bluuebunny/crossref_metadata_2025_split huggingface dataset:
Causes of Stillbirth: An Analysis of 77 Cases
Authors: Yamauchi Ariko , Minakami Hisanori , Ohkuchi Akihide , Usui Rie , Idei Sadayoshi , Sato Ikuo 
Published: May 2010

AbstractObjective: To devise preventive measures for stillbirths, which account for more than 70% of perinatal deaths in Japan.Methods: We retrospectively reviewed the medical records of 77 women with singleton pregnancies who gave birth to stillborn infants at ≥ 30 weeks between 1979 and 1996 at our hospital.Results: Major malformations were present in 21 (27%) of 77 infants, including 11 infants with anencephaly. Two infants (2.6%) were severely hydropic. Preeclampsia preceded the stillbirth and might have been an indirect cause of stillbirth in 21 (39%) of 54 women whose infants had normal formations. The cause of stillbirth in 33 non‐preeclamptic women was unclear in 15 (28%), abruptio placentae in 9, fetal growth retardation in 3, the HELLP syndrome in 3, chorioamnionitis in 2, and cord accident in 1. Abruptio placentae also occurred in 9 of 21 preeclamptic patients. Thus, abruptio placentae was responsible for 18 (33%) of 54 stillborn infants with a grossly normal appearance. An autopsy was performed on only 13 (24%) of 54 infants with grossly normal appearance and did not provide new information relating to deaths.Conclusions: The causes of stillbirth were many and varied, with a large proportion having no obvious cause, although autopsies were underused. Increased monitoring for women with preeclampsia and early diagnosis and prompt delivery for women with abruptio placentae might be helpful in reducing the number of stillbirths.
Intrapartum Common Peroneal Nerve Compression Resulted in Foot Drop: A Case Report
Authors: Qublan Hussein S. T. , Al‐Sayegh Hisham 
Published: May 2010

AbstractThis case report is to illustrate a case of a 24‐year‐old Jordanian woman, gravida 1, para 0 who developed intrapartum foot drop due to compression injury of the common peroneal nerve behind the head of fibula. Diagnosis was based on history, clinical examination and electrophysiological studies. Treatment included daily sessions of physiotherapy. Complete recovery of the condition took place within 2 months.
Asymptomatic Uterine Incarceration at Term Gestation: A Case Report
Authors: Li Yiu‐Tai , Tsui Man‐Shing , Yin Chang‐Sheng , Lin Hsien‐Ming , Chan Chying‐Chyuan 
Published: May 2010

AbstractUterine incarceration is a rare event complicating pregnancy. Herein, we present a unique case of an asymptomatic term pregnancy with uterine incarceration; this patient had had an anterior myomectomy 3 years earlier. She had an asymptomatic antenatal course and incidental identification of uterine incarceration during cesarean section. We also address the importance of early recognition and appropriate management regarding this circumstance.
Spinal Cord Compression: A Rareness in Pregnant Thalassemic Woman
Authors: Phupong Vorapong , Uerpairojkij Boonchai , Limpongsanurak Sompop 
Published: May 2010

AbstractThalassemia is a common hematological disease in Southeast Asia. Extramedullary hematopoiesis is common sequelae in thalassemic patients but extramedullary hematopoiesis in the spinal epidural space that leads to paraparesis in pregnancy is very rare. We managed a thalassemic patient with extramedullary hematopoiesis and spinal cord compression during pregnancy. The diagnosis was made on clinical features and magnetic resonance imaging (MRI) showing a paravertebral mass infiltrating the epidural space. She was treated successfully with repeated blood transfusions until delivery. Fetal growth restriction was found but otherwise the fetus was clinically normal. She had an uneventful recovery when she was seen 6 weeks after delivery.
Vaginal Misoprostol in Termination of Second Trimester Pregnancy
Authors: Herabutya Yongyoth , Chanrachakul Boonsri , Punyavachira Piyaporn 
Published: May 2010

