bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Design, Synthesis, and Antiproliferative Activity of 3,4‐Diarylpyrazole‐1‐carboxamide Derivatives Against Melanoma Cell Line.
Authors: El‐Gamal Mohammed I. , Choi Hong Seok , Cho Hae‐Guk , Hong Jun Hee , Yoo Kyung Ho , Oh Chang‐Hyun 
Published: February 2012

AbstractThe title compounds (III) and (IV) are screened for their antiproliferative activity against the A375 human melanoma cell line.
ChemInform Abstract: Synthesis of Mono‐ and Bis‐N‐heterocyclic Carbene Copper(I) Complexes via Decarboxylative Generation of Carbenes.
Authors: Le Gall Tatiana , Baltatu Sandra , Collins Shawn K. 
Published: February 2012

AbstractZwitterionic carboxylate derivatives (III) and (VII) are easily prepared from the corresponding imidazolium or imidazolinium tetrafluoroborates.
ChemInform Abstract: Discovery, Synthesis and SAR Analysis of Novel Selective Small Molecule S1P4‐R Agonists Based on a (2Z,5Z)‐5‐((Pyrrol‐3‐yl)methylene)‐3‐alkyl‐2‐ (alkylimino)thiazolidin‐4‐one Chemotype.
Authors: Roberts Edward , et al. et al. 
Published: February 2012

AbstractThe promising lead molecule (CYM50308) (I), a full spectrum selective S1P4‐R agonist, displays low nanomolecular S1P4 agonist activity and exquisite selectivity over the other S1P1‐3.5‐Rs family members.
ChemInform Abstract: One‐Pot Click Synthesis of 1N‐Alkyl‐4‐aryl‐1,2,3‐triazoles from Protected Arylalkynes and Alkyl Bromides.
Authors: Ladouceur Sebastien , Soliman Ahmed M. , Zysman‐Colman Eli 
Published: February 2012

AbstractA convenient protocol allows the synthesis of the target compounds via in situ alkyl azide formation, alkyne deprotection and subsequent copper‐catalyzed cycloaddition.
ChemInform Abstract: Enantioselective Palladium‐Catalyzed Allylic Substitution of Sodium Benzotriazolide.
Authors: Liu Wei , Zhang Dazhi , Zheng Shengcai , Yue Yinshuang , Liu Dongge , Zhao Xiaoming 
Published: February 2012

AbstractAsymmetric allylic allylation of sodium benzotriazolide (II) is efficiently catalyzed by a Pd—PHOX catalyst to afford a mixture of regioisomers (III) and (IV).
ChemInform Abstract: Synthesis of (Tetrahydrofuranyl)methyl‐1,2,3‐triazoles Through Alkyne‐Azide Cycloaddition Catalyzed by a Dithioic Acid Copper(I) Complex.
Authors: Velasco Bayardo E. , Fuentes Aydee , Gonzalez Carlos , Corona David , Garcia‐Orozco Ivan , Cuevas‐Yanez Erick 
Published: February 2012

AbstractA novel kind of dithioic acid copper(I) complex is employed as catalyst in an azide‐alkyne cycloaddition (CuAAC) reaction leading regioselectively to triazoles (III) and (VIII).
ChemInform Abstract: A Multicomponent Reaction Between α‐Substituted Acroleins, Nitroalkanes and Paraformaldehyde: Efficient Construction of Nitro δ‐Lactol.
Authors: Xiong Guoxi , Wei Mohui , Zhou Yirong , Li Yungui , Zhang Fanglin , Gong Yuefa 
Published: February 2012

AbstractA three‐component reaction followed by deoxygenation or oxidation offers an interesting synthesis of nitropyrans (IV) or analogous pyranones (IX).
ChemInform Abstract: Green Synthesis of Chromen‐2‐one Derivatives Catalyzed by L‐Proline.
Authors: Shi Chunling , Shi Da‐Qing 
Published: February 2012

AbstractA mild and efficient synthesis of the title compounds (III) via reaction of 4‐hydroxy‐6‐methyl‐pyran‐one with various substituted 2‐hydroxybenzaldehydes in water is described.
ChemInform Abstract: Aldol Condensation and Michael Addition of 4,4‐Diemthylcyclohexane‐1,3‐dione and Aromatic Aldehydes. Unconventional Substituent Effects.
Authors: Kaya Muharrem 
Published: February 2012

