bluuebunny/crossref_metadata_2025_split huggingface dataset:
O PAPEL DO FARMACÊUTICO NA ONCOLOGIA: UMA REVISÃO INTEGRATIVA
Authors: Vieira Manuela Fonseca , Pereira Emanoela Pessoa , Juvêncio Beatriz Alves , Capibaribe Victor Celso Cavalcanti , Costa Flavio Nogueira da , Lopes Nadja Mara de Sousa 
Published: May 2024

Introdução: O câncer é um grave problema de saúde em todas as populações, independentemente do status social. O crescimento na incidência de câncer e nos gastos para seu controle acentua sua importância como problema de saúde pública no país, desafiando gestores em saúde. A terapêutica do paciente oncológico requer diversos tratamentos combinados, sendo essencial que seja realizado trabalho de forma individualizada, atendendo assim suas necessidades. Nesse contexto, é de grande importância a existência de uma equipe multidisciplinar no acompanhamento do paciente durante todo o tratamento. Metodologia: Este trabalho trata-se de uma revisão integrativa. A pesquisa nas fontes de busca foi dividida em duas etapas, a primeira no portal eletrônico da SOBRAFO, onde foi buscado legislações que envolvem o papel do farmacêutico oncológico; a segunda etapa consistiu na pesquisa de artigos nas bases de dados e ferramentas de pesquisa como: Google Acadêmico, LILACS e IBECS. Resultado: A busca no portal eletrônico da SOBRAFO devolveu 10 legislações, sendo quatro da ANVISA, quatro do CFF e duas do MS. Já na busca de artigos, foram encontradas seis publicações referentes ao tema, todas vinculadas ao contexto nacional, já que leis e regulamentações nacionais foram usadas para confecção do trabalho. Discussão: Ficou claro que as atividades exercidas pelo farmacêutico evidenciam seu papel na oncologia. Segundo os artigos, são citados os seguintes papéis: análise das prescrições médicas; participação na equipe multiprofissional de assistência ao paciente; atenção farmacêutica; farmácia clínica; farmacovigilância; cuidados paliativos e manipulação de agentes citostáticos. Conclusão: A participação ativa do farmacêutico na oncologia se faz necessária, já que ele age contribuindo para uma terapia segura, proporcionando baixos índices de reações aos medicamentos e/ou problemas relacionados aos medicamentos. Consequentemente, agindo de forma direta na segurança do paciente.
PENGARUH GAYA KEPEMIMPINAN TERHADAP KINERJA KARYAWAN DI HOTEL CANGGU DREAM VILLAGE
Authors: Manika Dewi Anak Agung Candra , Sihombing Irene Hanna H. , Pratiwi Kadek Andita Dwi 
Published: May 2024

Pentingnya keberadaan sumber daya manusia dalam pengembangan usaha jasa pariwisata terlihat dari kemampuan suatu perusahaan untuk berkembang sangat bergantung pada kemampuan kinerja karyawan untuk melaksanakan tugas – tugas kerja yang terarah untuk pengembangan perusahaan. Tujuan penelitian ini adalah untuk menganalisis pengaruh pengaruh gaya kepemimpinan terhadap kinerja karyawan di Hotel Canggu Dream Village. Jumlah sampel yang digunakan sebanyak 45 orang menggunakan metode sampel jenuh. Pengumpulan data menggunakan kuesioner berskala likert. Teknik analisa data menggunakan analisis regresi linear sederhana. Uji hipotesis dilakukan menggunakan uji-t. Hasil penelitian menunjukkan variabel gaya kepemimpinan demokratis yaitu 6,626 dibandingkan t tabel yaitu 1,6 yang artinya menolak H0 atau H1 diterima karena t-hitung > t-tabel = 6,626 > 1,6 artinya gaya kepemimpinan demokratis berpengaruh positif signifikan terhadap kinerja karyawan di Hotel Canggu Dream Village, dengan demikian dapat dimaknai bahwa semakin baik penerapan gaya kepemimpinan demokratis maka kinerja karyawan semakin tinggi. Besarnya pengaruh gaya kepemimpinan demokratis terhadap kinerja karyawan sebesar 49,4%. Diharapkan pimpinan menyediakan waktu atau kesempatan kepada bawahan untuk menyampaikan masukan dari bawahan.
GC-MS, Chemical Characterization and Anti-Microbial Activity of Moringa Oleifera Leaf Extract
Authors: A. N. Madu, , C. I. Iwu, , E. E. Joseph, , K. N. Maduako, , J. N. Madu, , E. I. Mbakwe, 
Published: May 2024

