bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potassium dichromate sensitivity presenting as tefillin dermatitis: A retrospective cohort study
Authors: Hilewitz Daniel , Trattner Akiva , Noyman Yehonatan , Mimouni Daniel , Snast Igor 
Published: June 2024

AbstractBackgroundTefillin are a religious article worn by Jewish men during daily prayer. Tefillin dermatitis secondary to potassium dichromate sensitivity is recognised, but data remain sparse.ObjectiveTo investigate the prevalence and clinical characteristics of tefillin dermatitis.MethodsPatients who underwent patch testing with the European baseline series in a tertiary dermatology clinic in 2009–2023 and were diagnosed with tefillin dermatitis were identified by file review and their clinical data recorded.ResultsOf 1679 consecutive male patients tested, 25 (1.49%) were diagnosed with tefillin dermatitis, accounting for 15.34% of all potassium‐dichromate‐positive patients (163/1679). Mean pre‐symptomatic duration of tefillin use was 38 ± 16.9 years, and mean follow‐up time, 3.1 ± 2.9 years. Patients presented with an eczematous rash on body areas in direct contact with the leather box or straps of the tefillin. An id reaction was noted in 32%, and sensitivity to other leather accessories, in 44%. Fourteen patients (56%) switched to chromate‐free tefillin: symptoms resolved completely in 11 (79%) and partially in 2.LimitationsRetrospective cohort design.ConclusionThis is the largest study to date of tefillin dermatitis caused by sensitivity to potassium dichromate used in leather production. Prognosis after switching to chromate‐free tefillin was good‐to‐excellent. Tefillin dermatitis may be more prevalent than previously thought.
A conversion proposal for biomass estimates in termites
Authors: Silva Israel S. , Vasconcellos Alexandre 
Published: June 2024

AbstractTermites (Isoptera) constitute a considerable fraction of the global animal biomass. Conventionally, termite dry biomass estimates (g) range between 1:3 and 1:6 of fresh biomass (g). But estimates are often based on a few species or coarse taxonomic resolution. In this study, we (1) calculated the fresh and dry mass of 15 widely distributed Neotropical termite species (three families) and (2) established the conversion ratio for dry mass, which is indispensable for biomass estimates. Workers and soldiers were sampled in their colonies and quickly weighed in the laboratory to obtain the fresh mass. Then, the individuals were placed in 80% alcohol for 5 days and weighed. Finally, the samples were dried at 60°C for 24 h and weighed again. Our results suggest an average ratio of 1:4.2 (dry‐to‐fresh mass), with a mean (±SE) conversion ratio of 0.24 ± 0.06, for estimating termite biomass at local, regional, and global scales. Moreover, our results demonstrate that values from termites preserved in alcohol could still be used to estimate biomass. Specifically, after insertion in alcohol, the termites lost 16.9%–56% of their water content, with an average of 26.5%. While this represents a source of bias in estimates using samples from biological collections, dry mass was significantly related to fresh mass ( = 0.99; dry mass = 0.000055 + 0.22 × fresh mass), and to the mass of termites in alcohol ( = 0.97; dry mass = 0.00014 + 0.26 × mass in alcohol). Applying our results to data from the literature indicates that global termite dry biomass ranges from 89 to 106 Mt.
Sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) plus glucagon‐like peptide type 1 receptor combination is more effective than SGLT2i plus dipeptidyl peptidase‐4 inhibitor combination in treating obese mice metabolic dysfunction‐associated steatotic liver disease (MASLD)
Authors: Reis‐Barbosa Pedro H. , Mandarim‐de‐Lacerda Carlos A. 
Published: June 2024

