bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fluviomorphic trajectories for dryland ephemeral stream channels following extreme flash floods
Authors: Lotsari Eliisa , House P. Kyle , Alho Petteri , Baker Victor R. 
Published: May 2024

AbstractEphemeral alluvial streams pose globally significant flood hazards to human habitation in drylands, but sparse data for these regions limit understanding of the character and impacts of extreme flooding. In this study, we document decadal changes in dryland ephemeral channel patterns at two sites in the lower Colorado River Basin (southwestern United States) that were ravaged by extraordinary flash floods in the 1970s: Bronco Creek, Arizona (1971), and Eldorado Canyon, Nevada (1974). We refer to these two floods as ‘fluviomorphic erasure events’, because they produced blank slates for the channels that were gradually moulded by more frequent but much smaller flood events. We studied georectified aerial photos that span ~60 years at each site to show that both study sites recovered to their pre‐flood condition after ~25 years. We employ channel network metrics: stream‐link area (SLA), geometric braiding index and junction‐node density. Each metric decreased during the short‐duration extreme flood erasure events. Subsequently, a fluviomorphic trajectory at a decadal tempo returned the channels to pre‐flood values. The SLA decreased at rates of 3.6%–4.1% per year in the decade following the floods. The extreme flood events decreased the pre‐flood geometric braiding index at the two sites by 56%–68%, and it took 15–24 years for this index to recover to pre‐flood values. In contrast, it took 30–35 years for the channels to recover to a uniform pre‐flood channel form, as indicated by the spatial distribution of bars and junction nodes. Our results document baseline examples of ephemeral stream channel evolution trajectories, as future climatic change will likely accelerate increases in the magnitudes and frequencies of extreme floods and geomorphic erasure events.
Mechanism of rainfall‐induced toppling in loess collapses
Authors: Hou Tian‐shun , Jiang Xiao‐dong , Chen Ye 
Published: May 2024

AbstractTo study the formation mechanism of rainfall‐induced soil erosion, collapse and landslides in the Loess Plateau based on the unsaturated soil seepage theory and the effective stress principle, the failure process of collapse with cracks under heavy and long‐term rainfall was investigated using the finite element method. The results showed that under the action of heavy rain, surface run‐off quickly gathered in cracks to form a dominant flow, resulting in a rapid increase in the water level and hydrostatic pressure in the cracks. The strength of the soil at the tip of the crack decreased rapidly under the softening effect of the water, and tensile failure occurred. The crack accelerated downward to the foot of the slope, causing the steep slope to collapse. Long‐term rainfall acts directly on the soil near the crack, resulting in faster saturation than the soil inside the slope body. When the rainfall time exceeded a certain value, the soil near the crack reached a saturated state, and the soil strength was minimized. Simultaneously, the seepage force generated when rainwater inside the collapsed body seeps from its outer edge increases the overturning moment of the collapsed body. Under the continuous action of rainfall, the cracks gradually extended to the foot of the slope, causing the collapsed body to fail. These research results provide a theoretical basis for the prevention and control of land degradation and collapse disasters on the Loess Plateau.
A comprehensive review on nutritional interventions and nutritive elements: Strengthening immunity for effective defense mechanism during pandemic
Authors: Prasad Sonal , Pandey Vinay Kumar , Singh Kunal , Shams Rafeeya , Singh Rahul , Goksen Gulden 
Published: May 2024

AbstractThe pandemic has brought attention to the importance of a healthy immune system in preventing infectious diseases. In this in‐depth review, the process by which nutritional interventions and fundamental nutrients affect immune function has been discussed with the goal of enhancing the body's natural defenses against viral infections. We explored the complex interplay between diet and immunology, highlighting the essential nutrients, vitamins, minerals, and bioactive substances that are crucial for enhancing immune response. We also investigated the effect of dietary patterns and supplementation methods on immune function. We assessed the effectiveness and potential mechanisms of action of various nutritional therapies in modifying immune responses through a thorough examination of scientific literature. Additionally, we go through the significance of individualized nutrition and highlight possible factors to consider for vulnerable groups, such as the elderly and people with chronic conditions. This review attempts to provide a thorough understanding of the role of diet in boosting immunity by synthesizing available research. It also offers insights into practical methods for enhancing the immune function during the current epidemic and in the future.
Associations between low‐ and high‐fat dairy intake and recurrence risk in people with stage I–III colorectal cancer differ by sex and primary tumour location
Authors: van Lanen Anne‐Sophie , Kok Dieuwertje E. , Wesselink Evertine , Derksen Jeroen W. G. , May Anne M. , Smit Karel C. , Koopman Miriam , de Wilt Johannes , Kampman Ellen , van Duijnhoven Fränzel J. B. ,   the COLON and PLCRC studies
Published: May 2024

