bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scaling up hepatitis C testing and linkage-to-care among people who use drugs: lessons learned from a pilot project implemented at a supervised consumption site
Authors: Hannigan Alannah , Krishnan Nandini , Singh Kirti , Bytelaar Shannon , Schmitz Deb , Bartlett Sofia , Hall David , Barrios Rolando , Montaner Julio S. G. , Harris Marianne , Hull Mark W. , Salters Kate A. 
Published: February 2025

Abstract

Background
Despite rolling out publicly-funded hepatitis C virus (HCV) treatment across the province of British Columbia (BC), Canada, 35% of people returning positive HCV RNA results in 2020 did not initiate treatment. The HCV epidemic in Canada continues to disproportionately impact people who use drugs and yet, this population has the lowest proportional uptake of HCV treatment. Evidence suggests linkages to healthcare after diagnosis is one of the key factors that impacts uptake of HCV treatment among this priority population. The Hep C Connect pilot project was implemented to characterize HCV testing outcomes and linkage-to-care rates within a low-barrier supervised consumption site (SCS) in Vancouver, BC.

Methods
All clients (aged ≥ 19 years) attending the Hope to Health SCS in Vancouver, Canada were invited to participate in the pilot study between November 2021 and December 2022. Interviewer-led surveys were conducted and participants were offered same-day HCV point-of-care (POC) antibody (Ab) testing. Participants received a cash honorarium for sharing their time and experiences. Descriptive statistics are shared in order to describe the reach and impact of this pilot project.

Results
The study enrolled 186 participants including 123(66.1%) men and 59(31.7%) women, with a median age of 42 (Q1,Q3- 34,49). Forty-seven (25.3%) participants stated that they use an SCS regularly and 123(66.1%) stated that they get new rigs every day. Notably, 64(34.4%) participants reported not having a primary care provider yet more than three-quarters of the participants (144, 77.4%) reported having been ever tested for HCV. All 186 participants agreed to HCV POC Ab testing with 59.7% returning a positive HCV POC Ab result. Despite good HCV POC Ab uptake and high rates of HCV knowledge, 49(44.1%) of the HCV Ab positive participants chose not to engage in confirmatory ribonucleic acid (RNA) testing.

Conclusions
The Hep C Connect pilot explored the gaps evident in the HCV cascade-of-care as it pertains to people who use drugs. Findings suggest that, despite high levels of HCV knowledge, the employment of blood draw RNA testing deterred people from engaging in confirmatory testing. Improving the HCV cascade-of-care will require alternative strategies that are more acceptable to this population.
Population genetic analysis of the liver fluke Fasciola hepatica in German dairy cattle reveals high genetic diversity and associations with fluke size
Authors: Hecker Anna Sophie , Raulf Marie-Kristin , König Sven , May Katharina , Strube Christina 
Published: February 2025

Abstract

Background
The liver fluke Fasciola hepatica is one of the most important endoparasites in domestic ruminants worldwide and can cause considerable economic losses. This study presents the first population genetic analysis of F. hepatica in Germany and aims at providing new insights into genetic diversity and population structure.

Methods
A total of 774 liver flukes, collected from 60 cows of 17 herds and 13 cows of unknown herd origin, were subjected to comparative analysis of two mitochondrial genes (cox1 and nad1), one nuclear region (internal transcribed spacer (ITS)-1) and eight nuclear microsatellite markers. In addition, individual fluke measurements allowed comparison of morphometric differences between genotypes.

Results
The nuclear ITS-1 region showed minimal variability, with 772 of 774 flukes having identical sequences, while the mitochondrial sequences revealed a high genetic diversity, with 119 distinct haplotypes, a mean haplotype diversity (Hd) of 0.81 and a mean nucleotide diversity (π) of 0.0041. Mitochondrial phylogenetic analysis identified two clusters with no clear association with the host or farm of origin. In the microsatellite analysis, all eight loci were highly polymorphic, with a mean allele frequency of 19.0 and a mean genotype frequency of 73.5 per locus. A total of 500 unique multilocus genotypes (MLGs) were found across all fluke samples, indicating that 68.5% of all genotypes were unique. A mean expected heterozygosity of 0.71 suggested a high potential for adaptability and the number of migrants (Nm = 3.5) indicated high gene flow between farms. Population structure analysis based on microsatellite data revealed that flukes from two farms differed genetically from the others. Linear mixed model results revealed that fluke length differed significantly between the two mitochondrial clusters, although it should be noted that fluke age could not be considered in the analyses.

