bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic accuracy of pre‐treatment biopsy for grading soft tissue sarcomas in dogs
Authors: Perry J. A. , Culp W. T. N. , Dailey D. D. , Eickhoff J. C. , Kamstock D. A. , Thamm D. H. 
Published: May 2012

AbstractHistologic grade is an important prognostic factor for both local recurrence and metastatic potential with canine soft tissue sarcoma (STS). Pre‐treatment biopsy with identification of tumour grade may aid in prognostication and determination of surgical margins necessary for local control. The purpose of this study was to evaluate the grading accuracy of various pre‐treatment biopsy techniques (wedge, punch, needle‐core) forSTSin dogs. Medical records of 68 dogs diagnosed with aSTSvia pre‐treatment biopsy and confirmed by excisional biopsy were evaluated. The concordance in grade between excisional and pre‐treatment biopsies was 59%. Of the 41% that lacked concordance, 29% of pre‐treatment biopsies underestimated and 12% overestimated grade. The method of pre‐treatment biopsy did not significantly effect grade concordance. Based on these data, needle‐core biopsy appears to be similar in accuracy compared to open biopsy, however, grading determined by pre‐treatment biopsy in general should be interpreted with caution.
Effect of IntraperitonealPERIDAN™Concentrate Adhesion Reduction Device on Clinical Findings, Infection, and Tissue Healing in an Adult Horse Jejunojejunostomy Model
Authors: Morello Samantha , Southwood Louise L. , Engiles Julie , Slack JoAnn , Crack Aaron , Springate Christopher M. K. 
Published: May 2012

ObjectiveTo evaluate the effect ofPERIDAN™Concentrate on clinical findings, infection, and tissue healing in adult horses undergoing celiotomy and jejunojejunostomy.Study DesignBlock randomized blinded experimentalin vivostudy.AnimalsAdult horses (n = 12).MethodsHorses had jejunojejunostomy at 2 sites and were administered 5Lof dilutedPERIDAN™Concentrate (6 horses) orLactatedRinger'sInjection (LRS) control intraperitoneally (6 horses) before body wall closure. Postoperative monitoring comprised physical examinations, serial hematology, coagulation and chemistry panels, and ultrasonographic examination. Horses were euthanatized 10 days postoperatively. Anastomoses and linea alba incisions were tested for mechanical strength; and tissue healing, inflammation, and infection were assessed by histological evaluation. Data were analyzed using a mixed modelANOVA. Level of significance wasP< .05.ResultsNo physical examination differences were observed between groups. Statistically significant differences were observed in leukocyte and neutrophil counts, prothrombin time, antithrombinIIIactivity, intestinal bursting pressures, and histologic healing grade in the mid region of the linea alba. These differences were minimal, and of no observable clinical significance. Other blood variable and histologic differences between groups were not significant.ConclusionsPERIDAN™Concentrate was safely administered intraperitoneally to healthy horses undergoing celiotomy and anastomosis.
Intraoperative cell salvage in radical prostatectomy does not appear to increase long‐term biochemical recurrence, metastases, or mortality
Authors: Raval Jay S. , Nelson Joel B. , Woldemichael Elen , Triulzi Darrell J. 
Published: May 2012

BACKGROUND: Blood management strategies help to conserve allogeneic red blood cells, a finite resource. Intraoperative cell salvage (ICS) is an effective method of allogeneic avoidance. However, concerns persist about the safety of ICS in surgical oncology cases, including radical prostatectomy (RP). Previous findings do not support these concerns. We hypothesized that ICS would not increase rates of long‐term prostate cancer recurrence characterized by biochemical failure, disease dissemination, or mortality.STUDY DESIGN AND METHODS: Consecutive patients undergoing RP by a single urologist over two 3‐month periods 1 year apart were analyzed retrospectively. Patients in the first period had preoperative autologous donation (PAD) but not ICS (PAD group), whereas those in the second period had ICS only (ICS group). Variables assessed included patient demographics, prostate‐specific antigen levels at surgery and end of follow‐up, clinical stage, operative time, surgical margin status, pathologic stage and grade, Gleason score sum, length of hospital stay, biochemical recurrence, metastases, and mortality.RESULTS: A total of 116 consecutive patients were analyzed. Of these, 32 patients in the PAD group and 42 patients in the ICS group had follow‐up of at least 4.75 years. There was a significantly higher rate of biochemical failure (34.4% vs. 9.5%; p = 0.02) and metastases (12.5% vs. 0%; p = 0.03) in the PAD group versus the ICS group; there was no significant difference in mortality (9.4% vs. 0%; p = 0.08).CONCLUSION: ICS appears to be a safe and effective method of allogeneic blood conservation in patients undergoing RP. The findings suggest that there is no increased risk of biochemical failure, disease dissemination, or mortality at 5 years post‐RP as a result of ICS use.
Analysis of stored and transplanted cord blood units from KoreaCORD: reappraisal of banking guidelines and selection strategy
Authors: Lee Young‐Ho , Kwon Young‐Hee , Hwang Kyoujung , Jun Hyunju , Lee Mi‐Ae , Jang Hyung‐In , Nah Jung‐Hwa , Koo Hong‐Hoe , Hwang Tai‐Ju 
Published: May 2012