AbstractObjective: To study the effectiveness and complications of 600 μg of intravaginal misoprostol for terminating second trimester pregnancies.Study Design: One hundred and seventy‐two patients undergoing termination of pregnancy between March 1997 and April 1999 were studied. Each patient received 600 μg of intravaginal misoprostol every 12 hours until abortion occurred.Results: The mean induction to abortion time was 24.1 ± 21.6 hours. The percentage of women aborting within 24 and 48 hours was 68.6 and 89.5 respectively. There was no significant difference in the mean induction to abortion time and the percentage of women aborted within 48 hours between nulliparous and multiparous women. The mean amount of misoprostol used was 1405.5 ± 1084.6 μg. Incomplete abortion occurred in 23.3% of women. The most common complication was temperature of more than 38° occurred in 41% followed by diarrhoea (20%), nausea and vomiting (15%).Conclusion: Six hundred μg of vaginal misoprostol is effective, but whether the 48 hours abortion rate can be improved with a large dose or shortened the time interval between doses, requires further study.
Peritoneal and Peripheral B‐1‐Cell Populations in Patients with Endometriosis
Authors: Chishima Fumihisa , Hayakawa Satoshi , Hirata Yoshiyasu , Nagai Nobuhisa , Kanaeda Takashi , Tsubata Katsuo , Satoh Kazuo 
Published: May 2010

AbstractObjective: The purpose of this study was to investigate the frequency of B‐1 cells in the peritoneal cavity and peripheral blood of patients with endometriosis.Materials and Methods: We examined 31 patients with endometriosis and 14 normal nonpregnant women. Peripheral blood cells and peritoneal exudate cells (PECs) were stained with FITC or PE‐labeled anti‐CD5/CD19 monoclonal antibodies. Immunofluorescence analysis was performed using a flow cytometer. The significance of differences between the patient and control groups was determined by the non‐parametric Mann‐Whitney test.Results: There was no significant difference in the percentages of B‐1 cells in the peripheral blood of women with and without endometriosis (median, 22.7%; range, 4.7–92.3% vs median, 20.05%; range, 11.1–12.6%, respectively). Endometriosis patients with antinuclear antibodies (ANAs) demonstrated significantly elevated B‐1 cells compared to both endometriosis patients without ANAs and normal controls (p < 0.005 and p < 0.05, respectively). Endometriosis patients demonstrated significantly higher B‐1 cell populations (B‐1 cells/total B‐cell ratio) in PECs than did non‐endometriosis patients (p < 0.05).Conclusions: The peripheral B‐1‐cell population in patients with endometriosis is related to ANA production. B‐1 cells might play important roles in the development of endometriosis through autoantibody production.
A Case Report: Verrucous Carcinoma of the Endometrium — The Difficulty of Diagnosis, and a Review of the Literature
Authors: Shidara Yoshihiro , Karube Akihiro , Watanabe Masato , Satou Eiju , Uesaka Yoshinori , Matsuura Tooru , Tanaka Toshinobu 
Published: May 2010

AbstractA verrucous carcinoma is a subtype of well‐differentiated squamous‐cell carcinomas, arising in the vagina, vulva, and uterine cervix. But a verrucous carcinoma very rarely arises in the uterine endometrium. The present paper presents a case of a verrucous carcinoma of the endometrium that is described in association with the tumor marker SCC; this paper also includes a review of the relevant literature.
Prevalence of Human Papillomavirus Infection and Its Correlation with Cervical Lesions in Commercial‐Sex Workers in Japan
Authors: Ishi Kazuhisa , Suzuki Fujihiko , Saito Akira , Kubota Takeyoshi 
Published: May 2010

