bluuebunny/crossref_metadata_2025_split huggingface dataset:
KARATERISTIK KIMIA DAN ORGANOLEPTIK INSTAN SAGU (Metroxylon SP) SEBAGAI MAKANAN BERKALORI TINGGI
Authors: Kiay Nancy , Abdullah Sofyan 
Published: May 2024

Penelitian ini bertujuan untuk menghasilkan produk instan sagu yang memiliki kandungan kalori yang tinggi dan diterima oleh konsumen dan menghasilkan informasi profil produk (Karateristik kimia/nutrisi produk dan organoleptik). Formula dibuat dengan menambahkan beberapa bahan lain sehingga diperoleh bentuk pangan instan dengan jumlah kalori yang memenuhi syarat sebagai pangan tinggi kalori. Penelitian tahap pertama dilakukan optimasi proses dengan Pembuatan pati sagu, pembuatan tepung kacang merah, dan tepung kedelai, selanjutnya penyusunan formula dan pembuatan instan sagu dan dilakukan analisis kimia yaitu analisis kadar air, kadar abu dan analisa proksimat (Protein, Lemak dan Karbohidrat), Penentuan Nilai Kalori Makanan serta Uji Organoleptik tingkat kesukaan panelis terhadap warna, aroma, rasa dan tekstur instan sagu. Penelitian ini menggunakan rancangan acak lengkap (RAL), sehingga data yang diperoleh dianalisis dengan menggunakan statistik. Perbedaan yang signifikan antar kelompok dianalisis menggunakan ANOVA dengan p <0,05. Jika ada perbedaan yang signifikan antar kelompok, data dianalisis dengan uji Duncan multiple range test (DMRT). Hasil analisis menunjukkan bahwa formula sagu instan mempunyai kadar air berkisar antara 4,47 – 5,29% (bb), kadar abu 1,90 – 2,61% (bk), protein 8,18 – 13,40% (bk), lemak 7,66 – 11,03% (bk), dan karbohidrat 77.77 – 67,35% (bk). Dari data tersebut diperoleh nilai kalori produk sebesar 412,71– 422,24 kkal per 100 g bahan (% bk). Nilai kalori tersebut memenuhi standar pangan berkalori menurut BPOM (2004), yaitu minimal harus mempunyai 300 kkal per 100 g bahan. Hasil uji organoleptik terhadap parameter warna, aroma, citarasa dan tekstur menunjukkan rata-rata panelis memberikan penilaian suka terhadap produk instan sagu yang dihasilkan dari semua formula. Kesimpulan dari penelitian ini adalah formula dengan komposisi 45% pati sagu, 10% tepung kacang merah dan 10% tepung kedelai, 20% skim, 10% gula, dan 5% minyak nabati merupakan formula terbaik. Dari penilaian organoleptik terhadap warna, aroma, citarasa dan tekstur diperoleh kriteria suka sampai sangat suka dan memenuhi standar sebagai makanan instan.
A Study of Learning Obstacles: Determining Solutions of a System of Linear Equation Using Gauss-Jordan Method
Authors: Siahaan Meiva Marthaulina Lestari , Fitriani  , Leli Angelika Rosa Da Lima 
Published: May 2024

Salah satu metode pencarian solusi SPL yang dipelajari di pendidikan tinggi adalah metode Gauss-Jordan. Berdasarkan data penelitian, mahasiswa melakukan kesalahan dalam melakukan operasi baris elementer (OBE), membentuk ke dalam matriks yang diperbesar, dan bahkan pemahaman mendasar mengenai reduksi baris dan ini berpengaruh dalam menentukan solusi suatu SPL. Untuk itu perlu dianalisis hambatan belajar yang terjadi dalam menentukan solusi SPL menggunakan metode Gauss-Jordan. Peneitian ini merupakan penelitian kualitatif dan merupakan bagian dari Didactical Design Research (DDR). Penelitian ini dilaksanakan di salah satu universitas di Nusa Tenggara Timur (NTT) dengan subjek penelitian merupakan 20 mahasiswa calon guru matematika. Teknik penelitian ini adalah tes diagnostik dan wawancara. Hasil penelitian menunjukkan beberapa hambatan yang dialami mahasiswa adalah keterbatasan pemahaman pada OBE, pengklasifikasian MEBT, dan merepresentasikan MEBT ke dalam solusi SPL. Rekomendasi dari penelitian ini adalah pengajar hendaknya membuat suatu bahan ajar yang dapat meminimalisir hambatan belajar yang dialami mahasiswa.

