bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parkinsonism, Psychomotor Slowing, Negative and Depressive Symptoms in Schizophrenia Spectrum and Mood Disorders: Exploring Their Intricate Nexus Using a Network Analytic Approach
Authors: Fritze Stefan , Brandt Geva A , Benedyk Anastasia , Moldavski Alexander , Volkmer Sebastian , Daub Jonas , Krayem Maria , Kukovic Jacqueline , Schwarz Emanuel , Braun Urs , Wolf Robert Christian , Kubera Katharina M , Northoff Georg , Meyer-Lindenberg Andreas , Tost Heike , Hirjak Dusan 
Published: April 2024

Abstract

Background and Hypothesis
Parkinsonism, psychomotor slowing, negative and depressive symptoms show evident phenomenological similarities across different mental disorders. However, the extent to which they interact with each other is currently unclear. Here, we hypothesized that parkinsonism is an independent motor abnormality showing limited associations with psychomotor slowing, negative and depressive symptoms in schizophrenia spectrum (SSD), and mood disorders (MOD).

Study Design
We applied network analysis and community detection methods to examine the interplay and centrality (expected influence [EI] and strength) between parkinsonism, psychomotor slowing, negative and depressive symptoms in 245 SSD and 99 MOD patients. Parkinsonism was assessed with the Simpson-Angus Scale (SAS). We used the Positive and Negative Syndrome Scale (PANSS) to examine psychomotor slowing (item #G7), negative symptoms (PANSS-N), and depressive symptoms (item #G6).

Study Results
In SSD and MOD, PANSS item #G7 and PANSS-N showed the largest EI and strength as measures of centrality. Parkinsonism had small or no influence on psychomotor slowing, negative and depressive symptoms in SSD and MOD. In SSD and MOD, exploratory graph analysis identified one community, but parkinsonism showed a small influence on its occurrence. Network Comparison Test yielded no significant differences between the SSD and MOD networks (global strength p value: .396 and omnibus tests p value: .574).

Conclusions
The relationships between the individual domains followed a similar pattern in both SSD and MOD highlighting their transdiagnostic relevance. Despite evident phenomenological similarities, our results suggested that parkinsonism is more independent of negative and depressive symptoms than psychomotor slowing in both SSD and MOD.
Go Ask Mom: The Gendered Dynamics of Color-Conscious Racial Socialization among White Parents
Authors: Kincaid Reilly , Underhill Megan R 
Published: April 2024

Abstract
While most white parents avoid discussing race and racism with their children or tell them to be color-blind, recent research suggests that a growing number of color-conscious white parents intentionally talk with their children about racism as an ongoing, systemic issue. However, this research gives little attention to parents’ gender. Using interviews with 28 color-conscious white heterosexual parents, we examine how and why gender influences parents’ race-related conversations with their children. We show that, in theory, mothers and fathers share similar beliefs about race/racism and the need to discuss it with their children. In practice, however, mothers overwhelmingly shoulder these conversations. We trace this paradox back to mothers’ distinctively color-conscious refashioning of intensive mothering practices—which involves both personal and community-level work at the race-parenting intersection—that fathers do not undertake. This gender gap in parents’ personal/community work around race influences contrasting approaches to race-related conversations with their children, with mothers being more proactive and fathers being more passive. This dynamic ultimately casts race as a “Mom topic” within color-conscious white families. We argue that this can inhibit more egalitarian realizations of color-conscious white racial socialization and carries important implications for the sustainability and outcomes of these efforts.
Supplementing narasin or monensin to control coccidiosis in naturally infected calves
Authors: Leiva Tiago , Cooke Reinaldo F , Lasmar Pedro V F , Valarelli Rodrigo L , De Simas José M C , Zapa Dina Maria B , Couto Luiz Felipe M , Heller Luciana M , Lopes Welber D Z 
Published: April 2024

