bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure and Photosynthetic Mimicking of Bis (2,6‐bis (benzimidazol‐2‐yl) pyridine) manganese (II)
Authors: Wei Shi , Wei Li , Ying‐Kai Xu , Hong‐Mei Wang , Mei Shi , Yang Liu , Ping‐Ping Shen 
Published: September 2010

AbstractMn(bzimpy)2(1) [bzimpy = 2, 6‐bis (benzimidazol‐2‐yl) pyridine], a mononuclear manganese (IT) complex, was synthesized by the reaction of Mn (OOCMe)2 with bzimpy in absolute ethanol. The complex was structurally characterized by elemental analysis, cyclic voltammetry, and X‐ray crystallography. In the complex, the manganese‐nitrogen distances were different, and the geometry and the metal ion environment showed the distortion. The cyclic voltammetric measurements have been performed to assess its redox characteristics. The presence of oxidation wave at + 0.62 V and + 0.81 V vs. SCE or + 0.8 V and + 1.0 V vs. NHE suggested that this complex could catalyze the oxidation of water, therefore, simulate the water‐oxidizing complex (WOC) of photosystem II (PS II). The measurements of photoreduction of 2, 6‐dichlorophenolindophenol (DCPIP), and oxygen evolution in the manganese‐depleted and the complex 1‐reconstituted PS II preparations just support our conjecture.
Fabrication, Characterization and Electrocatalysis of an Ordered Carbon Nanotube Electrode
Authors: Jing Chen , Jian‐Chun Bao , Chen‐Xin Cai 
Published: September 2010

AbstractA method for fabrication of the ordered carbon nanotube (CNT) film, which was template‐synthesized within the highly ordered pores of a commercially available alumina template membrane, modified glassy carbon (CNT/GC) electrode was established. The CNT/GC electrode showed excellent electro‐catalytic activity toward dopamine electrochemical reaction without introducing any electrochemically active group into CNT film or activating the electrode electrochemically. DA undergoes ideal reversible electrochemical reaction on CNT/GC electrode at low scan rate (≤20 mV/s) with an excellent reproducibility and stability. The CNT/GC electrode might be used in biosensors because the highly ordered CNT may present a steric effect on more efficient redox reactions of biomolecules.
Clean Synthesis in Water: Darzens Condensation Reaction of Aromatic Aldehydes with Phenacyl Chloride
Authors: Da‐Qing Shi , Shu Zhang , Qi‐Ya Zhuang , Xiang‐Shan Wang , Shu‐Jiang Tu , Hong‐Wen Hu 
Published: September 2010

AbstractThe Darzens condensation reaction of aromatic aldehydes with phenacyl chloride proceeded very efficiently in a water suspension medium in the presence of triethylbenzylammonium chloride and only trans‐2, 3‐epoxy‐l, 3‐diaryl‐l‐propanones were formed which can be isolated simply by filtration. The structures of these compounds were confirmed by elemental analysis, IR and 1H NMR spectra. Their configurations are in agreement with that of the same compounds reported in the literature. Compared to the classical Darzens condensation, this new method has the advantages of good yields, high stereoselectivity, low running cost inexpensive and environmentally benign procedure.
Anodic Stripping Voltammetric Determination of Lead (II) Using Glassy Carbon Electrode Modified with Novel Calix[4]arene
Authors: Jian‐Quan Lüu , Xi‐Wen He , Xian‐Shun Zeng , Hai‐Li Zhang , Zheng‐Zhi Zhang 
Published: September 2010

