bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Characterization of Chloride‐Incorporated Dodecavanadate from Dicopper Complex of Macrocyclic Octadecavanadate.
Authors: Kurata Taisei , Hayashi Yoshihito , Isobe Kiyoshi 
Published: September 2010

AbstractThe copper atoms of (I) are easily removed by using gaseous HCN and in the presence of excess Cl‐ a new bowl‐shaped dodecavanadate anion with Cl at the center is formed.
ChemInform Abstract: Self‐Assembly of Alkali‐Uranyl‐Peroxide Clusters.
Authors: Nyman May , Rodriguez Mark A. , Campana Charles F. 
Published: September 2010

AbstractUranyl triperoxide, [UO2(O2)3]4‐, is known to self‐assemble into polyoxometalate‐like clusters that contain up to 60 uranyl cations bridged by peroxide ligands.
ChemInform Abstract: Hydroxylammonium Fluorometalates: Synthesis and Characterization of a New Fluorocuprate and Fluorocobaltate.
Authors: Kristl Matjaz , Dojer Brina , Kasunic Marta , Golobic Amalija , Jaglicic Zvonko , Drofenik Miha 
Published: September 2010

AbstractThe structures of the new compounds (II) and (IV) are determined by single crysal XRD.
ChemInform Abstract: A Green and Efficient Asymmetric Aldol Reaction Catalyzed by a Chiral Anion Modified Ionic Liquid.
Authors: Qian Yunbo , Zheng Xin , Wang Yongmei 
Published: September 2010

AbstractThe application of a chiral anion modified ionic liquid derived from L‐proline as a green and efficient organocatalyst for direct asymmetric aldol reactions is described.
ChemInform Abstract: Aromatic Motifs in the Design of Ephedra Ligands for Application in the Asymmetric Addition of Diethylzinc to Aldehydes and Diphenylphosphinoylimines.
Authors: Banerjee Sucharita , Camodeca Anthony J. , Griffin Gregory G. , Hamaker Christopher G. , Hitchcock Shawn R. 
Published: September 2010

AbstractA range of ephedrine‐like ligands is prepared varying mainly the N‐benzyl moiety of original ephedrine.
ChemInform Abstract: Asymmetric Hydrogenation of Ketones Catalyzed by a Ruthenium(II)‐indan—Ambox Complex.
Authors: Li Wei , Hou Guohua , Wang Chunjiang , Jiang Yutong , Zhang Xumu 
Published: September 2010

AbstractHighly enantioselective asymmetric hydrogenation of a variety of aromatic and aliphatic ketones (20 examples) is achieved using a novel Ru(II) indan‐ambox complex.
ChemInform Abstract: Reduction Processes Biocatalyzed by Vigna unguiculata.
Authors: Bizerra Ayla M. C. , de Gonzalo Gonzalo , Lavandera Ivan , Gotor‐Fernandez Vicente , de Mattos Marcos Carlos , de Oliveira Maria da Conceicao F. , Lemos Telma L. G. , Gotor Vicente 
Published: September 2010

AbstractWhole cells of the brazilian beans Vigna unguiculata are successfully applied as biocatalyst in the asymmetric reduction of aromatic (I), (III) and aliphatic ketones as well as β‐keto esters (V).
ChemInform Abstract: Organocatalyzed Enantioselective Michael Additions of Nitroalkanes to Enones by Using Primary—Secondary Diamine Catalysts.
Authors: Yang Ying‐Quan , Chen Xin‐Kuan , Xiao Hua , Liu Wen , Zhao Gang 
Published: September 2010

AbstractThe title reaction affords the corresponding Michael adducts with high yields and enantioselectivities.
ChemInform Abstract: A New Synthesis of Novel Tricyclic 2(5H)‐Furanone Heterocycles from 3,4,5‐Trichloro‐2(5H)‐furanone.
Authors: Ren Jian , Ma Dan‐Dan , Sha Yu , Li Feng , Cheng Mao‐Sheng 
Published: September 2010