Conclusions

Fasciola hepatica in German dairy farms showed high genetic diversity and gene flow. The differences in population structure identified by mitochondrial sequences compared with microsatellite loci highlight the benefits of analysing genetic markers of different origins. This is the first study to correlate fluke morphometry measurements with genetic markers, indicating that the identified markers can influence fluke size.

Graphical Abstract
What can simulation educators learn from the reluctant participant? An exploration of the factors influencing engagement amongst adult learners participating in paediatric simulation training
Authors: Newhouse Laura , Polwart Ngaire 
Published: February 2025

Abstract

Background
Simulation educators are typically passionate advocates for simulation as a training modality; however, we frequently encounter participants who do not share our enthusiasm. The voice of the highly engaged participant is well publicised; however, the experience of those who do not readily engage in simulation has not been extensively studied and may offer valuable insights for educators. This qualitative study will explore factors which influence learner engagement in paediatric simulation training, informing the practice and approach of simulation educators to optimise learning experiences.

Methods
We conducted a reflexive thematic analysis of 12 semi-structured interviews with medical and nursing professionals from a large paediatric teaching hospital in New Zealand who self-identified as reluctant participants in simulation-based education. Interviews explored factors which have influenced their engagement in simulation-based education over the course of their careers.

Results
Three overarching themes were developed which describe the factors influencing adult-learner engagement in simulation-based education. The first, participant anxiety, explores the participants’ narratives related to anxiety before, during and even following simulation which can impact on their ability to engage in current and subsequent simulation-based education. The second, protective behaviours, relates to the defensive mechanisms employed by participants in response to vulnerability experienced during simulation activities. The third theme, perception of the facilitator, examines the impact of simulation facilitator characteristics and behaviours on learner engagement.

Conclusions
These narratives highlighted that regular simulation activities with transparent learning objectives in which facilitators demonstrate vulnerability and adopt a co-learner attitude act to reduce participant anxiety. Emergent defensive behaviours, particularly “group shielding”, interfere with collective learner engagement and should be both recognised and addressed by facilitators. Finally, there are potential discrepancies in the perceptions of facilitators and learners regarding what constitutes psychologically safe education environments. A collaborative and iterative approach to simulation-based education design may act to improve psychological safety for reluctant participants.
Meat quality, safety, dietetics, environmental impact, and alternatives now and ten years ago: a critical review and perspective
Authors: Oleinikova Yelena , Maksimovich Sviatoslav , Khadzhibayeva Irina , Khamedova Elana , Zhaksylyk Aizada , Alybayeva Aigul 
Published: February 2025

Abstract
Meat consumption is growing steadily. As with any research, meat investigation requires an overall view of the study field to identify current directions and reveal prospective trends. The number of publications on meat research is growing steadily and reaching several thousand publications per year. This creates difficulties in covering all available information in the field and forces researchers to increasingly limit themselves to narrow issues in their direction. We analysed the main trends in meat research published recently and ten years ago. We identified areas of research in the field of meat based on abstracts of articles with the word “meat” in the title published in the Web of Science database in the time intervals 2000–2003, 2010–2013 and 2020–2023. We also mapped terms from articles directly related to meat using VOSviewer and the OpenAlex application programming interface. Among the selected dominant directions of the Web of Science, research areas were systematised based on abstracts of articles and reviews: 1182 publications in 2013 and 2610 publications in 2023. Such an increase in the number of publications indicates a sharp rise in interest in the topic and the existence of questions that need to be resolved. Therefore, an overview of the main directions in meat research in 2013 and 2023 was presented. Research areas with a declining share of articles and actively developing directions were identified, and unresolved pressing questions and trends were presented. The revealed changes demonstrate a shift from microbiology and technology of obtaining meat and meat products towards research methods development, problems of nutrition, and global warming. In conclusion, the prospects for research in these areas have been considered. The need to regulate the negative effects of meat production and consumption justifies the rationality of interdisciplinary approaches integrating environmental, health, and ethical perspectives. The most promising areas for further research are rationale and developing strategies to reduce meat consumption.