BACKGROUND: We analyzed the characteristics of stored and transplanted cord blood (CB) units from the Korean network for public CB donation (KoreaCORD) to reassess the banking guidelines and optimize CB selection based on cell dose and human leukocyte antigen (HLA) mismatching.STUDY DESIGN AND METHODS: We retrospectively reviewed data, with regard to total nucleated cell (TNC) count and HLA match in the KoreaCORD registry from August 2001 to December 2010.RESULTS: A total of 21,914 CB units have been registered, of which 904 units (4.1%) contained less than 5 × 108 TNCs, which did not meet the present storage criteria for public CB banking in Korea. Although the proportion of stored CBs providing TNC of 5 × 108 to 7.9 × 108 was 45.7%, only 22.0% of all transplanted CBs were derived from these stored CBs. In the single CB transplantation setting, 79% (85/108) of CB units provided 4 × 107 TNCs/kg or more in the transplanted one‐mismatch (1‐MM) CB units and 51% (19/37) of CBs provided 6 × 107 TNCs/kg or more in the transplanted 2‐MM CB units.CONCLUSIONS: The minimal requirement of TNCs for banking of CB units for public banking should be evaluated and increased to support the selection of CB units with higher cell doses, especially for use in the 1‐ and 2‐MM transplant settings.
Early‐Mid Term Follow‐Up Results of Percutaneous Closure of the Interatrial Septal Defects with Occlutech Figulla Devices: A Single Center Experience
Authors: AYTEMIR KUDRET , OTO ALI , ÖZKUTLU SÜHEYLA , KAYA ERGÜN BARIŞ , CANPOLAT UĞUR , YORGUN HIKMET , ŞAHINER LEVENT , KABAKÇI GIRAY 
Published: May 2012

Background:

Percutaneous closure of secundum type atrial septal defect (ASD) and patent foramen ovale (PFO) has gained widespread use in recent years. Herein, we evaluated the safety and efficacy of the Occlutech® Figulla devices for PFO and ASD closure in a reference tertiary center.
Methods:

All 143 patients (46.9% male, mean age 39.3 ± 12.2 years) who underwent transcatheter PFO (n = 85) and ASD (n = 58) closure with Occlutech® Figulla devices between February 2009 and October 2011 were included in this study. An echocardiographic follow‐up examination was performed at the 1st, 6th, and 12th month visits.
Results:

The devices were successfully implanted in all 143 patients (100%). In‐hospital periprocedural complications were device embolization (0.7%; 1 ASD patient), atrial fibrillation (1.4%; 1 ASD and 1 PFO patients), supraventricular tachycardia (0.7%; 1 PFO patient), and vascular access hematoma (0.7%; 1 ASD patient). Among ASD patients, 2 patients had trivial (jet width <1 mm in diameter) and 1 patient had small (1–2 mm) residual shunts before hospital discharge, which disappeared after the 6‐month visit. During the mean 15.4 ± 9.6 months follow‐up, all patients were asymptomatic and no ischemic stroke, cardiac perforation, device erosion, embolization, thrombus formation, or malposition of the device was observed.
Conclusions:

Percutaneous PFO and secundum type ASD closure with the novel Occlutech® Figulla Occluder devices without left atrial central pin and with significantly reduced meshwork was safe, feasible, and effective. (J Interven Cardiol 2012;25:375–381)
Epidemiological Study of Complementary and Alternative Medicine (CAM) Use for the Improvement of Sexual Function in Young Korean Men: The Korean Internet Sexuality Survey (KISS), Part II
Authors: Choi Woo Suk , Song Sang Hoon , Son Hwancheol 
Published: May 2012

ABSTRACT

Introduction
Few studies have been conducted on complementary and alternative medicine (CAM) for improving sexual function.

