bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Nature, Content and Realisation of the Right to a Clean, Healthy and Sustainable Environment
Authors: Preston Brian J 
Published: May 2024

Abstract
The right to a clean, healthy and sustainable environment is being increasingly adopted internationally and nationally. Nevertheless, there remains ambiguity regarding what the right and the correlative duty to protect the right entail. This article examines the nature, content and realisation of the right. The nature of the right is suggested to be a cluster of rights, including civil and political rights, economic, social and cultural rights and other rights. The content of the right has at least three components: substantive, procedural and intertemporal. Realisation of the right depends on the correlative duty to respect, protect and fulfil the right. The content of the duty includes specific obligations to achieve the inviolable element of the right, the minimum core obligations and the progressive realisation of that right using maximum available resources. In this way, the article suggests a conceptual framework that can guide states in better realising the right.
Acoustic logging array signal denoising using U-net and a case study in a TangGu oil field
Authors: Fu Xin , Gou Yang , Wei Fuqiang 
Published: May 2024

AbstractThis study developed a noise-reduction method for acoustic logging array signals using a deep neural network algorithm in the time-frequency domain. Initially, we derived analytical solutions for the received waveforms when the acoustic logging tool was positioned either at the centre or eccentrically within the borehole. To simulate the received waveforms across various formations, we developed a real-axis integration algorithm. Subsequently, we devised a noise-reduction algorithm workflow based on a convolutional neural network and configured the structure and parameters of the U-net using TensorFlow. To address the scarcity of open datasets, we established both signal and noise datasets. The signal dataset was generated using theoretical simulation encompassing various model parameters, while the noise dataset was collected during tool testing and downhole operations. The trained model demonstrated substantial noise-reduction capabilities during validation. To validate the effectiveness of the algorithm, we applied noise reduction to actual data collected during downhole operations in a TangGu oil field, yielding impressive results across different types of noisy data. Therefore, the U-net-based time-domain noise-reduction algorithm proposed in this paper holds the potential to significantly improve the quality of acoustic logging array signals.
Aggressive interactions among white-tailed deer (Artiodactyla: Cervidae) at 4-poster devices for host-targeted tick control
Authors: Bai Ningzhu , Pesapane Risa , Machtinger Erika T , Li Andrew Y 
Published: May 2024

Abstract
White-tailed deer, Odocoileus virginianus Zimmermann (Artiodactyla: Cervidae), are the primary wildlife host for adult stages of blacklegged ticks (Acari: Ixodidae: Ixodes scapularis Say) and an important host for lone star ticks (Acari: Ixodidae: Amblyomma americanum Linnaeus), both of which are vectors of numerous tick-borne pathogens. The 4-poster passive deer treatment device is a topical, host-targeted method to control free-living tick populations and has been proven to successfully reduce tick abundance in several states. Aggressive behavior of white-tailed deer at concentrated feeding stations is hypothesized to interfere with the effective use of 4-poster devices and deer contact with acaricide applicators. We analyzed images collected by camera traps at 4-poster feeding stations deployed at 3 sites in Maryland and found a negative relationship between some aggressive interactions and contact with applicators. Our results emphasize the need for further investigation into whether deer social dynamics can impact 4-poster efficacy for tick control. This study serves as a reminder that intraspecific interactions are important to consider when using host-targeted acaricide approaches.
Multi-scalar and diasporic integration: Kurdish populations in Europe between state, diaspora and geopolitics
Authors: Adamson Fiona B , Dag Veysi , Craven Catherine R 
Published: May 2024

Abstract
This article challenges both methodological nationalist and decolonial approaches to ‘integration’ by drawing attention to how transnational factors—including trans-state diaspora networks and geopolitical relations between European states and Kurdish ‘homelands’—have direct impacts on the integration trajectories of newly arrived Kurdish displaced populations in Europe. Based on over 200 interviews with Kurdish immigrants, including refugees and asylum seekers across seventeen sites in rural and urban regions in six European countries, our research suggests the need to move beyond local and national-level understandings of integration to one which is also transnational, diasporic, and multi-scalar, taking account of the enduring effects of homeland politics on integration determinants. Such a model of integration does not throw out the concept, but recognizes both the protective and empowering role that local and national policies can play in enabling refugee and diaspora populations to function autonomously in a broader transnational and global context.
The black hole masses of high-redshift QSOs
Authors: King Andrew 
Published: May 2024

