bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kaviraj Jamini Bhusan Roy: The man who led the Ayurveda renaissance in Bengal
Authors: Bhushan Shakti , Saha Suparna , Panja Asit 
Published: May 2024

Abstract
Kaviraj Jamini Bhusan Roy is an eminent Ayurveda scholar and philanthropist from Bengal. Roy demonstrated academic excellence, graduating high school at 14 years of age. Despite earning a gold medal in Western medicine in 1905, he embraced Ayurveda, establishing a successful practice in Kolkata. His significant contributions include prolific writings on Ayurveda and the establishment of the Ashtanga Ayurveda College and Hospital in 1916 at Kolkata, presently known as J. B. Roy State Ayurvedic Medical College & Hospital, one of the earliest institutions of Ayurveda in Bengal. Roy played a crucial role in modernizing the manufacturing of Ayurveda medicines by adopting standardized manufacturing practices. His indomitable spirit and passion for philanthropy are evident in setting up medical care dispensaries across the state and institutions such as J. B. Roy State Ayurvedic Medical College & Hospital. The study is an attempt to meticulously document his life and accomplishments, marking his contribution to the history of contemporary Ayurveda.
Intracanal medicaments and coronal sealing materials influence on root fracture resistance and coronal discoloration: An in vitro study
Authors: Sahebalam Rasoul , Boskabady Marzie , Naghavi Maryam , Dehghanitafti Samira 
Published: May 2024

Abstract

Introduction:
Immature teeth are more susceptible to fracture, and intracanal medicaments and coronal filling materials used in regenerative endodontics affect their optic and mechanical properties. This study aimed to evaluate the fracture resistance and coronal discoloration of simulated immature teeth following the placement of several intracanal medicaments and coronal sealing materials.

Materials and Methods:
Eighty-eight premolars simulating immature teeth were divided into 11 groups (n = 8 each) according to the type of intracanal medicament (triple antibiotic paste [TAP]; double antibiotic pastes [DAP]; calcium hydroxide [Ca(OH)2]) and used coronal barrier materials (mineral trioxide aggregate [MTA] and calcium-enriched mixture [CEM]). A bonding agent was applied in half of the samples in the groups where antibiotic pastes were used (n = 8). After incubating for 3 weeks, the sample’s fracture resistance and color change were evaluated. Data analysis was conducted using multivariate and one-way analysis of variance, Tukey’s honestly significant difference post hoc, and the Kruskal–Wallis tests (α =0.05).

Results:
The color change after placing the medicaments was comparable among the groups. However, after 3 months, the color change in the TAP-CEM-No-Bonding group was higher than the control, Ca(OH)2-MTA, and DAP-MTA-No-Bonding groups (P < 0.05). The fracture resistance of the TAP-MTA-Bonding, DAP-CEM-Bonding, Ca(OH)2-MTA, and Ca(OH)2-CEM was lower than the control group (P < 0.05).

Conclusion:
Simultaneous use of DAP-MTA without a dentin bonding agent led to comparable color change and fracture resistance to the control group.
Preparation of 2D Tungsten Diselenide (WSe2) thin films by selenization of DC-sputtered W precursors
Authors: Mwakyusa Lwitiko P. 
Published: May 2024

