bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motor Imagery Practice to Improve Respiratory and Cough Function
Authors: Donohue Cara 
Published: February 2025

Abstract
Motor imagery practice (MP), or visualizing performing a task without executing it, is an effective intervention for the limbs and tongue. However, MP of expiratory muscle strength training (EMST) and voluntary cough (VC) has not been explored. We examined the feasibility and impact of MP of VC and EMST on pulmonary and cough function in twenty community-dwelling adults. Participants underwent two baseline research evaluations of maximum expiratory and inspiratory pressure (MEP, MIP), forced vital capacity (FVC), voluntary peak expiratory flow rate (PEF), and cough spirometry. After the second research evaluation, participants underwent five weeks of MP of VC or EMST (alternating assignment, 25 repetitions, 70% training load, daily) at home with weekly telehealth sessions. Participants underwent post-treatment research evaluations of MEP, MIP, FVC, PEF, cough spirometry, and the Exercise Therapy Burden Questionnaire (ETBQ). Treatment adherence and telehealth attendance were tracked. Descriptives and Wilcoxon signed rank tests were performed. MP adherence was 95% and telehealth attendance was 91%. Median (IQR) ETBQ scores were 8 (1, 15), indicating minimal burden. Across both MP groups, increases in PEF from a handheld device (+ 13.7, 95% CI: 1.8, 25.6, p = 0.03) and from cough spirometry (+ 0.71, 95% CI: 0.05, 1.4, p = 0.04) were observed. Increases in PEF from cough spirometry (+ 1.00, 95% CI: 0.12, 1.9, p = 0.04) were observed for the MP VC group. Preliminary data demonstrate MP of VC and EMST is feasible and improves voluntary cough in community-dwelling adults. Future research is needed in larger sample sizes and patient populations with pulmonary, cough, and swallowing impairments.
Health-related quality-of-life outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review
Authors: Cook William H. , Khalil Fareha , Gillespie Conor S. , Helmy Adel E. 
Published: February 2025

Abstract
WHO grade 2 and 3 meningioma constitute approximately 20% of all meningioma. The lower incidence of these more aggressive meningiomas has led to under-representation of clinical outcomes in the literature. It is hypothesised that patients with grade 2 or 3 meningiomas are disabled by tumour and treatment morbidity, contributing to lower health-related quality-of-life (HRQoL). A PRISMA-compliant systematic review was conducted (PROSPERO CRD42023441009). MEDLINE, EMBASE, and Cochrane Library databases were searched between inception and September 2023. Studies of adults (> 16 y.o.) with histologically-proven WHO grade 2 and 3 cranial meningioma who underwent a combination of surgery, radiotherapy, and stereotactic radiosurgery and had HRQoL outcome data were included. Primary outcome was HRQoL. Fifteen studies were included. HRQoL was measured with 10 different tools, three of which have been validated in meningioma patients. Only two studies exclusively reported on WHO grade 2 and 3 meningioma and four further studies considered WHO grade in statistical analysis. WHO grade 2 and 3 meningioma were associated with reduced HRQoL in two studies that reported direct comparison and no difference in another two. Psychological domains were reduced in most studies compared to normative data or controls including in one of the two studies reporting on WHO grade 2 and 3 tumours exclusively. This systematic review highlights the need for prospective studies of more patients with grade 2 and 3 meningioma with validated meningioma-specific HRQoL tools. The current literature is limited by the small proportion of patients within reported studies, and heterogenous and poorly reported management paradigms.
The role of winter cereals as cold-weather refuge for Taiga Bean Geese Anser fabalis fabalis wintering in Denmark
Authors: Vergin Lisa , Clausen Kevin Kuhlmann , Madsen Jesper 
Published: February 2025

