bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘MAYBE YOU DON'T ACTUALLY EXIST’: CONTAINING SHAME AND SELF‐HARM IN A SCHOOL COUNSELLING SERVICE
Authors: Catty Jocelyn 
Published: January 2012

abstractIn this paper, I argue that the school counsellor occupies a liminal position in the school environment, on the boundary between the private and the public, and that this position intrinsically reflects the paradoxical nature of shame, at once hidden and viewed. I review arguments that locate the development of primitive shame in early containment failure, with shame being defended against by rage against others or the self. I argue that the school counsellor's position commonly oscillates through the three positions of the child–home–school triangle, but that this is felt particularly acutely when the dynamics projected through this triangle are those of shame and shaming. For adolescents, the paradoxical nature of shame also finds a counterpart in self‐harm, a simultaneously hidden and viewed act which I see as a mapping of shame on the body. In exploring the operation of shame in self‐harming students, I also argue that chance encounters between counsellor and student in the external school world render projections about intimacy, intrusion and shame particularly powerful.
Delving into somatic variation in sporadic melanoma
Authors: Walia Vijay , Mu Euphemia W. , Lin Jimmy C. , Samuels Yardena 
Published: January 2012

SummaryMelanoma, the most aggressive form of skin cancer, has increased in incidence more rapidly than any other cancer. The completion of the human genome project and advancements in genomics technologies has allowed us to investigate genetic alterations of melanoma at a scale and depth that is unprecedented. Here, we survey the history of the different approaches taken to understand the genomics of melanoma – from early candidate genes, to gene families, to genome‐wide studies. The new era of whole‐exome and whole‐genome sequencing has paved the way for an in‐depth understanding of melanoma biology, identification of new therapeutic targets, and development of novel personalized therapies for melanoma.
Ameloblastic carcinoma of mandible: Report of intriguing presentation
Authors: Guledgud Mahima V. , Patil Karthikeya , Malleshi Suchetha N. 
Published: January 2012

ABSTRACTAmeloblastic carcinoma, a rare aggressive odontogenic tumor occurs predominantly in the mandibular posterior region. Clinical symptoms are varied with possible metastasis to the regional lymph nodes or lung. Radiographically, it usually manifests as an ill‐defined osteolytic radiolucency. Histologically, it resembles ameloblastoma that is mostly devoid of its familiar microscopic features in combination with prominent cytological atypia and mitotic activity. A rare and atypical presentation of ameloblastic carcinoma of the mandible with unconventional clinical and radiological features is documented in this case report.
Methane source strength and energy flow shape methanotrophic communities in oxygen–methane counter‐gradients
Authors: Krause Sascha , Lüke Claudia , Frenzel Peter 
Published: January 2012

SummaryThe role of microbial diversity for ecosystem functioning has become an important subject in microbial ecology. Recent work indicates that microbial communities and microbial processes can be very sensitive to anthropogenic disturbances. However, to what extent microbial communities may change upon, resist to, or overcome disturbances might differ depending on substrate availability. We used soil from an Italian rice field in gradient microcosms, and analysed the response of methanotrophic communities to an NH4+ pulse as a potential disturbance under two different CH4 source strengths. We found a significant influence of source strength, i.e. the energy flow through the methanotrophic community, while NH4+ had no effect. Our data suggest that historical contingencies, i.e. nitrogen fertilization, led to an ammonium‐tolerant MOB community. Methanotrophs were able to oxidize virtually all CH4 diffusing into the oxic–anoxic boundary layer regardless of NH4+ addition. Total and active methanotrophic communities were assessed by a pmoA‐specific microarray. From the reservoir of dormant methanotrophs, different species became active with Methylobacter and an environmental cluster affiliated with paddy soils being indicative for high CH4 source strength. Thus, a microbial seed bank is an important prerequisite to maintain functioning in a fluctuating environment.
The Use and Role of Pop Culture in Heritage Language Learning: A Study of Advanced Learners of Korean
Authors: Choi Jayoung , Yi Youngjoo 
Published: January 2012

