bluuebunny/crossref_metadata_2025_split huggingface dataset:
The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review
Authors: Murray Siobhan C. , McNamara Claire , Chatzi Anna V. 
Published: May 2024

AbstractImplantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of relevant discussions among professionals and patients. Available literature was reviewed using four electronic databases to identify issues that may deter healthcare professionals from having important deactivation discussions and to address considerations for ICD management prior to the EOL. The search resulted in the retainment of 12 studies. Three themes emerged from the data: barriers and facilitators, ethical considerations in clinical practice, and nurse's role. Lack of knowledge, which has been associated with cultural differences, has been found among the barriers, and interdisciplinary education and open communication appeared as facilitators. As clinicians' ethical considerations and fears emerged from the literature, nurses' special role has not been sufficiently supported. Complex care requires facilitation by multidisciplinary teams and education around the device's function regarding EOL issues. Establishing expert consensus statements on advance care planning might help define the distinct roles of each healthcare practitioner involved. Further research is needed in addressing the identified gaps.
Finerenone in patients with heart failure with mildly reduced or preserved ejection fraction: Rationale and design of the FINEARTS‐HF trial
Authors: Vaduganathan Muthiah , Claggett Brian L. , Lam Carolyn S.P. , Pitt Bertram , Senni Michele , Shah Sanjiv J. , Voors Adriaan A. , Zannad Faiez , Desai Akshay S. , Jhund Pardeep S. , Viswanathan Prabhakar , Bomfim Wirtz Antonieta , Schloemer Patrick , Lay‐Flurrie James , McMurray John J.V. , Solomon Scott D. 
Published: May 2024

ABSTRACTAimSteroidal mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, are strongly recommended in the treatment of patients with chronic heart failure (HF) with reduced left ventricular ejection fraction (LVEF), but the balance of efficacy and safety in those with higher LVEF has not been well established. Broad use of steroidal MRAs has further been limited in part due to safety concerns around risks of hyperkalaemia, gynecomastia, and kidney dysfunction. These risks may be mitigated by the unique pharmacological properties of the non‐steroidal MRA finerenone. The FINEARTS‐HF trial is designed to evaluate the long‐term efficacy and safety of the selective non‐steroidal MRA finerenone among patients with HF with mildly reduced or preserved ejection fraction.MethodsFINEARTS‐HF is a global, multicentre, event‐driven randomized trial evaluating oral finerenone versus matching placebo in symptomatic patients with HF with LVEF ≥40%. Adults (≥40 years) with HF with New York Heart Association class II–IV symptoms, LVEF ≥40%, evidence of structural heart disease, and diuretic use for at least the previous 30 days were eligible. All patients required elevated natriuretic peptide levels: for patients in sinus rhythm, N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) ≥300 pg/ml (or B‐type natriuretic peptide [BNP] ≥100 pg/ml) were required, measured within 30 days (in those without a recent worsening HF event) or within 90 days (in those with a recent worsening HF event). Qualifying levels of NT‐proBNP or BNP were tripled if a patient was in atrial fibrillation at screening. Estimated glomerular filtration rate <25 ml/min/1.73 m2 or serum potassium >5.0 mmol/L were key exclusion criteria. Patients were enrolled irrespective of clinical care setting (whether hospitalized, recently hospitalized, or ambulatory). The primary endpoint is the composite of cardiovascular death and total (first and recurrent) HF events. The trial started on 14 September 2020 and has validly randomized 6001 participants across 37 countries. Approximately 2375 total primary composite events are targeted.ConclusionsThe FINEARTS‐HF trial will determine the efficacy and safety of the non‐steroidal MRA finerenone in a broad population of hospitalized and ambulatory patients with HF with mildly reduced or preserved ejection fraction.Clinical Trial Registration: ClinicalTrials.gov NCT04435626 and EudraCT 2020‐000306‐29.
Visible‐Light‐Induced Oxidation of Silanes with SF6 for Efficient Synthesis of Siloxanes
Authors: Bi Yu‐Xiang , Zhao Yue , Zhang Qing‐Qing , Guo Xiao‐Yu , Dai Jing‐Cheng , Jin Ruo‐Xing , Wang Xi‐Sheng 
Published: May 2024