AbstractWe previously demonstrated that intake of low‐fat dairy, but not high‐fat dairy, was associated with a decreased colorectal cancer (CRC) recurrence risk. These risks, however, may differ by sex, primary tumour location, and disease stage. Combining data from two similar prospective cohort studies of people with stage I–III CRC enabled these subgroup analyses. Participants completed a food frequency questionnaire at diagnosis (n = 2283). We examined associations between low‐ and high‐fat dairy intake and recurrence risk using multivariable Cox proportional hazard models, stratified by sex, and primary tumour location (colon and rectum), and disease stage (I/II and III). Upper quartiles were compared to lower quartiles of intake, and recurrence was defined as a locoregional recurrence and/or metastasis. During a median follow‐up of 5.0 years, 331 recurrences were detected. A higher intake of low‐fat dairy was associated with a reduced risk of recurrence (hazard ratio [HR]: 0.60, 95% confidence interval [CI]: 0.43–0.83), which seemed more pronounced in men (HR: 0.51, 95% CI: 0.34–0.77) than in women (HR: 0.84, 95% CI: 0.47–1.49). A higher intake of high‐fat dairy was associated with an increased risk of recurrence in participants with colon cancer (HR: 1.60, 95% CI: 1.03–2.50), but not rectal cancer (HR: 0.88, 95% CI: 0.54–1.45). No differences in associations were observed between strata of disease stage. Concluding, our findings imply that dietary advice regarding low‐fat dairy intake may be especially important for men with CRC, and that dietary advice regarding high‐fat dairy intake may be specifically important in people with colon cancer.
Managing weaning issues in lambs and ewes. Part 2: management of ewes following weaning
Authors: Forster Rachel , Falder Nicola 
Published: May 2024

Background: To ensure optimum flock fertility in the subsequent breeding season, it is important to ensure that ewes are in good health following weaning. Drafting (the period between weaning and tupping where ewes are sorted for culling) is a key time in the flock year to ensure only the most productive ewes are retained for breeding. Identifying health issues soon after weaning allows time for recovery, or for replacements to be sourced if necessary. Postweaning is also often an important time for the identification of underlying endemic diseases within a flock – the stress of pregnancy and lactation may exacerbate clinical signs and guide the clinician towards the requirement for diagnostic investigations.Aim of the article: This article, the second in a two‐part series on managing weaning issues in lambs and ewes, provides information about common health conditions that can be identified in the postweaning period which could affect subsequent reproductive performance of ewes. Examination of culling data of ewes can provide practitioners with information about the health of the flock and potential underlying health conditions to investigate. Information regarding how to investigate these conditions is also presented. Part one of this series, which was published in the January/February issue of In Practice (Forster and Falder 2024), focused on the common issues encountered by both ewes and lambs at weaning time and how to minimise these problems.
Treatment considerations for bluetongue virus serotype‐3 cases in sheep
Authors: Lovatt Fiona , Tarlinton Rachael , Groenevelt Margit 
Published: May 2024

