bluuebunny/crossref_metadata_2025_split huggingface dataset:
Binocularly suppressed stimuli induce brain activities related to aesthetic emotions
Authors: Hoshi Hideyuki , Ishii Akira , Shigihara Yoshihito , Yoshikawa Takahiro 
Published: May 2024

IntroductionAesthetic emotions are a class of emotions aroused by evaluating aesthetically appealing objects or events. While evolutionary aesthetics suggests the adaptive roles of these emotions, empirical assessments are lacking. Previous neuroscientific studies have demonstrated that visual stimuli carrying evolutionarily important information induce neural responses even when presented non-consciously. To examine the evolutionary importance of aesthetic emotions, we conducted a neuroscientific study using magnetoencephalography (MEG) to measure induced neural responses to non-consciously presented portrait paintings categorised as biological and non-biological and examined associations between the induced responses and aesthetic ratings.MethodsMEG and pre-rating data were collected from 23 participants. The pre-rating included visual analogue scales for object saliency, facial saliency, liking, and beauty scores, in addition to ‘biologi-ness,’ which was used for subcategorising stimuli into biological and non-biological. The stimuli were presented non-consciously using a continuous flash suppression paradigm or consciously using binocular presentation without flashing masks, while dichotomic behavioural responses were obtained (beauty or non-beauty). Time-frequency decomposed MEG data were used for correlation analysis with pre-rating scores for each category.ResultsBehavioural data revealed that saliency scores of non-consciously presented stimuli influenced dichotomic responses (beauty or non-beauty). MEG data showed that non-consciously presented portrait paintings induced spatiotemporally distributed low-frequency brain activities associated with aesthetic ratings, which were distinct between the biological and non-biological categories and conscious and non-conscious conditions.ConclusionAesthetic emotion holds evolutionary significance for humans. Neural pathways are sensitive to visual images that arouse aesthetic emotion in distinct ways for biological and non-biological categories, which are further influenced by consciousness. These differences likely reflect the diversity in mechanisms of aesthetic processing, such as processing fluency, active elaboration, and predictive processing. The aesthetic processing of non-conscious stimuli appears to be characterised by fluency-driven affective processing, while top-down regulatory processes are suppressed. This study provides the first empirical evidence supporting the evolutionary significance of aesthetic processing.
Amino acid metabolomics and machine learning for assessment of post-hepatectomy liver regeneration
Authors: Yan Yuqing , Chen Qianping , Dai Xiaoming , Xiang Zhiqiang , Long Zhangtao , Wu Yachen , Jiang Hui , Zou Jianjun , Wang Mu , Zhu Zhu 
Published: May 2024

ObjectiveAmino acid (AA) metabolism plays a vital role in liver regeneration. However, its measuring utility for post-hepatectomy liver regeneration under different conditions remains unclear. We aimed to combine machine learning (ML) models with AA metabolomics to assess liver regeneration in health and non-alcoholic steatohepatitis (NASH).MethodsThe liver index (liver weight/body weight) was calculated following 70% hepatectomy in healthy and NASH mice. The serum levels of 39 amino acids were measured using ultra-high performance liquid chromatography–tandem mass spectrometry analysis. We used orthogonal partial least squares discriminant analysis to determine differential AAs and disturbed metabolic pathways during liver regeneration. The SHapley Additive exPlanations algorithm was performed to identify potential AA signatures, and five ML models including least absolute shrinkage and selection operator, random forest, K-nearest neighbor (KNN), support vector regression, and extreme gradient boosting were utilized to assess the liver index.ResultsEleven and twenty-two differential AAs were identified in the healthy and NASH groups, respectively. Among these metabolites, arginine and proline metabolism were commonly disturbed metabolic pathways related to liver regeneration in both groups. Five AA signatures were identified, including hydroxylysine, L-serine, 3-methylhistidine, L-tyrosine, and homocitrulline in healthy group, and L-arginine, 2-aminobutyric acid, sarcosine, beta-alanine, and L-cysteine in NASH group. The KNN model demonstrated the best evaluation performance with mean absolute error, root mean square error, and coefficient of determination values of 0.0037, 0.0047, 0.79 and 0.0028, 0.0034, 0.71 for the healthy and NASH groups, respectively.ConclusionThe KNN model based on five AA signatures performed best, which suggests that it may be a valuable tool for assessing post-hepatectomy liver regeneration in health and NASH.
Stem elongation and gibberellin response to submergence depth in clonal plant Alternanthera philoxeroides
Authors: Jing Shufang , Ren Xinyi , Lin Feng , Niu Hangang , Ayi Qiaoli , Wan Binna , Zeng Bo , Zhang Xiaoping 
Published: May 2024