AbstractStarting from mucochloric acid (I) new heterocycles of type (IV), (VI), and (VII) are prepared.
ChemInform Abstract: Elusive Ethynyl Azides: Trapping by 1,3‐Dipolar Cycloaddition and Decomposition to Cyanocarbenes.
Authors: Banert Klaus , Hagedorn Manfred , Wutke Jens , Ecorchard Petra , Schaarschmidt Dieter , Lang Heinrich 
Published: September 2010

AbstractAlthough they decompose rapidly to produce cyanocarbenes, ethynyl azides are generated from (chloroethynyl)arenes (I) and (V) and trapped for the first time by 1,3‐dipolar cycloaddition with cyclooctyne (II).
ChemInform Abstract: Radical Alkylations of Alkyl Halides and Unactivated C—H Bonds Using Vinyl Triflates.
Authors: Lee Jin Young , Lim Kyoung‐Chan , Meng Xiangjian , Kim Sunggak 
Published: September 2010

AbstractRadical‐mediated allylations of alkyl halides, ethers and alkanes are achieved using triflates as radical acceptors.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Arylhalogenation of Alkenes: Synthetic Scope and Mechanistic Insights.
Authors: Kalyani Dipannita , Satterfiled Andrew D. , Sanford Melanie S. 
Published: September 2010

AbstractArylchlorination and arylbromination of aliphatic and aromatic olefins is investigated.
ChemInform Abstract: Photodesulfinylation of Optically Active N‐Sulfinyl Amines.
Authors: Davis Franklin A. , Ramachandar Tokala , Zhang Yanfeng , Chai Jing , Qui Hui , Deng Jianghe , Velvadapu Venkata 
Published: September 2010

AbstractThe reaction gives the corresponding amines without racemization and does not require acidic or basic conditions.
ChemInform Abstract: Enantioselective Synthesis of 3‐Azabicyclo[4.1.0]heptenes and 3‐Azabicyclo[3.2.0]heptenes by Ir‐Catalyzed Asymmetric Allylic Amination of N‐Tosyl Propynylamine and Pt‐Catalyzed Cycloisomerization.
Authors: Xia Ji‐Bao , Liu Wen‐Bo , Wang Tian‐Min , You Shu‐Li 
Published: September 2010

AbstractHighly regio‐ and enantioselective Ir‐catalyzed allylic amination reactions of N‐tosyl propynylamines with allylic carbonates result in the formation of N‐tosyl allylpropynylamines.
ChemInform Abstract: Development of N,N‐Bis(perfluoroalkanesulfonyl)squaramides as New Strong Broensted Acids and Their Application to Organic Reactions.
Authors: Cheon Cheol Hong , Yamamoto Hisashi 
Published: September 2010

AbstractN,N′‐Bis(triflyl)squaramide (Ia) is prepared and successfully applied in various Mukaiyama and Mukaiyama—Michael reactions.
ChemInform Abstract: Sodium Dithionite Initiated Fluoroalkylation of Trimethoxybenzenes, Mesitylene and Pyrroles with BrCF2CF2Br.
Authors: Dmowski Wojciech , Piasecka‐Maciejewska Krystyna 
Published: September 2010

AbstractThe sodium dithionite‐initiated reaction of various substrates with BrCF2CF2Br can only be successfully applied to the most electron‐rich compounds of type (I), (VI) and (XII).
ChemInform Abstract: Catalytic Use of a Soluble Organoindium(III) Species for Allylation and Crotylation of Ketones with Boronates.
Authors: Yamaguchi Miyuki , Morita Naohide , Schneider Uwe , Kobayashi Shu 
Published: September 2010

AbstractThe first catalytic use of a main group 13 metal amide, In(NTms2)3, in organic synthesis is reported.
ChemInform Abstract: Copper‐Catalyzed Multicomponent Coupling of Organoindium Reagents with Nitrogen‐Containing Aromatic Heterocycles.
Authors: Beveridge Ramsay E. , Black Daniel A. , Arndtsen Bruce A. 
Published: September 2010

AbstractThe copper‐catalyzed coupling of organoindium reagents with nitrogen‐containing aromatic heterocycles and chloroformates is described.
ChemInform Abstract: Efficient Solid/Liquid Phase‐Transfer Catalytic Diazo Transfer Synthesis.
Authors: Jaszay Zsuzsa M. , Pham Truong Son , Goenczi Katalin , Petnehazy Imre , Toeke Laszlo 
Published: September 2010

