bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopic endonasal transpterygoid nasopharyngectomy
Authors: Al‐Sheibani Salma , Zanation Adam M. , Carrau Ricardo L. , Prevedello Daniel M. , Prokopakis Emmanuel P. , McLaughlin Nancy , Snyderman Carl H. , Kassam Amin B. 
Published: July 2011

AbstractObjective:Describe our technique for endoscopic transpterygoid nasopharyngectomy and support its feasibility with our early clinical outcomes.Methods:Our endoscopic technique comprises an extended inferomedial maxillectomy, mobilization of the pterygopalatine fossa, removal of the pterygoid plates and Eustachian tube to access the posterolateral nasopharynx. Control of the parapharyngeal and petrous segments of the internal carotid artery is the keystone of the approach.Results:Various histopathologies were treated, including epidermoid carcinomas (n = 9), lymphoepithelioma (n = 1), adenoid cystic carcinoma (n = 5), adenocarcinoma (n = 2), mucoepidermoid carcinoma (n = 2), and sarcoma (n = 1). Negative microscopic margins were obtained in 95% (19/20) of patients. No perioperative mortality, cerebral spinal fluid (CSF) leak, meningitis, or cerebrovascular accident was encountered; however, one patient suffered an internal carotid artery (ICA) injury, without permanent sequelae. All but one patient received adjuvant therapy (external and/or stereotactic radiotherapy with or without chemotherapy). Follow‐up ranged from 15 to 68 months (mean = 33). Overall survival was 45% (9/20) and local control was 65% (13/20).Conclusions:Endoscopic transpterygoid nasopharyngectomy for primary and recurrent nasopharyngeal malignancies is feasible and safe in properly selected patients. Preliminary outcomes compare to that of conventional techniques. Endoscopic resections, however, are demanding; they require specialized equipment and a team versed in endoscopic oncologic surgery. Long‐term follow‐up and reproducibility remain undefined.
Olfactory groove meningioma: Discussion of clinical presentation and surgical outcomes following excision via the subcranial approach
Authors: Pepper Jon‐Paul , Hecht Sarah L. , Gebarski Stephen S. , Lin Erin M. , Sullivan Stephen E. , Marentette Lawrence J. 
Published: July 2011

AbstractObjectives/Hypothesis:To describe surgical outcomes and radiographic features of olfactory groove meningiomas treated by excision through the subcranial approach. Special emphasis is placed on paranasal sinus and orbit involvement.Study Design:Retrospective review of a series of patients.Methods:Nineteen patients underwent excision of olfactory groove meningioma (OGM) via the transglabellar/subcranial approach between December 1995 and November 2009. Nine patients had previously undergone prior resection at outside institutions, and four had prior radiotherapy in addition to a prior excision. Transglabellar/subcranial surgical approach to the anterior skull base was performed.Results:Tumor histology included three World Health Organization (WHO) grade III lesions, one WHO grade II lesion, and 15 WHO grade I lesions. Fourteen patients had evidence of extension into the paranasal sinuses, with the ethmoid sinus being most commonly involved. Kaplan‐Meier estimates of mean overall and disease‐free survival were 121.45 months and 93.03 months, respectively. The mean follow‐up interval was 41.0 months, and at the time of data analysis three patients had recurrent tumors. Seven (36.8%) patients experienced a major complication in the perioperative period; there were no perioperative mortalities. Orbit invasion was observed in four patients, with optic nerve impingement in 11 patients. Of these, three patients had long‐term diplopia. No patients experienced worsening of preoperative visual acuity.Conclusions:Olfactory groove meningiomas demonstrate a propensity to spread into the paranasal sinuses, particularly in recurrent cases. Given a tendency for infiltrative recurrence along the skull base, this disease represents an important area of collaboration between neurosurgery and otolaryngology. The subcranial approach offers excellent surgical access for excision, particularly for recurrences that involve the paranasal sinuses and optic apparatus.
Can maximum urethral closure pressure (MUCP) Be used to predict outcome of surgical treatment of stress urinary incontinence?
Authors: Harris Neil , Swithinbank Lucy , Hayek Samih al , Yang Qian , Abrams Paul 
Published: July 2011

