bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leprosy in transplant recipients: report of a case after liver transplantation and review of the literature
Authors: Trindade M.A.B. , Palermo M.L. , Pagliari C. , Valente N. , Naafs B. , Massarollo P.C.B. , D'Albuquerque L.A.C. , Benard G. 
Published: July 2010

M.A.B. Trindade, M. de Lourdes Palermo, C. Pagliari, N. Valente, B. Naafs, P.C.B. Massarollo, L.A.C. D'Albuquerque, G. Benard. Leprosy in transplant recipients: report of a case after liver transplantation and review of the literature. Transpl Infect Dis 2011: 13: 63–69. All rights reservedAbstract: Leprosy still is an important public health problem in several parts of the world including Brazil. Unlike the diseases caused by other mycobacteria, the incidence and clinical presentation of leprosy seems little affected in immunosuppressed patients. We report the first case, to our knowledge, of a liver transplant patient who developed multi‐bacillary leprosy. The patient presented with papules and infiltrated plaques with loss of sensation suggestive of leprosy 3.5 years after living‐related liver transplantation for autoimmune hepatitis. A skin biopsy showing non‐caseating macrophagic granulomas, neuritis, and intact acid‐fast bacilli on Fite‐Faraco stain, confirmed the diagnosis of borderline lepromatous leprosy. The donor of the liver did not show any evidence of leprosy. During follow‐up, the patient presented 2 episodes of upgrading leprosy type I reactions, 1 mild before leprosy treatment, and 1 moderate 3 months after receiving standard multi‐drug treatment (rifampicin, clofazimine, and dapsone). These reactions were accompanied by increase in liver function tests, especially of canalicular enzymes. This reaction occurred despite the patient's triple immunosuppression regimen. The moderate reaction was successfully treated with further immunosuppression (prednisone, 0.5 mg/kg). Currently, the patient is asymptomatic, off leprosy medication, with routine liver transplant follow‐up. The dilemmas in diagnosis and management of such a case are discussed and the literature on leprosy in transplant recipients is reviewed.
Die Forstentomologie in der russischen Zeitschrift “Lesnoje chosjaistwo” (Forstwirtschaft) Jahrgang 1957
Authors: BRAMMANIS L. 
Published: July 2010

TALALAJEV, E. V.: Bakteriologische Methode zur Bekämpfung des sibirischen Spinners. I, 36. (Aus dem Institut für Physiologie und Mikrobiologie der Universität Irkutsk.)GUKASJAN, A. B. und KOLOMIJEZ, N. G.: Versuch zur Bekämpfung des sibirischen Spinners mit Hilfe der Spinnerbazille. I, 38. (Aus der westsibirischen Filiale der Akademie der Wissenschaften der UdSSR).ROŽKOV, A. S. Brandgeschädigte Kicferndickungen: gefährliche Schädlingsherde. I, 71. (Aus der ostsibirischen Filiale der Akademie der Wissenschaften der UdSSR.)POKOZIJ, I. T.: Ein gefährlicher Eichenschädling. I, 72. (Aus dem landwirtschaftlichen Institut Charckov.)SINADSKIJ, J. V.: Schädlinge der Auenwälder im unteren Fluβlauf des Amu‐Darja. II, 24. (Aus dem Moskauer Forsttechnischen Institut.)DJADJEDSCHKO, N. P.: Verwendung der Muscardine Beauveria bassiana zur Bekämpfung von blattfressenden Insekten. II, 27.KUKOLEVSKIJ, A. K.: Bekämpfung der Lärchenblattwespe mit HCH‐Nebelpatronen. IV, 38.MISCHIN, A. V.: Die Waldzecke ein Überträger des Enzephalitis‐Virus. IV, 10. (Aus der Abteilung für Biologie des Medizinischen Institutes Ischevsk.)LOSINSKIJ, V. A.: Der Eichenspinner — ein Forstschädling im Süden der UdSSR. V, 40. (Aus dem Institut für Entomologie und Phytologie der Akademie der Wissenschaften der Ukrainischen SSR.)IVLIEV, L. A.: Über eine rationelle Benutzung von Beständen, die in Folge des Kiefernspinnerangriffes absterben. VI, 54. (Aus der fernöstlichen Filiale der Akademie der Wissenschaften der UdSSR.)ZINNOVSKIJ, J.: Feststellung der Verpuppungszeit bei Maikäferengerlingen. VI, 56. (Aus dem zoologischen Institut der Akademie der Wissenschaften Lettlands.)PADIJ, N. N., SPEKTOR, M. R.: Anwendung von DDT zur Bekämpfung von Schädlingen in Baumstämmen. VI, 84.KOLOMIJEZ, N. G.: Neue Angaben über die Parasiten des sibirischen Spinners. VII, 57.SCHAPOVALOV, A. A.: Der groβe Pappelglasschwärmer — ein gefährlicher Schädling. VIII, 46.KOROVINA, N. J.: Wanzen als Samenschädlinge. VIII, 54. (Aus dem landwirtschaftlichen Institut in Woronesch.)OKUNEV, P. P.: Ein Verfahren zur schnellen Feststellung der Parasitierung von Insekteneiern. I, 59. (Aus dem forstlichen Forschungsinstitut in Leningrad.)
Über das Auftreten von Individualunterschieden beim Ringelspinner, Malacosoma neustria (L.)
Authors: Laux W. , Franz J. M. 
Published: July 2010

