bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indicators of endocrine function of muscle and fat tissue in athletes participating in martial arts
Authors: Shestopalov A. V. , Davydov V. V. , Merkel K. P. , Grigoryeva T. V. , Martykanova D. S. , Davletova N. Сh. , Laikov A. V. , Roumiantsev S. A. 
Published: May 2024

Purpose of the study: the aim of that study was an investigation of the level of adipokines, myokines and growth factors in the blood of athletes involved in acyclic sports — martial arts.Materials and methods: we have investigated 15 male athletes aged 15–19 years. The control group included 15 healthy men of the same age who did not engage in sports. In the blood serum of the all subjects, leptin, adiponectin, resistin, apelin, irisin, adipsin, myostatin, FGF21, osteocrin and oncostatin were determined using a multiplex analysis.Results: studies have shown that long-term regular martial arts training is accompanied by a decrease in the level of leptin, resistin and oncostatin M in the blood of athletes and a change in correlations between the content of the studied myokines, adipokines and growth factors compared with their values in the control group.Conclusions: regular long-term martial arts training is accompanied by a decrease in the level of leptin, resistin and oncostatin M in the blood of athletes. Their occurrence is associated with changes in the state of regulatory systems that control the production and secretion of myokines, adipokines and growth factors in adipose, muscle, nervous and bone tissue. The resulting shifts ensure adaptation of the athletes’ bodies to physical activity.
Ativistas Ambientais: Relato de uma Prática Pedagógica
Authors: Felipe Rosane Terezinha , Filho Evandro Alves Barbosa 
Published: May 2024

RESUMO
O presente artigo tem como objetivo apresentar uma prática pedagógica realizada com estudantes do Novo Ensino Médio, turmas de 1º e 2º série. A atividade consistia na pesquisa, elaboração de um material e a apresentação para a turma dos resultados alcançados, possuindo como objeto de estudos ativistas, líderes ou pessoas que inspiram em diferentes áreas do saber. Para este trabalho, destacam-se nomes que contribuíram e que contribuem com as questões ambientais, alguns jovens e outros com uma trajetória de ativismo, alguns reconhecidos localmente, nacionalmente e mundialmente. Suas contribuições são através de manifestações, mobilizações, representações ou realizando ações práticas. A metodologia utilizada foi a de oficina participativa, que consistia na explicação dos conceitos e da proposta da atividade e diálogos sobre ela, pesquisa da vida, obra e contribuições da/do ativista de referência e apresentação do trabalho final. O resultado esperado é que os estudantes tenham a oportunidade de conhecer diferentes referências, ativistas, despertar nos mesmos reflexões acerca dos hábitos e da importância da participação e do ativismo político ambiental.

Palavras-chave: Pesquisa; Ativistas Ambientais; Contribuições; Reflexões
Digitalization of the economy of Kazakhstan and development of accounting
Authors: Сыдыкова А.Н. 
Published: May 2024

Разработка национальных программ, направленных на развитие экономики нового поколения, включая разработку и внедрение технологий, анализ «больших данных» и внедрение новых методов управления не только с точки зрения социально-экономической благосостояния государств, но и программ цифрового развития глобализации и других участников мирового рынка.Это стратегически важная задача как условие сохранения суверенитета в рамках ее реализации. До этого в Казахстане была запущена международная образовательная программа «Болашак» и сформировано «электронное правительство». Это способствовало переходу к информационному обществу, совершенствованию государственного управления, созданию институтов «открытого и мобильного правительства», повышению доступности информационной инфраструктуры не только для корпоративных структур, но и для граждан страны.
Жаңа ұрпақ экономикасын дамытуға, соның ішінде технологияларды әзірлеуге және енгізуге, «үлкен деректерді» сараптауға және басқарудың жаңа әдістерін енгізуге бағытталған ұлттық бағдарламаларды әзірлеу мемлекеттердің әлеуметтік-экономикалық әл-ауқаты тұрғысынан ғана емес, сондай-ақ жаһандандыру және әлемдік нарықтың басқа да қатысушыларының цифрлық даму бағдарламаларын іске асыру аясында егемендікті сақтау шарты ретінде де стратегиялық маңызды міндеті болып отыр. Бұған дейін Қазақстанда «Болашақ» халықаралық білім беру бағдарламасы басталды және «электрондық үкімет» қалыптасты. Бұл ақпараттық қоғамға өтуге, мемлекеттік басқаруды жетілдіруге, «ашық және мобильді үкіметтің» институттарын құруға, ақпараттық инфрақұрылымның корпоративтік құрылымдарға ғана емес, елдің азаматтарына да қол жетімділігін арттыруға ықпал етті.
New generation to develop economic data freezing, development of technologies and introduction of new methods of "Great data", "Great data" and the introduction of newly social for the preservation of sovereignty retinde de strategilik manyezdy mındetı bolí p otór. Bank of Kazakhstan "Bolashak" international education program was launched and "electronic government" was created. This is the institutional framework of the "open and mobile government", information infrastructure corporation for the transition to the information system, improvement of public administration. If you have pressed the button, please select an item
Using the Theory of Affordances to Understand Environment–Play Transactions: Environmental Taxonomy of Outdoor Play Space Features—A Scoping Review
Authors: Morgenthaler Thomas , Lynch Helen , Loebach Janet , Pentland Duncan , Schulze Christina 
Published: May 2024

