bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pharmacy faculty experiences with student academic entitlement: a multinational study from the Arab world
Authors: Hammoudi Halat Dalal , Alsous Mervat M. , Al-Jumaili Ali Azeez , Malki Ahmed , Ahmed Kawther Khalid , Hamad Anas , Darwish Rula , Thomas Dixon , Bukhatwa Salma , Khdour Maher , Alkhudair Nora , Al Balushi Abdullah Ali , Khalifa Sherif , Alsharif Naser Z. , Rahal Mohamad 
Published: April 2024

AbstractAcademic Entitlement (AE) is the expectation by students to receive high grades or preferential treatment without significant effort. Exploring AE from faculty perspective has not been investigated in Arab colleges of pharmacy. The aim of this study was to explore experiences and perceptions towards student AE among pharmacy faculty in the Arab World. A cross-sectional, self-administered, anonymous, electronic survey was sent to pharmacy faculty across pharmacy colleges in Arab countries. The survey collected demographic data, an AE measure including 17 items reflecting seven AE components, and faculty perceptions and perceived reasons for AE. A total of 345 responses were collected. The AE level was moderate (46.05 ±7.29), and the highest scores among its components were for customer service expectation (62%) and responsibility avoidance (59%). In multiple linear regression, AE showed positive significant association with faculty in clinical pharmacy departments and those having fewer years of experience. Most common complaints heard by faculty from students were requests to turn in assignments late (90%), while the most common communication issues faculty faced with students were unprofessional verbal communication (58%) and unprofessional messages on social media (57%). Poor admission criteria (40%) and existence of multiple private colleges of pharmacy (37%) were the most common perceived reasons for AE by participating faculty. This study reveals moderate AE experienced by pharmacy faculty in the Arab World, as well as common complaints, communication issues, and AE reasons. In collaboration with other stakeholders, faculty play an important role in indicating expectations from students regarding AE, and research is warranted to check if such interventions reduce AE among pharmacy students.
Increasing nurses’ occupational well-being: the role of career shocks, job crafting and supervisor autonomy support
Authors: Zhang Ying , Bu Xing , Zhang Na 
Published: April 2024

Abstract
Background
This study aims to explore the influence of career shocks on nurses’ occupational well-being through job crafting and the moderating role of supervisor autonomy support.

Method
The present study used a cross-sectional design. And the study included 714 frontline nurses in China, and we used structural equation modelling (SEM) to test our hypotheses.

Results
Job crafting mediated both the relationship between positive career shocks and occupational well-being and the relationship between negative career shocks and occupational well-being. Supervisor autonomy support moderated the indirect relationships.

Conclusions
Positive and negative career shocks could increase and impair nurses’ occupational well-being through job crafting, respectively. We contribute to helping nurses make sense of career shocks and preparing for career shocks, and hospital administrators and nurses’ direct supervisors can help nurse better cope with career shocks in attending job crafting activities and providing more autonomy supports.
Efficacy and safety of direct oral anticoagulants in patients with atrial fibrillation combined with chronic kidney disease: a systematic review and meta-analysis
Authors: Li Yaodi , Wu Shuyi , Zhou Jintuo , Zhang Jinhua 
Published: April 2024

Abstract
Background
Currently published studies have not observed consistent results on the efficacy and safety of direct oral anticoagulants (DOACs) use in patients with chronic kidney disease (CKD) combined with atrial fibrillation (AF). Therefore, this study conducted a meta-analysis of the efficacy and safety of DOACs for patients with AF complicated with CKD.

Methods
Database literature was searched up to May 30, 2023, to include randomized controlled trials (RCT) involving patients with AF complicated with CKD DOACs and vitamin K antagonists (VKAs). Stroke, systemic embolism (SE), and all-cause mortality were used as effectiveness indicators, and major bleeding, intracranial hemorrhage (ICH), fatal bleeding, gastrointestinal bleeding (GIB), and clinically relevant non-major bleeding (CRNMB) were used as safety outcomes.