SummaryLarvae of Malacosoma neustria (L.) were examined as regards their behaviour towards light stimuli. As a result, two forms could be distinguished which behaved differently in a light gradient.The development of the larvae at different temperatures showed that the two larval types had different temperature ranges.Hungry larvae of the two forms showed different activity and endurance in searching for food.The two forms differed in their susceptibility to infection with Bacillus thuringensis Berliner showing a mortality of 73% in one case against 33% in the other.From the results it appears desirable to pay more attention in the future to qualitative differences in the individuals of a species.
Keys to Mite Species Found on Field Crops in Alexandria Region, U.A.R.
Authors: Abdel‐Shaheed G. A. , Hammad S. M. , El‐Sawaf S. K. 
Published: July 2010

AbstractThe present study covers fourty‐three species of mites, which fall into three suborders of the Acarina. These suborders are, the Parasitiformes, the Trombidiformes and the Sarcoptiformes, which are represented by seven, twenty six and ten species respectively. The system used in the classification of these species is modified from the works of Berlese (1882), Reuter (1909), Oudemans (1902, 1906) and others.Keys to the Suborders, Divisions, Supercohorts, Cohorts, Superfamilies, Families, Subfamilies, Tribes, Genera and Species, to which these fourty‐three species belong, are indicated.Zusammenfassungüber die an landwirtschaftlichen Kulturpflanzen in Alexandria lebenden MilbenartenAn landwirtschaftlichen Kulturpflanzen in der Region Alexandria wurden 43 Milbenarten gefunden, die zu 3 Unterordnungen gehören: Parasitiformes (7 Arten), Trombidiformes (26 Arten) und Sarcoptiformes (10 Arten). Zur Klassifizierung wurden vor allem die Systeme von Berlese (1882), Reuter (1909) sowie Oudemans (1902, 1906) verwendet.Es werden Bestimmungsschlüssel für die Unterordnungen, Divisionen, überkohorten, Kohorten, überfamilien, Familien, Unterfamilien, Triben, Gattungen und Arten aufgestellt.
Susceptibility of oat seedlings to oviposition by the frit fly, Oscinella frit L. (Dipt., Chloropidae)
Authors: Jonasson Th. 
Published: July 2010