Abstract
Importance: The transactions between the physical environment and children’s play have not been well studied. The theory of affordances provides a way to better understand how environmental characteristics offer opportunities for play occupation.
Objective: To investigate the relationship between environmental characteristics of outdoor play spaces and children’s outdoor play and to develop an environmental taxonomy to support the analysis of play affordances in community play spaces.
Data Sources: Peer-reviewed literature (1974–2023) was sourced from a previously published scoping review (Morgenthaler, Schulze, et al., 2023). The Academic Search Complete, Avery Index to Architectural Periodicals, CINAHL, MEDLINE, PsycINFO, Scopus, and Web of Science databases were searched using the keywords and synonyms of playground, environmental qualities, and children with and without disabilities.
Study Selection and Data Collection: A secondary analysis of the previously published scoping review was conducted. Included studies were those that provided descriptions of physical environment–play activity transactions.
Findings: A qualitative content analysis of 45 articles was conducted and used to form an environmental taxonomy. This taxonomy consisted of 14 space and object categories defined by their functional qualities and linked to play affordances. An array of 284 play occupations were identified in different forms. Play affordances of spaces and object categories and their functional environmental qualities were subsequently identified.
Conclusions and Relevance: This study provides evidence to support the understanding of how the physical environment shapes children’s outdoor play occupations.
Plain-Language Summary: The study authors developed the Environmental Taxonomy of Outdoor Play Space Features as a tool that occupational therapists can use to better understand and describe how the physical environment shapes opportunities for play. The tool could also be useful to justify environmental intervention in schools and public playgrounds to create spaces that support more play for a diversity of children.
Dämonisch, das Dämonische (Daemonic, the Daemonic)
Authors: Nicholls Angus 
Published: May 2024

Due to their prominence in Goethe’s autobiography (Dichtung und Wahrheit, Poetry and Truth) and in Johann Peter Eckermann’s Gespräche mit Goethe (Conversations with Goethe), Goethe scholarship has associated the lexemes dämonisch and das Dämonische with Goethe’s life, and especially with his seemingly divinely inspired artistic productivity. Yet when these lexemes are considered in relation to the ancient Greek term from which they are derived – δαíμων (German: Dämon; English: daimon or daemon) – they appear as part of a larger tradition in European thought that is concerned with non-rational sources of inspiration, as well as with the limits of reason itself. Far from offering a consistent theory or concept of the daemonic, Goethe uses this term and its cognates in various ways: to refer to a mysterious and terrifying force that influences one’s life and seems to operate at the nexus between character and fate; as a poetic topos that depicts the relation between the striving subject and its external world; as the morphological core of the personality associated with the tradition of astrology, a core which is seen as the locus of one’s productivity; and as a name or placeholder for phenomena that escape our rational comprehension. Precisely due to the flexibility and ambiguity of these terms, Goethe’s use of them has enjoyed a rich reception in fields as various as theology, religious studies, and philosophy from the nineteenth century until the present.
A survey of Phlebotomine sand flies across their northern distribution range limit in Western Europe
Authors: Risueño J. , Bersihand S. , Bender C. , Cornen T. , De Boer K. , Ibáñez-Justicia A. , Rey D. , Rozier Y. , Schneider A. , Stroo A. , Vanslembrouck A. , Van Bortel W. , Weigand A. , Zambianchi D. , Pérez Cutillas P. , Oerther S. , Braks M. , Wint G.R.W. , Berriatua E. , Schaffner F. 
Published: May 2024

