bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the Factors Influencing User Loyalty, Purchase Intention, and Word-of-Mouth in Virtual Reality
Authors: Jo Hyeon , Jang Sokjong 
Published: April 2024

Abstract
This study investigates the determinants of loyalty, purchase intention, and word-of-mouth (WOM) recommendations in the context of virtual reality (VR) technology, focusing on sensory design components such as visual (color, navigation design, aesthetics, shape, and product design), tactile (touch), and auditory (audio) elements. Employing partial least squares structural equation modeling, data from individuals experienced with VR headsets were analyzed to explore how these sensory aspects influence user behavior. Contrary to expectations, color did not significantly influence attitude or satisfaction. Navigation design significantly impacted both user attitude and satisfaction, highlighting its importance in the VR experience. While aesthetics were found to positively affect user attitude, they did not significantly influence satisfaction. Interestingly, the shape of VR devices influenced satisfaction but not attitude. The product design of VR devices significantly affected both attitude and satisfaction, but audio factors did not significantly impact either. The results indicate that user attitude significantly influences loyalty, purchase intention, and WOM, as does user satisfaction. This reveals the critical role of design and sensory elements in shaping user experiences and preferences within VR environments, offering insights for developers and marketers aiming to enhance user engagement and loyalty.
Text-to-OverpassQL: A Natural Language Interface for Complex Geodata Querying of OpenStreetMap
Authors: Staniek Michael , Schumann Raphael , Züfle Maike , Riezler Stefan 
Published: April 2024

Abstract
We present Text-to-OverpassQL, a task designed to facilitate a natural language interface for querying geodata from OpenStreetMap (OSM). The Overpass Query Language (OverpassQL) allows users to formulate complex database queries and is widely adopted in the OSM ecosystem. Generating Overpass queries from natural language input serves multiple use-cases. It enables novice users to utilize OverpassQL without prior knowledge, assists experienced users with crafting advanced queries, and enables tool-augmented large language models to access information stored in the OSM database. In order to assess the performance of current sequence generation models on this task, we propose OverpassNL,1 a dataset of 8,352 queries with corresponding natural language inputs. We further introduce task specific evaluation metrics and ground the evaluation of the Text-to-OverpassQL task by executing the queries against the OSM database. We establish strong baselines by finetuning sequence-to-sequence models and adapting large language models with in-context examples. The detailed evaluation reveals strengths and weaknesses of the considered learning strategies, laying the foundations for further research into the Text-to-OverpassQL task.
Eliciting the Translation Ability of Large Language Models via Multilingual Finetuning with Translation Instructions
Authors: Li Jiahuan , Zhou Hao , Huang Shujian , Cheng Shanbo , Chen Jiajun 
Published: April 2024

Abstract
Large-scale pretrained language models (LLMs), such as ChatGPT and GPT4, have shown strong abilities in multilingual translation, without being explicitly trained on parallel corpora. It is intriguing how the LLMs obtain their ability to carry out translation instructions for different languages. In this paper, we present a detailed analysis by finetuning a multilingual pretrained language model, XGLM-7.5B, to perform multilingual translation following given instructions. Firstly, we show that multilingual LLMs have stronger translation abilities than previously demonstrated. For a certain language, the translation performance depends on its similarity to English and the amount of data used in the pretraining phase. Secondly, we find that LLMs’ ability to carry out translation instructions relies on the understanding of translation instructions and the alignment among different languages. With multilingual finetuning with translation instructions, LLMs could learn to perform the translation task well even for those language pairs unseen during the instruction tuning phase.
J. T. Fraser and the Temporal Texture of Narrative, an Intersection of Disciplines
Authors: Huisman Rosemary 
Published: April 2024