Clonal plants are widely distributed in the riparian zone and play a very important role in the maintenance of wetland ecosystem function. Flooding is an environmental stress for plants in the riparian zone, and the response of plants varies according to the depth and duration of flooding. However, there is a lack of research on the growth response of clonal plants during flooding, and the endogenous hormone response mechanism of clonal plants is still unclear. In the present study, Alternanthera philoxeroides, a clonal plant in the riparian zone, was used to investigate the time-dependent stem elongation, the elongation of different part of the immature internodes, and the relationship between growth elongation and the phytohormone gibberellin (GA) under a series of submergence depths (0 m, 2 m, 5 m, and 9 m). The results showed that stem elongation occurred under all treatments, however, compared to 0 m (control), plants grew more under 2 m and 5 m submergence depth, while grew less under 9 m water depth. Additionally, basal part elongation of the immature internode was the predominant factor contributing to the stem growth of A. philoxeroides under different submergence depths. The phytohormone contents in basal part of the mature and immature internodes showed that GA induced the differential elongation of internode. Plant submerged at depth of 2 m had the highest GA accumulation, but plant submerged at depth of 9 m had the lowest GA concentration. These data suggested that GA biosynthesis are essential for stem elongation in A. philoxeroides, and the basal part of the immature internode was the main position of the GA biosynthesis. This study provided new information about the rapid growth and invasion of the clonal plant A. philoxeroides around the world, further clarified the effects of submergence depth and duration on the elongation of the stem, and deepened our understanding of the growth response of terrestrial plants in deeply flooded environments.
Analysis of writing in personality disorders in prison population
Authors: Muñoz-López Lucas , Fernández-García-Valdecasas Borja , López-Rodríguez Slava , Sánchez-Barrera María Blanca 
Published: May 2024

AbstractWriting involves the activation of different processing modes than reading comprehension, and therefore the level of activation varies depending on the moment and the task.Objectivesto analyze the profiles in terms of the proposed coding from the PROESC in terms of personality disorders [Antisocial Personality Disorder (ASPD) with drugs possession and consumption crimes (DPCC) and Obsessive-Compulsive Personality Disorder (OCPD)] with gender violence crimes (GVC) in the prisoners.DesignThe sample was composed of 194 men. The participants were divided into two groups. Group 1 (ASPD; DPCC) consisted of 81 men, and Group 2 (OCPD; GVC) consisted of 113 men.Main outcome measuresThey completed the Demographic, Offense, and Behavioral Interview in Institutions, the International Personality Disorders Examination (IPDE), and Writing Processes Evaluation Battery (PROESC).ResultsGroup 2 made more mistake than Group 1 in narratives tasks.ConclusionParticipants know phoneme-grapheme correspondence rules, language disturbances of a reiterative and persistent nature may appear in those who show compulsive behavior.
Utilizing portable electroencephalography to screen for pathology of Alzheimer’s disease: a methodological advancement in diagnosis of neurodegenerative diseases
Authors: Hata Masahiro , Miyazaki Yuki , Mori Kohji , Yoshiyama Kenji , Akamine Shoshin , Kanemoto Hideki , Gotoh Shiho , Omori Hisaki , Hirashima Atsuya , Satake Yuto , Suehiro Takashi , Takahashi Shun , Ikeda Manabu 
Published: May 2024

