bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health‐related quality of life of US adults with arthritis: Analysis of data from the behavioral risk factor surveillance system, 2003, 2005, and 2007
Authors: Furner Sylvia E. , Hootman Jennifer M. , Helmick Charles G. , Bolen Julie , Zack Matthew M. 
Published: April 2011

AbstractObjectiveTo describe the health‐related quality of life (HRQOL) of persons with and without arthritis in the 50 US states and the District of Columbia, and to determine correlates of poor HRQOL in persons with arthritis.MethodsData from the Behavioral Risk Factor Surveillance System were used. Descriptive analyses were age standardized and multivariate analyses used logistic regression.ResultsOf persons ages ≥18 years with arthritis, 27% reported fair/poor health, compared to 12% without arthritis. The mean numbers of physically unhealthy, mentally unhealthy, and activity‐limited days for persons with arthritis exceeded those for persons without arthritis. In regression analyses, black non‐Hispanics reported better HRQOL than white non‐Hispanics, especially in the ≥14 versus 0 days comparisons. Yet no difference existed in self‐reported health status between these two groups. Having a low family income and being unable to work were both strongly associated with poor HRQOL. Being physically active was associated with better HRQOL. Binge drinking was associated with poor HRQOL for some measures, but was associated with better self‐reported health. Cost being a barrier to care and having diabetes mellitus were strongly associated with worse HRQOL.ConclusionAdults from the US with arthritis had worse HRQOL than those without. Physical health and mental health were both affected by arthritis; therefore, efforts to alleviate the arthritis burden should address both domains. Given the current and projected high prevalence of arthritis, we face a significant burden of poor HRQOL. Increasing physical activity, reducing comorbidities, and increasing access to health care could improve the HRQOL of persons with arthritis.
Painting by Numbers: Nanoparticle‐Based Colorants in the Post‐Empirical Age
Authors: Taylor Robin Klupp , Seifrt Frantisek , Zhuromskyy Oleksandr , Peschel Ulf , Leugering Günter , Peukert Wolfgang 
Published: April 2011

AbstractThe visual appearance of the artificial world is largely governed by films or composites containing particles with at least one dimension smaller than a micron. Over the past century and a half, the optical properties of such materials have been scrutinized and a broad range of colorant products, based mostly on empirical microstructural improvements, developed. With the advent of advanced synthetic approaches capable of tailoring particle shape, size and composition on the nanoscale, the question of what is the optimum particle for a certain optical property can no longer be answered solely by experimentation. Instead, new and improved computational approaches are required to invert the structure‐function relationship. This progress report reviews the development in our understanding of this relationship and indicates recent examples of how theoretical design is taking an ever increasingly important role in the search for enhanced or multifunctional colorants.
Orale, direkte Thrombin‐ und Faktor‐Xa‐Hemmer: Kommt die Ablösung für Warfarin, Blutegel und Schweinedärme?
Authors: Straub Alexander , Roehrig Susanne , Hillisch Alexander 
Published: April 2011

AbstractBislang müssen sich Patienten zur Vorbeugung von Thrombosen nach Operationen täglich Heparin spritzen oder müssen zur Schlaganfallprophylaxe bei Vorhofflimmern Vitamin‐K‐Antagonisten vom Cumarintyp einnehmen, die eine geringe therapeutische Breite haben und deren Dosierung regelmäßig überwacht werden muss. Um den Therapiestandard bei thromboembolischen Erkrankungen, wie tiefen Venenthrombosen, Lungenembolien und Hirnschlag bei Vorhofflimmern, zu verbessern, wurde in der letzten Dekade intensiv an neuen, oral wirksamen Thrombin‐ und Faktor‐Xa‐Inhibitoren geforscht. Einige dieser Verbindungen sind bereits auf dem Markt oder befinden sich in fortgeschrittener klinischer Entwicklung; sie könnten den Antikoagulantienmarkt revolutionieren.
Synthesis, characterization, anti‐inflammatory and analgesic activity of transition metal complexes of 3‐[1‐(2‐hydroxyphenyl) ethylideamino]‐2‐phenyl‐3,4‐dihydroquinazolin‐4(3H)‐one
Authors: Hunoor Rekha S. , Patil Basavaraj R. , Badiger Dayananda S. , Vadavi Ramesh S. , Gudasi Kalagouda B. , Chandrashekhar V. M. , Muchchandi I. S. 
Published: April 2011