Background: Bluetongue virus (BTV) serotype‐3 (BTV‐3) has been circulating in the Netherlands since September 2023 and was first reported in Kent in the UK in November 2023, picked up via the annual bluetongue surveillance programme. It is a highly pathogenic strain in sheep with limited preventive measures once virus is circulating in the biting midge population. At the time of publication there is no BTV‐3 vaccine available and no cross‐protection from other BTV vaccine strains. There are no specific antiviral medicines available, and therapy focuses on nursing care and anti‐inflammatory medicines to reduce clinical signs, although early euthanasia decisions need to be considered on the grounds of animal welfare.Aim of the article: This article takes the experiences of vets from the Netherlands and describes what practitioners might be able to do to treat clinical cases of BTV‐3, with thanks to Schapendokter (2023) for sharing their practice protocols.
Evaluation and projection of circulation conditions tied to summertime compound drought and heatwave frequency over the Yangtze River Delta, China, for the carbon neutrality period based on CMIP6 GCMs
Authors: Wang Jing , Liang Ping , Cheng Fei , Liu Yanju , Song Chengyu , Wu Wei , Zheng Qingfeng , Zhang Tianyu , Qu Ping , Li Yujie , Ding Yihui 
Published: May 2024

AbstractFrequent occurrences of compound droughts and heatwaves (CDHWs) may have considerable adverse impacts on human health and socioeconomic development. To project future summertime CDHWs over the Yangtze River Delta (YRD) of China under carbon neutrality (CN) for policymakers, we used nine global climate models (GCMs) from the Coupled Model Intercomparison Project Phase 6 (CMIP6) and evaluated and projected circulation conditions tied to the summer YRD CDHW frequency in the boreal summer. The results show that a marked mid‐tropospheric regional‐scale anticyclonic anomaly centred over the East China Sea can be deemed the dominant system linking the more frequent occurrence of YRD CDHWs. Our selected nine CMIP6 GCMs better captured the observed climatological and anomalous spatial circulation patterns connected to the summer YRD CDHW frequency. Moreover, the nine models' multi‐model ensemble mean (9MME) was better than most of the individual models regarding the related climatological circulation simulations. The 9MME‐projected changes in circulation conditions tied to summer YRD CDHWs during the carbon neutrality period (2050–2060) under SSP119 favour the comparable occurrence of the YRD with that for the same period under the medium greenhouse gas (GHG) warming scenario (SSP245), but the intensities of the CDHWs are the least severe. However, the highest number of YRD CDHWs is driven by the high GHG warming scenario (SSP585), and these CDHWs feature the most severe intensity. Our research identified a new paradigm regarding the frequency and intensity of the summer YRD CDHW under SSP119, highlighting the potential role of the newly accessible CN‐oriented sustainable development pathway in alleviating compound extremes.
Hyperkinetic Movement Disorder Caused by the Recurrent c.892C>T NACC1 Variant
Authors: Komulainen‐Ebrahim Jonna , Kangas Salla M. , López‐Martín Estrella , Feyma Timothy , Scaglia Fernando , Martínez‐Delgado Beatriz , Kuismin Outi , Suo‐Palosaari Maria , Carr Lucinda , Hinttala Reetta , Kurian Manju A. , Uusimaa Johanna 
Published: May 2024

AbstractBackgroundGenetic syndromes of hyperkinetic movement disorders associated with epileptic encephalopathy and intellectual disability are becoming increasingly recognized. Recently, a de novo heterozygous NACC1 (nucleus accumbens‐associated 1) missense variant was described in a patient cohort including one patient with a combined mitochondrial oxidative phosphorylation (OXPHOS) deficiency.ObjectivesThe objective is to characterize the movement disorder in affected patients with the recurrent c.892C>T NACC1 variant and study the NACC1 protein and mitochondrial function at the cellular level.MethodsThe movement disorder was analyzed on four patients with the NACC1 c.892C>T (p.Arg298Trp) variant. Studies on NACC1 protein and mitochondrial function were performed on patient‐derived fibroblasts.ResultsAll patients had a generalized hyperkinetic movement disorder with chorea and dystonia, which occurred cyclically and during sleep. Complex I was found altered, whereas the other OXPHOS enzymes and the mitochondria network seemed intact in one patient.ConclusionsThe movement disorder is a prominent feature of NACC1‐related disease.
Updated‐generation product introduction decisions under trade‐in programs and different pricing strategies
Authors: Fan Xiaojun , Zhao Wenyu , Zhu Xiaowei 
Published: May 2024

