bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A Copper(II)‐Mediated Regioselective Cyclization—Acetoxylation of 6,8‐Dien‐1‐ones for the Synthesis of Functionalized Cyclopentanes.
Authors: Wang Yazhou , Du Haifeng 
Published: September 2010

AbstractIn the presence of Cu(O‐Ac)2 and NaOAc, 6,8‐dien‐1‐ones undergo regio‐ and stereoselective cyclization—acetoxylation.
ChemInform Abstract: Reductive Amination Using Ammonia Borane.
Authors: Ramachandran P. Veeraraghavan , Gagare Pravin D. , Sakavuyi Kaumba , Clark Paul 
Published: September 2010

AbstractThe reaction of aldehydes and ketones with primary and secondary amines under conditions A) and B) affords secondary and tertiary amine products in excellent yields.
ChemInform Abstract: 4‐Hydroxy‐2′‐nitrodiphenyl Ether Analogues as Novel Tyrosinase Inhibitors.
Authors: Sapkota Kiran , Lee Eunyoung , Yang Jae‐Ho , Kwon Youngjoo , Choi Jongwon , Na Younghwa 
Published: September 2010

AbstractA series of hydroxy‐ and nitro‐substituted diphenyl ethers are prepared as novel tyrosinase inhibitors.
ChemInform Abstract: Synthesis of Substituted N‐[3‐(3‐Methoxyphenyl)propyl] Amides as Highly Potent MT2‐Selective Melatonin Ligands.
Authors: Hu Yueqing , Ho Maurice K. C. , Chan King H. , New David C. , Wong Yung H. 
Published: September 2010

AbstractThe title compounds (I) are screened for their binding affinities towards human melatonin MT1 and MT2 receptors.
ChemInform Abstract: Direct Metal‐Free α‐Iodination of Arylketones Induced by Iodine or Iodomethane with HTIB in Ionic Liquid.
Authors: Lee Jong Chan , Kim Jimi , Park Hyun Jung , Kwag Byungmook , Lee Seung Bae 
Published: September 2010

AbstractPhI(OH)‐O‐Tos (HTIB) is shown to promote the α‐iodination of ketones in [bmim]BF4.
ChemInform Abstract: Diastereoselective Synthesis of Tetrahydrofurans from Aryl 3‐Chloropropylsulfoxides and Aldehydes.
Authors: Komsta Zofia , Barbasiewicz Michal , Makosza Mieczyslaw 
Published: September 2010

AbstractSulfoxides of type (I) smoothly react with electron‐rich nonenolizable aldehydes to afford trans‐substituted tetrahydrofurans with high stereoselectivity.
ChemInform Abstract: Regioselective Synthesis of 3‐Indolyl(alkoxy)acetates.
Authors: Suarez‐Castillo Oscar R. , Melendez‐Rodriguez Myriam , Cano‐Escudero Indira C. , Luz De Ita‐Gutierrez Sandra , Sanchez‐Zavala Maricruz , Morales‐Rios Martha S. , Joseph‐Nathan Pedro 
Published: September 2010

Abstract(Z)‐ and (E)‐2‐alkoxyindolenines (V) and (VI) are synthesized by treating bromoindole (II) with alcohols in the presence of molecular sieves.
ChemInform Abstract: Copper‐Mediated Cyclization—Halogenation and Cyclization—Cyanation Reactions of β‐Hydroxyalkynes and o‐Alkynylphenols and Anilines.
Authors: Swamy Nalivela Kumara , Yazici Arife , Pyne Stephen G. 
Published: September 2010

AbstractThe reactions allow a new and direct access to functionalized furopyrroles, benzofurans, and indoles.
ChemInform Abstract: Synthesis, Spectral and Antimicrobial Studies of Some N(2)‐Substituted Tetrahydroindazoles.
Authors: Amirthaganesan Shanmugasundaram , Aridoss Gopalakrishnan , Park Keun Soo , Lim Kwon Taek , Jeong Yeon Tae 
Published: September 2010

Abstract2 series of 9 title compounds each of type (III) and (IV) are prepared and tested for their antimicrobial activities.
ChemInform Abstract: Imidazo[1,2]hetarylglyoxylates: Synthesis and Reactivity Toward Nucleophiles.
Authors: Zamkova Irina A. , Chekotylo Oleksiy O. , Geraschenko Oleksandr V. , Grygorenko Oleksandr O. , Mykhailiuk Pavel K. , Tolmachev Andrey A. 
Published: September 2010