Two-dimensional layered transition metal dichalcogenides based on WSe2 films demonstrated promising properties for nano-electronics and photovoltaic applications. In this work, WSe2 films were prepared by selenization of DC-sputtered W precursors. The influence of the selenization temperature on the structural, morphology, and optical properties of the WSe2 films was investigated. The selenization temperature was varied from 350 °C to 450 °C at the interval of 50 °C. Structural, morphology and optical properties of the WSe2 were investigated using X-ray diffractometry (XRD), Atomic Force Microscope (AFM), and UV-VIS-NIR spectrophotometer, respectively. XRD analysis revealed that all WSe2 were polycrystalline and exhibited the co-existence of c-axis perpendicular and parallel substrate texture. Samples selenized at 400 °C demonstrated strong - types of crystal orientations – perpendicular c-axis substrate texture – dominated crystal growth. The AFM images further revealed the co-existence of parallel and perpendicular crystal orientations for samples selenized at 350 °C and 450 °C. Optical measurement showed that all WSe2 samples were transparent and consisted of an excitonic peak at the wavelength of around 620 nm. The estimated bandgap values were in the range of 1.22 eV to 1.37 eV which is somchat lower than expected – the presence of W5O14 phases is suggested to be the main cause.
TEST OF RESISTANCE OF ALPUKAT (Persea americana mill) FRUIT EXTRACT ON THE GROWTH OF THE Streptococcus mutans
Authors: Rusmiany Putu , Nurdeviyanti Ni Nyoman , Yudistian Ilma , Lorenza Agnesia 
Published: May 2024

Introduction: Streptococcus mutans is one of the normal flora living in the oral cavity, but in excessive amounts is the main causative agent of dental caries. The active compounds of alkaloids, saponins and quinones in avocado pulp extract is an antibacterial alternative that can inhibit the growth of Streptococcus mutans in the oral cavity. The aim of this research was to determine the inhibitory power that contain in avocado pulp against Streptococcus mutans .
Materials and Methods: This study used 4 concentrations namely 25%, 50%, 75% and 100% with each repetition 4 times. Avocado pulp extraction was carried out by maceration method using 96% ethanol solvent. Inhibition zone testing was carried out using the Kirby baurer method.
Results and Discussions: The zone of inhibition was determined using the Kruskal wallis test, which showed that there were significant differences in various concentrations against the growth of Streptococcus mutans bacteria. Avocado fruit pulp extract is able to inhibit the growth of Streptococcus mutans bacteria because avocado fruit pulp extract has active compounds that cause antibacterial activity. Active compounds of avocado fruit flesh that are efficacious as antibacterials are alkaloids, saponins and quinones.
Conclusion: Avocado pulp extract has been proven to have an antibacterial effect against Streptococcus mutans with an effective concentration level of 100%. Increasing the concentration of avocado pulp extract was also shown to affect the diameter of Streptococcus mutans inhibition zone
CARACTERIZAÇÃO FÍSICO-QUÍMICA DOS FRUTOS DO UMBUZEIRO (Spondias tuberosa) PROVENIENTES DA CIDADE DE CAMPO REDONDO- RN
Authors: Morais da Rocha João Paulo , Augusto de Souza Pahlevi , Januário da Silva Raquel , Lopes da Costa Beatriz , Kelly da Silva Lucas Greyce , Clair Lira Santos Saint 
Published: May 2024

A qualidade dos frutos é atribuída aos seus caracteres físicos e sua composição físico-química. É essa qualidade intrínseca que oferece aos frutos e aos produtos deles obtidos a qualidade organoléptica e nutricional, responsável pela sua aceitação definitiva no mercado. Objetivou-se no trabalho analisar a qualidade físico-química do umbu (Spondias tuberosa) colhidos em diferentes estágios de maturação. Os frutos foram transportados até o Instituto Federal de Educação Ciência e Tecnologia do Rio Grande do Norte, campus Currais Novos, sanitizados com 200 ppm de cloro ativo para a limpeza superficial deles e classificados visualmente em: estágio 1 (verde), estágio 2 (esbranquiçado), estágio 3, 50% (amarelo) e estágio 4 (totalmente amarelo) considerando a coloração e firmeza da casca. Foram avaliados percentagem de casca, polpa e semente, diâmetro longitudinal e transversal, pH, acidez titulável, sólidos solúveis e ratio. Os frutos do estágio 1 apresentaram maior massa do fruto, maior quantidade de polpa e maiores diâmetros. Os frutos do estágio 4 (maduros) apresentaram maiores teores de sólidos solúveis, menor teores de acidez e maior rendimento de polpa, o que o caracterizam como adequados à comercialização.
Isolation and Characterization of Fibroblast from Normal and Thalassemia Foreskin
Authors: Widowati Wahyu , Faried Ahmad , Susanah Susi , Priyandoko Didik , Sugiaman Vinna Kurniawati , Nainggolan Ita Margaretha , Hafizha Nur Sabrina Adilah , Zahiroh Fadhilah Haifa , Hannan Nicholas Ray-Francis , Rizal Rizal , Wargasetia Teresa Liliana 
Published: May 2024

