bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Two New Stereoisomers of Neolignan (I) and Lignan (II) from the Flower Buds of Magnolia fargesii.
Authors: Lee Jun , Seo Eun‐Kyoung , Jang Dae Sik , Ha Tae Joung , Kim Jong‐Pyung , Nam Joo‐Won , Bae Green , Lee Yun Mi , Yang Min Suk , Kim Jin Sook 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cytotoxic Prenylated Flavonoids from the Stem Bark of Maackia amurensis.
Authors: Li Xiong , Wang Dong , Xia Ming‐yu , Wang Zhi‐hui , Wang Wei‐ning , Cui Zheng 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry, Physical Chemistry, and Uses of Molecular Fluorocarbon—Hydrocarbon Diblocks, Triblocks, and Related Compounds — Unique “Apolar” Components for Self‐Assembled Colloid and Interface Engineering
Authors: Krafft Marie Pierre , Riess Jean G. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Application of Peptide Arrays: Quo Vadis SPOT Technology
Authors: Volkmer Rudolf 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis of 5a‐Carbaglycopyranosylamine Glycosidase Inhibitors
Authors: Ogawa Seiichiro , Kanto Miki 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Quinazolines as Tyrosine Kinase Inhibitors
Authors: Srivastava Sanjay K. , Kumar Vivek , Agarwal Shiv K. , Mukherjee Rama , Burman Anand C. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Interaction of 1,3‐Diheteracycloalkanes with Diazo Compounds
Authors: Sultanova Rimma M. , Khanova Marina D. , Dokichev Vladimir A. 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Induction on β‐Boration of α,β‐Unsaturated Compounds — An Inexpensive Approach
Authors: Lillo Vanesa , Bonet Amadeu , Fernandez Elena 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Time‐Resolved Electron Paramagnetic Resonance Studies of Transient Organic Radicals
Authors: Beckert Dieter 
Published: August 2009

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Evaluation of dalbavancin as chiral selector for HPLC and comparison with teicoplanin‐based chiral stationary phases
Authors: Zhang Xiaotong , Bao Ye , Huang Ke , Barnett‐Rundlett Kimber L. , Armstrong Daniel W. 
Published: August 2009

AbstractDalbavancin is a new compound of the macrocyclic glycopeptide family. It was covalently linked to 5 μm silica particles using two different binding chemistries. Approximately 250 racemates including (a) heterocyclic compounds, (b) chiral acids, (c) chiral amines, (d) chiral alcohols, (e) chiral sulfoxides and sulfilimines, (f) amino acids and amino acid derivatives, and (g) other chiral compounds were tested on the two new chiral stationary phases (CSPs) using three different mobile phases. As dalbavancin is structurally related to teicoplanin, the same set of chiral compounds was screened on two commercially available teicoplanin CSPs for comparison. The dalbavancin CSPs were able to separate some enantiomers that were not separated by the teicoplanin CSPs and also showed improved separations for many racemates. However, there were other compounds only separated or better separated on teicoplanin CSPs. Therefore, the dalbavancin CSPs are complementary to the teicoplanin CSPs. Chirality, 2010. © 2009 Wiley‐Liss, Inc.
Katalysatorscreening bei der Umesterung von Fetten und Ölen mit Ethanol
Authors: Hagen J. , Henke Dipl.‐Ing. D. 
Published: August 2009

AbstractFettsäureethylester haben ein interessantes Entwicklungspotential für die Herstellung von Biodiesel. Die Ethanolyse von Fetten und Ölen lässt sich mit hohen Ausbeuten sowohl homogen katalysiert, als auch heterogen katalysiert bei höheren Reaktionstemperaturen durchführen. Auch Fette und Öle mit hohen Gehalten freier Fettsäuren lassen sich mit sauren Katalysatoren problemlos umestern. Die besten Katalysatoren waren Toluolsulfonsäure und Alkylbenzolsulfonsäure (homogen, 80 °C) sowie sulfatiertes ZrO2 und Montmorillonit KSF (heterogen, 140 – 160 °C).
An evaluation of lower‐body functional limitations among long‐term survivors of 11 different types of cancers
Authors: Schootman Mario , Aft Rebecca , Jeffe Donna B. 
Published: August 2009