BackgroundThe current biomarker-supported diagnosis of Alzheimer’s disease (AD) is hindered by invasiveness and cost issues. This study aimed to address these challenges by utilizing portable electroencephalography (EEG). We propose a novel, non-invasive, and cost-effective method for identifying AD, using a sample of patients with biomarker-verified AD, to facilitate early and accessible disease screening.MethodsThis study included 35 patients with biomarker-verified AD, confirmed via cerebrospinal fluid sampling, and 35 age- and sex-balanced healthy volunteers (HVs). All participants underwent portable EEG recordings, focusing on 2-minute resting-state EEG epochs with closed eyes state. EEG recordings were transformed into scalogram images, which were analyzed using “vision Transformer(ViT),” a cutting-edge deep learning model, to differentiate patients from HVs.ResultsThe application of ViT to the scalogram images derived from portable EEG data demonstrated a significant capability to distinguish between patients with biomarker-verified AD and HVs. The method achieved an accuracy of 73%, with an area under the receiver operating characteristic curve of 0.80, indicating robust performance in identifying AD pathology using neurophysiological measures.ConclusionsOur findings highlight the potential of portable EEG combined with advanced deep learning techniques as a transformative tool for screening of biomarker-verified AD. This study not only contributes to the neurophysiological understanding of AD but also opens new avenues for the development of accessible and non-invasive diagnostic methods. The proposed approach paves the way for future clinical applications, offering a promising solution to the limitations of advanced diagnostic practices for dementia.
Assessment of knowledge, attitudes, and practices regarding cardiovascular diseases (CVDs) among older individuals of rural Bangladesh: findings from a face-to-face interview
Authors: Siddique Abu Bakkar , Hosen Md. Shohag , Akter Hasna , Hossain Syed Mujakkir , Al Mamun Md. 
Published: May 2024

IntroductionCardiovascular diseases (CVDs) stand as the foremost contributor to global mortality, claiming roughly 17.9 million lives each year, constituting 32.1% of total fatalities. Their impact is notably profound in economies such as Bangladesh, exacting a substantial economic burden. Consequently, grasping the landscape of knowledge, attitudes, and practices is essential for timely identification and prevention strategies.MethodsThis cross-sectional study, carried out between January and May 2023 in the rural regions of Zirani, Savar Upazila, Dhaka, Bangladesh, utilized convenient sampling and conducted face-to-face interviews using a semi-structured questionnaire. It encompassed socio-demographic factors, as well as knowledge, attitudes, and practices concerning CVDs. Data analysis employed descriptive statistics, chi-square tests, and regression analyses, utilizing both the R programming language and SPSS (Version 26).ResultA total of 424 participants aged 60 years and above were included. The majority were male (60.8%), and the mean age was 71.21 ± 9.21 years, 57.3% were between 60 and 70 years old. Factors such as education, monthly family income, high blood pressure, diabetes, and non-smoking. Were significantly associated with higher knowledge, attitudes and practices scores.ConclusionThis study illuminates CVD-related KAP among rural Older Individuals in Bangladesh, revealing significant associations between factors such as education, monthly family income, high blood pressure, and non-smoking, with higher scores in knowledge, attitudes, and practices regarding cardiovascular health. These insights underscore the importance of addressing socio-economic factors and health behaviors in developing targeted interventions for the prevention and management of cardiovascular diseases in this demographic.
Boredom and its perceived impact in adolescents with exceptional mathematical talent: a sequential mixed-methods study in Paraguay
Authors: Vuyk Alexandra , Montania Maureen , Barrios Liz 
Published: May 2024

IntroductionBoredom, a state where the task at hand presents difficulties in attentional resources and attributed meaning, can be detrimental to talent development by reducing cognitive engagement. This study employed a mixed sequential design to assess boredom in adolescents with exceptional mathematical talent in Paraguay participating in a talent development program.MethodsFirst, in the quantitative phase 54 students completed the Boredom Short Scale, School Attitudes Assessment Survey-Revised, and Psychological Well-Being Scale for Adolescents. Next, in the qualitative phase 50 students participated in focus groups to explore their personal experiences of boredom, along with their perception of possible factors that impact boredom.ResultsBoredom in this population was similar to the general population of adolescents, albeit significant differences existed in items and subscales showing a pattern unique to this population; they tended to become bored quicker but had an easier time sparking interest in activities. Higher boredom had small to moderate correlations with worse attitudes at school and with teachers, lower motivation and self-regulation in academic activities, lower self-control, and lower involvement in personal projects. Higher valuation of goals and academic self-perception related with a lower tendency toward boredom only in the context of a talent development program, but not at school. Boredom seemed multifaceted, with dimensions such as the absence of meaning, superficial entertainment, and wasted time. Contributing factors included waiting for other people’s slower pace, limited choices, lack of novelty, insufficient intellectual challenge, and the influence of teachers and social dynamics. Coping mechanisms included inner intellectual stimulation, seeking entertainment and escape, pursuing independent learning, extracurricular activities, like-minded peers, and extreme sensation-seeking.DiscussionFostering adequate challenge and support in advanced academic endeavors for the development of mathematical talent can prevent negative consequences associated with boredom in exceptionally talented populations.
Large Splenic Cyst: a Case Report
Authors: Каленчиц Т.И. , Кабак С.Л. , Сяхович С.В. , Примак С.В. 
Published: May 2024

