bluuebunny/crossref_metadata_2025_split huggingface dataset:
129: THE EFFECT OF LAVENDER ESSENTIAL OIL ON VITAL SIGNS (BLOOD PRESSURE, PULSE) IN PATIENTS UNDERGOING CORONARY ANGIOGRAPHY
Authors: yousefi zeynab 
Published: May 2024

Background and aims:common invasive angiography is a diagnostic test that is useful in the diagnosis of cardiovascular disease patients often experience anxiety and increase their vital signs before angiography. The aim of this study was to evaluate the effect of lavender essential oil on hemodynamic parameters in patients before angiography is inhaled.Methods:This study is a randomized clinical trial in which 40 patients scheduled for coronary angiography were involved after obtaining written consent from the patients were divided into two groups. Vital signs of the times before and after the intervention to measure and record Grdyd.sps 16 SPSS software using independent t-test were analyzed.Results:The two groups in demographic and hemodynamic parameters before the intervention, after intervention Ndashtnd.ama significant difference between the two groups in terms of hemodynamically significant difference were observed (p≤0/05).Conclusion:The scent of lavender significantly reduces blood pressure, pulse number of patients.
148: THE STUDY OF SPECIALIST PHYSICIAN KNOWLEDGE AND ATTITUDE OF TELEMEDICINE AND BARRIERS TO ITS IMPLEMENTATION IN TABRIZ TEACHING HOSPITALS
Authors: Miandoab Amir Torab , Alizadeh Ghasem , Rezaei Peyman 
Published: May 2024

Background and aims:By incidence of modern technologies in different areas such as medicine which has been recognized as Telemedicine. This technology can play important role in increases quality level of medical services and health treatments. For successful increase of implementation and development of this technology in Iran needs to provide cultural, legal, political, social and technological atmosphere. Therefore assessing awareness volume of people and their attitude toward telemedicine can be an important factor in accepting this technology which indicated in this research.Methods:This research was done in 2016 with sectional and descriptive study on 676 Professional physician which provide health and treatment services at Tabriz University of Medical Science With random and questionnaire method including 4 sections,, awareness on telemedicine, attitude about telemedicine, utilization of telemedicine and barrier of telemedicine. Services based one extracted replies from completed questioners with SPSS software aid.Results:Awareness of physicians in related to telemedicine is poor, also 45 percent of physicians was use this technology that most usage is relate to phone council service and so from physician opinion's lack of suitable culture for utilization, lack of awareness about this technology and lack of infrastructure are most barriers to utilization from telemedicine.Conclusion:According to the statistics resulted from this research, it is understood that intendancy volume from this technology and its entrance to these hospitals accepted by many peoples. It is expected that it has developmental procedure in its reception and can be used properly with educational schedules and has economic effective benefits.
154: A PHARMACOECONOMIC EVALUATION TO MAKE DECISION: IS THE USE OF SIMVASTATIN 10 MG AS AN OTC MEDICATION COST-EFFECTIVE FOR THE PRIMARY PREVENTION OF STROKE AMONGST WOMEN IN IRAN?
Authors: Amirsadri Mohammadreza , Dorri Niloufar 
Published: May 2024

Background and aims:Cardiovascular disease (CVD) is one of the most important causes of death and disability in Iran. Stroke is a serious cardiovascular situation which poses many problems for both patients and societies. Considering the pleiotropic effects of statins and their safety, particularly in low doses, as well as the increasing trend of stroke in Iranian populations, the economic evaluation techniques were used in this study to support decision-making regarding the use of simvastatin 10mg as an OTC drug for the primary prevention of stroke among women with an average CVD risk in Iran.Methods:A semi-Markov model was developed in this study to investigate both cost-utility (using QALY or Quality-Adjusted-Life-Years) and cost-effectiveness (using LYG or Life-Years-Gained). Different discount rates (0%, 3% and 7.2%) used in various scenario analyses. The time horizon was life-long and the target population was women older than 55 years with average risk CVD (15% for 10 years). Two sensitivity analyses techniques (one-way and probabilistic sensitivity analysis), were applied to test robustness of the results.Results:In the base-case scenario the intervention of getting OTC statin for primary prevention was $9118 per QALY and $19016 per LYG per person with annual discounting rate of 0%.Conclusion:In Iran no threshold has been determined but the results were compared with the threshold that WHO recommended (GDP per capita for Iran is $5442.9 for 2014 by World Bank). Considering this threshold, the evaluated intervention could be considered cost-effective.
178: FORECASTING THE SHORTAGE OF NEUROSURGEONS IN IRAN USING A SYSTEM DYNAMICS MODEL APPROACH
Authors: Ezzatabadi Mohammad Ranjbar , Zadeh Sina Abdollah , Rafiei Sima 
Published: May 2024