AbstractElectronic and steric effects on the aromatic aldehydes influence the regiochemistry of the title reaction.
ChemInform Abstract: Synthesis and Biological Evaluation of New 3‐(6‐Hydroxyindol‐2‐yl)‐5‐(phenyl) Pyridine or Pyrazine V‐Shaped Molecules as Kinase Inhibitors and Cytotoxic Agents.
Authors: Merour Jean‐Yves , et al. et al. 
Published: February 2012

AbstractThe new V‐shaped library which is represented by the general indole structure (VII) is obtained by using palladium catalyzed cross‐coupling reactions (Stille, Suzuki and Buchwald), mostly performed under microwave irradiation.
ChemInform Abstract: Mechanistic Studies on a New Catalyst System (CuI—NaHSO4·SiO2) Leading to the One‐Pot Synthesis of Imidazo[1,2‐a]pyridines from Reactions of 2‐Aminopyridines, Aldehydes, and Terminal Alkynes.
Authors: Mishra Sarita , Ghosh Rina 
Published: February 2012

AbstractThe procedure is highly suitable for the preparation of the clinically potent skeleton (28 examples).
ChemInform Abstract: Suzuki—Miyaura and Negishi Approaches to a Series of Forensically Relevant Pyridines and Pyrimidines.
Authors: Blachut Dariusz , Szawkalo Joanna , Czarnocki Zbigniew 
Published: February 2012

AbstractA variety of 5‐arylpyrimidines (III) (13 examples) is prepared by Suzuki—Miyaura coupling.
ChemInform Abstract: Synthesis and Biological Evaluation of Novel (Thio)Urea Derivatives as Potential Antitumor Agents.
Authors: Jin Chuanfei , Liang Yong‐Ju , He Hongwu , Fu Liwu 
Published: February 2012

AbstractCompound (Ve) displays more potent cytotoxic activities against KB, MGC‐803 and MCF‐7 tumor cell lines than reference 5‐fluorouracil.
ChemInform Abstract: Improvement of the Synthesis and Pharmacokinetic Properties of Chromenotriazolopyrimidine MDM2‐p53 Protein‐Protein Inhibitors.
Authors: Beck Hilary P. , et al. et al. 
Published: February 2012

AbstractA more robust and scalable synthetic route to chromenotriazolopyrimidine core (VI) is developed.
ChemInform Abstract: Palladium‐Catalyzed Direct 5‐Arylation of 1,3‐Dimethyluracil with Aryl Bromides: An Electrophilic Metalation—Deprotonation with Electrophilic Arylpalladium Intermediate.
Authors: Kim Ko Hoon , Lee Hyun Seung , Kim Jae Nyoung 
Published: February 2012

AbstractThe 6‐aryl derivatives (IV) are generated via a Heck‐type mechanism as minor products.
ChemInform Abstract: An Efficient Approach for the One‐Pot Synthesis of Ethyl 4‐Oxo‐4H‐benzo[d][1,3]oxazine‐2‐carboxylates.
Authors: Nikpour Farzad , Sharafi‐Kolkeshvandi Mahnaz , Bahmani Asrin 
Published: February 2012

AbstractA simple and convenient access to title compounds (III) is described.
ChemInform Abstract: A Convenient and General Palladium‐Catalyzed Carbonylative Coupling for the Synthesis of 2‐Arylbenzoxazinones.
Authors: Wu Xiao‐Feng , Schranck Johannes , Neumann Helfried , Beller Matthias 
Published: February 2012

AbstractA new Pd‐catalyzed double carbonylation of o‐aminoaryl bromides in the presence of aryl bromides is presented to furnish a diversity of benzoxazinones, e.g. (IV) and (IX), in good yields.
ChemInform Abstract: A New Synthetic Approach to Pentacyclic Ring, 6,7,14,15‐Tetrahydro[1,5]diazocino[1,2‐a:6,5‐a′]‐8‐dihydrodiindole.
Authors: Sripha Kittisak , Zlotos Darius Paul , Holzgrabe Ulrike , Ruchirawat Somsak 
Published: February 2012

AbstractThe construction of the new pentacyclic title ring system (VII) is presented.
ChemInform Abstract: Orally Bioavailable Imidazoazepanes as Calcitonin Gene‐Related Peptide (CGRP) Receptor Antagonists: Discovery of MK‐2918.
Authors: Paone Daniel V. , et al. et al. 
Published: February 2012

AbstractFused heterocyclic derivatives of telcagepant are explored with the aim to achieve a lower projected clinical dose.
ChemInform Abstract: Dialkylaluminum Hydride‐Promoted Cyclodimerization of Silylated 1,3‐Enynes via Skeletal Rearrangement.
Authors: Kinoshita Hidenori , Ishikawa Tomoyuki , Miura Katsukiyo 
Published: February 2012