AbstractThe title compounds are synthesized via Friedel—Crafts acylation of fused imidazoles with ethyl oxalyl chloride.
ChemInform Abstract: Construction of Linked Nitrogen Heterocycles by Palladium(0)‐Catalyzed Intramolecular Domino Cyclization of 2‐Alkynylaziridines Bearing a 2‐Aminoethyl Group via Ring Expansion with Isocyanate.
Authors: Okano Akinori , Oishi Shinya , Tanaka Tetsuaki , Fujii Nobutaka , Ohno Hiroaki 
Published: September 2010

AbstractThe Pd‐catalyzed reaction of alkynylaziridines of type (I) and (V) with isocyanates provides a new approach to pyrrolinylimidazolidinones and/or imidazolidinyldiazepinones depending on the nature of substituents and conditions used.
ChemInform Abstract: Exploration of Amino Alcohol Derivatives as Novel, Potent, and Highly Selective Sphingosine‐1‐phosphate Receptor Subtype‐1 Agonists.
Authors: Evindar Ghotas , et al. et al. 
Published: September 2010

AbstractPPI‐4955 ((R)‐I) is found to be a potent and selective preclinical candidate with an excellent in vivo potency and dose responsiveness and markedly improved overall in vivo pharmacodynamic properties upon oral administration.
ChemInform Abstract: Synthesis of Benzoxazole Amides as Novel Antifungal Agents Against Malassezia furfur.
Authors: Kim Beom Joon , Kim Jinah , Kim Young‐Kook , Choi Soon‐Yong , Choo Hea‐Young Park 
Published: September 2010

AbstractA series of 12 benzoxazole amides (VI) are prepared and tested as antifungal agents against Malassezia furfur.
ChemInform Abstract: Synthesis of Perfluorinated Heterocyclic Compounds Having a Long Alkyl Chain Functionality by 1,3‐Dipolar Cycloaddition.
Authors: Lee Chan Woo , Hwang Ho Yun , Park Joo Yuen , Chi Ki‐Whan 
Published: September 2010

AbstractPerfluorinated compounds having a long alkyl‐chain functionality are prepared by 1,3‐dipolar cycloaddition reactions with 1,3‐dipoles (in situ‐formed NH‐nitrones or nitrile oxides).
ChemInform Abstract: Synthesis of 2,6‐Bis(fluoroalkyl) ‐2,6‐dihydroxytetrahydro‐2H‐pyran‐3,5‐dicarboxylates from Aldehydes and Fluorinated β‐Oxo Esters in the Presence of Ionic Liquid—K2CO3 as Catalytic System.
Authors: Zlotin S. G. , Kryshtal G. V. , Zhdankina G. M. , Ignatenko A. V. , Burgart Ya. V. , Saloutin V. I. , Chupakhin O. N. 
Published: September 2010

AbstractThe catalytic system retains its catalytic activity for three reaction cycles.
ChemInform Abstract: Facile Synthesis of 9‐Acetyl/Formyl/Cyano‐substituted Pyrano[2,3‐f]flavones and Chromones Using the Baylis—Hillman Reaction.
Authors: Reddy S. Satyanarayana , Krupadanam G. L. David 
Published: September 2010

AbstractNovel flavones / chromones (III) with a pyran ring fused at 7,8‐position are synthesized starting from the corresponding 8‐formyl‐7‐hydroxy derivatives via Baylis‐Hillman reaction.
ChemInform Abstract: Synthesis and Reactions of Some Novel Nicotinonitrile, Thiazolotriazole, and Imidazolotriazole Derivatives for Antioxidant Evaluation.
Authors: Sayed Hayam H. , Morsy Eman M. H. , Flefel Eman M. 
Published: September 2010

AbstractNovel 2‐O‐substituted pyridine derivatives are synthesized and tested for their free radical scavenging capacity in DPPH assay.
ChemInform Abstract: A One‐Step Synthesis of 2,4‐Unsubstituted Quinoline‐3‐carboxylic Acid Esters from o‐Nitrobenzaldehydes.
Authors: Venkatesan Hariharan , Hocutt Frances M. , Jones Todd K. , Rabinowitz Michael H. 
Published: September 2010

