bluuebunny/crossref_metadata_2025_split huggingface dataset:
C-reactive protein, an early marker of community-acquired sepsis resolution: a multi-center prospective observational study
Authors: Póvoa Pedro , Teixeira-Pinto Armando M , Carneiro António H ,   the Portuguese Community-Acquired Sepsis Study Group (SACiUCI)
Published: July 2011

Abstract
Introduction
C-reactive protein (CRP) has been shown to be a valuable marker in the diagnosis of infection and in monitoring its response to antibiotics. Our objective was to evaluate serial CRP measurements after prescription of antibiotics to describe the clinical course of Community-Acquired Sepsis admitted to intensive care units (ICU).

Methods
During a 12-month period a multi-center, prospective, observational study was conducted, segregating adults with Community-Acquired Sepsis. Patients were followed-up during the first five ICU days, day of ICU discharge or death and hospital outcome. CRP-ratio was calculated in relation to Day 1 CRP concentration. Patients were classified according to the pattern of CRP-ratio response to antibiotics: fast response if Day 5 CRP-ratio was < 0.4, slow response if Day 5 CRP-ratio was between 0.4 and 0.8, and no response if Day 5 CRP-ratio was > 0.8. Comparison between survivors and non-survivors was performed.

Results
A total of 891 patients (age 60 ± 17 yrs, hospital mortality 38%) were studied. There were no significant differences between the CRP of survivors and non-survivors until Day 2 of antibiotic therapy. On the following three days, CRP of survivors was significantly lower (P < 0.001). After adjusting for the Simplified Acute Physiology Score II and severity of sepsis, the CRP course was significantly associated with mortality (ORCRP-ratio = 1.03, confidence interval 95%= (1.02, 1.04), P < 0.001). The hospital mortality of patients with fast response, slow response and no response patterns was 23%, 30% and 41%, respectively (P = 0.001). No responders had a significant increase on the odds of death (OR = 2.5, CI95% = (1.6, 4.0), P < 0.001) when compared with fast responders.

Conclusions
Daily CRP measurements after antibiotic prescription were useful as early as Day 3 in identification of Community-Acquired Sepsis patients with poor outcome. The rate of CRP decline during the first five ICU days was markedly associated with prognosis. The identification of the pattern of CRP-ratio response was useful in the recognition of the individual clinical course.
Harmonin (Ush1c) is required in zebrafish Müller glial cells for photoreceptor synaptic development and function
Authors: Phillips Jennifer B. , Blanco-Sanchez Bernardo , Lentz Jennifer J. , Tallafuss Alexandra , Khanobdee Kornnika , Sampath Srirangan , Jacobs Zachary G. , Han Philip F. , Mishra Monalisa , Titus Tom A. , Williams David S. , Keats Bronya J. , Washbourne Philip , Westerfield Monte 
Published: July 2011

SUMMARY
Usher syndrome is the most prevalent cause of hereditary deaf-blindness, characterized by congenital sensorineural hearing impairment and progressive photoreceptor degeneration beginning in childhood or adolescence. Diagnosis and management of this disease are complex, and the molecular changes underlying sensory cell impairment remain poorly understood. Here we characterize two zebrafish models for a severe form of Usher syndrome, Usher syndrome type 1C (USH1C): one model is a mutant with a newly identified ush1c nonsense mutation, and the other is a morpholino knockdown of ush1c. Both have defects in hearing, balance and visual function from the first week of life. Histological analyses reveal specific defects in sensory cell structure that are consistent with these behavioral phenotypes and could implicate Müller glia in the retinal pathology of Usher syndrome. This study shows that visual defects associated with loss of ush1c function in zebrafish can be detected from the onset of vision, and thus could be applicable to early diagnosis for USH1C patients.
Dual activity of serum lipoprotein-associated phospholipase A2 yielding positive and inverse associations with cardiometabolic risk
Authors: Onat Altan , Hergenç Gülay , Can Günay , Uğur Murat , Nartop Filiz 
Published: July 2011

Abstract

Background: The clinical relevance of serum lipoprotein-associated phospholipase A2 (Lp-PLA2) in populations prone to cardiometabolic risk needs exploration. We determined major covariates of Lp-PLA2 mass, and its associations with cardiometabolic disorders.