AbstractAimsThe outcome of surgery for stress urinary incontinence (SUI) can be unpredictable. Urethral pressure measurements, including measurement of maximum urethral closure pressure (MUCP) can form part of the investigation of women prior to SUI surgery and some studies have suggested that women with higher MUCP may have a better surgical outcome. This study aims to determine whether outcome of SUI surgery is related to pre‐operative MUCP.MethodsAll patients undergoing colposuspension or TVT in a large European city between 1998 and 2002 were included. All women underwent pre‐operative urodynamics, including measurement of urethral pressure profile; urodynamic data, including MUCP, were determined. Surgical outcome was measured using the ICIQ‐FLUTS questionnaire, which was mailed to allow for a minimum follow‐up period of 3 years. Surgical outcome was measured by assigning patients to one of three post‐operative Stress Urinary Incontinence (SUI) groups. Group 1 (No incontinence), Group 2 (< 1 incontinence episode per day), Group 3 (> 1 incontinence episode per day). Independent statistical analysis was undertaken using STATA® software and a two‐way ANOVA (Analysis of Variance) test to determine the relationship between pre‐operative MUCP and post‐operative SUI group.ResultsA total of 463 postal questionnaires were mailed, with a response rate of 62%, allowing for those who had died or moved away. Of the 285 responders, 218 had undergone colposuspension and 66 had a TVT. Median age, length of follow up and MUCP were 54 years (range 23–81), 77 months (range 47 to 107) and 45 cmH2O (range 5 to 105) respectively. Difference in MUCP between the two operation groups (colposuspension and TVT) was not significant (p > 0.19). No significant difference in preoperative MUCP was demonstrated between the three SUI groups, with mean MUCP in the three SUI groups of 50, 45 and 43 cmH20 respectively, confirming that patients with higher MUCP were not more likely to be in a lower post‐operative SUI group (F(2, 237) = 3.42, p < 0.04).ConclusionOur data demonstrate that women with higher preoperative MUCP do not have a better surgical outcome following stress incontinence surgery. Neurourol. Urodynam. Neurourol. Urodynam. 30: 1609–1612, 2011. © 2011 Wiley Periodicals, Inc.
Moderators of cancer‐related distress and worry after a pancreatic cancer genetic counseling and screening intervention
Authors: Hart Stacey L. , Torbit Lindsey A. , Crangle Cassandra J. , Esplen Mary Jane , Holter Spring , Semotiuk Kara , Borgida Ayelet , Ardiles Paola , Rothenmund Heidi , Gallinger Steve 
Published: July 2011

AbstractObjectivesAlthough the hereditary breast and ovarian cancer literature has demonstrated short‐term gains in psychological adjustment following genetic counseling, there has been limited research examining long‐term outcomes and moderators. Moreover, there has been minimal research into the psychological effects of this intervention in populations at high risk for pancreatic cancer. This study examines the long‐term effects of pancreatic cancer screening and genetic counseling on cancer‐related distress and cancer worry in a high‐risk population at 1‐year follow‐up. Additionally, this study explores potential moderators of the effectiveness of this intervention.MethodsOne hundred twenty‐nine participants with familial pancreatic cancer or with the BRCA2 gene mutation completed a baseline questionnaire prior to their first pancreatic cancer screening and genetic counseling session. Participants also completed questionnaires at 3‐ and 12‐month follow‐up.ResultsCancer‐related intrusive thoughts decreased significantly over time, whereas cancer‐related worry decreased at 3 months and showed a small but significant increase at 1 year. Age and baseline distress exhibited moderator effects. Younger individuals showed a significant decrease in cancer‐related intrusive thoughts, cancer‐related avoidant thoughts, and cancer worry. Additionally, individuals with greater baseline distress showed a significant decrease in cancer‐related intrusive thoughts over time.ConclusionsAnalysis of the long‐term effects of pancreatic cancer screening and genetic testing reveal psychological gains that are maintained at 1‐year follow‐up. This intervention is particularly effective for younger participants and individuals with greater baseline distress. Copyright © 2011 John Wiley & Sons, Ltd.
Brain region‐selective cellular redistribution of mGlu5 but not GABAB receptors following methamphetamine‐induced associative learning
Authors: Herrold Amy A. , Voigt Robin M. , Napier T. Celeste 
Published: July 2011