Abstract
Sand flies are vectors of Leishmania spp. protozoa, phleboviruses and Bartonella bacilliformis. In this study we surveyed areas of central-western Europe, encompassing the northern limit of the known sand fly distribution, and investigated the relationship between their presence and environmental variables. In this area, very limited occurrence data exists, none of them recent. Sampling was performed in July and August 2023 using CDC-light traps, sticky traps and human landing captures, at 179 selected sites in 48 municipalities. A total of 55 sand fly specimens were collected at 11% (20/179) of the sites sampled – including 16 sites in France, 2 in Luxembourg and 1 in Germany – comprising the first published records for Luxembourg and the Trier-Saarburg County of Germany. No sand flies were detected in Belgium or in the Netherlands. Two species were captured: Phlebotomus mascittii (37 females, 2 males) and Ph. perniciosus (1 female, 15 males). The latter species was only found in Savoie, the southernmost region sampled in France, while the former species was detected as far north as latitude 50°N. Logistic regression modelling indicated that the probability of sand fly presence gradually decreased with increasing latitude and altitude (P < 0.05), and it was not associated to other analysed landscape features in the proximity of the traps. The study confirms and provides new evidence for the presence of sand flies in areas of Western Europe and highlights the need to be aware of potential autochthonous transmission of sand fly-borne pathogens in these areas.
Oscillatory Properties of Second Order Half-Linear Delay Difference Equations
Authors: K. Masaniammal  
Published: May 2024

This study explores, some necessary and sufficient conditions that are established for oscillatory properties of second order half-linear delay difference equations of the form Δ(p(ξ)(Δx(ξ))^r )+q(ξ)x^s (σ(ξ))=0, for ξ≥ξ_0 . Under the assumption ∑_(t=ξ_0)^(ξ-1) 1/(p^(1/r) (t))=∞. Two cases are considered for r<s and r>s, where r and s are the quotients of two positive odd integers. The effectiveness and applicability of the result are illustrated through few examples.
Event Free Survival and Overall Survival in Adolescents with Acute Lymphoblastic Leukemia: A Retrospective Review
Authors: Malaeb Farah , Muakkit Samar 
Published: May 2024

Aim The therapeutic progress achieved with pediatric regimens in childhood acute lymphoblastic leukemia (ALL) has contributed to the increase of their use in adolescents and young adults (AYA) worldwide, in an attempt to achieve a better event free survival and overall survival in AYA’s with ALL. The outcome of AYA’s with ALL has not been published in Lebanon, neither has the therapy related complications, morbidity and mortality rate. Hence, we decided to conduct a retrospective chart review to include all adolescents aged 12-18 years old, diagnosed with ALL, treated at Children’s Cancer Center of Lebanon, based on the “CCCL/ALL I Study for newly diagnosed patients with Acute Lymphoblastic Leukemia”, enrolled since October 2011 until March 2019. Materials and Methods A retrospective chart review was carried on all adolescents aged 12-18 years old, diagnosed with ALL, treated at Children’s Cancer Center of Lebanon, based on the “CCCL/ALL I Study for newly diagnosed patients with Acute Lymphoblastic Leukemia”, enrolled since October 2011 until March 2019. Data collected included patient’s characteristics (age, gender), leukemia characteristics, MRD at different times, complications during treatment and up to 3 years after ending treatment, in addition to mortality, if present and its causes. Results A total of 38 charts were reviewed, of which 66% of those were males, 79% had B lineage ALL, 13% had T-lineage ALL and 8% had biphenotypic leukemia; none of the patients had CNS disease upon presentation, 3% had testicular involvement upfront. 68% of the patients were stratified as intermediate risk patients, 19% as low risk and 13% as high-risk patients according to the St. Jude consortium classification. With a median follow-up of 5 years, the overall survival was 86%, the relapse rate was 10%. The incidence of pancreatitis and thromboembolic complications was 36% and 30%, respectively. The rate of AVN reached 42% in our patients. Conclusion Adolescents diagnosed with acute lymphoblastic leukemia, in Lebanon, between October 2011 and March 2019, treated as per the CCCL/ALL I Study for newly diagnosed patients with Acute Lymphoblastic Leukemia, based on the SJCRH total XV protocol, showed a similar survival rate in comparison to similarly aged patients treated with other pediatric ALL protocols, worldwide. The complication rate was similar as well, though our patients tended to have a higher incidence of AVN, up to 42%, almost doubling the incidence of AVN in published outcomes of similarly aged patients.
Aprendizagem baseada em problemas: avaliação e saúde mental do estudante de medicina
Authors: Assolini Filomena Elaine Paiva , Bandos Rogério Dutra 
Published: May 2024