AbstractDespite the important use of pop culture in many instructional settings, its use in the heritage language (HL) classroom remains largely unexplored. Thus, this article reports findings from classroom‐based qualitative research that examined the use and role of pop culture in advanced Korean HL learners’ literacy engagement and identity construction. Data analyses of the learners’ reading presentations and writing projects revealed that they extensively drew upon the heritage media and pop culture for their in‐class literacy practices. Pop culture served as a contact point for their literacy practice, helped reexamine or strengthen their ethnic identity from a global perspective, and provided a window to discuss social issues and explore them. Findings suggest pedagogical implications for using pop culture in HL and foreign language classrooms.
Viewpoint (In)dependence of Action Representations: An MVPA Study
Authors: Oosterhof Nikolaas N. , Tipper Steven P. , Downing Paul E. 
Published: January 2012

AbstractThe discovery of mirror neurons—neurons that code specific actions both when executed and observed—in area F5 of the macaque provides a potential neural mechanism underlying action understanding. To date, neuroimaging evidence for similar coding of specific actions across the visual and motor modalities in human ventral premotor cortex (PMv)—the putative homologue of macaque F5—is limited to the case of actions observed from a first-person perspective. However, it is the third-person perspective that figures centrally in our understanding of the actions and intentions of others. To address this gap in the literature, we scanned participants with fMRI while they viewed two actions from either a first- or third-person perspective during some trials and executed the same actions during other trials. Using multivoxel pattern analysis, we found action-specific cross-modal visual–motor representations in PMv for the first-person but not for the third-person perspective. Additional analyses showed no evidence for spatial or attentional differences across the two perspective conditions. In contrast, more posterior areas in the parietal and occipitotemporal cortex did show cross-modal coding regardless of perspective. These findings point to a stronger role for these latter regions, relative to PMv, in supporting the understanding of others' actions with reference to one's own actions.
On the Influence of Raindrop Collision Outcomes on Equilibrium Drop Size Distributions
Authors: Prat Olivier P. , Barros Ana P. , Testik Firat Y. 
Published: January 2012

Abstract
The objective of this study is to evaluate the impact of a new parameterization of drop–drop collision outcomes based on the relationship between Weber number and drop diameter ratios on the dynamical simulation of raindrop size distributions. Results of the simulations with the new parameterization are compared with those of the classical parameterizations. Comparison with previous results indicates on average an increase of 70% in the drop number concentration and a 15% decrease in rain intensity for the equilibrium drop size distribution (DSD). Furthermore, the drop bounce process is parameterized as a function of drop size based on laboratory experiments for the first time in a microphysical model. Numerical results indicate that drop bounce has a strong influence on the equilibrium DSD, in particular for very small drops (&lt;0.5 mm), leading to an increase of up to 150% in the small drop number concentration (left-hand side of the DSD) when compared to previous modeling results without accounting for bounce effects.
The Effects of Changes in Sea Surface Temperature and CO2 Concentration on the Quasi-Biennial Oscillation
Authors: Kawatani Yoshio , Hamilton Kevin , Noda Akira 
Published: January 2012

Abstract
The effects of sea surface temperature (SST) and CO2 on future changes in the quasi-biennial oscillation (QBO) are investigated using a climate model that simulates the QBO without parameterized nonstationary gravity wave forcing. Idealized model experiments using the future SST with the present CO2 (FS run) and the present SST with the future CO2 (FC run) are conducted, as are experiments using the present SST with the present CO2 (present run) and the future SST with the future CO2 (future run). When compared with the present run, precipitation increases around the equatorial region in the FS run and decreases in the FC run, resulting in increased and decreased wave momentum fluxes, respectively. In the midlatitude lower stratosphere, westward (eastward) wave-forcing anomalies form in the FS (FC) run. In the middle stratosphere off the equator, westward wave-forcing anomalies form in both the FS and FC runs. Corresponding to these wave-forcing anomalies, the residual vertical velocity significantly increases in the lower stratosphere in the FS run but decreases to below 70 hPa in the FC run, whereas residual upward circulation anomalies form in both the FS and FC runs in the middle equatorial stratosphere. Consequently, the amplitude of the QBO becomes smaller in the lower stratosphere, and the period of the QBO becomes longer by about 1–3 months in the FS run. On the other hand, in the FC run, the QBO extends farther downward into the lowermost stratosphere, and the period becomes longer by 1 month.
Color Doppler Ultrasound
Authors: Vakharia Kalpesh T. , Henstrom Douglas , Lindsay Robin , Cunnane Mary Beth , Cheney Mack , Hadlock Tessa 
Published: January 2012

