bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing Research on Children With Speech-Language Impairment: An Introduction to the Early Childhood Longitudinal Study—Kindergarten Cohort
Authors: Mashburn Andrew J. , Myers Sonya S. 
Published: January 2010

Purpose
The Early Childhood Longitudinal Study—Kindergarten Cohort (ECLS–K; U.S. Department of Education, 2000) includes comprehensive assessments of home, classroom, and school contexts and developmental outcomes for a nationally representative sample of more than 20,000 children who began kindergarten in 1998–1999. The purposes of this article are to describe the ECLS–K and provide an example of how to use these data to advance speech-language-hearing research.

Method
Special education questionnaires were analyzed from subsamples of children with diagnosed disabilities. The frequencies of different disabilities at kindergarten, 1st, 3rd, and 5th grade were calculated, and for children whose primary diagnosis was speech-language impairment, special education experiences were summarized.

Results
There are relatively large subsamples of children with learning disabilities, physical disabilities, and speech-language impairments. Among children with speech-language impairments, there is substantial variability in special education experiences with regard to the amount of time children received services, location of services, types of instructional methods, and extent to which modifications were made to the general education curriculum.

Conclusion
The comprehensive assessments, large subsamples of children with diagnosed disabilities, and detailed information about special education services makes the ECLS–K a useful resource for advancing the development of theory, effective classroom practices, and evidence-based policies that promote the well-being of children with special needs.
The National Outcomes Measurement System for Pediatric Speech-Language Pathology
Authors: Mullen Robert , Schooling Tracy 
Published: January 2010

Purpose
The American Speech-Language-Hearing Association’s (ASHA’s) National Outcomes Measurement System (NOMS) was developed in the late 1990s. The primary purpose was to serve as a source of data for speech-language pathologists (SLPs) who found themselves called on to provide empirical evidence of the functional outcomes associated with their clinical services for child and adult clients who were exhibiting various speech-language pathologies. The present discourse focuses on data that were collected in school settings from the prekindergarten NOMS and the K–12 NOMS. This initial account describes how the data collection systems were developed and the data were collected as well as an overview of the information contained in these databases.

Method
ASHA’s Functional Communication Measures (FCMs) were used to describe the disorder-specific communicative dysfunction(s) of each student. These data were obtained at the initiation of a child’s speech-language pathology services and again at the time of discharge from these treatments by the SLP.

Results
As of December 2007, data on more than 2,000 preschool students and 14,000 K–12 students have been reported to these 2 NOMS components by SLPs working in school settings.

Discussion
The availability of these data has proven to be a very valuable tool with respect to the efforts of school-based SLPs and administrators to document the beneficial impact of speech-language pathology services in school settings.
The EpiSLI Database: A Publicly Available Database on Speech and Language
Authors: Tomblin J. Bruce 
Published: January 2010

Purpose
This article describes a database that was created in the process of conducting a large-scale epidemiologic study of specific language impairment (SLI). As such, this database will be referred to as the EpiSLI database. Children with SLI have unexpected and unexplained difficulties learning and using spoken language. Although there is no uniform standard for the diagnosis of SLI, the construct encompasses a language deficit occurring in the presence of grossly normal sensory and nonverbal cognitive abilities (H. Tager-Flusberg & J. Cooper, 1999). Although these language difficulties are most apparent during the preschool and early school years, evidence now exists that these problems are usually present well into adulthood and are probably present throughout a person’s life (see, for instance, C. J. Johnson et al., 1999; S. E. Stothard, M. J. Snowling, D. V. M. Bishop, B. B. Chipchase, & C. A. Kaplan, 1998; J. B. Tomblin, 2008).

Discussion
Much of what we know of these children has come from research on children who have been clinically identified and served. Certainly, by studying those who are being served, our research base is most likely to be relevant to clinical services. However, there is a danger in this research strategy. It is quite possible that not all children with SLI are clinically identified and served within our service delivery systems. In such circumstances, there is the potential for systematic factors to influence which children do or do not find their way to clinical service.

