bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFEKTIVITAS KOMBINASI FISIOTERAPI DADA DAN SUCTION TERHADAP PENURUNAN PRODUKSI SPUTUM PADA PASIEN GAGAL NAFAS DI RUANG ICU RUMAH SAKIT SWASTA 2024: CASE REPORT
Authors: Afrianus Afrianus  , Diah Pujiastuti  , Anjarwati Margaretha Rina 
Published: May 2024

Respiratory failure is a failure in the gas exchange function between oxygen and carbon dioxide which can cause decreased consciousness. One of the complications of decreased consciousness that is often encountered is sputum retention. The intervention carried out was chest physiotherapy combined with suction. Based on a preliminary study, it was found that 24 (80%) experienced respiratory failure. To reduce sputum production in patients with respiratory failure with chest physiotherapy intervention combined with suction in the ICU of a private hospital. The research method used in this research is a case report by conducting intervention observations and also airway clearance research with 1 respondent. After chest physiotherapy combined with suction, the results showed an increase in oxygen saturation from 88% to 99% and sputum production decreased from ± 10 cc to ± 7 cc. After chest physiotherapy combined with suction for 3 days, significant results were obtained, namely an increase in oxygen saturation and also a decrease in sputum production. ICU nurses are expected to be able to apply chest physiotherapy combined with suction to reduce sputum production in patients with respiratory failure in the ICU by paying attention to vital signs. Intervention is carried out once a day.
Histopathological Detection of the Protective Role of Hydroxytyrosol Against the adverse Effect of Azithromycin in Rats
Authors: Neamah Ghusoon Abdul Kareem , Alalwany Ekhlas Abid hamza , Rabee Fadak Bahaa , Jasim Adnan Mansour , Abukhomra Ahmed Samir , Abukhomra Ahmed Samir 
Published: May 2024

Background: Adverse medication reactions affecting one or more organ systems can manifest as side effects of antibiotics. There is a possibility that some antibiotics will have adverse effects that are fatal. The present study aims to examine the ability of hydroxytyrosol (HT) to protect the liver, heart , and improvement of kidney function against the adverse effects of azithromycin.Methods: Thirty adult male rats were randomly divided into three equal groups of 10 animals each. The first group, designated negative control (NC), was the daily oral administration of normal saline. The second group (T1) was subject to daily oral administration of azithromycin (30 mg/kg). The last third group (T2) was administered azithromycin (30 mg/kg) with hydroxytyrosol (50 mg/kg). After two weeks the animals were sacrificed for serum collection, histopathological specimens, and drug docking evaluation using Auto Dock Vina.Result: The present study showed that score binding in 18gs Glutathione S-transferase was preferable in hydroxytyrosol with (-5.95 Kcal/mol), while vitamin E was in (-7.80 Kcal/mol) and (-6.16 Kcal/mol) for glutathione. On the other aspect, antioxidant coenzyme Q10 showed less binding with 18gs Glutathione S-transferase to recorded binding at (-4.9) with Root Mean Square Deviation (RMSD) (29.3, 30.3, 23.9 Kcal/mol) and (28.6) Kcal/mol, respectively. The histopathological result for T1 showed several histological effects in the liver, heart, and kidney, while in T2 group showed improvement in tissue architecture. Conclusion: The study concluded that hydroxytyrosol binding glutathione S-transferase could predict potent antioxidants near glutathione, might be responsible for scavenger free radicals, and protect the tissue against the toxic effects of azithromycin.Keywords: Histopathology; Rat; Hydroxytyrosol; Azithromycin; Glutathione S-transferase
IMPACT OF USE OF SOCIAL APPLICATIONS AND APPEARANCE-RELATED CONSCIOUSNESS ON BODY DYSMORPHIC DISORDER SYMPTOMS AND LOWER SELF-ESTEEM AMONG FEMALES
Authors: Waqar Laiba , Mazhar Arooj Fatima , Rafique Maria , Rehman MIsbah 
Published: May 2024

