Umbach Gray , Aghi Manish K. 
Published: May 2024

Background:
Postoperative hyponatremia is a known complication of intracranial surgery, which can present with depressed mental status. Hyponatremia resulting in focal neurologic deficits is less frequently described.

Case Description:
We describe a patient who, after a bifrontal craniotomy for olfactory groove meningioma, developed acute hyponatremia overnight with a decline in mental status from Glasgow coma scale (GCS) score 15 to GCS 7 and a unilateral fixed dilated pupil. Head computed tomography showed expected postoperative changes without new acute or localizing findings, such as unilateral uncal herniation. The patient’s mental status and pupil immediately improved with the administration of mannitol; however, there was a subsequent decline in mental status with a preserved pupil later that morning. Hypertonic saline reversed the neurologic change, and the patient was eventually discharged without a neurologic deficit. Focal neurologic deficits need not always arise following a craniotomy from a postoperative hematoma, stroke, or other finding with radiographic correlate.

Conclusion:
Post-craniotomy hyponatremia should now be seen as a postoperative complication that can result in both a general neurologic decline in mental status, as well as with focal neurologic signs such as a fixed, dilated pupil, which can be reversed with hyperosmolar therapy and correction of the hyponatremia.
Effect of PDCA on Nursing Management
Authors: Yao Jinqin , Xian Xiaoyun 
Published: May 2024

Objective: To explore and analyze the effect of the plan-do-check-act (PDCA) cycle method in the nursing management of head nurses. Methods: 68 patients who were hospitalized in the general surgery department were used as research subjects. The patients were divided into an experimental group and a reference group, with 34 cases in each group, by drawing lots. The experimental group was managed with the PDCA method. The management satisfaction, nursing quality score, and nursing effect of both groups were compared with each other. Results: The patients in the experimental group were generally more satisfied with the nursing services compared to the reference group (P < 0.05), and the difference was statistically significant. Before the intervention, there was no statistically significant difference (P > 0.05) in the nursing quality scores such as ward safety management, nursing risk management, nursing document writing, rescue equipment management, and head nurse administrative management between the two groups. After the intervention, the experimental group had higher nursing quality scores. Furthermore, the nursing effects such as disease education, quality control, safety management, humanistic care, and service attitude in the experimental group were significantly better than those in the reference group (P < 0.05). Conclusion: The application of the PDCA method in nursing management can improve management satisfaction, nursing quality, and nursing effect.
Rehabilitasi Lahan Kritis Melalui Penerapan Four-Dimensional Agroforestry di Tenjolaya, Bogor, Jawa Barat
Authors: Hartoyo Adisti Permatasari Putri , Madani Hilmi Naufal , Muhammad Dimas Nur , Hasanah Asmaul , Ghalib Ammar , Alifioni Kintan 
Published: May 2024

Lahan kritis diakibatkan oleh penggunaan lahan yang tidak berkelanjutan dan berdampak pada menurunnya fungsi ekosistem lahan. Salah satu upaya rehabilitasi lahan kritis yang dapat dilakukan adalah melalui implementasi four-dimensional agroforestry (4D Agroforestry). Tujuan penelitian ini adalah i) merancang desain 4D Agroforestry, dan ii) menganalisis pertumbuhan tanaman jahe (Zingiber officinale), lada (Piper nigrum), kapulaga (Amomum cardamomum), dan cincau (Cyclea barbata Miers) di bawah naungan mahoni (Swietenia mahagony). Jumlah tanaman yang digunakan adalah 67 bibit jahe, 44 bibit lada, 187 bibit cincau, dan 65 bibit kapulaga, sehingga totalnya adalah 363 bibit tanaman dengan durasi pengamatan adalah 4 MST. Implementasi 4D Agroforestry menjadi alternatif upaya optimalisasi pengelolaan lahan dengan memanfaatkan 4 dimensi, yakni i) dimensi length (panjang) dengan penanaman mahoni, ii) dimensi width dengan penanaman cincau (C. barbata), iii) dimensi height (tinggi) dengan penanaman lada (P. nigrum), singkong (M. esculenta), jahe (Z. officinale), dan kapulaga (Amomum cardamomum), serta iv) dimensi time (waktu) untuk produksi jangka pendek (produksi dari tanaman singkong, cincau, jahe, dan kapulaga), menengah (produksi dari tanaman lada), serta panjang (produksi dari kayu mahoni) untuk mencapai produksi berkelanjutan. Tanaman kapulaga menghasilkan pertumbuhan terbaik pada parameter pertambahan tinggi (15,28 cm) dan persen hidup (98.46%) setelah 4 MST.
Kata kunci: agroforestri, petani, rehabilitasi
Pengaruh Persepsi Kualitas, Persepsi Nilai, Persepsi Kepuasan dan Persepsi Diferensiasi terhadap Kesetiaan Merek yang Dimediasi oleh Kepercayaan Merek pada Merek Polki
Authors: Pramana Vina , Wardhana Ali 
Published: May 2024

