bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childhood cancer models of survivorship care: a scoping review of elements of care and reported outcomes
Authors: Bradford Natalie , Chan Raymond Javan , Skrabal Ross Xiomara , Thamm Carla , Sharwood Erin , Pole Jason , Cashion Christine , Nekhlyudov Larissa 
Published: May 2024

Abstract
Purpose
This study aimed to systematically map elements of care and respective outcomes described in the literature for different models of post-treatment care for survivors of childhood cancer.

Methods
MEDLINE, CINAHL, and Embase were searched with combinations of free text terms, synonyms, and MeSH terms using Boolean operators and are current to January 2024. We included studies that described post-treatment cancer survivorship models of care and reported patient or service level elements of care or outcomes, which we mapped to the Quality of Cancer Survivorship Care Framework domains.

Results
Thirty-eight studies with diverse designs were included representing 6101 childhood cancer survivors (or their parent/caregiver) and 14 healthcare professionals. A diverse range of models of care were reported, including paediatric oncologist-led long-term follow-up, multi-disciplinary survivorship clinics, shared-care, and primary care-led follow-up. Elements of care at the individual level most commonly included surveillance for cancer recurrence as well as assessment of physical and psychological effects. At the service level, satisfaction with care was frequently reported but few studies reported how treatment-related-late effects were managed. The evidence does not support one model of care over another.

Conclusions
Gaps in evidence exist regarding distal outcomes such as costs, health care utilization, and mortality, as well as understanding outcomes of managing chronic disease and physical or psychological effects. The findings synthesized in this review provide a valuable reference point for future service planning and evaluation.

Implications for Cancer Survivors
Decades of research highlight the importance of survivorship care for childhood cancer survivors who are at risk of serious treatment-related late effects. This review emphasizes there is no single, ‘one-size fits all’ approach for delivering such care to this vulnerable population.
Biologischer Abbau von Aminophosphonaten
Authors: Riedel Ramona , Commichau Fabian , Benndorf Dirk , Martienssen Marion 
Published: May 2024

AbstractApplication of commercial aminophosphonates such as glyphosate (GS) or chelating agents in detergent are daily used at large scale worldwide. Only little is known about the potential biodegradation of the latter. Here we describe the characterization of the new strain Ochrobactrum sp. BTU1 isolated from a LC/MS standard solution. The strain is capable to degrade all investigated aminophosphonates including GS.
Vesikel-gebundene und frei zirkulierende miRNAs in Alterungsprozessen
Authors: Wagner Viktoria , Keller Andreas 
Published: May 2024

AbstractAltered intercellular communication is one of the molecular hallmarks of aging. Microvesicles carrying different kinds of molecules, like proteins and RNAs are important agents of short- and long-range communication in the body. MicroRNAs (miRNAs) are especially interesting targets to study in this context, as these molecules can regulate multiple targets in the recipient cells via complementary base-pair binding and thereby regulate a complex process such as aging.
Sectorial evaluation and characterization of internal marketing orientation through multicriteria analysis
Authors: Muñoz María M. , Kazakov Sergey , Ruiz-Alba Jose L. 
Published: May 2024

AbstractThis research carries out a comparative analysis of the Internal Market Orientation (IMO) to a sample of small and medium enterprise companies, which has been divided into nine groups based on their business sectors. Applying the statistical technique of structural equations, the coefficients of four IMO inputs in each business sector are obtained. Next, the PROMETHEE multicriteria technique is applied to obtain a composite indicator of the IMO implementation of each business sector. The value of the composite indicator together with the GAIA plane allow to distinguish the differences of the IMO profiles, their strengths and their weaknesses. The results show the divergences in the IMO inputs according to the sector, which is evidence that the business sector is a predictor of the IMO implementation of a company.
Wastewater purification and recycling using plants in an arid environment for agricultural purposes: case of the Algerian Sahara
Authors: Bendida Ali , Kendouci Mohammed Amin , Mebarki Saliha , Tidjani Abdellatif El-Bari 
Published: May 2024

