bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraprofessional boundary crossing in acute paediatric care: A rich journey for general practice and paediatric residents
Authors: van Schie Rosalin , Coolen Ester , van Tuijl Anne , van der Velden Janielle , Thoonen Bart , Scherpbier‐de Haan Nynke 
Published: May 2024

AbstractBackgroundAchieving optimal collaboration between general practitioners and hospital‐based critical care doctors is vital yet challenging, necessitating targeted collaborative training during residency. Despite apparent benefits, implementing intraprofessional learning faces constraints. Understanding its occurrence is crucial for engaging and educating residents. Considering boundaries' learning potential, we developed and evaluated an educational programme for general practitioner (GP) and paediatric (P) residents in paediatric emergency care based on Akkerman's Boundary Crossing Theory. The study investigated how intraprofessional learning mechanisms occurred and what learning conditions facilitated or impeded learning of GP and P residents, aiming to optimise educational programme design for intraprofessional collaboration.MethodsWe developed an educational programme with three activities: joint medical assessments of paediatric patients in each other's context, mutually mini‐Clinical Evaluation Exercises (mini‐CEXs) about intraprofessional collaboration skills and educational meetings about collaborative care. We performed a qualitative study with a constructivist approach to explore experiences of the programme. We conducted focus group interviews and analysed mini‐CEXs, utilising Boundary Crossing theory for template analysis.ResultsTen GP and eight P residents participated in our study. Learning mechanisms of identification and coordination dominated the joint medical assessments. Mini‐CEXs stimulated reflection. Educational meetings with supervisors about intraprofessional barriers initiated transformation. Facilitated learning conditions were bidirectional crossing, enthusiastic supervisors, residents being familiar with each other, clear mini‐CEX design and authentic paediatric cases. Unclear mutual expectations during joint medical assessments impeded learning of residents.ConclusionsWorking in each other's context triggers learning mechanisms of identification, coordination and reflection, forming the basis for intraprofessional learning in paediatric emergency care for GP and P residents. For development of new collaboration practices, supervisors are necessary to translate reflection into transformation. Mutual responsibilities and expectations should be made more explicit to create a safer intraprofessional learning environment. Our findings extend to other medical training contexts, leveraging boundaries for learning.
Bureaucratic redundancy and administrative burden: Evidence from public‐private partnerships (PPPs) in China
Authors: Xiong Wei , Wang Feng , Christensen Tom , Casady Carter B. 
Published: May 2024

AbstractAdministrative burden is experienced by both individuals and businesses when dealing with government entities. While previous literature suggests administrative burden arises from the deliberate choices of political actors, this study highlights how bureaucratic redundancies also lead to administrative burden. Using a dataset of public‐private partnerships (PPPs) in China, this study explored the influence of bureaucratic redundancy on administrative burden, in particular contractors' compliance costs caused by PPP regulations. The analysis found that bureaucratic redundancy has a positive and curvilinear relationship with compliance costs, which in turn has a positive relationship with the likelihood of PPP contract termination. These results hold even after controlling for political and economic factors. Nevertheless, such effects can be mitigated through government reforms, such as jurisdictional reduction and legislative centralization.
The E3 ubiquitin ligase COP1 regulates salt tolerance via GIGANTEA degradation in roots
Authors: Ji Myung Geun , Khakurel Dhruba , Hwang Ji‐Won , Nguyen Cam Chau , Nam Byoungwoo , Shin Gyeong‐Im , Jeong Song Yi , Ahn Gyeongik , Cha Joon‐Yung , Lee Sung‐Ho , Park Hee Jin , Kim Min Gab , Yun Dae‐Jin , Rubio Vicente , Kim Woe‐Yeon 
Published: May 2024