Abstract
This experiment compared narasin and monensin as anticoccidials for calves naturally infected with Eimeria spp. Twenty-four weaned, non-castrated male calves (Bos indicus × B. taurus cross) were assigned to this experiment (days −8 to 42). All calves were infected by Eimeria spp. according to oocyst count per gram (OPG) from fecal samples collected on days −8 and −7 (average 1,059 ± 101 oocysts/g). Calves were housed in individual pens, received corn silage, mineral mix, and water for ad libitum consumption, in addition to a grain-based supplement at 200 g/head daily. Fecal samples were collected on days −2 and −1 for OPG, and results averaged as initial OPG value. Calves were blocked according to initial OPG into eight blocks of three calves each, ranked within each block according to body weight (BW) recorded on day −1, and assigned to receive narasin (NAR; 0.8 mg/kg of BW), monensin (MON; 1 mg/kg of BW), or no ionophore (CON; negative control). Ionophores were added to the grain-based supplement, and offered from days 0 to 42 of the experiment. Calf BW was recorded on days 7, 14, 21, 28, 35, and 42. Fecal samples were collected on days 6 and 7, 13 and 14, 20 and 21, 26 and 27, 34 and 35, and 41 and 42 for OPG analysis, and results from samples collected on consecutive days were averaged. Aliquoted fecal samples were also pooled across calves from the same treatment and collection days, and used to determine the prevalence of individual species of Eimeria. No treatment effects were detected (P ≥ 0.51) for calf BW or growth rate. A treatment × day interaction was detected (P &lt; 0.01) for OPG, as NAR and MON calves had less (P &lt; 0.01) OPG compared with CON calves beginning on day 7. The OPG was also less (P ≤ 0.03) in MON compared with NAR calves on days 7, 14, and 28, but did not differ (P ≥ 0.48) on days 21, 35, and 42. The anticoccidial efficacy of NAR and MON did not differ (P ≥ 0.16) when calculated across all Eimeria spp., or according to prevalence of E. bovis and E. alabamensins. A treatment × day interaction was detected (P = 0.04) for anticoccidial efficacy to E. alabamensis, which was greater (P &lt; 0.01) in MON calves on days 7 and 14 and did not differ (P ≥ 0.40) afterward. Collectively, both ionophores were similarly effective in controlling coccidiosis upon completion of the 42-d study, although the anticoccidial effects of monensin were noted earlier in the experiment. Nonetheless, these results corroborate narasin as an efficient anticoccidial ionophore for naturally infected calves.
Breeder age and hatching egg storage duration: effects on post-hatch performance of FUNAAB- α broiler chickens
Authors: Oke Oyegunle Emmanuel , Alo Ezekiel Taiwo , Oni Aderanti Ifeoluwa , Nwosu Emmanuela Uchenna , Wheto Mathew , Akinjute Obafemi Foluso , Imran-Oloko Galbat Oyindamola , Osisanwo Adeleke 
Published: April 2024

Abstract
This trial was designed to evaluate the influence of hatching egg storage length and broiler breeder hens’ age on post-hatch growth performance and physiological responses of FUNAAB-α chickens. Five hundred fertile eggs from each of 60 and 32-wk-old FUNAAB-α breeder hens were collected and assigned to five storage durations (0, 3, 7, 11, and 15 d). The hatching eggs were incubated using the conventional protocol. Data were collected on the growth performance and physiological responses. A 2 × 5 factorial design was used for the experiment. The results revealed that there was a decline in the final body weight in chickens from eggs of 15 and 11 d storage compared to the chickens from 7, 3, and 0 egg storage days. Chickens of 32-week-old breeder hens had higher (P &lt; 0.05) mean corpuscular volume, white blood cell, heterophil, and pack cell volume values compared to 60-week-old breeder hens. Hatchlings from 60-week-old breeders had a higher liver percentage (3.0% yolk-free body weight [YFBW]) than those from 32-week-old breeders (2.8% YFBW). It was concluded that an extended storage duration of 15 d adversely affected the carcass traits and growth performance of chickens from egg storage above seven days.
County-Level Cardiac Rehabilitation and Broadband Availability
Authors: DeLara David L. , Pollack Lisa M. , Wall Hilary K. , Chang Anping , Schieb Linda , Matthews Kevin , Stolp Haley , Pack Quinn R. , Casper Michele , Jackson Sandra L. 
Published: April 2024

Purpose:
Cardiac rehabilitation (CR) improves patient outcomes and quality of life and can be provided virtually through hybrid CR. However, little is known about CR availability in conjunction with broadband access, a requirement for hybrid CR. This study examined the intersection of CR and broadband availability at the county level, nationwide.

