bluuebunny/crossref_metadata_2025_split huggingface dataset:
Productivity Loss Due to Presenteeism Among Patients with Arthritis: Estimates from 4 Instruments
Authors: ZHANG WEI , GIGNAC MONIQUE A.M. , BEATON DORCAS , TANG KENNETH , ANIS ASLAM H. 
Published: July 2010

Objective.To estimate and compare lost work hours attributable to presenteeism, defined as reduced productivity while working, in individuals with osteoarthritis (OA) or rheumatoid arthritis (RA), according to 4 instruments.Methods.In our prospective study, 250 workers with OA (n = 130) or RA (n = 120) were recruited from community and clinical sites. Lost hours due to presenteeism at baseline were estimated using the Health and Labor Questionnaire (HLQ), the Work Limitations Questionnaire (WLQ), the World Health Organization’s Health and Work Performance Questionnaire (HPQ), and the Work Productivity and Activity Impairment Questionnaire (WPAI). Only those respondents working over the past 2 weeks were included. Repeated-measures ANOVA was used to compare the lost-time estimates, according to each instrument.Results.Of the 212 respondents included in the analyses, the frequency of missing and “0” values among the instruments was different (17% and 61% for HLQ, 8% and 5% for WLQ, 1% and 16% for HPQ, 0% and 27% for WPAI, respectively). The average numbers of lost hours (SD) per 2 weeks due to presenteeism using HLQ, WLQ, HPQ, and WPAI were 1.6 (3.9), 4.0 (3.9), 13.5 (12.5), and 14.2 (16.7). The corresponding costs for the 2-week period were CAN$30.03, $83.05, $284.07, and $285.10. The differences in the lost-hour estimates according to instruments were significant (p < 0.001).Conclusion.Among individuals with arthritis, estimates of productivity losses while working vary widely according to the instruments chosen. Further research on instrument design and implications for a standardized approach to estimate lost time due to presenteeism is needed.
Dendritic Cell Apoptosis: Regulation of Tolerance versus Immunity
Authors: Kushwah Rahul , Hu Jim 
Published: July 2010

Abstract
Dendritic cell (DC) apoptosis is an important event that regulates the balance between tolerance and immunity through multiple pathways, and defects in DC apoptosis can trigger autoimmunity. DC apoptosis is also associated with immunosuppression and has been observed under several pathologies and infections. Recent studies indicate that apoptotic DCs can also play an active role in induction of tolerance. This review discusses the regulatory pathways of DC apoptosis, stimuli inducing DC apoptosis, and the implications of DC apoptosis in the induction of immunosuppression and/or tolerance.
Anti-TNF Therapy, from Rationale to Standard of Care: What Lessons Has It Taught Us?
Authors: Feldmann Marc , Maini Ravinder N. 
Published: July 2010

Abstract
In the mid-1980s, new molecular tools enabled the biology of cytokine expression and regulation to be studied. Our group uncovered a TNF-dependent cascade in active rheumatoid synovium, suggesting that TNF might be a therapeutic target; this concept was supported in an animal model of the disease. The proof of concept was a series of clinical trials, which have led to marked changes in the therapy of human rheumatoid arthritis and subsequently of other diseases. The work with TNF clearly demonstrated the importance of cytokines in medicine as well as the capacity of mAbs (or receptor fusion proteins) to be used long-term in large populations, thus changing the therapeutic landscape.
Indigo as a Low‐Cost Redox‐Active Sorbent for Electrochemically Mediated Carbon Capture
Authors: Jayarapu Krish N. , Mathur Anmol , Li Xing , Liu Andong , Zhang Lingyu , Kim Jaeeun , Kim Hyunah , Kuk Su Keun , Liu Yayuan 
Published: May 2024