AbstractA new glassy carbon electrode modified with novel calix[4]‐arene derivative was prepared and then applied to the selective recognition of lead ion in aqueous media by cyclic and square wave voltammetry. A new anodic stripping peak at − 0.92 V (vs. Ag/Ag+) in square wave voltammogram can be obtained by scanning the potential from − 1.5 to − 0.6 V, of which the peak current is proportional to the concentration of Pb2+. The modified electrode in 0.1 mol/L HNO3 solution showed a linear voltammetric response in the range of 2.0 × 10–8–1.0 × 10–6 mol/L and a detection limit of 6.1 × 10–9 mol/L. In the modified glassy carbon electrode no significant interference occurred from alkali, alkaline and transition metal ions except Hg2+, Ag+ and Cu2+ ions, which can be eliminated by the addition of KSCN. The proposed method was successfully applied to determine lead in aqueous samples.
Synthesis of Dendritic Schiff Base Ligands for Titanium Catalyzed Enantioselective HDA Reaction of Danishelfsky's Diene with Aldehydes
Authors: Ji Bao‐Ming , Ding Kui‐Ling , Meng Ji‐Ben 
Published: September 2010

AbstractA new type of dendritic NOBIN derived Schiff base ligands has been synthesized and applied to titanium catalyzed hetero‐Diels‐Alder reaction of Danishelfsky's diene and aldehydes, affording the corresponding 2‐substituted 2,3‐dihydro‐4H‐pyran‐4‐one in good yields and moderate enantioselectivities (up to 59.2% ee). It was found that the size of dendron attached to the tri‐dentated ligands has slight impact on the enantioselectivity of the reaction and the second generation of dendritic ligand exhibited the best enantioselectivity.
Study on the Aggregation and Deaggregation Behaviors of Phosphatidylcholines
Authors: Ji Guo‐Zhen , Long Ya‐Qiu , Jiang Xi‐Kui 
Published: September 2010

AbstractPhosphatidylcholines and their analogs, the functional building block of the membrane, are recently found to mediate multiple physiological processes and exhibit a broad range of desirable pharmacological effects, which involve hydrophobic lipophilic interactions (HLI) between the phospholipid and the cell membrane. The HLI behavior of phosphatidylcholines (Ln) and their analogues 1, 2‐diacyl‐sn‐glycerol‐3‐phosphoric acid bromoethyl ester (Pn), have been investigated in MeOH‐H2O binary systems of different volume fractions (designated as ϕ) of the organic component, by employing α‐nephthylethyl lauryl ether (Np‐12) as fluorescent probe. A very interesting observation is that the Ln possesses double character, i.e., it behaves both as an aggregator and as a deaggregator. The effects of the structure and the environment on the coaggregation and deaggregation are also discussed.
Self‐assembly of Novel Hetero[3]rotaxane, [2]Rotaxanes and [2]Catenane
Authors: Zhang Wei‐Xing , Fan Cui‐Qin , Tu Bo , Zhao Xin , Jiang Xi‐Kui , Li Zhan‐Ting 
Published: September 2010

AbstractOne linear template 13 and one cyclophane template 15, both incorporating two electron rich 1,4‐dialkoxybenzene units and one diamide unit, have been synthesized. By utilizing donor‐acceptor interaction and/or intermolecular hydrogen bonding assembling principles, one novel hetero[3]rotazane 22·4Cl, possessing one neutral and one tetracationic ring components, has been synthesized from 13, through neutral [2]rotaxane 21 as intermediate. With 15 as template, tetracationic [2]catenane 23·4PF6 was assembled by using donor‐acceptor interaction, but no neutral [2]rotaxane could be obtained under the typical conditions of hydrogen bonding assembling principle. The interlocked supramolecular compounds have been characterized and their spectral properties are investigated.
Synthesis and Spectroscopic Characterizations of an Insulinomimetic Peroxovanadate Complex in Aqueous Solution
Authors: Cai Shu‐Hui , Yu Xian‐Yong , Chen Zhong , Wan Hui‐Lin 
Published: September 2010

