bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A Very Active Cu‐Catalytic System for the Synthesis of Aryl, Heteroaryl, and Vinyl Sulfides.
Authors: Kabir M. Shahjahan , Lorenz Michael , Van Linn Michael L. , Namjoshi Ojas A. , Ara Shamim , Cook James M. 
Published: September 2010

AbstractThe complex generated from CuI and cis‐1,2‐cyclohexanediol is highly efficient for the coupling of various thiols with vinyl, aryl, and heteroaryl iodides and bromides.
ChemInform Abstract: A Highly Efficient, Green, Rapid, and Chemoselective Oxidation of Sulfides Using Hydrogen Peroxide and Boric Acid as the Catalyst under Solvent‐Free Conditions.
Authors: Rostami Amin , Akradi Jamal 
Published: September 2010

AbstractSulfides possessing functional groups like alcohol, aldehyde and ester are selectively oxidized to sulfoxides or sulfones.
ChemInform Abstract: Synthesis of Substituted N‐Hydroxyureas via the in situ Generation of t‐Butoxy Isocyanate.
Authors: Krause Josef G. , Leskiw Brian D. , Emery Michelle L. , McGahan Megan E. , McCourt Mary P. , Priefer Ronny 
Published: September 2010

AbstractThe attempt to prepare hydrazine products starting from carbamate (I) and amines yields N‐substituted ureas instead.
ChemInform Abstract: Palladium‐Catalyzed Domino Process to Spirooxindoles: Ligand Effect on Aminopalladation versus Carbopalladation.
Authors: Jaegli Stephanie , Erb William , Retailleau Pascal , Vors Jean‐Pierre , Neuville Luc , Zhu Jieping 
Published: September 2010

AbstractA novel Pd‐catalyzed domino spirocyclization process is presented furnishing biologically relevant spiropyrrolidine‐3,3′‐oxindoles in moderate yields.
ChemInform Abstract: Zirconium(IV)‐ and Hafnium(IV)‐Catalyzed Highly Enantioselective Epoxidation of Homoallylic and Bishomoallylic Alcohols.
Authors: Li Zhi , Yamamoto Hisashi 
Published: September 2010

AbstractThe hafnium catalytic system bearing a chiral bishydroxamic acid ligand in general exhibits better results in terms of reactivity and enantioselectivity than the analogous zirconium catalyst.
ChemInform Abstract: Cyclodehydration of Fluorinated Diols Using the Mitsunobu Reaction: Highly Efficient Synthesis of Trifluoromethylated Cyclic Ethers.
Authors: Prakash G. K. Surya , Do Clement , Wang Fang , Mathew Thomas , Olah George A. 
Published: September 2010

AbstractThe title reaction of the diastereomerically pure diol (VII) affords the corresponding oxirane (VIII) with complete inversion of configuration.
ChemInform Abstract: Carbon—Carbon Bond Formation and Pyrrole Synthesis via the [3,3] Sigmatropic Rearrangement of O‐Vinyl Oxime Ethers.
Authors: Wang Heng‐Yen , Mueller Daniel S. , Sachwani Rachna M. , Londino Hannah N. , Anderson Laura L. 
Published: September 2010

AbstractThe isomerization of O‐allyl oximes to O‐vinyl oximes and the conversion of the latter to pyrroles are described.
ChemInform Abstract: Pd‐Catalyzed Carboamination of Oxazolidin‐2‐ones: A Stereoselective Route to trans‐2,5‐Disubstituted Pyrrolidines.
Authors: Lemen Georgia S. , Wolfe John P. 
Published: September 2010

AbstractTitle reaction of homoallyloxazolidinones, e.g. (I) and (IV), with aryl bromides provides access towards pyrrolidino‐fused oxazolidinones like (III) and (VI) in excellent diastereoselectivity.
ChemInform Abstract: Metal‐Free Coupling of Azoles with 2‐ and 3‐Haloindoles Providing Access to Novel 2‐ or 3‐(Azol‐1‐yl)indole Derivatives.
Authors: Poirier Martin , Goudreau Sebastien , Poulin Jason , Savoie Jolaine , Beaulieu Pierre L. 
Published: September 2010

AbstractA range of 2‐haloindole derivatives couples smoothly towards the nitrogen of various heterocycles.
ChemInform Abstract: Copper Oxide Nanoparticles Catalyzed Vinylation of Imidazoles with Vinyl Halides under Ligand‐Free Conditions.
Authors: Reddy V. Prakash , Kumar A. Vijay , Rao K. Rama 
Published: September 2010