AbstractA new quinazolinone derivative, 3‐[1‐(2‐hydroxyphenyl)ethylideamino]‐2‐phenyl‐3,4‐dihydroquinazolin‐4(3H)‐one (LH) was synthesized by the condensation of 2‐hydroxyacetophenone‐2‐aminobenzoylhydrazone and benzaldehyde. The cyclization to form 1,2‐dihydroquinazolinone was confirmed by IR, 1D and 2D HETCOR studies. Coordination compounds of Co(II), Ni(II), Cu(II) and Zn(II) of LH were synthesized and characterized using various physico‐chemical studies like stoichiometric, conductivity, magnetic moment measurements and spectral techniques such as IR, NMR, UV‐vis and EPR spectroscopy. The elemental analysis and thermal studies suggested a general stoichiometry [M(HEPDQ)Cl] for all the complexes. A four‐coordinate geometry was assigned to all the complexes. The complexes along with the parent ligand were screened for their anti‐inflammatory activity, using carrageenan‐induced rat paw edema, and for their analgesic activity by Eddy's hot plate method. The activity of the ligand was enhanced on complexation with metal ions. This enhanced activity was attributed to the increased lipophilic nature of the complexes. Notable anti‐inflammatory activity was observed for Ni(II), Cu(II) and Zn(II) complexes. The analgesic activity of the ligand was greater than the standard at 60 min. and at a 10 mg kg−1 dose, whereas the activity of Ni(II) and Cu(II) complexes at 10 mg kg−1 dose was comparable with the standard used. Copyright © 2011 John Wiley & Sons, Ltd.
Modeling of a multizone gas‐phase polyethylene reactor with a cluster‐based approach
Authors: Adli H. , Mostoufi N. , Ghafelebashi S. M. 
Published: April 2011

AbstractA circulating fluidized reactor of polyethylene was modeled with the proper hydrodynamics for a riser and downer and combined with a kinetic model based on the moment equations. The hydrodynamic model was able to predict the profiles of the following parameters through the riser and downer: cluster velocity, bed porosity, concentration of potential active sites, active sites, gas‐phase components, molecular weights, and reactor temperature. It was shown that one could control the monomer consumption and molecular weight, which are crucial in the reactor behavior and production properties, respectively, by setting different operating hydrodynamic conditions, such as the gas velocity in the riser and the solid circulation rate. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Application of glycidol in synthesis of oligoetherols with perhydro‐1,3,5‐triazine ring
Authors: Cyzio Karina , Lubczak Jacek 
Published: April 2011

AbstractA new method of preparation of oligoetherols containing perhydro‐1,3,5‐triazine rings from isocyanuric acid and an excess of glycidol, alkylene carbonates, or oxiranes is presented. The course of reaction was studied at various molar ratios of glycidol to isocyanuric acid. The structure of the products was established, and some physical properties were measured. The oligoetherols were demonstrated to be useful substrates for polyurethane foams of enhanced thermal stability. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Birth, life and death of nascent polypeptide chains
Authors: Jha Sujata , Komar Anton A. 
Published: April 2011

AbstractThe journey of nascent polypeptides from synthesis at the peptidyl transferase center of the ribosome (“birth”) to full function (“maturity”) involves multiple interactions, constraints, modifications and folding events. Each step of this journey impacts the ultimate expression level and functional capacity of the translated protein. It has become clear that the kinetics of protein translation is predominantly modulated by synonymous codon usage along the mRNA, and that this provides an active mechanism for coordinating the synthesis, maturation and folding of nascent polypeptides. Multiple quality control systems ensure that proteins achieve their native, functional form. Unproductive co‐translational folding intermediates that arise during protein synthesis may undergo enhanced interaction with components of these systems, such as chaperones, and/or be subjects of co‐translational degradation (“death”). This review provides an overview of our current understanding of the complex co‐translational events that accompany the synthesis, maturation, folding and degradation of nascent polypeptide chains.
Corporate Carbon Strategies in Responding to Climate Change
Authors: Lee Su‐Yol 
Published: April 2011