ObjectiveThe gracilis muscle free flap has become a reliable means for smile reanimation for patients with facial paralysis. Because it is a buried flap, it presents a postoperative monitoring challenge. We sought to evaluate our experience with color Doppler ultrasound in the monitoring of gracilis free flap viability in the immediate postoperative setting.Study DesignCase series with planned data collection.SettingTertiary medical center.MethodsPatients with facial paralysis treated with gracilis muscle free flap for smile reanimation performed between March 2009 and November 2010 were evaluated by color Doppler ultrasound and included in the study. Our experience with the use of the color Doppler ultrasound to monitor the gracilis muscle flap is presented.ResultsForty‐six patients were identified. In all cases, color Doppler ultrasound was used postoperatively to assess flow through the vascular pedicle. Outcomes included an early flap survival rate of 100%, with no instances of equivocal or absent flow on either the arterial or venous side. Color Doppler ultrasound provided important objective information regarding muscle perfusion postoperatively in several instances of equivocal postoperative perfusion of the flap.ConclusionColor Doppler ultrasound is a safe, noninvasive method that can be performed serially to evaluate a buried free flap. We have had success in verifying normal arterial and venous flow through the pedicle using this method of monitoring of the gracilis muscle free flap during facial reanimation, and in 3 instances, it eliminated the need for wound exploration to verify appropriate muscle perfusion.
Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity
Authors: Engelhardt Brian G. , Jagasia Shubhada M. , Crowe James E. , Griffith Michelle L. , Savani Bipin N. , Kassim Adetola A. , Lu Pengcheng , Weitkamp Jörn-Hendrik , Moore Daniel J. , Yoder Sandra M. , Rock Michael T. , Jagasia Madan 
Published: January 2012

AbstractChronic inflammation and decreased frequency of regulatory T cells (Tregs) in visceral adipose tissue contribute to the propagation of insulin resistance to diabetes mellitus. We tested the hypothesis that new-onset posttransplantation diabetes mellitus (PTDM) is associated with measurable changes in Treg subsets after allogeneic hematopoietic stem cell transplantation (HSCT). PTDM before day 100 and Treg phenotype at engraftment were determined in 36 HSCT recipients without preceding history of diabetes mellitus. Among patients with new-onset PTDM (N = 24), the frequency of circulating CLA+ (skin-homing) Tregs was decreased (1.53% vs 3.99%; P = .002) and the percentage of α4β7+ (gut-homing) Tregs was increased (17.9% vs 10.7%; P = .048). In multivariate analysis, patients with PTDM continued to demonstrate elevated ratios of α4β7+ Tregs to CLA+ Tregs (odds ratio, 18.1; P = .020). PTDM is associated with altered immune regulation after HSCT and could represent a target to modulate alloreactivity.
Differing clinical characteristics between influenza strains among young healthy adults in the tropics
Authors: Yap Jonathan , Tan Chi Hsien , Cook Alex R , Loh Jin Phang , Tambyah Paul A , Tan Boon Huan , Lee Vernon J 
Published: January 2012

AbstractBackgroundInfluenza infections may result in different clinical presentations. This study aims to determine the clinical differences between circulating influenza strains in a young healthy adult population in the tropics.MethodsA febrile respiratory illness (FRI) (fever ≥ 37.5°C with cough and/or sore throat) surveillance program was started in 4 large military camps in Singapore on May 2009. Personnel with FRI who visited the camp clinics from 11 May 2009 to 25 June 2010 were recruited. Nasal washes and interviewer-administered questionnaires on demographic information and clinical features were obtained from consenting participants. All personnel who tested positive for influenza were included in the study. Overall symptom load was quantified by counting the symptoms or signs, and differences between strains evaluated using linear models.ResultsThere were 434 (52.9%) pandemic H1N1-2009, 58 (7.1%) seasonal H3N2, 269 (32.8%) influenza B, and 10 (1.2%) seasonal H1N1 cases. Few seasonal influenza A (H1N1) infections were detected and were therefore excluded from analyses, together with undetermined influenza subtypes (44 (1.5%)), or more than 1 co-infecting subtype (6 (0.2%)). Pandemic H1N1-2009 cases had significantly fewer symptoms or signs (mean 7.2, 95%CI 6.9-7.4, difference 1.6, 95%CI 1.2-2.0,p< 0.001) than the other two subtypes (mean 8.7, 95%CI 8.5-9.0). There were no statistical differences between H3N2 and influenza B (p= 0.58). Those with nasal congestion, rash, eye symptoms, injected pharynx or fever were more likely to have H3N2; and those with sore throat, fever, injected pharynx or rhinorrhoea were more likely to have influenza B than H1N1-2009.ConclusionsInfluenza cases have different clinical presentations in the young adult population. Pandemic H1N1 influenza cases had fewer and milder clinical symptoms than seasonal influenza. As we only included febrile cases and had no information on the proportion of afebrile infections, further research is needed to confirm whether the relatively milder presentation of pandemic versus seasonal influenza infections applies to all infections or only febrile illnesses.
Robust non-linear differential equation models of gene expression evolution across Drosophila development
Authors: Haye Alexandre , Albert Jaroslav , Rooman Marianne 
Published: January 2012