AbstractThe recyclable catalyst can be used for the cross‐coupling of imidazoles with trans‐β‐halostyrenes under ligand‐free conditions.
ChemInform Abstract: Mild, Convenient and Versatile Cu‐Mediated Synthesis of N‐Aryl‐2‐imidazolidinones.
Authors: Stabile Paolo , Lamonica Alessandro , Ribecai Arianna , Castoldi Damiano , Guercio Giuseppe , Curcuruto Ornella 
Published: September 2010

AbstractOptimized conditions are developed for the mono N‐arylation of unprotected 2‐imidazolidinone.
ChemInform Abstract: Chiral Broensted Acid Catalyzed Enantioselective Addition of α‐Isocyanoacetamides to Aldehydes.
Authors: Zeng Xiaofei , Ye Kehan , Lu Min , Chua Pei Juan , Tan Bin , Zhong Guofu 
Published: September 2010

AbstractA highly enantioselective addition of α‐isocyanoacetamides (I) and (IV) towards aliphatic aldehydes (II) is presented, involving a chiral octahydro‐BINOL‐derived phosphoric acid bearing bulky groups at 3,3′‐position (SIBIPHOS) as catalyst.
ChemInform Abstract: Catalytic Asymmetric Protonation of Chiral Calcium Enolates via 1,4‐Addition of Malonates.
Authors: Poisson Thomas , Yamashita Yasuhiro , Kobayashi Shu 
Published: September 2010

AbstractThe reaction conditions are optimized with respect to malonate ester, calcium alkoxide, chiral ligand, type of alcohol additive and phenol, solvent, and reaction temperature.
ChemInform Abstract: Melamine Trisulfonic Acid as a New, Efficient and Reusable Catalyst for the Chemoselective Oxathioacetalization of Aldehydes.
Authors: Shirini F. , Albadi J. 
Published: September 2010

AbstractMelamine trisulfonic acid (MTSA) is found to be an efficient and reusable catalyst for the chemoselective oxathioacetalization of aldehydes.
ChemInform Abstract: An Efficient, One‐Pot, Regioselective Synthesis of 1,4‐Diaryl‐1H‐1,2,3‐triazoles Using Click Chemistry.
Authors: Kumar Dalip , Reddy Vaddula Buchi 
Published: September 2010

Abstract1,3‐Dipolar cycloaddition of aryl azides, generated in situ, with terminal alkynes affords the synthetically important triazole products in good yields.
ChemInform Abstract: Multicomponent, Solvent‐Free Synthesis of 12‐Aryl‐8,9,10,12‐tetrahydrobenzo[a]‐xanthen‐11‐one Derivatives Catalyzed by Cyanuric Chloride
Authors: Zhang Zhan‐Hui , Zhang Peng , Yang Shu‐Hong , Wang Hong‐Juan , Deng Jia 
Published: September 2010

Abstract22 examples
ChemInform Abstract: Ceric Ammonium Nitrate: An Efficient Catalyst for One‐Pot Synthesis of 2,2,4‐Trimethyl‐1,2‐dihydroquinolines
Authors: Durgadas Shylaprasad , Chatare Vijay K. , Mukkanti Khagga , Pal Sarbani 
Published: September 2010

Abstractfrom substituted anilines and acetone via a modified Skraup reaction
ChemInform Abstract: Highly Enantioselective Relay Catalysis in the Three‐Component Reaction for Direct Construction of Structurally Complex Heterocycles.
Authors: Wang Chao , Han Zhi‐Yong , Luo Hong‐Wen , Gong Liu‐Zhu 
Published: September 2010

AbstractThe three‐component cascade reaction, consisting of an enantioselective [4 + 2] cycloaddition reaction catalyzed by chiral phosphoric acid and a subsequent catalytic intramolecular hydroamination by gold(I) complex, provides a method to access structurally diverse julolidine derivatives.
ChemInform Abstract: Design and Synthesis of Benzosultine‐Sulfone as a o‐Xylylene Precursor via Cross‐Enyne Metathesis and Rongalite: Further Expansion to Polycyclics via Regioselective Diels—Alder Reaction.
Authors: Kotha Sambasivarao , Chavan Arjun S. 
Published: September 2010

