bluuebunny/crossref_metadata_2025_split huggingface dataset:
Collagen as a Humidity Sensing Dielectric Material
Authors: Hudspeth Mathew A. , Kaya Tolga 
Published: August 2012

ABSTRACTThe motivating principle behind this research is the development of small, wearable devices that would use humidity and temperature measurements as metrics for health monitoring. If it is to be useful as a health monitoring tool, the device needs to respond quickly and predictably to changes in humidity. Collagen is shown to be a viable humidity sensing material for use in capacitive relative humidity (RH) sensors. As a natural by-product of meat and leather industries, collagen presents itself as an interesting and inexpensive alternative to polyimide dielectric sensing materials. We used gelatin, a partially hydrolyzed form of collagen, to allow for easier spin coating. We have successfully fabricated devices by depositing a collagen thin film (1.2 μm) via spin coating, followed by Au/Pd electrodes (60 nm) via sputter coating. A plastic mask made from a rapid prototyping machine was used during physical vapor deposition (PVD) to pattern electrodes. This simple method eliminates the need for the use of more complicated photolithography processes. Interdigitated electrodes (rather than parallel plate electrodes) form a 6 mm wide, planar capacitor structure that has little dependence on dielectric thickness and is not affected by dielectric swelling. Initial findings indicate that these devices very closely match the results of the commercial relative humidity sensor used for reference. The capacitance-humidity relationship is shown to be non-linear, with an average change of 3 fF for every 1% change in RH around 60% RH, and an average change of 7 fF for every 1% change in RH around 80% RH. In this work, we present the fabrication and characterization of these novel collagen-based relative humidity sensors.
The Effect of Walking on Postprandial Glycemic Excursion in Patients With Type 1 Diabetes and Healthy People
Authors: Manohar Chinmay , Levine James A. , Nandy Debashis K. , Saad Ahmed , Dalla Man Chiara , McCrady-Spitzer Shelly K. , Basu Rita , Cobelli Claudio , Carter Rickey E. , Basu Ananda , Kudva Yogish C. 
Published: August 2012

OBJECTIVE
Physical activity (PA), even at low intensity, promotes health and improves hyperglycemia. However, the effect of low-intensity PA captured with accelerometery on glucose variability in healthy individuals and patients with type 1 diabetes has not been examined. Quantifying the effects of PA on glycemic variability would improve artificial endocrine pancreas (AEP) algorithms.

RESEARCH DESIGN AND METHODS
We studied 12 healthy control subjects (five males, 37.7 ± 13.7 years of age) and 12 patients with type 1 diabetes (five males, 37.4 ± 14.2 years of age) for 88 h. Participants performed PA approximating a threefold increase over their basal metabolic rate. PA was captured using a PA-monitoring system, and interstitial fluid glucose concentrations were captured with continuous glucose monitors. In random order, one meal per day was followed by inactivity, and the other meals were followed by walking. Glucose and PA data for a total of 216 meals were analyzed from 30 min prior to meal ingestion to 270 min postmeal.

RESULTS
In healthy subjects, the incremental glucose area under the curve was 4.5 mmol/L/270 min for meals followed by walking, whereas it was 9.6 mmol/L/270 min (P = 0.022) for meals followed by inactivity. The corresponding glucose excursions for those with type 1 diabetes were 7.5 mmol/L/270 min and 18.4 mmol/L/270 min, respectively (P &lt; 0.001).

CONCLUSIONS
Walking significantly impacts postprandial glucose excursions in healthy populations and in those with type 1 diabetes. AEP algorithms incorporating PA may enhance tight glycemic control end points.
Que nous apprennent les BRIC ? Trois conjectures sur les économies émergentes
Authors: Vercueil Julien 
Published: August 2012

L’article part d’une définition exploratoire de la notion « d’économie émergente » pour s’intéresser aux quatre plus éminentes : le Brésil, la Russie, l’Inde et la Chine. Il formule trois conjectures à propos de ces économies, illustrées par les BRIC, malgré leurs différences : la cohérence institutionnelle est un préalable à l’émergence économique ; les trajectoires des BRIC ont été pilotées en temps réel ; il n’existe pas de voie optimale unique ( one best way ) de l’émergence économique.
L'impact de la microfinance : un enjeu politique au prisme de ses controverses scientifiques
Authors: Bédécarrats Florent 
Published: August 2012

