bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimierung des Managements der Tragwerksintegrität für Offshore‐Windenergieanlagen
Authors: Thöns Sebastian , Faber Michael Havbro , Rücker Werner 
Published: August 2012

AbstractDieser Artikel enthält aktuelle Forschungsergebnisse im Bereich des überwachungsgestützten Managements der Tragwerksintegrität. Das Management der Tragwerksintegrität hat zum Ziel, die Funktionalität eines Tragwerks während des gesamten Lebenszyklus durch Einhaltung der Zielzuverlässigkeiten sicherzustellen. Ausgehend von Forschungsergebnissen über die Charakteristik von Überwachungsverfahren und ‐daten im Rahmen von Zuverlässigkeitsanalysen, wird ein Ansatz vorgestellt, wie die erwarteten Kosten für das Management der Tragwerksintegrität durch Überwachungsverfahren optimiert werden können. Dazu wird eine Kosten‐Nutzen‐Analyse für den Lebenszyklus einer Gründungstruktur von Offshore‐Windenergieanlagen durchgeführt. Im Rahmen der Bayes'schen Entscheidungstheorie werden durch eine Prä‐posteriori‐Entscheidungsanalyse die optimalen Entscheidungsparameter für den Entwurf eines Überwachungssystems bestimmt. Als Fallstudie wird ein Überwachungssystem für die Gründungsstruktur eines Multibrid‐M5000‐Prototyps konzipiert und die mögliche Reduktion der Risiken und erwarteten Betriebskosten quantifiziert.Optimisation of the structural integrity management for offshore wind turbinesThis paper contains recent research results in the field of monitoring supported structural integrity management. The structural integrity management aims at ensuring the functioning of a structure throughout the life cycle by compliance with the target reliabilities. Building upon research results concerning the characteristics of monitoring techniques and data within the framework of reliability analyses, an approach is introduced for the optimisation of the expected structural integrity management costs by monitoring information. For this aim, a life cycle cost benefit analysis for offshore wind turbine support structures is formulated. The optimal monitoring decision parameters are then assessed utilizing the Bayesian pre‐posterior decision theory. As a case study a monitoring system for a Multibrid M5000 offshore wind turbine prototype support structure is designed and possible reductions of the risks and expected costs are quantified.
Ermüdungsverhalten von Hochleistungsbetonen in Windenergieanlagen
Authors: Lohaus Ludger , Oneschkow Nadja , Elsmeier Kerstin , Hümme Julian 
Published: August 2012

AbstractDie aktuellen Entwicklungen in der Windenergiebranche führen zu Windenergieanlagen mit immer höherer Leistungsfähigkeit. Als Konsequenz aus dieser Entwicklung steigen mit der Leistungsfähigkeit der Anlagen auch die Beanspruchungen der Konstruktion. Hochleistungsbetone mit selbstverdichtenden Eigenschaften werden in Windenergieanlagen schon seit einiger Zeit zur Herstellung von Verbindungen zwischen den einzelnen Bauteilen verwendet. Darüber hinaus werden derzeit aufgelöste Gründungskonstruktionen und Türme aus Spannbeton, für die hochfester Beton eingesetzt wird, entwickelt. Diese Hochleistungsbetone sind für den Grenzzustand der Ermüdung zu bemessen, was zukünftig nach fib‐Model Code 2010 erfolgen wird. Dieser enthält ein geändertes Ermüdungsbemessungsmodell für Beton, das auch für hochfeste Betone zu sicheren und wirtschaftlichen Bemessungsergebnissen führt. Am Institut für Baustoffe der Leibniz Universität Hannover wird seit Jahren das Ermüdungsverhalten von Hochleistungsbetonen untersucht. Darüber hinaus wird auch der Einfluss von Stahlfasern auf das Ermüdungsverhalten von Hochleistungsbetonen erforscht. In diesem Beitrag werden aktuelle Forschungsergebnisse zum Ermüdungsverhalten verschiedener Hochleistungsbetone mit und ohne Stahlfaserverstärkung vorgestellt und darauf aufbauend der praktische Einsatz dieser Betone diskutiert. Die Ergebnisse der durchgeführten Untersuchungen werden im Kontext zum neuen Ermüdungsbemessungsmodell des fib‐Model Code 2010 interpretiert.Fatigue behaviour of high performance concretes for wind turbinesNew developments in the wind energy sector will lead to wind turbines with enormous capacities. As a result, the loads of the supporting structures are also increasing. For some time now, high performance concretes with self‐compacting properties have been used in wind turbines for structural connections. Furthermore, slender foundations and prestressed concrete supporting structures made out of high‐strength concrete are under development. In future, fatigue design of these high performance concretes is to be done according to the new fib‐Model Code 2010. This code includes a new fatigue design model which enables a safe and economic fatigue design, even for high strength concrete. Extensive research with regard to the fatigue behaviour of different types of high performance concrete has been carried out at the Institute of Building Materials Science, Leibniz Universität Hannover. As part of these research activities, the influences of steel fibre reinforcement on the fatigue behaviour of high performance concretes are being investigated. In this paper, interim results of these investigations are presented and the potential for the practical applications of high performance concrete is discussed. The results of the conducted investigations are presented in comparison with the new fatigue design model of the fib‐Model Code 2010.
Gebäude für Physiotherapie und Medizintechnik der Hochschule Lausitz Senftenberg
Authors: Brensing Christian , Beecken Anja 
Published: August 2012