AbstractHeating the benzosultine‐sulfone (XI) results in selective formation of a o‐xylylene intermediate which smoothly reacts with dienophiles to afford cycladducts of type (XIII) and (XIV).
ChemInform Abstract: Synthesis and Cyclooxygenase Inhibitory Activities of Some N‐Acylhydrazone Derivatives of Isoxazolo[4,5‐d]pyridazin‐4(5H)‐ones.
Authors: Uensal‐Tan Oya , Oezden Kevser , Rauk Arvi , Balkan Ayla 
Published: September 2010

AbstractThe title derivatives (III) bearing an N‐acylhydrazone moiety at the fifth position are prepared as potential COX‐2 inhibitors.
ChemInform Abstract: A Novel Biginelli‐Like Reaction: An Efficient One‐Pot Synthesis of Spiro[oxindole‐quinazoline/pyrimidine]ones
Authors: Kefayati Hassan , Rad‐Moghadam Kurosh , Zamani Masoumeh , Hosseyni Sanaz 
Published: September 2010

Abstractvia three‐component cyclocondensation of cyclic or acyclic dicarbonyl compounds, isatin derivatives, and urea derivatives
ChemInform Abstract: One‐Step Efficient Synthesis of Pyrazolo[3,4‐f]quinoline Derivatives under Microwave Irradiation.
Authors: Tu Shu‐Jiang , Wu Shan‐Shan , Zhang Xiao‐Hong , Han Zheng‐Guo , Cao Xu‐Dong , Hao Wen‐Juan 
Published: September 2010

AbstractAn efficient and inexpensive method with simple work‐up is used for the preparation of title compounds, e.g. (IV), which may be used for biomedical screening.
ChemInform Abstract: Staudinger and retro‐Staudinger Reactions. The Dichloro‐β‐lactam Moiety as a Useful Handle for the Synthesis of 4‐Aryl‐2H‐1,3‐benzothiazine 1,2‐Dioxides.
Authors: Fodor Lajos , Csomos Peter , Csampai Antal , Sohar Pal 
Published: September 2010

AbstractThe title compounds (V), which cannot be obtained by direct oxidation of (I), are prepared using the reversible formation of a dichloro‐β‐lactam moiety as novel protecting group.
ChemInform Abstract: Synthesis and in vitro Evaluation of New Tacrine Derivatives‐bis‐alkylene Linked 7‐MEOTA.
Authors: Korabecny Jan , Holas Ondrej , Musilek Kamil , Pohanka Miroslav , Opletalova Veronika , Dohnal Vlastimil , Kuca Kamil 
Published: September 2010

AbstractThe novel tacrine derivatives (III) exhibit lower anticholinesterase activity compared to THA.
ChemInform Abstract: Identification of Very Potent Inhibitor of Human Aminopeptidase N (CD13).
Authors: Grzywa Renata , Oleksyszyn Jozef , Salvesen Guy S. , Drag Marcin 
Published: September 2010

AbstractBroad SAR studies of two classes of phosphinate inhibitors result in the identification of compound (I) as a very potent inhibitor of human aminopeptidase N.
ChemInform Abstract: Enantiospecific, Biosynthetically Inspired Formal Total Synthesis of (+)‐Liphagal (VII).
Authors: George Jonathan H. , Baldwin Jack E. , Adlington Robert M. 
Published: September 2010

AbstractKey feature of the title synthesis is a ring expansion of a fused 6,6‐ring system via stereoselective epoxide ring opening and combined recyclization—furan ring closure to build the tetracyclic framework (VI).
ChemInform Abstract: Methanolysis of 3β‐Substituted 4,5‐Epoxyandrostanes Catalyzed by Tetracyanoethylene.
Authors: Uyanik Cavit , Malay Aslihan , Sonmez Hayal B. , Queudrue Loic , Hanson James R. 
Published: September 2010

AbstractThe presence of a 3β‐acetoxyl or 3β‐hydroxyl group in the title compounds modifies the structure of the products arising from the methanolysis.
ChemInform Abstract: Protecting Group Effect on the 1,2‐Dihydrogenation of 19‐Hydroxysteroids: A Highly Efficient Protocol for the Synthesis of Estrogens.
Authors: Jing Yu , Xu Cheng‐Gong , Ding Kai , Lin Jing‐Rong , Jin Rong‐Hua , Tian Wei‐Sheng 
Published: September 2010

AbstractThe 1,2‐dehydrogenation of 19‐oxandrost‐4‐ene‐3,17‐dione (I) with DDQ in refluxing dioxane is found to be remarkably dependent on the O‐protecting group.
ChemInform Abstract: Three‐Component Reaction of a δ‐Hydroxy‐α,β‐unsaturated Aldehyde with Arylamines and 1,3‐Diketones: A Novel Synthesis of Oxa‐Aza Bicycles.
Authors: Reddy Basi V. Subba , Divyavani Ch. , Begum Zubeda , Yadav Jhillu S. 
Published: September 2010