L’idée s’est répandue que les évaluations d’impact rigoureuses seraient une nouveauté et que l’on viendrait de découvrir que la microfinance n’est pas la solution miracle contre la pauvreté. Cependant, l'analyse d'un corpus de 154 études montre qu’il s’agit d’une question ancienne qui n'a jamais été consensuelle. Cette analyse révèle l'essor que connaissent actuellement les approche évaluation quantitatives et académiques, au détriment d'approches plus opérationnelles.
Cutting Edge: Generation of Memory Precursors and Functional Memory CD8+ T Cells Depends on T Cell Factor-1 and Lymphoid Enhancer-Binding Factor-1
Authors: Zhou Xinyuan , Xue Hai-Hui 
Published: August 2012

Abstract
T cell factor (TCF)-1 and lymphoid enhancer-binding factor (LEF)-1 transcription factors have redundant roles in promoting thymocyte maturation. TCF-1 has been recently shown to critically regulate memory CD8+ T cell differentiation and persistence. The complete spectra of regulatory roles for TCF-1 and LEF-1 in CD8+ T cell responses are yet unknown. We conditionally targeted LEF-1, and by combination with germline deletion of TCF-1, we found that loss of both factors completely abrogated the generation of KLR G1loIL-7Rα+ memory precursors in effector CD8+ T cell populations in response to Listeria monocytogenes infection. Whereas CD8+ effectors deficient for TCF-1 and LEF-1 retained the capacity to express IFN-γ, granzyme B, and perforin, they were defective in TNF-α production. In the memory phase, the Ag-specific CD8+ T cells lacking TCF-1 and LEF-1 exhibited an effector phenotype and were severely impaired in secondary expansion upon rechallenge. Thus, TCF-1 and LEF-1 cooperatively regulate generation of memory precursors and protective memory CD8+ T cells.
The Welfare Impacts of Rural Electrification in Bangladesh
Authors: Khandker Shahidur R. , Barnes Douglas F. , Samad Hussain A. 
Published: August 2012

Lack of access to electricity has been considered a major impediment to the growth and development of rural economies. Thus, the provision of electricity and other forms of modern energy has been a priority for many development organizations, including the World Bank. However, few impact studies of electrification have taken the endogeneity of the grid connection into account. Using a cross-sectional survey conducted in 2005 of 20,900 rural households in Bangladesh, this paper examines the welfare impacts of household access to grid electricity after controlling for endogeneity bias. The econometric analysis shows that grid electrification has significant positive impacts on household income, expenditure, and education. The household gain in total income due to electrification is as high as 21 percent, with a 1.5 percentage point reduction in poverty per year. The results also suggest that the income and expenditure effects ofelectricity connection are higher for better-off households. doi: 10.5547/ISSN0195-6574-EJ-Vol33-No1-8
Fantastic Voyage: Designing Self‐Powered Nanorobots
Authors: Sengupta Samudra , Ibele Michael E. , Sen Ayusman 
Published: August 2012

AbstractThe use of swarms of nanobots to perform seemingly miraculous tasks is a common trope in the annals of science fiction.1 Although several of these remarkable feats are still very much in the realm of fiction, scientists have recently overcome many of the physical challenges associated with operating on the small scale and have generated the first generation of autonomous self‐powered nanomotors and pumps. The motors can be directed by chemical and light gradients, pick up and deliver cargo, and exhibit collective behavior.
ChemInform Abstract: Synthesis and Structural Characterization of ACu9Tt4 (A: Ca, Sr, Ba, Eu; Tt: Si, Ge, Sn) — Tetragonally Distorted Ternary Variants of the Cubic NaZn13 Structure Type. Improved Structure Refinement of SrCu2Ge2.
Authors: Schaefer Marion C. , Yamasaki Yuki , Fritsch Veronika , Bobev Svilen 
Published: August 2012

