bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oral pyogenic granuloma with calcification
Authors: Gautam Akancha Singh , Mandal Sneh , Divya V. C. 
Published: June 2024

Rationale:
Pyogenic granuloma (PG) is a commonly observed reactive soft-tissue lesion, often arising due to prolonged mild irritation or hormonal fluctuations in the oral cavity. Clinically, PG presents as a lesion with a smooth or lobulated appearance, which can be either sessile or pedunculated, and typically exhibits an hemorrhagic tendency. Very few cases of calcification in a PG have been reported in the past as these rarely exhibit ossification when viewed under a microscope.

Patient Concerns:
The following report is a case of a PG, that presented as a growth with occasional pain in the right upper back region of a 54 year old female. The patient reported no other concerns.

Diagnosis:
A provisional diagnosis of PG was given following thorough clinical and radiographic investigations. This was confirmed by a histopathological examination following an excisional biopsy.

Intervention:
The patient was treated with surgical excision as a part of the excisional biopsy of the lesion. Follow-up for the patient was done after 6 months, and there were no signs or indications of recurrence.

Outcomes:
The histopathological examination revealed regions of calcification, which are uncommon in PG, in addition to the characteristic hallmarks of proliferating endothelial cells, blood vessels, and inflammatory cells.
Comparative study of the efficacy of combined metformin–clomiphene citrate versus combined metformin–letrozole in induction of ovulation in overweight women with polycystic ovarian syndrome
Authors: Ghoneim Basma M , El-Gharib Mohamed N , El-Badry Amr MT , Abd El-Raoof Farahat Manal 
Published: June 2024

Background
Polycystic ovary syndrome (PCOS) is the common cause of infertility. Clomiphene citrate (CC) is the first-line treatment in ovulation induction. Metformin biguanide has been used in insulin resistance in PCOS women. Adding metformin to CC in the CC-resistant PCOS was highly effective in achieving ovulation in 68.6–77.7% of patients. Letrozole, aromatase inhibitor, its use in patients with CC-resistant PCOS achieved ovulation 54.6–84.4% of the time.

Aim
We aimed to compare the efficacy of combined metformin–CC to combined metformin–letrozole in ovulation induction in overweight infertile PCOS women.

Patients and methods
A prospective randomized study was conducted at Obstetrics & Gynecology Department in Tanta University Hospitals. In total, 40 infertile overweight cases with PCO were included. Cases were randomly allocated in two groups.

Results
The mean age was 26.40 ± 5.20 years for CC group and 26.50 ± 5.10 years for letrozole group. BMI was 27.50 ± 1.43 for CC group and 27.45 ± 1.36 for letrozole group. The duration of infertility was 2.90 ± 1.40 years for CC group and 2.88 ± 1.21 for letrozole group. There was insignificant difference in both groups as regards the follicles more than 18 mm and endometrial thickness. But, as regards progesterone level, there was a statistically significant increase in letrozole group than CC group (P<0.005). Concerning pregnancy rate, there was insignificant difference between two groups.

Conclusion
The present investigation demonstrated that both CC and letrozole are similarly viable in treatment of infertility in PCOS patients, when joined with metformin treatment.
Evaluation of the efficacy and outcome of endoscopic endonasal trans-sphenoidal surgery for treatment of pituitary apoplexy
Authors: Aly Hamad Omar M H , Ganna Ahmed A , Torky Samy M , El Gamal Ehab E 
Published: June 2024

BackgroundPituitary apoplexy (PA) is a very serious clinical syndrome with serious long-term effects. It can be managed either conservatively or surgically depending on the presentation and co-morbidities of each case.AimIs to evaluate the outcome of the endoscopic trans-sphenoidal approach in the treatment of patients with PA and to evaluate its safety and efficacy.Patients and methodsThis is a combined retrospective and prospective study on 14 patients with PA who underwent endoscopic endonasal trans-sphenoidal surgery. The analysis included demographics, risk factors, symptoms, neuro-endocrinal deficits, neuroimaging, complications, and outcomes.Results14 patients (mean age was 47.21) were included. Preoperative symptoms included headache (100%), ocular mobility (78.6%), and visual deficits (92.9%). Radiological findings showed that (21.4%) were necrotic only, while (78.6%) were both necrotic and hemorrhagic. 100% of patients had resolved headache. (23.1%), (61.5%), and (15.4%) of patients had recovered, partially improved, and no change in visual acuity respectively. (72.7%) had recovered extraocular palsies, (18.2%) were partially improved, and (9.1%) had no change in extraocular palsies. (23.1%), (46.2%), and (30.8%) had recovered, partially improved, and no change in hormonal functions, respectively. (76.9%) needed long-term replacement therapy. (7.1%) had partial tumor resection, (57.1%) had subtotal resection, (35.7%) had gross total resection, and (100%) had tumor regression and no recurrence.ConclusionEndoscopic endonasal trans-sphenoidal surgery is a safe and effective treatment for PA with excellent neurological outcome, good visual outcome, low rates of complications, and recurrence. However, it has Poor hormonal outcomes.
Histological study on the effect of açai berry extract in the treatment of fundic mucosal injury in adult male albino rat
Authors: Khallaf Yassmin AMH , Saeid Mona TSA , Laag Essam MI , Abouraia Azza AM 
Published: June 2024

