bluuebunny/crossref_metadata_2025_split huggingface dataset:
X‐ray Diffraction Analysis of New ring‐Enlargement Derivatives of Penicillin G: 2‐thia‐3,3‐Dimethyl‐4R‐(t‐Butyloxycarbonylmethylene) Carboxylate‐5,7‐Diaza‐6‐Oxo‐8r‐Phenylacetamido‐Bicyclo‐1r‐[3,3,0]Octane and 2‐Thia‐3,3‐Dimethyl‐4R‐(t‐Butyloxycarbonylmethylene) Carboxylate‐5,7‐Diaza‐6‐oxo‐7‐Benzoyl‐8R‐Phenylacetamido‐Bicyclo‐1 R‐[3,3,0]octane
Authors: Declercq J. P. , van Meerssche M. , Marchand‐Brynaert J. 
Published: September 2010

AbstractThe X‐ray structures of the compounds were solved by direct methods from diffractometer data.4d: 2‐thia‐3,3‐dimethyl‐4R‐(t‐butyloxycarbonylmethylene)carboxylate‐5,7‐diaza‐6‐oxo‐8R‐phenylacetamido‐bicyclo‐1R‐[3,3,0]octane, C22H29N3O6S, monoclinic, space group P21; cell dimensions: a=13.625(6), b=8.344(3), c=10.656(3)Å, β=95.18(3)°; V=1206.4(8)Å3, Dx=1.28 gcm−3 for Z=2. 1646 measured and 1098 observed reflections. Final R=0.067.5d: 2‐thia‐3,3‐dimethyl‐4R‐(t‐butyloxycarbonylmethylene)carboxylate‐5,7‐diaza‐6‐oxo‐7‐benzoyl‐8R‐phenylacetamido‐bicyclo‐1R‐[3,3,0]octane, C29H33N3O7S. H2O, monoclinic, space group P21; cell dimensions: a=11.074(4), b=6.255(1), c=21.801(6)Å, β=92.49(3)°; V=1508.5(8)Å3; Dx=1.29 gcm−3 for Z=2.2257 measured and 1836 observed reflections. Final R: 0.071.Small but significant changes of bond lengths in the diaza pentagonal cycle are probably due to the benzoyl substituent.
Synthesis of α‐(2‐Hydroxy‐2, 2‐Dimethylethyl)‐ω‐Methyl‐, and of α ω‐Bis (2‐Hydroxy‐2,2‐Dimethylethyl) Polyethylene Glycol
Authors: van Den Berge L. , Tavernier D. , Anteunis M. 
Published: September 2010

AbstractThe transformation of the end groups of polyethylene glycol to the O‐ethoxycarbonylmethyl derivative 2 is described, using either a base‐catalysed reaction with ethyl bromoacetate or an acid‐catalysed reaction with ethyl diazoacetate. Compound 2 was reacted with methyllithium or methylmagnesium iodide to yield the α, ω title compounds. The end hydroxyl grouping of polyethylene glycol monomethyl ether was similarly transformed. Yields, experimental convenience and eventual side reactions are discussed.
The Determination of Cadmium in Sewage Sludge of Domestic Origin by Means of ion Exchange Combined with ICP‐AES and Ion Exchange Combined with GF‐AAS
Authors: Taylor P. D. P. , Desmet B. , Dams R. 
Published: September 2010

AbstractThis paper describes the determination of Cd in a sample of sewage sludge of domestic origin. The analysis result obtained was used by the European Community Bureau of Reference (BCR) for the certification of the Cd content in this sample (BCR N° 144). The combination of the low Cd content and the difficult environmental matrix made the certification especially arduous. In this study, a suitable sample digestion and chemical separation method is described. Inductively Coupled Plasma‐Atomic Emission Spectrometry (ICP‐AES) and Graphite Furnace‐Atomic Absorption Spectrometry (GF‐AAS) are both used as means of detection. The values obtained are compared with the certified value as well as with two other values stemming from nuclear analytical techniques which are quasi unaffected by contamination.
Remote‐Controlled System for the Production of [1‐11C] Palmitic Acid
Authors: Goethals P. , Slegers G. 
Published: September 2010

