bluuebunny/crossref_metadata_2025_split huggingface dataset:
Néologie et description linguistique pour le TAL
Authors: Cartier Emmanuel 
Published: February 2012

Dans cet article, nous présentons un travail développé au Laboratoire LDI (CNRS UMR 7187) depuis cinq ans et qui vise à intégrer le travail sur la néologie dans les langues au travers d’une plateforme dont le cœur est un dictionnaire de langue. Cette plateforme vise à décrire les mots et séquences signifiantes des langues, tout en permettant en amont, de rester en contact permanent avec les discours, au travers de procédures de repérage des mots et sens nouveaux ; en aval, de suivre statistiquement la vie des mots et des sens au travers de procédures informatiques. La néologie, dans ce cadre, est un élément pivot du système car un dictionnaire se doit de rendre compte de la vie des sens et des mots, en incluant les mots nouveaux dès qu’ils entrent dans l’usage tout en gérant les mots qui tombent en désuétude. Cet article se compose de trois parties : la première partie présentera l’architecture générale du prototype informatique ; la seconde, le modèle de stockage des néologismes ; la dernière, les procédures de suivi de la vie des néologismes initialement repérés. La partie consacrée au repérage des mots nouveaux est prise en charge dans un autre article de ce numéro.
L'adaptation morphologique des emprunts néologiques : en quoi est-elle précieuse ?
Authors: Anastassiadis-Syméonidis Anna , Nikolaou Georgia 
Published: February 2012

Notre recherche nous a permis de constater que l’adaptation morphologique des emprunts néologiques permet l’étude approfondie du système morphologique de la L1 et plus spécialement de sa dynamique, exprimée par ses structures prototypiques, fréquentes et disponibles. En effet, sur un corpus de 1 200 unités lexicales qui sont des emprunts néologiques du grec moderne (GM) au français et à l’anglo-américain, en examinant l’assignation du genre aux 331 substantifs, nous avons trouvé que l’application de quatre règles, régies par l’analogie sémantique, morpho-phonologique et interlinguistique, est en conformité avec les structures prototypiques, fréquentes et disponibles du GM. De même, en ce qui concerne leur adaptation au système flexionnel du GM, les emprunts néologiques montrent une prédilection à se conformer aux classes flexionnelles prototypiques, fréquentes et disponibles du GM.
Approches générationnelles du politique
Authors: Cartier Marie , Spire Alexis 
Published: February 2012

Résumé L’enjeu de ce dossier est de revisiter ce lieu commun de la science politique qu’est la notion de génération, pour l’enrichir des avancées récentes des autres sciences sociales. Il s’appuie sur une définition sociologique de la notion de génération inspirée de Karl Mannheim. Pour qu’une génération au sens démographique de cohortes d’âge proches, forme une génération au sens sociologique, il faut non seulement une participation aux mêmes événements et aux mêmes expériences dans les années de formation, mais surtout que celle-ci intervienne dans un « même cadre de vie historico-culturel ». En partant des institutions politiques concrètes et de leurs cohortes plutôt que des événements repérés comme tels par les médias ou les discours dominants, ce dossier explore la socialisation générationnelle de populations parfois peu visibles. Il invite à étudier derrière les prétendus « conflits de génération » le travail proprement politique (de représentation, d’unification, de mobilisation) qui façonne les appartenances et les différends générationnels.
L'engagement des enseignants du secondaire à l'épreuve des générations
Authors: Llobet Aurélie 
Published: February 2012

Résumé Sur la base d’une enquête ethnographique, cet article analyse l’évolution de l’engagement des professeurs de l’enseignement secondaire public à l’aune des transformations du métier et de l’institution scolaire. En confrontant les conditions de socialisation professionnelle et les parcours biographiques, il met en lumière trois générations. Plus qu’une opposition entre « vieux » et « jeunes » professeurs accentuant le schème de la dépolitisation, cette analyse montre que les manières de s’investir dans le métier évoluent au cours des carrières professionnelles et remodèlent le sens de l’engagement dans le métier. Malgré une distanciation par rapport aux organisations syndicales, les professeurs font converger pratiques professionnelles et politiques, et reproduisent ainsi le potentiel protestataire des enseignants du secondaire.
Le discours aigre-doux de la controverse scientifique : évolution de la rhétorique des confrontations académiques
Authors: Salager-Meyer Françoise 
Published: February 2012