Abstract

Background
This paper lies in the context of modeling the evolution of gene expression away from stationary states, for example in systems subject to external perturbations or during the development of an organism. We base our analysis on experimental data and proceed in a top-down approach, where we start from data on a system's transcriptome, and deduce rules and models from it without a priori knowledge. We focus here on a publicly available DNA microarray time series, representing the transcriptome of Drosophila across evolution from the embryonic to the adult stage.

Results
In the first step, genes were clustered on the basis of similarity of their expression profiles, measured by a translation-invariant and scale-invariant distance that proved appropriate for detecting transitions between development stages. Average profiles representing each cluster were computed and their time evolution was analyzed using coupled differential equations. A linear and several non-linear model structures involving a transcription and a degradation term were tested. The parameters were identified in three steps: determination of the strongest connections between genes, optimization of the parameters defining these connections, and elimination of the unnecessary parameters using various reduction schemes. Different solutions were compared on the basis of their abilities to reproduce the data, to keep realistic gene expression levels when extrapolated in time, to show the biologically expected robustness with respect to parameter variations, and to contain as few parameters as possible.

Conclusions
We showed that the linear model did very well in reproducing the data with few parameters, but was not sufficiently robust and yielded unrealistic values upon extrapolation in time. In contrast, the non-linear models all reached the latter two objectives, but some were unable to reproduce the data. A family of non-linear models, constructed from the exponential of linear combinations of expression levels, reached all the objectives. It defined networks with a mean number of connections equal to two, when restricted to the embryonic time series, and equal to five for the full time series. These networks were compared with experimental data about gene-transcription factor and protein-protein interactions. The non-uniqueness of the solutions was discussed in the context of plasticity and cluster versus single-gene networks.
Population-based incidence, mortality and quality of life in critically ill patients treated with renal replacement therapy: a nationwide retrospective cohort study in finnish intensive care units
Authors: Vaara Suvi T , Pettilä Ville , Reinikainen Matti , Kaukonen Kirsi-Maija ,   the Finnish Intensive Care Consortium
Published: January 2012

Abstract
Introduction
Acute kidney injury (AKI) increases mortality and morbidity of critically ill patients. Mortality of patients treated with renal replacement therapy (RRT) is high. We aimed to evaluate the nationwide incidence of RRT-treated AKI in Finland, hospital and six-month mortality, and health-related quality of life (HRQoL) of these patients.

Methods
We performed a retrospective cohort study including all general intensive care unit (ICU) admissions in Finland in 2007 through 2008. We identified patients who had received RRT due to AKI (RRT patients) and compared these patients to ICU patients who were not treated with RRT (non-RRT patients). The HRQoL was assessed by the EQ-5D index and visual analogue scale (VAS).

Results
We analysed the final cohort of 24,904 patients, of whom 1,686 received RRT due to AKI. The incidence of RRT-treated AKI was 6.8% (95% confidence interval (CI) 6.5 to 7.1%) among ≥ 15-year-old general ICU patients, which corresponds to a yearly population-based incidence of 19.2 per 100,000 (95% CI 17.9 to 20.5/100,000). According to RIFLE (Risk, Injury, Failure) classification 26.6% (95% CI 26.0 to 27.2%) of patients had AKI (RIFLE R-F). Hospital and six-month mortality of RRT patients were 35.0% and 49.4%. At six-months, RRT patients perceived their health as good as non-RRT patients by VAS.

