bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYSIS OF AGE-RELATED INCIDENCE (BY CIRCULATION) OF AGE-ASSOCIATED PATHOLOGY IN 2018–2023 ON THE EXAMPLE OF THE MUNICIPAL POLYCLINIC OF SAINT-PETERSBURG
Authors: Сагинбаев У.Р. , Рукавишникова С.А. , Ахмедов Т.А. , Давыдова Е.П. , Меркулова И.В. 
Published: June 2024

С 25–30 лет начинает повышаться вероятность развития патологических процессов, ассоциированных со старением. Возраст-ассоциированные заболевания (ВАЗ) — гетерогенная группа патологий, вероятность развития которых повышается по мере старения. В клиническом плане раннее развитие ВАЗ тождественно преждевременному старению со всеми вытекающими последствиями. Своевременное таргетное выявление ВАЗ позволит замедлить возрастные процессы. Для изучения особенностей повозрастной заболеваемости (по обращаемости) возраст-ассоциированной патологией в исследование были включены 5 600 лиц с впервые установленным диагнозом, обращавшихся в муниципальную поликлинику Санкт-Петербурга в 2017–2023 гг. При исследовании обнаружена гетерогенность сроков манифестации ВАЗ на популяционном уровне. Кроме того, медианный возраст пациентов был сопоставим со значением разработанного возрастного индекса заболеваемости, что служит основанием для продолжения исследований в целях всеобъемлющей оценки свойств и ограничений рассматриваемого показателя.
From the age of 25–30, the likelihood of developing pathological processes associated with aging begins to increase. Age-associated diseases (AAD) are a heterogeneous group of pathologies that are more likely to develop as they age. Clinically, the early development of AAD is identical to premature aging with all the ensuing consequences. Timely targeted detection of AAD will slow down age-related processes. In order to study the peculiarities of age-related morbidity (by circulation), age-associated pathology, the study included 5 600 people with a newly diagnosed diagnosis who applied to the municipal polyclinic of St. Petersburg in 2017–2023. During the study, heterogeneity of the timing of the manifestation of AAD at the population level was found. In addition, the median age of patients was comparable to the value of the developed age-specific incidence index, which serves as a basis for continuing research in order to comprehensively assess the properties and limitations of the considered indicator.
FRAILTY ASSESSMENT IN GERIATRIC ONCOLOGY
Authors: Лаптева Е.С. , Арьев А.Л. 
Published: June 2024

Представлен обзор по использованию комплексной гериатрической оценки (КГО) и ее компонентов в онкологии. Продемонстрирована доказательная база увеличения онкологической заболеваемости у пожилых людей во всем мире. Тактика лечения пожилых людей с данной патологией является сложной задачей. Многими авторами доказано, что КГО является сильным предиктором нежелательных явлений у пациентов старше трудоспособного возраста со злокачественными онкологическими заболеваниями. КГО рекомендована в онкологической практике по многим причинам: верификация проблем со здоровьем, обычно не выявляемых при рутинном онкологическом обследовании, проведение неонкологических вмешательств, а также изменение плана лечения онкологического заболевания. КГО является золотым стандартом в гериатрической онкологии для выявления пациентов с высоким риском неблагоприятных исходов и оптимизации лечения злокачественных новообразований, включая тактику общего ведения больного. Тем не менее, можно констатировать, что окончательная точка в поиске научно обоснованных и эффективных инструментов оценки хрупкости в практике гериатрической онкологии еще не поставлена. Сделан вывод, что разработка новых шкал и индексовых показателей, а также применение модели КГО в целом может обеспечить адекватную помощь онкологическим больным гериатрического профиля.
A review of the use of comprehensive geriatric assessment and its components in oncology is introduced. The evidence base for the increasing incidence of cancer in the elderly worldwide also presented. The management of older adults with cancer is challenging. Comprehensive Geriatric Assessment (CGA) has been shown by many authors to be a strong predictor of adverse events in geriatric oncology patients. CGA is recommended in oncology practice for many reasons: to identify health problems not usually detected in routine oncologic screening, to perform non-oncologic interventions, and to modify the cancer treatment plan. Comprehensive geriatric assessment is the gold standard in geriatric oncology for identifying patients at high risk for adverse outcomes and optimizing cancer treatment and overall management. Nevertheless, it can be stated that the final point in the search for evidence-based and effective frailty assessment tools in the practice of geriatric oncology has not yet been reached. It is concluded that the development of new scales and index scores, as well as the application of the CGA model in general, can provide adequate care for elderly cancer patients.
IMPAIRED HEMOSTASIS IN ELDERLY AND SENILE PATIENTS WITH MESENTERIC THROMBOSIS IN COVID-19
Authors: Кадников Р.В. , Васильченко М.В. , Рукавишников А.С. 
Published: June 2024

