bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anglais de spécialité et logométrie. L’exemple des débats présidentiels américains
Authors: Bendinelli Marion 
Published: December 2011

Cet article propose d’inscrire l’étude des débats présidentiels américains dans le champ de l’anglais de spécialité et d’y envisager la contribution d’analyses quantitatives empruntées au cadre théorique et méthodologique de la logométrie (Mayaffre 2004). Le corpus d’étude, composé des 22 face-à-face à deux candidats organisés depuis 1960, est traité à l’aide du logiciel Hyperbase. Le relevé lemmatisé des hautes fréquences lexicales montre que les débats sont, sur le plan grammatical, discursif et interactionnel, sensiblement proches du registre conversationnel. Il permet également d’en reconstruire le cadre cognitif (Chilton 2004) et de souligner l’importance donnée aux relations intersubjectives au sein de ce cadre. L’étude des spécificités lexicales des candidats met par ailleurs en évidence le caractère intrinsèquement hybride des pratiques discursives des candidats et confirme l’appartenance des débats présidentiels au genre « discours politique médiatisé » (Fairclough 1995). Cette étude, mêlant analyses qualitatives et quantitatives, contribue à montrer que la logométrie peut outiller la recherche en anglais de spécialité en mettant au jour la structuration discursive, cognitive et générique d’un discours spécialisé.
Problématique de l’insertion professionnelle des personnes «dites» de bas niveau de qualification: d’une approche sociétale à une approche du sujet.
Authors: Biarnès Jean 
Published: December 2011

Interrogeant de manière critique la notion de « bas niveau de qualification », nous identifierons sur quelle « mesure » de l’intelligence et de la compétence elle est construite et à quelles contraintes économiques et technologiques elle répond dans un contexte de productivité et de rentabilité mondialisé. Quels rôles peuvent avoir les professionnels de l’insertion, de quels moyens disposent-ils pour faire reconnaître les compétences liées aux expériences et aux « valeurs du sujet » chez ces publics que les effets de système dans un contexte de mondialisation tendent à précariser et à exclure.
Protection from Secondary Dengue Virus Infection in a Mouse Model Reveals the Role of Serotype Cross-Reactive B and T Cells
Authors: Zompi Simona , Santich Brian H. , Beatty P. Robert , Harris Eva 
Published: December 2011

Abstract
The four dengue virus (DENV) serotypes cause dengue fever and dengue hemorrhagic fever/dengue shock syndrome. Although severe disease has been associated with heterotypic secondary DENV infection, most secondary DENV infections are asymptomatic or result in classic DF. The role of cross-reactive immunity in mediating cross-protection against secondary heterotypic DENV infection is not well understood. DENV infection of IFN-α/β and IFN-γ receptor-deficient (AG129) mice reproduces key features of human disease. We previously demonstrated a role in cross-protection for pre-existing cross-reactive Abs, maintained by long-lived plasma cells. In this study, we use a sequential infection model, infecting AG129 mice with DENV-1, followed by DENV-2 6–8 wk later. We find that increased DENV-specific avidity during acute secondary heterotypic infection is mediated by cross-reactive memory B cells, as evidenced by increased numbers of DENV-1–specific cells by ELISPOT and higher avidity against DENV-1 of supernatants from polyclonally stimulated splenocytes isolated from mice experiencing secondary DENV-2 infection. However, increased DENV-specific avidity is not associated with increased DENV-specific neutralization, which appears to be mediated by naive B cells. Adoptive transfer of DENV-1–immune B and T cells into naive mice prior to secondary DENV-2 infection delayed mortality. Mice depleted of T cells developed signs of disease, but recovered after secondary DENV infection. Overall, we found that protective cross-reactive Abs are secreted by both long-lived plasma cells and memory B cells and that both cross-reactive B cells and T cells provide protection against a secondary heterotypic DENV infection. Understanding the protective immunity that develops naturally against DENV infection may help design future vaccines.
Performance Characteristics of Mucinous (Colloid) Carcinoma of the Breast in Fine-Needle Aspirates: Observations From the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytopathology
Authors: Laucirica Rodolfo , Bentz Joel S , Khalbuss Walid E , Clayton Amy C , Souers Rhona J , Moriarty Ann T 
Published: December 2011