AbstractThe aim of this study is to apply a water treatment technique (phyto-purification) in the Algerian Sahara, an arid region, to resolve the scarcity of irrigation, recycled wastewater and preserve Saharian ecosystems composed of sand and two species of aquatic plants: Typha latifolia and Imperata cylindrica. The choice of these plants was determined based on the natural vegetation, soil and climatic characteristics of the study area. To this end, we developed an experimental pilot composed of three tanks measuring 30 cm × 35 cm × 45 cm, arranged with a filter bed of sand and gravel. Two of these tanks are sown with the above-mentioned plants, while the third tank, serving as a control, is not. The values of the main wastewater pollution parameters, namely total nitrogen compounds, ammonium (NH4+), chemical oxygen demand (COD) and suspended solids measured at the outlet of the device, substantiate the performance of this treatment system. Indeed, the nitrogen reduction rate increased from 63% in the unplanted control filters to around 80% in the planted filters, and from 81 to 88% for NO3−. Regarding chemical oxygen demand (COD), the reduction rate exceeds 88.37% for the three tanks. The study of the analytical approach to modeling the purification kinetics reveals that the kinetics of COD and NH4+ are well correlated with the first-order model, with an explained variance varying between 68.1 and 81.6% for COD and 83.5 and 92.3% for ammonium. The Riverside diagram highlights that all treated water samples fall into the low sodium risk and high salinity risk class. Build on the Na% values; all purified waters have characteristics suitable for water use for irrigation.
The analysis of transcriptomic signature of TNBC—searching for the potential RNA-based predictive biomarkers to determine the chemotherapy sensitivity
Authors: Supplitt Stanislaw , Karpinski Pawel , Sasiadek Maria , Laczmanski Lukasz , Kujawa Dorota , Matkowski Rafal , Kasprzak Piotr , Abrahamowska Mariola , Maciejczyk Adam , Iwaneczko Ewelina , Laczmanska Izabela 
Published: May 2024

Abstract
Neoadjuvant chemotherapy is the foundation treatment for triple-negative breast cancer (TNBC) and frequently results in pathological complete response (pCR). However, there are large differences in clinical response and survival after neoadjuvant chemotherapy of TNBC patients. The aim was to identify genes whose expression significantly associates with the efficacy of neoadjuvant chemotherapy in patients with TNBC. Transcriptomes of 46 formalin-fixed paraffin-embedded (FFPE) tumor samples from TNBC patients were analyzed by RNA-seq by comparing 26 TNBCs with pCR versus 20 TNBCs with pathological partial remission (pPR). Subsequently, we narrowed down the list of genes to those that strongly correlated with drug sensitivity of 63 breast cancer cell lines based on Dependency Map Consortium data re-analysis. Furthermore, the list of genes was limited to those presenting specific expression in breast tumor cells as revealed in three large published single-cell RNA-seq breast cancer datasets. Finally, we analyzed which of the selected genes were significantly associated with overall survival (OS) in TNBC TCGA dataset. A total of 105 genes were significantly differentially expressed in comparison between pPR versus pCR. As revealed by PLSR analysis in breast cancer cell lines, out of 105 deregulated genes, 42 were associated with sensitivity to docetaxel, doxorubicin, paclitaxel, and/or cyclophosphamide. We found that 24 out of 42 sensitivity-associated genes displayed intermediate or strong expression in breast malignant cells using single-cell RNAseq re-analysis. Finally, 10 out of 24 genes were significantly associated with overall survival in TNBC TCGA dataset. Our RNA-seq-based findings suggest that there might be transcriptomic signature consisted of 24 genes specifically expressed in tumor malignant cells for predicting neoadjuvant response in FFPE samples from TNBC patients prior to treatment initiation. Additionally, nine out of 24 genes were potential survival predictors in TNBC. This group of 24 genes should be further investigated for its potential to be translated into a predictive test(s).
Moduli space of bi-invariant metrics
Authors: Flores Torres Juan 
Published: May 2024