AbstractThe presented PTC method also provides sensitive diazo compounds such as phosphonyl and phosphinyl derivatives (IId) and (IIe) in excellent yield and purity.
ChemInform Abstract: High‐Yielding Synthesis of Weinreb Amides via Homogeneous Catalytic Carbonylation of Iodoalkenes and Iodoarenes.
Authors: Takacs Attila , Petz Andrea , Kollar Laszlo 
Published: September 2010

AbstractPhosphine/palladium ratio has to be 2/1 since one equivalent of phosphine acts as a reductant of Pd(II) to Pd(0) and the other one is coordinating.
ChemInform Abstract: Combined InCl3‐ and Amine‐Catalyzed Intramolecular Addition of α‐Disubstituted Aldehydes onto Unactivated Alkynes.
Authors: Montaignac Benjamin , Vitale Maxime R. , Michelet Veronique , Ratovelomanana‐Vidal Virginie 
Published: September 2010

AbstractInCl3 in combination with an amine catalyzes the cyclization of formylalkynyl substrates to afford cyclopentanone products and the pyrrolidine (IV).
ChemInform Abstract: N‐Triflylthiophosphoramide Catalyzed Enantioselective Mukaiyama Aldol Reaction of Aldehydes with Silyl Enol Ethers of Ketones.
Authors: Cheon Cheol Hong , Yamamoto Hisashi 
Published: September 2010

AbstractExcellent yields and good to excellent enantioselectivities are obtained for open‐chain silyl ethers (I) and (V).
ChemInform Abstract: An Alternative Route for Synthesis of o‐Trifluoroacetylanilines as Useful Fluorine‐Containing Intermediates.
Authors: Zhu Lingjian , Miao Zhenyuan , Sheng Chunquan , Yao Jianzhong , Zhuang Chunlin , Zhang Wannian 
Published: September 2010

AbstractA regioselective method is used for the preparation of title compounds, e.g. (III), which are potential key intermediates for the synthesis of HIV reverse transcriptase inhibitors.
ChemInform Abstract: Conjugate Addition of Lithium N‐tert‐Butyldimethylsilyloxy‐N‐(α‐methylbenzyl)amide: Asymmetric Synthesis of β2,2,3‐Trisubstituted Amino Acids.
Authors: Bentley Scott A. , Davies Stephen G. , Lee James A. , Roberts Paul M. , Russell Angela J. , Thomson James E. , Toms Steven M. 
Published: September 2010

AbstractChiral isoxazolidin‐5‐ones are prepared with high diastereoselectivities from α,β‐unsaturated esters and (II).
ChemInform Abstract: Solvent‐Free Mukaiyama and Mukaiyama—Michael Vinylogous Reactions of a Dioxinone‐Derived Silyl Enol Ether Promoted by Lewis Bases.
Authors: Scettri Arrigo , De Sio Vincenzo , Villano Rosaria , Manzo Patrizia , Acocella Maria Rosaria 
Published: September 2010

AbstractThe cyclic ether (I) reacts in the presence of PNO with a variety of aldehydes and ketones the give vinylogous aldols as masked δ‐hydroxy‐β‐ketoesters.
ChemInform Abstract: Copper(II)‐Catalyzed Esterification of Arenecarboxylic Acids with Aryl‐ and Vinyl‐Substituted Trimethoxysilanes.
Authors: Luo Fang , Pan Changduo , Qian Pengcheng , Cheng Jiang 
Published: September 2010

AbstractThe method represents a practical alternative without the need of acyl chlorides and phenols as substrates.
ChemInform Abstract: Selenium‐Catalyzed Oxidative Carbonylation of Aniline and Alcohols to N‐Phenylcarbamates.
Authors: Zhang Xiaopeng , Jing Huanzhi , Zhang Guisheng 
Published: September 2010

