bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gratitude and suicidal ideation and suicide attempts among Chinese Adolescents: Direct, mediated, and moderated effects
Authors: Li Dongping , Zhang Wei , Li Xian , Li Nini , Ye Baojuan 
Published: July 2011

ABSTRACTIn a sample of 1252 Chinese adolescents (mean age = 15.00 years), this study examined the direct relations between gratitude and adolescents’ suicidal ideation and suicide attempts. This study also examined indirect relations between gratitude and suicidal ideation and suicide attempts via two self‐system beliefs—coping efficacy and self‐esteem. Finally, this study examined the extent to which stressful life events moderated the direct and indirect relations between gratitude and suicidal ideation and suicide attempts. The odds of suicidal ideation and suicide attempts were lower among adolescents who scored higher on gratitude, after controlling for demographic variables. Self‐esteem mediated the relations between gratitude and suicidal ideation and suicide attempts, while the mediating role of coping efficacy was not significant. Moreover, stressful life events moderated the mediated path through self‐esteem. This indirect effect was stronger for adolescents low on stressful life events than that for those high on stressful life events. This study discusses the theoretical and practical implications of these findings.
Trajectories of global self‐esteem development during adolescence
Authors: Birkeland Marianne Skogbrott , Melkevik Ole , Holsen Ingrid , Wold Bente 
Published: July 2011

ABSTRACTBased on data from a 17‐year longitudinal study of 1083 adolescents, from the ages of 13 to 30 years, the average development of self‐reported global self‐esteem was found to be high and stable during adolescence. However, there is considerable inter‐individual variance in baseline and development of global self‐esteem. This study used latent growth mixture modelling to characterize three trajectory classes of global self esteem between ages 14 and 23 years: consistently high, chronically low, and U‐shaped.The respondents in three classes showed statistically significant different levels of life satisfaction, depressive mood, somatic complaints and insomnia at age 30. Attempts to predict trajectories from age 13 were only partially successful, with body image, relations with parents and frequency of physical activity as the significant predictors.
Ricci flow of conformally compact metrics
Authors: Bahuaud Eric 
Published: July 2011

In this paper we prove that given a smoothly conformally compact asymptotically hyperbolic metric there is a short-time solution to the Ricci flow that remains smoothly conformally compact and asymptotically hyperbolic. We adapt recent results of Schnürer, Schulze and Simon to prove a stability result for conformally compact Einstein metrics sufficiently close to the hyperbolic metric.

Résumé
Lʼobjectif de cet article est de démontrer lʼexistence dʼune solution en temps court du flot de Ricci dans la classe de métriques régulières, conformément compactes et asymptotiquement hyperboliques. Nous appliquons ensuite les résultats de Schnürer, Schulze et Simon pour prouver la stabilité des métriques dʼEinstein conformément compactes suffisamment proches de la métrique hyperbolique.
Risk factors for very preterm delivery and delivery of very‐small‐for‐gestational‐age infants among HIV‐exposed and HIV‐unexposed infants in Botswana
Authors: Parekh Natasha , Ribaudo Heather , Souda Sajini , Chen Jennifer , Mmalane Mompati , Powis Kathleen , Essex Max , Makhema Joseph , Shapiro Roger L. 
Published: July 2011

AbstractObjectiveTo evaluate risk factors for very preterm delivery (VPTD) and very‐small‐for‐gestational‐age (VSGA) births in a country with a high HIV prevalence.MethodsObstetric records at 6 hospitals across Botswana were reviewed at delivery; VPTD was defined as birth before 32 weeks of pregnancy and VSGA as birth weight below the 3rd percentile for Botswana‐specific norms.ResultsOf 16 219 live births born after 26 weeks of pregnancy, 701 (4.3%) were delivered very preterm and 607 (3.7%) were VSGA; 4347 (28.4%) were documented as HIV‐exposed. In a multivariable analysis, HIV infection and hypertension during pregnancy were associated with a VPTD (adjusted odds ratio [AOR]: HIV 1.65, hypertension 1.75) and a VSGA birth (AOR: HIV infection 1.90, hypertension 3.44). Among HIV‐infected women, the continuation of highly active antiretroviral therapy (HAART) from before conception was associated with a VSGA birth (AOR 1.75) but not with a VPTD (AOR 0.78). In a secondary analysis, HAART continuation was associated with hypertension during pregnancy (AOR 1.34).ConclusionHypertension and HIV infection were risk factors for a VPTD and a VSGA birth. Continuation of HAART from before conception was associated with a VSGA birth but not with a VPTD.
Sleep quality based on the use of different sanitary pads during menstruation
Authors: Hachul Helena , Andersen Monica L. , Tufik Sergio 
Published: July 2011

