bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facilitated Integrated Mood Management for adults with bipolar disorder
Authors: Miklowitz David J , Price Jonathan , Holmes Emily A , Rendell Jennifer , Bell Sarah , Budge Katie , Christensen Jean , Wallace Joshua , Simon Judit , Armstrong Neil M , McPeake Lily , Goodwin Guy M , Geddes John R 
Published: March 2012

Miklowitz DJ, Price J, Holmes EA, Rendell J, Bell S, Budge K, Christensen J, Wallace J, Simon J, Armstrong NM, McPeake L, Goodwin GM, Geddes JR. Facilitated Integrated Mood Management for adults with bipolar disorder.  Bipolar Disord 2012: 14: 185–197. © 2012 The Authors. Journal compilation © 2012 John Wiley & Sons A/S.Objectives:  We describe the development of a five‐session psychoeducational treatment, Facilitated Integrated Mood Management (FIMM), which contains many of the core elements of longer evidence‐based psychosocial treatments for bipolar disorder. FIMM incorporated a novel mood monitoring program based on mobile phone technology.Methods:  Adult patients with bipolar I and II disorders (N = 19) received six sessions (Pilot I: n = 14) or five sessions (Pilot II: n = 5) of FIMM with pharmacotherapy. Treatment facilitators were novice counselors who were trained in a three‐day workshop and supervised for six months. FIMM sessions focused on identifying early signs of recurrence, maintaining regular daily and nightly routines, rehearsing mood management strategies, maintaining adherence to medications, and education about substance abuse. Patients sent daily text messages or e‐mails containing ratings of their mood and sleep, and weekly messages containing self‐ratings on the Quick Inventory of Depressive Symptomatology (QIDS) and the Altman Self Rating Mania Scale (ASRM). Patients also completed a weekly mood management strategies questionnaire.Results:  Of the 19 patients, 17 (89.5%) completed FIMM in an average of 9.2 ± 3.4 weeks (Pilot I) and 7.6 ± 0.9 weeks (Pilot II). Patients reported stable moods on the QIDS and ASRM over a 120‐day period, and on average responded to 81% of the daily message prompts and 88% of the weekly QIDS and ASRM prompts. Facilitators maintained high levels of fidelity to the FIMM manual. Patients’ knowledge of mood management strategies increased significantly between the first and last weeks of treatment.Conclusions:  Patients with bipolar disorder can be engaged in a short program of facilitated mood management. The effects of FIMM on the course of bipolar disorder await evaluation in randomized trials. The program may be a useful adjunct to pharmacotherapy in community centers that cannot routinely administer full courses of psychosocial treatment.
Application of the ADVIA cerebrospinal fluid assay to count residual red blood cells in blood components
Authors: Culibrk B. , Stone E. , Levin E. , Weiss S. , Serrano K. , Devine D. V. 
Published: March 2012

Background and Objectives  There is no automated, accurate assay for the enumeration of residual red blood cells (rRBCs) in non‐RBC components for transfusion, despite the potential risk of allo‐immunization when mismatched components are transfused.Materials and Methods  The automated ADVIA 120 cerebrospinal fluid (CSF) assay, which is approved to count RBCs and WBCs in CSF samples, was optimized and tested to measure rRBC in platelet concentrate (PC) and plasma components.Results  Sample dilution, incubation time and reagent volume were optimized for use with non‐RBC blood products. The assay was linear (R2 = 0·99), even at low rRBCs counts. Intra‐ and inter‐assay variation gave coefficients of variance (CV) between 2·2 and 9·4% and 2·6 and 14·9%, respectively, depending on rRBC levels. Good correlation (r = 0·995) was found between the automated assay and manual counting, which is considered the gold standard. Using the automated assay, the range of rRBCs (count/unit) in buffy‐coat platelet concentrate (PCs) was 27–5505 × 106 and in apheresis PCs was 1–361 × 106.Conclusion  The ADVIA CSF assay is a sensitive, precise and accurate means to assess rRBC counts in non‐RBC components.
Genotypic Differences in Root Hair Deformation and Subsequent Nodulation for Red Clover under Different Additions of Starter N Fertilization
Authors: Thilakarathna R. M. M. S. , Papadopoulos Y. A. , Fillmore S. A. E. , Prithiviraj B. 
Published: March 2012