Results
Nine RCT studies were included for analysis according to the inclusion criteria. Results of the efficacy analysis showed that compared with VKAs, DOACs reduced the incidence of stroke/SE (OR = 0.75, 95% CI 0.67–0.84) and all-cause deaths (OR = 0.84, 95% CI 0.75–0.93) in patients with AF who had comorbid CKD. Safety analyses showed that compared with VKAs, DOACs improved safety by reducing the risk of major bleeding (OR = 0.76, 95%CI 0.65–0.90), ICH (OR = 0.46, 95%CI 0.38–0.56), and fatal bleeding (OR = 0.75, 95%CI 0.65–0.87), but did not reduce the incidence of GIB and CRNMB.

Conclusion
Compared with VKAs, DOACs may increase efficacy and improve safety in AF patients with CKD (90 ml/min> Crcl≥15 ml/min), and shows at least similar efficacy and safety in AF patients with Kidney failure (Crcl<15 ml/min).
Fast, parallel, and cache-friendly suffix array construction
Authors: Khan Jamshed , Rubel Tobias , Molloy Erin , Dhulipala Laxman , Patro Rob 
Published: April 2024

AbstractPurposeString indexes such as the suffix array (sa) and the closely related longest common prefix (lcp) array are fundamental objects in bioinformatics and have a wide variety of applications. Despite their importance in practice, few scalable parallel algorithms for constructing these are known, and the existing algorithms can be highly non-trivial to implement and parallelize.MethodsIn this paper we presentcaps-sa, a simple and scalable parallel algorithm for constructing these string indexes inspired by samplesort and utilizing an LCP-informed mergesort. Due to its design,caps-sahas excellent memory-locality and thus incurs fewer cache misses and achieves strong performance on modern multicore systems with deep cache hierarchies.ResultsWe show that despite its simple design,caps-saoutperforms existing state-of-the-art parallelsaandlcp-array construction algorithms on modern hardware. Finally, motivated by applications in modern aligners where the query strings have bounded lengths, we introduce the notion of a bounded-contextsaand show thatcaps-sacan easily be extended to exploit this structure to obtain further speedups. We make our code publicly available athttps://github.com/jamshed/CaPS-SA.
Unveiling the impact of cryptic plasmids curing on Escherichia coli Nissle 1917: massive increase in Ag43c expression
Authors: Lin Qi , Jiang Zhuo , Zhong Bo , Chen Jian-qing , Lv Zheng-bing , Nie Zuo-ming 
Published: April 2024

AbstractEscherichia coli Nissle 1917 (EcN) is an important chassis strain widely used for the development of live biotherapeutic products (LBPs). EcN strain naturally harbors two cryptic plasmids with unknown function. During the development of LBPs using EcN strain, the cryptic plasmids were cured usually to avoid plasmid incompatibility or alleviate metabolic burdens associated with these cryptic plasmids. While the cryptic plasmids curing in EcN may appear to be a routine procedure, the comprehensive impact of cryptic plasmids curing on the EcN strain remains incompletely understood. In the present study, the effects of cryptic plasmids curing on EcN were investigated using transcriptome sequencing. The results revealed that only a small number of genes showed significant changes in mRNA levels after cryptic plasmid curing (4 upregulated and 6 downregulated genes), primarily involved in amino acid metabolism. Furthermore, the flu gene showed the most significant different expression, encoding Antigen 43 (Ag43) protein, a Cah family adhesin. Mass spectrometry analysis further confirmed the significant increase in Ag43 expression. Ag43 is commonly present in Escherichia coli and mediates the bacterial autoaggregation. However, despite the upregulation of Ag43 expression, no Ag43-mediated cell self-sedimentation was observed in the cured EcN strain. These findings contribute to making informed decisions regarding the curing of the cryptic plasmids when Escherichia coli Nissle 1917 is used as the chassis strain.
Profitability trend prediction in crypto financial markets using Fibonacci technical indicator and hybrid CNN model
Authors: Khattak Bilal Hassan Ahmed , Shafi Imran , Rashid Chaudhary Hamza , Safran Mejdl , Alfarhood Sultan , Ashraf Imran 
Published: April 2024