AbstractThe reaction system of diperoxooxalatovanadate {K3[VO(O2)2‐(C2O4)]·H2O, bpV(Oxa)} and imidazole was studied in an aqueous solution by ID multinuclear (1H, 13C and 51V) NMR, 2D NMR diffusion ordered spectroscopy (DOSY), and variable temperature NMR techniques. It was shown that DOSY was a useful tool for the study of a mixture. All of the 1H and 13C NMR signals of the peroxovanadate (V) complexes were assigned. The NMR experimental results indicated that a new complex was formed through the coordination interactions between bpV(Oxa) and imidazole. The newly‐formed complex is stable under the experimental condition. Electrospray ionization mass spectrometry (ESI‐MS) provides positive evidence to support the conclusion.
Direct Electrochemistry of Horseradish Peroxidase Embedded in Nano‐Fe3O4Matrix on Paraffin Impregnated Graphite Electrode and Its Electrochemical Catalysis for H2O2
Authors: Gong Jing‐Ming , Lin Xiang‐Qin 
Published: September 2010

AbstractFe3O4particles coated with acrylic copolymer (ACP) of about 5–8 nm in diameter were synthesized and used for immobilization of horseradish peroxidase (HRP). Direct electrochemistry of HRP embedded in the nanosized Fe3O4solid matrix modified paraffin impregnated graphite electrode (PIGE) was achieved, which is related to the heme Fe(III)/Fe(II) conversion of HRP. Cyclic voltammetry gave a pair of reproducible and well‐defined redox peaks at aboutEmof‐0.295 V vs. SCE. The standard rate constantk2was determined as 2.7 s−1. It demonstrated that the nano‐Fe3O4solid matrix offers a friendly platform to assemble the HRP protein molecules and enhance the electron transfer rate between the HRP and the electrode. UV‐Vis absorption spectra and FTIR spectra studies revealed that the embedded HRP retained its native‐like structure. The HRP/Fe3O4/PIGE showed a strong catalytic activity toward H2O2. The voltammetric response was a linear function of H2O2concentration in the range of 10–140 μmol/L with detection limit of 7.3 μmol/L (s/n= 3). The apparent Michaelis‐Menten constant is calculated to be 0.42 mmol/L.
Structural Effect on Eu(fod)3‐Catalyzed Rearrangement of Allylic Esters
Authors: Dai Wei‐Min , Mak Wing‐Leung 
Published: September 2010

AbstractA detail study on the Eu(fod)3‐catalyzed rearrangement of allylic esters was described. A significant effect of the substituents at the allylic backbone was observed. The migrating tendency of the alkoxyacetates was established in the order of p‐CF3C6H4CH2OCH2CO2 > MeOCH2CO2 > PhCH2OCH2CO2 > p‐MeOC6H4CH2OCH2CO2.
A Facile Synthetic Method for the Preparation of s̀‐Symmetric (1, 2:4, 5)‐Diepoxypentane Equivalent
Authors: Jiang Biao , Chen Zi‐Li , Shen Min , Wang Zhi‐Min , Shi Min 
Published: September 2010

AbstractOptically active s̀‐symmetric (1, 2:4, 5)‐diepoxypentane equivalent (10) has been synthesized in eight steps with moderate yields and diastereomeric excess by using Sharpless asymmetric dihydroxylation (AD reaction). Compound 10 can be used to prepare syn 1,3‐diol subunit in natural product.
A New Approach to the Asymmetric Reaction of the Chiron 5‐L‐Menthyloxy‐2(5H)‐furanones with Horner‐Emmons Reagent
Authors: Li Xue‐Qiang , Wang Feng‐Rong , He Lan , Chen Qing‐Hua 
Published: September 2010