ABSTRACT
Observations of high-redshift quasars frequently promote suggestions of large black hole masses, whose presence so early in cosmic time is not easily explicable. I consider the parallel with ultraluminous X-ray sources (ULXs) – now known to be stellar-mass black hole (and neutron star) binaries apparently radiating far above their Eddington luminosities LEdd. The true luminosity in ULXs is actually only of order LEdd, for stellar-mass accretors, but has a very anisotropic (‘beamed’) component, plus a near-isotropic component of similar luminosity but much lower specific intensity. Observers viewing ULXs from within the beam but assuming spherical symmetry deduce a luminosity ≫LEdd. These features appear because the accretors are fed mass at highly super-Eddington rates, most of it expelled in high-speed (v &gt; 0.2c) outflows from the accretion disc. I show that in similarly beamed AGN, emission-line properties would be essentially the same as in unbeamed sources, but standard virial mass indicators unusable because velocity widths are dominated by the outflows, not bound motions about the black holes. In an ensemble of this kind the apparently most luminous systems are always the most distant, but have the lowest black hole masses. Interpreting observations of this ensemble without knowing that they are beamed leads instead to very high black hole mass estimates. The analogy with ULXs therefore suggests that high-redshift quasars might actually have central black hole masses which could have grown from stellar values within the lookback time. I consider how one might test these ideas observationally.
EPOCHS Paper V. The dependence of galaxy formation on galaxy structure at z &lt; 7 from JWST observations
Authors: Conselice Christopher J , Basham Justin T F , Bettaney Daniel O , Ferreira Leonardo , Adams Nathan , Harvey Thomas , Ormerod Katherine , Caruana Joseph , Bluck Asa F L , Li Qiong , Roper William J , Trussler James , Irodotou Dimitrios , Austin Duncan 
Published: May 2024

ABSTRACT
We measure the broad impact of galaxy structure on galaxy formation by examining the ongoing star formation and integrated star formation history as revealed through the stellar masses of galaxies at z &lt; 7 based on JWST CEERS data from the Extended Groth Strip (EGS). Using the morphological catalog of 3965 visually classified JWST galaxies from Ferreira et al. (2023), we investigate the evolution of stars, and when they form, as a function of morphological type as well as galaxies classified as passive and starburst through spectral energy distributions. Although disc galaxies dominate the structures of galaxies at z &lt; 7, we find that these discs are in general either ‘passive’, or on the main sequence of star formation, and do not contain a large population of starburst galaxies. We also find no significant correlation between morphological type and the star formation rate or colours of galaxies at z &lt; 7. In fact, we find that the morphologically classified ‘spheroids’ tend to be blue and are not found to be predominately passive systems at z &gt; 1.5. We also find that the stellar mass function for disc galaxies does not evolve significantly during this time, whereas other galaxy types, such as the peculiar population, evolve dramatically, declining at lower redshifts. This indicates that massive peculiars are more common at higher redshifts. We further find that up to z ∼ 7, the specific star formation rate (sSFR) does not vary with visual morphology, but strongly depends on stellar mass and internal galaxy mass density. This demonstrates that at early epochs galaxy assembly is a mass-driven, rather than a morphologically driven process. Quenching of star formation is therefore a mass-dominated process throughout the universe’s history, likely due to the presence of supermassive black holes.
MARTIANS (MARs2020, TIANwen and So on) would see more potentially hazardous asteroids than Earthlings
Authors: Zhou Yufan Fane , Li Hailiang , Li Zhiyuan , Zhou Liyong 
Published: May 2024