AbstractExcess soil salinity significantly impairs plant growth and development. Our previous reports demonstrated that the core circadian clock oscillator GIGANTEA (GI) negatively regulates salt stress tolerance by sequestering the SALT OVERLY SENSITIVE (SOS) 2 kinase, an essential component of the SOS pathway. Salt stress induces calcium‐dependent cytoplasmic GI degradation, resulting in activation of the SOS pathway; however, the precise molecular mechanism governing GI degradation during salt stress remains enigmatic. Here, we demonstrate that salt‐induced calcium signals promote the cytoplasmic partitioning of CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), leading to the 26S proteasome‐dependent degradation of GI exclusively in the roots. Salt stress‐induced calcium signals accelerate the cytoplasmic localization of COP1 in the root cells, which targets GI for 26S proteasomal degradation. Align with this, the interaction between COP1 and GI is only observed in the roots, not the shoots, under salt‐stress conditions. Notably, the gi‐201 cop1‐4 double mutant shows an enhanced tolerance to salt stress similar to gi‐201, indicating that GI is epistatic to COP1 under salt‐stress conditions. Taken together, our study provides critical insights into the molecular mechanisms governing the COP1‐mediated proteasomal degradation of GI for salt stress tolerance, raising new possibilities for developing salt‐tolerant crops.
Cardiac function evaluation in children with spinal muscular atrophy: A case–control study
Authors: He Xiufang , Li Xuandi , Yan Mengzhen , Peng Huimin , Zhang Lili , Liang Yujian , Tang Wen , Li Shujuan 
Published: May 2024

AbstractBackgroundSpinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by degeneration of lower motor neurons, resulting in progressive muscle weakness and atrophy. However, little is known regarding the cardiac function of children with SMA.MethodsWe recruited SMA patients younger than 18 years of age from January 1, 2022, to April 1, 2022, in the First Affiliated Hospital of Sun Yat‐sen University. All patients underwent a comprehensive cardiac evaluation before treatment, including history taking, physical examination, blood tests of cardiac biomarkers, assessment of echocardiography and electrocardiogram. Age/gender‐matched healthy volunteers were recruited as controls.ResultsA total of 36 SMA patients (26 with SMA type 2 and 10 with SMA type 3) and 40 controls were enrolled in the study. No patient was clinically diagnosed with heart failure. Blood tests showed elevated values of creatine kinase isoenzyme M and isoenzyme B (CK‐MB) mass and high‐sensitivity cardiac troponin T (hs‐cTnT) in spinal muscular atrophy (SMA) patients. Regarding echocardiographic parameters, SMA children were detected with lower global left and right ventricular longitudinal strain, abnormal diastolic filling velocities of trans‐mitral and trans‐tricuspid flow. The results revealed no clinical heart dysfunction in SMA patients, but subclinical ventricular dysfunction was seen in SMA children including the diastolic function and myocardial performance. Some patients presented with elevated heart rate and abnormal echogenicity of aortic valve or wall. Among these SMA patients, seven patients (19.4%) had scoliosis. The Cobb's angles showed a significant negative correlation with LVEDd/BSA, but no correlation with other parameters, suggesting that mild scoliosis did not lead to significant cardiac dysfunction.ConclusionsOur findings warrant increased attention to the cardiac status and highlight the need to investigate cardiac interventions in SMA children.
Virtual speed dating: Utilizing online‐meeting platforms to study initial attraction and relationship formation
Authors: French Juliana E. , Bolton Lindsay J. , Meltzer Andrea L. 
Published: May 2024

AbstractThere is still much to learn about attraction and relationship formation. Here, we introduce an innovative method that utilizes modern technology to permit large‐scale, observational study of dyadic behavior that may yield new empirical insights into how people choose partners and form relationships: virtual speed dating. In doing so, we provide a methodological overview of a recent virtual speed‐dating study that we conducted, and we provide guidance for other scholars who wish to conduct such a study. Not only does virtual speed dating permit a feasible way to conduct large‐scale speed‐dating research and observe dyadic behavior during initial meeting and dating interactions, but it can benefit relationship science in myriad other ways, including the ability to (a) study novel research questions about first‐impression formation, romantic rivalries, and affiliative behaviors, (b) study diverse types of relationships, and (c) increase representation of diverse individuals in relationship science.
Narcissism and romantic relationship functioning: The mediating role of the desire for power
Authors: Zeigler‐Hill Virgil , Hicks Paxton , Brosch Nathan 
Published: May 2024