The analysis of the leaf of Moringa oleifera was carried out using Gas Chromatography Mass Spectroscopy (GC-MS). Result obtained showed the presence of alkaloids, flavonoids, steroids, tannins, terpenoids and cardiac glycoside. The GC-MS analysis showed that the leaf extract contained 16 compounds which included; Dodecanoic acid (C12H24O2), Tetradecanoic acid, (C14H2802), Hexadecanoic acid, (C17H34O2), n-Hexadecanoic acid, (C16H3202), 9-Octadecanoic acid (C19H36O2), cis-Vaccinic acid, (C18H34O2), Oleic acid, (C18H34O2), Eicosanoic acid, (C21H42O2), Oleic acid, 3-hydroxylpropyl ester (C21H40O3), Oleic acid, (C18H34O2), Docosanoic acid, Methyl ester, (C23H46O2), Vitamin E (C29H50O2), Trioxa-5-phosphaheptacos-18-en-1-aminium,4-hydroxyl-N,N,N-trimethyl-10-oxo-{(1-oxo-9-ocl)}, (C44H84NO8P), Oleic acid, 3-(octadecyloxy) propyl ester, (C39H76O3), Oleic acid, 3-(octadecyloxy) propyl ester, (C39H76O3), 9-Octadecanoicacid [Z]., 2-hydroxyl-1,3-propanedyl ester, (C39H72O5).	Similarly, the antimicrobial result showed that the extract had activities against six selected human pathogens such as; Staphylococcus aureus with diameter of inhibition 3.8 and minimum inhibition concentration (MIC) of 50 mg/g, Streptococcus spp with diameter of inhibition 5 and (MIC) 25mg/g, Escherichia coli with diameter of inhibition 20 and (MIC) of 25mg/g, Salmonela. typhi with diameter of inhibition 3 and (MIC) 50, P. aureginosa with diameter of inhibition 3 and (MIC) 50.
Development of Water Level Controller with SMS Capability
Authors: Adesina Lambe Mutalub , Ogunbiyi Olalekan , Jimada-Ojuolape Bilkisu 
Published: May 2024

Water is considered a valuable resource and covers about 70% of the earth's surface. Tight schedule prevents regular checking of the domestic water tank level while refilling the used ones. This often leads to waste of water and increased monthly revenue payment to power utility company. Consequently, this paper presents a development of water level controller with SMS capability aimed at measuring water level smartly such that when tank is filled, message would be automatically transmitted as an alert to the owner using GSM for immediate response. The method involves interconnection of a water container that serves as tank with another open container serving as Bore-hole and a microcontroller-based device with its integrated development to generate a communication message. A flowchart that shows the procedural steps involved was developed. On completion of the prototype, components and sub-circuits effectiveness as well as experimental testing of the system effective operation were carried out. Some anticipated water level (AWL) were selected at interval of 2 centimeters (cm) starting from 3cm and the corresponding Message Operating water level (MOWL) were obtained with error deviations not greater than 0.17cm. Thus the average AWL, average MOWL and the error deviation are 11cm, 10.7cm and 0.1cm. The prototype device thus operated effectively.
Palestinian Women Writers in English: Compromising National and Feminist Agendas
Authors: Jarrad Samah , M. M. Raihanah , Vengadasamy Ravichandran 
Published: May 2024

