bluuebunny/crossref_metadata_2025_split huggingface dataset:
Description and crystal structure of nyholmite, a new mineral related to hureaulite, from Broken Hill, New South Wales, Australia
Authors: Elliott P. , Turner P. , Jensen P. , Kolitsch U. , Pring A. 
Published: December 2009

AbstractNyholmite, Cd3Zn2(AsO3OH)2(AsO4)2·4H2O, from the Block 14 Opencut, Broken Hill, New South Wales, Australia, is a new Cd-Zn arsenate species, isostructural with the minerals of the hureaulite group. The mineral occurs in a quartz-garnet-arsenopyrite matrix as white globules, tufted aggregates of fibrous crystals and radiating hemispheres of thin, colourless, bladed crystals. Associated minerals are goldquarryite, lavendulan-sampleite, scorodite-strengite and gypsum. Individual crystals are up to 0.2 mm in length and 0.05 mm across. The mineral is transparent to translucent with a vitreous lustre. It is brittle with an uneven fracture and a white streak. The Mohs hardness is 3–3.5 and the calculated density is 4.23 g cm–3 for the empirical formula. Electron microprobe analyses yielded CdO 34.58, ZnO 9.72, MnO 3.59, CuO 3.39, Al2O3 0.20, CaO 0.16, PbO 0.37, As2O5 34.55, P2O5 6.29 totalling 92.85 wt.%. The empirical formula, based on 20 oxygen atoms, is Ca0.03Pb0.02 Cd2.80Al0.04Zn1.24-Cu0.44Mn0.53[(AsO4)3.13(PO4)0.92]Σ4.05H1.91·3.79H2O. Nyholmite is monoclinic, C2/c, a = 18.062(4) Å, b = 9.341(2) Å, c = 9.844(2) Å, β = 96.17(3)°, V = 1651.2(6) Å3 (single-crystal data, at 123 K). The six strongest lines in the X-ray powder diffraction pattern are [d(Å),I,(hkl)]: 8.985,30,(200); 8.283,85,(110); 6.169,25,(111); 4.878,25,(002); 3.234,100,(2, 420); 3.079,65,(222, 511); 2.976’45’(113). The crystal structure was solved by Patterson methods and refined using 2045 observed reflections to R1(F) = 3.73%. The structure is characterized by a kinked, five-membered chain of edge-sharing Mφ6 (φ = unspecified anion) octahedra, or pentamer, that extends in the a direction. The pentamers link by sharing corners to form a sheet in the (001) plane. Pentamers are also linked, via corner-sharing, by (As,P)O4 groups forming thick slabs in the (001) plane. The slabs link in the c direction by cornersharing between octahedra and tetrahedra to form a dense heteropolyhedral framework. Moderate to weak hydrogen-bonding provides additional linkage between the slabs.
The magnetite ore districts of the southern Aosta Valley (Western Alps, Italy): a mineralogical study of metasomatized chromite ore
Authors: Rossetti P. , Gatta G. D. , Diella V. , Carbonin S. , Della Giusta A. , Ferrario A. 
Published: December 2009

AbstractIn the southern Aosta Valley (Italian Western Alps), several massive magnetite bodies occur within serpentinized ultramafic rocks belonging to the Mesozoic meta-ophiolite nappe. The ultramafic rocks consist of lherzolite with minor dunite bodies and show a high pressure metamorphic overprint. The results of a multi-methodological study, based on optical microscopy, electron microprobe analysis and single-crystal X-ray diffraction, are reported here in order to give new insights into (1) the mineralogy and crystal chemistry of spinels and silicates and (2) the genesis of the massive magnetite bodies. Chromium-rich relict cores inside the magnetite grains suggest a derivation from primary chromite concentrations. The major-element behaviour shows the presence of two chromite types: a Cr2O3-rich (Al2O3-poor) type and a Cr2O3-poor (Al2O3-rich) type. Magnetite ore deposits probably represent the product of transformation from a chromite proto-ore which formed in ultramafic rocks pertaining to an ophiolite suite. The transformation of chromite to magnetite occurred during multiple stages: the pre- metamorphic setting of the ultramafics and the petrographic evidence suggest that metasomatism started before the onset of the alpine metamorphism and was active during the early alpine, eclogite- facies metamorphic overprint related to a subduction process under high fluid activity.
From structure topology to chemical composition. X. Titanium silicates: the crystal structure and crystal chemistry of nechelyustovite, a group III Ti-disilicate mineral
Authors: Cámaraite F. , Sokolova E. 
Published: December 2009