В статье описан клинический случай диагностики бессимптомной кисты селезенки больших размеров у 44-летнего пациента терапевтического отделения с внегоспитальной пневмонией. По данным компьютерной томографии размеры кисты составляли 173×242×261 мм. Наряду с кистой селезенки были выявлены кистозные образования в головке и хвосте поджелудочной железы. Анатомическая близость хвоста поджелудочной железы и ворот селезенки создает возможность прямой экспансии панкреатической псевдокисты или попадания секрета поджелудочной железы в паренхиму селезенки. В последующем в хирургическом отделении из кисты было аспирировано 2 литра лизированной крови с нитями фибрина.
In this case report, a splenic cyst in a 44-year-old male with community-acquired pneumonia is presented. CT scan measurements of cyst were found to be 173×242×261 mm. Along with the splenic cyst, pancreatic pseudocysts were identified in the head and tail of the pancreas. The anatomical proximity of the tail of the pancreas to the hilum of the spleen creates the possibility of direct expansion of the pancreatic pseudocyst or entry of pancreatic secretions into the splenic parenchyma. Subsequently, in the surgical department, 2 liters of lysed blood with fibrin threads were aspirated from the cyst.
Studying the Component Composition of the Body at the Early Stage of Non-Alcoholic Fatty Liver Disease
Authors: Агабабян И.Р. , Хохлачева Д.С. , Ким Г.С. , Хохлачева Н.А. 
Published: May 2024

Обследовано 63 пациента с неалкогольной жировой болезнью печени на стадии стеатоза. В верификации диагноза помимо общеклинических данных использованы результаты ультразвукового исследования печени, определение печеночных ферментов в сыворотке крови. Оценка липидного обмена проводилась по содержанию в плазме крови общего холестерина, липопротеинов низкой плотности, липопротеинов высокой плотности, триглицеридов. Для изучения количества жировой (общий и висцеральный жир) и мышечной массы в организме всем пациентам проведена биоимпедансометрия. У обследуемых пациентов выявлены достоверные изменения липидного спектра крови в сторону увеличения общего холестерина, липопротеинов низкой плотности и триглицеридов, а уровень липопротеинов высокой плотности уменьшается. При анализе данных биоимпедансометрии отмечены достоверное повышение количества общего и висцерального жира, а также тенденция к снижению мышечной массы. Установлено, что развитие НАЖБП статистически значимо связано с увеличением количества жировой ткани (общего и висцерального жира) и с уменьшением мышечной массы, ассоциированными с дислипидемией. Увеличение количества жировой ткани, в том числе за счет висцерального жира, и уменьшение мышечной массы рассматриваются как факторы риска в развитии НАЖБП.
63 patients with non-alcoholic fatty liver disease at the steatosis stage were examined. To verify the diagnosis, in addition to general clinical data, the results of an ultrasound examination of the liver and determination of liver enzymes in the blood serum were used. Lipid metabolism was assessed by the content of total cholesterol, low-density lipoproteins, high-density lipoproteins, and triglycerides in the blood plasma. To study the amount of fat (total and visceral fat) and muscle mass in the body, all patients underwent bioimpedance measurements. The examined patients revealed significant changes in the blood lipid spectrum towards an increase in total cholesterol, low-density lipoproteins and triglycerides, and a decrease in the level of high-density lipoproteins. When analyzing bioimpedansometry data, a significant increase in the amount of total and visceral fat was noted, as well as a tendency towards a decrease in muscle mass. It has been established that the development of NAFLD is statistically significantly associated with an increase in the amount of adipose tissue (total and visceral fat) and a decrease in muscle mass associated with dyslipidemia. An increase in the amount of adipose tissue, including due to visceral fat, and a decrease in muscle mass are considered risk factors for the development of NAFLD.
PARTO HUMANIZADO: UMA REVISÃO BIBLIOMÉTRICA NA BASE DE DADOS BRASILEIRA
Authors: Rebouças Felipe Modesto Almeida , Lima Gabriel Lucena de , Silva Jessyca Evilly Nunes da , Medeiros Lívia Araújo Dantas de , Pereira Morgana Guadalupe Silva , Sousa Milena Nunes Alves de 
Published: May 2024