AbstractA semi‐automated production unit is developed for the routine production of [1‐11C] palmitic acid via carbonation of n‐pentadecyl magnesium bromide with 11CO2. The labeled compound is synthesized to study the myocardial metabolism by means of positron emission tomography. Chemical, radiochemical and pharmaceutical control showed that the product is suitable for human i.v. administration. In 35 min 40 to 60 mci of [1‐11C] palmitic acid are produced in a final isotonic solution of 12 ml.
Accurate Analytic Fitting of Pixe Spectra
Authors: Maenhaut W. , Vandenhaute J. 
Published: September 2010

AbstractThe computer program AXIL has been modified so that it describes complex PIXE spectra in a more accurate way. The modifications include a new representation of the absorption (detection efficiency) term, a non‐linear energy calibration, and a sum peak modeling routine. The new version (AXIL‐84) is described in some detail and several examples are given to illustrate its present performance.
The Voltammetric Behaviour of the System Bi(III)/Bi(Hg) IN 4M HClO4
Authors: Bogaert M. , Temmerman E. , Kiekens P. , Verbeek F. 
Published: September 2010

AbstractThe voltammetric behaviour of Bi(III)/Bi(Hg) in 4M HClO4 has been studied with the aid of DC polarography and cyclic voltammetry. The reduction mechanism is complex. The electrochemical reduction is preceded by a homogeneous chemical reaction and the three‐electron reaction has to be considered as three successive one‐electron transfers. Quantitative results relative to as well the electrochemical as the chemical reaction are obtained.
Études Structurales En Série Helicenique. IV. Structures Du Fluoro‐1 Heptahelicene C30H17F Et Du Cyano‐17 Fluoro‐1 Heptahelicene C31H16Fn
Authors: van Meerssche M. , Declercq J. P. , Soubrier‐Payen B. 
Published: September 2010

AbstractThe structures of the title compounds have been determined by X‐ray single crystal diffractometry.The crystal data are as follows: 1F‐|7|helicene C30H17F, triclinic, space group p1, a=8.696(2), b=16.547(6), c=14.377(4)Å, α=74.01(3), β=100.44 (2), γ=91.59(3)°, Z=4; 1F‐17CN‐|17|helicene C32H16FN, monoclinic, space group C2, a=48.980(17), b=9.678(6), c=17.456(6)Å, β=90.69(3)°, Z=16. The helicenic fragment of the molecules are very similar in structure to heptahelicene itself.
Nitration de Pyridinobenzotetraazapentalenes
Authors: Maquestiau A. , Flammang‐Barbieux M. , Vilain E. 
Published: September 2010

AbstractThe orientation specificity for nitration reaction of [3,2‐b] pyridino and [2,3‐b] pyridino‐1,3a,6,6a− and 1,3a,4,6a‐tetraazapentalenes is discussed.
Chimio‐ et Régiosélectivités de la Cycloaddition de Diarylnitrilimines sur la Thieno(2,3‐c)Pyridine
Authors: Fathi Toufik , An Nguyen Dinh , Schmitt Gérard , Vebrel Joël , Laude Bernard 
Published: September 2010

AbstractDiaryinitrilimines 2 react regiospecifically on the CN double‐bond of thieno(2,3‐c) pyridine 1 to give in a first step a cycloadduct 3 DANI 2 react regiospecifically on the enaminic double‐bond of the cycloadduct 3 to give the diadduct 4.
Reversible Ring‐Opening Reaction of a Triazolobenzodiazepine, Triazolam, in Acidic Media
Authors: Jiménez R. M. , Alonso R. M. , Vicente F. , Hernández L. 
Published: September 2010