AbstractThe crystal structure of nechelyustovite, ideally Na4Ba2Mn1.5☐2.5Ti5Nb(Si2O7)4O4(OH)3F(H2O)6, a 5.447(1) Å, b 7.157(1) Å, c 47.259(9) Å, α 95.759(4)°, β 92.136(4)°, γ 89.978(4)°, V 1831.7(4) Å3, space group P, Z = 2, Dcalc. 3.041 g cm–3, from Lovozero alkaline massif, Kola Peninsula, Russia, has been solved and refined to R1 = 13.9% on the basis of 1745 unique reflections (Fo > 15σF). Electron microprobe analysis yielded the empirical formula (H20)6.01, Z = 2, calculated on the basis of 42 (O + F) a.p.f.u., H2O and OH are calculated from structure refinement (H2O = 6 p.f.u.; F + OH = 4 p.f.u.). The crystal structure of nechelyustovite is a combination of a TS (titanium silicate) block and an I (intermediate) block. The TS block consists of HOH sheets (H-heteropolyhedral, O-octahedral). The TS block exhibits linkage and stereochemistry typical for Group III (Ti = 3 a.p.f.u.) of Ti-disilicate minerals: two H sheets connect to the O sheet such that two (Si2O7) groups link to the trans edges of a Ti octahedron of the O sheet. There are two distinct TS blocks of the same topology, TS1 and TS2, that differ in the cations of the O sheet, [(Na1.5Mn1☐0.5)Ti] and [(Na2Mn0.5☐0.5)Ti] (4 a.p.f.u.) respectively. The TS1 and TS2 blocks have two different H sheets, H1,2 and H3,4, where (Si2O7) groups link to [5]- and [6]-coordinated (Ti,Nb) polyhedra respectively. There are three peripheral sites, AP(1—3), occupied mainly by Ba (less Sr and K) at 96, 86 and 26% and one peripheral site AP(4) occupied by Na at 50%. There are two I blocks: the I1 block is a layer of Ba atoms; the I2 block consists of H2O groups and AP(3) atoms. TS blocks alternate with I blocks or link through hydrogen bonds (as in epistolite). There is a sequence of four TS blocks and three I blocks per the c cell parameter: TS2 — I1 — TS1 — I2 — TS1 — I1 — TS2.
Compositional variation in the chevkinite group: new data from igneous and metamorphic rocks
Authors: Macdonald R. , Belkin H. E. , Wall F. , Baginski B. 
Published: December 2009

AbstractElectron microprobe analyses are presented of chevkinite-group minerals from Canada, USA, Guatemala, Norway, Scotland, Italy and India. The host rocks are metacarbonates, alkaline and subalkaline granitoids, quartz-bearing pegmatites, carbonatite and an inferred K-rich tuff. The analyses extend slightly the range of compositions in the chevkinite group, e.g. the most MgO-rich phases yet recorded, and we report two further examples where La is the dominant cation in theAsite. Patchily- zoned crystals from Virginia and Guatemala contain both perrierite and chevkinite compositions. The new and published analyses are used to review compositional variation in minerals of the perrierite subgroup, which can form in a wide range of host rock compositions and over a substantial pressure- temperature range. The dominant substitutions in the various cation sites and a generalized substitution scheme are described.
Fluoro-aluminoleakeite, NaNa2(Mg2Al2Li)Si8O22F2, a new mineral of the amphibole group from Norra Kärr, Sweden: description and crystal structure
Authors: Oberti R. , Cámaraite F. , Hawthorne F. C. , Ball N. A. 
Published: December 2009