AbstractSymmetrical tetrasubstituted benzenes (II) and (IV) are prepared as single regioisomers by a novel cyclodimerization reaction of silylated 1,3‐enynes (I) and (III) in the presence of a dialkylaluminum hydride.
ChemInform Abstract: An Efficient One‐Pot Synthesis of Trialkyl 2‐(Dialkoxyphosphoryl)ethene‐1,1,2‐tricarboxylates
Authors: Yavari Issa , Sanaeishoar Tayebeh , Azad Leila , Arab‐Salmanabadi Samira 
Published: February 2012

Abstractvia reaction of activated acetylenes, trialkyl phosphites, and alkyl cyanoformates under neutral reaction conditions
ChemInform Abstract: Stereoselective Synthesis of Dialkyl 2‐(Dialkoxyphosphoryl)‐3‐(3,5‐dioxo‐4‐phenyl‐[1,2,4]triazolidin‐1‐yl) Succinates
Authors: Mohebat Razieh , Moghaddam Mahtab Iravani , Motlagh Ramin Askari , Hassanabadi Alireza , Kalami‐Yazdi Masoud 
Published: February 2012

Abstractvia multicomponent reaction of acetylenedicarboxylates (III) with the N‐H acid triazolidine‐dione (I) in the presence of phosphites (II)
ChemInform Abstract: Direct Synthesis of Alkynylstannanes: ZnBr2 Catalyst for the Reaction of Tributyltin Methoxide and Terminal Alkynes.
Authors: Kiyokawa Kensuke , Tachikake Nodoka , Yasuda Makoto , Baba Akio 
Published: February 2012

AbstractRather than acting as a Lewis acid, ZnBr2 is transmetalated with Bu3SnOMe to give Zn(OMe)2, which is the key to the catalytic reaction.
ChemInform Abstract: Spicachlorantins G—J, New Lindenane Sesquiterpenoid Dimers from the Roots of Chloranthus spicatus.
Authors: Kim Sang‐Yong , Kashiwada Yoshiki , Kawazoe Kazuyoshi , Murakami Kotaro , Sun Han‐Dong , Li Shun‐Lin , Takaishi Yoshihisa 
Published: February 2012

AbstractFour new lindenane sesquiterpenoid dimers named spicachlorantins G—J (I)‐(III) are isolated from the roots of Chloranthus spicatus together with seven known compounds.
ChemInform Abstract: Crassocolides N—P, Three Cembranoids from the Formosan Soft Coral Sarcophyton crassocaule.
Authors: Wang Guey‐Horng , Huang Ho‐Cheng , Su Jui‐Hsin , Huang Chiung‐Yao , Hsu Chi‐Hsin , Kuo Yao‐Haur , Sheu Jyh‐Horng 
Published: February 2012

AbstractThe crassocolides N—P (I)—(III) are screened for their cytotoxic activity against KB, HeLa, and Daoy cells.
ChemInform Abstract: A Phosphine‐Mediated Synthesis of 1,4‐Oxazepine‐ and 1,5‐Oxazocine‐Based Sugar Hybrids from Deoxysugar Azides.
Authors: Kurhade Suresh E. , Salunkhe Videsh T. , Siddaiah V. , Bhuniya Debnath , Reddy D. Srinivasa 
Published: February 2012

AbstractThe process allows the preparation of biologically interesting heterocyclic systems of type (III) and (VI).
ChemInform Abstract: Reactions of Arylhydrazones of Dehydro‐L‐ascorbic Acid and of D‐Arabino‐2,3‐diulosono‐1,4‐lactone.
Authors: El‐Sekily M. A. , Mancy S. H. 
Published: February 2012

AbstractWith the aim to produce effective chemotherapeutic agents, pyrazole derivatives (I) ‐ (III) are synthesized from the carbohydrate‐derived arylhydrazones.
ChemInform Abstract: Hydrolysis of Sugars Using Magnetic Silica Nanoparticles with Sulfonic Acid Groups.
Authors: Takagaki Atsushi , Nishimura Masatoshi , Nishimura Shun , Ebitani Kohki 
Published: February 2012

AbstractA highly active and reusable solid catalyst, which can be recovered by facile magnetic separation, for the title reaction is presented.
ChemInform Abstract: Alkaloids from Chelidonium majus and Their Inhibitory Effects on LPS‐Induced NO Production in RAW264.7 Cells.
Authors: Min Byung Sun , et al. et al. 
Published: February 2012