One of many methods of finding solution of a system of linear equations (SLE) studied in higher education is the Gauss-Jordan method. Based on the research, students made mistakes in performing elementary row operations (ERO), forming into augmented matrices, and even basic understanding of row subtraction and this has an effect on determining the solution of an SLE. For this reason, it is necessary to analyze the learning obstacles that occur in determining the solution of LES using the Gauss-Jordan method. This qualitative research is part of the Didactical Design Research (DDR). This research was conducted at a university in East Nusa Tenggara (NTT) involving 20 students as preservice mathematics teacher. The technique of this research is diagnostic test and interview. The results show that some of the obstacles faced by students are insufficient understanding of ERO, classifying reduced row-echelon form (RREF), and representing MEBT into SPL solutions. This study recommends that teachers create teaching materials that minimizes learning obstacles experienced by students.
The clinical and imaging data fusion model for single-period cerebral CTA collateral circulation assessment
Authors: Ma Yuqi , He Jingliu , Tan Duo , Han Xu , Feng Ruiqi , Xiong Hailing , Peng Xihua , Pu Xun , Zhang Lin , Li Yongmei , Chen Shanxiong 
Published: May 2024

BACKGROUND: The Chinese population ranks among the highest globally in terms of stroke prevalence. In the clinical diagnostic process, radiologists utilize computed tomography angiography (CTA) images for diagnosis, enabling a precise assessment of collateral circulation in the brains of stroke patients. Recent studies frequently combine imaging and machine learning methods to develop computer-aided diagnostic algorithms. However, in studies concerning collateral circulation assessment, the extracted imaging features are primarily composed of manually designed statistical features, which exhibit significant limitations in their representational capacity. Accurately assessing collateral circulation using image features in brain CTA images still presents challenges. METHODS: To tackle this issue, considering the scarcity of publicly accessible medical datasets, we combined clinical data with imaging data to establish a dataset named RadiomicsClinicCTA. Moreover, we devised two collateral circulation assessment models to exploit the synergistic potential of patients’ clinical information and imaging data for a more accurate assessment of collateral circulation: data-level fusion and feature-level fusion. To remove redundant features from the dataset, we employed Levene’s test and T-test methods for feature pre-screening. Subsequently, we performed feature dimensionality reduction using the LASSO and random forest algorithms and trained classification models with various machine learning algorithms on the data-level fusion dataset after feature engineering. RESULTS: Experimental results on the RadiomicsClinicCTA dataset demonstrate that the optimized data-level fusion model achieves an accuracy and AUC value exceeding 86%. Subsequently, we trained and assessed the performance of the feature-level fusion classification model. The results indicate the feature-level fusion classification model outperforms the optimized data-level fusion model. Comparative experiments show that the fused dataset better differentiates between good and bad side branch features relative to the pure radiomics dataset. CONCLUSIONS: Our study underscores the efficacy of integrating clinical and imaging data through fusion models, significantly enhancing the accuracy of collateral circulation assessment in stroke patients.
DC Resistivity and Electromagnetic Induction Techniques for Soil Characterization in the Agriculture Land (Case Study in Cidadap, West Bandung, West Java)
Authors: Widodo Widodo 
Published: May 2024

ABSTRACTS Precision farming or precision agriculture is generally defined as information- and technology-based methods used for agricultural optimization. This concept can be applied to increase crop production and minimize the effect of the massive fertilizer use on the environment. The implementation of precision farming develops specific rules based on soil and hydrogeological properties that allow farmers to obtain more information for their crop management. This study used direct Current (DC) geoelectrical and electromagnetic (EM) methods to get the land’s water distribution data by measuring the soil’s resistivity and conductivity. Both methods are best used on preliminary surveys of precision farming because this method could measure the resistivity and conductivity of subsurface properties in the field and green environmental techniques. Measurements were made on agricultural land located in Parompong, Lembang, West Java. ARES II was used to measure the resistivity value, while EM38-MK2 was used to measure the conductivity value. From the processing results and its correlation with the pit test, the resistivity values were obtained in the 15-170 Ω.m range, while the conductivity values were 2-115 mS/m. There are good correlations between geophysical data and test pit data, which correspond to the resistive layers at a depth of 0.75 m and the conductive part at a depth of 1.5 m. DC Geoelectrical and EM methods are used to see the fertility distribution on agricultural land.
Konsumsi mentimun (cucumis sativus linn) dalam menurunkan tekanan darah pada penderita hipertensi
Authors: Maharani Mahrunnisa Syahratudar , Maliya Arina 
Published: May 2024