AbstractFluoro-aluminoleakeite, ideally , is a new mineral of the amphibole group from Norra Kärr, Sweden (IMA-CNMMNC 2009-012). It occurs in a proterozoic alkaline intrusion that mainly comprises a fine-grained schistose agpaitic nepheline-syenite (grennaite). Fluoro- aluminoleakeite occurs as isolated prismatic crystals 0.10–2 mm long in a syenitic matrix. Crystals are light greenish-blue with a greenish-blue streak. It is brittle, has a Mohs hardness of 6 and a splintery fracture; it is non-fluorescent with perfect {110} cleavage, no observable parting, and has a calculated density of 3.14 g cm–3. In plane-polarized light, it is pleochroic, X = pale green, Y = dark green, Z = pale green; X ^ a = 62.9° (in β obtuse), Y || b. Fluoro-aluminoleakeite is biaxial negative, α = 1.632(1), β = 1.638(1), γ = 1.643(1); 2Vobs. = 98.0(4)°, 2Vcalc. = 95.5°.MFluoro-aluminoleakeite is monoclinic, space group C2/m, a = 9.7043(5) Å, b = 17.7341(8) Å, c = 5.2833(3) Å, β = 104.067(4)°, V = 882.0(2) Å3, Z = 2. The eight strongest X-ray diffraction lines in the powder-diffraction pattern are [d in Å, (I), (hkl)]: 2.687, (100), (31, 151); 4.435, (80), (021, 040); 3.377, (80), (131); 2.527, (60), (02); 8.342, (50), (110); 3.096, (40), (310); 2.259, (40), (71, 12) and 2.557, (30), (002, 061). Analysis, by a combination of electron microprobe and crystal-structure refinement, gives SiO2 58.61, Al2O3 7.06, TiO2 0.32, FeO 3.27, Fe2O3 6.05, MgO 8.61, MnO 0.73, ZnO 0.43, CaO 0.05, Na2O 9.90, K2O 2.43, Li2O 1.62, F 3.37, H2Ocalc. 0.50, sum 101.08 wt.%. The formula unit, calculated on the basis of 24 (O,OH,F,Cl) p.f.u. with (OH) + F = 2 a.p.f.u., is A(Na0.65 O22W(F1.47OH0.53)Σ=2.00. Crystal-structure analysis shows CLi to be completely ordered at the M(3) site, and provided reliable site populations. Fluoro-aluminoleakeite is related to the end-member leakeite, , by the substitutions CFe3+ → CAl and WF → W(OH).
The crystal structure of Ga-rich plumbogummite from Tsumeb, Namibia
Authors: Mills S. J. , Kampf A. R. , Raudsepp M. , Christy A. G. 
Published: December 2009

AbstractGa-rich plumbogummite, (Pb0.87,Ca0.13)Σ1.00H(Al1.95,Ga1.05)Σ3.00(PO4)2(OH)6, from Tsumeb, Namibia, has rhombohedral symmetry, space group Rm, with the cell parameters a = 7.0752(19) Å, c = 16.818(4) Å and V = 729.1(3) Å3. The crystal structure has been refined to R1 = 2.05%. Ga-rich plumbogummite has an alunite-type structure comprised of a rhombohedral stacking of (001) composite layers of corner-shared (Al,Ga)O6 octahedra and PO4 tetrahedra, with Pb atoms occupying icosahedrally coordinated sites between the layers. The Pb and H positions are discussed. Ga-rich plumbogummite is nonpleochroic, uniaxial (+), with indices of refraction, ε = 1.742(3) and ω = 1.722(3), determined in white light. The five strongest powder-diffraction lines [d in Å, (I/I°), (hkl)] are: 2.995, (100), (113); 5.766, (95), (101); 2.236, (43), (107, 122); 3.539, (38), (110); 1.919 (32), (303, 033).
Cámaraite, Ba3NaTi4(Fe2+,Mn)8(Si2O7)4O4(OH,F)7. I. A new Ti-silicate mineral from the Verkhnee Espe Deposit, Akjailyautas Mountains, Kazakhstan
Authors: Sokolova E. , Abdu Y. , Hawthorne F. C. , Stepanov A. V. , Bekenova G. K. , Kotel’nikov P. E. 
Published: December 2009

