bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polish artificial heart program
Authors: El Fray Miroslawa , Czugala Monika 
Published: November 2011

AbstractDespite significant advances in the development of artificial heart substitutes, anthrombogenic materials and surfaces remain to be the main challenge for implants, which can prevent thrombosis that leads to rejection. The goal of material engineering is essentially to design polymeric materials of high durability and optimal thrombogenicity in mechanical heart prosthesis, being developed recently in a frame of the polish artificial heart program. For these reasons, various surface modifications are being continuously developed for a ‘gold standard’ material, which is a polyurethane (PU) thermoplastic elastomer and they will be shortly reviewed. However, new polymeric materials can meet medical word's attention if they are able to provide similar or better characteristics in term of bulk and surface properties. Specifically, if they will show appropriate surface topography, which is the most influential in determining the response of live tissues toward biomaterials. Nanostructured polyester thermoplastic elastomers of high biodurability as an alternative to PU materials for artificial heart are challenging new materials, and they will be discussed briefly.WIREs Nanomed Nanobiotechnol2012, 4:322–328. doi: 10.1002/wnan.175This article is categorized under:Implantable Materials and Surgical Technologies > Nanomaterials and ImplantsImplantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement
Mixed Micellization Behavior of m‐2‐m Gemini Surfactants with Some Conventional Surfactants at Different Temperatures
Authors: Sood Ashwani K. , Singh Kultar , Kaur Jasbir , Banipal Tarlok S. 
Published: November 2011

AbstractMixed micellization behavior of dimeric cationic surfactants ethanediyl‐1,2‐bis(dimethyl alkyl ammonium bromide) (m‐2‐m where m = 10, 12) with conventional single chain cationic surfactants like cetyltrimethyl ammonium bromide (CTAB), cetylpyridinium chloride (CPC), tetradecyl dimethyl benzyl ammonium chloride (C14BCl) and cetyl dimethyl benzyl ammonium chloride (C16BCl) were studied in aqueous and aqueous polyethylene glycol (PEG) solutions at 298.15, 308.15 and 318.15 K respectively using conductometric and viscometric methods. In aqueous solutions, all the combinations (except 12‐2‐12 + CTAB) were found to behave nonideally with mutual synergism which decreases with increase in temperature. Various thermodynamic parameters of micellization like , and were evaluated and discussed. Similarly in presence of PEG, the thermodynamic properties like , and associated with the transfer of surfactant monomers from the medium consisting of polymer‐free mixed micelles to polymer‐bound mixed micelles at various temperatures were also calculated. The negative values of show that aggregation process is more exothermic than micellization whereas the negative values of indicate that the presence of polymer bound mixed micelles decreases the degree of randomness of the system. Viscosity studies show that in aqueous solutions all the combinations of 10‐2‐10/12‐2‐12 display negative departure in the relative viscosity (ηr) from additivity rule which decreases with increase in temperature. Similarly in the presence of 5% PEG solutions the magnitude of the negative departure decreases for all the combinations and becomes positive in the case of C14BCl and CPC combinations with the studied gemini surfactants at higher temperatures.
Wie groß sind die kleinen genetischen Risiken?
Authors: Heid I.M. , Winkler T.W. , Grassmann F. , Weber B.H.F. 
Published: November 2011

Zusammenfassung
Während Familienstudien sich als sehr geeignet zeigen, um starke genetische Risikovarianten aufzuspüren, sind genomweite Assoziationsstudien mit nichtverwandten Personen besonders effizient in der Identifizierung von moderaten und schwachen genetischen Risiken bei multifaktoriellen Erkrankungen und erkrankungsrelevanten quantitativen Parametern. Hier wird dargestellt, wie das genetische Risiko für solch moderat bis schwach wirkende Varianten berechnet wird. An den Beispielen Adipositas, Diabetes und altersbedingte Makuladegeneration wird gezeigt, welche Modelle Anwendung finden und wie groß diese „kleinen“ genetischen Risiken sind.
Tectonics of Proterozoic Cuddapah Basin, Southern India: A Conceptual Model
Authors: Chetty T. R. K. 
Published: November 2011