ABSTRACTWith climate change emerging as one of the most important issues affecting the business circle, companies have begun considering the carbon issue in their overall strategic positioning. However, few studies have examined the corporate carbon strategies in developing and advanced developing countries, where climate change regulation is extensive and market uncertainty is relatively high. In addition, there has been growing interest among researchers and practitioners concerning the relationship between the carbon strategy and firm performance. This paper presents a framework for identifying the corporate carbon strategy. The cluster analysis of 241 Korean companies indicates six types of corporate carbon strategy: ‘wait‐and‐see observer’, ‘cautious reducer’, ‘product enhancer’, ‘all‐round enhancer’, ‘emergent explorer’ and ‘all‐round explorer’. This study empirically examines whether there are differences between these carbon strategy types in terms of the sector, firm size and firm performance. The results indicate a significant relationship between a firm's carbon strategy and its sector and size but a significant relationship between the carbon strategy and firm performance is not confirmed. Copyright © 2011 John Wiley & Sons, Ltd and ERP Environment.
Assembly of DNA Triangles Mediated by Perylene Bisimide Caps
Authors: Menacher Florian , Stepanenko Vladimir , Würthner Frank , Wagenknecht Hans‐Achim 
Published: April 2011

AbstractPerylene bisimides (PBI) have been synthetically incorporated as caps onto a Y‐shaped DNA triple strand. These PBI caps serve as “sticky” ends in the spontaneous assembly of larger DNA ensembles, linking the triangular DNA through stacking interactions. This, in turn, yields a hypsochromic shift in the absorption and a red shift in the fluorescence as characteristic optical readouts. This assembly occurs spontaneously without any enzymatic ligation process and without the use of overhanging DNA as sticky ends. Instead, dimerizations of the PBI chromophores in the assembly are controlled by the DNA as a structural scaffold. Thereby, the PBI‐driven assembly is fully reversible. Due to the fact that PBI dimerization does not occur in the single strand, the aggregates can be destroyed by thermal dehybridization of the DNA scaffold and reassembled by reannealing of the DNA construct. In view of the fact that PBI forms stable radical anions, the presented DNA architectures are not only interesting optical biomaterials, but are also promising materials for molecular electronics with DNA.
Direct asymmetric N‐specific reaction of nitrosobenzene with aldehydes catalyzed by a chiral primary amine‐based organocatalyst
Authors: Qin Long , Li Lei , Yi Lei , Da Chao‐Shan , Zhou Yi‐Feng 
Published: April 2011

AbstractNitroso compounds have two reactive nitrogen and oxygen atoms. It is interesting and important to perform a nitrogen or oxygen selective reaction with interesting substrates. These atom specific reactions are crucial to specifically synthesis of specific compounds. An enantioselective N‐specific reaction of nitrosobenzene with unmodified aldehydes was successfully achieved catalyzed first by a variety of primary amine‐based organocatalysts with higher yield and enantioselectivity. The bulkier substituted groups of the organocatalyst and two hydrogen bonds from the organocatalyst and the oxygen atom of nitrosobenzene make the reaction preferentially N‐specific and predominantly afford R products. Chirality, 2011. © 2011 Wiley‐Liss, Inc.
A QoS‐aware exception handling method in scientific workflow execution
Authors: Qi Lianyong , Lin Wenmin , Dou Wanchun , Jiang Jian , Chen Jinjun 
Published: April 2011