Methods: In 736 Turkish adults, serum total Lp-PLA2 mass was determined by immunoassay. Its association with cardiometabolic risk was assessed in three categories. In a second sample of 98 subjects, enzyme protein in high-density lipoprotein (HDL) was also assayed after precipitation.

Results: Significant inverse correlation existed with high triglyceride/low HDL cholesterol dyslipidemia, waist girth, apolipoprotein C-III, homeostatic model assessment, and linear inverse associations in women with lipoprotein (a) and fibrinogen, suggesting that Lp-PLA2 mass reflected insulin sensitivity and that HDL bound enzyme mass dominated the associations. Among men, positive linear association with total cholesterol suggested additional association with low-density lipoprotein (LDL)-bound enzyme. High (>450 ng/mL) opposed to low (<210 ng/mL) circulating Lp-PLA2 mass was associated with prevalent and incident coronary heart disease (CHD) in men. One SD increment in Lp-PLA2 was associated with a 1.64-fold (95% CI 1.00; 2.70) likelihood of CHD, after adjustment for potential confounders. Furthermore, Lp-PLA2 categories were significantly, independently and inversely associated in men with diabetes only (OR 0.61) and in women with metabolic syndrome only (OR 0.68), for a 1-SD increment.

Conclusions: Serum total Lp-PLA2 mass may indicate either elevated or diminished cardiometabolic risk, specific for gender, depending on its partitioning in lipoprotein groups.
WSO2 Stratos: An Application Stack to Support Cloud Computing
Authors: Azeez Afkham , Perera Srinath , Weerawarana Sanjiva , Fremantle Paul , Uthaiyashankar Selvaratnam , Abesinghe Samisa 
Published: July 2011

Abstract
Cloud computing has heralded many advantages including self-service, elasticity, pay as you go, improved accessibility to computation resources, and ease of deployment and deployment automation. However, to extend those advantages to a larger audience, higher-level abstractions such as Software as a Service (SaaS) or Platform as a Service (PaaS) are needed. This paper presents Stratos, which is a Platform-as-a-Service based around the principles and design of Service Oriented Architecture (SOA). Furthermore, we introduce the concept of Cloud Native attributes, which we argue are properties essential to extend the benefits of the underlying Cloud to PaaS and SaaS users. We present Stratos as a Cloud Native PaaS offering, discuss the architecture that enables Cloud Native attributes, and discuss scenarios where Stratos can be useful to the end user.
A Framework for Studying Cloud Value Systems
Authors: Leukel Jörg , Kirn Stefan 
Published: July 2011

Abstract
Cloud computing is about to change the way of delivering IT services to end users. Service providers are required to re-think both their value proposition and value creation processes. We present a framework for studying these cloud value systems. The framework is grounded on New Institutional Economics and provides means for describing, explaining, and designing cloud value systems.
Identifying and Mitigating Insider Threats
Authors: Probst Christian W. 
Published: July 2011

Abstract
Organisations face many threats that coarsely can be separated in inside threats and outside threats. Threats from insiders are especially hard to counter since insiders have special knowledge and privileges. Therefore, malicious insider actions are hard to distinguish from benign actions. After discussing new definitions of insiders and insider threats, this article gives an overview of how to mitigate insider threats and discusses conflicting goals when dealing with insider threats.
68.3: Achieving High Efficiency White Organic Light‐emitting Diodes based on Transient Electroluminescence Analysis
Authors: Lan Yi‐Hsin , Hsiao Chih‐Hung , Lee Jiun‐Haw 
Published: July 2011