AbstractClimate change has driven the need for carbon capture to mitigate anthropogenic greenhouse gas emissions, yet current thermochemical methods are hampered by high energy intensities. Electrochemically mediated carbon capture (EMCC) utilizing redox‐active carbon dioxide (CO2) carriers is an attractive alternative for carbon capture. Here, an economical vat dye compound, indigo, is presented, which can reversibly capture and release CO2 upon electrochemical reduction and oxidation, respectively. Electrode and electrolyte engineering strategies are utilized to improve the reversibility and stability of indigo for EMCC. A bench‐scale prototypical fixed‐bed carbon capture device is constructed to demonstrate indigo's EMCC performance under various practically relevant conditions, such as simulated flue gas and extremely dilute sources pertinent to direct air capture. A hybrid sorbent electrode‐gas diffusion layer approach is revealed to alleviate CO2 mass transport limitations, achieving ≈80% CO2 capacity utilization under a 15% CO2 feed stream. Furthermore, a reactive‐diffusive mass transport model is developed to illustrate engineering approaches that can be universally applied to optimize fixed‐bed EMCC systems. This work advances the potential for a class of low‐cost sorbents for EMCC while underscoring the importance of molecular, electrolyte, materials, and device engineering strategies to enable high‐performance carbon capture.
Smart DNA Network Capturing and Destructing Tumor‐Derived Small Extracellular Vesicles at Tumor Sites for Localized Cancer Therapy
Authors: Yang Sen , Tang Jianpu , Cheng Yu , Liu Mingxing , Lv Zhaoyue , Zhang Rui , Zhang Chunzhi , Yao Chi , Yang Dayong 
Published: May 2024

AbstractTumor‐derived small extracellular vesicles (sEVs) are proven to play important roles in accelerating the progression of tumors. Destructing the sEVs at tumor sites is therefore a promising route to inhibit tumor progression. Herein, a smart DNA network‐based sEV trap (DNET) is reported, which achieved the specific capture of tumor‐derived sEVs through recognizing sEVs by polyaptamers, and the efficient destruction of sEVs via a photodynamic process at tumor sites. The DNET is constructed through the assembly of two DNA chains generated via rolling circle amplification. The DNA chains contain polyaptamers for capturing sEVs, polyvalent G‐quadruplexes for loading photodynamic reagents, and complementary segments for forming a cross‐linked network. Upon the irradiation of the laser, the captured sEVs in DNET are destructed, causing significant inhibition effects on the migration, invasion, and proliferation of glioblastoma cells. In particular, DNET achieved tumor inhibition rates of 39.70% in the zebrafish tumor model, and 73.10% in the nude mouse tumor model, respectively, demonstrating the significant efficacy of DNET in inhibiting tumor progression.
Constructing an Asymmetric Covalent Triazine Framework to Boost the Efficiency and Selectivity of Visible‐Light‐Driven CO2 Photoreduction
Authors: Qi Guang‐Dong , Ba Dan , Zhang Yu‐Jie , Jiang Xue‐Qing , Chen Zihao , Yang Miao‐Miao , Cao Jia‐Min , Dong Wen‐Wen , Zhao Jun , Li Dong‐Sheng , Zhang Qichun 
Published: May 2024

AbstractThe photocatalytic reduction of CO2 represents an environmentally friendly and sustainable approach for generating valuable chemicals. In this study, a thiophene‐modified highly conjugated asymmetric covalent triazine framework (As‐CTF‐S) is developed for this purpose. Significantly, single‐component intramolecular energy transfer can enhance the photogenerated charge separation, leading to the efficient conversion of CO2 to CO during photocatalysis. As a result, without the need for additional photosensitizers or organic sacrificial agents, As‐CTF‐S demonstrates the highest photocatalytic ability of 353.2 µmol g−1 and achieves a selectivity of ≈99.95% within a 4 h period under visible light irradiation. This study provides molecular insights into the rational control of charge transfer pathways for high‐efficiency CO2 photoreduction using single‐component organic semiconductor catalysts.
Enabling Uniform and Accurate Control of Cycling Pressure for All‐Solid‐State Batteries
Authors: Chen Yu‐Ting , Jang Jihyun , Oh Jin An Sam , Ham So‐Yeon , Yang Hedi , Lee Dong‐Ju , Vicencio Marta , Lee Jeong Beom , Tan Darren H. S. , Chouchane Mehdi , Cronk Ashley , Song Min‐Sang , Yin Yijie , Qian Jianting , Chen Zheng , Meng Ying Shirley 
Published: May 2024