AbstractThe new alkaloid (Ia), methyl 2′‐(7,8‐dihydrosanguinarine‐8‐yl)acetate, is isolated together with six known alkaloids.
ChemInform Abstract: Synthesis of New Oxabicyclo[3.3.0]octane Nucleoside Analogues with Pyrimidine Bases.
Authors: Tanase Constantin , Cocu Florea G. , Caproiu Miron T. , Draghici Constantin , Neagoe Ionela Victoria , Manda Gina 
Published: February 2012

AbstractThe synthesis of new isomeric nucleosides (III) and (IV) with an oxabicyclo[3.3.0]octane fragment in the sugar moiety is performed by Vorbruggen glycosylation.
ChemInform Abstract: Synthesis of 4‐[4‐(3‐Pyridinyl)imidazol‐1‐yl]‐1‐butylamine.
Authors: Cao Zhiling , Liu Bing , Liu Weiwei , Yao Guowei , Li Hongxia , Zou Ting 
Published: February 2012

AbstractThe title compound (VI), the side chain of the semisynthetic erythromycin derivative telithromycin, is obtained utilizing the HBr‐induced DMSO oxidation of 3‐acetylpyridine followed by direct transformation of the glyoxal formed into 4‐(3‐pyridyl)imidazole by a Debus reaction as the key steps.
ChemInform Abstract: A Simple Synthesis of the Pentacyclic Lamellarin Skeleton from 3‐Nitro‐2‐(trifluoromethyl)‐2H‐chromenes and 1‐Methyl(benzyl)‐3,4‐dihydroisoquinolines.
Authors: Korotaev Vladislav Yu. , Sosnovskikh Vyacheslav Ya. , Barkov Alexey Yu. , Slepukhin Pavel A. , Ezhikova Marina A. , Kodess Mikhail I. , Shklyaev Yurii V. 
Published: February 2012

AbstractA variety of lamellarin‐type pentacyclic compounds are prepared by use of Grob synthesis, i.e.
ChemInform Abstract: Synthesis of (R)‐(+)‐Tanikolide, a Toxic and Antifungal δ‐Lactone from the Marine Cyanobacterium Lyngbya majuscula.
Authors: Matsuo Keizo , Hikita Junko , Nishiwaki Keiji 
Published: February 2012

AbstractStarting from the known lactol (I) and using its stereogenic center at C‐4, title compound (VI), a brine‐shrimp toxic and antifungal marine metabolite, is obtained in a 5‐step procedure.
ChemInform Abstract: Bioactive C15 Acetogenins from the Red Alga Laurencia obtusa.
Authors: Ayyad Seif‐Eldin Nasr , Al‐Footy Khalid Omar , Alarif Walied Mohamed , Sobahi Tariq Rashad , Bassaif Salim Ahmed , Makki Mohamed Saleh , Asiri Abdullah Mohamed , Al Halawani Amani Yahya , Badria Adel Farid , Badria Farid Abd Al‐raheem 
Published: February 2012

AbstractThree new C15 acetogenins (I)—(III) are isolated from the ether extract of the red alga Laurencia obtusa along with one known compound.
ChemInform Abstract: 1‐Aryl‐5‐(1H‐pyrrol‐1‐yl)‐1H‐pyrazole‐3‐carboxamide: An Effective Scaffold for the Design of Either CB1 or CB2 Receptor Ligands.
Authors: Silvestri Romano , et al. et al. 
Published: February 2012

AbstractThe compound (Ia) shows CB1 receptor affinity and selectivity (Ki = 2.3 nM, SI = 163.6) superior to Rimonabant and AM251.
ChemInform Abstract: Ruthenium Active Catalytic States: Oxidation States and Methanol Oxidation Reactions
Authors: Blume Raoul , Haevecker Michael , Zafeiratos Spiros , Techner Detre , Knop‐Gericke Axel , Schloegl Robert , Gregoratti Luca , Barinov Alexei , Kiskinova Maya 
Published: February 2012

AbstractReview: 48 refs.
ChemInform Abstract: Charge Delocalization in Self‐Assembled Mixed‐Valence Aromatic Cation Radicals
Authors: Navale Tushar S. , Thakur Khushabu , Vyas Vijay S. , Wadumethrige Shriya H. , Shukla Ruchi , Lindeman Sergey V. , Rathore Rajendra 
Published: February 2012