AbstractIn this paper, High efficiency white organic light emitting diodes (OLEDs) have been analyzed not only through steady‐state characteristics but also transient measurement to understand the dynamics in OLEDs. After optimization, the quantum efficiency is reached to 12.88% at 1.04mA/cm2.
69.3: Spontaneously‐Formed Dual Groove Structure for Control of Azimuthal Anchoring and Pretilt in Liquid Crystal Alignment
Authors: Park Chang‐sub , Han Yeonjeong , Joo Kyung‐Il , Park Ji‐Sub , Park Min‐Kyu , Kang Shin‐Won , Kim Hak‐Rin 
Published: July 2011

AbstractIn this paper, we demonstrate a new surface patterning method for controlling the azimuthal anchoring energy and pretilt of liquid crystal alignment layer using topologically mixed surface patterns. In our method, the micro‐groove structure is spontaneously formed by the preparation, where the macro‐groove and micro‐groove surface pattern determine the surface pretilt and the azimuthal LC anchoring, respectively.
9.2: LTPS 5 Mask for 3.5″ WVGA Top Emission AMOLED Displays
Authors: Lee Iljeong , Im Choongyoul , Kim Youngdae , Kwon Dohyun , Kim Jongyun , Ko Moosoon , Yun Juwon , Yeo Jongmo , Im Jangsoon , Kim Sungchul 
Published: July 2011

AbstractThe world first LTPS 5 mask top emission active matrix organic light emitting diode AMOLED panel was fabricated by forming the data and the pixel in one step. Employing the coplanar structure of the pixel and the data line, we fabricated the 5 mask 3.5″ WVGA AMOLED successfully.
71‐1: Development of Micro‐Pixellated GaN LED Array Micro‐Display System
Authors: Sun Cheng‐Wei , Chao Chia‐Hsin , Chen Heng‐Yin , Chiu Yung‐Hsiang , Yeh Wen‐Yung , Wu Ming‐Hsien , Yen Hsi‐Hsuan , Liang Chao‐Chiun 
Published: July 2011

AbstractThis paper developed a micro‐pixellated GaN LED (μ‐LED) array micro‐display system. The μ‐LED array has the features of high luminance, small optical machine size, high collimation, and lost cost. A time‐separate driving method is proposed to drive the micro‐display system for releasing the LED over‐current and efficiency thermal degradation issues.
71.3: Flat‐Panel‐Display System Based on Interference Modulation for Both Intensity and Color
Authors: Ling Yuye , Gao Weilu , Ouyang Shihong , Liang Guoen , Su Yikai , Shieh Han‐Ping D. 
Published: July 2011

AbstractA novel flat‐pane‐display based on interference modulation for both intensity and color is presented. The system has the potential to sextuple the optical efficiency of the current TFT‐LCD technology, and an improved configuration can achieve comparable display quality as that of TFT‐LCD, enabling it as a promising display solution to handheld devices.
72.4: Invited Paper: Novel Approaches for OLED Lighting
Authors: Freitag Patricia , Hofmann Simone , Furno Mauro , Rosenow Thomas C. , Reineke Sebastian , Lüssem Björn , Mogck Stefan , Wański Tomasz , May Christian , Leo Karl 
Published: July 2011

AbstractIn this paper, we discuss novel approaches for organic light‐emitting diode (OLED) lighting application. In particular, we discuss OLED deposited by vacuum deposition on flexible substrates such as plastic and metal foils. We discuss the specific challenges of OLED design for such substrates, in particular when top‐emitting structures are required. Furthermore, we discuss a novel vacuum roll‐to‐roll tool which is capable of depositing oligomer OLED with high efficiency.
P‐2: Cross‐talk Caused by Light Reflected on the Back‐face of the LCD Glass in an Auto‐stereoscopic Display Using the Field‐sequential Method and a Directional Backlight System
Authors: Hayashi Akinori , Sakai Akira , Kometani Tomohiro , Ito Hiroshi 
Published: July 2011