AbstractIn this work, we focus on describing the space of bi-invariant metrics in a Lie group up to isometry. i.e, metrics invariant under both left and right translations. We show that $$\mathfrak {BI}$$
BI
, the moduli space of bi-invariant metrics, is an orbifold. Moreover, we give an explicit description of this orbifold, and of $$\mathfrak {EBI}$$
EBI
, the space of bi-invariant metrics equivalent under isometries and scalar multiplies.
Recent Developments in RFT Encourage Interbehavioral Field-Based Views of Human Language and Cognition: A Preliminary Analysis
Authors: Harte Colin , Barnes-Holmes Dermot 
Published: May 2024

AbstractRelational frame theory (RFT) as a behavior-analytic approach to understanding human language and cognition is now over 40 years old. However, the last 8 years have seen a relatively intense period of empirical and conceptual developments within the theory. Some of this work has begun to draw on early and much underplayed features of RFT, including field-theoretical analyses and concepts. These analyses are relatively nascent and thus the current article aims to provide a relatively detailed example of a field-theoretical analysis of a specific RFT research program. We begin with a brief overview of the “traditional” RFT approach to human language and cognition, followed by a summary of recent research involving the implicit relational assessment procedure (IRAP) and the differential arbitrarily applicable relational responding effects (DAARRE) model. We then go on to consider the DAARRE model in the context of J. R. Kantor’s interbehavioral formula for the psychological event. Having done so, we conclude that the challenge involved in analyzing increasingly complex forms of human language and cognition appears to call for more field-based theorizing in some form or another.
The Role of Organized Activities in Supporting Youth Social Capital Development: A Qualitative Meta-Synthesis
Authors: Boat Ashley A. , Poparad Heather , Seward Miray D. , Scales Peter C. , Syvertsen Amy K. 
Published: May 2024

AbstractSocial capital provides young people with a web of supportive relationships that can be leveraged in pursuit of education, career, and life goals. Organized activities, an umbrella term for extracurricular activities, after-school programs, and youth development programs, are important developmental contexts for building social capital. The purpose of this study was to illuminate the developmental pathway through which social capital development occurs in organized activities. A qualitative meta-synthesis was conducted using 33 articles that met inclusion criteria across five databases (e.g., ERIC, PsycINFO) between June 2022 and May 2023. Thematic analysis was used to identify malleable organized activity features that act as levers for social capital promotion. Seven thematically aligned features were identified, including (1) organizational partnerships, (2) organizational supporting structures, (3) relationally strong climate, (4) staff mindsets and skills, (5) youth mindsets and skills, (6) increased social capital opportunities, and (7) increased social capital activation. These seven themes were used to construct an empirically-grounded model that posits a process through which organized activities support youth social capital development. Implications for intentionally strengthening organized activities’ capacity to support youth social capital are discussed.
Mechanism of overburden fracture induced earthquakes in coal seam mining
Authors: Zhang Quan , Zou Junpeng , Jiao Yu-Yong , Jiang Yujing , Kou Qihua 
Published: May 2024

AbstractMining-induced earthquakes are unnatural seismic events that frequently occur in high-position hard and thick rock strata during coal mining. Considering the frequent occurrence of strong mining-induced earthquakes in the Dongtan mining area, this study analysed the fracture migration characteristics of hard and thick rock strata and the focal mechanism of mining-induced earthquakes based on Volasov’s thick-plate and moment tensor inversion theories. The results showed that the main key strata were difficult to break under single-panel mining conditions because of the thick and high-strength rock strata and breakage of the main key strata is caused by multiple-panel mining. Volasov’s thick-plate theoretical calculation indicated an initial fracture span of the main key strata was 314 m, which is consistent with the actual mining distance of the working face. This verified that strong mining-induced earthquakes were induced by the initial fracture of the main key strata. In coal mining, the pure shear failure type of mining-induced earthquakes indicated the highest percentage, and the shear fracture of rock strata was the primary cause of strong mining-induced earthquakes. The dip angle of the focal fracture surface in mining-induced earthquakes was generally within 15°. Through an analysis of the focal mechanism of mining-induced earthquakes, it has a certain guiding role in explaining the mechanism of mining-induced earthquakes.
The Port Macquarie Settlement, New South Wales, 1821–1847: Interconnections within Landscapes of Convict Labor and Industry
Authors: Phillips Crystal , Gibbs Martin 
Published: May 2024