Methods:
Data were gathered and analyzed in 2022 from the 2019 American Community Survey, the Centers for Medicare & Medicaid Services, and the Federal Communications Commission. Spatially adaptive floating catchments were used to calculate county-level percent CR availability among Medicare fee-for-service beneficiaries. Counties were categorized: by CR availability, whether lowest (ie, CR deserts), medium, or highest; and by broadband availability, whether CR deserts with majority-available broadband, or dual deserts. Results were stratified by state. County-level characteristics were examined for statistical significance by CR availability category.

Results:
Almost half of US adults (n = 116 325 976, 47.2%) lived in CR desert counties (1691 counties). Among adults in CR desert counties, 96.8% were in CR deserts with majority-available broadband (112 626 906). By state, the percentage of the adult population living in CR desert counties ranged from 3.2% (New Hampshire) to 100% (Hawaii and Washington, DC). Statistically significant differences in county CR availability existed by race/ethnicity, education, and income.

Conclusions:
Almost half of US adults live in CR deserts. Given that up to 97% of adults living in CR deserts may have broadband access, implementation of hybrid CR programs that include a telehealth component could expand CR availability to as many as 113 million US adults.
Cardiopulmonary functional capacity in Taiwanese children with atrial septal defects
Authors: Xue Yu-Hao , Huang I-Ching , Tuan Sheng-Hui , Cheng Cheng-Chang , Cheng Hsuan , Lu Yen-Sen , Chou Chia-Chun , Chang Yung-Liang , Lin Ko-Long 
Published: April 2024

Background:
Most existing studies measure atrial septal defect (ASD) outcomes based on morbidity rates such as atrial arrhythmias and heart failure rather than the functional assessment of physical capacity postprocedure. Few studies have evaluated cardiopulmonary function in ASD children. This study represents the largest sample population in the current research, encompassing a total of 122 Taiwanese children with ASD who had undergone treatment, to evaluate cardiopulmonary functional capacity through the implementation of cardiopulmonary exercise testing (CPET), and to investigate whether variations in treatment may impact their cardiopulmonary function.

Methods:
This is a retrospective cohort study with the data collected from January 2010 to December 2021. All patients and controls (age-, sex-, and body mass index-matched) underwent CPET and pulmonary function testing.

Results:
In total, 122 ASD patients (surgically closed ASDs 27, transcatheter-closed ASDs 48, and follow-up unrepaired ASD 47) and 244 healthy controls were recruited. The ASD group exhibited lower peak metabolic equivalent (MET), peak oxygen consumption (VO2, p < 0.001), and peak minute ventilation (p = 0.028) along with MET and VO2 at the anaerobic threshold (AT) (p = 0.012) compared to the control group. No statistically significant differences were observed in the pulmonary function test. Among surgically closed, transcatheter closed and unrepaired ASD subgroups, no significant variances were seen in CPET and pulmonary function tests.

Conclusion:
Taiwanese ASD children exhibited diminished exercise capacity and cardiopulmonary performance compared to their healthy counterparts. Differences among specific ASD treatments in cardiopulmonary tests were non-significant.
Prevalence of Hearing Loss Among Noise-Exposed US Workers Within the Utilities Sector, 2010–2019
Authors: Masterson Elizabeth A. , Themann Christa L. 
Published: April 2024

Objective
This study’s objective was to estimate hearing loss prevalence for noise-exposed US Utilities workers.

Methods
In this cross-sectional study of a retrospective cohort, audiograms were examined for 1.3 million workers (13,595 within utilities) from 2010–2019. Hearing loss prevalence and adjusted risk as compared with a reference industry were estimated.

Results
The hearing loss prevalence for noise-exposed Utilities workers (25%) was higher than for noise-exposed workers in all industries combined (20%). Some subsectors surpassed the prevalence for all industries combined and/or had adjusted risks significantly higher than the reference industry. The highest prevalence subsectors were Hydroelectric Power Generation (37%) and steam and Air-Conditioning Supply (29%).