При лечении коронавирусной инфекции необходимо учитывать ее течение, изменения в системе кровообращения и нарушения, которые приводят к ухудшению состояния и дальнейшим осложнениям. Нарушение гемостаза при COVID-19 играет важную роль в этиологии и клинических проявлениях заболевания. Умение выявлять факторы и группы риска развития тромботических осложнений, способность динамически интерпретировать показатели периферической крови и коагулограммы, знание диагностических критериев возможных нарушений гемостаза (например, синдром диссеминированного внутрисосудистого свертывания, сепсис-ассоциированная коагулопатия, антифосфолипидный синдром, гемофагоцитоз и гиперкоагуляционный синдром) необходимы для определения показаний к проведению теста. Важно дифференцировать назначение клинически обоснованной терапии (включая антикоагулянты и компоненты крови), которая влияет на сложность общего лечения и прогноз для пациентов с COVID-19. Данная статья представляет собой обзор литературы по теме нарушения гемостаза у пациентов пожилого и старческого возраста с мезентериальным тромбозом при COVID-19 за последние несколько лет.
In the treatment of coronavirus infections, it is important not only to understand the course of the disease, but also to understand what is happening in the human body, especially in the circulatory system, that is, which disorders lead to deterioration and further complications. Hemostasis disorder in COVID-19 plays an important role in the etiology and clinical manifestations of the disease. The ability to identify factors and risk groups for the development of thrombotic complications, the ability to dynamically interpret peripheral blood parameters and coagulograms, knowledge of diagnostic criteria for possible hemostasis disorders (for example, DIC syndrome, sepsis-associated coagulopathy, antiphospholipids, hemophagocytosis and hypercoagulation syndrome) are necessary to determine the indications for the test. Differentiated prescribing of clinically justified therapy (including anticoagulants and blood components) is important, which determines the complexity of treatment and prognosis for patients with COVID-19. This article is a review of the literature on the topic of hemostasis disorders in elderly and senile patients with mesenteric thrombosis in COVID 19 over the past few years.
A complexidade de tarefas de leitura e produção escrita: uma análise dialógica.
Authors: Gomes Maíra Da Silva 
Published: June 2024

Partindo de uma perspectiva dialógica de linguagem, este artigo tem o objetivo de discutir a complexidade de tarefas integradas de leitura e produção textual do Exame Celpe-Bras. Os procedimentos metodológicos incluem uma análise estatística, a análise do texto-base da tarefa e das características do enunciado, que estabelece uma situação comunicativa e orienta para os propósitos de leitura e de escrita. Os resultados do estudo sugerem que a complexidade decorre principalmente da relação entre propósito de escrita e propósito de leitura. Assim é a partir das características da situação comunicativa estabelecida pelo enunciado (interlocutores, propósito, assunto e suporte) que os participantes se engajam na atividade, buscando informações na leitura do texto-base. As características do texto para leitura parecem influenciar na complexidade das tarefas integradas. Algumas das conclusões deste estudo revelam que textos que apresentam informações mais difusas e com construção não linear (opinião- argumento – conclusão) apresentam maior complexidade.

Palavras-chave: Complexidade. Tarefas. Perspectiva dialógica.
As palavras na publicidade: uma análise de anglicismos em briefings
Authors: Dias Souza Monique , Eckert Kleber 
Published: June 2024

A Publicidade é a área que objetiva divulgar marcas e seus respectivos produtos e/ou serviços. Em sua organização interna, existe um documento que norteia todas as ações: o briefing; um termo da Língua Inglesa que comunica aos profissionais envolvidos informações como o tipo de material a ser criado, o seu prazo, suas dimensões e outras especificidades. Neste trabalho, de modo geral, objetivamos identificar nesses briefings a presença de neologismos de origem inglesa, visto que a Publicidade é constituída, desde a sua origem, com muita influência externa, especialmente a norte-americana. Além disso, buscamos promover uma aproximação entre os estudos neológicos e o gênero textual briefing, ou seja, a verificação da presença de estrangeirismos e a respectiva análise quanto à estrutura ortográfica e morfológica. Para alcançar esses objetivos, utilizamo-nos de uma metodologia que integra o quantitativo com o qualitativo: coletamos o corpus, estruturamos tabelas e quadros, consultamos dicionários, utilizamos fichas neológicas e analisamos o conteúdo de cada briefing selecionado. Por fim, verificamos que dos 60 candidatos a neologismos por estrangeirismos, 38 foram considerados de fato anglicismos, o que indica a influência estadunidense na área da Publicidade. Também concluímos que muitas palavras estão em processo de aportuguesamento e que os substantivos constituem a classe gramatical que mais importa palavras.