Abstract
A tectonic map of Cuddapah Basin (CB) and its adjacent regions has been compiled using LANDSAT TM data and the available literature on the prominent tectonic features which include Archaean greenstone belts, disposition of Proterozoic mobile belts along with the associated mid-crustal shear zones, and the mafic dyke swarms. The field characteristics of the two major fault zones: Gudur-Cuddapah and the Veldurti-Kalva-Gani fault system that cut across the CB have been re-examined and are re-interpreted as typical of transfer faults, which are generated exclusively by extensional tectonics. The earlier concept that these fault systems form a conjugate set of “Anderson type” causing the `Cuddapah salient’, needs to be reviewed.
The widespread extension in the upper crust is manifest in the form of normal faulting of ‘listric’ type in the Papaghni basin and a ‘domino’ type in the Nallamalai basin. While extensional tectonics have played a major role in shaping the geometry and kinematics of CB, the intermittent phases of compression seem to have been derived from major shearing events related to Proterozoic collisional processes in the region. A hypothetical crustal-cross section across the CB has been constructed considering the available geological and geophysical data and analogies were drawn from well-studied sedimentary basins of other continents. The presence of low- dipping detachment faults and shear zones in the lower crust, and their possible linkage with the extensional faults in the upper crust have been inferred to explain the evolution of the CB. The fault patterns and kinematic history in conjunction with the crustal architecture strongly suggest that the evolution of CB is genetically related to the Proterozoic collisional processes and associated crustal-scale transpressional tectonics in the basement at the eastern margin.
Posttraumatic stress disorder at the end of life: Extant research and proposed psychosocial treatment approach
Authors: Feldman David B. 
Published: November 2011

AbstractAccording to some estimates, 84% of people experience a traumatic event during their lives (Vrana & Lauterbach, 1994), and 15% to 24% then develop posttraumatic stress disorder (PTSD). Many carry with them lasting effects of trauma as they age and enter the last phase of life. PTSD manifests in unique ways at the end of life, possibly disrupting factors associated with a positive dying process, including social support, medical communication, life review, and acceptance of death. Terminally ill people with PTSD may suffer more emotional distress, lower quality of life, and poorer medical prognosis than those without PTSD. Unfortunately, healthcare providers may not be trained to address this issue. This article reviews the literature concerning how PTSD may affect the end of life and proposes an intervention model based on a palliative care philosophy.
Magnetoresistance in FeCoZr–Al2O3 nanocomposite films containing ‘metal core–oxide shell’ nanogranules
Authors: Fedotova J A , Przewoznik J , Kapusta Cz , Milosavljević M , Kasiuk J V , Zukrowski J , Sikora M , Maximenko A A , Szepietowska D , Homewood K P 
Published: November 2011

Abstract
Temperature and magnetic field dependences of electrical conductivity are systematically studied in granular films (Fe45Co45Zr10)
x
(Al2O3)100−x
(28 ⩽ x ⩽ 64) containing crystalline metallic α-FeCo-based nanoalloy cores encapsulated in an amorphous oxide shell embedded in an amorphous Al2O3 matrix. Formation of ‘metallic core–oxide shell’ nanogranules is confirmed by transmission electron microscopy (TEM) and HRTEM. The structure of core and shell is governed with the difference in the oxidation states of Fe and Co ions investigated with EXAFS, XANES and Mössbauer spectroscopy. A considerable negative magnetoresistance (MR) effect of spin-dependent nature is observed in the whole range of x values. Its increase with decreasing temperature is correlated with the magnetic saturation of superparamagnetic metallic nanogranules. The enhanced MR effect in ‘core–shell’ granular films is related to the percolation of oxide shells and their influence through spin filtering processes. A considerable high field MR at low temperatures and the resulting deviation of MR and squared magnetization are attributed to a magnetic randomness and/or strong magnetic anisotropy of the magnetic oxide shell.
Integrating human and murine anatomical gene expression data for improved comparisons
Authors: Jiménez-Lozano Natalia , Segura Joan , Macías José Ramón , Vega Juanjo , Carazo José María 
Published: November 2011