AbstractTwo prototypes of full‐panel resolution auto‐stereoscopic LCD have been developed [1]. One of them uses the field‐sequential (time‐sequential) method and a directional backlight system. This paper mainly describes optical cross‐talk factors of it and a fact that reflection on the back‐face of the LCD glass is the most significant one. This can be a problem in other auto‐stereoscopic LCDs with a structure similar to ours.
P‐4: Measurement and Analysis of a Novel Full‐Parallax Three Dimensional Display System
Authors: Peng Yifan , Li Haifeng , Li Shuai , Liu Xu 
Published: July 2011

AbstractThis paper provides some imaging performance measurements and analysis for a prototype‐equipment based on a novel full‐parallax 3D display system. The projection center offset and crosstalk situation are mainly analyzed. Imaging performance of this 3D display system can be improved according to the analysis with the minimum changes to the system structure.
P‐8: Analysis of Temperature Dependence of 3D Viewing Space for Autostereoscopic Displays
Authors: Wu Di , Sakamoto Michiaki , Shigemura Koji , Asada Hideki 
Published: July 2011

AbstractFor autostereoscopic displays with plastic optical films such as lenticular lenses, the 3D viewing space varies with the temperature. Through theoretical analysis and experiments, we find that their changes behave differently for the near objects and far objects. Taking this result into consideration, a novel temperature compensation system is proposed and is also verified.
P‐10: Design for AMOLED Display with an Improved Uniformity and a Smaller Bezel
Authors: Huh Jin , Wang Se‐Won , Cho Gyu‐Hyeong , Park Youngju , Kim Jungchul 
Published: July 2011

AbstractA new pixel circuit and an integrated small sized scan driver for Active Matrix Organic Light Emitting Diode (AMOLED) Display are proposed in this paper. It is found that the effective mobility reduction by the gate‐source voltage of the driving TFT (DTFT) increases the sampling error of threshold voltage (Vth) with shortened sampling time. To solve this problem, a new pixel circuit and a even & odd driving scheme to increase sampling time of Vth is proposed for AMOLED display operating at high frame frequency such as 120 Hz or 240 Hz. For more compact displays, a new small sized scan driver is also proposed to reduce an area of bezel. The proposed circuits are verified by simulations.
P‐15: Bias Stress Reliability for w/ and w/o Oxide‐passivated IGZO TFTs
Authors: Tu Chun‐Hao , Lin Wei‐Ting , Chen Chia‐Hsiang , Hung Ming‐Chin , Chang Jiun‐Jye , Chiang Ming‐Feng , Liao Wei‐lung 
Published: July 2011

AbstractThe behaviors of dynamic gate bias stress for Indium‐Gallium‐Zinc‐Oxide (IGZO) TFTs were investigated in this study. The device after storage represents a parasitic traneffect after positive gate bias stress. Furthermore, the stability of IGZO TFTs can be improved by adding passivation layer.
P‐17: Body Voltage Modulation for High Performance a‐IGZO TFT and its Application on New Inverter Structure
Authors: Zan Hsiao‐Wen , Chen Wei‐Tsung , Hsueh Hsiu‐Wen , Yeh Chun‐Cheng , Tsai Chuang‐Chuang , Meng Hsin‐Fei , Yeh Chia‐Chun , Shinn Ted‐Hong 
Published: July 2011

AbstractWe develop a new and simple method to adjust the threshold voltage of a‐IGZO TFT by capping different metals on device back channel. A threshold voltage shifts from −7.4V to +5.5V can be obtained. The field‐effect mobility is 2 to 3 times larger than the one before metal capping. An n‐type a‐IGZO inverter includes one enhancement‐mode TFT (capped by titanium) and one depletion‐mode TFT (capped by calcium/aluminum dual layer) is fabricated. The voltage gain is 38 when the bias voltage is 20 volts.
P‐20: Highly Stable Amorphous Indium Gallium Zinc Oxide Thin‐Film Transistors with N2O Plasma Treatment
Authors: Yim Hoon , Kim Dae‐Hwan , Choi SeungChan , Choi Byung Gook , Lee Sul , Kim Sung Ki , Park Kwon‐Shik , Bae Jong‐Uk , Kim Chang‐Dong , Jun Myungchul , Hwang Yong Kee 
Published: July 2011