AbstractThe hydrolytic reaction of Triazolam in acidic solution at room temperature was studied spectrophotometrically. The reversible azomethine bond cleavage reaction of Triazolam took place and an open‐ring compound was in equilibrium with a closed‐ring compound. Kinetic studies indicate that the hydrolysis reaction is first order with respect to proton concentration. The indirect determination of acid‐dissociation constant was carried out from the kinetic data. The pKa value (2.19) is similar to the one obtained (2.26) from spectrophotometric acid‐base studies. The shift of peak potential of the Triazolam obtained by differential pulse polarography also showed the acid hydrolysis of the compound.
Crystal Structure and Conformation of Short Linear Peptides: Part III: Glycyl‐L‐Leucyl‐L‐Tyrosine 2.5 Hydrate Dimethylsulfoxide Solvate
Authors: Wu S. , Tinant B. , Declercq J. P. , van Meerssche M. 
Published: September 2010

AbstractC17H25N3O5 (CH3)2SO2 5H2O, Mr = 474.6, triclinic, P1, a = 11.990(4), b = 12.380(11), c = 9.342(3)Å, α = 83.92(5), β = 79.99(3), γ = 84.60(6)Å, V = 1241(1)Å1, Z = 2, Dx = 1.27 gcm−3, MoKa, λ = 0.71069 Å, μ = 1.38 cm‐1, F(000) = 1020, T = 291K, R = 0.056 for 2854 observed reflections. The title peptide (GLT) adopts an anti‐parallel pleated‐sheet conformation, very similar to that found in the copper (II) complex of this peptide(1). This confirms that the conformation of this peptide is affected only very slightly by the solvatation. The Leu side‐chain of molecule B takes a conformation characterized by X1 = ‐178°, X21 = 152° and X22 = ‐85°, which is only observed in D‐Leu residue.
Two‐Dimensional Nuclear Magnetic Resonance Study of the Conformation of The Tetrapeptide Z‐His‐Trp‐Ser‐TyrOH
Authors: Zhang Weiguo , Anteunis Marc J. O. , Borremans Frans A. M. 
Published: September 2010

AbstractTwo‐dimensional (2D) NMR homonuclear correlation (COSY, Relayed COSY and Delayed COSY) and 2D NOESY techniques were applied to obtain the unambiguous assignments of the individual protons of Z‐His‐Trp‐Ser‐TyrOH, a component tetra‐peptide of LH‐RH, in deuterated dimethyl sulfoxide solution (DMSO). The observed 2D‐NOE connectivities, the chemical shift and coupling data, and the amide NH chemical shift temperature gradients are consistent with a random coil backbone conformation.
Transformation of Sucrose ‐ Re‐Examination of Octamolar Tosylation of Sucrose
Authors: Sharma N. K. , Norula J. L. , Anteunis Marc J. O. 
Published: September 2010

AbstractOctamolar tosylation of sucrose with p‐toluenesulfonyl (tosyl)chloride has been re‐examined under different conditions to obtain octa‐O‐tosyl sucrose as a single entity. It was observed that tosylation of sucrose with 8 moles of tosyl chloride in pyridine at 0°C, ‐5°C and ‐15°C afforded octa ‐O‐tosyl sucrose, hepta‐O‐tosyl sucrose, hexa‐O‐tosyl sucrose and penta‐O‐tosyl sucrose respectively in varying amounts. The products obtained were purified by column chromatography and the structures of the chromatographically pure tosyl esters were confirmed by high resolution 1H NMR spectra of their respective acetates.
Synthèse et Étude de RMN1H en Présence de l'Eu (fod)3 des Pyrazolo[1,5,4‐ef] Benzodiazepine ‐1,5 Ones‐6(1)
Authors: Benchidmi M. , Essassi E. M. 
Published: September 2010

AbstractCondensation of β‐Ketoesters with 7‐aminoindazoles have been examinated. The structure of pyrazolo [1,5,4‐ef] benzodiazepin ‐6‐ ones, obtained from ethylacetylacetate have been established by mass spectrometry and by 1H NMR in presence of Europium (fod)3.
Simple Preparations of Some Hydantoins of Phenylalanine and α‐MePhe and Their Chiral Stability During N3‐Alkylation. A Route to the Synthesis of Chiral Amines
Authors: Anteunis M. J. O. , Spiessens L. , De Witte M. , Callens R. , Reyniers Fr. 
Published: September 2010