AbstractA visible‐light‐induced strategy utilizing sulfur hexafluoride (SF6) as distinctive oxidant and water as the oxygen source to transform silanes into siloxanes has been developed under mild conditions, realizing the efficient utilization and degradation of the strong greenhouse gas, sulfur hexafluoride, simultaneously. Mechanistic experiments demonstrate that the reaction proceeds through a radical pathway, and it has been confirmed that the oxygen atoms in the resulting siloxanes indeed originate from water by isotopic labeling experiments with 18O.
Synthesis of diesel‐like fuels using waste cooking oil and waste polyethylene via Co‐pyrolysis process
Authors: Singh Divyansh , Paul Abhishek 
Published: May 2024

AbstractThis study investigated the effects of different proportions of waste polyethylene (WP) and waste cooking oil (WCO) on the chemical and physical properties of the resulting co‐pyrolysis oil produced in an indigenously developed laboratory‐scale fixed bed batch‐type reactor. The proportion of WCO was altered in increments of 10% from 10% to 90%, and correspondingly, the proportion of WP was adjusted from 90% to 10% (by weight). The highest liquid fuel yield, reaching 70.9% by weight, was achieved using a 40:60 ratio of WCO to WP (W40P60) at a constant heating rate of 12°C and a temperature of 500°C. The obtained fuel exhibits promising properties, including a high calorific value (max HHV around 45.63 MJ/kg) and other advantageous properties such as low viscosity, low oxygen and nitrogen content, and absence of sulfur. Fourier‐transform infrared spectroscopy (FTIR) and gas chromatography–mass spectroscopy (GCMS) were examined on the resulting liquid fuel. The GC–MS spectra predominantly display alkanes, constituting approximately 41% by weight, and alkenes, making up roughly 20% by weight. These analyses revealed properties akin to commercial diesel, emphasizing the potential of waste cooking oil and waste polyethylene proportions in liquid diesel like fuel production.
Taxonomy and ecology of Elaeocarpus venustus Bedd. (Elaeocarpaceae): An endemic and Critically Endangered tree species of the Western Ghats, India
Authors: Ramasubbu Raju , Venkatesh Palanivel , Anjana Surendran , Priya Prasannan 
Published: May 2024

AbstractElaeocarpus venustus is a steno‐endemic and Critically Endangered tree species of the Agasthyamalai Biosphere Reserve, southern Western Ghats, India. Due to its restricted distribution and specific habitat, a detailed field survey of existing populations was carried out. In order to clarify the taxonomic circumscription of this species in view of earlier literature, a revised taxonomic description is presented—together with details of the populations and ecology of this little‐known species and photographic documentation.
On the convergence of the Rhie–Chow stabilized Box method for the Stokes problem
Authors: Negrini G. , Parolini N. , Verani M. 
Published: May 2024

AbstractThe finite volume method (FVM) is widely adopted in many different applications because of its built‐in conservation properties, its ability to deal with arbitrary mesh and its computational efficiency. In this work, we consider the Rhie–Chow stabilized Box method (RCBM) for the approximation of the Stokes problem. The Box method (BM) is a piecewise linear Petrov–Galerkin formulation on the Voronoi dual mesh of a Delaunay triangulation, whereas the Rhie–Chow (RC) stabilization is a well known stabilization technique for FVM. The first part of the article provides a variational formulation of the RC stabilization and discusses the validity of crucial properties relevant for the well‐posedness and convergence of RCBM. Moreover, a numerical exploration of the convergence properties of the method on 2D and 3D test cases is presented. The last part of the article considers the theoretically justification of the well‐posedness of RCBM and the experimentally observed convergence rates. This latter justification hinges upon suitable assumptions, whose validity is numerically explored.
Effect of tragacanth gum–chitin nanofiber film containing free or nano‐encapsulated cumin essential oil on the quality of chilled turkey burgers packed with oxygen absorber
Authors: Shahabi Nasim , Fallah Aziz A. , Sami Masoud , Habibian Dehkordi Saeid 
Published: May 2024