Aims
We investigate CAM use for improving sexual function and propose a model explaining what leads to CAM use.

Methods
Participants between 20 and 59 years old were recruited from an Internet research panel representing young Korean men. Participants were asked to complete questionnaires on demographic details, attitude toward sexual activity, sexual function, CAM use, and desire to use CAM. Subjects were classified into three subgroups. Men who use CAM, men who desire but do not actually use CAM, and men who neither use nor desire to use CAM were allocated to groups A (actual user), P (potential user), and N (nonuser), respectively.

Main Outcome Measures
CAM use, desire to use CAM, questionnaires on self-reported sexual function and attitude toward sexual activity, International Index of Erectile Function-5, Premature Ejaculation Diagnostic Tool, and Short Form 36 Health Survey (SF-36).

Results
Among 443 subjects with a mean age of 39.2 ± 10.2 years, 49 (11.1%) used CAM for improving sexual function (group A). Dietary supplements were most commonly used. Overall mean satisfaction for the used CAM was 55.5 ± 24.2%. There were 192 (43.3%) men who desired but did not use CAM (group P). According to multivariate analysis, risk factors for desiring CAM included drinking (odds ratio [OR] = 2.24, 95% confidence interval [CI] = 1.28–3.91), regarding sex a very important part of life (OR = 2.16; 95% CI = 1.41–4.09), self-reported erectile dysfunction (ED) (OR = 5.08; 95% CI = 1.60–16.1), and self-reported premature ejaculation (PE) (OR = 3.34; 95% CI = 1.65–6.76). Risk factors for actual CAM use included smoking (OR = 2.49; 95% CI = 1.11–5.61), a strongly positive attitude toward sexual activity (OR = 3.77; 95% CI = 1.42–9.99), low role emotion points on the SF-36 (OR = 0.98; 95% CI = 0.97–0.99), and self-reported non-PE (OR = 0.22; 95% CI = 0.06–0.73).

Conclusions
Smoking, drinking, self-reported ED, self-reported PE, attitude toward sexual activity, and emotional problems play roles in making decisions concerning CAM use.
Phenotypic and allelic profile of ABO and Rhésus D blood group system among blood donor in Antananarivo
Authors: Randriamanantany Z. A. , Rajaonatahina D. H. , Razafimanantsoa F. E. , Rasamindrakotroka M. T. , Andriamahenina R. , Rasoarilalamanarivo F. B. , Hanitriniala S. P. , Herisoa F. R. , Rasamindrakotroka A. , Rakoto Alson O. A. 
Published: May 2012

SummaryThis study assessed the phenotypic and allelic profiles of ABO and Rhesus D blood group system among first time blood donors at the National Centre of Blood Supply of Antananarivo. We collected through this retrospective study all data registered during 7 years of practice (from 2003 to 2009). Age and sex were analysed with the result of ABO and RhD screening. They were tested both with Beth Vincent and Simonin tests which were performed in a plate, by using commercial monoclonal antibody (Diaclone® et Eryclone®), and home‐made red cells tests. The Rh D was performed with the same commercial kits. The frequencies of alleles were calculated by using Bernstein method. Data about 45 857 donors were obtained. A male predominance (80.46%) was found and most of our donors were aged <40 (74.92%). 98.90% of the donors were Rh D positive. Phenotypic distribution of each ABO antigen was, respectively, 22.61, 29.66, 6.13 and 41.60% for A, B, AB and O antigen. Allelic frequencies of A, B and O were 0.1559, 0.1987 and 0.6454. These results confirmed the fact that Madagascan population had admixed ethnic origin.
Estimation of methane emission rates from a rice paddy field using a naturally ventilated tunnel
Authors: Kato Futoshi , Inoue Naoto , Kasuga Shigemitsu , Yoshikawa Anna , Hayakawa Tomokazu , Murata Haruka , Kasajima Shinya 
Published: May 2012