AbstractAll‐solid‐state batteries are emerging as potential successors in energy storage technologies due to their increased safety, stemming from replacing organic liquid electrolytes in conventional Li‐ion batteries with less flammable solid‐state electrolytes. However, all‐solid‐state batteries require precise control over cycling pressure to maintain effective interfacial contacts between materials. Traditional uniaxial cell holders, often used in battery research, face challenges in accommodating electrode volume changes, providing uniform pressure distribution, and maintaining consistent pressure over time. This study introduces isostatic pouch cell holders utilizing air as pressurizing media to achieve uniform and accurately regulated cycling pressure. LiNi0.8Co0.1Mn0.1O2 | Li6PS5Cl | Si pouch cells are fabricated and tested under 1 to 5 MPa pressures, revealing improved electrochemical performance with higher cycling pressures, with 2 MPa as the minimum for optimal operation. A bilayer pouch cell with a theoretical capacity of 100 mAh, cycled with an isostatic pouch cell holder, demonstrated a first‐cycle Coulombic efficiency of 76.9% and a discharge capacity of 173.6 mAh g−1 (88.1 mAh), maintaining 83.6% capacity after 100 cycles. These findings underscore the effectiveness of isostatic pouch cell holders in enhancing the performance and practical application of all‐solid‐state batteries.
Fluorophilic Sigma(σ)‐Lock Self‐Healable Copolymers
Authors: Gaikwad Samruddhi , Urban Marek W. 
Published: May 2024

AbstractAlthough F‐Containing molecules and macromolecules are often used in molecular biology to increase the binding with Lewis acidic groups by introducing favorable C−F dipoles, there is virtually no experimental evidence and limited understanding of the nature of these interactions, especially their role in synthetic polymeric materials. These studies elucidate the molecular origin of inter‐ and intra‐Chain interactions responsible for self‐healing of F‐Containing copolymers composed of pentafluorostyrene and n‐butyl acrylate units (p(PFS/nBA). Guided by dynamic surface oscillating force (SOF) and spectroscopic measurements supported by molecular dynamics (MD) simulations, these studies show that the reformation of σ‐σ orbitals in −C−F of PFS and CH3CH2− of nBA units enables the recovery of entropic energy via fluorophilic‐σ‐lock van der Waals forces when PFS/nBA molar ratios are ~50/50. The strength of these interactions determined experimentally for self‐healable PFS/nBA compositions is in the order ~0.3 kcal/mol which primarily comes from fluorophilic‐σ‐lock (~70 %) contributions. These interactions are significantly diminished for non‐self‐healable counterparts. Strongly polarized −C−F σ orbitals create lateral dipolar forces enhancing the affinity towards −C−H orbitals, facilitating energetically favorable interactions. Entropic recovery driven by non‐Covalent bonding offers a valuable tool in designing materials with unique functionalities, particularly self‐healable batteries and energy storage devices.
Ruthenium Nanoclusters and Single Atoms on α‐MoC/N‐Doped Carbon Achieves Low‐Input/Input‐Free Hydrogen Evolution via Decoupled/Coupled Hydrazine Oxidation
Authors: Li Yapeng , Niu Shuwen , Liu Peigen , Pan Rongrong , Zhang Huaikun , Ahmad Nazir , Shi Yi , Liang Xiao , Cheng Mingyu , Chen Shenghua , Du Junyi , Hu Maolin , Wang Dingsheng , Chen Wei , Li Yadong 
Published: May 2024