Afin de déterminer l'évolution qualitative et quantitative des références critiques (rCr) et non critiques (rNCr) dans le discours médical du XIXe et du XXe siècle écrit en anglais, nous avons analysé un corpus de 90 articles médicaux publiés entre 1810 et 1995. Les résultats quantitatifs globaux indiquent que les rNCr sont significativement plus fréquentes que les rCr (p=.0001) mais que, lorsque le corpus est analysé de façon diachronique, celui-ci peut être divisé en deux blocs très distincts : A (1810-1929) et B (1930-1995). La proportion rNCr/rCr reste constante pendant les 120 premières années étudiées, mais change radicalement à partir des années 1930. Nos données qualitatives montrent que les rCr du XIXe siècle sont formulées d'une façon beaucoup plus directe, personnelle et « responsable » que celles du XXe siècle. L'évolution constatée du ton des rCr reflète l'évolution d'une médecine individuelle et anecdotique vers une médecine professionnelle et compétitive, où les scientifiques sentent le besoin impérieux de « sauver leur propre face » ainsi que celle de leurs opposants.
Is methicillin-resistant Staphylococcus aureus involved in community acquired skin and soft tissue infections?
Authors: Phakade RS , Nataraj G , Kuyare SK , Khopkar US , Mehta PR 
Published: February 2012

Background:
To improve the empiric antimicrobial therapy of community-acquired (CA) skin and soft tissue infections (SSTIs), it is necessary to generate data on the current spectrum and susceptibility profile of associated bacteria. CA methicillin-resistant Staphylococcus aureus (CA MRSA) is increasingly being reported in SSTIs in India and globally.

Aims:
The present study was undertaken to determine the bacterial profile of CA-SSTIs, to know the contribution of MRSA in these infections, to determine inducible clindamycin resistance in S. aureus and to compare the resistance patterns of isolates from hospital-acquired (HA) SSTIs. Materials and Methods: Eight hundred and twenty patients with CA SSTIs were prospectively studied. Pus samples were cultured and antimicrobial susceptibility pattern determined. Inducible clindamycin resistance was detected by D-test. Laboratory records were analyzed retrospectively to generate data on HA SSTIs.

Results:
619 isolates were recovered in CA-SSTIs, of which S. aureus (73%) and Streptococci (12%) were the most common. Pseudomonas aeruginosa (28%) and Acinetobacter spp (18%) were the predominant HA-SSTI pathogens. Susceptibility of CA S. aureus to antibiotics tested was, penicillin (6%), co-trimoxazole (20%), ciprofloxacin (37%), cefazolin (100%), erythromycin (84%), clindamycin (97%), gentamicin (94%) and fusidic acid (95%). No MRSA was found in CA SSTIs whereas 45% of HA S. aureus strains were methicillin-resistant. HA strains demonstrated significantly higher resistance as compared to their CA counterparts (P<0.001). D test was positive in 22% of CA S. aureus tested.

Conclusions:
In CA SSTIs, methicillin-susceptible S. aureus is the predominant pathogen. Penicillinase-resistant penicillins, clindamycin and erythromycin in that order can be used as suitable antimicrobials for empiric therapy. D test should be carried out routinely. No CA MRSA was detected in the present series.
Dedicated Cone-beam Breast Computed Tomography and Diagnostic Mammography: Comparison of Radiation Dose, Patient Comfort, And Qualitative Review of Imaging Findings in BI-RADS 4 and 5 Lesions
Authors: O’Connell Avice M. , Kawakyu-O’Connor Daniel 
Published: February 2012