AbstractRed clover cultivars, including diploid and tetraploid, are commonly used in legume‐based pasture mixtures. However, information on nodulation under different starter N regimens is limited. We hypothesized that there is genetic variability among different red clover cultivars for nodulation. A root hair deformation assay was conducted using three diploid (AC Christie, Tapani and CRS15) and three tetraploid (Tempus, CRS18 and CRS39) red clover cultivars by inoculating them with Rhizobium leguminosarum biovar trifolii. Nodulation and morphological characteristics of two selected red clover cultivars, AC Christie and Tempus, were determined under five starter N concentrations (0, 0.2, 0.4, 0.8 and 1.6 mg per plant). Inoculation with rhizobia increased root hair deformation with significant interaction across cultivars. Nodulation was delayed under high starter N concentrations, and genotypic differences were evident for days‐to‐nodule initiation. There was a positive quadratic response to starter N for AC Christie and a negative quadratic response for Tempus for nodulation. Tempus had more active nodules (92 %) than AC Christie (73 %). The genetic variability of red clover cultivars should be considered in N fixation studies and their response to availability of initial N.
Functional analysis of inter‐individual transcriptome differential expression in pig longissimus muscle
Authors: Zhao S. , Hulsegge B. , Harders F.L. , Bossers R. , Keuning E. , Hoekman A.J.W. , Hoving‐Bolink R. , te Pas M.F.W. 
Published: March 2012

SummarySelection of pigs for increased meat production or improved meat quality changes muscle mass and muscle composition. This will be related to transcriptome expression profile changes in muscle tissue, generating inter‐individual differences. This study investigated the differentially expressed genes in the transcriptome profiles of the longissimus muscle of 75 Large White–Duroc cross sows and castrates. The use of a common reference design enabled to investigate the inter‐individual transcriptome expression profile differences between the animals as compared with the means of all animals. The aim of the study was to identify the biological processes related to these inter‐individual differences. It was expected that these processes underlie the selection effects. In total, 908 transcripts were differentially expressed. Among them, 762 were mainly downregulated and 146 were mainly upregulated. Gene Ontology and Pathways analyses indicated that the differentially expressed genes belong to three groups of processes involved in protein synthesis and amino acid–protein metabolism, energy metabolism and muscle‐specific structure and activity processes. Comparing the functional biological analysis results with previously reported data suggested that the protein synthesis, energy metabolism and muscle‐specific structure would contribute to meat production and the meat quality.
Rainforest and savanna landscape dynamics in New Caledonia: Towards a mosaic of stable rainforest and savanna states?
Authors: IBANEZ THOMAS , BORGNIET LAURENT , MANGEAS MORGAN , GAUCHEREL CEDRIC , GÉRAUX HUBERT , HÉLY CHRISTELLE 
Published: March 2012

AbstractStable forested environments can be converted to savanna in response to changes in environmental disturbances. New Caledonia is a biodiversity hotspot; significant ecological and economic resources would be lost if forests were turned into savanna by anthropogenic environmental changes. On the landscape scale, systems that have undergone shifts of this kind are characterized by sharp forest–savanna boundaries and mosaic‐like distributions of savanna and forest. Understanding the locations and the dynamics of such boundaries is a challenge for ecologists and is critical for landscape management and biodiversity conservation. Using a time series of aerial photographs (1955–2000) and a forest habitat suitability map, we tested the hypothesis that topography and spatial processes, especially those relating to fire spread and seed dispersal, are the main determinants of the spatial distribution of rainforest and savanna in a New Caledonian landscape covering 24 km2. Within the studied landscape, the overall forest coverage decreased by 24% between 1976 and 2000. This was primarily due to the contraction of forests on west‐facing slopes, which accounted for about 90% of the total loss. Conversely, the east‐facing forests seemed to have contracted extensively prior to the studied period, and were confined to refuges. A habitat suitability index calculated from the landscape's topographical features using generalized additive models accurately predicted both the presence of forests and the probability of forest expansion/contraction. We also provide evidence that spatial processes such as fire spread and seed dispersal limit the expansion and contraction of forests. Our results suggest that rainforests on west‐facing slopes in New Caledonia will be progressively destroyed by fire until they are restricted to refuges along thalwegs and creeks, as appears to have already happened for their east‐facing counterparts.
Effects of Works Councils on Firm‐Provided Further Training in Germany
Authors: Stegmaier Jens 
Published: March 2012