Clinical Implications
If our research questions are concerned with the characteristics of the actual population of children with SLI that exists in our communities and not just those who are being served, then we need to turn to methods of epidemiology to aid our research.
Data Recycling: Using Existing Databases to Increase Research Capacity in Speech-Language Development and Disorders
Authors: Justice Laura M. , Breit-Smith Allison , Rogers Margaret 
Published: January 2010

Purpose
This clinical forum was organized to provide a means for informing the research and clinical communities of one mechanism through which research capacity might be enhanced within the field of speech-language pathology. Specifically, forum authors describe the process of conducting secondary analyses of extant databases to answer questions of relevance to speech and language development and disorders.

Method
This prologue defines the concept of secondary analysis of databases and provides an overview of each of the articles that make up the forum.

Conclusion
Researchers invested in addressing basic and applied problems of relevance to speech and language services in schools can make use of a variety of extant databases to increase research capacity.
Structural studies on the full‐length LysR‐type regulator TsaR from Comamonas testosteroni T‐2 reveal a novel open conformation of the tetrameric LTTR fold
Authors: Monferrer Dominique , Tralau Tewes , Kertesz Michael A. , Dix Ina , Solà Maria , Usón Isabel 
Published: January 2010

SummaryLysR‐type transcriptional regulators (LTTRs) constitute the largest family of regulators in prokaryotes. The full‐length structures of the LTTR TsaR from Comamonas testosteroni T‐2 and its complex with the natural inducer para‐toluensulfonate have been characterized by X‐ray diffraction. Both ligand‐free and complexed forms reveal a dramatically different quaternary structure from that of CbnR from Ralstonia eutropha, or a putative LysR‐type regulator from Pseudomonas aeruginosa, the only other determined full‐length structures of tetrameric LTTRs. Although all three show a head‐to‐head tetrameric ring, TsaR displays an open conformation, whereas CbnR and PA01‐PR present additional contacts in opposing C‐terminal domains that close the ring. Such large differences may be due to a broader structural versatility than previously assumed or either, reflect the intrinsic flexibility of tetrameric LTTRs. On the grounds of the sliding dimer hypothesis of LTTR activation, we propose a structural model in which the closed structures could reflect the conformation of a ligand‐free LTTR, whereas inducer binding would bring about local changes to disrupt the interface linking the two compact C‐terminal domains. This could lead to a TsaR‐like, open structure, where the pairs of recognition helices are closer to each other by more than 10 Å.
A reduced segment II/III graft for neonatal liver failure with absence of detectable hepatocytes. A case report and literature review
Authors: Alawi Khalil , Mitros Frank A. , Bishop Warren P. , Rayhill Stephen , Wu Youmin 
Published: January 2010

Alawi K, Mitros FA, Bishop WP, Rayhill S, Wu Y. A reduced segment II/III graft for neonatal liver failure with absence of detectable hepatocytes. A case report and literature review. Pediatr Transplantation 2011: 15:e60–e63. © 2010 John Wiley & Sons A/S.Abstract:  When hepatic failure occurs in newborns, most cases are because of viral hepatitis, metabolic diseases, and neonatal hemochromatosis. It is rare to have liver failure presenting in the first day after birth. We report a unique case of a newborn baby with liver failure in the first day of life who received a reduced segment II and III graft when she was 19 days old and became the youngest survivor of LDLT. Common and rare causes of liver failure in this age group were excluded by appropriate testing. She underwent a liver biopsy that showed a liver devoid of hepatocytes. Similar pathological findings were found in the explanted liver. She was discharged from the hospital with normal graft function three months after the transplant.
Identification and Characterization of a New Strain of Sunflower chlorotic mottle virus, a Potyvirus Infecting Asteraceae in Argentina
Authors: Giolitti Fabian J. , Bejerman Nicolas E. , De Breuil Soledad , Lenardon Sergio L. 
Published: January 2010