AbstractPerlin aldehyde (I) reacts with β‐enamino ketones or esters, generated in situ, to produce the desired heterobicycles (IV) with high selectivity.
ChemInform Abstract: Homoisoflavonoid Derivatives from the Roots of Ophiopogon japonicus and Their in vitro Antiinflammation Activity
Authors: Hung Tran Manh , Cao Van Thu , Nguyen Tien Dat , Ryoo Sung‐Woo , Lee Jeong Hyung , Kim Jin Cheol , Na Minkyun , Jung Hyun‐Ju , Bae KiHwan , Min Byung Sun 
Published: September 2010

Abstractisolation, structure elucidation and antiinflammatory activities of ophiopogonanone G (I), ophiopogoside A (IIa), and ophiopogoside B (IIb)
ChemInform Abstract: Antimicrobial Selaginellin Derivatives from Selaginella pulvinata.
Authors: Cao Yuan , Chen Ji‐Jun , Tan Ning‐Hua , Oberer Lukas , Wagner Trixie , Wu Yong‐Ping , Zeng Guang‐Zhi , Yan He , Wang Qiang 
Published: September 2010

AbstractIsolation, structure elucidation and antimicrobial activities of three new selaginellin derivatives, i.e.
ChemInform Abstract: Cell Cycle Disruption and Apoptotic Activity of 3‐Aminothiazolo[3,2‐a]benzimidazole‐2‐carbonitrile and Its Homologues.
Authors: Sarhan Abdelwareth A. O. , Al‐Dhfyan Abdullah , Al‐Mozaini Maha A. , Adra Chaker N. , Aboul‐Fadl Tarek 
Published: September 2010

AbstractEvaluation of title compounds for their in vitro antiproliferative properties reveals significant potency only in the case of derivative (I).
ChemInform Abstract: Cyclic Tri‐ and Pentavalent Amidoesters and Diamides with a Stereogenic Phosphorus Atom in Asymmetric Synthesis. Part 1. Stoichiometric Reagents
Authors: Drabowicz Jozef , Krasowska Dorota , Lopusinski Andrzej , Heugebaert Thomas S. A. , Stevens Christian V. 
Published: September 2010

AbstractReview: 77 refs.
ChemInform Abstract: Catalytic Chemistry of Supported Heteropolyacids and Their Applications as Solid Acids to Industrial Processes
Authors: Kamiya Yuichi , Okuhara Toshio , Misono Makoto , Miyaji Atsuyuki , Tsuji Katsuyuki , Nakajo Tetsuo 
Published: September 2010

AbstractReview: 73 refs.
ChemInform Abstract: Advancement of Synchrotron Radiation Protein Crystallography Aimed by the Targeted Protein Research Program: Beamline Developments at the Photon Factory
Authors: Wakatsuki Soichi , Yamada Yusuke , Chavas Leonard M. G. , Igarashi Noriyuki , Kawasaki Masato , Kato Ryuichi , Hiraki Masahiko , Matsugaki Naohiro 
Published: September 2010

AbstractReview: 10 refs.
Identification and control of a riser‐type FCC unit
Authors: Alaradi Abdul‐Alghasim , Rohani Sohrab 
Published: September 2010

AbstractThis paper addresses the use of feedforward neural networks for the steady‐state and dynamic identification and control of a riser type fluid catalytic cracking unit (FCCU). The results are compared with a conventional PI controller and a model predictive control (MPC) using a state space subspace identification algorithm. A back propagation algorithm with momentum term and adaptive learning rate is used for training the identification networks. The back propagation algorithm is also used for the neuro‐control of the process. It is shown that for a noise‐free system the adaptive neuro‐controller and the MPC are capable of maintaining the riser temperature, the pressure difference between the reactor vessel and the regenerator, and the catalyst bed level in the reactor vessel, in the presence of set‐point and disturbance changes. The MPC performs better than the neuro controller that in turn is superior to the conventional multi‐loop diagonal PI controller.
Décontamination à l'échelle pilote de sédiments pollués en métaux toxiques par lixiviation chimique et biologique
Authors: Blais Jean‐François , Mercier Guy , Chartier Myriam 
Published: September 2010