AbstractBackgroundMonotherapy to treat obesity‐associated liver insult is limited.ObjectivesIn diet‐induced obese mice showing metabolic dysfunction‐associated steatotic liver disease (MASLD), we aimed to compare the combinations of sodium‐glucose cotransporter‐2 inhibitor (SGLT2i, empagliflozin, E), dipeptidyl peptidase‐4 inhibitor (DPP4i, linagliptin, L), and glucagon‐like peptide type 1 receptor agonist (GLP1RA, dulaglutide, D).MethodsMale 3‐month‐old C57BL/6J mice were fed for 12 weeks in a control (C, n = 10) or high‐fat (HF, n = 30) diet. Then, mice were followed for three additional weeks: C, HF, HF E + L, and HF E + D (n = 10/group).ResultsHF versus C showed higher hepatic triacylglycerol (TAG, +82%), steatosis (+850%), glucose intolerance (+71%), insulin (+98%), and insulin resistance (+68%). Compared to the HF group, HF E + L showed lower glucose intolerance (−60%), insulin (−61%), insulin resistance (−46%), TAG (−61%), and steatosis (−58%), and HF E + D showed lower glucose intolerance (−71%), insulin (−58%), insulin resistance (−62%), TAG (−61%), and steatosis (−82%). The principal component analysis (PCA) placed the HF group and the HF E + D group on opposite sides, while the HF E + L group was placed between C and HF E + D.ConclusionPCA separated the groups considering the metabolism‐related genes (glucose and lipid), mitochondrial biogenesis, and steatosis. The two pharmacological combinations showed beneficial effects in treating obesity and MASLD. However, the combination of SGLT2i and GLP1RA showed more potent beneficial effects on MASLD than SGLT2i and DPP4i and, therefore, should be the recommended combination.
Long‐term effectiveness of eptinezumab in the treatment of patients with chronic migraine and medication‐overuse headache
Authors: Blumenfeld Andrew , Kudrow David , McAllister Peter , Boserup Line Pickering , Hirman Joe , Cady Roger 
Published: June 2024

AbstractObjectiveThis post hoc analysis of the PREVAIL study explored the effectiveness of eptinezumab for up to 2 years of open‐label treatment in the subgroup of patients with chronic migraine who had a confirmed diagnosis of medication‐overuse headache (MOH) at screening.BackgroundMOH is a disabling and costly secondary headache disorder characterized by increased headache frequency and/or severity with increased acute headache medication use. Eptinezumab, an anti–calcitonin gene‐related peptide monoclonal antibody, reduces headache frequency, severity, and associated disability and improves functioning and health‐related quality of life as a preventive migraine therapy; short‐term benefits in patients with concurrent MOH have also been reported.MethodsParticipants received up to eight quarterly intravenous infusions of eptinezumab 300 mg in the phase 3, single‐arm, open‐label PREVAIL study. Safety and patient‐reported outcome measures (Migraine Disability Assessment [MIDAS], 6‐item Headache Impact Test [HIT‐6], patient‐identified most bothersome symptom [PI‐MBS], Patient Global Impression of Change [PGIC], and 36‐item Short‐Form Health Survey [SF‐36]) were conducted at predefined intervals. Patients were observed up to 20 weeks after their last infusion (Week 104).ResultsA total of 49/128 (38.3%) patients enrolled in PREVAIL had an MOH diagnosis at screening. In the MOH subgroup, long‐term eptinezumab treatment was associated with reductions in headache frequency (43/49 [87.8%] patients reported ≥50% reduction in MIDAS‐derived headache days at ≥1 visit), severity (2.2‐point reduction [on a 10‐point scale]), disability (mean MIDAS total score reduction of 51.9 points), and impact (mean HIT‐6 total score reduction of 9.7 points) at Week 104. Most patients described a “much improved” or “very much improved” status by Week 48 (PI‐MBS, 31/46 [67.4%]) and Week 104 (PGIC, 31/36 [86.1%]). Health‐related quality of life improvements in the SF‐36 were also observed.ConclusionEptinezumab preventive therapy in patients with chronic migraine showed benefits that extended to the subset of patients with concomitant MOH.
Review of testing methods to inform materials selection in high‐temperature structural applications
Authors: Rossi Alicia , Hilmas Ashley , Josken Amber , Dickerson Matthew , Detwiler Kaitlin 
Published: June 2024

AbstractCareful material selection is paramount to meet the significant challenges posed by harsh environments in advanced applications. Ceramic matrix composites (CMCs) have come to the forefront of consideration for many of these applications where environmental resistance needs to be combined with structural stability at high temperatures (1200°C+). Many gaps exist in understanding how material variations pose unique material and design challenges that affect the final performance in a particular application. Thorough materials testing at relevant temperatures is required for various candidate materials to realize an analytical approach to materials selection. This review will discuss mechanical and environmental tests and their use at high temperatures including tensile tests, flexure tests, lifetime testing methods, interlaminar tests, and environmentally relevant tests. Challenges for performing these tests at high temperatures and on CMCs will be discussed. A literature review will provide examples of state‐of‐the‐art testing, and the test results from historical work and improvement opportunities will be addressed. This review aims to provide an overview of the current capabilities and practices for high‐temperature testing and recommend best practices for performing high‐temperature tests and interpreting and sharing the results and metadata with the larger community to expand the CMC material property database.
Impulsive buying in buyer–seller service encounters
Authors: Ali Fayaz , Tauni Muhammad Zubair , Butt Asad Hassan , Ali Ayaz , Yuan Jingbo 
Published: June 2024