AbstractObjectiveTo evaluate sleep quality among women using 2 different types of sanitary pad.MethodsSeventeen women (18–40 years) with menstrual cycles of 28–30 days and self‐reported moderate‐to‐intense menstrual flow were enrolled in a crossover study from March to August 2009 in Sao Paulo, Brazil. Sleep assessments were made by polysomnography and by means of validated questionnaires. The first evaluation of sleep (control condition) was performed during the follicular phase (7–10th day of cycle). There were subsequent evaluations during the 2nd and 3rd day of the menstrual period, and a different type of absorbent pad (A or B) was used on each day. The participants were randomly assigned to an order of pad use (AB or BA).ResultsThe use of absorbent pad A or B did not affect the parameters of sleep or the quality of sleep. The results obtained with use of either absorbent pad did not differ significantly from the control condition and were within the normal limits.ConclusionThere was no significant difference in sleep quality between the follicular phase and the menstrual period; in addition, the use of different absorbent pads over consecutive nights during the same menstrual cycle was not associated with changes in sleep.
Arbeitsmedizin – Quo vadis?
Authors: Hofmann Friedrich , Reschauer Georg , Stößel Ulrich 
Published: July 2011

Einleitung
Der Beitrag versucht, eine kritische Standortbestimmung der akademischen Arbeits- und praktischen Betriebsmedizin in Deutschland zu geben. Der zu begrüßenden paradigmatischen Öffnung des Faches stehen aber erhebliche Entwicklungshindernisse entgegen.
Sozialkapitalbasierte Public Health-Strategie für die Arbeitswelt
Authors: Badura Bernhard 
Published: July 2011

Einleitung
Der Sozialkapitalansatz erfreut sich einer großen Beliebtheit in unterschiedlichen wissenschaftlichen Disziplinen. Elinor Ostrom gewann den Nobelpreis für ihre Arbeit zum Nutzen des Sozialkapitals.
The effects of costly exploration on optimal investment timing
Authors: Nishihara Michi , Shibata Takashi 
Published: July 2011

AbstractThis paper investigates a principal–agent model in which an owner (principal) optimizes a contract with a manager (agent) who has been delegated to undertake an investment project. In the model, we explore the effects of costly exploration by which the manager learns the real value of development cost. We show that high exploration cost can lead to a pooling policy not contingent on project type. Further, and more notably, we show that, in the presence of asymmetric information, higher exploration cost leads to wealth transfer from owner to manager and can ultimately improve social welfare.
Comparison of nasal cytology and symptom scores in patients with seasonal allergic rhinitis, before and after treatment
Authors: Özgür A , Arslanoğlu S , Etıt D , Demıray U , Önal H K 
Published: July 2011

AbstractObjective:To evaluate symptom scores and nasal smear cytology findings in seasonal allergic rhinitis patients, before and after treatment.Methods:Twenty-nine consecutive adult patients with seasonal allergic rhinitis were evaluated prospectively. They received mometasone furoate nasal spray and cetirizine for 21 days. Nasal and ocular symptom scores were recorded before and after treatment. Nasal cytology was also assessed as a means of determining treatment.Results:The combined use of an intranasal corticosteroid and an oral antihistamine caused a significant improvement in nasal and ocular symptom scores. Cytological evaluation revealed significant reduction in nasal eosinophil, neutrophil and goblet cell counts after three weeks' treatment.Conclusion:Symptom scoring systems are widely used for the evaluation of drug efficacy in allergic rhinitis treatment. When investigating the disease and evaluating treatment efficacy, objective as well as subjective methods are needed. Nasal cytological assessment is a simple, objective method which provides valuable information about the nasal mucosa.
Prevalence of haemorrhagic fever with renal syndrome in mainland China: analysis of National Surveillance Data, 2004–2009
Authors: LIU X. , JIANG B. , BI P. , YANG W. , LIU Q. 
Published: July 2011

SUMMARYThe monthly and annual incidence of haemorrhagic fever with renal syndrome (HFRS) in China for 2004–2009 was analysed in conjunction with associated geographical and demographic data. We applied the seasonal autoregressive integrated moving average (SARIMA) model to fit and forecast monthly HFRS incidence in China. HFRS was endemic in most regions of China except Hainan Province. There was a high risk of infection for male farmers aged 30–50 years. The fitted SARIMA(0,1,1)(0,1,1)12 model had a root-mean-square-error criterion of 0·0133 that indicated accurate forecasts were possible. These findings have practical applications for more effective HFRS control and prevention. The conducted SARIMA model may have applications as a decision support tool in HFRS control and risk-management planning programmes.
Selection of Rattus norvegicus oocytes for in vitro maturation by brilliant cresyl blue staining
Authors: Alcoba Diego Duarte , da Rosa Braga Bianca Letícia , Sandi-Monroy Nathallie Louise , Proença Letícia Auler , Felix Lopes Rui Fernando , de Oliveira Alexandre Tavares Duarte 
Published: July 2011

