bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors Associated with Peritoneal Dialysis Catheter Survival: A 9-Year Single-Center Study in 315 Patients
Authors: Singh Namita , Davidson Ingemar , Minhajuddin Abu , Gieser Steven , Nurenberg Michael , Saxena Ramesh 
Published: November 2010

Purpose To review the peritoneal dialysis (PD) catheter outcomes at our center and assess factors affecting catheter survival. Methods We carried out a retrospective study on 315 patients who had their first PD catheter placed between January 2001 and September 2009 at the UT Southwestern/DaVita Peritoneal Dialysis Clinic at Dallas, Texas. Medical records were reviewed for demographic and clinical information of the patients. The primary end point of the study was PD catheter failure, defined as removal of a dysfunctional PD catheter due to catheter-related complications. Catheter survival was estimated using the Kaplan-Meier method. Cox proportional hazard regression model was used to identify factors that are independently associated with catheter survival. Results The mean age of the patients was 49.7 ± 29 yrs. The study population included 54.6% females, 42.5% African American, 27.9% Caucasian and 22.9% Hispanic patients. Diabetes was the primary etiology of end-stage renal disease in 43.2% of patients. More than 90% of patients had one or more co-morbidities, and 57.5% had previous abdominal surgery. The mean BMI for the group was 28.6 ± 13.8 kg/m2. Less than a quarter of the patients (24.1%) had non-infectious/mechanical catheter problems. Overall PD catheter survival rates over 12, 24 and 36 months were 92.9%, 91.9% and 91.1%, respectively. PD catheter-related non-infectious problem was the only independent variable that was significantly associated with catheter survival (hazard ratio 22.467; 95% CI 6.665–75.732). No significant association was observed between the PD catheter survival and other risk factors including age, body mass index (BMI), diabetic status, co-morbidities, previous abdominal surgeries or infections. Conclusions Our study shows an excellent 3-yr PD catheter survival (91.1%). Only PD catheter-related non-infectious problems are significantly associated with catheter failure. Other factors such as age, gender, race, BMI, diabetic status, co-morbidities, previous abdominal surgeries, peritoneal infections or exit site/tunnel infections were not found to affect the PD catheter survival and should not be considered barriers to PD initiation.
Double-Lumen Central Venous Port Catheters: Simultaneous Application for Chemotherapy and Parenteral Nutrition in Cancer Patients
Authors: Teichgräber Ulf K.M. , Nagel Sebastian N. , Kausche Stephan , Streitparth Florian , Hee Cho Chie 
Published: November 2010

Purpose This study was designed to evaluate the clinical benefit of low-profile double-lumen port catheters in patients receiving simultaneous chemotherapy and parenteral nutrition (PN). Potential advantages, complications, and the durations of simultaneous and single use of the catheter were assessed. Methods At a university teaching hospital, 10 patients received a double-lumen port catheter (5 men, 5 women; mean age 61.5 ± 12 years). All port implantations were performed under ultrasonographic and fluoroscopic guidance in the radiologic interventional suite. Procedure-related immediate, early, and late complications were recorded until removal of the device, patient's death, or completion of follow-up period. Application times and durations for chemotherapy or PN were determined. Results No immediate complications were observed. First use of the port system for chemotherapy was within 12 days (± 25 days, range 0–84 days) and within 17 hours (± 22 hours, range 0–72 hours) for PN on average. During the application of PN, no delay or interruption of chemotherapy was observed. The port catheter was used for the simultaneous application of chemotherapy and PN for a total of 1,216 hours. One port catheter was removed after 30 days due to suspected port infection. Conclusion Central venous double-lumen port systems as a therapeutic option in patients requiring chemotherapy and PN can increase safety during those simultaneous applications, while offering improved patient comfort.
Endovascular Intervention for Central Venous Cannulation in Patients with Vascular Occlusion after Previous Catheterization
Authors: Pikwer Andreas , Acosta Stefan , Kölbel Tilo , Åkeson Jonas 
Published: November 2010