Abstract
Suitable foraging habitats are essential for migratory birds during their wintering period, as well as alternative staging areas to which they can relocate, e.g. due to changes in weather conditions. This study focusses on the habitat use of Taiga Bean Geese (Anser fabalis fabalis) at a wintering site in Denmark, that is particularly important for the geese during cold spells. Recent plans for energy constructions in this area have raised concerns about the potential loss of agricultural foraging habitats for geese. To better understand the role and importance of the different habitats, we analysed habitat use and energy intake on both agricultural fields and semi-natural pastures. We investigated the proportional use of winter cereal fields of GPS-tagged Taiga Bean Geese in relation to daily average temperatures and collected food and faecal samples on winter cereals and pastures during both cold and mild weather condition to investigate possible differences in energetic intake. The results showed an increased use of winter cereals when temperatures dropped. Moreover, during cold periods, the geese appeared to only be able to maintain a positive energy balance on winter cereals, which could explain the increased use in low temperatures. In mild situations, pastures seemed to also cover the energy requirements of wintering Taiga Bean Geese, with an energy assimilation efficiency similar to what was found on winter cereals. Our study underlines the importance of ensuring the availability of refuges that can meet the energetic needs of geese across different weather situations, especially when planning constructions that may affect those resources.
A game-theoretic approach for hierarchical epidemic control
Authors: Jia Feiran , Mate Aditya , Li Zun , Jabbari Shahin , Chakraborty Mithun , Tambe Milind , Wellman Michael P. , Vorobeychik Yevgeniy 
Published: February 2025

Abstract
We design and analyze a multi-level game-theoretic model of hierarchical policy interventions for epidemic control, such as those in response to the COVID-19 pandemic. Our model captures the potentially mismatched priorities among a hierarchy of policy-makers (e.g., federal, state, and local governments) with respect to two cost components that have opposite dependence on the policy strength—post-intervention infection rates and the socio-economic cost of policy implementation. Additionally, our model includes a crucial third factor in decisions: a cost of non-compliance with the policy-maker immediately above in the hierarchy, such as non-compliance of counties with state-level policies. We propose two novel algorithms for approximating solutions to such games. The first is based on best response dynamics (BRD) and exploits the tree structure of the game. The second combines quadratic integer programming (QIP), which enables us to collapse the two lowest levels of the game, with the best response dynamics. We experimentally characterize the scalability and equilibrium approximation quality of our two approaches against model parameters. Finally, we conduct experiments in simulations based on both synthetic and real-world data under various parameter configurations and analyze the resulting (approximate) equilibria to gain insight into the impact of decentralization on overall welfare (measured as the negative sum of costs) as well as emergent properties like social welfare, free-riding, and fairness in cost distribution among policy-makers.
Parental Bonding and Dyadic Adjustment: The Mediating Role of the Differentiation of Self
Authors: Lampis Jessica , Busonera Alessandra , Tommasi Marco 
Published: February 2025

Abstract
Emotional connections with significant caregivers greatly influence how individuals perceive themselves and others in intimate relationships. Grounded in the differentiation of self theory, this study examined factors that contribute to the quality of couple relationships. It investigated the association between parental attachment bonds and the quality of romantic attachments, as well as whether differentiation of self processes mediate these relationships. The study involved 480 participants in couple relationships, with an average age of 35.4 years, who completed assessments on parental attachment bonds (using the Parental Bonding Instrument), differentiation of self (using the Differentiation of Self Inventory Revised), and couple functioning (using the Dyadic Adjustment Scale). Structural Equation Modeling analyses revealed that the quality of parental attachment predicted distinct patterns of differentiation of self, which subsequently accounted for significant variability in dyadic adjustment levels. The implications of our findings are discussed.
A ″On–Off″ Fluorescent Sensor Based on Coumarin-Furoic Hydrazide for Recognition of Fe3+: Drinking Water, Test Strip Applications and DFT Calculations
Authors: Karagoz Abdurrahman , Savran Tahir , Yilmaz Ibrahim 
Published: February 2025