<p align="center"><em>Abstract</em></p><p><em>The development of household cleaning products continues to expand from year to year creating a potential for companies to increase the number of consumers through quality perception, value perceptions, satisfaction perceptions and differentiation perceptions. The study aims to examine the influence of quality perceptions, value perceptions and satisfaction perceptions on brand loyalty mediated by brand trust in the POLKI brand. The sample in this study had 181 respondents who met the criteria. In this study, data is being processed using Smart PLS 3.0. The results of this study show that brand trust has a significant influence on brand loyalty. There is a significant impact between quality perception, value perception and satisfaction perception on brand trust. There are insignificant influences between the perception of quality, appreciation of value, satisfaction and differentiation perceptions of brand loyality. And there is a minor influence between differential perceptions and brand confidence. In addition, there are significant influences among quality perceptions, appreciations of value and satisfactions perceptions on brand faith mediated by brand trusts. </em></p>
Clinical Evidence for GLP-1 Receptor Agonists in Alzheimer’s Disease: A Systematic Review
Authors: Liang Yulin , Doré Vincent , Rowe Christopher C. , Krishnadas Natasha 
Published: May 2024

Background: Alzheimer’s disease (AD) is the most common cause of dementia. While preclinical studies have shown benefits of glucagon-like peptide 1 receptor agonists (GLP-1 RA) in targeting core AD pathology, clinical studies are limited. Objective: A systematic review was performed to evaluate GLP-1 RAs in AD for their potential to target core AD pathology and improve cognition. Methods: Searches were conducted via three different databases (PubMed, Embase, and Cochrane Library). Search terms included Medical Subject Headings (MeSH) terms: ‘glucagon-like peptide 1 receptor agonist’ and ‘Alzheimer’s disease’, as well as entry terms ‘GLP-1 RA’, ‘AD’, and three types of GLP-1 RA: ‘liraglutide’, ‘exenatide’, and ‘lixisenatide’. Results: A total of 1,444 studies were screened. Six articles that met criteria were included (four randomized control trials [RCTs] and two protocol studies). Two RCTs with amyloid-β and tau biomarker endpoints did not observe an end of treatment difference between the placebo and treated groups. In three RCTs with cognitive endpoints, there was no end of treatment difference between placebo and treated groups. GLP-1 RA showed metabolic benefits, such as lower body mass index and improved glucose levels on oral glucose tolerance tests in treated groups. GLP-1 RA may mitigate the decline in cerebral glucose metabolism and show enhanced blood-brain glucose transport capacity using 18F-FDG PET, however, more data is needed. Conclusions: GLP-1 RA therapy did not alter amyloid-β and tau biomarkers nor show improvements in cognition but showed potential metabolic and neuroprotective benefits.
Acute Hyperglycemia Induced by Hyperglycemic Clamp Affects Plasma Amyloid-β in Type 2 Diabetes
Authors: Rolandsson Olov , Tornevi Andreas , Steneberg Pär , Edlund Helena , Olsson Tommy , Andreasson Ulf , Zetterberg Henrik , Blennow Kaj 
Published: May 2024