AbstractManufacturers introduce updated‐generation products to meet intensified competition under trade‐in programs. Based on this phenomenon, we built a two‐period game‐theoretic model, in which the manufacturer sells the old‐generation product during both periods and considers whether to introduce the updated‐generation product in the second period. We find that under a static pricing strategy, if the costs of both products are low, the updated‐generation product's entry increases the old‐generation product's retail price. The manufacturer cannot benefit from introducing the updated‐generation product if the updated‐generation product's cost is high. Under a dynamic pricing strategy, the updated‐generation product entry benefits both the manufacturer and the consumer.
Predictive value of adductor pollicis muscle thickness for ultrasound‐based sarcopenia in older adults
Authors: Varan Hacer D. , Ceker Eda , Cataltepe Esra , Gungor Fatih , Fadiloglu Ayse , Borazan Funda Y. 
Published: May 2024

AbstractBackgroundThe adductor pollicis muscle thickness (APMT) is least affected by subcutaneous adipose tissue and can be measured externally. The aim of this study is to identify the predictive value of APMT for the diagnosis of ultrasonography‐based sarcopenia.MethodsA total of 245 outpatients who were aged ≥65 years (49 with sarcopenia and 196 without sarcopenia) were included in this cross‐sectional study. Patients with knee or hip replacement, advanced dementia, cerebrovascular disease, neurodegenerative disease, or decompensated heart failure and those using drugs that affect muscle functions, such as steroids, were excluded. Comprehensive geriatric assessments and anthropometric measurements of the patients were performed. APMT was assessed with a skinfold caliper. The diagnosis of sarcopenia was based on a low Sonographic Thigh Adjustment Ratio (STAR) index (anterior thigh muscle thickness by ultrasonography/body mass index [BMI] ratio, cutoff points are <1.4 for men and <1.0 for women) and low handgrip strength. The predictive ability of APMT for ultrasound‐based sarcopenia diagnosis was examined.ResultsThere was no significant difference in terms of arm and calf circumference and BMI between the sarcopenic and nonsarcopenic groups. APMT, handgrip strength, anterior thigh muscle thickness, and gait speed were significantly lower in the patients with sarcopenia. The best cutoff points of APMT for sarcopenia were ≤16.5 for women and ≤21.5 for men with areas under the curve of 0.70 and 0.66, respectively, and negative predictive values of 91.2 and 94.3, respectively (P < 0.001).ConclusionAPMT can be a useful anthropometric marker for ultrasound‐based sarcopenia diagnosis.
Celebrity and influencer philanthropy: Debating MrBeast and China
Authors: Jeffreys Elaine , Xu Jian 
Published: May 2024

AbstractThis article examines the philanthropy/marketing interface with reference to celebrity philanthropy, focusing on the American YouTube star, MrBeast, and the Chinese government regulation of celebrities and social media influencers. Celebrity nowadays can refer to film and music stars with international broadcast media visibility and to people who create their own fame through social media and appeals to niche markets/audiences (social media influencers). While the United States of America has historically used tax incentives to encourage elite philanthropy as a matter of individual choice, the Chinese government is regulating the cultural industries to promote and direct celebrity and influencer philanthropy towards government‐endorsed development goals. Comparing debates about MrBeast philanthropy with the operation of philanthropy in China highlights different ideas about celebrity/influencer philanthropy and the role it can play in supporting public welfare.
Optimal control of stochastic differential equations with random impulses and the Hamilton–Jacobi–Bellman equation
Authors: Yin Qian‐Bao , Shu Xiao‐Bao , Guo Yu , Wang Zi‐Yu 
Published: May 2024

AbstractIn this article, we study the optimal control of stochastic differential equations with random impulses. We optimize the performance index and add the influence of random impulses to the performance index with a random compensation function. Using the idea of stochastic analysis and dynamic programming principle, a new Hamilton–Jacobi–Bellman (HJB) equation is obtained, and the existence and uniqueness of its viscosity solution are proved.
Comparative study of sample preparation procedures to determine the main compounds in ayahuasca beverages by QuEChERS and high‐performance liquid chromatography analysis
Authors: Gonçalves Joana , Rosado Tiago , Barroso Mário , Restolho José , Fernández Nicolás , Luís Ângelo , Gallardo Eugenia , Duarte Ana Paula 
Published: May 2024