AbstractSunflower (Helianthus annuus L.) plants with chlorotic ringspot symptoms were observed during the 2005–2006 crop season in the Southeast of the province of Buenos Aires, Argentina. Symptomatic plants were tested by biological, serological and molecular assays, and the virus isolated was identified as a potyvirus closely related to Sunflower chlorotic mottle virus, common isolate (SuCMoV‐C), the most prevalent virus in sunflower crops in the country. Infected plants were serologically positive when probed with a SuCMoV‐C antiserum. In the 3′‐terminus region, 1304 nucleotides (nt) were sequenced, and it includes the C‐terminal region of the nuclear inclusion b protein (NIb) gene (240 nt), the whole capsid protein (CP) gene (807 nt) and a 3′‐non‐coding region (3′‐NCR) with 257 nt excluding the poly (A) tail. The CP of the Sunflower potyvirus causing chlorotic ringspot (CRS) shared 94.8% aa identity with SuCMoV‐C and 89.2% with SuCMoV‐Zi. The 3′‐NCR shared 94.2% nt sequence identity with SuCMoV‐C. A RT‐PCR/RFLP assay with PvuII and EcoRV restriction enzymes successfully differentiated SuCMoV‐C and the virus isolate causing CRS symptoms. This potyvirus was identified as a new SuCMoV strain, provisionally designated SuCMoV‐CRS.
DNA Fragmentation in Canine Immature Grade 1 Cumulus‐Oocyte Complexes
Authors: Lopes G , Vandaele L , Rijsselaere T , Van Soom A , Rocha A 
Published: January 2010

ContentsIn this work, we studied the incidence of DNA fragmentation, interpreted as apoptotic changes and assessed by the TUNEL assay, in cumulus cells and oocytes of immature Grade 1 cumulus‐oocyte complexes (COCs) obtained from healthy bitches (n = 27) of three age groups: young (1–3 years; n = 13), adult (4–6 years; n = 8) and elderly (7–10 years; n = 6). Age affected (p < 0.05) Grade 1 COCs recovery rates, with young animals yielding more (p < 0.01) Grade 1 COCs than the other two age groups. Conversely, no differences were observed in the incidence of DNA fragmentation (TUNEL‐positive) in cumulus cells or oocytes between the three age groups. Overall, more than 80% of Grade 1 COCs presented <15% of TUNEL‐positive cumulus cells and enclosed TUNEL‐negative (intact DNA) oocytes. Despite a higher proportion of TUNEL‐negative oocytes being found in the germinal vesicle stage, most of the oocytes with nuclear material compatible with meiosis resumption (MR) or with non‐identifiable nuclear material (ND) did not present DNA fragmentation. No correlation was observed between DNA fragmentations in oocytes and in cumulus cells. We concluded that the morphological parameters used to classify canine Grade 1 COCs are reliable to select a homogeneous population of COCs with low incidence of DNA fragmentation. Furthermore, these results indicate that DNA fragmentation can only explain a minor proportion of the incidence of MR and degeneration in canine oocytes at collection.
Investigation into the occupational lives of healthy older people through their use of time
Authors: Chilvers Rachel , Corr Susan , Singlehurst Hayley 
Published: January 2010

Background/aim:  Older people are one of the largest groups using health‐care services; therefore, it is important for occupational therapists to have an understanding of their occupational lives. Temporality is a key element of occupation, yet little research exists regarding older people and time use, despite the considerable temporal adjustments taking place at this lifestage. The aim of this study was to identify the occupational lives of healthy older people through the activities they undertake in a 24‐hour period. Method:  Data analysis of time‐use diaries from 90 older UK residents (aged 60–85 years) who considered themselves to be healthy was undertaken, using 15 activity codes and three pre‐coded terms: necessary, enjoyable and personal. Results:  The participants spent most of their time sleeping and resting (34%), followed by performing domestic activities (13%), watching television, listening to the radio or music, or using computers (11%), eating and drinking (9%) and socialising (6%). Enjoyable activities occupied most of their time (42% of the day), followed by necessary (34%) and personal activities (16%). Conclusion:  These data contribute to the growing evidence base regarding older people as occupational beings, indicating that they are a diverse group of individuals who are meeting their needs with dynamic, positive activities. This highlights the importance of a client‐centred approach to occupational therapy, as it enables the clients to have choice, control and diversity in their activities when meeting their needs.
High prevalence of antibodies against Bartonella henselae with cervical lymphadenopathy in children
Authors: Asano Takeshi , Ichiki Kunihiko , Koizumi Shinya , Kaizu Kiyohiko , Hatori Takayuki , Fujino Osamu 
Published: January 2010