AbstractThis research was undertaken to assess the effect of tragacanth gum–chitin nanofiber (TG–CNF) film containing free (CEO) or encapsulated cumin essential oil (CNE) combined with oxygen absorber (OA) packaging on the shelf‐life of ready‐to‐cook (RTC) turkey breast burgers during chilled storage. The experimental groups were OA and TG–CNF as single treatments, TG–CNF + CEO, TG–CNF + CNE, and TG–CNF + OA as binary treatments, TG–CNF + CEO + OA and TG–CNF + CNE + OA as ternary treatments, and control. The samples were stored at 3°C for 20 days and analyzed for microbial, physicochemical, and sensory attributes. Binary treatments, when compared to single treatments, and ternary treatments, when compared to binary treatments, exhibited enhanced effectiveness in managing microbial growth, hindering physicochemical alterations, and decelerating sensory alterations. At day 20, TG–CNF + CNE + OA group was identified as the most effective group in inhibiting the growth of total mesophilic bacteria (TMB), total psychrophilic bacteria (TSB), and coliforms (final counts were 4.8, 4.16, and ≤1 log CFU/g, respectively), and TG–CNF + CNE + OA and TG–CNF + CEO + OA groups were known as the most effective groups in inhibiting lactic acid bacteria (LAB) (final counts were 4.71 and 5.15 log CFU/g, respectively). Furthermore, the TG–CNF + CNE + OA treatment proved to be the most effective group in reducing the total volatile nitrogen (TVN) (final level was 19.2 mg N/100 g) and thiobarbituric acid reactive substances (TBARS) (final level was 0.119 mg malondialdehyde (MDA)/kg). TG–CNF + CNE + OA and TG–CNF + CEO + OA were the most efficient groups to delay the increasing rate of cooking loss (final values were 23.3% and 24.6%) and pH (final values were 7.01 and 6.99). The sample's shelf‐life was 4 days in control and TG–CNF, 8 days in OA and TG–CNF + OA, 12 days in TG–CNF + CEO, 16 days in TG‐CNF + CNE and TG–CNF + CEO + OA, and at least 20 days in TG–CNF + CNE + OA. As a result, the incorporation of TG–CNF + CNE alongside OA packaging emerges as a highly effective active packaging method for preserving RTC turkey breast burgers during chilled storage.
Motivating learning goal orientation and job performance: Leadership training and development
Authors: Lin Chieh‐Peng , Li Yan‐Lin 
Published: May 2024

AbstractDrawing upon role identity theory and human capital theory, this study explored the role of paternalistic leadership in terms of job performance. Empirical analyses were performed based on a field investigation involving agents from three large insurance companies in Taiwan. The analyses first showed that benevolent leadership indirectly influenced job performance only through strategy role commitment, while authoritarian, benevolent, and moral leadership indirectly influenced job performance through affective dependence. Second, strategy role commitment influenced job performance directly and indirectly through learning goal orientation, whereas affective dependence influenced job performance indirectly only through learning goal orientation. Third, management position positively moderated the positive effects of strategy role commitment on both learning goal orientation and job performance. Last, theoretical and practical implications were discussed based on the results.
Tape‐casting electrode architecture permits low‐temperature manufacturing of all‐solid‐state thin‐film microbatteries
Authors: Ke Bingyuan , Zhang Congcong , Cheng Shoulin , Li Wangyang , Deng Renming , Zhang Hong , Lin Jie , Xie Qingshui , Qu Baihua , Peng Dong‐Liang , Wang Xinghui 
Published: May 2024

AbstractAlong with the constantly evolving functional microsystems toward more diversification, the more rigorous design deliberation of pursuing higher mass‐loading of electrode materials and low‐temperature fabrication compatibility have imposed unprecedented demand on integrable all‐solid‐state thin‐film microbatteries. While the classic thin‐film intercalation cathode prepared by vacuum‐based techniques inevitably encountered a post‐annealing process, tape‐casting technologies hold great merits both in terms of high‐mass loading and low‐temperature processing. In this work, a novel microbattery configuration is developed by the combination of traditional tape‐casting thick electrodes and sputtered inorganic thin‐film solid electrolytes (~3 μm lithium phosphorus oxynitride). Enabled by physically pressed or vapor‐deposited Li as an anode, solid‐state batteries with tape‐casted LiFePO4 electrodes exhibit outstanding cyclability and stability. To meet integration requirements, LiFePO4/LiPON/Si microbatteries were successfully fabricated at low temperatures and found to achieve a wide operating temperature range. This novel configuration has good prospects in promoting the thin‐film microbattery enabling a paradigm shift and satisfying diversified requirements.
Twenty‐eight days of repeated dose sub‐acute toxicological evaluation of polyherbal Ayurvedic medicine BPGrit in Sprague–Dawley rats
Authors: Balkrishna Acharya , Sinha Sandeep , Bhattacharya Kunal , Varshney Anurag 
Published: May 2024