Context.—Mucinous breast carcinoma has characteristic cytologic features, but few studies exist that analyze the reproducibility of this diagnosis.Objective.—To analyze participants' diagnosis of mucinous carcinoma in breast fine-needle aspiration (FNA) slides distributed in an educational interlaboratory peer comparison program.Design.—Participant responses for FNA slides with a reference diagnosis of mucinous carcinoma, distributed between 2001–2008 in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytopathology, were evaluated for concordance with the general category and reference diagnosis of mucinous carcinoma.Results.—Of 8061 responses, 6353 (78.8%) were categorized as malignant; 775 (9.6%) as suspicious; and 933 (11.6%) as negative. The most frequent incorrect responses for the benign category included fibroadenoma (51.7%), nonspecified benign lesion (12%), fibrocystic changes (7.8%), and fat necrosis/granulomatosis/foreign body reaction (6.9%). Conventional Papanicolaou-stained preparations were reviewed for 58.7% (4732) of responses; of these, 39.4% (3177) were from modified Giemsa–stained smears and 1.9% (152) from ThinPrep slides. Papanicolaou-stained conventional smears had the lowest concordance (86.5%) when compared to modified Giemsa–stained smears (91.2%) and ThinPrep challenges (92.1%) (P &lt; .001). Participants specifically diagnosed mucinous carcinoma 37.3% of the time, and modified Giemsa–stained challenges performed best (43.1%, P &lt; .001). There was no significant difference between cytotechnologists' and pathologists' responses (87.9% versus 88.2%; P  =  .69).Conclusions.—Mucinous carcinoma in FNA was not accurately identified in a glass slide interlaboratory comparison program. We observed better performance with modified Giemsa–stained and ThinPrep slides than with Papanicolaou-stained preparations. The most common response for the benign category of mucinous carcinoma was fibroadenoma. Increased awareness of the cytologic features of mucinous carcinoma may improve accuracy in breast FNA.
The Beginnings of Pathology in America: A Contemporary Analysis of William E. Horner's A Treatise on Pathological Anatomy
Authors: Quinonez Guillermo , McLendon William W 
Published: December 2011

Context.—A Treatise on Pathological Anatomy, published in 1829 by William E. Horner, is the first American textbook on pathology. Several articles have been written on Horner, but they do not evaluate the role that the knowledge he recorded played on the intellectual origin of the discipline of pathology in America. Only one article, published in 1930, deals in some detail with the content of the Treatise. Because of new historiographic standards, this is an opportunity to expand on, and update, that article. Furthermore, Horner's book is now available free online, and print-on-demand paperback copies can be ordered for a modest cost from online booksellers.
Objective.—To describe the organization and structure of the scientific knowledge found in the Treatise with the intent of demonstrating how this material created the intellectual basis for the origin of pathology as a discipline in America.
Design.—Using current historiographic standards, the knowledge included in the book is examined and contextualized within the social, professional, and educational conditions existing at the time of publication. The essay also includes biographic data on the author.
Results.—The Treatise contains important information on the principles, ideas, and practice of pathology in the nineteenth century and illustrates the influence of French literature on the author.
Conclusion.—The contribution of the Treatise as the first formal textbook on the subject in America is seminal and should be the basis for further historic studies on the organization and structure of scientific knowledge in pathology in America.
Behavioral and Memory Boosting Effects of Intellan and Cyanocobalamin in Mice
Authors: Najam Rahela , Anser Humera 
Published: December 2011