Abstract
A coumarin based fluorescent probe (E)-N'-((7-hydroxy-2-oxo-2H-chromon-3-yl)methylene)furan-2-carbohydrazide (CFHZ) was synthesized for the detection of Fe3+ and its characterizations were carried out using spectroscopic methods such as FT-IR, mass spectrometry1H-NMR, 13C-NMR. The novel probe CFHZ showed a highly selective and sensitive “turn-off” response to Fe3+ ion without any interference from other analytes. Strong fuorescence quenching phenomena of the CFHZ were observed in EtOH:H2O (99/1, v/v) detection system (λem = 470 nm) upon the additions of Fe3+. The binding stoichiometry between CFHZ and Fe3+ was determined by Job's method, FT-IR and MALDI TOF–MS and found to be 2:1. Also, the binding constant was determined to be 1.82 × 105 M−1 and the limits of detection for the analysis of Fe3+ was measured as 25.7 nM. Besides, experimental applications were carried out for real-time monitoring of Fe3+ in water samples using developed sensor. Additionally, fluorescence imaging experiments for Fe3+ detection of CFHZ probe on test papers were successfully performed.
Exploring the Intersection of Cancer, Domestic Homicide, and Domestic Abuse-Related Suicides Using Domestic Homicide Reviews
Authors: Dheensa Sandi , Bracewell Kelly , Boughton Grace , Hepworth Eleanor , Myall Michelle , Rowlands James 
Published: February 2025

Abstract

Purpose
Research about the overlap between cancer and domestic abuse (DA) is limited. We analyzed Domestic Homicide Review (DHR) reports from England and Wales where the victim or perpetrator had a cancer diagnosis to investigate the nature of DA in a cancer context, and cancer care and other healthcare professionals’ (HCPs) responses to DA.

Methods
We adopted the READ approach to document analysis: Readying materials (including manually searching reports for the term ‘cancer’); Extracting data; Analyzing data; and Distilling findings (using thematic analysis). We framed results using the social-ecological model of violence.

Results
We retrieved 24 DHR reports, which covered 27 domestic homicides/DA-related suicides. Victims had cancer diagnoses in 15/27 cases, perpetrators in 8/27, and both in 1/27. Three cases involved two homicides. Victims were mostly older (median 67). Most (19/24) domestic homicides/DA-related suicides occurred within 3 years of diagnosis, yet cancer HCPs rarely made explicit contributions to the DHR process. Our qualitative themes explain how: (1) cancer and DA affected each other; (2) professionals missed opportunities to identify and respond to DA (including because cancer masked DA indicators, turning down care and support offers were underrecognized indicators, and care was fragmented and non-holistic with insufficient information-exchange); and (3) cancer diagnoses were under-considered and misunderstood in the DHR process.

Conclusions
Since cancer masked DA indicators, professionals working with affected people and families should have a low threshold for concern. More explicit contributions to DHRs by cancer HCPs may improve understanding of this intersection and improve future practice.
Uncertainty and Well-Being in Turkish Adults: Exploring the Role of Religiosity and Psychological Symptoms
Authors: Türk Nuri , Arslan Gökmen , Kaya Alican , Yildirim Oğuzhan 
Published: February 2025

Abstract
Religiosity offers individuals a sense of purpose and connection, which can lead to greater life satisfaction and improved psychological well-being and happiness. On the other hand, psychological challenges such as depression, anxiety, stress, and difficulty dealing with uncertainty can negatively affect life satisfaction. This study examined these dynamics using a hypothetical model, incorporating mediation and moderation analyses to explore the connections between intolerance of uncertainty, life satisfaction, religiosity, and psychological symptoms in a group of 565 participants (286 of whom were female). The findings revealed notable positive and negative relationships among these variables. Specifically, the study found that (i) religiosity and psychological symptoms both play a mediating role in the link between intolerance of uncertainty and life satisfaction, and (ii) religiosity serves as a moderator in this relationship. The moderation analysis showed that when religiosity levels are low, the negative effect of intolerance of uncertainty on life satisfaction is significantly stronger. In contrast, high levels of religiosity significantly weaken this negative relationship, indicating that religiosity acts as a buffer against the adverse impact of uncertainty on life satisfaction. These results underscore the potential value of religiosity in helping individuals cope with the harmful effects of uncertainty on their sense of life satisfaction. Additionally, lower levels of psychological symptoms and reduced intolerance of uncertainty were associated with higher life satisfaction, suggesting that religiosity may play a protective role in promoting overall well-being.
Strong nonreciprocity in a bistable pendulum with contactless coupling to a monostable pendulum
Authors: Rouleau Michael , Booker Zachary , Shi Chengzhi , Meaud Julien 
Published: February 2025