AbstractFür den eingeschossigen Neubau für Physiotherapie und Medizintechnik der Hochschule Lausitz plante die Architektin aus Kosten‐, energetischen und Zeitgründen das Bauwerk als eine Ständerkonstruktion aus Holzleimbindern. Das äußere Erscheinungsbild des Gebäudes lässt jedoch nicht auf seine Konstruktionsweise schließen. Die äußerst flexible Bauweise der Holzkonstruktion erwies sich als Gewinn, da es während der Planungs‐ und Bauzeit zu zahlreichen Änderungen kam, die entsprechend schnell und effizient umgesetzt werden konnten. Das gesamte Bauwerk, einschließlich des intensiv begrünten Flachdachs, erfüllt höchste energetische Richtlinien.Building of Physiotherapy and Medical Technology at the Lausitz UniversityFor reasons related to cost, time, sustainability and energy performance the architects decided in favour of a single storey building made of prefabricated glulam. However, the elevation of the centre physiotherapy and medical technology of the Lausitz University does not give any clues on its construction. Still the extreme flexible timber construction proved to be an asset as during planning and construction many changes in terms of layout and use had to be made. Due to the type of construction they could be implemented quickly and efficiently. The entire building, including the flat green roof, fulfils some of the highest German standards of energy efficiency.
BÜV‐Empfehlungen für die Überwachung von Windenergieanlagen
Authors: Jäppelt Ulrich , Harte Reinhard 
Published: August 2012

AbstractIn den letzten beiden Jahrzehnten ist der Markt für Windenergieanlagen rasant gewachsen und hat dadurch auch eine dynamische Weiterentwicklung der entsprechenden Technologien ermöglicht.Initiiert durch die Novellierung des Erneuerbare Energien‐Gesetzes sowie durch das Ablaufen der genehmigten Nutzungsdauer bei den Anlagen der Ersten Generation, gewinnt der Ersatz alter Windenergieanlagen zunehmend an Bedeutung. Wachsende Rotordurchmesser und Turmhöhen stellen zudem neue Anforderungen an Tragwerksplaner, Prüfer und Überwacher.Im Beitrag werden Empfehlungen des Bau‐Überwachungsvereins BÜV für die Bauüberwachung und wiederkehrende Prüfung von Windenergieanlagen an Land vorgestellt.BÜV recommendations for supervision of onshore wind energy plantsIn the last two decades, the sector of wind energy plants has grown rapidly and therefore enabled also a dynamic development of relevant technologies.Initiated by revision of the Renewable Energy Law as well as by the expiration of the approved life of first generation plants, the replacement of ancient wind energy plants has gained increasing significance. Increasing rotor diameters and tower heights lead additionally to new demands on structural engineers, checking engineers and supervisors.In the attached text recommendations of the Bau‐Überwachungsverein BÜV regarding site supervision and periodic inspections of onshore wind energy plants are presented.
Die Nacht der Korallen
Authors: Loch Karen , Loch Wolfgang 
Published: August 2012