AbstractA facile one‐pot, phosgene‐free synthesis of N‐phenylcarbamates (IV) is demonstrated.
ChemInform Abstract: Cationic Pd(II)/Bipyridine‐Catalyzed Conjugate Addition of Arylboronic Acids to β,β‐Disubstituted Enones: Construction of Quaternary Carbon Centers.
Authors: Lin Shaohui , Lu Xiyan 
Published: September 2010

AbstractLow amounts of the complex PBB allow the preparation of various β‐disubstituted cyclohexanone derivatives and cyclopentanone (IIIb) in good to excellent yield.
ChemInform Abstract: Development of Binaphthyl‐Based Chiral Dienes for Rhodium(I)‐Catalyzed Asymmetric Arylation of N,N‐Dimethylsulfamoyl‐Protected Aldimines.
Authors: Cao Ziping , Du Haifeng 
Published: September 2010

AbstractTen ligands bearing aromatic substituents are prepared and the anisyl derivative (I) is found to be the most efficient one.
ChemInform Abstract: A Convenient Synthesis of (Z)‐4‐Hydroxy‐N‐desmethyltamoxifen (Endoxifen).
Authors: Fauq Abdul H. , Maharvi Ghulam M. , Sinha Dola 
Published: September 2010

AbstractA convenient synthesis of (Z)‐4‐hydroxy‐N‐desmethyltamoxifen (endoxifen) (IV), a potent antiestrogenic metabolite of the anticancer drug tamoxifen, is presented.
ChemInform Abstract: Fast Copper‐, Ligand‐ and Solvent‐Free Sonogashira Coupling in a Ball Mill.
Authors: Thorwirth Rico , Stolle Achim , Ondruschka Bernd 
Published: September 2010

AbstractPalladium acetate as catalyst in combination with SiO2 as a grinding auxiliary allow for the chemoselective transformation of aryl iodides.
ChemInform Abstract: Palladium‐Catalyzed Direct Cross‐Coupling Reaction Between Indenes and Electron‐Deficient Alkenes.
Authors: Xu Yun‐He , Wang Wee‐Jian , Wen Zhen‐Kang , Hartley Joshua Jonathan , Loh Teck‐Peng 
Published: September 2010

AbstractThe simple procedure affords the desired dienes in moderate to low yields.
ChemInform Abstract: An Open‐and‐Shut Strategy: Preparation of Benzofused Indans by Ring‐Opening of a Vinylogous Acyl Triflate and Metal‐Catalyzed Asao—Yamamoto Benzannulation.
Authors: Jones David M. , Dudley Gregory B. 
Published: September 2010

AbstractA combination of tandem addition—fragmentation of vinylogous acyl triflates (II), (XII) towards iodobenzene derivatives and intramolecular benzannulation of o‐alkynylphenyl ketones (VI) and (XIII) is successfully applied as novel strategy for the synthesis of benzofused indans.
ChemInform Abstract: Synthesis of Bishomobenzoctamine 2‐(9,10‐Dihydro‐9,10‐propanoanthracen‐9‐yl)‐N‐methylethanamine (IX)
Authors: Karama Usama , Al‐Saidey Adel , Almansour Abdel Rahman 
Published: September 2010

Abstract[via an ultrasound‐assisted [3 + 4] cycloaddition of allylanthracene (III) with tetrabromoacetone].
ChemInform Abstract: Cyclopentadienylcobalt‐Mediated Intermolecular Cycloaddition of α,ω‐Diynes to (Cyclo)alkenes: Synthesis of Linearly Fused Oligocycles and Extension to Enantiomerically Pure (6aR,10aR)‐Dihydroanthracyclinones.
Authors: Aubert Corinne , Gandon Vincent , Han Sangdon , Johnson Barry M. , Malacria Max , Schoemenauer Sten , Vollhardt K. Peter C. , Whitener Glenn D. 
Published: September 2010

AbstractThe [2 + 2 + 2] photocycloaddition of diynes with a broad spectrum of nonactivated 1,2‐disubstituted alkenes is investigated in the presence of CpCo(CO)2.
ChemInform Abstract: Asymmetric Epoxidation of 2‐Arylidene‐1,3‐diketones: Facile Access to Synthetically Useful Epoxides.
Authors: Russo Alessio , Lattanzi Alessandra 
Published: September 2010