AbstractThe hydrazine oxidation‐assisted H2 evolution method promises low‐input and input‐free hydrogen production. However, developing high‐performance catalysts for hydrazine oxidation (HzOR) and hydrogen evolution (HER) is challenging. Here, we introduce a bifunctional electrocatalyst α‐MoC/N−C/RuNSA, merging ruthenium (Ru) nanoclusters (NCs) and single atoms (SA) into cubic α‐MoC nanoparticles‐decorated N‐doped carbon (α‐MoC/N−C) nanowires, through electrodeposition. The composite showcases exceptional activity for both HzOR and HER, requiring −80 mV and −9 mV respectively to reach 10 mA cm−2. Theoretical and experimental insights confirm the importance of two Ru species for bifunctionality: NCs enhance the conductivity, and its coexistence with SA balances the H ad/desorption for HER and facilitates the initial dehydrogenation during the HzOR. In the overall hydrazine splitting (OHzS) system, α‐MoC/N−C/RuNSA excels as both anode and cathode materials, achieving 10 mA cm−2 at just 64 mV. The zinc hydrazine (Zn−Hz) battery assembled with α‐MoC/N−C/RuNSA cathode and Zn foil anode can exhibit 97.3 % energy efficiency, as well as temporary separation of hydrogen gas during the discharge process. Therefore, integrating Zn−Hz with OHzS system enables self‐powered H2 evolution, even in hydrazine sewage. Overall, the amalgamation of NCs with SA achieves diverse catalytic activities for yielding multifold hydrogen gas through advanced cell‐integrated‐electrolyzer system.
In Situ Self‐Assembled Active and Stable Ir@MnOx/La0.7Sr0.3Cr0.9Ir0.1O3−δ Interfaces for CO2 Electrolysis
Authors: Shen Yuxiang , Wang Shuo , Li Rongtan , Lv Houfu , Li Mingrun , Ta Na , Zhang Xiaomin , Song Yuefeng , Fu Qiang , Wang Guoxiong , Bao Xinhe 
Published: May 2024

AbstractSolid oxide electrolysis cells are prospective approaches for CO2 utilization but face significant challenges due to the sluggish reaction kinetics and poor stability of the fuel electrodes. Herein, we strategically addressed the long‐standing trade‐off phenomenon between enhanced exsolution and improved structural stability via topotactic ion exchange. The surface dynamic reconstruction of the MnOx/La0.7Sr0.3Cr0.9Ir0.1O3−δ (LSCIr) catalyst was visualized at the atomic scale. Compared with the Ir@LSCIr interface, the in situ self‐assembled Ir@MnOx/LSCIr interface exhibited greater CO2 activation and easily removable carbonate intermediates, thus reached a 42 % improvement in CO2 electrolysis performance at 1.6 V. Furthermore, an improved CO2 electrolysis stability was achieved due to the uniformly wrapped MnOx shell of the Ir@MnOx/LSCIr cathode. Our approach enables a detailed understanding of the dynamic microstructure evolution at active interfaces and provides a roadmap for the rational design and evaluation of efficient metal/oxide catalysts for CO2 electrolysis.
Interfacial Super‐Assembly of Vacancy Engineered Ultrathin‐Nanosheets Toward Nanochannels for Smart Ion Transport and Salinity Gradient Power Conversion
Authors: Awati Abuduheiremu , Yang Ran , Shi Ting , Zhou Shan , Zhang Xin , Zeng Hui , Lv Yaokang , Liang Kang , Xie Lei , Zhu Dazhang , Liu Mingxian , Kong Biao 
Published: May 2024