AbstractObjective: To investigate the prevalence of the human papillomavirus (HPV) infection and its correlation with cervical lesions in commercial‐sex workers (CSWs) who attended a sexually transmitted disease (STD) clinic in an entertainment area in Tokyo.Methods: Surveys were conducted on 546 prostitutes and 233 control subjects. In all subjects, HPV detection was performed by the hybrid capture method. A cervical cytological examination was performed on 247 prostitutes and 233 control subjects.Results: The HPV‐positive rates in the two periods of study were higher (p < 0.01) in CSWs than in the control subjects. When the cytological grades were examined according to HPV‐positive rates, the proportion of cytologic Class IIIa to Class IV was significantly higher (p < 0.01) in the HPV‐positive CSWs than in the HPV‐negative CSWs or in the normal subjects.Conclusion: The high frequencies of HPV infection and cervical dysplasia in the CSWs in the present series might predict a higher risk of cervical cancer in this group of subjects.
Epidural Analgesia in Primigravidae in Spontaneous Labour at Term: A Prospective Study
Authors: Leong Eugene W. K. , Sivanesaratnam V. , Oh Lilian L. L. , Chan Y. K. 
Published: May 2010

AbstractObjectives: To prospectively study the intervention rate, duration of labour, malpositions, fetal outcome, maternal satisfaction, voiding complications and adverse events in healthy primigravidae in spontaneous labour at term following epidural analgesia.Methods: A prospective randomized study involving 55 patients in the epidural group and 68 in the control pethidine — inhalational entonox group.Results: There were significantly more obstetric interventions (instrumental deliveries) in the epidural group (p < 0.01). The total duration of labour and the duration of the second stage was prolonged in the epidural group (p < 0.01). There were more malpositions at the second stage of labour in the epidural group (p < 0.02). There were no differences in fetal outcome (Apgar scores and Special Care Nursery admissions). Patients in the epidural group were consistently happier with their method of pain relief (p < 0.01). Two patients required blood patches while another 2 patients had persistent backache post epidural analgesia.Conclusion: Epidural analgesia in primigravidae in spontaneous labour at term led to an increased instrumental delivery rate, prolonged duration of labour, greater rate of malpositions in the second stage, increased oxytocin requirements but with no difference in fetal outcomes but with happier mothers as compared to the control group.
A Prospective Randomized Study Comparing Endocrinological and Clinical Effects of Two Types of GnRH Agonists in Cases of Uterine Leiomyomas or Endometriosis
Authors: Takeuchi Hiroyuki , Kobori Hiroyuki , Kikuchi Iwao , Sato Yuichi , Mitsuhashi Naoki 
Published: May 2010

AbstractObjective:In order to assess the endocrinological changes associated with 2 types of low‐dose GnRH agonists depot as well as their clinical efficacy, we performed a randomized prospective comparison study of patients having uterine leiomyomas or endometriosis.Methods:A prospective randomized study involving 67 patients with uterine leiomyomas or endometriosis was carried out. These patients were randomly administered either buserelin MP 1.8 mg (Group B,n= 34) or leuprolide 1.88 mg (Group L,n= 33). In each group we evaluated the symptoms of genital bleeding and hot flashes during GnRHa treatment, as well as the levels of serum LH, FSH, and estradiol 8 weeks after the start of treatment. In addition, the endometrial thickness was measured by transvaginal ultrasonography, and changes in the volume of the uterine leiomyoma or endometrial cyst at the end of treatment. The GnRHa depot was administered from 3 to 8 times, 28 days apart, in both groups.Results:The incidence of menstruation‐like genital bleeding 8 weeks after treatment was significantly (p < 0.01) higher in Group B. However this difference disappeared by 12 weeks after treatment. The climacteric symptom of hot flashes was found to be significantly (p < 0.01) more severe in Group L, and this tendency continued until 20 weeks after treatment. The 2 groups did not differ significantly with regard to the levels of the serum LH, FSH, and estradiol at 8 weeks after treatment or in the endometrial thickness at the end of the GnRHa treatment. In both groups, the volumes of the uterine leiomyomas were significantly (p < 0.01) lower after the treatment. In contrast, the volumes of the endometrial cysts did not decrease after administration of GnRHa in both groups.Conclusion:Leuprolide 1.88 induced pituitary down regulation more rapidly than buserelin MP. However the hypoestrogenic symptoms such as hot flashes were more severe in cases treated with leuprolide 1.88 than in those treated with buserelin MP. Our data confirm that the therapeutic efficacy of buserelin MP and leuprolide 1.88 are similar, with both being sufficient to treat uterine leiomyomas and endometriosis.
Maternal Mortality Associated with Eclampsia and Severe Preeclampsia of Pregnancy
Authors: Sawhney H. , Aggarwal N. , Biswas R. , Vasishta K. , Gopalan S. 
Published: May 2010