Graphical Abstract
A Case of an Anterior Lingual Mandibular Bone Depression in a Child
Authors: Meriç Ezgi 
Published: February 2025

This report presents imaging findings of a rare case of anterior lingual mandibular bone depression in a child. These defects are typically localized at the lingual cortical area of the lower jaw and have been diagnosed casually during routine radiographic examination. We presented very different information about the prognosis and formation hypotheses of the lesion observed in a child than has been presented so far. The purpose of this report is also to introduce a new case of an anterior lingual mandibular bone defect and to focus on clinical features, alternative diagnostic imaging sources differential diagnoses and review the current literature. CPD/Clinical Relevance: An anterior lingual mandibular bone depression mimicking a Stafne bone defect is described.
Conversations that Count
Authors: Binnie Rebecca SL , Sinclair Serena 
Published: February 2025

Good communication between dentist and patient is essential. The ability to communicate with patients about sensitive topics can also improve patient outcomes and help facilitate positive behaviour change. This article reviews ways in which sensitive topics, including oral health, smoking, alcohol use, recreational drug use and diet, can be approached by dental professionals. Dental professionals are well placed to give comprehensive advice concerning oral health. Other topics can be approached using brief interventions that can be carried out within the limited time available to dental practitioners. Brief intervention is an approach to assess and increase patients' motivation or readiness to change unhealthy behaviours. Self-help materials that patients can be given and signposted to are also highlighted. CPD/Clinical Relevance: Structured approaches are available to assist dental clinicians to have conversations with patients around sensitive topics.
The orthodontic–paediatric interface. Part 2
Authors: Donnell Christopher C , Patel Trishna A , Kirby Jennifer E , Frawley Tom 
Published: February 2025

Dental decisions made during childhood and adolescence can have long-term implications. The orthodontic–paediatric interface ensures that children are assessed and managed by the right people, in the right place, at the right time. This two-part series offers general dental practitioners (GDPs) and specialists an update on common joint orthodontic–paediatric problems in the mixed dentition alongside practical considerations to resolve them. The second article focuses on: interceptive orthodontics, crossbites, unerupted central incisors, ectopic and impacted canines, and enamel and dentine disorders. CPD/Clinical Relevance: This series will enable GDPs to recognize and manage common problems in primary care.
Tendência dos indicadores epidemiológicos e operacionais da hanseníase em menores de 15 anos na região Nordeste do Brasil, 2013 - 2022
Authors: De Carvalho Souza Ana Paula , Dias de Araújo Olivia , Medeiros Mascarenhas Márcio Dênis , Pacheco Rodrigues Malvina Thais , Ximenes Andrade Jesusmar , Ferraz do Nascimento Fernando 
Published: February 2025

