bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Influence Interest in Entrepreneurship Semarang State Polytechnic Student
Authors: Setyawan Nanang Adie , Wibowo Bagus Yunianto 
Published: June 2024

This study aims to determine the factors that influence interest in entrepreneurship which consists of entrepreneurial mindset, environment and the influence of social media on Semarang State Polytechnic students. Respondents in this study were students of Semarang State Polytechnic with a sample of 100 respondents from the entire population. This study uses a confirmatory factor analysis tool in the SEM of the AMOS 24.0 statistical package. The data collection technique used a questionnaire with incidental sampling and snow ball sampling, namely students who were met and had run entrepreneurship or had participated in entrepreneurship studies and forwarded it to their friends according to the criteria. The results of parameter estimation are consistent with the hypothesis that entrepreneurial mindset significantly influences entrepreneurial interest with a critical ratio (c.r) value of 3.194 and a P-Value of 0.001, Environment has a positive effect on entrepreneurial interest with a critical ratio value (c.r) of 3.179 and a P-Value of 0.001, Social The media has a positive effect on entrepreneurial interest with a critical ratio (c.r) of 4.366 and P-Value ***. The results of this study indicate a positive and significant influence between entrepreneurial mindset, environment, and social media on students' interest in entrepreneurship.Â Kata Kunci: Minat Berwirausaha, Media Sosial, Pola Pikir Wirausaha, Lingkungan.
Design and Efficiency of a String Hulling Machine for Buckwheat
Authors: Samoichuk Kyrylo , Fuchadzhy Natalia , Kovalyov Alexandr , Hutsol Taras , Horetska Iryna , Semenyshena Ruslana , Yermakov Serhii , Rozkosz Anna 
Published: June 2024

Abstract
An important task of food engineering, namely grain processing and the pro-duction of cereals and fodder, is the improvement of hulling equipment and the creation of complex technological lines for the processing of the original crops is gaining particular relevance. The reason for this is the need to carry out several preparatory stages, and, as a result, the use of additional equipment. To solve this problem, a string hulling device had been developed, the use of which allows reducing the number of operations due to the exclusion of preliminary sorting into fractions and wet-heat treatment. These operations are required by other hulling machines included in the technological lines of buckwheat processing. The structural scheme of the string hulling device had been developed and the principle of the shell removal operation had been substantiated. Theoretical studies had been carried out by the methods of analysis and synthesis of the mechanics of destruction and systematic analysis of the process of buckwheat hulling by impact. Experimental studies had been carried out using a laboratory string hulling device. The conducted analytical studies made it possible to determine the regularity between the physical and mechanical characteristics of buckwheat and the critical linear impact speed necessary for the destruction of the shell. This allows deter-mining the frequency of rotation of the string at which the destruction of the shell will occur while preserving the integrity of the core. Experimental studies made it possible to determine the quality of buckwheat hulling by determining the coefficient of integrity of the kernel and the coefficient of hulling. It has been determined that the ranges of the rotation frequency of the strings required to ensure a high degree of the buckwheat hulling technological process efficiency are within 15.8-16.9 s−1.
Multi-Objective Optimization of the Green Extraction Conditions of Bio-Active Compounds from a Levisticum officinale WDJ Koch: Pareto Optimality and Compromise Solutions for Process Management
Authors: Plawgo Michał , Kocira Sławomir , Bohata Andrea 
Published: June 2024

Abstract
Plants belonging to the Apiaceae family (including Levisticum officinale WDJ Koch) are rich sources of phytochemicals and secondary metabolites, with possible health-promoting and agrochemical potential. The objective of this work was to provide important guidelines for controlling conventional aqueous extraction to obtain Levisticum officinale root extracts with maximised levels of bioactive compounds. The ultimate goal was to optimise the total phenolic compounds, flavonoid content, sugars, and total antioxidant capacity to identify the process conditions necessary to produce highly bioactive extracts that could be used in a wide range of industries. Biomass extraction of lovage root was carried out using water as the extraction solvent. To perform the optimisation of the aqueous extraction, multivariate regression models were used and multi-criteria analysis was performed using Pareto set navigation. Pareto front analysis showed that for the maximum extraction efficiency of bioactive compounds from Levisticum officinale, the optimal extraction process parameters were 0.0714 g·mL−1 as biomass/water ratio and a time of 35.7142 min, at the highest analysed temperature. For the highest analysed value of plant biomass/solvent ratio (0.075 g·mL−1) and maximum process temperature (95ºC), extraction could be carried out for 20 min or in the range 37.1429-38.5714 min. On the other hand, if the extraction time reaches 40 min and the sam-ple/solvent ratio 0.075 g·mL−1, the optimum process temperature is be-tween 75ºC and 95ºC.
Therapeutic importance, general and endocrine adverse effects of immune checkpoint inhibitors I: mechanism of action and therapeutic use
Authors: Kun Imre Zoltán , Kun Ildikó , Hadnagy Margit , Kolcsár Melinda 
Published: June 2024