Background: Hypertension is a degenerative disease that increases mortality and morbidity throughout the world. Among the problems that often affect the treatment of hypertensive patients are the side effects of pharmacological drugs. Among the side effects caused by taking pharmacological drugs are increased blood sugar levels, cholesterol and decreased energy.
Purpose: To prove the effect of giving cucumber juice on blood pressure values in hypertension sufferers.
Method: Quantitative research using a quasi-experimental method, non-randomized pre-test-post-test design with control group. Data were collected using a digital sphygmomanometer instrument, observation sheet, blood pressure values, and 50ml cucumber. The data analysis used was the Wilcoxon and Mann Whitney non-parametric statistical test
Results: This study describes that after seven days of intervention there was a significant reduction in the average systolic and diastolic blood pressure (20.68 ± 8.3) and (9.00 ± 5) with a p-value of 0.001 in systolic and diastolic blood pressure. The control group experienced a non-significant decrease in systolic pressure (0.66 ± 5.5) with a p-value of 0.317 and diastolic pressure (0.00 ± 0.0) with a p-value of 1.000.
Conclusion: Giving cucumber juice can reduce blood pressure values for hypertensive patients.

Keywords: Blood Pressure Values; Cucumber; Hypertension.

Pendahuluan: Hipertensi menjadi kasus degeneratif yang meningkatkan mortalitas dan morbiditas di semua dunia. Diantara persoalan yang kerap memberikan pengaruh pengobatan pasien hipertensi ialah efek samping obat farmakologis Diantara efek samping yang ada disebabkan mengonsumsi obat farmakologi ialah naiknya kadar gula darah, kolesterol, dan penurunan energi.
Tujuan: Untuk membuktikan pengaruh pemberian jus mentimun terhadap nilai tekanan darah pada penderita hipertensi.
Metode: Penelitian kuantitatif dengan menggunakan metode quasi eksperimental desain non- randomized pre-test-post-test with control group. Pengumpulan data menggunakan instrumen sphygmomanometer digital lembar observasi, nilai tekanan darah, dan mentimun 50ml. Analisis data yang digunakan ialah uji statistik non parametrik Wilcoxon dan Mann Whitney
Hasil: Penelitian ini mendeskripsikan sesudah tujuh hari pemberian intervensi terdapat penyusutan rata-rata tekanan darah sistolik dan diastolik yang signifikan (20.68±8.3) dan (9.00±5) dengan p-value 0.001 pada tekanan darah sistolik dan diastolik. Kelompok kontrol mengalami penurunan tekanan sistolik yang tidak signifikan (0.66±5.5) dengan p-value 0.317 dan tekanan diastolik (0.00±0.0) dengan nilai p-value 1.000.
Simpulan: Pemberian jus mentimun dapat memengaruhi penurunan nilai tekanan darah untuk pasien hipertensi.
Kata Kunci: Hipertensi; Mentimun; Nilai Tekanan Darah.
Perancangan Model Manajemen (Tata Kelola) Data Menggunakan Domain APO14 COBIT 2019
Authors: Prasetya Rendra , Alva Hendi Muhammad  , Asro Nasiri  
Published: May 2024

Manajemen data memainkan peran krusial dalam operasional organisasi, pentingnya manajemen (tata kelola) data yang tepat untuk mendukung operasional dan pengambilan keputusan yang cermat. COBIT 2019, terutama melalui domain APO14, memberikan kerangka kerja penting bagi organisasi dalam mengoptimalkan manajemen data mereka. Penelitian ini bertujuan untuk menganalisis penerapan COBIT 2019 dalam meningkatkan tata kelola di organisasi, dengan fokus pada Fakultas Syariah di IAIN Ponorogo sebagai studi kasus. Manajemen data yang baik tidak hanya mempengaruhi operasional internal organisasi tetapi juga dampaknya pada keputusan strategis, inovasi, dan daya saing di pasar. Pentingnya tata kelola data yang tepat tercermin dalam praktik seperti perencanaan, pengorganisasian, penyimpanan, dan pemanfaatan data secara cermat. Namun, masih ada tantangan dalam mengintegrasikan secara holistik di berbagai unit dalam organisasi, seperti yang terjadi di Fakultas Syariah IAIN Ponorogo. Dengan pencapaian nilai capability level tata kelola data sebesar 3,14 menurut domain APO14 COBIT 2019, Fakultas Syariah telah mencapai tingkat memadai dalam pengelolaan data. Meski demikian, terdapat kebutuhan untuk meningkatkan aspek-aspek tertentu dalam subdomain seperti APO14.02, APO14.03, APO14.04, APO14.06, APO14.07, APO14.08, APO14.09, dan APO14.10. Penelitian ini berkontribusi pada pemahaman dan pengembangan COBIT 2019, khususnya domain APO14 dalam konteks manajemen data, dan memberikan pandangan yang jelas serta rekomendasi praktis dalam meningkatkan tata kelola data organisasi.
Gut microbiota influence acute pancreatitis through inflammatory proteins: a Mendelian randomization analysis
Authors: Huang Peiyao , Liu Qiang , Zhang Tianlong , Yang Jianfeng 
Published: May 2024