Objective: To investigate the impact of use of social applications and appearance-related consciousness on Body dysmorphic disorder symptoms and lower self-esteem among females.
Research Design: Study uses cross-sectional research design to examine the association of social applications and appearance-related consciousness with symptoms of body dysmorphic disorder and lower self-esteem.
Place and duration of study: The study was conducted in 6 months at Riphah International University from January to August 2022.
Methods: A total of 200 females were approached via convenience sampling for this study from universities, colleges and workplace of Pakistan. Female participants of age range young adults i. e. 17-35 years were included in study. Females actively using social media for more than 6 months were recruited.
Results: According to the results it was found that social application use and appearance-related conciseness both were positively related to symptoms of body dysmorphic disorder. However, it was showed that social application use and appearance-related conciseness were negatively related to self -esteem.
Conclusion: The present study demonstrated that individuals who excessively use social applications and are more likely to be unhappy with their own body image and experience more negative feelings after viewing appealing self-images on social media. Higher body dysmorphic and worse self-esteem were revealed to be positively correlated with appearance-related awareness.
Septuaginta som udfordring til den bibelske kanon
Authors: Müller Mogens 
Published: May 2024

ENGLISH SUMMARY: When Jerome working on a new edition of the Latin Bible, around 390 decided to replace the Greek Septuagint with the Hebrew Bible (Hebraica veritas), it meant a farewell to what until then exclusively had been the first Bible of the church. Jerome did not wish to translate a translation and reckoned outright the Hebrew text the original. In the era of the reformation, Luther overtook this understanding, and the various protestant churches had a translation of the Hebrew Bible as their Old Testa-ment. New insights in both the complicated history of the Hebrew text in Antiquity, and in the special theological character of the Septuagint as the Bible of Hellenistic Judaism, today confronts us with a question: Shall we continue considering Biblia Hebraica the on-ly legitimate text of the Old Testament? Or, invites our knowledge about the genesis of the Septuagint, its special theological character, its meaning for the authors of the New Testament scriptures and its history in the first centuries of the church, to juxtapose the two editions of the Old Testament as equal editions of the church’s Old Testament? By exclusively preferring Biblia Hebraica, a foundational chapter in the reception history is omitted, and the Septuagint is left behind as a “missing link”. In the churchly and theo-logical context of today, Septuagint thus constitutes a challenge to our present under-standing of canon.

DANSK RESUME: Da Hieronymus under arbejdet med en ny udgave af den latin-ske Bibel omkring 390 besluttede sig for i stedet for den græske Septuaginta at lægge den hebraiske tekst (Hebraica veritas) til grund, betød det en afsked med det, der el-lers havde været kirkens første Bibel. Hieronymus ville ikke oversætte en oversættelse og anså ligefrem den hebraiske tekst for ’grundteksten’. Denne forståelse overtog Lu-ther på reformationstiden, og for de reformatoriske kirker har deres biblers Det Gamle Testamente bestået af oversættelser af Biblia Hebraica. Nye indsigter i såvel mangfol-digheden i overleveringen i antikken af den hebraiske bibeltekst som den teologiske prægning, som Septuaginta fik som en hellenistisk jødedoms samling af hellige skrif-ter, stiller os i dag over for det spørgsmål, om vi fortsat skal holde fast ved Biblia He-braica som den legitime bibeltekst, eller om vi ikke ud fra den viden, vi i dag har om Septuagintas tilblivelse og karakter, må sidestille de to bibeltekster, når det gælder kirkens og teologiens Gamle Testamente. Septuaginta var således bibelteksten for for-fatterne til Det Nye Testamentes skrifter og har i høj grad været med til at præge denne skriftsamlings teologi. Foretrækkes Biblia Hebraica alligevel eksklusivt som Det Gamle Testamentes tekst, overspringer man et afgørende kapitel i receptionshistorien og får Septuaginta til at stå tilbage som et ”missing link”. På den måde er Septuaginta en udfordring til kirkens og teologiens nuværende kanonforståelse.
Variation and trade-offs in life history traits of the protist parasite Monocystis perplexa (Apicomplexa) in its earthworm host Amynthas agrestis
Authors: Keller Erin L. , Schall Jos. J. 
Published: May 2024