Objective:This pilot study was undertaken to compare radiation dose, relative visibility/conspicuity of biopsy-proven lesions, and relative patient comfort in diagnostic mammography and dedicated cone-beam breast computed tomography (CBBCT) in Breast Imaging-Reporting and Data System (BI-RADS)®4 or 5 lesions.Materials and Methods:Thirty-six consecutive patients (37 breasts) with abnormal mammographic and/or ultrasound categorized as BI-RADS®4 or 5 lesions were evaluated with CBBCT prior to biopsy. Administered radiation dose was calculated for each modality. Mammograms and CBBCT images were compared side-by-side and lesion visibility/conspicuity was qualitatively scored. Histopathology of lesions was reviewed. Patients were administered a survey for qualitative evaluation of comfort between the two modalities.Results:CBBCT dose was similar to or less than diagnostic mammography, with a mean dose of 9.4 mGy (±3.1 SD) for CBBCT vs. 16.9 mGy (±6.9 SD) for diagnostic mammography in a total of 37 imaged breasts (P<0.001). Thirty-three of 34 mammographic lesions were scored as equally or better visualized in CBBCT relative to diagnostic mammography. Characterization of high-risk lesions was excellent. Patients reported greater comfort in CBBCT imaging relative to mammography.Conclusion:Our experience of side-by-side comparison of CBBCT and diagnostic mammography in BI-RADS®4 and 5 breast lesions demonstrated a high degree of correlation between the two modalities across a variety of lesion types. Owing to favorable radiation dose profile, excellent visualization of lesions, and qualitative benefits including improved patient comfort, excellent field-of-view, and more anatomical evaluation of lesion margins, CBBCT offers a promising modality for diagnostic evaluation of breast lesions.
ZINC OXIDE VERSUS MAGNESIUM OXIDE REVISITED. PART 1
Authors: Guzmán Manuel , Vega Berta , Agulló Núria , Giese Ulrich , Borrós Salvador 
Published: February 2012

Abstract
Zinc oxide is a widely used compound in the rubber industry due to the excellent properties that it shows as activator, and consequently, its role in the mechanism of accelerated sulfur vulcanization has been extensively studied. Due to the increased concern about its environmental effects, several research studies have been carried out in order to substitute it with different metal oxides such us MgO. The effect of the activator system in order to minimize the environmental impact of the rubber goods has been explored. The work developed is presented in two parts. In Part 1, the influence of different mixtures of ZnO and MgO on the vulcanization of natural rubber has been investigated. In Part 2, model compound vulcanization has been used to study the role of MgO on the mechanism to gain a better understanding of the differences shown in Part 1.
α‐Arylation of Esters Catalyzed by thePd(I) Dimer [P(t‐Bu)3Pd(μ‐Br)]2
Authors: Huang David S. , DeLuca Ryan J. , Hartwig John. F. 
Published: February 2012

AbstractDicyclohexylaminen‐ButyllithiumMethyl isobutyrate3‐BromoanisoleDi‐μ ‐bromobis(tri‐tert‐butylphosphine)dipalladiumMethyl 2‐(3‐methoxyphenyl)‐2‐methylpropanoate
The Preparation of Amides by Copper‐Mediated Oxidative Coupling of Aldehydes and Amine Hydrochloride Salts
Authors: Giguère‐Bisson Maxime , Yoo Woo‐Jin , Li. Chao‐Jun 
Published: February 2012

Abstract

L‐Valine methyl ester hydrochloride

Silver iodate

Calcium carbonate

tert
‐Butyl hydroperoxide

Benzaldehyde

(
S
)‐Methyl‐2‐benzamido‐3‐methylbutanoate
The Preparation of Indazoles Via Metal Free IntramolecularElectrophilic Amination of 2‐Aminophenyl Ketoximes
Authors: M. Counceller Carla , C. Eichman Chad , C. Wray Brenda , R. Welin Eric , P. Stambuli James 
Published: February 2012

Abstract

2’‐Aminoacetophenone

Hydroxylamine hydrochloride

Triethylamine

Methanesulfonyl chloride

3‐Methyl‐1
H
‐indazole

(
E
)‐1‐(2‐Aminophenyl)ethanone oxime
Synthesis of
Et
2
SBr
•
Sb
CI
5
Br
and Its Use in Biomimetic Brominative Polyene Cyclizations
Authors: Snyder Scott A , Treitler Daniel S 
Published: February 2012