AbstractAlterations in receptor expression and distribution between cell surface and cytoplasm are means by which psychostimulants regulate neurotransmission. Metabotropic glutamate receptor group I, subtype 5 (mGluR5) and GABAB receptors (GABABR) are critically involved in the development and expression of stimulant‐induced behaviors, including conditioned place preference (CPP), an index of drug‐seeking. However, it is not known if psychostimulant‐induced CPP alters the trafficking of these receptors. To fill this gap, this study used methamphetamine (Meth)‐induced CPP in rats to ascertain if receptor changes occur in limbic brain regions that regulate drug‐seeking, the medial prefrontal cortex (mPFC), nucleus accumbens (NAc), and ventral pallidum (VP). To do so, ex vivo tissue was assessed for changes in expression and surface vs. intracellular distribution of mGluR5 and GABABRs. There was a decrease in the surface to intracellular ratio of mGluR5 in the mPFC in Meth‐conditioned rats, commensurate with an increase in intracellular levels. mGluR5 levels in the NAc or the VP were unaltered. There were no changes for GABABR in any brain region assayed. This ex vivo snapshot of metabotropic glutamate and GABA receptor cellular distribution following induction of Meth‐induced CPP is the first report to determine if these receptors are differentially altered after Meth‐induced CPP. The results suggest that this Meth treatment paradigm likely induced a compensatory change in mGluR5 surface to intracellular ratio such that the surface remains unaltered while an increase in intracellular protein occurred. Synapse, 2011. © 2011 Wiley‐Liss, Inc.
A translucent display algorithm for G‐octree represented grey‐scale images
Authors: Mao Xiaoyang , Fujishiro Issei , Kunii Tosiyasu L. 
Published: July 2011

AbstractA new translucent display algorithm is proposed for grey‐scale images represented by G‐octrees. The algorithm generates a special triangle quadtree as the display image for the isometric projection of a G‐octree, while traversing the G‐octree from front to back, with respect to the viewpoint. A method of using the translucent effect to analyse the interiors of three‐dimensional objects is also described, together with its implementation results.
Polymorphism in Alkali Metal Uranyl Nitrates: Synthesis and Crystal Structure of γ‐K(UO2)(NO3)3
Authors: Jouffret Laurent J. , Krivovichev Sergey V. , Burns Peter C. 
Published: July 2011

AbstractSingle crystals of γ‐K(UO2)(NO3)3 were prepared from aqueous solutions by evaporation. The crystal structure [orthorhombic, Pbca (61), a = 9.2559(3) Å, b = 12.1753(3) Å, c = 15.8076(5) Å, V = 1781.41(9) Å3, Z = 8] was determined by direct methods and refined to R1 = 0.0267 on the basis of 3657 unique observed reflections. The structure is composed of isolated anionic uranyl trinitrate units, [(UO2)(NO3)3]–, that are linked through eleven‐coordinated K+ cations. Both known polymorphs of K(UO2)(NO3)3 (α‐ and γ‐phases) can be considered as based upon sheets of isolated complex [(UO2)(NO3)3]– ions separated by K+ cations. The existence of polymorphism in the two K[UO2(NO3)3] polymorphs is due to the different packing modes of uranyl trinitrate clusters that adopt the same two‐dimensional but different three‐dimensional arrangements.
The adult galactosemic phenotype
Authors: Waisbren Susan E. , Potter Nancy L. , Gordon Catherine M. , Green Robert C. , Greenstein Patricia , Gubbels Cynthia S. , Rubio‐Gozalbo Estela , Schomer Donald , Welt Corrine , Anastasoaie Vera , D'Anna Kali , Gentile Jennifer , Guo Chao‐Yu , Hecht Leah , Jackson Roberta , Jansma Bernadette M. , Li Yijun , Lip Va , Miller David T. , Murray Michael , Power Leslie , Quinn Nicolle , Rohr Frances , Shen Yiping , Skinder‐Meredith Amy , Timmers Inge , Tunick Rachel , Wessel Ann , Wu Bai‐Lin , Levy Harvey , Elsas Louis , Berry Gerard T. 
Published: July 2011