ABSTRACT
Potentially Hazardous Asteroids (PHAs) are a special subset of Near-Earth Objects (NEOs) that can come close to the Earth and are large enough to cause significant damage in the event of an impact. Observations and researches of Earth-PHAs have been underway for decades. Here, we extend the concept of PHAs to Mars and study the feasibility of detecting Mars-PHAs in the near future. We focus on PHAs that truly undergo close approaches with a planet (dubbed CAPHAs) and aim to compare the actual quantities of Earth-CAPHAs and Mars-CAPHAs by conducting numerical simulations incorporating the Yarkovsky effect, based on observed data of the main asteroid belt. The estimated number of Earth-CAPHAs and Mars-CAPHAs are 4675 and 16910, respectively. The occurrence frequency of Mars-CAPHAs is about 52 per year, which is 2.6 times that of Earth-CAPHAs, indicating significant potential for future Mars-based observations. Furthermore, a few Mars-CAPHAs are predicted to be observable even from Earth around the time of next Mars opposition in 2025.
Molecular phylogenetics of the trochid subfamily Umboniinae (Gastropoda: Trochoidea): working towards a new systematic framework
Authors: Williams Suzanne T , Dyal Patricia , Herbert David G 
Published: May 2024

ABSTRACT
We present here the most taxon-rich phylogeny for the trochid subfamily Umboniinae published to date, with representatives from 14 of the 19 known genera, and as a result show that Umboniinae needs comprehensive taxonomic and systematic revision. We identified one clade corresponding to a new genus with four species collected from deeper water than is typical of most umboniine taxa and one new species likely belonging to a second, undescribed genus (all to be described elsewhere). Only four genera, as currently interpreted were recovered, as monophyletic: Umbonium, Lirularia, Monilea and Rossiteria. Zethalia (monotypic for extant taxa), Pseudominolia, Isanda and Parminolia were all represented by a single species (the latter by Gibbula vanwalleghemi; Poppe, Tagaro & Dekker, 2006). Conotalopia, Ethalia, Ethaliella, Ethminolia, Sericominolia and Vanitrochus were all polyphyletic. We formally recognize the following new combinations: Sericominolia glaphyrella (Melvill & Standen, 1895), Sericominolia vitiliginea (Menke, 1843), Vanitrochus ornatus (Sowerby III, 1903) and Parminolia vanwalleghemi (Poppe, Tagaro & Dekker, 2006), although further molecular studies are desirable to confirm these decisions. The first three generic reassignments make Sericominolia and Vanitrochus monophyletic in our tree. We also suggest that Ethaliella cf. rhodomphala (Souverbie, 1875) should be transferred to one of several clades with species previously assigned to Ethminolia, for which an appropriate genus name has not yet been resolved. This decision makes Ethaliella monophyletic. We also identified several cryptic species complexes, including Rossiteria nucleus (Philippi, 1850), the type species of Rossiteria. The phylogeny presented is a first step towards a more resolved systematic framework for Umboniinae and will allow future studies of key morphological innovations.
Factors contributing to the improvement in Japanese Health Assessment Questionnaire after 3 years of treatment with abatacept in biologic-naïve rheumatoid arthritis patients: Interim results of a long-term, observational, multicentre study in Japan (ORIGAMI)
Authors: Misaki Kenta , Tanaka Eiichi , Inoue Eisuke , Tamura Naoto , Hirano Fuminori , Taniguchi Yoshinori , Sato Hiroshi , Naniwa Taio , Oshikawa Hideto , Yoshitama Tamami , Takakubo Yuya , Suzuki Yoko , Himeno Shinkichi , Tsuritani Katsuki , Matsumoto Shigeru , Yamanaka Hisashi , Harigai Masayoshi 
Published: May 2024

ABSTRACT

Objectives
We investigated the long-term effectiveness, safety, and factors affecting Japanese Health Assessment Questionnaire (J-HAQ) improvement during abatacept treatment in Japanese rheumatoid arthritis (RA) patients.

Methods
The Orencia® Registry in Geographically Assembled Multicenter Investigation (ORIGAMI) study is an ongoing observational study of biologic-naïve RA patients with moderate disease activity treated with subcutaneous abatacept (125 mg, once weekly). Patients treated with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) were extracted from the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) registry as a historical, weighted control group. The primary end point for this interim analysis was the proportion of patients with J-HAQ remission (score ≤0.5) at 3 years.