Este artigo traz um pequeno recorte de uma tese de doutorado, em fase de conclusão. Ao longo de nossa investigação, identificamos a relação entre a avaliação formativa presente em algumas tutorias da Aprendizagem Baseada em Problemas (ABP ou PBL – Problem-Based Learning) ABP, e queixas e sintomas de estudantes de Medicina, notadamente, ansiedade e estresse. À luz da Análise de Discurso de Matriz Francesa (AD), campo teórico-metodológico ao qual nos filiamos, foram entrevistados dezesseis estudantes de dois cursos de Medicina do estado de São Paulo, Brasil. A partir de um corpus constituído por recortes das entrevistas, selecionamos algumas sequências discursivas para análise. Perscrutamos indícios línguístico-discursivos na materialidade linguística, que nos levaram a gestos interpretativos e análises discursivas. Os resultados de nossas análises assinalam que: 1º) um dos motivos do descontentamento estudantil, responsável por gerar ansiedade e estresse, é a metodologia aplicada na avaliação formativa. Tal metodologia ainda é atravessada por marcas do discurso pedagógico tradicional; 2º) avaliação tradicional, que não oferece espaços de fala e formulação de pensamentos autorais para os estudantes, gera descontentamento, tristeza e desilusão com a ABP e com o próprio curso. Quando desenvolvida de modo a oferecer oportunidades para que os alunos não sejam interditados em seus argumentos e propostas, a ABP é uma alternativa metodológica ativa de ensino que proporciona um aprendizado diferenciado, pois, além de conduzir os educandos a pensarem e refletirem criticamente sobre os mais variados tipos de problemas, casos e situações da área médica, contribui para uma formação acadêmica e pessoal marcadas pela ética, respeito à vida, ao próximo e à sua história e palavra.
Determinantes do emprego de doentes crônicos: penalidades múltiplas de gênero e condição econômica no Brasil
Authors: Souza Solange de Cassia Inforzato de , Gomes Magno Rogério , Henrique Franciele , Ricardo Milena Capitó 
Published: May 2024

O objetivo deste artigo é investigar os impactos das doenças crônicas não transmissíveis sobre o emprego de indivíduos, segundo o gênero e a condição econômica no Brasil. A partir dos microdados da PNS 2019, aplica-se a Extended probit regression, cujos resultados mostram que o sexo feminino e a condição econômica fragilizada são os dois elementos que mais impactam negativamente as chances de ocupação de indivíduos doentes. Idade, posições de responsabilidade na família e a escolaridade mais elevada aliviam esses efeitos no mercado brasileiro para os doentes crônicos. As consubstancialidades de gênero, doença e pobreza prejudicam o envolvimento ocupacional das mulheres, e ainda se intensificam com a baixa instrução. Reflexões e ações baseadas nessas evidências podem mitigar os descompassos de gênero e de situação econômica dos indivíduos doentes no país.
Autonomic Dysfunction in Amyotrophic Lateral Sclerosis – A Case-Control Study
Authors: Hasan Mehedi , Alam SK Mahbub , Rahman Hasan Zahidur , Khan Md. Abdullah Saeed , Huq Muhammad Rezeul 
Published: May 2024