AbstractIon‐selective nanochannel membranes assembled from two‐dimensional (2D) nanosheets hold immense promise for power conversion using salinity gradient. However, they face challenges stemming from insufficient surface charge density, which impairs both permselectivity and durability. Herein, we present a novel vacancy‐engineered, oxygen‐deficient NiCo layered double hydroxide (NiCoLDH)/cellulose nanofibers‐wrapped carbon nanotubes (VOLDH/CNF‐CNT) composite membrane. This membrane, featuring abundant angstrom‐scale, cation‐selective nanochannels, is designed and fabricated through a synergistic combination of vacancy engineering and interfacial super‐assembly. The composite membrane shows interlayer free‐spacing of ~3.62 Å, which validates the membrane size exclusion selectivity. This strategy, validated by DFT calculations and experimental data, improves hydrophilicity and surface charge density, leading to the strong interaction with K+ ions to benefit the low ion transport resistance and exceptional charge selectivity. When employed in an artificial river water|seawater salinity gradient power generator, it delivers a high‐power density of 5.35 W/m2 with long‐term durability (20,000s), which is almost 400 % higher than that of the pristine NiCoLDH membrane. Furthermore, it displays both pH‐ and temperature‐sensitive ion transport behavior, offering additional opportunities for optimization. This work establishes a basis for high‐performance salinity gradient power conversion and underscores the potential of vacancy engineering and super‐assembly in customizing 2D nanomaterials for diverse advanced nanofluidic energy devices.
The influence of in situ microfibrillation on the mechanical properties and warpage of low‐density polyethylene/polystyrene composite prepared by fused filament fabrication
Authors: Wang Peng bo , Yang Tao , Hu Jie wei , Zhang Jie 
Published: May 2024

AbstractFused filament fabrication (FFF) has been widely adopted due to its simplicity and cost‐effectiveness. But until now, its application materials are still limited. Polyolefin material is one of the most commonly used plastics. However, low‐density polyethylene (LDPE) is rarely used in FFF due to the inadequate strength of the filaments and the warpage of the printed parts. In this work, polystyrene (PS) is added to LDPE to obtain blend filaments. After that, the filaments are used to validate the possibility of in situ microfibrillation directly in the process. The results show that the addition of PS can significantly improve the bending strength, bending modulus, and hardness without affecting the heat resistance and crystal transition of the composite. Besides, the PS dispersed phase can form microfibers under the influence of the shear field. The formation of microfibers can significantly enhance the mechanical properties of composites. The tensile strength and Young's modulus increase by 140% and 221%, respectively. The warping deformation and surface morphology of printed parts are also improved. This study provides a new idea for utilizing low‐strength polyolefin in 3D printing and achieving performance enhancement.
Practice what you preach: Does the legal status of microfinance institutions matter in gender equality?
Authors: Mia Md Aslam , Soeparna Intan Inayatun , Dalla Pellegrina Lucia 
Published: May 2024

AbstractConsidering the importance of promoting gender equality, Microfinance Institutions (MFIs) have emerged to reduce the gender gap by supplying credit opportunities to women. However, the microfinance literature has largely focused on the role of women in the client base while devoting less attention to their representation in the organizational structure of MFIs. This study aims to fill this gap. Using ANOVA and random effects models, our purpose is to investigate which types of MFIs more intensively promote gender equality within their workforce, at any of the organizational ladders. We analyze data from 1222 MFIs across 102 developing countries from 2010 to 2018. Empirical evidence reveals that the presence of females in both the workforce and the client base is significantly lower in commercially motivated MFIs (e.g., banks and other for‐profit institutions) compared to non‐government organizations (NGOs), and —to a lesser extent— credit unions, cooperatives and rural banks. Our results suggest that the microfinance sector would benefit from a stronger emphasis on NGO‐driven initiatives to promote female representation in terms of both employment opportunities and access to credit.
Volatile Profiles and DNA Barcodes of Myrtaceae Species with Occurrence in the Brazilian Amazon
Authors: dos Santos Edimara L. , Xavier Júlia Karla A. M. , Galvão Paula Luely N. , Carneiro Nunes Adriana R. , Alegria Oscar Victor C. , Moreira Edith Cibelle O. , Maia José Guilherme S. , Setzer William N. , Figueiredo Pablo Luis B. , da Silva Joyce Kelly R. 
Published: May 2024