AbstractThe first asymmetric epoxidation of title arylidenediketones, e.g. (I), (IV) or (VI), is presented.
ChemInform Abstract: Isothiourea‐Mediated Stereoselective C‐Acylation of Silyl Ketene Acetals.
Authors: Woods Philip A. , Morrill Louis C. , Lebl Tomas , Slawin Alexandra M. Z. , Bragg Ryan A. , Smith Andrew D. 
Published: September 2010

AbstractThe optimized conditions are applied to the preparation of 22 derivatives.
ChemInform Abstract: Application of Dicyclohexyl‐(S)‐trimethoxyphenyl Phosphine·HBF4 Salt for the Highly Selective Suzuki Coupling of the C—Cl Bond in β‐Chlorobutenolides Over the More Reactive Allylic C—O Bond.
Authors: Lue Bo , Fu Chunling , Ma Shengming 
Published: September 2010

AbstractA newly developed ligand is used for the selective Suzuki coupling of β‐chlorobutenolides with arylboronic acids giving products with high enantioselectivities.
ChemInform Abstract: PEG 400 as a Reusable Solvent for 1,4‐Dipolar Cycloadditions via a Three‐Component Reaction.
Authors: Reddy B. V. Subba , Somashekar D. , Reddy A. Mallikarjun , Yadav J. S. , Sridhar Balasubramanian 
Published: September 2010

AbstractPolyethylene glycol 400 represents an efficient reaction medium for the cycloaddition of α,β‐unsaturated aromatic aldehydes with zwitterions derived from isocyanides and dialkyl acetylenedicarboxylates to give styryl‐ and chromenylfurans in good yields.
ChemInform Abstract: A Synthesis of β‐Allyl Substituted Isotetronic Acid Derivatives via Thermal Claisen Rearrangement.
Authors: Ma Xiaping , Li Zhiming , Wang Quanrui 
Published: September 2010

AbstractThe Claisen rearrangement of O‐allyl substituted isotetronic acids of type (I), (III), or (V) is described.
ChemInform Abstract: Asymmetric Synthesis of Thiadecalins via an Organocatalytic Triple Cascade/ Sulfa‐Michael Sequence.
Authors: Enders Dieter , Schmid Bertram , Erdmann Nico , Raabe Gerhard 
Published: September 2010

AbstractA two‐step route consisting of a triple domino reaction of aldehydes (I) or (VI), β‐nitrostyrenes and α,β‐unsaturated aldehydes (III) or (IX) followed by an intermolecular sulfa‐Michael addition offers a convenient synthesis to the thiadecalin skeleton and a related benzothiophene (VIII).
ChemInform Abstract: Synthesis and Antimicrobial Evaluation of Some New Thiophene Derivatives.
Authors: Khalil A. M. , Berghot M. A. , El‐Ghani Ghada E. Abd , Gouda M. A. 
Published: September 2010

AbstractRepresentative compounds are evaluated for their antibacterial (Bacillus thuringiensis, Klebsiella pneumoniae) and antifungal (Botrytis fabae, Fusarium oxysporum) activities.
ChemInform Abstract: Novel 1,3,5‐Triphenyl‐2‐pyrazolines as Antiinfective Agents.
Authors: Sivakumar P. M. , Seenivasan S. Prabhu , Kumar Vanaja , Doble Mukesh 
Published: September 2010

AbstractA series of 16 compounds of type (III) or (IV) are tested as anti‐infective agents.
ChemInform Abstract: Synthesis of 4‐Aryl‐1H‐pyrazoles by Suzuki—Miyaura Cross Coupling Reaction Between 4‐Bromo‐1H‐1‐tritylpyrazole and Arylboronic Acids.
Authors: Ichikawa Hayato , Nishioka Miho , Arimoto Masao , Usami Yoshihide 
Published: September 2010

AbstractA general method is presented for the preparation of title compounds (III).
ChemInform Abstract: Potassium Dihydrogen Phosphate Catalyzed One‐Pot Synthesis of 2,4,5‐Triaryl‐1H‐imidazoles.
Authors: Joshi Ratnadeep S. , Mandhane Priyanka G. , Shaikh Mohammad U. , Kale Rajesh P. , Gill Charansingh H. 
Published: September 2010