Abstract
This article studies the nonreciprocity of a system that consists of a bistable element coupled to a monostable element through a contactless magnetic interaction. To illustrate the concept, the bistable element is physically realized using a pendulum that interacts with a stationary magnet and the monostable element is a classical pendulum. A numerical model is implemented to simulate the nonlinear dynamics of the system. Both simulations and experiments show that the system exhibits a strong amplitude-dependent nonreciprocity in response to initial excitations. At small input amplitudes, the system has an intrawell response with minimal transmission of energy whether the excitation is exerted on the side of the bistable pendulum or on the other side. However, at high input amplitude, a strong nonreciprocal behavior is observed: excitation of the bistable pendulum causes an interwell response which considerably reduces the distance between the two pendulums and allows energy to be efficiently transmitted through the contactless magnetic interaction; excitation of the monostable pendulum does not cause any interwell response and results in limited energy transmission. The combination of bistability and contactless nonlinear interactions allows the system to exhibit very strong amplitude-dependent nonreciprocity, which may be useful in a wide range of applications.
Aleksandr Dugin’s Traditionalist roots
Authors: Sedgwick Mark 
Published: February 2025

Abstract
By the time of the Russo-Ukrainian War, the Russian political activist Aleksandr Dugin was known as an ultra-nationalist, a fascist, a geopolitician, a Eurasianist, a Heideggerian, and sometimes also as a Traditionalist in the school established by René Guénon. Some, however, hold that Dugin had left Traditionalism far behind, or perhaps had never really been a Traditionalist in the first place. This article examines the extent to which Dugin’s engagement with Traditionalism has persisted throughout his intellectual and political career. It begins with Dugin’s formative years in the late-Soviet Iuzhinskii Circle, where he first encountered Traditionalism, and explores his adaptations of Guénon’s views. The article argues that Dugin’s works, including his best-seller The Fundamentals of Geopolitics (1997), reflect his continued commitment to Traditionalist principles, despite significant modifications. The article thus challenges views that dismiss Dugin’s Traditionalism as superficial or abandoned. It concludes that Dugin’s enduring adherence to Traditionalism is essential to understanding his influence on Russian political thought and his broad appeal.
Classic Theory of Aerosol Filtration for Application to Urban Green Infrastructure
Authors: Tomson Nathalie , Michael Ruby N. , Agranovski Igor E. 
Published: February 2025

Abstract
The use of green infrastructure (GI) in urban environments has been widely investigated for its associated ecosystem services including air pollution mitigation. Plants are well-known for their ability of purifying air through photosynthesis and microbial activities occurring in the rhizosphere, however the simple filtration of particulate matter in air by plants is still not well understood. This study aimed to investigate the potential to adapt classic filtration theory for application in GI design. Two native Australian plants used as filter media were involved in laboratory experiments to remove aerosol particles ranging in size from 0.3 to > 10 µm. A comparison of aerosol removal efficiencies obtained from the laboratory experiments and predicted through classic filtration theory showed good correlation for the smaller (needle-like) leaf system. In contrast, the correlation obtained for a plant with larger elliptical leaves was not as good, showing a larger difference between the results. Such outcomes led to the conclusion that smaller and spatially homogeneous plant systems have more predictable aerosol filtration characteristics, which can be reasonably calculated using filtration theory. This finding provides practical insight into GI design, allowing quantitative predictions of local air pollution reductions using green barriers.