Thalassemia is a genetic blood disorder impacting hemoglobin production, varies in severity, and requires lifelong treatments. The advancement in somatic cell reprogramming through induced pluripotent stem cells (iPSCs) represents a personalized medicine approach that holds promise as a treatment for individuals with thalassemia. One source that could be reprogrammed into iPSCs can be generated from foreskin fibroblast cells. This study aimed to isolate and characterize human fibroblast cells from normal (NFF) and thalassemia (TFF) foreskin surface markers (CD44, CD90, CD105, CD73), and negative lineage (CD45, CD34, CD11b, CD19, HLA-DR). Fibroblast cells were isolated out of normal and thalassemia foreskin using the explant method. Characterization of NFF and TFF isolates was carried out using flow cytometry to disclose the expression of CD90, CD44, CD73, CD105, and negative lineage. Isolation of fibroblast cells from normal and thalassemia foreskin was successfully carried out using the explant method with NFF and TFF characterized as expressing CD90, CD44, CD105, CD73, and negative lineages (CD45, CD11b, CD34, CD19, and HLA-DR). This result could lead to a continuation of reprogramming into iPSCs.
HIGHLIGHTS

Isolation of fibroblast cells from normal and thalassemia foreskin was successfully carried out and cultured within 21 days
The surface marker (CD44, CD73, CD90, CD105), and negative lineage (CD45, CD34, CD11b, CD19, HLA-DR) showed similarity to MSCs
Fibroblast cells from the foreskin of normal and thalassemia patients were detected expressing CD90, CD105, CD73, CD44, and negative lineages (CD34, CD11b, CD45, CD19, HLA-DR)

GRAPHICAL ABSTRACT
The Role of Language Teaching in Promoting Educational Quality in Early Childhood Education
Authors: Wei Wen , Mamat Nordin Bin 
Published: May 2024

Background and purpose: China is among the countries putting great emphasis on strengthening early education programs to ensure a solid learning foundation for children. The present study is based on a qualitative research design to examine the role of English as a Foreign Language (EFL) teaching in promoting educational quality in the context of early childhood education in China. It focuses on investigating the effectiveness of EFL teaching in enhancing the educational quality of early childhood education in the education system of China. Method: The semi-structured interviews were conducted to assess the parents’ perception regarding the impact of EFL programs on the quality of education being offered in early childhood centres in China. The sample for the survey was selected from the parents of children enrolled in early childhood education centres in China offering EFL teaching as a part of their curricula. The data collection focused on the student’s cognitive development and overall quality of education. Findings: Most of the participants emphasized the significant impact of early EFL education on their children’s cognitive skills. They regarded EFL education as a robust tool to lay a strong foundation for future academic achievements and cross-cultural understanding of their children. Conclusion and Implications: Thus, parents in China regard early EFL education as crucial for the cognitive development and educational foundation of their children. The present study offers significant pedagogical implications regarding the inclusion of EFL instructions in enhancing the early language acquisition experience of children.
PENGGUNAAN APLIKASI KINEMASTER DALAM MENINGKATKAN MOTIVASI BELAJAR SISWA PADA PEMBELAJARAN AKIDAH AKHLAK DI MI NURUL ISLAM TANGERANG SELATAN
Authors: Masrurah Usmita Ainul , Anita Dewy 
Published: May 2024