Background/AimWe employed Mendelian randomization (MR) analysis to investigate the causal relationship between the gut microbiota, acute pancreatitis, and potential inflammatory proteins.MethodsThe data for gut microbiota, acute pancreatitis, and inflammatory proteins are sourced from public databases. We conducted a bidirectional MR analysis to explore the causal relationship between gut microbiota and acute pancreatitis, and employed a two-step MR analysis to identify potential mediating inflammatory proteins. IVW is the primary analysis method, heterogeneity, pleiotropy, and sensitivity analyses were also conducted simultaneously.ResultsWe identified five bacterial genera associated with the risk of acute pancreatitis, namely genus.Coprococcus3, genus.Eubacterium fissicatena group, genus.Erysipelotrichaceae UCG-003, genus.Fusicatenibacter, and genus.Ruminiclostridium6. Additionally, we have discovered three inflammatory proteins that are also associated with the occurrence of acute pancreatitis, namely interleukin-15 receptor subunit alpha (IL-15RA), monocyte chemoattractant protein-4 (CCL13), and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Following a two-step MR analysis, we ultimately identified IL-15RA as a potential intermediate factor, with a mediated effect of 0.018 (95% CI: 0.005 - 0.032).ConclusionOur results support the idea that genus.Coprococcus3 promotes the occurrence of acute pancreatitis through IL-15RA. Furthermore, there is a potential causal relationship between the gut microbiota, inflammatory proteins, and acute pancreatitis. These findings provide new insights for subsequent acute pancreatitis prevention.
Iodine nutritional status and its associations with thyroid function of pregnant women and neonatal TSH
Authors: Fan Lijun , Bu Ye , Chen Shiqi , Wang Sihan , Zhang Wei , He Yan , Sun Dianjun 
Published: May 2024

IntroductionIodine serves as a crucial precursor for the synthesis of thyroid hormones and plays an import role in both pregnant women and their offspring. The relationships between iodine nutritional status and maternal thyroid function and neonatal outcomes remain inconclusive in areas with adequate iodine nutrition. This study aims to investigate their correlations.MethodsBlood, morning urine and 24-hour urine were collected from the pregnant women to measure thyroid functions, serum iodine concentration (SIC), morning urine iodine concentration (UIC) and 24-hour urine iodine excretion (24-hour UIE). Indicators of their offspring’s neonatal indexes were recorded.ResultsA total of 559 pregnant women were enrolled in this study. The iodine indicators including Tg, 24-hour UIE and morning UIC were significantly different among the euthyroid pregnant women and those with different thyroid disorders. The levels of FT3, FT4, and SIC exhibited a gradual decline and the concentration of TSH exhibited a gradual increase trend throughout the progression of pregnancy in euthyroid pregnant women. There were no significant differences in neonatal outcomes and neonatal TSH values among euthyroid pregnant women and thyroid disorders pregnant women. SIC had a significant impact on maternal FT4 levels throughout all three trimesters, with varying degrees of importance observed in each trimester. TSH level emerged as the primary determinant of FT4 during the first trimester, while SIC exerted a predominant influence on FT4 levels in the second and third trimesters. The prevalence of thyroid disorders in pregnant women was the lowest when the SIC of pregnant women was probable in the range of 60~70 μg/L, 24-hours UIE was in the range of 250~450 μg, and Tg was in the range of 9~21 μg/L. Maternal TSH exhibited a notable influence on neonatal TSH levels, particularly at the 50th and 75th quantiles. Among the iodine nutritional indicators, SIC and morning UIC demonstrated higher AUC values for abnormal FT4 and TSH, respectively.DiscussionThe iodine nutrition status of pregnant women exerts an impact on their thyroid function and prevalence of thyroid disorders, and neonatal TSH was affected by maternal TSH. SIC may be a better indicator for iodine nutritional assessment than other indexes.
Long-term effects of different hypoglycemic drugs on carotid intima-media thickness progression: a systematic review and network meta-analysis
Authors: Lv Qianyu , Yang Yingtian , Lv Yanfei , Wu Qian , Hou Xinzheng , Li Lanlan , Ye Xuejiao , Yang Chenyan , Wang Shihan 
Published: May 2024