Abstract

Bromine

Diethyl sulfide

Bromodiethylsulfonium Bromopentachloroantimonate

Antimony pentachloride

Geraniol

Diethyl chlorophosphate

Homogeranylbenzene

Benzylmagnesium chloride

Phenanthrene
Synthesis of (+)‐
B
‐Allyldiisopinocampheylborane and its Reaction with Aldehydes
Authors: Sun Huikai , Roush William R 
Published: February 2012

Abstract

(+)‐B‐Allyldiisopinocampheylborane ((+)‐(Ipc)2B(allyl) or (
l
Ipc)2B(allyl))

(+)‐B‐Methoxydiisopinocampheylborane ((+)‐(Ipc)
2
BOMe)

Allylmagnesium bromide

(
R
)‐3‐(
t
‐Butyldiphenylsilyloxy)‐2‐methylpropanal

Hydrogen peroxide

(1
R
,2
R
,3
R
,5
S
)‐2,6,6‐Trimethylbicyclo[ 3.1.1 ]heptan‐3‐ol

(2
R
,3
R
)‐1‐(
t
‐Butyldiphenylsilyloxy)‐2‐methylhex‐5‐en‐3‐ol

(2
R
,3
S
)‐1‐(
t
‐Butyldiphenylsilyloxy)‐2‐methylhex‐5‐en‐3‐ol

(2
R
,3
R
)‐1‐(
t
‐Butyldiphenylsilyloxy)‐2‐methyl‐5‐methyleneoct‐7‐en‐3‐ol

(1
S
,2
S
,3
S
,5
R
)‐3‐hydroperoxy‐2,6,6‐trimethylbicyclo[3.1.1]heptane
The Preparation of Cyclohept‐4‐Enones by Rhodium‐Catalyzed Intermolecular[5+2] Cycloaddition
Authors: Wender Paul A. , Lesser Adam B. , Sirois Lauren E. 
Published: February 2012

Abstract

Chlorodicarbonylrhodium dimer

N
‐Propargylphthalimide

1,2‐Dichloroethane

1‐(2‐Methoxyethoxy)‐1‐vinylcyclopropane
Organocatalytic Enantioselective Synthesis of Bicyclic β‐Lactones Via Nucleophile‐Catalyzed Aldol‐Lactonization (NCAL)
Authors: Nguyen Henry , Oh Seongho , Henry‐Riyad Huda , Sepulveda Diana , Romo Daniel 
Published: February 2012

Abstract(1,4‐Dioxaspiro[4.5]dec‐7‐en‐8‐yloxy)trimethylsilane1,4‐Cyclohexanedione mono‐ethylene ketalTrimethylsilyl chlorideTriethylamine3‐(2‐(2‐Oxoethyl)‐1,3‐dioxolan‐2‐yl) propanoic acid 360794‐17‐8TriphenylphosphineN‐Methyl‐2‐chloropyridinium trifluoromethane sulfonate Pyridinium, 2‐chloro‐1‐methyl‐, 1,1,1‐trifluoromethanesulfonate (1:1)2‐ChloropyridineMethyl trifluoromethanesulfonateQuinidineDiisopropylethylamine
Preparation of Horner‐Wadsworth‐Emmons Reagent: Methyl 2‐Benzyloxycarbonylamino‐2‐(Dimethoxy‐ Phosphinyl)Acetate
Authors: Azuma Hiroki , Okano Kentaro , Fukuyama Tohru , Tokuyama Hidetoshi 
Published: February 2012

Abstract

Benzyl carbamate

Glyoxylic acid monohydrate

Sulfuric acid

Phosphorous trichloride

Trimethylphosphite
Preparation of
A
Trifluoromethyl Transfer Agent: 1‐Trifluoromethyl‐1,3‐Dihydro‐3,3‐Dimethyl‐1,2‐Benziodoxole
Authors: Eisenberger Patrick , Kieltsch Iris , Koller Raffael , Stanek Kyrill , Stanek Kyrill , Togni Antonio 
Published: February 2012