The article analyses the intersection of Palestinian nationalism and feminism as represented in literary and political discourse. Through an examination of well-established historical discourses surrounding the Palestinian situation, this study reframes the notion that feminist political projects and nationalism are incompatible. By utilizing the framework of postcolonial feminism, this analysis scrutinizes the depiction of Palestinian women in narratives of national struggle as agents, symbols, and authors. Employing historical analysis and literary criticism as sources of data, this article investigates the development of Palestinian women's activism from the early 20th century to the present. It underscores the impact that women had on the Palestinian literary canon, their contributions to the national movement, and the emergence of indigenous feminisms. Notwithstanding the comparatively masculine conception of nationalist agency that permeates Palestinian nationalism, this qualitative study investigates the ways in which national struggle stimulated the advancement of Palestinian women. This encompasses discussions concerning gender awareness and the methods through which women defied cultural and societal norms through active participation in the national struggle and substantial literary contributions. This study is of significant value as it critically examines the complex relationship between feminism and nationalism in the Palestinian context, while also challenging the assumptions made by Western feminism. Through an examination of the experiences and perspectives of Palestinian women, this study underscores the ways in which the concurrent reinforcement of nationalist sentiments and reclamation of feminist narratives empower Palestinian women and bolster support for the Palestinian cause, thus making a significant contribution to the nation's pursuit of independence.
Pengaruh Transformasi Digital Marketing Sebagai Langkah Recovery Bisnis UMKM di Era VUCA
Authors: Manggabarani Alfatih S. , Kresna Iwan , Miftah Munasiron 
Published: May 2024

Perubahan yang masif dalam berbagai aspek kehidupan menciptakan dinamika dan perubahan yang jauh lebih cepat dan beragam dibandingkan apa yang sudah dihadapi selama ini. Akselerasi gelombang perubahan tersebut pada akhirnya membuat semua pihak baik di dunia bisnis, pemerintah, maupun masyarakat menghadapi fenomena volatility, uncertainty, complexity, ambiguity (VUCA). Penelitian ini fokus untuk mengetahui pengaruh penerapan transformasi digital marketing di era VUCA terutama saat pelaku usaha UMKM menghadapi revolusi industri 4.0. Metode penelitian yang digunakan adalah penelitian kuantitatif deskriptif. Metode ini digunakan untuk mengetahui pengaruh penerapan transformasi digital marketing di era VUCA terhadap UMKM. Dampaknya adalah semakin sulit dalam mengidentifikasi hubungan sebab akibat di antara interaksi ini.Sama halnya dengan uncertainty yang membuat pemodelan ekonomi sederhana semakin tidak realistis, kondisi complexity membuat hubungan kausalitas linier dalam pemodelan ekonomi telah mencapai batasnya dan kurang berfungsi lagi.Dengan kata lain, hubungan antar variabel sangat kuat sehingga faktor eksternal dan internal yang sama masih dapat menghasilkan output atau reaksi sistem yang sangat berbeda. Sementara itu dalam ekonomi mikro, misalnya perusahaan manufaktur, semakin tinggi nilai kompleksitas, maka strategi kualitas perlu diprioritaskan untuk meningkatkan kinerjanya. Dengan kata lain, di era VUCA, complexity berpotensi menghasilkan peningkatan kualitas struktural jika berhasil diatasi.
Pengaruh Kepemilikan Institusional, Kepemilikan Manajerial, Dan Kepemilikan Asing Terhadap Pengungkapan Corporate Social Responsibility
Authors: Saptowinarko Prasetyo Margo 
Published: May 2024