AbstractCámaraite, ideally Ba3NaTi4(Fe2+,Mn)8(Si2O7)4O4(OH,F)7, is a new mineral from the Verkhnee Espe deposit, Akjailyautas Mountains, Kazakhstan. It occurs as intergrowths with bafertisite and jinshajiangite in separate platy crystals up to 8 mm × 15 mm × 2 mm in size, or as star-shaped aggregates of crystals with different orientations. Individual crystals are orange-red to brownish-red, and are platy on {001}. Cámaraite is translucent and has a pale-yellow streak, a vitreous lustre, and does not fluoresce under cathode or ultraviolet light. Cleavage is {001} perfect, no parting was observed, and Mohs hardness is <5; the mineral is brittle. The calculated density is 4.018 g cm-3. In transmitted light, camaraite is strongly pleochroic, X = light brown, Y = reddish-brown, Z = yellow- brown, with Z < X < Y. Cámaraite is biaxial +ve and 2Vmeas. = 93(1)°. All refractive indices are greater than 1.80. Cámaraite is triclinic, space group C, a = 10.678(4) Å, b = 13.744(8) Å, c = 21.40(2) Å, α = 99.28(8)°, β = 92.38(5)°, γ = 90.00(6)°, V = 3096(3) Å3, Z = 4, a:b:c = 0.7761:1:1.5565. The seven strongest lines in the X-ray powder-diffraction pattern are as follows: [d (Å), (I), (hkl)]: 2.63, (100), (401); 2.79, (90), (3, 41, 26, 225); 1.721, (70), (11, 49, 02); 3.39, (50), (24, 223); 3.18, (50), (5, 24); 2.101, (50), (2, 40); 1.578, (50), (1, 2, 61, 40). Chemical analysis by electron microprobe gave: Nb2O5 1.57, SiO2 25.25, TiO2 15.69, ZrO2 0.33, Al2O3 0.13, Fe2O3 2.77, FeO 16.54, MnO 9.46, ZnO 0.12, MgO 0.21, CaO 0.56, BaO 21.11, Na2O 1.41, K2O 0.84, H2O 1.84, F 3.11, less O:F 1.31, total 99.63 wt.%, where the valence state of Fe was determined by Mössbauer spectroscopy [Fe3+/(Fe2+ + Fe3+) = 0.13(8)] and the H2O content was derived by crystal-structure determination. The resulting empirical formula on the basis of 39 anions is Ca0.05)Σ7.78Si7.97O35.89H3.88F3.11. Cámaraite is a Group-II TS-block mineral in the structure hierarchy of Sokolova (2006). The mineral is named camaraite after Fernando Cámaraite (born 1967) of Melilla, Spain, in recognition of his contribution to the fields of mineralogy and crystallography. The new mineral and mineral name have been approved by the Commission on New Minerals, Nomenclature and Classification, International Mineralogical Association (IMA 2009-11).
Cámaraite, Ba3NaTi4(Fe2+,Mn)8(Si2O7)4O4(OH,F)7. II. The crystal structure and crystal chemistry of a new group-II Ti-disilicate mineral
Authors: Cámara F. , Sokolova E. , Nieto F. 
Published: December 2009

AbstractCámaraite — ideally Ba3NaTi4Fe82+(Si2O7)4O4(OH)4F3 — is triclinic, space group C, a = 10.6965(7) Å, b = 13.7861(9) Å, c = 21.478(2) Å, α = 99.345(1)°, β = 92.315(2)°, γ = 89.993(2)°, V = 3122.6(4) Å3, Z = 4, Dcalc. = 4.018 g cm–3, from the Verkhnee Espe alkaline deposit, Akjailyautas Mountains, Kazakhstan, has been solved and refined to R1 5.87% on the basis of 6682 unique reflections (Fo >4σF). The crystal structure of cámaraite can be described as a combination of a TS block and an intermediate (I) block. The TS (titanium silicate) block consists of HOH sheets (H-heteropolyhedral, O-octahedral), and is characterized by a minimal cell based on translation vectors t1 and t2, with t1 ~5.5 and t2 ~7 Å and t1 ^ t2 close to 90°. We describe the crystal structure of cámaraite using a double minimal cell, with 2t1 and 2t2 translations. In the O sheet, there are eight [6]-coordinated MO sites occupied mainly by Fe2+ and Mn, with minor Fe3+, Mg, Zr, Ca and Zn with <MO–ϕ> = 2.185 Å. Eight MO sites give, ideally Fe82+ p.f.u. In the H sheet, there are four [6]-coordinated MH sites occupied almost solely by Ti (Ti = 4 a.p.f.u.), with <MH–ϕ= = 1.963 Å, and eight [4]-coordinated Si sites occupied solely by Si, with <Si—0> = 1.621 Å. The topology of the TS block is as in Group II of the Ti-disilicates (Ti = 2 a.p.f.u. per minimal cell) in the structure hierarchy of Sokolova (2006). There are six peripheral (P) sites, four [8–12]-coordinated Ba-dominant AP sites, giving ideally 3 Ba p.f.u., and two [10]-coordinated Na-dominant BP sites, giving ideally 1 Na p.f.u. There are two I blocks: the I1 block is a layer of Ba atoms (two AP sites); the I2 block is a layer of Ba (two AP sites) and Na atoms (two BP sites). Along c, there are two types of linkage of TS blocks: (1) TS blocks link via AP cations which constitute the I1 block, and (2) TS blocks link via common vertices of MH octahedra (as in astrophyllite-group minerals) and AP and BP cations which constitute the I2 block. Cámaraite is the only mineral of Group II with two types of linkage of TS blocks and two types of I blocks in its structure. The relation of cámaraite to the Group-II minerals is discussed.
Daliranite, PbHgAs2S6, a new sulphosalt from the Zarshouran Au-As deposit, Takab region, Iran
Authors: Paar W. H. , Pring A. , Moëlo Y. , Stanley C. J. , Putz H. , Topa D. , Roberts A. C. , Braithwaite R. S. W. 
Published: December 2009