AbstractWe investigated the potential role played by the desire for power in the connections between narcissistic personality traits and indicators of romantic relationship functioning. In Study 1, we discovered that antagonistic narcissism had indirect connections with indicators of romantic relationship functioning via the desire for power. In Study 2, we observed actor associations in romantic couples. More specifically, antagonistic narcissism exhibited indirect links with romantic relationship functioning through the desire for power for both men and women. Additionally, partner associations emerged from these analyses. For women and men, their antagonistic narcissism had an indirect association with the romantic relationship functioning of their partners through their own desire for power. Furthermore, the antagonistic narcissism of women was associated with the romantic relationship functioning of both themselves and their male partners, mediated by the desire for power as reported by their male partners. The associations that emerged for the other narcissistic personality traits were somewhat weak and inconsistent across these studies. In our discussion, we explore how the concept of the desire for power can offer insights into understanding the complex dynamics often observed in romantic relationships characterized by certain aspects of narcissism.
Bacillus subtilis promotes plant phosphorus (P) acquisition through P solubilization and stimulation of root and root hair growth
Authors: Jensen Camilla Niketa Gadomska , Pang Janet Ka Yan , Gottardi Michele , Kračun Stjepan Krešimir , Svendsen Birgit Albrecht , Nielsen Kristian Fog , Kovács Ákos T. , Moelbak Lars , Fimognari Lorenzo , Husted Søren , Schulz Alexander 
Published: May 2024

AbstractBacteria can be applied as biofertilizers to improve crop growth in phosphorus (P)‐limited conditions. However, their mode of action in a soil environment is still elusive. We used the strain ALC_02 as a case study to elucidate how Bacillus subtilis affects dwarf tomato cultivated in soil‐filled rhizoboxes over time. ALC_02 improved plant P acquisition by increasing the size and P content of P‐limited plants. We assessed three possible mechanisms, namely root growth stimulation, root hair elongation, and solubilization of soil P. ALC_02 produced auxin, and inoculation with ALC_02 promoted root growth. ALC_02 promoted root hair elongation as the earliest observed response and colonized root hairs specifically. Root and root hair growth stimulation was associated with a subsequent increase in plant P content, indicating that a better soil exploration by the root system improved plant P acquisition. Furthermore, ALC_02 affected the plant‐available P content in sterilized soil differently over time and released P from native P pools in the soil. Collectively, ALC_02 exhibited all three mechanisms in a soil environment. To our knowledge, bacterial P biofertilizers have not been reported to colonize and elongate root hairs in the soil so far, and we propose that these traits contribute to the overall effect of ALC_02. The knowledge gained in this research can be applied in the future quest for bacterial P biofertilizers, where we recommend assessing all three parameters, not only root growth and P solubilization, but also root hair elongation. This will ultimately support the development of sustainable agricultural practices.
Rhizobial‐induced phosphatase GmPP2C61A positively regulates soybean nodulation
Authors: Gao Yongkang , Qu Dejie , Zhou Miaomiao , Tang Ruiheng , Ye Junjie , Li Xia , Wang Youning 
Published: May 2024

AbstractSymbiotic nitrogen fixation (SNF) is crucial for legumes, providing them with the nitrogen necessary for plant growth and development. Nodulation is the first step in the establishment of SNF. However, the determinant genes in soybean nodulation and the understanding of the underlying molecular mechanisms governing nodulation are still limited. Herein, we identified a phosphatase, GmPP2C61A, which was specifically induced by rhizobia inoculation. Using transgenic hairy roots harboring GmPP2C61A::GUS, we showed that GmPP2C61A was mainly induced in epidermal cells following rhizobia inoculation. Functional analysis revealed that knockdown or knock‐out of GmPP2C61A significantly reduced the number of nodules, while overexpression of GmPP2C61A promoted nodule formation. Additionally, GmPP2C61A protein was mainly localized in the cytoplasm and exhibited conserved phosphatase activity in vitro. Our findings suggest that phosphatase GmPP2C61A serves as a critical regulator in soybean nodulation, highlighting its potential significance in enhancing symbiotic nitrogen fixation.
Data governance for the ecological transition: An infrastructure perspective
Authors: Ducuing Charlotte 
Published: May 2024