Objectives This study was designed to assess endovascular intervention for central venous cannulation in patients with vascular occlusion after previous catheterization. Methods Patients referred for endovascular management of central venous occlusion during a 42-month period were identified from a regional endovascular database, providing prospective information on techniques and clinical outcome. Corresponding patient records, angiograms, and radiographic reports were analyzed retrospectively. Results Sixteen patients aged 48 years (range 0.5–76), including 11 females, were included. All patients but 1 had had multiple central venous catheters with a median total indwelling time of 37 months. Eleven patients cannulated for hemodialysis had had significantly fewer individual catheters inserted compared with 5 patients cannulated for nutritional support (mean 3.6 vs. 10.2, p<0.001) before endovascular intervention. Preoperative imaging by magnetic resonance tomography (MRT) in 8 patients, computed tomography (CT) venography in 3, conventional angiography in 6, and/or ultrasonography in 8, verified 15 brachiocephalic, 13 internal jugular, 3 superior caval, and/or 3 subclavian venous occlusions. Patients were subjected to recanalization (n=2), recanalization and percutaneous transluminal angioplasty (n=5), or stenting for vena cava superior syndrome (n=1) prior to catheter insertion. The remaining 8 patients were cannulated by avoiding the occluded route. Conclusions Central venous occlusion occurs particularly in patients under hemodialysis and with a history of multiple central venous catheterizations with large-diameter catheters and/or long total indwelling time periods. Patients with central venous occlusion verified by CT or MRT venography and need for central venous access should be referred for endovascular intervention.
Indication and Usage of Peripheral Venous Catheters Inserted in Adult Patients during Emergency Care
Authors: Göransson Katarina E. , Johansson Eva 
Published: November 2010

Purpose The aim of this study was to identify the underlying decisions taken regarding the insertion of prehospital peripheral venous catheters in adult patients and, additionally, to ascertain peripheral venous catheter insertion rate and explore prehospital and hospital (within 24 hours of insertion) pharmaceutical treatment via peripheral venous catheters. Method This cross-sectional study gathered data through a study-specific questionnaire and patient record auditing. We distributed a study-specific questionnaire to be completed by ambulance crews, and carried out patient record auditing for 345 patients (median age 64 years, range 18–97 years) arriving at the emergency department at a Swedish level-1 trauma center in October 2008. Results Of 135 patients (39%) arriving at the emergency department with a peripheral venous catheter, 94 (70%) had received the device because the ambulance crews intended to use it for intravenous therapeutics (of which analgesics, intravenous fluids, and psycholeptics were most frequently used). In 30 patients (22%), the prehospital inserted device was not used by the ambulance crews or at hospital within 24 hours. The corresponding rate of unused peripheral venous catheters inserted in patients after arrival at the hospital was 35%. Conclusions We found that the main reason for the ambulance staff to insert a peripheral venous catheter in a prehospital setting was that they intended to use the device. Further, the rate of unused peripheral venous catheters was lower among prehospital peripheral venous catheters than hospital.
Venae Comitantes as a Potential Vascular Resource to Create Native Arteriovenous Fistulae
Authors: Morale Walter , Patanè Domenico , Incardona Concetta , Seminara Giuseppe , Messina Martina , Malfa Pierantonio , L'Anfusa Giuseppe , D'Arrigo Giuseppe , Spanti Demetrio , Mandalà Maria Luisa , Di Landro Domenico 
Published: November 2010

Purpose The arteriovenous fistula (AVF) represents the gold standard for hemodialysis (HD) vascular access. In some critical cases, use of the deep venous circle may represent an alternative approach and venae comitantes could be employed for this purpose. Methods Sixty patients with chronic renal failure in which the deep venous circle was used to create an AVF were identified; of the 48 who had a direct anastomosis between the brachial artery and vena comitans, 42 had a long-term follow-up (mean follow-up 59 weeks), while six were lost to follow-up. Results Immediate success (patency and palpable thrill) was achieved in 88% of cases (primary and early failure 12%). Primary accessibility rate was 62%, while 11 patients required a second surgical approach to make the vein accessible to needling. Secondary accessibility rate of 71% was due to surgical revisions. In the 80–week observation period, the complication rate was 10% with irreversible loss of the AVF in all these cases. Cumulative patency was 71% at the 80th week. Including all 42 patients, technical and functional success rate, defined as vein accessibility to needling and chance of an adequate HD treatment, was 62%. Conclusions AVF employing venae comitantes may represent a suitable alternative in the absence of other vascular accesses for HD.
Comparison of Clinical Effectiveness between Surgical and Endovascular Treatment for Thrombotic Obstruction in Hemodialysis Access
Authors: Ito Yutaka , Sato Takashi , Okada Rei , Nakamura Nobumasa , Kimura Keiko , Takahashi Ryo , Miwa Naofumi , Sakurai Hiroshi , Tsuboi Masato , Kasuga Hirotake 
Published: November 2010