The life history of a parasite describes its partitioning of assimilated resources into growth, reproduction, and transmission effort, and its precise timing of developmental events. The life cycle, in contrast, charts the sequence of morphological stages from feeding to the transmission forms. Phenotypic plasticity in life history traits can reveal how parasites confront variable environments within hosts. Within the protist phylum Apicomplexa major clades include the malaria parasites, coccidians, and most diverse, the gregarines (with likely millions of species). Studies on life history variation of gregarines are rare. Therefore, life history traits were examined for the gregarine Monocystis perplexa in its host, the invasive earthworm Amynthas agrestis at three sites in northern Vermont, United States of America. An important value of this system is the short life-span of the hosts, with only seven months from hatching to mass mortality; we were thus able to examine life history variation during the entire life cycle of both host and parasite. Earthworms were collected (N = 968 over 33 sample periods during one host season), then parasites of all life stages were counted, and sexual and transmission stages measured, for each earthworm. All traits varied substantially among individual earthworm hosts and across the sites. Across sites, timing of first appearance of infected earthworms, date when transmission stage (oocysts packed within gametocysts) appeared, date when number of both feeding (trophic) cells and gametocysts were at maximum, and date when 100% of earthworms were infected differed from 2–8 weeks, surprising variation for a short season available for parasite development. The maximal size of mating cells varied among hosts and across sites and this is reflected in the number of oocysts produced by the gametocyst. A negative trade-off was observed for the number of oocysts and their size. Several patterns were striking: (1) Prevalence reached 100% at all sites by mid season, only one to three weeks after parasites first appeared in the earthworms. (2) The number of parasites per host was large, reaching 300 × 103 cells in some hosts, and such high numbers were present even when parasites first appeared in the host. (3) At one site, few infected earthworms produced any oocysts. (4) The transmission rate to reach such high density of parasites in hosts needed to be very high for a microbe, from >0.33% to >34.3% across the three sites. Monocystis was one of the first protist parasites to have its life cycle described (early 19th century), but these results suggest the long-accepted life cycle of Monocystis could be incomplete, such that the parasites may be transmitted vertically (within the earthworm’s eggs) as well as horizontally (leading to 100% prevalence) and merogony (asexual replication) could be present, not recognized for Monocystis, leading to high parasitemia even very early in the host’s season.
Hsa_circ_0009096/miR-370-3p modulates hepatic stellate cell proliferation and fibrosis during biliary atresia pathogenesis
Authors: Wu Zhouguang , Wang Bin , Chen Siqi , Zuo Taoyan , Zhang Wenjie , Cheng Zhen , Fu Jingru , Gong Jiafeng 
Published: May 2024

Background
Hepatic stellate cell (HSC) activation and hepatic fibrosis mediated biliary atresia (BA) development, but the underlying molecular mechanisms are poorly understood. This study aimed to investigate the roles of circRNA hsa_circ_0009096 in the regulation of HSC proliferation and hepatic fibrosis.

Methods
A cellular hepatic fibrosis model was established by treating LX-2 cells with transforming growth factor β (TGF-β1). RNaseR and actinomycin D assays were performed to detect hsa_circ_0009096 stability. Expression of hsa_circ_0009096, miR-370-3p, and target genes was detected using reverse transcription-qPCR. Direct binding of hsa_circ_0009096 to miR-370-3p was validated using dual luciferase reporter assay. Cell cycle progression and apoptosis of LX-2 cells were assessed using flow cytometry. The alpha-smooth muscle actin (α-SMA), collagen 1A1 (COL1A1), and TGF beta receptor 2 (TGFBR2) protein levels in LX-2 cells were analyzed using immunocytochemistry and western blotting.

Results
Hsa_circ_0009096 exhibited more resistance to RNase R and actinomycinD digestion than UTRN mRNA. Hsa_circ_0009096 expression increased significantly in LX-2 cells treated with TGF-β1, accompanied by elevated α-SMA and COL1A1 expression. Hsa_circ_0009096 siRNAs effectively promoted miR-370-3p and suppressed TGFBR2 expression in LX-2 cells, mediated by direct association of hsa_circ_0009096 with miR-370-3p. Hsa_circ_0009096 siRNA interfered with the cell cycle progression, promoted apoptosis, and reduced α-SMA and COL1A1 expression in LX-2 cells treated with TGF-β1. MiR-370-3p inhibitors mitigated the alterations in cell cycle progression, apoptosis, and α-SMA, COL1A1, and TGFBR2 expression in LX-2 cells caused by hsa_circ_0009096 siRNA. In conclusion, hsa_circ_0009096 promoted HSC proliferation and hepatic fibrosis during BA pathogenesis by accelerating TGFBR2 expression by sponging miR-370-3p.
Study of the Abutment Screw threads of Internal Hexagon and Morse Taper Connection Implants and their loosening after Fatigue Testing
Authors: Siliano Fernanda Marques , Bassoukou Cristine Haralambos , Oliveira Jasiel de , Sendyk Wilson Roberto , Tanaka Marcia Hiromi , Turssi Cecilia Pedroso 
Published: May 2024