AbstractPreparations of chiral‐pure hydantoins derived from L‐Phe and L‐α‐MePhe are re‐visited. A one step quantitative route for 5‐benzyl‐5‐methyl hydantoin is obtained by melting α‐MePhe with ureum. L‐Phe‐hydantoin could not be alkylated at N‐3 with conservation of the chirality at C‐5. Diastereomers resulting from asymmetric alkyl groupings implanted at N‐3 can be separated by crystallization in aqueous medium. The N‐3 alkylated hydantoins can be hydrolyzed in high yields with Ba (OH)2. This allows the preparation of enantiomeric pure amines such like 2‐methylbutylamine and 2‐hydroxypropylamine via N‐3 alkylation of the chirally‐stable hydantoin of α‐MePhe followed by enantiomeric resolution and hydrolysis.
Potentiometric Investigation of the Complexes Formed by Citraconate in Water at Ionic Strength I=1 and I=3
Authors: Bouserie Frank L. G. , Thun Harry P. 
Published: September 2010

AbstractA potentiometric study is made at 25°C of the dissociation of citraconic acid in aqueous sodium perchlorate solutions of ionic strength 1 and 3.
Crystal Structure and Conformation of Short Linear Peptides: Part VII: L‐Leucyl‐L‐Tyrosyl‐L‐Leucine Monohydrate
Authors: Wu S. , Declercq J. P. , Tinant B. , van Meerssche M. 
Published: September 2010

AbstractC21H33N3O5H2O, Mr = 425.52, monoclinic, P2, a = 13.387(5), b = 15.452 (7), c = 13.198(5) Å, β = 115.74(3)°, V = 2459(2)Å3, Z = 4, Dx = 1.15 g. cm−3, MoKα, λ = 0.71069 Å, μ = 0.91 cm−1, F (000) = 920, T = 291K, R = 0.071 for 2348 observed reflections. The two independent molecules have quite different conformations. An antiparallel‐chain pleated sheet structure is observed at Tyr residue of molecule A and at Leu(2) residue of molecule B, characterized by (ϕ, Ψ) angles of (‐130°, 121°) and of (‐134°, 140°) respectively. A poly‐Gly‐II conformation is observed at Leu(2) level of molecule A and at Tyr level of molecule B with (ϕ, Ψ) values of (‐114°, 159°) and of (‐83°, 137°) respectively. The Leu(2) side chain of molecule A takes an unusual conformation with (X1, X21, X22) angles of (‐74°, 48°, ‐172°). The other side chains have normal conformations.
Trans‐Diaqua‐Bis[Dimethylglyoximato(1‐)‐N, N′] Cobalt(III) Perchlorate: Crystal Structure and Local Disordering Effects
Authors: Pyckhout W. , Lenstra A. T. H. , Tyrlik S. K. 
Published: September 2010

Abstract[Co(C4H7N2O2)2 (H2O)2]ClO4, Mr = 424.7, C2/c, a = 21.344(5), b = 5.980(2), c = 13.707(2)Å, β = 113.08(1)°, V = 1609.5(1)Å3, Z = 4, Dx = 1.744 Mg m−3, Mo Kα, λ = 0.71069Å, μ = 1.28 mm−1, F(000) = 872, room temperature, wR = 0.068 for 975 reflections.The perchlorate ion is disordered. Models assuming completely free rotation and rotation around one Cl‐O vector could be rejected. A description using occupancy factors for the O atoms proved satisfactory. The Co is octahedrally coordinated by 4N atoms in the equatorial plane and by two axial H2O ligands, the Co‐O (water) = 1.900(3)Å. Inequalities in the bond lengths of a dimethylglyoximato ligand are in accord with expected trends when one of the oxime groups is protonated and the other is negatively charged. Two short intramolecular hydrogen bridges are observed with O—O distances of 2.53 Å and 2.60 Å.
Molecular Structure Analysis of Benzamide Neuroleptics and Analogs. XII: (Exo)‐2, 3‐dimethoxy‐N‐[8]‐(Phenylmethyl)‐8 ‐AZA ‐Bicyclo [3.2.1] Oct ‐ 3 ‐ YL] Thiobenzamide, Hydrochloride
Authors: Collin S. , Baudoux G. , Evrard G. , Durant F. 
Published: September 2010