AbstractThe methodology uses commercially available esters (II) and (V), is operationally simple and tolerates a broad spectrum of functionalities.
ChemInform Abstract: Simple and Efficient Synthesis of 2‐Aryl‐2,3‐dihydroquinolin‐4(1H)‐ones Using Silica Chloride as a New Catalyst under Solvent‐Free Conditions.
Authors: Muthukrishnan M. , Mujahid M. , Punitharasu V. , Dnyaneshwar D. A. 
Published: September 2010

AbstractTitle compounds (II) are also obtained from a similar one‐pot reaction between 2‐aminoacetophenone and aromatic aldehydes, but yields are only poor.
ChemInform Abstract: Amberlite IRA 402(OH): An Efficient Mediator for the Exclusive Synthesis of Fused Tricyclic Oxaza Quinolinium Salts.
Authors: Paira Rupankar , Paira Priyankar , Maity Arindam , Mondal Shyamal , Hazra Abhijit , Sahu Krishnendu B. , Naskar Subhendu , Saha Pritam , Banerjee Maitreyee , Mondal Nirup B. 
Published: September 2010

AbstractThe improved protocol for the preparation of the biologically interesting title compounds uses the Amberlite resin instead of phase transfer catalysts.
ChemInform Abstract: Triethylamine Promoted Efficient Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones/thiones Using a Solvent‐Free Biginelli Condensation.
Authors: Debache Abdelmadjid , Ghalem Wassima , Boulcina Raouf , Belfaitah Ali , Rhouati Salah , Carboni Bertrand 
Published: September 2010

AbstractAn efficient and environmentally benign protocol for the synthesis of 3,4‐dihydropyrimidin‐2(1H)‐ones and ‐thiones (IV) is described.
ChemInform Abstract: Synthesis, Reactions, and Antimicrobial Evaluation of Some Polycondensed Thienopyrimidine Derivatives.
Authors: Rashad Aymn E. , Shamroukh Ahmed H. , Abdel‐Megeid Randa E. , El‐Sayed Wael A. 
Published: September 2010

AbstractA variety of novel polycondensed thienopyrimidine derivatives are synthesized starting from 2‐aminoindenothiophene‐3‐carboxylic amide (I).
ChemInform Abstract: Synthesis of 2,3‐Dihydroquinazoline‐4(1H)‐ones.
Authors: Shaterian Hamid Reza , Oveisi Ali Reza , Honarmand Moones 
Published: September 2010

AbstractA practical method for the synthesis of the title compounds via three‐component reaction of isatoic anhydride (I) with aromatic aldehydes and primary amines or ammonium salts under solvent‐free conditions is developed.
ChemInform Abstract: (S)‐3‐(4‐(2‐(5‐Methyl‐2‐phenyloxazol‐4‐yl)ethoxy)phenyl)‐2‐ (piperazin‐1‐yl)‐propanoic Acid Compounds: Synthesis and Biological Evaluation of Dual PPARα/γ Agonists.
Authors: Zhou Xinbo , Chen Wei , Xu Cheng , Fan Shiyong , Xie Yunde , Zhong Wu , Wang Lili , Li Song 
Published: September 2010

AbstractA series of novel piperazinylpropanoic acid derivatives (I) are designed, synthesized and evaluated as dual PPARα/γ agonists.
ChemInform Abstract: Stereoselective Synthesis of Tetrasubstituted Alkenylboronates via 1,1‐Organodiboronates.
Authors: Endo Kohei , Hirokami Munenao , Shibata Takanori 
Published: September 2010

AbstractA facile and stereoselective method to prepare (E)‐tetrasubstituted target compounds as versatile building blocks is presented.
ChemInform Abstract: Synthesis of [1‐(Dimethylamino)alkyl]phosphonates from (1‐Hydroxyalkyl)phosphonates: Transformation of Allylic Hydroxyphosphonates into Allylic Aminophosphonates.
Authors: Kaboudin Babak , Faghihi Mohammad Reza 
Published: September 2010

AbstractThe transformation of substrates (I) succeeds without any catalyst to give the synthetically important novel title compounds (III) in moderate to good yield.
ChemInform Abstract: Synthesis, Spectral Characterization and Antimicrobial Activity of Novel 5‐[(Substituted)methyl] ‐5‐oxo‐1,3,2λ4,5λ 5‐dioxaselenaphosphinan‐2‐ones.
Authors: Reddy S. Subba , Krishna B. Satheesh , Rao V. Koteswara , Raju C. Naga 
Published: September 2010