AbstractUnions are an important indicator of various measures of firm performance in Anglo‐Saxon countries. The same is true for the German analogue of the workplace union, the works council. Using German establishment data, I examine the impact of works councils on further training. I employ pooled logit and count‐data models to analyse the further training activity and intensity of German firms. Because the treatment variable may suffer from endogeneity, I also adopt linear and nonlinear instrumental variable techniques. The analysis reveals a positive impact of works councils on firm‐provided training and provides slightly weaker evidence for firm‐size differentials in workplace representation. I conclude that enhanced management–employee relations foster the training efforts of firms.
The Views of Members towards Workplace Union Organization in Banking between 1999 and 2008
Authors: Waddington Jeremy 
Published: March 2012

AbstractIn tracing the changing perceptions of members in banking of trade union workplace organization between 1999 and 2008, this article illustrates a pattern of decline in terms of the coverage and performance of workplace organization. Contrary to the claims made by proponents of partnership arrangements, merger involvement and organizing, these strategies were not sufficient to arrest the decline in workplace organization. In consequence, members remained reliant on trade union full‐time officers for support.
Vignettes and Health Systems Responsiveness in Cross-Country Comparative Analyses
Authors: Rice Nigel , Robone Silvana , Smith Peter C. 
Published: March 2012

SummaryThe paper explores the use of anchoring vignettes as a means to adjust survey reports of health system performance for differential reporting behaviour by using data contained within the World Health Survey. Survey respondents are asked to rate their experiences of health systems across a number of domains on a five-point categorical scale. Using data provided through a set of vignettes we investigate variations in reporting of interactions with health services across both sociodemographic groups and countries. We show how the method of anchoring vignettes can be used to enhance cross-country comparability of performance. Our results show large changes in the rankings of country performance once adjustment for systematic country level reporting behaviour has been undertaken compared with a ranking based on raw unadjusted data.
Quantifying the Weight of Evidence from a Forensic Fingerprint Comparison: A New Paradigm
Authors: Neumann C. , Evett I. W. , Skerrett J. 
Published: March 2012

SummaryThe fingerprint has, with considerable justification, come to be regarded as the acme of forensic identification. Over the last century, millions of cases have been resolved world wide because of marks left at crime scenes. The comparison methodology has not evolved greatly during its history and it is universal practice to present fingerprint evidence to a court as a categoric opinion of identification or exclusion, or to classify the evidence as inconclusive and not to report it. There has been a growing movement to supplement the fingerprint examination process by one that has a statistical model, supported by appropriate databases for calculating numerical measures of weight of evidence. The movement calls for the establishment of a logical framework for informing conclusions, based on explicit assumptions and data and open to revision and improvement. The aim is to enable the numerical evaluation of evidence that would currently be reported as a categorical identification and also of evidence that would currently be classified as inconclusive. The paper presents the results of a project carried out by the Forensic Science Service that aims to attain this goal. After a historical review, we describe a formal model for assigning numerical values to configurations of minutiae in fingerprints. We describe how the parameters of the model have been optimized to take account of interoperator variability and distortion of the finger pad, and we present the results of a substantial validation experiment that was based on searches that have been carried out on the US national fingerprint database of approximately 600 million fingerprints.
Color vision: a study of essential tremor cases versus normal controls
Authors: Louis E. D. , Gerbin M. , Viner A. S. 
Published: March 2012