Conclusions
While often overlooked, noise-exposed workers in this sector have among the highest prevalences of hearing loss and significantly higher risks. Increased attention and better hearing conservation strategies are needed.
Development and validation of a preoperative radiomics-based nomogram to identify patients who can benefit from splenic hilar lymphadenectomy: a pooled analysis of three prospective trials
Authors: Xu Bin-bin , Zheng Hua-Long , Chen Chun-sen , Xu Liang-liang , Xue Zhen , Wei Ling-hua , Zheng Hong-hong , Shen Li-li , Zheng Chao-Hui , Li Ping , Xie Jian-Wei , Lin Jian-xian , Zheng Yu-hui , Huang Chang-Ming 
Published: April 2024

Background:
The authors aimed to use preoperative computed tomography images to develop a radiomic nomogram to select patients who would benefit from spleen-preserving splenic hilar (No.10) lymphadenectomy (SPSHL).

Methods:
A pooled analysis of three distinct prospective studies was performed. The splenic hilar lymph node (SHLN) ratio (sLNR) was established as the quotient of the number of metastatic SHLN to the total number of SHLN. Radiomic features reflecting the phenotypes of the primary tumor (RS1) and SHLN region (RS2) were extracted and used as predictive factors for sLNR.

Results:
This study included 733 patients: 301 in the D2 group and 432 in the D2+No.10 group. The optimal sLNR cutoff value was set at 0.4, and the D2+No.10 group was divided into three groups: sLNR=0, sLNR ≤0.4, and sLNR >0.4. Patients in the D2+No. 10 group were randomly divided into the training (n=302) and validation (n=130) cohorts. The AUCs value of the nomogram, including RS1 and RS2, were 0.952 in the training cohort and 0.888 in the validation cohort. The entire cohort was divided into three groups based on the nomogram scores: low, moderate, and high SHLN metastasis burden groups (LMB, MMB, and HMB, respectively). A similar 5-year OS rate was found between the D2 and D2+No. 10 groups in the LMB and HMB groups. In the MMB group, the 5-year OS of the D2+No. 10 group (73.4%) was significantly higher than that of the D2 group (37.6%) (P<0.001).

Conclusions:
The nomogram showed good predictive ability for distinguishing patients with various SHLN metastasis burdens. It can accurately identify patients who would benefit from SPSHL.
Impact of blood salvage therapy during oncologic liver surgeries on allogenic transfusion events, survival, and recurrence: an ambidirectional cohort study
Authors: Lugassy Liav , Marion Samuel , Balthazar Frédéric , Cheng Oviedo Sonia G. , Collin Yves 
Published: April 2024

Introduction:
The use of autologous blood transfusions in oncologic surgeries is somewhat controversial due to the potential risk of disease dissemination through the salvage process. On the other hand, autologous blood transfusion can prevent the potential negative effects of allogenic blood transfusions and reduce use of valuable resources.

Methods:
This study included 106 adult patients who underwent oncologic liver surgery at our institution between December 2015 and June 2019. The patients were divided into two groups: the Cell Saver group (operated between January 2018 and June 2019) and the control group (operated between December 2015 and December 2017). The Cell Saver device was present in the operating room for the Cell Saver group, and blood was retransfused if a certain amount of blood loss occurred. Data analysis focused on outcomes such as blood transfusion requirements, overall survival, recurrence-free survival, hemoglobin levels, hospital stay, and complications. Patient records provided relevant information on demographics, surgery details, pathology, and outcomes for both groups.

Results:
Autologous blood transfusion was found to reduce the amount of blood units needed (4.0 units (control group) versus 0.4 units (Cell Saver group) P=0.029. Kaplan–Meier curves showed no difference for both overall survival 471.6 days (Cell Saver group) versus 468.3 days (control group) (P=0.219) and 488.9 days (Cell Saver group) versus 487.2 days (control group) (P=0.993) and disease-free survival (P=0.553) and (P=0.735) for primary hepatic tumors and hepatic metastasis respectively between the Cell Saver and control groups. Overall survival regardless of the type of tumor was similar to the control group (485.4 days vs. 481.9 days) (P=0.503). Survival was significantly lower for minor hepatectomies (516.0 days vs. 517.4 days) (P=0.050) in the Cell Saver group, major hepatectomies showed no difference in overall survival (470.2 days vs. 466.4 days) (P=0.868). No impact on disease recurrence was found between patients who received autologous blood transfusions versus those who did not.