AbstractCryptocurrency has become a popular trading asset due to its security, anonymity, and decentralization. However, predicting the direction of the financial market can be challenging, leading to difficult financial decisions and potential losses. The purpose of this study is to gain insights into the impact of Fibonacci technical indicator (TI) and multi-class classification based on trend direction and price-strength (trend-strength) to improve the performance and profitability of artificial intelligence (AI) models, particularly hybrid convolutional neural network (CNN) incorporating long short-term memory (LSTM), and to modify it to reduce its complexity. The main contribution of this paper lies in its introduction of Fibonacci TI, demonstrating its impact on financial prediction, and incorporation of a multi-classification technique focusing on trend strength, thereby enhancing the depth and accuracy of predictions. Lastly, profitability analysis sheds light on the tangible benefits of utilizing Fibonacci and multi-classification. The research methodology employed to carry out profitability analysis is based on a hybrid investment strategy—direction and strength by employing a six-stage predictive system: data collection, preprocessing, sampling, training and prediction, investment simulation, and evaluation. Empirical findings show that the Fibonacci TI has improved its performance (44% configurations) and profitability (68% configurations) of AI models. Hybrid CNNs showed most performance improvements particularly the C-LSTM model for trend (binary-0.0023) and trend-strength (4 class-0.0020) and 6 class-0.0099). Hybrid CNNs showed improved profitability, particularly in CLSTM, and performance in CLSTM mod. Trend-strength prediction showed max improvements in long strategy ROI (6.89%) and average ROIs for long-short strategy. Regarding the choice between hybrid CNNs, the C-LSTM mod is a viable option for trend-strength prediction at 4-class and 6-class due to better performance and profitability.
Geomagnetic field variations due to solar tides at the Indian Observatories
Authors: Dwivedi Divyanshu , Chandrasekhar N. Phani 
Published: April 2024

AbstractThis study investigates the response of solar (S) tidal signatures on the horizontal component of the geomagnetic field at two observatories in India during 1980–2002 over solar cycles (SC) 21–23: Hyderabad (HYB), located in the low-latitude region, and Ettaiyapuram (ETT), situated at the magnetic equator. HYB represents the characteristics of solar quiet (Sq), while ETT is under the equatorial electrojet (EEJ) effect. Our results show the additional information about ter (S3), and quarta-diurnal (S4) tidal signatures of Sq and EEJ, along with diurnal (S1) and semi-diurnal (S2) at both observatories. In Sq solar tide, the average amplitude of S1 tide is consistently higher than that of EEJ tide by ~ 10%. During the same period, the S2, S3, and S4 tidal signatures of Sq are weaker than EEJ by ~ 2%, 5%, and 2.5%, respectively. During solar cycle maxima, the amplitude of the Sq tide is higher in SC-21 than in SC-22 and SC-23 by ~ 13% and 16%, while SC-22 has higher EEJ tidal amplitudes than other SCs by ~ 9%. We observe that the tidal signatures of Sq and EEJ closely follow the trend of solar radio flux ($$\sqrt{F10.7}$$

F
10.7

), except for S4 of Sq. The Pearson correlation coefficients (P) between $$\sqrt{F10.7}$$

F
10.7

and Sq/EEJ tidal amplitudes exhibit negative to positive correlation coefficients during different phases of SCs. The solar tidal amplitudes of Sq/EEJ (S1-S4) with $$\sqrt{F10.7}$$

F
10.7

during D, E, and J seasons have varying correlation coefficients, indicating that each tide has a distinct response on the geomagnetic field.
Graphical Abstract
Relationship between strength development and pozzolanic reactions in lime stabilized kaolinite
Authors: Ahmadullah Tasneem , Chrysochoou Maria 
Published: April 2024