AbstractDes travaux pilotes ont été menés dans le cadre de cette recherche afin de tester différents scénarios de décontamination de sédiments pollués par plusieurs métaux lourds (Cd, Cr, Cu, Ni, Pb et Zn). Des essais de lixiviation chimique et biologique ont été réalisés en réacteur de 350 L. L'application de lavages acides (pH 2.0–3.0) des sédiments constitue une approche peu efficace pour l'enlèvement des métaux toxiques. L'ajout d'un agent oxydant lors du premier lavage augmente considérablement les rendements d'enlèvement du Pb (53–76 %), Cd (54–92 %) et Zn (69–93 %). Les autres métaux demeurent toutefois difficiles à extraire: Cr (13–30 %), Cu (11–34 %) et Ni (0–16 %). La biolixiviation seule ou en combinaison avec un ou deux lavages chimiques, représente une approche efficace pour l'élimination du Cd (82–100 %), Cu (44–70 %) et Zn (80–87 %). Par contre, cette technique présente peu d'intére̊t pour la réduction des teneurs en Cr (6–16 %), Ni (12–34 %) et Pb (14–33 %). Les métaux solubilisés par lixiviation chimique et/ou biologique peuvent être précipités efficacement lors de la neutralisation des effluents acides par une solution de chaux.
Effect of Combustion Improver on Combustion Behavior of Cigarette Paper by Simultaneous TG/DSC Detection
Authors: Li Huirong , Liu Yi , Li Dan , Cai Bin , Chen Yikun , Cheng Zhangang 
Published: September 2010

AbstractCombustion behavior of cigarette paper containing different content of combustion improver was investigated in order to provide direct experiment data to elucidate lower components in cigarette smoke caused by combustion improver in cigarette paper. The content of the combustion improver was denoted as "organic" potassium index and determined by atomic absorption spectroscopy and ionic spectroscopy. The combustion process obtained by simultaneous thermal analysis was divided into four stages: weight loss due to loss of absorbent water, decomposition of the cellulose, the oxidation of the cellulose char and decomposition of calcium carbonate. Combustion improver reduced the temperature of cellulose decomposition 3–12 K and contributed to oxidation of the cellulose char. Ignition point was gained and reduced 3–8 K by combustion improver. Above results were further verified by samples from two other cigarette paper factories. Mechanism of lower components in cigarette smoke by the combustion improver in cigarette paper was discussed.
Synthesis, Crystal Structure, Luminescence and Thermal Stability of a New Coordination Polymer Constructed by Europium(III) and 2,4‐Dichlorophenoxyacetate
Authors: Yang Yingqun , Li Changhong , Li Wei , Yi Zhengji 
Published: September 2010

AbstractA new coordination polymer {[Eu2(Cl2C6H3OCH2COO)6(H2O)4]·(DMF)4·(H2O)2}nwith 2,4‐dichlorophenoxy acetic acid as the ligand has been synthesized. The crystal data for this complex are as follows: monoclinic, space groupP2(1)/n,a=0.86474(17) nm,b=3.2475(7) nm,c=1.3843(3) nm,β=92.81(3) °,V=3.8827(13) nm3,Dc=1.718 g/cm3,Z=2,µ(Mo Kα)=2.093 mm−1,F(000) =2008, final discrepancy factorsR1=0.0454,wR2=0.1165. The crystal structure shows that the title complex forms one‐dimensional chain structure by bridging 2,4‐dichlorophenoxy acetic acid anions. Every centric europium(III) ion is coordinated with ten oxygen atoms from five 2,4‐dichlorophenoxy acetic acid anions and two water molecules, giving a ten‐coordinated distorted bicapped square antiprism geometry. The luminescent property and thermal stability of the complex are also studied.
Synthesis and Reactions of Halo‐, Arylazo‐substituted 3‐(3‐(1‐naphthyl)acryloyl)tropolones. Formation of (Naphthalen‐1‐yl)vinyl)substituted Heterocycle‐fused Troponoid Compounds
Authors: Gao Wentao , Sun Mingchun , Li Yang 
Published: September 2010