Abstract

2‐(2‐Iodophenyl)propan‐2‐ol

1‐Chloro‐1,3‐dihydro‐3,3‐dimethyl‐1,2‐benziodoxole

1‐Trifluoromethyl‐1,3‐dihydro‐3,3‐dimethyl‐1,2‐benziodoxole

Iodomethane

Methyl 2‐iodobenzoate

Tert
‐butyl hypochlorite

(Trifluoromethyl)trimethylsilane

Tetrabutylammonium difluorotriphenylsilicate(IV)

2‐Iodobenzoic acid

Sodium (meta)periodate

1‐Hydroxy‐1,2‐benziodoxol‐3‐(1
H
)‐one

Acetic anhydride

1‐Acetoxy‐1,2‐benziodoxol‐3‐(1
H
)‐one

Cesium fluoride

1‐(Trifluoromethyl)‐1,2‐benziodoxol‐3(1
H
)‐one

Ethyl (
R
)‐2‐amino‐3‐mercaptopropanoate hydrochloride
Discussion addendum for: 4‐Methoxy‐4‐Nitrophenyl. Recent Advances in the Stille Biaryl Coupling Reaction and Applications in Complex Natural Products Synthesis
Authors: Williams Robert M. 
Published: February 2012

Abstract4‐methoxy‐4’‐nitrophenyltri‐t‐butyl phosphinecopper(I) saltschloropeptinhimastatin
Discussion Addendum for: Palladium‐Catalyzed Reaction of 1‐Alkenylboronates with Vinylic Halides: (1Z,3E)‐1‐Phenyl‐1,3‐Octadiene
Authors: Miyaura Norio 
Published: February 2012

AbstractDisiamylboranedicyclohexylborane9‐borabicyclo[3.3.1]nonanecatecholboranedihaloborane(1Z,3E)‐1‐phenyl‐1,3‐octadiene
Discussion Addendum for: Palladium(0)‐Catalyzed Reaction of 9‐Alkyl‐9‐Borabicyclo[3.3.1]Nonane with 1‐Bromo‐1‐Phenylthioethene: 4‐(3‐Cyclohexenyl)‐2‐Phenylthio‐1‐Butene
Authors: Miyaura Norio 
Published: February 2012

Abstract

9‐alkyl‐9‐borabicyclo[3.3.1]nonane

1‐bromo‐1‐phenylthioethene

sodium methoxide

methylboroxine

arene diazonium salts
Gram Scale Catalytic Asymmetric Aziridination: Preparation of (2

R

,3

R

)‐Ethyl 1‐Benzhydryl‐3‐(4‐Bromophenyl)Aziridine 2‐Carboxylate
Authors: Desai Aman A. , Morán‐Ramallal Roberto , Wulff William D. 
Published: February 2012

Abstract

N
‐(4‐Bromobenzylidene)‐1,1‐diphenylmethanamine

4‐Bromobenzaldehyde

Aminodiphenylmethane

Triphenyl borate

(
S
)‐VANOL

(2
R
,3
R
)‐Ethyl 1‐benzhydryl‐3‐(4‐bromophenyl)aziridine‐2‐carboxylate

Ethyl diazoacetate
Discussion Addendum for: Palladium‐Catalyzed Reduction of Vinyl Trifluoromethanesulfonates to Alkenes: Cholesta‐3,5‐Diene
Authors: Cacchi Sandro , Morera Enrico , Ortar Giorgio 
Published: February 2012

Abstractcholesta‐3,5‐diene2,6‐lutidine1,1’‐bis(diphenylphosphino)ferrocene1,3‐bis(diphenylphosphino)propane1,3‐bis(diphenylphosphino)butanePinacolborane3‐methyl‐1‐azatricyclo[5.2.1.0]decane(–)‐Galantamine
An Economical Synthesis of 4‐Trimethylsilyl‐2‐Butyn‐1‐
OL
Authors: Wein Alexander N. , Tong Rongbiao , McDonald Frank E. 
Published: February 2012