AbstractThis study contributes to the quantitative understanding of kaolinite reactions with lime over two years. Unconfined Compressive Strength (UCS) increased linearly with time, doubling within one year, followed by a 14% decrease. Spectroscopic analysis of the system was performed at ten curing times (0, 7, 28, 90, 120, 180, 270, 360, 540 and 720 days) using Thermogravimetric Analysis (TGA), X-Ray Diffraction (XRD) and 2Nuclear Magnetic Resonance (NMR). Both TGA and XRD showed decrease of portlandite up to 180 days; complete consumption appears to have occurred by 270 days. TGA curves indicated an increase in hydration products in the first 360 days which followed a linear trend with UCS increase. No hydration products were observable by either XRD or NMR during that timeframe and no detectable changes in the kaolinite content either. After 360 days, growth in the hydrates in TGA slowed, and XRD, NMR showed a rapid increase of stratlingite (Ca2Al2SiO7∙8H2O) up to 720 days along with a decrease in the kaolinite signal. Collectively, these results point to two phases in kaolinite dissolution: the first phase, up to about 360 days, is incongruent, characterized by preferential release of Si or Al and portlandite consumption, leading to amorphous Calcium Silicate Hydrate (CSH) or an Afm phase, calcium monosulphoaluminate hydrate (CAH) formation. The second phase involves congruent dissolution and formation of Calcium Alumino Silicate Hydrate (CASH). It is hypothesized that CSH or CAH to CASH transformation occurs in the second stage, causing a disturbance in the cementitious matrix and loss in strength.
A case of Kommerell diverticulum in adolescence presented with dysphagia
Authors: Shinjo Hiroharu , Satokawa Hirono , Wakamatsu Hiroki , Yokoyama Hitoshi 
Published: April 2024

Abstract
Background
Kommerell diverticulum (KD) with right aortic arch and aberrant left subclavian artery (ALSCA) is a rare congenital aortic anomaly. To improve organ compression symptoms and avoid rupture of aneurysms in adulthood (19 years old–), surgical treatment is considered the only curative option. However, in childhood (–18 years old), several problems regarding approach and technique selection have been reported. Surgical treatment for KD in infancy (birth–2 years old) has been reported recently, but rarely in adolescence (13–19 years old). We herein report a case of KD in which the patient underwent graft replacement during adolescence.

Case presentation
A 13-year-old boy was admitted to our hospital presenting with dysphagia and body weight loss. Esophagography showed upper esophageal stenosis caused by extrinsic compression. Contrast-enhanced computer tomography showed saccular aneurysm formation of KD with right aortic arch (RAA) and ALSCA. Elective surgery including KD resection and graft replacement of the descending aorta was performed via right thoracotomy under partial extracorporeal circulation. The ALSCA was reconstructed by graft interposition. No postoperative complication was observed. Follow-up esophagography showed no residual stenosis.

Conclusion
We experienced a case of KD with dysphagia and weight loss in adolescence, which was successfully treated with surgery. Graft replacement could be an effective treatment option, facilitating recovery even during the growth period.
Influence of temperature on embryonic development of Pontastacus leptodactylus freshwater crayfish, and characterization of growth and osmoregulation related genes
Authors: Alvanou Maria V. , Feidantsis Konstantinos , Lattos Athanasios , Stoforiadi Anthi , Apostolidis Apostolos P. , Michaelidis Basile , Giantsis Ioannis A. 
Published: April 2024