AbstractDas synchrone Massenlaichen der Steinkorallen ist bei den Malediven ein durch den Klimawandel ausgelöstes Phänomen. An dieser ungeheuer eindrucksvollen sexuellen Reproduktion nimmt ein Großteil aller Geweihkorallenarten der Gattung Acropora teil.
Laparoscopic stapled cardioplasty for failed treatment of achalasia
Authors: Dehn T C B , Slater M , Trudgill N J , Safranek P M , Booth M I 
Published: August 2012

Abstract

Background
Treatment of primary achalasia includes injection of botulinum toxin, pneumatic dilatation or surgical myotomy. All of these procedures have an associated failure rate. Laparoscopic stapled cardioplasty (LSC) may be an alternative to failed pneumatic dilatation and laparoscopic Heller's myotomy where oesophagectomy has previously been the only surgical option.

Methods
Selected patients with recurrent achalasia following multiple failed medical treatments, including myotomies, were managed by LSC. Patients had postoperative contrast swallows before discharge with clinical follow-up.

Results
All seven patients treated with LSC were discharged within 5 days. Rapid oesophageal emptying was noted on all post-LSC contrast swallows. No patient had an anastomotic leak. After 1 year, all but one patient was free from dysphagia, all had gained weight, and four patients had heartburn controlled by a proton pump inhibitor.

Conclusion
LSC may be a useful procedure for resistant achalasia.
EGFR targeting monoclonal antibody combines with an mTOR inhibitor and potentiates tumor inhibition by acting on complementary signaling hubs
Authors: James Roshan , Vishwakarma Siddharth , Chivukula Indira V. , Basavaraj Chetana , Melarkode Ramakrishnan , Montero Enrique , Nair Pradip 
Published: August 2012

AbstractNimotuzumab, an anti‐epidermal growth factor receptor (anti‐EGFR) monoclonal antibody, has been used extensively in many solid tumors and confers significant survival advantage. The antibody has limited skin toxicity and is generally well tolerated. Similar to other anti‐EGFR therapies, patients may relapse a few months after treatment. In this study we show for the first time, the use of Nimotuzumab along with Sirolimus has synergistic effect on tumor inhibition as compared with the drugs used individually, in Nimotuzumab responsive and nonresponsive cell lines. In vitro studies prove that while Sirolimus (25 nmol/L) affects the signal downstream to mammalian target of rapamycin (mTOR), Nimotuzumab (83 nmol/L) downregulates pTYR, pMAPK and pSTAT3 by 40%, 20% and 30%, respectively. The combination, targeting these two different signaling hubs, may be associated with the synergistic inhibition observed. In vivo, the use of half human therapeutic equivalent doses for both the drugs substantially reduces tumors established in nude as well as severe combined immunodeficiency (SCID) mice by EGFR overexpressing A‐431 cells. The drug combination reduces cell proliferation and the expression of signal transduction molecules. Treated tumors are better differentiated as compared with those established in the control mice. Tumor microarray demonstrates that Nimotuzumab and the combination groups segregate independently to the Sirolimus and the control treatment. The combination uniquely downregulated 55% of the altered tumor genes, extending beyond the typical pathways associated with Nimotuzumab and Sirolimus downstream pathways inhibition. These results would suggest that this nontoxic drug combination improves therapeutic benefit even in patients with low‐EGFR expression and severely immunocompromised because of their current medication.
ChemInform Abstract: Phosphine‐Boronates: Efficient Bifunctional Organocatalysts for Michael Addition.
Authors: Basle Olivier , Porcel Susana , Ladeira Sonia , Bouhadir Ghenwa , Bourissou Didier 
Published: August 2012