AbstractMyrtaceae family includes many species with taxonomic challenges, making it one of the most complex families to identify. This study used DNA barcoding to find molecular markers for species authentication based on the Myrtaceae family‘s chemical composition and genetic diversity. Essential oils and genetic material were extracted from the leaves of six different species: Eugenia uniflora, E. patrisii, Myrcia splendens, Psidium guajava, P. guineense, and Psidium sp. The samples were analyzed based on compound classes and grouped into two categories. Group I included samples with high amounts of oxygenated sesquiterpenes (3.69–76.05 %) and fatty acid derivatives (0.04–43.59 %), such as E. uniflora, Myrcia splendens, and E. patrisii. Group II included samples P. guajava, P. guineense, and Psidium sp., which had a significant content of monoterpene hydrocarbons (0.69–72.35 %), oxygenated sesquiterpenes (8.06–68.1 %), phenylpropanoids (0.45–22.59 %), and sesquiterpene hydrocarbons (0.27–21.84 %). The PsbA‐trnH gene sequences had a high genetic variability, allowing the species to be distinguished. A phylogenetic analysis showed two main clusters with high Bootstrap values corresponding to the subtribes Eugeniineae, Myrciinae, and Pimentinae. The results suggest a weak correlation between genetic and chemical data in these Myrtaceae species.
Keplerate‐Type Polyoxometalates‐Based Triboelectric Nanogenerator for Higher Performance via the Morphology Modulation of Blackberry Structure
Authors: Du Wei , Hao Yijia , He Yi , Chen Yan , Peng Yi , Chen Weilin 
Published: May 2024

AbstractThe tribe‐material is the key factor affecting the performance of triboelectric nanogenerators (TENGs). Inorganic materials have higher heat resistance and stability than widely used organic materials. However, the weaker tribe‐property limits the application of TENGs. Modulating surface roughness by changing particle shape and size is a simple way to increase performance for TENGs. Polyoxometalates (POMs) have unrivalled structural diversity and can self‐assemble to form different nanostructures. In this study, we propose [{(NH4)42[Mo72VIMo60VO372(CH3COO)30 (H2O)72] ⋅ ca.300H2O ⋅ ca.CH3COONH4)}‐Mo132] and [{Na8K14(VO)2[{(MoVI) (Mo5VIO21)(H2O)3]}10{(MoVI)Mo5VIO21(H2O)3 (SO4)}2{VIVO(H2O)20} {VIVO}10({KSO4}5)2] ⋅ 150H2O)}‐Mo72V30] with blackberry structure which are cured and prepared into film by spin‐coating technique, are used as positive tribe‐materials for the first time in the field of TENGs. Keplerate‐type POMs can form blackberry structures with higher dispersibility and flexibility, which can be used to control surface roughness by regulating the size of particles. The discovery proves that the particle size influences the surface roughness, which adjusts the output of TENGs. According to our findings, Mo132‐h‐TENG generates an output voltage of 29.3 V, an output charge of 8 Nc, which is 2–3 folds higher than Mo132‐TENG, and a maximum power density of 6.25 mW ⋅ m−2 at 300 MΩ. Our research provides that altering the dimensional size can be an available way to raise the output of TENGs.
Fluorination/Dearomatization of C6F5 Groups: An FLP Route to an Electrophilic Borane and Non‐Coordinating Anions
Authors: Kim Hyehwang , Mandal Dipendu , Ng Joshua Kye Jin , Qu Zheng‐Wang , Grimme Stefan , Stephan Douglas W. 
Published: May 2024

AbstractB(C6F5)3 and the corresponding anion [B(C6F5)4]− are ubiquitous in main group and transition metal chemistry. Known derivatives are generally limited to the incorporation of electron donating substituents. Herein we describe electrophilic fluorination and dearomatization of such species using XeF2 in the presence of BF3 or Lewis acidic cations. In this fashion the anions [HB(C6F5)3]−, [B(C6F5)4]− and [(C6F5)3BC≡NB(C6F5)3]−, are converted to [FB(C6F7)3]−, [B(C6F7)4]−, and [(C6F7)3BC≡NB(C6F7)3]−, respectively. Similarly, the borane adducts (L)B(C6F7)3 (L=MeCN, OPEt3) are produced. These rare examples of electrophilic attack of electron deficient rings proceed as [XeF][BF4] acts as a frustrated Lewis pair effecting fluorination and dearomatization of C6F5 rings.