AbstractThis research examines the impact of buyer–seller similarities (dissimilarities) in Big Five personalities—agreeableness, conscientiousness, extraversion, openness, and neuroticism—on impulsive buying in a dyadic setting. The study further analyzed how the interaction intensity and sensory stimulation mediate the effect of buyer–seller similarities (dissimilarities) on impulsive buying. The authors gathered 1020 dyad data from various beauty salons located in China to achieve research objectives. Difference score analysis was used to compute buyer–seller similarity (dissimilarity), and a variance‐based structural equation modeling technique was applied to analyze the data. The results indicate that the similarity of dyads in agreeableness and openness increases impulsive buying, while similarity in neurotic dyads decreases impulsive buying. Furthermore, interaction intensity mediates the relationships of dyads' similarities—in extraversion and openness—with impulsive buying, while buyers' sensory stimulation mediates the associations of buyer–seller dyads' similarities—in extraversion, neuroticism, and openness—with impulsive buying. Finally, this study provides several implications for marketers in the services industry.
The effectiveness of multidisciplinary weight loss interventions is associated with initial cardiorespiratory fitness in adolescents with obesity
Authors: Allali Brahim , Pereira Bruno , Fillon Alicia , Pouele Lili , Masurier Julie , Cardenoux Charlotte , Isacco Laurie , Boirie Yves , Duclos Martine , Thivel David , Julian Valérie 
Published: June 2024

SummaryBackgroundThe identification of predictive parameters of the success of multidisciplinary weight loss interventions (MWLI) appears essential to optimize obesity management. The association between baseline cardiorespiratory fitness (CRF) and changes in anthropometric parameters and body composition during MWLI remains underexplored in adolescents with obesity.ObjectivesTo assess whether baseline CRF was associated with the effectiveness of a 16‐week MWLI measured through improved body mass, body mass index (BMI) and body composition (percentage of total fat mass (FM) as the main criterion).MethodsCardiorespiratory fitness and body composition were respectively measured by peak oxygen consumption (VO2peak) during maximal exercise tests and dual‐photon x‐ray absorptiometry (DXA), before (T0) and after (T1) a 16‐week MWLI in 165 adolescents (aged 13.3 ± 1.38 years, 61.2% female, BMI 35.11 ± 5.16 kg/m2).ResultsReductions in BMI and total FM percentage between T0 and T1 were greater in subjects with a baseline VO2peak ≥ 3rd quartile compared to the first quartile (p < 0.001) and the interquartile range (p < 0.05 and p < 0.001, respectively). Baseline VO2peak and VO2 at the first ventilator threshold were positively correlated with the reductions in body mass, BMI and total and visceral FM percentages and with the increase in lean mass (LM) percentage between T0 and T1 after adjustment for age and gender (p < 0.001).ConclusionInitial CRF is associated with the success of MWLI in adolescents with obesity. Improving their aerobic fitness before starting a MWLI might be a promising strategy to optimize its benefits.
How Does the Burden of Respiratory Syncytial Virus Compare to Influenza in Spanish Adults?
Authors: Martinón‐Torres Federico , Gutierrez Clara , Cáceres Ana , Weber Karin , Torres Antoni 
Published: June 2024