AbstractThe susceptibility to oviposition by Oscinella frit in 16 oat cultivars was experimentally analysed in field and laboratory studies. The pattern of coleoptile withering and the corresponding separation of the coleoptile from the plant base was found to be of vital importance to the rate of oviposition. The oat seedlings were maximally attractive to the ovipositing females during the early stage of coleoptile disconnection, when the eggs could be conveniently deposited in the narrow crevice between the plant base and the coleoptile. The probability of a certain cultivar being utilized for egg‐laying was approximately proportional to the duration of a suitable coleoptile crevice. Oat cultivars with thin‐walled and rapidly withering coleoptiles were more liable to escape frit fly attack than were cultivars with thick‐walled and persistent coleoptiles. A high density of trichomes on the plant base surface did not entail any significant deterrent effect on egg‐laying frit fly females.ZusammenfassungZur Empfindlichkeit von Haferkeimlingen auf die Eiablage der Fritfliege, Oscinella frit L. (Dipt., Chloropidae)Im Freiland und Gewächshaus wurde die Empfindlichkeit von 16 verschiedenen Hafersorten gegenüber der Eiablage der Fritfliege untersucht. Es zeigte sich, daß das Absterben der Koleoptile und die damit verbundene Hohlraumbildung zwischen Koleoptile und Stengelgrund von entscheidender Bedeutung für die Eilegerate war. Die Haferkeimlinge waren für die eierablegenden Weibchen während des 1. Stadiums des Koleoptilenabsterbens am attraktivsten. In diesem Stadium war es leicht für die legebereiten Fliegen, die Legeröhre zwischen die Koleoptile und den Stengelgrund einzupressen. Die Anfälligkeit einer bestimmten Sorte zur Fritfliegen‐Eiablage war ungefähr proportional der Dauer des Koleoptilenabsterbens. Haferpflanzen mit dünneren und schneller absterbenden Koleoptilen waren für den Fritfliegenbefall weniger geeignet als solche mit dickeren und langsamer absterbenden Koleoptilen. Eine hohe Dichte von Haaren der Halmoberfläche hatte keine merkbare abweisende Wirkung auf eierablegende Fritfliegen.
Chemische Charakteristik des Kiefernharzes (Pinus spp.)1
Authors: Sturm U. , Francke W. , Mittak W. L. , Vité J. P. 
Published: July 2010

AbstractChemical characteristics of pine resin (Pinus spp.)Extensive knowledge of the chemical composition of pine resins may contribute to the resolution of chemotaxonomic problems as well as to a better understanding of significant insect/plant relationships.According to the presence or absence of n‐alkanes among the volatile constituents, pine resins may be devided into two main groups. Within each group a sufficient characterisation solely based on qualitative and/or quantitative variations in the pattern of monoterpenes is limited to certain exceptions only. In contrast, significant differences are found among the broad spectrum of sesquiterpene hydrocarbons even in morphologically closely related species. Patterns of low boiling compounds in the resins of P. monophylla and P. maximinoi are compared. Both species may be easily distinguished by characteristic differences in sesquiterpene distributions. Another important class of compounds which is suitable for chemotaxonomic approaches is represented by the tricyclic diterpenes of the abietan‐ and pimaran type. Distributions of diterpenes of P. maximinoi and P. pseudostrobus are compared and discussed.ZusammenfassungGründliche Kenntnis der chemischen Zusammensetzung von Kiefernharzen kann sowohl zur Lösung chemotaxonomischer Probleme beitragen als auch dem Verständnis von Insekten‐Wirtsbeziehungen dienen.In Abhängigkeit von der Anwesenheit leichtflüchtiger n‐Alkane können die Kiefernharze in zwei Hauptgruppen eingeteilt werden. Innerhalb dieser Gruppen ist eine Charakterisierung allein auf der Basis qualitativer und/oder quantitativer Unterschiede im Bereich der Monoterpene auf seltene Ausnahmen beschränkt. Im Gegensatz dazu finden sich auch bei morphologisch nahe verwandten Arten häufig charakteristische Unterschiede im Bereich der Sesquiterpenkohlenwasserstoffe. Die Terpenmuster von P. monophylla und P. maximinoi unterscheiden sich z. B. dadurch, daß das erstere sehr viel reichhaltiger an diesen Verbindungen ist und Copaen, Longifolen und γ‐Muurolen als Hauptkomponenten aufweist, während letzteres im Bereich der Sesquiterpene nur γ‐Amorphen als überragende Hauptkomponente enthält. Eine weitere Substanzklasse, die für chemotaxonomische Zwecke von Bedeutung ist, bilden die Diterpene vom Abietan‐ und Pimarantyp. Charakteristische Terpenmuster in diesem Bereich werden anhand der Beispiele von P. maximinoi und P. pseudostrobus diskutiert.
Subungual glomus tumour: magnetic resonance imaging findings
Authors: Koç O , Kivrak AS , Paksoy Y 
Published: July 2010