Aims: To evaluate the length of the thread portion and the distance between the thread pitches of internal hexagon (IH) and morse taper (MT) connection screws and their loosening after fatigue testing.
Methodology: Ten IH and ten MT implants received abutments torqued 20 N.cm. The implant-abutment sets were subjected to fatigue by mechanical cycling. After testing the removal torque of the abutments was measured and the abutments and screws were analyzed by scanning electron microscopy.
Results: Student's t-test showed there was no significant difference between the removal torque values among the groups (p=0.609). The length of the screw thread portion of the IH connection was significantly longer than that of the MT connection (p<0.001). There was no significant difference between the groups regarding the distance between the threads of the screws. (p=0.734).
Conclusion: The thread portion of screws in the internal hexagon connection was larger than that of screws in the morse taper connection. However, the distance between thread pitches and the removal torque values under fatigue testing were similar for screws in both types of connections.
Prevalence of Work-Related Repetitive Stress Injuries amongst the Health Care Workers in Large Tertiary Care Hospital
Authors: Anupama Salam , Singh Oinam Gokulchandra , Alsubaie Mohammed Abdulmohsen , Haq Fayaz Ul , Alanazi Faisal Awadh 
Published: May 2024

Aims: To investigate the prevalence of work-related repetitive stress injuries amongst the healthcare professionals in large tertiary care hospital
Materials & Methods: The study was conducted on 42 healthcare professionals (22 males and 20 females. The participants of the age range between 18 to 65 years. A cross-sectional survey was conducted using a validated research instrument questionnaire consisting of 52 questions divided into multiple parts. Descriptive statistics were used to explain the demographic characteristics and information regarding the prevalence of work-related musculoskeletal work disorders of the respondents. This study was conducted at teaching hospital of Maharishi Markandeshwar University, Mullana, Haryana, India in different department between November, 2018 and April, 2019.
Results: A total of the 42 respondents were returned and properly filled questionnaires. Out of total 42 respondents, 5(11.9%) of the health care workers did not have any work-related musculoskeletal disorders (WRMSD). It is reported that overall 52.3% of the respondents were male and 47.7% were female. It has several strata such as four radiologist, six medical physicians/general physicians; four physiotherapists; seven dentists; nine radiographers; four laboratory technologists; eight nurses respectively. Amongst the health professional workers, dentists were the most prevalence of occurring work related musculoskeletal disorder followed by radiographer, physiotherapist, radiologist, laboratory technologist, medical physician, and nurse. However, neck pain being the most common affected body region where 5 dentists were recorded. Subsequently, neck pain account to 40.4% amongst the health care workers followed by shoulder pain 23.8%, hand pain 11.9%, lower back pain 7.2% and wrist pain 4.8%.
Conclusion: Based on our study, the finding demonstrated the top three most prevalence occurring musculoskeletal disorder amongst health professional are dentist, radiographer and physiotherapist. Larger sample size would be required in order show an empirical evidence.
Tunable Colors in Opals and Inverse Opal Photonic Crystals
Authors: Aguirre Carlos I. , Reguera Edilso , Stein Andreas 
Published: July 2010

AbstractColloidal photonic crystals and materials derived from colloidal crystals can exhibit distinct structural colors that result from incomplete photonic band gaps. Through rational materials design, the colors of such photonic crystals can be tuned reversibly by external physical and chemical stimuli. Such stimuli include solvent and dye infiltration, applied electric or magnetic fields, mechanical deformation, light irradiation, temperature changes, changes in pH, and specific molecular interactions. Reversible color changes result from alterations in lattice spacings, filling fractions, and refractive index of system components. This review article highlights the different systems and mechanisms for achieving tunable color based on opaline materials with close‐packed or non‐close‐packed structural elements and inverse opal photonic crystals. Inorganic and polymeric systems, such as hydrogels, metallopolymers, and elastomers are discussed.
Experimental investigation of flow regimes of axisymmetric and planar opposed jets
Authors: Li Wei‐Feng , Yao Tian‐Liang , Liu Hai‐Feng , Wang Fu‐Chen 
Published: July 2010