AbstractObjective: To analyse factors associated with maternal mortality in eclampsia and preeclampsia.Method: Retrospective analysis of 69 maternal deaths due to (eclampsia‐61; severe preeclampsia‐8) was carried out during a period of 17 years (1982–1998). Maternal condition on admission, associated complications and principal cause of death was analysed in each case.Results: Mean time interval between hospitalization and maternal death was 49.56 + 62.01 hrs (1–240 hrs). Twenty (28.9%) women died undelivered. Twenty‐three (37.7%) women were in grade IV coma and 52.4% of eclampsia patients had recurrent convulsions (> 10) prior to admission. Associated complications in form of hemorrhage, cerebrovascular accidents, acute renal failure, jaundice, aspiration pneumonia and pulmonary oedema were 30.4, 31.8, 34.8, 18.8, 17.8, and 5.8%, respectively. Maternal mortality in eclampsia was significantly low in time period B (4.1%) when magnesium sulphate was used as an anticonvulsant.Conclusions: Maternal condition on admission and associated complications are the major determinant of maternal outcome. Use of magnesium sulphate is associated with significant reduction of maternal mortality.
Antioxidant Nutrients and Lipid Peroxide Levels in Thai Preeclamptic Pregnant Women
Authors: Panburana Panyu , Phuapradit Winit , Puchaiwatananon Orawan 
Published: May 2010

AbstractObjective: To compare the antioxidant nutrients and lipid peroxide levels in preeclampsia and normal pregnant women.Methods: Antioxidant nutrients (vitamin A and E) were measured by high‐pressure liquid chromatography, vitamin C was measured by the dinitrophenyl hydrazine method, lipid peroxides were measured by the malondialdehyde method in 20 severe preeclampsia, 30 mild preeclampsia and 60 normal pregnant women as controls.Results: Vitamin C levels in severe and mild preeclampsia were significantly less than those in control group. The corrected vitamin E and vitamin A levels were significantly decreased only in severe preeclampsia. While the lipid peroxide levels in both mild and severe preeclampsia were significantly increased when compared with the nomal pregnancy.Conclusions: Preeclampsia is associated with the imbalance between lipid peroxides and antioxidant nutrients (vitamin C and E). The imbalances favour lipid peroxides with the increasing severity of preeclampsia.
A Case of a Primary Ovarian Leiomyosarcoma
Authors: Inoue Jun , Gomibuchi Hideto , Minoura Shigeki 
Published: May 2010

AbstractA primary ovarian leiomyosarcoma is extremely rare. Moreover, there is no established treatment modality other than surgery, and the prognosis is extremely poor. We report a case of a primary ovarian leiomyosarcoma.The patient was a gravida 4, para 2, 73‐year‐old female. She first presented with chief complaints of constipation and a pelvic mass. A physical examination revealed a solid tumor in the pelvic cavity. Which was about the size of an infant's head and had an irregular shape. The patient was suspected of having a subserosal myoma of the uterus or an ovarian tumor, and she was subjected to a laparotomy. A solid tumor about the size of an infant's head was found in the left uterine adnexa, and an intraoperative rapid pathological diagnosis of an ovarian leiomyosarcoma was made. A total abdominal hysterectomy, a bilateral salpingo‐oophorec‐tomy, a pelvic lymphadenectomy, and an omentectomy were then performed. The final pathological diagnosis confirmed a left primary ovarian leiomyosarcoma. After a series of discussions with the patient's family about her therapeutic plan, we decided to let the patient be followed‐up without adjuvant therapy.Forty‐two months after the surgery, the patient accumulated massive amounts of pleural effusion and ascites, with extensive organ metastasis. She received terminal care and soon died.
Misoprostol in Labor Induction
Authors: Ozan Hakan , Uncu Gürkan , Yildirim Volkan , Omak Melike , Kara Havva Filiz , Tüfekci Mehpare 
Published: May 2010