AbstractBackgroundClassic galactosemia is an autosomal recessive disorder due to galactose‐1‐phosphate uridyltransferase (GALT) deficiency. Newborn screening and early treatment do not completely prevent tremor, speech deficits, and diminished IQ in both sexes and premature ovarian insufficiency (POI) in women. Data on how individuals with galactosemia fare as adults will improve our ability to predict disease progression.MethodsThirty‐three adults (mean age = 32.6 ± 11.7 years; range = 18–59) with classic galactosemia, confirmed by genotype and undetectable GALT enzyme activity, were evaluated. Analyses assessed associations among age, genotype, clinical features and laboratory measures.ResultsThe sample included 17 men and 16 women. Subjects exhibited cataracts (21%), low bone density (24%), tremor (46%), ataxia (15%), dysarthria (24%), and apraxia of speech (9%). Subjects reported depression (39%) and anxiety (67%). Mean full scale IQ was 88 ± 20, (range = 55–122). All subjects followed a dairy‐free diet and 75–80% reported low intake of calcium and vitamin D. Mean height, weight and body mass were within established norms. All female subjects had been diagnosed with POI. One woman and two men had had children. Logistic regression analyses revealed no associations between age, genotype or gender with IQ, tremor, ataxia, dysarthria, apraxia of speech or anxiety. Each 10‐ year increment of age was associated with a twofold increase in odds of depression.ConclusionsTaken together, these data do not support the hypothesis that galactosemia is a progressive neurodegenerative disease. However, greater attention to depression, anxiety, and social relationships may relieve the impact of this disorder in adults.
Lipid and Biomass Distribution and Recovery from Two Microalgae by Aqueous and Alcohol Processing
Authors: Wang Guang , Wang Tong 
Published: July 2011

AbstractThe objective of this study was to determine lipid and biomass distribution during aqueous and alcohol processing of oleaginous microalgae, with the intention of fully extracting lipid from the dewatered cell paste. Two species, Nannochloropsis and Schizochytrium, were used. It is shown that most of the total lipid, 73% for Nannochloropsis and 87% for Schizochytrium, was held by the cell solids obtained by centrifugation during the aqueous process, justifying the need to develop a more effective lipid‐extraction method. Use of ethanol at elevated temperature enabled efficient extraction of lipid from the cell mass and at the same time improved biomass precipitation and recovery in the solid or cake fraction. More than 68 and 95% of total lipid was recovered on a 50‐g scale (as‐is paste basis) from Nannochloropsis and Schizochytrium, respectively. Approximately 65% of the biomass was recovered in the solid fraction for both algae from the alcohol process, compared with the much lower biomass recovery, 38 and 16% for Nannochloropsis and Schizochytrium by the aqueous process. Therefore, oil and biomass fractionation by use of pure water is far less effective than fractionation by use of alcohol, and the alcohol process has great promise in algal oil recovery.
Numerical modelling of the hydrocarbon generation of Tertiary source rocks intruded by doleritic sills in the Zhanhua depression, Bohai Bay Basin, China
Authors: Wang Kai , Lu Xiancai , Chen Meng , Ma Yemu , Liu Kuiyuan , Liu Lianqi , Li Xiaozhao , Hu Wenxuan 
Published: July 2011