Abstract
Motivation: Information concerning the gene expression pattern in four dimensions (species, genes, anatomy and developmental stage) is crucial for unraveling the roles of genes through time. There are a variety of anatomical gene expression databases, but extracting information from them can be hampered by their diversity and heterogeneity.
Results: aGEM 3.1 (anatomic Gene Expression Mapping) addresses the issues of diversity and heterogeneity of anatomical gene expression databases by integrating six mouse gene expression resources (EMAGE, GXD, GENSAT, Allen Brain Atlas data base, EUREXPRESS and BioGPS) and three human gene expression databases (HUDSEN, Human Protein Atlas and BioGPS). Furthermore, aGEM 3.1 provides new cross analysis tools to bridge these resources.
Availability and implementation: aGEM 3.1 can be queried using gene and anatomical structure. Output information is presented in a friendly format, allowing the user to display expression maps and correlation matrices for a gene or structure during development. An in-depth study of a specific developmental stage is also possible using heatmaps that relate gene expression with anatomical components. http://agem.cnb.csic.es
Contact: natalia@cnb.csic.es
Supplementary information: Supplementary data are available at Bioinformatics online.
Identification of context-specific gene regulatory networks with GEMULA—gene expression modeling using LAsso
Authors: Geeven Geert , van Kesteren Ronald E. , Smit August B. , de Gunst Mathisca C. M. 
Published: November 2011

Abstract
Motivation: Gene regulatory networks, in which edges between nodes describe interactions between transcriptional regulators and their target genes, determine the coordinated spatiotemporal expression of genes. Especially in higher organisms, context-specific combinatorial regulation by transcription factors (TFs) is believed to determine cellular states and fates. TF–target gene interactions can be studied using high-throughput techniques such as ChIP-chip or ChIP-Seq. These experiments are time and cost intensive, and further limited by, for instance, availability of high affinity TF antibodies. Hence, there is a practical need for methods that can predict TF–TF and TF–target gene interactions in silico, i.e. from gene expression and DNA sequence data alone. We propose GEMULA, a novel approach based on linear models to predict TF–gene expression associations and TF–TF interactions from experimental data. GEMULA is based on linear models, fast and considers a wide range of biologically plausible models that describe gene expression data as a function of predicted TF binding to gene promoters.
Results: We show that models inferred with GEMULA are able to explain roughly 70% of the observed variation in gene expression in the yeast heat shock response. The functional relevance of the inferred TF–TF interactions in these models are validated by different sources of independent experimental evidence. We also have applied GEMULA to an in vitro model of neuronal outgrowth. Our findings confirm existing knowledge on gene regulatory interactions underlying neuronal outgrowth, but importantly also generate new insights into the temporal dynamics of this gene regulatory network that can now be addressed experimentally.
Availability: The GEMULAR-package is available from http://www.few.vu.nl/~degunst/gemula_1.0.tar.gz.
Contact: g.geeven@hubrecht.eu
Supplementary information: Supplementary data are available at Bioinformatics online.
Advice under uncertainty in the marine system
Authors: Dankel Dorothy J. , Aps Robert , Padda Gurpreet , Röckmann Christine , van der Sluijs Jeroen P. , Wilson Douglas C. , Degnbol Poul 
Published: November 2011

Abstract
Dankel, D. J., Aps, R., Padda, G., Röckmann, C., van der Sluijs, J. P., Wilson, D. C., and Degnbol, P. 2012. Advice under uncertainty in the marine system. – ICES Journal of Marine Science, 69: 3–7. There is some uncertainty in the fisheries science–policy interface. Although progress has been made towards more transparency and participation in fisheries science in ICES Areas, routine use of state-of-the-art quantitative and qualitative tools to address uncertainty systematically is still lacking. Fisheries science that gives advice to policy-making is plagued by uncertainties; the stakes of the policies are high and value-laden and need therefore to be treated as an example of “post-normal science” (PNS). To achieve robust governance, understanding of the characteristics and implications of the scientific uncertainties for management strategies need to come to the centre of the table. This can be achieved using state-of-the-art tools such as pedigree matrices and uncertainty matrices, as developed by PNS scholars and used in similar science–policy arenas on other complex issues. An explicit extension of the peer community within maritime systems will be required to put these new tools in place. These new competences become even more important as many countries within the ICES Area are now embarking on new policies.
Characterisation of odour‐active compounds in papaya (Carica papaya L.) wine
Authors: Pino Jorge A. , Queris Oscar 
Published: November 2011