AbstractC23H28N2O2S.HCLI2 (two molecules in the asymmetric unit), Mr = 866.0, monoclinic, P21/c, a = 21.523(1), b = 13.274(1), c = 15.679(2) Å, β = 94.19(1)*, V = 4467.54 Å3. Z = 4, Dc = 1.29 g·cm−3, Cu Kα, λ = 1.54178 Å, μ = 24.34 cm−1. F(000) = 1840, final Rw = 0.05 for 3799 observed reflections (1 ≥ 2.5 σ(1)). Bond distances and angles show a delocalization of the Π orbitals in the thioamide moiety without significant delocalization to the phenyl ring. Comparison with a very active analog, the tropepride, suggests that the decrease of the title compound antipsychotic activity is due to the lack of a strong intrabenzamidic hydrogen bond which is present in the active benzmides.
Calculation of Aluminum Speciation in the Presence of Inorganic Complexing Agents
Authors: Courtyn E. , Nagels M. , Vandecasteele C. , Yu Z‐Q. , Dams R. 
Published: September 2010

AbstractEquilibrium concentrations of inorganic complexes of Al in solutions containing varying amounts of sulfate and fluoride at different pH values are calculated. Although the proposed model is simplified and does not take into account the precipitation of aluminum hydroxide, it shows clearly which are the dominating species in the pH range from 3 to 6.
Détermination des Constantes D'Acidité des Acides Mercapto‐2 Pyridinecarboxylique‐4 et Mercapto‐4 Pyridinecarboxylique‐2
Authors: Thunus L. , Lejeune R. , Delarge J. 
Published: September 2010

AbstractUV and potentiometric studies on 2‐(or 4−) mercapto‐4‐(or‐2−) pyridinecarboxylic acid are made. Estimation of aromatic and non aromatic species is done by derivative spectroscopy and acidity constants are found. Aromaticity in pyridine derivatives are discussed.
Synthèse de 2,3‐Dihyoro‐7H‐Pyrazolo [3,4‐b] Pyridine‐3‐Ones
Authors: Maquestiau A. , Vanden Eynde J.‐J. 
Published: September 2010

AbstractReactions between 5‐anilino‐2,4‐dihydro‐2‐phenyl‐3H‐pyrazol‐3‐one and β‐dicarbonyl compounds yield 2,3‐dihydro‐2,7‐diphenyl‐7H‐pyrazolo [3,4‐b] pyridin‐3‐ones, products which were not described previously.Structures of bicyclic derivatives obtained from unsymmetrical β‐dicarbonyl precursors were determinated by means of 1H NMR and IR data.
Hydrodenitrogenation of Decahydroquinoline Over Carbon‐Supported Transition Metal Sulfide Catalysts
Authors: Sudhakar C. , Eijsbouts S. , De Beer V. H. J. , Prins R. 
Published: September 2010

AbstractThe catalytic properties of the first, second and third row transition metal sulfides supported on activated carbon (TMS/C) were investigated for the hydrodenitrogenation of decahydroquinoline in micro‐autoclaves at 50 bar total pressure and at 623 K or 653 K. Excluding vanadium sulfide, the first row TMS/C catalysts had very low activity and showed no periodic trend. On the other hand, second and third row TMS/C catalysts were quite active and showed volcano‐type periodic trends, with maxima at Rh and Ir sulfides respectively. These periodic trends were very similar to those observed earlier for the TMS/C catalysts in the hydrodenitrogenation of quinoline and in the hydrodesulfurisation of thiophene.
An In‐Situ Mössbauer Study on the Formation and Stability of the Fe‐Mo‐S Phase in Carbon‐Supported Iron Molybdenum Sulfide Hds Catalysts
Authors: Ramselaar W. L. T. M. , Crajé M. W. J. , Gerkema E. , De Beer V. H. J. , van Der Kraan A. M. 
Published: September 2010