Purpose Endovascular treatment (ET) is widely used for thrombotic complications of vascular access (VA) for hemodialysis. We evaluated the effectiveness of both ET and surgical interventions for thrombotic complications. Methods We studied 533 patients who underwent surgical procedures (a total of 879 procedures) and 54 patients who received ET (a total of 156 procedures) for VA obstruction (endovascular group; group 1). The 533 patients who underwent surgical procedures were further divided into two groups: the surgical balloon-angioplasty group (the thrombus was surgically removed and the stenotic lesions were dilated by balloon angioplasty; 189 procedures; group 2) and the surgical repair group (the stenotic lesions were bypassed with additional graft diversion or creation of a new access; 690 procedures; group 3). The three groups were evaluated for VA patency. Results Using the Kaplan-Meier method, the 2–yr patency for groups 1, 2, and 3 were 11.1%, 11.5%, and 34.0% (p<0.0001). The 2–yr patency rates in patients in whom arteriovenous grafts were used were 5.9% (group 1), 9.2% (group 2), and 22.8% (group 3) (p<0.0001), whereas in patients with arteriovenous fisutulae they were 33.7% (group 1), 35.7% (group 2), and 59.8% (group 3) (p=0.0005). Conclusions A surgical approach may cause difficulty in creating a new VA, because useful access vessels are limited. Our results indicate surgical balloon-angioplasty and ET provide the same patency. ET is less invasive and can be repeated, which makes it beneficial for the patients. We concluded ET could be considered as the first-line treatment for thrombotic complications.
Augmented Balloon-assisted Maturation (aBAM) for Nonmaturing Dialysis Arteriovenous Fistula
Authors: Samett Evan J. , Hastie Joshua , Chopra Paramjit “Romi” , Pradhan Sujit , Ahmad Iftikhar , Chiramel Terence , Joseph Reginald 
Published: November 2010

Purpose The surgically placed dialysis arteriovenous fistula (AVF) is considered by the Kidney Disease Outcomes Quality Initiative (KDOQI) and the Fistula First Breakthrough Initiative to be the ideal choice for hemodialysis access. A significant number of newly placed AVFs either slowly or never adequately mature sufficiently to provide for adequate dialysis. The balloon-assisted maturation (BAM) procedure utilizes serial angioplasty to promote and accelerate AVF maturation. We present a minimally invasive AVF maturation technique utilizing angioplasty, stent-graft, and coil embolization. Methods A 41–year-old white woman presented with an nonmaturing AVF with multiple venous outflow channels. An adequately functioning AVF was achieved after 2 treatments including coil embolization, angioplasty, and stent-graft placement. Results Adequate thrill and dialysis flow was achieved. Patient has done well during short-term follow-up without further intervention. Conclusions BAM techniques can be an effective tool to help a dialysis patient achieve an adequately mature AVF. Additional vascular interventional techniques may be utilized to further improve clinical results. For the purpose of this report we call this technique “augmented balloon-assisted maturation,” or aBAM.
Use of Early Scanning in Fistula Formation for Vascular Access
Authors: Hindle Paul , Ritchie James , Griffiths Gareth , Howd Alison 
Published: November 2010

Purpose To determine the feasibility and role of early scanning in the assessment of arteriovenous fistulae fashioned for vascular access. Methods Retrospective case note analysis of 98 patients who underwent early scanning (between 7 and 28 days) of their fistula as well as routine scanning at 6 weeks over a 2–year period. Results The median time was 16 days to the first scan and 51 days to the second scan. Only 1 fistula was unable to be assessed at the first scan. There were 73 normal first scans, 11 of these had an abnormal second scan showing 4 occlusions, 4 stenoses, and 3 with low flow. There were 25 abnormal first scans. Five were occluded with a mean time to scan of 16.7 days. Eleven of the 25 had a narrow vein. By the second scan, 6 had matured, 3 had occluded, and 2 had failed to mature. Nine of the 25 had low flow, elevated velocities, or a stenosis. By the second scan, 2 had matured, 4 had occluded, and 3 had failed to mature. Conclusions Our results show that early scanning in the surveillance of arteriovenous fistula formation for vascular access is both feasible and reveals a significant number of abnormalities. Early scanning does not remove the need for the routine 6–week scan.
The link between anger and reactive aggression: Insights into anger rumination
Authors: Wen Jie , Wang Guofang , Miao Miao 
Published: May 2024