Introduction. This study aimed to explore autonomic nervous system involvement in amyotrophic lateral sclerosis (ALS) pa- tients by evaluating sympathetic skin response (SSR).
Materials and Methods. The study included 35 sporadic (ALS) patients (cases), and 35 healthy age and sex-matched participants (controls) aged <60 years. SSR was recorded in the electrophysiology lab of the Neurology Department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Patients with diseases associated with peripheral or autonomic neuropathy were excluded. Prolonged latency (delayed SSR) or an ab- sent response was considered abnormal SSR.
Results. SSR was found to be abnormal in 17 (48.6 %) ALS cases, with an absent response in the upper limbs of six cases (17.1%). Abnormal SSR was more prevalent in the lower limbs, with 33 (94.3%) and 20 (57.1%) cases having a delayed or absent response, respectively. In comparison, SSR was normal in all control participants (P-value <0.05). Abnormal SSR was significantly more common in the lower limbs of ALS cases with bulbar palsy than those without bulbar palsy (P-value=0.04). There was no association of SSR with disease severity and duration.
Conclusion. ALS is significantly associated with abnormal SSR, indicating autonomic nervous system involvement. There could also be an associa- tion between bulbar palsy and abnormal SSR among ALS patients. Further studies should be carried out to determine the as- sociation of abnormal SSR with disease severity, duration, and type.
School Heads’ Accountability in School Management
Authors: Rose G. Pagunsan Cherry , Moyani Jr. Gregorio 
Published: May 2024

School heads are considered persons in authority who manage the school and are considered the pillars of the educational system. Along with their authority, they are accountable for the outcomes of the school operations, programs, and projects. In this context, this paper determined the school heads’ levels of accountability in school management in a District, in a first-class municipality, in Negros Occidental during the School Year 2022-2023. Data needed for this descriptive study was collected from 133 respondents, mostly senior educators with bachelor's degrees, using a self-made survey questionnaire that passed the rigorous test of validity and reliability. The ensuing analysis showed school heads possessing a very high level of accountability in the domain of focusing on teaching and learning. However, in the domain of leading strategically, managing school operations and resources, developing self and others, and building connections, the level of accountability was observed to be high. The perception of school heads' accountability varied based on profile variables such as age, length of service, and highest educational attainment. Younger teachers and those with shorter length of service perceived higher levels of accountability. Moreover, teachers with lower educational attainment attributed higher levels of accountability across all domains. The findings of this study call for the school heads’ and those aspiring to become school heads to the importance of practicing accountability as leaders of the school, for more efficient and effective school leaders and eventually improve the level of school-based management.
Analisis Hukum Terhadap Putusan Kasasi Mahkamah Agung Nomor 1146 K/PDT.SUS-HKI.2020 Terkait Penerapan Persamaan pada Pokoknya dalam Kasus Merek “PREDATOR” Berdasarkan Undang-Undang Nomor 20 Tahun 2016 Tentang Merek dan Indikasi Geografis
Authors: Christina Marintan Gabriella , Ratna Permata Rika , Sudaryat Sudaryat 
Published: May 2024

Keberadaan merek saat ini memilik peran penting sebagai suatu identitas yang baik untuk melindungi produk serta menjadi jaminan atas kualitas produk atau layanan dalam persaingan pasar. Untuk dapat dilindungi, suatu merek harus didaftarkan terlebih dahulu dan sudah memenuhi syarat yang telah ditentukan oleh undang-undang. Merek dapat saja ditolak atau dibatalkan apabila tidak memenuhi syarat yang ditentukan. Pada kasus sengketa merek “PREDATOR”, Acer Incorporated selaku Penggugat mengajukan gugatan kepada Komisi Banding Merek yang telah mengajukan putusan untuk menolak permohonan banding atas pendaftaran merek “PREDATOR” milik Penggugat karena adanya persamaan pada pokoknya dengan merek yang telah terdaftar dengan nama dan jenis barang yang sama. Penelitian ini menggunakan metode penelitian dengan penedekatan yuridis normatif berdasarkan hukum yang berlaku. Hasil penelitian menunjukan bahwa Pertama, terdapat disparitas antara Majelis Hakim pada Pengadilan Niaga dan Hakim Agung pada Pengadilan Kasasi. Kedua, terdapat inkosistensi pada Putusan Majelis Kasasi dalam menafsirkan unsur Persamaan Pada Pokoknya dan menafsirkan tujuan dari gugatan Penggugat