Background and aims:Shortage of physicians particularly in specialty levels is considered as an important issue in Iran health system. Thus in an uncertain environment, long term planning is required for health professionals as a basic priority on a national scale.The study aimed to estimate the number of required neurosurgeons using system dynamic modelling.Methods:System dynamic modelling was applied to predict the gap between stock and number of required neurosurgeons in Iran up to 2020. A supply and demand simulation model was constructed for neurosurgeons using system dynamic approach. The demand model included epidemiological, demographic and utilization variables. Along with, supply model incorporated current stock of neurosurgeons and flow variables such as: attrition, migration and retirement rate. Data were obtained from various governmental databases were analysed by Vensim PLE Version 3.0 to address the flow of health professionals, clinical infrastructure, population demographics and disease prevalence during the time.Results:It was forecasted that shortage in number of neurosurgeons would disappear at 2020. The most dominant determinants on predicted number of neurosurgeons were the prevalence of neurosurgical diseases, the rate for service utilization and medical capacity of the region.Conclusion:Results of the study suggests that shortage of neurosurgeons in some areas of the country relates to maldistribution of the specialists. Accordingly there is a need to reconsider the allocation system for health professionals within the country instead of increasing the overall number of acceptance quota in training positions.
186: KNOWLEDGE, SELF-EFFICACY AND PRACTICE REGARDING THE USE OF EVIDENCE-BASED PRACTICE AMONG MIDWIVES IN THE EAST OF IRAN
Authors: Azmoude Elham , Farkhondeh Fereshteh 
Published: May 2024

Background and aims:The use of EBP can provide appropriate and effective care in pregnancy, childbirth and postnatal period. Levels of knowledge and confidence in the ability likely related to implementation of evidence-based care. This study was carried out to investigate the level of midwifery knowledge, self-efficacy and practice toward evidence-based practice in the region east of Iran.Methods:A cross-sectional study was conducted in all midwives of two hospitals and health care centers in Torbat Heydariyeh, Iran in 2016. Survey instruments included the Evidence-Based Practice Questionnaire and self-efficacy in Evidence-Based Practice scale. Descriptive statistics and Pearson and Spearman correlation coefficient were employed to analyze the data.Results:The mean±SD scores of knowledge, self-efficacy and practice to implement EBP were 4.48±0.94, 3.53±0.68 and 2.80±0.81, respectively. A significant relationship were found between knowledge, self-efficacy and practice mean scores with proficiency in English language and statistical methods (p<0.05). Additionally, a highly significant relationship was found between knowledge and practice of midwives and proficiency in the use of databases (p<0.05). The midwives' mean scores in the two subscales of knowledge and self-efficacy was correlated with their scores practice toward EBP (P<0.05).Conclusion:This survey has shown the need to improve knowledge, self-efficacy and practice to assist in employing evidence based practice. Interventions that consider the relevant factors have been identified in this study, may help to increase knowledge, self-efficacy and practice regarding EBP.
194: ROLE OF INFORMATION IN PREVENTION OF UNNECESSARY HEALTH DELIVERY
Authors: Vangari Vishwa Mohan 
Published: May 2024