The aim of this study was to compare the effect of selected drugs, Intellan and cyanocobalamin on some aspects of animal behavior, like effect on memory, depression, gross behavior and exploratory activity. Results of present investigations reveals cyanocobalamin to be a good memory enhancer and intellan also showed memory boosting effects in addition to anti-anxiety activity which affects overall performance.
Evaluation of qualitative methods for phenotyping brachymesophalangia‐V from radiographs of children
Authors: Williams Kimberly D. , Nahhas Ramzi W. , Cottom Carol R. , Lawrence Sharon , Subedi Janardan , Jha Bharat , Czerwinski Stefan A. , Blangero John , Williams‐Blangero Sarah , Towne Bradford 
Published: December 2011

AbstractObjective: Brachymesophalangia‐V (BMP‐V), the general term for a short and broad middle phalanx of the 5th digit, presents both alone and in a large number of complex brachydactylies and developmental disorders. Past anthropological and epidemiological studies of growth and development have examined the prevalence of BMP‐V because small developmental disorders may signal more complex disruptions of skeletal growth and development. Historically, however, consensus on qualitative phenotype methodology has not been established. In large‐scale, non‐clinical studies such as the Fels Longitudinal Study and the Jiri Growth Study, quantitative assessment of the hand is not always the most efficient manner of screening for skeletal dysmorphologies. The current study evaluates qualitative phenotyping techniques for BMP‐V used in past anthropological studies of growth and development to establish a useful and reliable screening method for large study samples.Methods: A total of 1,360 radiographs from Jiri Growth Study participants aged 3–18 years were evaluated. BMP‐V was assessed using three methods: (1) subjective evaluation of length and width of the bone; (2) comparison with skeletal age‐matched radiographs; and (3) subjective evaluation of the length of the middle 4th and 5th phalanges.Results: We found that the method that uses skeletal age‐matched reference radiographs is the better tool for assessing BMP‐V because it considers the shape, rather than solely the length and width of the bone, which can be difficult to judge accurately without measurement. This study highlights the complexity of phenotypic assessment of BMP‐V and by extension other brachydactylies. Am. J. Hum. Biol., 2012. © 2011 Wiley Periodicals, Inc.
ChemInform Abstract: Tetrakis(tetramethylammonium) Tricarbonatodioxidouranate Octahydrate.
Authors: Reed Wendy A. , Oliver Allen G. , Rao Linfeng 
Published: December 2011

AbstractSingle crystals of (Me4N)4 [UO2(CO3)3]·8H2O are grown by slow evaporation (25 °C, 6 weeks) of an aqueous solution of uranyl 1‐hydroxyethane‐1,1‐diphosphonate and Me4NOH.
ChemInform Abstract: Structural and Physical Properties of the New Intermetallic Compound Yb3Pd2Sn2.
Authors: Solokha P. , Curlik I. , Giovannini M. , Lee‐Hone N. R. , Reiffers M. , Ryan D. H. , Saccone A. 
Published: December 2011

AbstractThe title compound is obtained from a stoichiometric melt of the elements and its crystal structure is determined by powder XRD.
ChemInform Abstract: Thioether‐Phosphite: New Ligands for the Highly Enantioselective Ir‐Catalyzed Hydrogenation of Minimally Functionalized Olefins.
Authors: Coll Mercedes , Pamies Oscar , Dieguez Montserrat 
Published: December 2011

AbstractThe new heterodonor ligands readily available from inexpensive natural D‐xylose, combine a good stability with an excellent enantioinduction in the asymmetric hydrogenation of alkenes including challenging 1,1‐disubstituted terminal olefins.
ChemInform Abstract: “On Water” Nucleophilic Addition of Formaldehyde N,N‐Dialkylhydrazones to α‐Keto Esters.
Authors: Crespo‐Pena Ana , Martin‐Zamora Eloisa , Fernandez Rosario , Lassaletta Jose M. 
Published: December 2011

AbstractThe use of water as the reaction mixture is key for the nucleophilic addition of formaldehyde hydrazones to α‐keto esters, leading to highly functionalized carbinols in high yields and short reaction times.
ChemInform Abstract: Expedient Synthesis of N‐Acyl Anthranilamides and β‐Enamine Amides by the Rh(III)‐Catalyzed Amidation of Aryl and Vinylic C—H Bonds with Isocyanates.
Authors: Hesp Kevin D. , Bergman Robert G. , Ellman Jonathan A. 
Published: December 2011

