bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of FDG‐PET as a biological marker for predicting the hypoxic status of tongue cancer
Authors: Han Myung Woul , Lee Hee Jin , Cho Kyung–Ja , Kim Jae Seung , Roh Jong–Lyel , Choi Seung–Ho , Nam Soon Yuhl , Kim Sang Yoon 
Published: November 2011

AbstractBackgroundTo determine whether 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET) could serve as a useful technique predicting tumor hypoxia and prognosis in tongue cancer, we assessed the relationship between FDG uptake and the levels of hypoxia‐related markers.MethodsTumor uptake of FDG in 33 patients with T2 tongue cancer was assessed by measuring maximum standardized uptake values (SUVmax). Expression of hypoxia‐inducible factor (HIF)‐1α, carbonic anhydrase (CA)‐9, glucose transporter (GLUT)‐1, and erythropoietin receptor (EPOR), was determined by immunohistochemical staining. Correlation between SUVmax and the expression of hypoxia‐related markers was assessed and multivariate analysis was performed to determine what parameters affected clinical outcomes.ResultsWe observed strong correlations between SUVmax and expression of HIF‐1α (p < .05), CA‐9 (p < .01), and GLUT‐1 (p < .01). SUVmax, HIF‐1α expression, and tumor grade were significant independent predictors of disease‐free survival (DFS).ConclusionSUVmax may be a good noninvasive biomarker for prediction of hypoxic status and prognosis of patients with T2 tongue cancer. © 2011 Wiley Periodicals, Inc. Head Neck, 2011
Comparative analysis of a geomorphology‐based instantaneous unit hydrograph in small mountainous watersheds
Authors: López J. J. , Gimena F. N. , Giráldez J. V. , Ayuso J. L. , Goñi M. 
Published: November 2011

AbstractA conceptual insytnataneous unit hydrograph (IUH) based on geomorphologival association of linear reservoirs (GR) previously developed by the authors has been compared with other IUH models: a distributed GR variation (GR(v)), the Nash IUH, the Chutha and Dooge IUH, and the Troutman and Karlinger IUH for the analysis of direct runoff hydrographs recorded in three experimental watershed of the north of Spain. The comparison was made through a calibration‐validation process in which a leave‐one‐out cross‐validation method was applied. The results indicate the satisfactory performance of all the models, with the advantage for the GR model of the dependence on only one parameter, which can be identified from the watershed and event characteristics. This property makes its use easier than that of other models. Copyright © 2011 John Wiley & Sons, Ltd.
A systems perspective on the integrative child psychiatry approach. Discussion of paper: “Working here and now with the individual and family system: A case of a traumatized child”
Authors: Fivaz‐Depeursinge Elisabeth 
Published: November 2011

AbstractIn this discussion, after a few general comments, I will propose a systems reading of the intervention so elegantly described by Kaija Puura. I will draw parallels between the therapeutic and the family groups as framing‐developing systems and formalize the steps taken by the family toward healing under the influence of the therapist's team.
Temporal stability of alexithymia in cancer patients following a psychological intervention
Authors: Porcelli Piero , Tulipani Cinzia , Di Micco Concetta , Spedicato Maria R. , Maiello Evaristo 
Published: November 2011

AbstractObjective: The state‐trait nature of alexithymia is not fully resolved. The aim of this article was to evaluate the temporal stability of alexithymia in cancer patients after psychological intervention. Design: Absolute and relative stability of alexithymia was evaluated in 104 cancer patients who received multicomponent psychological treatment or usual medical care. Results: Alexithymia scores significantly decreased in treated patients and increased in the control group, thus showing that the lack of absolute stability (i.e., the change of personality scores over time) likely was because of the effect of the treatment versus the control condition. The relative stability (i.e., the extent to which the inter‐individual differences remain the same over time) of alexithymia after 6 months was, however, demonstrated with multiple regressions, after controlling for anxiety, depression, and cancer‐related pain. Conclusions: This study confirms the relative stability of alexithymia and that the lack of absolute stability of the construct is influenced by psychological intervention in cancer patients. © 2011 Wiley Periodicals, Inc. J Clin Psychol 67:1–11, 2011.
Clinical evaluation of multiplex real‐time PCR panels for rapid detection of respiratory viral infections
Authors: Sanghavi Sonali K. , Bullotta Arlene , Husain Shahid , Rinaldo Charles R. 
Published: November 2011