Health is real wealth. Ill-health disables normalcy in one's life, therefore, health delivery proves to be indispensable and invaluable. But at the same time unnecessary health delivery proves to be harmful and costly. In modern times the cost of health delivery is so heavy that people belonging to lower economic strata cannot afford it. When this is the situation, unnecessary health delivery proves to be unethical. It is in view of this Right information at the right time would play a vital role in preventing unnecessary health delivery, that in turn would prevent physical damage caused to the person and also save substantial amount of money. The study aims at exploring how information plays a role in preventing unnecessary health delivery.The methodology applied to carry out the study was a mix-method of quantitative analysis and qualitative study on a cohort group of 10 patients who had chronic ailments for more than 10 years. The data was collected through a clinical interview with an unstructured schedule consisting of open-ended questions.The study identified four categories for direct impact of information in control of unnecessary health delivery including cost, hospital readmission diagnostic test prescription, and reduction in drug/medication prescription. In addition, almost all (90%) respondents fully agreed to the vital role of information in preventing unnecessary health delivery. All the respondents (100%) emphasis that the information should flow through authentic sources. Most of the respondents state that professional ethics and integrity occupy primary place in avoiding unnecessary health delivery.
25: ASSOCIATION OF SERUM GAMMA- INTERFERON AND IL-10 CONCENTRATIONS WITH INSULIN RESISTANCE IN MAJOR THALASSEMIA PATIENTS
Authors: Jahromi Abdolreza Sotoodeh , Rahmanian Zhila 
Published: May 2024

Background and aims:Thalassemia is one of the most prevalent hematologic disorders worldwide. Thalassemia is the most common inherited anemia and genetic disease. Diabetes mellitus and insulin resistance is one of the major endocrine problems in major thalassemia patients. This study was done to evaluate the association of serum γ- interferon and IL-10 concentrations with insulin resistance in splenectomized and non-splenectomized major thalassemia patients.Methods:193 thalassemia patients with rang of years old participated in this study. IFN-γ and IL-10 levels were measured using ELISA method. Insulin resistance was measured using HOMA-IR method. Data was analyzed with SPSS software by Pair T test.Results:the mean age of splenectomized patients in this study was 8.86±7.03 and non- splenectomized patients 7.88±2.39 years. There were significant and inverse associations between serum IL-10 levels and insulin resistance was found in non-splenectomized major thalassemia patients (P=0.002). There were not a significant association between serum IL-10 levels and insulin resistance in splenectomized major thalassemia patients (P=0.079). There were not a significant association between serum γ- interferon levels and insulin resistance in splenectomized major thalassemia patients (P=0.778). There were not significant associations between serum γ- interferon levels and insulin resistance in non- splenectomized major thalassemia patients (P=0.435).Conclusion:In this study, interferon-gamma as an inflammatory cytokine and interlukin-10 as an anti-inflammatory cytokines was studied. Overall these results suggest that interleukin-10 is associated with insulin resistance in non-splenectomized major thalassemia patients and as an anti-inflammatory cytokine may play an important role in sustaining insulin resistance in non-splenectomized major thalassemia patients. With increase in serum IL-10 levels there is a decline in insulin resistance. This data provide new insights into the mechanisms of insulin resistance and support the use of other cytokines with insuln resistance in major thalassemia patients.
28: CAN PHTHALATES DISRUPT OOCYTE MEIOTIC MATURATION IN MOUSE MODEL?
Authors: Absalan Forouzan 
Published: May 2024