AbstractThe title compounds are synthesized from the elements using excess Cu and Si, Ge, or Sn as a flux (alumina crucibles, 1100 °C, 2 h).
ChemInform Abstract: Crystal Structures and Properties of Perovskites ScCrO3 and InCrO3 with Small Ions at the A Site.
Authors: Belik Alexei A. , Matsushita Yoshitaka , Tanaka Masahiko , Takayama‐Muromachi Eiji 
Published: August 2012

AbstractThe title compounds are prepared from stoichiometric mixtures of In2O3, Sc2O3, and Cr2O3 (Au capsule, 6 GPa, 1500 K, 2 h).
ChemInform Abstract: Enantioselective Organocatalytic Reductive Amination of Aliphatic Ketones by Benzothiazoline as Hydrogen Donor.
Authors: Saito Kodai , Akiyama Takahiko 
Published: August 2012

AbstractA highly enantioselective protocol for the reductive amination of aliphatic ketones with aromatic amines catalyzed by a chiral phosphoric acid is presented.
ChemInform Abstract: Selective Arene Functionalization Through Sequential Oxidative and Non‐oxidative Heck Reactions.
Authors: Schmidt Bernd , Elizarov Nelli 
Published: August 2012

AbstractA sequence of acetamide directed oxidative Heck reaction and deacetylation—diazotation—Heck coupling allows the removal of the acetamide group and its dual exploitation as a catalyst directing group and leaving group.
ChemInform Abstract: Copper‐Catalyzed Trifluoromethylation of Terminal Alkynes Using Umemoto′s Reagent.
Authors: Luo Dong‐Fen , Xu Jun , Fu Yao , Guo Qing‐Xiang 
Published: August 2012

AbstractThe reaction proceeds under mild conditions to give trifluoromethylated alkynes with tolerance of a variety of functional groups.
ChemInform Abstract: Chemoselective Reduction of Nitrobenzenes to Aminobenzenes Having Reducible Groups by a Titanium(IV) Oxide Photocatalyst under Gas‐ and Metal‐Free Conditions.
Authors: Imamura Kazuya , Hashimoto Keiji , Kominami Hiroshi 
Published: August 2012

AbstractThe title reaction is performed in the presence of oxalic acid as a hole scavenger without the use of a precious metal or a reducing gas.
ChemInform Abstract: Asymmetric Nucleophilic Monofluorobenzylation of Carbonyl Compounds: Synthesis of Enantiopure vic‐Fluorohydrins and α‐Fluorobenzylketones.
Authors: Arroyo Yolanda , Sanz‐Tejedor M. Ascension , Parra Alejandro , Garcia Ruano Jose Luis 
Published: August 2012

AbstractAsymmetric addition of in situ generated chiral α‐fluoro‐γ‐sulfinylbenzyl carbanion towards aromatic (II) and aliphatic aldehydes (VI) proceeds with complete control of facial selectivity at the carbanion and with moderate to high anti‐diastereoselectivity to afford the product fluorohydrins in up to 92% d.e.
ChemInform Abstract: Zinc Acetate as a Catalyst for the Hydroacylation Reaction of Azodicarboxylates with Aldehydes.
Authors: Qin Yuancheng , Zhou Dan , Li Mingjun 
Published: August 2012

AbstractZn(OAc)2 is an effective catalyst for the title hydroacylation, tolerating a variety of functional groups and affording the corresponding products in good to excellent yields.
ChemInform Abstract: β‐Cyclodextrin Immobilized onto Dowex Resin: A Unique Microvessel and Heterogeneous Catalyst in Nucleophilic Substitution Reactions.
Authors: Kiasat Ali Reza , Zarinderakht Nasrollah , Sayyahi Soheil 
Published: August 2012

AbstractThe reaction is conducted under environmentally benign conditions.
ChemInform Abstract: NaOH—Al2O3 Catalyzed Synthesis of 1,3,5‐Triarylpentane‐1,5‐diones Derivatives under Solvent‐Free Condition and Crystal Structure of 3‐(2′,4′‐Dichlorophenyl)‐1,5‐diphenylpentane‐1,5‐dione.
Authors: Huang Xianqiang , Feng Qiu , Sun Yanliang , He Qingpeng , Wang Yong 
Published: August 2012