Penelitian ini bertujuan untuk memperoleh bukti empiris mengenai pengaruh kepemilikan institusional, kepemilikan manajerial, dan kepemilikan asing terhadap pengungkapan corporate social responsibility. Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling sebanyak 33 sampel perusahaan manufaktur di BEI yang telah melaporkan laporan tahunannya secara berkelanjutan. Metode analisis yang digunakan adalah analisis regresi linear berganda. Hasil pengujian menunjukkan: 1. Kepemilikan Institusional berpengaruh positif tidak signifikan terhadap pengungkapan CSR. 2. Kepemilikan Manajerial memiliki pengaruh negative tidak signifikan terhadap pengungkapan CSR. 3. Kepemilikan Asing memiliki pengaruh negatif tidak signifikan terhadap pengungkapan CSR. 4. Kepemilikan Institusional, Kepemilikan Manajerial, dan Kepemilikan Asing memiliki pengaruh positif dan signifikan terhadap pengungkapan CSR.
Evaluation of the Strength Of R60 Type Rails Against Loading High-Speed Trains
Authors: Dermawan Septa Ade , Widyaningsih Nunung 
Published: May 2024

Currently, Indonesia has entered a new phase in the development of modern transportation infrastructure, namely high-speed trains initiated by PT Kereta Cepat Indonesia China. The design of the facility operated is an Electrical Multiple Unit (EMU) CR400AF that can drive up to speeds of 350 km / h. Of course, high train speed requires the reliability of railway road infrastructure, including the geometry and components of rail roads. The technical specifications of high-speed rail roads have been regulated in the Minister of Transportation Regulation Number 7 of 2022. The type of rail used by high-speed railway line components with a rail road width of 1435 mm is type R60 rail. However, the determination of the type of high-speed railway in Indonesia has not been completed by analyzing the strength of the rail structure in bearing the load working on it. Thus, this study discusses the influence of rail road geometry on the speed of facilities and evaluates the strength of Type R60 rail structures in receiving high-speed train loads. The analysis method uses the Beam on Elastic Foundation (BOEF) method which assumes the behavior of rails as continuous beams that receive loads on elastic foundation pedestals. The results of the study found that the value of the realized radius and minimum radius of the horizontal arch respectively amounted to 9,500 m and 8,502.94 m greater than the horizontal arch permit radius of 7,000 m, while for the value of the permit radius and vertical radius of the vertical arch of 25,000 m. So that the optimization of the horizontal curved radius to 8,502.94 m to be more in line with the ability of the path to serve passing facilities and is expected to be more effective and efficient in planning. The static load and dynamic load of the EMU wheel CR400AF of 81,662.50 N and 243,522.90 N. The maximum voltage and rail clearance voltage were obtained at 134.53 N/mm2 and 228.57 N/mm2. The strength of the rails is written in the form of a safety factor (SF) number. The calculation results show that the most critical SF value of the rail in receiving the load of high-speed trains is 1.70. Based on the results of BoEF calculations, R60 type rails have a high safety value in withstanding static loads and dynamic loads of high-speed trains.
Empowering Adolescents: Cultivating Holistic Growth for Success
Authors: Kumar Vikas , Bahadur Vir Bahadur 
Published: May 2024

One of the most important stages of human development, adolescence, is full of opportunity for significant change. Education serves as a catalyst during this time of self-discovery, going beyond the limitations of typical academic settings. Taking center stage is holistic education, which recognizes the complex interplay between the intellectual, emotional, physical, social, and moral facets that shape the development of adolescents.
This essay explores the essential elements of holistic education and the need to go beyond conventional educational paradigms in order to highlight the importance of empowering teenagers through this kind of education. It promotes adopting thorough evaluations that go beyond simple grades, embracing experiential learning techniques, and incorporating life skills education into academic courses. The study also explores the obstacles to holistic education implementation, such as standardized testing demands, budget constraints, and deeply ingrained reluctance to change in established educational systems.
Airway Analysis in Different Malocclusions - A Cephalometric Study
Authors: R.Hellweg Sheraffin  , Mary Sheloni Missier  , S.D.Milling Tania  , I.Bevin Shaga  , S.Veerasankar  , A. Jebilla Pringle  
Published: May 2024

Background: It was essential to evaluate respiratory function when diagnosing and planning orthodontic treatment. Based on the correlation between pharyngeal airway space and craniofacial structure, airway width was hypothesized to be an indicator of airway patency in different groups of skeletal malocclusion.