AbstractA novel system for monitoring methane emission from a flooded paddy field was developed in order to quantify the greenhouse gas emission in near‐natural conditions. A paddy field planted with rice was covered by a semi‐open vinyl tunnel (1.8 × 10 × 2.5 m), and the methane concentrations inside and outside the tunnel were measured continuously from the booting stage to the ripening stage (August–September) using a methane gas detector. Methane emission rates were calculated on an hourly basis from the differences between the internal and external methane concentrations and the natural diffusion rates determined using a tracer gas method. The results indicated that the paddy field emitted 0.41–1.32 g methane m−2 day−1 during the two growth stages. The vinyl tunnel had no adverse effect on the growth and yield of rice plants inside. Despite the disadvantage of non‐accurate estimation under windy conditions, the technique is considered to be of potential value for evaluating methane emissions from a flooded paddy field.
The Capitalization of Area Payments into Farmland Rents: Micro Evidence from the New EU Member States
Authors: Ciaian Pavel , Kancs d’Artis 
Published: May 2012

This study investigates the impact of the Single Area Payment Scheme (SAPS) on farmland rental rates in the New EU Member States. Using a unique set of farm level panel data with 20,930 observations for 2004 and 2005 we are able to control for important sources of endogeneity. According to our results, the SAPS has a positive and statistically significant impact on land rents in the EU. However, the estimated incidence is smaller than predicted theoretically. Land rents capture only 19 cents of the marginal SAPS EUR, and around 10% of the SAPS benefit nonfarming landowners through higher farmland rental prices. As the share of rented land is higher in corporate farms than individual ones, family farms benefit more from the SAPS than corporate farms do.Dans la présente étude, nous avons étudié les répercussions du Régime de paiement unique à la surface (RPUS) sur les taux de location de terres agricoles dans les nouveaux États membres de l’Union européenne. À l’aide d’un ensemble unique de données de panel sur les exploitations agricoles renfermant quelque 20 930 observations recueillies en 2004 et en 2005, nous avons pu maîtriser des sources d’endogénéité importantes. Nos résultats montrent que le RPUS a des répercussions positives et statistiquement significatives sur les loyers fonciers dans les pays de l’Union européenne. L’incidence estimative est toutefois inférieure à la valeur prévue théoriquement. Les loyers fonciers ne s’emparent que de 19 cents l’euro du RPUS marginal, et près de 10 p. 100 du RPUS profitent aux propriétaires fonciers non exploitants en raison des prix de location de terres plus élevés. Comme la part des terres louées est plus élevée dans le cas des fermes constituées en société que dans le cas des fermes individuelles, les fermes familiales profitent davantage du RPUS.
Correlation functions for extended mass galaxy clusters
Authors: Iqbal Naseer , Ahmad Naveel , Hamid Mubashir , Masood Tabasum 
Published: May 2012

Abstract
The phenomenon of clustering of galaxies on the basis of correlation functions in an expanding Universe is studied by using equation of state, taking gravitational interaction between galaxies of extended nature into consideration. The partial differential equation for the extended mass structures of a two-point correlation function developed earlier by Iqbal, Ahmad & Khan is studied on the basis of assigned boundary conditions. The solution for the correlation function for extended structures satisfies the basic boundary conditions, which seem to be sufficient for understanding the phenomena, and provides a new insight into the gravitational clustering problem for extended mass structures.
Management of Giant Cell Tumor of Bone: Computerized Tomography Based Selection Strategy and Approaching the Lesion Through the Site of Cortical Break
Authors: Puthoor Dominic K , Puthezhath Kishore 
Published: May 2012