Abstract

2‐Butyn‐1‐ol

n
‐Butyllithium

tert
‐Butyllithium

Chlorotrimethylsilane
Silver‐Catalyzed Rearrangement of Propargylic Sulfinates: Synthesis of Allenic Sulfones
Authors: Harmata Michael , Cai Zhengxin , Huang Chaofeng 
Published: February 2012

Abstract

But‐3‐yn‐2‐yl 4‐Methylbenzenesulfinate

Tosyl chloride

Triethylamine

Triphenylphosphine

1‐(Buta‐1,2‐dien‐1‐ylsulfonyl)‐4‐methylbenzene

Silver hexafluoroantimonate
(
S
a
,
S
)‐
N
‐[2′‐(4‐Methylphenylsulfonamido)‐1,1′‐Binaphthyl‐2‐Yl]Pyrrolidine‐2‐Carboxamide: An Organocatalyst for the Direct Aldol Reaction
Authors: Vizóquez Santiago F. , Guillena Gabriela , Nájera Carmen , Bradshaw Ben , Etxebarria‐Jardi Gorka , Bonjoch Josep 
Published: February 2012

Abstract

(

S
a

)‐(‐)‐1,1′‐Binaphthyl‐2,2′‐diamine

p
‐Toluenesulfonyl chloride

Pyridine

N
‐(
tert‐
Butoxycarbonyl)‐
L
‐proline

Ethyl chloroformate

Triethylamine

Trifluoroacetic acid
Tandem Nucleophilic Addition / Fragmentation of Vinylogous Acyl Triflates: 2‐Methyl‐2‐(1‐Oxo‐5‐Heptynyl)‐1,3‐Dithiane
Authors: Lisboa Marilda P. , Hoang Tung T. , Dudley Gregory B. 
Published: February 2012

Abstract

2‐Methyl‐2‐(1‐oxo‐5‐heptynyl)‐1,3‐dithiane
2‐Methyl‐1,3‐dithiane
n
‐Butyllithium
2‐Methyl‐3‐trifluoromethansulfonyloxy‐cyclohex‐2‐en‐1‐one
2‐Methyl‐1,3‐cyclohexanedione

Trifluoromethanesulfonic anhydride
Synthesis and Diastereoselective Aldol Reactions of a Thiazolidinethione Chiral Auxiliary
Authors: Crimmins Michael T. , Christie Hamish S. , Hughes Colin O. 
Published: February 2012

Abstract

(
S
)‐1‐(4‐Benzyl‐2‐thioxothiazolidin‐3‐yl)propan‐1‐one
(2
S
, 3
R
)‐3‐Hydroxy‐1‐[(4
S
)‐4‐benzyl‐2‐thioxo‐thiazolidin‐3‐yl]‐2,4‐

dimethyl‐pentan‐1‐one
(2
R
, 3
S
)‐3‐Hydroxy‐1‐[(4
S
)‐4‐benzyl‐2‐thioxo‐thiazolidin‐3‐yl]‐2,4‐

dimethyl‐pentan‐1‐one
(
S
)‐Phenylalaninol

Carbon disulfide

Propionyl chloride

Pyridine
2‐Thiazolidinethione, 4‐(phenylmethyl)‐, (4
S
)‐
N
‐Methyl‐2‐pyrrolidone
(–)‐Sparteine

Isobutyraldehyde

Titanium tetrachloride
Ligand‐Free Copper(
II
) Oxide Nanoparticles Catalyzed Synthesis of Substituted Benzoxazoles
Authors: Saha Prasenjit , Ali Md Ashif , Punniyamurthy Tharmalingam 
Published: February 2012

Abstract

2‐Phenylbenzoxazole
N‐
2‐Bromophenylbenzamide
2‐Bromoaniline

Benzoyl chloride

Cesium carbonate

Copper(II) oxide nanoparticles
A sigma point‐based resampling algorithm in particle filter
Authors: Tang Xu , Huang Jian , Zhou Jian , Wei Ping 
Published: February 2012