Abstract
This paper tracks the intersection of three disciplinary areas: J. T. Fraser’s theory of time as nested temporalities, M. A. K. Halliday’s systemic functional linguistics, and English literary history. Narrative theorists claim that narrative is a use of language that organizes the human understanding of time. However, narrative is not limited to only one temporality but can include the multiple temporalities that appear in Fraser’s model. This approach repudiates studies of narrative, such as those in the structuralist tradition of dual discourse and story, which assume “time” has a singular meaning equivalent to Fraser’s “biotemporality.” Each temporality can be associated with a different type of coherent story, and thus the one narrative can weave together stories with different temporalities, its “temporal texture.” Fraser and Halliday both recognize Gerald Edelman’s dual model of the brain and the emergence of language through the evolution of the human brain from “primary consciousness” to “higher-order consciousness.” Language evolves in the “human umwelt” of everyday experience of material, mental and social worlds in the gravitational context of this earth. Thus pre-twentieth century narratives, with various textures, tell stories of Fraser’s temporalities of human earthly experience. Fraser’s model also describes the “unearthly temporalities” that, from the twentieth century, modern science and technology have added to human understanding, producing what he calls the “extended human umwelt.” The twentieth century narratives of modernism and postmodernism may include these temporalities in their texture. However, the digital culture of the twenty-first century already reshapes the human umwelt; the paper ends with some speculation on changes in organization of temporal meaning in the evolving context.
A combination of laparoscopy and bilateral uterine artery occlusion for the treatment of type II cesarean scar pregnancy: a retrospective analysis
Authors: Wang Hongyan , Xue Fangfang , Wang Wenying 
Published: April 2024

Objective We investigated the efficacy of a combination of laparoscopy and bilateral uterine artery occlusion (BUAO) for the treatment of type II cesarean scar pregnancy (CSP). Methods Patients with type II CSP underwent laparoscopy + bilateral uterine artery embolization (control group) or laparoscopy + BUAO (study group). Data regarding the duration of surgery, intraoperative hemorrhage, postoperative complications, the duration of the hospital stay, and the costs of hospitalization were retrospectively collected. One year later, the time to the return of the β-human chorionic gonadotropin (β-hCG) concentration to normal and to the return of menstruation were compared. Results The duration of surgery, time to the return of menstruation, and incidence of postoperative complications in the study group were significantly less than in the control group, but there was no significant difference in the time for β-hCG to return to normal or the volume of intraoperative hemorrhage. The duration of hospitalization and costs for the control group were higher than those for the study group. Conclusion Laparoscopy in combination with BUAO is associated with minimal trauma, rapid recovery, a short duration of surgery, low cost of hospitalization, and a low postoperative complication rate. Thus, it represents a useful new surgical treatment for type II CSP.
Exploring the efficacy of catha edulis extract-loaded nanofibrous scaffolds seeded with bone marrow-derived stem cells for diabetic wound healing: A preclinical investigation
Authors: Song Yinsen , Zhang Sisen , Fan Tianli , Yang Zhenzhen , Li Peiliang , Zhang Lu , Gao Na , Mei Wei 
Published: April 2024

Objectives: The aim of this study was to investigate the potential of incorporating catha edulis extract into polycaprolacton/gelatin scaffolds using electrospinning technique for the treatment of diabetic wounds in a rat model. Methods: The in vitro characterization of the scaffolds was performed using various assays, including anti-inflammatory assay, microstructure study, DPPH radical scavenging assay, cell viability assay, hemocompatibility assay, and bacterial penetration assays. The scaffolds were then seeded with bone marrow-derived stem cells and cultured before implantation into the rat model. Results: The results of the in vitro study showed that the produced scaffolds were nanofibrous, antioxidative, and non-toxic to skin cells. In vivo study demonstrated that the stem cell and catha edulis extract-loaded scaffolds had the highest rate of wound closure and histomorphometric parameters compared to other groups. Moreover, gene expression studies showed that the developed wound dressings increased the expression of VEGF gene and reduced the expression of glutathione peroxidase gene. Conclusion: These findings suggest that the catha edulis extract-loaded polycaprolacton/gelatin scaffolds could be a promising therapeutic option for diabetic wounds.
Addition of constitutional symptoms to the SLEDAI-2K improves overall disease activity assessment: A pilot study
Authors: Anderson Erik W , Sansone Marissa , Shah Bhakti , Kline Myriam , Franchin Giovanni , Aranow Cynthia , Mackay Meggan 
Published: April 2024