Aim: The purpose of this study was to investigate age and gender related changes in pharyngeal airway dimensions in different sagittal skeletal relationships

Materials and Method: Sixty lateral cephalograms of patients aged 10-30 years with no pharyngeal pathology or nasal obstruction were retrospectively selected and categorized into skeletal Class I (n = 20), Class II (n = 20), and Class III (n = 20) malocclusion based on ANB angle. McNamara's airway analysis was used to quantify upper- and lower-airway dimensions. The analyses of intergroup differences were performed using a one-way ANOVA, an independent t-test, and Tukey's test as a post-hoc test.

Results: Participants in the study ranged in age from 20.57 ± 5.41 years (males) and 20.03 ± 4.58 years (females) were included in the study. The upper pharyngeal airway (UPA) dimensions demonstrated a positive correlation with age. In both genders, the mean upper pharyngeal airway (UPA) size exceeded the lower pharyngeal airway (LPA) size, but neither age nor gender was associated with statistically significant differences in skeletal malocclusion.

Conclusion: It was shown that skeletal malocclusions of different types have no effect on the upper and lower pharyngeal airways and that the upper and lower pharyngeal airways are not influenced by age or gender.
Presurgical Naso-alveolar molding in cleft lip and palate patients – A critical review
Authors: Nagaveni N B 
Published: May 2024

Purpose: To evaluate and assess the current scientific evidence pertains to the efficiency and usefulness of Presurgical Naso-alveolar molding (PSNAM) in cleft lip and cleft palate patients.
Methods: A comprehensive scientific literature search was carried out using PUBMED electronic database which focus on the current concept of PSNAM and those which critically analyse its long term effects in the treatment of cleft lip, palate and nasal deformity, using different terminologies like the ‘presurgical nasoalveolar molding’, ‘nasal moulding’ and ‘infant orthopaedics’ and documented articles over a period of 30 years were selected for the critical review.
Results: Following PUBMED search, a total of 58 articles were retrieved. These 58 articles were investigations pertaining to the effect of PSNAM on different aspects of cleft including effects of PSNAM on facial growth, maxillary arch, dentition and occlusion, its effects on nasal symmetry and nasolabial appearance, and on speech.
Conclusions: Presurgical Naso-alveolar molding can be a useful adjunctive treatment modality for management of cleft lip and palate patients. This technique being a cost effective is more beneficial in reducing the number of future surgeries required in the management of cleft lip and palate patients.
PENGELOLAAN SAMPAH KERTAS MENJADI KERAJINAN TANGAN KESENIAN TRADISIONAL BANDUNG
Authors: Bambang Nurcahya Said , Muksin Muksin 
Published: May 2024