Background
Gastric injury is a worldwide medical problem. It is caused by many factors. Açai berry is a fruit with many potential medical properties that gained much international interest.

Aim
To evaluate the possible role of açai berry extract in the treatment of fundic mucosal injury in adult male albino rats.

Materials and methods
This work was done on 40 adult male albino rats that were divided into; group I (control) (10 rats), group II (10 rats) which were given açai berry extract orally at a dose of 300 mg/kg once per day for 14 days, group III (10 rats) which were given a single dose of diclofenac orally at a dose of 100 mg/kg for induction of gastric injury, and group IV (10 rats) that were given single oral dose of diclofenac then received açai berry extract for 14 days. Specimens from the fundus were processed and stained by hematoxylin and eosin.

Results
Group III showed exfoliation of surface epithelial cells and gastric glands, infiltration of lamina propria with inflammatory cells, and congestion of the blood vessels. Cytoplasmic vacuolations were detected in different cells. Group IV revealed improved changes that were detected in group III.

Conclusion
Açai berry extract is effective in the treatment of gastric injury.
Assessment of left ventricular function in asthmatic children using speckle tracking and tissue doppler echocardiography
Authors: Ali Somia , Badreldeen Al Shimaa , Razik Ahmed Abdel , El Razaky Osama , Elmeazawy Rehab 
Published: June 2024

Background
Acute bronchial asthma affects many organs including the cardiovascular system. Recurrent hypoxia and the production of inflammatory mediators lead to chronic inflammation, pulmonary vasoconstriction, and pulmonary hypertension, which can affect cardiac function.

Aim
This study aimed to assess left ventricular function in children with acute bronchial asthma using two-dimensional (2D), three-dimensional (3D) speckle tracking echocardiography (STE), and tissue doppler imaging (TDI).

Patients and methods
Fourty-five children with moderate persistent asthma aged 5–16 years and 15 matched controls were enrolled in this study. In addition to pulmonary function testing with spirometry, all participants underwent cardiac evaluation using conventional echocardiography, TDI, and 2D and 3D STE.

Results
The asthmatic children had significantly lower left ventricular systolic and diastolic functions (P = 0.017, P < 0.001, respectively) but significantly higher myocardial performance index (MPI) (P < 0.001) than that of the control group by TDI. By using 3D STE, 3D longitudinal strain, 3D circumferential strain, 3D area strain, and 3D radial strain were significantly lower in asthmatic children than the healthy control.

Conclusion
Children with asthma are more likely to have left ventricular dysfunction of different severities, which can be identified early using TDI and 3D STE.
Multidetector computed tomography in detection of pulmonary complications in patients with hematological neoplastic disorders
Authors: Ghoneem Mayada AA , Youssef Mohammed A , Badawy Manal E , Elbedewy Tamer A 
Published: June 2024

Background
Hematologic malignancy patients are liable to have pulmonary complications along the course of the disease due to the disease itself or its treatment.

Aim
Our study aimed to evaluate the role of multidetector computed tomography in detecting pulmonary complications in hematologic neoplasm patients.

Patients and methods
In all, 30 patients with hematological neoplastic disorders in this prospective study underwent radiological imaging for assessment of pulmonary complications at the Department of Radiodiagnosis and Medical Imaging, at Tanta University Hospitals and Tanta Cancer Center from 2019 to 2022. In all, 16 patients were males and 14 were females. Their age range was from 17 to 70 years with a mean age of 46.57 ± 13.56 years.

Results
Computed tomography showed an overall diagnostic accuracy of 100% in the diagnosis of amalgamated lymph nodes, pulmonary edema, and coronavirus disease 2019 pneumonia; otherwise, the least diagnostic accuracy was in the diagnosis of inflammatory conditions which was 90%. Thus, computed tomography showed very good results in almost all pulmonary complications except for inflammatory conditions.