Abstract
The tumor microenvironment has a fundamental role in the escape phenomenon of cancerous cells from the immune surveillance, the immunological protective mechanisms of the host. These cells produce active substances that can bind to and stimulate the inhibitory immune checkpoints (CTLA-4, PD1 etc.) expressed on the cytotoxic T-lymphocytes and other immunocompetenT-cells, thus inhibiting the immune defense. The immune checkpoint inhibitors (ICIs), introduced in therapeutic use in 2011, are human or humanized monoclonal antibodies (mAbs) that block the immune checkpoints, and thus release the inhibition, restoring the antitumoral immune defense. After the description of their mechanism of action, the clinical applications of anti-CTLA-4 mAbs ipilimumab and tremelimumab, anti-PD1-antibodies nivolumab and pembrolizumab, and the anti-PD-L1-antibodies are presented. The ICIs are used mainly in inoperable and advanced tumors, but this fact is not a rigorous rule, and their therapeutic indications have been and will continue to expand. The next section summarizes new research directions that are also needed, because primary and adaptive resistance to ICIs exists, the latter developing during therapy. In an unselected population, ICIs are therapeutically efficient only in about 20-30% of patients, but these will be long-term survivors. Not rarely the therapeutic effect is preceded by a transient pseudoprogression. Tumors with high mutation burden (melanoma, lung, and bladder cancers) respond much better to ICI therapy, because they produce more neoantigens; this is the case in the “hot” tumors, too, because in these tumor-infiltrating immune cells are markedly present. Their application would require reliable predictive biomarkers, but there are few of them so far, e.g., investigation of PD-L1 expression, and diagnostic tests associated to ICIs. This first part of the review ends with problems regarding therapy resistance and their possible solutions.
Theological Affinities Between the Fourth Gospel and the Book of Revelation
Authors: Köstenberger Andreas J. 
Published: June 2024

Abstract
The focus of this study is on the exploration of theological affinities between the Fourth Gospel and Revelation. While I personally hold to the apostolic authorship of both writings by John, the son of Zebedee — admittedly a minority view in contemporary Johannine scholarship—the specific identity of the author will not be of primary concern here. Rather, my focus will be on the plausibility (or lack thereof) of common authorship, whether by the apostle or another writer. If it can be shown that the differences in outlook between the Fourth Gospel and Revelation may be accounted for by different subject matter, genres, and circumstances addressed, an important objection against the common authorship of the two documents will be removed.
Treatment-Refractory Eosinophilic Esophagitis Successfully Managed with benralizumab: A Case Presentation and literature review
Authors: Petrousis Grigorios , Retsas Pavlos , Ignatova Simone , Karapiperis Dimitrios 
Published: June 2024

Abstract
Eosinophilic Esophagitis is a widely-recognized immune-mediated esophagus disease with distinct clinical and histopathological features, exhibiting an increased global incidence. Therapeutic options encompass either dietary measures or pharmacological approaches, including proton pump inhibitors and topical corticosteroids. The use of monoclonal antibodies is currently under comprehensive evaluation, with a plethora of ongoing clinical trials designed to determine their clinical efficacy. The present case report demonstrates an exceptional case of refractory Eosinophilic Esophagitis, unresponsive to conventional treatment, achieving both clinical and histopathological remission subsequent to initiation of benralizumab treatment. Concurrently, our case underscores the necessity for continued research in the field of monoclonal antibodies for their use as a future treatment approach against Eosinophilic Esophagitis.
Designing a Theme-Based Lesson to Develop Creativity Competency for Primary Students
Authors: Hang Ngo Vu Thu 
Published: June 2024