AbstractDynamic behaviors of axisymmetric and planar opposed jets have been experimentally studied at 786 < Re < 6288. The flow patterns were investigated by a smoke‐wire technique, and the smoke‐wire photos were recorded by a high‐speed camera. Different flow regimes of axisymmetric and planar opposed jets have been identified. Axisymmetric opposed jets exhibit axial quasi‐periodic oscillations, stagnation point offsets, and steady states, while planar opposed jets exhibit both horizontal instabilities and deflecting oscillations. Effects of the nozzle separation and the exit Reynolds number on the dynamic characteristics of axisymmetric and planar opposed jets have been investigated and discussed. Maps of parameter spaces describing the flow regimes of axisymmetric and planar opposed jets at various nozzle separations and exit Reynolds numbers have been presented. © 2010 American Institute of Chemical Engineers AIChE J, 2011
Hybrid thermosets from polyisocyanate/water glass/emulsifier systems: Effects of melamine‐formaldehyde resin
Authors: Castellà Núria , Grishchuk Sergiy , Karger‐Kocsis Jozsef , Schehl Martin 
Published: July 2010

AbstractMelamine‐formaldehyde resin (MF) was selected as potential reactive emulsifier for polyurea‐based thermoset resins produced from polyisocyanate/water glass (WG)/emulsifier systems. As emulsifier tricresylphosphate and/or MF served for the initial water‐in‐oil type (“water” = WG; “oil” = polyisocyanate + emulsifier) emulsions. The MF content of the systems has been varied (≤15 wt %) and its effect on the structure, mechanical, thermal and flammability properties of the final polyurea‐based thermosets studied. It was found that MF is a suitable emulsifier, which can fully replace the phosphate without negatively affecting the properties of the resulting hybrid thermosets. Moreover, hybridization with MF was often accompanied with pronounced improvements in fracture mechanical and static flexural properties. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Polystyrene/vinyl ester resin/styrene thermoplastic elastomer composites: Miscibility, morphology, and mechanical properties
Authors: Gu Jun , Lu Jiaming , Huang Xiancong , Wang Xinling , Zheng Zhen 
Published: July 2010

AbstractPolystyrene/Styrene‐Ethylene‐Propylene‐Styrene/Vinyl Ester Resin (PS/SEPS/VER) blends used as matrix of ultra high molecular weight polyethylene (UHMWPE) fiber‐reinforced composites, which included both physical crosslinking points of thermoplastic resin SEPS and chemical crosslinking network of thermosetting resin PS/VER, were prepared by solution blending and hot‐molding. Morphology and mechanical properties of the PS/SEPS/VER composites were investigated in this work. The microstructure of PS/SEPS/VER composites observed by means of scanning electron microscopy (SEM) was correlated with mechanical properties. It is worth noting that, stiffness increased sharply with the addition of VER within a certain range. Impact properties verified the structure that the physical crosslinking points of SEPS were immersed in the chemical crosslinking network of PS/VER. Dynamic mechanical analysis revealed that, incorporation of VER changed the storage modulus and loss tangent. In brief, addition of VER had improved mechanical properties, thermal stability, and fluidity of the composites during processing, indicating a successful result for preparing resin matrix material with outstanding comprehensive performances. Analog map was presented to facilitate better understanding of the special structure of PS/SEPS/VER. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Melt grafting of maleic anhydride onto polypropylene with 1‐decene as a second monomer
Authors: Lei Caihong , Li Shanliang , Chen Dahua , Wu Bo , Huang Weiliang 
Published: July 2010

AbstractThe influence of 1‐decene as the second monomer on the melt‐grafting behavior of maleic anhydride (MAH) onto polypropylene (PP) was studied with differential scanning calorimetry and Fourier transform infrared spectroscopy. We found that the value of the grafting degree increased from 0.68% for pure MAH‐g‐PP to 1.43% for the system with a 1‐decene/MAH molar ratio of 0.3, whereas the maximum value with styrene (St) as the second monomer was 0.98% under an St/MAH molar ratio of 1.0. Compared with the contribution of St/MAH‐g‐PP to the peeling strength between the PP and polyamide (PA) layer for a PP/PA laminated film, the introduction of 1‐decene/MAH‐g‐PP increased the peeling strength from 180 g/15 mm to 250 g/15 mm. 1‐Decene inhibited the chain scission behavior of PP. 1‐Decene reacted with MAH to form a 1‐decene/MAH copolymer or the Alder‐ene reaction product before the two monomers grafted onto PP. The grafting of the reactive product onto PP greatly improved the grafting degree of MAH. What is more, because of the similar chemical structures of 1‐decene and PP, the affinity of 1‐decene with PP was higher than that of St. Compared with St, the introduction of less 1‐decene led to a higher grafting degree and higher peeling strength. Therefore, we concluded that 1‐decene was more effective for improving the grafting degree of MAH onto PP. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011