SUMMARYThe present study aims to present a case of a subungual glomus tumour with literature to the findings on magnetic resonance (MR) imaging. A 51‐year‐old man consulted his physician because of a pain in the nail bed of his thumb, which he had had for 2 years. A plain radiography and MR examination was performed. Physical examination showed a blue‐brown focus beneath the nail and there was deformation. A plain radiography demonstrated no abnormality. T1‐weighted spin‐echo images showed a well‐marginated, oval, slightly hyperintense lesion (4 mm diameter) located in the subungual region. On turbo spin‐echo T2‐weighted images the lesion was hyperintense with a hypointense rim. T1‐weighted spin‐echo images after intravenous administration of contrast medium showed strong enhancement. The lesion was completely excised at surgery and the diagnosis of a glomus tumour was established histologically. In conclusion, MR imaging offers excellent diagnostic information about a clinically suspected glomus tumour.
Serum visfatin is correlated with disease severity and metabolic syndrome in chronic hepatitis C infection
Authors: Huang Jee‐Fu , Huang Chung‐Feng , Yu Ming‐Lung , Dai Chia‐Yen , Huang Ching‐I , Yeh Ming‐Lun , Hsieh Meng‐Hsuan , Yang Jeng‐Fu , Hsieh Ming‐Yen , Lin Zu‐Yau , Chen Shinn‐Chern , Chuang Wan‐Long 
Published: July 2010

AbstractBackground and Aim:  Cytokines activation is a common feature in chronic hepatitis C (CHC) infection. Visfatin, as a recently‐recognized adipocytokine, may correlate with metabolic abnormalities. We aimed to elucidate the characteristics of visfatin in CHC patients.Methods:  This retrospective study included 102 treatment‐naïve CHC patients and 97 sex‐/age‐matched healthy adults. Serum visfatin levels were examined by an enzyme linked immunosorbent assay test. The correlation between visfatin and hepatitis C virus (HCV) infection in terms of virological, metabolic, and histopathological profiles was analyzed. The impact of visfatin on the treatment response to pegylated interferon plus ribavirin (PEGIFN/RBV) therapy was also assessed.Results:  The visfatin level was correlated significantly with fibrosis scores (r = 0.23, P = 0.02) in CHC patients. A significant higher visfatin level was observed in CHC patients with histological activity index scores of mild and more (P = 0.01) and advanced fibrosis (P = 0.04). The mean visfatin level (0.81 ± 0.28 log ng/mL) of 26 CHC patients with metabolic syndrome was significantly lower than their counterparts (0.95 ± 0.30 log ng/mL) (P = 0.03). There was no significant correlation between visfatin and HCV genotypes, viral load, and treatment response to PEGIFN/RBV therapy. Multiple logistic regression analyses demonstrated that metabolic syndrome was the leading negative variable (odds ratio = 0.09, 95% confidence interval = 0.02–0.46, P = 0.004) associated with high visfatin level, followed by advanced fibrosis (odds ratio = 2.88, 95% confidence interval = 1.06–6.78, P = 0.03).Conclusions:  Serum visfatin was correlated with disease severity and metabolic syndrome in CHC patients.
MDM2 antagonist can inhibit tumor growth in hepatocellular carcinoma with different types of p53 in vitro
Authors: Wang Jiabei , Zheng Tongsen , Chen Xi , Song Xuan , Meng Xianzhi , Bhatta Nishant , Pan Shangha , Jiang Hongchi , Liu Lianxin 
Published: July 2010