Creativity is an important competency that needs to be formed and developed for primary school students. This competency can be educated to students through appropriately designed theme-based lessons. This paper provides some theoretical issues about theme-based lessons and creativity competency, builds a model that shows the characteristics and structure of a theme-based lesson. The paper also shows a process for designing theme-based lessons to help develop creativity competency for primary school students. It provides a possible example of a theme-based lesson designed with the application of the above process that primary school teachers can learn and apply in classroom practices, helping to develop creativity competency for primary students, contributing to the successful implementation of the General Education Program 2018.
Application EON-XR Virtual Reality Technology in the Design of Biology Learning 10th Grade
Authors: Thi Thuy Quynh Nguyen , Luong Kim Thi 
Published: June 2024

With the specific characteristics of Biology subject, it is necessary to have more images illustrating the biological structures that make up the living world, or super-microscopic structures that humans cannot observe with the naked eye such as prokaryotes, eukaryotic cells or microorganisms. Through the outstanding feature of 3D image simulation, EON-XR is an effective support tool in teaching biological structures and processes. Learners can approach Biology knowledge in a more vivid way, easily visualize and have accurate concepts about images, things and phenomena when interacting with them like in the real environment. A 4-steps process was developed when designing a teaching plan that applies virtual reality technology. Some products have been designed using EON-XR virtual reality technology. These products are related to Cell Biology, Biology grade 10th section such as: biomolecules, structure of cells, prokaryotic and eukaryotic cells. Pedagogical experiments have shown that the application of EON-XR helps students deepen their understanding of knowledge and increase interest in the subject. The information technology capacity of students in the experimental class (classes with VR application) was evaluated and higher than that of students in the control class (taught by traditional methods). The results of this study have proved the effectiveness of designing teaching activities with VR applications to improve the quality of teaching Biology in high schools to meet current educational innovation requirements.
Code-switching in Kurdish communication "Khanaqin Dialect as an Example "
Authors: Rashid Salam Raheem , Hama Ameen Khoshnaw Azeez , Muhamed Sozan Kareem 
Published: June 2024

In linguistics, especially in communication, code-switching, or skipping from one linguistic code (dialect or a language) to another, as a reference to the use of several languages or several dialects together, usually occurs in multilingualism groups that the speaker uses the elements of multiple diverse languages. This process is related to a number of factors, principles and specific circumstances. Khanaqin City is one of these areas where this phenomenon is witnessed and worth studying, this by taking its geographical location and political situation into consideration, and their influences on this linguistics phenomenon.
Consequently, this study which is entitled Code-switching in Kurdish communication "Khanaqin Dialect as an Example‌‌", is devoted and intended to demonstrate that in linguistic sphere, it is possible to deal with the phenomenon through speech analysis. i.e., it is attempted that the code-switched linguistic forms of this area to be discussed and studied depending on linguistics criteria.
In order to achieve the objectives, descriptive analysis method has been applied in this paper. The structure of the paper in spite of the preface and an introduction of the subject is outlined into two parts as follows:
The first part is the theoretical aspect of the research, in a brief introduction of Khanaqin and the use of language there have been presented. The second part is the practical aspect of the study, which adresses the phenomenon of code switching, its principles and types within the scope of the research. It has been strived to elaborate the topics in the form of analysis and providing examples.
The results obtained, the list of bibliography, in addition to this summary in Arabic and English languages conclude this effort.
An Eco-Traumatic Iraqi Experience in Sinan Antoon's The Corpse Washer: An Eco-Critical Perspective
Authors: Jassim Shaima Abdullah , Mohammed Sarmad Majeed 
Published: June 2024