AbstractThis article explores the convict-punishment settlement of Port Macquarie on the mid-north coast of New South Wales between 1821 and 1847. Synthesizing previous and new historical and archaeological research, it identifies a range of major and minor sites of labor, accommodation, reform, and punishment within the settlement’s landscape during its period as a restricted convict prison from 1821 to 1830. From this it reconstructs the network of labor provision and infrastructure development, which we argue was not just about making the settlement economically self-sustaining, but also intended to create the framework for a transition to a “free” settlement. To this end this article also examines the ways in which that transformation occurred, with former sites of convict labor and the convicts themselves transitioning from government control to private settlers, until the withdrawal of the government infrastructure for convict management in 1847.
A comprehensive review on the health benefits, phytochemicals, and enzymatic constituents for potential therapeutic and industrial applications of Turkey tail mushrooms
Authors: Camilleri Emma , Blundell Renald , Baral Bikash , Karpiński Tomasz M. , Aruci Edlira , Atrooz Omar M. 
Published: May 2024

AbstractThis comprehensive literature review delves into the multifaceted attributes of Trametes versicolor, commonly known as turkey tail mushroom. The turkey tail mushroom stands as a noteworthy source of diverse bioactive compounds with potent health benefits. This review offers a contemporary synthesis of its phytochemical constituents and their multifaceted impacts on human health. The mushroom's intricate composition, encompassing polysaccharides, phenols, and triterpenes, underpins its remarkable therapeutic potential. Focusing on key attributes such as anti-cancer, anti-microbial, and immunomodulatory activities, this review delves into the intricate mechanisms by which the turkey tail mushroom exerts its effects. In addition, the exploration extends to the enzymatic constituents inherent in the mushroom and their industrial significance. Mechanisms of action for both phytochemicals and enzymes are studied, providing a well-rounded understanding of their roles in conferring therapeutic and industrial benefits. This synthesis of research aims to provide an up-to-date perspective on turkey tail mushrooms' versatile applications. By intertwining the exploration of health benefits and enzymatic constituents, this review offers insights into the potential of harnessing this natural resource for innovative therapeutic strategies and industrial applications. Overall, it contributes to the advancement of knowledge and utilisation of turkey tail mushrooms' diverse properties for human health and industrial progress.
The Alteration in Physiological Status, Growth and Essential Oil Profile of French Marigold (Tagetes patula L.) Owing to Seaweed Extract and Salicylic Acid Application
Authors: El-Ziat Rasha Ahmed Mohamed , Saudy Hani Saber , Hewidy Mohammed 
Published: May 2024

Abstract
Purpose
Medicinal plants show a relevant importance in human life and health. The use of natural substances in crop management is not only significant for the plant healthy growth and yield, but also for obtaining safe products. The study aimed to examine the effect of seaweed extract (SW) as a natural source of nutrition and salicylic acid (SA) on plant health, physiology and essential oil profile of French marigold (Tagetes patula L.).

Methods
Three levels of salicylic acid, SA50, SA100 and SA200, (50, 100, and 200 mg L− 1) and three levels of seaweed extract, SW2, SW4 and SW6 (2.0, 4.0, and 6.0 ml L− 1), in comparison with control treatment (tap water) were applied as foliar sprayings. The seven treatments were arranged in randomized complete block design and were replicated thrice in two growing seasons (2020 and 2021).

Results
Findings pointed out that SA200 increased plant height, branches number plant− 1, stem diameter, leaf area, leaves number plant− 1, plant fresh weight, and plant dry weight by 32.9, 112.2, 59.2, 34.4, 44.3, 33.0 and 56.9% (averages of the two seasons), respectively, compared to the control treatment (tap water). SW6 increased carotenoids content by 34.8 and 46.4% in 2020 and 2021 seasons, respectively. Salicylic acid at the rate of 200 mg L− 1 along seaweed extract at 6 ml L− 1 gave the highest values of total sugars and free amino acids. SA200 alone recorded the maximal value of peroxidase activity surpassing the other treatments. SW6 possessed the greatest essential oil content in both seasons, statistically equaling SA200 in the first season. Huge variations in essential oil profile were recorded under the tested trial treatments.