AbstractAn igneous hydrocarbon reservoir had been found in the Zhanhua depression, Bohai Bay Basin, eastern China. Two doleritic sills successively intruded into the immature source rock of the third member of the Shahejie Formation (Es3). The heat released from the magma changed the mineral composition of wall rocks and accelerated the maturity of organic matter. Thin hornfels and carbargilite zones were found next to the sills. The vitrinite reflectances (%Ro) of these heated wall rocks increased to at least 1.4% near the contacts (<50 m), and accumulation of oil was found in the hornfels zone and dolerite bodies. With the aim of understanding the influence of the sills on the hydrocarbon generation process, a complex heat conduction model was used to simulate the thermal history of the organic‐rich wall rocks, in which both the latent heat of crystallization of intrusions and vapourization heat of pore water in wall rocks were considered. The simulation results suggested that the cooling of each sill continued for about 0.1 Ma after its emplacement and the temperature of wall rocks was considerably raised. The peak temperature (Tpeak) that wall rocks experienced can reach 460–650°C in the region of 10 m away from the contacts. The thermal model was qualitatively verified by comparing the experimental data of vitrinite reflectances and mineral geothermometers of the wall rocks with the simulation results. Furthermore, we modelled the hydrocarbon generation of the source rocks based on the simulated thermal history. In the region of about 100 m from the contacts, the organic matter was heated and partially transformed into hydrocarbon within only a few 1000 years, which was significantly faster than the normal burial generation process.
Involving practice nurses in primary care research: the experience of multiple and competing demands
Authors: Boase Sue , Kim Youngsuk , Craven Anthea , Cohn Simon 
Published: July 2011

boase s., kim y., craven a. & cohn s. (2012) Involving practice nurses in primary care research: the experience of multiple and competing demands. Journal of Advanced Nursing68(3), 590–599.AbstractAim.  This paper is a report of a study of the experiences of practice nurses delivering a complex research intervention in an exploratory randomized controlled trial in primary care.Background.  As practice nurses increasingly become involved in primary care research, it is important to understand not only what impact this may have on their existing role but also equally on what their potential contribution might be.Method.  Fourteen of the 15 practice nurses involved in the delivery of a complex intervention were purposively sampled and interviewed in their workplace between June and October 2007. Interviews were audio‐recorded, transcribed and analysed using a Framework Approach and NVivo software.Findings.  Time influenced the nurses’ engagement with the various aspects of the trial and meant that they constantly had to make judgments and decisions in response to the multiple agendas presented to them: they had to negotiate a range of competing loyalties between their professional clinical role, their role in the research and practice teams and their relationship with patients. The nurses’ accounts consequently provide insight into the active role they played both in the trial process and the delivery of the complex intervention.Conclusion.  The nurses were key to the delivery of the trial. If practice nurses are to develop a research role in their professional work, it is important to understand their perceptions and the impact such involvement has on them and their practice. Consideration of these factors is consequently valuable when developing research in primary care settings.
Effects of a relaxation training programme on immediate and prolonged stress responses in women with preterm labour
Authors: Chuang Li‐Lan , Lin Li‐Chan , Cheng Po‐Jen , Chen Chung‐Hey , Wu Shiao‐Chi , Chang Chuan‐Lin 
Published: July 2011

chuang l.‐l., lin l.‐c., cheng p.‐j., chen c.‐h., wu s.‐c. & chang c.‐l. (2012) Effects of a relaxation training programme on immediate and prolonged stress responses in women with preterm labour.Journal of Advanced Nursing68(1), 170–180.AbstractAim. This paper is a report of an experimental study of the effects of relaxation‐training programme on immediate and prolonged stress responses in women with preterm labour.Background. Hospitalized pregnant women with preterm labour experience developmental and situational stress. However, few studies have been performed on stress management in such women.Methods. An experimental pretest and repeated post‐test design was used to compare the outcomes for two groups in northern Taiwan from December 2008, to May 2010. A total of 129 women were randomly assigned to an experimental (n = 68) or control (n = 61) group. The experimental group participants were instructed to listen daily to a 13‐minute relaxation programme. Measurements involved the stress visual analogue scale, finger temperatures, State Trait Anxiety Inventory, Perceived Stress Scale and Pregnancy‐related Anxiety. Two‐way analysis of variance and hierarchical linear modelling were used to analyse the group differences.Results. Compared with those in the control group, participants in the experimental group showed immediate improvements in the stress visual analogue scale scores and finger temperatures. The State Trait Anxiety Inventory‐State subscale score for the experimental group was significantly lower than that for the control group (P = 0·03). However, no statistically significant differences for the Perceived Stress Scale and Pregnancy‐related Anxiety scores were found between the experimental group and the control group.Conclusions. The relaxation‐training programme could improve the stress responses of women with preterm labour.