AbstractThe presence of a Lewis acid boron center adjacent to the phosphine moiety significantly improves the catalytic activity in the Michael addition of malonate pronucleophiles to vinyl ketones.
ChemInform Abstract: Direct Perfluorination of an Acid‐Sensitive Glycol Ether as Precursor for Perfluoro(2‐(methoxymethoxy)ethyl vinyl ether).
Authors: Feng Wen , et al. et al. 
Published: August 2012

AbstractThe liquid‐phase direct fluorination of the acid‐sensitive glycol ether (IV) is achieved by control of the gradient increase of the temperature (‐20 to +15 °C) and addition of sodium fluoride.
ChemInform Abstract: Enantioselective Preparation of cis‐β‐Azidocyclopropane Esters by Cyclopropanation of Azido Alkenes Using a Chiral Dirhodium Catalyst.
Authors: Gu Peiming , Su Yan , Wu Xiu‐Ping , Sun Jian , Liu Wanyi , Xue Ping , Li Rui 
Published: August 2012

AbstractThe process renders possible the synthesis of various conformationally restricted target compounds in a diastereoselective and enantiocontrolled manner.
ChemInform Abstract: Palladium‐Catalyzed One‐Pot Synthesis of Polysubstituted Furans from Alkynoates and 2‐yn‐1‐ols.
Authors: Huang Huawen , Jiang Huanfeng , Cao Hua , Zhao Jinwu , Shi Dabin 
Published: August 2012

AbstractThe regioselectivity of the reaction depends on the behavior of the substrates and the conditions.
ChemInform Abstract: Rh2(OAc)4‐Catalyzed Substrate Selective [4 + 2]/[2 + 2] Cycloaddition of Acylketenes: A Highly Chemo‐ and Regioselective Synthesis of Spiro(oxindolyl)oxazinones and β‐Lactams.
Authors: Reddy B. V. Subba , Karthik Govindaraju , Rajasekaran Tamilselvan , Antony Aneesh , Sridhar B. 
Published: August 2012

AbstractReaction of isatin‐3‐arylimines with acylketenes, generated in situ from 2‐diazoacetylacetone, affords title compounds (III).
ChemInform Abstract: Low Brain Penetrant CB1 Receptor Agonists for the Treatment of Neuropathic Pain.
Authors: Adam Julia M. , et al. et al. 
Published: August 2012

AbstractAmong a variety of indolyl‐oxadiazole and ‐thiadiazole derivatives, compound (Ia) is identified as an orally bioavailable, low brain penetrant CB1 receptor agonist with robust activity in rodent models of neuropathic pain and a good preclinical therapeutic profile, which is selected for clinical development.
ChemInform Abstract: Synthesis of Pyrano[2,3‐c]carbazoles, Pyrano[3,2‐b]carbazoles and Furo[3,2‐b]carbazole Derivatives via Iodocyclization.
Authors: Talluri Krishna Chaitanya , Nagarajan Rajagopal 
Published: August 2012

AbstractA facile synthesis of novel pyranocarbazole derivatives from easily accessible O‐propargylated carbazoles (I) and (III) is presented.
ChemInform Abstract: Microwave‐Assisted One‐Pot Synthesis of Isoquinolines, Furopyridines, and Thienopyridines by Palladium‐Catalyzed Sequential Coupling—Imination—Annulation of 2‐Bromoarylaldehydes with Terminal Acetylenes and Ammonium Acetate.
Authors: Yang Dingqiao , Burugupalli Satvika , Daniel David , Chen Yu 
Published: August 2012

AbstractA wide range of isoquinolines and related heterocyclic systems can be prepared starting from aldehyde substrates.
ChemInform Abstract: Aspergilazine A, a Diketopiperazine Dimer with a Rare N‐1 to C‐6 Linkage, from a Marine‐Derived Fungus Aspergillus taichungensis.
Authors: Cai Shengxin , Kong Xianglan , Wang Wei , Zhou Huinan , Zhu Tianjiao , Li Dehai , Gu Qianqun 
Published: August 2012