AbstractBackground and Aims:  Nutlin‐3, a selective small‐molecule inhibitor of the p53‐MDM2 interaction, has been shown to have antitumor activities in various tumors with wild‐type p53. However, its effect on hepatocellular carcinoma (HCC) with different types of p53 remains unclear. This study is designed to determine nutlin‐3′s antitumor efficacy and underlying mechanisms of action in human HCC cells.Methods:  Cell viability assay, cell cycle analysis, apoptosis assay, western blot, co‐ immunoprecipitation and siRNA experiments were analyzed in three human HCC cells. Anti‐tumoral effects of nutlin‐3 targeting the p53 and p73 pathways were evaluated in HCC cell lines.Results:  Nutlin‐3 exerted the greatest anti‐tumoral effect to three human HCC cells with wild‐type p53, mutant p53 and p53‐null. Nutlin‐3 not only upregulated p53 in HepG2 cells, but also p73 in Huh7 and Hep3B cells, and disrupted p53‐MDM2 and p73‐MDM2 complexes in HCC cells. The compound inhibited cell proliferation, induced G0/G1 phase arrest, decreased the levels of CyclinD1, CyclinE, CDK2, CDK4, PCNA and E2F‐1, and increased the levels of p21 and p27. It also induced apoptosis, increased the Bax/Bcl‐2 ratio, then activated caspase‐9 and caspase‐3.Conclusions:  Nutlin‐3 has significant anticancer effects against human HCC cells, regardless of p53 status, indicating that it is a promising therapy for human hepatocellular carcinoma.
IVI epoprostenol as salvage therapy in pulmonary arterial hypertension: an Australian perspective
Authors: Salamonsen M. , Keating D. , Whitford H. , Bailey M. , Miller T. , Manterfield C. , Williams T. 
Published: July 2010

AbstractBackground:  IVI epoprostenol is the only therapy for pulmonary arterial hypertension (PAH) with a randomized controlled trial demonstrating improved survival, when used as first‐line monotherapy. In Australia it is used as salvage therapy for those failing treatment with other targeted therapies or presenting in World Health Organization functional class (FC) IV.Aims:  Report experience with IVI epoprostenol, administered as salvage therapy for the treatment of adults with PAH in a single Australian PAH centre.Methods:  Retrospective case series of all patients commenced on IVI epoprostenol for PAH, between 2002 and 2010. Review of case notes with collection of data at baseline and after treatment, including FC, 6‐min walk test (6MWT), right ventricular systolic pressure (RVSP) on echocardiogram, patient survival and treatment complications. Change in indices was assessed using the Wilcoxon Sign Rank Test and is expressed as median (inter‐quartile range).Results:  A total of 23 patients was included. Treatment was generally well tolerated with few major complications. At the end of the study period, nine patients were successfully bridged to transplant, five had a sustained response to IVI epoprostenol, six had an incomplete response but were clinically stabilized, two died awaiting transplant and one died who was not a candidate for transplantation. Overall, when measured at best level post initiation of IVI epoprostenol, there were significant improvements in FC −1 [0 to −1] (P < 0.0001), 6MWT (m) +117 [70–264] (P= 0.002) and RVSP (mmHg) −7.0 [4.0 to −45] (P= 0.03).Conclusion:  Findings support efficacy of epoprostenol as salvage therapy for patients with PAH.
Qualitative Research in Management: A Decade of Progress
Authors: Bluhm Dustin J. , Harman Wendy , Lee Thomas W. , Mitchell Terence R. 
Published: July 2010

abstractApproximately 10 years ago, Lee et al. reviewed the qualitative methods published during 1979–99 in the major US journals in the organizational sciences. This ten‐year follow‐up review of 198 qualitative articles assesses the progress made in qualitative research in management by specifically considering: (1) the strength and legitimacy of recent publications that challenge any positivistic stigmatizations of qualitative research; (2) the methodological advances in qualitative methods, including the use and elucidation of novel techniques; and (3) the general contribution of qualitative research to the accumulation of management knowledge. By encompassing both US and European journals in our review, we also compare and contrast the qualitative research published on both sides of the Atlantic, stressing what each can learn from the other. We highlight exemplary articles and procedures and make recommendations for the next decade of qualitative research in management.
d‐glufosinate as a male sterility agent for hybrid seed production
Authors: Hawkes Tim , Pline‐Srnic Wendy , Dale Richard , Friend Emma , Hollinshead Tricia , Howe Peter , Thompson Paul , Viner Russell , Greenland Andy 
Published: July 2010