From the ancient time up to now, the concept of place and its shadow in literary milieu are not passive. This mutual interconnectedness between literature and place considers a complex relationship that weaves many notions within its context.
However, in this present paper, the researchers focus on one of the most well-known Iraqi novel which is The Corpse Washer (2013), written by Sinan Antoon (1967-present). Through this novel, the researchers negotiate the traumatic experience of Iraqi people that stems from the trauma of place and its impact on the relationship between human being and environment where they live. By adapting Eco-trauma theory, which is set by Tina Amorok, the researchers conclude that the novelist creates a microcosm to examine the nature of relationship between human being and environment. Based on this fact, they find that Antoon has portrayed the relationship between environment and Iraqi individuals as unsettled relationship due to the traumatic experience that place causes upon Iraqi people. Thus, Antoon's symbolic depiction of the protagonist as a rebellious character comes from the influence of environment upon human beings which formulates their attitudes and understanding. This is clearly depicted by the protagonist Jawed, who always tries to break his relationship with the environment for the sake of achieving his dreams and be an independent man.
Research on the multi-scenario control strategy of an active distribution network based on Rotary Power Flow controller
Authors: Mingming Shi , Jun Ma , Xiaolong Xiao , Fan Wu 
Published: June 2024

Aiming at the problems of complex power distribution and difficult adjustment in the active power distribution network, a low-cost, harmonic-free, and low-loss electromagnetic Rotating Power Flow Controller (RPFC) scheme is proposed. First, the topology, working principle, and equivalent circuit of RPFC are introduced, the steady-state characteristics of RPFC are studied, and a steady-state voltage source model containing RPFC lines is established. On this basis, in order to solve problems such as voltage over the limit, phase angle difference, line flexible closed-loop closing, and power control in the active distribution network, an RPFC rotor angle solution strategy based on the improved Multi-Scenario Adaptive Genetic Algorithm (MAGA) was proposed. Taking the actual network as a case, a specific algorithm model was established based on Matlab/Simulink, and compared with the RPFC system under traditional PI control. The results show that using MAGA as the control algorithm enables RPFC to have better performance in voltage regulation and power flow control scenarios. In the voltage regulation scenario, MAGA-RPFC saves 1.5 s of regulation time compared with traditional PI-RPFC. In the power control scenario, the adjustment time is saved by 18.2 s. At the same time, the simulation results show that RPFC can effectively solve the voltage regulation, flexible closed-loop, and power regulation problems in active distribution networks, and has broad application prospects.
Metallosis After Total Hip Arthroplasty
Authors: Flatt Sarah , Rawat Mohini 
Published: June 2024

A 67-year-old overweight woman was referred to physical therapy by an orthopaedic surgeon for lumbosacral spondylosis without myelopathy. Past medical history included a right total hip arthroplasty (THA) 9 years ago and a left THA 7 years ago. The patient underwent a 6-week physical therapy program but did not improve as expected, which resulted in a consultation with another in-house physical therapist who performed musculoskeletal ultrasound of the right hip, revealing a soft tissue mass. The patient was referred back to the orthopaedist, who ordered magnetic resonance imaging that confirmed an oval mass along the lateral right hip. Further testing was positive for cobalt poisoning, and the patient was diagnosed with metallosis. JOSPT Cases 2021;1(3):197–198. doi:10.2519/josptcases.2021.10339
Manometric profile of patients presented with dysphagia – A hospital-based descriptive study
Authors: Yogisparan Pavitra Vyshnavi , Arun P. , Vijayabaskaran S. , Sairam Vidhya , Deepalakshmi K. , Mukundan S. , Thirumal P. , Vasanthi R. , Venkatakrishnan L. 
Published: June 2024

Objectives:
The prevalence of dysphagia is 16–22%. Achalasia is characterised by impaired relaxation of the lower oesophageal sphincter (LES) and absent oesophageal peristalsis. Minimally invasive procedures, endoscopic pneumatic balloon dilatation (PD) and peroral endoscopic myotomy (POEM) are treatments of choice. We aimed to assess the manometric profile of patients presented with dysphagia and pre- and post-LES pressure and integrated relaxation pressure (IRP) of patients who underwent PD and POEM.

Materials and Methods:
One hundred and twenty-nine patients presented with dysphagia underwent high resolution oesophageal manometry (HREM). Manometric parameters: IRP, LES and pattern of motility were noted. According to Chicago classification 4.0, those who are diagnosed with achalasia underwent PD (17) and POEM (15). Statistical analysis was performed using the Statistical Package for the Social Sciences version 28. Pre- and post-procedure values (IRP and basal LES) were compared using the Wilcoxon signed-rank test.