AbstractThe transition of an oxidic FeMo/C precursor into the actual active sulfide catalyst is studied by means of in‐situ Mössbauer spectroscopy. It is found that the composition of the sulfided catalyst is influenced by the sulfidation method applied. A correlation between the spectral contribution of a mixed Fe‐Mo sulfide (Fe‐Mo‐S) phase and the activity for thiophene HDS is demonstrated.
H/D isotope effect in γ‐irradiated C10H22/C10D22 mixtures at 4 K deduced by studying dimeric products by gas chromatography
Authors: Tilquin B. 
Published: September 2010

AbstractThe dimer products formed upon γ‐irradiation at 4 K of n‐decane‐d22 doped with 20% n‐decane‐h22 have been examined by means of capillary GLC coupled with mass spectrometry. Analysis of the results indicates that protiated alkyl radicals are selectively formed. This confirms the data obtained by radiolysis at 77 K. The selective abstraction of hydrogen from a C‐H bond on the solute molecules by the attack of D atoms which are formed by the radiolysis, occurs at 77 K. However, at 4 K, data from IWASAKI suggest an other explanation. The primary process is not selective but conversion of deuterated to protiated alkyl radicals takes place at 200 K.
Direct determination of selenium in whole blood with electrothermal A. A. S. and deuterium arc background correction
Authors: Deschuytere M. A. , Robberecht H. J. , Deelstra H. 
Published: September 2010

AbstractDirect determination of selenium in human whole blood is carried out using graphite furnace atomization absorption spectrometry. Interferences of inorganic ions, especially iron, are eliminated by using a molybdenum coated furnace and a L'vov platform. Different oxydation states of selenium revealed the same results. By comparison with hydride generation atomic absorption spectrometry and fluorimetry after wet acid digestion it can be concluded that the described procedure resulted in accurate values for selenium concentrations in small volumes of human whole blood.
Isolation of factor a (virginiamycin M1) and factor B (mixture of Vs1 and Vs4) from a commercial feed additive formulation
Authors: Sharma N. K. , Hosten N. , Anteunis M. J. O. 
Published: September 2010

AbstractVirginiamycins S (mixture of VS1 and VS4) next to Virginiamycin M (VM1) were isolated by a simple selective extraction method followed by recrystallization, starting from a commercially available formulation, marketed as feed additive.
Carboxymethyloximation of keto substrates. A useful grafting procedure applied on virginiamycin factors A & B
Authors: Anteunis M. J. O. , Callens R. , Sharma N. K. 
Published: September 2010

AbstractVirginiamycins M1 and S1 (factors A & B) were converted to their corresponding carboxymethyl oximes 1 & 2 in quantitative yields. 1 was further conjugated with tryptophan methyl ester to obtain derivative 3 in high yield by using BOP‐Cl as coupling reagent. The compounds 1, 2 & 3 were fully characterized by I. R. and 1H NMR spectra. Carboxymethyloximation seems to be a practical strategy for the preparation of conjugates of biologically active ketonic substrates.
Structure Du Kotschyioside, Saponoside Nouveau Isole De Aspilia Kotschyi (Sch. Bip.) Oliv
Authors: Kapundu Mpuza , Penders André , Warin Roger , Delaude Clément , Huls Robert 
Published: September 2010

AbstractThe major component of the saponin mixture from leaves of Aspilia Kotschyi (Asteraceae) has been isolated as a peracetylated and cristalline derivative. Its structure has been established essentially by NMR spectroscopy including two dimensional NMR and shown to be : 3β‐0‐(4 deoxy‐α‐hex‐4 enopyranosyluronic acid) 3 1 α‐L‐rhamnopyranosyl, 28‐0‐β‐D‐glucopyranosyl oleanolic acid.The name “Kotschyioside” is proposed for this new saponin.
Structure of 4‐(N′‐Pivaloyl)‐D(L)‐Phenylalanyl‐D (L)‐Perhydro‐4H‐1, 4‐Thiazine‐3‐(N‐Methyl) Carboxamide Methanol Monohydrate in the Crystalline State
Authors: Wu S. , Tinant B. , Declercq J. P. , van Meerssche M. , Borremans F. A. M. , Anteunis M. J. O. 
Published: September 2010