Abstractwith a weak activity against influenza A (H1N1) virus
ChemInform Abstract: TMDS as a Dual‐Purpose Reductant in the Regioselective Ring Cleavage of Hexopyranosyl Acetals to Ethers.
Authors: Zhang Yin‐Jie , Dayoub Wissam , Chen Guo‐Rong , Lemaire Marc 
Published: August 2012

Abstract4,6‐O‐Benzylidene or alkylidene glycosyl acetals can be cleaved at the O4‐ or O6‐position under optimized conditions using TMDS and either copper triflate as catalyst or a stoichiometric amount of AlCl3.
Multiple layer design for mass data transmission against channel congestion in IoT
Authors: Liu Yang , Chen Zhikui , Lv Xiaoning , Han Feng 
Published: August 2012

SUMMARYInternet of Things (IoT) is well studied from many aspects; however, data transmission in a large‐scale constructed IoT network is still an open topic. In this paper, the problems of channel congestion caused by mass data transmission are discussed respectively from different perspectives. Then, a multiple layer solution is proposed, pointing to each layer including data processing architecture, data dimension reduction, data abandon protocol, and spectrum sharing. In the architecture layer, a combined scheme with cloud computing and sea computing is introduced. Context awareness and granular computing is exploited to implement the data dimension reduction. And cognitive protocol is involved with type of service, which drops certain data to guarantee the entire network connectivity. Then, a principal–agent theory based two‐step game model is proposed with the consideration of cooperation and price coefficient, which affect the secondary user's choice and primary user's profit. Some incomplete information is assumed as random variables so that certainty equivalent is introduced in the model. A simple scenario shows how the data dimension reduction works and how simulations for data abandon protocol and spectrum sharing test the two parts, respectively. Copyright © 2012 John Wiley & Sons, Ltd.
Reduced predation risk for melanistic pygmy grasshoppers in post‐fire environments
Authors: Karpestam Einat , Merilaita Sami , Forsman Anders 
Published: August 2012

AbstractThe existence of melanistic (black) color forms in many species represents interesting model systems that have played important roles for our understanding of selective processes, evolution of adaptations, and the maintenance of variation. A recent study reported on rapid evolutionary shifts in frequencies of the melanistic forms in replicated populations ofTetrix subulatapygmy grasshoppers; the incidence of the melanistic form was higher in recently burned areas with backgrounds blackened by fire than in nonburned areas, and it declined over time in postfire environments. Here, we tested the hypothesis that the frequency shifts of the black color variant were driven, at least in part, by changes in the selective regime imposed by visual predators. To study detectability of the melanistic form, we presented human “predators” with images of black grasshoppers and samples of the natural habitat on computer screens. We demonstrate that the protective value of black coloration differs between burnt and nonburnt environments and gradually increases in habitats that have been more blackened by fire. These findings support the notion that a black color pattern provides improved protection from visually oriented predators against blackened backgrounds and implicate camouflage and predation as important drivers of fire melanism in pygmy grasshoppers.
A (Diborole)cobalt Complex with a C–H···B Bridge, CpCo(1,3‐C3B2Me5H), and Its Thallium Derivative: Synthesis, Structure, and Bonding
Authors: Muratov Dmitry V. , Romanov Alexander S. , Petrovskii Pavel V. , Antipin Mikhail Yu. , Siebert Walter , Kudinov Alexander R. 
Published: August 2012