AbstractRhodium‐catalyzed reaction of enamides and anilides with isocyanates provides access to enamine amides, e.g. (III) and (VI), and N‐acyl anthranilamides, e.g. (X) and (VIII).
ChemInform Abstract: A Facile Synthesis of α‐Fluoro Ketones Catalyzed by [Cp*IrCl2]2.
Authors: Ahlsten Nanna , Bartoszewicz Agnieszka , Agrawal Santosh , Martin‐Matute Belen 
Published: December 2011

AbstractThe direct fluorination of allylic alcohols is based on Selectfluor as fluorine source in the presence of iridium catalyst.
ChemInform Abstract: N‐Boc‐O‐Tosyl Hydroxylamine as a Safe and Efficient Nitrogen Source for the N‐Amination of Aryl and Alkyl Amines: Electrophylic Amination.
Authors: Baburaj Thankappan , Thambidurai Sivalingam 
Published: December 2011

AbstractThe reagent (I) is prepared in a two‐step sequence from hydroxylamine, isolated as white crystalline solid and found to be less energetic compared to known amination agents.
ChemInform Abstract: Direct Asymmetric Aldol Reactions in Brine with Recyclable Fluorous β‐Aminosulfonamide Organocatalysts.
Authors: Miura Tsuyoshi , Imai Kie , Kasuga Hikaru , Ina Mariko , Tada Norihiro , Imai Nobuyuki , Itoh Akichika 
Published: December 2011

AbstractA fluorinated diamine organocatalyst is successfully applied in the aldol reaction of various aromatic aldehydes towards cyclic ketones.
ChemInform Abstract: Organocatalytic Asymmetric Sulfa‐Michael Addition of Thiols to 4,4,4‐Trifluorocrotonates.
Authors: Dong Xiu‐Qin , Fang Xin , Wang Chun‐Jiang 
Published: December 2011

AbstractStarting from (E)‐configurated substrates, (S)‐adducts are obtained while the (Z)‐isomers yield the (R)‐products.
ChemInform Abstract: Cyclization Reaction for the Synthesis of Polysubstituted Naphthalenes in the Presence of Au(I) Precatalysts.
Authors: Jagdale Arun R. , Park Jong Hyub , Youn So Won 
Published: December 2011

AbstractTreatment of trisubstituted styrenes and β‐substituted allylic benzenes like (IIIa) and (XV) with AuCl(PPh3)/AgOTf allows access to a number of naphthalene derivatives.
ChemInform Abstract: Ruthenium‐Catalyzed Oxidative C—H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones.
Authors: Ackermann Lutz , Pospech Jola 
Published: December 2011

AbstractThe process allows the preparation of a broad spectrum of phthalides, accompanied in the case of (XVI) by the acrylic acid ester (XVII) as a product resulting from alkenylation/decarboxylation.
ChemInform Abstract: A Facile, Three‐Component Domino Protocol for the Microwave‐Assisted Synthesis of Functionalized Naphtho[2,3‐b]furan‐4,9‐diones in Water.
Authors: Prasanna Pitchaimani , Balamurugan Kamaraj , Perumal Subbu , Menendez J. Carlos 
Published: December 2011

AbstractThe reaction can also be conducted under conventional reflux conditions giving slightly lower yields.
ChemInform Abstract: ZrOCl2·8H2O as a Highly Efficient, Eco‐Friendly and Recyclable Lewis Acid Catalyst for One‐Pot Synthesis of N‐Substituted Pyrroles under Solvent‐Free Conditions at Room Temperature.
Authors: Rahmatpour Ali 
Published: December 2011

AbstractA wide range of N‐substituted title compounds is synthesized by condensation of 2,5‐hexanedione (I) with (hetero)aromatic and aliphatic amines.
ChemInform Abstract: Gluconic Acid Aqueous Solution as a Sustainable and Recyclable Promoting Medium for Organic Reactions.
Authors: Zhou Binghua , Yang Jie , Li Minghao , Gu Yanlong 
Published: December 2011