Background: Individuals with type 2 diabetes (T2D) have an increased risk of cognitive symptoms and Alzheimer’s disease (AD). Mis-metabolism with aggregation of amyloid-β peptides (Aβ) play a key role in AD pathophysiology. Therefore, human studies on Aβ metabolism and T2D are warranted. Objective: The objective of this study was to examine whether acute hyperglycemia affects plasma Aβ1–40 and Aβ1–42 concentrations in individuals with T2D and matched controls. Methods: Ten participants with T2D and 11 controls (median age, 69 years; range, 66–72 years) underwent hyperglycemic clamp and placebo clamp (saline infusion) in a randomized order, each lasting 4 hours. Aβ1–40, Aβ1–42, and insulin-degrading enzyme (IDE) plasma concentrations were measured in blood samples taken at 0 and 4 hours of each clamp. Linear mixed-effect regression models were used to evaluate the 4-hour changes in Aβ1–40 and Aβ1–42 concentrations, adjusting for body mass index, estimated glomerular filtration rate, and 4-hour change in insulin concentration. Results: At baseline, Aβ1–40 and Aβ1–42 concentrations did not differ between the two groups. During the hyperglycemic clamp, Aβ decreased in the control group, compared to the placebo clamp (Aβ1–40: p = 0.034, Aβ1–42: p = 0.020), IDE increased ( p = 0.016) during the hyperglycemic clamp, whereas no significant changes in either Aβ or IDE was noted in the T2D group. Conclusions: Clamp-induced hyperglycemia was associated with increased IDE levels and enhanced Aβ40 and Aβ42 clearance in controls, but not in individuals with T2D. We hypothesize that insulin-degrading enzyme was inhibited during hyperglycemic conditions in people with T2D.
TLR4/Rac1/NLRP3 Pathway Mediates Amyloid-β-Induced Neuroinflammation in Alzheimer’s Disease
Authors: Zhu Mengxin , Liu Yang , Chen Chen , Chen Hao , Ni Wanyan , Song Yuanjian , Lv Bingchen , Hua Fang , Cui Guiyun , Zhang Zuohui 
Published: May 2024

Background: Neuroinflammation plays a crucial part in the initial onset and progression of Alzheimer’s disease (AD). NLRP3 inflammasome was demonstrated to get involved in amyloid-β (Aβ)-induced neuroinflammation. However, the mechanism of Aβ-triggered activation of NLRP3 inflammasome remains poorly understood. Objective: Based on our previous data, the study aimed to identify the downstream signals that bridge the activation of TLR4 and NLRP3 inflammasome associated with Aβ. Methods: BV-2 cells were transfected with TLR4siRNA or pretreated with a CLI-095 or NSC23766, followed by Aβ1–42 treatment. APP/PS1 mice were injected intraperitoneally with CLI-095 or NSC23766. NLRP3 inflammasome and microglia activation was detected with immunostaining and western blot. G-LISA and Rac1 pull-down activation test were performed to investigate the activation of Rac1. Real-time PCR and ELISA were used to detect the inflammatory cytokines. Aβ plaques were assessed by western blotting and immunofluorescence staining. Morris water maze test was conducted to determine the spatial memory in mice. Results: Rac1 and NLRP3 inflammasome were activated by Aβ in both in vitro and in vivo experiments. Inhibition of TLR4 reduced the activity of Rac1 and NLRP3 inflammasome induced by Aβ1–42. Furthermore, inhibition of Rac1 blocked NLRP3 inflammasome activation mediated by TLR4. Blocking the pathway by CLI095 or NSC23766 suppressed Aβ1–42-triggered activation of microglia, reduced the expression of pro-inflammatory mediators and ameliorated the cognition deficits in APP/PS1 mice. Conclusions: Our study demonstrated that TLR4/Rac1/NLRP3 pathway mediated Aβ-induced neuroinflammation, which unveiled a novel pathway and key contributors underlying the pathogenic mechanism of Aβ.
Association of Age with Dual-Task Objective Cognitive Indicators and Gait Parameters in Older Adults
Authors: Wang Linlin , Zhang Xuezhen , Wang Lei , Guo Miaomiao , Yang Qihang , Chen Xiaogang , Sha Hong 
Published: May 2024