AbstractAn efficient, mild and fast procedure for the preparation of title series (III) is reported.
ChemInform Abstract: Asymmetric Michael Addition of N‐Boc‐Protected Oxindoles to Nitroalkenes Catalyzed by a Chiral Secondary Amine.
Authors: Wang Chuan , Yang Xuena , Enders Dieter 
Published: August 2012

AbstractAmong 14 prolinol ethers tested in the reaction of oxindole (Ig) with nitrostyrene, didodecylprolinol Tms‐ether PRO affords the best result with respect to both yield and diastereo‐ and enantioselectivity of the addition product.
ChemInform Abstract: Copper‐Catalyzed Aerobic Methyl/Methylene Oxygenation and C—H Formylation with a DABCO—DMSO System for the Synthesis of Carbonyl Indoles and Pyrroles.
Authors: Wang Yi‐Feng , Zhang Feng‐Lian , Chiba Shunsuke 
Published: August 2012

AbstractThe conditions which are used for the aerobic oxidation process can also be applied to the direct C‐3 formylation.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition Reactions of 2‐Substituted Azomethine N‐Oxides with N‐Benzyl Maleimides Leading to the Synthesis of Stereoisomers.
Authors: Badru Rahul , Shah Sakshi , Singh Baldev 
Published: August 2012

AbstractAzomethine N‐oxides (I) and (V) react with N‐benzylmaleimide (II) to provide a mixture of stereoisomers having cis (III), (VII) and trans (IV), (VI) configurations with respect to the proton on the C‐3 azomethine carbon.
ChemInform Abstract: An Easy Access to 4,5‐Disubstituted Thiazoles via Base‐Induced Click Reaction of Active Methylene Isocyanides with Methyl Dithiocarboxylates.
Authors: Lingaraju Gejjalagere S. , Swaroop Toreshettahally R. , Vinayaka Ajjampura C. , Kumar Kothanahally S. Sharath , Sadashiva Marilinganadoddi P. , Rangappa Kanchugarakoppal S. 
Published: August 2012

AbstractThe method allows a simple and rapid approach to the title compounds (23 examples).
ChemInform Abstract: Cu‐Catalyzed Three‐Component Synthesis of Substituted Benzothiazoles in Water.
Authors: Deng Hang , Li Zhengkai , Ke Fang , Zhou Xiangge 
Published: August 2012

AbstractIn the presence of an optimized catalyst system, the reaction of iodoanilines, aromatic, heteroaromatic or aliphatic aldehydes, and an excess of sulfur affords the corresponding 2‐substituted benzothiazoles.
ChemInform Abstract: Synthesis of 1‐{4a,6‐Dimethyl‐4a,9a‐dihydropyrano[3,4‐b]indol‐9(1H)‐yl}ethanone (VI).
Authors: Skladchikov D. A. , Fatykhov A. A. , Gataullin R. R. 
Published: August 2012

Abstractby copper/palladium‐catalyzed heterocyclization of amide (V)
ChemInform Abstract: Tetrakis(acetonitrile)copper(I) Hexafluorophosphate Catalyzed Coumarin Synthesis via Pechmann Condensation under Solvent‐Free Condition.
Authors: Soleimani Ebrahim , Khodaei Mohammad Mehdi , Batooie Nasim , Samadi Saadi 
Published: August 2012

AbstractPechmann condensation of phenols with β‐ketoesters under mild conditions leads to formation of coumarin derivatives in excellent yields.
ChemInform Abstract: Tetrahydroquinazoline‐Substituted Chromones from Diels—Alder Reaction of (E)‐2‐Styrylchromones and Pyrimidine ortho‐Quinodimethane.
Authors: Patoilo Diana T. , Silva Artur M. S. , Pinto Diana C. G. A. , Santos Clementian M. M. , Tome Augusto C. , Cavaleiro Jose A. S. 
Published: August 2012

AbstractThe reaction produces 2 regioisomers, where the trans configuration of the starting material remains intact.
ChemInform Abstract: Synthesis and Light‐Stabilizing Ability of a Series of Hindered Piperidine Derivatives.
Authors: Chen Wei , An Ping , Chen Yan‐Xue , Li Yang , Yan Xi‐Long , Chen Li‐Gong 
Published: August 2012