AbstractCompared to benzoin (III), benzil (I) affords marginally higher yields in shorter reaction times.
ChemInform Abstract: Synthesis of 2,4,5‐Triarylimidazoles in Aqueous Solution, under Microwave Irradiation.
Authors: Chauveau Edouard , Marestin Catherine , Schiets Frederic , Mercier Regis 
Published: September 2010

AbstractThe three‐component reaction presented proceeds expeditiously and with excellent yields, affording the title compounds (III) by simple filtration.
ChemInform Abstract: Versatile Synthesis of Quaternary 1,3‐Oxazolidine‐2,4‐diones and Their Use in the Preparation of α‐Hydroxyamides.
Authors: Merino Omar , Santoyo Blanca M. , Montiel Luisa E. , Jimenez‐Vazquez Hugo A. , Zepeda L. Gerardo , Tamariz Joaquin 
Published: September 2010

AbstractA new two‐step sequence involves reaction of α‐ketols with isocyanates and subsequent oxidative cleavage of the exocyclic double bond according to A) or B) to give the title compounds.
ChemInform Abstract: Gold‐Catalyzed Cyclization and Subsequent Arylidene Group Transfer of O‐Propioloyl Oximes.
Authors: Nakamura Itaru , Okamoto Masashi , Terada Masahiro 
Published: September 2010

AbstractThe simple procedure allows the cycloisomerization of (E)‐oximes derived from aromatic aldehydes (or ketones) to 4‐arylideneisoxazolones with high (Z)‐selectivity.The substrate (V) bearing an alkyl group does not react but decomposes spontaneously.
ChemInform Abstract: Direct Synthesis of Trisubstituted Isoxazoles Through Gold‐Catalyzed Domino Reaction of Alkynyl Oxime Ethers.
Authors: Ueda Masafumi , Sato Aoi , Ikeda Yuki , Miyoshi Tetsuya , Naito Takeaki , Miyata Okiko 
Published: September 2010

AbstractThe novel method allows the approach to various trisubstituted isoxazoles, which may be of interest in natural product synthesis and as biological substances.
ChemInform Abstract: An Efficient Synthesis of Highly Functionalized 4H‐Pyrano[3,2‐d]isoxazoles via Isocyanide‐Based Three‐Component Reaction.
Authors: Esmaeili Abbas Ali , Hosseinabadi Rahele , Habibi Azizollah 
Published: September 2010

AbstractZwitterionic intermediates generated from isocyanides and diesters (II) react with isoxazolone (I) to produce the title compounds (IV) in good yields.
ChemInform Abstract: A Highly Efficient Methodology for 5‐Methyl‐3‐aryl‐2‐thiooxazolidin‐4‐ones Using Lithium Perchlorate in DIPEA Mediated Synthesis.
Authors: Khatik Gopal L. , Pal Anang , Apsunde Tushar D. , Nair Vipin A. 
Published: September 2010

AbstractAryl isothiocyanates (III) are converted to the title compounds (V) by treating with ethyl lactate (IV) in the presence of a base and a catalytic amount of lithium perchlorate.
ChemInform Abstract: Copper(I)‐Catalyzed Azide—Alkyne Cycloadditions in Ionic Liquids under Amine‐Free Conditions.
Authors: Vecchi Alessandra , Chambery Angela , Chiappe Cinzia , Marra Alberto , Dondoni Alessandro 
Published: September 2010

AbstractThe commercially available polyoxygenated ionic liquid AMMOENG 100 promotes the reaction of structurally diverse azides with different terminal alkynes without the need for amines as an additive.
ChemInform Abstract: Copper Nitride Nanoparticles Supported on a Superparamagnetic Mesoporous Microsphere for Toxic‐Free Click Chemistry.
Authors: Chi Dae Yoon , et al. et al. 
Published: September 2010

AbstractCopper nitride nanoparticles supported on a mesoporous superparamagnetic silica microsphere exhibit superior catalytic activity toward the Huisgen cycloaddition of azides and alkynes (15 examples).
ChemInform Abstract: Lewis Acid Catalyzed Cycloaddition of Methylenecyclopropanes with Salicylaldehydes.
Authors: Jiang Min , Shi Min 
Published: September 2010