AbstractRespiratory viral infections are one of the leading causes of morbidity and mortality, particularly in children, the elderly and immunocompromised persons. Rapid identification of viral etiology is critical in ruling out non‐viral infections, initiating antiviral treatment and limiting the spread of the infection. Multiplex assays of more than one viral gene target in a single tube have the advantage of rapid screening of a large number of potential viral pathogens in a short time. A multiplex real‐time PCR assay was used in this study for detection of respiratory RNA and DNA viral infections in 728 specimens received from 585 adult and pediatric patients comprised of symptomatic and asymptomatic organ transplant recipients and non‐recipients for diagnosis of respiratory illnesses and for routine clinical monitoring. Multiplex PCR was more sensitive than the multiplex immunofluoresence culture assay (R‐mix) and also detected additional respiratory viruses that were not covered by the R‐mix panel. The number of respiratory viruses detected in symptomatic patients was significantly higher than asymptomatic patients in both adult and pediatric patients. Herpesviral infections were the predominant cause of lower respiratory tract infection in the organ transplant recipients, whereas respiratory syncytial virus was the most common pathogen in non‐transplant patients particularly children. Multiplex real‐time PCR for detection of respiratory viruses has the potential for rapid identification of viral pathogens. In this era of emerging viral infections, addition of newer viral targets to the multiplex PCR panels will be beneficial in determining both patient management and public health epidemiology. J. Med. Virol. 84:162–169, 2011. © 2011 Wiley Periodicals, Inc.
Evolution of Anelloviridae strains distribution in serial blood and biopsy samples from a renal transplant patient
Authors: Biagini Philippe , Bédarida Sandra , Dussol Bertrand , Daniel Laurent , Berland Yvon , de Micco Philippe 
Published: November 2011

AbstractA few studies investigated the natural history of viruses belonging to the family Anelloviridae in transplant patient. The case of a 64‐year‐old kidney transplant recipient is described. Molecular analysis of serial blood samples collected before and after transplant was performed during a period of 510 days. Two kidney biopsies were also analyzed. All blood samples tested positive for Anelloviridae DNA, with the identification of sequences belonging to the three taxonomic genera identified in humans. Sequences distribution during the follow‐up was multimodal. A sequence nearly identical to one present in the blood before transplant was further characterized in one biopsy sample. J. Med. Virol. 84:96–98, 2011. © 2011 Wiley Periodicals, Inc.
BapC autotransporter protein of Bordetella pertussis is an adhesion factor
Authors: Bokhari Habib , Bilal Iram , Zafar Sadia 
Published: November 2011

AbstractBordetella pertussis, the causative agent of whooping cough, attaches to mucosal surfaces in upper respiratory tract, where it produces, a variety of surface‐associated and secreted molecules. Among various secreted products, some of the proteins belonging to autotransporter family; pertactin (Prn), bordetella resistance to killing (BrkA) and a newly identified member, bordetella autotransporter protein‐C (BapC), are investigated in this study for their adherence potential to various respiratory and non‐respiratory tract specific cell lines. Our results reveal that BapC and Prn mutants adhere significantly less (p < 0.0001 and p < 0.05) respectively to human non‐respiratory (HeLa‐229) and murine macrophages (P‐388 D‐1) cells compared to their wild‐type strains. Prn, BrkA and BapC share no homology in their passenger domains except existence of common motifs arginine‐glycine‐asparctic (RGD) and glycosaminoglycan binding site (SGXG). We have shown that RGD and SGXG motifs are present in the coiled region in Prn and BrkA proteins with the exception in BapC where R (463) of RGD and S (597) of SGXG motif were observed in beta sheet of the modeled protein structures. Therefore, there is possibility that such arrangement of motifs can confer greater probability of BapC in better selective adherence to binding sites on the HeLa‐229 and P‐388 D‐1 cell lines. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
A statistical approach to multi‐site multivariate downscaling of daily extreme temperature series
Authors: Khalili Malika , Van Nguyen Van Thanh , Gachon Philippe 
Published: November 2011