Conclusions
The population-based incidence of AKI treated with RRT was 19.2 per 100,000 in Finland and 6.8% of all general ICU patients. The hospital and six-month mortality rates were lower than previously reported for ICU-treated RRT patients.
Characterization of Silver Doped Hydroxyapatite Prepared by EDTA Chelate Decomposition Method
Authors: Celik Kubra , Ergun Celaletdin , Kizil Huseyin 
Published: January 2012

ABSTRACTIn this study, Ag doped hydroxyapatite (HA) samples prepared by EDTA chelate decomposition method were characterized with X-Ray Diffraction Spectroscopy (XRD), Scanning Electron Microscopy (SEM) and antimicrobial sensitivity test. Hydroxyapatite (Ca10(PO)6(OH)2) and NaCaPO4 (rhenanite) phases were observed while Ag was present in the form of Ag2O. Results showed that microstructurally controlled HA-based composites with NaCaPO4 interphase can be prepared, which significantly enhances sinterability of hydroxyapatite at 1100° C without formation of any undesired second phases, such as tricalcium phosphate (TCP) known to decrease the stability of HA. The antibacterial sensitivity was tested with E.Coli gram-negative bacteria. The radius of circle enclosing the sample increases with increasing Ag content in the structure as an indication of the region of non-bacterial activity.
Oral and Written Instruction of Oral Hygiene: A Randomized Trial
Authors: Harnacke Daniela , Beldoch Magdalena , Bohn Gertrude‐Heidi , Seghaoui Ouarda , Hegel Nicole , Deinzer Renate 
Published: January 2012

Background: This randomized, evaluator‐masked, controlled study evaluates the effectiveness of oral in contrast to written instruction of oral hygiene.Methods: Eighty‐three students without clinical signs of periodontitis were randomly assigned to either a control group or one of three experimental conditions: 1) written instruction, 2) standardized oral instruction, or 3) individualized oral instruction. Plaque and bleeding indices were assessed to analyze intervention effects on oral health and oral hygiene skills. Measurements took place at baseline and 4 weeks after intervention.Results: Groups differed significantly with respect to gingival bleeding and were tentatively significant with respect to oral hygiene skills. Participants who had received oral individualized instructions showed the best results.Conclusion: A gradient of effectiveness of the instruction methods was observed with most favorable results for the individualized instruction.
Mucositis, Peri‐Implantitis, Implant Success, and Survival of Implants in Patients With Treated Generalized Aggressive Periodontitis: 3‐ to 16‐Year Results of a Prospective Long‐Term Cohort Study
Authors: Swierkot Katrin , Lottholz Peer , Flores‐de‐Jacoby Lavin , Mengel Reiner 
Published: January 2012

Background: The aim of this prospective study is to evaluate the prevalence of mucositis, peri‐implantitis, implant success, and survival in partially edentulous patients treated for generalized aggressive periodontitis (GAgP) and in periodontally healthy individuals.Methods: Thirty‐five patients treated for GAgP and 18 periodontally healthy patients orally rehabilitated with osseointegrated implants participated in the study. They were first examined 2 to 4 weeks before extraction of the non‐retainable teeth (baseline) and 3 weeks after insertion of the final abutments. Additional examinations were performed during a 3‐month recall schedule over a 5‐ to 16‐year period (mean, 8.25 years). At every session, clinical parameters were recorded. At 1, 3, 5, 10, and 15 years after insertion of the superstructure, a microbiological and radiographic examination was performed.Results: The results show implant survival rates of 100% in periodontally healthy individuals versus 96% in GAgP patients. The implant success rate was 33% in GAgP patients and 50% in periodontally healthy individuals. In GAgP patients, mucositis was present in 56% and peri‐implantitis in 26% of the implants. In periodontally healthy individuals, 40% of the implants showed mucositis and 10% peri‐implantitis. GAgP patients had a five times greater risk of implant failure, a three times greater risk of mucositis, and a 14 times greater risk of peri‐implantitis.Conclusion: These results suggest that patients with treated GAgP are more susceptible to mucositis and peri‐implantitis, with lower implant survival and success rates.