Penelitian ini di latarbelakangi dengan beragamnya media pembelajaran yang digunakan untuk meningkatkan motivasi belajar siswa, salah satunya media tersebut adalah Kinemaster dengan penggunaan video yang lebih menarik. Tujuan dari penelitian ini adalah untuk mengetahui penggunaan aplikasi Kinemaster dalam meningkatkan motivasi belajar siswa dalam pembelajaran Akidah Akhlak pada siswa kelas II MI Nurul Islam Tangerang Selatan. Penelitian ini menggunakan metode deskriptif dengan pendekatan penelitian kualitatif. Fokus penelitian ini pada penggunaan aplikasi Kinemaster dalam meningkatkan motivasi belajar siswa pada pembelajaran Akidah Akhlak di MI Nurul Islam Tangerang Selatan. Hasil penelitian menunjukan bahwa penggunaan media pembelajaran aplikasi Kinemaster yang dilakukan oleh guru pelajaran Akidah Akhlak di MI Nurul Islam Tangerang Selatan dapat meningkatkan motivasi belajar siswa. Hal ini disebabkan karena Aplikasi Kinemaster dapat menggunakan bahasa yang mudah difahami oleh siswa, penyajian materi secara sistematis dengan menyesuaikan antara tema dan video, penggunaan aplikasi yang mudah serta penampilan dari videonya yang menarik disertai dengan gambar animasi yang disukai siswa sehingga siswa senang menonton videonya dan mengikuti pelajaran Akidah Akhlak di MI Nurul Islam Tangerang Selatan.
TRANSFORMASI PEMBELAJARAN BAHASA INDONESIA TINGKAT DASAR BERBASIS KURIKULUM MERDEKA
Authors: Maulida Utami , Tampati Riki 
Published: May 2024

Tulisan ini bertujuan untuk membahas secara komperehensif mengenai transformasi pembelajaran Bahasa Indonesia berbasis kurikulum merdeka di tingkat dasar. Kurikulum merdeka sudah hampir merata di tingkat satuan pendidikan terutama tingkat dasar yang termasuk fase A, sudah tentu teknik pembelajaran mengalami transformasi, salah satunya pembelajaran bahasa Indonesia. Pembelajaran Bahasa Indonesia yang tidak lagi stagnan dalam baca-tulis namun guru mengemas pembelajaran bahasa Indonesia lebih kreatif dan variatif. Metode penelitian ini menggunakan kualitatif dengan teknik content analysis, dimana peneliti menganalisis bagaimana pembelajaran Bahasa Indonesia ditransformasikan guru selama masa kurikulum merdeka. Hasil penelitian ini menunjukan bahwa guru Bahasa Indonesia telah melakukan transformasional dalam pembelajaran Bahasa Indonesia di tingkat dasar berupa memanfaatkan teknologi sebagai media pembelajaran, menggunakan metode dan strategi mengajar kekinian, serta menerapkan gerakan literasi sekolah melalui pembiasaan. Adapun nilai guna dalam penelitian ini sebagai gambaran mengenai transformasi pembelajaran Bahasa Indonesia berbasis kurikulum merdeka di tingkat dasar dan dapat dijadikan rujukan pembelajaran bagi pengajar lain khususnya sekolah yang baru menerapkan kurikulum merdeka.
PRÁTICAS DISCURSIVAS NO ENSINO DA LÍNGUA PORTUGUESA: O PAPEL DO DOCENTE
Authors: Souza Carolline da Conceição e 
Published: May 2024