ABSTRACTBackgroundRespiratory syncytial virus (RSV) and influenza infections cause significant annual morbidity and mortality worldwide in at‐risk populations. This study is aimed at assessing hospital burden and healthcare resource utilization (HRU) of RSV and influenza in adults in Spain.MethodsData were obtained from the Projected Hospitalisation Database of inpatient episodes (ages: younger adults 18–50 and 51–64 years; older adults 65–74, 75–84, and ≥ 85 years) during 2015, 2017, and 2018 in Spanish public hospitals. Incidence, mean hospitalization, and HRU assessments, including length of stay (LOS), intensive care unit (ICU) usage, and age‐standardized mortality rates, were collected and stratified by age group, with analyses focusing on the adult population (≥ 18 years old).ResultsMean hospitalization rate in the population across all years was lower in individuals with RSV versus influenza (7.2/100,000 vs. 49.7/100,000 individuals). ICU admissions and median LOS were similar by age group for both viruses. Age‐standardized mortality was 6.3/100,000 individuals and 6.1/100,000 individuals in patients with RSV and influenza, respectively, and mortality rates were similar in older adults (≥ 65 years) for both viruses.ConclusionsRSV and influenza infection were associated with considerable HRU. There is a substantial disease burden for RSV infection in older adults ≥ 65 years. While RSV hospitalization rates in adults reported here appeared lower than influenza, RSV is still underdiagnosed in the hospital setting and its incidence might be similar to, or higher than, influenza.
Late‐Season Influenza Vaccine Effectiveness Against Medically Attended Outpatient Illness, United States, December 2022–April 2023
Authors: Chung Jessie R. , Shirk Philip , Gaglani Manjusha , Mutnal Manohar B. , Nowalk Mary Patricia , Moehling Geffel Krissy , House Stacey L. , Curley Tara , Wernli Karen J. , Kiniry Erika L. , Martin Emily T. , Vaughn Ivana A. , Murugan Vel , Lim Efrem S. , Saade Elie , Faryar Kiran , Williams Olivia L. , Walter Emmanuel B. , Price Ashley M. , Barnes John R. , DaSilva Juliana , Kondor Rebecca , Ellington Sascha , Flannery Brendan 
Published: June 2024

ABSTRACTBackgroundThe 2022–23 US influenza season peaked early in fall 2022.MethodsLate‐season influenza vaccine effectiveness (VE) against outpatient, laboratory‐confirmed influenza was calculated among participants of the US Influenza VE Network using a test‐negative design.ResultsOf 2561 participants enrolled from December 12, 2022 to April 30, 2023, 91 laboratory‐confirmed influenza cases primarily had A(H1N1)pdm09 (6B.1A.5a.2a.1) or A(H3N2) (3C.2a1b.2a.2b). Overall, VE was 30% (95% confidence interval −9%, 54%); low late‐season activity precluded estimation for most subgroups.Conclusions2022–23 late‐season outpatient influenza VE was not statistically significant. Genomic characterization may improve the identification of influenza viruses that circulate postinfluenza peak.
The influence of culture on the health beliefs and health behaviours of older Vietnam‐born Australians living with chronic disease
Authors: Nguyen Thi Ngoc Minh , Saunders Rosemary , Dermody Gordana , Whitehead Lisa 
Published: June 2024

AbstractAimTo explore the health beliefs and health behaviours of older Vietnam‐born people living with chronic disease in Western Australia.DesignThis study was designed as a focused ethnography guided by the interpretative research paradigm and Leininger's Theory of Culture Care.MethodsData were collected through participant observation and interviews undertaken at participants' homes in Western Australia over 7 months in 2019. Data were analysed using Wolcott's approach for transferring qualitative data, comprising three phases: description, thematic analysis and interpretation.ResultsThis study included 12 participants. The health perspectives and practices of older Vietnam‐born Australians significantly reflected the traditional Vietnamese values. These included the stigma towards chronic disease as an inevitable consequence of ageing; self‐blame thoughts about chronic disease causations and maintained traditional dietary practices. However, some aspects of their health behaviours such as beliefs and practices in traditional medicine, Western medicine and physical exercise reflected a blended approach combining both Vietnamese‐oriented and Westernized‐orientated practices. Individual factors were also identified as contributing to chronic disease self‐care among participants.ConclusionThis study emphasizes culture played a significant role in shaping the way that older Vietnam‐born Australians believed and behaved while living with chronic conditions. However, it also indicates that culture is not a stationary concept, it evolves gradually and is socially constructed.ImplicationsA better understanding of the health beliefs and practices of older Vietnam‐born Australians is expected to contribute to the delivery of culturally safe and effective support for this population. The achievement of culturally safe care requires a systemic approach and collaboration of strategies across sectors.Patient and public contributionThis study encompassed the contribution of 12 older Vietnam‐born Australians who offered the researcher the privilege to enter their world and the staff of social care organization who opened the gate for the researcher to approach participants.
Sex hormones in COVID‐19 severity: The quest for evidence and influence mechanisms
Authors: Xiao Haiqing , Wei Jiayi , Yuan Lunzhi , Li Jiayuan , Zhang Chang , Liu Gang , Liu Xuan 
Published: June 2024