Conclusion
Multidetector computed tomography is a very good modality in the early diagnosis of pulmonary complications in hematologic neoplasm patients.
Assessment of Acute Oak Decline in Latvia
Authors: Celma Laura , Zaļkalns Oskars , Šmits Agnis , Legzdiņa Līva , Silbauma Lauma , Ozols Jānis , Kļaviņa Dārta , Bokuma Gunita , Ruņģis Dainis 
Published: June 2024

Acute Oak Decline (AOD) is a complex disease affecting oaks (Quercus spp.). Typical symptoms include a dark, sticky exudate from bark cracks. Larval galleries of the beetle Agrilus biguttatus under the bark of affected trees are often reported. AOD is characterized by oak decline, after which a large proportion of the oaks die, but some survive. In Latvia, oaks with AOD symptoms were first observed in 2017, and the presence of Gibbsiella quercinecans and Brenneria goodwinii in the bark exudate was confirmed. A country-wide survey was initiated to assess the prevalence of oaks with AOD symptoms. In addition, experimental plots were established to monitor the progression of AOD in infected sites. A total of 1,329 forest stands were surveyed; 111 exudate samples were collected and 36 samples were positive for one of both B. goodwinii and G. quercinecans. Larval galleries or other signs of the beetle Agrllus biguttatus were not found in association with AOD symptoms. Four trial plots were established and routinely monitored over a four-year period for AOD symptoms, presence of G. quercinecans and B. goodwinii, and an assessment of fungal species was done. In the trial plots, AOD symptoms peaked in 2019. Presence of the bacteria was not detected in all exudate samples collected regularly over summer from the trial plots. The presence of the bacteria was confirmed only in a few soil samples collected along a transect in one trial plot. One or both bacteria were identified in a few soil and wood samples collected from asymptomatic oak stands. Assessment of fungal species in both symptomatic and healthy trees did not identify significant differences in species composition, soil pH, fine root vitality, and mycorrhization. Environmental factor analysis indicated that precipitation in the previous autumn is related to a higher detection possibility of G. quercinecans and B. goodwinii in exudate samples collected in the following year. Continued monitoring for AOD symptoms, focussing on mature oak trees is required to identify future potential AOD outbreaks in Latvia.
Keywords: Quercus robur; AOD; monitoring; qPCR; phytopathology; environmental factors
O Contexto Dos Estudos Do Clima Urbano Por Meio Do Campo Termo-Higrométrico Em Rondon Do Pará
Authors: Dos Santos Mascarenhas Abraão Levi , Miranda Matheus Martins , Vidal Maria Rita 
Published: June 2024

O desenvolvimento e aprimoramento de técnicas de sensoriamento remoto são cruciais nos estudos de clima urbano, pois a qualidade das áreas urbanas tem se mostrado inadequada para as populações por não levar em consideração as características geoambientais das cidades. Objetiva-se analisar as variações das temperaturas de superfície do solo da cidade de Rondon do Pará, por meio dos estudos de clima urbano, observando os campos térmicos e higrométricos. Para tanto, foram utilizados sensores termais e multiespectrais do satélite Landsat 5, 7 e 8, com escala temporal de 1980 a 2020. Os levantamentos das imagens de satélite foram extraídos do site earthexplore/Nasa, com processamento destas no software Qgis, com a ajuda do plugin SCP. Os principais produtos gerados foram os mapas de temperatura da superfície, SAVI, NDWI e perfil termográfico. Os resultados apontam para médias de 26,6 graus em 1980 e média relativa de 27,8 em 2020, indicando um aumento de temperatura de ±1,2 °C superior. Todos os esforços de mapeamento resultaram em percepções de que a alteração do uso do solo pelos processos urbanos influencia diretamente no campo térmico e higrométrico local (ilhas de calor), que representam pontos de altas temperaturas no mapa termal.
Kai darbuotojai tampa „robotais“: medikų profesinis nuovargis ir su juo siejama psichosocialinės darbo aplinkos rizika pokyčių laikotarpiu
Authors: Toma Jasiukevičiūtė-Zelenko  , Neringa Bagdonaitė  
Published: June 2024