AbstractThe efficacy of a new dosing regimen of misoprostol, a recently introduced labor‐inducing agent, was studied.Fifty‐eight patients received 50 μg of misoprostol intravaginally and the dose was repeated every 3 hours until uterine contractions begin. Those who had an adequate contraction pattern, defined as three contractions in 10 minutes, were not given the repeat dose. Oxytocin augmentation, but not further misoprostol doses, was used in patients with an inadequate contraction pattern. The maximum total daily dose was 200 μg.The patients had the mean age of 28.9 + 5.4, the mean gestational age of 211.8 + 46.6 days, the mean gravidity of 2.5 + 1.2, the mean parity of 0.9 + 0.9 and the mean initial Bishop score of 1.6 + 1.8. The mean required dose of misoprostol was 120.5 + 54.7 μg and 10 of 58 patients required oxytocin augmentation. The mean induction of labor to delivery time was 701.5 + 404.0 minutes. When 3 cases who gave birth with caesarean section were excluded, the interval was 708.4 + 407.2 minutes. The mean 5th minute Apgar score of the newborns was 8.2 + 2.5.Two patients developed tachysystole after the second dose of misoprostol and were managed with vaginal irrigation and O2 supplementation successfully. Slight nausea and vomiting in 2 patients were the other adverse reactions.Our findings revealed that, 50 μg intravaginal misoprostol, combined with oxytocin augmentation when necessary, appears to be an effective and safe method of labor induction.
Intracranial Venous Thrombosis Associated with Severe Antithrombin‐III Deficiency in Pregnancy
Authors: Özsener Serdar , Terek Mustafa Cosan , Saydam Güray , Celebisoy Nese , Öztekin Kemal , Özkinay Erdinc 
Published: May 2010

AbstractWe report a patient with intracranial venous thrombosis in the third trimester of pregnancy associated with severe antithrombin‐III deficiency. The evaluation of protein C, protein S and antithrombin‐III levels in patients with thrombotic events during pregnancy may reveal the specific cause of the thrombotic event and thereby influence patient management
Second Trimester Pregnancy Termination: A Comparison of 600 and 800 Micrograms of Intravaginal Misoprostol
Authors: Herabutya Yongyoth , Chanrachakul Boonsri , Punyavachira Piyaporn 
Published: May 2010

AbstractObjective: To compare the effectiveness of 600 and 800 μg of misoprostol administered intravaginally every 12 hours for termination of second trimester pregnancies.Methods: One hundred and forty‐three pregnant women at 14–26 weeks' gestation were randomized in 2 groups to receive either 600 μg (N = 67), or 800 μg (N = 76) of intravaginal misoprostol every 12 hours until abortion was induced.Results: The incidences of abortion within 24 hours after initial drug administration were 82.1% (n = 55) and 78.9% (n = 60), within 48 hours 92.5% (n = 62) and 92.1% (n = 70), the mean abortion intervals were 15.2 (10.5, 20.8) hours and 15.3 (10.2, 21.8) hours, the complete abortion rates 77.6% (n = 52) and 72.4% (n = 55), and body temperature of more than 38°C were 26.9% (n = 18) and 71.1% (n = 54, p = < 0.001) in the 600 and 800 μg group, respectively. All other side‐effects were similar between the 2 groups.Conclusion: In consideration of effectiveness and febrile complication, we suggest that 600 μg applied every 12 hours is the most appropriate dose to use for second trimester termination
Indomethacin Therapy in the Treatment of Polyhydramnios Due to Placental Chorioangioma
Authors: Kriplani Alka , Abbi Monica , Banerjee Neelam , Roy Kallol K. , Takkar D. 
Published: May 2010