AbstractDaliranite, ideally PbHgAs2S6, a new sulphosalt from the Zarshouran Au-As deposit, Takab region, Iran, occurs as a rare sulphosalt species at the Carlin-type Zarshouran Au-As deposit North of the town of Takab in the Province of West Azarbaijan, Iran. The new species is associated with orpiment, rarely with galkhaite, hutchinsonite and cinnabar. The strongly silicified matrix of the specimens has veinlets of sphalerite, with rare inclusions of galena and various (Cu)-Pb-As(Sb) sulphosalts. Daliranite occurs as matted nests of acicular and flexible fibres up to 200 μm in length and a width less than a few μm. The colour is orange-red with a pale orange-red streak and the lustre is adamantine. The mineral is transparent and does not fluoresce. The Mohs hardness is <2. Electron microprobe analyses give the empirical formula Pb0.95Tl0.01Hg1.04As2.10S5.91, ideally PbHgAs2S6, a new sulphosalt from the Zarshouran Au-As deposit, Takab region, Iran; the calculated density is 5.93 g cm–3. Unit-cell parameters were determined by an electron-diffraction study and refined from X-ray powder data. Daliranite is monoclinic primitive with a = 19.113(5) Å, b = 4.233(2) Å, c = 22.958(8) Å, β = 114.78(5)°, V = 1686.4 Å3 and Z = 8, a:b:c = 4.515:1:5.424, space group P2, Pm or P2/m. The strongest X-ray powder-diffraction lines [d in Å, (I), (hkl)] are: 8.676, (80), (200); 4.654, (50), (401); 3.870, (40), (211); 3.394, (50), (113); 3.148, (40b), (602); 2.892, (50), (600); 2.724, (100), (703); 2.185, (50), (319). The formula shows a sulphur excess which may correspond to S—S bonding (persulphide). The new sulphosalt is a late phase in the crystallization sequence, and was formed after orpiment, contemporaneously with quartz II, at a temperature between 157 and 193°C. The name honours Dr Farahnaz Daliran (University of Karlsruhe, Germany) in recognition of her outstanding contributions to research on ore deposits, especially Au, Zn and Fe, in Iran.
Psychological correlates of self-reported functional limitation in patients with ankylosing spondylitis
Authors: Brionez Tamar F , Assassi Shervin , Reveille John D , Learch Thomas J , Diekman Laura , Ward Michael M , Davis John C , Weisman Michael H , Nicassio Perry 
Published: December 2009

Abstract
Introduction
Functional status is an integral component of health-related quality of life in patients with ankylosing spondylitis (AS). The purpose of this study was to investigate the role of psychological variables in self-reported functional limitation in patients with AS, while controlling for demographic and medical variables.

Methods
294 AS patients meeting modified New York Criteria completed psychological measures evaluating depression, resilience, active and passive coping, internality and helplessness at the baseline visit. Demographic, clinical, and radiologic data were also collected. Univariate and multivariate analyses were completed to determine the strength of correlation of psychological variables with functional limitation, as measured by the Bath AS Functional Index (BASFI).

Results
In the multivariate regression analysis, the psychological variables contributed significantly to the variance in BASFI scores, adding an additional 24% to the overall R-square beyond that accounted by demographic and medical variables (R-square 32%), resulting in a final R-square of 56%. Specifically, arthritis helplessness, depression and passive coping beside age, ESR and the Bath AS Radiograph Index accounted for a significant portion of the variance in BASFI scores in the final model.