AbstractBACKGROUND:The authors examined potential reasons (sociodemographics, psychologic distress, health behavior, chronic health conditions, access to medical care) for increased prevalence of lower‐body functional limitations among long‐term (≥5 years) cancer survivors.METHODS:The authors used National Health Interview Survey data from 2005 through 2007, and defined lower‐body functional limitation as reporting difficulty/inability to perform at least 1 of 5 activities (walking approximately one–quarter of a mile; walking up and down 10 steps without rest; standing for 2 hours; stooping, crouching, or kneeling; and lifting 10 lbs). Increased prevalence of lower‐body functional limitations was compared between long‐term survivors of each of 11 cancer types reported by ≥50 respondents (n = 2143) and persons without cancer history (controls; n = 72,618).RESULTS:Among cancer survivors, 57.0% had a lower‐body functional limitation versus 26.6% of controls. The unadjusted prevalence of lower‐body functional limitations varied by cancer type, ranging from 44.9% (lymphoma survivors) to 88.8% (lung cancer survivors). Long‐term lung (odds ratio [OR], 7.91), uterine (OR, 2.41), thyroid (OR, 2.27), cervical (OR, 1.76), ovarian (OR, 1.75), and breast (OR, 1.35) cancer survivors had increased odds of reporting a lower‐body functional limitation than controls after adjusting for sociodemographic factors (all P < .05). Differences in the prevalence of arthritis and lower‐back pain and in access to medical care explained differences in lower‐body functional limitation prevalence between controls and long‐term breast, cervical, ovarian, and uterine cancer survivors. Long‐term bladder, colorectal, lymphoma, melanoma, and prostate cancer survivors were equally likely to report a lower‐body functional limitation as controls.CONCLUSIONS:Treatment of arthritis and lower–back pain and increasing access to medical care might help reduce the risk of lower‐body functional limitations and improve quality of life among specific long‐term cancer survivors. Cancer 2009. © 2009 American Cancer Society.
Inhibited temperament and parent emotional availability differentially predict young children's cortisol responses to novel social and nonsocial events
Authors: Kertes Darlene A. , Donzella Bonny , Talge Nicole M. , Garvin Melissa C. , Van Ryzin Mark J. , Gunnar Megan R. 
Published: August 2009

AbstractPreschool‐aged children (n = 274) were examined in the laboratory to assess behavioral and cortisol responses to nonsocial and social threat. Parents also responded to scales on the Children's Behavior Questionnaire reflecting exuberant approach to novel/risky activities (reversed scored) and shyness. Multi‐method measures of Nonsocial and Social Inhibition were computed. Parents and children were observed engaging in a series of interactive tasks and the Emotional Availability scales were scored for parental sensitivity, nonintrusiveness, nonhostility, and structuring. These scores were factored to yield one measure of Parenting Quality. Analyses revealed that Nonsocial and Social Inhibition could be distinguished and that associations with cortisol response were stressor specific. Moderation analyses revealed that parenting quality buffered cortisol elevations for extremely socially, but not nonsocially inhibited children. These findings are consistent with evidence that sensitive, supportive parenting is an important buffer of the HPA axis response to threat in infants and toddlers, and extends this finding to the preschool period. © 2009 Wiley Periodicals, Inc. Dev Psychobiol 51: 521–532, 2009.
CD137 ligand‐mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: Involvement of mTOR/p70S6 kinase and Akt
Authors: Kim Dong‐Ku , Lee Sang Chul , Lee Hyeon‐Woo 
Published: August 2009