AbstractDownscaling methods for describing the linkage between global‐scale climate variables and local climatic conditions have been frequently used in climate‐related impact assessment studies. Previous works, however, have been mainly dealing with downscaling of climatic processes for a single site, but very few studies are concerned with the downscaling of these processes for multi‐sites because of the complexity in accurately describing both observed at‐site temporal persistence and spatial dependence between different locations. In the present study, a multi‐site multivariate statistical downscaling (SD) approach was developed for simulating daily maximum (Tmax) and minimum (Tmin) temperature series at many sites concurrently. The proposed approach consists of a combination of a linear regression component to describe the linkage between global climate predictors and local temperature extremes, and a stochastic component based on a spatial moving average process to reproduce the observed spatial dependence between temperature extremes at different sites. The feasibility of the suggested SD method was assessed using observed daily extreme temperature data available at 10 weather stations located in the southwest region of Quebec and the southeast region of Ontario in Canada, as well as climate predictors from the NCEP/NCAR (National Centers for Environmental Prediction/National Centre for Atmospheric Research) reanalysis dataset for the 1961–1990 period. It was found that the proposed SD approach was able to accurately describe various Tmax and Tmin characteristics, including their spatial and temporal variation as well as their interannual anomalies. In addition, comparison of the results from the proposed multi‐site multivariate SD method and one simulation series from the Canadian Regional Climate Model (CRCM) at a 45‐km resolution (a dynamic downscaling procedure) has indicated that the suggested SD approach was able to more accurately describe the observed spatial and temporal characteristics of extreme temperature series at the regional scale than the CRCM‐based dynamic downscaling method. Copyright © 2011 Royal Meteorological Society
Wave front sets for ultradistribution solutions of linear partial differential operators with coefficients in non‐quasianalytic classes
Authors: Albanese A. A. , Jornet D. , Oliaro A. 
Published: November 2011

AbstractWe prove the following inclusionwhereWF*denotes the non‐quasianalytic Beurling or Roumieu wave front set, Ω is an open subset of\documentclass{article}\usepackage{amssymb}\begin{document}\pagestyle{empty}$\mathbb {R}^n$\end{document},Pis a linear partial differential operator with suitable ultradifferentiable coefficients, and Σ is the characteristic set ofP. The proof relies on some techniques developed in the study of pseudodifferential operators in the Beurling setting. Some applications are also investigated.
Regularity results of Stokes/Lamé interface problems
Authors: Mercier D. , Nicaise Serge 
Published: November 2011

AbstractThis paper is devoted to some transmission problems involving the Lamé and stationary Stokes systems in two‐dimensional nonsmooth domains. We first show that these problems may be obtained as a limit of a transmission Lamé problem when the Lamé coefficient λ goes to infinity. We further investigate the behavior of the solutions of these problems near geometrical singularities, especially near corner points where the interface intersects the boundaries. In particular we show stable decompositions with respect to the perturbation parameter λ. Some minimal regularity results are deduced from similar minimal regularity result of transmission Lamé problems obtained in 13. Some numerical results for the calculation of the singular exponents in the asymptotic expansion are presented and confirm these minimal regularity results.
Simulation studies on the motor unit potentials with satellite components in amyotrophic lateral sclerosis and spinal muscle atrophy
Authors: Zalewska Ewa , Rowinska‐Marcinska Katarzyna , Gawel Małgorzata , Hausmanowa‐Petrusewicz Irena 
Published: November 2011

AbstractIntroduction: We compared motor unit potentials (MUPs) with satellite components recorded in two anterior horn disorders: amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA, types II and III). Methods: We analyzed MUPs recorded from biceps brachii muscle, including 209 associated with ALS (12 patients) and 127 with SMA (5 patients). Simulations were applied to determine the origin of satellites in these processes. Results: MUP parameters differ in ALS and SMA. Simulations indicate that the satellite potential in ALS often originated from a single fiber, whereas in SMA it originated from a group of fibers of smaller diameters than the surrounding ones. Conclusions: These results suggest that, except for neurogenic factors, the variability of muscle fiber diameters also leads to the formation of MUPs with satellites. This variability seems to be responsible for the differences in the shape of the main and satellite MUP components in ALS and SMA. Muscle Nerve, 2012
A Markov‐modulated fluid flow queueing model under D‐policy
Authors: Baek Jung Woo , Lee Ho Woo , Lee Se Won , Ahn Soohan 
Published: November 2011