AbstractTitle compounds (IV) are synthesized starting from tris(bromomethyl)phosphine oxide (I).
ChemInform Abstract: N‐Aryltriazole Ribonucleosides with Potent Antiproliferative Activity Against Drug‐Resistant Pancreatic Cancer.
Authors: Liu Yang , Xia Yi , Fan Yuting , Maggiani Alain , Rocchi Palma , Qu Fanqi , Iovanna Juan L. , Peng Ling 
Published: September 2010

AbstractA variety of novel N‐aryltriazole nucleosides is synthesized via Cu‐mediated C—N cross‐coupling of 3‐aminotriazole ribonucleoside and various aromatic boronic acids.
ChemInform Abstract: Stereoselective Divergent Synthesis of Four Diastereomers of Pachastrissamine (Jaspine B).
Authors: Yoshimitsu Yuji , Inuki Shinsuke , Oishi Shinya , Fujii Nobutaka , Ohno Hiroaki 
Published: September 2010

AbstractPachastrissamine (Ia) and its epimers (Ib) and (II) are prepared to investigate structure—activity relationships.
ChemInform Abstract: Expedient Synthesis, on Large Scale, of Aliphatic Chaetomellic Anhydrides from N‐Allyl‐2,2‐dichlorocarboxyamides.
Authors: Ghelfi Franco , Pattarozzi Mariella , Roncaglia Fabrizio , Giangiordano Valerio , Parsons Andrew F. 
Published: September 2010

AbstractThe title method is suitable for large‐scale production of chaetomellic anhydride (VII).
ChemInform Abstract: Synthesis and Ligand Based 3D‐QSAR of 2,3‐Bis‐benzylidenesuccinaldehyde Derivatives as New Class Potent FPTase Inhibitor, and Prediction of Active Molecules.
Authors: Soung Min‐Gyu , Kim Jong‐Han , Kwon Byoung‐Mog , Sung Nack‐Do 
Published: September 2010

AbstractA series of 29 title compounds of type (I) are prepared by a known procedure and tested as new FPTase inhibitors.
ChemInform Abstract: The Synthesis and Physiological Activity of 2,3,4,5‐Tetrahydro‐1H‐pyrido[4,3‐b]indoles
Authors: Ivachtchenko A. V. , Mitkin O. D. , Kadieva M. G. , Tkachenko S. E. 
Published: September 2010

AbstractReview: 146 refs.
Three‐phase fluidized distillation
Authors: Ravagnani Teresa M.K. , Pereira João A.F.R. 
Published: September 2010

AbstractSeparation efficiency in distillation operations can be improved by modifying the characteristics of the dispersions formed on the trays. The present work reports on the hydrodynamic and mass transfer characteristics of liquid‐solid‐vapour dispersions formed on sieve trays without downcomers of a distillation column operating under total reflux conditions. Murphree efficiency and the operating limits of distillation using the ethanol‐n‐butanol system are analyzed for a large range of vapour velocities and liquid mixture compositions, utilising wettable PVC particles and non‐wettable silicone, PE, and Teflonr̀ particles. It was verified that wettable particles show a drastic reduction in the upper operating limit of vapour velocity, but this does not occur for non‐wettable particles. Tray efficiency can be increased when non‐wettable particles are used, mainly for high vapour velocity operations.
Solubility of sulphur dioxide in mixed polyethylene glycol dimethyl ethers
Authors: Schmidt Kurt A.G. , Mather Alan E. 
Published: September 2010

AbstractThe solubility of sulphur dioxide in mixed polyethylene glycol dimethyl ethers was determined at 25°C, 40°C, 70°C and 100°C. The results were best correlated with the NRTL activity coefficient model. Henry's law constants were obtained from the data and the excess enthalpy of the liquid mixture over the full range of composition was predicted at each temperature. In addition, the enthalpy of mixing and the enthalpy of solution were both determined at infinite dilution. The effect of water on the solubility of sulphur dioxide was also investigated with a 6.04 mass% water solution.
Modelling the continuous drying of a thin sheet of fibres on a cylinder heated by electric induction
Authors: Pérez Sergio , Thérien Normand , Broadbent Arthur Douglass 
Published: September 2010