Introdução: Nos últimos vinte anos vem surgindo um aumento na quantidade de publicações sobre o tema “Parto Humanizado”, o que surge em conjuntura com o aumento de denúncias por violência obstétrica. Objetivo: Verificar o perfil das publicações sobre a temática “Parto Humanizado” na Scientific Electronic Library Online (SciELO). Método: Esta pesquisa foi uma revisão bibliométrica realizada na base de dados SciELO, sendo estruturada levando em conta três leis da bibliometria sobre a conduta da literatura, seguida de 5 etapas que estão em conformidade com o preconizado por Chueke e Amatucci (2022). Resultados: O tópico mais abordado nesses artigos foi "Humanização do parto e nascimento"(56%, n=14), seguido por "Percepções e experiências de mulheres e profissionais de saúde"(36%, n=9). Em terceiro lugar "Práticas obstétricas e assistenciais"(20%, n=5) , seguido por "Impacto das práticas no bem-estar materno e neonatal"(12%,n=3) e "violência Institucional e tensões na assistência obstétrica"(8%,n=2). Conclusão: Por meio dessa revisão bibliométrica observou-se que mesmo com o crescente interesse nessa nova área da medicina ainda pode-se observar como a abordagem para o acolhimento e o prognósticos para o trabalho de cuidado para com a mulher grávida é um elemento de suma importância para a construção de uma nova fase na medicina baseada em evidências, assim como humanizar procedimentos tão invasivos e mecanizados que dominam o universo da maternidade.
Planet Formation by Gas-assisted Accretion of Small Solids
Authors: D’Angelo Gennaro , Bodenheimer Peter 
Published: May 2024

Abstract
We compute the accretion efficiency of small solids, with radii 1 cm ≤ R

s
≤ 10 m, on planets embedded in gaseous disks. Planets have masses 3 ≤ M

p
≤ 20 Earth masses (M
⊕) and orbit within 10 au of a solar mass star. Disk thermodynamics is modeled via 3D radiation-hydrodynamics calculations that typically resolve the planetary envelopes. Both icy and rocky solids are considered, explicitly modeling their thermodynamic evolution. The maximum efficiencies of 1 ≤ R

s
≤ 100 cm particles are generally ≲10%, whereas 10 m solids tend to accrete efficiently or be segregated beyond the planet’s orbit. A simplified approach is applied to compute the accretion efficiency of small cores, with masses M

p
≤ 1 M
⊕ and without envelopes, for which efficiencies are approximately proportional to

M

p

2

/

3

. The mass flux of solids, estimated from unperturbed drag-induced drift velocities, provides typical accretion rates dM

p
/dt ≲ 10−5
M
⊕ yr−1. In representative disk models with an initial gas-to-dust mass ratio of 70–100 and total mass of 0.05–0.06 M
⊙, the solids’ accretion falls below 10−6
M
⊕ yr−1 after 1–1.5 Myr. The derived accretion rates, as functions of time and planet mass, are applied to formation calculations that compute dust opacity self-consistently with the delivery of solids to the envelope. Assuming dust-to-solid coagulation times of ≈0.3 Myr and disk lifetimes of ≈3.5 Myr, heavy-element inventories in the range 3–7 M
⊕ require that ≈90–150 M
⊕ of solids cross the planet’s orbit. The formation calculations encompass a variety of outcomes, from planets a few times M
⊕, predominantly composed of heavy elements, to giant planets. The peak luminosities during the epoch of the solids’ accretion range from ≈10−7 to ≈10−6
L
⊙.