AbstractThis article uses infrastructure studies to provide a critical analysis of the European Union's (EU) ambition to regulate data for the ecological transition. The EU's regulatory project implicitly qualifies data as an infrastructure for a better economy and society. However, current EU law does not draw all the logical consequences derived from this qualification of data as infrastructure, which is one main reason why EU data legislation for the ecological transition may not deliver on its high political expectations. The ecological transition does not play a significant normative role in EU data legislation and is largely overlooked in the data governance literature. By drawing inferences from the qualification of data as an infrastructure more consistently, the article opens avenues for data governance that centre the ecological transition as a normative goal.
Retrospective study of a pilot program focused on educating dental patients on human papillomavirus and vaccination in a hospital setting
Authors: Piscatelli Nicole , Claus Jonathan , George Devin , Schlecht Nicolas F. , Seserman Michael , Alvarado Alan , Sullivan Maureen , Frustino Jennifer 
Published: May 2024

AbstractIntroductionHuman papillomavirus (HPV) is an epidemic currently affecting 80 million people in the United States. The HPV virus can be passed from one person to another via sexual intercourse, oral sex, open mouth kissing and skin‐to‐skin contact. In some cases, the infection is not eliminated by the immune system and can cause cancer of the head and neck, cervix, anus, and genitals. There has been a rise in oropharyngeal cancer (OPC) associated with HPV, which can be missed on conventional dental screening examinations. Dentists should engage in promoting HPV vaccination as a primary measure for OPC prevention. The goal of this HPV pilot program was to educate and offer same day HPV vaccination to dental patients by using a multidisciplinary approach in a hospital setting.MethodsPatients 18 through 26 years of age who presented to the Erie County Medical Center's dental clinic were approached and educated on HPV. Eligible patients received a direct recommendation for the HPV vaccine. Those interested in same day vaccination were referred to the division of infectious diseases’ YOU Center for Wellness.A retrospective chart review was completed for patients who were HPV educated from March 5, 2020, through December 15, 2021. Charts were evaluated for age, sex, race, ethnicity, reason for visit, HPV vaccine referral, and HPV vaccine administration.Results326 patients were included in the chart review. The prominent sex, race, and ethnicity were male, Black or African American, and non‐Hispanic origin. The median age was 23. Most patients presented to the dental clinic for an emergency visit and were not previously vaccinated against HPV. 110 patients were unvaccinated, and 44 patients were referred to the division of infectious disease for same day vaccination. Of these 44, 24 patients initiated the vaccination process. Five patients received all three doses, three patients received two doses, and 16 patients received one dose.ConclusionThis pilot program successfully vaccinated 24 patients with at least a single dose of the HPV vaccine. This multidisciplinary model can be implemented in other health care settings.
Historically conjoined, religiously disjoined: Religion and Nigeria’s political trajectory since 1986
Authors: Eze Okonkwo C. , Alaku Emmanuel C. , Nwamuo Bright , Nwaoha Chimaroke C. , Ngwu Elias C. 
Published: May 2024

AbstractNigeria is a motley of about 250 ethnic nationalities spread across 36 states and the Federal Capital Territory. This omnibus political union rests on a twin tripod provided by the three major religions namely African Traditional Religion, Islam and Christianity as well as three major ethnic groups: Igbo; Hausa; and Yoruba, though these are not coterminous with the three religions. This study explores the intricate tapestries among religion, ethnicity and politics and its implication for nationhood in Nigeria. The study argues that this interface has created two laws and two nations in Nigeria between whom there is hardly any intercourse. It found entrenched, systematic segregation along ethno‐religious fault lines, and concludes that it is this deliberate exclusion of peoples from the plums of office that has engendered the recurring ethno‐religious upheavals and separatist agitations.
A geometry‐based method for visualizing time‐varying flow fields on web map platforms using texture polymorphism
Authors: Shu Yucheng , Tang Zihao , Zhang Yiming , Wen Yongning , Chen Min , Yue Songshan 
Published: May 2024