AbstractThe derived model predicts the evolution of the humidity and temperature of a thin web of fibrous material during drying on the surface of a metal cylinder heated by electric induction. The model explicitly considered heat conduction, convection and radiation, and thermal induction as well as energy transfer caused by the evaporation of the water. It also predicted the process responses to perturbations in the manipulated variables and in the initial humidity of the web entering a small‐scale induction dryer. The manipulated variables included the rotational speed of the cylinder, the electric power fed to the inductors, and the area of the web in contact with the cylinder. The simulations carried out showed a high degree of correspondence between the model predictions and the experimental data.
Uniform flux heat transfer in concentric laminar flow of two immiscible liquids
Authors: Stockman Gordon E. , Epstein Norman 
Published: September 2010

AbstractThe energy equation was solved exactly for fully developed steady laminar flow in a circular pipe of two immncible Newton liquids with a concentric cylindrical interface between them, assuming invariant physical properties of the liquids, uniform heat flux at the wall and fully developed temperature profiles. It is shown that, even if the viscosity of the annular liquid is orders of magnitude smaller than that of the core liquid, the improvement in heat transfer to the core liquid by infection of the annular liquid cannot exceed a factor of 1 8
The life and death of gc: The changeover to si and the declining use of gc in chemical engineering textbooks
Authors: Ruiz‐Beviá Francisco 
Published: September 2010

AbstractThirty years ago, an editorial on metrology in the March 1971 issue of AlChE Journal noted the following: “Recognizing the inevitable, the AlChE Journal will require that all papers submitted after July 1, 1971 conform in notation to the SI System (Système International d'Unités)”. This decision was the starting point for the gradual introduction of the use of the SI System in chemical engineering textbooks, at a substitute for the preceding British System. As a consequence, the use of the gc conversion factor has been also diminishing, gradually but at a slower pace In this paper, the changeover to SI and the declining use of gc in chemical engineering textbooks is analyzed. Firstly, some representative books published before 1971 are studied. Secondly, a special analysis is devoted to transport phenomena books. Finally, a few but significant books published since 1971, have been selected in order to carry out the analysis of the changeover to SI System and the evolution of the use of gc
Synthesis and Photophysics of Novel Soluble Polymeric Zn Metal Complex Based on Bis(8‐hydroxyquinoline) Groups with Benzene Unit
Authors: Huo Yanping , Zhu Shizheng 
Published: September 2010

AbstractA novel ligand: 2,2′‐(1,3‐phenylenedivinylene)bis‐8‐hydroxyquinoline (m‐B8QPH) (4) and the corresponding polymeric metal complex Zn(m‐B8QPH) (5) were designed and synthesized in a convenient way. The luminescence properties of the compounds Zn(m‐B8QPH) (5) and Zn(p‐B8QPH) (9) were investigated by UV‐vis and fluorescence spectra in DMF at room temperature. The experimental results showed that the polymeric complexes 5 and 9 emitted yellow luminescence at 578 and 554 nm in DMF solution. The polymeric complex 5 has demonstrated good solubility in common organic solvents and good thermal stability with high Tg: 261°C. Furthermore, the molecular interactions of 5 with fullerene (C60) and fulleropyrrolidine containing 3,5‐bis(trifluoromethyl)benzene (11) were also investigated, which indicated the metal dye 5 can be used as new fluorescent probe.
Comparison of Sirolimus‐ and Paclitaxel‐Eluting Stents in Patients Undergoing Primary Percutaneous Coronary Intervention for ST‐Elevation Myocardial Infarction: A Meta‐analysis of Randomized Trials
Authors: Li Yong‐le , Wan Zheng , Lu Wen‐li , Wang Jian‐hua 
Published: September 2010