AbstractScientific workflow is gaining ever‐increasing attention as it integrates a wide range of heterogeneous services to enable and accelerate the scientific discovery processes. However, the exception occurred in a scientific workflow execution often decreases the robustness of a scientific workflow system. For example, if a service engaged in a scientific workflow schedule becomes unavailable during its execution, an exception might be raised and the whole workflow execution may be interrupted unexpectedly. In this situation, it is a challenge to smooth the interrupted workflow execution. In view of this challenge, an exception handling method, named RelaxingMe (constraints Relaxing Method, RelaxingMe) is proposed in this paper. This method aims at relaxing the original QoS constraint values requested by the interrupted task node, in order to find a near‐to‐optimal candidate service to replace the unavailable one. At last, the feasibility of our method is evaluated by an experiment. Copyright © 2011 John Wiley & Sons, Ltd.
The ASSL approach to specifying self‐managing embedded systems
Authors: Vassev Emil , Hinchey Mike 
Published: April 2011

SUMMARYThe increasing complexity of contemporary embedded computing systems requires the use of self‐management in order to handle unforeseen changes in both hardware and control software. The idea behind computer systems capable of self‐management is a complex concept compound by many aspects related to both artificial intelligence and awareness. Here, the biggest challenge is still the question how to properly develop and verify such systems. In this paper, we present a formal approach to specifying embedded systems capable of self‐management. In our approach, we use the ASSL (autonomic system specification language) framework as a development environment, where self‐management features of embedded systems are specified and an implementation is automatically generated. ASSL exposes a rich set of specification constructs that help developers specify event‐driven embedded systems. Hardware is sensed via special metrics intended to drive events and self‐management policies that help the system handle critical situations in an autonomous reactive manner. We present this approach along with a simulation case study where ASSL is used to develop control software for the wide‐angle camera carried on board NASA's Voyager II Spacecraft. Copyright © 2011 John Wiley & Sons, Ltd.
Preparation and optical properties of AgGaS2 nanofilms
Authors: Zhang Jianjun , Huang Yi 
Published: April 2011

AbstractIn this paper, AgGaS2 nanofilms have been prepared by a two‐step process involving the successive ionic layer absorption and reaction (SILAR) and annealing method. Using AgNO3, GaCl3 and Na2S2O3 as reaction sources, the mixture films were firstly deposited on quartz glass substrates at room temperature, and then annealed in Ar environment at 200–500 °C for 4 h, respectively. The effects of annealing temperature on structural and optical properties were investigated by XRD, UV‐Vis, EDS and photoluminescence (PL) spectra. It was revealed in XRD results that α‐Ag9GaS6 was contained in the samples annealed at 200 °C, and this phase was decreased with increase of the annealing temperatures. When the sample was annealed at above 400 °C, the chalcopyrite AgGaS2 nanofilm was obtained. The preferred orientation was exhibited along the (112) plane. It was shown in atomic force microscopy (AFM) results that the grain sizes in AgGaS2 nanofilms were 18‐24 nm and the thin films were smooth and strongly adherent to the substrates. When the annealing temperature was higher than 400 °C, it is an optimum condition to improve the structural and optical properties of the AgGaS2 thin films. The room temperature PL spectra of AgGaS2 nanofilms showed prominent band edge emission at 2.72 eV. Based on all results mentioned above, it can be concluded that the SILAR‐annealing method is preferable to preparing high‐quality AgGaS2 nanofilms. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Electrochemical performance of B and M phases VO2 nanoflowers
Authors: Ni Juan , Jiang Wentao , Yu Ke , Sun Fang , Zhu Ziqiang 
Published: April 2011

AbstractVO2 exists in four phases, among which, the M/R phase VO2 is well known for its reversible metal‐semiconductor phase transition at about 68 °C, and VO2 (B) is a promising candidate cathode material to be applied in aqueous lithium‐ion battery owing to its proper electrode potential and layered structure. In this study, VO2 (B) nanoflowers was synthesized via one‐step hydrothermal process and then successfully transformed into the VO2 (M) by heat treatment. Electrochemical behaviors of the two samples were evaluated by cycling discharge and cyclic voltammetry (CV). The results showed that flower‐like VO2 (B) had the first discharge capacity of 180.33 mAhg‐1, an outstanding value of 52.8% for the capacity retention after 50 cycles. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Quantifying nuclear p65 as a parameter for NF‐κB activation: Correlation between ImageStream cytometry, microscopy, and Western blot
Authors: Maguire Orla , Collins Christine , O'Loughlin Kieran , Miecznikowski Jeffrey , Minderman Hans 
Published: April 2011