AbstractTreatment of salicylaldehydes with triethyl orthoformate generates o‐quinonemethide analogues which undergo efficient Lewis acid catalyzed cycloaddition with methylenecyclopropanes to produce the desired benzopyran products.
ChemInform Abstract: Synthesis of Chromeno[3,4‐b]pyrrol‐4(3H)‐ones by Cyclocondensation of 1,3‐Bis(trimethylsilyloxy)buta‐1,3‐dienes with 4‐Chloro‐3‐nitrocoumarin.
Authors: Fatunsin Olumide , Iaroshenko Viktor O. , Dudkin Sergii , Shkoor Mohanad , Volochnyuk Dmitro , Gevorgyan Ashot , Langer Peter 
Published: September 2010

AbstractThe highly efficient two‐step sequence is suitable for application in medicinal chemistry.
ChemInform Abstract: The Discovery and Structure—Activity Relationships of 2‐(Piperidin‐3‐yl)‐1H‐Benzimidazoles as Selective, CNS Penetrating H1‐Antihistamines for Insomnia.
Authors: Beaton Graham , et al. et al. 
Published: September 2010

AbstractA series of novel benzimidazoles (VII) are synthesized and identified as potent and selective H1‐antihistamines with reduced hERG activity.
ChemInform Abstract: Selective and Facile Palladium‐Catalyzed Amination of 2‐Fluoro‐4‐iodopyridine in the 4‐Position under Microwave Conditions.
Authors: Koley Moumita , Schnuerch Michael , Mihovilovic Marko D. 
Published: September 2010

AbstractThe microwave protocol is superior to previous procedures due to drastically shorter reaction times and significantly decreased amounts of base.
ChemInform Abstract: Facile Synthesis and Antibacterial, Antitubercular, and Anticancer Activities of Novel 1,4‐Dihydropyridines.
Authors: Sirisha Kalam , Achaiah Garlapati , Reddy Vanga Malla 
Published: September 2010

AbstractImproved Hantzsch syntheses under different conditions are applied for the preparation of a series of heteroaryl substituted DHP′s.
ChemInform Abstract: A New Synthesis of (R)‐(‐)‐Sumanirole (PNU‐95666E).
Authors: Jean‐Gerard Ludivine , Mace Frederic , Dentel Helene , Ngo Anh Ngoc , Collet Sylvain , Guingant Andre , Evain Michel 
Published: September 2010

AbstractThe title compound (VI) was investigated in clinical studies for the treatment of Parkinson′s disease and found to be unsuitable.
ChemInform Abstract: Synthesis of 7‐Benzyl‐5‐(piperidin‐1‐yl)‐6,7,8,9‐tetrahydro‐3H‐pyrazolo[3,4‐c] [2,7]naphthyridin‐1‐ylamine and Its Analogues as Bombesin Receptor Subtype‐3 Agonists.
Authors: Guo Cheng , et al. et al. 
Published: September 2010

AbstractA concise synthesis of the title compound (VI) in gram quantity is achieved starting from commercially available materials.
ChemInform Abstract: The Synthesis of 3‐Pyrazinyl‐imidazo[1,2‐a]pyridines from a Vinyl Ether.
Authors: Collins Michael Raymond , Huang Qinhua , Ornelas Martha A. , Scales Stephanie A. 
Published: September 2010

AbstractTreatment of vinyl ether (II) with NBS and water generates the brominated hemiacetal intermediate (III) which reacts with aminopyridines to afford the pharmaceutically important skeleton (IV) in moderate yields.
ChemInform Abstract: Concise Copper‐Catalyzed One‐Pot Tandem Synthesis of Benzimidazo[1,2‐b]isoquinolin‐11‐one Derivatives.
Authors: Lu Juyou , Gong Xiaoyu , Yang Haijun , Fu Hua 
Published: September 2010

AbstractTitle compounds (III) are formed via coupling of 2‐halo‐N‐(2‐halophenyl)benzamides (I) with 2‐cyanoacetates or malononitrile (II).