AbstractThis study examined the mediating role of anger rumination in the relationship between anger and reactive aggression and the potential of adaptive anger rumination in reducing reactive aggression. Study 1, a two‐wave longitudinal survey of 177 Chinese adolescents, showed that anger rumination mediated the relationship between anger and reactive aggression. Study 2, an experimental study with 160 university students, showed that the self‐distanced group had lower aggression than the self‐immersed group, and anger rumination mediated the impact of anger on reactive aggression in only the self‐immersed group. These findings clarify the role of anger rumination concerning the relationship between anger and reactive‐aggression and highlight the importance of self‐distanced anger rumination in preventing reactive aggression among adolescents and young adults.
Ultrafast and Quantitative FRET Sensitization of Singlet Fission in Solution‐Processable Para‐Azaquinodimethane Films
Authors: Alebardi Martina , Munzone Cristina , Sorbelli Enrico , Grasso Alessandro , Mencaroni Letizia , Elisei Fausto , Fortuna Cosimo Gianluca , Spalletti Anna , Bonaccorso Carmela , Carlotti Benedetta 
Published: May 2024

AbstractIn this work, a green protocol for the synthesis of new para‐Azaquinodimethane (pAQM) small molecules, functionalized with anisole (An) or bithiophene (TT) moieties on the central unit and with different alkoxy groups as lateral substituents is developed and reported. The alkoxy lateral substituents are found to strongly impact the solubility and processability of the chromophores. On the other hand, the steady–state and time‐resolved spectroscopic results show completely different spectral and photophysical features for the An‐ and TT‐ derivatives. Only for the TT‐compounds, the nanosecond and femtosecond transient absorption experiments reveal low efficiency of triplet production in solution as well as ultrafast (≈1 ps) and efficient (≈200%) singlet fission (SF) in thin film. The yellow An‐containing molecules are instead used to sensitize the purple SF‐active TT‐compounds via quantitative FRET in mixed thin films, which interestingly exhibit panchromatic absorption extending in the entire visible spectral range. With this study, the synergy between FRET and SF is exploited at the intermolecular level in the solid‐state for the first time by considering unconventional and stable SF chromophores, opening intriguing new possibilities for solar energy harvesting.
Unraveling the Influence of Shell Thickness in Organic Functionalized Cu2O Nanoparticles on C2+ Products Distribution in Electrocatalytic CO2 Reduction
Authors: Hu Jiajun , Osella Silvio , Albero Josep , García Hermenegildo 
Published: May 2024

AbstractCu‐based electrocatalysts exhibit enormous potential for electrochemical CO2 conversion to added‐value products. However, high selectivity, specially toward C2+ products, remains a critical challenge for its implementation in commercial applications. Herein, the study reports the preparation of a series of electrocatalysts based on octadecyl amine (ODA) coated Cu2O nanoparticles (NPs). HRTEM images show ODA coatings with thickness from 1.2 to 4 nm. DFT calculations predict that at low surface coverage, ODA tends to lay on the Cu2O surface, leaving hydrophilic regions. Oppositely, at high surface coverage, the ODA molecules are densely packed, being detrimental for both mass and charge transfer. These changes in ODA molecular arrangement explain differences in product selectivity. In situ Raman spectroscopy has revealed that the optimum ODA thickness contributes to the stabilization of key intermediates in the formation of C2+ products, especially ethanol. Electrochemical impedance spectroscopy and pulse voltammetry measurements confirm that the thicker ODA shells increase charge transfer resistance, while the lowest ODA content promotes faster intermediate desorption rates. At the optimum thickness, the intermediates desorption rates are the slowest, in agreement with the maximum concentration of intermediates observed by in situ Raman spectroscopy, thereby resulting in a Faradaic efficiency to ethanol and ethylene over 73%.
General Modification Strategy on Amorphous Materials to Boost Catalytic Performance
Authors: Jia Binbin , Liu Gui , Zhang Baohong , Zheng Jinlong , Yin Kexin , Lin Jie , Han Chunqiu , Fan Xiaoyu , Xu Mingyuan , Ye Liqun 
Published: May 2024