SUMMARYWe propose a novel resampling algorithm to deal with the sample impoverishment problem of particle filter. The algorithm introduces sigma points into the generic resampling procedure to enrich the representation of the posterior distribution. Compared with other relevant resampling algorithms, such as the exquisite resampling algorithm reported recently, our algorithm has shown an improved estimation performance and reduced computational complexity in the simulation of two different nonlinear systems. Copyright © 2012 John Wiley & Sons, Ltd.
Reversal of antithrombotic agents
Authors: Bauer Kenneth A. 
Published: February 2012

AbstractAnticoagulants are the mainstay of therapy for thromboembolic diseases. In addition to the more traditional agents, new oral anticoagulants, including dabigatran etexilate, rivaroxaban, and apixaban, have been shown to be effective across several indications. Bleeding is a serious complication associated with any anticoagulant, but many of the traditional parenteral and new oral agents do not currently have specific antidotes. This review describes available and future options for the reversal of the effects of anticoagulants, in particular the new oral agents and discusses current management strategies for bleeding events in clinical practice. Am. J. Hematol. 2012. © 2012 Wiley Periodicals, Inc.
A phenotype map for 14q32.3 terminal deletions
Authors: Engels Hartmut , Schüler Herdit M. , Zink Alexander M. , Wohlleber Eva , Brockschmidt Antje , Hoischen Alexander , Drechsler Matthias , Lee Jennifer A. , Ludwig Kerstin U. , Kubisch Christian , Schwanitz Gesa , Weber Ruthild G. , Leube Barbara , Hennekam Raoul C. M. , Rudnik‐Schöneborn Sabine , Kreiß‐Nachtsheim Martina , Reutter Heiko 
Published: February 2012

AbstractDetailed molecular‐cytogenetic studies combined with thorough clinical characterization are needed to establish genotype–phenotype correlations for specific chromosome deletion syndromes. Although many patients with subtelomeric deletions have been reported, the phenotype maps for many of the corresponding syndromes, including the terminal deletion 14q syndrome, are only slowly emerging. Here, we report on five patients with terminal partial monosomy of 14q32.3 and characteristic features of terminal deletion 14q syndrome. Four of the patients carry de novo terminal deletions of 14q, three of which have not yet been reported. One patient carries an unbalanced translocation der(14)t(9;14)(q34.3;q32.3). Minimum deletion sizes as determined by molecular karyotyping and FISH are 5.82, 5.56, 4.17, 3.54, and 3.29 Mb, respectively. Based on our findings and a comprehensive review of the literature, we refine the phenotype map for typical clinical findings of the terminal deletion 14q syndrome (i.e., intellectual disability/developmental delay, muscular hypotonia, postnatal growth retardation, microcephaly, congenital heart defects, genitourinary malformations, ocular coloboma, and several dysmorphic signs). Combining this phenotype map with benign copy‐number variation data available from the Database of Genomic Variants, we propose a small region critical for certain features of the terminal deletion 14q syndrome which contains only seven RefSeq genes. © 2012 Wiley Periodicals, Inc.
Discretized thermal Green's functions
Authors: Granath M. , Sabashvili A. , Strand H.U.R. , Östlund S. 
Published: February 2012

AbstractWe present a spectral weight conserving formalism for Fermionic thermal Green's functions that are discretized in imaginary time τ and thus periodic in imaginary (“Matsubara”) frequency i ωn. The formalism requires a generalization of the Dyson equation G (G0, Σ) and the Baym‐Kadanoff‐Luttinger‐Ward functional for the free energy β Ω = Γ (G). A conformal transformation is used to analytically continue the periodized Matsubara Green's function to real frequencies in a way that conserves the discontinuity at t = 0 of the corresponding real‐time Green's function. This allows numerical Green's function calculations of very high precision and it appears to give a well controlled convergent approximation in the τ discretization. The formalism is tested on dynamical mean field theory calculations of the paramagnetic Hubbard model.