SummaryThe volatile compounds of papaya wine were isolated by continuous solvent extraction and analysed by gas chromatography‐flame ionization detector and gas chromatography‐mass spectrometry. A total of 118 volatile constituents were detected, and ninety‐seven were positively identified. The composition of papaya wine included fifty‐three esters, twenty‐two alcohols, nine acids, seven phenols and derivatives, seven sulphur compounds, five lactones, five terpenes, three ketones, two aldehydes and five miscellaneous compounds. The aroma‐active areas in the gas chromatogram were screened by application of the aroma extract dilution analysis and by odour activity values. Six odorants were considered as odour‐active volatiles: ethyl octanoate, (E)‐β‐damascenone, 3‐methylbutyl acetate, benzyl isohtiocyanate; ethyl hexanoate and ethyl butanoate.
Evaluation of antioxidant activity of muscle and skin protein hydrolysates from giant kingfish, Caranx ignobilis (Forsskål, 1775)
Authors: Nazeer R. A. , Anila Kulandai K. 
Published: November 2011

SummaryTo assess the antioxidant properties of fish protein hydrolysate from giant kingfish Caranx ignobilis (Forsskål, 1775), muscle and skin were obtained using various proteases (papain, pepsin, trypsin and α‐chymotrypsin), respectively. Antioxidant activities of the resulting hydrolysates were evaluated using 2, 2‐diphenyl‐1‐picrylhydrazyl radical scavenging activity, reducing power and metal chelating activity. Among the hydrolysates, peptic of muscle (37 ± 1.0; 0.290 ± 0.012; 63.30 ± 0.57) and tryptic of skin (36.2 ± 1.0; 0.190 ± 0.110; 63 ± 0.57) hydrolysates, which had the highest free radical scavenging activity, was subjected to purification using Sephadex G‐25. The fractionated hydrolysates were superior to the original hydrolysates in the antioxidative activity tested. The active fractions (MF2 and SF2) effectively inhibited lipid peroxidation in linoleic acid emulsion system, and the activity was compared with α‐tocopherol. The amino acid profile of MF2 and SF2 showed a high level of essential amino acids, and the most abundant amino acids were in the order His (12.01% and 7.08%), Phe (7.05% and 6.18%) and Lys (6.76% and 4.74%). Conclusively, C. ignobilis muscle and skin hydrolysates could be a promising rich source of natural antioxidants.
Effects of pretreatment and various operating parameters on permeate flux and quality during ultrafiltration of apple juice
Authors: Bahçeci K. Savaş 
Published: November 2011

SummaryThe central composite design with a quadratic model was used to investigate the effect of temperature (20–40 °C) and transmembrane pressure (TMP) (100–300 kPa) as well as pretreatment with gelatin and bentonite (0:0–300:1500 mg L−1) on permeate flux and fouling resistance during ultrafiltration of apple juice. The changes in some physicochemical properties were also investigated. Pretreatment of apple juice with gelatin and bentonite and an increase in the temperature and TMP significantly improved the permeate flux. In general, physicochemical properties of apple juice other than polyphenolics were not affected by the applied parameters. Using 150 mg L−1 of gelatin and 750 mg L−1 of bentonite for fining significantly reduced the total phenolic content and so did the fouling resistance. Fouling resistance also decreased with increasing temperature, and increasing pressure increased the fouling resistance.
Protein content determination in Brassica oleracea species using FT‐NIR technique and PLS regression
Authors: Szigedi Tamás , Lénárt József , Dernovics Mihály , Turza Sándor , Fodor Marietta 
Published: November 2011