AbstractCross‐linking of CD137 ligand (CD137L), a member of the TNF family, with recombinant CD137‐Fc (rCD137‐Fc) protein enhanced adherence of bone marrow‐derived macrophages, and increased the expression of ICAM‐1, IL‐1β, IL‐6, M‐CSF and phosphotyrosine proteins. In RAW264.7 cells, a murine myeloid cell line, rCD137‐Fc not only increased adherence but also cell multiplication, in a manner comparable to LPS or M‐CSF. In addition, it up‐regulated expression of IL‐1β, IL‐1 receptor antagonist, IL‐6, COX2, tenascin C, neuropeptide Y and M‐CSF mRNA. Neutralization of M‐CSF by incubating the RAW264.7 cells with anti‐M‐CSF mAb did not prevent the CD137L signal‐induced viability. Viability was blocked by PP2, an Src tyrosine kinase inhibitor, rapamycin, an mTOR inhibitor and LY294002, a PI3K inhibitor, but not by Wortmannin, another PI3K inhibitor. Cross‐linking of CD137L increased phosphorylation of Akt and p70S6 kinase. The latter was blocked by PP2, rapamycin or LY294002, but not by Wortmannin, whereas phosphorylation of Akt was blocked by LY294002 or Wortmannin. These findings demonstrate that reverse signals evoked by CD137L regulate immune functions in macrophages.
Tissue transglutaminase enhances collagen type II‐induced arthritis and modifies the immunodominant T‐cell epitope CII260‐270
Authors: Dzhambazov Balik , Lindh Ingrid , Engström Åke , Holmdahl Rikard 
Published: August 2009

AbstractThe calcium‐dependent enzyme tissue transglutaminase (tTG) is associated with diverse biological functions, such as induction of apoptosis, modeling of the extracellular matrix, receptor‐mediated endocytosis, cell growth and differentiation, cell adhesion and signal transduction. Also, it may deamidate glutamine residues to glutamic acid and catalyze cross‐linking of proteins. In this study, we have investigated the impact of tTG for posttranslational modifications and cross‐linking of the immunodominant T‐cell epitope CII260‐270 and their effects on the collagen‐induced arthritis, an animal model for rheumatoid arthritis. By using mass spectrometry analysis and hybridoma assays, we have demonstrated that tTG could perform both types of modifications (deamidation and cross‐link formation) on the immunodominant T‐cell epitope CII259‐273. Replacement of the glutamine at position 267 with glutamic acid leads to a decreased binding affinity to MHC II. T cells recognized both non‐modfied (Q267) and modified (E267) CII259‐273‐peptides. We also show that administration of tTG leads to increased incidence, severity and histopathological manifestations of collagen‐induced arthritis in mice. Moreover, we conclude that both processes, deamidation and cross‐linking, are involved in the tTG‐catalyzed reactions, and in vivo administration of tTG enhances arthritis severity and joint destruction in mice.
Stable silencing of the glucocorticoid receptor in myelin‐specific T effector cells by retroviral delivery of shRNA: Insight into neuroinflammatory disease
Authors: Tischner Denise , van den Brandt Jens , Weishaupt Andreas , Lühder Fred , Herold Marco J. , Reichardt Holger M. 
Published: August 2009

AbstractAutoimmune responses in the CNS can be induced by adoptive transfer of CD4+ T effector cells after antigen‐restimulation and expansion of clonal cell lines in vitro. However, pathogenic factors remain partially elusive due to the lack of appropriate methods to achieve gene inactivation. Here we describe a protocol for stable gene silencing in differentiated rat T cells by retroviral transfer of small hairpin RNAs. Through the combination of an expression cassette containing the green fluorescent protein with a puromycin selection cassette this allows for the generation of pure knockdown cell lines suitable for tracking in animals. Exemplified for the glucocorticoid receptor, we demonstrate that gene silencing renders T effector cells unresponsive to ligand‐induced apoptosis and gene regulation without affecting their ability to induce EAE in rats. Interestingly, glucocorticoid administration remains effective in the treatment of EAE despite strongly diminished glucocorticoid receptor expression in antigen‐specific T cells. This highlights an important role of other cell types and bystander T cells as targets of glucocorticoid therapy. Collectively, our approach provides a simple tool for stable and efficient gene silencing in T effector cells, which should help to better understand brain autoimmune pathophysiology.
The Reasons for Ligand‐Dependent Quantum Yields and Absorption Spectrum of Four Polypyridylruthenium(II) Complexes with a Tetrazolate‐Based Ligand: TDDFT Study
Authors: Li Xiao‐Na , Wu Zhi‐Jian , Zhang Hong‐Jie , Si Zhen‐Jun , Zhou Liang , Liu Xiao‐Juan 
Published: August 2009