AbstractThe asymmetric reaction of the chiron 2(5H)‐furanones (4a–4c) with the Horner‐Emmons reagents (5a—5b) has been investigated. The newly chiral organophosphorus derivatives 6 and 7 were obtained using the phosphoryl‐stabilized carbanion as a building block in DMSO under mild conditions. Through the asymmetric introduction, the Horner‐Emmons reagent could be transformed to a chiral building block to afford the novel functionalized phosphorus derivatives. The structures of the synthesized compounds 6 and 7 were identified on the basis of their elementary and spectroscopic data, such as IR, 1H NMR, 13C NMR, MS and X‐ray crystallography. These results provided a valuable approach to the synthesis of potentially interesting chiral organophosphorus derivatives and probing their biological activities.
Syntheses of Two Potential Ligands for Tc‐99m Labeling as Diagnosis Agents of Alzheimer's Disease
Authors: Zhuang Zhi‐Ping , Kung Mei‐Ping , Ono Masahiro , Hou Catherine , Kung Hank F. 
Published: September 2010

AbstractTwo types of ligands‐biphenyl and stilbene derivatives, which can be labeled with Tc‐99m for the diagnosis of Alzheimer's disease (AD) have been synthesized successfully. The key steps in these two syntheses involved Suzuki reaction and Wittig reaction respectively. The new discovered debromination reaction may be expanded to the compounds with double or triple bond adjacent to the carbon atom bearing the bromine atoms. These types of syntheses provide a route to a series of biphenyl and stilbene derivatives that will benefit the search of new imaging agents for AD.
Cleavage of the Fe–Fe Bond of (Me2SiSiMe2)[η5‐C5H4Fe (CO)2]2 with Na/Hg and Molecular Structure of the Ring‐Opened Complex
Authors: Sun Hud‐Lin , Zhang Zhen‐Sheng , Zhou Xiu‐Zhong 
Published: September 2010

AbstractThe reaction of the title cyclic complex (1) with sodium amalgam in THF resulted in the expected cleavage of the Fe—Fe bond to afford bis‐sodium salt (Me2SiSiMe2) [η5‐C5H4Fe (CO)2Na]2 (4). The latter was not isolated and was used directly to react with MeI, PhCH2Cl, CH3C(O)Cl, PhC(O)Cl, Cy3SnCl (Cy = cyclohexyl) or Ph3SnCl to afford corresponding ring‐opened derivatives (Me2SiSiMe2) [η5‐C5H4Fe (CO)3R]2 [5, R=Me; 6, R = PhCH2; 7, R = CH3C(O); 8, R = PhC (O); 9, R = Cy3Sn or 10, R = Ph3Sn]. The crystal and molecular structures of 10 were determined by X‐ray diffraction analysis. The molecule took the desired anti conformation around the Si—Si bond. The length of the Si—Si bond is 0.2343(3) nm, which is essentially identical to that in the cyclic structure of 1 [0.2346(4) nm]. This result unambiguously demonstrates that the Si—Si bond in the cyclic structure of 1 is not subject to obvious ring strain.
Study on Synthesis of Multivalent Neoglycoproteins and Their Binding Properties to Hepatic Stellate Cells
Authors: Zhang Jian , Zhang Qi‐Sheng , Tian Geng‐Yuan 
Published: September 2010

AbstractNeoglycoproteins of human serum albumin (HSA) modified with some kind of carbohydrates were synthesized. Their molecular weight and purification were determined by HPSEC and SDS‐PAGE, respectively. The binding properties of these conjugates to hepatic stellate cells (HSCs) were evaluated by confocal fluorescence microscopy. The bioactivity revealed that compound 4a (HSA modified with glucose) showed high binding affinity.
Syntheses and Crystal Structure of Six‐coordinated Diorgnotin Complexes with 2, 5‐Dimercapto‐4‐phenyl‐1, 3,4‐thiodiazoIe
Authors: Ma Chun‐Lin , Li Feng , Zhang Ru‐Fen , Wang Da‐Qi 
Published: September 2010