Kota Bandung mengalami darutat sampah karena tempat pembuangan akhir sampah mengalami longsor dan kebakaran sehingga dalam beberapa minggu tidak bisa menerima sampah rumah tangga dan sampah industri dari warga kota Bandung. Pemerintah Kota Bandung dalam hal ini Dinas Lingkungan Hidup juga telah mengambil Langkah penangan sampah yaitu diantaranya membangun rumah magot di tiap kelurahan di Kota Bandung, tetapi kegiatan ini masih dilakukan oleh staf dan linmas di kelurahan yang tugasnya sudah banyak sehingga masih belum maksimal dalam penanganannya. Dalam penangan sampah dibandung untuk mempermudah penangan dibuat tiga kategori sampah yaitu sampah rumah tangga dan lingkungan hidup dengan tempat berwarna hijau, sampah kertas, pembungkus dan kaleng dengan tempat berwarna kuning dan sampah kaca, olie, sabun, dan limbah berbahaya lainnya dengan tempat sampah berwarna merah. Agak sulit mengajarkan pemilahan sampah kepada masyarakat terutama bagi yang sudah terbiasa membuang sampah dengan menyatukan di satu tempat dirumahnya, untuk itu peneliti mengajak masyarakat terlibat dalam peduli sampah dari rumah tangga yang sudah dipisahkan menjadi empat kelompok, Limbah berbahaya, Plastik kaleng, Sisa rumah tangga, dan Kertas. Dalam penelitian ini lebih difokuskan pada sampah kertas yang diolah menjadi kerajinan tangan berupa kesenian benjang dan turunan dari kesenian benjang.
Pengaruh Sektor Parawisata Pada Kapasitas Fiskal Daerah: Studi Kasus Toraja Utara
Authors: Bayanuddin Rahayu , Nursini Nursini , Suhab Sultan 
Published: May 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kunjungan wisatawan, jumlah obyek wisata, hotel/akomodasi lainnya, serta restoran/rumah makan terhadap pendapatan asli daerah sektor pariwisata di Kabupaten Toraja. Penelitian ini menggunakan data sekunder yang didapat melalui Kantor Dinas Kebudayaan dan Pariwisata, Kantor Badan Pendapatan Daerah, dan Kantor Badan Pusat Statistik Kabupaten Toraja Utara. Teknik analisis yang digunakan adalah regresi linear berganda menggunakan program SPSS. Hasil penelitian ini menunjukkan dari tahun 2009-2019, kunjungan wisatawan dan obyek wisata, berpengaruh signifikan terhadap Pendapatan Asli Daerah di Kabupaten Toraja Utara. Namun hotel/akomodasi lainnya dan restoran/rumah makan tidak berpengaruh signifikan terhadap Pendapatan Asli Daerah di Kabupaten Toraja Utara.
Changes in the concentration of bone turnover markers in men after maximum intensity exercise
Authors: Bagińska Małgorzata , Tota Łukasz Marcin , Morawska-Tota Małgorzata , Kusmierczyk Justyna , Pałka Tomasz 
Published: May 2024

Background
Physical activity is an important factor in modelling the remodelling and metabolism of bone tissue. The aim of the study was to evaluate the changes in indices demonstrating bone turnover in men under the influence of maximum-intensity exercise.

Methods
The study involved 33 men aged 20–25, divided into two groups: experimental (n = 15) and control (n = 18). People training medium- and long-distance running were assigned to the experimental group, and non-training individuals to the control. Selected somatic, physiological and biochemical indices were measured. The level of aerobic fitness was determined using a progressively increasing graded test (treadmill test for subjective fatigue). Blood samples for determinations were taken before the test and 60 minutes after its completion. The concentration of selected bone turnover markers was assessed: bone fraction of alkaline phosphatase (b-ALP), osteoclacin (OC), N-terminal cross-linked telopeptide of the alpha chain of type I collagen (NTx1), N-terminal propeptide of type I progolagen (PINP), osteoprotegerin (OPG). In addition, the concentration of 25(OH)D3 prior to the stress test was determined. Additionally, pre and post exercise, the concentration of lactates in the capillary blood was determined.

Results
When comparing the two groups, significant statistical differences were found for the mean level of: 25(OH)D3 (p = 0.025), b-ALP (p < 0.001), OC (p = 0.004) and PINP (p = 0.029) prior to the test. On the other hand, within individual groups, between the values pre and post the stress test, there were statistically significant differences for the average level of: b-ALP (p < 0.001), NTx1 (p < 0.001), OPG (p = 0.001) and PINP (p = 0.002).

Conclusion
A single-session maximum physical effort can become an effective tool to initiate positive changes in bone turnover markers.