AbstractThe quantum yield, lifetime, and absorption spectrum of four [Ru(bpy)2L]+ [where bpy is 2,2′‐bipyridyl; L is represented by the deprotonated form of 2‐(1H‐tetrazol‐5‐yl)pyridine (L1) or 2‐(1H‐tetrazol‐5‐yl)pyrazine (L2)], as well as their methylated complexes [Ru(bpy)2LMe]2+ (RuL1Me and RuL2Me) are closely ligand dependent. In this paper, density functional theory (DFT) and time‐dependent DFT (TDDFT) were performed to compare the above properties among these complexes. The calculated results reveal that the replacement of pyridine by pyrazine or the attachment of a CH3 group to the tetrazolate ring greatly increases the π‐accepting ability of the ancillary ligands. The stronger π‐accepting ability of the ancillary ligands in RuL2 results in stronger interaction with polar solvents and a relaxed geometrical structure; these are the main reasons for the lowest quantum yields and the shortest lifetime. The electron‐donating CH3 group buffers the interaction between RuL2Me and the solvent, and together with the enhanced MLCT participation, these account for the highest quantum yields and the longest lifetime. This theoretical contribution allows the factors determining the efficiency of radiative and nonradiative decay pathways in this series of complexes to be rationalized and also allows design of new ruthenium(II) complexes with higher phosphorescence efficiency. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Molybdenum Carbonyl Complexes Bearing PN Ligands Based on 2‐Aminopyridine
Authors: Standfest‐Hauser Christina Maria , Dazinger Georg , Wiedermann Julia , Mereiter Kurt , Kirchner Karl 
Published: August 2009

AbstractMolybdenum complexes of the general formula Mo(PN)(CO)4containing both achiral and chiral phosphorus‐nitrogen donor bidentate ligands based on 2‐aminopyridine were prepared and characterized by their NMR and IR spectra. The oxidative addition of allyl bromide to Mo(PN)(CO)4was studied with PN =N‐(diisopropylphosphanyl)‐2‐aminopyridine (PN‐iPr). X‐ray structures of representative compounds were determined. The mechanism of the oxidative addition of allyl bromide to Mo(PN‐iPr)(CO)4was analyzed by DFT/B3LYP calculations. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
A New Organic‐Inorganic Hybrid Supermicroporous Material Having Luminescence and Ion‐Exchange Property
Authors: Chandra Debraj , Dutta Arghya , Bhaumik Asim 
Published: August 2009

AbstractA new crystalline microporous organic‐inorganic hybrid material containing a diimine fluorophore inside the framework has been synthesized solvothermally without using any template or structure‐directing agent (SDA). Powder XRD and N2 sorption analyses suggested the formation of a new triclinic phase and supermicropores of dimension 1.39–1.53 nm in this material. 13C CP MAS, 29Si MAS NMR, UV/Vis absorption and PL spectroscopic results suggested the presence of bridging organic diimine fluorophore in this new porous framework. Due to the use of sole fluorophore organosilane moiety in this organic‐inorganic hybrid framework, this material shows very large affinity toward metal cations like Fe3+, Zn2+, Cd2+ and Hg2+, and thus can be efficiently utilized as metal ion chemosensor and exchanger. All the metal ion‐exchanged samples show very strong photoluminescence at room temperature and strong dependence of emission colors when exchanged with a particular metal cation.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Microwave‐Assisted Palladium‐Catalyzed Heterogeneous Vinylation of 2(1H)‐Pyridones
Authors: Singh Brajendra K. , Cavalluzzo Claudia , De Maeyer Marc , Debyser Zeger , Parmar Virinder S. , Van der Eycken Erik 
Published: August 2009