Results
Among 279 abatacept-treated and 220 csDMARD-treated patients, J-HAQ remission was achieved at 3 years in 40.5% [95% confidence interval (CI) 34.7–46.2%] and 28.9% (95% CI 9.9–47.8%), respectively. Age, RA duration &lt;1 year, baseline J-HAQ score, and Simplified Disease Activity Index remission at 6 months were associated with 3-year J-HAQ remission in the abatacept group. Overall, 24/298 patients (8.1%; safety analysis set) experienced serious adverse drug reactions with an incidence of 5.3 per 100 person-years.

Conclusions
This study confirmed the 3-year effectiveness and safety and revealed potential factors associated with J-HAQ remission in biologic-naïve RA patients treated with abatacept in real-world clinical practice.
The impacts of dietary antioxidants on cardiovascular events in hemodialysis patients: An update on the cellular and molecular mechanisms
Authors: Zununi Vahed Sepideh , Hejazian Seyyedeh Mina , Ardalan Mohammadreza , Anagnostou Fani , Pavon-Djavid Graciela , Barzegari Abolfazl 
Published: May 2024

Abstract
Cardiovascular-related complications (CVCs) are the primary cause of death in patients undergoing hemodialysis (HD), accounting for greater than half of all deaths. Beyond traditional risk factors, chronic inflammation, extreme oxidative stress (OS), and endothelial dysfunction emerge as major contributors to accelerated CVCs in HD patients. Ample evidence shows that HD patients are constantly exposed to excessive OS, due to uremic toxins and pro-oxidant molecules that overwhelm the defense antioxidant mechanisms. The present study highlights the efficiency of natural antioxidant supplementation in managing HD-induced inflammation, OS, and consequently CVCs. Moreover, it discusses the underlying molecular mechanisms by which these antioxidants can decrease mitochondrial and endothelial dysfunction and ameliorate CVCs in HD patients. Given the complex nature of OS and its molecular pathways, the utilization of specific antioxidants as a polypharmacotherapy may be necessary for targeting each dysregulated signaling pathway and reducing the burden of CVCs.
Conjugated linoleic acid metabolite impact in colorectal cancer: a potential microbiome-based precision nutrition approach
Authors: González Adriana , Fullaondo Asier , Rodríguez Javier , Tirnauca Cristina , Odriozola Iñaki , Odriozola Adrian 
Published: May 2024

Abstract
Colorectal cancer (CRC) is the second most deadly and the third most diagnosed cancer in both sexes worldwide. CRC pathogenesis is associated with risk factors such as genetics, alcohol, smoking, sedentariness, obesity, unbalanced diets, and gut microbiota dysbiosis. The gut microbiota is the microbial community living in symbiosis in the intestine, in a dynamic balance vital for health. Increasing evidence underscores the influence of specific gut microbiota bacterial species on CRC incidence and pathogenesis. In this regard, conjugated linoleic acid (CLA) metabolites produced by certain gut microbiota have demonstrated an anticarcinogenic effect in CRC, influencing pathways for inflammation, proliferation, and apoptosis. CLA production occurs naturally in the rumen, and human bioavailability is through the consumption of food derived from ruminants. In recent years, biotechnological attempts to increase CLA bioavailability in humans have been unfruitful. Therefore, the conversion of essential dietary linoleic acid to CLA metabolite by specific intestinal bacteria has become a promising process. This article reviews the evidence regarding CLA and CLA-producing bacteria as therapeutic agents against CRC and investigates the best strategy for increasing the yield and bioavailability of CLA. Given the potential and limitations of the present strategies, a new microbiome-based precision nutrition approach based on endogenous CLA production by human gut bacteria is proposed. A literature search in the PubMed and PubMed Central databases identified 794 papers on human gut bacteria associated with CLA production. Of these, 51 studies exploring association consistency were selected. After excluding 19 papers, due to health concerns or discrepancies between studies, 32 papers were selected for analysis, encompassing data for 38 CLA-producing bacteria, such as Bifidobacterium and Lactobacillus species. The information was analyzed by a bioinformatics food recommendation system patented by our research group, Phymofood (EP22382095). This paper presents a new microbiome-based precision nutrition approach targeting CLA-producing gut bacterial species to maximize the anticarcinogenic effect of CLA in CRC.
Acute Coxiella burnetii Infection: A 10-Year Clinical Experience at a Tertiary Care Center in the United States
Authors: El Zein Said , Challener Doug W , Ranganath Nischal , Khodadadi Ryan B , Theel Elitza S , Abu Saleh Omar M 
Published: May 2024