Palavras-chave: Publicidade. Anglicismo. Lexicologia.
APPLICATION OF EXPERIMENTAL METHODS TO IMPROVE SCIENCE LEARNING OUTCOMES OF CLASS V STUDENTS OF SDN 186 KARARAN ENREKANG DISTRICT
Authors: Mahara  , Imranah  
Published: June 2024

Penelitian menggunakan penelitian tindakan kelas. Subjek penelitian adalah peserta didik kelas V SDN 186 Karangan yang berjumlah 21 orang. Penelitian dilaksanakan dalam dua siklus dengan mengadopsi model Kemmis dan Mc.Taggart melalui dari tahapan merencanakan, pelaksanaan, pengamatan, dan refleksi. Teknik pengumpulkan data yaitu observasi, dokumentasi dan tes. Instrumen penelitian adalah lembar observasi dan tes hasil belajar. Hasil Penelitian ini menunjukkan bahwa penerapan metode eksperimen dalam proses pembelajaran untuk meningkatkan hasil pembelajaran IPA materi ekosistem di kelas V SDN 186 Karangan yang dilakukan selama dua siklus meningkat. Hal ini dilihat dari persentase rata-rata hasil belajar peserta didik setelah diterapkan metode eksperimen yaitu pada siklus I sebesar 57% dan pada siklus II sebesar 85%, hal ini memperlihatkan terdapat peningkatan sebesar 28%.
ANESTESIA EM CESARIANAS DE EMERGÊNCIA: DESAFIOS E PROTOCOLOS DE MANEJO
Authors: Ierardi Marcela Oliveira , Costa Allison Gonçalves Silva Dutra , Gomes Gustavo Ivankovic , Costa Fernando Vieira de Souza , Moura Humberto Wérneck Araújo , Marques Rebecca Nobre , Villarta Filippi Valentino Agostinho , Teles Stephanie Louise Ribicki , Rodrigues Pedro Henrique Taufer , Mrozinski Gabriela Nairana Pedroso , Bacco Luigi Alcântara , Montenegro Rogério Batista , Silva Carlos Renato Félix Garcia da , Silva Victor Borges da 
Published: June 2024

A cesariana de emergência é um procedimento obstétrico crucial realizado quando há uma ameaça iminente à vida da mãe ou do bebê. Nessas situações, a administração da anestesia apresenta desafios únicos que exigem decisões rápidas e precisas. A eficácia da intervenção anestésica, sustentada por protocolos bem estabelecidos, é fundamental para garantir a segurança e o bem-estar de ambos, mãe e bebê, em um momento de alta criticidade. Objetivo: Identificar os principais desafios anestésicos nessas situações críticas e desenvolver protocolos de manejo eficientes para garantir a segurança materna e fetal. Metodologia: Foram utilizadas as bases de dados Cochrane, Scielo e Pubmed, buscando artigos publicados entre os anos de 2018 e 2023, nos idiomas Português ou Inglês. Considerações Finais: A anestesia em cesarianas de emergência exige uma abordagem rápida e eficaz para garantir a segurança materna e fetal. Protocolos claros e baseados em evidências, juntamente com a capacitação contínua da equipe, são essenciais para o manejo adequado dessas situações críticas. A implementação de práticas anestésicas seguras e a prontidão em emergências obstétricas são fundamentais para otimizar os desfechos e assegurar o melhor cuidado possível.
Clinical significance and possibilities for correction of hyperammonemia in patients with atrial fibrillation
Authors: Pan A. A. , Zaikova-Khelimskaia I. V. , Alekseenko S. A. 
Published: June 2024