AbstractA mild and efficient microwave‐assisted vinylation of 2(1H)‐pyridones has been developed using potassium vinyltrifluoroborate with palladium on carbon as the catalyst. Various vinylating agents, Pd sources and solvents have been screened. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Potentiometric Studies and Various Applications of Solid State Electrodes Based on Silicon and Epoxy Glass Structures – an Overview
Authors: Ciosek P. , Chudy Michał , Górski Łukasz , Grabowska Ilona , Grygołowicz‐Pawlak Ewa , Malinowska Elżbieta , Wróblewski W. 
Published: August 2009

AbstractPotentiometric microelectrodes are attractive sensor tools for the determination of ionic components in liquids, in wide area of applications, from environmental monitoring to medical diagnostics. Appropriate design of miniaturized transducers based on solid‐state technology and the fabrication of dedicated flow multiparameter systems allow the reduction of sample volume and reagents loss. In this overview various examples of the design, performance, and applications of solid‐state potentiometric microelectrodes based on back‐side contact transducers for flow‐cell analysis are presented. The presented results summarize the research works on that field that were conduced in CSRG/Warsaw University of Technology.
Microfabricated Amperometric Cells for Multicomponent Analysis
Authors: Liu Ying , Gyurcsányi Róbert E. , Jágerszki Gyula , DeNuzzio John D. , Lindner Ernő 
Published: August 2009

AbstractTowards the development of multianalyte electrochemical immunoassays three individually addressable microelectrode array (MEA) type working electrodes and a reference electrode were integrated into a 4 μL volume, planar electrochemical cell. To model the simultaneous determination of multiple antigens in the cell with enzyme linked immunosorbent assays (ELISAs) glucose oxidase (GOx), alkaline phosphatase (ALP), and β‐galactosidase (β‐GAL) were immobilized site specifically onto the individual MEA surfaces and the biocatalitic activity of these surface confined enzymes were evaluated by measuring the products of the enzyme catalyzed reactions directly on the gold MEA surfaces by chronoamperometry or by imaging the enzyme patterned microelectrode array surfaces by Scanning Electrochemical Microscopy (SECM). ALP and β‐GAL were selected as model enzymes because they are the most commonly used enzymes labels in ELISAs. In these measurements glucose, ascorbic acid phosphate (AAP), and p‐aminophenyl‐β‐D‐galactopyranoside (PAPG) served as enzyme substrates, respectively. The electrochemical surface area of the gold MEAs did not change during the multistep immobilization process. All enzyme modified MEAs presented selective and proportional responses to their substrates and the response characteristics of the enzyme modified sensors were identical in separate and simultaneous calibration protocols, i.e., there was no cross‐contamination between the closely placed MEAs. The SECM images of the enzyme patterned MEA surfaces suggest that nonspecific adsorption is negligible on the insulating polyimide surface of the MEA separating the individual microelectrode sites.
Direct DNA Hybridization on the Single‐Walled Carbon Nanotubes Modified Sensors Detected by Voltammetry and Electrochemical Impedance Spectroscopy
Authors: Caliskan Ayfer , Erdem Arzum , Karadeniz Hakan 
Published: August 2009

AbstractCarboxylic acid functionalized single‐walled carbon nanotubes modified graphite sensors (SWCNT‐PGEs) were developed for electrochemical monitoring of direct DNA hybridization related to specific sequence of Hepatitis B virus, which substantially enhance the electrochemical transduction resulting from guanine oxidation signal comparison to bare PGEs. The performance characteristics of DNA hybridization on disposable CNT‐PGE were explored measuring the guanine signal in terms of optimum analytical conditions; probe and target concentration, hybridization time, and selectivity. The voltammetric results were also complemented with electrochemical impedance spectroscopy (EIS), that was used to characterize the successful construction of carbon nanotubes modification onto the surface of PGEs.