AbstractThe application of gluconic acid aqueous solution as a new and environmentally friendly solvent in Michael addition reaction of indoles to α,β‐unsaturated ketones, electrophilic ring‐opening reactions of dihydropyran with indoles and Friedel—Crafts alkylation reactions is presented.
ChemInform Abstract: Palladium‐Catalyzed Construction of Polycyclic Heterocycles by an Alkyne Insertion and Direct Arylation Cascade.
Authors: Ohno Hiroaki , Yamamoto Mio , Iuchi Mutsumi , Fujii Nobutaka , Tanaka Tetsuaki 
Published: December 2011

AbstractThe cyclization of bromostyrenes provides a synthesis of hetero‐ or carbocyclic tri‐ and tetracyclic ring systems.
ChemInform Abstract: Cu(II)‐Catalyzed Olefin Migration and Prins Cyclization: Highly Diastereoselective Synthesis of Substituted Tetrahydropyrans.
Authors: Ghosh Arun K. , Nicponski Daniel R. 
Published: December 2011

AbstractTreatment of the alkenols (I) and (IV) with aldehydes in the presence of Cu(O‐Ac)2 and bisphosphine allows convenient and highly stereoselective access to trans‐substituted tetrahydropyrans.
ChemInform Abstract: Iodine/AcCl‐Catalyzed Prins‐Ritter Reaction: Synthesis of 4‐Amido Tetrahydropyrans.
Authors: Srinivasan P. , Perumal P. T. , Raja S. 
Published: December 2011

AbstractHomoallylic alcohols (I), carbonyl compounds (II) or (V) and acetonitrile (III) undergo a smooth Prins‐Ritter‐type cyclization in the presence of iodine/AcCl to produce 4‐acetamido tetrahydropyrans (IV) or (VI) in high yields with all‐cis‐selectivity.
ChemInform Abstract: Enantioselective Synthesis of Polycyclic Coumarin Derivatives Catalyzed by an in situ Formed Primary Amine—Imine Catalyst.
Authors: Zhu Xi , Lin Aijun , Shi Yan , Guo Jingyu , Zhu Chengjian , Cheng Yixiang 
Published: December 2011

AbstractThe imine efficiently promotes the asymmetric Michael addition of cyclic and acyclic enones to 4‐hydroxycoumarins.
ChemInform Abstract: Synthesis of 1‐Aminoisoquinolines via Rh(III)‐Catalyzed Oxidative Coupling.
Authors: Wei Xiaohong , Zhao Miao , Du Zhengyin , Li Xingwei 
Published: December 2011

AbstractA broad spectrum of substrates can be used in the process, where the steric bulk of the C‐aryl ring has a significant influence on the selectivity and efficiency of the procedure.
ChemInform Abstract: Pd‐Catalyzed Direct Cross‐Coupling of Electron‐Deficient Polyfluoroarenes with Heteroaromatic Tosylates.
Authors: Fan Shilu , Yang Jie , Zhang Xingang 
Published: December 2011

AbstractThe method provides a simple, mild, and convenient approach to perfluoroarylated azines and diazines which are of biological interest.
ChemInform Abstract: pH‐Regulated Transfer Hydrogenation of Quinoxalines with a Cp*Ir—Diamine Catalyst in Aqueous Media.
Authors: Tan Jing , Tang Weijun , Sun Yawei , Jiang Zhen , Chen Fei , Xu Lijin , Fan Qinghua , Xiao Jianliang 
Published: December 2011

AbstractTransfer hydrogenation of quinoxalines with sodium formate in aqueous solution proceeds smoothly in the presence of an iridium—trifluoromethylbenzenesulfoxamido ethylenediamine catalyst to give tetrahydroquinoxalines, e.g. (II), (IV), (VI) or (VIII), in excellent yields.
ChemInform Abstract: Stereoselective Glycosylation of endo‐Glycals by Microwave‐ and AlCl3‐Assisted Catalysis.
Authors: Lin Hui‐Chang , Pan Jia‐Fu , Chen Yen‐Bo , Lin Zi‐Ping , Lin Chun‐Hung 
Published: December 2011