SummaryA chemical male sterility system based on anther‐localized conversion of the inactive d‐enantiomer of the herbicide, glufosinate (2‐amino‐4‐(methylphosphinyl)‐butanoate) to the phytotoxic l is described. Highly pure d‐glufosinate was isolated in >98% enantiomeric excess from the racemate via fermentation with a strain of Escherichia coli expressing the PAT (l‐glufosinate N‐acetyl transferase) gene and purification of the unreacted d‐enantiomer from the broth by ion exchange. A modified (F58K, M213S) form of the d‐amino acid oxidase (DAAO) (EC 1.4.3.3) from Rhodosporidium toruloides was designed, tested in vitro and found to efficiently oxidize d‐glufosinate to its 2‐oxo derivative [2‐oxo‐4‐(methylphosphinyl)‐butanoic acid]. Tobacco (Nicotiana tabacum) plants were transformed to express this modified oxidase under control of the TAP1 tapetum‐specific promoter. A number of the resultant transgenic lines exhibited complete male sterility that persisted for two or more weeks immediately following foliar treatment with 75 or 200 g/ha of d‐glufosinate without exhibiting obvious phytotoxic symptoms or any measurable decline in female fertility. Similarly, plants containing the same construct and, additionally, a PAT gene expressed from a plastocyanin promoter exhibited significantly reduced male fertility and no reduction in female fertility following foliar application of racemic glufosinate. Thus, foliar application of d‐glufosinate either purified or as the commercial herbicide, combined with anther expression of a modified DAAO promises to provide a cost‐effective conditional chemical male sterility system with the characteristics necessary for practical F1 hybrid seed production.
Interferon and lamivudine vs. interferon for hepatitis B e antigen‐positive hepatitis B treatment: meta‐analysis of randomized controlled trials
Authors: Rudin Dan , Shah Sooraj M. , Kiss Alexander , Wetz Robert V. , Sottile Vincent M. 
Published: July 2010

AbstractAims: To compare interferon monotherapy with its combination with lamivudine for hepatitis B e antigen (HBeAg)‐positive hepatitis B treatment.Methods: Two independent researchers identified pertinent randomized controlled trials. The trials were evaluated for methodological quality and heterogeneity. Rates of sustained virological and biochemical responses, and HBeAg clearance and seroconversion were used as primary efficacy measures. Quantitative meta‐analyses were conducted to assess differences between groups for conventional and pegylated interferon, and overall.Results: Greater sustained virological, biochemical and seroconversion rates were observed with addition of lamivudine to conventional [odds ratio (OR)=3.1, 95% confidence intervals (CI) (1.7–5.5), P<0.0001, OR=1.8, 95% CI (1.2–2.7), P=0.007 and OR=1.8, 95% CI (1.1–2.8), P=0.01 respectively], although not pegylated [OR=1.1, 95% CI (0.5–2.3), P=0.8, OR=1.0, 95% CI (0.7–1.3), P=0.94, and OR=0.9, 95% CI (0.6–1.2), P=0.34 respectively] interferon‐α, with no significant affect on HBeAg clearance rates [OR=1.6, 95% CI (0.9–2.7), P=0.09, and OR=0.8, 95% CI (0.6–1.1), P=0.26 respectively]. Excluding virological response (P<0.001), pegylated interferon monotherapy and conventional interferon and lamivudine combination therapy were similarly efficacious (P>0.05), with the former studied in harder to treat patients, as evidenced by the superior virological response observed with conventional as compared with pegylated interferon monotherapy (P<0.0001).Conclusion: In comparable populations, pegylated interferon monotherapy is likely to be equally or more efficacious than conventional interferon and lamivudine combination therapy, thus constituting the treatment of choice, with no added benefit with lamivudine addition. However, when conventional interferon is used, its combination with lamivudine should be considered.