AbstractAmorphous materials with a high number of unsaturated coordinated dangling bonds exhibits macroscopic homogeneity and isotropy, making it easily modifiable to improve the catalytic properties. At present, several feasible modification strategies for amorphous materials have been proposed and applied to multiple catalytic fields. This review aims to provide a comprehensive overview of recent research advancements in the modification of amorphous materials for catalysis. First, the general strategies for modifying amorphous materials are summarized. Subsequently, the potential applications of modified amorphous materials in electrocatalysis and photocatalysis are highlighted. Additionally, the positive effects of various modification tools on the catalytic properties of amorphous materials are elucidated. Finally, a summary of the challenges and offer a critical perspective on the further development of modified amorphous materials are presented. The primary goal of this review is to offer a systematic understanding of how to enhance catalytic performance and to stimulate further research on amorphous catalysts in the future.
Hydrogen Attenuates Cognitive Impairment in Rat Models of Vascular Dementia by Inhibiting Oxidative Stress and NLRP3 Inflammasome Activation
Authors: Yang Congwen , He Yuxuan , Ren Shuang , Ding Yiqin , Liu Xinru , Li Xue , Sun Hao , Jiao Dezhi , Zhang Haolin , Wang Yingshuai , Sun Lin 
Published: May 2024

AbstractVascular dementia (VaD) is the second most common form of dementia worldwide. Oxidative stress and neuroinflammation are important factors contributing to cognitive dysfunction in patients with VaD. The antioxidant and anti‐inflammatory properties of hydrogen are increasingly being utilized in neurological disorders, but conventional hydrogen delivery has the disadvantage of inefficiency. Therefore, magnesium silicide nanosheets (MSNs) are used to release hydrogen in vivo in larger quantities and for longer periods of time to explore the appropriate dosage and regimen. In this study, it is observed that hydrogen improved learning and working memory in VaD rats in the Morris water maze and Y‐maze, which elicits improved cognitive function. Nissl staining of neurons shows that hydrogen treatment significantly improves edema in neuronal cells. The expression and activation of reactive oxygen species (ROS), Thioredoxin‐interacting protein (TXNIP), NOD‐like receptor protein 3 (NLRP3), caspase‐1, and IL‐1β in the hippocampus are measured via ELISA, Western blotting, real‐time qPCR, and immunofluorescence. The results show that oxidative stress indicators and inflammasome‐related factors are significantly decreased after 7dMSN treatment. Therefore, it is concluded that hydrogen can ameliorate neurological damage and cognitive dysfunction in VaD rats by inhibiting ROS/NLRP3/IL‐1β‐related oxidative stress and inflammation.
Research Progress in Hydrogels for Cartilage Organoids
Authors: Li Xiaolong , Sheng Shihao , Li Guangfeng , Hu Yan , Zhou Fengjin , Geng Zhen , Su Jiacan 
Published: May 2024

AbstractThe repair and regeneration of cartilage has always been a hot topic in medical research. Cartilage organoids (CORGs) are special cartilage tissue created using tissue engineering techniques outside the body. These engineered organoids tissues provide models that simulate the complex biological functions of cartilage, opening new possibilities for cartilage regenerative medicine and treatment strategies. However, it is crucial to establish suitable matrix scaffolds for the cultivation of CORGs. In recent years, utilizing hydrogel to culture stem cells and induce their differentiation into chondrocytes has emerged as a promising method for the in vitro construction of CORGs. In this review, the methods for establishing CORGs are summarized and an overview of the advantages and limitations of using matrigel in the cultivation of such organoids is provided. Furthermore, the importance of cartilage tissue ECM and alternative hydrogel substitutes for Matrigel, such as alginate, peptides, silk fibroin, and DNA derivatives is discussed, and the pros and cons of using these hydrogels for the cultivation of CORGs are outlined. Finally, the challenges and future directions in hydrogel research for CORGs are discussed. It is hoped that this article provides valuable references for the design and development of hydrogels for CORGs.