AbstractThe nuclear factor kappa B (NF‐κB) pathway, which regulates many cellular processes including proliferation, apoptosis, and survival, has emerged as an important therapeutic target in cancer. Activation of the NF‐κB transcription factor is associated with nuclear translocation of the p65 component of the complex. Conventional methods employed to determine nuclear translocation of NF‐κB either lack statistical robustness (microscopy) or the ability to discern heterogeneity within the sampled populations (Western blotting and Gel Shift assays). The ImageStream platform combines the high image content information of microscopy with the high throughput and multiparameter analysis of flow cytometry which overcomes the aforementioned limitations of conventional assays. It is demonstrated that ImageStream assessment of receptor‐mediated (TNFα) and drug (Daunorubicin, DNR)‐induced NF‐κB translocation in leukemic cell lines correlates well with microscopy analysis and Western blot analysis. It is further demonstrated that ImageStream cytometry enables quantitative assessment of p65 translocation in immunophenotypically defined subpopulations; and that this assessment is highly reproducible. It is also demonstrated that, quantitatively, the DNR‐induced nuclear translocation of NF‐κB correlates well with a biological response (apoptosis). We conclude that the ImageStream has the potential to be a powerful tool to evaluate NF‐κB /p65 activity as a determinant of response to therapies designed to target aberrant NF‐κB signaling activities. © 2011 International Society for Advancement of Cytometry
A genetic algorithm for the uncapacitated facility location problem
Authors: Tohyama Hiroaki , Ida Kenichi , Matsueda Jun 
Published: April 2011

AbstractThe Uncapacitated Facility Location Problem (UFLP) is a fundamental optimization problem involving the selection of locations at which facilities supplying the same service are to be placed. Since it has been shown that the UFLP is NP‐hard, it has generally been thought that there is no hope of finding a polynomial time algorithm by which an optimal solution is always obtained. In this paper, we propose a genetic algorithm for solving the UFLP. In the UFLP, according to the ratio of the cost of facility placement and the cost to users of the facility, the number of facility locations can be roughly estimated. Therefore, partial solution spaces that are likely to contain a good solution can be predicted to some extent on the basis of the classification index. By using mutation with the operation that searches the solution space that is likely to contain a good solution, the proposed method can search the whole space of solutions efficiently. Its effectiveness is shown by a numerical experiment in which our method is compared with existing methods. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(5): 47–54, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10180
Coherent control of semiconductor quantum wire by high‐resolution and stable Michelson interferometer
Authors: Okada Takumi , Komori Kazuhiro , Wang Xue‐Lun , Ogura Mutsuo , Tsurumachi Noriaki 
Published: April 2011

AbstractWe developed a high‐resolution Michelson interferometer in order to stabilize the relative phase of double pulses by using a He‐Ne two‐frequency laser positioning system. A very stable phase‐locked pulse pair whose phase difference was only 4° at 900 nm was realized. Using a high‐resolution Michelson interferometer, we demonstrated coherent control of an exciton in a GaAs/AlGaAs crescent‐shaped quantum wire. The dephasing time of the single quantum wire was 400 fs. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(5): 25–32, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10238
Brain activity when reading sentences and emoticons: an fMRI study of verbal and nonverbal communication
Authors: Yuasa Masahide , Saito Keiichi , Mukawa Naoki 
Published: April 2011

AbstractIn this paper, we describe a person's brain activity when he or she sees an emoticon at the end of a sentence. An emoticon consists of some characters that resemble the human face and expresses the sender's emotions. With the help of a computer network, we use e‐mail, messaging, avatars, and so on, in order to communicate with a recipient. Moreover, we send an emotional expression by using an emoticon at the end of a sentence. In this research, we investigate the effect of an emoticon as nonverbal information, using an fMRI study. The experimental results show that the right and left inferior frontal gyrus were activated and we detect a sentence with an emoticon as the verbal and nonverbal information. © 2011 Wiley Periodicals, Inc. Electron Comm Jpn, 94(5): 17–24, 2011; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/ecj.10311