Tikslas – atskleisti asmens sveikatos priežiūros įstaigų (ASPĮ) darbuotojų su profesiniu nuovargiu susijusius psichosocialinės darbo aplinkos ypatumus pokyčių laikotarpiu.
Tyrimo medžiaga ir metodai. Tyrime dalyvavo 7 asmens sveikatos priežiūros įstaigose dirbantys medicinos darbuotojai: 5 moterys ir 2 vyrai, 6 iš jų – gydytojai (-os) (du iš jų dirba ir kaip administracijos darbuotojai – vadovaujamose pozicijose), 1 – slaugytoja. Pagal amžiaus grupes tyrimo dalyviai pasiskirstė taip: 25–35 m. amžiaus grupėje – 1, 35–45 m. amžiaus grupėje – 3, 45–55 m. amžiaus grupėje – 3 dalyviai. Pagal ASPĮ lygmenį tyrimo dalyviai pasiskirstė taip: 4 dirba antrinio lygio sveikatos priežiūros įstaigose, 3 – pirminio lygio sveikatos priežiūros įstaigose; 4 tyrimo dalyviai gyvena didmiesčiuose, 3 – mažesniuose miestuose. Duomenys buvo renkami pasitelkiant pusiau struktūruoto interviu metodą. Duomenys analizuoti taikant V. Braun ir V. Clarke teminės analizės metodą.
Rezultatai ir išvados. Tyrime dalyvavę ASPĮ medicinos darbuotojai nurodo įvairius profesinio nuovargio pasireiškimo fizinius (somatiniai simptomai, nuolatiniai peršalimai, galvos skausmai, sąmonės netekimo epizodai) ir psichikos sveikatos požymius (nerimas ir nemiga, negebėjimas susikaupti ir atminties problemos, atitolimo nuo žmonių, tuštumos ir beprasmybės jausmai, tapatumo sutrikimai, didesnis poreikis vartoti psichoaktyvias medžiagas), kurie turi žalingą poveikį jų asmeninei ir profesinei gerovei. ASPĮ darbuotojų profesinio nuovargio patyrimui didelę reikšmę turi tokie psichosocialiniai rizikos veiksniai kaip: per didelis bendras darbo krūvis, per didelis darbo tempas, mažai galimybių kontroliuoti savo darbą, neaiškios darbuotojų funkcijos ir darbo tvarka, sudėtingas darbo turinys. Siekiant suvaldyti profesinio nuovargio problemą ASPĮ darbuotojų darbo aplinkoje, svarbu įgyvendinti psichosocialinės darbo aplinkos pokyčius, apimančius darbo krūvio mažinimą, darbdavio iniciatyvas mažinant psichosocialinę riziką, pasitelkiant ne finansines skatinimo priemones bei didinant reabilitacijos paslaugų prieinamumą.
Analysis of the effectiveness of management in the field of alternative energy, taking into account its territorial distribution
Authors: Шарифуллин Д.В. , Ярош О.Б. 
Published: June 2024

В статье осуществлен анализ управления в сфере альтернативной энергетики с учетом ее территориального размещения. Рассматривается эффективность управления в данной области в России, с акцентом на сферу альтернативной энергетики. Основной целью является оценка эффективности управления, учитывая территориальное распределение. Теоретическое значение работы проявляется в разработке авторской интерпретации критериального подхода и специализированного набора критериев для оценки эффективности управления в сфере альтернативной энергетики с учетом территориального размещения. Сформулированы рекомендации для повышения эффективности управления в данной сфере в России. Результаты исследования могут быть использованы для анализа и оптимизации научных задач в области альтернативной энергетики, менеджмента и экономики.
The article analyzes management in the field of alternative energy, taking into account its territorial location. The effectiveness of management in this area in Russia is considered, with an emphasis on the field of alternative energy. The main goal is to assess the effectiveness of management, taking into account the territorial distribution. The theoretical significance of the work is manifested in the development of the author’s interpretation of the criterion approach and a specialized set of criteria for evaluating the effectiveness of management in the field of alternative energy, taking into account territorial location. The practical significance of the study lies in the formation of recommendations for improving the effectiveness of management in this area in Russia. The results of the research can be used to analyze and optimize scientific tasks in the field of alternative energy, management and economics.
On some methods of change management in russian construction companies
Authors: Максимов М.И. , Карапетян Л.О. 
Published: June 2024