SummarySix fresh and one frozen vegetable cultivar groups possessing remarkably different morphology from the same Brassica oleracea species, including broccoli, Brussels sprouts, curly cabbage, white cabbage, red cabbage, cauliflower and white kohlrabi, were chosen to set up a Fourier transform near‐infrared spectroscopy (FT‐NIR)‐based method for the quantification of protein content. Sample preparation was based on lyophilisation and homogenisation. Calibration was set up with the help of the Kjeldahl method for the quantification of protein content in the range of 12.9–32.5 m/m%. Calibration model was developed using the spectral regions 1136–1334 and 1639–1836 nm, with partial least squares regression. This model was checked by cross‐validation. The performance of the final FT‐NIR estimation model was evaluated by root mean square of cross‐validation, root‐mean‐square error of estimation and the determination coefficient (R2). The final estimation function for the protein determination was characterised with the predictive error of 0.76 m/m% and R2 value of 98.81.
Derivation, Characterization and Differentiation of Buffalo (Bubalus bubalis) Amniotic Fluid Derived Stem Cells
Authors: Dev K , Giri SK , Kumar A , Yadav A , Singh B , Gautam SK 
Published: November 2011

ContentsAmniotic fluid cells (AFCs) are obtained from amnion for pre‐natal analysis and can be cultured in vitro. Heterogeneous amniotic fluid (AF) contains various cell types, and it is believed that some of these cells possess the stem cell properties. The aim of this study was to characterize these cells by phenotypical and genotypical means in buffalo. The differentiation potential of amniotic fluid stem (AFS) cells was carried out by converting these cells into neurons. The AFCs were cultured without feeder cells in DMEM containing 16% foetal bovine serum, 1% penicillin/streptomycin and 1%l‐glutamine in 5% CO2 at 38.5 ± 0.5°C in a CO2 incubator. After 6 days of culture, different types of cells viz., star shaped (62.7%), spherical without nucleus (1.9%), spherical with nucleus (26.4%), pentagonal (0.4%) and free floating/rounded cells (8.3%) were observed. Most of the cells started anchorage‐dependent growth after day 7 of the culture. Expression of Oct‐4, Sox‐2, Nanog, alkaline phosphatase, 18s rRNA, stem cell factor, cyclin A, Nestin and FGF‐5 was observed from the AFS cells in different passages with PCR amplicon of 314, 277, 317, 180, 162, 216, 421, 307 and 210 bp, respectively. During the differentiation step, at day 6, neuron‐like cells could be clearly identified and confirmed with Nestin‐specific RT‐PCR. The cells were found to have a normal karyotype at different passages. These results may contribute towards establishing non‐embryonic pluripotent stem cells for various therapeutic and reproductive biotechnological applications in the species.
Understanding overweight adolescents' beliefs using the theory of planned behaviour
Authors: Rhoades Debra R , Al‐Oballi Kridli Suha , Penprase Barbara 
Published: November 2011

Rhoades DR, Al‐Oballi Kridli S, Penprase B. International Journal of Nursing Practice 2011; 17: 562–570Understanding overweight adolescents' beliefs using the theory of planned behaviourThis qualitative inquiry examined adolescents' experiences surrounding their beliefs towards being overweight. The purpose of this qualitative study was to understand behavioural, normative and control beliefs of overweight adolescents regarding losing weight, exercising and eating healthy. Purposive sampling was used to obtain 10 overweight adolescents between the ages of 13 and 19. The theory of planned behaviour was used as a theoretical framework for this study. An interview guide based on the Theory of Planned was used to conduct individual semistructured interviews. Content analysis showed that overweight adolescents exhibited positive attitudes in dealing with their weight status and valued their family's support and guidance in helping control their weight. Although friends were important to facilitate regular exercise, families, particularly mothers, were crucial in addressing healthy eating habits. Understanding the subtleties and complexities of living with childhood overweight might assist health professionals in creating more effective and developmentally sensitive interventions.
Protecting and respecting military nurses
Authors: Rushton Patricia 
Published: November 2011

Rushton P. International Journal of Nursing Practice 2011; 17: 615–620Protecting and respecting military nursesThere are data reported in psychological and sociological scientific literature concerning the physical and sexual abuse of members of the US Military Services with a focus on abuse of females. An extensive search of that literature found little evidence that military nurses had experienced physical or sexual abuse. An oral history project to collect accounts of wartime experiences of military nurses is currently ongoing from an institution in the western United States. A secondary analysis of data finds that project participants included almost no reports of such abuse. Rather, there were many reports that nurses were respected and protected from harm during the time of their military service.