AbstractThe reaction of CpCo(1,3‐C3B2Me5H) (1) with CpTl affords the thallium derivative CpCo(1,3‐C3B2Me5)Tl (2). The structures of 1 and 2 were determined by X‐ray diffraction at 100 K. An “extra” hydrogen atom in 1 occupies a C–H···B bridging position. According to DFT calculations, 1 exists as a mixture of two enantiomers with an enantiomerization barrier of only 0.5 kcal mol–1. The transition state has Cs symmetry with an endo‐CH hydrogen atom. The isomeric iso‐1with the Co–H···B bridge is less stable than 1 by 10 kcal mol–1.The formation of 1 and iso‐1 from C3B2Me5H and CpCo(C2H4)2 have almost equal activation energies. The isomerization of iso‐1 to 1 was shown to proceed as a two‐step hydrogen transfer. The bonding of the “extra” hydrogen atom in the related CHB‐bridged carborane nido‐2,3,5‐C3B3R5H2 and metallacarboranes M(C5R5)(C3B2R′5H) (R, R′ = H, Me; M = Co, Rh, Ir) as well as their hydridic isomers MH(C5R5)(C3B2R′5) was compared. According to energy decomposition analysis, the bonding of the parent anion [CpCo(1,3‐C3B2H5)]– with metal cations becomes stronger in the following order: K+ < Na+ < Tl+ < Li+ < [RuCp]+. The attractive interactions between the [CpCo(1,3‐C3B2H5)]– and Tl+ fragments are 68 % electrostatic and 32 % covalent.
Adsorption of [Mn19] Aggregates with S = 83/2 onto HOPG Surfaces
Authors: Ako Ayuk M. , Alam Mohammad Sahabul , Mameri Samir , Lan Yanhua , Hibert Marcel , Stocker Michael , Müller Paul , Anson Christopher E. , Powell Annie K. 
Published: August 2012

AbstractA structural analogue of the previously reported record‐high‐spin (S = 83/2) mixed‐valence [Mn19] coordination cluster [MnIII12MnII7(μ4‐O)8(μ3‐η1‐N3)8(HLMe)12(MeCN)6]Cl2·10MeOH·MeCN (1) {H3LMe = 2,6‐bis(hydroxymethyl)‐4‐methylphenol} was prepared in which the methyl group at the 4‐position on the phenyl ring was replaced by a methoxy group to give the compound [Et3NH]2[MnIII12MnII7(μ4‐O)8(μ3‐η1‐N3)7.4(μ3‐Cl)0.6(HLOMe)12(MeOH)6]Cl4·14MeOH (2). Single‐crystal X‐ray diffraction analysis of 2 confirms that the molecular structure motif found for 1, comprising two supertetrahedral {MnIII6MnII4} units sharing a common MnII vertex, was retained. Magnetic susceptibility measurements on 2 show that the ferromagnetic spin structure, which results in the maximum ST = 83/2 spin ground state for 1, is largely robust with respect to the change in ligand substituent in 2. Molecules of compounds 1 and 2 were deposited onto highly oriented pyrolytic graphite (HOPG) substrates and were investigated by scanning tunneling microscopy (STM) andcurrent imaging tunneling spectroscopy (CITS). By usingextremely dilute solutions (10–9 mol L–1), one‐dimensionalarrangements as well as isolated single molecules of [1]Cl2·10MeOH·MeCN were observed with STM topography, generally at the step edges or at defects of the HOPG surfaces, while small groups of molecules of 2 were observed. The size of the individual molecules was consistent with the X‐ray crystallographic data. In the CITS images of the single molecules, a strong tunneling current contrast was observed at the positions of the metal ions.
Efficient Metal‐Free Organic Sensitizers Containing Tetraphenylethylene Moieties in the Donor Part for Dye‐Sensitized Solar Cells
Authors: Shi Jie , Huang Jing , Tang Runli , Chai Zhaofei , Hua Jianli , Qin Jingui , Li Qianqian , Li Zhen 
Published: August 2012

AbstractTwo new propeller‐shaped D‐π‐A organic sensitizers that contain two tetraphenylethylene (TPE) moieties in the donor part of the triphenylamine group have been designed and characterized. These dyes are composed of the same donor and acceptor units with different aromatic units introduced through linkers between the donor and acceptor units. The dye‐sensitized solar cells (DSCs) based on LI‐31 with 10 mM chenodeoxycholic acid (CDCA) show the best light‐to‐power conversion efficiency of 6.77 % (Jsc = 14.69 mA cm–2; Voc = 0.74 V; fill factor: ff = 0.62) under standard global AM 1.5 solar light conditions (100 mW cm–2).