AbstractA 26‐year‐old primigravida presented with acute polyhydramnios at 30 weeks gestation. Ultrasonography revealed a large placental chorioangioma with severe hydramnios. No anomalies were detected in the fetus. Preterm labor started with respiratory distress and indomethacin, 25 mg was given every 6 hours. The patient showed a good response with improvement of the hydramnios and respiratory symptoms. A normal infant with no neonatal complications was delivered 3 weeks later.
Sonographic Fetal Weight Estimation in a South‐East Asian Population
Authors: Venkat Annapoorna , Chinnaiya Anandakumar , Gopal Malarvishy , Mongelli Joe Max 
Published: May 2010

AbstractObjectives: To determine the optimal sonographic fetal weight estimation formula for a mixed south‐east Asian population near term.Methods: Seventy‐eight uncomplicated pregnancies were monitored between January 1996 and January 1997. Biparietal diameter, head circumference, abdominal circumference and femur length were measured and the following formulae were tested: Campbell, Shepherds and Hadlock. The estimated fetal weight was calculated by 12 different methods. The weight estimate was then projected forward to the time of delivery using the gestation‐adjusted forward projection method. The weight estimation error was derived from the difference between the projected fetal weight and birth weight, and expressed as a percentage of birth weight.Results: The mean time interval from the time of ultrasound fetal weight estimation to delivery was 4.4 days. The birth weight ranged between 2,330 to 4,215 g. The best performing formula was Hadlock's formula using the head circumference, abdominal circumference and femur, with the perimeters calculated using the ellipse function. The standard deviation of error for this formula was 8.66%.Conclusion: Even though the Hadlock formula was originally derived from an American population, it was equally useful in south‐east Asian population.
A New Hysteroscopic Tubal Embryo Transfer Catheter: Development and Clinical Application
Authors: Kitamura Seiji , Sugiyama Takeshi , Iida Etsurou , Miyazaki Toyohiko , Yoshimura Yasunori 
Published: May 2010

AbstractObjective: Development and clinical application of a new hysteroscopic tubal embryo transfer catheter.Method: Catheterization was performed in 60 patients at hysteroscopic insemination into tube, using 3 French catheters, in which the distal 3,4, and 5 cm tapered to 2 French. Hysteroscopic tubal embryo transfer and conventional IVE‐ET were performed in 30 patients with normal tubes, who failed to achieve pregnancy after 2 IVF‐ET trials.Result: The success rate of complete insertion with the catheter tapering at the distal 3 cm was significantly higher than that at the distal 5 cm. Since we obtained the highest success rate of insertion with the catheter tapering at the distal 3 cm, we selected this catheter for the h‐TEST. The rate of pregnancy in h‐TEST was significantly higher than that in conventional ET.Conclusion: The h‐TEST using our catheter was useful for establishing pregnancy in assisted reproduction.
Lymphatic Filariasis of the Ovary and Mesosalpinx
Authors: Sethi Seema , Misra Kiran , Singh Usha Rani , Kumar Dilip 
Published: May 2010

AbstractWe report 2 cases of filariasis, one in the ovary and the other in the mesosalpinx. In the first case, the patient underwent panhystrectomy and in the second case, right ovarian cystectomy with right salpingectomy were performed under general anaesthesia. Histopathology showed adult filarial worms in the dilated lymphatics of the right ovary, in the first case and in the mesosalpinx, in the second case. Both patients presented with complaints related to gynecological problems and not filariasis. Reports of filariasis in the literature and possible treatments and prevention strategies are also discussed.