Objetivo: Analisar a tendência dos indicadores epidemiológicos e operacionais da hanseníase na região Nordeste do Brasil, no período de 2013 a 2022. Método: Estudo de séries temporais. Indicadores operacionais e de morbidade da hanseníase foram calculados a partir de dados do Sistema de Informação de Agravos de Notificação. Utilizou-se regressão de Prais-Winsten. Resultados: As taxas de detecção de hanseníase em menores de 15 anos (VPA= -11,3; IC95% -15,8; -6,5) e proporção de cura (VPA= -5,0; IC95% -9,7; -0,0) apresentaram tendência decrescente. Proporção de grau 2 de incapacidade física (GIF2) (VPA= 6,8 IC95% -0,3; 14,5) e de contatos examinados (VPA= -0,1; IC95% -2,3; 2,2) mostraram tendência estacionária. Conclusão: Apesar da tendência de diminuição de casos na população menor de 15 anos, há a necessidade de atenção ao parâmetro de endemicidade, que demonstra dificuldades no rastreio da cadeia epidemiológica da transmissão, origens de transmissão persistentes e retardo no diagnóstico e tratamento da doença. A permanência de casos com GIF2, revela a necessidade de aumentar o rastreio de contatos e o tratamento visando alcançar a cura.
Disclosure and control of fraud in financial statements in the context of business management on the example of the polish economy
Authors: Rak Yevhen 
Published: February 2025

All business entities that conduct economic activities in the capital market are in contact with the revenues and costs that these activities gen-erate. This has to do with the business operations performed. This is a sphere that cannot be ignored in the preparation of financial state-ments, the “reading” of the report or the audit conducted by the auditor in the context of business management. It is also an area particularly vulnerable to the risk of manipulation. These manipulations are related to the tweaking or smoothing of the financial result. Accordingly, the auditor is tasked with examining income and expenses, assessing their accuracy and reasonableness, verifying the correctness of presenta-tion and, on the basis of source documents and tests performed supported by working papers, issuing the final product of the audit - which is an opinion with a report - based on professional skepticism and judgment. These factors are necessary to assess the risks associated with the audit of the various elements affecting the financial result, as well as to be cautious about the data presented. This article aims to conduct a fraud analysis and show the essence and role of the auditor in the audit of the financial statements, as well as how to deal with the auditor when material irregularities are detected.
Regional Development of Maritime Tourism and Accessibility Gap of North Buton, South East Sulawesi, Indonesia
Authors: Isfa Sastrawati Ihsan , V. Patandianan Marly , V. Natalia Venny , Pati Sakka 
Published: February 2025

Indonesiaâ€™s decentralised authority policy inspire the application of local economic development approach in many region which drive the economic growth base on their natural resources. As a maritime region, North Buton has a potential coastal area that can be explored as a tourism industry. This sector is one of the economic catalysts that succeed in many regions and countries in the world. North Buton has many potential in maritime tourism resources but many of them remain concealed or undeveloped due to the lack of transport services. Accessibility is the main feature in tourism industry, this reason drive the purposes of this research, that is, identify the maritime tourism destinations and the accessibility services and development in the North Buton Region. The research used spatial analysis by using Geographical Information Systems (GIS) and photo mapping. The tourism destinations were identified by considering the availability of attractions, amenities, and access. Then, accessibility was identified by measuring the distances, time and routes of transportation to reach the tourism destinations.Â The results of the analysis showed that there are 28 kind of maritime tourism objects which lay along the North Buton urbanized coastal area. Most ofÂ the objects can be achievedÂ with longer land trip round the region. The shorter route uses sea transport is high potential but not available yet.Â Â
Classroom interaction patterns of high and low achievers at an undergraduate private university in Dubai
Authors: Salameh Walid , A. Sathakathulla A. 
Published: February 2025

This research emphasizes a study which was conducted to observe the patterns of classroom interactions of both high and low achieving students at a private university in Dubai. The main aspects of the research were: (1) Frequency of interactions; (2) Nature of interactions; and (3) Reasons for avoided interactions initiation. It was determined that more interactions were initiated by high achieving students than by low achieving students, although low achieving students attained a similar level of interaction as high achievers when discussion was initiated by the teacher. It was also observed that low achieving students prefer privacy when asking a question or checking for correctness of answers, whereas high achievers exhibited more confidence towards asking questions and providing comments on discussion. Surveying students regarding the reasons they avoid initiating interactions revealed that high achieving students lack motivation as they are probably under-challenged, while low achieving students lack confidence as well as motivation.Â Â Â
The New Shape of Global Higher Education in COVID-19 Era
Authors: Khalil M. , Afifi M. 
Published: February 2025