AbstractThe reactions of diorganotin dichloride [Ph2SnCl2, (PhCH2)2‐SnCl2 or (n‐Bu)2SnCl2] with potassium salt of 2, 5‐dimercapto‐4‐phenyl‐1, 3, 4‐thiodiazole gave complexes R2Sn (S3N2C8H5)2 (4: R = Ph; 5: R = PhCH2 and 6: R = n‐Bu), respectively. Characterizations were carried out for all complexes by IR, 1H NMR spectra and X‐ray crystallography analysis. Including the Sn…︁N interaction, the three complexes all have six‐coordinated distorted octahedral geometry. Based on the requence of stereochemical constraint sequence, phenyl≈benzyl > n‐butyl, the less the effect of the stereochemical constraint of R groups, the shorter the Sn…︁N length. In complexes 5 and 6, there exist S…︁S weak intra‐molecular interactions, through which the complexes are dissociated into loose 2D polymers. All three complexes show antitumour activity in bioactivity measurements.
Lipase‐Catalyzed Resolutions of both Enantiomers of Ornidazole and Secnidazole
Authors: Tian Ping , Peng Jia‐Shi , Li Zu‐Yi , Lin Guo‐Qiang 
Published: September 2010

AbstractThe resolutions of both enantiomers of the ornidazole and secnidazole were achieved with high enantiomeric excesses (ee > 99%) by acylation of the corresponding racemates with vinylacetate in the presence of lipase Amano AK (from Pseudomonas sp.). The assignments of the absolute configurations of (+) or (‐)‐ornidazole and secnidazole are described.
Structural Features of Fructans from the Root of Cyathula officinalis Kuan
Authors: Chen Xiao‐Ming , Tian Geng‐Yuan 
Published: September 2010

AbstractThree fructans (CoPS1, CoPS2 and CoPS3) were isolated from the root of Cyathula officinalis Kuan, a traditional Chinese medicine. The structures of the fructans were determined by methylation, reductive‐cleavage method combined with GC‐MS analysis, and 13C NMR spectroscopy. These results show that the fructans (CoPS1, CoPS2 and CoPS3) are graminan type fructans, and comprised of (2→1)‐and (2→6)‐linked β‐D‐fructofuranosyl backbone residues containing high branches.
Application of Pac Ester in Thioester Method for the Synthesis of Cyclopentapeptides
Authors: Liu Mian , Tian Gui‐Ling , Ye Yun‐Hua 
Published: September 2010

AbstractThioester method for the synthesis of cyclopeptides is improved by using Pac (Pac = phenacyl, CH2COC6H5) ester as a protecting group of 3‐mercaptopropionic acid. The Pac group is easy to be removed from C‐terminal with zinc in acetic acid. The protected glycine thioester and peptide thioesters synthesized by the improved method, are easy to be purified, so the final linear peptides are pure enough for the following cyclization. Furthermore, this method is flexible for peptide chain elongation, either from C‐terminal or from N‐terminal. So it is an efficient and practical method for synthesis of bioactive peptides. Two N‐protected pentapeptide thioesters, Boc‐Pro‐Tyr‐Leu‐Ala‐GlySCH2CH2COOPac and Boc‐Ala‐Tyr‐Leu‐Ala‐Gly‐SCH2CH2‐COOPac were synthesized by the improved thioester method. After deprotecting Pac ester with zinc in aqueous acetic acid and Boc group with trifluoroacetic acid in CH2Cl2, two free pentapeptide thioesters were obtained. Ag+‐assisted cyclization in acetate buffered solution afforded two cyclic pentapeptides c(Pro‐Tyr‐Leu‐Ala‐Gly) and c(Ala‐Tyr‐Leu‐Ala‐Gly). Effects of different buffer pH, different Ag+ concentrations, etc. on the cyclization were studied.
Alkylation of Sulfur Ligand in Cysteinate‐Iron Chelates by a 1,2,4, 5‐Tetraoxane
Authors: Liu He‐Hua , Wu Yi‐Kang , Shen Xin 
Published: September 2010