AbstractA pre‐clinical toxicological evaluation of herbal medicines is necessary to identify any underlying health‐associated side effects, if any. BPGrit is an Ayurveda‐based medicine prescribed for treating hypertensive conditions. High‐performance liquid chromatography‐based analysis revealed the presence of gallic acid, ellagic acid, coumarin, cinnamic acid, guggulsterone E, and guggulsterone Z in BPGrit. For sub‐acute toxicity analysis of BPGrit, male and female Sprague–Dawley rats were given repeated oral gavage at 100, 300, and 1000 mg/kg body weight/day dosages for 28 days, followed by a 14‐day recovery phase. No incidences of mortality, morbidity, or abnormal clinical signs were observed in BPGrit‐treated rats throughout the study period. Also, the body weight and food consumption habits of the experimental animals did not change during the study duration. Hematological, biochemical, and histopathological analysis did not indicate any abnormal changes occurring in the BPGrit‐treated rats up to the highest tested dose of 1000 mg/kg body weight/day. Finally, the study established the “no‐observed‐adverse‐effect level” for BPGrit at >1000 mg/kg body weight/day in Sprague–Dawley rats.
Survey of screw‐retained versus cement‐retained implant restorations used in both education and private dental practices
Authors: Found Anelyse Arata , Shah Shivani , Fouda Mohamed A. , Santos Maria Jacinta M. C. , Butler Sheila 
Published: May 2024

AbstractAimsIn the literature, it is still unclear if the decisions for selecting the type of implant crown‐retaining system are based on scientific‐based research or if the Universities’ choices, Implant marketing trends, or finances could have a major influence on the private dentists’ decisions.ObjectivesTherefore, this study aimed to evaluate the crown‐retaining system (cement‐ or screw‐retained) used in dental schools and private dental practices.MethodsA 13‐item questionnaire was sent to Canadian dental schools (n = 10) and dental offices in London (n = 298), Canada. The questionnaire included demographic questions and questions to reveal the dentists’ perspectives on prosthetic implant treatment between the two‐retaining systems. Results were analyzed using descriptive statistics and multinomial logistic regression (p = 0.05).ResultsTwenty‐four private dentists and five dental schools responded to the survey – 62.5% of private practitioners and 60% of universities reported using both systems. A trend was observed in using screw‐retained systems by dentists who graduated 5–10 years ago. Straumann, Astra, and Nobel Biocare were the private practices and dental schools’ preferred implant systems. The use of platform switching for all cases was selected by 54.2% of the private practitioners and 40% of the dental schools. Resin cement was the private practice's preferred cementation method; the dental schools used glass ionomer and zinc phosphate cement. The multinomial logistic regressions showed no statistical difference between the crown‐retaining system chosen and the decision factors. The laboratory technician's recommendations and cost influenced the decision‐making process for private dentists. For the universities, perio‐restorative outcome, implant position, survival rates, institute preferences, and evidence‐based research influenced the crown‐retaining system's decision‐making process. ConclusionThe Canadian dental schools and private practice reported using both screw‐ and cement‐retaining systems. However, there was a difference in the selection criteria as the universities showed a tendency towards a more research‐based approach in their decision, while for the private practices, the technicians’ recommendations and cost played a major role in the decision process. It was noted that the implant systems preconized by the Universities were observed to be used in private practices.
World Health Organization (WHO) guideline on the complementary feeding of infants and young children aged 6−23 months 2023: A multisociety response
Authors:   European Society for Paediatric Gastroenterology, Hepatology & Nutrition (ESPGHAN),   European Academy of Paediatrics (EAP),   European Society for Paediatric Research (ESPR),   European Academy for Allergy and Clinical Immunology (EAACI),   Federation of International Societies for Paediatric Gastroenterology, Hepatology & Nutrition (FISPGHAN),   Latin American Society for Pediatric Gastroenterology, Hepatology & Nutrition (LASPGHAN),   Pan Arab Society for Pediatric Gastroenterology and Nutrition (PASPGHAN),   Asian Pan‐Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition (AAPSGHAN),   North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN),   World Allergy Organization (WAO),   Asia Pacific Academy of Pediatric Allergy, Respirology & Immunology (APAPARI)
Published: May 2024