SUMMARYWe consider a Markov‐modulated fluid flow queueing model under D‐policy. As soon as the fluid level reaches zero, the server becomes idle. During the idle period, fluid arrives from outside according to an underlying continuous time Markov chain (UMC) and the idle server does not process the fluid. We consider two increase patterns of fluid during the idle period: vertical increase (Type‐V) and linear increase (Type‐L). The idle server is reactivated only when the cumulative fluid level in the system exceeds a predetermined threshold value D. We derive the distributions of fluid level and mean performance measures for both types. We also present cost optimization model to minimize average operating cost per unit time. Copyright © 2011 John Wiley & Sons, Ltd.
Preparative Separation of Methylswertianin, Swerchirin and Decussatin from the Tibetan Medicinal Plant Swertia Mussotii Using High‐speed Counter‐current Chromatography
Authors: Jia Jing , Chen Tao , Wang Ping , Chen Guichen , You Jinmao , Liu Yongjun , Li Yulin 
Published: November 2011

ABSTRACTIntroductionXanthones, the primary constituents of Swertia mussotii, are known to possess a variety of biological activities, including anti‐depressant, anti‐leukaemic, anti‐tumour, anti‐tubercular, choleretic, diuretic, anti‐microbial, anti‐fungal, anti‐inflammatory, anti‐viral, cardiotonic and hypoglycemic properties. However, high performance, environmentally friendly methods for isolating and purifying xanthones from S. mussotii are not currently available.ObjectiveTo develop a high performance and environmentally friendly method for the preparative separation of xanthones methylswertianin, swerchirin and decussatin from S. mussotii using high‐speed counter‐current chromatography (HSCCC).MethodologyA solvent system composed of n‐hexane:ethyl acatate:methanol:water (5:5:10:4, v/v/v/v) was developed for the separation method. The upper phase was used as the stationary phase, and the lower phase was used as the mobile phase at a flow rate of 1.5 mL/min, a rotation speed of 800 rpm and a temperature of 25 °C.ResultsUsing the described method, 8 mg of methylswertianin, 21 mg of swerchirin and 11 mg of decussatin with purities of over 98% could be isolated from a 150 mg crude sample. They were identified by 1H‐NMR and 13 C‐NMR analysis.ConclusionThree xanthones in Swertia mussotii could be systematically isolated and purified using HSCCC. Copyright © 2011 John Wiley & Sons, Ltd.
Two‐stage method to remove population‐ and individual‐level outliers from longitudinal data in a primary care database
Authors: Welch C. , Petersen I. , Walters K. , Morris R. W. , Nazareth I. , Kalaitzaki E. , White I. R. , Marston L. , Carpenter J. 
Published: November 2011

ABSTRACTPurposeIn the UK, primary care databases include repeated measurements of health indicators at the individual level. As these databases encompass a large population, some individuals have extreme values, but some values may also be recorded incorrectly. The challenge for researchers is to distinguish between records that are due to incorrect recording and those which represent true but extreme values. This study evaluated different methods to identify outliers.MethodsTen percent of practices were selected at random to evaluate the recording of 513,367 height measurements. Population‐level outliers were identified using boundaries defined using Health Survey for England data. Individual‐level outliers were identified by fitting a random‐effects model with subject‐specific slopes for height measurements adjusted for age and sex. Any height measurements with a patient‐level standardised residual more extreme than ±10 were identified as an outlier and excluded. The model was subsequently refitted twice after removing outliers at each stage. This method was compared with existing methods of removing outliers.ResultsMost outliers were identified at the population level using the boundaries defined using Health Survey for England (1550 of 1643). Once these were removed from the database, fitting the random‐effects model to the remaining data successfully identified only 75 further outliers. This method was more efficient at identifying true outliers compared with existing methods.ConclusionsWe propose a new, two‐stage approach in identifying outliers in longitudinal data and show that it can successfully identify outliers at both population and individual level. Copyright © 2011 John Wiley & Sons, Ltd.
Effect of carbon containing SiNx antireflection coating on the screen‐printed contact and low illumination performance of silicon solar cell
Authors: Kang Moon Hee , Rohatgi Ajeet , Hong Junegie , Rounsaville Brian , Upadhyaya Vijaykumar , Ebong Abasifreke , Das Arnab 
Published: November 2011