AbstractReaction of a 1, 2, 4, 5‐tetraoxane with cysteinate‐iron in the presence of excess methyl cysteinate led to formation of sulfuralkylated methyl cysteinate in 33% yield, illustrating a possible mechanism for tetraoxanes'antimalarial action.
Catalytic Asymmetric [2, 3]‐Sigmatropic Rearrangement of Sulfur Ylides Generated from Carbenoids and Allenic 2‐Methylphenyl Sulfide
Authors: Zhang Xiao‐Mei , Ma Ming , Wang Jian‐Bo 
Published: September 2010

AbstractThe first investigation on catalytic asymmetric [2, 3]‐sigmatropic rearrangement of sulfur ylides generated from carbenoids and allenic phenyl sulfide was carried out. Up to 55% ee value was obtained.
Enhancive Synthesis of ‐lβ, 11‐Diol‐4‐en‐eudesmol
Authors: Chen Jin‐Chun , Zheng Guo‐Jun , Zhang Chen , Fang Li‐Jing , Li Yu‐Lin 
Published: September 2010

AbstractAn enhancive synthesis of −1β, 11‐diol‐4‐en‐eudesmol, starting from 2‐chloroacrylonitrile, is described. The effect of temperature on the Diels‐Alder reaction of 2‐chloroacrylonitrile with 2‐methylfuran and the condition of cationic cyclization of diene were discussed in detail.
Consecutive Reaction of Bis [2, 2, 2‐trifluoroethyl] phosphite. One‐pot Synthesis of Substituted 3‐Cyano‐β, γ‐unsaturated Nitriles with Exclusive or Predominant E‐Selectivity
Authors: Shen Yan‐Chang , Zhang Yu‐Ming 
Published: September 2010

AbstractThe consecutive reaction of bis [2, 2, 2‐trifluoroethyl] phosphite and its application to the one‐pot synthesis of 3‐cyano‐β, γ‐unsaturated nitriles with exclusive or predominant E‐selectivity (E:Z = 100–85:0—IS) and excellent yields (94%—99%) are described.
SmI2‐Mediated Addition Reaction of α‐Halomethylsulfones to Carbonyl Compounds. A Convenient Synthesis of β‐Hydroxysulfones
Authors: Huang Xian , Duan De‐Hui , Jin Hong‐Wei 
Published: September 2010

AbstractDue to the chemoselective dehalogenation by SmI2, the addition of α‐halomethylsulfones to carbonyl compounds afforded β‐hydroxysulfones. Those reactions with α‐bromomethylsulfones gave the products in moderate to good yields. The SmI2‐mediated addition of gem‐dihalomethylsulfones to ketones also afforded α‐halo‐β‐hydroxysulfones in moderate yields.
Synthesis and Characterization of a Novel Perfluorinated Ionomer Polymer Containing Sulfonimide Functionality
Authors: Zhu Shi‐Zheng , Zhang Yun‐Xiang , Jin Gui‐Fang , Desmarteau Darryl D. 
Published: September 2010

AbstractThe novel perfluorinated vinyl ether containing sulfonimide functionality CF2= CFOR1SO2NHSO2CF3was synthesized by multiple reaction steps. It could be copolymerized with tetrafluoroethylene by radox initiator to give a novel perfluorinated ionomer polymer. Its physical and chemical properties were studied.
Two New Lignans from Taxus yunnanensis
Authors: Li Sheng‐Hong , Zhang Hong‐Jie , Yao Ping , Niu Xue‐Mei , Xiang Wei , Sun Han‐Dong 
Published: September 2010

AbstractThe phytochemical investigation on the ethanolic extracts of the barks of Taxus yunnanensis (Taxaceae) led to the isolation of two new neo‐lignans, named taxuyunins A (1) and B (2), a‐long with the known diterpenolignan, brevitaxin (3). Their structures were elucidated on the basis of spectroscopic and chemical evidences. Compound 1 is a neo‐lignan xyloside while compound 2 belongs to the rare neo‐lignan possessing a ramified C3side chain.
Synthesis of a New Cerebroside Isolated from Typhonium giganteum Engl
Authors: Chen Xue‐Song , Wu Yu‐Lin , Chen Di‐Hua 
Published: September 2010