The effect of COVID-19 in the world made us face unprecedented challenges. It reflects a model of the Butterfly effect. The butterfly effect is the sensitive dependence on initial conditions in which a small change in one state of a deterministic nonlinear system can result in large differences in a later state. Governments have introduced emergency measures to save lives, Working from home has gone from perk to necessity, Lockdowns and closed borders have become part of 2020. As global citizens, it is crucial that we develop social responsibility towards each other to safeguard the entire humanity. At this stage, itâ€™s still impossible to say which phase of the pandemic we find ourselves in. Are we at the beginning of the end, or at the end of the beginning? Will we see a second wave of infections? When will a vaccine be ready? We are going through challenging times and the world around us is changing fast. We may not have all the answers to these ques-tions, but we do know that the world will witness lasting changes due to COVID-19 pandemic. COVID-19 as an international pandemic, has shed its profound impact on all daily aspects of life in the entire world; political, economic, social and apparently the education sector has not been immune.Â Â
Trends of eutrofication and effects of measures in Feitsui reservoir during 1987 â€“ 2018
Authors: Liao Yen-Hsiung 
Published: February 2025

Purpose: Reservoir watershed is one of the most important sources of domestic water of people. The quality of water is crtical for the users.Approach: Using trends of environmental water quality information during 1987 â€“ 2018. We approached the Carlson trophic state index (CTSI) and evaluated the effects of measures on water quality of Feitsui reservoir compared to the controlled Shihmen reservoir.Results: The CTSI (46.4) was peak in 2001 and decreased to 36.8 in 2018. Water quality was improved after the establish of Best Management Practices (BMPs) after 2003. The CTSIs in Feitsui reservoir were lower than that in Shihmen reservoir generally.Conclusions: Non-point source pollution could cause a higher CTSI. The eutrofication shold be prevented by use of total phosphorus.Â Â
Investigation of the Quality of Shapura Lake Water, Bhopal, Madhya Pradesh, India
Authors: . Salahuddin 
Published: February 2025

The present study is based on Physico-Chemical Parameter of Shahpura Lake of Bhopal, Madhya Pradesh. The water of Shahpura Lake is polluted due to substantial release of contaminated materials without acceptable treatment to expunge pernicious compounds. The Physico-Chemical parameters such as Chloride(Cl), Total Hardness(TH), Alkalinity(A), pH(pH), Electric Conductivity(EC), Total Dissolved Solids (TDS), Fluoride(F), Iron(Fe), Turbidity(Td), Dissolved Oxygen (DO), Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand(COD) and Sulphate (S)Â were examined to know the present status of the Lake water quality. Statistical analysis like Pearson Correlation matrix and Factor loadings were implemented to the data set to know the relationship among the studied parameters.Â Â Â
Geoelectric / hydrogeologic characteristics and aquifer types of ground water in the basement rocks of the area south of Zakum bello. Nasarawa state. north-central Nigeria
Authors: O. Oluyede Kehinde 
Published: February 2025

Interpretation of vertical electrical soundings (VES) and study of lithologic logs were carried out to identify the geoelectric/hydrogeologic characteristics of the Basement Complex rocks in the area south of Zakum Bello. Geoelectric sections drawn from the interpretation results (layer resistivities and thicknesses) reveal mainly four to five layers with the first four layers constituting the weathered basement. Two aquifer types were identified. These are fractured (confined) and weathered (unconfined) aquifer. Ground water yield varies from 0.63 L/S (for the weathered layer aquifer) to 0.28 L/S (for the fractured aquifer) making the weathered basement more prolific. The fracture occurred mainly in the gneiss and thickness ranges from 5 to 10m mainly within the depth of 15 to 40m. Chemical analysis of borehole, well and stream waters which include titrimetric method for chloride and bicarbonate, UV method for nitrate and calorimetric method for sulphate shows the water to be slightly acidic and indicate good water quality throughout the area despite the variation in lithologic units. Prospective borehole sites were recommended for villages or communities without borehole.Â Â