AbstractBackground:  Cat‐scratch disease is the most common form of Bartonella henselae infection. Although reports have shown that CSD is relatively common, they have not shown the prevalence of seropositivity for Bartonella henselae in cases of cervical lymphadenitis and Kawasaki disease, which are relatively common diseases in children.Methods:  We evaluated the presence of immunoglobulin (Ig) G‐ and IgM‐class antibodies against Bartonella henselae in children with cervical lymphadenitis, Kawasaki disease, and infectious diseases without lymphadenopathy in a semi‐rural area in Japan.Results:  We found that the positivity rate for the IgG antibody against Bartonella henselae in patients with cervical lymphadenitis who owned cats or dogs was significantly higher than that in patients with Kawasaki disease and infectious diseases without lymphadenopathy. However, the average age of children with cervical lymphadenitis did not significantly differ when compared to those with other infectious diseases.Conclusion:  Our serological study showed that Bartonella henselae infection may contribute to the etiology of cervical lymphadenitis in children.
Serum and urinary neutrophil gelatinase‐associated lipocalin levels in children with chronic renal diseases
Authors: Nishida Masashi , Kawakatsu Hidekazu , Okumura Yasuko , Hamaoka Kenji 
Published: January 2010

AbstractBackground:  Recent studies showed that serum and urinary neutrophil gelatinase‐associated lipocalin (NGAL) represents a novel, sensitive, specific biomarker for early detection of acute kidney injury. However, the clinical significance of measuring serum and urinary NGAL on chronic renal diseases remains unclear.Methods:  In this study, we measured serum and urinary NGAL levels in patients with several common pediatric renal diseases such as renal dysfunction (estimated glomerular filtration rate < 90 mL/min/1.73 m2), proliferative glomerulonephritis, steroid‐resistant and steroid‐sensitive nephrotic syndrome, and tubular dysfunction.Results:  Urinary NGAL level was significantly increased compared with the control in all of these disease groups except in patients with a remission stage of steroid‐sensitive nephrotic syndrome, although a significant increase in serum NGAL level was observed in the renal dysfunction group only. Both serum and urinary NGAL levels showed significant inverse correlations with an estimated glomerular filtration rate in the analysis with total subjects, and also in the analysis with the renal dysfunction group in urinary NGAL. In proteinuric patients, the extent of proteinuria significantly correlated with urinary NGAL level. In patients with tubular dysfunction, the increase of urinary NGAL level was remarkable compared with the other disease groups.Conclusion:  These results indicated that urinary NGAL level is a better biomarker for chronic renal diseases in children than serum NGAL level, although multiple pathological mechanisms should be considered in evaluating these NGAL values.
The Pedagogy of Slowing Down: Teaching Talmud in a Summer Kollel
Authors: Kanarek Jane 
Published: January 2010

AbstractThis article explores a set of practices in the teaching of Talmud called “the pedagogy of slowing down.” Through the author's analysis of her own teaching in an intensive Talmud class, “the pedagogy of slowing down” emerges as a pedagogical and cultural model in which the students learn to read more closely and to investigate the multiplicity of meanings inherent in the Talmudic text, thus bridging the gap between an ancient text and its contemporary students. This article describes the specific techniques in the pedagogy of slowing down, and the ways in which this teaching practice contributes both to students' becoming more attentive readers and to the ongoing development of their religious voices.
Three Reviews of For Life Abundant: Practical Theology, Theological Education, and Christian Ministry, edited by Dorothy C. Bass and Craig Dykstra, 2008
Authors: Slough Rebecca , Stortz Martha E. , Kwok Pui‐lan 
Published: January 2010

Abstract For Life Abundant, the fruit of sustained reflection among systematic theologians, practical theologians, and pastors, is an important new work that deserves attention. The volume provokes creative and critical thinking about practical theology. Its contributors conceptualize the field as a disciplined practice of imagination and skill residing at the confluence of Christian tradition and living ecclesial communities, and ask what such a construal of practical theology might mean for theological education.Given the significance of For Life Abundant, Teaching Theology and Religion asked three theological educators who are located in different regions, types of institutions, and fields, to review and respond to it. Rebecca Slough describes the volume's central questions and organization, and considers how it might contribute to the deliberations of a seminary faculty regarding a school's curriculum. Martha Stortz shows how the process and structure of For Life Abundant are in themselves illustrative of the conceptualization of practical theology for which it argues. Kwok Pui‐lan notes the volumes strengths and goes on to probe its lacunae, particularly with regard to global, gender, and multi‐cultural considerations relevant to a robust construal of pastoral theology in our time.While the authors of these three reviews and responses to the volume did not interact as they wrote them, together they comprise a conversation that should be on‐going. TTR invites further responses to the volume.
God's Stuff: The Constructive Powers of Chaos For Teaching Religion
Authors: Willhauck Susan 
Published: January 2010