ObjectiveThe progression of carotid intima-media thickness (cIMT) can partially predict the occurrence of future cardiovascular events. This network meta-analysis compared the effects of 14 antidiabetic drugs (acarbose, alogliptin, exenatide, glibenclamide, glimepiride, ipragliflozin, metformin, nateglinide, pioglitazone, rosiglitazone, sitagliptin, tofoglifozin, troglitazone, voglibose) on the progression of cIMT.MethodPubMed, EMBASE, Cochrane Library, and Web of Science were searched to screen all clinical trials of treatment of cIMT with hypoglycemic agents before March 1, 2024. The differences in the changes in cIMT between the treatment group and control group were evaluated.ResultAfter screening 8395 citations, 25 studies (6675 patients) were included. The results indicated that exenatide had the best efficacy in slowing down cIMT progress, and exenatide [MD=-0.13,95%CI (-0.25, -0.01)], alogliptin [MD=-0.08,95%CI (-0.13, -0.02)] and metformin [MD=-0.05, 95%CI (-0.09, -0.02)] are more effective than placebo.ConclusionLong-term treatment of exenatide, alogliptin, and metformin may be more effective than other hypoglycemic drugs in slowing the progression of cIMT.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024519474.
Case report: Spontaneous rupture of leiomyosarcoma uteri 8 months after primary laparoscopic surgery of STUMP
Authors: Bicanin-Ilic Marija , Ilic Igor , Dimitrijevic Aleksandra , Mujkovic Srdjan , Jovic Nikola , Rakic Dejana , Arsenijevic Neda , Nikolic-Turnic Tamara , Balovic Goran , Peric Andjela , Mitrovic Aleksandra , Nikolov Aleksandar 
Published: May 2024

IntroductionLeiomyosarcoma (LMS), together with smooth muscle tumors of uncertain malignant potential (STUMP) and benign leiomyomas, belongs to a heterogeneous group of uterine neoplasms. According to the World Health Organization, tumors originating from uterine smooth muscle fibers are the second most frequent tumors. It is challenging to distinguish between STUMP and LMS because of an overlap of symptoms, lack of a precise definition, and unequivocal information obtained using imaging diagnostic methods. Following myomectomy or hysterectomy with laparoscopic or laparotomy surgery and a definitive histological diagnosis of STUMP, the course of treatment is determined by the need to preserve fertility. In 2014, the U.S. Food and Drug Administration published an alert that unprotected laparoscopic morcellation is correlated with a 3-fold higher likelihood of dissemination of malignant cells and disease progression. Unprotected morcellation was independently associated with a higher risk of disease recurrence after demolition or conservative surgery, with a relative risk of 2.94.ConclusionHematoperitoneum resulting from the spontaneous rupture of a uterine tumor is a rare gynecological emergency, with very few cases reported in the last decade.
The influence of cognitive load and vision variability on postural balance in adolescents with intellectual disabilities
Authors: Jouira Ghada , Alexe Dan Iulian , Moraru Cristina Elena , Rekik Ghazi , Alexe Cristina Ioana , Marinău Marius Alin , Sahli Sonia 
Published: May 2024

IntroductionThis study aimed to investigate the impact of cognitive load, particularly its escalation during the execution of the same test, under varying vision conditions, on postural balance among adolescents with intellectual disability (ID).MethodsTwenty adolescents underwent balance assessments under different visual conditions (Open Eyes (OE), Closed Eyes (CE), Flash, Goggles, Visual Stimulation (VS)) and task settings (Single Task (ST), Dual Task (DT) without challenges, and DT with challenges). The cognitive test was assessed using Verbal Fluency (VF).Results and discussionSignificant effects were found for Task (p &lt; 0.001, ηp2 = 0.85), indicating that CoP values significantly increased (p &lt; 0.05) with the introduction of the DT. Dual Task Cost (DTC) demonstrated significant effects for Vision (p = 0.008, ηp2 = 0.62), with values varying significantly (p &lt; 0.05) among different vision conditions, especially in CE and Flash conditions. Visual Dependency Quotient (VDQ) analyses revealed significant effects of condition (p &lt; 0.001, ηp2 = 0.84), with significant changes observed in CE/OE and Flash/OE conditions (p &lt; 0.05). Significant effects were observed for Cognitive performance in the Challenge condition (p &lt; 0.001, ηp2 = 0.86), with decreased performance with cognitive task challenges, particularly in Flash and Goggles conditions (p &lt; 0.05). In conclusion, cognitive tasks, especially challenging ones, and visual variations significantly impact postural balance in adolescents with ID.