AbstractStudies have reported variable effects of sex hormones on serious diseases. Severe disease and mortality rates in COVID‐19 show marked gender differences that may be related to sex hormones. Sex hormones regulate the expression of the viral receptors ACE2 and TMPRSS2, which affect the extent of viral infection and consequently cause variable outcomes. In addition, sex hormones have complex regulatory mechanisms that affect the immune response to viruses. These hormones also affect metabolism, leading to visceral obesity and severe disease can result from complications such as thrombosis. This review presents the latest researches on the regulatory functions of hormones in viral receptors, immune responses, complications as well as their role in COVID‐19 progression. It also discusses the therapeutic possibilities of these hormones by reviewing the recent findings of clinical and assay studies.
Evaluation of volatiles from ethnobotanical plants as attractants for the honey bee swarms in Kenya
Authors: Ochola John Bwire , Nganso Beatrice Tchuidjang , Subramanian Sevgan , Nkoba Kiatoko 
Published: June 2024

AbstractApiculture provides better livelihoods for about 144,000 men, women and youth in Kenya. However, various challenges and barriers are available that prevent the industry from flourishing. One of these challenges is the low hive colonization rate reported by Kenyan beekeepers, who mainly depend on swarm catching to increase colony numbers within their apiaries. Many different traditional plants are used to attract bee swarms, although they have not been tested and compared scientifically with the most used and cost‐effective bait in Africa, the beeswax, for improving swarm catches. To fill this knowledge gap, an ethnobotanical survey was carried out in Kenya to gain an in‐depth understanding of traditional apicultural practices used for hive baiting to attract swarms. Additionally, the volatile composition of traditional plants used as swarm lures was examined using gas chromatography–mass spectrometry (GC–MS), and their effectiveness in catching swarms was evaluated in comparison to beeswax in the field. The survey results revealed that Ocimum kilimandscharicum, Cymbopogon nardus and Elaeodendron buchananii are the three commonly used traditional plants for baiting, chosen based on their aroma, abundance, ease of processing and durability. Notably, the volatiles emitted by O. kilimandscharicum plus beeswax attracted significantly two and half‐fold more bee swarms than the control (beeswax alone), whereas those of E. buchananii were the least attractive and similar to those of the control. These discrepancies may be partly due to the presence of small amounts of geraniol and citral in the essential oils of O. kilimandscharicum, which are characteristic compounds of the Nasonov gland pheromone from workers honey bees known to attract bee swarms. Overall, our findings suggest that adding O. kilimandscharicum to beeswax may significantly enhance bee swarm catches in the field.
Correlation between depression scores and serum NF‐ĸB/NLRP3 axis, biotinidase, and HMGB1 after treatment with isotretinoin in patients with acne vulgaris
Authors: Binsaleh Ammena Y. , Ali Lahin Saad , Bahaa Mostafa M. , Elmasry Thanaa A. , Negm Walaa A. , Hamouda Amir O. , Salahuddin Muhammed M. , Wahsh Eman , El‐samongy Marwa Ahmed , Alsubaie Nawal , El‐Khateeb Eman , Yasser Mohamed , Eltantawy Nashwa 
Published: June 2024

AbstractBackgroundAcne vulgaris (AV) is an inflammatory skin disorder leading to scars and discomfort, its intensity has major psychological consequences such as depression.AimTo investigate the effect of isotretinoin (ISO) on NF‐κB/NLRP3, biotinidase, and HMGB and correlation with depression.Patients and MethodsThis was a case–control study that involved two groups. Group 1 is 20 healthy control, and group 2 is 20 patients diagnosed with AV according to Global Acne Grading System (GAGS) and received 20 mg ISO for 2 months. Before and after therapy, the Hamilton Depression Rating Scale (HDRS) was applied to assess each participant's level of depression. Nuclear factor kappa B (NF‐ĸB), biotinidase, high mobility group box protein (HMGB1), nucleotide‐binding domain, leucine‐rich–containing family, and pyrin domain–containing‐3 (NLRP–3) were measured in serum samples.ResultsThere was no significant difference in all measured markers of healthy group before and after 2 months. Regarding group 2, there was a statistically significant decrease in all measured markers after 2 months of treatment and significant correlations between GAGS, NF‐ĸB, HMGB1, NLRP3, biotinidase, and depression score.ConclusionIncreased GAGS, HMGB1, NLRP3, and biotinidase were associated with depression severity in AV patients and ISO treatment significantly reduced these parameters and reduced depressive symptoms.