Conclusion:
The use of Cell Saver should not be avoided in oncologic surgeries of the liver. Use of Cell Saver for major hepatectomies might be more beneficial as OS was significantly lower for the Cell Saver group for patients who underwent minor hepactomies. Further research is needed to explain this conflicting result. Nonetheless, the use of Cell Saver in autologous blood transfusions can reduce the use of valuable resources and the risks associated with allogenic blood transfusions.
Eosinophilic pulmonary disease with ulcerative colitis: A case report
Authors: Li Songtao , Fang Mingliang , Guo Hua , Yu Tian , Wang Jun , Li Weiming , Huang Yunong , Wang Xichuan , Wu Rongyi 
Published: April 2024

Rationale:
Eosinophilic pulmonary disease (EPD) is a general term for a large group of diseases with complex etiology. Ulcerative colitis is an inflammatory bowel disease (IBD). Patients with IBD may have pulmonary involvement. We herein present a case of ulcerative colitis complicated with EPD.

Patient concerns:
A 34-year-old woman with ulcerative colitis presented with dry cough. She had peripheral eosinophilia and apical ground glass opacities on CT (computed tomography) of her chest. Antibiotic treatment was ineffective.

Diagnoses:
Lung biopsy revealed eosinophil infiltration in the alveolar space and interstitial space, so EPD was considered.

Interventions:
After oral administration of prednisone, the lung shadow on CT disappeared when the cough symptoms resolved. However, the symptoms recurred after drug withdrawal, and the lung shadow reappeared on imaging. The cough symptoms and lung shadow disappeared after oral prednisone was given again. Prednisone was slowly discontinued after 6 months of treatment.

Outcomes:
The patient stopped prednisone for half a year. No recurrence or abnormal CT findings were detected during the half-year follow-up.

Lessons:
The clinical manifestations of EPD are atypical, laboratory and imaging findings are not specific, and it is difficult to make a definite diagnosis before lung biopsy. The diagnosis depends on pathological examination. Glucocorticoid treatment is effective, but some patients may relapse after drug withdrawal. Active follow-up after glucocorticoid treatment is very important for identifying disease recurrence. Patients with IBD are relatively prone to developing EPD. The etiology of EPD is complex. In clinical practice, we need to make a diagnosis and differential diagnosis to clarify its etiology.
Comparative analysis of different therapeutic approaches in the management of protein-energy malnutrition: Case reports from a clinical setting
Authors: Elendu Chukwuka , Amaechi Dependable C. , Jingwa Klein A. , Elendu Tochi C. 
Published: April 2024

Background:
Severe protein-energy malnutrition (PEM) presents a significant clinical challenge, often compounded by comorbidities such as type 2 diabetes. This case report aims to elucidate the intricacies of managing severe PEM in conjunction with type 2 diabetes, emphasizing the importance of personalized interventions and multidisciplinary collaboration in achieving optimal outcomes. By addressing the unique challenges this complex clinical scenario poses, this report contributes valuable insights to the medical literature and guides clinicians in effectively managing similar cases.

Methods:
The patient, pseudonymously identified as Emma Thompson, underwent a comprehensive diagnostic evaluation to assess her symptoms’ severity and underlying causes. This included a thorough physical examination, laboratory testing, imaging studies, and collaboration with specialists to formulate a tailored treatment plan. Interventions were meticulously administered, with dosages, strengths, and durations adjusted based on ongoing assessments and patient response.

Results:
Implementing multidisciplinary therapeutic interventions significantly improved the patient’s nutritional status, glycemic control, and overall well-being. Objective measures such as BMI, serum albumin levels, and physical functioning showed marked improvement throughout treatment. Patient-reported outcomes indicated enhanced quality of life, reduced fatigue, and increased energy levels, underscoring the comprehensive success of the integrated therapeutic approach.

Conclusion:
This case report highlights the efficacy of a holistic, patient-centered approach in managing severe PEM and comorbid type 2 diabetes. Optimal outcomes were achieved by addressing the complex interplay of medical conditions through tailored interventions and multidisciplinary collaboration. The lessons from this case underscore the importance of individualized care, ongoing assessment, and long-term follow-up in enhancing patient well-being and guiding future clinical practice.