AbstractGlobal climate change has escalated flood risks, necessitating advanced hydrodynamic models for predicting watershed dynamics. Integrating flow‐field visualization with web maps offers a time‐sensitive, geographic context for sharing and understanding these dynamic changes virtually. Traditional methods use texture series on maps for flow visualization but fall short in interactive detail examination. Drawing geometric shapes directly on maps has been limited by low efficiency. Addressing the need for interactive visualization and efficiency, this study presents a texture polymorphism strategy for geometric visualization of time‐varying flow fields. This approach combines geometric style simulation with texture‐assisted computation, optimizing interactivity and performance on web map platforms. Our evaluation confirms that this method enhances usability and integration, ensuring high performance in visualizing flow dynamics.
Possibility and quality assessment in seafloor modeling relative to the sea surface using hybrid data
Authors: Idzikowska Magdalena , Pająk Katarzyna , Kowalczyk Kamil 
Published: May 2024

AbstractThe development of reliable seafloor topography models is a complex, multi‐track process, which is due to the diversity of available sets of data, their resolution, acquisition methods, complex seafloor forms, and the multitude of interpolation techniques. This article is aimed at assessing the suitability of different algorithms for seafloor modelling based on hybrid datasets (multi‐beam soundings and raster GEBCO models). The study involves the selection of optimum solutions as well as a comparative analysis of sea level change trends based on altimetric data. The study area relates to four forms of seafloor topography, namely the oceanic trench, the submarine canyon, the seamount region, and the undulating areas. The most reliable models were built by interpolating by the Kriging methods at a 0.01‐degree grid spacing. The smallest residues and the greatest correlation are found between models generated from all available sounding datasets. Raster GEBCO models can be an alternative in the additional model densification. The results show the following relationships: the greater the variation in the topography, the greater the divergence in the values of the sea level change trends. As for seamounts, hills, and folds, when the terrain rises rapidly, the trend values also increase and then decrease during the decline. Seafloor structure mapping enables the search for relationships between the seafloor topography and the changes occurring at the water surface.
Risk factors for the development of severe or very severe respiratory syncytial virus‐related lower respiratory tract infection in Indian infants: A cohort study in Melghat, India
Authors: Crow Rowena , Satav Ashish , Potdar Varsha , Satav Shilpa , Dani Vibhawari , Simões Eric A. F. 
Published: May 2024

AbstractObjectivesRespiratory syncytial virus (RSV) is undoubtedly the single most important cause of severe lower respiratory tract infection (LRTI) globally. While new prevention measures in young infants have become available, their use in developing countries is likely many years away. While risk factors for severe or very severe RSV LRTI in impoverished rural areas likely differ to urban areas, there are very few studies, especially those conducted in India, the major country contributing to the global burden of disease.MethodsActive surveillance for acute LRTI in enrolled infants and children <2 years of age, was conducted through weekly home visits in 93 villages of Melghat, India, from August 2016 to December 2020. Local hospitals and primary health centres were surveyed for admissions of enrolled subjects. Nasopharyngeal swabs were collected from children with severe, or very severe LRTIs and all who died, with RSV testing using nucleic acid tests at ICMR, National Institute of Virology Pune. Risk factors for both RSV associated and non‐RSV associated, severe and very severe LRTI were identified through univariate and multivariate logistic regression.ResultsThere were 483 severe or very severe RSV LRTI cases and 2807 non‐RSV severe or very severe LRTI infections in a cohort of 13,318 children. Weight for age z‐score ≤−2, the use of kerosene or wood for cooking, obtaining drinking water from a public tap and low gestational age significantly increased the risk of RSV LRTI. A higher wealth score index and water purification were protective. Comparison with non‐RSV LRTI showed male sex as an additional risk factor. The analysis highlighted the risk of kerosene use [OR = 17.8 (3.0–104.4) (p ≤ 0.001)] and [OR = 3.4 (0.8–14.4) (p ≤ 0.05)] for RSV and non‐RSV LRTIs, respectively.ConclusionsNutritional status and environmental air quality are predisposing factors for developing an RSV LRI in young children, factors which are amenable to environmental and behavioural interventions.