AbstractA crystal of the homochiral isomer of N‐Piv‐Phe‐(γS) Pec‐NHMe. CH3OH. H2O is subjected to an X‐ray diffraction analysis. C20H29N3O3S. CH3OH. H2O, Mr = 441.58, triclinic, P1, a = 12.981(2), b = 9.939(1), c = 11.345(1) Å, α = 75.05(1)°, β = 63.15(1)°, γ = 71.46(1)°. Z = 2, V = 1226.8(3) Å3, Dx = 1.20 g. cm−3, CuKα, λ = 1.54178 Å, μ = 14.31 cm−1, F (000) = 476, T = 291K, R = 0.058 for 3875 observed reflections. The data reveal a molecular conformation with all trans amide bonds, in an “open form” (ϕ1, ϕ1, ϕ2, ϕ2 = 123.8°, −81.9°, 120.4°, −23.1°) without intramolecular hydrogen bond, stabilized in a crystal environment of strong intermolecular H‐bonding.
Étude Sterochimique En Série Perhydrocyclohepta |b| Furanne
Authors: Dolmazon R. , Albrand M. , Henry R. 
Published: September 2010

AbstractConfigurations and probable conformations for the cis ‐ perhydrocyclohepta |b| furan‐3‐ols and perhydrocyclohepta |b| furan‐3‐ones obtained in this study are inferred from their 1H‐NMR and IR spectra. The energy difference between cis‐ and trans‐perhydrocyclohepta |b| furan‐3‐ one is virtually negligible.
Hexachlorodimedone: Ring opening and intramolecular substitution of halogen. Preparation of γ,δ‐Diketoacids and Esters
Authors: De Buyck L. , De Pooter H. , Schamp N. 
Published: September 2010

AbstractThe β‐dione system of 2, 2, 4, 4, 6, 6‐hexachloro‐5, 5‐dimethyl‐1, 3‐cyclohexanedione (1) is cleaved by weak base in methanol or aqueous organic solvent. The intermediate enolate ester 3a (resp. the carboxylate) is competitively protonated or chlorinated by 1. Protonation was made exclusive with added acetic acid, while chlorination was made exclusive in the presence of chlorine or hypochlorite.The reactions in methanol were applied to prepare the δ‐ketoesters 3 (hexachloro) and 5 (heptachloro) in excellent yields. Haloform degradation of 5 (NaHCO3 in methanol) afforded dimethyl 2, 2, 4, 4‐tetrachloro‐3, 3‐dimethyl‐1, 5‐pentanedioate (6) while 3 was easily cyclised to the stable enolether 4 by the same reagent.In aqueous solvent (acetic acid, dioxan or isopropanol) the ring opening of 1 was followed by a remarkably rapid intramolecular substitution of halogen by the carboxylate function, giving rise to y‐butyrolactones and the corresponding γ,δ‐diketoacids 8 and 14.
Investigation of some neba ‐ perchlorate electrodes for use in physicochemical measurements
Authors: De Poorter J. , Thun Harry P. 
Published: September 2010

AbstractLiquid membrane electrodes sensitive to perchlorate anions are prepared by using solutions of N‐ethylbenzothiazole‐2,2′ azaviolene perchlorate in 1,2‐dichlorobenzene or β,β′‐dichlorodiethylether. The behaviour and the analytical possibilities of these electrodes were examined at 25°C.
Novel oxidation of 1,2‐Dibenzylhydrazines with carbon tetrachloride
Authors: Kano Kunio , Anselme Jean‐Pierre 
Published: September 2010

Abstract1,2‐Dibenzyhydrazines are cleanly oxidized to the corresponding ω,ω'‐azotoluenes by carbon tetrachloride; carried out under phase‐transfer conditions in the presence of sodium carbonate, the new reaction provides a clean, inexpensive, nearly quantitative route to the azotoluenes.