ObjectiveA retrospective study was carried out in patients with giant cell tumor of bone to compare the functional and radiographic outcome of curettage and bone grafting using a novel CT based selection strategy to that of patients of a similar age treated with anatomic/standard curettage and bone grafting.MethodsCurettage and bone grafting after CT classification was performed in 31 patients and curettage and bone grafting without CT classification in 20. The surgical approach for curettage in the CT classified group of patients was through the site of the cortical break, irrespective of the standard approach to the particular region of bone involved. The aim of this approach was to achieve wide excision of the possibly involved soft tissue.ResultsAt similar duration of follow up (72 months) in patients with a similar mean age (33 years), Musculoskeletal Tumor Society (MSTS) scores for CT classified patients were similar to those of patients who had undergone standard curettage. However, the postoperative recurrence rate in the CT classified group was significantly less (12.9%) than in the non‐CT classified group.ConclusionA CT based selection strategy is a valid preoperative tool for evaluation of giant cell tumor. Further, for curettage these lesions are better approached through the site of cortical break, irrespective of standard approaches, so that adequate soft tissue clearance can be achieved.
Factors Influencing Segmental Lumbar Lordosis After Lateral Transpsoas Interbody Fusion
Authors: Kepler Christopher K. , Huang Russel C , Sharma Amit K , Meredith Dennis S , Metitiri Ochuko , Sama Andrew A , Girardi Federico P , Cammisa Frank P 
Published: May 2012

ObjectiveAlthough contributions to sagittal alignment have been characterized for anterior, posterior and transforaminal lumbar interbody fusion, sagittal alignment after lateral transpsoas interbody fusion (LTIF) has not yet been characterized. This study examined the ability of LTIF to restore lumbar lordosis and identified factors associated with change in sagittal alignment.MethodsTwenty‐nine patients and 67 levels were studied. Segmental lordosis, anterior‐posterior cage position, and cage obliquity were measured on preoperative and postoperative radiographs and CT scans. Change in sagittal alignment was analyzed with respect to demographic information and measures of cage position and obliquity to identify factors associated with segmental alignment change.ResultsMean lordosis increased 3.7° at instrumented segments, increasing from 4.1° preoperatively to 7.8° postoperatively. Although increases at each level were significant, there were no significant differences between levels. Lordosis increase was inversely‐associated with preoperative lordosis; levels with the least preoperative lordosis gained the most lordosis. Cage obliquity and height were not significantly associated with lordosis change. Anterior cage placement resulted in the largest lordosis gain (+7.4°/level) while posterior placement was prokyphotic (−1.2°/level). There were no significant associations with age, sex or body mass index.ConclusionAnteroposterior cage placement is an important intraoperative determinant of postoperative alignment; anterior placement results in greater lordosis while middle/posterior placement has a minimal effect on sagittal alignment.
Global Governance and Integrative Balancing: EU Efforts to Respond to the Global Challenge
Authors: Ágh Attila 
Published: May 2012

AbstractIn the early 21st century globalisation has radically transformed the whole world. In the rapidly globalising world the main issue for the EU is globalisation‐cum‐regionalisation, namely to increase policy cooperation with its own neighbourhood to strengthen its global position and to avoid systemic failure in its partner countries by offering them a win‐win game through regional organisations. Globalisation has unleashed the process of regionalisation at various levels, so restructuring the political space around the globe. New territorial units have been organised in order to be able to withstand the pressure of globalisation, and to be more effective in the global competition that has also generated the need for global governance. The basic principle in the recent regionalisation efforts by the EU is ‘integrative balancing’, empowering unequal external partners through meaningful cooperation. In this spirit the EU has recently transformed its global policy in both aspects of globalisation‐cum‐regionalisation. It has accelerated common institution building with neighbouring states. The EU has also established an active cooperation framework with the newly emerging global powers as ‘strategic partners’. Altogether, the European Council concluded in October 2010 that ‘wider governance reform should be delivered’ in the EU’s global policy.1Policy Implications
The rise of the multilateral world order requires a clear EU strategy for the regionalisation of its own neighbourhood. The increasing tensions in both the southern and eastern rims have also been pushing the EU in this direction.
The EU regionalisation strategy needs an institutional separation of the southern and the eastern mega‐regions, given the basic differences between them concerning ‘European perspectives’, that is, their different opportunities for EU membership.
There can be no gap between the polity and policy approaches in EU regionalisation. This means that the EU cannot extend its regulative regimes to neighbouring regions without building proper common institutions with the partner states concerned in those policy fields, in which common policies have been intensified.
Integrative balancing mechanisms have to be invented and implemented by the EU in order to upgrade its partner states instead of simply imposing strict conditionalities upon them.