Background and aims:Phthalates, which are commonly used to render plastics into soft and flexible materials, have also determined as developmental and reproductive toxicants in human and animals. The purpose of this study was to evaluate the effect of mono-(2-ethylhexyl) phthalate (MEHP) and di-(2-ethylhexyl) phthalate (DEHP) oral administration on maturation of mouse oocytes, apoptosis and gene transcription levels.Methods:Immature oocytes recovered from NMRI mouse strain (6–8 weeks) were divided into seven different experimental and control groups. Control group oocytes were retrieved from mice that received only normal saline. Experimental groups I, II or III oocytes were retrieved from mice treated with 50, 100 or 200 µl DEHP (2.56 µM) solution, respectively. Experimental groups IV, V or VI oocytes were retrieved from mouse exposed to 50, 100 or 200 µl MEHP (2.56 µM) solution, respectively. Fertilization and embryonic development were carried out in OMM and T6 medium. Apoptosis was assessed by annexin V-FITC/Dead Cell Apoptosis Kit with PI staining. In addition, the mRNA levels ofPou5f1,Ccna1andAsah1were examined in oocytes.Results:The proportion of oocytes that progressed up to metaphase II (MII) and 2-cells embryo formation stage was significantly decreased by exposure to MEHP or DEHP, in a dose related pattern. Annexin V and PI positive oocytes showed greater quantity in treated mice than control. Quantitative RT-PCR revealed that expression levels ofPou5f1,Asah1andCcna1were significantly lower in treated mouse oocytes than control.Conclusion:These results indicate that oral administration of MEHP and DEHP could negatively affect mouse oocyte meiotic maturation and developmentin vivo, suggesting that phthalates could be risk factors for mammalians' reproductive health. Phthalate-induced changes inPou5f1,Asah1andCcna1transcription level explain in part the reduced developmental ability of mouse-treated oocytes.
36: COMPARISON OF SIDE EFFECTS IN TWO METHODS OF ENDOTRACHEAL SUCTIONING (OPEN AND CLOSED) IN PREMATURE INFANTS UNDER MECHANICAL VENTILATION
Authors: Janani Raheleh , Jannatdoost Abdollah , Seyedrasuli Alehe , Valizadeh Leila , Sarbakhsh Parvin 
Published: May 2024

Background and aims:Endo tracheal suctioning is a common neonatal intensive care procedure that is performed to clear trachea bronchial airways of secretions and maintain patency of the endotracheal tube in intubated infants, which may lead to complications. Two systems are available to perform ES: open suction system and closed suction system. Since bacterial airway colonization, nosocomial pneumonia, and septicemia are important issues in neonatal care, recent study aims to compare side effects in two methods of endotracheal suctioning (open and closed) in premature infants under mechanical ventilation.Methods:In current clinical trial study, 90 preterm infants of (27–34 weeks of GA) hospitalized in NICUs of Alzahra and Taleghani Teaching hospitals, (2014), elected and randomly assigned to two groups. One group was suctioned by open suctioning method and the other by closed suctioning method. However frequency of suctioning and side effects as pulmonary hemorrhage, IVH, pneumothorax, pneumonia and septicemia until extubation and duration of hospitalization were investigated and compared. Data analysis was performed using SPSS (ver. 21) and descriptive and analytic statistical methods such as x2 and independent T test analysis.Results:Overall, there was no significant statistical difference on frequency of suctioning and side effects as pulmonary hemorrhage, IVH, pneumothorax, pneumonia and septicemia until extubation and duration of hospitalization. But all side effects and mortality rate were higher in open suction.Conclusion:Evidence indicates that, there was no significant statistical difference on frequency of suctioning, side effects and duration of hospitalization. Considering clinical significance with regard to Evidenc-Based Clinical Decision Making, it is recommended that a comprehensive study over a greater population of premature infants should be carried out.
5: A SURVEY ON INFORMATION DERIVATION TECHNIQUES OF POST-GRADUATE STUDENT OF TABRIZ UNIVERSITY OF MEDICAL SCIENCE IN 2015
Authors: Sohrabi Zahra-Sadat , Gavgani Vahideh Zarea 
Published: May 2024