Conclusions
Arthritis helplessness, depression, and passive coping accounted for significant variability in self-reported functional limitation beyond demographic and clinical variables in patients with AS. Psychological health should be examined and accounted for when assessing functional status in the AS patients.
Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases
Authors: Beck Ilse M. E. , Vanden Berghe Wim , Vermeulen Linda , Yamamoto Keith R. , Haegeman Guy , De Bosscher Karolien 
Published: December 2009

AbstractGlucocorticoids (GCs) are steroidal ligands for the GC receptor (GR), which can function as a ligand-activated transcription factor. These steroidal ligands and derivatives thereof are the first line of treatment in a vast array of inflammatory diseases. However, due to the general surge of side effects associated with long-term use of GCs and the potential problem of GC resistance in some patients, the scientific world continues to search for a better understanding of the GC-mediated antiinflammatory mechanisms.The reversible phosphomodification of various mediators in the inflammatory process plays a key role in modulating and fine-tuning the sensitivity, longevity, and intensity of the inflammatory response. As such, the antiinflammatory GCs can modulate the activity and/or expression of various kinases and phosphatases, thus affecting the signaling efficacy toward the propagation of proinflammatory gene expression and proinflammatory gene mRNA stability. Conversely, phosphorylation of GR can affect GR ligand- and DNA-binding affinity, mobility, and cofactor recruitment, culminating in altered transactivation and transrepression capabilities of GR, and consequently leading to a modified antiinflammatory potential.Recently, new roles for kinases and phosphatases have been described in GR-based antiinflammatory mechanisms. Moreover, kinase inhibitors have become increasingly important as antiinflammatory tools, not only for research but also for therapeutic purposes. In light of these developments, we aim to illuminate the integrated interplay between GR signaling and its correlating kinases and phosphatases in the context of the clinically important combat of inflammation, giving attention to implications on GC-mediated side effects and therapy resistance.
In Search for the “Phenolate” Monoanion of Fluorescein in Solution
Authors: Mchedlov-Petrossyan Nikolay O , Vodolazkaya Natalya A , Salamanova Natalya V , Roshal Alexander D , Filatov Dmitriy Yu 
Published: December 2009

Abstract
Fluorescein is exclusively popular owing to bright fluorescence of its R2− dianion. While the structure of the latter and tautomerism of the H2R form are well established, only the species with COO− and OH groups has been supposed for HR− up to now. Using absorption, emission, and excitation at different pH in non-HBD solvents, DMSO, acetonitrile, and acetone, we reveal that 10–12% of HR− ions nevertheless exist as “phenolate” monoanion with nonionized COOH group.
Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma
Authors: Huang Qiaojia , Ye Jianxin , Huang Qingling , Chen Wannan , Wang Lin , Lin Wansong , Lin Jianyin , Lin Xu 
Published: December 2009

Abstract

Background: In a previous study, we found that heat shock protein 27 (HSP27) was over-expressed in gastric adenocarcinoma (GA) tissue. In this study, our goal was to further verify the expression profile of HSP27 in patients with GA.

Methods: Western blot and immunohistochemistry were employed to determine HSP27 expression in 50 paired tumor and adjacent normal tissue. ELISA was used to quantify serum HSP27 concentrations in the same 50 GA patients and 50 healthy individuals.

Results: Compared to adjacent normal tissues, HSP27 was over-expressed in 25 (50%, p=0.000) and 24 (48%, p=0.000) cases of GA tissue by Western blot and immunohistochemistry, respectively. ELISA revealed significantly higher serum concentrations of HSP27 in patients with GA patients (mean=986 pg/mL) compared to healthy individuals (mean=573 pg/mL) (p=0.003). In addition, infection with Helicobacter pylori (HP) in healthy individuals was associated with increased expression of HSP27 in both gastric mucosa and serum.

Conclusions: These data suggest that HSP27 is over-expressed in GA tissue and serum concentrations of HSP27 are increased in patients with GA. Over-expression of HSP27 may indicate a gastric malignant/infectious process. The detection of serum HSP27 concentrations by ELISA may be useful for screening for GA.
Clin Chem Lab Med 2010;48:263–9.