Debate-se muito sobre a proficiência de alunos de ensino médio no que tange a habilidade de leitura e interpretação textual dentro das exigências estabelecidas nos parâmetros curriculares do novo ensino médio. Nesse intuito, esse artigo visa abordar as práticas discursivas no ensino de língua portuguesa, destacando o papel do docente nesse processo. Assim sendo, uma abordagem expositiva para a prática da leitura surge da necessidade de estabelecer novas estratégias de aprendizagem, para ampliar a capacidade de compreensão dos alunos nos mais variados tipos de texto, já que há a percepção da dificuldade dos alunos de realizarem uma leitura significativa e analítica, observando além dos elementos da estrutura do texto e os aspectos gramaticais, como os elementos extratextuais, inseridos no contexto. Dessa forma, buscou-se responder a seguinte questão: De que forma os gêneros discursivos permitem aprimorar a habilidade de leitura, diversificando o processo de ensino-aprendizagem da língua? Á vista disso, esta pesquisa está sendo proposta com o objetivo de trazer uma reflexão com relação às práticas discursivas no ensino de língua portuguesa, destacando o papel do docente nesse processo e com a aplicação dos gêneros discursivos, pretende-se analisar a situação expressa e os efeitos do sentido dos textos comunicativos. A metodologia utilizada foi pesquisa bibliográfica exploratória de especificidade descritiva, buscando evidenciar a percepção de que os gêneros discursivos permitem aprimorar a habilidade de leitura, diversificando o processo de ensino-aprendizagem da língua, pois os gêneros textuais, cada um com seu recurso estilístico, têm sua função social no desenvolvimento do aluno como leitor proficiente e crítico, transformando o ensino de língua portuguesa, e ainda estimulando tanto a prática do professor como a compreensão do aluno no processo de comunicação. A conclusão a que se chegou após o desenvolvimento dessa pesquisa é que a linguagem se estabelece na relação “escrita e fala”, por isso a necessidade do hábito da leitura, da produção textual, e a oralidade, utilizando os recursos linguísticos, tanto na forma escrita como na oral, permitindo uma prática de ensino mais complexa, e voltada para a formação do aluno quanto ao seu papel social, que envolve as atividades profissionais e o convívio familiar, portanto o educador deve sempre considerar o viés social do processo de ensino.
A EDUCAÇÃO MATEMÁTICA NA VIDA DO SER HUMANO
Authors: Tolentino Renê da Silva , Leal Debóra Aráujo 
Published: May 2024

O artigo discorre sobre as percepções da matemática na educação básica, na qual, busca-se compreender quais são as representações e vivências de alunos do Ensino Fundamental no início do aprendizado e que a importância social deste estudo é por compreender que matemática faz parte do contexto social, sendo indispensável nos diversos espaços sociais. Para encontrar soluções para o problema, o propósito desta pesquisa é compreender qual a funcionalidade e práticas que conduzem os alunos a perceberem a importância dessa disciplina e sua aplicabilidade e ter uma abordagem significativa, evidenciando nos resultados obtidos o entendimento dos alunos sobre a importância da matemática nos diversos espaços sociais de vivência e a essencialidade desta matéria na aprendizagem em todos os âmbitos educacionais. A metodologia é a pesquisa bibliográfica baseada em diversos autores que fortalecem a relevância do tema dentre eles: Berlinghoff e Gouvêa (2010), Ortiz (2005) Bessa (2014). Neste sentido será que as competências matemáticas desenvolvidas na escola são as mesmas exigidas no cotidiano dos alunos? A partir deste questionamento, é possível fazer uma reflexão sobre o ensino e aprendizagem da matemática e como ela deva ser aplicada para que esta, esteja de acordo com as transformações ocorridas em nossa sociedade. Diante do estudo realizado, concluiu-se que o uso da matemática, é primordial no processo didático pedagógico e em diversos momentos levando o educando a discutir, refletir e explicar conteúdos, oportunizando uma aprendizagem significativa.
OLHARES SOBRE A LINGUAGEM EM REDES SOCIAIS E SUAS INTERFACES COM A EDUCAÇÃO
Authors: Oliveira Glacileide de Andrade , Leal Debóra Aráujo 
Published: May 2024