Способность компаний выживать в текущих условиях постоянных изменений является первостепенной для более долговременного существования и развития. Возникает необходимость в управлении изменениями. На российском строительном рынке наблюдается постепенный рост, государство делает упор на цифровизацию отрасли. При этом есть негативная тенденция: дефицит рабочей силы, который возник после введенных санкций, связанных с СВО. Возникает задача привлекать и удерживать персонал, поддерживать лояльность и развивать корпоративную культуру через грамотные, последовательные изменения. Важно следовать мировому тренду развития строительной индустрии, а именно внедрению концепции единой информационной среды совместно с технологией BIM, так как современная методология имеет целый ряд преимуществ перед традиционным ведением бизнес-процессов. Сутью изменения является улучшение производительности компании, облегчение организации строительных проектов на всех этапах их жизненного цикла. При этом российские строительные компании достаточно консервативны и тяжело воспринимают изменения, потому важно говорить о том, какую выгоду смогут привнести изменения, рассмотреть, какие барьеры могут быть на пути и как их можно преодолевать.
The ability of companies to survive in the current environment of constant change is essential for long term existence and development. There is a need for change management. There is a gradual growth in the Russian construction market, with the government focusing on digitalization of the industry. At the same time, there is a negative trend: labor shortage, which emerged after the imposed sanctions related to the special military operation. The task arises to attract and retain personnel, maintain loyalty and develop corporate culture through competent, consistent changes. It is important to follow the global trend in the construction industry, namely the introduction of the concept of a common data environment together with BIM technology, as modern methodology has a number of advantages over traditional business processes. The core of the change is to improve the company’s productivity, facilitating the organization of construction projects at all stages of their life cycle. At the same time, Russian construction companies are quite conservative and hard to accept changes, so it is important to talk about what benefits can bring changes, to consider what barriers may be in the way and how they can be overcome.
ANÁLISE DO USO DA DROGA PSICODÉLICA CETAMINA PARA TRATAMENTO DE DEPRESSÃO EM IDOSOS: UMA REVISÃO DE LITERATURA
Authors: Ribeiro Mariana Gianisella , Gomes Ana Clara Leão , Paixão Rebeca Bressan 
Published: June 2024

Introdução: O envelhecimento populacional apresenta um perfil de morbimortalidade inusitado, com a redução das doenças infectocontagiosas e aumento de doenças crônico-degenerativas, como a depressão, que atinge cerca de 30% dos idosos. A depressão, trata-se de uma condição complexa, influenciada por fatores biológicos, psicológicos e sociais. Embora existam mais de oito classes de antidepressivos no mercado, apenas 30 a 35% dos pacientes respondem adequadamente ao tratamento. Um desses medicamentos é a cetamina, tradicionalmente utilizada como anestésico, que tem demonstrado eficácia em quadros de depressão resistente. Estudos sugerem que sua ação sobre neurotransmissores, como o glutamato, é capaz de mitigar os sintomas depressivos ao bloquear receptores N-metil-D-aspartato (NMDA) e ativar outros que estimulam a neuroplasticidade das sinapses, como α-amino-3-hidroxi-5-metilisoxazol-4-acidoprpionico (AMPA). O presente trabalho visa sintetizar achados sobre o uso da cetamina no tratamento de depressão em idosos através de revisão de literatura. Objetivo: Compreender os efeitos do uso de cetamina em idosos para tratamento de depressão. Metodologia: Revisão de literatura realizada no banco de dados Pubmed, Scielo, Lilacs em artigos que cumpriram os critérios de inclusão, exclusão e descritores. Resultados: Estudos indicam melhorias significativas após 8 infusões iniciais de cetamina, destacando benefícios como bem-estar psicológico e redução de ideias suicidas em pacientes acima de 60 anos. Embora sua eficácia tenha sido observada em idosos, comparações com adultos mais jovens revelaram maior responsividade nestes últimos quando inicia o tratamento precocemente. A cetamina também se mostrou eficaz no tratamento da depressão catatônica em idosos, apresentando resultados positivos como alternativa à terapia eletroconvulsiva em situações como a pandemia e comorbidades restritivas. Pesquisas com spray nasal de cetamina na França mostraram redução na pontuação da Escala de Depressão de Montgomery-Åsberg, porém a dose ideal para idosos, nesse estudo, não foi definida. Já em outro estudo sobre a dosagem em veteranos militares idosos indicam maior probabilidade de segurança e eficácia de resposta com cetamina 0,5mg, e essa tendo melhor probabilidade de tratamento em comparação ao midazolam. Revisões ressaltam a escassez de literatura sobre este assunto, sendo isso uma limitação, apesar de resultados promissores até o momento. Conclusão: A cetamina é promissora para a depressão resistente em idosos, embora haja resultados incertos. Seu uso demonstra rápida remissão, mas desafios, como definir a dose ideal, forma de administração e compreender efeitos a longo prazo, persistem. Portanto, são necessárias pesquisas adicionais para orientações mais específicas para prática clínica, visando aprimorar o tratamento da depressão em idosos.