Background and purpose:  Patients with essential tremor (ET) and Parkinson’s disease (PD) may exhibit overlapping clinical features. Also, a growing number of non‐motor features are being documented in ET. Color vision abnormalities, although well known to occur in PD, have not been studied extensively in ET. We assessed color vision in ET cases and controls. We furthermore assessed subgroups of ET cases with clinical features that might link them to PD (i.e., ET cases with a family history of PD, and ET cases with rest tremor) to determine whether these cases had greater color vision abnormalities than ET cases without those features.Methods:  Participants were enrolled in a case–control study at Columbia University Medical Center. Color discrimination testing was performed using the Farnsworth–Munsell 100 Hue test. The total error score (TES) for the hue test was determined.Results:  The TES was similar in 55 ET cases and 55 controls (144.6 ± 91.8 vs. 145.6 ± 96.6, P = 0.96). ET cases with rest tremor (n = 8) were similar to ET cases without rest tremor (n = 47) with respect to the TES (117.0 ± 73.4 vs. 149.3 ± 94.4, P = 0.36), as were ET cases with a family history of PD (n = 9) versus without (n = 46) (144.4 ± 57.0 vs. 144.6 ± 97.6, P = 0.996).Conclusions:  Although a number of links exist between ET and PD, and non‐motor features have been described in both, a color vision abnormality does not seem to be a feature of ET.
The mid‐M1 segment of the middle cerebral artery is a cutoff clot location for good outcome in intravenous thrombolysis
Authors: Saarinen J. T. , Sillanpää N. , Rusanen H. , Hakomäki J. , Huhtala H. , Lähteelä A. , Dastidar P. , Soimakallio S. , Elovaara I. 
Published: March 2012

Background and purpose:  We studied the impact of the location of the thrombus (internal carotid artery, proximal M1 segment, distal M1 segment, M2 segment, and M3 segment of the middle cerebral artery) in predicting the clinical outcome of patients treated with intravenous thrombolytic therapy (<3 h) in a retrospective cohort.Methods:  Anterior circulation thrombus was detected with computed tomography angiography in 105 patients. Baseline clinical and radiological information was collected and entered into logistic regression analysis to predict favorable clinical outcome (3‐month modified Rankin Scale from 0 to 2 was a primary outcome measure).Results:  Three months after stroke, there was a significant increase in mortality (32% vs. 3%, P < 0.001) and functional dependency (82% vs. 29%, P < 0.001) in patients with internal carotid artery or proximal M1 segment of the middle cerebral artery thrombus compared to a more distal occlusion. In the regression analysis, after adjusting for National Institutes of Health Stroke Scale, age, sex, and onset‐to‐treatment time, the clot location was an independent predictor of good clinical outcome (P = 0.001) and exhibited dose‐response type behavior when moving from a proximal vessel position to a more distal one. When the location was dichotomized, a cutoff between the proximal and the distal M1 segments best differentiated between good and poor clinical outcome (OR = 16.0, 95% CI 3.9–66.2).Conclusions:  The outcome of acute internal carotid artery or proximal M1 segment of the middle cerebral artery occlusion is generally poor even if treated with intravenous thrombolysis. Alternative revascularization strategies should be considered. Vascular imaging at the admission is required to guide this decision.
Use of ring recoveries to predict habitat suitability in small passerines
Authors: Tellería José Luis , Santos Tomás , Refoyo Pablo , Muñoz Jesús 
Published: March 2012