Com o advento das tecnologias de informação e comunicação (TIC), a sociedade mudou a forma de comunicação, com o surgimento da internet, a sociedade mudou sua visão e postura em relação ao mundo. A diversidade de mecanismos disponibilizados com o acesso à internet tem influenciado a maneira como as pessoas estão se relacionando. Pouco a pouco os usuários tornam-se escravos dos aparelhos de dispositivos móveis, estabelecendo sua comunicação diária através do WhatsApp. Nesse contexto, a língua portuguesa não ficou imune das mudanças e adequações que atendam a velocidade do status online, em especial quando usadas pelos jovens, por serem usuários constantes e criativos que criam uma nova linguagem contaminada pelos emoticons. Partindo desse pressuposto, a presente pesquisa analisou a importância dessa comunicação eletrônica utilizada nas redes sociais como fator preponderante para a construção de uma nova linguagem. Os métodos e as técnicas para coleta de informações basearam-se na aplicação de formulários de observação a prints de 66 diálogos de 15 grupos de WhatsApp, amostra fornecida por 6 jovens de diferentes faixas etárias, cursando o Ensino Fundamental e Médio, vestibulandos em cursinho e universitários. Os formulários tiveram como objetivo contabilizar as ocorrências de emoticons durante conversas aleatórias, gerando gráficos para análise e alcançando os objetivos propostos pela pesquisa.
Optimization of Radiation Exposure when Examining Patients with Pathology of the Craniovertebral Region
Authors: Gukova A. D. , Petrovskaya V. V. , Lubashev Ya. A. 
Published: May 2024

The diagnostics are based on the principle of obtaining informative and high-quality images with minimal radiation exposure using radiation diagnostic methods: traditional radiography, multislice and cone-beam computed tomography.When conducting X-ray examinations, the main factors in reducing the risk of radiation exposure are the use of highly sensitive digital diagnostic image receivers, minimal exposure time, and a minimum number of images per examination. A lower current value and high anode voltage values, a minimum focal spot size, the placement of the tube as far as possible from the patient and the image receiver as close to the patient as possible, collimation of the radiation beam, and preference for a low radiation dose rate mode are also factors in reducing the risk of radiation exposure.Imaging of the craniovertebral region using cone beam computed tomography offers the opportunity to evaluate the bone structure of the region in detail, with an equal or less effective dose to the patient.
Multiparametric Quantitative MRI Evaluation of Changes in Brain Myelin Content after the First Course of Chemotherapy
Authors: Bondarenko V. P. , Kupriyanov D. A. , Artemov A. V. , Tereshchenko G. V. 
Published: May 2024

Objective. Quantitative assessment of changes in brain myelin content after the first course of chemotherapyMaterials and Methods. T1 and T2 maps as well as myelin water fraction (MWF) and macromolecular proton fraction (MPF) maps, reflecting myelin content, were acquired in 6 patients (mean age — 13.7 ± 2.4 years) before and after the first course of chemotherapy. The study was carried out using on 3T MRI scanner. Statistical data processing was carried out using the GraphPad Prism.Results. MPF and T2 values showed an increase in the thalamus and white matter of the occipital lobes of the brain, while MWF values showed an increase in the cerebellum and a decline in the white matter of the frontal lobes. Significant changes were not found for T1 values.Discussion. According to MWF the structures of the brain which are primarily affected by treatment with toxic drugs — the white matter of the frontal lobes and the cerebellum, were revealed. MWF values decreasing in the white matter of the frontal lobes may indicate the process of demyelination in this area, while increased MWF values in the cerebellum could be caused either by remyelination processes or by incomplete cleansing of myelin residues accumulation by macrophages at the site of degeneration. Conclusion. The results obtained demonstrated high potential of MWF values serve as early changes biomarker of neurotoxicity after the chemotherapy treatment. Along with this, the MPF index, which is more sensitive to cerebral edema, may be a predictor of demyelination.