AbstractNarrow clawed crayfish, Pontastacus (Astacus) leptodactylus, represents an ecologically and economically valuable freshwater species. Despite the high importance of artificial breeding for conservation purpose and aquaculture potential, hatching protocols have not been developed so far in this species. Further, limited knowledge exists regarding the artificial egg incubation, the temperature effect on embryonic development, hatching synchronization and hatching rate. In the present study we investigated the temperature increase (from 17 oC to 22oC) effects in two different embryonic developmental stages of P. leptodactylus. Furthermore, two primer pairs for the Fibroblast Growth Factor Receptor 4 (FGFR4) gene cDNA amplification were successfully designed, characterising for the first time the FGFR4 gene in P. leptodactylus in relation to different developmental stages and temperatures. Apart from the FGFR4 gene, the Na+/K+-ATPase α-subunit expression was also explored. Both the FGFR4 and Na+/K+-ATPase α-subunit expression levels were higher in embryos closer to hatching. Egg incubation at 22oC for seven days led to significant increase of FGFR4 expression in embryos from earlier developmental stages. Nevertheless, temperature increase did not affect FGFR4 expression in eggs from latter developmental stages and Na+/K+-ATPase α-subunit expression in all developmental stages. Temperature increase represents therefore probably a promising strategy for accelerating hatching in freshwater crayfish particularly in early developmental stages. Specifically, our results indicate that FGFR4 expression increased in embryonic stages closer to hatching and that temperature influences significantly its expression in embryos from earlier developmental stages. Overall, these findings can provide a better understanding of artificial egg incubation of P. leptodactylus, and therefore can be employed for the effective management of this species, both for economic and biodiversity retention reasons.
Birds and environment: a multidisciplinary approach to ecological, behavioural and conservation issues
Authors: Arya Ashish Kumar , Bachheti Archana , Sethi Vinaya Kumar , Joshi Kamal Kant 
Published: April 2024

AbstractBirds perform significant ecosystem services in the environment. Nevertheless, they have been facing threats to their survival globally. This special collection assembles diverse articles on various aspects of birds’ life, their interactions with the environment, their adaptations, and threats they have been facing along with conservation measures.
Autonomous inland navigation: a literature review and extracontractual liability issues
Authors: Domenighini Camilla 
Published: April 2024

AbstractPilot tests for (semi-)autonomous transport via inland waterways are already taking place in Belgium and other European countries. However, the full commercial implementation of autonomous inland shipping might be hampered by liability issues. The allocation of liability, especially extracontractual liability, is an important concern for shipowners who want to invest in autonomous barges, and for other ecosystem actors. For this reason, a balanced risk distribution framework could boost the investment decision. A legal analysis of the current laws and regulations is necessary to evaluate whether they can be applied to new autonomous systems. The research approach consists of two steps. First, an in-depth literature review is carried out to determine whether extracontractual liability research has already been conducted and to highlight the gaps in autonomous inland waterways transport studies. Once it is proved that the vast majority of the research focuses on technology, it can be affirmed that there is a need to inquire about extracontractual liability. In the second part, thus, the two international Conventions on liability limitation and collision in inland navigation are examined.
Evolution of therapeutic management of patients with ANCA associated vasculitis in France after licensing Rituximab use
Authors: Durel Cécile-Audrey , Thervet Eric Simon , Chauveau Dominique , Schmidt Aurélie , Terrier Benjamin , Bataille Pierre M 
Published: April 2024

Abstract
Introduction
In 2013, rituximab was approved in France for the treatment of ANCA-associated vasculitis (AAV). The aim of the study was to compare the treatment and health events of adult incident patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), included before rituximab approval (over 2010–2012, Group 1) and those included after rituximab approval (over 2014–2017, Group 2).

Method
Data were extracted from the French National Health Insurance database (SNDS) including outpatient health care consumption and hospital discharge forms. Comparisons between inclusion periods were performed using Wilcoxon and χ² tests. Kaplan-Meier method was used to model the duration of treatment induction, maintenance, and off-drug periods. Fine and Gray tests were used to compare treatment phase durations.

Results
A total of 694 GPA and 283 MPA patients were included in Group 1, while 668 GPA and 463 MPA patients were included in Group 2. Between the two inclusion periods, the proportions of patients treated with rituximab increased in the induction and maintenance phases whereas treatment with azathioprine declined. These proportions remained stable in the case of methotrexate, cyclophosphamide, and glucocorticoid-treated patients. Frequency of first-time hospitalized infections, diabetes and renal failure during the first year after inclusion increased for both groups.

Limitations of the study
This is a retrospective study based on claims data including only 76% of people covered by health insurance in France. The period studied includes the learning phase of using rituximab. This study lacks biological data and precise quantitative analysis for the use of steroids, therefore the criteria for establishing diagnosis and therapeutic choice were unknown.

Conclusions
Introduction of rituximab reduced the use of azathioprine without affecting the use of glucocorticoids or cyclophosphamide.