AbstractMicrowave‐assisted glycosylation of endo‐glycals with various O‐nucleophiles proceeds smoothly in the presence of catalytic amounts of AlCl3 to give 2‐deoxyglycosides, e.g. (III) or (V), with high α‐stereoselectivity.
Homogeneous Product Quality in Spray Drying with Laminar Operated Rotary Atomizers
Authors: Mescher Axel , Littringer Eva M. , Paus Raphael , Urbanetz Nora A. , Walzel Peter 
Published: December 2011

AbstractDer Einfluss der Zerstäubungsmethode auf die Homogenität sprühgetrockneter Produkte wird diskutiert. Eng verteilte Tropfengrößen sind die Voraussetzung für einheitliche Trocknungsverläufe und Morphologien der Einzelpartikel. Am Beispiel der Sprühtrocknung von Polyvinylpyrrolidon und D‐Mannitol aus wässriger Lösung wird die laminar betriebene Rotationszerstäubung als geeignete Zerstäubungsmethode für ein eng verteiltes System angewendet. Durch die wenig streuenden Trocknungsbedingungen werden für die verwendeten Stoffsysteme homogene Pulvereigenschaften erzielt. Die besonderen Anforderungen, die die eingesetzte Zerstäubungsmethode an die Heißgasführung im Sprühtrockner stellt, werden erläutert und eine neue Gasverteilungsgeometrie vorgestellt.
On‐Column Solvent‐Free Oxidative Cleavage Reactions of Vicinal Diols by Silica Gel and Paraperiodic Acid: Application to In‐Situ Sequential Oxidation and Knoevenagel Reactions
Authors: Dakdouki Saada C. , Villemin Didier , Bar Nathalie 
Published: December 2011

AbstractAn on‐column solvent‐free oxidative cleavage reaction of vicinal diols by paraperiodic acid supported on silica gel at room temperature is described. The resulting pure carbonyl compounds are prepared in good to excellent yields with short reaction times. The cleavage reactions proceed under mild conditions, which avoids further cyclization reactions of the product dialdehydes. This method is also used for sequential oxidation and Knoevenagel reactions to prepare condensation products in good yields by using paraperiodic acid on a mixed bed of alumina and silica gel.
The need for operational reasoning in data‐driven rating curve prediction of suspended sediment
Authors: Mount Nick J. , Abrahart Robert J. , Dawson Christian W. , Ab Ghani Ngahzaifa 
Published: December 2011

AbstractThe use of data‐driven modelling techniques to deliver improved suspended sediment rating curves has received considerable interest in recent years. Studies indicate an increased level of performance over traditional approaches when such techniques are adopted. However, closer scrutiny reveals that, unlike their traditional counterparts, data‐driven solutions commonly include lagged sediment data as model inputs, and this seriously limits their operational application. In this paper, we argue the need for a greater degree of operational reasoning underpinning data‐driven rating curve solutions and demonstrate how incorrect conclusions about the performance of a data‐driven modelling technique can be reached when the model solution is based upon operationally invalid input combinations. We exemplify the problem through the re‐analysis and augmentation of a recent and typical published study, which uses gene expression programming to model the rating curve. We compare and contrast the previously published solutions, whose inputs negate their operational application, with a range of newly developed and directly comparable traditional and data‐driven solutions, which do have operational value. Results clearly demonstrate that the performance benefits of the published gene expression programming solutions are dependent on the inclusion of operationally limiting, lagged data inputs. Indeed, when operationally inapplicable input combinations are discounted from the models and the analysis is repeated, gene expression programming fails to perform as well as many simpler, more standard multiple linear regression, piecewise linear regression and neural network counterparts. The potential for overstatement of the benefits of the data‐driven paradigm in rating curve studies is thus highlighted. Copyright © 2011 John Wiley & Sons, Ltd.