AbstractOrder and organization are valued in the classroom, and there is a prevailing understanding that chaos should be avoided. Yet chaos can also be potent space or a source from which new things spring forth. This article investigates biblical, scientific, and cultural understandings of chaos to discover how these contribute to a revelatory metaphor for teaching. It examines Catherine Keller's engagement with chaos theory in creation theology for pedagogical implications. Using a framework suggested in the work of Mary Elizabeth Moore, the author interprets powers and practices of chaos teaching and provides examples of how the metaphor plays out in the teaching of religion and theology.
Risks for methicillin‐resistant Staphylococcus aureus colonization or infection among patients with HIV infection*
Authors: Ramsetty SK , Stuart LL , Blake RT , Parsons CH , Salgado CD 
Published: January 2010

BackgroundRisks for methicillin‐resistant Staphylococcus aureus (MRSA) among those with HIV infection have been found to vary, and the epidemiology of USA‐300 community‐acquired (CA) MRSA has not been adequately described.MethodsWe conducted a retrospective review of HIV‐infected out‐patients from January 2002 to December 2007 and employed multivariate logistic regression (MLR) to identify risks for MRSA colonization or infection. Pulsed‐field gel electrophoresis (PFGE) was used to identify USA‐300 strains.Results Seventy‐two (8%) of 900 HIV‐infected patients were colonized or infected with MRSA. MLR identified antibiotic exposure within the past year [odds ratio (OR) 3.4; 95% confidence interval (CI) 1.5–7.7] and nadir CD4 count <200 cells/μL (OR 2.5; 95% CI 1.2–5.3) as risks for MRSA colonization or infection. Receipt of antiretroviral therapy (ART) within the past year was associated with decreased risk (OR 0.16; 95% CI 0.07–0.4). Eighty‐nine percent of available strains were USA‐300. MLR identified skin or soft tissue infection (SSTI) as the only predictor for infection with USA‐300 (OR 5.9; 95% CI 1.4–24.3).Conclusion Significant risks for MRSA among HIV‐infected patients were CD4 count nadir <200 cells/μL and antibiotic exposure. Only the presence of an SSTI was associated with having USA‐300, and thus the use of patient characteristics to predict those with USA‐300 was limited. In addition, ART within the previous year significantly reduced the risk of MRSA colonization or infection.
Enabling self‐directed computer use for individuals with cerebral palsy: a systematic review of assistive devices and technologies
Authors: DAVIES T CLAIRE , MUDGE SUZIE , AMERATUNGA SHANTHI , STOTT N SUSAN 
Published: January 2010

Aim  The purpose of this study was to systematically review published evidence on the development, use, and effectiveness of devices and technologies that enable or enhance self‐directed computer access by individuals with cerebral palsy (CP).Methods  Nine electronic databases were searched using keywords ‘computer’, ‘software’, ‘spastic’, ‘athetoid’, and ‘cerebral palsy’; the reference lists of articles thus identified were also searched. Thirty articles were selected for review, with 23 reports of development and usability testing of devices and seven evaluations of algorithms to increase computer recognition of input and cursor movements.Results  Twenty‐four studies had fewer than 10 participants with CP, with a wide age range of 5 to 77 years. Computer task performance was usually tested, but only three groups sought participant feedback on ease and comfort of use. International standards exist to evaluate effectiveness of non‐keyboard devices, but only one group undertook this testing. None of the study designs were higher than American Academy for Cerebral Palsy and Developmental Medicine level IV.Interpretation  Access solutions for individuals with CP are in the early stages of development. Future work should include assessment of end‐user comfort, effort, and performance as well as design features. Engaging users and therapists when designing and evaluating technologies to enhance computer access may increase acceptance and improve performance.