AbstractThe oxidation resistance and photostabilization efficiency of title compounds (Ia) and (Ib) is better than that of HALS tinuvin 770, chimassorb 944, tinuvin 622 and irganox B215.
ChemInform Abstract: One‐Pot Synthesis of 4‐Substituted Isoquinolinium Zwitterionic Salts by Metal‐Free C—H Bond Activation.
Authors: Hou Hong , Zhang Yuan , Yan Chao‐Guo 
Published: August 2012

AbstractThe synthesis of 25 examples of the title series via a multicomponent reaction of in situ formed N‐benzylisoquinolinium bromides with aromatic aldehydes and cyclic 1,3‐dicarbonyl compounds is presented.
ChemInform Abstract: Polycyclic N‐Heterocyclic Compounds. Part 69. Synthesis of 5‐Amino‐1,2‐dihydro[1]benzofuro[3,2‐d]furo[2,3‐b]pyridines and Their Transformations to Related Compounds.
Authors: Okuda Kensuke , Takano Jun‐ichi , Hirota Takashi , Sasaki Kenji 
Published: August 2012

AbstractRing closure reaction of 1,6‐dinitriles (I) in the presence of strong base proceeds via Thorpe—Ziegler pathway to give oxepine derivatives (II), and via Truce—Smiles rearrangement to give difuropyridines (III).
ChemInform Abstract: Phosphine‐Catalyzed [3 + 2] and [4 + 3] Annulation Reactions of C,N‐Cyclic Azomethine Imines with Allenoates.
Authors: Jing Chengfeng , Na Risong , Wang Bo , Liu Honglei , Zhang Lei , Liu Jun , Wang Min , Zhong Jiangchun , Kwon Ohyun , Guo Hongchao 
Published: August 2012

AbstractThe reaction pathways can be triggered by choice of the allenoate and the phosphine catalyst.
ChemInform Abstract: Thiourea Dioxide in Water as a Recyclable Catalyst for the Synthesis of Structurally Diverse Dihydropyrido[2,3‐d]pyrimidine‐2,4‐diones.
Authors: Verma Sanny , Jain Suman L. 
Published: August 2012

AbstractA convenient protocol is developed for the synthesis of the biologically important scaffolds (IV) via three‐component reaction.
ChemInform Abstract: Microwave‐Assisted Domino Benzannulation of α‐Oxo Ketenes: Preparation of 1,3‐Dihydro‐2H‐1,5‐benzodiazepin‐2‐ones.
Authors: Castillo Juan‐Carlos , Presset Marc , Abonia Rodrigo , Coquerel Yoann , Rodriguez Jean 
Published: August 2012

AbstractThe title reaction of 2‐diazo‐1,3‐diones and o‐phenylenediamines in the absence of any additive affords bi‐ or tricyclic benzodiazepinones by a domino Wolff rearrangement/nucleophilic addition/intramolecular imination sequence with the formation of three new covalent bonds.
ChemInform Abstract: Small Organophosphorus—Selenium Heterocycles from the Selenation of Conjugated Ketones and Enals.
Authors: Hua Guoxiong , Slawin Alexandra M. Z. , Woollins J. Derek 
Published: August 2012

Abstractα,β‐Unsaturated ketones and aldehydes react with Woollins′ reagent (II) to give novel five‐membered heterocycles as diasteromeric and isomeric mixtures.
ChemInform Abstract: Enantiodivergent Chemoenzymatic Synthesis of (S)‐ and (R)‐(Z)‐9‐Dodecyl‐4,5,8,9‐tetrahydro‐3H‐oxonin‐2‐one as Analogues of Topsentolides.
Authors: Wetzel Isolde , Krauss Juergen , Bracher Franz 
Published: August 2012

AbstractKey steps in the new approach to enantiopure title compounds (IV) are a kinetic enzymatic resolution of racemic alcohol (I) and the Grubbs I catalyzed stereoselective ring‐closing metathesis to the desired (Z)‐lactones.
ChemInform Abstract: Synthesis of Bismuth Pseudocubes by Thermal Decomposition of Bi2Et4.
Authors: Schulz Stephan , Heimann Stefan , Woelper Christoph , Assenmacher Wilfried 
Published: August 2012