AbstractIntroductionAyahuasca is a psychoactive drink originally consumed by indigenous people of the Amazon. The lack of regulation of this drink leads to uncontrolled consumption, and it is often consumed in religious contexts.ObjectiveThe aim of this work is to compare three miniaturised extraction techniques for extracting the main ayahuasca compounds from beverages.MethodologyThree sample pretreatment techniques were evaluated (dispersive liquid–liquid microextraction [DLLME], microextraction by packed sorbent [MEPS] and QuEChERS [Quick, Easy, Cheap, Effective, Rugged and Safe]) for the simultaneous extraction of N,N‐dimethyltryptamine (DMT), tetrahydroharmine (THH), harmine, harmaline, harmol and harmalol from ayahuasca beverage samples. Then, the most promising technique (QuEChERS) was chosen to pre‐concentrate the analytes, subsequently detected by high‐performance liquid chromatography coupled to a diode array detector (HPLC‐DAD).ResultsThe procedure was optimised, with the final conditions being 500 μL of extractor solvent, 85 mg of primary secondary amine (PSA) and 4 s of vortexing. The analytical method was validated, showing to be linear between 0.16 and 10 μg/mL for β‐carbolines and between 0.016 and 1 μg/mL for DMT, with coefficients of determination (R2) between 0.9968 and 0.9993. The limit of detection (LOD) and lower limit of quantification (LLOQ) were 0.16 μg/mL for all compounds, except for DMT (0.016 μg/mL) and extraction efficiencies varied between 60.2% and 88.0%.ConclusionThe analytical methodology proved to be accurate and precise, with good linearity, LODs and LLOQs. This method has been fully validated and successfully applied to ayahuasca beverage samples.
Development of HDPE/natural fiberboard nanocomposite reinforced Bi2O3/BaO and H3BO3: A sustainable approach for gamma and neutron shielding application
Authors: Yassene Ali A. M. , Abd Elwahab Nesreen R. , Eyssa Hanan M. 
Published: May 2024

AbstractRadiation shielding materials significantly contribute to various fields. In this research, a new eco‐friendly nanocomposite shielding material based on high‐density polyethylene (HDPE) and natural fiberboard (NF) with different concentrations of barium oxide nanowires (BaO), bismuth oxide nanorods (Bi2O3), and boric acid (H3BO3) is constructed and investigated for 137Cs, 60Co gamma ray, and 142Am–Be neutron sources. Mechanical and physical testing and thermal analysis were conducted to assess the impact of nanostructure incorporation on the structural integrity and thermal stability of the nanocomposite. The 60Co gamma and neutron attenuation properties were evaluated using the appropriate radiation sources. The transmission and absorption coefficients of the nanocomposites were measured. The results demonstrated that HDPE/NF filled with BaO, Bi2O3 nanostructure, and boric acid has higher tensile strength and thermal stability than unfilled HDPE/NF. The results displayed that the HDPE/NF filled with 1.5% Bi2O3 and 1.5% BaO improved gamma attenuation and also HDPE/NF/10% boric acid had a high value. The outcomes of this research provide valuable insights into the design and fabrication of radiation shielding materials by understanding the relationship between nanoparticle concentration, radiation attenuation properties, and the mechanical and thermal characteristics of the nanocomposite. This study aims to optimize the performance and applicability of HDPE/NF nanocomposites for radiation protection applications.Highlights
Synthesis of BaO nanowires and bismuth oxide (Bi2O3) nanorods by hydrothermal simple method.
Fabrication and characterization of a new HDPE/natural fiberboard (NF) nanocomposite containing BaO/Bi2O3/H3BO3 as an eco‐friendly additive.
The HDPE/NF/1.5% BaO/1.5% Bi2O3 nanocomposite has better tensile strength and more thermal stability.
Usage of HDPE/NF/1.5% BaO/1.5% Bi2O3 nanocomposite that should be utilized for radiation shielding.
Usage of HDPE/NF/1.5% BaO/1.5% Bi2O3/10% H3BO3 nanocomposite that should be utilized for neutron attenuation performance.