AbstractThe starting substrate 3‐(3‐(1‐naphthyl)acryloyl)tropolone (3) was achieved by the aldol condensation reaction of 3‐acetyltropolone with 1‐naphthaldehyde. Compound 3 reacted with bromine to afford 7‐bromo‐3‐ (3‐(1‐naphthyl)acryloyl)tropolone (4), 5,7‐dibromo‐3‐(3‐(1‐naphthyl)acryloyl)tropolone (5) according to the molar ratio of the reactants. Iodination of 3 gave 7‐iodo‐3‐(3‐(1‐naphthyl)acryloyl)tropolone (6). Azo‐coupling reactions of 3 gave the 5‐arylazo‐3‐(3‐(1‐naphthyl)acryloyl)tropolones (7–8). Compounds 3, 4, 6 reacted respectively with hydroxyamine to give the corresponding 3‐[2‐(1‐naphthyl)vinyl]‐8H‐cyclohepta[d]isoxazol‐8‐ones (9–11). The reactions of 3, 5 with phenylhydrazine and substituted phenylhydrazines gave 3‐[2‐(1‐naphthyl)vinyl]‐1‐phenylcyclohepta[c]pyrazol‐8(1H)‐ones (12–18).
Synthesis, Characterization and Anti‐inflammatory Activity of 5‐{[((5‐Substituted‐aryl)‐1,3,4‐thiadiazol‐2‐yl)thio]‐n‐alkyl}‐1,3,4‐oxadiazole‐2‐thiol
Authors: Shirote Pramodkumar Jaykumar , Bhatia Manish Sudesh 
Published: September 2010

AbstractA series of potent and less toxic, 5‐{[((5‐substituted aryl)‐1,3,4‐thiadiazol‐2‐yl) thio]‐n‐alkyl}‐1,3,4‐oxadiazole‐2‐thiol was synthesized. Each compound was evaluated for anti‐inflammatory activity by carrageenan‐induced rat paw oedema method. Compounds PS1, PS4, PS9, and PS12 showed comparatively potent anti‐inflammatory activity as compared to control as well as other test compounds. These potent compounds were also tested for acute ulcerogenic activity. Results of both studies were found statistically significant.
One‐pot Synthesis of 2,4‐Diamino‐substituted Thieno[3,2‐d]pyrimidines
Authors: Li Xiaoying , Zhang Yangming , Tang Jie , Yang Fan , Nan Fajun 
Published: September 2010

AbstractAn efficient one‐pot synthetic approach to 2,4‐diamino‐substituted thieno[3,2‐d]pyrimidines from 2,4‐dichlorothieno[3,2‐d]pyrimidine was described.
Solid Phase Extraction of Uranium by Naphthalene‐Methyltrioctylammonium Chloride and Arsenazo(III) Adsorbent and Subsequent Spectrophotometric Determination
Authors: Behpour M. , Ghoreishi S. M. , Nikkhah Qamsari Z. , Samiei M. , Soltani N. 
Published: September 2010

AbstractA simple and effective method has been presented for the preconcentration of uranium by solid phase extraction. For this purpose arsenazo(III) supported on naphthalene‐methyltrioctylammonium chloride was used as an adsorbent and uranium solution at pH 3.5 with flow rate of 1 mL·min−1 was passed through the column. Therefore, uranium‐arsenazo(III) complex was formed onto column. Uranium was quantitatively eluted with 5 mL of a 0.1% ammonium tetraphenylborate and determined by spectrophotometric method at 652 nm. Several parameters such as pH, amount of reagents, sample volume, etc. were investigated. The effect of diverse ions on the preconcentration has also been studied and the optimized conditions developed have been utilized for the trace determination of uranium. A preconcentration factor of 100 was achieved. The relative standard deviation (N=8) was 0.5% for 3 ng· mL−1 of uranium. The three sigma detection limit (36) was 0.045 ng·mL−1
A 4‐Methylumbelliferone‐based Fluorescent Probe for Sodium New Houttuyfonate
Authors: Yang Xiaofeng , Wang Liping , Zhao Minglei , Qi Haiping , Wu Yao 
Published: September 2010

AbstractA new fluorogenic probe for sodium new houttuyfonate (SNH) was proposed. 4‐Methylumbelliferyl‐2,4‐dinitrobenzenesulfonate (4‐MUDNBS) was a nonfluorescent compound and was synthesized via the one‐step reaction of 4‐methylumbelliferone (4‐MU) with 2,4‐dinitrobenzenesulfonyl chloride. In basic media, SNH was decomposed to produce sodium sulfite, which then reacted with 4‐MUDNBS to yield highly fluorescent 4‐MU, hence leading to the fluorescence increase of the reaction solution. A linear correlation existed between the emission intensity and the concentration of SNH within the range from 0.5 to 15 μg·mL−1 with a detection limit of 0.15 μg· mL−1 (3δ). The effect of substituents on the benzenesulfonyl moiety of the probe is discussed, and the presence of electronegative groups is favorable for the proposed cleavage reaction.