Background: Early recognition of dementia like Alzheimer’s disease is crucial for disease diagnosis and treatment, and existing objective tools for early screening of cognitive impairment are limited. Objective: To investigate age-related behavioral indicators of dual-task cognitive performance and gait parameters and to explore potential objective markers of early cognitive decline. Methods: The community-based cognitive screening data was analyzed. Hierarchical cluster analysis and Pearson correlation analysis were performed on the 9-item subjective cognitive decline (SCD-9) scores, walking-cognitive dual-task performance, walking speed, and gait parameters of 152 participants. The significant differences of indicators that may related to cognitive decline were statistically analyzed across six age groups. A mathematical model with age as the independent variable and motor cognition composite score as the dependent variable was established to observe the trend of motor cognition dual-task performance with age. Results: Strong correlation was found between motor cognitive scores and SCD and age. Gait parameters like the mean value of ankle angle, the left-right difference rate of ankle angle and knee angle and the coefficient of variation of gait cycle showed an excellent correlation with age. Motor cognition scores showed a decreasing trend with age. The slope of motor cognition scores with age after 50 years ( k = –1.06) was six times higher than that before 50 years ( k = –0.18). Conclusions: Cognitive performance and gait parameters in the walking-cognitive dual-task state are promising objective markers that could characterize age-related cognitive decline.
TDP-43 Is Associated with Subiculum and Cornu Ammonis 1 Hippocampal Subfield Atrophy in Primary Age-Related Tauopathy
Authors: Youssef Hossam , Gatto Rodolfo G. , Pham Nha Trang Thu , Petersen Ronald C. , Machulda Mary M. , Reichard R. Ross , Dickson Dennis W. , Jack Clifford R. , Whitwell Jennifer L. , Josephs Keith A. 
Published: May 2024

Background: TAR DNA binding protein 43 (TDP-43) has been shown to be associated with whole hippocampal atrophy in primary age-related tauopathy (PART). It is currently unknown which subregions of the hippocampus are contributing to TDP-43 associated whole hippocampal atrophy in PART. Objective: To identify which specific hippocampal subfield regions are contributing to TDP-43-associated whole hippocampal atrophy in PART. Methods: A total of 115 autopsied cases from the Mayo Clinic Alzheimer Disease Research Center, Neurodegenerative Research Group, and the Mayo Clinic Study of Aging were analyzed. All cases underwent antemortem brain volumetric MRI, neuropathological assessment of the distribution of Aβ (Thal phase), and neurofibrillary tangle (Braak stage) to diagnose PART, as well as assessment of TDP-43 presence/absence in the amygdala, hippocampus and beyond. Hippocampal subfield segmentation was performed using FreeSurfer version 7.4.1. Statistical analyses using logistic regression were performed to assess for associations between TDP-43 and hippocampal subfield volumes, accounting for potential confounders. Results: TDP-43 positive patients ( n = 37, 32%), of which 15/15 were type-α, had significantly smaller whole hippocampal volumes, and smaller volumes of the body and tail of the hippocampus compared to TDP-43 negative patients. Subfield analyses revealed an association between TDP-43 and the molecular layer of hippocampal body and the body of cornu ammonis 1 (CA1), subiculum, and presubiculum regions. There was no association between TDP-43 stage and subfield volumes. Conclusions: Whole hippocampal volume loss linked to TDP-43 in PART is mainly due to volume loss occurring in the molecular layer, CA1, subiculum and presubiculum of the hippocampal body.