Abstract

Background
Identifying and treating patients with acute Q fever who are at an increased risk of progressing to persistent disease is crucial for preventing future complications. In this study, we share our decade-long clinical experience with acute Q fever, highlighting the challenges that clinicians encounter from making an initial diagnosis and performing risk stratification to determining the appropriate prophylaxis regimen and duration.

Methods
We retrieved records of adult Mayo Clinic patients (≥18 years) with positive Coxiella burnetii serology results between 1 January 2012 and 31 March 2022. Patients with Q fever anti–phase II immunoglobulin G ≥1:256 by indirect immunofluorescence were further analyzed.

Results
Thirty-one patients were included. Their median age was 58 years (IQR, 50–64), and the majority were men (84%). Acute hepatitis (29%), flu-like illness (25.8%), and pneumonia (16%) were the most common presentations. Thirteen patients (42%) received antibiotic prophylaxis to prevent disease progression, with significant variation in the indications and duration across physicians. The combination of doxycycline and hydroxychloroquine was the preferred regimen. Prophylaxis was administered for a median 333 days (IQR, 168–414). Four patients (13%) progressed to Q fever native valve infective endocarditis, with elevated anticardiolipin immunoglobulin G levels being the sole risk factor in 2 cases. The small sample size precluded drawing conclusions on the impact of prophylaxis in preventing disease progression.

Conclusions
Management of acute Q fever is complicated by the lack of comprehensive clinical guidelines leading to varied clinical practices. There is a critical need for randomized trials to establish robust evidence-based protocols for management.
The Complex Latent Structure of Attenuated Psychotic Symptoms: Hierarchical and Bifactor Models of SIPS Symptoms Replicated in Two Large Samples at Clinical High Risk for Psychosis
Authors: Cowan Henry R , Williams Trevor F , Mittal Vijay A , Addington Jean , Bearden Carrie E , Cadenhead Kristin S , Cannon Tyrone D , Cornblatt Barbara A , Keshevan Matcheri , Perkins Diana O , Mathalon Daniel H , Stone William , Woods Scott W , Walker Elaine F 
Published: May 2024

Abstract

Background and Hypothesis
The Structured Interview for Psychosis-Risk Syndromes (SIPS) and other assessments of psychosis risk define clinical high risk for psychosis (CHR) by the presence of attenuated psychotic symptoms. Despite extensive research on attenuated psychotic symptoms, substantial questions remain about their internal psychometric structure and relationships to comorbid non-psychotic symptoms.

Study Design
Hierarchical and bifactor models were developed for the SIPS in a large CHR sample (NAPLS-3, N = 787) and confirmed through preregistered replication in an independent sample (NAPLS-2, N = 1043). Criterion validity was tested through relationships with CHR status, comorbid symptoms/diagnoses, functional impairment, demographics, neurocognition, and conversion to psychotic disorders.

Study Results
Most variance in SIPS items (75%–77%) was attributable to a general factor. Hierarchical and bifactor models included a general factor and five specific/lower-order factors (positive symptoms, eccentricity, avolition, lack of emotion, and deteriorated thought process). CHR participants were elevated on the general factor and the positive symptoms factor. The general factor was associated with depressive symptoms; functional impairment; and mood, anxiety, and schizotypal personality diagnoses. The general factor was the best predictor of psychotic disorders (d ≥ 0.50). Positive symptoms and eccentricity had specific effects on conversion outcomes. The deteriorated thought process was least meaningful/replicable.

Conclusions
Attenuated psychotic symptoms, measured by the SIPS, have a complex hierarchical structure with a strong general factor. The general factor relates to internalizing symptoms and functional impairment, emphasizing the roles of general psychopathological distress/impairment in psychosis risk. Shared symptom variance complicates the interpretation of raw symptom scores. Broad transdiagnostic assessment is warranted to model psychosis risk accurately.