Objective Constitutional symptoms (fatigue, lymphadenopathy, and weight loss) are not included in the SLE disease activity index-2000 (SLEDAI-2K). In this pilot study, we assessed the concurrent and construct validity of a revised SLEDAI-2K (SLED-R) that included these symptoms with the original SLEDAI-2K (SLED-O), using the physician global assessment of disease activity (PGA) as the reference. Methods Our revised SLED-R substituted the SLED-O’s fever descriptor with a constitutional descriptor that included fever, fatigue, lymphadenopathy, and/or weight loss. SLED-O, SLED-R, PGA and patient global assessment (PtGA) scores were collected prospectively. Bland-Altman correlations for repeated measures were calculated and Meng’s z-test was used to compare correlations between dependent and overlapping correlation coefficients. Associations between constitutional symptoms and disease activity measures were analyzed using Mann-Whitney U, Kruskal-Wallis, Chi-square tests and repeated measures correlations. Results 1123 SLED-O, SLED-R, PGA, and 1066 PtGA were collected in 239 subjects. The new descriptor was scored in 45 subjects (18.8%) and 92 instances (8.1%), while the original descriptor, fever, was scored in only 4 subjects (1.7%) and 5 instances (0.4%). Mean SLED-O, PGA and PtGA scores were higher when the constitutional descriptor was scored versus not ( p < .001). The correlation between SLED-R and PGA was marginally higher than between SLED-O and PGA ( p < .001). Fatigue contributed most to this increase ( p = .001) and associated with both higher PGA and PtGA scores ( p < .001). Mean SLED-O and PGA scores were higher when ≥1 constitutional symptom(s) were scored versus not ( p < .002). Correlations between PGA and PtGA when the new descriptor was scored versus not were similar ( p = .860). The frequency of concordance between PGA and PtGA was lower when the new descriptor was scored (55%) versus not (72.5%), with PGA > PtGA when the new descriptor was scored ( p < .001). Conclusion The addition of constitutional symptoms to SLEDAI-2K, particularly fatigue, resulted in a marginal increase in its correlation with PGA, and new constitutional symptoms associated with higher SLED-O and PGA scores. As fatigue is subjective and difficult to attribute to SLE, its validity and inter-rater reliability in scoring remains uncertain. The clinical utility of SLED-R remains unclear, and further studies of its validity and reliability are needed.
Factors associated with healthcare transition readiness for adolescents with chronic conditions: A cross-sectional study
Authors: Hong Hye Seung , Im YeoJin 
Published: April 2024

Healthcare transition readiness (HCTR) plays a vital role by fostering autonomy, self-management skills, and active involvement in healthcare, leading to positive health outcomes. This study aimed to examine the factors associated with HCTR in adolescents with chronic conditions (ACCs) including adolescents’ autonomy, parental overprotection, and autonomy support from healthcare providers (HCPs). This descriptive study included 107 adolescents aged 14–19 years (median age: 17 years, IQR = 1), recruited from online communities and support groups in South Korea. Data were analyzed using hierarchical linear regression. Our research has shown that HCTR is linked to a lower level of parental overprotection (β = −0.46, 95% CI [−0.59, −0.33]) and higher levels of autonomy support from HCPs (β = 0.46, 95% CI [0.36, 0.56]). Among general characteristics, we also found that having a transfer plan to adult care (β = 0.24, 95% CI [0.04, 0.44]) is significantly associated with HCTR. This study contributes to a broader understanding of HCTR by examining its associated factors in ACC. The results emphasize the pivotal roles of parental involvement, healthcare provider support, and structured transition to adult care in enhancing HCTR. These findings underscore the need for comprehensive assistance to ensure successful healthcare transitions.
Associations between food intake and psychosomatic symptoms in 16-year-old adolescents
Authors: Tell Maria Norburg , Hedin Katarina , Nilsson Mats , Golsäter Marie , Lingfors Hans 
Published: April 2024