Introduction. Atrial fibrillation (AF) is the most common type of supraventricular tachyarrhythmia. Despite the established link between hyperammonemia and cardiac rhythm disorders, data on ammonia levels in patients with AF are currently lacking in both domestic and international medical literature.Aim. To assess the ammonia levels in the blood of patients with atrial fibrillation and evaluate the effectiveness of standard therapy combined with L-ornithineL-aspartate in patients with atrial fibrillation and hyperammonemia.Materials and methods. The study involved 88 patients with permanent or persistent forms of AF (47 women, 41 men, aged 69.9±2.2 years), who underwent assessment of ammonia levels in capillary blood (using the portable analyzer PocketChem BA PA 4140), as well as levels of fatigue and active attention using validated "Fatigue Assessment Scale" and "Number Connection Test". Among 36 selected patients with AF and hyperammonemia, undergoing a 10-day treatment course, two randomized groups were formed: the first group (n=18) received standard therapy (angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers, antiarrhythmic, diuretic, anticoagulant drugs), and the second group (n=18) received additional therapy (L-ornithine-Laspartate) to reduce hyperammonemia.Results. Hyperammonemia was detected in 79.55% of the 88 patients, with an average value of 146±5.45 µg/dL (normal up to 75 µg/dL). Ammonia levels in women (115.97±6.78 µg/dL) were significantly lower than in men (150.90±6.62 µg/dL) (p=0.001). During the standard therapy, ammonia levels in the first group did not change significantly (153.63±7.45 µg/dL to 161.53±9.55 µg/dL; p=0.103), active attention levels worsened (p=0.031), and mental fatigue progressed (p=0.06). The second group of patients showed a decrease in ammonia levels from 158.44±8.91 µg/dL to 123.94±11.9 µg/dL (p=0.035), improved active attention (p=0.002), and decreased fatigue (p=0.02).Conclusion. The results indicate the appropriateness of assessing ammonia levels in the blood of patients with atrial fibrillation and correcting hyperammonemia in this category of patients.
Establishing and clinically validating a machine learning model for predicting unplanned reoperation risk in colorectal cancer
Authors: Cai Li-Qun , Yang Da-Qing , Wang Rong-Jian , Huang He , Shi Yi-Xiong 
Published: June 2024

BACKGROUND
Colorectal cancer significantly impacts global health, with unplanned reoperations post-surgery being key determinants of patient outcomes. Existing predictive models for these reoperations lack precision in integrating complex clinical data.
AIM
To develop and validate a machine learning model for predicting unplanned reoperation risk in colorectal cancer patients.
METHODS
Data of patients treated for colorectal cancer (n = 2044) at the First Affiliated Hospital of Wenzhou Medical University and Wenzhou Central Hospital from March 2020 to March 2022 were retrospectively collected. Patients were divided into an experimental group (n = 60) and a control group (n = 1984) according to unplanned reoperation occurrence. Patients were also divided into a training group and a validation group (7:3 ratio). We used three different machine learning methods to screen characteristic variables. A nomogram was created based on multifactor logistic regression, and the model performance was assessed using receiver operating characteristic curve, calibration curve, Hosmer-Lemeshow test, and decision curve analysis. The risk scores of the two groups were calculated and compared to validate the model.
RESULTS
More patients in the experimental group were ≥ 60 years old, male, and had a history of hypertension, laparotomy, and hypoproteinemia, compared to the control group. Multiple logistic regression analysis confirmed the following as independent risk factors for unplanned reoperation (P < 0.05): Prognostic Nutritional Index value, history of laparotomy, hypertension, or stroke, hypoproteinemia, age, tumor-node-metastasis staging, surgical time, gender, and American Society of Anesthesiologists classification. Receiver operating characteristic curve analysis showed that the model had good discrimination and clinical utility.
CONCLUSION
This study used a machine learning approach to build a model that accurately predicts the risk of postoperative unplanned reoperation in patients with colorectal cancer, which can improve treatment decisions and prognosis.
Stakeholder engagement, government policy, and tourist satisfaction
Authors: Jumadi  , Adhifa Muhammad Nugroho Hariadi Nur , Amelia Amanda , Ashiva Devitri Salsa 
Published: June 2024

The tourism industry has a complex relationship between geography, and all-natural resources, human, so tourism can create problems in human life. Good management in the tourism industry can create benefits for the nation's economy such as foreign exchange income, business development, and employment opportunities. For the optimum goals, the tourism industry can establish good relations with stakeholders and government policy support. Aim to the research on the evaluation of the effect of stakeholder engagement in tourism development and government policy on tourist satisfaction in the Indonesian tourism industry. This research is based on quantitative to test the hypothesis affecting stakeholder engagement in tourism development and government policy on the Indonesian tourism industry. The sample size of the research 250 with propulsive sampling and the main instrument is a questionnaire. The data analysis to use examine hypothesis with structural equation modelling Amos 20 version. The result of the investigations shows that the stakeholder engagement in tourism development has not been able to provide a level of tourist satisfaction, but the government policies can be influenced by tourist satisfaction.
Infarto renal, un sitio atípico de embolismo como debut de fibrilación auricular. Reporte de caso y revisión de la literatura
Authors: Aguilar Medellín Dalia Fernanda 
Published: June 2024