SummaryThe objective of this work was to evaluate the rate of meiosis resumption and nuclear maturation of rat (Rattus norvegicus) oocytes selected for in vitro maturation (IVM) after staining of cumulus–oocyte complexes (COCs) with blue cresyl brilliant (BCB) using different protocols: exposure for 30, 60 or 90 min at 26 μM BCB (Experiment 1), and exposure for 60 min at 13, 20 or 26 μM BCB (Experiment 2). In Experiment 1, the selection of oocytes exposed to BCB for 60 min was found to be the most suitable, as meiosis resumption rates in the BCB+ group (n = 35/61; 57.37%) were the closest to the observed in the control (not exposed) group (n = 70/90; 77.77%) and statistically higher than the values observed for the BCB− group (n = 3/41; 7.32%). Additionally, the more effective evaluation of diagnostic tests (sensitivity and negative predictive value 100%) was observed in COCs exposed for 60 min. In Experiment 2, the 13 μM BCB+ group presented rates of meiosis resumption (n = 57/72; 72.22%) similar to the control group (n = 87/105; 82.86%) and higher than other concentration groups. However, this results of the analysis between BCB− oocytes was also higher in the 13 μM BCB group (n = 28/91; 30.78%) when compared with BCB− COCs exposed to 20 μM (n = 3/62; 4.84%) or 26 μM (n = 3/61; 4.92%) BCB. The nuclear maturation rate in the 13 μM BCB group was similar between BCB+ or BCB− oocytes. The 20 μM BCB group had a lower rate of nuclear maturation of BCB− oocytes than other groups. Thus, our best results in the selection of Rattus norvegicus oocytes by staining with BCB were obtained using the concentration of 13 μM and 20 μM, and an incubation period of 60 min.
CAM-CM: a signal deconvolution tool for in vivo dynamic contrast-enhanced imaging of complex tissues
Authors: Chen Li , Chan Tsung-Han , Choyke Peter L. , Hillman Elizabeth M. C. , Chi Chong−Yung , Bhujwalla Zaver M. , Wang Ge , Wang Sean S. , Szabo Zsolt , Wang Yue 
Published: July 2011

Abstract
Summary: In vivo dynamic contrast-enhanced imaging tools provide non-invasive methods for analyzing various functional changes associated with disease initiation, progression and responses to therapy. The quantitative application of these tools has been hindered by its inability to accurately resolve and characterize targeted tissues due to spatially mixed tissue heterogeneity. Convex Analysis of Mixtures – Compartment Modeling (CAM-CM) signal deconvolution tool has been developed to automatically identify pure-volume pixels located at the corners of the clustered pixel time series scatter simplex and subsequently estimate tissue-specific pharmacokinetic parameters. CAM-CM can dissect complex tissues into regions with differential tracer kinetics at pixel-wise resolution and provide a systems biology tool for defining imaging signatures predictive of phenotypes.
Availability: The MATLAB source code can be downloaded at the authors′ website www.cbil.ece.vt.edu/software.htm
Contact: yuewang@vt.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Drought effects on damage by forest insects and pathogens: a meta‐analysis
Authors: Jactel Hervé , Petit Jérôme , Desprez‐Loustau Marie‐Laure , Delzon Sylvain , Piou Dominique , Battisti Andrea , Koricheva Julia 
Published: July 2011

AbstractIn the context of climate change, the effects of prolonged or more severe droughts on pest and pathogen damage are a major concern for forest ecosystems. To date, there is great uncertainty about the direction, magnitude and sources of variation in responses to drought by insects and fungi. We report the outcomes of a meta‐analysis of 100 pairwise comparisons of insect pest or pathogen damage to water‐stressed and control trees from 40 publications. The type of feeding substrate for insects and fungi and the water stress severity emerged as the main factors influencing the level of damage in water‐stressed trees. Overall, primary damaging agents living in wood caused significantly lower damage to the water‐stressed trees compared with the control, whereas primary pests and pathogens living on foliage caused more damage to water‐stressed trees, in all cases irrespective of stress severity. In contrast, damage by secondary agents increased with stress severity, which was best estimated by the ratio between the predawn leaf water potential in stressed trees and the xylem pressure inducing 50% loss in hydraulic conductance due to cavitation, a species‐specific index of drought tolerance. Insect and fungus feeding behaviour, affected tree part, and water stress severity are therefore proposed as three important predictors of forest damage in drought conditions.
Time to clarify – the value of advanced practice nursing roles in health care
Authors: Lowe Grainne , Plummer Virginia , O’Brien Anthony Paul , Boyd Leanne 
Published: July 2011