AbstractBackgroundIt has been reported that sirolimus‐eluting stents (SES) and paclitaxel‐eluting stents (PES) have been more effective than bare‐metal stents in reducing restenosis and cardiac events in a broad range of patients with coronary artery disease. However, it is unknown whether there might be differences between these two drug‐eluting stents in terms of efficacy and safety in the setting of acute ST‐segment elevation myocardial infarction (STEMI).HypothesisThe aim of the present study was to compare SES with PES in patients with acute STEMI undergoing primary percutaneous coronary intervention (PCI).MethodsThe published research was scanned by formal searches of electronic databases (PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials) from January 2001 to February 2010. Internet‐based sources of information on the results of clinical trials in cardiology were also searched.ResultsA total of 4 randomized trials were included in the present meta‐analysis, involving 1105 patients (550 in the SES group, 555 in the PES group). SES were significantly more effective in the reduction of angiographic binary (≥50%) restenosis (4.0% vs 9.6%, odds ratio 0.38, 95% confidence interval 0.19 to 0.74, P = 0.004) compared to PES. The differences between SES and PES were not statistically significant with respect to target vessel revascularization (TVR), stent thrombosis, cardiac death, and myocardial infarction.ConclusionsSES are superior to PES in reducing the incidence of restenosis in patients undergoing primary PCI for STEMI, with nonsignificant differences in terms of TVR, cardiac death, myocardial infarction, and stent thrombosis. Copyright © 2010 Wiley Periodicals, Inc.The authors have no funding, financial relationships, or conflicts of interest to disclose.
Thrombo‐Cardiology
Authors: Richard Conti C. 
Published: September 2010

Abstractmagnified image As a medical student I, along with my classmates, learned the coagulation cascade. Later, in 1968 when I passed my internal medicine boards and was on my way to becoming a cardiologist, I thought that was the last I had to remember that complicated series of events and the drugs used to alter coagulation. Little did I know at that time how important coagulation and anti‐coagulation would become for cardiovascular patients. Copyright © 2010 Wiley Periodicals, Inc.
Cholinergic inputs to laryngeal motoneurons functionally identified in vivo in rat: A combined electrophysiological and microscopic study
Authors: Bautista Tara G. , Sun Qi‐Jian , Zhao Wen‐Jing , Pilowsky Paul M. 
Published: September 2010

AbstractThe intrinsic laryngeal muscles are differentially modulated during respiration as well as other states and behaviors such as hypocapnia and sleep. Previous anatomical and pharmacological studies indicate a role for acetylcholine at the level of the nucleus ambiguus in the modulation of laryngeal motoneuron (LMN) activity. The present study investigated the anatomical nature of cholinergic input to inspiratory‐ (ILM) and expiratory‐modulated (ELM) laryngeal motoneurons in the loose formation of the nucleus ambiguus. Using combined in vivo intracellular recording, dye filling, and immunohistochemistry, we demonstrate that LMNs identified in Sprague–Dawley rat receive several close appositions from vesicular acetylcholine transporter‐immunoreactive (VAChT‐ir) boutons. ELMs receive a significantly greater number of close appositions (mean ± standard deviation [SD]: 47 ± 11; n = 5) than ILMs (32 ± 9; n = 8; t‐test P < 0.05). For both LMN types, more close appositions were observed on the cell soma and proximal dendrites compared to distal dendrites (two‐way analysis of variance [ANOVA], P < 0.0001). Using fluorescence confocal microscopy, almost 90% of VAChT‐ir close appositions (n = 45 boutons on n = 4 ELMs) were colocalized with the synaptic marker synaptophysin. These results support a strong influence of cholinergic input on LMNs and may have implications in the differential modulation of laryngeal muscle activity. J. Comp. Neurol. 518:4903–4916, 2010. © 2010 Wiley‐Liss, Inc.
Enhancing P2P live streaming performance by balancing description distribution and available forwarding bandwidth in P2P streaming network
Authors: Lin Chow‐Sing 
Published: September 2010

AbstractIn a peer‐to‐peer (P2P) network, peers not only receive services from the network, but also contribute their own resources to the network. The abundant resources brought by P2P networks have stimulated the wide deployment of resource‐consuming multimedia streaming services over a P2P architecture. Allowing for the heterogeneity of peers in their upload and download bandwidth, most researches adopt the Multiple Description Coding (MDC) technique to enable differentiated streaming services. However, due to the lack of a global view of description availability, they tend to cause the skewed distribution of descriptions and lead to the under‐utilization of aggregated resources on P2P networks. In the paper, we propose a novel approach to balance the distribution of descriptions and available upload bandwidth in the P2P live streaming network. Based on the description distribution and available upload bandwidth, the proposed balancing scheme determines what descriptions a new peer should receive and their source peers such that better system scalability can be achieved. The simulation experiments indicate that our proposed balancing scheme can effectively reduce the server bandwidth consumption and rejection rate. Furthermore, abandoned peers can recover their lost descriptions mostly from the existing peers in the network instead of the server. Copyright © 2010 John Wiley & Sons, Ltd.