La fibrilación auricular (FA) es la arritmia sostenida más común y su incidencia y prevalencia está aumentando en todo el mundo. La FA cumple los criterios de la tríada de Wirchow, que son necesarios para la formación de trombos: estasis sanguínea, disfunción endotelial y activación de la coagulación. Los acontecimientos clínicos relacionados con la trombosis se han atribuido esencialmente a la formación de trombos en la aurícula izquierda con el consiguiente embolismo a circulación cerebral y periférica. Presentamos un caso en un paciente con factores de riesgo cardiovascular por edad, sexo y comorbilidades, FA previamente subclínica, quien debuta con tromboembolismo de arteria renal derecha, ocasionando un infarto renal agudo, un sitio poco común dentro de los sitios de embolismo asociados a FA, con cuadro clínico poco específico, sesgado por lesión hepática benigna, el cual se documentó por angiotomografía, se inició terapia anticoagulante sistémica y antiplaquetaria local, con buenos desenlaces clínicos.
Verification of Astrometrically Accelerating Stars from Hipparcos and Gaia. I. Methodology and Application to HIP 44842
Authors: Makarov Valeri V. , Tokovinin Andrei 
Published: June 2024

Abstract
A large number of candidate binary stars with apparent acceleration on the sky has emerged from analysis of astrometric data collected by the Hipparcos, Tycho-2, and Gaia space missions. Although the apparent acceleration can serve as a relatively reliable indicator of binarity, it provides scarce information about the orbital and physical parameters of the components. With an emphasis on the search for stellar-mass black holes and neutron stars hidden in binary systems, we start a broader effort to characterize the most promising candidates using follow-up ground-based observations. Accurate quantification of orbital and physical parameters of systems with dim or invisible companions requires combination of Hipparcos, Gaia, and precision spectroscopic measurements. In this paper, we review the necessary steps in this implementation and describe the improved Hipparcos–Gaia sample of long-term astrometric accelerations, which includes correction of sky-correlated systematic errors using the vector spherical decomposition method. As an example, we study one Hipparcos star with a large acceleration, HIP 44842, where the companion is revealed to be a normal main-sequence star.
The AGORA High-resolution Galaxy Simulations Comparison Project. IV. Halo and Galaxy Mass Assembly in a Cosmological Zoom-in Simulation at z ≤ 2
Authors: Roca-Fàbrega Santi , Kim Ji-hoon , Primack Joel R. , Jung Minyong , Genina Anna , Hausammann Loic , Kim Hyeonyong , Lupi Alessandro , Nagamine Kentaro , Powell Johnny W. , Revaz Yves , Shimizu Ikkoh , Strawn Clayton , Velázquez Héctor , Abel Tom , Ceverino Daniel , Dong Bili , Quinn Thomas R. , Shin Eun-jin , Segovia-Otero Alvaro , Agertz Oscar , Barrow Kirk S. S. , Cadiou Corentin , Dekel Avishai , Hummels Cameron , Oh Boon Kiat , Teyssier Romain ,   The AGORA Collaboration
Published: June 2024

Abstract
In this fourth paper from the AGORA Collaboration, we study the evolution down to redshift z = 2 and below of a set of cosmological zoom-in simulations of a Milky Way mass galaxy by eight of the leading hydrodynamic simulation codes. We also compare this CosmoRun suite of simulations with dark matter-only simulations by the same eight codes. We analyze general properties of the halo and galaxy at z = 4 and 3, and before the last major merger, focusing on the formation of well-defined rotationally supported disks, the mass–metallicity relation, the specific star formation rate, the gas metallicity gradients, and the nonaxisymmetric structures in the stellar disks. Codes generally converge well to the stellar-to-halo mass ratios predicted by semianalytic models at z ∼ 2. We see that almost all the hydro codes develop rotationally supported structures at low redshifts. Most agree within 0.5 dex with the observed mass–metallicity relation at high and intermediate redshifts, and reproduce the gas metallicity gradients obtained from analytical models and low-redshift observations. We confirm that the intercode differences in the halo assembly history reported in the first paper of the collaboration also exist in CosmoRun, making the code-to-code comparison more difficult. We show that such differences are mainly due to variations in code-dependent parameters that control the time stepping strategy of the gravity solver. We find that variations in the early stellar feedback can also result in differences in the timing of the low-redshift mergers. All the simulation data down to z = 2 and the auxiliary data will be made publicly available.