Lowe G., Plummer V., O’Brien A.P. & Boyd L. (2012) Time to clarify – the value of advanced practice nursing roles in health care. Journal of Advanced Nursing68(3), 677–685.AbstractAim.  This article presents a discussion of the importance of providing meaningful advanced practice nursing role definition and clarity to improve international standards of nursing titles and scopes of practice.Background.  A plethora of international literature exists discussing advanced practice nursing roles and their contribution to healthcare delivery in various countries. However, lack of consistency around title, role definition and scope of practice remains.Data sources.  CINAHL and Medline databases were searched using ‘nurse practitioner’, ‘nurse practitioner role’, ‘nurse practitioner practice’, ‘nurse practitioner in public health’, ‘advanced practice nursing roles’ and ‘development of new nursing roles’ with articles limited to years 1995–2010. Citations used in those articles were also explored. All cited articles were in the English language.Discussion.  This article supports the need to strengthen the Nurse Practitioner role in health care and professional clarity is identified as a strategy to enhance this. Themes around role clarity, professional identity, ability to enhance healthcare provision and inter‐professional issues are examined. The need to more clearly articulate advanced nursing roles in light of the evolution of the Nurse Practitioner role is highlighted. Much work has already occurred in this domain and a means of adapting and broadening these developments for a wider, more global audience whilst maintaining local context is discussed.Conclusion.  Although evidence exists that advanced practice nursing roles are increasing internationally, uncertainty around role clarity remains. This is problematic because the valuable contribution of nursing roles is lost, if the ability to clearly express their function does not exist.
External validation of pharmacokinetic and pharmacodynamic models of microemulsion and long‐chain triglyceride emulsion propofol in beagle dogs
Authors: LEE S. ‐H. , PARK H. ‐W. , KIM M. ‐J. , NOH M. ‐H. , YOON H. ‐S. , CHOI B. ‐M. , LEE E. ‐K. , NOH G. ‐J. 
Published: July 2011

Lee, S.‐H., Park, H.‐W., Kim, M.‐J., Noh, M.‐H., Yoon, H.‐S., Choi, B.‐M., Lee, E.‐K., Noh, G.‐J. External validation of pharmacokinetic and pharmacodynamic models of microemulsion and long‐chain triglyceride emulsion propofol in beagle dogs. J. vet. Pharmacol. Therap. 35, 329–341.This study aimed at assessing the predictive performance of a target‐controlled infusion (TCI) system, which incorporates canine PK–PD models for microemulsion and long‐chain triglyceride emulsion (LCT) propofol and at investigating time independency of propofol effect on the observed electroencephalographic approximate entropy (ApEn) in TCI. Using a crossover design with a 7‐day washout period, 28 healthy beagle dogs were randomized to receive TCI of both formulations in a stepwise or constant manner. Plasma propofol concentrations and ApEn were measured at preset intervals. Pooled biases, inaccuracies, divergences, and wobbles in pharmacokinetic and pharmacodynamic predictions were 2.1% (95% CI: −0.8 to 4.9), 18.1% (15.6–20.5), 1.9%/h, 7.3% (5.4–9.3), and −0.5% (−2.6 to 1.6), 8.7% (7.3–10.1), 2.5%/h, 6.0% (4.1–7.2) for microemulsion propofol, and −9.3% (−11.6 to −6.9), 20.1% (18.2–22.0), 5.1%/h, 7.6% (6.1–9.1) and 5.6% (4.1–7.1), 8.0% (6.9–9.3), 4.7%/h, 4.1% (3.1–5.1) for LCT propofol. Observed ApEn values over time were statistically not different across all time points in a TCI with constant manner. Canine PK–PD model of microemulsion propofol showed good predictive performances. Propofol effect (ApEn) was time independent as long as time is allowed for equilibration.
Co‐administration of rectal BCG and autoclaved Leishmania major induce protection in susceptible BALB/c mice
Authors: SOUDI S. , HOSSEINI A. Z. , HASHEMI S. M. 
Published: July 2011