Aims: An increase in psychosomatic symptoms among adolescents has recently been reported. Few studies have examined the relation between food intake and psychosomatic symptoms. The aim was to study the association between food intake and overall psychosomatic burden and separate psychosomatic symptoms. Methods: In this cross-sectional study, we used data from 6248 girls and 7153 boys in south-east Sweden who turned 16 years of age during the academic years 2009/2010 to 2015/2016 and responded to a health questionnaire at the school health services. The association between overall healthy food intake and a low psychosomatic burden was calculated as odds ratios (95% confidence interval) and stratified for other lifestyle habits and gender. Results: Sixty-nine per cent of the boys and 35% of the girls had a low psychosomatic burden. There was a positive association between an overall healthy food intake and a low psychosomatic burden ( P<0.0001), regardless of other lifestyle habits and gender. An overall healthy food intake was also positively associated with a lower frequency of the separate psychosomatic symptoms of concentration difficulties, sleep difficulties, a poor appetite or dizziness ( P<0.0001). Conclusions: A healthy food intake seems to be associated with a low psychosomatic burden among adolescents. Further knowledge is needed to explore whether an improved food intake can reduce psychosomatic symptoms and enhance mental health.
Emotional experiences in palliative care and professional quality of life: a qualitative approach
Authors: Cañas-Lerma Ana Josefa , Hidalgo-Andrade Paula , Araujo-Lugo Viviana , Moya Gabriela , Verger Sebastià 
Published: April 2024

Objective: To explore the experiences that significantly impact the professional quality of life of people providing palliative care (PC) in Ecuador. Design: Observational cross-sectional qualitative research. Methods: In September 2022, 10 focus groups were carried out in four cities in Ecuador; each group lasted from 1 to 2 h, was audio recorded, and transcribed verbatim. Recruitment was conducted through convenience sampling, and a total of 71 individuals (15 students, 50 professionals, and 6 volunteers) linked to PC participated. Content analysis with a phenomenological and inductive approach was used to analyze the data. Results: People recognized their experiences in PC as having positive and negative impacts on their professional quality of life. Experiences were mapped as affecting them at individual, relational, and contextual levels. These experiences included personal growth, opportunity to provide care, teamwork, death-related issues, inability to deal with work-related stress, social acceptance of PC, and dealing with inefficient health systems, among others. Conclusion: Despite the positive emotions that arise with caring for others, individuals working and volunteering in PC experience situations that influence their professional quality of life. Addressing these factors to increase satisfaction and ease the burden of PC work is essential. Undergraduate education, continuous professional training, and PC teams should incorporate actions to address these factors at all levels, such as teaching coping skills, fostering social support, and increasing awareness of PC.
Venous thromboembolism characteristics and outcomes among RIETE patients tested and untested for inherited thrombophilia
Authors: Cohen Omri , Waldman Radinsky Liat , Kenet Gili , Mahé Isabelle , Barillari Giovanni , Soler Silvia , Sigüenza Patricia , Del Valle Morales María , Villares Paula , Monreal Manuel 
Published: April 2024

Abstract
Inherited thrombophilia (IT) workup is commonly pursued in patients with venous thromboembolism (VTE). Recent American Society of Hematology guidelines recommend a selective approach to IT testing, nevertheless, evidence on whether thrombophilia testing can actually improve patient-important outcomes through tailored management is limited. Data from the large, prospective Registro Informatizado de Enfermedad TromboEmbólica (RIETE) registry were analyzed to compare VTE risk factors, management, and outcomes between patients who were tested for IT and untested patients, during anticoagulant treatment and after its discontinuation. Among 103 818 patients enrolled in RIETE, 21 089 (20.3%) were tested for IT, 8422 (8.1%) tested positive, and 82 729 (79.7%) were not tested. IT testing was more frequent in patients with VTE provoked by minor risk factors and less common in those with major risk factors such as surgery or active cancer. Choices of anticoagulant treatment did not differ based on IT testing results. Untested patients exhibited inferior outcomes across all VTE categories, with higher rates of VTE recurrence, major bleeding, mortality, and notably, cancer-related mortality. After treatment discontinuation, IT-negative patients with surgically provoked VTE showed lower recurrence rates. For immobilization-related VTE as well as in estrogen-related VTE, no significant differences in recurrence rates were observed between IT-negative and IT-positive patients. However, IT-negative patients with pregnancy or postpartum-related VTE had significantly lower recurrence rates. Patients with unprovoked VTE, particularly those testing positive for IT, had high recurrence rates after treatment. These findings underscore the complex role of IT testing in managing VTE, supporting personalized treatment strategies that consider VTE risk factors and comorbidities. The trial was registered at www.clinicaltrials.gov as #NCT02832245.
DISPLACE study shows poor quality of transcranial doppler ultrasound for stroke risk screening in sickle cell anemia
Authors: Davidow Kimberly A. , Miller Robin E. , Phillips Shannon M. , Schlenz Alyssa M. , Mueller Martina , Hulbert Monica L. , Hsu Lewis L. , Bhasin Neha , Adams Robert J. , Kanter Julie 
Published: April 2024