Graphical Abstract
Resistance exercise training in older men reduces ATF4-activated and senescence-associated mRNAs in skeletal muscle
Authors: Von Ruff Zachary D. , Miller Matthew J. , Moro Tatiana , Reidy Paul T. , Ebert Scott M. , Volpi Elena , Adams Christopher M. , Rasmussen Blake B. 
Published: February 2025

Abstract
Sarcopenia increases the risk of frailty, morbidity, and mortality in older adults. Resistance exercise training improves muscle size and function; however, the response to exercise training is variable in older adults. The objective of our study was to determine both the age-independent and age-dependent changes to the transcriptome following progressive resistance exercise training. Skeletal muscle biopsies were obtained before and after 12 weeks of resistance exercise training in 8 young (24 ± 3.3 years) and 10 older (72 ± 4.9 years) men. RNA was extracted from each biopsy and prepared for analysis via RNA sequencing. We performed differential mRNA expression, gene ontology, and gene set enrichment analyses. We report that when comparing post-training vs pre-training 226 mRNAs and 959 mRNAs were differentially expressed in the skeletal muscle of young and older men, respectively. Additionally, 94 mRNAs increased, and 17 mRNAs decreased in both young and old, indicating limited overlap in response to resistance exercise training. Furthermore, the differential gene expression was larger in older skeletal muscle. Finally, we report three novel findings: 1) resistance exercise training decreased the abundance of ATF4-activated and senescence-associated skeletal muscle mRNAs in older men; 2) resistance exercise-induced increases in lean mass correlate with increased mRNAs encoding mitochondrial proteins; and 3) increases in muscle strength following resistance exercise positively correlate with increased mRNAs involved in translation, rRNA processing, and polyamine metabolism. We conclude that resistance exercise training elicits a differential gene expression response in young and old skeletal muscle, including reduced ATF-4 activated and senescence-associated gene expression.
Association between gene mutations and outcomes in Japanese high-risk AML patients: a phase 1/2 study of NS-87/CPX-351
Authors: Makishima Hideki , Mikasa Taisuke , Isogaya Kento , Miyamoto Toshihiro , Yamauchi Takuji , Yokota Akira , Onozawa Masahiro , Ando Kiyoshi , Ogawa Yoshiaki , Usuki Kensuke , Yamauchi Takahiro , Ota Shuichi , Takada Satoru , Morita Yasuyoshi , Ishikawa Takayuki , Takenaka Katsuto , Kuroda Junya , Sekiguchi Naohiro , Kawakita Toshiro , Miyazaki Yasushi 
Published: February 2025

Abstract
This phase 1/2 study investigated the association between genetic characteristics and outcomes for NS-87/CPX-351 in Japanese patients with high-risk acute myeloid leukemia. Blood samples collected from 29 patients were analyzed using a 70-gene next-generation sequencing panel. The most frequently mutated genes were TP53 (44.8%), TET2 (24.1%), DNMT3A (13.8%), and NRAS (13.8%). The rates of composite complete remission (CRc; complete remission [CR] or CR with incomplete hematologic recovery [CRi]) were comparable between patients with and without mutations in TP53, TET2, DNMT3A, and NRAS (P = 0.571 for all). Notably, patients with TP53 mutations had a similar CRc rate (69.2% vs. 56.3%), but shorter overall survival (OS), event-free survival (EFS), and relapse-free survival (RFS) compared to patients with wild-type TP53 (median OS: 7.43 vs. 18.18 months; P = 0.108, median EFS: 2.43 vs. 6.28 months; P = 0.012, median RFS: 1.48 vs. 10.19 months; P = 0.012). In conclusion, no gene mutations directly associated with the efficacy of NS-87/CPX-351 were found. While NS-87/CPX-351 achieved remission even in patients with TP53 mutations, relapse risk was higher in these patients. Therefore, it is advisable to consider treatment strategies such as early transplantation after achieving remission with NS-87/CPX-351, especially in patients with TP53 mutations.