AbstractAmorphous InGaZnO4 (a‐IGZO) thin film transistors (TFTs) are promising devices in backplane technology. Since a‐IGZO TFTs are very sensitive to the fabrication processes, they need stable process to keep their initial deposition properties. Herein we improved the stability of a‐IGZO by applying N2O plasma. The stability characteristic of a‐IGZO TFT was improved with N2O plasma. Vth shift was 1.5V for 10,000s under NBTS with illumination which was the best result in the world.
P‐24: Low Power a‐Si:H TFT Gate Driver Circuit Employing Negative Turn Off Biasing
Authors: Lee JaeHoon , Bae YuHan , Lee WheeWon , Kim YoungSoo , Song JunYong , Hyun Youmee , Cho DucHan , Kim SungMan , Kwon YeongKeun , Kwon MinSung , Moon SeungHwan , Kim Kyeong‐Hyeon 
Published: July 2011

AbstractNew a‐Si:H TFT gate driver circuit (ASG) for low power consumption is proposed and fabricated. For the first time, the proposed ASG can set TFT turn off voltage to the negative voltage rather than zero voltage that the conventional one uses, therefore, TFT leakage current can dramatically be reduced by 1/100. The size of TFT in new ASG, which discharges the leakage current, can be reduced so that the power consumption of new ASG is 43% of the conventional one.
P‐34: Active Matrix Programmable Monolithic Light Emitting Diodes on Silicon (LEDoS) Displays
Authors: Liu Zhao Jun , Wong Ka Ming , Chong Wing Cheung , Lau Kei May 
Published: July 2011

AbstractIn this paper, the first full‐color active matrix programmable monolithic Light Emitting Diodes on Silicon (LEDoS) displays are fabricated using flip‐chip technology. The forward voltage uniformity of the LED pixels was greatly improved by a double‐side ground structure. A basic LED micro‐array module was fabricated and the AM substrate has scaling‐up ability. By integrating a certain number of LED micro‐array modules onto a large‐scale AM substrate, a large‐scale display is obtained. By this scaling‐up method, the utilization rate of the LED wafers is increased significantly. The yield of the LED pixels is improved simultaneously. Red, green and blue phosphors were excited by UV light to realize a full‐color display.
P‐203L: Late‐News Poster: Analytical I‐V and C‐V Models for Amorphous InGaZnO TFTs and Their Application to Circuit Simulations
Authors: Bae Minkyung , Kim Yongsik , Kim Woojoon , Kong Dongsik , Jung Hyunkwang , Jeon Yong Woo , Kim Sungchul , Hur Inseok , Kim Jaehyeong , Kim Dong Myong , Kim Dae Hwan , Kim Sun Il , Park Jae Chul , Kim Chang‐Jung , Du Ahn Byung , Park Sei Yong , Park Jun‐Hyun , Kim Joo Han , Park Jaewoo , Lee Je‐Hun 
Published: July 2011

AbstractAnalytical current and capacitance models for amorphous Indium‐Gallium‐Zinc‐Oxide Thin film transistors (a‐IGZO TFTs) are proposed for application to the simulation of a‐IGZO TFT‐based circuits. The accuracy of the proposed models are verified by comparing the measured I‐V and C‐V characteristics with calculated ones and the simulation result of a‐IGZO TFT‐based circuits. The proposed models are expected to be useful both for the optimization of fabrication process and for the prospective estimation of the effect of process conditions on the circuit performance.
P‐36: Touch Panel Display Filtering for Portable Night Vision Compatible Devices
Authors: Young Scott , Gaudette Claude , Phipps Benjamin 
Published: July 2011