AbstractReview: 63 refs.
The slow axonal transport of alpha‐synuclein—mechanistic commonalities amongst diverse cytosolic cargoes
Authors: Tang Yong , Das Utpal , Scott David A. , Roy Subhojit 
Published: February 2012

AbstractSlow axonal transport conveys perikaryally‐synthesized cytosolic proteins in a rate‐class called Slow Component‐b (SCb). One such protein—α‐synuclein—is largely conveyed in SCb, and is also a key player in a group of neurodegenerative diseases called synucleinopathies. Axonal transport defects of α‐synuclein have been hypothesized to play a role in synucleinopathies, but mechanisms moving α‐synuclein in slow axonal transport are unclear. Here we use a recently developed model‐system in our laboratory to visualize the slow transport of α‐synuclein, comparing it to another SCb protein synapsin. Despite differences inbiological properties and overallsolubility in axons, the anterograde transport of both SCb proteins was strikingly similar, suggesting commonalities in slow axonal transport mechanisms of seemingly diverse cytosolic cargoes. The data support a model where SCb proteins dynamically organize into ‘transport‐competent’ complexes that are conveyed via transient associations with other persistently‐moving cargoes (“mobile‐units”). The identity of the latter is yet unknown. Visualizing normal α‐synuclein transport may also open the door to studies of α‐synuclein transport in pathologic states. © 2012 Wiley Periodicals, Inc.
The Development of a New Multidimensional Depression Assessment Scale: Preliminary Results
Authors: Cheung Ho Nam , Power Michael J. 
Published: February 2012

Depression is a major problem for mental health. Empirical studies and clinical observations have shown that the symptoms of depression occur across four main domains—emotional, cognitive, somatic and interpersonal. However, commonly used depression assessment scales fail to address the evaluation of interpersonal symptoms, as summarized in this paper. Therefore, a new depression assessment scale, which aimed to evaluate all four domains of depressive symptomatology, was developed. In an initial analysis, a pilot 85‐item questionnaire containing possible depressive symptoms was distributed for evaluation to experts from different mental health professions, from which 52 items were subsequently selected for the new multidimensional depression assessment scale. One hundred community participants completed the questionnaire along with the Beck Depression Inventory‐II. The results indicated that the new depression scale had good psychometric properties. It was found to be reliable and valid for the assessment of depression severity and symptomatology, though it is emphasized that these data are only preliminary and based on a relatively healthy sample. Copyright © 2012 John Wiley & Sons, Ltd.Key Practitioner Message

Existing measures of depression are criticized for their lack of interpersonal items.
A new depression scale is presented that has a balance of interpersonal, emotional, cognitive and somatic items.
Examining the Link between Strategic Corporate Social Responsibility and Company Performance: An Analysis of the Best Corporate Citizens
Authors: Michelon Giovanna , Boesso Giacomo , Kumar Kamalesh 
Published: February 2012

ABSTRACTUsing KLD data on the performance of 188 companies over a three‐year period in seven areas of corporate social responsibility (CSR) – environment, community, corporate governance, diversity, employee relations, human rights, and product quality – this study examines whether CSR initiatives have a greater impact on company performance (CP) if the company prioritizes the CSR issues that matter most to it and approaches CSR initiatives in a strategic way, than if it approaches them based on generic rationale unrelated to the company's strategy. The results show that when a company pursues CSR initiatives that are linked to stakeholder preferences and allocates resources to these initiatives in a strategic way, the positive effect of its CSR initiatives on CP strengthens in terms of both market‐based and accounting‐based measures of performance. However, this relationship was not observed across the board for all of the seven areas of CSR. The main conclusion of this study is that companies need to link their CSR initiatives to the likely preferences of their stakeholders and undertake the corporate social actions that are relevant to the company's strategy. Copyright © 2012 John Wiley & Sons, Ltd and ERP Environment.
The 1‐Phenyl‐1‐(trimethylsilyl)ethyl Cation: An NMR Spectroscopic and Computational Study of the α‐Silyl Effect in Benzyl Cations
Authors: Kostenko Arseni , Müller Bernhard , Kaufmann Frank‐Peter , Apeloig Yitzhak , Siehl Hans‐Ullrich 
Published: February 2012