ABSTRACTScreen‐printed metal contact formation through a carbon containing antireflection coating was investigated for silicon solar cells by fabricating conventional carbon‐free SiNx and carbon‐rich SiCxNy film. An appreciable difference was found in the average shunt resistance (Rsh), which was about an order of magnitude higher for SiCxNy‐coated solar cells relative to the counterpart SiNx‐coated solar cells. Series resistance (Rs) and fill factor (FF) were comparable for both antireflection coatings but the starting efficiency of SiCxNy‐coated cell was ~0·2% lower because of slightly inferior surface passivation. However, SiCxNy‐coated solar cells showed less degradation under lower illumination (<1000 W/m2) compared with the SiNx‐coated cells due to reduced FF degradation under low illumination. Theoretical calculations in this paper support that this is a direct result of high Rsh. Detailed photovoltaic system and cost modeling is performed to quantify the enhanced energy production and the reduced levelized cost of electricity due to higher shunt resistance of the SiCxNy‐coated cells. It is shown that Rsh value below 30 Ω (7000 Ω cm2 for 239 cm2 cell) can lead to appreciable loss in energy production in regions of low solar insolation. Copyright © 2011 John Wiley & Sons, Ltd.
Innovation and fabrication of 5.5 generation image‐patterned translucent photovoltaic module by using laser scribing technology
Authors: Lien Shui‐Yang , Hsu Chia‐Hsun , Ou Yu‐Chih 
Published: November 2011

ABSTRACTThe building‐integrated photovoltaic (PV) technology is one of the most promising applications for amorphous silicon (a‐Si) thin film solar cells. It is necessary to develop more various building‐integrated PV modules, which will provide architects and industries more options for the PV installation to their buildings or construction bodies. In this paper, a new type of a‐Si PV module, called image‐patterned translucent a‐Si PV module, is developed. Any required image can be displayed on the module by using laser processes. In the present result, a 5.5 generation (1100 × 1400 mm) image‐patterned translucent PV module with 10% transmittance exhibits the stabilized maximum power output (Pmax) of 92.5 W, which can be further improved by optimizing the laser parameters. The remarkable features of our module such as the image displaying, natural light transmission, and heat reduction create entirely new applications including windows and logos and provide an option that adds personal style and unique design to the building interiors. Copyright © 2011 John Wiley & Sons, Ltd.
In der Schwebe
Authors: Becker Michael , Meiser Jerome , Koblischka Michael R. , Hartmann Uwe 
Published: November 2011

AbstractEine Leviationswaage kann die Levitationskraft zwischen einer Hochtemperatur‐Supraleiter‐Probe und einem Permanentmagneten in Abhängigkeit des Abstands zwischen beiden messen. Der Artikel stellt eine Waagenkonstruktion vor, die sich für Praktika in Hochschulen und Schulen eignet. Der Versuch läuft computergesteuert. Für den Einsatz in fortgeschrittenen Semestern ist besonders interessant, dass man aus der Levitationskraft die kritische Stromdichte und das Haftkraftpotential der Flussschläuche in der Probe errechnen kann.
Streit um das Unsichtbare
Authors: Bührke Thomas 
Published: November 2011

AbstractNach dem heutigen Standardmodell der Kosmologie besteht 23 % aller im Universum vorhandenen Materie aus nicht‐baryonischen Elementarteilchen. Den Löwenanteil stellt die Dunkle Energie (72 %), während die uns bekannte, baryonische Materie nur knapp 4, 6 % ausmacht. Seit Jahren laufen in Untergrundlaboratorien extrem empfindliche Experimente zum Nachweis der Dunkle‐Materie‐Teilchen. Jüngst gab es Meldungen, wonach einige Gruppen Hinweise auf solche Teilchen gefunden haben. Noch sind die Ergebnisse jedoch widersprüchlich.