AbstractA series of thick films has been developed using a colored polymeric for use on small and medium‐area displays requiring both touch compatibility and low Near Infrared (NIR) emissions. The films are designed to optimize energy emissions in the NIR with minimal degradation in sensitivity or color rendering while also maintaining the advantages of single and multi‐touch color displays.This paper attempts to touch upon the challenges to address in designing a filtering material for such application environments. The paper will also compare the advantages of these new generation materials to existing materials such as tacky polymers that often create undesired contact triggering, optical interference and contamination damage to the display surface.
P‐41: Optimization of Sub‐pixel Area for Multi‐primary Displays Based on Preferred Image Performance
Authors: Chu‐Ke Hui , Cheng Sheng‐Wen , Sun Wei‐Chieh , Yu Jian‐Shen 
Published: July 2011

AbstractMulti‐primary color (MPC) technology is used to achieve not only wide gamut color reproduction but brightness enhancement. With modifying the sub‐pixel areas of MPC, different imaging quality is performed. This paper reports a method to render the optimized ratio of sub‐pixel area for multi‐primary displays. This optimized ratio of sub‐pixel area provides a image‐based gamut for better image quality. We demonstrate the display with optimized ratio of sub‐pixel areas (R:G:B:Y = 5:3:5:3) that the image performance is better than other sub‐pixel area designs. 5. References
P‐42: Evaluation of the Ability to Reproduce Preferred Colors for Mobile Displays under Ambient Illumination Condition
Authors: Park Tae‐Yong , Jang Jun Woo , Shin Kwang‐Hoon , Yoo Jang Jin , Shin Hyun‐Ho 
Published: July 2011

AbstractThe focus of this paper is to evaluate the ability to reproduce preferred colors for mobile displays under ambient illumination condition. Mobile liquid crystal display (LCD) and active matrix organic light emitting diode (AMOLED) are used and 3D gamut volume in CIECAM02 QMh space is utilized to take absolute perceptual attributes into account. The ‘degree of inclusion (DOI)’ is calculated from the quantity of colors included within display gamut volume among the preferred colors of 1260 from six categories of image database. As a result of this evaluation, the ability of LCD to reproduce preferred colors is similar with a level of AMOLED due to its high brightness under general office environment.
P‐45: A Quality Measurement Based on Object Formation for 3D Contents
Authors: Li Chung‐Te , Lai Yen‐Chieh , Wu Chien , Cheng Chao‐Chung , Chen Liang‐Gee 
Published: July 2011

AbstractIn this paper, we propose a quality metric for three‐dimensional images or videos. The goal of this work is to provide a quality measurement from the relationship between the depth image quality and the three‐dimensional perception. From our observation, we found that there is a relation between the perception of depth and the formation of object. The consistency for depth and object perceptions has a strong influence on the acceptable visual quality in three‐dimensional images. Since the visual quality depends on the consistency, additional work is necessary for developing objective metrics based on this concept. In this paper, we propose a quality measurement metric for three‐dimensional images by checking the consistency between depth and object. The measured visual quality can be used as feedback for developing depth generation algorithms, which is important for 3D industry.
P‐46: A Color Space Derived from CIELUV for Display Color Management
Authors: Wen Senfar 
Published: July 2011

AbstractA color space derived from CIELUV is proposed for representing the color gamut of a color device in cylindrical shape. The proposed color space is device‐independent, suitable for the color gamut mapping in a color management system, and efficient for the utilization of signal bit depth.
P‐49: Design of Digital Time‐Modulation Pixel Memory Circuit on Glass Substrate for Low Power Application
Authors: Chen Szu‐Han , Ker Ming‐Dou , Wang Tzu‐Ming 
Published: July 2011

AbstractA digital time‐modulation pixel memory circuit on glass substrate has been designed and verified in a 3‐μm low temperature poly‐silicon (LTPS) technology. The proposed circuit can generate 4‐bit digital codes and the corresponding inversion data by time‐modulation technique to refresh the static image without activating the data driver circuit. Therefore, the data driver of liquid crystal display (LCD) panel is not required to provide the image data of the frame by the proposed circuit while the LCD panel operates in the still mode. The power consumption from data driver can be further reduced in the LCD panel.