SummaryWe examined the protective effect of autoclaved Leishmania major (ALM) vaccine in combination of either rectal or subcutaneous BCG on susceptible BALB/c mice. One month after BCG vaccination, BALB/c mice were immunized subcutaneously twice with ALM + alum at 3 weeks intervals. Three weeks after booster injection, 5 × 105 stationary phase L. major promastigotes were inoculated subcutaneously in one footpad. Immunological evaluation at before and post infectious challenge showed strong proliferative responses in the spleen cells of the rectal immunized group after stimulating with parasite lysate. High level of interferon gamma was induced in the spleen, and significant increase in the serum ratio of IgG2a/IgG1 was observed only in rectal immunized group. Rectal immunized mice showed comparable nitric oxide production and iNOS induction in peritoneal macrophages (P ≤ 0·05). The obtained results in rectal BCG vaccinated group showed no mortality but low parasite burden in the liver and spleen. In conclusion, the results of our study indicated that co‐administration of rectal BCG and ALM induced protective type 1 immune responses against L. major infection. This safe and effective mucosal vaccine could be useful in prevention of human leishmaniasis infections.
Arabidopsis ARP endonuclease functions in a branched base excision DNA repair pathway completed by LIG1
Authors: Córdoba‐Cañero Dolores , Roldán‐Arjona Teresa , Ariza Rafael R. 
Published: July 2011

SummaryBase excision repair (BER) is an essential cellular defence mechanism against DNA damage, but it is poorly understood in plants. We used an assay that monitors repair of damaged bases and abasic (apurinic/apyrimidinic, AP) sites in Arabidopsis to characterize post‐excision events during plant BER. We found that Apurinic endonuclease‐redox protein (ARP) is the major AP endonuclease activity in Arabidopsis cell extracts, and is required for AP incision during uracil BER in vitro. Mutant plants that are deficient in ARP grow normally but are hypersensitive to 5‐fluorouracil, a compound that favours mis‐incorporation of uracil into DNA. We also found that, after AP incision, the choice between single‐nucleotide or long‐patch DNA synthesis (SN‐ or LP‐BER) is influenced by the 5′ end of the repair gap. When the 5′ end is blocked and not amenable to β‐elimination, the SN sub‐pathway is abrogated, and repair is accomplished through LP‐BER only. Finally, we provide evidence that Arabidopsis DNA ligase I (LIG1) is required for both SN‐ and LP‐BER. lig1 RNAi‐silenced lines show very reduced uracil BER, and anti‐LIG1 antibody abolishes repair in wild‐type cell extracts. In contrast, knockout lig4−/− mutants exhibit normal BER and nick ligation levels. Our results suggest that a branched BER pathway completed by a member of the DNA ligase I family may be an ancient feature in eukaryotic species.
Chromoblastomycosis: a clinical and molecular study of 18 cases in Rio de Janeiro, Brazil
Authors: Mouchalouat Marcelle de F. , Gutierrez Galhardo Maria Clara , Zancopé‐Oliveira Rosely Maria , Monteiro Fialho Paulo Cezar , de Oliveira Coelho Janice Mery C. , Silva Tavares Patrícia Morais , Francesconi do Valle Antonio Carlos 
Published: July 2011

AbstractBackground  Chromoblastomycosis (CBM) is a chronic subcutaneous mycosis caused by dematiaceous fungi.Methods  We described epidemiological data, clinical presentation, and treatment of 18 cases of CBM diagnosed in Rio de Janeiro, Brazil. Diagnosis was obtained by mycological, histopathological findings demonstrating typical muriform cells with confirmation of isolated by DNA sequencing of the ribosomal internal transcribed spacer.Results  The majority of patients were male (72.2%) ranging from 39 to 83 years old, farm laborers and construction workers. The duration of disease varied from four months to 32 years. The most common presentations were verrucous form in ten (55.6%) patients, followed by tumoral in three (16.7%) patients, primarily of moderate (55.6%) and severe (38.9%) intensity. Lower (44.4%) and upper limbs (33.3%) were the most affected sites. Fonsecaea pedrosoi isolated from 14 (77.8%), and Cladophialophora carrionii isolated from one case (5.6%). Fifteen patients (83.3%) were treated. Six patients (40%) received oral itraconazole 200–400 mg/day, five patients (33.3%) received oral itraconazole 200–400 mg/day combined with fluconazole 200 mg/day, and four (26.7%) patients were submitted to surgery. The duration of therapy varied from 12 to 48 months. Cure rate was 80% (12/15). No relapse was observed after two years of follow‐up.Conclusions  Success was due to attending a center with specialized clinical care, laboratory support, and pharmaceutical care.