AbstractAim  Abundance of small passerines may be distributed over large wintering areas according to geographical patterns that are difficult to detect. This may prevent the identification and conservation of the most suitable sectors, or the detection of local and regional features affecting the species during winter. In this paper, we explore the usefulness of ring recoveries to predict bird distribution in wintering grounds by using Maxent, one of the presence‐only techniques available for modelling species distributions. We test whether suitability indices obtained in 2.5 × 2.5 km UTM squares from ring recoveries were positively correlated with the actual abundance of robins (Erithacus rubecula) and blackcaps (Sylvia atricapilla) inside the squares.Location  Spain.Methods  We used 686 and 1139 localities across the country in which blackcap and robin ring recoveries were recorded by the Spanish Office of Migratory Species to generate the suitability maps. In addition, we sampled bird abundance inside 70 control squares independent of ring recovery localities along a belt crossing mountains, highlands and lowlands of the Iberian Peninsula during January from 2006 to 2011.Results  Suitability indices predicted by Maxent were positively correlated with robin (r = 0.42, n = 70, P < 0.001) and blackcap (r = 0.52, n = 70, P < 0.001) abundances in the 70 control squares along the belt crossing the Iberian Peninsula.Main conclusions  These results suggest that the use of distribution models with ring recoveries may be used to describe the habitat suitability of the winter ranges of small, common passerines. This also means that the huge number of ring recoveries stored in national and transnational data banks could be used to explore the factors shaping bird ranges and to forecast the geographical distribution of suitable wintering areas of migratory birds in large, poorly known regions. This may be useful in biogeography and conservation.
Impaired memory and executive function associated with decreased medial temporal and prefrontal blood flow in Clinical Dementia Rating 0.5 status: the Osaki‐Tajiri project
Authors: INOUE Kentaro , MEGURO Kenichi , AKANUMA Kyoko , MEGURO Mitsue , YAMAGUCHI Satoshi , FUKUDA Hiroshi 
Published: March 2012

AbstractAim:  The Clinical Dementia Rating (CDR) is an assessment of dementia severity based on observations of activities of daily living, and a CDR of 0.5 (CDR 0.5) represents questionable dementia. A combination of the Cognitive Abilities Screening Instrument (CASI) and the Trail Making Test (TMT) scores discriminated CDR 0.5 subjects from healthy participants with a high degree of accuracy. We investigated the neurological background of CDR 0.5 subjects by correlating CASI and TMT scores with regional cerebral blood flow (rCBF) as measured by single photon emission computed tomography (SPECT).Methods:  From a community‐based cohort, 22 CDR 0.5 participants were recruited. CASI and TMT scores, rCBF measure using [123I]‐N‐isopropyl‐p‐iodoamphetamine and SPECT were obtained. We evaluated the relationships between the CASI domain scores, between TMT scores and rCBF in a regions‐of‐interest‐based analysis, and voxel‐based analysis using Statistical Parametric Mapping 5 software.Results:  We found that lower rCBF in the left medial temporal cortex correlated with a decreased CASI domain recent memory score both in the regions‐of‐interest and statistical parametric mapping analysis. In both the regions‐of‐interest and statistical parametric mapping analysis, the rCBF in the left prefrontal cortex correlated with CASI domain remote memory and mental manipulation and concentration.Conclusions:  Our results indicate that some CDR 0.5 subjects have functional impairments in the medial temporal lobe as well as in the prefrontal cortex, as reflected in the cognitive decline measured by CASI and TMT.
Evaluation of dementia‐prevention classes for community‐dwelling older adults with mild cognitive impairment
Authors: ITO Yasuyo , URAKAMI Katsuya 
Published: March 2012

AbstractAim:  The number of elderly people with dementia in Japan is likely to increase as the population ages. In some areas in Tottori Prefecture, dementia‐prevention classes have been conducted for several years. In the present study, we evaluated dementia‐prevention classes in nine districts of Tottori Prefecture in terms of cognitive function, assessment by the leader and subjective evaluation by participants.Methods:  The study's subjects included 112 community‐dwelling elderly residents who were selected after a two‐step screening. Data were collected according to the following four factors: (i) evaluation of cognitive function at the beginning and end of classes; (ii) the content of the classes; (iii) observations regarding the state of subjects; and (iv) participants' subjective evaluation obtained via a questionnaire distributed at the final class.Results:  In terms of cognitive function among all subjects, scores significantly improved after the dementia‐prevention classes. However, there were no significant cognitive improvements in the districts where programmes were biased towards a single category (e.g. systemic exercise, creative activities). Based on class leaders' assessments, subjects showed improved appearance and facial expression in later classes. Participants became more involved in the programmes, and their interests in others increased. In terms of their daily lives, subjects became more involved with others and more active after participating in the classes.Conclusions:  Dementia‐prevention classes improved not only cognitive function but also other aspects of daily life, as well. We thought it was important to evaluate both objective and subjective factors related to the classes.