AbstractHighly crystalline, nearly monodisperse 25 nm sized bismuth pseudocubes are prepared by a low temperature thermolysis reaction of Bi2Et4 in the presence of Na[N(SiMe3)2] and poly(1‐vinylpyrolidone)‐graft‐(1‐triacontene) (50 °C, 4 h).
ChemInform Abstract: Pictet—Spengler Reaction Revisited: Engineering of Tethered Biheterocycles into Annulated Polyheterocycles
Authors: Kundu Bijoy , Agarwal Piyush K. , Sharma Sudhir K. , Sawant Devesh , Mandadapu Anil K. , Saifuddin Mohammad , Gupta Sahaj 
Published: August 2012

AbstractReview: 123 refs.
Magic truffles or Philosopher's stones: a legal way to sell psilocybin?
Authors: Pellegrini Manuela , Rotolo Maria Concetta , Marchei Emilia , Pacifici Roberta , Saggio Francesco , Pichini Simona 
Published: August 2012

“Magic mushrooms” is the most common name given to hallucinogenic fungi containing the psychoactive alkaloids psilocybin and psilocin. In recent years, fungis' sclerotia, commonly called “magic truffles” have become a form of supply of psychoactive Psilocybe alkaloids since Psilocybe sclerotia are not specifically included in the laws banning the sale, the purchase and the use of such substances and mushrooms containing them.A liquid chromatography –tandem mass spectrometry (LC‐MS/MS) method was developed for the rapid determination of psilocybin and psilocin in Psilocybe sclerotia. Following a simple step extraction with methanol, the alkaloids were separated on a reversed‐phase column using a gradient of 0.1% formic acid – acetonitrile s a mobile phase at a flow rate of 0.2 mL/min.. Separated analytes were detected by electrospray ionization tandem mass spectrometry in the positive ion mode using multiple reaction monitoring. The developed method was linear over the calibration range for all two substances under investigation, with a r2 > 0.99. The detection and quantification limits were 0.3 µg and 1 µg per 100 mg truffles, for both psilocin and psilocybin and the intra‐ and inter‐day coefficients of variation were always better than 15%.Using this method, the presence of only psilocybin was demonstrated in examined Psilocybe sclerotia. The content of psilocybin was found to vary over a concentration range of 59.3 to 167.8 µg per 100 mg of fresh sclerotia. Copyright © 2012 John Wiley & Sons, Ltd.
Temperature alters reproductive life history patterns in Batrachochytrium dendrobatidis, a lethal pathogen associated with the global loss of amphibians
Authors: Voyles Jamie , Johnson Leah R. , Briggs Cheryl J. , Cashins Scott D. , Alford Ross A. , Berger Lee , Skerratt Lee F. , Speare Rick , Rosenblum Erica Bree 
Published: August 2012

AbstractUnderstanding how pathogens respond to changing environmental conditions is a central challenge in disease ecology. The environmentally sensitive fungal pathogen Batrachochytrium dendrobatidis (Bd), which causes the amphibian disease chytridiomycosis, has spread globally causing amphibian extirpations in a wide variety of climatic regions. To gain an in‐depth understanding of Bd's responses to temperature, we used an integrative approach, combining empirical laboratory experiments with mathematical modeling. First, we selected a single Bd isolate and serially propagated two lineages of the isolate for multiple generations in two stable thermal conditions: 4°C (cold‐adapted lineage) and 23°C (warm‐adapted lineage). We quantified the production of infectious zoospores (fecundity), the timing of zoospore release, and zoospore activity in reciprocal temperature transplant experiments in which both Bd lineages were grown in either high or low temperature conditions. We then developed population growth models for the Bd lineages under each set of temperature conditions. We found that Bd had lower population growth rates, but longer periods of zoospore activity in the low temperature treatment (4°C) compared to the high temperature treatment (23°C). This effect was more pronounced in Bd lineages that were propagated in the low temperature treatment (4°C), suggesting a shift in Bd's response to low temperature conditions. Our results provide novel insights into the mechanisms by which Bd can thrive in a wide variety of temperature conditions, potentially altering the dynamics of chytridiomycosis and thus, the propensity for Bd to cause amphibian population collapse. We also suggest that the adaptive responses of Bd to thermal conditions warrant further investigation, especially in the face of global climate change.