Abstract
Children with sickle cell anemia (SCA) are at increased risk of stroke when compared with their age-based counterparts. The Stroke Prevention Trial in Sickle Cell Anemia (STOP) previously demonstrated that with the use of transcranial Doppler ultrasound (TCD; Sickle Stroke Screen) and chronic red cell transfusion, the risk of stroke is reduced by over 90%. The STOP criteria detailed the type and method of measurement required; the time–averaged mean maximum velocity (TAMMV). Unfortunately, it has been difficult to adhere to the appropriate TAMMV measurements. The objectives of this study were to assess the quality of TCD and transcranial Doppler imaging (TCDi) reports to determine the report quality and accuracy. This is a subanalysis of the DISPLACE (Dissemination and Implementation of Stroke Prevention Looking at the Care Environment) study. Over 12 000 TCD/TCDi reports were collected during this study from 28 institutions; 391 TCDs were reviewed for this subanalysis. There were significant variations in the vessels being assessed, the velocities used to define abnormal results, and who was interpreting the scans. In 52% of reports, it was impossible to identify whether the TAMMV was what was measured. Similarly, it was only clear in 42% of reports that the TAMMV was used to interpret the examination as normal/abnormal. Given this inconsistency, we strongly recommend standardization of TCD/TCDi reporting, specialized training for those performing and interpreting the scans in the use of TCD/TCDi in patients with SCA, internal quality assurance, and institutional quality improvement work to ensure appropriate use of this potentially lifesaving technology.
Defining primary refractory large B-cell lymphoma
Authors: Bock Allison M. , Mwangi Raphael , Wang Yucai , Khurana Arushi , Maurer Matthew J. , Ayers Amy , Kahl Brad S. , Martin Peter , Cohen Jonathon B. , Casulo Carla , Lossos Izidore S. , Farooq Umar , Ayyappan Sabarish , Reicks Tanner , Habermann Thomas M. , Witzig Thomas E. , Flowers Christopher R. , Cerhan James R. , Nastoupil Loretta J. , Nowakowski Grzegorz S. 
Published: April 2024

Abstract
Patients with large B-cell lymphoma (LBCL) that fail to achieve a complete response (CR) or who relapse early after anthracycline-containing immunochemotherapy (IC) have a poor prognosis and are commonly considered to have “primary refractory disease.” However, different definitions of primary refractory disease are used in the literature and clinical practice. In this study, we examined variation in the time to relapse used to define refractory status and association with survival outcomes in patients with primary refractory LBCL in a single-center prospective cohort with validation in an independent multicenter cohort. Patients with newly diagnosed LBCL were enrolled in the Molecular Epidemiological Resource cohort (MER; N = 949) or the Lymphoma Epidemiology of Outcomes cohort (LEO; N = 2755) from September 2002 to May 2021. Primary refractory LBCL was defined as no response (stable disease [SD]) or progressive disease (PD) during, or by the end of, frontline (1L) IC (primary PD; PPD); partial response at end of treatment (EOT PR); or relapse within 3 to 12 months after achieving CR at EOT to 1L IC (early relapse). In the MER cohort, patients with PPD had inferior overall survival (OS; 2-year OS rate: 15% MER, 31% LEO) when compared with other subgroups considered in defining primary refractory disease, EOT PR (2-year OS rate: 38% MER, 50% LEO) and early relapse (2-year OS rate: 44% MER, 58% LEO). Among patients receiving 1L IC with curative intent, we identified that patients with PPD are the key subgroup with poor outcomes. We propose a definition of primary refractory LBCL as SD or PD during, or by the end of, 1L treatment.