Results:
Out of 129 patients with dysphagia, 57 had increased IRP and 75 had simultaneous motility. The mean LES pressure and IRP were found to be 28 ± 19.82 and 17 ± 14.04 mmHg, respectively. On analysis, of patients who underwent procedures PD (17) and POEM (15), a statistically significant decrease in IRP was observed in patients with post POEM compared to post PD status (P = 0.005 and 0.017, respectively). Reduced basal LES pressure was observed in patients with post-POEM status compared to post-PD status, which was not statistically significant.

Conclusion:
About 44% of patients presented with dysphagia were diagnosed with achalasia cardia. POEM procedure was found to be more effective compared to pneumatic dilatation.
Model Klasifikasi Kesesuaian Lahan Bawang Putih Menggunakan Interpolasi Spasial dan Algoritme Pohon Keputusan
Authors: Dini Hayati  , Imas Sukaesih Sitanggang  , Annisa  
Published: June 2024

Bawang putih merupakan salah satu hasil hortikultura yang harus terpenuhi setiap tahunnya. Jumlah produksi bawang putih tidak sebanding dengan jumlah konsumsi bawang putih menjadi acuan pemerintah untuk melakukan impor guna mencukupi kebutuhan dalam negeri. Hal ini menjadi dasar pemerintah untuk melakukan swasembada bawang putih. Usaha yang dilakukan untuk mencapai swasembada bawang putih salah satunya adalah melakukan perluasan lahan untuk tanaman bawang putih. Penelitian ini bertujuan untuk menentukan model klasifikasi kesesuaian lahan bawang putih menggunakan algoritme C5.0 berdasarkan karakteristik lahan dan interpolasi temperatur menggunakan metode Inverse Distance Weighted (IDW). Penelitian ini menghasilkan pohon keputusan dengan 5 aturan kelas kesesuaian lahan dengan akurasi sebesar 97.81% pada dataset dengan data temperatur bulan Mei 2022. Variabel penting dalam menentukan kelas kesesuaian lahan pada periode ini adalah kedalaman mineral tanah. Sedangkan nilai akurasi pada dataset dengan data temperatur bulan Juli 2022 menghasilkan model pohon keputusan dengan 17 aturan kelas kesesuaian lahan dengan akurasi sebesar 95.91%. Variabel penting dalam menentukan kelas kesesuaian lahan pada periode ini adalah kejenuhan basa.
Kajian Kondisi Stok Ikan Layang (Decapterus macrosoma ) di perairan Laut Banda Utara, Maluku
Authors: Soukotta Imanuel V.T , Supusepa Junita , Moniharapon Domey L 
Published: June 2024

Abstrak:
Ikan layang putih adalah sumberdaya perikanan pelagis kecil yang potensial di perairan teritorial Indonesia dan berada di Provinsi Maluku, khususnya di perairan Banda Utara. Penelitian ini dilakukan di perairan Banda Utara, Maluku, dari bulan Januari 2024 sampai April 2024. Tujuan penelitian ini adalah mempelajari kondisi stok ikan layang putih (D. macrosoma) didasarkan pada dinamika populasi dari distribusi kelompok ukuran ikan (kohort) , ukuran ikan pertama kali tertangkap (Lc), pola pertumbuhan dan ukuran pertama matang gonad. Contoh ikan dikoleksi tiap bulan di tempat pendaratan dari nelayan purse seine. Total 510 individu. Kondisi stok ikan layang putih didasarkan pada analisis menunjukkan bahwa stok masih di bawah tingkat Kohort bulan Ferbuari tertinggi pada 27,30-28,80 cm , ikan layang yang pertama kali tertangkap (Lc) 50% adalah 23,2 cm , panjang asimptot (L∞) sebesar 33,2 cm dan nilai koefisien laju pertumbuhan (K) sebesar 0,08 per tahun dan ukuran ikan layang pertama kali matang gonad (Lm 50) adalah 22,08 cm. Agar tetap menjaga keberadaan stok ikan layang tersebut diharapkan agar penangkapan dengan menggunakan jaring bobo (purse saine ) harus selektif.