AbstractThe 1‐phenyl‐1‐(trimethylsilyl)ethyl cation is generated as a persistent species in solution and characterized experimentally by 1H, 13C, and 29Si NMR spectroscopy. The α‐silyl effect is elucidated by comparison with other benzyl cations, such as cumyl and 1‐phenylethyl cations. Concomitant quantum chemical calculations of structures, relative thermodynamic stabilities, chemical shifts, and the harmonic oscillator model of aromaticity (HOMA) indices are congruent with the analysis of the experimental NMR spectroscopy results; therefore, we conclude that, in benzyl cations, the α‐silyl substituent is stabilizing with respect to H, but destabilizing relative to a methyl group.
Electrochemical Oxidation Mechanisms of the Antioxidants Daidzein and 7‐Hydroxy‐4‐chromone
Authors: Fernandes Isabel P. G. , Oliveira Severino Carlos B. , Ghalkhani Masoumeh , Shahrokhian Saeed , Oliveira‐Brett Ana Maria 
Published: February 2012

AbstractThe electrochemical behavior of antioxidants daidzein (DZ) and 7‐hydroxy‐4‐chromone (7‐OH‐4‐CHM) was investigated. The oxidation of DZ is irreversible, pH‐dependent, and occurs in two steps, the first of 4′‐OH on the B‐ring and the second on the 7‐OH on the A‐ring. The oxidation of 7‐OH‐4‐CHM occurs on the 7‐OH on the A‐ring, is irreversible, pH‐dependent and proceeds in a single step. The DZ diffusion coefficient was calculated in pH 7.0 phosphate buffer to be DDZ=8.1×10−5 cm2 s−1. The detection limits of DZ and 7‐OH‐4‐CHM was calculated as LODDZ=0.08 µM and LOD7‐OH‐4‐CHM=0.13 µM.
Effect of polypropylene fibers on thermogravimetric properties of self‐compacting concrete at elevated temperatures
Authors: AL Qadi Arabi N. S. , Bin Mustapha Kamal Nasharuddin , Naganathan Sivakumar , AL‐Kadi Qahir N. S. 
Published: February 2012

ABSTRACTIn this study, the effect of polypropylene (PP) fibers on thermogravimetric parameters of self‐compacting concrete (SCC) containing indigenous materials was investigated experimentally and statistically. The mixes containing cement, water, fly ash, fine aggregate, coarse aggregate, and super plasticizer, with the addition of PP fibers (0%, 0.05%, 0.1%, and 0.15%) by volume of the mixtures, were prepared. The physical properties of SCC were determined at elevated temperatures (200, 400, and 600 °C) after cooling in the laboratory. Regression models were developed to determine the responses, and the optimum amount of 0.05% PP fibers by volume was measured. Copyright © 2012 John Wiley & Sons, Ltd.
An exceptional rocky shore preserved during Oligocene (Late Rupelian) transgression in the Upper Rhine Graben (Mainz Basin, Germany)
Authors: Rousse Stephane , Duringer Philippe , Stapf Karl R. G. 
Published: February 2012

The Early Oligocene (Late Rupelian) Alzey Formation (Mainz Basin, Upper Rhine Graben, Germany) records the development of a rocky coast depositional system during transgression. The formation unconformably overlies Permian bedrock across a composite transgressive ravinement surface. Exposure of the surface shows a succession of subplanar bedrock terraces, separated by near‐vertical risers. Terraces show a broad staircase geometry and display wave‐erosional features (notches, sea stacks, furrows). Detailed sedimentological and palaeoecological investigations reveal prograding beachface and shoreface depositional units that overlie terraces and are adjacent to risers.Terraces are interpreted as wave‐cut platforms, backed by palaeocliffs. The staircase architecture records the episodic landward migration of palaeoshorelines onto palaeotopographic highs during the Early Oligocene. Stacking patterns of gravelly beach and shoreface associated units (facies tracts) indicate successive episodes of terrace cutting, beach development, drowning and shoreline backstepping during an overall relative sea‐level rise.The exceptional preservation of the stair‐cased rocky shore may be attributed to a highly jerky rising relative sea‐level, as the result of the conjugated effects of rift‐controlled tectonic subsidence and eustatic sea‐level oscillations. Copyright © 2012 John Wiley & Sons, Ltd.
Stereoselective Total Synthesis of Stagonolide C
Authors: Yadav Jhillu S. , Mallikarjuna Reddy Nimmakayala , Venkateswar Rao N. , Rahman Md. Ataur , Prasad Attaluri R. 
Published: February 2012

AbstractA convergent and efficient total synthesis of stagonolide C (1), a phytotoxic metabolite, was achieved (Schemes 2 and 3) The synthesis exploited the high configuration control in the Prins cyclization along with alkene rearrangement and ring‐closing metathesis as key steps.