AbstractThe stereoselective synthesis of typhoniside, a new cerebroside isolated from Typhonium giganteum Engl, was accomplished. Cerebrosides are a kind of glycolipids highly enriched on the surface of myelin‐producing cells and are composed by C18–4, 8‐sphingadienine, α‐hydroxy acid and a saccharide head. It was the first time that cerebrosides were isolated from this traditional Chinese medicine (TCM) by us. In this paper, C18–4, 8‐sphingadienine was synthesized from D‐xylose via a SN2 type reaction, α‐Hydroxy acid was prepared from (R)‐4‐hydroxyte‐trahydrofuran‐2‐one, which in turn could be obtained from L‐ascorbic acid.
Molecular Recognition of Bridged Bis(β‐cyclodextrin) s Linked by Phenylenediseleno Tether on the Primary or Secondary Side with Fluorescent Dyes
Authors: Li Li , He Song , Liu Yu 
Published: September 2010

AbstractA novel β‐cyclodextrin dimer, 2, 2′‐o‐phenylenediseleno‐bridged bis (β‐cyclodextrin) (2), has been synthesized by reaction of mono‐[2‐O‐(p‐tolylsulfonyl)]‐β‐cyclodextrin and poly(o‐phenylenediselenide). The complexation stability constants (K2) and Gibbs free energy changes (‐ΔG°) of dimer 2 with four fluorescence dyes, that is, ammonium 8‐anilino‐1‐naphthalenesulfonate (ANS), sodium 6‐(p‐toluidino)‐2‐naphthalenesulfonate (TNS), Acridine Red (AR) and Rhodamine B (RhB) have been determined in aqueous phosphate buffer solution (pH = 7.2, 0.1 mol‐L−1) at 25 °C by means of fluorescence spectroscopy. Using the present results and the previously reported corresponding data of β‐cyclodextrin (1) and 6, 6′‐o‐phenylenediseleno‐bridged bis (β‐cyclodextrin) (3), binding ability and molecular selectivity are compared, indicating that the bis (β‐cyclodextrin)s 2 and 3 possess much higher binding ability toward these dye molecules than parent β‐cyclodextrin 1, but the complex stability constant for 2 linked from the primary side is larger than that of 3 linked from the secondary side, which is attributed to the more effective cooperative binding of two hydrophobic cavities of host 3 and the size/shape‐fit relationship between host and guest. The binding constant (K2,) upon inclusion complexation of host 3 and AR is enhanced by factor of 27.3 as compared with that of 1. The 2D 1H NOESY spectrum of host 2 and RhB is performed to confirm the binding mode and explain the relative weak binding ability of 2.
A Concise Synthesis of Monoterpene Pyridine Alkaloid Aucubinine B
Authors: Yang Xiao‐Xia , Zhao Jing‐Rui , Jia Xue‐Shun , Yang Li‐Wei , Zhai Hong‐Bin 
Published: September 2010

AbstractAucubinine B (4), a monoterpene alkaloid obtained from the metabolites of aucubin in the presence of human intestinal bacteria, has been synthesized from 3‐bromo‐4‐pyridinecarboxaldehyde (5) in four steps with 39% overall yield. The construction of the cyclopenta[c]pyridine intermediate (7) was realized by an intramolecular Heck reaction.
Remarkably Accelerated Regioselective Hydrogenolysis of Terminal Epoxides in the Presence of CoCl2 or NiSO4
Authors: Shen Xin , Chao‐Jun Tang. , Wu Yi‐Kang 
Published: September 2010

AbstractThe rate of atmospheric pressure hydrogenolysis of terminal epoxides over palladium‐charcoal to the corresponding methyl alcohols could be remarkably accelerated by introduction of CoCl2 or NiSO4.