Conclusion
It could be concluded that salicylic acid and seaweed extract foliar application unveiled their involvement in diverse physiological and developmental responses; pigment formation, enzyme activities, flower induction, nutrient uptake, essential oil metabolism, and overall plant growth and development. It is recommended to use the highest concentrations of the tested substances (SA at 200 mg L− 1 or SW at 6.0 ml L− 1) for achieving distinctive improvements in physiological responses of French marigold plant.
The Performance of Modified Asphalt Mixtures with Different Lengths of Glass Fiber
Authors: Khaled Teba Tariq , Kareem Abbaas I. , Mohamad Safaa A. , Al-Hamd Rwayda Kh. S. , Minto Andrew 
Published: May 2024

AbstractOne practical option for modifying an asphalt mixture’s performance is to use additives. This will help the mixture perform better against the damaging effects of traffic, loads, and climatic variations. In this regard, glass fiber (GF) has drawn much interest because of its positive effect. Therefore, this paper attempts to study the effect of glass fiber length and content on the performance and strength of asphalt mixtures. It also aims to determine the optimum glass fiber content and the best glass fiber length of modified asphalt mixtures. An experimental program is carried out, which includes the Marshall test, volumetric properties, freeze-thaw splitting test, immersion Marshall test, and wheel tracking test to characterize related properties of glass fiber incorporated in asphalt mixtures. Seven different percentages (0, 0.25, 0.5, 0.75, 1, 1.25, and 1.5) of glass fiber by total weight of aggregates in three various lengths are used to design 19 asphalt mixtures. Based on the results obtained, the performance of the asphalt mixture was enhanced remarkably after adding glass fiber. The use of various lengths of glass fiber led to a better-quality asphalt mixture in terms of volumetric properties, moisture damage resistance, and permanent deformation resistance. Specifically, asphalt mixtures made with (0.5%) glass fiber illustrated the highest quality, and adding (20 mm) length of glass fiber was better than (10 mm and 30 mm) glass fiber lengths. The results also show that adding (10 mm and 30 mm) lengths of glass fiber can improve the resistance of asphalt mixtures to water damage and permanent deformation compared with the control mixture (M0). The findings indicate the applicability of 20 mm glass fiber length in asphalt mixtures to achieve better resistance against moisture and reduce the chance of irreparable permanent deformation under growing traffic loads and hot climate changes. Although the inclusion of glass fiber in asphalt mixtures led to a modest increase (6%) in overall cost, the effective improvement in performance and extension of the service life of the asphalt pavement constitute a convincing argument for this approach, making it an attractive option. Finally, it was concluded that a higher amount of glass fiber (i.e., > 0.5%) and a length greater than (20 mm) could diminish the positive effect of glass fiber to improve the properties of glass fiber asphalt mixtures.
Factors Affecting Shooting Performance in Laser Run
Authors: Hoffmann Christine 
Published: May 2024

Abstract
Purpose
Laser Run combines running and shooting with a laser pistol in multiple laps with high cardio-vascular stress. The aim of this study was to analyze the impact of shooting rate, shooting rhythm, heart rate, and core stability on the overall performance.

Methods
During a qualification race with 23 elite athletes heart rate and shooting performance were measured. The shooting rate and rhythm were then calculated and trunk strength endurance was determined in a separate test.

Results
Firing an average of 10.2 ± 3.9 shots per lap, the athletes spent a mean of 23.0 ± 12.0 s at the shooting range. The mean shooting rate was approximately 2.4 s between two shots. The results indicated a regular shooting rhythm to be more important than high shooting rate. The variation of the shooting rate showed a strong correlation with the overall shooting performance (r = 0.77). Athletes shoot at a heart rate close to 95% of their maximum heart rate. However, deviations do not seem to influence on the shooting performance, whereas core strength endurance obviously has a strong impact on shooting performance (r = −0.57).

Conclusion
Athletes must train to shoot with high heart rates and find a balance between high shooting rate and precision. A constant shooting rhythm and good core stability appear to be particularly important for high performance.