Background and aims:The purpose of this study was to identify the information derivation techniques of medical and allied health sciences' postgraduate students.Methods:The study was a cross sectional descriptive survey. The data was collected from Tabriz University of Medical Sciences' student using a structured questionnaire. Data was analyzed using descriptive statistics and T-test through SPSS 16.Results:Total of 300 questionnaire were collected that 178(59.3%) of them were female students and 122 (40.7%) male. Out of 300, number of 160 (53.3%) were studding in M.Sc. level and 140 (46.7%) were doctoral students. Findings of study showed that the most significant motivation of students for searching information was continuing education in the higher levels, finding answer for the course assignments and projects. Academic publishing were the other considerable reasons for information search and retrieval. Searching information via general search engines like Google with (70.7%) and book with (50.3%) were the most used formal information resources by students. The most considerable limitation for accessing information was numerated as low speed Internet/networks, and internet disconnection (59.7%), subscription discontinuing with some of databases (47%).Conclusion:The study did not find differences between male and female students information seeking skills. The students' attitudes towards using databases and search tools were different among M.Sc. and Doctoral students. There were no statistically significant differences between the students' educational level and their aim for information searching as well as the educational level and the limitations they face in searching information. The biggest complaint of students was the speed of internet connection in all level, and access to core databases. Therefore it is suggested to promote the internet connection speed and access at least in university campus.
61: EVIDENCE BASE NURSING PRACTICE: A CROSS SECTIONAL STUDY IN SOUTH OF IRAN
Authors: Khammarnia Mohammad , Mohammadi Mahsa Haj , Amani Zahra , Rezaeian Shahab , Setoodehzadeh Fatemeh 
Published: May 2024

Background and aims:This study aimed to determine the barriers to implementation of EBP among nurses.Methods:This cross-sectional study was conducted in Zahedan City, South East of Iran, in 2014. The questionnaire of barriers to implementation of EBP consists of 27 statements which were distributed among 280 nurses.Results:More than half of the participants agreed that 56% and 57% of barriers to implementation of evidence based practice are related to organizational and individual aspects, respectively. Participants identified barriers at organizational level included the lack of human resources (78.3%), lack of internet access at work (72.2%), and heavy workload (70.0%). Barrier at individual level included lack of time to read literature (83.7%), lack of ability to work with computer (68.8%), and insufficient proficiency in English language (62.0%). Age, educational level, job experience, and employment status were associated with organizational barriers to implementation of EBP. At the individual level only education was associated with barriers to implementation of EBP.Conclusion:Barriers to implementation of EBP occur at both individual and organizational levels. The indicator of quality in nursing practice is EBP. Hence, familiarity with EBP is recommended for Iranian nurses. In addition, knowledge of barriers will help health care system and policy makers to provide a culture of EBP.
63: EVIDENCE BASED PRACTICAL GUIDELINE FOR THE MANAGEMENT OF MAJOR HEMORRHAGE IN CHILDREN AND TEENAGERS
Authors: Shahriari Mahdi 
Published: May 2024

Background and aims:Management of major hemorrhage in any setting requires a multidisciplinary approach. The aim of this guideline is to provide recommendations for the hematological management of major hemorrhage in any clinical situation, with practical guidance for Clinical Hematologists and laboratory staff on the content and delivery of major bleeding protocols, including the use of blood components and transfusion alternatives. These updated guidelines are based on new studies, which have provoked reassessment of the principles of managing major hemorrhage in all clinical situations, and which mandate much closer working between hospital blood banks and emergency departments to provide timely transfusion support for patients with major bleeding.Methods:The writing group was Pediatric hematologists-Oncologists who were transfusion and hemostasis experts, and consultation with the Trauma, Anesthesiologists, Obstetric-Gynecologists, Hematopathologists and critical care was made. Relevant systematic reviews were identified by searching PubMed and Embase using the term “bleeding” and “hemorrhage” combined with “management”, “trials”, “children” and “teenagers”. The search covered articles published up until April 2016. Only human studies were included and articles not written in English were excluded. The quality of evidence was judged by predefined Grades of Recommendation, Assessment, Development and Evaluation (GRADE) criteria.Results:Definition of major hemorrhage: Standard definitions are not particularly helpful because they are retrospective. Our arbitrary definition of major hemorrhage is bleeding which leads to a heart rate more than 110 beats/ min and/or systolic blood pressure less than 90 mmHg for teenagers and less than third percentile for age in children. Early recognition of significant blood loss, ideally before major increments in pulse rate and falls in blood pressure, will allow prompt action to pre-empt shock.Conclusion:Medical, nursing and midwifery staff involved in frontline care must be trained to recognize major blood loss early, know when to activate the local major hemorrhage protocol and take prompt and appropriate action (1D). Annual workshops for continuous medical education are highly suggested.