AbstractThe recent World Health Organization (WHO) guideline aims to provide evidence‐based recommendations on complementary feeding (CF) of healthy term infants and young children 6−23 months living in low‐, middle‐, and high‐income countries, including both breastfed and non‐breastfed children. Like WHO, our organizations aim to promote optimal infant and young child nutrition and health, with a focus on promoting breastfeeding as well as appropriate and timely CF. In this paper, we share our concerns about aspects of the guideline, some of which may have the potential to cause unintended harm in infants and young children and suggest alternative or modified proposals.
The influence of pretreatment respiratory sinus arrhythmia dimensions on trauma‐focused cognitive behavioral therapy outcomes: Findings from a randomized controlled feasibility trial
Authors: Brown Michelle P. , Shenk Chad E. , Allen Brian , Dunning Emily D. , Lombera Metzli A. , Bucher Ashley M. , Dreschel Nancy A. 
Published: May 2024

AbstractChild maltreatment is associated with respiratory sinus arrhythmia (RSA) dysregulation, a physiological indicator of emotion regulation that predicts elevated posttraumatic stress disorder (PTSD) symptoms and may be a mechanism of action for exposure‐based therapies, such as trauma‐focused cognitive behavioral therapy (TF‐CBT). Animal‐assisted therapy (AAT) has been proposed as an adjunct to TF‐CBT for improving emotion regulation following maltreatment. The current study reports findings from a randomized controlled feasibility trial (N = 33; Mage = 11.79 years, SD = 3.08; 63.6% White; 66.7% female) that measured youths’ resting RSA, RSA reactivity, and RSA recovery in response to a pretreatment laboratory challenge. We tested whether (a) lower pretreatment resting RSA was associated with blunted RSA during the challenge; (b) either of the pretreatment RSA dimensions predicted more severe pretreatment PTSD symptoms; and (c) either of the pretreatment RSA dimensions predicted less severe posttreatment PTSD symptoms and, as an exploratory aim, whether this was moderated by treatment group (i.e., TF‐CBT vs. TF‐CBT + AAT). Results from multiple linear regression indicated that, after controlling for pretreatment symptom severity, there was a large effect size for higher resting RSA predicting less severe caregiver‐reported posttreatment PTSD symptoms, β = −.52, p = .058, and higher RSA during recovery predicting less severe child‐reported posttreatment PTSD symptoms, β = −.70, p = .056, although these findings were not significant. These preliminary results offer important insights for future studies to investigate how the ability to regulate RSA informs which children need additional support to benefit from psychotherapeutic treatment.
Ocular rosacea: The often‐overlooked component of rosacea
Authors: Geng Ryan S. Q. , Slomovic Jacqueline , Bourkas Adrienn N. , Slomovic Allan , Sibbald Ronald G. 
Published: May 2024

AbstractOcular rosacea is a chronic inflammatory condition that affects the eyes and periocular skin as part of the broader cutaneous rosacea skin disease. Cutaneous rosacea is common, affecting approximately 5.5% of the global population, where up to 72% of patients will develop ocular involvement either before or after the cutaneous disease. Clinical features of ocular rosacea include Meibomian gland disease, blepharitis and conjunctivitis. Ocular rosacea reduces quality of life through various potential mechanisms including anxiety, social withdrawal and physical discomfort. If left untreated, ocular rosacea can reduce visual acuity and in severe cases, vision loss. Several topical and systemic treatment options are available, with efficacies based on their anti‐inflammatory properties. This review focuses on the clinical features of ocular rosacea, differential diagnoses and treatment options with the aim of aiding clinicians involved in the care of rosacea patients to better identify onset of the ocular manifestations of rosacea and prevent its severe complications.